LOCUS       DAJVBX010000001        71116 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.001, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000001 DAJVBX010000000
VERSION     DAJVBX010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 71116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 71116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..71116
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.001"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            132..5731
                     /locus_tag="OPV72_000001"
                     /pseudo
     CDS             132..5731
                     /locus_tag="OPV72_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001169948.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter adhesin BigA"
     gene            5925..6094
                     /locus_tag="OPV72_000002"
                     /pseudo
     CDS             5925..6094
                     /locus_tag="OPV72_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhfL family protein"
     gene            complement(6238..7242)
                     /gene="trpS"
                     /locus_tag="OPV72_000003"
     CDS             complement(6238..7242)
                     /gene="trpS"
                     /locus_tag="OPV72_000003"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HCR9912428.1"
                     /translation="MTKPIVFSGAQPSGELTIGNYMGALRQWVNMQDDYHCIYCIVDQ
                     HAITVRQDAQQLRKATLDTLALYLACGIDPEKSTIFVQSHVPEHAQLGWALNCYTYFG
                     ELSRMTQFKDKSARYAENINAGLFDYPVLMAADILLYQTNLVPVGEDQKQHLELSRDI
                     AQRFNGLYGDIFKVPEPFIPKSGARVMSLLEPTKKMSKSDDNRNNVIGLLEDPKSVVK
                     KIKRAVTDSDEPPVVRYDVKEKAGVSNLLDILSAVTGQSIPELEKQFEGKMYGHLKGE
                     VAEAVSGMLSELQERYHRFRNDEAFLQKVMKDGAEKASARAAETLKAVYEAIGFVAKP
                     "
     gene            complement(7235..7993)
                     /gene="gph"
                     /locus_tag="OPV72_000004"
     CDS             complement(7235..7993)
                     /gene="gph"
                     /locus_tag="OPV72_000004"
                     /EC_number="3.1.3.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycolate phosphatase"
                     /protein_id="HCR9912429.1"
                     /translation="MNKLQNIRGVAFDLDGTLVDSAPGLAAAVDMALYALELPVAGEE
                     RVITWIGNGADVLMERALTWASQERATLRKTMGKPPVDEDIPAEEQVRILRKLFDRYY
                     GEVAEEGTFLFPHVADTLGALHASGLSLGLVTNKPTPFVAPLLESLDIAKYFSVVIGG
                     DDVQNKKPHPEPLLLVASRLGMTPEQMLFVGDSRNDIQAAKAAGCPSVGLTYGYNYGE
                     VIALSEPDVIYDSFNDLLPALGLPHSDNQEIKND"
     gene            complement(7986..8663)
                     /gene="rpe"
                     /locus_tag="OPV72_000005"
     CDS             complement(7986..8663)
                     /gene="rpe"
                     /locus_tag="OPV72_000005"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HCR9912430.1"
                     /translation="MKQYLIAPSILSADFARLGEDTAKALAAGADVVHFDVMDNHYVP
                     NLTIGPMVLKSLRQYGITAPIDVHLMVKPVDRIVPDFAAAGASIITFHPEASEHVDRT
                     LQLIKEHGCKAGLVFNPATSLSYLDYVMDKLDVILLMSVNPGFGGQSFIPQTLDKLRE
                     VRRRIDASGYDIRLEVDGGVKVNNIGEIAAAGADMFVAGSAIFDKPDYKKVIDEMRSE
                     LAKVSHE"
     gene            complement(8681..9517)
                     /gene="dam"
                     /locus_tag="OPV72_000006"
     CDS             complement(8681..9517)
                     /gene="dam"
                     /locus_tag="OPV72_000006"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine-specific DNA-methyltransferase"
                     /protein_id="HCR9912431.1"
                     /translation="MKKNRAFLKWAGGKYPLLDDIKRHLPKGECLVEPFVGAGSVFLN
                     TDFSRYILADINSDLISLYNIVKLRTDEYVQASRELFMPETNQAEVYYQLREEFNTCQ
                     DPFRRAVLFLYLNRYGYNGLCRYNLRGEFNVPFGRYKRPYFPEAELYHFAEKAQNAFF
                     YCESYADSMARADKSSVVYCDPPYAPLSATANFTAYHTNSFSLTQQAHLAEIAENLVS
                     NRIPVLISNHDTALTREWYQLAKLHVVKVRRSISSNGGTRKKVDELLALYQPGVATPA
                     RK"
     gene            complement(9698..10975)
                     /gene="damX"
                     /locus_tag="OPV72_000007"
     CDS             complement(9698..10975)
                     /gene="damX"
                     /locus_tag="OPV72_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DamX"
                     /protein_id="HCR9912432.1"
                     /translation="MDEFKPEDELKPDPSDRRTGRSRQSSERDNEPQINFDDVDLDAD
                     DRRPTRTRKARSEEPEVEEEYESDEDDTVDEERVERRPRKRKKAAHKPASRQYMMMGV
                     GVLVLLLLIIGIGSALKAPSTSSSEPSASGEKSIDLSGNAADQANATQPAPGATSAEQ
                     TAGNTSQDISLPPISSTPMQGQSPVVADGQQRVEVQGDLNNALTQNPEQMNNVAVNST
                     LPTEPATVAPVRNGSTTRQAAVSEPAERHTTRPERKQAVIELKKPQTTAKTTTAEPKK
                     PVAPVKRTEPAAPAATPKATTTTAAPQATASAAPVQTAKPAQASTTPVAGGGKSAGNV
                     GALKSAPSSHYTLQLSSSSNYDNLNGWAKKENLKNYVVYETTRNGQPWYVLVTGMYAS
                     KEDAKRAVSTLPADVQAKNPWAKPLHQVQADLK"
     gene            complement(11073..12161)
                     /gene="aroB"
                     /locus_tag="OPV72_000008"
     CDS             complement(11073..12161)
                     /gene="aroB"
                     /locus_tag="OPV72_000008"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HCR9912433.1"
                     /translation="MERITVTLGERSYPITIAAGLFNEPASFLPLKSGDQVMLVTNET
                     LAPLYLDKVRGVLERAGVNVDSVILPDGEQYKSLTVLDTVFTALLKKPHGRDTTLVAL
                     GGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQP
                     ASVVVDLDCLKTLPARELASGLAEVIKYGIILDADFFTWLEGNLDALLRLDGPAMAYC
                     IRRCCELKAEVVAADEREAGLRALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGIVMAA
                     RASERLGQFSSADTQRIIALLERAGLPVNGPCEMSAQDYLPHMLRDKKVLAGELRLVL
                     PLTIGKSEVRGGVSHEVVLSAIADCQQA"
     gene            complement(12218..12739)
                     /gene="aroK"
                     /locus_tag="OPV72_000009"
     CDS             complement(12218..12739)
                     /gene="aroK"
                     /locus_tag="OPV72_000009"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004709337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase AroK"
                     /protein_id="HCR9912434.1"
                     /translation="MAEKRNIFLVGPMGAGKSTIGRQLAQQLNMEFYDSDQEIEKRTG
                     ADVGWVFDVEGEDGFRNREEKVINELTEKQGIVLATGGGSVKSRETRNRLSARGVVVY
                     LETTIEKQLARTQRDKKRPLLQVEAPPREVLEALANERNPLYEEIADVTIRTDDQSAK
                     VVANQIIHMLESN"
     gene            complement(13204..14442)
                     /gene="hofQ"
                     /locus_tag="OPV72_000010"
     CDS             complement(13204..14442)
                     /gene="hofQ"
                     /locus_tag="OPV72_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA uptake porin HofQ"
                     /protein_id="HCR9912435.1"
                     /translation="MKRWIAIILIVLMPAAQAGKAAKVTLVVDDVPVVQVLQALAEQE
                     RQNLVVSPDVSGTLSLHLTDVPWKQALQTVVNSAGLVLRQEGNILHVHSQAWQKEHSA
                     RQDAERLRLQANLPLENRSISLQYADAGELAKAGEKLLSAKGTIMVDKRTNRLLLRDN
                     RAALAELEKWVSQMDLPVAQVELAAHIVTINEKSLRELGVKWTLADATQAGAVGDVTT
                     LSSDLSVAAATSRVGFNIGRINGRLLDLELSALEQKQQLDIIASPRLLASHLQPASIK
                     QGSEIPYQVSSGESGATSVEFKEAVLGMEVTPTVLQKGRIRLKLHISQNVPGQVLQQA
                     DGEVLAIDKQEIETQVEVKSGETLALGGIFSRKNKSGSDSVPLLGDIPWLGQLFRHDG
                     KEDERRELVVFITPRLVATE"
     gene            complement(14357..14758)
                     /locus_tag="OPV72_000011"
     CDS             complement(14357..14758)
                     /locus_tag="OPV72_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2531 family protein"
                     /protein_id="HCR9912436.1"
                     /translation="MKVSRGVLLCFCLLTLTGMRDPFRPPEDRCRIAELSQWRYQGAV
                     RKGERWTGILKDSQQKWRRVEEGQTLENGWTIVRLTAEALTLTTGKNCAPPQWRWLRQ
                     GADNEAMDSHNTDSLDARRAGGKSGESDAGG"
     gene            complement(14748..15221)
                     /locus_tag="OPV72_000012"
     CDS             complement(14748..15221)
                     /locus_tag="OPV72_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9912437.1"
                     /translation="MNALFDIWYGMSRRGRVFCWCAGVLCLTLTVALSVGYPGWKTLD
                     TQHARLSQQREAARQQWRHLRRLSVAAEPLFGRTIENPRPFSPLDFQAPPLRLLHWQP
                     SAQGGEMALKTSWDAVPSLFVRLAESEMSVSRFSLRREGAELLITLQLERLANEG"
     gene            complement(15205..15744)
                     /locus_tag="OPV72_000013"
     CDS             complement(15205..15744)
                     /locus_tag="OPV72_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilN domain-containing protein"
                     /protein_id="HCR9912438.1"
                     /translation="MAHSVNLLPWRRQHYVARLRLWCVVWGASLLLIASLATIARLVF
                     WQEGRINELLLTAENGRTTALAANIPQLQQRQRQQQARLQRQAQRELTQAWQSILTDL
                     ANLLPEQAWLTSLNYQQETLELEGLARTFDALLTLETSLRHYVSFPLNRTGATRQDAQ
                     GRWQFHYQLTRSAARERAL"
     gene            complement(15744..16523)
                     /locus_tag="OPV72_000014"
     CDS             complement(15744..16523)
                     /locus_tag="OPV72_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein HofM"
                     /protein_id="HCR9912439.1"
                     /translation="MAFKTWQIGLHIQQHEALAIAVIRGASGWSLQRWWRLPLMNAST
                     AEGTIPDPQSLAHVLRPWSRELPLRHRIYLSFPANRTLQRAFPHPPMRLREREQVAWL
                     SQTMARELDMDPDLLRFDFQDDALSPAFNVTAVQSKEISELLTLAQTLNVRIAAVTPD
                     ACALQRLLPFIPSGRQCLVWRDESQWLWATRYAWGRKSAREAMTLHDLAATLSVVPEH
                     ISLCAEGEFDPWRAVTVRQPPVPPDGYRFAIALGLAMGEIR"
     gene            16644..19196
                     /gene="mrcA"
                     /locus_tag="OPV72_000015"
     CDS             16644..19196
                     /gene="mrcA"
                     /locus_tag="OPV72_000015"
                     /EC_number="2.4.1.129"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312265.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase/peptidoglycan
                     DD-transpeptidase MrcA"
                     /protein_id="HCR9912440.1"
                     /translation="MKFVKYLLILAVCCILLGAGSIYGLYRYIEPQLPDVATLKDVRL
                     QIPMQVYSADGELIAQYGEKRRIPVTLDQIPPEMINAFIATEDSRFYEHHGIDPVGIF
                     RAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEAFLAIRIEQLLNKNEIL
                     ELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLSLSEMAVIAGLPKAPSTFNPLYSMDRA
                     VARRNVVLSRMLSEGYITQAQYDQARSEPIDANYHAPEIAFSAPYLSEMVRQEMYNRY
                     GESAYEDGYRIYTTITRKVQQAAQQAVRNNVLDYDMRHGYSGPANVLWKVGETAWDSK
                     KITDTLKALPTYGPLLPAVVTSANPQEATAALADGTSVSLHMEGMRWARPYRSDTQQG
                     PTPRKVTDVVQTGQQIWVRQVDNDWWLAQVPEVNSALVSLNPQTGAVLALVGGFDFNQ
                     SKFNRATQALRQVGSNIKPFLYTAAMDKGLTLASMLNDVPISRWDAGAGSDWRPKNSP
                     PQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAQNIVHTESLALGSA
                     SFTPMQVARGYAVMANGGFLIDPYFISKIENDQGGVIFEAKPKIACTECDIPVIYGNT
                     QKSDVLENTNVEEVAVSQEQQNSAVPMPELEQANQALVAQNGTQEYAPHVINTPLAFL
                     IKSALNTNIFGEPGWMGTGWRAARDLKRRDIGGKTGTTNSSKDAWFSGYGPGVVTSVW
                     IGFDDHRRDLGRTTASGAIKDQISGYEGGAKSAQPAWDAYMKAVLEGVPEQPLTPPPG
                     IVTVNIDRSTGQLASGGNSREEYFIEGTQPTQQAVHEVGTTIIDNGETHELF"
     gene            complement(19292..19855)
                     /gene="nudE"
                     /locus_tag="OPV72_000016"
     CDS             complement(19292..19855)
                     /gene="nudE"
                     /locus_tag="OPV72_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000045725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP compounds hydrolase NudE"
                     /protein_id="HCR9912441.1"
                     /translation="MSKSLQKPTILKVETVAQSRLFNVESVDLEFSNGVRRVYERMRP
                     STREAVMIVPIVDEHLILIREYAVGTESYELGFSKGLIDPGETVFEAANRELKEEVGF
                     GAHNLTFLKKLSMAPSYFSSKMNIVVAEDLYPESLEGDEPEPLPQVRWPLAHLMDLLE
                     DPDFNEARNVSALFLVREWLKAQGRIA"
     gene            20178..22310
                     /gene="igaA"
                     /locus_tag="OPV72_000017"
     CDS             20178..22310
                     /gene="igaA"
                     /locus_tag="OPV72_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="intracellular growth attenuator protein IgaA"
                     /protein_id="HCR9912442.1"
                     /translation="MSTILIFIAALLACSLLAIWRFRVKSRRGSLPWFSAFQDAQTRK
                     LLPEERSAVENYLDNLSQIQQVPGPTGASAAPISLTLNAESNSVVILTHSITRYGITT
                     DDPNKWRYYLDSVEVHLPPFWEQYINDENNVELILTDTLPLVISLNGHTLQEYMQESR
                     GYALQNTASTQASIRGEESEQIELLNIRQETHEEYALSRPAGLREALLIVASFLLFFF
                     CLITPDVFVPWMIGGAILLLAAGLWGLFAPPSKSALREIHCLRGTPRRWGLFGENNQE
                     QINNISLGIIDLIYPAHWQPYITQDLGQQTDIDIYLDRHVARQGRFLSLHDEVKNFPL
                     QHWLRSTVIAIGSLLVLFMLLFWIPLDMPIKFTLSWMKGAQTIEATTVKQLEKAGVRV
                     GDTLHLSGKGMCNIHSGATWSGQSNSPFMPFDCSQIIWNDAPALPLPESDLVNKAMAL
                     SQAVNRQLHPKPEDDSRVSASLRSAIQKSGMVLLDDFGDIVLKTADLCAAEDECVRLK
                     NALVNLGNSKDWNALVKRANAGKLDGVNVLLRPVSAESLENLVTTSTAPFISRETARA
                     AQSLNSPAPGGFLIASDEGSELVDQAWPSTPLYDYPAQEQWSAFQRLAQTLMQTPFSA
                     EGIVTSVYTDANGTQHISLHRIPDKSGWWRYLGTTLLMLAMIVSAVYNGIQAFRRYQR
                     HRTRMADIQEYYESCLNPRLTVSPENLI"
     gene            22375..23043
                     /gene="yrfG"
                     /locus_tag="OPV72_000018"
     CDS             22375..23043
                     /gene="yrfG"
                     /locus_tag="OPV72_000018"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006893127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP/IMP nucleotidase"
                     /protein_id="HCR9912443.1"
                     /translation="MHIDIDWQNVDTVLLDMDGTLLDLAFDNYFWQKLVPETYGAQQG
                     ISPQDAQEYIRQQYHAVQHTLNWYCLDYWSERLGLDICAMTTAQGPRAVLRDDTVPFL
                     NALKASGKRRILLTNAHPHNLAVKLEHTGLASHLDLLLSTHTFGYPKEDQRLWRAVTE
                     ETGISAEKTLFIDDSEPILDAAARFGIRYCLGVTNPDSGLAEKHYTRHPSLNDYRRLI
                     PSLK"
     gene            23054..23455
                     /gene="hslR"
                     /locus_tag="OPV72_000019"
     CDS             23054..23455
                     /gene="hslR"
                     /locus_tag="OPV72_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated heat shock protein Hsp15"
                     /protein_id="HCR9912444.1"
                     /translation="MKEKSSVEVRLDKWLWAARFYKTRALAREMIEGGKVHYNGQRSK
                     PSKIVELNATLTLRQGNDERTVIVKAITEQRRPASEAVALYEETAESVEKREKMAQAR
                     KLNALTMPHPARRPDKKERRDLLRFKHGDSE"
     gene            23480..24358
                     /gene="hslO"
                     /locus_tag="OPV72_000020"
     CDS             23480..24358
                     /gene="hslO"
                     /locus_tag="OPV72_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417860.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HCR9912445.1"
                     /translation="MPQHDQLHRYLFENFAVRGELVTVSETLQQILDNHNYPQSVKTV
                     LAELLVATSLLTATLKFAGDITVQLQGDGPLSLAVINGNNQQQMRGVARVQGDIPDNA
                     DLKTLVGNGYLVITITPEEGERYQGVVGLEGDTLAACLEDYFLRSEQLPTRLFIRTGD
                     VDGKPAAGGMLLQVMPAQNAQAEDFDHLAMLTETIKSEELLTLPANDVLWRLYHEEEV
                     TLYDPQEVEFKCTCSRERCAGALKTLPDEEVDSILAEEGEIDMHCDYCGNHYLFNAMD
                     IAEIRNNASPADPQVH"
     gene            complement(24469..26178)
                     /locus_tag="OPV72_000021"
     CDS             complement(24469..26178)
                     /locus_tag="OPV72_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4153 domain-containing protein"
                     /protein_id="HCR9912446.1"
                     /translation="MESVALSRTTRWGMLLTGLLQGVLCYLLMAWLVPQNSDWLFYGM
                     PATIALSSMLLLTVVSFKQRALWGWLGLIFVVVLAMSGWLKWQVEAVEKWRLAELLWL
                     YGLRLVLMAMLVLPWMQYQLHSQTGSARYPQFYLRLWHNVLTLFIVLVANGLFWLVLL
                     LWSALFRLVGIRFFSTLFFETEAFIYVTIGLITALAVILARTQSRLVAAVQKLLTLIA
                     TGLLPVVSLLALLFIVTLPFTGLEAISARVSATGLLSTLTLMLLLLVAIVNEPQKRVL
                     PYPRVLRGMISASLCVAPIYMLLAGWALWVRIQQYGWTPDRLYGALTASVLLVWSFGY
                     LIGLLRRGRDPDEWQGKVILSVSLLTLVILLLLASPVLDVWRISVNSHMARYHSGKIT
                     ADQISLYMLDHSGKPGQEALKSLRDDEAFTQNRKRNRELMTFLQRNKVPPTADDLARV
                     VMIAPGSQKPDAAFWAFVKEQSYSDASCLEPDACVLVSQDLNGDGQPEQVLYNFIVAE
                     SQVYGLKEGKWTQKAFARLPDGFSKTQLLHAIAGHRLDSAPKAWRDIIVDGQRLDVDY
                     YNE"
     gene            26558..28177
                     /gene="pckA"
                     /locus_tag="OPV72_000022"
     CDS             26558..28177
                     /gene="pckA"
                     /locus_tag="OPV72_000022"
                     /EC_number="4.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462403.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HCR9912447.1"
                     /translation="MRVNNLTPQDLKAYGINDVQDIVYNPSYDTLYQEELNPGLEGYE
                     RGVLTNLGAVAVDTGIFTGRSPKDKYIVRDDTTRDTLWWSDKGKGKNDNKPLSQETWQ
                     HLKGLVTHQLSGKRLFIVDAFCGANADTRLSVRFITEVAWQAHFVKNMFIRPTDEELV
                     GFKPDFIVMNGAKCTNPQWKEQGLNSENFVAFNLTERIQLIGGTWYGGEMKKGMFSVM
                     NYLLPLKGIASMHCSANVGEKGDVAVFFGLSGTGKTTLSTDPKRRLIGDDEHGWDDDG
                     VFNFEGGCYAKTIKLSKEAEPEIYHAIRRDALLENVTVREDGTVDFDDGSKTENTRVS
                     YPIYHIDNIVKPVSKAGHATKVIFLTADAFGVLPPVSRLTANQTQYHFLSGFTAKLAG
                     TERGVTEPTPTFSACFGAAFLTLHPTQYAEVLVKRMQAAGAQAYLVNTGWNGTGKRIS
                     IKDTRAIIDAILNGSLDNAETFRLPLFDLAIPTELPGVDTHILDPRNTYASPEQWQEK
                     ATALAKLFIENFEKYTDTPAGEALVSAGPKL"
     gene            complement(28252..29604)
                     /gene="envZ"
                     /locus_tag="OPV72_000023"
     CDS             complement(28252..29604)
                     /gene="envZ"
                     /locus_tag="OPV72_000023"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     EnvZ"
                     /protein_id="HCR9912448.1"
                     /translation="MRRMRFSPRSSFARTLLLIVTLLFVSLVTTYLVVLNFAILPSLQ
                     QFNKVLAYEVRMLMTDKLQLEDGTQLVVPPAFRREIYRELGISLYTNEAAEEAGLRWA
                     QHYEFLSHQMAQQLGGPTEVRVEVNKSSPVVWLKTWLSPNIWVRVPLTEIHQGDFSPL
                     FRYTLAIMLLAIGGAWLFIRIQNRPLVDLEHAALQVGKGIIPPPLREYGASEVRSVTR
                     AFNHMAAGVKQLADDRTLLMAGVSHDLRTPLTRIRLATEMMGEEDGYLAESINKDIEE
                     CNAIIEQFIDYLRTGQEMPMEMADLNSVLGEVIAAESGYEREINTALQAGSIQVKMHP
                     LSIKRAVANMVVNAARYGNCWIKVSSGTESHRAWFQVEDDGPGIKPEQRKHLFQPFVR
                     GDSARSTSGTGLGLAIVQRIIDNHNGMLEIGTSERGGLSIRAWLPVPVARVQGTTKEA
                     "
     gene            complement(29601..30320)
                     /gene="ompR"
                     /locus_tag="OPV72_000024"
     CDS             complement(29601..30320)
                     /gene="ompR"
                     /locus_tag="OPV72_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014646135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator OmpR"
                     /protein_id="HCR9912449.1"
                     /translation="MQENYKILVVDDDMRLRALLERYLTEQGFQVRSVANAEQMDRLL
                     TRESFHLMVLDLMLPGEDGLSICRRLRSQSNPMPIIMVTAKGEEVDRIVGLEIGADDY
                     IPKPFNPRELLARIRAVLRRQANELPGAPSQEEAVIAFGKFKLNLGTREMFREDEPMP
                     LTSGEFAVLKALVSHPREPLSRDKLMNLARGREYSAMERSIDVQISRLRRMVEEDPAH
                     PRYIQTVWGLGYVFVPDGSKA"
     gene            30546..31019
                     /gene="greB"
                     /locus_tag="OPV72_000025"
     CDS             30546..31019
                     /gene="greB"
                     /locus_tag="OPV72_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015703675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreB"
                     /protein_id="HCR9912450.1"
                     /translation="MKTPLITREGYETLKQELNYLWREERPEVTKKVTWAASLGDRSE
                     NADYQYNKKRLREIDRRVRYLTKCMENLKIVDYSPQQEGKVFFGAWVEIENDDGDTLK
                     FRIVGYDEIFGRKDYISIDSPMARALLKKEVGDLAVVNTPVGEANWYVNAIEYVK"
     gene            31118..33448
                     /locus_tag="OPV72_000026"
     CDS             31118..33448
                     /locus_tag="OPV72_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312276.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HCR9912451.1"
                     /translation="MMNDSFCRIIAGEIQANAGQVEAAVRLLDEGNTVPFIARYRKEI
                     TGGLDDTQLRNLETRLGYLRELEDRRQAILKSISEQGKLTDELAGAINATLSKTELED
                     LYLPYKPKRRTRGQIAIEAGLEPLADLLWNEPSHDPDVKAAKYIDGDKGVADTKAALD
                     GARYILMERFAEDAALLAKVRDYLWKNAHLVATVVSGKEEEGAKFRDYFDHHEPIANV
                     PSHRALAMFRGRNEGILQLSLNADPQFDEPPKESYCEQIIMDHLGLRLNNAPADSWRK
                     GVVSWTWRIKVLMHLETELMGTVRERAEDEAINVFARNLHDLLMAAPAGLRATMGLDP
                     GLRTGVKVAVVDGTGKLVATDTIYPHTGQAAKAATVIAALCEKYHVELVAIGNGTASR
                     ETERFYLDVQKQFPNVTAQKVIVSEAGASVYSASELAAQEFPDLDVSLRGAVSIARRL
                     QDPLAELVKIDPKSIGVGQYQHDVSQTQLARKLDAVVEDCVNAVGVDLNTASVPLLTR
                     VAGLTRMMAQNIVAWRDENGQFQNRQQLLKVSRLGPKAFEQCAGFLRINHGDNPLDAS
                     TVHPEAYPVVERILAATQQALKDLMGNSNELRHLKAADFTDDKFGVPTVSDIIKELEK
                     PGRDPRPEFKTAQFADGVETMNDLLPGMILEGAVTNVTNFGAFVDIGVHQDGLVHISS
                     LSTKFVDDPHTVVKAGDIVKVKVLEVDLQRKRIALTMRLDEQPGETAARRGGGADRAQ
                     GNRPASKAAKPRGRDAQPAGNSAMMDALAAAMGKKR"
     gene            33885..34112
                     /gene="feoA"
                     /locus_tag="OPV72_000027"
     CDS             33885..34112
                     /gene="feoA"
                     /locus_tag="OPV72_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transporter A"
                     /protein_id="HCR9912452.1"
                     /translation="MQFTPDTAWKITGFAREISPAYRQKLLSLGMLPGSSFNVVRVAP
                     LGDPIHIETRRVSLVLRKKDLALIEVEAVSC"
     gene            34131..36449
                     /gene="feoB"
                     /locus_tag="OPV72_000028"
     CDS             34131..36449
                     /gene="feoB"
                     /locus_tag="OPV72_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(2+) transporter permease subunit FeoB"
                     /protein_id="HCR9912453.1"
                     /translation="MKKLTIGLIGNPNSGKTTLFNQLTGARQRVGNWAGVTVERKEGQ
                     FATTDHQVTLVDLPGTYSLTTISSQTSLDEQIACHYILSGDADLLINVVDASNLERNL
                     YLTLQLLELGIPCIVALNMLDIAEKQQVRIDVDALSTRLGCPVVPLVSTRGRGIEALK
                     LAIDRHNANDNVELVHYAQPLLREAGFLADAMAQEMPLQQRRWLGLQMLEGDIYSRAY
                     AGEAAQNLDTSLARLKDEMDDPALHIADARYQCIAAICDVVSNTLTAEPSRFTRAVDK
                     IILNRFLGLPIFLFVMYLMFLLAINIGGALQPLFDAGSVAIFIHGIQWIGYTLHFPDW
                     LTIFLAQGLGGGINTVLPLVPQIGMMYLFLSFLEDSGYMARAAFVMDRLMQALGLPGK
                     SFVPLIVGFGCNVPSVMGARTLDAPRERLMTIMMAPFMSCGARLAIFAVFAAAFFGQN
                     GALAVFSLYVLGIVMAVLTGLMLKHTIMRGEASPFVMELPVYHVPHIKSLIIQTWQRL
                     KGFVLRAGKVIIIVSIFLSAFNSFSLSGKIVDNINDSALASVSRVITPVFKPIGVHED
                     NWQATVGLFTGAMAKEVVVGTLNTLYTAENIQDEAFNPADFHLGDELLGAVDDTWQSL
                     KDTFSLSVLANPIEASKGDGEMATGAMGVMDQKFGSAAAAYSYLIFVLLYVPCISVMG
                     AIARESSRGWMSFSILWGLNIAYSLATLFYQVTSFSQHPTYSLICILAVIVFNVVVLS
                     LLRRARSRVDIELLATRKSVTSCCSGTAGNCH"
     gene            36462..36698
                     /gene="feoC"
                     /locus_tag="OPV72_000029"
     CDS             36462..36698
                     /gene="feoC"
                     /locus_tag="OPV72_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[Fe-S]-dependent transcriptional repressor FeoC"
                     /protein_id="HCR9912454.1"
                     /translation="MASLIQVRDLLALRGRMEATQISHTLHAPQPMIDAMLNQLEIMG
                     KAVRIPEEPDGCLSGSCKSCPEGKACLREWWALR"
     gene            36933..37859
                     /locus_tag="OPV72_000030"
     CDS             36933..37859
                     /locus_tag="OPV72_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HCR9912455.1"
                     /translation="MATSTTSTPHDAVFKQFLCHPDTARDFLEIHLPSTLRQICNLNT
                     LRLESGSFIEEDLRPHYSDILWSLETSEGDGYIYVVIEHQSTPDAHMAFRLMRYAMAA
                     MQRHLEAGHKTLPLVVPMLFYHGNRSPYPFSLCWLDEFADPVMARKLYATAFPLVDIT
                     VVPDDEIMRHRRVALLELIQKHIRQRDLMGLVEQLVALLVKGYANDTQLQSLFNYMMH
                     TGDAARFNTFIRQVAMRIPQHKEKIMTIAERLRQEGHRNGLQKGLQQGKQEGQRLAAL
                     RIARSMLNDGFDRDTVLRVTGLAPADLASESH"
     gene            complement(37895..38665)
                     /gene="bioH"
                     /locus_tag="OPV72_000031"
     CDS             complement(37895..38665)
                     /gene="bioH"
                     /locus_tag="OPV72_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pimeloyl-ACP methyl ester esterase BioH"
                     /protein_id="HCR9912456.1"
                     /translation="MNDIWWQTYGEGNCHLVLLHGWGLNAEVWHCIREELGSHFTLHL
                     VDLPGYGRSSGFGAMTLEEMTAQVAKNAPDQAIWLGWSLGGLVASQMALTHPERVQAL
                     VTVASSPCFSAREGWPGIKPEILGGFQQQLSDDFQRTVERFLALQTLGTETARQDART
                     LKSVVLAQPMPDVEVLNGGLEILKTVDLREALKNVNMPFLRLYGYLDGLVPRKIAPLL
                     DTLWPHSTSQIMAKAAHAPFISHPAAFCQALMTLKSSL"
     gene            38703..39386
                     /gene="gntX"
                     /locus_tag="OPV72_000032"
     CDS             38703..39386
                     /gene="gntX"
                     /locus_tag="OPV72_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein GntX"
                     /protein_id="HCR9912457.1"
                     /translation="MLTVPGLCWLCRMPLALSHWGICSVCARAVRQRVSLCPQCGLPA
                     GHPSLPCGRCLQKPPPWQRLVSVSDYTPPLSLLVHQLKFTRRSEIAAALARLLLQEVL
                     MARRSTGLPLPDRIVSVPLWSRRHWRRGFNQSDLLCQPLAHWLGCAWDSQTITRVRAT
                     ATQHHLSARLRKRNLKNAFRLELPVQGLHMVIVDDVVTTGSTVAEIAQLLLRNGAATV
                     QVWCLCRTL"
     gene            39445..40020
                     /gene="nfuA"
                     /locus_tag="OPV72_000033"
     CDS             39445..40020
                     /gene="nfuA"
                     /locus_tag="OPV72_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016942932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S biogenesis protein NfuA"
                     /protein_id="HCR9912458.1"
                     /translation="MIRISDAAQAHFAKLLANQKEGTQIRVFVINPGTPNAECGVSYC
                     PPDAVEATDTALKFDLLTAYVDELSAPYLEDAEIDFVTDQLGSQLTLKAPNAKMRKVA
                     DDAPLMERVEYALQSQINPQLAGHGGRVSLMEITDEGYAILQFGGGCNGCSMVDVTLK
                     EGIEKQLLNEFPELKGVRDLTEHQRGEHSYY"
     gene            40397..41713
                     /gene="gntT"
                     /locus_tag="OPV72_000034"
     CDS             40397..41713
                     /gene="gntT"
                     /locus_tag="OPV72_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate transporter"
                     /protein_id="HCR9912459.1"
                     /translation="MPLVIVAIGVILLLLLMIRFKMNGFIALVLVALAVGLMQGMPLD
                     KVIGSIKAGVGGTLGSLALIMGFGAMLGKMLADCGGAQRIATTLIAKFGKKHIQWAVV
                     LTGFTVGFALFYEVGFVLMLPLVFTIAAAANIPLLYVGVPMAAALSVTHGFLPPHPGP
                     TAIATIFHADMGKTLLFGTILAIPTVILAGPVYARFLKGIDKPIPEGLYSAKTFTEEE
                     MPGFGVSVWTSLVPVILMAMRAVAEMILPKGHAFLPVAEFLGDPVMATLIAVLIAMFT
                     FGLNRGRSMDQINDTLVSSIKIIAMMLLIIGGGGAFKQVLVDSGVDKYIASMMHETNV
                     SPLLMAWSIAAVLRIALGSATVAAITAGGIAAPLIATTGVSPELMVIAVGSGSVIFSH
                     VNDPGFWLFKEYFNLTIGETIKSWSMLETIISVCGLIGCLLLGMVV"
     gene            complement(41832..43913)
                     /gene="malQ"
                     /locus_tag="OPV72_000035"
     CDS             complement(41832..43913)
                     /gene="malQ"
                     /locus_tag="OPV72_000035"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HCR9912460.1"
                     /translation="MENKRLDSAALAAGISPSYINAHGKPQSIGAETKRRLLAAMHGT
                     TTGPQAVVPNVKVYTAGKKMALPVEGRGEFAWLLTTEEGEHYKGRVTGGKKLNLPATL
                     PEGYHTLTLTQDEQRTHCRIIVAPPRCYEPQALLEGKKLWGACVQLYTLRSEKNWGIG
                     DFGDLKSMLVDVATRGGAFIGLNPIHALYPANPESASPYSPSSRRWLNVIYIDVNAVE
                     DFRLSEEAQAWWQMPATQQKLRQARDAQWVDYATVTALKITALRMAWTRFAARDDAQM
                     AEFRHFIAREGESLYWQAAFDALHAYQVKEDGQRWGWPAWPEAYQSVESPAVKQFCEA
                     HREEVEFYLWLQWLAWRQFAACWDTCQSFKLPIGLYRDLAVGVAEGGAETWCDRELYC
                     LKASVGAPPDILGPLGQNWGLPPMDPHIIVARAYEPFIDLLRANMQNCGALRIDHVMS
                     LLRLWWIPYDETADQGAYVHYPVDDLLSILALESQRHRCMVIGEDLGTVPVEIVGKLR
                     DSGVYSYKVLWFENDLEKNFRAPGAYPQQSMAVASTHDLPTLRGYWECGDLTLGKALG
                     LYPDEVILRGLYEDRERAKQGLLDALHKYGCLPKRAGHKALLMSMTPTLNRGLQRYIA
                     DSNSGLLGLQPEDWLDMADPVNVPGTSDQYKNWRRKLSASLEAMFADEGVNKLIKDLD
                     KRRKAAAKKKK"
     gene            complement(43923..46316)
                     /gene="malP"
                     /locus_tag="OPV72_000036"
     CDS             complement(43923..46316)
                     /gene="malP"
                     /locus_tag="OPV72_000036"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrin phosphorylase"
                     /protein_id="HCR9912461.1"
                     /translation="MSQPTFNKDQFQAALTRQWQRFGLLSASDMTPRQWWQAVSGALA
                     ELLSAQPVAQPTKGQRHVNYISMEFLIGRLTGNNLLNLGWYQDVSDVLKAHDINLTDL
                     LEEEVDPALGNGGLGRLAACFLDSMATVGQSATGYGLNYQYGLFRQSFVEGKQMEAPD
                     DWHRGSYPWFRHNEALDVQVGIGGKVTKEGRWKPGFVITGQSWDLPVLGYRNGVAQPL
                     RLWQATHAHPFDLTKFNDGAFLRAEQQGIDAEKLTKVLYPNDNHTAGKKLRLMQQYFQ
                     CACSVADILRRHHLAGRKLHELADYEVIQLNDTHPTIAIPELLRVLLDEHQMSWDDAW
                     AITSKTFAYTNHTLMPEALECWDERLIKALLPRHMQIIKQINDRFKALVDNTWPGDKQ
                     VWAKLAVVHDRQVRMANMCVVSGFAVNGVAALHSDLVVKDLFPEYHQLWPNKFHNVTN
                     GITPRRWIKQCNPQLAALLDKTLKKEWANDLDQLINLEKYADDATFRQQYRDIKRANK
                     ERLVKFIQARTGIEISSHAIFDIQIKRLHEYKRQHLNLLHILALYKEIRENPQADRVP
                     RVFLFGAKAAPGYYLAKNIIFAINKVAEAINNDPAVGDKLKVVFLPDYCVSAAEMLIP
                     AADISEQISTAGKEASGTGNMKLALNGALTVGTLDGANVEIAEKVGEENIFIFGHTVE
                     EVKALKAKGYDPVKWRKKDKVLDAVLKELESGQYSDGDKHAFDQMLHSLGKQGGDPYL
                     VMADFAAYVEAQKQVDALYRDQEAWTRAAILNTARCGMFSSDRSIRDYQARIWQAKR"
     gene            46910..49615
                     /gene="malT"
                     /locus_tag="OPV72_000037"
     CDS             46910..49615
                     /gene="malT"
                     /locus_tag="OPV72_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator MalT"
                     /protein_id="HCR9912462.1"
                     /translation="MLIPSKLSRPVRLDHTVVRERLLAKLSGANNFRLLLVTSPAGYG
                     KTTLVSQWAAGKNELGWYSLDEGDNQQERFASYLIAAIQQATGGHCSTSEAMAQKRQY
                     ASLTSLFAQLFIELAQWHRPLYLVIDDYHLITNPVIHDAMRFFLRHQPENFTLVVLSR
                     NLPQLGIANLRVRDQLLEIGSQQLAFNHQEAKQFFDRRLSSPIEAAESSRMCDDVAGW
                     ATALQLIALSARQNHTSAHHSARRLAGINASHLSDYLVDEVLDNVDVSTRHFLLKSAI
                     LRSMNDALIVRVTGEENGQMRLEEIERQGLFLQRMDDTGEWFSYHPLFGSFLRQRCQW
                     ELAAELPEIHRAAAESWMEQGFPSEAIHHALAAGDAQMLRDILLNHAWGLFNHSELAL
                     LEESLKALPWESLLENPRLVLLQAWLMQSQHRYSEVNTLLARAEQEIKGVMDGTLHAE
                     FNALRAQVAINDGNPEEAERLAKLALDELPLAWFYSRIVATSVHGEVLHCKGNLSQSL
                     SLMQQTEQMARHHDVWHYALWSLIQQSEIQFAQGFLQAAWETQERAFQLIKEQHLEQL
                     PMHEFLVRIRAQLLWAWARLDEAEASARSGIAVLSTFQPQQQLQCLTLLVQCSLARGD
                     LDNARSQLNRLEKLLGNGRYHCDWISNADKVRVIYWQLTGDKKSAANWLRHTPKPAFA
                     NNHFLQGQWRNIARAQILLGEFEPAEIVLEELNENARSLRLMSDLNRNLLLLNQLYWQ
                     SGRKNDAQRVLLDALQLANRTGFISHFVIEGEAMAQQLRQLIQLNTLPEMEQHRAQRI
                     LRYINQHHRHKFAHFDEGFVERLLNHPDVPELIRTSPLTQREWQVLGLIYSGYSNEQI
                     AGELAVAATTIKTHIRNLYQKLGVAHRQDAVQHAQQLLKMMGYGV"
     gene            complement(49689..50447)
                     /locus_tag="OPV72_000038"
     CDS             complement(49689..50447)
                     /locus_tag="OPV72_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family transcriptional regulator"
                     /protein_id="HCR9912463.1"
                     /translation="MKQTQRHDAIIELVKKQGYVSTEELVEHFSVSPQTIRRDLNDLA
                     EQNMILRHHGGAALPSSSVNTPWHDRKATQTEEKERIARKVAAQIPNGSTLFIDIGTT
                     PEAVAHTLLGHSNLRIVTNNLNVANTLMAKEDFRIILAGGELRSRDGGIIGEATQDFI
                     AQFRLDFGILGISGIDSDGSLLEFDYHEVRTKRAIIENSRHVMLVVDHSKFGRNAMVN
                     MGSISMVDAVYTDTLPPPGVMQVIADHHIQLELC"
     gene            complement(50540..51370)
                     /gene="glpG"
                     /locus_tag="OPV72_000039"
     CDS             complement(50540..51370)
                     /gene="glpG"
                     /locus_tag="OPV72_000039"
                     /EC_number="3.4.21.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease
                     GlpG"
                     /protein_id="HCR9912464.1"
                     /translation="MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDIWLADESQ
                     AERVRVELARFIENPGDPRYLAASWQSGQTNSGLRYRRFPFLATLRERAGPVTWIVML
                     ACVVVYIAMSLIGDQTVMVWLAWPFDPVLKFEVWRYFTHIFMHFSLMHILFNLLWWWY
                     LGGAVEKRLGSGKLIVITVISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERD
                     PQSGIYLQRGLIIFALLWIVAGWFDWFGMSMANGAHIAGLIVGLAMAFVDTLNARKRT
                     "
     gene            complement(51446..51772)
                     /gene="glpE"
                     /locus_tag="OPV72_000040"
     CDS             complement(51446..51772)
                     /gene="glpE"
                     /locus_tag="OPV72_000040"
                     /EC_number="2.8.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase GlpE"
                     /protein_id="HCR9912465.1"
                     /translation="MEQFECITVEEAYQKLHQGAAVLVDIRDPQSYAMGHAPQAFHLT
                     NDTLGAFMREHGFDTAVMVMCYHGNSSKGAAQYLLQQGYDAVYSIDGGFEAWHRRFPA
                     DVANGA"
     gene            51971..53479
                     /gene="glpD"
                     /locus_tag="OPV72_000041"
     CDS             51971..53479
                     /gene="glpD"
                     /locus_tag="OPV72_000041"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate dehydrogenase"
                     /protein_id="HCR9912466.1"
                     /translation="METKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSA
                     SSKLIHGGLRYLEHYEFRLVSEALAEREVLLKMAPHIAFPMRFRLPHRPHLRPAWMIR
                     IGLFMYDHLGKRTSLPGSTGVRFGADSVLKPEIVRGFEYSDCWVDDARLVLANAQMVV
                     RKGGEVLTRTRATAARRENGLWIVEAEDIDTGKKYVWQARGLVNATGPWVKQFFDEGM
                     HLPSPYGIRLIKGSHIVVPRVHNQKQAYILQNEDKRIVFVIPWMEEFSIIGTTDVEYK
                     GDPKAVKIEESEINYLLKVYNAHFQKQLGRDDIVWTYSGVRPLCDDESDSPQAITRDY
                     TLDIHDENGKAPLLSVFGGKLTTYRKLAEHAMEKLASYYPGIGPAWTKTCVLPGGDID
                     GSREDYAAKLRRRYPFLTESLARHYSRTYGSNTEWILGEATSLLDLGEDFGHEFYEAE
                     LKYLVDHEWVRRTEDAIWRRTKEGMWLTAEQQSRITQWLAAYVEKHQLSLAS"
     gene            complement(53571..56018)
                     /gene="glgP"
                     /locus_tag="OPV72_000042"
     CDS             complement(53571..56018)
                     /gene="glgP"
                     /locus_tag="OPV72_000042"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010436446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen phosphorylase"
                     /protein_id="HCR9912467.1"
                     /translation="MNAPFTYASPTLSVEALKHSIAYKLMFTIGKDPVIANKHEWLNA
                     TLFAVRDRLVERWLRSNRAQLSQETRQVYYLSMEFLIGRTLSNALLSLGIYDDVKGAL
                     EAMGLDLEELIDEENDPGLGNGGLGRLAACFLDSLATLGLPGRGYGIRYDYGMFKQNI
                     VDGRQKESPDYWLEYGNPWEFKRHNTRYKVLFGGRIQQEGKKARWIETEEILAVAYDQ
                     IIPGYDTDATNTLRLWNAQASSEINLGKFNQGDYFAAVEDKNHSENVSRVLYPDDSTY
                     SGRELRLRQEYFLVSATVQDILHRHYQLHKTYENLADKIAIHLNDTHPVLSIPELMRL
                     LIDEHKFSWDDAFEVCCQVFSYTNHTLMSEALETWPVDMLGKILPRHLQIIFEINDYF
                     LKTLQEQYPNDTSLLGRASIIDESNGRRVRMAWLAVVVSHKVNGVSELHSNLMVQSLF
                     ADFAKIFPTRFCNVTNGVTPRRWLALANPPLSDVLDENIGRTWRTDLSQLSELKQHCD
                     YPLVNHAVRQAKLENKKRLAVVIAQQLNVVVNPKALFDVQIKRIHEYKRQLMNVLHVI
                     TRYNRIKENPEADWVPRVNIFAGKAASAYYMAKHIIHLINDVAKVINNDPQIGDKLKV
                     VFIPNYSVSLAQVIIPAADLSEQISLAGTEASGTSNMKFALNGALTIGTLDGANVEMQ
                     EHVGEENIFIFGNTAEEVEALRRQGYKPRDYYEKDEELHQVLTQIGNGVFNPEEPGRY
                     RDLVDSLINFGDHYQVLADYRSYVDCQDKVDELYRRPEEWTTKAMLNIANMGYFSSDR
                     TIKEYAENIWHIDPVRL"
     gene            complement(56038..57471)
                     /gene="glgA"
                     /locus_tag="OPV72_000043"
     CDS             complement(56038..57471)
                     /gene="glgA"
                     /locus_tag="OPV72_000043"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HCR9912468.1"
                     /translation="MQVLHVCSEMFPLLKTGGLADVIGALPAAQIADGVDVRVLLPGF
                     PDIRRGIPDAHVVSRRDTFAGKISLLFGHYNGVGIYLIDAPHLYERPGSPYHDTNLYA
                     YIDNVLRFALLGWVGCEMACGLDPFWRPDVVHAHDWHAGLAPAYLAARGRPAKSVFTV
                     HNLAYQGMFYAKHMDDIELPWSFFNMHGLEFNGQLSFLKAGLYYADHITAVSPTYARE
                     ITEPQFAYGMEGLLRQRHLEGRLSGILNGVDEKIWNPESDLLLASRYTRDTLEEKAEN
                     KRQLQIAMGLKVNDKVPLFAVVSRLTNQKGLDLVLEALPGLLEQGGQLALLGAGDPVL
                     QEGFLAAAAEHPGQAGVQIGYHEAFSHRIMGGADVILVPSRFEPCGLTQLYGLKYGTL
                     PLVRRTGGLADTVSDSSLENLADGIASGFVFEDSNAWSLLRAIRRAFVLWSRPSLWRF
                     VQRQAMAMDFSWQVAAKSYRELYYRLK"
     gene            complement(57471..58766)
                     /gene="glgC"
                     /locus_tag="OPV72_000044"
     CDS             complement(57471..58766)
                     /gene="glgC"
                     /locus_tag="OPV72_000044"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HCR9912469.1"
                     /translation="MVSLEKNDRVMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPA
                     VHFGGKFRIIDFALSNCLNSGIRRIGVITQYQSHTLVQHIQRGWSLFSEEMNEFVDLL
                     PAQQRMKGENWYRGTADAVTQNLDIIRCYKAEYVVILAGDHIYKQDYSRMLIDHVEKG
                     ARCTVACMPVPIKEATAFGVMAVDENDKIIDFVEKPANPPAMPGDASKSLASMGIYVF
                     DADYLYELLAADDKDDASSHDFGKDIIPKITREGMAYAHPFPLSCVQSDPQAEPYWRD
                     VGTLEAYWKANLDLASVTPELDMYDQNWPIRTHMESLPPAKFVQDRSGSHGMTLNSLV
                     SGGCIISGSVVVQSVLFPRVRINSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACIIPE
                     GMVIGENAEEDARRFYRSEEGIVLVTREMLRKLQVKQER"
     gene            complement(58781..60745)
                     /gene="glgX"
                     /locus_tag="OPV72_000045"
     CDS             complement(58781..60745)
                     /gene="glgX"
                     /locus_tag="OPV72_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen debranching protein GlgX"
                     /protein_id="HCR9912470.1"
                     /translation="MTQLAIGEATPHGATYDGHGVNFTLFSAHAERVELCVFDSRGNE
                     RRYDLPGRRGDVWHGYLAGARPGLRYGYRVHGPWQPAQGHRFNPAKLLLDPYARQVEG
                     ELKDHPLLHGGHDEPDYRDNAAVAPKSVVISDHYDWEDDAAPRTPWGKTVIYEAHVKG
                     LTYLHPELPQEIRGTYKALGHPVMVAYFKQLGITALELLPVAQFASEPRLQRMGLTNY
                     WGYNPMAMFALHPAWASSPETALDEFRDAVKALHRAGIEVILDIVLNHSAELDLDGPT
                     FSLRGIDNRSYYWIRDDGDYHNWTGCGNTLNLSHPGVVEYACECLRYWMETCHVDGFR
                     FDLASVMGRTPTFRQDAPLFAAIKACPVLSTVKLIAEPWDIGEGGYQVGNFPPPFAEW
                     NDHFRDAARRFWLPRNLTTGEFACRFAASSDVFKRNGRAPGASVNLLTAHDGFTLRDC
                     VCFNQKHNEANGEENRDGTNSNYSDNHGKEGLGGPLDLMERRRDSIHALLATLLLSQG
                     TPMLLAGDEHGHSQHGNNNAYCQDNALTWLDWQQANRGLTTFTAALIRLRQQIPALTG
                     NSWWEEGDGNVRWLNKNAQPLSADEWQNGPKLMQILLSDRFLIAINATLEVTDIVLPE
                     GEWRAVPPFAGEDNPVITAVWQGLCVFQRG"
     gene            complement(60742..62928)
                     /gene="glgB"
                     /locus_tag="OPV72_000046"
     CDS             complement(60742..62928)
                     /gene="glgB"
                     /locus_tag="OPV72_000046"
                     /EC_number="2.4.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching enzyme"
                     /protein_id="HCR9912471.1"
                     /translation="MSSRIDRDVINALIAGHFADPFSVLGMHQTQAGLEVRALLPDAT
                     DVWVIEPKTGRKVGKLECLDARGFFCGVLPRRKNFFRYQLAVTWHGQQNLIDDPYRFG
                     PLIQEMDAWLLSEGTHLRPYETLGAHADTMDGVTGTRFSVWAPNARRVSVVGQFNYWD
                     GRRHPMRLRKESGIWELFIPGAHNGQLYKFELLDANGNLRIKADPYAFEAQMRPETAS
                     MICGLPEKVTPSEERQKANQFDAPISIYEVHLGSWRRHTDNNFWLSYRELADQLVPYA
                     KWMGFTHLELLPVNEHPFDGSWGYQPTGLYAPTRRFGTRDDFRYFINAAHAAGLNVIL
                     DWVPGHFPSDEFSLAEFDGTHLYEHSDPREGYHQDWNTLIYNYGRREVSNYLVGNALY
                     WMERFGIDALRVDAVASMIYRDYSRKEGEWIPNEFGGRENLEAIEFLRNTNRIIGEQV
                     PGAVSMAEESTDFSGVTRPPETGGLGFWYKWNLGWMHDTLDYMKLDPVYRQYHHDKLT
                     FGMLYNHTENFVLPLSHDEVVHGKKSILDRMPGDAWQKFANLRAYYGWMWAFPGKKLL
                     FMGNEFAQGREWNHDASLDWHLLEGGDNWHHGVQRLVRDLNHTYRHHKALHELDFDAY
                     GFEWLVVDDNERSVLIFVRRDKAGNEIIVASNFTPVPRHDYRFGINQPGRWREILNTD
                     SMHYHGSNTGNGGVVHSDEIESHGRQHSLNLTLPPLATIWLMREGE"
     gene            complement(63304..64410)
                     /gene="asd"
                     /locus_tag="OPV72_000047"
     CDS             complement(63304..64410)
                     /gene="asd"
                     /locus_tag="OPV72_000047"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HCR9912472.1"
                     /translation="MKNVGFIGWRGMVGSVLMQRMVEERDFDAIRPVFFSTSQFGQAA
                     PTFGDTSTGTLQDAFDLDALKALDIIVTCQGGDYTNEIYPKLRESGWQGYWIDAASTL
                     RMKDDAIIILDPVNQDVITDGLNNGVKTFVGGNCTVSLMLMSLGGLFAHNLVDWVSVA
                     TYQAASGGGARHMRELLTQMGQLYGHVADELATPSSAILDIERKVTALTRSGELPVDN
                     FGVPLAGSLIPWIDKQLDNGQSREEWKGQAETNKILNTASVIPVDGLCVRVGALRCHS
                     QAFTIKLKKEVSIPTVEELLAAHNPWAKVVPNDRDITMRELTPAAVTGTLTTPVGRLR
                     KLNMGPEFLSAFTVGDQLLWGAAEPLRRMLRQLA"
     gene            64536..64910
                     /locus_tag="OPV72_000048"
                     /pseudo
     CDS             64536..64910
                     /locus_tag="OPV72_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_452851.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MarC family protein"
     gene            complement(64833..66173)
                     /gene="gntU"
                     /locus_tag="OPV72_000049"
     CDS             complement(64833..66173)
                     /gene="gntU"
                     /locus_tag="OPV72_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate transporter"
                     /protein_id="HCR9912473.1"
                     /translation="MSTLTLVLTAVGSVLLLLFLVMKARMHAFVALMVVSMGAGLFSG
                     MPLDKIAATMEKGMGGTLGFLAIVVALGAMFGKILHETGAVDQIAVKMLKSFGHNRAH
                     YAIGLAGLICALPLFFEVAIVLLISVAFSMARHTGTNLVKLVIPLFAGVAAAAAFLLP
                     GPAPMLLASQMHADFGWMILIGLCAAIPGMIIAGPLWGNFISRYVELRIPDDITEPHL
                     GEGKMPSFGFSLSLILLPLVLVGLKTIAARFVPEGSTAYEWFEFIGHPFTAILVACLV
                     AIYGLAMRQGMPKDKVMEICGHALQPAGIILLVIGAGGVFKQVLVDSGVGPALGEALT
                     GMGLPIAITCFVLAAAVRIIQGSATVACLTAVGLVMPVIEQLNFSGAQMAALSICIAG
                     GSIVVSHVNDAGFWLFGKFTGATEAQTLKTWTMMETILGTVGAIVGMIAFQLLS"
     gene            complement(66170..66703)
                     /gene="gntK"
                     /locus_tag="OPV72_000050"
     CDS             complement(66170..66703)
                     /gene="gntK"
                     /locus_tag="OPV72_000050"
                     /EC_number="2.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HCR9912474.1"
                     /translation="MSTTNHDHHVYVLMGVSGSGKSAVASAVAHQLHAAFLDGDFLHP
                     RCNIEKMASGEPLNDDDRKPWLQALNDAAFAMQRTNKISLIVCSALKKHYRDLLREGN
                     PNLSFIYLKGDFDVIESRLKARKGHFFKTQMLVTQFETLQEPGADERDVLVVDIDQPL
                     EGVVASTIEVINKGSTL"
     gene            complement(66842..67837)
                     /gene="gntR"
                     /locus_tag="OPV72_000051"
     CDS             complement(66842..67837)
                     /gene="gntR"
                     /locus_tag="OPV72_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001693277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate operon transcriptional repressor GntR"
                     /protein_id="HCR9912475.1"
                     /translation="MKKKRPVLQDVADRVGVTKMTVSRFLRNPEQVSVALRGKIAAAL
                     DELGYIPNRAPDILSNATSRAIGVLLPSLTNQVFAEVLRGIEAVTDAHGYQTMLAHYG
                     YKPEMEQERLESMLSWNIDGLILTERTHTPRTLKMIEVAGIPVVELMDSQSPCLDIAV
                     GFDNFEAARQMTAAIIARGHRHIAYLGARLDERTIIKQKGYEQAMRDAGLVPYSVMME
                     QSSSYSSGIELMRQARREYPQLDGIFCTNDDLAVGAAFECQRLGLKIPDDMAIAGFHG
                     HDIGQVMEPRLASVLTPRERMGSIGAERLLARIRGETVTPKMLDLGFTLSPGGSI"
     gene            complement(68204..68899)
                     /locus_tag="OPV72_000052"
     CDS             complement(68204..68899)
                     /locus_tag="OPV72_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004213399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pirin family protein"
                     /protein_id="HCR9912476.1"
                     /translation="MIYLRKANDRGHANHGWLDSWHTFSFADYYDPNFMGFSALRVIN
                     DDVIDAGQGFGTHPHKDMEILTYVLEGAVEHQDSMGNKEQVPAGEFQIMSAGTGVRHS
                     EYNPSKTDRLRLYQIWIIPQETGITPRYEQRRFDAAQGKQLVLSPDARDGSLKVHQDM
                     ELYRWALLKDEQSVHQIAAERRVWIQVVKGNVTINGTKATTSDGLAIWDEQAISIHAD
                     SDSEVLLFDLPPV"
     gene            complement(69023..70060)
                     /locus_tag="OPV72_000053"
     CDS             complement(69023..70060)
                     /locus_tag="OPV72_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HCR9912477.1"
                     /translation="MTLHCAFIGFGKSTTRYHLPYVLNRKDTWHVAHIFRRHAKPEEQ
                     APQYSHIHFTSDLDEVLGDPQVKLVIVCTHADSHFEYAKRALEAGKNVLVEKPFTPTL
                     AEAKVLFELARSKGLTVTPYQNRRFDSCFLTAKKAIESGKLGKIVEIESHFDYYRPVA
                     ETKPGLPQDGAFYGLGVHTMDQIISLFGRPDHVAYDIRSLRNKANPDDTFEAQLFYGA
                     LKAIVKTSHLVKIDYPKFIVHGTKGSFVKYGIDQQETSLKANIMPGEPGFAADESVGV
                     LEYVNDEGVTVKEEVKPETGDYGRVYDALYQTLTIGTPNYVKESEVLTNLEILERAFE
                     QATPATITLAK"
     gene            70527..71015
                     /gene="yhhY"
                     /locus_tag="OPV72_000054"
     CDS             70527..71015
                     /gene="yhhY"
                     /locus_tag="OPV72_000054"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HCR9912478.1"
                     /translation="MSEIVIRHAEPKDYDAIRQIHAQPEVYHNTLQVPHPSLEMWQAR
                     LTEQAGVKQLVACIDDIVVGHLSIQVTQRPRRSHVADFGICVDARWHNRGIASALIRT
                     MIDMCDNWLRVERIELTVFVDNEPAVAVYKKYGFEIEGTGKKYGLRNGEYVDTYFMAR
                     VK"
BASE COUNT        16632 a        20181 c        18539 g        15764 t
ORIGIN      
        1 tgacctgacc tggttatcgg gtgataaaat aaacactaaa tcataatttt cttctggcca
       61 tttcatcatt gcctgtatcg ctatccgcat atgtttagta cgcaaggaaa tattaattaa
      121 ggatgaactc tatgcaaaag aaaaaactta tttctatcgc tatcgcttta acgctgcaaa
      181 gttattacat tccggccatc gccgcagaga ataacgatga tgaaaaagaa tgtcccagta
      241 atatcgcctc cctgcctaaa gaaaaacgcg caaaactctc accgacctgc cttgctacat
      301 tacctgaaaa tgataatcac tggggctggg ttgctggcgg cgttgccgca ttggtcgcgg
      361 gtgtggttat tggcgttgaa aataacggtg gcggagattc tactcattct tatattcccc
      421 ctacgcccga cgatggcggc aatgtcaccc cgcccgacga tagcggcgat gacgatgtaa
      481 ccccgcccga cgatagcggc gatgacgatg tgaccccgcc cgatgacgac gacacgcccc
      541 cggatgactc tgttataacc ttcagcaacg gcgtcaccat cgataaaggc aaagacaccc
      601 tggccttcga tagcttcaaa ctggatagcg gcagcgttct cgagggtgcc gtgtggaatt
      661 attcagaaca gaacaaccag tggcagctca cccccctggg cggcaaaacg ctgaacgtca
      721 ccggttggga cgtgaccgac gctaatgccg ccgtgattga aggcacccag gaaaatggtc
      781 tctactggaa gtatgacagc cggggctatc tgatccttgc cgacgataaa accaccgtta
      841 tcagcggcga cggcgaatcg catacctccg atcgcggcat ggatatcagc ggccaggatc
      901 gcaccggcgt gattatttcc ggcaatcgaa ccgtcaacac gctcaccggg ggttccagtg
      961 tgaccgacgg cgccatcggc atggtgatca ctggcgatgg caccaccaac accatttcgg
     1021 gccactcaac ggtggacaac gccaccggcg cgctgatttc cggcaacgga accaccacca
     1081 atttcgccgg tgacattgcc gtgagcggcg gcggcaccgc catcatcatc gacggcgaca
     1141 acgccacgat taagaatact ggtacctcca ccatcaacgg cacaggctcc accggcaccg
     1201 tcattgacgg caataacgcc cgcgtcaaca atgacggtga tatgaccatc accgatggcg
     1261 gcaccggtgc tcacatcacc ggcgataacg cggttatcga taacgccggg gacaccaccg
     1321 tcagcggcac gggctcaacg gcgctgtata tcgacggcga caatgcgctc attatcaatg
     1381 aaggtaatca gactatttcc ggcggcgcca ttggtacgcg aattgacggc gacgacgccc
     1441 gtatcgccaa taccggcgat atcgccgttg atggcgcagg ctctgcggcg gcgattatta
     1501 atggcgacaa tagcagcctg acccaggcgg gcgatctgct ggtcaccgac ggcgcgatgg
     1561 gcatcatcac ctacggcgcc ggaaatgaag ccaaaaatac cggcaacgcc accgtgcgtg
     1621 atgtagactc agtggggttt gtggtcgcag gcgaacaaaa caccttcaaa aacaagggga
     1681 atattaacat cagccttaac ggcaccggcg cgctggtaag cggcaatgcg tcgcaagcga
     1741 cgctggatgg cgatattaat gtcaccgcaa cagaggacgg ggataacgtt tatcgtggcg
     1801 cgacgggcct cgacatgacg gggaataaca acacgctgaa tattatcggc agcgtcacgg
     1861 tcaacggcga ctatgacaaa gacagcgtga tggccggcag cagcgatacc cttatgggga
     1921 tgtctatcag cggcagcaat aatgcggtgg acctgagcgg cacgctcaat attaacgtca
     1981 gcgatatgag taacgtggac gaacaatatc tgaataccgt tggccttgat gtggcaggtg
     2041 atggcaatac cgtggactta gccggcggta ttaatatcaa ctacaccgaa gatgctgacg
     2101 gcctcgaatc agccgttacc agtataaaca tcagcggaga cagtagcgta acgctaagcg
     2161 gtgaatccac gctcaatatt gccaccgtcc ccggcggcgc ggtgacgctg gcgaatgtga
     2221 gaaatggcgg caacttaacg ttagatcaaa actcaacggt taatatcaat gaaacggtta
     2281 ttctttctaa ttattacatg acgcaggccc tgttaaccgc cagcggcgag ggctcctcaa
     2341 tcaataatca gggcactgtc gttgacgatg gcgccgtcgc tttattactg gcggatagcg
     2401 gcgcacaggc acaaaacagc ggcaagatta ccgcgtatgc cacaacaggg acgtccagcc
     2461 gtaatgcgat agccgcggct aacggccagg gttccaccgt taataatgaa gcggaaggga
     2521 caatcacctt agtttcatca ttaactccgt tttcaaatac cggcgcgggc aacttcccac
     2581 taatctggta caaaaatacc ctgtacgcca tgctggcaga ggactacggc gaggtgagta
     2641 acgacgccgg cgccaccata tatttgcagg gcgcaggggt atacggcgta tccgccagca
     2701 aaggcacggc gctcaacgct ggtgatatct acctggacgg ctttgtcccg acgctggatg
     2761 atgaaaataa catcaccgac aaaacttact ggacgccacc gaaactttat gtcaccagcg
     2821 ccgcgatggt cgcaggcacc accgacagcg gttatggcga tgccaccgcc accaacaccg
     2881 gcaccattaa cgtcaataac gccgggttcg gcatgatggc gcttaacggc ggtaccgcca
     2941 ttaaccaggg ggtaattaat ctgaccgctg atgcgggcgt tgaagggacc gacccgaatc
     3001 aactggtagg catggcggcg ctcaacggcg gaaccgttgt caacgatacc acaggcaaaa
     3061 tcaatattta tgccgattac ggcaagcctt tcctgaccga cggcaatagc ctgattgtta
     3121 actacggcac cgtctgtttt ggcgacgatt gccaggacag cgacgagtac aatccaacaa
     3181 acagtgacgt ttctatccct tacacagacg gcgctacgat tgccgatgcc ggaacaagta
     3241 caacgcttgg taataaagcg attgtgacag gagacgttaa taataccgga gtggtcagcg
     3301 gcgagtccat taccgtcctg gatagcggca cgctgaccaa caacgacagc ggcgttatca
     3361 atagcaacac cacggtatcc ggcaaccttg tcaatgacgg cgtcataaac ggtgcgctga
     3421 cgcaaaatgg cggcgatatc gttaataatg gcaccattga cagccgtagc ctgacgacca
     3481 acggcgtatt aactaacgca cggatggcac catggcttcc ggcgcaaaag tgactggcgc
     3541 taacagtgca atcattaacg acggtacgtt ctatcttggc tccgcgactg acgctaaaaa
     3601 tgcgtccatg ctggaaatca atgatttcgc gcaattcttt aataccggta cgttaatcct
     3661 tgataacaac aaaaatgcca ttcacctgaa tgcgaataac ggaacgctgt acaacaccgg
     3721 gacgatggag cttacggcaa cctccaataa gggcgcgatt aactattggg gcgcgggagc
     3781 ggcatttatc aatgacggta cggtaaatgc cactactgcg gtgcttgctt atgcgggggg
     3841 cggcgcaggt aatgccccgg ataaacacgc tttcttctgg aaccagtcaa acggcgtaat
     3901 caattacgat gcggataatg gccgcgccgt cgatttctcc gcctataaca attacgtagc
     3961 ggtcaacgac ggcaccatga atatcagcgg taataacgct tacggcatgt atggcggcaa
     4021 aaatgcacaa ctggtcaata acaatacgat caatttaggt acagaaggca ccaccgacac
     4081 aggcatggtc gcgatggcgc tggataaaaa tgctaccgct aatgctgtca ttgagaacaa
     4141 cggtacaatt aatatttacg ccaataactc ttacgcgttt agcgtggcgg gtgcggggca
     4201 tgtggttaat aacgggacgg tagtcattgc cgatggcgta acgggttccg gtattattaa
     4261 acagggtgac agcgttaacg tcgaagggac aaacggtaat aacggcaaca gcgacgaggc
     4321 gcattatgcc gactatacgt tgccggaaac gcctgttgaa cccggcagca acacgacctc
     4381 cggcttcgcc gccggcgaca cgtccggcgc gtccaacaac ctgaacggct acgtggttgg
     4441 cacgaacgcc gacggcagcg caggccagct taaggtcagc aacgccagca tggaaggcgt
     4501 gggtatcaat accggcttca ccgcaggcac cgccgacacc accgtcagct ttgacaacgt
     4561 ggtggagggc agcaacctca ccgacgcttc cgctatccag tccaccagcg tggtgtggaa
     4621 cgcccagggc agtcaggaca gcgacggcaa cgttgacgtc accatgacca aaaacgccta
     4681 cgccgatgtg gcaaccgacg gtagcgtgtc tgacgtggcg caggcgctgg acgctggcta
     4741 caccaacaac gagctgtaca ccagccttaa cgtaggcacc accgccgaac tcaacagtgc
     4801 gctgaaacag gtaagcggca gccaggccac tacggtattc cgtgaagccc gggtgttaag
     4861 caaccgcttc aacatgctgg ccgacgccgc gccgcagatt aaagacggcc tggcgtttaa
     4921 cgtggtggcg aaaggcgacc cgcgcgccga gctgggcaac gacacccagt acgacatgct
     4981 ggcgctgcgt cagaaactgg acttaaccgc aaaccagaac ctgacgctgg aatacggtat
     5041 cgcccgtctg gacggcgatg gttcgcaaaa agcgggcgac aacggcctga ccggcggcta
     5101 cagccagttc tttggtctga agcacagcat ggcgtttgat gaaggtctgg cgtggaataa
     5161 cagcctgcgt tatgacgtac acaacctcga cagcagccgt tctgtcgcct atggcgatgt
     5221 taacaaaatt gccgattccg atgcgcgtca gcagtacatg gagttccgta gcgagggggc
     5281 gaaaaccttc tccctgatgg acgatgcgct gaaagtgacg ccgtatgccg gggtgaaatt
     5341 ccgtcatacc atggaagatg gctacaaaga gcgcaacgct ggcgatttta acctgtcgat
     5401 gaactctggc agcgaaacag cggtggattc cattgtgggt atgaagctgg attacgccgg
     5461 gaaagacggc tggagcgcca ccgctaccct ggaaggcggc ccgaacctga gctacagcaa
     5521 gagccagcgt acagcgtcat tacagggtgc ggcgggtcaa tcgttcggcg tggatgacgg
     5581 tcaaaaaggc ggcggcatta atggcctggc aaccatcggc gtgaaatata gcagcaatga
     5641 taccgcgcta catctggatg cataccagtg gaaggaagac ggtatcagcg ataaaggctt
     5701 tatgcttaac gttaagaaaa catttcgtta aataaacgac attatataac actaatatag
     5761 gccgcttatt attaagcggc cttttttaaa tcatattccc tggtaaagat aaagtcctta
     5821 tttggactac ctgcattgtt tattaattgc tatcgtacta tacgctaaat agatcttata
     5881 tttattccac cagtagtatt cgttttatca acaaggattt tgacatgttt aaatttgtaa
     5941 aaattgccgt tgtggcaggg gttctggcga cgcttaccgc ctgtactggt catatcgaaa
     6001 acaaaaaaat aactgcagct acgattattt gctgcaccct gcaatttcta tttctaaaat
     6061 tattggcggt tgcggcccgg ctgccgatca ataatagaaa cgactgcgca gatacaaaaa
     6121 aaccgggatt tcccggtttt tttacaggtc tgataaacag tatggcacag gtgccttgtc
     6181 caacttacgt tcgttggtag gcccgataag ctagcgccat cgggcaagca attaccgtta
     6241 cggtttcgcc acaaagccaa tggcttcgta aacggctttc agcgtttcgg ccgcacgtgc
     6301 gctggctttt tccgccccgt ctttcatcac cttctgcaag aacgcttcgt cgttgcggaa
     6361 acggtgatag cgctcctgca actcagacag cattccggaa accgcctccg ccacttcgcc
     6421 tttcaaatgg ccatacattt taccttcaaa ctgtttttcc agctcaggaa tgctctgacc
     6481 ggtcacggcg gaaaggatat ccagcaggtt agagacaccc gctttctctt tcacatcata
     6541 acgcactacc ggcggctcgt cggagtcagt gaccgctcgt ttgattttct tcactaccga
     6601 tttcggatct tccaacaggc cgattacgtt attacggtta tcgtccgatt tggacatttt
     6661 cttcgtcggc tccagcaacg acatcacgcg cgcaccggat tttggaataa acggttccgg
     6721 tactttgaaa atatcgccat acagcccgtt gaaacgctgg gcgatatcgc ggctcagttc
     6781 cagatgctgc ttctgatctt cgcctaccgg caccagattg gtttggtaca gcaggatgtc
     6841 tgccgccatc agcaccgggt aatcaaacag gccggcgtta atattttccg catagcgcgc
     6901 agatttatct ttaaactgcg tcatacggct cagctcgccg aaataggtat agcagttcag
     6961 cgcccagcca agctgcgcat gttccggcac atgggactga acgaaaatag tgctcttttc
     7021 aggatcaata ccacatgcca agtacagcgc cagcgtatcc agcgtcgctt tacgtagctg
     7081 ctgcgcgtcc tgacgtacgg taatagcatg ttggtctacg atgcagtaga tgcaatgata
     7141 gtcatcctgc atgtttaccc actgacgcaa tgcccccata tagttgccaa tggtcaattc
     7201 acctgagggc tgtgcgccac taaaaacgat gggcttagtc attttttatt tcctggttat
     7261 cgctatgcgg aagcccaagt gcgggcaaaa gatcgttaaa actgtcataa atgacgtccg
     7321 gctcgctaag ggcgatcact tcgccataat tgtagccgta tgtcaggcca accgaagggc
     7381 agcccgccgc ttttgcggcc tgaatatcat tacgcgaatc gccgacaaaa agcatctgct
     7441 ccggcgtcat gcccagtcgg cttgccacca gcaacaacgg ctctggatgc ggcttcttat
     7501 tttgcacatc atcgccgccg ataaccacgc taaagtattt ggcgatatca agcgattcca
     7561 gcaacggcgc gacgaacggc gtcggcttat tcgtcaccag acctaatgac aatccgctgg
     7621 cgtgcagcgc gcccagcgtg tcggcgacat gcggaaataa aaaggtgccc tcttccgcca
     7681 cttcgccata atacctgtcg aacagtttac gcagaatgcg tacctgttcc tcggcaggaa
     7741 tatcttcatc aacgggcggt ttccccatag tcttacgcag cgtggcgcgc tcttggctag
     7801 cccaggtcag cgcgcgttcc atcaatacgt ctgcgccgtt accaatccag gtaatcacgc
     7861 gctcctcgcc cgcgaccggc agttccagcg catacagcgc catatccacc gccgcggcaa
     7921 gacccggcgc gctatccacc agcgtaccgt caagatcaaa ggcgacgccc cgaatattct
     7981 gcaacttatt catgacttac ctttgccagc tcactgcgca tttcatcaat cacttttttg
     8041 tagtcgggtt tatcgaaaat tgccgacccc gcaacaaaca tgtccgcacc agctgcggcg
     8101 atctcgccga tattgttcac cttcacgccg ccgtccactt ccaggcgaat gtcgtaaccg
     8161 gacgcatcaa tgcggcgacg cacttcgcgc agtttatcca gcgtctgcgg aataaaagac
     8221 tggccgccga agcctgggtt cacggacatc agcaggatca catccagttt gtccatgacg
     8281 taatcgagat aactgagcga cgttgccggg ttgaatacca gccccgcttt acagccgtgc
     8341 tctttaatca gctgtagcgt gcggtcaaca tgttcggagg cttccgggtg aaaggtaatg
     8401 atgctcgcgc cagcggcggc aaagtcgggc acgatacggt caaccggctt gaccatcagg
     8461 tggacatcaa taggcgcggt aataccgtac tgacgcaggg atttcagcac catcgggccg
     8521 atagtcaggt tcggcacata gtgattatcc atgacgtcaa agtgtacaac atcagcaccg
     8581 gcagccagcg ctttggcggt gtcttcaccc aggcgagcaa aatcagccga cagaattgag
     8641 ggggcaatca aatactgttt catccgcttc tccttgagaa ttattttctt gcaggcgttg
     8701 cgactcctgg ttggtacaga gccagcagtt cgtccacctt tttacgtgtg ccgccgttgc
     8761 tgcttatact gcgtctaact ttgacgacat gcaattttgc gagttgatac cactcgcgtg
     8821 tgagcgccgt atcatggttg gaaatgagca ccggtatccg gttactgacc agattctcag
     8881 cgatttccgc cagatgcgct tgttgcgtca ggctaaaact attggtgtga tacgctgtga
     8941 agttagccgt ggcggacaac ggcgcataag gcggatcgca atagaccacc gacgacttgt
     9001 ccgcacgcgc catactgtct gcgtatgact cacagtaaaa gaacgcattc tgcgcttttt
     9061 ctgcaaagtg gtacaactcc gcttccggga agtaaggtct tttataacga ccaaacggta
     9121 cattaaattc cccgcgcaag ttatagcggc agagtccgtt ataaccgtag cggttcagat
     9181 ataaaaacag taccgcccga cgaaaggggt cctggcaggt gttgaactcc tcacggagtt
     9241 ggtaatagac ctcagcctgg ttagtttcag gcataaacag ctcgcgcgaa gcctgtacat
     9301 actcgtcagt acgtaacttc acgatgttat agaggctaat aaggtcgctg ttgatatcgg
     9361 cgaggatata acgagaaaag tcggtgttaa gaaacaccga tccggcaccc acaaaaggtt
     9421 cgacaaggca ctcgcctttt ggcaaatgtc gtttgatatc atcaagcaga gggtattttc
     9481 cccctgccca cttcaaaaaa gcgcgatttt ttttcatgct gactaactaa ttacaccttc
     9541 tccggctgtg gagaaagctc cgacagcatc ctgcgcttta ggctgtgccg cgttgcttta
     9601 cggcgcattt gacggtagca aatgcgcccc tcgcgcctgt cctgaaaaaa aatagctgtc
     9661 agcgacactc acaggcaatt gcaggacaca gcctggatta tttcagatcg gcctgaacct
     9721 gatgcaacgg ttttgcccac gggtttttcg cctgcacatc ggcaggtaag gtggacaccg
     9781 cacgtttagc atcttctttc gaagcataca tccccgttac cagcacatac cacggttgtc
     9841 cattacgcgt cgtctcgtat accacataat ttttcaggtt ctctttcttc gcccaaccgt
     9901 tcaggttgtc gtaatttgaa gaactactga gctgcaatgt gtagtggctg gatggcgcgc
     9961 tctttaatgc gccaacgttg ccggcgcttt tcccgccgcc tgcgacaggc gtcgtcgagg
    10021 cttgcgccgg cttcgcggtt tgtaccggcg cagcgcttgc cgtcgcttgc ggcgcagccg
    10081 tcgtggtggt cgctttcggc gtcgcggctg gcgctgccgg ttccgtgcgt ttcactggcg
    10141 cgaccggttt cttcggttcc gcagtggtgg ttttcgccgt ggtctgcggt ttcttaagtt
    10201 caatgacggc ctgtttacgt tccggacgcg tggtatgacg ctcggcaggt tcgctaaccg
    10261 ccgcctgacg cgtcgtgctg ccattgcgaa ctggcgcgac ggttgcaggc tctgtcggca
    10321 acgtagagtt caccgcaaca ttgttcatct gctctggatt ctgcgtcagc gcattattca
    10381 gatcgccctg cacttccacg cgctgctgac cgtcagcgac cacaggcgac tgtccctgca
    10441 tcggcgttga agaaatcggc ggcaacgaaa tatcctgcga cgtattgccc gcggtttgtt
    10501 ctgcggaggt ggcgcccggc gcaggctggg tcgcattcgc ctgatcggcg gcgttaccgg
    10561 aaagatcgat actcttttcg ccagaggccg acggctcgct ggaagacgtt gagggggctt
    10621 tcagcgcgga gccgataccg ataatcaaca gcagcagcac cagtacgcca acgcccatca
    10681 tcatgtactg acgagaggct ggcttatggg ccgctttttt acgcttacgt ggacggcgtt
    10741 caacacgctc ttcgtccacc gtatcgtctt catcggattc gtactcttct tcaacttcag
    10801 gttcttcact acgcgcttta cgcgtacgcg tcggacggcg atcgtcggca tccagatcaa
    10861 cgtcatcaaa gttgatctgc ggctcattat cgcgttctga agattgacga gaacgaccag
    10921 tacgacgatc gctgggatcg ggtttcagct cgtcttctgg tttgaattca tccatttaac
    10981 accccactca aaggttaatg cttacgacat tgcacataac ctgaagctaa aagactgaca
    11041 gctacgcaat atcagtctga cctttcttgt tgttacgcct gctgacagtc agcaatcgcg
    11101 ctaagaacga cttcgtgcga cactccgccg cgcacttcac ttttccctat ggtcagcgga
    11161 agcactaaac gcagctcccc cgctaacact tttttatctc gcagcatgtg cggcaaatag
    11221 tcctgcgcgg acatctcgca agggccattg actggcaacc cggcccgttc gagtagcgcg
    11281 atgatgcgct gcgtatcagc agaactgaac tgccccaaac gctcggatgc gcgcgcagcc
    11341 atcactatac ctgcggcaac ggcttcacca tgtaaccaat tgccatatcc catttccgct
    11401 tcaatggcgt ggccaaaggt atgcccaaga ttcagtaaag cacgtaagcc cgcttcacgc
    11461 tcgtcggcgg caacaacttc ggctttcagc tcgcaacaac gacgaataca gtacgccatc
    11521 gccgggccgt ccagacgcaa tagcgcatcc agattaccct caagccaggt gaagaagtct
    11581 gcgtcgagta taatgccgta tttgatcacc tctgccagtc ccgatgccag ttcgcgtgcg
    11641 ggaagcgttt tcaggcaatc aagatcgaca accacagaag cgggttggta aaacgcgcca
    11701 atcatgtttt tgccaagggg atggttgacg gcggtcttcc cgcccacgga agaatcaacc
    11761 tgcgacagta aggtagttgg cacctggatg aaacgaacgc ctcgctggta gctggccgcc
    11821 gcaaaaccgg taagatcgcc aatcacgccg ccgccaagcg cgaccagcgt ggtatcacga
    11881 ccatgcggtt ttttcagtaa cgccgtaaac accgtatcca gcaccgtcag gctcttatac
    11941 tgctcgccgt caggaagaat cacgctgtct acgttaacgc ccgcccgttc gagtacgccg
    12001 cgaaccttgt ccagataaag cggcgccagg gtttcgttgg tcactaacat gacctgatcg
    12061 cctgatttca gcggcaagaa tgaagctggt tcgttaaaca aaccagccgc gatggtgatc
    12121 gggtaactac gttccccgag agtgactgta atcctctcca tgacgcgaca tccaccttag
    12181 ttacttgtgc ccgcttaccc agcgtattct gcttgaatta gttgctttcc agcatatgaa
    12241 taatctggtt tgccacaacc ttagcgcttt gatcgtcggt gcgaatggtg acgtcggcaa
    12301 tctcttcgta cagcggattg cgttcgttag ccagcgcttc cagaacttcg cgaggcggtg
    12361 cttcaacctg caacagcggg cgttttttat cacgctgcgt gcgcgccagt tgtttttcga
    12421 tggtcgtttc aaggtagacc acgacgccac gcgcggagag acggttacgc gtttcacgcg
    12481 attttacaga gccaccgccg gttgccagca caataccctg tttttccgtc aattcgttga
    12541 taactttttc ttcacgatta cggaagccgt cttcaccttc aacatcgaag acccagccca
    12601 catcagctcc ggttcgtttc tcaatctctt gatcagaatc gtaaaattcc atattgagtt
    12661 gttgagctaa ctggcgccca atagtgcttt ttccggcacc cataggccca accagaaaga
    12721 tattgcgttt ctctgccatt ttttcggtac tactaagact attcgttaat ggtaaacccg
    12781 cttcacagac acccagcgca gcaggacatg aactgaaacc tcataagata ttgcgagagt
    12841 cagactgaaa attatctcaa tactcaagcg ggtttggcaa ctgaataaat caccaagcct
    12901 gattgttgca aaacccgagt tagcgttgcc gaatggcgac cagaacaaca tatccggcct
    12961 acaaattgct ctactttcaa acaattgtgc gcaatccgca gaaccaatac gtctgcatca
    13021 gcggacattc agccgtttat catcggtctt atgcacacct tcggcaaggc aaagcgcatt
    13081 aatcaatgcg taagcaacga aaagcacgac tctcaaatcg gtactccttg tatgctaaat
    13141 acatccgcac gtcaaatccc gcagatgcgt tcagtgcaaa aacagcgctt ttttatgcat
    13201 aaattattct gtcgccacca gtctgggggt gataaacacc actaattcgc gtcgctcgtc
    13261 ctctttgccg tcatggcgga agagctgacc aagccaggga atatccccca acagcggcac
    13321 gctatcgcta cccgatttat tttttcgcga aaaaatgccg cccagcgcca gcgtctcgcc
    13381 gctttttacc tctacctgcg tttcaatttc ctgtttatct atcgccagca cttcgccgtc
    13441 agcctgttgt agtacctgac cgggaacatt ctggctgata tgtaacttca ggcggatgcg
    13501 ccctttttgc aaaacggtgg gcgtcacctc cattcccagt accgcttctt taaattccac
    13561 ggaggtcgcg ccgctttcgc cgctggaaac ctgataagga atttcgctgc cttgcttgat
    13621 actggctggc tgtagatgcg aagccagcag ccgggggctg gcgataatat ccaactgctg
    13681 cttttgttcc agcgctgaca gctctaaatc cagcaggcgt ccgttaatgc gcccgatgtt
    13741 aaacccgacg cgtgaggtgg cggcggcgac ggataaatca ctggaaagcg tcgtcacgtc
    13801 acccaccgcg cccgcttgcg tcgcgtcagc cagcgtccac tttacgccca gttcccgtag
    13861 actcttttcg ttaatggtga cgatatgcgc cgccagctcc acctgcgcca ccggcagatc
    13921 catttgcgat acccattttt ccagctccgc cagggccgcg cggttatcgc gcaacagcag
    13981 gcggttggtg cgcttatcta ccatgatggt tcccttcgcg ctcaggagtt tctcgcccgc
    14041 tttcgccagt tcgccggcat cggcgtattg caggctaatg ctgcggtttt ccagcggtaa
    14101 attagcctga agccttaacc gctcggcatc ctgccgcgca ctgtgttctt tctgccaggc
    14161 ctgtgaatga acatggagaa tattcccctc ctgacgcagc accagccccg cgctattgac
    14221 caccgtctga agcgcctgtt tccacggcac atccgtcaga tgtagcgata atgtcccgct
    14281 gacgtccggc gacaccacca gattctgccg ctcctgttcg gctaaagcct gcaaaacctg
    14341 caccacagga acgtcatcaa ccaccagcgt cactttcgcc gcttttcccg cctgcgcggc
    14401 gggcatcaag actatcagta ttatggctat ccatcgcttc attgtccgct ccctgacgta
    14461 accaccgcca ctgcggcggc gcacaatttt taccggtcgt taacgttaag gcttccgccg
    14521 tcaggcggac aatcgtccaa ccgttttcca gcgtctgccc ttcttccact cgccgccatt
    14581 tttgctggct gtctttaaga atgcctgtcc atcgctcgcc tttacgcacc gcgccctgat
    14641 atcgccactg cgagagttcc gctatccggc agcgatcttc cggcgggcgg aagggatcgc
    14701 gcattcccgt caacgtcagc aaacaaaaac agagcaatac accgcggcta accttcattc
    14761 gccagtcgct ccagttgcag cgttatcaat aattccgccc cctccctacg caatgaaaac
    14821 cgacttacgc tcatctcgct ttcggccaac cggacaaaca gcgacggcac cgcatcccag
    14881 gacgttttca gcgccatttc tcccccctgc gccgatggct gccagtgcag caaacgcaag
    14941 ggaggcgcct ggaaatctaa cggcgaaaaa ggacgcggat tttcgatggt acgcccgaaa
    15001 agcggttcag ccgcgacgct cagacggcgc agatgacgcc actgttgccg ggcggcctcg
    15061 cgctgctggc ttaaccgcgc atgttgcgta tccagcgtct tccagccggg atagcccaca
    15121 gataacgcga ccgtcagcgt caggcacagc acgcctgcac accaacaaaa aacccgacca
    15181 cggcgcgaca tcccgtacca gatatcaaag agcgcgttca cgggcggcgc tcctcgttaa
    15241 ctgataatgg aactgccagc gcccttgcgc atcctgccgc gtggcgcccg tgcggtttag
    15301 cggaaaactg acatagtgac gaagtgatgt ctcaagcgtg agcagggcgt caaacgttct
    15361 cgccagccct tccagctcta gcgtctcttg ctgataattg aggcttgtca gccatgcctg
    15421 ctctggcaac aggttggcaa ggtcagtcaa gatagattgc caggcttgcg tcagttcacg
    15481 ctgcgcctga cgttgtaatc gcgcctgttg ctgtcgctga cgctgctgca actgcggtat
    15541 gttcgccgca agcgccgtcg tgcgtccgtt ttccgccgtc agtagcagtt cattaatcct
    15601 cccctcctgc caaaaaacca accgggcgat cgtcgcgagg cttgctatca gcagcaggga
    15661 cgcgccccat accacgcacc acagccgcag acgcgctaca taatgttggc gccgccaggg
    15721 aagcaaattg acagaatgcg ccatcagcgt atctccccca tggctaaacc cagcgcaatc
    15781 gcaaagcgat aaccgtccgg cggaaccggc ggttggcgga cggtaacggc gcgccagggg
    15841 tcgaattcgc cttcggcgca taacgaaata tgttccggca cgacggataa cgtcgcggca
    15901 aggtcatgca gcgtcatcgc ctctcgcgcc gatttacgcc cccacgcata gcgcgtcgcc
    15961 cacagccact ggctttcatc gcgccagacc agacattgcc gccccgaagg tataaacggc
    16021 agcaagcgct gtaacgcgca ggcatcgggc gttacagcag cgatgcgtac attgagcgtt
    16081 tgcgccagcg ttaacagctc tgaaatttct ttgctttgca cggcggtaac gttgaacgcg
    16141 gggctcagcg catcgtcctg aaagtcgaaa cgcaataagt ccggatccat atccagctca
    16201 cgcgccatcg tttgtgaaag ccatgcgact tgctcacgtt cccgcagacg catcggcgga
    16261 tgtggaaaag cgcgttgcaa tgtccgattt gcgggaaaag agagataaat acggtgacgt
    16321 agcggcagct cgcggctcca gggtcgcagt acgtgagcca gcgattgcgg gtcaggaatc
    16381 gtaccctctg ccgtggaggc gttcatcagc ggcagtcgcc accaacgttg cagggaccag
    16441 cccgatgcgc cgcgaataac ggcgatggcc agcgcttcat gctgctgaat atgcaatcct
    16501 atttgccagg ttttaaaagc cataacggtc gatctcctta tcacccgtcg cgttaacggg
    16561 tatatcaatg cgtctggctt gcctttatac taccgcgcgt ttgtttataa actgcccaaa
    16621 tgacactaaa tgggaaatct ccagtgaagt tcgtaaagta tttattgatc cttgcagtat
    16681 gttgcatcct gctgggagca ggctcgattt atggccttta tcgctatatt gagccgcagc
    16741 tacctgacgt cgcgacattg aaagatgtgc gtttacaaat tccgatgcag gtttacagcg
    16801 cggatggcga acttatcgcg caatatggcg aaaaacgccg tattcccgtt acgctcgatc
    16861 aaattccgcc ggaaatgatc aacgccttta tcgccaccga agatagccgc ttttatgagc
    16921 atcacggtat tgacccggta ggtattttcc gtgcggccag cgtcgcgctc ttctccggtc
    16981 acgcatcgca gggagcaagt accattaccc agcaactggc gcgaaacttc ttccttagcc
    17041 ccgaacgcac gctgatgcgc aagatcaagg aagcgtttct ggcgattcgt attgagcagt
    17101 tgctgaataa aaatgagatc ctcgaactct atctgaacaa gatctatctc ggctaccgcg
    17161 cctatggcgt tggcgcggcg gcacaggtct actttggtaa gacggtcgac cagcttagtt
    17221 taagcgaaat ggcggttatc gccgggctac ctaaagcgcc ttctaccttt aacccgctct
    17281 actcgatgga tcgggcggtg gcgcgccgta acgtagtgct ctcacgaatg ttaagcgagg
    17341 gatatatcac tcaggcgcag tacgatcagg cccgtagcga acctatcgac gcaaattatc
    17401 acgcgccgga aatcgccttc tccgcgcctt atctgtcgga aatggtgcgc caggaaatgt
    17461 ataaccgtta tggcgaaagc gcctatgaag atggttatcg tatttacacg accatcaccc
    17521 gcaaagtgca gcaggccgcg caacaggcgg tgcgtaataa cgtgctggac tatgacatgc
    17581 gccacggtta tagcggcccg gcgaatgtgc tatggaaagt gggcgaaacg gcgtgggaca
    17641 gtaaaaaaat taccgatacg ttgaaagcgt tgccgaccta cggaccgctg cttcccgccg
    17701 tggtcaccag cgctaatccg caagaggcga ccgctgcgct tgccgacggt acgtccgttt
    17761 cgctacatat ggaaggaatg cgttgggcgc ggccttaccg ctcggataca cagcaggggc
    17821 cgacgccgcg taaagttacc gatgtcgtcc agacaggtca gcaaatctgg gttcgtcagg
    17881 tggataacga ctggtggctg gcgcaggtac cggaagtgaa ctccgcgctg gtttcgctta
    17941 acccgcaaac tggcgcggta ctggcgctgg tcggcggttt cgattttaat cagagtaaat
    18001 ttaaccgcgc gacgcaagct ttgcgtcagg tggggtcgaa catcaaaccg ttcctctaca
    18061 ccgccgcaat ggataaaggc ctgacgctcg ccagtatgct caacgatgtg ccgatttccc
    18121 gctgggacgc cggggccggt tcagactggc gtccgaaaaa ctctccgccg cagtacgccg
    18181 gaccgattcg tttacgccag gggctggggc agtcgaaaaa cgtggtgatg gtacgcgcca
    18241 tgcgcgccat gggcgtcgac tatgcggcgg agtatctgca acgcttcggc ttcccggcgc
    18301 agaatatcgt gcataccgaa tcgctggcgc tgggctccgc ctccttcacg ccgatgcagg
    18361 ttgcgcgcgg ttatgcggtg atggcgaacg gcggtttcct gatcgacccg tatttcatca
    18421 gcaagattga gaacgatcag ggcggcgtga tcttcgaagc gaaaccgaaa atcgcctgca
    18481 cggagtgcga tatcccggtc atttacggca atacgcagaa atccgacgtg ctggaaaaca
    18541 ccaatgtgga agaggtcgcg gtttcgcaag agcagcaaaa cagcgccgta ccgatgcctg
    18601 agctggaaca ggcaaaccag gcgctggtcg cgcaaaacgg cacgcaggag tacgcgccgc
    18661 atgtgatcaa tacgccgctg gcgtttctga tcaaaagcgc gctgaacacc aatatcttcg
    18721 gcgaacccgg ctggatgggt accggctggc gtgcggcgcg cgaccttaaa cgtcgcgata
    18781 tcggcggcaa aaccggtacg accaacagct cgaaagacgc atggttctcc ggctatggtc
    18841 ctggcgtcgt cacttccgta tggatcggct ttgacgatca ccgccgtgat ttaggccgca
    18901 ccaccgcttc cggcgcgatc aaagatcaaa tctccggcta tgagggcggc gcgaagagcg
    18961 cgcaacctgc atgggacgcc tatatgaaag ccgtgctgga aggcgtgccg gaacagccgc
    19021 taacgccgcc gccgggcatc gtcacggtga atatcgaccg cagtaccgga caactggcga
    19081 gcggcggtaa cagccgtgaa gagtatttca tcgaaggcac gcagccgaca caacaggcgg
    19141 tacacgaggt gggaaccacc attattgata atggtgaaac acacgaactg ttctgatcaa
    19201 aaaaggcgct ccggcgcctt ttttattgtg tttagcggat gacggcgaac ggggagacaa
    19261 actttccgtt ggcttgatca acgccgcgcc atcaggcaat tcggccctgc gctttcaacc
    19321 actcgcgtac cagaaacagc gcgctgacgt tgcgggcctc gttaaaatcg gggtcttcca
    19381 gcagatccat taaatgcgcc agcggccagc gtacctgcgg caatggctca ggctcgtcgc
    19441 cttccagcga ctccggatag agatcttccg ccaccacgat attcattttg ctggaaaaat
    19501 aagagggcgc catgctgagt ttttttaaga aggtcaggtt atgcgcgcca aacccgacct
    19561 cttctttgag ctcccggttc gccgcttcaa aaacggtctc gcccgggtcg atcaatcctt
    19621 tcgagaagcc cagctcatag gattcggttc ccaccgcata ctcacgaata agaatcagat
    19681 gctcatcaac gatcggcaca atcattaccg cctcacgggt tgatggtcgc atacgttcat
    19741 acacgcgacg cacgccgttg ctgaactcca gatccacgct ttctacgtta aacagtcggg
    19801 attgtgcgac ggtttccact ttcagaatgg tgggtttttg taatgatttg ctcattgtga
    19861 gaatctttgc agtgtaatct gtggtcattg tgcgacatac cgcacggttt cggcaatgcg
    19921 aattgccgtt tatttacatt tatgtaacgt aataaaaatt aattcttatt tcaaattaaa
    19981 agtcaatagg ttgaaataac tccaggaatt tgctgatatt ccgtttttgg tggtattgct
    20041 atgatttgcc ttcactggga tgcgctttac aatgctcaag ttcaactcca cgcttgccga
    20101 tagccaacca cagaaaaatg tttattggac agggtgcgac tgaccacgcc tgacagactt
    20161 agtaagatgg ggaaagcatg agcaccattc tgatttttat agctgctttg ctggcctgct
    20221 ctctactggc aatatggcgg ttccgggtaa agtccagacg agggagctta ccgtggttca
    20281 gcgcctttca ggacgcgcaa acgcgtaaac tgttgcccga agagcgcagc gcggtagaaa
    20341 actatctcga taaccttagc cagatccagc aagttccggg gccgacaggc gccagtgctg
    20401 cgcccatctc gctgacgctg aacgcggaaa gcaacagtgt cgtgatactg acccactcca
    20461 tcacccgcta cggcattacc actgacgatc ctaataaatg gcgctactac ctcgactccg
    20521 tcgaagtcca tctgccgcct ttctgggaac agtacatcaa tgatgaaaac aacgttgagc
    20581 taatcctcac ggatacgctg ccgctggtga tctctttaaa cggccatacg ctgcaagagt
    20641 atatgcagga gtcgcgcggc tacgcgctac agaatacggc ctctacgcag gcgtcgattc
    20701 gcggcgaaga gagcgagcag attgagctgt tgaacatccg tcaggagacc cacgaagaat
    20761 atgcgctcag ccgcccggct ggcttgcgcg aagcattgtt aatcgtcgcc tcctttttgt
    20821 tattcttttt ctgtctgata acgccagacg tttttgtacc gtggatgata ggcggcgcga
    20881 tcctgctgct ggcagccgga ctttgggggc tttttgcgcc gccgtcgaaa agcgcgctgc
    20941 gggaaattca ctgtctgcgg ggaacgcccc gccgctgggg actgtttggg gagaataatc
    21001 aggagcagat taacaatatt tccctgggca tcatcgacct tatttaccct gcccactggc
    21061 aaccttacat tacgcaggat cttgggcaac aaacggatat tgatatttac cttgatcgcc
    21121 atgtcgcccg ccagggccgt tttttatccc tgcatgatga agtgaaaaac ttcccgttgc
    21181 agcactggtt acgcagcact gttattgcta tcggttcgct gctggtgttg tttatgctgc
    21241 tgttctggat cccgttggat atgccaatca agttcacgct atcgtggatg aaaggcgcgc
    21301 aaaccattga agcgacaacg gtaaaacagc ttgaaaaggc tggcgtacgg gtgggcgata
    21361 cgctgcacct gagcggtaaa ggaatgtgta atattcattc cggggcgacc tggagcgggc
    21421 agtctaactc accgtttatg ccgttcgatt gctcgcaaat catctggaat gacgcgcctg
    21481 cgctaccgct gccggaatca gatctggtga ataaagcgat ggcgctaagc caggcggtaa
    21541 atcgtcagct ccatccaaaa cccgaagacg actcgcgcgt aagcgcatct ttacgctccg
    21601 cgatccaaaa atcgggcatg gtattattag atgactttgg cgatattgtt ctgaaaaccg
    21661 ctgatttgtg cgcggcggaa gacgagtgcg tgcgcctgaa aaatgcgctg gttaatctcg
    21721 gtaacagtaa ggactggaac gcgctggtga aacgcgcgaa cgccggcaaa ctggacggcg
    21781 tcaacgtgct gctacgcccc gtaagcgcag agtcgctgga aaatctggtc acgacctcaa
    21841 cggcgccgtt tatttctcgc gagaccgcgc gtgccgccca gtcgctgaat agccccgctc
    21901 ccggcggatt cctgatcgcc agcgatgaag gcagcgaact ggttgatcag gcctggccgt
    21961 caacgccgct gtatgactat cccgcgcagg aacagtggag cgccttccag cgtctggcgc
    22021 aaacgctcat gcagacgcca tttagcgccg agggcattgt caccagcgtg tataccgatg
    22081 ccaacggcac gcagcatatc agcctgcatc gtatccccga taaatccggc tggtggcgtt
    22141 acctcggcac cacgctgctg atgctggcaa tgatagtgag cgcggtctac aacggcattc
    22201 aggcgttcag gcgttatcaa cgccaccgta cccgtatggc ggacatccag gaatactatg
    22261 aaagctgcct caatcccagg ttaaccgtct ctccggaaaa tctcatctga tagcgccgcc
    22321 gtgcgacagg gtatgctacc ctgtcgcgca aattgcgtta ccctggagtt ccccatgcat
    22381 attgatattg actggcaaaa cgtggatacc gttttgctgg atatggacgg cacgctgctc
    22441 gatctcgcgt tcgataacta tttctggcaa aagctggtac cggaaaccta cggcgcgcag
    22501 cagggtattt cgccgcagga cgcgcaggaa tatattcgcc agcagtatca tgccgtacag
    22561 catacgctaa actggtactg tctggattac tggagcgagc gtctgggtct ggatatttgc
    22621 gccatgacga cggcgcaagg gccgcgcgcc gttttgcgcg acgataccgt accgtttctg
    22681 aatgcgttaa aagccagcgg aaaacgtcgg attctgctca ccaatgcgca tccacataac
    22741 ctggcggtga agctggagca taccggtctg gcctcacacc ttgatttatt actttccacc
    22801 cacacatttg gttatcccaa agaggatcag cggttatggc gcgctgtcac tgaggaaacg
    22861 ggaataagcg cagagaaaac gctgtttatc gatgacagcg aaccgattct cgacgccgcc
    22921 gcccggtttg gtattcgcta ctgtcttggc gtgacgaatc ccgattccgg tctggcggaa
    22981 aagcactata cgcgccatcc gtccctgaac gactaccgcc gtctgatccc ctcgctgaag
    23041 tgaaggagac gccatgaaag aaaagtcctc cgttgaggtc agactggata aatggctgtg
    23101 ggccgcgcgt ttttataaaa cccgcgcgct ggcccgcgag atgattgaag gcggtaaggt
    23161 gcattacaac ggccagcgca gtaagccgag caaaatcgtc gagctgaacg caacccttac
    23221 cctgcgtcag ggaaatgacg aacggacggt gatcgttaaa gccatcaccg aacagcgccg
    23281 tccggccagc gaagccgtcg ctctgtatga agagacggcg gaaagcgtgg aaaaacgcga
    23341 aaaaatggcg caggcgcgca agcttaacgc cctgaccatg ccgcatccgg ccaggcgacc
    23401 ggacaagaaa gagcgccgcg acctgttacg atttaaacac ggcgacagcg aataactgtc
    23461 acccgcaaga gagatgatta tgccgcaaca tgaccaatta catcgttatc tgtttgaaaa
    23521 ctttgccgtt cgcggcgagc tggtgaccgt ttcggaaacc ttgcaacaga tcctcgacaa
    23581 tcataactat ccgcagtcgg tgaaaaccgt actggccgaa ctgctggtcg ccactagcct
    23641 gctgaccgcg acgctgaagt ttgccggtga cattacggta cagctccagg gcgacgggcc
    23701 gttaagcctg gcggtgatca atggcaataa tcagcagcag atgcgcggcg tggctcgcgt
    23761 tcagggcgat atccctgaca atgcggatct caaaacgctg gttggcaacg gctatctggt
    23821 gatcaccatt acgccggaag agggtgaacg ctatcagggc gtggtgggtc tggaaggcga
    23881 tactctggcg gcgtgcctgg aagattactt cctgcgctcc gagcagttgc cgacgcgcct
    23941 gtttatccgt accggcgatg tcgacggtaa accggcggca ggtggaatgt tgctccaggt
    24001 gatgccggca cagaacgcgc aggcggagga tttcgaccat ctggccatgt tgacggaaac
    24061 cattaaaagc gaagagctgc tgacattacc ggcaaatgac gtgctgtggc gtttgtatca
    24121 cgaagaagaa gtcacgctct acgatccgca agaggttgaa ttcaaatgca cctgttcacg
    24181 cgaacgttgc gcgggcgcgc tgaaaacatt gccggatgaa gaagtggaca gcattctggc
    24241 ggaagaaggc gaaatcgata tgcactgcga ttactgcggc aatcattacc tgttcaatgc
    24301 gatggatatc gcggagatcc gtaacaacgc ctctcctgcc gatccacagg ttcattaatc
    24361 gcctcgtagt cggcagcgtc attgcctgat ggcgctacgc ttatctggcc tacagcatcc
    24421 cgctccgtag gctggataag gcatttatgc cgccatccgg caaaaagctt actcgttgta
    24481 gtaatccaca tccaaccgct gaccatcaac aatgatatcg cgccaagctt tgggggctga
    24541 gtctaaccga tgcccggcaa tcgcgtgcaa cagttgcgtc ttagaaaacc cgtccggcaa
    24601 tcgggcgaac gctttctgcg tccatttccc ctcttttaag ccgtagacct ggctctcggc
    24661 aacaataaag ttatacagca cctgctcagg ctgaccgtcg ccgttaagat cctgactcac
    24721 cagcacgcag gcatccggtt caaggcagga agcgtccgaa taactctgct ctttgacaaa
    24781 cgcccaaaat gcggcatccg gcttctggct accgggcgca atcatcacca cccgcgctaa
    24841 atcgtccgcc gtcggaggga ccttatttct ctgcaaaaac gtcatcagtt cacgattgcg
    24901 ctttctgttc tgcgtaaacg cctcgtcatc ccgcaacgat ttcagcgctt cctggccagg
    24961 tttgccgctg tgatccagca tatacaggct gatctgatcc gcagtaattt taccgctatg
    25021 gtaacgcgcc atatggctgt tgacgctaat acgccagaca tcaagtacag gcgaggccag
    25081 caacagcaat atcaccagcg tcaacaaaga gacgctcagt atcaccttgc cttgccactc
    25141 atcagggtcg cgtccgcggc gtaacagacc gatcagataa ccgaaggacc ataccagcaa
    25201 gacagacgcc gtcagcgcgc catacagacg atccggcgtc cagccgtatt gctgaatgcg
    25261 tacccataac gcccagcccg ccagcagcat atatatcggg gcaacgcaca gcgaggcgct
    25321 aatcatgccg cgtagtacgc gcggataggg taatacgcgc ttttgcggtt cgttgacaat
    25381 cgccacgagg agcagcagca tcagcgtcag cgtggatagc agccccgtag cggaaacacg
    25441 cgcagaaatc gcctccagtc cggtaaaggg taacgtcaca ataaacagca atgccagcag
    25501 cgacaccact ggcagtaaac ccgtcgcgat cagcgtcagc agcttttgca ccgccgccac
    25561 aaggcgcgac tgcgtgcggg cgagaatgac cgccagcgcc gtaatcaggc cgatggtcac
    25621 ataaataaag gcttcagttt caaagaaaag ggtgctgaaa aagcggatgc ccaccagcct
    25681 gaatagcgcg ctccagagca gaagcaccag ccagaacagt ccgttggcga ccaggacgat
    25741 aaacaatgtc agtacgttat gccataaccg cagataaaac tggggataac gcgccgaacc
    25801 ggtttgcgaa tgtaactgat attgcatcca gggtaatacc agcatcgcca tcaacacaag
    25861 ccggagacca tacagccaga ggagctcggc caggcgccat ttctccaccg cctcaacctg
    25921 ccatttcagc cagccgctca ttgccagcac gaccacaaag atcagcccca gccagcccca
    25981 cagcgcgcgc tgtttaaaag agaccacggt aagcaatagc attgacgaca acgctatcgt
    26041 cgcaggcata ccatagaaca gccagtcgct attttgtggt accagccagg ccatcagcag
    26101 gtagcacaag acgccctgca gcaaaccagt gagcaacata ccccagcgag tagtacgtga
    26161 aagcgctaca ctttccatgt cgttatccag aatgatgaga aagccgcatt attgcaccat
    26221 ctgttcaccg ccaggcgtcg tcatgcataa ttcagaaaaa aacgcagaga ggtgaatcga
    26281 tattgttaat gttggtgtta cgtaactttc ttacatgaat gcgattacag tcacattatg
    26341 tcggtcaaaa acacttcctt ttaacgtttt cagaacattt tccacaacaa aagtaggttt
    26401 cctgccataa taaccgccgc tgcgtgacag gagtcacagt gtttttcgtc aatcgtgatt
    26461 ttgtccagat acgtaaatct atgagccttg tcgcggttaa ccaacctcaa aaaaccttac
    26521 tattttcggt aatatatatt ggctaaggag cagtgatatg cgcgttaaca atttaacccc
    26581 gcaagatctc aaggcttatg gtatcaacga cgtccaggat atcgtttaca atcccagcta
    26641 cgacaccctt tatcaggaag aacttaatcc tggtctggaa ggctatgagc gtggcgtgtt
    26701 aactaacctg ggcgctgttg ccgttgatac cggtattttt accggtcgtt cgcctaagga
    26761 taagtatatt gttcgcgacg acaccacgcg tgatacgctg tggtggtccg ataagggtaa
    26821 aggtaaaaac gataataagc cgctttccca ggaaacctgg caacacctga aaggtctggt
    26881 gacgcatcag ctttccggta aacgcttatt cattgttgat gcgttctgcg gcgcaaatgc
    26941 cgatacgcgt ctttccgtgc gctttattac ggaagtcgcc tggcaggccc acttcgttaa
    27001 aaatatgttc attcgcccaa cggacgaaga gctggtaggc ttcaaacctg actttattgt
    27061 catgaacggc gcgaagtgca ccaacccgca gtggaaagag caagggctga actcggaaaa
    27121 cttcgtggcg ttcaacctga ctgaacgtat tcagcttatt ggcggcacct ggtacggcgg
    27181 cgaaatgaaa aaagggatgt tctcggtaat gaactacctg ctgccgctca aaggtatcgc
    27241 ctcaatgcac tgttccgcca acgtgggtga aaaaggcgat gtcgcggtct tcttcggcct
    27301 ttccggtacc ggaaaaacca ctctgtccac cgacccgaaa cgtcgtctga ttggcgatga
    27361 tgagcacggt tgggatgacg acggcgtgtt caactttgaa ggcggctgct acgccaaaac
    27421 catcaaactg tcgaaagaag cggagccaga aatttatcat gcgattcgcc gtgatgcgct
    27481 actggaaaac gtcaccgtgc gcgaagacgg caccgtagat ttcgacgatg gttccaaaac
    27541 cgaaaacacc cgcgtctctt acccgatcta tcatatcgat aacatcgtta agcccgtatc
    27601 caaagcaggt cacgccacca aggttatctt cctgacggcg gatgctttcg gcgtgttgcc
    27661 gccggtttcc cgtttaaccg ctaaccagac gcagtaccac ttcctgtcgg gtttcaccgc
    27721 taaactggcc ggcaccgaac gcggcgtcac cgaaccgacc cccaccttct ccgcctgctt
    27781 cggcgccgcg ttcctgacgc tgcacccgac gcagtatgct gaggtgctgg tgaaacgtat
    27841 gcaggcagca ggcgcacagg cttatctggt taacaccggc tggaatggca ccggcaaacg
    27901 tatctccatc aaagatacgc gcgcgattat tgacgctatt ctgaacggtt ctcttgataa
    27961 cgcggaaacc ttccgcctgc cgctgttcga tctggcgatc ccgactgaac tgccaggcgt
    28021 ggatacccac attctcgacc cacgtaacac ctacgcgtcg ccggaacaat ggcaggaaaa
    28081 agccaccgcg ctggcgaaac tgttcattga gaacttcgag aagtatacgg ataccccggc
    28141 aggcgaagcg ctggttagcg ccggaccgaa gctgtaagga acaggccgga tggcggcttt
    28201 gaacagcgtc atccagtgtt aagaagaaag ggagggtaat acctcccttt cttatgcctc
    28261 ttttgtcgtc ccctggacgc gagccacagg aaccggtagc caggcgcgaa tcgacaatcc
    28321 gccacgctcg ctggtgccaa tctccagcat cccgttatgg ttatcaataa tgcgctgcac
    28381 aatcgccagc cccagccctg tgccgctggt gctacgggcg ctgtcgccgc gcacaaaagg
    28441 ctggaacaga tgtttacgct gctccggctt aatgcccggc ccgtcatctt ctacctggaa
    28501 ccaggcgcga tgcgactcgg tgccgctgct gaccttaatc cagcagttgc catagcgggc
    28561 agcattgacc accatattcg ccaccgcgcg cttaatcgag agcgggtgca ttttcacctg
    28621 gatgctgcct gcctgaagcg cagtgttaat ctcacgctca tagccgcttt ccgccgcaat
    28681 cacctcgccc agcacggaat tgagatccgc catctccatt ggcatttcct gaccggtacg
    28741 cagatagtca ataaactgtt cgataatggc gttacactct tcgatgtctt tattgatcga
    28801 ctccgcgaga taaccgtctt cctcgcccat catctccgtc gccagacgaa tacgggtcag
    28861 cggcgtgcgt aagtcgtggc tgacgcccgc catcaatagc gtacggtcat cggccaattg
    28921 tttcacgccg gctgccatat ggttaaacgc ccgggtcaca gagcgcacct cagaggcgcc
    28981 atattcacgc agcggcggcg gaataattcc cttccctacc tgcaaggcgg catgttcaag
    29041 atccactaac ggtctgttct gtatacgaat aaacagccac gcgccgccta tcgccaggag
    29101 catgatcgcc agcgtgtaac ggaaaagcgg agaaaaatcg ccctgatgaa tctcggtcag
    29161 cggcacgcgc acccagatat tgggcgacag ccaggttttg agccacacga cgggcgagct
    29221 tttgttgacc tcaacccgca cttccgtcgg gccgcctaat tgctgcgcca tctggtggct
    29281 taagaattcg tagtgttgcg cccaacgcag cccggcctct tcagcggctt cgttggtgta
    29341 gagagagatc cccagctcgc gatagatttc ccggcgaaac gcaggcggca cgactaactg
    29401 cgtgccgtcc tccagttgca gcttatcggt catcagcata cggacttcgt aagccagaac
    29461 cttattaaac tgctggaggc tcggcaaaat cgcgaagttc agcaccacca ggtaggtcgt
    29521 caccaggctg acgaacagca aggtgacgat gagcaacagc gtgcgggcaa atgaacttcg
    29581 cggcgagaag cgcattcgcc tcatgcttta gaaccgtccg gtacgaagac gtagcccagg
    29641 ccccatacgg tctgaatata acgcggatgc gccggatctt cttccaccat acggcgcagg
    29701 cgggagatct ggacgtcgat ggagcgttcc atcgcggaat actcgcggcc acgggccaga
    29761 ttcatcagct tgtcgcgaga gagcggctcg cgcggatggc tgactaacgc tttcagtacc
    29821 gcaaactccc cgctggtcag cggcatcggt tcatcttcac ggaacatctc gcgcgtaccg
    29881 aggttcagtt tgaacttacc gaacgcgata acggcctctt cctgcgacgg cgcgccgggc
    29941 agttcgtttg cctgacgacg tagcacggcg cggatacgcg ccaacagctc gcgcgggtta
    30001 aacggtttag gaatgtagtc atcggcgccg atttccagcc cgacgatacg gtcaacctct
    30061 tcacccttcg ccgtgaccat aatgatcggc attggattac tttgactacg caggcgacga
    30121 caaatcgaca gaccatcttc acctggcagc attaaatcca gtaccatgag atggaaagat
    30181 tcacgggtca gcagacgatc catctgctcg gcgttagcga cgcttcgaac ctggaagccc
    30241 tgctcggtca gataacgttc cagtagcgcc cgcagacgca tatcgtcatc aaccaccaga
    30301 atcttataat tctcttgcat tgtctgtact cccaaaggtt cgcaacaaat gtaagtgtgt
    30361 attcttaaaa aagctcacgt gagtcaccag caaattctgg tatgaatttc aggctaaatt
    30421 gttacaaagc atatttaaca gcagcttaaa tatacaatta atcggcaacc ccattattta
    30481 ttctgtcggg acgatcacgt tataccccgt gtgcgcaata tcgacagcaa aggtaaatca
    30541 acgagatgaa aacgcccctg atcacccgcg aagggtacga aacactcaaa caagagctca
    30601 attatctctg gcgtgaagag cgcccggagg tcaccaaaaa agtgacctgg gctgcgagtc
    30661 tgggcgaccg cagcgagaat gccgactatc agtataataa aaagcgcctg cgtgagatcg
    30721 acagacgcgt cagatatctg accaaatgca tggaaaatct caaaatcgtg gattattccc
    30781 cgcagcagga gggcaaagtc ttcttcggcg cctgggtgga aatcgaaaat gatgacggcg
    30841 atacgctgaa gttccgcatt gtcggctacg atgaaatttt cggacgtaag gattacatct
    30901 ctatcgactc gccgatggcg cgggcgctac tgaaaaaaga agtgggcgat ctggcggtgg
    30961 tcaacacccc tgtcggcgaa gcaaactggt acgtcaatgc gatcgaatac gtcaaataag
    31021 acaagaagaa tcctaagccc ccgctgatgg ctggcatttt tgccagccaa tccgtataac
    31081 tatcccctga tttttatcct gaagacgaag ctaacccatg atgaatgatt ctttctgccg
    31141 cattattgcg ggtgaaatcc aggcaaatgc cgggcaggtt gaagctgccg ttcgcctgct
    31201 tgacgaaggg aacaccgtgc cgtttatcgc acgttatcgt aaagaaatca ccggcggtct
    31261 ggatgacacg cagttgcgta acctggaaac gcgtctgggc tatctgcgtg agctggaaga
    31321 caggcgtcag gccatcctca agtccatttc cgaacaaggc aaactgaccg atgagctggc
    31381 tggcgccatc aacgctacgt taagtaagac cgagctcgaa gacctctacc tgccctataa
    31441 acctaaacgc cgcacccgtg gacaaatcgc cattgaagcc ggccttgagc cgctggccga
    31501 tctgctctgg aacgaaccgt cccacgatcc tgacgtgaaa gcggcaaagt acattgatgg
    31561 cgacaaaggc gtggcggaca cgaaagccgc gctcgacggc gcacgctaca ttctgatgga
    31621 gcgctttgcc gaagacgccg cattgctggc gaaagtgcgt gattacctgt ggaagaatgc
    31681 ccatctggtc gccacagtcg tgagcggcaa agaggaagaa ggggcaaaat tccgcgacta
    31741 tttcgaccat catgagccca ttgctaacgt cccgtctcac cgtgcgctgg ccatgttccg
    31801 tggtcgtaac gaaggcattc tgcaactttc gctcaatgcc gacccacagt ttgatgagcc
    31861 gccgaaagag agctactgcg agcaaatcat catggaccat ctcggcctgc ggctaaataa
    31921 cgccccggcg gatagctggc gcaaaggcgt agtgagctgg acgtggcgta tcaaagtctt
    31981 aatgcacctc gaaaccgaac tgatgggcac cgtgcgcgaa cgtgcggaag acgaagcgat
    32041 taacgtgttt gcgcgtaacc tgcacgacct gctgatggca gcccccgcag gcctgcgcgc
    32101 cacgatgggc cttgatcctg gcctgcgtac cggcgtaaaa gtcgctgtcg ttgacggcac
    32161 cggcaagctg gtggcgacgg ataccattta tccgcatacc ggtcaggcgg ccaaagcggc
    32221 taccgtgatc gccgcgctgt gcgaaaaata ccacgtcgaa ctggtcgcga ttggcaacgg
    32281 tacggcttcg cgtgaaaccg aacgtttcta tctcgacgta cagaaacagt tcccgaacgt
    32341 gacggcgcag aaagtgatcg tcagcgaagc gggggcgtcc gtgtattccg cttctgagct
    32401 ggcggcgcag gagtttccgg atctcgacgt ctccctgcgc ggcgcggtct ctatcgcgcg
    32461 tcgtctgcag gatccgctgg cggaactggt gaaaatcgat ccgaaatcga tcggcgtcgg
    32521 ccaatatcaa cacgatgtca gccagaccca attggcccgt aaactggatg cggtggtcga
    32581 agactgcgta aacgccgtcg gcgtcgattt gaataccgcc tccgtaccgc tgctgacccg
    32641 cgtcgcaggc ttaacgcgca tgatggcgca aaacatcgtc gcctggcgcg atgagaacgg
    32701 tcagttccag aaccgccagc aactgttgaa ggtgagccgt ctggggccga aagcgtttga
    32761 gcagtgcgcg ggcttcctgc gtattaacca cggcgataac ccgctggatg cctccaccgt
    32821 ccacccggaa gcctatccgg ttgtcgaacg cattctggcg gcgacgcagc aagcgctaaa
    32881 agatctgatg ggcaacagca acgaattgcg tcacctcaag gccgctgatt ttaccgacga
    32941 taaattcggc gtgccgaccg tgagcgatat catcaaagag ctggaaaaac cgggccgcga
    33001 cccgcgtcct gaatttaaaa ccgcgcaatt cgccgatggc gtcgaaacca tgaacgacct
    33061 gctgccgggg atgattctgg aaggggcagt cactaacgtc actaacttcg gcgcgtttgt
    33121 cgatatcggc gttcatcagg atggcctggt ccacatctct tccctgtcga ctaagttcgt
    33181 cgacgatcca cacaccgtgg taaaagctgg cgacatcgtg aaggtgaaag tgctggaagt
    33241 ggatctgcaa cgtaagcgta ttgcgctgac gatgcgtctg gacgaacagc ccggcgaaac
    33301 cgccgctcgc cgcggcggcg gtgccgatcg cgctcagggc aaccgcccgg cgtcaaaagc
    33361 ggcgaaaccg cgcggtcgtg acgcccagcc agccggtaac agcgccatga tggacgcgct
    33421 ggcagcggca atgggaaaaa aacgctaatc gggtaatacg caggccgggt tacttcttat
    33481 ccggcctgcg attttgcaat acgtccaacc ctttcttttt taattaacaa ttaaatctta
    33541 cccattagaa tctgttaatt aatttccttc tgctatccgc actattaatt atcactttat
    33601 taacagatga aaccttaatt aaacattaaa aacggtgaat atttgcacat tagaggtatt
    33661 tgcaaaaaga caaataaatg ttgagccata tcaacatcgg cgcaaattat cgcttatttg
    33721 tacattccgt cacattttaa tcgttgaaga tagaaaccat tctcattatc attgtgttgt
    33781 tgattattta ctctttcctt cgttggctaa acatcgggtc tcctgccgcc cccctgagcg
    33841 ccgcatgagg tatacatcca gttagtaaga aacaagtagg tcgtatgcaa ttcactcctg
    33901 acactgcgtg gaaaatcacc ggctttgcgc gtgaaatcag cccggcgtat cgtcaaaaac
    33961 tgctttcgct cggcatgttg cccggctctt catttaatgt tgtccgcgtc gcgcccttag
    34021 gggatccgat ccatatcgaa acacgacgcg tgagtctggt tttgcgtaaa aaggatttgg
    34081 cgttaataga agtggaagcg gtttcctgtt aatacagtga gtctataaaa atgaaaaaat
    34141 taaccattgg tttaattggt aatcctaatt ccggcaagac caccttattt aaccaactca
    34201 ccggcgcgcg tcagcgcgtg gggaactggg cgggcgtcac cgtcgagcgt aaagagggcc
    34261 agttcgcgac aactgaccac caggtcacgc tggtagattt acccggcacc tattctctga
    34321 cgaccatctc gtcacaaacc tctctcgacg aacagatcgc ctgccactac atcctgagcg
    34381 gcgacgccga cctgttgata aacgttgtgg acgcctccaa tctggagcgc aacctctatt
    34441 tgacgctgca gctgctggag ctgggtatcc cctgtattgt tgcgctcaac atgctggata
    34501 tcgccgaaaa acagcaggtt cgtattgatg tcgacgctct gtccacgcgt ctgggttgcc
    34561 ctgtcgtacc gctggtatcg actcgcggtc gcggtatcga ggcgctgaaa ctggccattg
    34621 atcgtcacaa cgctaacgac aacgtcgaac tggtgcatta tgcccagccg ctgctgcgcg
    34681 aagcgggttt cctggccgac gcgatggccc aggagatgcc tttacaacag cgccgctggc
    34741 tgggtctgca aatgctggag ggcgatatct acagccgggc ttacgcaggc gaggcggcgc
    34801 aaaacctgga cacctccctt gcccgtctga aggacgaaat ggacgacccg gcgctgcata
    34861 tcgccgacgc ccgttaccag tgtatcgccg ctatttgcga cgtggtcagc aataccctga
    34921 cagccgaacc cagccgcttc accagggcgg tcgataaaat tatcctgaac cgcttcctcg
    34981 gcttaccgat ttttttgttc gtgatgtacc tgatgttcct gctcgccatt aacatcggcg
    35041 gcgcgttgca acccctgttt gatgccggtt ccgtcgccat ctttattcat ggcattcaat
    35101 ggattggcta cacgctgcac ttcccggatt ggttaaccat cttcctggcg caaggtcttg
    35161 gcggcgggat caataccgtc ctgccgctgg tgccgcaaat cgggatgatg tacctgttcc
    35221 tctccttcct tgaagactcc ggttatatgg cgcgcgcggc cttcgtcatg gatcgcctga
    35281 tgcaggcgct gggactaccg ggtaaatcct tcgtgccgct gattgtcggc ttcggctgta
    35341 acgtaccttc cgtgatgggc gcccgcacgc ttgacgctcc gcgcgaacgc ctgatgacca
    35401 tcatgatggc gccgtttatg tcctgtggcg cgcgcctggc gattttcgcc gtctttgccg
    35461 ccgccttctt cgggcaaaac ggcgcgctgg cggtcttctc gctatacgtg ctgggtattg
    35521 tcatggcggt attaaccggc ctgatgctga aacataccat tatgcgtggc gaagcctctc
    35581 cgtttgtgat ggagctgccg gtttaccacg taccgcatat caagagcctg atcatccaga
    35641 cctggcaacg cctgaaaggt tttgtactac gcgccggtaa agtcattatc atcgtgagta
    35701 ttttcctgag cgcgtttaac agtttctcgc tgagcggcaa aatcgtcgat aacattaatg
    35761 actccgccct cgcctctgta agccgggtca tcacgccagt ctttaaaccg atcggcgtcc
    35821 atgaggataa ctggcaagct accgtgggtc tgtttacggg cgccatggcg aaagaggttg
    35881 tcgtcggtac gctgaacacg ctctacaccg ccgaaaatat tcaggacgaa gcgtttaatc
    35941 ctgccgactt tcacctcggc gatgaactgc tgggcgcggt tgacgatacc tggcaaagcc
    36001 tgaaagacac ctttagcctg agcgtactgg ctaacccgat cgaagcgagt aaaggcgacg
    36061 gcgaaatggc gaccggcgcg atgggcgtga tggatcaaaa attcggcagc gccgcggcgg
    36121 cgtacagtta cctgattttc gtcctgcttt acgtaccgtg tatctcggta atgggcgcta
    36181 tcgcccgcga gtccagccgc ggctggatga gcttctccat cctgtggggg ctgaatatcg
    36241 cctattcgct cgccacgctg ttctaccagg ttactagctt cagtcagcac ccgacttaca
    36301 gcctgatctg tattctggcg gtaatcgtct ttaacgttgt ggtattaagt ctgctacgcc
    36361 gcgcccgcag ccgtgtagac attgaactgc tggcaacccg caaaagcgtc acatcctgtt
    36421 gttcgggcac tgcgggcaat tgtcactaag ggatgtaaaa aatggcttca ttgatacagg
    36481 ttcgcgatct actggcgctg cgggggcgta tggaggcaac gcagatcagc catacgctgc
    36541 acgctccgca gcccatgatc gacgccatgc tgaatcaact ggagatcatg ggtaaagcgg
    36601 tacgtatccc ggaagaaccg gacggttgcc tttcaggcag ttgtaaaagc tgtccggaag
    36661 gtaaagcctg cctgcgcgaa tggtgggcct tgcgttgacc ttcgccgggt agcgacgtaa
    36721 cgcgtcttat ccggccttta tcccgcgtta tattgcccgg tacgcgtcac gctgccgggc
    36781 aattttgcgt catgccttcc acaaagatga aagcgttacc gccgtgcgca tttatctccc
    36841 cacgcgcctc gcaagcgcac taatcctcta ctgcaatcag cccggtctgc gcgtagtgtc
    36901 acgccattga gcttcaccgg tgacggatcg atatggcgac ctcaacaaca tccacgccgc
    36961 atgacgcggt attcaaacag tttttatgcc accccgatac tgcacgggat tttttggaaa
    37021 tccatcttcc gtcgacatta cgtcaaatct gtaatctgaa tacgttacgg ctggagtccg
    37081 gtagctttat tgaagaggat ttacgccccc attattccga tatcctttgg tcgctggaaa
    37141 caagtgaagg tgacggttac atttacgtgg ttattgaaca tcagagtacg ccggacgcgc
    37201 atatggcatt tcggctgatg cgttacgcaa tggctgcaat gcaacggcac ctggaggccg
    37261 ggcataagac gttgccatta gtggtgccaa tgctgtttta ccacggaaac cgaagcccgt
    37321 atccgttctc attatgctgg ctggatgaat ttgccgaccc ggtgatggcg cgtaagctat
    37381 acgccaccgc ctttcctctg gtcgatatta cggtcgtgcc ggacgacgag attatgcggc
    37441 accgacgggt cgcgctgctg gaactcatac aaaaacacat ccgccagcgt gatctgatgg
    37501 ggcttgtcga acagctggtc gccctgctgg ttaagggata cgctaatgac acccagcttc
    37561 aaagtctgtt taattacatg atgcacactg gcgacgccgc gcgcttcaat acgtttatcc
    37621 gccaggtggc tatgcgtatc ccacagcata aggagaagat catgactatc gcagaaagat
    37681 tacgtcagga aggacatcgt aacgggttac agaaagggct acaacaaggc aaacaggaag
    37741 gccaacggct cgccgcattg cgcattgccc gctccatgct aaacgatggt ttcgatcgcg
    37801 atactgtgct tagggttacc gggctggcgc ctgccgatct ggcgtctgaa agccattaat
    37861 ctggcagaat ggcctgggcc cggcaacgcc ctggttacag cgatgatttt agcgtcatca
    37921 gcgcctggca aaacgccgcc ggatgcgaga taaacggcgc atgggccgcc ttcgccatta
    37981 tctgtgatgt actgtgcggc cataacgtat cgagcaaagg cgcgatttta cgcggcacca
    38041 gaccgtccag ataaccatac aaacgcaaaa acggcatgtt cacattttta agcgcttctc
    38101 gtagatcgac cgtttttaag atttccagtc cgccattgag cacctctaca tccggcatag
    38161 gctgcgccag cactacgctt tttaaggtgc gggcatcctg acgcgccgtc tccgtcccta
    38221 acgtttgcag cgccagaaaa cgctccaccg tgcgctgaaa atcgtcgcta agctgctgct
    38281 ggaatccgcc gaggatttct ggttttattc ccggccaccc ctcacgcgcg ctaaagcatg
    38341 gcgaagaggc gactgtcacc agcgcctgaa cgcgttcagg gtgggtgagc gccatctgac
    38401 tcgccaccag gccgcccaga ctccagccaa gccagatagc ctggtccggc gcgtttttcg
    38461 ctacctgcgc cgtcatctct tcaagcgtca tggcaccaaa ccccgaacta cggccatagc
    38521 ccggcaagtc gaccagatgc agcgtaaaat gcgagccgag ttcctcgcga atgcaatgcc
    38581 acacctccgc gttcaatccc catccgtgca gcagcacaag atgacaattt ccctcgccgt
    38641 aggtctgcca ccagatgtca ttcatcagtt actgttctct tttgtctaac aaggatgcac
    38701 ctatgctaac agtaccggga ttatgctggc tatgccgaat gccgctggcg ttaagccact
    38761 gggggatttg ctccgtatgc gcgcgcgccg ttcgtcagcg cgtcagcctg tgtccgcaat
    38821 gcggattacc tgccgggcat ccttcgctcc cctgcggtcg ctgcctgcaa aaaccgccgc
    38881 cctggcagcg tctggtgagc gtcagtgact atacgccgcc cttgagttta ctggtgcatc
    38941 agcttaaatt tacccgccgc agcgaaattg ccgccgctct ggcgcgtcta ctgttgcagg
    39001 aagtacttat ggcgcgccgc agcactggct tgccgcttcc cgacagaatc gtcagcgttc
    39061 cgctctggtc gcgccgacac tggcggcggg gatttaacca aagcgatctg ttatgccaac
    39121 cgttagcgca ctggctgggc tgcgcgtggg acagccagac catcacgcgg gtacgggcga
    39181 ccgcaacaca acatcatctc agcgccaggt tacgtaagcg caatttgaaa aacgcgtttc
    39241 gccttgaatt gccggtacag ggtctccata tggttattgt ggatgatgtc gtcactaccg
    39301 gaagtaccgt cgcggaaatc gcgcaactgc ttttgcgcaa cggcgcagcg actgtccagg
    39361 tatggtgcct gtgtcgaacc ttgtagagcc tcgatgacgg gcgtattata accaactaaa
    39421 atagtcaact attaggccat tactatgatc cgtatttccg atgctgcaca agcgcacttt
    39481 gccaaactgc tggcaaatca gaaagaaggg acgcaaatcc gcgtatttgt cattaatccc
    39541 ggcactccta acgcagagtg cggcgtttct tattgtccgc ccgacgccgt agaagccacc
    39601 gatactgcac tgaaatttga cctgttgacc gcttatgtcg acgagctgag cgcgccctat
    39661 ctggaagacg cggaaattga tttcgtgacc gaccagctag gttctcaact cacattgaaa
    39721 gcgccaaacg cgaagatgcg caaagtggcc gatgacgcgc cgctgatgga gcgcgtggaa
    39781 tatgctctgc aatcgcagat taacccgcag ttggcgggcc acggcggtcg cgtctcgctg
    39841 atggaaatta ccgatgaagg ctatgcaatt ctgcagtttg gcggcggttg taacggttgc
    39901 tcgatggttg acgtcacgct gaaagaaggg atcgagaaac agttgctgaa tgaattcccg
    39961 gaactgaaag gggttcgcga tctgaccgaa caccagcgcg gcgagcactc atactactaa
    40021 gattttcccc gcatccatgc ccgatggcgc ttgcgcctgt cgggccttgt ctgccccacc
    40081 gtaggccgaa taaggcgtct acgccgccat tctgcgccat cagccacatc tcagaacaat
    40141 ggttcttctt ctttcgccga taacatgacc tgtgtctcat aatttaaatt ttgcctgcca
    40201 gggtcatttt caacacccat atgttacccg tatcattctt atgggcacct aacatccata
    40261 taacatctga ctacgctcat tcgtttcaac ggtaatcagt attggtgcta ttgcgactct
    40321 gttcccgtcg ggaacaacag gaatttgtcg tcgaaacaat gacgttaccc ataacaaagt
    40381 aaaggccagg taaatcatgc cattagtcat cgttgctatc ggtgttatct tgttacttct
    40441 tctgatgatc cgcttcaaaa tgaacggatt tatcgccctt gtcctggtag cgctcgctgt
    40501 cgggttgatg cagggaatgc cgctggataa agtcatcggc tccatcaaag ccggtgtcgg
    40561 cggtacgctt ggcagtctgg ccctgattat ggggttcggc gccatgctgg gcaaaatgct
    40621 tgccgactgc ggcggcgctc aacgtatcgc cactaccctg atcgcgaaat ttggtaaaaa
    40681 gcatattcag tgggccgtag tgttaaccgg ctttaccgtc ggcttcgctc tgttctatga
    40741 agtgggcttc gttctgatgc tgccgctggt attcaccatt gccgcagcgg cgaatatccc
    40801 gttactgtac gtcggcgtgc cgatggccgc ggcgctctcc gtcacacacg gcttcctgcc
    40861 gccgcacccg ggtccaaccg cgatcgccac gattttccat gccgatatgg gtaaaacgct
    40921 gctgtttggt acgattctgg cgatcccgac cgtgatcctt gccggaccgg tttacgcccg
    40981 ttttctgaaa ggcatcgata agccgatccc ggaaggcctg tacagcgcga aaacctttac
    41041 ggaagaagag atgccgggct ttggcgtcag cgtctggacg tcgctggttc cggtgattct
    41101 gatggcgatg cgtgcggttg ccgagatgat tctgccaaaa ggccacgctt tcctgcccgt
    41161 tgccgagttc ctgggcgacc cggtaatggc tacgttgatt gccgtactga ttgcaatgtt
    41221 cacctttggc ctgaaccgcg ggcgttcaat ggatcagatt aacgatacgc tggtctcttc
    41281 catcaaaatt atcgccatga tgctgctgat catcggcggc ggcggcgcgt tcaagcaggt
    41341 gctggtcgat agcggcgtgg ataaatacat cgcttcaatg atgcatgaaa ccaatgtctc
    41401 tccgctgttg atggcgtggt ctatcgcggc ggtgctgcgt atcgcgctgg gctctgcgac
    41461 tgtcgcggcg attaccgcag gcggcattgc ggcgccactg atcgccacga ccggcgttag
    41521 tcctgaactg atggttatcg cagtcggttc cgggagcgtg attttctctc acgtcaacga
    41581 cccaggcttc tggctgttca aagagtattt caatttgact atcggcgaga ccattaaatc
    41641 ctggtcgatg ctggaaacga tcatctccgt ctgcggcctg atcggctgtc tgctactggg
    41701 tatggtggtt taagcgaggc ggtttgcagg ccggataagg cagcaatgtg cgccagaatt
    41761 gcctgatggc gctgcgctta tcaggcctac gtgctctcac catcataaag ccggggaaat
    41821 ccccggcttt attacttctt cttcttcgcg gccgcttttc ggcgcttatc caaatcctta
    41881 atcagcttgt ttacgccctc atcggcaaac atagcctcaa gagatgcaga caatttccgc
    41941 cgccagtttt tatactgatc gctggtgccc ggtacgttaa ccggatcggc catatccagc
    42001 cagtcctccg gctgaagccc caacagaccg ctgttactgt cggcgatata gcgctgaagt
    42061 ccgcgattta gcgttggcgt catcgacatt aacaatgcct tatgcccggc gcgttttggc
    42121 agacagccat atttatgcag cgcgtccaat agcccctgtt tcgcccgctc gcgatcctca
    42181 tacagcccgc gcagaatcac ttcatccgga taaagcccca gagctttacc caacgtcagg
    42241 tcaccgcatt cccaatagcc gcgcagcgtg gggagatcgt gcgtcgaggc gacagccatc
    42301 gattgttgcg gatatgcgcc tggcgcgcgg aagtttttct caaggtcatt ttcaaaccac
    42361 agcactttat aagaatagac cccgctatcg cgcagcttgc cgacaatctc aactggcacc
    42421 gtccccagat cttcgcctat caccatacag cggtgacgtt ggctctccag cgccagaata
    42481 gaaagcaaat catctaccgg ataatggacg taagccccct gatccgctgt ttcgtcatac
    42541 ggtatccacc acaggcgcag caacgacatg acatggtcaa tgcgcaacgc gccgcagttt
    42601 tgcatattgg cgcgcagcag gtcgataaag ggctcatacg cccgggcgac aatgatatgc
    42661 gggtccatcg gcggcagccc ccagttctga ccgagcgggc cgaggatatc cggcggcgcg
    42721 ccgacagatg ctttcaggca gtacagctcc cggtcgcacc aggtttccgc gccgccttcc
    42781 gctacgccaa ccgccagatc gcggtacaga ccaatcggta gtttaaaact ctggcaggta
    42841 tcccagcagg cggcgaattg gcgccaggcc agccactgaa gccagagata aaactccacc
    42901 tcttcgcggt gcgcttcaca gaattgtttt acagcgggag actctaccga ctggtacgcc
    42961 tccggccagg ctggccagcc ccagcgctgc ccatcctctt tcacctgata cgcatgcagc
    43021 gcgtcgaatg ccgcctgcca gtaaaggctt tcgccttcgc gggcgataaa gtgacgaaac
    43081 tccgccattt gcgcatcgtc gcgagcggca aaccgcgtcc acgccatccg cagcgccgtg
    43141 attttcagcg cggtaacggt agcgtaatcc acccattgcg catcgcgcgc ctgtcgcagc
    43201 ttttgctgtg tggcgggcat ttgccaccat gcctgcgcct cttcgctcag gcggaaatct
    43261 tcgacggcgt tgacgtcgat atatatcacg ttcagccagc gacgagacga ggggctgtag
    43321 ggactggcgc tctccggatt cgccggataa agcgcgtgga tcgggttcag gccgataaac
    43381 gcgccgccgc gtgtcgccac gtcgaccagc atcgacttca aatcgccgaa atcgccaata
    43441 ccccagtttt tttctgaacg cagagtataa agctggacgc aggcccccca cagttttttc
    43501 ccctccagca gcgcctgcgg ctcatagcat cgcggcgggg caacgataat acggcagtgc
    43561 gtacgctgtt catcctgggt caacgtcagg gtgtggtagc cctccggcaa cgtagccggc
    43621 aggttaagtt ttttaccgcc cgtcacgcgc cctttgtaat gctcgccctc ttccgtagtc
    43681 agcagccagg caaactcacc gcgcccctct accggcaacg ccattttttt acccgcggta
    43741 taaaccttca cattcggcac gaccgcctgt ggtcctgttg tcgtgccgtg catcgccgcc
    43801 agcaaacgtc tcttggtttc agcgccaata gactgcggtt tgccatgagc attgatgtaa
    43861 ctggggctga tccccgccgc cagcgcggca ctatcgagac gtttattttc catcgcgctc
    43921 ccttagcgtt ttgcctgcca gatacgggcc tgataatcgc gaatagagcg atcggaactg
    43981 aacataccgc agcgcgcggt attgaggatc gcggcgcgcg tccacgcttc ctggtcgcga
    44041 tacagcgcat ccacctgctt ttgcgcctcg acataagcgg cgaagtccgc catgaccagg
    44101 tacggatcgc ccccctgttt gccgaggcta tgcagcatct ggtcaaaggc atgtttatcg
    44161 ccatcgctgt attgaccgct ttccagctct tttagtaccg catccagcac tttgtctttt
    44221 ttacgccatt tcaccggatc gtagcctttg gctttgagcg ccttgacctc ttccacagta
    44281 tggccaaaga taaagatatt ctcttcaccc accttttcag cgatttcaac gttagcgccg
    44341 tccagcgttc ccactgtcaa cgccccgttc agcgccagtt tcatgttgcc ggtgccggac
    44401 gcctctttcc cggcagtaga aatttgctcg gaaatatccg ccgccggaat gagcatttcc
    44461 gccgccgaga cgcagtaatc cggcaggaaa accaccttca gcttgtcacc caccgccggg
    44521 tcgttattaa tggcttccgc aaccttattg atagcaaaaa tgatgttctt cgccaggtaa
    44581 tagcccggcg ccgccttcgc gccaaacagg aatacgcgcg gtacgcggtc agcctgcggg
    44641 ttttcgcgga tctctttgta cagcgccaga atatgcaaca gattcagatg ctgacgcttg
    44701 tactcgtgca ggcgtttgat ctgaatatca aaaatcgcat ggctcgaaat ctcaatcccg
    44761 gtacgggcct ggatgaattt caccagccgt tctttgttcg cccgtttgat gtcgcgatat
    44821 tgttgacgga atgtggcgtc gtcagcgtat ttttcgaggt tgatcaactg gtcgagatcg
    44881 ttagcccact cttttttcag cgttttatcc agcaacgccg caagctgcgg attgcactgt
    44941 ttaatccagc gacgcggtgt aatgccgttg gtgacattgt ggaatttgtt cggccaaagc
    45001 tggtgatatt ccgggaacag atctttcacc accagatcgg agtgcagcgc cgccacaccg
    45061 ttgaccgcaa agccgctgac cacgcacata ttggccatgc gcacctgacg gtcatgcacc
    45121 accgccagtt ttgcccatac ctgcttatcg ccaggccagg tgttatcgac cagcgcctta
    45181 aagcgatcgt taatctgctt gataatctgc atatgacgcg gcaacagcgc tttgattaac
    45241 ctctcatccc agcactccag cgcttctggc atcagggtgt ggttggtgta ggcgaaggtt
    45301 ttgctggtga tagcccaggc gtcatcccag ctcatctggt gttcatccag caatacgcgc
    45361 agcagttcag ggatggcaat agtcgggtgg gtatcattta gctgaatgac ctcataatcc
    45421 gccagctcat gcagcttgcg tccggccaga tgatggcggc gcagaatatc cgctaccgag
    45481 caggcgcact ggaagtattg ctgcatcagg cgcagttttt tgcccgccgt gtggttatcg
    45541 ttgggataaa gcaccttcgt cagtttttcc gcatcgatac cctgctgttc cgcccgcagg
    45601 aaagcgccgt cgttgaattt ggtcagatca aacggatgcg cgtgggtcgc ctgccacaaa
    45661 cgcagcggtt gcgcgacgcc gttacgatag cctaacaccg gcagatccca ggactggcct
    45721 gtaatcacaa aacctggttt ccagcgccct tctttggtga ctttaccgcc gattccaacc
    45781 tggacgtcca gcgcctcgtt gtggcggaac cacggatagc tgccgcgatg ccagtcatcc
    45841 ggcgcttcca tctgcttgcc ttcaacaaat gactgacgga acagcccata ctggtagttc
    45901 agaccatagc ccgtagcgga ctgcccgacg gtggccatcg aatcgaggaa gcaggcggcc
    45961 agacgtccca gaccaccgtt gccgagcgcc ggatcgactt cctcttccag cagatcggtc
    46021 agattaatat cgtgcgcttt cagcacatcg ctaacgtcct ggtaccaccc cagatttaac
    46081 aggttatttc ccgtcaggcg gccaatcaaa aattccatcg aaatgtagtt cacatgacgc
    46141 tggcctttcg tcggctgcgc taccggttgc gcgctcagta attccgccag cgcgccgcta
    46201 acggcctgcc accactgacg aggcgtcatg tcggacgccg acagtaaacc gaaacgctgc
    46261 cactgacgcg tcagggcggc ctggaattga tctttattga aggttggctg tgacatagga
    46321 aatccgtcct cgggtaataa aacaacgtta tcgctagttt gccaggctcg atgttgacct
    46381 tcctcctccc ggcactgatt agggagggag gaggagcggg gatgagcata aaagtgtgat
    46441 cgccgccact tacccctgta taaacgcgcc gattcctgtc aacgacaccc agtgttacgc
    46501 ataatcaaat gaataaacag aaataacagt aaaccgcgga gggatatttt cgaagattat
    46561 atgaacgcca aaatagttta ttacctgaaa tattcagcgg cgggaggttc actaacttaa
    46621 cataattaat taaacgcctg gtatcgccat tgtgttaaat ccgcatcctg tccaggacat
    46681 tatttacaat aacggaaata tgacctcagc ccagctctga cgctcgtttc aaccgcgccg
    46741 aatacttttt taataccgtt atttagaatt gtgacagagt gcaaattcag acacataaaa
    46801 agtctgctta gcttgcatta aaatgctttc tggccgacct tatatctatt aattacgaag
    46861 cgcaaaaaaa aatcgcagtt cccccatttc ccacagtgaa gtgattgcta tgttgattcc
    46921 gtctaaatta agtcgtccgg ttcgtctcga ccataccgtg gttcgtgagc ggctgttggc
    46981 taaactttcc ggcgcgaaca atttcaggct cctcctggta accagtcctg ctggctatgg
    47041 gaaaaccacg cttgtctcac agtgggcggc gggcaaaaat gaattaggct ggtactctct
    47101 cgacgaaggc gataaccagc aagagcgatt cgccagttac ttaatcgccg ctatccaaca
    47161 ggccaccggc ggacactgct ctaccagcga agcgatggcg caaaaacgtc agtacgccag
    47221 cctgacgtct ctcttcgcac agctctttat tgaactggcg cagtggcatc gcccgcttta
    47281 tctggtgatt gacgactacc atttgattac caatccggtg attcacgacg cgatgcgctt
    47341 tttcttacgg catcagccgg aaaatttcac cctggtggtg ttatcgcgta atttgccgca
    47401 actgggcatc gctaacctgc gcgtgcgcga tcagctgttg gaaatcggca gccagcagtt
    47461 ggcttttaac catcaggaag caaagcaatt ttttgaccgt cgtctttcgt cgcccattga
    47521 agccgctgag agcagccgca tgtgcgatga tgtggccggt tgggccactg cgctacagtt
    47581 gatcgccctc tccgcgcgcc agaaccatac ctctgcgcat cactccgccc gccgtcttgc
    47641 cgggattaat gccagccacc tttctgatta tctggtggac gaagtactgg ataacgtgga
    47701 tgtcagcacc cgacatttct tacttaaaag cgcgatctta cgctcaatga atgacgcgtt
    47761 gatcgtgcgc gtgaccggcg aagaaaacgg ccagatgcgg ctggaggaga ttgagcgcca
    47821 ggggttattc ctgcaacgca tggacgacac gggcgaatgg tttagctatc acccgttgtt
    47881 tggtagcttt ctgcgccagc gttgccagtg ggaactggcg gcggaactgc cggagatcca
    47941 ccgtgcggcc gcggaaagct ggatggaaca gggttttccc agcgaagcta tacatcatgc
    48001 gctggcggcg ggtgacgcgc aaatgctgcg cgatatcctg cttaaccatg cgtgggggct
    48061 gtttaatcac agtgaactgg cgctgctgga agagtcatta aaagcgctgc cgtgggaaag
    48121 cctgctggaa aatccgcggc tggtgttgtt acaggcctgg ctgatgcaaa gccaacaccg
    48181 ctacagcgaa gtgaatacgc tgctggcgcg cgccgagcaa gagatcaaag gggtcatgga
    48241 cggcacgctg catgctgaat ttaacgcgct gcgcgcccag gtcgccatca acgacggcaa
    48301 tccggaagag gcagagcggc tggcgaaact ggcgctggat gagcttcctc tcgcctggtt
    48361 ttatagccgc attgtcgcga cctccgttca cggcgaagtg ctgcactgta aaggcaatct
    48421 cagccagtct ttatcgctga tgcagcaaac cgaacaaatg gcgcgccatc atgacgtctg
    48481 gcattacgcg ctgtggagct taattcaaca aagcgaaatt cagttcgccc agggattcct
    48541 gcaggccgca tgggaaacgc aggagagagc cttccagttg atcaaagagc aacatctgga
    48601 acaactgccg atgcatgagt ttctggtacg tatccgcgcg caattgctgt gggcgtgggc
    48661 gcgccttgac gaagcggaag cctcggcgcg cagcggtatc gctgtgctgt ccaccttcca
    48721 gccgcaacaa cagttgcagt gcctgacgtt actggtgcag tgctcgctgg cgcgcggcga
    48781 tctggataat gcccgtagtc agcttaaccg actggaaaaa ttattaggca atggtcgtta
    48841 tcactgcgac tggatctcta acgccgataa ggtgcgtgtc atttactggc agttaaccgg
    48901 cgacaagaaa tccgccgcca actggttacg ccatacgcca aaaccggcgt ttgccaataa
    48961 ccattttctg caaggccagt ggcgcaatat cgcccgcgcg cagatcctgc tgggcgaatt
    49021 cgagcctgcg gaaatcgtgc tggaagagtt aaatgagaat gcccgtagcc tgcgcttaat
    49081 gagcgattta aaccgcaatc tgctgttact caatcagctt tactggcaat ccgggcggaa
    49141 aaacgacgcc cagcgcgtat tgcttgatgc cttacagctc gccaaccgca ccggatttat
    49201 cagccatttt gtgattgaag gagaagccat ggcgcaacaa ttgcgtcagc ttatccagct
    49261 caatacgctg ccggagatgg agcagcatcg cgcgcagcgc atcctgcgat atattaacca
    49321 acatcaccgg cataaattcg cccattttga cgaaggcttc gtcgagcgtc tgcttaacca
    49381 tccggatgtc ccggagctta ttcgcaccag cccgctcacc cagcgtgaat ggcaggtgtt
    49441 aggacttatc tattccggtt acagcaacga acagattgcc ggcgaactgg cggtggccgc
    49501 gaccaccatt aagacgcata tccgcaacct ctaccagaaa ctcggcgtcg cgcaccgtca
    49561 ggacgcggta cagcacgcgc agcagttgct gaagatgatg gggtatgggg tttaacgtgt
    49621 gcctgatggc gcttcgctta tcaggcctac catcgcgcgc agagtgtagg cctgataaga
    49681 cagtcttttt agcacagctc taattgaata tggtggtcgg caatcacctg catcacgccc
    49741 ggcggtggta gggtatcggt gtagaccgca tcgaccatac taatgctgcc catgtttacc
    49801 atcgcgttac ggccaaattt agagtgatcc accaccagca tcacgtggcg cgaattttcg
    49861 ataatcgcgc gcttggtgcg tacctcatgg tagtcaaatt ccagcaatga gccgtcgcta
    49921 tcaataccgc taataccgag aatgccgaaa tcgagacgga actgggcgat aaagtcctgc
    49981 gtcgcttcgc caataatgcc gccgtcgcgg ctacggagtt cgccgccggc gaggataata
    50041 cgaaaatcct ctttcgccat tagcgtgttc gctacgttca aattgttggt cacgatccgc
    50101 aaattactgt gccctaacag ggtgtgcgct acggcttccg gcgtcgtgcc gatatcaata
    50161 aacagcgttg aaccattggg gatctgggcc gcgactttgc gagcgatgcg ctctttttct
    50221 tccgtttgcg tcgccttacg atcgtgccac ggcgtgttca ccgagctgga gggcaacgcc
    50281 gcgccgccgt ggtggcgcaa aatcatattc tgttccgcca gatcgttaag atcccgacga
    50341 atggtttgcg ggctgacaga aaaatgctcc accagctctt ccgtactgac gtacccctgt
    50401 tttttcacca gttcaatgat cgcgtcatgc cgttgtgttt gtttcatgaa taatctctga
    50461 aagtaaccaa ccttgcgccg gatagcggca tcgccctacc cggcctggaa aaatatctcg
    50521 accacaggcc ggatacgcct cacgttcgtt ttcgcgcatt cagcgtatca acaaaggcca
    50581 tcgctaaacc gacgataagc ccggcgatgt gcgcgccgtt cgccatagac atgccaaacc
    50641 agtcaaacca accagcaact atccacaata atgcaaaaat aattaagccg cgctggaggt
    50701 aaattccgct ttgcggatcg cgctctccgc gcagccacac gtaccccatc agcgcataga
    50761 cgacgccgga cagcccgcca aaccacgggc cgctaaattt ctgctgtaca tagccgctta
    50821 gcagcgcgct tatcaccgta atgacgatta atttaccgct gcccaggcgc ttctctaccg
    50881 ccccgccgag ataccaccac cacagcaggt taaaaagaat atgcatcagt gagaagtgca
    50941 taaagatatg ggtgaagtag cgccagactt caaattttaa aaccggatcg aacggccacg
    51001 ccagccacac catcaccgtc tgatcgccga tgagactcat cgcgatatag accaccacgc
    51061 aggcgagcat cacgatccag gtaacagggc cggctcgttc acgcagcgtg gcgagaaagg
    51121 gaaaacggcg gtagcgtagc ccgctgttag tctgcccgga ctgccagcta gccgccagat
    51181 aacgcggatc gccgggattt tctataaacc gcgccagctc gacccgcaca cgttcggcct
    51241 gcgattcatc cgccagccag atatcgcttt gattatgttg ctgaatagta agaatgacgc
    51301 cctgggtggc catgtaatca acaaatgcct gcgccacgcg aggattcgca aaggaagtaa
    51361 tcatcaacat tattgctgtc gcttagtcca tacaaaagaa gacagtatat atacccttct
    51421 cgtcggaggc tgcatcttta tgggattacg cgccattcgc gacatcggca gggaaacggc
    51481 gatgccaggc ctcaaacccg ccgtcaatgc tgtaaaccgc atcatagcct tgctggagca
    51541 gatactgcgc ggcgccttta ctactgttgc cgtgatagca cattaccatc acggcggtat
    51601 cgaaaccatg ctcacgcata aacgcgccca gcgtatcgtt agtcaagtga aacgcctgcg
    51661 gcgcatgacc catggcataa ctttgcggat cgcgaatatc gaccagcacc gccgcgccct
    51721 ggtgcagttt ctgatacgcc tcttctacag tgatacattc aaattgttcc atgaatcgct
    51781 ctttcattat tgccggtgaa gccaattaag gcattttatc gcccagtgta cgttgacgga
    51841 gtagcttaac gccataatgt tatacatatc actctaaaat gttttttcga tgttaccaat
    51901 agcgcgtttc tttgctatta tgttcgataa cgaacatttt tgaactttaa cgaaagtgca
    51961 agagggcagc atggaaacca aagatctgat cgtgataggc gggggcatta acggtgcagg
    52021 catcgcggct gatgccgccg gacgcggttt gtccgtactc atgctggaag cgcaggattt
    52081 ggcctgcgca acctcttccg ccagttcgaa acttatccac ggcggcttac gctaccttga
    52141 acactacgag ttccgtctgg tcagcgaagc gctggccgaa cgtgaagtgc tgttgaaaat
    52201 ggcgccgcac atcgccttcc cgatgcgttt tcgtctgccg caccgcccgc acttacgtcc
    52261 agcctggatg atccgtatcg gtctgtttat gtacgatcac ctcggcaaac gtaccagttt
    52321 acccggttcc accggtgtgc ggtttggcgc agattcggta ctcaaacctg aaatcgtgcg
    52381 cggattcgaa tactccgact gctgggtaga cgatgcgcgt ctggtactgg ccaacgcaca
    52441 gatggtggtg cgtaaaggcg gcgaagtcct tacccgtact cgcgcaaccg ccgctcgtcg
    52501 ggaaaatggc ctgtggattg tcgaagcgga agatatcgac accggtaaaa aatatgtctg
    52561 gcaggcgcgc ggactggtta acgccaccgg cccgtgggtc aaacagttct tcgacgaagg
    52621 gatgcacctg ccgtcgccgt atggcatccg cctgatcaaa ggcagccata tcgtcgtgcc
    52681 gcgcgtccat aatcagaaac aggcgtatat tctgcaaaac gaagataagc gtatcgtctt
    52741 tgtcattccg tggatggaag agttttcgat cattggcaca accgatgtcg aatataaagg
    52801 cgatccgaaa gcggtaaaaa ttgaagagag cgaaattaat tacctgttga aggtctataa
    52861 cgcgcacttc cagaaacaac tggggcgcga tgacatcgtc tggacgtact ccggtgtccg
    52921 tccgctgtgc gatgatgagt ccgactcgcc gcaggcgatc actcgcgatt atacccttga
    52981 tatccatgat gaaaacggca aagcgccgct gctttccgtg tttggcggta agctcacgac
    53041 ctaccgtaag ctggccgaac atgcgatgga aaaactggcg tcttattatc caggcatcgg
    53101 gccggcatgg accaaaacgt gcgtactgcc cggcggcgac atcgacggca gccgcgaaga
    53161 ttacgcggcg aagctgcgtc gtcgttatcc gttcctgacg gaatcgctgg cgcgccacta
    53221 ttcgcgcact tacggcagca acacggagtg gattctcggc gaagccacgt cactgcttga
    53281 tttaggcgaa gatttcggtc atgagtttta cgaagcggaa ctcaaatact tggtggatca
    53341 cgaatgggtg cgccgtactg aagacgctat ctggcgtcgc accaaagaag gcatgtggct
    53401 gaccgccgag cagcagtccc gcatcaccca gtggctggcg gcgtatgttg agaaacacca
    53461 actttcactg gcgtcctgag aaaaatgccg gatggcggct aacgcctgat ccggcctaca
    53521 aggatacata aacgtaggcc gggcaagcga agcgccgtcg gcatcgggat ttacaaccgc
    53581 accggatcaa tatgccagat attttcggca tactctttga tggttctgtc cgatgagaag
    53641 tagcccatat tggcaatgtt gagcatcgct ttcgtcgtcc actcttccgg gcgacgatac
    53701 aactcatcca ccttatcctg gcagtccacg tagctgcggt agtccgccag cacctgatag
    53761 tgatcgccaa agttaatcag cgaatctacc agatcgcggt aacggcctgg ctcttccgga
    53821 ttaaagacgc cgttaccaat ctgcgtcagt acctgatgta gctcttcatc tttttcataa
    53881 tagtcgcgag gcttataacc ctgtctgcgc aacgcttcca cctcttctgc agtattaccg
    53941 aagataaaga tattctcctc gccgacatgc tcctgcatct ctacgttcgc gccatccagc
    54001 gtaccaatgg tgagcgcgcc gttcagggca aatttcatat tactggtgcc ggaagcttct
    54061 gtccctgcca gcgaaatctg ctcagacagg tcggcagcgg gaatgatcac ctgcgccaga
    54121 ctgacactgt agttcgggat aaacactact ttcagcttgt cgccaatctg cggatcgttg
    54181 ttaatcactt tcgccacgtc gttgatcaga tgaatgatat gttttgccat gtaataggcg
    54241 gaagccgcct taccggcaaa aatattcacc cgcggcaccc agtcggcctc cggattttct
    54301 ttaatgcggt tatagcgggt aatgacatgc agtacgttca tcaactgccg cttgtattcg
    54361 tgaatacgct taatctgcac gtcgaataac gctttagggt tcaccaccac attcagttgt
    54421 tgcgctatca ctaccgccag ccgcttttta ttttccagct tcgcctgacg caccgcatga
    54481 ttgaccagcg gataatcaca atgctgcttc agctcgctga gctgactaag atcggtacgc
    54541 caggtacgac caatattctc atccagcacg tcagaaagcg gcgggtttgc cagcgccagc
    54601 cagcggcgcg gcgtaacgcc gttcgtgacg ttacaaaaac gggtcgggaa aatcttcgca
    54661 aaatccgcga acagcgactg caccatcagg ttggaatgga gttcagaaac gccgttgact
    54721 ttatggctga ctaccaccgc cagccaggcc atccgtaccc ggcgaccgtt cgactcatca
    54781 ataatcgacg cgcgtccaag caggctggta tcgttgggat attgctcctg caacgttttc
    54841 aggaaatagt cgttaatctc gaagataatc tgcaggtgac ggggcagaat tttccccagc
    54901 atatcgacgg gccaggtttc cagcgcctcg ctcatcaacg tatggttggt ataagagaag
    54961 acctgacagc acacctcaaa cgcgtcgtcc cagctaaatt tatgttcatc aatcagcagg
    55021 cgcatcagct ccggaattga cagcaccgga tgcgtatcat tgaggtgaat ggcgatttta
    55081 tccgccagat tctcataggt tttatgcagt tgataatgac ggtgcaggat atcctgtacc
    55141 gtcgccgaga ccagaaaata ctcctggcgc aggcgtagct cgcgtccgga ataggtggaa
    55201 tcgtccgggt agagcacccg tgaaacgttc tcagagtggt ttttatcttc caccgccgca
    55261 aagtagtcgc cctggttgaa tttaccgagg ttgatttcac tactggcctg cgcattccac
    55321 agccgcagtg tgttagtggc gtcggtgtcg taaccgggga tgatctgatc atacgcgacg
    55381 gccagaatct cttccgtctc aatccagcgc gcttttttac cttcctgctg aatgcgcccg
    55441 ccaaaaagca ccttatagcg cgtattgtgg cgcttgaact cccacgggtt gccatattcc
    55501 agccagtaat ccggagattc tttttgccgc ccgtcgacaa tattctgctt aaacatgccg
    55561 tagtcgtagc gaatgccata cccgcgaccc ggtaatccta gcgtcgccag cgagtccagg
    55621 aagcaagccg ccagccgtcc taagccgccg ttgccaagcc ctgggtcatt ctcttcatcg
    55681 atcagctctt cgagatctaa gcccatggcc tccagcgcgc ctttaacgtc gtcataaatg
    55741 cccagcgaga gcagcgcgtt agagagagta cgaccaatca aaaactccat cgacaggtaa
    55801 taaacctgcc gggtttcctg cgataattgg gctcgattag aacgcagcca gcgctccacc
    55861 agacgatcgc gcaccgcgaa caacgtggcg ttcagccatt cgtgtttatt ggcaatgacc
    55921 gggtctttac caatcgtaaa catcagctta taggcaatag aatgcttaag cgcctcaacg
    55981 ctgagtgtgg gcgatgcata agtaaacgga gcattcatat aaatgattcc tggatgacta
    56041 tttcaagcga tagtacagct cgcggtatga tttcgcggca acttgccagc taaaatccat
    56101 cgccatcgcc tgccgttgta caaaccgcca aagcgaaggc cgtgaccaca acacaaaagc
    56161 acgccgaatc gcgcgtagca acgaccaggc attactgtct tcaaagacaa aaccgctggc
    56221 gataccgtcc gccagatttt ccagcgaact gtcggagacc gtatcggcca accccccggt
    56281 acgccgcacc agaggcagcg tgccatactt taagccatat aactgcgtta agccgcacgg
    56341 ttcgaaacga ctgggcacca gaataacgtc cgcgccgccc ataatgcgat gcgagaaagc
    56401 ttcgtgatag ccgatctgta cgccagcctg ccctgggtgt tccgccgccg ccgcgaggaa
    56461 cccctcctga agcaccggat cgcccgcgcc aagtagcgcc aactggccgc cctgctccag
    56521 cagccccggt aacgcctcca gcaccagatc cagacctttc tggttggtca gacggcttac
    56581 cacggcgaac agcggcactt tgtcgttaac cttcaacccc atcgcaattt gtagctgacg
    56641 tttgttttcc gccttctctt ccagggtatc gcgcgtgtag cgcgacgcca gcagcagatc
    56701 ggattccggg ttccagatct tctcatccac gccgttcagt atgccggaca agcgcccttc
    56761 cagatgacgc tgacgcaaca ggccttccat accataagca aactgcggtt cggtaatttc
    56821 acgcgcatag gtcgggctca ccgccgtaat atggtcggca tagtacaaac cggccttcaa
    56881 aaaggagagt tgtccgttga actccagccc atgcatatta aagaatgacc acggcagctc
    56941 gatgtcatcc atatgctttg cataaaacat gccttgatag gccaggttgt gtacggtaaa
    57001 gaccgatttc gccggccgcc cgcgcgccgc cagataggcg ggcgccagcc cggcgtgcca
    57061 gtcatgggcg tgcaccacgt cggggcgcca gaatggatca agtccgcagg ccatttcaca
    57121 gccgacccac cctaacaggg caaagcgcag cacgttatcg atataggcat ataaattcgt
    57181 atcgtgatag ggactgcctg gacgctcgta cagatgcggc gcgtcgatca gataaatgcc
    57241 cacgccgtta taatgcccga acagcagcga tatcttacct gcgaaagtat cgcggcggct
    57301 caccacatgc gcatcgggta tcccccgacg gatatcggga aacccaggaa gcagaacgcg
    57361 aacatcaaca ccatccgcaa tttgtgccgc aggcaacgcg cctatcacat ccgccagccc
    57421 cccagtcttc agcaggggga acatctctga acatacatgt aaaacctgca ttatcgctcc
    57481 tgtttgacct gcagtttgcg cagcatttca cgcgtgacca gtacaatacc ttcttctgaa
    57541 cggtagaaac gacgagcgtc ctcttccgca ttttcaccaa tcaccatgcc ttccgggata
    57601 atacaggcac ggtcaataac acagcgacgt aaacggcagg agcgccctac ccaaacctca
    57661 ggtaacaaca ctgccgaatc aatattacaa aaagaattta ttctcacccg tgggaagagc
    57721 acagattgca ccaccaccga accagagata atgcagccgc cggagaccag cgagttcagc
    57781 gtcataccgt ggctaccgga gcggtcctgc acgaatttcg caggcggtag cgattccata
    57841 tgcgtacgga taggccagtt ctggtcatac atatccagct ccggcgtcac cgaggctaaa
    57901 tccaggttcg ccttccagta agcttccagc gtacctacat cacgccagta cggttcggct
    57961 tgtggatcgg actgcacgca ggagagcggg aaaggatgcg cgtaagccat accttcgcgg
    58021 gtgattttgg ggataatgtc tttaccgaaa tcgtggctgg aagcgtcatc tttatcgtct
    58081 gccgccaaca attcatacag gtaatcggcg tcaaaaacgt aaatgcccat actggccagc
    58141 gatttgctgg cgtcaccagg cattgcgggg ggattcgccg gtttttcgac aaaatcaata
    58201 atcttgtcgt tttcatcgac cgccatcacg ccgaacgccg tcgcttcttt gatcggcacc
    58261 ggcatacagg ccaccgtgca acgcgcgccc ttttcaacgt gatcgatcaa catacgcgag
    58321 tagtcctgct tgtagatatg atcgcctgcc aggatgacga catattccgc tttatagcaa
    58381 cgaataatat ccaggttctg ggtcaccgcg tctgccgtgc cgcgatacca gttttcgccc
    58441 ttcatacgct gttgggctgg cagcagatcg acaaattcgt tcatctcttc gctaaacagt
    58501 gaccagccgc gctgaatatg ctgcaccagc gtgtgggact gatactgagt gatcacgccg
    58561 atacggcgaa tcccggagtt cagacaatta gataaggcga aatcgatgat gcggaacttc
    58621 ccaccaaagt ggacggctgg tttggcgcgt ttgttcgtta aatcttttag acgcgtgccg
    58681 cggccgccgg ccaggattag ggcaacagat ttcaatggca gctggcgcgc caacattaca
    58741 cgatcgttct tctctaaact caccatgatt aactcctttt ttatcctctc tggaacacac
    58801 acagtccctg ccagaccgcc gttatcaccg gattatcctc tccagcgaat gggggaacgg
    58861 cgcgccattc cccttcgggt aaaactatat ctgtcacctc aagcgtggca tttatcgcaa
    58921 tcagaaaacg gtccgacaac agaatttgca tcagcttagg tccgttttgc cactcatccg
    58981 cactcaaggg ttgcgcgttt ttatttagcc aacgcacgtt gccatcgcct tcttcccacc
    59041 agctattgcc ggttaaagcc ggtatctgct gacgcaaacg aatcagcgcg gcggtaaacg
    59101 tggttaaccc acgatttgcc tgctgccagt ccagccaggt taaggcatta tcctgacagt
    59161 aggcgttatt gttgccgtgc tggctatggc cgtgttcatc gcctgccagc agcatcggcg
    59221 ttccctgaga gagcagtagc gtcgccagca gggcatgaat gctgtcgcgc cgccgctcca
    59281 ttaaatcaag cggaccgcct aatccttctt taccatgatt gtcgctgtaa ttgctgttgg
    59341 tgccgtcgcg attttcctca ccgttcgcct cattgtgttt ctgattgaaa cagacgcagt
    59401 cccggagcgt aaaaccgtca tgcgccgtga gcagattgac agaggcgccg ggcgcgcggc
    59461 cattgcgttt aaacacatcg ctggaagcgg cgaaacgaca ggcaaactcc ccggtcgtca
    59521 ggttacgcgg caaccagaat cggcgggccg catcgcgaaa atgatcgttc cactcggcaa
    59581 acggtggcgg aaaattcccg acctgatagc cgccctcgcc aatatcccac ggttcagcaa
    59641 tcagcttgac cgttgataac acaggacacg ctttaatcgc ggcgaacagc ggcgcatcct
    59701 ggcgaaacgt cggcgtgcgc cccatgacgg acgccaaatc aaaacgaaaa ccatcgacat
    59761 gacaggtttc catccaatag cgcaaacact cgcacgcgta ttccaccacg ccgggatggc
    59821 ttaaattgag cgtgttgccg caccccgtcc agttgtgata atcgccatcg tcccttatcc
    59881 aataatagct acggttatca attccgcgca gggagaaggt tggaccgtcc agatccagct
    59941 cggcgctatg gtttaatacg atgtccagaa tgacctcaat ccccgcgcga tgcagcgctt
    60001 tcaccgcatc gcgaaactcg tccagcgccg tctcgggcga actggcccag gcgggatgca
    60061 gcgcaaacat cgccattggg ttataacccc aataattggt cagccccata cgttgcagac
    60121 gcggctcgct ggcaaactgc gccaccggca acagttccag cgccgtaatg ccaagctgtt
    60181 tgaagtacgc caccatgacc ggatgaccga gcgctttata ggtgccgcgt atctcctggg
    60241 ggagttccgg atgcagatag gtaagccctt tgacatgcgc ttcatagatg accgtttttc
    60301 cccacggcgt gcgcggcgcg gcgtcatctt cccagtcata atggtcgctg attaccacgc
    60361 ttttcggcgc caccgccgcg ttatcgcggt agtccggttc atcgtgtccg ccgtgcaaca
    60421 gcggatgatc ttttagttcg ccctcgactt ggcgcgcata agggtcaagc agtaacttcg
    60481 ccggattaaa ccgatgcccc tgcgctggct gccacgggcc atgtacgcga tagccatagc
    60541 gcaaacctgg cctggcgcct gccagataac catgccagac atcgccgcga cgtcctggca
    60601 ggtcatagcg acgctcattc cctcgggaat caaaaacgca cagctctacg cgctccgcat
    60661 gggcggaaaa gagcgtgaaa ttcacgccat gaccgtcata cgttgcgcca tgcggcgttg
    60721 cttcgccgat cgcaagctgc gtcattcccc ctcccgcatc agccagatcg tcgccaacgg
    60781 cggtaacgtc aggttaagag agtgctgacg gccatggctt tcgatctcat cgctgtgcac
    60841 cacaccgcca ttgccggtgt tgctaccgtg ataatgcatc gaatcagtat tgagaatttc
    60901 acgccagcgt cccggctggt tgatgccaaa gcggtagtcg tggcgaggaa cgggcgtaaa
    60961 gttgctggcg acgatgatct cgttaccggc tttatcacgg cgtacaaaaa tcagtactga
    61021 gcgttcattg tcatcgacca ccagccactc aaagccgtaa gcatcgaaat ccagctcatg
    61081 caacgcttta tggtggcgat aggtgtggtt gagatcgcgc accagacgct gaaccccgtg
    61141 gtgccagtta tcgcccccct ccagcaggtg ccagtcgagg ctggcgtcat ggttccactc
    61201 gcgtccctgg gcaaactcat tccccataaa cagcagtttc ttgccgggga aggcccacat
    61261 ccagccataa taggcgcgca ggttggcgaa tttttgccac gcatcgcccg gcatacgatc
    61321 gagaatggat ttcttgccgt gaaccacctc atcgtgcgac agcggcagaa caaagttttc
    61381 ggtatggttg tacaacatac caaaggtcag cttgtcgtga tgatactggc ggtacaccgg
    61441 gtccagcttc atgtagtcca gcgtgtcgtg catccagccc agattccact tgtaccagaa
    61501 ccccagccca cccgtttccg gtggacgcgt cacgccagag aagtctgtcg actcttccgc
    61561 catgctgacc gcgccgggca cctgctcgcc aataatgcgg ttggtattac gcagaaactc
    61621 aatggcttcc aggttttcac gaccgccgaa ctcgttcggt atccactcgc cctctttgcg
    61681 gctgtagtcg cggtagatca tagaggccac cgcatcgaca cgcagcgcat caatcccaaa
    61741 acgctccatc cagtacaggg cgttacccac cagataatta ctgacttcac gacgaccata
    61801 gttgtagatc agcgtattcc agtcctggtg atagccctcg cgcgggtcgc tatgctcata
    61861 gaggtgggtg ccgtcaaact ccgcgaggct aaattcatcg gacgggaaat ggcccggcac
    61921 ccagtcgaga atgacgttaa ggcccgccgc atgggccgca ttgatgaaat agcggaagtc
    61981 gtcccgcgta ccaaagcggc gggtcggcgc gtagaggccg gtcggctggt agccccaact
    62041 gccgtcaaac ggatgttcgt taaccggcaa gagttcaagg tgcgtaaagc ccatccattt
    62101 ggcgtaaggc acaagctgat ccgccagctc acgatagctc agccagaaat tgttatccgt
    62161 atggcggcgc catgaaccta aatgcacctc ataaatcgag atcggcgcat caaactgatt
    62221 ggctttttgt cgttcttcgc ttggcgtcac tttctccggc agtccgcaaa tcatcgacgc
    62281 cgtttccgga cgcatctgcg cctcaaaagc atagggatcg gctttaatgc gcagattacc
    62341 gttcgcatca agcagctcga atttatacag ttgtccatta tgcgcgccgg ggataaacag
    62401 ctcccaaata ccgctctctt tgcgcagacg catcgggtgg cgacgcccat cccaatagtt
    62461 gaattgcccg acaaccgaaa cgcgacgggc attaggcgcc cagacggaga aacgggtgcc
    62521 ggtgacgcca tccatcgtat cggcgtgcgc gcccagcgtt tcataaggac gcaggtgggt
    62581 gccttccgac aatagccagg catccatttc ctgtattaat ggaccaaaac ggtaaggatc
    62641 gtcgatgagg ttctgctgtc cgtgccaggt cacggcgagc tgatagcgaa agaaattttt
    62701 acgtcggggt aaaacgccgc agaaaaaacc gcgagcgtcg agacattcca gtttgccgac
    62761 tttacgtccg gttttgggtt caatcaccca tacgtcggtg gcgtcaggta atagggcgcg
    62821 gacttctagt ccggcttggg tctggtgcat tccgagtacg gaaaaagggt ccgcaaaatg
    62881 tcctgcaatt agcgcattaa tcacgtctct atcgatacga ctggacatgg tttgttatcc
    62941 tgttttgtgg cgtcactcca tctcactgaa ttcaacatca ggtagtgaca cttctttgac
    63001 ctgaacggcg cagcacactg tgcatcctat ctgcgtcgtc ctaccttcag gttaggctta
    63061 atacccgtgg gattaagcta cccttaaaga atagccaatg ctctgcttaa ctcctgataa
    63121 aaatgaaaca tctgcgttta ctcctgtatt acgcaaaaaa aggtgacgat gcaccctaca
    63181 tatcaatctg acgtctgctt gccgactacg ccttatctgg cggatattgc cggatggcgg
    63241 cgctgacacg ccttatccgg cctacagaac cacacgcagg cccgataagc gctgcaatag
    63301 ccactacgcc aactggcgca gcattcgacg cagcggctcg gcggcgcccc ataacaactg
    63361 gtcgcctacg gtaaacgccg acaagaactc tggccccatg ttcagcttac gcagacgacc
    63421 aaccggcgta gtcaacgtgc cggtcaccgc cgccggggtt aattcgcgca tagtgatatc
    63481 acgatcgttc ggcaccactt tcgcccacgg attatgtgcc gccagcagtt cttccaccgt
    63541 cggaatggat acctcttttt tcagcttaat ggtgaacgcc tggctgtgac agcgcagcgc
    63601 gccgacgcgc acgcacaaac catcaaccgg gatcacagag gcagtattga ggatcttgtt
    63661 ggtttccgcc tggcctttcc actcttcgcg gctttggccg ttatcaagct gtttgtcgat
    63721 ccaggggatc aggcttcccg ccagcggtac gccaaagtta tccaccggca gctcgccgct
    63781 gcgggtcaat gccgtaactt tgcgttcaat atcaagaatt gcggaagacg gcgtcgccag
    63841 ttcatcggcg acatggccat acaactgccc catttgggtt aacagctcgc gcatatggcg
    63901 cgcgccgccg ccggaggcgg cctgataggt cgcgacggat acccagtcaa cgagattatg
    63961 ggcaaagaga ccgcccagcg acatcaacat caggctaacg gtacagttac cgcccacaaa
    64021 ggtcttcacg ccattgttca gtccgtcggt aatcacgtcc tggttgaccg ggtcgagaat
    64081 aataatggca tcatctttca tgcgcagcgt agaagccgcg tcaatccagt aaccctgcca
    64141 tccgctttcg cgcagctttg gataaatttc gttggtataa tcgccgccct ggcaggtcac
    64201 gatgatatcg agcgctttta gcgcatccag atcaaaagcg tcctgtagcg tgccggtgga
    64261 ggtgtcgccg aaggtgggcg ccgcctgtcc aaactgggag gtagaaaaga aaacagggcg
    64321 aatagcgtcg aaatcgcgct cctctaccat gcgttgcatg agaacagagc cgaccattcc
    64381 gcgccagccg ataaaaccaa catttttcat agcgtttttt cctgcaaaga gatgtgctgt
    64441 gtatgcgcgc cagtatcctg tggcgcatcc ttcaccatac aaaaagcagc caaagtcgca
    64501 agtgaaatta atcaatgata gcgaagccat cagtaatgcg acttatcctg ccttaccgcg
    64561 caagcagaaa gtccagtggc gattatcagg gaatttgcgt taggaaggga atcatttccg
    64621 tcgctgtttt attgatccta attatggatc agcgtagaaa tttgcctgct tttatgcgcg
    64681 tactgaaaca tggcgaggca aaatgtcgtt gggcgattgc catgcacacc tcaataaaaa
    64741 aaccgggtag cgattacgcc ttacccggct tacggtatcg atatgtgccc gtttccaggc
    64801 ccggtaagca cagcgccacc gggcaacaag actcagctca gcagttggaa agcaatcatc
    64861 ccgacaatcg cgccgaccgt gccgaggata gtttccatca tcgtccaggt cttcagcgtc
    64921 tgcgcttcgg tcgcgccggt aaatttaccg aacagccaga agccagcgtc gttaacatga
    64981 gaaaccacaa ttgaaccgcc ggcgatacag atagagagcg ccgccatctg cgcgccggag
    65041 aaattcagtt gctcaatgac cggcatcacc agaccgaccg cggttaaaca cgccacggtc
    65101 gcggaaccct gaatgatgcg caccgccgcc gccagcacaa agcaggtaat ggcaatcggc
    65161 agtcccatac cggttaacgc ttcgcccagc gccgggccga cgccggagtc aaccagtacc
    65221 tgtttgaaca ccccgcctgc gccaatcacc agcagaataa tgcccgccgg ttgtagcgcg
    65281 tggccgcaga tttccatcac tttgtctttc ggcatcccct ggcgcatcgc caggccgtaa
    65341 atcgctacca gacaagcgac cagaatcgca gtgaaggggt ggccgataaa ctcaaaccat
    65401 tcataagcgg tggaaccttc cggcacaaag cgcgcggcga tcgttttcag tcctaccagc
    65461 accaacggca gcaggatcag cgacaggctg aagccgaaag aaggcatttt gccttcgccc
    65521 agatgcggct cggtaatgtc gtcaggaata cgcagctcaa cgtaacggct gataaaattc
    65581 ccccacagcg gcccggcgat aatcatgcca ggaatggcgg cgcacagccc aatcaggatc
    65641 atccagccga aatcagcatg catctgggaa gccagcagca tcggcgcagg cccaggcaac
    65701 aaaaacgccg cggctgccgc cacgcccgca aacagcggaa tgaccagctt caccaggttt
    65761 gtgccggtat gacgcgccat agagaacgcc acacttatca gcagcacaat cgccacttca
    65821 aagaatagcg ggagcgcgca aatcagcccg gcaaggccaa tcgcatagtg cgcgcggtta
    65881 tggccaaagg atttaagcat tttcacggct atctgatcga ccgcgccggt ttcatgcaga
    65941 attttaccga acatcgcccc cagcgcgacc acaatcgcca ggaagcccag cgtgccgccc
    66001 atcccttttt ccatggtcgc ggcgatttta tcaagcggca tccctgaaaa aagccccgcg
    66061 cccattgaga cgaccattaa cgcgacgaag gcgtgcatac gcgccttcat cacgagaaac
    66121 agcagcagta agacggaacc gacggcggtt aaaaccagtg ttaatgtact cacagcgtac
    66181 tgcctttatt gatgacctca atggtgctcg ccacaacgcc ttccagcggc tggtcgatat
    66241 ccaccaccag aacatcgcgt tcgtcggcac ccggctcttg cagcgtttca aactgcgtca
    66301 ccagcatctg ggttttgaag aaatgacctt tgcgcgcttt cagacggctt tcaatgacgt
    66361 cgaaatcacc tttcagatag ataaaggaga gattcgggtt tccctcgcgc agcaggtcgc
    66421 gatagtgttt tttcagtgcg gaacagacaa tcagcgagat tttattggta cgctgcatcg
    66481 cgaaagcggc gtcgttcagc gcctgcaacc acggtttgcg gtcatcatca ttcaacggct
    66541 cgccggaagc cattttttca atattgcagc gcggatgcag aaaatcgccg tccagaaacg
    66601 cggcatgaag ctgatgcgcc acggcgcttg cgacagcgga tttaccgctg cctgatacgc
    66661 ccatcagaac gtaaacgtgg tgatcatgat tagtcgtgct caaagcggga ccccactcta
    66721 caagttgcaa aatttgttac gggtaactgt tatcggtaac attgtccaac cgcaccattc
    66781 acgacgcaat gaccattcgt gccaaaagtg aataagtgtg agctacttca aagttgtcag
    66841 actaaataga tccgcccggt gacaaggtga aacctaaatc taacattttc ggcgtgaccg
    66901 tttcgccgcg aatgcgggcc aacagacgtt ccgcgccaat gctgcccatt cgctcgcgcg
    66961 gcgtcaggac gcttgccaga cgcggttcca tcacctggcc gatgtcatga ccgtggaacc
    67021 cggcgatcgc catgtcgtcc gggattttta gccccaggcg ctggcattcg aaggccgccc
    67081 ccaccgccag gtcatcgttg gtgcaaaaaa taccgtcaag ctgtgggtat tcgcgtcgcg
    67141 cctggcgcat gagttcgata ccggaagagt aggatgaaga ttgctccatc atcacactgt
    67201 aaggaaccag gccggcgtcc cgcatcgcct gttcatagcc cttctgcttg atgatagtac
    67261 gttcgtcgag gcgcgccccc agataggcga tatgacgatg accacgcgcg ataatcgcgg
    67321 cggtcatctg acgggcggcc tcgaagttgt caaaaccaac ggcaatatcg agacacggcg
    67381 actggctgtc catcagttcc accaccggaa tcccggcgac ttcgatcatt tttaaggtgc
    67441 gcggcgtatg ggtacgttct gtgaggataa gaccgtcgat attccaggag agcatcgatt
    67501 ccaggcgctc ctgctccatc tccggtttat agccgtagtg cgccagcatg gtctgatacc
    67561 cgtgggcatc ggtgacggcc tcaatgccgc gtaacacttc cgcaaagacc tggttggtga
    67621 gagacggtaa cagcacgccg atagcgcgac tggtggcgtt agaaaggata tcaggagcgc
    67681 gattgggaat ataacccagc tcatcaagtg cagcggcaat tttgccccgc agcgccacgg
    67741 agacctgctc cgggttacgc aaaaagcggc tgaccgtcat tttggtcacg cccacgcggt
    67801 cggctacatc ctgaagtacg ggtcttttct ttttcatcgt cctgaagcgt taaaaaggga
    67861 tagatttccc cagtttacca cggacgtgcg tgaaccttcg cagagaaaaa ggagttttta
    67921 ttatgagaaa tacacaaaat cattcgagtt gcatcaaggc ggcgacgcag tgacaaattc
    67981 gtcaggaacg aatttgaaca accgaaggtt gcctctggtg agggacaagg atgtccctca
    68041 gtaaatcccc gggagcgtac attaagtacg cgaccggggt gagcgacaaa tctgccggga
    68101 gcagatttga acgctgctcg cagcggcccc gaaggggcga ggcctatgga tgggccgagt
    68161 aataaagcca acacagatgc agcttgaagg atgacgtgta tttttagact ggcggcaggt
    68221 caaacagtaa cacttcactg tcgctgtcgg catgaatcga gattgcctgc tcatcccaaa
    68281 tcgccaggcc gtcgctggtc gtcgctttgg taccgttaat ggtcacgtta ccttttacca
    68341 cctgtatcca gacgcggcgc tcggcggcaa tctgatgcac cgattgctca tctttgagca
    68401 gcgcccagcg gtacagctcc atatcctggt ggaccttcag cgaaccatcg cgagcatctg
    68461 gcgaaagcac cagttgcttg ccctgcgcgg cgtcgaagcg gcgctgttcg tagcgcggcg
    68521 tgatgcctgt ttcttgcgga atgatccaga tctggtacag ccgcagacga tccgttttgc
    68581 tcgggttgta ctcggagtgg cgaacgccgg tcccggcgct cataatctgg aattcacctg
    68641 ccggaacctg ttctttattg cccatactgt cctggtgttc tacagcacct tccagcacat
    68701 aggtcaaaat ttccatgtct ttatgcggat gcgtgccgaa accctggcct gcgtcgatca
    68761 catcgtcgtt aatcacacgt agcgccgaga accccataaa gttcggatcg taataatcgg
    68821 caaaagaaaa ggtatgccag gagtcaagcc agccatgatt cgcatgaccg cggtcgtttg
    68881 ctttgcgtaa gtagatcatt gtgttcaccc ccagatgttt tcgatggaat aagtgtggac
    68941 tcattccgtc cgggatcata gagggtgaaa attgactcct ctgttcaaaa aatatgaata
    69001 agcgcagagg agtctgtaag ggctatttag cgagggttat cgtcgcaggc gttgcctgtt
    69061 cgaaggcacg ttcgaggatt tccagattgg taagaacttc agattccttg acataattag
    69121 gcgtaccgat ggtcaacgtc tggtacagcg catcatagac gcgaccatag tcacccgttt
    69181 ccggtttcac ctcttctttc accgtaacgc cttcatcgtt aacatattcc agcacaccga
    69241 cggattcgtc agcggcaaaa cccggctcgc caggcataat gttcgctttc aggctggttt
    69301 cttgttgatc gataccgtat ttcacaaacg aacctttggt gccgtgaaca ataaacttcg
    69361 gatagtcgat tttcaccaga tggctggttt tcacaatggc tttcagggca ccgtagaaca
    69421 attgcgcttc aaaggtgtca tccggattcg ctttattacg caggctacga atgtcatacg
    69481 cgacatgatc cgggcggcca aatagcgaaa taatttgatc catagtgtgg acgccaagtc
    69541 catagaatgc gccatcctgc ggcaggcccg gtttggtttc tgctaccggg cggtaataat
    69601 cgaaatggct ttcaatttcg acaatcttgc ccagtttccc gctctcaatc gcttttttag
    69661 cagtgagaaa acaggaatca aaacgccgat tctgatatgg cgtgacggtc agtcctttgc
    69721 ttcgcgccag ttcgaacaac acttttgcct ccgccagcgt cggcgtgaaa ggtttctcaa
    69781 ccagcacatt tttacccgct tccagcgcgc gtttggcgta ttcgaaatgg ctgtcagcat
    69841 gcgtacagac gatcaccagt tttacctgcg gatcgcccaa cacctcatcc agatcgctgg
    69901 tgaagtgaat atgcgaatac tgcggcgcct gctcttccgg tttagcgtga cgacggaaaa
    69961 tatgcgcgac atgccaggta tctttacgat tcagaacgta ggggagatgg taacgggtgg
    70021 tacttttgcc gaatccaata aatgcgcagt gtaaggtcat gagacgatcc ttttgaagat
    70081 gattgtttac accatagcgc aaagcgtgag gagactgaat gttggattct ttgacggtgg
    70141 cggagaagcc ttttcgggcc tacaaaagca gatgcctcaa gatcggccgt cagcgtcgcg
    70201 gtcagtttgt tcacggcaag cgcgcagggc ccggagcgta ctaaatgtac gtgaggagca
    70261 cgagcacttc ccggggacaa aatgacaagt aagccaggct gaaacaaaac caaaaaaaaa
    70321 gccagcaaaa gctggccaaa ataaaactgg aagcaatgtg agcaatgtca tgctttcagg
    70381 ttatccgtag gggttcccct gaatgcaagg caataataat cattctcatt cgcacttgtc
    70441 tacttctttt tgcaaaaaaa tgcggttgac ggaattttct ttctcagcga gtgtaaatac
    70501 acaattaacc ctgcaggaga taaggaatga gtgaaatagt gatacgccac gctgaaccga
    70561 aagattacga cgccattcgt cagatccacg cccagccgga ggtgtaccac aacacgctac
    70621 aggttcctca tccttccctc gaaatgtggc aggcgcggct aaccgagcaa gccggggtta
    70681 aacaactggt tgcctgcatt gacgatattg tcgttggcca tctttctatt caggtcaccc
    70741 aacgtccccg tcgcagccac gtggccgatt ttggtatctg cgtggatgcc cggtggcaca
    70801 atcgcggcat tgccagcgcg ctgatccgca cgatgatcga catgtgtgac aactggctgc
    70861 gcgtcgagcg tattgagtta acggtgtttg ttgataacga gcccgcggtg gcggtgtata
    70921 agaagtacgg ctttgaaatc gaaggcaccg gtaagaaata cggcctgcgc aacggtgagt
    70981 acgttgatac gtactttatg gcgcgcgtga aatagcgctt ccccgcccca ccctgtgggg
    71041 cgaaacgtca caaaccttca caacattcca gttattgcag cctacttccc ctatatcaaa
    71101 acaataacca cttgaa
//
LOCUS       DAJVBX010000002        62883 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.002, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000002 DAJVBX010000000
VERSION     DAJVBX010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 62883)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62883)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62883
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.002"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            24..878
                     /locus_tag="OPV72_000055"
     CDS             24..878
                     /locus_tag="OPV72_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose bisphosphate family class II aldolase"
                     /protein_id="HCR9912479.1"
                     /translation="MFIISSKNMLQKAQHAGYAVPAFNIHNLETLQVVVETAAEMRSP
                     LIVAGTPGTFSYAGMGNIVAIAGDLAREYNLPLAIHLDHHESLADIESKVMAGIRSVM
                     IDGSHFPFEENVALVKSVVDFCHRYDTSVEAELGRLGGIEDDLVVDSKDALYTNPQQA
                     REFVARTGIDSLAVAIGTAHGMYAAEPKLDFERLAEIRALVDIPLVLHGASGLPESDI
                     RQAISLGVCKVNVATELKIAFSDALKEYFLQNPKANDPRHYMQPAKQAMKEVVRKVIH
                     VCGCEGQL"
     gene            889..1803
                     /gene="pfkB"
                     /locus_tag="OPV72_000056"
     CDS             889..1803
                     /gene="pfkB"
                     /locus_tag="OPV72_000056"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HCR9912480.1"
                     /translation="MIYTLTLNSAIDMNIFSDPLQPNIVNRTHHTEFCPNGKGVNVAL
                     VLDHFQIPAHILGIFGGFTGHYIVESLRTRKMPVTPAWVEEPTRINIFIHDGKQEYKL
                     VNPGSYIPDECKKQIITIISQLPDAEYLVISGSLPQGIESRFYAEIMHICQQKNIGVI
                     LDISHPSLRQLLEFKPLLIKPNDEEVKAIFGLTVSDDNDAKNTLTTLHALGAQNVLLT
                     LGAKGMYFSNGIDYWFCSAPTVDLVSSACAGDAALAAFLSQWLSTGEVEYALSLASAT
                     GADVASSAGLGQLAAIETLLSQIHVRKL"
     gene            1830..3257
                     /locus_tag="OPV72_000057"
     CDS             1830..3257
                     /locus_tag="OPV72_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCR9912481.1"
                     /translation="MKKIIAVTGCPTGIAHTFMAEEALKNAAKKLSVEIKVETNGASG
                     VENAIQPADLVDIAGVIIAADKDVLPDRFNGLPVIEVPVKEAIHHPAELINKVINGEA
                     PIRKGESTTSTEIIEKESLGRQIYKHLMSGVSNMLPFVVAGGILIAVSLLWGIYSADP
                     NSAEYNATAAMLMKIGQQAFSIMVPVFTAYIAFSISGRPGMVAGFVGGLLANTTGAGF
                     LGGIIAGFAAGYLMLWVKNRLEGLPRQYEGLKSIFIMPLIGVLVIGVLMSLLGQPVAA
                     INNSMMNWLASLQEANPILLGIVVGAMCSFDFGGPVNKAAYVTGTLLLGQGNFYFMAG
                     VSAACITPPLVIALATTFFPKGFSEEERAAGMVNYILGCTHITEGAIPFAAKDPLRVI
                     PMMMIASSISAVLSYSLRIQVPAPHGGFLILPLVSQPLAWVLCILAGSACGAMMLGLW
                     RLWAVRKNSVNTTPVAKAGGQNAAL"
     gene            3244..4050
                     /locus_tag="OPV72_000058"
     CDS             3244..4050
                     /locus_tag="OPV72_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HCR9912482.1"
                     /translation="MQLCEHDIFISDERLDKVTALHRVVEKLSAAGNTTPDYLRGMLD
                     REAQISTYLGNGIAIPHGTPESRDAVLQTGVKVIVFRHGVDWGDGNTAYLVTGIAARS
                     NEHLEILRQLTRVLSDDAILQALAKAESPSQVLALLTGSTTNTPAAMELHEGEQATFV
                     IHNPHGLHARPSAVLVKFIKQFQSHITVENLDNASGPVDGKNLMRVVSLGAKKGHRLL
                     FRAQGEDAQQALREIGELIASGAGEMITVPVTPPPEVMQPKRSWLSRLFN"
     gene            4248..5519
                     /gene="gatZ"
                     /locus_tag="OPV72_000059"
                     /pseudo
     CDS             4248..5519
                     /gene="gatZ"
                     /locus_tag="OPV72_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462170.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatZ"
     gene            5534..5998
                     /gene="gatA"
                     /locus_tag="OPV72_000060"
     CDS             5534..5998
                     /gene="gatA"
                     /locus_tag="OPV72_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIA"
                     /protein_id="HCR9912483.1"
                     /translation="MSQLFVRTGITFDSSQQALAHIGKEMLAKGVVHDSYPQALVERE
                     ASFPTGIALERHAVAIPHCEAVHAKSPAIYLIRPDKPVMFQQADDDEEIAVSLIIALI
                     VENPAAQLKLLRRLFGALQIPDTIEALLSAPDAELASCFEHKVLTAEQCVQV"
     gene            6029..6313
                     /gene="gatB"
                     /locus_tag="OPV72_000061"
     CDS             6029..6313
                     /gene="gatB"
                     /locus_tag="OPV72_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIB"
                     /protein_id="HCR9912484.1"
                     /translation="MKRKVIVACGGAVATSTMAAEEIKELCDANHIELDLVQCRVTEI
                     ETYMDGADLICTTARVDRAFGDIPVVHGMPFVSGVGIEALQQKILSILMG"
     gene            6317..7690
                     /locus_tag="OPV72_000062"
     CDS             6317..7690
                     /locus_tag="OPV72_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HCR9912485.1"
                     /translation="MFSEIMRYILDLGPTVMLPLVIIVFSKLLGMKLGDCFKSGLHIG
                     IGFVGIGLVIGLMLDSIGPAAKAMAEHFQINLHVIDVGWPGSSPMTWASQIALVAIPV
                     AIGVNVLMLVTRMTRVVNVDIWNIWHMTFTGAMLHLATGSYWLGILGVVVHAAFVYKL
                     GDWFAKDTRDYFGLEGIAIPHGSSAYLSPVAVLVDTIIEKIPGLNRIHFSADDVQKRF
                     GPFGEPVTVGFVMGLVIGVLAGYDTKAVLQLAVKTAAVMLLMPRVIKPIMDGLTPIAK
                     HARKRLQAKFGGQEFLIGLDPALLLGHTSVVSASLIFIPLTILIAVLVPGNQVLPFGD
                     LATIGFFIAMAVAVHQGNLFRTLISGVIIMGITLWIATQTIGLHTQLAANAGALKAGA
                     QVASLDQGGSPITWLLIQLFTWQNIVGFAVIAIIYLAGVLLTWRRARQFVAAEKATAL
                     QQSQIAS"
     gene            7734..8777
                     /gene="gatD"
                     /locus_tag="OPV72_000063"
     CDS             7734..8777
                     /gene="gatD"
                     /locus_tag="OPV72_000063"
                     /EC_number="1.1.1.251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HCR9912486.1"
                     /translation="MKSVVIHAEGDVRVEERPLPQLQAEDDVLVKVVSSGLCGSDIPR
                     IFAQGAHYYPITLGHEFSGYVESYGTGVTDMQPGDAVACVPLLPCFHCPQCERGYFSL
                     CKQYQFVGSRSEGGNAEYVVVKRANLFRLPSDMPIEDGAFIEPITVGLHAFHLAQGCE
                     GKNVIIVGAGTIGLLALQCARELGARSVTAIDINPQKLELAKALGATHTCNSREMTAD
                     DIQTALSDIQFDQLVLETAGTPQTVSLAIDITGPRAQLALVGTLHHDLTLTTRTFGLI
                     LRKELTLLGSWMNYSAPWPGEEWETAARLLAEKRLQLTPLIAHRGDAESFAEAVKALN
                     GAPMQGKILLQLS"
     gene            8888..9661
                     /locus_tag="OPV72_000064"
     CDS             8888..9661
                     /locus_tag="OPV72_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCR9912487.1"
                     /translation="MNSFERRNKIVDLINTQGSVLVMDLSNTFGISEVTIRADLRLLE
                     EKGLVTRFHGGAAKPGSHLAEGDNQEVILEDRYQLASDPKKRIAQAAAAMVEEGMTII
                     LDSGSTTLLIAEALARKSNITVITNSLPAAFTLSENKDLTLVVCGGTVRHKTHSMHGT
                     IAERSLHGISADVMFVGADGIDATNGITTFNEGYSISGVMAAAAHKVIAVLDATKFNR
                     RGFNQVLPMDKIDCVITDDTISKQDKAALAKTGVELMIV"
     gene            complement(9819..10682)
                     /gene="rsmI"
                     /locus_tag="OPV72_000065"
     CDS             complement(9819..10682)
                     /gene="rsmI"
                     /locus_tag="OPV72_000065"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HCR9912488.1"
                     /translation="MKQNESADNSQGQLFIVPTPIGNLADITQRALEVLQAVDLIAAE
                     DTRHTGLLLQHFGINARLFALHDHNEQQKAETLVAKLKEGQNIALVSDAGTPLINDPG
                     YHLVRTCREAGIRVVPLPGPCAAITALSAAGLPSDRFCYEGFLPAKSKGRRDALKAIE
                     AEPRTLIFYESTHRLLDSLEDMVAVWGESRYVVLARELTKTWETIHGAPVGELLAWVK
                     EDENRRKGEMVLIVEGHKAQEDDLPADALRTLALLQAELPLKKAAALAAEIHGVKKNA
                     LYKYALAQQEE"
     gene            10746..12797
                     /locus_tag="OPV72_000066"
     CDS             10746..12797
                     /locus_tag="OPV72_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein activator"
                     /protein_id="HCR9912489.1"
                     /translation="MVPSTFSRLNAARALPVVLAALLFAGCGTQAPDQSAAYMQGSAQ
                     ADSAFYLHQMQQSADDSKTNWQLLAIHALLKEGKSQQAVELFNQPPQNLNDTQRREQS
                     LLAVEIKLAQKDVAGAQALLDKLKPADFAPHQQARYWQAQIVASQGRPSLTLLRALIA
                     QEPLLAAKEKQKNIDATWQALSAMTPDQARTLVINADENVLQGWLDLQRVWFDNRNDP
                     DMLKAGIADWQKRYPQNPGAKMLPTQLVNVQRFKPASTSKIALLLPLNGQAAVFGRTI
                     QQGFEAAKNLGTQAVEMQPVAAPDAPVEPSVEETQPQMTNGVASPSQASVRDLTDDAP
                     SQSATPVSAPQTPPAQPATASAPADPSAELKIYDTSSQPLDQVLAQVQQDGASIVVGP
                     LLKNNVEALMKSNTPLNVLALNQPETVRSFPNICYFALSPEDEARDAAHHIYEQGKQS
                     PLLLIPRSALGDRVANAFTQEWQKLGGGIVLQQKFGSVAELKMGVNGGAGIALTGSPV
                     AASVPAQPGVTIGGLTIPAPPTDAQITGGGRVDAVYILATPEEIGFIKPMIAMRNGTQ
                     SGATLYASSRSAQGTSGPDFRLEMEGLQYSEIPMLAGGNTPLMQQALSAVHNDYSLAR
                     MYAMGVDAWTLANHFSQMRQVQGFEINGNTGALTASPDCVINRKLSWLKYQQGEIVPA
                     S"
     gene            12755..13150
                     /locus_tag="OPV72_000067"
     CDS             12755..13150
                     /locus_tag="OPV72_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HCR9912490.1"
                     /translation="MAQIPARGDCSRQLTRKQAGDAWEAAARLWLESKGLRFIAANVR
                     ERGGEIDLIMRDGKTTVFVEVRYRRSGLYGGAAASVTRSKQHKLLHTARLWLARQNGS
                     FDTVDCRFDVLAFTGNEIEWFRDAFNDHS"
     gene            13172..13762
                     /gene="diaA"
                     /locus_tag="OPV72_000068"
     CDS             13172..13762
                     /gene="diaA"
                     /locus_tag="OPV72_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaA initiator-associating protein DiaA"
                     /protein_id="HCR9912491.1"
                     /translation="MLERIKVCFTESIQTQIAAAEALPDAISRAAMTLVHSLLNGNKI
                     LCCGNGTSAANAQHFAASMINRFETERPSLPAIALNTDNVVLTAIANDRLHDEVYAKQ
                     VRALGHAGDVLLAISTRGNSRDIVKAVEAAVTRDMTIVALTGYDGGELAGLLGPQDVE
                     IRIPSHHSARIQEMHMLTVNCLCGLIDNTLFPHQDD"
     gene            13772..14347
                     /gene="yraP"
                     /locus_tag="OPV72_000069"
     CDS             13772..14347
                     /gene="yraP"
                     /locus_tag="OPV72_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divisome-associated lipoprotein YraP"
                     /protein_id="HCR9912492.1"
                     /translation="MKAFSPLAVLISALLLQGCVAAAVVGTAAVGTKAATDPRSVGTQ
                     VDDGTLELRVSSALSKDEQIKKETRINVTAYQGKVLLVGQSPNSELSARAKQIAMGVE
                     GTTEVYNEIRQGQPIGLGTASNDTWITTKVRSQLLTSDQVKSSNVKVTTENGEVFLLG
                     LVTEREGKAAADIASRVSGVKRVTTAFTYIK"
     gene            complement(14414..15049)
                     /locus_tag="OPV72_000070"
     CDS             complement(14414..15049)
                     /locus_tag="OPV72_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HCR9912493.1"
                     /translation="MSQVLITGATGLVGGHLLRMLINTPQVSAIAAPTRRPLTDIVGV
                     YNPHDPQLTDALAQVTDPVDIVFCCLGTTRREAGSKAAFIHADYTLVVDTALTGRRLG
                     AQHMLVVSAMGANAHSPFFYNRVKGEMEEALIAQNWPRLTIARPSMLLGDRTTRRVNE
                     TLFAPLFRLLPGNWKSIDARDVARAMLAEALEPAQEGVTILTSSQLREKAG"
     gene            15180..15698
                     /gene="yhbO"
                     /locus_tag="OPV72_000071"
     CDS             15180..15698
                     /gene="yhbO"
                     /locus_tag="OPV72_000071"
                     /EC_number="3.5.1.124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein/nucleic acid deglycase"
                     /protein_id="HCR9912494.1"
                     /translation="MSKKIAVLITDEFEDSEFTSPAAEFRQAGHEVITIEKEAGKTVK
                     GKKGEASVTIDKAIDDVRPDEFDALLLPGGHSPDYLRGDSRFVDFTRDFVNSGKPVFA
                     ICHGPQLLISADVIRGRKLTAVKPIIIDVKNAGAEFYDQEVVVDKDQLVTSRTPDDLP
                     AFNREALRLLGA"
     gene            complement(15678..16121)
                     /locus_tag="OPV72_000072"
     CDS             complement(15678..16121)
                     /locus_tag="OPV72_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbP family protein"
                     /protein_id="HCR9912495.1"
                     /translation="MDTLTAIGRWLAKQHVVTWCVHHEGELWCANAFYLFDAQNVALY
                     LLTDDKTRHAQMSGACAPVAGTVNGQPKTVARIRGVQFKGEIRRLEGQESDAARKAYL
                     RRFPVARVLPAPVWEIRLDEIKFTDNTLGFGKKLHWLRDSRAQQA"
     gene            16159..16476
                     /locus_tag="OPV72_000073"
     CDS             16159..16476
                     /locus_tag="OPV72_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462184.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HCR9912496.1"
                     /translation="MLMATMTPWYLYLIRTADNALYTGITTDVARRYRQHQTGKGAKA
                     LRGKGELTLAFAAQVGDRSLALRIEYRIKQLTKRQKERLVTEREAFEALLSSLQTPVL
                     KND"
     gene            complement(16463..16966)
                     /locus_tag="OPV72_000074"
     CDS             complement(16463..16966)
                     /locus_tag="OPV72_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HCR9912497.1"
                     /translation="MLIRVEIPIDAPGIDALLRRSFESDAEAKLVHDLREDGFLTLGL
                     VATDDEGQVVGYVAFSPVDVQGEDLQWVGMAPLAVDEKYRGQGLARQLVYEGLDSLNE
                     FGYAAVVTLGDPALYSRFGFELAAHYDLHCRWPGTESAFQVHRLAEDALEGVTGLVEY
                     HDHFNRF"
     gene            complement(16960..17484)
                     /locus_tag="OPV72_000075"
     CDS             complement(16960..17484)
                     /locus_tag="OPV72_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SCP2 domain-containing protein"
                     /protein_id="HCR9912498.1"
                     /translation="MLDKLRSRLVHAGPSLMSVPVKLTPFALKRQVLEQVLSWQFRQA
                     LADGELEFLEGRWLSIHVRDIDLKWYTTVENEKLIVSQQADADVSFSADASDLLMIAA
                     RKQDPDTLFFQRRLVIEGDTELGLYVKNLMDAIELEQMPKALRIMLLQLADFVEAGMK
                     NSPETKQTSVGEPC"
     gene            17701..18696
                     /locus_tag="OPV72_000076"
     CDS             17701..18696
                     /locus_tag="OPV72_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017457364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HCR9912499.1"
                     /translation="MELLCPAGNLPALKAAIENGADAVYIGLKDDTNARHFAGLNFTE
                     KKLQEAVSFVHQHRRKLHIAINTFAHPDGYARWQRAVDMAAQLGADALILADLAMLEY
                     AAERYPHIERHVSVQASATNEEAIRFYHRNFDVHRVVLPRVLSIHQVKQLARVTPVPL
                     EVFAFGSLCIMAEGRCYLSSYLTGESPNTVGACSPARFVRWQQTPQGLESRLNDVLID
                     RYQDGENAGYPTLCKGRYLVDGERYHALEEPTSLNTLELLPELMAANIASVKIEGRQR
                     SPAYVSQVAKVWRQAIDRCKAAPQNFVPQRDWMETLGAMSEGTQTTLGAYHRKWQ"
     gene            18687..19583
                     /locus_tag="OPV72_000077"
     CDS             18687..19583
                     /locus_tag="OPV72_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462188.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HCR9912500.1"
                     /translation="MAVRGAMKYSLGPVLYYWPKETLEDFYQQAAKSSADIIYLGEAV
                     CSKRRATKVGDWLEMAKSLAASGKQVALSTLALVQASSELSELKRYVDNGDFLLEASD
                     LGVVNLCAERKLPFVAGHALNCYNAVTLRRLLKEGMVRWCMPVELSRDWLVNLLNQCD
                     ELGIRNQFEVEVLSYGHLPLAYSARCFTARSEDRPKDECETCCIKYPNGRDVLSQENQ
                     QVFVLNGIQTMSGYVYNLGNELTSMQGLVDIVRLSPLGTETFAMLDAFRANENGGAPL
                     PLAAHSDCNGYWKRLAGLELQA"
     gene            19761..20768
                     /locus_tag="OPV72_000078"
     CDS             19761..20768
                     /locus_tag="OPV72_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HCR9912501.1"
                     /translation="MTDKTIPFSVLDLAPIPEGSSAKEAFTHSLDLARLAEKRGYHRY
                     WLAEHHNMTGIASAATSVLIGYLAANTTTLHLGSGGVMLPNHSPLVIAEQFGTLNTLY
                     PGRIDLGLGRAPGSDQPTMRALRRHMSGDIDNFPRDVAELVDWFDARDPNPHVRPVPG
                     YGEKIPIWLLGSSLYSAQLAAQLGLPFAFASHFTPDMLFQALHLYRTQFKPSARLEKP
                     YAMVCINIIAADSNRDAEFLFTSMQQAFVKLRRGETGQLPPPIENMETFWSPSEQYGV
                     QQALSMSLVGDKAKVRHGLVSILRETQADEIMVNGQIFDHQARLHSFDLAMDVKQELL
                     G"
     gene            complement(20859..22103)
                     /gene="mtr"
                     /locus_tag="OPV72_000079"
     CDS             complement(20859..22103)
                     /gene="mtr"
                     /locus_tag="OPV72_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan permease"
                     /protein_id="HCR9912502.1"
                     /translation="MATLTTTQTSPSLLGGVVIIGGTIIGAGMFSLPVVMSGAWFFWS
                     MAALVFTWFCMLHSGLMILEANLNYRIGSSFDTITKDLLGKGWNVVNGISIAFVLYIL
                     TYAYISASGSILHHTFAEMSLNVPARAAGFAFALLVAFVVWLSTKAVSRMTAIVLGAK
                     VITFFLTFGSLLGHVQPTTLFNVAESHASYTPYLLMTLPFCLASFGYHGNVPSLMKYY
                     GKDPRTIVKCLIYGTLLALALYSVWLLGTMGNIPRPEFIGIAQKGGNIDVLVQALSGV
                     LNSRSLDLLLVVFSNFAVASSFLGVTLGLFDYLADLFGFDDSAMGRFKTALLTFLPPM
                     IGGLLYPNGFLYAIGYAGLAATIWAAIVPALLARKSRERFGSPKFRVWGGKPMIALIL
                     VFGVGNAVIHILSSFNLLPVYQ"
     gene            complement(22257..24146)
                     /gene="deaD"
                     /locus_tag="OPV72_000080"
     CDS             complement(22257..24146)
                     /gene="deaD"
                     /locus_tag="OPV72_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312070.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase DeaD"
                     /protein_id="HCR9912503.1"
                     /translation="MAEFETTFADLGLKAPILEALTDLGYEKPSPIQAECIPHLLGGR
                     DVLGMAQTGSGKTAAFSLPLLNNLDPELKAPQILVLAPTRELAVQVAEAMTDFSKHMR
                     GVNVVALYGGQRYDVQLRALRQGPQIVVGTPGRLLDHLKRGTLDLSKLSGLVLDEADE
                     MLRMGFIEDVETIMAQIPEGHQTALFSATMPEAIRRITRRFMKEPQEVRIQSSVTTRP
                     DISQSYWTVWGMRKNEALVRFLEAEDFDAAIIFVRTKNATLEVAEALERNGYNSAALN
                     GDMNQALREQTLERLKDGRLDILIATDVAARGLDVERISLVVNYDIPMDSESYVHRIG
                     RTGRAGRAGRALLFVENRERRLLRNIERTMKLTIPEVELPNAELLGKRRLEKFAAKVQ
                     QQLESSDLDQYRALLAKIQPSAEGEELDLETLAAALLKMAQGERPLILPPDAPMRPKR
                     EFRDRDDRGPRDRNDRGPRGDREERPRRERRDVGDMQLYRIEVGRDDGVEVRHIVGAI
                     ANEGDISSRYIGNIKLFASHSTIELPKGMPGEVLQHFTRTRILNKPMNMQLLGDAVPH
                     AGGERRGGGRSFSGERREGGRNFSGERREGGRGDGRRFSGERRESRGPRRDDSTGRRR
                     FGGDA"
     gene            complement(24139..24219)
                     /gene="yrbN"
                     /locus_tag="OPV72_000081"
     CDS             complement(24139..24219)
                     /gene="yrbN"
                     /locus_tag="OPV72_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YrbN"
                     /protein_id="HCR9912504.1"
                     /translation="MKIADQFHDELCRLAAINFEAHVLHG"
     gene            complement(24325..25209)
                     /gene="nlpI"
                     /locus_tag="OPV72_000082"
     CDS             complement(24325..25209)
                     /gene="nlpI"
                     /locus_tag="OPV72_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020802045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein NlpI"
                     /protein_id="HCR9912505.1"
                     /translation="MKPFLRWCFVATALTLAGCSNSAWRKSEVLAVPLQPTLQQEVIL
                     ARMEQILASRALTDDERAQLLYERGVLYDSLGLRALARNDFSQALAIRPDMPEVFNYL
                     GIYLTQAGNFDAAYEAFDSVLELDPTYNYAHLNRGIALYYGGRDKLAQDDLLAFYQDD
                     PNDPYRSLWLYLVEQKLNEKQAKEALKARFEKSDKEQWGWNIVEFYLGDISEATLMER
                     LKADATDNTSLAEHLSETNFYLGKYYLSLGDLDSATALFKLAVANNVHNFVEHRYALL
                     ELSLLGQDQDDLAESDQQ"
     gene            complement(25319..27454)
                     /gene="pnp"
                     /locus_tag="OPV72_000083"
     CDS             complement(25319..27454)
                     /gene="pnp"
                     /locus_tag="OPV72_000083"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HCR9912506.1"
                     /translation="MLNPIVREFQYGQHTVTLETGMMARQATAAVMVSMDDTAVFVTV
                     VGQKKAKPGQDFFPLTVNYQERTYAAGRIPGSFFRREGRPSEGETLIARLIDRPVRPL
                     FPEGFVNEVQVIATVVSVNPQVNPDIVAMIGASAALSLSGIPFNGPIGAARVGYINDQ
                     YVLNPTQDELKESKLDLVVAGTEAAVLMVESEAELLSEDTMLGAVVFGHEQQQVVIQA
                     INDLVKEAGKPRWDWQPEAVNDALNARVAALAESRLSDAYRITDKQERYAQVDVIKSE
                     TIEQLIAEDETLDANELGEILHAIEKNVVRSRVLAGEPRIDGREKDMIRGLDVRTGVL
                     PRTHGSALFTRGETQALVTATLGTARDAQVLDELMGERTDSFLFHYNFPPYSVGETGM
                     VGSPKRREIGHGRLAKRGVLAVMPDMDKFPYTVRVVSEITESNGSSSMASVCGASLAL
                     MDAGVPIKAAVAGIAMGLVKEGDNYVVLSDILGDEDHLGDMDFKVAGSRDGISALQMD
                     IKIEGITKEIMQVALNQAKGARLHILGVMEQAINAPRGDISEFAPRIHTIKISTDKIK
                     DVIGKGGSVIRALTEETGTTIEIEDDGTVKIAATDGEKAKYAIRRIEEITAEIEVGRI
                     YNSKVTRIVDFGAFVAIGGGKEGLVHISQIADKRVEKVTDYLQMGQEVPVKVLEVDRQ
                     GRVRLSIKEATEQSQPAAAPEAPASEQAE"
     gene            complement(27696..27965)
                     /gene="rpsO"
                     /locus_tag="OPV72_000084"
     CDS             complement(27696..27965)
                     /gene="rpsO"
                     /locus_tag="OPV72_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004933502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HCR9912507.1"
                     /translation="MSLSTEATAKIVSEFGRDANDTGSTDVQVALLTAQINHLQGHFA
                     EHKKDHHSRRGLLRMVSQRRKLLDYLKRKDVARYTALIERLGLRR"
     gene            complement(28116..29060)
                     /gene="truB"
                     /locus_tag="OPV72_000085"
     CDS             complement(28116..29060)
                     /gene="truB"
                     /locus_tag="OPV72_000085"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HCR9912508.1"
                     /translation="MSRPRRRGRDIHGVLLLDKPQGMSSNDVLQKVKRIYNANRAGHT
                     GALDPLATGMLPICLGEATKFSQYLLDSDKRYRVIARLGQRTDTSDADGQIVQERPVT
                     FSAEQLASALETFRGDIEQIPSMYSALKYQGRKLYEYARQGIEVPREARPITVYELLF
                     IRHEGNELELEVHCSKGTYIRTIIDDLGEKLGCGAHVTYLRRLTVSKYPVDRMVTLEH
                     LQTLVAQAEQQGVPAAQLLDPLLMPMDSPASDYPVVNLPLTSSVYFKNGNPVRTTGAP
                     LKGLVRVTEGEDDKFIGMGEIDDEGRVAPRRLVVEYPA"
     gene            complement(29060..29461)
                     /gene="rbfA"
                     /locus_tag="OPV72_000086"
     CDS             complement(29060..29461)
                     /gene="rbfA"
                     /locus_tag="OPV72_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001712908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HCR9912509.1"
                     /translation="MAKEFGRPQRVAQEMQKEIALILQREIKDPRVGMMTTVSGVEMS
                     RDLAYAKVFVTFLNDQDEAAVKNGIKALQEASGFIRSLLGKAMRLRIVPELTFFYDNS
                     LVEGMRMSNLVTNVVKHDEERRVNPDDSKED"
     gene            complement(29682..32360)
                     /gene="infB"
                     /locus_tag="OPV72_000087"
     CDS             complement(29682..32360)
                     /gene="infB"
                     /locus_tag="OPV72_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HCR9912510.1"
                     /translation="MTDLTLKALAAERQVSVDRLVQQFADAGIRKSADDSVSAQEKQT
                     LLAHLNREAVSGPDKLTLQRKTRSTLNIPGTGGKSKSVQIEVRKKRTFVKRDPQEAER
                     LAAEEQAQREAEEQARREAEEQAKREAQQKAEREAAEQAKREAAEKAKREAAEKDKVS
                     NQQTDDMTKTAQAEKARRENEAAELKRKAEEEARRKLEEEARRVAEEARRMAEENKWT
                     ATPEPVEDTSDYHVTTSQHARQAEDENDREVEGGRGRGRNAKAARPAKKGKHAESKAD
                     REEARAAVRGGKGGKRKGSSLQQGFQKPAQAVNRDVVIGETITVGELANKMAVKGSQV
                     IKAMMKLGAMATINQVIDQETAQLVAEEMGHKVILRRENELEEAVMSDRDTGAAAEPR
                     APVVTIMGHVDHGKTSLLDYIRSTKVASGEAGGITQHIGAYHVETDNGMITFLDTPGH
                     AAFTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAGVPVVVAVNKIDKPEAD
                     PDRVKNELSQYGILPEEWGGESQFVHVSAKAGTGIDELLDAILLQAEVLELKAVRKGM
                     ASGAVIESFLDKGRGPVATVLVREGTLHKGDIVLCGFEYGRVRAMRNELGQEVLEAGP
                     SIPVEILGLSGVPAAGDEVTVVRDEKKAREVALYRQGKFREVKLARQQKSKLENMFVN
                     MTEGEVHEVNIVLKADVQGSVEAISDSLLKLSTDEVKVKIIGSGVGGITETDATLAAA
                     SNAILVGFNVRADASARKVIESESLDLRYYSVIYNLIDEVKAAMSGMLSPELKQQIIG
                     LAEVRDVFKSPKFGAIAGCMVTEGTIKRHNPIRVLRDNVVIYEGELESLRRFKDDVNE
                     VRNGMECGIGVKNYNDVRVGDMIEVFEIIEIQRTIA"
     gene            complement(32385..33887)
                     /gene="nusA"
                     /locus_tag="OPV72_000088"
     CDS             complement(32385..33887)
                     /gene="nusA"
                     /locus_tag="OPV72_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005131833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HCR9912511.1"
                     /translation="MNKEILAVVEAVSNEKALPREKIFEALESALATATKKKYEQEID
                     VRVEIDRKSGDFDTFRRWLIVEEVTMPTKEITLEAARFEDESLNVGDYVEDQIESVTF
                     DRITTQTAKQVIVQKVREAERAMVVDQFRDQEGEIVTGVVKKVNRDNISLEIKSEGMA
                     GNAEAVILREDMLPRENFRPGDRIRGVLYAVRPEARGAQLFVTRSKPEMLIELFRIEV
                     PEIGEEVIEIKAAARDPGSRAKIAVKTNDKRIDPVGACVGMRGARVQAVSTELGGERI
                     DIVLWDDNPAQFVINAMAPADVASIVVDEDKHTMDIAVEAGNLAQAIGRNGQNVHLAS
                     QLSGWELNVMTVDDLQAKHQAEAHAAIEIFTKYLDIDEEFATVLVEEGFSTLEELAYV
                     PMKELLEIDGLDEPTVEALRERAKNALATLAQDQEASLGDNKPADDLLNLEGLDRDMA
                     FKLAARGVCTLEDLADQGIDDLADIEGLTDEKAGELIMAARNICWFGDEA"
     gene            complement(33915..34367)
                     /gene="rimP"
                     /locus_tag="OPV72_000089"
     CDS             complement(33915..34367)
                     /gene="rimP"
                     /locus_tag="OPV72_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004125659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HCR9912512.1"
                     /translation="MSTLEQKLTEMITAPVEALGYELVGIEFIRGRTSTLRIYIDSED
                     GINVDDCADVSHQVSAVLDVEDPISVAYNLEVSSPGLDRPMFTADHYARFQGEEVALV
                     LRMAVQNRRKWQGIIKAVDGEMITVTVEGKDEVFALSNIQKANLVPHF"
     gene            complement(34575..34651)
                     /locus_tag="OPV72_000090"
     tRNA            complement(34575..34651)
                     /locus_tag="OPV72_000090"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(34615..34617),aa:Met,seq:cat)
     gene            34995..36338
                     /gene="argG"
                     /locus_tag="OPV72_000091"
     CDS             34995..36338
                     /gene="argG"
                     /locus_tag="OPV72_000091"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HCR9912513.1"
                     /translation="MTTILKHLPAGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTAN
                     LGQPDEDDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNT
                     TPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDT
                     DFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEFLNSSVKIVN
                     PIMGVKFWDESVKIPAEEVTVRFEQGHPVALNGKTFSDDVEMMLEANRIGGRHGLGMS
                     DQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHSHGRQLGKLLYQG
                     RWFDSQALMLRDGLQRWVASQITGEVTLELRRGNDYSILNTVSDNLTYKAERLTMEKG
                     ESVFSPDDRIGQLTMRNLDITDTREKLFGYAKAGLLTASSATGLPQVENLENKAK"
     gene            complement(36536..36622)
                     /locus_tag="OPV72_000092"
     tRNA            complement(36536..36622)
                     /locus_tag="OPV72_000092"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(36586..36588),aa:Leu,seq:gag)
     gene            complement(36636..36968)
                     /gene="secG"
                     /locus_tag="OPV72_000093"
     CDS             complement(36636..36968)
                     /gene="secG"
                     /locus_tag="OPV72_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HCR9912514.1"
                     /translation="MYEALLVVFLIVAIGLVGLIMLQQGKGADMGASFGAGASATLFG
                     SSGSGNFMTRMTAVLATLFFIISLVLGNINSNKTNKGSEWENLSAPAKTEQTQPAAPA
                     QPTSDIPR"
     gene            complement(37191..38528)
                     /gene="glmM"
                     /locus_tag="OPV72_000094"
     CDS             complement(37191..38528)
                     /gene="glmM"
                     /locus_tag="OPV72_000094"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HCR9912515.1"
                     /translation="MSNRKYFGTDGIRGRVGNAPITPDFVLKLGWAAGKVLARHGSRK
                     IIIGKDTRISGYMLESALEAGLAAAGLSASFTGPMPTPAVAYLTRTFRAEAGIVISAS
                     HNPFYDNGIKFFSIDGTKLPDDVEEAIEAEMEKEITCVDSAELGKASRIVDAAGRYIE
                     FCKGTFPNELSLNGLKVVVDCANGATYHIAPNVLRELGATVIAIGCEPNGVNINEEVG
                     ATDVRALQARVLAEKADLGIALDGDGDRVIMVDHEGNKVDGDQIMYIIAREGLRQGQL
                     RGGAVGTLMSNMGLELALKQLGIPFARAKVGDRYVLEKLQEKGWRIGAENSGHVILLD
                     KTTTGDGIVAGLQVLAAMVRNHMSLHDLCSGMKMFPQILVNVRYTAGSGDPLENEAVK
                     AVTADVEATLGNRGRVLLRKSGTEPLIRVMVEGEDEAQVTAFAHRIADAVKAV"
     gene            complement(38521..39369)
                     /gene="folP"
                     /locus_tag="OPV72_000095"
     CDS             complement(38521..39369)
                     /gene="folP"
                     /locus_tag="OPV72_000095"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HCR9912516.1"
                     /translation="MKLFAQGATLDLTHPHVMGILNVTPDSFSDGGAHNTLIEAVKHA
                     NLMVNTGATIIDVGGESTRPGAAEVSVEEELDRVIPVLEAIAQRFEVWISVDTSKPEV
                     IREAARAGAHIINDVRSLSEPGALEAAAETGLPVSLMHMQGNPKTMQEAPKYDDVFAE
                     VNRYFIEQIARCEKAGIAKEKLLLDPGFGFGKNLSHNYTLLARLGEFHHFNLPLLVGM
                     SRKTMVGQLLNVGPSDRLNGSLACAVIAAMQGAQIIRVHDVKETVEAMRVVEATLSAK
                     GNKRYE"
     gene            complement(39474..41408)
                     /gene="ftsH"
                     /locus_tag="OPV72_000096"
     CDS             complement(39474..41408)
                     /gene="ftsH"
                     /locus_tag="OPV72_000096"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014833437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HCR9912517.1"
                     /translation="MAKNLILWLVIAVVLMSVFQSFGPSESNGRKVDYSTFLQEVNQD
                     QVREARINGREINVTKKDSNRYTTYIPINDPKLLDNLLTKNVKVVGEPPEEPSLLASI
                     FISWFPMLLLIGVWIFFMRQMQGGGGKGAMSFGKSKARMLTEDQIKTTFADVAGCDEA
                     KEEVAELVEYLREPSRFQKLGGKIPKGVLMVGPPGTGKTLLAKAIAGEAKVPFFTISG
                     SDFVEMFVGVGASRVRDMFEQAKKAAPCIIFIDEIDAVGRQRGAGLGGGHDEREQTLN
                     QMLVEMDGFEGNEGIIVIAATNRPDVLDPALLRPGRFDRQVVVGLPDVRGREQILKVH
                     MRRVPLATDIDAAIIARGTPGFSGADLANLVNEAALFAARGNKRVVSMVEFEKAKDKI
                     MMGAERRSMVMTEAQKESTAYHEAGHAIIGRLVPEHDPVHKVTIIPRGRALGVTFFLP
                     EGDAISASRQKLESQISTLYGGRLAEEIIYGVEHVSTGASNDIKVATNLARNMVTQWG
                     FSEKLGPLLYAEEEGEVFLGRSVAKAKHMSDETARIIDQEVKALIERNYNRARQILTD
                     NMDILHAMKDALMKYETIDAPQIDDLMARREVRPPAGWEDPNGTNNSDSNGTPQAPRP
                     VDEPRTPNPGNTMSEQLGDK"
     gene            complement(41512..42138)
                     /gene="rlmE"
                     /locus_tag="OPV72_000097"
     CDS             complement(41512..42138)
                     /gene="rlmE"
                     /locus_tag="OPV72_000097"
                     /EC_number="2.1.1.166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uridine(2552)-2'-O)-methyltransferase
                     RlmE"
                     /protein_id="HCR9912518.1"
                     /translation="MTGKKRSASSSRWLQEHFSDKYVQQAQKKGLRSRAWFKLDEIQQ
                     SDKLFKPGMTVVDLGAAPGGWSQYVVTQIGGKGRIIACDLLPMDPIVGVDFLQGDFRD
                     ELVMKALLERVGDSKVQVVMSDMAPNMSGTPAVDIPRAMYLVELALDMCRDVLAPGGS
                     FVVKVFQGEGFDEYLREIRSLFTKVKVRKPDSSRARSREVYIVATGRK"
     gene            42265..42558
                     /gene="yhbY"
                     /locus_tag="OPV72_000098"
     CDS             42265..42558
                     /gene="yhbY"
                     /locus_tag="OPV72_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014833438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HCR9912519.1"
                     /translation="MNLSTKQKQHLKGLAHPLKPVVMLGNNGLTEGVLAEIEQALEHH
                     ELIKVKIASEDRETKTLIVDAIVRETGACNVQVIGKTLVLYRPTKERKISLPR"
     gene            complement(42714..43190)
                     /gene="greA"
                     /locus_tag="OPV72_000099"
     CDS             complement(42714..43190)
                     /gene="greA"
                     /locus_tag="OPV72_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006178768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HCR9912520.1"
                     /translation="MQAIPMTLRGAEKLREELDFLKSVRRPEIIAAIAEAREHGDLKE
                     NAEYHAAREQQGFCEGRIKDIEAKLSNAQVIDVTKMPNNGRVIFGATVTVLNLDTDEE
                     QTYRIVGDDEADFKQNLISVNSPIARGLIGKEQDDVVVIKTPGGDVEYEVLKVEYL"
     gene            43438..44871
                     /gene="dacB"
                     /locus_tag="OPV72_000100"
     CDS             43438..44871
                     /gene="dacB"
                     /locus_tag="OPV72_000100"
                     /EC_number="3.4.16.4"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine-type D-Ala-D-Ala carboxypeptidase"
                     /protein_id="HCR9912521.1"
                     /translation="MRFSRFIIGLTTSIAFSVQAANIDEYIKQLPAGANLALMVQKIG
                     APAPAIDYHSQQMALPASTQKVITALAALIQLGPDFRFTTTLETKGNVDNGILKGDLI
                     ARFGGDPTLRRQDIRNMVATLKKSGVTQIDGNVLIDTSIFASHDKAPGWPWNDLTQCF
                     SAPPAAAIVDRNCFSVSLYSAQKPNDLAFIRVASYYPVTMFSQVRTLPRGSADAQYCE
                     LDVVPGDLNRYTLTGCLPQRADPLPLAFAIQDGASYAGAILKQELKEAGITYRGTLLR
                     QTQVNEPGTIVASKQSAPLHDLLKIMLKKSDNMIADTVFRMIGHVRFNVPGTWRAGSD
                     AVRQILRQQAGIDIGNTIIADGSGLSRHNLIAPATMMQVLQYIAQHDNELNFISMLPL
                     AGYDGSLQYRAGLHQAGVDGKVSAKTGSLQGVYNLAGFITTASGQRMAFVQYLSGYAV
                     PPADQRNRRIPLVRFESRLYKDIYQNN"
     gene            complement(45002..46174)
                     /gene="cgtA"
                     /locus_tag="OPV72_000101"
     CDS             complement(45002..46174)
                     /gene="cgtA"
                     /locus_tag="OPV72_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Obg family GTPase CgtA"
                     /protein_id="HCR9912522.1"
                     /translation="MKFVDEASILVVAGDGGNGCVSFRREKYIPKGGPDGGDGGDGGD
                     VWMEADENLNTLIDYRFEKSFRAERGQNGASRDCTGKRGKDVTIKVPVGTRVIDQGTG
                     ETMGDMTKHGQRLLVAKGGWHGLGNTRFKSSVNRTPRQKTNGTPGDKRDLLLELMLLA
                     DVGMLGMPNAGKSTFIRAVSAAKPKVADYPFTTLVPSLGVVRMDSEKSFVVADIPGLI
                     EGAAEGAGLGIRFLKHLERCRVLLHLIDIDPIDGSDPVENARIIIGELEKYSQDLAAK
                     PRWLVFNKIDLMDKSEAEEKAKAIAEALGWEGKYYLISAASQLGVKDLCWDVMTFIIE
                     NPIAQAEEAKQPEKVEFMWDDYHRQQLAEVEEDADDDWDDDWDEDDEEGVEFIYKR"
     gene            complement(46190..47155)
                     /locus_tag="OPV72_000102"
     CDS             complement(46190..47155)
                     /locus_tag="OPV72_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012135318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HCR9912523.1"
                     /translation="MKQQAGIGILLALTTAMCWGALPIAMKQVLEVMEPSTIVFYRFL
                     MASIGLGAILAVKRKLPPLRIFRKPRWLVLLAIATCGLFGNFILFSSSLQYLSPTASQ
                     VIGQLSPVGMMVASVFILKEKMRGTQVIGALMLLSGLVMFFNTSLIEIFTRLTDYTWG
                     VIFGVGAAMVWVSYGVAQKVLLRRLASQQILFLLYTLCTIALLPLAKPMVIAQLSDWQ
                     LACLIFCGLNTLVGYGALAEAMARWQAAQVSAIITLTPLFTLLFSDLLSMAWPDFFAR
                     PMLNLLGYLGAFVVVAGAMYSAIGHRIWGGLRKHETVVSQPRSGE"
     gene            complement(47285..47542)
                     /gene="rpmA"
                     /locus_tag="OPV72_000103"
     CDS             complement(47285..47542)
                     /gene="rpmA"
                     /locus_tag="OPV72_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004933559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HCR9912524.1"
                     /translation="MAHKKAGGSTRNGRDSEAKRLGVKRFGGEAVLAGSIIVRQRGTK
                     FHAGTNVGCGRDHTLFAKADGKVKFEVKGPKNRKYISIVAE"
     gene            complement(47562..47873)
                     /gene="rplU"
                     /locus_tag="OPV72_000104"
     CDS             complement(47562..47873)
                     /gene="rplU"
                     /locus_tag="OPV72_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015960603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HCR9912525.1"
                     /translation="MYAVFQSGGKQHRVSEGQTVRLEKLDIATGETIEFAEVLMIANG
                     EEVKIGVPFVDGGVIKAEVVAHGRGEKVKIVKFRRRKHYRKQQGHRQWFTDVKITGIS
                     A"
     gene            48132..49103
                     /gene="ispB"
                     /locus_tag="OPV72_000105"
     CDS             48132..49103
                     /gene="ispB"
                     /locus_tag="OPV72_000105"
                     /EC_number="2.5.1.90"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="octaprenyl diphosphate synthase"
                     /protein_id="HCR9912526.1"
                     /translation="MNLEKINELTAQDMAGVNATILEQLNSDVQLINQLGYYIISGGG
                     KRIRPMIAVLAARAVGYQGNAHVTIAALIEFIHTATLLHDDVVDESDMRRGKATANAA
                     FGNAASVLVGDFIYTRAFQMMTSLGSLKVLEVMSEAVNVIAEGEVLQLMNVNDPDITE
                     ENYMRVIYSKTARLFEAAAQCSGILAGCTPEQEKGLQDYGRYLGTAFQLIDDLLDYSA
                     DGEHLGKNVGDDLNEGKPTLPLLHAMRHGTPEQSAMIRTAIEQGNGRHLLEPVLEAMT
                     TCGSLEWTRQRAEEEADKAISALQILPDTPWREALIGLAHIAVQRDR"
     gene            49336..49623
                     /gene="sfsB"
                     /locus_tag="OPV72_000106"
     CDS             49336..49623
                     /gene="sfsB"
                     /locus_tag="OPV72_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator SfsB"
                     /protein_id="HCR9912527.1"
                     /translation="MESKLIDWHPADIIAGLRKKGTSMAAESRRNGLSSSTLANALTR
                     PWPKGELIIAKALGTEPWVIWPSRYHDPRTHEFIDRTRLMRARNKDKQNVE"
     gene            complement(49682..50941)
                     /gene="murA"
                     /locus_tag="OPV72_000107"
     CDS             complement(49682..50941)
                     /gene="murA"
                     /locus_tag="OPV72_000107"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HCR9912528.1"
                     /translation="MDKFRVQGPTTLQGEVTISGAKNAALPILFAALLAEEPVEIQNV
                     PKLKDVDTSMKLLSQLGAKVERNGSVHIDASQVNVFCAPYDLVKTMRASIWALGPLVA
                     RFGQGQVSLPGGCTIGARPVDLHITGLEQLGATIKLEEGYVKASVEGRLKGAHIVMDK
                     VSVGATVTIMCAATLAEGTTIIENAAREPEIVDTANFLVTLGAKIAGQGTDRITIEGV
                     ERLGGGVYRVLPDRIETGTFLVAAAISRGKILCRNAQPDTLDAVLAKLRDAGADIEVG
                     EDWISLDMHGKRPKAVNVRTAPHPAFPTDMQAQFTLLNLVAEGTGFITETVFENRFMH
                     VPELSRMGARAEIESNTVICHGVETLSGAQVMATDLRASASLVLAGCIAEGTTIVDRI
                     YHIDRGYERIEDKLRALGANIERVKGE"
     gene            complement(50995..51249)
                     /gene="ibaG"
                     /locus_tag="OPV72_000108"
     CDS             complement(50995..51249)
                     /gene="ibaG"
                     /locus_tag="OPV72_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417657.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BolA family iron metabolism protein IbaG"
                     /protein_id="HCR9912529.1"
                     /translation="MENHEIQSVLMNALSLQEVHVSGDGSHFQVIAVGEMFDGMSRVK
                     KQQTVYGPLMEYIADNRIHAVSIKAYTPAEWARDRKLNGF"
     gene            complement(51437..51733)
                     /gene="mlaB"
                     /locus_tag="OPV72_000109"
     CDS             complement(51437..51733)
                     /gene="mlaB"
                     /locus_tag="OPV72_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid asymmetry maintenance protein MlaB"
                     /protein_id="HCR9912530.1"
                     /translation="MTPQLTWTREADTLVLAGELDQDVLAPLWDARVEAMNGVTRIDL
                     SQISRVDTGGLALLAHLVNQAKKQGNAVSLSGVNDKVYALAQLYNLPEDVLPRM"
     gene            complement(51733..52368)
                     /gene="mlaC"
                     /locus_tag="OPV72_000110"
     CDS             complement(51733..52368)
                     /gene="mlaC"
                     /locus_tag="OPV72_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipid-binding protein MlaC"
                     /protein_id="HCR9912531.1"
                     /translation="MFKRLMMVALLVIAPLSAATAADQSNPYKLMNEAAQKTFDRLKN
                     EQPKIRANPDYLRDVVDQELLPYVQVKYAGALVLGRYYKEATPAQREAYFAAFREYLK
                     QAYGQALAMYHGQTYQIAPEQPLGDATIVPIRVTIIDPNGRPPVRLDFQWRKNTQTGN
                     WQAYDMIAEGVSMITTKQNEWSDLLRTKGIDGLTAQLKSISQQKITLDEKQ"
     gene            complement(52387..52938)
                     /gene="mlaD"
                     /locus_tag="OPV72_000111"
     CDS             complement(52387..52938)
                     /gene="mlaD"
                     /locus_tag="OPV72_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipid asymmetry maintenance
                     protein MlaD"
                     /protein_id="HCR9912532.1"
                     /translation="MQTKKNEIWVGVFLLVALLAALFVCLKAANVTSMRTEPTYKVYA
                     TFDNIGGLKVRSPVRIGGVVVGRVEDISLDPKTYLPRVTLDIEERYNHIPDTSSLSIR
                     TSGLLGEQYLALNVGFEDPELGTSILKDGSTIQDTKSAMVLEDMIGQFLYNSKGDDNK
                     NSGDAPAATEGHTEATTPAGETK"
     gene            complement(52943..53725)
                     /gene="mlaE"
                     /locus_tag="OPV72_000112"
     CDS             complement(52943..53725)
                     /gene="mlaE"
                     /locus_tag="OPV72_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014071945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid asymmetry maintenance ABC transporter
                     permease subunit MlaE"
                     /protein_id="HCR9912533.1"
                     /translation="MLLNALAALGHSGIKTVRTFGRAGLMLFNAIIGKPEFRKHAPLL
                     VRQLYNVGVLSMLIIIVSGVFIGMVLGLQGYLVLTTYSAETSLGMLVALSLLRELGPV
                     VAALLFAGRAGSALTAEIGLMRATEQLSSMEMMAVDPLRRVISPRFWAGVISLPLLTI
                     IFVAVGIWGGSLVGVSWKGIDAGFFWSAMQNAVDWRMDLVNCLIKSVVFAITVTWIAL
                     FNGYDAIPTSAGISRATTRTVVHASLAVLGLDFVLTALMFGN"
     gene            complement(53733..54545)
                     /gene="mlaF"
                     /locus_tag="OPV72_000113"
     CDS             complement(53733..54545)
                     /gene="mlaF"
                     /locus_tag="OPV72_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipid ABC transporter ATP-binding protein
                     MlaF"
                     /protein_id="HCR9912534.1"
                     /translation="MGQSAANLVDMRDVSFCRGERCIFDNISLTVPRGKITAIMGPSG
                     IGKTTLLRLIGGQIPPDKGEILFDGENVPAMSRSRLYTVRKRMSMLFQSGALFTDMNV
                     FDNVAYPLREHTNLPAPLLKSVVMMKLEAVGLRGAAKLMPSELSGGMARRAALARAIA
                     LEPDLIMFDEPFVGQDPITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIADHAWIM
                     ADKKIVAHGSAQALQENTDPRVRQFLDGIADGPVPFRYPAGDYHLDLLETGS"
     gene            54758..55735
                     /locus_tag="OPV72_000114"
     CDS             54758..55735
                     /locus_tag="OPV72_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium/sodium antiporter"
                     /protein_id="HCR9912535.1"
                     /translation="MLLAMALLIIGLLLVAYGADRLVFAASILCRTFGIPPLIIGMTV
                     VSIGTSLPEIIVSVAASLHGQLDLAVGAALGSNITNILLILGLAALVRPFTVHSDVLR
                     RELPLMLFVSVVAGSVLHDGQLSRSDGIFLLLLAVLWLLFIVKIARLAERQGNDSLTR
                     EQLAELPREDGLPVAFLWLGIALVIMPMATRMVIDNATVLANYFAMSELTLGLTVIAV
                     GTSLPELATAIAGVRKGENDIAVGNLIGANIFNLAIVLGLPALIAPGEINPLAFGRDY
                     SVMLLVSVVFALLCWRHPRQIGRGAGILLTGGFIVWLAMLYWLSPLLVG"
     gene            55749..56735
                     /gene="kdsD"
                     /locus_tag="OPV72_000115"
     CDS             55749..56735
                     /gene="kdsD"
                     /locus_tag="OPV72_000115"
                     /EC_number="5.3.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose-5-phosphate isomerase KdsD"
                     /protein_id="HCR9912536.1"
                     /translation="MSHLALQPGFDFQQAGKEVLEIEREGLAELDQYINQHFTLACEK
                     MFNCTGKVVVMGMGKSGHIGRKMAATFASTGTSSFFVHPGEAAHGDLGMVTPQDVVIA
                     ISNSGESSEIAALIPVLKRLHVPLICITGRPESSMARAADVHLCVKVPKEACPLGLAP
                     TSSTTATLVMGDALAVALLKARGFTAEDFALSHPGGALGRKLLLRVSDIMHTGDEIPH
                     VNKHATLRDALLEITRKNLGMTVICDESMKIDGIFTDGDLRRMFDMGGDMRQLGIAEV
                     MTPGGIRVRPGILAVDALNLMQSRHITSVLVADGDQLLGVLHMHDLLRAGVV"
     gene            56756..57322
                     /gene="kdsC"
                     /locus_tag="OPV72_000116"
     CDS             56756..57322
                     /gene="kdsC"
                     /locus_tag="OPV72_000116"
                     /EC_number="3.1.3.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate-8-phosphatase KdsC"
                     /protein_id="HCR9912537.1"
                     /translation="MSKAGASLATCYGPVSTHVMTKAENIRLLILDVDGVLSDGLIYM
                     GNNGEELKAFNVRDGYGIRCALTSNIEVAIITGRKAKLVEDRCATLGIVHLYQGQSNK
                     LIAFSDLLEKLAIAPENVAYVGDDLIDWPVMEKVGLSVAVADAHPLLIPRADYVTHIA
                     GGRGAVREVCDLLLLAQGKLDEAKGQSI"
     gene            57319..57894
                     /gene="lptC"
                     /locus_tag="OPV72_000117"
     CDS             57319..57894
                     /gene="lptC"
                     /locus_tag="OPV72_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter periplasmic protein
                     LptC"
                     /protein_id="HCR9912538.1"
                     /translation="MSKTRRWVIILLSLAILVLIGINLADKDDPAAVMVNSNDPTYKS
                     EHTDTVVYSPEGALSYRLIAQHVEYFSDQAVSWFTQPVLTTFDKDKVPTWSIKADKAK
                     LTNDRMLYLYGHVEVNALVPDAQLRRITTDNAQINLVTQDVTSNDLVTLYGTTFNSSG
                     LKMRGNLRSKNAELIEKVRTSYEIQNKQTQP"
     gene            57863..58417
                     /gene="lptA"
                     /locus_tag="OPV72_000118"
     CDS             57863..58417
                     /gene="lptA"
                     /locus_tag="OPV72_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide ABC transporter
                     substrate-binding protein LptA"
                     /protein_id="HCR9912539.1"
                     /translation="MKFKTNKLSLNLMLAGSLLAASIPAFAVTGDTEQPIHIDSDQQS
                     LDMQGNVVTFTGNVVMTQGTIKINADKVVVTRPGGEQGKEVIDGYGNPATFYQMQDNG
                     KPVKGHASHMHYELAKDFVVLTGNAYLEQLDSNITGDKITYLVKEQKMQAFSEKGKRV
                     TTVLVPSQLQDKNKGQTPAQKKSN"
     gene            58424..59149
                     /gene="lptB"
                     /locus_tag="OPV72_000119"
     CDS             58424..59149
                     /gene="lptB"
                     /locus_tag="OPV72_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003861862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter ATP-binding protein"
                     /protein_id="HCR9912540.1"
                     /translation="MATLTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTT
                     TFYMVVGIVPRDAGNIIIDDEDISLLPLHARARRGIGYLPQEASIFRRLSVFDNLMAV
                     LQIRDDLTAEQREDRANELMEEFHIEHLRDSMGQALSGGERRRVEIARALAANPKFIL
                     LDEPFAGVDPISVIDIKRIIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAH
                     GTPTEILQDEHVKRVYLGEDFRL"
     gene            59197..60630
                     /gene="rpoN"
                     /locus_tag="OPV72_000120"
     CDS             59197..60630
                     /gene="rpoN"
                     /locus_tag="OPV72_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HCR9912541.1"
                     /translation="MKQGLQLRLSQQLAMTPQLQQAIRLLQLSTLELQQELQQALENN
                     PLLEQTDLHDEIDTQQPQDDDPLDTADALEQKEMPEELPLDASWDEIYTAGTPSGPSG
                     DYIDDELPVYQGETTQSLQDYLMWQVELTPFSDTDRAIATSIVDAVDDTGYLTVSLDE
                     IRESMGDVEVDLDEVEAVLKRIQRFDPVGVAAKDLRDCLLIQLSQFDKSTPWLEEARL
                     IICDHLDLLANHDFRTLMRVTRLKEEVLKEAVNLIQSLDPRPGQSIQTGEPEYVIPDV
                     LVRKHNGRWTVELNSDSIPRLQINQHYAAMCNSARNDADSQFIRSNLQDAKWLIKSLE
                     SRNDTLLRVSRCIVEQQQAFFEQGEEYMKPMVLADIAQAVEMHESTISRVTTQKYLHS
                     PRGIFELKYFFSSHVNTEGGGEASSTAIRALVKKLIAAENPAKPLSDSKLTSLLSEQG
                     IMVARRTVAKYRESLSIPPSNQRKQLV"
     gene            60653..60940
                     /gene="hpf"
                     /locus_tag="OPV72_000121"
     CDS             60653..60940
                     /gene="hpf"
                     /locus_tag="OPV72_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome hibernation promoting factor"
                     /protein_id="HCR9912542.1"
                     /translation="MQLNITGHNVEITEALREFVTTKFAKLEQYFERINQVYVVLKVE
                     KVTHISDATLHVNGGEIHASAEGQDMYAAIDGLIDKLARQLTKHKDKLKQY"
     gene            61058..61549
                     /gene="ptsN"
                     /locus_tag="OPV72_000122"
     CDS             61058..61549
                     /gene="ptsN"
                     /locus_tag="OPV72_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS IIA-like nitrogen regulatory protein PtsN"
                     /protein_id="HCR9912543.1"
                     /translation="MINNDTTLQLSSVLNQECTRSGVHCQSKKRALEIISELAAKQLS
                     LPPQVVFEAILTREKMGSTGIGNGIAIPHGKLEEDTLRAVGVFVQLETPIAFDAIDNQ
                     PVDLLFALLVPADQTKTHLHTLSLVAKRLADKTICRRLRAALNDEELYQIITDTEGEQ
                     NEA"
     gene            61595..62449
                     /gene="rapZ"
                     /locus_tag="OPV72_000123"
     CDS             61595..62449
                     /gene="rapZ"
                     /locus_tag="OPV72_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HCR9912544.1"
                     /translation="MVLMIVSGRSGSGKSVALRALEDMGFYCVDNLPVVLLPDLARTL
                     ADRQISAAVSIDVRNIPESPEIFEQAMNNLPGAFSPQLLFLDADRNTLIRRYSDTRRL
                     HPLSSKNLSLESAIDKESDLLEPLRSRADLIVDTSEMSVHELAEMLRTRLLGKREREL
                     TMVFESFGFKHGIPIDADYVFDVRFLPNPHWDPKLRPMTGLDKPVAAFLDRHTEVHNF
                     IYQTRSYLELWLPMLETNNRSYLTVAIGCTGGKHRSVYIAEQLADYFRSRGKNVQSRH
                     RTLEKRKT"
     gene            62446..62718
                     /gene="npr"
                     /locus_tag="OPV72_000124"
     CDS             62446..62718
                     /gene="npr"
                     /locus_tag="OPV72_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS phosphocarrier protein NPr"
                     /protein_id="HCR9912545.1"
                     /translation="MTVKQTVEVTNKLGMHARPAMKLFELMQGFDAEVLLRNDEGTEA
                     EANSVIALLMLDSAKGRQIEIEATGPQEVEALAAVIALFNSGFDED"
BASE COUNT        14687 a        17456 c        16129 g        14611 t
ORIGIN      
        1 gaaagttata aacggagacc actatgttca ttatttccag taaaaatatg ctccagaagg
       61 cccagcatgc aggctatgcc gtgccagcct ttaacatcca taacctagaa accttgcagg
      121 tggtggtaga aaccgccgca gaaatgcgct caccgctgat cgttgccgga acaccaggca
      181 cgtttagcta tgccggaatg ggtaacattg tggcgatcgc gggcgatctg gctcgtgaat
      241 acaatctgcc actggccatt catctggatc atcatgaatc gttagccgat attgaaagca
      301 aagttatggc agggatccgt tcagtcatga tcgatggttc ccactttccc tttgaagaga
      361 atgtggcgct ggtgaaaagc gtggtcgatt tttgccatcg ctacgacacc agcgtggagg
      421 cagaactggg ccgccttggt gggatcgaag atgatttagt ggtagacagc aaagatgccc
      481 tttacaccaa tccacagcaa gcacgtgagt ttgtggcgcg caccggcatt gattcgctgg
      541 cggttgctat cggcacggca cacggtatgt atgccgctga acctaaactt gattttgagc
      601 gactggcaga aatacgcgct ctggtggata tccctctggt attgcatggg gcatctggtt
      661 tgccggaaag cgatattcgc caggccatca gccttggggt atgcaaagtc aatgtcgcca
      721 ccgaactgaa aatcgccttc tccgacgcct taaaagagta tttcctacaa aacccgaaag
      781 ccaatgatcc ccgccactat atgcaaccag caaaacaggc gatgaaagag gtggtacgca
      841 aagtaattca tgtttgcggc tgtgaagggc aactgtgagg aatcgcctgt gatctacacg
      901 ctaacactta atagcgcgat tgatatgaat atatttagcg atcctttaca gccaaatatt
      961 gtcaatcgca ctcaccacac cgagttttgc ccaaatggta aaggggtaaa tgttgcgctg
     1021 gttctggatc actttcaaat acctgcgcat atattaggca tttttggtgg tttcaccggg
     1081 cattatattg tagaaagcct gcgtacccga aaaatgccag tcacaccagc atgggtagaa
     1141 gaacccacgc ggattaatat tttcattcat gacggcaagc aggaatataa actggtcaac
     1201 cctggctcat atattccaga tgaatgtaaa aaacaaatta tcacgattat ttcgcaactg
     1261 cccgatgcag aatatctggt gataagcggc agcctgccac aaggtattga aagtcgcttt
     1321 tacgcagaaa ttatgcatat ttgtcagcaa aaaaatatcg gcgtaatttt agatattagt
     1381 catccgtcat tacgtcagtt actggagttc aaaccgttat taattaaacc aaatgatgaa
     1441 gaggttaaag caatattcgg tttaactgtc tctgacgaca atgatgcgaa aaatactcta
     1501 accactttac atgcacttgg tgcacaaaat gttctgctaa cccttggcgc taaaggaatg
     1561 tatttctcca atgggattga ttactggttt tgtagcgcgc caacggttga tttggtgagc
     1621 tccgcctgtg caggcgatgc tgcactggcc gcctttctca gccagtggtt atctacagga
     1681 gaagtggaat atgccttatc tcttgccagt gcaacaggag ctgatgtcgc aagttctgcc
     1741 ggactaggcc aacttgcggc aatagaaacc ttactttcgc aaatccacgt cagaaagctg
     1801 taggttaaat tacaatataa gttctgctta tgaaaaagat cattgcagtg accggctgcc
     1861 ctaccggtat tgcgcataca tttatggctg aagaagcctt aaaaaatgcc gcgaaaaaat
     1921 tatctgttga aataaaagtt gaaaccaatg gtgccagcgg tgttgaaaat gccattcaac
     1981 ctgctgatct ggtagatatt gccggagtca ttattgcggc ggataaagat gtcttacctg
     2041 atcgctttaa tggtttaccg gttattgaag taccggtaaa agaagcaatc catcatcctg
     2101 cggagctgat taacaaagtt attaatggtg aagccccaat acgtaaaggc gaatcaacca
     2161 ccagcacgga aattatcgaa aaagaatcac tggggcgaca aatttataag cacctgatga
     2221 gtggtgtttc aaatatgcta ccttttgtag ttgccggagg catattaatt gcggtgtcgc
     2281 ttttatgggg gatttattcc gctgatccta attcagctga atacaatgca accgccgcaa
     2341 tgctaatgaa aatcggtcag caagcctttt cgattatggt tccggtcttt accgcttata
     2401 ttgcattctc tatttctggc agaccaggga tggtggctgg gtttgtcggc ggcttactgg
     2461 caaatactac cggagcagga tttctcggtg ggataattgc cggattcgcc gccggttacc
     2521 tgatgttatg ggtaaagaat cgactcgaag gcttaccgcg tcagtatgaa ggcctgaaat
     2581 cgatttttat tatgccgctc attggcgtac tggttattgg cgtgttgatg tcgctgcttg
     2641 ggcaacctgt cgcagctatc aataatagca tgatgaactg gctggcatcg ctacaggaag
     2701 cgaatccaat attgctgggt attgtggtgg gtgcaatgtg ctcttttgac tttggcggcc
     2761 cggtaaacaa agccgcttat gtcaccggca cgcttttact gggccagggc aacttctact
     2821 ttatggctgg tgtgtctgcc gcatgtatta ctccaccact ggtaattgct ctggcgacca
     2881 ccttctttcc aaaaggtttt agcgaggaag aacgtgccgc aggcatggtt aactatatcc
     2941 tcggttgtac acacatcact gaaggcgcga ttcctttcgc agcgaaagat cctttgcgtg
     3001 tcatcccgat gatgatgatt gcttccagca tttccgcagt acttagctac agcttgcgta
     3061 ttcaggttcc ggctcctcac ggcggcttct taattttacc tttggtgagt cagccgctgg
     3121 cctgggtgtt atgtatcctt gcgggatctg catgtggtgc gatgatgctt ggcctatgga
     3181 gattgtgggc tgtgcgcaaa aattcagtca acacaactcc tgtagcaaag gctggaggtc
     3241 agaatgcagc tctgtgaaca cgatattttt atcagcgatg agcgcctcga taaagtcacc
     3301 gctctgcacc gcgtggtgga aaagttatct gcggctggca ataccacgcc tgactattta
     3361 cgcggcatgt tggatcgcga agcacagatt tccacttatc tgggaaatgg aatcgcgatc
     3421 ccacacggta cgccagaatc tcgcgatgcg gtattacaaa ccggtgtaaa ggtaatcgtt
     3481 tttcgccacg gcgttgactg gggtgacggc aataccgcgt atctggtcac cggaattgcc
     3541 gcgcgctcca atgaacatct tgagattttg cgccaactga ctcgcgtgct cagcgatgac
     3601 gctattctgc aagcactggc taaagccgaa tcccccagtc aggttttagc gctactgact
     3661 ggctcgacga ccaatacgcc agcagccatg gagttgcacg agggtgagca ggcaacattt
     3721 gtcatccata atccgcatgg tttacatgcc agacccagtg cggtactggt gaagtttatc
     3781 aaacagtttc aaagccacat tacggtagaa aatctggata acgcctccgg cccggtggac
     3841 ggaaaaaacc tgatgcgagt ggtgtcgctc ggcgcgaaaa aggggcatcg cttgttgttc
     3901 cgggcgcagg gcgaagatgc acagcaggca ctacgtgaaa tcggggagct tatcgcctct
     3961 ggtgcaggcg agatgatcac cgttcccgtt accccaccac cagaagtcat gcagccaaag
     4021 cgcagttggc tatctcgatt gtttaattag ccttcatttg ttcctccgtg cccgctccgg
     4081 cgggtacggt ttttcatgac aaagtgaagt tacagacatt acacaccatt tcgttacctt
     4141 acattttctt tcgcaacttt catttatcag atcaaaatca caaaacaaca ttacgaaagc
     4201 ctataaattc tttcgaagaa taaaaacgaa agaactcgga gataaaagtg aaagaaataa
     4261 ttgctcgtca taaagcagga gaacatctgg gcatctgttc agtttgttct gctcatcccc
     4321 tggttatcga atcagctctg cttttcgatc tcaatactga caacaaggta ttgattgaag
     4381 ccacatccaa tcaggtgaat cagtttggcg gttataccgg aatgaaaccg gctgattttc
     4441 gtgattttat ttatggcatt gctcaggaag tgggatttcc acgtgagcgg ttgattcttg
     4501 gtggcgatca tttagggcct aactgctggc agaacgaacc ggcagcggcg gcaatggaaa
     4561 agtcggttga gttaataaaa gcgtatgtcg ccgctggttt tagcaaaatt cacctggacg
     4621 cgtcgatgtc ctgcgctgac gacccgacac cgttggatcc gatggtcgtt gcacgccgtg
     4681 ccgccgtgct ttgtaaagca gcagaagaga ccgcaaacga agaacaaaaa tgccatctga
     4741 cttatgtcat cggcacggaa gtgcccgttc ctggcggtga agccagtacc atcggcagcg
     4801 ttcatgtcac ccgcgaggtc gatgctgccc gtacgctgga aactcaccaa atcgcgtttc
     4861 gtgaatcagg tctggaagaa gcactgtcac gcgtgatcgc cattgtggtg caaccgggcg
     4921 ttgaatttga tcatacccag attattcatt atcagccgca ggcggcacag gcgctctccg
     4981 catggatcaa agaaacgccg atggtctatg aagcgcattc gactgattac caaactcgcc
     5041 aggcctaccg cgccctcgtt cgcgatcatt acgccattct gaaggtcggc cctgcactca
     5101 ctttcgccct gcgcgaagcc attttcgcac ttgcgcaaat ggaaaacgag ctgatctccc
     5161 cggaacaacg tagccgcgtg atggaagtta tcgatgaagt gatgctaaac gagccaggct
     5221 actggaaaaa gtactaccgc cccacctaga gccaggcgat ggtcgacatc cactttagtt
     5281 tgtctgaccg tattcgctat tactggccgc acccgcgtat tcgtcaaagc gtagagaagt
     5341 taatcgccaa tctgaataac gtcacattgc cgctgggatt aattagccag tttatgcccg
     5401 tacagtttga acgcctgtct gagggcgtgc tcacccccac gccgcataac ctgattattg
     5461 acaaaattca ggatgttctg cgcgcttatc gcttcggttg cacgccggat gtcgcctgaa
     5521 tagtggagaa tttatgagcc aattatttgt ccgaaccgga atcacattcg actcgagcca
     5581 acaggcgctg gcgcacattg gcaaagagat gctggcgaaa ggcgtggtac atgatagtta
     5641 tccgcaggca ctggtggaac gtgaagcgtc ctttcccacc ggcattgcgc tggagcgcca
     5701 cgccgtcgct atccctcatt gcgaggcagt tcatgcgaaa tcacccgcta tctatctgat
     5761 tcgtccagat aagccggtca tgtttcaaca ggcggatgat gacgaagaga ttgccgtttc
     5821 gttaatcatc gccttaatcg ttgaaaaccc ggcggcacag ctaaaacttc tgcgccgtct
     5881 gttcggggca ttacaaatcc cggacaccat agaagcctta ctgagcgccc cggatgccga
     5941 actggcgtcg tgctttgagc acaaagtcct tacggctgag cagtgcgtcc aggtttaata
     6001 ataaattgat aataatgagg aataccctat gaaacgtaaa gtaattgtgg cctgtggcgg
     6061 tgcggttgca acctcaacga tggctgcgga agaaattaaa gagctatgtg atgccaacca
     6121 tattgagctc gacttagtgc aatgccgggt caccgaaatc gaaacctata tggacggcgc
     6181 cgatcttatc tgtaccactg ccagggtcga tcgcgccttt ggcgatattc ccgtcgttca
     6241 cggtatgcct tttgtttccg gcgtgggtat tgaagcatta cagcaaaaaa ttctgtccat
     6301 tctcatgggg taacgtatgt ttagcgaaat aatgcgttat atcctcgact taggcccaac
     6361 ggtgatgttg cctctggtga tcatcgtgtt ctctaaactg ctgggaatga agcttgggga
     6421 ttgttttaaa tcgggtttgc atattggtat cggcttcgtg ggtattggtc tggtcatcgg
     6481 cctgatgctg gattctatcg gccccgcggc gaaagccatg gcggaacatt tccaaatcaa
     6541 tctccacgtt attgacgtcg gctggccggg ttcatcgccc atgacctggg cgtcacaaat
     6601 cgcgctggtc gcgatccctg tcgccatcgg ggttaacgtc ctgatgctgg tgacccgcat
     6661 gacccgcgtg gtgaatgtcg atatctggaa tatctggcac atgaccttca cgggcgccat
     6721 gctgcatctg gcgaccggtt catactggct ggggattctg ggcgttgtgg ttcatgccgc
     6781 ctttgtctac aaactggggg actggtttgc caaagatacc cgcgactatt ttggcctcga
     6841 ggggattgct atcccacacg gctcatccgc gtacctgagc cccgtggcgg tgctcgttga
     6901 taccattatc gagaaaattc cgggtctcaa tcgtattcac tttagcgcag acgatgtcca
     6961 gaaacgcttc ggaccgtttg gcgagccggt gactgtcggc ttcgtgatgg ggctggtgat
     7021 tggtgtactg gcaggctacg acaccaaagc cgttctgcaa ctggcagtca aaaccgcagc
     7081 ggtgatgctg cttatgccac gcgtcattaa acctattatg gatggcctaa cgcctatcgc
     7141 caaacatgcg cgtaaacgtc tacaggccaa atttggcggg caggagttcc tgataggcct
     7201 tgatccagcg ctactgctcg gtcatacctc tgttgtctcc gcgagcctga tattcattcc
     7261 gctgaccatc ctgattgccg tcttagtacc ggggaaccag gtgctgccgt tcggcgacct
     7321 cgccaccatc ggtttcttta ttgcgatggc ggttgcggta caccagggca acctgttccg
     7381 cacgctgatt tcaggtgtca ttattatggg tatcaccctg tggatagcca cgcagacgat
     7441 tggcctgcat acccaactgg ctgccaatgc cggagcgcta aaagctggcg cacaagtcgc
     7501 ctcgctggat cagggcggtt ctcccatcac ctggctgctg attcaacttt ttacctggca
     7561 gaatatcgtc ggcttcgccg tcattgccat tatctatctg gccggcgtac tgctgacctg
     7621 gcgtcgcgcc cgacagtttg tcgcggctga gaaagccacg gcgctacagc aaagtcaaat
     7681 cgcctcttaa ttttagggga gcaatcgctc ccctcacctt cctggagaat gttatgaaat
     7741 cagtggttat tcacgctgag ggagacgtgc gcgttgaaga acgtccctta ccacaactgc
     7801 aagccgagga cgatgtgttg gtcaaagtcg ttagctcagg gctttgcggg tcggatatcc
     7861 cgcgtatttt cgcgcagggc gcccattatt atcctattac gttaggccat gaattcagcg
     7921 gctacgttga atcctacggc acaggcgtaa cggatatgca gcctggcgat gccgtcgctt
     7981 gtgtcccgct tcttccctgc tttcactgtc cgcaatgcga acgcggttac ttttctttat
     8041 gcaaacagta tcagtttgta ggatcgcgca gcgaaggcgg taatgcggaa tatgtggtgg
     8101 tcaaacgggc caatcttttc cgcttgccgt ctgatatgcc gattgaagat ggcgcgttta
     8161 tcgaaccgat taccgtgggc ttacacgcct ttcatctggc gcagggctgc gaggggaaaa
     8221 acgtaattat cgtcggggcc gggacaattg gcctgctggc cttacagtgc gcgcgggaac
     8281 tgggcgcgcg aagcgtaacg gcgattgata tcaatccgca gaaactggaa ctggcgaaag
     8341 cgctcggcgc aacgcatacc tgtaatagcc gggaaatgac cgccgacgac atccagaccg
     8401 cgttgtccga cattcagttt gatcaactgg ttctcgaaac ggcaggaact ccccagaccg
     8461 tctcgctggc tatcgatatc accgggccgc gcgcgcaact ggcgctggtg gggacgttac
     8521 atcacgatct caccctgacg acgcgtacat tcgggttaat tttgcgtaaa gagctcacgc
     8581 tcctcggcag ttggatgaac tactccgcgc catggccagg agaagaatgg gaaaccgcag
     8641 cgcgcctgtt ggctgaaaaa cgtcttcaac tgacccctct cattgcccat cgcggcgatg
     8701 cggaaagctt tgcagaagca gtcaaagcgc ttaatggcgc gcccatgcag ggcaaaatct
     8761 tacttcaact ttcctgatgg tacgagccag caacctgcgc tggctcacat ttcctttcga
     8821 aatttagcgt tcacctttcg caatccttcg tttaaactag ttacagttaa ttatcaggca
     8881 aatcaatatg aactcatttg agcgaagaaa taaaattgtc gacctgatta atacgcaagg
     8941 cagcgtgctg gtgatggacc tttcaaatac ctttggtatt tctgaagtga ctatccgtgc
     9001 tgacctgcgt ctgctggaag agaaaggcct tgtcacccgt tttcatggcg gcgcggcaaa
     9061 accgggaagt catctggcgg aaggcgacaa tcaggaagtc attctggaag atcggtatca
     9121 actcgccagc gatccgaaaa agcggattgc ccaggcggct gcggcaatgg ttgaagaagg
     9181 aatgaccatc attctggata gcgggagcac aacattacta attgcggaag cgctcgcgcg
     9241 aaaaagcaat attacggtga tcactaacag cttgcctgcc gcttttacgc tatcagaaaa
     9301 taaagatctc acgctggtgg tttgcggcgg tacggtacgg cataaaaccc actcaatgca
     9361 cggcacgatt gcggaacgat cgctacacgg catcagcgcc gatgtcatgt ttgtcggggc
     9421 ggatggcatt gatgcgacaa acggtattac cacgtttaac gaaggttatt ccattagcgg
     9481 cgtcatggcg gcggcggcgc acaaagttat cgcggtactg gacgcgacca aatttaaccg
     9541 tcgcggcttt aaccaggtat tgccgatgga caagatcgac tgtgtgataa ccgatgacac
     9601 catcagcaaa caggataaag cggcattagc gaaaacaggc gtggaattaa tgatcgtcta
     9661 aaaaggagtc ggttatgcat tgctgatcgc gagagtaagc ccaaaggaaa ggtccggccc
     9721 gctatcaccg cccaatgccc ccatcacttt acccacatca atcacctgat tgagtattaa
     9781 cgtgatggcg ataaaaggcg gttcccgggc gctcgctttt actcttcctg ctgcgccagc
     9841 gcatacttat acagcgcatt tttcttcacg ccgtgaattt ctgctgccag cgccgccgct
     9901 tttttcagcg gcagctctgc ctgtagcagc gccagcgtgc gcagcgcgtc ggcgggcagg
     9961 tcgtcttctt gcgctttatg cccttcgaca atcagcacca tttcgccttt gcgacggttt
    10021 tcatcttctt tgacccacgc cagcagctcg ccgaccggcg cgccgtgaat ggtttcccag
    10081 gttttggtca gctcacgcgc cagcaccacg taacgggatt cgccccacac ggccaccata
    10141 tcttccaggc tatccaacag acgatgggtg gactcataaa aaatcagcgt tcgtggctcc
    10201 gcttcaatgg cttttagcgc atcacggcgg ccttttgatt tggcaggcag gaagccttca
    10261 taacaaaaac gatctgatgg taaacctgcg gcgcttaatg cagtgatagc agcacacggc
    10321 cctggtagcg gcaccacgcg aatccccgct tcacggcagg tacgtaccag gtgatagccg
    10381 gggtcattaa ttagcggcgt tccggcatcg gaaaccagag caatgttctg cccctctttc
    10441 agcttcgcga ccagcgtttc cgctttttgt tgttcgttat ggtcgtgcag cgcaaacaac
    10501 cgggcattaa tcccaaaatg ttgcagcaat aaaccggtgt gacgagtgtc ttcagcggca
    10561 attaaatcaa cggcttgtaa aacttccagc gcgcgttggg taatatcagc caaattcccg
    10621 ataggagtag gtacaataaa gagttggccc tgagaattat ccgccgattc gttttgtttc
    10681 attgtgtcgt ccgtattgcc gatttaatat tgagcattgc gtaaaaaaat atcactggat
    10741 acagtatggt accctcaaca ttttctcgtt tgaacgccgc gcgcgcgctg cctgtcgtcc
    10801 tggctgcgct acttttcgcc gggtgcggca cccaggcgcc agatcaaagc gcagcctata
    10861 tgcagggttc agcgcaagct gattccgcct tttacctgca tcagatgcag caaagcgcag
    10921 atgatagcaa gaccaactgg caattactcg ccattcatgc actgctgaaa gaaggaaaaa
    10981 gccagcaggc cgtcgagttg ttcaatcaac ccccgcaaaa tctgaacgat acccagcgtc
    11041 gcgaacaatc tttattagcg gtagagatca aactggcgca gaaagatgtg gcaggcgcgc
    11101 aggccttgct ggataaacta aaacccgccg actttgcgcc acatcagcaa gcgcgttact
    11161 ggcaggcgca gatcgttgcc agccagggac gcccgtcgct taccctgttg cgggcgttaa
    11221 tcgcccagga accgctactg gcggcgaaag agaaacaaaa aaatatcgac gccacctggc
    11281 aggcgctctc cgccatgacg ccggatcagg ccaggacgtt agttatcaac gccgatgaaa
    11341 atgtgcttca gggctggctg gatctgcaac gcgtctggtt tgacaaccgc aacgatccag
    11401 acatgctgaa agccgggatc gccgactggc aaaaacgcta cccgcaaaat ccgggggcga
    11461 aaatgctgcc gacgcagctc gtcaatgtac aacgttttaa accagcttcc accagcaaaa
    11521 tcgctctgct gctgccgctg aacggtcagg ctgccgtgtt tggccgtacc atccagcaag
    11581 gtttcgaagc cgcgaaaaac ctcggcaccc aggcggtgga aatgcagcct gtcgccgcgc
    11641 ctgacgcgcc ggtcgaacca agcgtggagg agacgcaacc acaaatgacc aacggcgtcg
    11701 ccagtccgtc gcaggcctcg gtgagagatc tgactgatga cgctccatcc cagtctgcta
    11761 cgccagtcag cgcgccacaa actccccctg cgcagcctgc tacagcaagc gcgccggcgg
    11821 atccctccgc tgaattaaaa atctacgata cctcttccca gccgttggat caggtgctcg
    11881 ctcaggttca gcaagacggc gccagtatcg tggtcgggcc gctgttgaaa aacaatgtgg
    11941 aagcgctgat gaaaagcaac acgccgctca acgtgctggc gctcaaccag ccggaaacgg
    12001 tacgtagctt ccctaatatc tgctatttcg cgctctctcc agaagatgaa gcccgtgacg
    12061 cggcgcatca tatttatgag cagggcaagc agtcgccgct gctgttgatc ccacgcagcg
    12121 cgcttggcga tcgcgtggcg aatgccttca cccaggagtg gcaaaaactg ggcggcggca
    12181 tcgtgttaca gcaaaaattc ggctccgtag ccgagctgaa aatgggcgtg aacggcggcg
    12241 cgggtatcgc gttgacgggc agtccggtcg ccgccagcgt gcctgcgcag ccgggcgtta
    12301 ccattggcgg tctgaccatc cctgcgccgc cgaccgacgc gcaaatcacc ggcggcggac
    12361 gcgtagacgc ggtctatatt ctggctacgc cggaagagat tggctttatc aaaccgatga
    12421 tcgccatgcg taacggcacc cagagcggcg cgacgctgta tgccagctcc cgcagcgcgc
    12481 aaggcacctc cggccctgac ttccgtctgg agatggaagg tttgcaatac agtgaaattc
    12541 ccatgctggc aggcggcaat acgccgttga tgcagcaggc gctgagtgct gtacataacg
    12601 actattctct ggcgcggatg tacgccatgg gcgtggatgc ctggacgctg gcgaaccact
    12661 tttcgcagat gcgtcaggtg caggggtttg agatcaatgg taataccggc gcattaaccg
    12721 ccagcccgga ttgtgtgatt aacaggaagt tatcatggct caaataccag caaggggaga
    12781 ttgttcccgc cagctaacac gtaaacaggc tggcgacgcg tgggaagctg ccgcgcgtct
    12841 ctggctggaa agcaaaggac tgcggtttat cgccgccaac gtgcgcgagc gcggcggcga
    12901 aatcgatctg atcatgcgcg acggaaaaac gacggttttt gttgaggttc gctatcggcg
    12961 ctccgggctt tatggcggcg cggcggctag tgtgacccgc agcaagcaac acaaattatt
    13021 acatactgcc cgcttgtggc tcgcccgcca gaatgggagt tttgatactg tggattgtcg
    13081 gttcgatgtg ttagccttca ccggaaatga gattgagtgg tttcgggatg cgtttaacga
    13141 ccactcataa ttgaagattt taaggattag cgtgctcgaa agaatcaaag tttgctttac
    13201 agaaagcatt caaactcaaa ttgctgcggc ggaagcgctt ccggatgcca tttcccgcgc
    13261 cgccatgacg ctggttcatt ccctgcttaa cggcaacaaa atcctctgtt gtggaaacgg
    13321 gacgtccgcg gccaacgcac agcattttgc tgccagcatg attaaccgct ttgaaacgga
    13381 gcgacccagt ttacccgcca ttgcactaaa taccgataat gtggtcttaa ctgcgatcgc
    13441 taacgatcgc ctgcacgatg aagtttatgc aaaacaagtc cgggcgctgg gacatgcagg
    13501 cgatgtttta ttggcgatct ctacgcgtgg taatagtcgc gatatcgtaa aagccgttga
    13561 agcagccgtc acacgtgaca tgaccattgt ggcgctaacc gggtatgacg ggggcgagct
    13621 ggccggacta ttagggccgc aggatgttga aattcgtatc ccttcacacc acagcgcgcg
    13681 cattcaggaa atgcatatgc tgacggtaaa ctgcctgtgc ggtttgatcg ataacacgct
    13741 ttttcctcac caggatgatt aaggagtaca catgaaggca ttttcgccgc tcgcagtcct
    13801 tatttctgcg ttgctattgc aaggttgcgt cgccgccgcg gtagtgggta cggcagccgt
    13861 cggcaccaaa gccgcaaccg acccgcgtag cgtgggcacc caggtggatg acggaacgct
    13921 ggaactgcgt gtcagcagcg cgctgtcgaa agatgagcaa atcaaaaaag agacgcgcat
    13981 caatgtcact gcttatcagg gcaaagtttt gttagtgggc cagtcgccaa acagcgaact
    14041 ctccgcacgc gcgaaacaga tagcgatggg cgttgaaggc accaccgagg tctataacga
    14101 gattcgccag ggtcagccta tcggcctggg gaccgcctct aacgatacct ggatcaccac
    14161 gaaagttcgc tcacagctac tgaccagcga tcaggtaaaa tcgtcaaatg tgaaagtcac
    14221 caccgagaat ggcgaagtgt tcctgctggg cctggtgact gaacgtgaag gtaaagcggc
    14281 agcagacatc gccagccggg tgagcggcgt gaaacgcgtg accaccgcct ttacgtatat
    14341 taagtaaccg gtgtgccggg tggcgataaa aatgtgtaaa tcgcgtcgcc atccggtaaa
    14401 tcatccggct tcgctacccc gctttttccc gcagttgcga tgaggtcaga atcgtcacgc
    14461 cttcttgtgc tggctccagc gcttccgcca gcatggcccg cgccacatcc cgcgcatcga
    14521 tcgatttcca gtttcctggc agcagccgga atagcggagc gaaaagcgtt tcattcaccc
    14581 gccgcgttgt tctgtcgccg agcagcatag aaggccgggc aatcgtcaaa cgaggccaat
    14641 tttgcgcgat taacgcctcc tccatttctc ctttcacccg attgtagaaa aacggagagt
    14701 gcgcgtttgc tcccattgcg ctgaccacca acatgtgctg cgcgcccagt cgacgcccgg
    14761 tcagcgcggt atcaaccacc agcgtataat ccgcatgaat aaacgccgct ttacttcccg
    14821 cttcacgccg ggtcgtgccc aggcagcaaa aaacaatatc caccgggtcg gtcacctgag
    14881 ctaacgcgtc ggtaagctgc ggatcgtgag ggttataaac gccgacaata tccgtcagcg
    14941 ggcgacgcgt tggcgcggcg atcgcgctca cctgcggcgt gttgattaac attctcagca
    15001 gatgtccgcc gaccagtccg gtcgcgccgg taatcagtac ctgactcatc ctcgctcctt
    15061 tacagatttg tccaccttgc actctcggcc ctatcgacca ggcttaatag tctacgaggt
    15121 aagtatccat cattgtggaa aatttgcctt acccgacgcc accactgcgg aggaaacgca
    15181 tgagtaagaa aattgccgtt ttgattaccg atgaatttga agattcagaa tttacctcgc
    15241 cggctgcaga attccgtcag gccggccatg aggtcatcac catcgaaaaa gaggcgggta
    15301 aaacggtgaa aggaaaaaaa ggcgaggcca gcgtcaccat tgataaggct attgatgacg
    15361 ttcgtcccga cgagttcgac gccttgctat tgccgggagg tcattcgccg gactacctgc
    15421 gcggcgacag ccgtttcgtg gattttaccc gcgatttcgt taacagcggt aaaccggttt
    15481 ttgccatttg ccacggcccg cagttgttga tcagcgccga tgtcattcgt ggccgcaaac
    15541 tcacggcggt gaaaccgatt attatcgatg tgaagaatgc gggcgcggaa ttttacgatc
    15601 aggaagtcgt cgtcgataaa gatcagctgg tgaccagccg cacgcctgac gacctgccgg
    15661 catttaaccg cgaggcgcta cgcctgctgg gcgcgtgagt cacgtaacca gtgcagtttt
    15721 ttaccaaacc ccagcgtgtt gtcggtgaat ttaatttcat ccagccgaat ttcccatacc
    15781 ggcgctggca gcaccctggc gaccgggaag cgacgaaggt aagctttacg cgcggcgtcg
    15841 ctctcctgcc cctccagacg gcgaatttcc cctttaaact gcacgccgcg aatgcgcgcc
    15901 accgttttcg gctgaccatt gaccgttccc gcaactggcg cgcacgcgcc ggacatttgc
    15961 gcatggcggg ttttatcatc cgttaacaga tacagcgcga cgttttgcgc atcgaacaaa
    16021 taaaacgcat tggcgcacca cagctctccc tcatggtgta cgcaccaggt caccacgtgt
    16081 tgtttcgcca gccaacggcc aatagcggta agtgtgtcca tctttattct cgcttatact
    16141 gggaacctga aaattatcat gctgatggcg acaatgacac cctggtatct gtatctgatt
    16201 cgtactgcag acaatgcgct ttacaccgga ataaccaccg atgtggcgcg tcgttacagg
    16261 cagcatcaaa cgggaaaagg cgcaaaagca ttacggggaa aaggcgagtt aacgctggcg
    16321 tttgcggcgc aggtcggcga tcgctcgctg gccctgcgca tagagtatcg catcaaacag
    16381 ctcacaaagc gccagaagga gcgccttgtg acggaacgcg aagcgtttga ggcgctgctg
    16441 tccagcctgc aaacgccggt gcttaaaaac gattgaagtg gtcgtgatac tccaccagcc
    16501 ccgtcacgcc ctccagcgca tcctcagcca aacggtgtac ctggaaagcg ctttccgtac
    16561 cgggccaacg gcagtgaaga tcgtaatgtg cggccagttc aaaaccgaag cggctatata
    16621 acgccgggtc gcccagcgtc acgaccgccg cgtagccgaa ctcgttgagc gaatccagcc
    16681 cttcatacac taactggcgc gccagccctt gcccgcgata cttttcatcg accgccagcg
    16741 gcgccatgcc gacccactgt aaatcttcgc cctgcacatc aaccgggcta aaggcgacat
    16801 agcccactac ctggccttca tcatccgtgg ccaccagtcc gagcgtcaga aaaccatctt
    16861 cacgcaaatc gtgaaccagc ttcgcttccg catcgctttc gaatgaacgg cgtaacagcg
    16921 catcaatacc aggcgcatca atgggaattt ctactcgaat tagcatggtt cacctaccga
    16981 ggtctgtttg gtttccggcg agtttttcat tcccgcctca acaaaatccg ccagttgcag
    17041 cagcataatg cgtaacgctt tcggcatctg ctccagttcg atggcgtcca tcagattctt
    17101 cacatacaac cctaactcag tatcgccttc aatgaccagt cgacgctgga aaaagagcgt
    17161 atccggatcc tgtttacggg cggcgatcat tagcagatcg ctggcgtcgg cgctaaaact
    17221 gacgtcagca tccgcctgct ggctaacgat cagcttttca ttttcaaccg tggtatacca
    17281 ttttaagtcg atgtcacgaa catgaatgct taaccaacga ccttcgagga attccagctc
    17341 tccatcggcc agcgcctgac gaaactgcca gctcagaacc tgttccagaa cctggcgctt
    17401 tagcgcaaag ggcgtcagtt taaccggtac actcatcaga gacgggccag catggactaa
    17461 gcgtgaacgc agtttatcta acacgagctt tactccctgt ttcaatagtc ctgttatttt
    17521 gccatatcca ataaatcaca tggcggcgta aatcaacaat tgggtctgat tttctacccc
    17581 attattggtg ttaccaatac gcctttaact gccttaaatc aaaaattgtc gcagcaaggt
    17641 taactaaaat ccctgttcgt taacaatttt gcgtcgcaga cgtaaccctc aggataaatt
    17701 atggagctgc tctgccctgc cggaaatctc ccggcgctga aggcggccat cgaaaacggc
    17761 gctgacgccg tttatatcgg gttaaaagac gataccaatg cccgtcattt tgccggcctt
    17821 aactttaccg aaaaaaaatt gcaggaagcg gtgagttttg ttcaccagca tcgccgcaaa
    17881 ttacacatcg ccattaatac ttttgcgcat ccggacggct atgcccgctg gcagcgcgcc
    17941 gtggatatgg cggcgcagct tggcgccgac gcgctgattc ttgccgacct cgctatgctg
    18001 gaatatgccg cagagcgtta cccgcatatt gagcgccatg tttccgttca ggcctcggca
    18061 accaacgaag aagcgattcg cttttatcac cgcaactttg atgtccaccg tgtagtactg
    18121 ccgcgtgtac tgtcgattca ccaggtaaaa caactggccc gcgtcacgcc ggtgccgctg
    18181 gaggtattcg cgtttggcag cctgtgcatt atggcagaag gtcgctgcta tctttcttct
    18241 tacctgacgg gggagtcgcc caataccgtc ggcgcctgct ctcccgcccg ctttgtccgt
    18301 tggcagcaaa cgccgcaggg gctggaatcg cgcctgaatg atgtcctgat tgaccgttac
    18361 caggatggcg aaaacgcagg ctacccaacg ctgtgtaaag gccgctattt agtggacggc
    18421 gagcgctatc acgcgctgga ggagccaacc agcctgaaca cgctggaact gctgccggag
    18481 ctcatggcgg cgaacatcgc ttcggtgaag atcgaaggcc gccagcgcag cccggcctac
    18541 gtcagccagg tggcgaaagt gtggcgccag gcgatagatc gctgcaaagc cgccccgcaa
    18601 aacttcgttc cacagcgcga ctggatggag acgctcggcg cgatgtccga aggcactcaa
    18661 accacgcttg gcgcatatca ccgtaaatgg cagtgagagg agctatgaaa tattccttag
    18721 gaccggtgct ttattactgg ccgaaagaga cgctggaaga tttttatcag caggccgcaa
    18781 aaagcagcgc tgatatcatt tatctgggcg aagcggtgtg cagcaaacgt cgcgcgacta
    18841 aagtcggcga ctggctggaa atggcgaaat ccctcgctgc cagcggtaag caggtggcgc
    18901 tctccaccct ggcgctggta caggcgtcat ctgaattaag cgagctgaaa cgctatgtgg
    18961 acaacggcga ttttctgctg gaagccagcg atcttggcgt ggtgaatctg tgcgccgagc
    19021 gcaaactgcc gtttgtcgcc ggccatgcgc tgaattgcta caacgcggtc acgctgcgcc
    19081 ggttgctgaa agaaggcatg gtacgctggt gtatgccggt ggagctctcc cgcgactggc
    19141 tggtgaattt gcttaatcag tgcgatgaac tgggcatccg caatcagttt gaagtggaag
    19201 tgttgagcta cgggcatctg ccgctggcct actccgctcg ctgctttacc gcccgttcgg
    19261 aagaccgccc gaaagatgaa tgcgaaacct gctgtatcaa gtatccaaac ggtcgtgacg
    19321 tgctctcgca agagaatcag caggtgtttg tgcttaacgg tattcagacc atgagcggct
    19381 atgtctataa ccttggcaac gaactgacgt cgatgcaggg attggtcgat atcgtgcggc
    19441 tgtcgccgtt ggggacggag acatttgcca tgcttgatgc ctttcgcgct aacgaaaacg
    19501 gcggcgcgcc gttaccgctt gccgcccata gcgactgtaa cggctactgg aagcggctgg
    19561 ccgggctgga gctacaggcc tagccggatg gcagcatcaa taccttatcc ggcctacaaa
    19621 tagcgctccc gaaggcccga taagcgcagc gccatcgggc attgtttttg ccattagtct
    19681 cataaagctc actttgttaa caacattcgc taatctttaa tgcagtatta aaagattaat
    19741 cggtaacaaa gtgagccgtt atgactgaca aaactattcc gttctcggtg ctggatctgg
    19801 cgccgatccc tgaaggatct tcggcaaaag aagccttcac gcactcgctt gatctcgcac
    19861 ggctggctga aaagcgtggc tatcaccgct actggctggc ggaacatcac aacatgaccg
    19921 gtatcgccag cgcggcgacc tcggtattga ttggttatct ggcggccaat accacaacat
    19981 tacatcttgg ctccggcggc gtgatgctgc ctaaccattc accgctggtg attgccgagc
    20041 agttcggcac gctgaatacg ctctacccgg gacgtatcga cttaggattg ggacgcgcgc
    20101 cgggtagcga tcagccgacg atgcgcgcgc tgcgtcgcca tatgagcggc gatatcgata
    20161 actttccacg cgatgtcgca gagctggtgg actggttcga cgctcgcgat cctaatccgc
    20221 atgtgcgccc ggtgcccggc tacggcgaga agatcccgat ctggctgttg ggctccagcc
    20281 tgtatagcgc gcaactggcg gcccagcttg gcctgccgtt cgcctttgct tcgcatttca
    20341 cgccggatat gttgttccag gcgctgcatc tgtaccgtac tcagttcaaa ccttcagcgc
    20401 ggctggaaaa accgtacgcg atggtgtgta tcaatattat cgccgccgac agcaaccgcg
    20461 acgccgaatt cctgtttacc tccatgcagc aggcttttgt gaagctacgc cgtggagaaa
    20521 ccggccaact gccgccgccg attgagaata tggaaacctt ctggtcgcca tccgagcagt
    20581 atggcgtgca gcaggcgctg agtatgtcgc tggtcggcga taaagcgaaa gtccgccacg
    20641 ggctggtgtc cattctgcgg gaaacccagg cggatgaaat tatggtaaac gggcagattt
    20701 tcgaccacca ggcacgcctg cattcgtttg atttagcgat ggatgtgaag caggaattgt
    20761 tggggtagcg cattgttttg cccggtggcg cttcgcttac cgggcctaca gcatcaagta
    20821 ggccggataa ggtgcaaccg ccatccggca caataacgtt actggtacac cggcagcaaa
    20881 ttaaagctcg acagaatatg gataaccgcg ttgccgacac cgaagaccag aatcagggca
    20941 atcatcggtt taccgcccca gacgcgaaat tttgggctgc cgaaacgttc gcgagatttg
    21001 cgcgccaaca gcgcaggcac aatggccgcc cagatagttg cagctaaacc tgcatagcca
    21061 atggcgtaca gaaaaccgtt cgggtacagc aggccaccaa tcatcggcgg caggaaagtc
    21121 agcagcgccg ttttaaaacg tcccattgcc gagtcatcaa aaccaaacag atccgccaga
    21181 tagtcaaaca gccccagcgt cacgccaagg aaggaactgg cgaccgcaaa gttagagaac
    21241 accaccagca gcagatccag gctgcggctg ttcagcacgc cgctcaacgc ctgtaccagc
    21301 acatcaatat tgccgccttt ctgcgcaatg ccgataaatt ccggacgtgg gatgttgccc
    21361 atcgtcccca gcagccagac ggaatagagc gccagcgcca gtaacgtccc ataaatcagg
    21421 catttcacga tggtgcgcgg atctttgccg taatatttca tcaggctcgg tacgttaccg
    21481 tgataaccaa aagaggccag acaaaatggc agcgtcatca gcaggtacgg cgtatatgac
    21541 gcgtggcttt cagccacgtt aaacaacgtg gtcggctgaa cgtgccctaa caggctgccg
    21601 aaggtcagga agaaagtaat cactttcgcg cccagcacaa tcgccgtcat ccggctgacc
    21661 gccttcgtac tcagccacac gacaaacgcc accagcagcg caaaggcaaa acctgccgct
    21721 cgcgccggaa cgttcagcga catctcagca aaggtatgat gcagaattga gccgctcgcc
    21781 gagatatagg cgtaagtcag gatgtagagc acaaaggcaa tagagatgcc atttaccacg
    21841 ttccagcctt tccccaacag atctttggtg atggtgtcga aactcgaacc aatgcggtag
    21901 ttaaggttag cttcgaggat catcagcccg gagtgcagca tacaaaacca ggtaaagacc
    21961 agcgccgcca tcgaccagaa gaaccacgcc ccggacatga ccaccggcag ggagaacatc
    22021 cccgcgccaa tgatggtgcc gccgataatc accacgccgc caagcagcga aggtgacgtt
    22081 tgggtggtgg taagtgttgc cattcagctc tctctccagt catttatagt gtgactatct
    22141 ctcaatacgt tgcactgtac cagtacacga gtacaaaaga aataaaaaaa gccccgattg
    22201 tgacgatcgg ggctgtatat tttactttac gctgtgaatg cgcaggtcag cgtgagttac
    22261 gcatcaccgc cgaaacgacg gcgaccggta gagtcatcac gacgcggacc acggctttca
    22321 cgacgttcgc cgctgaagcg acgaccatca ccacgaccac cttcacgacg ttcgccgctg
    22381 aaattacgac cgccttcacg acgttcgcca ctgaagctac gaccaccgcc gcgacgttcg
    22441 ccgcccgcgt gcggaaccgc atcacccaac agctgcatat tcatcggctt gttcagaatg
    22501 cgagtacgcg tgaagtgctg gagcacttcg cccggcatac ctttcggcag ctcgatggtg
    22561 gagtgagacg cgaacagctt aatgttacca atgtaacggc tgctaatgtc gccttcgtta
    22621 gcgatagcgc ccacgatatg acgaacttca acgccgtcat cacggcccac ttcaatgcgg
    22681 tataactgca tatcgccaac gtcacgacgt tcacgacgcg gacgttcttc acgatcgcca
    22741 cgcgggccac ggtcattacg atcgcgcgga ccacggtcgt cacggtcacg gaattcacgc
    22801 ttaggacgca tcggcgcatc cggcggcaga atcagcggac gctcgccctg cgccattttc
    22861 agcagtgcgg cggccagcgt ttcgagatcc agctcttcac cttcggcaga cggctggatt
    22921 ttcgccagca gcgcacggta ctgatccaga tcgctgcttt ccagttgctg ctgaactttc
    22981 gcggcgaatt tttccagacg gcgtttaccc agcagttctg cgttcggcag ttccacttct
    23041 ggaatggtca gcttcatggt gcgttcgatg ttgcgcagca gacgacgctc gcggttctca
    23101 acgaacagca gcgcgcgacc ggcgcgaccc gcacgaccgg tacgaccgat acggtgaacg
    23161 taggactcgg agtccatcgg aatatcgtag ttcaccacca ggctgatacg ttcaacgtcc
    23221 agaccacgtg ccgcaacatc ggtggcgatc aggatgtcca gacgaccatc tttcaggcgt
    23281 tccagagtct gctcacgcag cgcctggttc atatcgccat tcaacgcggc gctgttgtag
    23341 ccgttacgtt ccagcgcttc tgctacttcc agggtcgcgt ttttggtacg tacgaagata
    23401 atcgccgcat caaagtcttc cgcttccagg aaacgcacca gtgcttcgtt tttacgcata
    23461 ccccagacag tccagtagct ctggctgatg tcaggacggg tagtcacgct ggactgaatg
    23521 cgcacttcct gcggctcttt cataaagcgg cgggtaatgc gacgaatcgc ttccggcatg
    23581 gtggcggaga acagagcggt ttgatgacct tccgggatct gcgccataat agtttcaacg
    23641 tcttcgatga agcccatacg cagcatttcg tcggcttcat ccagcaccag accactcagt
    23701 ttagagaggt cgagggtgcc gcgttttaag tgatcaagca gacgtcccgg cgtaccgaca
    23761 acgatctgcg gcccctgacg cagggcgcgt aactgcacgt cataacgctg accgccgtac
    23821 agggcaacca cgtttacgcc gcgcatgtgt ttagagaaat ccgtcatggc ttcggcaacc
    23881 tgtaccgcca gttcgcgggt tggcgccagc accagaatct gaggtgcctt cagctcagga
    23941 tcaagattgt tgagcagcgg taaagagaac gctgcggttt tgccgctacc ggtctgggcc
    24001 atgcccagca cgtcgcgacc gcccagcaga tgcggaatgc actctgcctg gattggagat
    24061 ggtttttcgt aacccagatc ggtaagggct tcaaggatag gagccttcag ccccagatct
    24121 gcaaaagtgg tttcgaattc agccatgtag tacgtgtgcc tcaaaattaa tggcggccag
    24181 tctacataac tcatcatgaa attgatctgc aattttcatt gaaaagtgtg aaccggctca
    24241 aagtaggtgt attaacgaac aacaacgccc tcacccgcga aggtgatggc aatcaaaaag
    24301 attacgggct gatatgttcg tcagctattg ctggtccgat tctgccaggt catcttggtc
    24361 ctggcccagg agcgataatt ccaacaatgc gtatcggtgc tcaacaaagt tatgaacgtt
    24421 gttggccacc gccagtttga acagagccgt ggcgctgtcc aaatccccca gacttaggta
    24481 atacttacct aaatagaagt tggtttcact gagatgctca gcgagcgagg tgttatccgt
    24541 tgcgtccgcc ttgagccttt ccatcagcgt tgcttcgcta atgtcgccca ggtagaactc
    24601 gacaatgttc catccccatt gctctttatc cgatttttcg aagcgtgctt ttaacgcttc
    24661 tttcgcctgc ttctcattaa gcttctgctc aacaagatac agccacaggc tgcggtaagg
    24721 atcattggga tcgtcttgat aaaacgccag cagatcatct tgcgctaact tatcacggcc
    24781 gccgtaatac aatgcgatac cgcggtttaa gtgcgcgtag ttgtaagttg gatcaagctc
    24841 tagtacagaa tcaaacgctt cataggcagc atcaaaattg cctgcctgcg ttaaataaat
    24901 gcctaagtaa ttgaatactt caggcatatc cggtctgatt gccagcgctt gtgaaaaatc
    24961 atttcgcgct aatgccctca aaccaagact atcatacaac actccgcgct catataaaag
    25021 ctgtgcgcgt tcgtcatcgg ttaaagcccg actggcaaga atctgttcca tacgcgccag
    25081 aatcacttcc tgctgtaaag tcggttgcaa tggtactgcg aggacttcac ttttacgcca
    25141 ggcggaatta ctgcatcctg caagcgtaag tgctgtcgca acgaaacacc agcgcaaaaa
    25201 aggcttcatt tcccactccc gaagacaacg attgaatgaa cgtcctgttc cccggtggct
    25261 caacaaggcg tccagccagg tctaaagccc cccgcactgc ggagggcaaa aggctacctt
    25321 actcggcctg ttcgctcgcc ggagcttccg gcgcagccgc aggttgagac tgctcggttg
    25381 cttctttaat gctcagacgt acacggccct ggcggtcaac ttccagaacc ttaaccggga
    25441 cttcctgacc catctgcaga taatcggtca ctttctctac acgcttatcc gcgatttgag
    25501 agatgtgaac cagaccttct ttaccgccgc cgatggcaac aaacgcgcca aagtcaacga
    25561 tacgggtcac tttactattg tagatacggc cgacttcgat ctctgcggtg atctcttcga
    25621 tacgacggat agcgtatttc gctttttcac cgtcggtcgc cgcgatcttc acagtaccgt
    25681 catcttcaat ttcgatggtg gtgccggtct cttcagtcag cgcgcggatc acagaaccgc
    25741 ctttaccgat cacgtctttg atcttgtccg tgctgatctt gatggtatgg atacgcggcg
    25801 caaattcaga gatatcgccg cgcggcgcgt tgatcgcctg ttccatcacg cccaggatgt
    25861 gcagacgcgc acctttagcc tggttcaacg caacctgcat gatctctttg gtgatacctt
    25921 caattttgat atccatctgc agcgcagaga taccgtcgcg ggaacccgcc actttgaagt
    25981 ccatatcgcc caggtgatct tcgtcgccca gaatgtcaga cagtacaacg tagttgtcgc
    26041 cttctttcac cagacccata gcgatacctg ctacggcggc tttaattggc acgccagcgt
    26101 ccatcagcgc cagagaagcg ccgcacacgg aagccataga agaagaaccg ttggattcgg
    26161 tgatttcaga caccacgcga acggtgtacg ggaatttatc catgtccggc atcactgcca
    26221 gcacgccgcg cttcgccaga cgaccgtgac caatttcacg acgcttcgga gaaccgacca
    26281 tgccggtttc gcctacggag tacggaggga agttgtagtg gaacaggaag ctgtcagtgc
    26341 gctcgcccat cagttcatca agcacctgcg cgtcacgggc agtacccaga gtcgcggtaa
    26401 ccagcgcctg cgtttcacca cgggtaaaca gagcggaacc gtgagttcgc ggcagtacgc
    26461 cagtgcgcac gtccagacca cggatcatgt ctttttcacg gccatcaata cgcggctcgc
    26521 ctgccagtac gcggctacgt accacgtttt tctcgatggc gtgcaggatt tcacccagct
    26581 cgttagcatc cagagtttca tcttctgcaa taagctgctc gatggtttcg gatttgatta
    26641 cgtcaacctg agcatagcgc tcttgtttat cggtgatgcg gtacgcgtcg ctcagacgag
    26701 attcagccag cgcagcaaca cgcgcgttca acgcgtcgtt gacggcttcc ggctgccagt
    26761 cccaacgcgg tttaccggct tctttcacca gatcgttgat cgcctggata acaacctgct
    26821 gctgctcgtg accgaatacc accgcgccca gcatagtgtc ttcgctcagc agttcagctt
    26881 cggattccac catcagcaca gccgcttcgg taccggcaac caccaggtcc agcttgcttt
    26941 ctttcagctc gtcctgggtc gggttcagta cgtactggtc attgatgtaa cctacgcgcg
    27001 ccgcgccgat tgggccgttg aacggaatgc cggacagcga cagcgcagcg gatgcgccga
    27061 tcatcgccac gatatccggg ttaacctgcg ggttaacgga aacgacggtc gcaataacct
    27121 gcacttcgtt aacgaaacct tccgggaaca gcggacgaac cgggcggtca atcagacgcg
    27181 cgatcagggt ttcgccttcg cttggacggc cttcacgacg gaagaagctg cccgggatac
    27241 gaccagcagc gtaggtacgc tcctgatagt taacggtcag tgggaagaag tcctggcctg
    27301 gcttggcttt tttctggccg acaacggtaa cgaatacggc ggtgtcatcc atgcttacca
    27361 taacagcggc agtggcctga cgcgccatca tgccagtttc cagcgtaacg gtatgctggc
    27421 cgtactggaa ttcacgaacg atcggattaa gcaaaataat atcctttcca atttttgacg
    27481 gcacaatacg cgccgtcgtt aatacccgat cttctgcgca tcctcgcgac taatgacaac
    27541 cctaaccctg atatgggtaa agcctctcat tagccgcgcg aacctctgca acggaagatc
    27601 attcatagca acaatacatt agtttccagc gaattgctgc catctgctgg aaaaaagggg
    27661 ccatgaaggc cccctctttc tgaaactcga aagaattagc gacgcagacc cagacgctca
    27721 atcagcgcgg tgtagcgtgc aacatcttta cgtttcaggt agtcgagcag tttacgacgc
    27781 tgagaaacca tacgcagcag accacgacgg ctgtggtgat cttttttatg ctctgcaaag
    27841 tgaccctgca ggtggttaat ctgtgcagtc aacagagcaa cctgaacatc ggtagaaccg
    27901 gtgtcgtttg cgtcacgacc gaactcagaa acgattttag ctgtagcttc agtacttaga
    27961 gacattttaa aactccaaag tatttaagaa tgagaggacg ccgatctcta attcagcgat
    28021 cccagtgtac gccgcgtaaa ctgttaaata atttacgcga cgttaagcgg cggtattcta
    28081 ctcgcagcgc tctcttatcg caagacgaag cgacattacg ccgggtactc tactaccagc
    28141 cgacgaggcg cgacacggcc ttcgtcgtca atttcgccca taccgataaa tttatcgtct
    28201 tcaccttccg tcacacgaac cagtcccttc aacggcgcgc ccgtggtacg aaccgggttg
    28261 ccatttttga agtataccga agatgttaac ggcagattaa caacaggata gtccgaagcc
    28321 ggactatcca ttggcatcaa taatggatcg agcaactgcg ccgccggaac gccctgctgt
    28381 tccgcctgtg ctaccagcgt ctgcaagtgc tccagcgtca ccatacgatc caccggatac
    28441 ttgctgaccg tcagacgacg caggtacgtt acgtgcgcgc cacagcccag tttctcacct
    28501 aaatcatcaa taatagtgcg aatataggtg cctttggagc aatgaacttc cagctccagc
    28561 tcgttacctt catggcgaat aaacagcagc tcatagacgg taatcgggcg ggcttcgcgc
    28621 ggcacttcga taccctggcg ggcatattcg tacagcttcc tgccctgata cttcagcgcc
    28681 gaatacatcg agggaatctg ttcgatatcc ccacgaaagg tctccagcgc gctcgcaagc
    28741 tgctcagcgc tgaaagtcac cggacgctcc tgcacgattt gaccatcggc gtcagaggta
    28801 tctgtgcgct gccccagacg ggcaataaca cgatagcgtt tgtcagaatc cagcaagtac
    28861 tgcgaaaatt ttgtcgcttc gccgaggcaa atcggcaaca tgccggtcgc cagcgggtcc
    28921 agcgcgccgg tatgcccggc gcggttggca ttgtagatgc gcttaacttt ctgcagcacg
    28981 tcattgctgg acataccctg cggcttatcc agcaacagaa cgccgtgaat gtcgcggcca
    29041 cgacgacgag gacgactcat cagtcctcct tgctgtcgtc cgggttcaca cgacgttctt
    29101 cgtcatgttt caccacgtta gtcaccaggt tggacatacg catcccttcc accagcgagt
    29161 tatcgtagaa gaaggttagt tccggcacga tgcgcagacg catcgcttta cccagcaagc
    29221 tgcggatgaa accagacgct tcctgcaggg ccttaatgcc gtttttcaca gccgcttcgt
    29281 cctgatcgtt gaggaacgtc acgaatactt tggcgtatgc cagatcgcgg gacatttcaa
    29341 cacccgatac ggtggtcatc atacctacac gtggatcttt gatttcgcgt tgcaggatga
    29401 gcgcgatctc tttctgcatc tcttgcgcta cgcgctgcgg gcgaccaaat tctttcgcca
    29461 taataaattc tccagaataa agacaaaaaa ggggccataa gccccttttt aaatttcttg
    29521 ccgggtggcg cttcgcttac ccggcctacg cctaatcatc ttctaaggat tttggattgc
    29581 aacaaggcgg caagctcgta aatccccggg agcatagata actatgtgac cggggtgagc
    29641 gagcgcagcc aacgccgttg cggcccaaaa gacgacgaag attaagcgat ggtacgttgg
    29701 atctcgataa tctcgaacac ttcaatcata tcgccaacgc gaacgtcgtt gtagttcttc
    29761 acgccgatac cacattccat gccgttacgg acttcgttaa cgtcatcttt gaagcggcgc
    29821 agggattcca gctcgccttc atagataacc acgttgtcgc gcagtacgcg gattggatta
    29881 tggcgtttaa ttgtaccttc ggtaaccata cagcccgcga tcgcgccgaa tttcggcgat
    29941 ttgaacacat cgcgcacttc agccagaccg atgatctgct gtttcagttc cggagacagc
    30001 atgccgctca tcgccgcttt cacttcgtcg atcaagttat agatgacgga gtagtaacgc
    30061 agatccagac tttcggattc aatcacttta cgcgcagaag catcagcacg aacgttgaag
    30121 cccaccagaa tcgcgttgga cgccgcagcc agggtcgcgt cggtttcggt gataccacct
    30181 acgccagaac cgatgatctt cactttcact tcgtcggtag acagtttcag caaggagtcg
    30241 gagatcgctt ccacggaacc ctgtacgtca gccttcagca cgatgttcac ttcgtgaact
    30301 tcgccttcgg tcatgttgac gaacatgttc tcgagtttag atttctgctg acgagccagt
    30361 ttaacttcac ggaatttacc ctgacgatac agagcaactt cacgcgcttt cttctcgtcg
    30421 cgaaccacgg tcacttcgtc accggcagcc ggaacgccgg acaggccgag gatttccacc
    30481 ggaatggacg gacccgcttc cagcacttcc tgacccagtt cgttacgcat cgcacgcacg
    30541 cggccgtatt cgaagccaca cagcacgata tcgcccttat gcagcgtacc ttcgcgtacc
    30601 agaacggtag ccaccggacc acgaccttta tccaggaagg attcgatcac cgcgccgctc
    30661 gccatacctt tacgaaccgc tttcagttcc agaacttcgg cctgcagcag gatagcgtca
    30721 agcagttcgt cgataccggt gcccgctttc gcagacacgt gaacgaactg gctctcgccg
    30781 ccccactctt ccggcagaat gccgtactgg gacagttcgt tcttcacacg atccggatcc
    30841 gcttccggct tatcgatttt gttcaccgca accacgaccg gcacacctgc cgctttcgcg
    30901 tgctggatag cttcgatagt ctgcggcatc acgccgtcgt ctgctgcaac aaccagaacc
    30961 acgatatccg ttgcctgagc accacgagca cgcatggagg taaacgcggc gtggcccggg
    31021 gtgtccagga aggtgatcat cccgttgtca gtttcaacgt ggtaagcacc gatgtgctgg
    31081 gtaatgccac ccgcttcgcc agaggccact ttcgtggaac gaatgtagtc cagcagagag
    31141 gttttaccgt ggtcaacgtg gcccatgatg gtcacaaccg gtgcgcgcgg ttcagccgca
    31201 gcgccggtat cacggtcgct cattaccgct tcttccagtt cgttttcacg acgcaggata
    31261 actttgtggc ccatctcttc ggcaaccagc tgtgcggttt cctggtcgat gacctggttg
    31321 atggtggcca tggcgcccag cttcatcatc gctttgatga cctgagaacc tttcaccgcc
    31381 atcttgttcg ccagttcgcc gacggtgatg gtttcaccga tcaccacgtc acggttaacg
    31441 gcctgagcgg gcttctggaa gccttgctgt aaagaagacc ctttacgctt gccgccttta
    31501 ccgccgcgaa ccgcagcacg cgcttcttcg cgatcggctt tggattcggc atgtttgcct
    31561 tttttcgccg gacgcgccgc ttttgcatta cggccacgac cacgaccacc ttctacttca
    31621 cgatcgtttt cgtcttcggc ctggcgcgcg tgctgagaag tggtgacatg atagtcactg
    31681 gtgtcttcta ctggctcagg cgttgcggtc catttgtttt cttccgccat gcggcgagct
    31741 tcttctgcta cacgacgcgc ttcttcttcg agtttgcgac gtgcttcttc ttccgcttta
    31801 cgcttcagct ctgcagcttc attctcacgg cgggcttttt cggcctgggc ggttttggtc
    31861 atatcgtcag tctgttgatt gctcactttg tctttttccg cagcttcacg tttcgctttt
    31921 tcagcggctt cacgcttagc ttgttctgcg gcctcgcgtt cagctttttg ttgcgcctcg
    31981 cgtttggcct gttcttctgc ctcacgacgg gcttgctctt ccgcttcacg ctgcgcctgc
    32041 tcttccgcgg ccaggcgttc agcctcttgc ggatcgcgtt tcacaaaggt gcgcttcttg
    32101 cggacttcga tttgtaccga tttacttttt ccaccggtac caggaatatt cagggtgctg
    32161 cgcgttttac gctgcagcgt caatttatcg gggccagaaa ccgcttcgcg gttcaggtgc
    32221 gccagtaaag tctgtttttc ttgtgcggac acagagtcgt cagcagattt ccggatacct
    32281 gcatcagcaa actgctgtac caggcgatcc acggaaacct gtctctctgc ggccagcgct
    32341 tttagggtta aatctgtcat gctgttcctt cctgctacag tttattacgc ttcgtcgccg
    32401 aaccagcaaa tattacgggc agccataatc agctcaccgg ctttttcgtc ggtcaaccct
    32461 tcgatatcag ccagatcatc aatgccctgg tcggcgagat cttccagcgt acaaacacca
    32521 cgagccgcca gtttgaaagc catatcgcga tctaatcctt ccagattcag cagatcgtca
    32581 gccggtttgt tatcacctag gcttgcttcc tggtcctgcg ccagagtggc cagtgcgttt
    32641 ttagcacgct cgcgcagtgc ttcaacggtc ggctcatcaa ggccgtcaat ttccagcagt
    32701 tctttcattg gcacataggc cagttcttcg agcgtggaga aaccttcttc taccagaacg
    32761 gtcgcgaact cttcatcaat atcaagatat ttagtaaaga tctcgatagc ggcatgtgct
    32821 tcagcctgat gtttagcctg caagtcatca acggtcatta cgttgagttc ccagccgctc
    32881 aattgcgaag ccaagtggac gttctgacca ttacgtccga tcgcctgcgc cagattaccg
    32941 gcttcaacgg cgatatccat ggtatgttta tcttcgtcca ccacgataga cgcgacatct
    33001 gccggcgcca tcgcattaat gacgaactgc gccgggttat catcccacag cacgatatcg
    33061 atacgctcac cgcccagttc ggtagagacc gcctgaacgc gcgcgccgcg catccccacg
    33121 caagcgccga ccggatcgat acgcttatcg ttggttttca ctgcgatttt cgcacgagaa
    33181 cccggatcgc gagccgccgc tttaatttca atcacttctt cgccgatttc cggcacttcg
    33241 atgcggaaca gctcgatcag catttccggc ttggaacggg tgacgaacag ctgcgcgcca
    33301 cgcgcttccg ggcgaacagc atacagcacg ccgcgaatac ggtcgccagg gcggaagttt
    33361 tcgcgcggca gcatatcttc acgcagaatc accgcttcag cgttaccggc catcccttcg
    33421 gatttaattt ccaaagagat attgtcgcgg ttcactttct tcaccacgcc agtgacgatt
    33481 tcgccttcct ggtcgcggaa ctgatcgaca accatcgcgc gttcagcttc acggactttc
    33541 tgcacgataa cctgtttcgc agtctgcgtg gtgatacggt caaaggtgac agattcaatc
    33601 tgatcttcaa catagtcgcc gacattcagg ctttcgtctt caaagcgcgc cgcttccagc
    33661 gtaatttcct tcgtcggcat ggtcacttct tcaacgatca accaacggcg gaaagtatca
    33721 aaatcaccgc ttttacgatc gatttctaca cgaacatcga tctcctgctc atattttttc
    33781 tttgttgctg tcgccagcgc actttccagc gcttcaaaaa ttttttcgcg tggcagcgct
    33841 ttttcgttgg agacggcttc aacaacagcc aaaatttctt tgttcatcgc gggcttttca
    33901 cctcatccag actgttaaaa gtggggaacc aggttcgcct tctggatatt actcagcgcg
    33961 aacacttcat ctttgccttc gactgtgacg gtaatcattt caccgtccac cgctttgata
    34021 atgccctgcc acttgcgacg gttctgtacc gccatgcgaa gaaccagcgc gacctcttca
    34081 ccctggaaac gcgcataatg atcggcagtg aacataggac ggtcgagacc cggtgacgag
    34141 acttcaaggt tgtaagccac ggagatagga tcttcaacgt ccagcaccgc gcttacctgg
    34201 tggctcacat cagcacaatc atcaacattg atgccatctt cactatcaat atagatgcgc
    34261 agtgtggatg tgcgaccgcg aataaattcg atgccgacca gctcgtagcc taaggcttca
    34321 actggcgctg taatcatctc tgttaatttt tgctctaatg tggacaagcc cacccccaag
    34381 acataaaaaa agggcctaaa gcccagttat tctgtagtca gataacaaaa aaccccgata
    34441 aatcggggct ttagataact gaaccctata accgcaacgg cggtctggtg taccttccga
    34501 aagaattttt ttcaaatcca gctacgaagg acataatctt cacagtatat ttgaaaaaga
    34561 actctaaggg aaagtggttg cgggggccgg atttgaaccg acgaccttcg ggttatgagc
    34621 ccgacgagct accaggctgc tccaccccgc gcctgaaacg tggcaaattc tactcgtttt
    34681 gggcaaaatt tgcaaatact gctgggattt ggtaccgagg acgggacgta aaatctgcgc
    34741 acagtatagt gaccaggcat gagttatgtc aaccctattc ccaatatgca gatgaatgaa
    34801 tatcactctt cgttatactc atcccacctc tcctgcttat acacgcattt cacaacgtta
    34861 tttcagtaaa ccttcactaa atgcttcctg tctctgctaa aagatgatta aatgaaaact
    34921 catttatttt gcataaaaat gcactaaagc agaaaccgat ctcattatca gtcaatcaag
    34981 cagggttcta ttctatgacg acgattctta agcatcttcc agcaggtcaa cgtattggta
    35041 tcgctttttc cggcggtctg gacactagcg ccgcgctgct gtggatgcga caaaaaggag
    35101 ctgtcccata tgcctatact gcgaatctgg gacaaccgga tgaggatgac tatgacgcca
    35161 ttcctcgtcg cgcaatggag tatggcgcag agaatgcccg cctgattgat tgccgcaagc
    35221 agttggttgc agaagggatc gcagcgattc agtgcggcgc tttccataat acgactggcg
    35281 gactgaccta tttcaatacc acgccgctgg gccgtgccgt gaccggcacg atgctggtcg
    35341 ccgcaatgaa agaagacggc gtgaatatct ggggcgacgg cagcacctat aaaggcaacg
    35401 atattgaacg tttctatcgt tacggcctgc tgaccaacgc cgagctgcag atttacaaac
    35461 cgtggctgga taccgacttt atcgatgagc tgggcggccg tcatgagatg tctgaattta
    35521 tgattgcctg cggtttcgac tataagatgt cagtcgaaaa agcctactcc accgactcca
    35581 acatgctcgg cgcgacgcac gaagcgaaag atctggagtt tcttaactcc agcgtcaaga
    35641 tcgtcaaccc gattatgggc gtgaagttct gggacgaaag cgtgaagatc ccggcagaag
    35701 aggtgaccgt ccgtttcgaa cagggacatc cagtggcgct gaacggtaaa accttcagcg
    35761 atgatgttga gatgatgctg gaagcgaacc gcatcggcgg acgtcacggc ctgggcatga
    35821 gcgaccagat cgaaaaccgt atcattgaag cgaaaagccg cggtatttat gaagcccccg
    35881 gaatggcact gctgcacatc gcttacgagc gtctgttgac cggtattcac aacgaagaca
    35941 ccattgaaca gtatcattct catggtcgtc agttgggtaa actgctgtat cagggtcgct
    36001 ggttcgactc tcaggcgctg atgctgcgtg acggcctgca acgttgggtc gccagccaga
    36061 ttaccggtga agtgacgttg gagctgcgtc gcggcaacga ctactccatc ctgaacaccg
    36121 tgtcagacaa cctgacctat aaggctgagc gtctgaccat ggagaaaggc gagtccgtgt
    36181 tctcgccaga cgatcgtatc ggtcagttga ccatgcgtaa tctggacatt actgataccc
    36241 gcgagaaact gttcggctac gcgaaagcgg gtctgttaac cgcctcttcc gcgaccggtc
    36301 tgccgcaggt tgagaatctg gaaaacaaag cgaagtaaac atttatcatt ctaaggccgc
    36361 gaaagcggcc ttttttatgc gcggaatata aggtgtctat aggcctgata aacgtagcgt
    36421 catcaggcgt tgtaataatg tcggatggcg gcgtaaacgc cttatccgac ctacagaaaa
    36481 tcacaaataa cagacgaaaa aaaagacgct tttcagcgtc tttctttcgg aatattggta
    36541 ccgaggacgg gacttgaacc cgtaagccct attaggcact accacctcaa ggtagcgtgt
    36601 ctaccaattc caccacctcg gcacggatac tgctattagc gcgggatatc gctggtcggc
    36661 tgggccggtg cagcaggttg agtctgctcg gttttcgccg gcgcgctcag attttcccac
    36721 tcgcttcctt tattggtttt gttgctattg atattaccca acaccagact gatgatgaag
    36781 aacagcgtcg ccaataccgc cgtcattcga gtcatgaagt taccagaacc acttgaacca
    36841 aatagcgtag cggaagcgcc tgctccgaag gaggctccca tatcagcgcc tttaccttgc
    36901 tgcagcatga tcagacctac aaggccaatt gccacaataa ggaaaacaac taaaagagct
    36961 tcgtacataa tcaacctgtt ccttgcggag ttgccgcgta ccaatgcttc taccaataaa
    37021 gcgggatttt tactgtttcc cactgaagcg ggtgtgaata ctaaccaaag cgaatgacct
    37081 tcgcaagggc aatttaagcg cattgtatca actgcggaaa aaaacagcaa aagcgttgtt
    37141 ttttgcgggc agtaaggcgg caaccgccgc ctttttagtc acttaaacgc ttaaacggct
    37201 tttaccgcat ccgcgatacg atgggcgaaa gccgtaacct gcgcttcatc ctcgccttca
    37261 accatcacgc gaatcagcgg ttcggtaccg gatttacgta gcagtacccg cccacgattg
    37321 ccgagcgtgg cttctacgtc cgccgttacc gctttcaccg cttcattttc cagcggatcg
    37381 ccgctaccag cggtgtaacg cacgttaacc agaatctgcg ggaacatttt cattccgctg
    37441 cacagatcgt gcagactcat atgattacgc accatcgccg ccagaacttg tagccccgcc
    37501 acaataccgt cgccagtggt cgttttatcc agcagaataa cgtgaccaga gttttccgcg
    37561 ccgatgcgcc agcctttttc ctgcaatttt tccagcacat agcggtcgcc cactttcgcc
    37621 cgggcaaacg gaatgccaag ctgcttgagc gccagctcca gccccatatt gctcatcagc
    37681 gtccccaccg cgccgccgcg cagttgcccc tggcgcagcc cttcgcgcgc gatgatatac
    37741 atgatctgat cgccatcgac tttattgcct tcatggtcaa ccatgatgac ccggtcgccg
    37801 tcgccgtcaa gcgcgatgcc gaggtccgcc ttctccgcca acacgcgcgc ctgcaacgcg
    37861 cgcacgtcgg tcgcgcccac ttcttcatta atgttgacgc cgtttggctc acagccgatg
    37921 gcgatcacgg tcgcgcccag ctcgcgcagc acattcggag cgatgtggta ggtagcgccg
    37981 ttggcgcaat ccacaaccac tttcaggccg ttgaggctca gttcgttcgg gaaggtgcct
    38041 ttacagaact caatatagcg tccggcggcg tcgacgatgc ggctggcttt ccccagctcg
    38101 gcggagtcta cgcaggtgat ctctttttcc atttcggctt cgatggcttc ttccacatcg
    38161 tcaggcagtt tcgtaccgtc gatagagaag aatttaatgc cgttatcata gaacgggtta
    38221 tgggaagccg agataacgat acccgcctcc gcgcggaaag tccgcgtcag ataggcgacg
    38281 gctggcgttg gcataggtcc ggtaaacgag gccgacagcc ccgcagcggc aaggcctgcc
    38341 tccagcgcgg attccagcat atagccggaa atacgcgtat ctttaccgat aatgatttta
    38401 cgcgaaccat gacgcgccag cacttttccg gcagcccaac ccagtttaag cacgaaatca
    38461 ggtgtaatgg gggcattgcc tacacgtccg cgaatcccat cggtaccgaa atatttacga
    38521 ttactcatag cgtttgtttc cctttgcaga cagagtggct tccaccaccc gcatcgcctc
    38581 tacggtttct ttgacgtcat ggacgcgaat gatctgcgcg ccctgcatcg cagcaattac
    38641 cgcgcacgca aggctaccgt tcagacggtc tgatggtccc acgttaagta actgaccaac
    38701 catcgtttta cgtgacatgc ccaccagcag cggcaggtta aaatgatgaa actcacccag
    38761 tcgcgccagt aaggtataat tgtgagagag atttttaccg aaaccgaatc ctgggtcgag
    38821 caacaatttc tcttttgcga tgccggcctt ctcacaacgt gctatttgct caataaagta
    38881 gcgattcacc tcggcaaaga catcgtcata tttcggcgcc tcctgcatgg ttttggggtt
    38941 gccctgcatg tgcataagac tgaccggcaa gccggtttcc gctgccgctt ccaacgcgcc
    39001 gggttcggag agtgaacgga catcattgat aatatgcgcg cccgcccttg ccgcttcacg
    39061 gatcacctcg ggtttagagg tatccacaga aatccacact tcaaaacgtt gcgcgattgc
    39121 ttccagtacc ggaataacgc gatccagctc ttcttccacg ctcacttctg ccgcgcctgg
    39181 tcgcgttgat tcccccccca catcaataat tgtcgccccg gtattcacca ttaaattcgc
    39241 atgtttcacc gcctcaatca gcgtgttatg cgcgccgccg tcggagaacg aatccggcgt
    39301 tacgttcagg atccccataa catgcggatg agtgagatcg agcgtggcgc cctgagcgaa
    39361 gagtttcatg gtcaaaatcc ctgttttatt tatggtgagt taaaaaaaga aaaaccccgg
    39421 ggcaagcccc agggtttcgg tgagcgctaa acataatgtt gtaaaacaaa tgcttatttg
    39481 tcgcccagct gctctgacat cgtgttgccc gggttcggcg tgcgtggttc atcaaccgga
    39541 cgcggcgcct gaggcgtacc attgctgtca gagttattgg tgccgtttgg atcttcccag
    39601 cccgcaggcg gacgcacttc acgacgcgcc atcaggtcat caatctgcgg cgcatcgatg
    39661 gtttcatatt tcatcagcgc atctttcatc gcgtgcagaa tatccatatt gtcagtcagg
    39721 atctgacgag cgcgattgta gttacgttca atcagcgctt tcacttcctg gtcgatgata
    39781 cgcgcagttt catcagacat atgtttcgct tttgcgacgc tacggccgag gaacacttcg
    39841 ccctcttctt ccgcgtacag caacggaccg agtttctccg agaagcccca ctgggtgacc
    39901 atgttacgcg ccaggttagt cgcgacttta atgtcgttcg acgcgccggt agaaacatgc
    39961 tcaacgccgt agataatctc ttccgccaga cggccgccgt acagcgtgct gatttggctt
    40021 tccagcttct gacggctggc gctgatcgcg tcgccttcag gcaagaagaa ggtcacgccc
    40081 agcgcacgac cacgcgggat aatcgtcact ttgtgcaccg gatcgtgttc cggcaccagg
    40141 cgaccgataa tcgcgtggcc cgcttcgtgg tacgcggtcg actctttctg cgcttccgtc
    40201 atcaccatgg agcgacgttc ggcgcccatc atgattttgt ctttcgcttt ctcgaactca
    40261 accatcgaca ctacgcgctt gttgccgcgt gcggcaaaca gcgccgcttc gttgaccagg
    40321 ttcgccaggt ccgcaccgga gaagcccggc gtaccgcgcg caatgatcgc cgcatcaatg
    40381 tccgtcgcta acggtacgcg acgcatatgc accttcagaa tctgctcacg accgcgaaca
    40441 tccggcaggc ctaccaccac ctgacggtca aaacggccag gacgcagcag cgccgggtca
    40501 aggacgtccg gacggttagt tgcggcgata acgatgatac cttcgttacc ttcgaagccg
    40561 tccatctcaa ccagcatctg gttcaacgtc tgctcacgtt catcgtgacc accgcccaga
    40621 ccagcgccac gctggcgacc tacggcgtcg atttcatcga tgaagataat gcacggtgcc
    40681 gctttcttgg cttgttcgaa catgtcacgc acacgagatg cgccgacacc cacgaacatt
    40741 tccacaaagt cagaaccgga aatcgtaaag aatggcacct tcgcttcacc cgcaatggct
    40801 tttgccagca gggttttacc ggtacccggc gggccgacca tcaggacgcc tttcggaatt
    40861 ttaccgccca gcttctggaa acggctcggt tcacgcaggt attcaaccag ttccgccact
    40921 tcttctttcg cttcgtcaca acccgcaacg tcagcaaacg tggttttgat ctgatcttcc
    40981 gtcagcatac gcgccttgct cttaccgaac gacatggcgc ctttgccacc gccgccctgc
    41041 atctgacgca tgaagaagat ccagacgccg atcagcaaca gcatcgggaa ccaggagatg
    41101 aagatagaag ccagcaggct tggctcttca ggtggttcgc caacaacctt gacgttttta
    41161 gtcagcaggt tatcaagcag cttcggatca ttaatcggaa tgtaagtcgt gtaacggtta
    41221 ctatctttct tggtaacgtt gatctcacgt ccgttgatac gcgcttcgcg aacctggtcc
    41281 tgattgacct cttgcaggaa ggtagagtaa tccaccttac ggccattaga ctcgctgggc
    41341 ccaaagctct ggaatactga catcagcaca acggcaatga ccagccagag tattaggttt
    41401 ttcgccatgt cactcaaggg attaacctct tattacaact gtgttaaaaa cagcgtcagg
    41461 atactctata tccagtttct ttcaaacctt acgtctgaaa tctgccggtt atcactttcg
    41521 cccggtcgct acaatgtaca cttcacgcga acgcgcgcgc gaagagtccg gcttacgaac
    41581 tttaaccttc gtaaacaggg agcgaatttc ccttagatac tcatcgaaac cttcgccctg
    41641 gaacaccttc actacaaaac ttccgcctgg cgccagcaca tcgcggcaca tatctaacgc
    41701 cagctccacc agatacatgg cgcgggggat atccaccgcc ggtgttccgc tcatgtttgg
    41761 tgccatatcc gacatgacaa cttgtacttt actgtcaccc acgcgttcca gtaacgcttt
    41821 catgacaagt tcatcacgaa aatcgccctg aagaaagtcc acaccaacga taggatccat
    41881 aggtaaaaga tcacaagcga tgatgcggcc tttgccgcca atctgcgtga ccacatactg
    41941 tgaccaccct cctggcgcag cgccgagatc gactaccgtc attcccggct taaaaagttt
    42001 gtcactttgc tgtatttcat caagtttaaa ccaggcacgg gagcgtagcc cctttttctg
    42061 cgcctgttga acatatttat cgctaaagtg ttcctgaagc cagcggcttg agctggcaga
    42121 acgcttttta cctgtcattt aactttcccg tcggggcagt tcatcgtagc caatggcgta
    42181 aatttctaca cgcctatttg gcgatataag ggagatggcg gtagaatgac ccgttttcaa
    42241 tcccaacgta agcaaaaata tacgatgaat ctgagtacta aacaaaaaca gcacctaaaa
    42301 ggtctggcac atccgctcaa gcctgttgtt atgcttggca ataatggttt gaccgaaggg
    42361 gtactggccg agattgaaca agcgttagag caccatgaac ttatcaaggt gaaaatcgcc
    42421 tcggaagatc gcgaaacaaa aaccttgatc gtggacgcta tcgtgcgcga aaccggcgcc
    42481 tgtaacgtac aggtcatcgg taaaacgctg gtgctgtatc gcccaactaa agagcgtaaa
    42541 atctcgctgc cgcgttaagg atatcctaaa gtcgaacaca aaatctgtgt aaaacgaggg
    42601 gttttccacg agcaggagag caaaatgcca cgctctctcc gttgataaaa ggccgctatg
    42661 cggccttttt cctttcttta caatacacca acaatttgcg tattgagtac tgcttaaagg
    42721 tattccactt taagcacttc gtattccaca tcgccgccag gcgttttgat caccacgacg
    42781 tcatcctgct ctttgccaat caggccgcga gcgattggcg agtttaccga aatgagattt
    42841 tgcttaaaat ccgcctcatc atcgccaaca atacgatagg tctgctcttc gtcggtgtcc
    42901 aggttcagca ccgtgacggt agcgccgaaa atcacgcgac cattgttcgg cattttggtg
    42961 acgtcaatca cctgcgcatt cgacagtttt gcttcgatat ctttaatgcg cccttcgcag
    43021 aaaccctgct gttcgcgtgc agcatgatac tccgcgtttt cttttaaatc gccatgttcg
    43081 cgcgcttcgg cgatagcggc gatgatttca ggacggcgca cagatttcag aaaatccagc
    43141 tcttcgcgca gtttttcggc tccgcgtaag gtcatcggaa tagcttgcat ttgttatacc
    43201 tcttgaacat tcctgtaggg ggcaatgaac tctaccccgg ctgctaagcc agccccggca
    43261 tatgccatac cagggtcaga agcaaaaaaa caccaacccg ggcgcgcagt cccaggtcag
    43321 ctacaatttc ctctttgata accattttac cctggagttc cctatgggtc atcgtttact
    43381 ttttagggcg ttgcgccgta gtatgacggc ttgtttccag ggtgttagcg cgagattatg
    43441 cgattttcca gatttatcat cggattgacc accagtatag cgttcagcgt tcaggccgcg
    43501 aatattgacg aatacatcaa acagcttccg gccggcgcca acctcgcgct gatggtgcaa
    43561 aagattggcg cgcccgcgcc ggctattgat tatcatagtc agcagatggc gcttcccgcc
    43621 agtacccaaa aggtgattac cgcgctggcg gcgctgattc aactcggccc ggatttccgt
    43681 tttacgacca cgctggagac taaaggcaac gtcgataacg gcatcctgaa aggtgactta
    43741 attgcgcgat tcggtggcga tccaacgcta agacgtcagg atattcgcaa tatggtcgcg
    43801 acgctgaaaa agtcaggcgt cacgcaaatc gacggcaatg tgcttatcga cacgtcgatt
    43861 ttcgccagcc acgataaagc gccaggctgg ccgtggaacg acctgacgca gtgtttcagc
    43921 gcgcctcccg ccgccgccat tgttgaccgc aactgttttt ctgtgtcgct ttatagcgcg
    43981 caaaaaccaa acgatttagc ttttattcgc gtggcctctt attatccggt aacgatgttc
    44041 agccaggtac ggactctgcc gcgcggttcg gcagacgcgc agtattgcga gctggatgtt
    44101 gtgcctggcg atttgaaccg ttatacgctt accggctgtt taccacagcg cgccgacccg
    44161 ctgccgctgg cctttgctat tcaggacggc gccagctacg cgggcgcgat cctcaagcag
    44221 gaactgaaag aggccgggat aacttaccgc ggcacgctgc tgcgccagac gcaggttaac
    44281 gagcccggaa cgatcgtcgc cagtaaacag tcggcgccac tgcacgatct gcttaagatt
    44341 atgctgaaaa agtcagacaa catgatcgcc gatactgttt ttcggatgat tggtcatgtc
    44401 aggtttaacg tgcctggcac ctggcgggcg ggatcggatg ctgttcgcca gatcctgcgc
    44461 caacaggcgg gaattgatat cggcaatacc attattgccg acggttccgg tctttctcgc
    44521 cataacctga tcgctcccgc cacgatgatg caggtgctgc aatatatcgc ccaacacgat
    44581 aacgagctga actttatctc tatgctgccg ctggcgggct atgacggttc attgcaatac
    44641 cgcgccggcc tacatcaggc gggcgtagac ggtaaggttt cggcgaaaac cgggtcactg
    44701 cagggcgtgt acaacctggc gggctttatt accaccgcaa gcgggcagcg gatggcattt
    44761 gtacagtatt tgtccggcta cgcggttcca cctgccgatc agcgtaatcg acgtattccg
    44821 ctggtacgct tcgagagtcg attgtacaag gatatttatc agaataactg agtgcattat
    44881 tgccggatgg cggcgctaac gcgtcttatc cggcctacaa agaacataat aaaacgggcc
    44941 gcaaatgcgg cccgttggct tttgtaggcc ggataagcgt aagcgccatc cggctacgag
    45001 attaacgttt gtagatgaac tcgacgcctt cttcgtcgtc ttcatcccag tcgtcatccc
    45061 agtcatcgtc tgcgtcttct tccacttcag ccaactgctg gcgatgataa tcgtcccaca
    45121 tgaactcgac tttttccggc tgttttgctt cttcagcctg cgcgatcgga ttctcgatga
    45181 taaaggtcat cacatcccag cagagatctt tcacccctag ctgactggca gcggaaatca
    45241 gatagtattt cccttcccag cccaacgctt cggcgatcgc tttcgctttc tcttccgctt
    45301 cggatttatc catcagatcg atcttgttga acactaacca gcgcggttta gccgccagat
    45361 cctggctgta tttttccagt tcgccaataa tgatacgggc gttttccacc ggatcggaac
    45421 catcgatcgg atcgatatca atgaggtgca gcagtacgcg gcaacgttcg aggtgcttca
    45481 agaagcgaat ccccaggccc gcgccttccg ccgcgccttc gatcaacccc ggaatgtcgg
    45541 ccaccacaaa actcttttcg ctgtccatac gtaccacgcc caggctcggc accagcgtgg
    45601 taaacggata gtccgcgact ttcggttttg ctgccgatac cgcgcgaatg aacgttgatt
    45661 taccggcatt tggcatcccc agcatcccga catccgccag cagcatcagt tccagcagca
    45721 ggtcgcgctt atcgcccggc gtaccattgg ttttctggcg cggcgtacgg ttaaccgagg
    45781 atttaaaacg ggtattgcct aacccatgcc agccgccctt cgcgaccaac agacgctgac
    45841 cgtgtttggt catgtcgccc atcgtttcac cggttccttg gtcgataacg cgcgtaccga
    45901 ccggcacttt gatggtcacg tctttaccgc gtttaccggt acagtcgcgg ctcgcgccat
    45961 tctgaccacg ttcagcgcgg aacgattttt caaagcggta atcgatcagc gtattcaggt
    46021 tttcatcggc ttccatccag acgtcgccgc cgtcgccgcc atcaccgccg tccgggccgc
    46081 ctttcgggat atatttttcg cggcggaagc tcacacagcc attaccgcca tcgcctgcaa
    46141 cgaccagaat cgatgcttca tcaacaaact tcattttatt ctccgtaaat cattcgcctg
    46201 agcggggttg cgaaaccacc gtttcatgct tgcgtaaacc gccccaaata cgatgaccaa
    46261 tggcggaata catcgcgccc gcaaccacga caaacgcacc gagataacct aaaaggttta
    46321 acatcggtct ggcgaagaaa tcgggccagg ccatagataa aagatctgaa aacagcaggg
    46381 taaatagcgg tgtaagcgtg attatcgcgc tcacctgcgc cgcctgccaa cgcgccatcg
    46441 cttccgccag ggcgccatat cctaccagcg tatttagccc gcagaaaatc aaacaggcga
    46501 gctgccagtc gctcagttgc gctatcacca tcggttttgc caacggcaaa agcgctatcg
    46561 tacataaagt gtacagtaaa aacaggatct gctgcgaggc cagacgtcgc aataatactt
    46621 tttgcgccac gccatagctc acccacacca tcgccgcgcc tacgccaaaa ataacgcccc
    46681 aggtgtagtc ggtcagtcgg gtaaaaatct cgatcagact ggtgttaaaa aacattacca
    46741 gcccgctcaa taacatcagc gcgccaatca cctgcgtacc gcgcatcttt tctttcagaa
    46801 taaagacgct ggcgaccatc atgccaaccg gcgagagctg gccgataacc tgcgacgcgg
    46861 ttgggcttaa atattgcagg gaagaactga acaaaatgaa attaccgaac agtccgcagg
    46921 tcgctatcgc caataacacc aaccagcgcg gcttacgaaa aatacgcagc ggcggcagct
    46981 ttctttttac tgccagtatc gccccgaggc caatactggc cattaagaag cggtagaaga
    47041 caatggttga aggctccatc acctccagca cttgcttcat tgctattggc aacgctcccc
    47101 agcacatcgc ggtagtgagc gctaaaagaa tgccaatgcc tgcctgctgc ttcatgccgt
    47161 gttccctgca aagacccgtt aacggcattc acacagccac acgggtatat tttagtcggc
    47221 catcgaatgt aaaaagcccc gcaacaggtg cggggctttc atccgttacc ggaccacaaa
    47281 aaacttactc agcaacgatg ctgatgtatt tacggttttt cgggccttta acttcgaatt
    47341 tcactttacc gtctgcttta gcaaacagag tgtggtcacg accgcaacca acgttggtgc
    47401 cagcgtggaa tttagtacca cgttgacgaa cgatgatgct gcctgccaga actgcttcac
    47461 cgccaaagcg ttttacgccc agacgtttag cttcagaatc gcgaccgtta cgagtcgagc
    47521 cgccagcctt tttatgtgcc atttaatctg ctcccctaat cttaagcgct gatgccggta
    47581 attttcacat cagtgaacca ctgacgatgg ccctgctgct tacggtagtg tttacggcga
    47641 cgaaacttaa cgattttaac tttctcgcca cgaccgtggg caacaacttc agctttgatt
    47701 acgccgccat caacgaaagg aacgccgatt ttgacttctt caccgtttgc gatcatcaga
    47761 acttcagcga actcgatagt ttcgccagtt gcgatgtcca gcttttccag gcgaacggtc
    47821 tgaccttcgc ttactcggtg ttgtttacca ccactttgga aaaccgcgta cataaaaaac
    47881 tccgcttccg cgcacacctt tcaatgattc agagcgcgct ataaatattc acaatagggc
    47941 gcgaatatta cgcaaattgc acggctttga caagtgctac catcaataca tgaagaaaaa
    48001 aaaacacaac gcatacggta acgtttatct gcggcgtttt ttcagtacaa tcagggtata
    48061 tttctaacca taaaccctac gttacctcat tcagacatgg gataatcgga gcgataagcc
    48121 cggcttttgc gatgaattta gaaaaaatca acgagttaac cgcgcaagat atggcgggtg
    48181 tcaatgcgac aatccttgaa cagcttaatt ccgacgttca actgattaat cagctaggat
    48241 attacattat tagcggcggc ggaaaacgca ttcgtccgat gattgccgtt cttgccgcgc
    48301 gtgcggtggg ttatcagggt aacgcgcacg tgactatcgc cgctctgatc gagtttatcc
    48361 acacggcgac gctgctacat gatgatgtgg tggatgaatc tgatatgcgt cgcggcaaag
    48421 cgacggcaaa tgccgctttc ggtaatgccg ccagcgtgtt ggtcggcgac tttatctata
    48481 cccgcgcctt ccagatgatg accagcctcg gctcgttaaa agtgctggaa gtgatgtcgg
    48541 aagcggtcaa tgtgattgca gaaggcgaag tgctgcaatt gatgaacgtg aatgacccgg
    48601 acattaccga agaaaattac atgcgggtga tttacagtaa aacggcccgt ctgttcgaag
    48661 ccgccgccca gtgctccggt attcttgccg gttgtacgcc tgagcaagag aaagggttgc
    48721 aggactatgg ccgctacctt ggtacggctt tccagctcat tgacgatctg ctggattaca
    48781 gtgccgacgg cgagcatctc ggtaaaaatg tgggtgatga cctcaatgag ggcaaaccta
    48841 ccttaccgtt gcttcacgcc atgcgccacg gtacgccaga acagtcagcg atgatccgta
    48901 ccgctattga acaaggtaat ggccgtcatc ttctggaacc ggttctggaa gcgatgacca
    48961 cctgcggctc gctggaatgg acgcgtcagc gagcggaaga agaagccgac aaagcgatat
    49021 ccgcgttgca gatattgccg gataccccat ggcgtgaggc gctaatcggt ctcgcacaca
    49081 tcgcggtgca gcgcgatcgt tgatgccatt ctcttatccc gcgcactgcg cgggatatcc
    49141 cattaagttc taataaactc cagataccct attgcctgtc ttttcgtata ttcatatacg
    49201 gcttcccctg gcatattctg aatattgccg ccacttacat gaacttttta gaacattcct
    49261 tcacgaagcg ttatagtatc gaacgtcgtc gggttgttaa aaccgtaagt gattaatcta
    49321 aggagtgatg gatgtatgga aagcaagctt attgactggc atccggccga tatcattgcc
    49381 ggactacgta aaaaagggac ttcaatggcc gctgagtcac gccggaatgg attgagttca
    49441 tccacgctgg ccaatgcatt aacgcgcccg tggccgaaag gagagttgat tatcgcgaaa
    49501 gcattgggaa cggaaccctg ggttatttgg ccatcgcgtt atcacgatcc gcgcacgcat
    49561 gagtttatcg acagaacgcg gcttatgaga gcgcgtaata aagacaaaca gaatgtagag
    49621 taagtgcctg taaaacaacc cccgcaatcg cgttcgcggg ggttattcag cgtacagaag
    49681 gttattcgcc tttcacgcgt tcaatattcg cgcctagcgc gcgcagtttg tcttcgatgc
    49741 gctcataacc gcgatcgatg tgataaatgc gatccacaat cgtcgtgcct tccgcaatac
    49801 agcccgccag caccaggctc gcagatgccc gcagatctgt cgccatgacc tgggcgccag
    49861 agagcgtttc tacgccatgg catatgacgg tattgctttc aatttccgca cgcgcgccca
    49921 tgcggctgag ttcaggcacg tgcataaaac ggttttcaaa gacggtttca gtgataaagc
    49981 ccgtcccttc cgccaccagg ttcagcaacg tgaactgcgc ctgcatatcg gtcgggaatg
    50041 ccgggtgcgg cgctgtacgg acattgaccg ctttcggtcg tttgccgtgc atgtccagac
    50101 taatccagtc ctcgcccact tcgatatccg cgccagcatc gcgcagtttc gccagtaccg
    50161 cgtccagagt gtccggttgc gcgttacggc agaggatttt gccgcgagag atcgctgccg
    50221 ccaccaggaa agtccccgtt tcgatacgat ccggcagcac acgataaacg ccgccgccca
    50281 gacgctctac gccctcgatc gtaatacgat cggtgccctg cccggcgatc ttcgccccca
    50341 gcgtaactag gaagttagcg gtgtcgacaa tttccggctc gcgcgcggcg ttttcaatga
    50401 tggtcgtccc ttccgccagc gtagcggcgc acataatggt gacggtcgcg ccgacgctga
    50461 ccttatccat cacgatatgc gcccctttaa gacgtccttc gacggaggcc tttacgtagc
    50521 cctcttctag cttgatggtc gcacccagtt gttccagacc ggtaatatgt agatcaaccg
    50581 gacgcgcgcc gatagtacag ccccccggca gagagacttg tccctgacca aaacgggcaa
    50641 ccagcggccc cagcgcccat atcgaggcgc gcatggtctt aaccagatca taaggcgcgc
    50701 agaacacgtt cacctggctg gcgtcaatgt gtaccgatcc attgcgttcc actttcgcgc
    50761 ctaattggct caggagcttc atcgacgtat ccacgtcttt cagttttgga acgttttgga
    50821 tctctaccgg ttcttctgcc agcagagcgg cgaacaggat cggcagcgcg gcgtttttgg
    50881 cgccggaaat tgtgacttcg ccctggagcg tcgttggccc ctgtacacga aatttatcca
    50941 ttattgtatt ctcagttaag cattcatctc cgctaccggc aggttacccg tagcttaaaa
    51001 tccgttaagt ttacgatcgc gcgcccattc cgccggggta tatgctttga tcgatacggc
    51061 atggatacgg ttgtccgcaa tgtactccat tagcggccca tagaccgttt gctgtttctt
    51121 gacccggctc atgccgtcaa acatctcgcc cacggcaata acctgaaagt gactgccatc
    51181 gccggagacg tggacttcct ggagggagag ggcattcatc agcacactct gaatttcatg
    51241 attttccatg ggttctttat tcgtcaaata gtgaaaacag cccaacatct tagagcaaag
    51301 tcgcgccgtc ttaaataagc aaaagattac gctgataaat cagcgcggta aaagtgccgg
    51361 atggtgctgc taacgcaatt tatccggcct acggggatca tgcgaagtgt aggccggata
    51421 aaccatccgg cattcattac atacggggaa gtacgtcttc aggcaagtta tataattgcg
    51481 ccagcgcgta aaccttgtcg ttaacgccag acagcgacac ggcattgccc tgcttttttg
    51541 cctggttcac aaggtgcgcc agcagcgcca gtccccccgt atctaccctg gagatctggc
    51601 tcaggtcgat acgggtaacg ccattcatcg cttctacgcg cgcgtcccat agcggcgcca
    51661 acacgtcctg atccagctct cccgccagca ccagagtgtc cgcctcacgc gtccaggtga
    51721 gttgcggcgt cattactgtt tctcgtccaa agtaattttc tgttgagaga tagatttcag
    51781 ttgtgcggtc aggccgtcga tgcctttagt acgcagcaga tcgctccact cattttgctt
    51841 ggtggtgatc atgctgacgc cttccgcaat catgtcatac gcctgccagt tgccggtctg
    51901 agtgtttttg cgccactgga aatccaggcg taccggcgga cgaccgttgg gatcgataat
    51961 cgttacacgg ataggcacaa tggtcgcatc gcccagcggt tgctcaggcg ctatctggta
    52021 agtctggccg tggtacatcg ccagcgcctg accgtatgcc tgtttcaggt attcgcgaaa
    52081 cgctgcaaaa taggcttcac gctgcgccgg ggtcgcctct ttgtagtagc ggcccaacac
    52141 cagcgcgccg gcatatttta cctgcacgta cggcagaagt tcctgatcaa caacgtctcg
    52201 caggtaatcc ggattggcac gaattttcgg ctgttcgttt ttcaggcgat caaaagtttt
    52261 ctgcgccgcc tcgttcatca gtttataagg attgctctga tccgctgccg ttgctgcgct
    52321 taatggcgca atgaccagca gggccaccat catcagtcgt ttaaacatgc ctcaattctc
    52381 ctgagattat ttcgtttcgc ccgcgggcgt tgtggcttca gtatggcctt ccgttgcggc
    52441 tggcgcatcg ccagaattct tattgtcgtc gcctttgctg ttataaagga actggccaat
    52501 catatcttcc agcaccattg cagacttggt gtcctgaatc gtactcccat ctttgaggat
    52561 agacgttccc agctcaggat cttcaaaacc gacgtttaat gccagatatt gctcccccag
    52621 cagcccggaa gtacgaatac tcaacgagct ggtatcggga atatggttat aacgctcttc
    52681 gatgtcgagc gttacgcgcg gcaggtatgt tttcggatca agcgagatat cttcaacccg
    52741 cccgacaacc accccgccga tgcgtaccgg ggaacgcact ttcagaccgc cgatgttatc
    52801 gaaggtcgca taaaccttat aggtcggctc cgtgcgcata gaggtcacat ttgccgcctt
    52861 caggcaaaca aacagcgccg ccagcaacgc taccagcaaa aaaacgccta cccaaatttc
    52921 attttttttc gtttgcatga actcaattcc caaacatcag tgcggtcagc acaaaatcca
    52981 gccccagaac ggccaacgat gcgtgaacca cggtacgcgt cgttgcccgg ctaatcccgg
    53041 cagaagtcgg tattgcgtca taaccgttga ataacgcaat ccatgttacc gtaatggcga
    53101 acaccacgct ctttatcaga cagttcacca ggtccatacg ccagtcgacg gcattctgca
    53161 tcgcggacca gaagaacccg gcgtcgattc ccttccagct tacgccgacc agcgagccgc
    53221 cccagatacc gaccgccaca aagataatgg tcagtagcgg caatgaaatc acgcccgccc
    53281 aaaagcgcgg cgaaatcacc cggcgcaatg gatcgaccgc catcatctcc atactggaga
    53341 gctgctccgt cgcccgcatc aggccgattt ccgccgtcaa cgccgacccg gcccgcccgg
    53401 caaacagcaa cgccgcgacc accggcccca gctcgcgcag cagcgaaagc gccactaaca
    53461 tgccaagact ggtctccgcg ctgtaagtgg tcagaaccag atagccttgc agccccagca
    53521 ccataccgat gaatacgccg gagacaataa tgataagcat cgacaagacg cccacattat
    53581 aaagctggcg caccagcagc ggcgcatgtt tgcgaaactc cggcttaccg ataatcgcat
    53641 tgaataacat taacccggcg cgcccgaacg tcctgacggt tttgatcccg ctgtgtccga
    53701 gtgctgccag cgcatttaac agcatgagtg gcttaactcc ctgtttcgag taaatcaagg
    53761 tgatagtcgc ccgccggata gcggaacgga accggcccgt cggcaatacc gtcaaggaac
    53821 tgacgcacgc gcgggtccgt attctcctgc aacgcctgag cgctaccgtg agcgacgatt
    53881 tttttgtccg ccatgatcca ggcgtgatcc gcaatactga gcacctctgg cacatcatgc
    53941 gagaccacca cgcaggtcac gcccagcgcg ctgttcaatt ctgaaatcag cttcaccaga
    54001 acgcccatgg taatcgggtc ctggccaaca aacggctcat cgaacatgat gagatccggt
    54061 tccagagcga tggcgcgcgc caacgcggcg cggcgcgcca tcccaccgga gagctcggaa
    54121 ggcatcagtt ttgccgcgcc gcgcagcccg acagcttcca gtttcatcat cacgacgctt
    54181 tttagcagcg gcgcgggtaa attggtgtgc tcccgtagcg gataggccac attgtcaaac
    54241 acgttcatgt cggtaaacag cgctcccgac tgaaacagca tactcatacg tttacggacg
    54301 gtgtagagcc gcgaacggga catggccggc acattctcgc catcaaataa gatctcgccc
    54361 ttatccggcg ggatctgtcc gccaatcagg cgcaacagcg tggttttacc gatgcccgac
    54421 ggccccatga tcgccgtgat cttcccgcgc ggcaccgtca gggaaatatt atcgaaaatg
    54481 cagcgttcgc cacggcaaaa gctgacgtcg cgcatatcga ctaaattggc cgcagactga
    54541 cccattgatt catccttcgt attgccttgt tgaggtaacc atggcgctga atttaaccat
    54601 gggttcgaca taattacaga atattaactg acagggttag cgaaagctgg cattcgtttt
    54661 actttttagc cgcataaagt caaaattagg acttcgttac ggcttccaga tatcccttcc
    54721 aggggaccgg cgagtatacc tgaagaaagg actttagatg cttttagcga tggcgctact
    54781 cataattggt ttgcttctgg tggcctacgg cgccgatcgt ctggtgtttg cggcctctat
    54841 tttatgccgt acattcggta ttcccccgct gatcatcggg atgacggtcg tgagtatcgg
    54901 cacctcgctg ccggaaatta ttgtgtcggt cgccgcatcg ctacacggtc agctcgattt
    54961 ggccgtcggc gcggcgctcg gttctaacat caccaatatt ttgctgatct tagggctggc
    55021 ggcgctggtt cgtccattta ccgtgcattc cgatgttcta cgtcgcgaat tgccattaat
    55081 gttatttgtt agcgtggtag ccggttccgt actgcatgac ggacagttaa gtcgcagtga
    55141 tggtatcttt ctcctgcttc tggctgtgct atggctgtta ttcattgtta aaatcgcgcg
    55201 tctggccgaa cgccagggga atgacagcct cacccgcgaa caactggcgg agctgccgcg
    55261 cgaagacggg ctccccgtcg cgttcttatg gctgggcatt gcgctggtca tcatgccgat
    55321 ggcgacgcgc atggtaatcg ataacgctac ggtgctggcg aactatttcg ccatgagtga
    55381 attaacgctc ggtctgacag tcatcgccgt cggcaccagt ctgccagaac tggcgacggc
    55441 gattgccggc gtgcgaaaag gcgaaaatga tattgccgtt ggtaatctca ttggcgccaa
    55501 tatttttaat ctcgccatcg tgctgggact gcctgcgctg atcgcgccgg gggagatcaa
    55561 cccgctggcg tttgggcgtg attatagcgt gatgttgctg gttagcgtgg ttttcgcttt
    55621 actttgctgg cggcatccgc gccagattgg ccggggcgca ggtatactgc tgaccggcgg
    55681 gtttatcgta tggctggcga tgctctattg gctatcgcca cttcttgttg gataactgga
    55741 aacggattat gtcgcattta gcgttgcaac cggggtttga ctttcagcag gcaggcaaag
    55801 aggtcctgga aattgaacgt gaaggcctgg cggagcttga tcaatatatc aaccagcatt
    55861 tcacgctggc ctgtgaaaaa atgttcaact gcaccggaaa agtggtggtc atggggatgg
    55921 ggaaatccgg ccatatcgga cggaaaatgg ccgccacgtt cgccagtacc ggcacctctt
    55981 ccttttttgt acatccaggc gaagccgcgc acggcgattt ggggatggtt acgccgcagg
    56041 atgtggttat cgctatctcc aactccggcg aatccagcga gatcgcggcg ctaataccgg
    56101 tgcttaaacg gctgcacgta ccgttaattt gcattaccgg gcgaccggaa agcagcatgg
    56161 cgcgtgcggc agatgtgcat ctatgtgtta aagtgcccaa agaagcgtgt ccgttaggcc
    56221 tggcgcctac cagtagtacc accgcaacgc tggtgatggg cgacgcgctc gccgtggcgt
    56281 tgttaaaagc gcgcggcttt accgccgagg atttcgctct gtcgcatcct ggcggcgcgc
    56341 tgggacgtaa gctactgctg cgcgtaagcg atattatgca tactggcgat gagatcccgc
    56401 atgttaataa acatgccacc ctgcgtgatg cgctgttaga aattacgcgt aaaaatctcg
    56461 gtatgaccgt catttgcgat gaatccatga agatcgacgg tatcttcacc gacggcgatt
    56521 tacgtcgcat gttcgatatg ggcggcgata tgcgccagtt ggggatcgcc gaggtgatga
    56581 cgccaggggg cattcgcgtg cgtcccggta ttctcgctgt cgatgcgctg aatttaatgc
    56641 agtcccgcca tatcacctcc gtactggttg ctgatggcga ccagttactc ggtgtgttac
    56701 atatgcatga tctcctgcgt gcaggcgtcg tgtagaaact caaggataat taacgatgag
    56761 taaagcaggt gcgtcgcttg cgacctgtta tggccccgtc agcacccatg tcatgaccaa
    56821 agcggagaat atccgcctgc tcatcctgga cgtggatggc gtattgtctg acggcctgat
    56881 ttatatgggc aataacggcg aagagctgaa ggctttcaac gttcgtgacg gctatggtat
    56941 tcgctgtgct ttgacctcca atatcgaggt tgccattatt accggacgaa aggctaaact
    57001 tgtagaagat cgctgcgcca cgctggggat tgtccatctt tatcagggac agtcgaataa
    57061 gctgatcgcc tttagcgatc tgctggaaaa actggccatt gcgccggaaa atgttgccta
    57121 tgtcggcgat gatctgattg actggccagt gatggaaaaa gtggggttaa gcgttgccgt
    57181 tgcggatgcg catccgctgc tgatcccccg cgctgactat gtgacgcaca ttgccggcgg
    57241 gcgcggcgcg gtacgtgagg tgtgcgattt gctgctgctg gcgcagggca agctggatga
    57301 ggccaaaggg caatcgatat gagtaaaacc agacgttggg ttatcattct actgtcgctg
    57361 gctattctgg tactgattgg tatcaatctg gcggataaag acgatcctgc tgccgtgatg
    57421 gtcaacagca acgatcccac gtataaaagc gagcacacgg ataccgtcgt gtacagtccg
    57481 gaaggcgcgt tgagctatcg tctgatcgcg cagcacgttg aatatttttc cgatcaggcg
    57541 gtctcatggt ttacgcaacc ggtattaacc acctttgata aggataaagt gccgacatgg
    57601 tcgatcaagg ccgataaagc caaattgact aacgatcgga tgctctatct gtatggccat
    57661 gttgaagtca acgccctggt gcctgacgct caattacgca gaattaccac cgataacgcg
    57721 cagattaatc tggtgacgca ggatgttacc tcgaacgatc tggtgacgtt atacggcaca
    57781 acatttaact ccagcggact gaaaatgcgc ggtaacttac gcagcaagaa cgccgagctg
    57841 attgaaaagg ttagaacctc ttatgaaatt caaaacaaac aaactcagcc ttaatcttat
    57901 gcttgccggc tcgctgctgg ccgccagcat tccggccttc gccgtcacgg gcgataccga
    57961 acagcctatt catattgact cggatcaaca gtcactggat atgcaaggca acgtcgtgac
    58021 ctttacgggc aacgtggtaa tgacccaggg cacgattaag atcaacgccg ataaagtcgt
    58081 ggttacccgc cctggcggcg aacaggggaa agaggtgatc gacggttacg gcaatccggc
    58141 caccttctac cagatgcagg acaacggtaa gccggtgaaa ggccacgctt cccatatgca
    58201 ttacgagctg gcgaaagatt ttgtggtgct gaccggcaac gcttatctgg agcagcttga
    58261 cagcaacatt accggcgaca aaatcaccta cctggtgaaa gagcagaaaa tgcaggcctt
    58321 cagcgagaaa ggcaaacgcg tcaccaccgt tctggtgccg tcgcagttgc aagacaaaaa
    58381 caaaggccag actccggcgc aaaagaagag taactaattc gttatggcaa cattaactgc
    58441 aaagaatctg gcgaaggcct ataaaggccg tcgcgtagtg gaagatgtca gtctgaccgt
    58501 taactccggg gagattgtcg ggctgctcgg tccaaacggc gcgggtaaaa ccaccacctt
    58561 ttatatggtc gtcggtatcg tgccgcgtga cgcgggcaat atcatcatcg atgatgaaga
    58621 tatcagtctg ctgccgctgc acgcgcgcgc gcgccgcggt atcggctatt tgccgcagga
    58681 agcctctatt ttccgccgtc tcagcgtatt tgataacctg atggcggtac tgcaaattcg
    58741 tgacgatttg accgcagaac agcgagaaga ccgcgccaac gagctgatgg aagagtttca
    58801 tatcgagcat ctgcgcgaca gcatgggaca ggcgctgtcc ggtggtgaac gccgtcgtgt
    58861 agaaatagcc cgcgcgttgg ccgctaatcc caaatttatc ctgctggatg aaccctttgc
    58921 cggcgtcgac ccgatttccg ttatcgacat aaaacgcatt atcgagcatc tgcgcgatag
    58981 tgggctcggc gtgctgatca ccgaccataa cgtccgtgag acgctggcag tctgtgaacg
    59041 tgcctatatc gtgagccagg gccaccttat tgcccacggt acgccgacag aaatcctgca
    59101 agacgaacac gttaagcgtg tatatcttgg ggaagacttc agactctgat agggtagagg
    59161 gctatgctgc tctagcggga gaaaacgact ctgaatatga agcaaggttt gcaactcagg
    59221 cttagccaac aactggcgat gacgcctcag ctacaacagg ccatccgtct gttgcagttg
    59281 tctacgctgg aacttcagca ggaactccag caagcgctgg aaaataaccc gctgcttgag
    59341 caaaccgatc ttcatgacga aatcgacact cagcaacctc aggatgacga tcctctcgat
    59401 accgccgacg cgctcgaaca aaaagagatg ccggaagagc tgccgcttga cgccagttgg
    59461 gatgaaattt acaccgccgg gacgccgtcc ggccccagcg gcgattatat cgacgatgag
    59521 ctgcccgtct atcagggcga aacgacgcag tcgttgcagg attatctgat gtggcaggtt
    59581 gagctaacgc ccttctcgga caccgatcgc gctattgcga catccattgt cgacgcggta
    59641 gatgataccg gctatctcac cgtatccctg gacgaaattc gcgaaagcat gggcgatgta
    59701 gaggtggatc tcgatgaggt cgaagccgtc ctgaagcgta ttcagcgttt tgatccggta
    59761 ggcgtcgcgg caaaagatct tcgcgactgt ctgctgatcc agctttcaca attcgacaaa
    59821 tccacgccgt ggctggaaga ggcgcggctt attatctgcg atcaccttga tctgctggcc
    59881 aaccacgatt tccgcacgtt gatgcgcgtt acccgactaa aagaagaggt gctgaaagag
    59941 gcggtaaacc tgattcagtc gctcgatccc agacccggtc aatcgatcca gaccggcgag
    60001 ccggagtacg ttatcccgga tgtgctggta cgcaagcata acggtcgctg gacggtggag
    60061 cttaatagcg acagtattcc ccgtttacag attaaccagc actatgccgc catgtgcaat
    60121 agcgcgcgca acgatgccga cagccagttc atccgcagta atttacagga tgcgaaatgg
    60181 ctgataaaaa gccttgaaag ccgtaacgac acgctgctgc gcgtcagtcg ctgcatcgtc
    60241 gagcaacagc aagccttttt tgaacagggc gaagaatata tgaaaccgat ggtactggcg
    60301 gatatcgccc aggccgtcga gatgcacgaa tccactatat cccgcgtgac cacgcagaag
    60361 tatttgcaca gcccgcgcgg tatttttgaa ctcaaatatt tcttttccag ccacgtcaat
    60421 accgaaggcg gaggcgaagc ctcttccacc gcgattcgcg cgctggtgaa gaagttaatt
    60481 gcggcggaaa accccgcgaa accactgagc gacagcaagt taacctctct gctgtcagaa
    60541 caaggtatca tggtggcacg ccgcactgtt gcgaagtacc gagagtcttt atccattccg
    60601 ccgtcaaacc aacgcaaaca gctggtttga cccaaccgat aaggaagaca ctatgcagct
    60661 caatatcacc ggacataacg tcgaaattac tgaagccctg cgtgaatttg tgacgacgaa
    60721 attcgccaaa cttgaacagt attttgagcg gattaatcag gtatacgtgg tgttgaaagt
    60781 ggagaaggtc acgcacatct cggatgcgac gctacacgtt aacggcggcg aaattcacgc
    60841 cagcgcggaa ggccaggata tgtatgccgc cattgacggc ttgattgata aactggcaag
    60901 gcagttaacc aagcataaag ataaactgaa acaatactaa ttgtccgggc agttagccag
    60961 tgcaggacgg cctgttgtgt gacacaacgg gccatttgta cagttagcgc tccgaacctg
    61021 gccatcaacc tgacaggaca ggttcttagg tgaaattatg ataaataacg atacgactct
    61081 acaactgagc agtgtactta accaggagtg tacgcgtagc ggcgttcatt gtcagagtaa
    61141 gaaacgcgcg ctggaaatca tcagcgaact ggcggcaaaa cagctcagtt tacctcctca
    61201 ggtcgtgttt gaagccattc tgacacgcga aaaaatgggc agtaccggta ttggtaatgg
    61261 tatcgccatc ccgcacggga aactggaaga agatacctta cgcgccgtcg gcgtgttcgt
    61321 tcagctcgaa acgccgatcg cgttcgacgc catcgataac cagccggtcg atctcctctt
    61381 cgctctgctg gtgcccgccg atcaaactaa aacgcatctg cacacgctgt cgctggtggc
    61441 gaaacgtctg gcggataaaa cgatctgccg ccgcctgcgc gcggcgctga atgatgaaga
    61501 gctgtatcaa atcattactg acaccgaagg tgagcagaat gaggcataac aactcaatgg
    61561 catttatttc tgtcgttgtg aggagaaacg gtacatggta ctgatgatcg tcagcgggcg
    61621 ttccggatca ggtaaatctg tcgctctgcg cgcgctggaa gatatgggat tttactgcgt
    61681 ggataacctc cccgtcgtgc tgttgcccga tctggcgcga acgctggccg atcgccagat
    61741 ttccgccgcc gtcagcattg atgtgcgcaa tatacctgaa tcacctgaga tttttgaaca
    61801 ggcgatgaat aatctgcctg gcgctttctc gccgcaattg ctgtttcttg atgccgaccg
    61861 caataccttg attcgccgct acagcgacac gcgccgtttg catccgcttt ccagcaaaaa
    61921 tctttctttg gagagtgcga tcgataaaga gagtgacttg ctggagccgt tacgctcacg
    61981 tgcggatctg atcgtcgaca cttcagaaat gtccgtccat gagctggcgg agatgctgcg
    62041 tacccggcta ttgggcaaac gcgagcgcga actgacgatg gtatttgagt ccttcggctt
    62101 taaacatggt atcccgattg atgcggacta tgtgtttgat gtccgctttc tgcccaaccc
    62161 acactgggac ccaaaactgc gccccatgac cgggcttgat aagccggtag ccgcgtttct
    62221 tgaccgacac acagaagttc acaattttat ctatcagact cgcagctatc ttgagctatg
    62281 gttaccgatg ctggagacca acaaccgcag ctaccttacc gtcgctatcg gttgtaccgg
    62341 cgggaaacac cgttcggtgt atattgcaga acagctggca gactacttcc gctcgcgcgg
    62401 taaaaatgtc cagtctcgcc atcgcacgct ggaaaaacgc aaaacatgac cgtaaagcaa
    62461 actgttgaag tcaccaataa gctgggcatg catgcccggc ctgccatgaa gcttttcgaa
    62521 ctgatgcagg gttttgacgc cgaggtgcta ttacgcaatg acgaaggcac cgaagcggaa
    62581 gcaaacagcg tcatcgctct gttaatgctc gactccgcca aagggcgtca gatcgaaatt
    62641 gaagccaccg gcccgcaaga agttgaagcg ctggcggcgg ttatcgcgct gttcaattcc
    62701 ggctttgacg aagactaaac ctccccctct ataccctatt taccccaacg ccgtcccggt
    62761 atttgatggc agtcccccca aaaccggacg tgttacgcct gcctcttgtc ccgcagcccc
    62821 accctttcgt aaggtttgta catttcgtgc gctttaatta tgcataaaaa cattaagaaa
    62881 acc
//
LOCUS       DAJVBX010000003        61817 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.003, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000003 DAJVBX010000000
VERSION     DAJVBX010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 61817)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61817)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61817
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.003"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..2343
                     /locus_tag="OPV72_000125"
     CDS             <1..2343
                     /locus_tag="OPV72_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroloquinoline quinone-dependent
                     dehydrogenase"
                     /protein_id="HCR9912546.1"
                     /translation="ALFAALCGLYLLIGGVWLVAIGGSWYYPIAGLVMLVVAGLLWRS
                     KRAALWLYAALLLATMIWGVWEVGFDFWALTPRSDILVFFGIWLILPFVWHRLVVPSS
                     GAVAALVVALLISGGILTWAGFNDPQEINGTLRADATPAATSSSIADEDWPAYGRNQE
                     GQRYSPLKQITADNVHQLKEAWVFRTGDLKQPNDPGEITNEVTPIKVGDTLYLCTAHQ
                     RLFALDAASGKEKWHFDPQLKTDSSFQHVTCRGVSYHEAKADTASPEVIADCPSRIIL
                     PVNDGRLFAVNAETGKLCETFANKGVLNLQTNMPDTTPGLYEPTSPPIITDKTIVIAG
                     SVTDNFSTRETSGVIRGFDVNSGKLLWAFDPGAKDPNTIPADEHAFTFNSPNSWAPAA
                     YDAKLDLVYLPMGVTTPDIWGGNRTPEQERYASSILALNATTGKLAWSYQTVHHDLWD
                     MDLPAQPTLADITVDGTTVPVIYAPAKTGNIFVLDRRNGELVVPAPEKPVPQGAAKGD
                     YVAKTQPFSDLTFRPKKDLSGADMWGATMFDQLVCRVMFHQLRYEGIFTPPSEQGTLV
                     FPGNLGMFEWGGISVDPDRQVAIANPMALPFVSKLIPRGPGNPMEPPKDAKGTGTEAG
                     IQPQYGVPFGVTLNPFLSPFGLPCKQPAWGYISALDLKTNEIVWKKRIGTPRDSMPFP
                     MPVPVPFNMGMPMLGGPISTAGNVLFIAATADNYLRAYNMSNGEKLWQGRLPAGGQAT
                     PMTYEVNGKQYVVISAGGHGSFGTKMGDYIVAYALPDDAK"
     gene            complement(2421..4031)
                     /gene="cueO"
                     /locus_tag="OPV72_000126"
     CDS             complement(2421..4031)
                     /gene="cueO"
                     /locus_tag="OPV72_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multicopper oxidase CueO"
                     /protein_id="HCR9912547.1"
                     /translation="MLRRDFLKYSVALGVASALPLWSRAAFAAERPALPIPDLLTADA
                     SNRMQLIVKAGQSTFAGKNATTWGYNGNLLGPAVQLHKGKSVTVDIHNQLAEDTTLHW
                     HGLEIPGIVDGGPQGIIPAGGTRTVTFTPQQRAATCWIHPHKHGKTGRQVAMGLAGLV
                     LIEDDEIRKLRLPKQWGIDDVPVIIQDKRFSADGQIDYQLDIMTAAVGWFGDTLLTNG
                     AIYPQHSAPKGWLRLRLLNGCNARSLNIAASDNRPLYVIASDGGLLAEPVKVTELPLL
                     MGERFEVLVDISDGKAFDLVTLPVSQMGMAIAPFDKPHPVMRIQPLRITASGTLPDTL
                     TTMPALPSLEGLTVRNLKLSMDPRLDMMGMQMLMKKYGAQAMSGMDHDSMNAHMQGGN
                     MGHGEMDHGNMDHSGMNHGAMGNMNHGGKFDFHNANFINGQVFDMNKPMFAAQKGRHE
                     RWVISGVGDMMLHPFHIHGTQFRILSENGKAPAAHRTGWKDTVRVEGGISEVLVKFDH
                     DAPKEHAYMAHCHLLEHEDTGMMLGFTV"
     gene            4233..4580
                     /locus_tag="OPV72_000127"
     CDS             4233..4580
                     /locus_tag="OPV72_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YacC family pilotin-like protein"
                     /protein_id="HCR9912548.1"
                     /translation="MKTFFRPVLFGSLMALCANSYALTESEAEDMADLTAVFVFLKND
                     CGYQNLPNSQIRRALVFFAQQNQWDLSNYDTFDMKSLGEDSYRDLSGIGIPVAKKCKA
                     LARDSLSLLAYVK"
     gene            4687..5547
                     /gene="speE"
                     /locus_tag="OPV72_000128"
     CDS             4687..5547
                     /gene="speE"
                     /locus_tag="OPV72_000128"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HCR9912549.1"
                     /translation="MAENTMWHETLHDQFGQYFAVDNVLYHEKTDHQDLIIFENAAFG
                     RVMALDGVVQTTERDEFIYHEMMTHVPLLAHGHAKHVLIIGGGDGAMLREVTRHKNVE
                     TITMVEIDAGVVSFCRQYLPNHNAGSYDDPRFTLVIDDGVNFVNQTHQTFDVIISDCT
                     DPIGPGESLFTPAFYEGCKRCLNPGGIFVAQNGVCFLQQDEALDSHRKLSHYFSDVGF
                     YQAAIPTYYGGIMTFAWATDNDALRHLSSEIIQARFHAAGLKCRYYNSAIHAAAFALP
                     QYLHDALSAQ"
     gene            5568..6362
                     /gene="speD"
                     /locus_tag="OPV72_000129"
     CDS             5568..6362
                     /gene="speD"
                     /locus_tag="OPV72_000129"
                     /EC_number="4.1.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine decarboxylase"
                     /protein_id="HCR9912550.1"
                     /translation="MKKLKLHGFNNLTKSLSFCIYDICYAKTAEERDGYIAYIDELYN
                     ANRLTEILSETCSIIGANILNIARQDYEPQGASVTILVSEEPIDPKLIDQTEHPGPLP
                     ETVVAHLDKSHICVHTYPESHPEGGLCTFRADIEVSTCGVISPLKALNYLIHQLESDI
                     VTIDYRVRGFTRDVNGMKHFIDHEINSIQNFMSEDMKSLYDMVDVNVYQENIFHTKML
                     LKEFDLKHYMFHTKPEDLTETERQQITAALWKEMREIYYGRNISAV"
     gene            complement(6392..7159)
                     /locus_tag="OPV72_000130"
     CDS             complement(6392..7159)
                     /locus_tag="OPV72_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCR9912551.1"
                     /translation="MKGQHRLDLIVAYLKNHTLVTVEQLVEAVDASPATIRRDLIKLD
                     EQGVISRSHGGVALRRFEPAQPTTNEKQLRSPAEKRAIARVAASLVNAGDAVVLDAGT
                     TMMELAKCLTHLPLRVITVDLHIALFLAEFRQIEVTIVGGRIDDSSQSCIGEHGRKLL
                     RSVYPNIAFMSCNSWGVKTGVTTPTEDKAGLKQEIIANAQRKVLLADSSKYGAHSLFN
                     VVPLERFNDVITDVNLPPSAQVELKGRAFALTLVQPE"
     gene            complement(7169..8152)
                     /locus_tag="OPV72_000131"
     CDS             complement(7169..8152)
                     /locus_tag="OPV72_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-threonate 4-phosphate dehydrogenase"
                     /protein_id="HCR9912552.1"
                     /translation="METKTVAITMGDPAGIGPEIIVKALSEDGLNGAPLVVIGCLATL
                     KCLQAKGITPNVELRAIERVAEARFAPGIIHVIDEPLAQPEALEAGKVQAQAGDLAYR
                     CVKRATELALRGDVQAIATAPLNKEALHLAGHNYPGHTELLATLTHSRDYAMVLYTDK
                     LKVIHVSTHIALRKFLDTLSTTRVETVIGIADTFLKRVGYVKPRIAVAGVNPHAGENG
                     LFGDEETRILTPAITDARAKGMDVYGPCPPDTVFLQAYEGQYDMVVAMYHDQGHIPLK
                     LLGFYDGVNITAGLPFIRTSADHGTAFDIAWTGKAKSESMAVSIKLAMQLA"
     gene            complement(8142..9413)
                     /locus_tag="OPV72_000132"
     CDS             complement(8142..9413)
                     /locus_tag="OPV72_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-threonate kinase"
                     /protein_id="HCR9912553.1"
                     /translation="MKMMVIADDFTGSNDTGVQLAKKGARTEVMLSASQKPSRRADVL
                     VINTESRAMPADQAASAVYAALSPWCETSPAPLVYKKIDSTFRGNIGAEVTAAMRASQ
                     RKLAVIAAAIPAAGRTTLEGKCLVNGAPLLETEFASDPKTPIVSSRIAEIVALQSEIP
                     VYEVFLQDVRRGGLSALLTAYAAEGEGIIVVDAVEERDLTLIAQAACEQPSMPLLVGA
                     AGLANALPVELFMQDRQRLPVLVVAGSMSEATRRQVDNALCRGRAEVVDIDAARMVSD
                     SAEQEIASVVEQACALLSQHRHTILRTSRRAEDRQLIDALCEKSAMSRQQLGERLSHR
                     LGVVTLNIIEQARIGGLFLTGGDIATAVAGALGAEGYRIQSEVAPCIPCGTFVNSEID
                     DLPVITKAGGFGSDSTLCDALYYIEEMYCGD"
     gene            complement(9410..10363)
                     /locus_tag="OPV72_000133"
     CDS             complement(9410..10363)
                     /locus_tag="OPV72_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease 1"
                     /protein_id="HCR9912554.1"
                     /translation="MNIKKAIERVPGGMMVVPLVIGAVINTFAPQALEIGGFTTALFK
                     NGAAPLIGAFLLCMGAGISVKAAPQALLQGGTITLTKLLVAIGIGLGVEHLFGAEGIF
                     GLSGVAIIAAMSNSNGGLYAALVGEFGNERDVGAISILSLNDGPFFTMIALGAAGMAN
                     IPIMALVAVLVPLVVGMILGNLDPHMRDFLTKGGPLLIPFFAFALGAGINLEMLLQGG
                     LAGILLGVLTTFVGGFFNIRADRLVGGTGIAGAAASSTAGNAVATPLAIAQADPSLAE
                     VAAAAAPLIAASVITTAILTPVLTSWVAKKQARQASLEKNA"
     gene            complement(10598..10960)
                     /locus_tag="OPV72_000134"
     CDS             complement(10598..10960)
                     /locus_tag="OPV72_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YacL family protein"
                     /protein_id="HCR9912555.1"
                     /translation="MDYEFLRDVTGRVLVRMSMGHEVVGHWFNEEVKDNLSLLDEVEQ
                     AARTVKGSERSWQRAGHEYTIWMDGEEVMIRANQLDFSGDEMEEGMSYYDEESLSLCG
                     MEDFLRVVAAYREFVSKA"
     gene            complement(11148..13745)
                     /gene="acnB"
                     /locus_tag="OPV72_000135"
     CDS             complement(11148..13745)
                     /gene="acnB"
                     /locus_tag="OPV72_000135"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aconitate hydratase
                     2/2-methylisocitrate dehydratase"
                     /protein_id="HCR9912556.1"
                     /translation="MLEEYRKHVAERAAQGIVPKPLDATQMAALVELLKTPPVGEEEF
                     LLDLLINRVPPGVDEAAYVKAGFLAAVAKGDTTSPLVSPEKAIELLGTMQGGYNIHPL
                     IDALDDAKLAPIAAKALSHTLLMFDNFYDVEEKAKAGNEYAKQVMQSWADAEWFLSRP
                     PLAEKITVTVFKVTGETNTDDLSPAPDAWSRPDIPLHAQAMLKNAREGIEPDQPGVVG
                     PIKQIEALQKKGYPLAYVGDVVGTGSSRKSATNSVLWFMGDDIPNVPNKRGGGLCLGG
                     KIAPIFFNTMEDAGALPIEVDVSNLNMGDVIDVYPYKGEVRNHETDELLATFELKTDV
                     LIDEVRAGGRIPLIIGRGLTTKAREALGLPHSDVFRQAKDVAESSRGFSLAQKMVGRA
                     CGVKGIRPGAYCEPKMTSVGSQDTTGPMTRDELKDLACLGFSADLVMQSFCHTAAYPK
                     PVDVTTHHTLPDFIMNRGGVSLRPGDGVIHSWLNRMLLPDTVGTGGDSHTRFPIGISF
                     PAGSGLVAFAAATGVMPLDMPESVLVRFKGKMQPGITLRDLVHAIPLYAIKQGLLTVE
                     KKGKKNIFSGRILEIEGLPDLKVEQAFELTDASAERSAAGCTIKLNKEPIVEYLTSNI
                     VLLKWMIAEGYGDRRTLERRIQGMEKWLADPQLLEADADAEYAAVIDIDLADIKEPIL
                     CAPNDPDDARLLSDVQGEKIDEVFIGSCMTNIGHFRAAGKLLDSHKGQLPTRLWVAPP
                     TRMDAAQLTEEGYYSVFGKSGARIEIPGCSLCMGNQARVADGATVVSTSTRNFPNRLG
                     TGANVFLASAELAAVAALIGKLPTPEEYQTFVAQVDKTAVDTYRYLNFDQLSQYTEKA
                     DGVIFQTAV"
     gene            14134..15756
                     /locus_tag="OPV72_000136"
     CDS             14134..15756
                     /locus_tag="OPV72_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459162.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3300 domain-containing protein"
                     /protein_id="HCR9912557.1"
                     /translation="MTLPFKPHLIALVCSAGLFAASGVLYVKSRAPEAPAQAAAPTSE
                     PTQTAVPAPVAKTTFTTAQIDQWVAPVALYPDALLSQVLMASTYPANVVQAVQWSRDN
                     PTLQGDAAIQAVASQPWDPSVKSLVAFPQLMALMGENPQWVQNLGDAFLAQPQDVMDA
                     VQRLRLLAQQTGSLKSTPQQTVTSVPKSSASTAVTTTTTTSASTPATPSTVIKIEPAN
                     PQVVYVPNYNPTTVYGAWPNTAYPPVYLPPPPGQQFADSFVKGFGYSLGVATTYALFS
                     SIDWDDDDHHHHDDDHHDDDYHHGGNGYQHNGDNININVNNFNRISGQNLPGQTMGWQ
                     HNPAWRNGVPYPNNTVAQRFHPTNVSGGLSATQQAPVSRDSQRQAAMAQFQQRSHTSP
                     ANVSGETSRDRQRKAASQQLNQIAQRNNYRGYDGTQNSSRREAAQQTLNKSTTQQHRS
                     ELKAKAQQHPVSQQQRDTARQRIESSTPQQRQAFRQNMHANVFSGNDSRSPSWQSQQL
                     RGLESRRGSHLNTEQRAAAREHFSEHHEFHRR"
     gene            15769..16560
                     /locus_tag="OPV72_000137"
     CDS             15769..16560
                     /locus_tag="OPV72_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2950 family protein"
                     /protein_id="HCR9912558.1"
                     /translation="MKKVMLSALLLSLPLLGYAQERFPSPEAAASAFAAAVAGKNETQ
                     LTALLGDDWRQFLPPEGADPEAVARFNRDWREGHRIVQKDNTAHLNVGREDWQLPVPM
                     VKETGGWRFDMAAAGNEILTRTIGRNELSTLQAMHAYVDAQQDYYLQNHRWAHRIISS
                     EGQKDGLYWPTKAGDVPSPLGPNFSPAAPDEGYHGYHFRIISDNDGHGAALLAWPMHY
                     GETGVMSFMVNQDDRIYQADLGKETESKVQAITRFAPDAQWQVAE"
     gene            complement(16598..16882)
                     /locus_tag="OPV72_000138"
     CDS             complement(16598..16882)
                     /locus_tag="OPV72_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein"
                     /protein_id="HCR9912559.1"
                     /translation="MKLFLTTAALTATLISGMAFASDPVIPWATNSGGTESTHIAAMG
                     EDLNAQHQQITHTHEGVWAANSGSIQADEAALTSNKPPVQGHPELMPHQG"
     gene            complement(17171..18595)
                     /gene="lpdA"
                     /locus_tag="OPV72_000139"
     CDS             complement(17171..18595)
                     /gene="lpdA"
                     /locus_tag="OPV72_000139"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001738005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HCR9912560.1"
                     /translation="MSTEIKTQVVVLGAGPAGYSAAFRCADLGLETVIVERYNTLGGV
                     CLNVGCIPSKALLHVAKVIEEAKALAEHGIVFGEPKTDIDKIRTWKEKVITQLTGGLA
                     GMAKGRKVKVVNGLGKFTGANTLEVEGENGKTVINFDNAIIAAGSRPIQLPFIPHEDP
                     RVWDSTDALELKEVPKRMLVMGGGIIGLEMGTVYHALGSEIDVVEMFDQVIPAADKDI
                     VKVFTKRISKKFNLMLETKVTAVEAKEDGIYVSMEGKKAPAEAQRYDAVLVAIGRVPN
                     GKNLDAGKAGVEVDDRGFIRVDKQLRTNVPHIFAIGDIVGQPMLAHKGVHEGHVAAEV
                     IAGKKHYFDPKVIPSIAYTEPEVAWVGLTEKEAKEKGISYETATFPWAASGRAIASDC
                     ADGMTKLIFDKESHRVIGGAIVGTNGGELLGEIGLAIEMGCDAEDIALTIHAHPTLHE
                     SVGLAAEIFEGSITDLPNPKAKKK"
     gene            complement(18797..20686)
                     /gene="aceF"
                     /locus_tag="OPV72_000140"
     CDS             complement(18797..20686)
                     /gene="aceF"
                     /locus_tag="OPV72_000140"
                     /EC_number="2.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459158.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase complex
                     dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HCR9912561.1"
                     /translation="MAIEIKVPDIGTDEVEITEILVKVGDKVEAEQSLITVEGDKASM
                     EVPSPQAGVVKEIKVSVGDKTETGALIMIFDSADGAADAAPAQAEEKKEAAPAAAPAA
                     AAAKDVHVPDIGSDEVEVTEVMVKVGDTVEAEQSLITVEGDKASMEVPAPFAGTVKEI
                     KVNTGDKVSTGSLIMVFEVAGEAGAAAPAKAEAAPAAAAPAAATGVKDVNVPDIGGDE
                     VEVTEVMVKVGDKVTAEQSLITVEGDKASMEVPAPFAGTVKEIKISTGDKVKTGSLIM
                     VFEVEGAAPAAAPAKQEAAAPAPAAKAEKPAAPAAKAEGKSEFAENDAYVHATPLIRR
                     LAREFGVNLAKVKGTGRKGRILREDVQAYVKDAIKRAEAAPAAAGGGIPGMLPWPKVD
                     FSKFGEVEEVELGRIQKISGANLSRNWVMIPHVTHFDKTDITDLEAFRKQQNAEAEKR
                     KLDVKYTPVVFIMKAVAAALEQMPRFNSSLSEDGQRLTLKKYINIGVAVDTPNGLVVP
                     VFKDVNKKSVTELSRELTTISKKARDGKLTAGEMQGGCFTISSIGGLGTTHFAPIVNA
                     PEVAILGVSKSAMEPVWNGKEFVPRLMMPISLSFDHRVIDGADGARFITIINNMLSDI
                     RRLVM"
     gene            complement(20701..23364)
                     /gene="aceE"
                     /locus_tag="OPV72_000141"
     CDS             complement(20701..23364)
                     /gene="aceE"
                     /locus_tag="OPV72_000141"
                     /EC_number="1.2.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008814576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring),
                     homodimeric type"
                     /protein_id="HCR9912562.1"
                     /translation="MSERFQNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLSEA
                     RKGGVKVAAGAGASNYINTIAVEDEPEYPGNLELERRIRSAIRWNAIMTVLRASKKDL
                     ELGGHMASFQSSATIYDVCFNHFFRARNEQDGGDLVYFQGHISPGIYARAFLEGRLTQ
                     EQMDNFRQEVHGNGLSSYPHPKLMPEFWQFPTVSMGLGPIGAIYQAKFLKYLEHRGLK
                     DTSKQTVYAFLGDGEMDEPESKGAITIATREKLDNLVFVINCNLQRLDGPVTGNGKIV
                     NELEGIFAGAGWNVIKVMWGGRWDELLRKDTSGKLIQLMNETVDGDYQTFKSKDGAYV
                     REHFFGKYPETAALVADWTDEQIWALNRGGHDPKKVYAALKKAQETKGKATVILAHTI
                     KGYGMGDTAEGKNIAHQVKKMNMDGVRYVRDRFNVPVADADLEKLPYITFPEGSEEHK
                     YLHERRQALHGYLPSRQPNFTEKLELPQLSDFGALLEEQSKEISTTIAFVRALNVMLK
                     NKSIKDRLVPIIADEARTFGMEGLFRQIGIYSPNGQQYTPQDREQVAYYKEDEKGQIL
                     QEGINELGAGASWLAAATSYSTNDLPMIPFYIYYSMFGFQRIGDLCWQAGDQQARGFL
                     IGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCISYDPAYAYEVAVIMHDGLERMYGEK
                     QENVYYYITTLNENYHMPAMPAGAEEGIRKGIYKLETLEGSKGKVQLLGSGSILRHVR
                     EAAEILAKDYGVGSDVYSVTSFTELARDGQDCERWNMLHPLETPRVPYIAQVMNDAPA
                     VASTDYMKLFAEQVRTYVPADDYRVLGTDGFGRSDSRENLRHHFEVDASYVVVAALGE
                     LAKRGEIDKKVVADAITKFNIDADKVNPRLA"
     gene            complement(23524..24288)
                     /gene="pdhR"
                     /locus_tag="OPV72_000142"
     CDS             complement(23524..24288)
                     /gene="pdhR"
                     /locus_tag="OPV72_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase complex transcriptional
                     repressor PdhR"
                     /protein_id="HCR9912563.1"
                     /translation="MAYSKIRQPKLSDVIEQQLEFLILEGTLRPGEKLPPERELAKQF
                     DVSRPSLREAIQRLEAKGLLLRRQGGGTFVQSSLWQSFSDPLVELLSDHPESQFDLLE
                     TRHALEGIAAYYAALRSTDEDKDRIRELHHAIELAQESGDLDAESEAVLQYQIAVTEA
                     AHNVVLLHLLRCMEPMLAQNVRQNFELLYARREMLPLVSTHRTRIFEAIMAGKPEEAR
                     EASHRHLAFIEEIMLDRSREESRRERALRRLEQRKN"
     gene            24851..26224
                     /gene="aroP"
                     /locus_tag="OPV72_000143"
     CDS             24851..26224
                     /gene="aroP"
                     /locus_tag="OPV72_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic amino acid transporter AroP"
                     /protein_id="HCR9912564.1"
                     /translation="MMDSQQHGEQLKRGLKNRHIQLIALGGAIGTGLFLGSASVIQSA
                     GPGIILGYAIAGFIAFLIMRQLGEMVVEEPVAGSFSHFAYKYWGGFAGFASGWNYWVL
                     YVLVAMAELTAVGKYIQFWYPEIPTWASAAAFFVIINAINLTNVKVFGEMEFWFAIIK
                     VIAVIAMILFGAWLLFSDTAGPQATVRNLWEQGGFLPHGWTGLVMMMAIIMFSFGGLE
                     LVGITAAEADNPEQSIPKATNQVIYRILIFYIGSLAVLLSLLPWTRVTADTSPFVLIF
                     HELGDTFVANALNIVVLTAALSVYNSCVYCNSRMLFGLAQQGNAPKALLNVDKRGVPV
                     SSILVSAVVTALCVLLNYLAPESAFGLLMALVVSALVINWAMISLAHMMFRRAKQQQG
                     VKTRFPALFYPFGNVLCLLFMAAVLIIMLMTPGMAISVWLIPVWLLILGVGYLCKEKT
                     AKTVKAH"
     gene            26388..27794
                     /locus_tag="OPV72_000144"
     CDS             26388..27794
                     /locus_tag="OPV72_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR9912565.1"
                     /translation="MDKGRLSVREKIGYGMGDAGYNIIFGAIMLFVNYFYTDIFGLAP
                     ALVGVLLLSVRVIDAVTDPVMGALADRTQSKYGRFRPWLLWIAFPYALFSVLMFTTPD
                     WGYNSKVIYAFVTYFLLSVTYTAINIPYCSLGGVITNDPKERVACQAYRFVLVGIATL
                     LLSLTLLPMVDWFGDGDKAKGYQLAMTVLAIIGMGMFLFCFASVRERVRPAVPTHDDM
                     KNDFKDVWKNDQWVRILLLTLCNVCPGFIRMAATMYYVTWVMGQSTHFATLFISLGVV
                     GMMIGSMLAKVLTDRWCKLKVFFWTNIALAIFSCAFYFFDPKATVMIVALYFLLNILH
                     QIPSPLHWSLMADVDDYGEWKTGKRITGISFSGNLFFLKLGLAIAGAMVGFLLSWYGY
                     DASAKAQSASAMNGIMLLFTVILGVGYLITAGVVRLLKVDRELMKKIQDDLEKRRTNY
                     RELSELQELKAAESVRKA"
     gene            27794..28744
                     /locus_tag="OPV72_000145"
     CDS             27794..28744
                     /locus_tag="OPV72_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HCR9912566.1"
                     /translation="MANWPNPFIEQRADPFILRDGSDYYFIASVPEYDRLEIRRADSL
                     EGLRAADPVVVWRKPESGPMSQLIWAPEMHRINGKWYIYFAATHTQALDKLGMFQHRM
                     FALECADADPLTGKWTEKGQIKTPFDTFSLDATTFYHQGKQWYLWAQKAPDIAGNSNI
                     YLAELENPWTLKGEPVRLSKPEYDWECRGFWVNEGPAVVVHGDKLFISYSASATDENY
                     CMGLLWINVNDDPRDPANWHKSPRPVFTTSYENRQYGPGHNSFTQTSEGEDVLVYHAR
                     NYTEIEGDPLYDPNRHTRLKRVRWDENGMPDFGVPPADTI"
     gene            complement(28836..29690)
                     /gene="ampE"
                     /locus_tag="OPV72_000146"
     CDS             complement(28836..29690)
                     /gene="ampE"
                     /locus_tag="OPV72_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase regulator AmpE"
                     /protein_id="HCR9912567.1"
                     /translation="MTLFTTLLVLIVERLFKLGEHWQLDHRLEALFRRITHFSMLRTM
                     GMTAIAMVVTFLLLQALKGLLFNVPTLVVWILLGVLCIGAGKVRVHYHAWLKAASRND
                     PHPCEAMASELTLIHGVPPDCNEREFLRELQNALLWINFRFYLAPLFWFIVGGPWGPV
                     TLVGYAFLRAWQTWLARYQTPHQRLQSGIDAILHVLDWIPVRLAGVVYALLGHGEKAL
                     PAWFASLADLHTSQYQVLTRLAQFSLVREPHTDKVETPKAAVSMAKKASFVVVVIIAL
                     LTIYGALV"
     gene            complement(29687..30250)
                     /gene="ampD"
                     /locus_tag="OPV72_000147"
     CDS             complement(29687..30250)
                     /gene="ampD"
                     /locus_tag="OPV72_000147"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,6-anhydro-N-acetylmuramyl-L-alanine amidase
                     AmpD"
                     /protein_id="HCR9912568.1"
                     /translation="MLPDKGWLVEARRVPSPHYDCRPDDEKPSLLVVHNISLPPGEFG
                     GPWIDALFTGTIDPDAHPFFAEIAHLRVSAHCLIRRDGEIVQYVPFDKRAWHAGVSNY
                     QGRERCNDFSIGIELEGTDTLAYTDAQYQQLAAVTRTLIACYPAIADNMTGHCNIAPD
                     RKTDPGPAFDWPRFRALVALSSHKEMT"
     gene            30338..31231
                     /gene="nadC"
                     /locus_tag="OPV72_000148"
     CDS             30338..31231
                     /gene="nadC"
                     /locus_tag="OPV72_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HCR9912569.1"
                     /translation="MPPRRYNPDDRRDALLERINLDIPAAVAQALREDLGGEVDAGND
                     ITAQLLPADTQAHATVITREDGVFCGKRWVEEVFIQLAGDDVRLTWHVDDGDAIHANQ
                     TVFELNGPARVLLTGERTALNFVQTLSGVASEVRRYVGLLAGTQTQLLDTRKTLPGLR
                     TALKYAVLCGGGANHRLGLTDAFLIKENHIIASGSVRQAVEKAFWLHPDVPVEVEVEN
                     LDELDDALKAGADIIMLDNFNTDQMREAVKHVNGQARLEVSGNVTAETLREFAETGVD
                     FISVGALTKHVRALDLSMRFC"
     gene            31453..31890
                     /gene="ppdD"
                     /locus_tag="OPV72_000149"
     CDS             31453..31890
                     /gene="ppdD"
                     /locus_tag="OPV72_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase-dependent pilin"
                     /protein_id="HCR9912570.1"
                     /translation="MEKQRGFTLIELMVVIGIIAILSAIGIPAYQNYLRKAALTDMLQ
                     TFVPYRTAVELCALEHGGTSTCDAGVNGIPSPVITRYVSGMSVEKGVITLTGQESLSG
                     LSVIMTPAWDNANGITGWTRNCNIQSDSALQQACEDVFRFDAN"
     gene            31900..33285
                     /gene="gspE"
                     /locus_tag="OPV72_000150"
     CDS             31900..33285
                     /gene="gspE"
                     /locus_tag="OPV72_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspE"
                     /protein_id="HCR9912571.1"
                     /translation="MKDAQLNTLCQRHQAVLINSASNSITVAVVDAPSHALLDALHFA
                     TQKQIDIVCWTRQQMENHRHKPDQAPSTNAAKGGETAAQLLNQTLRSAMAKRASDIHL
                     EPGASRYRIRLRIDGVLHILQDIAKETGLALTARLKVLGNLDIAEHRLPQDGQFTVDL
                     TGDSISFRIATLPCKEGEKVVLRLLHQVEQTLDLDTLGMYGAQLTAFRQALQQPQGLV
                     LVTGPTGSGKTVTLYSALQTRNTPGINLCSVEDPIEIPLDGINQTQIHPRAGLTFQNV
                     LRALLRQDPDIIMVGEIRDGDTAEIAIKAAQTGHLVLSTLHTNSTSETLIRLQQIGVT
                     RWMISSALTLVVAQRLVRKLCPHCKQRLSDPVVLSPNLWPSALPRWQANGCQHCYHGF
                     YGRTALFEVLTVTPALRQLIASGASAQALEAHLQQTGTGTLFENGCRAVEQGMTSFEE
                     ILRVLGMPHER"
     gene            33275..34477
                     /gene="hofC"
                     /locus_tag="OPV72_000151"
     CDS             33275..34477
                     /gene="hofC"
                     /locus_tag="OPV72_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein transport protein HofC"
                     /protein_id="HCR9912572.1"
                     /translation="MSVKQLWRWQGVNDKGQLEQDVVWVDNRLALIITLQHQRIMPLR
                     IKRISVNAALWKEEQSAEIIHQLATLIHAGLTLSEGLELLAKQHPHRQWQALLRTLAH
                     ELEQGVPFSSALVSWPQVFPPLYQTMIRTGELTGKLAECCFELARQQKAQRQITVSVK
                     KALRYPAIILTMAALVVFAMLHFVLPEFAAIYRSFNTPLPLLTRGIIAIAQWGPAWGW
                     LILFLTMLVAIAHRRLKQKPSWQAQRQRLLLRLPVMGRLIRGQKLAQIFTVLALTQSA
                     GIPFLQGLESAIDSLGCPYWSQRLTQVHQEIAAGNPVWLALKNTQEFSPLCLQLVRTG
                     EASGSLDIMLHNLARHHSESTLALADNLASLLEPALLIITGLIIGTLVVAMYLPIFHL
                     GDAMSGMG"
     gene            complement(34508..35551)
                     /locus_tag="OPV72_000152"
     CDS             complement(34508..35551)
                     /locus_tag="OPV72_000152"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008461816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HCR9912573.1"
                     /translation="MRIEEDLKLGFKDVLIRPKRSTLKSRSDVELERQFTFKHSGQTW
                     SGVPIIAANMDTVGTFEMAQALAGFDILTAVHKHYSVEEWAAFINTASADVLKHVMVS
                     TGTSDADFEKTVQILALNPALNFVCIDVANGYSEHFVQFVAKAREAWPSKTICAGNVV
                     TGEMCEELILSGADIVKVGIGPGSVCTTRVKTGVGYPQLSAVIECADAAHGLGGMIVS
                     DGGCTMPGDVAKAFGGGADFVMLGGMLAGHEESGGSVVEENGEKFMLFYGMSSESAMN
                     RHVGGVAKYRAAEGKTVKLPLRGPVGNTARDILGGLRSACTYVGASRLKELTKRTTFI
                     RVQEQENRIFNSL"
     gene            35777..36397
                     /gene="coaE"
                     /locus_tag="OPV72_000153"
     CDS             35777..36397
                     /gene="coaE"
                     /locus_tag="OPV72_000153"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HCR9912574.1"
                     /translation="MRYTVALTGGIGSGKSTVADAFADLGITVIDADIIARQMVEPGQ
                     PALNAIAEHFGSELIAADGTLRRRALRERIFSHPEEKAWLNALLHPLIQQETQRQFQQ
                     ATSPYVLWVVPLLVENRLYQKANRVLVVDVTPETQLIRTMQRDDVTREHVEHILAAQA
                     TREARLAVADDVIDNNGAPDAIASDVARLHASYLKLASQFVSQEKP"
     gene            36397..37140
                     /gene="zapD"
                     /locus_tag="OPV72_000154"
     CDS             36397..37140
                     /gene="zapD"
                     /locus_tag="OPV72_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapD"
                     /protein_id="HCR9912575.1"
                     /translation="MHTQVLFEHPLNEKMRTWLRIEFLIQQLSINLPIADHAGALHFF
                     RNISDLLDVFERGEVRTELLKELERQQRKLQAWVEVPGVDQDRIEALRQQLKSAGSVL
                     ISAPRIGQQLREDRLIALVRQRLSIPGGCCSFDLPTLHIWLHLQQAQRDAQIESWLAS
                     LNPLTQALTLVLDLIRNSAPFRKQTSLNGFYQDNGDDADLLRLMLTLDSQLYPQISGH
                     KSRFAIRFMPLDSENGLVPERLDFELACC"
     gene            37150..37341
                     /gene="yacG"
                     /locus_tag="OPV72_000155"
     CDS             37150..37341
                     /gene="yacG"
                     /locus_tag="OPV72_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase inhibitor YacG"
                     /protein_id="HCR9912576.1"
                     /translation="MSDVTVVNCPTCGKPVVWGEISPFRPFCSKRCQLIDLGEWAAEE
                     KRIASSGDQSDSDDWSEER"
     gene            complement(37338..38279)
                     /locus_tag="OPV72_000156"
     CDS             complement(37338..38279)
                     /locus_tag="OPV72_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001697068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCR9912577.1"
                     /translation="MKAGLIMRHDVMSVLHAFCMIAENHSFTRAAAQLHISTSALSQN
                     MRQLEDELGVKLLNRTTRRVGLTEAGHAFLASIRPALNHIDEAMEHACQSRDIPGGTL
                     RLTVPRTAATLLLQPNLAGFMRDYPDIRLDIDVNDGFVDLINERFDAGIRFGDAVQLD
                     MNVVPLGDVLRPAIVASPAYLARFGTPLHPQELINHRCLCHRFTRESGLYRWEFVHGA
                     QRLEITPEAALMVNDKALRLSAARDGAELTYVFEQDVHEDLQDGRLCSVLEEWLPAAD
                     RFYLYYPGRAHMAPKLRVFIDYFCHKAILPSQQSYHR"
     gene            38365..39354
                     /locus_tag="OPV72_000157"
     CDS             38365..39354
                     /locus_tag="OPV72_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HCR9912578.1"
                     /translation="MQYRTLGANGPRVSAIGLGCMGMSAFYGAHDDSTSIKTLHYALD
                     QGVTLLDTADMYGPYTNERLVGRAIADRRDRVFLATKFGIVLDPANPMARGVNGRPEY
                     VRRSCEQSLQRLGVDHIDLYYQHRVDPSVPIEETVGAMADLVREGKVRYLGLSEASTQ
                     TLERAHNVHPITALQSEYSLWSREAEISALSTCERLGIGFVAYSPLGRGFLTGTIKTP
                     EDFAANDFRRTNPRFMGENFSRNLRLAEAIKQMAREKECTPAQLALAWLLARNRHLVP
                     IPGTRHCARVDENLGALSLTLSPQELAAIEAVFPHDAAAGPRYWPEIMSTLNR"
     gene            complement(39388..39783)
                     /gene="mutT"
                     /locus_tag="OPV72_000158"
     CDS             complement(39388..39783)
                     /gene="mutT"
                     /locus_tag="OPV72_000158"
                     /EC_number="3.6.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000736055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase MutT"
                     /protein_id="HCR9912579.1"
                     /translation="MKKLQIAVGIIRNPNDEIFITRRAADAHMANKLEFPGGKIEAGE
                     TPEQALIRELQEEVGITPTQVTLFDTLEYQFPDRHITLWFWLVERWEGEPWGKEGQPG
                     RWIAQNALNTDDFPPANEPIIRKLRQFAP"
     gene            complement(39939..42644)
                     /gene="secA"
                     /locus_tag="OPV72_000159"
     CDS             complement(39939..42644)
                     /gene="secA"
                     /locus_tag="OPV72_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HCR9912580.1"
                     /translation="MLIKLLTKVFGSRNDRTLRRMRKAVSLINAMEPEMEKLSDDELK
                     AKTNEFRARIGKGESVESLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNDRCIAEM
                     RTGEGKTLTATLPAYLNALSGKGVHVVTVNDYLAQRDAENNRPLFEFLGMSVGINLPG
                     MPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDE
                     ARTPLIISGPAEDSSEMYKKVNKIIPHLIRQEKEDSDTFQGEGHFSVDEKARQVNLTE
                     RGLVLIEELLVQEGIMDEGESLYSPGNIMLMHHVTAALRAHALFTRDVDYIVKDGEVI
                     IVDEHTGRTMQGRRWSDGLHQAVEAKEGVEIQNENQTLASITFQNYFRLYEKLAGMTG
                     TADTEAFEFSSIYKLDTVVVPTNRPMIRKDLPDLVYITEAEKIQAIIEDIKERTANGQ
                     PVLVGTISIEKSEVVSRELTKAGIKHNVLNAKFHANEAGIVAQAGYPAAVTIATNMAG
                     RGTDIMLGGSWQAEVAALEAPTEEQIAQIKADWQVRHDAVLAAGGLHIIGTERHESRR
                     IDNQLRGRSGRQGDPGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVT
                     KAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYTQRNELLDVSDVSDTINSIRED
                     VFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLEMPIAEWLDKEPELHEETLRERIL
                     AQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKD
                     PKQEYKRESFAMFAAMLESLKYEVISTLSKVQVRMPEEVEAMEMQRREEAERLAQMQQ
                     LSHQDDDAAVAADLAAQTGERKIGRNDPCPCGSGKKYKQCHGRLS"
     gene            complement(42706..43203)
                     /gene="secM"
                     /locus_tag="OPV72_000160"
     CDS             complement(42706..43203)
                     /gene="secM"
                     /locus_tag="OPV72_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308128.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="secA regulator SecM"
                     /protein_id="HCR9912581.1"
                     /translation="MSGILTRWRQLGRRYFWPHLLLGMVAASFGLPALSNAAETNTPA
                     RTTASTASKVNFSHLALLEASNRRPNFTVDYWHQHAIRTVIRHLSFAMAPQTLPVADA
                     PSPLQAHHIALLNTLSAMLTQEGTPPAIVRRLSLAYFAPQTAFSIPAWISQAQGIRAG
                     PQRLS"
     gene            complement(43485..44402)
                     /gene="lpxC"
                     /locus_tag="OPV72_000161"
     CDS             complement(43485..44402)
                     /gene="lpxC"
                     /locus_tag="OPV72_000161"
                     /EC_number="3.5.1.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-3-O-acyl-N-acetylglucosamine deacetylase"
                     /protein_id="HCR9912582.1"
                     /translation="MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDL
                     NPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIP
                     IMDGSAAPFVYLLLDAGIDALNCAKKFVRIKETVRVEDGDKWAEFRPYNGFTLDFTID
                     FNHPAIDSSSQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVV
                     DDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVL
                     AKQEAWEFVTFQDDAELPLAFKAPSTVLA"
     gene            complement(44503..45654)
                     /gene="ftsZ"
                     /locus_tag="OPV72_000162"
     CDS             complement(44503..45654)
                     /gene="ftsZ"
                     /locus_tag="OPV72_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015965916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HCR9912583.1"
                     /translation="MFEPMELTNDAVITVIGVGGGGGNAVEHMVRERIEGVEFFAVNT
                     DAQALRKTAVGQTIQIGSGITKGLGAGANPEVGRNAADEDREALRAALEGADMVFIAA
                     GMGGGTGTGAAPVVAEVAKDLGILTVAVVTKPFNFEGKKRMAFAEQGITELSKHVDSL
                     ITIPNDKLLKVLGRGISLLDAFGAANDVLKGAVQGIAELITRPGLMNVDFADVRTVMS
                     EMGYAMMGSGVASGEDRAEEAAEMAISSPLLEDIDLSGARGVLVNITAGFDLRLDEFE
                     TVGNTIRAFASDNATVVIGTSLDPDMNDELRVTVVATGIGMDKRPEITLVTNKQVQQP
                     VLDRYQQHGMAPLTQEQKTVAKVVNDNAPQAAKEPDYLDIPAFLRKQAD"
     gene            complement(45715..46977)
                     /gene="ftsA"
                     /locus_tag="OPV72_000163"
     CDS             complement(45715..46977)
                     /gene="ftsA"
                     /locus_tag="OPV72_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HCR9912584.1"
                     /translation="MIKATDRKLVVGLEIGTAKVAALVGEVLPDGMVNIIGVGSCPSR
                     GMDKGGVNDLESVVKCVQRAIDQAELMADCQISSVYLALSGKHISCQNEIGMVPISEE
                     EVTQEDVENVVHTAKSVRVRDEHRVLHVIPQEYAIDYQEGIKNPVGLSGVRMQAKVHL
                     ITCHNDMAKNIVKAVERCGLKVDQLIFAGLAASYSVLTEDERELGVCVVDIGGGTMDI
                     AVYTGGALRHTKVIPYAGNVVTSDIAYAFGTPPSDAEAIKVRHGCALGSIVGKDESVE
                     VPSVGGRPPRSLQRQTLAEVIEPRYTELLNLVNEEILQLQEQLRQQGVKHHLAAGIVL
                     TGGAAQIEGLAACAQRVFHTQVRIGAPLNITGLTDYAQEPYYSTAVGLLHYGKESHLN
                     GEAEVEKRVTASVGSWIKRLNSWLRKEF"
     gene            complement(46974..47804)
                     /gene="ftsQ"
                     /locus_tag="OPV72_000164"
     CDS             complement(46974..47804)
                     /gene="ftsQ"
                     /locus_tag="OPV72_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ"
                     /protein_id="HCR9912585.1"
                     /translation="MSQAALNTRNSDEETPSSRRNNGTRLAGILFLLTVLCTVFVSGW
                     VVLGWMEDAQRLPLSKLVLTGERHYTRNDDIRQAILALGAPGTFMTQDVNIIQSQIER
                     LPWIKQASVRKQWPDELKIHLVEYVPIARWNDQHMVDAEGNTFSVPSDRIGKQVLPML
                     YGPEGSASEVLQGYREMGQVLAKDKFTLKEAAMTARRSWQLTLNNGIKLNLGRGDTMK
                     RLARFVELYPVLQQQAQTDGKRISYVDLRYDSGAAVGWAPLPPEESNQQQNQAQAEQQ
                     "
     gene            complement(47806..48726)
                     /locus_tag="OPV72_000165"
     CDS             complement(47806..48726)
                     /locus_tag="OPV72_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HCR9912586.1"
                     /translation="MADKIAVLLGGTSAERDVSLNSGAAVLAGLREGGIDAHPVDPQE
                     VDVAQLKAMGFQKVFIALHGRGGEDGTLQGMLELLGLPYTGSGVMASALSMDKLRSKL
                     LWQGAGLPVAPWVALTRAEFEKGLSEEQKARISALGLPLIVKPSREGSSVGMTKVVEE
                     NALQGALSLAFQHDDEILIEKWLCGPEFTVAIVGEEILPSIRIQPAGTFYDYEAKYLS
                     DETQYFCPAGLEASQEAALQSLVLQAWKALGCTGWGRIDVMLDSDGQFYLLEANTSPG
                     MTSHSLVPMAARQAGMSFSQLVVRILELAD"
     gene            complement(48719..50194)
                     /gene="murC"
                     /locus_tag="OPV72_000166"
     CDS             complement(48719..50194)
                     /gene="murC"
                     /locus_tag="OPV72_000166"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HCR9912587.1"
                     /translation="MNTQQLAKLRSIVPEMRRVRHIHFVGIGGAGMGGIAEVLANEGY
                     QISGSDLAPNPVTQQLTSLGATIFFNHRPENVRDASVVVVSSAISADNPEIVAAHEAR
                     IPVIRRAEMLAELMRFRHGIAIAGTHGKTTTTAMVSSIYAEAGLDPTFVNGGLVKAAG
                     VHARLGHSRYLIAEADESDASFLHLQPMVAIVTNIEADHMDTYHGDFENLKQTFINFL
                     HNLPFYGRAVMCVDDPVIRELLPRVGRQTTTYGFSEDADVRVEDYQQIGPQGHFTLLR
                     QGMPDLHVTLNAPGRHNALNAAAAVAVATEEGIDDDAILRALESFQGTGRRFDFLGEF
                     PLEPVNGKAGTAMLVDDYGHHPTEVDATIKAARAGWPDKNLVMLFQPHRYTRTRDLYD
                     DFANVLTQVDALLMLDVYPAGEAPIPGADSRSLCRTIRNRGKIDPILVSDPAQVATML
                     APVLTGNDLILVQGAGNVGKIARYLSEIKLKPQIQEEEQHG"
     gene            complement(50313..51380)
                     /gene="murG"
                     /locus_tag="OPV72_000167"
     CDS             complement(50313..51380)
                     /gene="murG"
                     /locus_tag="OPV72_000167"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HCR9912588.1"
                     /translation="MSGQPKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTSDR
                     MEADLVPKHGIDIDFIRISGLRGKGVKALLAAPLRIFNAWRQARAIMKRFKPDVVLGM
                     GGYVSGPGGLAAWSLGIPVVLHEQNGIAGLTNQWLAKIATTVMQAFPGAFPNAEVVGN
                     PVRTDVLALPLPQVRLAGRDGPIRVLVVGGSQGARVLNQTMPQVAARLGDTVTIWHQS
                     GKGAQLTVEQAYAGAGQPQHKVTEFIDGMAAAYAWADVVVCRSGALTVSEIAAAGLPA
                     IFVPFQHKDRQQYWNALPLENAGAAKIFEQPQFTVEAVADTLAGWSREALLTMAERAR
                     AVSIPDATERVASEVSRVART"
     gene            complement(51377..52621)
                     /gene="ftsW"
                     /locus_tag="OPV72_000168"
     CDS             complement(51377..52621)
                     /gene="ftsW"
                     /locus_tag="OPV72_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsW"
                     /protein_id="HCR9912589.1"
                     /translation="MRLSLPRLRMPRVPGFGLLAWLFAALKGWVMASRDKDADSLIMY
                     DRTLLWLTFGLAAIGFVMVTSASMPVGQRLANDPFLFAKRDALYIFLAFCLAMVTLRL
                     PMTFWQKYSTTMLIASIIMLLIVLVVGSSVNGASRWIALGPLRIQPAEFTKLSLFCYL
                     ANYLVRKVDEVRNNLRGFLKPMGVILVLAVLLLAQPDLGTVVVLFVTTLAMLFLAGAK
                     LWQFIAIIGMGISAVILLILAEPYRIRRVTSFWNPWEDPFGSGYQLTQSLMAFGRGEI
                     WGQGLGNSVQKLEYLPEAHTDFIFAIIGEELGYIGVVLALLMVFFVAFRAMSIGRKAL
                     EIDHRFSGFLACSIGIWFSFQALVNVGAAAGMLPTKGLTLPLISYGGSSLLIMSTAIM
                     FLLRIDYETRLEKAQAFTRGSR"
     gene            complement(52621..53937)
                     /gene="murD"
                     /locus_tag="OPV72_000169"
     CDS             complement(52621..53937)
                     /gene="murD"
                     /locus_tag="OPV72_000169"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HCR9912590.1"
                     /translation="MADYQDKNVVIIGLGLTGLSCVDFFLARGVTPRVMDTRVTPPGL
                     DKLPQEVERHVGGLNDEWLLAADLIVASPGIALAHPSLSAAASAGVEIVGDIELFCRE
                     AQAPIVAITGSNGKSTVTTLVGEMAKAAGVNVGVGGNIGLPALMLLDADRELYVLELS
                     SFQLETTSSLQAAAATVLNVTEDHMDRYPFGLQQYRAAKLRVYEKAKVCVVNADDALT
                     MPVRGADERCVSFGVNMGDYHLNRQQGETWLRVKGEKVLNVKEMKLSGQHNYTNALAA
                     LALADAVGLPRASSLKALTTFTGLAHRFQLALEHNGVRWINDSKATNVGSTEAALNGL
                     HVDGTLHLLLGGDGKSADFSPLARYLTGDRIRLYCFGRDGAQLAALRPEIAQQTETME
                     EAMRLLAPHVQPGDMVLLSPACASLDQFKNFEQRGDVFTRLAKELG"
     gene            complement(53940..55022)
                     /gene="mraY"
                     /locus_tag="OPV72_000170"
     CDS             complement(53940..55022)
                     /gene="mraY"
                     /locus_tag="OPV72_000170"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HCR9912591.1"
                     /translation="MLVWLAEHLVKYYSGFNVFSYLTFRAIVSLLTALFISLWMGPRM
                     IARLQKLSFGQVVRNDGPESHFSKRGTPTMGGIMILTAIVISVLLWAYPSNPYVWCVL
                     VVLIGYGIIGFVDDYRKVVRKDTKGLIARWKYFWMSVIALGVAFALYLVGKDTPATQL
                     VVPFFKDVMPQLGLFYILLSYFVIVGTGNAVNLTDGLDGLAIMPTVFVAAGFALVAWA
                     TGNMNFANYLHIPYLRHAGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGA
                     LGIIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWP
                     EPRVIVRFWIISLMLVLIGLATLKVR"
     gene            complement(55016..56374)
                     /gene="murF"
                     /locus_tag="OPV72_000171"
     CDS             complement(55016..56374)
                     /gene="murF"
                     /locus_tag="OPV72_000171"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HCR9912592.1"
                     /translation="MISVTLSKIADVLGAEHRGADLTLDTVITDTRKVTPGCLFVALK
                     GERFDAHDFADKAKANGAGALLVSRPLDIDLPQVIVKDTRQAFGQLAAWVRMQVPARV
                     VALTGSSGKTSVKEMTAAILSQCGNTLYTASNFNNDIGVPITLLRLNHDYDYAVIELG
                     ANHQGEIAWTVSLTRPEAALVNNLAAAHLEGFGSLAGVAKAKGEIYTGLPENGIAIMN
                     ADNNDWLNWQSIIGDRQVWRFSPNAANSDFTAANIHVTSHGTEFTLQTPMGSIDVLLP
                     LPGRHNIANALAAAALSMAVGATLAAVKAGLAALKAVPGRLFPIQLSENQLVLDDAYN
                     ANVGSMTAAVQVLSEMPGYRVLVVGDMAELGAESEACHLQVGEAAKAAGIDRVLSTGK
                     LSQVISHASGVGEHFADKAALIARLHALLQEQPMMTILVKGSRSAAMEDVVHALQEKG
                     SC"
     gene            complement(56371..57858)
                     /gene="murE"
                     /locus_tag="OPV72_000172"
     CDS             complement(56371..57858)
                     /gene="murE"
                     /locus_tag="OPV72_000172"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HCR9912593.1"
                     /translation="MADRNLRDLLAPWVAGLPARELREMTLDSRVAAAGDLFVAVVGH
                     QADGRRYIPQAIAQGVAAIIAEAKDEASDGEIREMHGVPVVYLSQLNERLSALAGRFY
                     HEPSENMRLVAVTGTNGKTTTTQLLAQWSQLLGETSAVMGTVGNGLLGKVIPTENTTG
                     SAVDVQHVLASLVAQGATFGAMEVSSHGLVQHRVAALKFAASVFTNLSRDHLDYHGDM
                     AHYEAAKWMLYSTHHHGQAIVNADDEVGRRWLASLPDAVAVSMEGHINPNCHGRWLKA
                     EAVEYHDRGVTIRFASSWGEGEIESCLMGAFNVSNLLLALATLLALGYPLTDLLKTAA
                     RLQPVCGRMEVFTAPGKPTVVVDYAHTPDALEKALQAARLHCAGKLWCVFGCGGDRDK
                     GKRPLMGAIAEEFADIVVVTDDNPRTEEPRAIINDILAGMLDAGQVRVMEGRAEAVTN
                     AIMQAKDNDVVLIAGKGHEDYQIVGTQRLDYSDRVTAARLLGVIA"
     gene            complement(57845..59611)
                     /gene="ftsI"
                     /locus_tag="OPV72_000173"
     CDS             complement(57845..59611)
                     /gene="ftsI"
                     /locus_tag="OPV72_000173"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase FtsI"
                     /protein_id="HCR9912594.1"
                     /translation="MKAAAKTQKSKRQEEQTNFISWRFALLCGCILLALVFLLGRAAW
                     LQIIAPDMLVRQGDMRSLRVQEVSTSRGMITDRSGRPLAVSVPVKAIWADPKEVHDAG
                     GISVGDRWKALSTALNIPLDQLSARINANPKGRFIYLARQVNPDMADYIKKLKLPGIH
                     LREESRRYYPSGEVTAHLIGFTNVDSQGIEGVEKSFDKWLTGQPGERIVRKDRYGRVI
                     EDISSTDSQAAHNLALSIDERLQALVYRELNNAVAFNKAESGSAVLVDVNTGEVLAMA
                     NSPSYNPNNLAGTPKDAMRNRTITDVFEPGSTVKPMVVMTALQRGIVNENTVLNTVPY
                     RINGHEIKDVARYSELTLTGVLQKSSNVGVSKLALAMPSSALVDTYSRFGLGKATNLG
                     LVGERSGLYPQKQRWSDIERATFSFGYGLMVTPLQLARVYATIGSYGIYRPLSITKVD
                     PPVPGERIFPESTVRTVVHMMESVALPGGGGVKAAIKGYRIAIKTGTAKKVGPDGRYI
                     NKYIAYTAGVAPASQPRFALVVVINDPQAGKYYGGAVSAPVFGAIMGGVLRTMNIEPD
                     ALATGEKNEFVINQGEGTGGRS"
     gene            complement(59627..59992)
                     /gene="ftsL"
                     /locus_tag="OPV72_000174"
     CDS             complement(59627..59992)
                     /gene="ftsL"
                     /locus_tag="OPV72_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000625658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HCR9912595.1"
                     /translation="MISRVTEALSKVKGSIGSNERHALPGVIGDDLLRFGKLPLCLFI
                     CIILTAVTVVTTAHHTRLLTAQREQLVLERDALDIEWRNLILEENALGDHSRVERIAT
                     EKLQMQHVDPSQENIVVQK"
     gene            complement(59989..60930)
                     /gene="rsmH"
                     /locus_tag="OPV72_000175"
     CDS             complement(59989..60930)
                     /gene="rsmH"
                     /locus_tag="OPV72_000175"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HCR9912596.1"
                     /translation="MMENFKHTTVLLDEAVNGLNIRPDGIYIDGTFGRGGHSRLILSQ
                     LGEEGRLLAIDRDPQAIAVAQTINDPRFSIIHGPFSALADYVAERELTGKIDGILLDL
                     GVSSPQLDDAERGFSFMRDGPLDMRMDPTRGQSAAEWLQTAEEADIAWVLKTFGEERF
                     AKRIAHAIVERNREQPMTRTKELAEVVAAATPVKDKFKHPATRTFQAVRIWVNSELEE
                     IEQALKSSLSVLASGGRLSIISFHSLEDRIVKRFMREQSRGPQVPAGLPMTEAQLKKL
                     GGRELRALGKLMPGEKEVAENPRARSSVLRIAERTNA"
     gene            complement(60932..61390)
                     /gene="mraZ"
                     /locus_tag="OPV72_000176"
     CDS             complement(60932..61390)
                     /gene="mraZ"
                     /locus_tag="OPV72_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020325403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HCR9912597.1"
                     /translation="MFRGATLVNLDSKGRLTVPTRYREQLIESATGQIVCTIDIHHPC
                     LLLYPLPEWEIIEQKLSRLSSMNPVERRVQRLLLGHASECQMDGAGRLLIAPVLRQHA
                     GLTKEVMLVGQFNKFELWDETTWYQQVKEDIDAEQSATETLSERLQDLSL"
BASE COUNT        14134 a        17879 c        15803 g        14001 t
ORIGIN      
        1 gccctctttg cagcactttg cgggctgtat cttcttatcg gaggtgtctg gctggttgct
       61 attggcggtt cctggtacta ccccatcgcg ggcctcgtga tgctggttgt ggccggattg
      121 ctatggcgca gtaaacgtgc cgcactgtgg ctgtatgccg ccctgctgct ggcgacaatg
      181 atttggggcg tgtgggaagt cgggttcgac ttctgggcac tcacgccgcg tagcgatatc
      241 ctggtgtttt tcggcatctg gctaatattg ccgtttgtct ggcatcggct ggtggttcct
      301 tccagcggcg cagtggcggc gctggtcgtg gcgctgctga ttagcggcgg cattctgacc
      361 tgggctggct tcaacgaccc gcaggagatc aacggtacgc ttcgcgccga cgccacgccc
      421 gccgcaacaa gttcgtcgat cgccgacgaa gactggccgg cctatggacg taatcaggaa
      481 ggccaacgct attcgccgct gaaacagatc actgcggata acgttcacca actgaaagaa
      541 gcgtgggtct tccgcaccgg cgatctgaaa caacccaacg atccgggtga aatcaccaac
      601 gaagtgaccc cgataaaagt cggtgatacg ctttatctgt gtacagctca ccagcgtctg
      661 ttcgcgctgg acgccgccag cggtaaagag aagtggcatt ttgatcctca gttgaagacc
      721 gattcgtctt tccagcatgt gacctgccgc ggcgtctctt atcatgaggc caaagcggat
      781 accgcctcgc cggaggtcat cgccgactgt ccgagccgca ttatcctccc ggtcaacgac
      841 ggtcgccttt tcgcggtgaa tgccgaaacc ggcaagctgt gtgaaacctt cgccaacaaa
      901 ggcgtcctga atctgcaaac caatatgccg gataccacgc cgggactgta tgaaccgacg
      961 tcgccgccga ttatcaccga taaaacaatt gtcattgccg gttcggtcac ggataacttc
     1021 tctactcgcg aaacgtccgg cgttatccgt ggttttgatg ttaatagcgg taaactactg
     1081 tgggccttcg atcctggggc gaaagatccg aacacgattc cagccgatga gcacgctttt
     1141 acctttaact cgccgaactc ctgggcccct gccgcctatg atgcgaaact ggatctggtc
     1201 tatctgccga tgggcgtgac cacgccggat atctggggcg gtaaccgcac gccggagcag
     1261 gaacgttatg ccagctccat cctggcgctg aatgccacca ccgggaaact ggcctggagt
     1321 tatcagaccg tccatcacga tctgtgggat atggacctgc cggcacagcc gacgctggcg
     1381 gatattaccg ttgacggtac taccgttccg gttatctatg caccagcgaa aaccggtaat
     1441 atctttgtgc tggacagacg taatggcgag ctggtcgtgc ccgctccgga aaaaccggtc
     1501 ccgcagggcg cggcaaaagg cgattatgtc gccaaaactc agccgttctc tgatttaacc
     1561 ttccgcccga aaaaagatct ctccggcgcg gatatgtggg gcgcgaccat gttcgaccaa
     1621 ctggtgtgcc gcgttatgtt ccaccagttg cgctatgaag gtatcttcac cccgccatcc
     1681 gagcagggga cattggtatt ccctggcaac ctggggatgt ttgaatgggg cggtatttcc
     1741 gtcgatccag accgtcaggt cgctatcgct aacccgatgg cgctgccgtt tgtctcgaag
     1801 ctgatcccac gcggcccggg taatccaatg gaaccgccga aagacgcgaa aggtaccggt
     1861 acagaagcgg gtattcagcc gcagtacggc gtaccgttcg gcgtcacgct gaatccgttc
     1921 ctttcgccgt ttggtttgcc gtgtaaacaa ccggcctggg gctacatttc cgcgttggat
     1981 ctgaagacca atgaaatcgt gtggaagaaa cgtataggga cgccgcgcga cagtatgccg
     2041 ttcccgatgc cggttccggt gccgttcaac atggggatgc ccatgctggg cgggccaatc
     2101 tcaaccgccg gtaacgtgct gttcattgcc gcgaccgccg acaactacct gcgcgcttat
     2161 aacatgagca acggggaaaa actgtggcag ggacgtttac ccgccggagg ccaggcaacg
     2221 ccgatgacct atgaggtaaa cggtaagcag tacgtggtca tttctgccgg aggccacggt
     2281 tcgtttggta cgaagatggg cgactatatc gtggcctatg ctttgcctga cgacgcgaaa
     2341 taaccattaa tgcccggcgt atgccgggca ttgtgccggg tagcggtttc gccttacccg
     2401 gcctgcgtca cagacatcga ttagaccgta aatcctaaca tcattcccgt atcttcatgt
     2461 tctaacagat gacagtgcgc catataggca tgttccttcg gcgcgtcgtg atcgaacttg
     2521 accagcactt cgctgatacc gccctcaacg cgtaccgtat ccttccagcc cgttctgtgc
     2581 gccgctggcg ctttgccgtt ctctgacaaa atacggaact gggtgccgtg aatatggaaa
     2641 ggatgcagca tcatgtcacc cacgccggaa atcacccaac gttcatgtcg gcctttttgc
     2701 gccgcgaaca tcggtttgtt catatcgaag acctggccgt tgataaagtt agcgttatgg
     2761 aagtcgaatt ttccgccgtg attcatattg cccatcgcgc catgattcat cccgctgtga
     2821 tccatgttgc catgatccat ctcgccatgc cccatattgc cgccctgcat atgcgcgttc
     2881 atgctgtcat gatccatgcc gctcatcgcc tgagcgccat atttcttcat cagcatttgc
     2941 atccccatca tatcaaggcg cgggtccatc gacagtttca ggttgcgcac cgtcagccct
     3001 tccagcgacg gcagcgccgg catcgtcgtc aacgtatccg gcagcgtacc ggaggcggta
     3061 atccgcagcg gctggatacg catcaccgga tgcggtttat caaacggagc gatcgccatt
     3121 cccatctggc tgaccggcag ggtcaccaga tcaaaggctt tcccgtcgct gatatccacc
     3181 agcacttcaa aacgctcgcc cattaataac ggcagttcgg tgactttcac cggctccgcc
     3241 agcaggccgc cgtcgctggc gatcacataa agcggacgat tatcgctggc ggcgatattc
     3301 agcgaacgcg cattacagcc attcagcaag cgcagacgta gccagccttt cggcgcggaa
     3361 tgctgcggat agatagcgcc attggtcagc agcgtatcgc caaaccagcc gacggcggcg
     3421 gtcataatat ccagttgata atcaatctgg ccatcggcgg agaagcgttt gtcctgaatg
     3481 atcaccggca catcgtcgat accccactgt ttcggcaggc gcaatttgcg aatctcgtca
     3541 tcttcaatca gcaccagtcc ggcgaggccc atcgccacct ggcgcccggt tttgccgtgt
     3601 ttgtgcggat gaatccagca ggtcgcggcg cgttgctgcg gcgtaaacgt caccgtgcgg
     3661 gttccgccag cgggaataat cccctgcggg ccgccgtcaa cgatgcccgg aatctccaga
     3721 ccatgccagt gaagcgtcgt gtcttcggcc agttggttat ggatatcaac ggtcacgctt
     3781 tttcctttgt gaagctgtac cgctggcccc agcaaattac cgttgtagcc ccaggttgtc
     3841 gcgttcttac cggcgaatgt cgactgtccg gctttaacaa ttaactgcat acggttgctc
     3901 gcatctgccg ttaacaggtc aggaataggc aacgcgggac gttcggcggc aaaagcggcg
     3961 cggctccaca gcggcagcgc tgatgcaacc cccagcgcca ctgaatattt taagaaatca
     4021 cggcgtaaca taatcatttc cttataatga acaggcgggt gtctaagctt agaccctgcc
     4081 ctaacgggaa ggtcaagcca gcaacacgtc tttaccgttc ctgacagcaa tacaacaaga
     4141 atgaaaacgc cgcgaccaat cctgataata aaagtcgtcg ctacgttctc agtatgctaa
     4201 cgttgacttt ccctgatgcc gtggtagaag caatgaagac gtttttcaga cccgtgttgt
     4261 ttggcagcct gatggcctta tgcgcaaata gctatgcgct tactgaatcc gaagctgaag
     4321 atatggccga tttaacggcg gttttcgttt ttctgaaaaa tgactgtggt taccaaaatt
     4381 tacccaacag tcagattcgc cgtgcgctgg tcttttttgc ccagcaaaat cagtgggacc
     4441 tgagtaacta cgacaccttc gatatgaaat cgttgggcga agacagctac cgcgatctta
     4501 gcggcatcgg tattccggtc gctaaaaaat gcaaagctct ggcccgcgat tctctgagcc
     4561 tgttagccta cgttaaataa tcctccgcga tcctattgct gaaataatga ccgtgcatcc
     4621 acggtcattg ttagctatga tgttgcgccc tttttttacg ggtgttaaca atggaggtat
     4681 cagccaatgg ccgaaaatac gatgtggcat gaaacgctac acgaccagtt tggtcagtac
     4741 tttgccgtag acaacgttct gtatcatgaa aaaaccgatc accaggattt aatcatcttt
     4801 gaaaacgccg cttttggccg cgtgatggcg ctggacggcg tggtacagac caccgaacgc
     4861 gacgagttta tttatcatga aatgatgacc catgtcccgc tgctggcgca cggtcatgcg
     4921 aaacacgttc tgattatcgg cggcggcgac ggcgcaatgc tacgtgaagt tacccggcat
     4981 aaaaacgtcg aaaccatcac catggtagag atagacgctg gcgtagtctc gttttgccgc
     5041 cagtatttac ccaaccacaa tgccggcagc tacgacgatc cgcgctttac gctggtgatc
     5101 gacgacggcg tgaatttcgt caatcagacc catcagacct ttgatgtgat catttccgac
     5161 tgtaccgatc cgataggccc cggcgaaagc ctgtttaccc ccgcctttta tgaaggctgt
     5221 aagcgttgcc tgaatccggg cggcattttt gtcgcccaga acggcgtgtg cttcctgcaa
     5281 caggatgaag cgctcgacag ccaccgcaag ctgagtcatt acttcagcga tgtcggcttc
     5341 taccaggcgg cgattccgac ctattacggc ggcattatga ccttcgcctg ggcgacggac
     5401 aacgacgctc ttcgccacct gtcgagcgaa attattcagg cgcgttttca tgccgccggc
     5461 ctcaaatgcc gctattacaa ctcggctatt catgccgctg catttgcgct accgcaatat
     5521 ctacatgacg cactgtccgc acagtgacgt taaggaggtg ataaaaattg aaaaagctga
     5581 aactgcatgg ctttaacaat ctgacgaaaa gcctgagttt ttgtatttac gatatctgct
     5641 acgccaaaac cgcagaagag cgcgatggct atatcgccta tatcgatgaa ctctataacg
     5701 ccaaccgact gaccgagatc ctgtcggaga cctgctccat tatcggcgcg aacatcctga
     5761 acatcgcccg tcaggattat gaaccccagg gcgccagcgt cacgattctg gtgagcgaag
     5821 agccgatcga cccgaaactt atcgaccaaa ccgaacatcc cggcccgctg ccggaaaccg
     5881 tggtggcgca cctcgataag agccatatct gtgtgcatac ctatccggaa agccatccgg
     5941 aaggcgggct ttgcaccttt cgcgccgaca tcgaagtgtc aacctgcggg gtgatttcac
     6001 cgctaaaagc gctcaattac ctgatccacc agctagagtc tgatatcgtc accatcgatt
     6061 accgcgtgcg cggctttacg cgcgacgtca acggtatgaa acactttatc gatcatgaga
     6121 ttaattccat tcagaatttt atgtcggaag atatgaagtc gctgtatgac atggtggatg
     6181 taaacgtgta tcaggaaaat attttccata ccaagatgct gcttaaagag ttcgatctta
     6241 agcactatat gtttcacacc aaaccggaag atctcactga aaccgaacgc cagcagatca
     6301 ccgccgcgct gtggaaagag atgcgcgaga tttactacgg ccgcaatatt tctgcggtct
     6361 gattcaccac tggcagcgcc tgacggcgct gtcactccgg ctgcaccagc gttagcgcaa
     6421 aagcgcgccc ttttagttca acctgcgctg acggcggcag attgacgtcg gtaatcacat
     6481 cattaaagcg ctcaagcggc accacattaa agagcgaatg cgcgccgtac ttactgctgt
     6541 ccgccagcaa cactttgcgc tgcgcattag caataatctc ctgtttaagc ccggccttat
     6601 cttccgttgg ggtcgtcacg cccgttttta ccccccatga attacagctc ataaacgcga
     6661 tgttcggata aacgctgcgc aacagcttgc gcccatgctc accgatacag gactgactgc
     6721 tgtcatcgat acgaccgccg acaatcgtca cttcaatttg ccggaactca gctaaaaaca
     6781 gcgcaatatg cagatcgacg gtgatgaccc gcagcggaag atgggttaag catttcgcca
     6841 gttccatcat tgtcgtaccg gcatccagca cgacggcatc gccagcattg accagcgatg
     6901 cggcaacgcg tgcaatcgcc cgtttttcag cgggcgatcg cagttgtttt tcattggtgg
     6961 tgggctgggc gggttcaaaa cgccgcagcg ccacgccgcc atgactacgg ctgatcacgc
     7021 cctgctcatc cagcttgatc aaatcgcgac ggatagtggc tggcgatgcg tcaaccgcct
     7081 caaccagctg ttctaccgta accagcgtat ggtttttcag atacgccaca atgagatcca
     7141 gacggtgttg tcctttcata acagggaatt atgccagttg cattgccagt ttgatcgata
     7201 cggccatgct ctcagatttt gcttttcccg tccaggcgat atcaaatgcg gtgccatgat
     7261 cggcagaggt ccggataaac ggcagccctg cggtgatatt cacgccatca taaaagccaa
     7321 gcaatttcaa cgggatatgc ccctggtcat gatacatcgc caccaccata tcatactgtc
     7381 cctcataagc ctggagaaat acagtatccg gcgggcacgg cccataaacg tccatacctt
     7441 ttgcgcgggc atcggtaatg gctggcgtca ggatacgcgt ctcttcatcg ccaaacagac
     7501 cattctcgcc cgcatgagga ttcacgcctg ccacggcgat acgcggttta acgtaaccca
     7561 cacgcttgag gaaagtatca gcaataccaa tcaccgtttc gacacgcgtg gtacttaacg
     7621 tatcaaggaa tttacgcagc gcgatatgcg ttgaaacgtg aatcactttt agtttatcgg
     7681 tgtaaagtac catcgcgtaa tcgcggctat gggtcagagt cgcgagcagc tcggtatggc
     7741 ccggatagtt gtgccccgcc aggtgcagcg cctctttatt cagcggcgcg gtagcgatag
     7801 cctgtacgtc gccccgtaac gctaactcgg tggcgcgctt cacgcagcga tacgctaaat
     7861 cccccgcctg cgcctgaact ttcccggcct ccagcgcctc cggctgcgcc agcggctcat
     7921 caatcacatg aatgatgccg ggcgcaaaac gcgcttcggc gacccgttca atggcccgta
     7981 actcgacgtt cggcgtgatg cccttcgcct gtaaacattt caaggttgcg aggcatccaa
     8041 tcaccaccag cggcgcgccg ttgagaccgt cttcacttag cgctttaaca ataatttccg
     8101 gcccaatgcc cgctggatcg cccatggtaa tggcaacggt tttagtctcc acaatacatc
     8161 tcctcaatat aataaagcgc gtcacacaac gtactgtctg aaccgaatcc gcccgctttg
     8221 gtaatgaccg gcagatcgtc aatttcgctg tttacaaacg ttccacaggg aatacagggc
     8281 gccacctcgc tctgaatgcg ataaccttca gcgccaagcg cgccggcgac ggcggtagcg
     8341 atatcgccgc cggtcagaaa cagcccgcca atccgcgcct gctcgataat atttaacgtg
     8401 acgacgccaa gccgatgact cagtcgctcg cccaattgct gacggctcat cgcggatttt
     8461 tcgcacagcg cgtcgattaa ctgtcgatct tctgcgcgac ggctggtgcg taaaatcgta
     8521 tgtcgatgct gacttaacag cgcgcaggcc tgctctacga cagacgcgat ttcctgctcc
     8581 gcgctatccg acaccatgcg cgcggcatcg atatccacga cctccgcacg tccccggcac
     8641 agcgcattat ccacctgacg tcgcgtggct tcgctcatcg aaccggctac caccagtacc
     8701 ggtagccgct gccggtcttg cataaaaagt tcaaccggca acgcattcgc cagaccagct
     8761 gcgccgacga gcagcggcat cgacggttgt tcgcacgccg cttgcgcaat caacgtcagg
     8821 tcccgctctt ctaccgcatc cacgacgata atcccttcgc cctcagccgc ataagccgta
     8881 agtaaggcgc ttaacccgcc gcgtcggaca tcctgtaaaa agacttcata cacagggatc
     8941 tcactttgca acgccactat ctcggcaata cgggaagaga caatgggcgt tttcggatcg
     9001 ctagcaaatt cggtttccag tagcggggcg ccattaacca gacattttcc ttcaagcgtc
     9061 gtgcgtccgg ccgcagggat cgcagcagcg ataacggcca gttttcgctg actggcgcgc
     9121 atagctgccg tcacttcggc gccgatattg ccgcgaaatg tggagtcgat ttttttgtac
     9181 accagcggcg ctggcgatgt ctcacaccac ggggaaagcg cggcataaac ggcagatgcc
     9241 gcctgatctg cgggcatcgc ccggctttcg gtgttaatga ctaacacatc ggcgcggcgg
     9301 gacggttttt gcgacgcgct caacatgact tccgttctcg cccccttctt cgccaactgg
     9361 acgccggtat cattcgatcc ggtaaaatca tcggcgataa ccatcatttt catgcgtttt
     9421 tctccaaaga agcctgacgc gcctgttttt tcgcaaccca ggaggtcaac actggcgtca
     9481 ggattgccgt ggtgatcacc gaggcggcaa tcagcggagc ggcagcagcg gccacctcgg
     9541 cgagcgaagg gtcggcctgc gcaatagcca gcggcgtcgc aacggcatta cccgcagtgc
     9601 tggaggccgc cgccccggca atgccagttc cgccaaccag acgatctgcg cgaatattaa
     9661 agaaaccgcc aacgaacgtt gtcagcacgc cgagcagaat tccggcaagt ccgccttgca
     9721 gtaacatttc caggttgatg cccgccccca gcgcaaaagc aaagaaagga atgagcagcg
     9781 ggccgccttt ggtcaaaaaa tcgcgcatat gaggatcaag attgccgagg atcatgccga
     9841 caaccagcgg aaccagcacc gccaccagcg ccataatggg aatgttcgcc atccctgccg
     9901 cgcccagcgc aatcatcgta aagaaagggc catcattaag agacaaaata gagatagcgc
     9961 cgacgtcgcg ctcattgccg aattcgccta ccaacgcagc ataaagtccg ccattcgaat
    10021 tgctcatcgc cgcgataatc gccacgccgc tcaggccaaa aataccctcc gcgccgaaaa
    10081 gatgctccac gcccaggcca atgccgatgg cgacaagcaa cttagtgagc gtaatcgtcc
    10141 cgccctgcaa taacgcctgg ggcgcggctt tcacactgat accggctccc atacacagca
    10201 gaaaagcgcc aatcagcggc gccgcgccgt ttttaaataa ggcagtggta aaaccgccaa
    10261 tctcaagcgc ctgcggggcg aaggtgttaa tgactgcgcc aataacgagc ggtacgacca
    10321 tcatgccgcc gggtacgcgc tctattgctt ttttgatgtt catggtctta ccgcctgttg
    10381 cttgttgtga ttgaataaaa tcataacgat tatattcaat caaattaaga tcacaaacgc
    10441 gtcagatcac agttttaaaa tgattaataa aaatcaaaaa atcattctgc aataaaaaag
    10501 ccgggatact cccggctgga atgtgtggtg atttcgtttc cactaccgcc cccaactgtc
    10561 cgtcgacagg cgttgcgggg caataacgaa gagagggtca ggctttactg acgaattccc
    10621 gatacgcggc gacgacccgc agaaaatcct ccatgccgca cagggataaa ctctcttcat
    10681 cgtaataact catcccctct tccatctcat cgccggaaaa atccagctga ttggcgcgaa
    10741 tcatcacttc ttcgccgtcc atccagatcg tgtactcatg ccctgctcgt tgccaggaac
    10801 gttcgctgcc tttgaccgta cgcgcggctt gttctacttc atccagtagc gagaggttgt
    10861 ctttaacctc ttcattaaac cagtgaccga ccacctcgtg gcccatcgac attcgtacca
    10921 aaacccgtcc ggtcacatcg cgcagaaatt cgtaatccat aatgtgttcc tctgcaaagc
    10981 ccttacagtc attatcgcag cagcggagaa gaaaaaaagc gggaacagca ggcggaatga
    11041 aaataaaaac ccaccgcagt tgcgatgggt tttgtaggcc cggtaagcgt agccgccacc
    11101 gggcaataag aggcgtaggc atggtaagcc tgacgccgtc aggcaaatta taccgcagtc
    11161 tggaaaatca ccccatccgc tttctcagtg tactgagaga gctggtcgaa gttcagataa
    11221 cggtaggtat ccaccgccgt cttatccacc tgcgccacaa aggtctggta ctcttccggc
    11281 gtcggcagtt tgccaataag cgctgcaacc gccgccagct ccgcagaagc caggaagacg
    11341 ttcgcaccag tacctaaacg gttcgggaag ttacgggtag aagtggaaac caccgtcgcg
    11401 ccgtcagcca cacgcgcctg gttacccata cacagggaac aacccgggat ttcgatacgc
    11461 gcaccgctct taccaaacac gctgtagtaa ccttcttcgg tcagctgcgc agcgtccata
    11521 cgggttggcg gcgctaccca caggcgggtt ggcaactggc ctttgtggct atccagcagc
    11581 ttaccagccg cgcggaagtg gccgatgttg gtcatgcagg aaccgatgaa cacttcgtcg
    11641 atcttctcgc cctgcacgtc agacagcaga cgcgcgtcgt ccggatcgtt cggcgcacag
    11701 aggattggct ctttgatatc cgccagatcg atgtcgatca ccgctgcgta ttccgcgtca
    11761 gcatcggctt ccagcagctg cgggtccgcc agccattttt ccataccctg gatacgacgt
    11821 tccagcgtac gacggtcgcc gtagccttcg gcgatcatcc acttcagcag gacgatgttg
    11881 gaggtcaggt attcaacgat cggctctttg ttcagcttga tggtacaacc ggcagcggaa
    11941 cgctcggcag aagcatcggt cagctcaaac gcctgctcga ctttcagatc cggcagacct
    12001 tcgatttcca ggatgcggcc agagaagatg tttttcttgc ctttcttctc aacggtcagc
    12061 aggccctgtt tgatggcgta cagcgggatg gcatggacca gatcgcgcag ggtgatgccc
    12121 ggctgcattt tgcctttgaa gcgcaccagc accgattccg gcatatccag cggcatcacg
    12181 ccggtcgcgg cggcaaacgc caccagacca gaacccgccg ggaaagagat accaatcggg
    12241 aaacgggtat gggagtcacc gccggtaccg acggtgtccg gcagcagcat acggttcagc
    12301 caggagtgga tcacgccgtc gcccggacgc agggagacac cgccgcggtt cataatgaag
    12361 tccggcagcg tgtggtgcgt ggtgacgtca acgggcttcg gataggctgc ggtgtgacag
    12421 aacgactgca tgaccagatc ggcggagaat cccagacagg ccaggtcttt cagctcatca
    12481 cgggtcatcg ggccagtagt atcctgagaa ccgacggagg tcattttcgg ttcgcagtac
    12541 gcgcccggac gaatgccttt cacgccgcag gcgcgaccga ccattttctg cgccagagag
    12601 aagccacggc tgctttctgc cacgtctttt gcctgacgga aaacgtcaga gtgcggcaga
    12661 cccagcgctt cacgcgcttt ggtggtcagg ccacgtccga taatcagcgg aatacggcca
    12721 ccggcgcgta cttcgtcgat cagcacgtcg gttttcagtt cgaaggttgc cagcagttca
    12781 tcggtttcat gattgcgcac ttcgcctttg tacgggtaga cgtcaattac atcgcccatg
    12841 ttcaggttag aaacgtcaac ttcaatcggc agcgcgcccg catcttccat ggtgttaaag
    12901 aagataggcg caattttgcc gccgaggcac agaccgccgc cgcgcttgtt cggcacgttc
    12961 gggatgtcat cgcccatgaa ccacagcacg gagttggtcg cggatttacg ggaagaaccg
    13021 gtgcccacca cgtcacccac gtaggccagc gggtagcctt ttttctgcaa tgcttcgatt
    13081 tgtttgatcg ggccgacaac gcctggctga tccggctcaa tgccttcacg ggcgtttttc
    13141 agcatcgcct gcgcatgtaa cgggatatcc ggtctcgacc acgcatccgg cgccggagag
    13201 agatcgtcgg tattcgtttc gccggtcact ttgaaaacgg tgacggtgat tttttccgcc
    13261 agcggcggac ggctcaggaa ccattcggcg tcggcccaag attgcatcac ctgtttggca
    13321 tattcattgc ccgctttggc tttctcttct acgtcgtaga agttatcgaa catcagcagg
    13381 gtgtgagaca gcgctttggc cgcaatcggc gccagtttcg catcgtccag cgcgtcaatc
    13441 agcggatgaa tgttgtaacc accctgcatg gtgcccagca gttcaatggc tttttctggg
    13501 gagaccagcg gggaggtggt gtcgcctttc gcgacagcag cgagaaaacc ggctttaaca
    13561 taagcggctt catcgacgcc aggaggaacg cggttgatca acaggtctaa caggaattct
    13621 tcttcgccca caggcggggt cttcagcagc tcgacaagcg cagccatttg ggttgcgtct
    13681 aaaggtttcg gcacaatccc ctgggcagca cgctcagcta cgtgcttacg gtattcttct
    13741 agcacgacga tatctcctcg ctctcattgt cataatgcgg cgcttttgtt gatgggcgat
    13801 tctcttcacg ctcctgtgag acagtagtta gtagggtaaa tgcccggtac cgcataaggc
    13861 acaataacag gattttcttt aagtgttaat ctgtttacaa aaaagcaaca taaaaaagtg
    13921 gctgaatcgt taaggatggt ctaatgctct actgagacgg gagctgcagc cataaatgct
    13981 tacctcattt cgtgctttga tcgtcacgta acgttaccga tcccaacatt agctaaaaat
    14041 taaactatcg tccctttata ctcacgccaa actgcacccc gtcggcggca ggcataatga
    14101 ccatagcgat tctcgggaat cgggagagat aaaatgacgt tgccctttaa accccatctc
    14161 attgcccttg tgtgcagtgc cgggttattt gccgcttcgg gcgtactgta tgttaaaagc
    14221 cgcgctcccg aagcgcccgc gcaggcggca gctcccacct ctgagccaac gcagaccgct
    14281 gtgcccgcgc ctgtcgcgaa aacgaccttt accactgcgc aaatcgatca atgggtcgcg
    14341 cctgtcgcgc tttatcccga tgccctgctt tcgcaggtgc tcatggcctc cacctacccg
    14401 gcgaacgtgg ttcaggccgt ccagtggtcg cgggataacc ccacgctgca gggcgatgcc
    14461 gctattcaag cggtggccag ccaaccgtgg gaccccagcg tcaaatcgct ggtcgccttt
    14521 cctcagttga tggcgcttat gggcgagaat ccgcaatggg tgcaaaacct gggcgatgcg
    14581 ttcttagccc agccacagga tgtgatggat gcggtgcaaa ggctgcgtct gctcgctcaa
    14641 caaaccggtt cgctaaaatc cacgccacag caaaccgtca ccagcgtgcc gaagtccagc
    14701 gcttctaccg ccgtcacgac gacaaccacc acatccgcca gtacgccagc aacaccgtcg
    14761 accgtcatca aaattgaacc tgcgaatccg caggtggtgt acgtgccaaa ctataacccc
    14821 acgacggtgt atggcgcctg gcccaatacc gcttatccgc cggtgtattt accgccccct
    14881 ccggggcagc agtttgccga cagttttgtt aaaggttttg gttatagtct gggcgtcgcc
    14941 accacctatg cgttgttcag cagcatagac tgggatgacg acgatcatca ccaccatgac
    15001 gacgaccatc atgatgatga ttaccatcat ggtggtaacg gttatcaaca taatggcgat
    15061 aatatcaaca tcaatgtcaa taatttcaac cggatatccg ggcaaaacct gccgggccaa
    15121 acgatgggct ggcagcataa tcccgcctgg cgcaatggcg tcccctatcc gaataatacc
    15181 gttgcgcaac ggttccatcc caccaatgtt agcggcgggt taagcgcaac gcagcaagcg
    15241 ccagtgtctc gcgacagtca gcgccaggca gccatggcgc aattccaaca gcgcagccat
    15301 acatcacccg ctaacgtgtc aggcgagaca tcccgcgaca gacagcgcaa agcggcatcg
    15361 cagcagttaa atcaaattgc ccagcgtaat aattaccgtg gctatgacgg aacacaaaac
    15421 agcagtcgtc gcgaggcggc gcagcagaca ctgaataaat ccaccacgca gcagcatcgt
    15481 tccgagctga aggctaaagc ccagcagcac cctgtttcac aacagcagag agacaccgcc
    15541 cgccagcgta ttgaatcctc tacgccacag cagcgtcagg catttcgcca gaatatgcac
    15601 gccaatgtgt ttagcgggaa cgacagtcga tcgccgtcat ggcaatcgca acagctacgc
    15661 ggcctagaaa gccgtcgcgg cagtcacttg aacaccgagc aacgcgccgc cgcgcgggaa
    15721 catttttctg aacatcatga atttcatcgc cgttaaccgg agcagataat gaaaaaggtt
    15781 atgttaagcg ctctgttact gtcgttaccc ttgctgggct acgcgcagga acggttcccc
    15841 tccccggaag cggccgccag cgccttcgcc gcggcggtag ccggaaaaaa cgaaacgcag
    15901 cttaccgcgc tactgggcga tgactggcgg caatttctgc cgccggaagg tgccgatccc
    15961 gaggccgtgg cccgcttcaa tcgtgactgg cgcgaaggcc atcgcattgt acaaaaagac
    16021 aatacggcgc acctgaatgt cggacgagaa gactggcagc tcccggtgcc catggtgaaa
    16081 gagactggcg gctggcgctt tgatatggcg gcagccggga atgagatcct cacccgtact
    16141 attgggcgaa atgaactttc taccttacag gccatgcatg cttacgttga tgcgcagcag
    16201 gactattact tacaaaacca tcgctgggcg cacaggataa tcagtagcga aggccaaaaa
    16261 gatggcctgt actggccaac caaagcaggc gacgtcccca gtccgttagg cccaaacttt
    16321 agtcccgcag cgccagacga gggttaccac ggctaccatt tccgtattat cagcgataac
    16381 gacggtcacg gtgcggcgct tctggcctgg ccgatgcatt acggcgaaac cggggtgatg
    16441 agttttatgg tcaaccagga cgatcgtatt tatcaggcgg atttaggcaa ggagacggag
    16501 agtaaagttc aggctatcac gcgttttgcg ccagacgcgc agtggcaggt cgccgaataa
    16561 cccgtaagcg cctggcgtta tcgccaggcc gtgatcatta gccctgatgc ggcatcaatt
    16621 ccgggtggcc ttgtaccggc ggcttgttgc tggtcagcgc ggcttcatca gcctgaatgc
    16681 tgccggaatt ggccgcccat acgccttcat gcgtgtgggt gatctgctga tgctgcgcat
    16741 tcaaatcctc gcccattgcc gcaatatgcg tgctttccgt accgccgctg ttagtcgccc
    16801 aggggatgac gggatcgctg gcaaatgcca tgccggaaat caaggtcgca gttagcgctg
    16861 ccgttgtcag aaaaagtttc atatatcaaa cctcataatt agctcgctat tattttatag
    16921 cgttaccaat ttcaggatga tgacaaatta aggagaggta tttcttatga aacaattagt
    16981 tggtcgaaaa tgacagacaa aggcactacc gacggcataa gctttgaaaa acgtactgct
    17041 gcggaaagga taaattttgc ggtttcgtta tccttcgcca tcatttgaca catctgattt
    17101 gccatgcata aaaaaagcgg ctgtaaagcc gcttttctgt atcgggtggc gcattgccac
    17161 ccgcagaaga ttatttcttc ttcgctttcg ggtttggcag gtcggtaatg ctaccttcga
    17221 agatttccgc cgccaggccc acggactcat gcagagtcgg gtgagcatgg atggtcagcg
    17281 cgatatcttc cgcgtcacag cccatttcga tcgccagacc gatttcaccc agcagctcgc
    17341 cgccgttggt accgacaatc gccccgccga tcacgcggtg agattctttg tcgaaaatca
    17401 gtttggtcat accgtctgcg cagtcagaag cgatagcacg gccagaagct gcccacggga
    17461 aggtggcggt ttcatagctg atgccttttt ctttcgcttc tttctcggtc aggccaaccc
    17521 atgccacttc tggctcggtg tacgcgatag acgggataac tttcggatcg aagtagtgtt
    17581 tcttcccggc gataacttca gcggcaacgt ggccttcgtg aacgcctttg tgcgccagca
    17641 tcggctgacc gacgatatcg ccgatagcga agatgtgcgg cacgttggtg cgcagctgtt
    17701 tgtcgacgcg gataaagcca cggtcgtcaa cttccacgcc agctttgccc gcgtcgaggt
    17761 ttttaccgtt cggcacacga ccaatcgcca ccagaaccgc atcataacgc tgcgcttcag
    17821 ccggggcttt tttgccttcc atcgaaacgt agataccgtc ttctttcgct tcaacggcag
    17881 tcactttggt ttccagcatc aggttgaatt tcttgctgat gcgtttggtg aagactttaa
    17941 cgatgtcttt atcagccgcc gggataacct ggtcgaacat ttcaaccacg tcaatctctg
    18001 aacccagcgc gtggtatacg gtacccattt ccagaccgat gataccgccg cccatgacca
    18061 gcatacgctt cggcacttct ttcagttcca gagcgtcggt agaatcccat acgcgcgggt
    18121 cttcatgcgg aataaacggt aattggatcg gacgagaacc cgccgcgatg atcgcgttat
    18181 cgaagttgat cacggttttg ccattttcgc cttccacttc cagggtatta gccccggtga
    18241 atttacccag accattgacc actttcactt tacggccttt ggccatacca gccagaccgc
    18301 cggtcagctg cgtgatcact ttctctttcc aggtacgaat cttgtcgata tcggttttcg
    18361 gctcgccgaa gacgataccg tgttcagcca gcgctttggc ttcttcgata acttttgcta
    18421 cgtgcagcag cgctttagaa gggatacagc cgacgttcag acaaacaccg ccaagggtgt
    18481 tgtagcgttc tacaattacg gtttccagac ctaaatcagc gcaacggaaa gcggcagaat
    18541 agcctgccgg gcccgcccca agtaccacga cctgagtttt gatttcagta ctcatcatga
    18601 cctctttatt tgtatccggc ggtccggggt acttgatcgc ccatcatcca ccgggtcgtt
    18661 ctatccgccc gtatcttaca aaattgttaa caattttgaa acaacaaacg gatcacgaat
    18721 tatcgctttc gctaataacc tcacaaactc catgagatta tcaaaaaaaa gccggccgtc
    18781 gggccggctt tttcgcttac atcaccagac ggcgaatgtc agacaacata ttgttgataa
    18841 tggtaatgaa acgcgcacca tcagcaccat cgatcacacg gtggtcgaaa gaaagagaga
    18901 taggcatcat cagacgcggc acaaactctt tcccattcca caccggttcc atcgccgact
    18961 tagaaacgcc gaggatagcc acttccggcg cgttgacaat cggcgcaaag tgggtagttc
    19021 ccaggccgcc gatgctggag atagtgaagc aaccaccctg catttcgcca gcggtcagct
    19081 taccatcacg cgcttttttg gagatggtgg tcagttcacg agacagctcg gtcacgctct
    19141 tcttattcac gtctttaaag accggaacca ccaggccatt cggggtatca accgccacgc
    19201 cgatgttgat gtattttttc agggtcagac gctgaccgtc ttcggataga gagctgttga
    19261 agcgcggcat ctgttccaga gcagcggcaa ccgctttcat gatgaagacc actggcgtgt
    19321 atttcacatc cagtttgcgc ttctcagctt cggcgttctg ctgtttacgg aacgcttcca
    19381 gatcggtgat atcggttttg tcgaagtgcg taacgtgcgg gatcatcacc cagttacggc
    19441 tcaggttcgc gccagagatt ttctggatac ggcccagttc cacttcttca acttcaccaa
    19501 acttgctgaa gtccactttc ggccacggca gcatacccgg gataccgccg cccgcagcag
    19561 ccggcgcagc ttccgcgcgt ttgatagcgt ctttcacgta agcctgaacg tcttcgcgca
    19621 gaatacggcc tttacgacca gtgcctttca ctttcgccag gttgacgcca aactcgcgcg
    19681 ccagacggcg aatcagtggg gtagcgtgaa cgtaagcgtc gttttcagcg aactcagatt
    19741 tgccttcggc tttggcagcc ggggcagcag gcttctcagc tttcgccgcc ggagccggcg
    19801 ccgctgcttc ctgtttagcc ggagcggccg caggcgctgc gccttccact tcgaagacca
    19861 taatcagcga gccggttttc actttatcgc cggtgctgat tttgatttct ttcacggtgc
    19921 ccgcgaacgg cgcaggcact tccatagagg ctttgtcgcc ttccacggtg atcagcgact
    19981 gttcagcggt aactttatcg ccgactttga ccatcacttc ggtgacttca acttcgtcgc
    20041 cgccgatgtc cggtacgtta acgtctttca cgcccgtcgc tgctgctgga gcagccgcag
    20101 ccggagcggc ttccgctttc gctggtgctg ctgcgcccgc ttcacccgcc acttcgaaga
    20161 ccataatcag agagccggta gacactttat caccggtgtt cactttgatc tctttcacgg
    20221 tgcctgcaaa cggagcagga acttccatag aggccttgtc gccttcgacg gtgatcagcg
    20281 actgttcagc ttctacggtg tcgcccactt tcaccatcac ttcagtcact tcaacttcgt
    20341 cactgccgat atccggaacg tgaacgtctt tcgccgctgc cgcagcaggt gctgctgccg
    20401 gcgccgcttc tttcttctct tctgcctgag caggcgcagc gtcagctgca ccgtcggcgg
    20461 aatcgaaaat catgataagt gcaccggtct cagttttgtc gccgacagag actttgatct
    20521 ctttcacgac gccagcctgc ggagacggga cttccataga ggctttgtcg ccttctacgg
    20581 tgatcagcga ctgttcagct tcaactttgt cgcccacttt gaccagaatc tcggtgattt
    20641 caacttcatc tgtcccgatg tccggtactt tgatttcgat agccattatt cttttacctc
    20701 ttacgccaga cgcgggttaa ctttatctgc atcgatgttg aatttggtaa tcgcatccgc
    20761 taccactttc ttgtcgattt cgccacgttt agccagttcg cccagcgctg cgacaaccac
    20821 ataagaagca tcaacttcga aatggtgacg caggttctca cggctgtcgg aacgaccgaa
    20881 gccatccgta cccagtacgc gatagtcgtc agccggtacg taagtacgaa cctgctcggc
    20941 gaacagtttc atatagtcag tagatgccac agccggagcg tcgttcatca cctgagcgat
    21001 gtacggtacg cgcggggttt ccagcgggtg cagcatgttc cagcgctcac aatcctgacc
    21061 atcacgcgcc agttcggtga aggaggtcac gctatatacg tcagaaccta cgccgtaatc
    21121 tttcgccagg atctctgccg cttcacggac gtgacgcagg atagaaccgg agcccagcag
    21181 ctgaacttta cctttgctac cttcgagggt ttcgagtttg tagatacctt tacggatacc
    21241 ttcctcggca cctgctggca ttgccggcat gtggtagttt tcgttcaggg tggtgatgta
    21301 gtagtaaacg ttctcttgtt tttcaccgta catacgctcc agaccatcat gcatgatgac
    21361 agccacttca taagcgtaag ccgggtcgta agagatacag ttcgggatag tcagcgactg
    21421 aatgtggctg tgaccatctt cgtgctgcag accttcgccg ttcagcgtag tacgaccgga
    21481 agtcccgcca atcaggaagc cgcgagcctg ctggtcgcca gcctgccagc acaggtcgcc
    21541 gatacgctgg aacccgaaca tagagtagta gatgtagaac gggatcatcg gcagatcgtt
    21601 ggtgctgtaa gaggtcgccg cagccagcca ggatgcgcct gcgcccagct cgttgatacc
    21661 ttcctgcaga atctggcctt tctcgtcttc tttgtagtaa gcaacctgct cacggtcctg
    21721 cggggtgtac tgctggccgt tcgggctgta gataccaatc tgacggaaca gaccttccat
    21781 accgaaagta cgcgcttcgt cggcgatgat cggaaccaga cgatctttga tcgacttgtt
    21841 cttcagcatc acgttcaggg cacgcacgaa agcgatcgta gtggaaatct ctttactttg
    21901 ctcttccagc agcgcgccga aatctgaaag ttgaggcagc tctaacttct cggtgaagtt
    21961 cggctgacgg cttggcaggt agccgtgcag cgcctgacgg cgttcatgca ggtatttgtg
    22021 ttcttcagaa ccttccggga aggtaatgta cggcagtttt tcgagatcag catcggcaac
    22081 cggcacgttg aaacgatcgc ggacgtaacg cacgccgtcc atgttcattt tcttaacctg
    22141 gtgagcgatg tttttacctt ccgcggtgtc acccatgccg taacctttaa tggtatgggc
    22201 caggattacg gtcgctttgc ctttggtttc ctgcgctttt ttcagtgccg cgtagacttt
    22261 cttcggatcg tgaccaccac ggttcagcgc ccaaatctgc tcgtcagtcc agtcggccac
    22321 cagcgcggcg gtttccggat atttaccgaa gaagtgctca cgcacgtaag cgccgtcttt
    22381 ggatttgaag gtctggtagt cgccgtcaac ggtttcgttc atcagctgga tcagtttacc
    22441 gctggtgtct ttacgcagca gttcatccca acgaccgccc cacatgactt tgataacgtt
    22501 ccagccagca cctgcaaaga tgccttccag ttcgttaaca atcttgccgt taccggtgac
    22561 cgggccgtca agacgctgca ggttacagtt gataacaaaa accaggttgt ccagtttttc
    22621 acgggtggcg atggtgatcg cgcctttgga ttccggctca tccatctcgc cgtcgccgag
    22681 gaaggcgtaa acggtctgtt tagaggtatc tttcaggcca cggtgttcca gatatttcag
    22741 gaatttcgcc tggtagatag caccgattgg gcccagcccc atagagacgg tcgggaactg
    22801 ccagaattcc ggcatcagtt tcgggtgcgg ataggaagag aggccattgc cgtgaacttc
    22861 ctgacggaag ttatccatct gttcctgggt cagacgacct tccaagaacg cgcgagcgta
    22921 gatgcccgga gagatgtggc cctggaagta caccaggtcg ccgccatcct gttcgttgcg
    22981 cgcacggaag aaatggttaa aacagacatc atagatcgtg gcggaagact ggaaggacgc
    23041 catgtggccg cccaactcaa ggtctttttt agacgcgcgc agcacggtca tgatggcgtt
    23101 ccagcggatc gcagaacgaa tgcgacgttc cagctccaga ttacccgggt attccggttc
    23161 gtcttcaacg gcaatagtgt tgatgtaatt actggcccct gcgcctgccg cgactttcac
    23221 gccgccttta cgagcttcag aaagcagttg gtcaatcaga tactgagcgc gctcaacacc
    23281 ttcttcacgg ataaccgatt cgatcgcctg tagccagtcg cgagtttcga tcggatccac
    23341 gtcattttgg aaacgttctg acatgggggt attccttatc tatctaatac gttgagttat
    23401 ctggaacctg tcccattaaa ctttcgtcag aaagcttaat aagacaggtt ctgcgtttag
    23461 ttgccgcgca catttttgcg cgttattcac aacatcttct ggttaacgtt ctgccagaaa
    23521 aaactaattc ttgcgctgtt ccaggcggcg taaagcgcgt tcacgacggc tctcctcacg
    23581 gcttctgtcc agcataatct cttcgataaa cgccagatgt cggtgtgacg cttcacgcgc
    23641 ttcttctggt tttccggcca taatggcttc aaatatacgg gtgcgatgcg tgctcaccag
    23701 cggcagcatc tcccgacgcg catacagcaa ttcgaagttc tgccgcacgt tttgcgccag
    23761 catcggctcc atacacctta gcagatgaag caataccacg ttgtgcgccg cttcggtgac
    23821 ggcgatttga tactggagca cggcttcgga ctcggcatcc agatcgccgg actcttgcgc
    23881 cagctcaata gcgtggtgca gctcgcgaat acggtcttta tcttcgtcgg tgctgcgcag
    23941 cgccgcgtaa taagccgcaa tgccttccag cgcatggcgc gtttcgagca ggtcaaactg
    24001 ggattcaggg tgatcggaga gcagttccac cagcgggtcg ctaaagctct gccacaggct
    24061 gctctgcacg aaggttccgc cgccctggcg acgaagcaac aatcccttcg cttcgagacg
    24121 ttgaatcgcc tcgcgcaagg agggacggga gacgtcgaac tgttttgcca gttcacgttc
    24181 cggtgggagt ttttctccgg gacgcaatgt tccctcaagg attaaaaact ccagctgctg
    24241 ctcgatcaca tcggagagtt ttggttggcg gattttgctg taggccatga tttcctgtct
    24301 taagccattt gcccggagtc aattggtctt accaatttca tgtctgtgac gctaaagtaa
    24361 caaagtattc accttctgtc catacaggtt ttgattgaaa tcagtaaagg aggcacattt
    24421 taacaatttt acagaaatca cgtttcaaaa ctgtaactgt gcacaaatgt taaatttacc
    24481 caccaggagg tagatttaac gtatttgaaa cgataaaaaa tctcatctga accgattcaa
    24541 cagcagatca aatgcatttt tatgcataaa taatgaataa aaacaaatta acctttagaa
    24601 gggaaaataa aaggaggtat ttacaagtgc tttcttttta cgcaactcgt catcacccct
    24661 gcacaaagca ggtgcattcg cggccacata ccattattct gatcaagacg aaagagttga
    24721 agtgacattt taaaaaacga gcttgtaaat aaatcaatac aaaaagcgga attgcaaact
    24781 tacacacgca ctactgcatc gttcaaaata agcgcgttat gaataaaccg cgcccgatac
    24841 acgaggtttt atgatggaca gtcagcagca cggcgagcag ctcaagcgcg gcctgaaaaa
    24901 ccgccatatt cagcttatcg cattgggcgg cgcgataggg acaggcttgt tcctgggaag
    24961 cgcctccgtt attcagtcgg cggggccagg aattatcctg ggctatgcga ttgcaggctt
    25021 tattgccttt ctgattatgc gccagctggg agagatggtg gttgaagaac cggtcgccgg
    25081 ctcttttagc cacttcgcct ataaatactg gggcggcttt gccggattcg cttccggctg
    25141 gaactactgg gtgctgtacg tattagttgc catggcggaa ctgaccgcag tgggtaaata
    25201 tatccagttc tggtatccgg agatccccac ctgggcttct gcggcagcct tctttgtgat
    25261 tatcaacgcc atcaacctga ccaacgttaa agtgttcggt gagatggagt tttggttcgc
    25321 cattattaaa gtgatcgccg tcatcgctat gattctgttc ggcgcgtggt tactcttcag
    25381 cgataccgct ggtccgcagg ccaccgtgcg caacctgtgg gaacagggcg gctttctgcc
    25441 gcatggctgg accgggctgg tgatgatgat ggccattatt atgttttcgt tcggcggact
    25501 ggagctggta gggatcaccg ccgctgaagc cgataacccg gaacagagca tccccaaagc
    25561 taccaatcag gttatctatc gcatcctgat tttttatatc ggctcgctgg cggttctgct
    25621 ttcgctgctg ccatggactc gcgtcaccgc cgataccagc ccgtttgtcc ttatcttcca
    25681 tgagctgggc gatacgtttg tcgccaatgc gctgaatatc gtggttctca ccgccgcgct
    25741 atcggtttat aacagctgcg tttactgcaa cagccgtatg ctgttcggtc tggcccagca
    25801 gggaaatgcg ccgaaagcgc tgctgaacgt cgacaaacgc ggcgtgccgg tgagctccat
    25861 tttggtttcc gccgtcgtga cggcgttgtg cgtgctgctc aactacctgg ccccagagtc
    25921 cgcattcgga ctgctgatgg cgctggtggt ctccgcgctg gtcattaact gggcgatgat
    25981 tagccttgcc catatgatgt tccgtcgcgc gaaacagcag cagggcgtga aaacccgctt
    26041 cccggccctg ttttatccgt tcggcaacgt tctctgcctg ctgtttatgg cggcggtatt
    26101 gatcattatg ctgatgacgc caggtatggc gatctccgtg tggctgattc cggtatggct
    26161 gctcatcctg ggcgtcggct acctgtgtaa agaaaaaacg gcaaaaacgg tgaaagccca
    26221 ctgatcgtgg cgttactttt ccgccctccc cgtccgggga gggtgttatc tgcctcacag
    26281 tttcccacgt ataaccattt tatccatatc agcggcgtga tcctgctacg caaaaaaaag
    26341 ctcgcaggcg aataattacc gccatcatct gatggggaga agtctcaatg gataagggca
    26401 gactttcggt aagagagaaa atcgggtatg gcatgggtga cgccggatat aacattattt
    26461 ttggcgctat catgctgttt gttaattact tttatacgga tatttttggt cttgccccag
    26521 cgttagtcgg tgttttactc ctttcagtac gcgttatcga tgccgttacc gatccggtga
    26581 tgggcgcgct tgccgatcgt acccaaagta aatatggtcg tttccgcccc tggctactgt
    26641 ggattgcatt tccctacgcg ctgttcagcg ttctgatgtt cacgacgccg gactggggct
    26701 ataacagcaa agttatctat gccttcgtca cctattttct gctttccgtg acctataccg
    26761 ccatcaatat tccctattgc tcactgggcg gcgtgatcac taacgatcca aaagagcgcg
    26821 tagcctgtca ggcttatcgc ttcgtgttag tcggcatcgc gacgctgttg ctatcgttaa
    26881 cgctattgcc gatggtggac tggtttggcg acggcgacaa agccaaaggc tatcagttgg
    26941 cgatgaccgt gctggcgatt atcggcatgg gtatgtttct gttctgcttt gccagcgtcc
    27001 gcgaacgcgt tcgccctgcc gttccgacgc acgatgatat gaagaatgat ttcaaagatg
    27061 tgtggaaaaa cgatcaatgg gtacgcattc tgctattgac cttatgtaac gtctgcccgg
    27121 ggtttatccg tatggcggcg accatgtatt acgtcacctg ggtgatggga caaagcaccc
    27181 atttcgctac gctttttatt agtcttggcg tggtcggtat gatgatcggc agtatgctgg
    27241 caaaagtctt aaccgatcgc tggtgtaaat tgaaggtatt tttctggacc aatatcgcgc
    27301 tggcgatttt ctcctgcgcg ttctatttct ttgacccgaa agccaccgtg atgatagtgg
    27361 cgctctactt cttgctcaat attctgcatc agatcccttc cccgttacac tggtcgctga
    27421 tggcggacgt cgatgattac ggcgaatgga aaaccggcaa acgcattacc ggtattagct
    27481 tctccggtaa tctgttcttc ctgaaactgg gcctggcgat tgccggggcg atggtcggct
    27541 ttttgctctc ctggtacggt tatgacgcca gcgccaaagc gcaaagcgcc tcggcgatga
    27601 acggtattat gctgttgttt accgttatcc ttggcgttgg ctatctgatt accgcaggcg
    27661 tggtacgtct gctgaaagtt gaccgtgaac tgatgaaaaa aatccaggac gatttggaaa
    27721 aacgtcgcac taattaccgc gaattgagtg agttgcagga gctcaaagcc gctgaaagcg
    27781 taaggaaagc ctgatggcaa actggccaaa cccgtttatt gaacaacgtg ccgatccgtt
    27841 tattttacgc gacggcagcg attactactt tattgcctcc gtaccggaat atgacaggct
    27901 ggaaatccgc cgggctgatt cgctggaagg gttgcgcgcc gccgaccccg ttgtcgtctg
    27961 gcgcaaaccg gaaagcggcc cgatgagcca gctcatctgg gcaccggaaa tgcaccgcat
    28021 caacggtaag tggtacatct attttgccgc tacccatact caagcgcttg ataaactggg
    28081 aatgttccag caccgcatgt ttgccctgga gtgcgccgat gccgacccac tcaccggcaa
    28141 gtggacggag aagggtcaaa ttaaaacgcc gtttgatacc ttctccctcg atgccaccac
    28201 tttttatcat cagggaaaac agtggtatct gtgggcgcaa aaagcgccgg atattgccgg
    28261 taactcaaat atttatctgg ctgaactgga aaatccgtgg acccttaaag gcgagccggt
    28321 aagactcagt aagccagagt acgactggga atgtcggggt ttttgggtta acgaaggtcc
    28381 ggccgtcgtg gtgcatggcg acaagctgtt tatcagctat tcggccagcg ccaccgatga
    28441 aaactactgt atggggttac tgtggattaa cgtaaacgac gatccgcgcg atccggccaa
    28501 ctggcataaa tcaccgcgcc cggtctttac caccagctat gaaaatcgcc agtatgggcc
    28561 gggacacaac agctttacgc aaacgtcgga aggtgaagat gtactggtgt accacgcgag
    28621 aaattacacc gaaattgaag gcgatccgtt gtacgatccc aaccgccata cgcgtctgaa
    28681 acgggtgcgc tgggacgaaa acgggatgcc tgattttggc gtgccgccag ccgatacgat
    28741 ctaagccgtt gcactgcccg gtggcgctag cgcttaccgg gcctacagat ttttccattg
    28801 taggcagcat aagcgttagc gctatcggca caacattaca ctaatgcccc ataaatggtg
    28861 agcaacgcaa taatcaccac caccacaaac gaggccttct tcgccatcga taccgccgct
    28921 ttgggggttt ctactttgtc agtatgcggt tcgcgcacca gtgagaactg cgccagacgt
    28981 gtgagcacct gatattgcga agtatgcaga tccgccagcg aggcaaacca ggccggcaac
    29041 gctttctcgc catgccccag taatgcatac actacgcccg ccagacgtac cggaatccag
    29101 tccagtacat gaagaatagc gtcaatgccg gattgcaaac gttggtgcgg cgtctgatag
    29161 cgcgccagcc aggtctgcca ggcccgtaaa aacgcatagc ccaccagcgt taccggcccc
    29221 cacggaccgc caacgataaa ccaaaatagc ggtgcgaggt aaaaacggaa atttatccat
    29281 aacaacgcgt tttgcagctc acgcaaaaac tcacgctcat tacaatccgg cggcacgccg
    29341 tgaatcagcg taagctcgct ggccatcgcc tcgcaaggat gcggatcgtt acgggacgcc
    29401 gctttcagcc aggcgtgata atgtactcgc actttgcccg cgccgataca cagcacgccc
    29461 aggagaatcc acaccaccag cgtcggcacg ttaaatagca gcccttttaa cgcctggagc
    29521 agtagaaaag tcaccaccat cgcgatcgcc gtcattccca tcgtgcgcaa catcgaaaaa
    29581 tgcgtaatcc gacggaatag cgcctccagc cgatgatcga gctgccagtg ctcgcccagc
    29641 ttaaacaggc gctcgacaat cagcaccagt aatgtcgtaa acagcgtcat gtcatctcct
    29701 tgtgcgacga aagggctacc aaagcgcgaa agcgcggcca gtcaaaggca gggccagggt
    29761 ccgttttgcg gtcaggcgca atgttgcagt gtccggtcat attgtcggcg atcgccggat
    29821 agcaagcgat aagcgtgcgc gtcacggcgg ctagctgctg atactgcgca tcggtataag
    29881 ccagcgtatc cgtcccctcc agctcaatac caatggagaa atcattacaa cgttcccgcc
    29941 cctgatagtt tgatacgccc gcatgccacg cacgcttatc aaaaggcaca tactggacga
    30001 tttcaccgtc gcgacgaatc agacaatggg ccgaaacacg aagatgagcg atttctgcaa
    30061 aaaaaggatg ggcgtctgga tctatcgttc cggtgaataa tgcatcgatc cacggaccgc
    30121 caaactcgcc ggggggcagg ctaatattat gcaccaccag caaggacggt ttttcgtcat
    30181 ccggacggca atcataatgc ggagaaggga cgcgtcgcgc ctctaccaac caacccttat
    30241 ctggcaacat gcggagtctc cttttgagtg gtgcttatag ctgcttcaga gtagcatgtt
    30301 tctaccttat gattcgttag caatttggag ttttatcatg ccgcctcgcc gttataaccc
    30361 agacgaccga cgtgacgcgc tactggaacg cattaatctc gatatccctg ccgccgttgc
    30421 tcaggcgctg cgtgaagatt taggtggaga agtcgatgct ggcaacgata tcaccgcgca
    30481 acttttgccg gcagatacgc aagcccatgc cacagtgatc actcgtgaag acggcgtttt
    30541 ctgcggcaag cgctgggttg aagaggtctt catccaactg gcgggcgatg atgtgcgcct
    30601 cacctggcat gtcgatgacg gcgacgccat tcacgccaac caaacagtgt ttgaactgaa
    30661 cggccccgct cgcgtattgc tgaccggcga gcgcacggcg ctaaactttg tccagaccct
    30721 ttccggcgtc gccagtgaag tacgccgcta cgttggacta ttggctggca cccaaaccca
    30781 gttgctcgac acgcgtaaaa cgctgccggg tctgcgcacc gcgctcaaat atgcggtttt
    30841 atgcggcggc ggcgccaatc atcgtctggg tctcactgac gcgttcctga ttaaagaaaa
    30901 ccatatcatc gcctccggtt cggttcgtca ggcggtggaa aaagcgttct ggctacatcc
    30961 ggacgtgccg gtagaagtcg aggtcgaaaa tctggatgaa ctggacgatg cgctgaaagc
    31021 aggcgcggat atcatcatgc tggataattt caacaccgac cagatgcgcg aggcggtgaa
    31081 acacgtcaac ggccaggcgc ggctggaagt atccggcaac gtcaccgcgg aaaccttacg
    31141 cgaatttgct gaaaccgggg tggatttcat ctccgttggc gcgctgacca agcacgtgcg
    31201 cgcgctcgat ctctccatgc gtttttgctg atcctctccg cccgatggcg ctgcgccgtc
    31261 gggtctataa atcacctgtc cgtagatccg cgtcgtgatt cggtaaaata ttcgtagcgc
    31321 ctcgcaataa cgttgccgtg tcatgtaacg cagcgaaaat cttcagaatc cgccttcccg
    31381 ttttaccttt tgccgctcgc ccgctcttcc cttgtttgcc acagtagcgc cggctaactc
    31441 aaggagcgaa caatggaaaa acaacgcggt ttcacgctta tcgaactgat ggtcgttatt
    31501 ggcatcatcg ccattttaag cgccattggc attccggctt accagaacta tctgcgtaaa
    31561 gcggcgctga cggatatgtt gcaaacattt gtcccctacc gtactgccgt cgaactctgc
    31621 gctctggaac atggtgggac gagcacatgc gatgcgggcg tcaacggtat cccctcgccc
    31681 gtcatcaccc gttatgtttc gggcatgagc gtggaaaaag gcgtcatcac gcttaccggt
    31741 caggagagtc tgagcgggct tagcgtcatc atgacgcccg cctgggacaa tgctaacggc
    31801 attaccggct ggacgcgtaa ctgcaatatt caaagcgaca gcgcgttaca acaggcttgt
    31861 gaagatgtct tccgttttga cgccaactaa ggagacaaga tgaaagacgc tcagctcaac
    31921 accttgtgtc aacgtcatca ggctgtactg atcaatagcg ccagcaacag tatcactgtt
    31981 gcggtggtcg acgcgccctc tcatgcgtta ttggacgctc tgcatttcgc cacgcaaaaa
    32041 cagattgata ttgtgtgctg gactcgccag caaatggaaa atcatcggca taagccggat
    32101 caggcaccct cgacaaacgc cgcgaaaggc ggagaaaccg cggcccagct tctcaatcag
    32161 acattacgct cggcgatggc gaaacgcgcc tctgatatcc atctcgaacc cggcgccagc
    32221 cgctaccgga taaggctccg catcgatggc gttcttcata ttctgcagga catcgccaaa
    32281 gagacggggc ttgcgctgac ggccagattg aaagtcctag gaaatttgga catcgctgaa
    32341 catcggctgc cgcaggacgg gcaatttacc gttgacctga cgggcgacag catctctttt
    32401 cgtatcgcca cgcttccctg taaagaaggc gaaaaagtcg tcttacggtt gttgcatcag
    32461 gttgaacaaa cgctggatct ggacacgctg ggcatgtacg gggcacaact taccgctttt
    32521 agacaagccc tacagcaacc tcaggggctg gtactggtga ctggccccac cggtagcgga
    32581 aaaacggtca cgctatacag cgcgctacaa acccggaata cgccgggtat caacctctgt
    32641 agcgttgagg atccgataga aattccactg gatgggatta accagacgca gatccatccc
    32701 cgcgccgggc tcacctttca aaatgtgctg cgcgcgcttt tacgccagga ccctgacatc
    32761 atcatggtag gtgaaattcg tgacggcgac accgcagaaa tcgccattaa ggcggcacaa
    32821 acgggccatc tggtactttc aacactccat acgaactcca ccagcgaaac cctgatacgt
    32881 ttgcagcaaa taggcgtaac acgctggatg atctcatcgg cgcttacgct ggtggtagcg
    32941 caacgcctgg taaggaagct ttgcccgcac tgcaaacagc gtctgagcga tcccgtggtg
    33001 ctatcgccca atctttggcc cagcgcgcta ccgcgctggc aggcaaacgg ctgtcagcat
    33061 tgctaccacg gcttttatgg ccgaaccgcg ttattcgaag tgttaaccgt taccccggca
    33121 ttacgtcagt taattgcgag cggcgcatcg gcgcaagcac tggaagccca cctccagcag
    33181 accggtacag ggacgctttt tgaaaatggc tgtcgcgccg ttgagcaagg catgacgtcc
    33241 tttgaagaga tactgcgcgt tctgggaatg ccccatgagc gttaaacagc tctggcgctg
    33301 gcaaggcgtt aacgataaag gtcaactgga acaagacgtt gtatgggtgg acaatcgtct
    33361 ggcgctgatc atcaccctgc aacatcagcg cattatgccg cttcgcatca agcgcataag
    33421 cgttaacgcc gcactgtgga aagaagagca aagcgctgaa attattcatc agttggccac
    33481 gctcattcat gccggactga cgctttctga agggctggaa ctccttgcga aacagcatcc
    33541 ccaccgacaa tggcaagcgc tgttgcgcac gctggctcac gagcttgaac agggcgtccc
    33601 tttttccagc gcattagtct cctggccgca ggtatttccg ccgctctacc agacgatgat
    33661 ccgcaccgga gaactgaccg gcaaactggc cgaatgctgc tttgaactgg cccgtcagca
    33721 aaaagcgcaa cggcagatta cggttagcgt gaaaaaggcg ctgcgctatc ccgccattat
    33781 tctaacaatg gccgccctgg tcgttttcgc catgctgcac tttgtcctgc cggaatttgc
    33841 cgccatttac cgtagcttca ataccccgct tcctcttctg acacgcggta ttatcgcgat
    33901 agcgcaatgg gggccggcat ggggttggct catcttgttc ctgacgatgc tcgttgctat
    33961 cgctcaccgc aggttaaaac aaaaaccgtc ctggcaagcg cagcggcagc gtcttctgct
    34021 acggcttccc gttatgggtc gcctgataag aggccagaaa ctagcgcaaa tattcaccgt
    34081 actggcatta acccaaagcg caggcattcc ttttcttcag ggactggaaa gcgctatcga
    34141 tagtctcggc tgcccttact ggtcacagcg tttaacgcag gtacatcagg agatcgccgc
    34201 gggcaatccg gtctggttgg cgctaaaaaa tacccaggaa tttagtccgc tatgcctgca
    34261 actggtcaga acgggcgaag cgtccggttc actcgatatc atgctgcata accttgcccg
    34321 tcaccacagt gaatctacgc tggcgctggc cgataatctg gcgtcgctgt tggaaccggc
    34381 gttattgatc atcaccggct taattatcgg tacgctggtg gtggcgatgt atttgccgat
    34441 ttttcatttg ggagacgcga tgagcgggat gggataaggc tggcgcacat ttacgccagc
    34501 cagaatatta gaggctattg aaaatgcggt tttcttgttc ctgcacccga ataaaggtgg
    34561 tgcgtttggt caactctttc aggcgagacg cgccgacata agtgcaggct gagcgtagac
    34621 cgcccaggat atcgcgggcg gtattgccca ccggcccacg cagtggcaat ttaaccgttt
    34681 taccttctgc cgcgcggtat ttcgcaacgc cgccgacatg acggttcatc gcagattccg
    34741 aactcatgcc gtagaacagc atgaatttct cgccattctc ttctaccacg ctgccgccgc
    34801 tctcttcgtg acccgccagc ataccgccca acataacgaa atccgcgccg ccgccgaagg
    34861 cttttgctac gtcgcctggc atggtgcagc cgccatcgct gacgatcatg ccgcccaggc
    34921 catgcgccgc gtcagcacat tcgataaccg ccgacagttg cggataaccg acgccggttt
    34981 ttacacgcgt cgtgcatacg gagccgggac caattcccac tttcacgata tcggcgccgg
    35041 agaggataag ctcttcgcac atctcgcccg ttaccacatt gcctgcgcag attgtttttg
    35101 acggccatgc ttcacgcgct tttgcgacga actgcacaaa atgttctgaa tagccattgg
    35161 ccacatcaat acagacaaag ttcagcgcag gattcagcgc cagaatctgc acggtttttt
    35221 cgaaatcagc atcagaggtc ccggtggaaa ccatcacatg cttgagaaca tcagccgaag
    35281 ccgtgttgat aaaagctgcc cactcttcaa cgctataatg tttatgtaca gcggtcagaa
    35341 tatcaaaccc ggccaacgct tgcgccattt caaacgtccc gacggtatcc atattggccg
    35401 cgataatcgg tacgccagac caggtctgac ctgagtgttt aaaggtgaat tgacgttcca
    35461 gttcgacatc ggaacggctt ttgagggtag aacgcttagg acggataaga acgtctttga
    35521 aacctaactt cagatcttct tcaatacgca tgtgcggatt cctgaggtta atggcgaaaa
    35581 atcgaaactc acaactccag tgacgctatc atacgcacta atcatggccg tacaagactc
    35641 agaaattctc tttttttacg ttacaatccc ataaatttac ctggcgaata gtaggttaat
    35701 gctcagagca tatcgtcttt gtatgtttaa aatttaacct tttgattatc aaactaaaat
    35761 tccggaagct ggagatatga ggtataccgt agccttaacc ggcggtattg gcagcggtaa
    35821 aagtaccgtc gctgatgcct tcgctgacct cggaataacc gtcatcgacg cggatattat
    35881 cgcgcgccag atggttgagc cagggcagcc cgccctgaac gcaatagcgg aacattttgg
    35941 ttctgaactt atcgccgccg acggcacgtt acgtcgccgg gcactgcgtg agcgtatttt
    36001 ttcgcatccg gaagaaaaag cctggcttaa cgctctgctt catcccttaa ttcagcagga
    36061 aacccaacga cagtttcaac aggctacgtc gccctatgtg ttatgggttg tgcctctgct
    36121 ggttgaaaac aggttgtatc aaaaagccaa ccgcgtactg gtggttgacg ttacgcccga
    36181 aacgcagctc atacgcacaa tgcagcgtga tgatgttacg cgcgagcatg ttgaacacat
    36241 tctcgctgcg caggcgacgc gtgaagcgcg ccttgccgtg gcggacgatg ttattgataa
    36301 taacggcgca ccggatgcta tcgcatcaga tgtggcccgc ctgcacgcca gttatcttaa
    36361 gctcgcgtcg cagtttgtct cacaggaaaa accgtaatgc acacccaggt cctatttgaa
    36421 caccctctca atgagaagat gcgtacgtgg ctgcgcatag agtttttgat ccaacagctc
    36481 tccatcaacc tgccaattgc agaccatgct ggcgcactgc attttttccg taatatcagc
    36541 gatctactgg atgtgttcga acggggcgaa gtccgtaccg aactgctgaa agaactggag
    36601 cgccagcagc gtaaattaca ggcctgggtt gaggttcccg gcgtcgatca agaccgtatt
    36661 gaagccctgc gccagcagtt aaaatcggcg ggcagcgtgc tgatctccgc cccgaggatt
    36721 ggccagcagc tacgcgaaga tcgcttgatt gctcttgtgc gtcaacgctt aagtattcct
    36781 ggcggctgtt gcagtttcga tttacccact ctgcatatct ggttgcacct acaacaggcg
    36841 cagcgcgatg cccagattga aagctggctt gccagcctga atcccctcac ccaggcgctg
    36901 acgctggtgc ttgatctgat ccgtaattca gcgcctttcc gtaagcaaac cagcctgaac
    36961 ggtttttatc aggataacgg ggacgacgcc gatttgctgc gtcttatgct gacgctcgat
    37021 tcacaacttt atccgcaaat ttccggccat aagagccgtt ttgccattcg ctttatgccg
    37081 ctggatagtg aaaatggtct ggtgccggag cgtcttgatt ttgaactggc ctgttgctaa
    37141 ggagtaaaaa tgtctgacgt gaccgtcgta aactgtccga cctgcggtaa accggtcgtc
    37201 tggggggaaa ttagcccctt ccgcccattt tgttctaaac gctgtcagtt aattgatttg
    37261 ggcgaatggg ccgccgaaga gaaacgaatc gccagcagcg gcgaccagtc tgatagcgac
    37321 gactggagcg aagagcgcta acggtgatag ctctgttgag acggcaatat cgccttatga
    37381 caaaaataat caataaatac gcgtagtttt ggcgccatat gcgcgcggcc gggataatac
    37441 aaataaaacc ggtccgccgc aggcagccac tcctcaagta cggaacacaa ccgcccatcc
    37501 tgtaagtctt cgtggacatc ctgttcaaaa acgtaggtta gctctgcccc atcacgcgcg
    37561 gcggagagac gcaacgcttt atcattcacc attaacgcgg cttccggcgt aatttccagc
    37621 cgttgcgctc catgaacaaa ctcccaccga tatagcccgc tctcacgcgt aaaacgatgg
    37681 caaaggcagc ggtgattgat gagctcctga ggatgcagcg gcgtgccaaa acgcgcaagg
    37741 tatgcagggg atgctacgat cgccgggcgt aaaacatcac cgagcggaac gacattcata
    37801 tcaagttgta ccgcatcgcc aaagcgaata ccggcatcaa agcgttcgtt aattaaatcc
    37861 acaaaaccgt cattcacatc gatatccagc cgaatatcgg gataatcgcg catgaagccg
    37921 gcgagattag gttgtaacag aagcgtggcc gccgtgcgcg gtacggtcag gcgtaatgtc
    37981 cctccgggta tatcgcggct ctggcaggca tgttccatcg cctcatcaat atggttcaat
    38041 gcgggtctga tactggcaag aaaggcatgt cctgcttctg tcaaaccgac acgccgggtg
    38101 gttcggttca ataatttcac gccaagttca tcctccagtt gacgcatatt ctgacttaac
    38161 gccgacgtgg aaatatgtaa ctgcgccgct gcccgcgtga agctatggtt ttcagcaatc
    38221 atgcaaaaag catgcaatac ggacatcaca tcatgacgca ttattaagcc agccttcata
    38281 aaccatgctt attcccccta tttttcatct tatacgccag gtatagactg cctgccatgc
    38341 acaaaatatc ctcatggagg cagtatgcaa tatcgtacat taggcgcaaa cggaccgcga
    38401 gtgtcagcca tcggactggg atgtatgggc atgagcgcat tttacggcgc tcatgacgac
    38461 agcacctcaa ttaagacgct acattatgcg ttagatcagg gggtaacact gctcgatacc
    38521 gcagatatgt atggccctta taccaatgaa aggttagtcg gaagagccat cgccgatcgt
    38581 cgcgatcggg tatttttagc gacgaaattt ggtatcgttc tcgaccctgc taaccctatg
    38641 gcgcgtggcg tcaatggcag accggagtac gttcgccgta gttgtgagca aagcctgcaa
    38701 cgcctggggg tcgatcatat cgatctgtac tatcaacatc gcgttgatcc atcagttccc
    38761 atagaagaga ctgtcggtgc aatggcggac ctggtgcgcg agggaaaagt gcgttatctc
    38821 gggctatccg aagcatcaac gcaaacgctg gaacgcgccc ataacgttca ccctattacc
    38881 gcgctgcaaa gtgagtattc gctttggtcc cgcgaagcgg aaatttcagc actttccacc
    38941 tgtgaacggt tgggtatagg attcgtcgct tacagcccgc tgggacgcgg atttctgacc
    39001 ggtacgatta aaacgccaga agattttgct gcgaatgact tccgtcgcac aaatcccaga
    39061 ttcatgggtg agaacttctc gcgcaattta cgtctggctg aagcaataaa acaaatggca
    39121 cgcgaaaaag agtgtacccc cgcacaatta gcgctggcct ggctgctggc ccgcaacagg
    39181 cacctcgttc ccattcccgg cacccgccac tgcgccaggg tggatgaaaa cctcggcgcg
    39241 ttatcactga ccctaagccc gcaggagctg gcggcaattg aggcggtttt tcctcacgac
    39301 gccgcagccg gcccccgcta ctggccggaa attatgtcga cattaaatcg ctaataagat
    39361 cgatggggat cgtgttgcga tcccccacta aggcgcaaat tggcgtaatt tacgaataat
    39421 cggttcattg gccggcggaa aatcgtccgt attcaacgcg ttttgcgcga tccaccgtcc
    39481 cggctgtcct tctttccccc acggttcgcc ctcccagcgt tcaaccagcc aaaaccacag
    39541 cgtaatgtgt ctatccggga attgatattc cagagtgtcg aataatgtca cctgtgttgg
    39601 cgtaatcccc acctcttcct gtagctcccg gatcaacgcc tgctctggtg tttcgccggc
    39661 ttcaattttt ccgccgggaa attccagctt gttcgccata tgcgcatcag cggcgcgtcg
    39721 ggtaataaaa atttcgtcgt tcgggttgcg gataatccca accgcgattt gcagtttttt
    39781 catcttggtg catccataaa aaaggcgcag tcgcctgcgc ctttttatct gtgttcaatg
    39841 ctaggccgaa taagcgtagc gcccttcggc aataatgcca gcaccgaccg acctgatggc
    39901 aacacattat gtcttatcag gccggtaagt ttatcgcatc agctcaggcg accgtgacac
    39961 tgtttgtatt tcttaccgga accacaaggg caaggatcgt tacgtccaat cttacgttcg
    40021 ccggtttggg cggccagatc ggcagccacg gcggcatcgt catcctgatg gcttagctgc
    40081 tgcatctgcg ccaagcgctc cgcctcttcg cgacgctgca tttccatcgc ttcgacctct
    40141 tccggcatac gtacctggac tttgctcagg gtactgatca cttcatattt cagcgattcc
    40201 agcatcgcgg cgaacatagc gaaggattcg cgcttgtatt cctgcttcgg atctttttgc
    40261 gcatagccgc gcagatgaat accctgacgc aggtaatcca tcgccgccaa atgctctttc
    40321 cacagggaat cgagcgtttg cagcatcacg cctttttcga aatgacgcat catttcagcg
    40381 ccaaccacct cttctttacg ctgatacacc tcgatggact gcgccaggat gcgctcacgc
    40441 agcgtctcct catgcagctc cggctcttta tccagccatt cggcaatcgg catctccagg
    40501 tcgaagtcgt ttttcaggcg ttcctgcaaa cccgggatat cccacatctc ttccagcgac
    40561 tgcggcggaa tgtaggcgtc gatagtcgcc ttaaagacat cttcgcgaat gctgttaatg
    40621 gtgtcgctca cgtcagacac atccagcagt tcgttacgct gggtataaat tgcacggcgc
    40681 tgatcgttcg ccacatcatc atattccagc agttgcttac gaatatcgaa gttacggctt
    40741 tctactttac gctgcgcgtt agcgatagct ttcgtcaccc acgggtgctc aatcgcttcg
    40801 cccggcttca ttcccagttt acgcatcata ccggagacac gatcggaggc gaaaatacgc
    40861 atcagcgcat cttccatcga caggtagaaa cgggaagaac ccggatcgcc ctggcgaccg
    40921 gaacggccac gcagctggtt gtcgatacgg cgggattcat ggcgctcggt gccaatgata
    40981 tgcaggccgc cggcagccag aaccgcgtca tggcgtacct gccagtccgc tttaatctgc
    41041 gcaatctgtt cttccgtcgg cgcttccagc gcagcgactt ccgcctgcca gctaccgccc
    41101 agcataatat cggtaccacg acccgccatg ttggtagcga tagtgaccgc cgctggataa
    41161 ccagcctgcg caacgatgcc tgcttcgttg gcgtggaatt ttgcgttcag tacgttatgt
    41221 ttgatgcccg ctttggtcag ctctctggag accacttcag atttctcgat agaaatcgtc
    41281 ccgaccagca ctggctgacc gttcgcggta cgttctttaa tatcttcgat aatggcctgg
    41341 attttttccg cttcggttat gtagaccaga tccggcaaat ctttacggat catcggacgg
    41401 ttggtcggaa caacgacggt gtccagctta tagatagaac taaattcgaa ggcttcagta
    41461 tccgccgtac cggtcatacc ggccagcttt tcatacagac ggaagtagtt ctggaaggta
    41521 atagacgcca gcgtctggtt ttcattctga atttcaacgc cttctttcgc ttctaccgcc
    41581 tggtgcagac cgtcagacca gcgacgcccc tgcatggtac gaccggtatg ttcatcaaca
    41641 atgatgactt cgccgtcttt cacaatgtaa tccacgtcac gggtaaacag cgcgtgcgcg
    41701 cgcagcgcgg cggtgacgtg atgcatcaac ataatattgc caggcgagta gagcgactcg
    41761 ccttcatcca taatgccttc ttgcaccagt agctcttcga tcagcaccag accgcgttcg
    41821 gtcaggttaa cctggcgcgc tttctcatca acggagaagt ggccttcgcc ctggaaagtg
    41881 tcagaatctt ctttctcctg acgaatcagg tgcggaatga ttttgttcac ttttttgtac
    41941 atttccgagc tatcttccgc cgggccggaa ataatcagcg gcgtacgcgc ttcatcgatc
    42001 aggatggagt caacctcatc caccagcgca taatgcagtt tacgctgcac gcgctcttcc
    42061 gggctgaacg ccatgttgtc gcgcaggtag tcaaaaccgt attcgttgtt agtgccgtaa
    42121 gtgatgtcgg cagcgtaagc ttcacgtttg gctggcgcag gcatacctgg caggttgata
    42181 ccaacggaca taccgaggaa ttcgaatagc ggacggttgt tttcggcgtc acgctgcgcc
    42241 agatagtcgt tcacggtcac cacatgaacg cctttgccgg acagcgcgtt caggtaggct
    42301 ggcagggttg cggtcagcgt cttaccttca ccagtacgca tttcggcaat acaacgatcg
    42361 ttgagcacca tgccacccaa tagctgaacg tcgaagtgac gcatcccaaa gacgcgttta
    42421 ctggcttcac gcaccaccgc gaacgcttcc ggaatcaggc tctctacgct ttcgcctttt
    42481 ccaatacggg cgcgaaattc gttggttttc gctttcagtt cgtcatcgga gagtttttcc
    42541 atctccggtt ccatcgcatt aataaggctg acggccttac gcatacgacg cagcgtacga
    42601 tcgttacggc taccgaatac tttggttaat aatttgatta gcataataaa gtctcaaatg
    42661 ccccgcgccg cggagctaca aataaagtaa aagggtcttt tttcgttagc tgagacgttg
    42721 cggaccggcg cggataccct gcgcctgact tatccaggcc gggatgctaa atgcggtttg
    42781 tggcgcaaaa tacgccaggg agaggcggcg aacaatcgcc ggcggcgtgc cctcctgcgt
    42841 gagcatcgcg ctgagcgtat tcagtaaggc gatatgatgc gcctgtaatg gcgacggcgc
    42901 gtcggcaacg ggcagcgttt gcggcgccat tgcaaaagaa aggtggcgaa tcaccgtgcg
    42961 aatagcgtgc tgatgccagt aatctacggt gaaattggga cgacggttag aggcttctaa
    43021 cagcgcaaga tggctaaagt taactttaga cgcggtgctg gcggtcgtcc ttgcaggcgt
    43081 attggtttca gcggcgttac tgagcgcggg caaaccaaaa ctcgccgcga ccatccctaa
    43141 taagagatgc ggccagaagt atcgtctgcc taactgtcgc cagcgcgtca gtattccact
    43201 cacgtcattg ccacctgata tgcccctcat gggcttacgg aatcaaaaca atttgcgcac
    43261 aaatcttatc attaaagcgt acgcgctaca gcagtaatga cgagaagcta aggtgaaaat
    43321 cggctaagaa aacagcgaac gcgccgtgtt tccatttaac cctgtcaaaa tggctgtatt
    43381 aaggaaagcg cagataaagg atagtaaaaa aaaaaacgac tagctcgcct ggccggagag
    43441 agtgccaggt taaccagtcg aattttatac gacagcgtat gtcgttatgc cagtaccgtc
    43501 gaaggcgctt tgaaagccaa cggcagttct gcgtcgtcct ggaaggtcac aaattcccag
    43561 gcttcctgtt ttgccaggac tgcctgtaac aatttgttat tcaatgcgtg accggattta
    43621 tacgcggtaa acgcaccaat aatattgtga ccacacatga acaagtcacc gatcgcgtcg
    43681 agcattttgt gacgaacgaa ttcatcttca aaacgcaggc cgtcttcgtt caatacgcga
    43741 taatcgtcaa caacgatggc acaatcgaag ctgccgccca ggcacaggcc gcgggactgc
    43801 agatattcga tatcacgcat aaaaccgaag gtacgcgcac ggctgatctg gcgcatgaac
    43861 gcatccgcag agaagttcat cgcgtagcgc tggctgctgg aatcgatcgc cggatggtta
    43921 aagtcgatgg tgaaatccaa cgtaaaacca ttgtacggtc tgaattcagc ccatttatcg
    43981 ccatcttcaa cccgaacagt ctctttgatg cgtacgaatt ttttggcgca gttcagtgca
    44041 tcaataccgg catcaagcag caggtagaca aacggagcgg cactgccatc catgatcggg
    44101 atttccgggg cattaacctc aataacgatg ttatcgatac ctaagcccgc cagagcagcg
    44161 ttcaggtgct caacggttga aatccgtaca tcatgctcat tcaccagaca cgtacagagc
    44221 atggtatcac gcacagattt ggcatcggcc gggaaatcta ccggtggatt caagtcggtg
    44281 cgacgataga tgaccccggt attggccggc gcagggcgta atgtcagggt gacttttttg
    44341 ccggtgtgta aaccgacgcc agtcgcctga acgatacgtt taagtgtcct ttgtttgatc
    44401 atcgtataat ctcgccaaat tacctatcca accgaagtgt actatacatt cggcgggcca
    44461 gtttagcaca aagagcccag aatcccaaat tccagctaat tcttaatcag cttgcttacg
    44521 caggaatgcg gggatatcca gataatccgg ctctttcgcc gcctgtggcg cattgtcgtt
    44581 aaccactttc gcgaccgttt tttgctcctg cgtcagcggc gccataccgt gctgctgata
    44641 acgatccaac accggctgct gcacctgttt attggtgacc agagtgattt caggacgctt
    44701 gtccatacca attccagtgg caacaacggt cacgcgcagt tcgtcgttca tatccgggtc
    44761 cagagaggta ccgataacca cggtggcgtt atccgacgca aaggcacgga tggtgttacc
    44821 gacggtttcg aactcatcca gacgcaggtc gaagcccgcc gtaatgttga ccaacacgcc
    44881 gcgcgcgccg gacaggtcga tatcttccag cagcggagaa gaaatagcca tttcagccgc
    44941 ttcttccgca cggtcttcac cgctcgccac gccggagccc atcattgcgt agcccatttc
    45001 agacatcacg gtacgcacgt cagcaaagtc gacgttcatc aggcccgggc gggtgatcag
    45061 ctctgcgata ccctgaaccg cgcctttcag cacgtcgtta gccgcgccga acgcgtcgag
    45121 cagggagatg ccacggccca gcactttcag cagcttgtcg ttcgggatgg tgatcaacga
    45181 gtccacatgc ttggacagct cggtgatacc ctgctccgca aatgccatgc gctttttgcc
    45241 ttcaaaattg aaaggcttag tcaccacggc aacggtcaga atacctaaat cttttgccac
    45301 ttcagcaacc actggcgccg cgccggttcc ggtaccgccg cccatgcctg ccgcgataaa
    45361 taccatgtct gcgccttcaa gcgccgcacg cagcgcttca cggtcttcgt ccgccgcatt
    45421 acggccgact tccgggttag cgccggcgcc cagacctttg gtaatgccgc taccaatttg
    45481 aatggtctgg ccaaccgccg tcttacgcaa cgcctgcgcg tcggtattca ccgcgaagaa
    45541 ttcaacacct tcgatgcgct cgcgcaccat gtgttcaaca gcgttaccgc cgccaccacc
    45601 gacgccgatg actgtaatca ccgcgtcgtt ggttagttcc ataggttcaa acataatctc
    45661 tctccgtcat gtgcctgtcg cctgaggccg taatatctgg cggcctcata aaaattaaaa
    45721 ctcttttcgc agccagctat taagtcgctt gatccacgag ccaactgatg ccgtaacacg
    45781 tttttccact tctgcttcac cgtttaagtg ggactctttc ccgtagtgaa gcaatcccac
    45841 cgccgttgag taatacggct cctgggcata atccgtcaga ccggtgatat tcagcggcgc
    45901 gccgatacgc acctgcgtat gaaacacgcg ctgagcgcaa gcagcaagcc cttcgatttg
    45961 cgccgcgccg ccggttaaca caatgcccgc cgccaggtga tgttttaccc cttgttggcg
    46021 aagctgttcc tgtaattgca atatctcttc gttgaccaga ttgagcagct cggtgtaacg
    46081 cggctcaatc acttccgcca gcgtctgacg ttgcaggctg cgcggcggac gcccgcctac
    46141 gctcggtact tcaacgcttt cgtctttacc gacaatggaa cccagcgcgc aaccgtggcg
    46201 aactttaatg gcttcagcat cgctcggcgg cgtaccaaag gcataagcga tatcgctggt
    46261 caccacgttc cccgcgtaag ggatcacttt ggtatgacgc agcgcgccgc cagtataaac
    46321 ggcgatatcc attgtaccac cgccgatatc cacgacacag acgcccagtt cacgttcatc
    46381 ttccgttaac acggaataac tggccgccag tccggcaaat atcagttggt caactttcag
    46441 accacaacgt tcaacagctt tgacaatgtt ttttgccata tcgttgtggc aggtaatcaa
    46501 atgtactttc gcctgcatac gcacgccgga aagaccgacc ggatttttaa tgccttcctg
    46561 gtagtcaatg gcgtactcct gaggaatcac atgcagcacg cgatgttcat cgcgcacgcg
    46621 cactgacttc gcagtatgca cgacgttttc cacatcttcc tgcgtcactt cctcttcgga
    46681 aatgggcacc ataccaattt cattctgaca gctaatatgt ttgccggaaa gcgccagata
    46741 taccgaggag atctggcaat cagccatcaa ttccgcctgg tcaatggcgc gctgaacgca
    46801 tttcaccact gactcaaggt cattcacccc gcctttatcc ataccccgcg atgggcaact
    46861 gcccacgcca atgatattga ccataccgtc gggcagaact tcccctacta aagcggcaac
    46921 cttcgcggtg ccaatctcca gtcctactac cagttttctg tccgtcgcct tgatcattgt
    46981 tgttctgcct gtgcctgatt ctgttgctga ttagattcct caggggggag cggcgcccag
    47041 ccaactgccg cacctgagtc ataacgcaaa tcaacgtagc taatccgttt gccatcggtt
    47101 tgcgcctgct gctgtaaaac cggatagagt tctacaaagc gagccaacct tttcatcgta
    47161 tcgcccctgc cgagattgag cttaatgccg ttattaagcg tcaattgcca ggagcgacgt
    47221 gcggtcatcg ccgcttcctt tagagtgaat ttatccttag ccagcacctg ccccatctcg
    47281 cggtatccct gcaacacttc actcgcgctg ccttccgggc cgtacaacat gggtaaaacc
    47341 tgtttgccga tgcggtctga cggcacgctg aaggtgttcc cttcagcatc gaccatatgt
    47401 tgatcattcc aacgcgcaat cggcacatat tcaaccagat gaatcttcaa ttcatcaggc
    47461 cactgttttc tgacgctggc ctgtttaatc cacggcaaac gctcaatctg gctctggata
    47521 atgttcacat cctgcgtcat gaaggttccc ggcgcgccca gagccagtat cgcctgacgg
    47581 atatcatcgt tacgcgtgta gtgacgctcg ccggttaata ccagctttga taacggtaaa
    47641 cgctgcgcat cttccatcca ccctaacacg acccacccgc taacaaacac ggtgcacagt
    47701 accgtcagca ggaataatat tcctgcaaga cgcgttccat tattgcggcg tgaagaaggc
    47761 gtctcttcat cactgtttcg cgtgttcagc gcagcctgcg acatatcagt ccgccaactc
    47821 cagaattcgt accactaact gcgagaagct cattcccgcc tgacgcgccg ccatcggcac
    47881 cagactatgg ctggtcatcc ccggagaagt attggcttcc agcagataaa actgaccatc
    47941 gctgtccagc atgacgtcaa tacgccccca tcccgtgcag cctaaagctt tccatgcctg
    48001 caggacgaga gactgtagcg cggcttcctg ggacgcttct aaaccggcag ggcagaaata
    48061 ctgagtctca tcagagagat acttcgcctc ataatcatag aaggttcctg ccggttggat
    48121 acgaattgac ggtaaaattt cttcgccaac tatcgccacc gtaaattccg gaccgcacag
    48181 ccatttctca atcagtattt cgtcatcatg ctgaaaagcc aatgataacg caccctgtaa
    48241 agcattttct tctactactt tcgtcatacc gacgctggag ccttcacggc tgggtttgac
    48301 gatcagcggt aaacccagcg ccgaaattcg cgctttttgt tcttcgctaa ggcctttttc
    48361 aaactcagcg cgcgtcagcg cgacccacgg cgcaaccggt aagcctgcgc cctgccacag
    48421 caatttactg cgcagtttat ccatggaaag cgccgaggcc atcacgccgc tgccggtata
    48481 aggcaggccg agcagttcaa gcattccctg taaggtgcca tcttcaccgc cgcggccatg
    48541 caacgcaata aagaccttct gaaagcccat tgctttaagc tgcgcgacat cgacctcttg
    48601 cggatcgacg ggatgcgcat caataccgcc ttcacgtaac ccggccaaca ctgccgcgcc
    48661 ggaatttaac gaaacgtccc gctccgcaga ggttccgccc aacaggaccg cgattttatc
    48721 agccatgttg ctcttcctcc tggatttgcg gcttcagctt gatttcagat aagtaacgcg
    48781 caattttgcc aacatttcct gcgccttgca ctaatatcaa gtcgttaccc gtcagcaccg
    48841 gcgctaacat tgtcgcaacc tgagccggat cggaaaccag aatcgggtca atttttcccc
    48901 gattacgaat cgtgcgacat aaagaacggc tatccgcgcc cggaatcggc gcttcgcccg
    48961 ccgggtaaac gtccagcatc agcagcgcat cgacctgggt cagcacattg gcgaaatcgt
    49021 catacagatc gcgcgtgcgc gtgtaacgat gcggctgaaa cagcatcacc aggtttttat
    49081 ccggccaccc tgctcgcgca gctttaatgg tggcgtccac ttcggtcgga tgatgtccat
    49141 agtcatccac cagcatcgcc gtcccggctt taccattcac cggctcaagc gggaactcgc
    49201 cgaggaagtc aaaacgacgc ccggtcccct ggaagctttc cagcgcgcgc aggatagcgt
    49261 catcgtcgat gccttcttcg gtcgctaccg ccactgccgc ggcggcattc agggcattgt
    49321 ggcgacccgg cgcattcaac gtgacatgca gatccggcat tccctggcgc aacagcgtaa
    49381 agtgcccctg cggccctatc tgctgataat cttctacgcg gacgtcagca tcctcgctaa
    49441 agccatacgt cgtggtctga cgccccaccc gcggcagcaa ctcgcggatg accggatcgt
    49501 cgacgcacat taccgcgcga ccgtagaacg gcaggttatg caggaagtta ataaacgtct
    49561 gctttaaatt ttcaaagtcg ccatgatagg tatccatatg gtcggcttcg atgttggtga
    49621 cgatcgcaac catcggctgc aaatgcagga aggatgcgtc gctctcatct gcctcggcaa
    49681 tcaggtaacg actatggccc agacgcgcat gaacgcctgc ggctttcacc aatccgccat
    49741 tcacgaaagt cgggtccagc cccgcttcgg cataaatact ggacaccatc gcggtcgttg
    49801 tggtttttcc gtgcgtcccg gcaatggcga tgccgtggcg aaaacgcatc agttccgcca
    49861 gcatttccgc acggcgaata accggaatac gcgcttcatg cgccgcgaca atttccgggt
    49921 tatccgcgga aattgcgctg gaaacgacga ccacgctggc atcacgcaca ttttccggac
    49981 gatggttaaa gaaaatcgtc gcccccaggc tcgtcaactg ctgggtcacc ggattcggcg
    50041 ctaaatcgga accactgatc tgataccctt cattggccag aacttcggca ataccgccca
    50101 taccagcacc accgatgccg acaaagtgaa tgtgccgaac gcgacgcatt tcgggcacga
    50161 tggaacgcag ttttgccagt tgttgtgtat tcattcttta cgccattaac tccaataccc
    50221 gccatacttc aaattgcaga tgcgttggct tgcctgcaac ccaaattatt gagggtagaa
    50281 aaaccctgcg atgcaaaagg caccgccaca aattatgtcc gggcaacccg gctgacttca
    50341 ctggcgacgc gctcggtagc atccggaatg gataccgcgc gggcacgctc cgccatggtt
    50401 aacaacgcct cgcgcgacca ccccgccagg gtgtcggcga cagcctctac agtaaactgc
    50461 ggctgctcaa aaatcttagc tgcgccggcg ttttctaacg gcagcgcatt ccagtactgc
    50521 tgcctgtctt tatgctgaaa cggcacgaat atcgccggta acccggcggc ggcgatctcg
    50581 ctcaccgtta aagcgccgga acgacatacc accacatccg cccacgcata ggcggcggcc
    50641 atgccatcga taaattccgt taccttatgc tgcggttgtc ccgccccggc atatgcctgc
    50701 tctaccgtga gctgcgcgcc ttttccgctt tgatgccaga ttgtaaccgt atcgcccagt
    50761 ctggcggcaa cctgcggcat cgtctggttc aggactcgcg ccccctgaga accgccgacc
    50821 accaacacgc gaatcgggcc gtcacgaccg gccagacgca cctgcggcaa cggcaacgcc
    50881 agtacgtcgg tacgcaccgg gttacccacc acttccgcgt tcgggaacgc accgggaaac
    50941 gcctgcatca ccgtggtcgc gattttggcc agccactgat tggttagccc ggcgataccg
    51001 ttttgctcat gcaaaacgac cggaataccc aatgaccagg cggcaagacc gccggggccg
    51061 gaaacataac cgcccattcc cagcacgaca tccggcttaa accgcttcat gatcgcccgc
    51121 gcctgccgcc aggcgttaaa aatccgcagc ggcgccgcca gaagcgcttt tacgccttta
    51181 ccgcgcagac cggagatccg aataaagtca atatcgatgc catgcttcgg cactaaatcc
    51241 gcttccatac gatcggaggt acccagccag cgaacctgcc agccctgggc cattaaatga
    51301 tgcgcaacgg ccagtccggg gaacacgtgc ccgccggtac cgcccgccat caccattaac
    51361 cgcttcggtt gaccactcat cgagaacctc gtgtaaacgc ctgcgctttt tccagacgcg
    51421 tttcataatc aatacgtaat aaaaacataa tggccgtcga cataatcaac agactcgacc
    51481 cgccataact gatcagcggc agcgtaagac ctttggtcgg cagcatcccc gcggccgcgc
    51541 caacgtttac cagcgcctga aaactaaacc agataccgat agaacacgct aaaaatccgg
    51601 aaaaacggtg gtcaatctcc aatgccttac ggccaatcga catcgcgcga aaagcgacga
    51661 aaaataccat taaaagcgcc aataccacac cgatataacc cagttcttcc ccaataatgg
    51721 cgaagatgaa atcggtgtgc gcctccggca aatactccag tttctgcacc gaattcccca
    51781 gcccttgccc ccatatctca ccgcgaccaa aagccatcag cgactgcgtc agctgataac
    51841 cgctgccgaa cggatcttcc caggggttcc agaacgaggt aacgcggcga atacgatacg
    51901 gttcggcgag gattaacaga atcaccgccg agatgcccat cccgataatg gcgatgaact
    51961 gccataattt cgccccggca agaaacagca tcgccagcgt ggtgacaaac agtacgacca
    52021 ccgtcccgag gtcaggctgt gccagcagta acaccgccag caccagaatc acgcccattg
    52081 gttttaaaaa gccgcgcagg ttatttcgca cttcatcaac cttacgcacc agatagttcg
    52141 cgaggtagca gaacagcgac agcttggtaa actccgcagg ctgaatacgc agcggcccca
    52201 gcgcaatcca gcgcgacgcc ccgttaaccg agctcccgac gaccagcacg ataagcagca
    52261 taatgatcga cgcaatcagc atcgtcgtgc tgtatttttg ccagaaggtc atgggcaaac
    52321 gtagcgtgac catcgccaga caaaatgcca ggaagatata gagcgcatca cgtttggcaa
    52381 acaaaaacgg atcgttcgcc aggcgctgcc cgactggcat ggaggccgac gtcaccatga
    52441 caaaaccaat cgccgccagc ccgaaggtca gccatagcag cgtgcggtca tacatgatca
    52501 gactgtcggc gtctttatcg cgcgaagcca tcacccagcc tttaagcgcc gcaaacagcc
    52561 aggccaggag gccaaagcct ggtacgcgcg gcattctcag acgggggaga gataaacgca
    52621 tcaacctaac tccttcgcca gacgggtaaa gacatcgccc cgttgctcaa aatttttaaa
    52681 ctgatcgagg ctggcgcagg cgggcgacaa cagcaccata tcacccggct gaacgtgcgg
    52741 cgccagcaaa cgcatcgcct cttccatcgt ctcagtctgt tgggcgattt ccggacgcag
    52801 tgcggcaagc tgcgcgccat cgcgcccaaa gcaatacagg cggatacgat cgccggtcag
    52861 atagcgcgcc agcggagaaa agtctgccga cttaccgtcg ccgcccagca gcagatgcag
    52921 cgtaccgtcc acatgcaaac cgtttagcgc cgcttcggta ctgccgacat tggtcgcttt
    52981 cgagtcgttg atccaacgaa cgccgttatg ctccaacgcc agctggaagc gatgcgccag
    53041 accggtaaat gtcgtcaacg ccttcaaact gctggcgcgc ggcagaccta cggcatccgc
    53101 cagcgccagc gccgctaacg cattggtata gttatgctga ccggaaagct tcatctcttt
    53161 cacgttcagc accttctcac ctttgactcg tagccaggtt tcgccctgct gacgattaag
    53221 gtgataatca cccatattga cgccaaagct gacgcagcgc tcatcggccc cgcgtaccgg
    53281 catcgtcaac gcgtcatcgg cattcactac gcacactttc gccttctcgt agacgcgcag
    53341 tttcgccgcc cggtactgtt gcaaaccaaa cggataccgg tccatatgat cttcagtgac
    53401 gttgagcacc gttgccgccg ccgcttgcaa acttgaggta gtttccaatt ggaaactgga
    53461 taattccagc acgtacaatt cgcgatcggc atccagcagc atcagcgccg gaagaccgat
    53521 attgccgcca acgccgacat tgacgcccgc cgccttcgcc atctcgccca ctaaggtggt
    53581 cacggtgctt ttgccgttcg agccggtgat ggccacaatc ggcgcttgcg cttcgcggca
    53641 aaacagttcg atatcgccga caatttccac tccagcgctg gcggcagcgc taagagaggg
    53701 atgcgccaga gcaataccag ggctggcgac gattaaatcc gccgctaaga gccactcgtc
    53761 gttcaggccg ccaacgtgac gctcaacctc ttgcggcagc ttatccagac ccggcggcgt
    53821 cacgcgagta tccatcaccc gcggcgtcac gccgcgggcg agaaaaaagt ccacgcaaga
    53881 gagtccggtt aagcccagac cgataatgac gacgtttttg tcctggtaat cagccatgat
    53941 taacgtacct tcagcgttgc caggccaatc agcaccagca tcagcgaaat aatccagaag
    54001 cgcacaatca cgcgcggttc cggccagcct ttcagttcat agtggtgatg gataggcgcc
    54061 atacggaaaa tacgctgtcc gcgtagttta aaggaaccca cctgcaggat gaccgacaga
    54121 gtttccacca caaagacgcc gcccatgatc accagcagaa attcctgacg cagcagcacg
    54181 gcgataatgc ccaacgcgcc gcccaacgcc agcgatccga catcgcccat aaaaacctgc
    54241 gccggatagg tgttaaacca caagaatcct aatcccgcgc cgacaatcgc cgtacagaca
    54301 atcaccagct cgcccgcatg gcgtaaatac ggaatatgca ggtaattggc gaagttcatg
    54361 ttcccggtcg cccaagccac cagcgcaaag ccggcggcaa cgaagacagt cggcataatc
    54421 gccagaccat caagcccgtc ggtcaggttt acggcgttac ccgtaccgac gatgacaaag
    54481 taggacagca gaatgtaaaa cagccccaat tgcggcataa catctttaaa gaacggcacc
    54541 accagttggg tcgcgggcgt gtctttcccg acgagataaa gcgcaaaggc cacgccgagc
    54601 gcgataaccg acatccagaa atatttccag cgcgcaatca gccctttggt atctttccgc
    54661 accactttgc ggtagtcatc gacaaaaccg ataatgccgt agccgatcaa taccaccagc
    54721 acgcaccaga cgtacgggtt agacgggtaa gcccataaca gaacggaaat cacaatcgcc
    54781 gtcaggatca tgatgccgcc catcgtcggc gtaccgcgtt tactgaagtg cgattccggg
    54841 ccatcgttac gtaccacctg gccaaaagag agtttttgca gacgagcgat catacgcggg
    54901 cccatccata aagagatgaa cagcgcggtc aacaggctga cgatggcgcg aaacgtcaga
    54961 taagaaaaga cgttaaagcc ggaataatat ttgaccaaat gctcggccag ccaaactaac
    55021 atgaaccttt ctcctgtaac gcatgaacca catcttccat cgcggcgctg cgtgatcctt
    55081 tcactaaaat agtcatcatc ggttgctcct gaagcagagc gtgtaaacgc gcaatgagcg
    55141 cggctttatc ggcaaaatgt tcgccgacgc cgctggcgtg gctgataacc tgactgagtt
    55201 ttccggtgct taacacgcga tcaatacccg ccgcttttgc ggcctcgcca acctggaggt
    55261 ggcacgcttc gctttctgcg cccagctcgg ccatatcgcc taccaccagc acgcggtagc
    55321 cgggcatttc agaaaggacc tgcactgcgg cggtcatcga accgacgttg gcgttataag
    55381 cgtcatccag taccagttgg ttttcactta gttgaatcgg gaacagacgc ccgggtacgg
    55441 cttttaacgc cgccagccct gctttaaccg ccgccagcgt cgcccccacc gccattgata
    55501 aagcagcggc cgccagcgcg ttggcaatat tgtgccgccc cggcaacggc agcagcacat
    55561 caatgctgcc catcggcgtt tgcagggtaa attcggtacc gtgtgacgtc acgtggatat
    55621 tcgcagcggt aaagtcgctg tttgccgcat tcggcgaaaa gcgccacacc tgacgatcgc
    55681 caataatgct ttgccagttc agccagtcat tattatcggc attcataatc gcgataccgt
    55741 tctcaggcaa accggtatag atttcgcctt tcgctttcgc cacgccggcc agcgagccga
    55801 aaccttccag atgcgccgcc gccaggttat tgaccagcgc cgcttccggg cgcgtcaggc
    55861 taacggtcca ggcgatttct ccctggtgat tagcgcctaa ctcgatcacc gcatagtcat
    55921 aatcatggtt taagcgcagc agcgttatcg gcacgccgat gtcgttgtta aaattgcttg
    55981 cggtatacaa agtatttccg cactggctaa gaatcgcggc ggtcatctct ttgaccgagg
    56041 ttttgccgga cgaaccggtt aacgccacca cccgcgccgg tacctgcata cgtacccagg
    56101 cggccagttg gccaaatgcc tgacgcgtgt cttttacaat cacctgcgga agatcgatat
    56161 ccagaggacg actgaccagc agggcgccag cgccgttcgc ttttgcttta tcagcaaaat
    56221 catgcgcatc aaagcgttcc cctttcagcg ccacgaacag gcatcccggc gtcactttcc
    56281 gtgtgtcggt aatgaccgta tcgagcgtga gatccgcccc gcggtgttcg gcgccaagga
    56341 catcggcaat tttgctgagc gttacgctaa tcatgcgatc acccccagca aacgcgctgc
    56401 ggtcacgcgg tctgaataat caagacgctg cgtgccgaca atctggtaat cctcgtgccc
    56461 tttacctgca atcagcacga cgtcattgtc ttttgcctgc ataatggcat tggttaccgc
    56521 ctcagcgcgg ccttccatta ccctgacctg cccggcgtcc agcattccgg ccagaatatc
    56581 gttgataatg gcgcgcggct cctcggtacg cgggttatcg tcagtcacca cgacgatatc
    56641 cgcgaattct tcggcaatgg cccccatgag tgggcgctta cctttgtcac gatccccgcc
    56701 acagccaaag acgcaccaca attttccggc gcagtgcagg cgcgccgcct gcaatgcttt
    56761 ttccagcgca tccggcgtgt gcgcgtaatc caccaccacc gtcggtttgc ctggcgcagt
    56821 gaacacttcc atacgcccgc aaaccggctg caaacgcgcg gcggttttca gcaaatccgt
    56881 taacggatag cccagcgcca gcagcgtcgc caatgccagc agtaagttgc tgacgttaaa
    56941 cgcgcccatc aggcagcttt cgatttcgcc ttcaccccag cttgaagcaa aacgaatcgt
    57001 cactccgcgg tcgtggtact ccaccgcctc cgctttcagc caacgaccgt gacagttagg
    57061 gttgatatgc ccttccattg aaaccgcgac cgcatcgggt agcgacgcca gccagcggcg
    57121 tccaacttca tcatcggcgt tgacgattgc ctgaccgtga tggtgggtgg aataaagcat
    57181 ccattttgcc gcctcgtaat gcgccatatc gccatgatag tcgagatggt cgcggctcaa
    57241 attagtaaac acggaggcgg caaatttcag cgccgccacg cgatgctgca ccaggccgtg
    57301 agaagagact tccatagcgc cgaaggtcgc gccctgcgca accagactgg ccagcacatg
    57361 ctgaacatcc actgcggaac cggttgtgtt ctccgtcggg atcactttac ccaacagtcc
    57421 gttacctacc gtccccatca ctgcgctggt ttcgccgagc aactggctcc actgcgccag
    57481 tagttgggtg gtggtggtct tgccattggt gccggtcacc gccaccagac gcatgttttc
    57541 agatggctca tggtaaaagc ggcccgccag cgcagataaa cgctcattga gctggctgag
    57601 atagacgact ggtacgccgt gcatttcgcg aatctcaccg tcactcgcct cgtctttcgc
    57661 ctctgcaata atggcagcta cgccttgcgc tatcgcctgc gggatataac gacgcccgtc
    57721 cgcctgatga cccaccactg ccacaaagag atcgcccgcc gcagccacac ggctgtcgag
    57781 cgtcatctct cgcagttctc gcgcgggtag tccagccacc cacggagcaa gaaggtcgcg
    57841 caaattacga tctgccacct gttccctcgc cttgattaat tacgaattca tttttttcgc
    57901 ccgttgccag cgcgtccggt tcgatgttca tggtgcgcag aacgccgccc atgatggcac
    57961 caaataccgg cgcggaaacg gcgccgccgt agtatttacc cgcctgcgga tcgttgatga
    58021 caaccaccag cgcgaagcgc ggctgactcg caggcgcgac gcctgcggtg taagcaatgt
    58081 atttgttgat gtagcgaccg tccggcccca cttttttcgc cgtaccggtt ttaatcgcga
    58141 tacggtagcc tttaattgcc gccttcacgc cgccgccgcc cggcagcgcc acgctttcca
    58201 tcatatgcac cacggtgcgt acggtggatt cagggaagat gcgttcgccg ggtacaggcg
    58261 gatcaacttt ggtaatcgac agcgggcgat aaatgccata gctgccgatc gttgcataaa
    58321 ctcgcgctaa ctgtaacggc gttaccatta gcccgtagcc gaaagagaag gtggccctct
    58381 ctatgtcgga ccaccgttgt ttttgaggat ataagccact gcgttctccg accaacccca
    58441 aattggtcgc ctttcctagc ccaaaacgtg agtaagtatc tactaacgct gaggacggca
    58501 tcgctaacgc cagtttggat acaccgacgt tactcgactt ctgtagaacc ccagtcaggg
    58561 ttaattcgct gtagcgcgcc acgtctttaa tttcgtggcc gttaattcgg tatggaacgg
    58621 tattcaacac cgtattttcg ttgacgatac cgcgctgaag cgcagtcatc accaccatcg
    58681 gcttaaccgt agaacccggt tcaaacacgt cggtgatggt acggttacgc atcgcgtctt
    58741 tcggcgtacc ggcaaggttg ttggggttat aggaagggct attcgccatc gccagtactt
    58801 caccggtatt gacatcgacc agcaccgcgc taccggattc cgccttgtta aacgccaccg
    58861 cgttgttcag ttcgcggtaa accagcgcct gtaagcgttc atcaatgctt aacgccaggt
    58921 tgtgcgctgc ctgactgtca gtggaggaga tatcctcaat cacgcggcca tagcggtctt
    58981 tacgcacgat tcgctcgcca ggctgaccgg taagccactt atcaaagctc ttttcaacgc
    59041 cttcaatccc ctgactgtca acgttggtaa aaccgatgag gtgagcggtt acttctcctg
    59101 acgggtagta gcggcgtgat tcttcacgca aatgaatccc cggcagtttg agttttttga
    59161 tgtagtccgc catgtcagga tttacctggc gcgccagata aataaaacgc cctttcgggt
    59221 tggcgttgat acgggcggag agctgatcga gcggaatatt gagcgcagta gaaagcgctt
    59281 tccagcgatc gccgacgctg atgccgccgg cgtcatgaac ttctttcggg tcggcccaga
    59341 tcgccttaac cggtacgctg accgccagtg gacgcccgga acggtcggta atcataccgc
    59401 gtgaggtgga gacttcctga acacgcagcg aacgcatatc gccctgacgc accagcatat
    59461 ccggggcgat aatctgtagc cacgccgcgc gtccaagtaa aaaaaccagc gccagtaaaa
    59521 tacagccgca cagcaacgca aaacgccaac tgatgaagtt ggtctgttct tcctggcgct
    59581 tcgatttttg cgtttttgcc gctgctttca tgcgtcgcgt ttatccttat ttttgcacta
    59641 cgatattttc ttgggacgga tcaacatgct gcatttgcag cttttccgtt gcgatccgct
    59701 ctacccggct gtgatcgccg agcgcatttt cttcaaggat caggttgcgc cattcaatgt
    59761 ccaatgcatc gcgctccaga accagttgtt cacgctgagc ggtgagtaaa cgagtatggt
    59821 gcgccgtcgt gaccaccgtc accgccgtta aaatgatgca aatgaacaag cagagtggca
    59881 gcttcccgaa ccgcaaaaga tcgtcaccga tcacgccagg caaggcatgg cgctcgttgc
    59941 ttcctatcga tcccttaact ttgcttaggg cttctgtcac tctgctgatc atgcgttcgt
    60001 cctctctgcg atacgcagaa ctgaactacg ggcccgagga ttttcagcta cctctttttc
    60061 acccggcatc aacttgccta acgctcgtaa ctcacgaccg cccagttttt tgagctgcgc
    60121 ttccgtcatc ggtaatcccg ccggtacctg cggaccgcgg ctttgctcac gcataaagcg
    60181 tttcacaata cggtcttcca gcgagtggaa actgatgatt gaaagccgcc cgcctgaggc
    60241 cagtacgctg agcgagcttt ttagcgcctg ctctatctcc tccagttcac tgtttaccca
    60301 gatgcgcacc gcctggaagg tacgggtcgc gggatgtttg aatttgtctt ttaccggggt
    60361 cgccgccgca accacttccg ccagctcttt ggtgcgggtc atcggctgtt cgcgattgcg
    60421 ctcaacaatg gcgtgagcaa tacgtttggc aaaacgctcc tcgccgaatg ttttcagcac
    60481 ccaggcgata tccgcctcct ccgccgtttg taaccactcg gcggcagact ggccgcgcgt
    60541 cgggtccatt cgcatatcca gcggaccgtc gcgcataaat gaaaaaccgc gctccgcatc
    60601 gtcaagctgc ggagaagaga cgccaagatc gagaaggatc ccgtcaatct tgccggtaag
    60661 ctcgcgctcg gcgacataat cagccagcgc ggaaaaaggt ccatgaatga tggagaagcg
    60721 aggatcatta atggtctgcg caacggcgat cgcctgcgga tcgcgatcga tcgccagcaa
    60781 gcgcccctct tcgcccagtt gcgagaggat caggcgcgag tggccgccgc gaccaaatgt
    60841 gccatcaata tagataccat ccggacgaat attcagccca ttaacggctt catccaacag
    60901 taccgtagtg tgtttaaaat tttccatcat cttatagaga caagtcctgc agccgctccg
    60961 ataacgtttc ggtagctgac tgttcagcgt cgatatcttc cttgacctgt tgataccagg
    61021 tcgtttcatc ccacagctca aatttgttga actgtccaac cagcatcact tctttcgtca
    61081 gtccggcatg ttgccgcaga actggcgcga tcagtaatcg acctgcacca tccatctgac
    61141 attcactggc atggcccaac agtaaacgct gtacgcgacg ttctaccggg ttcatgctcg
    61201 acagacgaga taacttttgc tcaataattt cccattcagg cagggggtaa agcagcaggc
    61261 atgggtgatg gatgtcaatg gtacatacta tttgaccggt agcgctctcg atcagttgct
    61321 cccgataacg ggtcggcacg gtcaggcgcc ctttactgtc gagattgact aacgttgccc
    61381 cccggaacat gccagtctca ccccttctta ccactttatc ccacaaattc ccactcgaag
    61441 gagtttacgg agcggaggaa aagcttgtca agcaagtcac aacgcttacc gaagtaaaaa
    61501 agccaatgtt tacggcgaat atctgcgttg attaatttcc gcccagcgcg caagccaaat
    61561 taacgttatg aatatttgta agaaaaaaac caaagaccca ccgccgttta aaacggactc
    61621 aatataatcc gagaaaaata taaagtgtca gtttgcgacg cgagcggcat tttaggacat
    61681 attgcaccgt gttaacagtg cctgtttaac gtgtgcggcg cctgctatac cagcgcctac
    61741 aagcgactgt cgcgccaaag acaaaaagtg gctgttaatt cgacgatttc ttgcctgctt
    61801 gtaacaaaac aatacaa
//
LOCUS       DAJVBX010000004        61524 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.004, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000004 DAJVBX010000000
VERSION     DAJVBX010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 61524)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61524)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61524
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.004"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..493
                     /gene="sthA"
                     /locus_tag="OPV72_000177"
     CDS             <1..493
                     /gene="sthA"
                     /locus_tag="OPV72_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="fimbrial protein SthA"
                     /protein_id="HCR9912598.1"
                     /translation="PVFAQNTITFNGKIYDQACTVQVNGSTDTTIDLGNYSKERIAEK
                     GATTDYVPFTVSLVSCPEAGTGVPTQAMFRFHGATDDSNPTYFKNADEGSETGAAGVG
                     ISIQNASHSDVTDNTDDAAVSLPTDGSTADFTYYAAMANDGSATVTGGDVSTQVTYTV
                     SYQ"
     gene            564..1247
                     /locus_tag="OPV72_000178"
     CDS             564..1247
                     /locus_tag="OPV72_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial assembly chaperone"
                     /protein_id="HCR9912599.1"
                     /translation="MKHIKKSVLVVLLTSHVAHASIVVGGTRLVFDGNNDESSINVEN
                     KDSKANLVQSWLSVADPQVTNKQVFIITPPLFRLDAGQKNSIRVIRSGAPLPADRESM
                     YWLNIKGIPSIDDNASANRVEISINTQIKLIYRPPALTKSTPDSQSQQLKWQTAGDVI
                     TVNNPTPYYMNFASVTLNSHEVKSATFVPPKSSASFKLSSTAAPHGTVTWRLISDYGM
                     SLEPHSGSF"
     gene            1293..3829
                     /locus_tag="OPV72_000179"
                     /pseudo
     CDS             1293..3829
                     /locus_tag="OPV72_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463449.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial outer membrane usher protein"
     gene            3847..4404
                     /locus_tag="OPV72_000180"
     CDS             3847..4404
                     /locus_tag="OPV72_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein SthD"
                     /protein_id="HCR9912600.1"
                     /translation="MNMNRFAALAALLTFTGLASWSPSISAAYNTADAVDINVTGLIY
                     ADPCTVTVPDTISLGQYARADIAVAGGNTATIPFTIKMTNCPATTTKAAISFNGVPYP
                     DPNYASAIYANSAANPAQDLGLQLFNLDSKSLVNLANNVTYTVDINSNTHEANLPVAA
                     RMYTPYGKVTAGDFTSVVTITIAWQ"
     gene            4445..5529
                     /locus_tag="OPV72_000181"
                     /pseudo
     CDS             4445..5529
                     /locus_tag="OPV72_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463447.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
     gene            complement(5587..6936)
                     /gene="creD"
                     /locus_tag="OPV72_000182"
     CDS             complement(5587..6936)
                     /gene="creD"
                     /locus_tag="OPV72_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope integrity protein CreD"
                     /protein_id="HCR9912601.1"
                     /translation="MLKSPLLWKMITLGGAMILLLIPLMMVRHTIVERADYRSHVEAA
                     IRQSTSGPQKVVGPLVAVPVTELYTVLEEEKEVQYKRSYLYFWLPESLLVEGNQNVEA
                     RKIGIYQGQVWHTDMAIKAEFDVARLHELNRPNITLGKPFIVVGVGDARGISAVKAPQ
                     VNGEMLTVEPGTGLPESREGIHIPLPDSQWATRNLTLAMSLNLSGTGSFSLVPVGRSS
                     EMTLTSNWPHPNFVGDFLPGKREISGSGFQAQWQTSRFATNLGEQFADAQKVDWDNLP
                     AFSVAVSTPADQYQLTDRATKYAILLITLTFMAFFVFETLTGQRLHPMQYLLVGLSLV
                     MFYLLLLALSEHIGFTPAWIAASLVGALMNSVYLQAVLKGWRNSVLFTLALLALDGVM
                     WGLLRSEDSSLLLGTGVLLLALGGVMFLTRHLDWYSLSCQQRKSLPPVKDDELRLWK"
     gene            complement(6994..8418)
                     /gene="creC"
                     /locus_tag="OPV72_000183"
     CDS             complement(6994..8418)
                     /gene="creC"
                     /locus_tag="OPV72_000183"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CreC"
                     /protein_id="HCR9912602.1"
                     /translation="MRIGMRLLLGYFLIVAVAAVFVLSIFVQEIKPGVRRATEGTLID
                     TATLLAALARDDLLSGNPTDGQLAKAFAQLQHRPFRANISGIVKVRNEYHVYMTDAQG
                     KVLFDSENKAVGQDYSRWNDVWLTLRGQYGARSTAKDSADPNSTVMYVAAPIISDGRI
                     IGVLTVGKPNAAMAPVIKRSERRILWASAVLLGIALAIGAGMVWWINRSIARLTRYAD
                     SVTENRPLALPALGSSELRKLAQALESMRIKLEGKNDIEQYVYALTHELKSPLAAIRG
                     AAEILREGPPADVVTRFTENILAQNTRMQALVETLLRQARLENRQDIPLAPVAVDELF
                     TQLSEARSIQLAAKKITLTLRPSSLVVVADAELLAQALGNVLDNAIDFTPENGVITLS
                     AQPMGEKAILQVTDSGCGIPDFALPRIFDRFYSLPRENGRKSSGLGLAFVSEAARLLN
                     GEVTLCNRPEGGVLASLTLHRHFT"
     gene            complement(8418..9107)
                     /gene="creB"
                     /locus_tag="OPV72_000184"
     CDS             complement(8418..9107)
                     /gene="creB"
                     /locus_tag="OPV72_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CreB"
                     /protein_id="HCR9912603.1"
                     /translation="MQQPQVWLVEDEQGIADTLIYTLQLEGFTVELFARGLPALEKAR
                     QQRPDAVILDVGLPDISGFELCRQLLERHPALPILFLTARSDEVDRLLGLEIGADDYV
                     AKPFSPREVSARVRTLLRRVKKFAAPSPVVRTGHFDLNEPAAQIAWFGTPLSLTRYEF
                     LLLKTLLLSPERVYSCQQLMDIVWSDAQETFDRTVDTHIKTLRAKLRAINPDLSPINT
                     HRGMGYSLRSI"
     gene            complement(9120..9593)
                     /gene="creA"
                     /locus_tag="OPV72_000185"
     CDS             complement(9120..9593)
                     /gene="creA"
                     /locus_tag="OPV72_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein CreA"
                     /protein_id="HCR9912604.1"
                     /translation="MKYKSLVLFSILLLLGQSARAEQIGSVDTVFKMFGPDHKIVVEA
                     FDDPDVKNVTCYVSRAKTGGIKGGLGLAEDTSDAAISCQQVGPIELSDKIKNGKAQGE
                     VVFKKRTSLIFKSLQVVRFYDEKRNTLAYLAYSDKVVDGSPKNAISAVPVMPWRQ"
     gene            9805..10674
                     /gene="robA"
                     /locus_tag="OPV72_000186"
     CDS             9805..10674
                     /gene="robA"
                     /locus_tag="OPV72_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MDR efflux pump AcrAB transcriptional activator
                     RobA"
                     /protein_id="HCR9912605.1"
                     /translation="MDQAGIIRDLLIWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKD
                     VTGHAIGAYIRARRLSKSAVALRLTARPILDIALQYRFDSQQTFTRAFKKQFSQTPAL
                     YRRSPEWSAFGIRPPLRLGEFTVPEHQFVTLEDTPLLGVTQSYSCSLEQISDFRHEMR
                     VQFWHDFLGHSPTIPPVLYGLNETRPSMEKDDEQEVFYTTALPQEQADGYVQSAHPVL
                     LQGGEYVMFTYEGLGTGVQDFILTVYGTCMPMLNLTRRKGQDIERYYPSEDTKTGDRP
                     INLRCEFLIPIRR"
     gene            complement(10671..11318)
                     /gene="gpmB"
                     /locus_tag="OPV72_000187"
     CDS             complement(10671..11318)
                     /gene="gpmB"
                     /locus_tag="OPV72_000187"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase GpmB"
                     /protein_id="HCR9912606.1"
                     /translation="MLQVYLVRHGETQWNAERRIQGQSDSPLTAKGEQQAMQVGERAR
                     SLGITHIISSDLGRTKRTAEIIAQACGCDITFDFRLRELDMGVLEKRQIDSLTEEEEG
                     WRRQLVNGTQDGRIPGGESMQELSDRVHAALASCLELPQGSRPLLVSHGIALGCLVST
                     ILGLPAWAERRLRLRNCSISRIDYQESQWLASGWVVETAGDVSHLDTPALDELQR"
     gene            11366..11701
                     /locus_tag="OPV72_000188"
     CDS             11366..11701
                     /locus_tag="OPV72_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF84 family protein"
                     /protein_id="HCR9912607.1"
                     /translation="MHQVISATTNPAKIQAILQAFEEIFGEGSCHITPVAVESGVPEQ
                     PFGSEETRAGARNRVGNARRLHPQADFWIGRKEGAIGVFTAGKLTRSSVYYQAVILAL
                     SPFHNAVYR"
     gene            complement(11803..12129)
                     /gene="trpR"
                     /locus_tag="OPV72_000189"
     CDS             complement(11803..12129)
                     /gene="trpR"
                     /locus_tag="OPV72_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trp operon repressor"
                     /protein_id="HCR9912608.1"
                     /translation="MTQHSPYSSAIAEQRNQEWLRFVELLRQAYAEDLHLPLLQLMLT
                     PDEREALGTRVRIIEELLRGEMSQRELKTELGAGIATITRGSNSLKSAPVELRHWLEQ
                     ILLKSA"
     gene            complement(12187..14124)
                     /gene="sltY"
                     /locus_tag="OPV72_000190"
     CDS             complement(12187..14124)
                     /gene="sltY"
                     /locus_tag="OPV72_000190"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418809.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein transglycosylase"
                     /protein_id="HCR9912609.1"
                     /translation="MDRAKPFVWRLVAASVCLLTFCHLARADSLEEQRNRYAQIKQAW
                     DNRQMDVVEQMMPGLKDYPLYPYLEYRKITDDLMNQPAIAVTQFVRANPTLPPARTLQ
                     SRFVNELARREDWRGLLAFSPEKPGTTEAQCNYYYAKWSTGQTEAAWQGAKDLWLTGK
                     SQPNACDKLFSVWRASGKQDPLAYLERIRLAMKAGNTGLVTVLAGQMPAEYQTIASAI
                     ITLANDPNNVLTFARTTGATDFTRQMAEVAFASVARQDAENARLMIPSLVQAQKLNEE
                     QTQALRDIVAWRLMGNDVTDAQAKWRDDAIMRSQSTSLIERRVRMALGMGDRRGLNTW
                     LARLPMEAKEKDEWRYWQADLLLERGRDAEAKEILHALMQKRGFYPMVAAQRLGEEYT
                     LKIDKAPANVNSALTQGPEMARVRELMYWNLDNTARSEWANLVKSRSKSEQAQLARYA
                     FNQHWWDLSVQATIAGKLWDHLEERFPLAYNDLFTRYTRGKDISQSYAMAIARQESAW
                     NPKVKSPVGASGLMQIMPGTATHTVKMFSIPDYRGPGQLLEPETNINIGTSYLQYVYQ
                     QFGNNRIFASAAYNAGPGRVRTWLGNSAGRIDAVAFVESIPFSETRGYVKNVLAYDAY
                     YRHFMGQKEALMSDSEWQRRY"
     gene            14333..16000
                     /gene="ettA"
                     /locus_tag="OPV72_000191"
     CDS             14333..16000
                     /gene="ettA"
                     /locus_tag="OPV72_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017145039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-dependent translational throttle protein
                     EttA"
                     /protein_id="HCR9912610.1"
                     /translation="MAQFVYTMHRVGKVVPPKRHILKNISLSFFPGAKIGVLGLNGAG
                     KSTLLRIMAGLDKDIEGEARPQPGIKIGYLPQEPQLNPEHTVRESIEEAVSEVVNALK
                     RLDEVYALYADPDADFDKLAAEQGRLEEIIQAHDGHNLNVQLERAADALRLPDWDAKV
                     EKLSGGERRRVALCRLLLEKPDMLLLDEPTNHLDAESVAWLERFLHDFEGTVVAITHD
                     RYFLDNVAGWILELDRGEGIPWEGNYSSWLEQKDQRLAQEASAEAARRKSIEKELEWV
                     RQGAKGRQSKGKARLARFEELNSVEYQKRNETNELFIPPGPRLGDKVIEVSNLRKSYG
                     DRVLIDDLSFSVPKGAIVGIIGPNGVGKSTLFRMMSGQEQPDSGTITLGETVKLASVD
                     QFRDAMDNSKTVWEEVSGGLDIMKIGNTEMPSRAYVGRFNFKGVDQGKRVGELSGGER
                     GRLHLAKLLQVGGNVLLLDEPTNDLDIETLRALENALLEFPGCAMVISHDRWFLDRIA
                     THILDYQDEGKVEFFEGNFTEYEEYKKRTLGAEALEPKRIKYKRIAK"
     gene            complement(16118..17350)
                     /gene="nadR"
                     /locus_tag="OPV72_000192"
     CDS             complement(16118..17350)
                     /gene="nadR"
                     /locus_tag="OPV72_000192"
                     /EC_number="2.7.1.22"
                     /EC_number="2.7.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463436.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multifunctional transcriptional
                     regulator/nicotinamide-nucleotide
                     adenylyltransferase/ribosylnicotinamide kinase NadR"
                     /protein_id="HCR9912611.1"
                     /translation="MSSFDYLKTAIKQQGCTLQQVADASGMTKGYLSQLLNAKIKSPS
                     AQKLEALHRFLGLEFPRRQKNIGVVFGKFYPLHTGHIYLIQRACSQVDELHIIMGYDD
                     TRDRGLFEDSAMSQQPTVSDRLRWLLQTFKYQKNIRIHAFNEEGMEPYPHGWDVWSNG
                     IKAFMAEKGIQPSWIYTSEEADAPQYLEHLGIETVLVDPERTFMNISGAQIRENPFRY
                     WEYIPTEVKPFFVRTVAILGGESSGKSTLVNKLANIFNTTSAWEYGRDYVFSHLGGDE
                     MALQYSDYDKIALGHAQYIDFAVKYANKVAFIDTDFVTTQAFCKKYEGREHPFVQALI
                     DEYRFDLVILLENNTPWIADGLRSLGSSVDRKAFQNLLVEMLKENNIEFVHVKEADYD
                     GRFLRCVELVKEMMGEQG"
     gene            complement(17501..18883)
                     /gene="radA"
                     /locus_tag="OPV72_000193"
     CDS             complement(17501..18883)
                     /gene="radA"
                     /locus_tag="OPV72_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001399683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HCR9912612.1"
                     /translation="MAKAPKRAFVCNECGADYPRWQGQCSACQAWNTITEVRLAASPT
                     VARNERLSGYAGSAGVSKVQKLSDISLEELPRFSTGFKEFDRVLGGGVVPGSAILIGG
                     NPGAGKSTLLLQTLCKLAEQMKTLYVTGEESLQQVAMRAHRLGLPTANLNMLSETSIE
                     QICLIAEEEQPKLMVIDSIQVMHMADIQSSPGSVAQVRETAAYLTRFAKTRGVAIVMV
                     GHVTKDGSLAGPKVLEHCIDCSVLLDGDADSRFRTLRSHKNRFGAVNELGVFAMTEQG
                     LREVSNPSAIFLSRGDEVTSGSSVMVVWEGTRPLLVEIQALVDHSMMANPRRVAVGLE
                     QNRLAILLAVLHRHGGLQMSDQDVFVNVVGGVKVTETSADLALLLAMVSSLRDRPLPQ
                     DLVVFGEVGLAGEIRPVPSGQERISEAAKHGFRRAIVPAANVPKKPPEGMQVFGVKKL
                     ADALSVFDDL"
     gene            complement(18967..19935)
                     /gene="serB"
                     /locus_tag="OPV72_000194"
     CDS             complement(18967..19935)
                     /gene="serB"
                     /locus_tag="OPV72_000194"
                     /EC_number="3.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoserine phosphatase"
                     /protein_id="HCR9912613.1"
                     /translation="MPNITWCDLPEDVSLWPGLPLSLSGDEVMPLDYHAGRSGWLLYG
                     RGLDKQRLTQYQTKLGAAMVIVAAWCVEDYQVIRLAGSLTPRATRLAHEAQLDVAPLG
                     KIPHLRTPGLLVMDMDSTAIQIECIDEIAKLAGTGEKVAEVTERAMRGELDFTASLRS
                     RVATLKGADADILRQVRGNLPLMPGLTQLVLKLEALGWKIAIASGGFTFFADYLRDQL
                     RLTAAVANELEIMDGKFTGHVIGDIVDAEYKANTLLRLAQEHDIPLAQTVAIGDGAND
                     LPMIKAAGLGIAFHAKPKVNEKTEITIRHADLMGVFCILSGSMNQK"
     gene            20052..20696
                     /locus_tag="OPV72_000195"
     CDS             20052..20696
                     /locus_tag="OPV72_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463433.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtjB family periplasmic protein"
                     /protein_id="HCR9912614.1"
                     /translation="MARAKLKFRLHRAVIVLFCLTLLVALMQGASWFSQNHQRQRNPQ
                     LEELARTLARQVTLNIAPLMRSETPDENRINAVLRQLTQESHILDAGVYDEQGDLITR
                     AGESVNVRDRLALDGKKAGSYFNQQIVEPIQGKNGPLGYLRLTLDTHTLATEAKQVDN
                     TTNILRLMLLLSLAIGVVLTRTLLQGKRTRWQQSPFLLTASKPVPEEEEREEKE"
     gene            20730..21746
                     /gene="lplA"
                     /locus_tag="OPV72_000196"
     CDS             20730..21746
                     /gene="lplA"
                     /locus_tag="OPV72_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase LplA"
                     /protein_id="HCR9912615.1"
                     /translation="MTTLRLLISDSYDPWFNLAVEECIFRQMPATQRVLFLWRNADTV
                     VIGRAQNPWKECNTRRMEEDNVRLARRSSGGGAVFHDLGNTCFTFMAGKPEYDKTIST
                     HIVLAALNSLGVMADASGRNDLVVKTPDGDRKVSGSAYRETKDRGFHHGTLLLNADLS
                     RLANYLNPDKKKLAAKGITSVRSRVANLTELLPGITHEQVCQAVTEAFFAHYGERIDA
                     EVISPDKTPDLPNFTETFARQSSWEWNFGQAPAFSHLLDERFTWGGVELHFDVEKGVI
                     TRAQAFTDSLNPAPLEALAGRLQGCQYRADKLQETCEALIATFPEQESELRELANWVA
                     GAVR"
     gene            complement(21837..22322)
                     /locus_tag="OPV72_000197"
     CDS             complement(21837..22322)
                     /locus_tag="OPV72_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCR9912616.1"
                     /translation="MSNYRRYYINGGTWFFTVNLKNRKSDLLVRQIAELRSAIRRVKN
                     TKPFQIDAFVVLPEHLHCIWTLPENDCDFSSRWRELKKLFTKSIMRHDVWQPRFWEHT
                     IRDEKDFRRHVDYLYFNPVKHGWVRRVQDWPFSTFHRDVRNGVYPVDWAGEVRDLDAG
                     E"
     gene            complement(22529..23248)
                     /gene="deoD"
                     /locus_tag="OPV72_000198"
     CDS             complement(22529..23248)
                     /gene="deoD"
                     /locus_tag="OPV72_000198"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HCR9912617.1"
                     /translation="MATPHINAEMGDFADVVLMPGDPLRAKHIAETFLEDVREVNNVR
                     GMLGFTGTYKGRKISVMGHGMGIPSCSIYTKELITDFGVKKIIRVGSCGAVRMDVKLR
                     DVVIGMGACTDSKVNRIRFKDHDFAAIADFDMVRNAVDAAKALGVDARVGNLFSADLF
                     YSPDGEMFDVMEKYGVLGVEMEAAGIYGVAAEFGAKALTICTVSDHIRTHEQTTAAER
                     QTTFNDMIKIALESVLLGDKE"
     gene            complement(23458..24681)
                     /gene="deoB"
                     /locus_tag="OPV72_000199"
     CDS             complement(23458..24681)
                     /gene="deoB"
                     /locus_tag="OPV72_000199"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HCR9912618.1"
                     /translation="MKRAFIMVLDSFGIGATEDADRFGDVGSDTLGHIAEACAKGEAD
                     NGRKGPLNLPNLTRLGLVKAHEGSTGKIAAGMDGNADVIGAYAWAHELSSGKDTPSGH
                     WEIAGVPVLFDWGYFSDHENSFPQELLDKLVKRANLPGYLGNCHSSGTVILDQLGEEH
                     MKTGKPIFYTSADSVFQIACHEETFGLDKLYELCEIAREELTEGGYNIGRVIARPFIG
                     DKAGNFQRTGNRHDLAVEPPAPTVLQKLVDEKQGHVVSVGKIADIYANCGITKKVKAT
                     GLDALFDATLKEMKEAGDKTIVFTNFVDFDSSWGHRRDIAGYAAGLELFDRRLPELME
                     LVGEDDILILTADHGCDPSWTGTDHTREHIPVLIYGPKVKPGSLGHRETFADIGQTLA
                     TYFGTSPMDYGKNML"
     gene            complement(24733..26055)
                     /gene="deoA"
                     /locus_tag="OPV72_000200"
     CDS             complement(24733..26055)
                     /gene="deoA"
                     /locus_tag="OPV72_000200"
                     /EC_number="2.4.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine phosphorylase"
                     /protein_id="HCR9912619.1"
                     /translation="MFLAQEIIRKKRDGHALSDEEIRFFINGIRDNTISEGQIAALAM
                     TIFFHDMTMPERVSLTMAMRDSGTVLDWKSLNLNGPIVDKHSTGGVGDVTSLMLGPMV
                     AACGGYVPMISGRGLGHTGGTLDKLEAIPGFDIFPDDNRFREIIQDVGVAIIGQTSSL
                     APADKRFYATRDITATVDSIPLITGSILAKKLAEGLDALVMDVKVGSGAFMPTYELSE
                     ALAEAIVGVANGAGVRTTALLTDMNQVLASSAGNAVEVREAVQFLTGEYRNPRLFDVT
                     MALCVEMLISGQLAKDDAEARAKLQAVLDNGKAAEVFGRMVAAQKGPSDFVENYDKYL
                     PTAMLSKAVYADTEGFISAMDTRALGMAVVSMGGGRRQASDTIDYSVGFTDMARLGDS
                     IDGQRPLAVIHAKDEASWQEAAKAVKAAIILDDKAPASTPSVYRRITE"
     gene            complement(26178..26957)
                     /gene="deoC"
                     /locus_tag="OPV72_000201"
     CDS             complement(26178..26957)
                     /gene="deoC"
                     /locus_tag="OPV72_000201"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005097947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HCR9912620.1"
                     /translation="MTDLKASSLRALKLMDLTTLNDDDTNEKVIALCHQAKTPVGNTA
                     AICIYPRFIPIARKTLKEQGTPDIRIATVTNFPHGNDDIDIALAETRAAIAYGADEVD
                     VVFPYRALIAGNEQVGFDLVKACKDACAAANVLLKVIIETGELKEEALIRKASEISIK
                     AGADFIKTSTGKVPVNATPESARIMMEVIRDMGVSKTVGFKPAGGVRTAEDAQKFLAI
                     ADELFGANWADSRHYRFGASSLLASLLKALGHGDGKSASSY"
     gene            27217..28767
                     /locus_tag="OPV72_000202"
     CDS             27217..28767
                     /locus_tag="OPV72_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjI family glycine radical enzyme"
                     /protein_id="HCR9912621.1"
                     /translation="MPASCETALQQRCQQIVTSPVLTPEQKRHFLALEAENALPYPTL
                     PEDARQALDEGVICDMFEGHAPFKPRYVLPDYARFLANGSQWLELEGAKDLDDALSLL
                     TILYHHVPSVTSMPVYLGQLDALLQPYVRILTQDAIDIRIKRFWRYLDRTLPDAFMHA
                     NIGPADTPVTRAILRADAELKQVAPNLTFIYDAEITPDDLLLEVAKNICECSKPHISN
                     GPVNDKIFTKGHYGIVSCYNSLPLAGGGSTLVRLNLKAVAERSTSVDDFFSRTLPHYC
                     RQQIAIINSRCEFLYEKSHFFENSFLVQEGLIDPERFAPMFGMYGLAEAVNLLCENAG
                     LTARYGKNETANELGYRISAQLADFVENTPVKYGRKQRALLHAQSGISSDIGTTPGAR
                     LPYGDEPDPITHLQTVAPHHAFYHAGISDILTLDETIKRNPQALVQLCLGAFKAGMRE
                     FTANVSGNDLVRVTGYMVRLSDLAKFRAEGSRTNTTWLGEEAARNTRILERQPRVVSH
                     EQQMRFSQ"
     gene            28739..29602
                     /locus_tag="OPV72_000203"
     CDS             28739..29602
                     /locus_tag="OPV72_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjW family glycine radical enzyme activase"
                     /protein_id="HCR9912622.1"
                     /translation="MNNRCALVSKIIAFSCVDGPGSRLALFLQGCNLRCKNCHNPWTM
                     GRCNDCGECVSQCPHHALSIDGGKVVWRSDVCEQCDTCLKMCPQQATPMAQTMSIDDV
                     LRHIRKASLFIEGITVSGGEATTQLPFIVALFTALKADPQLQRLTCLVDSNGQLSETG
                     WQKLLPVCDGVMLDLKAWKSECHHRLTGRDNTHIKHSIRFLAARGKLAELRLLVIPGQ
                     VDYAAHIDSLAAFITSLGEVPVRLNAFHAHGVYGEAKAWPGATPQEVERLADGLRARG
                     VAKLILPALYL"
     gene            complement(29635..30408)
                     /locus_tag="OPV72_000204"
     CDS             complement(29635..30408)
                     /locus_tag="OPV72_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HCR9912623.1"
                     /translation="MSWRFIDTHCHFDFPPFTGDERASIQRACEAGVEKIIVPATEAA
                     HFPRVLALAARFPSLYAALGLHPIVIERHADDDPDKLQQALAQQQNVVAVGEIGLDLY
                     RDDPQFARQERFLDAQLQLAKRYDLPVILHSRRTHDKLAMRLKRQSLPQTGVVHGFSG
                     SLQQAERFVQLGYKIGVGGTITYPRASKTRDVMARLPLDALLLETDAPDMPLKGFQGQ
                     PNRPEQAARVFDALCELRPEPAEVIADTLYRNTVTLFRL"
     gene            complement(30405..31478)
                     /locus_tag="OPV72_000205"
     CDS             complement(30405..31478)
                     /locus_tag="OPV72_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin family protein"
                     /protein_id="HCR9912624.1"
                     /translation="MGQRIPVTLGNIAPLSLTPFRSGRMALVCEGGGQRGIFTAGVLD
                     EFMRAQFNPFHLYFGTSAGAQNLSAYLCNQPGYGRKVIMRYTTRREFFDPLRFVRGGN
                     LIDLDWLVESTAARMPLQMDTSARLFDSGKSFYMCACRGDDYTPGYFSPTKQNWLDII
                     RASSAIPGFYRTGVTLEGINYLDGGISDAIPVQEAAKRGAKTIVVIRTVPSQMYYTPQ
                     WFKRMERWLGESSLQPLVNLVQHHETSYSAIQQFIEKPPGKLRIIEIYPPKPLHSMAL
                     GSRIPALREDYKTGQLCGRYFLATVGKLLAATPPLLRHSSRIAVPETVVVPPAPVAND
                     THVAEVISAPQANDTTFTDEDLA"
     gene            complement(31602..31763)
                     /locus_tag="OPV72_000206"
     CDS             complement(31602..31763)
                     /locus_tag="OPV72_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1328 domain-containing protein"
                     /protein_id="HCR9912625.1"
                     /translation="MFRWGIIFLVIALIAAALGFGGLAGTAAGAAKIVFVVGIVLFLV
                     SLFMGRKRP"
     gene            complement(31892..32509)
                     /gene="osmY"
                     /locus_tag="OPV72_000207"
     CDS             complement(31892..32509)
                     /gene="osmY"
                     /locus_tag="OPV72_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone OsmY"
                     /protein_id="HCR9912626.1"
                     /translation="MTMTRLKISKTLLAVMLTSAVATGSAFAENATTDKAQSGTETAG
                     QKVDSSMNKVGNFMDDSAITAKVKAALVDHDNIKSTDISVETNQKVVTLSGFVESQAQ
                     AEAAVKVAKGVEGVTSVSDKLHVRDNKEGSVKGYAGDTATTSEVKAKLLADDLVPSRK
                     VKVETTDGVVQLSGTVETQEQSDRAESIAKAVDGVKSVKNDLKVQ"
     gene            complement(32911..34500)
                     /gene="prfC"
                     /locus_tag="OPV72_000208"
     CDS             complement(32911..34500)
                     /gene="prfC"
                     /locus_tag="OPV72_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HCR9912627.1"
                     /translation="MTLSPYLQEVAKRRTFAIISHPDAGKTTITEKVLLFGQAIQTAG
                     TVKGRGSSQHAKSDWMEMEKQRGISITTSVMQFPYHDCLVNLLDTPGHEDFSEDTYRT
                     LTAVDCCLMVIDAAKGVEDRTRKLMEVTRLRDTPILTFMNKLDRDIRDPMELLDEVEN
                     ELKIGCAPITWPIGCGKLFKGVYHLYKDETYLYQTGKGHTIQEVRIVKGLNNPDLDAA
                     VGEDLAQQLRDELELVQGASNEFDEELFLAGEITPVFFGTALGNFGVDHMLDGLVAWA
                     PAPMPRQTDTRTVEASEERFTGFVFKIQANMDPKHRDRVAFMRVVSGKYEKGMKLRQV
                     RTGKDVVISDALTFMAGDRSHVEEAYPGDILGLHNHGTIQIGDTFTQGEMMKFTGIPN
                     FAPELFRRIRLKDPLKQKQLLKGLVQLSEEGAVQVFRPISNNDLIVGAVGVLQFDVVV
                     ARLKSEYNVEAIYESVNVATARWVESADAKKFEEFKRKNETQLALDGGDNLTYIAPTM
                     VNLNLTQERYPDVQFRKTREH"
     gene            complement(34592..35269)
                     /gene="yjjG"
                     /locus_tag="OPV72_000209"
     CDS             complement(34592..35269)
                     /gene="yjjG"
                     /locus_tag="OPV72_000209"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine 5'-nucleotidase"
                     /protein_id="HCR9912628.1"
                     /translation="MKWDWIFFDADETLFTFDSFTGLQRMFLDYSVTFTAEDFQDYQA
                     VNKPLWVDYQNGAITSLQLQHARFQSWAERLNVAPGRLNDAFISAMAEICSPLPGAVS
                     LLNAIRGQAKIGIITNGFTALQQTRLERTGLREYFDLLVISEQVGVAKPDPKIFNYAL
                     EQAGNPDRSRVLMVSDTAESDILGGINAGLSTCWLNAHHREQPAGIHPTWTVASLSEL
                     EQLLCKH"
     gene            complement(35291..35737)
                     /gene="rimI"
                     /locus_tag="OPV72_000210"
     CDS             complement(35291..35737)
                     /gene="rimI"
                     /locus_tag="OPV72_000210"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HCR9912629.1"
                     /translation="MNTISILSTTDLPAAWQIEQRAHAFPWSEKTFFGNQGERYLNFK
                     LTADDRMAAFAITQVVLDEATLFNIAVDPDFQRRGLGRMLLEHLIDELEKRGVVTLWL
                     EVRASNAAAIALYESLGFNEATIRRNYYPTAQGHEDAIIMALPISM"
     gene            complement(35682..36119)
                     /locus_tag="OPV72_000211"
     CDS             complement(35682..36119)
                     /locus_tag="OPV72_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit psi"
                     /protein_id="HCR9912630.1"
                     /translation="MTSRRDWQLQQLGITQWALRRPGALQGEIAISLPAHVRLIVVAE
                     ELPALNEPLMRDILRALTVSPDQVLPLTPERVAMLPQGSRCNSWRLGTDAPLQLEGAQ
                     VTTPAFNELRVNPAARAALWQQICEHEHDFYPQHDRSPRSLAD"
     gene            36222..37250
                     /gene="rsmC"
                     /locus_tag="OPV72_000212"
     CDS             36222..37250
                     /gene="rsmC"
                     /locus_tag="OPV72_000212"
                     /EC_number="2.1.1.172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(1207)-N(2))-methyltransferase
                     RsmC"
                     /protein_id="HCR9912631.1"
                     /translation="MSAFTPASEVLLRHSDDFEQSRILFAGDLQDDLPARFECAASRA
                     YTQQFHHWQALSRQMGDNVRFSLVAQASDVADCDTLIYYWPKNKPEAQFQLMNILSLM
                     PVGSDVFVVGENRSGVRSAEPMLADYAPLNKVDSARRCGLYHGRLEKQPQFSLESWWA
                     EYNIDGLTIKTLPGVFSRDGLDVGSQLLLSTLTPHTKGKVLDVGCGAGVLSAALASHS
                     PKVRLTLCDVSAPAVEASRATLAANGLEGEVFASNVFSEVKGRFDMIISNPPFHDGMQ
                     TSLDAAQTLIRGAVRHLNSGGELRIVANAFLPYPKILDETFGFHEVIAQTGRFKVYRI
                     VMTRQAKK"
     gene            37441..37527
                     /locus_tag="OPV72_000213"
     tRNA            37441..37527
                     /locus_tag="OPV72_000213"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:37475..37477,aa:Leu,seq:cag)
     gene            37555..37641
                     /locus_tag="OPV72_000214"
     tRNA            37555..37641
                     /locus_tag="OPV72_000214"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:37589..37591,aa:Leu,seq:cag)
     gene            37673..37759
                     /locus_tag="OPV72_000215"
     tRNA            37673..37759
                     /locus_tag="OPV72_000215"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:37707..37709,aa:Leu,seq:cag)
     gene            complement(37791..38027)
                     /locus_tag="OPV72_000216"
     CDS             complement(37791..38027)
                     /locus_tag="OPV72_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1435 domain-containing protein"
                     /protein_id="HCR9912632.1"
                     /translation="MLQRTLGSGWGVLLPGVIIVGLAFIGLSAYALKLLIVSGLLLSA
                     LMLYHKQLRHFVLLPSCIALIGGMMLAMMNWNQG"
     gene            38278..39342
                     /locus_tag="OPV72_000217"
     CDS             38278..39342
                     /locus_tag="OPV72_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HCR9912633.1"
                     /translation="MTTPSWRSLRIKKYQFSLRLFLFLSAVSALFTLVFPLYQINVFC
                     TPMIGIVGLSVLLLIWHGKYGQKRINLPFISLLFGGIWAARIALKYPALGHYDFSFLL
                     ISLLSVLFIGSIAFAANIVAFTLYSLPPVAVCLWLNGNEQGLRILYLLALPMVGIAIQ
                     HVIQKRYDNFAQQLMFKLLAERETLNGLSMLDPLTGLYNRRGLQNRLDTLQAPGSHEH
                     YVLLLDIDHFKAYNDHYGHMMGDQALIRVSAAIRDAVRSRDVVCRFGGEEFLVLLTTA
                     EPQQARATAERIRQEVYDLKIPHMFNESVATNVTVSIGIAPLTDRNIGDAIEKADKAL
                     YEAKHLGRNHILVSDDMRAL"
     gene            39463..40251
                     /gene="fhuF"
                     /locus_tag="OPV72_000218"
     CDS             39463..40251
                     /gene="fhuF"
                     /locus_tag="OPV72_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore-iron reductase FhuF"
                     /protein_id="HCR9912634.1"
                     /translation="MAYRSAPIADDIIWRAAPQPEDASLADAVRETIASTRQHLLDFI
                     RLDETPPPTAMTLAQWTRPATFRSLLAAYSDHIYRHTPGLPRENKPLLSLWAQWYIGL
                     MTPPLMLALLTQARAINVSAEHIHVEFHETGRAACFWLDVHQDNLATERSPEERMETL
                     IVSALQPVIQALEATGDINAKLIWSNTGYLINWYLTEMKPLLGEALLATLRQRCFFEK
                     QLSDGQDNPLWRTVVMRDGLLVRRTCCQRYRLPDVQQCGDCTLK"
     gene            40402..40860
                     /locus_tag="OPV72_000219"
     CDS             40402..40860
                     /locus_tag="OPV72_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HCR9912635.1"
                     /translation="MSLQSVRQFLAAHAPDIEIIELNQSTATVELAAKAHNVEPGQIA
                     KTLSLKVKDTIILVVAKGDARLDNKKLKTTFGAKARMLSSDEVVNATGHPVGGVCPFG
                     LEHPLPVYCDISLKGYNEVLPAAGATHSAVRITPERMAELTSATWVDVCQ"
     gene            complement(40911..41585)
                     /gene="bglJ"
                     /locus_tag="OPV72_000220"
     CDS             complement(40911..41585)
                     /gene="bglJ"
                     /locus_tag="OPV72_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463407.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator BglJ"
                     /protein_id="HCR9912636.1"
                     /translation="MENRISKRNVALVEKCVMSTIGIKGLFDAMPDCRHTLHIFSKPS
                     AFYKAALKTPFSAVIFSLSALRTERRTGLSSLTELAINYPHMRRLVIADDDAEARLIS
                     ALSPLPLDGVISKASPLDVLQDALFTSLNSARRTTERTDNLWELHQNCMLSPTEREIL
                     RFMSNGYSMPQIAVQLERNIKTIRAHKFNVMSKLGVSSDAGLLDAADILLYLRAGDAT
                     ALQHRV"
     gene            complement(41546..42271)
                     /locus_tag="OPV72_000221"
     CDS             complement(41546..42271)
                     /locus_tag="OPV72_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCR9912637.1"
                     /translation="MLPGCCKNGLIISKTPLIQEGLKGAITGNFPDYKLAYCRTIEEL
                     TLLQLRRSNLVIADLAVNNASPRAICEYFYSLISQYRDIHWVFLVPKSCYPHAVDLLM
                     GPVSTLLSDEEPIENLISVIHAGNARSERISKTLLSPQVPSEIQQSHDRPIVLTLSER
                     KVLRLLGKGWGINQIAALLKKSNKTISAQKNSAMRRLSIHSNAEMYAWINSSQGAREL
                     NLPSVYGETMEWKTESAREMLRS"
     gene            42984..43760
                     /locus_tag="OPV72_000222"
     CDS             42984..43760
                     /locus_tag="OPV72_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418784.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter ThrE family protein"
                     /protein_id="HCR9912638.1"
                     /translation="MQEEQSIQRAVTRLCIQCGLLLLQHGAESALVDELSTRLGLALG
                     IDSVESAISSNAIVLTTIKDGQCLTSTRKNQDRGINMHVVTEVQHIVILAEHRLLDYK
                     GVEKRFSQLRPLRYPRWLVAFMVGLSCSCFCKLNNGGWDGAVITFFASMIAMYIRQML
                     AQRHLHPQINFCITAFVATTISGLMLTLPAFSQTPTIAMAASVLLLVPGFPLINSVAD
                     MFKGHINTGLARWAIASLLTLATCVGVVMSMTIWGLRGWV"
     gene            43751..44224
                     /locus_tag="OPV72_000223"
     CDS             43751..44224
                     /locus_tag="OPV72_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter"
                     /protein_id="HCR9912639.1"
                     /translation="MGIIDFLLALMQDMILSAIPAVGFAMVFNVPHRALPWCALLGAL
                     GHGLRMLMMSAGFNIEWSTFMASLLVGSIGIQWSRWYLAHPKVFTVAAVIPMFPGISA
                     YTAMISAVKISHLGYSEPMMITLLTNFLKASSIVGALSIGLSVPGLWLYRKRPRV"
     gene            44317..44856
                     /gene="dnaT"
                     /locus_tag="OPV72_000224"
     CDS             44317..44856
                     /gene="dnaT"
                     /locus_tag="OPV72_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaT"
                     /protein_id="HCR9912640.1"
                     /translation="MSSRILTSDVIGIDVLLHDHHAVLAKSTGGAVAVFANNAPAFYA
                     VTPARMAELLALEEKLSRPGSDVALDAQFYEEPEAAPVAIPCGKFAMYPAWQPDADFQ
                     RQAALWGVALREPVTAEELAAFIAYWQAEGKVFHHIQWQQKLARSVQISRSSNGGMPQ
                     RDINSVSEPDNHIPPGFRG"
     gene            44859..45596
                     /gene="dnaC"
                     /locus_tag="OPV72_000225"
     CDS             44859..45596
                     /gene="dnaC"
                     /locus_tag="OPV72_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein DnaC"
                     /protein_id="HCR9912641.1"
                     /translation="MKNVGDLMQRLQKMMPAHITPAFKTGEELLAWQKEQGEIRAAAL
                     ARENRAMKMQRTFNRSGIRPLHQNCSFDNYRVECDGQMNALSKARQYVDEFDGNIASF
                     VFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKDTFSNRETSEEQLLNDL
                     SNVDLLVIDEIGVQTESRYEKVIINQIVDRRSSSKRPTGMLTNSNMEEMTKMLGERVM
                     DRMRLGNSLWVNFSWDSYRSRVTGKEY"
     gene            45654..46115
                     /locus_tag="OPV72_000226"
     CDS             45654..46115
                     /locus_tag="OPV72_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2501 domain-containing protein"
                     /protein_id="HCR9912642.1"
                     /translation="MNTAKHVLCCAAIASVLISTSGIAASQLSAQGANAQQGGMSLSA
                     LTGLLSRGAQSLSADNMNNAAGILQYCAKQKLASATNVENVKNQILNKLGLDTTQQEQ
                     DTNYLNGLQGLLKTKDGQQLNLNNIGSTPLAEKVKTKACDLVLQQGLNFLS"
     gene            46398..48689
                     /gene="opgB"
                     /locus_tag="OPV72_000227"
     CDS             46398..48689
                     /gene="opgB"
                     /locus_tag="OPV72_000227"
                     /EC_number="2.7.8.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerol--membrane-oligosaccharide
                     glycerophosphotransferase"
                     /protein_id="HCR9912643.1"
                     /translation="MSELLSVALFLASVLIYAWKAGRNTWWFAATLTVLGLFVILNIT
                     LYASDYFTGDGINDAVLYTLTNSLTGAGVGKYILPGIGIALALVAVFGALGWVLRRRR
                     HHPHHVGYSLLALLLALGSVDASPAFRQITELVKSQMRDGDPDFAVYYKEPAKTIPHP
                     KLNLVYIYGESLERTYFDNDAFPNLTPELGALKNEGLDFSHTMQLPGTDYTIAGMVAS
                     QCGIPLFAPFEGNASASVSSFFPQNICLGDILKNSGYQNYFVQGANLRFAGKDVFLKS
                     HGFDHLYGAEELKTVVADPSYRNDWGFYDDTVLDEAWKKFEALSRSGQRFSLFTLTVD
                     THHPDGFISRTCNRKRYDYDGKPNQSFSTVSCSQENIAEFINKIKASPWFKDTVIVVS
                     SDHLAMNNTAWKYLNKQDRNNLFFILRGDKPQQETLAVKRNTMDNGATVLDILGGDNF
                     IGLGRSSLSGQSLSEVFLNVKEKVLAMKPDIIRLWNFPKEIKDFTVDRDKNMIAFSGS
                     HFRLPLLLRVSDKRVEPLPESEYSAPLRFQLADFAPRDNFVWIDRCYKMAQLWAPALA
                     LSTDWCVSQGQLGGQQTVQHVDKAQWQGKTAFKDTMIDMERYKGNVDTLKIVDNDIRY
                     KADSFIFNVAGAPEEVKQFSGISRPESWGRWSNAQLGDEVKIEYKAPLPKKFDLVITA
                     KAFGDNANRPIPVRVGNEEQTLVLGHDVSTITLHFNNPTDANTLVIAPPAPVSTNEGN
                     ILGHSPRKLGIGMVEIKVVNVES"
     gene            complement(48858..50518)
                     /gene="tsr"
                     /locus_tag="OPV72_000228"
                     /pseudo
     CDS             complement(48858..50518)
                     /gene="tsr"
                     /locus_tag="OPV72_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463392.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein"
     gene            50885..53035
                     /gene="btsT"
                     /locus_tag="OPV72_000229"
     CDS             50885..53035
                     /gene="btsT"
                     /locus_tag="OPV72_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate/proton symporter BtsT"
                     /protein_id="HCR9912644.1"
                     /translation="MDTKKIFKHIPWVILGIIGAFCLSVVALRRGEHVSALWIVVASV
                     SVYLVAYRYYSLYIAQKVMKLDPTRATPAVINNDGLNYVPTNRYVLFGHHFAAIAGAG
                     PLVGPVLAAQMGYLPGTLWLLAGVVLAGAVQDFMVLFISSRRNGASLGEMIKEEMGTV
                     PGTIALFGCFLIMIIILAVLALIVVKALAESPWGVFTVCSTVPIALFMGIYMRFLRPG
                     RVGEVSVIGIVLLVASIYFGGVIAHDPYWGPALTFKDTTITFALIGYAFVSALLPVWL
                     ILAPRDYLATFLKIGVIVGLALGIVILNPELKMPALTQYVDGTGPLWKGALFPFLFIT
                     IACGAVSGFHALISSGTTPKLLACETDARFIGYGAMLMESFVAVMALVAASIIEPGLY
                     FAMNTPPAGLGITMPNLHEMGGENAPLIMAQLKDVTAHAAATVSSWGFVISPEQILQT
                     AKDIGEPSVLNRAGGAPTLAVGIAHVFHKVLPMADMGFWYHFGILFEALFILTALDAG
                     TRSGRFMLQDLLGNFVPFLKKTDSLVAGIIGTAGCVGLWGYLLYQGVVDPLGGVKSLW
                     PLFGISNQMLAAVALVLSTVVLIKMQRTKYIWVTVIPAVWLLICTTWALGLKLFSANP
                     QMEGFFYMANLYKEKIANGTNLTAQQIANMNHIVVNNYTNAGLSILFLVVVYSIIFYG
                     FTTWMKVRNSDKRTDKETPYVPVPEGGVKISSHH"
     gene            53130..53333
                     /locus_tag="OPV72_000230"
     CDS             53130..53333
                     /locus_tag="OPV72_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbdD/YjiX family protein"
                     /protein_id="HCR9912645.1"
                     /translation="MFDTLGQAKKYLGQAAKMLIGIPDYDNYVEHMKTNHPDKPYMTY
                     EEFFRERQQARYGGDGKGGMRCC"
     gene            53344..54300
                     /gene="yjiA"
                     /locus_tag="OPV72_000231"
     CDS             53344..54300
                     /gene="yjiA"
                     /locus_tag="OPV72_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase"
                     /protein_id="HCR9912646.1"
                     /translation="MTPIAVTLLTGFLGAGKTTLLRHILNEQHGFKIAVIENEFGEVS
                     VDDQLIGDRATQIKTLTNGCICCTRSNELEDALLDLLDSRDRGDIAFDRLVIECTGMA
                     DPGPIIQTFFYHDVLCERYLLDGVIALVDAVHANEQMNQFTIAQSQIGYADRILLTKT
                     DVAGDSEKLRERLARINARAPVYTVVHGDIDLSQLFNTSGFMLEENVLASQPRFHFIA
                     DKQNDVSSIVVELDYPVDISEVSRVMENLLLESADKLLRYKGMLWIDGEPNRLLFQGV
                     QRLYSADWDRPWGDETPHSTLVFIGIQLPEDEIRAAFAGLRK"
     gene            complement(54375..54677)
                     /locus_tag="OPV72_000232"
     CDS             complement(54375..54677)
                     /locus_tag="OPV72_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BrnA antitoxin family protein"
                     /protein_id="HCR9912647.1"
                     /translation="MSMVKHKRGNASALSAQHEAELKALAKKSDDEIDYSDIPASEDG
                     QWSEAVRGKFFRPLKTQASVRIDADVMEWLKRPGKGYQTRLNAILREAMLREQNKK"
     gene            complement(54664..54951)
                     /locus_tag="OPV72_000233"
     CDS             complement(54664..54951)
                     /locus_tag="OPV72_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BrnT family toxin"
                     /protein_id="HCR9912648.1"
                     /translation="MPMEFEWDANKAKSNLRKHGVRFEDAVLVFDDPRHLSRQERYEN
                     GEYRWQTLGLVHGIVVILVAHSVRFESGFEVIRIISARKADRKERNRYEHG"
     gene            complement(55204..56118)
                     /locus_tag="OPV72_000234"
     CDS             complement(55204..56118)
                     /locus_tag="OPV72_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HCR9912649.1"
                     /translation="MAVPTYDKFIEPVLRFLATRPEGALVREVREAAAEMLGLNEQQR
                     AEVITSGQLTYQNRTGWAHDRLKRAGLSQSLSRGKWCLTPAGMSWVASHPQPMTEQEV
                     SHFACDFNGVKLSKPADAVALDPQPESIEDDELARSSPDDRLEQALNEIRESVAEELL
                     ENLLQVSPARFEVIVLDVLHRLGYGGHRGDLQRVGGTGDGGIDGIISLDKLGLEKVYV
                     QAKRWKGTVGSAEVRGFYGALPEQKVKRGVFITTSGFTAHARDYANKVEGLVLVDGDR
                     LVHLMIDNDIGVSSRLLKLPKLDMDYFE"
     gene            56316..59825
                     /gene="hsdR"
                     /locus_tag="OPV72_000235"
     CDS             56316..59825
                     /gene="hsdR"
                     /locus_tag="OPV72_000235"
                     /EC_number="3.1.21.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system
                     endonuclease"
                     /protein_id="HCR9912650.1"
                     /translation="MNKSNFDFLKGVNDFIYAIACAAENNYPDDPNTTLIKMRMFGEA
                     TAKHLGQLLDIPVCENQHDLLRELGKIAFIDDSILSVFHKLRRIGNLAVHEFHNDLDD
                     AQMCLRLGFRLSVWYYRLVTKDYDFPVPMFVLPEHGENLYHQEVLTLKQQLERQAQEK
                     VQSQAELEAQQQRLVALNGYIAILEGKQQETEAQTKARLAALEAQLAAKDAELAKQTE
                     QERKAYHKEITDQAIKRTLNLSEEESRFLIDAQLRKAGWQADSKTLRFAKGARPEPGV
                     NKAIAEWPTGTDETGKTGFADYVLFVGLKPIAVVEAKRKNTDVFSKLNESYRYSKYFD
                     NGFLRDTLLEHYAPDEVHDAVPEYEISWQDTSGKQRFKIPFCYSTNGREYRAAMKTKS
                     GIWYRDVRHTTNMSKALPEWHRPEELLDMLGSDPQKQNQWFAENPGMSELGLRYYQED
                     AVRAVEKAIVNGQQEILLAMATGTGKTRTAIALMFRLIQSQRFKRVLFLVDRRSLGEQ
                     ALGSFEDTRINGDTFNSIFDIKGLTDKFPEDSTKIHVATVQSLVKRTLQSDEPMPVGR
                     YDCIVVDEAHRGYILDKEQTEGELQFRSQLDYVSAYRRILDHFDAVKIALTATPALHT
                     VEIFGEPVYRYTYRTAVIDGYLIDQDPPIQIVTRNAQDGVYLSEGEQVERLNPQGELI
                     NDTLADDQDFEVADFNRGLVIPAFNRAVCGELTKYLDPIGQQKTLVFCVTNAHADMVV
                     DELRTAFKKKYPQLEHDAIIKITGDADKDAKKVQSMIVRFNKERLPNIVVTVDLLTTG
                     VDIPSICNIVFLRKVKSRILYEQMKGRATRLCPSVGKTSFKIYDCVDIYSSLESVDTM
                     RPVVVRPQVELQTLVNEITDSETYKTIEADGRSFAEHSHEQLVAKLQRIIGLATYNRD
                     HSETVDKQVRRLDELCLDAAGVNFGGLASRLREKGPHWSAEIFNKLPGFIARLERLKT
                     DINALRDAPIFLDIDDEVVSVKSLYGDYDTPQDFLEAFDALVQHAPNAQPALQAVINR
                     PRDLTRKGLVELQEWFDRQHFEESSLRSAWKETRNEDIAARLIGHIRRAAVGDALKPF
                     DERVDHALARIKGENDWSPEQLSWLDRLAQALKEKVVLDDDVFKTGNFHRRGGKSMLQ
                     RTFDDNLDSVLDKFSDYIWDELA"
     gene            59983..61380
                     /locus_tag="OPV72_000236"
     CDS             59983..61380
                     /locus_tag="OPV72_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HCR9912651.1"
                     /translation="MNNNDLVAKLWKLCDNLRDGGVSYQNYANELASLLFLKMCKETG
                     QEADYLPEGYRWDDLKSRIDQEQLQFYRKMLVHLGEDKKKLVQAVFHNVCTTITEPKQ
                     ITELVSNMDSLDWYSGTRGKSRDDFGDMYEGLLQKNANETKSGAGQYFTPRPLIKTII
                     HLLKPQPREVVQDPAAGTAGFLIEADRYVKSQTNDLDDLDGDTQDFQIHRAFIGLELV
                     PGTRRLALMNCLLHDIEGNLDHGGAIRLGNTLGSDGENLPQADIVATNPPFGSAAGTN
                     ITRTFVHPTSNKQLCFMQHIIETLRPGGRAAVVVPDNVLFDRVGLEIRRDLMDKCHLH
                     TILRLPTGIFYAQGVKTNVLFFTKGTVANPTQDKDCTDDVWVYDLRTNMPRFGKRTPF
                     TEQYLQPFETVYGEDPHGLSPRAEGEWSFNAEETEVADSEENKNTDQHQATSRWRKFS
                     REWIRTAKSDSLDIS"
BASE COUNT        14487 a        17038 c        15875 g        14124 t
ORIGIN      
        1 accggtattt gcccagaaca cgattacgtt caatggcaaa atttacgatc aggcgtgtac
       61 ggttcaggtt aatggctcca cggataccac cattgattta ggtaattaca gcaaagaacg
      121 catcgcggaa aaaggcgcca caaccgatta cgtgccgttt accgtaagcc tggttagctg
      181 cccggaagca gggactggcg taccgaccca ggccatgttc cgcttccacg gcgcaacaga
      241 tgattccaac ccaacgtact tcaaaaacgc ggacgaagga tcggaaacgg gcgccgcggg
      301 tgtcggtatt tctattcaga acgcttcaca tagcgatgtg acagataaca cggatgatgc
      361 cgcagtaagc ctgccaaccg acggctcgac agcagacttt acctattacg ccgccatggc
      421 aaacgatggt tccgcaaccg taaccggtgg agatgttagc actcaggtta cgtataccgt
      481 ttcgtatcag taaggcattc tcatcctgat gtggacaggc aggatgccag tccatagcgt
      541 aaaacatctt tacagagtaa aaaatgaaac acataaagaa atccgtgttg gtcgtattac
      601 tgacaagcca tgttgcccat gccagcattg ttgttggcgg aacccgactg gttttcgacg
      661 gcaataatga tgagtcgtca atcaatgtag agaataaaga cagcaaagcg aatcttgttc
      721 agtcatggtt atcggttgcc gatccccagg tcacaaataa gcaggtgttt attatcaccc
      781 cgcctctttt tcgccttgat gccgggcaaa agaacagtat tcgggttatt cgctctggcg
      841 cccctctacc tgcagatcgg gagtctatgt actggctcaa tattaagggt attccttcta
      901 ttgatgataa tgcctccgcg aaccgcgtgg aaatctccat taatacccaa ataaagctta
      961 tttatcgacc gccagcatta accaaatcaa cgcctgatag ccagagccaa caattaaaat
     1021 ggcagacggc aggggatgtt attaccgtaa ataaccctac cccctattat atgaactttg
     1081 ccagtgtgac gcttaacagc catgaagtga aatcagcgac cttcgttccg ccaaaatcat
     1141 cagcgtcatt taaattgagt tcgactgccg cccctcatgg tacggtaacg tggcgattaa
     1201 tcagcgatta tgggatgagt ttagagccgc attccggttc attctagcca ttaacgactt
     1261 cactttactt ttaccctttc aggactttta ctgtgcaatt ctccagagta gagccccgtt
     1321 ctcaattagc gttatcgttt ctctttatat gctgatccat aaaaccagcg ttagcgcatg
     1381 atcattttaa tccattatcg ttggaaaatg atgaaccggg cgtggagaat gtcgatctat
     1441 cggttttcga aaaggggggc aggcagaagg cacctataat gttgatattt atattaataa
     1501 cactaatgtt gaaacaaaaa atattgcctt taaaaataaa aaatcagcag ataataagct
     1561 ctccctacag ccatgtctta gcgttgaaca actcaagcag tggggcgtaa aaacagaaaa
     1621 cttccccgag cttaaaaatg acccaaacgg gtgtaccgat cttagtctgc tggctggcgc
     1681 tgtagcaaag tttaatgtca tcggtaaccg gctggattta gcgatccctc aaatcgcgtt
     1741 gatcgccgac ccgcgagaat tcgtccctac cagcaaatgg gatgaaggca ttaatgcttt
     1801 tttgctgaac tacagtttta ccggatcgca ggatcacgat attgatgaaa accggacgga
     1861 aaatagcgaa tacgctaacc tgcgccctgg tattaacatt ggcgcatggc gttttcgtaa
     1921 ctactcaacc tggaatcatg atagcgatgg gcaaaatagc tgggattctg cctacaccta
     1981 tgtttctcgc gatatcgaat ttttaaaagg acagctgatc gccggggaaa ataacacgcc
     2041 cgcagacgtc tttgacagta tttcatttaa gggcgtacag atctcttctg atgacgatat
     2101 gttgccggac agtatgaaag ggttcgcccc ggtcattcgc ggggtggcca aaagcagcgc
     2161 gcaggtaacc gttgaacaaa acggttatac catctacaaa actaacgttc cggcgggccc
     2221 attcgccatc aacgatcttt atccaaccgg cggttcgggc gacctgtacg tcaccatcaa
     2281 agaatccgat ggttctgaac agcatttcat tgtgccctac gccagcgttc cggtattaca
     2341 gcgtgaaggc cacctgaaat acgacttgac ggtaggccgc acgcgttcat cagatacgca
     2401 ttccgcgcaa cagaatttcg cagaactgac ggccttatac ggattagcag gcggcgtaac
     2461 cgcctatggc ggaatagaga gtacgctgag caatgatgtt tatcatgcgg cgctcatcgg
     2521 gacaggctta aaccttggcg atctgggcgc attgtcttta gacgtcacca actcatggtc
     2581 aaaaattaaa gcaggcgatg tggttagcga tacgcttacc ggacagtcct ggcgtattcg
     2641 ttacagcaaa gatattcagt caacaggcac caattttact gtcgccggtt accgttattc
     2701 gaccaaagat tactacgctc ttgaggatgt gctggatacc tatagcgata atagtcacta
     2761 tgatcatgtc cgcaatcgca ccgacctgtc gttgtcgcaa gacattatct acggttccat
     2821 ttcactcact ttatataatg aagattactg gaatgacact cataccacat cattaggtat
     2881 tggctataac aacacatggc ataacgtaag ctatggcatt aactattctt atacgctgaa
     2941 cgccgataat actcaggatg aagacgacga tacggaagac agtaatgacc agcaaatttc
     3001 aatcaatatt agtattccgt tagatgcctt tatgccgtca acgtatgcca cctacaatat
     3061 gaactccgcg aaagacggcg atatcacgca tactgtcggt ttaaacggca cagcgctggc
     3121 acagaaaaat ctctcatgga gcgttcagga aggttattcc tctcaagaga aagccaccag
     3181 cggtaatgtg agcgcaacct ataacgggac gtatgcggat attaacggcg ggtatagcta
     3241 cgataatcat atgcgtcgcc tgaattatgg cgttcagggc ggcgtactgc tacatcgaaa
     3301 tggcctgaca ctatcccagc caatggacga caccatcata ttggttaaag cccctggcgc
     3361 agcaggtgtc cccgtgaata acgaaacggg cgtggacacc gattttcggg gttatgccgt
     3421 cgtacctaat gcttcgcctt atcatcgtaa tgaagtgtct ttagatacga caggcattag
     3481 aaaaaatatt gagctcattg ataccagtaa aacgctggtg cctacccgtg gcgcggtggt
     3541 cagggctgaa tataaaacca atattggcta caaggcattg atggtattaa cccgcataaa
     3601 caatctgcct gttccttttg gcgcgaccgt ctcgtcttta acaaaaccag acaatcacag
     3661 cagttttgtt ggtgatgcgg ggcaagcctg gttaaccgga ctggaaaaac aagggcggtt
     3721 attagtgaag tgggggccaa cagcagcaga ccggtgtcag gtctcttatc gtataccgag
     3781 ctccccctcc gcttctggcg tagaaatctt acacgagcaa tgccagtgat tctggtggga
     3841 taaaagatga atatgaacag atttgctgca ttagccgccc tgttaacgtt cacgggtctg
     3901 gcatcatggt cgccctcgat cagcgcggca tacaataccg cagatgccgt agacattaac
     3961 gttacgggat taatttatgc cgatccgtgt accgtgacgg tacctgacac gatctctctt
     4021 gggcaatatg cccgggcgga tatcgctgtg gccggtggca ataccgccac cattcctttc
     4081 accataaaaa tgacgaattg cccggcaacg accacaaaag ccgcgatttc atttaacggc
     4141 gtaccttatc ccgatccgaa ttatgcttct gcgatttacg caaacagcgc ggccaatccg
     4201 gcgcaggatt taggattaca gctttttaac ctggacagta aaagtctggt taatctggcc
     4261 aataacgtca cttacacggt ggatatcaac agtaataccc atgaagccaa tttgcctgtc
     4321 gccgcaagga tgtatacccc gtatggaaaa gtcacggcag gggatttcac gtccgttgtg
     4381 acgatcacta tcgcatggca ataatatttt tctatttcac ctgatataaa agcaggaatt
     4441 tttcatgaga aggttatatc tggcgcttat tctgctgttc gcgtattccg gtcatagtta
     4501 cgcctcctgt aaacgttccg gtaatgaagg cgcgatcact atcaccccgc cgtcgcagct
     4561 tgtggtggat agccacgcct ataccgcagg cgaagtgttg tggcaatcgg gctgggtttc
     4621 cacctccgaa gtcacaatgg atggctgtag tcgcgattat aaggtcggtt tttatatgaa
     4681 cccggtagcg cgcagtcaaa tacatccgcg acaatcaatg cgaatgacgg gaacaacacg
     4741 ccggtattta gcaccgggat ttccggcgtg ggcattgcga ttaaaaccca aacgaatgct
     4801 ggcccttacg ataatgtcat gccaatcgat aatacgtacc ataatggcga tggcaataaa
     4861 acccaccatg cgatggcccc cgcctacaat gttgaactgg tcgccttagg cggtccgatc
     4921 acctccggta ccgcgacatt ccaaagccca ctggcacgtg tatcctttcg cgatagcgca
     4981 acggaaagct ctggcggcga tatcctgacc catctgtatt tgggtaatac gcaattgatc
     5041 atgaaagcga tgggatgtcg ggtagaaaca cctgccatca ccgttgattt aggcagcgtc
     5101 aatttaggca gtttcgctaa cagtcaaacc gcgggcacag gcaagcagga tatcttattg
     5161 acctgcgaac aaggcaccgc tatctccgca tcgttaagcg cccaaccggc cagcggaaat
     5221 aaccctgata attcagtcat ccagttgagc aatgcaagcg cgccaaccag cgcaaccggc
     5281 gttggcgtac agttgggtat tcaggcgccg gactctggtt tctttaccga cagtttgcca
     5341 atcaatcaaa aaattgatct ctttactcac acgattacca ccaatgccga tggcagccag
     5401 acggttaacg gcggaaccat gaatatgtcg accaccctga aaattagcgc gcgctactat
     5461 aaaaccgccg ccacggtaac ggccgggcaa gcgaatgcca cggcaacatt aaacctgacc
     5521 tataactgac ggcatcacat tttctggcgc tgcgcgggaa aacgttaacg cgcgcgcccg
     5581 ttagatttat ttccacaaac gtaattcgtc atcttttact ggcggtaatg acttacgttg
     5641 ctgacaagag agcgaatacc agtccagatg gcgcgtcagg aacatcacgc cgccaagcgc
     5701 cagtagcaga acgccggtac ccagaagcaa cgagctatct tccgaacgca gtaaccccca
     5761 catcacgcca tccagcgcca ataacgctaa cgtaaacagc acgctattgc gccatccttt
     5821 cagtaccgcc tgcaaataaa cgctattcat caacgcgccc actaggcttg cggcgatcca
     5881 ggctggcgtg aaaccgatat gttccgacag tgccagcaac agcaggtaga acatcaccag
     5941 cgataaccct accagcagat actgcatcgg gtgtaatcgc tgtcccgtca gggtttcgaa
     6001 gacaaagaaa gccataaacg ttagcgtaat caacaaaatg gcatatttcg tcgctctgtc
     6061 cgtcagttga tactgatcgg ctggcgtcga tacagcgacg ctaaacgccg gtaagttgtc
     6121 ccaatccacc ttttgcgcat cagcaaactg ttcgccgaga ttcgtggcaa accggctggt
     6181 ttgccactga gcctgaaatc ctgaaccgct gatttcgcgt ttaccgggaa gaaaatcccc
     6241 cacaaaattt gggtgcggcc agttactggt cagggtcatt tcactgctac gcccgacagg
     6301 aaccagtgaa aagctgccgg ttccgcttaa atttaacgac atcgccaacg tcaggttgcg
     6361 cgtcgcccac tgactgtccg gtagcgggat atgaatgccc tctctacttt ccggtaagcc
     6421 ggtccccggt tctacagtga gcatttcacc attcacctgc ggcgctttta ctgcgctgat
     6481 accgcgcgca tcgccgacgc ccacgacgat aaagggcttt ccaagggtaa tattcggtct
     6541 gttcagctca tgcagacggg ccacatcaaa ctctgccttt atcgccatat cggtatgcca
     6601 cacctgcccc tgataaatac ctatttttcg cgcttcaacg ttttgattgc cttcgaccaa
     6661 tagcgactcc ggcagccaaa aatagagata gctgcgctta tactgaacct ctttctcctc
     6721 ttccagcacg gtatagagct ctgtcaccgg aaccgccacc agcgggccga caaccttttg
     6781 cgggccgctg gtactctgac gaatagcggc ttctacatgg cttcgataat cagcacgctc
     6841 cacgatggtg tgccgtacca tcatcagggg aattaacagc aggatcatgg cgccgcctaa
     6901 cgtaatcatt ttccacaaca ggggggattt caacatagcg ttctcctttg caatgccagc
     6961 agtgtaagaa cgcgatgtgg ggagaatttg aagttatgtg aagtgacggt gaagtgtcaa
     7021 cgaggccagc acgccgcctt cgggacggtt gcacaacgtc acctcaccgt tgaggagccg
     7081 cgccgcctcg ctgacaaacg ccagcccaag cccgctgctt ttacgcccgt tttcacgggg
     7141 caacgaatag aatcggtcga aaatgcgcgg cagcgcaaaa tcaggaatac cacagccgga
     7201 atccgtcacc tgcaggatcg ctttctctcc catcggctga gcgcttaatg tgataacgcc
     7261 attttcaggc gtaaagtcga tggcattgtc caacacattg cccagcgcct gcgccagaag
     7321 ctccgcgtcg gcgacgacaa ccagcgagga aggacgtaga gtaagcgtga tcttttttgc
     7381 cgccaactga atactgcgcg cctcgctaag ctgcgtaaat agctcatcaa cagcaaccgg
     7441 cgcgagaggg atatcctgtc ggttttccag ccgcgcctgg cgcagcaggg tttctaccag
     7501 cgcctgcatt cgcgtatttt gcgccagtat attctctgta aagcgggtaa ccacatccgc
     7561 gggcggtcct tcacgcagaa tctccgccgc gccgcgtatc gccgccagcg gacttttcag
     7621 ctcatgagtc aacgcataca cgtactgctc aatgtcattc ttgccttcca gcttaatgcg
     7681 catactctcc agcgcctgcg ccagtttacg cagctcgctg ctgcctaatg caggtaacgc
     7741 aagcgggcgg ttttcggtga cggaatccgc atagcgcgtc aaccgggcga tggagcggtt
     7801 aatccaccag accatccccg cgccaatcgc cagcgcaatt cccagtaaaa cggcgctggc
     7861 ccacagaatg cgccgttcgc tgcgcttaat caccggcgcc attgccgcat tcggtttgcc
     7921 gacagtcagg acgccgatga tccgtccatc gctgattatc ggcgcggcta cgtacatcac
     7981 ggtgctattg ggatcggcag aatcttttgc cgtgctgcgg gcgccatact gtccgcgcaa
     8041 cgtaagccag acgtcattcc agcgagaata atcctgcccc accgctttgt tttccgaatc
     8101 aaacaacacc ttcccctgcg catccgtcat gtagacatgg tattcattac gcactttgac
     8161 gatcccgctg atattggcgc gaaacgggcg atgttgcagc tgggcgaatg ctttcgccaa
     8221 ctggccgtca gtcgggttgc cggaaaggag atcgtcgcgg gccagcgccg ccagcagcgt
     8281 cgcggtgtca atcagcgtcc cttccgtcgc gcggcggacg cccggcttta tctcctgaac
     8341 aaagatagac agcacaaaca cggcggcgac ggcgacaata agaaagtagc ccagcagcaa
     8401 acgcattccg atgcgcatca gatgctcctc aggctgtatc ccattccacg atgcgtgtta
     8461 attggcgaga gatccgggtt gatcgcgcgt agtttagcgc gcagggtttt gatgtgcgta
     8521 tcgaccgtcc gatcgaaggt ctcttgggca tcagaccaga caatatccat caattgctgg
     8581 cacgagtaca cgcgctccgg cgacagcagc agggttttaa ggagcagaaa ctcataacgc
     8641 gtcagcgaga gcggcgtacc aaaccaggcg atctgcgccg ccggttcatt gagatcaaaa
     8701 tgtccggtac gcaccaccgg cgacggcgca gcaaactttt tcacccggcg cagcagcgtg
     8761 cgcacgcggg cgctcacttc gcgcggcgag aacggcttgg cgacataatc atctgcgccg
     8821 atctccagac caagcaatcg atccacttca tcgctacggg cagtcaggaa aagaatcggc
     8881 agcgccggat gacgctccag caactgccga cacagctcaa agccgctgat atccggtagt
     8941 cccacatcga gaatcaccgc atctggccgt tgctgacgcg ctttttccag cgcgggcagc
     9001 ccgcgagcga atagctcaac ggtaaaccct tccagttgca gggtgtagat gagcgtatcg
     9061 gcgattccct gttcatcctc gactaaccag acctgcggtt gctgcatacg ctttccctgt
     9121 tattgtcgcc acggcatgac cggcaccgcg ctgatggcgt tcttcggcga cccgtcgacc
     9181 actttgtcgg agtaggccag atacgccagc gtgttgcgtt tctcatcata gaaacgtacg
     9241 acctgtaatg acttaaatat caatgaggtg cgttttttga aaaccacctc tccctgcgcc
     9301 ttgccgttct taattttgtc gctcagttca ataggcccga cctgctgaca agagatagcg
     9361 gcgtcagacg tatcttccgc cagccccaat ccgcctttta tgccgcccgt tttcgcccgg
     9421 ctaacatagc acgtcacgtt tttgacatca ggatcgtcaa aagcttccac cacgatttta
     9481 tggtcagggc cgaacatttt aaataccgta tcgactgaac caatttgttc cgcgcgggcg
     9541 ctctgcccca gcagcaacaa aattgagaaa agtactaagc tcttgtattt catattgtta
     9601 ccattcataa aagctatgtt gcgtaattat tagacattct aaaataaaat ggttatagat
     9661 cacaggatta gaataattac ctgtcacgtt gcctaaaaaa agcatttaag ctcaaaaaaa
     9721 acactgaatg ctaaaagaac aaaaaatgct attatcctct tacctgatat cgggtgctcg
     9781 ttgttgaaag gatggggata ttttatggat caggctggca taattcgcga cctgttaatc
     9841 tggctggaag gtcatctgga tcagccgctg tcacttgaca atgtggcggc aaaagcaggc
     9901 tattccaagt ggcacctaca gagaatgttt aaggacgtga cgggccacgc tattggcgct
     9961 tatatccgcg cccgtcgttt atcgaaatca gcagtggcgc tgcgtttaac cgcgcgtcca
    10021 attctggata ttgctcttca gtaccgcttc gattctcagc aaacctttac gcgcgccttt
    10081 aagaaacagt tttcccagac gccagcgttg tatcgtcgct ccccggaatg gagcgccttt
    10141 ggcattcgcc cgccattacg gctgggcgag tttaccgtgc cggaacatca gttcgttacg
    10201 ctggaagata cgccgctgct tggcgtcacg cagagctatt cctgctcgct ggaacagatt
    10261 tccgacttcc gccacgaaat gcgcgtgcaa ttctggcatg atttcctcgg tcattcgcca
    10321 actattccac cagtgcttta tgggcttaat gaaacgcgcc ccagcatgga gaaagacgat
    10381 gagcaggaag tattctatac caccgcactg ccgcaagagc aggccgatgg ctatgttcag
    10441 tcggcgcatc ccgtgctgtt gcagggaggt gaatacgtca tgttcaccta tgaagggtta
    10501 ggaaccggcg tgcaggattt tatcctgacc gtttacggca cctgtatgcc aatgctgaat
    10561 ctgacccgtc gtaaagggca ggatatagag cgatactacc cgtcagaaga taccaaaacc
    10621 ggcgatcgcc ctatcaacct gcgctgcgaa tttctgatcc cgattcgccg ttaacgctgt
    10681 agctcatcca atgcaggggt gtccagatgc gaaacgtccc ctgcggtttc taccacccag
    10741 ccagacgcca gccactgact ttcctggtaa tcgatacggg aaatagagca gttgcgcaaa
    10801 cgtaaccggc gttccgccca ggcgggtagt cccaggatag tactgaccag acagcccaac
    10861 gcgataccgt gactgaccaa taaaggtcgg ctgccctgcg gtagctccag acaggacgcc
    10921 agcgcggcat gaacgcgatc gctcaactcc tgcatcgatt ccccaccagg aatgcggcca
    10981 tcctgcgtgc cgttgaccag ctgacgacgc cagccctctt cttcttccgt cagcgaatcg
    11041 atctggcgct tttccagcac gcccatatcc agctcgcgca ggcggaagtc aaaggtaata
    11101 tcacacccgc acgcctgggc gataatctcc gccgtgcgtt ttgtgcggcc taaatcgctg
    11161 ctgatgatat gggtgatgcc gaggctgcgg gcgcgttctc ctacctgcat ggcctgctgc
    11221 tctccttttg ccgtcagggg actgtccgat tggccctgaa tacgtcgctc ggcgttccac
    11281 tgcgtttcac cgtggcgaac aaggtatacc tgtaacatgt ttttttccgt tatactgcga
    11341 taaattttta aaactgagct taattatgca ccaggttatc tctgcgacca ccaatcctgc
    11401 caaaattcag gcaattctac aggcatttga agagattttc ggcgaaggat cgtgccatat
    11461 tacacccgtc gccgtcgaga gcggcgtacc ggagcagccc ttcggaagcg aggaaacgcg
    11521 tgctggcgca cgaaatcgcg tgggtaatgc gcgacgcctg catccacaag ctgatttctg
    11581 gattggtcgc aaagagggcg ccattggcgt atttaccgcc ggaaaattaa cgcgctccag
    11641 cgtttactac caggcggtga tcctggcgct cagcccgttt cataacgcgg tgtatcgata
    11701 attatttgcg ctatgttgta ggcctgataa gcacagcgcc atcaggcatt tcgcggcgat
    11761 gttgccggat ggccgcttcg tcttatccgg cctacgagca aatcaggcgc ttttcagcag
    11821 tatctgctca agccaatgac gcagttcaac cggcgcggat ttcaggctgt ttgacccgcg
    11881 tgtgatggta gcgatgcccg cccccagctc ggttttcaac tcgcgctggc tcatttcgcc
    11941 acgcagcaac tcctcaataa tgcgcacgcg cgttcccagc gcttcacgct cgtccggcgt
    12001 aagcatcagt tgtaataaag gcagatgcag atcctctgca tatgcctgac ggagtaactc
    12061 cacaaaacga agccactcct gattacgttg ttcggcgata gccgatgaat aaggggaatg
    12121 ctgggtcatg ttataccgcc gtttgtactg ttacacgagt acaaatgata acataacccg
    12181 tctgcattaa taccgtcgct gccactcaga gtcgctcatt aaggcctctt tctgtcccat
    12241 aaagtggcga tagtaagcgt cataggccag aacgtttttc acgtagccgc gcgtttccga
    12301 aaagggaatg ctttcgacaa acgctacggc atcgatacgc ccggcgctat tgccaagcca
    12361 ggtgcgcacg cgtcccggcc cggcgttata cgccgccgat gcaaaaatgc ggttattacc
    12421 aaactgctga tagacatact gcaaatagct ggtgccaatg ttgatgttgg tctccggctc
    12481 cagcagttgg ccggggccgc ggtagtccgg aatcgaaaac attttcaccg tatgggtggc
    12541 cgttcccggc ataatctgca ttaaaccgct ggcccctacc ggtgatttta ctttcgggtt
    12601 ccaggcgctc tcctggcggg caatcgccat ggcatagctt tgtgagatat cttttccgcg
    12661 ggtatagcgg gtaaaaagat cgttatacgc cagcgggaaa cgctcctcca gatgatccca
    12721 cagttttccg gcgatcgtcg cctgtacgct cagatcccac cagtgctggt taaacgcata
    12781 gcgcgccagc tgcgcctgtt cagatttact acggcttttt accagattcg cccattcgct
    12841 gcgcgccgtg ttatccaggt tccagtacat cagctcccgt acacgcgcca tctccggccc
    12901 ctgcgtcaac gcgctgttta cgttggcggg cgctttatcg attttaagcg tgtactcttc
    12961 gcctaaacgc tgcgccgcga ccatcggata aaaaccgcgc ttctgcatta aagcatgaag
    13021 gatctctttc gcttcggcgt cacgaccgcg ctccagcaat aaatccgcct gccagtaacg
    13081 ccactcgtct ttctctttcg cctccatcgg caggcgggca agccaggtat tgagaccgcg
    13141 acgatcgccc atccccagcg ccatacgcac gcgccgctcg ataagcgacg tcgattgcga
    13201 gcgcataatc gcgtcatcgc gccatttcgc ctgcgcatcg gtcacatcgt tgcccatcag
    13261 tcgccaggca acgatatcgc gcagcgcctg cgtttgttcc tcattaagtt tctgcgcctg
    13321 taccagcgag gggatcatca gacgcgcatt ttccgcgtcc tggcgggcga cgctggcaaa
    13381 cgcgacttcc gccatctggc gggtaaaatc ggtggcgccg gtggtgcgtg caaaggtcaa
    13441 cacgttatta gggtcattag cgagggtaat gatcgctgag gcgatcgttt gatattccgc
    13501 cggcatctgt ccggccagca ccgtaaccag ccccgtattt ccggctttca tcgccagccg
    13561 aatacgttcc agatacgcca gcgggtcttg cttgccggag gcccgccaga cgctgaacag
    13621 tttatcgcag gcattcggct gacttttgcc ggtcagccaa aggtctttcg cgccctgcca
    13681 ggccgcttcc gtttgcccgg tactccattt cgcgtagtaa tagttacatt gcgcttccgt
    13741 ggtgccgggt ttctccgggc taaacgccag caagccgcgc cagtcttcac gacgcgccag
    13801 ctcattgacg aagcgcgatt gcagcgtacg cgcaggcgga agcgtaggat tggcgcgcac
    13861 aaactgcgtg acggcaatcg ccggttggtt catcaaatcg tcggtgatct tacggtattc
    13921 cagatacggg tagagcggat aatctttcag acccggcatc atctgctcta ccacatccat
    13981 ctggcggttg tcccaggcct gcttaatctg cgcatagcgg ttacgctgct cttccagtga
    14041 gtcggcccgc gcgaggtgac aaaaggtcaa caggcatacg ctggcggcga cgagacgcca
    14101 gacaaatggt ttggctctat ccacaagcac ttcctcaatt gttatccaat gcagcatcat
    14161 gccgcgtaat gaatttatgc taaccagtca tagccatttg cgccacgtta cggacacttt
    14221 tttactttta ttgcgagtgc gatctgctgg ctgggcttag gcagggaaaa aggctacact
    14281 tcgcctttga aatctattca ccatcacgat aaacatagag gcgaagtcca acgtggctca
    14341 attcgtttat accatgcatc gtgtcggcaa agtggttccg ccgaaacgtc atattctgaa
    14401 aaacatctcg ctgagcttct tccctggcgc caaaatcggc gtgctgggcc ttaacggcgc
    14461 cggtaagtct accctgctgc gcatcatggc gggtctcgat aaagatatcg agggcgaagc
    14521 gcgcccgcag cccggcatta agattggcta cctgccgcag gaacctcagc taaacccgga
    14581 acacacggta cgcgagtcga ttgaagaggc cgtttcggaa gtggttaacg ccctcaaacg
    14641 tctggatgaa gtgtacgcgc tgtacgccga tccggatgcc gacttcgaca agctggccgc
    14701 agagcagggc cggcttgaag agattatcca ggcgcacgac ggtcataacc tgaacgtgca
    14761 gcttgagcgt gctgctgacg ccctgcgtct gccggactgg gatgccaaag tcgaaaaact
    14821 gtccggcggc gagcgccgcc gcgtggcgct gtgccgtctg ttgctggaaa agccggacat
    14881 gctgctgctc gacgaaccca ccaaccacct ggatgccgaa tctgttgcgt ggctggaacg
    14941 tttcctgcac gacttcgaag gcaccgtcgt ggcgattacc cacgaccgtt acttcctcga
    15001 taacgtcgcc ggctggattc tggagcttga ccgcggcgaa ggtattccgt gggaaggcaa
    15061 ctactcctcc tggctggagc agaaagatca gcgtctggcg caggaagcgt ctgccgaagc
    15121 ggcgcgccgt aaatccattg agaaagagct ggagtgggtg cgtcagggcg cgaaaggccg
    15181 tcagtcgaaa ggtaaggcgc gtctggctcg ctttgaagaa ctgaacagcg ttgagtatca
    15241 gaaacgtaac gaaaccaacg aactgtttat tccaccagga ccgcgtctgg gcgacaaagt
    15301 cattgaagtc agcaacctgc gtaaatccta cggcgaccgc gtactgatcg acgacctgag
    15361 cttctcggta ccgaaaggcg ctatcgtcgg gatcatcggg ccaaacggcg tgggtaaatc
    15421 gaccctgttc cgcatgatgt ccggtcagga gcagcctgat agcggcacca ttacgctggg
    15481 tgaaaccgtc aagctggcct cggtcgatca gttccgcgac gcgatggaca acagcaaaac
    15541 cgtctgggaa gaggtgtccg gcgggctgga tatcatgaag atcggcaaca ccgaaatgcc
    15601 aagccgcgcc tatgtaggcc gctttaactt caaaggcgtc gatcagggca aacgcgttgg
    15661 cgaattgtcc ggcggtgagc gtggtcgttt gcatctggcg aagctgctgc aggtgggcgg
    15721 caacgtcctg ctgctcgacg aaccgacgaa cgacctggat atcgaaaccc tgcgcgcgct
    15781 ggaaaacgcc ctgctggagt tccctggctg cgcgatggtt atctcgcacg accgttggtt
    15841 ccttgaccgt atcgccaccc acattctgga ttatcaggat gaaggtaagg tggaattctt
    15901 cgaaggtaac tttaccgaat acgaagagta caagaaacgc actctgggcg ccgaggcgct
    15961 ggagccgaag cgtatcaagt acaagcgtat tgccaaataa acgtctgaat gccgggtggc
    16021 gcttgcgctt acccggccta caaacccagc gattccaata cgttgtgaaa ctgtaggcct
    16081 gataagacgc ggtaagcgtc gcatcaggca ttggttctta tccctgctcg cccatcatct
    16141 ctttcaccag ttccacacag cgcaaaaagc ggccatcgta atcagcctct ttaacgtgaa
    16201 cgaactcaat gttgttttct ttcagcatct cgaccagcag gttctggaac gctttgcgat
    16261 ccactgaact gcccaggctt cgcagtccgt cagctatcca cggcgtatta ttctccagca
    16321 aaatcaccag gtcgaagcga tactcgtcga tcagcgcctg gacaaacgga tgctcgcgcc
    16381 cttcgtattt tttgcaaaat gcctgggtgg tgacgaaatc ggtatcgata aacgctactt
    16441 tattcgcata tttcactgca aaatcaatat attgcgcatg acccagcgca attttatcgt
    16501 agtcggaata ctgtaacgcc atctcatcgc cgcccagatg cgaaaagaca tagtcgcggc
    16561 catattccca ggcgctggtg gtattaaaaa tattggcgag cttattgacc agcgtagact
    16621 tgccgcttga ttccccgccc agaatcgcga cggtacgcac gaaaaacggc ttcacttcgg
    16681 taggaatata ttcccagtaa cgaaacggat tttcgcggat ttgcgccccg ctgatattca
    16741 taaacgtgcg ttcaggatcg accagcaccg tctcaatccc taaatgctcc aggtactgcg
    16801 gcgcatcagc ctcttcggaa gtgtagatcc agctcggctg tattcccttc tctgccataa
    16861 acgctttaat gccgttgctc cagacgtccc agccatgcgg ataaggttcc atcccctctt
    16921 cattaaaggc gtggatgcga atattttttt ggtatttgaa ggtttgcagc aaccagcgca
    16981 ggcgatccga cacggtgggc tgctgcgaca tggcgctatc ttcaaacagc ccgcggtcgc
    17041 gcgtatcgtc atatcccata atgatgtgca actcatccac ctggctacag gcacgctgga
    17101 tcaagtagat gtgcccggta tgcaatggat aaaatttacc gaacaccacg ccaatgtttt
    17161 tctgtcggcg gggaaactcc agcccgagaa aacggtgtag cgcctccagt ttttgcgcgc
    17221 tggggctttt gattttggcg ttaagtaact gactcagata ccccttggtc ataccgctgg
    17281 cgtcagccac ctgttgcaga gtgcaacctt gctgcttaat cgcggttttg agatagtcga
    17341 acgatgacac aagagcctcc tgctggaaaa atcgcataac actgcctgac ggcgcttcgc
    17401 ttatcaggcc tacaacatca atccgtatca atccgtaggc cggataagac gcattgcgtc
    17461 gccatccggc aaattataca acatcactac atacagagaa ttataagtcg tcaaacacgc
    17521 ttaacgcatc tgcgagcttt ttaacaccga acacctgcat tccttccggc ggctttttcg
    17581 gtacgttggc ggcaggcaca atcgcccgac gaaaaccgtg tttcgccgcc tcggaaatac
    17641 gctcctgccc gctcggcacc ggacgaatct cgcctgccag ccccacttcg ccaaacacca
    17701 ccagatcctg cggcaacggc ctgtcacgca ggctggagac catcgccagc agtaaagcca
    17761 gatccgcgct ggtttcggtg actttcacgc cgccgaccac gttgacgaag acgtcctgat
    17821 ccgacatttg cagaccgccg tgtcggtgca gcaccgccag caggatagcc agacggtttt
    17881 gttccagacc gaccgccacg cgtctggggt tcgccatcat cgagtgatcg accagtgcct
    17941 gaatctccac cagcaacggt cgcgtacctt cccagacgac catcactgag ctgccggaag
    18001 tgacctcatc gccgcggctt aaaaagatgg cggacggatt gctcacttcg cgcaacccct
    18061 gttcggtcat agcgaagacg cccagctcat tgactgcgcc aaagcggttt ttgtggctgc
    18121 gcagcgtgcg gaaacgagaa tcggcgtcgc cgtcgagcaa tactgagcaa tcaatacagt
    18181 gttccagcac tttcggcccc gccagcgacc cgtctttggt gacgtggccg accatcacga
    18241 tcgccacgcc gcgcgtttta gcgaagcgcg tcaggtaggc tgccgtttcg cggacctggg
    18301 cgacgctgcc cggcgacgac tggatgtccg ccatatgcat cacctgtatg gagtcgatca
    18361 ccattagctt cggctgttct tcttccgcta tcaggcagat ctgctcgatg ctggtttcgg
    18421 agagcatatt cagattagcg gtcggcaggc cgagacggtg cgcgcgcatc gccacctgct
    18481 gtagcgactc ttcgccggtg acgtacagcg ttttcatctg ctcggcaagt ttgcacagcg
    18541 tttgcagcag caacgttgat ttgcccgcgc cggggttacc gccaatcaaa atggcgctgc
    18601 cgggtaccac cccgccgccc agcacgcggt caaactcttt aaaaccggta gaaaagcgcg
    18661 gcagttcctc aagactgatg tcagacagtt tctgcacttt tgatacgccc gcactgccgg
    18721 cgtatccgct cagacgttcg ttacgcgcca ccgtcggcga cgcggcaagg cgcacctcag
    18781 taatggtgtt ccaggcctgg caggcgctgc actgcccctg ccagcgtggg taatcggcac
    18841 cacattcatt acaaacaaag gcgcgtttgg gagcttttgc cacgttttac ctctttcgtt
    18901 aacgctgttg ccggatggcg ctggcgctta tccggcctac ggtcgccttg ccattgggca
    18961 gattaatcat ttctggttca tgctgccgga gagaatgcaa aacacgccca tcaggtcagc
    19021 gtggcggatc gtaatctccg tcttttcgtt tacttttggc ttggcatgga aggcaatacc
    19081 taaccctgcc gctttgatca ttggcagatc gttagcgccg tcgccaatcg ccaccgtctg
    19141 cgccagcggg atgtcatgct cttgcgccag acgaagcaag gtattggctt tatactcagc
    19201 atccacaata tcgccgataa cgtgaccggt aaatttaccg tccatgatct ccagctcatt
    19261 ggcgaccgcc gccgtcaggc gtagctggtc acgcagatag tcggcgaaga aagtgaagcc
    19321 gccggaggcg atagcgattt tccagccgag cgcttccagt tttagcacca actgcgttaa
    19381 tcctggcatt agcggcagat tcccgcgcac ctggcgcaaa atatcggcat ccgcgccttt
    19441 cagcgtcgcc acgcggctgc gcaggctggc ggtaaaatca agctcgccgc gcatcgcgcg
    19501 ctccgtcact tcagccacct tctcaccggt accggccagc ttagcgattt catcgataca
    19561 ctcaatctgg atcgccgtgg aatccatatc catgaccagc agccccggcg tgcgcaaatg
    19621 cggaatttta cccagcggcg cgacatccag ctgcgcctca tgcgccagcc gcgtcgcacg
    19681 cggcgtcagc gaccccgcca gacgaatgac ctgataatcc tccacgcacc aggcggcgac
    19741 aatcaccatt gccgcgccca gtttggtctg atattgagtt aaacgctgct tatccagccc
    19801 gcgcccatac agcagccaac cgctgcggcc tgcatggtaa tccagaggca tcacctcgtc
    19861 gccgcttaaa gaaagaggca aaccaggcca taaagagaca tcttcaggca gatcgcacca
    19921 ggtaatgtta ggcattaaag ctcctgtaaa tcgttcaggc cggtaaccgc cccgcggaaa
    19981 ataacgcatg aggctacctt gtaaccatcg cttctggcaa cattaagcct caaattttca
    20041 gcaggtggaa tatggctcgc gcaaaactga aatttcggct gcatcgtgca gtcattgtat
    20101 tgttctgtct cacactgctc gtcgcgctca tgcagggcgc gtcctggttt agtcaaaacc
    20161 accagcgaca gcgcaatcca cagctggaag agctggcccg cacgctggcg cgccaggtga
    20221 cgctcaacat cgccccgctg atgcgcagcg aaacaccgga tgaaaatcgc atcaacgccg
    20281 tgctgcgtca gctcacgcaa gagagccata ttctggatgc cggcgtctat gatgaacagg
    20341 gcgatcttat tactcgcgct ggcgaaagcg tcaacgtgcg cgacaggctg gcgctggatg
    20401 gcaaaaaagc gggcagctat tttaaccaac aaattgtcga gcctatccag gggaaaaacg
    20461 gcccattggg ctacctgcgt ctgacgctgg atacccacac tctggccacc gaagcaaaac
    20521 aggtcgataa caccaccaac attctacgcc tgatgctgct actctcgctg gcgataggcg
    20581 tggtgctgac gcgcaccttg ctacaaggta aacgcacccg ctggcagcag tcacccttcc
    20641 tgttaacggc cagcaagcct gttccggaag aggaagagcg tgaggaaaaa gagtaaaatg
    20701 acggcttaat aaaggtaagg aaaaccacca tgacaacatt acgcctgctt atttctgact
    20761 cttacgatcc ctggtttaac ctggcggtcg aggagtgcat tttccgccag atgcccgcca
    20821 cccagcgcgt gctgttcctg tggcgcaacg cggacacggt ggtcattgga cgcgcgcaaa
    20881 acccgtggaa agagtgtaat acgcggcgta tggaagaaga taacgtccgt ctggcccgcc
    20941 gtagcagtgg cggcggcgcg gtattccatg acctcggtaa tacctgcttt acctttatgg
    21001 ccggtaaacc ggaatacgat aaaaccatct ccacccatat tgtgctcgcg gcgctgaatt
    21061 cgctgggcgt catggccgat gcttcaggac gcaacgatct ggtcgtaaaa acgccggacg
    21121 gcgatcgcaa agtctccggt tcagcctatc gcgaaaccaa agatcgcggc ttccatcacg
    21181 gtacgctgct gctgaacgcc gacctcagcc gtctggcaaa ctatctgaat ccggataaaa
    21241 agaaacttgc ggcgaaagga atcacctccg ttcgctcccg cgtagccaat cttaccgagt
    21301 tattaccggg tatcacccat gaacaggtct gccaggcggt cacggaagcc tttttcgccc
    21361 attacggcga acgcatcgac gcggaagtga tttcaccgga taaaacgccg gatctgccga
    21421 attttaccga aacctttgcg cgccagagca gttgggagtg gaatttcggc caggcaccgg
    21481 cgttcagcca tctgctggac gagcgtttca cctggggcgg cgtcgagctg cattttgacg
    21541 tagagaaagg tgtgattact cgcgcacagg cgtttaccga tagcctgaac ccggcaccgc
    21601 tggaagcgct ggcggggcgg ctgcaaggct gccagtatcg ggcggataaa ctacaggaaa
    21661 cgtgcgaagc gctgatagcg acgtttccgg aacaggagag tgagttgcgg gaactggcga
    21721 attgggtcgc aggggccgtg cgttaaagaa ttgccggatg gcggctacgc cttatccggc
    21781 ctacaaatga gtgctttctg taggccggat aagcaacgcg ccatccggca ttaccgctat
    21841 tcaccagcgt caagatccct cacctccccc gcccaatcaa ccgggtaaac gccattgcga
    21901 acatcacgat gaaaggtcga aaacggccaa tcctgcaccc gccttaccca accgtgcttc
    21961 acggggttga agtagaggta atcgacatgt cggcgaaaat ccttttcgtc gcgaatcgtg
    22021 tgctcccaga atcgtggctg ccacacgtca tggcgcatta tcgatttggt aaataacttt
    22081 ttaagctccc gccagcgaga tgaaaagtca caatcgttct caggaagcgt ccagatgcaa
    22141 tgcagatgct caggcaacac gacaaaagca tcaatttgaa aaggcttcgt atttttcact
    22201 cggcgaatcg cagagcgtaa ttccgcaatc tggcggacaa gtaaatcact tttccggttt
    22261 ttcagattaa ccgtgaaaaa ccaggttcca ccgttaatgt aataacgacg atagttcgac
    22321 attttgttca ttccttaaac aaaatccaaa cgtaacgggt taatagcaaa aggcaatgcg
    22381 gagagggtaa ttcgggaatg aggctcgcag tataaacagc agattgccgg atggcggcta
    22441 cgccttatcc agcctacaaa tcgatcctgt aacaatcgca ggccgttgta ggcccggtaa
    22501 gcgaagcgcc accgggcaca gcacaatctt actctttatc gcccagcagt acggattcca
    22561 gcgcgatttt gatcatgtcg ttgaaggtcg tctgacgttc agcggcagtg gtctgctcgt
    22621 gggtacggat atggtcagac acggtgcaga tggtcagcgc tttcgcgcca aattcagccg
    22681 caacgccgta gatacccgcc gcttccatct ctacgcccag tacgccgtat ttttccatca
    22741 cgtcgaacat ttcgccgtcc ggagaataga acagatccgc ggagaacagg ttgcccacgc
    22801 gcgcgtctac gcccagcgct tttgccgcgt caaccgcgtt acgtaccatg tcgaagtcag
    22861 cgatagccgc aaagtcatga tctttgaaac ggatacggtt cactttggag tcggtgcagg
    22921 cccccatacc gatcaccacg tcacgcagtt tgacgtccat gcgcacagcg ccgcaggagc
    22981 cgacgcgaat gattttcttc acgccgaaat cggtgatcag ctctttggtg tagatggagc
    23041 aggacgggat acccataccg tggcccatca cggagatctt acggcctttg taagtcccgg
    23101 tgaaacctaa catgccgcga acgttgttca cttcgcggac atcttcgagg aaagtctcag
    23161 caatgtgctt cgcacgcagc gggtcgcccg gcatcaatac gacgtcagcg aaatcaccca
    23221 tttctgcatt aatatgtgga gttgccatct tcagttccct ttaaatttgt tgttattgcc
    23281 tgatggcggc tacgccttat caggcctaca aaacgtgtgt aaaaacagtg aaatacccta
    23341 aggatttcgc gttgtaggaa ggcgacgaat tcgtgaatcc ccgggagcat agattaacta
    23401 tgtgaccggg gtgagcgaat gaagtcaacg catctacagc gcgaaagaca acgggtatca
    23461 cagcatgttt ttaccgtagt ccatcggcga tgtaccaaag taggtcgcca gcgtctggcc
    23521 gatatccgca aaggtttcac ggtgacctaa agagcccggt ttgactttcg gaccgtagat
    23581 cagcaccgga atgtgctcac gggtatggtc agtaccggtc cagctcgggt cacagccgtg
    23641 gtcagcggtc aggatcagaa tgtcatcttc acccaccagc tccatcagct ccggcagacg
    23701 gcggtcaaac agctccagac ctgcggcgta gcccgcgatg tcgcgacggt ggccccagga
    23761 agagtcgaag tcaacgaagt tagtgaaaac gatggtttta tcgcccgctt ctttcatctc
    23821 tttgagggtc gcgtcgaaca gcgcgtccag accggtcgct ttcactttct tagtgatgcc
    23881 gcagttggcg tagatgtcgg caatcttacc gacggacacc acgtggccct gtttttcatc
    23941 gaccagtttc tgcagcacgg tcggcgctgg cggttctacg gccaggtcgt gacggttgcc
    24001 ggtacgctgg aagttaccgg ccttgtcgcc gataaacgga cgcgcgatca cgcggccaat
    24061 gttgtagccg ccttcggtca gctcttcacg ggcgatttcg cacagctcgt agagtttatc
    24121 caggccaaag gtctcttcgt ggcaggcaat ctggaacacg gagtcagcgg aggtgtaaaa
    24181 aatcggcttg ccggttttca tgtgctcttc gccgagctgg tccagaatga ccgtaccgga
    24241 agagtggcag ttaccgagat agcccggcag gttggcgcgt tttaccagct tatccagcag
    24301 ttcctgcggg aagctgtttt cgtggtcgct gaaatagccc cagtcgaaca gcaccggcac
    24361 gccggcgatt tcccagtggc cggacggcgt atctttgccg gaggacagtt cgtgcgccca
    24421 tgcgtatgcg ccaataacgt ccgcgttgcc gtccatgccg gcggcaattt taccggtaga
    24481 gccttcatgc gctttcacca gccccagacg agtcaggtta ggcagattca acgggccctt
    24541 acggccattg tcagcttcgc ctttggcgca agcttctgcg atgtggccca gagtgtcgga
    24601 acctacgtcg ccaaaacgat ccgcgtcttc agtagcgccg atgccgaatg agtccagcac
    24661 cataataaat gcacgtttca tatcttctcc gtacttagtg cttcaaaaat aattgatcag
    24721 atcagtatac aactattcag taattcgacg atagaccgaa ggtgtgcttg ctggcgcttt
    24781 atcgtcaagg ataattgccg ctttgacggc cttcgccgct tcctgccaac tggcttcgtc
    24841 tttggcatga atcaccgcca gcgggcgctg cccgtcgatg ctgtcgccca gacgggccat
    24901 gtcggtaaag ccaacgctgt aatcaatggt atcagacgcc tgacgacggc cgccgcccat
    24961 cgagacgacc gccatcccca gcgcacgcgt atccattgcg ctgataaacc cttcggtatc
    25021 agcatatacc gctttgctca acatggcggt cggcaggtat ttatcgtagt tctcaacgaa
    25081 atcgctcggc cctttctgcg cggccaccat acgaccaaag acttctgccg ctttaccgtt
    25141 atccagaacc gcctgtaatt tcgcacgcgc ttcggcgtcg tctttcgcca gctggccgga
    25201 gatcagcatc tccacgcata gcgccatggt aacgtcaaac aagcgcggat tgcggtattc
    25261 tccggtcagg aactgcacgg cttcacgcac ttccaccgcg ttaccggcgc tcgaagccag
    25321 cacctggttc atatcggtta acaaagccgt agtgcgaact cccgcgccgt ttgccacgcc
    25381 aacaatcgct tcagcaaggg cttcagaaag ttcataggtt ggcataaacg cgccactgcc
    25441 gactttgacg tccattacca gcgcatccag cccttcggcc agtttcttgg cgaggatgga
    25501 accagtgatc agcggaatag agtccaccgt cgcggtaata tcgcgggtgg cgtaaaaacg
    25561 tttgtccgcc ggtgcaagcg agctggtttg cccaataatc gccacaccca cgtcttgaat
    25621 aatttcgcgg aaacggttgt cgtccgggaa gatgtcgaag cccgggatcg cttccagttt
    25681 gtcgagcgta ccgccggtat gtccgagacc gcgaccggag atcatcggca cataaccgcc
    25741 gcaggccgct accattggcc ccagcatcag agacgtcacg tcccctacgc cgccggtcga
    25801 atgcttatcg acaatcgggc cattgagatt caggcttttc cagtcaagga cagtaccgga
    25861 atcccgcatc gccatggtca gcgaaacacg ctccggcatg gtcatatcgt ggaagaagat
    25921 ggtcatcgcc agggcggcaa tctgcccttc agagatagta ttgtcacgaa taccattgat
    25981 aaagaaacga atttcttcgt cactcaacgc atgaccatca cgctttttac gaataatttc
    26041 ttgtgcgaga aacacggtac cctcctgagg gaaaagagta gaaggcttac atcgccggat
    26101 ggcggctaac gccttatccg gcctacaggc ctggatttgt aggccggaaa gcgcagcgcc
    26161 atccggcaaa tcagagctta gtagctgctg gcgctcttac cgtcgccgtg acccagcgct
    26221 ttcagcaggc ttgccagcag gctggatgcg ccaaagcggt agtgacgaga atctgcccag
    26281 ttagcgccaa acagttcgtc tgcgatcgcg aggaatttct gcgcgtcttc cgccgtacgt
    26341 acgccgcccg ccggtttgaa gccaacggtt ttggaaacgc ccatgtcgcg gatcacttcc
    26401 atcatgatgc gcgcgctttc cggcgtagcg tttaccggca ctttaccggt agaggttttg
    26461 atgaaatccg caccggcttt aatggagatt tcagaggctt tacgaatcag cgcctcttct
    26521 ttcagctcgc cggtttcgat aatcactttc agcaatacgt tcgctgcggc acaagcgtct
    26581 ttacaggctt ttaccaggtc aaaacccacc tgctcgttac cggcgatcaa cgcgcggtac
    26641 gggaatacca cgtccacttc gtcagcgccg taggcgatcg ccgcacgggt ttccgccagc
    26701 gcaatatcga tgtcatcatt gccatgcggg aagttagtca ccgttgcaat gcggatgtcc
    26761 ggggtacctt gttctttcag agttttacgc gcaatcggga taaaacgcgg gtaaatacaa
    26821 atcgccgccg tattcccgac cggggttttt gcctgatgac acaacgcgat cactttttca
    26881 ttggtgtcgt catcgttcag agtggtcaga tccatcagtt tgagcgcacg caggctgctt
    26941 gcttttaaat cagtcatgac attctccaac ggcattgccg tataaaattt caccttgcga
    27001 gtctgttaat attctaacat tcactcgcga ttacacttcg atatacatca cagttaatga
    27061 aaactacgta caaatttgca ttactgtaat gagatctgaa tcaaattatc ccgccgtcac
    27121 cgcctgttct tcgagcgtta agcgcatcag gatcaaagtc ggtttgccgc cattttctac
    27181 aatagcgcat cgtcccggca taaagaggaa acgaagatgc ctgcctcatg cgaaactgcg
    27241 ctccagcagc gttgccagca aattgtgacc agcccggtgc tcacgcctga acaaaaacgc
    27301 cattttctgg cgctggaagc tgaaaacgcc ctgccttatc ccaccctgcc ggaagatgcc
    27361 cgccaggcgc tggatgaagg cgtcatttgc gatatgtttg aggggcacgc ccccttcaaa
    27421 ccgcgctacg tgttgcccga ttacgcccga tttctggcta acggttcaca gtggctggaa
    27481 ctggaaggcg cgaaagatct ggatgatgcg ttatccctac tcaccattct gtatcatcac
    27541 gttccttccg tgacgtccat gccggtttat ctcggccagc ttgatgcgtt gctgcaaccg
    27601 tatgttagaa ttctaacaca agatgcgatc gatattcgaa taaaacgttt ctggcgttat
    27661 ctcgacagaa cgctgccaga cgcctttatg catgccaata ttggccctgc cgatacgcct
    27721 gtcacacgag cgattttgcg cgccgatgcc gagttaaagc aggtggcgcc taacctgacg
    27781 tttatctacg atgcggaaat tacgccggac gatctgctgc tggaggtcgc caaaaacatt
    27841 tgcgaatgca gtaagccaca catttccaac ggccctgtaa atgataaaat tttcacaaaa
    27901 ggccattatg gcatcgtcag ttgttataac tcgctaccgc ttgccggcgg tggcagtacg
    27961 ctggtacgtc tcaacctgaa agccgtggca gaacgcagta cgtctgtcga tgacttcttt
    28021 tcacgcacgc taccgcacta ctgccgacag cagatcgcca tcattaattc acgatgtgaa
    28081 ttcctctatg aaaagtcaca tttctttgag aatagcttcc ttgtacagga aggtttgatc
    28141 gatcccgaac gttttgcgcc gatgttcggt atgtacgggc tggcggaagc cgtgaacctg
    28201 ctgtgcgaaa acgccggcct gaccgcccgt tacggcaaga atgaaacggc gaacgagctg
    28261 ggctaccgta ttagcgccca actggcggat ttcgtcgaaa atacgccagt gaagtatggc
    28321 aggaagcaac gggcgctgct ccatgcccag tctggcatca gttccgatat cggcactacg
    28381 ccgggcgcgc gtctgccgta tggcgatgaa ccggacccta tcacccattt gcaaaccgtc
    28441 gcgccgcacc atgcctttta tcatgccggg atcagcgaca ttctgacgct ggacgaaacc
    28501 atcaagcgca atccgcaggc gctggttcag ctttgtcttg gcgcgttcaa agccgggatg
    28561 cgggaattta ccgccaatgt cagcggcaac gatctggtgc gcgtcaccgg ttatatggtg
    28621 cgcctgtcgg atctggcgaa atttcgcgcc gaaggctcgc gcacgaatac cacctggctg
    28681 ggagaagaag ccgcacgtaa tacccgcatc ctggaacgac agccacgcgt agtcagccat
    28741 gaacaacaga tgcgctttag tcagtaagat cattgcgttt tcctgcgtcg atgggccagg
    28801 cagccgcctg gcattattct tacagggctg caatttgcgc tgcaagaatt gccataaccc
    28861 gtggacgatg ggacgctgta acgactgcgg ggaatgcgta tcgcagtgtc cgcaccacgc
    28921 cctcagcatt gatggcggga aagtggtatg gcggtcggac gtctgcgagc agtgcgatac
    28981 ctgcctgaaa atgtgcccac agcaggcaac gccaatggcg cagactatga gcattgacga
    29041 tgtgctgcgt catattcgta aagcatcgct gtttattgaa ggtattaccg tcagcggcgg
    29101 agaggcgacc acgcaattac cgtttattgt ggcgctattt acggcgctca aagccgatcc
    29161 gcagttacaa cggctgacct gtctggtgga cagtaatggt cagttaagcg agaccggctg
    29221 gcaaaaacta ctgccggttt gcgacggcgt aatgctcgat ctgaaagcct ggaagagcga
    29281 gtgtcatcac cgtctgaccg gacgtgataa cacgcatatt aagcacagta tccgctttct
    29341 tgctgcgcgg ggaaaactgg cggagctgcg gttgctggtt atcccgggtc aggtggacta
    29401 tgcggcgcat atcgattcac tggcggcgtt tattacttcg ctgggcgagg ttccggtgcg
    29461 cctgaatgcc tttcatgcgc atggcgtcta tggcgaagcg aaagcctggc caggcgcgac
    29521 gccgcaagag gtggaacggc tggctgacgg attgcgcgcg cgtggggtgg cgaagctgat
    29581 tttgccggcg ctatatttgt aagcgtcgcc tgccggacgg cggctgcgat gccatcagag
    29641 ccgaaacaag gtaacggtat tgcgatacag cgtatcggct atcacctctg cgggctccgg
    29701 acgtaattcg cagagcgcat caaatacgcg cgccgcctgc tccgggcggt tcggctgccc
    29761 ctgaaacccc tttagcggca tatccggcgc atcggtctcc agcaacagcg cgtccagcgg
    29821 caaccgcgcc ataacatcac gggttttact ggcgcgcggg taggtgatgg tgccgccgac
    29881 gccgatttta tagcccagtt gcacaaaacg ttcggcctgt tgcagactgc cggaaaaacc
    29941 atgcaccaca ccggtttgcg gcaaactctg gcgctttaag cgcatcgcca gtttgtcatg
    30001 cgtgcgccgc gagtgcagga tcaccggcag atcgtagcgt tttgccagtt gcagttgcgc
    30061 gtctaaaaat cgctcttgcc tggcgaactg cggatcgtcg cgataaagat cgagaccgat
    30121 ctcgcctacc gccacgacgt tctgttgttg cgccagcgct tgttgcagct tatcaggatc
    30181 gtcatcggca tgacgctcaa tcacaatggg gtgcaatccc agcgcagcat aaagcgacgg
    30241 gaaacgcgcc gccagcgcca gcacgcgggg aaagtgagcc gcctcggtcg ccggcacgat
    30301 gattttttca acgcccgcct cacaggcacg ctgaatactg gcgcgctcat cgcccgtaaa
    30361 gggcgggaaa tcaaaatggc aatgcgtatc gataaagcgc cagctcacgc cagatcctcg
    30421 tcggtaaatg tggtgtcgtt tgcctgcggc gcgctaatga cctccgccac atgcgtatca
    30481 ttggccaccg gtgccggagg cacgaccacc gtttccggca cggcaatccg cgacgaatgg
    30541 cgcaagagag gcggcgttgc ggcgagcaat ttaccaacgg tggcaaggaa ataacgcccg
    30601 cataattgcc cggttttgta atcctcacgc agcgccggga tacggctgcc cagcgccatg
    30661 ctgtgcagcg gtttcggcgg ataaatttca atgatccgca gcttacccgg cggcttttca
    30721 ataaattgtt ggatcgcgct gtaggacgtt tcatgatgct gcaccaggtt gaccaacggc
    30781 tgtagactgc tctctcccag ccagcgctcc atacgcttaa accactgcgg cgtgtaatac
    30841 atttgcgagg gtacggtgcg gatcaccaca atggttttcg ccccccgctt tgccgcctcc
    30901 tgaaccggaa tggcgtcgct aatgccaccg tccagatagt tgatgccctc taacgtaacg
    30961 ccggtacggt agaaacccgg tatggcgctg gaggcgcgaa tgatatcaag ccagttttgt
    31021 tttgtcggcg agaaatagcc cggcgtgtaa tcatcccccc ggcaggcgca catataaaag
    31081 gattttccgc tgtcgaacag gcgcgctgag gtatccatct gcagcggcat ccgggcggcg
    31141 gtggactcca ccagccagtc gaggtcgata aggtttcctc cgcgtacaaa tcgcagcgga
    31201 tcaaaaaatt cgcgcctggt ggtatagcgc ataatgactt tacgcccgta gccgggctgg
    31261 ttgcagagat acgccgagag attttgcgca ccggctgatg tgccgaagta gagatggaaa
    31321 ggattaaact gcgcacgcat aaactcatcc agcacgcctg cggtaaagat gccccgctgc
    31381 cccccgccct cacagaccag cgccatacgg cctgaccgga acggtgttaa tgataacggc
    31441 gcaatattgc cgagcgtaac cggtattcgc tggcccacct ctgccttcct gtttttcatt
    31501 tttttccagg ctgacaaggt aatgcaaaac gttaacggct aaaaccgtaa aagccagtcc
    31561 gctggactgg cttgatagca atatatcttt acagctgcct gctagggtcg tttacggccc
    31621 atgaacaggc tgaccaggaa gagcacgatc ccgacgacga agacgatttt cgccgcgccg
    31681 gcagccgtac cagccagtcc accaaaaccc aatgcggcgg caattaacgc gataaccaga
    31741 aatataatgc cccaacgaaa cataagcctc tcctttacca tagttaatgt cgaccgctaa
    31801 atatgagcgc tcaggctact cattcgcgat atttttagtg tggtgcacat tacgcctccc
    31861 gacaaacgtc gggaggacga attacgacga attactgaac tttcagatcg tttttaacac
    31921 tttttacgcc atcaacggct ttcgcgatgc tttcagcgcg gtcgctttgt tcctgagttt
    31981 caacagtacc ggagagctgt acgacgccat cggtcgtttc cacttttact ttacgggaag
    32041 ggacgagatc gtccgccagc aacttggctt tgacttcact ggtcgtggcc gtatcgccgg
    32101 cataaccttt cacggaacct tctttattgt cgcgaacgtg aagtttgtcg ctaacggagg
    32161 tcacgccttc tacgcctttc gccactttca cggcggcttc agcctgcgcc tggctttcta
    32221 caaagccgct cagggtgacg actttctgat tggtttcgac agaaatatcg gtgcttttaa
    32281 tattgtcatg gtctaccagc gcagctttga ctttcgcagt gatagcgctg tcatccatga
    32341 agttaccgac tttattcata gagctatcga ctttttgccc tgcggtttcg gttccgcttt
    32401 gcgccttgtc cgttgttgcg ttttctgcaa aggcagaacc tgtcgcaaca gcagaggtca
    32461 acattacggc cagcagagtt ttagaaatct tcagtcttgt catagtcatc gattttgtcc
    32521 tgtatagttt gctcgtaatt tgagctcagg caacacgagg ttgcattgct gaatgcggtg
    32581 aaactcaccg gtttctgaag tcaatgactg gcatcacatt cgtgaatttg taacgacgcg
    32641 tcgcctgcca cccttccgtt tcagttatta atatcgtgac tgaaacaaat ctcagcttta
    32701 agctctcata ttcacgcatt gaacaggcat taaagccgac atttatgtca tcactttgtt
    32761 aaatatagat cacaatttta aaatcgcttg tcggtgcgta taaaaaacag gcagatcgga
    32821 gaaaaaacgc gggatttaag aacattccgt aagcggttaa aaaggcaggg aaagtacgaa
    32881 ggcgcggcgg atgccgcgcc cggaaaggga tcagtgttcg cgcgttttac ggaactgaac
    32941 gtcagggtaa cgttcctggg tcaggttcag gttaaccatc gtgggggcga tataggtaag
    33001 gttgtcgccg ccatccagcg ccagctgcgt ttcattctta cgcttaaact cttcgaattt
    33061 cttcgcatcg gcgctttcca cccagcgcgc cgtcgccacg ttgacggatt cataaatcgc
    33121 ctcaacgttg tattcgcttt tcaggcgcgc gacaacaacg tcaaactgca aaacgcccac
    33181 ggcgccgaca atcagatcgt tgttggagat gggacggaat acctgcaccg ccccctcttc
    33241 agaaagctgc accagccctt tcagtagctg cttctgcttg agcggatctt tcaggcgaat
    33301 acgacggaac agttccggcg caaagttcgg gataccggta aacttcatca tctcgccctg
    33361 ggtgaaggta tcgccgatct gaatggtgcc gtggttatgc agacccaaaa tatcgcccgg
    33421 gtacgcttct tcaacgtgcg aacggtcgcc cgccataaaa gttaacgcgt cggaaatcac
    33481 cacatctttg ccggtacgga cctggcgtag cttcatgccc ttctcatact taccggaaac
    33541 cacgcgcata aacgccacgc ggtcgcggtg tttcgggtcc atattggcct gaattttaaa
    33601 gacaaaaccg gtgaacctct cttctgaggc ttccactgtg cgggtatcgg tttgacgcgg
    33661 catcggcgcg ggcgcccacg ccactaaacc atccagcata tggtcaacgc caaagttacc
    33721 cagcgcggta ccgaaaaata ccggggtaat ttcccctgcc aggaacagct cttcatcaaa
    33781 ctcgttagat gcgccctgca ccagttccag ctcgtcgcgc agttgctgcg ccaggtcttc
    33841 accgacggcg gcgtccagat ccgggttatt cagcccttta acgatgcgca cttcctgaat
    33901 ggtgtggccc ttaccggtct gatacagata agtttcatct ttataaaggt gataaacgcc
    33961 cttaaacagc ttgccgcagc caatcggcca ggtgatcggc gcacagccga ttttcagctc
    34021 attttccact tcatccagca gctccatcgg gtcgcggatg tcacggtcga gtttgttcat
    34081 aaaggtcagg atcggcgtat cacgcagacg ggtaacttcc atcagcttac gagtcctgtc
    34141 ttcaacacct tttgcggcgt cgatcaccat cagacagcag tccaccgccg tcagggtacg
    34201 gtaggtatct tcggagaagt cttcgtgccc cggggtgtcc agcaggttca ccagacaatc
    34261 gtgatacggg aactgcatca ccgaggtggt gatagagata ccacgctgtt tttccatctc
    34321 catccagtca gattttgcat gttggctgga gccacggcct tttaccgtac cggcggtctg
    34381 aatcgcctgt ccgaacagca acactttttc ggtaatggtg gttttaccgg cgtccgggtg
    34441 agaaatgatg gcaaaagtgc ggcgtttggc cacctcttgc aaataaggag acaacgtcat
    34501 agtcaaatct tcttgagtaa gcgcggcgtt tgaccacgca tgttgaatac gaaaaatgcg
    34561 gctattttac ccatcaacct gggggaggca atcagtgttt acacaggagc tgctccagtt
    34621 cgcttaatga cgccacagtc caggttggat ggatacccgc gggctgctcg cgatgatgcg
    34681 cgttaagcca gcaggtcgac agtccggcgt taatgccgcc aagaatatcg gactccgcgg
    34741 tatcgctaac cattaatacg cgcgagcggt caggattccc cgcctgctcc agggcgtagt
    34801 taaagatttt cggatcgggc ttcgcgacgc caacctgctc ggaaatcacc agcagatcga
    34861 aatactcgcg cagcccggtg cgctccagac gagtttgttg tagcgcggta aaaccgttag
    34921 taataatacc gattttagcc tgcccgcgaa tcgcattaag tagcgaaacg gcgcccggca
    34981 aaggagaaca gatctccgcc atcgcactaa taaaagcgtc attcagccgc cccggcgcaa
    35041 cgtttagccg ttcagcccaa ctttgaaagc gcgcgtgctg caattgtaat gaagtaatcg
    35101 cgccgttctg ataatccacc catagcggct tattcacggc ctggtaatcc tggaaatcct
    35161 cagcggtaaa ggtgacgcta tagtcaagga acatccgctg taagccggtg aaagaatcaa
    35221 acgtaaacag cgtttcatcg gcatcaaaga aaatccagtc ccacttcatc attacacctt
    35281 gcctctttta ttacatgctt atcggtaacg ccatgatgat ggcgtcctca tgcccttgtg
    35341 ccgtgggata gtaattgcgg cgaatcgtcg cctcgttaaa ccccagactt tcatacagcg
    35401 cgatggcggc agcgttagag gcgcgtacct ccagccataa cgttacaaca ccgcgttttt
    35461 ccagttcatc aatcagatgc tcaagcagca tacgccccag cccccgacgc tgaaaatccg
    35521 gatcgacggc gatattgaac agcgtcgctt cgtccagcac cacctgtgta atggcaaacg
    35581 cggccattct gtcatcagca gtcagcttaa agttgagata ccgttcgccc tggttgccga
    35641 aaaacgtttt ttcgctccac ggaaacgcat gagcgcgttg ctcaatctgc caggctgcgg
    35701 ggagatcggt cgtgctgagg atagaaatcg tgttcatgtt cgcagatttg ttgccatagt
    35761 gcggcgcgtg ccgccgggtt tacccggagt tcattaaacg ccggcgtcgt gacctgagcg
    35821 ccttcgagtt ggagcggcgc gtcagttcct aaccgccagc tattacaacg gctgccctgc
    35881 ggcagcatgg cgacgcgctc aggcgtcagc ggtaaaacct gatcgggact cacggtcaac
    35941 gcgcgtaaaa tatcgcgcat tagcggctcg ttcagcgcgg gtaattcctc tgcaaccacg
    36001 atcagacgaa cgtgcgcggg aagggaaatc gcaatctcgc cctgtagcgc gccaggacgt
    36061 cgcagcgccc actgcgtaat acccagttgc tgtaactgcc agtctcgtcg ggatgtcata
    36121 gcgaaacgct cctgtaatca ggggcgcaaa tatagcaaat ctgtcgaatc tccgccatca
    36181 aactactata atcgccgcca gtctgaatta aggagcattc catgtctgct tttaccccgg
    36241 caagtgaagt cttgctgcgc cacagtgatg atttcgaaca aagccgtatt ctttttgccg
    36301 gagatttgca ggatgacctg cccgcgcgct ttgaatgcgc cgccagccgc gcgtatacgc
    36361 aacagtttca ccactggcag gcgttaagcc gccagatggg cgataacgtc cgttttagcc
    36421 tggtcgcgca agccagcgat gtcgctgact gcgatacgct gatctactac tggccgaaaa
    36481 ataaacccga agcgcagttc cagttgatga atattttgtc gctgatgccg gtgggcagcg
    36541 atgttttcgt cgtgggagaa aaccgcagcg gcgtgcgtag cgccgaaccg atgctggcgg
    36601 actatgcgcc gctgaacaaa gtagatagcg cgcgacgttg cggcctttac catggtcgtc
    36661 tggaaaagca gccgcagttt agtcttgaat cctggtgggc cgagtacaat atcgacgggc
    36721 tgaccatcaa aacgttgccg ggcgtattca gccgcgacgg actggatgtt ggtagccaac
    36781 tgctgctgtc tacgctgacg ccgcacacca aaggtaaagt gctggatgtc ggctgcggcg
    36841 ctggcgtgct ttccgccgcg ctggccagcc attcgccgaa agtgcgcctg acgctgtgtg
    36901 acgtcagcgc gccggcggtg gaagccagcc gcgccacgct tgccgctaat ggtcttgaag
    36961 gcgaggtatt cgccagcaac gtcttttcgg aagtcaaagg acgttttgac atgatcatct
    37021 ccaacccgcc gttccacgac ggaatgcaaa ccagccttga tgcggcgcaa acgctcattc
    37081 gcggcgcagt gcgccatctg aacagcggcg gagagttacg catcgtggcg aacgcctttc
    37141 tgccctatcc taagattctg gatgagacct ttggcttcca tgaagtcatc gcgcaaaccg
    37201 ggcgctttaa ggtttatcgt atcgtgatga cccgtcaggc gaagaaatag ttggcctgat
    37261 aagcgcagcg ccatctggtt gcatgtgccg gatggcgacg ccaggcgtct tatccaacct
    37321 acgtctcgcg cccatttttg cagcaatcaa tctatcccat gcaattaact attgacgaat
    37381 agctgaaaac cactagaatg cgcctccgtg gtagtgattc ttttcaagaa tcgatggtat
    37441 gcgaaggtgg cggaattggt agacgcgcta gcttcaggtg ttagtgtcct tacggacgtg
    37501 ggggttcaag tcccccccct cgcaccaaaa ccatgttgat attgctcgca ctgggcgaag
    37561 gtggcggaat tggtagacgc gctagcttca ggtgttagtg ttcttacgga cgtgggggtt
    37621 caagtccccc ccctcgcacc aacgaggcga tatcaaaaag taagataact gtgcgaaggt
    37681 ggcggaattg gtagacgcgc tagcttcagg tgttagtgtc cttacggacg tgggggttca
    37741 agtccccccc ctcgcaccaa ttatcttatc cttcctttgt cccttcattt tcatccctga
    37801 ttccagttca tcattgccaa catcatgccg ccaataagcg ctatacacga tggcagcagt
    37861 acaaaatgcc gtaattgttt gtgatacaac atcagcgcag acagtagcaa tcctgataca
    37921 atcaacagct tcagcgcata agctgacagg ccgataaacg ccagtccaac gataatcact
    37981 ccaggcaata acacgcccca tccgctgcct aacgtccgct gcaacatggt ttcacctctg
    38041 gaattgataa tgataaccaa tatcatatga tatattttct catttgtcag ccagggagaa
    38101 agctaaagag atgagtttta cttaacggtt gatgacacgt attcagtaag gtgataaatt
    38161 gtccgactgt taacgtaaaa acaacaacac ctcgctttag gcgacctttt ctcatacgtt
    38221 attttcatgt tggcgcccga ttccgtgtat atcactgata aataacgaca attacccatg
    38281 acaacaccat cctggcgatc gcttcgtatt aagaagtatc agttttcttt acgtcttttc
    38341 ttgtttctca gcgccgtgtc ggcgctattt actctcgttt tcccccttta tcagatcaat
    38401 gtattttgca cgccaatgat cgggatagtg ggcctgagcg tattactgtt gatatggcat
    38461 gggaaatatg ggcaaaaaag aattaacctc ccctttatct ccctactctt tgggggaata
    38521 tgggcggcgc gtattgcgct aaagtatccg gcgttaggcc attatgattt ctctttttta
    38581 ctgatctccc tgcttagcgt tctgtttatc ggctcgatag cctttgccgc gaatatcgtc
    38641 gcgtttacgc tctattcgct accgccagtc gcggtctgcc tgtggttgaa cggtaatgaa
    38701 caaggtttgc gaattctcta tttgctggcc ctgccaatgg tgggaatcgc tattcaacat
    38761 gttatccaga aacgctacga taattttgcc caacagctca tgtttaagct gctggccgag
    38821 cgggaaaccc tcaatggcct gagtatgctt gatccattaa ccggcttata taaccgccgt
    38881 ggcctgcaaa atcggctgga tacgttacag gcgccgggca gccatgaaca ctacgtcctg
    38941 ctattggata tcgatcattt caaagcgtat aacgatcact acggtcatat gatgggcgat
    39001 caggcgttaa tccgcgtctc agcggcaatt cgggacgccg tgcgatcgcg cgatgtcgtc
    39061 tgtcgttttg gcggggaaga atttctggtg ttgctgacca ccgccgaacc acagcaagcc
    39121 cgcgctaccg cagaacgtat ccgacaggaa gtatacgatc ttaaaatccc gcatatgttt
    39181 aacgaaagcg tcgccaccaa tgtcactgtc agtatcggca ttgcgccctt gacggatcgc
    39241 aatatcggag acgctatcga aaaagcggat aaagcgctct acgaagccaa gcatcttgga
    39301 cgtaaccaca ttctggtcag cgacgacatg cgcgccctat gaatcctgtt ggcgtaatcg
    39361 tgctacgcca acagcgttaa ccataaaccg cttgccatcg tttatcgcta tcgataggat
    39421 tagcaatcat tatcatttag attaacatca ttaaactgcg ctatggccta ccgttccgca
    39481 ccgattgctg acgatattat ctggcgagct gctccccagc cggaagacgc ctcgctggcg
    39541 gacgcagtac gcgagacgat cgcctctacc cgtcagcacc tgttggactt catccggctg
    39601 gatgaaacgc cgccgccaac ggcgatgact cttgcccagt ggacgcgccc cgcgacgttt
    39661 cgttcattgc tggccgccta ttccgatcac atctatcggc acacgccagg cctgccacgt
    39721 gaaaataagc cgttactctc cctgtgggcg caatggtata tcgggctgat gacgccgccg
    39781 ctgatgctgg cattactgac gcaagcgcgc gctatcaatg tctcggcaga acatattcac
    39841 gttgaatttc atgaaaccgg gcgcgccgcg tgtttctggc ttgatgtgca tcaggataac
    39901 ctggcaacgg aacgttcccc ggaagaacga atggaaacgc taatagtctc cgcactacag
    39961 ccggtcattc aggcgctgga ggcgactggc gacatcaacg cgaaacttat ctggagcaat
    40021 accggttatt taatcaactg gtatctgact gagatgaaac cgctgcttgg cgaagccctg
    40081 ctggcaacgc tacgccagcg ctgttttttt gaaaagcagc tatccgacgg tcaggataac
    40141 ccgctgtggc ggaccgtcgt aatgcgcgac ggtcttctgg tacgcagaac ctgctgccaa
    40201 cgttaccgct tacctgacgt acagcagtgc ggcgactgca cgctaaagta aaccgcttta
    40261 cgttgccttc agttatcgtc acggcttact gctgctggcc tgtcacatta ttatatttac
    40321 agcggcgctc tccgtatgcc aaattacgtt ttgccatttt tgggtctacc gtggctattg
    40381 gtaaggtctc aggagagaag aatgagtctg caatctgtac ggcaatttct ggccgctcat
    40441 gctcccgata ttgaaattat cgaattaaat caaagtacag cgactgtcga actggcagcc
    40501 aaagcgcaca acgtagagcc agggcagata gctaagacgc tctcgcttaa agtaaaagac
    40561 accattatcc tggtggtcgc gaaaggcgat gcccgcctgg ataataagaa gcttaaaacc
    40621 actttcggcg caaaagcccg tatgttgagc agcgatgaag tggtcaatgc aaccggacat
    40681 cctgtcggcg gcgtatgtcc tttcgggctg gagcacccgc tgcccgttta ttgcgacatc
    40741 tctctgaagg ggtataacga agtattgcct gccgcaggcg ccacgcacag cgcggtacgc
    40801 atcacgccgg aaagaatggc tgaactgaca tcggcgacct gggtagacgt gtgccaataa
    40861 cgtgcctgac acccggattc cccgaacaag cacggcgcat ccggcgcggg ctatacccga
    40921 tgctggagcg cggtagcatc tccggcgcgc agatataaca gaatatccgc cgcatcgagt
    40981 aacccggcat cagaactcac gcccagcttg gacatcacat taaacttatg cgcccggata
    41041 gtcttaatgt tacgttctaa ctggacggca atttgcggca ttgagtagcc gttcgacatg
    41101 aaacgcagaa tctcccgctc ggttggacta agcatacaat tctggtgaag ttcccaaaga
    41161 ttgtctgtac gctccgttgt ccgccgggcg ctattaagcg atgtaaataa ggcatcctgt
    41221 aaaacatcca acggcgacgc tttgctgatg accccatcca gcggcagcgg ggataatgcg
    41281 ctgattaagc gggcttcagc atcatcatcg gcaatcacca gacgccgcat atggggataa
    41341 tttatcgcca gttccgtcag gctggataat cctgtccggc gttcagttct taacgcagaa
    41401 agagaaaaaa taacggcaga aaacggcgtc tttagcgcag ccttataaaa cgcggatggt
    41461 tttgaaaaaa tatgaagcgt atgtcggcaa tccggcattg catcaaatag ccctttaata
    41521 ccaatggtgc tcatcacgca tttttctacg agcgcaacat ttctcttgct gattctgttt
    41581 tccattccat ggtttctcca tataccgaag gtaggttcaa ttctctggct ccctgagaac
    41641 tgtttatcca tgcatacatc tctgcattac tgtgtattga taagcgtcgc atggcgctat
    41701 ttttttgggc gctaattgtt ttattacttt ttttaagtaa cgccgcaatt tggttaatgc
    41761 cccacccttt tcctaaaagg cgtaatactt ttcgttcaga cagcgtaagg acaatcggcc
    41821 tgtcgtggga ctgctgaatt tcagacggta cctgaggcga taataacgtt ttacttattc
    41881 tttctgagcg agcgtttccc gcatggataa cgctaataag attctcgatt ggctcttcgt
    41941 ctgaaagcaa ggtgctgacg gggcccatca ggagatcaac cgcatgtgga tagcaggatt
    42001 taggaaccag aaatacccaa tgtatgtcgc gatattgcga gattaagcta taaaaatatt
    42061 cgcagatagc gcggggagag gcattgttaa ctgctaaatc agcaataact aaattacttc
    42121 ggcgtagctg tagcagcgtt agctcttcta tcgtacgaca atacgccagt ttataatcgg
    42181 ggaaattacc tgttatagcc cctttaaggc cttcctgtat aagaggggtt ttactgataa
    42241 taagtccatt tttgcagcat cctggcagca taattcctcc gcacccacgc cgccactttt
    42301 cattgcccca ttaataaaaa cactattaac aatgatcgca aagaaatata ggccgagtgg
    42361 attaattatc cttgttttat ttttaaatat ctaacattga ttgcgctaca atccacatag
    42421 cacaaaaaca tgaaatcact atcgcatagt tactcataaa accagaagca agacaattaa
    42481 attaactaaa tttgcacatt agcaattcta acgaaaacgc atcatattaa taaatttaaa
    42541 atatgagttc gcccttcatt catattgctg agtcctaaaa caaaagccca acaatactgt
    42601 ccaccatcca taaaacccat gtaatatcta cgaattacac taagtcatgc ctatttttac
    42661 acccgctgct cacgccattg tggttaaacc attaatgcat atagttgata aaattcacca
    42721 catcattgat tcaaaaatga gcggccagac tggcataatg cctctattct ggaaacggac
    42781 atacgagaac cgtcgcccat aaggatatcc tgcctgtgac gaagcgcacg tctcaggaag
    42841 cttatgcgtt gcgtctggtg gttgacgttt ttatcaacaa gaaattgatc ttaaccaacg
    42901 ccatcatgcc tgcgcttcgt gttaaaaaga aagcctctgt catagtggcg gcgcatagaa
    42961 tgtcttttcg gacaggacga gtcatgcaag aagagcaatc aattcaacga gcagtaacac
    43021 ggttatgtat tcaatgcggg ctgcttttat tgcagcacgg ggcggaaagc gcactggttg
    43081 atgagctttc cacccgcctc ggtttggcgc tcggtataga tagcgtcgaa agcgcgatct
    43141 cctctaacgc cattgtcctg acgaccatta aagacggaca atgtctgaca tcgacacgta
    43201 aaaaccagga tcgcggcatt aatatgcacg tcgtcacgga ggttcagcat atcgttatcc
    43261 tcgcggaaca tcgtctgctg gattacaaag gcgtggaaaa acgctttagc cagctccgcc
    43321 cgctgcgtta tccgcgctgg ctggtggcgt ttatggtcgg tctttcctgc tcctgctttt
    43381 gtaagctgaa taatggcggc tgggatggcg cggttatcac ctttttcgcc agtatgatag
    43441 ccatgtatat ccgccagatg ctggcgcagc ggcatttaca tccgcagatc aatttttgca
    43501 ttaccgcctt tgtcgctacc acgatttccg ggctgatgct cacccttccc gcctttagcc
    43561 agacgcccac tatcgccatg gcggcgagcg tactgctact ggtgccgggc tttccgctga
    43621 ttaattccgt cgcagatatg tttaaaggac atattaatac cgggctggcg cgctgggcta
    43681 tcgccagcct gttgacactg gccacctgtg tgggcgtagt gatgtcaatg acaatatggg
    43741 ggctacgagg atgggtataa tcgacttttt actggcgcta atgcaggaca tgatcttgtc
    43801 tgcgatcccc gccgtcgggt ttgcgatggt ctttaatgtt ccccaccggg cgcttccgtg
    43861 gtgcgcgcta ctgggggcgc tgggtcatgg cttgcgtatg ctgatgatga gcgcaggctt
    43921 taatatcgaa tggtcgacgt ttatggcttc gctgctggtc ggcagtattg gtattcagtg
    43981 gtcacgctgg tatctcgctc accctaaagt gtttaccgtc gcggccgtga tcccgatgtt
    44041 tccggggatt tccgcctata ccgcgatgat ttccgcagta aaaattagcc atctgggcta
    44101 tagcgaaccg atgatgatta cgctgctgac caattttctg aaagcctctt ccattgttgg
    44161 cgcgctctca attggcctct ctgtaccggg attatggctg taccgcaaac gcccccgcgt
    44221 gtgatcggtg gaacgcctcc tgctgttctt acaggtctgt gtggtactat aaaaacagtc
    44281 gcccttctcg gttgttgttc catattgaga aacattatgt cttccagaat tttaacgtcg
    44341 gacgtcatcg gtattgacgt ccttttacac gatcatcatg ctgtgctggc gaagtcaacg
    44401 ggcggcgcag tggcggtatt cgctaataat gcgcctgcct tttatgccgt gacgcctgca
    44461 cgcatggctg aactgctggc gcttgaagaa aagttatcac gtccgggaag cgatgtggcg
    44521 ttagacgcgc aattttacga agaacccgaa gccgcccccg ttgcgattcc ctgcggaaaa
    44581 ttcgccatgt atcccgcctg gcaaccggat gcggattttc agcgtcaggc tgccctttgg
    44641 ggcgtggcgc ttcgggagcc tgtcaccgca gaagagctag cggcgtttat cgcctactgg
    44701 caggcggaag gtaaggtttt tcaccatatc cagtggcagc aaaagctggc gcgcagcgtg
    44761 caaatcagcc gttccagcaa tggcggaatg ccgcagcgcg acatcaatag cgtcagcgaa
    44821 cctgacaatc atattccacc aggttttagg gggtaacgat gaaaaatgtt ggcgacctga
    44881 tgcagcgtct acaaaaaatg atgcctgcgc atattacgcc ggcgtttaaa acgggcgaag
    44941 aactgctggc ctggcagaaa gagcagggcg agatccgggc ggcagcgctg gcgcgggaaa
    45001 atcgggcgat gaaaatgcag cgcaccttta accgttccgg cattcgaccg ctgcatcaaa
    45061 actgctcgtt tgataactat cgggttgagt gcgacggaca aatgaacgcg ttaagcaaag
    45121 cccgacagta cgtggatgaa tttgacggca atatcgccag ctttgtcttt tccggcaagc
    45181 cgggaaccgg taaaaaccat ctcgccgcgg ctatttgtaa cgagctgctg ctgcgcggaa
    45241 agtcggtact gattatcacc gtagcggata ttatgtcagc gatgaaagac acgttcagca
    45301 atcgggaaac cagcgaagag cagttgctta acgatctgag taacgttgat ctgctggtga
    45361 tcgacgagat cggcgtgcag accgaatccc gctatgaaaa agtgatcatc aatcaaattg
    45421 tcgatcgtcg ttcctcgtca aaacgtccca ccggcatgtt gacgaacagc aatatggaag
    45481 agatgacgaa aatgcttggc gaacgcgtca tggaccgtat gcgtctcggc aacagtttat
    45541 gggttaattt tagctgggac agttaccgca gccgagtgac gggtaaagag tattaaattg
    45601 caacgtgcgc cagggcgata cgacgcctag ctggcataac acaggtgatt accatgaata
    45661 cagcgaaaca tgttctgtgc tgcgcggcga tcgccagcgt actgatttcc accagcggta
    45721 ttgccgccag tcagttaagc gctcagggcg cgaacgcaca gcagggcggg atgtcgcttt
    45781 ctgcgctaac cggtctgctc agcagaggtg cccagtcgct cagtgctgat aatatgaata
    45841 atgccgccgg tattttgcag tactgcgcca aacagaaact ggcgtccgct accaacgtgg
    45901 aaaacgttaa aaatcagatt ctgaacaagt tagggttgga taccacacag caggagcagg
    45961 acactaacta cctgaacggc ctgcaagggt tgctcaagac gaaggacggc cagcaattga
    46021 acctcaataa tatcggcagt acgccgctgg cggaaaaggt gaaaaccaaa gcttgcgatc
    46081 tggtgttgca gcaagggctg aatttcctct cctgactgcg cttttctgac cgtgcgccac
    46141 gccgggacgc cctgttaaaa gccgtgtttt ggccctttac ccgccaacac ggcattaacc
    46201 cgacttttct cttcgtcttt tcctgttatt aaccgctatg gcaggaagtg atgccgatca
    46261 aaaaaccaac tttctaaact cattctaaat aacagcgccg tgtaaagtta ttagaattgc
    46321 agcaatgtga catcgctatt acattgttag aaattttttc ctgccagcga taagcctggt
    46381 ttattgagga tcgtcagttg tccgagttgc tctctgtcgc tctgtttctc gcctctgtgc
    46441 tgatatatgc ctggaaggcg ggccgtaaca cttggtggtt tgccgccact ctcacggtgc
    46501 tgggactttt tgtcattctg aatattaccc tgtatgccag cgactatttt accggcgacg
    46561 ggatcaacga cgcagtgctt tatacgctca cgaatagtct gacgggagcg ggagtcggca
    46621 aatatattct gccgggaatc ggcattgccc tggcgttagt ggcggtattc ggcgcgctgg
    46681 gatgggtact acgccgccgc cgtcaccatc ctcatcatgt cggttacagc ctgctggcgt
    46741 tactgctggc gttgggttcg gtcgacgcca gcccggcgtt tcgccagatt accgaactgg
    46801 taaaatcaca aatgcgcgat ggcgatccgg attttgccgt ttattataaa gaaccagcaa
    46861 aaaccattcc tcatccgaag ctcaatctgg tctatatcta cggcgagagc ctggaacgga
    46921 cctattttga taatgacgcg ttccccaatc tcacgccaga gttgggcgcg ctgaaaaatg
    46981 aggggctgga tttcagccat accatgcaac tgccgggaac ggattacacc atcgccggga
    47041 tggtggcttc ccagtgtggt attccgctgt ttgcgccgtt tgagggcaat gcgtccgcgt
    47101 cggtttccag cttcttcccg cagaatatct gcctcggcga tattctgaaa aactccggct
    47161 accagaacta tttcgtgcag ggcgctaacc tgcgttttgc cgggaaagac gtgttcctga
    47221 aatcacacgg atttgatcat ctgtacggcg ctgaagagct aaaaacggtg gtggcggacc
    47281 cgtcttatcg taacgactgg ggcttctacg acgatacggt gcttgatgag gcatggaaga
    47341 aatttgaagc gctttcccgc tcaggccagc gtttttcgct gtttacgctg accgtagata
    47401 ctcaccaccc ggacgggttt atctcacgca cctgcaaccg taaacgctac gattacgacg
    47461 gcaagcccaa ccagtccttt agcaccgtaa gttgcagcca ggaaaacatc gccgagttta
    47521 tcaacaaaat caaagcgtca ccgtggttta aagataccgt tatcgtcgtc tcttccgacc
    47581 atctggcgat gaacaatacg gcctggaaat acctgaataa gcaagatcgc aacaatctgt
    47641 ttttcattct gcgcggcgat aaaccgcagc aggagacgct ggcggtcaaa cgcaacacga
    47701 tggacaacgg cgcaacggtg ctggatattc tcggcggcga taattttatc ggtctgggac
    47761 gtagcagcct ttccgggcag tcgctgtcgg aagtgttcct gaatgtaaaa gagaaagtgc
    47821 tggcgatgaa gccggatatc attcgcctgt ggaatttccc gaaagagata aaagatttta
    47881 ccgtcgatcg ggacaaaaac atgatcgcgt tttccgggag ccacttccgc ctgccgttac
    47941 tactgcgcgt atcggataag cgcgtcgagc cgttaccgga aagtgaatac tccgctccgc
    48001 tacggttcca gttggccgac ttcgccccgc gcgataattt cgtttggatc gatcgctgct
    48061 acaaaatggc gcagctatgg gcgccggcgc tggcgctctc taccgactgg tgcgtctcgc
    48121 agggacagct tggcgggcag caaaccgtac agcatgttga taaagcgcag tggcagggta
    48181 agacggcgtt taaagacacg atgatcgata tggagcgcta caaaggcaac gtcgatacct
    48241 taaagattgt cgataacgat attcgttata aagccgatag ctttattttt aatgtggcgg
    48301 gcgcgccgga ggaggtgaag cagtttagcg gcatttcccg gccggagtcc tgggggcgct
    48361 ggtcaaatgc gcagttgggc gatgaggtta aaatcgaata taaagcgccg ctgccgaaaa
    48421 agtttgatct ggtgatcacc gccaaagcct tcggcgacaa cgcgaatcgg ccgattccgg
    48481 tacgcgtagg caacgaagaa cagacgctgg tgctgggtca cgatgtgtcc actatcacgc
    48541 tgcatttcaa caacccgacg gacgcgaata ccttagtcat tgcgccgccc gctcccgtct
    48601 ccaccaacga aggtaatatt ttgggccatt cgccgcgcaa attggggatt ggcatggtgg
    48661 agatcaaagt ggtgaatgtt gagagttaaa agagaatgtc atatatgccg ggtgcggcta
    48721 cgccttaccc ggcctacaca tcatctttat caataaactg gcgcataggc ctggtaagcg
    48781 ctacgccatc aggcaaaagt gtgaacatct catccggcct acggtcgtct gtaggccgac
    48841 tgttcaccac tacgccctta aaacgtttcc caattatcgc tgccgtcggc cacagcggcc
    48901 tttggtgacg acacggctgc cggggttttt accgctgcca cttcacgcgc acgctgctgt
    48961 tgctggtgaa tacggaacac cgcgacggcc tgggtcagac ggctggcttg ctcttccagc
    49021 gccgcagccg cggcggcgga ctcttccacc agcgaggcgt tctgctgcgt tacgcgatcc
    49081 atctccgcta ccgccaggcc cacctggtcg ataccacggc tttgctcgtc agacgccgag
    49141 gcaatctcgc ccataatgtc ggtcacgcgg gtaactgcat tgacgatctc atccatggtt
    49201 tcaccggcgc tttcgaccag cgtcgaccct acatcaacac ggctcacgga atcctcaatc
    49261 agactcttga tctcccgtgc cgcctgcgcg ctacgctggg ccagattacg gacttcaccg
    49321 gccaccaccg cgaacccgcg tccctgctcg cctgcgcgcg ccgcttctac cgccgcattc
    49381 agcgccagaa tattggtctg gaaagcaata ccgtcgatta cgctgataat atcggcgatt
    49441 ttctgcgaac tggaggcgat atcgcgcatt gtttgtacga cgttatccac tactttgccg
    49501 cctttttgcg ctgtctctga cgcactcagc gccagatggc tggcctgacg ggcgttttcg
    49561 gcgttctgtt tcacggtggc ggtcagttgt tccatactgg cggcggtctc ttccagagac
    49621 gctgcctgct gctcagtacg ggaagagaga tcgttgttgc ccatcgcaat ctcgctggcg
    49681 ccgctataga ttgcattcgc gccgttacgt acatcgccaa cggtacgcat cagttcactt
    49741 tgcatatgac gcaggttttc agccaactgc cccatttcgt tggagccttc cacgtcgata
    49801 cgcttcacca gatcgccgct ggcgatatga cgaatgcttt caatcagacg attcatcggg
    49861 gcgataagcg acagtttgat gccgaaccag acggcgataa tgaccaccag aacggcaatc
    49921 agcacactga ccagtaccca catcgcctgg ttgtaggaac tgttgttatc ctcaacagca
    49981 atatcgtaca gacgatcgtt ttgctgcata taggccatgt actgcttctc aaaagcgtcc
    50041 tgatagcttt gagtcggttg atcaaaaact cgttaatctt acccgcgcca agaagctgaa
    50101 taagctccgc caacgcgtcg tggtagatat cataggttcg tttgatctca aggaaagccg
    50161 cctcactctg acgtggatcg cgcggtaacg cctcatactg cgcccagttt ttttcggtca
    50221 gcttcagcgt attggtcgcc ccctgcatca gttcagcgac agttgcgccg ctgccaatat
    50281 tgctctggtc catcatccag cggatacccg cgcgattcag ggtattacgc gtttgcaaca
    50341 gttccaccca gattgcattc agggcagact gctgctgacg aatggtttgc aatacggtga
    50401 agttttcttt gtcattcttc agcgagttga agaacagccc gccggatgtc agttgtaaaa
    50461 ggccaaatag cgccaatacc agcagtaagc tggtaacaat tttaattcgc tttaacatgt
    50521 tttctctttc cgctagacag atacagaatt ttcggcctgg aaagggaaaa ctttatggga
    50581 tgcgcgccat taatatcacg attagctcag tgaagtcgtt atgacgcccc gcgcaacaag
    50641 gatcgtccca ttttatatcg tgatctcaat cacataaaat agcccacgcc ctcctccgcg
    50701 aaaccgctta ccggtacgtc cgaccgctta aaccgccata caaccactca ctgatttacc
    50761 taactttacg cgcgcgatga tctggcaaga tcctctcagc atagcagtca atctacctcc
    50821 tcaaacacga actcaatgtc cacccagctt cggctgataa ttaaacttac aaccaggttt
    50881 tactatggat acgaaaaaga tattcaagca cataccctgg gtgattctcg gaatcatcgg
    50941 tgctttctgc ctctcggtcg ttgccctacg tcggggtgaa cacgtgagcg ccctgtggat
    51001 cgtggtcgct tccgtttccg tctatctggt ggcttaccgc tactacagcc tgtacatcgc
    51061 ccagaaggtc atgaaactcg acccgacgcg cgcgacgccg gcggttatca ataacgacgg
    51121 cctgaactac gtgccgacta accgctacgt gctgtttggt caccacttcg ccgccatcgc
    51181 cggcgcaggt ccgctggtcg ggccggtatt ggccgcgcag atgggctatc tgccggggac
    51241 actgtggctg ctggcgggcg tagtgctcgc gggcgcagtg caggacttta tggtgctgtt
    51301 catctcttcc cgccgtaacg gcgcctctct tggcgagatg atcaaagaag agatggggac
    51361 cgttccaggc accatcgcgc tattcggctg cttcttaatc atgatcatca tcctcgcggt
    51421 gctggcatta attgtggtta aagcgctggc cgaaagcccg tggggcgtct tcactgtctg
    51481 ctcaacggtg ccgattgcgc tgtttatggg catctacatg cgcttcctgc gtccgggacg
    51541 cgtaggcgaa gtctccgtta ttggtatcgt gctgctggtg gcgtctattt acttcggcgg
    51601 cgtaattgcc cacgacccgt actggggccc ggcgctgacc tttaaagaca ccaccattac
    51661 cttcgcgctg atcggctacg cctttgtttc cgcgctgctg ccggtatggc tgatcctcgc
    51721 cccgcgcgac tatctcgcta ccttcctgaa aatcggcgtg atcgtcggtc tggcgctggg
    51781 gattgtgatc ctcaacccgg aactgaaaat gccagcattg acgcagtatg tcgacggtac
    51841 cggcccgctg tggaaaggcg ctctgttccc gttcctgttc atcaccatcg cctgtggcgc
    51901 cgtctctggc ttccacgcgc tcatctcttc cggcaccaca ccgaaactgc tggcctgtga
    51961 gaccgatgcg cgttttatcg gctacggcgc gatgctgatg gagtcctttg ttgcggtgat
    52021 ggcgctggtg gcggcctcga tcattgaacc gggtctctac ttcgcgatga acaccccgcc
    52081 ggcaggtctg ggcattacca tgccaaacct gcacgagatg ggcggcgaga acgcgccgct
    52141 gattatggcg cagttgaaag acgttactgc acatgcagcg gcgaccgtca gctcctgggg
    52201 ctttgtgatt tccccggaac aaatcctgca aactgcgaaa gatatcggtg aaccgtcagt
    52261 attgaaccgc gcaggcggcg cgccaacgct ggcagtaggt atcgcgcacg tgttccacaa
    52321 agtcctgccg atggcggata tgggcttctg gtatcacttc ggtattctgt tcgaagcact
    52381 gtttatcctg accgcactgg atgcgggtac ccgttccggc cgctttatgt tgcaggattt
    52441 gctgggtaac ttcgtcccgt tcctgaaaaa aaccgattct ctggtcgcgg gtatcatcgg
    52501 taccgcaggc tgcgtcggtt tgtggggcta tctgctgtat cagggtgtgg tcgacccgct
    52561 gggcggcgtg aagagcctgt ggccgctctt cggtatctct aaccagatgc tggccgccgt
    52621 ggcgctggtg ttgagcaccg tggtactgat caaaatgcag cgcaccaagt acatctgggt
    52681 gacggtaatc ccggcggtat ggctgctgat ctgcaccacc tgggcactgg gcctgaaact
    52741 gttcagcgcc aacccacaga tggaaggttt cttctacatg gcaaacctgt ataaagagaa
    52801 gattgccaac ggcaccaacc tgaccgcgca gcagattgcc aatatgaacc atatcgtggt
    52861 gaacaactac actaacgctg gtttgagtat tctgttcctg gtggtggtgt acagtattat
    52921 cttctacggt ttcaccacct ggatgaaggt acgcaacagc gataaacgta ccgataaaga
    52981 aaccccgtat gtgcccgtgc cggaaggcgg cgtgaagatc tcttcacacc actaaaactg
    53041 atgccgggta gcgcacagcg atcccggcta gtgtaggccg gataaggcgc aagccgccat
    53101 ccggctttat tcattaacag gacggcagaa tgtttgatac tttaggtcag gcaaaaaaat
    53161 atctcggcca ggcggcaaaa atgttgattg gtattccgga ctacgacaac tatgtcgagc
    53221 acatgaaaac caaccatccc gacaagccgt acatgaccta tgaagagttc ttccgcgaac
    53281 gtcagcaagc acgttacggc ggcgatggca aaggcggtat gcgctgttgt taatggagag
    53341 actatgaccc cgattgcagt taccctactt accggttttc ttggtgccgg caaaaccacc
    53401 ctactacgcc atatcctcaa cgaacaacat ggttttaaaa tcgccgttat cgaaaacgaa
    53461 tttggcgaag tctccgttga cgatcaactg attggcgatc gcgccacaca gatcaaaacc
    53521 ctgactaacg gctgcatctg ctgtacccgc tccaacgagc tggaagatgc gctattagac
    53581 ctgctcgaca gccgcgaccg cggcgatatt gctttcgacc gcctggtgat tgaatgcacc
    53641 ggcatggccg accccggccc gattattcag acctttttct accatgacgt attatgcgaa
    53701 cgctacctgt tagacggcgt gattgcgctg gtcgacgcgg tgcacgctaa cgagcagatg
    53761 aaccagttca ccatcgccca gtcgcagata ggctacgccg accgtatcct gctgaccaaa
    53821 accgacgtgg caggcgacag cgagaaactg cgcgagcggc tggcgcgtat caacgcccgc
    53881 gccccggttt acaccgtggt acacggcgat attgacctga gtcagttgtt taataccagc
    53941 ggctttatgc tggaagagaa cgtgctggca agccaaccgc gtttccactt tattgccgat
    54001 aaacagaacg atgtgtcgtc aattgtggtg gaactggatt acccggtgga tatcagcgag
    54061 gtttcgcggg tgatggaaaa cctgctgctg gaatcagcgg ataaactgct gcgttacaaa
    54121 gggatgctgt ggatcgacgg cgaacccaac cgcctgctgt tccagggcgt gcagcgtctc
    54181 tacagcgccg actgggacag accgtggggc gacgaaacgc cgcatagcac gctagtgttt
    54241 atcgggatcc agttgccgga agacgagatc agagcggcgt ttgcggggtt aaggaagtaa
    54301 ccattaagcg cttatctggc ctggcgggaa tttgtaggcc ggataaggcg cagccgccat
    54361 ccggcatctt ctggctattt cttattttgc tcgcgcagca tcgcttcgcg cagaatggca
    54421 ttcagccgcg tctggtagcc ttttcctggc cgtttcagcc attccataac gtcggcgtca
    54481 atacgcaccg aggcctgagt ttttaacggg cgaaaaaact taccacgcac tgcttcagac
    54541 cactgtccat cctccgaagc gggaatgtcg ctgtaatcaa tctcatcatc tgattttttc
    54601 gccagcgcct tcagttcagc ctcatgctga gcactcagcg cggatgcgtt gccgcgttta
    54661 tgtttaacca tgctcataac gattcctctc ttttctgtct gccttacgag cgctgatgat
    54721 acggataact tcaaaaccac tttcgaaccg aacgctatga gcaaccagaa tgaccacaat
    54781 gccatgaaca aggccgaggg tctgccaacg atattctcca ttctcataac gctcctgacg
    54841 tgacaggtgt cggggatcgt caaacaccag taccgcatcc tcaaagcgga caccgtgctt
    54901 cctcaggttg cttttagcct tgttcgcatc ccattcaaac tccatcggca tgtgttttcc
    54961 ctaattgtat atacaaaaat gtatatacaa ttatcttacg attatacctg gattgttgga
    55021 aatagcttca caatttgcgt attcgagata aaagaaaatt gaccagaaga gtaggccgca
    55081 gaaggcatgg gtttaggctg atacgcagcc atagaaagtc acgtgatttc tgggcgagag
    55141 gaaacacagg tgcccacaac gtggtccatc tcaattaccc gtaatcaggt tccagcgtta
    55201 ccactactca aagtaatcca tatcgagctt tggcaacttg agtaaacgtg aggatacgcc
    55261 aatatcatta tcaatcatca gatgcaccag cctgtcgcca tccaccagca ccagaccttc
    55321 aactttgtta gcatagtctc tggcatgcgc cgtaaagcct gaggtggtaa taaagacgcc
    55381 acgtttcact ttttgctcag gcaatgcacc ataaaagccc ctgacttcag cgctcccgac
    55441 ggtgcctttc cagcgtttgg cctgaacgta gactttttcc agcccgagct tatcgagaga
    55501 gataataccg tcaatgccgc catcgccggt tcccccgacg cgctgcaaat caccgcgatg
    55561 accgccatat cccaggcggt gcaacacatc taacacaatc acttcaaaac gcgccggcga
    55621 aacctgaagc aggttctcca gcaattcttc ggcaacagat tcacgaatct cattgagcgc
    55681 ttgctccagg cgatcgtccg ggctgcttct ggcaagctca tcatcctcaa tcgattctgg
    55741 ctgtggatct aacgccaccg catctgccgg cttactgagc tttacgccgt taaaatcaca
    55801 agcaaaatga ctcacttcct gctcggtcat cggctgcgga tgcgaggcaa cccagctcat
    55861 tcccgctggt gttaaacacc attttccccg ggataggctc tgcgataacc cggcgcgttt
    55921 gagacgatcg tgcgcccaac cggtgcggtt ctggtacgtc agttgtccac tggtaatcac
    55981 ctctgcacgc tgctgctcat ttaacccaag catttcggct gcagcttcac gcacttctct
    56041 gaccaaagcg ccctcgggtc gagtggccag aaaacgcaac actggttcaa taaatttgtc
    56101 atatgttgga acagccataa atccatccct gctattgata tagattagat accccgccgg
    56161 agaacgatac tcttcaggaa aacattagga aagaagcagt tactctctga ttgttcgttg
    56221 atcacacaca atatgaagtc taccatgggt ctgttatttt ccctttacgg cacaaggtaa
    56281 taacgtcttc ccgctcagga accggataga taaaaatgaa caaatctaac ttcgactttc
    56341 tcaaaggcgt caacgacttc atttacgcca tcgcctgcgc ggcggaaaac aactatccgg
    56401 acgatcctaa taccactctg ataaaaatgc gcatgtttgg cgaagccacc gcgaaacatc
    56461 tcggccagtt gctggatata cccgtctgcg aaaaccaaca tgacctgcta cgcgaactgg
    56521 gcaagattgc gtttattgat gacagcatcc tttctgtttt ccataagctg cgccgtatcg
    56581 gtaacctggc cgtccacgaa tttcataacg atctggacga tgcccagatg tgcctgcggc
    56641 tcgggttccg cctcagcgtc tggtactacc gactggtaac caaagattac gatttcccgg
    56701 tgccgatgtt tgttctgcca gaacacggcg agaatcttta tcaccaggaa gtgctgacgc
    56761 tgaaacaaca gttggaacgt caggcgcaag agaaagtaca aagtcaggcc gaactggaag
    56821 ctcagcagca aagactggtt gcgctcaacg gctacattgc catccttgag ggcaaacagc
    56881 aggaaaccga agcccagacc aaagcacgtc tggccgcgct ggaggcacag cttgcggcaa
    56941 aagatgccga actggcgaag caaaccgaac aggaacgtaa ggcctatcac aaagagatca
    57001 ccgatcaggc tatcaagcgc acgctgaatc tcagcgaaga agagagccgc ttcctgatcg
    57061 acgcccagtt gcgcaaagcg ggctggcagg ccgacagtaa aacgctgcgc tttgccaaag
    57121 gcgctcgccc ggaacccggc gtcaataaag cgattgccga atggccaacg ggtacagatg
    57181 aaacgggaaa aacaggcttt gccgattacg tattgttcgt tggcctgaag cccatcgccg
    57241 tcgttgaagc gaaacgcaaa aataccgatg tcttcagcaa gctcaacgag tcttaccgct
    57301 acagtaaata cttcgataac ggatttttac gcgacacgct gctggagcac tacgctcccg
    57361 acgaagtgca tgacgccgtg ccagagtatg aaatcagctg gcaggacacc agcggcaaac
    57421 agcgctttaa aatccccttc tgctactcca ccaacgggcg cgaataccgc gcagcgatga
    57481 agaccaaaag cggtatctgg tatcgcgatg tccgacacac caccaatatg tcaaaagcgc
    57541 tgccggaatg gcatcgcccg gaagagctgc tggatatgct gggcagcgac ccgcagaaac
    57601 aaaaccagtg gtttgctgaa aaccccggaa tgagcgaact cggcctgcgc tattaccagg
    57661 aggatgccgt ccgcgcggtg gaaaaggcta tcgttaacgg ccagcaagag atcctgctgg
    57721 cgatggcgac cggtaccggt aaaacccgta ccgccatcgc cctgatgttc cgcctgatcc
    57781 agtcgcagcg tttcaaacgc gttcttttcc tggtcgaccg tcgctcgctt ggcgaacagg
    57841 cgctggggtc gtttgaagac acgcgcatta acggcgacac ctttaacagc atttttgata
    57901 tcaaagggtt gaccgacaaa ttcccggaag acagcaccaa aattcacgtc gccacggtgc
    57961 agtcactggt caagcgtacg ctgcaatccg atgagccaat gccggttggc cgctacgact
    58021 gtatcgtcgt cgatgaagca caccgcggct acattctcga taaagagcaa accgagggcg
    58081 agctgcagtt ccgcagccag ctggattacg tttccgccta ccgtcgcatt ctcgaccatt
    58141 tcgatgcggt aaaaatcgcc ctgaccgcca cgccagcgct gcatacagtg gagattttcg
    58201 gcgaaccggt ttaccgctac acctaccgta cggcggtgat cgacggttac ctgatcgatc
    58261 aggatccccc tattcagatc gtcacccgca acgcgcagga tggggtctat ctttccgagg
    58321 gtgaacaggt ggagcgcctg aacccacagg gcgagctgat caacgacacg ctggccgacg
    58381 atcaggattt tgaggtcgcc gactttaacc gtggcctggt gatcccggcg tttaaccgcg
    58441 cggtatgcgg cgagctcacc aaatacctgg atcccatcgg gcaacaaaaa acgctggtgt
    58501 tctgcgtcac caacgcccat gccgacatgg tggttgacga actgcgtacc gcgtttaaga
    58561 aaaagtatcc gcagcttgag cacgacgcga tcatcaagat caccggtgat gccgataaag
    58621 acgcgaagaa agtgcaaagc atgatcgtcc gtttcaacaa agagcggttg cccaatatcg
    58681 tggtcaccgt cgatctgctg accaccggtg tggatattcc gtctatctgt aatattgtgt
    58741 tcctgcgcaa agtcaaaagc cgcattctct acgagcagat gaagggccgt gccacgcgtt
    58801 tgtgcccgtc ggtagggaaa accagcttta agatttacga ctgcgtggat atctacagtt
    58861 cgctggaaag cgtcgacacc atgcgcccgg tggttgtgcg tccgcaggtg gagctgcaaa
    58921 cgctggtcaa cgaaattacc gactcagaaa cctacaaaac cattgaagcg gatggccgca
    58981 gttttgccga acacagccat gaacagctgg tcgctaagct gcagcggatt atcggtcttg
    59041 ccacctataa ccgtgaccac agcgaaacgg tggataagca agtacgtcgt ctggacgaac
    59101 tgtgcctgga tgccgcgggc gttaactttg gtggtctggc ttcgcgcctg cgggaaaaag
    59161 ggccgcactg gagcgccgag attttcaata agcttcctgg ttttatcgcc cgcctcgaaa
    59221 ggctgaaaac cgatatcaac gccctgcgcg atgcgccgat cttcctcgat attgacgatg
    59281 aggtggtgag cgtcaaatcg ctgtacggcg actacgatac gccgcaggac tttctcgaag
    59341 cgttcgatgc gctggtgcaa cacgccccta acgcccagcc ggcgctgcag gcggtgatca
    59401 atcgtccgcg tgacctcacc cgtaaagggc tggtggaatt gcaggagtgg tttgaccgcc
    59461 agcattttga agagtcctct ctgcgcagcg cgtggaaaga aacacgcaat gaagatattg
    59521 ccgcccgcct gatcggccat atccgccgtg cggcggtggg cgatgcgctc aaaccgttcg
    59581 acgagcgtgt cgatcacgcg ctggcgcgta tcaaaggcga gaacgactgg agccctgagc
    59641 agctaagctg gctcgaccgt ttagcgcagg cgctgaaaga gaaagtggtg ctcgacgacg
    59701 acgtcttcaa aaccggcaat ttccaccgtc gcggcggtaa gtccatgtta cagcgcacct
    59761 ttgacgacaa cctcgacagc gtgctggata agttcagcga ttatatctgg gacgagctgg
    59821 cttaagaggg tatcatcccc gttttcgccg gatggcggcg atgccttatc cggcctacac
    59881 gtaaccctgt aggcctgata agcgaagcgc catcaggcat ctgaaatgct caatcacttt
    59941 tgcgacccac aatggtggtc gccatgtcaa atgggatctt caatgaacaa taacgatctg
    60001 gtcgccaagc tgtggaaact gtgcgacaac ctgcgcgacg gcggcgtctc ctatcaaaac
    60061 tacgccaatg aactcgcctc gctgctgttt ttgaaaatgt gcaaagagac cggtcaggaa
    60121 gcggactacc tgccggaagg ctaccgctgg gatgacctga aatcgcgcat tgaccaggag
    60181 cagttgcagt tttaccgtaa aatgctggtg catctggggg aagataagaa aaaactggtg
    60241 caggcggtat ttcataatgt gtgtacaacc atcactgaac ccaaacagat aacagaatta
    60301 gtcagcaaca tggattcgct ggactggtac agcggtacac gcggcaagtc ccgcgacgac
    60361 ttcggcgata tgtacgaagg gctgctgcag aagaacgcta acgaaaccaa atccggcgcg
    60421 ggccagtact tcaccccgcg tccgctgatc aaaaccatta ttcatctgct gaagccgcag
    60481 ccgcgtgagg tggtgcagga cccggctgcc gggaccgcag gttttttgat tgaagccgac
    60541 cgttacgtga agtcgcagac caacgatctg gatgaccttg atggcgacac ccaggatttc
    60601 cagatccacc gcgcgtttat cggcctcgag ctggtgcccg gcacccgtcg tctggcgctg
    60661 atgaactgtc tgctgcacga tattgaaggc aacctcgacc acggcggcgc catccgtctg
    60721 ggcaacacgc tgggcagcga cggcgagaat ttaccgcagg ccgatattgt cgccaccaac
    60781 ccgccgtttg gcagcgccgc gggcaccaac attacccgca ccttcgtgca cccgaccagc
    60841 aacaaacagc tttgctttat gcagcatatt atcgaaaccc tgcgccccgg cggccgtgcg
    60901 gcagtggtgg tgccggataa cgtactattt gatcgagttg gattggaaat tcgtcgagat
    60961 ttaatggaca aatgccatct gcacaccatc ctgcgtctgc cgaccggcat cttttacgcc
    61021 cagggcgtca aaaccaacgt gctgttcttt accaaaggta cggtagccaa tccgactcag
    61081 gataaggact gtaccgatga cgtgtgggtg tacgacctgc gcaccaatat gccgagattt
    61141 ggtaagcgta caccgtttac tgagcaatac ctgcagccgt ttgaaaccgt ctatggtgag
    61201 gatccgcacg gcttaagccc acgagccgaa ggtgagtgga gttttaacgc tgaagagacg
    61261 gaagttgctg acagcgaaga gaacaaaaac accgatcagc accaggccac cagccgctgg
    61321 cgcaagttca gccgcgagtg gatccgcacg gcaaaatccg attcgctgga tatctcctag
    61381 ctgaaggata aggacagcat cgacgccgac agcctgccgg aaccggacgt gttagccgca
    61441 gaagcgatgg gcgagctgga tgcactgatg cgagagctgg gcgcgggcga tgaggcggat
    61501 gcgcagcgcc agttgctgga agaa
//
LOCUS       DAJVBX010000005        57699 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.005, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000005 DAJVBX010000000
VERSION     DAJVBX010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 57699)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57699)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57699
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.005"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(194..270)
                     /locus_tag="OPV72_000237"
     tRNA            complement(194..270)
                     /locus_tag="OPV72_000237"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(234..236),aa:Pro,seq:tgg)
     gene            complement(313..399)
                     /locus_tag="OPV72_000238"
     tRNA            complement(313..399)
                     /locus_tag="OPV72_000238"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(363..365),aa:Leu,seq:cag)
     gene            complement(420..495)
                     /locus_tag="OPV72_000239"
     tRNA            complement(420..495)
                     /locus_tag="OPV72_000239"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(460..462),aa:His,seq:gtg)
     gene            complement(550..626)
                     /locus_tag="OPV72_000240"
     tRNA            complement(550..626)
                     /locus_tag="OPV72_000240"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(590..592),aa:Arg,seq:ccg)
     gene            complement(729..2114)
                     /locus_tag="OPV72_000241"
     CDS             complement(729..2114)
                     /locus_tag="OPV72_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCR9912652.1"
                     /translation="MAEKKPELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPS
                     VLLAYIIAGLFVFFIMRSMGEMLFLEPVTGSFAVYAHRYMSPFFGYLTAWSYWFMWMA
                     VGISEITAIGVYVQFWFPEMAQWIPALIAVGLVALANLAAVRLYGEIEFWFAMIKVTT
                     IIVMIIIGLGVIFFGFGNGGQAIGFGNLTEHGGFFAGGWKGFLTALCIVVASYQGVEL
                     IGITAGEAKNPQVTLRSAVGKVLWRILIFYVGAIFVIVTIFPWNEIGSNGSPFVLTFA
                     KIGITAAAGIINFVVLTAALSGCNSGMYSCGRMLYALAKNRQLPAAVAKVSRHGVPVA
                     GVALSILILLVGSCLNYIIPNPQRVFVYVYSASVLPGMVPWFVILISQLRFRRAHKEA
                     IADHPFRSIMFPWANYLTMAFLVCVLIGMYFNEDTRMSLFVGVIFLLAVTLVYKVFGL
                     NRHGTAHKVGE"
     gene            complement(2321..3061)
                     /gene="rffM"
                     /locus_tag="OPV72_000242"
     CDS             complement(2321..3061)
                     /gene="rffM"
                     /locus_tag="OPV72_000242"
                     /EC_number="2.4.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide
                     N-acetylmannosaminouronosyltransferase"
                     /protein_id="HCR9912653.1"
                     /translation="MTNNAAAPLYSLRGLPLIGWRDMSHALNYLFADGQLKQGTLVAI
                     NAEKLLTAEDNPEVRALIAAAEFKYADGISVVRSIRKKFPQAQVSRVAGADLWEALMA
                     RAGKEGTPVFFVGGKPEVLAQTEAKLRTQWNVNIVGSQDGYFTPEQRQALFARIHASG
                     AKIVTVAMGSPKQELLMRDCREVHPHALYMGVGGTYDVFTGHVKRAPKIWQNLGLEWL
                     YRLLSQPKRITRQMRLLRYLRWHYTGDL"
     gene            complement(3058..4416)
                     /gene="wzyE"
                     /locus_tag="OPV72_000243"
     CDS             complement(3058..4416)
                     /gene="wzyE"
                     /locus_tag="OPV72_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECA oligosaccharide polymerase"
                     /protein_id="HCR9912654.1"
                     /translation="MSLMQFSGLLVVWLLSTLFIATLTWFEFRRVRFNFNVFFSLLFL
                     LTFFFGFPLTSVLVFRFDVGVAPPEILLQALLSAACFYGVYYVTYKTRLRKRVVDVPR
                     KPLFTMNRVETHLTWVILMGIALVSVAIFFMHNGFLLFRLHSYSQIFSSEVSGVALKR
                     FFYFFIPAMLVVYFLRQDSKAWLFFLVSTVAFGLLTYMIVGGTRANIIIAFAIFLFIG
                     IIRGWISLWMLAAAGVLGIVGMFWLALKRYGLNVSGDEAFYTFLYLTRDTFSPWENLA
                     LLLQNYHNIDFQGLAPIVRDFYVFIPTWLWPGRPSIVLNSANYFTWEVLNNHSGLAIS
                     PTLIGSLVVMGGALFIPLGAIVVGLIIKWFDWLYELGNREPNRYKAAILHSFCFGAIF
                     NMIVLAREGLDSFVSRVVFFLVVFGASLLVAKLLFWLFDSAGLIHKRTTSLPQAQMDG
                     KL"
     gene            complement(4413..5492)
                     /locus_tag="OPV72_000244"
     CDS             complement(4413..5492)
                     /locus_tag="OPV72_000244"
                     /EC_number="2.4.1.325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDP-N-acetylfucosamine:lipid II
                     N-acetylfucosaminyltransferase"
                     /protein_id="HCR9912655.1"
                     /translation="MTVLIHVLGSDIPHHNHTVLRFFNDTLAATGEHAREFMVAGEDN
                     GFTESCPALSLRFYGSKKALAQAVIAKAKANRRQRFFFHGQFNISLWLALLSGGIKPA
                     QFYWHIWGADLYEVSNGLKFRLFYPLRRIAQGRVGGVFATRGDLSYFARQHPGVRGEL
                     LYFPTRMDPSLNAMAKERQRAGKLTILVGNSGDRSNQHIAALRAVYQQFGDTVNVVVP
                     MGYPANNQAYIDEVRQAGLALFSAENLQILSEKMEFDAYLALLRQCDLGYFIFARQQG
                     IGTLCLLIQADIPCVLNRDNPFWQDMAEQHLPVLFTTDDLNEQVVREAQRQLASVDKS
                     GITFFSPNYLQPWHNALRIAAGEAE"
     gene            complement(5489..6739)
                     /gene="wzxE"
                     /locus_tag="OPV72_000245"
     CDS             complement(5489..6739)
                     /gene="wzxE"
                     /locus_tag="OPV72_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid III flippase WzxE"
                     /protein_id="HCR9912656.1"
                     /translation="MSLAKASLWTAVSTLVKIGAGLLVVKLLAVSFGPSGVGQAGNFR
                     QMITVLGVLAGAGIFNGVTKLVAQHHDDPAQLRTVVGTSSAMVLGFSTLLALVFLLAA
                     APISQGLFGHTDYQGLVRLVALVQMGIAWANLLLALMKGFRDASGNALSLIVGSFLGV
                     AAWYLCYRVGGYEGALLGLALVPALVVVPAGIILIKRGTVPLRYLKPSWDNGLAGQLS
                     KFTLMALITSVTMPVAYVMMRNQLAAHYSWSDVGIWQGVSSISDAYLQFITASFSVYL
                     LPTLSRLTEKQDITREVVKALKFVLPAVAAASFTVWLLRDFAIWLLFSAKFTAMRDLF
                     AWQLVGDVLKVGAYVFGYLVIAKASLRFYILAEISQFILLTAFAHWLIPAHGALGAAQ
                     AYMATYIVYFSLCCGVFLLWRRRA"
     gene            complement(6741..7871)
                     /gene="rffA"
                     /locus_tag="OPV72_000246"
                     /gene_synonym="fcnA"
                     /gene_synonym="wecE"
     CDS             complement(6741..7871)
                     /gene="rffA"
                     /locus_tag="OPV72_000246"
                     /gene_synonym="fcnA"
                     /gene_synonym="wecE"
                     /EC_number="2.6.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-amino-4,6-dideoxygalactose transaminase"
                     /protein_id="HCR9912657.1"
                     /translation="MIPFNAPPVVGTELEYMQSAMSSGKLCGDGGFTRRCQQWLEQHF
                     GSAKVLLTPSCTASLEMAALLLDIQPGDEVIMPSFTFVSTANAFVLRGAKIVFVDIRP
                     DTMNIDETLIEAAITDKTRAIVPVHYAGVACEMDVIMALADKYNLFVVEDAAQGVMST
                     YKGRALGTIGHIGCFSFHETKNYTAGGEGGATLINDRTLIERAEIIREKGTNRSQFFR
                     GQVDKYTWRDIGSSYLMSDLQAAYLWAQLEAADRINQQRLSLWQTYYDALTPLARAGR
                     IELPSIPENCGHNAHMFYIKLRDIADRSALINFLKEAEIMAVFHYIPLHDCPAGDKFG
                     EFIGDDVYTTKESERLLRLPLFYNLAPVDQRTVITTLLNYFS"
     gene            complement(7876..8553)
                     /gene="rffC"
                     /locus_tag="OPV72_000247"
                     /gene_synonym="wecD"
     CDS             complement(7876..8553)
                     /gene="rffC"
                     /locus_tag="OPV72_000247"
                     /gene_synonym="wecD"
                     /EC_number="2.3.1.210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026256.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-amino-4,6-dideoxy-D-galactose
                     acyltransferase"
                     /protein_id="HCR9912658.1"
                     /translation="MPVRASIEPLHWENTFFGVNSGIVRIDASAPELTPEALQAWQRV
                     QAKVPAENIAWLSALQSLGFSLVEGEVDFALPVKGHRDQHGAEIAHLTDIPALRQLAG
                     EAFTQSRFRAPWYAPDASARFYAQWIENAVRGTFDHQCLVLRTETGAIRGYVSLRELN
                     DTDVRIGLLAGRGAGAELMQAAICWAQSRGKATLRVATQLGNTAALKRYIQSGANIES
                     TAYWLYR"
     gene            complement(8531..9412)
                     /gene="rfbA"
                     /locus_tag="OPV72_000248"
     CDS             complement(8531..9412)
                     /gene="rfbA"
                     /locus_tag="OPV72_000248"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HCR9912659.1"
                     /translation="MKGIILAGGSGTRLHPITRGVSKQLLPVYDKPMIYYPLSVLMLA
                     GIREILIITTPEDKRDFQRLLGDGAAFGIDLHYAEQPSPDGLAQAFIIGETFLNGEPS
                     CLVLGDNIFFGQGFSPKLRQVAARTEGATVFGYQVMDPERFGVVEFDDDFRALSLEEK
                     PKQPKSNWAVTGLYFYDSKVVEYAKRVKPSGRGELEITSINQMYLEEGKLTVELLGRG
                     FAWLDTGTHDSLIEASTFVQTVEKRQGFKIACLEEIAWRNGWLDDDGLKRAASQLEKT
                     GYGQYLLELLRARPRQY"
     gene            complement(9445..10512)
                     /gene="rffG"
                     /locus_tag="OPV72_000249"
     CDS             complement(9445..10512)
                     /gene="rffG"
                     /locus_tag="OPV72_000249"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HCR9912660.1"
                     /translation="MKRILVTGGAGFIGSAVVRHIIHETADAVVVVDKLTYAGNLMSL
                     ASVAQSDRFAFEKVDICDRASLEQVFQQYQPDSVMHLAAESHVDRSIDGPAAFIETNI
                     VGTYTLLEAARAYWSALDADAKAAFRFHHISTDEVYGDLHTADDFFTETTPYAPSSPY
                     SASKASSDHLVRAWLRTYGLPTLVTNCSNNYGPYHFPEKLIPLMILNALAGKPLPVYG
                     NGQQIRDWLYVEDHARALYHVVTNGAVGETYNIGGHNERKNLDVVRTICALLEELAPQ
                     KPQGVANYHDLITFVDDRPGHDLRYAIDASKIARELGWTPQETFESGMRKTVQWYLAN
                     EAWWKPVQDGSYQGERLGLKR"
     gene            complement(10512..11774)
                     /gene="wecC"
                     /locus_tag="OPV72_000250"
     CDS             complement(10512..11774)
                     /gene="wecC"
                     /locus_tag="OPV72_000250"
                     /EC_number="1.1.1.336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetyl-D-mannosamine dehydrogenase"
                     /protein_id="HCR9912661.1"
                     /translation="MSFTTISVIGLGYIGLPTAAAFASRQKQVIGVDINQHAVDTINR
                     GEIHIVEPALGNVVKMAVEGGFLRATTTPVEADAYLIAVPTPFKGDHDPDMAYVEAAA
                     KSIAPVLKKGALVILESTSPVGATEQMAGWLAGMRPDLTFPQQAGEQADVNIAYCPER
                     VLPGQVMVELIKNDRVIGGMTPVCSARASALYKIFLEGECVVTNSRTAEMCKLTENSF
                     RDVNIAFANELSLICAEQGINVWELIRLANRHPRVNILQPGPGVGGHCIAVDPWFIVA
                     QNPQQARLIRTAREVNDGKPHWVVDQVKAAVADCLAATDKRASEVKIACFGLAFKPNI
                     DDLRESPAMGIAQSIARWHSGETLVVEPNIRQLPKKLDGLCTLAKLDAALAAADVLVM
                     LVDHDEFKAIPGDAVHQRYVVDTKGVWR"
     gene            complement(11771..12901)
                     /gene="wecB"
                     /locus_tag="OPV72_000251"
     CDS             complement(11771..12901)
                     /gene="wecB"
                     /locus_tag="OPV72_000251"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HCR9912662.1"
                     /translation="MKVLTVFGTRPEAIKMAPLVHALEKDPHFEAKVCVTAQHREMLD
                     QVLTLFSIVPDYDLNIMQPGQGLTEITCRILERLKPILADFKPDVVLVHGDTTTTIAT
                     SLAAFYQRIPVGHVEAGLRTGDLYSPWPEEANRTLTGHLAMYHFAPTENSRQNLLREN
                     IPDERIFVTGNTVIDALIWVRDRVLTSDTLQAELAEQYPFLNANKKMILVTGHRRESF
                     GQGFEHICQALAEIAAANQNVQIVYPVHLNPNVSEPVNRILGHVENVVLIEPQDYLPF
                     VWLMNHAWLILTDSGGIQEEAPSLGKPVLVMRETTERPEAITAGTVRLIGTDSRRIVA
                     EVMRLLHDENEYQTMSRAHNPYGDGQSCARILQALKSYRVSL"
     gene            complement(12957..14003)
                     /gene="wzzE"
                     /locus_tag="OPV72_000252"
     CDS             complement(12957..14003)
                     /gene="wzzE"
                     /locus_tag="OPV72_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECA polysaccharide chain length modulation
                     protein"
                     /protein_id="HCR9912663.1"
                     /translation="MTQPLPGARAVSAENELDIRGLFRTLWAGKFWIIGIGLLFALIA
                     LAYTFFARQEWSATAITDRPTVNMLGGYYSQQQFLRNLDIKTDPASSDKPSVMDEAYK
                     EFIMQLASWDTRRDFWLQTDYYKQRMVGNSKADAVMLDELINNIQFTPGDFTRAINDN
                     VRLIAETAPDANNLLRQYVAFASQRAASHLNDELKGAWAARTVQMKAQVKRQEEVAKA
                     IYSRRVNSIEQALKIAEQHNISRSATDVPADELPDSELFLLGRPMLQARLENLQAVGP
                     AFDLDYFQNRAMLNTLNVGPTLDPRFQTYRYLRTPEEPVKRDSPRRAFLMIMWGIVGA
                     LIGAGVALTRRRTI"
     gene            complement(14015..15118)
                     /gene="wecA"
                     /locus_tag="OPV72_000253"
     CDS             complement(14015..15118)
                     /gene="wecA"
                     /locus_tag="OPV72_000253"
                     /EC_number="2.7.8.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--undecaprenyl-phosphate
                     N-acetylglucosaminephosphotransferase"
                     /protein_id="HCR9912664.1"
                     /translation="MKLLTALSELISIFLFTTIFIFLARKVAIKIGLVDKPNFRKRHQ
                     GVIPLVGGISVFAGICFMFGLSDYYIPHLSLYLICAGVLVFVGAMDDRFDISVKIRAV
                     VQAVIAVVMMVIAKLHLGSLGYIFGPWELVLGPFGYFLTLFAVWAAINAFNMVDGIDG
                     LLGGLSSVSFAAMGLILWFDGQTSLAMWCFAMIAAILPYIMLNLGILGRRYKVFMGDA
                     GSTLIGFTVIWLLLETTQGKTHSISPVTALWIIAIPLMDMVAIMYRRLRKGMSPFSPD
                     RQHIHHLVMRAGFTSRQAFVLITLAAAILAGVGVTAEYSHFVPEWVMLVLFLLAFFLY
                     GYCIKRAWKVARFIKRVKRRLRRQRKNRPNLTK"
     gene            complement(15348..16607)
                     /gene="rho"
                     /locus_tag="OPV72_000254"
     CDS             complement(15348..16607)
                     /gene="rho"
                     /locus_tag="OPV72_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017492510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HCR9912665.1"
                     /translation="MNLTELKNTPVSELITLGESMGLENLARMRKQDIIFAILKQHAK
                     SGEDIFGDGVLEILQDGFGFLRSADSSYLAGPDDIYVSPSQIRRFNLRTGDTISGKIR
                     PPKEGERYFALLKVNEVNYDKPENARNKILFENLTPLHANSRLRMERGNGSTEDLTAR
                     VLDLASPIGRGQRGLIVAPPKAGKTMLLQNIAQSIAYNHPDCVLMVLLIDERPEEVTE
                     MQRLVKGEVVASTFDEPASRHVQVAEMVIEKAKRLVEHKKDVIILLDSITRLARAYNT
                     VVPASGKVLTGGVDANALHRPKRFFGAARNVEEGGSLTIIATALIDTGSKMDEVIYEE
                     FKGTGNMELHLSRKIAEKRVFPAIDYNRSGTRKEELLTTQEELQKMWILRKIIHPMGE
                     IDAMEFLINKLAMTKTNDDFFEMMKRS"
     gene            complement(16695..16829)
                     /locus_tag="OPV72_000255"
     CDS             complement(16695..16829)
                     /locus_tag="OPV72_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rho operon leader peptide"
                     /protein_id="HCR9912666.1"
                     /translation="MWFYPSLPVFSRTRSGKIPGSSLIPSCRFSSAYFPVTRQRTDMS
                     "
     gene            complement(17026..17355)
                     /gene="trxA"
                     /locus_tag="OPV72_000256"
     CDS             complement(17026..17355)
                     /gene="trxA"
                     /locus_tag="OPV72_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017375425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin TrxA"
                     /protein_id="HCR9912667.1"
                     /translation="MSDKIIHLTDDSFDTDVLKADGAILVDFWAEWCGPCKMIAPILD
                     EIADEYQGKLTVAKLNIDQNPGTAPKYGIRGIPTLLLFKNGEVAATKVGALSKGQLKE
                     FLDANLA"
     gene            17499..18764
                     /gene="rhlB"
                     /locus_tag="OPV72_000257"
     CDS             17499..18764
                     /gene="rhlB"
                     /locus_tag="OPV72_000257"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase RhlB"
                     /protein_id="HCR9912668.1"
                     /translation="MSKTHLTEQKFSDFALHPQVVEALEKKGFYNCTPIQALALPLTL
                     AGRDVAGQAQTGTGKTMAFLTSTFHYLLSHPAIDDRKVNQPRALIMAPTRELAVQIHA
                     DAEPLAQATGLKLGLAYGGDGYDKQLKVLESGVDILIGTTGRLIDYAKQNHINLGAIQ
                     VVVLDEADRMYDLGFIKDIRWLFRRMPPAAQRLNMLFSATLSYRVRELAFEQMNNAEY
                     VEVEPEQKTGHRIKEELFYPSNEEKMRLLQTLIEEEWPDRAIIFANTKHRCEDIWGHL
                     AADGHRVGLLTGDVAQKKRLRILDEFTRGDLDILVATDVAARGLHIPAVTHVFNYDLP
                     DDCEDYVHRIGRTGRAGASGHSISLACEEYALNLPAIESYIGHSIPVSKYNPEALMND
                     LPKPLRLTRSRPGNGPRRAGAPRNRRRSG"
     gene            18883..20364
                     /gene="gppA"
                     /locus_tag="OPV72_000258"
     CDS             18883..20364
                     /gene="gppA"
                     /locus_tag="OPV72_000258"
                     /EC_number="3.6.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanosine-5'-triphosphate,3'-diphosphate
                     diphosphatase"
                     /protein_id="HCR9912669.1"
                     /translation="MNSTSLYAAIDLGSNSFHMLVVREAAGSIQTLTRIKRKVRLAAG
                     LNNDNHLSAEAMERGWQCLRLFAERLQDIPQPQIRVVATATLRLAVNAGEFIAKAQTI
                     LGCPVQVISGEEEARLIYQGVAHTTGGADQRLVVDIGGASTELVTGTGAQTTSLFSLS
                     MGCVTWLERYFSDRNLAQENFDDAEKAARDVLRPVADELRFHGWKVCVGASGTVQALQ
                     EIMMAQGMDERITLAKLQQLKQRAIQCGRLEELEIEGLTLERALVFPSGLAILIAIFT
                     ELNIQSMTLAGGALREGLVYGMLHLAVDQDIRSRTLRNIQRRFIVDTDQANRVAKLAD
                     NFLKQVENAWHIEPISRELLLSACQLHEIGLSVDFKQAPYHAAYLVRHLDLPGYTPAQ
                     KKLLATLLLNQTNPVDLSSLHQQNAVPPRVAEQLCRLLRLAILFAGRRRDDLVPEITL
                     QALNENLTLTLPGDWLAHHPLGKELIDQESQWQSYVHWPLDVR"
     gene            complement(20404..22428)
                     /gene="rep"
                     /locus_tag="OPV72_000259"
     CDS             complement(20404..22428)
                     /gene="rep"
                     /locus_tag="OPV72_000259"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase Rep"
                     /protein_id="HCR9912670.1"
                     /translation="MRLNPGQQHAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCG
                     YQARHIAAVTFTNKAAREMKERVGQTLGRKEARGLMISTFHTLGLDIIKREYAALGMK
                     SNFSLFDDTDQVALLKELTEGLIEDDKVLLQQLISTISNWKNDLKTPAQAAAGAKGER
                     DRIFAHCYGLYDAHMKACNVLDFDDLILLPTLLLQRNDEVRERWQNKIRYLLVDEYQD
                     TNTSQYELVKLLVGQRARFTVVGDDDQSIYSWRGARPQNLVLLSQDFPALQVIKLEQN
                     YRSSGRILKAANILIANNPHVFEKRLFSELGYGAELKVLSANNEEHEAERVTGELIAH
                     HFVNKTQYKDYAILYRGNHQSRVFEKFLMQNRIPYKISGGTSFFSRPEIKDLLAYLRV
                     LTNPDDDSAFLRIVNTPKREIGPATLQKLGEWAMTRNKSLFTASFDMGLSQKLTGRGY
                     DSLTRFTHWLGEIQRLAEREPVAAVRDLIHGIDYESWLYETSPSPKAAEMRMKNVNQL
                     FSWMTEMLEGNELDEPMTLTQVVTRFTLRDMMERGESEEELDQVQLMTLHASKGLEFL
                     YVYMVGMEEGFLPHQSSIDEDNIEEERRLAYVGITRAQKELTFTLCKERRQYGELVRP
                     EPSRFLLELPQDDLIWEQERKVVSAEERMQKGQSHLANLKAMMAAKRAKS"
     gene            complement(22528..23256)
                     /locus_tag="OPV72_000260"
     CDS             complement(22528..23256)
                     /locus_tag="OPV72_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016506088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HCR9912671.1"
                     /translation="MDFFSINNVMVNIPLGEGGYALSWIEAIGTVFGLLCIWCASREK
                     IINYLFGLINVTLFAAIFFQIQLYASLLLQVFFFAANIYGWYAWSRQNDAREAALKVR
                     WLSCQQTWRLGGICIISILLMTWFIDPVFAMLTRVMLALLQTVGMQVAMPELQPDAFP
                     FWDSTMLVLSIAAMVLMTRKYVENWLLWVIIDVISVVIYAVQGVYAMSLEYVLLTVIA
                     LMGSYSWIKSAQRNGYTSLAARAC"
     gene            complement(23256..23999)
                     /locus_tag="OPV72_000261"
     CDS             complement(23256..23999)
                     /locus_tag="OPV72_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001182423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HCR9912672.1"
                     /translation="MQPHIRLNTSMTRAKYALLPGDPGRVDRIARFLDKAEILGQNRE
                     FRAARGWYQGVEIVVLSTGIGGPSTAIAIEELRQVGVNTLIRIGSCGALQDSLALGDV
                     IIAHGAVADDGASKTYAPASYPACADPYLTATLIQQAKQMNISAVCGLVRSHDSFYTD
                     REAELDAEWSARGVLGADMETAALMVVGALRGLRTASLLNVVVAHSGCLESSINHYVQ
                     QETLCQQGEERQISLALQAIYFDSLQGEQ"
     gene            complement(24027..24728)
                     /locus_tag="OPV72_000262"
                     /pseudo
     CDS             complement(24027..24728)
                     /locus_tag="OPV72_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004127355.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
     gene            24922..25203
                     /gene="ppiC"
                     /locus_tag="OPV72_000263"
     CDS             24922..25203
                     /gene="ppiC"
                     /locus_tag="OPV72_000263"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PpiC"
                     /protein_id="HCR9912673.1"
                     /translation="MAKMAAALHILVKEEKLALDLLEQIKNGGDFEKLAKKHSICPSG
                     KKGGHLGEFRQGQMVPAFDKVVFSCPVLEPTGPLHTQFGYHIIKVLYRK"
     gene            complement(25295..26770)
                     /gene="ilvC"
                     /locus_tag="OPV72_000264"
     CDS             complement(25295..26770)
                     /gene="ilvC"
                     /locus_tag="OPV72_000264"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HCR9912674.1"
                     /translation="MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVG
                     CGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLV
                     VNLTPDKQHSDVVRSVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTE
                     VREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDL
                     MGEQTILCGMLQAGSLLCFDKLVAEGTDPAYAEKLIQFGWETITEALKQGGITLMMDR
                     LSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLLTWREET
                     GKTAFETAPQFEGKIGEQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLH
                     ELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYACVPLLKPFMAELQPGDLGSAIPE
                     GAVDNAQLRDVNDAIRSHAIEQVGKKLRGYMTDMKRIAVAG"
     gene            26935..27822
                     /gene="ilvY"
                     /locus_tag="OPV72_000265"
     CDS             26935..27822
                     /gene="ilvY"
                     /locus_tag="OPV72_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator IlvY"
                     /protein_id="HCR9912675.1"
                     /translation="MDLRDLKTFLHLAESRHFGRSARAMHVSPSTLSRQIQRLEEDLG
                     QPLFVRDNRTVTLTEAGEELRVFAQQTLLQYQQLRHTLDQQGPSLSGELHIFCSVTAA
                     YSHLPPILDRFRAEHPSVEIKLTTGDAADAMEKVVTGEADLAIAGKPETLPGAVAFSM
                     LENLAVVLIAPALPCPVRNQVSVDKPDWSTVPFIMADQGPVRRRIELWFRRHKISNPQ
                     IYATVGGHEAMVSMVALGCGVALLPEVVLENSPEPVRNRVMILERSDEKTPFELGVCA
                     QKKRLHEPLIDAFWKILPN"
     gene            complement(27825..28166)
                     /locus_tag="OPV72_000266"
     CDS             complement(27825..28166)
                     /locus_tag="OPV72_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HCR9912676.1"
                     /translation="MIAKTDSDFRHVTPSGGNVFADLGFHKQDAEKFYADSLNEIENT
                     LAIKQQLMEEITLWITQNQMKQAEVATVLHISRPRVSDVVNKKCSKFTIDALVNMLSR
                     IGKPVRVMVGP"
     gene            complement(28163..28480)
                     /locus_tag="OPV72_000267"
     CDS             complement(28163..28480)
                     /locus_tag="OPV72_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HCR9912677.1"
                     /translation="MGSSLEDLLAFPITVRKAVGYQLHKIQYGIEPDDWKPFSEIGAG
                     VNEIRIRNNNGIYRVMYVANFAEALYVLHSFQKQTQQTSQHDKNIARTRYNRVVQQRR
                     NSL"
     gene            complement(28761..30305)
                     /gene="ilvA"
                     /locus_tag="OPV72_000268"
     CDS             complement(28761..30305)
                     /gene="ilvA"
                     /locus_tag="OPV72_000268"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase, biosynthetic"
                     /protein_id="HCR9912678.1"
                     /translation="MAESQPLSVAPEGAEYLRAVLRAPVYEAAQVTPLQKMEKLSSRL
                     DNVILVKREDRQPVHSFKLRGAYAMMAGLTEEQKAHGVITASAGNHAQGVAFSSARLG
                     VKSLIVMPKATADIKVDAVRGFGGEVLLHGANFDEAKAKAIELAQQQGFTWVPPFDHP
                     MVIAGQGTLALELLQQDSHLDRVFVPVGGGGLAAGVAVLIKQLMPQIKVIAVEAEDSA
                     CLKAALEAGHPVDLPRVGLFAEGVAVKRIGDETFRLCQEYLDDIITVDSDAICAAMKD
                     LFEDVRAVAEPSGALALAGMKKYIAQHNIRGERLAHVLSGANVNFHGLRYVSERCELG
                     EQREALLAVTIPEEKGSFLKFCQLLGGRMVTEFNYRFADAKHACIFVGVRVSQGLEER
                     KEIITQLCDGGYSVVDLSDDEMAKLHVRYMVGGRPSKPLQERLYSFEFPESPGALLKF
                     LHTLGTHWNISLFHYRSHGTDYGRVLAAFELGDHEPDFETRLHELGYECHDESNNPAF
                     RFFLAG"
     gene            complement(30308..32158)
                     /gene="ilvD"
                     /locus_tag="OPV72_000269"
     CDS             complement(30308..32158)
                     /gene="ilvD"
                     /locus_tag="OPV72_000269"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HCR9912679.1"
                     /translation="MPKYRSATTTHGRNMAGARALWRATGMTDSDFGKPIITVVNSFT
                     QFVPGHVHLRDLGKLVAEQIEASGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIAD
                     SVEYMVNAHCADAMVCISNCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDQII
                     KLDLVDAMIQGADPKVSDDQSNQVERSACPTCGSCSGMFTANSMNCLIEALGLSQPGN
                     GSLLATHADRKQLFLNAGKRIVELTKRYYEQDDESALPRNIANKAAFENAMTLDIAMG
                     GSTNTVLHLLAAAQEAEIDFTMSDIDKLSRKVPQLCKVAPSTQKYHMEDVHRAGGVLG
                     ILGELDRAGLLNRNVKNVLGLTLPQTLEQYDITVTQDEAVKKMFRAGPAGIRTTQAFS
                     QDCRWDSLDDDRAAGCIRSLEYAYSKDGGLAVLYGNFAENGCIVKTAGVDDSILKFTG
                     PVKVYESQDDAVEAILGGKVVEGDVVVIRYEGPKGGPGMQEMLYPTSFLKSMGLGKAC
                     ALITDGRFSGGTSGLSIGHVSPEAASGGTIALIEDGDTIAIDIPNRSIQLQLSEAEIA
                     ARREAQEARGDKAWTPKNRQRQVSFALRAYASLATSADKGAVRDKSKLGG"
     gene            complement(32315..33244)
                     /gene="ilvE"
                     /locus_tag="OPV72_000270"
     CDS             complement(32315..33244)
                     /gene="ilvE"
                     /locus_tag="OPV72_000270"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain-amino-acid transaminase"
                     /protein_id="HCR9912680.1"
                     /translation="MTTKKADYIWFNGEMVRWEDAKVHVMSHALHYGTSVFEGIRCYD
                     SHKGPVVFRHREHMQRLRDSAKIYRFPVSQSIDELMEACRDVIRKNNLTSAYIRPLVF
                     VGDVGMGVNPPPGYTTDVIIAAFPWGAYLGAEALDQGIDAMVSSWNRAAPNTIPTAAK
                     AGGNYLSSLLVGSEARRHGYQEGIALDVNGYISEGAGENLFEVKDGVLFTPPFTSSAL
                     PGITRDAIIKLAKELGIEVREQVLSRESLYLADEVFMSGTAAEITPVRSVDGIQVGEG
                     RCGPVTKRIQQAFFGLFTGETEDKWGWLDPVNS"
     gene            complement(33262..33525)
                     /gene="ilvM"
                     /locus_tag="OPV72_000271"
     CDS             complement(33262..33525)
                     /gene="ilvM"
                     /locus_tag="OPV72_000271"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase 2 small subunit"
                     /protein_id="HCR9912681.1"
                     /translation="MMQHQVNVSARFNPETLERVLRVVRHRGFQVCSMNMEAATDAQN
                     INIELTVASPRSVDLLFSQLSKLVDVAHVAICQSAATSQQIRA"
     gene            complement(33522..35168)
                     /locus_tag="OPV72_000272"
     CDS             complement(33522..35168)
                     /locus_tag="OPV72_000272"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase 2 catalytic subunit"
                     /protein_id="HCR9912682.1"
                     /translation="MNGAQWVVHALRAQGVKTVFGYPGGAIMPVYDALYDGGVEHLLC
                     RHEQGAAMAAIGYARSTGKTGVCIATSGPGATNLITGLADALLDSVPVVAITGQVSAP
                     FIGTDAFQEVDVLGLSLACTKHSFLVQSLAELPRIMAEAFEVANAGRPGPVLVDIPKD
                     IQLASGELEPWFTTVDNEATFPQADVEQARQMLEQAKKPMLYVGGGVGMAKAVPALRK
                     FIAVTQMPVTCTLKGLGAVEADYPYYLGMLGMHGTKAANFAVQECDLLIAVGARFDDR
                     VTGKLNTFAPNASVIHMDIDPAEMNKLRQAHVALQGDLNSLLPALQQPLKIDAWRQSC
                     AELRAEHAWRYDHPGETIYAPLLLKQLSERKPADSVVTTDVGQHQMWSAQHMTYTRPE
                     NFITSSGLGTMGFGLPAAVGAQVARPNDTVICISGDGSFMMNVQELGTVKRKQLPLKI
                     VLLDNQRLGMVRQWQQLFFQERYSETTLTDNPDFLMLASAFGIPGQHITRKDQVEAAL
                     DTMLASEGPYLLHVSIDELENVWPLVPPGASNSEMLEKLS"
     gene            complement(35171..35221)
                     /locus_tag="OPV72_000273"
     CDS             complement(35171..35221)
                     /locus_tag="OPV72_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9912683.1"
                     /translation="MNNSIKFCFSRFTTGM"
     gene            complement(35308..35406)
                     /gene="ilvL"
                     /locus_tag="OPV72_000274"
     CDS             complement(35308..35406)
                     /gene="ilvL"
                     /locus_tag="OPV72_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ilv operon leader peptide"
                     /protein_id="HCR9912684.1"
                     /translation="MTALLRVISLVVISVVVIIIPPCGAALGRGKA"
     gene            35758..35958
                     /locus_tag="OPV72_000275"
                     /pseudo
     CDS             35758..35958
                     /locus_tag="OPV72_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462790.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium chelatase"
     gene            complement(36032..37084)
                     /locus_tag="OPV72_000276"
     CDS             complement(36032..37084)
                     /locus_tag="OPV72_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001544402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCR9912685.1"
                     /translation="MAVRKLTTGKWLCECYPAGRSGRRVRKQFATKGEALAFERHTME
                     ETESKPWLGESVDRRTLKDVVELWFKLHGKSLTAGQHVYDKLLLMVDALGNPLATDLT
                     SKMFAHYRDKRLTGEIYFSEKWKKGASPVTINLEQSYLSSVFSELSRLGEWSYPNPLE
                     NMRKFTIAEKEMAWLTHEQIVELLADCKRQDPILALVVKICLSTGARWREAVNLTRSQ
                     VTKYRITFVRTKGKKNRSIPISKELYEEIMALDGFNFFTDCYFQFLSVMEKTSIVLPR
                     GQLTHVLRHTFAAHFMMSGGNILALQKILGHHDIKMTMRYAHLAPDHLETALRFNPLA
                     TLPSGDKVAAAVGITP"
     gene            complement(37273..37464)
                     /locus_tag="OPV72_000277"
     CDS             complement(37273..37464)
                     /locus_tag="OPV72_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001513672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9912686.1"
                     /translation="MLGKVFFVVLSCSLLLNPLTTYARNYPCSGKKGGVSHCTSDGKF
                     VCNDGTISKSKKICTKNSR"
     gene            complement(37480..38049)
                     /locus_tag="OPV72_000278"
     CDS             complement(37480..38049)
                     /locus_tag="OPV72_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein CI"
                     /protein_id="HCR9912687.1"
                     /translation="MNLEKGGRGAIERMVEAYGFKTRQALCDHLGISKSTLATRYMRD
                     SFPAEWVIQCALETGTSLNWLTTGHGSKQTSGNTNTMEVAKYVLSDGALREDGFYIFD
                     KGFLPSTFKKPFVITDNNSEFICDKEFDDIRDGKWVISIDGEVTIRDITRLPGGRIFV
                     EGGNRAFECKIEDIEIIGKIISLTVKYVK"
     gene            38175..38396
                     /locus_tag="OPV72_000279"
     CDS             38175..38396
                     /locus_tag="OPV72_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulator"
                     /protein_id="HCR9912688.1"
                     /translation="MRPNISITLTTPHVTIERYSELTGLSIDTINDMLADGRLICHRL
                     RKDKKREKVMINIAAMTVDALSECNLNLN"
     gene            38429..38938
                     /locus_tag="OPV72_000280"
     CDS             38429..38938
                     /locus_tag="OPV72_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory CII family protein"
                     /protein_id="HCR9912689.1"
                     /translation="MFDYQVSKHPHFDEACRAFALRHNLVQLAERAGMNVQILRNKLN
                     PAQPHLLTAPEIWLLTDLTEDSTLVDGFLAQIHCLPCVPINEVAKEKLPHYVMSATAE
                     IGRVAAGAVSGDVKTSAGRRDAISSINSVTRLMALAAVSLQARLQANPAMASAVDTVT
                     GLGASFGLL"
     gene            38946..39242
                     /locus_tag="OPV72_000281"
     CDS             38946..39242
                     /locus_tag="OPV72_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2724 domain-containing protein"
                     /protein_id="HCR9912690.1"
                     /translation="MLTKEPSFASLLVKQSPAMHYGHGWIMGEDGKRWHPCHSQDELL
                     SELTTRKRRKSKCMQRKVKWFISFVTEGRVIQYLKMICSVVIRRCRAMAVTFSR"
     gene            39360..39701
                     /locus_tag="OPV72_000282"
     CDS             39360..39701
                     /locus_tag="OPV72_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5347 domain-containing protein"
                     /protein_id="HCR9912691.1"
                     /translation="MAINGAAATVPLSPGERLNGLNHIAELRAKVFGLNIESELERFI
                     KDMRDPRDINNEQNKRALAAIFFMAKIPAERHSISINELTTDEKRELIKAMNHFRAVV
                     SLFPRRLTMPN"
     gene            39769..40002
                     /locus_tag="OPV72_000283"
     CDS             39769..40002
                     /locus_tag="OPV72_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2732 domain-containing protein"
                     /protein_id="HCR9912692.1"
                     /translation="MRNIETLSTKTGPDDAGLNILLTEARLEERRARAEAMVARLDSL
                     ACHITSRQLTHVEAAELLRVTAEAIQNEAQEIH"
     gene            40002..40229
                     /locus_tag="OPV72_000284"
     CDS             40002..40229
                     /locus_tag="OPV72_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA family transcriptional regulator"
                     /protein_id="HCR9912693.1"
                     /translation="MADAMDLVQQRVEEERQRHIRAARAKTPGVSRVLCIECEAPIPP
                     ARRRAIPGVQLCITCQEIAELKGKHYNGGAV"
     gene            40226..41083
                     /locus_tag="OPV72_000285"
     CDS             40226..41083
                     /locus_tag="OPV72_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000104187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HCR9912694.1"
                     /translation="MSTILKWAGNKTAIMSELKKHLPAGPRLVEPFAGSCAVMMETDY
                     PSYLVADINPDLINLYKKVAADCESFISRARVLFEIANREVAYYNIRQEFNYSTEITD
                     FMKAVYFLYLNRHGYRGLCRYNKSGHFNIPYGNYKNPYFPEKEIRAFAEKAQQATFIC
                     ASFDETLAMLQVGDVVYCDPPYDGTFSGYHTNGFTEDDQYHLASVLEYRSSEGHPVIV
                     SNSDTSLIRSLYRNFTHHYIKAKRSIGVSAGESKSATEIIAVSGARCWVGFDPSRGVD
                     SSAVYGVRA"
     gene            41080..43494
                     /locus_tag="OPV72_000286"
     CDS             41080..43494
                     /locus_tag="OPV72_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication endonuclease"
                     /protein_id="HCR9912695.1"
                     /translation="MSHADMNNCSGFNEAAAAFSWNSPKKAINPYLDLAEVAPVSALS
                     NLITLYAADNEQEQLRREALSDQVWERYFFNESRDPVQREMEQDKFISRAKLAHEQQR
                     FNPDMVILADVNAQPSHISRPLMQRIEYFSSLGRPKAYSRYLRETIKPCLERLEHVRD
                     SQLSTSFRFMASHEGLDGLLILPEMSQDQVKRLSTLVAAHMSMCLDAACGDLYATDDV
                     KPEEIRKTWEKVAAETLRLDVIPPAFEQLRRKRNRRKPVPYELIPGSLARMLCADWWY
                     RKLWKMRCEWREEQLRAVCLVSKKASPYVSYEAMMHKREQRRKSLEFFRSHELVNEDG
                     DTLDMEDVVNASSSNPAHRRNEMMACVKGLELIAEMRGDCAVFYTITCPSRFHSTLNN
                     GRPNPTWTNTTVRQSSDYLVGMFAAFRKAMHKAGLRWYGVRVAEPHHDGTVHWHLLCF
                     MRKKDRRTITALLRKFAIREDREELGNNTGPRFKSELINPRKGTPTSYIAKYISKNID
                     GRGLAGEISKETGKSLRDNAEYVNAWASLHRVQQFRFFGIPGRQAYRELRLLAGQAAR
                     QQGDKKAGAPVLDNPRLDAILAAADAGCFATYIMKQGGVLVPRKYHLIRTAYEINEEP
                     TAYGDHGIRIYGIWSPIAEGKICTHAVKWKMVRKAVDVQEAAADQGACAPWTRGNNCP
                     LAENLNQHEKDKSADGDTRTDITCMDDKELHDYLHSMGKKEHRELAARLRLVKPKRRK
                     DHKQRITEHQRQQLVYELKSRGFDGSEKEVDLLLRGGSIPSGAGLRIFYRNQRLQEDD
                     KWRDLY"
     gene            43648..43836
                     /locus_tag="OPV72_000287"
     CDS             43648..43836
                     /locus_tag="OPV72_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9912696.1"
                     /translation="MQDYFLESLKLQRIDFFLKLVAASECSDEEKGLALQWVSELTDE
                     LMAKIRSHEYSRSMDVIS"
     gene            complement(43904..44203)
                     /locus_tag="OPV72_000288"
     CDS             complement(43904..44203)
                     /locus_tag="OPV72_000288"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9912697.1"
                     /translation="MKRITFSFTLVAIIIALAGCALPDKDGDFGAYVHTCQQYAYGKS
                     YAFENRDFAYKVCKDAAKLWSDEVPGYVIRQIQLHPEIPSEEIKYAAMAGSLGNN"
     gene            complement(44312..45190)
                     /locus_tag="OPV72_000289"
     CDS             complement(44312..45190)
                     /locus_tag="OPV72_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001251691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9912698.1"
                     /translation="MAMSLSCQLILLGLALFFYDWDRDMKKLTGVIAFALLLTACDKP
                     KIDASSDQSMKESIQKVRESLPADKKAQFDDAVKVVAFSQINMRELMQAGTSSGDVYE
                     TKIKSALEGKTGDEVINYAQTIRLEREKREKEQALQEIKELEAKQTSATQAAEKMKAF
                     KVERSRFYFQKEDYGNDQPILDISVENGTDKAVARVFFKGVIASPGRSVPWFSDVFNY
                     KISGGLEPGEKANWKLAPNRYSDWGKLKVPADAIFTVTVIGLEDADGKSIYGDAEFSE
                     RDADRLNQLRDKYLSK"
     gene            45804..46718
                     /locus_tag="OPV72_000290"
     CDS             45804..46718
                     /locus_tag="OPV72_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9912699.1"
                     /translation="MPYQLVELSPVANDLEQLGTKEKFWFYFSDDTVNLQLFKYSRLG
                     TGEHWSEKCAAELCHLLNIPHASYDLARYNGRFGVVTQNIIPSGFRMVMGNEVLHSST
                     FDYPGPLQAGEKPVRVREHTVTRVLGCLDRESIKPPPSVYDLTGLNAADVFCGFLMLD
                     ALVSNQDRHHENWAIMLNNETGEQFLCPTYDHAASLGREMLDDERNERLNTKDKNRQI
                     PCFVRKARSELFKAKTDKKPLLTVEAFQHAVEGRVAARDHWLGKLSVLTEDSITDVFN
                     QVPSSCISDSARRFATLMVMENRRRLLE"
     gene            46715..47455
                     /locus_tag="OPV72_000291"
     CDS             46715..47455
                     /locus_tag="OPV72_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HCR9912700.1"
                     /translation="MTNTNSVYVAWQAPDTRDWHVVGNLQERKSGYVFRYTKGALKST
                     KFTKFSGMSDVRETYVSEELFPLFKNRLLSPRRPEYPSFIKWLGFEEDKVNPIDILAR
                     SGGLRSTDQLQIFKKIDVDSDGNFEHFFFLHGLGYLNSLANARVSELKPGQILRLCLD
                     LQNEYDGDAVVVRADKPAEIVGYCPRYLSNDIKKMLLDDPKSITLTVEKISDDAPHNY
                     RLLCKLSGVLSQACQSTLIPQDEFEPIE"
     gene            complement(47490..48527)
                     /locus_tag="OPV72_000292"
     CDS             complement(47490..48527)
                     /locus_tag="OPV72_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001419999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HCR9912701.1"
                     /translation="MGKRKKNRAAAMNQIQHKSQTSAEAFSFGDPVPVLDRRELLDYV
                     ECVQMDRWYEPPVSFDGLARTFRAAVHHSSPIAVKCNILTSTYIPHPLLSQQAFSRFV
                     QDYLVFGNAYLEKRTNRFGEIIALEPALAKYTRRGLDLDTYWFVQYGMTTQPYQFTKG
                     SIFHLMEPDINQEIYGLPGYLSAIPSALLNESATLFRRKYYINGSHAGFIMYMTDAAQ
                     NQEDVNNLRNAMKSAKGPGNFRNLFMYSPNGKKDGLQIIPLSEVAAKDEFLNIKNVSR
                     DDMMAAHRVPPQMMGIMPNNVGGFGDVEKASRVFVRNELMPLQKRLQEMNDWLGKEAI
                     QFNTYSLDIVP"
     gene            complement(48527..50293)
                     /locus_tag="OPV72_000293"
     CDS             complement(48527..50293)
                     /locus_tag="OPV72_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase ATPase subunit family protein"
                     /protein_id="HCR9912702.1"
                     /translation="MNTTLTPADLDPRRQAMLLYFQGYRVARIAEMLGEKVATVHSWK
                     KRDKWGDYGPLDQMQLTTAARYCQLIMKEHKEGKDFKEIDLLARQSERHARIGKFNNG
                     GNEADLNPNVANRNKGPRRQPEKNVFTDEQIEKLEEIFHSSMFNYQRHWWEAGKTNRI
                     RNLLKSRQIGATFYFAREALIDALLTGRNQIFLSASKAQAHVFKQYIIDFAKEVEVEL
                     KGDPMVLPNGATLYFLGTNARTAQSYHGNLYLDEYFWIPKFQELRKVASGMAIHKKWR
                     QTYFSTPSSLTHSAYPFWSGALFNRGRNKADKVDIDLSHNNLAPGLLCADGQYRQIVT
                     VEDAVRGGCNLFDLDQLRMEYSPDEYQNLLMCEFVDDLASVFPLSELQACMVDSWEVW
                     TDFHALALRPFGWREVWIGYDPAKGTQNGDSAGCVVVAPPAVPGGKFRILERHQWRGM
                     DFRAQADAIKKLTEQYNVTYIGIDSTGVGHGVYENVKAFFPAVREFVYNPNVKNALVL
                     KAYDIISHRRLEFDAGHTDIAQSFMAIRRATTASGNRPTYEASRSEEASHADLAWATM
                     HALFNEPLQGESANTSNIVEIF"
     gene            50436..51269
                     /locus_tag="OPV72_000294"
     CDS             50436..51269
                     /locus_tag="OPV72_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPO family capsid scaffolding protein"
                     /protein_id="HCR9912703.1"
                     /translation="MTVKAKRFRIGVEGATTDGREIQREWLEQMAASYNPAVYTALIN
                     LEHIKSYLPDSTFNRYGKVTALFAEEITEGPLAGKMALYADVEPTESLVELVKKGQKL
                     FTSMEVSPKFADTGKAYLVGLAATDDPASLGTEMLTFSASAAHNPLANRKQNPANLFT
                     AAEETVIELEEIQEDKLSLFARVTALFTKKEQSDDARFSDVHKAVELVATEQQNLSAR
                     TEKSLSEQEERLSELETALQAQQTAFNELVNKLSHEDSRQDYRQRATGGNAPADTLTN
                     C"
     gene            51286..52344
                     /locus_tag="OPV72_000295"
     CDS             51286..52344
                     /locus_tag="OPV72_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein, P2 family"
                     /protein_id="HCR9912704.1"
                     /translation="MKKNTRFAFNAYLQQLARLNGVAVEELSSKFTVEPSVQQTLEDQ
                     IQQSAAFLTLINVTPVTEQSGQLLGLGVGSTIAGTTDTTAKEREPVDPTLMVDVEYKC
                     EQTNFDTVLTYAKLDLWAKFQDFQVRIRDAIVKRQALDRIMIGFNGVKRAKTSNRSEN
                     PLLQDVNKGWLQKIREDAPDHVMGSTTTGGETTPGAVKVGKGGEYANLDAVVMDAVNE
                     LIDVVYQDDDDLVVICGRELLSDKYFPLVNKEQENSEKLAADMIISQKRMGGLQAVRA
                     PFFPPNALLITRLDNLSIYWQEGTRRRSVIDNPKRDRIENFESVNEAYVVEDYRCAAL
                     VENIQIGDFSAAAAEAGA"
     gene            52348..52998
                     /locus_tag="OPV72_000296"
     CDS             52348..52998
                     /locus_tag="OPV72_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase endonuclease subunit"
                     /protein_id="HCR9912705.1"
                     /translation="MSLSPARQHRLRVQAEQAAREGGSVRHASGYDLMLLQLAEDRRR
                     LKGVQSTVKKAEIKVELLPKYAAWAEGVLAAGGAQQDDVLMYVMLWRIDAGDYAGALE
                     IGRHALRHGWVMPLGNRNVQTVLAEEMADAAQSAMLAATGFDADLLLQTLELTDGLDM
                     PDQSRARLHKAIGAVLSESNPASALNHLNHALQLDPRCGVKKDKQQLERRLRNDSR"
     gene            53094..53558
                     /locus_tag="OPV72_000297"
     CDS             53094..53558
                     /locus_tag="OPV72_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head completion/stabilization protein"
                     /protein_id="HCR9912706.1"
                     /translation="MKFVAPEQAPEQAEIIRNTPFWPDVDLSEFRSMMRTDGTVTQPR
                     LKQVALSAISEVNAELYEFRRRQQMLGYASLAEVPAEQLDGKSERIQHYFNAVYCWAR
                     AMLNERYQDYDATASGVKRGEELAEASGDLWRDARWAISRVQDAPHCTVELI"
     gene            53558..53761
                     /locus_tag="OPV72_000298"
     CDS             53558..53761
                     /locus_tag="OPV72_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail protein X"
                     /protein_id="HCR9912707.1"
                     /translation="MKVRAHQYDTVDALCWRHYGRTQGVTEQVLKANPGLAEYGPFLP
                     HGLQVELPDIPTTTTVQTVQLWD"
     gene            53765..53980
                     /locus_tag="OPV72_000299"
     CDS             53765..53980
                     /locus_tag="OPV72_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9912708.1"
                     /translation="MTLERISAFITYCIAVVLAWLGDLSIKDASTLGGLMIGVLMLAI
                     NWYYKHKAYQLLRDGQISREDYESINR"
     gene            53961..54473
                     /locus_tag="OPV72_000300"
     CDS             53961..54473
                     /locus_tag="OPV72_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme"
                     /protein_id="HCR9912709.1"
                     /translation="MNPSIVKRCLVGAVLAIAATLPGFQQLHTSVEGLKLIADYEGCR
                     LQPYQCSAGVWTDGIGNTSGVIPGKTITERQAAEGLISNVLRVERALERCVKQQPPQK
                     VYDAAVSFAFNVGTGNACSSTLVKLLNQRRWADACRQLPRWVYVKGVFNQGLDNRRAR
                     EMAWCLQGAN"
     gene            54475..54852
                     /locus_tag="OPV72_000301"
     CDS             54475..54852
                     /locus_tag="OPV72_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000730949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9912710.1"
                     /translation="MKKKLISGLFLMLWMALLIAAMVYPQGIFPVLAASGVWVACLLT
                     WAVIPVALAALIKNGPLWQELRASLLKTITRKENVFTSWVMRLLIVVSLAWTGWAITL
                     VFYLLTVIAFWITRNQMAQQVAA"
     gene            54849..55277
                     /locus_tag="OPV72_000302"
     CDS             54849..55277
                     /locus_tag="OPV72_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001341071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysB family phage lysis regulatory protein"
                     /protein_id="HCR9912711.1"
                     /translation="MNRLLLVVLALLLAALGWQTWRLADASQTISTQADELQSKSQAL
                     AKSNSQLISLSILTETNNREQARLYAEAEQTSAQLRQRQRRIEELKRENEDLRHWADT
                     PLPADIIRLRERPALTGGAAYRQWLSASDAVSAGAGSTAH"
     gene            55373..55804
                     /locus_tag="OPV72_000303"
     CDS             55373..55804
                     /locus_tag="OPV72_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCR9912712.1"
                     /translation="MNKPQSLRHALNKAVPYVRNNPDKLHLFVDNGSLVATGASSMSW
                     EYRYTLNVVIEDFSGDQNLLMAPVLLWLRDNQPDAINNPALREKLFTFDVDILRNDVC
                     DISLNLQLTERVLVSTDGSVSSVEAVAEPDEPEEMWTVKRG"
     gene            55797..56243
                     /locus_tag="OPV72_000304"
     CDS             55797..56243
                     /locus_tag="OPV72_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage virion morphogenesis protein"
                     /protein_id="HCR9912713.1"
                     /translation="MAELQKVDDWLSALLANLEPATRSRMMRQLAQELRRTQQQNIRM
                     QRNPDGSSYEPRRVTARSKKGRIKRQMFAKLRTTKYLKTAASADSASVQFEGKVQRIA
                     RVHHYGLRDRVSRKGPEVRYAERRLLGVNDDVEAMTRDMILQWLAG"
     gene            56312..56890
                     /locus_tag="OPV72_000305"
     CDS             56312..56890
                     /locus_tag="OPV72_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate assembly protein V"
                     /protein_id="HCR9912714.1"
                     /translation="MNAQLTEIMRLITNLIRTGVVTEVDREHWLCRVKTGDLETNWIN
                     WLTLRAGNARTWWKPSEGEQVVLLSLGGNLETAFALPAVYSNQFAPPSTSADACVTEH
                     PDGGWFEYEPATGRWYVRGIKSMVIEAADNITMKTSEFVLEADRTRINSEVVINGGVT
                     QGGGAMSSNGIVVDAHQHTGVLKGGDTTGGPV"
     gene            56887..57246
                     /locus_tag="OPV72_000306"
     CDS             56887..57246
                     /locus_tag="OPV72_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013098787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPW/gp25 family protein"
                     /protein_id="HCR9912715.1"
                     /translation="MTLYSGMNNTSGKVITDIDHLRQSVRDILLTPQGSRIARREYGS
                     LLSSLIDQPQNPALRLQVMSAVYVALSRWEPRLTLDSITINSHFDGSMVVELTGRRNN
                     GVPVSLSVSTGAENGSD"
     gene            57233..>57699
                     /locus_tag="OPV72_000307"
     CDS             57233..>57699
                     /locus_tag="OPV72_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HCR9912716.1"
                     /translation="MAVIDLSQLPAPQIVDVPDFDTLLAERKAEFVALHPKDEQEAVS
                     RTLELESEPVTKLLQENAYRELLLRQRINEAAQAVMAAYAIGSDLDQLAANYNVKRLT
                     VTPADNDAVPPVAAVMESDEALRLRVPAAFEGLSVAGPTAAYEFHARSADGRVA"
BASE COUNT        14056 a        15296 c        14905 g        13442 t
ORIGIN      
        1 ttagcgtgtc gcccggcgga gacagaacag gatgcttttt ataaagtgat tataaatcaa
       61 tagattattc gtcaccgaat agcgacaaat gaagtctggg atatcgccaa taaaccataa
      121 tggcaacacg tgcgggataa ggggttgaaa atgaacagaa aacaaaaaac cccgccgaag
      181 cggggctcaa aattggtcgg cgagagagga ttcgaacctc cgacccactg gtcccaaacc
      241 agttgcgcta ccaagctgcg ctactcgccg atatactgct tttttgaatt tttagttcaa
      301 ttcattgagt cgtggtgcga ggggggggac ttgaaccccc acgtccgtaa ggacactaac
      361 acctgaagct agcgcgtcta ccaattccgc caccttcgcg tttcacaact ctatattaat
      421 ggggtggcta atgggattcg aacccacgac aactggaatc acaatccagg gctctaccaa
      481 ctgagctata gccaccactg aaacttttta cgcggtatta aaccaccgca gctcaagcac
      541 ctaaataaat ggtacgcccg acaggattcg aacctgagac ctctgcctcc ggagggcagc
      601 gctctatcca gctgagctac gggcgcttag cgccgttgcg ggggtggata atacggactt
      661 cacaccccgc tgtccagtgc ctttttaaat aaaatgcgcg tttggttatg ctttgcgcat
      721 tttggcgctt attcccccac cttgtgggcg gttccgtgac gattcaggcc gaaaactttg
      781 tagaccagcg tgacggccag caggaagatg acgccgacaa acagcgacat gcgcgtatct
      841 tcattaaagt acatgccgat taaaacgcaa accagaaacg ccatcgtcaa atagttcgcc
      901 cacggaaaca taatggaacg aaaaggatga tccgcaatcg cttctttatg cgcccgacga
      961 aagcgcagtt ggctaatcag aatgacaaac cacggcacca tccccggcag tacgctggcg
     1021 ctataaacgt aaacaaagac gcgctgcgga ttggggataa tgtagttcag gcaagaacct
     1081 accagcaaaa tcaaaataga gagcgccacg cccgcgaccg gcacgccgtg gcgagagacc
     1141 ttcgcaactg ccgccggcag ttgacggttt ttcgccagcg cgtaaagcat acgcccacag
     1201 ctatacattc cgctgttaca gccggagagc gccgccgtca gcacgacaaa gttgataatg
     1261 cctgccgcgg cggtgatgcc gattttcgcg aaggtgagca caaaggggct gccgttgctg
     1321 ccaatctcat tccacgggaa aatggtgacg atcacgaaaa tcgcgccaac ataaaaaatc
     1381 aggatacgcc acagcacttt acccaccgcg ctacgcaacg tcacctgcgg attcttcgct
     1441 tcaccggcgg taataccgat caactcaacc ccttgataag aggccaccac gatacataat
     1501 gcggtcagaa agcctttcca gccgccggca aaaaagccgc catgctcggt cagattacca
     1561 aagccaatcg cctggccgcc gttaccaaag ccgaagaaaa tcacccccag gccgatgatg
     1621 atcatcacaa taatcgtggt gactttgatc atcgcaaacc agaactcgat ttcaccatac
     1681 aggcgcaccg cagccagatt cgccaacgcg accagtccga cggcaatcag cgccggtatc
     1741 cactgcgcca tctccggaaa ccagaactgg acgtagaccc caatggcggt aatttccgag
     1801 atcccgaccg ccatccacat aaaccagtat gaccaggcgg taagatagcc aaaaaaagga
     1861 ctcatatacc ggtgggcgta cacggcaaag gagccggtaa caggttccag aaagagcatc
     1921 tcccccatcg aacgcatgat gaaaaagacg aacaatccgg cgatgatata cgccagcagc
     1981 actgacgggc ccgcccattt cagcgtactg gcggcgccca taaagagtcc gacgccgatg
     2041 gtgcccccga gggcaatcaa ttcaatatga cgagcttcca gcccacgctg tagctccggt
     2101 tttttctctg ccataaatcc tcatgtcgtg tttgcaacgg ttccggtagt accggttatt
     2161 gttatgggta catcgattgt tgcgaatatt ttcttaaatt tggacaaatg gcaaatgaag
     2221 cattaaaaaa atgcgcttat tgtgtaagaa agcatcgatt atgttgtaaa tgagcagagc
     2281 cataagcaca gtccgctgct caagtcatca gaagggagaa tcagagatcg ccagtatagt
     2341 gccagcgaag atagcgcagc agacgcatct ggcgggtaat acgcttcggt tgcgaaagca
     2401 gacgatacaa ccactccagc cccaggttct gccatatttt tggggcgcgt ttgacgtgac
     2461 cggtaaacac atcataggta ccgcccaccc ccatatatag cgcatgggga tgcacttccc
     2521 gacaatcgcg catgagtaat tcctgttttg gcgatcccat cgcgacggtg acaattttcg
     2581 cgccgctggc atggatacgc gcaaatagcg cctgacgctg ctccggcgta aagtaaccgt
     2641 cctggctacc cacaatattg acgttccact gcgtccgcag ttttgcttcc gtctgcgcca
     2701 gcacctcagg cttgccgccg acaaaaaata ccggcgtgcc ttctttcccc gcgcgcgcca
     2761 ttaacgcttc ccaaaggtcg gcgccagcca cgcgagaaac ctgcgcctgc ggaaattttt
     2821 tacgtattga acgcaccacg ctgatgccat cggcatattt aaattccgcc gctgctatca
     2881 acgcgcggac ttccggatta tcttccgccg tcagcagctt ttcggcgttg atcgccacca
     2941 acgtgccttg cttcagttga ccatcggcaa acagataatt cagcgcatgt gacatgtcgc
     3001 gccagccaat cagaggtaat ccacgcagcg agtaaagggg cgcagcggca ttattggtca
     3061 tagttttcca tccatctgtg cctgagggag cgaagttgta cgtttatgaa tcagtccggc
     3121 gctatcaaat aaccagaaca gaagtttagc gaccagcagg ctggcgccaa aaaccaccag
     3181 gaagaaaacc acgcgcgaaa caaacgaatc cagcccttct cgcgccagca caatcatatt
     3241 aaagatggcg ccaaagcaga aactgtgcag aatcgccgcc ttatagcgat tgggttcccg
     3301 gttacccagt tcatacagcc agtcgaacca tttgataatc agcccgacga cgatcgcgcc
     3361 gagcggaata aacagtgccc cgcccatgac caccagcgat ccgataagcg ttggcgatat
     3421 cgccaggcca gaatggttgt tcaggacttc ccaggtgaag taattcgcag aattcagcac
     3481 gatactgggt cgtcccggcc ataaccaggt aggaataaag acgtagaaat cacgcacgat
     3541 aggggccagc ccctgaaaat cgatattgtg gtaattttgc aacagcagcg ccagattctc
     3601 ccacggcgaa aaggtatcgc gcgtcagata aagaaacgta tagaacgcct catcgccgct
     3661 cacatttaat ccgtagcgtt tgagcgccag ccagaacata ccgacaatcc ccagcacgcc
     3721 cgccgctgcc agcatccaca ggctgatcca gccccgaata atgccgataa acaggaagat
     3781 agcaaacgca ataatgatgt tggcgcgcgt gccgccgaca atcatgtagg tcaacagacc
     3841 aaacgcgacg gtgctcacca gaaagaacag ccacgctttg ctgtcctggc gcaggaaata
     3901 gaccaccagc atcgccggaa tgaagaaata gaagaaccgt tttaacgcca cgccggaaac
     3961 ttcgctggaa aagatctggc tgtaggagtg tagtcggaac agcaaaaagc cgttatgcat
     4021 aaagaaaatc gccacgctca ccagcgcgat gcccatcagg atcacccagg taaggtgggt
     4081 ttccacccgg ttcatggtaa atagcggctt gcgtggtaca tccacaacgc gtttgcgtaa
     4141 acgcgtttta taggtcacgt aatacacgcc gtagaaacag gcggcggata atagagcctg
     4201 caataagatt tccggcggcg cgacgccaac gtcgaaacga aataccagca cgctggttag
     4261 cggaaaacca aaaaagaagg tcaacaaaaa aagcaacgaa aagaaaacgt tgaagttaaa
     4321 acgcacgcgg cggaattcaa accaagtcag cgtggcgata aacagcgtag agagcagcca
     4381 gaccaccagc agcccgctga attgcattaa actcattcgg cttctcctgc ggcgattctc
     4441 aacgcattat gccacggttg caggtagttg gggctaaaga aggtgatgcc gcttttatct
     4501 accgatgcga gctgacgctg cgcctcgcgc acgacctgct cattaagatc gtccgtggta
     4561 aacaggacgg gcagatgctg ttccgccata tcctgccaga aaggattgtc gcgattcaac
     4621 acgcacggga tatcggcctg aattagcaga cacaacgtcc cgatcccctg ttggcgggca
     4681 aaaataaaat aaccgaggtc gcactggcgc aacagcgcaa gataggcatc aaattccatt
     4741 ttttcgctaa gaatttgtag attttcggcg ctaaatagcg ccagaccggc ctgacgaacc
     4801 tcatcaatat aggcctggtt attggctgga tagcccatcg gcaccaccac gtttaccgtg
     4861 tcgccaaact gctgatacac cgcccgtaac gccgcaatat gttggttact gcgatcgccg
     4921 gagttcccta ccaaaatggt caatttcccc gcacgttggc gctcttttgc catagcattc
     4981 agagaaggat ccatgcgcgt cgggaaatag agcaactcgc cgcgtacgcc cgggtgctgg
     5041 cgcgcaaaat agctgagatc gccgcgcgtc gcgaatacgc cccctactcg cccctgcgcg
     5101 atacgacgaa gcgggtagaa aaggcggaat ttcagcccgt tggacacttc gtagagatcc
     5161 gcgccccaga tatgccagta aaactgggct ggcttaatac cgccgcttaa cagcgccagc
     5221 cacagactga tgttgaactg cccgtgaaag aagaatctct gtcgacgatt tgctttcgct
     5281 ttggcgataa ccgcctgcgc cagcgctttc ttactgccat aaaaacgaag cgagagtgcc
     5341 ggacagcttt ccgtgaagcc gttatcttca ccggcaacca taaattcgcg cgcgtgctcg
     5401 cctgtggcgg ccagcgtatc attgaaaaac cgcagcacgg tgtggttatg gtgagggata
     5461 tccgatccca ggacgtgaat cagtacagtc atgctcgcct acgccagagt aaaaatacgc
     5521 cgcaacaaag tgaaaaatag acaatatagg tggccatata agcctgtgcc gcacccagcg
     5581 cgccgtgagc gggaatcagc cagtgagcga acgccgttaa cagaatgaac tggctaattt
     5641 cggccagaat gtaaaatcgc aacgacgctt tggcaatcac cagataaccg aaaacatagg
     5701 cgccgacttt cagcacgtcg cccactaact gccaagcgaa cagatcgcgc atcgcggtga
     5761 atttggcgga aaaaagcagc cagatagcaa aatcgcgcaa tagccagacg gtaaaactcg
     5821 ccgccgcaac cgccggtaaa acaaatttca gcgcttttac cacttcacgc gtaatgtcct
     5881 gtttttccgt caggcgtgag agcgtaggta acaggtaaac gctgaaggag gcggtgataa
     5941 attgtagata ggcatcagaa atactgctca cgccctgcca gatcccgaca tcgctccagc
     6001 tatagtgcgc ggccagttgg tttcgcatca tcacataggc gaccggcatc gtaacagagg
     6061 taatcagcgc catcagggta aatttactga gttgccctgc cagaccgttg tcccaggagg
     6121 gcttgagata gcgtagcggg acggtgccgc gcttaatcag tattataccg gctggcacta
     6181 ccaccagcgc cggcaccagc gccaggccaa gcagagcgcc ttcatagccg ccgacacggt
     6241 agcagagata ccaggcggcg acgcccaaaa agctgccgac aattaacgat aaggcattac
     6301 ccgacgcgtc acgaaagccc ttcattagcg ccagcagcag gttcgcccag gcgatcccca
     6361 tttgtaccag cgcaaccaga cgcaccagcc cttgatagtc cgtatgaccg aacagtccct
     6421 ggctaatcgg cgccgccgcc agcaggaaga ccagcgccag cagcgtagag aaccccaata
     6481 ccatcgcgga ggaggttccc accacggtac gtaactgcgc cgggtcatca tgatgttgtg
     6541 cgacgagttt ggtaacgccg ttaaatatcc cggcgccagc caatacgccc agcacggtaa
     6601 tcatctggcg gaagttaccc gcttgtccga cgcccgacgg accgaaagag acggccagta
     6661 gtttcaccac cagcagtccg gcgccaattt ttaccagcgt actgaccgcc gtccacaggg
     6721 aggctttagc aagcgacata tcaggagaaa taatttagca aggtagtaat caccgttcgt
     6781 tgatcgacgg gcgcaaggtt ataaaacagc ggcagacgca acaaacgttc gctctctttt
     6841 gtggtgtaga catcgtcccc gataaactcg ccgaatttat cgcccgccgg gcaatcatgt
     6901 agcggaatgt aatggaatac cgccatgatt tccgcctctt tcaggaaatt aatcagcgcg
     6961 ctgcgatcgg cgatatcccg cagtttgatg taaaacatgt gggcattatg cccgcagttt
     7021 tccggaatag aaggcagctc aatacgcccg gcgcgcgcca gcggcgttaa cgcatcgtag
     7081 taagtctgcc acagcgacag acgctgttga ttgatacgat cggcggcctc cagttgcgcc
     7141 cacaggtagg cagcctgcag atcggacatc aagtaactgg agccgatatc ccgccaggtg
     7201 tatttgtcca cctgaccacg gaagaactgg ctacggttgg tgcctttttc gcggatgatc
     7261 tccgcgcgtt caatcagcgt acgatcgttg atcagcgtcg cgccgccttc gccgccagcg
     7321 gtgtaatttt tggtttcatg gaagctaaaa cagccgatgt gaccgatcgt ccctaacgcg
     7381 cgccctttgt acgtggacat tacgccctgg gcggcgtcct cgacaacgaa cagattatac
     7441 ttatccgcca gcgccatgat gacgtccatt tcacaagcga cgccagcgta gtgtaccggc
     7501 acgatagcgc gggttttatc agtaatcgcc gcctcaatca gcgtttcgtc aatattcatc
     7561 gtatccggac gaatatcgac aaacacaatt ttcgcgccgc gcaggacaaa agcgttagca
     7621 gtggagacaa acgtaaagct cggcatgatc acttcatcgc cgggctgaat atccaacaac
     7681 agggccgcca tctccaaaga cgcggtacag gaaggcgtca gcaacacctt cgcgctgccg
     7741 aaatgttgct ccagccactg ctggcaacga cgcgtaaagc cgccgtcgcc gcacagtttg
     7801 ccgctgctca ttgcagactg catgtattcg agttcggttc ccaccaccgg cggcgcatta
     7861 aaaggaatca tgttgtcacc tgtataacca gtacgcagtg ctttcgatgt tggcaccgct
     7921 ttgtatgtaa cgtttaagcg cggcggtgtt gcccaactgg gtcgccaccc gcaatgttgc
     7981 tttgccgcga ctctgcgccc aacagatcgc cgcctgcata agttccgctc ccgcgccgcg
     8041 tccggccaac aggccaatgc gcacgtcggt atcattcaat tcccgcagcg agacgtaacc
     8101 acggatagcg cctgtctccg tgcgaagcac caggcattgg tgatcaaacg tgccgcgtac
     8161 cgcattctca atccactggg cgtaaaaacg ggcgctggcg tcgggcgcat accacggcgc
     8221 gcgaaaacga ctctgcgtaa acgcctctcc ggccaactga cgcaaagcag gaatgtccgt
     8281 aagatgtgca atttccgcgc catgctggtc gcgatgccct tttaccggca acgcaaaatc
     8341 cacctcgcct tcaaccaaag agaatcccag cgattgcaac gccgacagcc aggcgatgtt
     8401 ttcagccggc acttttgcct gcacgcgttg ccatgcctgc agcgcttctg gcgttaattc
     8461 gggcgctgag gcatcgatac gcacaatgcc gctattcacg ccaaagaacg tattttccca
     8521 gtgtaacggt tcaatactgg cgcggacggg cacggagcaa ctccagtaaa tattggccat
     8581 agccggtttt ttcaagctga ctggcggcgc gtttcaaacc atcatcatcc agccagccgt
     8641 tgcgccaggc aatctcctcc agacaggcaa ttttgaagcc ctggcgcttt tccaccgtct
     8701 gcacaaaagt gctcgcctca atcagactgt cgtgggtgcc cgtatccaac caggcgaagc
     8761 cgcggcccag cagttcaacg gtcagcttac cttcctccag atacatctgg ttgatagaag
     8821 tgatctccag ctcgccacgc ccggacggtt tcacgcgctt cgcatactcg acgaccttgc
     8881 tgtcatagaa atagaggccg gtgaccgccc agttagattt aggctgtttc ggcttttctt
     8941 ccagcgagag cgcgcgaaaa tcatcgtcaa actccacgac gccaaagcgt tccgggtcca
     9001 tgacctgata gccaaatact gtggcgcctt cggtacgcgc cgcgacctga cggagtttgg
     9061 ggctaaagcc ctgaccaaaa aagatattgt cgcccaatac taggcatgag ggttcaccgt
     9121 tgaggaacgt ttcgccaatg ataaaggcct gcgccagccc gtccggactg ggctgctcgg
     9181 cataatgtaa atcgataccg aatgctgcgc cgtcgcccaa caaacgctga aagtcgcgtt
     9241 tatcctccgg cgtggtgatg atcaagatct cacgaatgcc cgccagcatt agcaccgata
     9301 acggatagta aatcatcggt ttatcgtaga cgggcagaag ctgctttgat acgccgcgcg
     9361 taatgggatg caaccgggta ccggaacctc ccgccagaat gatgcctttc attcgtttct
     9421 cctccaggag taagagcctg ccgtttagcg tttcagacct aagcgttcgc cctgataact
     9481 gccatcctgc acgggtttcc accaggcctc attggcgaga taccactgaa cggtttttcg
     9541 catcccgctt tcgaaggttt cctgcggcgt ccagcccagc tcgcgggcga ttttcgacgc
     9601 gtcgatggca taacgtaagt catggccggg tcgatcgtcg acgaaggtaa tcagatcgtg
     9661 ataattcgcc acaccctgcg gtttttgcgg ggccagttcc tccaacagag cgcagatcgt
     9721 cctgaccaca tccagatttt tacgttcgtt atgaccgccg atattatacg tttcgcccac
     9781 cgcaccgttc gtcaccacgt gatacaacgc acgggcatga tcctccacat acagccagtc
     9841 gcgaatttgc tgaccgttgc catagaccgg caatggttta cccgccagcg cgttcagaat
     9901 catcagcggg atcagttttt ccgggaaatg gtagggcccg tagttattag agcagttggt
     9961 gacaagcgta ggcagaccgt aggtacgtaa ccaggcgcgt accagatggt cgctgctggc
    10021 tttggaggcg gaataagggc tgcttggcgc atatggcgtg gtttcggtga agaaatcgtc
    10081 tgcagtatgc agatcgccat acacttcatc ggtggagata tggtggaagc ggaacgccgc
    10141 tttagcgtcc gcgtcaagcg cggaccagta agcgcgagcg gcttccagca aggtgtaagt
    10201 accaacgata ttcgtttcaa taaacgccgc cgggccgtcg atggaacggt ctacatggct
    10261 ttccgccgcc aggtgcatca cgctatcggg ctgatactgc tggaaaactt gctccagtga
    10321 tgcccgatcg cagatatcca ccttctcaaa ggcgaaacgg tcgctttgcg ccaccgacgc
    10381 cagagacatc aggttgcccg cataggtgag tttatccacc accaccaccg cgtctgccgt
    10441 ttcatggatg atatgccgca ccaccgcaga tccgataaag cctgcgccgc cggtcaccag
    10501 aatgcgtttc atcagcgcca gacccctttg gtatcaacca cataacgttg atgaaccgca
    10561 tcgccgggaa tcgctttaaa ttcgtcgtga tcgaccagca tcaccagcac atcggcggcg
    10621 gccagcgccg cgtccagttt cgccagcgtg caaagtccgt ccaatttttt cggcaactga
    10681 cggatattcg gttcgacgac cagggtttcg ccgctgtgcc agcgggcgat actttgcgcg
    10741 atccccatcg ccgggctttc gcgcagatcg tcgatattcg gcttaaaggc cagcccaaaa
    10801 caggcgattt tcacttcgct ggcgcgttta tcggtggctg ccaggcaatc tgcgaccgcg
    10861 gcttttacct gatcgaccac ccagtgcggt ttgccgtcat tcacttcacg cgcggtgcga
    10921 atcagtctcg cctgctgcgg attttgcgcc acaataaacc acggatcgac cgcaatgcag
    10981 tgcccgccaa cgcctgggcc cggctgcaaa atattgacgc gcggatggcg gttcgccagg
    11041 cggatcaatt cccagacgtt aatcccctgt tcggcgcaaa tcagcgacaa ttcattcgca
    11101 aaggcgatat tcacatcacg gaagctattt tccgtcagct tgcacatctc tgcggtgcgc
    11161 gagttggtga caacgcattc gccctcaagg aaaattttgt acagcgcgct ggcgcgagcc
    11221 gaacatactg gcgtcatacc gccaatcacg cggtcatttt taatgagttc caccatcacc
    11281 tgacccggca gcacacgctc cggacaatag gcgatattca cgtcggcctg ctcgcccgcc
    11341 tgctggggaa aggtcagatc cgggcgcatc ccggccagcc agccagccat ttgctccgtt
    11401 gcgccgaccg gcgatgttga ttccagaatc accagtgccc ctttttttaa taccggcgca
    11461 atggatttcg ccgcggcttc cacataggcc atgtcagggt cgtgatcgcc tttgaatggc
    11521 gtcggcacgg caatcaggta cgcatcggcc tcgacaggtg tcgtcgtcgc acgcagaaag
    11581 ccgccttcca ccgccatctt caccacattg cccaacgccg gctccacgat gtgaatttca
    11641 ccgcgattta tggtgtctac agcatgttgg ttgatatcca cgccgataac ctgcttctgg
    11701 cgggaagcaa aagcggccgc agtcggtaat ccgatatacc ccagcccaat aacagaaatg
    11761 gtcgtaaaac tcataacgat acccgataac tttttaacgc ctgtaaaatg cgcgcgcatg
    11821 attgcccgtc accataagga ttatgggcgc ggctcatggt ttgatattca ttttcgtcgt
    11881 gcagcagacg cataacttcc gccacaatgc gccgggagtc cgtgccgatc agtcttaccg
    11941 taccagcggt aatggcttcc ggacgctctg tggtttcacg catgaccaat accggcttac
    12001 ctaatgacgg cgcttcttcc tgaataccgc cggaatcggt cagaatgagc caggcgtgat
    12061 tcatcagcca gacaaaaggt aagtagtcct gcggctcaat cagtaccacg ttttcaacat
    12121 ggccgaggat acggttgaca ggttcgctga cgttgggatt gagatgcacc ggatagacaa
    12181 tttgcacatt ctggttcgcg gcggcaattt ccgccagcgc ctggcagata tgctcaaagc
    12241 cctgaccaaa gctttcacgc cgatgaccgg tcaccaaaat catcttctta ttcgcgttga
    12301 ggaaaggata ctgctcggcc agttcagcct gtaatgtatc gctcgtcaga acgcgatcgc
    12361 gtacccagat cagcgcgtca ataacggtat tgccagtgac aaaaatgcgc tcatccggaa
    12421 tgttctcccg caacagattc tgccgcgagt tttccgtcgg cgcaaagtgg tacatcgcca
    12481 gatgtccggt cagcgtgcgg tttgcctctt ccggccaggg ggaatagaga tcgccggttc
    12541 gcaacccggc ttctacgtgc cctaccggaa ttcgttgata gaaagccgcc aggctggtag
    12601 caatcgtagt ggtggtatct ccatgaacca gcaccacatc aggtttaaaa tctgccagga
    12661 tcggctttaa tctctccaga attcggcagg taatttccgt caacccctgt cccggctgca
    12721 taatgttgag atcgtaatca ggcacaatag aaaaaagagt taatacctga tcaagcatct
    12781 cccgatgctg cgcagtaacg catactttgg cctcgaaatg aggatctttt tccagcgcat
    12841 ggaccagagg cgccatctta atggcctccg gtcgtgtacc aaatacagtc agtactttca
    12901 catcgattct cttcgaatag acagtagggg cccagccccc tactgcagag gtgttgctaa
    12961 atcgtgcggc gacgggttaa ggcaacgccc gcaccgatta gcgccccaac gataccccac
    13021 ataatcatca ggaaggctcg gcgtgggcta tcacgtttta ccggttcttc cggcgtacgc
    13081 aaataacgat aggtctgaaa acgagggtcc agggtcggcc ccacattaag cgtattcaac
    13141 attgcccgat tttgaaagta gtccaaatcg aacgcagggc caaccgcttg cagattttca
    13201 agacgcgcct gcaacatagg gcgaccgagt aaaaaaagct ctgagtccgg taattcatcc
    13261 gccgggacat ctgtcgcgct acgagaaata ttatgttgtt ccgcaatttt gagcgcctgc
    13321 tcaatactgt ttacacgacg cgaatagatc gctttcgcaa cctcttcctg ccgtttgacc
    13381 tgggctttca tctgcacggt acgcgcagcc caggcacctt ttaattcatc attcagatgg
    13441 ctcgccgccc gctggctggc gaatgcgaca tactgacgca gcagattatt ggcatccggc
    13501 gcagtttcag caatcagcct cacgttgtcg ttgatggcgc gtgtaaaatc gccgggcgta
    13561 aactgtatgt tattgatcag ttcatcaagc atcaccgcat cagctttgct attcccgacc
    13621 attcgctgct tgtaatagtc cgtctgtaac cagaaatcgc gacgcgtatc ccaggaggca
    13681 agttgcatga tgaactcttt atacgcttca tccatcaccg agggcttatc agaagaagca
    13741 ggatcggtct taatatccag gttgcgcaga aactgctgct gggagtaata accgcccaac
    13801 atatttacgg ttgggcgatc ggtgatcgcc gtcgcactcc actcctgacg agcaaaaaag
    13861 gtataggcta acgcgataag ggcaaatagc aggccaatgc cgataatcca gaatttgcca
    13921 gcccataaag tacgaaacaa cccgcgaata tccagttcat tttcagcgct caccgcgcgt
    13981 gcccccggta atggttgtgt catcgtatcc tcatttactt ggttaagttt ggccggttct
    14041 tacgttgcct gcgcaggcga cgcttcacac gcttaataaa tctcgccacc ttccaggccc
    14101 gcttaatgca gtagccatag aggaagaatg ctagcaaaaa gagcaccaac ataacccatt
    14161 caggaacaaa atgagagtat tctgccgtta cgcctactcc cgccagaatc gccgctgcga
    14221 gcgtaataag aacaaatgcc tggcgggaag taaaccctgc tcgcataacc aaatgatgaa
    14281 tatgttggcg atcaggggaa aaggggctca tccctttacg cagacggcga tacataatcg
    14341 ccaccatatc catcaatgga atagcgataa tccatagcgc ggtaaccggg ctgatagagt
    14401 gagttttccc ctgcgtcgtt tccagtaaga gccagatgac ggtaaagcca atcagtgtac
    14461 taccggcatc acccataaag actttataac gccgccccaa aataccgaga ttaagcataa
    14521 tgtaaggcag aatcgcggcg atcatggcaa agcaccacat tgccagacta gtctgaccat
    14581 caaaccataa aatcagcccc atcgccgcaa atgagacgct ggataaccca cccagcagtc
    14641 cgtcaatacc gtccaccata ttgaaagcgt tgatcgccgc ccatacggca aacagagtaa
    14701 ggaaatagcc aaaggggcca agcactaact cccaaggccc aaagatgtaa ccaaggctac
    14761 ctaagtgaag ttttgcgata accatcatta caaccgcaat aacagcctga accacagcac
    14821 gaatttttac actgatatca aaacggtcat ccatcgcacc aacaaaaacc aatacaccag
    14881 cgcaaataag atatagcgat aagtgcggta tgtagtaatc cgagaggcca aacataaagc
    14941 agattcctgc aaacacagaa atcccgccga ctaatgggat aacgccctga tgtcgtttac
    15001 gaaagtttgg tttatccact aaaccaattt ttatggctac ttttcgcgca agaaaaataa
    15061 aaatggtcgt gaataaaaaa atactgatta gctcagataa agcggtgagt aacttcacag
    15121 tgtatgtgct ctcagcatat atcatttcct taaagtataa tgcgttacgc cagctcctag
    15181 aagagacctg ttagaacatt acacttttta ccgcaaacaa tgtgtattgt gcatggtgtt
    15241 actctgtagc gcatatcccg atgaccagtt tatatgacat gacgccagga tgaatcgcaa
    15301 aacaaaaacg ccacgtaaaa acgtggcgtt ttcaggtaaa gaccaggtta tgagcgcttc
    15361 atcatctcga aaaagtcgtc attagttttg gtcatcgcca gtttgttaat gaggaattcc
    15421 atcgcgtcaa tctcacccat cggatggatg attttacgca ggatccacat tttctgcagc
    15481 tcttcctgag tggtgagcag ctcttcttta cgggtaccgg aacggttgta gtcgatagcc
    15541 gggaagacac gtttttcagc gatcttacgc gagagatgca gctccatgtt accggtgcct
    15601 ttaaactctt cgtagataac ttcgtccatc ttggaaccgg tatcgattag cgccgtcgcg
    15661 atgatagtca ggctaccgcc ctcttccacg ttacgcgccg cgccgaagaa gcgcttcgga
    15721 cgatgcaggg cgttagcatc cacaccaccg gtcagtactt taccggaagc cggcaccacg
    15781 gtgttgtagg cacgcgccag acgggtgatg gagtcgagca ggatgatgac gtctttcttg
    15841 tgttcaacca gacgtttcgc cttctcgata accatttcgg caacctgaac gtggcgggat
    15901 gccggttcgt caaaggtaga ggcaaccact tcgcctttca ccagacgctg catctcggtt
    15961 acttcttccg gacgttcgtc aatcagcagc accatcagca cgcagtctgg gtggttatac
    16021 gcgatgctct gcgcgatgtt ctgcagcagc atggttttac ccgccttcgg cggcgcgaca
    16081 atcagaccgc gctggccgcg accgatcggc gaagccagat ccagaacgcg cgccgttaag
    16141 tcttcggtag aaccgttacc acgctccata cgcagacgag agtttgcgtg cagcggggtt
    16201 aagttctcaa agaggatttt gttacgggcg ttttccggtt tgtcgtagtt aacttcgtta
    16261 actttcaaca gcgcaaaata gcgttcacct tctttcggcg ggcgaatctt accagaaatg
    16321 gtatcaccag tgcggaggtt gaaacggcgg atttggctgg gggaaacgta gatatcatca
    16381 ggaccggcga ggtaggagct gtctgcagaa cggaggaaac caaatccatc ctgcaatatc
    16441 tccagcacac cgtcgccaaa gatatcttcg ccactctttg cgtgctgctt caggatggca
    16501 aaaataatgt cctgcttgcg catacgggcc aggttttcca gccccatact ttcgccgaga
    16561 gtgatcagct cagaaaccgg cgtattcttt aattcggtaa gattcataat ggtgtgagtt
    16621 cttaaacttg gggtaaatct cgaacttaat gttgtgaatg gtatggcagg gtcatccatg
    16681 cctgtttacg gctatcaact catgtctgtt cgctgtctgg tcacaggaaa gtacgcagaa
    16741 ctgaaacgac aagacggaat gagcgaagag ccaggaatct ttccacttct cgtgcgagaa
    16801 aaaacgggaa gtgacggata aaaccagatt caaacttaat aaggtatgtt taattcgaag
    16861 tcaatactaa cttagcacga ctcagaccgg gcgtccagag atcctgacaa tttaagaata
    16921 acgtaaggac aacagacgcc acgaaactgc ctgatacctt aatcattcgt cgaatgacag
    16981 acgcctgacc atacagcgcc tttgtcattc gacgtataaa aggtattacg ccagattggc
    17041 gtcgagaaac tctttcaact gacctttaga caatgcgcct actttggttg ccgccacttc
    17101 gccgttttta aacagcagca gagtcggaat accgcggatg ccatatttag gcgcagtacc
    17161 tgggttctgg tcaatgttca gtttggcaac ggtcaatttg ccctgatatt cgtcagcgat
    17221 ttcatccaga atcggagcga tcattttaca cggcccgcac cactctgccc agaaatcaac
    17281 gaggatagcc ccgtccgctt tgagtacatc cgtgtcaaaa ctgtcgtcag tcaggtgaat
    17341 aattttatcg ctcatatata actccacagg aataagcctg gcgtgttggt gtagcattaa
    17401 ccaacgaggt gctgatgtta acttcgccaa caaaggttga ctttatttca ccggatacgc
    17461 tttcgtaaag caatagtaag ctgatattct accacactat gagcaaaaca catttaacag
    17521 aacagaagtt ttccgacttc gccctgcacc cacaggtggt tgaagccctt gaaaaaaaag
    17581 ggttttataa ttgtacgccc attcaggcac tggcccttcc gctaacgctg gcgggtcgtg
    17641 acgttgcagg gcaggcgcaa accggtaccg ggaaaacgat ggcgtttctg acgtcaacgt
    17701 ttcattattt actttctcat cccgcgatcg acgatcgcaa ggtgaaccag ccgcgcgcgc
    17761 tgatcatggc gccgacgcgt gaattagccg tacaaattca cgcagacgcg gagccgctgg
    17821 cgcaagcgac aggcttaaaa ttaggcctgg cttacggcgg cgatggttac gacaagcagc
    17881 ttaaagtgct ggaaagcggc gttgatattc ttattggtac gacgggccga ttgatcgact
    17941 acgccaaaca aaaccacatt aacctcggcg ccattcaggt cgtcgtactc gatgaagccg
    18001 atcgcatgta cgatttgggc tttattaaag atatccgctg gctgttccgt cgtatgccgc
    18061 cggctgcgca gcgtctgaac atgttgttct ccgccaccct gtcttatcgg gttcgcgagc
    18121 tggcgtttga acagatgaac aacgccgaat atgttgaagt ggaaccggag caaaagaccg
    18181 gccaccgcat taaagaagag cttttctacc cctctaatga agagaaaatg cgtttactgc
    18241 aaacgctgat cgaagaagag tggccggatc gcgccattat tttcgccaac accaagcatc
    18301 gttgcgaaga tatctgggga catctggcgg cagatggcca tcgtgttggt ctgctgaccg
    18361 gcgacgtcgc gcagaaaaag cgcctgcgga ttctggatga gttcacccgc ggcgatctgg
    18421 atattcttgt ggcgaccgat gtcgcggcgc gcgggttgca tatccccgcc gtaacgcacg
    18481 tctttaacta cgatctgcca gacgattgtg aagactatgt tcaccgtatc ggtcgtaccg
    18541 gtcgcgctgg cgccagcgga cattccatca gcctggcttg tgaagagtat gcgctgaatc
    18601 tgcccgctat tgagagctat atcggccact cgattccggt cagcaaatac aatccggaag
    18661 cgctcatgaa cgatctgccc aagccgttgc gtctgacgcg ttcgcgtcct ggcaatggtc
    18721 cgcgccgcgc tggcgctccg cgtaatcgtc gtcgttcagg ttaagaaaag ttatgccata
    18781 cacaaaatca tttagcctgt atcaaggcgg caagaaaaca aatcccgatg agcttaggaa
    18841 gagtacgcag ccaacacgga tacaggttga aggatgaagt gtatgaattc cacctcgttg
    18901 tatgccgcca ttgatctcgg ttccaatagt tttcatatgc tggtcgtgcg cgaggcggcg
    18961 ggaagcatcc agacgctgac ccgaataaaa cgcaaggtgc gtctggccgc gggtctgaac
    19021 aacgacaacc acctttcagc cgaagcgatg gaacgcggct ggcaatgcct gcgtctgttt
    19081 gctgaacgtt tgcaggatat cccgcagcca caaatccgcg tggttgccac cgcaacattg
    19141 cgtctcgccg tcaatgcagg tgaatttatc gcgaaagcgc agactatcct tggttgtccg
    19201 gtgcaggtta tcagcggcga agaagaggcg cggctaattt atcagggggt cgctcatacc
    19261 accggcggcg cagatcagcg actggtggtg gatatcggcg gcgccagcac tgaactggtt
    19321 accggcactg gcgcgcaaac cacgtcgctg tttagcctgt cgatgggctg cgtaacgtgg
    19381 cttgaacgct attttagcga tcgtaatctg gcgcaagaaa actttgatga tgcggagaaa
    19441 gccgcgcgcg atgtactgcg tccggtcgcc gatgaactgc gttttcatgg ctggaaggtc
    19501 tgcgtgggtg cctccggcac cgtacaggca ttgcaggaaa tcatgatggc gcaggggatg
    19561 gacgagcgca ttacgctcgc caaactgcag cagctaaaac aacgcgcgat acagtgcggg
    19621 cgtctggaag agctggaaat cgaaggcctg acgctggagc gcgcgctggt tttcccaagc
    19681 gggctggcta ttctaatcgc gatatttacc gagctgaaca tccagagcat gacgctggca
    19741 ggcggcgcgt tacgcgaagg gctggtgtat gggatgttgc atctggcggt agatcaggat
    19801 atccgcagcc gcacgctgcg aaacattcag cgtcggttta tcgtcgatac cgatcaggca
    19861 aatcgtgtgg cgaagctggc agataacttc ctcaaacagg tagaaaatgc ctggcatatt
    19921 gaacctatca gtcgtgaact gttgcttagc gcttgccagt tgcatgagat cggtctgagc
    19981 gttgatttta aacaggcgcc ctatcatgcc gcctatttag tacgccattt ggatctgcct
    20041 ggctatacgc ccgcgcagaa aaagttgctc gccaccctct tactgaatca gaccaatccg
    20101 gtcgatctct cttcgcttca tcagcaaaac gcggtaccgc cccgtgttgc ggaacagcta
    20161 tgccgtttgc tgcgactggc gattcttttt gccggtcgcc gtcgtgacga tctggtacca
    20221 gaaattacgc tacaggcgct aaatgaaaat ctgacgttaa ccttgcctgg cgactggctg
    20281 gcgcatcacc cgctgggtaa agagttgatt gatcaggaaa gccagtggca aagctatgta
    20341 cactggccgc tggacgttcg ctaaccgtag tctgattgcc ggatgacgct tcgcttatcc
    20401 ggcctacgat ttcgctcgct ttgccgccat catggctttc agattagcca ggtgactttg
    20461 ccctttttgc attcgctcct cagcgcttac cactttgcgc tcctgctccc agattaaatc
    20521 atcctgcggc agttctaaca ggaagcgact gggttccggg cgcaccagtt ccccatactg
    20581 acggcgctct ttacataatg taaaggtgag ctctttctgc gcacgagtga tcccgacata
    20641 ggccagccga cgctcttcct caatattgtc ttcgtcaatg ctgctttgat gcggcaaaaa
    20701 tccttcttcc attcccacca tatagacata caggaattcc agtcctttcg acgcatgaag
    20761 cgtcatcaac tgtacctgat ccagctcttc ttcgctctcg ccgcgctcca tcatatcgcg
    20821 cagcgtaaag cgtgtaacca cctgggtgag cgtcatcggc tcatcgagtt cgttgccttc
    20881 cagcatctca gtcatccagc taaagagctg gttaacgttt ttcatacgca tttccgccgc
    20941 tttggggctc ggcgaggttt cgtacaacca ggattcatag tcaataccgt ggatgagatc
    21001 gcgcacggcg gcgacaggct cacgttcggc cagacgctgg atttccccca gccagtgggt
    21061 aaaacgcgtc aatgaatcgt aaccacgtcc ggtcagcttc tggctaagcc ccatatcaaa
    21121 gctggcggta aacaggcttt tattacgcgt cattgcccat tcacccagct tttgcagagt
    21181 ggccggaccg atttcgcgtt ttggcgtatt cacgatgcgc aggaaagcgc tgtcatcatc
    21241 cgggttggtc aacacccgca gataggccag caagtcttta atctccggac gggagaaaaa
    21301 tgaggtgccg ccggaaattt tgtacggaat gcggttctgc atgaggaatt tttcaaatac
    21361 ccgcgactga tgattcccgc gatacagaat ggcgtaatcc ttgtactggg tcttgttcac
    21421 aaagtgatgg gcaatcagtt cgccggtaac gcgctcagct tcatgctctt cattgtttgc
    21481 gcttaacact ttgagttccg cgccgtaacc gagttcggaa aagaggcgct tttcaaagac
    21541 gtgcggattg ttggcgatga gaatatttgc cgctttcagg atgcggcccg aagaacgata
    21601 gttttgctcc agcttaatca cctgcagcgc cggaaaatcc tggctcagta acaccaggtt
    21661 ttgcggacgc gccccgcgcc aggagtagat agactgatcg tcatcgccta cgaccgtaaa
    21721 gcgcgcgcgt tgcccaacca gcagcttaac caactcatac tggctggtgt tagtatcctg
    21781 atattcatcc accagcagat aacgaatttt attctgccag cgctcgcgca cctcgtcatt
    21841 gcgttgcagc agcagcgtcg gcagcaaaat caaatcatca aaatcgagaa cgttacatgc
    21901 cttcatatgg gcgtcgtaaa gcccgtagca gtgggcaaaa atacgatcgc gttcaccttt
    21961 cgcccccgcc gctgcctgtg caggcgtttt gagatcgttt ttccagttgg agatcgtgga
    22021 gatcagctgt tgcaacagaa ccttgtcgtc ttcgatcagg ccttcggtca gctctttgag
    22081 caaggcgacc tggtcggtat cgtcaaacaa tgaaaagttc gatttcatcc ccagcgcagc
    22141 gtactcgcgc ttaataatat ccagccctag cgtatgaaag gtggagatca tcaaaccgcg
    22201 cgcttcctta cggccgagcg tctgcccgac acgttctttc atctcacgcg ctgccttgtt
    22261 ggtaaacgtc accgccgcaa tatgccgggc ctgatagccg catccgcgga tcaggtgggc
    22321 gattttattg gtaattacgc gagttttacc agaacccgct cctgccagca ccaggcaggg
    22381 tccggtgacg aattcgacag cgtgttgttg gccaggattt aaacgcatgg gaatagtgct
    22441 caatcttcga acgggggagg gattgtagca gaaagcgagg cccagagaag accaggctgc
    22501 tttttcaggc agcctggaaa aggtcaatca gcaggctctg gcggcaagcg acgtatagcc
    22561 attacgctgt gcgctcttga tccaactgta agaacccatt agcgcgatca ccgtcagcag
    22621 aacatactca agcgacatcg cataaacgcc ctgtactgca tagatcacga cgctaattac
    22681 atcaataatc acccacagca gccagttttc cacgtacttg cgggtcatca gcaccatcgc
    22741 cgcaatcgac aacaccagca tggtggaatc ccagaacggg aacgcgtccg gctggagttc
    22801 aggcatcgcc acctgcatac ctaccgtttg cagcagagcg agcataacgc gggtcaacat
    22861 agcgaagacc ggatcgataa accacgtcat cagcagaatg ctaataatac atatgccccc
    22921 caacctccat gtttgttgac aagaaagcca gcgtactttc agagcggctt cccgggcgtc
    22981 attctgccgg ctccatgcgt accagccgta aatattcgcc gcaaagaaaa acacctgaag
    23041 tagcaagctg gcatacagtt gaatctgaaa aaagatggcg gcaaacagag tgacgttaat
    23101 caagccaaac aggtaattaa tgattttttc ccggctggcg caccagatgc acaataagcc
    23161 aaagacggta ccgatagcct caatccacga tagcgcatac ccaccctcgc cgagaggaat
    23221 gttgaccatt acattgttaa tgctgaaaaa gtccatcatt gctctccttg caaactatcg
    23281 aaataaatgg cctgaagcgc cagagaaatc tggcgctctt caccttgctg gcacaaggtt
    23341 tcctgctgaa cataatggtt aatgctgctc tccagacagc cactatgcgc gacgaccacg
    23401 tttagcaacg acgcggtacg cagcccacgt aacgctccca ccaccatcag cgcggcggtt
    23461 tccatatccg cgccgagaac tcccctggcc gaccattcgg catccagttc agcttcgcga
    23521 tcggtataaa aactgtcatg gctgcgcacc agcccgcaaa cggcagagat gttcatctgt
    23581 ttcgcctgct gtatcagcgt ggcggtaaga taagggtccg cacaggccgg ataactggcg
    23641 ggcgcatagg ttttgctggc gccgtcgtca gccaccgcgc cgtgggcgat gatcacatcg
    23701 cccaacgcca gcgagtcctg caacgcgccg caactaccga tacggattag cgtgttgacg
    23761 ccaacctggc gtaactcctc aatggcgata gcggttgacg gtccgccgat tcccgtggag
    23821 agcacgacta tttcaacccc ctggtaccag ccgcgcgccg cgcgaaactc ccggttttgc
    23881 cccagaatct cagccttatc aagaaaacgg gcgattctat ccacccgccc gggatcgccg
    23941 ggcaaaagcg catatttcgc gcgggtcatg cttgtgttaa gccgaatatg gggttgcatc
    24001 tccctctcct tattgttctg agaggttcag atttccgcct cctgtttgag tttttcagga
    24061 gccagtaaaa tgatccgctc accgtcggta tcgataatgt tcagcgattt cagatcgtgc
    24121 agtatccggt tgatactgcg cgtcgtcgcc gcaaattcct gaccaagatt ctgcttatca
    24181 agcaaaatag tggttgattc atattgttga taacgcagcc ataatgcctg gcatacgcgc
    24241 tgatgcagcg agtacaaatt gtcgctactg gcctttttcg acaactggta atactgttgg
    24301 ctgaaaaacc gcagcattcg ctggttaaag tggttatcca gcgtcagcca gcggcaaaaa
    24361 tgtgcttgcg gcaggctaag tagctgtaca ttgccgacgg ctacgacaga acagatgtaa
    24421 tgccgcgact caaatatctc tagctcgccc agcatgtctc ctttgccata acgcgcctgc
    24481 cggtaacggc gtccatcttc agcttcgtaa aaaacatcca cttcgccggc cacgatgagc
    24541 gaaaattgct agcatgtttc cccctggcgg cagataagcg cgccgcggga aatgtcgtca
    24601 aatcgccagc actgcatgat ttccaacggg cagtatttga gtaattcata gagcactggg
    24661 tcgcgtacga cctggcgtag ccctaaaagc cagtcgtctg gaaattctgc gtttttcatt
    24721 atgttcatgg tatctcgccc cttgtcagaa aggacaggac cgtcgtcccg cccatccgaa
    24781 atacgcccgc taaaaatgcc gcttatctcc cggttcatta aatcaggcgg gacatctgtc
    24841 ctgtaatggc gaagagtata tgtctgacgg cctaaggagt gataaagtga cggccaatct
    24901 ttgcgacgtg agaacacaat aatggcaaaa atggcagcag cactgcatat tcttgtaaaa
    24961 gaagagaaac tggctttaga tcttctggag caaattaaaa acggcggcga ttttgagaag
    25021 ctggcgaaga agcattctat ctgcccatcc ggtaaaaaag gcggtcattt aggcgaattt
    25081 cgtcagggcc agatggttcc ggcattcgat aaagtagtct tttcctgccc ggtactggag
    25141 ccaaccggcc cactgcatac ccagttcggt taccacatca ttaaggtatt gtatcgtaaa
    25201 taaaaagccg ggtggcggct acgccttacc cgacctacat cgtctgcttg attttgtcgg
    25261 tcgggtaagc gctagcgcca cccgacaagg tatatcaacc cgctaccgca atacgcttca
    25321 tatccgtcat atagccgcgc agtttcttac ctacctgctc aatcgcatga ctacgaatcg
    25381 cgtcgttcac gtcgcgaagc tgtgcgttgt ctaccgcgcc ttccgggata gcactaccca
    25441 gatcgcccgg ttgcaattcc gccataaacg gtttcagtag cggtacgcaa gcgtaagaga
    25501 acaggtagtt accgtattct gcggtatcgg agataaccac gttcatttcg tacaggcgct
    25561 tacgggcgat ggtgttggca atcagcggca actcgtgcag tgattcgtag taagcggatt
    25621 cttcgatgat gccggaatcg accatggttt cgaacgctag ctcaacgccc gctttcacca
    25681 tcgcgatcat cagaacgcct ttatcgaagt actcctgctc gccgatttta ccttcaaact
    25741 gcggcgcggt ttcgaacgcg gttttaccgg tctcttcacg ccaggtcagc agtttcttat
    25801 cgtcgttcgc ccagtcagcc atcatgccgg aagagaattc gccggagatg atgtcatcca
    25861 tgtgtttctg gaacagcggc gccataatct ctttcagctg ttcggacagc gcgtaagcac
    25921 gcagtttcgc cgggttagac agacggtcca tcatcagggt gatgccgccc tgcttcagcg
    25981 cttcggtgat ggtttcccag ccgaactgaa tcagtttttc ggcgtatgcc gggtcggtgc
    26041 cttctgccac cagcttgtcg aagcacagca gagaaccggc ctgcagcata ccgcacagaa
    26101 tggtctgctc gcccatcagg tcagatttca cttccgccac gaaagaagat tccagtacgc
    26161 ccgcacggtg accgccggtg gccgcagccc aggctttagc aatcgccata ccttcgcctt
    26221 tcggatcgtt ttccgggtga acggcgatca gcgttggcac accgaagcca cgcttgtatt
    26281 cttcacgtac ttcggtgccc ggacacttcg gtgccaccat caccacggtg atgtctttac
    26341 ggatctgctc gcccacttcg acgatgttga agccgtggga gtaacccagc gctgcgccgt
    26401 ctttcatcag cggctgtaca gaacgtacaa cgtcggagtg ctgtttgtcc ggcgtaaggt
    26461 taaccaccag gtcagcctgc gggatcagct cttcgtaggt gcctactttg aagccgtttt
    26521 cggtcgcttt acgccaggag gcgcgcttct cagcaatagc ttctttacgc agggcgtagg
    26581 aaatatccag accggagtca cgcatgttca ggccctggtt cagaccctga gcgccacagc
    26641 cgacgatgac cactttttta ccctgcaggt agctcgcgcc gtcggcgaat tcgtcgcggc
    26701 ccataaagcg acatttaccc agctgcgcca gctgctggcg cagattcagt gtattaaagt
    26761 agttagccat gatggtgtac tccgtgatgt tgtgttgtcg cgcttattgt tcggtttaca
    26821 gattgctatc tgtgcgaatg aacccacatt acaacaggaa atttattgcg gaaattgata
    26881 tattcacaac gttatgttgc ggtttatgca acgtcaaaaa ccggaggtct gtctgtggat
    26941 ttacgcgatc taaaaacctt cctgcatctg gcggaaagcc gccattttgg ccgcagcgcg
    27001 cgggcgatgc atgtcagtcc ttccaccctt tcccgacaga ttcagcggct ggaagaagac
    27061 ctcggccagc cgctgtttgt gcgcgataac cgtacggtca cgctgaccga agcgggtgaa
    27121 gagctgcgag tgtttgccca acagacgctt ttgcaatatc agcagttgcg ccataccctc
    27181 gatcagcagg ggccgtccct ttccggcgaa ctccatatct tctgttcagt gactgcggcg
    27241 tacagccacc tgccgccgat tctcgaccgt tttcgcgccg aacacccttc tgttgaaatc
    27301 aaattgacga ccggagacgc cgccgatgcg atggaaaagg tggtaacggg agaagcggac
    27361 ctggcaatcg ccggcaaacc agaaacgctg cccggcgcgg tggcgttttc gatgctggaa
    27421 aatctggcgg tggtgctgat cgccccggcg ctgccctgcc cggtgcgtaa tcaggtgtcg
    27481 gttgataagc ccgactggtc aacggtgccg tttatcatgg ccgatcaggg accggtacgc
    27541 cgccgcattg agctgtggtt tcgccgccat aaaatcagca atccgcagat ttacgccacc
    27601 gtcggcggtc acgaagcgat ggtctcaatg gtggcgctgg gctgcggcgt ggcgctgctg
    27661 ccggaagtgg tgctggaaaa cagtccggag ccggtgcgca accgggtgat gattttagaa
    27721 cgcagtgatg aaaaaacgcc gtttgagctt ggcgtctgcg cgcaaaaaaa gcggctgcat
    27781 gagccgctaa ttgatgcgtt ctggaagatt ttaccgaatt agttttacgg ccctaccatt
    27841 acccgaacag gcttcccaat acggctaagc atattcacca gagcatcaat ggtgaatttg
    27901 ctgcatttct tgttgacgac atccgaaacg cgcggtcggg atatatgcaa aactgtagca
    27961 acctcggctt gcttcatctg gttttgcgta atccagaggg taatttcttc cattagctgt
    28021 tgtttaatgg ctaacgtgtt ttcgatttca ttcagggaat cagcgtaaaa cttttctgcg
    28081 tcctgcttat gaaaccccaa atcagcaaaa acattaccgc cagatggcgt cacatggcga
    28141 aaatcactat cagttttggc aatcacaagc tgtttctccg ttgttgcacc acccggttat
    28201 aacgcgttct ggcgatgttt ttatcatgct gactggtttg ttgcgtctgt ttttggaaac
    28261 tatgcaaaac gtagagtgct tctgcaaaat tagcgacata cataacgcga tagataccat
    28321 tgttgttacg aatacgaatt tcatttaccc cagccccaat ttctgaaaac ggtttccagt
    28381 catcgggttc aattccatac tgaattttgt gaagctgata accgactgct ttacgtaccg
    28441 ttatgggaaa agccaggaga tcctccagag aagatcccac ccatcgaatt tctttttcat
    28501 tggagagagc tcgggtgagt aacataacat ctttgtgtat aaaattttat acattgtttt
    28561 tagcaggtgc aagtgatggc ggtgctaatg atatggagcc gagtttcacc acaagcagat
    28621 tgggcgcctt ctggaaaacg tctcgcaaaa tgaaatgagt ggatgctccg ggctggcagg
    28681 aaagcccaat aactgaggga agataatatc tggatattag gcccacttta ctttgtgggc
    28741 ccgaaaaact aaacgctgaa ttaacccgcc agaaagaacc ggaacgccgg gttattgctc
    28801 tcatcatggc attcatagcc cagttcatgc agccgggttt cgaaatccgg ctcatgatcg
    28861 cctaactcga acgccgccag cacgcggcca taatcggtac cgtggctgcg gtaatggaat
    28921 agcgaaatat tccagtgcgt gccaagcgta tgaaggaatt tgagcaacgc gccgggcgac
    28981 tccggaaatt cgaaactata caaacgctcc tgtaatggct tggaggggcg cccgccgacc
    29041 atatagcgca catgcagctt cgccatttca tcgtcggaga gatccactac gctataaccg
    29101 ccgtcgcaca gttgggtgat aatctctttt cgttcctcca gcccctgact gacgcgtacg
    29161 ccgacaaaaa tacaggcatg tttcgcgtcg gcaaaacggt agttaaattc ggtgaccata
    29221 cgcccgccaa gcaactggca gaatttgagg aagctcccct tttcttccgg aatggtcacc
    29281 gccagtaacg cttcgcgctg ttcccccagc tcgcagcgtt cagacacata gcgcaagccg
    29341 tggaagttga cgttggcgcc ggaaaggacg tgcgccaggc gttcgccgcg aatattgtgc
    29401 tgggcgatat attttttcat ccccgccagc gccagcgcgc cggacggctc cgccaccgca
    29461 cgcacatctt caaacaggtc tttcatcgcc gcgcagatcg cgtcgctatc gactgtaata
    29521 atgtcgtcga gatattcctg gcacaggcgg aaggtttcgt cgccgatgcg ttttaccgcc
    29581 acgccttcag caaataaccc aacgcgcggg agatccactg gatgaccggc ttccaacgcc
    29641 gctttcaggc aggcggaatc ctccgcttcg acggcaatca ctttgatttg cggcatcaat
    29701 tgtttgatca gtaccgctac gcccgccgcc aggccgccgc cgccaaccgg cacaaagaca
    29761 cgatcgagat gcgaatcctg ctgaagcagt tccagcgcca gcgtgccctg cccggcgatc
    29821 accattgggt gatcaaacgg cggcacccag gtaaaaccct gctgctgcgc cagctcaata
    29881 gctttcgctt tcgcttcatc aaaattagcg ccgtgcaaca gcacttcgcc gccaaaaccg
    29941 cgtaccgcat cgactttaat atccgccgtt gcttttggca tgacgatcag agacttcacg
    30001 ccaagccgcg cggaggagaa cgccacgccc tgtgcatggt tccccgccga cgcggtaatc
    30061 acgccgtggg ctttttgttc ttcggtcaat ccggccatca tcgcgtaagc gccgcgcagc
    30121 ttaaagctat gtaccggctg ccggtcttcg cgtttgacga gaataacgtt gtccagacgt
    30181 gacgagagct tttccatttt ttgcagcggc gtcacctgcg ccgcttcgta tactggcgcg
    30241 cgtagcaccg cgcgcagata ctccgcccct tccggcgcga ctgacagagg ttgagattcc
    30301 gccatcatca acctcccagt ttcgatttat cgcgcaccgc gcctttatcg gcgctggtcg
    30361 ccaggctggc gtaggcacgc agggcaaacg aaacctgacg ctgacgattt ttcggcgtcc
    30421 aggctttatc gccgcgagct tcctgcgcct cgcggcgtgc ggcgatttca gcctcgctca
    30481 actgcaactg aatgctgcgg ttcgggatat caatcgcaat ggtgtcgcca tcttcaatca
    30541 gcgcaatagt gccgccgctg gccgcttccg gcgagacgtg gccgatggaa agacccgaag
    30601 taccgccgga gaaacgccca tcggtgatga gcgcgcaggc tttgcccagc cccatcgact
    30661 tcaggaaact ggtcggatag agcatttcct gcattcccgg cccgcctttc ggcccttcgt
    30721 agcggattac gaccacatcg ccttccacta ctttgccgcc gagaatcgcc tctaccgcat
    30781 cgtcctggct ttcgtaaact ttgacaggac cggtaaattt aaggatgctg tcatccacgc
    30841 ccgcggtttt tacgatgcag ccgttttcgg cgaagttgcc atacagcacc gccagaccgc
    30901 cgtctttgct ataggcatat tccagcgagc ggatgcaacc cgctgcgcgg tcgtcatcca
    30961 gcgaatccca gcgacaatcc tgagagaacg cctgggtagt acggataccg gcagggccag
    31021 cacggaacat ttttttaacc gcttcgtcct gcgtaaccgt gatgtcgtac tgttccagcg
    31081 tttgcggcag cgtcaggcct aatacgtttt tcacgttgcg gttcagcagc ccggcgcgat
    31141 ccagctcgcc taaaataccc agcacaccgc cggcacggtg aacatcttcc atatggtatt
    31201 tctgggtact tggcgccact ttacacagct gcggcacctt gcgggacagc ttgtcgatat
    31261 cactcatggt gaagtcgatt tccgcttcct gcgccgccgc cagtagatgc agaacggtat
    31321 tggtcgaacc gcccatcgca atatccagcg tcatcgcatt ctcaaacgcc gccttgttgg
    31381 cgatgttacg cggcagtgcg ctttcgtcat cctgctcgta atagcgttta gtcagttcaa
    31441 caatccgctt accagcattg aggaacaact gcttccggtc agcatgggtc gccagcagcg
    31501 agccgttgcc cggctgcgac aggcccagcg cttcgatcag gcaattcatg gagttagcgg
    31561 taaacatgcc ggagcaggag ccgcaggttg gacaggcgga gcgttcaacc tggttacttt
    31621 gatcgtcaga gactttcggg tccgctccct gaatcatggc atcaaccaga tcgagcttga
    31681 tgatctgatc ggacagtttg gttttcccgg cttccatcgg gccgccggag acaaagatca
    31741 ccggaatatt caggcgcagc gaggccatga gcatccctgg ggtgattttg tcgcagttgg
    31801 agatacacac catcgcgtca gcgcagtgag cgttcaccat gtactccacg gagtcggcga
    31861 tcagctcgcg cgacggcagt gaatagagca tacccccgtg ccccatggcg atcccgtcat
    31921 ccacggcaat agtgttgaac tctttcgcca caccgccgga agcttcaatc tgttcggcga
    31981 ccagcttacc gagatcgcgc agatgaacgt gacccggcac aaactgagtg aatgagttca
    32041 ccacggtgat aatcggtttg ccaaaatcac tgtcggtcat tccggtggcg cgccacagcg
    32101 cgcgggcacc cgccatatta cgaccatgag tggtggtggc ggaacggtac ttaggcatgc
    32161 tttatttact ccccatcttt tcccttcata cttcacgcca caggtgcgtt ggctgcctca
    32221 ctccagtcac ttactacagt aagctcctgg ggattcgctg cgttgccgcc ttcctgtgac
    32281 gcaaattatt ttgggaaaat attaatttta tttattatga atttaccgga tccaaccagc
    32341 cccatttatc ctcggtttct ccagtgaaga gaccaaagaa ggcttgttgg atacgcttgg
    32401 taacagggcc gcaacggcct tcgcctacct ggataccatc aacgctgcgt accggagtaa
    32461 tttctgccgc agttccggac ataaacactt cgtcggccag atacagcgat tcacgggaca
    32521 gcacctgctc acgcacttca atacccagct ctttcgccag tttgatgatc gcgtcgcgag
    32581 taatgcctgg cagcgcggaa gaggtaaacg gcggagtaaa cagcacgcca tcttttacct
    32641 caaacaggtt ttcgcctgcg ccttcggata tatagccgtt tacatccagg gcgatgcctt
    32701 cctgatagcc gtggcggcgc gcttcgctac ccaccagcag tgaggaaaga tagttcccgc
    32761 ccgctttggc ggcggtcgga atggtgttcg gcgcagcgcg gttccaggaa gaaaccatcg
    32821 catcgatccc ctgatccagc gcttcggcgc ccaggtatgc cccccacggg aacgcggcga
    32881 tgatgacgtc agtggtgtat cccgggggcg ggttaacgcc cataccgaca tcgcctacaa
    32941 ataccaacgg acggatatag gcgctggtca gattattttt acgaattacg tcgcggcagg
    33001 cttccatcag ctcatcaatg ctctgggaaa ccggaaaacg ataaattttt gctgagtcgc
    33061 gcaggcgctg catatgttca cgatgacgaa acactaccgg gcctttgtga gagtcgtagc
    33121 accgaatccc ttcaaatacc gacgtaccgt agtgcagcgc gtgagacatt acgtgaacct
    33181 tcgcgtcttc ccagcgcacc atctcgccat tgaaccaaat gtaatcagct tttttcgtcg
    33241 tcatttttct tccttttgcg ctcaggcgcg gatttgttgt gatgtggcag cgctctggca
    33301 gattgcgaca tgcgcaacat ctaccagttt acttaactga ctaaacagta agtcgaccga
    33361 ccggggactg gcaacggtca attcaatatt tatattctgc gcatcggtcg cggcttccat
    33421 attcatggag cacacctgaa aaccacgatg gcgcaccacg cgtaaaacac gttctaaggt
    33481 ttctggatta aagcgtgccg atacattgac ctgatgttgc atcatgataa tttctccagc
    33541 atttcagagt tactggcgcc aggcggcacc aacggccaga cattttcaag ttcgtcgatt
    33601 gagacgtgaa gcaggtacgg cccttcgctt gccaacatcg tgtcgagtgc cgcttcaacc
    33661 tggtctttac gagtaatgtg ctggcctgga atgccgaagg cgctggccag catgaggaaa
    33721 tcggggttat cggtcagggt ggtttcgcta tatcgctcct ggaaaaacag ttgctgccat
    33781 tgtcgaacca tccctaaccg ctggttgtcg agtaagacta tcttcaacgg taactgcttg
    33841 cgttttacgg tgcccaactc ctgaacattc atcatgaagg agccgtcacc ggagatacag
    33901 ataacggtat cattcggtcg cgctacctgc gcgccaacgg ccgccggtaa gccgaatccc
    33961 atcgtcccca gaccgctgga agtgatgaag ttctccgggc gggtgtaagt catatgctgg
    34021 gctgaccaca tctgatgctg ccccacatcc gtcgtcacca cactgtctgc gggtttgcgt
    34081 tccgacaatt gcttcaacaa caacggcgca tagatagtct cgccaggatg gtcatagcgc
    34141 caggcgtgtt ctgcgcgcag ctctgcacaa gactgacgcc atgcgtcgat cttcagcggt
    34201 tgctgtaatg ccggcaacag cgaatttaaa tcgccctgca acgcgacgtg tgcctgacgc
    34261 agtttgttca tttccgccgg gtcgatatcc atatggatta cgctggcgtt aggcgcaaac
    34321 gtattcagct taccggtcac ccggtcatca aaacgtgcac ccactgcgat cagtaaatca
    34381 cactcttgca ccgcgaaatt agccgcttta gtaccgtgca ttcccagcat gcccagatag
    34441 tacggataat cagcttcaac agcccccaga cctttcagcg tgcaggtaac tggcatttgc
    34501 gttaccgcga taaatttacg cagcgccgga accgccttcg ccataccaac accaccgccg
    34561 acgtacagca tgggtttttt cgcctgttcc agcatctggc gcgcctgttc cacatcagcc
    34621 tgcgggaaag tcgcttcgtt atcgacggta gtaaaccagg gttctagctc accgctggcc
    34681 aactggatat ctttcgggat atccaccaga actggtccgg gacggccagc gttggcgact
    34741 tcaaaagcct ccgccatgat gcgcggcaac tctgccagcg actgcaccag gaagctgtgt
    34801 ttggtacagg ccagcgacag ccctaacaca tccacctcct ggaacgcatc ggtgccgatg
    34861 aacggggcgg aaacctgacc cgtgatcgcg acaacgggga ccgaatctaa caacgcatcc
    34921 gccaggccag tgatcaggtt agtggcgcca gggcccgagg tggcgataca aacaccggtt
    34981 ttgccggtag aacgggcata accgattgcc gccattgcgg caccctgctc gtgtcggcac
    35041 aacaaatgct ccacaccacc gtcatacaac gcgtcgtaaa ccggcataat tgcgccgcca
    35101 ggataaccaa atacggtttt caccccctgc gctcgcaaag catgtaccac ccactgtgcc
    35161 ccgttcatag ttacatcccc gtcgtaaatc ttgagaaaca gaattttatg ctgttattca
    35221 cgctctgctc ctcgcttaag tttttcaggc caaaaaaaac ccccggacct ttcggtgcgg
    35281 gggtcttagt tcgttaaggc ttgatttcta agcctttcct cgtccaagtg cagccccgca
    35341 cggtgggata ataatcacca ccacgctaat cacgaccagg ctaatcactc gtagaagggc
    35401 tgtcattttt gtctattctt gcatcttgtt cgaaggaata cctaaagagt taccataggt
    35461 tttgccaata gcacaagata tttttttaac cacgtttcag ataatgcagg tgaatgccta
    35521 aaagggcttt gttttttata agaaaaatta gcaactgaaa aattttcacg ttttcctccc
    35581 ccttttggtg cgctttacac cctgttttcc ttcttttcgc ttctgcgagc gttcttccag
    35641 tttgatgttt cttacctgaa aatgacgcca aaattcagga atcagccgct aaaaaacaaa
    35701 aagtcagtaa ttcgattttc tcttctattc cgcataatcc acgtaacagg agggattatg
    35761 tcactggcga ttgttcatac tcgcgccgca cttggcgtca atgcgccgcc tatcactata
    35821 gaggtgcata tcagtaatgg attaccggga ttaaccatgg ttggcctacc ggaaaccacg
    35881 gtaaaagagg tgcgtgaccg ggtacgtagt gcgattatta atagcggata tgaatttccg
    35941 gctaaaaaaa taaccattta tgtaaacggg ttaatgaaaa caacaagtta gattaaaaac
    36001 aataagttag gttggtggtc agtggtggtt attacggggt aatgccaacc gctgccgcca
    36061 ctttgtcgcc acttggcagc gttgccagag gattgaaacg gagcgccgtt tccagatgat
    36121 ccggtgccag atgtgcgtaa cgcatagtca tttttatatc gtggtgtccg agaatttttt
    36181 gtaaggccag aatgtttcca cccgacatca tgaagtgcgc cgcaaacgta tggcgcagaa
    36241 cgtgtgtgag ttgaccgcga gggagcacga tagacgtttt ttccatcacg gataaaaatt
    36301 gaaaatagca gtctgtgaag aaattgaacc catcaagcgc catgatctct tcgtaaagct
    36361 ctttactgat agggatgctt ctgtttttct tccccttcgt tcttacaaag gtaattcggt
    36421 atttggtcac ctgtgaacga gtaagattta cggcttctcg ccagcgtgcg cctgtgctta
    36481 agcatatctt aactaccagt gctagaattg ggtcctgacg tttgcaatca gccagtaatt
    36541 caacaatctg ctcatgggta agccatgcca tctctttttc tgcgatggtg aattttcgca
    36601 tgttctccag tgggttcgga tacgaccatt cgcccagacg ggatagttcg ctaaaaacac
    36661 tacttagata gctttgctcc aggttaatgg tgaccgggct tgctcctttc ttccatttct
    36721 cgctgaagta gatctcgcct gtcaggcgtt tatctcgata gtgggcaaac attttagagg
    36781 tgagatcggt tgcaagagga ttgcccagag cgtcaaccat cagcagcaat ttgtcataga
    36841 catgttgccc agcagtcaga gatttaccat gtagtttgaa ccatagctca accacgtctt
    36901 tcagggttcg acgatccact gattcgccca gccatggctt tgattcggtt tcttccatag
    36961 tgtgacgctc aaaagccaga gcttcgcctt tggtggcgaa ttgtttacgc acacgacgcc
    37021 cacttcgtcc ggcggggtaa cattcgcaaa gccatttccc tgtggtgagt tttcgtactg
    37081 ccataaaaaa tgccctccag tagagagcat ttttactgta tgtataacca gtgtcaatgt
    37141 atgaaatcct acgaccatac atctcactga agccataatg aagttggcta ttctttttgc
    37201 tatgtgagca tgtaactttt gcggttaacc tgcggctcat ttttatttta gacgcagata
    37261 taaaagcaaa agttatcgtg agtttttagt acagattttt ttggatttac taatagttcc
    37321 atcattgcaa acgaatttgc catctgaggt acagtgagaa acacctccct ttttccctga
    37381 gcagggataa tttctagcat aggtagttag tgggtttaat aacaaagaac atgacaaaac
    37441 cacaaaaaat accttaccaa gcatagtttc ctcccggtac tatttaacat acttgactgt
    37501 taaacttata attttaccaa ttatttcaat gtcttctatc ttacattcga aggctctgtt
    37561 tccaccctcg acgaagattc ttccaccggg taaacgagta atgtcacgga tcgttacttc
    37621 gccatcaata cttattaccc atttaccatc acgtatatca tcaaattctt tatcacaaat
    37681 aaattcagaa ttgttatctg tgatgacaaa aggtttttta aacgtagagg gtagaaatcc
    37741 cttatcaaaa atataaaaac cgtcttcacg caaggcacca tcagataata catatttagc
    37801 aacttccata gtatttgtat tacctgaagt ttgctttgaa ccatgtccgg ttgtgagcca
    37861 attaagcgag gtgcccgttt caagggcgca ctggattacc cattctgctg ggaatgagtc
    37921 acgcatgtag cgtgtggcga gtgtactttt agagattcct aaatgatcgc acaacgcctg
    37981 tcgagttttg aatccataag cttctaccat gcgctctata gcgcctcgtc cgcctttctc
    38041 caaattcatg gtcactccaa gtgaactttt atcttgacga tttcattgcg cgatcgtatg
    38101 tttatggtgt tcacaaaata caaacgatcc gtattcgtcc tgattaatca tcattaaacg
    38161 aggaatgttg catcatgaga cctaacattt caatcactct taccacgcct catgtgacta
    38221 ttgagcgcta tagcgagctg acagggctgt ccatcgatac catcaatgac atgttggctg
    38281 acggacgcct tatctgtcac cgtttgcgca aagataaaaa acgcgaaaaa gtgatgatca
    38341 acatagcagc catgaccgtt gatgcgcttt cagaatgcaa tctaaacctt aattagttcg
    38401 attctgaaat acatcagagg cattgaccat gtttgattac caagtttcca aacatccaca
    38461 ttttgatgaa gcctgtcgtg catttgcact gcgccacaat ctggtgcaac tggcagaacg
    38521 tgcaggcatg aatgtgcaga ttctgcggaa caagctgaac ccagctcagc ctcatctatt
    38581 aaccgcacca gaaatctggc tgcttaccga tctgactgaa gattcaacgc tggtagatgg
    38641 ttttctggca cagattcatt gtctgccatg tgtaccgatt aatgaggtgg caaaagagaa
    38701 actgccacat tacgtcatga gtgcaaccgc agagatcggg cgtgttgctg caggtgcggt
    38761 atctggcgat gtaaaaacca gtgcaggtcg tcgtgatgct atcagcagca ttaactctgt
    38821 aacacgactg atggcgttgg ctgctgtttc attgcaggcc cgtttacagg ctaaccctgc
    38881 gatggcgagt gcagttgata ccgtgaccgg cctcggtgct tcattcggtt tgctgtgagg
    38941 tgcttatgct gacgaaagaa ccatcatttg catcgctgct ggtaaagcaa agcccggcaa
    39001 tgcactacgg tcacggctgg atcatgggtg aggatggaaa acgctggcat ccatgtcatt
    39061 cacaagatga attgctgtct gaattgacca cgaggaaacg gagaaagtca aaatgtatgc
    39121 agcggaaagt gaagtggttt atcagttttg ttacagaggg gagagttatt cagtacctga
    39181 agatgatttg ctctgttgtt atccgtcgtt gtcgggcgat ggcagttact ttttcacgct
    39241 aaaggatggg acgtttttac ggggagagca ggttaaagag acggtacgaa aaaatgtatc
    39301 tccctttgag cgttaccgta agaacaaaga acgataggtg cgtttggggg atatgaagta
    39361 tggcaattaa tggcgctgcg gcgactgttc cattaagccc cggagaacgc ctgaatggac
    39421 ttaatcacat tgcggaatta agggcgaaag tatttggcct gaatattgag tcagagcttg
    39481 agcggtttat taaagatatg cgtgatccac gggatatcaa taacgaacaa aataaacggg
    39541 cactggctgc catattcttt atggcaaaaa ttccagctga acgtcatagc atcagcatta
    39601 atgagctgac cactgacgaa aagcgggagt tgattaaagc aatgaatcat tttcgtgcag
    39661 tggtgagctt atttcccaga cggctaacca tgccgaatta accaactaat gaaattaatg
    39721 gcgtaaaccc gccgggcatc cctttatcta aattcaggag aattgattat gcgtaatatt
    39781 gaaaccctct cgaccaaaac cggaccggat gacgcagggc ttaatatttt actgacagag
    39841 gctcgtctgg aagaacgccg ggcaagggct gaagcaatgg tagctcgcct tgatagcctg
    39901 gcgtgtcata tcacatcccg ccagctaacc cacgtcgaag cggcagaact gcttcgtgtg
    39961 actgctgaag caatccagaa cgaagcgcag gagatccact aatggctgat gcaatggatc
    40021 tcgtacagca gcgcgttgaa gaagaacgcc aacgccatat ccgtgctgcc cgtgccaaaa
    40081 cgccgggcgt gtcccgcgtg ctttgcattg agtgtgaagc gccaattccg ccagcacgcc
    40141 gccgtgccat tccgggtgtg cagctttgca ttacctgtca ggaaatcgca gagctgaaag
    40201 gcaaacatta caacggaggt gctgtatgag caccatcctg aaatgggcgg gaaataaaac
    40261 tgccataatg tccgaactga aaaaacatct tcctgctggc ccgcgactgg ttgaaccttt
    40321 cgcgggttcc tgtgctgtga tgatggagac ggattatccc agctatctgg ttgcggatat
    40381 taatcctgat ttaatcaacc tctataaaaa ggttgccgct gattgtgaat cgtttatatc
    40441 tcgcgccaga gttttatttg agatcgcaaa cagggaggtg gcttattaca acataaggca
    40501 ggagtttaat tactcaactg aaattactga tttcatgaaa gcggtatatt tcctgtatct
    40561 caatcgtcat ggttaccgtg ggttatgtcg ttataacaag agcgggcatt tcaacattcc
    40621 atacggtaat tataaaaatc cgtatttccc tgaaaaagaa attcgcgcat ttgcagagaa
    40681 agcccagcaa gcaacgttta tctgcgccag ctttgatgaa acgctggcga tgctgcaggt
    40741 gggggatgtg gtgtattgcg atccgcctta tgacggtacg ttttccggct atcacactaa
    40801 cggcttcact gaagatgacc agtatcacct ggcatctgtt cttgaatatc gatcatcaga
    40861 aggtcatcca gtcattgttt ctaacagtga cacatccctg atccgttcgc tgtatcgaaa
    40921 tttcactcac cactacatca aggcaaaacg cagcatcggc gtgtcggctg gcgagagtaa
    40981 atctgcaaca gaaatcatcg ctgtttctgg ggcgcgctgc tgggtgggat ttgatccttc
    41041 gcgtggcgtg gatagttctg ccgtgtacgg agtgcgtgca tgagccatgc tgatatgaac
    41101 aactgcagcg gctttaacga ggccgccgca gcattctcat ggaacagccc gaaaaaggct
    41161 attaaccctt atctggacct ggcggaagtt gcgccggttt ctgcgctttc aaacctgatc
    41221 actctgtacg ctgccgataa cgagcaggaa caactgcgcc gcgaggcact gagtgatcag
    41281 gtttgggagc gttatttctt taatgaatcc cgtgatcctg tccagcgcga aatggagcag
    41341 gataagttca ttagccgggc aaagttggcg catgagcagc agcgttttaa cccggacatg
    41401 gtcattctgg cagacgttaa cgcccagcct tcccatatca gcaggccgct gatgcaacgt
    41461 attgaatact tcagcagcct tggcaggcca aaggcttatt cccgctattt acgtgagacg
    41521 attaagccat gtctggaacg gctggagcat gtacgcgaca gtcagctatc cacttctttt
    41581 cgctttatgg caagccatga agggctggac ggcctgctga ttctgcctga aatgagtcag
    41641 gatcaggtga aacgcctgtc cacccttgtt gctgcgcata tgagcatgtg ccttgatgca
    41701 gcttgtggcg atttgtatgc caccgatgac gttaagccag aagaaatccg caagacatgg
    41761 gaaaaggtgg cagcagaaac cctgcgactg gatgtcatac cgcctgcgtt tgagcaactc
    41821 cgccggaaaa gaaaccgccg taaacccgtg ccctatgaac tcattccggg ttcgctggcg
    41881 cgtatgttgt gcgccgattg gtggtaccgg aaattatgga agatgcgttg cgaatggcgg
    41941 gaagagcagt tgcgtgctgt ttgcctggtc agcaaaaaag catctcccta tgtcagctat
    42001 gaagccatga tgcataaacg tgagcagcgc cgtaagtcgc tggagttttt ccgttctcat
    42061 gaactggtga acgaagacgg cgacacgctg gacatggagg atgtggtaaa cgccagcagc
    42121 agcaaccctg cgcatcgccg caatgagatg atggcctgtg ttaaaggtct ggagcttatc
    42181 gcggaaatgc gcggtgactg cgccgttttc tacaccatca cctgtccgtc acgtttccat
    42241 tccacgctaa ataacggcag gcccaacccg acctggacaa atacgacggt aagacaaagc
    42301 agtgattatc tggtcggcat gtttgctgca tttcgtaagg cgatgcacaa agccggattg
    42361 cgctggtatg gcgtgcgggt ggctgagccg catcatgacg gtacagttca ctggcacctg
    42421 ttgtgtttta tgcgcaaaaa agatcgccgc accattactg ctttgttgcg taagtttgcc
    42481 attcgtgaag accgcgagga gctgggtaat aacacgggac cacgctttaa gtctgagctg
    42541 ataaacccgc gcaaaggtac gccaacaagc tacatcgcga aatacatcag taagaacatt
    42601 gacgggcgtg gtctggctgg cgagatcagc aaggaaacgg gtaaatccct gcgtgataac
    42661 gctgaatacg ttaatgcctg ggcgtctctg catcgtgttc agcaattccg cttctttggc
    42721 attccggggc gtcaggctta ccgtgaactg cgattgctgg ctggtcaggc ggcaaggcaa
    42781 cagggggaca aaaaagcagg tgcgccggta ctggataacc cgcgccttga tgcaatcctg
    42841 gctgctgctg atgctggttg ttttgccacc tacatcatga agcagggcgg cgtactggtt
    42901 ccccgcaaat atcacctcat cagaactgct tatgaaatca acgaagaacc gaccgcatat
    42961 ggcgatcacg gtattcgtat ttatggcatc tggtcaccca ttgcagaggg caagatctgc
    43021 actcatgcgg tgaagtggaa aatggttcgt aaggccgttg acgttcagga ggcggcagcc
    43081 gaccagggcg cttgcgcccc ttggactcgt ggcaataact gtccccttgc tgaaaatttg
    43141 aaccaacatg agaaagataa atcagcagat ggggatacca gaacggacat tacctgcatg
    43201 gatgacaagg aattgcacga ttacctgcac agtatgggca aaaaagagca ccgggaactg
    43261 gcagcaagat tacgcctggt taaaccgaaa cggcgtaaag accacaaaca gcgaattaca
    43321 gagcatcagc gtcagcagct cgtctatgaa ctgaagtcca gaggatttga tggcagcgag
    43381 aaagaagtcg atttactgct tcgtggcggc agtattccgt caggagcagg cctgcgtatc
    43441 ttctatcgga accagcgttt gcaggaagat gataagtggc gggatctgta ttaattacgc
    43501 gggttaacaa ttcgtgctct taataatacc aggcatatca ggctgatgaa cgtaaaaaaa
    43561 cgttttacat cagtaagatt attatatact gtaaatataa acagtggtta tatgtacagt
    43621 attgcgtatg gtgttatagg aggaaagatg caggactatt ttttggagtc tttgaagctc
    43681 cagcgcattg atttttttct taagcttgta gcggctagtg agtgtagcga tgaagagaag
    43741 gggctggctc tgcagtgggt ttctgaattg actgatgagt tgatggcgaa aattcgaagc
    43801 catgaataca gtaggtcgat ggatgtaatc agttgagctt gtttcgttag gacttgataa
    43861 gggaaccgaa aaggggcatt aagccccttt ctcataagtt gatttagttg ttccccaaag
    43921 agccggccat ggctgcatat ttaatttctt cgctgggtat ttcaggatgt agttgaattt
    43981 gcctgatgac atagccagga acttcgtcac tccacagttt cgccgcgtcc ttacagacct
    44041 tatacgcgaa gtctctattc tcaaaggcat aggattttcc gtatgcatat tgctgacagg
    44101 tatgaacata agctccgaag tcgccgtctt tatctggcaa agcacatcca gccaaggcta
    44161 tgatgattgc tactaacgta aaggagaaag ttatacgttt catggtctct ttctaagcgt
    44221 ttagcattat ttaactaagg ggtatctgcc gtgatttggt agtccctgat atatattctc
    44281 agggactatg ctgaagtaga tttaatttcg attatttaga aaggtactta tctctaagtt
    44341 gattcagtct gtcagcatcg cgttctgaaa actcggcgtc accatagatc gatttcccat
    44401 ctgcgtcttc aaggccaatg actgtgacgg taaatatagc atcagccgga actttaagtt
    44461 ttccccaatc agagtatcta ttaggggcta atttccagtt ggctttctca cctggttcca
    44521 gacctccaga aattttatag ttgaagacgt cagagaacca agggacgctt cttcctgggc
    44581 tggcaataac acctttgaag aatactctgg caaccgcttt gtctgttccg ttttcaacgc
    44641 taatatccag aattggctga tcattgccgt aatcctcttt ctggaaataa aaacgggaac
    44701 gttcgacctt gaaggctttc attttttccg cagcctgtgt tgcagaggtt tgtttggctt
    44761 ccagttcttt tatttcttgc agagcctgtt ctttctctct cttctcacgc tcaaggcgaa
    44821 tagtttgtgc gtaatttata acctcatcac cagttttacc ttccaacgct gacttaattt
    44881 ttgtttcgta gacgtcccca gaagacgttc cagcctgcat tagctctctc atgttgattt
    44941 ggctaaaggc aacgacttta actgcatcat caaactgagc ttttttatct gcaggtaagg
    45001 actctcttac tttttgaatg gactctttca tcgactgatc gcttgatgca tcgatcttcg
    45061 gtttgtcaca agcagtaagc agcagagcaa aagcaattac gccagttaat ttcttcatat
    45121 ccctatccca atcgtaaaaa aacaaggcta atcctaacag gattagctgg catgacaaac
    45181 tcatagccat ataggtgtgc tgtataaatt agcgggatga gaaagcctgc gcagaccctc
    45241 atgttgaaac ttgattttag ctcaaaagag ctgacactaa ataactgcgc ggaataatgc
    45301 tccacttcgg ttagcccttg ctgggtaagg cgtggggccg ttttcttcgc ctgatcctgc
    45361 tgtatctggc ctacagtatg ttgcccttac gcgacatgcc acatgtcagt aaacggcagg
    45421 tgtagcagta ttagacgcag ctatttagtg tgtattaagc tggctcatat ttatgactgg
    45481 tttcaaagtt tgaccgattt tcatgtcatg catgtctatg ctgcatgagt tcgcatgatc
    45541 gtttgaggat cggtttggct aagacatgcc agaactggcg ggcttttgct catgtcatgc
    45601 aggtgcatga aaaccactac ataaagcggg caggcgtggc ggggatacga gcgcgcgcta
    45661 agtcatataa gagttatata ttgatttgat tgctggacat gcatacagta tcgctctatc
    45721 atctaataaa tcttagagta tttgacaatg tttggataaa atggaaccta acttattcat
    45781 aatccgctaa acagggatgt cagatgccat accaattggt agagcttagc cccgtagcta
    45841 acgatcttga acagttagga accaaagaga agttttggtt ctatttctcc gatgacactg
    45901 taaatttgca gttgtttaag tactctaggc taggtactgg cgagcattgg tctgaaaagt
    45961 gtgctgctga gttatgtcat ttgcttaaca ttccacatgc tagctatgat ttggcgcgat
    46021 acaatggtcg attcggtgtg gtgactcaga atatcattcc atctggtttc cggatggtaa
    46081 tgggaaatga agtgcttcac agttcgacat tcgattatcc tgggccttta caagccgggg
    46141 aaaagccggt aagggtcaga gaacacactg tcacaagggt attgggttgt ttagataggg
    46201 aatctatcaa gcctcctccg agtgtatatg atctaaccgg gctaaatgca gcagatgtat
    46261 tttgtggatt tttgatgctc gatgcacttg tgagtaatca agatcgccat catgaaaatt
    46321 gggcgatcat gcttaacaat gaaactggtg agcagttttt gtgtccaaca tacgatcatg
    46381 ccgctagttt aggaagggag atgttagatg atgagcgtaa cgaacggctt aatactaaag
    46441 ataaaaatcg acaaatccca tgttttgtaa gaaaagctcg ctctgagcta ttcaaagcaa
    46501 aaactgataa aaagcccttg ctgaccgttg aagcatttca acatgcagtt gaagggagag
    46561 ttgccgctcg cgaccattgg ttaggtaagt tgagcgtttt aacagaagat tccattacag
    46621 atgtgtttaa ccaagtgcct tcatcgtgta tatccgacag tgcacgtaga tttgcaacgt
    46681 taatggtaat ggaaaatcgc agaaggttac tagaatgact aatacaaact ccgtttacgt
    46741 cgcatggcag gcaccagata ccagagactg gcatgttgtt ggtaacttgc aagagcgcaa
    46801 atcggggtat gttttcaggt ataccaaagg tgctcttaaa tctactaaat ttacaaagtt
    46861 tagcggcatg agtgatgttc gtgaaactta tgtttcggaa gaattgtttc ctctttttaa
    46921 aaatcgcctt ttatcaccga gacgtccaga gtatccgagt ttcattaaat ggcttggatt
    46981 tgaagaagat aaggtaaatc ctatcgatat tcttgctcgc tcgggaggct tacgaagcac
    47041 tgatcagctg cagattttca aaaaaattga tgttgattct gatggtaact ttgagcattt
    47101 tttcttctta catggacttg gttacttaaa tagcttagct aatgctcgtg tatctgaatt
    47161 gaaaccgggg caaattttgc gtctttgctt ggatcttcaa aatgaatacg atggggatgc
    47221 tgttgtcgtt cgtgcagata aaccagctga aatcgttggt tactgcccta ggtatttaag
    47281 taatgatatc aagaagatgt tattggatga tccaaaatca atcactttaa cggtcgaaaa
    47341 gattagcgat gatgctcctc ataactatcg gttattatgt aaattatcag gagtactaag
    47401 ccaagcctgt caatcgacgc tgattcctca ggatgagttt gaacctattg agtaaatgaa
    47461 gaaaagccac caaacggtgg cttttcttat tatgggacta tatctagcga gtaggtatta
    47521 aactgtatcg cctccttgcc aagccaatca ttcatctcct gtaatcgctt ttgtagtggc
    47581 attagctcat ttcggacgaa tacacggctt gccttctcca catccccaaa ccccccaaca
    47641 ttattcggca taatccccat catttgcggt ggcacacgat gcgccgccat catgtcgtcc
    47701 cggcttacgt tcttgatgtt cagaaactca tcctttgccg ccacttctga cagcgggatg
    47761 atctgaagcc cgtccttttt gccgttaggc gagtacataa acaggttgcg gaagttgccc
    47821 ggacctttgg cgcttttcat cgcgttgcgg aggttgttca catcctcctg gttctgagcg
    47881 gcatcggtca tgtacattat gaatcctgca tggctgccat taatataata tttgcgtcgg
    47941 aacagcgtgg cggactcgtt gagcagggct gacggaatgg cagaaagata gccgggcagg
    48001 ccgtagatct cctggttgat atcgggttcc atcagatgaa agatgctgcc tttcgtgaac
    48061 tgatacggct gggttgtcat accgtattgc acaaaccagt aggtatccag gtctaacccg
    48121 cgtcgggtgt attttgccag agcaggctca agggcgataa tttcaccgaa ccggttcgtg
    48181 cgtttctcca ggtaggcgtt accaaatacc agatagtcct gcacaaaacg tgaaaaagcc
    48241 tgctggctga gcagcgggtg agggatgtag gtgctggtca gaatgttgca tttcaccgca
    48301 atcggtgagc tatgatgcac ggcggcgcgg aaggttcgcg ccagtccgtc gaaactcact
    48361 ggtggctcat accagcggtc catctgtacg cattccacat agtccagtaa ttcgcggcgg
    48421 tccagaacag gaacgggatc gccgaagctg aatgcttcgg ctgaagtctg gcttttatgc
    48481 tggatctgat tcatcgccgc tgcgcggttt ttcttacgct ttcccatcaa aaaatctcca
    48541 caatattact ggtattggcg gactcgcctt gcagtggttc gttaaacagt gcgtgcattg
    48601 ttgcccaggc cagatcggcg tggctggctt cttcgctgcg gctggcttca taggtcgggc
    48661 ggttgccact ggcggtggtg gcgcgacgga ttgccataaa tgactgcgct atgtcggtgt
    48721 gtccggcgtc aaactccaga cggcggtggc tgataatgtc gtaggccttg agtaccagag
    48781 cgtttttaac gttggggttg tagacaaact cccggacggc aggaaagaac gctttcacgt
    48841 tctcataaac cccgtgaccg acgcctgtcg agtcaatgcc gatataggtc acgttgtact
    48901 gctcggtcag ttttttgatt gcatcagcct gggcgcggaa gtccatcccg cgccactggt
    48961 gacgctcaag aatgcgaaac ttaccgcctg gcacggctgg cggtgccacc accacgcatc
    49021 cggcgctgtc gccgttctgc gtaccttttg ccgggtcata accgatccac acctcgcgcc
    49081 agccaaacgg gcgcagggcc agtgcatgaa agtcggtcca gacttcccaa ctgtccacca
    49141 tgcacgcctg cagttcgctg agcgggaaca cggacgcgag atcgtccacg aactcgcaca
    49201 tcagcaggtt ctggtattcg tccgggctgt actccatgcg tagctggtcg aggtcgaaca
    49261 ggttacagcc gccgcgcacc gcatcttcca cggtgactat ctggcggtat tgcccgtctg
    49321 cgcacagcaa gccgggggcc agattgttgt gggacaggtc gatgtccacc ttatcggctt
    49381 tgttgcgccc acggttaaac agcgcaccgg accagaacgg ataagcactg tgtgtaaggc
    49441 tggatggcgt ggaaaaatag gtttgtcgcc attttttgtg aatagccata ccggaagcca
    49501 ctttgcgcag ctcctggaat ttcggtatcc agaaatattc atccagatac aggttgccgt
    49561 ggtaactctg ggccgtgcgg gcattggtgc cgaggaagta aagcgtggcc ccgttgggaa
    49621 gcaccatcgg atcgcctttc agctccacct ccacttcttt ggcgaagtcg atgatgtact
    49681 gtttaaagac gtgggcctgt gccttactgg cggaaaggaa aatctggtta cgtccggtaa
    49741 gcagggcgtc aatcagggct tcacgggcaa agtaaaaggt cgcgccgatc tggcgtgact
    49801 tcagcaggtt gcggatgcgg ttggtttttc cggcttccca ccagtggcgc tggtagttga
    49861 acatggagga atggaaaatt tcttccagct tctcaatctg ttcatcggtg aaaacgttct
    49921 tttccggctg acggcgtggg cctttgttgc ggttggcgac gttagggttt aagtcggctt
    49981 cgttgccgcc attgttaaac ttgccgatcc gcgcgtggcg ttccgactgg cgcgccagca
    50041 ggtcaatctc tttgaaatct ttcccttctt tgtgctcctt cataatgagc tggcagtagc
    50101 gtgcggcggt ggtgagctgc atctgatcca gcggcccata gtcaccccac ttgtcgcgtt
    50161 ttttccagct gtgaacggtt gcaactttct cgcccagcat ttcagcaatg cgggctacgc
    50221 ggtatccctg aaagtacagc agcatggcct gccgacgggg atcgagatct gcgggtgtca
    50281 gtgtggtgtt catggcacaa acctacagcc ttgaatgaag gctttccccg cctgcggttt
    50341 gtgtggttgt cggtacaaat accgcgcatt gtttcactgc ccccatcacc gcaaccataa
    50401 ggctccagta agttttttct aacggagcac ggctcatgac agtgaaagca aagcgttttc
    50461 gcatcggggt ggaaggtgcc actaccgacg gacgcgaaat ccagcgtgaa tggctggaac
    50521 agatggcagc cagctacaat ccggcggtgt ataccgcgct gattaacctt gagcacatca
    50581 agtcttatct gccggacagc acctttaacc gctacggcaa ggtgacggcg ctgtttgctg
    50641 aagaaatcac ggaaggtccg ctggcgggca agatggcact gtatgccgac gttgagccaa
    50701 cggagtccct ggtggagctg gtgaaaaaag gccagaaatt attcacctct atggaagtca
    50761 gcccgaagtt cgctgatacg ggcaaagcct acctggtcgg cctggctgcc actgatgacc
    50821 ctgccagtct gggcactgaa atgctgacat tcagcgccag tgcagcccat aacccgctgg
    50881 caaaccgcaa gcagaatccc gccaatctct ttaccgccgc agaggaaacg gtgatcgaac
    50941 tggaagaaat ccaggaggac aagctgtccc tgtttgcccg cgtcacggca ctgttcacca
    51001 aaaaagagca gtccgacgat gcccggttct ctgatgtgca taaggccgtg gagttggtcg
    51061 ccactgagca gcaaaacctg agcgcacgca ccgaaaaatc cctgtctgag caggaagaac
    51121 gtctgtctga gctggagact gccctgcagg cacagcagac agcctttaac gaactggtga
    51181 ataagctgag tcatgaagac agccgccagg actaccgcca gcgtgcaaca ggcggtaacg
    51241 cccccgctga cactctgacc aattgctgat ggagcacaaa acccgatgaa gaagaatacc
    51301 cgctttgctt ttaacgctta cctgcagcag ctggcgcgtc tgaacggtgt tgcagttgaa
    51361 gaactgtcca gcaagttcac cgtcgaaccg tccgtgcagc agacgctgga agaccagatc
    51421 cagcagtccg ccgctttcct gacactgatt aacgtcacgc cagtgactga gcagtccggt
    51481 cagttgctgg ggctgggtgt tggcagcacc attgccggaa ccactgatac caccgcgaaa
    51541 gagcgtgaac ctgtcgatcc gacgctgatg gtcgatgtgg aatataaatg cgagcagact
    51601 aactttgaca cggtgctgac ctacgcgaag ctggacctgt gggcgaagtt tcaggatttc
    51661 caggtgcgta tccgtgacgc catcgtgaaa cgtcaggcac tggaccgcat catgatcggc
    51721 tttaacggcg tgaagcgtgc gaaaacctcc aaccgtagcg aaaacccgct gctgcaggat
    51781 gtgaataaag gctggctgca gaaaatccgt gaggatgcac cggatcacgt catgggcagc
    51841 accaccacgg gcggtgaaac tacaccgggt gcggtgaaag tcgggaaagg tggcgaatat
    51901 gccaacctag acgccgtagt gatggatgcc gtcaatgagc ttatcgacgt ggtttaccag
    51961 gacgatgacg atctggtggt tatttgcggg cgtgaactgc tgtctgacaa gtatttcccg
    52021 ctggtcaaca aagagcagga aaacagtgaa aaactggctg ccgatatgat catcagtcag
    52081 aaacgcatgg gtggcctgca ggccgtgcgt gcgccgttct tcccgccgaa tgcgctgcta
    52141 atcacccgtc tggataacct gtccatctac tggcaggaag gcacccgccg ccgttcagtt
    52201 atcgacaacc cgaaacgtga ccggattgaa aactttgaat ccgttaacga agcctatgtg
    52261 gttgaggact accgctgcgc cgcactggtg gaaaacatcc agattggcga tttcagcgcc
    52321 gctgcagcag aagccggagc gtaacctatg agcctgagtc ccgcacggca gcatcgcctg
    52381 cgcgttcagg ctgaacaggc cgcccgcgag ggcggcagcg ttcgccacgc atctggctat
    52441 gacctgatgc tgctgcaact ggcggaagac cgccgccgtc tcaagggcgt tcagtccacg
    52501 gtcaaaaaag cggaaataaa ggtggagctg ctgccgaaat atgccgcctg ggcggagggc
    52561 gtcctggctg ccggaggcgc tcaacaggat gacgtgctga tgtacgtgat gctgtggcgc
    52621 attgatgccg gagattatgc cggggcgctg gagatcgggc gtcatgccct gcgtcatggc
    52681 tgggtgatgc cgctgggtaa ccgcaatgtg cagaccgtgc tggcagagga aatggcagat
    52741 gcagcgcaga gcgcaatgct tgccgccacc ggctttgatg ccgatctgtt gctgcagacg
    52801 ctggagctga cagacggtct ggatatgccg gaccagtcac gggcgcgtct gcataaagcg
    52861 attggcgctg ttctgagtga aagcaatccg gcttccgccc ttaatcatct caaccatgcg
    52921 ttacagctcg atccccgctg tggcgtgaaa aaagacaaac agcagctgga gcgcagactg
    52981 cgcaatgaca gccgctgaca gaacgtgccc ccgcgcacgg gcggcacggg gtggcgaaag
    53041 gcactgccac atcaaaaccc cgtccaccgc cctttatttc aggagaaagc agcatgaagt
    53101 ttgttgcgcc agaacaggca ccggaacagg cggaaatcat cagaaatacg ccgttctggc
    53161 ctgatgtgga cctgtcggag tttcgcagca tgatgcgcac tgatggcacg gtgacgcagc
    53221 cgcgtttaaa gcaggttgcg ctgtcggcaa tttcggaggt caacgcagag ctgtatgagt
    53281 ttcgcagacg ccagcagatg ctggggtatg cctcgctggc agaagtcccg gcggaacaac
    53341 tggacggcaa aagcgagcgc attcagcact atttcaacgc ggtttactgc tgggcacgcg
    53401 ccatgctcaa cgaacgttac caggactatg acgccacggc atccggtgtg aagcggggcg
    53461 aagaactggc agaagccagc ggtgatttgt ggcgtgacgc ccgctgggcc atcagccggg
    53521 tgcaggatgc gccgcactgc acagtggagc ttatctgatg aaagtgcgtg cgcatcagta
    53581 tgacacggtg gacgcgcttt gctggcgtca ttacgggcgc acgcagggtg tcacggagca
    53641 ggtactgaag gcaaatccgg ggcttgccga atacggcccc tttttacctc acgggctgca
    53701 ggtggagctg ccggacattc cgaccaccac caccgtgcag accgtccagc tatgggactg
    53761 aattatgacg cttgagcgaa tcagcgcctt tatcacgtat tgcatcgccg tcgtgctggc
    53821 ctggctgggc gatttgtcca tcaaggatgc ctcaacgctg ggcggcctga tgattggtgt
    53881 gctgatgctg gctatcaact ggtactacaa acacaaagcc taccagcttc tgcgcgacgg
    53941 gcagatctcg cgggaggact atgaatccat caatcgttaa acgctgcctt gtcggggccg
    54001 tgctggctat tgctgccacg ctgccgggtt ttcagcagct tcacacctcc gtggaggggc
    54061 tgaaactgat tgccgattac gaaggttgtc gtctgcagcc gtatcagtgc agcgcgggtg
    54121 tctggaccga cggcattggt aatacgtcag gcgtcattcc cggcaaaacc attacggagc
    54181 gacaggcagc agaagggctg atctccaacg tgctgcgtgt ggagcgggcg ctggaaaggt
    54241 gtgtgaagca acagccgccg cagaaggtgt atgacgctgc ggtgtcgttt gccttcaacg
    54301 tgggaacggg caatgcctgc agttccacac tggtgaaatt actcaatcag cggcgctggg
    54361 cggatgcgtg ccgacagttg ccgcgctggg tttatgtgaa aggtgttttt aatcaggggc
    54421 tggataaccg ccgtgcgcgg gagatggcct ggtgcttaca gggagcaaac tgaaatgaaa
    54481 aagaaattaa tcagcggact gtttctgatg ttatggatgg cgctgttaat cgcagcaatg
    54541 gtgtatccgc aggggatttt tccggtactg gcagcgtccg gcgtttgggt agcctgtttg
    54601 ctgacatggg cggtaattcc ggtagcactg gctgcgttaa ttaagaatgg cccgctctgg
    54661 caggagttaa gggcatcttt gctgaagaca attacccgaa aagaaaacgt atttaccagt
    54721 tgggtgatgc gattgctgat tgttgtaagt ctcgcctgga cggggtgggc tattaccctg
    54781 gtcttttatc tactgaccgt tattgccttc tggatcaccc gtaatcagat ggcgcaacag
    54841 gtagcagcat gaaccggttg ctgctggttg tgctggcgtt attactggcg gcgctgggct
    54901 ggcagacgtg gcggctggct gatgccagcc agaccatcag cacgcaggca gacgagctgc
    54961 agagcaaaag ccaggcactg gcaaagagca acagccagct tatcagcctg tccattctga
    55021 ctgaaaccaa taaccgggag caggcgcggc tctatgccga agcagaacag accagcgcac
    55081 agctgagaca acgacaacgc cggatcgagg aactgaaacg tgagaacgag gatttacgcc
    55141 actgggctga tactcctttg cctgctgaca ttatccggct gcgggaacgt ccggcactca
    55201 ccggaggtgc agcttaccgt cagtggttgt ccgcgagtga cgccgtgtcg gctggagcag
    55261 gcagcaccgc gcactaacgg tgatctgaat gcgttgctgg atgaaacgga ggccgcctgg
    55321 gcggtctgtg cagacaaagt ggacatgatt attgcgtgtc aggagcgaaa cagtgaacaa
    55381 accacaatcc ctgcgccacg ccctcaataa agcggtgcct tatgtccgca ataacccgga
    55441 caaactgcat ctgtttgtgg ataacggttc gctggttgcc acgggggcca gctccatgtc
    55501 atgggagtac cgctataccc tgaacgtggt gatagaggat ttcagcggcg accagaatct
    55561 gctgatggcc ccggttttac tgtggcttcg ggataaccag cccgatgcca tcaataaccc
    55621 ggcgttacgg gaaaagctat tcacctttga tgtggatatt ttgcgcaacg atgtctgtga
    55681 tatcagcctt aatctgcaac tgacggaacg tgtgctggtc agcactgacg gcagtgtgtc
    55741 gagcgttgaa gctgtagcag aacccgatga acctgaagaa atgtggacgg tgaaacgtgg
    55801 ctgaactgca gaaggtggac gactggctga gtgccttgct ggcgaatctg gaaccagcca
    55861 cgagaagccg catgatgcgc cagctggcgc aggaactgcg ccggacacag cagcagaata
    55921 tcaggatgca gcgcaatcca gatggcagca gttatgaacc gcgcagggta acagcacgca
    55981 gcaagaaagg gcgcatcaaa cgtcagatgt ttgcaaagct gcgcaccaca aaatacctga
    56041 aaactgccgc cagcgccgac tctgccagtg tacagtttga aggcaaggtg cagcgtattg
    56101 cccgtgttca ccattacggc ctgcgtgatc gcgtcagtcg caaaggaccg gaggtccgtt
    56161 acgcagagcg tcgcctgctg ggtgtaaatg atgatgttga ggcaatgacc cgcgacatga
    56221 ttctgcaatg gctggcgggg tgatctttgt atcagcactg atacaagttg cagcactgcc
    56281 gcctttcttc ccctgatggc aacctttccc tatgaacgca caattaaccg aaatcatgcg
    56341 ccttatcacc aatctgatcc gcactggtgt agtcaccgaa gtggaccggg aacactggct
    56401 ttgtcgggtg aaaacgggcg accttgaaac caactggatt aactggctga cgctgcgcgc
    56461 gggtaatgcc cgcacatggt ggaaaccatc ggaaggtgag caggtggtgc tactgagtct
    56521 gggcggcaat ctggaaactg cctttgcgct gcccgctgtc tattcgaatc agttcgcacc
    56581 accgtcgacg tcggcagacg cctgcgtgac agaacatcct gacggtggct ggtttgaata
    56641 cgaacccgcc accgggcgct ggtatgtcag gggcatcaaa tcaatggtca ttgaggccgc
    56701 tgacaacatc accatgaaaa ccagtgagtt tgtactggag gctgaccgca cgcgcattaa
    56761 cagcgaagtg gtgatcaatg gtggcgttac ccagggcggc ggagcgatga gttctaacgg
    56821 gatcgtggtt gatgcgcatc agcatactgg cgtcctgaaa ggcggcgata caaccggagg
    56881 cccggtatga cgctttatag cgggatgaac aataccagcg gcaaagtcat tactgatatt
    56941 gaccatctgc gccagtcggt gcgggacatt ctgctgacgc cgcagggtag ccgcattgct
    57001 cgtcgtgaat atggttccct gctgtcgtcg ctaatagacc agccacaaaa tccggcatta
    57061 cgcctgcagg tcatgtcggc agtgtatgtg gcgctgagtc gctgggagcc acggctgacg
    57121 ctggattcca tcaccatcaa cagccatttt gacggttcaa tggtggtgga gctgaccggg
    57181 cggcgtaata acggtgtacc tgtttccctt tccgtatcaa caggagcaga gaatggcagt
    57241 gattgacctt tcgcagttgc ctgcgccgca gattgtggat gtgccggact ttgatacgtt
    57301 gcttgccgaa cgcaaggcag aatttgtggc gcttcatccg aaagatgagc aggaagcagt
    57361 gagccgcaca ctggaactgg aatctgaacc cgtcaccaaa ttgttgcagg agaacgctta
    57421 tcgtgagttg cttctgcgcc agcgcattaa cgaagccgcg caggcggtga tggcggctta
    57481 tgccataggg agcgatctgg accagctcgc tgccaattac aacgtgaaac gcctgacggt
    57541 gacgcctgct gataatgacg ctgtgccgcc cgtcgcggct gtgatggaaa gtgatgaagc
    57601 gttacgcctg cgtgtgcctg cggcttttga agggctttcg gttgcggggc caactgccgc
    57661 ttatgaattt catgcccgaa gcgccgacgg tcgggtggc
//
LOCUS       DAJVBX010000006        53148 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.006, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000006 DAJVBX010000000
VERSION     DAJVBX010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 53148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53148
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.006"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(10..489)
                     /gene="folK"
                     /locus_tag="OPV72_000308"
     CDS             complement(10..489)
                     /gene="folK"
                     /locus_tag="OPV72_000308"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000150775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HCR9912717.1"
                     /translation="MTIAYIALGSNLASPLEQVNAALKAIADIPDSRIVAVSSFYRTP
                     PLGPQDQPDYLNAAVALDTALAPEELLNHTQRIELQQGRVRKAERWGPRTLDLDIMLF
                     GDEVINTDRLTVPHYDMKNRGFMLWPLFEIAPELVFPDDKGLLIELMSQMSPCPDRW"
     gene            complement(486..1904)
                     /gene="pcnB"
                     /locus_tag="OPV72_000309"
     CDS             complement(486..1904)
                     /gene="pcnB"
                     /locus_tag="OPV72_000309"
                     /EC_number="2.7.7.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polynucleotide adenylyltransferase PcnB"
                     /protein_id="HCR9912718.1"
                     /translation="MTLPRCAIFTRVANFCRKVLSREESEAEQAVARPHMTIIPREQH
                     AISRKDISENALKVLYRLNKAGYEAYLVGGGVRDLLLGKKPKDFDVTTNATPDQVRKL
                     FRNCRLVGRRFRLAHVMFGPEIIEVATFRGHNEGSESDRTTSQRGQNGMLLRDNIFGS
                     IEEDAQRRDFTINSLYYSVADFTVRDYVGGMQDLQEGVIRLIGNPETRYREDPVRMLR
                     AVRFAAKLNMRISPETAEPIPRLATLLNDIPPARLFEESLKLLQAGNGFETYQQLREY
                     HLFQPLFPTITRYFTENGDSAMERIIAQVLKNTDNRIRNEMRVNPAFLFAAMFWYPLL
                     EMAQKIAQESGLAYYDAFALAMNDVLDEACRSLAIPKRLTTLTRDIWQLQLRMSRRQG
                     KRAWKLMEHPKFRAAFDLLELRAQVENNTELQRLAQWWAEFQASAPPEQKGMLNELDD
                     DPAPRRRRSRPRKRAPRREGTV"
     gene            complement(2045..2941)
                     /gene="gluQRS"
                     /locus_tag="OPV72_000310"
     CDS             complement(2045..2941)
                     /gene="gluQRS"
                     /locus_tag="OPV72_000310"
                     /EC_number="6.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA glutamyl-Q(34) synthetase GluQRS"
                     /protein_id="HCR9912719.1"
                     /translation="MTDSHYIGRFAPSPSGELHFGSLIAALGSYLQARAQRGVWRVRI
                     EDIDPPREVPGAAATILRQLEHYGLHWDGEVLWQSQRHEAYREALAWLHEQGLSYYCT
                     CPRSRIQRLGGIYDGHCRTLCHGPENAAVRIKQQHPVMHFHDALRGDIQADPQLASED
                     FIIHRRDGLFAYNLAVVVDDHFQGVTEIVRGADLIEPTVRQLSLYKQFGWRAPGYVHL
                     PLALNEQGAKLSKQNHAPALATGDPRPVLVQALRFLGQRDVVAWQEMSVEELLRFAVA
                     HWRLTAVPTSANVNPAFSNASR"
     gene            complement(3010..3465)
                     /gene="dksA"
                     /locus_tag="OPV72_000311"
     CDS             complement(3010..3465)
                     /gene="dksA"
                     /locus_tag="OPV72_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002209354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase-binding protein DksA"
                     /protein_id="HCR9912720.1"
                     /translation="MQEGQNRKTSSLSILAIAGVEPYQEKPGEEYMNEAQLSHFKRIL
                     EAWRNQLRDEVDRTVTHMQDEAANFPDPVDRAAQEEEFSLELRNRDRERKLIKKIEKT
                     LKKVEDEDFGYCESCGVEIGIRRLEARPTADLCIDCKTLAEIREKQMAG"
     gene            complement(3642..4346)
                     /gene="sfsA"
                     /locus_tag="OPV72_000312"
     CDS             complement(3642..4346)
                     /gene="sfsA"
                     /locus_tag="OPV72_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HCR9912721.1"
                     /translation="MLFSPPLQRATLIQRYKRFLADVITPDGTTLTLHCPNTGAMTGC
                     ATPGDTVWYSTSENTKRKYPHTWELTETQSGAFICVNTLRANQLTKEAIQENRLPALA
                     GYNILNSEVKYGAERSRIDFMLQADFRPDCYIEVKSVTLAEKENGYFPDAITERGQKH
                     LRELMGVAAAGHRAVVVFAVLHSAITRFSPARHIDIKYAQLLSEAQNKGVEVLAYKAE
                     LSATKMELNEPVPITL"
     gene            complement(4363..4893)
                     /gene="thpR"
                     /locus_tag="OPV72_000313"
     CDS             complement(4363..4893)
                     /gene="thpR"
                     /locus_tag="OPV72_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA 2',3'-cyclic phosphodiesterase"
                     /protein_id="HCR9912722.1"
                     /translation="MSEPKRLFFAIDLPDDARAQIIAWRAAHFASEDGRPVAAANLHL
                     TLAFLGDVSNDKQRALAQLAGRIRQPGFTLHLDDAGQWLRSRVVWLGMRQPPRGLLQL
                     ANMLRAQAARSGCYQSPQPFHPHITLLRDASHTVAIPPPGFCWSFPVTSFALYASSYG
                     QGRTRYAELQRWTLGE"
     gene            4966..7395
                     /gene="hrpB"
                     /locus_tag="OPV72_000314"
     CDS             4966..7395
                     /gene="hrpB"
                     /locus_tag="OPV72_000314"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414690.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase HrpB"
                     /protein_id="HCR9912723.1"
                     /translation="MTSLPVAAVLPELLTALKTAPQVLLSAPTGAGKSTWLPLQLLQQ
                     GPVAGKILLLEPRRLAARNVAQRLAEALNEKPGETVGYRMRAQSCVGPRTRLEVVTEG
                     VLTRMIQRDPELRGVGLVILDEFHERSLQADLALALLLDIQQGLRDDLRLLIMSATLD
                     NDRLCQRLPDAPTIVSEGRAFPVERRYQPLAAHLRFDEAVAMATAELLRNENGSLLLF
                     LPGVGEIQRVHEHLASRVGSDVLLCPLYGALSLEAQRKAIVPAPAGMRKVVLATNIAE
                     TSLTIEGIRLVVDSAQERVARFDARTGLTRLVTQRISQASMTQRAGRAGRLAPGICLH
                     LLAKEQAERAAAQSDPEILHSDLSGLLMEVLQWGCHDPASLFWLDRPPEVNLQAARRL
                     LLMLGALEGERLSARGRKMAATGNDPRLAAMLVNADEGDSAATAAMLAAILEDPPRGG
                     GTDLSVLFSRRQPGWQQRSQQLLKRLQVRNGEPDSALIMPLLARAFSDRIARRRGQEG
                     RYQLANGMGAMLDADDALGRHEWLIAPLLLQGSASPDARILLAQPLDIASLIQACPDL
                     LRQSDTVEWDEAQGTLKAWRRMRIGQLTVSVQPLAKPSEEELHQAMLNGIRDKGLSVL
                     NWTPEAEQFRLRLHCAAKWLPEYDWPAVDEASLLATLENWLLPHMTGVQSLRSLKSLN
                     VTQALRGLLDYAMLQRLDSELPGHYTVPTGSRITIRYHEDNPPALAVRMQEMFGEAST
                     PTLAQGRVPLVLELLSPAQRPLQITRDLSAFWQGAYREVQKEMKGRYPKHVWPDDPAN
                     TAPTRRTKKYS"
     gene            7536..10058
                     /gene="mrcB"
                     /locus_tag="OPV72_000315"
     CDS             7536..10058
                     /gene="mrcB"
                     /locus_tag="OPV72_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glycosyl
                     transferase/transpeptidase"
                     /protein_id="HCR9912724.1"
                     /translation="MAGNDREPIGRKGKPSRPVKQKVSRRRQHDDDYDDDYEDEEPMP
                     RKGKGKGRKPRGKRGWLWLLLKLFIVFVVLFAIYGVYLDQKIRSRIDGKVWQLPAAVY
                     GRMVNLEPDMPVSKNEMVKLLEATQYRLVTKMTRPGEFTVQANSIEMIRRPFDFPDSK
                     EGQVRARLTFSDGRLETIVNLDNNRQFGFFRLDPRLITMLSSPNGEQRLFVPRSGFPD
                     LLVDTLLATEDRRFYEHDGISLYSIGRAVLANLTAGRTVQGASTLTQQLVKNLFLSSE
                     RSYWRKANEAYMALIMDARYSKDRILELYMNEVYLGQSGDNEIRGFPLASLYYFGRPV
                     EELSLDQQALLVGMVKGASIYNPWRNPKLALERRNLVLRLLQQQKIIDQELYDMLSAR
                     PLGVQPRGGVISPQPAFMQMVRQELQAKLGDKIKDLSGVKIFTTFDSVAQDAAEKAVV
                     EGIPALKKQRKLSDLETAMVVVDRFSGEVRAMVGGAEPQYAGYNRAMQARRSIGSLAK
                     PATYLTALSQPNLYRLNTWIADAPISLRQPNGQVWSPENDDRRYSESGKVMLVDALTR
                     SMNVPTVNLGMALGLPAVTDTWTKLGVPKDQLNPVPAMLLGALNLTPIEVAQAFQTIA
                     SGGNRAPLSALRSVIAEDGKVLYQSYPQAERAVPAQAAYLTLWTMQQVVQRGTGRQLG
                     AKYPGLHLVGKTGTTNNNVDTWFAGIDGSQVTITWVGRDNNQPTKLYGASGAMAIYQR
                     YLANQTPTPLVLTPPEDVVDMGVDYDGNFVCNGGMRTLPVWTDDPNTLCQQGEMMQQQ
                     QQPSGNPFDQSSQPQQPAQQQPPKEEKSDGVAGWIKEMFGGN"
     gene            10351..12542
                     /gene="fhuA"
                     /locus_tag="OPV72_000316"
                     /pseudo
     CDS             10351..12542
                     /gene="fhuA"
                     /locus_tag="OPV72_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459196.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ferrichrome porin FhuA"
     gene            12591..13388
                     /gene="fhuC"
                     /locus_tag="OPV72_000317"
     CDS             12591..13388
                     /gene="fhuC"
                     /locus_tag="OPV72_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe3+-hydroxamate ABC transporter ATP-binding
                     protein FhuC"
                     /protein_id="HCR9912725.1"
                     /translation="MQENHIHSDTTFALRSVAFRVPGRTLLHPLSLTFPAGRVTGLIG
                     HNGSGKSTLLKMLGRHQLPSEGDILLDNQPLASWSSKAFARKVAYLPQQLPQAEGMTV
                     RELVAIGRYPWHGALGRFGVADREKVDEAITLVGLKPLAHRLVDSLSGGERQRAWIAM
                     LVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQQRGLTVVAVLHDINMAARYCDYL
                     VALRGGEMIAQGTPAELMRSDTLEQIYGIPMGILPHPAGAAPVSFVY"
     gene            13388..14278
                     /gene="fhuD"
                     /locus_tag="OPV72_000318"
     CDS             13388..14278
                     /gene="fhuD"
                     /locus_tag="OPV72_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+)-hydroxamate ABC transporter
                     substrate-binding protein FhuD"
                     /protein_id="HCR9912726.1"
                     /translation="MRELYPLTRRRLLTAMALSPLLWQMNTAQAAAIDPRRIVALEWL
                     PVELLLALGITPYGVADVPNYKLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVW
                     SAGYGPSPEKLARIAPGRGFDFSDGKKPLAVARRSLVELAQTLNLEAAAEKHLAQYDR
                     FIASQKPRFIRRGGRPLLMTTLIDPRHMLVLGPNCLFQEVLDEYGIVNAWQGETNFWG
                     STAVSIDRLAMYKEADVICFDHGNSTDMNALMATPLWQAMSFVRAGRFHRVPAVWFYG
                     ATLSTMHFVRILNNVLGGKA"
     gene            14293..16332
                     /gene="fhuB"
                     /locus_tag="OPV72_000319"
     CDS             14293..16332
                     /gene="fhuB"
                     /locus_tag="OPV72_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016504759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+)-hydroxamate ABC transporter permease
                     FhuB"
                     /protein_id="HCR9912727.1"
                     /translation="MPDGGAKNALTDLRFGRFVGRIRRSRHPALLLLALLVAACWLTW
                     VNFSVALPRSQWQQAIWSPDIDIIEQMIFHYSQLPRLAISLLVGAGLGLVGVLFQQVL
                     RNPLAEPTTLGVATGAQLGITVTTLWAIPGALTTQFAALTGACIVGALVFGVAWGKRL
                     SPVTLILAGLVVSLYCGAINQLLVIFHHDQLQSMFLWSTGTLTQTDWSGVQRLWPQLL
                     GGVMLTLLLLRPMTLMGLDDGVARNLGLALSLARLAALSLAIVLSALLVNAVGIIGFI
                     GLFAPLLAKMLGARRLLARLMLAPLIGALILWLSDQIILWLTRVWMEVSTGSVTALIG
                     APLLLWLLPRLKSMSAPDMNASDRVAAERRHVLTFAVAGGALLLLATWVALSFGRDAH
                     GWTWASGTLLEELMPWRWPRILAALMAGVMLAVAGCIIQRLTGNPMASPEVLGISSGA
                     AFGVVLMLFLVPGNAFGWLLPAGSLGAAATLLIIMIAAGRGGFSPQRMLLAGMALSTA
                     FTMLLMMLQASGDPRMADVLTWISGSTYNATGGQVTRTAIVMVILLAVVPLCRRWLTI
                     LPLGGDAARAVGIALTPSRIALLALAACLTATATMTIGPLSFVGLMAPHIARMLGFRR
                     TMPHMVISALAGGVLLVFADWCGRMALFPYQIPAGLLSSFIGAPYFIYLLRKQSR"
     gene            complement(16423..17703)
                     /gene="hemL"
                     /locus_tag="OPV72_000320"
     CDS             complement(16423..17703)
                     /gene="hemL"
                     /locus_tag="OPV72_000320"
                     /EC_number="5.4.3.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-1-semialdehyde 2,1-aminomutase"
                     /protein_id="HCR9912728.1"
                     /translation="MSKSENLYSAARELIPGGVNSPVRAFTGVGGTPLFIEKADGAYL
                     YDVDGKAYIDYVGSWGPMVLGHNHPAIRNAVIEAAERGLSFGAPTEMEVKMAELVTNL
                     VPTMDMVRMVNSGTEATMSAIRLARGFTGRDKIIKFEGCYHGHADCLLVKAGSGALTL
                     GQPNSPGVPADFAKHTLTCTYNDLTSVRAAFEQYPQEIACIIVEPVAGNMNCVPPLPE
                     FLPGLRALCDEFGALLIIDEVMTGFRVALAGAQDYYGVVPDLTCLGKIIGGGMPVGAF
                     GGRRDVMDALAPTGPVYQAGTLSGNPIAMAAGFACLNEVAQPGIHETLDELTTRLAEG
                     LLEAAEEANIPLVVNHVGGMFGIFFTDAESVTCYQDVMACDVERFKRFFHLMLEEGVY
                     LAPSAFEAGFMSVAHSMDDINNTIDAARRVFAKL"
     gene            17873..19294
                     /gene="clcA"
                     /locus_tag="OPV72_000321"
     CDS             17873..19294
                     /gene="clcA"
                     /locus_tag="OPV72_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H(+)/Cl(-) exchange transporter ClcA"
                     /protein_id="HCR9912729.1"
                     /translation="MKTDTSTFLAQQIVRLRRRDQIRRLMQRDKTPLAILFMAAVVGT
                     LTGLVGVAFEKTVSWVQNMRIGALVQVADHAFLLWPLAFILSALLAMVGYFLVRKFAP
                     EAGGSGIPEIEGALEELRPVRWWRVLPVKFIGGMGTLGAGMVLGREGPTVQIGGNLGR
                     MVLDVFRMRSAEARHTLLATGAAAGLSAAFNAPLAGILFIIEEMRPQFRYNLISIKAV
                     FTGVIMSSIVFRIFNGEAPIIEVGKLSDAPVNTLWLYLILGIIFGCVGPVFNSLVLRT
                     QDMFQRFHGGEIKKWVLMGGAIGGLCGILGLIEPAAAGGGFNLIPIAAAGNFSVGLLL
                     FIFITRVVTTLLCFSSGAPGGIFAPMLALGTLLGTAFGMAAAVLFPQYHLEAGTFAIA
                     GMGALMAASVRAPLTGIVLVLEMTDNYQLILPMIITCLGATLLAQFLGGKPLYSTILA
                     RTLAKQDAEQAAKNQNAPAGENT"
     gene            19376..19720
                     /gene="erpA"
                     /locus_tag="OPV72_000322"
     CDS             19376..19720
                     /gene="erpA"
                     /locus_tag="OPV72_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster insertion protein ErpA"
                     /protein_id="HCR9912730.1"
                     /translation="MSDDVALPLQFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSG
                     FQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNA
                     KSTCGCGSSFSI"
     gene            complement(19821..20444)
                     /locus_tag="OPV72_000323"
     CDS             complement(19821..20444)
                     /locus_tag="OPV72_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRIC cation channel family protein"
                     /protein_id="HCR9912731.1"
                     /translation="MLVYWLDIVGTAVFAISGVLLAGKLRMDPFGVLVLGVVTAVGGG
                     TIRDMALDNGPVFWVKDPTDLVVAMVTSMLTILLVRQPRRLPKWMLPVLDAVGLAVFV
                     GIGVNKAFLAETGPLVAVCMGVITGVGGGIIRDVLAREIPMILRTEIYATACIIGGIV
                     HATAFYTFSVPLESASMMGMVVTLFIRLAAIRWHLKLPTFALDENGR"
     gene            complement(20481..21281)
                     /gene="btuF"
                     /locus_tag="OPV72_000324"
     CDS             complement(20481..21281)
                     /gene="btuF"
                     /locus_tag="OPV72_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin B12 ABC transporter substrate-binding
                     protein BtuF"
                     /protein_id="HCR9912732.1"
                     /translation="MAKQMFRALGALLLTLPVWLYAAPRVITLSPANTELAFAAEITP
                     VGVSSYSDYPPEAQKIEQVSTWQGMNLERIVALKPDLVVAWRGGNAERQVNQLTSLGI
                     KVMWVDAVTIEQIADALRQLAAWSPQPEKAQQAAQTLLKEYAALKVEYAGKAKKRVFL
                     QFGMNPLFTSGKGSIQHQVLTTCGGENVFADSRVPWPQVSREQVLARHPQAIIVAGKA
                     GEILKIEQYWGNLLKIPVIPLNSDWFERASPRIILAAKQLCNALSQVN"
     gene            complement(21274..21972)
                     /gene="mtnN"
                     /locus_tag="OPV72_000325"
     CDS             complement(21274..21972)
                     /gene="mtnN"
                     /locus_tag="OPV72_000325"
                     /EC_number="3.2.2.16"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/S-adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HCR9912733.1"
                     /translation="MKIGIIGAMEEEVTLLRDKIDNRQTITLGGCEIYTGQLNGTEVA
                     LLKSGIGKVAAALGATLLLEHCKPDVIINTGSAGGLASTLKVGDIVVSDEARYHDADV
                     TAFGYEYGQLPGCPAGFKADDKLIAAAESCIRELNLNAVRGLIVSGDAFINGSVGLAK
                     IRHNFPDAVAVEMEATAIAHVCHNFNVPFVVVRAISDVADQQSHLSFDEFLAVAAKQS
                     TLMVETLVQKLAHG"
     gene            22057..23574
                     /gene="dgt"
                     /locus_tag="OPV72_000326"
     CDS             22057..23574
                     /gene="dgt"
                     /locus_tag="OPV72_000326"
                     /EC_number="3.1.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dGTPase"
                     /protein_id="HCR9912734.1"
                     /translation="MASIDFRNKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPA
                     IRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKEQNRLEEYGLDAL
                     TGPFESIVEMACLMHDIGNPPFGHFGEAAINDWFRQRLHPEDAESQPLTHDRCVVSSL
                     RLQEGEENLNDIRRKVRQDICHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWW
                     RGPVPDSHRYLMKKPGYYLSEEKYIARLRKELQLAPYSRFPLTWIMEAADDISYCVAD
                     LEDAVEKRIFSVEQLYHHLYHAWGHHEKDSLFELVVGNAWEKSRANTLSRSTEDQFFM
                     YLRVNTLNKLVPYAAQRFIDNLPQIFAGTFNQALLEDASGFSRLLELYKNVAVEHVFS
                     HPDVEQLELQGYRVISGLLDIYQPLLSLSLNDFRELVEKERLKRFPIESRLFQKLSTR
                     HRLAYVEVVSKLPTDSAEYPVLEYYYRCRLIQDYISGMTDLYAWDEYRRLMAVEQ"
     gene            23704..25131
                     /gene="degP"
                     /locus_tag="OPV72_000327"
     CDS             23704..25131
                     /gene="degP"
                     /locus_tag="OPV72_000327"
                     /EC_number="3.4.21.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine endoprotease DegP"
                     /protein_id="HCR9912735.1"
                     /translation="MKKTTLAMSALALSLGLALSPLSATAAETSSSAMTAQQMPSLAP
                     MLEKVMPSVVSINVEGSTTVNTPRMPRNFQQFFGDDSPFCQDGSPFQNSPFCQGGGNG
                     GNGGQQQKFMALGSGVIIDAAKGYVVTNNHVVDNASVIKVQLSDGRKFDAKVVGKDPR
                     SDIALIQIQNPKNLTAIKLADSDALRVGDYTVAIGNPFGLGETVTSGIVSALGRSGLN
                     VENYENFIQTDAAINRGNSGGALVNLNGELIGINTAILAPDGGNIGIGFAIPSNMVKN
                     LTSQMVEYGQVKRGELGIMGTELSSELAKAMKVDAQRGAFVSQVMPNSSAAKAGIKAG
                     DVITSLNGKPISSFAALRAQVGTMPVGSKISLGLLREGKAITVNLELQQSSQSQVDSS
                     TIFSGIEGAEMSNKGQDKGVVVSSVKANSPAAQIGLKKGDVIIGANQQPVKNIAELRK
                     ILDSKPSVLALNIQRGDSSIYLLMQ"
     gene            25284..26441
                     /gene="cdaR"
                     /locus_tag="OPV72_000328"
     CDS             25284..26441
                     /gene="cdaR"
                     /locus_tag="OPV72_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator CdaR"
                     /protein_id="HCR9912736.1"
                     /translation="MAGWHLDTKMAQDIVARTMRIIDTNINVMDARGRIIGSGDRERI
                     GELHEGALLVLSQGRVVDIDNAVARHLHGVRQGINLPLRLEGEIVGVIGLTGEPEHLR
                     KYGELVCMTAEMMLEQSRLMHLLAQDSRLREELVMNLIQAEENTPALVEWAQRLGIDL
                     NQPRVAAVVEVDSGQLGVDSAMAELQQLQNALTTPERNNLIAIVSLTEMVVLKPALNS
                     FGRWDAEDHRKRVEQLISRMKENGQLRFRVALGNYFTGPGSIARSYRTARTTMMVGKQ
                     RMPESRSYFYQDLMLPVLLDSLRGGWQANELARPLVKLKAMDNNGLLRRTLTAWFRHN
                     VQPLATSKALFIHRNTLEYRLNRISELTGLDLGNFDDRLLLYVALQLDEQR"
     gene            complement(26530..26916)
                     /locus_tag="OPV72_000329"
     CDS             complement(26530..26916)
                     /locus_tag="OPV72_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3461 family protein"
                     /protein_id="HCR9912737.1"
                     /translation="MYDNLKSLGITNPEEIDRYSLRQEANNDILKIYFQKDRGEFFAK
                     SVKFKYPRQRKTVVADGIGQGYKEVQEISPNLRYVIDELDQICQRDRSELDLKRKILD
                     DLRHLESVVANKISEIEADLDKLTRK"
     gene            27163..28465
                     /locus_tag="OPV72_000330"
                     /pseudo
     CDS             27163..28465
                     /locus_tag="OPV72_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459217.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MHS family MFS transporter"
     gene            complement(28502..29326)
                     /gene="dapD"
                     /locus_tag="OPV72_000331"
     CDS             complement(28502..29326)
                     /gene="dapD"
                     /locus_tag="OPV72_000331"
                     /EC_number="2.3.1.117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-succinyltransferase"
                     /protein_id="HCR9912738.1"
                     /translation="MQQLQNVIETAFERRADITPANVDTVTREAVKQVISLLDSGALR
                     VAEKIDGQWVTHQWLKKAVLLSFRINDNQVIDGAESRYFDKAPMKFADYDEARFQKEG
                     FRVVPPAAVRQGAFIARNTVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSG
                     GVGIGGVLEPLQANPTIIEDNCFIGARSEVVEGVIVEEGSVISMGVYLGQSTKIYDRE
                     TGEVHYGRVPAGSVVVSGNLPSKDGKYSLYCAVIVKKVDAKTRGKVGINELLRTID"
     gene            complement(29356..32028)
                     /gene="glnD"
                     /locus_tag="OPV72_000332"
     CDS             complement(29356..32028)
                     /gene="glnD"
                     /locus_tag="OPV72_000332"
                     /EC_number="2.7.7.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     uridylyltransferase/uridylyl-removing protein GlnD"
                     /protein_id="HCR9912739.1"
                     /translation="MNTLPEQHANTALPTLPDQPQNPGVWPRAELTVAGIKARIDIFQ
                     HWLGEAFDSGICAEQLIEARTEFIDQLLQRLWIEAGFGQIADLALVAVGGYGRGELHP
                     LSDIDLLILSRKKLPDEQAQKVGELLTLLWDVKLDVGHSVRTLEECLLEGLSDLTVAT
                     NLIETRLLIGDVALFLALQKHIFSEGFWPSDKFYAAKVEEQNQRHQRYHGTSYNLEPD
                     IKSSPGGLRDIHTLQWVARRHFGATSLDEMVGFGFLTPAECAELNECLHILWRIRFAL
                     HLVVSRYDNRLLFDRQLSVAQRLNYSGEGNDPVERMMKDYFRVTRRVSELNQMLLQLF
                     DEAILALPADEKPRPVDDEFQLRGTLIDLRDDTLFIREPQAILRMFYMMVRNSAITGI
                     YSTTLRHLRHARRHLSQPLCYIPEARTLFLSMLRHPGAVSRGLLPMHRHSVLWAYMPQ
                     WSHIVGQMQFDLFHAYTVDEHTIRVMLKLESFAKEETRQRHPLCVDLWPRLPHPELIL
                     IAALFHDIAKGRGGDHSVLGAQDVLTFAELHGLNSRETQLVAWLVRQHLLMSVTAQRR
                     DIQDPEVIKQFAEEVQTETRLRFLVCLTVADICATNETLWNSWKQSLLRELYFATEKQ
                     LRRGMQNTPDMRERVRHHQLQALALLRMDNIDEAALHKIWTRCRANYFVRHSPNQLAW
                     HARHLLQHDLSQPLVLLSPQATRGGTEIFIWSPDRPYLFAAVCAELDRRNLSVHDAQI
                     FTTRDGMAMDTFIVLEPDGSPLAADRHDVIRTGLEQTITQHSWQPPQPRRQPAKLRHF
                     TVETEVNFLPTHTDRKSFMELIALDQPGLLARVGQIFADLGISLHGARITTIGERVED
                     LFIIATADRRALNNVLQLEVQQRLTAALNPNDKG"
     gene            complement(32141..32935)
                     /gene="map"
                     /locus_tag="OPV72_000333"
     CDS             complement(32141..32935)
                     /gene="map"
                     /locus_tag="OPV72_000333"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HCR9912740.1"
                     /translation="MAISIKTSEDIEKMRVAGRLAAEVLEMIEPYIKPGVTTGELDRI
                     CNDYIVNEQHAISACLGYHGYPKSVCISINEVVCHGIPDDAKHLKDGDIVNIDVTVIK
                     DEFHGDTSKMFIVGKPTILGERLCRVTQESLYLGIKMVKPGIRLRTIGAAIQKYAEGE
                     GFSVVREYCGHGIGRGFHEEPQVLHYDADDGGVVLQPGMTFTIEPMLNAGDYRIRTMK
                     DGWTVKTKDRSLSAQYEHTIVVTENGCEILTLRKDDTIPAIITHDE"
     gene            33385..34110
                     /gene="rpsB"
                     /locus_tag="OPV72_000334"
     CDS             33385..34110
                     /gene="rpsB"
                     /locus_tag="OPV72_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HCR9912741.1"
                     /translation="MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLE
                     KTVPMFNEALAELNKISARKGKILFVGTKRAASEAVKEAANSCDQFFVNHRWLGGMLT
                     NWKTVRQSIKRLKDLETQSQDGTFEKLTKKEALMRTRELEKLENSLGGIKDMGGLPDA
                     LFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAIRAVSLYLGAVA
                     ATVREGRSQDLASQAEESFVEAE"
     gene            34368..35219
                     /gene="tsf"
                     /locus_tag="OPV72_000335"
     CDS             34368..35219
                     /gene="tsf"
                     /locus_tag="OPV72_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HCR9912742.1"
                     /translation="MAEITASLVKELRERTGAGMMDCKKALTEANGDIELAIENMRKS
                     GAIKAAKKAGNVAADGVIKTKIDGNVAFILEVNCQTDFVAKDAGFQAFADKVLDAAVA
                     GKITDVEVLKAQFEEERVALVAKIGENINIRRVASLEGDVLGSYQHGARIGVLVAAKG
                     ADEELVKQLAMHVAASKPEFVKPEDVSADVVEKEYQVQLDIAMQSGKPKEIAEKMVEG
                     RMKKFTGEVSLTGQPFVMEPSKSVGQLLKEHNADVTGFIRFEVGEGIEKVETDFAAEV
                     AAMSKQS"
     gene            35364..36089
                     /gene="pyrH"
                     /locus_tag="OPV72_000336"
     CDS             35364..36089
                     /gene="pyrH"
                     /locus_tag="OPV72_000336"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HCR9912743.1"
                     /translation="MATNAKPVYKRILLKLSGEALQGTEGFGIDASILDRMAQEIKEL
                     VELGIQVGVVIGGGNLFRGAGLAKAGMNRVVGDHMGMLATVMNGLAMRDALHRAYVNA
                     RLMSAIPLNGVCDNYSWAEAISLLRNNRVVILSAGTGNPFFTTDSAACLRGIEIEADV
                     VLKATKVDGVFTADPAKDPSATMYDQLTYSEVLDKELKVMDLAAFTLARDHKLPIRVF
                     NMNKPGALRRVVMGEKEGTLITE"
     gene            36236..36793
                     /gene="frr"
                     /locus_tag="OPV72_000337"
     CDS             36236..36793
                     /gene="frr"
                     /locus_tag="OPV72_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HCR9912744.1"
                     /translation="MISDIRKDAEVRMEKCVEAFKTQISKVRTGRASPSLLDGIVVEY
                     YGTPTPLRQLASVTVEDSRTLKINVFDRSMGPAVEKAIMASDLGLNPSSAGTDIRVPL
                     PPLTEERRKDLTKIVRGEAEQARVAVRNVRRDANDKVKALLKDKAISEDDDRRSQEEV
                     QKMTDAAIKKVDAALADKEAELMQF"
     gene            36935..38131
                     /gene="ispC"
                     /locus_tag="OPV72_000338"
     CDS             36935..38131
                     /gene="ispC"
                     /locus_tag="OPV72_000338"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HCR9912745.1"
                     /translation="MKQLTILGSTGSIGCSTLDVVHHNPDSFRVIALVAGKNVARMAE
                     QCLEFSPRYAVMDDTSSAEQLKIMLQQHGSRTEVLSGQQAACEMAALDEVGHVMAAIV
                     GAAGLLPTLAAIRAGKTILLANKESLVTCGRLFMDEVKRSNARLLPVDSEHNAIFQSL
                     PQSIQHNLGYADLEQNGVTSILLTGSGGPFRETPMCDLAAMTPDQACRHPNWSMGRKI
                     SVDSATMMNKGLEYIEARWLFNASARQMEVLIHPQSVIHSMVRYQDGSVLAQLGEPDM
                     RTPIAHTMAWPNRVTSGAQPLDFCKLSALTFSAPDYQRYPCLKLAMEAFEQGQAATTA
                     LNAANEITVAAFLAQQIRFTDIAGLNLAVLERMDLHEPASVDDVLQVDAIAREVARKQ
                     VIRLSR"
     gene            38444..39202
                     /gene="ispU"
                     /locus_tag="OPV72_000339"
                     /gene_synonym="uppS"
     CDS             38444..39202
                     /gene="ispU"
                     /locus_tag="OPV72_000339"
                     /gene_synonym="uppS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2E,6E)-farnesyl-diphosphate-specific
                     ditrans,polycis-undecaprenyl-diphosphate synthase"
                     /protein_id="HCR9912746.1"
                     /translation="MLSATQPVSENLPAHGCRHVAIIMDGNGRWAKKQGKIRAFGHKA
                     GAKSVRRAVSFAANNGIDALTLYAFSSENWNRPAQEVSALMELFVWALDSEVKSLHRH
                     NVRLRIIGDISRFNSRLQERIRKSEALTAHNTGLTLNIAANYGGRWDIVQGVRQLAEL
                     VQAGVLRPDQIDEERLGQQICMHELAPVDLVIRTGGEHRISNFLLWQIAYAELYFTDV
                     LWPDFDEQDFEGALHAFANRERRFGGTEPGDDKA"
     gene            39215..40072
                     /gene="cdsA"
                     /locus_tag="OPV72_000340"
     CDS             39215..40072
                     /gene="cdsA"
                     /locus_tag="OPV72_000340"
                     /EC_number="2.7.7.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HCR9912747.1"
                     /translation="MLKYRLISAFVLIPAVIAALFLLPPVGFAIITLVVCMLAAWEWG
                     QLSGFAARSQRVWLAVLCGLLLALMLFLLPEYHHNIRQPLVEMSLWASLGWWVVALLL
                     VLFYPGSAAIWRNSKTLRLIFGLLTIVPFFWGMLALRAWHYDENHYSGAIWLLYVMIL
                     VWGADSGAYMFGKLFGKHKLAPKVSPGKTWQGFIGGLATAAVISWGYGMWANLNVAPV
                     ILLICSVVAALASVLGDLTESMFKREAGIKDSGHLIPGHGGILDRIDSLTAAVPVFAC
                     LLLLVFRTL"
     gene            40084..41436
                     /gene="rseP"
                     /locus_tag="OPV72_000341"
     CDS             40084..41436
                     /gene="rseP"
                     /locus_tag="OPV72_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma E protease regulator RseP"
                     /protein_id="HCR9912748.1"
                     /translation="MLSILWNLAAFIIALGVLITVHEFGHFWVARRCGVRVERFSIGF
                     GKALWRRTDRYGTEYVIALIPLGGYVKMLDERAEPVAPELRRHAFNNKTVGQRAAIIA
                     AGPVANFIFAIFAYWLVFIIGVPGVRPVIGEITPNSIAAQAQIAPGTELKAVDGIETP
                     DWDAVRLQLVSKIGDQQTTVSVAPFGSDQRQDKTLDLRHWAFEPDKQDPVSSLGIRPR
                     GPQIEPVLSEVQANSAASKAGLQAGDRIVKVDGQPLTQWMKFVTFVRDNPGKPLALEI
                     ERQGSALSLTLTPDTKSVNGKAEGFAGVVPKIIPLPEEYKTIRQYGPFSAILEATDKT
                     WQLMKLTVNMLGKLITGDVKLNNLSGPISIAQGAGMSAEFGVIYYLMFLALISVNLGI
                     INLFPLPVLDGGHLLFLAIEKLKGGPVSERVQDFSYRIGSILLVLLMGLALFNDFSRL
                     "
     gene            41468..43879
                     /gene="bamA"
                     /locus_tag="OPV72_000342"
     CDS             41468..43879
                     /gene="bamA"
                     /locus_tag="OPV72_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamA"
                     /protein_id="HCR9912749.1"
                     /translation="MAMKKLLIASLLFSSATVYGAEGFVVKDIHFEGLQRVAVGAALL
                     SMPVRTGDTVNDEDISNTIRALFATGNFEDVRVLRDGNTLLVQVKERPTIASITFSGN
                     KSVKDDMLKQNLEASGVRVGESLDRTTLSDIEKGLEDFYYSVGKYSASVKAVVTPLPR
                     NRVDLKLVFQEGVSAKIQQINIVGNHAFSTEELISHFQLRDEVPWWNVVGDRKYQKQK
                     LAGDLETLRSYYLDRGYARFNIDSTQVSLTPDKKGIYITVNITEGDQYKLSGVQVSGN
                     LAGHSAEIEKLTKIEPGELYNGTKVTKMEDDIKKLLGRYGYAYPRVQSQPEINDADKT
                     VKLRVNVDAGNRFYVRKIRFEGNDTSKDSVLRREMRQMEGAWLGSDLVDQGKERLNRL
                     GFFETVDTDTQRVPGSPDQVDVVYKVKERNTGSFNFGIGYGTESGVSFQAGVQQDNWL
                     GTGYSVGINGTKNDYQTYSELSVTNPYFTVDGVSLGGRIFYNDFEADDADLSDYTNKS
                     YGTDVTLGFPINEYNTLRAGLGYVHNKLSNMQPQIAMDRYLESMGDPDASDFAADDFT
                     FNYGWTYNKLDRGYFPTDGSRVNLTGKVTIPGSDNEYYKVSLDTATYVPIDNDHKWVV
                     LGRTRWGYGDGLGGKEMPFYENFYAGGSSTVRGFQSNTIGPKAVYKNGAHTSWDDDDD
                     YEDCTQESGCKSDDAVGGNAMAVASLEFITPTPFISEKYANSVRTSFFWDMGTVWDTN
                     WDPSSAPSDVPDYSDPGNIRMSAGIALQWMSPLGPLVFSYAQPFKKYDGDKAEQFQFN
                     IGKTW"
     gene            44002..44487
                     /gene="skp"
                     /locus_tag="OPV72_000343"
                     /gene_synonym="hlpA"
                     /gene_synonym="ompH"
     CDS             44002..44487
                     /gene="skp"
                     /locus_tag="OPV72_000343"
                     /gene_synonym="hlpA"
                     /gene_synonym="ompH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone Skp"
                     /protein_id="HCR9912750.1"
                     /translation="MKKWLLAAGLGLAMVTSAQAADKIAIVNMGNLFQQVAQKTGVSN
                     TLENEFKGRAAELQKMETDLQSKMQRLQSMKAGSDRTKLEKDVMSQRQTFAQKAQAFE
                     KDRARRSNEERNKLVTRIQTAVKKVANDQSIDLVVDANTVAYNSSDVKDITADVLKQV
                     K"
     gene            44491..45516
                     /gene="lpxD"
                     /locus_tag="OPV72_000344"
     CDS             44491..45516
                     /gene="lpxD"
                     /locus_tag="OPV72_000344"
                     /EC_number="2.3.1.191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-3-O-(3-hydroxymyristoyl)glucosamine
                     N-acyltransferase"
                     /protein_id="HCR9912751.1"
                     /translation="MPSIRLADLAEQLDAELHGDGDIVITGVASMQSATTGHITFMVN
                     PKYREHLGLCQASAVVMTQDDLPFAKSAALVVKNPYLTYARMAQILDTTPQPAQNIAP
                     SAVIDATATLGSNVSVGANAVIESGVQLGDNVVIGAGCFVGKNSKIGAGSRLWANVTI
                     YHDIQIGENCLIQSSTVIGADGFGYANDRGNWVKIPQLGRVIIGDRVEIGACTTIDRG
                     ALDDTVIGNGVIIDNQCQIAHNVVIGDNTAVAGGVIMAGSLKIGRYCMIGGASVINGH
                     MEICDKVTVTGMGMVMRPITEPGVYSSGIPLQPNKVWRKTAALVMNIDDMSKRLKAIE
                     RKVNQQD"
     gene            45622..46077
                     /gene="fabZ"
                     /locus_tag="OPV72_000345"
     CDS             45622..46077
                     /gene="fabZ"
                     /locus_tag="OPV72_000345"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HCR9912752.1"
                     /translation="MTTNTHTLQIEEILELLPHRFPFLLVDRVLDFEEGRFLRAVKNV
                     SVNEPFFQGHFPGKPILPGVLILEAMAQATGILAFKSVGKLEPGELYYFAGIDEARFK
                     RPVVPGDQMIMEVTFEKTRRGLTRFKGVALVDGKVVCEATMMCARSREA"
     gene            46081..46869
                     /gene="lpxA"
                     /locus_tag="OPV72_000346"
     CDS             46081..46869
                     /gene="lpxA"
                     /locus_tag="OPV72_000346"
                     /EC_number="2.3.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP--UDP-N-acetylglucosamine
                     O-acyltransferase"
                     /protein_id="HCR9912753.1"
                     /translation="MIDKSVFIHPTAIVEDGAVIGANAHIGPFCIVGPQVEIGEGTVL
                     KSHVVVNGQTKIGRDNEIYQFASIGEVNQDLKYAGEPTRVEIGDRNRIRESVTIHRGT
                     VQGGGLTKVGSDNLLMINAHVAHDCTVGNRCILANNATLAGHVSVDDFAIIGGMTAVH
                     QFCIIGAHVMVGGCSGVAQDVPPYVIAQGNHATPFGVNIEGLKRRGFSREGLVAIRNA
                     YKLLYRSGKTLDEAKLEIAELAEKHPEVKAFTEFFERSTRGPIR"
     gene            46869..48017
                     /gene="lpxB"
                     /locus_tag="OPV72_000347"
     CDS             46869..48017
                     /gene="lpxB"
                     /locus_tag="OPV72_000347"
                     /EC_number="2.4.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid-A-disaccharide synthase"
                     /protein_id="HCR9912754.1"
                     /translation="MAAQRPLTIALVAGETSGDILGAGLIRALKARVPNARFVGVAGP
                     RMQAEGCEAWYEMEELAVMGIVEVLGRLRRLLHIRADLTRRFTELKPDVFVGIDAPDF
                     NITLEGNLKKQGIKTIHYVSPSVWAWRQKRVFKIGRSTHMVLAFLPFEKAFYDKFNVP
                     CRFIGHTMADAMPLDPDKNAARDVLGIPHDAHCLALLPGSRGAEVEMLSADFLKTAQL
                     LRQRYPDLEVVVPLVNAKRREQFEKIKAEVAPDLAVHLLDGMAREAMIASDAALLASG
                     TAALECMLAKCPMVVGYRMKPFTFWLAKRLVKTEYVSLPNLLAGRELVKELLQEECEP
                     QKLAEALLPLLANGKTSHAMHDTFRELHQQIRCNADEQAADAVLELAQ"
     gene            48014..48610
                     /gene="rnhB"
                     /locus_tag="OPV72_000348"
     CDS             48014..48610
                     /gene="rnhB"
                     /locus_tag="OPV72_000348"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HCR9912755.1"
                     /translation="MIEFVYPHTHLVAGVDEVGRGPLVGAVVTAAVILDPARPIVGLN
                     DSKKLSEKRRLSLYDEIKEKALSWSLGRAEAHEIDELNILHATMLAMQRAVAGLHIAP
                     EYVLIDGNRCPELPVPSMAVVKGDSRVAEISAASILAKVTRDAEMAALDIVFPQYGFA
                     QHKGYPTAFHLEKLAQYGATAHHRRSFAPVKRALGLVS"
     gene            48634..52116
                     /gene="dnaE"
                     /locus_tag="OPV72_000349"
     CDS             48634..52116
                     /gene="dnaE"
                     /locus_tag="OPV72_000349"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HCR9912756.1"
                     /translation="MSEPRFVHLRVHSDYSMIDGLAKTGPLVKKAASLGMPALAITDF
                     TNLCGLVKFYGAGHGAGIKPIVGADFNVHNELLGDELTHLTVLAANNTGYQNLTLLIS
                     KAYQRGYGAAGPIIERDWLVELKEGLILLSGGRMGDVGRCLLRGNQALVEECVAFYEA
                     HFPDRYFLELIRTGRQDEETYLHAAVELAEARGLPVVATNDVRFLESDDFDAHEIRVA
                     IHDGFTLDDPKRPRNYSPQQYMRSEEEMCELFSDIPEALENTVEIAKRCNVTVRLGEY
                     FLPQFPTGDMTTEDYLVKKSKEGLEERLAFLFPDEEERKKRRPEYDERLDIELQVINQ
                     MGFPGYFLIVMEFIQWSKDNGVPVGPGRGSGAGSLVAYALKITDLDPLEFDLLFERFL
                     NPERVSMPDFDVDFCMEKRDQVIEHVADMYGRDAVSQIITFGTMAAKAVIRDVGRVLG
                     HPYGFVDRISKLVPPDPGMTLAKAFEAEPQLPEIYEADEEVRALIDMARKLEGVTRNA
                     GKHAGGVVIAPTKITDFAPLYCDEEGKHPVTQFDKSDVEYAGLVKFDFLGLRTLTIIN
                     WALEMINKRRAKNGEPPLDIAAIPLDDKKSFDMLQRSETTAVFQLESRGMKDLIKRLQ
                     PDCFEDMIALVALFRPGPLQSGMVDNFIDRKHGREELSYPDVQWQHESLKPVLEPTYG
                     IILYQEQVMQIAQVLSGYTLGGADMLRRAMGKKKPEEMAKQRSVFEEGAKKNGIDGEL
                     AMKIFDLVEKFAGYGFNKSHSAAYALVSYQTLWLKAHYPAEFMAAVMTADMDNTEKVV
                     GLVDECWRMGLKILPPDINSGLYHFHVNDEGEIVYGIGAIKGVGEGPIEAIIDARNQG
                     GYFRELFDLCARTDTKKLNRRVLEKLIMSGAFDRLGPHRAALMNSLGDALKAADQHAK
                     AEAIGQADMFGVLAEEPEQIEQSYASCQPWPEQVVLDGERETLGLYLTGHPINQYLKE
                     IERYVGGVRLKDMHPTERGKVTTAAGLVIAARVMVTKRGNRIGICTLDDRSGRLEVML
                     FTDALDKYQQLLEKDRILIVSGQVSFDDFSGGLKMTAREVMDIDEAREKYARGLAISL
                     TDRQIDDQLLNRLRQSLEPHRSGTIPVHLYYQRADARARLRFGATWRVSPSDRLLNDL
                     RGLIGSEQVELEFD"
     gene            52129..53088
                     /gene="accA"
                     /locus_tag="OPV72_000350"
     CDS             52129..53088
                     /gene="accA"
                     /locus_tag="OPV72_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HCR9912757.1"
                     /translation="MSLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINIDEEVHRLR
                     EKSVELTRKIFADLGAWQVAQLARHPQRPYTLDYVRLAFDEFDELAGDRAYADDKAIV
                     GGIARLEGRPVMIIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMEMAERFNMPIITF
                     IDTPGAYPGVGAEERGQSEAIARNLREMSRLNVPVICTVIGEGGSGGALAIGVGDKVN
                     MLQYSTYSVISPEGCASILWKSADKAPLAAEAMGIIAPRLKELKLIDSIIPEPLGGAH
                     RNPEAMAASLKAQLLEDLADLDVLSTDDLKNRRYQRLMSYGYA"
BASE COUNT        11878 a        13419 c        15437 g        12414 t
ORIGIN      
        1 gggtatttct taccaacgat cgggacaggg agacatttgg gacatcagct cgatcagcag
       61 acctttatcg tcgggaaaca ccagctccgg agcgatttcg aataacggcc acagcataaa
      121 accgcggttt ttcatgtcgt agtgcggcac ggtcagacgg tcggtgttaa tgacttcatc
      181 gccaaacagc ataatgtcga gatccagcgt gcgcggcccc cagcgttcgg ccttgcgcac
      241 ccggccctgt tgcagctcaa tgcgctgggt atggttaagc aattcttcgg gggcgagagc
      301 ggtatccagc gccaccgcag cgttcaggta atcgggctga tcctgtgggc caagcggcgg
      361 cgtgcggtaa aacgaagaaa ccgcgacgat acggctatcg ggaatgtcgg cgatagcctt
      421 cagggcggca ttgacctgct ccagcggaga ggccagatta ctgccaagcg cgatatacgc
      481 gatcgtcata cggtgccctc gcggcgcggc gcgcgtttgc gcggacgtga acgacggcgg
      541 cgtggagcag gatcgtcgtc cagctcgttg agcatccctt tttgttccgg cggcgcggaa
      601 gcctgaaact cggcccacca ctgcgccaga cgttgcagtt cagtattatt ttccacttgg
      661 gcgcgcagct ccagcaaatc aaacgcggcg cggaatttgg gatgttccat cagcttccag
      721 gcgcgtttgc cctggcgtcg cgacatacgt aactgaagct gccaaatatc acgggtaagc
      781 gtggtaaggc gtttcgggat cgccagtgaa cggcaggctt catccagcac gtcattcatg
      841 gccagcgcga aagcatcgta ataggcaagg ccgctctcct gagcgatttt ttgcgccatc
      901 tccagcagcg gataccagaa catggcggca aacaaaaatg ccgggttaac gcgcatctcg
      961 ttacggatgc ggttatccgt attcttcaac acctgcgcaa tgatgcgttc cattgcgctg
     1021 tcgccgtttt cggtgaaata acgcgtaatg gtaggaaaca acggctggaa gaggtggtat
     1081 tcccgcagtt gttgataggt ttcaaaaccg ttccccgcct gcaacagctt cagcgattct
     1141 tcgaacaggc gcgcgggagg aatgtcgttt agcaaggttg ccagacgcgg gattggctca
     1201 gccgtttcag ggctgatacg catattgagc ttcgcagcga aacgcacggc gcgcagcatt
     1261 cgaaccggat cttcgcggta gcgcgtttcc ggattgccga tcaggcgaat cacgccttct
     1321 tgcagatcct gcatcccgcc gacgtaatcg cgcacggtaa aatccgccac gctgtagtaa
     1381 aggctgttga tggtgaaatc gcggcgctgg gcatcttctt cgatagagcc gaagatgttg
     1441 tcgcgcagca gcataccgtt ttgcccacgc tgggaggtcg tacggtcgct ttcactgcct
     1501 tcattatgac cacgaaacgt tgccacttcg ataatttccg ggccaaacat cacgtgagcc
     1561 aggcggaaac gacgccccac cagacggcaa ttgcggaata atttccgtac ctgatccggt
     1621 gttgcgttgg tggtcacatc gaaatccttc ggctttttac cgagcaggag atcgcggacg
     1681 ccgccgccga ccaggtaggc ttcatagccc gctttgttca gcctgtacag taccttgagg
     1741 gcattttcac tgatatcttt gcgggagata gcgtgctgtt cacgcgggat aatcgtcata
     1801 tgtggacggg cgacggcttg ttctgcctcg ctctcctcgc ggcttaacac cttacggcaa
     1861 aaattagcga ctcgggtaaa aatagcgcac ctcggtagtg tcatacatta ataagatcaa
     1921 cttactctat gtctttcgca ttacggcaga cgggcgtaag agagcaacgc gacctgggct
     1981 gtaagcatca ttaacgccgc agcaatgcga aagacgatga gcaaaaatag cggctaatca
     2041 tagctcagcg agacgcattt gagaatgccg gatttacatt agccgatgtg ggtacggctg
     2101 taagcctcca gtgcgccacc gcaaagcgca gcaactcctc aacagacatc tcctgccacg
     2161 ctacgacgtc gcgttggcct aaaaagcgca atgcctggac cagtaccggg cgcggatcgc
     2221 ctgtcgcaag cgcaggggca tgattttgct tggaaagttt agcgccttgt tcgttgagcg
     2281 ccagcggaag gtgcacgtaa cctggcgcac gccagccaaa ctgtttatac agcgaaagtt
     2341 gtcggacagt aggttcgatt aaatctgcgc cgcggacgat ctccgtcacc ccctgaaaat
     2401 gatcgtcgac caccacggcc aggttataag caaacagtcc gtcgcggcgg tggataataa
     2461 aatcttcgct agccagctgt gggtcagcct ggatgtcgcc gcgcaaggca tcatggaaat
     2521 gcatcactgg atgctgctgt ttaattctga cggcggcatt ctccggcccg tggcataacg
     2581 tccggcaatg gccatcgtaa ataccgccca gacgttgaat gcgcgagcgg gggcaagtgc
     2641 agtagtagct cagtccctgc tcgtgaagcc aggccagcgc ctcgcgataa gcctcatgac
     2701 gctgtgattg ccataagacc tcgccatccc agtgcaggcc gtaatgttcc agctggcgca
     2761 gaatggtcgc tgcggcaccg ggaacttcac gtggggggtc gatatcctct atgcgaacgc
     2821 gccaaactcc gcgttgcgca cgggcttgta gatagctgcc gagggcggcg attaacgagc
     2881 cgaaatgcag ttcgccggat ggcgacggcg cgaaacggcc aatatagtgt gagtcagtca
     2941 tgctgcgggc aataaagaat aaggcgggaa aactcccgcc tgtcataaat agggtagaaa
     3001 cgaacgggat taacccgcca tctgtttttc gcgaatttca gccagcgttt tgcagtcgat
     3061 gcacagatcg gctgttggac gcgcttccag gcggcggata ccaatctcca ctccgcagga
     3121 ctcgcaataa ccgaagtctt catcttccac tttcttcagc gttttctcga tctttttgat
     3181 cagtttgcgc tcacggtcac gattacgtaa ctccaggcta aactcctctt cctgcgcggc
     3241 gcgatcgacc ggatcgggga agttggcggc ttcgtcctgc atgtgcgtca cagtgcgatc
     3301 gacttcatcc cggagttgat tacgccatgc ttcaagaata cgcttgaagt gcgatagctg
     3361 ggcttcgttc atatactctt cgcccggttt ctcctggtac ggctccaccc cagcgatggc
     3421 gagaatactc agggacgatg ttttacggtt ttgcccttct tgcatgttgc ttctccttaa
     3481 cacgcactat cgatccccat gttcggggga aaatcaggtc gctataaata gcagatgctt
     3541 ttccggatag caattatcta aacgtaacac ttgacaaccc tgtgaggaaa agcgtattta
     3601 cgcacgcggc cagaatactt aataatcagg ctgttattcc actacaacgt tatgggcact
     3661 ggttcgttca gttccatttt tgtggctgaa agttctgctt tataagctaa aacttccacg
     3721 cctttattct gagcctcgct caatagctgc gcgtatttta tatcgatatg acgtgcgggg
     3781 gaaaaacgtg taatggcgga gtgcagcaca gcgaacacca ccaccgcgcg atgacctgcc
     3841 gccgcaacgc ccatcaactc ccgaagatgt ttttgccctc gttcggtgat ggcgtcggga
     3901 aaataaccgt tttctttttc cgctaacgtg accgatttca cttcaatata gcagtccggg
     3961 cggaaatctg cctgtaacat aaaatctata cggctgcgct cggcgccata tttgacttca
     4021 ctattcagaa tattgtaccc cgccagcgcc ggcaggcgat tctcctgaat cgcttctttc
     4081 gttagctggt tcgcccgcag cgtattcacg caaatgaatg cgccggattg cgtttcagtc
     4141 aattcccagg tatgcggata tttgcgttta gtattttctg atgtcgaata ccagacggta
     4201 tcgccaggcg tggcgcagcc agtcatcgcg ccggtattag gacagtgcag cgtaagcgtc
     4261 gtaccgtcag gggtgatgac atcagctaaa aaacgtttat agcgctgaat caacgtagcg
     4321 cgttgtaaag ggggtgagaa tagcatcgac attccttgat tattattcgc ccagcgtcca
     4381 gcgctgcagc tcggcatagc gggtacggcc ttgcccatac gaagaggcgt aaagcgcaaa
     4441 cgatgtgacc ggaaatgacc agcaaaagcc cggcggcggg atagccaccg tatggctggc
     4501 gtcgcgcagc agcgtaatat gcgggtgaaa aggctgcggg ctttggtaac aaccgctgcg
     4561 ggcggcctgc gcgcgcagca tattagccaa ctgcaacaac ccgcgcggcg gctggcgcat
     4621 tcccagccac acaacgcgcg aacgcaacca ctgaccggcg tcatctagat gtagcgtaaa
     4681 gcccggttgg cgaattcgtc cggccagttg cgcaagcgcg cgctgcttat cgttactgac
     4741 gtcgcctaaa aaggccagcg tcaggtgtag gttcgccgct gccacggggc gtccgtcttc
     4801 agacgcaaaa tgggcggcgc gccaggcgat aatttgcgcg cgcgcgtcgt cgggtaagtc
     4861 aatagcaaaa aacagccgtt ttggctcaga catagggata ctcggttatg gattaacacg
     4921 atgctacaat gcggcgcaaa gaaagttaac cccgtggagc cgtttgtgac gtcattgccc
     4981 gttgccgccg tattgcctga attgttgaca gccctaaaaa ccgcgccgca ggttttgttg
     5041 tccgcgccta ccggggcggg gaaatccacc tggctgccgt tgcaactcct gcaacagggg
     5101 ccggttgctg gaaaaattct cctgcttgaa ccgcgtcgtc tggcggcgcg taatgtcgcc
     5161 cagcgtctgg cggaagcgtt gaatgaaaag cctggcgaaa cggtaggtta ccggatgcgc
     5221 gcgcaaagct gcgtggggcc gcgtacccgg ctggaagtgg tgaccgaagg cgtattgacc
     5281 agaatgattc agcgcgatcc cgaattacgc ggcgtggggc tggtgatact ggatgaattt
     5341 catgagcgca gtttacaggc ggatttagcg ttggcgctgt tgctggatat ccagcaaggg
     5401 ctccgtgacg atctcaggct gttaatcatg tctgcgacgc tggataacga caggctttgt
     5461 cagcgactgc ctgatgcgcc gacgatcgtc tcggaggggc gcgcgtttcc cgtggagcga
     5521 cgttatcagc cgcttgcggc gcatttgcgt tttgatgaag ccgtcgcgat ggcgacagcg
     5581 gaactgctgc gcaatgaaaa cggttcgctg ctgctatttt tacccggcgt aggcgaaata
     5641 cagcgcgttc atgaacatct ggcgtcgcgg gtagggagcg atgtcctgct ttgtccgctg
     5701 tatggcgcat tgtctctgga agcgcaacgc aaagcgattg ttcccgcacc cgccgggatg
     5761 cgtaaagtgg tattggcgac taacattgcc gaaaccagtt tgacgattga agggattcgt
     5821 ctggtcgtcg atagcgctca ggagcgcgtg gcgcgattcg acgcgcgaac gggactgacg
     5881 cggctggtta cgcagcgtat cagtcaggcg tcaatgacgc agcgcgcggg gcgcgccgga
     5941 cgactggcgc cgggtatctg tttacatctg ctggcaaaag aacaggcgga gcgggcggcg
     6001 gcgcaaagcg atccggaaat cttacacagc gacctctccg gtttgttgat ggaggtgttg
     6061 cagtggggat gtcacgatcc ggcctcgctt ttctggctgg acaggccgcc ggaggtgaat
     6121 cttcaggccg cccgccgttt attattgatg ttaggcgcgc tggagggcga gcgattaagc
     6181 gcgcgggggc ggaaaatggc ggcaacaggt aacgatccgc gcctggcggc gatgttagtc
     6241 aacgccgacg agggcgacag cgccgccact gccgccatgc tcgcggccat ccttgaggac
     6301 ccgccgcgag gcggcggtac ggatttaagc gtgctatttt cgcggcgaca gccgggctgg
     6361 cagcagcgta gccagcagct tttaaaacgg ctgcaggtgc gtaatggcga gccggatagc
     6421 gcgcttatta tgccgctgtt ggccagagcg tttagcgacc gcatcgcgcg gcgtcgcggt
     6481 caggaagggc gctatcagtt agccaatggt atgggcgcga tgttagatgc ggatgacgcg
     6541 ttgggacgtc atgaatggct gatcgcgccg ctgttactgc aaggtagcgc ctcgccggac
     6601 gcccgaatat tgttggcgca gccgctggat attgcctcgc tgattcaggc gtgtcctgat
     6661 ttactgcgcc agtccgacac ggttgaatgg gacgaggcgc agggaacgtt gaaagcatgg
     6721 cgcagaatgc gtattggaca gttgacggtt agcgttcagc cactggcgaa gccgtctgaa
     6781 gaggagcttc atcaggcgat gctgaacggc atccgcgata aaggtctgtc cgtccttaac
     6841 tggacgccgg aagcggagca gttccgtctg cgtctgcact gtgcggcgaa atggctgccg
     6901 gaatatgact ggcctgccgt ggatgaggcg tcgctgctgg cgactctgga aaattggttg
     6961 ctgccgcaca tgacaggcgt acagtcgtta cggagtctga aatctctgaa tgtgactcag
     7021 gcgttacggg gactgcttga ctatgccatg ctgcaacgtc tggatagtga actgcctggg
     7081 cattacactg tgccgacggg aagccgaata acgattcgtt atcatgaaga taacccgccc
     7141 gcgctggcgg tcagaatgca ggaaatgttc ggcgaggcaa gtacgccgac acttgcgcag
     7201 gggcgagtgc cgctggtgct ggaactgctt tcgccagcgc agcgaccgct acagattacg
     7261 cgcgatttaa gcgctttctg gcagggggcg tatcgcgaag tgcaaaaaga gatgaagggg
     7321 cgttacccca aacatgtctg gccggacgat ccggcgaata cggctccaac gcggcgcacg
     7381 aagaagtatt cgtgacgtgt tatacgttgc ctccaggccg gataaggcgt taatcgccat
     7441 ccggcaaaaa ggtaaattga gagatttctt cttctgtcgt ctggcggaag aatagagaat
     7501 cgggcctttg cgcctgtatg ttgcggagaa aaagcatggc ggggaatgac cgcgagccga
     7561 ttggacgtaa ggggaaaccg tcacgtcctg tgaaacaaaa ggtgagccgt cgtcggcagc
     7621 atgacgacga ttatgatgat gactatgagg atgaagaacc gatgccgcgt aaaggtaagg
     7681 gcaaagggcg taagcctcgt ggcaagcgcg gctggctgtg gctattgcta aaactgttta
     7741 tcgtttttgt ggtgctgttc gccatttacg gcgtctatct ggatcaaaaa atccgcagcc
     7801 gtattgatgg caaggtctgg cagcttccgg cggcggtata tggccggatg gtgaaccttg
     7861 agccagacat gcctgtcagc aaaaacgaga tggtgaaatt gctggaagcg acgcagtatc
     7921 gtctggtgac gaagatgacc cgtcccggcg aatttaccgt gcaggccaat agcattgaga
     7981 tgatccgtcg tccgtttgac ttcccggaca gcaaagaagg gcaggtgcgc gcgcggctga
     8041 cgttcagtga cgggcgtctg gaaaccatcg tcaatctgga taacaaccgc cagtttggct
     8101 tcttccgcct cgatccgcgg cttatcacca tgctttcttc gccaaatggc gagcagcgtt
     8161 tattcgtccc gcgcagcggt ttcccggatc tgctggtcga tacgctgttg gcgacggaag
     8221 accgtcgttt ctatgagcat gatggcatta gtctttactc tatcgggcgt gcggtgctgg
     8281 ccaacctgac ggcgggacgc acggtgcagg gggccagtac gctgacccag cagctggtga
     8341 agaacctgtt cctctccagc gaaagatcat actggcgtaa agcgaatgaa gcctacatgg
     8401 cgctgatcat ggatgcccgt tacagtaaag atcgtattct tgagctgtac atgaacgagg
     8461 tctacctcgg tcaaagcggg gataatgaaa ttcgcggttt tccgctggcg agcctgtatt
     8521 actttggtcg tccggtagag gaactgagcc tcgatcagca ggcgttactg gtggggatgg
     8581 taaaaggggc gtcgatttat aacccgtggc gtaacccgaa actggcgctg gagcgtcgta
     8641 acctagtgtt acgcctgtta cagcagcaga aaatcatcga tcaggaactc tatgacatgc
     8701 tgagcgcgcg tccgcttggc gtacagccgc gcggcggcgt tatttcaccg cagccagcgt
     8761 ttatgcagat ggttcgtcag gaactgcagg cgaagctggg ggataaaatt aaagatctct
     8821 ccggcgtgaa gatcttcacc acctttgact ccgtggcgca ggatgccgca gaaaaagccg
     8881 ttgtcgaagg cattccggcg ttgaagaagc agcgtaaatt gagcgatctg gaaactgcga
     8941 tggtggtagt ggatcgcttt agcggcgagg tacgcgcgat ggttggcggg gcggagccgc
     9001 agtatgctgg ctataaccgt gccatgcagg cacgccgttc catcgggtcg ctggcgaaac
     9061 cggcgaccta tctgaccgcg ttaagtcagc cgaacttata ccgtctgaac acctggattg
     9121 ccgatgcgcc gatttctctg cgccagccga atggtcaggt ctggtcgccg gagaacgacg
     9181 atcgtcgcta cagcgaaagc gggaaagtga tgctggtgga tgcgttaact cgttcaatga
     9241 acgtaccgac ggtcaatctg gggatggcgt taggtttacc ggcggtaacc gatacctgga
     9301 cgaagctcgg cgtgccgaaa gatcagctca atccggttcc ggcgatgctg ttaggggcgc
     9361 tgaacctgac gccgatcgaa gtggcgcaag cgttccagac tatcgccagc ggcggaaatc
     9421 gcgcgccgtt atcagcgctg cgttcggtta ttgcggaaga tggtaaagtg ctgtaccaaa
     9481 gttatccgca agctgaacgc gccgtaccgg cacaggcggc ttacctgacg ctctggacaa
     9541 tgcagcaggt cgtccagcgt ggtacggggc gtcagcttgg cgcgaaatat ccgggtctgc
     9601 atctggtggg taaaaccggg acgacaaaca acaatgtcga tacctggttt gccggtatcg
     9661 acggcagcca ggtgactatc acctgggtag gccgtgataa caaccagcca acgaaattgt
     9721 acggtgccag cggcgcgatg gcgatttacc agcgctatct ggcgaaccag acgccgacgc
     9781 ctttagttct gacgccgccg gaagatgtgg tggatatggg cgttgattac gacggtaatt
     9841 ttgtctgtaa cggcggtatg cgcactctgc cggtctggac ggacgatcca aatacgctgt
     9901 gccagcaggg cgagatgatg cagcagcaac agcagccgtc aggcaatccg ttcgatcagt
     9961 cgtctcagcc gcagcagcct gcgcagcaac agccgccgaa agaagagaag agcgacggcg
    10021 ttgccggctg gattaaggag atgtttggcg gcaattaatc acggtaatag tgccgggtgg
    10081 cgctgtgctt actcggtcca caccgttacg accccattat gtgcgacgta ggccgaataa
    10141 gacgcttaca tcgccatccg gcaaatcctc cataaataac atttcagtct aatttattaa
    10201 cccttccttt tcatctggtt gtttcttaac cccttagttt tcgtagggcc gcgtatcgct
    10261 tgccattgcg acgatatttc gcctatcatg ctgcggttat aataataatt atcgtttacg
    10321 ttatcattca ctttcatcag agatatacca atggcgcgtc ttaaaattgc tcagccaaac
    10381 tcctcactgc gtaaaatcgc agttgtagta gccacagcgg ttagcggcat gtctgtctat
    10441 gcacaggcgg cggttcaacc gaaagaagaa accattaccg taaccgcagc gcctgcgccg
    10501 caggaaagtg cctggggacc ggctccgacc atcgccgcga agcgttccgc cactaccacc
    10561 aaaactgata catctatcga aaaaacgcca cagtcggttt cggtggtcac taacgaagag
    10621 atgcagatgc atcaattcca gtcagtaaaa gaagcgttgg gttacacgcc gggcgtaact
    10681 gtaagcagtc gcggcgcttc caatacctat gacttcgtga ttatccgtgg cttctcttcc
    10741 gtcggcctga gccagaataa ctatctctgg atggcctgaa attgcagggt aacttctaca
    10801 acgatgcggt tattgatcca tccctgcttg agcgtgttga gttgatgcgt ggcccaacgt
    10861 ccgttctcta tggtaagagc aacccgggcg gtatcatttc gatggttagc aagcggccga
    10921 ctactgagcc gctgaaagaa attcaattca aaatggggac ggacaatttg ttccagaccg
    10981 gttttgattt tagtgattcc ctggatgaca acggtgagtt ctcatatcgt ctgacggggc
    11041 tggcgcgctc gacaaatgag cagcaaaaga gttctgagtc gcagcgctat gcgattgcgc
    11101 cctcttttac ctggcgtcct gatgagaaaa cgaattttac gttcctttct tatttccaga
    11161 acgaaccaga gactggctac tacggctggc tgccgaaaga gggaacggtt gaaccgttac
    11221 cgaatggtaa acgcttgcca acagatttca atgaaggggc gtcaaacaac acctattctc
    11281 gtaacgagaa aatggtggga tacagtttcg agcatggctt caacgacact tttaccgtgc
    11341 gccagaattt acgttttgtc gaaatgaaaa ccgcgcaaaa aagcgtctat ggcacgggga
    11401 ttgcggcgga cggccatacg cttaaccgcg gtactatcgt tgacaacgag cgtttacaga
    11461 atttcagcgt agatacacaa ctggaaagta aattcgcgac cggcgatatt gatcatacgt
    11521 tgctgacggg tgtcgatttc atgcgtatgc gtaatgatat taacgcgacg tttggtagcg
    11581 cgccgtcaat cgatctctat aacaattacc atcctgaata ctttgctttc ggcggcgctg
    11641 agccgtacca gatgaacgaa agtaaacaaa cagccttata tgttcaggat caggcggaat
    11701 ggaataagtg ggtatttact ctcggcggcc gttatgactg gtctaaacaa gcgataacgg
    11761 tgcgtcagaa ttccactacg ccgacagaag gatatattga acgtaatgac caccagttca
    11821 cctggcgcgg tggcgtaaac tacgtattcg ataatggaat ttcaccttac ttcagctata
    11881 gccaatcttt cgagccaagc gccttcgatt tgtggagcac cccacgtgtt tcttacaagc
    11941 cgtcaaaagg cgagcaatat gaagcagggg tgaaatatgt accgaaagac atgccagttg
    12001 ttgttacggg tgccgtttat cagctgacca aaaccaataa cctgaccgcc gatccaacca
    12061 acccattagc gcaggtgccg gcaggcgaaa ttcgtgcgcg aggtgtagag ctggaagcca
    12121 aagcagcatt gacggctaat atcaatatga cggcgtctta cacttatact gatgctgaat
    12181 acacgaaaga cactaacctg aaagggaata cgccagagca ggtgcctgaa cacatggcgt
    12241 cgttgtgggg cgattacacc ttcaacgatg gtccgttgtc aggtttaacg ctgggaacag
    12301 gcggtcgttt tattggttcc agttacggcg atccggccaa tagcttcaag gtaggcagcg
    12361 cagcggtgat ggatgcggtc gtcaagtacg atctggcgcg ttttggtatg gcgggctcca
    12421 gcattgcggt taacgttaat aatctgctcg accgcgaata cgtcgccagc tgcttccaga
    12481 cctacggctg tttctggggc gcagaacgtc aggtcgttgc aacggcaacc ttccgtttct
    12541 aatttctttt tgggcacggc ttgccgtgcc cgttttacaa gttggctgcg atgcaggaaa
    12601 accacattca ttccgatacc acctttgcgc tgcgaagcgt cgcttttcgt gtgccgggcc
    12661 gcacgctttt acaccccctc tcgttaacgt ttcccgcagg tcgagtcacc ggacttatcg
    12721 gccataatgg ttccggtaaa tccacgctgt taaaaatgct gggccgccat cagctgcctt
    12781 ccgaagggga tattctgctc gacaatcagc cgctggcgag ctggagcagc aaggcgtttg
    12841 cccgcaaagt tgcctatctg cctcaacaat tgccgcaggc ggaaggaatg acggtgcgcg
    12901 aactggtggc gattggccgc tatccgtggc acggcgcgtt gggacgcttt ggcgtcgcgg
    12961 accgggaaaa agtagacgag gcgattacgc tggtcggctt aaaaccgctg gcgcatcgtc
    13021 tggtcgatag cctgtccggc ggtgaacgcc agcgcgcgtg gattgccatg ctggtcgcgc
    13081 aggacagccg ttgtctgctg ctggatgagc cgacgtcagc gctggatatc gcccatcagg
    13141 ttgacgtgct ggcgctggtg catcgtttaa gccaacagcg cgggctgacg gtggttgcgg
    13201 tgctgcacga tatcaacatg gcggcccgct actgtgatta tttagtagcg ctacgcggcg
    13261 gtgaaatgat tgcgcaagga acgcctgcgg aactgatgcg cagtgacacg ctggaacaga
    13321 tttacggtat cccgatgggt atccttccgc atccggcggg cgccgcgcct gtgagttttg
    13381 tgtattaatg cgtgagttat atcctcttac tcgccgccgt ttattaacgg cgatggcgct
    13441 ctcgccgctg ctgtggcaaa tgaatacggc gcaggctgcc gctatcgatc cccgccggat
    13501 tgtggcgctg gagtggctgc cggttgagct gctgctggcg ctcggtatta cgccttatgg
    13561 tgtggcggac gtgccaaatt ataagctgtg ggttagcgaa ccgccgttgc cggattcggt
    13621 gattgatgtg ggtcttcgca ctgaacccaa tctcgaactg ctgacggaga tgaagccgtc
    13681 gtttatggtg tggtcggcag gttacggacc ctcgccggag aaactggcgc ggatcgcgcc
    13741 ggggcgcggg ttcgatttta gcgacggcaa aaagccgctg gcggtggccc gacgctcgct
    13801 ggttgaactg gcgcagacgc tgaatctgga agctgcggca gaaaaacatc tggcgcaata
    13861 cgatcgcttc atcgccagcc agaagccacg ttttatccgc cgcgggggac gtccgttact
    13921 gatgacgacg cttatcgatc cgcggcatat gctggtgctc ggcccgaatt gcctgttcca
    13981 ggaggtgctg gacgagtatg gcatcgtcaa tgcctggcag ggtgaaacca acttttgggg
    14041 cagtacggcg gtcagcatcg atcggctggc gatgtataaa gaagcggatg tgatctgctt
    14101 cgatcacggg aatagcaccg atatgaacgc gctgatggca acgccgctgt ggcaggccat
    14161 gtcgtttgtc cgcgccgggc gttttcaccg ggtgcccgcc gtttggttct atggcgcgac
    14221 cctctccacg atgcattttg tccgcatcct gaataacgtg ttgggaggca aagcgtgagc
    14281 agaaaacgtg aaataccgga tggcggtgcg aaaaacgcct taaccgacct acggttcggg
    14341 cgctttgtag gccggataag gcgaagccgc catccggcgt tgctgttatt ggcgctgttg
    14401 gttgccgcct gctggctgac atgggttaac ttctccgttg cgctaccgcg cagtcagtgg
    14461 caacaggcta tctggtcacc agatatcgac atcattgagc agatgatttt tcattacagc
    14521 cagctgccaa gactggcgat ttcgctgctg gtgggcgcgg ggcttgggct ggtaggcgtc
    14581 ctgttccagc aagtattacg taacccgctg gcggaaccga ccacgctggg cgtggcgacc
    14641 ggcgcgcaat tggggatcac ggtgactacg ctttgggcga ttcccggcgc gctgaccacg
    14701 cagtttgccg ccctgacggg agcctgcatc gtcggcgcgc tggtgttcgg cgtggcgtgg
    14761 ggcaaacgtc tgtcgccagt gaccctgatc ctcgccgggc tggtggtcag cctctattgt
    14821 ggcgcaatca accagttact ggtgattttc caccacgatc agttgcaaag catgttttta
    14881 tggagcactg gaacgctaac gcaaaccgac tggagcggcg tgcagcgtct gtggccgcag
    14941 ttgctgggcg gcgtgatgct cacgttattg ttgttacgtc cgatgacgct gatggggctg
    15001 gatgacggcg ttgcgcgtaa tctggggctg gcgctgtcgt tagcgcgtct ggcggcgttg
    15061 tcgctggcga ttgtgttgag cgcgctgctg gtcaacgcgg tgggcattat cggttttatc
    15121 ggcctgtttg cgccgctgct ggcgaaaatg cttggcgcaa gacgtctgct ggcgcgcctg
    15181 atgctggcgc cgctcattgg ggcgcttatt ttatggctat ccgatcagat tatcctttgg
    15241 ctaacccgcg tatggatgga agtctccacc gggtcagtga cggcgttaat cggcgcgccg
    15301 ctgctcctat ggctgctgcc gcggcttaaa agcatgagcg cgccggatat gaacgccagc
    15361 gatcgtgtgg cggcggagcg tcgacatgtc ctcacttttg ccgttgccgg tggcgcgctc
    15421 ctgctgctgg caacatgggt cgcgctctct tttggtcgcg acgcgcacgg ctggacgtgg
    15481 gcgagcggaa cgctgcttga agaactgatg ccgtggcgct ggccgcggat actggcggcg
    15541 ttaatggcgg gcgtcatgct ggcggtggcg ggctgcatta ttcagcgtct gaccggtaac
    15601 ccaatggcca gcccggaagt gctggggatc agttccggag ccgcgtttgg cgtggtgttg
    15661 atgctgtttt tggtgccggg gaatgctttc ggttggctac tgcctgccgg aagcctgggc
    15721 gcggcggcga cactgctgat tattatgata gccgccgggc gcggcggttt ctcgccgcaa
    15781 cggatgttgc tggcggggat ggcgctcagc accgcgttta ccatgctgct aatgatgctc
    15841 caggcgagcg gcgatccgcg gatggcggat gtgttgacct ggatctcagg atctacctat
    15901 aacgccactg gcgggcaggt tacgcgaacc gcgatcgtga tggtgatttt gctggccgtt
    15961 gtgccgttgt gtcgccgctg gttaacgatt ttgccactgg gcggcgatgc cgcgcgcgcg
    16021 gtgggcatag cgcttacgcc gtcgcgtatc gcgctgctgg cgttggcggc ttgtttgacg
    16081 gcaaccgcga cgatgaccat tgggccgctg agtttcgttg gattgatggc gccgcatatt
    16141 gcgcggatgc tcggttttcg ccggacgatg ccgcatatgg tcatctcagc gctggcaggg
    16201 ggcgttttat tggtctttgc cgactggtgc ggcaggatgg cgctatttcc gtatcagatc
    16261 ccggcgggac tgctttcaag ctttattggc gcgccgtact ttatctattt gctacgtaaa
    16321 cagagccgct gagtttgccg gatggcggca taaatgcctt atccggcctg cggtgtagaa
    16381 tgtaggccgg gtaagcgtaa gcgtcacccg gcaattcatc ctttacaatt tcgcaaacac
    16441 ccgacgcgcg gcgtcaatag tattattaat gtcgtccatg ctgtgtgcga ccgacataaa
    16501 acccgcctca aacgccgatg gcgccagata cacgccttcc tccagcatca ggtggaagaa
    16561 acgcttaaag cgttccacgt cgcacgccat cacgtcctga tagcaagtta cgctctcagc
    16621 gtcggtgaag aaaatcccga acatgccgcc gacatggtta accaccagcg gaatattcgc
    16681 ttcttcggca gcttccagca aaccttccgc caggcgggtg gtgagctcat ccagcgtttc
    16741 atgaatgccg ggctgggcga cttcattcag gcaggcgaaa ccggccgcca tcgcaatcgg
    16801 gttgccggaa agggtgcccg cctggtaaac cgggcccgtc ggcgccagcg catccattac
    16861 atcgcgacga ccgccaaacg cgcctaccgg catcccgccg ccgatgattt tacccagaca
    16921 ggtcaggtcc ggcacgacgc cgtagtaatc ctgggctccg gccagcgcta cgcgaaaacc
    16981 ggtcattact tcgtcgataa tcagcagcgc gccgaactca tcgcacaagg cacgcaggcc
    17041 cggcaggaat tccggcagcg gcgggacgca gttcatattg cccgccacgg gttcgacgat
    17101 gatacaggcg atttcctgcg gatattgttc aaacgccgcg cgcactgacg tcagatcgtt
    17161 ataagtgcag gtcagcgtat gtttcgcgaa atctgccggc acgcccggcg agttcggctg
    17221 accgagcgtc agcgcgccag aaccggcttt gaccagcaga cagtctgcgt ggccgtggta
    17281 gcagccttcg aatttgataa tcttatcgcg gccagtaaaa ccacgcgcca ggcgaatcgc
    17341 gctcatcgtc gcttcggtgc cggagttcac catgcgcacc atgtccatgg tcggcaccag
    17401 gttggtcacc agttccgcca tttttacttc catttcggtt ggcgcgccga agcttaaacc
    17461 gcgctccgca gcttcgatca ccgcattgcg gatagccgga tggttatgcc ccagtaccat
    17521 tggcccccag gaaccgacat agtcgatata tgctttgcca tcgacatcgt acagatacgc
    17581 gccgtccgct ttttcgataa acagcggggt gccgcccacg ccagtgaagg cgcgaacagg
    17641 ggagttcacg ccgccgggga tcagctcgcg ggccgcgcta tagagatttt cagacttact
    17701 catggaaaga ttcctggttc gtagaaaaag tgaatacccg ctattctaag ttattcagag
    17761 aaggttatga aagttttacg catttgaaac aatacgattt gcaggggatt ttcacggcgt
    17821 tggcgagtag aatgccgact ttagatttgt attaccaatt aatgatcttc tgatgaaaac
    17881 agacacttcc acctttttag ctcagcaaat tgtgcgctta cggcgcagag atcagattcg
    17941 tcggttaatg cagcgggata aaacgccgct ggccatcctg ttcatggcgg ccgttgtcgg
    18001 cacgcttacc ggactggttg gcgtcgcctt tgaaaagacg gtttcctggg tacaaaacat
    18061 gcgcattggc gcgctggttc aggtcgcgga ccatgcgttt ttgctttggc cgctggcctt
    18121 tatcctttcg gcgttactgg cgatggtcgg ctattttttg gtgcgaaaat ttgcgccgga
    18181 agccggcggc tcgggtatcc cggaaattga aggcgcgctg gaggagttac gtccggtgcg
    18241 ctggtggcgc gtgttgccgg tgaagtttat cggcgggatg ggaacgttgg gcgcaggaat
    18301 ggtattaggg cgcgaagggc caacggtgca aatcgggggc aacctggggc gcatggtgct
    18361 ggatgttttt cgtatgcgca gcgccgaagc gcggcatacg ttgctggcga ccggcgcggc
    18421 ggcggggctc tctgcggcgt ttaacgcgcc gctggcgggt atcctgttta ttattgaaga
    18481 gatgcgcccg cagtttcgct acaacctgat ttcgattaaa gcggtgttta ccggcgtcat
    18541 catgtcgagc attgtgttcc gcatatttaa cggcgaagcg ccgattattg aagtcggcaa
    18601 actgtctgat gcgccggtta acacgctgtg gttatacctt atcctcggta ttatttttgg
    18661 ctgcgtcggg ccggtattta attcgttggt gctgcgtacc caggatatgt ttcagcgctt
    18721 tcatggcggc gaaattaaaa aatgggtgct tatgggcggc gcgatcggcg gcctgtgcgg
    18781 tattctgggg ttgattgagc cggcagcggc aggcggcgga tttaacctta ttcctatcgc
    18841 cgcggcaggt aattttagcg tcgggctact gctgttcatc tttattaccc gggttgtcac
    18901 gacgctgctt tgcttttctt ccggcgcgcc ggggggcatt ttcgccccga tgctggccct
    18961 gggaacgctg cttggtacgg ccttcggtat ggcggcggca gtgcttttcc cgcagtatca
    19021 cctggaggcc ggtacctttg cgattgccgg gatgggggcg ctgatggcgg cgtcggtgcg
    19081 cgccccgttg acggggattg tgctggtgct ggagatgacc gataactatc agctcatttt
    19141 gccaatgatt atcacctgtc ttggcgcgac actattagcc cagtttttgg gcgggaaacc
    19201 gttatactca accatcctgg cgcgcactct ggcgaagcag gatgcggaac aggcggcgaa
    19261 aaaccagaat gcgcctgcgg gcgagaatac ttgaacgaat taccagggta ttagataatg
    19321 actgccaata ttgggtgaaa atttatccaa ttaccgatgt cgtttggagc aaaatatgag
    19381 tgatgacgta gcgctgccgc tgcagtttac cgacgcagca gcgaataaag taaaaagtct
    19441 tatcgctgac gaagataacc cgaatctgaa actgcgcgtg tatatcaccg gcggtggttg
    19501 cagcggcttc cagtatggtt ttacctttga cgatcaggtt aacgaagggg atatgaccat
    19561 cgaaaaacag ggcgttggcc tggtggttga cccgatgagt ttgcagtatc tggtgggtgg
    19621 ttcggtagat tataccgaag gtctggaagg ttcccgcttc attgtaacca acccgaatgc
    19681 gaaaagtacc tgcgggtgtg gctcttcctt cagcatttga ttgctgttcg ttgtgccgga
    19741 tggcgacgcg agcgtcttat ccggcctaca ggaaagatgt tctaggcccg ataagcgtag
    19801 cgccatcggg caaaacaata tcaacgtccg ttttcatcca gggcaaacgt cggcaatttc
    19861 aaatgccagc gaatggccgc cagccgaata aacagcgtga cgaccatgcc catcatgcta
    19921 gcgctttcca gcggtactga aaacgtataa aacgcggtgg cgtgaacaat cccgccgata
    19981 atacaggccg tggcatagat ttcggtgcgt aggatcatgg ggatctcgcg tgccagaaca
    20041 tcgcgaataa tcccgccgcc gacgccggta atcacgccca tacagacggc cactaatggc
    20101 cccgtttcag cgaggaaggc tttattcacc ccaatgccga caaacaccgc cagcccgacc
    20161 gcatccagta ccggcaacat ccatttcggc agacgtctcg gctggcgaac cagcaggatg
    20221 gtcagcatac tggtgaccat ggcgacgacc aggtcggtag gatctttaac ccagaatacc
    20281 gggccgttat ccagcgccat atcgcggatt gtcccgccgc cgacggcagt aacgacgccg
    20341 agcaccagga cgccgaacgg gtccatacgt aatttcccgg ccagcaacac gccagagata
    20401 gcaaatacag ccgtgcctac aatatccagc caatagacga gcattgtcga atccccacta
    20461 ggagcctggt aagacaggct ctaattcacc tgtgaaagcg cattacagag ttgttttgcg
    20521 gcgaggataa tacgcgggct tgcgcgttca aaccagtcgc tgttaagcgg aataaccgga
    20581 atttttaaca ggtttcccca gtattgttca attttgagaa tttcgcccgc ttttccggcc
    20641 acgataatgg cctggggatg ccttgccagc acctgctcac ggctgacttg cggccacggc
    20701 acgcggctgt cagcaaagac gttttctccg ccgcaggtcg tcaaaacctg atgttgaata
    20761 gaccctttac cactggtaaa cagaggattc atgccaaact gaagaaagac gcgcttttta
    20821 gctttaccgg catactcgac tttgagcgcg gcgtactctt ttagcaatgt ctgcgctgcc
    20881 tgctgagcct tttccggctg cgggctccag gcggccagtt ggcggagcgc gtcggcgatc
    20941 tgttcgatgg ttaccgcgtc cacccacatg accttaatac ctaatgacgt cagttggttt
    21001 acctggcgtt ccgcattacc gccgcgccag gcgacgacca gatccggctt cagcgccaca
    21061 atgcgctcca gattcattcc ctgccaggta gagacctgtt ctattttttg cgcttcgggc
    21121 gggtagtcgg aatagctgct gacgccaacg ggcgtaatct cggcggcaaa agcaagctcc
    21181 gtattggcgg gagagagcgt aattacgcgc ggcgcagcgt aaagccacac cgggagcgta
    21241 agcagcaggg cgcccagcgc cctgaacatt tgcttagcca tgcgccagtt tctgtaccag
    21301 cgtttcgacc atcagagtcg actgtttcgc cgccaccgcg aggaattcgt caaagctgag
    21361 gtgcgattgc tgatcggcca cgtcagagat agcgcgtacc accacgaacg gcacgttgaa
    21421 gttatggcag acgtgggcga tagcggtggc ttccatctct acggcgaccg cgtcggggaa
    21481 gttatgccgg attttcgcca gcccgacgga accgttaata aacgcgtcgc cgctaacaat
    21541 aaggccgcgt accgcgttca gattcaactc cctgatgcag gattccgcgg cggcgatcag
    21601 cttatcatcg gccttaaatc cggccggaca gcccggtaat tgcccgtatt catagccgaa
    21661 agcggtcaca tcagcgtcgt ggtaacgcgc ttcgtcagag acgacgatat cgccgacctt
    21721 cagcgtggac gccagaccgc ctgcggaacc ggtattgatg atcacgtccg gcttgcagtg
    21781 ctccagaagc aacgttgcgc ccagcgccgc cgcgacttta ccgataccgg atttcagcaa
    21841 cgccacttcg gtgccgttca actggccagt gtaaatttcg cagccgccca gcgtaatcgt
    21901 ctgacggttg tcaattttgt cacgcagcag cgtaacttct tcttccattg cgccaatgat
    21961 gccgattttc atagatttac tcgcgataag tcagttttgg gggcatagtt tatcatgcgc
    22021 ttatggggaa gcgcatttct caggcgggga gaggatatgg catcgatcga tttccgaaat
    22081 aaaattaact ggcatcgtcg ttatcgttca ccgcagggcg taaagacgga acatgagatc
    22141 ctgcggattt ttgaaagcga tcgcgggcgg attatcaact ctccggctat acgccgtttg
    22201 cagcaaaaaa cgcaggtttt cccgctggag cgcaatgccg cggtgcgtac tcgtctgacg
    22261 cattcgatgg aggtgcagca ggtggggcgt tatatcgcga aagagatttt aagccgcctg
    22321 aaagagcaaa accgactgga ggagtacggt ctggatgcgc tgaccggtcc ctttgaaagt
    22381 attgtggaaa tggcctgtct gatgcacgac atcggtaatc cgccgttcgg tcattttggc
    22441 gaggcggcga tcaatgactg gtttcgtcag cggctgcatc cggaagatgc ggaaagccag
    22501 ccgctcacgc atgatcgctg tgtggtttcc tcgctacggt tacaggaagg tgaagaaaat
    22561 ctgaacgata ttcgccgcaa agtacgtcag gatatctgcc attttgaagg taatgcacag
    22621 ggaattcgtc tggtacatac gctcatgcgg atgaatctta cctgggcgca ggttggcgga
    22681 attttaaaat atacccgtcc ggcatggtgg cgagggccgg tgccggattc ccatcgctat
    22741 ttaatgaaga aaccgggcta ttatctttct gaagagaagt atattgcgag gttacgtaaa
    22801 gaacttcagt tagcgcctta cagtcgcttt ccattaacgt ggattatgga agccgcagat
    22861 gatatttctt attgtgtcgc cgatcttgaa gacgcggtag agaaaagaat ctttagcgtt
    22921 gagcagcttt atcaccattt atatcacgcg tggggccacc atgagaagga ttcgctgttt
    22981 gagctggtgg taggaaatgc gtgggaaaaa tcacgcgcca atacattaag ccgcagtacc
    23041 gaagatcagt tttttatgta tttacgggta aatacattaa ataaactggt gccctatgcc
    23101 gctcagcgtt ttattgataa tttgccgcag atttttgccg gtaccttcaa tcaggcgtta
    23161 ctggaagatg ccagcggttt tagccgcctg cttgaactct ataagaatgt ggcggttgaa
    23221 catgtgttta gccatccgga tgtagaacag cttgaactac agggataccg ggtgatcagc
    23281 gggttattag atatctatca gccgctatta agcttgtcgc ttaacgactt tcgcgagctg
    23341 gtggaaaaag aacggttgaa acgcttccct atagaatcgc gcttatttca gaaactttct
    23401 acgcgccatc gtttggccta cgtggaagtc gtcagtaaat tacccacgga ttcggcggag
    23461 tacccggtac tggaatatta ttatcgctgt cggttgattc aggattatat cagcgggatg
    23521 actgaccttt acgcatggga tgaatatcgg cgtttgatgg cggtcgaaca gtaaatggac
    23581 ttttgtaaag atggacaata aatttttact ttttccagaa actttattcc ggaacttcgc
    23641 gttataaaat gaatctgacg tacacagcaa ttttgcgtta cctgttaatc gagattgaaa
    23701 cacatgaaaa aaaccacatt agcaatgagt gcactggctc tgagtttagg tttggcattg
    23761 tcgcctctgt ctgccacggc ggctgaaacg tcctcttcag caatgactgc ccagcagatg
    23821 ccaagcctgg caccgatgct cgaaaaagtg atgccatcgg tggtcagtat taatgtagaa
    23881 ggtagcacca cggtgaatac gccgcgtatg ccgcgtaatt tccagcaatt ctttggcgat
    23941 gactccccgt tctgccagga cggttctccg ttccagaatt ctccgttctg ccagggcggc
    24001 ggtaacggcg gcaacggcgg tcaacaacag aaattcatgg cgctgggctc cggcgtaatt
    24061 attgacgccg cgaagggcta cgtcgtcacc aacaaccacg tggttgataa cgccagcgtg
    24121 attaaagtac agcttagcga tgggcgtaaa ttcgatgcta aagtggtggg caaagatccg
    24181 cgttctgata tcgcgctgat tcaaattcag aatccgaaga acctgacggc gattaagctg
    24241 gcggactccg acgcgctgcg cgtgggggat tataccgtcg ctattggtaa cccgtttggt
    24301 ctgggcgaaa cggtgacgtc aggtatcgtt tcggcgctgg ggcgtagcgg cctgaacgta
    24361 gaaaattacg agaactttat tcagaccgac gccgcgatta accgcggtaa ctccggcggc
    24421 gcgctggtga acctgaacgg tgagctgatc ggtattaaca ccgcgattct ggcgccggac
    24481 ggcggcaaca tcggtatcgg cttcgctatc cccagtaaca tggtgaaaaa cctgacgtcg
    24541 cagatggtgg aatacggcca ggtgaaacgc ggcgaactgg ggatcatggg gactgagctg
    24601 agctctgagc tggcgaaagc gatgaaagtc gacgcccagc gtggcgcgtt cgtcagccag
    24661 gtgatgccga attcgtccgc agcgaaagcg ggtatcaaag ccggggatgt cattacctcg
    24721 ctgaacggta aaccgatcag cagctttgcg gcgctgcgcg ctcaggtcgg cactatgccg
    24781 gtcggcagca aaatcagcct cggtctgctg cgtgaaggta aagcgattac ggttaatctg
    24841 gaactgcagc agagcagcca gagtcaggtt gattccagca ccatcttcag cgggattgag
    24901 ggcgctgaaa tgagtaataa aggccaggat aaaggcgttg tggtgagcag cgtgaaagcg
    24961 aactcacccg ccgcgcaaat tggcctcaaa aaaggcgatg tgattatcgg cgctaaccag
    25021 cagccggtga aaaatatcgc cgagctgcgt aagattctcg acagcaagcc gtcggtgctg
    25081 gcgctgaata ttcagcgtgg tgatagttct atttatttgc tgatgcagta atcacctttg
    25141 tcccccttcc accacggaag ggggcaacac ttttctgtga aactccccac aactccatac
    25201 ttctttgcac cgttttgtgc atttgcacaa tgtcgaggcc tgtcatcttc cttatgcttg
    25261 tgctctgctc acaggaggga tttatggctg gctggcatct tgataccaaa atggcgcagg
    25321 atatcgtggc gcgcactatg cgcatcatcg ataccaatat caacgtaatg gatgcccgcg
    25381 ggcgtattat cggcagcggc gatcgggaac gtattggtga attgcacgaa ggcgcgttgt
    25441 tagtgctgtc acagggccgg gttgtggata tcgacaacgc cgtggcgcga cacctgcacg
    25501 gggtgcgtca ggggattaat cttcccttac gccttgaggg cgaaattgtt ggcgtgatcg
    25561 gtctcaccgg cgaaccagag catctgcgta aatatggcga actggtgtgt atgactgccg
    25621 aaatgatgct ggaacagtcg cggttaatgc accttttggc gcaggatagc cgtttgcgtg
    25681 aagagctggt gatgaacctg attcaggccg aagaaaatac gccggcgctg gtggaatggg
    25741 cacagcgttt agggatcgat ttgaaccagc cgcgtgtggc ggcggtggtg gaagtcgaca
    25801 gcggccagct tggcgtcgat agcgcaatgg cggaacttca gcagttgcag aatgcgctta
    25861 ccacgccgga gcgtaacaac ctgatagcca ttgtttccct taccgagatg gtggtgctca
    25921 aacccgcctt aaactcgttt ggtcgttggg atgctgaaga tcatcgtaag cgcgtagagc
    25981 agcttatctc gcgaatgaaa gagaatggtc agctacgttt tcgcgtggcg ctgggtaatt
    26041 actttaccgg accgggcagt attgcacgct cataccgcac ggcgcgcacc acgatgatgg
    26101 tcggcaaaca gcggatgcca gaaagccgca gctattttta tcaggatttg atgctgccgg
    26161 tcctgttaga tagcctgcgt ggcggctggc aggccaatga gctggcgcgc ccgctggtaa
    26221 aactcaaagc gatggataac aacgggttat tacgtcggac actgacggcg tggtttcgcc
    26281 ataatgtcca gccgctggcg acctctaagg cgctgtttat tcatcgtaat acgctggaat
    26341 atcggctaaa tcgtatttcg gaactgaccg ggctggattt gggaaatttt gacgatcggc
    26401 tgttgctgta tgtggcgcta caattggatg aacagcgtta agcccggcgg cgcttcgctt
    26461 accaggccta cggggatata cctgtaggcc ggataaggcg taacacgtcg ccatccggca
    26521 acacacagct tacttacggg taagcttgtc cagatcggct tcgatttcac tgatcttatt
    26581 cgcgacgacg ctttccagat ggcgcaagtc gtcgaggatc ttacgtttga gatcgagttc
    26641 tgagcggtcg cgctggcaga tttggtccag ctcgtcaatc acatagcgta ggttagggct
    26701 aatctcctgt acttctttat aaccctgacc gatgccatca gccaccaccg ttttacgctg
    26761 gcgtggatac ttaaacttca cgcttttagc aaagaattca cctctatcct tttgaaaata
    26821 gattttcagg atatcgttat tggcttcttg ccgcaggctg taacgatcga tttcctcagg
    26881 attggtaatg cccagacttt ttagattgtc atacatagcg gtatccttca tcacactata
    26941 acttttgaat aattaacgaa aaattggttt ttcgccacca atggatacaa aaaaagcgcg
    27001 gttgatcgca gaagacgtct cggcaacgtc atgagcaaaa gggcggcggt tattgatagc
    27061 ttaagtaatt caacgcgata ttccgtttat agagaaagcg tttgaggtca gtgtgggaaa
    27121 ttgaccggag gcagtggtcg ataaccttga gaggcggaat ctatgtccgg aacgtataat
    27181 gccactattc gccgggtggt gatttccgcc tggataggaa actccattga atattatgat
    27241 tttctattat acggcttagc aagcgcgctg gtatttggcc cgcttttttt cccctggcgc
    27301 cagcccattg actgcaacgt tatcttcttt tgccagtttc ggcgtgggat ttatttcccg
    27361 accgctgggc gcgctatttt ttggcaacag gggggatacg cttgggcgta aaaacacgtt
    27421 attaatcacg ttaggcggga tgggcgcggt cacgtttctc atcggttgcc tgccttctta
    27481 cgccagtatc ggcgcgctga cacctgcttt actggttatt ctacgttttc tacagggatt
    27541 tatggttgga ggtgaatggg gaggcgccat gttgatggtc gtggaatatg ctgctggaaa
    27601 gcaccggggg cggttaagcg cgctatcgca aacaggagga ctcacgggac aattattggc
    27661 gacaggcgta tttatagtcg tgacccaatt accgcaggag gcgttgttat cgtggggatg
    27721 gcgtattcct tttctgctca gtgcgctttt ggtgttgccg ggattatata tgcgtcatcg
    27781 tctggatgag acgcctgtct tccgtgcgtt taaaaagcag caggccatta atcataggca
    27841 gcaaagggat gaaaggccgg tggtcaaagt agtacgagaa caatggcgta gcattttgct
    27901 gattataatt ctgcgttttg cggaaagcgt tccctttttt cttgctaccg tcttcgcggt
    27961 ttcctgggcg acgacgcagc ttgggattgc cagcctgact attctgtaca ttgtaatgtt
    28021 cacctgtctg ctggcgtatc ccatgcacgt gctatttggc atcatgtcgg atcggcgtgg
    28081 ctgccgtcag gtgtatattt tcggcgcgct ttttgtcgcg gcaatggctt ttcccttttt
    28141 ctggctgctg gaaagccgtt cgctcatact gatgacaatg ggctacgttc tgcttattaa
    28201 cattggtcat aattcactga atgccgtgca accttctttt ttcgccggac tgtttcatcc
    28261 gcctgtacgc tacagcggtt catcaattgg cgctcagttg ggggcggttg tggcaggggg
    28321 attcacgccg tttatcgcta aagcgttaag cgcagtctat gataacagtt ggactttggt
    28381 tgccggttat gtcgttttga ctgcgctggc ttcggcgttt gcggcaaaga ttgcgccgga
    28441 caccgtgtta ccgcattcgc cgtaatgcaa aggggggctg tcgcccccgc ttttcactcg
    28501 cttaatcaat cgtgcgcaat aattcgttaa tgcccacttt accacgcgtt ttggcgtcga
    28561 cttttttcac gatcaccgcg cagtacaaac tgtacttacc gtcttttgac ggcaggttgc
    28621 cggaaacgac cacggagccc gccggtacgc ggccatagtg aacttcaccg gtttcgcgat
    28681 cgtagatttt ggtgctctgg ccgaggtata cgcccatgga aatgacggaa ccttcttcga
    28741 caatgacgcc ttccacgact tcagaacgcg cgccaataaa gcagttgtct tcaatgatgg
    28801 tcgggttagc ctgcagcggc tccagtacgc cgccgatacc cacgccgccg gaaaggtgaa
    28861 catttttacc aatctgcgca caggaaccca ccgtcgccca ggtgtcaacc atggtgcctt
    28921 cgtcaacgta ggcgccgatg ttaacgtaag acggcatcag cacggtgttg cgggcgataa
    28981 atgcgccctg acgaacggcc gcaggcggaa cgacgcggaa gccttctttc tgaaaacgcg
    29041 cttcgtcgta atcagcgaat ttcatcgggg ctttatcgaa gtagcggctt tccgcaccgt
    29101 cgataacctg gttatcgtta atacggaaag agagcagaac cgctttcttc aaccactggt
    29161 gagtgaccca ctgaccgtcg attttttctg cgacacgcag cgcgccggaa tcaagtagag
    29221 aaatgacctg ttttaccgcc tctcgggtca cggtatctac attagccggc gtaatatcgg
    29281 cgcggcgctc aaaagcggtc tcaataacgt tctgtaactg ctgcattgtt aaactctttc
    29341 atataaataa acacactacc ctttatcgtt tggattgagg gccgctgtca accgttgttg
    29401 cacctcaagt tgcagcacat tattaagtgc gcgccgatcc gctgtggcga ttatgaataa
    29461 atcttctact cgttcaccaa tggttgtaat tcgggcacca tgaagcgaaa ttcccagatc
    29521 ggcaaaaatt tgtccgaccc tggccagcag accaggttga tcgagcgcga tcaattccat
    29581 gaatgatttt ctgtcggtat gggtgggcag aaaattgact tccgtttcga ccgtaaagtg
    29641 ccgtaacttt gccggttgcc gacgcggctg cggcggctgc cagctatgct gcgtaatggt
    29701 ctgttcaaga ccggtgcgaa taacgtcatg gcgatctgcc gccagcgggc tgccgtctgg
    29761 ttccagaacg ataaacgtat ccattgccat gccgtcgcga gtggtaaaga tctgcgcgtc
    29821 atggacgctt aaattacgcc tgtccagctc ggcgcagacg gcggcaaaca gatagggtct
    29881 gtccggactc cagataaaaa tttcggttcc gccgcgcgtg gcttgcggac tgagcaacac
    29941 taacggttgg ctcagatcgt gctgcaataa atggcgtgcg tgccaggcga gctgatttgg
    30001 actatgacga acaaaatagt tagcgcgaca gcgggtccag attttgtgca gcgcggcttc
    30061 atcaatattg tccattcgca gcagcgccag cgcctgaagc tgatggtgac gcacgcgctc
    30121 acgcatatcc ggcgtatttt gcattccacg cctgagctgt ttttcagtgg cgaagtacag
    30181 ctcgcgcagc aggctctgtt tccagctatt ccacaaggtt tcgttggtcg cgcagatgtc
    30241 cgcgacggtc aggcagacca gaaaacgcag ccgtgtttcg gtttgcacct cttcggcaaa
    30301 ctgcttgatg acttccggat cctggatgtc gcggcgctga gcggtgactg acattagcag
    30361 gtgttggcgc accagccagg cgaccagttg cgtttcgcgt gagttcaaac cgtgcagttc
    30421 ggcgaaggtg agtacatcct gcgcgcccag taccgaatgg tcgccgccgc gtcctttcgc
    30481 aatatcgtgg aacagcgcgg cgatcaggat cagttccgga tggggaagcc gcggccagag
    30541 atcgacgcat agcggatggc gctggcgtgt ctcttctttc gcaaagctct ccagtttgag
    30601 cattacgcgg atggtgtgtt catccaccgt gtatgcgtgg aacaggtcaa actgcatttg
    30661 tccgacgatg tgcgaccact gcggcatata agcccacagt acgctgtggc gatgcatggg
    30721 cagcaggccg cggctgaccg cgccgggatg gcgtagcata ctcagaaaca gagtgcgcgc
    30781 ctccgggatg taacacagcg gttggctcag gtggcggcgg gcgtggcgca agtggcgtaa
    30841 cgtcgtagag tagatgccgg tgatcgcgct attgcgcacc atcatataaa acatccgcag
    30901 gatcgcttgc ggttcgcgga taaacagcgt gtcgtcacgc agatcaatga gcgtgccgcg
    30961 cagttgaaac tcatcgtcaa caggacgtgg tttttcatcc gcaggcagcg ccagaatcgc
    31021 ctcgtcaaat agctgaagca gcatctgatt aagttcgctc acccgacgcg taacccggaa
    31081 gtagtctttc atcatccgct caaccggatc attgccctcg ccgctgtagt taaggcgttg
    31141 agcgacgctt aactggcggt cgaacagcag gcggttatcg tagcggctga ccaccagatg
    31201 tagcgcaaag cgaatgcgcc acaggatatg caggcactcg ttgagctccg cgcactcagc
    31261 cggggttaaa aagccgaatc ccaccatctc atcgagcgag gtggcgccga agtgacgtcg
    31321 ggcgacccac tgcaatgtat ggatatcgcg caggccgccg gggctgcttt taatatccgg
    31381 ctccagatta tagctggtac cgtgatagcg ctggtggcgc tggttctgct cttctacttt
    31441 ggcggcgtaa aatttgtcgg acggccaaaa accttcgctg aaaatatgtt tttgtagtgc
    31501 cagaaacaga gcgacatcac cgatcagcag gcgcgtttcg atgaggtttg ttgcaacggt
    31561 taaatcagac agaccttcca gcagacactc ttccagcgta cgtacgctat gcccgacatc
    31621 cagcttgacg tcccaaagta aagtcagcag ctcgccgacc ttttgcgcct gttcatcggg
    31681 cagctttttg cggcttaaaa tgagcagatc aatatcggaa agcggatgca gttcgccgcg
    31741 tccatagccg ccgacggcga ccagcgccag atcggcaatc tgaccgaaac cggcctcaat
    31801 ccacaggcgt tgcaacaact ggtcgataaa ttcggttcgg gcttcaataa gctgttcagc
    31861 acaaatgccg ctgtcaaatg cctctcccag ccagtgttga aagatgtcga tgcgggcttt
    31921 gataccggcg acggtcagtt cagcgcgcgg ccagacgcca gggttttgcg gctggtcagg
    31981 gagggtgggg agtgcggtat tcgcgtgctg ttcaggaaga gtattcatat gcgccaccca
    32041 ttaaaaagcc ggatggtggc gtgaacgcct tatccggcct acgaagtagt acaatttgta
    32101 ggcctgataa gatgcgaagg catcgccatc aggcaaaaca ttattcgtcg tgtgtgatga
    32161 tcgccgggat ggtgtcatct ttacgcagcg tcagaatttc acagccgttt tccgttacca
    32221 caatagtatg ctcgtactga gcagacaagc tgcggtcttt ggtttttacc gtccagccgt
    32281 ctttcatggt gcggatacgg taatccccgg cattcagcat cggttcaatg gtaaaggtca
    32341 tgccaggctg caacacgacg ccaccatcgt ctgcatcata atgcagcacc tgcggttctt
    32401 catggaagcc gcgaccaata ccgtgtccgc agtattcacg taccacggag aaaccttcgc
    32461 cttcggcata tttctggatg gcggcgccaa tggtgcgcag gcggatgccc ggtttcacca
    32521 ttttgatgcc cagatacagg ctctcttgcg tgacgcggca cagacgctcg cccagaatag
    32581 tcggtttgcc gacgataaac atctttgagg tatcgccgtg gaattcatct ttaatcacgg
    32641 tcacgtcgat gttgacgata tcaccatctt tcagatgttt agcgtcatcc ggaatgccgt
    32701 ggcacaccac ttcattaata gagatacaga cggatttcgg atagccgtgg tagccgaggc
    32761 aggcggagat cgcgtgttgt tcgttaacga tgtaatcgtt acagatacgg tccagttcgc
    32821 cggtggtgac gcccggtttg atatacggtt cgatcatttc cagcacttcg gctgccagac
    32881 ggcccgcgac gcgcattttt tcgatgtctt cagatgtctt gatagagata gccatgaatt
    32941 ctgtccatca gtgccgatga tttcggcaat aattgtgtaa gtgctgacaa tggtatcagt
    33001 caggggtgta ccctgccaaa ttgagaatca ttctgaactt cgcctttcgt gccacaggtg
    33061 cgttggcgac attttttcac cccagtcact tactggccgt aagctcccgg ggatgcaaaa
    33121 atttgccgcc tgcctgtaac acgaaattca tcgttcaatt cagcactgag tgccaacaat
    33181 tattggtgtc ggtggcgtat ttgtggtata aagcgtgccg gacttccgat ccattcgaag
    33241 actacacacg atggacggga gcgacaaatc tcactttgtg taacaacaca cacgtatcgg
    33301 cacatattcc ggggtgccct ttggggtcgg taatatggga tacgtggagg cataacccca
    33361 acttatctat agaggtttta aatcatggca actgtttcca tgcgcgacat gctcaaggct
    33421 ggtgttcact ttggtcacca gacccgttac tggaacccga aaatgaagcc tttcatcttc
    33481 ggcgcgcgta acaaagttca catcatcaac cttgagaaaa ctgtaccgat gttcaacgaa
    33541 gctctggctg aactgaacaa gatctctgct cgtaaaggta aaatcctttt cgttggtact
    33601 aaacgcgctg caagcgaagc ggtgaaagaa gctgctaaca gctgcgacca gttcttcgtg
    33661 aaccatcgct ggctgggcgg tatgctgact aactggaaaa cagttcgtca gtccatcaaa
    33721 cgtctgaaag acctggaaac tcagtctcag gacggtactt tcgaaaagct gaccaagaaa
    33781 gaagcgctga tgcgtactcg tgagcttgag aaactggaaa acagcctggg cggtatcaaa
    33841 gacatgggcg gtctgccgga cgctctgttc gttatcgatg ctgaccacga gcacattgct
    33901 atcaaagaag cgaacaacct gggtatcccg gtatttgcta tcgttgatac caactctgat
    33961 ccggacggcg ttgacttcgt tatcccgggt aacgatgacg caatccgtgc tgttagcctg
    34021 tacctgggcg ctgtcgctgc aaccgttcgt gaaggccgtt ctcaggatct ggcttcccag
    34081 gcggaagaaa gcttcgtaga agccgagtaa taaggcttga taactcccta aaatagttcg
    34141 agttgcagga aggcggcaag ctcgagaatt cccgggcgct tacatcagta agtgtccggg
    34201 atgagcgagt gaaggcaacg cgcctgcggc tcgaaatatg aaggggagag cccttataga
    34261 ccaggtagta tcacgtttgg ttagggggcc tgtatatggc cccctttttc acttttatat
    34321 ctgtgcggtt tgatgccggg cagatcaaat ctttcgagga ttttagaatg gctgaaatta
    34381 ccgcatccct ggtaaaagag ctgcgtgagc gtaccggcgc aggcatgatg gattgcaaaa
    34441 aagcgctgac tgaagcgaat ggcgacattg agctggcaat cgaaaacatg cgtaagtccg
    34501 gcgctatcaa agcggcgaaa aaagcaggca acgtggctgc tgacggcgta atcaaaacca
    34561 aaatcgacgg taacgtcgct ttcattctgg aagttaactg ccagactgac ttcgtggcta
    34621 aagatgctgg cttccaagca tttgctgaca aagtgctgga cgccgctgtt gctggcaaaa
    34681 tcactgacgt agaagtcctg aaagcgcagt tcgaagaaga gcgcgttgct ctggttgcga
    34741 aaatcggcga gaacatcaac attcgtcgcg tcgcttccct ggaaggcgac gtgctgggtt
    34801 cttaccagca cggtgcgcgc atcggcgttc tggttgccgc taaaggcgct gacgaagagc
    34861 tggttaagca gctggcgatg cacgttgcgg caagcaagcc ggaattcgtt aagccggaag
    34921 acgtgtctgc tgacgtggta gagaaagagt accaggtaca gctggacatc gcgatgcagt
    34981 ccggtaagcc gaaagaaatc gcagagaaaa tggttgaagg ccgcatgaag aaattcaccg
    35041 gcgaagtttc tctgactggt cagcctttcg tcatggaacc gagcaaatct gttggccaac
    35101 tgctgaaaga gcacaacgct gacgtgactg gcttcatccg ctttgaagtg ggcgaaggca
    35161 ttgagaaagt cgagactgac tttgcagcag aagttgctgc gatgtctaag cagtcctgat
    35221 tttcctgagg agccgcctga gggcggcttc tttttgcgcc tctcttgtaa aatcagccga
    35281 cgcctggcgt ctgcgctgaa atgcgacgta caatgtcgcc ggaattaact catatcaatc
    35341 gttgacagtc tcaggaaaga aacatggcta ccaatgcaaa acccgtctat aaacgcattc
    35401 tgcttaaatt aagcggcgaa gctctgcagg gtacggaagg cttcggtatt gatgcaagca
    35461 tactggatcg tatggctcag gaaatcaaag aactggttga actgggtatt caggttggtg
    35521 tggtgattgg cggtggtaac ctgttccgtg gcgcgggtct ggcaaaagcg gggatgaacc
    35581 gcgttgtggg cgaccacatg ggcatgttgg ccaccgtcat gaacggcctg gcaatgcgtg
    35641 atgcgcttca ccgcgcctat gtgaacgccc gcctgatgtc ggcaattcct ttaaacggcg
    35701 tgtgcgacaa ctacagttgg gccgaggcta ttagcctgct gcgtaataac cgtgttgtga
    35761 ttctgtctgc aggtacgggt aacccgttct tcactaccga ctctgcggcc tgtctgcgcg
    35821 ggatcgaaat tgaagcggat gtcgtactga aagcgaccaa agtggatggt gtattcactg
    35881 ccgatccggc aaaagatcct tccgcgacca tgtacgatca gctgacctac agcgaagtgc
    35941 tggataaaga gctgaaagtg atggatctgg cggcgttcac gctggctcgt gaccacaaac
    36001 tgccgattcg tgttttcaac atgaacaaac cgggcgcgct gcgtcgtgtg gtgatgggcg
    36061 aaaaagaagg gacgttaatc acggaataat tcccgtgagc gccaaatacg ggtaagattc
    36121 tgttctattg acgggtctta ttacctggca gaaattaaac gagactatac ttagcacatc
    36181 tttatattgt gtgaccgtct ggtctgactg agactagttt tcaaggattc gtaacgtgat
    36241 tagcgatatc agaaaagatg ctgaagtacg catggaaaaa tgcgttgaag cgttcaaaac
    36301 ccaaatcagc aaagtgcgca cgggtcgtgc ttctcccagc ctgctggatg gtattgtcgt
    36361 agaatactat ggcactccga ccccgctgcg ccagttggca agcgtaacgg tagaagactc
    36421 ccgtacctta aaaattaacg tgtttgaccg ttctatgggg ccagccgttg aaaaagcgat
    36481 catggcgtca gacctcggtt tgaatccaag ctctgcgggc accgatattc gcgttccgct
    36541 gccgccgctg accgaagaac gtcgtaaaga tctgacgaaa attgtccgtg gagaagcgga
    36601 gcaggcgcgt gtcgccgtac gtaacgtccg ccgtgatgcg aacgataaag taaaagctct
    36661 gctgaaagat aaagcgatca gtgaagatga cgatcgtcgc tctcaggaag aagtacagaa
    36721 aatgaccgac gcggcaatta agaaagtgga tgcggcgttg gcagataaag aagcagaact
    36781 gatgcagttc tgattgatct gtacgcagat ataaactcat tccaccgcta aacctggcgg
    36841 atgagtggtg tacaaagcgc cgcgcagaag acattatcag gtctcctgtg cggcgttttg
    36901 ctttttattc cgtttcaaca cttctggacg tttcatgaag caattaacca ttctgggctc
    36961 gaccggctct attggttgca gcacactgga cgtggtgcac cataatcctg atagctttcg
    37021 cgttatcgcg ctggtggcgg gtaaaaatgt cgcccgcatg gcggagcagt gcctggagtt
    37081 ctcgccgcgt tatgccgtga tggacgatac gtcgagcgca gaacagctca aaataatgct
    37141 tcagcagcat ggcagccgca ccgaggttct gagcggtcag caggctgcct gtgagatggc
    37201 ggcgcttgat gaggttgggc atgtgatggc ggccattgtg ggcgcggctg gtttactgcc
    37261 gaccttggcg gcgatccgcg cagggaagac gattctgctg gcgaataaag aatcgctggt
    37321 gacctgcggg cggctgttta tggacgaagt gaaacgcagc aacgcccggc ttttacccgt
    37381 cgatagcgaa cataacgcga tttttcagag tttgccgcaa tctattcagc ataatctggg
    37441 atacgctgac cttgagcaaa atggcgtaac gtcgattttg cttaccgggt ctggtggccc
    37501 gtttcgtgaa acgcccatgt gcgatctggc agcgatgacg ccggatcagg catgtcgtca
    37561 tccgaactgg tcgatggggc gaaaaatctc cgtcgactcc gccaccatga tgaataaagg
    37621 tctggaatac attgaagcgc gttggttatt taatgccagc gcacgtcaga tggaagtgtt
    37681 gatccatccg caatcggtca ttcattcgat ggtgcgttat caggacggca gcgtcctggc
    37741 gcagcttgga gaacctgaca tgcgtacgcc tattgcgcat acgatggcat ggccgaatcg
    37801 cgtcacgtcc ggcgcgcagc cgctcgattt ttgcaaactc agcgcgctga cgtttagcgc
    37861 gccagattat cagcgttatc cttgcctgaa gctggcgatg gaggcgtttg agcaaggtca
    37921 ggcggcaacg acggcgctca atgcggcaaa cgaaatcacc gttgccgcgt ttctggcgca
    37981 acagattcgt tttaccgata tcgccgggct caatttagcg gtgctggaga ggatggattt
    38041 acacgaaccg gcaagcgttg atgacgtatt gcaggttgac gccatcgcgc gtgaagtagc
    38101 cagaaaacaa gtgatacggc tctcacgctg acgattatcc cgcgacagaa gatcgtgcta
    38161 tttgttagcg ttgggcttcg gtgatatagt ctgcgccacc tgatcgcagg tttttggctt
    38221 ttttcggtca ggttagccgt ggttttacac ggcttttttg tggatacaca aaatcattca
    38281 ggacgcatcg ggacggcagg cggatacgtt cccggcgtgc gcagacagcg cacgacaggg
    38341 gcgatgacgc gcagtcattc gcgaagcgaa ccgaagagaa tgtgtataaa ggcttcagta
    38401 ttcctgagta ccgctaaatc ctttcaggga caaaaaacgc gttatgttgt ctgcaactca
    38461 accagtaagc gaaaatttgc cagcacatgg ctgccgtcat gttgccataa ttatggatgg
    38521 caatggccgc tgggcgaaaa agcaagggaa gatccgggcc tttgggcata aagccggggc
    38581 gaagtccgtc cggcgagcgg tctcttttgc tgccaataac ggtattgatg cgttaacgct
    38641 gtatgccttt agtagtgaaa actggaaccg accagcgcag gaagtgagcg cgttaatgga
    38701 gctgtttgtg tgggcgctgg atagcgaagt caaaagcctg caccgccata acgttcgcct
    38761 gcgtattatc ggcgatatca gccgatttaa ctcacgttta caagaacgta ttcgcaaatc
    38821 agaagcgctt accgcccata atacggggct aacgttgaat atcgctgcga attacggcgg
    38881 acgttgggat attgtccagg gagtccgaca actggcggag ctggtgcagg ctggagtgct
    38941 gcgccccgat cagattgatg aagagagact aggccagcaa atctgtatgc atgagctggc
    39001 gcctgtggat ttagtaatta ggactggggg agagcatcgc attagtaact ttttgctttg
    39061 gcaaattgcc tatgccgaac tttactttac ggatgttctc tggcccgatt tcgatgaaca
    39121 agactttgaa ggtgcgctgc atgcctttgc taatcgagag cgtcgtttcg gcggtaccga
    39181 gcctggtgat gacaaagcct gatgggggtc gcttttgctg aagtatcgcc tgatttctgc
    39241 ttttgtgtta atacccgcgg tcatcgctgc gcttttttta ttgccgccgg tggggttcgc
    39301 cattattacg ctggttgtct gtatgctggc cgcgtgggaa tgggggcagt taagcggttt
    39361 cgccgcgcgt tcacagcggg tttggctggc ggtgctgtgt ggtctgttat tggcgctgat
    39421 gttatttttg ttgcctgagt atcatcacaa cattcgtcaa ccgctggttg agatgtcgct
    39481 ttgggcatcg ttaggatggt gggttgtcgc gctactgctg gtgctatttt atcccggttc
    39541 ggcggcaatc tggcgcaact caaaaacatt gcgtctcatt ttcggtttgt taactattgt
    39601 gccatttttc tggggcatgc tggcgctgcg cgcctggcac tatgacgaga atcattacag
    39661 tggcgcaata tggttactct atgtcatgat cctggtctgg ggagcggact ctggcgcgta
    39721 tatgtttggt aaattgtttg gcaaacataa gctggcgccg aaggtttccc cgggtaaaac
    39781 ctggcaaggg tttatcggcg ggcttgctac ggctgccgtg atctcatggg gttacggtat
    39841 gtgggcgaat ctgaatgttg cgcctgttat cttgctgatt tgctctgtgg tggcggctct
    39901 ggcttctgta ctgggcgacc tcaccgagag tatgtttaag cgcgaagcag gaattaagga
    39961 tagcggccac ttgatcccag gccatggcgg cattctggac cgaattgaca gtctgacggc
    40021 tgccgtaccg gtctttgctt gcctgttgtt actggtgttc aggacgctct aacggaaggt
    40081 tttatgctga gtattctctg gaatctggct gcattcatca tcgcactggg cgtgctgatc
    40141 actgtgcatg aatttggtca tttctgggtt gcccggcgct gcggtgtgcg agttgagcgc
    40201 ttttccatcg gttttggcaa agcgctctgg cgtcgtaccg atcggtacgg caccgagtat
    40261 gtcatcgccc tgatcccgct gggcggctac gtcaaaatgc tggatgagcg cgccgaaccg
    40321 gtagcgccgg aattgcgtcg tcacgccttc aataacaaaa cggtgggcca gcgcgccgca
    40381 attattgccg caggtccggt tgcgaacttc atttttgcta tctttgctta ctggctggtc
    40441 tttatcatcg gcgtccctgg cgttcgtccg gtcattggcg aaataacgcc caactcgatt
    40501 gctgcgcagg cgcaaattgc gcctggtacg gaacttaaag ccgttgatgg tatcgaaacc
    40561 cctgattggg atgccgtgcg tttacaactg gtgtccaaaa ttggcgatca gcagacgacg
    40621 gtgagcgtcg cgccgtttgg cagcgaccag cggcaggaca aaacgcttga tttacgtcac
    40681 tgggcatttg agcctgataa gcaagatcct gtatcttctt tagggattcg gccccgcggg
    40741 ccacagattg aaccggtact gtcagaagtg caggcgaatt ccgcagccag taaagcgggt
    40801 ttgcaagcag gcgacaggat cgttaaagtc gatggtcagc cgttaacgca gtggatgaaa
    40861 ttcgtgacgt ttgtacgtga taatcccggt aagccgttag cgttagagat tgaaaggcag
    40921 gggagcgcct tgtcgttgac gttaacgccg gatacgaaat cggttaacgg aaaggcggaa
    40981 gggtttgcag gcgtggtgcc taaaattatt cctctgccgg aagagtacaa gactatacgc
    41041 cagtatgggc cttttagcgc catcctcgaa gccacggata agacgtggca gttgatgaag
    41101 ctgacggtca atatgctggg taaattgata accggtgatg tgaaactgaa caacctcagt
    41161 gggccgattt ctatcgctca gggggctggg atgtcagcgg agttcggggt gatttattac
    41221 ctgatgttcc ttgcgctaat cagcgtgaac ttagggataa ttaacctgtt tccgctgccc
    41281 gttcttgacg ggggtcatct gctgttcctg gcgattgaaa agcttaaggg cgggccggta
    41341 tccgagcggg ttcaagactt tagttatcgc attggctcga ttttgctggt gttgttaatg
    41401 gggcttgcac ttttcaatga tttctctcgg ttgtaagaga gttagttagg aagaacgcat
    41461 aataacgatg gcgatgaaaa agttgctcat agcgtcgctg ctgttcagca gcgccaccgt
    41521 atacggtgct gaagggttcg tagtgaagga cattcatttc gaaggcctgc agcgagtcgc
    41581 cgttggtgcg gctctcctca gtatgccggt gcgcacaggc gacacggtta atgatgaaga
    41641 tatcagtaac accattcgcg ctctgttcgc caccggcaac tttgaggacg tccgcgtcct
    41701 gcgcgatggt aatacccttc tggttcaggt aaaagaacgt ccgaccattg ccagcatcac
    41761 tttctccggg aacaagtcgg tgaaagatga catgctcaag caaaacctcg aagcgtctgg
    41821 cgtacgtgtt ggcgagtctc tggatcgcac cacgctgtct gatatcgaaa aaggtctgga
    41881 agacttttac tatagcgtag gtaaatacag cgccagcgtt aaggcggtcg tcacgccgct
    41941 accgcgcaac cgtgttgatc ttaaactggt gttccaggag ggcgtatcgg cgaagatcca
    42001 acagatcaac atcgtcggta accatgcctt tagcaccgaa gaactcattt ctcatttcca
    42061 gttgcgtgac gaagtgccgt ggtggaacgt cgtcggcgat cgtaaatacc agaaacagaa
    42121 gctggcgggc gaccttgaaa ccttgcgcag ctactatctg gatcgcggct acgcgcgttt
    42181 caatattgac tccacgcaag tgagtctgac gccggataag aaagggatct acatcaccgt
    42241 caatatcacc gaaggcgatc agtacaagct ttccggggtt caggtgagcg gtaacctggc
    42301 cggacattcc gctgaaattg agaaactgac gaaaattgaa ccgggcgagc tctataacgg
    42361 caccaaagtg accaaaatgg aagatgacat caaaaagctt ctgggtcgct atggttacgc
    42421 ctatccgcgc gtgcagtcac agcctgaaat taacgatgct gacaaaaccg taaaactgcg
    42481 cgtgaacgtc gatgcgggca accgtttcta cgtgcgtaag atccgctttg aaggcaacga
    42541 tacctcaaaa gattccgttc tgcgccgtga aatgcgccag atggaagggg cgtggctggg
    42601 cagcgacctg gttgaccagg ggaaagagcg tctgaaccgt ctcggcttct ttgaaaccgt
    42661 cgacaccgac acgcagcgcg ttccggggag cccggatcag gttgatgtgg tgtacaaggt
    42721 gaaagagcgt aacaccggta gcttcaactt cggtatcggt tacggtacag aaagcggcgt
    42781 gagcttccag gccggcgttc agcaggacaa ctggttaggt accggttatt ccgtggggat
    42841 taacggtacc aaaaatgact accagaccta cagcgaactg tccgttacta acccatactt
    42901 taccgttgac ggcgtgagcc tcggtggtcg tatcttctat aacgactttg aagcggatga
    42961 tgccgacctg tccgactata ccaacaagag ttacggtacg gatgtgacgc ttggcttccc
    43021 catcaacgag tacaacacgt tgcgtgctgg tctgggctat gtccataaca aactgtccaa
    43081 catgcagccg cagatcgcga tggatcgtta tcttgaatcg atgggcgacc ctgatgccag
    43141 cgattttgcc gctgacgact tcacctttaa ctacggctgg acctataaca agcttgaccg
    43201 tggttatttc ccgacggacg gctcgcgagt caacctgacg ggtaaggtga cgattccagg
    43261 ttccgacaac gaatactaca aagtgtcgct ggataccgcg acctatgtgc ctattgataa
    43321 cgaccacaag tgggtggttc tggggcgtac tcgttggggt tacggcgatg gtttaggcgg
    43381 caaggaaatg ccgttctatg agaacttcta tgccggtggt tccagtaccg tgcgtggttt
    43441 ccagtcgaat actatcggcc cgaaagcggt ctataaaaat ggcgcccaca ctagttggga
    43501 cgatgatgat gattacgaag actgtactca ggaatcaggc tgtaaatcag atgatgcggt
    43561 aggtggtaat gccatggctg tcgccagcct ggaatttatt accccgacgc cgttcatcag
    43621 cgaaaagtat gccaactcgg ttcgtacctc cttcttctgg gatatgggta ccgtttggga
    43681 tacgaactgg gatccgtcat ctgcgccgtc agatgtaccg gattacagcg atccaggcaa
    43741 catccgtatg tccgcgggta tcgcattaca atggatgtcc ccattggggc cgttggtctt
    43801 ctcctacgcc cagccgttta aaaagtacga tggagacaaa gccgagcagt tccagtttaa
    43861 cattggtaaa acctggtaat tgttcactgc aaaggaatgc attggtagtg tagcgatgac
    43921 ttttggcgat gcccccaggg atcgccaggc cacgcaaaga gctgtacctt cgggtgcaaa
    43981 tgggatggta aggagtttat tgtgaaaaag tggttattag ctgcaggtct tggtttggcg
    44041 atggttacgt ccgcacaggc tgctgacaaa attgcaatcg tcaacatggg taatctgttc
    44101 caacaggttg cgcagaagac gggtgtatcc aatacactgg aaaacgaatt taaaggccgt
    44161 gcggctgaac tgcaaaaaat ggaaaccgat ctgcaatcta aaatgcagcg tctgcaatcc
    44221 atgaaagcag gtagcgatcg tactaagctg gaaaaagacg tgatgtctca gcgccagact
    44281 ttcgcacaaa aagcgcaggc ttttgagaaa gatcgcgctc gtcgttccaa cgaagaacgc
    44341 aacaaactgg tgactcgtat ccagactgcg gtgaaaaaag tggctaacga ccagagtatc
    44401 gatctggtgg tagacgcaaa caccgttgct tacaacagca gcgatgtgaa agacatcacc
    44461 gctgacgtac tgaaacaggt taaataagta atgccttcaa ttcgactggc tgacttagca
    44521 gaacagttgg atgcagaatt acacggtgat ggcgatatcg tcatcaccgg cgttgcgtcc
    44581 atgcaatctg caacaacagg ccacattacg tttatggtaa atcctaagta ccgtgaacac
    44641 ttaggtttat gccaggcttc tgcggttgtc atgacgcagg acgatcttcc ttttgccaag
    44701 agcgcggcgc tggtagttaa aaatccctac ctgacctacg cgcgcatggc gcaaatttta
    44761 gatactacgc cgcaacccgc gcagaatatc gcgccaagcg ccgtgattga tgcgacggca
    44821 acgctgggta gcaatgtttc agtcggcgcg aatgcggtga ttgaatctgg cgtacaactg
    44881 ggcgataacg tggttatcgg cgcaggctgt ttcgtcggaa aaaatagcaa aatcggggcg
    44941 ggttcacgct tgtgggcgaa cgtaacgatt taccacgaca ttcagatcgg tgagaattgc
    45001 ctgatccagt ccagtacggt gatcggcgcg gacggttttg gctacgctaa cgatcgtggc
    45061 aactgggtga agatcccaca actgggccgg gtcattattg gcgatcgtgt cgagatcggc
    45121 gcttgtacca ccattgaccg tggcgcgttg gatgatactg ttattggcaa tggcgtgatt
    45181 attgataatc agtgccagat tgcacataac gtcgtgattg gcgacaatac ggcagttgcc
    45241 ggtggcgtca ttatggcggg tagcctgaag attggccgtt actgcatgat tggcggcgcc
    45301 agcgtgatca atgggcatat ggaaatatgc gacaaagtca cggtaactgg catgggtatg
    45361 gtgatgcgtc ccatcacgga accgggcgtc tactcctcag gcattccgct gcaacccaac
    45421 aaagtatggc gtaaaactgc tgcactggtg atgaacattg atgatatgag caagcgtctc
    45481 aaagcgattg agcgcaaggt taatcaacaa gactaacgtt ccgccttgta gttgccattc
    45541 ttttccggcc tgtcacattc atacgattgc ggcaggccgt gttattattg cctttttgta
    45601 tatttggaca ggaagagtat tttgactact aacactcata ctctgcagat tgaagagatt
    45661 ttagagcttc tgccgcaccg ttttccgttt ttactggtcg atcgcgtgct ggactttgaa
    45721 gaaggtcgtt ttctgcgtgc ggtgaaaaat gtctccgtca acgagccgtt tttccagggg
    45781 catttcccgg gcaaaccgat tttgccaggc gtgctgattc tggaagcgat ggcgcaggca
    45841 accggtattc tggcgtttaa aagcgttggt aaactggaac ctggcgaact gtattatttc
    45901 gcgggtattg atgaagcgcg ctttaagcgt ccggtggtgc caggcgatca gatgatcatg
    45961 gaagtcactt tcgagaaaac gcgccgtggc ctgacccgct ttaaaggggt tgcgctggtc
    46021 gacggtaaag ttgtgtgcga agcaaccatg atgtgtgctc gtagccggga ggcctgattc
    46081 gtgattgata aatccgtctt tattcatcct accgccattg tggaagacgg cgctgtaatt
    46141 ggcgctaatg cccacattgg tcccttttgt attgttgggc cgcaggtcga aattggtgag
    46201 ggaaccgtac tgaagtctca tgtggtcgta aatggtcaaa ccaaaatcgg ccgcgacaac
    46261 gagatttatc agtttgcctc catcggtgaa gtgaaccagg atctgaaata tgcgggtgag
    46321 ccaacccgtg tggaaattgg cgatcgtaac cgcatccgcg aaagcgtcac cattcatcgt
    46381 ggtacagtgc agggcggtgg gttgacgaag gtgggtagcg ataacctgct gatgatcaat
    46441 gcgcatgtcg cacatgattg tacggtaggt aatcgctgta tcctcgccaa caacgccacg
    46501 ctggcggggc acgtatcagt cgatgatttt gcgatcatcg gcggtatgac ggcagttcat
    46561 caattctgca ttatcggtgc gcatgtgatg gtcggcggct gctccggcgt ggcgcaggat
    46621 gtccctccgt atgtgattgc gcagggtaac catgcgacgc cgttcggggt aaatatcgaa
    46681 gggctgaagc gtcgcggctt tagccgtgaa gggctggtgg cgattcgtaa tgcctacaaa
    46741 ctgttgtacc gcagtggtaa aacgctcgac gaagcgaagc tggaaatcgc tgaacttgct
    46801 gaaaagcatc cggaagtgaa ggcgtttacc gagttctttg agcgttcaac gcgcggtccg
    46861 attcgttaat ggcggcacag cgtcctttaa cgattgccct ggtcgccggt gaaacgtccg
    46921 gcgatattct tggcgcaggc ttaattcgtg cgctgaaagc gcgcgtaccc aacgcccgtt
    46981 ttgtgggcgt tgcggggccg cgtatgcagg ccgaagggtg tgaagcctgg tacgagatgg
    47041 aagagctggc ggtcatgggc attgttgaag tgctcggacg tttacgccgt ttgttgcata
    47101 tccgcgccga tctgacccgc cgttttaccg aactcaagcc cgatgtcttt gtcgggattg
    47161 atgcccctga tttcaatatt accctcgaag gtaatctgaa aaaacaaggg attaagacca
    47221 ttcattatgt cagcccgtcc gtttgggcct ggcgacagaa acgcgttttc aaaataggca
    47281 gatccaccca tatggtgttg gcttttctgc ctttcgaaaa agcgttttac gataaattta
    47341 acgtcccgtg ccgctttatc ggtcacacca tggcggatgc catgccgctg gacccggata
    47401 aaaatgcggc gcgcgacgtg ctgggtatcc cgcatgacgc ccattgtctg gcgctactgc
    47461 caggcagccg tggcgcggaa gtggaaatgc tcagcgccga cttcctgaaa accgcacaat
    47521 tgctgcgaca gcgctatccc gatctggaag tggtagtgcc gctggtgaac gcgaaacgcc
    47581 gcgagcagtt tgaaaaaatt aaagcggagg ttgcgccgga tctcgccgtt catttgctgg
    47641 acggcatggc gcgcgaggcg atgatcgcca gcgacgcggc gttgctggcc tcaggcacgg
    47701 cggcactgga gtgtatgctg gcaaaatgcc cgatggtagt ggggtatcgt atgaagccct
    47761 tcactttctg gctggcgaaa cgtctggtga aaacggagta tgtgtctttg cctaacctgc
    47821 tggcgggaag agaattagtc aaagagctgt tgcaggaaga gtgcgaaccg caaaaactcg
    47881 ccgaagcgct gttgccgcta ctggcgaacg gtaaaaccag ccatgcgatg cacgacacct
    47941 tccgtgaatt gcatcagcag atccgctgta atgccgatga gcaggcggca gatgccgtcc
    48001 tggagttagc acaatgatcg aatttgttta tccacacacc catttagtgg cgggtgtgga
    48061 tgaagtgggc cgtggcccgc tggtgggcgc cgtagtgacc gccgccgtga tcctcgatcc
    48121 ggcgcgtccg atcgtcggtc tgaatgattc caaaaaattg tctgaaaagc gtcgtctgtc
    48181 attgtatgac gagattaaag aaaaggcgtt aagctggagt ctgggacgcg cggaagcgca
    48241 tgaaattgat gagctgaata ttttgcacgc caccatgctc gccatgcagc gcgctgtcgc
    48301 tggtctgcat attgcgccag aatatgtgct gatcgacggc aatcgctgtc cggagctgcc
    48361 tgtgccgtca atggccgtgg tgaaaggcga cagccgcgtg gcggagatta gcgcggcgtc
    48421 tattctggcg aaagtcaccc gcgacgcaga aatggcggcg ctggatatcg tttttcctca
    48481 gtatggcttt gcgcagcaca aaggctatcc aaccgctttt catctggaaa agttggccca
    48541 gtatggcgcg acggcgcacc accgacgcag ttttgcgcct gttaaacgcg ctctgggact
    48601 tgtgtcctga ttcttgtatc gagaaatctg aagatgtctg aaccacgttt cgttcacctg
    48661 cgggtgcaca gcgactactc tatgatcgat gggctggcga agaccgggcc gctggtgaaa
    48721 aaggcggcct cattaggtat gcctgcgctg gcgatcaccg attttaccaa cctctgcggt
    48781 ctggtgaagt tctacggagc gggtcatggc gcgggcatta aacccatcgt cggggcggac
    48841 tttaacgttc acaacgaact gctgggagat gagctgactc atctgacggt actggcggcg
    48901 aataatacgg gataccagaa cctgacgttg ctgatctcga aagcgtatca gcgcggctac
    48961 ggcgcggcag gcccgattat cgagcgcgac tggctggtag agcttaaaga aggtttgatc
    49021 ctgctttccg gcgggcgcat gggcgacgta ggccgctgtc tgctacgcgg caaccaggcg
    49081 ctggtggagg agtgcgttgc tttctatgaa gcgcattttc ccgatcgcta cttcctggaa
    49141 ctgatccgta ccggcagaca ggatgaagag acctatctcc atgctgcggt tgagctggct
    49201 gaggcacgtg gtttgccggt tgtcgcgaca aacgatgtcc gtttccttga aagcgatgat
    49261 tttgacgccc atgagattcg tgtcgcgatt cacgacggtt tcacgctcga cgatcctaaa
    49321 cgtccacgca attattcacc gcagcagtat atgcgcagtg aagaagaaat gtgcgagctg
    49381 ttctccgata ttccggaggc gctggaaaat acggtggaga ttgccaaacg ctgcaacgta
    49441 acggtgcgtc tgggtgaata tttcctgccg cagttcccga ccggcgatat gaccaccgaa
    49501 gattatctgg tcaaaaaatc gaaagagggg ctggaagagc gtctggcttt cctgtttccg
    49561 gacgaagaag agcgcaaaaa gcgtcgcccg gaatatgacg agcgtctgga tattgaacta
    49621 caggttatca accagatggg gttccctggc tacttcctca tcgtgatgga gtttatccag
    49681 tggtcaaaag ataacggcgt gccggtaggg ccgggacgtg gttccggggc cggttcgctg
    49741 gtggcctacg cgctgaaaat taccgacctt gatccgctgg aatttgacct gctgttcgaa
    49801 cgtttcctga acccggaacg tgtctcgatg cctgacttcg acgttgactt ctgtatggag
    49861 aaacgcgacc aggtgattga gcacgtcgca gacatgtacg ggcgtgatgc ggtatcgcag
    49921 attatcacct tcggtacgat ggcggcgaaa gccgttatcc gcgatgtggg ccgcgtgctg
    49981 gggcatccgt acggttttgt cgatcgtatc tcgaagctgg tgccgcccga tccgggcatg
    50041 acgctggcaa aagcctttga agcggaaccg caactaccgg aaatttacga ggcggatgaa
    50101 gaggtcagag cgctgatcga tatggcgcgt aagctcgaag gcgtcacgcg taacgccggt
    50161 aagcacgctg gcggcgtggt catcgcgccg accaaaatta ccgactttgc gccgctgtac
    50221 tgcgatgaag agggcaagca tccggttacc cagtttgata aaagcgacgt ggaatatgcc
    50281 gggctggtga agttcgactt cctcggtttg cgtacgctga ctatcatcaa ctgggcgctg
    50341 gagatgatca acaagcggcg ggcgaagaat ggcgagccac cgctggatat cgccgccatt
    50401 ccgctggacg ataaaaaaag cttcgacatg ctgcaacgct cggaaaccac ggcggtcttc
    50461 cagcttgaat cgcgcggtat gaaagacctg atcaagcgtc tgcaacctga ctgctttgaa
    50521 gatatgatcg cgctggtggc cctgttccgt cccggcccgt tgcagtcagg gatggtagat
    50581 aactttatcg atcgtaagca cggtcgtgaa gaactctctt acccggacgt tcagtggcag
    50641 catgaaagcc tgaagccggt actggagccg acctacggca tcattctgta tcaggaacag
    50701 gtgatgcaga ttgcccaggt actttccggg tatactctcg gtggcgcgga tatgctgcgt
    50761 cgtgcgatgg gtaagaaaaa gccggaggag atggccaaac agcgttccgt ttttgaagag
    50821 ggcgcgaaaa agaacggtat cgacggcgaa ctggcgatga aaatctttga cctggtggag
    50881 aaattcgccg gttacgggtt taacaaatcg cactccgccg cttatgcgct ggtttcttat
    50941 cagacgctat ggctaaaggc gcactatccg gctgaattta tggcggcggt gatgactgcc
    51001 gatatggaca acaccgagaa ggtcgtcggc ctggtagacg agtgctggcg gatgggactg
    51061 aaaattctgc cgccggatat taactccgga ttgtaccatt tccacgttaa tgatgagggc
    51121 gagatcgtct acggcatcgg cgcgatcaaa ggcgtcggcg aagggccgat cgaagcgatc
    51181 atcgacgcgc gtaatcaggg cggctatttc cgcgaactgt ttgatctgtg cgcgcggacc
    51241 gacaccaaaa agctcaaccg ccgggtgctg gaaaagctga tcatgtccgg ggcgttcgac
    51301 cgcctggggc cgcaccgcgc cgcgctgatg aactcattgg gcgatgcgct gaaagccgcc
    51361 gaccagcacg ccaaagcgga agctatcggt caggcggata tgttcggcgt actggcggaa
    51421 gagccggagc aaatcgaaca atcctatgcc agctgccagc cgtggccgga gcaggtggtg
    51481 ttagatgggg aacgtgaaac gttggggctg tacctgacgg gccaccctat caatcagtat
    51541 ttaaaagaaa ttgagcgcta tgtcggcggg gtaaggctca aagacatgca tccgacagaa
    51601 cgtggtaaag tcaccacggc tgcggggctc gtgattgccg caagggttat ggtcaccaag
    51661 cgcggcaatc gtatcggcat ctgtacgctg gatgaccgtt ccgggcgtct ggaagtgatg
    51721 ttatttaccg acgcgctgga taaataccag cagttgctgg aaaaagaccg catacttatc
    51781 gtcagcggac aggtcagctt tgatgacttc agcggggggc ttaaaatgac cgcccgcgaa
    51841 gtgatggata ttgacgaagc tcgcgaaaaa tacgctcgcg ggcttgctat ctcgctgacg
    51901 gacaggcaaa ttgatgacca gcttttaaac cgactccgtc agtctctgga accccaccgc
    51961 tcggggacca ttccagtaca tctctactat cagagggcgg atgcgcgtgc gcggctgcgt
    52021 tttggcgcaa cgtggcgtgt ctctccgagc gatcgtttac ttaacgatct gcgtggcctc
    52081 attggttcgg agcaggtgga actggagttt gactaataca ggaatactat gagtctgaat
    52141 ttccttgatt ttgaacagcc gatagcagag ctggaagcga aaatcgattc tctgactgcg
    52201 gtaagccgcc aggatgagaa actggatatt aatatcgatg aagaagtcca tcgcctgcgc
    52261 gaaaaaagcg tagaactgac gcgcaaaatc ttcgccgatc tcggcgcatg gcaggtagcc
    52321 caactggcgc gccatccgca gcgtccgtac accttggatt atgtccgtct ggcgtttgat
    52381 gagtttgatg agctggcggg cgatcgcgcc tatgctgatg acaaagccat cgtcggcggt
    52441 atcgcgcgtc tggaagggcg accggtgatg atcattggtc atcagaaagg tcgtgaaacc
    52501 aaagaaaaaa ttcgtcgtaa ctttggcatg ccagcgccgg aaggctaccg caaagcgctg
    52561 cgcctgatgg aaatggctga acgcttcaac atgccgatta tcaccttcat cgacaccccg
    52621 ggcgcttacc ctggcgtggg cgcggaagag cgtggtcagt ctgaagctat cgcccgcaac
    52681 ctgcgtgaga tgtctcgtct gaacgtaccg gtcatctgca ccgtgattgg cgaaggcggc
    52741 tccggcggcg cattggcgat tggcgtgggt gataaagtga atatgctgca atacagcacc
    52801 tattccgtta tctccccgga aggttgcgcc tctattttgt ggaagagcgc cgacaaagcg
    52861 ccattggctg ctgaagcgat gggcatcatc gcgccgcgtc tgaaagagct gaagctaatc
    52921 gattccatca ttccggagcc gctgggcggc gcgcaccgta atccggaagc gatggcggcg
    52981 tcgctaaaag cgcagctgct ggaagattta gccgatctcg atgtgttaag caccgatgat
    53041 ttaaaaaacc gtcgttacca gcgtttgatg agctacggtt acgcctaatc atttacctca
    53101 tttctcccag gaggccggat aatccggcct cttttttgtc tatggaaa
//
LOCUS       DAJVBX010000007        52794 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.007, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000007 DAJVBX010000000
VERSION     DAJVBX010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 52794)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52794)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52794
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.007"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            92..1318
                     /locus_tag="OPV72_000351"
     CDS             92..1318
                     /locus_tag="OPV72_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3748 domain-containing protein"
                     /protein_id="HCR9912758.1"
                     /translation="MKQITFTPRHHQLTNTNTWTPDSQWLVFDVRPSGASFTGKTIER
                     VNVHTGDVEVIYRAVQGAHVGVVTVHPADNYYVFIHGPENPDETWHYDFHHRRGVIAT
                     PGGVTNLDAMDITAPYTPGALRGGSHVHVFSPNGELVSFTYNDHVLHECDPALDLRNV
                     GVAAPYGPVTVPVQHPREYSGSHWCVLVSRTTPAPRPGSDDINRAYEEGWVGNRQIAF
                     IGDTLSLTGQKVPELFIVDLPCHENGWKQAGDTPLTGTESTMPSPPLGVVQRRLTFTH
                     QRVYPGLTNEPRHWVRSNPQATAIAFLMRDDNGVAQLWLISPQGGEPRQLTHHATGVQ
                     SAFNWHPSGKWLGLVLENRIACCDAQSGKIDFLTARHDNPPSADAVVFSPDGRHVAWM
                     EEVKGFRQLWVTETGR"
     gene            complement(1320..1652)
                     /locus_tag="OPV72_000352"
     CDS             complement(1320..1652)
                     /locus_tag="OPV72_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001675643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceK/YidQ family lipoprotein"
                     /protein_id="HCR9912759.1"
                     /translation="MIKNVWLTLIIWNGMLLLGGCSSVMSHTGGKEGTYPGTRASATM
                     IGNDETNWGTKSLAILDMPFTAVMDTILLPWDIFRKDSSVRSRVEKSEEETKMTNAVI
                     PPAKMPPP"
     misc_feature    1895..1968
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01832"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ROSE (Repression Of Heat Shock gene Expression)
                     occurs in the 5'-region of heat shock genes and acts as an
                     RNA thermometer to modulate expression; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF01832"
     gene            1962..2375
                     /gene="ibpA"
                     /locus_tag="OPV72_000353"
     CDS             1962..2375
                     /gene="ibpA"
                     /locus_tag="OPV72_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006687722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock chaperone IbpA"
                     /protein_id="HCR9912760.1"
                     /translation="MRNFDLSPLYRSAIGFDRLFNLLENNQSQSNGGYPPYNVELVDE
                     NHYRIAIAVAGFAESELEITAQDNLLVVKGAHADEQKERTYLYQGIAERNFERKFQLA
                     ENIHVRGANLVNGLLYIELERVIPEANKPRRIEIN"
     gene            2485..2913
                     /gene="ibpB"
                     /locus_tag="OPV72_000354"
     CDS             2485..2913
                     /gene="ibpB"
                     /locus_tag="OPV72_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462708.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock chaperone IbpB"
                     /protein_id="HCR9912761.1"
                     /translation="MRNYDLSPLLRQWIGFDKLANALQNSGESQSFPPYNIEKSDDNH
                     YRITLALAGFRQEDLDIQLEGTRLTVKGTPEQPENEPKWLHQGLVMQPFSLSFTLAEN
                     MEVSGATFTNGLLYIDLTRNEPETIPPQRIAINERSALNS"
     gene            3107..4768
                     /locus_tag="OPV72_000355"
     CDS             3107..4768
                     /locus_tag="OPV72_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative transporter"
                     /protein_id="HCR9912762.1"
                     /translation="MSDIALTVSVLALVAVVGLWIGNIKVRGVGFGIGGVLFGGIIVG
                     HFVDQAGVTLSGDMLHFIQEFGLILFVYTIGIQVGPGFFASLRVSGLRLNLFAVLIVI
                     MGGLVTAILHKIFAIPLPVVLGIFSGAVTNTPALGAGQQILRDLGTPVDLVDQMGMSY
                     AMAYPFGICGILLTMWLMRLIFRVNVEAEAQKHESSLANGHSLIQTMNIRVENPNLNN
                     MAIQDVPILNSDKIICSRLKRDDTLMVPSPGTIIQAGDLLHLVGQPTDLHNAQLVIGK
                     EVDTSLSTRGTDLRVERVVITNEKVLGKRIRDLHFKERYDVVISRLNRAGVELVASSD
                     ASLQFGDILNLVGRPASIDAVANVVGNAQQKLQQVQMLPVFIGIGLGVLLGSIPLFVP
                     GFPVALKLGLAGGPLIMALILGRIGSIGKLYWFMPPSANLALRELGIVLFLAVVGLKS
                     GGDFVDTLTQGEGLSWIGYGIFITAIPLITVGLLARIFAKMNYLTLCGMLAGSMTDPP
                     ALAFANNLHATSGAAALSYATVYPLVMFLRIITPQLLAVIFWGMG"
     gene            5211..5558
                     /locus_tag="OPV72_000356"
                     /pseudo
     CDS             5211..5558
                     /locus_tag="OPV72_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462706.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YidH family protein"
     gene            5548..5910
                     /locus_tag="OPV72_000357"
     CDS             5548..5910
                     /locus_tag="OPV72_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF202 domain-containing protein"
                     /protein_id="HCR9912763.1"
                     /translation="MPDSRKARRQNDPGLQPERTSLAWFRTLLGYGALMALAVRHYWH
                     QAGFLFWVSISVLAIVAVILWRYTLSRNLMDVAHSDFSETHVMRDKFLISLAVLSLAI
                     LFAVTHIRQLIAFIGDFI"
     gene            5907..6437
                     /locus_tag="OPV72_000358"
     CDS             5907..6437
                     /locus_tag="OPV72_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HCR9912764.1"
                     /translation="MTGRQDIVVSNDQIQVVVNRQNSQRPQQLYRNLQRLGIRNVHFI
                     PLLEHDRNGMLTEDSLCSADWGRFLNSVFDIWVREDIQRISVRLFDETLQQWCGGRNG
                     AKTPDKAPLSAECQKCSLLRFCGGGCPEHRDSQGKNQLCEGYQTFFNYSSPHMRVMRD
                     LLKQHRSPEELMAMLR"
     gene            complement(6519..7841)
                     /gene="dsdA"
                     /locus_tag="OPV72_000359"
     CDS             complement(6519..7841)
                     /gene="dsdA"
                     /locus_tag="OPV72_000359"
                     /EC_number="4.3.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-serine ammonia-lyase"
                     /protein_id="HCR9912765.1"
                     /translation="MENILKLIARYPLVEDLVALKETTWFNPGATSLAQGLPYVGLTE
                     QDVNAAHDRLARFAPYLAKAFPQTAAAGGIIESDVVAIPAMQKRLEKEYGQTIDGEML
                     LKKDSHLAISGSIKARGGIYEVLTHAEKLALEAGLLTTDDDYSVLLSPEFKQFFSQYS
                     IAVGSTGNLGLSIGIMSACIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEDDYGVAV
                     EQGRKAAQSDPNCFFIDDENSRTLFLGYAVAGQRLKAQFAQQGRVVDASHPLFVYLPC
                     GVGGGPGGVAFGLKLAFGDNVHCFFAEPTHSPCMLLGVYTGLHDAISVQDIGIDNLTA
                     ADGLAVGRASGFVGRAMERLLDGLYTLDDQTMYDMLGWLAQEEGIRLEPSALAGMAGP
                     QRICASVAYQQRHGFSQTQLGNATHLIWATGGGMVPEDEMEQYLAKGR"
     gene            complement(7859..9196)
                     /gene="dsdX"
                     /locus_tag="OPV72_000360"
     CDS             complement(7859..9196)
                     /gene="dsdX"
                     /locus_tag="OPV72_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-serine transporter DsdX"
                     /protein_id="HCR9912766.1"
                     /translation="MHAQIWVVSTLLISIVLIVLTIVKFKFHPFLALLLASFFVGAMM
                     GIGPLEMVTAIENGIGGTLGFLAAVIGLGTILGKMMEVSGAAERIGLTLQRCRWLSAD
                     VIMVLVGLICGITLFVEVGVVLLIPLAFSIAKKTHTSLLKLAIPLCTALMAVHCVVPP
                     HPAALFVANKLGADIGSVIVYGLLVGLMASLVGGPLFLKFLGNRLPFKPVPTEFADLE
                     VRAENTLPSLGATLFTVLLPIGLMLVKTVAELNMAKDGTLYTLLEFIGNPITAMFIAV
                     FVAYYILGLRQHMGMSALLTHTENGFGAIANILLIIGAGGAFNAILKSSGLADTLAVI
                     LSNMHMHPILLAWLVALILHAAVGSATVAMMGATAIVAPMLPLYPDVSPEIIAIAIGS
                     GTIGCTIVTDSLFWLVKQYCGATLNETFKYYTTATFIASVVALAGTFLLSFII"
     gene            9422..10345
                     /gene="dsdC"
                     /locus_tag="OPV72_000361"
     CDS             9422..10345
                     /gene="dsdC"
                     /locus_tag="OPV72_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator DsdC"
                     /protein_id="HCR9912767.1"
                     /translation="MEPLRDTRNRLLNGWQLSKLYTFEVAARHQSFALAADELSLSPS
                     AVSHRINQLEAELGIQLFVRSHRKVELTHEGKRVFWALKSSLDTLNQEILDIKNQELS
                     GTLTVYSRPSIAQCWLVPALGDFTRRYPSISLTMLTGNDNVNLQRAGIDLAIYFDDAP
                     SAQLTHHFLMDEAILPVCSPDYARRFALQDNLNNLRHCTLLHDRQAWSNDSGTDEWHS
                     WAQHFAVNLPDSSGIGFDRSDLAVIAAMNHIGVAMGRKRLVQKRLDSSELIAPFGDMR
                     LKCHQHYYVTTLPGRQWPKIEAFIRWLQEQV"
     gene            10409..11494
                     /locus_tag="OPV72_000362"
     CDS             10409..11494
                     /locus_tag="OPV72_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulase family glycosylhydrolase"
                     /protein_id="HCR9912768.1"
                     /translation="MVKILGGVVFKPLIASLILTSAVVYAKPMPLTAARYAQQLGVGM
                     DVDWARTERGIREFDPLVVRDFKAKGLTHVRIRVAGAPTEARLIHLRKLVEACEYYGV
                     IPIIAYQADAYKTDPSASHEKELINWWSVVARYFGQTSPLLGFDLIYEPADKLNHNMA
                     SLNRVYDKTIRLIHAIDPQRMIFVAPRMRAAPEDLSALKLPAQSQNYVLAEWHIFPWG
                     PLKSGGKYPWTSGTTAEKAAIRARINAAVRWQHKTGHASWVGGWAPGESIKMTPIASQ
                     FAFARFMACELKKAHIPYAINADTQFYDGEEGAWRPAQEPLLNAMIAPECETPGKKPG
                     EGNVKPSVPDAISVTPAAASTPRSAIP"
     gene            complement(11421..12605)
                     /gene="emrD"
                     /locus_tag="OPV72_000363"
     CDS             complement(11421..12605)
                     /gene="emrD"
                     /locus_tag="OPV72_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EmrD"
                     /protein_id="HCR9912769.1"
                     /translation="MKRQRNVNLLLMLVLLVAVGQMAQTIYIPAIADMAQALNVREGA
                     VQSVMAAYLLTYGVSQLFYGPLSDRVGRRPVILVGMSIFMVATLIAMTTHSLTVLIAA
                     SAMQGMGTGVGGVMARTLPRDLYEGTQLRHANSLLNMGILVSPLLAPLIGGLLDTLWN
                     WRACYAFLLVLCAGVTFSMARWMPETRPAGAPRTRLIASYKTLFGNGAFNCYLLMLIG
                     GLAGIAVFEACSGVLMGAVLGLSSMVVSILFILPIPAAFFGAWFAGRPNKRFSALMWQ
                     SVICCLLAGLMMWIPGWFGVMNVWTLLIPAALFFFGAGMLFPLATSGAMEPFPFLAGT
                     AGALVGGLQNIGSGVLAWLSAMLPQTGQGSLGLLMTLMGLLILACWLPLASRISHQGQ
                     TV"
     gene            complement(12808..13668)
                     /locus_tag="OPV72_000364"
                     /pseudo
     CDS             complement(12808..13668)
                     /locus_tag="OPV72_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462698.3"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
     gene            complement(13761..13850)
                     /gene="tisB"
                     /locus_tag="OPV72_000365"
     CDS             complement(13761..13850)
                     /gene="tisB"
                     /locus_tag="OPV72_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_453107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin TisB"
                     /protein_id="HCR9912770.1"
                     /translation="MSVVDITILILKLIVAALQLLDAVLKYLK"
     gene            complement(13847..13961)
                     /locus_tag="OPV72_000366"
                     /pseudo
     CDS             complement(13847..13961)
                     /locus_tag="OPV72_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009325922.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            14484..14582
                     /gene="ivbL"
                     /locus_tag="OPV72_000367"
     CDS             14484..14582
                     /gene="ivbL"
                     /locus_tag="OPV72_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ilvB operon leader peptide IvbL"
                     /protein_id="HCR9912771.1"
                     /translation="MNPSMLNATLLTTAPSRAVVVVRVVVVVGNAP"
     gene            14689..16377
                     /gene="ilvB"
                     /locus_tag="OPV72_000368"
     CDS             14689..16377
                     /gene="ilvB"
                     /locus_tag="OPV72_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HCR9912772.1"
                     /translation="MASSGTTSTPQRFTGAEFIVHFLERQGIRIVTGIPGGSILPVYD
                     ALSQSTQIRHILARHEQGAGFIAQGMARTESKPAVCMACSGPGATNLVTAIADARLDS
                     IPLICITGQVPASMIGTDAFQEVDTYGISIPITKHNYLVRNINELPQVMSDAFRLAQS
                     GRPGPVWIDVPKDVQTATIELDALPSPAEKSPPPEFSAESIREAAAMINAAKRPVLYL
                     GGGVINAPTRVRELAEKAQLPTTMTLMALGMLPKAHPLSLGMLGMHGARSTNFILQEA
                     DLLIVLGARFDDRAIGKTEQFCPNAKIIHVDIDRAELGKIKQPHVAIQADVDDVLAQL
                     IPHIEAQPREAWHQLVADLQQEFPCGIPQENNPLSHYGLINAVAACVDDNAIITTDVG
                     QHQMWTAQAYPLNRPRQWLTSGGLGTMGFGLPAAIGAALANPGNKVLCFSGDGSLMMN
                     IQEMATASENQLDVKIILMNNDALGLVHQQQSLFYKQGVFAATYPGSINFMQIAAGFG
                     LDTCDLNNEADPQAALQAIIRRPGPALIHVRIDAEEKVYPMVPPGAANTEMVGE"
     gene            16381..16671
                     /gene="ilvN"
                     /locus_tag="OPV72_000369"
     CDS             16381..16671
                     /gene="ilvN"
                     /locus_tag="OPV72_000369"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HCR9912773.1"
                     /translation="MQKQSHDNVILELTVRNHPGVMTHVCGLFARRAFNVEGILCLPI
                     QGSDQSRIWLLVNDDQRLEQMISQIDKLEDVAKVVRNQSDPTMFNKIAVFFE"
     gene            complement(16673..17458)
                     /locus_tag="OPV72_000370"
     CDS             complement(16673..17458)
                     /locus_tag="OPV72_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HCR9912774.1"
                     /translation="METKQKERIRRLMELLKKTDRIHLKDAARMLEVSVMTIRRDLSQ
                     DDDPLPLTLLGGYIVMVNKPASSTNMPLPAKKTHHRDDLPVAILAAGLVRENDLVFFD
                     NGPEMPLVISMIPDDITFTGICYSHRVFIALNEKPNATAILCGGTYRAKSDAFYDANN
                     PSALDSLNPRKVFISASGVHEHFGVSWFNPDDLAAKRKAMERGLRKILLARHALFDEV
                     APASIGPLSAFDVLISDRPLPTDYAVHCRNGSVKVITPDSESE"
     gene            17772..18692
                     /gene="rbsK"
                     /locus_tag="OPV72_000371"
     CDS             17772..18692
                     /gene="rbsK"
                     /locus_tag="OPV72_000371"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HCR9912775.1"
                     /translation="MDIAVIGSNMVDLITYTNQMPKEGETLEAPAFKIGCGGKGANQA
                     VAAAKLNSKVLMLTKVGDDIFADNTIRNLESWGINTTYVEKVPCTSSGVAPIFVNANS
                     SNSILIIKGANKFLSPEDIDRAAEDLKKCQLIVLQLEVQLETVYHAIEFGKKHGIEVL
                     LNPAPALRELDMSYACKCDFFVPNETELEILTGMPVDTYDHIRAAARSLVDKGLNNII
                     VTMGEKGALWMTRDQEVHVPAFRVNAVDTSGAGDAFIGCFAHYYVQSGDVEAAMKKAV
                     LFAAFSVTGKGTQSSYPSIEQFNEYLSLNE"
     gene            18723..20039
                     /gene="fucP"
                     /locus_tag="OPV72_000372"
     CDS             18723..20039
                     /gene="fucP"
                     /locus_tag="OPV72_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose:H+ symporter permease"
                     /protein_id="HCR9912776.1"
                     /translation="MNDKNIVQMPDGYLNKTPLFQFILLSCLFPLWGCAAALNDILIT
                     QFKSVFSLSNFASALVQSAFYGGYFLIAIPASLVIKKTSYKVAILIGLTLYIVGCTLF
                     FPASHMATYTMFLAAIFAIAIGLSFLETAANTYSSMIGPKAYATLRLNISQTFYPIGA
                     AAGILLGKYLVFSEGESLEKQMAGMNAEQVHNFKVLMLENTLEPYKYMIMVLVVVMVL
                     FLLTRFPTCKVAQTASHKRPSALDTLRYLASNARFRRGIVAQFLYVGMQVAVWSFTIR
                     LALELGDINERDASTFMVYSFACFFIGKFIANILMTRFNPEKVLILYSVIGALFLAYV
                     ALAPSFSAVYVAVLVSVLFGPCWATIYAGTLDTVDNEHTEMAGAVIVMAIVGAAVVPA
                     IQGYVADMFHSLQLSFLVSMLCFVYVGVYFWRESKVRGNLAEVAAS"
     gene            20051..21064
                     /locus_tag="OPV72_000373"
     CDS             20051..21064
                     /locus_tag="OPV72_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HCR9912777.1"
                     /translation="MTTRITLWRELFSEQPRILLENDDFTVTAFRYASGVEGLKIQNS
                     RGHLVILPWMGQMIWDVQFDGHDLTMRNMFRQPKPAAEVVATYGCFAFHSGLLANGCP
                     SPEDTHPLHGEMPCAAMDDAWLELEGDSLRVTGRYEYVMGFGHHYQAQPAVVMRKSSA
                     LFDIQMTVTNLASVAMPLQYMCHMNYAYVPNATFRQNIPDTALKLRESVPAHVKPTAQ
                     WLAFNQRLLQGEASLATLNEPGFYDPEIVFFADELDKYTDTPEFSMIAPDGTTFVTRF
                     ASAELNYVTRWILYNGDQQVAAFALPATCRPEGFLAAQRNGTLLQLEPQQTRTFTVTT
                     GIV"
     gene            21218..21808
                     /gene="uhpA"
                     /locus_tag="OPV72_000374"
     CDS             21218..21808
                     /gene="uhpA"
                     /locus_tag="OPV72_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator UhpA"
                     /protein_id="HCR9912778.1"
                     /translation="MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLP
                     GRGVQVCICDISMPDISGLELLSQLPKGMATIMLSVHDSPALVEQALNAGARGFLSKR
                     CSPDELIAAVHTVATGGCYLTPDIAVKLAAGRQDPLTKRERQVEEKLAQGMAVKEIAA
                     ELGLSPKMVHVHRANLLEKLGVSNDVELAHRMFDGW"
     gene            21808..23310
                     /gene="uhpB"
                     /locus_tag="OPV72_000375"
     CDS             21808..23310
                     /gene="uhpB"
                     /locus_tag="OPV72_000375"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal transduction histidine-protein
                     kinase/phosphatase UhpB"
                     /protein_id="HCR9912779.1"
                     /translation="MNTFFSRLITVVACFFIFSAAWFCLWSISLHLVERPELAALLFP
                     FGLRLGLMLQCPRGYWPVLLGAEWLLVYWLAQEVALAHLPLLMIGGVLTLLPVALTSR
                     YRHQRDWRTLLLQGAALTAAALLQSLPWLGQGEAAWNALLLTLTGGLTLAPICLVFWH
                     YLTSTTWLPLGPSLVSQPVNWRGRHLIWYLLLFIVSLWLQLGLPAELSRFTPFCLALP
                     IIALAWHYGWQGALIATLMNAIALIASQTWHDHPVDLLLSLLAQSLTGLLLGAGIQRL
                     RELNQSLQKELARNHRLAERLLETEESVRRDVARELHDDIGQTITAIRTLAGIVQRLA
                     ADNGGVKQSGQLIEQLSLGVYDAVRRLLGRLRPRQLDDLTLAQAIRSLLREMELESRG
                     IVSHLDWRIDETALSESQRVTLFRVCQEGLNNIVKHANASAVTLQGWQQDERLMLVIE
                     DDGSGLPPGSHQQGFGLTGMRERVSALGGTLTISCTHGTRVSVSLPQRYV"
     gene            23320..24648
                     /locus_tag="OPV72_000376"
     CDS             23320..24648
                     /locus_tag="OPV72_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR9912780.1"
                     /translation="MLSFLKAPANAPLITDKHEVDARYRYWRRYILITIWLGYALFYF
                     TRKSFNAAAPEILASGILTRSDIGLLATLFYITYGVSKFVSGIVSDRSNARYFMGIGL
                     IATGVVNILFGFSTSLWAFALLWALNAFFQGFGSPVCARLLTAWYSRTERGGWWALWN
                     TAHNVGGALIPLVMAAVALHYGWRVGMMVAGLLAIGVGMVLCWRLRDRPQAIGLPPVG
                     DWRHDALEVAQQQEGAGLSRKEILAKYVLSNPYIWLLSLCYVLVYVVRAAINDWGNLY
                     MSETLGVDLVTANTAVSMFELGGFIGALVAGWGSDKLFNGNRGPMNLIFAAGILLSVG
                     SLWLMPFASYVMQAACFFTTGFFVFGPQMLIGMAAAECSHKEAAGAATGFVGLFAYLG
                     ASLSGWPLAKVLEIWHWTGFFAVIAIAAGISALLLLPFLNAQAPRETHEA"
     gene            24791..26182
                     /gene="uhpT"
                     /locus_tag="OPV72_000377"
     CDS             24791..26182
                     /gene="uhpT"
                     /locus_tag="OPV72_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexose-6-phosphate:phosphate antiporter"
                     /protein_id="HCR9912781.1"
                     /translation="MLAFLNQVRKPTLDLPLNVRRKMWFKSFMQSYLVVFIGYLTMYL
                     IRKNFNIAQNDMISTYRLSMTELGMIGLGFSITYGVGKTLVSYYADGKNTKQFLPFML
                     ILSAICMLGFSASMGAGSTSLFLMIAFYALSGFFQSTGGSCSYSTITKWTPRRKRGTF
                     LGFWNISHNLGGAGAAGVALFGANYLFDGHVIGMFIFPSIIALIVGFIGLRFGSDSPE
                     SYGLGKAEELFGEEISEEDKETEENEMTKWQIFVEYVLKNKVIWLLCFSNIFLYVVRI
                     GIDQWSTVYAFQELKLSKEVAIQGFTLFEVGALVGTLLWGWLSDLANGRRALVACVAL
                     ALIIATLGVYQHASNQYVYLASLFALGFLVFGPQLLIGVAAVGFVPKKAIGAADGIKG
                     TFDYLIGDSFAKLGLGMIADGTPVFGLTGWAGTFAALDAAAIGCICLMAMVAVMEERK
                     IRREKKIQQVNIA"
     gene            26375..26827
                     /locus_tag="OPV72_000378"
     CDS             26375..26827
                     /locus_tag="OPV72_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1198 domain-containing protein"
                     /protein_id="HCR9912782.1"
                     /translation="MIWLILATFVVVFIVGFRVLTSDTRRAIRRLSERLNIDVVPIES
                     MIDQMGKTAGGEFLQYLHRPDESHLQNAAQVLLIWQMVIVDGGDQNLQRWHRLLQKAR
                     LAAPITDTQVRLALGFLREMEPDMQEINAFQLRYNAFFQPEEGVHWLH"
     gene            27180..27923
                     /locus_tag="OPV72_000379"
     CDS             27180..27923
                     /locus_tag="OPV72_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCR9912783.1"
                     /translation="MKTLSKSSHIPLYQQVVEWIRESIYSGELVEDDRIPSEFQIMDM
                     LEVSRGTVKKAVDQLVREGVLVQVQGKGTFVKKENVAYPLGEGLLSFAEALASQKINF
                     TTSVITSRLEPANRFVAEKLSIKPGQDVLFLKRLRCIGDEKVMLIENRINIDLCPGII
                     DVDFTRENLFSAIERLSDKKISFSESRYAAKLIGNERGHYLDIGEDAPVLHLEQLVFF
                     SRGLAIDFGNVWLKGNKYYLGTILQRLDA"
     gene            27941..28414
                     /locus_tag="OPV72_000380"
                     /pseudo
     CDS             27941..28414
                     /locus_tag="OPV72_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462683.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
     gene            28411..28698
                     /locus_tag="OPV72_000381"
     CDS             28411..28698
                     /locus_tag="OPV72_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCR9912784.1"
                     /translation="MSKMILFVCATGVATSTAVAEKVMEYCKDNGLDVNYSQTNVASL
                     PNNTDGAALVVSTTKVPYELDIPVVSGLPIITGVGEDKVLEKIVSILKGQA"
     gene            28774..30132
                     /locus_tag="OPV72_000382"
     CDS             28774..30132
                     /locus_tag="OPV72_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HCR9912785.1"
                     /translation="MNDIAHTLYTVVQYVLGFGPTVLLPLVLFFLALFFKVKPAKALR
                     SSLIVGIGFVGIYAIFDILTSNVGPAAQAMVERTGISLPVVDLGWPPLAAITWGSPIA
                     PFVIPLTMLINVAMLALNKTRTVDVDMWNYWHFALAGTLVYYSTGSFVLGLSAAAIAA
                     IVVLKLADWSAPLVAKYFGLEGISLPTLSSVVFFPIGLLFDKIIDKIPGVNRIHIDPE
                     NVQKKMGIFGEPMMVGTILGVLLGIIAGYDFKHILLLGISIGGVMFILPRMVRILMEG
                     LLPLSEAIKKYLNAKYPGRDDLFIGLDIAVAVGNPAIISTALILTPISVFIAFLLPGN
                     KVLPLGDLANLAVMASMIVLACRGNIFRAVITAIPVIIADLWIATKIAPFITGMAKDV
                     NFKMAEGSSGQVSSFLDGGNPFRFWLLEIFNGNIIAIGLIPVLALVIYGVFRLTKGTV
                     YA"
     gene            30125..31609
                     /locus_tag="OPV72_000383"
     CDS             30125..31609
                     /locus_tag="OPV72_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase"
                     /protein_id="HCR9912786.1"
                     /translation="MPDYHAALVIDIGTTNCKVSCYSCHDVSVLEVRKFPTPTISSDK
                     GEVDLDIEALWQALRLVMAELVASVPFPVKNISIASFGESGVFVDKEGVILTPMLAWY
                     DRRGESYLSSLSKAEAEELYSITGLPPHSNYSAFKMRWLLDNYSLHERKDICWLHAPE
                     VLLWRMTGAKKTEISLASRTLCLDIARRTWSRNAAGILGIPFGVLAPLIKPGEVAGWV
                     TATLRQELGLPHEVKVTLAGHDHMVGARALQMQPGDVLNSTGTTEGILLLNTQPTLDV
                     QARRDKLANGCYSDGEFFTLFASLPVGGYALEWVKKTFRLTDKEISTGLEKVMEQYLK
                     PSWSVEHVPVFIPHLRGSGSPHKNQHTRGLLFGLTDSLPPESLLESVFIGLAMEFAHC
                     HGCFNIPAGRTVKVIGPAVKNPYWLQLKADILQCPIEAIAFDETVSLGALLIACPNVV
                     PPTVPVAERYFPDAVRSAKLKIYQQQWLSFYQFKLRQEGAFIGE"
     gene            31672..32532
                     /locus_tag="OPV72_000384"
                     /pseudo
     CDS             31672..32532
                     /locus_tag="OPV72_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462679.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase"
     gene            32542..32811
                     /locus_tag="OPV72_000385"
     CDS             32542..32811
                     /locus_tag="OPV72_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HCR9912787.1"
                     /translation="MIRQKVRVMNSTGLHARPAATLAKIVKKYQSSLTLVNNDKEIPI
                     KGMMSILGAGVKGNTMIDLICDGQDELAFMDELKSAFADGFGESV"
     gene            complement(32902..33225)
                     /locus_tag="OPV72_000386"
     CDS             complement(32902..33225)
                     /locus_tag="OPV72_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator"
                     /protein_id="HCR9912788.1"
                     /translation="MSAKTKFKSPAFEAIHSAASGLFSVDAIPQETMRSFDTACLSSI
                     KDLQPLEIKALREELNVSQSVFARYLNTSVSTVQKWESGAKRPSGMSLKLLNVVQKHG
                     LKVLV"
     gene            complement(33209..33567)
                     /locus_tag="OPV72_000387"
                     /pseudo
     CDS             complement(33209..33567)
                     /locus_tag="OPV72_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462676.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            33783..34976
                     /gene="nepI"
                     /locus_tag="OPV72_000388"
     CDS             33783..34976
                     /gene="nepI"
                     /locus_tag="OPV72_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine ribonucleoside efflux pump NepI"
                     /protein_id="HCR9912789.1"
                     /translation="MNENIAEKFRADGVARPNWSAVFAVAFCVACLITVEFLPVSLLT
                     PMAQDLGISEGVAGQSVTVTAFVAMFSSLFITQIIQATDRRYIVILFAVLLTASCLMV
                     SFANSFTLLLLGRACLGLALGGFWAMSASLTMRLVPARTVPKALSVIFGAVSIALVIA
                     APLGSFLGGIIGWRNVFNAAAVMGVLCVIWVVKSLPSLPGEPSHQKQNMFSLLQRPGV
                     MAGMIAIFMSFAGQFAFFTYIRPVYMNLAGFDVDGLTLVLLSFGIASFVGTSFSSYVL
                     KRSVKLALAGAPLLLALSALTLIVWGSDKTVAAAIAIIWGLAFALVPVGWSTWITRSL
                     ADQAEKAGSIQVAVIQLANTCGAAVGGYALDNFGLLSPLALSGGLMLLTALVVAAKVR
                     ITPMS"
     gene            complement(35036..36418)
                     /locus_tag="OPV72_000389"
     CDS             complement(35036..36418)
                     /locus_tag="OPV72_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCR9912790.1"
                     /translation="MRYRFPDNFWWGSACSALQTEGDSLNGGKSQTTWDVWFERQPDR
                     FHQGIGPAETSTFYRHWKQDIALLKQLKHNSFRTSLSWARLIPDGVGEVNPQAVSFYN
                     HVIDELLAQGITPFITLFHFDMPMVMQEKGGWENRDVVEAFGRYAQTCFTLFGDRVKH
                     WFTFNEPIVPVEGGYLYDFHYPNVVDFKRAATVAYHTVLAHSTAVRAWRAGRYDGEIG
                     VVLNLTPSYPRSQHPADVQAAHHADLLFNRSFLDPVLKGEYPAELVALLKTYDQLPAC
                     QPGDRQLIADGKIDLLGINYYQPRRVKCRDTAVNPQAPFMPEWLFDYYDMPGRKMNPY
                     RGWEIYAPGIYDIITNLRDNYGNPRCFISENGMGVENEQRFVQAGQIHDDYRIDFISE
                     HLKWLHKGISEGCHCLGYHMWTFIDNWSWLNGYKNRYGFVQLDLATQTRTVKKSGEWF
                     AATAEHNGFD"
     gene            complement(36524..36817)
                     /locus_tag="OPV72_000390"
     CDS             complement(36524..36817)
                     /locus_tag="OPV72_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9912791.1"
                     /translation="MKRKTLLLIATLVALPGVTYADSPFSSLQSAHEKNTILKDLRKM
                     CTPKGALTDEAWEKKIMASEGNQQHIREAMIAIERNNQHNYWQALGKVECPEM"
     gene            37014..37271
                     /locus_tag="OPV72_000391"
     CDS             37014..37271
                     /locus_tag="OPV72_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014341509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCR9912792.1"
                     /translation="MRRIEIVLGELERLTRGLCLADLAQETAFTAEAIGFNLGLARNS
                     VSKDLNQLWNDGLAIKSRGRPVYFLASPGAGNVAGTSAGRV"
     gene            37243..39813
                     /gene="dagR"
                     /locus_tag="OPV72_000392"
     CDS             37243..39813
                     /gene="dagR"
                     /locus_tag="OPV72_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014341510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator DagR"
                     /protein_id="HCR9912793.1"
                     /translation="MLGRQLEESEREVRSVADVLPHEEHYAPDDPFTSLIGYDRSLRD
                     AVEKGRAAVLYPHGLHVLLTGPSGVGKTFFAELMHRFACEQASGAIPPLVYFNCAEYA
                     HNPELLSSHLFGHRQGAFTGANEHKTGLVEQADGGYLLLDEVHRLSYEGQEKLFSILD
                     KGEYRPLGVSSQPRSISVRLICATTEPVGSALLRTFQRRIQVCIDLPGIRQRSVEEQI
                     ELIVGFLQRESRKIERTVSIDKPLLLWLLNKPLEGNIGQLKSDIQFLCAQAWASGMTE
                     HNDTLQLDKRLAEMSVNPTPEQRLLVDTLFDGKARLNIDARTLPALKTSLATGAEIEE
                     SDLFYSFLTREYVNLRNSNVPPAETLAILKNKLSSIFEYGLYSRDSVAHPPRYGDQIE
                     ERVTLLIGCVEQVLGFSLPENLVNPLRKHFLALIGYVQRGLIPQLYSSSLILDRCKDE
                     YDNATLLCRKINELLHIQCPATEVVWLCLFLKECRHYRQRIDASPDCGVILIAHGATT
                     ATSQAQYVNRVLERELFSAIDMPFEQSVHDTLETLTQMIQTRQYRRLILLVGIGSLIH
                     FGSTISKLFQIDVLLMPNITLTSLLEVGLDLSYETSDLPQLTALLQSKNIPCQLCTPQ
                     QENGGKVLVISCITGMGTAEKIKKVLEESFGELMSQDTRMVILDYNEVRSLERVQQAL
                     NASERLAGIVGTFQPGLPDIPFISLEELFSEQGPELVLSLLTPDLSNAERRLEMERSA
                     MRFISALTMESIINHISVLNPQRILKEMEGVFNHLTSSLSLKPSRQVTLRFLIHCCCM
                     VERIVINRKPLQMALERQPNLDARAFSVIKSAFLPIEDAYAIRLSDAEYFYIYELLYS
                     "
     gene            40035..40460
                     /locus_tag="OPV72_000393"
     CDS             40035..40460
                     /locus_tag="OPV72_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCR9912794.1"
                     /translation="MTTTQPLPHILLLTHGGWGQPLCNSLRMVTGEIKGVTEIALMPV
                     DTLGEFYQRVEAVVKTLPEGSLILTDFVGGTTSNVAARLSADYPVAVIAGLNASLLLE
                     ALDRREQGMLTACVDELVEAGRSSCLDVVAHVRQLQQSL"
     gene            40471..40956
                     /locus_tag="OPV72_000394"
     CDS             40471..40956
                     /locus_tag="OPV72_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HCR9912795.1"
                     /translation="MANIVLCRIDSRLIHGQVVTKWVGQSQANRIAVVSDELDADPFM
                     KNIYLMAAPPNIKVDCFGNQSFAAAWKENQLGDGNVLVLFPSLAAVQDAIQLGFDVTR
                     IQVGGLGGGPNRKAVFQNITLDEKDVGILNDLKNRGVQVFFQTIPEDKPQPLDDILKK
                     F"
     gene            41102..41851
                     /locus_tag="OPV72_000395"
     CDS             41102..41851
                     /locus_tag="OPV72_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCR9912796.1"
                     /translation="MDTLLFASLMGLYYWFARLRLGYTFSAMLLQPVVIAVFVGLLLG
                     NMQTAMIIGAGMQLVYLGVTSTPGGNVPSDPALAACISIPIAVKAGMDPNLAIALAIP
                     FGVIGVFLDQLRRTLNAAWVHMADKHAETANMAGIMRCAFLYPALLGLVLRFPVVFAA
                     NYFGQDVVESFLKLMPHWLTHSFEIMGGILPALGFAITIMVIGKKSLLPWFIGGFFAV
                     LYLKVDIMAMAIFGTCVAFLIKGLAKNEGAA"
     gene            41848..42708
                     /locus_tag="OPV72_000396"
     CDS             41848..42708
                     /locus_tag="OPV72_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462668.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCR9912797.1"
                     /translation="MMSSDVMQHELVERARESGALTKADITKAWFIYWLGAEVSSSYE
                     RLQSLIFCASMTPIIKKLYPQKEEQVEALKRHLNFFNSEQTFGAVIQGISIAMEEQKT
                     RGEPINDSSITGIKTGLMGPLAGMGDSIIWAAVMPLLIAIFIPFAANGSAMGGIIPLI
                     LYPAITLAISYGMVHKGYTLGRDSIIGLLQGGRIKELIYGANVLGLIMMGALSASYVK
                     ITTPLKISALKGSEVVVQQILDSIAPGLLPLAAVFAIYFYLVKKGPRYTTILLSIVAL
                     SIVCSLLGVL"
     gene            42712..43821
                     /gene="dgaE"
                     /locus_tag="OPV72_000397"
     CDS             42712..43821
                     /gene="dgaE"
                     /locus_tag="OPV72_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-glucosaminate-6-phosphate ammonia lyase"
                     /protein_id="HCR9912798.1"
                     /translation="MTPNIYQQLGLKKVINACGKMTILGVSSVAPEVMQATARAASAF
                     VEIDALVEKTGELVSRYTGAEDSYITSCASAGIAIAVAAAITHGDRARVALMPDSTGM
                     ANEVVMLRGHNVDYGAPVTSAIRLGGGRIVEVGSSNLAARWQLESAINEKTAALLYVK
                     SHHCVQKGMLSIDDFVQVAQANHLPLIVDAAAEEDLRGWVVSGADMVIYSGAKAFNAP
                     TSGFITGKKTWIAACKAQHQGIARAMKIGKENMVGLVYALENYHQGQTTVTAAQLQPV
                     AEAISAIHGLYADIEQDEAGRAIWRIRVRVNASELGLNAQDVEAQLRGGEIAIYARKY
                     QLHQGVFSLDPRTVAEGEMALIVARLREIAEHAAD"
     gene            43808..44551
                     /locus_tag="OPV72_000398"
     CDS             43808..44551
                     /locus_tag="OPV72_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HCR9912799.1"
                     /translation="MQQINFYRQRVAINVLAKDIANAKAIYEAAEGHAVIGVLSAQFA
                     TVEEGVPEVKRWMAEVPSISVGLGAGDPAQYYKAAMIAAHTHPAHVNQTFTGSGFAAG
                     ALAATGGEQTHINALVSPTGTPGEVVISTGVSSSQGMPARVSCEAAVRMMQDMGAHAA
                     KFFPMGGEKSLPELYALATTAARHGMTLIEPTGGISLDNFGIILQTCLEAGVPRVMPH
                     VYSSIIDPQTGNTRPEDIIQLMEIVKALV"
     gene            44787..45728
                     /locus_tag="OPV72_000399"
     CDS             44787..45728
                     /locus_tag="OPV72_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HCR9912800.1"
                     /translation="MKKSPTSTPHDAVFKTFLRHPDTARDFLNIHLPHLLRIRCDLTT
                     LKLAPDSFIEKNLRAFYSDVLWSLKTCEGDGYIYVVIEHQSTPDAHMAFRLMCYATAA
                     MQRHLDAGHKTLPLVIPMLFYHGAKSPYPFSLCWLDEFGDPALARQLYATAFPLVDIT
                     VVPDNEIMQHRRIAMLELVQKHIRQRDLMGLVERLAVLLITGNANDSQLKALFNYLLI
                     QHGSTPRFGKFIREVARCVPQHKERLMTIVDRIRESGRRKGKREGVQQGIQQGIHQGK
                     QEEALRIAHTMLEQGIEREMVLMITGLSDEEIKAKRH"
     gene            complement(45771..46673)
                     /locus_tag="OPV72_000400"
     CDS             complement(45771..46673)
                     /locus_tag="OPV72_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HCR9912801.1"
                     /translation="MGSTRKGMLNVLIAAVLWGSSGVCAQYIMEQSRMSSQFLTMIRL
                     LFAGLILVTFSFMHGDKIFSILKNRKDALSLLIFSVVGALTVQLTFLLTIEKSNAATA
                     TVLQFLSPTIIVAWFALARRTRPGILVLTAILTSLIGTFLLVTHGNPTSLSISSGALF
                     WGIASAFAAAFYTTWPSRLIAQYGTLPVVGWSMSFGGLILLPFYAKEGTHFAVSGSLI
                     LAFFYLVVIGTSLTFSLYLKGAQLIGGPKASILSCAEPLSSALLSLLLLGISFTLPDW
                     LGTLLILSSVILISLDSRRRARAA"
     gene            47179..47874
                     /locus_tag="OPV72_000401"
     CDS             47179..47874
                     /locus_tag="OPV72_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC family protein"
                     /protein_id="HCR9912802.1"
                     /translation="MEERMLMFPYILNLLAAMLLGALIGAERQWRQRMAGLRTNALVA
                     TGAAVFILSSMTTSPDSPGRIAAQIVSGIGFLGAGVIMREGMNVRGLNTAATLWCSAG
                     IGVLCGLGQFKNALAATIIILCANILLREAAQRINQLPVSAEAEKRYILKVTCNKEDE
                     SAVRQWLLNIVKEAAICLQGLGSVPAQEQGYKEIRAELVGHADYRKTRELIISRIGDN
                     DNITAIHWSIDSQ"
     gene            48094..50820
                     /gene="mgtA"
                     /locus_tag="OPV72_000402"
     CDS             48094..50820
                     /gene="mgtA"
                     /locus_tag="OPV72_000402"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HCR9912803.1"
                     /translation="MTDMNIENRKLNRPASENDKQHKKVFPIEAEAFHSPEETLARLN
                     SHRQGLTIEEAGERLKVYGRNEVAHEQVPPVLVQLLQAFNNPFIYVLMALAGVSFITD
                     YWLPLRRGEETDLTGVLIILTMVSLSGLLRFWQEFRTNRAAQALKKMVRTTATMLRRG
                     PGNIGAVQEEIPIEELVPGDVVFLAAGDLVPADVRLLASRDLFISQLILSGESLPVEK
                     YDVMADVAGKDSEQLPDKDKSLLDLGNICLMGTNVTSGRAQAVVVATGSRTWFGSLAK
                     SIVGTRTQTAFDRGVNSVSWLLIRFMLIMVPVVLLINGFSKGDWVEASLFALAVAVGL
                     TPEMLPMIVSSNLAKGAIAMSRRKVIVKRLNAIQNFGAMDVLCTDKTGTLTQDNIFLE
                     HHLDVSGVKSSRVLMLAWLNSSSQSGARNVMDRAILRFGEGRIAPSTKARFIKRDELP
                     FDFVRRRVSVLVEDAQHGDRCLICKGAVEEMMMVATHLREGDRVVALTETRRELLLAK
                     TEDYNAQGFRVLLIATRKLDGSGNNPTLSVEDETELTIEGMLTFLDPPKESAGKAIAA
                     LRDNGVAVKVLTGDNPVVTARICLEVGIDTHDILIGTQVEAMSDAELASEVEKRAVFA
                     RLTPLQKTRILQALQKNGHTVGFLGDGINDAPALRDADVGISVDSAADIAKESSDIIL
                     LEKDLMVLEEGVIKGRETFGNIIKYLNMTASSNFGNVFSVLVASAFIPFLPMLAIHLL
                     IQNLMYDISQLSLPWDKMDKEFLRKPRKWDAKNIGRFMLWIGPTSSIFDITTFALMWY
                     VFAANNVEAQALFQSGWFIEGLLSQTLVVHMLRTQKIPFIQSRATLPVLLTTGLIMAI
                     GIYIPFSPLGAMVGLEPLPLSYFPWLVATLLSYCLVAQGMKRFYIKRFGQWF"
     gene            50842..50934
                     /gene="mgtR"
                     /locus_tag="OPV72_000403"
     CDS             50842..50934
                     /gene="mgtR"
                     /locus_tag="OPV72_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein MgtR"
                     /protein_id="HCR9912804.1"
                     /translation="MNRSPDKIIALIFLLISLLVLCLALWQIVF"
     gene            51135..51613
                     /locus_tag="OPV72_000404"
                     /pseudo
     CDS             51135..51613
                     /locus_tag="OPV72_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462661.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(51936..52616)
                     /locus_tag="OPV72_000405"
     CDS             complement(51936..52616)
                     /locus_tag="OPV72_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase family protein"
                     /protein_id="HCR9912805.1"
                     /translation="MSTPANFNGQRPAIDANDAVMLLIDHQSGLFQTVGDMPMPELRA
                     RAAALAKIATLCNMPVITTASVPQGPNGPLIPEIHANAPHAQYVARKGEINAWDNADF
                     VQAVKATGRKTLIIAGTITSVCMAFPAISAVAEGYKVFAVIDASGTYSKMAQEITMAR
                     VVQAGVVPMDTAAVASELQRTWNREDAAEWADVYTKIFPAYQLLIESYTKAQEVVKNN
                     ELLDSQRA"
BASE COUNT        12081 a        13253 c        14573 g        12887 t
ORIGIN      
        1 cgggcctggc tatcccaacg atacgctaaa gcctgaaagt gaagcccgtg tgcagtatga
       61 tgacgagcat cgtctcttat caggacatcc catgaaacaa atcaccttta cgccgcgcca
      121 tcaccagctt accaacacca atacctggac acctgacagc cagtggctgg tctttgatgt
      181 gcggccttca ggcgcgtcat ttacgggcaa gactattgag cgtgtcaatg tgcataccgg
      241 cgacgtggag gtgatttatc gcgccgtgca gggcgcgcat gtcggtgtgg tgacggtgca
      301 tcctgccgac aattactatg tgtttattca tggccctgaa aaccctgatg agacgtggca
      361 ttacgatttc caccaccgtc ggggcgttat tgcaacgccg gggggcgtga ctaacctcga
      421 tgcgatggat attactgcgc cgtatactcc cggcgcgctg cgcggcggca gccacgtcca
      481 tgtatttagc ccgaacggcg agctggtgag ttttacctat aatgaccacg ttctgcatga
      541 gtgcgatccg gcgctggatc tgcgtaatgt cggcgtggcc gcgccgtatg ggccggtaac
      601 ggtgccagtt cagcatccgc gcgaatacag cggtagccac tggtgcgtac tggttagccg
      661 cacgacgcct gcgccgagac ctggcagcga tgacattaac cgcgcctatg aagagggctg
      721 ggtgggcaac cgccagatcg cctttattgg cgatacgctg tcgctgacgg gccaaaaagt
      781 cccggagttg tttattgtcg atttaccgtg tcatgaaaac ggctggaaac aggcaggcga
      841 cacgccgctg acgggaaccg aatcaacaat gccatcgccg ccgttgggcg tagttcagcg
      901 gcgtcttacc tttactcacc agcgtgttta tcctggactc actaacgaac cacgccactg
      961 ggtacgcagt aatccgcagg cgacggcgat cgcctttttg atgcgggacg ataacggcgt
     1021 agcgcaactg tggctgatat cgcctcaggg aggcgagccc cggcagttaa cgcatcatgc
     1081 gaccggcgta cagtcagcgt ttaactggca tccgtcgggt aaatggctgg gactggtgct
     1141 ggaaaatcgg attgcctgct gcgacgcaca aagtgggaag atcgacttct taaccgccag
     1201 gcacgacaac ccgccgtctg cggacgccgt cgttttttca ccggatgggc gacacgtcgc
     1261 atggatggaa gaggtgaaag gtttccgtca gctatgggtg acggaaaccg ggcgataaat
     1321 cagggaggag gcatcttcgc cggggggatg acggcattgg tcattttcgt ctcctcctcg
     1381 cttttctcga cgcgcgatct taccgaactg tctttgcgga agatgtccca cggcagaagg
     1441 atcgtatcca tcacggcggt aaacggcata tccaggatgg ccaacgattt ggtgccccag
     1501 tttgtctcat cgttaccgat catcgtagcg ctggcgcgcg tgccaggata agtaccctct
     1561 ttaccgccgg tgtgcgacat gacgcttgaa caaccgccta ataaaagcat cccattccat
     1621 attatcagcg ttaaccacac gttttttatc atcactcatt catctgttgg ttgtcgttat
     1681 ttgcatgatg agttatagcg atccgttgct aaaaataaca tcaccagtac gtggcactgt
     1741 ggcggtaatc gcactttaac aatcagtgct gtcccaacca gtctatgcaa tagccaataa
     1801 actgcaaaaa aaagtcggat taaaatactt gaaaagtacg tattcagacc catttataag
     1861 acgtagtgaa tagaagggca cgcctgatgg gtgttctggc aatcctggcc tgtccatgat
     1921 ggaaggtctg acattctcgc tgatttcagg agtttatgat tatgcgtaac tttgatttat
     1981 ccccgctgta ccgttctgcc attggttttg atcgtctgtt taacctgctt gaaaataacc
     2041 aaagccaaag taatggcggc taccctccgt acaacgttga gctggtagac gaaaaccact
     2101 accgcatcgc cattgccgtt gccggtttcg cggaaagcga actggagatt actgcccagg
     2161 ataatttact ggtggtaaaa ggcgctcatg cggacgagca gaaagaacgt acttacctgt
     2221 atcagggcat tgccgagcgt aactttgagc gtaagttcca gttagcggag aacattcacg
     2281 ttcgtggcgc aaacctggtc aacgggctgc tgtatatcga actggagcgc gtgattccgg
     2341 aagcgaacaa accgcgccgt atcgaaatta actgattccg tcgggtcgcg ttgcgcggcc
     2401 tgtcatccca tgctcgccgt cagggagcat attcgcacgt aaagtgtgaa ggtaaaaact
     2461 cgcttcttag aaggagaaat gattatgcgt aactacgatt tatccccact gttgcgtcaa
     2521 tggatcggtt ttgacaagct ggccaatgcg ctgcaaaaca gcggcgaaag ccagagcttc
     2581 ccgccctata acatcgaaaa aagcgacgat aaccattatc gcattacctt agcgttagcc
     2641 ggtttccgtc aggaagatct ggatattcaa ctggaaggca cgcgcctgac ggtgaaaggc
     2701 acgccggaac agccggaaaa cgagcccaaa tggttacatc agggcctggt catgcagcct
     2761 tttagcctga gctttacgct ggctgaaaat atggaagttt ccggcgcgac gtttaccaac
     2821 ggcctgctgt atattgattt aacccgtaac gagccggaaa ccattccgcc gcagcgtatc
     2881 gccattaacg aacgctccgc attaaatagc taataagctc cttgccttgc cccgccagag
     2941 atggcggggc ttttttgtgc cacgaaaaag ggtaagacgt tgccgaagtc aggacgtctg
     3001 tgcggttttg taatatgaga atgtgcgcca tgctgtatat atgccttaac ggttcagtca
     3061 taatccctat aaattgaaat gttactcaca gggaagagaa gatgagatga gtgatatcgc
     3121 attgacggtc agcgttctgg cgttggtggc ggttgtcggt ttatggatcg gcaacattaa
     3181 agtgcgcggt gtcggctttg gtattggcgg tgtgttgttc ggcggtatta tcgtcggcca
     3241 cttcgtcgat caggctgggg tgacgctgag cggcgatatg ctgcacttta tccaggagtt
     3301 cggcctgatc ctttttgttt ataccatcgg catacaggtg gggccggggt ttttcgcctc
     3361 gctgcgcgtt tccgggctac gtctgaatct gtttgccgtt ctgattgtga ttatgggcgg
     3421 gttggtcacc gcgattctgc ataaaatttt cgctattccg ctgccggtag tgctggggat
     3481 tttctccggc gcagtcacca atacgcctgc gttaggggcg ggtcagcaaa tcctgcgcga
     3541 tctgggaacg ccagtggatc tggtagatca gatggggatg agctatgcga tggcgtatcc
     3601 gtttggcatc tgcggtattt tgctcaccat gtggctgatg cggctgattt ttcgcgttaa
     3661 cgtcgaggcg gaggcgcaga agcacgaatc ctctctcgct aacggccatt cattaattca
     3721 gacaatgaat atccgtgtcg agaatccgaa cctcaataat atggctatcc aggatgtgcc
     3781 gatcctgaac agcgataaaa tcatttgctc acgcctgaaa cgcgatgaca cgctgatggt
     3841 gccgtcgccg gggacgatta tccaggcagg cgacctgctg cacctcgtcg gccaacctac
     3901 cgacctgcat aacgcgcaac tggtgatcgg taaggaagtg gacacctcgt tgtcgacgcg
     3961 cggcacggat ttacgtgtcg agcgtgtggt catcaccaac gaaaaagtgc tcggcaaacg
     4021 tatccgcgat ttgcacttta aagagcgtta tgacgtggtt atctcccgcc ttaaccgcgc
     4081 gggcgttgag ctggtcgcca gcagcgacgc tagcctgcag tttggcgaca ttctcaatct
     4141 ggtggggcgt cctgcctcga ttgatgcggt agccaatgtg gtcggcaacg cgcagcaaaa
     4201 actccagcag gtgcagatgc tgccggtgtt tatcggcatc ggattagggg ttctgcttgg
     4261 gtcaatcccg ttgtttgtgc cgggattccc ggtcgcgtta aaactggggc tggccggcgg
     4321 gccgttgatc atggcgctaa ttttggggcg tatcggcagc atcggtaagc tgtactggtt
     4381 tatgccgccg agcgccaacc tcgcgctgcg tgaattaggc atcgttttgt ttctggcggt
     4441 cgttggactg aaatccggcg gcgattttgt cgatacgctg acacagggcg aaggattaag
     4501 ctggattggc tacggtattt tcatcaccgc tattccgctg attaccgtcg gtttgctggc
     4561 gcgaattttt gccaaaatga actacctgac gctgtgcggg atgctggccg gttcgatgac
     4621 cgatccgcca gcgctggcat ttgccaacaa tcttcatgcc accagcggcg cggcggcgct
     4681 ctcttacgcg accgtctatc cgttagtgat gttcctgcgt attatcacgc cacaactgct
     4741 ggcggtgatt ttttggggaa tgggttagcg cctgatggcg cgttgcttat ccggcctatg
     4801 cactgtgtta aatccaggct ggataacgcg cgccgcaccg gtcacacttc tgctcttctt
     4861 cttatctctt tcctcaatga acgtgctaat cagcgtaatg gcaacgagca taattccaat
     4921 tttttcagtt agttatcaat cttcatcgcc ttttttttcg tcgcaacggg tagtttttca
     4981 gcttttaatt cggcaataat gcctttcctg gcggtggcgc tgaaaaaggt cgcaactgaa
     5041 atgaaaaata gcggcaatga gcgcggttgc gccgaaacac gtcaccagtg aactacagtt
     5101 attttgcaat aagattccct tgctgcggga taatgtgaag catatcagca acaacgtgag
     5161 tggtattctg aaaacgaacg ggaatacata agaacgtaaa aggagtcgtc atgaagattt
     5221 cccgcctcgg agaagcgccg gattatcgct tctcactggc aaatgagcgc acctttctgg
     5281 cgtagattcg cacctcgctg ggatttctgg cggcaggcgt cggtcttgat cagctcgccc
     5341 cggattttgc cacgccggtg atccgtgaac tgctggcgct actgttgtgt ctgtttgcgg
     5401 gcggcctggc gatttatggc tatctacgct ggttacgtaa tgaaaaagcg atgcgcctga
     5461 aagaggattt gccttatacc catagcctgt tgatcatcag cgttattttg atgattgtcg
     5521 cggtgatagt gatgaggctg gtactgtatg ccggatagtc gtaaagcccg tcggcagaac
     5581 gatccgggac tgcaaccgga gcgtacgtcg ctggcctggt ttcgcacgct gctgggatac
     5641 ggggcgttaa tggcgttagc cgtcaggcac tactggcatc aggcggggtt cttgttctgg
     5701 gtgtcaatca gcgttctggc gatagtggcg gtgattcttt ggcgttatac cctgagtcgt
     5761 aatttgatgg atgtcgcgca tagcgatttt tccgaaactc atgtcatgcg tgacaaattt
     5821 ttgatctccc tcgcggtgtt gtcgctcgca atcctgtttg ctgttaccca tattcgccaa
     5881 cttattgcat ttatcgggga ttttatatga caggacgtca ggacattgtc gtgagtaatg
     5941 accagattca ggtcgtcgta aatcgccaga atagccagcg ccctcagcaa ctgtaccgta
     6001 acttacaacg gctcggcatt cgcaatgtcc attttatccc attgttggaa catgaccgga
     6061 acggaatgtt gaccgaggat tcattgtgtt cagcagactg ggggcggttt ttaaatagcg
     6121 tatttgatat ttgggtacgt gaagatattc agcgtatctc ggtccgcctt tttgatgaga
     6181 cgctacagca gtggtgcggc ggcaggaatg gcgctaaaac gccggacaag gcgccgctaa
     6241 gcgctgaatg tcagaagtgc tctttattac gattttgcgg cggcggatgc cctgagcatc
     6301 gggatagcca ggggaaaaat cagctttgcg agggctacca gacctttttt aactactcct
     6361 cgccgcatat gcgggtgatg cgggatttac tgaaacagca tcgctcgccg gaggagttga
     6421 tggcgatgct gcgttaacgt cacaggcctg ataagcgtag cgccatcagg cgatggcgtg
     6481 ccggatggcg ctgccgtctt tccggcacta agcgagtatt agcgtccttt tgccaggtat
     6541 tgttccattt catcctccgg caccatgccg cccccggttg cccatatcag atgcgtcgcg
     6601 ttgccgagct gcgtctgact gaatccatgc ctttgctgat acgcgacgga ggcgcaaatg
     6661 cgctgtggcc cggccatccc cgccagagct gatggctcca gtcgaattcc ttcctcctgc
     6721 gccagccagc ccagcatgtc atacattgtt tgatcgtcta aggtatagag gccgtcaagc
     6781 agacgctcca ttgcccgacc aacaaagccc gaagcgcgac ctaccgccag gccgtcagcc
     6841 gccgtcaggt tatcaatacc gatatcttgt actgagatgg catcgtgcag accggtataa
     6901 acgccgagta acatgcaggg tgaatgggtc ggttcggcaa agaaacagtg gacgttgtcg
     6961 ccaaacgcca gtttcaggcc aaaggcgacg ccgccagggc cgccgccaac gccgcacggc
     7021 agataaacaa acagtgggtg gctggcgtca acgacgcgtc cctgctgcgc gaattgcgct
     7081 ttcagacgct gacccgctac cgcatagccc agaaatagcg tgcgagagtt ttcatcatcg
     7141 ataaagaaac agtttggatc ggattgcgct gctttacgac cctgctcaac cgccacgccg
     7201 taatcatctt cgtattccac gaccgtcacg ccgtggctac gcagcttcgc ctttttccag
     7261 gcgcgggcgt cggcagacat atgtaccgtc actttaaaac cgatgcaggc gctcatgata
     7321 ccgatcgata gccccagatt gccggttgaa ccgacggcga tactgtactg gctgaagaat
     7381 tgtttaaatt ccggcgaaag caacacgcta tagtcatcgt cggtggttaa cagacccgcc
     7441 tccagcgcca gtttttccgc gtgcgttagc acctcgtaga tgccgccgcg cgctttaatg
     7501 gaaccagaga ttgctaggtg actgtctttt tttaatagca tttcaccgtc gatcgtttgc
     7561 ccatactctt tttccagccg tttttgcatg gccggaatag cgaccacgtc agattcgatt
     7621 atgccgccag cggcagcggt ttgcggaaac gcttttgcca gatacggcgc aaagcgcgcc
     7681 agacggtcat gggcggcgtt tacgtcctgc tccgtcaggc cgacatacgg tagaccttgt
     7741 gcaagagagg tggcgcccgg gttaaaccag gtggtttctt tgagggcgac cagatcctcg
     7801 accaaaggat accgggcgat gagctttagt atgttttcca tagtacgtct ctttacgatc
     7861 agatgataaa ggaaagcagg aatgtgccag ccagtgcaac gacagatgcg ataaacgtgg
     7921 ccgtcgtata gtatttaaac gtttcattca gcgtagcgcc gcaatactgc ttgaccagcc
     7981 agaacaggga atcggtcacg atcgtgcagc caatggtgcc ggaaccgatg gcaatagcga
     8041 tgatctccgg gctaacgtca ggatagagcg gcagcatggg cgcaacaatc gcggtggcgc
     8101 ccatcatcgc caccgtcgca gagccgaccg ccgcgtgcag aatcagcgct accagccatg
     8161 ccagcagaat cgggtgcata tgcatatttg agaggatcac cgccagcgtg tccgccagtc
     8221 cgctactttt gagaatggcg ttgaacgcgc cgcccgcgcc gataatcagc aggatgttcg
     8281 caatggcgcc aaagccgttt tcggtgtggg taagtagcgc gctcataccc atatgctggc
     8341 gcagaccgag tatgtaatac gccacaaaga cagcgataaa catcgcggtg atcggattac
     8401 cgataaactc cagcagcgta tacaacgtgc cgtctttcgc catattcagt tcagcgacgg
     8461 ttttcaccag catcaggcca atcggcagca gaacggtaaa cagcgttgcg cccagcgacg
     8521 gcagggtgtt ttcggcacgc acttcaagat ccgcaaactc tgtcggtacg ggcttgaacg
     8581 gcagacgatt acccagaaac tttaagaaca gcgggccgcc gaccaatgag gccatcagtc
     8641 cgaccagcag accgtagaca atcaccgagc cgatatccgc ccccagttta tttgcgacaa
     8701 acagcgcagc cggatgcggc ggtaccacgc aatggacggc catcagcgcg gtacacagcg
     8761 gaatggccag cttcagcagc gaggtatggg tctttttagc gatagaaaac gccagtggga
     8821 tgagcaacac gacgcccact tccacgaaca acgtgattcc gcaaatcagc cccaccagta
     8881 ccatgatcac gtcagcagag agccagcggc agcgctggag cgtaagcccg atgcgttccg
     8941 ccgcgccgga aacctccatc attttgccga ggatggtgcc aagaccgata acggcggcca
     9001 gaaaaccgag cgtaccgcct attccgtttt ctatcgccgt gaccatctcc agcggcccta
     9061 tgcccatcat cgcgccgaca aagaaactgg cgagcagtaa cgccaggaag gggtggaatt
     9121 taaacttcac gatggtcaat acgattaaca cgatgctgat cagcagcgtg ctcactaccc
     9181 agatttgagc gtgcatatct cacctaccct gtgattaatc tgttcttatt ggacagaaaa
     9241 acagcacacc ctgacaaacg atataatttg ccattcacat gatgtaaatt gaatcaacta
     9301 tgtgatttcc atctaatatt gcctttattt tgcgatatgg ttcattttac ttcatctatg
     9361 tgcggatttt ttcagcgcgt ttttttacac ttcgggaaat taaaagatga ctgaggttgc
     9421 catggaaccc cttcgcgata cccgaaaccg cttactcaac ggctggcagt tatccaaact
     9481 ctatactttt gaagtcgcgg ccagacacca gtcctttgct ctggcggcag atgagctgtc
     9541 gttaagcccc agtgcggtaa gccatcgtat caatcaactg gaagccgagt tgggaatcca
     9601 gctatttgtc cgctctcacc gtaaagtgga gcttacccat gaaggcaaac gggtattctg
     9661 ggcgctgaaa tcgtcgctgg atacgttgaa tcaggaaatc ctcgatatca aaaatcagga
     9721 actgtccggc acgttgaccg tgtattcacg cccctctatc gcccagtgct ggctggtgcc
     9781 cgcgttgggg gactttaccc gtcgctatcc gtcaatttct ctcactatgc tgaccggcaa
     9841 cgataacgtt aacctacagc gtgccggcat tgacctggct atctattttg acgatgcgcc
     9901 gtcggcgcag ctcacgcacc attttttaat ggatgaggcg attttgcccg tttgcagccc
     9961 ggattacgcc cgtcgtttcg ccttgcagga caacctgaat aacctgcggc actgtacgct
    10021 cttacacgac agacaggcgt ggagtaacga ttctggcacc gatgagtggc acagttgggc
    10081 gcagcatttt gcggtaaatt tgccggattc atccggcatt ggcttcgatc gttctgattt
    10141 agcggtgatt gccgcgatga accatattgg cgtggcgatg ggacgtaaac gactggtgca
    10201 aaagcgtctc gacagcagtg aactgattgc gccttttggt gacatgagac tgaaatgtca
    10261 tcagcattat tatgtcacca ctctgcctgg caggcagtgg ccgaaaatcg aggcatttat
    10321 tcgctggttg caggaacagg tgtgaagatt tattacgctt tgccgctaca cctgccggga
    10381 gtgaatatgc taaatacgtg ctatcaccgt ggtaaaaatt ttagggggcg tcgtgtttaa
    10441 accgcttatt gcctctctca tactgaccag cgcggtcgtc tatgcgaaac cgatgccttt
    10501 gacggcggcg cgctatgcgc agcagcttgg cgttgggatg gatgttgact gggcgcgaac
    10561 ggaacggggt attcgcgagt ttgatccgtt ggtcgtgcgg gattttaagg caaaagggtt
    10621 aacgcatgtc cgtattcgtg tggcaggcgc gccgacggaa gcgcgcctca tccatttgcg
    10681 taagctggta gaggcctgcg aatactatgg cgtcataccc attattgcct atcaggcgga
    10741 tgcgtataaa accgatccca gcgccagcca tgaaaaggag ctgatcaact ggtggagcgt
    10801 ggtcgcgcgc tattttggtc agacatcccc gcttctgggg ttcgatctca tttatgagcc
    10861 tgccgacaaa cttaatcata atatggcgtc gctgaatcgc gtatatgaca aaaccatccg
    10921 cctgattcac gccattgacc cacagcggat gattttcgtt gccccccgca tgcgcgccgc
    10981 gccggaggat ttatcggcgc ttaaactgcc ggcgcaaagc cagaactatg tactggcgga
    11041 gtggcacatc ttcccgtggg gacccctgaa aagcggcggt aaatatccgt ggacgtcagg
    11101 cacgacggcg gaaaaagcgg cgattcgggc acggattaat gccgcggttc gctggcagca
    11161 taagaccggc catgcaagct gggtgggcgg atgggcgccg ggagagtcga taaaaatgac
    11221 gccgatcgct tcacagttcg cgtttgcccg ttttatggcc tgcgagctga aaaaagcgca
    11281 tattccgtat gcgataaacg cggacactca gttttatgac ggcgaagaag gagcgtggcg
    11341 tccggcgcag gagcccctgc tcaatgcgat gatcgcgccg gaatgtgaaa cgcccggcaa
    11401 aaagccgggc gaggggaatg ttaaaccgtc tgtccctgat gcgatatccg tgacgccagc
    11461 ggcagccagc acgccaagat cagcaatccc ataagggtca tcagcaatcc cagactgccc
    11521 tgaccggttt gcggcagcat tgccgaaagc cacgccagta cgccggaacc aatattttgc
    11581 agcccgccga ccagcgcgcc agcggtgcct gcgaggaacg gaaacggctc catcgcgccg
    11641 ctggtggcca gtggaaataa catcccggcg ccgaagaaaa acagcgcagc ggggatgagt
    11701 agcgtccaga cgttcatcac gccaaaccag ccgggaatcc acatcataag gcctgccagc
    11761 agacagcaaa taactgactg ccacatcagg gctgagaagc gtttattcgg gcgtccggca
    11821 aaccaggcgc cgaagaacgc cgccggaatc ggcagaataa acagaatgct taccaccata
    11881 ctgctgagac ctaatactgc tcccatcagc acgccggaac aggcttcaaa gaccgcaatg
    11941 ccagccagcc cgccgattag catcagcagg taacagttaa atgcgccgtt gccaaacagc
    12001 gtcttatagc tggcgatcag ccgcgtacgc ggcgcgccgg cggggcgggt ttccggcatc
    12061 cagcgcgcca tgctgaaggt gacgccagcg caaagcacca gcaggaaagc gtaacacgcg
    12121 cgccagttcc acagggtatc cagcaggccg ccaatcagcg gcgctaacag cgggctgacc
    12181 agaatcccca tatttaacag gctattggca tgacgaagtt gcgttccttc atacagatcg
    12241 cgcgggagcg ttctcgccat tactccgcca acgccggttc ccatcccttg catggcgctg
    12301 gcggcaatca acaccgtcaa actatgcgtg gtcatggcga tcagagtcgc taccataaaa
    12361 atagacatgc cgacgaggat taccgggcgg cgcccaaccc ggtcggaaag cgggccgtaa
    12421 aacagttgcg agacgccgta ggtcaggagg taagcagcca ttacgctctg gacggcgcct
    12481 tcccggacgt ttagcgcttg tgccatatcg gcgatggcgg gaatataaat ggtttgcgcc
    12541 atctgcccta cggccaccag taacaccaac atcaacaaca aattgacgtt tctctgcctt
    12601 ttcatttcgc tgattacttt tcaaaaaaag aaaaaataag aataacttgc tgcgcattcc
    12661 cataaatgcg agaggaatct atcacaccag aaaaagaagg ccagacagca accagcaatg
    12721 gcagacgaag gaacggcagg atatgtaaac aaaagcggca acaaatgttg ccgagaatgt
    12781 gttacgtctg cagctgttat tgggcaatca tgacagacgg agtaaaatcg ccccgagggc
    12841 aatcccgccc gccgccacca gacgtagccc ggccactttc tctttaagca acagccaggc
    12901 tatcagcgcg ccgaataaaa tcgacgtctc acgcagcgcg gcgaccaccg ccagcggcgc
    12961 ctgggtcatg gcccatagcg ccagcccata agatcccata gtgccaatcc cgccaaaaat
    13021 gccttttttc cactgttgcg ccagataacg cgacgcttcc cgccgccgcg caatcatcgc
    13081 ccaagttaac aggcaggcgc cgttgagaaa aaatgaccat agcgtatagc ccagcgccgt
    13141 ttcggagagt cttacgccgg tcccgtccac cagcgtatat ccggcaataa aacaggcgtt
    13201 agttaatgcc agcacgacac cacgttgaga gctggcgcgg ccattacagg ccatcccaag
    13261 tatcgccatg cagatcactg cgatgccgac ctaggccatc gacgacaggc tgtcgccaag
    13321 aaacagaacg ctaatgagcg ccaccagcag cggcgcggtg ccgcgcataa gaggataggt
    13381 ctggctcatg tccgagacct gataggtttt cgccaccagg acggtataca ccacctggag
    13441 cgcggtagag gccgctaaaa aagggatact ggcgtgagct ggctgcggcg agaagggcaa
    13501 aaggatcaat gccatgaccg ccgcggaacc gctgacgccg atcgcggcgt agagcttatc
    13561 gtttcccgct ttgacaatgg cgttccagct ggcatgtagc agcgcggcga acagcaaaat
    13621 gcagaaaacg gaaagggtca tagcatcagg cgtcgttgag ggtgtcataa aaacgtaaca
    13681 tacccgggaa gcgaaagacc agcggataag gtgaaagggg agcggttgcc cgctcccctt
    13741 cggtgcggct tgaatctgaa ttacttaagg tatttcagaa cagcatcaag cagttgcagt
    13801 gctgcaacaa tgagtttcag gataagaatg gtgatatcca ctacgctcat acgcgtctcc
    13861 tgtggttaag gagcactgcc agccgacgta cctttccgct gcctgttgcc agctgttgcg
    13921 cacgcgatcc cttttgcgag gaatagtgtg cgtgttgaca taacacagtg tgctcacgag
    13981 ggggttaagg cgctgacggc accacccgtt tcagccagga cttcgttgcg ccggtttacg
    14041 atgcggcccc cgcataacac attgtgtcaa agacattata gttaagtgct gtataaatga
    14101 acagtaattt atagacagaa cggagcttct gatccatact caaattcatc aaaattcgcg
    14161 ccgaaattgc gcgttctgca cagaacgcgt atacttctgc tgttgacata acacagtgtg
    14221 cttcgcggct accacccgca ttacgctgta agaacctcgc ttcggcgagg ttttttgttt
    14281 tcaggcattg tgaaacgcgt gatcatcaat cccggcgatt accggagggc gctacgctta
    14341 tcacgcctat actcaaagcg tgtaaattcg tagaaaaatg tgatcgctga cgcatttttg
    14401 tgcagatgaa aatttttccg ttgtcatgct gaaagcgctg tgcttgtata aaacgtgtta
    14461 ataacaaaca gacaaggccc ctaatgaacc cttccatgct gaacgcgacc ctactaacaa
    14521 ctgcgccatc tcgcgcagtg gtcgtcgtgc gtgtggtggt ggtcgtcggc aatgcgccgt
    14581 agggtccgga acacacacga ttccaaaacc ccgccggcgc aaaccgggcg gggttttttg
    14641 tttaagacac cttcccggaa cgtcggctca gaataaaagg aatggagcat ggcaagttcg
    14701 ggcacaacat ctacacctca gcgctttacg ggcgcggaat ttatagttca ttttctggag
    14761 cgccagggga ttcgtatcgt caccggcatt cccggcggtt cgatcctccc cgtttacgac
    14821 gcgttaagcc aaagcacgca aatccgtcat attctggcgc gccacgaaca aggcgcgggg
    14881 tttattgcgc aggggatggc gcggacggag agtaaacctg ctgtttgtat ggcctgtagc
    14941 gggccaggcg cgaccaatct ggtcacggct attgccgatg cgcgcctgga ttccattccg
    15001 ttaatctgca ttaccgggca ggttccggcg tccatgatcg gtactgacgc gtttcaggaa
    15061 gtggatacct acggtatctc tatccccatc accaagcaca actatctggt cagaaatatc
    15121 aatgagctgc ctcaggtgat gagcgatgct tttcgtctgg cgcagtcggg gcgtcctggc
    15181 ccggtgtgga tagacgttcc taaagatgtg cagacggcga ccattgagct ggatgcgttg
    15241 ccgtcgccgg cggaaaaatc acccccgccg gagtttagcg cggagagtat ccgcgaggcc
    15301 gccgcaatga ttaacgcggc gaagcgtccg gtgctgtatc tgggcggcgg cgtgatcaat
    15361 gcgccgacac gcgtgcgcga actggcggaa aaagcgcaac tgccgacgac aatgacctta
    15421 atggcgctgg gaatgctgcc taaggcgcat ccgctgtcgt taggaatgct gggaatgcac
    15481 ggcgcgcgca gtaccaattt tattctgcaa gaggccgatt tactgattgt tctgggcgcg
    15541 cgttttgatg accgggcgat tggcaaaacg gagcagtttt gtccgaacgc caaaatcatc
    15601 catgtggata tcgatcgcgc cgagttaggc aaaattaagc agccgcatgt ggctattcag
    15661 gcggatgtcg atgatgtact ggcacagtta attccccata tcgaggcaca gccgcgggaa
    15721 gcatggcatc agttggtggc ggacttgcag caagaattcc cttgcggtat tccccaggaa
    15781 aataacccgc ttagtcacta tgggctgatt aacgcggtcg cagcctgtgt ggacgacaac
    15841 gcgattatta ccactgacgt aggtcagcat cagatgtgga ccgcgcaggc ttatccgctc
    15901 aaccgtccgc gtcagtggct gacttccggc gggctgggca ccatggggtt tggtctgccc
    15961 gcggcgattg gcgcggcgct ggcgaatccg ggcaacaagg tgctgtgttt ttccggcgac
    16021 ggtagtttga tgatgaatat tcaggagatg gctaccgcca gcgaaaacca gttggatgtg
    16081 aaaatcatcc tgatgaataa cgacgcgctg ggactggtgc atcagcaaca gagtctgttc
    16141 tataaacagg gcgtttttgc ggcaacctat ccgggaagca tcaactttat gcagattgcc
    16201 gccgggtttg gtctggacac ctgtgatttg aataacgaag ccgatccaca ggcggcgttg
    16261 caggctatca ttcgtcgtcc tggaccggcg ttgatccacg tgcgcattga tgcagaagaa
    16321 aaagtgtatc cgatggtgcc gccgggtgcg gcaaatacag agatggtggg ggaataagcc
    16381 atgcagaaac aatcacatga taacgttatt ctggagctga ccgttcgcaa ccatcctggc
    16441 gtgatgaccc acgtctgcgg gctgttcgcc cgacgcgctt tcaacgttga gggtattctc
    16501 tgtttaccga ttcagggtag cgatcagagc cgcatctggc ttctggtcaa tgacgatcag
    16561 cggcttgaac agatgataag tcagatcgat aaactggaag acgtggcgaa ggtggtacga
    16621 aaccagtccg atcccaccat gttcaataaa attgccgtct tttttgagta agttattcac
    16681 tttccgaatc aggcgtgatg actttgacgg aaccattccg acagtgaacg gcataatctg
    16741 tcggtaatgg gcgatcgcta atcaggacat caaaggcaga aagcggacca atgctggcag
    16801 gcgcgacctc atcaaacagg gcgtgacgcg ccagcaaaat tttgcgcaga ccgcgctcca
    16861 tcgctttacg tttggcggca agatcatccg ggttaaacca gctcacgcca aaatgttcat
    16921 gtacgccgct ggcggaaata aacactttgc gcggattaag cgaatccagc gccgaaggat
    16981 tattggcatc ataaaaggca tcgctcttgg cccgataggt gccgccgcac agaatcgctg
    17041 tggcattagg cttttcattc agcgcgataa atacccgatg cgagtagcaa atcccggtaa
    17101 aggtaatatc atccggtatc atgctgatga ctaatggcat ttccggaccg ttatcaaaaa
    17161 aaaccagatc gttttcacgc accaggccgg cggccaagat cgcaacggga aggtcgtccc
    17221 gatgatgcgt ctttttcgcc ggcagcggca tattggttga agacgcaggc ttatttacca
    17281 tgacgatata gccgccgagc agcgtcagcg gtaaagggtc atcatcctgg ctgagatcgc
    17341 ggcgaatggt catcaccgaa acttccagca tccgcgcggc gtctttcaga tggattcgat
    17401 cggtcttttt cagtaactcc atcaagcgtc ggatacgttc tttttgcttg gtctccattc
    17461 accctctccg caaatcatgt tgttatgttc catcagtaac atttatgtgt ttctgagaac
    17521 attacagtgt ggcactacta tacgtctggc cgtcaggaaa taaaagtggg tttattcgcg
    17581 ttttataaca ataaatagtt aattttcagt aaattgtaac cctaaaaatg atttgttccg
    17641 ccaggggttg ttcacgaagt aaatggcaaa atgatcctct aatcgcgatc atagtcacaa
    17701 atgatacgga agtaacatga taatgttatt ttaatatcat tgtcgtgtga cgatttctga
    17761 gagggagtaa aatggatatc gcggttattg gctctaacat ggtggacctt atcacctaca
    17821 ccaaccagat gcccaaagaa ggggaaactc tggaagcgcc ggcgtttaaa atcggctgcg
    17881 gcggaaaagg ggcgaaccag gccgtggcgg ccgctaagct caattcaaaa gtattgatgt
    17941 tgaccaaagt gggcgacgat atttttgccg acaacaccat tcgtaatctc gaatcctggg
    18001 ggatcaatac gacgtatgta gaaaaagtac cgtgtaccag cagcggcgta gcgccgattt
    18061 tcgtcaacgc caactccagc aacagcattc tgatcatcaa aggcgctaac aagtttctct
    18121 cgccggaaga tatcgatcgc gcggcggaag atttaaaaaa atgccagctt attgttctgc
    18181 aactggaagt tcagcttgaa acggtttatc acgcaataga atttggcaag aaacacggga
    18241 ttgaagtgtt attaaaccct gcgccagcat tacgggaatt agatatgtct tatgcctgta
    18301 aatgcgattt ctttgtacct aatgaaaccg agctggaaat attaaccggt atgccagtgg
    18361 atacctatga ccatattcgc gcagcggcac gttcgctggt agataaaggg ctgaacaata
    18421 ttattgtcac catgggcgag aaaggcgcgc tgtggatgac gcgtgaccag gaagtccatg
    18481 ttccggcgtt tagagtgaac gctgttgata ccagcggcgc gggcgatgcc tttatcggct
    18541 gtttcgcgca ttactacgtc cagagcgggg atgtggaagc cgccatgaaa aaagccgtcc
    18601 tctttgccgc tttcagcgtc accgggaaag gcacccaatc ctcttatcca agcattgagc
    18661 aatttaatga gtatctttcg ttgaacgaat aacaatcacc ctgcactgtt aaaggtagca
    18721 ctatgaacga taaaaacatc gttcagatgc ccgacgggta tctgaataag acacctctgt
    18781 tccagtttat tttgttatcc tgtttattcc cgttatgggg atgcgcagcc gcgttaaatg
    18841 atattctgat tacgcaattt aaaagtgtat tttcgctgag caactttgct tcggcattag
    18901 tacaaagcgc cttttatggc ggttattttt taattgctat tccggcctcg ctggtcatta
    18961 aaaaaaccag ttataaagtg gcgatactta tcggcctgac gctatacatt gtcggctgta
    19021 cgctcttttt tccggcgtcg cacatggcga cctacaccat gttcctcgcg gcgattttcg
    19081 ccattgcgat tggcctgagt ttcctggaaa cggcggcgaa tacctacagt tcgatgatcg
    19141 ggccgaaagc ctacgccacg ctgcggctga atatcagcca gaccttttat ccgatcggcg
    19201 cggcggcagg cattttattg ggtaagtatc tggtcttttc cgaaggggaa agcctggaaa
    19261 aacagatggc gggcatgaat gccgagcaag tccacaactt caaggtgttg atgctggaaa
    19321 acactctgga accctataag tacatgatta tggttctggt agtggtgatg gtactgttcc
    19381 tgctgacgcg ttttccgacc tgtaaagttg cgcaaaccgc gagtcataaa cgtccctcgg
    19441 cgctggatac gctacgctat ctcgccagta acgcccgctt ccgtcgcggt attgtggcgc
    19501 agttcctgta tgtgggaatg caggtggcgg tctggtcgtt cactattcgt ctggcgctgg
    19561 agttaggcga tatcaatgag cgcgatgcct caacctttat ggtctacagc ttcgcctgct
    19621 tttttatcgg caagtttatc gccaacattc tgatgacgcg cttcaacccg gaaaaagtcc
    19681 tgatccttta ctctgtgatc ggcgcgctgt tcctggccta tgtggcgctg gcgcccagct
    19741 ttagcgcggt atacgtggcg gtgctggtca gtgttctgtt tggcccctgc tgggcgacca
    19801 tttatgccgg aacgctcgat accgtcgata acgagcatac cgaaatggcg ggggcggtca
    19861 tcgtgatggc gattgtcggc gcggcggtgg ttcccgcgat tcagggctac gtggcggaca
    19921 tgttccactc gttacagctc tcattcctgg tttccatgct gtgctttgtt tacgttggcg
    19981 tttacttctg gcgcgaaagc aaagtgcgcg gcaacctggc tgaagtcgcc gcgtcctgag
    20041 gagatcaacc atgacaacac gtattacatt atggcgggag ctttttagcg agcagccgcg
    20101 tatcttgctg gaaaatgacg attttacggt tacggcgttt cgttacgcca gcggcgtgga
    20161 aggactgaaa atacaaaaca gccgcggtca tctggtgatt ctgccctgga tggggcagat
    20221 gatttgggac gtgcagtttg acggtcatga tctgactatg cgcaacatgt tccgccagcc
    20281 gaagccggct gcggaagtgg tggcaacgta tggttgcttt gctttccatt ccggactatt
    20341 ggcgaatggc tgcccgtcgc cggaagatac acatccgctg cacggcgaga tgccctgcgc
    20401 tgctatggac gacgcctggc tggagttaga gggcgacagt ctgcgcgtga ccgggcgcta
    20461 cgagtatgtg atggggttcg gtcatcatta tcaggcgcaa cctgcggtgg taatgcgtaa
    20521 atcaagcgcg ctgtttgata ttcagatgac cgtgactaac ctggcttcag tcgccatgcc
    20581 gctacagtac atgtgccaca tgaactatgc ctatgtgccg aacgccacgt tccgccagaa
    20641 tatcccggat accgcgctga agctacgcga gtcggtgcca gcgcatgtca aacccacggc
    20701 gcagtggctg gcgtttaatc aacgactttt gcagggtgaa gcctcgctgg caacgctcaa
    20761 cgagcctggc ttttacgacc cggaaatcgt gttcttcgcc gatgaactgg acaagtacac
    20821 ggataccccg gaattcagta tgatcgcccc ggatggcacc acgttcgtga cacgtttcgc
    20881 cagcgcggag ctgaattacg tgacccgctg gattctttat aacggcgatc agcaggttgc
    20941 cgcctttgcc ctgcccgcga cctgtcggcc tgaaggtttt ctcgcggcgc agcgaaatgg
    21001 aaccttgctt caactggaac cgcagcaaac ccggacgttc accgtcacga caggcattgt
    21061 ctgaccgctc aaggcttgaa cacccaggca cttatcgtta aggtaagtgc ttttgccgga
    21121 tggcggcatt aatgccttat ccggcctaca acggcacctg cccgtaggcc tgataagcgc
    21181 agcgccatca ggcatgtctt agcgccagga tgaacccatg attaccgttg cccttatcga
    21241 cgaccacctt atcgtccgct ccggctttgc acagctactg gggctggaac ccgatttgca
    21301 ggtggtcgcc gagtttggtt ccgggcgcga agcgttggca ggcttgccgg ggcgcggcgt
    21361 acaggtgtgt atctgcgata tctcgatgcc ggatatttcc ggactggagc tgctaagcca
    21421 actgccaaaa gggatggcga cgatcatgct ctcggttcac gatagcccgg cgctggtgga
    21481 acaggcgttg aacgccggcg cgcgcggttt tctctctaaa cgctgtagtc cggatgagct
    21541 gatcgccgcg gtgcatacgg tggcgacggg cggctgctat ttgacccccg atattgccgt
    21601 gaaactggcg gcgggtcggc aagatccgct gaccaaacgc gagcgtcagg tggaggaaaa
    21661 actcgcccag ggtatggcgg taaaagagat tgccgccgag ctggggctgt cgccaaaaat
    21721 ggtgcatgtc catcgcgcga atctgctgga aaaattaggc gtcagcaatg acgttgaact
    21781 ggcgcatcgc atgtttgacg gttggtaatg aacacctttt tttcccgttt aatcaccgtt
    21841 gttgcctgct tttttatctt ctccgccgcg tggttctgcc tgtggagcat cagcctgcat
    21901 ctggtagagc gcccggagct ggcggcgcta ctctttccct tcggcctgcg cctgggactt
    21961 atgctgcaat gcccgcgcgg atactggcca gtattgctgg gcgcggagtg gctgctggtg
    22021 tactggttgg cgcaggaagt tgcgctggcc catctgccgc ttttgatgat cggtggtgtg
    22081 ttgacgctac tgcccgtggc gctgacttct cgttaccgcc atcagcgcga ctggcgcacg
    22141 ttattgcttc agggcgcggc cctcaccgcc gcggcgctac tgcaatccct gccctggctg
    22201 gggcaggggg aagcggcatg gaacgcgcta ctgctgaccc tcacgggggg actgacgctg
    22261 gcccccatct gcctggtttt ctggcactat ctcaccagca ctacctggct gccgctggga
    22321 ccatcgctgg tatcgcagcc ggtaaactgg cgcgggcggc atctgatctg gtatctgctg
    22381 ctgtttatcg tcagtctgtg gctgcaactg gggttacctg ctgaactttc gcgcttcacg
    22441 ccgttctgcc tggcgttgcc gattatcgcg ctcgcctggc attatggctg gcagggcgcg
    22501 ctcattgcca cactgatgaa cgctatcgcg ctgatcgcca gccagacctg gcacgatcat
    22561 cccgtcgatt tattactttc gctgttggcg caaagcctga ccgggctact gcttggcgcg
    22621 ggcattcagc gcctgcgcga gctgaaccag tcgctgcaaa aggagctggc gcgcaaccat
    22681 cggctggcgg agcgtcttct ggagaccgaa gagagcgtac ggcgcgatgt tgcgcgtgag
    22741 ctgcacgatg acatcggaca gaccatcacc gcgattcgaa ccctggcggg cattgtgcaa
    22801 cgactggcgg cggataacgg cggcgtgaag cagagcgggc aacttatcga gcagctttcg
    22861 ctgggcgtgt atgacgccgt gcgtcgcctg ctggggcgct tgcgcccgcg ccagctagac
    22921 gacttaacgc tggcgcaggc catccgttcg ctgctgcgcg aaatggagct ggaaagccgc
    22981 ggtattgtca gtcacctcga ctggcgaatt gacgaaacgg cgctaagtga aagtcagcgc
    23041 gtgacgctgt ttcgcgtctg tcaggaaggg ctgaataaca tcgtaaaaca tgccaatgcc
    23101 agcgcggtga cgctccaggg ctggcagcag gatgagcggc tgatgctggt gattgaggat
    23161 gacggcagcg gcctgccgcc gggctctcac cagcagggct tcggcctgac cggaatgcgc
    23221 gaacgcgtgt cggcgctcgg cgggacgcta accatctctt gtacccacgg tacgcgggtg
    23281 agcgtctcgt tgccccagcg ttacgtttaa ggaaggataa tgctttcgtt tttaaaagcc
    23341 ccggccaacg cgccgctcat caccgataag cacgaggttg acgcccgcta tcgctactgg
    23401 cggcggtata tcctgatcac catttggttg ggttacgcgc tgttctattt cacccgtaaa
    23461 agctttaacg ccgccgcgcc ggaaatcctt gccagcggta ttctgacccg cagcgatatc
    23521 ggcctgctgg cgacgctgtt ttacatcacc tacggggtgt cgaaatttgt ctccggcatc
    23581 gttagcgatc gctctaacgc tcgctatttt atgggcatcg ggctgattgc gaccggcgta
    23641 gtgaatattc tgttcggctt ctcgacctcg ctgtgggcct ttgcgctgct atgggcgctg
    23701 aacgcctttt tccaggggtt tggatcgccg gtttgcgccc gtttgctgac tgcctggtac
    23761 tcgcgtaccg agcgcggcgg ctggtgggcg ttatggaaca ccgcgcataa tgtcggcggg
    23821 gcgctgatcc ctctcgttat ggccgctgtc gccctgcatt atggctggcg cgtcgggatg
    23881 atggtggccg gattgcttgc catcggggtg ggcatggtcc tctgctggcg gctgcgcgac
    23941 cgtccgcagg cgattggttt accgccggta ggcgactggc ggcacgatgc gctggaggtc
    24001 gcccaacagc aagagggcgc gggactaagc cgcaaagaaa tcctcgctaa atatgtgctg
    24061 tcgaatccct atatctggct gctttcgttg tgttatgtct tagtgtacgt ggtgcgcgcg
    24121 gcgatcaacg actggggcaa cctgtatatg tccgagacgc tgggcgtgga tttggtcacg
    24181 gccaacacgg cagtatcgat gtttgagttg ggtggattta tcggcgcgct ggtggcgggt
    24241 tggggctcgg acaaactctt caacggcaac cgcggaccga tgaatttaat cttcgctgcc
    24301 gggattttgc tctctgtggg ttcgctgtgg ctgatgccgt tcgccagcta cgtcatgcag
    24361 gcggcctgtt tcttcaccac cggtttcttt gtcttcggcc cgcagatgct cattggcatg
    24421 gcggcggcgg agtgctcgca taaagaggcg gcgggcgcag ccaccggctt tgtcggcctg
    24481 ttcgcctatc tcggcgcgtc gctttccggc tggccgttag cgaaagtgct ggagatctgg
    24541 cactggaccg gtttttttgc ggtcatcgcc atcgcggcgg ggatctccgc gctattgctg
    24601 ctgccatttc tgaacgccca ggccccacgc gagacccacg aagcgtgata cacctcacct
    24661 ttttgcgctg aatggggcaa aactaagaaa ttttcccggt tttgcctgga cgctgtcgca
    24721 ggcccctttt cctgtggatt tttacaatgc ctgccattcg caggtataaa aattagctca
    24781 ggagtaatcc atgctggcct tcttaaacca ggtgcgcaag ccgaccctgg atctgccgct
    24841 caatgtgcgg cgtaaaatgt ggttcaagtc gttcatgcag tcctatctgg tggtttttat
    24901 cggctacctg accatgtacc tgatccgcaa aaactttaac atcgcgcaga acgacatgat
    24961 ctctacctac aggttgagca tgaccgagct ggggatgatt ggcctgggct tctcgatcac
    25021 ctacggcgtg gggaaaacgc tggtttccta ctacgctgac ggtaaaaata ccaagcagtt
    25081 tctaccgttt atgttgatcc tctccgctat ctgtatgctc ggcttcagcg ccagcatggg
    25141 cgcggggtca accagtctgt ttctgatgat cgctttctat gccctgagcg gtttcttcca
    25201 gagtaccggc ggatcgtgca gctactcgac catcaccaaa tggactccgc gtcgtaaacg
    25261 cggcaccttt ctcggcttct ggaatatctc ccacaacctc ggcggcgcgg gcgcggcagg
    25321 cgtggcgctg ttcggcgcca actacctgtt cgacggtcac gtcatcggca tgtttatctt
    25381 cccgtcgatt atcgcgctga ttgttggctt tatcggtctg cgtttcggca gcgactcccc
    25441 ggaatcttac ggtctgggta aagctgaaga actgttcggc gaagagatca gcgaagagga
    25501 taaagagact gaagaaaacg aaatgaccaa gtggcagatc tttgttgaat atgtgttgaa
    25561 aaacaaagtg atctggctgc tgtgtttctc caatatcttc ctgtatgtgg tgcgtattgg
    25621 tatcgaccag tggtcaaccg tctacgcctt ccaggaactg aaactttcta aagaggtggc
    25681 gattcagggc tttaccttgt ttgaagtggg cgcgctggtc ggcacgttgc tgtggggctg
    25741 gctctctgac ctggcgaacg gtcgtcgcgc gctggtagcc tgtgtggcgc tggcgttgat
    25801 catcgctacc ctcggcgtct accagcacgc cagcaaccag tatgtctatc tggcctcgct
    25861 gttcgcgctc ggtttcctgg tgtttgggcc gcagctatta attggtgtgg cggctgtcgg
    25921 tttcgtaccg aaaaaagcca tcggcgctgc ggacggtatc aagggcacct tcgattatct
    25981 tatcggcgat agctttgcta agctgggtct gggcatgatt gccgacggca cccccgtttt
    26041 tggtctgacc ggttgggcgg gtaccttcgc cgcgctggac gctgccgcga tcggctgtat
    26101 ctgcctgatg gcgatggtcg ccgtgatgga agagcgcaaa atccgccgtg agaaaaaaat
    26161 tcagcaagtc aatatcgctt aaatgtgtgc atttggtaac gttttgcccg gcttaacgcc
    26221 gggctttttt atgccttgcg ttcgtcagac aggacatccg gtgtctggcg taaatgaaga
    26281 caggcgttaa taaatcacat cctgacaggc cagaacgtcg acagttataa atttaccgtt
    26341 atgatgggca tcctgtttgg tgacggatgt gcgcatgatt tggttgattc tggccacgtt
    26401 tgtggtggtg tttattgtgg gttttcgggt gctgacatcg gatacccgcc gggcgattcg
    26461 ccgtctgagc gaacgtctga atattgatgt agtgccgata gaatcgatga ttgatcagat
    26521 gggtaaaacg gcgggcggtg agtttttaca gtatctgcat cgccctgatg aatcgcattt
    26581 gcaaaatgcc gctcaggtgt tactgatctg gcaaatggtg attgtcgatg gcggcgatca
    26641 gaatttgcag cggtggcatc gcttgctgca aaaagcgcgt ttagccgcgc cgatcaccga
    26701 cacacaggta cggctggcgc tgggcttttt gcgcgaaatg gaacccgata tgcaggagat
    26761 caacgcgttt caactgcgct ataacgcctt ttttcagccg gaagagggtg tccactggct
    26821 gcattgatac tcttcactat ctcgttaaca aaagacgaga tgaatgaggc tggcaagggc
    26881 ggcgagccac gattaacggc cggatggcac gattcatcgt tagccaaata aagcgtagcc
    26941 gccatcgtat ttgctaaggg tgaaccacag aagtaacgca ccgaataacc gctaacgacg
    27001 ccaaaacatc agagacttat agctcatcat ttctgtgaca tatatcacgg aaatgtgatc
    27061 ttgttttgaa caccaaaact gtgactcctt gccatacctc ctgtctcaaa atttcttatc
    27121 ataaactcga agttgtacat gattgtctat agacaactct aaatgtttag gcgcgcacta
    27181 tgaaaacatt gagtaaaagt tcacacatcc cactgtatca acaggttgtg gagtggataa
    27241 gggaaagtat ttatagcgga gaattggttg aggatgaccg gataccttca gagtttcaaa
    27301 tcatggatat gctggaggtg agtcgcggta ccgttaaaaa agcggttgac caacttgtcc
    27361 gggaaggtgt tcttgtgcaa gtgcagggta aaggaacttt cgtaaagaag gaaaatgttg
    27421 cttacccact gggtgaaggt ttgctctcct ttgctgaagc cttagccagc cagaagataa
    27481 acttcacaac cagcgtcata acctcccgac tggaacccgc taaccgcttt gtagcagaga
    27541 aactgagtat caaaccggga caagatgttt tatttcttaa acgccttcgt tgtattggcg
    27601 atgaaaaagt catgttgatt gaaaatcgta tcaacattga tctctgcccc ggtattattg
    27661 atgtagattt taccagggag aatttatttt cagcaataga aagattatct gataagaaaa
    27721 taagtttttc tgaaagccgt tacgcagcta aattaattgg taatgagcga ggccattatc
    27781 ttgatattgg tgaagacgca cctgttttgc atttggaaca gttggtattt ttctctagag
    27841 gattggccat tgattttggt aacgtctggt taaaaggtaa taaatattat cttggcacta
    27901 ttttacagcg cctggatgcc tgactagcaa agaggaatct atgcaggata ttcattttcg
    27961 ccgtcattat gttcgccacc tccctaaaga ggtgagtcag aatgacataa tcaaggctct
    28021 tgccagtccg ttaattaacg atggtatggt tgtatctgat tttgccgatc acgtcattac
    28081 gcgagaacag aattttccaa cgggtctacc ggttgagcct gtaggtgtcg ctattccaca
    28141 tactgatcac aggtatgttc gccaaaacgc cattagcgtt ggaatactgg cagaacccgt
    28201 caatttcgaa gatatgggcg gggaaccaga tcccgtacct gtcagggtgg tgtttatgct
    28261 tgctttaggt gaaagcaata agcagctcaa cgtactgggt tggattatgg atgtgatcta
    28321 ggatgaggat tttatgcagc agttactggt catgaatgat gatgaaattt atcagtcaat
    28381 ttacacacgc atatctgaaa gaggtgaagt atgagtaaaa tgatactatt tgtttgcgca
    28441 acgggtgttg ctacttccac ggctgtggca gaaaaagtaa tggaatattg taaagacaat
    28501 gggcttgatg ttaattattc ccaaactaat gtagcctcat tgccaaacaa taccgatggt
    28561 gcagctttgg ttgtatcaac aacgaaagtt ccttatgaac tggatattcc ggttgttagt
    28621 ggtctgccaa tcattaccgg agtaggtgaa gataaagttc ttgaaaaaat agtttcaatc
    28681 cttaaaggcc aagcctgatt tcataaataa aaaacagata aattacccag gcgctaacgc
    28741 gaggtctggt cacatctgaa taagaggtcg gatatgaatg atatagcaca tactctctat
    28801 accgttgtgc aatatgtcct gggatttggc ccaacggttt tattgccgct ggtccttttt
    28861 ttcctggcat tgttcttcaa agtaaaaccc gctaaagcac ttcgctcatc gttaattgtc
    28921 ggaatagggt ttgtcggaat ttatgccatc tttgacatac ttaccagcaa cgtaggcccg
    28981 gctgcacagg caatggttga gcgaactggt attagtcttc ctgttgtcga tttaggctgg
    29041 ccaccattgg ccgcaattac ctggggctca ccaatcgccc cctttgtcat tccgctgacg
    29101 atgctgatta atgtcgccat gctggccctg aataagacac gtactgttga tgtcgacatg
    29161 tggaactact ggcactttgc cctggcggga acgctggttt actacagcac agggagtttt
    29221 gttttgggtc tgtccgcagc cgctattgcc gcgatcgtgg ttctcaaact ggcggactgg
    29281 tcagcgccat tagtggcaaa gtacttcggt ctggaaggta tttcacttcc gaccctgtca
    29341 tctgtcgtct tctttccaat tggattgctg ttcgacaaaa ttatcgacaa gatcccgggt
    29401 gttaaccgta ttcatattga tccggaaaac gttcagaaaa aaatgggaat cttcggcgag
    29461 cctatgatgg tgggtactat tctgggggtc ttgttgggca tcattgccgg gtatgacttt
    29521 aaacatatcc tgttgctggg gatcagcatt ggcggtgtca tgttcattct tccgcgtatg
    29581 gtacgaattt tgatggaagg tttattacct ctgtctgaag ccattaagaa atatttgaat
    29641 gccaaatatc ctggccgtga tgatctcttt atcggactgg atatcgcggt agcagtaggt
    29701 aacccagcca ttatctctac agcactgatt ctgacaccca tctctgtctt cattgcattc
    29761 cttcttcctg gcaataaagt cctgccactc ggagaccttg cgaacctggc agtcatggct
    29821 tccatgattg tactggcatg tcgtggcaat attttccggg ctgtgataac cgcaattcct
    29881 gttattatcg ccgacttgtg gattgcgacc aaaattgcgc catttattac cggtatggct
    29941 aaagatgtca atttcaaaat ggctgagggg tcaagtggtc aggtatcaag cttccttgat
    30001 ggcggtaacc ccttccgttt ctggctgctt gaaattttca acggaaatat tattgctatc
    30061 gggctgattc ctgtgcttgc gctggttatt tatggtgttt ttcgcctgac aaaaggaacg
    30121 gtctatgcct gattaccacg cagcgcttgt cattgacatt ggtacaacta actgcaaagt
    30181 cagctgctat tcctgtcatg acgtgtcagt tctggaagtc cgcaagtttc cgacgccaac
    30241 aatatcgtcg gacaaaggcg aggtagattt agatatcgaa gcgctgtggc aggcactgcg
    30301 actggtaatg gctgaactgg tggcttcagt accgtttccg gtaaaaaata tcagtattgc
    30361 gagtttcggt gagtctggcg tctttgtgga taaggagggc gtcattctta ccccgatgct
    30421 ggcctggtat gatcgacgtg gtgaatctta tctctcgtca ttaagcaagg cagaggctga
    30481 agaactgtat tctataacgg gattgccacc tcacagtaat tactcagcat ttaaaatgag
    30541 atggttgctt gataactact ccttgcatga aagaaaagat atctgctggt tacatgctcc
    30601 agaagtgttg ttgtggcgaa tgacaggtgc gaaaaagacg gaaatatccc tggccagtag
    30661 aacgttgtgt ctggacattg ctcgccgtac ctggtctcgt aatgctgccg ggattctcgg
    30721 cataccgttc ggtgtactgg ctccgttgat aaagccgggt gaagtggctg gatgggtgac
    30781 ggcaacgctc aggcaggagt tgggattacc acatgaggta aaagttaccc tggccggaca
    30841 cgatcatatg gtcggtgccc gcgcattaca gatgcaaccg ggcgatgtgc tgaattctac
    30901 cggcacgaca gagggtattt tactgctgaa tacacagcca acgcttgatg tgcaggctcg
    30961 cagggataag ctggcaaatg gttgttactc cgatggtgaa tttttcacgc ttttcgcttc
    31021 tctgcctgtc ggcggttatg cgcttgaatg ggtgaaaaaa acctttcgtt taactgataa
    31081 ggaaataagc acaggcctgg aaaaagtcat ggagcaatac ctcaaacctt cctggtctgt
    31141 cgagcatgtg ccggtattta ttcctcattt gcggggctcg ggttcgccac ataaaaacca
    31201 gcacactcgt ggcctgcttt ttggtctgac ggattcactt cctccggagt ctctgcttga
    31261 gagtgtcttt atcggcctgg cgatggagtt tgcacactgt cacgggtgct ttaatatccc
    31321 ggcaggcagg acagtaaaag tcattggccc tgcggtgaaa aacccatact ggctccagtt
    31381 gaaggctgac atcctccagt gtccaattga ggccattgct tttgatgaaa ccgtctccct
    31441 tggagcattg ttgatagcct gtccgaatgt tgtccccccg actgttcctg tggctgagcg
    31501 atattttcct gacgcggttc gttctgcaaa gttgaaaata tatcagcagc aatggctgtc
    31561 attttaccaa tttaaactgc ggcaagaagg ggcgtttatt ggtgaataac tgtgataact
    31621 caatagttcg ataatttact tatactgctc acataaatat ctggagttaa tatgtcttta
    31681 gtcaatggta ggatcctgct caattgtatt caggaaaaac atgtccttgc gggggcattt
    31741 aatacaacga acctggagac aacaatttcc attcttaatg caatagaacg ttccggattg
    31801 cccaatttta ttcaaattgc tcctactaat gcacagcttt caggttacga ttacatttat
    31861 gaaatagtga agtgacatgc cgataaaatg gatattcctg tcagcctgca tctggatcat
    31921 gggaaaactc tggaagatgt taagcaggct gtccgggccg gatttacctc agtaatgatt
    31981 gatggcgcgg cgctaccgtt cgaagaaaat attgcattta cccgagaagc tgtcgatttc
    32041 tgtaaatcat ttggtgttcc cgtcgaagcg gaattaggcg ctattctggg taaggaagat
    32101 gatcatgtca gcgaggctga ctgcaaaact gaacctgaga aggttcagcg ctttgttgag
    32161 gagacagggt gcgacatgct ggcagtgtca attggtaatg tacatggtct tgaagacatc
    32221 ccacgcattg atatcccgct attacaacgc atcgcgtctg tcagtccggt acctttggtt
    32281 attcatggag gttctggtat tgacgcggat attcttcgca gctttgttaa ttacaaagta
    32341 gccaaagtga atattgcgag tgatttgcgc aaagccttta ttactactgt tggtaaggct
    32401 tgggtaaata ataacaacga ggctaatctg gcgcgtgtca tggcgagcgc aaaacaggca
    32461 gttgaggatg atgtttattc taaaattaag atgatgaata aacatcactc agcactccgc
    32521 aaagtctctt aaggaaaata tatgattaga caaaaagtac gcgttatgaa cagtacgggg
    32581 cttcatgcgc ggccagccgc tacacttgcg aaaattgtca aaaaatacca gtcttcatta
    32641 acgctagtta ataatgacaa agaaattccc attaaaggaa tgatgagtat tttgggggct
    32701 ggcgtaaagg gaaacacaat gattgattta atttgtgatg gacaggatga actggctttt
    32761 atggatgaat taaaatccgc atttgctgat ggctttggtg agtcagtata gtgcaattcc
    32821 cgtcaaacgg cgcaggaagt tgtagaggct tcctgcactc attatcgtat gaatagcctt
    32881 aacagaccat cggtaaaacc ctcataccag cacctttagc ccgtgttttt ggacaacatt
    32941 aagtagtttc agtgacatcc cgctgggacg cttggcgccg ctttcccact tttgaaccgt
    33001 tgatacgctg gtattcaggt accgagcgaa aaccgactgg ctaacgttga gttcttctcg
    33061 taacgctttt atttcaagtg gctgcaggtc tttgatgctg cttaagcagg ccgtgtcaaa
    33121 actgcgcatt gtctcctggg gaatggcatc cacgctaaat aatccagatg ccgcgctatg
    33181 aatcgcttca aaggcagggc ttttgaattt agtttttgct gacatggcgc acctctacca
    33241 gttctttgtt attaatgagt gccgttatct gatcttcggt caggcaagca tagtgttttg
    33301 ctaactcacg gaaacccgca agttcgcgat agcgaatgtt ggccatattc tgtttggtat
    33361 acaggaaggt gtaaaaccaa tgttcgcctc cctttgccaa cacgattgcg cgatcgcggt
    33421 tttaattgag acgtttttat aaactccgcc gccaagatta tctgcttttc cttgcagtac
    33481 ggcgttgatg gcctcgctta actcgtcatc ttttatcgtg tgggacttcg cttctctgtt
    33541 aaaccacctg gttttgaaga ttcgcatcag gttgacatcc tgtaatctaa agtatagcac
    33601 caggtgatac actatgtctt accttttggt tttacacgca gcgagagaag ataattctca
    33661 acgctcgacc agcctcgcaa aatgcagcgc aacaatgtca gttgctaaaa cgttaatcag
    33721 atcacatttt gtaatgttac actgcgtgga ttttccgcac taaaacgacg caggtaacca
    33781 caatgaatga aaatatcgca gaaaaattcc gcgctgatgg ggttgccagg cctaactggt
    33841 cagccgtttt tgccgtggcg ttttgtgtcg cctgcctgat taccgttgag tttttgcccg
    33901 ttagtctgtt gacgccgatg gcgcaggatc tggggatctc cgagggcgtc gccggtcagt
    33961 cggtcaccgt tacggcgttt gtcgcgatgt tttccagcct gttcattacc cagattattc
    34021 aggcgaccga caggcgttat atcgttattc tgttcgccgt tttgctgacg gcttcttgtc
    34081 tgatggtctc ctttgccaac agctttacgc tgctattgct gggccgcgcc tgtcttgggt
    34141 tggcgctggg cggattctgg gcgatgtcgg cgtcgctgac catgcgactg gttcccgcgc
    34201 gtaccgtgcc gaaagcgctg tcggtgattt ttggcgcggt ctccatcgcg ttagtgatcg
    34261 ccgcgccgct gggcagtttt ttgggcggta ttattggctg gcgtaatgtc tttaacgccg
    34321 ctgcggtgat gggcgtactg tgcgtcatct gggtggtgaa atcactgccg tcgctgccgg
    34381 gcgaaccttc tcaccagaaa cagaatatgt ttagcctgtt gcaacgccct ggcgtgatgg
    34441 ccgggatgat cgccatcttt atgtcttttg ccgggcagtt cgctttcttt acctatattc
    34501 gcccggtcta tatgaatctg gcgggctttg acgttgatgg tctgacgctg gtgctgctaa
    34561 gttttggtat tgccagcttc gttggcactt ctttctcctc ttacgtcctg aaacgttcgg
    34621 taaaactggc gctggccggt gcgccgctgc tactggcgct gagcgcgctg acgctcattg
    34681 tgtggggaag cgacaaaacc gtggcggcgg caatagcgat tatctgggga ctggcgtttg
    34741 cgttggtgcc ggtgggatgg tcaacgtgga tcactcgttc tcttgccgat caggcggaaa
    34801 aagccggttc catccaggtc gcggtgattc aactggcaaa tacctgtggc gcggcggtgg
    34861 gcggttatgc gctcgacaat ttcgggctgc tttcgccgct ggcgctttcc ggcggtctga
    34921 tgctgttgac ggcgttagtc gtggcggcga aagtccgtat tacgccaatg agttgatatt
    34981 gctgccattt gtaggccgga tacgacgtta gtcgttatcc ggcaataata aacgcttaat
    35041 caaaaccgtt atgctctgcg gtggcggcaa accattctcc gctttttttc accgtgcgcg
    35101 tttgggtggc taaatccagt tgtacaaaac catagcgatt tttatagccg ttcagccatg
    35161 accagttatc gataaaggtc cacatgtggt agccaagaca gtgacagccc tcgctaatgc
    35221 ctttatgcag ccatttaaga tgctcagaga taaagtcaat ccggtaatca tcgtgaatct
    35281 gtcccgcttg cacaaaacgc tgctcgttct caacgcccat cccgttttcg gagataaaac
    35341 agcgcggatt gccgtaatta tcccgcaggt tggtgatgat gtcgtaaatt cctggcgcgt
    35401 aaatttccca gccgcggtaa gggttcatct tgcgccccgg catgtcgtaa tagtcaaata
    35461 accactccgg cataaacggc gcttgcggat tcaccgctgt atcacggcat ttcacgcggc
    35521 gcggctgata atagttaatc cccagtaaat cgattttgcc gtcggcaata agctgacggt
    35581 cgcctggctg acaggcaggc agctggtcat aggttttcag cagcgccacc agctccgccg
    35641 ggtattctcc ctttaatacc gggtcaagaa aactgcggtt gaataacaga tccgcatgat
    35701 gcgcggcttg cacatcggcg ggatgctgcg agcgtgggta ggacggcgtc agattcagca
    35761 ctacgccgat ttcaccgtcg tagcgcccgg cgcgccaggc gcgcacggcg gtcgagtgcg
    35821 ccagcacggt atggtacgcc acggtggccg cacgtttaaa atccaccaca ttgggatagt
    35881 ggaagtcgta caaatagccg ccttccaccg gcacaatcgg ctcgttaaag gtaaaccagt
    35941 gcttcacgcg gtcgccaaac aaggtaaaac acgtttgcgc gtaccgacca aacgcctcta
    36001 cgacgtcgcg attttcccag ccgcctttct cctgcatgac catcggcata tcaaaatgga
    36061 acagcgtaat aaacggcgtg atgccctgcg ccagtagctc gtcgatgacg tgattgtaga
    36121 agctcaccgc ttgtggattc acctcgccta caccgtctgg aatgagccgc gcccagctta
    36181 gcgaggtgcg aaaactgttg tgttttaact gtttcagtag cgcgatgtct tgcttccagt
    36241 ggcgatagaa cgttgaggtt tccgctggac cgatgccctg atgaaaacga tcaggctggc
    36301 gctcgaacca cacatcccac gtggtctggc ttttaccacc attcagacta tccccttcgg
    36361 tttgcaacgc tgagcaggcg ctgccccacc agaagttatc gggaaaacgg tatcgcattg
    36421 tcgtactcct tgatcgcgta aattcgctcc agaatatgcg cttttggcga acagaaaccg
    36481 gttacagtcc gcattttcgc gaccaaaaag cggaaaagct gtgctacatc tccgggcatt
    36541 ccaccttgcc gagagcctgc cagtagttat gctgattgtt gcgctctatc gcgatcatcg
    36601 cctcccgaat atgctgctgg ttcccctcgc ttgccatgat ttttttctcc caggcttcat
    36661 cggttagcgc gcctttgggc gtacacattt tgcgcaaatc ctttaaaatc gtattttttt
    36721 catgcgccga ctggagtgag ctaaacggag agtcggcata cgtgacgccc ggtagcgcga
    36781 caagtgtggc aataagcaga agcgtttttc gtttcataaa cggtatcctt atcggtttgc
    36841 actttttcaa gagtaagtgt agaccgtgcg acgttcactc atcggggcgt gctatccgtt
    36901 ggcgttgaag tcaggcaaaa gtgggaaggc ggtttctcgc tgcgccttca ctttcttgcg
    36961 tggcagaata gtgtatgttc tgactactct tttatttcgt aagcggtagt gtaatgagac
    37021 gtattgagat cgtactggga gagctggaac ggctgacgcg cgggctatgc cttgccgatt
    37081 tggcgcagga gacggcgttt acggcggagg cgataggttt caatcttggg ctggcgcgta
    37141 actccgtcag caaagatctc aatcagttat ggaatgacgg cctggcaatc aaaagccgtg
    37201 gccgcccggt ctattttttg gcatcgccag gcgctggaaa cgttgctggg acgtcagctg
    37261 gaagagtctg aacgcgaggt gcggtcggtg gcggatgtgc tgccgcatga agagcattac
    37321 gcgcccgacg atccgtttac cagcctgatt ggttacgatc gcagcctgcg cgatgcggta
    37381 gaaaaaggcc gtgcggcggt gctctatccg cacggtttac acgttctgct taccgggccg
    37441 tccggcgtcg gtaaaacctt ttttgcggaa ctgatgcacc gtttcgcctg tgaacaggcg
    37501 agcggcgcta tcccgccgct ggtctacttt aactgcgcgg aatacgccca taacccggaa
    37561 ctgctctcct cgcatctgtt tggtcatcgg cagggggcgt ttaccggcgc gaatgaacat
    37621 aaaacaggcc tcgtggagca ggcggacggt ggttatctgt tgctggacga ggtgcaccgt
    37681 ctgtcttatg aagggcagga aaagctgttt tctattctgg ataaaggcga gtaccgtccg
    37741 ctcggcgtga gcagccagcc gcgatcaatt tcggtacgcc tgatttgcgc cactaccgaa
    37801 ccggtcgggt cggcgctgtt acgtactttc cagcggcgta ttcaggtatg cattgatttg
    37861 ccgggcattc gccagcgctc cgttgaagaa cagatcgaac tgatcgtggg gttcttacag
    37921 cgggaaagcc gcaaaataga acgcacggtc agcattgata aaccgttgtt gctctggttg
    37981 ctgaataaac ccctggaagg caatatcggt cagctaaaaa gcgatattca gtttctttgc
    38041 gctcaggcgt gggcatcggg aatgaccgag cataacgaca cgctacagct ggataaacgg
    38101 ctggcggaga tgtcggttaa cccgacgccg gaacagcgtc tattggtgga tactctgttt
    38161 gacggtaaag cgcggctaaa tatagacgcg cgcacgctgc ccgcattgaa gacgtcgctg
    38221 gcgaccgggg cggaaattga agagagcgac ctcttttaca gcttcctgac gcgcgagtat
    38281 gttaatttgc gcaacagtaa cgtccccccg gcggagacgc tggcgatcct gaaaaataaa
    38341 ctcagctcga tttttgaata cggtctctat agccgcgaca gcgtggcgca tccgccgcgc
    38401 tatggcgacc agattgaaga gcgcgtgacg ctgctgattg gctgcgtaga gcaggtgttg
    38461 ggcttttcgc tgccggaaaa tctggttaac ccactgcgta aacacttcct ggcgctgata
    38521 ggctacgtgc agcgcggcct gatcccgcag ctttactctt ccagtttgat cctggatcgc
    38581 tgcaaagacg aatatgacaa cgccacgctg ctgtgtcgga aaatcaacga actgctgcat
    38641 atacagtgtc cggcgacgga agtggtctgg ctatgcctgt tcctgaaaga gtgccgccat
    38701 tatcgtcagc gtatcgatgc cagccccgac tgcggggtca ttttgatcgc tcacggcgcg
    38761 accaccgcca ccagtcaggc gcaatatgtc aaccgcgtgc tggagcgcga gctgttcagc
    38821 gccatcgaca tgccgtttga acagtcggtg catgacacgc tggaaacgct gacccaaatg
    38881 attcaaaccc gccaatatcg gcggcttatc ctgttggtgg gcatcggttc attgatccat
    38941 ttcggcagca ccatcagtaa attattccag atagatgttt tgctcatgcc gaatatcacg
    39001 ctgaccagtc tactggaagt cgggctggat ttaagctatg aaaccagcga cttaccacag
    39061 ttgacggcgc tcctgcagag taaaaatatc ccctgccagc tttgtacgcc gcagcaggag
    39121 aacggcggca aagtgctggt catctcctgt attaccggca tgggaacggc ggaaaaaatc
    39181 aaaaaggtgc tggaggagag ctttggcgaa ctgatgtcgc aggacaccag gatggtgatc
    39241 cttgattata acgaggtacg aagtctggag cgcgttcagc aggcattgaa tgccagcgag
    39301 cggctggcgg ggattgtcgg cactttccag ccggggctgc cggatattcc gtttatttcg
    39361 ctggaagagc ttttctccga acaagggccg gaactggtgt tgagcctgtt aacgcccgat
    39421 ctgtccaacg ctgaacgccg tctggagatg gagcgcagcg cgatgcgctt tatcagcgcg
    39481 ctaacgatgg agagcatcat caaccatatt tctgtgctta acccgcagcg tattctgaaa
    39541 gagatggagg gcgtttttaa ccatctgacg tcttcgcttt ccctgaaacc aagccgccag
    39601 gtgacactgc gcttcctgat ccactgctgc tgtatggtag agcgtattgt gattaaccga
    39661 aaaccgttac agatggcgct ggaacgtcag ccgaatctgg acgcgcgcgc gtttagtgtc
    39721 atcaaatccg cttttctgcc gatcgaagac gcgtacgcca tccgtttatc ggatgcggaa
    39781 tatttttata tctacgaact gctctatagc taatcctttt actggcgggg cttcgcgcct
    39841 cgccagacct ttcttcttcc tcgcgtgaca caaattctgg cacaaccttt gctcttctga
    39901 tgatgcgtta tgccggatag cggcgtaaac gccttatccg gcctaccggg agtgtcctgt
    39961 cggtccggta agcgcagtgc caccgggcaa tatatgccgg tgttctcatg taattgcgcc
    40021 aggaggccat tattttgact accacacaac cgttgcccca catcctgctg ctgacgcatg
    40081 gcggctgggg acaaccgctt tgcaacagcc tgcgtatggt cacgggcgaa attaaaggcg
    40141 tgacggaaat cgcgctaatg cctgtcgata cgctgggcga gttttatcaa cgcgtcgagg
    40201 ccgtggtgaa aacgctgccg gaaggctcgc tgatcctgac ggattttgtc ggcggcacga
    40261 cgtccaacgt cgcggcgcgg ctaagcgccg attatccggt ggcggtgatt gccggattga
    40321 atgcgtcgct actgctggag gcgctggaca ggcgcgaaca agggatgcta accgcctgcg
    40381 tggatgagtt agttgaggcc gggcgcagta gctgcctgga tgtggtcgcc catgtacgtc
    40441 agctacaaca atcactctaa ggaaaacatc atggccaata tcgttttatg ccgcatcgac
    40501 agccgtctca ttcatggaca ggttgtcacg aagtgggtcg gacaatctca ggcgaaccgg
    40561 atagccgttg tgagtgatga actggacgcc gatccgttta tgaaaaatat ctacctgatg
    40621 gcggcgccgc caaatatcaa agtggattgc ttcggcaacc agagttttgc cgctgcatgg
    40681 aaagaaaatc agcttggcga cggtaacgtg ctggtgcttt ttccctcact ggcggcggtg
    40741 caggacgcca tacaattggg ctttgacgtc acccgcattc aggttggcgg tctcggcggc
    40801 gggccaaacc gcaaggcggt ttttcagaat attacgctgg atgaaaaaga cgtcggcatt
    40861 cttaacgacc tgaaaaaccg tggcgttcag gtatttttcc agaccattcc ggaagataag
    40921 ccgcagccgc tcgacgatat cctgaaaaaa ttctaaccct ttaatagaca caaaatcatt
    40981 ctggatgcat cgaggcggca actgagtgaa tcccctggag cttactaaag taagtgactg
    41041 gggtgagcga aggcagccaa caaagaggca gcctgaagga tgaagtgtat aggataacac
    41101 tatggatacc ttactctttg caagcctgat ggggttgtat tactggtttg cccgtttacg
    41161 cctcggctac accttctccg cgatgctgtt acaaccggtg gtgatcgcgg tatttgtcgg
    41221 gcttttgctt ggcaatatgc agaccgcgat gatcatcggc gcagggatgc agctcgttta
    41281 tttgggcgtg acctcaacgc cgggcggcaa cgtgccgtcg gacccggcgc tggcggcctg
    41341 tatctccatt cctatcgcgg tgaaggccgg tatggaccca aacctggcga tcgcgctggc
    41401 aatcccgttt ggcgtgattg gcgtgtttct cgatcagctg aggcgcacgc tgaacgccgc
    41461 ctgggtgcat atggcggata aacacgcgga aacggcaaac atggcgggca tcatgcgttg
    41521 cgcctttctt tacccggcat tgctggggct ggtgctgcgc ttcccggtgg tctttgccgc
    41581 taactacttt ggccaggatg tggtggaaag tttccttaaa ctgatgccgc actggttaac
    41641 ccactccttt gaaatcatgg gcggcattct gccggcgctg ggctttgcca tcaccattat
    41701 ggtgatcggt aaaaagagcc tgttgccgtg gtttatcggc gggttcttcg cggtgttata
    41761 cctcaaggtc gacatcatgg cgatggccat cttcggcacc tgtgtcgcct tcttgattaa
    41821 aggcctggcg aaaaatgaag gagcagcatg atgagcagtg acgtaatgca acatgaactg
    41881 gttgagcgcg cgcgggaaag cggggcgctg accaaagcag atatcaccaa agcctggttt
    41941 atctactggc tgggcgccga ggtttccagc tcctatgagc gcttacaaag cctgattttc
    42001 tgcgcctcga tgacgccgat catcaaaaaa ctttacccac aaaaagagga gcaggtagaa
    42061 gcgctaaaac gccaccttaa cttctttaac tccgagcaga ccttcggcgc ggtgattcag
    42121 ggcatctcta ttgccatgga agaacaaaaa acgcgcggcg agccgattaa cgactcgtct
    42181 atcaccggca ttaaaacggg cctgatgggg ccgcttgccg ggatgggcga ctcgattatc
    42241 tgggcggcgg tgatgccgct gttgatagcg atctttattc cgttcgcggc aaatggcagc
    42301 gcgatgggcg gtattatccc gctgattctc tacccggcga tcaccctggc gatcagctac
    42361 ggtatggtcc acaagggata tacactgggg cgtgattcga ttatcggcct gctgcaaggg
    42421 gggcgaatca aagaactgat ctacggggcc aacgtgctgg gtttgatcat gatgggcgcg
    42481 ctttccgcca gctacgtcaa aatcaccacg ccgttaaaaa ttagcgcctt gaaaggatct
    42541 gaagtggtgg ttcagcagat cctcgactct atcgcgccgg gcttactgcc actggcggcg
    42601 gtattcgcca tctacttcta tctggtaaaa aaagggccgc gctacaccac cattttgctg
    42661 tcgattgtcg cactgagcat agtctgttcg ttgttgggag tgctgtaaat catgacgccg
    42721 aatatctatc aacaactggg gttgaaaaag gtcattaacg cctgcggcaa aatgaccatt
    42781 ctgggcgtct caagcgtcgc gccggaggtc atgcaggcca ccgcgcgcgc ggcttccgct
    42841 ttcgtcgaga ttgatgcgct ggtggaaaaa accggcgaac tggtatctcg ctatacgggt
    42901 gctgaagata gctatatcac ctcgtgcgcc tcggcgggta ttgccattgc cgtcgctgcc
    42961 gctatcaccc acggcgatcg ggcgcgcgtc gccctgatgc cggacagtac cggtatggcc
    43021 aatgaggtag tgatgctgcg cgggcataat gtggactacg gcgcgccagt caccagcgcc
    43081 attcgtcttg gcggcgggcg catagtggaa gtggggtcga gcaatctggc ggcccgctgg
    43141 caactggaaa gcgccattaa cgaaaagacc gccgcgctac tgtatgtgaa atcacaccat
    43201 tgcgtacaga aaggcatgtt gagcattgac gattttgtac aggtggcgca ggccaaccac
    43261 ctgccgttga ttgtcgatgc cgcggcggaa gaggatttgc gcggctgggt ggtgagcggc
    43321 gcggatatgg ttatctacag cggcgcgaaa gcctttaatg cgccaacctc cgggtttatc
    43381 actggtaaga aaacgtggat tgccgcctgc aaagcgcagc accaggggat tgccagggca
    43441 atgaaaatcg gcaaggaaaa catggttggg ctggtgtatg cgctggagaa ttaccaccag
    43501 ggccagacga ccgtgaccgc agcacagtta cagccggtcg cggaagcgat ttctgccatc
    43561 catgggcttt atgccgatat cgaacaggat gaggccgggc gtgcaatctg gcgtattcgt
    43621 gtgcgggtga acgcatcaga attggggctg aacgcgcagg acgtcgaagc gcagttgcgc
    43681 ggcggcgaga tagcgattta cgcccgcaaa tatcagcttc atcagggggt ttttagcctc
    43741 gatccacgca cggtagctga aggggaaatg gcattgattg tggcgcgact cagggagatt
    43801 gcagaacatg cagcagatta atttttatcg tcagcgggta gcgattaacg tgctggcaaa
    43861 ggatatcgcc aacgcgaagg ctatctatga agccgccgaa ggccatgcgg tcattggtgt
    43921 actttccgcg cagttcgcta cggtagaaga gggcgtgccg gaggtgaaac gctggatggc
    43981 ggaggtgccg tctatctcgg tggggctggg cgcaggcgac ccggcgcagt actacaaagc
    44041 ggcgatgatt gccgcccata ctcacccggc ccatgtcaac cagaccttta ccggcagcgg
    44101 cttcgcagcg ggcgcactgg cggcgacagg cggtgagcaa acacatatta acgccctggt
    44161 cagcccgacg ggaacgcctg gcgaggtggt gatttctacc ggcgtcagca gcagccaggg
    44221 aatgccagcc cgcgtttcct gtgaagcggc ggtacgcatg atgcaggata tgggcgcaca
    44281 tgcggcgaag tttttcccga tgggcggcga aaagtcgtta ccggaactct atgcgctggc
    44341 gacaaccgcc gcccgccacg gcatgacgct catcgagccg accggcggta tctcactgga
    44401 taatttcggt attatcctgc aaacctgcct ggaggcaggc gtgccgcgcg tcatgccgca
    44461 tgtttacagc tcgattatcg atccgcaaac cggcaatacg cgccccgaag acatcattca
    44521 gttgatggag atagtcaaag cgctggtgtg agatttatcg ccgaagagcg ctacgtttac
    44581 ctggcctaca gatgacgtgt atttgtaggc ccggttagcg ttacgctacc gggcgataat
    44641 gcgtagcagg ctgagcaaaa atgtacgtat tgcagccgtc agtgattccc tttcgagcct
    44701 cctcgcaggg ttaaattttc ctgaatgctg tctgtatttt tggcgagtac agtggcgtca
    44761 tcttattcct caggtgacgg atcgccatga aaaaaagccc cacgtccacg cctcatgatg
    44821 cggtattcaa aacgttttta cgccatccgg ataccgcgcg ggattttctc aatattcatc
    44881 ttccccattt gctaagaata cgttgcgatc tgacgacgtt gaaactggcg ccggacagtt
    44941 ttatcgagaa aaatttacgc gcgttttatt ccgacgtcct ttggtcgcta aaaacgtgtg
    45001 aaggtgacgg ttatatctat gtcgttatcg agcatcagag tacgccggac gcgcatatgg
    45061 cgttccggtt aatgtgttac gcgactgccg cgatgcagcg ccatctggat gctggccata
    45121 aaacgttacc gctggtgatt cccatgctgt tttaccatgg cgcgaaaagc ccgtatccct
    45181 tttcgctttg ctggctggat gagtttggcg atcctgcact ggcgcgtcag ctttatgcga
    45241 cggcatttcc actggtagac attacggtgg tgccggataa cgagattatg cagcatcgac
    45301 gtatcgcgat gctggaactg gtacaaaagc atatacgtca gcgcgacctg atgggattgg
    45361 tcgagcgttt agcggtactt ctgattacgg gaaacgctaa tgacagtcag ctaaaagcgc
    45421 tgtttaatta tttgctaata cagcatggca gcacgcctcg ttttggcaag tttatccgcg
    45481 aggtggcgcg ttgtgttccc caacacaagg agagattaat gacgatcgta gacagaatac
    45541 gtgaatcggg gcgcagaaaa ggtaagcgtg aaggcgtgca acaaggcata cagcaaggta
    45601 tacatcaagg taagcaggag gaagccttgc gtattgcgca tacgatgctg gaacagggga
    45661 tcgagcgaga gatggtgctg atgattaccg ggctttctga cgaagagatt aaggcaaagc
    45721 gccattaaac ttttccctct tccgcccggt catcgtgatt atcaacggcg ttaagcggcc
    45781 cgcgcgcgtc gacgggaatc gagggagatc agaatcactg acgagagaat gagcagcgtg
    45841 cccagccagt ccggcaaggt aaaactaatc cccaacagca gcagcgacag cagggcgctg
    45901 cttaacggtt ccgcgcagct taaaatgctg gctttggggc caccaatcag ctgcgcgcct
    45961 ttcaaataca ggctgaacgt cagcgacgta ccgatcacca ccaggtagaa aaaggccaga
    46021 atcaggctgc cgctcaccgc aaagtgcgtt ccttctttag cgtagaaggg cagcagaata
    46081 aggccgccaa aggacatact ccagccgacc actggcagcg tgccgtattg ggcgattagc
    46141 ctggaaggcc aggtcgtata aaaggcggcg gcaaatgcgg aggcgatacc ccagaacagc
    46201 gcgcctgaag agatcgacag cgatgttgga ttgccgtgag tcaccagtaa aaaggtgccg
    46261 ataagcgatg taagaatggc ggttaagacc agaatgcctg gtcgtgttct tcgcgctaat
    46321 gcaaaccacg cgacaataat ggtcggcgat aaaaattgca gcactgtcgc ggtggcggca
    46381 ttggattttt caatcgtgag caggaaggtt agctgaacgg tgagcgcgcc caccacggag
    46441 aaaatcagca gactcagtgc atctttgcgg tttttaagaa tcgaaaatat cttatcgccg
    46501 tgcataaagg agaaggtcac cagtatcagc ccggcgaata acaaacgtat catcgtcagg
    46561 aactgtgacg acatacggct ttgctccatg atgtactgcg cgcaaacgcc tgaactcccc
    46621 cacaatacgg cggcaatcag gacgtttagc atcccttttc tggtggaacc cattttttcc
    46681 tcgtcatgtt gttttatttt tttacgtgca ggcatcataa cagagctatc gccggcatta
    46741 agcaggaatt tattgtttaa tgatttcaga cgagcctgtt attgacataa tattgtcatt
    46801 tttttgtcac gggaaatatc aaacaaactt aaacaaatcg tcactatccc cgcctttgca
    46861 ctttacagaa catattgact gactataata agcgcaaatt catgcaggag taatatgttg
    46921 gacagtcact tttacgtaaa tcatctggca agttaacgca cgctattcct gcgctgcttg
    46981 ccgaaccggt gggcagcaat ctccccttgt gacgattgtc atcccaataa tgttacaaca
    47041 cgcgcattgt cgcgaggtaa tcgtcatgtt catgtttaaa cacgctttat ttcctccgcc
    47101 gttaacacga cgctaattgc ctcagggcag aaatttgtcg tgtgctaaat atagcacgta
    47161 cttattcttc cagaaaaaat ggaggaacgt atgttaatgt ttccttatat tttaaattta
    47221 ctggccgcta tgctgttggg cgcgctgatt ggcgcggaaa gacaatggcg tcaacgtatg
    47281 gcgggattac gcactaatgc gctggtggcg acaggcgccg ccgtttttat tctgagctcc
    47341 atgacgacat cgccagacag ccccgggaga attgcggcgc agattgtctc tggtattggc
    47401 tttctggggg cgggcgtcat catgcgcgaa gggatgaatg tgcgcggact gaacactgcg
    47461 gcaacgctat ggtgttcggc gggcatcggc gtgttatgcg gcttagggca gttcaaaaat
    47521 gcactggcgg cgacgatcat tattctttgt gccaatattt tattgcgtga agcggcgcag
    47581 cgtataaatc aactcccggt atccgccgag gcagaaaaac gttatatcct gaaagtaacc
    47641 tgtaataaag aagatgagag cgcggttcgt cagtggttac tgaatatcgt aaaagaggcc
    47701 gcgatctgtt tacaagggtt aggttcggtc cccgctcagg aacagggcta taaagaaatt
    47761 cgtgccgagc tcgtgggtca tgctgattat cgtaaaacgc gagaactgat tatatccaga
    47821 ataggtgata acgataatat caccgcaatt cactggagca ttgatagtca ataatagttt
    47881 tttattcaat tgcaacatta cgccaggcgt ataaggaggg aatgatggat attcccgagt
    47941 cgataaaata aaacccactc aaaatagtga gtaagcaata acctttttta tgcatagata
    48001 attctcccgg ggcattcacc ttcaaatcgt gagtttacta ttccctgggc gtgatatgca
    48061 ggaaacacta caccttaatt ttggggattc atcatgactg acatgaacat tgaaaaccgg
    48121 aaactcaatc gcccggcgtc agaaaatgat aagcagcata aaaaagtatt tccgatcgaa
    48181 gcggaagctt ttcatagccc ggaggagaca ctggcgcggc tgaacagcca tcgtcagggc
    48241 ctcacgatag aagaggccgg cgaacggttg aaagtgtatg ggcgcaatga agtggcgcat
    48301 gagcaagttc ctccggtgct ggttcagctt ctgcaggcat tcaataaccc gtttatttac
    48361 gttctgatgg cactggcagg ggtcagtttc atcacggatt actggctccc gttacgccgt
    48421 ggcgaagaga ccgatctcac cggcgtgctg attattctga cgatggtcag tttgagcggg
    48481 ttattgcgtt tctggcagga gtttcgcact aacagagcag cacaggcgct gaaaaagatg
    48541 gtgcgcacca ccgccacgat gttgcgtcgt gggccgggca atataggcgc ggtgcaggaa
    48601 gagattccca ttgaagaact ggtgccgggc gatgtggttt ttctggccgc aggcgatctg
    48661 gtgcccgccg acgtccgtct gctggcgtcg cgcgatctct ttatcagcca gttaattctt
    48721 agtggtgaat cattacccgt agaaaaatac gatgttatgg ctgatgtggc aggtaaagac
    48781 agcgagcaat tgcctgacaa agataagagc ctgttagatt tgggcaatat ctgtctgatg
    48841 ggaaccaatg taaccagcgg cagagcgcaa gcggtcgtgg tcgcgacggg aagccgtacc
    48901 tggttcggct cgctggcgaa atccattgtg ggtacgcgta cccagacggc tttcgatcgc
    48961 ggagtcaaca gcgtgagctg gctgttgata cgctttatgc tgatcatggt gccggttgtc
    49021 ctgctgatca atggtttcag taagggagac tgggtagagg cttcgctgtt cgcgctggcg
    49081 gttgcggttg ggttgacgcc ggaaatgttg cccatgatag tcagttccaa cctggcaaaa
    49141 ggcgcgattg cgatgtcgcg gcgcaaagtg atcgtcaagc gcctgaacgc tattcaaaac
    49201 ttcggcgcga tggatgtgct gtgtacagat aaaaccggca ccttaaccca ggacaatatt
    49261 tttctggagc atcatctgga tgtgagcggt gtaaaaagca gccgggtatt gatgctggcc
    49321 tggctgaata gtagcagcca gagcggcgcc cggaatgtga tggatcgcgc catactgcgt
    49381 tttggcgagg ggcgaatcgc accatcgaca aaagcgcgct tcattaaacg cgatgaactg
    49441 ccattcgact ttgtacgtcg ccgggtatcg gtcctggtgg aggatgcgca gcatggagac
    49501 agatgtctga tctgtaaagg cgccgttgaa gagatgatga tggtagccac ccatcttcgc
    49561 gaaggcgatc gtgtggtggc gctgacggaa acacgccgcg agctgctgct ggcgaaaacc
    49621 gaagattaca atgctcaggg attccgtgta ttgctgatag cgacacgtaa gctggatggt
    49681 tccgggaaca atccgacatt aagtgtggag gatgagaccg aacttaccat cgaagggatg
    49741 ctcacttttc tcgatccgcc gaaagagagc gccggaaaag ctattgccgc gttgcgggat
    49801 aacggcgtgg cggtcaaagt cctcaccggc gataatccgg tcgtgacggc gcgtatctgt
    49861 ctggaagtgg gtattgatac gcacgatatc ctgatcggaa cccaggttga ggcgatgtcg
    49921 gatgccgaac tggcgtctga agtggagaaa cgcgcagtat tcgcccggct gacgccgtta
    49981 caaaaaacgc gtattttgca agcgctacag aaaaatggtc ataccgttgg ttttcttgga
    50041 gatgggatca acgacgcgcc cgcgcttcgt gatgcggatg tgggaatttc cgtcgatagc
    50101 gccgccgata ttgctaaaga gtcatcagat attattctgc tggaaaaaga tctcatggtg
    50161 cttgaggaag gcgttatcaa agggcgggaa acctttggca atatcattaa atatctgaat
    50221 atgaccgcca gctctaattt cggcaatgtt ttttcggtac tggtagccag cgcgtttatt
    50281 ccgtttctgc cgatgctggc gattcatctg ttgatccaga atttgatgta cgatatttcg
    50341 cagttgtcgt tgccgtggga caaaatggat aaagagttcc tgcgtaagcc gcggaaatgg
    50401 gacgcgaaaa atattggtcg ttttatgcta tggattggcc caacgtcttc tattttcgat
    50461 atcacaacct ttgcgctgat gtggtacgtt tttgcggcta ataacgtaga ggcgcaggcg
    50521 ctctttcagt ccggctggtt tattgagggg ctgctctcgc agacactggt cgtgcatatg
    50581 ctaaggacgc agaaaatacc gtttatccaa agtcgggcga cgttgccggt attattgacg
    50641 accggcttga ttatggcgat aggcatttat attccattct cacctctggg cgcgatggtt
    50701 ggactggagc cgctgccgct gagctacttc ccgtggttgg tggcgacatt attgagctac
    50761 tgtctggtgg cgcaaggcat gaaacgcttt tatatcaaac gctttggcca gtggttttaa
    50821 taatgtttga ggatcgccca gatgaatcgc tcacccgata aaatcatcgc gctgatattt
    50881 ttactgatta gcctgttggt gttgtgttta gccctctggc aaatcgtttt ctaacgaggt
    50941 gacgccatgc aaaaaagagg gttggacaaa attttttatc aggttgtcct gatagcaatc
    51001 atcctgattt tactgactat ctggatacga taagctgccg ttggcgagcc ccgcttaaaa
    51061 taagaatcga tgtagttgtt ctttttatgg cggggcgcta ttttcatggt atcccacatg
    51121 agaagggcaa tatcatgaat aatcgtcgtg gtttaaccgc cgtcctggcg acgttgatta
    51181 cgttttccct gagcgctacg cctgtgctgg cgaatccggg aaatggcaat ggcggcggac
    51241 atggtaataa cgcggctaat cagggtaata acggtaacgg acataaagga aatgccgggc
    51301 aaaaaacgga acaccgtaaa aatggcggta aaccggatca cgtcgagtcg gacattagct
    51361 acgctgtcgc caggcaactg gcagtgaatt tagggctgac gggttatcag tctttacctc
    51421 cggggattgc gaaaaatctg gcgagaggaa aaccgctgcc gccgggaatc gctaaaaaac
    51481 ggtgccggcg tctatgctgg gacaattacc ttattatccg ggctatgagt ggaaaatcgt
    51541 tggggataat ctggtgctga tcgcgctcag taccgcggtg gtcacggcga ttattaatgg
    51601 cgtatttgat taagagccta tcccaccagg cgttattggc gcagccagtt tggacacgga
    51661 cagcgcgcaa aaaccggagc gtacacgtag tacgtgaggt ttgactcgct acgctcgccc
    51721 ttcgggccgc cgcaagcggc gttcaaaacg ctaacgcgtt ttggcgagca ctgcccaggt
    51781 ccaaaatggc aagtaaaata gccccaatgg gataggctct aagcgtgttg tagtccgatg
    51841 acatggcgct catctactgg ttgtaggctg aataaacagg cgatagataa aatagcccca
    51901 ttaaatgggg ctatttagcc gcttcagggc gttatttatg cgcgttgaga atccagcagt
    51961 tcattatttt ttactacttc ctgcgctttg gtataacttt caatcagtag ctgataggcc
    52021 gggaatattt tggtatatac atccgcccat tctgcggcat cttcccgatt ccaggtacgt
    52081 tgcagctcag aggctaccgc cgcggtatcc attggtacta cgcccgcctg caccacgcgg
    52141 gccatcgtaa tttcctgcgc cattttactg tacgtaccgg aggcatcaat taccgcaaat
    52201 accttgtacc cttccgcgac ggcgctgatg gctggaaaag ccatgcagac actggtaata
    52261 gtaccggcga tgatcagcgt tttacggcct gtcgctttta ccgcctgtac aaaatcggca
    52321 ttatcccagg cattaatttc ccctttacgc gcgacatatt gcgcgtgggg cgcattcgca
    52381 tggatttccg gaatcagcgg accatttggt ccctgtggta cggatgcggt agtaatgacc
    52441 ggcatattgc ataaggtagc gattttagcc agcgccgcgg cgcgcgcgcg taattccggc
    52501 atcggcatgt cgccgacggt ctgaaacagg ccactttggt ggtcaatcag cagcatgact
    52561 gcgtcgttag catcaatggc agggcgttga ccgttaaaat tcgcgggtgt agacataatt
    52621 cattccttgt tgttgccttt cactgatagt cactatcagt gttaaagtca ttaatcgccg
    52681 gggcgatttc cgtttttaag ctgatgacag taatccgttg ccgattctgg attaccctgt
    52741 tgagttcttt ctgaaggaat attcatcggc atcaccttca gtcaatttac tttc
//
LOCUS       DAJVBX010000008        50839 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.008, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000008 DAJVBX010000000
VERSION     DAJVBX010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 50839)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50839)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50839
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.008"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            154..1257
                     /locus_tag="OPV72_000406"
     CDS             154..1257
                     /locus_tag="OPV72_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase small subunit"
                     /protein_id="HCR9912806.1"
                     /translation="MQTQDTFYQVMRRHGVTRRSFLKFCSLTATSLGLSSSMIPQIAY
                     ALENKPRTPVIWLHGLECTCCTESFIRSAHPLAKDAILSLISLDYDDTIMAAAGQQAE
                     QALADVMREYKGNYIVAVEGNAPLNEDGMFCILAGEPFLEKLKRVSADAKAIIAWGSC
                     ASWGCVQAARPNPTKATPVHKLITDKTIIKVPGCPPIPEVMSAVITYMLAFDRIPPLD
                     RLGRPKMFYGQRIHDKCYRRAHFDAGQFVEAWDDEGARKGYCLYKMGCKGPTTYNACS
                     TVRWNDGVSFPIQSGHGCLGCSEDGFWDYGSFYSRATGIPQTGIEATADKIGLGVAGV
                     AGAAAIAHATVSAIKHARNKNNTSSENATEKKK"
     gene            1260..3062
                     /locus_tag="OPV72_000407"
                     /pseudo
     CDS             1260..3062
                     /locus_tag="OPV72_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460498.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-dependent hydrogenase large subunit"
     gene            3013..3756
                     /gene="cybH"
                     /locus_tag="OPV72_000408"
     CDS             3013..3756
                     /gene="cybH"
                     /locus_tag="OPV72_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni/Fe-hydrogenase, b-type cytochrome subunit"
                     /protein_id="HCR9912807.1"
                     /translation="MLLIIMEGSWSGFRYDDDDSEVSMHLKEITSQGYYIYEAPVRLW
                     HWITALSIVVLAVTGYFIGRPLPSIQGEATFMFWMGWIRLIHFTTAYIFTVALLFRIY
                     WACVGNEYAREMFLVPFWRRAWRKGVISEIRWYFFLEKEAHRYYGHNPVAGLAVMFYF
                     WMSVLMVCSGFALYGEGLGTDSWAYQWFGWMIRLTGNDSLALHFWHRLGMWFIIAFVI
                     AHVYTAIREDIMSRQSVISVMISGWRWFR"
     gene            3762..4370
                     /gene="hybD"
                     /locus_tag="OPV72_000409"
     CDS             3762..4370
                     /gene="hybD"
                     /locus_tag="OPV72_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HyaD/HybD family hydrogenase maturation
                     endopeptidase"
                     /protein_id="HCR9912808.1"
                     /translation="MAEVTILGLGNLLWADEGFGVRAAEKLFEQYADNEKVDVVDGGT
                     QGLALLPWLQQTEKLLIMDAIDFGMAPGSLAMFRDEQVPAYLTAKKLSLHQTSFSEVL
                     ALLQLTGGQLSEIVLIGVQPECLDDYGGSLTPQVRAQLMPAVYLAQEVLAQWGITASS
                     AALPTERLNHYSLCMERYEDERPDAQSACRVGDIRVLQREKS"
     gene            4370..4669
                     /gene="hypC"
                     /locus_tag="OPV72_000410"
     CDS             4370..4669
                     /gene="hypC"
                     /locus_tag="OPV72_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HypC/HybG/HupF family hydrogenase formation
                     chaperone"
                     /protein_id="HCR9912809.1"
                     /translation="MCIGVPVQVISPGQWFAKCRDRHGELIDVDIRLVAPPLAGAWLL
                     TFGGAARREMDEAEAVEVLVALDSLEQAMLTQSDPLTGFADLLSRTPELPEHLKK"
     gene            4666..5076
                     /locus_tag="OPV72_000411"
     CDS             4666..5076
                     /locus_tag="OPV72_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase"
                     /protein_id="HCR9912810.1"
                     /translation="MTISPQNPVCPLADKGFLVTDAQTLPSLINAHPTLLVLLQSDPN
                     KHPEVADSWVIIPEILKQFPATSYTAAFADSEQSELIAREYRILKYPALLFFRQHRFV
                     GSLAGLYSWQEYSQRVAALLTTPGYRQDIPVITQ"
     gene            5094..6155
                     /locus_tag="OPV72_000412"
     CDS             5094..6155
                     /locus_tag="OPV72_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubredoxin"
                     /protein_id="HCR9912811.1"
                     /translation="MNHSRTIPVVNIAGPGSQPEEEDFNFLPIPAGINLPLTPVLPEQ
                     ALPAELRVARHILTTLIRDMDNPVATLPFPLSYKLNATEQQNSGLLDQLLGEGEISAR
                     VLLSDGKEQRIQETVFTGVWRVREYNTDQQRVADEIIIGPIPESIWQTHPQPPITPEL
                     PPQLAGLMNGAFIAHEIAERVKQPVKEPHIINLTLLPVNDADREYLDHFLGEGCSAIF
                     SRGYGKCRIVSTHFPGVWRVNYFNDMNTLLQDMIEIADIPDIAVAGIDDIEDAYTGLK
                     NTLEWLKEYPVTENEPVVRMECKVCWWVYDPALGDDVWQIPPGVPFNQLPDYWCCPVC
                     ETSKSGFMVIDEGNNSCKD"
     gene            6143..6913
                     /locus_tag="OPV72_000413"
     CDS             6143..6913
                     /locus_tag="OPV72_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001189412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP/GTP-binding protein"
                     /protein_id="HCR9912812.1"
                     /translation="MQRLTVYSHPLWITWQEAPIGRLLQGATPVYAKTLISRLFTLCA
                     QAHNAAAALLLFPEEKPDMQAAQQELARETLRRALTDWLPLFSHRQATAEEWALLRRG
                     ELSPLASTIFFDDDPQTWLAAGVKGWEAWFLQERSETARWLAAVQNIITPTLPMASSP
                     DHTLITHGPLDVSPLAIEYPLLSACCLSGKTTALRLLARCITLARSLSALPTLRWNRF
                     DDGEWKIAVVETARGWLVHQARLTTSGNITKFRQYVSP"
     gene            complement(6881..7297)
                     /locus_tag="OPV72_000414"
                     /pseudo
     CDS             complement(6881..7297)
                     /locus_tag="OPV72_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460490.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="porin"
     gene            8015..8557
                     /locus_tag="OPV72_000415"
     CDS             8015..8557
                     /locus_tag="OPV72_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HCR9912813.1"
                     /translation="MGITIMQKTSLFFSAAAITLTLMASSASAATPTAAQNEATSTVK
                     QEITESINRYLYSIDKADPTLGKQLFYVSPETSFIHPRGHERGWSQIAENFYGTTMGK
                     TFSKRTLKLDAPPAIHVYGNAAVAEFDWHFTAVRRDNGQTQHTTGRESQVWAKIPNTG
                     WRIVHVHYSGPAKTGVGEGY"
     gene            complement(8613..9527)
                     /locus_tag="OPV72_000416"
     CDS             complement(8613..9527)
                     /locus_tag="OPV72_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416037.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bestrophin family protein"
                     /protein_id="HCR9912814.1"
                     /translation="MIVRPQQHWIRLIFVWHGSVLSKIFSRLLLNFLLSIAVIIMLPW
                     YTMLGIKFTLAPFSILGVAIAIFLGFRNNACYARYVEARHLWGQLMIASRSILREVKT
                     TLPDERGIEDFVRLQIAFAHCLRMTLRRQPQTQVLGNYLDQEALQKVVASHSPANRIL
                     LLMGEWLAIRRRSGKLSDILFHSLNNRLNDMSSVLAGCERIANTPVPFAYTLILHRTV
                     YLFCIMLPFALVVDLHYMTPFISVLISYTFIALDALAEELEDPFGTENNDLPLDAICN
                     AIEIDLLQMNDERDIPAKRIPDKRYQLT"
     gene            complement(9783..10142)
                     /locus_tag="OPV72_000417"
     CDS             complement(9783..10142)
                     /locus_tag="OPV72_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4186 domain-containing protein"
                     /protein_id="HCR9912815.1"
                     /translation="MNALEPLFARLARSTFRSRFRLGIKERQYCWDKGAEVIDKHAAD
                     FIAQRLVPAHPANDGKQTPMRGHPVFIAQHATATCCRGCLAKWHQIPQGEPLSKAQQQ
                     YIVSVIHYWLVIQMNQR"
     gene            complement(10142..11068)
                     /gene="glsB"
                     /locus_tag="OPV72_000418"
     CDS             complement(10142..11068)
                     /gene="glsB"
                     /locus_tag="OPV72_000418"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase B"
                     /protein_id="HCR9912816.1"
                     /translation="MARAMDNAILETILQRVRPLIGQGKVADYIPALASVEGSKLGIA
                     ICTVDGQHYQAGDAHERFSIQSISKVLSLVMAMRHYPEEEIWQRVGKDPSGSPFNSLV
                     QLEMEQGIPRNPFINAGALVVCDMLQGRLSAPRQRMLEVARALCGVSDITYDATVARS
                     EFEHSARNAAIAWLMKSFGNFHHDVPTVLQNYFHYCALKMSCMELARTFVFLANQGEA
                     FHLDEPVVTPMQARQINALMATSGMYQNAGEFAWRVGLPAKSGVGGGIVAIVPHEMAI
                     AVWSPELDPAGNSLAGIAALEQLTQTLGRLVY"
     gene            complement(11141..12529)
                     /gene="sad"
                     /locus_tag="OPV72_000419"
     CDS             complement(11141..12529)
                     /gene="sad"
                     /locus_tag="OPV72_000419"
                     /EC_number="1.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate-semialdehyde dehydrogenase"
                     /protein_id="HCR9912817.1"
                     /translation="MTMMTATQALSVNPATGQTLAAMPWANAQEIEHALSLAASGFKK
                     WKMTSVAQRAQTLRDIGQALRAHAEEMAQCITREMGKPIKQARAEVTKSAALCDWYAE
                     HGPAMLNPEPTLVENQQAVIEYRPLGVILAIMPWNFPLWQVLRGAVPILLAGNSYLLK
                     HAPNVTGCAQMIARILTEAGTPAGVYGWVNANNEGVSQMINDPRIAAVTVTGSVRAGA
                     AIGAQAGAALKKCVLELGGSDPFIVLNDADLELAVKAAVAGRYQNTGQVCAAAKRFIV
                     EEGIAQAFNDRFVAAAAALKMGDPLVEENDLGPMARFDLRDELHQQVQASVAEGARLL
                     LGGEKIAGEGNYYAATVLADVTPDMTAFRQELFGPVAAITVAKDAEHALALANDSEFG
                     LSATIFTADDTLAAEMAARLECGGVFINGYSASDARVAFGGVKKSGFGRELSHFGLHE
                     FCNVQTVWKNRV"
     gene            12632..13504
                     /locus_tag="OPV72_000420"
     CDS             12632..13504
                     /locus_tag="OPV72_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCR9912818.1"
                     /translation="MDLTQLEMFNAVALTGSITQAAAKVHRVPSNLTTRIRQLEADLG
                     VSLFIRENQRLRLSPAGHNFLRYSQQILALVDEARMVVAGEEPQGLFSLGALESTAAV
                     RIPALLAGYNQRYPKIQFALTTGPSGAMLDGVLEGKLNAAFIDGPLMHPGLEGIPAYQ
                     EEMMIVAPHGHSVVSRASEVNGYNIYAFRANCSYRRHFESWFHADGATPGTIHEMESY
                     HGMLACVIAGAGIALMPASMLNSMPGHHQVEAWPLAEKWRWLSTWLMWRRGAMTRQLE
                     AFIELLNAQLASAD"
     gene            13620..14810
                     /locus_tag="OPV72_000421"
     CDS             13620..14810
                     /locus_tag="OPV72_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HCR9912819.1"
                     /translation="MTINPVSRKVAWLRVVTLAIAAFIFNTTEFVPVGLLSDIAESFH
                     MQTAQVGIMLTIYAWVVAVMSLPFMLLTSQMERRKLLICLFVLFIASHVLSFLAWNFT
                     VLVISRIGIAFAHAIFWSITASLAIRLAPAGKRAQALSLIATGTALAMVLGLPIGRVV
                     GQYFGWRTTFFAIGMGALITLLCLIKLLPKLPSEHSGSLKSLPLLFRRPALMSLYVLT
                     VVVVTAHYTAYSYIEPFVQNVAGLSANFATVLLLILGGAGIIGSLVFGKLGNRHASSL
                     VSIAIALLVVCLLLLLPAADSEAHLAILSIFWGIAIMVIGLGMQVKVLALAPDATDVA
                     MALFSGIFNIGIGAGALVGNQVSLHWSMSAIGYIGAIPACAALVWAVLIFRKWPVTLE
                     EQPH"
     gene            complement(14857..15522)
                     /locus_tag="OPV72_000422"
     CDS             complement(14857..15522)
                     /locus_tag="OPV72_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarC family NAAT transporter"
                     /protein_id="HCR9912820.1"
                     /translation="MMDLFKAIGLGLVVLLPLANPLTTVALFLGLAGNMNSAERNRQS
                     YMASVYVFAIMMVAYYAGQLVMNTFGISIPGLRIAGGLIVAFIGFRMLFPQQKAHESP
                     EAKSKSEELADEPTANIAFVPLAMPSTAGPGTIAMIISSASTVRHGGEFPDWVIMVAP
                     PIIFLAVAVILWGCLRSSGAIMRLVGKGGIEAISRLMGFLLVCMGVQFIINGVLEIIK
                     TYH"
     gene            15781..16215
                     /gene="marR"
                     /locus_tag="OPV72_000423"
     CDS             15781..16215
                     /gene="marR"
                     /locus_tag="OPV72_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiple antibiotic resistance transcriptional
                     regulator MarR"
                     /protein_id="HCR9912821.1"
                     /translation="MKSTSDLFNEIIPLGRLIYMVNQKKDRLLNNYLSPLDITATQFK
                     VLCSIRCAGCITPVELKKVLSVDLGALTRMLDRLLCKGWIERLPNPNDKRGVLVKLTP
                     DGAAICEQCHQRPGQDLHQELTKNLTADEVATLEYLLKKILP"
     gene            16235..16618
                     /gene="marA"
                     /locus_tag="OPV72_000424"
     CDS             16235..16618
                     /gene="marA"
                     /locus_tag="OPV72_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MDR efflux pump AcrAB transcriptional activator
                     MarA"
                     /protein_id="HCR9912822.1"
                     /translation="MSRRNTDAITIHSILDWIEDNLESPLSLEKVSERSGYSKWHLQR
                     MFKKETGHSLGQYIRSRKMTEIAQKLKESNEPILYLAERYGFESQQTLTRTFKNYFDV
                     PPHKYRITNMHGESRYMLPLNHGNY"
     gene            16647..16862
                     /gene="marB"
                     /locus_tag="OPV72_000425"
     CDS             16647..16862
                     /gene="marB"
                     /locus_tag="OPV72_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiple antibiotic resistance protein MarB"
                     /protein_id="HCR9912823.1"
                     /translation="MKMLFPALPGLLLIASGYGIAEQTLLPVAQNSRDVMLLPCVGDP
                     PNDLHPVSVNSDKSDELGVPYYNDQHL"
     gene            complement(16981..17883)
                     /gene="eamA"
                     /locus_tag="OPV72_000426"
     CDS             complement(16981..17883)
                     /gene="eamA"
                     /locus_tag="OPV72_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylserine/cysteine exporter"
                     /protein_id="HCR9912824.1"
                     /translation="MMSRKDGFLALLVVVVWGLNFVVIKVGLHHMPPLLLAGLRFLLV
                     AFPAIFFVARPKVPLTLLLGYGLTISFGQFAFLFCAIKFGMPAGLASLVLQAQAFFTM
                     ALGAFVFSERLQRKQLAGIALAIIGVLVLIEASLNGQHIAMSGFMLTLAAAFSWACGN
                     IFNKKIMQHSPRPAVMSLVVWSALIPILPFLLSSLLLEGADHITQSLITIDMTTILSL
                     LYLAFVATILGYGIWGTLLGRYETWRVAPLSLLVPVVGLASAAVLLGETLTGMQLAGA
                     VLIMAGLYINVFGFRVRRTARVRG"
     gene            18111..19298
                     /gene="ydeE"
                     /locus_tag="OPV72_000427"
     CDS             18111..19298
                     /gene="ydeE"
                     /locus_tag="OPV72_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux MFS transporter YdeE"
                     /protein_id="HCR9912825.1"
                     /translation="MNPGLRRSTLALLASSLLLTIGRGATLPFMTIYLNRQYGLGVDL
                     IGYALTSALTIGVIFSLGFGILADKFDKKRYMLLAIIAFACGFIAIPMVHNVVLVVLL
                     FALINCAYSVFSTVLKAWFADNLTATTKTRIFSLNYTVLNIGWTVGPPLGTLLVMQSI
                     NLPFWLAAICSAFPLVFIQVWVTRSVAASEGKNAAIWSPSVLLRDKALLWFTLSAFLA
                     SFVGVAFASCISQYVMVVADSGFAEKVVAVVLPVNAVIVVSLQYAVGRRLTAVNIRPM
                     MTTGTVFFIAGLIGFIFSGDNLFFWGLSAAVFTIGEIIYAPGEYMLIDNIAPAGMKAS
                     YFSAQSLGWLGAAVNPLASGVILTTLPAWSLFVVLIIAIVFAWALMLKGMRITPTQQA
                     ITC"
     gene            19546..19641
                     /gene="mgtS"
                     /locus_tag="OPV72_000428"
     CDS             19546..19641
                     /gene="mgtS"
                     /locus_tag="OPV72_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein MgtS"
                     /protein_id="HCR9912826.1"
                     /translation="MLGSINLFIVVLGIILFSGFLAAWFSHKWDD"
     gene            complement(19989..20362)
                     /locus_tag="OPV72_000429"
                     /pseudo
     CDS             complement(19989..20362)
                     /locus_tag="OPV72_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460475.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YdeI family stress tolerance OB fold protein"
     gene            20789..21316
                     /locus_tag="OPV72_000430"
     CDS             20789..21316
                     /locus_tag="OPV72_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo-tetronate isomerase"
                     /protein_id="HCR9912827.1"
                     /translation="MRLEQHDIVTLDEAESVDSLTKKLGDLLVNQKLRLTSAESCPGG
                     KLASALCAAEDTPSFYGVGYVTFTDEAKAKILRVQRHSLAEHTAVSEAVVTEMAQGAK
                     DQAEVNISIAISGYGGPEGGEDGTPAGTVWFAWNINNTTFTSRQHFNGDCQEVLEKCV
                     RFALAELLFLLTKKA"
     gene            complement(21436..21618)
                     /locus_tag="OPV72_000431"
     CDS             complement(21436..21618)
                     /locus_tag="OPV72_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="general stress protein"
                     /protein_id="HCR9912828.1"
                     /translation="MAEHRGGSGNFAEDKEKASEAGRKGGQHSGGNFKNDPQRASEAG
                     KKGGQNSHSGGRKSGN"
     gene            complement(21963..24005)
                     /gene="dcp"
                     /locus_tag="OPV72_000432"
     CDS             complement(21963..24005)
                     /gene="dcp"
                     /locus_tag="OPV72_000432"
                     /EC_number="3.4.15.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000106277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-dipeptidase Dcp"
                     /protein_id="HCR9912829.1"
                     /translation="MSTNPLLDQSMLPYQAPRFDRIKDCHYRPAFDEGVRQKRVEIEA
                     IVNHPAAPDFTNTLLALEQSGALLSRVTSVFFAMTAAHTNDELQRLDEAFSAELAALS
                     NDIYLNSALFARVDAVWQQRHSLGLDDESLRLVDVIHQRFVLAGAQLAEEDKARLKVL
                     NTESATLMSQFNQRLLAASKAGGLAVDDAHCLEGLSPEEMTVAAEAAREKGLEERWFI
                     PLLNTTQQPALATLRDRQTRENLFAASWTRAEKGDAHDTRAIVQRLVEIRRCQAKLLG
                     FPNYAAWKMADQMAKTPQAALSFMRGIVPPARQRVLNEQAEIQNVIDGEQGGYTVQAW
                     DWMFYAEQVRREKYALDEAQLKPYFALNTVLQEEVFWTANQLFGITFVERFDIPVYHP
                     DVRVWEIFDSDGVGMALFYGDFFARDSKSGGAWMGNFVEQSTLNETRPVIYNVCNYQK
                     PVDGQPALLLWDDVITLFHEFGHTLHGLFAVQRYATLSGTNTPRDFVEFPSQINEHWA
                     SHPRVFERYARHVDSGEKMPADLQERMRKASLFNKGYDMTELFGAALLDMRWHMLEES
                     VAEQSVAEFEQQALAAEHLDLPAVPPRYRSSYFAHIFGGGYAAGYYAYLWTQMLADDG
                     YQWFVEQGGLTRENGQRFRDAILSRGNSTDLETLYSAWRGHEPHIDTILQYRGLDH"
     gene            24144..24890
                     /gene="ydfG"
                     /locus_tag="OPV72_000433"
     CDS             24144..24890
                     /gene="ydfG"
                     /locus_tag="OPV72_000433"
                     /EC_number="1.1.1.298"
                     /EC_number="1.1.1.381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional NADP-dependent 3-hydroxy acid
                     dehydrogenase/3-hydroxypropionate dehydrogenase YdfG"
                     /protein_id="HCR9912830.1"
                     /translation="MIVLVTGATAGFGECIARRFVENGHKVIATGRRHERLQALKDEL
                     GENVLTAQLDVRNRAAIEEMMASLPAQWRDIDVLVNNAGLALGLEPAHKASVEDWETM
                     IDTNNKGLIYMTRAVLPGMVERNRGHIINIGSTAGSWPYAGGNVYGATKAFVRQFSLN
                     LRTDLHGTAVRVTDIEPGLVGGTEFSSVRFKGDDEKAGKTYENTTALTPEDITEAVWW
                     VATLPAHVNINTVEMMPVTQSFAGLSVHRS"
     gene            25020..25706
                     /locus_tag="OPV72_000434"
     CDS             25020..25706
                     /locus_tag="OPV72_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCR9912831.1"
                     /translation="MTVETQLNPTQPVNQQIYRILRRDIVHCLIPPGTPLSEKEVSTR
                     FNVSRQPVREAFIKLAENGLIQIRPQRGSYVNKISLSQVQNGCFVRQAIECAVVRRAA
                     AMITDNQCYQLAQNLHLQHIAIERKQIDDFFQLDDDFHQKLAQIADCQLAWDTIENIK
                     ATIDRVRYMSLDHVSPPEMLLRQHHDIFSALENRDGNAVESAMTQHLQEISESVQLIR
                     QENSGWFSEE"
     gene            25887..26090
                     /gene="ydfZ"
                     /locus_tag="OPV72_000435"
     CDS             25887..26090
                     /gene="ydfZ"
                     /locus_tag="OPV72_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenium delivery protein YdfZ"
                     /protein_id="HCR9912832.1"
                     /translation="MMTYDRNRNAITTGSRVMISGTGHTGIIKAIESEGLDAGQIRRG
                     KTVIVEGCEGKFAPVELIRLGMN"
     gene            complement(26157..27623)
                     /locus_tag="OPV72_000436"
                     /pseudo
     CDS             complement(26157..27623)
                     /locus_tag="OPV72_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460468.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
     gene            complement(27767..29146)
                     /locus_tag="OPV72_000437"
     CDS             complement(27767..29146)
                     /locus_tag="OPV72_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012210164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MHS family MFS transporter"
                     /protein_id="HCR9912833.1"
                     /translation="MTQIKHERSTQDLVRAAVSGWLGTALEFMDFQLYSLGAALVFHE
                     IFFPEQSAAMALILAMGTYGAGYIARIIGAFVFGKMGDRIGRKKVLFITITMMGICTT
                     LIGVLPTYAQIGIFAPVLLVTLRIIQGLGAGAEISGAGTMLAEYAPKGKRGIISSLVA
                     MGTNCGTLSATAIWAVMFFALEREQLIAWGWRIPFLASVVVMIFAIWLRMNLKESPVF
                     EKVSEGEKSPALTPASENTLGAMFTSKSFWLATGLRFGQAGNSGLIQTFLAGYLVQTL
                     LFNKSIPTDALMISSVIGFITIPLLGWLSDKYGRRLPYIILNISAIILAWPMLSIVVD
                     KTYSPGVIMAALIVIHNFAVLGLFALENITMAEIFGSRNRFTRMAISKEAGGLVAVGF
                     GPVLAGIFCNMTDSWLPILIMLVLYSCIGLISALLMPEVRDRDLSLPEDAAEATAAEK
                     LRHSATQTS"
     gene            complement(29200..30063)
                     /locus_tag="OPV72_000438"
     CDS             complement(29200..30063)
                     /locus_tag="OPV72_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Zn-dependent oxidoreductase"
                     /protein_id="HCR9912834.1"
                     /translation="MKSIVIEKPNTLTIETRALLQPASGEVRIKVKLAGICGSDSHIY
                     RGHNPFAKYPRVIGHEFFGVIDAVGDNVNRDRIGERVSVDPVISCGHCYPCSVGKPNV
                     CTSLVVLGVHRDGGFSEYAVAPARNAHRIPDNIADHHAVMVEPFTIAANVTGQVNPTE
                     QDVALIYGAGPMGLTTVQALKGVYQVKTVIVVDRIEESPAARIVLMGFSSDPCEIVQQ
                     GITGKELAIYSSRLNANKFPVVIDWLNKGLIDPDKLITHTFDYQHVTDAIELFEKDQR
                     QCCKVLLTFAK"
     gene            complement(30074..31288)
                     /gene="rspA"
                     /locus_tag="OPV72_000439"
     CDS             complement(30074..31288)
                     /gene="rspA"
                     /locus_tag="OPV72_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="starvation-sensing protein RspA"
                     /protein_id="HCR9912835.1"
                     /translation="MKIVGAEVFVTCPGRNFVTLKITTEDGITGLGDATLNGRELSVA
                     SYLTDHLCPQLIGRDAHRIEDIWQFFYKGAYWRRGPVTMSAISAVDMALWDIKAKAAN
                     MPLYQLLGGASREGVMVYCHTTGHTIDDVLEDYARHKEQGFKAIRVQCGVPGMKTTYG
                     MAKGKGLAYEPATKGQWPEEQLWSTEKYLDFTPKLFDAVRNTFGFNEHLLHDMHHRLT
                     PIEAARFGKCIEDYRLFWMEDPTPAENQECFRLIRQHTVTPIAVGEVFNSIWDCKQLI
                     EEQLIDYIRTTITHAGGITGMRRIADFASLYQVRTGSHGPSDLSPVCMAAALHFDLWV
                     PNFGVQEFMGYSEQMLEVFPHNWTFEGGYMHPGDKPGLGIEFNEKLAAKYPYDPAYLP
                     VARLEDGTLWNW"
     gene            complement(31410..31736)
                     /locus_tag="OPV72_000440"
     CDS             complement(31410..31736)
                     /locus_tag="OPV72_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnfA family protein"
                     /protein_id="HCR9912836.1"
                     /translation="MLKTTLLFFVTALCEIIGCFLPWLWIKRGASVWWLLPAAASLAL
                     FVWLLTLHPAASGRVYAAYGGVYVCTALLWLRVVDGVRLTVYDWSGALIALCGMLIIV
                     VGWGRT"
     gene            31889..32230
                     /locus_tag="OPV72_000441"
     CDS             31889..32230
                     /locus_tag="OPV72_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1283 family protein"
                     /protein_id="HCR9912837.1"
                     /translation="MNNTLSKRLCLTAMLTLAAVVYTTSAFAETSKLVIESGDSAQSR
                     QEAAMEKEQWNDTRSLRQKVNTRAEKEWDKADAAFDNRDKCEQSANINAYWEPNTLRC
                     LDRRTGRVITP"
     gene            32266..32826
                     /gene="speG"
                     /locus_tag="OPV72_000442"
     CDS             32266..32826
                     /gene="speG"
                     /locus_tag="OPV72_000442"
                     /EC_number="2.3.1.57"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine N1-acetyltransferase"
                     /protein_id="HCR9912838.1"
                     /translation="MTSDYKVRLRPLEREDLRFVHQLDNNASVMRYWFEEPYEAFVEL
                     SDLYDKHIHDQSERRFVVECDGENAGLVELVEINHVHRRAEFQIIISPEYQGKGLASR
                     AAKLAMDYGFTVLNLYKLYLIVDKENEKAIHIYRKLGFRVEGELIHEFFINGEYRNTI
                     RMCIFQQQYLDEHKTSSSTLLKPTAQ"
     gene            complement(32867..33577)
                     /locus_tag="OPV72_000443"
     CDS             complement(32867..33577)
                     /locus_tag="OPV72_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnfC family lipoprotein"
                     /protein_id="HCR9912839.1"
                     /translation="MKKPLLLTLLCMILAGCDNPKSPESFTPEMASFSNEFDFDPLRG
                     PVKDFSQTLMSENGEVAKQVTGTLSQEGCFDTLELHDLENNTGLALVLDANYYRDAQT
                     LEKKVQLQGKCQLAALPSAGVTWETDDNGFVVSATGKEMKVEYRYDSEGYPLGKTTIN
                     SQNTLSVTAKLSTDSRKKLDYTAVSRVDDRQVGNVTQSCEYDAYANPVDCRLVIVDES
                     VKPAVSHHYTIKNRIDYY"
     gene            33681..33990
                     /locus_tag="OPV72_000444"
                     /pseudo
     CDS             33681..33990
                     /locus_tag="OPV72_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460460.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1161 domain-containing protein"
     gene            34144..36585
                     /locus_tag="OPV72_000445"
     CDS             34144..36585
                     /locus_tag="OPV72_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase subunit A"
                     /protein_id="HCR9912840.1"
                     /translation="MMPGEKQQTGVSRRTLVKSAALGSLALAAGGVSLPFGMRTAAAA
                     VQQAMRNEEDKIVWGACSVNCGSRCALRLHVKDNEVWWVETDNTGDDVYGNHQVRACL
                     RGRSIRRRINHPDRLNYPMKRVGRRGEGKFERISWQEALDTISASLKKTVEIYGNEAV
                     YIHYSSGIVGGNITRSSPSASPVKRLMNCYGGSLNQYGSYSTAQISCAMPYTYGSNDG
                     NSTSDIENSKLVVMFGNNPAETRMSGGGITWFLEQARERSNARMIVIDPRYTDTAAGR
                     EDEWIPIRPGTDAALVAGIAWVLINENLVDQPFLDNYCIGYDEKTLPADAPPNGHYKA
                     YILGQGEDGIAKTPQWASHITGIPADRIIKLAREIGSVKPAYICQGWGPQRQANGEQT
                     ARAIAMFPILTGNVGIHGGNGGARESTYTITIERLPVLENPVKTAISCFSWTDAIARG
                     PEMTALRDGVRGKDKLDVPIKFLWNYAGNTLINQHSDINKTHEILQDEAKCEMIVVID
                     NFMTSSAKYADILLPDLMTVEQEDIIPNDYAGNMGYLIFIQPATTPKFERKPIYWVLS
                     EIARRLGDDVYQRFTEGRTQAQWLQYLYAKMQARDPALPAYDELKKMGIYKRKDPNGH
                     FVAYKKFREDPQANPLKTPSGKIEIYSSKLAHIASTWELAEGDVISPLPIYTPTFEGW
                     DDPKRSTFPLQLFGFHYKSRTHSSYGNIDVLQAACRQEVWINPLDAQKRGIANGDKVR
                     VFNDRGEVRLPAKVTPRILPGVSAMGQGAWHNADMAGDKIDHGACINTLTTLRPSPLA
                     KGNPQHTNLVEIEKI"
     gene            36687..39122
                     /locus_tag="OPV72_000446"
     CDS             36687..39122
                     /locus_tag="OPV72_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase subunit A"
                     /protein_id="HCR9912841.1"
                     /translation="MKITNPEALMAASISRRSLVKTSAIGSLALASSAFTLPFSRIAH
                     AAADLASGNMAEKAVWSSCTVNCGSRCLLRLHVKDDTVYWVESDTTGNDEYGNHQVRA
                     CLRGRSIRRRMNHPDRLKYPMKRVGKRGEGKFERISWDEALDTIGDNLKRILKDYGNE
                     AVHVLYGTGVDGGNITNSNVPYRLMNACGGYLSRYGSYSTAQISAAMSYMFGGNDGNS
                     PDDIANTKLVVMFGNNPAETRMSGGGVTYYVEQARERSNARMIVIDPRYNDTAAGRED
                     EWLPIRPGTDGALAAAIGWVLITEDLIDKPFLDKYCIGYDETTLPASAPRNAHYKAYI
                     LGQGEDGIAKTPQWAAQITSIPAEKIIQLAREIGSAKPAYICQGWGPQRHSNGEQTAR
                     AIAMLSVLTGNVGINGGNSGVREGTWDLGVEWFPMLENPVKTQISVFTWTDAIDHGAE
                     MTATRDGVRGKDKLDVPIKFLWCYASNTLINQHGDIAHTHEVLQDDSKCEMIVGIEHF
                     MTASAKYCDILLPDLMPTEQEDLISHESAGNMGYVILGQPATSPKFERKPIYWTLSEV
                     AKRLGPDVYQTFTEGRTQHEWVKYLHAKTKARNPEMPDYEEMKQTGIFKKKCPEEHYV
                     AFRSFREDPAANPLKTPSGKIEIYSERLATLANTWELKKDEIIHPLPAYTPGFDGWDD
                     PLRQRYPLQLTGFHYKARTHSSYGNIDVLQQACPQEIWINPIDAQARGIQHGDTVRVF
                     NQNGEMLIPAKVTPRILPGVTAIGQGAWLNADMFGDKVDRGGSINILTSHRPSPLAKG
                     NPSHSNLVQVEKA"
     gene            39133..39750
                     /gene="dmsB"
                     /locus_tag="OPV72_000447"
     CDS             39133..39750
                     /gene="dmsB"
                     /locus_tag="OPV72_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000213046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethylsulfoxide reductase subunit B"
                     /protein_id="HCR9912842.1"
                     /translation="MTTQYGFFIDSSRCTGCKTCELACKDYKDLTPDVSFRRIYEYAG
                     GDWQEDNGVWHQNVFAYYLSISCNHCEDPACTKVCPSGAMHKRDDGFVVVNEEVCIGC
                     RYCHMACPYGAPQYNAAKGHMTKCDGCYDRVAEGKKPICVESCPLRALDFGPIDELRK
                     KHGELAAVAPLPRTHFTKPNIVIKPNANSRPTGDTTGYLANPKEV"
     gene            39752..40606
                     /locus_tag="OPV72_000448"
     CDS             39752..40606
                     /locus_tag="OPV72_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase anchor subunit
                     family protein"
                     /protein_id="HCR9912843.1"
                     /translation="MGSGWHEWPLVLFTVLGQCVAGALIVSGYGWLTTKDDVAKQRIV
                     RSMFFLWLVMGLGFLASIMHLGLPMRAFNSLNRVGASALSNEIAAGSVFFAVGGIWWL
                     VAVLGKMPPALGKVWLLVSMALGVAFIWAMTLVYQIDTVPTWYNGYTTLAFFLTAFLC
                     GPVFAALLLRIARVPFCSVTFASISGLALVVCVAVIVLQGLSLSAIHSSVQQASHLAP
                     DYGMLQVWRIVLLAAGLGCWLCPLIRRREPHTVGLLLGVVLVLAGEIIGRGLFYGLHM
                     TVGMAVAG"
     gene            40649..41263
                     /gene="dmsD"
                     /locus_tag="OPV72_000449"
     CDS             40649..41263
                     /gene="dmsD"
                     /locus_tag="OPV72_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tat proofreading chaperone DmsD"
                     /protein_id="HCR9912844.1"
                     /translation="MTTFLQRDDFAVTARVLGALFYYSPESHETAPLVQALLNDDWQA
                     QWPLDAEALAPVAAMFKTHSEESLPQAWQRLFIGPYALPSPPWGSVWLDRESVLFGDS
                     TLALRQWMRENGIQFEMQQNEPEDHFGALLLLAAWLAENGRHHECEQLLAWHLFPWSP
                     RFLDVFIDHAGHPFYQALGQLARLTLAQWQAQLIIPVAVKPLFR"
     gene            41568..42278
                     /gene="osmY"
                     /locus_tag="OPV72_000450"
     CDS             41568..42278
                     /gene="osmY"
                     /locus_tag="OPV72_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter permease OsmY"
                     /protein_id="HCR9912845.1"
                     /translation="MHILTLKRVLGFTIVILLLLALFIWGIGLETLKARQVDLLYLGQ
                     RHLMLVFTSMFFALLVGIPSGILLSRPAAKGFAEYVMQIFNVGNTLPPLAVLALAMVI
                     IGIGDTPAIVALFLASLLPIVRNTYAGLCSVPASLIEAANGIGMTKWQRLRQVELPNA
                     WPVMLSGIRIATAINVGTAPLAFLIGASSYGELIFPGIYLNDFPTLILGATATALFAL
                     ILDTLLAWFGRRLSPHTV"
     gene            42307..43209
                     /gene="osmX"
                     /locus_tag="OPV72_000451"
     CDS             42307..43209
                     /gene="osmX"
                     /locus_tag="OPV72_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein OsmX"
                     /protein_id="HCR9912846.1"
                     /translation="MRFKKHLLGWLATTLLFSSQTQAAPLVLATKSFTEQHILSAMTV
                     QYLQKKGFQVQPQTNIAAVISRNAMVNKQIDITWEYTGTSLIIFNRIDKRMSPQETYD
                     TVKRLDAKLGLVWLKPADMNNTYAFAMQRKRAESENITTISQMVAKIEQVRQNDPDHN
                     WMLGLDLEFAGRSDGMKPLQQAYQMQLDRPQIRQMDPGLVYNAVRDGLVDAGLVYTTD
                     GRVKGFDLKVLEDDKGFFPSYAVTPVVRKEVLEANPGLDDALNTLSGLLNNDVISTLN
                     AQVDIEHRTPQQVAHQFLQDKGLL"
     gene            43219..43866
                     /gene="osmW"
                     /locus_tag="OPV72_000452"
     CDS             43219..43866
                     /gene="osmW"
                     /locus_tag="OPV72_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter permease OsmW"
                     /protein_id="HCR9912847.1"
                     /translation="MDTIHYMLDNAGYLASLTFQHLWLVALAVGLAIIIGVPLGVLIV
                     RHKWLATPVLGAATLLLTIPSIALFGLMIPLFSLIGHGIGVLPAVTAVFLYSLLPIVR
                     NTHTALDSLPPGLREAGRGIGMTFWQRLRWVEIPMALPVIFGGIRTAVVMNIGVMAIA
                     AVIGAGGLGLLLLNGISGSDIRMLIAGALMICLLAIVLDWLLHRLQVVLAPKGIR"
     gene            43866..45014
                     /gene="osmV"
                     /locus_tag="OPV72_000453"
     CDS             43866..45014
                     /gene="osmV"
                     /locus_tag="OPV72_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter ATP-binding
                     protein OsmV"
                     /protein_id="HCR9912848.1"
                     /translation="MIKLENLTKQFVQKKGQPLKAVDNVNLNVPEGEMCVLLGPSGCG
                     KTTTLKMINRLIAPSSGNILINGENTNDMDTVTLRRNIGYVIQQIGLFPNMTIEENIT
                     VVPRMLGWDKARCKQRAEELMDMVALDARKFLHRYPKEMSGGQQQRIGVIRALAADPP
                     VLLMDEPFGAVDPINREVIQNQFLDMQRKLKKTVMLVSHDIDEALKLGDRIAVFRQGR
                     IVQCASPDELLAKPANEFVGSFVGQDRTLKRLLLVSAGDVTDQQPTITARPSMPLSEA
                     FGIMDDHDIRAITVIDNDGKPLGFVKRREARNASGICADITHPFRITGKAEDNLRIVL
                     SRLYESNTSWMPIVDEDGRYNGEISQDYIADYLSSGRTRRALNIHESS"
     gene            45150..46439
                     /gene="clcB"
                     /locus_tag="OPV72_000454"
     CDS             45150..46439
                     /gene="clcB"
                     /locus_tag="OPV72_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460450.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated ClC-type chloride channel ClcB"
                     /protein_id="HCR9912849.1"
                     /translation="MHRLHAYPDLRAMFRRLLIATLIGILAALAVAAFRHAMQLLEWI
                     FLSNDTGSLVNAAEGLSPWRRLITPALGGLAAGLLLWGWQKMNQQRPHAPTDYMEALQ
                     TDGQFDVGASLVKSLASLLVVVSGSAIGREGAMILLAALAASSFARRFTPREEWKLWI
                     ASGAAAGMAGAYHAPLAGSLFIAEILFGTLMLASLGPVVVSAVVALLTTHVLNGSDSL
                     LYTVHLTVDLYAREYVMIVSTGLVAGLWGPLLMWLMTASHNSFLRLKLSPPWQLALGG
                     LIVGLLSLLTPTVWGNGYSVVQSFLLSPPLFSLIGGIFACKILAVLASSGSGAPGGVF
                     TPTLFVGLSIGMFLGRIWGFWLPGSDEIAILLGLAGMATLLAATTHAPIMSTLMICEM
                     TGEYQLLPGLLIACVVASVLSRTLRHDSIYRQHAAEH"
     gene            complement(46395..47090)
                     /gene="bioD"
                     /locus_tag="OPV72_000455"
     CDS             complement(46395..47090)
                     /gene="bioD"
                     /locus_tag="OPV72_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent dethiobiotin synthetase BioD"
                     /protein_id="HCR9912850.1"
                     /translation="MLKRFFITGTDTSVGKTVVSRALLQALSSGGKSVAGYKPVAKGS
                     KETPEGMRNKDALVLQSVSSLELPYEAINPIALSEEESSVAHSCPINYTLLSNGLASL
                     SDKVDHVVVEGTGGWRSLMNDLRPLSEWVVQEQLPVLMVVGIQEGCINHALLTAQAVA
                     NDGLPLIGWVANRINPGLAHYAEIIDVLGKKLPAPLIGELPYLPRAEQRELGQYIRLS
                     MLGSVLAVDRIMA"
     gene            complement(47216..48436)
                     /locus_tag="OPV72_000456"
     CDS             complement(47216..48436)
                     /locus_tag="OPV72_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HCR9912851.1"
                     /translation="MVADSQPGHIDQIKQTNAGAVYRLIDQLGPVSRIDLSRLAQLAP
                     ASITKIVREMLEAHLVQELEIKEAGSRGRPAVGLMVETEAWHYLSIRISRGEIFLALR
                     DLSSKLVVEECLALPLNEATPLLERIITHVDRFFTRHQQKLERLTSIAITLPGIIDTE
                     NGVVHRMPYYEDVKEMPLGDALERHTGVPVYIQHDISAWTMAEALFGASRGARDVIQV
                     VIDHNVGAGVITDGHLLHAGSSSLVEIGHTQVNPYGKRCYCGNHGCLETIASVDSVLE
                     LTQLRLNQSISSMLHGQPLTVDSLCQAAMQGDLLAKDIISGVGAHVGRILAIMVNLFN
                     PQKILIGSPLSKAADILFPAIADSIRQQALPAYSRNTVVESTQFTNQSTMAGAALVKD
                     AMYNGSLLIRLLQG"
     gene            complement(48564..49463)
                     /locus_tag="OPV72_000457"
     CDS             complement(48564..49463)
                     /locus_tag="OPV72_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCR9912852.1"
                     /translation="MNIELRHLRYFVAVAEELHFGRAAARLNISQPPLSQQIQILEQQ
                     VGARLLARTNRSVALTAAGRQFLADSRHILSLVNDAAARAERLHQGEAGEIRIGFTSS
                     APFIRAVSHTFSLFRQSYPGVHMQTREMNTREQIAPLNEGVLDIGLLRNTPLPDTLNR
                     EVILHEPLMAMIPREHRLAQKPVVSLTELAEEPFVFFDPHVGTGLYDDILGLMRRYNL
                     SPTITQEVGEAMTIIGLVAAGLGVSILPASFKRVQMSEMRWVPLAEEDAVSEMWLVWP
                     KHHEQSHAVQRFCQLLLLAARQD"
     gene            49583..50836
                     /locus_tag="OPV72_000458"
     CDS             49583..50836
                     /locus_tag="OPV72_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR9912853.1"
                     /translation="MSRTTILDDATASDIDEQRHSQPVQFIKRGTAPFMRVTLALFSA
                     GLATFALLYCVQPILPVLSQEFGVSPASSSVSLSISTAMLAIGLLFTGPLSDAIGRKP
                     VMVTALLLASCCTLLSTMMTSWHGILIMRALIGLSLSGVAAVGMTYLSEEIHPSFVAF
                     SMGLYISGNSIGGMSGRLLSGVMTDFFNWRIALAAIGCFALASALMFWKILPASQHFR
                     PTSLRPKTLFINFRLHWRDRGLPLLFAEGFLLMGAFVTLFNYIGYRLMLSPWELSQAV
                     VGLLSVAYLTGTWSSPKAGAMTSRYGRGPVMLFSTAVMLGGLLLTLFTSLWLIFAGML
                     LFSAGFFAAHSVASSWIGPRARRAKGQASSLYLFSYYLGSSIAGTLGGVFWHSYGWNG
                     VGGFIALMLVLAILVGTRLHHRLHA"
BASE COUNT        12387 a        13611 c        12745 g        12096 t
ORIGIN      
        1 ttaaattaat ttatgttttt gagtaatgtg agtagcacac atgtaatcag ttgttacgaa
       61 ttagaaacat aattgctact aaaacacgtt gagaaagaca agaaatgcaa catatgatgc
      121 ccacactaac tatagtggtt tgggataaac gttatgcaaa cacaagatac attttatcaa
      181 gttatgcgta gacacggcgt gacaaggcgt agcttcctca agttttgcag ccttaccgca
      241 acgtctttag gcctgagcag ttcgatgatt cctcagatag cttatgccct ggagaataaa
      301 ccgcgtacgc cagtgatatg gctgcatggt cttgaatgta cctgctgtac cgaatctttc
      361 attcgctctg cgcacccgtt ggcaaaagat gccattttgt cgctcatttc cctggattat
      421 gacgacacca ttatggccgc cgcagggcaa caagccgagc aggcgttggc ggatgtgatg
      481 cgtgagtaca aaggaaatta tatcgttgcc gtggaaggta acgcgccgct gaatgaagat
      541 ggaatgtttt gcatactggc tggcgagccg ttcctggaaa agttaaaacg cgtcagcgcg
      601 gatgctaaag cgattatcgc ctgggggtcc tgcgcatcat ggggctgcgt gcaggcagcc
      661 cgtcccaacc caactaaagc cacgccggtt cacaaattaa ttaccgataa aaccattatt
      721 aaagtgccag gctgtccgcc tatacctgaa gtgatgtccg ccgttatcac ctatatgctg
      781 gcatttgatc gcatccctcc ccttgatcgt cttggacgac ccaaaatgtt ttatggccag
      841 cgaattcatg acaaatgtta ccgacgcgcg catttcgatg ccggtcagtt tgtggaagcg
      901 tgggatgacg aaggcgccag aaaagggtat tgcctgtaca agatgggctg taaaggcccg
      961 actacctata acgcctgttc aaccgttcgc tggaatgatg gcgtgtcttt tcctatccag
     1021 tcgggtcatg gatgcctcgg atgttcggaa gatggattct gggattacgg ttctttttac
     1081 agccgggcaa cgggcattcc gcaaaccggc attgaggcta ccgccgataa aatcggactg
     1141 ggcgttgccg gcgtcgcggg cgctgctgcc atcgctcacg ccacggttag cgccataaaa
     1201 cacgcccgca ataaaaacaa cacgtcatca gaaaacgcta cggaaaagaa aaaataatta
     1261 tggcatatcc ttatcagact cagggtttta cgctggacaa tagcggacgg cgaattgtgg
     1321 tcgatccggt tactcgcatc gaagagcata tgcgctgcga agtgaatatt gacagtaata
     1381 atgtcattac taacgccgtg tcgaccggca ccatgtggcg cggcctggag gttatcctga
     1441 aaggtcgcga tccgcgagac gcctgggcat ttgttgagcg catttgcggc gtctgcaccg
     1501 gtacacacgc gctgacctca atccgtgccg tagaaaatgc gctgggaatc gcgattccgg
     1561 acaacgcaaa ctgtatccgt aatatgatgc aggctacgct acacgttcac gatcacctgg
     1621 tgcattttta tcatctgcat gcgctggact gggtcgatgt agttgccgcc ctgaaagccg
     1681 acccgcatca gacctccgcc atcgcgcaaa gcctttccgc atggccgcta tcctcgccgg
     1741 gatatttccg cgatttgcaa aatcgactga agcggtttat cgagtccggt taacttggcc
     1801 ctttccgtaa cggctactgg ggacatccgg cgatgaaact tccaccggaa gccaatttgc
     1861 tggcggtcgc ccactatctt gaagcgctcg attttcaaaa agagatcgta aaaattcaca
     1921 ccgttttcgg tggtaaaaac ccgcatccta actggctggt gggcggcgtt ccttgcgcca
     1981 tcaaccttga cgaaacgggc gcggtcggcg cagtgaatat ggagcgcctg aaccttgtca
     2041 gttccatcat ccaaaaagct cgccagttct gcgaacaagt ttatcttccg gacgtcttgc
     2101 tgattgccag ttattacaaa gactgggcaa aaatcggcgg cgggttatcg agcatgaacc
     2161 tgctggctta tggcgagttt ccggataacc ctaacgatta ttccgccagt aatcttctgc
     2221 ttccgcgtgg ggctatcatt aacggtcgtt tcgacgaaat tcatcctgtc gatttaaccg
     2281 cccccgatga gattcaggag tttgtcactc actcctggta tacctatggt aacggcaata
     2341 acgataaggg cctgcatccg tgggatggtc tgaccgaacc gcaactggtc atgggcgaac
     2401 actataaagg cacaaaaacc tttatcgaac aggtggatga gtccgccaaa tattcatgga
     2461 ttaaatcgcc gcgctggaag ggacatgcga tggaggtagg tccgctggcg cgttatttga
     2521 ttggatatca tcaaaataaa ccggaattta aagaaccagt ggatcaactg cttagtgtat
     2581 taaagctgcc taaagaagcg ctcttttcta cattagggcg tactgccgcg cgtgcgctgg
     2641 aatccgtatg ggcaggcaat acgctgcaat atttcttcga tcgtctaatg cgtaacctca
     2701 agtccggcga tacggcgacg gcaaacgtta cgctctggga acccgatacc tggcccacat
     2761 cggcaaaagg cgttggtttc agcgaggcgc cgcgcggcgc gctggggcac tggataaaaa
     2821 ttgaaaatca gaaaatcgac agctatcagt gtgtggtacc gacaacctgg aatgccgggc
     2881 cacgtgacga taaaggtcaa attggcgcgt acgaagcagc gttaatgggg actaaactcg
     2941 ccgttcccga tcaaccattg aagattttac gtactctgca cagcttcgat ccctgcctgg
     3001 cctgctccac ccatgttatt gataatcatg gaggggagct ggtcagggtt caggtacgat
     3061 gacgacgatt cggaggtctc aatgcatctc aaagaaataa ccagccaggg gtactatatc
     3121 tatgaagcgc cggtccgttt atggcactgg atcacggcgt tatccattgt cgtcctggct
     3181 gttacaggat atttcattgg ccgccccctg ccatcgattc aaggtgaagc gacctttatg
     3241 ttttggatgg gctggatacg actgatccat tttaccacgg cgtatatttt tactgtcgcg
     3301 ctgctgtttc gtatttactg ggcatgtgtc ggcaatgagt acgccaggga gatgtttctg
     3361 gttccattct ggcgccgcgc ctggcgcaaa ggcgttatca gcgaaatccg ctggtatttt
     3421 ttcctcgaaa aagaggccca tcgttactat ggacataatc cggtagcggg actggcggta
     3481 atgttctatt tctggatgtc cgtactgatg gtgtgtagcg gctttgcgct ctatggcgaa
     3541 ggacttggaa cagacagttg ggcgtatcaa tggtttggct ggatgattcg cctgactggc
     3601 aacgatagcc tcgcgctgca tttctggcac cggctgggca tgtggttcat tatcgccttc
     3661 gtcattgcgc atgtttatac cgctatccgc gaagacatta tgagccgaca aagcgtgatt
     3721 tccgtcatga taagcggctg gcgctggttc aggtgataac aatggcagaa gtaacaatct
     3781 tagggcttgg caacctgctt tgggcagatg aagggttcgg cgtcagagct gcggaaaagc
     3841 tgtttgaaca gtatgccgat aacgagaaag ttgacgttgt tgatggcggt acgcaggggc
     3901 tggcgctgct gccctggctg caacagacag aaaaactgtt aatcatggat gctatcgatt
     3961 ttggtatggc gccaggttcg ctggcgatgt ttcgtgatga acaggttccc gcctatctga
     4021 cggcgaaaaa acttagttta catcagacca gtttttctga agtgctggca ttgctgcaat
     4081 taaccggcgg ccagttatcg gagattgtgc tgattggcgt gcagccggaa tgtctggatg
     4141 actatggcgg gagtcttacg ccgcaggtaa gggcgcaact gatgcctgcg gtctatctcg
     4201 cgcaggaagt gctggcgcaa tggggtatca ccgcctcttc agcggccttg cccactgaaa
     4261 gactcaatca ttacagcctg tgtatggaac gctacgaaga tgaacggcca gatgcgcaaa
     4321 gcgcttgccg ggtcggcgat attcgggtgc tacagagaga gaaatcataa tgtgtattgg
     4381 cgttcctgtg caggttattt cacccggtca gtggttcgcc aaatgccgcg accgacacgg
     4441 cgagcttatc gacgttgata ttcggcttgt ggctcccccc ttagcaggcg catggctgct
     4501 gacatttggc ggcgcagcgc gacgagaaat ggacgaagcg gaagccgttg aggtactggt
     4561 ggcgctggac tcgctggaac aggccatgct cacgcaaagc gatccgctga ccggttttgc
     4621 cgatttattg tctcgcacgc ctgaattacc ggagcattta aaaaaatgac tatctcaccc
     4681 caaaatcctg tttgtccact ggcggataaa ggctttctgg ttaccgatgc gcaaacgctc
     4741 ccgtcgttga ttaatgcgca tccgactctg ctggttttgc tgcaaagtga ccccaacaaa
     4801 catccggaag tcgccgacag ttgggtcatt atcccggaga tcctcaagca atttccggcg
     4861 acatcttata ccgcggcatt tgcggatagc gaacagagtg aactgatcgc ccgggagtat
     4921 cgcattctga aatatccggc gctgcttttc tttcgccagc accgttttgt cggcagtctg
     4981 gcgggattat atagctggca agaatactct cagcgggtgg ccgcattgct gactacaccg
     5041 ggctatcgtc aggatattcc cgttattacg caatagaatg aaaggtaaca cacgtgaatc
     5101 attccagaac tattccagtc gttaatattg ccggaccagg atcgcagcca gaagaggaag
     5161 actttaactt tcttcccatc cccgccggca ttaatctccc gctgacgccg gttttaccgg
     5221 aacaggcgct gcccgctgag ctccgtgttg ccagacacat cctgactacg cttattcgcg
     5281 atatggataa cccggtggca acgctcccct ttcccctgag ctataagctg aatgccactg
     5341 agcaacagaa tagcggttta ttggatcaac tgctcggcga aggtgaaatc tccgcccggg
     5401 tactattatc cgatggaaaa gaacagcgta ttcaggagac ggtttttacg ggcgtctggc
     5461 gtgtacgtga atataacact gaccagcaac gggttgccga tgaaattatc attggcccga
     5521 tcccggagag catctggcag acgcatccgc agccgccgat tacaccagaa ttgccgccac
     5581 aactggcggg attgatgaat ggcgccttta tcgcgcatga aatagccgag cgcgtaaaac
     5641 agccggtaaa agagccgcat atcattaatt taacgctatt gccagtaaac gatgccgatc
     5701 gcgagtatct ggatcatttt ttaggcgaag gctgtagcgc tattttttca cgcggatatg
     5761 gtaaatgccg gattgtaagc acgcattttc ccggcgtatg gcgggtcaat tatttcaatg
     5821 atatgaacac attactgcaa gatatgattg agatagcgga cattcctgat atcgccgttg
     5881 caggcatcga cgatatcgaa gatgcctaca cggggctaaa aaatacgttg gaatggttga
     5941 aagaataccc ggtcacagaa aatgagccag tggtgcgcat ggagtgcaaa gtatgttggt
     6001 gggtttacga ccctgcgctg ggcgatgatg tatggcaaat tccacccggc gtgcccttca
     6061 accagttacc tgattactgg tgctgtccgg tttgcgaaac cagtaagtcc gggtttatgg
     6121 tgatcgatga aggtaataat tcgtgcaaag attgaccgtc tattctcacc cgctatggat
     6181 tacctggcag gaggcgccga tcggtcgttt gttacagggc gcaacgccgg tatacgcaaa
     6241 aacgcttatt tcacgtttgt ttacgttgtg cgctcaggcg cacaacgcag cggcggcttt
     6301 actgttgttt cctgaagaga agccagatat gcaggccgca caacaagagt tggcgcgaga
     6361 aacgctccgt cgcgcgttga ccgactggct ccccctgttt agccaccgac aggcaaccgc
     6421 tgaagaatgg gcgttgttac gtcgcggaga gttatccccg ctggcaagca caatcttttt
     6481 tgacgatgat cctcagacct ggcttgccgc tggcgtaaag ggctgggaag cctggttttt
     6541 gcaagagcgt tctgaaaccg cccgctggct ggcggcagta cagaatatca ttacacctac
     6601 actaccgatg gcgtcgtccc cggaccatac gttaataacc catggtcccc tggatgtctc
     6661 gcctctggct atcgaatatc cgctgctgtc agcctgttgt cttagcggaa aaacgactgc
     6721 gctacgtctg ctggcccgct gcattacgct cgcccgaagt ttgagcgccc ttcctaccct
     6781 acgctggaat cgttttgatg atggcgagtg gaaaatagca gtagtggaaa ccgcgcgagg
     6841 atggttagtt catcaggcca gactgacgac gtcaggtaat attaccaaat tcaggcagta
     6901 cgtcagtcca tgaaccaatg tcgtataaca cgccatagtt acgaccataa tcaacagacc
     6961 ccatatcggc aaatgccaaa ccagcaaaac cgagacgcgt ccagctttgc ggggaaccgc
     7021 tggagtcacc atcttccgga cgattggcgt tgacctgata ctcccactgt ccaaaaccgg
     7081 ttagttgatc ggtaatttga gtctcgcctt taatacccat acggatataa gattgatcgc
     7141 catccgtact atgattactg gaaaaataat gcaggccgtc gaccttgcca tacaaatcca
     7201 gtttattgcc atccttgtta tagatttctg ctgcgttggc ggctccagcc atcatcacgg
     7261 ctgcggctac cgcagataac accactactt ttttcatttt atatgcctta tttgtcttat
     7321 ttttggactt tccgcaaaac ctgctcgcgg aactgtccgg gacaatatca ctaacaatta
     7381 ccgtgcgtta agtttcaaag tgtaatatta gcttgctatg tattagtgat gttaaaatgc
     7441 aagttaagca tggctacatc aatggtgtgc cctgttttct gctgtaataa caagggggtg
     7501 accagtagag aactggctta cggtcgggga tgccgaggtg agaatggcac tgaacactct
     7561 gctgacactt cattaagacg gaatcataat caagtcagtt gaggccacag cccttcttat
     7621 ttttgtgtat aatttgttac gtttacattt atttttaaat tagcgttatg aaaatatcag
     7681 tactactgaa atagcacttc ttcgcttcgc gtatttttac tatggttaat tatcacatag
     7741 cgcaaacggt catttgtgta tcactattca taagattaac tatttaccag tggtaataaa
     7801 cataaaagta agtcaaggga caacaacaat actgaaactc taaatgttga tattttgagt
     7861 catgccgtta caaacaaata cgatattctt aattgcacta ctcccttttc ggggtagttt
     7921 tatagaagga tgttttttat tgttcgagag ccatgctcct ttagtataaa ggtgaacgta
     7981 acaggaaaga taaagcgtct caaaaacaga ccatatgggt ataactatta tgcaaaaaac
     8041 gtcactattt ttttcagccg ccgcgataac gttaactctg atggcgtcat cggcatcagc
     8101 ggcaacgcca accgccgcac aaaatgaagc tacgtcgacc gttaaacaag aaattacaga
     8161 aagcattaac cgttaccttt attcaataga taaggcagac ccaacgttag gcaagcagct
     8221 tttttatgtt tcaccggaaa ccagttttat tcatccacgc ggtcacgaac gcggatggtc
     8281 gcagatcgct gaaaattttt atggcaccac tatgggtaaa acgttcagca aacgcacgtt
     8341 aaaactggac gctcccccgg ctattcatgt gtatggcaat gccgccgttg cagagttcga
     8401 ctggcatttt accgcggtac gccgtgataa tgggcagact caacacacga caggccgcga
     8461 aagccaggta tgggcgaaga taccaaacac aggatggcga atcgttcatg tccactactc
     8521 cggtccagcc aaaaccggcg ttggagaagg ctattaagct ttgcttttca ggttatggcg
     8581 cagatgaaca ttctgcgcca gttaagacga actcaggtca gttgatagcg cttatccggt
     8641 atccgttttg ccggaatatc cctttcatca ttcatttgca gtaaatcgat ttctatcgca
     8701 ttgcatatcg catccagcgg taaatcatta ttttcagtac cgaacggatc ttccaactct
     8761 tccgctaacg catccagcgc gataaacgta taagaaatca gcaccgaaat aaacggcgtc
     8821 atatagtgca gatcaaccac cagtgcaaat ggcaacataa tgcagaaaag ataaaccgta
     8881 cgatgcaaaa ttaacgtata ggcaaaaggc accggcgtgt tggcgatgcg ctcacagccg
     8941 gccaacactg acgacatatc atttaagcgg ttgttgaggc tatgaaataa aatatcggaa
     9001 agctttccgc tgcggcggcg aatcgccagc cactctccca tcagcaataa gatacggtta
     9061 gcgggggaat gggaagcgac aactttctgt aacgcctcct ggtcaagata gtttcccaga
     9121 acttgcgttt gaggctgtcg acgcaatgtc atacgcaaac agtgggcaaa agcgatttgt
     9181 aaccgaacaa aatcctcgat accgcgttca tcaggcaagg ttgttttcac ctctcgcagt
     9241 attgagcgtg aagcgatcat caactgcccc cacaaatgtc gggcttcgac gtaacgcgca
     9301 taacaggcat tattgcgaaa cccaagaaaa atggcgatag cgacgcccag tatgctaaac
     9361 ggcgcaaggg taaacttaat acccagcatt gtgtaccagg gcagcatgat aataacggcg
     9421 atagaaagaa gaaagttaag gagcagtcgt gaaaagattt tagataacac ggaaccatgc
     9481 cagacaaata tcaggcgaat ccagtgctgt tgtggtctaa cgatcatgat tatcttcagc
     9541 aggtgaaaaa gcactgtcat taaacgtgat ccagatcaag gttgcaagct tctggtgata
     9601 cacggattcc ctgctctgta gaacattttt ttgcatggtg ctgacaggcg ttggaaaaaa
     9661 acaaccaaat gtatgttgta actaaaaaga catttcagca catgagatat atgacggtca
     9721 acggctgcta tcagtggtat agggtgattt atcggggaaa gcgtcagcaa cgacgcgcta
     9781 ccctaccgct gattcatttg tatgaccagc cagtaatgaa taacgctgac aatatactgt
     9841 tgctgcgctt tactcagcgg ttctccctga ggaatctggt gccacttcgc caggcacccg
     9901 cgacagcagg ttgccgtcgc atgttgcgcg ataaataccg gatggccccg catcggcgtt
     9961 tgcttaccat cattcgccgg gtgagctggc accagtcgct gggcgataaa atcggcggcg
    10021 tgtttatcaa tcacctccgc gcctttatcc cagcaatatt gtctttcttt tatcccgaga
    10081 cgaaagcgcg aacgaaatgt cgatcgcgcc aggcgggcaa agagcggttc aagcgcattc
    10141 atcagtatac caaacgtcct aacgtttgtg ttaattgttc aagcgcggcg atacctgcca
    10201 gagagtttcc cgcaggatcc agctccggac tccagacggc aatcgccatt tcatgcggca
    10261 caatggcgac aataccgccg cccacgccgg atttagcggg caatcccacc cgccaggcaa
    10321 actcgccggc attctgatac ataccgctgg tcgccattag cgcattaatc tgccgggcct
    10381 gcatgggggt aactaccggc tcgtcgagat gaaacgcctc gccctgattc gccagaaaga
    10441 caaacgtcct cgccagttcc atgcagctca ttttcaacgc acagtagtgg aagtaatttt
    10501 gcaacacggt aggcacatca tgatgaaaat taccgaatga tttcatcagc caggcaatag
    10561 cggcgttacg ggcggaatgc tcaaattcag agcgcgcgac cgtagcgtca tatgtaatat
    10621 ccgatacgcc gcaaagcgcg cgcgcaactt ccagcatccg ctgacgcggc gcgctaagcc
    10681 gcccttgcaa catgtcgcat accaccagcg cgcccgcatt aataaatgga ttacgcggga
    10741 tgccttgttc catctctaac tgaaccaacg aattgaacgg cgagccggaa ggatcttttc
    10801 cgacacgctg ccagatctcc tcttccggat aatgacgcat cgccatcacc agactgagca
    10861 ctttcgaaat agactgaata gagaagcgtt cgtgcgcatc gcccgcctga taatgctgcc
    10921 cgtccacggt acaaatcgct attcccagct ttgaaccctc gacggacgct aatgccggaa
    10981 tatagtcagc tactttgccc tggccaatga gggggcgaac gcgctgtaaa atcgtttcta
    11041 aaattgcatt atccatggcc ctggccacaa catgctcctt gctcgcaggt ctgaaaaggc
    11101 ctgcgagtat agcagagggc gccacgcgac gtcagggcga ttagacgcgg ttcttccaga
    11161 cggtctgcac attacaaaat tcgtgtaaac caaagtgcga aagctcgcga ccgaagccgc
    11221 ttttcttcac cccgccgaat gccacacgcg catcgctggc gctgtaccca ttaatgaata
    11281 ccccaccgca ctcaagacgc gccgccatct ccgcggccag cgtatcgtcg gcggtaaaga
    11341 tcgtcgccga caggccaaac tcactgtcat tcgccagcgc gagggcgtgc tccgcatctt
    11401 ttgcaacggt aatggcggca acaggcccaa aaagctcctg acgaaatgcc gtcatgtcag
    11461 gagtgacatc cgccagaacg gtcgcggcat aatagttgcc ctccccggcg attttctcgc
    11521 cgcccaacag tagccgtgcg ccttcggcga cggaagcctg cacctgttga tggagttcat
    11581 cacgcaaatc aaagcgcgcc atcggcccca gatcattctc ttcaaccaga ggatccccca
    11641 tctttaatgc tgcggcagcc gccacaaaac gatcgttaaa cgcctgcgca atgccctctt
    11701 cgacaataaa acgtttggcg gcggcgcaga cttgtccggt gttttgatag cgtccggcaa
    11761 ccgcggcttt taccgccagc tcgagatcgg catcattgag tacaataaac ggatccgagc
    11821 cacccagttc cagtacgcac tttttcagcg ccgccccagc ctgagcgcca atcgccgcgc
    11881 cggcgcgcac gctaccggtc accgtcaccg ccgcgattcg cggatcgtta atcatctgac
    11941 tcacgccctc attattggca ttcacccatc catagacgcc agcgggagta ccggcttccg
    12001 tcaagattcg ggctatcatc tgcgcgcaac ccgtgacatt gggcgcatgt tttaacaagt
    12061 agctattccc cgccaacagt atcggcactg ccccgcgtaa cacctgccat aaaggaaaat
    12121 tccacggcat tatcgccaga atgacgccca gcggacggta ttcaatcacc gcctgctgat
    12181 tttctaccag cgtaggctca ggattcagca ttgccggacc atgttccgca taccagtcgc
    12241 ataacgcagc ggatttcgtc acttccgcac gcgcctgctt tataggctta cccatttcac
    12301 gcgtaataca ttgcgccatc tcttctgcat gagcgcgaag cgcctgacca atatcgcgta
    12361 atgtttgcgc ccgttgcgct accgatgtca ttttccactt tttgaaaccg ctcgccgcca
    12421 gactcagcgc atgttcaatc tcttgcgcgt tagcccaggg cattgccgcc agcgtctggc
    12481 cggtcgcagg attaacggat aacgcctgtg ttgcagtcat catggtcatg ttctttctct
    12541 cgttatcagg ggagttgtac catcatgacg ccctttaccc tttctgaaaa atgaataata
    12601 ttaaccagac tattcacgaa ttgagaaaac catggacctg acgcaactgg aaatgtttaa
    12661 cgctgtcgct ctgacgggca gcattacgca ggcggcggca aaagtgcacc gcgttccgtc
    12721 caatctgacc acgcgtatcc gccagcttga agccgacctg ggcgtctctc tgtttattcg
    12781 cgaaaaccag cgactcaggc tgtcaccagc cgggcataac tttttacgtt acagccagca
    12841 gatcctggcg ctggttgatg aagcccgtat ggtggttgcc ggagaggaac cgcaaggact
    12901 gttttcactc ggcgcgttag aaagtactgc cgccgtacgt atccccgcgc tgctggcggg
    12961 ttataaccag cgttacccta aaattcagtt cgcgttaacg accggtcctt ccggcgccat
    13021 gctggatggc gtgctcgaag gaaagctgaa cgccgccttt attgatggcc cgctaatgca
    13081 tccggggctg gaaggtatac cggcttacca ggaagagatg atgatcgtcg cgccacacgg
    13141 ccattccgtc gtttcgcggg ccagcgaggt gaatggttat aacatctatg cttttcgcgc
    13201 caactgttct taccgacggc atttcgaaag ctggtttcat gccgatggcg cgacccccgg
    13261 tacgattcac gaaatggagt catatcatgg aatgttggcg tgcgtaattg ccggcgcagg
    13321 tattgcgctg atgccagcaa gtatgctcaa cagtatgcca ggacatcatc aggtggaagc
    13381 ctggccgttg gcggagaagt ggcgctggct tagcacctgg ctaatgtggc gacgcggggc
    13441 gatgacgcgt caacttgagg cctttatcga gttacttaac gcccaactgg cgagcgccga
    13501 ctgaagacga aacggcctgc gaagtaaatg agaagcaggt cacaaaatga ttgtcttttc
    13561 gccagtaaac gttttaagat cgcggtctca ccttctcgca actaacccga aatattttta
    13621 tgacaatcaa tccagtttcc cgcaaggtcg cgtggctacg ggtagttacg cttgctattg
    13681 ccgcttttat tttcaatacc acagaatttg tgccggttgg tttgctatca gacattgctg
    13741 aaagctttca tatgcaaacc gcgcaggtcg gcatcatgct aaccatttac gcctgggtag
    13801 ttgccgttat gtcgctgcct tttatgcttc ttaccagtca aatggagcgc cgtaagctac
    13861 tcatttgtct gtttgttttg tttattgcca gccatgtgct ctcctttctg gcatggaact
    13921 ttaccgtgct ggtcattagc cgtattggta tcgctttcgc ccacgctatt ttctggtcga
    13981 taaccgcctc gctggcgatc cgcctggccc ctgccgggaa acgcgcgcag gcattaagtc
    14041 tgatagcgac cggcaccgcg ttggccatgg tgcttgggct gccgataggt cgcgttgttg
    14101 gtcagtattt tggctggcgc accacctttt ttgccatcgg catgggcgca ttaattacgc
    14161 tgctatgtct gattaagctt ctaccgaaat tgccgagcga gcattccggc tcactaaaaa
    14221 gtttaccttt gctattccgg cgcccggcgc taatgagcct ctatgtacta accgtcgttg
    14281 tggtgactgc gcattacaca gcttatagct atattgaacc gttcgttcag aatgtcgccg
    14341 ggctcagtgc gaattttgct accgtcctgt tactgatcct cggcggcgcc gggatcatcg
    14401 gcagccttgt gtttggtaaa ctgggtaatc gtcatgcctc gtcgctcgtc agtatcgcta
    14461 ttgccctgct ggttgtctgt ctgcttctgc tgctgcctgc ggcggatagc gaagcgcatc
    14521 tggccatact gagcattttc tggggcatcg cgattatggt gatagggctt ggtatgcagg
    14581 tgaaagtact ggcgctggcc ccggacgcga ccgatgtcgc aatggcgcta ttttcaggca
    14641 tctttaatat tggtattggc gctggcgcgc tggtaggcaa tcaggtgagt ttgcactggt
    14701 caatgtcggc catcggctat attggcgcca tacccgcctg tgccgcgctg gtatgggctg
    14761 tgctcatatt ccgcaaatgg ccagtgacgc tggaagaaca accgcattaa gacattcgtc
    14821 tgccgggaac aggtttccgg cagacgacaa tgcgccttag tggtacgttt taataatttc
    14881 caacacgccg ttgataataa attgcacgcc catacacacc agcaggaatc ccattaagcg
    14941 ggagatcgct tcaatccccc ctttacccac cagccgcata atagcgccag aactgcgtaa
    15001 gcatccccac aggatcaccg ccacggcaag aaaaataatc ggcggcgcga ccataatgac
    15061 ccagtcggga aactcgccgc catgacgcac cgtggaagcg gaactgatga tcattgcgat
    15121 ggtccccggt cctgcggtgc ttggcatagc cagtggaaca aacgcaatat tggccgtcgg
    15181 ttcgtctgcc agctcctccg atttgctttt cgcttccggc gactcatgcg ccttctgctg
    15241 cgggaaaagc attctgaagc cgataaacgc cacgattaac cccccggcga tccgtagccc
    15301 tggaatcgaa ataccgaagg tgttcataac taactgcccg gcatagtacg ccaccatcat
    15361 aatagcgaag acataaaccg aagccatata ggactgccgg ttgcgttccg cactattcat
    15421 attgcccgca aggccaagaa acagcgccac ggtggttagc ggattggcta acgggagcag
    15481 tacgaccagc cccaatccaa tcgctttaaa caaatccatc ataatactat ctcttaccca
    15541 tcagcgtttc atgaaccgga agtataaagt gaaattgccc aggcgcgcca tttcgccagt
    15601 gtgcaagtca atatttttta caacctataa cctgtaatta tcaattagtt acaagttatc
    15661 acagcacaat accccggacg ccttttagca aatcgtggca tcggccaatt catttagttg
    15721 acttatactt gcctgggcaa tagtatctga caaaattaat tacttgccgg ggcaaccatt
    15781 ttgaaaagca ccagtgatct gttcaatgaa atcattccgc tgggtcgctt gatctacatg
    15841 gtaaatcaaa aaaaagatcg cctgttaaat aactatttat ccccgctgga tatcaccgca
    15901 acacagttta aagtgctgtg ctcgatacgc tgcgcgggat gtattacccc ggttgaactt
    15961 aaaaaagtgc tgtctgtcga tctcggcgca ttgacgcgga tgctcgaccg cctgctgtgc
    16021 aaaggctgga tcgaaagact gccgaatcct aatgacaaac gcggcgtact ggtgaagcta
    16081 acgccggacg gcgcggcaat ttgtgagcaa tgtcatcaac gaccagggca agacctgcat
    16141 caggaattaa caaaaaactt aacggcggac gaagtggcaa cgcttgagta tttgctcaag
    16201 aaaattctgc cgtagacaaa aaagaggtat gacgatgtcc agacgcaaca ctgacgctat
    16261 tactattcat agcattttgg actggatcga ggataacctg gagtcgccgc tctcactgga
    16321 aaaagtgtct gagcgttcag gatattccaa atggcacctg caacggatgt ttaaaaaaga
    16381 gaccggtcat tcattaggtc aatacatccg cagccgtaag atgacggaaa tcgcgcaaaa
    16441 attaaaagag agcaacgagc ccattctcta tctggcggaa cgctatggct ttgagtcaca
    16501 gcaaacattg acccggacgt tcaaaaacta ttttgatgtg ccgccacaca aataccggat
    16561 caccaatatg catggcgaat cacggtatat gctgccgctg aaccatggca actactagtt
    16621 tgtttatgcg ccacgcgaag agcaccatga aaatgctgtt tcccgccctg ccgggtctgt
    16681 tacttatcgc ctccggatat ggcattgcag aacaaacttt gttacctgtg gcgcaaaata
    16741 gccgcgatgt gatgcttctg ccctgtgtgg gcgatccgcc aaatgacctt caccccgtga
    16801 gcgtgaacag cgataagtca gatgaattag gcgtgcccta ttataacgac caacaccttt
    16861 aacctctttg ccccgttttg cggggcattt ttttagtacc gtctggctat gacaagtccg
    16921 ccgctattac cccgcggcat ggtctgaaat tagcgtttgt cttcttagta acataatgcc
    16981 tcatcccctg acgcgcgcag tacggcgcac acgaaatcca aacacattga tatagagtcc
    17041 agccataatc agtactgcgc ccgcaagctg catcccggtc aacgtttccc cgagtaacac
    17101 cgcggcgctc gccagcccga ctaccggcac cagcaatgat aacggcgcca cgcgccaggt
    17161 ctcatagcgc cccagtaacg tgccccagat gccgtagcca agtatagtgg cgacaaaagc
    17221 cagataaagc agcgacaata tcgtcgtcat atcgatggta ataaggcttt gcgtaatgtg
    17281 atccgccccc tccagtagca gcgatgacag caggaacggc aggatcggga tcagcgcgct
    17341 ccagaccacc agcgacatca ccgccgggcg cggactatgt tgcataattt ttttattaaa
    17401 gatattgccg caggcccagc taaatgccgc cgccagtgtc agcataaatc ccgacatcgc
    17461 tatatgctgt ccgttgagac tggcttcaat caataccagt acacctataa tcgccagggc
    17521 gatccccgct aactgcttac gttgtaaccg ctcactaaaa acaaacgccc ccaatgccat
    17581 ggtaaaaaag gcctgcgcct gtaataccaa cgacgccagt cctgcgggca taccaaactt
    17641 tatcgcgcaa aagagaaagg cgaactgccc aaagcttatc gtcagcccat agcccagcaa
    17701 cagcgtaagc gggactttag gccgggcgac aaagaaaatt gccggaaacg ccaccagtaa
    17761 aaaccttaat cctgccagca ataatggcgg catatggtgc aggcctactt tgatgacaac
    17821 aaaattgagc ccccatacga caaccaccag taacgccaaa aaaccgtctt tacgcgacat
    17881 catcggcccc tgtcattatt aaaattttgt aaaaaggtaa gttatcggaa atcagtgcgc
    17941 cataacagga cttttctttt taccgtgagc atggcattga acaacacacg atgggcaaaa
    18001 tcctgcgtta tggtatgtta agactacgct atagcgtaca gacatcatgc ttttgcgggc
    18061 acggtagatt aaaacgtccc gatacgtaac ctccatttca ggcaggaaaa atgaatccag
    18121 gattgagacg ttcgacgttg gctctactcg cctcatcgct gttattgaca attggacgcg
    18181 gcgccacgct cccctttatg accatctatc ttaaccgtca gtacggttta ggcgtggatc
    18241 tgattggcta cgcgctgacc agcgcgttaa cgatcggcgt catctttagt cttggctttg
    18301 ggattctggc ggacaagttt gataaaaagc gctacatgtt actcgcgatt atcgccttcg
    18361 cctgcggatt tatcgccatc ccaatggtgc ataatgtcgt actggttgtc ctgctttttg
    18421 cgcttattaa ctgcgcctat tcggtttttt ctaccgtcct gaaggcctgg ttcgccgata
    18481 acctcaccgc gacaacaaaa acacggattt tttcgctcaa ctataccgta ctcaatatcg
    18541 gctggacggt tggcccgccg ctcggcacgc tgctggtgat gcaaagcatc aatttaccct
    18601 tctggcttgc cgctatctgt tccgcatttc cgctggtctt tattcaggta tgggtgacac
    18661 gttcggttgc cgccagcgag gggaaaaatg ccgctatctg gtctccctcc gttctgctgc
    18721 gcgacaaagc attattgtgg tttacgcttt cggcatttct ggcctccttt gtgggggttg
    18781 cctttgcgtc ctgtatttca cagtacgtta tggtcgttgc cgatagcggc ttcgcggaaa
    18841 aagtggtagc cgtcgtcctg ccggttaatg cggttattgt ggtcagtttg caatacgccg
    18901 tgggccgtcg acttaccgcc gtcaatattc gaccaatgat gacgaccggc accgtctttt
    18961 ttatcgccgg gctcatcgga tttatttttt caggcgacaa tctgtttttt tgggggcttt
    19021 cagcggcagt attcacgatt ggcgaaatta tttatgcccc cggcgaatat atgttaattg
    19081 acaacattgc gcctgccggg atgaaagcca gctatttttc agcgcaatcg ctgggctggc
    19141 tgggtgcggc ggtaaacccg ctggccagcg gcgtcatcct gacgacgctt cccgcctggt
    19201 cgcttttcgt tgtcctgata atcgccattg tgttcgcctg ggcactgatg ttaaaaggaa
    19261 tgcggattac ccctacgcaa caggctatca cctgttaatt atctgcagcc agtcatgtgc
    19321 gctgtttctg gcgcactggg ttaaccctat atattgcagg ctaattatct gctgtaactg
    19381 cggtaattca ggaatattcc tgggcgctga cgaaaatatt ctaatgcttt acccttccag
    19441 taaaataaat acgcaattca gactttgctt aagtataaat tagtactata gtttgtacga
    19501 ggttttttaa aaaagaggat gcacgctaaa ataaggagaa acgagatgtt aggtagtatt
    19561 aaccttttta tcgttgtatt aggaattatt ttattttccg gatttctggc cgcctggttc
    19621 agtcacaaat gggatgatta atgaacggag ataatccctc gcagagccgg ccccttgctg
    19681 catcgttgcg caaggggccg cttttgtctg gatggcaggc aaaaaaaaac cgccggttca
    19741 ccagcggtaa atgcttgcat ggatagattt gtgttttgct tatacgctac cgggcaaatt
    19801 cttgcgagga taacggatcg ctaacgactg tagcaccgtc aatatcaatg aagcttaaac
    19861 gatacgcaac cagacctgaa taagacatta tgggaccttt tgtccccagg gcgcttttac
    19921 aagacccata gtatcaggcc agccgcatgc cccgtatggc tgacctggat attgccggtt
    19981 agcgcgcgtt atttttgcaa tcggttcacg cggacaagcg gttccttcgc tttcttgtcc
    20041 agatttgatc cggctgaact tcccgcccat caaatacggc ggaaggaatt atcacgttaa
    20101 tctcgccgga cttatcacga aatacatagc gatcgtcgcc tttatgatca ataaggttgc
    20161 cgcgcagcga aacggtcgcg ccatcatgca gggtttttgc ctgttcgatg gtcatttttt
    20221 ctgcatcatc cgtaccgcga taaccatcct caatagcatg aggcggcggc ggtgccacgt
    20281 ctttttttaa tcccccctga tcttccgcta gcgcgtaagg cattatcaga aaacttaaaa
    20341 atgcagccac ctgtagtttc atgctctctc cttaataacg tctatttgac gtattaagtc
    20401 tggccgctat ttttagtttt tacaaacatg aatttacccg cagaatatta agcaataaaa
    20461 tcaacccatc cggattaata tgcaaccgat atcagcgcca gtgagcgcga aagcgtaacg
    20521 gcgtaatagt taacttgcca catagctgaa gtcatatgca tcaacgtctg gatagcaatt
    20581 cagaataatc ggctttattt tttgaggata atggccttcc acataatcaa tgacagtcat
    20641 cgccgtaaga aagtaagcaa gttatgcaac agcgggtttg ttggtaactg gataaaataa
    20701 tcattcactg acaatgtcat aaaataaata tgccatactt gagaagaacg aacagatttc
    20761 atttgtctct gtaacggaaa aataaacgat gagattagaa cagcacgata ttgtcaccct
    20821 tgatgaagcc gaatccgtcg atagcctgac aaaaaaactt ggtgatttac tggttaacca
    20881 gaaactccgt ctgaccagtg cagaatcctg ccctggcggg aaactggcgt cagcattgtg
    20941 cgcagcagaa gatacgccct cattttacgg tgtggggtat gtcaccttta ctgatgaagc
    21001 caaagcaaaa atcttacgcg tacaacgcca cagtcttgcc gaacataccg ccgtcagcga
    21061 agcggttgtt actgaaatgg cacagggcgc taaggatcag gctgaggtca atatcagcat
    21121 agcgatcagc ggctatggcg gtccggaagg cggcgaagat ggcacgccgg cgggcacagt
    21181 ttggtttgcc tggaatatta acaatacaac ttttacaagc cgacaacatt tcaacggaga
    21241 ttgtcaggaa gtattggaaa aatgcgtacg cttcgccctc gctgaattgc tttttctgtt
    21301 aacgaagaaa gcataaacaa taatttcatc tgaccggtca gaataactcc cggtcagaat
    21361 aaaaaaatgc gagcctatgg cccgcatcgt atgtgcaata tttcagaata tatttatgaa
    21421 atatcagcag taaaattaat tgccggattt ccgtccgcca ctgtggctat tctggccacc
    21481 ttttttaccc gcttcagatg cacgttgtgg gtcgttttta aagttcccac cgctatgctg
    21541 gccgccttta cgacctgctt ctgaggcttt ctctttatct tctgcaaaat taccggaacc
    21601 gccgcgatgt tctgccataa tataatcctc atgatgatgt tgcgttttaa atatgatatg
    21661 tcttctcata tcatgtgata cagttctaaa tctagtcgcc ctgtgcgcag tgttaaattc
    21721 atttctgcat tatttacata ataccaccac atggcggaaa atatattttt tgaaaacatc
    21781 aacagcgaag cggtaataaa tctttggcaa tcaagccacc acgggaaaat aagtagaaaa
    21841 atccgaatgc acgccctcgt tatattcaga caacttaacc ccataaattt aactggctgt
    21901 catcagaagt gcaggattca ttttcaggcg gttgttcgac agtgccgaac aaccgtatca
    21961 gcttagtgat cgagcccacg atattgcaat atggtgtcaa tatgcggttc atgtccacgc
    22021 caggctgaat aaagcgtttc taaatcagta ctattccccc gggaaaggat agcatcacga
    22081 aaacgctgcc cgttttcacg cgtcaggccg ccctgctcta caaaccattg ataaccgtca
    22141 tccgctaaca tttgcgtcca caggtaggcg tagtatcccg ctgcgtagcc gccgccgaag
    22201 atatgggcaa aataactgct gcgatagcgg ggcggcactg ccggtaaatc aagatgctcg
    22261 gcggccagcg cctgctgctc gaactcagcg acagactgct ctgctacgct ctcctccagc
    22321 atatgccagc gcatatccag caatgcggcg ccgaacaatt cagtcatatc gtaaccttta
    22381 ttaaataaac tcgccttgcg cattctttcc tgtaaatcag caggcatttt ttcaccgctg
    22441 tcgacatgac gcgcgtagcg ttcgaacaca cgtggatggc tcgcccaatg ctcattaatc
    22501 tgggagggaa actcgacaaa gtcgcggggc gtattggtac ctgaaagcgt ggcatagcgc
    22561 tgaacggcaa acaaaccatg taacgtatga ccaaactcat ggaagagcgt aataacgtcg
    22621 tcccaaagca gcaatgcagg ctgcccatca accggtttct gatagttaca tacattgtat
    22681 ataacgggcc gggtttcatt gagtgtggat tgctcgacaa aattccccat ccacgcgccg
    22741 ccgcttttcg agtcccgcgc gaagaagtcg ccataaaata acgccatgcc gacaccatcg
    22801 gagtcgaaaa tctcccacac ccgaacatca gggtggtaca ccggaatgtc aaaacgctcg
    22861 acgaaggtga tgccgaatag ctggttggcg gtccagaaaa cctcctcttg caacaccgta
    22921 tttaaggcaa aatagggctt cagttgcgct tcatctaacg catatttttc ccgccgtacc
    22981 tgttcggcat agaacatcca gtcccaggcc tgaacggtgt agccgccctg ctcaccatca
    23041 atgacgttct gaatttccgc ctgttcattg agtacccgct gacgcgctgg cggcacaatg
    23101 ccacgcataa agctcagtgc ggcttgcggc gttttcgcca tctgatcggc cattttccat
    23161 gcggcataat tggggaaacc cagcagtttt gcctgacagc ggcgaatctc taccagacgc
    23221 tgaacgatag cgcgggtatc gtgggcatct cctttttccg cccgagtcca tgacgctgcg
    23281 aataaatttt cgcgagtctg gcgatcgcgc agcgtagcaa gcgcaggctg ttgcgtcgta
    23341 ttaaggagcg gaatgaacca gcgctcctcc aggccttttt cacgcgccgc ttcagcagcg
    23401 acggtcattt cttccgggct taatccttcc agacaatgcg cgtcatctac cgccagcccg
    23461 cccgctttac ttgccgccag cagacgctga ttaaactgac tcattaaggt cgcggattca
    23521 gtattcaata ctttcagtcg cgctttatcc tcttcggcaa gctgcgcgcc tgccaacaca
    23581 aaacgctgat ggataacatc gaccaaccgt agcgactcat catccagccc cagtgagtga
    23641 cgctgttgcc agacggcatc cacgcgagcg aataacgcgc tattcagata aatatcgttg
    23701 gagagcgccg ccagctcggc agaaaaggcc tcatccaacc gctggagttc atcgttagtg
    23761 tgcgcagccg tcatcgcgaa aaaaacgctg gtgacgcgtg acagaagcgc cccgctttgc
    23821 tccagcgcca gaagcgtatt cgtaaaatca ggggccgccg gatgattgac gatggcctcg
    23881 atttccacgc gtttttgccg cacgccctca tcaaaagcag gacgataatg gcaatctttg
    23941 atccgatcaa aacgcggtgc ctgataaggc aacatactct ggtctaacaa aggattcgtc
    24001 gacatttttc actcctgaaa ataggttgat cataagagta agcttccccc tatgctgacc
    24061 gcaaccgtgt taaccaggat taccctttca taaacgccgc gtgctatggt aatacaacac
    24121 aaaaagcgtt gaggaactgt gtgatgatcg ttttagtaac tggagcaacc gcagggtttg
    24181 gcgagtgcat tgcacgccgt tttgttgaga atggacataa agtcattgcc acgggacgtc
    24241 gtcatgaacg cctgcaagcg ttaaaagatg agcttggcga gaacgtattg accgcccaac
    24301 tggacgtgcg caaccgcgcg gccatcgaag agatgatggc ctctctgcct gcgcagtggc
    24361 gcgatattga tgtgctggtc aataacgccg gtctggcgct gggtcttgaa ccggcgcata
    24421 aagccagcgt agaagactgg gaaactatga tcgatactaa taataaaggc ttaatttata
    24481 tgacccgcgc cgtgctgcca ggaatggtcg aacgtaatcg cggtcatatc attaacatcg
    24541 gttcaaccgc cggcagttgg ccttatgctg gtggcaacgt ctatggcgcg acgaaagcct
    24601 ttgtgcgcca gtttagcctg aatttgcgca cggatttaca cggcacggcg gttcgcgtga
    24661 ccgacattga accgggtctg gttggcggca ccgagttttc cagcgtccgt ttcaaaggcg
    24721 acgatgagaa agcgggtaaa acctacgaaa ataccaccgc gctcacgcca gaagacatta
    24781 ccgaagcggt atggtgggtg gccacactcc ccgcgcatgt gaatattaat accgttgaaa
    24841 tgatgcctgt tacccaatcc ttcgcagggc tcagcgtcca ccgtagctaa ggggttatac
    24901 ccggtctgcg ggccgggtaa tccctggcaa acgtatctgc aaccagaaac atgatcggta
    24961 tagaccgcca cggaaaagtg gtagagtatc cgggtcaacc gcctaaaaag taagaatgaa
    25021 tgaccgtcga aacgcagctt aaccctacac agcctgtcaa ccagcaaatt taccgtattc
    25081 ttcggcgtga tatcgtgcat tgtcttatcc cgcctggcac gccgctatca gaaaaagagg
    25141 tctcaacccg ttttaacgtt tcgcgtcagc cggtgcgcga ggcttttata aagctggcgg
    25201 aaaatgggtt gattcagatc cgccctcagc gcggtagtta tgtgaataag atttcgcttt
    25261 ctcaggtaca gaatggctgc tttgttcggc aggcgatcga atgcgcggtg gtccgccgtg
    25321 cggcggcgat gatcaccgac aaccagtgct atcaactggc gcaaaacctg cacctgcaac
    25381 atattgccat cgagcgcaaa cagattgatg attttttcca gcttgatgac gatttccacc
    25441 aaaaactggc gcagatcgcc gattgccagt tagcgtggga taccattgaa aatatcaaag
    25501 cgacaattga ccgggttcgc tatatgagtc tggatcatgt ttctccgccg gagatgttgc
    25561 tgcgccagca ccatgatatt ttctccgcgc tggaaaatcg tgacggcaat gcggttgaga
    25621 gcgcaatgac ccagcatttg caggaaatta gcgaatccgt tcagcttatc cgtcaggaaa
    25681 acagcggctg gtttagcgaa gagtaacccc ctttaacgtc ggggtgagac gccttctccg
    25741 ctttctcgcc ctgcacattc ccgcctaaaa agccgtgagc ttgatcaaaa acaaaaaaaa
    25801 tccgcaacga taagcgtatt tatatgtcgc ccgtcatgcg gggaaacctg cgggctttgg
    25861 cagtaagttt gaaaggagaa aacaccatga tgacatacga tcgtaaccgt aacgcaatca
    25921 ccaccggtag ccgggtcatg ataagcggca cgggccatac cgggattatc aaagccattg
    25981 agagcgaagg tctggatgca ggtcaaattc gccgcggcaa aacggtgatt gtcgaaggtt
    26041 gtgaaggtaa attcgcgcca gtcgaactga ttcgtcttgg catgaactga taccactggc
    26101 cgctaagaac cgctccggcc ttcccggtag cataatgcta ccgggtctct gttacgctat
    26161 ttcaagcgct cggcatattt cgccacgctc gctttcgcgc catatgtcag taaactgtca
    26221 taggcttctt gcactttttg cgtaaaccgc gccgcctgcg gcaaatcgtt gccgaaaatt
    26281 tcagccattc ccagcagcgc cttaacacga ctggcgcctt cttcactgtt tgccacggcg
    26341 cgctgaataa ccggcaatag cggatcgctg acgtcgatcg ccttaccctg ctcatccacg
    26401 ccgccaacgt aacgcatcca ccccgccacg cccagcgcca gcaaatcaaa atcgctatga
    26461 ttagcaagat gccagcgaac ggagtccagc atacgctgcg gaagtttctg gctgccatcc
    26521 atcgcaatct gccaggtatg atgacgcagc gccggattac ggtaacgcgc aatcaactga
    26581 tcggcataac gctgtaaatc taccccctgg actttcagcg ttggcgcctg ctcgcgtaac
    26641 attaacgcct gcgcggtcag acgatagttg tcgtcatcca tacagtcatt aatatgctga
    26701 tagccggcaa gataccccag ataagccagg aatgaatgac tgccgttaag cattcgcagt
    26761 ttcatctctt caaacggaac cacgtcggcg accaacgtcg cgcccgcgtt ttcccactgc
    26821 ggacgccccg ccacaaacgt atcttctatc acccactgac gaaacggttc acaggcaacg
    26881 cccgccggat cgcgcacgcc ggtcagttgt tcgattttat ccagcgtctc cggcgtgacc
    26941 gcagggacaa tccgatcaac catggttgac ggaaatgtca cgttttgctc gatccatatc
    27001 gccagttccg catccacctc ccgggcgtaa gccgtcacaa cctgacgcgt cacatgccca
    27061 ttttccggca tgttgtctca ggacatcacg gtaaatgccg gtaagcctgc ggctttacga
    27121 cgcgctaacg cttcgacaat aatacccggt gccgttagcg gttgatgcgg attttgcagg
    27181 tcggcggcaa tcatgggatg ttccagcaga agttgacccg tggctggcga atgacaatac
    27241 cctttctcgg taatggtcag agacacaatc gctatttgcg gttcgcacat cgccgccagc
    27301 acacgttcca gaccatcaac ctgaacatgc aacgccgctt tgacgacgcc caccacacgc
    27361 gccgtccagg catccgccga catctccgcc acggtataga ggttatcctg ctgctttaga
    27421 tcggcaatct gctgttcgcc gccaataaga ttaacctcat aatagcccca gtcgctatgc
    27481 tgctccgcag ccagaatatc tgtataaacc ccctgatgcg cgcgatgaaa cgcgccaaaa
    27541 ccgagatgga ccatccgcgc cgccagcgcc gcgcgatcgt aatcaggaag cgtcgccttt
    27601 gccgataaaa gcctgttttg cattttataa cctctatatt ctgaaagcgg aacagtcgca
    27661 gagtaacgcc tgccctggtg catttggatt tacgctaatt aaacaaaagt gaccggacag
    27721 catggccgaa accgcattaa cgttccggcc ataccgtcga cacgatttaa ctcgtctggg
    27781 ttgcggagtg gcgtaacttc tctgccgctg tcgcttccgc cgcatcctca ggcaaactca
    27841 ggtcgcgatc tctgacctcc ggcatcaaca gcgcagaaat cagaccaata cacgagtaga
    27901 gcaccagcat aattaagatg ggcagccagg aatcggtcat gttacaaaag atccctgcga
    27961 ggacggggcc aaagccaacc gccaccaggc ctcctgcctc ttttgaaatc gccatccggg
    28021 tgaagcgatt acgcgatccg aaaatttccg ccatggtgat gttttccagc gcaaataatc
    28081 ccagcacggc aaagttatga ataacaatga gcgccgccat aattacgcca gggctatacg
    28141 ttttatctac cacaatagac aacatcggcc aggcgagaat aatcgcggag atattcaata
    28201 ttatatacgg tagccgacga ccgtatttat cggacaacca ccccaagagt gggatagtga
    28261 taaaaccaat tacggaactt atcattaacg catcggttgg gatagatttg ttaaataata
    28321 acgtctgaac taaatatccg gcaaggaaag tttgaataag cccggaattc cccgcctgcc
    28381 caaaacgtaa accggtggcc agccagaaag atttgctggt aaacatcgcg cccaatgtat
    28441 tttctgacgc aggcgttaac gctggcgatt tttcgccttc gcttactttt tcgaataccg
    28501 gactttcttt cagattcatt cgcagccaga tcgcgaatat cataacaacg acgctcgcca
    28561 ggaaaggaat acgccatccc caggcgatca gttgttcgcg ttcaagcgca aagaacatca
    28621 ccgcccagat cgccgtcgcg ctcaacgtac cgcaattggt gcccatcgcg accagcgagg
    28681 aaatgatgcc acgctttcct ttcggcgcat actcggccag catggtaccc gcgccggaaa
    28741 tttccgcccc ggcgcccagc ccctgtataa ttcgcaatgt taccagtaat actggcgcaa
    28801 aaatgccgat ttgcgcatac gtcggcagta cgccaatcag cgtggtgcag atccccatca
    28861 tggtgatagt aataaacaat actttttttc gtccgatgcg gtcgcccatt ttaccaaaaa
    28921 caaaggcgcc gataattctg gctatataac ctgcaccata ggtgcccatt gccagaataa
    28981 gcgccatcgc ggcagactgt tccgggaaaa atatctcatg gaagaccaga gccgcgccta
    29041 gtgaatataa ctgaaaatcc ataaattcaa gcgcggtgcc taaccagcca gatacggcag
    29101 cgcgcactaa atcctgagtc gatcgttcat gctttatttg tgtcatatag gcaatctcta
    29161 agaggtaaga tgcgtaccac ttactcgcaa gtatttatat tatttcgcaa acgtgagtaa
    29221 gactttgcag cattgacgct ggtctttctc gaaaagctca atcgcgtcgg tgacatgttg
    29281 ataatcaaat gtatgcgtta tcagcttatc cggatcaata agccctttat tcagccagtc
    29341 aatcacgacc gggaatttat tggcattaag acgcgatgaa taaatagcca gctcttttcc
    29401 ggtaataccc tgctgtacaa tctcacacgg gtcgctggaa aatcccatca ggacaatgcg
    29461 tgccgcaggc gattcttcaa tgcgatcaac gactatgacc gttttaacct gataaacccc
    29521 cttcaacgcc tgtacggtcg tcagtcccat cgggcctgcg ccatagataa gcgccacgtc
    29581 ctgctcggtc ggattcacct gccccgtcac atttgccgca atggtaaacg gctcaaccat
    29641 gacggcatga tggtctgcga tgttgtccgg tatgcgatga gcattacggg ccggcgccac
    29701 cgcatactcg ctgaaaccgc cgtcacgatg cacgcccagc accaccagcg aggtacacac
    29761 attgggttta ccgactgaac aagggtaaca atgcccgcaa ctgatcaccg gatcgacgga
    29821 tacccgttct cctatccggt cgcgattgac gttgtcgcct accgcgtcga tgacaccgaa
    29881 aaattcatgg cctatgacac ggggatattt tgcaaaggga ttatgtcccc gataaatatg
    29941 gctgtcggaa ccgcagatac ccgccagttt cactttaata cgaacttcgc cagatgctgg
    30001 ctgcagaagc gcgcgcgttt cgatggttaa tgtattcggt ttttcgatta cgatgctttt
    30061 catttttcgc tccttaccag ttccacagtg tgccgtcttc aagacgggcc accggcaaat
    30121 aggctggatc gtacggatat ttcgccgcca gtttttcatt aaactcaatg cccagtcctg
    30181 gcttgtcgcc cggatgcata tagccgccct cgaacgtcca gttatgcggg aaaacctcca
    30241 gcatctgttc ggagtagccc ataaactcct gcacgccaaa gttaggcacc cacaggtcaa
    30301 aatgtaatgc cgcggccata caaaccggcg acagatcgga cggcccatgc gaaccggtac
    30361 gcacctggta gagcgaggca aaatcggcaa tgcggcgcat cccggtaata ccaccggcat
    30421 gggtaatcgt ggtgcggata tagtcaatca attgctcttc aatgagctgt ttgcaatccc
    30481 agatactgtt aaagacttcg cctacggcaa tcggcgtaac cgtatgctgg cggatcaggc
    30541 ggaagcactc ctgattttca gccggcgtcg ggtcttccat ccagaacaaa cgatagtctt
    30601 caatacattt gccaaagcgg gcagcctcaa taggcgtcag tcggtgatgc atatcgtgca
    30661 gaagatgttc attaaacccg aacgtattac gcacggcgtc aaacagcttt ggcgtaaaat
    30721 cgagatactt ttccgttgac cacaattgtt cttccggcca ctggcctttt gtcgcgggct
    30781 cataggccag tcccttacct ttcgccatgc cgtaggtggt tttcatcccc ggaacgccgc
    30841 actgcacgcg gattgctttg aacccttgct ctttatgacg cgcgtagtct tccagcacat
    30901 cgtcgatggt gtggcctgta gtatggcaat acaccatgac gccttcacga gaagcgccgc
    30961 cgagtaactg atacaacggc atattggcgg ctttggcttt aatatcccat agcgccatat
    31021 caactgcgga aatggcggac atggtgacag gaccacggcg ccagtacgca cctttgtaga
    31081 agaactgcca gatatcttcg atgcggtgag catcccgccc gatgagttgt ggacacagat
    31141 gatcggtaag gtacgaggcc accgagagct cgcgtccgtt cagggtggca tcccccagac
    31201 cggtgatccc gtcttccgtg gttattttta aggtgacgaa gttacgccct ggacacgtaa
    31261 caaaaacttc agcccctaca atcttcattt ttattcctta catcgcatta tgggatgcag
    31321 gaaatttacc caactgagct actaccatac aagtatattt atctaaaaag cgctgccaga
    31381 tcacaaaatg ttctggcagc gcggcaatgt tacgtacgcc cccatccaac gacgataatc
    31441 agcattccac acagcgcgat cagcgcgccg ctccagtcat aaaccgtgag ccggacgcca
    31501 tcgacaacac gtaaccacag gagcgcagta cagacatata ccccaccgta agccgcataa
    31561 acccgcccac tcgccgccgg atgcaaggtc aaaagccaga cgaataacgc gagtgacgcg
    31621 gcagcgggca gaagccacca cacgctggcg ccgcgcttaa tccatagcca gggaagaaaa
    31681 catccaatga tttcacagag ggcggtgaca aagaaaagca gagtcgtctt tagcatgaga
    31741 ttcatttggt tacgaaatga taagtgataa tacaacagaa tatcgttacg gttatccggc
    31801 cattcttgtg tatatgccag gcataaggat tggtgtagaa tttacaggtg gtttaccgct
    31861 ttttcccctc taatgaaagg atgttgtgat gaacaatacg ctgagcaaac gcctttgcct
    31921 gacggcaatg cttacgttgg cggccgttgt atatactact tccgcattcg ctgaaaccag
    31981 taaactggtg attgaatcgg gagatagcgc acaaagtcgt caggaagcgg cgatggaaaa
    32041 ggaacaatgg aacgacactc gcagtctgcg tcagaaagtg aatacccgcg cagaaaaaga
    32101 gtgggacaaa gccgatgccg cctttgataa ccgcgataaa tgcgagcaaa gcgccaacat
    32161 caacgcctat tgggaaccca atactctgcg gtgtctggat cgtcgtacag gtcgcgttat
    32221 tacgccctga tgcaggataa ctaaaaggaa gtgtaaggat acagtatgac aagtgactac
    32281 aaggtcagac tgcgcccgct tgagcgtgaa gatttacgat ttgtccacca gcttgataat
    32341 aatgccagcg ttatgcgtta ctggtttgaa gagccgtatg aggcttttgt cgaactgtcg
    32401 gatctctacg acaaacacat ccacgaccaa agcgaacggc gctttgtcgt cgaatgcgac
    32461 ggtgaaaacg ccggactggt agaactggtg gaaattaacc atgtgcatcg gcgggcggaa
    32521 tttcagatta ttatttcgcc ggagtaccag ggaaaaggcc tggcgtcacg cgcggccaaa
    32581 ctggcgatgg attacggatt taccgtactc aatctctata aattgtattt gatcgtcgat
    32641 aaagagaatg aaaaagcgat tcacatctac cgtaaactcg ggtttagagt agaaggcgag
    32701 ctgattcatg agttcttcat taacggcgaa taccgtaaca ccatccgcat gtgtatcttc
    32761 cagcagcagt atctggatga acataaaacg tccagttcta cgctcctgaa acccaccgcg
    32821 cagtaagcgc ggcgcggtag tcacggagag tcgcaccgcg cccggtttag tagtaatcga
    32881 tacgattttt aatggtgtaa tggtgggaca ctgccggctt aacgctctca tcgacgataa
    32941 caagccggca gtcaacaggg ttcgcgtacg catcatattc gcagctctgt gtgacgttgc
    33001 cgacctgtcg atcatccacc cggctgactg ccgtataatc cagcttttta cgggagtccg
    33061 tggagagttt tgccgtcaca gagagcgtat tctgcgagtt tatggttgtc ttacctaacg
    33121 gataaccttc gctatcatag cggtactcga ccttcatctc tttgcccgtc gccgatacca
    33181 caaaaccgtt gtcgtccgtt tcccaagtca cgcccgccga aggcaacgcc gccagctggc
    33241 acttcccctg taactgcacc tttttttcca gcgtctgagc atcccggtaa taattagcat
    33301 ccagcacgag cgccagcccc gtattattct ccagatcgtg taactcaagc gtatcaaaac
    33361 agccttcctg tgaaagcgta ccggtgacct gcttcgccac ttcgccattc tcactcatca
    33421 acgtctggct gaaatccttt accggaccac gtaatggatc aaaatcaaat tcgttcgaaa
    33481 aactggccat ttccggcgta aaagactcgg gggatttcgg gttatcacaa cctgccagta
    33541 tcatgcacaa taacgtcagt aaaaggggtt tcttcacgcg tgtcaccagg atgaaaagat
    33601 atttatcatc atattagcaa atacagttat ttacacgaaa aatgctaagc ttagaacatc
    33661 gtcattaatc acaggagttc atgatgaaaa tcgcaactgc aatagccgct ctggcgttag
    33721 tcagcgcccc ctcgctggtg atggcggcac cgggatcgtg cgagagagta aaaagcgata
    33781 tcgaacaacg tatcatcaat aacggcgtgc cggcggataa ttttacgctc actatcgttc
    33841 ctatacgacc aggccgatca gccggactca caggtggtgg gccattgcgc gaacgacacg
    33901 cataaaattc tttatacccg caccagcagc ggcaatgcgc cagccaatac ctctcccgct
    33961 caggacggtt catccgccga accacaataa cctcctcctg ccctccgggt ccggagggta
    34021 acgctctttg acatggatta ataatcctta ctcccaaagg ggtaaactca ttacatcatt
    34081 agcatgttaa taatttcgct atagtcatta atatatagcg aaacgataac gacaatggag
    34141 tgagtgatgc ccggagaaaa gcagcaaaca ggcgttagcc gcaggacgtt agtgaaatca
    34201 gcggcgcttg gctcactggc gctggctgcc ggaggcgtat ctttaccgtt tgggatgcgt
    34261 accgcggccg cggcggtgca gcaggctatg cgcaacgaag aagataaaat cgtctggggc
    34321 gcctgttcgg tcaactgcgg cagtcgctgc gccctgcgtc tgcatgtaaa agataatgaa
    34381 gtctggtggg ttgaaactga taacactggc gacgatgtct acggcaatca tcaggttcgc
    34441 gcctgtctgc ggggccgttc aatccgtcgg cgcattaacc atccggatcg ccttaactat
    34501 cccatgaaac gcgttggccg ccgcggcgaa ggcaaatttg aacgcattag ctggcaggaa
    34561 gcgctggaca ccattagcgc cagcctgaaa aagaccgtag agatctacgg caatgaagcc
    34621 gtttatatcc actattcatc cggcatcgta ggcggcaaca taacccgctc gtcgccttcc
    34681 gcctcgccgg tgaagcgttt gatgaactgc tacggcggtt cgttgaatca atacggctca
    34741 tacagtaccg cgcaaatttc ttgcgccatg ccctacacct atggatccaa cgacggcaac
    34801 agcacatctg atatcgaaaa cagtaaactg gtggtcatgt tcggcaataa tccggctgaa
    34861 acacgcatga gcggcggcgg cattacctgg tttctggagc aagcgcgtga acgctcaaat
    34921 gcgcgcatga tcgtgataga tccgcgctat accgataccg ctgccggacg tgaagacgag
    34981 tggataccta ttcgccccgg caccgacgcc gcgctggtgg cgggaattgc ctgggtattg
    35041 attaacgaaa atctcgttga ccagcctttt ctcgacaact attgcatcgg ctacgatgaa
    35101 aagacccttc cggctgacgc cccccccaat ggccattata aggcttatat tttgggccag
    35161 ggcgaggacg gtatcgccaa aacgccgcag tgggcgtcac acattaccgg catccccgcc
    35221 gatcggatta tcaaactggc gcgcgagata ggtagcgtca agccggccta catctgtcag
    35281 ggttggggcc cgcagcgtca ggcgaacggc gaacaaaccg ctcgcgccat cgccatgttt
    35341 ccgattctga ccggcaacgt cggcattcat ggcggtaatg gcggcgcacg cgaatccact
    35401 tacaccatta ccattgaacg tctgccggtc ctggagaatc ccgttaaaac cgccatctcc
    35461 tgctttagct ggacggacgc cattgcgcgc ggcccggaaa tgaccgccct gcgcgacggc
    35521 gtacgcggca aagataagct ggatgtcccg atcaaatttc tatggaacta cgctggcaac
    35581 accctgatta atcagcattc ggatattaat aaaacccatg aaattcttca ggatgaagca
    35641 aaatgcgaaa tgattgtggt catcgacaat tttatgacct cttccgcgaa gtacgccgat
    35701 attttactgc cggatctcat gaccgtcgaa caggaagata tcatccccaa tgattacgcc
    35761 ggcaatatgg gatatctgat ttttatccaa ccggcgacga cgcctaagtt tgaacgcaag
    35821 cccatctact gggtactcag cgaaatcgcc agacgcctcg gtgacgatgt gtatcagcgg
    35881 tttaccgaag gccgtaccca ggcgcaatgg ctgcaatatc tgtacgccaa aatgcaggca
    35941 agagatccgg cattgcccgc gtatgacgag ctaaaaaaaa tgggcatcta taaacgcaaa
    36001 gatcccaacg gccactttgt cgcctataaa aaatttcgtg aagatccgca ggccaatccg
    36061 ttaaaaacgc cgtccggtaa aatcgaaatc tactcaagca aactcgctca catcgccagt
    36121 acctgggagc tggcggaagg cgacgtgata agcccactgc cgatttatac ccctactttt
    36181 gaaggatggg acgatccgaa gcggagcacc ttcccgctac agctgtttgg ctttcactat
    36241 aaatcccgta cccattcaag ctacggcaat attgatgttc tgcaggccgc ctgtcgccag
    36301 gaggtgtgga taaatccgct tgatgcgcaa aaacgtggta tcgcgaatgg cgataaggtt
    36361 cgcgtcttta acgatcgtgg agaagtgcgt ctacccgcca aggtcacgcc gcgtattctg
    36421 ccgggcgtca gcgcgatggg tcagggcgca tggcataatg cggatatggc tggcgataaa
    36481 attgaccacg gcgcctgcat caatacgctc acgacgctgc gtccttcccc cctggcaaaa
    36541 gggaatcctc aacatacaaa tctggtggaa atcgaaaaaa tctaagccgc ctgctccggg
    36601 gcgtttttac gcgcccggag ctccccgttt tgcgaacaca acgacattta aaactctttt
    36661 ttggatgagc atagtgagga gctgttatga aaatcaccaa ccctgaggca ttaatggcgg
    36721 ccagtatcag ccgacgaagc ctggtgaaaa cctccgctat cggtagcctt gcgcttgcca
    36781 gtagcgcttt cacccttccg ttctcccgca tcgcccacgc cgcagcagac ctcgcatctg
    36841 gcaatatggc agaaaaagcg gtctggagtt catgtaccgt taactgcggc agccgctgcc
    36901 tgctgcgcct gcacgtaaaa gatgacaccg tatattgggt tgaatcagat accacgggca
    36961 acgatgaata tggcaaccat caggtacgcg cctgcctgcg cggtcgttct attcgtcgcc
    37021 ggatgaatca tcccgatcgc ctgaaatatc cgatgaaacg cgttggtaaa cgaggagaag
    37081 gcaaattcga acgtatcagt tgggatgaag cgttggatac catcggcgat aaccttaaac
    37141 gcatcctcaa ggactacggc aacgaagcgg tacatgtcct ttacggtacc ggcgtggacg
    37201 gcggcaatat taccaattct aacgtaccgt atcgcctgat gaacgcctgc ggcggctatc
    37261 tcagccgtta cggtagctac agcaccgccc aaatcagcgc ggccatgagc tatatgttcg
    37321 gcggcaacga cggcaacagt ccggatgata tcgccaatac aaaactggtg gtgatgtttg
    37381 gcaataaccc cgcggaaaca cgtatgagcg gcggcggcgt gacatactat gtcgaacagg
    37441 cgcgcgaacg ctccaacgcc cggatgatcg tcattgaccc gcgttataac gacactgctg
    37501 ccggccgcga agacgagtgg ctgccgattc gcccaggtac cgatggcgcg ctggcggcgg
    37561 caatcggctg ggtgctgatt accgaagatc ttattgataa accgtttctg gataaatact
    37621 gcatcggcta cgacgaaacc actctgcccg cctcggcccc gcgtaacgcg cactataaag
    37681 cctatatttt gggtcagggc gaagacggta ttgctaaaac gccgcaatgg gccgcgcaga
    37741 ttaccagtat tccggcggaa aaaatcattc aactggcgcg ggaaatcggc tcggcgaaac
    37801 cggcttacat ttgccagggc tggggaccgc aacgccactc taacggggag cagaccgcac
    37861 gcgcaatcgc catgttgtct gtactcaccg gtaacgtcgg cataaatggc ggtaattccg
    37921 gcgtgcgcga aggcacctgg gatctgggcg tcgaatggtt tcctatgctg gagaacccgg
    37981 taaaaaccca gatttcggtc tttacctgga ccgacgctat cgatcatggc gcggaaatga
    38041 ccgccacacg cgacggcgtg cggggaaaag acaagctcga cgtgccgatc aaatttttgt
    38101 ggtgctacgc cagtaatacg ctgatcaatc agcatggcga tatcgcccac acccacgagg
    38161 tgcttcagga cgacagtaaa tgtgaaatga tcgtcggcat cgagcacttt atgaccgcgt
    38221 cggcaaaata ttgcgacatt ctgctgcctg atttaatgcc gaccgagcag gaagatctga
    38281 tttcccacga atccgcaggc aatatgggct atgtcattct tggtcagccc gccacctcgc
    38341 cgaaatttga aagaaagccc atttactgga cgctcagtga agtggctaaa cggcttggtc
    38401 cggacgtata ccagaccttc acagaaggcc gcacgcagca tgagtgggtc aaatacctgc
    38461 acgcaaaaac caaagcgcgt aacccggaaa tgccggatta cgaagagatg aaacagacag
    38521 ggattttcaa gaaaaaatgc ccggaggagc actacgtcgc tttccgctca ttccgcgaag
    38581 accctgccgc caacccactg aaaacgccgt ccggtaaaat cgaaatctat tccgagcgtc
    38641 tggcaaccct cgccaacacg tgggagctga agaaagatga gattatccat cctttacccg
    38701 cctatacgcc aggctttgac ggttgggacg atccgcttcg tcagcgctac ccgctacagc
    38761 taaccggctt ccactataaa gcgcgtaccc actccagcta cggcaatatc gacgtcctgc
    38821 aacaggcgtg tccgcaggag atctggatca acccgattga tgcgcaagcg cgcggcattc
    38881 agcacggcga caccgtgcgg gtctttaacc agaatggaga gatgctcatt ccggcaaaag
    38941 tcacgccgcg catattgcct ggcgtcaccg ctatcggcca gggcgcctgg ttaaatgccg
    39001 acatgtttgg cgacaaagtc gatcgcggcg gctccattaa cattctgacg tcgcaccggc
    39061 cttccccact ggcgaaaggt aatccgtcac acagtaatct tgttcaggtt gaaaaggcgt
    39121 aaggagtaac cgatgacaac ccagtatgga ttttttattg attccagccg ttgcaccggt
    39181 tgcaaaacct gcgaactggc ctgcaaggac tacaaagatc tcactcccga cgtcagcttc
    39241 cgccgcattt atgagtatgc gggcggtgac tggcaggaag ataacggcgt ctggcaccag
    39301 aacgtctttg cctactatct ctccatctcc tgtaaccact gcgaagaccc ggcctgtacc
    39361 aaagtctgcc cgagcggcgc gatgcacaag cgcgatgacg gttttgtggt ggtgaatgaa
    39421 gaggtctgta tcggctgccg ctactgccac atggcctgcc cgtacggcgc gccgcagtac
    39481 aacgcggcca aaggtcatat gaccaagtgc gacggctgtt atgaccgggt ggcggaaggc
    39541 aagaaaccga tttgcgtgga atcctgcccg ctgcgggcgc tggatttcgg cccgatagac
    39601 gaactgcgca aaaaacacgg tgagctggct gccgtcgcgc cgttgccgcg cacgcatttc
    39661 acgaagccga atattgtgat taaacccaac gccaacagcc gcccgaccgg ggacaccacc
    39721 ggttatctgg ccaatccgaa ggaggtataa gatgggaagt ggatggcatg aatggccgct
    39781 ggtcctgttt acggtgctgg gtcaatgtgt ggccggggcg ctgatcgtga gtggatatgg
    39841 ctggttaacc accaaagacg atgtggcaaa acaacgcatc gtgcgcagca tgttttttct
    39901 gtggctggtg atgggactgg gattcctcgc gtcgattatg catctcggct tgccgatgcg
    39961 cgcgtttaac tcgcttaacc gcgtaggcgc ttccgcactg agtaatgaaa tcgccgcagg
    40021 atcggtgttc tttgccgtag gcggcatctg gtggctggtg gcggtactcg gtaaaatgcc
    40081 cccggcgctg ggtaaagtgt ggctgctggt cagtatggcg ctcggcgttg cattcatctg
    40141 ggcaatgacg ctcgtttatc agatagatac cgtgccaacc tggtataatg gctacaccac
    40201 gctggccttt ttcctcacgg cattcctgtg cggtccggtg tttgcggcgc tactactacg
    40261 catcgcgcgc gtcccatttt gcagcgtgac gtttgccagt attagcggcc tggcgttggt
    40321 ggtgtgcgtg gcggtcatcg tactacaggg actgtccctc tcagccattc acagttccgt
    40381 gcaacaggcc agccatctcg caccggatta cggtatgcta caggtctggc gcattgtctt
    40441 gcttgctgcc ggattaggtt gctggctatg tccactaatc cgtcgccgcg aaccgcatac
    40501 cgttggtttg ctgctcggtg tcgtactggt gctggcgggc gaaattattg gccgcggact
    40561 tttttatggc ctgcatatga ccgtaggtat ggccgtcgca ggttaattta tgcgtgcggg
    40621 gcgacccgca cctttcggga ttgtttgaat gaccactttt ttacaacgtg atgattttgc
    40681 agtaacggcg cgtgttcttg gcgcgttgtt ttattattcg ccggaaagcc acgaaaccgc
    40741 tcctctggtc caggcgctat taaacgacga ctggcaggcg cagtggccgc ttgatgccga
    40801 ggcgcttgca cctgtggcgg ctatgtttaa gacccacagc gaagagtcgt tgccacaagc
    40861 ctggcagcgc ctgtttatcg gcccttacgc tctgccgtct ccgccgtggg gttccgtctg
    40921 gctggatcgt gagagcgtat tatttggcga ttctacgttg gcgctacgtc agtggatgcg
    40981 cgaaaacggg attcagtttg aaatgcagca aaacgagcca gaagatcatt ttggggcgct
    41041 gttgttgctg gcggcctggc ttgccgagaa tggccgtcat catgaatgcg aacaactcct
    41101 ggcctggcat ctgtttccgt ggtcgccccg ctttctggac gtatttatcg atcatgccgg
    41161 gcatccgttt tatcaggcgt tggggcaact ggcgcgtctg actctggcgc aatggcaagc
    41221 tcaactcatt attcccgtcg ctgtaaaacc gttattccgt taatccccac aaaaggcagg
    41281 attttacctg ccttttctcc cattgtggcc tatttttacc tacaaaaagt gacaacgtca
    41341 cacctcgctt ctatttttaa gataattctt tatcgtgaat gttcacgcta agccgcataa
    41401 gggcaaaaca taattgttaa tagatgttta acagtgttaa acatcacgct ccgctggaat
    41461 ccttcccaac ctgttgctat agctcaaagc accctgccgg aacatggcat aacaacacgc
    41521 gactcttaac gtcgccataa cacatgcaaa cagggagaca caccgcaatg cacatcctca
    41581 ccctaaaacg cgtacttggg ttcactatcg tcattctgct gttactggcg ctgtttatct
    41641 ggggaatcgg tctggagacg ctgaaagcgc gtcaggtcga tctgctgtat ctcggacaac
    41701 ggcatttgat gctggtcttt acgtccatgt tttttgcttt actggtcggt atcccgagcg
    41761 ggattttact cagccgacct gcggcaaaag gatttgctga atatgtcatg caaatcttta
    41821 atgttggtaa taccttgccg ccactggccg tcctggcctt agcgatggtg attatcggga
    41881 tcggcgatac gcccgccatt gtcgcgctat ttctggcttc tcttctgcct atcgtccgca
    41941 atacctatgc aggcctctgt tccgttcccg cctcactgat tgaagcggcg aacgggattg
    42001 ggatgacaaa atggcagcgg cttcgccagg tagagctacc taatgcgtgg ccagtgatgc
    42061 tgtccggtat tcgcatcgcg accgccatca atgtcggcac cgcgccgctg gcctttctga
    42121 tcggcgccag cagctacggc gagctgattt ttccggggat ttatctcaac gattttccga
    42181 cgttgattct cggcgcaacg gccacggcgt tattcgcgct gattcttgac actctgcttg
    42241 cctggtttgg gcgacgcctt agccctcata ccgtctgaac gcataaataa caataaggag
    42301 cgttaaatga gattcaaaaa acacctgttg ggatggcttg ccacaacgct gttgttcagt
    42361 agccagacgc aggccgcgcc gctggttctc gccaccaaaa gctttaccga gcagcatatt
    42421 ctttccgcta tgaccgttca gtatttgcag aagaaaggct ttcaggttca gccgcaaacc
    42481 aatatcgccg cggtgatttc acgtaatgcg atggtgaata aacaaattga tattacctgg
    42541 gaatataccg gtacatcgct gattattttc aaccgtatcg ataagcgcat gagtccacag
    42601 gaaacctacg acacggtaaa acgcctggat gcgaagctgg gcctggtatg gctcaaaccg
    42661 gctgacatga acaatactta cgcgttcgcg atgcagcgta aacgcgccga gtcggaaaat
    42721 atcaccacca tctcgcaaat ggtggcaaaa atcgaacaag tccggcagaa cgatcctgac
    42781 cacaactgga tgctcggcct cgatctggaa tttgccgggc gcagcgacgg gatgaagccc
    42841 cttcagcaag cctaccagat gcagctcgat cgcccgcaaa tacgacagat ggacccaggg
    42901 ctggtctata acgccgttcg ggatggactg gttgacgccg ggctggtcta taccaccgac
    42961 ggacgggtga aagggtttga tctgaaagtg ttggaagatg ataaaggctt ctttccaagt
    43021 tacgctgtca cgcccgtggt gcgtaaagag gtgctggaag ccaatcctgg tcttgatgac
    43081 gccttaaaca ccctttccgg cctgctcaat aacgatgtga tatcgaccct aaacgcccag
    43141 gtcgatatcg agcatcgcac gccgcaacag gtagcccatc aatttttgca ggacaaaggt
    43201 ctgctgtaag gagcgcctat ggatacgata cattatatgc tggataacgc aggctatctc
    43261 gccagcctta cctttcagca tctctggcta gtcgcgctgg ccgtcggtct ggcgattatc
    43321 atcggcgtac cgttaggcgt tttgattgta cgccacaaat ggctggcaac gccggtattg
    43381 ggcgccgcca cgctacttct taccattccg tctatcgcgc tgtttggatt aatgatcccg
    43441 ctcttttcgc tgatcgggca tggtattggc gttctgcccg ctgtgacggc cgtttttctc
    43501 tactctttac tgccgattgt ccggaatacc catactgcgc ttgatagttt gccgcccggt
    43561 ctgcgtgaag cgggacgcgg catcggtatg actttctggc aacggctgcg ctgggtcgaa
    43621 atcccaatgg ccctaccggt tattttcggg ggtatccgca ccgcggtagt gatgaatatc
    43681 ggcgtgatgg cgattgccgc ggtgatcggc gccggcggtc tggggctgct actgttaaac
    43741 ggcattagcg gcagcgatat tcgcatgtta attgccggcg cgctgatgat ctgtctactg
    43801 gcaattgtac ttgactggct gttgcatcgt ctgcaagtcg tactggcacc taaggggata
    43861 cgataatgat aaaactggaa aatctcacca aacaatttgt acagaaaaag ggtcagccgc
    43921 taaaagccgt cgacaacgtc aacctgaacg tgccggaagg cgaaatgtgc gtcttactcg
    43981 gtccctccgg ctgcggcaaa accaccacgt taaagatgat caaccggctg atcgcgccca
    44041 gcagcggtaa tattcttatc aacggcgaga ataccaacga tatggatacg gtaacgctac
    44101 gccgcaatat tgggtatgtt atccaacaga tcggcctgtt tcctaatatg acgattgaag
    44161 aaaatattac cgttgtgccg cgcatgttgg gttgggacaa agcgcgctgc aagcaacgcg
    44221 ccgaagagtt gatggacatg gtggcgctgg atgccagaaa atttctgcat cgctatccaa
    44281 aggagatgtc cgggggacag caacagcgta ttggcgtgat ccgcgctctg gccgccgatc
    44341 cgccggtact gctgatggat gagcccttcg gcgcggtgga ccccattaac cgcgaagtga
    44401 tccagaacca gtttctggat atgcagcgta agctaaaaaa gaccgtgatg ctggtcagcc
    44461 atgatatcga cgaagcgcta aaactcggcg accgtatcgc cgtgttccgt caggggcgaa
    44521 ttgtacagtg cgccagtcct gatgaactgc tggccaagcc ggctaacgag tttgtcgggt
    44581 cgtttgtcgg tcaggacaga acgttaaagc gtttgctact ggtctccgca ggcgatgtga
    44641 ccgaccaaca gccaaccatt accgcgcggc cttccatgcc gttaagcgag gcgttcggca
    44701 ttatggatga tcacgatatt cgcgccatta ccgtcattga caacgacggt aagccactgg
    44761 gatttgtgaa gcgccgggag gcgcggaacg ccagcggaat ctgcgccgat atcacccatc
    44821 ctttccgtat tacgggcaaa gcggaagata atctgcgtat tgtgctgtcc agattgtacg
    44881 aaagtaatac cagctggatg ccgatcgttg atgaagacgg acgctataac ggtgaaatct
    44941 ctcaggatta catcgccgat tatctcagct caggccgcac tcgtcgggcg ctaaatattc
    45001 acgaaagcag ctaacgttgc cgccggatcg cctctcgcta tccggcagta tcattattgt
    45061 acgcaatatt atatcgcaca tagtgctttt gcgtctgacg ccatttcccc gcagaatagg
    45121 ctatcctgaa actccctgtt tacccgctca tgcatcgttt acacgcttac ccggatctgc
    45181 gcgcgatgtt tcgtcgcctg ctgatcgcta cgctcatcgg tattctcgcg gcgctggctg
    45241 tcgccgcctt ccgtcatgcg atgcaattgc tggagtggat tttcctgagt aatgacaccg
    45301 gcagtctggt gaatgcggct gaggggcttt cgccctggcg acggctgatt acgccggcgc
    45361 ttggcggcct ggccgctggt ctgttgctgt gggggtggca aaaaatgaac caacagcgcc
    45421 cccatgcgcc cactgactat atggaagcat tgcaaaccga cgggcaattt gacgttggcg
    45481 ccagtctggt gaaatcgctg gcctcgctgc tggtcgtggt cagcggcagc gcaattggtc
    45541 gcgaaggcgc aatgatcctc ctcgccgcgc tggcggcgtc cagctttgcc cgacgcttca
    45601 cgccgcgtga ggaatggaaa ttatggatcg ccagcggcgc cgctgcgggc atggcgggcg
    45661 cttaccatgc gccgctggcg ggcagcctgt ttatcgcgga gatcctgttc ggtaccttaa
    45721 tgctggcttc cctcggcccg gttgtcgttt ccgccgtcgt cgccctgcta accacccatg
    45781 tattaaacgg tagcgattca ctactctata ccgtacatct gaccgttgat ctctacgcgc
    45841 gggagtacgt catgatagtc agtaccggtc tggtcgccgg tctgtggggt ccgttgctga
    45901 tgtggctgat gacggccagc cataatagtt tcttacgctt aaaactgtcc ccgccctggc
    45961 aactggcgtt gggcgggctt attgtcggat tactgtcgtt actcacgccc acggtatggg
    46021 gaaacggcta tagcgtcgta caatcatttt tgctctcccc gccgctattc tcgctgattg
    46081 gcggaatttt tgcgtgcaaa atcctggcgg tgctcgccag cagcgggtct ggcgcgccgg
    46141 gcggcgtctt tacgccaaca ttatttgtcg gattatccat tggaatgttt ctgggtcgga
    46201 tatggggatt ctggctgcca ggctcggatg aaatagcgat tttattgggg ctggcgggta
    46261 tggcgacgct actggcggcg acaactcatg cgccgataat gtccaccctg atgatttgtg
    46321 aaatgaccgg cgagtatcag ttactccccg gtctgctgat tgcctgtgta gtcgcgtcag
    46381 tgctctcgcg aacgttacgc catgattcta tctaccgcca gcacgctgcc gagcattgac
    46441 aaacgaatat actgccccag ctcacgctgc tcggcgcgcg gcaggtacgg taactcgcca
    46501 atcagcggcg ctggcagttt tttcccaagc acatcaataa tttcagcata atgcgccagg
    46561 ccaggattga tacgattcgc cacccagcca attaagggca gtccatcatt agcgacagct
    46621 tgcgcagtca gtagcgcatg attaatgcac ccctcctgaa tccccaccac catcaatacc
    46681 ggtaactgtt cctgtaccac ccattcggac aatggacgta aatcattcat caaactacgc
    46741 cagccaccag tgccctccac aaccacgtgg tccactttat cgctcagact cgccagaccg
    46801 ttggacagca aggtgtaatt tataggacag ctatgcgcga cgctgctttc ttcttcgctt
    46861 aacgcgatcg gattaatcgc ctcatacggc aactccagcg aagagacgct ttgcaatacc
    46921 agagcgtctt tgttgcgcat cccttctgga gtctctttgc tccctttagc gacaggttta
    46981 taccctgcaa cgctcttacc acccgacgat aacgcttgta gtaatgcgcg ggaaaccacc
    47041 gtcttcccaa cagaagtgtc tgtacctgta ataaagaaac gcttcagcat cactaactcc
    47101 accgttatgc ttcgaaaata taagccagga aaataataca gtggagaaag tctaagatat
    47161 ggcaagggca atcagcttga gttagcgcaa atttttgtac aacagttaaa aaatgttaac
    47221 cctgtaatag acgaatcaac aaagagccgt tatacatcgc gtcttttacc aacgccgccc
    47281 cggccatcgt gctctggttg gtaaactgcg tgctttccac taccgtattc ctactgtagg
    47341 cgggcagcgc ctgctgacgg atactgtcag caatggccgg aaaaagaata tcagccgctt
    47401 tacttagcgg cgaaccaata agaatttttt gcggattaaa taaattcacc atgatagcca
    47461 gaatgcgtcc gacatgcgcg ccaacgccgc taataatatc ttttgctaat agatctccct
    47521 gcatcgccgc ctgacacagc gaatctaccg ttaacggctg gccatgcaac attgaactta
    47581 tcgactgatt aagccgaagc tgcgtaagtt ccagcacact atcgacgctg gcgatggtct
    47641 ccagacagcc atgattaccg caataacagc gcttaccata aggattgacc tgggtatgcc
    47701 caatctctac cagactgcta ctgcccgcat gaagcaaatg accgtcggtg ataacgcccg
    47761 cccccacatt atgatcaatc accacctgga taacgtcgcg cgcgccgcgt gaggcgccaa
    47821 aaagcgcctc tgccatcgtc caggcgctaa tatcatgctg aatgtaaacc ggtacgccgg
    47881 tgtgccgctc cagcgcatct cccaaaggca tctctttgac atcttcgtaa tacggcatcc
    47941 ggtgcacaac accgttttcg gtatcgataa tgcccggtaa cgtaatggca atggaggtca
    48001 aacgctccag tttctgctga tggcgggtaa aaaaccgatc aacgtgcgta ataattcgct
    48061 caagcaacgg cgtagcttcg tttaacggca gcgccagaca ctcttctacc accagtttgc
    48121 tgctaagatc gcgcagtgca aggaaaattt cgccacggct aatacgaata gataaatagt
    48181 gccaggcttc cgtttccacc atcagcccga cggcgggacg tccacgactg cccgcctctt
    48241 taatttcaag ttcctgaacc aaatgcgctt ccagcatttc gcgaacaatt ttcgtaatac
    48301 tggcaggcgc caactgcgcc agacgagaca ggtcaattcg cgataccggt ccgagctgat
    48361 caatcaggcg atacactgcg ccagcattgg tctgcttaat ttgatcgata tgcccaggct
    48421 gactatcagc aaccaccgct cactcccttt attttcgcgc tccgaaataa tctgtgtgct
    48481 atggtgaaac acttcaatac tcgccgtcaa ctttttgctt agccgtgtga ttaactgcac
    48541 attttcaccc tttttaagcg taattaatcc tgtcgggcag ccagtaatag cagttggcaa
    48601 aaccgctgta cggcatgact ctgttcatga tgctttggcc ataccagcca catttcagat
    48661 acggcgtcct cttctgccag gggaacccag cgcatctcgc tcatctgtac acgcttaaag
    48721 gatgccggca gaatcgagac gcccagtccc gccgccacca gaccgataat agtcattgcc
    48781 tcgccaacct cctgcgtgat ggtcggcgac aggttatagc gccgcatcag gccgagaata
    48841 tcgtcgtaga gacccgtccc gacatgcgga tcgaaaaaga cgaaaggttc ttccgccagt
    48901 tctgtcagac tgacgactgg cttttgcgcc agccgatgtt cgcgcgggat catggccata
    48961 agcggctcat gcaaaatcac ctcgcgatta agtgtgtctg gcagcggcgt attccgcagc
    49021 aagccaatat ccagtacgcc ttcgttgagc ggcgcgattt gctcacgcgt attcatttca
    49081 cgcgtttgca tatgcacccc cggataggac tggcggaaca acgaaaaggt atgcgatacc
    49141 gcccgaataa aaggcgctga agacgtaaaa ccaatacgga tttcgcccgc ttcgccctga
    49201 tgcaaccgct cggcgcgagc ggcggcgtcg tttaccagac tcaggatgtg tcggctatcc
    49261 gccagaaact gtcgcccggc ggcggttaac gctacgctgc ggttggtccg cgccagtaat
    49321 cgcgcaccga cctgctgctc cagaatttgt atctgctgac tgagcggcgg ctgcgagata
    49381 ttgaggcgcg cggcggcgcg accaaaatgc agctcttctg ctaccgccac aaagtaacgt
    49441 aaatgacgta attcgatatt catattttta acgtcttatt tgagacaatt aatatattag
    49501 acagaatatt ttgctttttc tatgctttac atgtcggtta tacccgtctc ctgttgacgg
    49561 agatgtaaag caaggattta acgtgagtcg tacaactatt ctcgatgacg ccacggcgag
    49621 cgatatcgat gaacaacgcc attctcagcc ggttcaattt attaaacgcg gtacagcgcc
    49681 tttcatgcgc gtcacgctgg ctcttttttc cgcgggcctg gcgactttcg cactccttta
    49741 ttgcgttcag cctatactac cggtactttc ccaggagttt ggcgtctccc ccgccagcag
    49801 cagcgtttca ctttctattt ctaccgccat gctggctatc ggcttacttt ttaccggccc
    49861 gctttctgat gcgataggcc gtaaaccggt gatggtcacc gccttgttat tagcctcctg
    49921 ctgcacattg ttatcaacca tgatgaccag ctggcatggt attctgatta tgcgcgcgct
    49981 gatcggtctg tcgttaagcg gcgtcgccgc ggtgggaatg acctacctga gcgaagaaat
    50041 ccatcccagc tttgtcgctt tctctatggg gctctatatt agcggtaatt ccatcggcgg
    50101 gatgagcggg cgtttattaa gcggcgtcat gaccgacttt tttaactggc gcatcgcgct
    50161 ggcggccatc ggatgctttg cgctggcgtc cgcgctgatg ttctggaaga ttttacctgc
    50221 ctcgcaacat ttccgtccca cgtcgctacg gcctaaaacg ctatttatta atttccgtct
    50281 ccactggcgc gatcgagggt taccactgct gtttgcggaa ggttttttac tgatgggcgc
    50341 gttcgtcacc ctgtttaact acattggtta tcgcctgatg ctctccccct gggaattaag
    50401 ccaggccgtg gtcggactgt tatccgtagc ctatctcacc ggcacatgga gctcgccgaa
    50461 agctggcgca atgacctcac gctatggccg ggggccggtg atgctgttct ctaccgcagt
    50521 aatgctgggc gggcttttac tgacgctttt tacctcgctt tggctgattt ttgccgggat
    50581 gctgcttttt tccgccggct ttttcgccgc gcactccgtg gccagtagct ggattggccc
    50641 gcgtgcgcgc cgggcgaagg gacaggcctc gtcactttat cttttcagct attatctggg
    50701 gtccagtatt gccgggacgc taggcggtgt attctggcat agttacggct ggaacggcgt
    50761 aggtggtttt atcgcgctaa tgctggtgct ggccatcctg gtcgggacgc ggctacatca
    50821 tcgtcttcac gcctgaaaa
//
LOCUS       DAJVBX010000009        49932 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.009, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000009 DAJVBX010000000
VERSION     DAJVBX010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 49932)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49932)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49932
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.009"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..961
                     /gene="ssaU"
                     /locus_tag="OPV72_000459"
     CDS             <1..961
                     /gene="ssaU"
                     /locus_tag="OPV72_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="SPI-2 type III secretion system apparatus
                     protein SsaU"
                     /protein_id="HCR9912854.1"
                     /translation="LIALYLYFHFFTEKMILILIESITFTLQLVNKPFSYALTQLSHA
                     LIESLTSALLFLGAGVIVATVGSVFLQVGVVIASKAIGFKSEHINPVSNFKQIFSLHS
                     VVELCKSSLKVIMLSLIFAFFFYYYASTFRALPYCGLACGVLVVSSLIKWLWVGVMAF
                     YIVVGILDYSFQYYKIRKDLKMSKDDVKQEHKDLEGDPQMKTRRREMQSEIQSGSLAQ
                     SVKQSVAVVRNPTHIAVCLGYHPTDMPIPRVLEKGSDAQANYIVNIAERNCIPVVENV
                     ELARSLFFEVERGDKIPETLFEPVAALLRMVMKIDYAHSTETP"
     gene            complement(1119..1195)
                     /locus_tag="OPV72_000460"
     tRNA            complement(1119..1195)
                     /locus_tag="OPV72_000460"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1159..1161),aa:Val,seq:gac)
     gene            complement(1206..1282)
                     /locus_tag="OPV72_000461"
     tRNA            complement(1206..1282)
                     /locus_tag="OPV72_000461"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1246..1248),aa:Val,seq:gac)
     gene            complement(1434..2807)
                     /gene="mdtK"
                     /locus_tag="OPV72_000462"
     CDS             complement(1434..2807)
                     /gene="mdtK"
                     /locus_tag="OPV72_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460388.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MATE transporter MdtK"
                     /protein_id="HCR9912855.1"
                     /translation="MQKYTSEARQLLALAIPVILAQVAQTAMGFVDTVMAGGYSATDM
                     AAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLV
                     MIVLWNAGYIIRSMHNIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPG
                     MVMGFLGLLVNIPVNYIFIYGHFGMPELGGIGCGVATAAVYWVMFIAMLSYIKHARSM
                     RDIRNEKGFGKPDSVVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQI
                     ALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLGVGICMAVVTAIFTV
                     TLRKHIALLYNDNPEVVALAAQLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFFITF
                     TAYWVLGLPSGYILALTDLVVDRMGPAGFWMGFIIGLTSAAVLMMLRMRYLQRQPSAI
                     ILQRAAR"
     gene            3024..3665
                     /locus_tag="OPV72_000463"
     CDS             3024..3665
                     /locus_tag="OPV72_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HCR9912856.1"
                     /translation="MFTGIVQGTAKLVSIDEKPNFRTHVVTLPDYMLEGLETGASVAH
                     NGCCLTVTEINGNQISFDLMKETLRITNLGALRVGDEVNVERAAKFSDEIGGHLMSGH
                     IITTAEIAKILTSENNHQVWFKVQDASLMKYILYKGFIGVDGISLTVGEVTPTRFCVH
                     LIPETLERTTLGRKKLGERVNIEIDPQTQAVVDTVERVLATRENVVRNQADIG"
     gene            complement(3707..4855)
                     /gene="cfa"
                     /locus_tag="OPV72_000464"
     CDS             complement(3707..4855)
                     /gene="cfa"
                     /locus_tag="OPV72_000464"
                     /EC_number="2.1.1.79"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclopropane fatty acyl phospholipid synthase"
                     /protein_id="HCR9912857.1"
                     /translation="MSSSCIEEVSVPDDNWYRIANELLSRADITINGSAPSDIRVKNP
                     DFFKRVLQEGSLGLGESYMDGWWECERLDIFFSKVLRAGLENQLPHHVKDTLRILGAR
                     LINLQSKKRAWIVGKEHYDLGNDLFSRMLDPYMQYSCAYWKDADTLEAAQQAKLKLIC
                     EKLQLQPGMRVLDIGCGWGGLSQYMATHYGVSVVGVTISAEQQKMAQTRCEGLDVSIL
                     LEDYRDLNDQFDRIVSVGMFEHVGPKNYNTYFEVVDRNLKPDGLFLLHTIGSKKTDHN
                     VDPWINKYIFPNGCLPSVRQIAEASESHFVMEDWHNFGADYDTTLMAWHERFINAWPE
                     IAGNYNERFKRMFSYYLNACAGAFRARDIQLWQVVFTRGVENGLRVPR"
     gene            complement(5144..6349)
                     /locus_tag="OPV72_000465"
     CDS             complement(5144..6349)
                     /locus_tag="OPV72_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bcr/CflA family multidrug efflux MFS
                     transporter"
                     /protein_id="HCR9912858.1"
                     /translation="MQPGKGFLVWLAGLSVLGFLATDMYLPAFAAIQADLQTPAAAVS
                     ASLSLFLAGFAVAQLLWGPLSDRYGRKPILLLGLSIFALGSLGMLWVESAAALLTLRF
                     VQAVGVCAATVIWQALVTDYYPSQKINRIFATIMPLVGLSPALAPLLGSWILTHFSWQ
                     VIFATLFVITLLLMLPALRLKPSVKARTEGQDKLTFATLLRSKTYRGNVLIYAACSAS
                     FFAWLTGSPFILSAMGYSPAVIGLSYVPQTIAFLIGGYGCRAALQKWQGYQLLPWLLG
                     LYALSVIATWGAGLLNNASLVEILIPFCVMAIANGAIYPIVVAQALRPFPQATGRAAA
                     LQNTLQLGLCFLASLVVSWLISTPLLTTTSVMLSTVVLAALGYKMQSHADCAETGFPH
                     ANVAHDKSH"
     gene            6462..7394
                     /locus_tag="OPV72_000466"
     CDS             6462..7394
                     /locus_tag="OPV72_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCR9912859.1"
                     /translation="MWSEYSLEVVDAVARNGSFSAAAQELHRVPSAVSYTVRQLEEWL
                     AVPLFVRRHRDVELTPAGVWFLKEGRSVIKKMQITRQQCQQIANGWRGQLAIAVDNIV
                     RPERTRQMIVDFYRHFDDVELLVFQEVFNGVWDALSDGRVELAIGATQAIPVGGRYAF
                     RDMGTLSWSCVVASDHPLASMPGPLSDDTLRNWPSLVREDTSRTLPKRITWLLDNQKR
                     VVVPDWESSATCLSAGLCVGMVPTHFARQWIDSGKWVALTLENPFPDAACCVTWQQNE
                     ASPALAWLLDYLGDSETLNREWLREPEEAPDSGD"
     gene            complement(7391..8416)
                     /gene="purR"
                     /locus_tag="OPV72_000467"
     CDS             complement(7391..8416)
                     /gene="purR"
                     /locus_tag="OPV72_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional repressor PurR"
                     /protein_id="HCR9912860.1"
                     /translation="MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELH
                     YSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLE
                     KQRAYLSMMAQKRVDGLLVMCSEYPEPLLSMLEEYRHIPMVVMDWGEAKADFTDTVID
                     NAFAGGYMAGRYLVERGHRDIGVIPGPLERNTGAGRLAGFMKAMEEALINVPDNWIVQ
                     GDFEPESGYHAMQQILSQSHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSVIGYDN
                     VRNARFFTPALTTIHQPKDSLGETAFNMLLDRIVNKREESQSIEVHPRLVERRSVADG
                     PFRDYRR"
     gene            8712..8801
                     /locus_tag="OPV72_000468"
     CDS             8712..8801
                     /locus_tag="OPV72_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnhF family membrane protein"
                     /protein_id="HCR9912861.1"
                     /translation="MSTDLKFSLITTLIVLGVIVAGGLTAALH"
     gene            complement(8884..9465)
                     /gene="sodB"
                     /locus_tag="OPV72_000469"
     CDS             complement(8884..9465)
                     /gene="sodB"
                     /locus_tag="OPV72_000469"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase [Fe]"
                     /protein_id="HCR9912862.1"
                     /translation="MSFELPALPYAKDALAPHISAETLEYHYGKHHQTYVTNLNNLIK
                     GTAFEGKSLEEIVRTSEGGIFNNAAQVWNHTFYWNCLAPNAGGEPTGKLADAIAASFG
                     SFAEFKAQFTDAAIKNFGSGWTWLVKSADGKLAIVSTSNAGTPLTTDATPLLTVDVWE
                     HAYYIDYRNARPNYLEHFWALVNWEFVAKNLAA"
     gene            complement(9592..10413)
                     /locus_tag="OPV72_000470"
     CDS             complement(9592..10413)
                     /locus_tag="OPV72_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HCR9912863.1"
                     /translation="MARINKISITLCALLFTTLPFTPMAHASRQAKATPAVSHVTKTA
                     DKKKSTTKKISKTSKKNVKKTSKTSRSSSASTPKRTTAATKSRHTTHRRNRTAPTSIA
                     ALDVTEKCTTRKGRKPHCVKGKGTLPVSIADAHRAKVQKATKTAMSKLMNQIGKPYHW
                     GGASPRTGFDCSGLVYYAYKDLVKIRIPRTANEMYHLRDAAPIERSELKNGDLVFFRT
                     QGRGTADHVGVYVGNGKFIQSPRSGQEIKITSLNEEYWQRHYVGARRVMTPKTIR"
     gene            10748..11095
                     /gene="grxD"
                     /locus_tag="OPV72_000471"
     CDS             10748..11095
                     /gene="grxD"
                     /locus_tag="OPV72_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monothiol glutaredoxin 4"
                     /protein_id="HCR9912864.1"
                     /translation="MSTTIEKIQRQIAENPILLYMKGSPKLPSCGFSAQAVQALSACG
                     ERFAYVDILQNPDIRAELPKYANWPTFPQLWVDGELVGGCDIVIEMYQRGELQQLIKE
                     TAAKYKTQEPDAE"
     gene            complement(11173..11820)
                     /gene="rnt"
                     /locus_tag="OPV72_000472"
     CDS             complement(11173..11820)
                     /gene="rnt"
                     /locus_tag="OPV72_000472"
                     /EC_number="3.1.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease T"
                     /protein_id="HCR9912865.1"
                     /translation="MSDNAQLSGLCDRFRGFYPVVIDVETAGFNAKTDALLEIAAITL
                     KMDEQGWLMPDMTLHFHVEPFAGANLQPEALAFNGIDPSNPLRGAVSEYEALHAIFKM
                     VRKGIKDSGCSRAIMVAHNATFDHSFMMAAAERASLKRNPFHPFVTFDTAALSGLALG
                     QTVLSKACLAAGMEFDGEKAHSALYDTERTAVLFCEIVNRWKRLGGWPLPLPTDK"
     gene            complement(11921..12328)
                     /gene="gloA"
                     /locus_tag="OPV72_000473"
     CDS             complement(11921..12328)
                     /gene="gloA"
                     /locus_tag="OPV72_000473"
                     /EC_number="4.4.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008500591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HCR9912866.1"
                     /translation="MRLLHTMLRVGDLQRSIAFYTNVLGMKLLRTSENPEYKYSLAFV
                     GYGPETEEAVIELTYNWGVESYDMGNAYGHIALSVDNAAEACERIRQNGGNVTREAGP
                     VKGGSTIIAFVEDPDGYKIELIEAKDAGRGLGN"
     gene            complement(12397..13494)
                     /locus_tag="OPV72_000474"
     CDS             complement(12397..13494)
                     /locus_tag="OPV72_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkene reductase"
                     /protein_id="HCR9912867.1"
                     /translation="MSSAKLFTPLKVGAITATNRVFMAPLTRLRSIEPGDIPTPLMAE
                     YYRQRASAGLIISEATQISAQAKGYAGAPGLHSDEQIAAWKKITQGVHAQGGHMAVQL
                     WHTGRISHASLQPGGQAPVAPSAINAGTRTSLRDENGQAIRVETSTPRALDTHEIPGI
                     VNDFRQAIANAREAGFDLVELHSAHGYLLHQFLSPSSNHRTDRYGGSVENRARLVLEV
                     VDAGIKEWGADRIGIRLSPVGTFQNVDNGPNEEADALYLIEALGKRGIAYLHMSEPDW
                     AGGEPYSDAFREKVRARFHGPIIGAGAYTPEKAEDLIEKGLIDAVAFGRDYIANPDLV
                     ARLQRKAELNPQRPESFYGGGAEGYTDYPTL"
     gene            complement(13553..14152)
                     /locus_tag="OPV72_000475"
     CDS             complement(13553..14152)
                     /locus_tag="OPV72_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCR9912868.1"
                     /translation="MNKQTEHDTREHLLATGEQLCMQRGFTGMGLSELLKTAQVPKGS
                     FYHYFRSKEAFGVAMLERHYACYHQRLTAHFTSGPGNHRDRLLAWYQETLKQFCQQGA
                     ISGCLTVKLSAEVCDLSEDMRSTMDKGAQEIMALLARALEDGRNSHCLHFTGQPLPQA
                     QVLYALWLGANLQAKISRSAAPLENALAHVKTIIATPEQ"
     gene            14255..14494
                     /locus_tag="OPV72_000476"
     CDS             14255..14494
                     /locus_tag="OPV72_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1289 domain-containing protein"
                     /protein_id="HCR9912869.1"
                     /translation="MAEQLEFFPVASPCRGICQSDERGFCRGCMRSRDERFNWQKMSD
                     AEKQNVLRLCRQRFLRKIRANKPLPSEDPQQPSLF"
     gene            14545..15441
                     /locus_tag="OPV72_000477"
     CDS             14545..15441
                     /locus_tag="OPV72_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HCR9912870.1"
                     /translation="MVQRVTIAPQGPEFSRFVMGYWRLMDWNMSARQLVSFIEEHLDL
                     GVTTVDHADIYGGYQCEAAFGEALTLAPHLREKLQIVTKCGIATTARAENRLGHYITD
                     RRHIILSAEQSLKDLATDYLDMLLIHRPDPLMDADDVAEAFQHLHQSGKVRHFGVSNF
                     TPAQFTLLQSRLPFTLATNQVEISPVHQPLLLDGTLDQLQQLRIRPMAWSCLGGGRLF
                     NDEAYQPLRQELSVIAQELNASSIEQVVYAWILRLPSQPLPIIGSGKIERVRAALEAE
                     TLSLSRQQWFRIRKAALGYDVP"
     gene            15521..16042
                     /gene="sodC"
                     /locus_tag="OPV72_000478"
     CDS             15521..16042
                     /gene="sodC"
                     /locus_tag="OPV72_000478"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase [Cu-Zn] SodC2"
                     /protein_id="HCR9912871.1"
                     /translation="MKRLSLAMVTLLACAGAQAASEKVEMNLVTAQGVGQSIGTVVID
                     ETEGGLKFTPHLKALPPGEHGFHIHAKGSCQPAIKDGKAVAAEAAGGHLDPQNTGKHE
                     GPEGQGHLGDLPVLVVNNDGIATEPVTAPRLKSLDEVKDKALMIHVGGDNMSDQPKPL
                     GGGGTRYACGVIK"
     gene            complement(16018..18057)
                     /locus_tag="OPV72_000479"
     CDS             complement(16018..18057)
                     /locus_tag="OPV72_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HCR9912872.1"
                     /translation="MKLSLPALRNTPWFKATSGQWRYALRNTIAMCLALTFAYYLNLD
                     EPYWAMTSAAVVSFPTVGGVISKSLGRIAGSLLGATAALIIAGHTLNEPWLFLFSMAA
                     WIGFCTWACAHFTNNAAYAFQLSGYTAAIIAFPMVNIVEITQLWDIAQARVCEVIVGI
                     LCGGMMMMILPSTSDGTALLTALKNMHARLLEHASLLWQPETTDAIRSAHEGVIGQIL
                     TMNLLRIQAFWSHYRFRRQNALLNALLHQQLRLTSVISSLRRMLLNWPTPPENSREVI
                     EQLLAELAKPRADSYTVARIIAPLCPQDEQDYRHLAFWQRLRYFCQLYLRSSRQLYLI
                     ESGAPVDQIHIRRTPGLARHTDNAEAIWSGVRTFCTLTVIGAWSIGVQWESGPGALTL
                     AAISCVLYSIVATPFKSLSLLMRTLVLLSLFSFVVKFGLMVQITDLWQFLLFLFPLFV
                     TMQLLKLQMPKLAGLWGQLIVFMGSFIAVTNPPVYDFADFLNDNTAKIVGVAISWLAF
                     AILRPGSDAVKSRRHIRALRRDFVDQLSRHPSHSESEFESLTYHHVSQLSNSQDALAR
                     RWLLRWGVVLLNCSHVVWQLRAWESRSDPLSRVRDICISLLRDVMSERDVQQRPLAVT
                     LQELQRICDTLAHHHQPAAHELAAIIWRLHCSLSQLEQAPAQGTLSPGYLMTPQA"
     gene            complement(18057..18917)
                     /locus_tag="OPV72_000480"
     CDS             complement(18057..18917)
                     /locus_tag="OPV72_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012218841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HCR9912873.1"
                     /translation="MSLKTIKYFSTLIVAVVAVLAAWWLWNYYMQSPWTRDGKIRAEQ
                     VSVTPQVSGSITQLNIKDNQFVNAGDVLFVIDKTPFHIAELNAQAQLAKAQSDLAKAN
                     NEADRRRHLSRNYISAEDLDSANLNVKAMQASVDVALATLKQAQWQLSQTEVKAPVSG
                     WVTNLSTRTGDYASTGKPLFALVDSHSFYVMGYFEETKLRHIREGEPALITLYSGNVK
                     LQGHVGSIGRAIYDQSVESDSGLVPDIKPNVPWVRLAQRVPVRIEFDALPQDITLVSG
                     TTCSVAIGQR"
     gene            complement(18920..19156)
                     /locus_tag="OPV72_000481"
     CDS             complement(18920..19156)
                     /locus_tag="OPV72_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1656 domain-containing protein"
                     /protein_id="HCR9912874.1"
                     /translation="MKCILNATGLPLQDLMLGASVYFPPFFKAFALGFVIWLFIHRLL
                     RDRIYSDEIWHPLLMDLSLFTLCVCLGLVLLIVW"
     gene            19351..19791
                     /gene="slyA"
                     /locus_tag="OPV72_000482"
     CDS             19351..19791
                     /gene="slyA"
                     /locus_tag="OPV72_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460407.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SlyA"
                     /protein_id="HCR9912875.1"
                     /translation="MKLESPLGSDLARLVRIWRALIDHRLKPLELTQTHWVTLHNIHQ
                     LPPDQSQIQLAKAIGIEQPSLVRTLDQLEDKGLISRQTCASDRRAKRIKLTEKAEPLI
                     AEMEEVIHKTRGEILAGISSEEIELLIKLVAKLEHNIMELHSHD"
     gene            complement(19839..20306)
                     /gene="slyB"
                     /locus_tag="OPV72_000483"
     CDS             complement(19839..20306)
                     /gene="slyB"
                     /locus_tag="OPV72_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipoprotein SlyB"
                     /protein_id="HCR9912876.1"
                     /translation="MIKRVLAVSLMGLSLAGCVNNDSLSGDVYTASEAKQVQNVTYGT
                     IVNVRPVQIQGGDDSNVIGAIGGAVLGGFLGNTIGGGTGRSLATAAGAVAGGVAGQGV
                     QSAMNKTQGVELEIRKDDGNTIMVVQKQGNTRFSAGQRVVLASNGSQVTVSPR"
     gene            20579..21700
                     /gene="anmK"
                     /locus_tag="OPV72_000484"
     CDS             20579..21700
                     /gene="anmK"
                     /locus_tag="OPV72_000484"
                     /EC_number="2.7.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anhydro-N-acetylmuramic acid kinase"
                     /protein_id="HCR9912877.1"
                     /translation="MKSGRFIGVMSGTSLDGVDVVLAAIDETMVAQQASLTWPIPVHL
                     KKGILDICQGQPLTLSQLGQLDTQLGRLFAQAVNALLAQQRLQPRDIVAIGCHGQTVW
                     HEPTGEAPHTLQIGDNNHIVAHTGITVVGDFRRRDIALGGQGAPLVPAFHHALLGHPT
                     EKRMVLNIGGIANLSLLFPGQAVRGYDTGPGNMLMDAWIWRQCAQPYDKDAAWAKEGQ
                     VILPLLQKMLRDPYFAASAPKSTGREYFNYGWLERHLTAFPGADARDVQATLAELTAV
                     SIAQQVLLNGGCERLMVCGGGSRNPLVMARLAALLPGIEVSTTDKAGISGDDMEALAF
                     AWLAWRTLAGLPGNLPSVTGATEASVLGAIYPANPITQS"
     gene            21788..22117
                     /gene="mliC"
                     /locus_tag="OPV72_000485"
                     /pseudo
     CDS             21788..22117
                     /gene="mliC"
                     /locus_tag="OPV72_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460410.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="C-type lysozyme inhibitor"
     gene            22176..22832
                     /gene="pdxH"
                     /locus_tag="OPV72_000486"
     CDS             22176..22832
                     /gene="pdxH"
                     /locus_tag="OPV72_000486"
                     /EC_number="1.4.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase"
                     /protein_id="HCR9912878.1"
                     /translation="MSDNNQLQQIAHLRREYTKGGLRRRDLPAEPLTLFERWLGQACD
                     ARLADPTAMVVATVDDKGQPYQRIVLLKHYDEKGLVFYTNLGSRKAHQIEHNPRISLL
                     FPWHMLERQVMVTGKAERLSTLEVVRYFHSRPRDSQIGAWVSKQSSRISARGILESKF
                     LELKQKFQQGEVPLPSFWGGFRVSIEQMEFWQGGEHRLHDRFLYQRDDGAWKIDRLAP
                     "
     gene            22959..24233
                     /gene="tyrS"
                     /locus_tag="OPV72_000487"
     CDS             22959..24233
                     /gene="tyrS"
                     /locus_tag="OPV72_000487"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HCR9912879.1"
                     /translation="MASSNLIKQLQERGLVAQVTDEDALAERLAQGPIALYCGFDPTA
                     DSLHLGHLVPLLCLKRFQQAGHKPVALVGGATGLIGDPSFKAAERKLNTEETVQEWVA
                     KIRKQVAPFLDFDCGENSAIAANNYDWFGSMNVLTFLRDIGKHFSVNQMINKEAVKQR
                     LNRDDQGISFTEFSYNLLQGYDFACLNKLHGVALQIGGSDQWGNITSGIDLTRRLHQN
                     QVFGLTVPLITKADGTKFGKTEGGAVWLDPKKTSPYKFYQFWINTADADVYRFLKFFT
                     FMDIEEINALEEEDKNSGKAPRAQYVLAEQVTRLVHGEEGLVAAKRITECLFSGSLSA
                     LSEADFEQLAQDGVPMVEMEKGADLMQALVDAELQPSRGQARKTIASNAVTINGEKQS
                     DPEYIFNDEDRLFGRYTLLRRGKKNYCLICWK"
     gene            24293..24952
                     /gene="pdxY"
                     /locus_tag="OPV72_000488"
                     /pseudo
     CDS             24293..24952
                     /gene="pdxY"
                     /locus_tag="OPV72_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460413.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal kinase PdxY"
     gene            complement(24982..25587)
                     /gene="gstA"
                     /locus_tag="OPV72_000489"
     CDS             complement(24982..25587)
                     /gene="gstA"
                     /locus_tag="OPV72_000489"
                     /EC_number="2.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione transferase GstA"
                     /protein_id="HCR9912880.1"
                     /translation="MKLFYKPGACSLASHIILREIGKDFTLDGVDLAKKRLENGDDYL
                     AVNPKGQVPALLLDDGTLLTEGVAIMQYLADSVPDRQLLAPVSSLARYHTLEWLNYIA
                     TELHKGFTPLFRPDTPETLKPAVRAGLEKKFQYVDESLSDDQWICGQRFTIADAYLFT
                     VLRWAYGVKLNMDGSTHIESYMQRVAKRPTVAAALKAEGLN"
     gene            complement(25692..27197)
                     /gene="dtpA"
                     /locus_tag="OPV72_000490"
     CDS             complement(25692..27197)
                     /gene="dtpA"
                     /locus_tag="OPV72_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide/tripeptide permease DtpA"
                     /protein_id="HCR9912881.1"
                     /translation="MSTANKKPTESVSLNAFKQPKAFYLIFSIELWERFGYYGLQGIM
                     AVYLVKQLGMSEADSITLFSSFSALVYGLVAIGGWLGDKILGTKRVIMLGAVVLAIGY
                     ALVAWSGHDAGIVYMGMAAIAVGNGLFKANPSSLLSTCYAKDDPRLDGAFTMYYMSVN
                     IGSFFSMLATPWLAARYGWSTAFALSVVGMLITVVNFAFCQRWVKSYGSKPDFEPINF
                     RNLLLTIVGIVVLIAVATWLLHNQDIARMVLGVIALGIVIIFGKEAFSMHGAARRKMI
                     VAFILMLQAIIFFVLYSQMPTSLNFFAIRNVEHSILGIAFEPEQYQALNPFWIITGSP
                     ILAAIYNRMGDTLPMPMKFAIGMVLCSGAFLILPLGAKFANDAGIVSVNWLIASYGLQ
                     SIGELMISGLGLAMVAQLVPQRLMGFIMGSWFLTTAGANIIGGYVANLMAVPSDVTDP
                     LMSLEVYGRVFMQIGIATAVIAVLMLLTAPKLNRMTQDDDTAEKGSKAATV"
     gene            complement(27798..28433)
                     /gene="nth"
                     /locus_tag="OPV72_000491"
     CDS             complement(27798..28433)
                     /gene="nth"
                     /locus_tag="OPV72_000491"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HCR9912882.1"
                     /translation="MNKAKRLEILTRLRDSNPHPTTELNFTSPFELLIAVLLSAQATD
                     VSVNKATAKLYPAANTPAAMLELGVEGVKSYIKTIGLFNSKAENVIKTCRILMDKHNG
                     EVPEDRAALEALPGVGRKTANVVLNTAFGWPTIAVDTHIFRVCNRTQFAPGKNVEQVE
                     EKLLKVVPNEFKVDCHHWLILHGRYTCIARKPRCGSCLIEDLCEYKEKVDI"
     gene            complement(28433..29125)
                     /locus_tag="OPV72_000492"
     CDS             complement(28433..29125)
                     /locus_tag="OPV72_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit E"
                     /protein_id="HCR9912883.1"
                     /translation="MSEIKDIVVQGLWKNNSALVQLLGLCPLLAVTSTATNALGLGLA
                     TTLVLTLTNLTVSALRRWTPAEIRIPIYVMIIASVVSAVQMLINAYAFGLYQSLGIFI
                     PLIVTNCIVVGRAEAFAAKKGPWLSALDGFSIGMGATGAMFVLGSLREILGNGTLFDG
                     ADSLLGGWAKVLRVEIFHTDSPFLLAMLPPGAFIGLGLMLAVKYLIDEKMKKRRAETA
                     PSAVPAGETGKV"
     gene            complement(29128..29748)
                     /gene="rsxG"
                     /locus_tag="OPV72_000493"
     CDS             complement(29128..29748)
                     /gene="rsxG"
                     /locus_tag="OPV72_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxG"
                     /protein_id="HCR9912884.1"
                     /translation="MLKTIRKHGITLALFAAGSTGLTAVINQMTKSTIHEQALQQQHA
                     LFDQVLPPDRYNNNLQESCYLVDAPALGKGTHRVFIARKDDKPVAAIIEATAPDGYSG
                     AIQLIVGADFNGTILGTRVTEHHETPGLGDKIERRLSDWITHFSGKTISGENDTHWAV
                     KKDGGDFDQFTGATITPRAVVNAVKRAGLYAESLPAQLPHLTACGE"
     gene            complement(29752..30810)
                     /gene="rsxD"
                     /locus_tag="OPV72_000494"
     CDS             complement(29752..30810)
                     /gene="rsxD"
                     /locus_tag="OPV72_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxD"
                     /protein_id="HCR9912885.1"
                     /translation="MVFRIASSPYTHNQRQTSRIMLLVLIAALPGIAAQTWFFGWGTL
                     FQIVLAAITALVAEAIVLRLRKQSVASHLQDYSALLTGLLLAVSIPPLAPWWMVVLGT
                     GFAIIIAKQLYGGLGQNPFNPAMIGYVVLLISFPVQMTSWLPPYEIAATTPDILDTLR
                     MIFSGHTASGGDMTLLRIGIDGISQATPLDTFKTSLRAGHSVEQIMQYPIYSGALAGV
                     GWQWVNLAWLVGGVFLLWQKAIRWHIPVSFLLTLALCAALGWLFSPATLASPQLHLLS
                     GATMLGAFFILTDPVTASTTNRGRLIFGALAGVLVWLIRSFGGYPDGVAFAVLLANIT
                     VPLIDYYTRPRVYGHRKG"
     gene            complement(30811..32832)
                     /gene="rsxC"
                     /locus_tag="OPV72_000495"
     CDS             complement(30811..32832)
                     /gene="rsxC"
                     /locus_tag="OPV72_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxC"
                     /protein_id="HCR9912886.1"
                     /translation="MLKLFSAFRKDKIWDFDGGIHPPEMKSQSNGTPLRQVPLAPRFV
                     IPLKQHIGAEGELCVSVGDRVLRGQALTRGRGRMLPVHAPTSGTVIAIAPHSTAHPSA
                     LAELSVIIDADGEDRWIEREGWSDYRAHSREALIERIHQYGVAGLGGAGFPTGVKLQG
                     GDDKITTLIINAAECEPYITADDRLMQDCAAQIVEGIRILAHILQPREVLIGIEDNKP
                     QAISMLRAVLADAHDISLRVIPTKYPSGGAKQLTQILTGKQVPHGGRSSDIGVLMQNV
                     GTAYAVKRAVVDGEPITERVVTLTGEAISRPGNVWARLGTPVRHLLNDAGFCPSADQM
                     VIMGGPLMGFTLPWLDVPVVKITNCLLAPSVTEMGAPQEEKSCIRCSACADACPADLL
                     PQQLYWFSKGQQHDKATAHHIADCIECGACAWVCPSNIPLVQYFRQEKAEINAIRLEE
                     KRAAEAKARFEARQARLEREKAARLARHKSAAVQPAAKDQDAIAAALARVKEKQAQAT
                     QPVVIQAGSLPDNSAVIAAREARKAQARAKQAAHPMADSAISGDDPRKAAVEAAIARA
                     KARKQEQQAGSEPAEPVDPRKAAVEAAIARAKARKQEQQAGSEPAEPVDPRKAAVEAA
                     IARAKARKQEQQTVSEPVEPADPRKAAVAAAIARVQAKKAAQQQVVNED"
     gene            complement(32825..33403)
                     /gene="rsxB"
                     /locus_tag="OPV72_000496"
     CDS             complement(32825..33403)
                     /gene="rsxB"
                     /locus_tag="OPV72_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxB"
                     /protein_id="HCR9912887.1"
                     /translation="MNTIWIAVGALTLLGLVFGAILGYASRRFAVEDDPVVEKIDAIL
                     PQSQCGQCGYPGCRPYAEAVGLQGEKINRCAPGGEAVMLKMAELLNVEPQPCDGEEQQ
                     AAPVRMLAVIDENNCIGCTKCIQACPVDAIVGATRAMHTVMSDLCTGCNLCVDPCPTH
                     CIELRPVNETPDSWKWDLNTIPVRIIPVEQHA"
     gene            complement(33403..33984)
                     /gene="rsxA"
                     /locus_tag="OPV72_000497"
     CDS             complement(33403..33984)
                     /gene="rsxA"
                     /locus_tag="OPV72_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017456621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxA"
                     /protein_id="HCR9912888.1"
                     /translation="MTDYLLLFVGTVLVNNFVLVKFLGLCPFMGVSKKLETAMGMGLA
                     TTFVMTLASICAWLIDTWILIPLDLIYLRTLAFILVIAVVVQFTEMVVRKTSPALYRL
                     LGIFLPLITTNCAVLGVALLNINLGHHFLQSALYGFSAAVGFSLVMVLFAAIRERLAV
                     ADVPAPFRGNAIALITAGLMSLAFMGFSGLVKL"
     gene            complement(34061..34501)
                     /locus_tag="OPV72_000498"
     CDS             complement(34061..34501)
                     /locus_tag="OPV72_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2569 domain-containing protein"
                     /protein_id="HCR9912889.1"
                     /translation="MTTTPPQRIGGWLLGPLAWLLVALLSASLALLLYVMALATPQTF
                     KTLSGQETGNLLLWGISFITAIAMWYYTLWLTIAFFKRRRCVPKHYIIWLLVSVLLAV
                     KAFAFSPVSDAFAVRQLLFPLLATALIVPYLKRSARVKTTFVNP"
     gene            complement(34590..34805)
                     /gene="ydgT"
                     /locus_tag="OPV72_000499"
     CDS             complement(34590..34805)
                     /gene="ydgT"
                     /locus_tag="OPV72_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460424.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription modulator YdgT"
                     /protein_id="HCR9912890.1"
                     /translation="MTVQDYLLKFRKISSLESLEKLFDHLNYTLTDDMDIVNMYRAAD
                     HRRAELVSGGRLFDVGQVPQSVWRYVQ"
     gene            complement(35104..35229)
                     /gene="blr"
                     /locus_tag="OPV72_000500"
     CDS             complement(35104..35229)
                     /gene="blr"
                     /locus_tag="OPV72_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division septum protein Blr"
                     /protein_id="HCR9912891.1"
                     /translation="MNRLIELTGWIVLIISVILLGIANHIDNYQPPEPTASVQKK"
     gene            35437..36477
                     /locus_tag="OPV72_000501"
     CDS             35437..36477
                     /locus_tag="OPV72_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310359.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HCR9912892.1"
                     /translation="MNDKIRVGLIGYGYASKTFHAPLIMGTPGLELAAVSSSDETKVK
                     ADWPAVSVVSEPRHLFNDPHIDLIVIPTPNDTHFPLAKAALEAGKHVVVDKPFTVTLS
                     QARELDALARSTGRVLSVFHNRRWDSDFLTLKALLADGVLGEVSLFESHFDRFRPQVR
                     DRWREQGGPGSGIWYDLAPHLLDQAIQLFGLPVSMTVDLAQLRPGAQSTDYFHAILSY
                     PQRRVILHGTMLAAAESARYIVHGSRGSYVKYGLDPQEERLKNGERLPQEDWGYDMRD
                     GVLTLVEGETRKEENWLTLPGNYPAYYAAIRDALNGNGENPVPASQAIQIMELIELGM
                     ESAKHRATLCLA"
     gene            complement(36551..37552)
                     /gene="add"
                     /locus_tag="OPV72_000502"
     CDS             complement(36551..37552)
                     /gene="add"
                     /locus_tag="OPV72_000502"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HCR9912893.1"
                     /translation="MIDITLPLTDIHRHLDGNIRAQTILDLGRQFNIALPAQTLETLI
                     PHVQVTSTEPDLVSFLTKLDWGVKVLASLDACRRVAFENIEDAARNGLHYVELRFSPG
                     YMAMAHQLPIAGVVEAVIDGVRDGCNTFGVEARLIGIMSRTFGEAACLQELDALLAHR
                     EKITALDLAGDELGFPGSLFLSHFNRARDAGWHITVHAGEAAGPESIWQTIRELGAER
                     IGHGVKAVEDRALMDFLAQQRIGIESCLTSNIQTSTVASLADHPLKTFLEHGVLASLN
                     TDDPAVQGVDIIHEYHVAAPAAGLSREQIRQAQINGLEIAFLSDSEKRALREKVAAA"
     gene            complement(37778..37909)
                     /locus_tag="OPV72_000503"
                     /pseudo
     CDS             complement(37778..37909)
                     /locus_tag="OPV72_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000459379.1"
                     /note="catalyzes the formation of homocysteine and
                     pyruvate from cystathionine; also acts a a negative
                     regulator for the mal regulon but interacting with the
                     transcriptional activator MalT; internal stop; incomplete;
                     partial in the middle of a contig; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            complement(37919..38139)
                     /locus_tag="OPV72_000504"
                     /pseudo
     CDS             complement(37919..38139)
                     /locus_tag="OPV72_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310356.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIB"
     gene            complement(38258..39766)
                     /locus_tag="OPV72_000505"
     CDS             complement(38258..39766)
                     /locus_tag="OPV72_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdgA family protein"
                     /protein_id="HCR9912894.1"
                     /translation="MKKTLVAAGVVIALGIVWTGGAWYTGKKLENHLAEMVTQANEQL
                     KRTAPEAGVELSYQNYQRGVFSSHLQLVVKPVAGADNTWLKPGQSIVLDESVSHGPFP
                     LAQLKTLNLIPSMASVKTTLVNNDAAKPLFDIAKGDAPFVINTRIGYGGDTRSDISLK
                     PLNYENAGEKVAFSGGEFQLNADKDGNVVSLSGEAQSGLVDAVNEYNQKVQLTFNNLK
                     TDGTSKLASFGERVGDQKLTLDKLSIAIEGKEMAVLEGMEIAGKSDLVNDGKTINSQL
                     DYSLNSLKVQNQDLGSGKLTLKVGQIDGEAWHQFSQQYHAQTQALLNQPDVAQNPELY
                     QQKVTEAFFSALPVLLKGDPVLTLAPLSWKNAKGETTLNLSLFLKDPATTTAQPQTLA
                     QEVDRSVKSLDAKLAIPMDMAVEFMTQIAKLEGYQQDDAEKLAKQQVQGLSAMGQMFR
                     LTTLKDNTIASSLQYANGQITLNGQKMPLEDFVGLFGMPALSVPDVPALPQQ"
     gene            complement(39869..41044)
                     /gene="manA"
                     /locus_tag="OPV72_000506"
     CDS             complement(39869..41044)
                     /gene="manA"
                     /locus_tag="OPV72_000506"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase"
                     /protein_id="HCR9912895.1"
                     /translation="MQKLINSVQNYAWGSKTALTELYGIANPQQQPMAELWMGAHPKS
                     SSRITTANGETVSLRDAIEKNKTAMLGEAVANRFGELPFLFKVLCAAQPLSIQVHPNK
                     RNSEIGFAKENAAGIPMDAAERNYKDPNHKPELVFALAPFLAMNAFREFSDIVSLLQP
                     VAGAHSAIAHFLQAPNAERLSQLFASLLNMQGEEKSRALAVLKAALNSQQGEPWQTIR
                     VISEYYPDDSGLFSPLLLNVVKLNPGEAMFLFAETPHAYLQGVALEVMANSDNVLRAG
                     LTPKYIDIPELVANVKFEPKPAGELLTAPVKSGAELDFPIPVDDFAFSLHDLALQETS
                     IGQHSAAILFCVEGEAVLRKDEQRLVLKPGESAFIGADESPVNASGTGRLARVYNKL"
     gene            41244..42890
                     /gene="fumB"
                     /locus_tag="OPV72_000507"
     CDS             41244..42890
                     /gene="fumB"
                     /locus_tag="OPV72_000507"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000066594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I fumarate hydratase"
                     /protein_id="HCR9912896.1"
                     /translation="MSNKPFFYQDPFPLKKDDTEYYLLTSEHVSVAEFEGQEILKVAP
                     EALTLLARQAFHDASFMLRPAHQQQVADILRDPQASENDKYVALQFLRNSDIAAKGVL
                     PTCQDTGTAIIVGKKGQRVWTGGGDEAALARGVYNTYIEDNLRYSQNAALDMYKEVNT
                     GTNLPAQIDLYSVDGDEYKFLCIAKGGGSANKTYLYQETKALLTPGKLKNYLVDKMRT
                     LGTAACPPYHIAFVIGGTSAEANLKTVKLASAKYYDALPTEGNEHGQAFRDIELEKEL
                     LLEAQNLGLGAQFGGKYFAHDIRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGFW
                     IEKLERNPGKYIPEALRQAGEGEAVRVDLNRPMSEILQQLSQYPVSTRLSLNGTIIVG
                     RDIAHAKLKERMDRGEGLPQYIKDHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQ
                     LQSQGGSMIMLAKGNRSQQVTDACKKHGGFYLGSIGGPAAVLAQGSIKRLECVEYPEL
                     GMEAIWKIEVEDFPAFILVDDKGNDFFQQIQSSQCARCVK"
     gene            43058..44461
                     /gene="fumC"
                     /locus_tag="OPV72_000508"
     CDS             43058..44461
                     /gene="fumC"
                     /locus_tag="OPV72_000508"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fumarate hydratase"
                     /protein_id="HCR9912897.1"
                     /translation="MVTVRREKDSMGVIEVPADKLWGAQTQRSLEHFRISTEKMPVSL
                     IHALALTKRAAAKVNQDLGLLAAEKASAIIEAADEVLAGKHADEFPLAIWQTGSGTQS
                     NMNMNEVLANRASEILGGVRGMERKVHPNDDVNKSQSSNDVFPTAMHVAALLALREHL
                     IPQLSALTDTLRDKSHAFADIVKIGRTHLQDATPLTLGQEISGWVAMLEHNLRHIEHS
                     LPHVAELALGGTAVGTGLNTHPEYARRVAEELATITAAPFVTAPNKFEALATCDALVQ
                     AHGALKGLAASLMKIANDVRWLASGPRCGIGEIAIPENEPGSSIMPGKVNPTQCEAVT
                     MLCCQVMGNDVAINMGGASGNFELNVYRPMVIHNFLQTVRLLADGMASFNQHCASGIE
                     PNRERITQLLNESLMLVTALNTHIGYDKAAEIAKKAHKEGLTLKASAVALGYLSDAEF
                     DAWVRPELMVGSMTPGR"
     gene            complement(44458..45387)
                     /locus_tag="OPV72_000509"
     CDS             complement(44458..45387)
                     /locus_tag="OPV72_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication terminus site-binding protein"
                     /protein_id="HCR9912898.1"
                     /translation="MSRYDLVERLNGTFRQIEQHLAALSDNLQQHSLLIASVFSLPQV
                     TKEAEHAPLDTIEVTQHLGKEAEALALRHYRHLFIQQQSENRSSKAAVRLPGVLCYQV
                     DNATQLDLENQVQRINQLKTTFEQMVTVESGLPSAARFEWVHRHLPGLITLNAYRTLT
                     LINNPATIRFGWANKHIIKNLSRDEVLSQLKKSLASPRSVPPWTREQWQFKLEREYQD
                     IAALPQQAKLKIKRPVKVQPIARIWYKGQQKQVQHACPSPIIALINTDNGAGVPDIGG
                     LENYDADNIQHRFKPQAQPLRLIIPRLHLYVAD"
     gene            complement(45463..46764)
                     /gene="rstB"
                     /locus_tag="OPV72_000510"
     CDS             complement(45463..46764)
                     /gene="rstB"
                     /locus_tag="OPV72_000510"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     RstB"
                     /protein_id="HCR9912899.1"
                     /translation="MKKLFVQFYLLLFVCFLVMTLLVGLVYKFTAERAGRQSLDDLMK
                     SSLYLMRSELREIPPREWGKTLKEMDLNLSFDLRVEPLNHYKLDAATTQRLREGDIVA
                     LDDQYTFIQRIPRSHYVLAVGPVPYLYFLHQMRLLDIALMALIAFSLAFPVFIWMRPH
                     WQEMLRLESAAQRFGEGHLTERLHFDNGSSFERLGVAFNQMADNINALIASKKQLIDG
                     IAHELRTPLVRLRYRLEMSENLTPPESQALNRDIGQLEALIEELLTYARLDRPQNELM
                     LTKPDLPAWLFAHLQDVQSVNPERAVNLLTCVIGDYGALDMRLMSRVLDNLLNNALRY
                     SRTTVQVSLLLDGSQATLIVEDDGPGIEADARERVFEPFVRLDPSRDRATGGCGLGLA
                     IVHSIALAMGGSVVCDDSELGGAKFSFRWPVWHAMPDMTAA"
     gene            complement(46875..48581)
                     /locus_tag="OPV72_000511"
     CDS             complement(46875..48581)
                     /locus_tag="OPV72_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HCR9912900.1"
                     /translation="MLMISLVPPLLSRTALLFLLTATGAATAARPAADIILHNGNIIT
                     LNDAQPQASALAISGSRIVAIGDDTATNEWRGDHTRTIDLQGKTVIPGLTDTHIHAIR
                     GGQTWTFETYWYDSPSLKDALDKLRADANRRPHDQWVAVVGSWIPAQFAENRASTVAE
                     LSHALPDHPAYIQYLYDYALVNQRGIDVLGLNDTPPPDLAGIRVERDAKGSATGKLFG
                     DIAAFNQLFASISSNADREGGLRQFFADMNARGVTGIIDPSAGPAAAYEPLFAMRNQG
                     DLPLRVGYRIPVQPEAKGHEAQWFSNLMAFRPARADDGQLAFLGLGESLVAGMNDGVR
                     MAPGFSSSEQDKTALRQVATFAAKRGIPLEIHAYTDDSADAILTIFEQVAQQYDLRPL
                     RWSIAHLNTGSPQTLERMRKLGLAYTVQMGPYFEGLAIRDANPPGATDNSPPVRLALD
                     KGLVVAGGTDSTRIGIAGVWHAIEYHITGIASGGSVRKPASERLTRLEALALYTRHAA
                     WLAFAEQHRGQLSVGKQADLAVLNQPFMTMPEDRIDTIRAVLTLVDGRIVHESPDLNA
                     GQ"
     gene            complement(48734..49885)
                     /gene="ompS2"
                     /locus_tag="OPV72_000512"
     CDS             complement(48734..49885)
                     /gene="ompS2"
                     /locus_tag="OPV72_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpS2"
                     /protein_id="HCR9912901.1"
                     /translation="MKRKVLALVIPALLAAGAAHAAEIYNKDGNKLDLYGKVDGLHYF
                     SDDSSKDGDQTYMRVGFKGETQINDQLTGYGQWEYNVQANTTEGEGANSWTRLAFAGL
                     KFGDYGSFDYGRNYGVLYDVEGWTDMLPEFGGDSYTYADNYMTGRANGVATYRNTDFF
                     GLVDGLNFALQYQGKNESQSADDVNIGTNNRNNGDDIRYDNGDGFGISTTYDIGMGFS
                     AGAAYTTSDRTNEQVNAGGTIAGGDKADAWTAGLKYDANNIYLATMYSETRNMTPYGK
                     TDKGYDGGVANKTQNFEVTAQYQFDFGLRPAVSFLMSKGKDLTYNNVNGDDKDLVKYA
                     DVGATYYFNKNFSTYVDYKINLLDDDDPFYKDAGISTDDIVALGMVYQF"
BASE COUNT        12220 a        12806 c        13347 g        11559 t
ORIGIN      
        1 gctgattgcg ctttatttgt attttcattt ctttactgaa aagatgattt tgatactgat
       61 tgagtcaata acgttcacat tacaattagt aaataaacca ttttcttatg cactaacgca
      121 attgagtcat gctttaatag agtcactgac ttctgcactg ctgtttctgg gcgctggggt
      181 aatagttgct actgtgggta gcgtgtttct tcaggtgggg gtggttattg ccagcaaggc
      241 cattggtttt aaaagcgagc atataaatcc ggtaagtaat tttaagcaga tattctcttt
      301 acatagcgta gtagaattat gtaaatccag cctaaaagtt atcatgttat ctcttatctt
      361 tgcctttttc ttttattatt atgccagtac ttttcgggcg ctaccgtact gtgggttagc
      421 ctgtggcgtg cttgtggttt cttctttaat aaaatggtta tgggtagggg tgatggcttt
      481 ttatatcgtc gttggcatac tggactattc ttttcaatat tataagatta gaaaagatct
      541 aaaaatgagt aaagatgacg taaaacagga gcataaagat ctggagggcg atcctcaaat
      601 gaagacacgg cgtcgggaaa tgcagagtga aatacaaagt gggagtttag ctcaatctgt
      661 taaacaatct gttgcggtag tgcgtaatcc aacgcatatt gcggtttgtc ttggctatca
      721 tcccaccgat atgccaatac cacgcgtcct ggaaaaaggc agtgatgctc aagctaacta
      781 tattgttaac atcgctgaac gcaactgcat ccccgttgtt gaaaatgttg agctggcccg
      841 ctcattattt tttgaagtgg aacgcggaga taaaattcct gaaacgttat ttgaacccgt
      901 tgcagccttg ttacgtatgg tgatgaagat agattatgcg cattctaccg aaacaccata
      961 aatgcttttg gtatgcttct tcaggccact gcgaaggtta agagggtaat agcgtataga
     1021 gcagtgcttg acgataaagg tgagagactg aaaataatcg cttttagcct ggcacaagca
     1081 ccagatagcg tattataaaa ttaaacaaga taatggattg gtgcgtctga atggactcga
     1141 accatcgacc cccaccatgt caaggtggtg ctctaaccaa ctgagctaca gacgcattaa
     1201 aatgatggtg cgttcaattg gactcgaacc aacgaccccc accatgtcaa ggtggtgctc
     1261 taaccaactg agctatgaac gcaacgttgt aggtgacaac ggggacgaat attagcgtca
     1321 caaccgcaat gaggcaagag ggaaatcgca attttcttcc tgaaatcacc tgattgcggt
     1381 ggaaatatgc aacatgtcga aaaaatagcc gccatgcgac ggctatcgtc gtattatcgc
     1441 gcagcgcgct gcaaaatgat ggcggacggc tgacgttgta gatagcgcat ccgtagcatc
     1501 attaacaccg ccgccgaggt caggccgatg atgaacccca tccagaagcc tgccggtccc
     1561 atacgatcca ccaccaaatc cgttaacgcc aggatataac cgctgggtaa acctaacacc
     1621 cagtaggcgg taaaggtgat aaaaaagatg gaacgcgtat ctttataacc gcgcagaata
     1681 ccgctgccga taacctgtat agagtcggaa atctggtaaa ccgcagcgag cagcattaat
     1741 tgcgcggcaa gcgccacgac ctcagggttg tcattgtaga gcaaagcaat atgcttacgc
     1801 agagtaacgg taaaaatagc ggtaaccaca gccatacaaa tgccgacgcc taaaccggta
     1861 cgcgctgcgg tttgcgcatc cagcgttgag ccctggccca gacgataacc cactcgaatc
     1921 gttaccgccg cagccagcga catcggcagt acgaacatca gcgagctaaa gttaagcgca
     1981 atctgatgac cggcgacatc cacaatacct aatggcgaaa ccagcagcgc aacgaccgca
     2041 aacaacgtca cttcaaagaa cagcgccagc gcaatcggca accccagttg aatcaggcgc
     2101 ttcatgacga cgctatcagg tttgccaaag cctttttcat tacgaatatc acgcattgaa
     2161 cgcgcgtgtt taatgtaaga aagcatggcg ataaacatca cccaatagac cgccgcagtc
     2221 gcaacgccgc agccgatacc gccgagttcc ggcataccaa aatggccata gataaaaata
     2281 tagttcaccg gaatattcac cagcaggccc aaaaatccca tcaccatacc cggtttggtt
     2341 ttggccagac cttcgcactg gtttcgcgct acctgaaaga aaaggtatcc tggcgcgccc
     2401 cacagcagcg cgcgaagata acccacggct ttatcggcca gcgccggatc aatattatgc
     2461 atagagcgga taatgtatcc ggcattccac aggacgatca tcaccagcac ggagacaaag
     2521 cccgccagcc agaacccttg tcgaacctga tgcgcgatac gctcacgacg gccggagcca
     2581 ttgagttgcg caatcacagg cgtcaaggcc agcagtaagc cgtgaccaaa caaaatggcg
     2641 ggaagccaga tagaggtgcc gatagcgacg gcagccatgt ccgtagcgct atagcctccc
     2701 gccatgacgg tatcgacgaa tcccattgcg gtctgtgcca cttgcgcaag gatcaccggt
     2761 atcgctaacg ctaataactg acgcgcttca ctggtatact tctgcacgta ttcacctttt
     2821 attttgttgt tatatgaaag actaaaaagc cgccgtagtg gcagccaaaa gaaatagcag
     2881 gggaaatttc agtctattgt agcggggtat tactatttct ccagtgaaaa aacagttgtt
     2941 aacggcgcat tgctggcaag ctgtttttcc acctgctatt gtgctgaaca gttctgcgtt
     3001 tatttatttc aggagttgaa gatatgttta cggggatcgt acagggtacc gcgaaactgg
     3061 tatcgattga tgaaaaaccc aactttcgca cccatgtggt gacgttaccg gactacatgc
     3121 tggaggggct ggagacgggg gcgtcggtag cgcataacgg atgctgtttg acggtaactg
     3181 aaataaacgg caatcagata agctttgatc tgatgaaaga aacgttgcgc atcaccaatc
     3241 tgggcgcgtt gagggtaggt gatgaggtca acgtagagcg cgccgccaaa ttcagcgatg
     3301 aaatcggtgg acatctgatg tcggggcata ttattacgac ggcggagatc gcgaaaatcc
     3361 tgacctctga aaataaccat caggtgtggt ttaaagtgca ggatgcgtcc ctgatgaagt
     3421 atatcctgta caagggcttt atcggcgtcg acggcatcag tttgaccgtc ggcgaggtaa
     3481 cgccaacgcg cttctgcgtg catctcattc cggaaacgct ggaacgtact acgcttggca
     3541 gaaaaaaact gggtgagcgt gtgaatatcg agatcgatcc gcaaacgcag gcggttgtcg
     3601 ataccgtaga acgcgtactg gctacacgag aaaatgtggt cagaaatcag gccgacattg
     3661 gctaacggaa aataagattc ccccgcatga aatgcggggg agatgattag cgaggaacgc
     3721 gcagaccgtt ttcaacgccg cgcgtaaata ccacctgcca aagctggata tcacgcgcgc
     3781 gaaacgcacc cgcgcaggcg ttgagataat agctgaacat acgtttaaag cgctcgttat
     3841 aattgcccgc aatctctggc caggcattga taaagcgctc atgccacgcc atcagagtcg
     3901 tgtcatagtc ggcgccaaag ttatgccagt cttccattac aaagtgtgat tcgctggcct
     3961 cggcgatttg acgaacagac ggcaagcaac cgttggggaa aatatactta ttgatccacg
     4021 gatcgacatt atgatcggtt tttttagaac caatagtatg gagcaggaaa agaccatccg
     4081 gttttaaatt cctgtcaaca acttcaaaat aggtgttgta gttttttggc ccgacatgtt
     4141 cgaacatgcc gacggagacg attcggtcaa actgatcgtt aaggtcgcga taatcttcca
     4201 ggagaatgga gacatccaga ccttcgcaac gcgtctgcgc cattttttgt tgttcagcgg
     4261 agatcgttac gcccaccacg ctaacgccat aatgggtcgc catatattgc gacaggccgc
     4321 cccagccgca gccgatatcc agcacacgca tccccggttg tagctgtagc ttttcgcaaa
     4381 ttaatttcag cttggcttgc tgtgccgctt ccagcgtatc ggcatctttc cagtaggcgc
     4441 aagaatattg catataggga tcgagcatac gggaaaaaag gtcattacca agatcgtaat
     4501 gttccttgcc gacaatccag gcgcgttttt tactttgtag attaatcaga cgcgcgccga
     4561 ggatacggag cgtatctttg acatggtggg ggagttgatt ttcaagaccg gcacgtaaga
     4621 ctttgctgaa gaaaatatcc agacgctcgc attcccacca gccatccatg taactctcac
     4681 ctaaccccaa cgatccttcc tggaggacgc gtttaaaaaa atcgggattc ttaacacgaa
     4741 tgtcagacgg ggcggaacca ttaattgtaa tatccgcacg acttaacaat tcgttggcga
     4801 ttcggtacca gttatcatcc ggtacgctga cttcttctat acacgatgaa ctcatagttt
     4861 ctccatcact ggacggtgat cagaacctta aaacagcgta gacgcttttt tggctttgtg
     4921 agaaatccca cggacaattc cgtgagccag ttatccgacg tagaacagag gaagggagga
     4981 gcccttgccg aaaaggccat ccatggtgaa tcgggaacac tccggttccc gttaatgcct
     5041 aataattatc gtaatataac aaccgggaat cagtataggc cgcaattttt gatgattcaa
     5101 ccgaaaattg ttagcgtgct aattaccagc ggttaacaag tctttagtga gacttgtcgt
     5161 gggcgacatt ggcatgggga aatccagtct cagcgcaatc tgcatgagac tgcattttgt
     5221 aacctaacgc cgccagaaca acggtagaga gcattacgct ggtggtggtc agcagcggcg
     5281 tgctgatgag ccatgaaacc accaggcttg ccaggaaaca taaccccagt tgcagcgtat
     5341 tttgtagcgc cgcagcgcgc cccgtggctt gagggaaagg gcgtaacgct tgcgcgacga
     5401 cgatagggta gattgcgcca ttagcaatcg ccattacgca gaaaggaatc aggatctcca
     5461 ccagtgaggc attattcaga aggcccgctc cccaggtggc gataacgctc agcgcataca
     5521 gccctaacag ccacggaagc aattggtagc cctgccattt ttgtagcgcc gcgcggcaac
     5581 catatccgcc aatcagaaaa gcgatggttt gaggaacata gctcaggcca atcactgccg
     5641 ggctgtaacc catcgcgctg agaataaacg gggaccctgt tagccacgca aaaaagctgg
     5701 cggaacaggc ggcataaatc agcacattac cgcgataggt tttagagcgt aacaacgtcg
     5761 cgaaagtgag tttatcctgt ccttcggtac gcgcttttac cgatggtttt aagcgcagcg
     5821 ccggcaacat cagcaacaac gtaatcacga acagggtggc gaaaatcacc tgccatgaga
     5881 aatgcgtcag tatccagctt cccagtaagg gcgcaagcgc cggggataat cccaccagtg
     5941 gcatgatcgt ggcgaagata cggttaattt tttgcgaagg ataataatcg gtcaccagcg
     6001 cttgccagat taccgttgcc gcacaaacgc cgacggcctg cacaaagcgc agcgtcagca
     6061 gtgctgccgc gctttctacc cacagcatcc ccagacttcc gagtgcaaag atagataacc
     6121 ccagcagtaa aatcggttta cggccataac gatccgatag cggtccccaa agtagttgcg
     6181 cgacggcaaa gccagctaaa aacaggctta ggctggcgct gacagcggcg gcaggcgttt
     6241 gtaaatccgc ctgtatggcg gcaaacgcgg gcaggtacat gtccgtagcc agaaatccca
     6301 gcacgctaag gccggctaac cagactaaaa aaccttttcc aggttgcata tttgtttctc
     6361 tttcttatca gacagacatt gtcgcagagt gtagggagtg aaattacggt tgtgaaacgt
     6421 taatatttgt ccagtgaatt caaaattttt gtaggcaaat tatgtggtcg gaatactcgc
     6481 ttgaagtggt tgacgccgtg gcgcgcaatg gcagttttag cgcggcggcg caagaactgc
     6541 accgtgtgcc ttcagcagtc agttacaccg ttcgtcagtt agaggagtgg ctggccgtac
     6601 cgctttttgt acgacgtcac cgtgatgttg aactaacgcc tgctggcgtc tggtttttaa
     6661 aagaagggcg ttctgttatc aaaaaaatgc agatcactcg ccaacagtgt cagcaaattg
     6721 ctaatggctg gcgcgggcag ttagctattg cggtggacaa tatcgtcaga ccagaacgta
     6781 cccggcagat gatcgtcgat ttttatcgtc attttgacga tgtggaactg ctggtttttc
     6841 aggaggtgtt taacggcgtc tgggacgcgc tctccgacgg gcgtgtcgaa ctggcgattg
     6901 gggcgacgca ggcgattccg gtaggggggc gttacgcttt tcgggatatg gggaccctga
     6961 gctggagctg cgtagtggca agcgatcacc cgctggcgtc gatgcctggg ccgttaagcg
     7021 atgataccct gcgcaactgg ccgtcgctgg tcagggaaga cacttcgcga accttaccga
     7081 aacggattac ctggttgctg gataaccaaa aaagggtcgt cgtaccggac tgggagtcat
     7141 cggcaacctg cctgtcggca ggactatgcg tgggaatggt gccgacgcat tttgcccgac
     7201 agtggataga cagcggaaaa tgggtggcgc tgacgttaga gaatccgttt cccgatgcgg
     7261 cctgttgcgt gacgtggcag caaaacgagg cctcgcccgc gctggcatgg ctgctggact
     7321 atttgggcga tagcgaaacg ttgaatcggg agtggctgcg ggagccagaa gaggctcccg
     7381 acagcgggga ttaacgccga tagtcgcgga acgggccgtc agcgaccgag cgacgctcaa
     7441 ccaggcgtgg atgaacttca atagactgtg actcttcacg cttattgacg atgcgatcca
     7501 atagcatatt aaatgcggtt tcgcctaaag agtctttggg ctggtgaatc gtcgtcagcg
     7561 ccggggtaaa gaaacgggcg ttacgcacat tgtcataacc gatcaccgaa acgtcctgcg
     7621 gtacgcgaag ccccatttcg tcagctgcgc aaagcgcgcc catcgccata atatcgccgc
     7681 cgcagaaaac ggcggtaggg cgatgtgact gcgataagat ttgctgcatc gcgtggtaac
     7741 cggattccgg ctcgaagtcg ccctgaacaa tccagttgtc cggcacgttg atcagcgcct
     7801 cctccatggc tttcataaag cctgccagcc gccccgcgcc tgtgttgcgc tccagcgggc
     7861 cgggaataac gccgatatcc cggtggccgc gctcaaccag ataacgaccc gccatatagc
     7921 cgcctgcaaa ggcgttatca atcaccgtgt cggtaaaatc ggccttcgcc tcaccccagt
     7981 ccatcaccac catcggaata tggcgatact cttccagcat ggaaagcaga ggttctggat
     8041 actcagaaca catcaccagc aggccatcca cgcgcttttg cgccatcatg gacaggtagg
     8101 cgcgctgttt ttccaggtta ttccaggcgt tgcctaaaat cagcgtatag cctttctgga
     8161 aacagttttt ttcaactgcc tcgataattt cggcaaaata ggccgcttcg ctgctggtcg
     8221 ccagtaagcc tatcgacttg gtatggttaa ccttcaggct acgcgcgacg gcgctgggag
     8281 agtagtgcag ctctttaatt gccgcccaga ccgcgttacg cgtttcttca gcgacaaaac
     8341 gcgttttgtt gattacgtgt gatacagttg tagtggaaac gtttgcccgt ttcgctacat
     8401 ctttaattgt tgccattaca tttcactcca gaccctcgct aagctcctga gaaacgccag
     8461 gtaaacgttt gcctacacac accctaatcg caacatcagg gttgcggcac gccggaaaaa
     8521 cgacacggaa cgtcaggaag gggtcaatgg ccgttacgct aattcagtaa gcctggaatt
     8581 ttgtctgatc ttgaggaaaa ggggaagcgt taaaaacagt tatcaatata aaacatgaga
     8641 gatttttgtg cgggaatgtg caaaaatgcg ctatatcact ttttgtgtgg gaataaaaag
     8701 gagaaaactt gatgagtacc gacctgaaat tttcgttgat tactacgctg attgttctgg
     8761 gcgtgattgt cgcaggtgga ttaacggccg ctctgcactg atttcctctc ttctgagagt
     8821 gggcgtctcc tctattctat ccctctctaa aacgcagaag gcgtaccttc tgcgtactca
     8881 gacttatgcg gcgagatttt tcgcaacaaa ttcccagtta accagcgccc agaaatgctc
     8941 cagatagttt ggacgggcgt tgcggtagtc gatgtaatac gcgtgttccc acacatcaac
     9001 cgtcagcaac ggcgttgcat ccgtagtcag cggcgtaccg gcatttgagg tagaaacgat
     9061 agccagtttg ccatcagcgc tttttaccag ccatgtccat ccggaaccaa agtttttgat
     9121 agcggcatcg gtgaactgcg ctttaaattc cgcgaagctg ccaaaagatg ccgcgatagc
     9181 atcagccagt ttcccggtcg gttcgccgcc agcgtttggc gccaggcagt tccagtagaa
     9241 ggtgtggttc cacacctgag cggcgttatt aaagatgccg ccttcggaag tgcgcacgat
     9301 ctcttccagc gatttgcctt caaacgccgt gcctttgatc aaattgttaa gattggtcac
     9361 gtaagtctga tgatgtttgc catagtgata ttccagcgtc tcagcagaaa tatgcggcgc
     9421 cagagcatct ttggcatacg gtaatgcagg taattcgaac gacattgctt ctctccttat
     9481 tattaatatt gcgcacgcac aataaccctg gtgcgcgtaa ggatagggta gcaaattgag
     9541 aggtggcgca aaagaagaag ttatcctgtc gttaaacgac aggataaaat attagcgaat
     9601 tgttttaggc gtcatcaccc ggcgggcgcc gacataatga cgctgccagt actcttcgtt
     9661 cagtgaggtg atcttaattt cctgaccgct gcgcggagac tggataaact taccgttgcc
     9721 gacatagacg ccaacgtgat cagcggtgcc gcgcccctgt gtacggaaga acaccagatc
     9781 gccgtttttc aactcgctac gctcaatggg ggccgcgtca cgcaggtgat acatctcatt
     9841 cgccgttcgg gggatacgga tcttcactaa atctttatag gcataataaa ccagaccgct
     9901 gcaatcaaaa ccggtgcgcg gcgatgcgcc tccccagtga tacggtttac caatctgatt
     9961 catgagcttg gacatcgcgg ttttcgtcgc cttttgtact tttgcacgat gcgcatcggc
    10021 aatagagacc ggcaatgttc ctttcccctt cacgcagtgc ggcttacggc ctttacgcgt
    10081 cgtgcatttt tccgttacgt cgagggcggc gattgacgtg ggcgcggttc tgttacgacg
    10141 atgcgtcgta tgacgagatt ttgtggcggc ggtggtacgt tttggcgtag aagcggaaga
    10201 agaacggctg gtttttgagg ttttttttac gttttttttg ctggttttac tgatcttttt
    10261 agttgtgctt ttctttttat ctgccgtttt cgtgacatga gaaacagcag gcgtcgcttt
    10321 ggcttgcctg gaagcatggg ccattggcgt aaaggggaga gtagtaaaaa gtaaagcaca
    10381 gagcgtgatc gagattttgt ttatccgcgc cactgagcaa tcctctgtta aaggcaggcg
    10441 attcatgcct gcgtatgatt tacaaaacct gataattcta atctacaaaa gcacagattg
    10501 gtaattgctt ttggtttctg aagctatgtt tcgttaacag atgtaaaaaa atagcaatta
    10561 atgctaaaca cgaacgcgtt atctacaaat cactgcgcgg caacccgctt aaaagatatt
    10621 ttgtatacaa cttattcccg cagacggtaa aataataagg catgatgaaa atgttatttt
    10681 ccgttgccag cctgacccgt tacaatgaca ggcttcggtc gtaaaagtag tttaaggaag
    10741 cgagacaatg agcaccacta tcgaaaaaat tcagcgccag atcgctgaaa acccgattct
    10801 cctgtatatg aaaggttcac cgaaactgcc aagctgtggt ttctctgcgc aggccgttca
    10861 ggcgctttca gcctgcgggg aacgttttgc ctatgttgat atcctgcaaa acccggatat
    10921 tcgcgctgaa ttaccgaaat acgccaactg gccgacattc ccacaactgt gggtggacgg
    10981 cgagctggtc ggcgggtgtg atattgtgat tgaaatgtat cagcgtggcg agctgcagca
    11041 gcttattaaa gaaactgcgg caaaatataa aactcaggag ccggacgcag agtaatctgt
    11101 gaaaggggaa agcgacctgt aaaggtcgct tttttaccgc catcgtgagc aagagcggcg
    11161 ttgttagcct cgttatttgt ccgtcggcaa aggtaacggc cagccgccca ggcgcttcca
    11221 gcgattgacg atttcacaaa acagcaccgc tgtccgctcg gtatcataca aagcggaatg
    11281 ggctttttca ccgtcaaact ccatacctgc cgccaggcac gcttttgata acaccgtttg
    11341 tcccagcgcc agtccgctca atgccgcagt atcaaaggtg acgaacggat gaaacgggtt
    11401 acgtttcagc gaggcgcgct ctgcggcggc catcataaaa ctgtgatcaa aagtggcgtt
    11461 atgcgcgacc ataatggcgc ggctacaacc gctgtctttg atacctttac gtaccatttt
    11521 gaaaatagcg tgtagcgcct catattcact caccgcgccg cgtagcgggt tagagggatc
    11581 gataccgtta aacgcaagcg cttccggctg taagttggct ccagcgaacg gctctacatg
    11641 gaaatgcagc gtcatgtccg gcatcaacca gccttgttca tccattttca gcgtgatggc
    11701 ggcgatttcg agcagcgcat cggttttagc gttaaatcct gcagtttcaa cgtcgatgac
    11761 gacaggataa aaaccacgaa aacggtcgca cagaccggaa agttgagcgt tatcggacat
    11821 ctgagtctct taatacgaaa aaatgcagcg cgtattatgg caaattttac gccgggatgc
    11881 agtaaaacaa cgggcgcagt gacctgcgcc cggcggggga tcagttaccc agaccgcggc
    11941 ctgcgtcttt agcttcaatc aattcgattt tatagccatc cggatcttca acgaaggcga
    12001 tgatggtcga accgcctttt accggccccg cttcacgggt cacgttgccg ccgttctgac
    12061 gaatgcgttc acaggcttca gcagcattgt caacgctcag cgcgatgtgc ccatacgcat
    12121 tgcccatgtc gtagctctca acgccccagt tataggttag ttcgatgacc gcttcttccg
    12181 tttccggacc atatcccaca aaggccagcg agtatttgta ttccggattc tcactggtac
    12241 gcagcaattt catgcccaga acgttagtgt aaaaagcgat ggaacgctgc aaatcgccga
    12301 cgcgcagcat agtatgcaat aaacgcattt tcgttgtcct taaaatagtc aagatattca
    12361 aagtatagcg gcgatgtgag gccgctatca atgaaattac agagtagggt agtcagtgta
    12421 gccttccgcg ccgccgccat aaaaactttc gggacgctgt ggattaagtt ccgctttacg
    12481 ttgcagacgc gccaccagat ccgggttagc gatgtaatcg cgaccaaacg ccacggcgtc
    12541 aatcagccct ttttcgatca gatcttccgc tttttctggc gtataggcgc cagcgccgat
    12601 gatgggaccg tggaaacgcg cgcgcacttt ttcacggaac gcgtcgctgt acggttcgcc
    12661 gcccgcccag tctggttcag acatatgcag ataagcgatg ccgcgtttgc ctaacgcttc
    12721 aatcagataa agggcgtcag cttcttcatt cgggccgtta tcgacattct ggaaagtgcc
    12781 gacaggagaa aggcggatgc cgatacggtc cgcgccccat tccttaatgc cggcatcaac
    12841 cacctccagc accagacggg cgcgattctc tacgctgccg ccgtaccgat cggtacggtg
    12901 attagaagac ggtgagagga actggtgcag cagataaccg tgcgcggagt gcagctccac
    12961 cagatcgaag cctgcctctc gggcattggc gatagcctgg cggaaatcgt tgacgatccc
    13021 ggggatctca tgagtatcca gcgcgcgcgg cgtggaagtt tctacgcgga tggcctggcc
    13081 gttttcgtca cgcaaagagg tgcgggttcc cgcattgata gcggatggcg cgacgggcgc
    13141 ttgtccgcct ggttgcaggc tggcgtgtga aatacggccc gtatgccaca gttgcaccgc
    13201 catatggccg ccctgggcat ggactccctg agtgattttt ttccaggcgg cgatctgctc
    13261 atcgctgtgt aatcccggtg cgccggcata gcctttcgcc tgcgcggaga tttgtgtggc
    13321 ttcgctgatg atcaatccgg cgctggcgcg ttgacggtaa tattccgcca ttaacggcgt
    13381 aggaatgtcg cccggttcaa tactccgcaa acgcgtcaaa ggcgccataa atacgcgatt
    13441 tgtcgccgtg atggcaccca ccttgagggg ggtaaacagt tttgctgatg acatagtggc
    13501 tcctgatata agtagaccgg tcgtcttgta ataaaggaaa taaaaacgcc cgttactgct
    13561 caggcgttgc aatgatggtc ttaacatgcg ccaacgcatt ttccagcggc gcggcgctac
    13621 gggatatttt ggcctgcaaa ttggcgccca gccacagggc ataaagtacc tgcgcctgtg
    13681 gcaacggctg gccggtgaaa tgtaaacagt ggctattacg gccatcttcc agcgcgcgtg
    13741 caagcagtgc catgatctcc tgcgcccctt tatccatcgt agagcgcata tcctccgaca
    13801 gatcgcagac ttccgctgac agtttcaccg tcaggcaacc gctgatggcg ccttgctggc
    13861 aaaactgctt taacgtttcc tgataccagg cgagaagacg atcgcgatga ttaccgggac
    13921 cggaggtgaa gtgcgccgta agacgctgat gatagcaggc gtaatgtcgc tcaagcatgg
    13981 cgacgccgaa ggcttctttc gagcgaaagt agtgataaaa cgacccttta ggtacctggg
    14041 cggttttgag caactcgcta agccccatgc cggtaaaacc ccgttgcata caaagctgct
    14101 cgccggtggc cagcagatgt tcgcgggtat catgttcggt ttgcttattc atgacaggca
    14161 gtatagtaga ccagtcggtc tactgcaagc agagttgcca taatgtcagt tagcgtcttc
    14221 aatagtcata agcgccaaac gttgaggagg ggatgtggcc gagcagttgg agttttttcc
    14281 tgtagcaagc ccatgtcgcg gtatctgcca gtctgatgag cgtggctttt gtcggggatg
    14341 tatgcgcagc cgcgacgaac ggtttaactg gcaaaaaatg agcgatgccg agaaacaaaa
    14401 tgtactgcgg ctttgtcgcc agcgtttctt gcgtaaaata cgcgcaaata agcctctccc
    14461 atcggaagat cctcaacaac cttcactctt ttaaacgcgg aattgcgtat actcaacctc
    14521 attattctct atgaggaatc tgttatggtt cagcgtgtca ccatcgctcc acaaggcccg
    14581 gaattttcgc gttttgtcat gggttactgg cgtttgatgg actggaatat gtccgcgcgt
    14641 cagttagtga gttttatcga agaacatctg gatttgggcg tcactaccgt tgaccatgcg
    14701 gacatttatg gcggttatca gtgcgaagcg gcgtttggcg aggcgctaac gctggcgccg
    14761 catttgcggg aaaaactgca aatcgttacc aaatgtggta ttgcgaccac cgccagagcg
    14821 gaaaataggc tcggtcatta tattaccgat cgccgccata ttattctgag cgccgaacag
    14881 tcattaaaag atctggcgac agattatctg gatatgttgt taattcaccg tcccgatccg
    14941 ttaatggatg cggatgacgt cgccgaggcg tttcaacatc tacatcaaag cggcaaagtg
    15001 cgccattttg gcgtttctaa ttttacgcca gcgcaattta cgttgctgca atcgcgcctg
    15061 ccgttcaccc tggcgaccaa ccaggtggag atctcgccgg ttcaccagcc tttgttgctg
    15121 gacggcacat tagatcaatt acagcaactg cgtattcgtc cgatggcctg gtcatgtctt
    15181 ggcggcggtc gtctgtttaa tgatgaggct tatcagccgt tgcgccagga actttccgtt
    15241 atcgcgcaag aactcaacgc tagttctatt gaacaggtgg tctatgcctg gattttacgt
    15301 ttgccgtcgc agccgctgcc gattattggc tcgggtaaaa tcgaacgcgt acgcgccgca
    15361 ctagaagcgg aaacgctgtc attgtcgcgt caacagtggt tccgaatccg caaggcggca
    15421 ctgggttatg acgtgccgta atcgccaact cgttgacttt ccgttcatgt tttcgccagt
    15481 ggtttacact taacaggcga ccacatgtaa cggaggtttt atgaagcgat taagtttagc
    15541 gatggtgacg ctgctggcct gtgcgggtgc gcaggctgcc agcgagaaag tagagatgaa
    15601 tctggtgacg gcgcaaggcg taggacagtc tatcggcacc gtcgtcatcg atgaaaccga
    15661 aggcggctta aaatttaccc cacaccttaa agcgttgccg ccgggcgagc atggttttca
    15721 cattcatgcc aaaggtagct gccagcccgc gattaaagac ggcaaagcgg ttgccgcaga
    15781 agccgctggt ggtcatctgg acccacaaaa taccggtaag catgaaggac cggaaggtca
    15841 ggggcatctg ggcgacctcc cggtgttagt cgttaataat gatggtatcg ccaccgaacc
    15901 ggttactgcg ccgcgtctga agtctcttga tgaagtgaaa gataaagcgc tcatgatcca
    15961 tgtgggcggc gataacatgt ccgatcagcc gaaaccgctc ggcggcggcg gaacgcgtta
    16021 cgcctgcggc gtcattaaat aacccggaga cagtgttccc tgcgctggag cctgttccag
    16081 ctgcgacagc gaacagtgta aacgccagat aatcgccgcc agctcatgcg cggcgggttg
    16141 atgatgatgt gcgagcgtgt cgcagatacg ctgtagttcc tgtagcgtga cggcaagcgg
    16201 gcgttgctgc acgtcgcgct cgctcatcac atcgcgcagc agggatatac aaatatcccg
    16261 cacccgggaa agcggatcgg aacgcgactc ccaggcgcgc agctgccaca ccacatgcga
    16321 gcagttcagc agcaccactc cccaacgtaa taaccaccgg cgcgccagcg catcctgact
    16381 attgctgagc tgactgacgt gatgataggt cagcgattca aactcgcttt cgctatggga
    16441 agggtgacgg ctaagctgat cgacgaaatc ccggcgtagc gcgcggatat ggcggcggct
    16501 ttttacggca tcggaaccgg ggcgcaaaat cgcaaacgcc agccaggaaa tcgcgacgcc
    16561 gacgatcttg gcggtattat cgttaaggaa gtcggcgaag tcgtacaccg gtggattggt
    16621 cacggcgatg aatgagccca taaaaacgat aagctgcccc cacagtcccg ccagcttagg
    16681 catctgcagt ttaagcagtt gcatcgtgac gaacagcgga aaaaggaaaa gcaagaattg
    16741 ccacagatcg gtgatttgca ccatcaggcc aaatttcacc acgaagctga ataaggacag
    16801 cagcactaaa gtacgcatca ataaggaaag cgacttaaac ggcgtggcga cgatggagta
    16861 gaggacgcaa ctgatcgccg ccagggttaa tgcgccgggc ccggattccc attgcacgcc
    16921 aatactccag gcgccaatca ccgtgagcgt gcaaaaggta cgcacgccgc tccagatggc
    16981 ctctgcgtta tccgtatgcc gcgcaaggcc gggagtgcgg cggatatgga tttgatccac
    17041 cggcgcgccg ctttcgatca gatataattg acggctgctg cgcagatata gctggcaaaa
    17101 atagcgtaat cgctgccaga acgcgaggtg acgataatcc tgttcatcct gcgggcatag
    17161 cggcgcaata atccgcgcca cggtgtagct gtccgcgcgc ggttttgcca actcagctaa
    17221 gagttgttca atgacttcgc ggctgttttc cggcggcgtc ggccagttta aaagcattct
    17281 acgcagactg gagatcacgc tggttagccg taattgctgg tgtaacaatg catttagcaa
    17341 tgcattctga cggcgaaaac ggtagtgact ccagaaggcc tgaatacgca gcaggttcat
    17401 ggtcaggatt tgcccaatga ccccctcatg cgcggagcgg atagcgtcgg tagtctccgg
    17461 ctgccacagt agactggcat gttccagcaa gcgcgcatgc atgtttttca acgcggtgag
    17521 cagggcagtg ccatccgatg tgctgggtag gatcatcatc atcatgccgc cacagaggat
    17581 gccgacgata acttcacata cacgtgcctg ggcgatatcc cacaactgcg tgatttctac
    17641 aatattaacc atcgggaacg cgatgatcgc cgccgtgtag ccggacaact ggaaagcata
    17701 agcggcatta ttggtaaaat gcgcgcaggc ccaggtacaa aaaccgatcc aggcggccat
    17761 gctaaataag aacaaccagg gttcattcag cgtatggccg gcaataatca acgcggcggt
    17821 cgcgccgagt aaactcccgg caatacgccc cagactttta ctgattacgc cgcctacggt
    17881 cggaaagctc accactgcgg ccgaagtcat cgcccagtag ggctcatcca gattgagata
    17941 ataagcgaat gtcagcgcga gacacatggc aatggtattg cgcaacgcgt aacgccactg
    18001 gccggaggtc gctttaaacc agggcgtatt tcgcagggcc ggcagggaga gtttcattac
    18061 cgctgtccaa tggctacgct gcaggtagtg ccggagacga gcgtgatatc ctgcggcaaa
    18121 gcgtcaaatt cgatacgtac cggtacgcgt tgcgccagac gtacccacgg tacgttgggt
    18181 ttgatatcgg gcactaaacc ggagtcactt tccacgcttt ggtcgtaaat agcgcgcccg
    18241 atactgccaa cgtgaccctg taacttaaca ttgccactat acagtgttat taatgcaggc
    18301 tcaccttcgc ggatatggcg tagtttggtt tcttcgaaat atcccattac ataaaatgaa
    18361 tggctatcta ccagggcgaa aagtggctta ccggtgctag cataatcacc ggtacgcgtg
    18421 gaaaggttgg tcacccagcc ggataccggc gcttttactt ccgtctggct aagctgccac
    18481 tgcgcctgtt ttaacgttgc cagtgcgaca tctacgctgg cctgcatcgc tttaacattc
    18541 agattggcgc tatccagatc ttcagcagag atgtagttac gcgataaatg tcgacgtcga
    18601 tcggcttcat tattcgcttt tgccagatcg gactgcgctt tggccaactg tgcctgcgcg
    18661 ttaagttctg caatatggaa gggcgtttta tcaatgacaa agagaacgtc cccagcgttg
    18721 acgaactgat tatctttgat attgagttgg gtaatgctgc cagaaacctg tggcgttacg
    18781 ctgacctgtt ccgcgcggat tttaccatcg cgcgtccacg gtgactgcat atagtaattc
    18841 cataaccacc acgcggccag aacggcgacg acggcgacaa tgagagtaga aaaatatttt
    18901 attgttttta acgacatatt taccacacga tcagtaaaac gaggcccaga catacgcaaa
    18961 gcgtaaagag ggagagatcc attaacaggg gatgccagat ttcatcagag tatatccggt
    19021 cacgcaggag tcggtgaata aacaaccaga taacgaaccc aagcgcaaag gctttgaaga
    19081 atggcggaaa gtaaacagat gctcccaaca tgagatcttg taagggcaat cctgtggcgt
    19141 tgagtataca cttcacaagc aatgttcctt tgcgtcagac atcgatgctt tagttttagc
    19201 caaaaccgaa gctacaggtg ccaggtgcgc actatgtctg aaaaaatgtc tattggtaag
    19261 caaatttagc aatacatttg ttttgagaat acaaatactg cacactattc taaaatcagc
    19321 ataataactt agcaagctaa ttataaggag gtgaaattgg aatcgccact aggttctgat
    19381 ctggcacggt tggtgcgcat ttggcgtgct ctgattgacc atcgcctcaa gcctctggaa
    19441 ttgacgcaga cacattgggt cacgttgcac aatattcatc aattgccgcc tgaccagtcg
    19501 cagattcaat tggctaaagc gataggcatt gagcagccat cgctggtacg cacgttggat
    19561 caacttgaag ataaggggct aatttcgcgg caaacctgcg ccagcgatcg tcgcgctaag
    19621 cggattaaac tgaccgaaaa agcggagccg ctgatcgctg agatggaaga ggtcattcat
    19681 aaaacgcgcg gtgaaatttt ggctgggatt tcttcagagg agattgagct tctgattaaa
    19741 cttgtcgcta aacttgaaca caacattatg gaattgcact ctcacgattg aggtgcaggg
    19801 gcatacgtgt ggccatgtga ccacacgtaa agcctggttt agcgtggaga gacagtaacc
    19861 tggctgccgt tgctggccag cacgacacgc tgacctgccg agaaacgcgt atttccttgt
    19921 ttctgcacaa ccataatggt gttgccatcg tctttacgaa tttccagttc cacaccctgg
    19981 gttttattca ttgcgctctg gacgccctgg cccgctacgc caccagccac cgcgcctgcc
    20041 gcggtcgcca gtgaacgacc cgtaccgccg ccgatagtgt tgccgaggaa tccgcccaac
    20101 accgcgccgc cgatagcgcc aatcacgtta gaatcatcac cgccctgaat ttgaaccgga
    20161 cgaacgttaa cgatagtacc gtacgttaca ttctgaactt gtttagcctc ggatgcggta
    20221 taaacatcac ccgaaaggct atcattgtta acacacccag ctaaggataa ccccatcagt
    20281 gaaacggcca gtacacgttt aatcatttac ccatctcctg ttcttcacga aacgctattt
    20341 cagcatccct atagctaaat tatatggcat ttatgcagtt aaggtcatat cttctgccga
    20401 aagaatgtaa aaatcataat cagaagttaa ttaactaatc ttaaacgaag tgggaagcaa
    20461 gaaaagatag gttattgata tccgtggacg gcacggcaaa aaacgtgacg cgggcatcgc
    20521 attgcaaaat acgttatgcc gagtgttaag gcttaaccca gcttaataag gaagaggtat
    20581 gaaatcgggc cgttttattg gcgttatgtc cgggaccagc cttgatggtg tggatgttgt
    20641 actggcggca attgatgaaa ccatggttgc gcaacaggca agtctcacct ggcccattcc
    20701 cgttcatctg aaaaaaggca ttctcgatat ttgccaggga caaccgctta cgctctcgca
    20761 actcggccag ctggataccc agttaggccg gctttttgca caggcggtta atgcgctgtt
    20821 agcgcaacaa cgtttgcagc cgcgggatat cgtcgccatt ggttgtcatg ggcaaacggt
    20881 ctggcatgag ccgaccggcg aggccccgca tacgctgcaa attggcgata ataatcacat
    20941 cgtcgcccat acggggatta cagtggtcgg cgattttcgg cggcgggata ttgcgctggg
    21001 cggacaaggc gcgccgctgg tgcccgcttt ccatcacgcg ctgttgggac atccgacgga
    21061 aaaacgtatg gtcctgaata tcggcggcat cgccaattta tctctgcttt tccccggaca
    21121 ggcggtgcgc gggtacgaca cggggccggg taatatgttg atggatgcgt ggatttggcg
    21181 acaatgcgcg cagccctacg acaaagacgc ggcatgggcg aaagaaggtc aggttattct
    21241 tccattgctg caaaagatgt tgcgcgatcc gtactttgct gcgtcggcgc ccaaaagtac
    21301 aggacgcgaa tatttcaact atggctggtt agagcgtcat cttacggctt tccctggcgc
    21361 agacgcgcgc gatgtacagg ccacgctggc ggagctgacg gcggtctcca tcgcccaaca
    21421 ggtgctgctc aatggcggct gcgagcggct gatggtctgt ggcggcggaa gccggaatcc
    21481 gttagtgatg gcccgtctgg cggcgctgtt gcccggtatc gaggtttcga ccaccgataa
    21541 ggcggggatc agcggcgatg atatggaagc gctggccttt gcatggcttg cctggcgaac
    21601 gctcgcgggc ctgccgggaa atttaccttc cgtgacgggg gctacagaag ccagtgtttt
    21661 aggcgctatt tacccggcta acccaataac tcagagttaa ctgaattttt cccggaccct
    21721 atatcggtaa actagcaagg tcaggaaggg gcgtttgccc ttccagaagc aggagagctt
    21781 tcgggatatg cctatgaaaa agatcgcaat aatgttttta cctgtgctgc tgaccggctg
    21841 tagcgtttat caacaatttg ttgaacgtat gcaaacggat acgctggaat atcagtgtga
    21901 tgagaagccg cttaccgtta aagccaataa cccgcgtgaa gaggtcagtt ttgtttatga
    21961 caataagctg ctgaccctga agcaaggaat ctcggcctcg ggcgcgcgtt ataccgacgg
    22021 gatttatgtt ttctggtcgt aaggcgagag cgccacggtc tataaacgag acagaattgt
    22081 gcttaataac tgtcagttac aaaatccgaa gcgttgagat tttcagtatg ggggcgcaca
    22141 atagcgccac ccactgatta tttctgatca acgccatgtc tgataacaac caattgcagc
    22201 agatcgcgca tctgcgccgt gaatacacga aaggcggctt gcgtcgccgc gatttacccg
    22261 ctgaaccgtt aaccttattt gagcgctggc ttgggcaagc gtgtgacgcc agactggccg
    22321 atccaacggc aatggtcgtg gcgaccgtag atgacaaggg gcaaccgtac cagcgtatcg
    22381 tattgctcaa acattatgat gaaaaaggcc tggtctttta tactaacctg ggaagccgca
    22441 aggcgcatca aattgagcac aatccgcgta tcagtctgtt atttccctgg catatgcttg
    22501 aacgccaggt gatggtgaca ggcaaagccg agcgtctctc cacacttgag gtggtgaggt
    22561 atttccacag ccgtccgcgc gacagccaga tcggcgcatg ggtctctaaa caatccagcc
    22621 gcatttccgc gcgcggtatc ctcgaaagca aattcctgga gctcaagcag aagtttcaac
    22681 agggcgaagt gccgttaccc agcttctggg gtggttttcg cgtgagtatc gaacagatgg
    22741 agttctggca gggcggcgaa catcgtctgc acgatcgctt tttataccaa cgcgacgacg
    22801 gcgcatggaa aatcgaccgt cttgcgccct aaagatgcaa aaatcttgtt ttaagcactg
    22861 gtgcggatga atccgccgtt ttatgctatg tctctttcgc gtctggcgaa aagtcgtgta
    22921 ccggcaaagg tgcagtcgtt ttatacatgg agattttgat ggcaagcagt aacttgatta
    22981 aacaattgca agagcggggg ctggtagccc aggtgacgga cgaagacgcg ttggcagagc
    23041 gactggcgca aggcccgatc gcgctctatt gcggcttcga tcctaccgct gacagcttgc
    23101 atttggggca tctggttcca ttgttatgcc tgaaacgctt ccagcaggca gggcacaaac
    23161 ctgttgcgct ggtaggcggc gcgaccggtc tgattggcga cccgagcttt aaagccgccg
    23221 agcgtaaact gaacactgaa gagaccgttc aggagtgggt ggcgaaaatt cgtaaacagg
    23281 ttgccccatt cctggacttt gattgcggcg aaaactccgc catcgcggcc aataactatg
    23341 actggttcgg cagcatgaat gtgctgactt tcctgcgcga tatcggtaaa catttttccg
    23401 ttaatcagat gatcaacaaa gaagcggtga agcagcgtct gaaccgtgac gatcagggta
    23461 tctctttcac ggagttctct tataacctgc tacaggggta cgacttcgct tgtctgaata
    23521 aactgcacgg cgttgcctta cagattggcg gttctgacca gtgggggaac atcacttccg
    23581 gtatcgacct gacccgtcgc ctgcaccaga atcaggtatt tggtttgacc gttccgctga
    23641 ttaccaaagc tgacggcacg aaattcggta aaaccgaagg cggcgctgtc tggctggatc
    23701 cgaagaaaac cagtccgtac aaattctacc agttctggat taacaccgca gatgccgatg
    23761 tttatcgctt cctgaaattc ttcactttta tggacattga ggagatcaat gccctggaag
    23821 aagaagataa aaacagcggt aaagcgccgc gcgcgcagta tgtactggcc gagcaggtga
    23881 cgcgcctggt tcatggtgaa gaggggctgg tcgcggcgaa acggatcact gaatgcctgt
    23941 tcagcggttc actgagcgcg ctgagcgaag ctgactttga gcagttggcc caggacggcg
    24001 taccgatggt tgaaatggaa aaaggcgccg acctgatgca ggcgctggta gacgccgaac
    24061 tccagccgtc acgtggtcag gcgcgtaaga ctatcgcctc caacgctgtc actatcaatg
    24121 gtgaaaaaca atccgatcct gaatacatct ttaacgatga ggaccgtctg tttggccgct
    24181 ataccttatt acgtcgcggc aaaaagaact attgtctgat ttgctggaaa taaggcatta
    24241 agtaacaggg agtgagaaat cactccctta tttttgatgt tcaggtaaaa aaatgaagaa
    24301 tatcctcgct atccagtccc atgttgtttt cggacatgcg ggcaacagcg ccgccgaatt
    24361 tcccatgcgc cgtcttggcg cgaatgtttg gccgctgaat accgttcagt tttctaacca
    24421 cacgcaatat ggtaaatgga ccggctgtgt catgccgccc agccatctga ctgagattgt
    24481 ccaggggatt gcggacattg gccagttagc gcactgcgac gccgtactta gcggttacct
    24541 gggatctgcc gagcagggag aacacattct cggtattgtg cgccaggtta aagcagcaaa
    24601 tccgcaggca aaatatttct gcgatcccgt gatggggcat ccggaaaagg gttgtatcgt
    24661 ggcgcctggc gtcgcagagt tccatgtgcg ttatgcgcta cccgccagcg atattatcgc
    24721 gcctaacctg attgaactgg aaattctcag caaacatagc gtgaataatg tgaatgacgc
    24781 cgtgcaggtg gcgcgagaac tgattgctca ggggccagaa attgtactgg taaaacatct
    24841 cgcccgcgcc ggttacagtt cagaacgctt tgaaatgctg ctggtgacag cgcaggaagc
    24901 ctggcatatt agccgtccgc tggtggattt cggctcacgt cagccggttg gcgctacagc
    24961 gagctatccg gcaacatgac attaattcag tccttccgct ttaagcgctg ccgcaacggt
    25021 cggtcttttt gcgacacgct gcatataact ttcaatatgc gttgacccgt ccatattcag
    25081 ttttacgcca taggcccaac gcaatacggt aaacagataa gcgtctgcaa tggtaaaacg
    25141 ctggccgcaa atccactggt cgtctgaaag cgactcatcc acatactgaa atttcttttc
    25201 cagaccggcg cgaacggcgg gtttaagtgt ttccggcgtg tcagggcgga acagcggggt
    25261 aaagccttta tgcagttccg ttgcaatata gttgagccat tccagcgtat gatagcgagc
    25321 aagactactt accggcgcca gaagctggcg gtcgggaacg ctgtcggcga ggtactgcat
    25381 aatggcgacg ccttcagtca acagtgtgcc gtcatccagc agcagagccg gaacctgtcc
    25441 tttagggttg actgccaggt aatcatcacc gttttccagg cgttttttcg cgagatcgac
    25501 gccatcaagc gtaaagtctt tgccaatttc gcgcaggata atatgggaag caagagagca
    25561 ggcacccggt ttgtagaaca gtttcatcgg taactccttt ttgctgaggt ttaaagtatg
    25621 gtagtgcggg gacgagcaaa aaaaaagccg ctaacgcaca gttagcggcc tgaatgttgt
    25681 ttcccggaaa attaaactgt agcggcttta gagccttttt cagcggtatc atcgtcctgg
    25741 gtcatacggt tcagcttagg cgctgtcagc agcatcagga cggcgataac ggcggttgct
    25801 atgccaatct gcataaatac gcgaccatag acttctaggg acatcagtgg gtcagtcacg
    25861 tcgctcggca cagccatcag gttggcgaca taaccgccga tgatgttagc gcctgccgtt
    25921 gtcaggaacc agctacccat gatgaagccc atcagacgct gcggaaccaa ctgtgcgacc
    25981 attgccaggc ccagaccgga gatcatcagc tcaccgatac tttgcaggcc gtagcttgcg
    26041 atcagccagt ttacggatac gatgccggca tcgttcgcaa atttggcgcc cagcggcaga
    26101 atcaggaacg cgccggaaca cagcaccata ccaatggcga atttcatcgg catcggcagc
    26161 gtatcgccca tcctgttata aatagcggcc agaatcgggc tgccggtaat gatccagaat
    26221 gggttcagcg cctgatactg ttccggttcg aacgcgatac cgagaataga gtgctcgacg
    26281 ttacgaatgg caaagaagtt cagcgacgtc ggcatctggc tgtacagtac gaagaagata
    26341 atcgcctgca gcatcaaaat aaaggcgacg atcattttac ggcgagccgc gccgtgcatg
    26401 gaaaacgctt ctttaccgaa aataatgacg atgccaagag cgattacgcc cagcaccata
    26461 cgcgcgatat cctggttgtg cagcagccag gtggcgaccg caatcagaac gacaataccc
    26521 acgattgtca gcagcagatt acggaagttg atcggttcaa agtcgggttt ggaaccgtag
    26581 cttttcaccc agcgctggca gaaagcaaag ttaacgacgg ttatcagcat accgacgacg
    26641 ctaagcgcaa acgcggtgct ccagccataa cgcgccgcca gccacggcgt cgccagcata
    26701 gagaagaagg agccgatgtt gacggacata taatacatcg taaatgcgcc gtcgagacgc
    26761 ggatcgtcct tcgcgtaaca ggtagacagc agggaagacg ggttagcttt aaacagacca
    26821 ttacccacag cgatagccgc catgcccata tagacgatgc cagcgtcatg accagaccat
    26881 gcgaccagcg cataaccgat agccagcacc acggcaccca gcataataac gcgtttggtg
    26941 cccagaattt tatcacctaa ccaaccgcca atggcgacca ggccgtacac cagcgcactg
    27001 aaggaagaga aaagggtgat ggaatccgct tctgacatac ccagttgttt taccaggtag
    27061 acggccataa tgccttgcag gccgtaataa ccaaaacgct cccataactc tatcgagaag
    27121 attagataga acgccttcgg ttgtttgaaa gcgttcaaac tgacgctttc agttggtttt
    27181 ttgtttgcag tagacacttt tacctctttt ttacgccccg tattaacagg gattgtctgg
    27241 cgcgtgatga gtcagactca tccgtccgat tgttatattg gaggggaaac ggcaggtaat
    27301 gttcactatc tttcctctcc agacaagagc tttgtaataa tctgttacat ataactcttc
    27361 tggttgaatc gtccgatgtc agaaatgtta tccagcgtta aatttcttca tttgaagaat
    27421 ggcagatttt tacactgcaa aaaggccatt agtttggata aaaggcgata tcttctgcta
    27481 tttaaggtga aaagcagtga tataggccat tatctgaaaa aatggcagag taatgttttg
    27541 tagtgaaaac ggggcgtcag tctatccggt tgtaaatgta accttaggtg tcattaaatt
    27601 tcacatgaag ttatcaaagt gatcctgatc acggatagat agaaattttt gcgattaaaa
    27661 aatgattaac ctgacgtgga gggaaaacga aagcacatta catcagaaaa aggacagaga
    27721 ctggaatgat tgatggctaa aatagatcca ggccgaaggt gggagcgcgc tggtatgacg
    27781 ggcgcactcc gaccatatca aatatcgact ttttctttgt attcgcaaag gtcttcaatg
    27841 aggcaggagc cgcagcgggg ttttcgggcg atacaggtat agcggccatg caaaattaac
    27901 cagtgatggc agtccacttt gaactcattc ggcaccactt tcagtaactt ctcttctacc
    27961 tgctcgacat ttttacccgg cgcgaactgt gttcggttgc atacacgaaa tatatgcgta
    28021 tcaacggcga tggtcggcca gccgaaggcg gtatttagca ccacgttagc ggttttacgc
    28081 cccacgccgg gaagcgcttc cagcgccgcc cgatcctccg gcacttcgcc attatgcttg
    28141 tccattaaaa tacggcaggt cttaatcacg ttttccgctt tactgttaaa taagccgatg
    28201 gttttgatat aggatttcac gccttctacg cccagttcca gcatcgcggc tggcgtattg
    28261 gcggccgggt aaagtttggc ggtcgccttg ttcacgctga cgtcggttgc ctgcgcggaa
    28321 agcaacacgg caatcagcaa ctcaaacggc gacgtgaaat tgagttccgt tgtggggtgc
    28381 ggattgctgt cgcgcaggcg cgtcagaatt tccagccttt ttgctttgtt catcagactt
    28441 tccctgtttc accggccgga acagcggaag gcgcggtttc ggcgcggcgt ttcttcattt
    28501 tttcatcaat aagatatttt accgccagca tgagtcccag accgataaac gcgcctggcg
    28561 gcagcatcgc cagcaggaaa ggcgagtcgg tgtgaaatat ctcgacccgt aatacttttg
    28621 cccagcctcc cagcaggcta tccgcgccat cgaaaagcgt accattcccg aggatctcgc
    28681 gcagtgagcc cagcacgaac atcgcgcctg tcgcgcccat gccgatggaa aaaccgtcca
    28741 acgcggaaag ccacggtcct tttttcgcgg caaacgcttc ggcgcgacca acaactatgc
    28801 agttcgttac aatcagcgga ataaaaatcc ctaaagactg atacagaccg aacgcatacg
    28861 cattgatcag catctgtact gcgctgacca ccgaagcaat gatcataacg taaatcggga
    28921 tacggatttc tgccggcgtc cagcgacgta gtgcggacac cgtaaggttg gtcagcgtta
    28981 ataccagcgt tgtggcgaga cccagcccca gagcgttggt tgccgtagac gtcactgcca
    29041 gtaaagggca caggccaagt agctgcacca gagcagagtt atttttccat aacccctgaa
    29101 caacaatgtc ttttatttcg ctcatggcta ttctccacag gcggttaaat gggggagctg
    29161 agcgggcagt gattcggcgt acagcccggc gcgtttaacc gcattcacta cggcgcgcgg
    29221 cgttattgtc gccccggtaa attgatcaaa atcaccgcca tcttttttca ccgcccagtg
    29281 cgtatcattt tcaccgctga tggttttacc gctaaagtgg gtaatccagt cagacaaacg
    29341 gcgctcaatt ttatcaccta accctggcgt ctcatgatgt tccgtcacgc gcgtccccag
    29401 gatagtaccg ttgaaatctg cgccaacaat aagctggata gcgccggaat agccatctgg
    29461 cgcggtggcc tcaatgatgg ccgctacggg tttatcatcc ttgcgagcga taaaaacacg
    29521 gtgtgtgcct ttgccgaggg cgggcgcatc gaccagataa cagctctctt gcagattatt
    29581 attgtaacga tctggcggca atacctgatc gaacagggca tgttgttgtt gcagcgcttg
    29641 ttcgtggatg gttgattttg tcatctgatt aatcaccgcg gtcaatcccg tagagcctgc
    29701 ggcaaaaagc gccagcgtaa taccgtgttt acgaatcgtt ttcagcatgg tttatccttt
    29761 gcgatgtcca tagacgcggg ggcgcgtgta gtagtcgatc agaggaaccg tgatattcgc
    29821 caacaggaca gcaaaagcaa cgccgtccgg atagccgccg aagctacgaa tcagccacac
    29881 taatacccca gccagcgcgc cgaaaattaa acgtccacgg ttggtcgtgg aggcggtaac
    29941 cggatccgtc aagataaaaa atgcgcccag catggtggcg cctgacagca gatgaagctg
    30001 cggcgaggcc agcgtagcgg gcgagaaaag ccaacctaac gcggcgcata gcgccagcgt
    30061 gagcagaaaa ctgaccggga tatgccagcg gatggctttt tgccacagca ggaatacgcc
    30121 gccgacaagc caggcgaggt taacccactg ccagcccacg ccagccagcg caccgctgta
    30181 tatcgggtac tgcatgattt gctcaacgga gtgcccggcg cgcaaggacg ttttaaacgt
    30241 atccagcggc gtcgcctggc tgataccgtc aataccgata cgtagtagcg tcatatcgcc
    30301 gccgctggcg gtatgcccgc taaaaatcat ccgtaacgtg tccagtatat cgggcgttgt
    30361 tgcggctatt tcataaggcg gcaaccagct tgtcatttgc accggaaagg aaattaatag
    30421 caccacgtag ccgatcatgg ccggattaaa ggggttttgt cccagcccgc catataactg
    30481 tttagcgata ataatggcga atccggttcc cagcacgacc atccaccagg gcgcgagcgg
    30541 agggatgctg accgccagca aaagccccgt caataacgcg gaataatcct gcaggtgact
    30601 ggcgaccgat tgtttgcgca gtctaaggac aatggcttcc gcgacgagcg ccgtgatagc
    30661 agccagaacg atctggaaaa gcgttcccca accaaaaaac cacgtctgcg cggcaatccc
    30721 cggcagagcg gcgattaata ccagcaacat gattcgcgat gtctggcgct ggttatgggt
    30781 ataaggcgag cttgcgattc tgaataccat ttaatcctcg ttaacaacct gctgctgtgc
    30841 tgcttttttt gcctgaacgc gagcgatagc cgcagcaacc gcggctttac gcgggtcggc
    30901 cggttcgaca ggttcgctta cggtctgctg ctcctgctta cgggctttgg cacgggcgat
    30961 cgccgcttcc accgcggctt tacgcggatc gaccggttcg gcgggttcgc ttccggcctg
    31021 ctgctcctgt ttgcgggctt tggcgcgggc gatagccgct tccaccgcgg ctttacgcgg
    31081 gtcgaccggc tcggcaggtt cgcttccggc ctgctgctcc tgcttacgag ctttggcgcg
    31141 ggcgatagcc gcttccactg cggctttacg cggatcgtcg ccggatatcg cgctgtcagc
    31201 catcggatga gcggcttgtt tagcgcgcgc ttgcgcttta cgcgcttcac gggccgcgat
    31261 gacggcgcta ttgtctggca gactacccgc ctgaataacc accggttgcg tggcctgcgc
    31321 ctgtttctct tttacccgcg ccagcgcagc ggcaatggca tcctgatctt ttgccgctgg
    31381 ttgtaccgct gcgctcttgt gacgtgcaag gcgggcggct ttttcgcgct ccagtcttgc
    31441 ctgacgagcc tcaaaacgcg ctttggcttc ggcggcgcgt ttttcttcaa gcctgatcgc
    31501 attaatctcc gctttttcct gacggaaata ttggacgagc ggaatattac tcgggcagac
    31561 ccaggcgcag gcgccgcatt ctatacaatc agcaatatgg tgagcggtag ccttgtcatg
    31621 ctgctgccct ttgctgaacc aataaagctg ctgcggtaaa aggtcggcag ggcaggcgtc
    31681 agcgcaagcg ctgcaacgaa tacagctttt ctcttcctga ggcgccccca tttcagtcac
    31741 ggatggcgcc agcaggcagt tggtgatttt tacgaccggt acgtcaagcc agggaagggt
    31801 gaatcccatc aacgggccgc ccatgatgac catctggtca gcagaggggc agaacccggc
    31861 atcgttaagc aaatgacgaa cgggagtgcc gagccgcgcc cagacgttac ccggacggct
    31921 tatcgcttca cccgttaagg tgacgacgcg ttctgtgatc ggttcgccgt caaccacggc
    31981 gcgtttcacg gcatatgccg taccgacgtt ttgcatcagc acgccaatat cagaggagcg
    32041 cccgccgtgg ggaacctgtt ttcccgtcag tatttgggtg agctgttttg cgccgccgga
    32101 agggtatttg gtcgggataa cacgtaatga aatatcatga gcgtcagcca gtacggcgcg
    32161 cagcatggaa atagcctgcg gtttgttatc ttcaatgccg attaatacct cacgcggttg
    32221 cagaatatgc gccaggatgc gaataccttc cacaatctgc gcggcgcagt cctgcatcag
    32281 acgatcgtcc gccgtaatgt aaggttcgca ctctgcggca ttgataataa gcgtggtgat
    32341 tttatcgtcg ccgccctgca atttaacgcc ggtgggaaac cctgcgccgc caagcccggc
    32401 aacgccatac tgatgaatgc gttcaatgag cgcttcacgg ctgtgggcgc ggtaatcaga
    32461 ccagccctcg cgttcaatcc agcggtcctc gccgtcggca tcaatgatga cgcttaactc
    32521 cgccagcgcc gaaggatgcg ccgtcgagtg gggcgcaata gcgataaccg tcccggaggt
    32581 gggcgcgtgt accggcagca ttctcccacg tccacgggta agcgcctggc cgcgtagcac
    32641 gcgatcgccg acgctaacgc acagctcgcc ctcagcgcca atgtgctgtt ttaaagggat
    32701 aacaaagcgc ggcgccaaag gcacctggcg cagcggcgtg ccgtttgact gggacttcat
    32761 ttcgggcgga tgaataccac cgtcgaaatc ccagatttta tcttttctga aagcggaaaa
    32821 tagtttaagc atgttgttcc acgggaatga tgcgaacggg aatggtgttc aaatcccatt
    32881 tccaactgtc gggcgtctca ttcaccggac gtaattcgat gcagtgcgtc ggacacggat
    32941 cgacgcacag attacagcca gtacagagat cgctcatgac cgtgtgcatg gcgcgcgttg
    33001 cgccaacgat ggcgtcaacc gggcaggcct gaatgcattt tgtgcagcca atgcagttat
    33061 tttcatcaat aactgccagc atacgtactg gcgcggcctg ctgttcttca ccatcgcatg
    33121 gttgcggctc tacgtttagc aactctgcca ttttcagcat gacggcttcg ccgccgggcg
    33181 cgcaacgatt gattttctcg ccctggagac ccacggcttc ggcgtagggg cgacagccgg
    33241 gatagccgca ctgaccacac tgactctgcg gcaaaatcgc atcgattttt tcaacaaccg
    33301 gatcatcttc aaccgcgaat cggcgggagg cataacccag aatggcgccg aacaccagac
    33361 ccagaagggt cagggcgcca acggcaatcc agatagtatt cattacaact tcaccaaacc
    33421 actaaagccc ataaaggcca aagacattaa tcctgcggta atcaatgcta tcgcgttacc
    33481 acgaaaaggg gcgggcacat ccgccacggc aaggcgttcg cggatagcgg caaacagaac
    33541 catcactaat gaaaaaccga cggcggcgga aaatccgtac agcgccgact gaagaaagtg
    33601 atgaccgaga ttaatattca gtaacgctac gcccagaacc gcacagttag tggtaatcag
    33661 tggtaagaag atgcctaaca agcggtataa cgccgggctg gttttccgca caaccatttc
    33721 ggtaaattgc acgaccacag caatgacgag gataaaggcc agcgtccgca gataaatcag
    33781 atccagcgga ataagtatcc aggtgtcgat aagccaggcg catatcgacg ccagcgtcat
    33841 gacaaaggtc gtcgcgaggc ccatccccat ggcggtttcc agttttttgg atacgcccat
    33901 aaagggacaa aggcccagga atttgaccag tacaaagtta ttgaccagta cagttccgac
    33961 aaagagcagc aggtaatcag tcatgtttcg gcctgaaata aaaaagccgc ctattatctg
    34021 tcaaactacc acaggcgaca acaggttaac tgtagggtta ttacggatta acaaacgttg
    34081 ttttaacgcg cgctgaacgt ttgagataag gcacaatgag cgccgtcgcc aacagtggga
    34141 agagtaactg acgcacggca aaggcatctg agacgggcga aaaggcaaat gctttaaccg
    34201 ccagtaacac cgacaccagc agccagataa tgtaatgctt tggcacgcag cgtctgcgct
    34261 tgaagaatgc gatcgtcaac cacaaggtat agtaccacat ggcgatagcg gtaataaatg
    34321 aaatgcccca tagcagtaaa ttaccggttt cctgtccgct aagcgttttg aacgtttgcg
    34381 gtgtggcaag cgccataacg tagagtaata acgccagcga ggcgctcaac aacgcgacta
    34441 acagccaggc taacgggcca agaagccagc ctccaattcg ttgtggcggt gttgtagtca
    34501 tatcttctcc ggggttacgc gcgttaacgg tcatgccgct cattttgggg caaatattat
    34561 aaggtttttg atgttaaacg ctactttctt tattgcacat agcgccagac ggattgcgga
    34621 acctgaccta catcaaacag gcgtcctccg gaaaccagct cggcacggcg gtgatctgca
    34681 gcgcgataca tattaacgat gtccatgtca tcagtaaggg tatagttaag gtggtcgaac
    34741 agtttttcca gactttcgag cgaactaatt ttgcggaatt ttaatagata atcctgaaca
    34801 gtcatataaa gttgatccat attaaatata atgccaacgg agtagtcact gataaaaaaa
    34861 taaacaaaat tgcaccagtg agaggtcagg ggtgcaggta aaaagggaat attcttaccg
    34921 gtaaagagtc aggcgccaca tggcgcctgg ggcgaaaggt taacgcgctt tactacaaca
    34981 ggcaataaac gtcagaccag atagaacata tttcgttttt tttgccggtt tttgactttt
    35041 ctttgcacgc cccggggcgc tgcttaccgt accgcgcgaa aatgccttta cattatctga
    35101 cgcttacttc ttctgaacgg aagccgtggg ctcaggtggt tggtaattgt caatatggtt
    35161 ggcaatacct aaaagaatga ctgagataat gagaactatc cacccagtta attcaataag
    35221 acgattcatt attgacgaca tttgctttga tttatccata aacacagaga gtaaatgtta
    35281 ctttcctggc gaacggtcgg caagagggag gggaacgatt tcagcctctg ttctgtaaca
    35341 agttaatcat ttgatgctac gttgatggtc aggacgctat tgcggctagt cgcacgatgg
    35401 tgtggaatag cgatatctaa aaccggaggc agtgagatga atgacaaaat ccgcgttggg
    35461 ttaatcggtt atggctacgc cagtaaaacc tttcatgcgc ccttaattat gggaacgcca
    35521 gggttagagc ttgcggcggt atccagcagc gatgaaacaa aagtgaaagc agactggccg
    35581 gcggtctccg tggtctctga gccccgacat ttatttaacg atccgcatat cgacctgatc
    35641 gtgatcccga cgcccaacga tacccatttc ccgctggcga aagctgcgct ggaagccggt
    35701 aagcatgtgg tggttgataa accctttacc gtgacactgt cacaggcgcg agaattggat
    35761 gcgcttgcgc ggagcactgg tcgggtactt tccgtcttcc acaaccgacg ctgggacagc
    35821 gattttttga cgctgaaggc cttgctggcg gatggcgtgc tcggcgaggt gtccttgttt
    35881 gaatcccact ttgatcgctt ccgtccccag gtgcgcgacc gctggcgcga gcaaggcggg
    35941 ccgggaagtg gtatctggta cgatctggcg ccgcacttgt tggatcaggc cattcaactt
    36001 tttggcctgc cggtcagcat gacggtggat ttagcgcaac tgcgtccggg cgcgcaatct
    36061 acagattatt tccacgcgat tttatcctac ccccagcgcc gcgtgatttt gcacggtacg
    36121 atgctggccg cggcggaatc cgcgcgatac atcgttcatg gttcgcgcgg tagctatgtt
    36181 aaatatggcc tcgatcccca ggaagaacgg ttaaaaaacg gcgagcgttt accgcaggaa
    36241 gactggggat acgacatgcg tgacggcgta ttgaccctgg ttgagggaga gacgcgcaaa
    36301 gaagagaact ggcttacgtt gccgggtaac tatccggcat attatgccgc catccgcgat
    36361 gcgttaaacg gtaacggtga aaatcccgtg ccggcaagcc aggcgattca aattatggag
    36421 ttgattgaac tgggcatgga atcggcaaaa catcgcgcga cgctgtgtct tgcctgagat
    36481 gtcgcatttc tccgcctggg atagcattaa accgcaggcg gagaagagcg ttagtgtcaa
    36541 taaagcaatc ttacgccgcg gccacttttt cgcgtagcgc acgtttttcg ctatcgctca
    36601 gaaaggcgat ttccagaccg ttaatctgcg cctggcgaat ctgttcgcgg ctcaatcctg
    36661 ccgctggcgc ggcgacgtga tattcatgga taatatctac gccctgaaca gccggatcgt
    36721 ccgtattaag actggcgaga acgccatgct caaggaaggt ttttagtgga tgatccgcca
    36781 gcgatgcgac ggtactggtc tgaatattcg aggtcagaca ggattcaata ccgatacgct
    36841 gctgtgcaag aaaatccatt aacgcgcgat cttcgacagc ttttacgcca tgtccgatac
    36901 gctcggcccc cagttcgcga atcgtctgcc agatactttc cggccctgcg gcttcgccag
    36961 cgtgaacggt aatatgccag cccgcatcgc gcgcccgatt aaagtgcgac aaaaacagac
    37021 tgccgggaaa gccaagctca tcaccggcta aatccagcgc ggtgattttc tctctgtgcg
    37081 ccagcagcgc atcaagctcc tgtaaacatg ccgcctcgcc gaaggtacgg ctcataatgc
    37141 caatgagtcg tgcctcgacg ccaaacgtgt tacagccgtc gcgtacaccg tcgataacgg
    37201 cttcaaccac gcctgcgatc ggtaactgat gcgccatcgc catatagccg ggcgaaaagc
    37261 gaagctcgac gtaatgcagg ccgttacgtg ccgcatcttc aatattttca aaggccacac
    37321 ggcggcaggc gtcaagcgat gccaggactt ttacccccca atcgagttta gtgagaaagc
    37381 ttactaaatc gggttcggtt gaggtgacct ggacatgcgg aatcagcgtt tccagcgttt
    37441 gggcgggaag ggcgatgttg aactgccgac caagatccag aattgtttgg gcgcgaatgt
    37501 tgccatcaag gtggcggtgg atgtcagtca aaggaagcgt aatatcaatc atgggcgcac
    37561 tcaattttta ataaaagtgc gcaccattat actacagatt gataatgctc tggaaatttt
    37621 gcaaaaacgg agtcattacg ttgcaacttc gcgagagcgc gggagaaatt ttgtatcatt
    37681 ctctgtaacg cgcccccggt cagctcacgg gggttgtctc tgttatcgcc tctcaggata
    37741 aagggtcaac cccccgcttg tagacggtat cagcgaacgg cgcggtggca aaatccatat
    37801 ccgagatcgt aaaggggagc agatcggctt cgccaaaacg atcggcgaca taatcccact
    37861 acgtacacca tgtcccgcgt cggtcaactt cctgtgaaaa atcgaacata tcccttcctt
    37921 atgcctgaac ggtattcatc aggccaacca tttcatcttt taccgactga acctgcgggc
    37981 cgataattac ctgcaaatta tgctgattga gctgtacgat gcctgtcgcg tgattgtcct
    38041 tcaatgcctg gacatcgaca aacgacatat ctttcactga caggcgtagg gggggatgca
    38101 gttgtccaga ctcacgatgt tttccgtgcc gcctaatgct cacgacgagc accatgtgcg
    38161 gagtcaaacg atagccgctc gcctggtaac gcaaaagtag aggctgcgcg tcgttcggcg
    38221 cagaccgggt gcagcgtcgc gacacccggc aaggcgatta ttgttgaggc agcgccggaa
    38281 cgtccggaac ggaaagcgcc ggcatcccaa ataggccgac aaagtcttcc aacggcattt
    38341 tttgtccgtt gagcgtgatc tggccattgg cgtactgcaa actggaggcg atagtattat
    38401 ccttcagcgt tgtcagtcgg aacatctgac ccattgcgga cagcccctgc acctgctgtt
    38461 ttgccagttt ttccgcatca tcctgctgat agccttccag ttttgctatc tgcgtcataa
    38521 actcgaccgc catgtccatc ggaattgcca gtttcgcatc cagcgatttc acggagcggt
    38581 cgacttcctg tgccagcgtt tgcggttgtg ccgttgtggt tgccggatct ttgaggaaca
    38641 gcgacagatt cagcgtggtt tcccctttgg cgtttttcca gctaagcggc gccagggtca
    38701 gaaccggatc gccttttaac agcacgggga gagcgctaaa gaacgcttca gtgacttttt
    38761 gctgataaag ctcaggattc tgcgccacgt ccggctgatt cagcagcgcc tgcgtttgcg
    38821 catgatattg ctgactaaac tggtgccagg cttcgccgtc gatttgaccg actttcagcg
    38881 ttaatttacc gctgcccaaa tcctgattct gcactttcag gctgttaagc gagtaatcca
    38941 actggctgtt aatggttttt ccgtcgttga cgagatcgga cttgccggca atttccatcc
    39001 cttccagcac cgccatctct ttaccctcaa tggcgatgga cagtttatcc agcgttaact
    39061 tttggtcgcc tacacgctcg ccaaagcttg ccagcttact ggtaccgtct gttttcaaat
    39121 tattaaaggt gagttgtacc ttctgattat attcgttaac ggcatcgacc aggccgctct
    39181 gcgcttcgcc cgacagcgaa accacattac cgtctttatc ggcgttaagc tggaactcgc
    39241 cgccgctaaa ggcgaccttt tcaccggcat tctcgtagtt taacggcttg agagagatat
    39301 cggagcgggt atcgccgcca taaccaatgc gggtattgat aacaaagggc gcgtcgcctt
    39361 tcgcaatatc aaagaggggt tttgccgcat cgttattcac cagagtggtt tttaccgacg
    39421 ccatagaagg gatcagattg agcgttttga gctgggcgag cgggaagggg ccatgtgaaa
    39481 cggactcgtc cagcacaatg ctttgcccgg gcttcaacca ggtattgtct gcgccggcaa
    39541 ccggtttgac aaccagttgc agatggctac tgaacacgcc gcgctggtag ttttgataac
    39601 ttaattcgac accggcctcc ggcgcagtac gcttgagctg ttcattggcc tgagtcacca
    39661 tttctgcaag atggttctcc agctttttcc ccgtatacca ggcgccgcct gtccagacga
    39721 tgccaagtgc aattactaca cctgcagcta ccagtgtttt tttcatatca attgtccata
    39781 aaaatgaaac caggcggatt aaaccgcctg gaggagtttt acgtctgtta taagcttagc
    39841 aagagttgtt aaaaaattca gtacgttgct acagcttgtt ataaacacgc gctaaacggc
    39901 ccgtgccgct ggcgttaacc ggagactcat ccgcgccgat aaaggcagat tcacccggct
    39961 tcagtaccag acgctgttca tctttacgta acaccgcctc accctcaacg cagaacagaa
    40021 tcgcggcgct gtgttggccg atgctcgtct cctgaagcgc caggtcgtgc agtgaaaaag
    40081 caaaatcgtc aaccggaatt gggaagtcca gctccgcgcc gcttttcacc ggggcagtca
    40141 gcaactcgcc ggcaggctta ggttcgaact tcacgttcgc gaccagctca gggatgtcga
    40201 tatattttgg cgtaaggcca gcgcgcagaa cgttatcgga gttcgccatg acttccagcg
    40261 caacgccctg cagataagca tgaggcgttt cggcaaacag gaacatcgcc tcgccgggat
    40321 tcagtttgac cacattcagc aacaaaggag agaaaagccc gctgtcgtca ggataatact
    40381 ctgaaatcac gcggatcgtt tgccacggtt cgccttgctg gctgttaagc gccgctttga
    40441 gtacggctaa cgcgcgggat ttttcttcgc cttgcatatt caacaggctg gcgaaaagct
    40501 ggctcagacg ttcagcattc ggcgcctgca aaaagtgggc gatagcggaa tgcgcgccgg
    40561 cgacaggttg cagtaaagag acaatgtcag aaaattcgcg gaacgcgttc atcgccagga
    40621 aaggcgccag ggcaaaaacc agctctggtt tatggttagg atctttatag ttccgctctg
    40681 cggcatccat ggggataccc gccgcatttt ctttcgcgaa accgatttcg gaattgcgct
    40741 tattcgggtg cacctgaata gagagcggct gcgcggcgca cagtacttta aacagaaacg
    40801 gcagttcgcc gaaacggttg gctaccgctt cgcccagcat ggcggtttta ttcttttcga
    40861 tggcgtcacg cagggagacg gtttcgccgt tggcggtggt gattcgcgag ctgcttttgg
    40921 gatgcgcgcc catccagagt tcagccattg gctgctgctg cggattggcg atgccataaa
    40981 gttccgttaa cgcagtttta cttccccagg catagttttg cactgagtta atgagttttt
    41041 gcattatcaa gccctgtttc aatgtggaga tcaatgggag gtattaaacc aagaaacccg
    41101 catgaagtaa cctccgggcg taaaaagtcg tacttgtctc agtttttgtt aaaaaattgt
    41161 gtaggatagt gtaactcgct ttgagtcggg caatggaaca cctgcccaga gaataaccat
    41221 accgagcggt aagtgagagc acaatgtcaa acaaaccctt cttttatcaa gacccttttc
    41281 ccctcaaaaa ggacgatacc gagtactact tgttgaccag cgaacatgtt tccgtcgccg
    41341 agttcgaagg acaagagatc ctgaaagtcg cgccggaagc gctaacgttg ttggcgcgtc
    41401 aggccttcca cgatgcgtct tttatgctac gtcccgcgca tcagcagcag gtggcggata
    41461 ttctgcgcga tccgcaggcc agtgaaaacg acaaatatgt cgcgctgcaa ttcctgcgaa
    41521 actccgatat cgcggccaag ggcgtgttgc ccacctgcca ggataccggt acggccatta
    41581 ttgtcggcaa aaaaggccaa cgcgtctgga ctggtggagg tgatgaagcg gcgctggctc
    41641 gcggcgtata taacacctat atcgaagata acctgcgcta ttcgcagaac gcggcgctgg
    41701 atatgtacaa agaggtcaat accggtacta acctgccggc gcagatcgat ctctacagcg
    41761 tcgatggcga tgaatataaa ttcctctgta tcgctaaagg cggcggttcg gcgaataaaa
    41821 cctacctcta tcaggagaca aaagcgctac tgacgccggg taagctcaaa aattatctcg
    41881 tcgataagat gcgtacgctg ggcaccgccg cctgtccgcc gtatcacatt gcgtttgtca
    41941 ttggcggtac ctcggcggaa gcgaacctga agaccgttaa gctggcctcg gcaaaatact
    42001 atgatgcgct accgaccgaa ggcaatgaac acgggcaggc cttccgcgat attgagctgg
    42061 aaaaagaatt gttgcttgag gcgcaaaatc ttggcttagg cgcgcagttc ggcggcaaat
    42121 atttcgctca cgatattcgt gtcatccgat tgccgcgcca tggggcatcg tgtccggtag
    42181 gtatgggcgt gtcctgctcc gcggatcgaa acattaaagc gaagatcaac cgggaagggt
    42241 tctggatcga gaagctggag cgcaatcccg gtaaatatat tccagaggcg ctgcgccagg
    42301 cgggagaggg cgaggcggtg cgcgttgatc ttaaccgtcc catgagcgag atactgcaac
    42361 aactgtcgca gtatccggta tcaacgcgct tgtcgctgaa cggcacgatt attgtgggcc
    42421 gcgatatcgc gcacgctaaa ctgaaagaac ggatggacag aggcgaaggt ttgccgcagt
    42481 acatcaaaga tcatcctatc tattatgcgg ggccggcaaa aacgccggaa gggtacgcct
    42541 ccgggtcgct tgggccgact accgcaggac ggatggactc ttatgttgat cagctccagt
    42601 cgcagggcgg cagtatgatc atgctggcga aaggcaaccg cagccagcag gtgaccgatg
    42661 cctgtaagaa acatggcggc ttctacctgg gcagtatcgg cggcccggca gccgttctgg
    42721 cgcagggcag tatcaagcgc ctggagtgtg tggaatatcc tgaactgggt atggaggcta
    42781 tctggaaaat tgaagtggag gattttccgg cctttattct ggtggatgat aaaggtaacg
    42841 atttcttcca gcagattcag tcatcgcagt gcgcgcgctg cgttaagtaa tgtcgccgcc
    42901 ctgcggggcg gtaacatgat tcgctatttt gccggagaac ggcgcaagcg ccttatccgg
    42961 tctacaccgt tgtgttgtta tcgttaatac tcataagacc gcaaacatgt gagcaatgtc
    43021 gacacatgat ctcatcaact tgagtaagga gcaggtaatg gtaacggtac gccgcgagaa
    43081 agattcaatg ggcgtgattg aagtcccggc agataaactg tggggggcgc aaacgcaacg
    43141 ttcgctggag cattttcgga tttccacgga gaaaatgccc gtctcgctca ttcacgctct
    43201 ggcgttgacc aagcgcgccg ctgcgaaggt caaccaggac ttagggttgt tggcggcgga
    43261 aaaagccagc gcgattatcg aggcagctga tgaagtgctg gcgggaaaac atgctgatga
    43321 gtttccgctg gcgatttggc agaccgggtc cggtacgcaa agcaacatga atatgaatga
    43381 agtgttagcg aaccgcgcca gtgaaatttt gggcggcgtt cgcggtatgg aacgcaaagt
    43441 gcatcccaat gatgacgtca ataagagtca aagctcaaac gatgtgttcc caaccgccat
    43501 gcacgtggcg gcgttactgg cgttacgcga acaccttatc ccgcaattat ccgcattaac
    43561 ggatacgctt cgcgataaat cccacgcttt cgccgatatt gtcaaaattg ggcgtactca
    43621 cctgcaggac gcgacgccgc tcaccttagg ccaggagatt tccggttggg tagccatgct
    43681 ggaacataac ctcagacaca ttgagcacag tttaccgcac gtcgcggaac tggcgctcgg
    43741 cggaaccgca gtagggacag ggcttaatac ccacccggaa tatgcccggc gcgtggccga
    43801 ggaactggcg accattaccg cggcgccgtt tgttaccgcc ccgaataaat tcgaagcgct
    43861 ggcgacctgt gacgcgttgg tacaggcgca tggcgcatta aaaggactgg cggcctcgct
    43921 gatgaaaatc gccaacgatg ttcgctggct ggcatccggc ccgcgctgcg gcattggcga
    43981 gattgctatc ccggagaatg agccaggcag ttccattatg cctggtaaag tgaacccgac
    44041 ccagtgtgaa gcggtaacga tgctatgttg ccaggtaatg ggtaacgatg tggccatcaa
    44101 tatggggggc gcatcgggca actttgagct caacgtctat cgtccgatgg ttattcataa
    44161 ttttctgcaa acggtgcgcc tgctggccga tggcatggcg agtttcaatc aacactgtgc
    44221 gtcaggaatc gagccaaacc gcgagcgtat tacgcagttg ctgaatgagt cgctgatgct
    44281 ggtcactgcg ctcaatacgc acatcggtta cgataaagcg gcggagattg cgaagaaggc
    44341 gcataaagaa gggctgacgc tcaaagcctc agccgtggca ttaggatacc ttagcgacgc
    44401 ggagttcgac gcctgggtac gtccggagtt aatggttggc agtatgacgc cgggacgtta
    44461 atccgccaca tacaggtgca gtcgcggaat aatcagtcgc agcggctgcg cctgtggttt
    44521 aaaacggtgc tgaatattat cggcgtcata gttttccagc ccgccaatat ccggcacgcc
    44581 agcgccgttg tccgtgttga ttaatgcgat aatcggcgag gggcaggcgt gttgcacctg
    44641 tttctgctgg cctttatacc agatgcgggc gatcggctgt accttaaccg ggcgcttaat
    44701 cttgagtttg gcctgctgcg gtaaggcagc gatatcctga tattcccgtt ccagcttgaa
    44761 ttgccattgt tcgcgcgtcc acggcgggac gctgcgcggc gacgcgaggc tttttttcaa
    44821 ctggctcaga acctcatccc ggcttaaatt tttaataata tgtttatttg cccaaccgaa
    44881 acgtatggtg gcggggttat tgataagcgt cagcgtgcgg taagcgttca gcgtaattaa
    44941 gccgggtaga tgccgatgca cccactcaaa acgtgccgct gagggaagac cggactctac
    45001 cgtaaccatc tgctcgaagg tggttttcaa ctggttaatg cgctgtacct gattttccag
    45061 atctaactgt gtcgcattat ccacttgata gcataaaacg ccaggcaggc ggacggcggc
    45121 tttactgctg cggttttcgg actgctgttg aataaacaaa tggcgatagt gacgtagcgc
    45181 cagcgcttcg gcctctttcc ccagatgttg cgtgacctcg atagtgtcca gcggcgcatg
    45241 ttccgcctct ttggtcacct gcggcagtga aaagacacta gcgataagta gcgaatgctg
    45301 ctgtagatta tccgacagcg ccgccaggtg ttgttctatc tggcgaaaag tgccattcag
    45361 gcgttcaacg agatcgtagc gggacatggt atcactcact ttagttacaa catactatct
    45421 gtatagcaca attcccgcgg ctcaaccagc gtgcaaaata cgtcaggccg cggtcatgtc
    45481 gggcatcgcg tgccagaccg gccagcgaaa gctaaatttt gcgccgccca gttcgctatc
    45541 gtcacagacg acgctaccgc ccatcgccag agcgatagag tgtacgatgg cgagtccaag
    45601 cccgcagccg cctgtcgccc ggtctctact ggggtcgagt ctgacaaaag gttcaaatac
    45661 gcgctctcgc gcatccgctt caatgccggg gccatcatct tcgactatca gcgttgcctg
    45721 actgccgtca agtaacagac tgacctgaac ggtggtacgg ctgtagcgca acgcattatt
    45781 cagcaggtta tccagcactc gcgacattaa ccgcatatca agcgcgccat aatcgccgat
    45841 tacacatgtg agaagattta cggcgcgttc cgggttcacg ctctgcacat cctgcaaatg
    45901 cgcgaacaac caggcgggga ggtcgggttt ggtcaacatc agttcatttt gtggtcggtc
    45961 aaggcgcgca taggtgagca gttcttcaat cagcgcttcc agttgaccaa tatcgcgatt
    46021 gagcgcctgt gattccggcg gagtcagatt ttcactcatt tcaagccgat agcgtaaacg
    46081 taccagcggc gtgcgaagct catgggcgat accgtcaatc agctgttttt tactggcgat
    46141 cagagcatta atgttatccg ccatctggtt gaacgcgacg cccagacgtt cgaaactgga
    46201 accattatcg aaatgcaggc gttcagtcaa atgaccctcg ccaaagcgct gcgcggcgga
    46261 ttcgagcctg agcatttctt gccagtgcgg gcgcatccag ataaacacag gaaaggcgag
    46321 agaaaaggca atgagcgcca ttaaggcgat atccagcagt cgcatttgat gcaggaaata
    46381 gagataggga accgggccaa ccgccaggac gtaatggctg cgcgggatac gctgaataaa
    46441 ggtgtattga tcgtcaagcg cgacaatatc gccttcacgc agtcgctgcg tggtggcggc
    46501 atcaagctta tagtgattta acggttcaac gcgtaaatcg aaagagaggt tcaggtccat
    46561 ctcttttaac gttttccccc attcacgcgg cggaatttcc cgcagttcgc tgcgcatcag
    46621 atagagcgaa cttttcatca gatcgtcgag cgattgcctg cccgcgcgtt cggcagtgaa
    46681 tttgtacacc agtccgacca ataaggtcat gaccagaaaa cagacgaaca gcaaaaggta
    46741 aaactgcaca aacagctttt tcatcaacgc ccaccggatc tcaatacatt agctctatcg
    46801 cgcgctgacg gaaaagattt cccgtcagcg ccgctggtgg gttataaaag caggctttgc
    46861 gtcaactgac aacctcattg tccggcgtta aggtccggac tttcgtgaac aatgcgtcca
    46921 tcgacaagcg tcaaaacagc gcgaatggta tcaattctgt cttccggcat cgtcataaag
    46981 ggctgattga gcaccgccag atcggcctgt tttccgacgc taagctggcc ccggtgttgt
    47041 tcggcaaagg cgagccaggc ggcatgacgt gtatataacg ctagcgcttc cagacgcgtg
    47101 agccgctcgc tggcgggttt acgcacggaa ccgcctgacg ctataccggt gatatgatat
    47161 tcgatagcgt gccagacacc ggcaatgcca atacgcgtcg aatcggtgcc gccagctacg
    47221 acaagccctt tatccagcgc cagtcgaacc ggcggcgaat tgtccgtcgc accgggtggg
    47281 ttggcgtcac ggatggcaag cccctcaaag taaggcccca tttgcacagt gtatgccaga
    47341 cccagcttac gcattcgctc aagtgtctgt ggcgaaccgg tattcagatg cgcaatagac
    47401 cagcggagag ggcgcagatc gtactgctgc gctacctgct caaaaatcgt caatatcgcg
    47461 tcggcgctgt catcggtata ggcgtggatc tcaagcggta ttccccgttt tgccgcaaac
    47521 gtcgcgacct ggcgaagcgc ggttttgtcc tgctctgagg aagaaaaccc tggggccatc
    47581 cgcacgccgt cattcattcc tgccaccagg ctttccccca ggccaagaaa agccagttgc
    47641 ccgtcgtcgg cacgcgccgg gcgaaaggcc atcaggttgc tgaaccactg cgcttcatga
    47701 cctttcgctt ccggctgtac cggaatgcga taccccacgc gcagcggtaa atccccctgg
    47761 tttcgcattg caaataaagg ctcataagcg gcggcaggcc cggcagaggg gtcaatgatg
    47821 ccggtcacgc cgcgagcgtt catatcagcg aaaaattgtc gcagaccgcc ctcgcgatcg
    47881 gcgttactac ttatgctggc aaaaagctgg ttaaacgcgg cgatgtcacc aaataatttc
    47941 cccgtggcgc taccttttgc gtcgcgctct acgcggattc ccgctaaatc aggaggaggg
    48001 gtgtcgttaa ggccaagtac gtctataccg cgctgattca ctaacgcata gtcgtaaaga
    48061 tactgaatat aagccggatg atcgggaagg gcgtggctca gttcggctac cgtcgacgcc
    48121 cggttttctg caaattgcgc cggtatccat gatcccacta cggctaccca ttgatcgtgg
    48181 ggacgacggt tagcgtcggc gcgtaattta tccagcgcgt ctttaagcga agggctgtcg
    48241 taccagtagg tttcgaatgt ccaggtttgt ccgccgcgaa tggcgtgaat atgggtatcg
    48301 gtcaggccgg gtatcacggt tttaccctgt aaatcgatgg tacgggtatg gtcgccgcgc
    48361 cattcatttg tcgccgtatc atcgccaatc gccacaatcc gcgagccgga aatcgccagc
    48421 gcgctggcct gcggctgggc atcattcaga gtgatgatat taccgttatg caaaataata
    48481 tccgctgccg ggcgggcggc ggtggctgcg cctgtggccg tgagcagaaa gagaagcgcg
    48541 gttctggaaa gcagaggcgg gacgagactg atcattagca tgttcctttt gtcgggagat
    48601 aagcaaacca tagagagcga acaagaattg ttcaatctgt gcccagggaa cagtgcgttc
    48661 tgtttttaga acggtggtga tagaaaaaga aaagcccgcc gaaacggcgg gcttgagaag
    48721 aattaatgaa taattagaac tggtaaacca tacccagcgc gacgatatca tcagtgctga
    48781 taccggcatc tttatagaac gggtcgtcgt catccagcag gttgatttta taatcaacat
    48841 aggtggagaa gtttttgttg aaatagtagg tagcacctac atcagcatat ttaaccaggt
    48901 ctttatcatc gccattaacg ttgttatagg tcagatcttt acctttagac atcaggaaag
    48961 aaaccgccgg gcgcagaccg aaatcaaatt gatattgggc tgtaacttcg aagttttgcg
    49021 ttttgtttgc tacgccgcca tcataaccct tgtccgtttt accataaggc gtcatattac
    49081 gggtttcaga atacatagtc gctaaataga tgttgttggc atcatatttc aagccagctg
    49141 tccatgcatc cgctttgtcg ccgccagcaa tcgtgccgcc agcattgact tgctcattag
    49201 tacgatcgga agtggtatac gcagcgcctg cgctgaagcc catgccaata tcataggtag
    49261 tagaaatacc gaagccatca ccgttatcgt aacgaatatc gtcgccatta ttacggttat
    49321 tggtaccgat atttacatcg tcagcgcttt ggctttcatt tttaccctga tattgcaacg
    49381 cgaagttcag accgtctacc agaccgaaga aatcagtgtt acggtaggtg gccacgccgt
    49441 tagcacgacc ggtcatgtag ttgtcagcgt aagtatagga gtcgccgccg aactcaggca
    49501 gcatatcggt ccagccttcc acgtcgtaca ggacgccgta gttacgacca tagtcgaatg
    49561 agccgtagtc gccgaatttc agaccggcga atgccagacg agtccaggag ttcgcgcctt
    49621 cgccttcggt agtgttagcc tgaacgttat attcccactg gccgtaaccg gtcagttggt
    49681 cgttaatctg cgtttcgcct ttaaagccga cacgcatata ggtctgatcg ccatctttag
    49741 aagagtcatc agagaaatag tgcaggccgt ctactttccc gtaaaggtcc agtttgttgc
    49801 cgtctttgtt ataaatttca gcggcgtgtg ctgcgccagc agccagcaga gccgggatga
    49861 caagtgccaa tacttttctt ttcatttttt tatccttaaa aacttaactt atttgcaaaa
    49921 gattgaactt ct
//
LOCUS       DAJVBX010000010        49074 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.010, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000010 DAJVBX010000000
VERSION     DAJVBX010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 49074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49074
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.010"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..713)
                     /gene="rlmB"
                     /locus_tag="OPV72_000513"
     CDS             complement(<1..713)
                     /gene="rlmB"
                     /locus_tag="OPV72_000513"
                     /EC_number="2.1.1.185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HCR9912902.1"
                     /translation="MSEMIYGIHAVQALLERAPERFQEAFILKGREDKRLLPLIHALE
                     SQGVVIQLANRQYLDEKSDGAVHQGIIARVKPGRQYQENDLPDLIALHDRPFLLILDG
                     VTDPHNLGACLRSADAAGVHAVIVPKDRSAQLNATAKKVACGAAESVPLIRVTNLART
                     MRMLQEENIWIVGTAGEADHTLYQSKMPGRMALVMGAEGEGMRRLTREHCDELISIPM
                     AGSVSSLNVSVATGICLFEA"
     gene            complement(804..3242)
                     /gene="rnr"
                     /locus_tag="OPV72_000514"
     CDS             complement(804..3242)
                     /gene="rnr"
                     /locus_tag="OPV72_000514"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HCR9912903.1"
                     /translation="MSQDPFQEREAEKYANPIPSREFILEHLTKREKPASREELAVEL
                     NIEGEEQLEALRRRLRAMERDGQLVFTRRQCYALPERLDLLKGTVIGHRDGYGFLRVE
                     GRKDDLYLSSEQMKTCIHGDQVLAQPLGADRKGRREARIVRVLVPKTSQIVGRYFTDA
                     GVGFVVPDDSRLSFDILIPPEDVMGARMGFVVVVELTQRPTRRTKAVGKIVEVLGDNM
                     GTGMAVDMALRTHEIPYIWPQAVEQQVAGLKEEVPEEAKVGRVDLRDLPLVTIDGEDA
                     RDFDDAVYCEKKRGGGWRLWVAIADVSYYVRPPTPLDREARNRGTSVYFPSQVVPMLP
                     EVLSNGLCSLNPQVDRLCMVCEMTISAKGRLTGYKFYEAVMSSHARLTYTKVWHMLQG
                     DQDLREQYAPLVKHIEELHNLYKVLDKAREERGGISFESEEAKFIFNAERRIERIEQT
                     QRNDAHKLIEECMIMANISAARFVEKAKEPALFRIHDKPTTEAITSFRSVLAELGLEL
                     PGGNKPEPRDYAELLESIADRPDAEMLQTMLLRSMKQAIYDPENRGHFGLALQSYAHF
                     TSPIRRYPDLSLHRAIKYLLAKEQGNKGNTTETGGYHYSMEEMLQLGQHCSMAERRAD
                     EATRDVSDWLKCDFMLDQVGNVFKGVIASVTGFGFFVRLDELFIDGLVHVSSLDNDYY
                     RFDQVGQRLIGESGGQTYRLGDRVEVRVEAVNMDERKIDFSLISSERAPRNVGKTARE
                     KAKKGESKNAGKRRQVGKKVNFEPDSAFRGEKKAKPKAAKKDARKAKKPSAKTQKIAA
                     ATKAKRAAKKKAAE"
     gene            complement(3280..3705)
                     /gene="nsrR"
                     /locus_tag="OPV72_000515"
     CDS             complement(3280..3705)
                     /gene="nsrR"
                     /locus_tag="OPV72_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005134424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide-sensing transcriptional repressor
                     NsrR"
                     /protein_id="HCR9912904.1"
                     /translation="MQLTSFTDYGLRALIYMASLPDGRMTSISEVTEVYDVSRNHMVK
                     IINQLSRAGFVTAVRGKNGGIRLGKPANTICIGDVVRELEPLSLVNCSSEFCHITPAC
                     RLKQALSKAVQSFLKELDNYTLADLVEENQPLYKLLLVE"
     gene            complement(3925..5223)
                     /gene="purA"
                     /locus_tag="OPV72_000516"
     CDS             complement(3925..5223)
                     /gene="purA"
                     /locus_tag="OPV72_000516"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019842885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HCR9912905.1"
                     /translation="MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTL
                     VINGEKTVLHLIPSGILRENVTSIIGNGVVLSPSALMKEMKELEDRGIPVRERLLLSE
                     ACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAE
                     KLKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDF
                     VMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGA
                     GPFPTELFDETGEFLCKQGNEYGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLD
                     VLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGL
                     PQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA"
     gene            complement(5326..5523)
                     /locus_tag="OPV72_000517"
     CDS             complement(5326..5523)
                     /locus_tag="OPV72_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2065 family protein"
                     /protein_id="HCR9912906.1"
                     /translation="MNSTIWLALALVLVLEGLGPMLYPGAWKKMVSALAQLPENVLRR
                     FGGGLVVAGVVVYYMLRKTIG"
     gene            complement(5602..6606)
                     /gene="hflC"
                     /locus_tag="OPV72_000518"
     CDS             complement(5602..6606)
                     /gene="hflC"
                     /locus_tag="OPV72_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease modulator HflC"
                     /protein_id="HCR9912907.1"
                     /translation="MRKSVIAIIIIVLVVLYMSVFVVKEGERGITLRFGKVLRDDENK
                     PLVYAPGLHFKIPFIESVKMLDARIQTMDNQADRFVTKEKKDLIVDSYIKWRISDFSR
                     YYLATGGGDISQAEVLLKRKFSDRLRSEIGRLDVKDIVTDSRGRLTLEVRDALNSGSA
                     GTDDEVATPAADDAIAEAAERVTAETKGKVPVINPNSMAALGIEVVDVRIKQINLPTE
                     VSEAIYNRMRAEREAVARRHRSQGQEEAEKLRAAADYEVTKTLAEAERQGRIMRGEGD
                     AEAAKLFADAFSQDPDFYAFIRSLRAYEKSFEGNQDVMVLSPDSDFFRYMKTPSSTTR
                     "
     gene            complement(6609..7868)
                     /gene="hflK"
                     /locus_tag="OPV72_000519"
     CDS             complement(6609..7868)
                     /gene="hflK"
                     /locus_tag="OPV72_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsH protease activity modulator HflK"
                     /protein_id="HCR9912908.1"
                     /translation="MAWNQPGNNGQDRDPWGSSKPGSNSGGNGNKGGRDQGPPDLDDI
                     FRKLSKKLGGFGGGKGTGSGGGSSSQGPRPQLGGRIVAIAAAAVVIIWAASGFYTIKE
                     AERGVVTRFGKFSHLVEPGLNWKPTFIDDVTPVNVEAVRELAASGVMLTSDENVVRVE
                     MNVQYRVTDPQKYLFSVTSPDDSLRQATDSALRGVIGKYTMDRILTEGRTVIRSDTQR
                     ELEETIKPYNMGITLLDVNFQAARPPEEMKAAFDDAIAARENEQQYIREAEAYTNEVQ
                     PRANGQAQRILEEARAYKTQTILEAQGEVARFAKILPEYKAAPQITRERLYIETMEKV
                     LSHTRKVLVNDKSGNLMVLPLDQMLKGGNAPAAKSDNSASNLLRLPPSTKSNASGASN
                     TSSSNQGDIMDQRRANAQRNDYQRQGE"
     gene            complement(8083..9363)
                     /gene="hflX"
                     /locus_tag="OPV72_000520"
     CDS             complement(8083..9363)
                     /gene="hflX"
                     /locus_tag="OPV72_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HCR9912909.1"
                     /translation="MFDRYDAGEQAVLVHIYFSQDKDMEDLQEFESLVSSAGVEAMQV
                     ITGSRKAPHPKYFVGEGKAVEIAEAVKATGAAVVLFDHALSPAQERNLERLCECRVID
                     RTGLILDIFAQRARTHEGKLQVELAQLRHLATRLVRGWTHLERQKGGIGLRGPGETQL
                     ETDRRLLRNRIVQIQSRLEKVEKQREQGRQSRIKADVPTVSLVGYTNAGKSTLFNQIT
                     EARVYAADQLFATLDPTLRRIDVADVGETVLADTVGFIRHLPYDLVAAFKATLQETRQ
                     ATLLLHVVDAADVRVQENIEAVNTVLEEIDAHEIPTLMVMNKIDMLDDFEPRIDRDEE
                     NKPIRVWLSAQSGVGIPQLFQALTERLSGEVAQHTLRLLPQEGRLRSRFYQLQAIEKE
                     WMEEDGSVSLQVRMPIVDWRRLCKQEPALIEYVI"
     gene            complement(9435..9743)
                     /gene="hfq"
                     /locus_tag="OPV72_000521"
     CDS             complement(9435..9743)
                     /gene="hfq"
                     /locus_tag="OPV72_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone Hfq"
                     /protein_id="HCR9912910.1"
                     /translation="MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVI
                     LLKNTVSQMVYKHAISTVVPSRPVSHHSNNAGGGASNNYHHGSNAQGSTAQQDSEETE
                     "
     gene            complement(9826..10776)
                     /gene="miaA"
                     /locus_tag="OPV72_000522"
     CDS             complement(9826..10776)
                     /gene="miaA"
                     /locus_tag="OPV72_000522"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HCR9912911.1"
                     /translation="MNDVSKVSLPKAIFLMGPTASGKTALAIELRKVLPVELISVDSA
                     LIYRGMDIGTAKPNADELKAAPHRLLDIRDPSQAYSAADFRRDALAQMAEITAAGRIP
                     LLVGGTMLYFKALLEGLSPLPSADPEVRSRIEQQAAELGWEALHQQLQEIDPVAAARI
                     HPNDPQRLSRALEVFFISGKTLTELTQTSGDALPYQVHQFAIAPASRELLHQRIELRF
                     HQMLASGFEAEVRALFARGDLHTDLPSIRCVGYRQMWSYIEGEISYDEMVYRGVCSTR
                     QLAKRQMTWLRGWEGVRWLDSENPDRARKEVLQVVGAIAD"
     gene            complement(10769..12625)
                     /gene="mutL"
                     /locus_tag="OPV72_000523"
     CDS             complement(10769..12625)
                     /gene="mutL"
                     /locus_tag="OPV72_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HCR9912912.1"
                     /translation="MPIQVLPPQLANQIAAGEVVERPASVVKELVENSLDAGATRVDI
                     DIERGGAKLIRIRDNGCGIKKEELALALARHATSKIASLDDLEAIISLGFRGEALASI
                     SSVSRLTLTSRTAEQAEAWQAYAEGRDMDVTVKPAAHPVGTTLEVLDLFYNTPARRKF
                     MRTEKTEFNHIDEIIRRIALARFDVTLNLSHNGKLVRQYRAVAKDGQKERRLGAICGT
                     PFLEQALAIEWQHGDLTLRGWVADPNHTTTALTEIQYCYVNGRMMRDRLINHAIRQAC
                     EDKLGADQQPAFVLYLEIDPHQVDVNVHPAKHEVRFHQSRLVHDFIYQGVLSVLQQQT
                     ETTLPLEEIAPAPRHVPENRIAAGRNHFAVPAEPTAAREPATPRYSDGASGGNGGRQS
                     AGGWPHAQPGYQKQQGEVYRTLLQTPTTSPAPEPVAPALDGHSQSFGRVLTIVGGDCA
                     LLEHAGTIQLLSLPVAERWLRQAQLTPGQSPVCAQPLLIPLRLKVSADEKAALQKAQS
                     LLGELGIEFQSDAQHVTIRAVPLPLRQQNLQILIPELIGYLAQQTTFATVNIAQWIAR
                     NVQSEHPQWSMAQAISLLADVERLCPQLVKAPPGGLLQPVDLHSAMNALKHE"
     gene            complement(12635..13954)
                     /gene="amiB"
                     /locus_tag="OPV72_000524"
     CDS             complement(12635..13954)
                     /gene="amiB"
                     /locus_tag="OPV72_000524"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase AmiB"
                     /protein_id="HCR9912913.1"
                     /translation="MIYRIKNAVIAALILLCAQAGAASLSDIQVSNGEQQARITLSFI
                     GEPEYAYSQDGKRTVALDIRQTGVIQGLPLQFSGNNLVKTIRAGTPKDAQSLRLLVDL
                     TENGKTEAVKRQNGGNYTVIFTINADVPPPPPPVVAKRVESAPRPTEPARNPFKSSDD
                     RLTGVTSSNTVTRPAARASAGAGDKVVIAIDAGHGGQDPGAIGPGGTREKNVTIAIAR
                     KLRTLLNNDPMFKGVLTRDGDYFISVMGRSDVARKQNANFLVSIHADAAPNRDATGAS
                     VWVLSNRRANSEMANWLEQHEKQSELLGGAGDVLTNSQSDPYLSQAVLDLQFGHSQRV
                     GYDVATNVLSQLDGVGSLHKRRPEHASLGVLRSPDIPSILVETGFISNHGEERLLASD
                     RYQQQIADAIYRGLRKYFAAHPIQSAPQGSPGQTASTNQPGAITAAN"
     gene            complement(13971..14432)
                     /gene="tsaE"
                     /locus_tag="OPV72_000525"
     CDS             complement(13971..14432)
                     /gene="tsaE"
                     /locus_tag="OPV72_000525"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HCR9912914.1"
                     /translation="MMNRVIPLPDEQATLDLGQRVANACDGATVIYLYGDLGAGKTTF
                     SRGFLQALGHNGNVKSPTYTLVEPYALDNMMVYHFDLYRLADPEELEFMGIRDYFAND
                     AICLVEWPQQGKGVLPDPDVEIHIDYQAQGREARVSAVSSSGHSLLARLAD"
     gene            complement(14404..15951)
                     /gene="nnr"
                     /locus_tag="OPV72_000526"
     CDS             complement(14404..15951)
                     /gene="nnr"
                     /locus_tag="OPV72_000526"
                     /EC_number="4.2.1.136"
                     /EC_number="5.1.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional ADP-dependent NAD(P)H-hydrate
                     dehydratase/NAD(P)H-hydrate epimerase"
                     /protein_id="HCR9912915.1"
                     /translation="MMDHNMKKNPVSIPHSIWPADDIKRLERDAADAFGLTLYELMLR
                     AGDAAFRVARDSYPDARHWLVLCGHGNNGGDGYVVARLAQAAGISVTLLAQESDKPLP
                     EEAAQARDAWLNAGGIIHAADIIWPEATDLIIDALLGTGIAQEPRDPVAGLIEQANAH
                     PAPVVAVDIPSGLLAQTGTTPGAVISAAHTVTFIALKPGLLTGKARDVTGILHYDALG
                     LEGWLASQTPPLRRFDATQLGQWLTPRRPTSYKGDHGRLAIIGGDQGTAGAIRMAGEA
                     ALRTGAGLVRVLTRGENIASLLTARPELMVHELTPQSLEESLTWADVVVIGPGLGQQE
                     WGKKALQKVENVRKPMLWDADALNLLAINPDKRHNRVITPHPGEAARLLGCSVAEIES
                     DRLLSAQRLVKRYGGVVVLKGAGTIIAAEHHPLAIIDAGNAGMASGGMGDVLSGIIGA
                     LLGQKFTPYDAACVGCVAHGAAADLLAARYGARGMLATDLFTTLRRIVNPDVIDVNHD
                     ESSNSAT"
     gene            15950..17089
                     /gene="queG"
                     /locus_tag="OPV72_000527"
     CDS             15950..17089
                     /gene="queG"
                     /locus_tag="OPV72_000527"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HCR9912916.1"
                     /translation="MSKPLDLNQLAQNIKQWGLELGFQQVGITDTDLRASEPALQAWL
                     DKQYHGEMAWMARHGMMRARPHELLPGTLRVISVRMNYLPANAAFASTLKDPTLGYVS
                     RYALGRDYHKLLRSRLKKLGEQIQQYCGSLNFRPFVDSAPILERPLAEKAGLGWTGKH
                     SLILNREAGSFFFLGELLIDLPLPVDQPVEEGCGKCVACMTICPTGAIVEPYTVDARR
                     CISYLTIELEGAIPEAFRPLIGNRIYGCDDCQLICPWNRYSQLTDEADFSPRKALHNP
                     DLLELFSWSEAQFLKVTEGSAIRRIGHLRWLRNVAVALGNAPWSNAVITALESRKGEH
                     PLLDENIEWAIAQQIEKRNACIIEVQLPKKQRLVRVIEKGLVRDA"
     gene            complement(17359..17434)
                     /locus_tag="OPV72_000528"
     tRNA            complement(17359..17434)
                     /locus_tag="OPV72_000528"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(17399..17401),aa:Gly,seq:gcc)
     gene            complement(17591..17666)
                     /locus_tag="OPV72_000529"
     tRNA            complement(17591..17666)
                     /locus_tag="OPV72_000529"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(17631..17633),aa:Gly,seq:gcc)
     gene            17962..18681
                     /locus_tag="OPV72_000530"
     CDS             17962..18681
                     /locus_tag="OPV72_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter substrate-binding
                     protein"
                     /protein_id="HCR9912917.1"
                     /translation="MLLASLSVHAASVSARTLHFGTSATYAPYEFVDADNKIVGFDID
                     VANAVCKEMQAECSFTNQSFDSLIPGLRFKKFDAVIAGMDMTPKREQQVSFSQPYYEG
                     LSAVVVTRKGAYHTFADLKGKKVGLENGTTHQRYLQDKQQAITPVAYDSYLNAFTDLK
                     NNRLEGVFGDVAAIGKWLKNNPDYAIMDERASDPDYYGKGLGIAVRKGNDALLQEINA
                     ALDKVKASPEYAQMQEKWFTQ"
     gene            complement(18743..19288)
                     /gene="orn"
                     /locus_tag="OPV72_000531"
     CDS             complement(18743..19288)
                     /gene="orn"
                     /locus_tag="OPV72_000531"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020882950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoribonuclease"
                     /protein_id="HCR9912918.1"
                     /translation="MSADENNLIWIDLEMTGLDPERDRIIEIATLVTDASLNILAEGP
                     TIAVHQSDAQLALMDDWNVRTHTGSGLVDRVKASTMGERDAELATIEFLKTWVPAGKS
                     PICGNSIGQDRRFLFKYMPELEAYFHYRYLDVSTLKELARRWKPEILAGFTKQGTHQA
                     MDDIRESVAELAYYREHFIKL"
     gene            19395..20447
                     /gene="rsgA"
                     /locus_tag="OPV72_000532"
     CDS             19395..20447
                     /gene="rsgA"
                     /locus_tag="OPV72_000532"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313167.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small ribosomal subunit biogenesis GTPase RsgA"
                     /protein_id="HCR9912919.1"
                     /translation="MSKNKLSKGQQRRVNANHQRRLKTSAEKADYDDNLFGEPAEGIV
                     ISRFGMHADVESADGEVHRCNIRRTIRSLVTGDRVVWRPGKAAAEGVNVKGIVEAVHE
                     RTSVLTRPDFYDGVKPIAANIDQIVIVSAILPELSLNIIDRYLVGCETLQVEPLIVLN
                     KIDLLDDEGMDFVNEQMNIYRNIGYRVLMVSSHTQDGLKPLEEALTGRISIFAGQSGV
                     GKSSLLNALLGLQNEILTNDVSNVSGLGQHTTTAARLYHFPHGGDVIDSPGVREFGLW
                     HLEPEQITQGFVEFHDYLGHCKYRDCKHDADPGCAIREAVENGAIAETRFENYHRILE
                     SMAQVKTRKNFSDTDD"
     gene            20539..21507
                     /gene="psd"
                     /locus_tag="OPV72_000533"
     CDS             20539..21507
                     /gene="psd"
                     /locus_tag="OPV72_000533"
                     /EC_number="4.1.1.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463212.1"
                     /note="Phosphatidylserine decarboxylase is synthesized as
                     a single chain precursor. Generation of the pyruvoyl
                     active site from a Ser is coupled to cleavage of a Gly-Ser
                     bond between the larger (beta) and smaller (alpha chains).
                     It is an integral membrane protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylserine decarboxylase"
                     /protein_id="HCR9912920.1"
                     /translation="MLNSFKLSLQYILPKLWLTRLAGWGASKRAGWLTKLVIDLFVKY
                     YKVDMTEAQKPDTASYRTFNDFFVRPLRDDVRPLNTDPNILVMPADGVISQLGRIEED
                     KILQAKGHNYSLEALLAGNYLMADKFRNGTFVTTYLSPRDYHRVHMPCNGILREMIYV
                     PGDLFSVNYLTAQNVPNLFARNERVICLFDTEFGPMAQILVGATIVGSIETVWAGTIT
                     PPREGIIKRWTWPEGEHEGSVALLKGQEMGRFKLGSTVINLFAPGKVNLIASLASLSV
                     TKIGQPLATSTETFVAPEVEPAPLPAEEIKAEHDASPLVDNKKDDT"
     gene            21526..24852
                     /gene="mscM"
                     /locus_tag="OPV72_000534"
     CDS             21526..24852
                     /gene="mscM"
                     /locus_tag="OPV72_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="miniconductance mechanosensitive channel MscM"
                     /protein_id="HCR9912921.1"
                     /translation="MRLIIAFLMAWCLSTGAFAATAPDAKQITQELEQAKAAKPAQPE
                     AVEALQTALNALEERKGSLERAKQYQHVIDNFPKLSATLRAQLNNLRDEPRSVPPEMS
                     TEALNQEILQVSSQLLDKTREAQQEQERVREIADSLSQLPQQQNDARRQLNEIERRLG
                     AAGGSAALSQAQSLSMQAESAKLKALVDELELAQLSANNRQELARLRSELAEKQSQQL
                     DAYLQALRNQLNSLRQREAERALESTELLAENSAGLPEGIVEQFKVNRGLSQALNQQA
                     QRMDLVASQQRQATSQTLQVRQALNTLREQSQWLGVSNMLGEALRAQVARLPEMPKPQ
                     QLDTEMAQLRVHRMRYEELLNKQPQLRQIRQANGQPLTAEQNQILDAQLRTQRELLNS
                     LLQGGDTLILELTKLKVSNSQLEDALKEVNEATHRYLFWTADVSPLSLSWPVDLVQDL
                     RRLISLDTFNQLGKASIMMLTSKETLLPLFGALALVGFSLYSRQHFNRFLERSASRVG
                     KVTQDHFSLTLRTVFWSILVASPLPVLWATLGYGLQEAWPYPLAVAIGDGVTATVPLL
                     WVVMICAAFARPNGLFVAHFGWPRNRVAKAMRYYLMSIGLIVPLIMAVIMFDNLNDRE
                     FSGSLGRLCFILICGALALVTLSLKKAGIPLYLDKEGNGDNMVNSLLWNMLMGAPLIA
                     ILAAAVGYLATAQALLARLETSVAIWFLLLVIYHVIRRWMLIQRRRLAFDRAKHRRAE
                     MLAQRARGEEEPAHSSSLEGAVDIDESEIDLDAISAQSLRLVRSILMLIALLSVIVLW
                     SEIHSAFGFLENISLWDVTSTVQGVESLEPITLGAVLIAILVFIITTQLVRNLPALLE
                     LALLQHLDLTPGTGYAITTITKYLLMLIGGLVGFSMIGIEWSKLQWLVAALGVGLGFG
                     LQEIFANFISGLIILFEKPIRIGDTVTIRDLTGSVTKINTRATTISDWDRKEIIVPNK
                     AFITEQFINWSLSDSVTRVVLTIPAPADANSEEVTQILLTAAQRCSLVLDNPPPEIFL
                     VDLQQGIQIFELRIYAAEMGHRMPLRHEIHQLILAGFREHGIDMPFPPFQMRLESLGG
                     KQTGRTLTSAGKTSRPAGSL"
     gene            complement(24989..25309)
                     /locus_tag="OPV72_000535"
     CDS             complement(24989..25309)
                     /locus_tag="OPV72_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001682126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9912922.1"
                     /translation="MNDSSRDPIITEDEIRALNFTPEDILEIEKVILSSVHVARRKVA
                     MVVGMTIGTLRDRDEDKWKHVSDIYCAYVVRCLVFRGELVGYGDLFRMRYSEINLPVA
                     DLDA"
     gene            complement(25374..26876)
                     /gene="yjeM"
                     /locus_tag="OPV72_000536"
     CDS             complement(25374..26876)
                     /gene="yjeM"
                     /locus_tag="OPV72_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/gamma-aminobutyrate family transporter
                     YjeM"
                     /protein_id="HCR9912923.1"
                     /translation="MTHTIKKMSLIGLILMIFTSVFGFANSPSAFYLMGYSAIPWYIF
                     SALLFFIPFALMMAEMGSAYRKEEGGIYSWMNNSVGPRYAFIGTFMWFSSYVIWMVST
                     AAKIWVPFSTFVFGADMTQHWRIAGLEPTQVVGLLAVGWMILVTCVAARGINKIARIT
                     AVGGIAVMCLNLVLLLVSVAILLLNGGHFAQEINFTSSPNPGYHSGLAMLSFVVFAIF
                     AYGGIEAVGGLVDKTEKPEKNFAKGIVFAAIVISIGYSLAIFLWGVSTNWQQILSNSA
                     VNLGNITYILMSSLGTTLGNALNLSPEAAMTVGVWFARITGLSMFLAYTGAFFTLSYS
                     PLKAIIQGTPKALWPAPMTTLNANGMPATAMWLQCVLVSLFILLVSFGGDTASAFYNK
                     LTLMANVSMTLPYLFLALAFPFFKARQDLERPFVLFKTKASTLVATGVVVLVVTFANV
                     FTIIQPVIEAGDWDSALWMIGGPIFFSLLAMAIYQNYSSRMSADPEWAAE"
     gene            complement(27102..28079)
                     /gene="epmA"
                     /locus_tag="OPV72_000537"
     CDS             complement(27102..28079)
                     /gene="epmA"
                     /locus_tag="OPV72_000537"
                     /EC_number="6.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000004771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P--(R)-beta-lysine ligase"
                     /protein_id="HCR9912924.1"
                     /translation="MSETATWQPSASIPNLLKRAAIMAEIRRFFADRGVLEVETPCMS
                     QATVTDIHLFPFETRFVGPGHSQGINLYLMTSPEYHMKRLLAAGCGPVFQLCRSFRNE
                     EMGRHHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCQPAESLSYQQAFLRHLEID
                     PLSADKTQLREAAAKLDLSNIADTEEDRDTLLQLLFTMGVEPHIGKEKPTFIYHFPAS
                     QASLAQISTEDHRVAERFEVYYKGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQ
                     QPIDQNLLDALAAGLPDCSGVALGVDRLVMLALGAESLADVIAFTVDRA"
     gene            28402..30192
                     /gene="frdA"
                     /locus_tag="OPV72_000538"
     CDS             28402..30192
                     /gene="frdA"
                     /locus_tag="OPV72_000538"
                     /EC_number="1.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase (quinol) flavoprotein
                     subunit"
                     /protein_id="HCR9912925.1"
                     /translation="MQTFQADLAIIGAGGAGLRAAIAAAQANPNAKIALISKVYPMRS
                     HTVAAEGGSAAVAQDHDSFDYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLEQWGC
                     PWSRRPDGSVNVRRFGGMKIERTWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLD
                     ILVDDNHARGLVAMNMMEGTLVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMAL
                     SHGVPLRDMEFVQYHPTGLPGSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLG
                     EPKNKYMELGPRDKVSQAFWHEWRKGNTISTPRGDVVHLDLRHLGEKKLHERLPFICE
                     LAKAYVGVDPVKEPIPVRPTAHYTMGGIETDQNCESRVKGLFAVGECSSVGLHGANRL
                     GSNSLAELVVFGRLAGEQAMERAATAGAANSAALDAQVADIEQRLKNLVNQEGNENWS
                     KIRDEMGLSMEEGCGIYRTPELMQKTVDKLAELQERFKRVRISDTSSVFNTDLLYTIE
                     LGHGLNVAECMAHSALARKESRGAHQRLDEGCTERDDVNFLKHTLAFRDADGTTRLEY
                     SDVKITTLPPAKRVYGGEAEAADKKEKANG"
     gene            30185..30919
                     /gene="frdB"
                     /locus_tag="OPV72_000539"
     CDS             30185..30919
                     /gene="frdB"
                     /locus_tag="OPV72_000539"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020882957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase iron-sulfur protein"
                     /protein_id="HCR9912926.1"
                     /translation="MAEMKNLKVEVVRYNPETDTAPHSAFYEVPYDETTSLLDALGYI
                     KDNLSPDLSYRWSCRMAICGSCGMMVNNVPKLACKTFLRDYTNGMKVEALANFPIERD
                     LVIDMTHFIESLEAIKPYIIGNSRTPDQGPNVQTPAQMAKYHQFSGCINCGLCYAACP
                     QFGLNPEFIGPAAITLAHRYNEDSRDHGKKERMAQLNSPNGVWTCTFVGYCSEVCPKH
                     VDPAAAIQQGKVESSKDFLIATLKPR"
     gene            30930..31325
                     /gene="frdC"
                     /locus_tag="OPV72_000540"
     CDS             30930..31325
                     /gene="frdC"
                     /locus_tag="OPV72_000540"
                     /EC_number="1.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase subunit FrdC"
                     /protein_id="HCR9912927.1"
                     /translation="MTTKRKPYVRPMTSTWWKKLPFYRFYMLREGTAVPAVWFSIELI
                     FGLFALKHGAESWMGFVGFLQNPVVVILNLITLAAALLHTKTWFELAPKAANIIVKDE
                     KMGPEPIIKGLWVVTAVVTVVILYVALFW"
     gene            31336..31695
                     /gene="frdD"
                     /locus_tag="OPV72_000541"
     CDS             31336..31695
                     /gene="frdD"
                     /locus_tag="OPV72_000541"
                     /EC_number="1.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase subunit FrdD"
                     /protein_id="HCR9912928.1"
                     /translation="MINPNPKRSDEPVFWGLFGAGGMWGAIIAPVIVLLVGIMLPLGL
                     FPGDALSFERVLTFAQSFIGRVFLFLMIVLPLWCGLHRMHHAMHDLKIHVPAGKWVFY
                     GLAAILTVVTAIGVITL"
     gene            31807..32340
                     /locus_tag="OPV72_000542"
     CDS             31807..32340
                     /locus_tag="OPV72_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin family protein"
                     /protein_id="HCR9912929.1"
                     /translation="MRLLPVVAAVTAAFLVVACSSPTPPKGVTVVNNFDAKRYLGTWY
                     EIARLDHRFERGLEQVTATYSLRDDGGINVINKGYNPAREMWQKTEGKAYFTGSPNRA
                     ALKVSFFGPFYGGYNVIALDREYRHALVCGPNRDYLWILSRTPTLSEEIKQQMLAVAT
                     REGFDVNKLIWVKQSGS"
     gene            complement(32357..32674)
                     /gene="sugE"
                     /locus_tag="OPV72_000543"
     CDS             complement(32357..32674)
                     /gene="sugE"
                     /locus_tag="OPV72_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HCR9912930.1"
                     /translation="MSWIILLIAGLLEVVWAVGLKYTHGFSRLTPSIITITAMVISMA
                     LLSWAMKTLPVGTAYAIWTGIGAVGAAITGILLLGESASPARLLSLGLIVAGIIGLKL
                     SAH"
     gene            32930..33517
                     /locus_tag="OPV72_000544"
     CDS             32930..33517
                     /locus_tag="OPV72_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCR9912931.1"
                     /translation="MLKILVIDRCHFTRTGMEAWLNHTDVLSSSLLVSGMNNLILAKE
                     HILQWKPHLVIADLYGFLNDALPEQPINAFFAACRMTPLVLLQSGNMPYRSQYASHAV
                     LSKHTPLHELAQRIKGALYTHPLQEAPESATPLLSPQEEKVLAMWTEGTSNKEIAYAL
                     GIHGKTVYTYKRNIRMKLHMDNRYSPFLMLPEKID"
     gene            complement(33548..33694)
                     /gene="ecnB"
                     /locus_tag="OPV72_000545"
     CDS             complement(33548..33694)
                     /gene="ecnB"
                     /locus_tag="OPV72_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein toxin entericidin B"
                     /protein_id="HCR9912932.1"
                     /translation="MVKKTIAAIFSVLVLSTVLTACNTTRGVGEDISDGGSAISGAAT
                     RAQQ"
     gene            complement(33802..33936)
                     /locus_tag="OPV72_000546"
     CDS             complement(33802..33936)
                     /locus_tag="OPV72_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463199.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="entericidin A/B family lipoprotein"
                     /protein_id="HCR9912933.1"
                     /translation="MMKRFIGLVALVLLTGTLLTACNTARGFGEDIQHLGHAISRAAS
                     "
     gene            complement(33997..34563)
                     /gene="efp"
                     /locus_tag="OPV72_000547"
     CDS             complement(33997..34563)
                     /gene="efp"
                     /locus_tag="OPV72_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004871142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HCR9912934.1"
                     /translation="MATYYSNDFRSGLKIMLDGEPYAVESSEFVKPGKGQAFARVKLR
                     RLLTGTRVEKTFKSTDSAEGADVVDMNLTYLYNDGEFWHFMNNETFEQLSADAKAIGD
                     NAKWLLDQAECIVTLWNGQPISVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGA
                     VVKVPLFVQIGEVIKVDTRSGEYVSRVK"
     gene            34604..35632
                     /gene="epmB"
                     /locus_tag="OPV72_000548"
     CDS             34604..35632
                     /gene="epmB"
                     /locus_tag="OPV72_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF-P beta-lysylation protein EpmB"
                     /protein_id="HCR9912935.1"
                     /translation="MAHIVTLNTPLREDWLAQLADVVTNPDELLHLLQIEADENLRAR
                     QDARRLFALRVPRAFIARMEKGNPDDPLLRQVLTSRDEFIVAPGFSTDPLEEQHSVVP
                     GLLHKYQNRALLLVKGGCAVNCRYCFRRHFPYAENQGNKRNWTVALEYIAAHPELDEI
                     IFSGGDPLMAKDHELDWLLTQLEAIKHVKRLRIHSRLPIVIPARITDELVARFDQSCL
                     QILLVNHINHANEVDEAFCLAMKKLRHVGVTLLNQSVLLRGVNDNAQTLANLSNALFD
                     AGVMPYYLHVLDKVQGAAHFMVTDDEARQIMRELLTLVSGYMVPRLAREIGGEPSKTP
                     LDLQLRQC"
     gene            35914..36771
                     /locus_tag="OPV72_000549"
     CDS             35914..36771
                     /locus_tag="OPV72_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjeJ family protein"
                     /protein_id="HCR9912936.1"
                     /translation="MALTIKGLNTGVIRHNDKFIALALKVKSLRNKETLLFFPVLALR
                     DLLIGLEHRLYLQYSLPEQEQEKRQKAKSSHVLKMHENIPAILREELENADVNQRVES
                     LALSDNTEKVLTFTLKLHNGSHLDLQVGEWQVEVLVMAIIHAINNAEMRELALRISSM
                     LDFLPLYDADCLDNGNIEFDTYNQPDWKHNLYNHYLALVYRYTDEAGQSHDCGTIIKT
                     RSQSGSKEAEAISRRLLNFSPRLKKLEGKPCKVFVRTLGTGKAARLTQDQCMRALHNL
                     RMASSQEKR"
     gene            complement(36819..37172)
                     /locus_tag="OPV72_000550"
     CDS             complement(36819..37172)
                     /locus_tag="OPV72_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463195.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4156 domain-containing protein"
                     /protein_id="HCR9912937.1"
                     /translation="MHVKYLAGIVGAALLMAGCSSSNELTAAGQNVRFVEDKPGAECQ
                     LIGTATGKQSNWFSGQHGEEGGSMRGAANDLRNQAAAMGGNVLYGVSSPSQGMLSSFV
                     PTASEMNGQVYKCPN"
     gene            complement(37416..39062)
                     /gene="groL"
                     /locus_tag="OPV72_000551"
     CDS             complement(37416..39062)
                     /gene="groL"
                     /locus_tag="OPV72_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120975.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HCR9912938.1"
                     /translation="MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSF
                     GAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQSIITE
                     GLKAVAAGMNPMDLKRGIDKAVAAAVEELKALSVPCSDSKAIAQVGTISANSDETVGK
                     LIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDRGYLSPYFINKPETGAVELESP
                     FILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAV
                     KAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIID
                     GVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEK
                     KARVEDALHATRAAVEEGVVAGGGVALIRVASKIADLKGQNEDQNVGIKVALRAMEAP
                     LRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAA
                     SVAGLMITTECMVTDLPKSDAPDLGAAGGMGGMGGMGGMM"
     gene            complement(39106..39399)
                     /locus_tag="OPV72_000552"
     CDS             complement(39106..39399)
                     /locus_tag="OPV72_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000027827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HCR9912939.1"
                     /translation="MSIRPLHDRVIVKRKEVESKSAGGIVLTGSAAGKSTRGEIIAVG
                     KGRILDNGTVQPLDVKVGDIVIFNDGYGVKSEKIDNEEVLIMSESDILAIVEA"
     gene            39675..40916
                     /locus_tag="OPV72_000553"
     CDS             39675..40916
                     /locus_tag="OPV72_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCR9912940.1"
                     /translation="MNELKKELGLVQGVILLTTSLLGTGVFALPELAALAAGDISLWA
                     WPLLIILIFPIAIVFAVLGRHFPHAGGVAHFVGMAFGPRLQRVISWLFLSVIPVSFPA
                     ALHIAVGFGQALFGWQSEQLLFGELGTLGLLWFMGSRGASSSANLQAIIAGLIIALIA
                     AILWKGAIKPADITFPAANEIIFSRLCTALAIMFWGFVGIEAFTHLSSEFKNPERDFP
                     RALIIGLMLAGAIYWTCTAVVLHFGVYSDKIAATASLPLIIVHLFGIQALWIACIIGY
                     LTCFASLNMYAQSFARLIWTQMQYQPDHYLAQLSPGRLPLHALNVILACCCVSSLVVY
                     ALKINLNALIVYANGIFIMLYLLCMLAGCRLLKGRCYALAVTGCLLCLLLLVMLGWKS
                     LYAIIMLAALWLFLPKRKRMA"
     gene            complement(40975..41451)
                     /gene="fxsA"
                     /locus_tag="OPV72_000554"
     CDS             complement(40975..41451)
                     /gene="fxsA"
                     /locus_tag="OPV72_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein FxsA"
                     /protein_id="HCR9912941.1"
                     /translation="MRWIPFLAVFLYVYIEISIFIQVAHVLGVLMTLILVIFTSVIGM
                     SLVRNQGFKNFLLMQQKMAAGESPAAEMIKSVSLIIAGLLLLLPGFFTDFLGLLLLLP
                     PVQKHLTLKLLPHLRFSRMPGGGFSAGTGGGETFDGEYQRKDDDRDRIEHKDDRRD"
     gene            41792..43228
                     /gene="aspA"
                     /locus_tag="OPV72_000555"
     CDS             41792..43228
                     /gene="aspA"
                     /locus_tag="OPV72_000555"
                     /EC_number="4.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate ammonia-lyase"
                     /protein_id="HCR9912942.1"
                     /translation="MSNNIRIEEDLLGTREVPAEAYYGVHTLRAIENFYISNNKISDI
                     PEFVRGMVMVKKAAALANKELQTIPKSVANAIIAACDEVLNNGKCMDQFPVDVYQGGA
                     GTSVNMNTNEVLANIGLELMGHQKGEYQYLNPNDHVNKCQSTNDAYPTGFRVAVYASI
                     VKLIDAINQLREGFERKAVEFQDILKMGRTQLQDAVPMTLGQEFRAFSILLKEEVKSI
                     ERTAELLLEVNLGATAIGTGLNTPKEYSPLAVKKLAEVTGFACVPAEDLIEATSDCGA
                     YVMVHSALKRLAVKMSKICNDLRLLSSGPRAGLNEINLPELQAGSSIMPAKVNPVVPE
                     VVNQVCFKVIGNDTTVTMAAEAGQLQLNVMEPVIGQAMFESIHILSNACYNLLEKCVN
                     GITANKEVCEGYVYNSIGIVTYLNPFIGHHNGDIVGKICAETGKSVREVVLERGLLTE
                     AELDDIFSVQNLMHPAYKAKRYTDESEQ"
     gene            43343..44644
                     /gene="dcuA"
                     /locus_tag="OPV72_000556"
     CDS             43343..44644
                     /gene="dcuA"
                     /locus_tag="OPV72_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic C4-dicarboxylate transporter DcuA"
                     /protein_id="HCR9912943.1"
                     /translation="MIVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAAIGVKPGT
                     IPFDVISIIMAVIAAISAMQVAGGLDYLVNQTEKLLRKNPKYITILAPIVTYFLTIFA
                     GTGNISLATLPVIAEVAKEQGIKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGH
                     GISYIHLLSVVIPSTLLAVLVMSFLVTMLFNSKLSDDPIYRKRLEEGLIELRGEKQIE
                     IKPMAKNSVWLFLLGVICVVVYAIVNSPSLGLVEKPLMNTTNAILIIMLSVATLTTIL
                     CKVETDAILNSSTFKAGMSACICILGVAWLGDTFVSANIDWIKDTAGSVIQGHPWLLA
                     VIFFFASALLYSQAATAKALMPMALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQ
                     MDDTGTTRIGKFVFNHPFFIPGTLGVVLAICSGFLLGSFML"
     gene            44765..45112
                     /gene="cutA"
                     /locus_tag="OPV72_000557"
     CDS             44765..45112
                     /gene="cutA"
                     /locus_tag="OPV72_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent cation tolerance protein CutA"
                     /protein_id="HCR9912944.1"
                     /translation="MLDVKSQDISIPEAVVVLCTAPDEATAQDLAAKVLAEKLAACAT
                     LLPGATSLYYWEGKLEQEYEVQMILKTTVSHQQALIDCLKSHHPYQTPELLVLPVTHG
                     DTDYLSWLNASLR"
     gene            45088..46791
                     /locus_tag="OPV72_000558"
     CDS             45088..46791
                     /locus_tag="OPV72_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-disulfide reductase DsbD"
                     /protein_id="HCR9912945.1"
                     /translation="MAQRIFTLILLLCSTSAFAGLFDAPGRSQFVPADRAFVFDFQQN
                     QHDLTLSWQVKEGYYLYRKQISITPTKADIAAVQLPAGVWHEDEFYGKSEIYRKRLNV
                     PVTVNQAAAGATLTITYQGCADAGFCYPPETKTVPLSEVAAAIDATPTPAVTQTGETS
                     KPAAQLPFSALWALLIGIGIAFTPCVLPMYPLISGIVLGGRQRLSTGRALLLAFIYVQ
                     GMALTYTALGLVVAAAGLQFQAALQHPYVLIGLAIVFTLLALSMFGLFTLQLPSSLQT
                     RLTLMSNRQQGGSPGGVFVMGAIAGLICSPCTTAPLSAILLYIAQSGNMWLGGGTLYL
                     YALGMGLPLMLVTVFGNRLLPKSGPWMAHVKTAFGFVILALPVFLLERIIGEAWGLRL
                     WSLLGVAFFGWAFITSLQARRAWMRIVQIILLAAALISVRPLQDWAFGSPSAQAPAHL
                     NFTAISTVDELNQALAQAKGKPVMLDFYADWCVACKEFEKYTFSDPRVQQVLGDTVLL
                     QANVTANNAQDVALLKHLQVLGLPTILFFDAQGQEQPQARVTGFMDAATFSAHLHDRQ
                     P"
     gene            46828..47403
                     /locus_tag="OPV72_000559"
     CDS             46828..47403
                     /locus_tag="OPV72_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCR9912946.1"
                     /translation="MQREDILGEALKLLETQGIADTTLEMVAERVNRPLDTLQRFWPD
                     KEAILYDALRYLSQQVDIWRRQLLLDETFSAEQKLLARYSALSECVSNNRYPGCLFIA
                     ACTFYPDPTHPIHQLANQQKRAAHDFTHGLLTTLEIDDPAMVARQMELVLEGCLSRML
                     VNRSQADVDTAQRLAEDILRFAQCRQGGALT"
     gene            47519..47594
                     /locus_tag="OPV72_000560"
     tRNA            47519..47594
                     /locus_tag="OPV72_000560"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:47552..47554,aa:Phe,seq:gaa)
     gene            47754..49013
                     /locus_tag="OPV72_000561"
     CDS             47754..49013
                     /locus_tag="OPV72_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000954536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase arm-type DNA-binding domain-containing
                     protein"
                     /protein_id="HCR9912947.1"
                     /translation="MLTDSKIRAAKPLAKSYKLTDAQGLYLTVSTSGSKLWYFRYRFE
                     GKENRLAFGPYPQVTLAEAREKRDAARKLLVSGVCPSLPRKAEKAAVDGTRTFQYIAT
                     AWHSSCLKLWSEDHADKILTCLKRYVFPDIGAMDIAEVETRHLAQLVKSIDDKGVHDV
                     AGRVRQHLTKIMRHAVQQGTIKYNPAYDLDGVVTPVVTQHHPALPLKRLPELLDKING
                     YKGRELTRLALELNLHVFLRSSELRLARWDEFNLKARIWTVPAKREAVKNVRFSERGA
                     KMKDEHLVPLSAQAVALLEQIKEITGESVFVFAGAHSMNKPMSENTINKALRVIGYDT
                     KTEVCGHGFRTMACSALNESALWSKDAIERQMSHKERNGVRAAYVHKAEHLEARMEMM
                     QWWSDYLDMSREGYVAPYIYARRHKAA"
BASE COUNT        11406 a        13509 c        12546 g        11613 t
ORIGIN      
        1 gcttcaaaca gacaaatccc ggtcgccaca gagacattca gcgatgacac gctaccggcc
       61 ataggaatgc tgatcagctc atcgcagtgc tcacgggtca gacgacgcat accttcacct
      121 tctgcgccca tgaccagcgc catgcggcca ggcattttgc tctgatacag cgtatggtca
      181 gcctcgcccg ccgttccgac aatccagata ttctcttcct gcaacatgcg catcgtgcgc
      241 gccaggttgg tgacgcggat caacggcacg ctttccgctg cgccgcaggc gactttcttc
      301 gccgtcgcgt taagttgcgc ggagcggtct ttcggcacga ttaccgcatg tacgcctgca
      361 gcatcggcgc tgcgcagaca ggcgccaaga ttatgcggat cggtgacgcc atcgaggatc
      421 aacaaaaagg ggcgatcgtg taatgcgatc agatccggta gatcgttttc ctgatactgc
      481 cggcctggtt tcacacgagc gataatgccc tgatgcacgg caccgtcgct tttctcgtcg
      541 agatattggc ggtttgccag ctggataacc acgccctggg actcaagggc gtgaatcagc
      601 ggcaacagac gtttatcttc acggcctttt aaaataaagg cttcctgaaa acgttcaggg
      661 gcgcgctcca gcagggcctg cactgcgtgg atgccgtaaa tcatttcgct cattaatgta
      721 ctcgttgttt acgttttgcc gggggcgcta cgcttgcccg gcctacagat aattgaccct
      781 cttctgtttg aagagggtat tgctcactct gccgcttttt tcttcgccgc acgcttcgct
      841 ttggtcgctg cggctatttt ctgcgtttta gccgatggct tttttgcttt tctcgcgtct
      901 ttcttcgctg ctttcggctt cgcttttttc tcgccgcgga aggcgctatc aggctcgaag
      961 ttaacctttt tacctacctg acgacgttta ccggcgtttt tactttcacc ttttttcgct
     1021 ttttcacgcg ccgttttgcc gacgttacgc ggtgcgcgct cgctggaaat caagctaaag
     1081 tcaattttcc gttcgtccat attcaccgct tcgacgcgta cctcgacccg gtcgcccagg
     1141 cgatatgtct gcccgccgga ttcgccaatc agacgttgcc ctacctgatc gaagcgatag
     1201 taatcgttat ccagtgagga aacgtgtacc agcccatcga taaacagttc atcaagacgg
     1261 acaaagaagc cgaaaccggt gacgctggca atcacgccct taaagacgtt gcctacctga
     1321 tccagcataa agtcacattt cagccagtcg gagacatcac gcgtcgcttc atcagcgcgg
     1381 cgttccgcca tcgaacagtg ctggccgagc tgcaacatct cttccatcga gtagtgataa
     1441 ccgcccgttt ctgtggtgtt gcccttgttc ccttgctctt tagccagcag gtacttaatg
     1501 gcgcggtgca aagaaagatc cggatagcgg cgaatcggcg aggtaaagtg cgcataagac
     1561 tgcaacgcca ggccaaagtg cccgcggttt tccggatcgt aaatcgcctg cttcattgaa
     1621 cgcagcagca tagtttgcag catttcggcg tccggcctgt cggcaatcga ttcaagcagt
     1681 tcggcataat cgcgcggttc cggtttattt ccgcccggca gctccaaccc cagctccgcc
     1741 agtacggagc ggaatgaggt gatcgcttcg gtggtgggct tatcatgaat acggaataac
     1801 gccggctctt tagctttttc gacaaagcgc gccgccgaga tattcgccat gatcatgcac
     1861 tcttcgataa gcttatgcgc gtcattacgc tgggtctgtt cgatacgctc aatgcgacgc
     1921 tcggcgttaa agataaactt cgcctcttcg ctctcaaacg agatcccccc gcgttcttca
     1981 cgcgctttat ccagcacttt gtagaggttg tgcagctctt caatatgctt caccagcggc
     2041 gcatattgtt cacgcagatc ctgatcgccc tgcagcatat gccagacttt ggtataggtc
     2101 agacgcgcat gggagctcat caccgcttca tagaatttgt agccggtcag ccgacctttc
     2161 gccgagatgg tcatttcaca gaccatacac agcctgtcaa cctgcgggtt tagcgaacac
     2221 aggccgttgg agagcacctc cggcaacatt gggacaacct gtgacgggaa gtaaaccgac
     2281 gtgccgcgat tgcgcgcctc gcgatccaac ggcgttggcg gccgtacata atagctcacg
     2341 tcagcaatag cgacccacaa acgccagccg ccgccgcgtt ttttctcaca gtaaaccgcg
     2401 tcgtcaaagt cacgggcatc ttcgccatca atcgtgacca gcggcaaatc gcgcagatcg
     2461 acacgaccga ctttcgcctc ttccggcacc tcttctttca gcccggcgac ctgctgctct
     2521 accgcctgcg gccagatgta gggtatttca tgggtacgca gcgccatatc aaccgccata
     2581 ccggtaccca tattgtcgcc cagcacttcg acgattttcc ctaccgcttt agtacggcga
     2641 gttggacgtt gggtcagttc aaccacgacc acgaacccca tccgcgcgcc catgacgtct
     2701 tctggcggga taagaatgtc gaagctgaga cggctgtcgt ccggcaccac aaagccgacg
     2761 cccgcatcgg tgaaataacg cccgactatc tgactggttt tcggtaccag tacacggacg
     2821 atacgcgctt cgcggcgacc tttacgatcg gcgcccagcg gctgcgccag cacctgatcg
     2881 ccatgaatac aggttttcat ctgctcgctg gaaagataca gatcgtcttt gcggccttcg
     2941 acacgtaaga aaccgtaacc atcacgatga ccgatcacgg tgcctttcag caggtcgagg
     3001 cgttccggca gcgcatagca ctggcggcgg gtaaagacca gttgtccatc gcgctccatc
     3061 gcgcgcaggc ggcgacgcaa ggcttcaagc tgctcttcgc cttcaatatt cagttctacg
     3121 gccagttctt cgcgactggc cggtttttca cgtttcgtta aatgttcgag gataaattcc
     3181 cggctcggga taggattcgc gtatttttct gcttcgcgtt cctggaaagg atcttgtgac
     3241 attgaggttc ctccattgtc atctctaatg aagtttactt cactccacca gtaataattt
     3301 ataaagcggt tgattctctt caaccaaatc ggcaagcgtg tagttatcca gctccttgag
     3361 aaaactctgc acggccttag aaagcgcctg tttcagacga caggcagggg tgatgtggca
     3421 aaattcgctg ctacagttga ccagtgataa gggttccagc tcacgcacca catcgccaat
     3481 acaaatagta ttagccggtt tacccaggcg gataccgcca ttttttcccc gaacggcggt
     3541 gacaaagccc gcccggctaa gctgattgat aattttgacc atatgattac gggacacgtc
     3601 gtagacttct gtcacctcag aaatgctggt cattcgtcca tctggtaacg acgccatata
     3661 gattagcgca cgtaagccgt aatcggtgaa actcgttaac tgcacatcaa cctcaggaaa
     3721 agggaaaacg ggatataact tatctgtatt gatgataaac cagccacctg tcaggctgct
     3781 aatttatttc ggttcaggaa ggaaaaaagc ggggaacaat gacgcatttg agccgaagga
     3841 tgatgcaaag catcttatcc ggccaacaaa tgcgtactca tcatagaccc ggtaagcgta
     3901 gcgttaccgg gcatcatcca tcaattacgc gtcgaacgga tcgcgcagaa tcatcgtctc
     3961 agtacgatcg gggccggtag aaataatatc aatcggcacg ccggtcagtt cttcgatacg
     4021 tttgatgtag ttcagcgccg cctgcggcag gccgctacga tctttcacgc cgaaggtgga
     4081 ttcagaccag cccggcatgg tttcgtaaat cggctctaca cctttccagt cgtcagctgc
     4141 cagcggagtg gtagtcactt cgcgaccatc cggcatacgg taagccacgc agagtttcac
     4201 ctctttcagg ccatccagca cgtccagttt ggtcaggcag aagccagaca gggagttcag
     4261 ctgtaccgca cgacgaacgg caacggtgtc cagccagccg gtacgacgac gacggccggt
     4321 agtggcgccg tattcgttac cctgcttgca gaggaactcg ccggtttcat caaacagttc
     4381 ggtcgggaac ggacctgcac ctacacgagt ggagtaagct ttgaggatac ccagaacgta
     4441 atcaacataa cgcgggccca ggccggaacc ggtcgccacg ccacccgcag tggtgttaga
     4501 agaagttacg tacggataag taccgtggtc gatatccagc agggtaccct gcgcaccttc
     4561 aaacatgacg aaatcgccac gctgacgcgc ctggtcgagc aggtctgaaa cgtcaacaac
     4621 catagaagtc aggatgtcgg caacagccat cgtatcatcc agaactttct ggtaatcaac
     4681 cgcttcagct ttgtagtagt taaccaactg gaagttgtga tattccatca cttctttcag
     4741 tttttcagca aaggtttctt tgtcgaaaag gtcaccaaca cgcagaccgc gacgtgccac
     4801 tttatcttca taagcaggcc cgattccacg accggtggtg ccgatcgctt tcgcgccacg
     4861 cgctttctca cgcgcgttat ccagcgcaac gtgataatca aggatcagcg gacaggcttc
     4921 agacagcagc agacgctcac gaacggggat gccacggtct tccagttctt tcatctcttt
     4981 catcagcgcg ctcggagaca gcacaacacc gttaccgatg atgctggtta cattctcgcg
     5041 aagaatacct gatggaataa gatggagaac ggttttttca ccgttgatta cgagagtatg
     5101 gcctgcgttg tgaccgccct ggtagcgtac aacatattta gcccgttcag tcagaagatc
     5161 gacgatcttt cctttacctt cgtcacccca ttgggtgccc agtacgacga cgttgttacc
     5221 catttttcaa aatcaccgtt tgcttaaaaa tggattctac catcgctttt tcagatatac
     5281 agcacttttt gcactcaatc tgcggcaaat ccgaccactt tttgctcagc caatcgtttt
     5341 cctcaacatg tagtagacca caactcccgc gaccacaagt ccgccgccaa aacgacgtaa
     5401 aacattttcc ggcagttgcg ccagtgccga aaccattttt ttccatgcgc cgggatacag
     5461 catcggtccc agcccttcga ggactaatac cagagcaagc gccaaccaga ttgttgaatt
     5521 catttatcgc ccttataaaa gaaaaccacc ggcatccttt ggatgcggtg gttttgctgg
     5581 tctaaaaccg ctgacgctat tttagcgtgt cgtcgaactc ggtgtcttca tgtagcggaa
     5641 gaaatcgctg tccgggctca gtaccatcac gtcctgatta ccttcgaagc tcttctcgta
     5701 agcgcgcaga ctacgaatga acgcgtagaa atcagggtcc tggctgaacg cgtcggcaaa
     5761 cagcttcgcg gcttcagcat caccttcacc acgcatgata cgcccctgac gctcggcttc
     5821 cgccagagtt ttcgtcacct catagtcagc agccgcacgc agtttttccg cttcttcctg
     5881 accttgtgag cgatgacgac gcgcgaccgc ttcacgctcg gcgcgcatac ggttgtaaat
     5941 cgcctcagaa acctcggtcg gcaggttgat ctgcttaata cgcacatcga ccacttcgat
     6001 acccaacgcc gccatactgt tcgggttgat gaccggtact ttacctttgg tttccgccgt
     6061 gacgcgttcc gccgcttcgg caatcgcgtc atccgccgcc ggggtcgcca cttcatcatc
     6121 agtgccggct gaaccggagt tcagcgcgtc gcgcacttcc agagtcagac gaccacgaga
     6181 atcggtcacg atgtctttta cgtccaggcg accaatctca gaacgcaaac ggtccgagaa
     6241 cttacgtttt aacagcactt cggcttgcga aatatcgccg ccgccggtcg ccagatagta
     6301 acggctaaag tcgctgatac gccatttgat gtaggagtcg acaatcaggt ctttcttctc
     6361 tttagtcaca aagcgatcgg cctggttatc catcgtctgg atacgcgcat caagcatttt
     6421 cactgattca ataaacggga tcttaaagtg cagacccggc gcgtaaacca gcggtttgtt
     6481 ctcatcgtca cgcagaactt taccaaaacg cagcgtaatg ccgcgctcgc cctctttgac
     6541 cacaaagacg gacatgtaga gcactaccag cacgatgatg ataatcgcaa taactgactt
     6601 acgcatcgtt attccccctg acgctggtag tcgttacgct gcgcattcgc gcggcgttgg
     6661 tccataatat cgccctgatt tgaggacgac gtgttgcttg ctccgctggc gttagacttt
     6721 gtggacggcg gcaggcgcag caggttgctg gcgctattgt cgctctttgc cgccggcgca
     6781 ttcccgcctt tcagcatctg atctaacggc agcaccatta aattaccgct cttgtcgtta
     6841 accagtactt tacgggtatg gctcagcact ttttccatcg tttcaatata cagacgctcg
     6901 cgcgtaatct gcggcgcggc tttatattct ggcaaaatct tcgcaaaccg ggcgacttca
     6961 ccctgcgctt ccaggatagt ctgggtttta taggcacgtg cctcttccag aatacgctgc
     7021 gcctgaccgt tggcgcgcgg ctgaacttcg ttggtatacg cttccgcttc acgaatgtac
     7081 tgctgctcgt tttcacgtgc ggcaatcgcg tcgtcaaagg cggctttcat ctcttccggc
     7141 ggacgcgcag cctggaagtt cacgtccagc agggtaatcc ccatgttgta cggtttgata
     7201 gtctcttcca gctcgcgttg ggtatcgcta cgaataacgg tacgaccttc ggtcagaatg
     7261 cgatccatcg tgtatttacc aatgacgcca cgcaacgcgc tgtcggtggc ctgacgcagg
     7321 ctatcgtccg ggctggtcac gctaaacaga tatttctgcg gatcggtgac gcggtattgc
     7381 acgttcattt caacgcgcac gacgttttca tcagacgtca gcatcacgcc tgacgccgcc
     7441 agttcgcgca ccgcttcgac gttcaccggc gtgacgtcgt caataaatgt cggcttccag
     7501 ttcagacctg gctctaccag atggctgaat ttaccaaaac gcgtcacaac gccgcgctcg
     7561 gcttctttaa tggtataaaa accgctggcc gcccagataa tgactactgc cgccgcggcg
     7621 atggcgacaa tacggcctcc cagttgcgga cgcgggcctt gcgatgagct accgccgccg
     7681 gaaccggtgc ctttaccgcc cccaaaacca ccgagttttt tactcagctt acggaagata
     7741 tcatccagat cgggaggtcc ctgatcgcgg ccacctttgt ttccatttcc cccagagttg
     7801 ctgccaggtt tgctgcttcc ccacgggtcg cggtcctgtc cgttattacc gggctgattc
     7861 cacgccatgt ttgtgctcca tatttgttat gcggtgatcc ccgttgtctt tcgacctcag
     7921 aggataaggc gaaattactc catgcttcag acgaaccgcc gttacagaca tcatctttca
     7981 ggctacgcct tgagtggcgg cttttttacc ccaggtcact tcgttgtgag ctcctgaaat
     8041 tctctcagct accgcttcaa tacgacctga atgacttcgc gtctagatca cgtattcgat
     8101 caacgctggt tcttgtttac agaggcgacg ccagtcgaca atcggcattc gtacctgcag
     8161 actgacgcta ccgtcttcct ccatccactc tttttctatt gcctgaagct gataaaaccg
     8221 gcttctcaga cgcccttcct gcggcagcaa acgcagcgta tgctgcgcca cctcgccgga
     8281 aagacgctcc gtcaaagcct gaaaaagctg tggtattccc acgccgcttt gcgctgaaag
     8341 ccaaacgcgg atgggtttat tctcttcatc tctgtcgata cgcggttcaa agtcgtccag
     8401 catatcgatt ttgttcatca ccattaaggt ggggatttcg tgagcgtcaa tctcttcaag
     8461 aacggtgttt accgcctcga tgttttcctg cacacgaaca tccgccgcat cgaccacatg
     8521 cagcagcagc gtcgcctgac gcgtctcctg cagggtagct ttaaaggcag ccaccagatc
     8581 gtacggtaaa tggcggataa agcctaccgt atccgccaga acggtttcac cgacatccgc
     8641 tacatcaata cgacgtaacg tggggtccag cgtcgcaaat agctgatctg ccgcatagac
     8701 ccgcgcttca gtgatctgat taaaaagggt ggattttccg gcgttggtat agcccaccag
     8761 cgataccgtc ggaacgtcgg ccttgatgcg cgactgccgc ccctgctcac gttgcttctc
     8821 aactttctcc aggcgcgact gaatctgcac aatgcgatta cgcagtaaac gacggtcggt
     8881 ttcgagctgg gtttcacccg gaccgcgcaa accaatcccg cctttctgac gttcaaggtg
     8941 ggtccagcca cgcaccagac gcgtagccag atggcgtagc tgcgccagct caacctgcaa
     9001 cttaccttca tgggtacgcg cacgttgggc aaaaatatct aagataagac cggtgcgatc
     9061 gataacccgg cactcgcaca aacgctccag gtttcgctcc tgggctggac tcaatgcatg
     9121 atcaaacaat acgaccgctg cgccagtcgc tttcacggct tccgcaattt caactgcctt
     9181 accttcacct acaaagtact tcgggtgcgg tgctttacgg ctaccggtaa tcacctgcat
     9241 tgcttcgaca ccggcggaag agaccagaga ttcaaactcc tggaggtctt ccatatcttt
     9301 gtcttgcgaa aaatagatgt gtaccagtac cgcctgctca ccggcatcat aacggtcaaa
     9361 caagcgtaaa ccctcttaat aaccagcggg ggcgattatc cgacgccccc gacatggata
     9421 aacagcgcgt gaacttattc agtctcttcg ctgtcctgtt gcgcagtaga accctgcgcg
     9481 ttgctaccgt gatggtagtt attgctggcg ccgccaccgg cattgttgct gtgatgggaa
     9541 accgggcgag acgggacaac agtagaaatc gcgtgcttat aaaccatctg gctgaccgtg
     9601 tttttcaaca ggatcacgaa ctgatcaaag gactcgattt gaccttgcag cttaatacca
     9661 ttcaccaaat aaatagaaac tggaacacgt tcccgacgca atgcgttcag gaacggatct
     9721 tgtaaagatt gccccttagc cattctcttt tccttatatg cttatttgta ctttgaacct
     9781 ttcgattctg aaaaattgcg cacgatacgt ctcaattgta cacattcagt ctgcgatagc
     9841 accaacaacc tgtaatactt cttttcgcgc ccgatcggga ttctcactgt caagccagcg
     9901 caccccttcc caaccgcgca accaggtcat ctggcgcttc gccaactgtc tcgtggagca
     9961 aacacctcta taaaccattt catcatatga gatttcgccc tcaatgtatg accacatctg
    10021 gcggtatccc acacaacgga tggaaggcaa gtccgtatgc aaatctcctc gggcaaaaag
    10081 cgcccggact tctgcttcaa aacctgaagc caacatctga tgaaaacgca gttcaatgcg
    10141 ctgatggagc agttcacggc tcgctggggc gatagcgaac tgatgcacct ggtacggtag
    10201 cgcgtctcct gacgtttgcg ttagctccgt taaagtttta cccgaaatga aaaaaacttc
    10261 cagtgcccgg gaaagtcttt gcggatcatt tggatgaatt cgcgcggcgg caaccggatc
    10321 tatctcctga agttgctgat gcaacgcctc ccatccaagc tccgctgctt gctgctctat
    10381 ccgggatctg acttccggat ctgctgaagg cagcggcgat aacccttcca gcaatgcctt
    10441 aaaatacagc atggtaccgc ccactaacag cgggatacgc cccgcagcgg tgatctccgc
    10501 catttgcgct aacgcgtcgc ggcgaaaatc cgccgccgaa tacgcctgcg acgggtcgcg
    10561 tatatccagc agtcgatgcg gcgccgcttt cagctcatcg gcattcggct tagccgtgcc
    10621 aatatccatt ccccgataaa tgagggcgga atcaacgctt atcaactcta ctggcaaaac
    10681 tttacgcagt tctatcgcca gcgccgtttt gccggaggcc gtcggcccca tcaaaaatat
    10741 cgccttaggc aggctcacct tgcttacatc attcatgctt cagggcgttc atcgccgaat
    10801 gtaaatcaac aggttgtaac aggccacccg gcggcgcttt taccagctgc ggacatagcc
    10861 gctcaacatc cgccagcagc gatatggcct gcgccatcga ccactgcgga tgttcgctct
    10921 gcacattacg cgctatccat tgtgcaatat tgaccgttgc aaatgtggtc tgttgcgcca
    10981 ggtagcctat cagttcagga atcaagattt gtaaattttg ttgtcgtaag ggtaaaggca
    11041 ccgcccgaat ggtcacatgc tgcgcatctg actgaaattc aatacccaat tctcccaaca
    11101 aagattgggc tttttgcagc gcggcttttt catcggcgct cacttttaaa cgcagcggaa
    11161 tcagcaacgg ctgcgcgcaa accggacttt gacccggtgt aagctgcgcc tgacgcagcc
    11221 aacgctccgc aaccggcagc gacaagagct ggatagtccc cgcgtgttcc agcaacgcgc
    11281 agtcaccgcc gactatcgtc agtacgcgac caaaactctg gctatgtccg tcaagcgcag
    11341 gcgcaaccgg ctccggcgcg gggctcgtcg tcggcgtctg taaaagcgtg cgataaacct
    11401 cgccctgctg cttctgatag cctggctgcg cgtgcggcca accacctgcg gactgacgcc
    11461 cgccgttacc gcccgatgcg ccgtcggaat aacgcggtgt cgcgggctcg cgcgccgcag
    11521 ttggctcggc gggtacagca aaatggttgc gcccggcggc gatacggttt tccgggacat
    11581 gccgcggcgc tggcgcaatc tcctccagcg gcagcgtcgt ttccgtctgc tgttgtagaa
    11641 cgctcagcac cccttgatag atgaagtcgt gcaccagccg cgattgatga aaacgcactt
    11701 cgtgcttggc gggatgaaca ttgacatcca cctgatgcgg gtcaatctcc agatacaaca
    11761 caaacgcagg ctgttggtcc gcgcccagtt tatcttcaca ggcctggcga atggcatggt
    11821 tgatcaagcg gtcgcgcatc atgcggccat tcacatagca gtactggatc tccgttaacg
    11881 ccgtggtggt gtgattcgga tcggcgaccc agccgcgcag ggtcagatcg ccatgctgcc
    11941 actcgatcgc cagtgcctgt tcgagaaacg gcgtgccgca gatggcgcct aaccggcgct
    12001 ctttttgccc gtcctttgcg acagcgcgat actgccgtac caatttgccg ttgtgcgaca
    12061 ggttaagcgt gacgtcaaaa cgggccaatg caatacgacg gatgatctca tcgatgtgat
    12121 taaattccgt tttttcggta cgcatgaatt tgcgccgggc gggcgtatta taaaagagat
    12181 ccagaacttc cagggtggtg ccgaccgggt gcgcggcggg ttttaccgtc acgtccatgt
    12241 cgcgcccttc cgcatacgcc tgccaggctt ccgcctgctc cgccgtgcgc gacgttagcg
    12301 tcaaacgcga gaccgaactg atactcgcca gcgcttcgcc gcgaaatccc agactgataa
    12361 tcgcttccag atcgtcaagc gaggcgattt tactggtggc atgacgggcc agcgccagcg
    12421 ccagctcctc ttttttaatg ccgcagccat tgtcgcgaat acgaataagc ttcgcgccgc
    12481 cacgctcgat gtcgatatca acgcgggtgg cgcctgcatc cagactattc tctaccagct
    12541 ctttaacaac cgacgcaggg cgttccacca cttcgccagc ggcgatttgg ttcgcaagct
    12601 gcggcggcag aacctgaatc ggcatgaaat ctccttaatt cgcggcggtt atagcgccag
    12661 gctggttggt actggccgtc tggcctgggc tgccctgcgg cgcagactgg atcggatgcg
    12721 ctgcaaagta cttacgcaac ccccggtata tagcgtcagc aatctgctgc tgatagcggt
    12781 cgctcgccag caatcgttct tcgccgtgat tactgataaa acccgtctcc accaaaatgg
    12841 acgggatatc cggcgaacgc agcacgccca ggctcgcgtg ttccgggcga cgtttatgca
    12901 gcgaccccac gccgtcgagt tggcttagta cgttcgtcgc cacatcatac cctacccgct
    12961 gcgaatgacc gaattgcaaa tccagtaccg cctggctcag gtaagggtct gactgactgt
    13021 tcgtcagcac atcgccagcg ccgcctaaca gttcggattg cttctcatgc tgctcaagcc
    13081 agtttgccat ttcgctattc gcgcgacgat tggacaatac ccagacggag gcgccggtgg
    13141 cgtcgcgatt tggcgcggca tccgcatgaa tagagacaag gaagttggcg ttttgcttac
    13201 gcgccacatc agaccgcccc atcaccgaaa taaaatagtc gccgtcacgc gtcagcacgc
    13261 ctttaaacat cggatcgtta ttcagcaatg tgcgtaactt acgcgcgatg gcgatggtga
    13321 catttttctc gcgcgtaccg cccgggccta tcgcaccggg gtcctggcct ccatgtccgg
    13381 catcaatagc aatcaccact ttatcgccag cgcctgccga cgcgcgcgcc gcaggccgcg
    13441 taacggtgtt gctgctggtt acgccggtca ggcgatcatc agaagattta aacggattac
    13501 gggcaggctc cgtcgggcgg ggcgcgcttt caacccgttt cgcgacgaca ggcggtggcg
    13561 gcggcggaac atcggcatta atggtgaaaa tgaccgtata gttgccgccg ttttgccgct
    13621 tcaccgcctc ggttttacca ttttccgtca gatcgacaag cagccgtaaa gattgcgcat
    13681 ctttcggcgt tccggcacgg atcgttttta ccagattgtt accgctaaac tgaagcggca
    13741 gcccctgaat cacgccggtc tgcctgatat ccagcgccac ggtccgttta ccgtcctgtg
    13801 agtaagcata ttccggctcg ccgataaaac tcagcgtaat gcgcgcctgc tgctcgccgt
    13861 tggacacctg aatatcagag agactggcgg cgcccgcctg cgcgcacagc aggattaagg
    13921 ctgctattac ggcatttttg atgcgataaa tcatcccgcc acctttatag ctaatcggct
    13981 aaacgcgcca gtaacgaatg acccgatgag gataccgcgc ttacgcgagc ctcacgcccc
    14041 tgcgcctggt aatcaatatg gatttcgacg tccgggtcgg ggagaacgcc tttaccttgt
    14101 tgcggccact ccaccagaca aatggcgtcg ttggcgaaat aatcgcgaat gcccataaac
    14161 tccagctcct ccgggtccgc aagacggtat aagtcgaagt gatataccat catgttatca
    14221 agcgcataag gctctaccag cgtataggtg gggcttttta cattaccgtt atggcctaac
    14281 gcctgtaaaa atccccggct aaacgtcgtt ttaccggcac ctaaatcgcc atacagataa
    14341 ataacggtcg cgccatcaca ggcgttggct acccgttgcc ccaggtctag cgtcgcctgt
    14401 tcgtcaggta gcggaattac tcgattcatc atggtttacg tcaatcacat cagggttaac
    14461 aatacgccgc agcgtagtaa aaagatcggt cgccaacatg ccgcgagcgc cataacgcgc
    14521 tgccagtaag tccgccgccg cgccgtgagc cacacatccc acacatgccg catcatacgg
    14581 ggtaaacttc tgtccgagca atgcgccgat gatgccggac aggacatcgc ccatcccgcc
    14641 gctcgccatc cccgcattac cagcgtcaat gatagccaga gggtggtgtt cagcggcaat
    14701 aatcgttcct gcgcctttta acacgaccac gcctccatac cgttttacca gacgctgtgc
    14761 tgaaagtaag cgatcacttt caatttctgc cacagaacat cctaacaggc gggccgcctc
    14821 tcccggatgc ggcgtaatca cgcgattgtg acgtttatca ggattgattg ccagtaggtt
    14881 caacgcatcc gcatcccaca gcataggttt acggacgttt tctactttct gtaaggcttt
    14941 tttgccccat tcctgctgtc caagccccgg gccgatcacc acaacgtcag cccaggtcag
    15001 gctctcttcc agcgactgag gcgtgagttc atgtaccatc agttccgggc gggccgtcag
    15061 caacgacgcg atgttttcac cgcgagtcag tactctgacc aacccagccc ccgtacgcag
    15121 cgccgcctcg ccagccatcc gaattgcacc cgctgttccc tgatcgccgc cgataatcgc
    15181 cagacgacca tgatcgccct tatacgaggt cggtcgacgc ggcgttaacc attgccccaa
    15241 ctgcgtcgcg tcaaaacgcc ggagcggcgg cgtctggctc gccagccagc cttccagccc
    15301 caacgcgtca taatgcaata tgccggtaac gtcacgcgct ttgccggtca gcaggcctgg
    15361 tttcagggcg ataaacgtga ccgtatgcgc ggcgcttatc accgcgccag gcgtggtgcc
    15421 cgtttgcgcc agcaggcctg acgggatatc gacggcgaca accggcgcag gatgggcgtt
    15481 cgcctgttca atcagaccgg ctaccggatc gcgcggctcc tgggctatgc cggtgccaag
    15541 cagcgcgtcg ataatcagat ccgtcgcttc cggccagata atatcggcag catggataat
    15601 gccgccggca ttcagccagg catcgcgcgc ctgcgccgct tcttcaggta acggtttgtc
    15661 gctctcctgc gccagcaacg ttacgctaat gcccgccgct tgcgctagtc gcgccacgac
    15721 gtaaccatcg ccgccgttgt tgccatgacc acacaacacc agccagtgtc gggcgtcagg
    15781 gtaactgtca cgggctaccc gaaatgccgc gtcgccagcg cgcagcatca attcatagag
    15841 tgtgagtccg aaggcatccg ccgcatcgcg ttccagccgt ttgatgtcat cggcgggcca
    15901 aatggagtgt ggtatactta cagggttttt cttcatgtta tggtccatca tgtcaaagcc
    15961 cctcgatctc aatcagttag cgcaaaatat taagcagtgg gggctggagc tgggctttca
    16021 gcaggtcggt attactgata ccgatctgcg cgcatccgaa cctgcgctgc aggcgtggct
    16081 ggacaaacaa taccacggcg agatggcatg gatggcgcgc cacggtatga tgcgcgcccg
    16141 gcctcatgaa ctcttacccg gtacgctacg tgtcatcagc gtgcgcatga actatctgcc
    16201 cgccaacgcc gcgtttgcca gtacgttgaa ggatcccacg ctgggctacg ttagccgata
    16261 tgcgctgggg cgtgattatc acaagctgtt acgcagccgt cttaaaaaac tgggcgagca
    16321 gatccagcag tactgcggtt cgctgaattt tagaccgttt gtcgactctg cgcctattct
    16381 tgaacgccca ttagcggaaa aagccggact tggctggacg ggtaagcact cacttatcct
    16441 taatcgggag gcgggctcat tctttttcct gggggaattg ctgattgatt taccgctgcc
    16501 ggtcgaccag ccggtcgagg aaggttgcgg caaatgcgtc gcctgtatga ccatttgccc
    16561 gaccggggcg attgtcgaac cgtatacggt ggacgcgcgg cgctgtattt cttatctcac
    16621 cattgagctg gaaggcgcta ttccggaagc atttcgccca ctgataggta accgtattta
    16681 cggctgcgat gactgccagc ttatctgtcc gtggaatcgt tactctcagt tgaccgacga
    16741 agcagatttt agcccacgca aggcgctgca taacccagat ttgcttgagt tgtttagctg
    16801 gagcgaagcg cagtttctga aagtcactga aggttctgcg attcggcgca ttggccattt
    16861 acgctggctg cgcaatgttg ccgttgcgct ggggaatgcg ccgtggagta atgccgtcat
    16921 tacggcgttg gaaagccgca agggtgagca tccacttctt gatgagaata tcgaatgggc
    16981 gattgcgcaa caaattgaaa agcggaacgc ctgcatcatt gaagtgcagc taccgaaaaa
    17041 acagcgtctg gtcagggtga ttgaaaaagg gctggtgcgc gatgcctgaa ttattcacag
    17101 gctgtgtata aaaataaaaa cacattgcga ttcaagaggg aaaaaaggaa cagacaataa
    17161 cgctaacgtt ttgaaatctt attttttcta tatttttcag taaattatag aaattctacg
    17221 cgtcaggtat aattttttgc attccaggag taatgggccg tcctgtggat aagtctgttt
    17281 acaaggatct gacgaaagcg gaacaaaacg tgccccaacg cgatattcgt tgtggataat
    17341 tttactgtag ataagaattg gagcgggaaa cgagactcga actcgcgacc ccgaccttgg
    17401 caaggtcgtg ctctaccaac tgagctattc ccgcataatc ttcgtctttc gaaccgctac
    17461 tgccttggct gccttcactc gcctgagtca cttacttcag taagctcctg aggactcatt
    17521 cagttgccgc cttgtcgcaa ttcgaaatcc tgcgattggt ggtttgtact taacaagtac
    17581 tttcaaattt tggagcggga aacgagactc gaactcgcga ccccgacctt ggcaaggtcg
    17641 tgctctacca actgagctat tcccgcaaat ttgttgctgt cgtaattcgc atttctgcgt
    17701 cgttacggga ggcgcattat acgagaaatc catttagctg caagcccctg aacgcatttt
    17761 ttcgcgattt ttgtttgaat gctgattaaa tcaccaaaca agacaaaaaa cgagcaaagc
    17821 gtgcgctatg caacaaaaaa cttttcacgc cacgcctaaa ggcacagaat cagaatagca
    17881 ccctgcgcca aaaaaagaat agcacggtga ccacaacatc caattgatat cagggatcaa
    17941 gatgaaaaaa aacttattgt catgctgtta gccagcctct ccgttcacgc tgcttccgtt
    18001 tccgccagaa cattacattt tggcacctcc gccacctatg cgccctatga gtttgtcgat
    18061 gccgataata aaattgttgg tttcgatatt gatgtcgcca acgcggtctg caaagagatg
    18121 caagcggagt gctcattcac taaccagagc tttgatagtc tgatccccgg cctacgtttc
    18181 aaaaagtttg atgcggtgat cgccggtatg gatatgacgc ccaaacgtga gcagcaggtc
    18241 tcctttagcc aaccctatta cgaaggttta tcggcggtag tcgtcacgcg taaaggggct
    18301 tatcacactt ttgccgatct gaaaggcaaa aaagtcggac tggaaaacgg tacaacgcat
    18361 cagcgctatt tgcaggataa acaacaagct atcacgcctg tcgcctatga cagctatcta
    18421 aacgctttta ccgatctgaa aaataaccgt cttgagggcg tgtttggcga tgtcgccgcg
    18481 attggtaagt ggctaaaaaa caatccggat tacgccatca tggatgaacg cgccagcgat
    18541 cctgactact acggaaaagg gttaggcatt gcggtacgca aaggcaacga cgcgctattg
    18601 caagaaatta atgccgcgct cgacaaggtg aaagcgtcgc cggaatatgc gcaaatgcag
    18661 gagaaatggt ttacgcagta attcagtggc gggagagctg ccggatgaga cgctctggcg
    18721 ttgccatccg gcatgttacg cctcacagct taatgaaatg ctcgcggtag taagccagct
    18781 ccgccaccga ctcgcgaata tcatccatcg cctggtgcgt gccctgcttg gtaaagccgg
    18841 ccagaatctc cggcttccag cggcgcgcca gttccttgag cgtactgaca tccagatagc
    18901 gatagtggaa gtaagcctcc agttccggca tatatttaaa cagaaaacga cgatcctgac
    18961 cgatgctgtt accgcaaatc ggcgacttac ccgcaggcac ccacgttttc agaaattcaa
    19021 tcgtcgccag ttcagcgtct cgttcgccca tcgtacttgc tttaacgcga tctaccaggc
    19081 cgctaccggt atgggtgcgc acgttccagt catccattaa cgccagttgc gcatcggatt
    19141 gatgtaccgc aatcgtcggc ccttccgcca gaatgttcag gctggcatcc gtcactagcg
    19201 tggctatctc aataatgcga tcgcgttcgg ggtccagacc tgtcatctcc agatcgatcc
    19261 aaatcaggtt gttttcatcg gcactcatgc tattttccac ccttcagagg tcacattcac
    19321 tgtgactata ttcatctaca attgcgtgta tcatagatgt tttgcccact atgggcgacc
    19381 aggagccagt acgattgagc aaaaataaac tctccaaagg ccagcagcgc cgtgtgaacg
    19441 ccaatcacca gcgtcgttta aaaacgtccg cggagaaagc cgactacgat gacaacctgt
    19501 ttggcgagcc tgcagaaggt atcgtcatta gccgttttgg tatgcatgcc gatgtggagt
    19561 ctgctgacgg cgaggttcac cgctgcaata tccgccgcac tatccgttcg ctggtgacgg
    19621 gcgatcgcgt cgtctggcgt ccgggcaaag ccgccgcaga gggcgtcaac gtaaaaggca
    19681 tcgttgaagc ggtgcatgag cgcacctcgg tattgacgcg cccggacttc tacgacggcg
    19741 tgaagcctat tgccgccaac attgaccaaa tcgttattgt ctccgcgatt ttgccggagc
    19801 tgtcgctgaa tatcatcgat cgctatctgg tcggctgtga aaccctacag gttgagccgc
    19861 ttatcgtact caataaaatt gatctgctgg acgacgaagg tatggacttc gttaatgagc
    19921 agatgaatat ctaccgcaat atcggctatc gcgtgctgat ggtctccagc catacgcagg
    19981 atggtctgaa accgctggaa gaagcgttaa ccggtcgcat cagtattttt gccgggcagt
    20041 ccggcgtcgg aaaatccagt ctgctaaacg ctctgctcgg cttacagaac gagattctga
    20101 cgaacgatgt gtcgaatgtc tccggtctgg gtcaacatac cactaccgct gctcgtctgt
    20161 atcatttccc gcatggcggc gatgtcattg attcccccgg cgtgcgcgag ttcggcttat
    20221 ggcatctgga gccggaacaa atcacccagg gctttgtcga atttcatgac tatttgggac
    20281 attgtaaata ccgggactgc aagcatgacg ccgatccagg ctgcgccatt cgcgaggcgg
    20341 tagagaacgg cgctattgcg gaaacccgtt tcgaaaatta tcaccgaatt cttgaaagta
    20401 tggcgcaggt aaaaacgcgt aaaaactttt ctgatacgga cgactgacag atacgctagg
    20461 cgtcgttaga atcgtcccct tttttcagga taccggtata actgccggtt caggaacaac
    20521 aatggcctgg aggctacctt gttaaactca tttaaacttt cgctacaata cattctgccg
    20581 aaactatggc tcactcgcct ggcgggctgg ggcgcaagca aacgagcagg atggctgaca
    20641 aaactggtta tcgatctctt cgtaaagtat tacaaagtcg atatgaccga ggcgcaaaaa
    20701 ccggataccg ccagctatcg tacgttcaat gatttctttg ttcgtccgct gcgtgatgac
    20761 gtgcgtccgc tcaataccga tcctaacatc ctggtgatgc ctgccgacgg cgtgataagc
    20821 cagttgggtc gtatcgaaga agataaaatt ttgcaggcca aaggccataa ttacagcctt
    20881 gaagcgttgc tggcgggtaa ctacctgatg gcggataagt tccgcaacgg cacgtttgtg
    20941 accacttacc tctcccctcg cgactaccat cgcgtgcata tgccatgcaa cggcatcctg
    21001 cgcgaaatga tctacgtgcc gggcgatctg ttctccgtta actatctgac cgcgcaaaac
    21061 gtccccaacc tgtttgcccg caacgagcgc gttatctgtc tgtttgatac cgagttcggg
    21121 cctatggcgc agattctggt cggcgcaact attgtcggca gtatcgaaac cgtctgggcg
    21181 gggaccatta ccccgccgcg cgaaggcatc atcaagcgct ggacctggcc agaaggcgaa
    21241 catgaagggt ctgtcgcctt gttgaaaggc caggagatgg ggcgctttaa actgggttcc
    21301 acggtcatca acttatttgc gccggggaaa gtgaatctga tcgcgtcgct ggcaagcctg
    21361 tccgttacca aaattggcca accgctggcg acgtcgaccg aaacattcgt cgcgccggag
    21421 gtggaacctg ctccgctgcc ggcagaagaa attaaagctg aacacgacgc cagcccgctg
    21481 gttgacaata aaaaagacga cacctaatca agagagaatg ctgacgtgcg cctgattatc
    21541 gcttttctga tggcctggtg cctcagcacg ggggcgttcg ccgcaacggc ccccgacgcc
    21601 aaacaaatca cgcaggaact ggagcaggca aaagcggcga aacccgctca gccggaagcc
    21661 gttgaggcgc tccagactgc gttaaacgcg cttgaagagc gaaaaggctc gcttgagcgc
    21721 gcgaaacaat atcaacacgt tattgataat ttccctaagc tatccgccac cttgcgcgcc
    21781 cagttgaata atctgcgcga tgaacctcgc agcgtaccgc cagagatgtc caccgaagcg
    21841 ttaaatcagg agatcttgca ggttagcagc cagctactgg ataaaacccg cgaggcgcaa
    21901 caggagcagg agcgcgtcag ggagatcgcc gactcgctca gccagcttcc ccaacagcaa
    21961 aacgacgccc gccgccagct taatgagatt gagcgacgac tcggcgccgc aggcggaagt
    22021 gccgcgctta gccaggcgca aagtctcagt atgcaggcgg agtccgccaa actaaaagcg
    22081 ttagtcgacg aactggagtt ggcgcaactg tccgccaaca accggcagga actggctcgt
    22141 ctgcgttccg agctggcgga aaaacagagt cagcaattgg atgcgtatct tcaggcgctg
    22201 cgcaatcagc tcaacagcct gcgtcaacgt gaagcggaac gcgcgctgga aagcactgag
    22261 ctgctggcgg aaaacagcgc cggtttgccg gaaggcatcg tcgaacaatt taaagtcaac
    22321 cgcgggctgt cacaggcgct caatcaacaa gcgcagcgga tggatctggt cgcctcgcag
    22381 cagcgacagg ccaccagcca aacgttacag gtgcgtcagg cgctcaatac gctgcgggag
    22441 cagtcgcaat ggcttggcgt gtccaacatg cttggcgaag cgctgcgcgc gcaggtcgcc
    22501 cgtctgccag agatgcctaa gccgcagcag cttgatacgg aaatggcgca gctacgcgtt
    22561 caccgtatgc gctatgaaga attactcaat aagcaaccgc agctacggca aatacgtcag
    22621 gccaatggac aaccactgac cgccgagcaa aaccagattc ttgacgccca gcttcgcact
    22681 cagcgcgagc tgctcaactc tttgttacag ggcggcgaca cgctgatcct ggagttgacc
    22741 aaactgaaag tctccaacag ccaactggag gatgcgctta aagaggttaa tgaagcgacc
    22801 caccgttatc tgttctggac cgctgacgtt agcccgctat cgctctcctg gcctgttgat
    22861 ttggttcagg atttacgtcg gcttatctca ttagatacgt ttaatcagtt aggtaaagcc
    22921 agcatcatga tgctgaccag caaagagacg ctactgccgt tattcggcgc gctggcgctg
    22981 gtcgggttta gcctctattc acgccaacac ttcaaccggt tccttgagcg ctcggcctcg
    23041 cgcgtcggga aagtcaccca ggatcacttc tcgctgacgc tgcgaacggt gttctggtcg
    23101 attctggtcg cctcgccgct gcccgtcttg tgggcgacgc tcggctatgg tctacaggaa
    23161 gcctggccgt atccgctggc cgtcgccatc ggcgatggcg tgacggcgac agtaccgctg
    23221 ttgtgggtag tcatgatttg cgccgctttt gcccgcccta atggtctgtt tgtggcgcat
    23281 ttcggctggc cgcgaaaccg ggtagcgaaa gcgatgcgct actacctgat gagcattggg
    23341 ctgatcgtgc cgctcattat ggcagtgatc atgtttgata atcttaacga tcgggagttt
    23401 tccggctcgt tgggccgcct ttgcttcatc ctgatatgcg gcgcgctggc gctggtcacg
    23461 ctgagtctga aaaaagcggg catcccgctc tatcttgata aagaaggcaa cggcgacaac
    23521 atggtcaaca gcctgttgtg gaatatgttg atgggcgcgc cgcttatcgc gattctggcg
    23581 gcggcggtgg gttatctggc cacggcgcag gcgctactgg cgagactgga aacctcggtc
    23641 gccatctggt tcctgttgct ggtcatttat cacgtcattc gccgctggat gctgatccaa
    23701 cgacgccgac tggcttttga ccgcgccaaa catcgtcggg cggaaatgct ggcgcagcgc
    23761 gcgcgcggcg aagaagaacc ggcgcactcc tccagcctgg aaggcgcggt cgacatcgat
    23821 gaaagtgaaa tcgatcttga cgctattagc gctcagtcgc tgcgtctggt tcgctcaatt
    23881 ctgatgctta tcgccctgct atcggtaatt gtactgtggt cggaaatcca ctcggcattc
    23941 ggcttcctgg agaatatttc gctgtgggat gtcacctcta cggtgcaagg cgtggaaagt
    24001 ctggagccga ttaccctggg ggcggtgctc attgcgattc tggtctttat catcaccacg
    24061 cagttggtgc gtaatctgcc tgcgctgctg gagctggcgt tattacagca tctcgattta
    24121 acgccaggta ccggttacgc catcacgacc atcaccaaat atctgttaat gctgattggc
    24181 gggctggtcg gtttctcgat gatcggcatt gagtggtcga agctacaatg gctggttgcc
    24241 gcgctcggcg ttgggcttgg ttttggcctg caagaaattt tcgctaactt tatctccggc
    24301 ctgattattt tgtttgaaaa gccgattcgt atcggcgata cggtgaccat tcgcgatctc
    24361 accggcagcg tgaccaaaat caatacccgc gccaccacca tcagcgactg ggatcgtaaa
    24421 gagattatcg tgccgaataa agcctttatc accgaacagt ttatcaactg gtcgctgtct
    24481 gactccgtta cgcgcgtggt gttaaccatc ccggcgccgg cggatgccaa tagcgaagag
    24541 gtgacgcaaa ttctgctgac ggcggcgcag cgctgttctt tggtgcttga taacccgccg
    24601 cctgaaatct ttctggtgga tctccagcag ggtattcaaa tttttgaact gcgtatctat
    24661 gccgcggaaa tgggacaccg tatgccatta cgccatgaga tccaccaatt gattctggct
    24721 ggcttccgcg agcacggtat tgatatgccg ttcccgccgt tccagatgcg tctggagagt
    24781 ctcggcggta aacaaacggg gagaacgtta acgtcagcgg gtaaaaccag ccgcccggcg
    24841 gggagtttgt agcgcatgat cccggcaaga aatgccggat gcgccccgtc gggtcttatc
    24901 cggcctacgg gccgacaatt aatctgtagg cccgataagc ttgcgccatc gggcatttca
    24961 tcgcaactca cagacatttt cggacttatt atgcgtccag atcggcaaca ggcaggttaa
    25021 tttcgctata gcgcattcgg aataaatcgc cgtaacccac cagttctccg cgaaatacga
    25081 ggcatcttac aacatacgcg caataaatat ccgacacatg tttccactta tcctcatcgc
    25141 gatcccttaa cgtgccaata gtcattccta ctaccatcgc aacctttcga cgtgcaacat
    25201 gaacggaaga aagaataacc ttttctattt caaggatatc ttccggagta aaattgagtg
    25261 ccctaatctc atcttccgtg ataatcgggt ctctcgaact atcattcatc acgttctcca
    25321 tagggcaata aacgccggat gcgacccgtg gggccttatc cggcatacgg cctttactcc
    25381 gccgcccact ccggatcagc gctcatgcgg ctgctgtaat tctgataaat cgccatcgcc
    25441 agcagcgaga agaagatcgg gccgccgatc atccacaagg cgctgtccca gtccccagct
    25501 tcaatcactg gctggatgat ggtaaagacg ttggcaaacg tcaccaccag caccacaaca
    25561 cccgtcgcga ccagggtaga ggctttggtt ttaaagagaa caaatggccg ctccagatcc
    25621 tgacgcgctt taaagaaggg aaatgccagc gcaaggaaca ggtatggcaa ggtcattgag
    25681 acgttcgcca tcagcgtgag tttgttataa aacgccgatg cggtgtcacc gccaaaagag
    25741 accagcaaaa taaacagact caccagcacg cactgtagcc acatagcggt cgccggcata
    25801 ccgttagcgt tcagtgtcgt catcggcgcg ggccacaacg cttttggcgt cccctgaata
    25861 atggctttca gcggtgaata gctcaacgta aaaaacgcgc cggtataagc cagaaacata
    25921 gaaaggccgg tgatacgcgc aaaccagacg cccaccgtca tcgcagcttc cggagaaagg
    25981 tttaacgcgt tacctaatgt cgtgcctaaa ctcgacatca gaatgtaggt gatattccct
    26041 aagttaacgg cgctattact taatatctgt tgccagttag tactgacgcc ccataaaaag
    26101 atcgccaaag aataaccaat tgaaatcaca atggccgcga aaacaatacc tttcgcaaaa
    26161 ttcttttccg gtttctcggt tttatccacc agtccgccga cagcctcaat accgccgtaa
    26221 gcaaaaatag caaataccac aaatgacaac attgccaggc cggagtgata acccggattc
    26281 ggtgacgagg taaaattaat ctcttgtgca aaatgcccac catttaataa caaaatagcg
    26341 acactcacta acaataaaac taaattaaga cacattacgg caatacctcc gaccgccgta
    26401 attcgcgcaa ttttattgat ccctctggcg gcgacacacg tcaccagaat catccagccg
    26461 acggcgagca gcccgacaac ctgcgtaggc tcaagccctg caatacgcca gtgctgcgtc
    26521 atatcggcgc caaaaacaaa agtagaaaac ggtacccaaa tttttgccgc cgtacttacc
    26581 atccatatga catacgatga aaaccacata aacgtgccaa taaacgcgta acgtggcccc
    26641 acgctattat tcatccacga atagatcccg ccctcttctt tgcgataagc ggaacccatt
    26701 tcagccatca ttaaggcgaa tggaataaaa aacagcaagg cagaaaatat ataccacggg
    26761 attgcgctat accccattaa ataaaacgcc gacgggctat tcgcaaaacc aaaaacagaa
    26821 gtaaaaatca tcaggataag cccaataagg ctcatctttt ttatcgtgtg ggtcattcaa
    26881 ccatccctta cgctcgagcg cgtttgccag acgccgctca ccgattgacg ccgccttctt
    26941 ttttacgaag gtcagcgata aaaaaatcaa cacaggattg atacctaaat ggcatcaaag
    27001 ttccagcctt atgttgtggc aaacagagga taattgaaaa aatatgctac aaaatggcgc
    27061 ttatttcgcc attttatctc gcgaaagagt gaatttcaga tttacgcccg atcgaccgta
    27121 aaagcaatca cgtccgccag gctttctgct cccagcgcca gcatcaccag acgatcaaca
    27181 cccagcgcca cgccggaaca atccggtaga ccggcggcca gcgcatccag tagattttgg
    27241 tcaatcggct gctgcggcag accgcgcgcg gcgcgcttac gattgtcctg ttcaaagcgc
    27301 tgttgttgct cacgtgcgtc cgtcagttcg tggaaaccat tcgccagctc aatacctttg
    27361 tagtacacct caaagcgctc ggcgacgcga tgatcctcgg tactgatttg tgccagcgat
    27421 gcctgactgg ccggaaagtg ataaataaag gtcggctttt ctttacctat atgcggctca
    27481 acccccatcg tgaacagcag ttgcagcaac gtatcacggt cttcttccgt atcggcgata
    27541 ttgcttaaat caagctttgc cgccgcctca cgcagctgcg ttttatctgc tgataacggg
    27601 tcaatctcca gatggcgcag aaacgcctgt tgataggaga gactttccgc aggttgacaa
    27661 tccagcactt gctgaagcaa atcatccact tcattcatca ggcggtacat atcgtaatgc
    27721 gggcgatacc actccagcat ggtgaattcc ggattatgat gtcgtcccat ctcttcatta
    27781 cggaaactgc ggcatagctg gaaaaccgga ccgcaccctg ccgccagcag gcgtttcata
    27841 tggtattccg gactggtcat taaatagagg ttgatcccct gggaatggcc aggtccgacg
    27901 aaacgcgttt cgaacgggaa cagatgaatg tctgtgaccg tcgcctgact catgcagggc
    27961 gtctcaacct caagcactcc acgatcggca aagaaacgac ggatttccgc cataatcgcc
    28021 gcacgtttta ataaattggg gatggacgcg ctcggctgcc aggttgccgt ttcgctcatg
    28081 attctttctc cagtttaaga caaggtcacg aagtctactc gcaacgcgcg ggcgaaacaa
    28141 attttgcgca ggcgtatcgg gtgccttctg gagggtaaaa aaagtgattt cagatggttt
    28201 agtaattaaa ttaatcaaaa tcaatgataa ttcatccctc tgatacgcta aaaaaatcga
    28261 acacgtcaaa tttccctcac atccctgaga ctatactgtt gtacccataa aggagcagtg
    28321 gaaacgcatt catacttcgc agaacccaga ggctttatct ggctgcgcga gggtgaaatt
    28381 acaataatct ggaggaatgt cgtgcaaacc tttcaagccg atcttgccat tataggcgct
    28441 ggtggcgcgg gattacgtgc tgcaattgct gccgcacagg cgaatcccaa tgctaaaatc
    28501 gcactgatct caaaagtgta cccgatgcgc agccacaccg tcgctgccga agggggttca
    28561 gccgctgtcg cccaggatca tgacagcttt gactaccatt ttcacgatac ggtagcaggc
    28621 ggagactggc tgtgtgagca ggatgtcgtg gattactttg tccaccattg tcccactgag
    28681 atgacgcagc tggagcaatg gggctgcccg tggagccgcc gtccggacgg tagcgttaac
    28741 gtgcgtcgct tcggtggtat gaaaatcgag cgtacctggt tcgccgcgga taaaaccggc
    28801 ttccatatgc tgcataccct gttccagact tccctacagt tcccgcaaat ccagcgcttt
    28861 gacgaacatt ttgtgctgga tattctggtt gatgacaacc atgcgcgcgg cctggtggca
    28921 atgaacatga tggaaggcac gctggtacaa atccgcgcca acgccgtggt catggcgaca
    28981 ggcggcgcag gccgcgtata ccgctataac accaacggcg gcatcgtcac cggcgacggg
    29041 atgggcatgg cgctgagcca cggcgttccg ctgcgtgata tggaattcgt tcagtatcac
    29101 ccgaccggcc tgccaggttc cggtatcctg atgactgaag gttgccgcgg cgaaggcggt
    29161 attctggtca ataaaaatgg ctaccgttac ctgcaagact acggcatggg ccccgaaacg
    29221 ccgctgggcg agccgaaaaa caaatatatg gaactggggc cgcgcgacaa agtatcccag
    29281 gctttctggc acgaatggcg taaaggcaac accatctcca cgccgcgcgg cgatgtggtt
    29341 cacctcgacc tgcgtcatct cggcgagaag aaactgcatg aacgtctgcc gttcatttgc
    29401 gaactggcga aagcctatgt cggcgtcgat ccggttaaag aaccgattcc agtacgtccg
    29461 accgcgcact acaccatggg cggcattgaa accgaccaga actgtgaaag ccgtgtcaaa
    29521 gggctgtttg ccgttggcga atgctcctct gttggcctgc atggcgcgaa ccgcctcggt
    29581 tccaactcac tggcggaact ggtggtgttt ggtcgtctgg ctggcgaaca agcaatggaa
    29641 cgcgctgcta cggcaggcgc cgcaaatagc gccgcgctcg acgcccaggt tgccgatatt
    29701 gaacagcgtc tgaaaaatct ggtgaaccag gaaggcaacg aaaactggtc gaagatccgc
    29761 gatgagatgg gtctgtctat ggaagaaggt tgcggtattt accgtacccc ggaactgatg
    29821 cagaaaaccg ttgataaact ggccgagctt caggaacgtt tcaagcgcgt acgtatctcc
    29881 gatacttcca gcgtgttcaa cactgacctg ctgtatacca tcgaactggg tcatggtctg
    29941 aacgtggcgg aatgtatggc gcactctgcg ctggcgcgta aagagtcccg cggcgcgcat
    30001 cagcgtctgg atgaaggctg taccgagcgc gacgatgtga acttcctcaa gcacaccctc
    30061 gccttccgcg atgctgatgg cacgacccgc ctggaataca gcgacgtgaa aatcaccacc
    30121 ctgccgccag ccaaacgtgt ttacggcggt gaagcggaag cagccgataa gaaggagaag
    30181 gcgaatggct gagatgaaaa acctgaaagt tgaggtggtg cgctataacc cggaaaccga
    30241 taccgcgccg cacagtgctt tctatgaagt tccttatgat gaaacaacat cgctactgga
    30301 cgcgttgggc tacatcaaag ataacctgtc gccagacctg agctaccgct ggtcctgccg
    30361 tatggcgatc tgcggctcct gcggcatgat ggtcaacaac gttcctaaac tggcgtgtaa
    30421 aaccttcctg cgcgattaca ccaacggtat gaaggtggaa gcgctggcga acttcccgat
    30481 tgagcgcgat ctggttatcg atatgacgca ctttatcgaa agcctggaag cgatcaaacc
    30541 gtacattatt ggcaactctc gcacgccaga tcaggggccg aatgtccaga ccccggcgca
    30601 aatggcgaag tatcaccagt tctccggttg catcaactgt ggtctgtgct atgccgcgtg
    30661 cccgcagttc ggtctgaatc ctgagtttat cggaccggct gcgattacgc tggcgcatcg
    30721 ctataacgaa gatagccgcg atcacggtaa gaaggagcgt atggcgcagt tgaacagtcc
    30781 gaacggcgta tggacctgta ctttcgtggg ctactgctcc gaagtctgtc caaaacatgt
    30841 cgatccggct gcggccattc agcagggtaa agtggaaagc tcgaaagact ttcttatcgc
    30901 caccctgaaa ccacgctaag gagtgcaaca tgacgactaa acgcaaaccc tatgtgcggc
    30961 cgatgacgtc cacctggtgg aaaaaactgc cgttttatcg cttttatatg ctgcgcgaag
    31021 gcacagcggt gccggcagtc tggttcagta ttgaactgat tttcggtctg tttgcgctca
    31081 aacacggcgc ggaatcctgg atgggattcg tcggcttttt acaaaacccg gtggtagtga
    31141 tcttaaacct gatcaccctg gcggccgcgc tgctgcacac caaaacctgg tttgaactgg
    31201 cgccgaaggc ggccaatatc attgtaaaag acgaaaaaat ggggccagag ccaatcatca
    31261 aagggctttg ggtggtcact gcggtagtca ccgtagtcat tctgtatgtt gccctgttct
    31321 ggtaaggagt cccggatgat taatccaaac ccaaaacgtt ctgatgaacc cgtattctgg
    31381 ggactgtttg gcgcaggcgg tatgtggggc gcgatcatcg cgccggtgat cgtgctactg
    31441 gttggcatca tgctgccgct ggggctattt ccgggcgatg ccctgagttt tgagcgcgta
    31501 ctgacgttcg cccaaagctt tattggtcgc gtttttctgt tcctgatgat cgtgctaccg
    31561 ctatggtgtg gcctacaccg tatgcaccac gcgatgcatg acctgaaaat ccacgtgcct
    31621 gcgggcaaat gggtcttcta cggtctggcg gcaatcctga ccgttgtgac ggcgattggc
    31681 gttatcactc tctaagttgc cacgacgccc tcttatctac ccgataagag ggcatttttt
    31741 cttttcctgc ctctcatttt cccgccaggt tctacactta gaaaaaacac tggaaggaaa
    31801 aacgctatgc gcttgctgcc cgtcgttgct gcggttactg cggcattttt ggttgtcgcc
    31861 tgtagttcgc ctaccccgcc taaaggcgtt accgtggtaa ataactttga tgccaaacgt
    31921 tacctcggca cctggtatga gatcgcacgc ctcgatcatc gatttgaacg tggactggaa
    31981 caagtcacgg ccacctatag tctgcgtgac gatggcggga ttaatgtcat caataaaggc
    32041 tataacccgg ctcgggaaat gtggcaaaaa acagaaggca aagcgtattt taccggtagt
    32101 ccaaaccgcg ccgcgctcaa ggtctctttt ttcggcccgt tctacggcgg ctataacgtg
    32161 attgcgcttg accgggaata ccgtcatgcg ctggtgtgcg gcccgaatcg cgactatctg
    32221 tggatactct ctcgcacgcc aacgctttct gaggaaataa aacagcaaat gctggccgtc
    32281 gcgacccggg aggggtttga cgtcaataaa ttaatttggg taaaacaatc aggttcgtag
    32341 caatgtcagc gacgaattaa tgcgcactga gttttagccc aatgataccc gcgacgatca
    32401 agccaagact gagcaaacgc gccggtgagg cagactcgcc cagcagaagg ataccggtga
    32461 ttgccgcccc aacggcgccg atgccggtcc agatggcgta cgccgttcca acaggcagcg
    32521 ttttcattgc ccaggaaagt aacgccatac tgataaccat ggccgtaatg gtgataatac
    32581 tgggggtcag acgagaaaaa ccgtgggtat acttcaggcc gacagcccat accacttcaa
    32641 gtaaaccagc gattaataaa atgatccagg acatagcagg ctccagataa ttaatggggc
    32701 cgtccccggt gagaatagcg tttacaggtc gtcctgtaac gtatacggat gaaaagccat
    32761 tcttgcctga gagaaaatga atttcaacct ttttattttt ttccgtctaa aggcgggaat
    32821 tggccctttt aagccgcgta gttttcgcat ttagcgccca caggagttct ctatgatgga
    32881 acgccttctg ggaaagaaag tgctttacta cttccgggta caaaaaacta tgttgaaaat
    32941 tttagtgata gaccgatgcc actttacccg tacgggcatg gaggcctggc ttaatcacac
    33001 tgatgtgctc agttcttcac tgctggtatc cgggatgaat aaccttatac tggcgaaaga
    33061 acatattctg caatggaagc cccatctggt tatcgctgat ttatatggtt ttctcaacga
    33121 tgccttaccc gagcagccta tcaatgcatt ttttgccgcc tgcaggatga cgccgttagt
    33181 attattacag tcagggaata tgccgtacag atcgcaatat gccagccatg cggtgttatc
    33241 taaacacacg cctttacatg agcttgcaca acgaattaaa ggagcgctat atactcatcc
    33301 actgcaggaa gcgccggaaa gcgccacgcc attgctctct ccgcaggagg aaaaagtgct
    33361 cgcgatgtgg acggaaggca ccagcaataa agagattgcg tatgcgcttg gcattcacgg
    33421 aaaaacggtt tacacctata agcgtaatat ccgtatgaaa cttcatatgg ataaccggta
    33481 ttctcccttt cttatgcttc cggagaaaat cgattaacgg tacgacgcca tgccgtaccg
    33541 ttgatgatta ctgctgagct ctggttgcag cgccagagat cgcactacca ccgtccgaga
    33601 tgtcctcgcc cacgccgcgc gtggtattac aagcagttaa tacagtggaa agtaccaaaa
    33661 cagaaaagat cgctgcaatt gtctttttaa ccataatgtc ttccttttct agccaatgtt
    33721 gtttgtgtat agcaacttaa taatagacaa catcccagaa aatgacgggc gatcgactaa
    33781 ttttaggaag acgagaagcg attagctggc tgcgcgggag atggcgtggc caagatgctg
    33841 aatatcttcg ccgaagccgc gggcggtatt acatgccgtt aataatgtgc cggtaagaag
    33901 aaccagcgcg acaaggccga taaagcgttt catcattgag gcgcgaaaaa taggatggcg
    33961 cagcatacgc tgcaccattt ttcccgataa cgtaaattat tttacgcggg atacgtattc
    34021 gccggaacgg gtatcgactt tgatcacttc gccaatctgc acgaacagcg gaactttaac
    34081 cactgcgcca gtagacagcg tggctggttt gccgccagta cctgcggtat cgcccttcag
    34141 acctgggtcg gtatcaacaa tttccagttc aacaaagttc ggcggagtga cagagatagg
    34201 ctgaccgttc cacagggtta cgatgcattc cgcctgatcc aacagccatt ttgcgttgtc
    34261 gccaatagcc ttggcatctg cagacagctg ttcgaaggtt tcgttgttca tgaaatgcca
    34321 gaactcacca tcgttgtaca ggtaagtcag gttcatatcg actacatccg cgccttcagc
    34381 ggaatcggtc gatttgaagg ttttctcaac gcgcgtgccg gtcagcagac ggcgcagctt
    34441 aacgcgggca aacgcctggc ctttacccgg tttcacgaat tcactggatt caaccgcata
    34501 aggttcgcca tccaacatga ttttaagacc ggaacgaaaa tcgttgctat agtaagtcgc
    34561 cataaggccc tctgaaattg ttaactggta gctaagccac aaaatggcgc atattgtaac
    34621 cctaaatacc ccattgcgag aagattggtt agcgcaactt gccgatgttg tgaccaatcc
    34681 cgacgaactg ctgcatcttt tacagattga agctgatgaa aacctccggg caagacagga
    34741 cgccaggcgc ttgtttgccc tccgcgtgcc gcgcgctttt attgcgcgca tggagaaggg
    34801 caaccctgac gatcctcttt tacgtcaagt gctgacgtcc cgggatgaat ttattgtcgc
    34861 ccccggtttc tccaccgacc cgctggaaga gcaacacagc gtggtgccag gattattgca
    34921 taaataccaa aaccgggcgc tattgctggt aaaaggcgga tgtgcggtaa attgccgcta
    34981 ctgtttccgt cgtcacttcc cgtatgcgga gaatcaaggc aataagcgca actggacagt
    35041 cgcgctggag tatatcgccg cacacccgga actggatgag atcatctttt ccggcggcga
    35101 tccgctgatg gcgaaagatc atgagctgga ctggctgctc acgcaactgg aagccattaa
    35161 gcacgtcaag cggctacgca tccacagtcg gttgcctatc gttatcccgg cacgcattac
    35221 tgacgaactg gtcgcccgct ttgaccagtc atgtctgcaa attttgttgg tgaaccatat
    35281 caaccacgcc aatgaagtgg acgaggcgtt ctgcctggcg atgaagaaac tgcgccacgt
    35341 gggcgtcacg cttctcaacc agagcgtcct gctgcgtggc gtgaatgata acgcgcaaac
    35401 gctggcgaat ctgagcaacg cgctatttga cgccggcgtg atgccctatt acctgcatgt
    35461 gctggataaa gtgcagggcg ccgcgcattt tatggtcacc gatgacgaag cccggcaaat
    35521 catgcgcgaa ctgctcacgc tggtatccgg ctatatggtg ccaagactgg cgcgtgaaat
    35581 cggcggcgaa ccgagcaaaa caccgctgga tttacagctt cggcagtgct aatcctcgcg
    35641 ggcgcgtcag ggacgacgaa aaatattacc gcgcaatatc acgaggagat tcccccgcga
    35701 ttctcctcac cctctggcga ggataaacta accttcgtta aatacacctt tccgatactc
    35761 tcttttcaat aaagtccgtt ttaggactcg cttagcgtgt actgcatttt cgaattatac
    35821 tggttctcct ttttatagga cggcataaac aatttatata tcaaatacat tgcagtaaaa
    35881 catttaatta ttttatattt gtggagaatt gacatggcct taacgattaa gggactaaat
    35941 accggcgtta ttcgtcacaa tgataagttt atcgcgctgg cgcttaaggt gaagtcactg
    36001 agaaataaag aaacactgct tttctttcct gtgctcgcgc tgcgagactt gttgatcggc
    36061 cttgaacacc ggctttattt acaatactcg cttccggaac aagagcagga aaaacgccag
    36121 aaagccaaaa gcagtcatgt gcttaaaatg catgagaata ttccggcaat actccgtgaa
    36181 gagctggaaa acgccgatgt taatcagcgt gttgaatctt tagcgttgag cgataataca
    36241 gaaaaagtat taacctttac gttaaagctg cacaatggta gccatcttga tttacaggtc
    36301 ggtgagtggc aggttgaagt tctggtgatg gctattattc acgccattaa taatgccgaa
    36361 atgcgtgagc tcgcattgcg tatttcttca atgctggact ttttaccatt atacgatgct
    36421 gactgcctgg ataacggtaa tatcgaattc gatacctata accagcctga ctggaaacat
    36481 aatctgtata accattattt agcgctcgtt tatcgttata cggatgaggc aggacaatcg
    36541 catgattgcg gcaccatcat taagacccgc agtcagtcag gctctaaaga agctgaagcg
    36601 atatcacgcc gcttgctgaa tttcagcccg cgtcttaaaa agctggaagg aaaaccgtgt
    36661 aaggtttttg tcagaacgct tggaaccggt aaagcagcgc gtctgacgca agatcaatgt
    36721 atgcgcgcgt tgcataatct acgcatggcg tcatcgcagg aaaaacgcta accatatcgc
    36781 cctctgaatc tttcagaggg cgttacgatt cagacatgtc aattcggaca tttataaacc
    36841 tggccgttca tctcgctggc cgtcgggaca aaactggaca acatgccctg cgacggacta
    36901 cttacgccat acagcacgtt tccacccatc gcggccgcct gattacgcag atcgttcgct
    36961 gcgccacgca ttgagccacc ctcttcgccg tgctggcctg aaaaccagtt actctgttta
    37021 ccagttgccg taccaataag ctggcattcc gcgcccggct tatcttcgac aaagcgtaca
    37081 ttttggccgg cagcggtgag ttcgttgctg gagctacaac ccgccatcag cagcgcggcg
    37141 ccaacgatcc ctgctaaata tttcacgtgc atgttattcc ccataatcaa tgagctggac
    37201 gttttgtccg tatctgaatc ttatactaaa aagatgacta aaagaaaaac ccccggtcat
    37261 ttctgcccgg gggtttctca attctgggag ataagcaccc aaatcattct ggttgcagga
    37321 aggcggccag tttgttaatc cccagtcact tactcaagta agtgactggg gttagccaac
    37381 gcatctgcag cctgaaggat gcagggggtg ggcaattaca tcatgccgcc cataccaccc
    37441 ataccaccca tgccgccagc agcgcctaaa tcaggagcat cgcttttcgg caggtcggtc
    37501 accatgcact cggtagtgat catcagacca gccacagaag ccgcgtattg cagcgcagaa
    37561 cgggtaactt tggttgggtc caagataccc atatcgatca tgttgccgta ttcttcagtt
    37621 gctgcgttgt aaccgtagtt accgtcgccg cctttaacgg tgttagcgac aacagacggc
    37681 tcttcgccgc agttcagcac gatctgacgc agcggagctt ccattgcgcg cagcgcaact
    37741 ttgataccca cgttctggtc ttcgttctgg cctttcaggt cagcaatttt agaagcaacg
    37801 cggatcagcg caacgccacc accagcaacc acgccttctt ctaccgcagc acgggtcgcg
    37861 tgcagggcat cttcaacgcg ggctttcttc tctttcattt caacttcggt cgcagcgcca
    37921 actttgatta ccgcaacgcc gcctgccagt ttcgctacgc gctcctgcag tttttcacga
    37981 tcgtagtcgg aggtcgcttc ttcaatctgc tgacggatct gagcaacacg gccctggatg
    38041 gcagcttctt cacccacgcc atcaatgatg gtggtggtgt ctttgttgat cacaacacgt
    38101 ttcgcctgac ccaggtcttc cagggttgct ttttccagct ccataccgat ctcttcagag
    38161 attacggtac cgccggtcag ggtagcgata tcctgcagca tcgccttacg acgatcgccg
    38221 aagcccggtg ctttaaccgc agccactttc acgatgccac gcatggtgtt cactaccagg
    38281 gtagccagcg cttcgccttc aacatcttca gcgatgatca gcagcggttt gcctgctttt
    38341 gcaacggctt ccagaaccgg cagcatttcg cggatgttgg agattttctt atcagccagc
    38401 aggatgaacg ggctttccag ttctactgcg ccagtttccg gcttgttgat gaagtaagga
    38461 gacaggtagc cgcggtcaaa ctgcatacct tcaaccacgt ccagttcgtc ctgcagaccg
    38521 gtaccgtctt caacagtgat gacgccttct ttaccgactt tatccatcgc ttccgcgatc
    38581 agtttaccta cggtttcgtc ggagttagcg gaaatagtac ctacctgagc aatcgcttta
    38641 gagtcggagc acggtacgga cagcgccttc agctcttcaa ccgcagcagc aaccgctttg
    38701 tcgataccac gtttcaggtc catcgggttc atgcccgcag caacggcttt caggccttcg
    38761 gtaatgatgg actgcgccag tacggtcgcg gtggtggtgc cgtcgcctgc agcgtcgttc
    38821 gctttagagg caacttcttt caccatctgc gcgcccatgt tttcaaactt gtcttccagc
    38881 tcgatttcac gcgctacgga aacaccatct ttagtgatag tcggcgcacc gaaagattta
    38941 tccagaacca cgttacggcc tttcggaccg agggttactt tcactgcatc tgccagtacg
    39001 tttacgccgc gcagcatttt cacacgagcg tcgttaccga attttacgtc tttagctgcc
    39061 attttctctt tcccttaaat tcgtatgttc agtgtcgttc gcggattacg cttcaacaat
    39121 tgccagaatg tcgctttcag acatgatcaa cacttcttca ttgtcgatct tttcagattt
    39181 cacaccgtag ccatcgttaa aaataacgat gtcgccaact ttcacgtcca gcggctgtac
    39241 agtaccgttg tccaggatgc gacccttacc gacagcgatg atttcgccac gagttgattt
    39301 acccgctgcg gaaccggtca gtacgatgcc gccagcagat ttggactcaa cttctttacg
    39361 tttgacgatc acacgatcat gtaacggacg aatactcatt gatagctctc ctttgagaaa
    39421 gtcattatca gttatgggtg acgccggccc gtaaacggtt tcccggctgg tgaccagaga
    39481 gatggggatg gggttttgcc ccttcaaggg gggagatgaa aaaaaattct tctgagcgaa
    39541 aaaagcggta aaaacgctac ttatctcacg tttacccaag gtttagaaca tcctgctata
    39601 agaaaaggcg tgtgtgatac gcttaaaaat gtctgtcgtc acctgacgtt acaatgccgc
    39661 cggataatga gctgatgaat gaactaaaaa aagagcttgg gttggttcag ggcgttatct
    39721 tgttaaccac atcattatta gggactggcg tttttgcgct tccggagctg gctgcgctgg
    39781 cggcaggcga catcagcctt tgggcatggc cgctgctcat tattttgatt ttccctattg
    39841 cgattgtctt tgctgtgctg gggcgtcatt ttccacacgc tggcggcgta gcgcattttg
    39901 tcgggatggc atttggcccg cgtctgcaac gggtgatcag ttggctgttt ttatcagtca
    39961 ttcctgttag ttttcccgca gccttgcata ttgcggtggg tttcggccag gcgctgtttg
    40021 gctggcaaag cgaacagctc ttatttgggg agctgggtac tctaggtttg ctatggttta
    40081 tgggatcgcg cggcgccagc tccagcgcca acctgcaagc cattatcgct ggattaatta
    40141 tcgcgcttat tgccgccatt ctgtggaaag gcgcgattaa acctgcagat atcaccttcc
    40201 cagccgcaaa cgaaatcatc ttttcccggc tgtgtaccgc cctggcgatc atgttctggg
    40261 gatttgtggg aattgaggct tttacgcatt tgtcgtctga atttaaaaat cctgaacgtg
    40321 attttccgcg cgcattgatc attggcctga tgctggccgg cgccatttat tggacctgta
    40381 ccgccgtggt gctgcatttt ggcgtctata gcgacaagat agcggcaaca gcatcgctac
    40441 cgcttattat tgttcatctc ttcggtatcc aggcgttgtg gatagcctgc attattggtt
    40501 atctcacctg ctttgccagc ctgaatatgt atgctcagag ttttgcgcgt ctgatatgga
    40561 cgcaaatgca atatcagccc gatcactatc tggctcaact ctctcccggg cgccttccct
    40621 tgcacgcgtt aaacgttatt ctggcctgtt gttgcgtgag ttccctggtc gtctacgccc
    40681 tgaagattaa cctcaatgcg ctgatcgtct atgctaacgg tatttttatt atgctctatc
    40741 tactttgtat gctggcgggc tgtcgactgt tgaaagggcg ctgctatgca ctggcggtga
    40801 cgggttgtct actgtgcctg ttattgctag taatgctggg gtggaaaagc ttatatgcca
    40861 ttattatgct ggcagcatta tggctgtttt taccgaagcg aaaacgcatg gcgtaagacg
    40921 tatctgttgg ccggataacg cctcacgcga cttatccgac cagcatctct acctttaatc
    40981 ccgacgatcg tctttatgtt caatacgatc gcgatcgtca tctttacgct gatactcgcc
    41041 gtcaaatgtt tcgccaccgc cagtacccgc gctaaacccg ccgcccggca tccgggaaaa
    41101 acgtaaatgc ggcagcaact tcagcgtcaa atgtttttgc actggcggta acaaaaggag
    41161 aaggccgaga aaatcggtga aaaatcccgg caacaggagc agtaagccag cgatgatcag
    41221 cgatacactc ttaatcattt ctgccgccgg gctctcaccg gccgccattt tttgttgcat
    41281 cagcaaaaag tttttaaaac cctggttacg taccagcgac ataccgataa cagacgtaaa
    41341 aatcaccagg attagcgtca tcaggacgcc aagcacatgg gcgacctgga taaagataga
    41401 aatctcaatg taaacataga gaaagacagc taaaaagggt atccagcgca aaggactctc
    41461 ctgtaagtca tggccgtctg cgacgaccat ttaaatgggg ttgcgattcg catcgattcg
    41521 atatggtggt gcgtagcaaa atttcaagtg gtttgtacac ctattttagg tagtaatact
    41581 aaagcggtga cctatttcac aaaataataa ataaggggta aattcccaca ctttaagtga
    41641 tccagattac ggtaggaatt ctgaaccagc atatgatctc gtttatcagg ccgatggagg
    41701 ggataatcgt cggtcagaaa acattcgaaa tcacatatat cctgtgtgtt ttaaagtaaa
    41761 aatcattggc agcttgaaaa agaaggttca catgtcaaac aacattcgta tcgaagaaga
    41821 tctgttgggt accagggaag ttccagctga agcctactat ggtgttcaca ctctgagagc
    41881 gattgaaaac ttctacatta gcaataacaa aatcagcgac atccctgaat ttgtgcgtgg
    41941 catggttatg gtaaaaaaag cggcggcgct ggccaacaaa gagctgcaaa ccattcctaa
    42001 gagtgtggcg aatgccatca ttgccgcatg tgatgaagtc cttaacaacg gtaagtgcat
    42061 ggaccagttc ccggtagatg tctaccaggg cggcgcgggc acttccgtca acatgaatac
    42121 caacgaagtg ctggccaaca tcgggctgga actgatgggt catcagaaag gtgaatatca
    42181 gtacctgaac ccgaacgacc acgtgaataa atgtcaatcc actaacgacg cctatccgac
    42241 aggcttccgt gtagcggttt acgcctctat cgtcaaactg atcgatgcca tcaaccagtt
    42301 gcgtgaaggt ttcgaacgta aagcggttga attccaggac atcctgaaaa tgggtcgtac
    42361 ccagttgcag gacgccgtac cgatgacgct tggtcaagaa ttccgtgcgt tcagcattct
    42421 gctgaaagaa gaagtgaaaa gcatcgagcg tactgctgag ctgctgctgg aagtcaacct
    42481 tggcgcaacg gcaatcggta ctggtctgaa cacgccgaaa gaatactctc cgctggcggt
    42541 gaaaaaactg gctgaagtca ctggtttcgc ctgtgttccg gctgaagatc tgattgaggc
    42601 gacatctgac tgtggcgcgt atgttatggt tcacagcgcg ctgaaacgtc tggcagtgaa
    42661 gatgtccaaa atctgtaacg acctgcgctt gctctcttct ggtcctcgtg ccggcctgaa
    42721 cgagatcaac ctgccggaac tgcaggcggg ctcttccatc atgccagcca aagtgaaccc
    42781 ggtagtaccg gaagtcgtaa accaggtatg ctttaaagtc atcggtaacg acaccaccgt
    42841 tacgatggcg gcggaagccg gtcagttgca gttgaacgtt atggagccgg ttatcggtca
    42901 ggcgatgttc gaatccatcc acattctgag caacgcgtgc tacaacctgc tggaaaaatg
    42961 cgttaacggc attaccgcga ataaagaagt gtgcgaaggg tacgtttata actccatcgg
    43021 tatcgtcact tacctcaacc cgttcatcgg ccaccacaac ggcgacatcg tcggtaaaat
    43081 ctgtgctgaa accggtaaga gcgtacgtga agttgtgcta gagcgcggcc tgttaacgga
    43141 agccgagctg gacgatattt tctccgtaca gaacttgatg cacccggctt ataaagctaa
    43201 acgttatact gatgaaagcg aacagtaatc gtacagggta gtaccaaaga ggcacgtcac
    43261 gatgacgtgc cttttttctt acaagaagtt accaaataac aacaatttaa tatcaacttg
    43321 ttaaacaaca aggaaggcta atatgatagt tgtcgaactt atcattgttt tgctggcaat
    43381 ctttttgggc gccagacttg ggggcatcgg tattggattc gcaggtgggc tgggtgttct
    43441 ggtacttgcc gccatcggcg tgaagccagg gacaattcca ttcgatgtca tttccatcat
    43501 catggcggtt atcgccgcga tctctgctat gcaggtcgcg ggcggtctgg attatttggt
    43561 aaaccagaca gaaaaactgc tgcgtaagaa cccgaaatac atcactatcc tcgcaccgat
    43621 tgtgacctat ttcctgacta tttttgctgg taccgggaac atttccctgg caacgctgcc
    43681 ggttattgct gaagtcgcga aggagcaggg aatcaaacct tgccgtccgc tctcaaccgc
    43741 cgtggtatcc gcgcagattg cgattaccgc ctcgccgatt tctgcggctg tggtgtatat
    43801 gtcttctgtt atggaaggtc atggcattag ctacattcac ctgctgtccg tggttatccc
    43861 ctctacgctg ctggcggtgc tggtgatgtc cttcctggtc acgatgctgt tcaactccaa
    43921 actgtcggac gacccgattt accgcaagcg tctggaagaa gggctgattg aactgcgtgg
    43981 tgaaaagcag attgaaatca aaccgatggc aaaaaattcc gtctggctgt tcctgctggg
    44041 cgttatctgc gtggttgttt atgcgattgt caacagtccg agcctcggcc tggttgagaa
    44101 accgctgatg aacaccacca acgctatttt gatcatcatg ttgagcgtcg caacgctgac
    44161 caccatcctg tgtaaagtgg aaactgacgc catcctcaac tccagtacct ttaaagcagg
    44221 gatgagcgcc tgtatttgta ttctgggcgt ggcgtggctg ggcgatacct tcgtatccgc
    44281 taacatcgac tggatcaaag acactgcggg tagcgtcatc caggggcatc cgtggctgct
    44341 ggccgtcatc ttcttctttg cttccgcgct gctctactct caggcggcaa cggcgaaagc
    44401 gctgatgccg atggcgctgg cgctgaacgt ctctccgctg acggcagtcg cttccttcgc
    44461 cgccgtttcc ggcctgttca ttttgccgac ctacccgact ctggttgcgg cggtacagat
    44521 ggatgacacc ggtacaaccc gtatcggtaa attcgtcttt aaccacccgt tcttcatccc
    44581 aggcaccctg ggcgtcgttc tggctatctg ctccggcttc ctgctgggca gctttatgct
    44641 gtaagtgttt cacccgcggg gcgtatcacg ccccgcattc tcccgccctt tgactaacat
    44701 cctgccctcg tccgttgtat agtgaccgtt cacttgcggg tctttttgtt ctttcgaggt
    44761 gtttatgctt gatgttaaga gtcaggatat ttccatcccc gaggctgttg tggtgctttg
    44821 taccgccccg gatgaagcta ccgcccagga tctggccgcc aaagtgctgg cggaaaaact
    44881 ggccgcctgc gccaccctcc tccccggcgc gacatcgctg tactactggg aaggcaaact
    44941 ggagcaggag tatgaagttc aaatgatctt aaaaaccacc gtttcacatc agcaagcgct
    45001 tatcgactgc ctgaagtctc atcacccgta tcaaacgcct gaacttctgg ttttacctgt
    45061 tactcacgga gatactgatt acctctcatg gctcaacgca tctttacgct gatcctgctg
    45121 ctgtgcagca catccgcctt cgccggatta ttcgacgcgc cgggtcgctc gcagttcgtc
    45181 cctgccgacc gggcgtttgt ttttgatttt cagcaaaatc aacacgatct taccctctcc
    45241 tggcaggtaa aagagggtta ctacctttac cgtaaacaaa tcagtatcac gccgacgaaa
    45301 gcggatatcg ccgcagtcca actcccggca ggcgtctggc atgaagatga attctacgga
    45361 aaaagcgaaa tctaccgtaa gcggctaaac gttccggtaa cggttaacca ggcggcggct
    45421 ggcgcgacat taacgataac gtaccagggg tgcgccgatg cgggattctg ttatccgccg
    45481 gaaacgaaaa cggtgccgct aagtgaagtc gccgcggcaa tagacgccac gccgacgcct
    45541 gctgtcaccc agacgggtga gacgtcaaaa cccgccgccc agctaccttt ttctgcgctc
    45601 tgggcgctac tgatcggcat aggcatcgcc tttacgccct gcgttttacc tatgtatccg
    45661 ctgatttccg gtattgtcct ggggggaagg caacgtttgt cgacggggcg cgcactgctg
    45721 ctggccttta tctatgtaca agggatggcg ctgacctata ccgcactggg tctggtcgtc
    45781 gccgcggcgg gattacagtt tcaggcggcg ctgcagcacc cttatgtgtt aatcggcctt
    45841 gccatcgtgt tcaccctgct tgcgttgtcg atgtttggcc tgttcacact acagctcccc
    45901 tcctcactgc aaacccggct gacattaatg agtaatcgtc agcaaggcgg ctcgcccggc
    45961 ggtgtttttg ttatgggggc gattgcagga ttaatttgct cgccctgtac cacagcgcca
    46021 ttaagcgcga tcctgcttta tatcgctcag agcggcaaca tgtggctggg cggcggtacg
    46081 ctgtatttgt atgcattagg tatgggtctg ccgctaatgc tggtcaccgt gtttggcaac
    46141 cgtctgctac cgaaaagcgg cccgtggatg gcgcatgtta aaaccgcttt tggtttcgtg
    46201 atcctcgcgt taccggtctt tttactggag cggattattg gcgaggcttg gggtttacgt
    46261 ctgtggtcgc tgctgggcgt cgctttcttt ggttgggcct ttatcaccag ccttcaggcc
    46321 agacgagcgt ggatgcgtat cgtacagatt atcctgctgg cggcagcgct cattagcgtg
    46381 cggcctctac aagattgggc attcggatcg ccatccgcgc aagctccagc gcacctcaat
    46441 ttcacggcta tttctaccgt ggatgaactc aatcaggcgc tggcgcaggc caaaggcaaa
    46501 cccgttatgc tggatttcta cgccgactgg tgcgtggcct gtaaagagtt tgaaaagtat
    46561 accttcagcg atccgagggt ccagcaggtg ctcggcgaca cggtgctctt gcaggctaac
    46621 gtcaccgcta acaatgcgca ggacgtcgcg ctgttaaagc atctgcaagt tctcgggctg
    46681 cccaccattc tgttctttga tgcccaaggc caggaacagc cgcaagcgcg agtcaccggc
    46741 tttatggacg ccgccacctt tagcgcgcat ttgcacgatc gccaaccatg agcgacactt
    46801 gcaaaagcaa agacggagga gaataccgtg caacgtgaag atattctggg agaagccctg
    46861 aaattactgg agacgcaagg gatagccgat actacgctgg aaatggtggc ggagcgcgta
    46921 aatcgcccac tcgacacatt acagcgtttc tggccagata aagaagccat tttatatgac
    46981 gcgctacgtt atctgagtca gcaggtagat atctggcgac gccagcttct tcttgatgag
    47041 acgttttctg ctgaacaaaa gctactggca cgctacagcg cgctttcgga atgtgtcagt
    47101 aataaccgtt atcctggttg cttgttcatt gccgcctgta cgttttatcc cgacccaacc
    47161 catcctattc accaactggc taatcaacaa aaacgcgcgg cacatgattt tacccatggg
    47221 ctactgacca cgctggaaat tgacgatccg gcgatggttg caaggcagat ggaactggtg
    47281 ctggaaggtt gtctcagccg aatgctggtc aaccgcagtc aggctgatgt agataccgct
    47341 cagcggttgg cggaagatat tctgcgtttt gcacagtgcc gtcagggtgg agcgctcacc
    47401 tgacgggtac tgattttatg cattttgcct gaaaagcagg cagtcagcgc gcttttatca
    47461 cttttttcgt gtaaagccgt tgacgaccgc gcccctttac ggtttaatgc gccccgttgc
    47521 ccggatagct cagtcggtag agcaggggat tgaaaatccc cgtgtccttg gttcgattcc
    47581 gagtccgggc accacctttc cttttttatg cttccctatg aattccaata tgtatgtaat
    47641 tcaataagtt agcgtaaaaa tctttccaga tgcgttttga tttatcccta cgtatccgga
    47701 aaattagggg tcaggttgag ggttcattca gttcgatgaa cggagaggcc ctcatgttga
    47761 ctgacagcaa gatccgcgcc gcgaaacccc tcgcaaaatc ctataaactc actgatgcac
    47821 aaggtctgta cctgacggta tccaccagtg gttcaaagct atggtatttc cgctaccgtt
    47881 ttgaaggtaa ggaaaatcgt ctggccttcg gcccctatcc gcaggttacg ctggcggaag
    47941 cccgcgaaaa gcgcgatgcg gcgcgtaagc tgctggtatc cggcgtttgc ccttctctgc
    48001 cccgcaaggc ggaaaaagcc gccgttgacg gtacgcgcac ctttcagtac atcgccacgg
    48061 cgtggcactc cagttgtctt aagctgtggt cagaagacca cgcggacaag atcctgacct
    48121 gcctgaagcg ctacgtcttc cccgatattg gcgcaatgga cattgcagag gttgaaaccc
    48181 gccatctggc gcagcttgtt aaatccatcg acgataaggg cgtgcatgac gttgccgggc
    48241 gggtgcgcca gcatctgacc aaaatcatgc gtcatgccgt acagcaggga acgattaaat
    48301 ataatccggc ttacgatctg gatggcgtcg tgacccctgt tgtgacccaa catcaccccg
    48361 ccctgcccct gaaacgcctg ccggagctgc tggacaagat taatggctac aaagggcggg
    48421 aactgacccg tctggcgctg gagttgaatc tgcacgtttt cctgcgctcc agtgagttac
    48481 gcctcgcccg ctgggatgag ttcaacctga aagctcgtat ctggacggtg ccagcaaagc
    48541 gggaagcggt gaagaacgtg cgtttctcag agcgtggcgc aaagatgaag gatgagcatc
    48601 tggtgccgct atctgcgcag gctgtcgccc tgctggagca gataaaggaa attaccggag
    48661 agtcggtatt tgtttttgcg ggtgctcact caatgaacaa gccgatgagt gaaaacacca
    48721 tcaacaaggc gctgcgcgtg attggttacg acaccaaaac cgaagtctgc ggtcacggat
    48781 tcagaacgat ggcctgtagc gccctgaacg aatccgcact gtggtctaag gacgccatcg
    48841 agcgccagat gagccacaag gagcgcaacg gcgtgcgggc ggcgtatgtg cataaggcgg
    48901 agcatctgga agcgcgtatg gagatgatgc agtggtggtc ggattatctc gacatgagcc
    48961 gcgaggggta cgtcgcgccg tatatttatg cgcggcggca taaggctgcc tgacccagcg
    49021 gcaatataat ttgttgataa tgaaaaagca gatcctgatt gaatccggat ctgc
//
LOCUS       DAJVBX010000011        43625 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.011, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000011 DAJVBX010000000
VERSION     DAJVBX010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 43625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43625
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.011"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            8..1243
                     /locus_tag="OPV72_000562"
     CDS             8..1243
                     /locus_tag="OPV72_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase"
                     /protein_id="HCR9912948.1"
                     /translation="MSVYKVPLEQNVLEAAQERITWTLETLPRVCVSFSGGKDSGLML
                     HLTATLARKMNKKIHVLFIDWEAQFSCTIAYIESLREYYADVIERFYWVALPLTTQNS
                     LSQYQPEWQCWQPGTDWVRQPPEDAITDPAFFSFYQHGMTFEQFVRDFADWFSEKRPA
                     AMLVGIRSDESYNRFVAIANSHKLRFADDKPWTTLAPKGHTWYIYPIYDWKTADIWTW
                     FAKTGKSCNPLYNLMYQAGVPVRYMRICEPFGPEQRQGLWLYHVIEPERWAAMYARVS
                     GVLSGGIYAGQDSHFYGHRKILKPDHLNWEEYALLLLHSMPEVTAEHYRNKIAVYLQW
                     YKKKGMNTIPQTQQGDIGSRDIPSWRRICKVLLNNDYWCRALSFSPTKPKSYQRYNER
                     MKAKRQEWGILCNTDSQPK"
     gene            1216..1833
                     /locus_tag="OPV72_000563"
     CDS             1216..1833
                     /locus_tag="OPV72_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HCR9912949.1"
                     /translation="MQHRLTTEITHFLSGLPEEERIAAINEFRRAIHNVSPFRDEPVD
                     CVLWVKNDHISPNDYNPNNVAPPEKKLLLKSIEKDGFTQPIVVVKANTEEYEIVDGFH
                     RHELGKGKAVLKRRLKGYLPVACLDRERHERMAATIRHNRARGRHQIHAMSEIVRELS
                     QLGWDESKIGQELGMDADEVLRLKQINGLQELFADRRFSRAWTVK"
     gene            complement(1834..2994)
                     /locus_tag="OPV72_000564"
     CDS             complement(1834..2994)
                     /locus_tag="OPV72_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCR9912950.1"
                     /translation="MRNNPLIPKSKLPNLGTTIFTQMSALAQKHQAINLSQGFPDFDG
                     PSYLHERLAYHVAQGANQYAPMTGAQALREAIADKTAEIYGYRPDDVSDITVTAGATE
                     ALYAAITALVRAGDEVICFDPSYDSYAPAVALSGGVLKRIALTPPHFRVDWQAFSALL
                     SERTRLVILNTPHNPTATVWRQADIEALWQAIGEREIYVLSDEVYEHICFAAEGHASV
                     LAHPQLRERAVAVSSFGKTFHMTGWKIGYCVAPAAISAEIRKVHQYLTFCVNTPAQLA
                     LADMLRAAPEHYRALPDFYRKKRDVLVNALAQSRLKVLPCEGTYFLLIDYSAVSTLND
                     VEFCQWLTEEVGVAAIPLSVFCAAPFPHQLIRLCFAKQESTLLAAAERLCKL"
     gene            3121..4209
                     /locus_tag="OPV72_000565"
     CDS             3121..4209
                     /locus_tag="OPV72_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HCR9912951.1"
                     /translation="MNHTEIRVVTGPANYFSHAGSLERLTDFFTPEQLSHAVWVYGER
                     AIAAARPYLPEAFERAGAKHLQFTGHCSERHVAQLAHACNDDRQVVIGVGGGALLDTA
                     KAHARRLALPFVAIPTIAATCAAWTPLSVWYNDAGQALQFEIFDDANFLVLVEPRIIL
                     QAPDDYLLAGIGDTLAKWYEAVVLAPQPETLPLTVRLGINSACAIRDLLLTSSEQALA
                     DKQQRRLTQAFCDVVDAIIAGGGMVGGLGERYTRVAAAHAVHNGLTVLPQTEKFLHGT
                     KVAYGILVQSALLGQDDVLAQLITAYRRFHLPTRLSELDVDIHNTAEIDRVIAHTLRP
                     VESIHYLPVTLTPDTLRAAFEKVEFFRI"
     gene            complement(4245..4442)
                     /locus_tag="OPV72_000566"
     CDS             complement(4245..4442)
                     /locus_tag="OPV72_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbdD/YjiX family protein"
                     /protein_id="HCR9912952.1"
                     /translation="MFDTLSKAGKYLGQAAKMMIGVPDYDNYVEHMRITHPDQTPMTY
                     EEFFRERQDARYGGKGGARCC"
     gene            complement(4506..6611)
                     /gene="cstA"
                     /locus_tag="OPV72_000567"
     CDS             complement(4506..6611)
                     /gene="cstA"
                     /locus_tag="OPV72_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein CstA"
                     /protein_id="HCR9912953.1"
                     /translation="MNKSGKYLVWTALSVLGAFALGYIALNRGEQINALWIVVASVCV
                     YLIAYRFYGLYIAKKVLAVDPTRMTPAVRHNDGLDYVPTDKKVLFGHHFAAIAGAGPL
                     VGPVLAAQMGYLPGMIWLLAGVVLAGAVQDFMVLFVSTRRDGRSLGELVKEEMGATAG
                     VIVLVACFMIMVIILAVLAMIVVKALTHSPWGTYTVAFTIPLAIFMGIYLRYLRPGRI
                     GEVSVIGLVFLIFAIISGGWVAASPTWAPYFDFTGVQLTWMLVGYGFVAAVLPVWLLL
                     APRDYLSTFLKIGTIVGLAVGILIMRPTLTMPALTKFVDGTGPVWTGDLFPFLFITIA
                     CGAVSGFHALISSGTTPKMLANEGQACFIGYGGMLMESFVAIMALVSACIIDPGVYFA
                     MNSPMAVLAPAGTADVVASAAQVVSSWGFAITPDTLHQIANEVGEQSIISRAGGAPTL
                     AVGMAYILHGALGGMMDVAFWYHFAILFEALFILTAVDAGTRAARFMLQDLLGVVSPG
                     LKRTDSLPANLLATALCVLAWGYFLHQGVVDPLGGINTLWPLFGIANQMLAGMALMLC
                     AVVLFKMKRQRYAWVALVPTAWLLICTLTAGWQKAFSPDAKIGFLAIANKFQAMIDSG
                     NIPPQYTESQLAQLVFNNRLDAGLTIFFMVVVVVLAVFSIKTALAALKIDKPTANETP
                     YEPMPENVDEIVTQAKGAH"
     gene            complement(6793..7206)
                     /gene="entH"
                     /locus_tag="OPV72_000568"
     CDS             complement(6793..7206)
                     /gene="entH"
                     /locus_tag="OPV72_000568"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proofreading thioesterase EntH"
                     /protein_id="HCR9912954.1"
                     /translation="MIWKRHLTLDELNATSQNTLVAHLGIVYTRLGDDVLEAEMPVDA
                     RTHQPFGLLHGGASAALAETLGSMAGYLMTRDGQCVVGTELNATHHRAVSQGKVRGVC
                     LPLHLGRQNQSWEITLFDEQGRRCCTCRLGTAVMG"
     gene            complement(7209..7964)
                     /gene="entA"
                     /locus_tag="OPV72_000569"
     CDS             complement(7209..7964)
                     /gene="entA"
                     /locus_tag="OPV72_000569"
                     /EC_number="1.3.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
                     EntA"
                     /protein_id="HCR9912955.1"
                     /translation="MASFDFSDKTVWVTGAGKGIGYATALAFVDAGARVIGFDREFTQ
                     ENYPFATEVMDVADAAQVAQVCQRVLQKTPRLDVLVNAAGILRMGATDALNVDDWQQT
                     FAVNVGGAFNLFSQTMAQFRRQQGGAIVTVASDAAHTPRIGMGAYGASKAALKSLALT
                     VGLELAGCGVRCNVVSPGSTDTDMQRTLWVSEDAEQQRIRGFGEQFKLGIPLGKIARP
                     QEIANTILFLASDLASHITLQDIVVDGGSTLGA"
     gene            complement(7964..8821)
                     /locus_tag="OPV72_000570"
     CDS             complement(7964..8821)
                     /locus_tag="OPV72_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase"
                     /protein_id="HCR9912956.1"
                     /translation="MAIPKLQSYALPTALDIPTNKVNWAFEPERAALLIHDMQDYFVS
                     FWGRNCPMMDQVIANIAALRQYCKEHHIPVYYTAQPKEQSDEDRALLNDMWGPGLTRS
                     PEQQKVVEALTPDEADTVLVKWRYSAFHRSPLEQMLKDTGRNQLIITGVYAHIGCMTT
                     ATDAFMRDIKPFMVADALADFSREEHLMALNYVAGRSGRVVMTESLLPTPIPASKAAL
                     RALILPLLDETDEPLDDENLIDYGLDSVRMMGLAARWRKVHGDIDFVMLAKNPTIDAW
                     WALLSRGVE"
     gene            complement(8835..10445)
                     /gene="entE"
                     /locus_tag="OPV72_000571"
     CDS             complement(8835..10445)
                     /gene="entE"
                     /locus_tag="OPV72_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2,3-dihydroxybenzoyl)adenylate synthase EntE"
                     /protein_id="HCR9912957.1"
                     /translation="MRIPFTRWPDEFARRYREKGYWQDVPLTDILTRHADSDKTAVIE
                     GERAFSYRQLNQAADNLACSLRRQGIKPGETALVQLGNVPELYITFFALLKLGVAPVL
                     ALFSHQRTELNAYAMQIAPTLVIADRQHTLFAGEDFLNRFVAEHRSARVVLLRNDDGD
                     HSLDAAMRQAAEGFTATPSPADEVAYFQLSGGTTGTPKLIPRTHNDYYYSVRRSNEIC
                     GFNEETRFLCAIPAAHNYAMSSPGALGVFLAKGTVVLATDPGATLCFPLIEKHQINAT
                     ALVPPAVSLWLQAIQEWGGNAPLASLRLLQVGGARLSATLAARIPAEIGCQLQQVFGM
                     AEGLVNYTRLDDSPERIINTQGRPMCPDDEVWVADADGNPLPPGEIGRLMTRGPYTFR
                     GYFNSPQHNVSAFDANGFYCSGDLISIDQDGYITVHGREKDQINRGGEKIAAEEIENL
                     LLRHPAVIHAALVSMEDELLGEKSCAYLVVKEPLRAVQVRRFLREQGVAEFKLPDRVE
                     CVASLPLTPVGKVDKKQLRQRLASRSPL"
     gene            complement(10455..11630)
                     /gene="entC"
                     /locus_tag="OPV72_000572"
     CDS             complement(10455..11630)
                     /gene="entC"
                     /locus_tag="OPV72_000572"
                     /EC_number="5.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismate synthase EntC"
                     /protein_id="HCR9912958.1"
                     /translation="MDMSLAEDAQETMATLAPDRFFFMSPYRSFTTSGCFARYTEPAV
                     AGDSPDSPFQQKLRQQFAEAKSQGIANPILVGAIPFDTRQPSSLFIPMAWQSFSRQQK
                     QRTARYFTDHQPLTVTARKAIPEQDAFEAMVARAAMLTATPDVDKVVLSRLIDITTDV
                     AVDSGALLERLVAQNPVSYNFHVPLADGGVLLGASPELLLRKEGERFSSLPLAGSARR
                     QPDDVLDREAGNRLLASQKDRHEHELVTQAMKQILRDRSTELQLPSSPQLITTPTLWH
                     LGTPFEGKANAGENALTLACLLHPTPALSGFPHQVAKKLIAELEPFDRELFGGIVGWC
                     DAEGNGEWVVTIRCAKLHGNQVRLFAGAGIVPASSPVGEWRETGVKLSTMLNVFGLH"
     gene            11938..12894
                     /gene="fepB"
                     /locus_tag="OPV72_000573"
     CDS             11938..12894
                     /gene="fepB"
                     /locus_tag="OPV72_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe2+-enterobactin ABC transporter
                     substrate-binding protein"
                     /protein_id="HCR9912959.1"
                     /translation="MRLSAFYRWLLLVVGLSISGISLAQDAGWPRQIQDSRGVHTLDH
                     KPARIVSTSVTLTGSLLAIDAPVVASGATTPNNRFADDQGFMRQWSDVAKARHVARLY
                     IGEPNAETVAAQMPDLILISATGGDSALALYDQLSAIAPTLVINYDDKSWQSLLTQLG
                     EITGQEKQAAARIAEFEAQLTTVKQRIALPPQPVSALVYTPAAHSANLWTPESAQGKL
                     LTQLGFTLATLPQGLQTSKSQGKRHDIIQLGGENLAAGLNGESLFLFAGDNNDVAALY
                     ANPLLAHLPAVQNKRVYALGTETFRLDYYSATLLLNRLAALF"
     gene            complement(12957..14201)
                     /gene="entS"
                     /locus_tag="OPV72_000574"
     CDS             complement(12957..14201)
                     /gene="entS"
                     /locus_tag="OPV72_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin transporter EntS"
                     /protein_id="HCR9912960.1"
                     /translation="MNRQSWLLNLSLLKTHPAFRAVFLARFISIVSLGLLGVAVPVQI
                     QMMTHSTWQVGLSVTLTGGAMFIGLMVGGVLADRYERKKVILLARGTCGIGFIGLCVN
                     ALLPEPSLLAIYLLGLWDGFFASLGVTALLAATPALVGRENLMQAGAITMLTVRLGSV
                     ISPMLGGILLASGGVAWNYGLAAAGTFITLLPLLTLPRLPVPPQPRENPFIALLAAFR
                     FLLASPLIGGIALLGGLVTMASAVRVLYPALAMSWQMSAAQIGLLYAAIPLGAAIGAL
                     TSGQLAHSVRPGLIMLVSTVGSFLAVGLFAIMPIWIAGVICLALFGWLSAISSLLQYT
                     LLQTQTPENMLGRMNGLWTAQNVTGDAIGAALLGGLGAMMTPVASASVSGFGLVIIGL
                     LLLLVLGELRRFRQTPPVSDAG"
     gene            14312..15319
                     /gene="fepD"
                     /locus_tag="OPV72_000575"
     CDS             14312..15319
                     /gene="fepD"
                     /locus_tag="OPV72_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+)-siderophore ABC transporter permease"
                     /protein_id="HCR9912961.1"
                     /translation="MSCSFSVTRAFAVPGLLLLLSLAAVLSLVIGAKPLPAAVVLEAF
                     TGVCQSADCTIVLDARLPRTLAGLLAGGALGLAGALMQTLTRNPLADPGILGVNNGAS
                     FAIVLGAALFGFSTPLEQLFMAFSGALIASLIVAFTGSQGGGQLSPVRLTLAGVALGA
                     VLEGLTSGIALLNPEVYDQLRFWQAGSLDIRSLQTLKVALAPVVIAGIVALFLSRALN
                     SLSLGSDTATALGSKVARTQLIGLLAITVLCGSATALVGPIAFIGLMMPHMARWLVGA
                     DHRWSLPVTLLATPALLLFADIIGRLLVPGELRVSVVSAFIGAPVLIFLVRRKSSGGG
                     L"
     gene            15319..16308
                     /gene="fepG"
                     /locus_tag="OPV72_000576"
     CDS             15319..16308
                     /gene="fepG"
                     /locus_tag="OPV72_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-enterobactin ABC transporter permease"
                     /protein_id="HCR9912962.1"
                     /translation="MFLSRRLIVSCLLLAAGCFAIGLWSLQSGAVPLETGQIIAALLG
                     DAPRNITLVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSG
                     VLVAMVLFGQHLTAIALAAMAGGIVTSLIVWLLAWRNGIETFRLIIIGIGIRAMLVAF
                     NTWLLLQASLETALTAGLWNAGSLNGLTWAKTWPSAPLIMVMLTGAALLVRRMRLLEM
                     GDDSACALGVSVERSRLMLMLVAVSLTAAATALAGPISFIALVAPHIARRLSGTARWG
                     LTQSALCGALLLLAADACAQQLFMPYQLPVGVVTVSLGGIYLIVLLIQESRKK"
     gene            16305..17099
                     /gene="fepC"
                     /locus_tag="OPV72_000577"
     CDS             16305..17099
                     /gene="fepC"
                     /locus_tag="OPV72_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-enterobactin ABC transporter ATP-binding
                     protein"
                     /protein_id="HCR9912963.1"
                     /translation="MTESVARLRGDQLTLGYGSYTVAKNLNVSIPDGHFTAIIGPNGC
                     GKSTLLRTLSRLMTPVDGHVWLDGEQIQRYASKEVARRIGLLAQNATTPGDITVQELV
                     ARGRYPHQPLFTRWRKEDADAVASAMRATGITSLAAQSVDTLSGGQRQRAWIAMVLAQ
                     ETSIMLLDEPTTWLDISHQIDLLELLSDLNREKGYTLAAVLHDLNQACRYATHLIALR
                     EGNIVAQGAPKEIVTAELIEKIYGLRCMIIDDPVAGTPLVVPLGRR"
     gene            complement(17152..18288)
                     /gene="fepE"
                     /locus_tag="OPV72_000578"
                     /pseudo
     CDS             complement(17152..18288)
                     /gene="fepE"
                     /locus_tag="OPV72_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459581.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPS O-antigen length regulator"
     gene            complement(18538..22422)
                     /gene="entF"
                     /locus_tag="OPV72_000579"
     CDS             complement(18538..22422)
                     /gene="entF"
                     /locus_tag="OPV72_000579"
                     /EC_number="6.3.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin non-ribosomal peptide synthetase
                     EntF"
                     /protein_id="HCR9912964.1"
                     /translation="MTQRLPLVAAQPGIWMAEKLSDLPSAWSVAHYVELNGELDAPLL
                     AKAVAVGMQQADTLRMRFTEENGEVWQWIDPEHTFGEPPIADLRDQPDPHLAALALMQ
                     ADLRQNLRADSGKPLAFHQLIRIDDTRWYWYQRYHHLLVDGFSFPAITRQIAAIYRAW
                     QSDAPTPESPFTPFVDVVEEYQRYRQSEAWQRDGAFWAQQRRELPPPASMSAAPLPGR
                     SASADILRMKLSAPAGAFRQLAAHMPEIPRADLALALVTLWLGRLCGRMDYAAGFIFM
                     RRMGSAALTATGPVLNVLPLAVNLHATEDLPTLAKRLAAQLKKMRRHQRYDAEQIVRD
                     SGRAAGETPLFGPVLNIKVFDYHLDFPGIQAQTHTLATGPVNDLELALFPDENGGLDI
                     ELLANAQRYDDATLSRHALRLMALITQFADNPALRCGDAQMLLAEEQTQLTHLNNTAV
                     TIPAATLSDLVAQQAQKTPEASALADAHYHFTYREMREQVVALAYALRERGVQPGDSV
                     AVALPRSVFLTLALHGIVEAGAAWLPLDTGYPDDRLRMMLEDAQPKLLITTQAQLARF
                     HDIPGMEYLCYSQPLPVSDATPLGLSLPHHTAYIIFTSGSTGRPKGVMVGQTAIVNRL
                     LWMQDHYPLTADDVVAQKTPCSFDVSVWEFFWPFIAGAKLVMAEPEAHRDPLAMQRFF
                     AQYGVTTTHFVPSMLAAFIASLTPASAGKSCASLKRVFCSGEALPTALCREWETLTNA
                     PLHNLYGPTEAAVDVSWYPACGDELAAVDGNSIPIGYPVWNTGLRILDAHMQPVPPGV
                     AGDLYLTGIQLAQGYLGRPDLTASRFIADPFAPGERMYRTGDVARWLDSGVVEYLGRS
                     DDQLKIRGQRIELGEIDRVMQTLPDVEQAVAHACVFNQAAATGGDARQLVGYLVSHSG
                     LPLDLPALQDKLRQKLPAHMVPVVLLQLASLPLSANGKLDRKALPLPDLTPRVKGRAP
                     QSATEIAVAAAFSRLLGCEINDVESDFFALGGHSLLAMKLAAQLSQTFNRQVTPGQVM
                     VASDVAQLSKLLDTDDDERSRNLGFGPLLPLRESDGPTLFCFHPASGFAWQFSVLSRY
                     LSPSWSIMGIQSPRPVGPMQIATTLDEVCEHHLATLLARQPHGPYYLLGYSLGGTLAQ
                     GIAARLRARGETVAFLGLLDTWPPETQNWRGKEANGLNPDVLAEIERERAAFVAAQQG
                     NASDALFTAIEGNYADAVRLLTTAHSAPFDGHATLFVADKTVPEDVSPEQSWSPWIAS
                     LAIYRQPCAHVDIISPSAFETIGPIISELINK"
     gene            complement(22419..22637)
                     /locus_tag="OPV72_000580"
     CDS             complement(22419..22637)
                     /locus_tag="OPV72_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MbtH family protein"
                     /protein_id="HCR9912965.1"
                     /translation="MEFSNPFDNPQGQFYILQNAQRQFSLWPAACALPAGWGVVCEPQ
                     SQDACQQWLNTRWTTLNPAHYADKQEAK"
     gene            complement(22668..23882)
                     /gene="fes"
                     /locus_tag="OPV72_000581"
     CDS             complement(22668..23882)
                     /gene="fes"
                     /locus_tag="OPV72_000581"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterochelin esterase"
                     /protein_id="HCR9912966.1"
                     /translation="MKEALATGSEAWWRTKTGPEWIREKDGNYRVTFWWRDPQGNETH
                     SPIRRVWVYITGVTDHHQNAQPQTMARIAGTDVWRWSTALSANWRGSYCFIPTERDDV
                     FAAFAPGETPDRNALREGWRQLLPQAIADPLNSQSWRGGRGHAVSALEMPDAPRQPGW
                     DRPETSYSPPLMMQWHSERLGNSRRVWILTTGDEATEERPLAILLDGQFWAENMPVWP
                     ALASLTHQRLLPGAVYLLIDAIDTQHRNQELPCNADFWLAVQQELLPQVRAVTPFSDD
                     AGRTVVAGQSFGGLSALYAGLNWPTRFGCVLSQSGSFWWPHRITPPEGEVITRLKTGA
                     LCARGLRIVLEAGVREPIVFQANQALYAQLNTSQQSIFWRQVDGGHDALCWRGGLTQG
                     LMLLWQPLIDTL"
     gene            24071..26326
                     /locus_tag="OPV72_000582"
     CDS             24071..26326
                     /locus_tag="OPV72_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent siderophore receptor"
                     /protein_id="HCR9912967.1"
                     /translation="MNKKIHSLTLLVNLGIYGAALPVMAEEKTDSAALTNEDTIVVTA
                     AQQNLQAPGVSTITADEIRKNPPARDVSEIIRTMPGVNLTGNSTSGQRGNNRQIDIRG
                     MGPENTLILIDGKPVTSRNSVRLGWRGERDTRGDTAWVPPEMIERIEVLRGPAAARYG
                     NGAAGGVVNIITKKGGSEWHGSWNTYFNAPEHKDEGATKRTNFSLNGPLGGDFSFRLY
                     GNLDKTQADARNINQGHQSERTGSYADTLPAGREGVINKDINGVVRWDFAPLQSLELE
                     AGYSRQGNLYAGDTQNTNTNQLVKDNYGKETNRLYRQNYSLTWNGGWDNGVTTSNWVQ
                     YEHTRNSRMPEGLAGGTEGIFDPKASQKYADADLNDVTLHSEVSLPFDLLVNQNLTLG
                     TEWAQQRMKDQLSNSQTFMGGNIPGYSSTNRSPYSKAEIFSLFAENNMELTDSTMLTP
                     GIRFDHHSIVGDNWSPSLNLSQGLGDDFTLKMGIARAYKAPSLYQTNPNYILYSKGQG
                     CYATGAGTGIGCYMMGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRNKIEAGT
                     VPLQRINNGKTDVYQWENVPKAVVEGLEGTLNVPVSDTVNWTNNVTYMLQSKNKETGE
                     RLSIIPQYTLNSTLSWQVRQDVSLQSTFTWYGKQEPKKYDYQGNPVTGTDKQAVSPYS
                     IVGLSATWDVTKNVSLTGGVDNLFDKRLWREGNAQTVRDTQTGAYMAGAGAYTYNEPG
                     RTWYMSINTHF"
     gene            26373..27077
                     /gene="entD"
                     /locus_tag="OPV72_000583"
     CDS             26373..27077
                     /gene="entD"
                     /locus_tag="OPV72_000583"
                     /EC_number="6.3.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin synthase subunit EntD"
                     /protein_id="HCR9912968.1"
                     /translation="MLTSHFPLPFAGHRLHIVDFDASSFHEHDLLWLPHHDRLRSAGR
                     KRKAEHLAGRIAAVHALREVGVRAVPGIGDKRQPLWPDGLFGSISHCASTALAVISRQ
                     RVGVDIEKIMSQHTATELAPSIIDSDERQILQASSLPFPLALTLAFSAKESVYKAFSD
                     RVTLPGFDSAKITSLNATHISLHLLPAFAAMMAERTVRTEWFQRGNSVITLVSAITRF
                     PHDRSAPASILSAIPR"
     gene            27089..28207
                     /locus_tag="OPV72_000584"
     CDS             27089..28207
                     /locus_tag="OPV72_000584"
                     /EC_number="6.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--cysteine ligase"
                     /protein_id="HCR9912969.1"
                     /translation="MALNDFHVSEPYTLGIELEMQVINPPGYDLSQDSSTLIDAVKPQ
                     LTAGEIKHDITESMLEMATGVCRDIDQVAAQLSAMQHVILQAASEHHLGICGGGTHPF
                     QKWQRQEVCDNERYQRTLENFGYLIQQATVFGQHVHVGCANGDDAIYLLHGLSHFVPH
                     FIALSAASPYMQGSDTRFACARLNIFSAFPDNGPMPWVSNWQEFAGLFRRLSYTTMID
                     SIKDLHWDIRPSPAFGTVEVRVMDTPLTLDHAINMAGLIQATAHWLLTERPFKPQEQD
                     YLLYKFNRFQACRYGLEGVLTDVYTGDRRRLADDTLRLLDNVTPSARKLGADSAIDAL
                     RLQVKKGGNEAQYMREFIADGGSLIGLVQKHCEIWAGQ"
     gene            28274..28522
                     /locus_tag="OPV72_000585"
     CDS             28274..28522
                     /locus_tag="OPV72_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1158 family protein"
                     /protein_id="HCR9912970.1"
                     /translation="MKHPLESLMTAAGILLMALLSSLLLPAPSLGLALAQKLVGIFHL
                     MDLNQLYTLLFCLWFLLLGTLEYYVIRFIWRRWFSLAD"
     gene            complement(28528..28869)
                     /locus_tag="OPV72_000586"
     CDS             complement(28528..28869)
                     /locus_tag="OPV72_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RamA family antibiotic efflux transcriptional
                     regulator"
                     /protein_id="HCR9912971.1"
                     /translation="MTISAQVIDTIVEWIDDNLNQPLRIDDIARHAGYSKWHLQRLFM
                     QYKGESLRRYVRERKLKLAARDLRDTDQKVYDICLKYGFDSQQTFTRIFTRTFNLPPG
                     AYRKEKHGRTH"
     gene            29158..29739
                     /locus_tag="OPV72_000587"
     CDS             29158..29739
                     /locus_tag="OPV72_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCR9912972.1"
                     /translation="MARPKSEDKKQALLEAATQAIAQSGIAASTAVIARNAGIAEGTL
                     FRYFATKDELINTLYLHLKQNLCQSMIMELDRSITDAKTMTRFIWNSYISWGLNHPAR
                     HRAIRQLAVSEKITKETEQRADDMFPELRDLCHRSVLMVFMSDEYRAFGDGLFLALAE
                     TTMDFAARDPARAGEYIALGFEAMWRALTREEQ"
     gene            29739..30107
                     /locus_tag="OPV72_000588"
     CDS             29739..30107
                     /locus_tag="OPV72_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HCR9912973.1"
                     /translation="MDGQTLHACAKRFALELPFTEHCWPFGPQYDVFKVGGKIFMLFT
                     EHHCRPVVNLKSAPQKSLVNQQIYPSIAPGYHMNKKHWISVYAGEDITVSLLNDLIND
                     SWNLVVDGLPKREQLRLRPR"
     gene            30204..30857
                     /gene="nfsB"
                     /locus_tag="OPV72_000589"
     CDS             30204..30857
                     /gene="nfsB"
                     /locus_tag="OPV72_000589"
                     /EC_number="1.5.1.34"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-insensitive NAD(P)H nitroreductase"
                     /protein_id="HCR9912974.1"
                     /translation="MDIVSVALKRYSTKAFDPSKKLTAEEADKVKTLLQYSPSSTNSQ
                     PWHFIVASTEEGKARVAKSAAGNYTFNERKMLDASHVVVFCAKTAMDDAWLQRVVDQE
                     DADGRFATPEAKAANDKGRRFFADMHRVSLKDDHQWMAKQVYLNVGNFLLGVAAMGLD
                     AVPIEGFDAEVLDAEFGLKEKGYTSLVVVPVGHHSIEDFNAGLPKSRLPLETTLTEV"
     gene            31057..31182
                     /locus_tag="OPV72_000590"
                     /pseudo
     CDS             31057..31182
                     /locus_tag="OPV72_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459569.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
     gene            complement(31212..33182)
                     /locus_tag="OPV72_000591"
     CDS             complement(31212..33182)
                     /locus_tag="OPV72_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter domain-containing protein"
                     /protein_id="HCR9912975.1"
                     /translation="MTQKRTLLKYGILSLALAAPLSACAFDSLTVIGDSLSDTGNNGR
                     WTWDSGQNKLYDEQLAERYGLALSPSSNGGSNYAAGGAMTAPELNPQDNTADQVRQWL
                     ANTGGKADHNGLYIHWVGGNDLAAAIARPAMAQQIAGNSATSAAAQVGLLLDAGAGLV
                     VVPNVPDISATPELLEAVITAGLGAAAPPALKAALEALAEGATPDFASRQQAIRKALL
                     AAAATVSSNPFIQQLLVEQLLAGYEKVAEQASALTDYYNQMEEKGLEQHGGNIARADI
                     NGLFKEILANPQAFGLTNTVGMACPPGVSASVCSSAMPGFNASQDYLFADHLHPGPQV
                     HTIIAQYIQSIIAAPVQATYLNQSVQSMAQGSRTTLDSRYQQLRQGENPVGSLGMFGG
                     YSGGYQRYDNNEADGNGNHNNLTVGVDYQLNEQVLLGGLIAGSLDKQHPDDNYRYDAR
                     GFQAAVFSHLRAGQAWLDGDLHYLSAKFSNIQRSITLGALRRVEEGETNGRLWGARLT
                     SGYDFVMMPWLTTGPMLQYAWDYSHVNGYSEKLNTSTSMRFGDQNAHSQMGSVGWRLD
                     LRHSIIHSWAQINYRRQFGDDTYVANGGLKSTALTFSRAGKAQDKNWVDIAIGADFPL
                     SATVSAFAGLAQTAGLSDGNQTRYNVGFSARF"
     gene            33493..34740
                     /locus_tag="OPV72_000592"
     CDS             33493..34740
                     /locus_tag="OPV72_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HCR9912976.1"
                     /translation="MQELISQVEDLAGIEMNHTTSLVVIFGIIFLTAVVVHIILHWIV
                     LRAFEKRASASSRLWLQIITQNKLFHRLAFTLQSIIVNIQAALWLQKGSEAADILTTC
                     AQLWIMTYALLSLFSLLDVIFNLSQKWPAASQLPLKGIFQGIKLIGAIIVGILMISLL
                     IGQSPAILISGLGAMAAVLMLVFKDPILGLVAGIQLSANDMLKLGDWLEMPKYGADGA
                     VIDIGLTTVKVRNWDNTITTIPTWSLVSDSFKNWSGMSASGGRRIKRSINIDATSIHF
                     LDDDEKQRLLTAQLLKPYLTSRHQEIDEWNKQLDAPESALNHRRMTNIGTFRAYLNEY
                     LRHHPRIRKDMTLMVRQLAPDDHGLPIEIYAFTNTVVWLEYESIQADIFDHIFAVVEE
                     FGLRIHQTPTGSDIRALSGTLRH"
     gene            complement(34782..36176)
                     /gene="pheP"
                     /locus_tag="OPV72_000593"
     CDS             complement(34782..36176)
                     /gene="pheP"
                     /locus_tag="OPV72_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine transporter"
                     /protein_id="HCR9912977.1"
                     /translation="MKNASTASGASVSDAASKNEPTLQRGLQNRHIQLIALGGAIGTG
                     LFLGIGPAIQMAGPAVLLGYGVAGIIAFLIMRQLGEMVVEEPVSGSFAHFAWKYWGPF
                     AGFLSGWNYWVMFVLVGMAELTAAGIYMQYWLPDVPTWVWAAVFFIIINAVNLVNVRL
                     YGETEFWFALIKVLAIIGMIGFGLWLLFSGHGGEHASIDNLWRYNGFFATGWHGLLLS
                     LAVIMFSFGGLELIGITAAEARDPQKSIPKAVNQVVYRILLFYIGSLVVLLALYPWVE
                     VKSNSSPFVMIFHNLDSNVVASALNFVILVASLSVYNSGVYSNSRMLFGLSVQGNAPK
                     FLTRVSHRGVPVNSLMLSGAITSLVVLINYLLPQKAFSLLMALVVATLLLNWIMICLA
                     HLRFRAAMRRKGRETQFKALFYPAGNYLCIAFLALILVLMCTMDDMRLSAILLPVWIV
                     FLFIAFTVLRRKAH"
     gene            36502..37677
                     /locus_tag="OPV72_000594"
                     /pseudo
     CDS             36502..37677
                     /locus_tag="OPV72_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459559.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein"
     gene            complement(37756..38316)
                     /locus_tag="OPV72_000595"
     CDS             complement(37756..38316)
                     /locus_tag="OPV72_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgB family protein"
                     /protein_id="HCR9912978.1"
                     /translation="MDKYLRLLSQGDRLGLTLIRLSIAIVFIWIGLLKFVPYEADSIT
                     PFVANSPFMSFFYEHPEEYRQHLTHEGELKPEERAWQTANNTYAFSDGLGVVELIIAA
                     LVLANPVSRWLGLAGGVLAFLTPFVTLSFLITTPEAWVMPLGDAHYGFPYLSGAGRLV
                     LKDTLMLAGAVMIMADSARSLLLQRQ"
     gene            complement(38329..38565)
                     /locus_tag="OPV72_000596"
     CDS             complement(38329..38565)
                     /locus_tag="OPV72_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HCR9912979.1"
                     /translation="MLKVTTLIASLLAAPLAFSASAQPLTDVEYISVSAVSATPSMLE
                     DAIARLAQSKQASSWKITSMRIDNTGYATAILYK"
     gene            complement(38722..40047)
                     /locus_tag="OPV72_000597"
     CDS             complement(38722..40047)
                     /locus_tag="OPV72_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridine nucleotide-disulfide oxidoreductase"
                     /protein_id="HCR9912980.1"
                     /translation="MTQYQALIIGFGKAGKTLAATLAKTGWRVAIIEQSASMFGGTCI
                     NIGCIPTKTLVYDAEREGDFSVAMQRKAAVVNFLRDKNFHNLADLDNVDVIEGRAEFI
                     DNHTLRVFQADGERVLRGEKIFINTGAESVIPAITGLTTTAGVFDSTGLLSLSQRPAR
                     LGILGGGYIGLEFASMFANFGTKVTIFEAAPQFLPREDRDIAQAITHILQEKGVELIL
                     NANVQAVSSTEGAVQVETPEGAHLVDALLVASGRKPATAGLQLQNAGVAVNERGGIIV
                     DDYLRTTADNIWAMGDVTGGLQFTYISLDDFRIVRDGLLGDGKRSTRDRQNVPYSVFM
                     TPPLSRVGLTEEQARASGATVQVVTLPVAAIPRARVMNDTRGVLKAVVDVNTQRIVGV
                     SLLCVDSHEMINIVKTVMDADLPYTVLRDQIFTHPTMSESLNDLFSLIK"
     gene            40263..41117
                     /locus_tag="OPV72_000598"
     CDS             40263..41117
                     /locus_tag="OPV72_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCR9912981.1"
                     /translation="MDALSRLLTLNAPQGSIDKNCPLGGDWQLPHAAGELSVIRWHTV
                     TQGEAQLEMPTGDAMTLTPGKVVILPQNSAHRLRQSGEAPTHIVCGSLRLHTTSRYFL
                     TALPEVLCLAPPPHSPASIWLNAAISLLQQESERHLPGADVLYSQQCATLFTLAIRDW
                     LSQAGTAKSVLNLLLHPRLGRVILHMLETPAHPWTVETLVQRVHMSRASFAQLFRDVS
                     ATTPLAVLTTLRLQIAAQTLSREALPVMVIAESVGYASESSFHKAFVREFGCTPGEYR
                     KRVNALGR"
     gene            complement(41168..41380)
                     /locus_tag="OPV72_000599"
     CDS             complement(41168..41380)
                     /locus_tag="OPV72_000599"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9912982.1"
                     /translation="MPGLYRGLPLYAGGREQRDKNDRKGAGSEVMSRIATPMIGGMIT
                     APLLSLFIIPAAYKLMWLRRHRRLAA"
     gene            41284..41479
                     /locus_tag="OPV72_000600"
                     /pseudo
     CDS             41284..41479
                     /locus_tag="OPV72_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000635961.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
     gene            41611..41922
                     /locus_tag="OPV72_000601"
     CDS             41611..41922
                     /locus_tag="OPV72_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-binding protein"
                     /protein_id="HCR9912983.1"
                     /translation="MNKFTSLLAVVFISAGVHTAEKMESRQLSATAHEMMNNGDAFAH
                     QQMAQTQKPSAPTTVENATPFSEMDDYEKAMVIHQSMNNAHSFSHEIQAEEHHKQIKR
                     N"
     gene            42325..42687
                     /locus_tag="OPV72_000602"
     CDS             42325..42687
                     /locus_tag="OPV72_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HCR9912984.1"
                     /translation="MLKLFAKYTSIGVLNTLIHWGVFAFCVYGMHTHQALANFSGFVI
                     AVSFSFYANARFTFNASTTTLRYMMYVGFMGTLSAVVGWMADKCSLPPLLTLVTFSAI
                     SLICGFIYSKFIVFRDAK"
     gene            42684..43610
                     /locus_tag="OPV72_000603"
     CDS             42684..43610
                     /locus_tag="OPV72_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCR9912985.1"
                     /translation="MKISLVVPVFNEEATIPIFYKTVREFEELKPYEVEIVFINDGSK
                     DATESIINKIAASDPLVIPLSFTRNFGKEPALFAGLDHATGDAVIPIDVDLQDPIEVI
                     PHLIEKWQAGADMVLAKRSDRSTDGRMKRKTAEWFYKLHNKISNPKIEENVGDFRLMS
                     RDVVENIKQMPERNLFMKGVLSWVGGKTDVVGYARAERVAGDSKFNGWKLWNLALEGI
                     TSFSTFPLRIWTYIGLFIAGMSFLYGTWMIIDKLIFGNNVPGYPSLLVSVLFLGGVQL
                     IGIGILGEYIGRIYIETKKRPKYIIKNGKKNG"
BASE COUNT        10401 a        12366 c        11204 g         9654 t
ORIGIN      
        1 tccagagatg tcggtttata aagttccgct tgagcaaaat gttctggaag cggctcaaga
       61 gcgtataaca tggaccctgg aaactttacc ccgggtctgc gtctcatttt ctggtggtaa
      121 agattcagga cttatgctgc acctgacggc aacgttggcg cgcaaaatga ataaaaagat
      181 ccacgttctt ttcattgact gggaagcgca attctcctgt actatcgctt atattgaatc
      241 gttacgtgaa tactacgcgg acgttattga gcgtttttat tgggtcgcat tacccttaac
      301 cacacaaaat tccctttcac aataccagcc ggagtggcag tgttggcagc cgggaaccga
      361 ctgggtacga caaccgccag aagatgcgat taccgatccg gccttttttt ccttttatca
      421 acacggcatg acttttgaac agttcgttcg cgattttgcc gactggtttt cagaaaagcg
      481 ccctgccgct atgctggtcg gtattcgttc cgacgaatcc tataaccggt ttgtcgctat
      541 cgctaactcg cataagctgc gctttgccga cgataagccc tggaccacgt tggcccccaa
      601 ggggcacacc tggtatatct accccatcta tgactggaaa accgcagata tctggacctg
      661 gttcgccaaa acaggtaaat catgtaaccc cttgtataat ttgatgtatc aggctggcgt
      721 accggtccgt tacatgcgta tttgcgaacc attcggcccg gaacaacggc aggggttatg
      781 gctgtatcat gttatcgaac ctgagcgctg ggcggccatg tacgccagag tcagcggcgt
      841 actcagcgga ggaatatacg ccgggcagga cagccatttt tacggccacc ggaaaatttt
      901 aaaacccgat caccttaact gggaggagta cgcgctgctc ctgctacaca gtatgcctga
      961 agtcactgcc gaacattacc gtaataaaat cgccgtttat ttgcagtggt ataagaaaaa
     1021 aggcatgaac accattccac agacgcagca gggcgatatc ggatcgcggg atattccgtc
     1081 atggcgacgg atctgcaaag tattactgaa caatgattac tggtgccggg cgctgtcatt
     1141 cagtccgaca aaacctaaga gttaccagcg ttataacgaa cgcatgaaag ctaaacgcca
     1201 ggaatggggg atcttatgca acaccgactc acaaccgaaa taactcactt tctctctgga
     1261 ctgcctgaag aggaaaggat cgccgccatt aatgaattta gaagggcgat acataacgtt
     1321 agtccttttc gcgatgagcc agtcgattgt gtcctgtggg tgaaaaacga tcatatttcg
     1381 cctaatgact acaacccgaa taacgttgcg ccaccggaga aaaaattgct gcttaaatcg
     1441 attgaaaaag atggctttac tcagccgatt gtggtggtaa aggccaatac ggaggaatac
     1501 gagattgtag acggctttca ccgtcatgag ttgggcaaag gaaaagcggt cctgaaaagg
     1561 cgcctgaaag gttatctgcc ggtagcgtgt ctggacagag aacgtcacga acggatggcg
     1621 gcaaccatcc ggcataaccg cgcgcgcgga cgccaccaga tccacgccat gtccgaaatc
     1681 gtacgcgaac tttctcagct aggctgggac gagagcaaaa tcggacagga gttaggtatg
     1741 gacgccgatg aagtcctgcg cctgaaacag atcaacggac tgcaggaact ctttgcagac
     1801 cgtcgattct ccagagcgtg gacggttaaa taactacagt ttacacaggc gctctgcggc
     1861 ggccagcagc gttgattcct gtttagcgaa acataaacgt ataagctgat gcgggaaagg
     1921 ggcggcgcaa aagacagaga gcggaatagc ggcgacaccg acttcttcgg ttagccactg
     1981 acaaaactca acgtcattta gcgtcgacac tgcgctgtaa tcgattaaca aaaaataggt
     2041 accttcacag ggcagcactt ttaatcggct ttgcgccagc gcgttaacca gcacatcgcg
     2101 ttttttccgg taaaaatcgg gtaacgcgcg atagtgttcc ggcgcggcgc gcagcatatc
     2161 cgccagcgcc agttgcgccg gcgtattgac gcaaaacgtc aggtactggt gaactttgcg
     2221 tatttcggcg ctaatggccg caggcgcaac gcagtaacca atcttccatc ccgtcatatg
     2281 aaaggtttta ccaaacgatg aaacggcaac cgcccgctct cgtaactgag ggtgcgccag
     2341 tacgctggca tgaccttcgg cggcaaaaca aatatgctcg tacacttcat cgcttaatac
     2401 ataaatttcc cgctcgccga tagcctgcca cagcgcctcg atatccgcct gacgccagac
     2461 ggtagcggtg ggattatgcg gcgtattgag gatcaccagc cgcgtgcgct cgctaagcaa
     2521 cgccgaaaac gcctgccagt cgacgcgaaa atgcggcggc gtaagcgcta tgcgttttaa
     2581 cacgccgccg gaaagcgcca cggccggggc atagctgtcg taactgggat cgaaacagat
     2641 aacctcatcc cctgcccgca ccagcgcggt aatcgccgca tacagcgctt ctgtcgcgcc
     2701 cgccgtgacg gtgatatcac ttacgtcatc gggtcgataa ccatatattt ccgccgtttt
     2761 atcggctatg gcctcccgca gcgcctgcgc gcccgtcatc ggcgcatatt gattcgcgcc
     2821 ctgcgcgaca tgataagcca accgctcgtg caaataagaa ggaccatcaa aatcagggaa
     2881 gccttgcgat aaatttattg cctgatgttt ctgcgccagc gcgctcattt gcgtaaaaat
     2941 cgtggtgcca agattgggca atttgctctt tggaatcagt gggttatttc tcattatctt
     3001 catacccgcc agtgatgtgg ttgttgacac actatcacag ggtgttagta tttggcaatc
     3061 aagacgttta gatgtctaaa tataataaca gcggtgagaa gaccctaagg acaacacaac
     3121 atgaaccaca ctgagatccg cgtcgttacc ggcccggcga attatttttc ccatgcagga
     3181 agcctcgaaa gactgaccga ctttttcacg ccggaacagc tttcccacgc tgtttgggtg
     3241 tacggcgaac gcgcgattgc cgccgcccgg ccttacctgc cggaagcgtt tgaacgtgct
     3301 ggcgcaaaac atctgcagtt taccggccat tgtagcgaac gccatgttgc ccaactggcg
     3361 cacgcctgca acgacgatcg tcaggtggta ataggcgtcg gcggcggcgc gctgctcgat
     3421 accgccaaag cgcacgcccg ccgtctggcg ctgccgtttg tcgctatccc gacgatcgcg
     3481 gcgacctgcg ccgcctggac accgctttcc gtctggtata acgacgcggg acaggcgtta
     3541 cagttcgaaa tttttgatga tgccaatttt ctggtgctgg tcgaaccgcg cattattctg
     3601 caggcgcccg atgactatct gttagctggc attggcgata cgctggcgaa atggtatgaa
     3661 gccgttgtgc ttgcgccgca gcctgaaacg ttgccattga ccgtaaggct gggcattaac
     3721 agcgcgtgcg ctattcgcga tctcctactg accagcagcg aacaagcatt agcggataaa
     3781 cagcagcgtc ggctgaccca ggcattttgc gacgtggtgg atgcgattat tgctggcggc
     3841 ggtatggtcg gcggcctcgg ggaacgctat acccgtgtcg ccgccgccca tgcggtacac
     3901 aacggtctga ccgtcctgcc gcaaacggaa aaattcctgc acggaacgaa agtggcttat
     3961 ggcattctgg tgcaaagcgc gctactggga caagatgacg tgctggcgca attgattaca
     4021 gcgtaccggc gatttcatct gccgacccgg cttagcgaac tggacgtgga tattcataac
     4081 accgcagaga tcgatagggt catcgcgcat accctgcgcc cggtcgaatc tatccactat
     4141 ttaccggtga cgttaacgcc agacaccctg cgtgcggcgt ttgaaaaagt tgaatttttc
     4201 agaatatagc ctggtggcgt tgcgcttgtc agacctggca accatcagca gcaacgcgcg
     4261 ccgccttttc caccatagcg cgcatcctgc cgctcgcgga aaaattcttc ataggtcatc
     4321 ggcgtctgat ccggatgcgt tatgcgcata tgttccacat agttgtcgta gtctggcacg
     4381 ccaatcatca tttttgctgc ctgtcccaga tattttccgg ctttcgaaag cgtatcgaac
     4441 atcgttgtca cctgtcatcc aaacgccctc tccttattct ggagagggct attgatgaaa
     4501 aaagattagt gcgcgccttt cgcttgcgtc acgatctcat ccacattttc cggcatcggc
     4561 tcatacggcg tttcattcgc cgtcggttta tcaatcttca gagcggccag cgccgtctta
     4621 atagagaaga ccgccagcac cacgaccacc accataaaga agatggttag cccggcatcc
     4681 agacggttat tgaataccaa ctgcgcgagc tgcgattcgg tgtactgcgg cggaatattg
     4741 ccgctgtcga tcatcgcctg gaatttattg gcaatggcca ggaagccgat tttcgcatcc
     4801 ggactaaacg ctttctgcca gcccgccgtc agcgtacaaa tcagcagcca ggccgtcggc
     4861 accagcgcga cccacgcata acgctgacgc ttcattttga aaagtaccac ggcgcaaagc
     4921 atcagcgcca tccccgccag catctggttg gcgatgccaa acagcggcca cagggtgtta
     4981 ataccgccca acggatcgac cacgccctga tggaggaaat acccccacgc cagcacgcac
     5041 aatgccgtag caagcaggtt cgctggcagc gaatcggtac gtttcagccc tggcgacact
     5101 acgcccaaca aatcctgcaa cataaagcgc gccgcacggg tacccgcatc caccgccgtc
     5161 agaataaaca gcgcttcaaa cagaatggcg aagtgatacc agaacgccac atccatcatg
     5221 ccgcccaacg cgccatgtaa aatgtaggcc atccctaccg ccagcgttgg cgcaccacct
     5281 gcgcgggaga taatggattg ttcgccgact tcattggcaa tctggtgtaa cgtatccggc
     5341 gtgatagcga acccccaact actgaccacc tgcgcggcag aagctacgac atccgctgtc
     5401 cccgctggcg ccagtaccgc catcgggcta ttcatcgcaa agtaaacgcc cggatcgata
     5461 atacaggcgg agaccagcgc cataatggcg acgaaagatt ccattaacat cccgccgtag
     5521 ccgataaagc aggcctggcc ttcgttggcc aacatcttcg gcgtcgtgcc ggaggagatg
     5581 agcgcatgga aaccggatac cgcgccgcag gcgatggtaa taaacaggaa cgggaacagg
     5641 tcgcccgtcc agacgggtcc ggtaccatca acaaatttgg tcagcgccgg catggtcagc
     5701 gtcggacgca taatcagaat cccgactgcc agaccgacaa tcgtaccaat tttcaggaag
     5761 gtagagaggt aatcacgcgg cgcgagcagc agccagaccg gcagtaccgc cgcgacaaaa
     5821 ccataaccca ccagcatcca ggtaagctgc acgccagtaa aatcaaagta cggcgcccag
     5881 gttgggcttg ccgccaccca tcccccggaa ataatagcga aaataagaaa taccagccca
     5941 atgaccgaca cctcgccgat gcgccccgga cgcagataac gcagatagat gcccataaaa
     6001 atcgccagtg gaatagtgaa cgcgacagtg tacgttcccc acgggctatg ggtcagcgct
     6061 ttcaccacga tcatcgccag gacggccaga atgatcacca tgatcataaa gcaggctacc
     6121 agcacgatca cccctgccgt cgcgcccatc tcctctttaa ccagctcgcc aagcgaacgc
     6181 ccatcgcgcc gggtcgagac gaacagcacc ataaagtcct gcaccgctcc cgccagcacg
     6241 acgcccgcca gcagccagat catccccggc agatagccca tctgcgccgc cagtaccggc
     6301 ccgaccagcg gacctgcgcc agcaatggcc gcaaaatggt gaccgaacag cactttttta
     6361 tcggtcggga cataatccag accatcatta tgacgtaccg cgggcgtcat acgcgttggg
     6421 tcaaccgcca gcactttttt ggcgatatag agcccataaa aacgatacgc aataagatag
     6481 acacagaccg acgccaccac gatccatagc gcgttgatct gttccccacg atttaacgca
     6541 atatagccta gggcaaacgc acccaatact gagagcgctg tccagacgag gtatttccct
     6601 gatttattca tagttgttgt ccgtttgggt gttccagaga gatgttacat tttgtttcta
     6661 tgacaccttt accgtaatta acaacacaac aacatgataa aaccggattg ttacccattt
     6721 tttacattac agtgttaacc agatcacttc ctttcttcgt taatgctgca attgcatttt
     6781 actttgccag aactatccca ttaccgccgt tcccaggcga caagtgcagc agcgcctccc
     6841 ctgctcgtca aagagcgtaa tttcccagct ttgattctgc cgccccagat gcagcggcag
     6901 gcaaacgccg cgtactttcc cctgcgagac ggcgcggtga tgggtggcgt ttaactcggt
     6961 cccgaccacg cactgcccgt cgcgggtcat cagataaccc gccattgatc ctaacgtctc
     7021 cgccagcgct gccgatgcgc cgccatgtag cagaccaaac ggttgatgag tgcgggcatc
     7081 gacgggcatt tccgcctcca gcacgtcatc gcccagacgg gtgtaaacaa tgcccagatg
     7141 cgccaccagc gtgttctgac tggtagcatt caattcatcc agcgttaaat gccgtttcca
     7201 gatcatcgtc aggctcccaa tgttgaaccg ccgtccacca cgatatcctg caaggtaatg
     7261 tggctggcca gatcggaggc aagaaacaaa atggtattgg ctatctcctg cggacgggcg
     7321 attttaccga gcggtatgcc gagcttaaac tgttcgccga aaccgcgaat gcgctgctgt
     7381 tcggcatctt cactcaccca taacgtgcgc tgcatatcgg tgtcggtcga gcccggcgac
     7441 accacattac agcgtacccc gcagcccgcc agctccagcc ctacggttag cgccaggctt
     7501 ttcagcgccg ctttagaggc gccgtaagcg cccataccga tacgcggcgt atgcgccgca
     7561 tctgaggcta cggtgacaat cgcccctccc tgctgacggc gaaactgcgc catcgtctgg
     7621 gaaaacaggt taaatgcccc gcccacattg accgcaaatg tctgctgcca gtcgtcgacg
     7681 ttaagcgcgt cggtcgctcc catacgcaaa ataccggcgg cgttgaccag cacatccagc
     7741 cgcggcgttt tttgcaacac acgctggcac acctgcgcaa cctgtgcggc atccgccaca
     7801 tccataactt cggtagcaaa gggataattc tcttgcgtaa attcgcgatc gaagccgatc
     7861 acccgcgccc cggcgtcgac aaacgccagc gccgtcgcgt aaccgatccc tttccccgcc
     7921 ccggtcaccc ataccgtttt gtctgaaaaa tcaaagctgg ccattactct accccgcgag
     7981 aaagcagcgc ccaccaggcg tcaatggtcg gatttttcgc cagcatcacg aagtcgatat
     8041 cgccgtgtac tttacgccag cgcgccgcca gccccatcat gcgtactgaa tccaggccat
     8101 aatcaatcag gttttcatca tccagcggct cgtcggtctc atccagtaac ggcagaatca
     8161 acgcccgcag cgccgcttta ctggcaggaa tcggcgtcgg cagcagcgac tctgtcatga
     8221 cgacgcgacc ggaacgcccc gccacatagt tcagcgccat cagatgctct tcccgactga
     8281 aatccgccag cgcatccgcc accataaacg gcttaatgtc gcgcataaac gcatcggtag
     8341 cggtggtcat acagccaata tgtgcatata cgccggtaat gatgagctga ttgcgtccgg
     8401 tatcttttaa catctgttcc agcggcgagc ggtgaaacgc gctataacgc cacttcacca
     8461 gcaccgtatc cgcctcatcc ggcgttaagg cttctaccac cttctgctgt tccggagagc
     8521 gcgtcagtcc cggtccccac atatcattga gtaacgcgcg atcttcatcg ctttgctctt
     8581 tcggctgagc ggtgtaataa accgggatat gatgttcctt acagtactgg cgcagagcgg
     8641 cgatattggc aattacctgg tccatcattg ggcaattgcg gccccaaaag ctgacaaagt
     8701 aatcctgcat atcgtggatg agcagcgccg cgcgctccgg ctcaaatgcc cagttcactt
     8761 tgttggtcgg gatatccagt gcggtgggca gcgcgtaaga ctgtagtttc gggattgcca
     8821 tctctctttc tccttcagag cggtgaacgt gacgccaacc gctggcgtaa ttgtttttta
     8881 tcgactttac caaccggcgt cagcggcagt gacgcaacgc actccacgcg atccggtaat
     8941 ttaaattccg ccacgccctg ctctcgcagg aaacggcgta cctgtaccgc tcgcagcggc
     9001 tcttttacca ccagatatgc gcaacttttt tcccccagca gttcatcttc catgctgacc
     9061 agcgccgcat ggatcaccgc cgggtggcgc agtaacaggt tttctatctc ttcggcggct
     9121 atcttctcgc cgccccggtt gatctgatct ttttcacgcc cgtgaacggt gatgtagccg
     9181 tcttgatcaa tggagatcag atcgccggaa cagtaaaaac cgttggcgtc aaaggcgctg
     9241 acattgtgtt gcggactgtt gaaatagccg cgaaaagtat aggggccgcg cgtcatcaga
     9301 cgaccaatct cgcccggcgg cagtggattc ccgtcggcat ccgccaccca cacttcgtcg
     9361 tccggacaca tgggtcttcc ctgggtattg ataatccgtt ccgggctatc gtccagccgg
     9421 gtatagttca ctaacccttc cgccatgccg aagacctgct gcaactgaca gccaatttca
     9481 gccggaatac gggcggccag cgtcgcagaa agccgcgcgc cgccaacctg caataacctt
     9541 aatgacgcca gcggcgcatt gccgccccac tcctggatag cctgtagcca tagactgacc
     9601 gcgggcggca ccagcgccgt ggcattaatc tggtgttttt cgatcagcgg gaaacagagc
     9661 gtggcgccag gatcggtcgc cagcactacc gttcctttgg cgagaaaaac gcccagcgcg
     9721 cccggcgaac tcatggcgta gttatgcgcg gcgggaatcg cgcacagaaa acgcgtctcc
     9781 tcgttgaaac cgcaaatctc attgctgcgg cgcacgctgt agtaatagtc gttatgggta
     9841 cggggaataa gctttggcgt gccggtagta ccgccggaaa gctgaaagta ggccacttcg
     9901 tcagcaggtg atggcgtggc ggtgaaacct tccgccgcct gccgcatcgc cgcgtccagg
     9961 ctgtgatcgc cgtcgtcgtt gcgcaataac accacccgcg cagagcggtg ttcagccaca
    10021 aacctgttga gaaagtcctc cccggcgaac agcgtatgtt ggcgatcggc aatcaccagc
    10081 gtcggcgcga tctgcatcgc ataggcgtta agttcggtac gttgatggct aaacagcgcc
    10141 agaacgggcg ctacgccaag cttcaacagg gcgaaaaagg tgatatacag ttccggtaca
    10201 ttccccagtt gtaccagagc ggtttcgcca ggtttgatgc cctgacggcg taaactgcag
    10261 gccagattat ccgcggcctg gtttagctgg cgatagctga atgcgcgctc gccttcaatg
    10321 accgccgtct tatcgctgtc agcgtggcgg gtcagaatat cggtcaacgg cacgtcttgc
    10381 cagtagcctt tttcacgata acggcgggca aattcatccg gccaacgggt gaaaggtata
    10441 cgcatcatcg ttccttaatg cagtccaaaa acgttcaaca tcgtagagag cttgacgccg
    10501 gtttcccgcc actcgccgac tggcgaagag gcaggaacaa tcccggcgcc ggcgaacagg
    10561 cgcacctgat taccgtgcaa tttcgcacaa cgaatcgtca ctacccactc gccgtttcct
    10621 tcggcatcgc accagccgac aatgccgcca aacagttcac gatcgaacgg ctccagttca
    10681 gcaatcagct ttttcgcgac ctgatggggg aaaccgctta acgcaggggt cggatgcagc
    10741 agacaggcca gcgtaagcgc gttttctccg gcgttggcct tgccctcaaa cggcgtaccg
    10801 agatgccata gcgtcggcgt ggtgatcaac tgcggagagg aaggtaattg cagttccgtg
    10861 ctgcgatcgc gcaggatctg cttcatcgcc tgcgtcacca gctcatgttc atggcgatct
    10921 ttttgtgaag ccagcagtcg gtttcccgcc tcgcgatcca gaacgtcatc gggctgtcgg
    10981 cgtgccgagc ctgctaacgg cagcgaacta aaccgctcgc cctccttgcg tagcagcaat
    11041 tcggggctgg cgcccagcag aacgccgcca tccgccagtg gcacatggaa gttgtaacta
    11101 actggattct gcgcaaccag ccgctccagc aatgctccgc tatccaccgc cacatcagtg
    11161 gtgatatcta tcagccggga aagcaccact ttatcgacgt ctggcgtggc ggtcagcata
    11221 gccgcgcgtg cgaccatcgc ttcaaaagca tcctgctccg gaatcgcctt tcgcgccgtc
    11281 accgtcagcg gctgatggtc agtaaaataa cgcgccgtgc gctgcttttg ctggcgggaa
    11341 aaggactgcc acgccatcgg gataaatagc gacgacggct gacgggtatc aaaggggatc
    11401 gcccccacca ggatagggtt ggcgatgccc tgcgatttgg cctcggcaaa ctgctggcgc
    11461 aatttctgct ggaaagggct atccggcgaa tctccggcaa ccgcaggctc ggtataacgg
    11521 gcgaagcacc cggaagtggt aaaactgcga tacggcgaca tgaagaaaaa gcgatcggga
    11581 gcaagcgttg ccattgtctc ctgagcgtcc tcggccagtg acatatccat atcatcctcc
    11641 aatgataaag gcttatatac acttcatctt tcaagctgcc tctttgttgg ctgcgatcag
    11701 aaaccccggt cacacagtta tctatgcccg cggggattct tcccttgccg tcgcgatgct
    11761 tcttgaatga ttttgtgtat aataatgatt attatttcta tttttagtgc gctaacctaa
    11821 gagtaaaacg tcgctctgtc aactctggtc atgagttaaa tggcactaag gcttgcatct
    11881 cgctgccgct gacatgaaaa tgagaagcat taactttatt aataacagga cgctattgtg
    11941 agactctccg ccttttatcg ttggctgctt ttagtggttg gtttatcaat ttcaggaata
    12001 tccttagccc aggacgccgg ttggccccgg caaatccagg acagccgagg cgttcatact
    12061 ctggaccaca aacccgcgcg tatcgtctct accagcgtga cgttaacagg ctcgctgctg
    12121 gcgattgatg cgcccgtcgt cgccagcgga gccactacgc cgaataaccg ttttgccgac
    12181 gatcaagggt ttatgcgcca gtggagcgat gtagcaaagg ctcgccatgt cgcccggctg
    12241 tacatcggcg aaccgaatgc cgaaacggtc gccgcgcaaa tgccggatct cattttgatt
    12301 agcgccaccg gcggcgactc cgcgctggcg ctttacgatc agctctccgc catcgcgccg
    12361 acactcgtca tcaattatga cgataaaagc tggcagagtt tgctcacgca gcttggcgag
    12421 atcaccggtc aggagaaaca ggccgccgcg cgaatagcgg aatttgaggc gcaactgacg
    12481 acggttaaac agcgaatcgc cctgccgccg cagccggtta gcgcgctggt gtatactcct
    12541 gccgcgcata gcgccaatct gtggacgcca gaatcagcac aaggcaagct attgacgcag
    12601 ttaggcttta cgctggcgac attgccccaa gggctgcaaa ccagcaaaag ccagggtaag
    12661 cgccacgata tcattcagct tggcggtgaa aatctggccg ccgggttaaa cggcgaatct
    12721 cttttcctgt ttgccggcga caacaacgat gttgcggccc tttacgccaa tccgctgctg
    12781 gcgcacctgc cagcggtgca aaataagcgc gtctatgccc tgggtacgga gacgttccgt
    12841 ctggattatt acagcgcaac gttgctgctt aatcgactgg ccgccctgtt ttagccttat
    12901 cggagtctta tccgactgac cagacagatt tggtcagtcg gataaacgcg tcttcatcag
    12961 ccagcatcgc taaccggcgg cgtctggcga aaacggcgta gctcgcccag cactaacagc
    13021 agcagcaaac cgataatcac cagcccgaat ccactcacgc tcgcggaagc gaccggcgtc
    13081 atcattgcgc caagaccgcc taacagcgcc gcgccgatag cgtctcccgt gacgttttgc
    13141 gcggtccaca ggccgttcat tcgccccagc atattttccg gcgtctgggt ttgcagcaga
    13201 gtgtattgta ataacgaact gatggcgcta agccagccaa atagcgccag acagataaca
    13261 ccagcgatcc agatcggcat gatggcgaac agccccaccg ccagaaaaga accgactgtc
    13321 gaaaccagca taatgagccc cggacgaacg ctatgcgcca gttgtccgct ggtcagcgcg
    13381 ccaatggccg cccccagcgg aattgccgca tacagcaaac cgatttgcgc cgccgacatc
    13441 tgccagctca tcgccagcgc cggatagagg acgcgtaccg cgcttgccat cgtcaccagg
    13501 ccgccaagca gcgcaatacc gccgataagc ggactggcga gcaaaaaacg aaatgccgcc
    13561 agtaacgcga taaatggatt ttcccgcggc tgcggaggaa caggcagtcg cggcagcgtc
    13621 agtaacggca atagcgtaat aaacgtcccg gcggccgcca gcccatagtt ccaggctacg
    13681 ccgccgctgg caagcaatat gccccccaac atcggcgaaa taaccgatcc cagacgtacc
    13741 gtcagcatgg taatcgcgcc ggcctgcatc agattttctc ttccgaccag cgctggcgtc
    13801 gccgccagta acgcggtcac gcccagagac gcgaaaaagc cgtcccacag gccaaggaga
    13861 tatatcgcca gcaatgacgg ttccggcagc agcgcgttca cgcacagacc aataaagcca
    13921 ataccgcaag taccgcgcgc cagcagaatc acctttttgc gttcgtagcg atcggccagt
    13981 acgccgccca ccattaagcc aataaacatg gcgccgccgg ttaacgttac cgacagccct
    14041 acctgccagg tagagtgcgt catcatttgg atctgtaccg gaaccgccac gccaagcagc
    14101 cccagcgaga caatagagat aaaacgggcc agaaatactg cgcgaaatgc agggtgcgtc
    14161 ttcaacaggc tgagattgag cagccaggat tgtcgattca ttacaacgcc ttaatgcgag
    14221 tttttttaaa tatccattca atggctgcac atgctaatat aaccaaataa gatagataac
    14281 gataattact atcattatca gggaagttac tatgtcatgc tcgttttccg tgacgcgcgc
    14341 gtttgccgtg cccggattgt tgttattact gagtctcgcc gcggttttaa gcctggtcat
    14401 tggcgcgaaa ccgctgcccg ccgccgtcgt gctggaggcg ttcaccggcg tgtgccaaag
    14461 cgccgattgc accatcgtcc tggatgcgcg tttgccgcgt acgctggccg gattactggc
    14521 aggcggcgca ttgggtctcg ccggggcgct catgcaaaca ctcactcgta acccgctcgc
    14581 cgacccgggg attctgggcg ttaacaacgg cgccagcttc gccattgtac tgggcgcggc
    14641 gctgtttggt ttctccacgc cgctggaaca gcttttcatg gcatttagcg gcgcgcttat
    14701 cgcatcgctg attgtcgcct tcaccggtag tcagggcggc ggccaattaa gcccggtccg
    14761 cctgacactg gcgggcgtgg cgcttggcgc ggtactggaa ggactaacca gcggcatcgc
    14821 gttgttaaat ccagaggtct atgaccagct tcgcttctgg caggcgggat cgctggacat
    14881 tcgtagcctg caaacgttga aagtcgcgct cgcgcccgtg gttatcgctg ggatcgtggc
    14941 gctatttctg agccgagcgc tgaacagcct gagcctcggc agcgataccg cgacggcgct
    15001 ggggagtaaa gtggcgcgca cccaacttat tggtttactg gcgattaccg tcttgtgcgg
    15061 cagcgcaacg gcgctggtcg gccctatcgc ctttattggt ctgatgatgc cgcatatggc
    15121 gcgttggctg gtgggcgcag accaccgttg gtcgctgccg gtaacactac tggcaacccc
    15181 tgctctgctg ctttttgccg atattattgg tcgtctgtta gtgccgggcg aactccgcgt
    15241 atcggtcgtc agtgcgttta tcggcgcgcc ggtacttatc tttctggtac gccgtaaatc
    15301 gagcggaggc ggcctgtgat gtttctttct cgtcggctta tcgtaagctg cctgcttctg
    15361 gcggctggct gcttcgccat tggcttatgg agcctgcaaa gcggcgccgt gccccttgag
    15421 accgggcaga ttattgccgc gctgctgggc gacgcgccgc gtaatatcac ccttgtcgta
    15481 accgaatggc gactaccgcg cgtattaatg gcgctactga ttggcgctgc gcttggcgtc
    15541 agtggcgcga tttttcagtc gttgatgcgt aacccgctag gcagccctga tgtgatgggc
    15601 tttaataccg gcgcctggag cggcgtactg gtcgcaatgg tcctgtttgg ccagcatctt
    15661 accgcgatcg cgctggcggc aatggcgggc ggtatcgtca cgtcattgat tgtctggctg
    15721 ctcgcctggc gtaacgggat tgaaactttc cggctgatta tcatcggtat cggcatccgc
    15781 gcgatgttag tcgcctttaa tacctggctt ctgttgcagg cgtcgctgga aacggcgctc
    15841 accgccggct tatggaacgc cgggtcgctc aacggtctga catgggcaaa aacctggcct
    15901 tcggcgccgc tgattatggt gatgctgaca ggcgccgcgc tactggtgcg tcgtatgcgg
    15961 ctgctggaga tgggcgatga cagcgcctgc gcgctgggtg ttagcgtgga gcggtcacgc
    16021 ctgatgctga tgctggtggc ggtgtcgctc accgctgctg caacggcact ggctggcccc
    16081 atctcgttta ttgcccttgt cgcgccgcac atcgcccgtc gtcttagcgg cacagcgcgc
    16141 tggggattaa cccagtcggc gctgtgcggc gcgttattac tactggccgc cgatgcgtgc
    16201 gcgcagcaac tgtttatgcc ttatcagctt ccagtgggcg tggtcaccgt cagcctcggc
    16261 ggtatttacc ttatcgtctt gttaattcag gagtcccgca aaaaatgacc gaatccgtag
    16321 cccgtttgcg cggcgaccag ttaacgctgg gttatggcag ctataccgtc gcaaaaaacc
    16381 ttaatgtttc gattccggac ggccatttta ccgccatcat cggccctaac ggctgcggca
    16441 agtcgacgtt gctacgtacg ctaagccgtc tgatgacgcc tgttgacggc catgtctggc
    16501 tggatggcga acaaatacag cgttacgcca gtaaagaggt ggcgcggcgc atcggattgc
    16561 tggcgcaaaa cgccaccacg ccgggcgata tcaccgtaca agaactggtc gccagagggc
    16621 gttatccgca tcagccgtta tttacccgct ggcgcaagga agatgccgac gccgtcgcca
    16681 gtgctatgcg tgcaacaggt atcacctcac tggcggcgca aagcgtagac acgctgtccg
    16741 gcggccaacg tcagcgggcg tggatagcca tggtgctggc gcaggaaacg tccatcatgc
    16801 tgctggatga gccgacaacg tggctggata ttagccatca aattgatttg ttggaattgt
    16861 taagcgatct caaccgtgaa aaaggctata cgctagccgc cgtcctgcac gacctgaatc
    16921 aggcctgccg atacgccaca catttgattg cattacgcga aggtaacatt gtcgcacagg
    16981 gcgcgccgaa agagattgtt accgctgagc ttatcgaaaa aatctatggg ctgcgctgta
    17041 tgattatcga cgatccggtt gccgggacgc cgctggtggt accgctgggg cggcgatagt
    17101 cgcccacaca gatgacaaag ccggatatcg ctatccggct tttcgggtaa atcagactaa
    17161 ccgttcatct atcgccagcg cgttttccat tttacgcgag accatcgcgt gacgcagtaa
    17221 tacgccgccg caggccatca taccgccaat caacgccgcc aggataataa tgatcgcttt
    17281 acccgggcca tcttttttca ctggcagaga cggcgacagt tgatatttaa acggggtaaa
    17341 cttcacgtcg ctcacattca ttgccgccag ttgttcaaca tagtattgac ggttacgcaa
    17401 atcaccgtcg atctcggcca cgtccgttac ccctttttca atttccagtt tgcgggaaat
    17461 accatccgcg ccgagggaaa tagaaaaatc cggatcatct tttaccgcct gaccattact
    17521 gtaaaccggt ctcttaatgc cagcggcgtt ggcgatttcc agcgaataat gaagacgttg
    17581 aatattggca tcaagctgat ttttgagacg cacccgatcc atcgccagct tttcctgctc
    17641 gtagcgggtt ttgatttcca gctggttacg aatattttcc agcgtctctt tcacgacgat
    17701 atcggagatg tactgaatat agccagccaa cactttttgc gcttcttccc gcgtcggcgc
    17761 ggtaaaactc agcgtccacg acgtgaataa cgacgtttca tttttcttgc cggcattgct
    17821 gtccaccgct ttcatttttt cgctcagcac gacaatcgcc cggtgaagat cctgctcgtc
    17881 tatttgcgcg ccttttaatt gatccatgac atacggagaa gaacgaagat attcttccag
    17941 cagcgagggc gagctaaact ttttaataaa cagattaaat acgctggccc gatcaacgct
    18001 tacctccata tccaacacgc gcagcgcggt caacgttctc tccagcccct gctactgtac
    18061 cgactccgcc ggtgtgacaa tcgcctggct ggtccatttt tgcggcagca gaaaggacag
    18121 aagcaacccc acgcacgcaa aggcgaaaac ggtagcaaga atacgacgtt tcgcctgcca
    18181 taacacctct ataaggctaa acaaatcgat ttcatgactg ttggcgggcg gcagtgagta
    18241 acctgcaaat gactgatttt tctcttgttt tacattaaga gatggcatgc cgtatgacct
    18301 gaaaacttta tccaatgaaa gaacacattc ctgtcagaga ttctaacagc aagtcagaat
    18361 tatccgaaac aatctttacg cgccagtgcc cgaaaagcta aatattcgga attaaacttg
    18421 cctgtagcat gtatcactta tgttaaaaga attaatagtt gcaataaaaa acccataata
    18481 attagtcatt attatgggtt tcaggattta atttgttaaa ggcagaaaca acgcccgtta
    18541 tttattaata agttcgctga tgatgggccc gatagtttca aaagcggagg gagaaataat
    18601 atctacatgc gcgcacggct ggcgataaat agccaaagac gctatccacg gcgaccagct
    18661 ctgttcaggc gatacgtctt ccggcaccgt tttatccgcc acaaagagcg tggcatgtcc
    18721 atcaaacggt gcgctatgcg ccgtcgtcag caaacggacg gcatccgcat aattgccttc
    18781 aatggcggta aataaggcgt cggaggcatt tccctgctgc gcggcgacaa acgctgcgcg
    18841 ttcgcgttca atttccgcca atacgtccgg attgaggcca ttcgcctctt ttccccgcca
    18901 gttttgtgtt tccggcggcc aggtgtccag taaccccaaa aacgccaccg tttcaccgcg
    18961 cgcgcgcaac cgggcggcga tcccttgcgc cagcgtcccg cccagcgaat agcctaataa
    19021 ataataaggg ccatgcggct gccgggcgag caatgtcgcc agatgatgtt cacatacctc
    19081 atcaagggtg gttgcgattt gcatagggcc aacggggcgc ggcgactgaa tccccataat
    19141 cgaccacgac gggctgagat agcgtgataa tacgctaaat tgccaggcga accccgacgc
    19201 cggatggaaa caaaataacg ttggaccatc gctttcacgc agcggcaaca gcggcccgaa
    19261 ccccagattg cgcgagcgtt cgtcatcgtc agtatcgagc agcttactca actgcgccac
    19321 gtcagacgcc accatcacct gccccggcgt cacctggcgg ttaaacgtct ggcttagctg
    19381 cgcggccagt ttcatcgcca gcagcgagtg tccgcccagc gcaaagaaat cactttcaac
    19441 gtcgttaatc tcacagccca gcaggcggga aaacgccgcg gcgacagcaa tctccgttgc
    19501 ggactgcggc gcacgccctt tcacgcgcgg cgtcagatcc ggcagcggca gggctttgcg
    19561 atccagcttg ccattagcgc taagcggcaa gctggcaagt tgcaacagca caaccggcac
    19621 catatgcgcg ggaagttttt ggcgtaattt atcctgcagc gccggtaaat ccagcggtaa
    19681 accggagtgc gacaccagat agccgaccag ttgccgggca tccccgcccg tcgccgccgc
    19741 ctgattaaag acgcaggcat gtgctaccgc ctgttcaaca tccggcagcg tttgcatgac
    19801 gcggtcaatc tcacccagtt caatacgttg cccccgaatt ttgagctgat cgtcgctgcg
    19861 tcccaggtac tccaccacgc cggaatccag ccagcgcgcc acatctccgg tacggtacat
    19921 ccgttcacct ggcgcaaaag gatcggcgat aaaacggctg gcggtaagat ccggacgccc
    19981 cagatagccc tgcgccagtt ggataccggt aagatagaga tcgccagcca cgcccggcgg
    20041 caccggctgc atatgcgcat cgagaatacg taaaccggta ttccagacgg gataaccaat
    20101 cgggatactg ttgccgtcaa cagccgccag ctcatcgcca caggccggat accagctcac
    20161 atccaccgcg gcctccgttg gcccgtacag attgtgtagc ggcgcgttgg ttaacgtctc
    20221 ccattcgcgg cacagcgccg tcggcagggc ctcgccgcta cagaaaacgc gctttaagga
    20281 agcgcagctt ttcccagccg acgctggcgt gagcgaggca ataaaggccg ccagcatcga
    20341 cggcacaaaa tgggtggtcg tgacgccgta ttgcgcaaag aaccgctgca tcgcgagcgg
    20401 atcgcggtgc gcttccggtt cagccatcac cagtttcgcc ccggcgataa acggccagaa
    20461 aaactcccat actgagacgt caaaactgca cggtgttttt tgcgctacta catcatccgc
    20521 cgtcaacgga tagtgatcct gcatccacag cagccggttg actatcgccg tttgtcccac
    20581 catcacccct ttcggcctgc ccgtcgaacc agaggtgaaa atgatgtaag cggtatgatg
    20641 cggtagcgac agccccagcg gagtggcgtc actgaccggt agcggttggc tataacacaa
    20701 atattccatc cccggaatat cgtgaaagcg cgccagctgc gcctgagtcg taattaacag
    20761 tttcggctgc gcatcttcca gcatcattcg cagccgatcg tcaggataac cggtatccag
    20821 cggcagccag gcggcgcccg cttcgacaat gccgtgcagc gctaaggtca gaaaaaccga
    20881 ccgcggcaac gccaccgcca cgctatcgcc aggctgaacg ccgcgttccc gcagcgcgta
    20941 tgccagcgcc acaacctgtt cgcgcatttc acggtaggta aagtgataat gcgcatctgc
    21001 caacgcggaa gcctctggcg ttttttgcgc ctgctgcgcc accaaatcgc taagcgtggc
    21061 ggcgggaatc gttaccgccg tattattaag gtgtgttaat tgcgtttgtt cttccgccag
    21121 cagcatttgc gcatcgccgc agcgcagcgc cgggttatca gcaaactgcg tgataagcgc
    21181 catcaaccgt aaggcatggc gggaaagcgt ggcgtcatcg taacgctgcg cattcgccag
    21241 caattcaata tccagaccgc cgttttcatc cggaaaaagc gccagttcaa gatcgttaac
    21301 cggccccgtc gccagggtat gggtttgcgc ctgtatgcca ggaaaatcca gatgataatc
    21361 aaatactttt atgttgagca ccgggccaaa tagcggcgtt tcccctgcgg ctcgcccgct
    21421 atcgcgtaca atctgttcgg cgtcgtaacg ctggtggcgg cgcatcttct ttaactgcgc
    21481 cgcaagacgc ttcgccagcg ttggcagatc ttccgtcgca tgaaggttaa ccgccagcgg
    21541 caacacgtta aggacaggcc cggtcgccgt taacgccgct gagcccatcc gccgcataaa
    21601 gataaatccg gcggcataat ccatacgccc acataatcgt cccagccaca acgtcaccag
    21661 cgccagggca agatccgctc gcggtatctc aggcatgtgc gccgccagtt ggcgaaacgc
    21721 ccccgccggc gcgctcaatt tcatacgcag aatatccgcg ctcgccgacc gccccggcaa
    21781 cggcgcggca gacattgacg ccggcggcgg cagctcgcgg cgctgctgcg cccagaaggc
    21841 gccgtcacgc tgccaggcct cgctctggcg atagcgctga tattcctcaa ccacatccac
    21901 aaagggggta aaaggcgact ccggcgtagg ggcgtcgctc tgccaggcgc gataaatcgc
    21961 cgcaatctgg cgagttatcg ccgggaagct aaagccatcc accagcaaat ggtgatagcg
    22021 ctgataccaa taccagcggg tatcatcaat gcggattaac tggtgaaacg ccagcggctt
    22081 accgctatct gcgcgcaggt tttgccgtaa atccgcctgc attaacgcca gcgccgcgag
    22141 atgcggatcg ggctggtcgc gtaaatcggc aatcgggggt tcgccgaagg tgtgctcagg
    22201 atctatccat tgccagacct cgccgttctc ttcggtaaaa cgcatccgta gcgtatccgc
    22261 ctgttgcatc cctaccgcta ccgcttttgc cagcaagggg gcatccagct cgccattcag
    22321 ttccacatag tgcgccacgc tccaggcgga gggtaaatca gagagttttt ccgccatcca
    22381 gatccccggc tgggcggcga ctaacggtaa acgctgcgtc atttcgcctc ctgcttatcg
    22441 gcataatgcg ccggattcag tgttgtccag cgcgtattaa gccactgctg gcacgcgtcc
    22501 tgcgattgcg gttcgcatac cacgccccat cctgcgggaa gcgcgcacgc cgctggccaa
    22561 aggctgaatt gacgctgcgc attttgcagg atgtaaaact gtccctgcgg attatcgaag
    22621 ggattactga attccatact caactcctgt catggacatg tgcccggtta aagcgtgtcg
    22681 ataagcggct gccaaagcag catcagccct tgcgttagcc cgccgcgcca gcaaagcgca
    22741 tcgtgtccgc cgtcaacctg acgccagaaa atggactgct gcgaggtatt cagttgggca
    22801 taaagcgcct gatttgcctg aaacacgatc ggctcacgca cgccggcttc cagtacgata
    22861 cgcagtccgc gcgcgcacaa tgcgccggtt ttcagccggg taatgacttc cccctccggc
    22921 ggggtgatgc gatggggcca ccagaacgat cctgactggc ttagtacaca gccaaaacgc
    22981 gtcggccagt tcaggccggc atacagcgcc gacaggccac caaagctctg tccggcgacc
    23041 accgttcgtc cggcatcatc gctaaaaggc gtcacggctc tgacttgcgg caacagttcc
    23101 tgctgcaccg ccagccagaa gtcggcattg cagggcaact cctggttgcg gtgttgagta
    23161 tcaatcgcgt caatcagcag atagacggca ccgggaagca ggcgttgatg agtcagcgag
    23221 gcgagcgcgg gccagacggg catattttcc gcccagaatt gaccgtccag cagaatagcc
    23281 aacggtcttt cctccgtcgc ctcgtctccg gtcgtcaata tccatacgcg gcgggagtta
    23341 cccagacgtt cgctatgcca ctgcatcatc aaaggcggtg agtacgacgt ttcaggacga
    23401 tcccatcccg gctgacgggg cgcatccggc atttccagcg ctgaaaccgc atgaccacgt
    23461 cctccccgcc agctttgcga attaagcggg tcggcaatcg cctgcggtaa tagctgtcgc
    23521 cagccttcac gcagcgcgtt ccgatcgggc gtttcgcccg gcgcaaaagc ggcaaaaacg
    23581 tcatctcgct cggtaggaat aaaacagtag ctgccgcgcc agttagcgct aagcgccgtg
    23641 ctccagcgcc agacatccgt tccggcaata cgcgccatcg tctgaggctg cgcgttttga
    23701 tgatgatcgg ttacgccagt gatgtagacc cagacacgcc gtatcgggga gtgtgtttcg
    23761 tttccctgcg ggtcgcgcca ccaaaaagtg acccgataat ttccgtcttt ttcccgtatc
    23821 cattccggcc cggttttcgt cctccaccag gcctcacttc ccgttgccag cgcctctttc
    23881 attataaccc tgtgtttatt atgaattttg tatataaaag gtgaaatata ttgataatat
    23941 tattgataac tatttgcatt tgcaatagcg tattgtagcg ctatgggacg cgcgaacaca
    24001 atttcaccac ccggccaatg cctttgacgg gcgctttggc ttatgtggct aaagaaaagc
    24061 aggatataca atgaacaaga agattcattc cctgacctta ctggtcaatt tagggattta
    24121 cggggccgct ctgcccgtga tggcggaaga aaaaaccgat agcgctgcgc tcaccaatga
    24181 agacaccatc gtggtgaccg ctgcccagca aaacctacag gcgccaggcg tatccaccat
    24241 caccgccgat gagatccgca aaaatccgcc cgcgcgcgac gtgtcagaaa tcatccgcac
    24301 catgccgggc gtaaacctga ccggcaactc caccagcggt cagcgcggga ataaccgcca
    24361 aatcgatatt cgcggcatgg ggccggaaaa cacccttatc ctgatagacg gtaaacccgt
    24421 taccagccgt aactcggtac gcctgggctg gcgcggcgaa cgcgataccc gcggcgatac
    24481 cgcgtgggtg ccgccagaga tgatcgaacg cattgaagtg ctgcgtggcc ctgccgccgc
    24541 acgttacggt aacggcgcgg cgggtggcgt ggtcaatatc attaccaaaa aaggcggtag
    24601 cgagtggcac ggttcctgga atacctattt caacgcgccg gaacataaag acgaaggcgc
    24661 gaccaaacgc actaacttta gcctgaacgg cccgctgggc ggggatttca gcttccgtct
    24721 gtatggcaac ctcgacaaaa cgcaggcgga tgcgcgtaat attaaccagg ggcatcagtc
    24781 tgaacgtacc gggagttacg ccgacacgtt accagccgga cgcgaggggg tcattaacaa
    24841 agatatcaac ggcgtggttc gttgggattt tgctccgctt cagtctctgg agctggaggc
    24901 cggttacagt cgccagggca acctctatgc cggcgatact cagaacacca atacgaacca
    24961 actggtgaaa gataattacg gaaaagagac gaaccgcctc tatcggcaga actactctct
    25021 gacctggaac ggcggctggg ataatggcgt aaccaccagt aactgggtgc aatacgaaca
    25081 tacccgtaac tcccggatgc cggaaggcct ggcaggcggc accgaaggga ttttcgatcc
    25141 caaagcatcg caaaaatatg ccgatgccga tttgaatgac gtcaccctac acagcgaagt
    25201 gagccttcct ttcgatctgc tggtcaatca aaacctgacg ctgggtaccg aatgggccca
    25261 acagcgtatg aaagaccagc tctccaactc gcaaaccttt atggggggaa atatcccggg
    25321 ttacagcagt accaatcgta gcccctattc aaaagcggaa attttctctc tgtttgctga
    25381 aaacaacatg gaactgaccg acagcaccat gctgacgccg gggatacgtt tcgatcatca
    25441 cagtattgtg ggggataact ggagcccgtc gctgaacctg tcgcaaggtc tgggggatga
    25501 ctttaccctg aaaatgggga tcgcccgcgc ttataaagcc ccgagtctgt accagactaa
    25561 cccaaactat attttgtaca gtaaaggtca gggttgctac gcgactggcg cgggtaccgg
    25621 catcggctgc tatatgatgg gtaacgatga tctgaaagcc gaaaccagca tcaataaaga
    25681 gatcggtctg gaatttaaac gcgatggctg gctggccggc gtcacctggt tccgcaatga
    25741 ttaccgcaat aagattgaag cgggtacggt gccgttgcag cgtatcaata acggcaaaac
    25801 ggatgtctat cagtgggaga acgtgccgaa agcggtcgtt gaaggtctgg aaggcacgtt
    25861 aaacgtaccg gttagcgaca ccgtcaactg gacgaataac gttacgtata tgctgcagag
    25921 taaaaacaaa gagaccggcg aacgcctgtc gattattcca cagtacacgc ttaactctac
    25981 cctgagctgg caggtacgtc aggacgtttc tctgcaatcg accttcacct ggtacggcaa
    26041 acaagagccg aagaaatatg attatcaggg taaccccgtt accggaacag ataagcaagc
    26101 ggtcagccca tacagtattg ttggcctgag cgcgacctgg gacgtgacca aaaatgtcag
    26161 cctgaccggt ggcgtggata acctctttga caaacgtctg tggcgtgaag gtaacgcgca
    26221 aaccgtcagg gatacgcaaa ctggcgctta tatggcgggc gctggcgcgt acacctataa
    26281 cgaaccggga cgtacgtggt atatgagcat taatacccat ttctgatggc aaccttccct
    26341 ccctcattcg gggagggaat tagcaaaaga cgatgctgac atctcatttt ccccttccct
    26401 ttgccggaca caggctgcat atcgtcgact ttgatgcgag cagctttcac gaacacgacc
    26461 tgctatggct gcctcatcac gatcggctcc ggtctgccgg acgcaagcgt aaagctgaac
    26521 atctggcagg ccgcatcgct gccgttcatg cgctacgcga ggtgggcgtc agggcggtgc
    26581 ccggtattgg cgacaagcga cagccgctat ggccggacgg cctatttggc agcatcagcc
    26641 actgtgcgtc aacggcgctg gccgtcatat cccgacagcg tgtcggcgtt gatatagaaa
    26701 aaatcatgag tcagcacacg gcgacagagc tggcgccgtc cattattgat agcgatgagc
    26761 gccaaattct ccaggcgagc tcgctccctt ttccgcttgc cctgacgctg gctttctccg
    26821 ccaaagagag cgtttataaa gccttttcag accgcgtcac gctcccggga ttcgatagcg
    26881 caaaaattac ctcgcttaac gccacgcaca tctcgttaca tctgctgcca gcctttgccg
    26941 ccatgatggc tgaacgtacc gtccgtacag aatggtttca acgtggcaat agcgttatta
    27001 ctctagtttc tgcaataacg cgctttcccc acgacaggag cgctcccgct tctatactta
    27061 gcgcaatacc ccgataaatg agatcgctat ggcgctgaat gattttcacg tttctgaacc
    27121 ttatacgctc ggtattgagc tggagatgca ggtgatcaat ccacctggct acgatttaag
    27181 tcaggactct tctacgctga tcgacgccgt taagccccaa cttactgcgg gagaaattaa
    27241 gcacgatatc accgaaagta tgctggagat ggccacgggc gtctgccgcg atattgacca
    27301 ggtggcggcc caactttctg ccatgcagca cgttatttta caggcggcgt cggaacacca
    27361 tctcggcatt tgcggcggcg gtacgcaccc ttttcaaaaa tggcagcgtc aggaggtctg
    27421 tgataatgag cgctatcaac gcacgctgga aaatttcggc tacttaattc aacaggcgac
    27481 ggttttcggt cagcatgtcc acgtcggctg cgcgaacggc gacgatgcga tttatctttt
    27541 acacgggctg tcgcattttg tgccgcactt tattgcgctc tccgccgcgt ctccctatat
    27601 gcaaggatct gacacccgtt ttgcctgcgc gcgcctgaat attttttccg cttttcccga
    27661 taacgggccc atgccgtggg tcagtaactg gcaagagttt gccggactat ttcgtcgtct
    27721 gtcttacacc acgatgatcg acagcatcaa agatttgcac tgggatatcc gccccagccc
    27781 ggcctttggc acggttgagg ttcgggtgat ggatacgccg ctcactcttg atcatgccat
    27841 caatatggca ggattgattc aggcgaccgc gcactggctg ctgaccgagc gtccctttaa
    27901 accgcaggaa caagactatc tgttatataa attcaaccgt tttcaggctt gccgctatgg
    27961 tctggagggc gtgctaaccg atgtctatac cggcgaccgc cgtcgcctgg cagatgatac
    28021 gctgcgtctg ctggacaacg ttaccccctc tgcgcgtaag ctgggcgccg acagcgccat
    28081 tgacgcgcta cgtttgcagg tgaaaaaagg cggtaacgaa gcgcaatata tgcgggagtt
    28141 tattgccgac ggcggatcgc tgataggcct ggtacaaaaa cattgtgaaa tctgggcggg
    28201 acaatagaca gcatatttgc cttaccaggc gatgtcccgg acaatggcgt tttaacttac
    28261 gtttaacaaa gccatgaaac acccgcttga atcattgatg accgctgccg gtattttgct
    28321 gatggcgttg ctctccagcc tgctgctgcc cgccccttcg ctcggccttg cgctggcgca
    28381 aaaactggtc gggatctttc atcttatgga tctcaaccag ctttatactt tgttgttttg
    28441 tttatggttt ctgttgctcg gcacgctgga atattatgtt attcgcttta tctggcggcg
    28501 ctggttttcg ctggccgatt aaacatttca atgcgtacgg ccatgctttt ctttacgata
    28561 agcgcctggc ggcaggttga acgtgcgggt aaaaatgcgc gtaaaggttt gctgcgaatc
    28621 aaaaccatac ttgagacaaa tatcatacac cttctggtcg gtgtcgcgca ggtcgcgcgc
    28681 cgccagtttt agcttccgtt cacgcacgta gcgcctcaga ctctcccctt tgtactgcat
    28741 aaaaaggcgc tgcaggtgcc acttggaata ccccgcatga cgggcaatat catcaatacg
    28801 taacggctga ttcaaattat catcaatcca ctcgacaatc gtgtcgataa cctgagcgga
    28861 aatggtcatc gtgctctccc ctctatcaaa ctcgtcagcg gctcccgcac cgcacattta
    28921 cggcaacagc aataagcata gtaataacca cacaaattgt gagacggctt atcgcatggc
    28981 ctgcaatatg cttttctacc acttcatgcg gcagcccttg attatgagtg agtaagcact
    29041 cattatagaa agcaaagata cgccgtcaag gtacttttca aaggttgaca ttcaccgttg
    29101 cgacgcgaca acgggcatga ttcaatcatg tttttacaga cataagggta acgtgtagtg
    29161 gctcgtccga agagtgaaga caaaaaacaa gcattactgg aagcggcaac ccaggcgata
    29221 gcgcaatccg gtatcgccgc ctcaacggcg gtgattgcgc gtaacgcagg tattgcagaa
    29281 ggaacattat ttcgctattt cgcgaccaaa gatgagctga ttaacacgtt gtatttgcat
    29341 ttaaagcaga acctctgcca gtcaatgata atggagctgg atcgatccat taccgatgcc
    29401 aaaacgatga cccgctttat ctggaacagt tatatcagtt ggggtctgaa ccatcccgcg
    29461 cgccatcggg cgatccgtca actggccgtc agcgaaaaga tcaccaaaga gacggaacaa
    29521 cgggccgacg atatgttccc cgaattgcgc gatttatgtc atcgttccgt tttgatggta
    29581 tttatgtcgg atgagtaccg cgccttcggc gacggccttt ttctggcgct ggctgaaaca
    29641 acaatggatt tcgccgcgcg cgatcccgct cgcgctggcg aatatattgc gctgggattc
    29701 gaagccatgt ggcgcgcgct gactcgcgag gagcaataat ggacggtcaa acactgcacg
    29761 cctgtgcaaa acgctttgcg ctggaactgc cttttaccga acactgctgg cctttcggcc
    29821 cacagtacga tgtgtttaaa gtcggcggca aaatattcat gctgttcact gaacatcact
    29881 gtcgcccagt ggtgaacctg aagtcggccc cccaaaaatc cctggtgaat caacaaattt
    29941 accccagcat tgcgcctggc tatcacatga ataagaaaca ctggatttca gtctatgcgg
    30001 gcgaggatat caccgtctcg ctactcaacg atttgataaa tgactcatgg aatctggtcg
    30061 tagacgggct gcctaaaaga gagcaactgc gcctgcgacc gcgctgatgc aataaccgtt
    30121 tccgcatttt cctcccttat ctttttaccg ataacccggt accctgctga tacaaaaggg
    30181 tactaaacca accaggagca tttatggata tcgtttctgt cgccttaaag cgctactcca
    30241 ctaaggcgtt cgatcccagc aaaaaactga ccgccgaaga agcggataaa gtaaaaacac
    30301 tactacagta cagcccctcc agcaccaatt cccagccgtg gcactttatt gtcgccagta
    30361 cggaagaagg caaagcgcgt gtcgcaaaat ccgctgccgg aaactacacg ttcaacgaac
    30421 gcaaaatgct ggacgcctcc catgtggtgg tcttctgcgc caaaaccgca atggatgacg
    30481 catggctgca acgggtggtc gatcaggaag atgctgatgg ccgtttcgct acgccggaag
    30541 ctaaagcggc aaatgataaa ggtcgccgct ttttcgctga tatgcaccgc gtctcgctga
    30601 aagatgacca ccagtggatg gcgaagcagg tttatctgaa cgtcggcaac tttctgctgg
    30661 gcgtcgccgc gatgggtctc gacgccgtcc ccattgaagg tttcgacgcc gaggtgctcg
    30721 acgctgaatt tggtctgaaa gaaaaaggct ataccagtct ggtcgtggtg ccagtcggcc
    30781 atcatagcat cgaggatttc aacgccgggc tgccaaaatc acgtctgccg cttgaaacca
    30841 cactgacgga agtctaatcc cctgcctaag ccggacgccc gtccggcttt tttcaccttt
    30901 ctgccaggtt ccccaatgat caatggcgcg aagtgccagg ttttacatcg ttagtgttaa
    30961 cttcctcttt caacctattg aaaataaatg atatttaaaa ctggcacgcc gtttgccata
    31021 tctggatacc ccctatctgg atgaaggaga aaacgggtga gacatgttta tgtagccagc
    31081 catggccctt ttgcccgcgg acttattaac agtctatcgc tgctgattgg cgacgaacac
    31141 ggcgtgacac cggtttgcgc ctacgatggc gatattgtgt caccacgggg ttggccctcc
    31201 ctggcgtgtc atcaaaatcg ggcgctaaac ccaacgttat aacgggtttg attgccatcg
    31261 cttaaccctg ccgtttgcgc cagcccggcg aaagcggaca ctgttgccga cagcggaaaa
    31321 tctgcgccaa tcgcgatatc aacccagttt ttatcctgcg ctttcccggc acggctaaac
    31381 gtcagcgcgg tcgatttaag gccgccgttc gccacatacg tatcatcgcc aaactgacgg
    31441 cgataattaa tctgcgccca ggaatgaatg atactgtggc gaagatccag acgccaaccc
    31501 acgctgccca tctgcgaatg ggcgttttgg tcgccaaaac gcattgatgt actggtattg
    31561 agcttctcgc tataaccatt aacgtggctg taatcccatg catattgcag catcggcccg
    31621 gtcgttaacc acggcatcat gacaaaatca taaccgctgg ttaacctcgc gccccacagc
    31681 cgaccgttgg tttcgccctc ttccacccgt cttagcgcac cgagcgtgat actgcgctga
    31741 atgttactga atttagcgga caggtagtgt aaatcgccat ccagccacgc ctgaccggcg
    31801 cgtaaatggc tgaatacggc ggcctgaaaa ccgcgggcgt cataacgata attatcgtca
    31861 ggatgttgct tatccagaga accggctatc agccctccca gcagtacctg ctcgttaagc
    31921 tgataatcga cgccaaccgt cagattatta tgattaccgt tcccgtcggc ctcattatta
    31981 tcataacgtt gatatccccc gctgtatccg ccgaacatgc ccagtgaacc aacaggattt
    32041 tccccctggc gaagctgctg ataacggctg tcaagcgtgg tacgactgcc ttgcgccatc
    32101 gactgaacgc tttggttcag atatgtcgcc tgtaccggcg cggcaatgat cgactgaata
    32161 tattgcgcaa taatggtatg gacctgcgga ccgggatgta aatgatcggc aaacagatag
    32221 tcctgcgacg cattaaatcc aggcattgcc gaggagcaca ccgaagcgga tacgcccggc
    32281 gggcaggcca tgcctacggt atttgtcaga ccaaacgcct gcgggttggc aagaatttcc
    32341 ttaaagaggc cgttgatatc ggcacgggct atattgccgc cgtgttgctc cagccccttc
    32401 tcttccatct gattataata atcggtcaga gctgacgcct gctctgccac cttttcatag
    32461 cccgccagca gttgctcaac gagcagttgc tgaataaacg gattgctgct taccgttgca
    32521 gccgccgcca gcaacgcctt gcggatcgcc tgttgccgac tggcgaaatc gggcgtagct
    32581 ccctccgcca gcgcctctaa cgccgctttt agcgccgggg gcgccgctgc gcccagcccg
    32641 gcggtgatta ccgcctccag aagctctggc gtcgcactaa tatccggtac gtttggcacc
    32701 acgaccagcc cggcgccggc atccagtaac agccctacct gcgccgccgc gctagtggcg
    32761 ctattaccgg ctatttgctg tgccatggca ggtcgcgcga tggccgccgc cagatcgttt
    32821 ccgccgaccc agtgaatata caaaccgttg tggtcggctt ttccccccgt attggcaagc
    32881 cactgccgta cctgatccgc ggtattatcc tgcgggttta attccggggc cgtcatcgcg
    32941 ccgccagcgg cataattaga accgccattg ctggaagggc ttaatgccag cccatatcgt
    33001 tcggccaact gttcgtcgta gagcttattt tgaccactat cccaggtcca gcgaccgtta
    33061 tttccggtat cgctaaggct atcgccaatc accgtaagag agtcaaacgc acaggcagat
    33121 aatggcgcgg ccagcgccag cgagagtatg ccgtatttta gcagggtacg cttttgggtc
    33181 atccgatgtt ccttaatgtt attgttgata ggtacgacgg ttctaatcat tatccgacag
    33241 agatattgca atcgttttaa acattctggt taaaaagttt tcattcattg ttgacggact
    33301 ggcgcctgtt caaaaagagg gaaccgcgta aaataacgac gtttataggg cgctggataa
    33361 aatatagcgt atggataacc ccagaggcgc ttttacccgt ctgttgctga ttatgcctga
    33421 agcgcaggcg tcctgatttg cataaatgcc attcagcagt catcataggc tgctgtttat
    33481 aaaggagaga ttatgcagga attgatatcc caggtagaag atttagcggg aattgaaatg
    33541 aatcacacca cgtcgctggt ggtgatattt ggtattattt ttctgacagc agttgtcgtg
    33601 catattattt tgcactggat agtactgcgc gcttttgaaa aacgtgccag cgccagttcc
    33661 cgcctgtggc tgcaaattat tacccagaat aaattattcc atcgtctggc ttttacgcta
    33721 caaagcatca ttgtcaatat tcaagccgcg ctctggctac aaaaaggcag tgaggctgcg
    33781 gatatcctga cgacctgcgc gcagttatgg attatgacct acgccctgct gtcgttattt
    33841 tcgctgctgg acgtgatttt caatctatcg caaaaatggc ccgccgcctc tcagttaccg
    33901 ctaaaaggaa tatttcaggg cattaagctc atcggcgcaa ttatcgtcgg cattctgatg
    33961 atctcactgc tgattggcca gtcaccagca attttaatca gcgggctggg cgcgatggcc
    34021 gcggtattaa tgctggtctt taaagacccg attcttggcc tggttgctgg tatacagctt
    34081 tccgccaacg atatgctcaa actgggcgac tggctggaga tgccaaaata tggcgcagat
    34141 ggcgcggtca ttgatattgg cttaaccacg gtaaaagtac gcaactggga taataccatc
    34201 accaccattc ccacctggtc gctggtttcc gactcgttca aaaactggag cggcatgtct
    34261 gcgtccggcg gacgccggat taaacgcagc attaatattg acgcgaccag tatccatttt
    34321 ctggatgatg atgaaaaaca gcggctgtta accgcgcaac tgttaaagcc gtaccttacc
    34381 agccgtcatc aggaaatcga tgaatggaat aaacaactgg atgcgccgga atcagcctta
    34441 aatcaccgcc gaatgaccaa tatcgggaca tttcgcgcct atctgaacga atatttacgc
    34501 caccatccgc gcatccgtaa agacatgacg ctgatggtac gccaactggc gcctgacgat
    34561 catggtttgc cgatagagat ctacgccttt accaataccg tcgtgtggct ggaatatgag
    34621 agcattcagg ccgatatttt cgaccatatt tttgccgtgg tggaagagtt cggcttgcgt
    34681 attcatcaga cgccgaccgg cagcgatatt cgcgcgctgt cagggacatt gcgccattaa
    34741 tggattgccc gatcgcatga gcatgggatc gggcaaaaaa gttaatgagc cttacggcgc
    34801 aaaacggtaa acgcgataaa cagaaataca atccataccg gcagcaaaat cgccgacaat
    34861 cgcatatcgt ccatcgtaca cattaacacc agaatcagcg ccagaaacgc aatgcacaaa
    34921 tagtttccgg cgggatagaa cagcgcctta aattgcgtct cgcgcccttt acgacgcatc
    34981 gccgcgcgaa aacgtaaatg cgcgagacag atcattatcc agtttagcaa tagcgtcgcg
    35041 acaaccagcg ccatcaacag gctaaacgct ttttgcggca acagatagtt gatcagcacc
    35101 accagcgagg taatcgctcc ggacagcatc agcgagttca ccggcacgcc gcgatggctg
    35161 acgcgagtta aaaatttcgg cgcgttgcct tgtacggaca ggccgaacag cattcggcta
    35221 ttcgaataaa cgccgctgtt atacaccgaa agcgacgcga ccaggataac gaaattcagc
    35281 gccgaagcca ccacattact gtccaggtta tggaagatca tcacaaaagg gctgctattg
    35341 gatttcacct ctacccatgg atagagcgcc agcaacacca ccagcgaacc gatgtagaac
    35401 agcaaaatac ggtataccac ctgattcacc gctttcggga tgcttttttg cggatcgcgc
    35461 gcttccgccg cagtaatgcc gatcagctcc agtccgccaa aagaaaacat aatcaccgcc
    35521 agcgacagaa gcaaaccatg ccaaccggta gcgaagaaac cgttataacg ccagaggtta
    35581 tcaatgctgg catgttcgcc gccgtggccg gagaacagca gccacagacc aaaacctatc
    35641 atgccgataa tcgccagcac tttaatgagc gcgaaccaga attccgtttc gccatacaga
    35701 cgaacgttca ccagattcac ggcattaatg ataataaaaa acaccgccgc ccatacccat
    35761 gttggtacgt caggcagcca gtactgcata tagatgcccg ccgcggtcag ctccgccatc
    35821 ccgaccagca caaacatgac ccaatagttc cagcccgaca aaaagcccgc aaacggcccc
    35881 caatatttcc aggcgaagtg ggcaaacgat ccggaaaccg gctcttccac gaccatttca
    35941 cccaactggc gcataatgag aaaagcgata atcccggcaa cgccatagcc caacaaaaca
    36001 gccggccccg ccatttgaat cgccgggccg atgcccagaa acagtccggt gccaatggcg
    36061 ccgcccaggg cgattagctg aatatggcgg ttttgcaacc cccgttgaag cgtcggttca
    36121 ttcttcgacg cggcatccga cacgctggcg ccggatgcag ttgacgcgtt tttcacgtcc
    36181 tacccctgta tcgtttttat tgaggggcac cttttaacat ttcgctctcg ctgccgcaag
    36241 gcgcaatcgt ttgtcaaggc tcaactccgg acgttaacgt tatcgtgtaa aaaaagatgt
    36301 cgcggggagt aaaaagaaaa gagtacgcgc cgatatagaa cgttacgggt gacagacgcc
    36361 gggtataaaa tatgtgaata actctggacg aaaagtacga caccctacag aatacattta
    36421 gtattttttc agtattttca aaaaggtgaa tcagacctgg tatctgttat ccatttttga
    36481 gccacgccag gcgtcaacgt catgaataag atcatcaaac gtttagagat cattaaaagc
    36541 gccatcgaac ttgaggacga agagattatc cgtcagcagc tcatctacct gaaaaatgag
    36601 ccgcaggatg ccgtaatcag cgcgattgcc caggcgattg aaactcgtcg attcagtgac
    36661 gccatgcaag agatcgccgc ctggctacag gctcaacggg cgctctcgac gtggcaagat
    36721 ccctctattg ccgccagtaa actggagctg aaagcgcttg aagcccaact tcgcgatctg
    36781 attgacaaac gaaatgcgcg ggtacaaatc ctcgacgatt tcaacgacct ctatcatctg
    36841 cgtctcgggc cgttgatgag ccgtattctg gagttgcgta aacagctcgc ggtgagtatg
    36901 cagcgtaagc aagaggccga aataaaacgc cgggaaaagg attatcaatc ctgcctgcaa
    36961 tttatttccc aggccgtgga tcaactggca acgctaaaac agcagtggac aggattgaat
    37021 gccgcctcgc gcgaagcggt gggcatccgt cagcgaatcc agcagcagac ggaattaatc
    37081 accgcgttgc tggcggaaat tcgcgagctg gaagcggatt tttcccatca ggacgacagc
    37141 gcattccgcc aggcgcagga aaatgcggaa cagaactatc accagtaccg ggagcagcag
    37201 caggaagcgt aattccgcta cgcccgcgat caacgtttgt cggcagacga acgcagtgaa
    37261 ttaaaacgtt tgtggcgtca ggccagccgc ctgtgtcacc cggatgtggt cgccgatgaa
    37321 ttgaaagaaa aagcgcacca gatgatggta cagcttaatc aggcgcggca gaatgccgat
    37381 ctggcggcaa ttcgcgcgtt attgacgcag ctgcaaagcg gtctggaacc gatgatggca
    37441 agcgacaggc taaataacct ggaacatctg cgccataaaa tacgccagct ccgcacgcaa
    37501 atcgacgcgc tgttgaaaga gataacgcag ctggaaacgg aaaatgcctg gcggctcgcc
    37561 tcttccgttg cgaataagga agcctatttc tccgagcagg aacgggcgct aaccgaaatt
    37621 cgcaatacgc tggaggcgca ggttcaacag gtggaacagg aacttctggc agggtagtcc
    37681 atcattcatc aacacattgt cggatggcgc aagcgccacc cgacgaatcg cggcataaag
    37741 agagtaagag ggtcgctact ggcgctgtaa aagtaacgaa cgggcggagt ccgccatgat
    37801 catcaccgca cctgccagca ttaacgtatc ttttaatacc agccgcccgg cgcccgataa
    37861 atacgggaaa ccataatgcg catcgcccag cggcataacc caggcctccg gcgtggtgat
    37921 taaaaacgac agcgtgacaa atggcgtcag gaatgccagc acgccgcccg ccagccctaa
    37981 ccagcggcta acagggttag ccagtaccag cgccgcgata atcaattcca ccacgcccag
    38041 accatccgaa aacgcatacg tattattggc cgtttgccag gcgcgttcct ccggttttag
    38101 ttcgccctca tgagtcagat gctgacgata ttcttcagga tgttcataga aaaaagacat
    38161 aaacgggctg ttcgccacaa acggggtaat actgtctgcc tcatagggca caaattttag
    38221 tagtccaatc cagataaaaa cgatggcgat actcaggcga attaatgtta atcccagccg
    38281 atccccctga cttaacagac gaagatattt atccatctca ggctctcctt atttatataa
    38341 tatcgcagtg gcgtaacccg tattatcaat acgcattgac gtaattttcc atgacgacgc
    38401 ctgtttactt tgcgccagtc tggcaatagc gtcttcaagc attgacggtg ttgctgacac
    38461 cgcagaaacg ctgatatatt caacgtcagt tagcggctgg gcggaggcgg aaaacgccag
    38521 cggcgcagcc aataatgaag caataagtgt ggtaactttt aacatcgaga tttccagtcg
    38581 tgggttattt caatggtgtt ataatacgtt atgcctgact aaagcctttt ctttcagacg
    38641 ccagcatatt tgtcctgtcg tatttttatg gtctgacagg caaaaaaaag ccctgattaa
    38701 cagggctaca ttatttatgt tttacttaat gagagagaag agatcgttta aagactcact
    38761 cattgtagga tgggtaaata tctggtcgcg taacaccgta taaggtaaat ctgcatccat
    38821 aacggtttta acgatattaa tcatttcatg agaatcgacg cataacaatg acacccctac
    38881 aatacgctgc gtattcacgt ccactaccgc ttttagtacg ccacgggtat cattcataac
    38941 acgggcgcga gggatcgccg ccaccggtaa tgtcaccacc tgcaccgttg cgccgcttgc
    39001 ccgcgcttgt tcttccgtca gcccgacacg agagagcggc ggcgtcataa agacggaata
    39061 cggtacgttc tggcgatcgc gggtactgcg tttgccatct cccaataacc cgtcgcgtac
    39121 aatacgaaaa tcatccagtg aaatataggt aaactgcaac ccaccggtaa catcgcccat
    39181 cgcccagata ttgtccgccg tggtacgcag gtaatcatcc acgatgatcc cgccgcgttc
    39241 gttcaccgcc acaccggcgt tctgcaactg taagccagcc gtcgccggtt ttcgccccga
    39301 cgccaccagc agggcatcca caagatgcgc gccttccggc gtttcaactt gtaccgcgcc
    39361 ctccgttgag gatacggcct gtacgttggc gtttaaaatt agctcgacgc ccttttcctg
    39421 taaaatgtgg gtaattgcct gcgcgatatc ccgatcttca cgaggcaaga attgcggcgc
    39481 tgcttcaaag atagtgacct tcgtaccgaa gttagcgaac attgaggcaa attcaaggcc
    39541 aatataaccg ccgcctaaaa tccccagccg cgccggacgc tggctcaggc ttagtagccc
    39601 ggtgctatcg aacacccctg ccgtcgttgt taagcccgta atagccggga tcaccgactc
    39661 tgcgccagta ttaatgaaga tcttttctcc ccgtaacacc cgctcgccgt ccgcctgaaa
    39721 tacccgtaag gtatggttat caataaactc cgcccttccc tcaatcacat cgacattgtc
    39781 caggtcggca agattatgaa aatttttgtc gcgtaaaaaa tttacgaccg ccgctttgcg
    39841 ttgcatggcg acagaaaaat cgccctcacg ttccgcgtca tacaccagcg ttttcgttgg
    39901 aatacagcca atgttgatac aggttccgcc aaacatactg gcggactgtt cgataatcgc
    39961 cacgcgccat cccgtcttcg ccagagttgc cgccaacgtt tttcctgcct tgccaaaacc
    40021 aataatgagc gcctgatact gtgtcatctt ctttctccgc caaatcacca tctgtttgtc
    40081 aggacaagta taaataacgt caaaaaagac agggttatcc gtaacgcgtc attttttgtc
    40141 ttatcgtcta aattagcggt taggaaaaac aaggatagaa atgacattga gtccgaaata
    40201 tagtgatcag agacagaaat ggttatcctt atttttgaaa ataaatctgt tctggagtct
    40261 atatggatgc gcttagtcgg ctattgacgc ttaacgcccc tcagggctca atcgacaaga
    40321 attgcccgtt aggcggcgac tggcagttgc cgcacgccgc tggcgagcta tcggtgattc
    40381 gctggcatac cgttacgcag ggcgaagcgc aactggaaat gcctaccggc gacgccatga
    40441 cgcttacgcc gggaaaggtg gtgattctgc cgcaaaactc cgcccaccgt ttgcgccagt
    40501 ctggcgaagc accgacacat atcgtgtgcg gtagtctacg tctgcacacg acgtcacgtt
    40561 atttccttac cgcgttgccg gaagtgttat gtcttgcccc gccgccgcat agccccgcca
    40621 gtatctggct taacgccgcc atttcgctgt tacagcagga gtcagaacgc catttacctg
    40681 gcgctgatgt cttatacagt cagcagtgcg ccacgttgtt taccctcgcc attcgcgact
    40741 ggctatcgca ggctggcacg gcgaaaagcg tgctcaattt attgctgcat ccccggctgg
    40801 gccgcgtgat cctgcacatg ctggaaacac cggcgcatcc ctggacggtc gaaacgctgg
    40861 tgcaacgggt acacatgtcg cgggcgagct tcgcccagct atttcgcgac gtgtccgcta
    40921 caacgccctt agccgtgtta acaacgctgc gcctgcaaat cgccgcccag accctgtcgc
    40981 gtgaagcgct gccggtgatg gtgattgccg agtcggtagg ttatgcgagc gaatcttctt
    41041 ttcacaaagc gtttgtccgt gaattcggtt gtacaccagg cgagtaccgc aaacgggtca
    41101 acgcgcttgg acgataaacg tatactgaac ccgcctacag tttgacgccg caggcgggcg
    41161 acacacatta tgccgcaagg cgacgatgcc tgcgcagcca catcagcttg taggctgccg
    41221 gaatgatgaa cagcgacagc agcggcgcgg taatcatgcc gccaatcatc ggcgtggcaa
    41281 tacggctcat cacctcagaa cccgcgcctt ttcgatcgtt tttatcgcgt tgctccctcc
    41341 cgccagcgta aaggggaagg ccgcggtata ggcctggcaa ttgtaaaatc catcgtcatt
    41401 gcgcatcagg gaaaagtttc tgtcacctcc gatacgcgct actcgtttta ttttgacatt
    41461 acccaaacac ctccgttgaa ctgtagcgat agtgaaaggc gctatcacta gccagcaaaa
    41521 taatctgata taatcgtcat tatcccgtca cgcgccaaac ccaacaactg ttttattatt
    41581 tctcttatta acccacaccg gagaaataag ataaataagt ttacatccct tttagctgtc
    41641 gtttttattt cagctggcgt acacaccgca gagaaaatgg aatcccgcca attatccgct
    41701 acagcacatg agatgatgaa taacggtgac gccttcgcgc atcagcaaat ggctcagaca
    41761 cagaaaccca gcgccccgac tactgtggaa aatgcgacac ccttttctga aatggacgac
    41821 tatgaaaaag caatggtcat ccatcaatcg atgaataatg cccattcttt ctcccacgag
    41881 atccaggctg aggagcacca taaacagatt aaacgcaatt agttatttgc atattagcgt
    41941 cacgtactgc ggatggcaca acgtcgcccc cgcagaagct tacggattaa cataattttg
    42001 agaggttaaa tggcgcgccc tgcaggattc gaacctgcga cccacggctt agatgttcct
    42061 ggaactacct gagctaacaa caagttatcc cattaccacg gcgctcactc gccccatctt
    42121 cgaaaaacat gcaaagcttt gtgtgtcccg tttttgtccc aacccactca gcaatcagca
    42181 gctccaattg atcggtaaca acgatcaatt aataagacaa caataagttc aagctatcaa
    42241 atataacatt attgatcgtt tatatcgaaa aaagcaattt gtagtactat actccagacc
    42301 tttccgaatc cgctgatttt cataatgttg aagttattcg ctaagtacac atcgatcggt
    42361 gttcttaaca cgcttattca ttggggcgta tttgcttttt gtgtgtatgg gatgcatacg
    42421 catcaggcgc tggcgaactt ttccggtttt gttatcgccg tatcgttcag cttctatgcc
    42481 aatgcgcgct tcacctttaa cgccagcacc accacgcttc gctacatgat gtacgtggga
    42541 tttatgggaa cactgagcgc cgttgttggc tggatggctg acaaatgttc cctgccgcca
    42601 ctccttactc ttgtcacctt ttcagctatc agcctgatat gcggattcat ttattcaaag
    42661 ttcattgtct ttagggatgc gaaatgaaaa tctcattagt cgttccggtc ttcaatgaag
    42721 aagccacgat acctattttc tataaaacgg ttcgcgagtt tgaagagtta aaaccgtatg
    42781 aagttgagat tgttttcatc aacgacggaa gcaaagatgc gactgaatca ataattaaca
    42841 aaatagctgc atctgatccg ctcgttattc cgctttcgtt tacgcgaaac ttcggtaaag
    42901 aacctgctct tttcgcgggt ctcgaccatg caaccgggga tgcggtcatt cctattgatg
    42961 tcgatttaca ggatccgata gaagttatcc cccatctcat tgagaagtgg caggctggcg
    43021 cggatatggt gctggctaag cgctcagacc gctcaactga cgggcgcatg aagcgtaaga
    43081 cagctgaatg gttttataag ctgcataata aaatcagcaa tccgaaaatt gaagagaacg
    43141 tcggtgattt ccggttaatg agccgtgatg ttgtcgaaaa tattaaacag atgccagaac
    43201 gtaatctgtt tatgaaaggc gttctgtcat gggtgggcgg caagactgat gtagttggat
    43261 acgcccgcgc tgagcgtgtt gccggcgatt caaaattcaa tggctggaaa ttatggaatc
    43321 tggcgctgga aggaataact tctttctcaa catttccgct ccgcatatgg acgtacattg
    43381 gattgtttat tgcaggtatg tcgttccttt acggtacatg gatgattata gataaattaa
    43441 tatttggaaa taatgttcct ggctacccgt ctcttcttgt ttctgtactt ttcctgggtg
    43501 gcgttcaatt gataggaata ggtattcttg gggaatatat tggcaggatt tacatagaaa
    43561 ctaaaaaaag gcctaaatac ataattaaga atgggaagaa aaatggttaa caatagatta
    43621 aaaat
//
LOCUS       DAJVBX010000012        42191 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.012, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000012 DAJVBX010000000
VERSION     DAJVBX010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 42191)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42191)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42191
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.012"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            353..1252
                     /locus_tag="OPV72_000604"
     CDS             353..1252
                     /locus_tag="OPV72_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCR9912986.1"
                     /translation="MDKIYAMKLFVRVAERESFSRAAEDIGLPKGSVSRQIQALEHQL
                     GIRLLHRTTRRVQLTQDGMVYYERAKDLLSNLDELEGLFQPDPASISGKIRVDIPPGL
                     ANSLIMPRLLTFLHQYPGIALELCSSDRQVDLLREDFDCVVRTEPLHAPGILTRPLGK
                     LRRVNCASPQYLARFGYPENLDDLASHAMVHYSLTPGVSSPGFAFETPHGMQWVKTGG
                     MLTVNSTETWHTACLAGLGIIQTPRIAVREALRAGALIEILPQYRAAPLPVTLHYPHR
                     RNLSRRVHLFMVWLTETIKEAAE"
     gene            1325..2353
                     /gene="yhjD"
                     /locus_tag="OPV72_000605"
     CDS             1325..2353
                     /gene="yhjD"
                     /locus_tag="OPV72_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane protein YhjD"
                     /protein_id="HCR9912987.1"
                     /translation="MTQENDVKRPIQELEHDPIQKIETQPHDAPEKNEKANQALHSVT
                     TLMQKIQRQPMVAHLIRATERFNDRLGNQFGAAITYFSFLSMIPIMMVSFAAAGFILA
                     SHPNLLEDIFSKILMNVSDPTLASTLKNTINTAVQQRTTVGLVGLGIALYSGVNWMGN
                     LREAIRAQSRDVWERKPQDQEKIWLKYLRDFISLIGLLIALIITLSITSIAGSAQQMI
                     ISALYLDSIEWLKPAWHLIGLAISIFANYLLFFWIFWRLPRHRPRKKALIRGTFIAAI
                     GFEVIKIIMTYTLPSLVKSPSGAAFGSVLGLMAFFYFFARLTLFCAAWIATAEYKDDP
                     RMPGKTQR"
     gene            2704..4026
                     /locus_tag="OPV72_000606"
     CDS             2704..4026
                     /locus_tag="OPV72_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MHS family MFS transporter"
                     /protein_id="HCR9912988.1"
                     /translation="MQATATTLDHEQEHVPVNSRNKVVIASLIGTAIEFFDFYIYATA
                     AVIVFPLIFFPQGDPTAATLQSLATFAIAFVARPIGSALFGHFGDRVGRKVTLVASLL
                     TMGISTVIIGLLPGYATIGIFAPLLLALARFGQGLGLGGEWGGAALLATENAPPRKRA
                     LYGSFPQLGAPIGFFFANGTFPLLSWLLTDEQFMSWGWRVPFIFSAVLVIIGLYVRVS
                     LHETPVFAKVAAAKKQVKIPLGTLLTKHVHVTILGTFIMLATYTLFYIMTVYSMTYST
                     AAAPVGLGLPRNEILWMLMMAVIGFGVMVPVAGLLADAFGRRKSMVIITTLIILFALF
                     AFTPLLGSGNPALVFVFLLLGLSLMGLTFGPMGALLPELFPTEVRYTGASFSYNVSSI
                     LGASVAPYIAAWLQSHYGLAAVGVYLASMAALTLIALLLTHETRHQAL"
     gene            complement(4066..6126)
                     /locus_tag="OPV72_000607"
     CDS             complement(4066..6126)
                     /locus_tag="OPV72_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AsmA family protein"
                     /protein_id="HCR9912989.1"
                     /translation="MTKAGKITAAITGTFLLLIAIVILLIATFDWNRLKPTINQKVST
                     ELNRPFAIRGDLGVVWERQKQESGWRSWVPWPHVHAEDVILGNPPDIPEVTMVHLPRV
                     EATLAPLALLTKTVWLPWIKLVKPDARLIRLSEKTNNWTFNLAQDKNTDPNAKPSAWS
                     FRLDNILFDQGRIAIDDKVSKADITILVDPLGKPLPFSEVTGTKGKADKSTVGDYVFG
                     LKAQGRYNGEPLTGTGKIGGMLALRSESTPFPVQADFRSGNTRVAFSGVVNEPMKMGG
                     VDLRLKFSGDSLGDLYDLTGVLLPDTPPFETDGRLVAKIDAEKSSVFNYRGFNGRIGD
                     SDIHGTFTYTTGKPSPKLEGDVESRQLRLADLGPLIGVDSGKDAEQSKRSEQRKGEKN
                     VQPADKVLPYDRFETDKWDVMDADVRFKGRRIEHGGSLPISDLSTHIILKNADLRLQP
                     LKFGLAGGSIVSNIHLEGDKKPMQGRADIQARRLKLKELMPDVELMQKTLGELNGDAD
                     IRGTGNSVAALLGNSNGNLKLLMNDGLISRNLMEIVGLNVGNYIIGQIFGDDEVRVNC
                     AAANLNIANGVARPQIFAFDTENALINVTGTASFASEQLDLTIDPESKGIRIITLRSP
                     LYVRGTFKNPQAGVKPGPLIARGAVAAALATLVTPAAALLALISPSEGEANQCRTILT
                     QMKQ"
     gene            complement(6236..7003)
                     /gene="pdeH"
                     /locus_tag="OPV72_000608"
     CDS             complement(6236..7003)
                     /gene="pdeH"
                     /locus_tag="OPV72_000608"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-guanylate-specific phosphodiesterase"
                     /protein_id="HCR9912990.1"
                     /translation="MIKQVIQQLRVPDAGIENLQERRYWLQCERAYTYQPIYQTDGRL
                     MTVELLTAVTHPDNPSRRIAPDRYFAELAVRHRIDVVKEQLHQLEQKADFFTRHRLLA
                     SVNVDGPTLIAMRQQPDILAAMERLPWLRFELVEHIRLPKDSSFASMCEFVPLWLDDF
                     GTGMANFSALSEVRYDYIKVARELFVMLRQSPEGRNLFILLLQLMNRYCRGVIVEGVE
                     TLEEWRDVQRSPAFAAQGYFLSRPVPLISLEEVILTL"
     gene            7232..8161
                     /locus_tag="OPV72_000609"
     CDS             7232..8161
                     /locus_tag="OPV72_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HCR9912991.1"
                     /translation="MSKKIAVIGECMIELSQKGADVQRGFGGDTLNTSVYIARQVDSA
                     ALAVHYVTALGTDSFSQQMLEAWQHENVDTSLTQRMENRLPGLYYIETDDTGERTFYY
                     WRNEAAAKFWLESEQSAAICETLATFDYLYLSGISLAILSPTSRDKLLSLLRECRANG
                     GKVIFDNNYRPRLWTSREETQQVYQKMLECTDIAFLTLDDEDALWGKQPVEEVIARTH
                     AAGVQEVVVKRGADSCLVSIQGEALIDVPAVKLPKEKVIDTTAAGDSFSAGYLAVRLT
                     GGSATDAAKRGHLTASTVIQYRGAIIPHDAMPQ"
     gene            complement(8215..9702)
                     /locus_tag="OPV72_000610"
     CDS             complement(8215..9702)
                     /locus_tag="OPV72_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HCR9912992.1"
                     /translation="MQGTKIRLLAGSLLMLASAGYVQADALQPDPAWQQGTLANGLQW
                     QVLATPQRPSDRIEVRLQVNTGSLTESTQQSGFSHAIPRIALTQSGGLDAAQARSLWQ
                     QGFDPKRPMPPVIVSYDSTLYSLSLPNNRNDLLKEALTYLANVSGKLTITPETVNHAL
                     SSEDMVATWPADTKEGWWRYRLKGSALLGHDPAEPLKQPVDAAKIQAFYEKWYTPDAM
                     TLIVVGNIDARSVAEQINKTFGTLKGKRETPAPVPTLSPLRAESVSIMTDAVRQDRLS
                     IMWDTPWQPIRESAALLRYWQADLAREALFWHIQQELTKNNAKDIGLGFDCRVLFLRA
                     QCAINIESPNDKLNTNLSLVANELAKVRDKGLSEEEFTALVAQKNLELQKLFATYART
                     DTDILTGQRMRSLQNQVVDIAPEQYQKLRQNFLNSLTVDMLNQNLRQQLSQEMALILL
                     QPQGEPEFNMKALKATWDEIMVPATAAAVEADEAHPEVTETPAAQ"
     gene            complement(9922..11208)
                     /gene="dctA"
                     /locus_tag="OPV72_000611"
     CDS             complement(9922..11208)
                     /gene="dctA"
                     /locus_tag="OPV72_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C4-dicarboxylate transporter DctC"
                     /protein_id="HCR9912993.1"
                     /translation="MKTSLFKSLYFQVLTAIAIGILLGHYYPELGAQMKPLGDAFVKL
                     IKMIIAPVIFCTVVTGIAGMESMKAVGRTGAVALLYFEIVSTIALINGLIIVNVVQPG
                     AGMNVDPATLDAQAVAVYAAQAKEQGIIAFLMDVIPGSVIGAFASGNILQVLLFAVLF
                     GFALHRLGSKGQLIFNVIESFSQVIFGIINMIMRLAPIGAFGAMAFTIGKYGVGSLVQ
                     LGQLIICFYITCILFVVVVLGTIARVTGFSIFKFIRYIREELLIVLGTSSSESALPRM
                     LDKMEKLGCRKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNSHMDIFHQITLLV
                     VLLLSSKGAAGVTGSGFIVLAATISAVGHLPVAGLALILGIDRFMSEARALTNLVGNG
                     VATVVVAKWVKELDHQKLDDVLNNRAPDGKTHEISS"
     gene            complement(11366..13372)
                     /gene="hmsP"
                     /locus_tag="OPV72_000612"
     CDS             complement(11366..13372)
                     /gene="hmsP"
                     /locus_tag="OPV72_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm formation regulator HmsP"
                     /protein_id="HCR9912994.1"
                     /translation="MRVSRSLTIKQMAMVAAVVMVFVFVFCTVLLFHLVQQNRYNTAT
                     QLESIARSVREPLSSAILKADLPGAETILESIKPAGVVSRADVVLPNQFQALRKRFIP
                     ERPVPVMVTRLFELPVQISLPVYSLERPANPQPLAYLVLQADSYRMYKFVMSALSTLV
                     TIYLLLSLILTVAIAWCVNRLIVHPLRKIARELNDIPQQELIGHQLALPRLHQDDEIG
                     MLVRSYNLNQQLMQRQREEQTDNAMRFPVSELPNKAFLMALLEQVITRQQTTALIIVT
                     CETLRDTAGVLQETQREILLLTLVEKLKSVLAPRMVLTQVSGYDFAIIAHGVKEPWHA
                     ITLGQQILTIINERLPIQGIQLRPSCSIGIAMYYGDLTAEALYGRAVSAAFTARRKGK
                     NQIQFFDPAQMEAAQQRLTEESDILTALDNHQFAIWLQPQVEMRSGNVLSAEALLRMQ
                     QPDGSWELPEGLIERIESCGLMVTVGHWVLEESCRQLAAWQERGVTLPLSVNLSALQL
                     MHPGMVSDLLELLNRYRIQPGTLILEVTESRRIDDPHAAVAILRPLRNAGVRIALDDF
                     GMGYAGLRQLQHMKSLPVDILKIDKMFVDGLPDDHSMVTAIILMARSLNLQLIAEGVE
                     DEAQRAWLEQAGVNVAQGFLFARPVPADIFEERYLSHENPDYKS"
     gene            complement(13546..17089)
                     /gene="bcsC"
                     /locus_tag="OPV72_000613"
                     /pseudo
     CDS             complement(13546..17089)
                     /gene="bcsC"
                     /locus_tag="OPV72_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462517.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsC"
     gene            complement(17071..18173)
                     /gene="bcsZ"
                     /locus_tag="OPV72_000614"
                     /pseudo
     CDS             complement(17071..18173)
                     /gene="bcsZ"
                     /locus_tag="OPV72_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012219336.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cellulase"
     gene            complement(18180..20480)
                     /gene="bcsB"
                     /locus_tag="OPV72_000615"
     CDS             complement(18180..20480)
                     /gene="bcsB"
                     /locus_tag="OPV72_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis cyclic di-GMP-binding
                     regulatory protein BcsB"
                     /protein_id="HCR9912995.1"
                     /translation="MKRKLSWMCAAVIGLSAFPAFMTAAAPAMPPLINAEPTEPAQSP
                     VTEAPVVAQTAPSREVKLTFAQIAPPPGSMALRGVNPNGGIEFGMRSDEVASKAVLNL
                     EYTPSPSLLPVQSQLKVYLNDELMGVLPVTKEQLGKKTLAQVPINPLFITDFNRVRLE
                     FVGHYRDVCENPASSTLWLDIGRNSALDLTYNMLAVNNDLSHFPVPFFDPRDNRPVTL
                     PIVFADMPDLAQQQAASIVASWFGSRAGWRGQRFPVLYNHLPDRNAIVFATNDRRPDF
                     LRDHPAVNAPVIEMMNHPDNPYVKLLVVFGRDDKDLLQAAKGIAQGNILFRGSSVVVN
                     DVKPLLARKPYDAPNWVRTDRPVTFGELKTYEEQLQSSGLEPAPINVSLNLPPDLYLL
                     RSNGIDMDLNYRYTSPPTKDSSRLDISLNNQFLQAFSLNSTQETNRLLLRLPVLQGLL
                     DGKTDVSIPALKLGAMNQLRFDFRYMNPMPGGSVDNCITFQPVPNHVVIGDDSTIDFS
                     KYYHFIAMPDLRAFANAGFPFSRMADLSDTLAVMPKTPTEAQMETLLNTVGAIGGQTG
                     FPAINLTITDDSAQIADKDADLLIIGAIPGKLKDDKRIDLLVQATQSWVKTPMRQTAF
                     PSIMPDEADRAADAQSTVTASGPMAAVVGFQSPFNDQRSVIALLADSPRGYQLLNDAV
                     NDSGKRAAMFGSVAVIRESGVHSLRVGDIYYVGHLPWFERLWYALANHPVLLAVLAAL
                     SVVLLAWVLWRLLRILSRRRLDPDHE"
     gene            complement(20491..23115)
                     /gene="bcsA"
                     /locus_tag="OPV72_000616"
     CDS             complement(20491..23115)
                     /gene="bcsA"
                     /locus_tag="OPV72_000616"
                     /EC_number="2.4.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-forming cellulose synthase catalytic
                     subunit"
                     /protein_id="HCR9912996.1"
                     /translation="MSALSRWLLIPPVSARLSERYQGYRRHGASPFSAALGCLWTILA
                     WIVFPLEHPRWQRIRDGHKALYPHINAARPRPLDPARYLIQTLWLVMISSTKERHEPR
                     WRSFARLKDVRGRYHQWMDTLPERVRQKTTHLEKEKELGHLSNGARRFILGVIVTFSL
                     ILALICITQPFNPLSQFIFLLLLWGVALLVRRMPGRFSALMLIVLSLTVSCRYIWWRY
                     TSTLNWDDPVSLVCGLILLFAETYAWIVLVLGYFQVVWPLNRQPVPLPKEMSQWPTVD
                     IFVPTYNEDLNVVKNTIYASLGIDWPKDKLNIWILDDGGRESFRQFARHVGVHYIARA
                     THEHAKAGNINNALKHAKGEFVAIFDCDHVPTRSFLQMTMGWFLKEKQLAMMQTPHHF
                     FSPDPFERNLGRFRKTPNEGTLFYGLVQDGNDMWDATFFCGSCAVIRRKPLDEIGGIA
                     VETVTEDAHTSLRLHRRGYTSAYMRIPQSAGLATESLSAHIGQRIRWARGMVQIFRLD
                     NPLFGKGLKLAQRLCYLNAMFHFLSGIPRLIFLTAPLAFLLLHAYIIYAPALMIALFV
                     IPHMVHASLTNSKIQGKYRHSFWSEIYETVLAWYIAPPTLVALINPHKGKFNVTAKGG
                     LVEEKYVDWVISRPYIFLVLLNLLGVAAGVWRYYYGPENETLTVIVSLVWVFYNLVIL
                     GGAVAVSVESKQVRRAHRVEIAMPGAIAREDGHLFSCTVHDFSDGGLGIKINGQAQVL
                     EGQKVNLLLKRGQQEYVFPTQVVRVTGNEVGLQLMPLTTKQHIDFVQCTFARADTWAL
                     WQDSFPEDKPLESLLDILKLGFRGYRHLAEFAPPSVKVIFRSLTALIAWIVSFIPRRP
                     ERQAAIQPSDRVMAQAQQ"
     gene            complement(23112..23864)
                     /gene="bcsQ"
                     /locus_tag="OPV72_000617"
     CDS             complement(23112..23864)
                     /gene="bcsQ"
                     /locus_tag="OPV72_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsQ"
                     /protein_id="HCR9912997.1"
                     /translation="MAILGLQGVRGGVGTTSLTAALAWALQILGENVLVIDASPDNLL
                     RMSFNVDFVHQGGWARSLLDGQDWRDAGLRYTSQLDLLPFGQLTSQEWENPQAWQETL
                     GEIGSAIQALKASGRYSWILLDLPYGESPLTRQLVSLCDHTLAIAQVDANCHIRLHQQ
                     ALPAGAHILINDLRIGSQLQDDLYQVWLQSQRRLLPIVIHRDEAMAECMASKQPLGEY
                     RSDSLAAEEVLTLANWCLLHDAGDKTSAGSLR"
     gene            complement(23865..24068)
                     /locus_tag="OPV72_000618"
     CDS             complement(23865..24068)
                     /locus_tag="OPV72_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhjR family protein"
                     /protein_id="HCR9912998.1"
                     /translation="MYNNEPGAQSDPTLGYTFQNDFLALSQAFSLPEIDYTDISQREQ
                     LAAAIKRWPLLAEFAQPHSLRKP"
     gene            24313..25884
                     /gene="bcsE"
                     /locus_tag="OPV72_000619"
     CDS             24313..25884
                     /gene="bcsE"
                     /locus_tag="OPV72_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsE"
                     /protein_id="HCR9912999.1"
                     /translation="MRDTVDPVFSLGISSLWDELRHMPTGGVWWVNADRQQDAISLVN
                     QTIASQTENANVAVIGMEGDPGKVIKLDESHGPEKIRLFTMPDSEKGLYSLPHDLLCS
                     VNPTHYFFILICANNTWRNITSESLHKWLEKMNKWTRFHHCSLLVITPCNNSDKQSSL
                     LMGEYRSLFGLASLRFQGDQHLFDIAFWCNEKGVSARQQLLLCQQDERWTLSHQEETA
                     IQPRSDEKRILSHVAVLEGAPPLSEHWTLFDNNEALFNDARTAQAATIIFSLTQNNQI
                     EPLARRIHTLRRQRGSALKIVVRENIASLRATDERLLLGCGANMIIPWNAPLSRCLTL
                     IESVQGQQFSRYVPEDITTLLSMTQPLKLRGFQPWDTFCDAIHTMMSNTLLPADGKGV
                     LVALRPVPGIRVEQALTLCRPSRTGDIMTIGGNRLVLFLSFCRVNDLDTALNHIFPLP
                     TGDIFSNRMVWFEDKQISAELVQMRLLSPELWGTPLPLAKRADPVINAEHDGRIWRRI
                     PEPLRLLDDTAERAS"
     gene            25881..26072
                     /gene="bcsF"
                     /locus_tag="OPV72_000620"
     CDS             25881..26072
                     /gene="bcsF"
                     /locus_tag="OPV72_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsF"
                     /protein_id="HCR9913000.1"
                     /translation="MMTISDIVQIILFCALIFFPLGYLARHSLRRISDTTRLLFAKPR
                     YVKPAGTLRRATKVKADKK"
     gene            26069..27748
                     /gene="bcsG"
                     /locus_tag="OPV72_000621"
     CDS             26069..27748
                     /gene="bcsG"
                     /locus_tag="OPV72_000621"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsG"
                     /protein_id="HCR9913001.1"
                     /translation="MTQHTQTPSMPSPLWQYWRGLSGWNFYFLVKFGLLWAGYLNFHP
                     LLNLVFMAFLLMPIPKYRLHRLRHWIAIPVGFALFWHDTWLPGPQSIMSQGTQVAEFS
                     SGYLLDLIARFINWQMIGAIFVLLVAWLFLSQWIRVTVFVVAIMVWLNVLTLTGPVFT
                     LWPAGQPTDTVTTTGGNAAATVATAGDKPVIGDMPAQTAPPTTANLNAWLNTFYAAEE
                     KRKTTFPAQLPPDAQPFDLLVINICSLSWSDVEAAGLMSHPLWSHFDILFKHFNSGTS
                     YSGPAAIRLLRASCGQPSHTRLYQPANNECYLFDNLAKLGFTQHLMMDHNGEFGGFLK
                     EVRENGGMQSELMNQSGLPTALLSFDGSPVYDDLAVLNRWLTGEEREANSRSATFFNL
                     LPLHDGNHFPGVSKTADYKIRAQKLFDELDAFFTELEKSGRKVMVVVVPEHGGALKGD
                     RMQISGLRDIPSPSITNVPAGVKFFGMKAPHEGAPIDINQPSSYLAISELVVRAVDGK
                     LFTEDSVNWNKLTSNLPQTAPVSENANAVVIQYQGKPYVRLNGGDWVPYPQ"
     gene            complement(27830..27937)
                     /locus_tag="OPV72_000622"
     CDS             complement(27830..27937)
                     /locus_tag="OPV72_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin Ldr family
                     protein"
                     /protein_id="HCR9913002.1"
                     /translation="MTLTQLGVAFWHDLAAPIIAGIIASVIVNWLRDRK"
     gene            28065..28462
                     /locus_tag="OPV72_000623"
                     /pseudo
     CDS             28065..28462
                     /locus_tag="OPV72_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133841.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
     gene            28580..29878
                     /locus_tag="OPV72_000624"
     CDS             28580..29878
                     /locus_tag="OPV72_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HCR9913003.1"
                     /translation="MQDDTLPLNNSNATTTPLSTRLPFTKYDFGWVLLCIGMAIGAGT
                     VLMPVQIGLKGIWVFITAFIIAYPATYIVQDIYLKTLSESETCDDYTDIISHYLGKNW
                     GVFLGVIYFLMIIHGVFIYSLSVVFDSASYIKTFGLTEADLSQSIIYKVAIFAVLVAI
                     ASGGEKLLFKISGPMVVVKVGIILIFGLAMIPHWNLDNISAFPAASVFFRDVLLTIPF
                     CFFSAVFIQVLNPMNIAYRKREPDRVLATRMAIRTHRISYITLIAIILFFSFSFTFSI
                     SHEEAVSAFEQNISALALAAQVIPGQIIHITSTILNIFAVLTAFFGIYLGFHEALKGI
                     VLNVLSRIMDVKNINPLLLTSGICVFIVVTLVIWVSFRVSVLVFFQLGSPLYGIVACI
                     IPFFLIYKVAQLEKLRGLKTWLILLYGILLCLSPLLKLIE"
     gene            complement(30188..31201)
                     /gene="dppF"
                     /locus_tag="OPV72_000625"
     CDS             complement(30188..31201)
                     /gene="dppF"
                     /locus_tag="OPV72_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP binding subunit
                     DppF"
                     /protein_id="HCR9913004.1"
                     /translation="MSTHEATLQQPLLRAIDLKKHYPVKKGIFSPERLVKALDGVSFN
                     LERGKTLAVVGESGCGKSTLGRLLTMVETPTGGELYYQGQDLLKHDPHAQKLRRQKIQ
                     IVFQNPYGSLNPRKKVGQILEEPLLINTSLSKEQRREKALAMMAKVGLKTEHYDRYPH
                     MFSGGQRQRIAIARGLMLDPDVVIADEPVSALDVSVRAQVLNLMMDLQQDMGLSYVFI
                     SHDLSVVEHIADEVMVMYLGRCVEKGTKEQIFNNPRHPYTQALLSATPRLNPDDRRER
                     IKLTGELPSPLNPPPGCAFNARCRRRFGPCTQLQPQLKEYDGQLVACFAVDQDENPQK
                     PLS"
     gene            complement(31198..32181)
                     /gene="dppD"
                     /locus_tag="OPV72_000626"
     CDS             complement(31198..32181)
                     /gene="dppD"
                     /locus_tag="OPV72_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP-binding protein"
                     /protein_id="HCR9913005.1"
                     /translation="MALLNVDQLSVHFGDEGTPFKAVDRISYSVKQGEVVGIVGESGS
                     GKSVSSLAIMGLIDYPGRVMAENLLFNGQDLKRISEKERRNLVGAEVAMIFQDPMTSL
                     NPCYTVGFQIMEAIKVHQGGNKKTRRQRAIDLLNQVGIPDPASRLDVYPHQLSGGMSQ
                     RVMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVA
                     EAAHKIIVMYAGQVVETGAAQDIFRAPRHPYTQALLRALPEFAQDKARLASLPGVVPG
                     KYDRPTGCLLNPRCPHATDRCRAEEPALNQLDDGRQSKCHYPLDDAGRPTL"
     gene            complement(32192..33094)
                     /gene="dppC"
                     /locus_tag="OPV72_000627"
     CDS             complement(32192..33094)
                     /gene="dppC"
                     /locus_tag="OPV72_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010426221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter permease DppC"
                     /protein_id="HCR9913006.1"
                     /translation="MSQVTENNVNAAPAPMTPLREFWHYFKRNKGAVVGLAYVLIVIL
                     IAVFANFIAPYNPAEQFRDALLAPPVWQEGGSWAHILGTDDVGRDALSRLMYGARLSL
                     LVGCLVVVLSLVMGIILGLVAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPS
                     IGNAALALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFVNIFPNCLAP
                     LIVQASLGFSNAILDMAALGFLGMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAI
                     LLTVLAFNLMGDGLRDALDPKLKQ"
     gene            complement(33104..34123)
                     /gene="dppB"
                     /locus_tag="OPV72_000628"
     CDS             complement(33104..34123)
                     /gene="dppB"
                     /locus_tag="OPV72_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter permease DppB"
                     /protein_id="HCR9913007.1"
                     /translation="MLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVMIMAGERGI
                     SPERHAQLLAELGLDKPMWQQYLHYIWGVMHGDLGISLKSRIPVWDEFVPRFKATLEL
                     GVCAMIFAVAVGIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSVHW
                     NLTPVSGRVSDMVFLDDTNPLTGFMLIDTAIWGEEGNFIDALAHMILPAMVLGTIPLA
                     VIVRMTRSSMLEVLGEDYIRTARAKGLTRMRVIIVHALRNAMLPVVTVIGLQVGTLLA
                     GAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMIILVNLLVDLLYGVVNPR
                     IRHKK"
     gene            complement(34280..35887)
                     /locus_tag="OPV72_000629"
     CDS             complement(34280..35887)
                     /locus_tag="OPV72_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCR9913008.1"
                     /translation="MSISLKKSGMLKLGLSLVAMTVAASVQAKTLVYCSEGSPEGFNP
                     QLFTSGTTYDASSVPIYNRLVEFKTGTTEVIPGLAEKWDISEDGKTYTFHLRKGVKWQ
                     SSKDFKPTRELNADDVVFSFDRQKNEQNPYHKVSGGSYEYFEGMGLPDLISEVKKVDD
                     HTVQFVLTRPEAPFLADLAMDFASILSKEYADNMLKAGTPEKVDLNPVGTGPFQLVQY
                     QKDSRILYKAFDGYWGTKPKIDRLVFSITPDASVRYAKLQKNECQVMPYPNPADIARM
                     KEDKNINLMEQAGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKEAIIKAVYQGAGVAA
                     KNLIPPTMWGYNDDIKDYGYDPEKAKALLKEAGLEKGFTIDLWAMPVQRPYNPNARRM
                     AEMIQADWAKIGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSC
                     DAAQQGSNYSKWCYKPFEDLIQPARATDDHNKRIELYKQAQVVMHDQAPALIIAHSTV
                     YEPVRKEVKGYVVDPLGKHHFENVSVE"
     gene            complement(36443..37767)
                     /locus_tag="OPV72_000630"
                     /pseudo
     CDS             complement(36443..37767)
                     /locus_tag="OPV72_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462533.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-xanthine permease"
     gene            complement(37825..38949)
                     /locus_tag="OPV72_000631"
     CDS             complement(37825..38949)
                     /locus_tag="OPV72_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aryl-sulfate sulfotransferase"
                     /protein_id="HCR9913009.1"
                     /translation="MAHLTQDSTFTLGRRPAGLIYADKAKSFGGYTLFAPQTAEGRVY
                     LVDEQGEVAHQWQLPVRAGRDAVLLPNGNLGYNGSHRTSANLYPAWDLWHGGDFYEVT
                     PDNEIVWHYEDIYHHHDAQWLANGNLLYTAASPLPADIAARVTGGDPRRDAPDGVIQS
                     DVVKEVNRDGEVVWEWRAWEHLNPEDFPIHDIFDRRHWPMINGLSVTRDGLVLMSLRT
                     TSGVIAVDKESGKVIWHAGPEVVAQQHTPVEMENGSILVFDNGNLRPGVTSPHSTVLE
                     FDPQIKAITWQYRDIFPPAFFSPYMGSAQRLANGNTFICESAFGRLFEVTPEGETVWE
                     YIIPFFNEYPEHLSKGIIPGKQNSAFRAHRYAADAISWLK"
     gene            39099..40106
                     /locus_tag="OPV72_000632"
     CDS             39099..40106
                     /locus_tag="OPV72_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HCR9913010.1"
                     /translation="MAVQNKKRAKLIDVARHAGVSPGTVSNALHNTRFVEPQTRRRIE
                     EAIVALNYTPNIRARQLRTGKTNTIALLSSVPLAIASGASRLGFMMEVALTSAMMALE
                     KQHALILVPPGVNPLDAVSFDAAILIEPAENDPQLQALAQAGIPCVTIGRTPGTDTPV
                     PWVELHSAATAQLLLTHLEASGASKCALFVGNTRRTSVLESEAAYQRWCAGRQDPVVY
                     SLNESEGENAGYQAAQQLLQAHPDVDGVLVLIDTFASGAVRAFQEQDIAIPEQIRVVT
                     RYDGIRARESLPPLTAVNMHLDEVARQAITLLFAVLSGEKVSYSDGIMPELVVRASTC
                     R"
     gene            complement(40097..40215)
                     /locus_tag="OPV72_000633"
     ncRNA           complement(40097..40215)
                     /ncRNA_class="other"
                     /locus_tag="OPV72_000633"
                     /product="RtT sRNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00391"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="rtT sRNA, processed from tyrT transcript; Derived
                     by automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00391"
     gene            complement(40251..40327)
                     /locus_tag="OPV72_000634"
     tRNA            complement(40251..40327)
                     /locus_tag="OPV72_000634"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(40291..40293),aa:Pro,seq:cgg)
     gene            complement(40418..42049)
                     /gene="eptB"
                     /locus_tag="OPV72_000635"
     CDS             complement(40418..42049)
                     /gene="eptB"
                     /locus_tag="OPV72_000635"
                     /EC_number="2.7.8.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kdo(2)-lipid A phosphoethanolamine
                     7''-transferase"
                     /protein_id="HCR9913011.1"
                     /translation="MRYIKSMTQQKLSFLLALYIGLFMNCAVFYRRFGSYAQEFTIWK
                     GLSAVVELGATVLVTFFLLRLLSLFGRRVWRVLATLVVLFSAGASYYMTFLNVVIGYG
                     IIASVMTTDIDLSKEVVGLHFVLWLIAVSVLPLIFIWSNHCRYTLLRQLRTPGQRFRS
                     AAVVILAGVMVWAPIRLLDVQQKKFERATGIDLPSYGGVVANSYLPSNWLSALGLYAW
                     AQVDESSDNNSLINPARKFTYVAPKDGDDTYVVFIIGETTRWDHMGIFGYERNTTPKL
                     SLRCMFVREGGADNNPQRTLKEQNVFAVLKQLGFSSDLYAMQSEMWFYSNTMADNISY
                     REQIGAEPRNRGKTVDDMLLIDEMQNSLAQNPEGKHLIILHTKGSHFNYTQRYPRSYA
                     QWKPECIGVDSGCTKAQMINSYDNSVTYVDHFITSVFDQLRDKKAIVFYAADHGESIN
                     EREHLHGTPRNMAPPEQFRVPMLVWMSDKYLASPQHAQMSAHLKQQAEIKVPRRHVEL
                     YDTIMGCLGYTSPNGGINQNNNWCHIPDAQKVAAK"
BASE COUNT         9745 a        12032 c        10975 g         9439 t
ORIGIN      
        1 tctgcttttc gccttatgtg ttacaaaaaa taaagtagca cattttgtta aaaaatagcc
       61 aatccgcctg aaaaccgcga cgatgggtca atgacaatac cgtatatgta catgcatttc
      121 tctctcccac tacacccgcg gctatcagcg tgttttaccg ctctcgtccc gtttatcggc
      181 tttttggcgc taaaatgcct agccggaagg cgataaatcc gccgcgcaac gcgatcagac
      241 gtattcgtca cgcgagcaat gattgcgaaa gggcttatta gatgctagaa aatcaataaa
      301 accagccgct tcagcgtcac tgtttcaata aaaacaataa tagagcctga tgatggataa
      361 aatatatgca atgaaattgt ttgtgcgcgt ggcggaacgg gaaagttttt cccgcgcagc
      421 agaagatatc ggccttccca aaggcagcgt ctcacggcaa atacaagcgt tagaacatca
      481 actgggcatc cgcctgctcc accgcaccac ccggcgggta cagcttactc aggacgggat
      541 ggtttactac gaacgggcaa aagatctgtt gagtaacctg gatgaactgg agggtctttt
      601 ccagcctgat cccgccagta tcagcggcaa aatacgggta gatatcccgc caggtctcgc
      661 aaacagcctt atcatgccgc gcctgctcac ttttttgcat cagtatcccg gcattgcgct
      721 ggaactttgt agtagcgatc gacaggtcga tttactacgg gaagatttcg actgtgtggt
      781 gcgcacagag ccgctacatg cgccagggat actgacgcgc ccgcttggca aactaagaag
      841 ggtgaactgc gccagcccac aatacctggc gcgctttgga tatccagaaa accttgacga
      901 cctcgcctca catgcgatgg tgcattattc attgaccccg ggagtctctt caccgggttt
      961 tgccttcgaa actccccacg gtatgcagtg ggtaaaaacc ggcggaatgc taacggtaaa
     1021 cagtacggag acctggcata cggcctgtct ggcaggatta gggatcattc agacgccgcg
     1081 cattgctgta cgggaggcgt tacgcgccgg agcgctcatt gaaattttac cgcaatatcg
     1141 cgccgctcca ctgccggtga cgctgcatta tccccatcgc cgtaatcttt cccgccgggt
     1201 acacctgttt atggtatggc tgactgaaac cattaaagag gccgcagagt agccgcattt
     1261 tcagcatcca ccggggagaa gctatactga tatattctat taatgatgaa ggactaccga
     1321 cctgatgacg caggaaaatg acgtaaaacg ccctattcag gaactggagc acgacccgat
     1381 acaaaaaata gaaacgcagc cgcatgacgc cccggaaaaa aacgaaaagg caaatcaggc
     1441 gttgcattcc gtcaccaccc tgatgcaaaa aatacagcgt caaccgatgg tggcccacct
     1501 cattcgcgcg accgaacgtt ttaacgatcg actgggtaat cagtttggcg cggctatcac
     1561 ctacttttcg tttctgtcga tgatcccgat aatgatggtg tcctttgccg cggcaggttt
     1621 tatcctcgcc tcgcacccta atctactgga agatattttc agcaagatat tgatgaatgt
     1681 gagcgatcct acgctggcgt ccacgcttaa aaatacgatt aatacggcgg ttcaacagcg
     1741 taccacggta gggctggtcg gactgggtat cgcgctctat tccggcgtta actggatggg
     1801 caacctgcgg gaagcgattc gcgcccagtc acgggacgtc tgggagcgca agccgcagga
     1861 tcaggagaaa atctggctca aatatctgcg cgattttatc tcgctgattg gattattaat
     1921 cgctttaatc attacgctgt ccattacttc catcgccggt tccgcccagc agatgatcat
     1981 ctccgccttg tatctcgaca gcatcgaatg gttaaaaccg gcctggcatt tgatcggtct
     2041 ggccatctct atttttgcca actatctgct tttcttctgg attttctggc gactgcctcg
     2101 ccatcgtccc cgtaaaaaag cgttgattcg cgggacattt atcgccgcta tcggttttga
     2161 ggtgattaaa atcattatga cttatacgct gccgtcactg gtgaaatcgc cttccggcgc
     2221 ggcgtttggc tccgtactcg gtctgatggc attcttctac ttttttgccc gcctgacgtt
     2281 attctgcgcg gcctggatag ccaccgccga atataaggac gacccgcgaa tgccgggtaa
     2341 aacgcaacgc tagtctgcgg cttgctgccg aatggcacgc acggcgtcgt cattcggcct
     2401 actgctgtat ggacccaggc caggtatgta aagcgtaccc ggcggtacaa tcaggcacgt
     2461 ccttccgcct catctcattg tttcagcata tcaatccggt aattaacttt tatttaacca
     2521 gaaaccagtt ttatccacca atcctaaaat tatgtgaagc atttcataga cgcaaaatag
     2581 ctggcttaaa cattatcccc tttttgcgct ttttttgacc atttttggct tttgttacac
     2641 attgaaatat aacttttgct gtgcgtaata tggctattcg ttcgctaaaa ataagaaaat
     2701 agtatgcaag caaccgccac aacactcgac catgagcagg aacatgttcc ggtaaactca
     2761 cgcaataaag tcgttattgc ctcgcttatc ggcaccgcga ttgagttctt cgacttctat
     2821 atttacgcca ccgcagcggt gatcgtgttc ccccttatct tcttccccca gggcgatccc
     2881 actgcggcaa cgctacaatc gctcgccacc ttcgctatcg cgtttgtggc gcgtccgatc
     2941 ggctctgcgc tatttggtca cttcggcgac cgggtaggcc gcaaagtcac gctggtggct
     3001 tcgctgctga cgatggggat ctccacggtc attatcggtc tgttaccggg ctacgcgacg
     3061 ataggtattt tcgcgccgct gctgctggcg ctggcgcgtt tcggtcaggg actggggctg
     3121 ggcggcgaat ggggcggcgc agcgttatta gcgacggaga atgcgccgcc gcgcaaacgc
     3181 gcgctgtatg gctccttccc gcagttgggc gcgccgatcg gcttcttttt tgccaatggc
     3241 accttcccgt tgctctcctg gctactgacc gacgagcaat ttatgagctg gggctggcgc
     3301 gtgccgttta tcttctcggc ggtactggtg attatcggcc tgtatgtgcg cgtgtcgctg
     3361 catgaaacgc cggtgtttgc gaaagtcgcc gcagcgaaaa agcaggtaaa aataccgctg
     3421 ggcacgttgc tgacgaagca tgtccacgta accattctcg gcacgtttat catgctggcg
     3481 acctacacgc tgttctatat catgaccgtc tattccatga cttacagcac tgccgccgcg
     3541 ccggtggggc ttggcttgcc gcgcaatgaa atactgtgga tgctgatgat ggcggtgatt
     3601 ggtttcggcg tgatggtgcc cgtcgccggc ctgctggcgg acgcatttgg ccgtcggaaa
     3661 agcatggtca tcattaccac gctcatcatt ctcttcgcgt tgttcgcctt tactccgctg
     3721 ctgggttcag gcaatccagc gctggtattc gtgttcctgt tgttaggtct gagcctgatg
     3781 gggctgacct tcggcccaat gggagcgctg ctgccggagc tatttccgac ggaagtacgc
     3841 tataccggcg catcgttttc ctacaatgtg tcatcgattc tgggcgcttc cgtcgcgccg
     3901 tatattgccg catggctgca aagccactac gggctggcgg cggtaggggt ttacctggcg
     3961 tcaatggcgg cgctgacgct gattgcactg ctgttaaccc atgagacgcg tcatcaggcg
     4021 ttgtaatagg gcgccggatg gcgtcatccg gcgcgacgtt tcacgttact gcttcatctg
     4081 cgttaaaatc gtccggcact gattggcttc gccctcagag ggcgaaatga gcgctaatag
     4141 cgcggcggcg ggcgttacca acgtcgccag cgctgccgca accgcgccgc gcgcaatcag
     4201 cgggccgggc ttgacgcccg cctgcggatt tttaaatgtc ccgcgcacgt aaagcggcga
     4261 tcgcagcgta ataatacgaa tccccttact ttccggatca atggttaaat cgagctgttc
     4321 agaggcgaag ctcgccgtac cggtcacgtt aatcaacgca ttttctgtat caaaagcaaa
     4381 aatttgcggt cgcgccacgc cgttcgcaat attgagattc gccgccgcgc agttaacccg
     4441 cacttcgtca tcgccaaaaa tctgcccgat aatatagttg ccgacgttca gccccacgat
     4501 ttccatcagg ttgcggctaa tcaatccatc attcatcaat aatttgagat tgccgttact
     4561 gttgccaagc agcgcggcga ccgaattgcc cgtgccgcga atatccgcat cgccgttcag
     4621 ctcgcccagc gttttctgca tcagctccac atccggcatc agttctttaa gcttcagccg
     4681 acgcgcctgt atatccgccc gcccctgcat cggcttttta tccccttcca gatggatgtt
     4741 ggagacaata ctgccgcctg ccagaccaaa cttcagcggc tgtagacgta agtcggcgtt
     4801 tttcaggatg atatgggtcg aaagatcgct aatcggtaga ctgccgccat gctcaatacg
     4861 ccggccttta aaccggacat cggcgtccat gacgtcccat ttgtcggttt caaagcgatc
     4921 gtaaggcaac actttatccg ccggctgaac attcttctcg cctttgcgct gttcagaccg
     4981 tttcgactgc tcagcgtctt tcccggaatc cacgccaatc agcggcccaa gatcggccag
     5041 gcgtaactgg cgcgattcga catcgccttc cagtttgggg ctcggtttac cggtggtata
     5101 agtgaaggtg ccgtggatat cactgtcgcc aatgcgcccg ttaaaaccgc gataattaaa
     5161 taccgatgac ttttcggcgt caattttcgc taccaatcgc ccatcggtct caaacggcgg
     5221 cgtatccggc agcagcacgc cggttaaatc atataaatcg cccagtgaat cgccagagaa
     5281 tttaagccgc agatcgacgc cgcccatttt catcggctcg ttcaccacgc cgctaaaagc
     5341 cacccgcgta ttgccagagc ggaaatcggc ctgcacagga aaaggcgtac tttcgctacg
     5401 tagcgccagc ataccgccta ttttgcccgt accggtcaac ggttccccgt tataacgccc
     5461 ctgcgccttc aggccgaaga catagtcgcc cacggtggat ttgtctgctt tgcctttcgt
     5521 tcccgtcact tcgctgaacg gcaacggttt gcctaacgga tcgaccagaa tagtgatatc
     5581 cgctttactg accttatcat cgatcgcgat tcgcccctgg tcgaagagaa tattatccag
     5641 ccggaaggac caggcggaag gtttagcatt ggggtccgta ttcttgtctt gcgcgaggtt
     5701 aaaggtccag ttattggttt tctcggacag acgaataaga cgcgcgtcgg gtttcaccag
     5761 tttgatccac ggcagccaga cggttttggt caggagcgcc agcggggcaa gcgtcgcctc
     5821 aacgcgtggc agatgcacca tcgtgacttc cggaatatcc ggcggattgc cgagaatgac
     5881 gtcttccgcg tgaacatgcg gccacggtac ccagcttcgc cagccggact cctgtttttg
     5941 gcgttcccac accacgccta aatcgccgcg aatagcgaaa ggccggttca attcggtaga
     6001 gactttctgg ttgatggtcg gtttgaggcg gttccagtca aatgttgcga tcaacaaaat
     6061 cactatggcg atcaacaaca agaaagtccc tgtgatggcg gcggttattt tgcctgcttt
     6121 agtcatgtgt tatttcctca cttcttccct tgcctgtcct aaagatagtt cagccagacg
     6181 aaaaaggagg atgaccgcac ctcgtaatac cacgtattac gggaacagtc tggcgttaca
     6241 gggtcagaat cacctcttcg agcgatatca gcggcacggg tcgagaaaga aaatagccct
     6301 gggcggcaaa ggcgggcgaa cgctgcacat cacgccactc ttccagagtc tccacgcctt
     6361 cgacaataac gccgcggcag tagcggttca tcagttgcag cagcagaatg aacaggttgc
     6421 gcccctccgg ggactggcgc agcatgacga acagctcgcg cgccacttta atgtagtcat
     6481 aacgcacttc gctcagcgct gaaaaattgg ccataccagt accaaaatca tccagccaca
     6541 gcgggacgaa ctcacacatc gaggcgaaag aggagtcttt cggcaaacga atatgttcca
     6601 ccagttcaaa acgcagccag ggtaagcgct ccatcgctgc cagaatgtcc ggctgttgtc
     6661 gcatggcaat cagcgtaggg ccgtcgacat tgactgatgc caataagcga tggcgagtga
     6721 aaaaatccgc tttttgttca agctgatgaa gttgttcttt tactacgtca atgcggtgtc
     6781 gaaccgctaa ttccgcgaaa taacgatccg gggcaatacg tctggaaggg ttatcaggat
     6841 gggtgacggc agtgagaagt tcaaccgtca tcagacggcc atccgtctgg tatatcggct
     6901 ggtaagtata ggcacgctcg cattgcagcc aatagcgccg ttcctgcaaa ttctctatac
     6961 ctgcatcagg aacgcgtagc tgctggataa cctgctttat catctcagtt gtcctgttaa
     7021 tgggagtgtg acagtccgga ctcgtcaaag gttatcggcg ttcaggcaga gaactttacc
     7081 ctcggtccct ggcaaaataa aaacagacca cgaaacttgt caaaaatacg cacttgctca
     7141 aaaaaataat ggaccgatgt tttaatatta ttgaccgcta aacatccaca gcgcacacta
     7201 acgctaattt ttacagatca ggttcacgac tatgtctaaa aagattgccg tgattggcga
     7261 atgcatgatt gagctgtcgc agaaaggcgc tgatgttcag cgcggcttcg gcggcgacac
     7321 gctgaatacc tccgtttata ttgcccgtca ggtcgattct gccgctctgg ccgttcacta
     7381 tgtaacggcg ctgggtaccg acagtttcag ccaacagatg ctggaggcgt ggcagcatga
     7441 aaatgtggat acctcgctaa cgcagcggat ggaaaatcgc ctgccaggcc tctattacat
     7501 cgaaaccgat gacactggcg agcgtacctt ctactactgg cgtaacgaag cggcagcgaa
     7561 attctggctg gagagcgagc agtcagcggc tatctgcgag acgctggcga ccttcgatta
     7621 tctctacctg agcggcatta gcctcgcgat tttaagcccg accagccgtg ataagctgct
     7681 gtctttattg cgtgaatgcc gggccaacgg cgggaaagtc atttttgata ataactatcg
     7741 cccgcgttta tggacaagtc gcgaagaaac gcagcaggtc tatcaaaaga tgctggaatg
     7801 tactgatatc gccttcctga cactggacga tgaagacgcg ctatggggta agcaaccggt
     7861 ggaagaggtc attgctcgca cccatgcggc aggcgtacag gaagtggtgg taaaacgcgg
     7921 ggcggactct tgcctggtct cgattcaggg cgaggcgctc attgacgttc cggcagtaaa
     7981 actgccgaaa gagaaagtga tagacaccac tgccgcaggc gactccttca gcgccggtta
     8041 tctggccgtt cgtttgacgg gcggcagcgc gacggatgcc gcgaagcgcg gacacctgac
     8101 ggccagcacg gtgattcagt accgtggggc cattattccg cacgacgcga tgccgcagta
     8161 agtcattcgt tcttgcccgg tggcgctgcg cttaccgggc cgacaggcgg ccgcttactg
     8221 tgccgccggt gtttccgtca cttccggatg cgcctcatct gcttcaacag cggcggcagt
     8281 tgccggaacc atgatttcat cccacgtcgc ctttaacgcc ttcatattaa attccggctc
     8341 gccttgcggt tgcagcaaaa ttaatgccat ctcctgcgat agctgctgac gtagattctg
     8401 attgagcata tcgacggtca ggctgttgag gaaattctga cgcagcttct gatactgctc
     8461 cggcgcgata tccaccacct gattctgcag cgagcgcata cgctgtccag tcaaaatgtc
     8521 agtatcggta cgcgcgtagg tcgcgaatag cttttgcaat tcgagatttt tctgcgccac
     8581 cagcgcagta aactcctctt ccgacaaacc tttatcgcgt actttcgcca gttcattcgc
     8641 caccaggctc aaattggtat tgagcttatc attaggtgat tcaatgttga tggcgcactg
     8701 cgcgcgcagg aacagaaccc ggcagtcaaa ccccagacca atatctttcg cgttattttt
     8761 agtaagctct tgctggatat gccagaacag cgcttcgcgc gccagatccg cctgccagta
     8821 gcgcaacagc gccgccgact cgcgaatcgg ttgccacggc gtatcccaca taatggagag
     8881 acgatcctgg cgcaccgcat cggtcataat gctcactgat tccgcccgca gcggcgaaag
     8941 cgtcggcacc ggggcgggcg tttcgcgttt acctttcagc gtaccgaacg ttttattgat
     9001 ctgctcggcg acggagcgcg catcaatgtt gccgacaaca atcagcgtca tggcatccgg
     9061 ggtgtaccat ttttcataga aagcctgaat tttggctgcg tctaccggct gctttaacgg
     9121 ttccgcggga tcgtgcccca ataacgccga tcctttcagc cgataacgcc accagccctc
     9181 tttagtatct gctggccacg tcgcaaccat atcttcgctg cttaacgcat gattcaccgt
     9241 ctctggcgta atggttaatt taccggagac gttagccaga taggtcagcg cttctttcag
     9301 cagatcgtta cggttattgg gtaaactgag gctatagagc gtggaatcat aagaaacaat
     9361 aacgggcggc atgggacgtt tcggatcaaa tccttgctgc cataaagaac gtgcctgtgc
     9421 ggcatccaga ccaccgcttt gcgtcagcgc gatacgggga atcgcatggc taaacccgct
     9481 ctgttgcgta ctttcggtga gcgaaccggt attaacctgt agacgaactt caatacgatc
     9541 gctggggcgc tgaggcgtag ccaacacttg ccactgtaac ccattagcca gcgtcccctg
     9601 ttgccatgcc ggatcgggct ggagcgcatc tgcctgcaca tagccggcag aggccaacat
     9661 caacagactg cccgctaaga gtcgaatttt tgtgccctgc atgtgaaccc ctgatcaaca
     9721 atcctggtaa taaaaagaca gccccggcag ggatgcctga atatgacgta aaaacacttc
     9781 gtgttagacc gcgagaacct aaaaatgtca cggaagaagt gaaataatcc ctaagcatca
     9841 tgctgtatgc tttgggcgca ggggtcaatt atgcgcaaac acccgcagtc ctggaaggga
     9901 ctacgggcat aagtggcgag attaggagga aatttcgtgc gttttgccat ccggcgcacg
     9961 attattaagc acatcgtcca gcttttggtg atctaactct ttcacccatt tggcaaccac
    10021 caccgtcgcc acgccgttac ccaccaggtt agtcagcgcg cgcgcttcgg acataaagcg
    10081 gtcgataccg aggattaacg ccagtcccgc caccggcaaa tgacctacgg cggagatagt
    10141 ggccgccagc acgataaagc cgcttccggt cacgcccgcg gcgccttttg acgatagcag
    10201 cagcacgacc agcaacgtga tctggtggaa gatatccata tggctgttgg tcgcctgggc
    10261 gataaacacc gccgccatcg tcaggtagat agaggtgcca tcaaggttga acgaataccc
    10321 cgtcgggatc accagcccca ccaccgattt acggcacccc agtttttcca tcttatcgag
    10381 catacgcggc aacgctgact cggaagagga ggtgccgagc acaatgagta attcttcccg
    10441 gatatagcga ataaatttaa aaatgctaaa gcccgttacc cgtgcaatcg tccccagcac
    10501 caccaccacg aagagaatac aggtgatata gaagcagata atgagctgcc ccagttgcac
    10561 cagagaaccg acgccgtatt taccgatggt gaaggccatc gcgccgaatg cgccaatcgg
    10621 cgccaggcgc atgatcatat tgatgatgcc gaaaatgacc tgcgaaaaac tctcaatcac
    10681 attgaaaatg agctggcctt tgctgcccaa acggtgcagc gcaaaaccaa acaacaccgc
    10741 aaacagtaag acctgcagaa tgttgccgct ggcaaacgcg ccgatcacgc tgcccggtat
    10801 gacatccatc aggaaggcaa taatgccctg ctccttggct tgtgcggcat aaacggccac
    10861 cgcctgcgca tccagcgttg ccggatcgac gttcatcccg gcgccaggtt gcacaacgtt
    10921 gacgatgata agaccgttaa tcagcgcaat cgtactgaca atttcaaagt aaagcagcgc
    10981 gaccgcgccg gtacgcccca ccgctttcat gctttccatg cctgcgatgc ccgtcacgac
    11041 agtacagaaa atgacaggag cgatgatcat cttaatgagc ttaacgaacg cgtcgccaag
    11101 cggtttcatt tgtgcgccca gttcaggata gtaatggcca aggagaatac caatggcgat
    11161 tgctgtcagg acctgaaaat aaagactttt gaacagagag gttttcatag ggtgtccttg
    11221 aagtaaaaac cacaggtctt gtaaggttat gagtaacctg cggccttaaa ataacaccca
    11281 cacaacatga cagaaatgcg ccaggatcat aattgaaaca aaaatgttaa aaagtttgag
    11341 ctgactcgca caagcgcgac cttttttaac ttttgtaatc aggattttcg tgcgacagat
    11401 accgttcttc aaagatatcc gcgggaacgg gccgagcaaa caggaagcct tgcgcgacgt
    11461 tgactcccgc ctgttccagc cacgcgcgtt gcgcctcgtc ctccacgccc tcggcaatca
    11521 attgtaaatt aagactgcgg gccatcagga taatcgccgt caccatactg tgatcatccg
    11581 gtaacccatc gacaaacatt ttatcaattt taaggatatc gaccggtagc gacttcatat
    11641 gctgtaactg gcgcagcccc gcgtaaccca tgccaaaatc atccagtgcg atacgcacgc
    11701 cagcattacg taacggacgt aagatagcga cggcagcgtg cggatcgtcg atacggcggc
    11761 tttcagtgac ctcaagaatc agcgtacccg gttgaatacg atagcggttt aacaattcca
    11821 gcagatccga caccatgcca gggtgcatga gctgtaacgc ggaaagattg acggagagcg
    11881 gcaatgtcac gccgcgctcc tgccaggcgg caagctggcg gcaggactct tccagcaccc
    11941 aatggcccac cgtgaccatc aggccgcagg attcaatgcg ctcaatcagc ccctccggca
    12001 attcccagct accgtccggc tgctgcatac gtaacaaggc ttcggcgctt aatacgttgc
    12061 cgctgcgcat ctcgacctgc ggctgcagcc aaatggcaaa ctgatggtta tccagcgcgg
    12121 taaggatatc gctctcttcg gtaaggcgct gttgagcggc ctccatctgc gccgggtcaa
    12181 agaactggat ctgattttta ccttttcggc gcgcggtaaa cgcggcggag acggcgcgac
    12241 catagagcgc ttcggcggtc agatcgccat aatacatcgc aatgccaata ctgcagcttg
    12301 ggcgcagttg aataccctgg atgggcagtc gttcattaat gatagtgagt atttgctgac
    12361 ctaatgtgat ggcgtgccac ggctctttga cgccgtgggc gataatggca aagtcatacc
    12421 cgctgacctg cgtaagcacc atgcgcggcg ccagcaccga cttcagcttc tcaaccagcg
    12481 tcagtaatag aatctcccgc tgcgtttctt gcagcacgcc tgccgtgtca cgcaacgttt
    12541 cgcacgtcac gatgataagc gcggtggtct gttggcgggt gataacctgt tccagcagcg
    12601 ccattaaaaa ggctttattg ggcaactcgg aaaccggaaa acgcatcgcg ttgtccgttt
    12661 gctcctcgcg ttgacgctgc ataagctgct ggttgaggtt atagctgcgc accagcatcc
    12721 caatttcatc atcctgatgc agacgcggca acgccagctg atgtccgatc agctcctgct
    12781 gcggaatgtc gttcagctcg cgggcgattt tgcgcagcgg atgcacaatc aggcggttta
    12841 cgcaccaggc gatggccacc gtcaggatca gcgataaaag taagtaaatg gtcactaacg
    12901 tagagagcgc gctcatgacg aacttgtaca tacggtacga atccgcctgc aatacaaggt
    12961 aggccagcgg ttgcggattg gcgggacgct ccagcgaata aaccggcaaa gaaatttgta
    13021 ccggcagttc gaagagacgc gtcaccataa ccgggacggg gcgttcagga atgaagcgct
    13081 tacgcaacgc ctggaactga ttcggcaata ccacatcggc gcgactcacc acgcccgcag
    13141 gtttaatact ttccagaatg gtttccgcgc cggggagatc cgcttttaaa atcgcggaag
    13201 aaagaggttc ccgaacagag cgcgcgatgc tttccagttg cgtagccgtg ttgtagcggt
    13261 tctgctgtac cagatggaac aacaaaacgg tgcaaaagac aaaaacaaac accatgacaa
    13321 cggccgcaac cattgccatc tgtttaattg ttaacgagcg gctgacgcgc aaattgactc
    13381 tccctggata tcccggactg ccgcctgagt atacccgatt gcagcggcat taagagaggc
    13441 tgtatctgaa aaggactttt ctgaataacg gttaatgata gcgtctgatg gcgctgcgct
    13501 tctcaggcct acgacgcctg tcaatacgta ggcctgacgc aatgattacc agtcagcgta
    13561 aggcaccaga ggctgcggcg gtaaatccat atccccctgc cagcctgccg cggaataacg
    13621 gacatacagc agcagatgac tgggggtata atctttcgcc tgctaaatat cgacagccgt
    13681 acccacaaac cagttggcag tgacccggcg ttcaatgagc gcccgcgcgg tatagccaaa
    13741 tccctgactg ctgccgccgc cgttggtctg gtcacgcgca tcctcctgat aatccgccgg
    13801 aatcaaattc atcagcggat aacgcggcat ggtacggttg ccgggagtgc gaccaggata
    13861 ccgagccgcc taactcccac gaccagtttt ccgtacgctg ccgccacatc accggcaccg
    13921 caaacgacag gtattcctgc gggctataat aaccgccctg acccagtgaa taaccgctca
    13981 gatctttgtc gtaatgccag atcatgttat tcagcccgac ggtaacgcgg cggttattct
    14041 cgttaatcac cttatagtaa taaccggtca tccagcgcac gcgccagtta tcttccacat
    14101 ttttaccgct caactggtcg ccgctgagcg acgcccagac accgtttgct tcgcctttat
    14161 catagctgag actgacgccg ccgccgttgg cccgcacgcc gccccatttg gtgccggtat
    14221 tgctgctggc gtccttttgc ccgccaaacg ccagcagcga gctggagatc gggcgacgat
    14281 gcgcgttcag ggtataaccc aacggcccga tatcgtcgct atagctgacg ccgccgacca
    14341 catcaacgac attaaagccc atcggcgtcg tgccgatatc ccagcgccag gtctcattct
    14401 gccagccgac cgccacgctc gcgcccgtat cggcctggct acgatgtccg ctgcatttct
    14461 ccagcgtaca ggtaccccag ttattatcgt atttcccatc tgcatccgta gagaagcgac
    14521 caacatccat attcaccata tcagtacgaa agaacgcccg tccgtccgac cagggcgcat
    14581 ccacctgaag catcgtggta tgcgccttca gatcggagta gccgccagtc ccgctcgacc
    14641 cccaataatc gtgcgccaac gtgacattga gatcctgctg acggtacaac tccgccgcat
    14701 cgctacgcac gccgcgtttt agccagtcat ctttttcatc attgcgcgtc aggcgggtaa
    14761 aggtatcgtt atcctggggg cgaaccggcg taatcgccgc ggcgaccatt gcctctttgt
    14821 aggtctccag cgcccgctgc ggctcgcccg tttgcgcctg aaaagcggcg gcgtcacgca
    14881 ataccatcgc gctttccatt gatggcggct gtgcttttgc ctgcggcgta atgcggttaa
    14941 agatccgcgc cgccgccgtg atatcgccaa gctggagctg cgccagcgcg acgcggcgct
    15001 gcatgttaat agaggtgatt tgcgacgcag gcagcgccgc cagttgagcg cgcgccgcag
    15061 cgttatcgcc ctgtgcgatg tcgatttcca cccgccccag catggcatcg acattacccg
    15121 gttcccgcgc cagaacggcg tcataagcgg cgcgggccgc cgcattatcg ccacgctgct
    15181 gcgcccagtc cgccaacgtt aacgcaatgc gcgtagaggg cggctgctga cgtaacaacg
    15241 cttccgcttc gcgttctttg ccgctatcgc gcaagcggtt agcgctttcc agcacctggt
    15301 tactttacaa tcggcccgcc agttcctgaa tattgctgtt ccactggctg gtcggcaggg
    15361 tattgagatg cgccagcgcc gcccggcccc gatcgctgcc ggaaagataa agcccataag
    15421 catagacctg ttccggatcg tttggcttct gctgcgccag agagcgcatt tgcgcatcgg
    15481 cctgggcgtg ctgtccggcc tgccacagat cgcgtgacag tcgatacgtt acccacacgc
    15541 tccccggatc taatgccagc cggcggcggt gcagttctgc ggcctgcgcc catttgccct
    15601 cgctttccag cgtttccgcc tgctgcgcca gacggtcatt ttccagactg cgttcgatat
    15661 cgtcgatact gcgccgctgg ctggcggaaa gagaagcgat aaacgcggcg gctttttgcg
    15721 gcgactgcta acgataaaga ttcgccagcc cgcgtacagc attggtatta ccgctgtcca
    15781 tacgcagcgt ctgctgataa taacgttcgg cggcggcatt atctttgcgc gccatcgcca
    15841 catcccccag ccccagcacc gcgtagctgt cggtgttatc cactgctcgc gcctgctgat
    15901 agaaacgctc cgcctgagcc agattattcg cttttaaggc cgcgtcgccc tgctgaatta
    15961 acagccagta gcgattgacc ttcagcaggc tctcccactt atcgcggctg ctgctgtgcg
    16021 gcgccatcgc cagcgccttt tcaaactgcg cgacggcgcg ggcgcgatcg ccacgctgtg
    16081 agtatgcctg ccccagcgcg ccgaccgcct cgctgtcgtc ctgccgggcg ctcaccgcct
    16141 gctgcgattg cgcaatagcg ttgccgcctt ctccggcatt aaccgccgcg atgccctgcg
    16201 agcgcgcgcg aaacgccgga tcggctaact gtttttgctg ctcgctaagc tgggcgcggg
    16261 cggcagacac gctatcgcct tcgctaaact gcgtcagata gtcttgcaac gcttttacgc
    16321 tggcgtcgct aaccgggaga tcttttatct gctggtacca gatggcggag gccgcgctgc
    16381 gtcccgtact ggatttcgcc atctgtttta gcaccgcgaa tccctcatcg cgccgcccgc
    16441 tggcgaacaa cagttgcgcc agcgcatttt gcagagcgtt attacccgga ctgacggcat
    16501 tgattttctg tagctggtta atcgcttcgt gacggcgggc gggcaatttc gccacggtcg
    16561 tccagtattc gaccgccagt tcgccctccg gcggataacc tttaaacagc ttgtcgtagc
    16621 tggcgatcgc ttgttcagta tgaccggtcg tcgccagtaa acgcgcctcc tgcaaagact
    16681 ggcgtccttg cggcgtggag agcagcatcg cggtgcggga agattgatac gccgtcgact
    16741 ccggcgccag ttgcgccagc cgatcaagta gcttctgcgc cccgtcgcta tccccctggc
    16801 gcaacagata gcggaaacgg gcggcgataa cctgtggatc attggggtcg atcagctcca
    16861 ggcgatagag cgactgacgg actaagtcct cacggtgcgt ggcctcgccc agccgcacct
    16921 gctccagcaa ctgttgctgc gcggaggtcg ctgcgccggc aagcggtgtt agcgccatac
    16981 caagcgataa ccccaacaat gcccgagaaa cgcccctttt gccaggtaag gcatttcgac
    17041 cgccagccag caaaaaagcg tgcatgagac ttaacgtgaa cttacgcatt cctggcccca
    17101 gtcaggtaat aattcacctt tgacggtgaa gcgaaaacgg tgctgatccc agccttgtcc
    17161 aaagagagtc agcacatagt tgtaataggc atcgctgcca ggaaaatggt ctgcgacccg
    17221 ctgtcgctgc acggcctggg cgccgcgatt ttgcaggaaa ggcagtaaag cggcggaaaa
    17281 cccgaccggc cccgtccctt gcgcattccc gctgacgaca tccactttct ccggtggaac
    17341 gccgtttttc atcgttaacg tcgccatcgg tttaaatcgc gccagtaaac gcgctttttg
    17401 cggatcgcca tcatgcatca ttcccgtcca taaatagacg cgaatcgcat cgtagctact
    17461 gatcagcgtc ttttccgctt tcaactgcca gccttgcttt cataacgcac ccagtccggc
    17521 gagaaacctt tcggcgaggt ttccaacaaa agccgcaaat tggtttcccg tagcgtcgac
    17581 cacggcgcgc caaaacggct aaagtattgc gccaactgcg gcggcagata gcttgggtta
    17641 aaacgccagc tattcgcctc ggcaaagccg attttgccag gtagcagcat tgagcccagc
    17701 cccggcacat tcacgacctc ttcgcgggcg atgcgtttta gcaacgccgt gcccacctcg
    17761 gtataacgcg tctctttcca caggcgaccg gcctccagca gcgaccatgc catccagata
    17821 tcgccgtcgg acgcggagtt gctgtccagc accgaccagg tgtcgggatc tttttgtccc
    17881 cacagccagg cgggcagatg ttcacgcagc gatccctgcg ccagattgtt ttgcgtccag
    17941 ttaaacagtt gcgcgaacgc cggtcgatcg ttcgccgcca gggcaaagaa catggcgtag
    18001 ctctgccctt cggaggtggt aatttttcgc gcatcgcccg gatcgataac gcgtccctgc
    18061 tggctaatgt aatctttctt gaactgttcc cacgcaggcc agctacacgc tgcctgcgca
    18121 tttattgccg tcagcatgac gatcatcgtt atccatccgc gcagcatagt catcatgcgt
    18181 tactcatggt cagggtcgag acgacggcga ctgagaatac gtagcagacg ccacaatacc
    18241 cacgccagta ataccacact gagggccgcc agtaccgcca gcagcaccgg gtgattcgcc
    18301 agcgcatacc acagccgctc aaaccacggc agatgtccga cgtaatagat atcgccaacg
    18361 cgcagactgt gaacgccgga ctcgcggatc accgccacgg aaccaaacat cgcggcgcgt
    18421 ttaccgctgt cgttcacggc gtcgttcagt agctggtaac cgcgcgggct gtcagccagc
    18481 agagcaatca cgctgcgctg atcattaaac ggcgactgga agcccaccac cgccgccatc
    18541 gggccgctgg cggtgacggt ggactgcgca tccgccgcgc gatcggcctc atccggcata
    18601 atcgacggga aagcggtctg ccgcatcggg gtttttaccc agctttgtgt cgcctgcacc
    18661 aacagatcga tacgcttatc gtcttttagc ttgcccggaa tagcgccaat aatcagcaga
    18721 tcggcgtctt tgtcggctat ctgagcgcta tcatcggtga ttgtcagatt aattgccggg
    18781 aaaccggtct gcccgccaat ggcgccgacc gtattcagca gcgtttccat ttgcgcttcg
    18841 gttggggtct tcggcatcac cgccagcgtg tcagacaggt cggccatccg gctgaacggg
    18901 aaacccgcat tggcgaacgc gcgtaaatcc ggcatcgcga taaagtggta atatttcgaa
    18961 aaatcgatag tggagtcatc ccctatcacc acatgattcg gtactggctg gaaagtaata
    19021 cagttgtcca ccgacccgcc cggcatcgga ttcatgtagc ggaaatcaaa acgtagttgg
    19081 ttcatcgccc ccagtttgag cgccggaata gacacatccg ttttaccatc cagcagtccc
    19141 tgaagtaccg gcaggcgcaa caggagtcga ttagtttcct gcgtgctgtt aaggctaaag
    19201 gcttgcaaga actggttatt cagactgata tccagccgcg aactgtcttt ggtcggcggc
    19261 gaggtataac gatagttgag atccatatca ataccgttgc tacgcagcaa atagaggtcc
    19321 ggcggcagat tcaaagaaac gttgatgggc gccggctcca gcccactcga ctggagctgc
    19381 tcttcatagg ttttcagctc gccaaaagtg accgggcgat cggtacgcac ccagttcggc
    19441 gcatcatacg gtttgcgcgc cagcagcggt tttacatcgt tgaccaccac gctggaacca
    19501 cggaagagaa tattcccttg cgcgatacct tttgccgcct gcaacaggtc tttatcatct
    19561 cgaccaaaca cgaccagcaa cttcacatac ggattatccg gatggttcat catctcgata
    19621 accggcgcgt taaccgcagg atgatcgcgc aggaaatcgg ggcgtcgatc gttggtggcg
    19681 aacacgatcg cattgcgatc cggcaggtga ttatacaaca ccgggaagcg ctgaccgcgc
    19741 cagcccgccc gcgagccaaa ccaggacgcg acaatagaag ccgcctgctg ctgcgccaga
    19801 tccggcatgt cagcaaacac tatcggcaac gtcaccggac ggttatcccg cggatcgaaa
    19861 aacggcaccg ggaagtggga cagatcgtta ttcaccgcca gcatgttata ggtcagatcc
    19921 agggcgctat ttcgcccgat gtctaaccac agagtactgc tggccgggtt ttcacacacg
    19981 tcgcgatagt ggccgacaaa ctccagccgc acccggttaa agtcggtgat aaatagcgga
    20041 ttgataggta cctgcgccag cgtctttttc cccaactgct cttttgtcac cggcagtacg
    20101 cccatcagtt catcattgag ataaaccttg agctgcgact gaaccggcag gagcgacggc
    20161 gagggcgtat attccagatt caacaccgct ttcgacgcca cttcatcgct gcgcatacca
    20221 aattcaatgc cgccgttagg gttaacgcca cgcagcgcca tactgcccgg cggcggcgcg
    20281 atttgcgcaa aggtcagctt gacctcgcgc gaaggcgcgg tctgcgccac gacgggcgcc
    20341 tcagttacgg gcgactgcgc aggctcggtg ggttcagcat tgatcaatgg cggcatcgca
    20401 ggcgccgccg ccgtcatgaa agcaggaaac gcgcttaatc ctattaccgc cgcacacatc
    20461 caggacaatt ttcttttcat cgcattatca tcattgttga gcctgagcca taacccgatc
    20521 cgacggctgt atcgccgctt gccgctccgg gcgacgcgga ataaacgata caatccaggc
    20581 aattaacgcc gtcaacgatc ggaaaattac ttttactgaa ggcggcgcga actccgcgag
    20641 gtggcgatat ccgcggaagc ccagcttcag aatatccagc aagctttcca gcggtttatc
    20701 ttccgggaag ctatcttgcc aaagcgccca cgtatcggcg cgagcgaagg tacactgcac
    20761 aaaatcaata tgttgtttgg tggtgagcgg catcagttgc agcccgacct cattgcccgt
    20821 tacgcgcact acctgcgttg gaaagacata ttcctgctgc ccgcgtttaa gcaacagatt
    20881 cactttctgc ccttccagca cctgcgcctg accgttgatc ttgatgccta acccgccgtc
    20941 ggagaagtca tgtacggtac aggagaacaa atgtccatct tcgcgggcga tggcccccgg
    21001 catggcaatc tcgacccgat gcgcgcgcct gacctgttta ctctctaccg aaaccgcaac
    21061 cgcgccgccg agaatgacca ggttatagaa gacccacacc aggctaacga tgacggtcag
    21121 cgtttcattt tccggcccat aatagtatcg ccatacgccc gccgccacgc cgagcaggtt
    21181 aagcaagaca aggaagatat acggacgcga gattacccag tcgacgtact tctcttccac
    21241 cagtccgcct ttcgccgtga cgttaaattt ccctttgtgc ggattgatca acgcgaccag
    21301 agtcggtggt gcgatatacc atgccagtac cgtttcatag atttcactcc agaaagagtg
    21361 acgatacttg ccctgaatct tcgagttagt caggctggcg tggaccatgt gcggtatcac
    21421 aaatagcgca atcatcaacg caggcgcata aatgatatag gcgtgcagca gcagaaaagc
    21481 cagcggcgcg gtcagaaaga tcaggcgcgg aatgccggac aagaaatgga acatcgcgtt
    21541 gaggtagcac agccgctgcg ccagttttaa gcctttacca aacagagggt tatcgaggcg
    21601 gaaaatttgc accatgcccc gcgcccaacg aatacgctgc ccgatatgcg ccgacaggct
    21661 ttccgtcgcc agccccgccg actgcggaat gcgcatatac gctgaggtat aacctcgccg
    21721 gtgcagccgg agcgaagtat gcgcatcttc cgtcaccgtc tcaacggcga taccgccaat
    21781 ctcatccagc ggcttacggc gaatcaccgc gcacgatccg caaaagaaag tggcatccca
    21841 catatcgtta ccgtcctgca ccagtccgta aaacagcgtg ccttcgttag gcgttttacg
    21901 aaaacgtccc aggttgcgct caaacgggtc cggggagaag aaatgatgcg gcgtctgcat
    21961 catcgccagc tgtttctctt tcaggaacca gcccattgtc atttgcagaa acgagcgcgt
    22021 cggtacatgg tcgcaatcga agatcgccac aaactcgcct ttcgcgtgtt ttaacgcatt
    22081 gttgatgttg ccggctttgg cgtgttcatg cgtagcgcgg gcaatgtaat gcacgccaac
    22141 atgccgggca aactgacgaa atgattcgcg cccgccgtca tcaaggatcc agatattcag
    22201 cttgtccttc ggccagtcaa tgccaagcga agcgtaaatg gtatttttga ccacattaag
    22261 gtcttcgtta taggtcggta caaaaatatc caccgtcggc cactgcgaca tctctttcgg
    22321 caacggcacc ggttgacgat ttaacggcca caccacctgg aagtacccca gcaccagcac
    22381 aatccaggcg taggtttccg caaacagcag aatcagtccg cacaccagac tgaccgggtc
    22441 gtcccaattt agcgtcgagg tatagcgcca ccagatataa cgacaggaga ccgttagcga
    22501 cagcacgatg agcatcagcg cggaaaagcg tcccggcata cgtcgtacca acagcgcaac
    22561 gccccacagc aacagcagaa agataaattg cgatagcggg ttaaatggct gcgtaataca
    22621 gatcagcgcc agtatcagtg aaaaggtcac gataacgccc agaataaaac gccgggcgcc
    22681 gttgctaaga tgtcccagct ctttttcctt ttccaggtgc gttgtctttt ggcgcacccg
    22741 ttccggtaag gtatccatcc attgatggta acgtccacga acgtccttca ggcgcgcaaa
    22801 tgaccgccag cgcggttcat gacgttcttt agtcgacgag atcatcacca gccagagggt
    22861 ctgaatgagg taacgggccg ggtccagcgg gcgcgggcgg gcggcgttaa tatgcggata
    22921 aagcgcttta tgcccgtcgc gaatacgctg ccagcgcgga tgctcaagcg gaaacactat
    22981 ccacgccaga atcgtccaca ggcagccgag cgctgcgcta aacggcgacg cgccgtggcg
    23041 gcggtaaccc tgatagcgct cgctcaagcg cgcgctaacc ggcgggataa gcagccaccg
    23101 ggaaagggcg ctcatcgcag gctcccggca gacgttttgt cgcccgcatc gtgcagcagg
    23161 caccagttcg ccagcgttaa cacctcttcg gcggctaacg aatcgctgcg atactcgcct
    23221 aacggctgtt tcgacgccat gcactccgcc atcgcttcat cgcgatggat cacaataggc
    23281 agcaaccggc gctggctttg cagccagacc tggtacagat cgtcctgtaa ctgactgcca
    23341 atgcgtaagt cattgatcag aatatgcgct ccggcaggca acgcctgctg atgaaggcga
    23401 atatggcagt tagcgtcaac ctgggctatc gccagcgtat ggtcgcagag gctcaccagc
    23461 tgtcgtgtca gcggtgactc gccgtagggc aagtccagta aaatccagct ataacgcccg
    23521 ctcgctttca gcgcctggat agccgatccg atctctccca gcgtctcctg ccaggcctgc
    23581 ggattttccc attcttgcga ggtgagctgt ccaaacggca gtagatcaag ctgcgaggta
    23641 taacgtaacc cggcatcgcg ccagtcctgg ccgtccagca acgatcgcgc ccaaccgccc
    23701 tgatggacga agtcgacgtt aaacgacatg cgcagcaggt tatcggggct ggcgtcaatc
    23761 accaggacat tttcccctaa gatttgtaac gcccaggcga gtgctgcggt gagagatgtg
    23821 gttcccaccc cgccgcgcac gccctgcagt cccagaatcg ccattcatgg cttccttaat
    23881 gaatgtggtt gcgcaaattc agccaggagc ggccatcttt taatcgccgc cgccaactgt
    23941 tcgcgttggg aaatatcggt ataatctatt tcgggtagtg aaaacgcctg gcttaatgcc
    24001 agaaaatcat tttgaaaagt gtagcccaac gttggatcgg actgagcgcc aggttcattg
    24061 ttatacattc tggttgctcc tttttaaata tttctcactg gcagcattac gccccgtcgt
    24121 caatacggga gaacgcgcat ttttcatctt tccgtgacat catttataat gtgtaaaaat
    24181 gcaaagcgca gagttacagg gcatcctgcc ggacaaattg attcacatgc taaatctgat
    24241 gcgttttaat ttcaatgtta ggtttatttc tgtgctttcg ctagtaaact gataaacagt
    24301 taaaatagtg acatgaggga cactgtggac cccgtatttt ctctcggcat ctcatcatta
    24361 tgggatgaac tgcgccatat gccaaccggc ggcgtctggt gggttaacgc cgatcgccag
    24421 caagatgcca tcagcctggt gaatcaaacg attgcgtcac aaacggagaa tgcaaatgtc
    24481 gccgtcatcg gcatggaagg cgatcctggc aaagtaatca aattagatga atctcacggt
    24541 ccggagaaaa tccgcttatt taccatgccg gattcagaaa aagggctata ctctttgccc
    24601 cacgatttgc tttgttctgt taacccgacg cattactttt tcattcttat ttgtgcaaat
    24661 aacacgtggc ggaatataac gtcagaaagc ctgcataaat ggctggaaaa aatgaataaa
    24721 tggactcgtt ttcatcactg ttcattgttg gttattaccc cttgtaataa tagtgataaa
    24781 cagtcctcgt tgttgatggg cgagtatcgc tcacttttcg gcctcgccag tttacgtttt
    24841 cagggcgacc aacatttgtt cgatattgcc ttctggtgta acgaaaaagg cgtcagcgcc
    24901 cgacagcagt tattgctatg tcagcaggac gaacgctgga cgctatccca tcaggaggag
    24961 acggcaattc agccgcgtag cgacgaaaaa cgcattctta gccacgtcgc cgtccttgaa
    25021 ggcgcgccgc cgctctcgga acactggacg cttttcgaca ataacgaagc gctattcaac
    25081 gacgcgcgca cggcgcaggc cgcgacaatt attttttcgc ttacacagaa caaccaaatc
    25141 gaaccgcttg ctcgtcgcat tcatactttg cgacgccagc ggggaagcgc gctgaaaatt
    25201 gtcgtgcgcg aaaatatcgc cagtttgcgc gccaccgatg agcgcctgct gctgggctgc
    25261 ggcgcgaata tgatcattcc ctggaacgcc ccgctttcac gctgtctgac gcttattgaa
    25321 agcgtgcagg ggcagcagtt cagccgttac gtaccggaag acatcaccac gctactgtcg
    25381 atgacgcaac cgttgaaact gcgcggtttt cagccgtggg ataccttttg cgatgccatc
    25441 catacgatga tgagcaacac cctgctcccc gccgacggga aaggcgttct ggtcgcgctg
    25501 cgcccggtgc cgggcattcg ggttgagcag gcgttaacat tatgtcgacc aagccgaacc
    25561 ggcgatatta tgaccatcgg cggcaaccgt ctggtgctgt ttttatcatt ctgccgggtc
    25621 aacgatctgg ataccgcgtt aaaccatatt ttccctttgc cgacaggcga tattttctct
    25681 aatcgtatgg tctggttcga agataaacaa atcagcgccg agctggtgca gatgcgctta
    25741 ttgtcgccgg aactgtgggg aacgccgcta ccgctggcaa aacgcgccga cccggtaata
    25801 aatgccgaac acgatggccg catctggcgt cgtattcctg aacccctgcg attgctcgac
    25861 gacaccgcgg agcgtgcatc atgatgacca tcagcgatat cgtgcaaatt attctttttt
    25921 gcgcgctgat tttctttccg ctggggtatc tggcgcgtca ttcgctacgc cgtatcagtg
    25981 atacgacccg gctgctattt gccaaacctc gttatgtaaa accagccgga actctgcgcc
    26041 gcgctacgaa agtcaaggca gacaaaaaat gactcagcat actcaaactc cttcaatgcc
    26101 ttctccgctc tggcaatact ggcgcggtct ttccggctgg aacttctatt ttctggtcaa
    26161 gtttggcctg ctgtgggcag gctatctgaa ttttcatcct ttactgaatc tggtattcat
    26221 ggcgtttctg ctcatgccaa taccaaaata tcgccttcac cggttgcgcc actggattgc
    26281 cattcccgtc ggcttcgcgc tgttctggca tgatacctgg ctgcccggcc cgcaaagcat
    26341 tatgagccag gggacgcagg tggcggaatt cagctccggt tatctgctcg atctgatcgc
    26401 ccgttttatt aactggcaaa tgatcggcgc catcttcgta ctgctggttg cctggctatt
    26461 tttatcacag tggattcggg ttacggtgtt tgtggtcgcc atcatggtat ggctgaatgt
    26521 cctgacatta accggcccgg tttttacgct gtggccggca ggccagccaa ccgatacggt
    26581 gacgacgact ggcggtaacg cggccgctac cgtcgcgaca gcgggcgata agccggtcat
    26641 cggcgatatg cctgcgcaaa ccgcgccgcc aacgaccgcg aatctgaacg cctggttgaa
    26701 caccttctat gccgcggaag aaaagcggaa aacgacgttc ccggcgcagc ttccgcctga
    26761 tgcgcagccg ttcgacctat tggtcatcaa tatttgttcg ctctcctggt cggatgtcga
    26821 agcggcaggc ctgatgtcac atccgctatg gtcgcacttt gacattttgt ttaaacactt
    26881 taattccggt acgtcttaca gcggcccggc ggccattcgt ctgctgcgcg ccagctgtgg
    26941 tcaaccttcg catacccgac tttatcaacc agccaataac gaatgttatc tgtttgataa
    27001 tctggcgaaa ctgggcttta ctcagcatct gatgatggat cataacggtg aatttggcgg
    27061 cttcctgaaa gaagttcgcg aaaacggcgg tatgcagagc gaactgatga accagtccgg
    27121 cctgccaacc gccctgctgt cattcgacgg ctcgccggta tatgacgatc tggcggtcct
    27181 gaaccgctgg ttaacagggg aagaacgtga agccaattcc cgctccgcga ctttctttaa
    27241 cctgctgccg ctgcacgatg gcaaccactt ccctggcgtc agcaaaacgg cggattataa
    27301 aatccgcgcg cagaaactgt tcgatgaact ggacgccttc tttaccgaac tggagaaatc
    27361 cgggcgtaag gtgatggtag tcgtcgtacc ggagcacggc ggcgcgctga agggcgacag
    27421 aatgcagatc tcaggcctgc gcgatattcc cagcccctcc atcaccaacg tcccggcggg
    27481 cgtgaaattt tttggcatga aagccccgca tgagggcgcg ccgattgata ttaatcagcc
    27541 gagcagctac ctggcgattt ccgaactggt cgtacgcgcc gtggacggta agctctttac
    27601 cgaagacagt gtgaactgga acaagctgac cagcaatctg ccgcaaaccg cgccggtttc
    27661 agaaaacgct aatgcggtgg tgattcagta ccagggtaag ccctacgttc gtctgaatgg
    27721 cggcgactgg gtgccttacc cgcagtaaac cgaaaaaggc cgcaaggttt cccctgcggc
    27781 ctggctcggg cgcatgttgc cattacggcg gacagacgct caaaacgcgt tacttcctgt
    27841 cacgtagcca gttgacgatc acactggcga taatgccagc aatgatcggc gccgccagat
    27901 cgtgccagaa ggccacgccc aactgcgtaa gcgtcatata gccgccttgt tgcaatggca
    27961 accgttcgcg gctatcttta aagtgtttgg gttcaagtta gcccccgtca ggttgccagg
    28021 tttataccag tcaacgtgcg ggggttttct ctatccagca acctatgccg ccggggctca
    28081 agcccccgca acattgcgcc tcaccgggta aacccggctt gctgctgata ttacggcaaa
    28141 atccccgtcc cggcacggcg ctaacgtgca atctgcgtga cgcttcgcag acgactactt
    28201 ttatttgcca gaatacattc agcatttctg aggctggcag tcagccgctc aattctgtaa
    28261 attatgcctc ctcgcggcca gtcccggtga taccgaaacc ctcgttcagc atcctgcgtc
    28321 tatgacatat tcgcctgttg cgccagagga atggctaaaa gcaggtatta ccgacgaact
    28381 tatccgtctt tcagcgggac ctgaagatcc cgacgatatt attcatgacc ttgaacgcgc
    28441 cagcagaaaa gcagcattct gacgattgct cggcgaaccg ctgtcaccgg tttgccgcat
    28501 cgggtatcaa ggcactatag cctggttata ggcagcattc tttatgagag agctgcgtat
    28561 attttgggca gggggctcta tgcaggacga cacattacca ttaaataaca gtaacgctac
    28621 gaccacaccg ctttcaacga gattaccgtt tacaaaatat gattttggct gggtgctctt
    28681 gtgtatcggt atggcaatcg gcgccggtac cgtcttaatg ccagtgcaaa tcggtctcaa
    28741 ggggatctgg gtatttatta ccgcttttat catcgcctat cccgctacct atattgtgca
    28801 ggatatttat ctaaaaacgt tatctgaaag cgaaacctgt gacgattata cggatattat
    28861 cagtcactat cttggcaaaa actggggcgt ttttctcggt gtaatctatt ttcttatgat
    28921 tatccacggg gtgtttattt actccctgtc ggtggtgttt gatagcgcct cctatatcaa
    28981 aaccttcggc cttactgagg ccgatctttc gcagtctatt atctataaag tcgcgatttt
    29041 cgccgtgctg gtggcgattg cctccggcgg ggaaaagcta ttatttaaaa tttccggccc
    29101 gatggtagtg gtaaaagtcg ggatcattct gatattcggt ttggcgatga tcccacactg
    29161 gaatcttgat aatatttccg cctttcccgc cgcatcggtt ttctttcgcg acgtactgct
    29221 cactatccca ttttgcttct tttctgcggt cttcattcag gtgctaaacc caatgaacat
    29281 cgcctatcgt aagcgcgaac ctgaccgtgt gctggccacc cggatggcga ttcgcacgca
    29341 tcgcattagc tatattacgc tgattgccat tattctcttt ttctcgtttt cgtttacctt
    29401 ttcgattagt catgaagagg cggtatcagc gttcgagcag aatatttccg ctcttgcgct
    29461 ggcagctcag gtaatccctg gccagatcat ccacattacc tctaccatcc tcaatatttt
    29521 tgccgtactt accgcgttct ttggtattta tttaggtttt cacgaagcgc ttaaaggtat
    29581 tgtactgaat gtgttgagtc gcattatgga tgtcaaaaac atcaacccac tgttactgac
    29641 atctggaatc tgtgtcttta tcgtggttac tctggttatt tgggtttcgt ttcgcgtctc
    29701 agtattggtc tttttccagt taggcagtcc gctttatggc attgtcgcgt gtattattcc
    29761 ctttttcctg atttataaag tagcgcaact ggaaaaatta cgcggcctga aaacctggct
    29821 tattctgtta tatggaatat tgttgtgcct gtcgccgtta ttaaaattga ttgaataaga
    29881 gcctatccca ccaggcgtta ttggcacagc cagtttggac acggacagcg cgcaaaaacc
    29941 ggagcgtaca cgtagtacgt gaggtttgac tcgctacgct cgcccttcgg gccgccgcta
    30001 gcggcgttca aaacgctaac gcgttttggc gagcactgcc caagtccaaa atggcaagta
    30061 aaatagccct aatgggatag gctctaagtc gtaccggaga gccatgcccg gtggcgctac
    30121 gcttaccagg cctacaagta aggtgtaggc ttgataaggc gcagccgcca tccggcataa
    30181 aacgcaatta actcagcggc ttctgcgggt tttcatcctg atcgacggca aagcaggcca
    30241 ccaactggcc gtcgtactct ttaagctgcg gctgtaactg cgtacagggt ccgaagcgac
    30301 ggcggcagcg ggcgttgaag gcgcagcccg gcggcgggtt cagcggactc ggcaactcgc
    30361 cggtcagctt aatccgctca cggcgatcgt ccggattcag ccgcggcgtg gcggagagca
    30421 acgcttgggt atagggatga cgtggattgt taaaaatctg ctctttggtc cctttctcca
    30481 cgcagcggcc taagtacatg accattactt catcggcaat gtgctccacc accgacaggt
    30541 cgtgcgagat aaagacataa gacagcccca tatcctgttg caaatccatc atcaggttca
    30601 gcacctgagc gcgcaccgac acgtcgagcg cggagaccgg ttcgtcggca atcactacgt
    30661 ccggatcaag catcagaccg cgggcgatag cgatacgctg acgctggccg ccggagaaca
    30721 tatgcggata gcggtcgtag tgctcggttt tcagccccac cttcgccatc atcgccagcg
    30781 ctttttcacg gcgctgctct ttgctgagcg aggtgttaat cagcaacggt tcttccagaa
    30841 tttgccccac tttcttgcgt gggttcaggg aaccgtaggg gttctgaaac acaatctgaa
    30901 ttttctgccg ccgcagtttc tgcgcgtgcg gatcgtgttt gagcagatcc tgcccctggt
    30961 aataaagctc gccgccggtt ggcgtttcaa ccatcgtcag caggcgaccc agtgtggatt
    31021 ttccacaacc ggactccccc actaccgcca gcgttttacc gcgttcgaga ttaaacgaca
    31081 cgccgtccag cgcttttacc agccgttccg gagaaaagat ccccttcttc accggatagt
    31141 gttttttcag gtcgatagcc cgcaacagcg gctgttgcaa ggtggcctca tgcgtactca
    31201 tagtgtgggc ctcccggcat catcgagtgg gtaatgacat tttgactgac gtccatcgtc
    31261 cagttggttg agagcaggtt cttccgcacg acatctgtcc gtggcgtggg ggcagcgagg
    31321 gttaagcaga caacccgtcg gtcggtcata tttccccggc accacgcccg gcagcgacgc
    31381 cagacgcgct ttatcttgcg caaactctgg taacgcacgt agcaatgcct gggtatacgg
    31441 atgacgcggc gcgcggaaaa tatcctgcgc agcgccggtt tcgacgacct gcccggcgta
    31501 catgacgata attttgtgcg ccgcttccgc caccagcgcc aagtcatggg taatcagcac
    31561 cagcgccatg ttctcttttt gctgcaactc cagcagcagc tcaatgattt gcgcctgaat
    31621 ggtcacatcc agcgccgtgg tcggttcatc agcaattaac agctttggtc gacaggctat
    31681 ggccatcgca atcatcacgc gctgactcat gccgccagaa agctggtgcg gatagacatc
    31741 cagacgagaa gccggatcgg gaatacccac ctggttcaac aggtcaatcg ctcgctgacg
    31801 acgggttttc ttgttcccgc cctgatgtac cttgatggct tccataatct gaaagccaac
    31861 ggtatagcaa ggattgaggc tggtcatcgg gtcctggaaa atcatcgcca cttcagcgcc
    31921 caccaggttg cgacgttcct tctcggaaat gcgcttcaga tcctgtccgt taaagagcag
    31981 gttttccgcc atcacgcggc ctgggtaatc gataagcccc ataatcgcca gcgagctgac
    32041 ggatttgccg gaaccagact cgccgacaat accgaccacc tcaccctgct tcacgctgta
    32101 gctaatgcgg tcgacggctt tgaacggtgt cccttcgtcg ccgaagtgca ccgataattg
    32161 atctacattt aataacgcca tctcgaacct cttactgctt cagtttggga tcgagcgcgt
    32221 cacgcagacc gtcacccatc aggttaaatg ccagtaccgt cagcagaatc gccagccccg
    32281 ggaaggtcac gacccaccag gcgctttgcg cgaactgcaa tacatcagag agcatggtgc
    32341 cccattccgg cgtaggcggc tgcgcgccca tgccaagaaa gccgagggcg gccatatcga
    32401 gaatggcgtt agagaaaccg agcgatgcct gaacgatcag cggcgcaagg cagttcggga
    32461 aaatattgac gaacatctga cgcatcgcgc ctgcgcccgc cacgcgggag gcagtcacat
    32521 aatcgcggtt cacctctacc agaaccgccg cgcgggttaa gcggacatag tgcggcagcg
    32581 ccacaaacgt caacgccagc gcagcgttgc cgatggaggg gccgaagatc gccaccagca
    32641 ccagcgccag cagcaggctc ggcagggcca gcataatatc gaccacgcgc atgatgatgt
    32701 tatcgaccag accgccgaag tagcccgcga ctaggccgag aataatcccc atgaccagcg
    32761 acaggacgac caccagacag ccgaccagca gcgacaaacg cgcgccatac atcaggcgcg
    32821 agagggcatc gcgaccaaca tcatccgttc ccagaatatg cgcccaactg ccgccttcct
    32881 gccagaccgg cggcgccagc agcgcatcgc ggaactgctc tgccgggttg tacggcgcaa
    32941 taaagttggc aaacaccgca atcaggatca cgatgagaac atacgccagc ccgacgaccg
    33001 cgcctttatt gcgtttgaaa tagtgccaga actcccgcaa tggcgtcatg ggcgccggtg
    33061 cggcattaac attattttca gtaacctgtg acatgatggc cccttacttc ttatgccgaa
    33121 tacgcgggtt caccacgccg tacagcaggt ctaccagcag gttgacgaga ataatcatcg
    33181 tcgctaccag taacacgccg ccctgcacta ccggataatc gcggcgttgc agcgcatcga
    33241 tcagccagcg ccccagaccg ggccacgaga agatagtttc tgtcagaatc gcgccagcca
    33301 acagcgtccc gacctgcagg ccgatcacgg tgacgactgg cagcatggcg ttacgcagag
    33361 catggacgat aatgacgcgc atcctggtca accctttggc gcgtgcggta cggatgtaat
    33421 cctcccccag cacttccagc atcgacgaac gggtcatacg cacaatgacg gccagcggga
    33481 ttgtgccgag caccatcgca ggcaggatca tatgcgccag cgcatcaata aagttaccct
    33541 cttcgcccca gatagcggtg tcgatcagca taaagcccgt caacggattg gtatcatcaa
    33601 ggaacaccat atcgctcacg cgcccggaaa ccggcgtcag gttccagtgg acggagacca
    33661 gcatgatcag catcatgccc caccagaaga taggcataga gtaaccggtc agcgccaggc
    33721 caacggcagt gtgatcgaag atagaaccgc gcttcactgc ggccagcacg cccaccggaa
    33781 tccccacggc gacggcaaaa atcatggcgc agacgccaag ttccagcgtc gctttaaagc
    33841 gaggtacgaa ctcgtcccac acggggattc ggcttttcag cgagatgcct aaatcgccat
    33901 gcatcacccc ccagatataa tggaggtact gctgccacat cggtttatca agaccgagtt
    33961 cagccagcag ttgagcatga cgctcagggg aaatacctcg ctcacccgcc atgatcatca
    34021 ccggatcgcc ggggatcatg tggacaaagg caaaggtgag aagggtaata ccgataaacg
    34081 tcgggataac gagtcccaaa cgtcggagaa tgaactgcaa cataacccga attctctctc
    34141 atgacgcacg gcctggaacc gtgagtctgt attgctcaca aatcttatcc cacgcaaact
    34201 gcatcgcgga taaagcatta cgccggatgg cgctgcgctt atccggccta cacaacaccg
    34261 gggcgcagcg ctcttttaat tattcgacag agacgttttc gaagtgatgt ttgcctaatg
    34321 ggtcaaccac atagccttta acttctttac gtactggctc ataaaccgtg gagtgagcga
    34381 tgatcagcgc tggcgcctgg tcatgcatca caacctgggc ctgtttatag agttcaatac
    34441 gcttgttgtg gtcatcggtc gcacgcgcag gctgaatcag gtcttcaaac ggcttgtagc
    34501 accattttga atagttggag ccttgctggg cggcatcgca gctgaacagc gtggcgaaga
    34561 agttatccgg atcgccatta tcgccggtcc agcccatcat caccgtctgg tgctcgccat
    34621 ctttagcgcg cttgaggtat tcgccccatt cataggtgac aattttggcc tgaacgccaa
    34681 tcttcgccca gtccgcctgg atcatttccg ccatacgacg cgcattcggg ttatagggac
    34741 gctgtaccgg catcgcccat agatcgatgg tgaagccttt ttccagaccg gcttctttca
    34801 gcagcgcctt cgctttttcc ggatcgtagc cgtagtcttt aatatcgtcg ttgtagcccc
    34861 acatcgtcgg cgggatcagg tttttcgccg caacgcctgc gccctgataa acggctttga
    34921 tgatggcctc tttattcacg gcataggtca acgcctggcg aactttgacg tcatccagcg
    34981 gttttttctg cacgttatag gagagataac ccacgttcag accggcctgc tccatcaggt
    35041 tgatgttttt atcttctttc atgcgcgcaa tatccgccgg gttcggatac ggcatcacct
    35101 gacattcgtt cttctgcagt ttggcgtaac gcacagaggc gtcaggcgta atggagaaaa
    35161 ccaggcggtc aattttcggc ttcgtgcccc agtagccgtc aaaggctttg tagagaatgc
    35221 gggaatcttt ctgatattgc accagttgga atgggccagt gccgaccgga ttcagatcca
    35281 ctttttccgg cgtaccggct ttcagcatgt tgtcagcata ttctttggaa agaatagagg
    35341 cgaagtccat ggctaaatcg gcaaggaacg gcgcttccgg acgcgtcagc acaaactgca
    35401 ccgtgtgatc gtctaccttc ttcacttcgc taatcagatc cggcagcccc atgccttcaa
    35461 agtattcata gctgccgcca gacactttat ggtacgggtt ctgctcgttt ttctgccggt
    35521 caaaagagaa cacgacatca tcggcgttca gctcgcgcgt gggtttgaaa tccttgctgg
    35581 attgccattt caccccttta cgtaggtgga acgtataggt tttaccgtct tcgctgatat
    35641 cccacttctc agcaagaccc gggatcactt ccgtggtgcc ggttttgaat tcaaccagac
    35701 ggttatagat aggtacggag ctggcatcat aggtggtgcc agacgtaaag agctgtgggt
    35761 taaagccttc cggcgagcct tctgaacaat aaaccagggt tttggcctgc acgcttgctg
    35821 caacggtcat ggccaccagg ctcaaaccaa gcttcagcat ccctgacttc ttcaaggaaa
    35881 tactcattct tctgctccaa ttgtgatgta tgttgttttg ccctttgcaa agacttttac
    35941 cgctcggcct tttttgtttt ttacctggtc aggtcagtag tgagaggtgg ggattccgtt
    36001 cgcataatcg actgagttgc agtgcggatt ctccataaaa tgcccctcat tccctacaat
    36061 ctgtcaatag aatgtcaaaa cgtcaataca ggtaaccagc ttttacaaca acggtgagaa
    36121 ttaacaaaca aagattaaaa aaagttcaga agggtatttt cagcagggaa atttgtgcta
    36181 caggcagaaa ggcagagtta ttcacttaat attttgcaac agttagtgat taacaattag
    36241 ccattaattg aaaaatttct ttcgatatgt tgattatctg agcgattaat accactaacg
    36301 ctaaaacgca caggcgaaaa tgctgaggtt atccataagc cgtgtgcaaa gaagagtgat
    36361 ccggacattg aaaaacacca tcgaatatgt tacaaaattg taaataagta ggccgtcgtg
    36421 cggcctaccg cgatcacaaa aactaacttt tggccctggc ctgcgtgcgc ttttcgctcc
    36481 agttaaacaa cgagttcacc agaatcgccg tcaacgtccc cgctgccatg ccgttgccaa
    36541 agaccatctg tacgcccgcc gggaaattct gatacaggcc gggtaccagt ataggtagca
    36601 ttcccatggc cagccccatc gccagcgcgt aggttttacc cggcgtatgc agtggctcac
    36661 gcgcaatcat atcaatgccg ataaccccga taatgctgaa gacaatcacc gccgtaccgc
    36721 acaccaccga acctggcaga caggtcgcca gacgtaccag cggcgcgaat atggcaatca
    36781 ggattaacaa tcctccggca gccgcagtca cgaaacgcga tttcacgtta gtggtgcgta
    36841 tcaccccaat attttcgccg gaggtgataa ttaaggaggt gccaaaaatc cccccagcag
    36901 cgacattacc gcatcaccac gaatggtacg tggaatcgcc tgttgcacat tttgcgtgga
    36961 attgactatt tccgcggtcg caatcgtttg cccagttgct tcagccatag agatgaccgc
    37021 gtaaatcagt aaaggcagcg aggcggagag atcaaaaatc ggccagccga acggcaaaag
    37081 ctgtgggaaa ctaaacagcg gcccgtgact aacaccgcta aaatcggtgc tgcccagcgc
    37141 cattcccagc agcgtccccg ctaaaaggcc gaacatcacc gccagctggc gcaaaatacc
    37201 gctaaacgcc agcgcgaaaa tcagcgttat caggatagtc cccagcgata aaatgatact
    37261 ggttggatga gcgaagtcgg cgctccctgg ctggccaatg atcaacccgc cgtacaggcg
    37321 aataaggtta atcgacacca ttagcagcat gatgccaatg ataaaggggg gaaaatggtg
    37381 caggcagcgg cggaaaatcg gcaacgcgat aaagtagaac agcgaggtca gaattacggc
    37441 gccaatcgcg gtctggatat tggtctgtaa agcgatcgca acgaaaatcg caatcggcgc
    37501 gccccccggt accataataa acggcaaacg cgcgcccacc cctttcacac ccaggctttg
    37561 cagaatagcg cccagaccgc acatcagaaa ggtcgcgcta agtaccgagg cggtcaccgt
    37621 atcggtaaag tggagcgctt tggcgatcag aaagacggag gtaatggggg tggcggcaac
    37681 gaccagcaca tgctgaagcg ccaaaagtaa ggtggtttgc cagggtaatg catcgttatc
    37741 cggcgtagta aggccaggct gcggcatgat taactcccat aaaacatcaa aaaaataacc
    37801 gccagcgcgg gctggcggtc tgcattattt caaccaacta atggcatcag cggcatagcg
    37861 atgcgcacgg aaggcgctgt tctgttttcc aggaataatg cctttactga ggtgctccgg
    37921 atattcatta aagaacggaa tgatatattc ccataccgtt tcgccttccg gggtaacttc
    37981 aaacaggcgg ccaaacgccg attcacagat aaaggtgttg ccgttcgcca gccgctgcgc
    38041 gctccccata tacggcgaga aaaacgccgg cgggaagata tcgcgatact gccaggtaat
    38101 cgctttgatc tgcggatcga actccagcac cgtggaatgc ggcgaggtga cgccgggacg
    38161 caggttgccg ttatcgaaaa ccagaatcga cccgttctcc atctcaaccg gcgtgtgctg
    38221 ctgcgctacc acttccggcc ctgcatgcca gataaccttc ccgctctctt tatccacggc
    38281 aatgacgccg gaagtggtac gcaggctcat cagtaccagg ccatcacggg tgacggacag
    38341 gccgttaatc atcggccagt ggcggcggtc gaaaatatca tgaatcggga aatcttccgg
    38401 attcaaatgc tcccaggcac gccattccca caccacttca ccgtcgcgat tgacctcttt
    38461 gacgacgtcg ctctgaatca cgccgtccgg cgcatcgcgg cgcgggtcgc cgccggtaac
    38521 acgggcggcg atatcggcag gtaacggcga cgcggcggta tacagcagat taccgttcgc
    38581 caaccattgc gcatcatggt gatggtaaat atcttcgtaa tgccagacga tttcgttatc
    38641 cggcgtcact tcgtagaagt cgccgccgtg ccagagatcc cacgccggat agaggttcgc
    38701 tgaagtgcgg tggctgccgt tataacccag attaccgttc ggcagcagca ccgcatcacg
    38761 cccggcgcga accggaagct gccactgatg cgcgacttcg ccctgctcgt ccaccaggta
    38821 aacccgccct tcggcggttt gcggcgcaaa aagcgtatag ccgccaaagc tcttcgcctt
    38881 atcagcgtag ataaggcccg ccggacggcg tccaagggtg aaagtcgaat cctgagttaa
    38941 gtgtgccaca tcgcctcctg aggaatagat ttgcgccaaa atactccatt aaaacgtttt
    39001 aatgaagagt tttttacgat caccaccgaa aaaaagcaaa cgttaccgtc tggtaaatat
    39061 gctaccctgt gcgcaaattt tcgcaggtca ggaagcagat ggctgttcaa aataaaaaac
    39121 gcgcaaagtt gattgatgtt gcccgccatg caggcgtctc gccagggacg gtatccaatg
    39181 cattgcacaa cacccgcttt gtcgagccgc agacgcgacg gcgtattgaa gaggccattg
    39241 ttgcgctcaa ctacacgccg aatattcgcg ctcgccagtt acgaaccggc aaaaccaata
    39301 ccattgcttt gctctcttcg gtgccgctgg cgattgcctc cggcgcatca cgactgggat
    39361 ttatgatgga ggtggcgtta acgtccgcga tgatggcgct ggaaaaacag catgcgctga
    39421 ttctggtgcc accaggggta aatccactgg atgccgtcag ctttgacgcg gcgatcctga
    39481 ttgagccggc ggagaacgac ccgcagctcc aggcgctggc gcaagcgggc attccctgcg
    39541 tcaccattgg ccgcacgccg gggaccgaca cgcctgtgcc gtgggttgag ctgcactcgg
    39601 cggcaacagc acagcttctg ctaacgcatc tggaggcctc cggtgccagc aaatgtgcgt
    39661 tatttgtcgg taacacacgg cgaacatcag ttctagagag cgaagcggct taccagcgct
    39721 ggtgcgcggg gcgccaggac cccgtcgtct actctctcaa tgaaagcgag ggtgaaaatg
    39781 ccggctacca ggccgcgcag cagctattac aggcgcatcc cgacgttgac ggcgtgctgg
    39841 tgctgataga tacctttgcc agcggcgcgg tacgggcttt ccaggaacaa gacatcgcca
    39901 tacctgaaca aatacgggtg gttactcgct atgacggtat ccgcgcgcgc gaatcgctgc
    39961 cgccgctgac ggcagtgaat atgcatcttg atgaggtggc gcgacaggca atcacactcc
    40021 tgtttgccgt tctgtcgggt gagaaggtca gctacagcga cgggatcatg cctgaactgg
    40081 tggtgcgagc gtcaacctgc cggtgacaga ggatgacttg ccactgcggg ccgttgctga
    40141 cgcaacgttc tctcgcttcg ctcgagtcga acctcttgcc cccggaggtt ctcatcctcg
    40201 tcaggcttca gatacaaaaa accctgctcg ctgagcaggg tttctgaatt tggtcggtga
    40261 tagaggattc gaacctccga ccccttcgtc ccgaacgaag tgcgctacca ggctgcgcca
    40321 atcaccgaat gcgggcgcat cttactgctc aggcgcacgc ccgtcaatcc cttagtcgca
    40381 aaatacaatt caatcggcga gaaagtcggc agacaaccta cttcgcggcg actttctgcg
    40441 catcgggaat atggcaccag ttgttgttct ggttaatgcc gccattcggc gatgtatacc
    40501 ccaggcagcc cattatcgta tcgtacagtt ccacatgacg acgcggcact ttgatctccg
    40561 cctgctgttt caggtgagcg gacatctgcg catgttgcgg actggcaaga tatttatccg
    40621 acatccatac cagcatcgga acacggaatt gctccggcgg cgccatattg cgcggcgtac
    40681 cgtgcaaatg ttcgcgttcg ttaatcgact cgccgtggtc agccgcgtag aacacaatcg
    40741 cttttttatc acgtagctga tcgaacacac tggtaataaa gtgatcaaca taggtcacgg
    40801 agttatcgta agagttgatc atctgcgctt tcgtgcagcc gctatcgacc ccaatacatt
    40861 cgggcttcca ttgagcgtag ctgcgcggat aacgctgcgt atagttaaaa tgcgatccct
    40921 tggtatgcag gataatcaga tgcttaccct ccggattctg ggcaagcgag ttctgcatct
    40981 catcaatcaa cagcatgtca tccaccgttt taccgcggtt acgcggctcg gcgccaatct
    41041 gctcgcggta agagatatta tccgccatgg tattgctata gaaccacatc tcgctctgca
    41101 tggcgtacag atcggaactg aatccgagct gtttgagtac ggcaaaaaca ttctgctctt
    41161 ttaacgtacg ctgcgggtta ttatccgccc caccttcccg tacaaacata cagcgtaaag
    41221 aaagcttcgg cgtggtatta cgctcgtagc cgaaaatccc catgtgatcc caacgggtcg
    41281 tctcaccgat aatgaaaacg acgtaggtgt catccccatc tttcggcgca acataggtaa
    41341 atttcctggc cgggtttatt aacgaattat tgtccgacga ctcatctacc tgcgcccagg
    41401 catacagccc taacgcagat aaccagtttg agggcaggta ggagttcgcc accacgccgc
    41461 catagctggg taagtcgatg cctgtcgccc gttcaaactt tttctgctgt acatccagca
    41521 ggcggatagg cgcccacacc attacgcctg cgagtatcac tacagcggcg ctgcgaaaac
    41581 gctgccccgg cgtacgtagc tggcgcaaca acgtgtagcg acagtggtta ctccagataa
    41641 agatgagcgg aagcacgctc acggcaatca gccacaatac aaagtgcagc cccaccacct
    41701 ctttcgagag atcgatatcg gtggtcataa cagacgcaat aatgccgtag ccaatcacca
    41761 cgttcaggaa ggtcatgtaa taactggcgc cagcggaaaa cagcaccacc agcgtggcca
    41821 gcacgcgcca gacgcgtcgg ccaaacagtg aaagaagacg aagtaagaag aaagtgacca
    41881 gcaccgtggc gccaagttcg acaactgcgg aaaggccttt ccaaatggta aattcttgcg
    41941 cataactgcc gaaacggcgg taaaacacgg cgcaattcat aaacagaccg atatagagcg
    42001 caagcaagaa actaagtttc tgctgcgtca tcgatttaat gtatctcatg caaacaaacc
    42061 ctgggaatcg ggataaaaac gacctgtaca acgattcttt aatcaaacag gtaaatatgc
    42121 ggctaacgca gatgtgagaa agtctaccag cgcggctaag tagaccacag gaagcgcaaa
    42181 aagtgtctat a
//
LOCUS       DAJVBX010000013        40338 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.013, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000013 DAJVBX010000000
VERSION     DAJVBX010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 40338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40338
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.013"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(77..439)
                     /locus_tag="OPV72_000636"
     CDS             complement(77..439)
                     /locus_tag="OPV72_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibL family ribosome-associated protein"
                     /protein_id="HCR9913012.1"
                     /translation="MKEVEKNEIKRLSDRLDAIRHQQAGLSLVESADKYAELEKEKET
                     LEAEIIRLREVHSQKLSKEAQKLMNLPFRRAITKKEQADMGKLKKSVRGLIVVHPMTA
                     LGREMGLKEMTGFAKSEF"
     gene            730..936
                     /locus_tag="OPV72_000637"
     CDS             730..936
                     /locus_tag="OPV72_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913013.1"
                     /translation="MAKIGENVPLLIDKAVDFMASSQAFREYLNKTPPRDYVPSEVPS
                     ESTPIYLQRLEYYRRLYRPKEERG"
     gene            complement(946..1536)
                     /gene="mtlR"
                     /locus_tag="OPV72_000638"
     CDS             complement(946..1536)
                     /gene="mtlR"
                     /locus_tag="OPV72_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol operon repressor MtlR"
                     /protein_id="HCR9913014.1"
                     /translation="MTQNPAQVSLRPNNRLSDMQAIMEQTQAFENRVLERLNAGKTVR
                     SFLITAVELLTEAVNILVLQVFRKDDYAVKYAVEPLLDGDGPLGDLSVRLKLIYGLGV
                     LSRTEYEDAELLMALREELNHDGNEYAFTDDEILGPFGELHCVMALPPPPHFDTSDAA
                     LYAMQIQRYQQAVRSTMVLSLTELISKISLKKAFQK"
     gene            complement(1533..2681)
                     /gene="mtlD"
                     /locus_tag="OPV72_000639"
     CDS             complement(1533..2681)
                     /gene="mtlD"
                     /locus_tag="OPV72_000639"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HCR9913015.1"
                     /translation="MKALHFGAGNIGRGFIGKLLADAGIQLTFADVNQVVLDALNARH
                     SYQVHVVGENEQVDTVSGVNAVSSIGDDVVDLIAHVDLITTAVGPVVLERIAPAIAKG
                     LVKRKAQGVDAPLNIIACENMVRGTTQLKGHVMNALADGDKAWVEQHVGFVDSAVDRI
                     VPPSASATNDPLEVTVETFSEWIVDKTQFKGALPNIPGMELTDNLMAFVERKLFTLNT
                     GHAITAYLGKLAGHQTIRDAILDEGIRAVVKGAMEESGAVLIKRYGFDADKHAAYIQK
                     ILGRFENPYLKDDVERVGRQPLRKLSAGDRLIKPLLGTLEYGLPHVNLVKGIAAAMHF
                     RSDEDPQAQELAALITEKGPQAALAQISGLDANSDVVAEAVNAYNATK"
     gene            complement(2902..4818)
                     /gene="mtlA"
                     /locus_tag="OPV72_000640"
     CDS             complement(2902..4818)
                     /gene="mtlA"
                     /locus_tag="OPV72_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HCR9913016.1"
                     /translation="MSSDIKIKVQSFGRFLSNMVMPNIGAFIAWGIITALFIPTGWLP
                     NETLAKLVGPMITYLLPLLIGYTGGRLVGGERGGVVGAITTMGVIVGADMPMFLGSMI
                     AGPLGGYCIKKFDSWVDGKIKSGFEMLVNNFSAGIIGMILAILAFLGIGPAVEVLSKI
                     LAAGVNFMVAHDMLPLASIFVEPAKILFLNNAINHGIFSPLGIQQSHEMGKSIFFLIE
                     ANPGPGMGVLLAYMFFGRGSAKQSAGGAAIIHFLGGIHEIYFPYVLMNPRLILAVILG
                     GMTGVFTLTILNGGLVSPASPGSILAVLAMTPKGAYFANIAAIVAAMAVSFVVSAILL
                     KTSKVKEEDDIEAATRRMHDMKAESKGASPLAAGDVTNDLSHVRKIIVACDAGMGSSA
                     MGAGVLRKKVQDAGLSQISVTNSAINNLPPDVDLVITHRDLTERAMRQVPQAQHISLT
                     NFLDSGLYTSLTERLVAAQRHNTNEEKVRDHLKDSFEEGDNNLFKLGAENIFLGRKAA
                     NKEEAIRFAGEQLVKGGYVEPEYVEAMLDREKLTPTYLGESIAVPHGTVEAKDRVLKT
                     GVVFCQYPEGVRFGEEEDDIARLVIGIAARNNEHIQVITSLTNALDDESVIERLAHTT
                     SVDEVLELLAGKKA"
     gene            5293..5901
                     /locus_tag="OPV72_000641"
     CDS             5293..5901
                     /locus_tag="OPV72_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase"
                     /protein_id="HCR9913017.1"
                     /translation="MKLIGSYTSPFVRKISVLLLEKGITFEFINELPYEADNGVAQYN
                     PLGKVPALVTEKGEYWFDSPIIAEYIELLDIAPAMLPRDPMAALKVRQLEALADGIMD
                     AALVSVREQARPAAQQSETELLRQREKINRSLDMLESYLSDGTLKTDTVNLATIAIAC
                     AVGYLNFRRVAPGWCVSRPHLVKLVETLFQRESFARTEAPKA"
     gene            6000..7391
                     /gene="selA"
                     /locus_tag="OPV72_000642"
     CDS             6000..7391
                     /gene="selA"
                     /locus_tag="OPV72_000642"
                     /EC_number="2.9.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-seryl-tRNA(Sec) selenium transferase"
                     /protein_id="HCR9913018.1"
                     /translation="MTSETRTLYSQLPAIDRLLHDSAFLSLRDRYGHTQVVDLLRRML
                     DDARDVIRNTQTLPDWYADWAQEAKLRLENAAQSALRPVINLTGTVLHTNLGRALQAQ
                     EAIEAVTQAMRAPVTLEYDLDGAGRGHRDRALATLLCRITGAEDACIVNNNAAAVLLM
                     LAATASGKEVVVSRGELVEIGGAFRIPDVMRQAGCTLHEVGTTNRTHAKDYRQAVNEN
                     TGLLMKVHTSNYSIEGFTKTVEEAELAEIGRELDIPVVADLGSGSLVDLSQYGLPKEP
                     MPQQLIAAGVSLVSFSGDKLLGGPQAGIIVGKKAMIAQLQSHPLKRALRADKMTLAAL
                     EATLRLYLHPEALAEKLPTLRLLTRSEASIREQAQRLQARLAARYGDEFALEVKPCLS
                     QIGSGSLPVDRLPSAAMTFTPHDGRGSRLEALAARWRTLPVPVIGRIYDGRLWLDMRC
                     LEDESRFMEMMLK"
     gene            7388..9238
                     /gene="selB"
                     /locus_tag="OPV72_000643"
     CDS             7388..9238
                     /gene="selB"
                     /locus_tag="OPV72_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenocysteine-specific translation elongation
                     factor"
                     /protein_id="HCR9913019.1"
                     /translation="MIIATAGHVDHGKTTLLQAITGINADRLPEEKKRGMTIDLGYAY
                     WPQPDGRVLGFIDVPGHEKFLSNMLAGVGGIDHALLVVACDDGVMAQTREHLQILQLT
                     GNLQLTVALTKADRVDEARISEVREEVLAALDNYGFADTVLFVTAANEGRGIAELRAH
                     LQQLPARLHAAQHRFRLAIDRAFTVKGAGLVVTGTALSGEVNVGDTLWLTGVNTPMRV
                     RSLHAQNQPTDHAYAGQRIALNIAGDAEKEQLNRGDWLLSDAPAGEAFSRVIVSLALH
                     APLSQWQPLHIHHAASHVTGRVSLLEGALAELIFDTPLWLADNDRLVLRDISARATLA
                     GARVVTLNAPRRGKRKPDYLHWLSTLADAQDDSAALAIHLERGAVNLPDFGWARQLNP
                     LGMRQLIEQHGFIQAGDNLLSAPVAARWQRKILDTLATYHEQHRDEPGPGRERLRRMA
                     LPMEDEALVLMLIERMRDEGLIHSHHGWLHLPDHKAGFSDEQQAVWQKVEPLFGDEPW
                     WVRDLAKETGTEEQLMRLVLRQAAQQGIITAIVKDRYYRNDRIVAFANMIRELDQERG
                     STCAADFRDRLNVGRKLAIQILEYFDRIGFTRRRGNDHLLRDALLFPQKE"
     gene            complement(9523..10404)
                     /locus_tag="OPV72_000644"
     CDS             complement(9523..10404)
                     /locus_tag="OPV72_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCR9913020.1"
                     /translation="MQQYIGIDVGGTHVKYGVINSDGEELTHHQFDTPEDASTFTRKW
                     QDVVARCQQDYDIAAIGVSFPGHINPHNGHAAKAGALAYLDDVNLMELFSGLTDLPLV
                     VENDANCAALGEMWRGAGQHYDNLVCITIGTGIGGGIIVGRELYRGAHFHAGEFGVMP
                     VGNNGESMHKIASTSGLMASCRQALALPAEEMPPADVIFERMATDVHLREAVNDWARY
                     LSRGVYSVISMFDPGVVLIGGGISEQEKLYPLLTRHLETFEMWEALQVPIQPCQLGNQ
                     AGRLGAVWLAQQKLDRR"
     gene            10573..12111
                     /gene="aldB"
                     /locus_tag="OPV72_000645"
     CDS             10573..12111
                     /gene="aldB"
                     /locus_tag="OPV72_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase AldB"
                     /protein_id="HCR9913021.1"
                     /translation="MTNNPPSTRIQPSEYGYPLKLKARYDNFIGGDWVAPADGEYYQN
                     LTPVTGQPLCEVASSGKKDIDLALDAAHKAKDKWAHTSVQDRAAILFKIADRMEQNLE
                     LLATAETWDNGKPIRETSAADIPLAIDHFRYFASCIRAQEGGISEVDSETVAYHFHEP
                     LGVVGQIIPWNFPLLMASWKMAPALAAGNCVVLKPARLTPLSVLLLMEVIGDLLPPGV
                     VNVVNGAGGEIGEYLATSKRIAKVAFTGSTEVGQQIMQYATQNIIPVTLELGGKSPNI
                     FFADVMDEEDAFFDKALEGFALFAFNQGEVCTCPSRALVQESIYERFMERAIRRVESI
                     RSGNPLDSGTQMGAQVSHGQLETILNYIDIGKKEGADILTGGRRKELDGELKEGYYLE
                     PTILFGKNNMRVFQEEIFGPVLAVTTFKTMEKALEIANDTQYGLGAGVWSRNGNLAYK
                     MGRGIQAGRVWTNCYHAYPAHAAFGGYKQSGIGRETHKMMLEHYQQTKCLLVSYSDKP
                     LGLF"
     gene            complement(12229..14184)
                     /locus_tag="OPV72_000646"
     CDS             complement(12229..14184)
                     /locus_tag="OPV72_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 127 protein"
                     /protein_id="HCR9913022.1"
                     /translation="MNVLEVDLHKLTVSDPLLGQYQQLVRDVVIPYQWDALNDRIPEA
                     EPSHAIENFRIAAGQQTGDFYGMVFQDSDVAKWLEAVAWSLCQKPDPELEKTADEVIE
                     LVAAAQCDDGYLNTYFTAKAPQERWSNLAECHELYCAGHLIEAGVAFFQATGKRRLLD
                     VVCRLADHIDSTFGPGENQLHGYPGHPEIELALMRLYEVTEQPRYMTLASYFIGQRGA
                     QPHFYDEEYEKRGQTSYWHTYGPAWMVKDKAYSQAHLPISQQQTAIGHAVRFVYLMTG
                     VAHLARLSNDEGKRQDCLRLWKNMAQRQLYITGGIGSQSSGEAFSSDYDLPNDSVYAE
                     SCASIGLMMFARRMLEMEADSQYADVMERALYNTVLGGMALDGKHFFYVNPLEVHPKS
                     LKFNHIYDHVKPIRQRWFGCACCPPNIARVLTSIGHYIYTPRADALYINMYVGNSMEI
                     PVENGALKLRISGNYPWHEQVKIAIDSVQPVRHTLALRLPDWCPEAKVTLNGLEVEQD
                     IRKGYLHIRRTWQEGDTISLTLPMPVRRVYGNPLARHVAGKVAIQRGPLVYCLEQADN
                     GEELHNLWLPKESEFRVFEGKGLFAHKMLIQAEGEKQSAADAQHQALWHYDNAPSSRQ
                     PQTLTFIPWFSWANRGEGEMRIWINER"
     gene            14448..15260
                     /locus_tag="OPV72_000647"
     CDS             14448..15260
                     /locus_tag="OPV72_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCR9913023.1"
                     /translation="MLELSITLPIKVQNGGLFISRGIGRHPARRLQSWEIIFVEKGCL
                     KIQEECVFCVEAGESLLLWPHRRHIGVEEFPADLKFYWLHFEVKAPDSDPRWLTHLSV
                     PQHTQVADPQALIALFRQFMNEQEKHQRSPALEFIVLLILQQLTVDARQNENAEAAGV
                     SLAWKAQQLIRTHYHLPLSSAVLAKELHCNVDYLGRVYRRVFHLTLTEAIHRQRVREA
                     EKLLISDARSLKEVAERCGFNDVGYFRQIFRKHTGLTPTAWKRRYSKEHVNS"
     gene            complement(15421..16116)
                     /gene="araD"
                     /locus_tag="OPV72_000648"
     CDS             complement(15421..16116)
                     /gene="araD"
                     /locus_tag="OPV72_000648"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HCR9913024.1"
                     /translation="MLEQLKAEVLAANLALPAHGLVTFTWGNVSAVDETRKLMVIKPS
                     GVEYEVMTADDMVVVEIASGKVVEGNKKPSSDTATHLALYRRYPQIGGIVHTHSRHAT
                     IWSQAGLDLPAWGTTHADYFYGAIPCTRLMTVEEINGEYEYQTGEVIIKTFEERGLDP
                     AQIPAVLVHSHGPFAWGKNAADAVHNAVVLEECAYMGLFSRQLAPQLPDMQPELLDKH
                     YLRKHGANAYYGQ"
     gene            complement(16110..16970)
                     /locus_tag="OPV72_000649"
     CDS             complement(16110..16970)
                     /locus_tag="OPV72_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HCR9913025.1"
                     /translation="MRNHPLGIYEKALAKDLSWPERLVLAKSCGFDFVEMSVDETDER
                     LSRLEWTSAQRASLVNAMLESGVAIPSMCLSAHRRFPFGSRDEAVRQRAREIMTKAIR
                     LARDLGIRTIQLAGYDVYYEEHDEGTQQRFAEGLAWAVEQAAAAQVMLAVEIMDTAFM
                     NSISKWKKWDEMLSSPWFTVYPDVGNLSAWGNDVTAELKLGIDRIAAIHLKDTLPVTG
                     DNPGQFRDVPFGEGCVDFVSIFKTLHELNYRGSFLIEMWTEKASEPVLEIIQARRWIE
                     SRMQEGGFTC"
     gene            complement(16963..17625)
                     /gene="ulaD"
                     /locus_tag="OPV72_000650"
     CDS             complement(16963..17625)
                     /gene="ulaD"
                     /locus_tag="OPV72_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HCR9913026.1"
                     /translation="MSRPLLQLALDHTSLEAAQRDVALLQDHVDIVEAGTILCLTEGL
                     SAVKALRAQCPEKIIVADWKVADAGETLAQQAFSAGANWMTIICAAPLATVEKGHAVA
                     QSCGGEIQMELFGNWTLDDARDWYRVGVRQAIYHRGHDAQASGQQWGEADLARMKALS
                     DIGLELSITGGITPADLPLFRDINVKAFIAGRALAGAAHPAQVAAEFHAQIDAIWGEK
                     HA"
     gene            complement(17622..19118)
                     /locus_tag="OPV72_000651"
     CDS             complement(17622..19118)
                     /locus_tag="OPV72_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase"
                     /protein_id="HCR9913027.1"
                     /translation="MSNYWLGLDCGGSWLKAGLYDGAGREVAVQRLPLHALSPQPGWV
                     ERDMTELWQQCASVISKLLTHTGVSGSQIRGLGISAQGKGLFLLDKSDRPLGKAILSS
                     DRRAMEIVQRWQKEAVPQKLYPLTRQTLWTGHPVSLLRWVKENEPQRYAQIGSVMMTH
                     DYLRWCLTGVKGCEESNISESNLYNMATGQYDPRLTEWLGISEIDSALPPVVGSAEIC
                     GEITAQAAAITGLAAGTPVVGGLFDVVSTALCAGIEDESTLNAVMGTWAVTSGIAHGL
                     RDHEAHPYVYGRYVNDGQYIVHEASPTSSGNLEWFTAQWGYLSFDEINQAVASLPKAG
                     SDLFFLPFLYGSNAGLEMTCGFYGMQALHNRAHLLQALYEGVVFSHMTHLNRMRERFT
                     EVCALRVTGGPAHSDVWMQMLSDVSGLRIELPQVEETGCFGAALAARVGTGVYRDFHE
                     AQRDLQHPVRTLLPDMTAHALYQRKYRQYQDLIEALQGYHARIKEHAL"
     gene            complement(19122..20108)
                     /locus_tag="OPV72_000652"
     CDS             complement(19122..20108)
                     /locus_tag="OPV72_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HCR9913028.1"
                     /translation="MKLHVIARSLLIAGLTVFSVSSLAAQSLRFGYETPQTDSQHIAA
                     KKFNELLKEKTNGELTLKLFPDSTLGNAQAMISGVRGGTIDMEMSGSNNFTGLAPVFN
                     LLDVPFLFRDTSHAHKTLDGKVGDELKKSLDSKGLKVLAYWENGWRDVTNSRAPVKTP
                     GDLKGLKIRTNNSPMNIAAFKIFGANPIPMPFSEVYTGLETRTIDAQEHPINVVWSAK
                     FYEVQKYLSLTHHAYSPLLLVINKAKFDALSPQFQEALLSSAKEAGDYQRKLVAEDQQ
                     KIIDGMKEAGVEVLTDIDRKAFSDALGSQVRDMFLKDNPQGADLLKAVDEVQ"
     gene            complement(20120..21397)
                     /gene="yiaN"
                     /locus_tag="OPV72_000653"
     CDS             complement(20120..21397)
                     /gene="yiaN"
                     /locus_tag="OPV72_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diketo-L-gulonate transporter large permease
                     YiaN"
                     /protein_id="HCR9913029.1"
                     /translation="MAVVIFLCCLLGGIAIGLPIAWSLLLCGAALMAYLDMFDVQIMA
                     QTLVNGADSFSLLAIPFFVLAGEIMNAGGLSKRIVDLPMKLVGHKPGGLGYVGVIAAM
                     IMASLSGSAVADTAAVAALLVPMMRSANYPINRSVGLIASGGIIAPIIPPSIPFIIFG
                     VSSGLSISKLFMAGIAPGIMMGAALMLTWWWQAGRLNLPSQPKATPREIWYSLVSGIW
                     ALFLPVIIIGGFRSGLFTPTEAGAVAAFYALFVAVVIYRELTFSSLYHVLVNAAKTTS
                     VVMFLVAAAQVSAWLITIAELPMIVSDLLQPLVDSPRLLFIVIMISIMVVGMVMDLTP
                     TVLILTPVLLPLVKEANIDPIYFGVMFIINCSIGLITPPVGNVLNVISGVAKLKFDDA
                     VRGVFPYVVVLMSLLVLFIFIPELIITPLKWIN"
     gene            complement(21400..21873)
                     /gene="yiaM"
                     /locus_tag="OPV72_000654"
     CDS             complement(21400..21873)
                     /gene="yiaM"
                     /locus_tag="OPV72_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diketo-L-gulonate TRAP transporter small
                     permease YiaM"
                     /protein_id="HCR9913030.1"
                     /translation="MKRVLEGILAVLIAVLSCIVFINVILRYGFESSILSVDELSRYL
                     FVWLTFIGAIVAFMDNAHVQVTFVVEKLSPANQRRLSLLTHSLILLLCIALGWGSLQK
                     ALQDWSDHSPILGLPIGLMYIACLPTSVAIALIELRRLYHLITRNDSFQQPQQGA"
     gene            complement(22012..22944)
                     /locus_tag="OPV72_000655"
     CDS             complement(22012..22944)
                     /locus_tag="OPV72_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4862 family protein"
                     /protein_id="HCR9913031.1"
                     /translation="MKNNTGYIIGAYPCAPSFHQKSEEEETEFWRQLSDTPDIRGLEQ
                     PCLEHLHPLGDEWLLRHTPGNWQIVVTAIMETMRRRSENGGFGLASSDEEQRKACVEY
                     YRHLHQKINKINGNNTGKVIALELHAAPLAGNPNVAQATDAFARSLKEIANWDWSCDL
                     VLEHCDAMTGPAPRKGFLPLVNVLETIADYDISVCINWARSAIEGRDTSLPLIHTQQA
                     KQAGKLGALMFSGTTLDGEYGEWQDLHAPFAPFCPQSLMTEKHVKELITAAAPELLQF
                     TGIKLLEINASADINHRINILRDGINMMKKATRR"
     gene            complement(22968..23432)
                     /locus_tag="OPV72_000656"
     CDS             complement(22968..23432)
                     /locus_tag="OPV72_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HCR9913032.1"
                     /translation="MIFGHIAQPNPCHLPAAIEKALHFLRTTDFRTLEPGVVEIDGKN
                     TFAQIIDMTTRDAAENRPEVHRRYLDIQFLAWGEEKIGVAIDTGNNQISESLLEQRDI
                     IFYHDSEHESFIEMIPGSYALFFPQDVHRPGCNKSIATPIRKIVVKVAIDVL"
     gene            complement(23444..24442)
                     /gene="yiaK"
                     /locus_tag="OPV72_000657"
     CDS             complement(23444..24442)
                     /gene="yiaK"
                     /locus_tag="OPV72_000657"
                     /EC_number="1.1.1.130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydro-L-gulonate 2-dehydrogenase"
                     /protein_id="HCR9913033.1"
                     /translation="MKVTFEELKGAFYRVLRSRNIAEDTADACAEMFARTTESGVYSH
                     GVNRFPRFIQQLDNGDIIPDAKPQRVTSLGAIEQWDAQRAIGNLTAKKMMDRAIELAS
                     DHGIGLVALRNANHWMRGGSYGWQAAEKGYIGICWTNSIAVMPPWGAKECRIGTNPLI
                     VAIPSTPITMVDMSMSMFSYGMLEVNRLAGRELPVDGGFDDNGQLTKEPGVIEKNHRI
                     LPMGYWKGSGLSIVLDMIATLLSNGSSVAEVTQENSDEYGVSQIFIAIEVDKLIDGAT
                     RDAKLQRIMDFITTAERADDNVAIRLPGHEFTKLLDDSRCNGITIDDSVWAKIQAL"
     gene            24672..25472
                     /gene="yiaJ"
                     /locus_tag="OPV72_000658"
     CDS             24672..25472
                     /gene="yiaJ"
                     /locus_tag="OPV72_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator YiaJ"
                     /protein_id="HCR9913034.1"
                     /translation="MSQNNDKEKPAGSQSLFRGLMLIEILSNYPNGCPLAHLSELAGL
                     NKSTVHRLLQGLQSCGYVTPAPAAGSYRLTTKFIAVGQKALSSLNIIHVAAPHLEALN
                     LATGETVNFSSREDDHAILIYKLEPTTGMLRTRAYIGQHMPLYCSAMGKIYMAFGQPD
                     YVASYWESHKDQIQPLTRNTITDLPAMYDELAQIRETSMAMDREENELGVSCIAVPVF
                     DIHHRVPYAISISLSTSRLKQIGEKNLLKPLRETAQAISNELGFTVRE"
     gene            25589..26062
                     /locus_tag="OPV72_000659"
     CDS             25589..26062
                     /locus_tag="OPV72_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HCR9913035.1"
                     /translation="MNRFIMADASACIGCRTCEVACVVSHQEQQNSAAVTTADFVPRI
                     RVIKEDSFTTATVCHQCEDAPCANVCPVQAIRRDRGHIFVTPSRCIGCKSCMLACPFG
                     AMTVVASASGAQAIKCDLCWHREAGPACVEACPTSALQCVDATHVQRQRLYSQPF"
     gene            complement(26099..27349)
                     /gene="avtA"
                     /locus_tag="OPV72_000660"
     CDS             complement(26099..27349)
                     /gene="avtA"
                     /locus_tag="OPV72_000660"
                     /EC_number="2.6.1.66"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--pyruvate transaminase"
                     /protein_id="HCR9913036.1"
                     /translation="MTFSLFGDKFTRHSGITRLMEDLNDGLRTPGAIMLGGGNPAHIP
                     AMQDYFQTLLTEMVESGKAADALCNYDGPQGKTALLNALAVLLRETLGWDIEPQNIAL
                     TNGSQSAFFYLFNLFAGRRADGSTKKVLFPLAPEYIGYADSGLEDDLFVSARPNIELL
                     PEGQFKYHVDFEHLHIGEETGMICVSRPTNPTGNVITDEELMKLDRLANQHNIPLVID
                     NAYGVPFPGIIFSEARPLWNPNIILCMSLSKLGLPGSRCGIIIANDKTITAIANMNGI
                     ISLAPGGMGPAMMCEMIKRNDLLRLSETVIKPFYYQRVQQTIAIIRRYLSEERCLIHK
                     PEGAIFLWLWFKDLPITTELLYQRLKARGVLMVPGHYFFPGLDKPWPHTHQCMRMNYV
                     PEPDKIEAGVKILAEEIERAWREG"
     gene            complement(27523..29550)
                     /locus_tag="OPV72_000661"
     CDS             complement(27523..29550)
                     /locus_tag="OPV72_000661"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HCR9913037.1"
                     /translation="MKLAAFALTLIPGIAIASSWTSPGFPTLSTQETGRFTSHAALTK
                     GTRALTLHIDQQCWQPSGAIKLNQMLSLKPCEGAPPQWRLFKDGDYTITVDTRSGTPT
                     LLLSIKTEPERTTQLAYQCPVWDGSPLTLDVRQTFPEGTVVRDYYSGQIDTVQNGKIT
                     LLPADSHGLLLLERAETHASAPFNWRNATVYFVLTDRFRNGDPTNDHSYGRHKDGMQE
                     IGTFHGGDLRGLTSQLDYLQQLGVNALWISSPFEQIHGWVGGGTKGDFPHYAYHGYYT
                     QDWTTLDANMGSEADLRALVDGAHQRGIRILFDVVMNHAGYATLADMQEYQFGALYLS
                     GAERQKILGDRWTNWRPAAGQSWHSFNDYINFSDSAAWEKWWGKKWIRTDIGDYDSPG
                     FDDLTLSLAFLPDIKTESTTPSGLPVFYANKPDTKAKFIEGYTPRDYLTHWLSQWVHD
                     YGIDGFRIDTAKNVELPAWQQLKTQASAALHEWKQANPDKALDDSPFWMTGEAWGHGV
                     MKSDYYRYGFDAMINFDYQEQAAKAVDCLAEMGPVWQQMADKMQDFNVLSYLSSHDTR
                     LFREGGDKAAELLLLSPGAVQIFYGDESARPFGPTGSDPLQGTRSDMNWQDVSGKSAA
                     AVAHWQRISQFRARHPAIGAGQQTTLTLKHGYGFVRQYGDDTVMVVWAGRR"
     gene            29866..30690
                     /locus_tag="OPV72_000662"
     CDS             29866..30690
                     /locus_tag="OPV72_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein bax"
                     /protein_id="HCR9913038.1"
                     /translation="MILTPMRRYGAMILMLLTIAFSGEVLAKTRATQTSQKSHITETS
                     YKQVSSKQEYSRNSAKSSSLPDLRKYPSGTPRKKAFLRTVMPYITSQNAAITADRNWL
                     ISKQYQNRWSPSERARMKDIAKRYKVSWSGNTRRIPWNTLLERVDIIPTSMVATMAAA
                     ESGWGTSKLARSNNNLFGMKCTKGRCTNTPGKVKGYSQFASVEESVSAYVANLNTHPA
                     YSSFRKSRAQLRKADQEVTATAMIHKLKGYSTQGARYNNYLFAMYQDNQRLIAAHM"
     gene            complement(30751..31929)
                     /locus_tag="OPV72_000663"
     CDS             complement(30751..31929)
                     /locus_tag="OPV72_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XylR family transcriptional regulator"
                     /protein_id="HCR9913039.1"
                     /translation="MFDKRHRITLLFNANKAYDRQVVEGVGEYLQASQSEWDIFIEED
                     FRARIDNIKEWLGDGVIADYDDDDIAQLLADVDVPIVGVGGSYHLAENYPAVHYIATD
                     NHALVESAFLHLKEKGVNRFAFYGLPDSSRKHWAAEREYAFRQLVAEEKYRGVVYQGL
                     ETAPENWQHAQNRLADWLQTLPPQTGIIAVTDARARHVLQACEHLHIPVPEKLCVIGI
                     DNEELTRYLSRVALSSVAQGARQMGYQAAKLLHRLLAREEMPLQRILVPPVRVIARRS
                     TDYRSLTDPAVIQAMHFIRNHACKGIKVEQVLDAVGISRSNLEKRFKEEVGETIHALI
                     HAEKLEKARSLLISTTLAINEISQMCGYPSLQYFYSVFKKEYVTTPKEYRDQHSEALL
                     "
     gene            32292..33614
                     /gene="xylA"
                     /locus_tag="OPV72_000664"
     CDS             32292..33614
                     /gene="xylA"
                     /locus_tag="OPV72_000664"
                     /EC_number="5.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase"
                     /protein_id="HCR9913040.1"
                     /translation="MQAYFDQLDRVRYEGPQSTNPLAFRHYNPDELVLGKRMEDHLRF
                     AACYWHTFCWNGADMFGVGAFNRPWQQPGEALELAKRKADVAFEFFHKLNVPFYCFHD
                     VDVSPKGASLKEYKNNFAQMVDVLAAKQEQSGVKLLWGTANCFTNPRYGAGAATNPDP
                     EVFSCAATQVVTAMNATHKLGGENYVLWGGREGYETLLNTDLRQEREQIGRFMQMVVE
                     HKHKMGFQGTLLIEPKPQEPTKHQYDYDVATVYGFLKQFGLEKEIKVNIEANHATLAG
                     HSFHHEIATAIALGIFGSVDANRGDAQLGWDTDQFPISVEENALVMYEILKAGGFTTG
                     GLNFDAKVRRQSTDKYDLFYGHIGAMDTMALSLKIAARMVEDGELDKRVAKRYAGWNG
                     ELGQQILKGQLSLGELAQYAEQHHLAPVHQSGHQELLENLVNRYLFDK"
     gene            33714..35168
                     /gene="xylB"
                     /locus_tag="OPV72_000665"
     CDS             33714..35168
                     /gene="xylB"
                     /locus_tag="OPV72_000665"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HCR9913041.1"
                     /translation="MYIGIDLGTSGVKAILLNEQGDVLATHTEKLTVSRPHPLWSEQE
                     PEQWWQATDRAVKGLGRQQSLSGVRALGIAGQMHGATLLDSRQQVLRPAILWNDGRCS
                     EECAWLEKQVPQSRAITGNLMMPGFTAPKLVWVQRHEPDIFYQIDKVLLPKDFLRLRM
                     TGVFASDMSDAAGTMWLDVKKRDWSDVMLNACHLTRQQMPALFEGSDITGTLLPEVAS
                     AWGMPAVPVVAGGGDNAAGAVGVGMIDAGQAMLSLGTSGVYFAVSDGFLSKPESAVHS
                     FCHALPERWHLMSVMLSAASCLDWAAKLTGQENVPALIAAAQQADEHADSIWFLPYLS
                     GERTPHNNPQAKGVFFGLTHQHGPAELARAVLEGVGYALADGMDVVHACGVKPASVTL
                     IGGGARSEYWRQMLSDISGLQLDYRTGGDVGPALGAARLAQIAVNKQTPLADVLPQLP
                     LEQAHYPDAQRHAVYQQRRETFRRLYQQLLPLMS"
     gene            35343..35696
                     /locus_tag="OPV72_000666"
     CDS             35343..35696
                     /locus_tag="OPV72_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiaA/YiaB family protein"
                     /protein_id="HCR9913042.1"
                     /translation="MDDHVARRKRIFGLGMLVVGAVVYLVGLWPGCHTLSEKGYFFAA
                     IVMCGFPVLIRQEHTGNDRLLSRCKSLLLLGIGMVAVGVFNLALAGALKILCLVALGV
                     SIYGTDLYASYSDDE"
     gene            complement(35719..36713)
                     /locus_tag="OPV72_000667"
                     /pseudo
     CDS             complement(35719..36713)
                     /locus_tag="OPV72_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462558.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
     gene            36879..37181
                     /locus_tag="OPV72_000668"
     CDS             36879..37181
                     /locus_tag="OPV72_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCR9913043.1"
                     /translation="MIMKYFCTVMIAIALVGCTATPPPTQKAQQSKVSPTRTLDMEAL
                     CKAQAAQRYNTGAQKIAVTGFEQFQGSYEMRGNTFRKESFVCSFDADGQFLHLSMR"
     gene            37320..38231
                     /gene="glyQ"
                     /locus_tag="OPV72_000669"
     CDS             37320..38231
                     /gene="glyQ"
                     /locus_tag="OPV72_000669"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HCR9913044.1"
                     /translation="MQKFDTRTFQGLILTLQDYWARQGCTIVQPLDMEVGAGTSHPMT
                     CLRALGPEPMATAYVQPSRRPTDGRYGENPNRLQHYYQFQVVIKPSPENIQELYLGSL
                     KELGMDPTIHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECKLVT
                     GEITYGLERLAMYIQGVDSVYDLVWSDGPLGKTTYGDVFHQNEVEQSTYNFEYADVDF
                     LFTCFEQYEKEAQQLLALENPLPLPAYERILKAAHSFNLLDARKAISVTERQRYILRI
                     RTLTKAVAEAYYASREALGFPMCNKDK"
     gene            38241..40310
                     /gene="glyS"
                     /locus_tag="OPV72_000670"
     CDS             38241..40310
                     /gene="glyS"
                     /locus_tag="OPV72_000670"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HCR9913045.1"
                     /translation="MSEKTFLVEIGTEELPPKALRSLAESFAANFTAELDNAGLAHGT
                     VQWFAAPRRLALKVANLAEAQPDREIEKRGPAIAQAFDAEGKPSKAAEGWARGCGITV
                     DQAERLTTDKGEWLLYRAYVKGESTEALLPNMVATSLAKLPIPKLMRWGASDVHFVRP
                     VHTVTLLLGDKVIPATILGIQSDRVIRGHRFMGEPEFTIDNADQYPEILRERGKVIAD
                     YEERKAKIKADAEEAARKIGGNADLSESLLEEVASLVEWPVVLTAKFEEKFLAVPSEA
                     LVYTMKGDQKYFPVYANDGKLLPNFIFVANIESKDPQQIISGNEKVVRPRLADAEFFF
                     NTDRKKRLEDNLPRLQTVLFQQQLGTLRDKTDRIQALAGWIAEQIGADVNHATRAGLL
                     SKCDLMTNMVFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDDLPSNPVAC
                     ALAIADKMDTLAGIFGIGQHPKGDKDPFALRRAALGVLRIIVEKNLNLDLQTLTEEAV
                     RLYGDKLTNASVVDDVIDFMLGRFRAWYQDEGYSVDTIQAVLARRPTRPADFDARMKA
                     VSHFRTLEEASALAAANKRVSNILAKATEPLNDIVHASVLKEAAEIELARHLVVLRDK
                     LQPYFADGRYQEALIELAALRAPVDEFFENVMVNAEEKDIRINRLTLLSKLRELFLQV
                     ADISLLQ"
BASE COUNT         9289 a        10604 c        11043 g         9402 t
ORIGIN      
        1 aattcggaat atagcccgat gcattcaaga caccctccgt acaacgggtg tcttgagagc
       61 ctgggatgcg gaaggtttag aactcgctct tcgcgaaacc tgtcatctct ttgagtccca
      121 tttcccggcc cagcgccgtc atcgggtgca ctacgatcag accacgcacg cttttcttca
      181 acttgcccat atcggcctgc tcttttttag tgatagcgcg gcgaaacggc aggttcatca
      241 gcttctgcgc ttctttactc agtttctggc tgtgtacttc gcgcagacgg ataatttctg
      301 cttccagcgt ctctttttct ttttccagct ccgcgtattt atcggcggat tcaaccagcg
      361 agagacctgc ctgctggtgg cgaatagcgt caagacgatc gctcaggcgt ttaatttcgt
      421 ttttttcgac ttctttcatg ggatagcttc tgatagaaat gggatagata ccctatagta
      481 tgcgcgcagt gggtgattct tcacaactca tggcgtaacg ataatcaatt atggtaaata
      541 ttacaccgct aattatttat ttatccattt gaaaataaag tgcttttttt cgaaagaaaa
      601 gatgaaacgc ctttttgtcg gcaagaaaag caattaagca cattttcctc aatgatgacg
      661 ctaaatcgat cctaaactca aataagcggc cgcgggagtc agacgcggat cacacatgga
      721 ggatctatca tggcaaaaat aggtgagaac gtaccacttc ttattgataa agccgtcgat
      781 tttatggcgt ccagccaggc gttccgtgag tacttgaata aaacgccgcc gcgtgattat
      841 gttccttccg aagtgccgtc ggagagcacg cccatttatt tgcagcgtct ggaatattac
      901 cggcggctgt accgaccaaa agaagaaaga ggttaacggc gggatttact tttgaaaggc
      961 cttttttaag ctgattttag aaatcagctc ggtcagagag agaaccatcg tcgaacgcac
     1021 cgcctgctgg tagcgctgaa tttgcatggc gtatagcgcc gcgtcggatg tatcaaaatg
     1081 tggcggcggc ggcagcgcca tgacgcaatg cagttcgcca aacggcccga ggatttcatc
     1141 gtcggtaaag gcgtactcat tgccgtcgtg attcagctct tcgcgcagcg ccattaacag
     1201 ctccgcatct tcatattcgg tgcggctgag tacgcccagg ccatagataa gtttcagacg
     1261 taccgaaaga tcgcccagcg gcccgtcgcc gtccagcaac ggttccacag cgtatttcac
     1321 ggcatagtcg tctttgcgaa acacctgaag caccagaata ttcaccgcct cggtcagtaa
     1381 ctcgacggcg gtaatcagga agctccgtac ggttttgcca gcattcagac gctcaagcac
     1441 acgattttca aaggcctggg tttgttccat tattgcctgc atatctgaca atctgttatt
     1501 tgggcgcagg ctaacctgcg ccgggttctg cgtcatttgg tcgcgttata tgcgttaacc
     1561 gcctccgcca ccacatcgct attggcatcc agcccggaaa tttgcgccag cgcggcctgc
     1621 gggccttttt cggtaatcag cgccgccaac tcttgtgcct gcggatcttc atcgctacgg
     1681 aaatgcatcg ccgccgcgat ccctttcacc agattcacat gcggcagacc atattccagg
     1741 gtgccaagca gcggtttgat cagacggtcg cccgcgctga gtttgcgtag cggctgacgg
     1801 cctacgcgtt cgacgtcatc tttcagatac gggttttcaa aacgaccgag gattttctga
     1861 atgtatgccg catgtttgtc ggcatcaaaa ccgtagcgtt tgatcagcac cgcgccgctt
     1921 tcttccatcg cgcctttcac caccgcgcga ataccctcat cgagaatggc gtcgcgaatg
     1981 gtttgatgac cggctaattt gccgaggtac gcggttatag catgacctgt gttcagcgtg
     2041 aagagtttac gttcgacaaa tgccatcagg ttatccgtta actccatccc cggaatgttt
     2101 ggcaacgcgc ctttaaactg ggttttatcg acgatccact cgctgaaggt ttctaccgtc
     2161 acttccagcg gatcgttggt cgcagaagca gatggcggca caatacggtc aacggcggaa
     2221 tcgacaaaac cgacgtgctg ttcaacccag gctttatcgc catccgccag cgcgttcatt
     2281 acgtggcctt tcagctgcgt ggtgccgcgc accatatttt cgcaggcgat gatattcagc
     2341 ggggcatcca cgccctgcgc cttacgtttt accagccctt tagcgatagc cggtgcgata
     2401 cgctcaagca ccaccgggcc cacggcagtg gtgattaaat caacgtgggc aatcaggtcg
     2461 acaacatcat cgccgatgct gctgacagcg ttgacgccgg aaacggtatc cacctgctca
     2521 ttttcaccca caacatgaac ctgatagcta tgacgggcat tcagggcatc gagtacgacc
     2581 tggtttacat ccgcaaacgt cagttgtatc cccgcgtcag ccagcaattt gccgataaag
     2641 ccacgaccga tattacctgc gccaaaatgt aatgctttca tagtattaac cttcattaat
     2701 gtttttaccc gagagggctg gggtgaggct tttccctcaa cctaaccctc tccacaagag
     2761 agaggatatc gccttcatat ttagaactgc agatgcgttg gctctcctcg ctcaccccag
     2821 tcacgtactt atgtacgctc ctggggattc actgcgttgc cgccttcctg cagctcgaac
     2881 tattttgggg atacttaact gttaagcttt tttacctgcc agcagttcca gcacttcatc
     2941 cacgctggtg gtgtgcgcca gacgttcgat cacggattca tcatccagcg cgttggtcaa
     3001 gctggtgatg acctggatgt gctcattgtt acgtgcggcg ataccaatga ccagacgggc
     3061 aatatcgtct tcttcttcac cgaagcgtac gccttccgga tactggcaga acaccacgcc
     3121 ggttttcagc acgcggtctt tagcttctac ggtaccgtgc ggtaccgcga tggattcacc
     3181 gaggtaagtc ggcgtcagct tttcgcggtc cagcatcgcc tcgacgtatt ccggctcaac
     3241 atagccgcct ttcaccagtt gttcaccggc aaagcgaatc gcctcttctt tgttagcggc
     3301 tttacggccc aggaagatat tctccgcgcc cagcttgaac aggttgttat cgccctcttc
     3361 aaagctatct ttcagatgat cgcggacttt ctcttcatta gtattgtggc gctgtgcggc
     3421 aaccagacgt tcggtcaggc tggtgtacag gccgctatcc aggaagttgg tcagcgaaat
     3481 atgctgcgcc tgcggtacct gacgcatagc acgttcggtc aggtcgcggt gagtaatgac
     3541 cagatccaca tccggcggca gattgttaat ggcgctgttg gtgacggaaa tctgagacag
     3601 acccgcatcc tgtactttct tacgcagtac ccctgcgccc atcgcgctgg aacccatacc
     3661 ggcatcgcaa gctacgatga ttttacgcac atggctgagg tcattggtga cgtcgccagc
     3721 cgccagcgga gaggcgcctt tagattccgc tttcatgtca tgcatacgac gggtggccgc
     3781 ttcaatatca tcttcttctt tcactttgct ggttttcagc agaattgcag acaccacgaa
     3841 ggagaccgcc attgccgcca cgatggccgc gatgttagcg aagtaagcgc cttttggcgt
     3901 catcgccagt accgccagaa tggagcctgg agacgccgga gagaccagac cgccgttcag
     3961 gatggtcagg gtgaatacgc cggtcatacc gccgagaatc accgccagaa tcaggcgtgg
     4021 gttcatcagc acgtacggga agtaaatttc gtggataccg cctaggaagt ggataattgc
     4081 cgcgccgccc gcagactgtt tagcgctgcc gcgaccgaag aacatgtacg ccagcaggac
     4141 gcccatcccc ggacccgggt tagcttcaat caggaagaag atggatttac ccatctcatg
     4201 ggactgctgg atacccagcg gtgagaagat gccgtggtta atcgcgttat tgaggaacag
     4261 gattttcgcc ggttcaacaa aaatggacgc cagcggcagc atatcgtgcg ccaccatgaa
     4321 gttaacgccc gccgccagaa ttttggacag gacttcaacc gccggaccaa taccgaggaa
     4381 cgccaggatg gcgaggatca taccgatgat gccagcggag aagttgttca ccagcatctc
     4441 aaaaccggat ttgatcttac cgtctaccca actgtcgaat ttcttaatgc agtagccgcc
     4501 taatggaccg gcgatcatcg agccgaggaa catcggcata tccgcgccga caataacgcc
     4561 catggtagta atagcgccta ccacgccgcc gcgttcgccg ccaaccagac gaccgccggt
     4621 ataaccgatg agcagcggca gcaggtaggt gatcatcgga ccaaccagtt tcgccagcgt
     4681 ttcgttaggc aaccaccctg ttggaataaa taatgcggtg ataatacccc acgcgataaa
     4741 cgcgccgata ttaggcatca ccatattgct gaggaatcga ccaaagcttt gcactttgat
     4801 cttaatatcg gatgacataa aaacacccct tcttatgttg ctgtcgcgca ggctgaaagc
     4861 ccgaggtttg ttaatgtagc ggcagaggta gccggaccct gtagtgtaga tactgcgcaa
     4921 tctggcactg aatcgttcaa ctgtccagac aaggataatt tatgtgattt gcgtcacata
     4981 aatatagggg tagagaggta atttatgtga tattgatcac aaagttactg tgtaaaaaaa
     5041 caacgaatct catttttagc ccttaaaagg ctattttatg tgagatattt cacactttta
     5101 ttttggtgct ttgttgaatt tttgtgatcc tcttcacatg aaattttaag cccgggtaac
     5161 gtcaatacga tccgacaaac attttgtcgc gagccctctc acgttatgtc attcagcaac
     5221 ttccttttgt gtctcttttc gtcttatttg agccatacta tgatttttac tggttggcaa
     5281 aaaggacacg gcatgaaact catcggtagc tacaccagcc cttttgtgcg caaaatctct
     5341 gttctgctgc tcgaaaaggg tattaccttc gaatttatta atgaactacc ttacgaggcg
     5401 gataacggcg tggcgcaata caaccctctg ggtaaggtgc cagcgctggt gacggagaaa
     5461 ggggagtact ggttcgattc gccgatcatc gcggaatata ttgaactgct ggatatcgcg
     5521 ccagcgatgc tcccgcgtga cccgatggca gcgcttaaag ttcgccagct tgaagcgttg
     5581 gctgacggca ttatggatgc agcgttggtg tctgtacgcg aacaggcgcg cccggcggcg
     5641 caacaatcgg aaacggaact gctgcgccag cgggaaaaaa tcaaccgcag cctggatatg
     5701 ctcgaaagtt atctgagcga cgggacgcta aaaacggata cggtcaatct ggcgactatc
     5761 gcgattgcct gtgcggtagg ctatctcaac ttccgccggg tcgcgcccgg ctggtgtgtt
     5821 agccgccccc acctggtcaa actggtcgaa acgctttttc aacgcgaaag ctttgcccgc
     5881 accgaagcgc caaaggcttg acgcgcatta tgtccgcctg agcaaactca cgttacaatc
     5941 ccccttatgt cgatatccct ctcccgccag gagagggcca ccaacagcca ggcattttca
     6001 tgacaagcga aacgcgtaca ctctacagcc agcttcctgc tatcgatcgt ttattgcacg
     6061 atagcgcctt tctttctctg cgcgatcggt atggccatac ccaggtggtt gatctgctta
     6121 ggcggatgct tgacgacgcg cgcgacgtca tacggaatac gcaaacgctt cccgactggt
     6181 acgcagactg ggcgcaagag gcgaaactcc ggctggaaaa tgcggcgcaa agcgcgctgc
     6241 gcccggtgat taacctgacg gggacggtgc tgcacaccaa tcttggccgc gcattgcagg
     6301 cgcaagaagc gattgaggcg gtaacgcagg cgatgcgcgc gccggtgacg ctggaatacg
     6361 atttagatgg cgccgggcgg gggcatcgcg accgggcgct ggcgacgctg ttatgccgta
     6421 tcaccggggc ggaggacgcc tgtatcgtca ataacaatgc ggcggcggta ttgctgatgc
     6481 tggcggcgac cgccagcggc aaagaggtgg tggtttcgcg tggcgaactg gtcgaaatcg
     6541 gcggcgcgtt tcgtattccg gatgttatgc gccaggcggg ctgtacgctg catgaagtgg
     6601 gcaccaccaa ccggacgcac gcgaaagatt accgtcaggc ggtaaatgaa aataccgggc
     6661 tgttgatgaa ggtgcatacc agtaattaca gcattgaggg ctttaccaaa acggtagagg
     6721 aagcggaact ggcggaaatc gggcgagagc tggatattcc ggtggtggcg gatctgggca
     6781 gcggttcgct ggtggattta agccaatatg gcttacccaa agagccgatg ccgcaacagc
     6841 tcattgccgc aggcgtcagc ctggtaagct tctccggcga taagttgttg ggcgggccgc
     6901 aggccgggat catcgtcggc aaaaaagcga tgattgccca actgcaaagc catccgctga
     6961 aacgcgctct gcgcgcggat aaaatgacgc tggcggcgct ggaggcaacg ttacgtctgt
     7021 atctgcaccc ggaagcgttg gcggagaaat tacccaccct gcgtctgtta acccgcagtg
     7081 aagcgtcgat tcgcgaacaa gcgcagcggt tacaggcgcg gttggcggca cgttacggcg
     7141 atgaatttgc gctggaggtt aaaccctgtc tgtcgcaaat cggcagcggt tcattaccgg
     7201 tagaccgcct ccccagcgcc gccatgacct ttaccccgca cgacgggcgc ggtagtcggc
     7261 tggaggcgct ggcggcccgc tggcgcacgc tgcctgtacc ggtcattggc cgaatttatg
     7321 atggccgttt atggctggat atgcgctgtc ttgaagacga aagccggttt atggagatga
     7381 tgctgaaatg attattgcaa ctgccggaca cgtagaccac ggtaaaacga cgttgctcca
     7441 ggcgattacc ggcattaatg ccgatcgcct gccggaagag aaaaaacgcg ggatgactat
     7501 cgatctgggc tacgcctatt ggccgcagcc ggatggtcgt gtgctgggct ttatcgatgt
     7561 gcctgggcat gaaaaattcc tctctaacat gctggcgggc gtaggcggta tcgatcacgc
     7621 tttgctggtg gtcgcctgtg atgacggcgt tatggcgcaa acgcgcgagc atttacagat
     7681 cctacagctg acgggcaatc tccagctcac cgtcgcgctg accaaagccg atcgcgtgga
     7741 cgaggcgcgt atcagcgaag tacgtgaaga ggtgctggcg gcgctcgaca actatggctt
     7801 cgccgatacc gttttatttg tcaccgccgc caatgaagga cgcggtattg cagaacttcg
     7861 cgctcattta cagcagcttc ctgcacgttt acacgccgcg cagcatcgct tccgtctggc
     7921 tatcgaccgt gcgtttacgg tgaaaggggc gggactggtg gtgaccggaa cggcgttgag
     7981 cggagaggta aacgtgggcg atacgctatg gttgaccggc gttaatacgc cgatgcgcgt
     8041 acgaagtcta cacgcgcaaa atcagcctac cgaccatgcg tatgccgggc aacgtattgc
     8101 gctcaatatt gcgggcgatg cggagaagga gcagcttaac cgcggcgact ggctgctttc
     8161 cgatgcgccg gcgggggagg ctttttcccg ggtgatcgtt tctctggcgc ttcatgcgcc
     8221 gctttcccaa tggcaaccgc tacatattca ccatgccgcc agccatgtga ccggtcgcgt
     8281 ctctttgctg gaaggcgcgc tggccgagct gatctttgat acgccgttgt ggctggccga
     8341 taatgacaga ctggtattgc gtgatatttc cgcacgcgcc acccttgccg gcgcacgcgt
     8401 ggtgacgctt aacgcgccgc gccgcggtaa acgtaagcca gattatttgc actggctttc
     8461 aacgcttgcc gatgcgcagg acgatagcgc agcgttggcc attcatctgg aacgcggggc
     8521 cgtcaacctg ccggatttcg gttgggcgcg tcagcttaat cctctcggta tgcgtcagct
     8581 tattgagcaa catggtttta tccaggccgg agacaatctg ttaagcgcgc ccgtcgccgc
     8641 ccgctggcag cgtaagattc ttgatacgct ggcgacctac cacgaacagc accgcgatga
     8701 accggggccg ggacgcgagc gtttacgccg catggccctg ccaatggagg atgaagcgct
     8761 ggttctgatg ctgatcgagc ggatgcgcga cgagggcctg attcatagcc atcacggttg
     8821 gttgcatctg ccggatcata aagcgggatt tagcgatgag cagcaggccg tctggcaaaa
     8881 agtcgaaccg ctatttggcg atgagccctg gtgggtacgc gatctggcga aagagaccgg
     8941 aacggaagaa caattgatgc ggctggtgct gcggcaggcg gcacagcaag gcatcattac
     9001 cgcgatcgta aaagatcggt actatcgtaa cgatcggatt gtcgctttcg ccaatatgat
     9061 ccgcgagctg gatcaagaga gaggatcaac ctgtgcggcg gattttcgcg acaggctgaa
     9121 tgtagggcgg aaactggcca ttcagattct tgaatatttt gaccggattg gatttacacg
     9181 acgtcgtggg aatgatcatt tattacgtga tgcgttatta tttccgcaaa aagaatgaaa
     9241 tggttaaatt aaataacaaa tgaagcaata caattattgc gttgctttat aaaaagcaca
     9301 tcagcaaatg aacctgatgt gctttttatt tttctggctt cttaaaatag ccatcgtgag
     9361 cctattatca gaatagtttt gcccatattc tttgcgcctt attcaggcga ctcacgacga
     9421 gattgtggaa ctttatcgcg cggcgatgta acgcctttgc ccggtggcgc ggacgcttac
     9481 cgggcctgcg tagacgatgc aggccggata gggcgtaaca cgttatcttc ggtcgagctt
     9541 ttgctgcgcc agccagacgg cgcccagcct gcctgcctga tttcccagtt ggcagggctg
     9601 aatcggcacc tggagcgcct cccacatttc aaacgtttca agatgccgcg tcaggagcgg
     9661 gtagagcttt tcctgttcgc ttattcctcc gccgatcagc accacgcccg gatcaaacat
     9721 agagatcacg ctgtaaacgc cgcgtgacag ataacgcgcc cagtcattga ccgcctcacg
     9781 cagatgaaca tcggtcgcca ttcgttcgaa gatcacatcc gcaggcggca tctcttctgc
     9841 aggcagcgcc agagcctggc ggcacgacgc cattaatccg ctggttgacg cgattttatg
     9901 catactttcg ccattattcc cgaccggcat gacgccgaat tcaccggcgt ggaaatgtgc
     9961 gccgcgatac agttctcgtc cgacgataat accgccgcca atgccggttc caatggtgat
    10021 acagaccaga ttgtcataat gctgcccggc gcctcgccac atttcgccca gcgccgcgca
    10081 gttcgcgtcg ttctccacga ccagcggcag atcggttagc ccgctgaaca actccatcag
    10141 gttgacgtca tccaggtatg ccagcgcgcc cgcttttgcc gcatgaccgt tatggggatt
    10201 aatatggccg gggaaactga ccccgattgc cgcaatgtca tagtcctgct ggcaacgcgc
    10261 caccacatcc tgccatttgc gggtaaacgt ggaggcgtcc tctggcgtat cgaattgatg
    10321 atgggttaat tcttcgccgt cactgttaat cacgccatat ttgacgtgag ttcctcccac
    10381 atcaataccg atatattgct gcatagtgtt ctccgtacgt taaacaggca cctgtttagt
    10441 atggctaaaa ccagacggag aaacgtaaag gaaagtaatt cgtgattgct gtcgtaaagc
    10501 gagaaaccat tggcgaaaaa ttcaccagta ccgtctaccc ttgtggagta cctttacaat
    10561 aaggagttgg tcatgacgaa caatccccct tcaacacgta ttcagccaag tgaatacggg
    10621 tacccactga agttaaaagc ccgctatgac aattttattg gcggtgactg ggttgcgccc
    10681 gccgacggcg aatattatca aaacctgacg ccagtgaccg gccagccgct atgtgaagtc
    10741 gcttcctccg gtaaaaaaga tatcgattta gcgctcgacg ccgcgcataa ggcgaaagat
    10801 aagtgggcgc atacgtcagt acaagaccgt gccgctatct tgtttaagat cgccgatcgg
    10861 atggaacaaa acctcgaact gttggcgaca gcggaaactt gggataacgg taaaccgatt
    10921 cgtgaaacca gtgccgccga cataccgctg gcgatcgatc atttccgcta tttcgcctcc
    10981 tgtatacgtg cgcaggaggg cgggatcagc gaagttgata gcgaaaccgt ggcctaccat
    11041 tttcacgaac cgcttggtgt cgtggggcag ataatcccgt ggaactttcc gctgctgatg
    11101 gcaagctgga aaatggcgcc agcgctggcg gcaggtaact gcgtggtgct taaaccggca
    11161 cgcctgacgc cgctttccgt tttactgtta atggaagtca ttggcgatct gttaccgccg
    11221 ggcgttgtca acgtcgtgaa cggcgcgggc ggcgagattg gcgaatatct ggcgacctca
    11281 aaacgtatcg cgaaggtggc gtttaccggt tcgacggaag tgggtcaaca gatcatgcag
    11341 tacgccacgc agaacattat tccggtgacg ctggagttag gcggcaagtc gcccaatatc
    11401 ttcttcgccg acgtgatgga tgaggaagat gcgttctttg ataaagcgct ggagggattt
    11461 gccctgtttg cctttaacca gggcgaggtg tgtacctgtc caagccgtgc gctggttcag
    11521 gagtccatct atgagcgctt tatggagcgc gctattcgcc gggtggagag cattcgcagc
    11581 gggaacccgc tagatagcgg tacacagatg ggagcgcagg tctctcacgg ccagcttgag
    11641 actatcctca attatatcga tatcggtaaa aaagaggggg ccgatattct gaccggtggg
    11701 cgacgcaagg aactggatgg cgaacttaaa gagggctatt accttgagcc taccattctg
    11761 tttggtaaga ataatatgcg cgtctttcag gaggagatct ttggcccggt gctggcggta
    11821 accaccttta aaaccatgga gaaggcgctg gaaatcgcta acgatacgca atatggcctg
    11881 ggtgctggcg tctggagccg caacggcaat ctggcctata agatggggcg cggcattcag
    11941 gccgggcgcg tatggaccaa ctgctatcac gcctatccgg cacatgcggc gtttggcggc
    12001 tataagcagt cgggcatcgg gcgcgaaacc cataagatga tgctggaaca ctaccagcaa
    12061 accaagtgcc tgttggtgag ttattccgat aagccgctgg ggctgttctg acgcaagagg
    12121 taatgcccga tggcgctgcg tttatcaggc ctacaagaat ttatcgcaat atactgatat
    12181 tgcaaatctt gtaggccgga taaggcgcag ccgccatccg gcacagtatt accgctcgtt
    12241 aatccaaatc cgcatttcgc cctcgccacg gttggcccag ctaaaccacg gaatgaatgt
    12301 tagcgtctgc ggctgacgcg atgacggcgc gttatcgtag tgccacaacg cctgatgctg
    12361 cgcatccgcg gcgctttgct tctcgccttc ggcctgaatc agcatcttat gcgcaaaaag
    12421 ccctttgccc tcaaagaccc ggaactcact ctctttcggt agccacagat tatgcagttc
    12481 ttcgccgtta tcggcctgct caaggcaata gaccagcggc ccgcgctgaa tagcgacctt
    12541 accggcgacg tgacgcgcca gcggattgcc atacacgcgg cgaaccggca tcggcagcgt
    12601 caggcttatc gtatcgccct cctgccaggt tcgacggata tgcagataac ctttgcgaat
    12661 atcctgctcc acttccagcc cgttgagcgt cacttttgcc tcagggcacc agtccggcag
    12721 acgtagcgcc agcgtgtgac gtaccggctg cacagaatcg atggcgatct tcacctgctc
    12781 atgccacggg tagttcccgc tgattcgcag tttgagcgcg ccattttcaa ccggtatttc
    12841 catgctgtta cccacgtaca tattgatgta cagcgcatcc gcacgcggcg tgtagatgta
    12901 gtgaccaatg gacgtgagta cgcgggcgat attcggtggg cagcaggcgc agccaaacca
    12961 gcgctggcgg atgggtttaa cgtgatcgta gatatggttg aattttaacg attttggatg
    13021 cacttccagc gggttgacgt agaagaaatg cttgccgtcg agcgccatac cgccgaggac
    13081 ggtgttgtac agcgcgcgct ccatcacgtc ggcgtactgg ctatcggctt ccatttccag
    13141 catccggcgg gcgaacatca tcaggccgat tgaagcgcag ctttccgcat agaccgaatc
    13201 attcggtaaa tcgtaatcgc tgctaaaggc ttcgccgctg ctttgtgaac cgatgcctcc
    13261 ggtgatatac agctgacgct gcgccatatt tttccacagg cgcaggcagt cctggcgttt
    13321 gccttcatcg ttgctcaggc gagcgagatg cgccacgcca gtcatcagat agacaaaacg
    13381 taccgcgtgg ccgattgccg tctgctgctg cgaaattggc agatgcgcct ggctgtaggc
    13441 tttgtctttg accatccacg ccgggccgta ggtatgccag taagaggttt ggccgcgttt
    13501 ttcgtactct tcgtcgtaga agtgcggttg ggcgccgcgc tgcccgataa agtaacttgc
    13561 cagcgtcata tagcgcggct gctctgttac ctcatacaga cgcatcagcg ccagctcaat
    13621 ttccgggtgg cccggataac cgtgcagctg attttcgcca gggccgaaag tgctgtcgat
    13681 atgatcggcc agacgacaaa cgacgtctag cagccgacgc ttgccggtgg cctgaaagaa
    13741 ggcgacgccc gcttcaatca gatgcccggc gcaataaagc tcatggcact ccgccaggtt
    13801 gctccagcgt tcttgcgggg cttttgccgt aaagtacgta ttgagatagc catcgtcaca
    13861 ctgcgcggcg gccaccagtt caatcacctc atcggcggtt ttctcaagct ctgggtcggg
    13921 tttttggcac agtgaccagg caaccgcttc cagccatttc gccacgtcgc tgtcctgaaa
    13981 gaccatgccg taaaagtcgc ccgtctgctg gcctgcggca atgcggaaat tttcaatggc
    14041 atggctgggt tcagcctctg gaatacgatc gtttaacgca tcccactggt aaggaataac
    14101 cacatcgcga accagttgtt gatactgtcc gagtaacgga tcgctgaccg tcagtttatg
    14161 cagatcgact tccagtacgt tcatttcgtg ctccttaagg ctgtagaggt catagatatt
    14221 cctcgctgac ggggtatttt atggcagtaa tttttatttt cgcgttatga cctgattcat
    14281 tttgcccaga tagcggtgag cgacaaggcg ataaaagagt aaaaaaagat gacgattccg
    14341 actcgtattt aaaaatgtga gatggatcga gtgaaatgac tatttttagt taataatcaa
    14401 aaagtaatat gaaatacggt gctgaatgag cgggaaataa catattaatg ctcgaattat
    14461 ccataacatt accgattaaa gtccaaaacg gcggattatt tatttctcgc ggcattgggc
    14521 gtcatcctgc caggcgtctg caatcgtggg aaattatatt tgtggaaaaa ggctgcctga
    14581 aaattcagga agaatgtgtt ttctgtgtcg aagccgggga aagcctgttg ctttggccgc
    14641 atcgccgcca tattggcgtt gaggagtttc ccgccgatct taaattttac tggctccatt
    14701 ttgaggtcaa agcgccggac agcgacccgc gctggctgac gcatctttcc gtgccgcagc
    14761 atacccaggt tgccgatccg caggcgctga ttgcgctttt tcgccagttt atgaacgagc
    14821 aggaaaagca ccagcgcagt ccggcgctgg agttcatcgt gctgctgatt ttgcagcagc
    14881 tcaccgttga cgcccggcag aatgaaaacg ccgaggccgc tggcgtgtcg ctggcctgga
    14941 aagcgcagca gctgattcga acgcactatc acctgccgct ttccagcgcg gttctggcga
    15001 aagaactgca ttgcaatgtg gattatctgg gacgcgttta tcggcgggta tttcacctta
    15061 cgctaacgga agccatccac cgccagcggg tgcgcgaggc ggaaaagttg ctgattagcg
    15121 acgcgcgttc gttaaaagag gtggcggagc ggtgcggttt taatgacgtt ggttactttc
    15181 gccagatctt ccgcaagcac accggcctga cgcctaccgc ctggaagcgg cgctacagta
    15241 aggaacacgt taattcttga gtataatctt tggccctctg acaacgcggt tgcaaactga
    15301 atgcccgatg gcgctttgct tatcgggcct acaagagttc atcacaacgt attgatattg
    15361 caaatcttgt aggtcggata aggcgcagcc gccatccgac acaggctgtg actgccgata
    15421 ttactgcccg taataggcgt tcgcgccatg tttacgcaga tagtgtttat cgagcaattc
    15481 cggctgcata tccggtagct gcggggccag ctggcgcgag aacagcccca tataggcgca
    15541 ctcctcaagc accacggcgt tgtggacggc atcggcggca tttttacccc aggcaaacgg
    15601 gccgtgtgaa tgaactaata ccgccgggat ttgcgccgga tcgagaccgc gctcttcaaa
    15661 ggttttaata atcacctcgc cggtctgata ctcgtactcg ccgttaattt cctcaacggt
    15721 catcagccgg gtacagggga tcgcgccata gaaatagtcg gcgtgggtgg tgccccaggc
    15781 gggcagatcg agcccggcct gcgaccagat cgtcgcatgg cgggaatggg tatgcacgat
    15841 cccaccgatc tgcggatagc ggcgatagag cgccagatgg gtcgcggtat cggacgacgg
    15901 ttttttgttg ccttcaacga ccttaccgct ggcgatctct accaccacca tatcgtcggc
    15961 ggtcatcacc tcatattcga cgccggaagg cttaatgacc atcagcttgc gcgtctcatc
    16021 gaccgcgctg acgttgcccc aggtaaaggt gaccagcccg tgcgccggga gggccaggtt
    16081 ggccgccagc acctcggctt tcagttgctc taacatgtga aacctccttc ctgcatccgt
    16141 gattcaatcc agcggcgggc ctggataatt tccagcaccg gctcgctggc tttctctgtc
    16201 cacatctcaa tcagaaatga accgcgatag ttcagctcat gcagcgtttt gaagatgctg
    16261 acaaaatcaa cgcatccttc gccaaacggc acgtcgcgga actggccggg gttgtcaccg
    16321 gtcaccggca gcgtgtcttt caggtggatc gcggcgatac ggtcgatacc cagcttcagc
    16381 tcggcggtca cgtcgttccc ccaggcgctg aggttgccga cgtctggata aacggtgaac
    16441 cacggtgacg aaagcatctc gtcccacttt ttccacttgc tgatggagtt cataaacgcg
    16501 gtatccatga tctccaccgc cagcatcacc tgcgccgctg cggcctgttc caccgcccac
    16561 gccagccctt cggcgaaacg ttgctgggtg ccttcgtcgt gctcttcgta atagacgtcg
    16621 taacctgcca actggatggt gcggatcccc aggtcgcgcg ccaggcgaat ggctttggtc
    16681 atgatttcac gcgcccgctg gcgtaccgct tcgtcgcggc tgccaaaagg gaagcgacga
    16741 tgggcggaga ggcacatcga cgggatggcg acgccgcttt ccagcatcgc gttcaccagc
    16801 gaagcgcgtt gggccgaggt ccactccagg cgtgagagac gttcgtcggt ttcatccacc
    16861 gacatctcaa caaaatcaaa accgcagctt tttgccagca ccagccgctc tggccaactg
    16921 agatctttcg ccagtgcttt ctcgtaaata cctaatggat gattacgcat gcttttctcc
    16981 ccaaatggcg tcaatttggg cgtggaattc ggcggcgacc tgcgccggat gggcggcacc
    17041 tgccagcgca cgtccggcga taaatgcctt aacgttaatg tcgcggaaca gcggcagatc
    17101 cgctggggta atgccgccgg taatcgatag ttcaaggccg atgtcggaca acgccttcat
    17161 acgcgccagg tccgcttctc cccactgctg cccgctggcc tgcgcatcgt gtccgcggtg
    17221 gtaaatcgcc tggcgaaccc cgacgcgata ccagtctcgg gcgtcgtcca gcgtccagtt
    17281 gccgaacagt tccatttgaa tttcaccgcc gcaggattgc gcgacggcat ggcctttctc
    17341 gacggtcgcg agcggcgcgg cgcagatgat agtcatccag ttagcgccag cgctaaaagc
    17401 ctgctgcgcc agggtttcac cggcatcggc cactttccag tcggcgacga tgattttttc
    17461 cgggcactgc gctcgcaggg ctttcaccgc gctaaggcct tcggttaaac aaaggatggt
    17521 tccggcctca acgatatcga catgatcctg tagcagggcg acatcgcgct gggctgcttc
    17581 cagactggtg tggtcgagcg ccagttgcag taatggtcgg ctcataatgc gtgctcctta
    17641 atacgggcgt gatagccctg tagtgcttca atcaaatcct ggtattggcg gtatttgcgc
    17701 tggtagaggg cgtgcgcggt catgtccggc agcagcgtgc gtaccgggtg ctgcaggtcg
    17761 cgttgggcct cgtggaaatc gcgatatacg ccggtgccga cgcgggctgc cagcgccgcg
    17821 ccgaagcagc cggtctcctc cacctgcggc agctcgatgc gtaacccgct gacgtccgac
    17881 agcatctgca tccagacgtc ggagtgggcc ggtccgccgg taacgcgcag ggcgcaaacc
    17941 tcggtaaagc gttcacgcat gcggttgagg tgggtcatat ggctgaagac cacgccttca
    18001 tagagcgcct gtagcaggtg cgcgcggttg tgcagcgcct gcatgccata aaagccgcag
    18061 gtcatctcca gcccggcatt gctgccgtag agaaacggga gaaaaaaaag gtcgctaccg
    18121 gctttcggca ggctggcaac cgcctggttg atctcgtcaa aagagaggta gccccactgg
    18181 gcggtgaacc attcaaggtt gccggaagag gtcgggctgg cttcgtgaac gatatactgc
    18241 ccgtcattga cgtagcggcc atagacgtaa ggatgggcct catggtcgcg cagaccgtga
    18301 gcgatgccgc tggtgacggc ccaggtcccc atcaccgcat tgagcgttga ttcatcctca
    18361 ataccggcgc aaagggcggt ggaaaccacg tcaaacaggc cgccgacgac gggggtaccc
    18421 gccgccagac cggtgatagc ggccgcctga gcggtgatct ccccgcatat ttcggctgaa
    18481 cccaccacgg ggggcagcgc gctatcgatt tcactgatgc ccagccattc ggtcaggcgc
    18541 gggtcgtact ggcccgtcgc catgttgtag aggttggact cggagatatt gctctcctca
    18601 cagcctttca cgccggttaa gcaccagcgc agatagtcat gcgtcatcat gacgctgcct
    18661 atctgcgcgt agcgctgcgg ctcattctct tttacccagc gtaaaaggga gaccggatgc
    18721 ccggtccaca gggtttgccg ggtcagtggg tagagttttt gcggaaccgc ttctttttgc
    18781 cagcgctgga caatttccat ggcgcgacga tcggaagaga gtatcgcttt acctaatggc
    18841 cgatcgcttt tatctaacag gaacaggcct ttcccttggg ctgaaatacc cagaccgcgg
    18901 atttgtgagc cgctcacccc cgtgtgcgtc agcagtttgc tgatgaccga agcgcactgt
    18961 tgccacagtt cggtcatatc gcgttcaacc cagcctggct gcgggcttaa agcgtgcagc
    19021 ggcaggcgtt gcaccgctac ttcccggcct gcgccatcgt acaacccggc ttttagccaa
    19081 ctcccaccac aatctaaccc cagccagtaa ttgctcatga cttattgcac ctcgtccacg
    19141 gctttcagga ggtcggcgcc ctgcgggttg tctttcagga acatatcgcg cacctggctg
    19201 cccagcgcat cactgaaggc tttacggtcg atatcggtca ggacttcaac tccggcttct
    19261 ttcatgccat cgataatttt ttgctgatct tcggcgacca gtttgcgctg gtagtccccc
    19321 gcttctttgg cggaactcag cagtgcctcc tggaactgcg ggcttaaagc gtcgaatttg
    19381 gctttattga tcaccagcag cagaggcgaa taggcgtgat gagtgaggga gaggtatttc
    19441 tgtacctcat agaatttcgc tgaccacacg acgttgatag ggtgttcctg ggcatcaatc
    19501 gtacgggttt cgaggccggt atagacttcg gagaatggca tcggaatagg gttcgcgccg
    19561 aagattttaa aggccgcgat attcattgga ctgttgttag tgcggatttt taagcctttc
    19621 aaatcgcccg gcgtttttac cggcgcgcgg gagttggtga cgtcgcgcca gccgttttcc
    19681 cagtaggcga ggacttttaa cccttttgaa tcgagtgatt ttttcagttc atcgccgact
    19741 ttaccgtcga gcgttttatg cgcatgcgag gtatcgcgaa acaggaaggg gacatcaagt
    19801 aagttgaata caggggccag gccggtgaaa ttgttcgaac cggacatttc catatcaata
    19861 gttccgccgc gcaccccgct gatcattgcc tgagcgttac ctaatgtgct gtcaggaaag
    19921 agttttagcg ttaattcgcc gttggttttt tcttttaata attcgttaaa ttttttcgcg
    19981 gcaatatgtt gggagtcagt ttgcggtgtt tcataaccaa aacgtaaaga ttgcgccgcc
    20041 agagacgaca cgctgaaaac cgtcagacca gctatcaata atgaacgagc aataacgtgt
    20101 aatttcataa tattatcctt taattaatcc atttaagcgg tgtgataatt agctcgggaa
    20161 taaaaataaa taaaaccagc agcgacatca gtacgacaac gtaagggaat acgcctctta
    20221 ccgcgtcatc aaatttcaat tttgctaccc cggaaataac gttgaggacg ttgccaacgg
    20281 gcggtgtgat taatccaata gagcagttaa taatgaacat gacgccgaaa taaatcgggt
    20341 caatattggc ttctttaact aatggcaata atacaggggt aagaattaac accgttggcg
    20401 tcaaatccat caccataccg acgaccataa ttgagatcat aatgacgata aataagagtc
    20461 gcggagagtc gaccagcggc tgcagcaaat ctgacactat catgggtaat tccgcgatcg
    20521 taatcagcca ggcggatacc tgggccgcgg ccaccagaaa catgacgact gacgtcgttt
    20581 tggcggcatt gaccagcacg tggtagagac tggaaaacgt taattcccga tagataacca
    20641 cggcgacaaa gagggcgtaa aacgcggcga ccgcccctgc ctccgttggc gtgaaaagtc
    20701 cggaacggaa gccgccgatg ataatcaccg gtaaaaacag cgcccagata cctgaaacca
    20761 atgaatacca gatttcacgc ggtgttgctt taggctgaga agggagattt aatcgcccgg
    20821 cctgccacca ccaggtgagc ataagcgccg cgcccatcat gatgcccggt gcgatcccgg
    20881 ccataaacag cttgctgatc gacaagccgc tggaaacgcc gaagataata aaaggaatcg
    20941 aggggggaat aattggcgca atgatcccgc cggaagcgat taacccaacg gagcggttga
    21001 tcgggtagtt tgcggagcgc atcatcggca ccagcagcgc ggcgaccgca gcggtatctg
    21061 ctaccgcaga gccggaaagg ctggccataa tcattgccgc aataacgccc acgtagccca
    21121 ggccgccggg cttatggccg accagcttca tcggcaggtc gacaattcgc tttgacaggc
    21181 cgcccgcgtt catgatttca ccggccaaaa caaaaaaggg aatggccagt agggagaaac
    21241 tgtccgcgcc gttaaccagg gtttgcgcca taatctgcac gtcaaacata tccaggtatg
    21301 ccatcagagc agcgccgcaa agcagcagcg accaggcgat gggtaaacct atcgcgatcc
    21361 cgccgagcag gcagcagaga aatatcacca cggccatgat taggctcctt gctgtggttg
    21421 ttgaaaggaa tcgttacgcg ttattaagtg ataaagccga cgcagctcga ttaacgcgat
    21481 ggcaacgctt gtgggcagac aggcgatata catcaggccg atcggtaaac cgaggattgg
    21541 cgagtgatcg ctccagtcct gcaacgcttt ttgcaggctg ccccagccta atgcgatgca
    21601 taacaataaa atcagcgaat gtgtcagcag cgagagtcga cgctgattcg ctggcgaaag
    21661 tttttccacc acaaaagtga cctgaacgtg agcgttatcc ataaatgcaa cgatggcgcc
    21721 aataaacgtc agccatacaa atagataacg tgatagttca tctaccgaca aaatactgct
    21781 ctcaaaaccg taacgtaaaa taacgttaat aaatacaatg caggaaagta cggcaattaa
    21841 taccgcaagt atgccctcaa gtacccgctt cataacgact ccatcaggtt atagaaactt
    21901 atttctttcg atgctgaata gtggaactta atttcttatg tttggtttat attaggtcgg
    21961 cgcaacgttg agttgcaggc cgagaattaa ggtgatgatg tttaattcag gttagcggcg
    22021 tgtggccttt ttcatcatgt taataccatc gcgtaatata tttatgcggt gattaatatc
    22081 ggcactggca ttgatttcca acaatttaat accggtaaac tgcaacagtt cgggagcggc
    22141 ggcggtaatc agttctttaa catgtttctc cgtcatcaga ctttgtggac agaaaggtgc
    22201 aaacggagca tggaggtcct gccattcgcc gtattctcca tccagcgttg taccggagaa
    22261 catcagcgcc ccgagttttc cagcctgttt ggcctgctgc gtgtggatca gcggtagaga
    22321 ggtatcccgc ccttcaatag ccgagcgcgc ccagttaatg cagacgctta tgtcatagtc
    22381 ggcaatagtt tccagtacgt ttaccaacgg taagaatcct ttgcgcggtg cggggccggt
    22441 catcgcgtcg cagtgttcaa gcaccaggtc gcaggaccag tcccagttgg caatctcttt
    22501 taatgagcgc gcaaaggcgt cggttgcctg cgccacgttc ggattgcccg ccagaggagc
    22561 ggcatgaagc tcaagggcta tgactttgcc ggtattgttc ccattgattt tattgatctt
    22621 ctgatgcaga tgacgatagt actccacgca ggctttacgc tgttcctcgt cactggacgc
    22681 taatccaaaa ccgccgtttt cgctacggcg acgcatggtt tccattatcg cggtgaccac
    22741 gatttgccag tttcccggtg tatggcgcaa taaccactcg tcgccgagcg ggtgaagatg
    22801 ttcaagacaa ggctgctcca gcccccggat atccggagta tcagagagtt gccgccagaa
    22861 ttccgtctct tcctcttcac tcttctggtg aaatgagggt gcacaagggt acgcaccgat
    22921 aatataaccg gtattatttt tcattttgtg ctccagtaaa ctctatttta taaaacgtct
    22981 atggcgactt ttacgactat tttccgtatc ggcgtagcaa tgcttttatt acaaccggga
    23041 cgatgaacat cctgcgggaa aaacagggca taacttcccg gtatcatttc aatgaatgat
    23101 tcatgttcac tgtcgtgata aaaaataata tcgcgctgtt ctaataatga ctcgctgatt
    23161 tgattattac cggtatcaat ggcaacccca attttctctt caccccatgc cagaaactga
    23221 atatccagat agcggcgatg gacttccgga cgattttcag cagcatcgcg ggtggtcata
    23281 tcgataatct gcgcgaaggt atttttgccg tcgatttcca ctacgccggg ttccagcgtg
    23341 cgaaagtcgg tggtacgtaa aaagtgaagc gctttctcga tcgcggctgg caaatgacat
    23401 ggatttggct gcgcgatatg tccaaaaatc atgatgtggc tccttacagc gcctggattt
    23461 tagcccagac gctgtcgtca atggtgatac cgttacagcg gctgtcatcc agcaatttgg
    23521 taaattcgtg gccgggcagc cgaatcgcga cgttgtcgtc agcacgttca gcagtggtga
    23581 tgaaatccat aatccgctgc agtttggcat cgcgggttgc gccatcgatc agcttatcca
    23641 cttctatggc gatgaaaatc tgcgaaacgc catactcatc gctgttttcc tgggtcactt
    23701 cggcaacgga agagccgttg gaaagcaggg tggcaatcat gtccagcaca atcgacagac
    23761 cagatccttt ccagtaaccc atcggtaaaa tgcggtgatt tttctcgatc acgcccggtt
    23821 ctttggtcaa ctgaccgtta tcgtcgaaac cgccgtccac cggcagttcg cggcccgcca
    23881 gacggttaac ttctaacatc ccgtaggaga acatcgacat cgacatatct accatcgtga
    23941 tcggcgtaga cgggatggcg acgatcagcg gattggtacc gatacggcac tctttcgcgc
    24001 cccacggcgg catgacggcg atggagttgg tccagcaaat gccgatatag cctttttccg
    24061 ccgcctgcca gccgtagctg ccgccgcgca tccagtggtt agcattacgt aacgccacca
    24121 ggccaatacc atgatcggaa gccagctcga tggcccggtc catcatcttt ttcgccgtca
    24181 ggttgccgat agcgcgctga gcatcccact gttcgatggc gccgaggctg gtaacccgct
    24241 gcggtttagc atcaggaata atgtcgccgt tatccagttg ctggatgaag cggggaaagc
    24301 ggttcacgcc gtgggaatag acaccggact cggtggtgcg agcgaacatt tccgcgcagg
    24361 cgtcggcggt atcttccgca atattccgcg accgcaagac gcggtagaag gcccctttta
    24421 actcttcgaa agttactttc atccctgttc tcctggtcga ttgttagaaa ttttagtatg
    24481 tttttttgtc gataaatttc ataatgcgaa atgtagttcc aaatatatag atcaaaaatt
    24541 gacatggcaa cgccagagaa gctttttaaa aacgattaaa atcatcgggt tatgtttttt
    24601 atgctgatat cgtgaactgc aacacacttt gagctaccat ctgatcgccc aagaaaggag
    24661 agagttttct gatgagccag aacaacgata aagagaagcc tgcggggagt cagagcctgt
    24721 ttcgtggcct gatgttgata gaaattttga gtaactaccc gaacggttgc ccactggcgc
    24781 acctgtcgga gctggcgggg ttgaacaaga gtaccgtcca tcgtttgttg caggggcttc
    24841 aatcctgcgg atacgtgacg ccagcgccgg cggccggaag ctaccgtctg acgacaaagt
    24901 ttattgccgt cggccaaaaa gccctgtcat cgctgaatat catccacgtt gcggcaccgc
    24961 accttgaggc gctcaacctg gccaccggcg agacggtgaa tttttccagc cgtgaagatg
    25021 atcacgctat cctgatttat aagctggaac cgaccaccgg tatgctgcgc acgcgtgcct
    25081 acattggcca gcatatgccg ctgtactgct cggcgatggg gaaaatttat atggcgtttg
    25141 gtcagccgga ttatgtggcg tcttactggg aaagccataa agatcagatc cagccgctga
    25201 ctcgtaatac cattaccgat ttaccagcaa tgtacgatga gctggcgcaa attcgtgaaa
    25261 ccagcatggc gatggatcgc gaagaaaatg aactgggcgt ttcctgtatt gctgtgcctg
    25321 tgtttgatat tcaccatcga gtgccttacg ccatttctat ttcactgtcg acgtcacggc
    25381 taaaacagat cggcgagaaa aatctgctca aaccgttgcg tgaaaccgca caggctatct
    25441 ctaatgagct gggatttacc gttcgcgaat aagacagctc gccaggtttt atcaggcatc
    25501 tgacaaaatt tgtccgtttg cgtagtggga tcaaagcggc ggggaatggc tctctggcat
    25561 tctggcgttt taacgcaggg ggagaacaat gaaccggttt attatggcgg atgcgtcggc
    25621 gtgtatcggg tgtcgtacct gcgaggtcgc ctgcgtggtg tcgcaccagg aacagcagaa
    25681 tagcgcggcg gtgacgacgg cggactttgt gccgcgtatc cgggtgataa aagaggatag
    25741 cttcaccacg gccacggtct gccatcagtg tgaggacgcg ccgtgcgcga atgtctgccc
    25801 ggtacaggcg attcgccgtg atcgggggca tatcttcgtg acgccatcgc gctgcattgg
    25861 ttgtaaaagc tgtatgctgg cttgcccgtt tggcgcgatg actgtggtgg cgtccgcgtc
    25921 aggcgcgcag gcgattaaat gcgatctttg ctggcatcgg gaagcggggc cggcgtgcgt
    25981 ggaagcctgc ccgaccagtg cgttacagtg cgttgacgca acacacgtgc agcgccagcg
    26041 cctctattct caacctttct gaacatcgtt ccggcctgca taatggccgg aataaccgtc
    26101 agccttcacg ccaggcgcgt tctatctctt ctgccagaat ttttacgccc gcctcgattt
    26161 tatccggttc aggcacgtag ttcatccgca tacactggtg tgtgtgcggc cagggtttat
    26221 ccagtccggg aaagaaatag tggcccggca ccatcagcac gccgcgcgct ttcaagcgtt
    26281 gatagagtag ctcggtggta atcggcagat ctttaaacca cagccacaaa aatattgcgc
    26341 cttctggttt atgaatcagg cagcgttctt cggataaata gcgacgaatg atcgcgatcg
    26401 tctgttgaac gcgctgatag tagaaaggtt tgataaccgt ttccgacagc cgcagcagat
    26461 cgttacgctt aatcatttcg cacatcatcg ccgggcccat gcccccgggc gcaaggctga
    26521 tgatgccgtt catgttggca atggcggtaa tcgtcttatc attggcgatg ataatcccgc
    26581 agcgggaacc gggcagcccc agctttgaga ggctcatgca taggataata ttggggttcc
    26641 acagcgggcg cgcctcgcta aagataatgc ccggaaacgg tacaccgtaa gcgttatcaa
    26701 tcaccagtgg gatgttgtgc tgattcgcca gtctgtccag cttcatcagc tcttcgtcgg
    26761 tgataacgtt accggttggg ttggtcgggc gcgagacgca aatcatcccc gtttcttcgc
    26821 cgatgtgcag atgctcaaaa tcgacgtgat acttaaactg gccttccggc agcagctcaa
    26881 tattcgggcg cgccgaaacg aagaggtcgt cttccagacc ggaatccgca tagccgatgt
    26941 attccggcgc aagcgggaat agtacctttt tcgtactgcc gtcggcgcga cgtccggcga
    27001 agagattaaa taagtagaaa aacgcgctct gactgccatt tgttagcgca atattctgtg
    27061 gttcgatatc ccatcccagc gtttcacgta gcagtacggc cagtgcattc agtagcgccg
    27121 tttttccctg gggaccgtca taattacaaa gcgcatcagc ggctttgccg ctttctacca
    27181 tctctgtcag tagcgtctgg aaataatcct gcattgcagg gatgtgtgcc gggttaccgc
    27241 cgccaagcat gatggcgcct ggcgtgcgta agccgtcgtt gagatcctcc atcaggcggg
    27301 taatgcctga atggcgggta aatttatcgc cgaaaagtga aaatgtcata acgggtgatc
    27361 tatcgaactg tctgtcaaag tggataacca taacgctaca aatggcgggg cgcaaatggg
    27421 ggacaggcgg tggtattgat gttttatgct acaaattttt atcagtttag ttttttattt
    27481 tgaagaggtt accggtacgc gaggggaccg gtagcgccac gattagcggc ggcccgccca
    27541 gacgaccatc accgtatcgt cgccgtactg gcgtacaaaa ccgtacccgt gttttagcgt
    27601 cagcgtggtt tgttggcctg cgccgatggc gggatgtctg gcgcggaact ggctaatacg
    27661 ctgccagtgc gcgacggctg cggctgactt tccgctcacg tcctgccagt tcatatcaga
    27721 acgggtgcct tgcagcgggt cggagccggt ggggccgaag ggacgagcgg attcatcgcc
    27781 gtaaaagatc tgcaccgcgc ctggcgaaag cagcagcagt tccgccgcct tatcaccgcc
    27841 ctcacggaaa aggcgcgtat catgcgagga gaggtaactt aatacgttga aatcctgcat
    27901 tttatccgcc atctgctgcc agactggccc catttccgcc aggcaatcga ccgctttcgc
    27961 cgcctgctcc tgataatcaa aattgatcat cgcgtcgaaa ccatagcgat aataatcact
    28021 tttcatgacg ccgtggcccc acgcttcgcc agtcatccag aacgggctat catccagcgc
    28081 tttgtccgga ttggcctgct tccattcatg taacgccgcg ctggcctggg tttttagctg
    28141 ttgccaggca ggaagctcaa cgtttttggc agtatcgatc cggaacccgt caatgccgta
    28201 atcatgcacc cactggctta accagtgagt cagataatcc cgtggcgtat agccctcaat
    28261 gaactttgct ttagtatcgg gtttgttggc atagaacacg ggtaggccgg aaggcgtggt
    28321 agattccgtt tttatatccg gcaggaaggc cagcgacagg gttaaatcgt caaatcccgg
    28381 actgtcgtag tcgccaatat cggtacgaat ccactttttc ccccaccatt tttcccaggc
    28441 ggcgctgtcg ctgaagttga tgtagtcgtt aaagctgtgc cagctttgtc cggcggccgg
    28501 tcgccagttt gtccagcgat cgccgagaat tttttgccgt tccgcgccgg ataaatagag
    28561 cgcgccgaac tgatactcct gcatatccgc cagcgtggcg taaccggcat gattcattac
    28621 tacgtcaaat aaaatacgga tgccgcgctg gtgcgcgccg tcgaccagcg cgcggagatc
    28681 ggcttcgctg cccatattgg catccagcgt cgtccagtcc tgagtgtaat agccgtgata
    28741 ggcgtaatga ggaaaatcgc cttttgttcc gccgccgacc cagccgtgga tctgttcaaa
    28801 cggcgagctt atccacaagg cgttcacgcc taattgctgt agatagtcca gttgactcgt
    28861 caacccgcgc aaatcgccgc cgtggaaagt gccaatctct tgcataccat ccttatggcg
    28921 accataactg tggtcgttgg ttggatcgcc attgcgaaag cgatccgtaa gcacaaaata
    28981 aacggtggcg ttgcgccagt taaaaggcgc tgacgcatgg gtttccgcgc gttccagcaa
    29041 taaaagcccg tggctgtcgg caggtagcag cgtgattttt ccgttttgga cggtatcgat
    29101 ttgaccactg taataatcgc gcactaccgt cccttccgga aaggtttggc gaacatccag
    29161 cgtgagcggc gaaccatccc agacgggaca ctggtaggcg agctgcgtgg tgcgttcagg
    29221 ttcagttttt atcgataaca acagggtcgg cgtaccggat cgggtatcta ccgttatcgt
    29281 atagtcgcca tctttaaaca gacgccattg cggcggcgcg ccttcgcagg gttttaacga
    29341 caacatttgg ttgagtttta tagcgccgga gggctgccag cactgctggt caatatggag
    29401 cgttaacgcg cgtgtacctt ttgttaatgc agcatggctg gtaaagcgtc cggtttcctg
    29461 cgtcgagagc gtcggaaaac cgggcgaggt ccatgatgag gcgatcgcga taccgggtat
    29521 cagcgtcaga gcgaaggcgg caagtttcat cacgctatcc tttgtgggca atattcatca
    29581 gcttgcctgg tttttaggcg aatgaactcc tccccagcag agagtcgcgc aggaggaggc
    29641 gcgagggtga gcgacgaggc gcaaaaaaac gcctctattt gcgataaacg ccgcatttta
    29701 ttggcattat tgctgtctgt tatcgttaat agttgacata gtttcggatt aagactattc
    29761 cctgaggtgc tttttaagcc tatttttgct agaatttggg gttcaaacct caacttcgtg
    29821 aaaaataaaa ggtgttggaa tgtatcaatc cgaccaggag acctaatgat attgactccc
    29881 atgcgacgat atggggcaat gattcttatg ttactcacca tcgcattttc gggtgaggtg
    29941 ctggcaaaga cgcgcgcaac acaaacgagt caaaagtccc acataactga gacaagttat
    30001 aaacaggtta gcagtaaaca agagtattct cgcaatagtg caaagagcag ttcacttcct
    30061 gatttgcgaa aatacccttc cggaaccccc agaaaaaaag cgtttctccg gaccgttatg
    30121 ccttacatca ccagccaaaa tgccgcgatt accgcggacc gtaattggct gatctcaaaa
    30181 cagtaccaga accgctggtc gccgtctgag cgcgcgcgta tgaaagatat cgcgaagcgc
    30241 tataaagtga gctggtccgg caacacgcgt cgtattccgt ggaatacgtt gctggagcgc
    30301 gtcgacatta tcccaaccag catggtggcg acgatggcgg cggcggaaag cggctgggga
    30361 acctctaaac tggcgcgtag caacaataac ctgttcggca tgaagtgcac gaaagggcgt
    30421 tgtaccaata cgccgggtaa ggtgaaaggt tactcgcaat tcgcgtcggt tgaggagtcg
    30481 gtgagcgcgt atgtcgccaa cctgaacacg catccggctt attcttcttt ccgcaagtcg
    30541 cgcgcccaac tgcgtaaggc ggatcaggaa gtcaccgcca cggcgatgat tcataagcta
    30601 aagggttact ctacccaggg ggcgcgctat aacaactact tgttcgcgat gtaccaggac
    30661 aaccagcgtc tgatcgccgc gcatatgtaa ttctgtgtgc cggatggcgc tacgctatcc
    30721 ggcttacaag gcatctgtag gctggataaa ctacaacaac gcttcactat gctggtcgcg
    30781 atactcctta ggcgtagtga cgtactcctt tttaaacacc gaatagaaat attgcagcga
    30841 cgggtagccg cacatttgcg aaatttcgtt tatcgccaac gtggtggaaa tcaacaaact
    30901 acgcgctttt tccagctttt cggcgtggat cagcgcatgt atcgtctcgc caacttcttc
    30961 cttaaaacgt ttttccaggt ttgaacgtga aatcccaacc gcgtccagca cctgctcgac
    31021 tttaatgccc ttacaggcat ggttacgaat aaagtgcatc gcctggataa ccgccggatc
    31081 ggtcagggag cgatagtctg tcgagcggcg cgcaatgacg cgcaccggcg gcaccagaat
    31141 gcgctgtaac ggcatctctt cgcgcgccag caaacggtgc agcagcttcg ccgcctgata
    31201 gcccatttgc cgcgccccct gcgcgacgga ggaaagcgcg acgcgcgaca gataacgggt
    31261 taactcttcg ttatcaatac cgataacgca aagtttttcc ggcaccggaa tatgcaggtg
    31321 ttcgcaggcc tgcaatacgt gacgggcgcg ggcatccgtt acggcaatga tgccggtttg
    31381 cggcggcagc gtctgaagcc agtcggcgag gcgattttgc gcgtgctgcc agttttccgg
    31441 cgcggtttcc agcccctgat agactacgcc gcggtatttt tcctcggcga ccagctggcg
    31501 aaaggcgtat tcccgttccg ccgcccaatg tttgcggctg gagtcgggca aaccgtaaaa
    31561 cgcgaagcgg ttaacgcctt tttcttttaa atgcaggaaa gcgctttcaa cgagcgcatg
    31621 attatcggtg gcgatgtaat gaacggcggg ataattttca gcaagatggt aagaaccgcc
    31681 gaccccgaca atgggtacgt cgacatcggc caataattgc gcgatatcgt catcatcgta
    31741 atcggcaata acgccgtcgc ctaaccactc tttaatgtta tcgatacggg cacggaaatc
    31801 ttcctcaata aatatatccc attcggattg cgaggcttgt aaatattcac ccaccccctc
    31861 cactacctga cggtcatagg ctttattcgc gttaaataac agagtgatac ggtgacgttt
    31921 atcaaacatg aggatatatc ctgcaaaagt gaacctggac tcatggatac tatcaaaacg
    31981 gctgacataa cggtctggcg aatgatgaca aattattttg cgcctgaaac gttatgcgaa
    32041 attcatcaca gcaaacggcg gatgacaatt gtcatttctt atctatatat tacggttttt
    32101 tgtttatttg ccaggattcg atcgcgatcg cttttttctt ctgtggtttt cagcgttttt
    32161 ttgagagcca gagcacattt ggggattctc ttaatagcgg tgtgaaataa cgtaattgag
    32221 caataaatca ggaaattcca gtatgacgtt atgtcgttta cttgccgtct tatctgatta
    32281 tggagctcac tatgcaggct tattttgacc aactcgatcg tgttcgctat gaaggccctc
    32341 aatcgactaa cccgctggca tttcgtcatt acaatcccga cgagctggtt ttaggtaaac
    32401 gtatggaaga tcacctgcgt ttcgcggcct gttactggca taccttctgc tggaacggcg
    32461 cggatatgtt tggcgtaggc gcgtttaatc gtccgtggca gcaaccgggc gaagcgctgg
    32521 agctggcgaa acgcaaagcg gacgtggcgt ttgaattttt ccacaaactg aatgtgcctt
    32581 tttactgctt ccatgacgtg gatgtgtcgc cgaaaggcgc gtcgttgaaa gaatataaaa
    32641 acaacttcgc gcagatggtg gatgtgctgg cggcgaaaca ggagcagagc ggcgtaaaac
    32701 tgctgtgggg aacggcgaac tgctttacca acccgcgcta tggcgcaggc gccgccacta
    32761 acccggaccc ggaagtcttt agctgtgcag cgacgcaagt ggttacggca atgaacgcca
    32821 cgcataaact gggcggcgaa aattacgtac tgtggggcgg acgcgaaggt tatgaaacgt
    32881 tgctgaatac cgatctacgc caggaacgcg aacagattgg ccgctttatg caaatggtgg
    32941 ttgagcacaa acataaaatg ggtttccagg gcacgctgct gattgaaccg aaaccgcagg
    33001 aaccgacaaa acatcagtat gattatgacg ttgcaacggt ctatggcttc ctcaaacagt
    33061 tcggcctgga aaaagagatc aaagtgaaca ttgaggcgaa ccacgccacg ctggcgggcc
    33121 attcgttcca ccatgaaatc gcaaccgcta tcgcgctggg tatttttggc tccgttgatg
    33181 ccaaccgcgg cgatgcgcaa ctgggctggg ataccgatca gttcccgatt agcgttgaag
    33241 agaacgcgct ggtgatgtac gaaatcctga aagcgggcgg attcacgacg ggcggtctca
    33301 acttcgacgc caaagttcgt cgccagagca ccgataaata cgatctgttc tacggtcata
    33361 tcggcgcgat ggatacgatg gcgttgtcac tgaaaatcgc cgcgcgtatg gtcgaagacg
    33421 gcgagttgga taaacgcgtg gcgaagcgct atgccggctg gaatggcgag ctggggcagc
    33481 agattctgaa aggacaactc tccttaggcg aactggcgca gtatgcggag cagcaccatc
    33541 tggcgccggt acatcaaagc ggtcatcagg agctgttaga aaatctggtt aaccgttatc
    33601 tgtttgataa ataactctat ctaccgggcg actccgcgtt agcccggcct gtagtcgtga
    33661 ttagcccggt aagcgtagcg ctgccgggcg ctttcagtaa aggaacccac actatgtata
    33721 tcgggatcga tcttggtaca tcgggtgtaa aagctatcct gttgaatgag cagggcgatg
    33781 tgctggctac gcatactgaa aaactgaccg tatcgcgtcc gcatccctta tggtcggaac
    33841 aggaaccaga gcagtggtgg caggcgacgg atcgtgcggt taaaggttta ggtcggcaac
    33901 agtcgttaag tggcgtccgg gcgttgggca tcgccggaca aatgcatggc gcgacattac
    33961 ttgatagccg tcagcaggtt ctgcgaccag cgattttatg gaatgacgga cgctgtagcg
    34021 aagagtgcgc ctggctggaa aaacaggtgc cgcagtcgcg agcgataacc ggtaatctga
    34081 tgatgcccgg ttttaccgcg cccaaattag tttgggtgca gcgccacgaa ccggatattt
    34141 tctaccagat agacaaggtt ctgctgccga aagattttct gcggctgcga atgacaggcg
    34201 tctttgccag cgatatgtcg gatgcggcgg gaacgatgtg gctggacgtg aaaaagcgcg
    34261 actggagcga cgttatgctc aacgcctgtc atttaacccg acagcagatg ccagcgttat
    34321 ttgaaggtag tgacattacc ggaacgttgc tgccagaggt cgccagcgca tggggaatgc
    34381 cagcagtacc tgtggtggca ggcggcggcg acaatgcggc tggcgcggtc ggcgtaggaa
    34441 tgatcgatgc cggacaggcg atgctctcac tcggaacatc gggcgtctat tttgccgtca
    34501 gcgacggctt tctgagtaaa ccggagagcg cagtacacag tttttgccat gcgctgccgg
    34561 aacgctggca tttaatgtct gtgatgttga gcgccgcctc ttgtctggac tgggcggcta
    34621 aactcaccgg gcaggagaac gtcccggcgc tgattgccgc cgcacagcag gcggatgagc
    34681 atgccgattc gatctggttt ttgccgtacc tgtccggcga gcgcacgccg cataataatc
    34741 cgcaggcaaa aggcgttttc tttggtttaa cccatcagca tggcccggcg gaactggcgc
    34801 gggcggtact ggaaggcgtg ggatatgctt tggcggacgg tatggatgtg gttcacgcct
    34861 gcggcgtcaa acccgccagc gtgacgctta tcggcggcgg agcgcgcagc gaatactggc
    34921 gtcagatgct atctgatatt agcgggctac agcttgatta tcgtactggc ggcgatgtag
    34981 ggccagcgct gggcgcggcg cgtctggcgc aaattgcggt gaataaacag actccgctcg
    35041 ccgatgtatt gccgcagttg ccgctggagc aggcgcatta tcctgatgcg cagcgtcatg
    35101 cggtttatca acaacgtcgt gaaaccttcc gtcgactcta tcagcagctg ttgccgttga
    35161 tgtcataagt cagaatgcct ttcagttttg gctgaaaggc atttcccgta aatattgatt
    35221 ctattgaatt atatcgaagt aagtatgtgt gttttctgat ttttatatta ttgctgagca
    35281 ggcgcctttt tcatcgctat ttcttcgctt aatgtgtctc actcaaccac aaggagagtg
    35341 agatggacga tcacgttgca cgcaggaaac ggatattcgg cctgggaatg ttagttgtcg
    35401 gtgcagtggt atacttggtg ggattgtggc caggctgtca tacattaagc gaaaagggat
    35461 atttttttgc ggcaatcgtc atgtgcggtt ttccagtctt aattcgccag gaacacacgg
    35521 ggaatgaccg cttgctttct cgttgtaaat ctttgctgtt gcttggcatc ggcatggtcg
    35581 cggtcggcgt atttaacctg gcgctggcgg gcgcgctgaa aatactgtgt ctggtggcgc
    35641 tgggggtcag tatatatgga accgatcttt acgcttccta cagtgatgat gaatgatggc
    35701 cggagccatc attgtcgttt agctaaccca tttccgttta tcaatacgct gtaacagcat
    35761 ggaaagtagc aggcttcctg tcaccgtcgc ggcaaaaacc cacacgatgt ctaacggcgg
    35821 ccaacgtttt aattccagac cattagtacg tagcgcatgg ataatcagcg cgtggaaacc
    35881 ataaataccc agcgagtggc gggagataag ccccagtcta ggtaacgtcc gcgcattcag
    35941 cttattttta actaccgtga acagtgagac ggcgcaaata aacaccatgg gaccgcaata
    36001 cagataccag gtatcggcaa aatttccgcg ccagcgtaat tcatgcaatg tgccgcgaga
    36061 aataacaaat accgcgatga tgaacagggc agcgcagata agcgtcagcg atggcttttg
    36121 cgtctccatc attccaatgg cgcggcccag gataccgtag agaatgtagt agaacgtgtc
    36181 gccgctgata tacagattga tgggcaacca ttcaacgccg ccgatttttt gcggcacagt
    36241 atttgggtta gcaataatac caatgatcac catcagcatc aggagcattt tgccgctcac
    36301 gttttttacc tggattaatg gcgataccag gtagatcacc gtaatcgcaa agaaaaacca
    36361 caggtggtaa aacacgggtt tttgcagcgc attttttagc gaaagctcga cgttgatcga
    36421 agtaaaaagt gaaatgtaag ccagggcgac aacgctgtaa aagataaggc acagggcaat
    36481 acgtaaaaaa tgccgcggtt gcgcgcagcg ctcgccaaaa aaagatagcc tgaaatcata
    36541 aaaaacaggg gaacgctaac gcgcgaagcc gaattcagga cattcgcaat atcccagttt
    36601 agcgggctga cgctgtgggc gttggtgatg taccacgttg tagtatggat catcactacc
    36661 attaaacagg cgatccctcg caggttatca atccagttaa ttttaggctg catcagttcc
    36721 tcagcttccg tttcaataga gttccagcgc ggtggctcac tggaaaaatc cgactttcta
    36781 cgctacatct tgtgatggcg taaggagatt cgcacaatgt ttctgttacc cacaaacctt
    36841 aataataaga ctgaccagca aaccagacgg taataaaaat gataatgaag tatttctgta
    36901 ctgtgatgat agccatcgct ctggtgggat gcacagcgac accgccaccg acgcaaaaag
    36961 cccagcagag taaagtgagc ccaacacgca cgctggatat ggaagcattg tgtaaagctc
    37021 aggcggcgca gcgttacaac actggcgcac agaaaattgc tgttaccggc ttcgaacagt
    37081 ttcaggggag ctatgagatg cgtggtaata ccttccgtaa agagagtttt gtctgctctt
    37141 ttgatgcaga tgggcagttt ttacatcttt ctatgcggta aaagccgcgc ctggtgaggt
    37201 gtgatgccgc gaaatccggt aattttcgct aaacaaaccg gtttcatact gtatatctcg
    37261 catccagcgg gtatactggc tccttccttt aaatccacac gtatccagca cgaaataata
    37321 tgcaaaagtt tgataccagg accttccagg gcttgatcct gaccttacag gattactggg
    37381 ctcgccaggg ctgtaccatt gttcaaccat tggacatgga agtcggcgcg ggaacttctc
    37441 atccaatgac ctgcctgcgc gcgctggggc cagagccgat ggcgactgcc tatgtgcagc
    37501 cttctcgtcg tccgaccgat ggccgctacg gcgaaaaccc gaaccgctta cagcactact
    37561 atcagttcca ggtagtgatt aagccgtctc cggagaatat tcaggagctg tacctcggtt
    37621 ctctgaaaga gctgggtatg gacccgacca ttcacgacat ccgtttcgtg gaagataact
    37681 gggagaaccc gacgctgggt gcctggggac tcggctggga agtgtggctg aatggcatgg
    37741 aagtgacgca gttcacctac ttccagcagg tcggcggcct ggagtgcaag ctggtgaccg
    37801 gtgaaatcac ctacggtctg gaacgtctgg cgatgtatat ccagggcgtg gacagcgttt
    37861 acgacctggt ctggagcgat ggcccgctgg gtaaaactac ctacggcgac gtgttccatc
    37921 aaaacgaagt tgagcaatcc acctataact ttgaatacgc cgatgtggat ttcttattca
    37981 cctgcttcga gcagtatgag aaagaagccc agcagctact agcactggaa aacccgctgc
    38041 cgctgccggc ctacgagcgt attctgaaag ccgcccacag cttcaacctg ctggatgcgc
    38101 gtaaagccat ctccgtcacc gagcgtcagc gttacatttt gcgcattcgc accctgacaa
    38161 aagcagtggc agaagcatac tacgcttccc gtgaagccct cggcttcccg atgtgcaaca
    38221 aagataagta agaggcggct atgtctgaga aaacttttct ggtggaaatc ggcactgaag
    38281 agctgccacc aaaagcactg cgcagcctgg ctgagtcctt tgctgcgaac tttactgcgg
    38341 agctggataa cgctggcctc gcacacggca ccgttcaatg gtttgctgct ccgcgtcgtc
    38401 tggcgctgaa agtagctaac ctggcggaag cgcaaccgga tcgtgaaatc gaaaaacgcg
    38461 gcccggcgat tgcccaggcg ttcgatgctg aaggcaaacc gagcaaagca gcagaaggct
    38521 gggcgcgtgg ttgcggtatt accgttgacc aggctgagcg tctgactacc gataaaggcg
    38581 aatggctgct gtatcgcgcc tacgtgaagg gcgaaagtac cgaagcactg ctgccgaata
    38641 tggtcgcgac ctctctggcg aagctaccga tcccgaaact gatgcgctgg ggtgcaagcg
    38701 acgtacactt cgtgcgtccg gttcacaccg taaccctgct gctgggcgac aaagtcattc
    38761 cggctactat tctgggcatt cagtccgatc gcgtgattcg cggccatcgt tttatgggcg
    38821 agccggaatt cactattgac aatgccgatc agtatccgga aatactgcgc gagcgcggga
    38881 aagtcatcgc cgattacgaa gaacgtaagg cgaagattaa agccgatgcc gaagaagccg
    38941 cgcgtaagat cggcggtaac gctgacttaa gcgaaagttt gctggaagaa gtggcttcgc
    39001 tagtggagtg gccggtcgta ctgaccgcga aatttgaaga gaaattcctc gctgtgccgt
    39061 ctgaagcgct ggtttacacc atgaaaggtg accagaaata cttcccggtg tatgcgaacg
    39121 acggcaaact gctgccgaac tttatcttcg ttgccaacat tgaatcgaaa gatccacagc
    39181 aaattatctc tggtaacgag aaagtcgttc gtccacgtct ggcagatgcc gagttcttct
    39241 tcaacaccga ccgtaaaaaa cgtctggaag ataacctgcc gcgcctgcaa accgtgctgt
    39301 tccagcaaca gctgggtacg ctgcgcgaca aaactgatcg catccaggct ctggctggct
    39361 ggattgctga acagattggt gctgacgtta atcacgctac ccgtgcgggc ctgctgtcta
    39421 agtgtgacct gatgaccaac atggtcttcg agttcaccga cacccagggc gttatgggga
    39481 tgcactacgc gcgtcacgat ggcgaagcgg aagatgtcgc ggtggcgttg aacgagcagt
    39541 atcagccgcg ttttgctggt gatgacctgc cgtccaaccc agtggcttgt gcgctggcga
    39601 ttgctgacaa gatggatacc ctggcgggta tcttcggtat cggtcagcat ccgaaaggtg
    39661 acaaagaccc atttgcgctg cgtcgtgccg cacttggcgt gctgcgtatt atcgttgaga
    39721 agaacctcaa ccttgatctg caaacgctga ccgaagaagc cgtgcgtctg tatggcgata
    39781 agctgactaa cgccagcgtg gttgatgatg tcatcgactt tatgctgggc cgtttccgcg
    39841 catggtatca ggacgaaggt tactccgtcg acaccatcca ggctgtactg gcgcgtcgtc
    39901 cgacccgtcc ggcagatttt gatgcccgca tgaaggcggt gtctcatttc cgcaccctgg
    39961 aagaagcctc tgcgctggcg gcggcgaaca agcgcgtctc caacatcctg gcgaaagcca
    40021 ctgagccgct gaacgatatc gtccacgcct ccgtactgaa agaagcggcg gaaattgagt
    40081 tggccagaca tctggttgtg ctgcgtgata agcttcagcc gtactttgcc gatggtcgtt
    40141 atcaggaagc gttgattgag ctggcggcac tgcgcgcgcc ggtggatgaa ttcttcgaaa
    40201 atgtcatggt gaacgcggaa gagaaagata tccgtatcaa ccgcctgacg ctgttgtcga
    40261 aactacgcga actgttcctg caggttgcgg atatttcgtt actgcaataa gcgttcagtt
    40321 aaataaacaa aaacctgc
//
LOCUS       DAJVBX010000014        38076 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.014, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000014 DAJVBX010000000
VERSION     DAJVBX010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 38076)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38076)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38076
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.014"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            47..808
                     /locus_tag="OPV72_000671"
     CDS             47..808
                     /locus_tag="OPV72_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCR9913046.1"
                     /translation="MRICSNEPCIVLLTEKDTWLRVNGKEPISLKANHMAILACENNV
                     IDISSLNSVLVIQVSRNNIKDYLQFLNKDLSHLPVWQRNADPLLTATCLTPDIFRVAA
                     RYSAMETPDEIVSERTRALLFTVLSRFLDHKKFISLLMHMLRSRISDSVYHIIQSDIH
                     KDWNLSAVASCLCLSPSLLKKKLKNENTSYSQIITTCRMRYAVNQLLMDGKNISQVSQ
                     LCGYNSTSYFISVFKEFYGMTPLHYVSQHRERSAA"
     gene            948..2285
                     /gene="adiC"
                     /locus_tag="OPV72_000672"
     CDS             948..2285
                     /gene="adiC"
                     /locus_tag="OPV72_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine/agmatine antiporter"
                     /protein_id="HCR9913047.1"
                     /translation="MSSDADAHKVGLIPVTLMVSGNIMGSGVFLLPANLAATGGIAIY
                     GWLVTIIGALALSMVYAKMSSLDPSPGGSYAYARRCFGPFLGYQTNVLYWLACWIGNI
                     AMVVIGVGYLSYFFPILKDPLVLTLTCVAVLWIFVLLNIVGPKMITRVQAVATVLALV
                     PIVGIAVFGWFWFKGETYMAAWNVSGMNTFGAIQSTLNVTLWSFIGVESASVAAGVVK
                     NPKRNVPIATIGGVLIAAVCYVLSTTAIMGMIPNAALRVSASPFGDAARMALGDTAGA
                     IVSFCAAAGCLGSLGGWTLLAGQTAKAAADDGLFPPIFARVNKAGTPVAGLLIVGVLM
                     TIFQFSSMSPNAAKEFGLVSSVSVIFTLVPYLYTCAALLLLGHGHFGKARPLYLLITF
                     VAFVYCIWAVIGSGAKEVMWSFVTLMVITALYALNYNRIHKNPYPLDAPVKQD"
     gene            2419..4062
                     /gene="eptA"
                     /locus_tag="OPV72_000673"
     CDS             2419..4062
                     /gene="eptA"
                     /locus_tag="OPV72_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase EptA"
                     /protein_id="HCR9913048.1"
                     /translation="MLKRFLKRPVLGQIAWLLLFSFYIAVCLNIAFYKQVLQDLPLNS
                     LRNVLVFISMPVVAFSVVNSVLTLASFIWLNRLLACIFILVGAAAQYFILTYGIIIDR
                     SMIANMMDTTPAETFALMTPQMVLTLGLSGVLAAVIAFWVKIRPATPRLRSGLYRLAS
                     VLISILLVILVAAFFYKDYASLFRNNKQLIKALSPSNSIVASWSWYSHQRLANLPLVR
                     IGEDAHRNPLMLKGDRKNLTILIVGETSRGDDFSLGGYPRDTNPRLAKDDVIYFPHTT
                     SCGTATAISVPCMFSDMPRKHYDEELAHHQEGLLDIIQRAGINVLWNDNDGGCKGACD
                     RVPHQNVTELNLPGQCIDGECYDEVLFHGLEDYIDHLKGDGVIVLHTIGSHGPTYYNR
                     YPPQFKKFTPTCDTNEIQNCSQQQLINTYDNTVLYVDYIVDKAINLLKSHQDKFTTSL
                     VYLSDHGESLGENGVYLHGLPYSIAPDTQKHVPMLIWLSKDYQQRYQVDQACLQKRAS
                     TLDYSQDNLFSTMLGLTGVQTTYYQAADDILQPCRRLSE"
     gene            4059..4727
                     /gene="pmrA"
                     /locus_tag="OPV72_000674"
     CDS             4059..4727
                     /gene="pmrA"
                     /locus_tag="OPV72_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator PmrA"
                     /protein_id="HCR9913049.1"
                     /translation="MKILIVEDDTLLLQGLILAAQTEGYACDGVSTARAAEHSLESGH
                     YSLMVLDLGLPDEDGLHFLTRIRQKKYTLPVLILTARDTLNDRISGLDVGADDYLVKP
                     FALEELHARIRALLRRHNNQGESELTVGNLTLNIGRHQAWRDGQELTLTPKEYALLSR
                     LMLKAGSPVHREILYNDIYNWDNEPSTNTLEVHIHNLRDKVGKSRIRTVRRFGYMLVA
                     TEES"
     gene            4737..5807
                     /gene="pmrB"
                     /locus_tag="OPV72_000675"
     CDS             4737..5807
                     /gene="pmrB"
                     /locus_tag="OPV72_000675"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     PmrB"
                     /protein_id="HCR9913050.1"
                     /translation="MRFQRRAMTLRQRLTLTIGLILLVFQLISTFWLWHESTEQIQLF
                     EQALRDNRNNDRHIMHEIREAVASLIVPSVFMVSLTLLVCYQAVRRITRPLAELQKEL
                     EARTADNLTPIAIHSSTLEIESVVSAINQLVTRLTTTLDNERLFTADVAHELRTPLSG
                     VRLHLELLSKTHNVDVAPLIARLDQMMDSVSQLLQLARVGQSFSSGNYQEVKLLEDVI
                     LPSYDELNTMLETRQQTLLLPESAADVVVRGDATLLRMLLRNLVENAHRYSPEGTHIT
                     IHISADPDAIMAVEDEGPGIDESKCGKLSEAFVRMDSRYGGIGLGLSIVSRITQLHQG
                     QFFLQNRTERTGTRAWVLLKKA"
     gene            complement(5815..5904)
                     /gene="pmrR"
                     /locus_tag="OPV72_000676"
     CDS             complement(5815..5904)
                     /gene="pmrR"
                     /locus_tag="OPV72_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LpxT activity modulator PmrR"
                     /protein_id="HCR9913051.1"
                     /translation="MKSYIYKSLTTLCSVLIVSSFIYVWVTTY"
     gene            complement(5974..7476)
                     /gene="proP"
                     /locus_tag="OPV72_000677"
     CDS             complement(5974..7476)
                     /gene="proP"
                     /locus_tag="OPV72_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline transporter ProP"
                     /protein_id="HCR9913052.1"
                     /translation="MLKRKKIKPITLGDVTIIDDGKLRKAITAASLGNAMEWFDFGVY
                     GFVAYALGKVFFPGADPSVQMIAALATFSVPFLIRPLGGLFFGMLGDKYGRQKILAIT
                     IVIMSISTFCIGLIPSYATIGIWAPILLLLCKMAQGFSVGGEYTGASIFVAEYSPDRK
                     RGFMGSWLDFGSIAGFVLGAGVVVLISTIVGEENFLEWGWRIPFFIALPLGIIGLYLR
                     HALEETPAFQQHVDKLEQGDREGLQDGPKVSFKEIATKHWRSLLSCIGLVIATNVTYY
                     MLLTYMPSYLSHNLHYSEDHGVLIIIAIMIGMLFVQPVMGLLSDRFGRRPFVIMGSIA
                     LFALAIPAFILINSNVIGLIFAGLLMLAVILNCFTGVMASTLPAMFPTHIRYSALAAA
                     FNISVLIAGLTPTLAAWLVESSQDLMIPAYYLMVIAVIGLITGISMKETANRPLKGAT
                     PAASDIQEAKEILGEHYDNIEQKIDDIDQEIAELQVKRSRLVQQHPRIDE"
     gene            7944..8279
                     /locus_tag="OPV72_000678"
     CDS             7944..8279
                     /locus_tag="OPV72_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phnA family protein"
                     /protein_id="HCR9913053.1"
                     /translation="MSLPHCPQCNSEYTYEDNGMFICPECAHEWNDAEPAQESDELIV
                     KDANGNLLADGDSVTIVKDLKVKGSSSMLKIGTKVKNIRLVEGDHNIDCKIDGFGPMK
                     LKSEFVKKN"
     gene            8399..8842
                     /gene="yjdN"
                     /locus_tag="OPV72_000679"
     CDS             8399..8842
                     /gene="yjdN"
                     /locus_tag="OPV72_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family metalloprotein YjdN"
                     /protein_id="HCR9913054.1"
                     /translation="MPLSPYLSFAGNCADAIAYYQQTLGAELLYKLSFGEMPPSAADN
                     EEGCPSGMRFPDTAIAHANMRIAGSDIMMSDASASGTAHYSGFTLVLDTQDVAEGKRW
                     FDNLAAQGQIEMDWQETFWAQGFGKVSDRFGVPWMINVVKHQPAT"
     gene            8994..9428
                     /gene="phnO"
                     /locus_tag="OPV72_000680"
     CDS             8994..9428
                     /gene="phnO"
                     /locus_tag="OPV72_000680"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoalkylphosphonate N-acetyltransferase"
                     /protein_id="HCR9913055.1"
                     /translation="MPVCELRHATTEDTDSVYALICELLKNELDYQAFRDGFAANLLD
                     PNLHYRLALRNGEVVGMISLHMQFHLHHANWIGEIQELVVLPQMRGQKVGSQLLAWAE
                     EEARQAGAELTELSTNIKRRDAHRFYLREGYKQSHFRFTKAL"
     gene            9686..10594
                     /gene="lpxO"
                     /locus_tag="OPV72_000681"
     CDS             9686..10594
                     /gene="lpxO"
                     /locus_tag="OPV72_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid A hydroxylase LpxO"
                     /protein_id="HCR9913056.1"
                     /translation="MFAAIIIGIFIISVIYAHSRGVEKQKLSRQLFDHSTFMAPINMF
                     MTRFSTLPAKQPYFDTTAFPELQKLTENWQVIREEALRLQHHIKAAQANNDAGFNTFF
                     KRGWKRFYLKWYSDAHPSAETLCPITTKLVNSIPSIKAAMFAELPPGAYLGKHRDPYA
                     GSVRYHLGLSTPNDDRCFIEVDRQRHSWRDGEAVIFDETYVHWAENKTEQTRIILFCD
                     IERPMKWRWAQSVNHWVGASLMSAASSPNDENDRTGAINRIFKYVHAARDAGQRLKKK
                     NRTLYYALKYLVIAAIFAAIILFSLL"
     gene            10933..13080
                     /gene="fdhF"
                     /locus_tag="OPV72_000682"
     CDS             10933..13080
                     /gene="fdhF"
                     /locus_tag="OPV72_000682"
                     /EC_number="1.17.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:11350..11352,aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase subunit alpha"
                     /protein_id="HCR9913057.1"
                     /translation="MKKVVTVCPYCASGCKINLVVDNGKIVRAEAAQGKTNQGTLCLK
                     GYYGWDFINDTQILTPRLKTPMIRRQRGGKLESVSWDEALNYVAERLSAIKAKYGPDA
                     IQTTGSSRGTGNETNYVMQKFARAVIGTNNVDCCARVUHGPSVAGLHQSVGNGAMSNA
                     INEIDNTDLVFVFGYNPADSHPIVANHVINAKRNGAKIIVCDPRKIETARIADMHIAL
                     KNGSNIALLNAMGHVIIEENLYDKAFVASRTEGFEEYSKIVEGYTPESVEEITGVSAQ
                     EIRQAARMYASAKSAAILWGMGVTQFYQGVETVRSLTSLAMLTGNLGKPSAGVNPVRG
                     QNNVQGACDMGALPDTYPGYQYVKFPENREKFAKAWGVESLPAHTGYRISELPHRAAH
                     GEVRAAYIMGEDPLQTDAELSAVRKAFEDLELVIVQGIFMTKTASAADVILPSTSWGE
                     HEGVFSAADRGFQRFFKAVEPKWDLKTDWQIISEIATRMGYPMHYNNTQEIWDELRHL
                     CPDFYGATYEKMGELGYIQWPCRDTSDADQGTSYLFKEKFDTPNGLAQFFTCDWVAPI
                     DKLTEEYPMVLSTVREVGHYSCRSMTGNCAALAALADEPGYAQINTADAARLGIEDEA
                     LVWVHSRKGKIITRAQVSDRPNKGAIYMTYQWWIGACNELVTENLSSITKTPEYKYCA
                     VRVEPIADQRAAEQYVIDEYNKLKTRLRESAMG"
     gene            13257..13946
                     /locus_tag="OPV72_000683"
     CDS             13257..13946
                     /locus_tag="OPV72_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HCR9913058.1"
                     /translation="MKPLIALMLFMTFFAHAADPEPGSQYLQAAEAGDRRAQYFLADS
                     WLSYGDLNKAEYWAQKAADNGDADACALLAQIKITNPVSLDYPDAKKLAEKAANAGSK
                     AGEITLARILVNTQAGRPDYPKAISLLQKASEDLDNDSAVDAQMLLGLIYANGVGIAA
                     DDEKAAWYFKRSSAISRTGYSEYWAGMMFLNGEPGFIEKNKQKALHWLNLSCLEGFDT
                     GCEEFETLTNG"
     gene            complement(14104..15414)
                     /gene="gltP"
                     /locus_tag="OPV72_000684"
     CDS             complement(14104..15414)
                     /gene="gltP"
                     /locus_tag="OPV72_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate:proton symporter GltP"
                     /protein_id="HCR9913059.1"
                     /translation="MKNLKVSLAWQILLAMVLGILLGSYLHYHSDSREWLIANLLSPA
                     GDIFIHLIKMIVVPIVISTLIVGIAGVGDAKQLGRIGAKTILYFELITTVAIILGITL
                     ANVFQPGSGIDMSQLATVDISKYQNTTAEVQSHAHGLMGTILSLVPTNIIASMAKGDM
                     LPIIFFSVLFGLGLSSLPATHREPLVTVFRSISETMFKVTHMVMRYAPVGVFVLIAVT
                     VANFGFASLWPLAKLVLLVHFAIIFFALVVLGIVARLCGLSIWILIRILKDELILAYS
                     TASSESVLPRIIEKMEAYGAPASITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGID
                     LSLWQEIVLVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMA
                     RTALNVVGNALAVLVIAKWEHKFDRKKALAYERDVLGKFDKTAQ"
     gene            complement(15759..16379)
                     /gene="nrfG"
                     /locus_tag="OPV72_000685"
     CDS             complement(15759..16379)
                     /gene="nrfG"
                     /locus_tag="OPV72_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme lyase NrfEFG subunit NrfG"
                     /protein_id="HCR9913060.1"
                     /translation="MSQSEHSTVPLRPMPVKRLTAAAVLMVAVCIGGYMLTPKWQAVR
                     SEQQRLADPLRDFTNPQTPEAQLSRLQEKIRANPQDSEQWARLGEYYLYRNAYDNALL
                     AYRQALRLRGDNAQLFAALATVLYYQSGQHMTPATREMINKALALDATEVTAQMLLAA
                     DAFMQADYAQAVSLWQTLLDANSPRVNRAQLVEAINLAKLLQNRQK"
     gene            complement(16376..16885)
                     /gene="nrfF"
                     /locus_tag="OPV72_000686"
     CDS             complement(16376..16885)
                     /gene="nrfF"
                     /locus_tag="OPV72_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012134579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme lyase NrfEFG subunit NrfF"
                     /protein_id="HCR9913061.1"
                     /translation="MRKLLTALPDGGVSALSGLQDAQTVGRISVAPSGRKFLLLTIVL
                     FLITFATHAQVVDTWRFDNPQQQEKALSIAGQLRCPQCQNQNLLESNAPVAVSMRHQV
                     YSMVAEGKSEAEITAWMTDRYGDFVRYNPPLNEQTLLLWALPCLLLLLVGVVVWRVRK
                     RQHAEEGEQ"
     gene            complement(16878..18614)
                     /locus_tag="OPV72_000687"
     CDS             complement(16878..18614)
                     /locus_tag="OPV72_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016507453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme lyase CcmF/NrfE family subunit"
                     /protein_id="HCR9913062.1"
                     /translation="MHNLDIFLPEAGFLALLLSLGVNVLTPLATWCGMAQHWRGVMRL
                     TTCGAWTAFTLLLLAFAILFSCFLTSDFSVVYVAQHSHSQLSWGLKLAAVWGGHEGSL
                     LLWALLLSGWTVLFAWRSRHESDALFPLTLSILSLIMASLLLFIVLWSDPFLRIFPPA
                     MEGRDLNPMLQHLGLILHPPLLYLGYGGLMTAASVALASLLCGGFNAATAWVCWRWAL
                     LGWCALTLGIILGSWWAYCELGWGGWWFWDPVENASLLPWLAASALLHSLYVSRQRGS
                     FRHWSLLLAILTLILSLLGTLIVRSGILLSVHAFALDNVRAVPLFILFAALSLASLAL
                     YGWRAREPYPATRLGGGKCETLILATLLLFSAVLLIVLVGTLYPMIYGLMGWGRLSVG
                     APYFNRVTLPFGLLMLVVIVLATIRSRKVSVHRQLPALLAHTGVFIFAAGIMVSSGSR
                     HEISLNLSPGQQVVLAGYTFRFERLDLEAKGNYTSEKARITLWRNEKRIGSLQPERRF
                     YAARRQQMMEPGIHWNLLHDWYAVMGEKTGADRYAMRLYVQTGVRWIWGGGLLMVCGA
                     LLSGWRGRKRDA"
     gene            complement(18607..19563)
                     /gene="nrfD"
                     /locus_tag="OPV72_000688"
     CDS             complement(18607..19563)
                     /gene="nrfD"
                     /locus_tag="OPV72_000688"
                     /EC_number="1.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c nitrite reductase subunit NrfD"
                     /protein_id="HCR9913063.1"
                     /translation="MTSASAFHFASLVWDWPIAIYLFLIGISAGLVTLAILLRRFHPE
                     AGGSDSTLLRTTLVLGPGAIILGLLILVFHLTRPWTFWKLMFHYSFTSVMSMGVMLFQ
                     LYMVVLILWLAKIFEKEVIALQQRWLPRLEIVQKVLTLIAPFHRALETLMLVLAVLLG
                     AYTGFLLSALKSYPFLNNPILPVLFLFSGISSGAAVALIAMALRHRSNPHSTEARFVH
                     RMEVPVVWLEIFLLAAFFVGLALGDDGKMRALAAALGGGFWSWWFWLGVVGLGLIIPM
                     LLKPWANRSVTFHGVLAVCGASLTGVLLLRFFILYAGQLTVA"
     gene            complement(19560..20231)
                     /gene="nrfC"
                     /locus_tag="OPV72_000689"
     CDS             complement(19560..20231)
                     /gene="nrfC"
                     /locus_tag="OPV72_000689"
                     /EC_number="1.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c nitrite reductase Fe-S protein"
                     /protein_id="HCR9913064.1"
                     /translation="MSCTRRQFITRVGALAAVSGMAGRVVANTLNINGVRYGMVHDES
                     LCIGCTACMDACREVNNVPEGVSRLTIIRSEPQGTFPDVKYRFFRHSCQHCDHAPCVD
                     VCPTGASFRDAASGIVDVNPDLCVGCQYCIAACPYRVRFIHPVSKTADKCDFCRKTNL
                     KAGKQPACVESCLTKALTFGNLDDPNSDISRLLRQKTTYRYKLALGTKPKVYRVPFNY
                     GEVSQ"
     gene            complement(20228..20794)
                     /gene="nrfB"
                     /locus_tag="OPV72_000690"
     CDS             complement(20228..20794)
                     /gene="nrfB"
                     /locus_tag="OPV72_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418495.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c nitrite reductase pentaheme
                     subunit"
                     /protein_id="HCR9913065.1"
                     /translation="MSVLRSLLTAGVLASGLFWSLSGITATPTPQESDQRWTVTQQRN
                     PDAACLDCHKPDTEGMHGKHTGAINPNNKLPITCTNCHGQPSLHHREGVKDVMRFNDP
                     MYTVEQQNSVCMSCHLPEQLQKAFWPHDVHVTKVTCASCHSLHPQQDTMQTLNEKGRI
                     KICVDCHSDQRTNPHFNPASVPLLKEQP"
     gene            complement(20906..22342)
                     /gene="nrfA"
                     /locus_tag="OPV72_000691"
     CDS             complement(20906..22342)
                     /gene="nrfA"
                     /locus_tag="OPV72_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-forming nitrite reductase cytochrome
                     c552 subunit"
                     /protein_id="HCR9913066.1"
                     /translation="MARKTLRARRFFSLIFPFFFITSVYAEQTPVSAKTVTVEAKNET
                     FAPQHPDQYQSWKATSEQSAREDALAEDPRLVILWAGYPFSRDYNKPRGHAYAVTDVR
                     ETLRTGAPKTAEDGPLPMACWSCKSPDVARLIQQEGEDGYFHGKWARGGPEIVNDLGC
                     ADCHNTASDDFAQGKPAITLSRPYAERAMEAIGKPFDKAGRFDQQSMVCGQCHVEYYF
                     DGKNKAVKFPWDEGMKVENMEQYYDAIAFSDWTNSLSKTPMLKAQHPEYETWSAGIHG
                     KNNVTCIDCHMPKVQNAEGKLYTDHKIGNPFDNFAQTCANCHTQDKASLQKVVAERKQ
                     AIHDLKIKVEDQLVHAHFEAKAAWDAGATDAEMKPILNDIRHAQWRWDLAIASHGIHM
                     HAPEEGLRMLGSAMDKAADARTKLARLLATKGITHEIPLPDISTKEKAQKAIGLNMQQ
                     INAEKQDFLKTVVPQWEDQARKNGLLSQ"
     gene            22774..24732
                     /gene="acs"
                     /locus_tag="OPV72_000692"
     CDS             22774..24732
                     /gene="acs"
                     /locus_tag="OPV72_000692"
                     /EC_number="6.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase"
                     /protein_id="HCR9913067.1"
                     /translation="MSQTHKHAIPANIADRCLINPEQYETKYKQSINDPDTFWGEQGK
                     ILDWITPYQKVKNTSFAPGNVSIKWYEDGTLNLAANCLDRHLQENGDRTAIIWEGDDA
                     SQSKHISYRELHRDVCRFANTLLDLGIKKGDVVAIYMPMVPEAAVAMLACARIGAVHS
                     VIFGGFSPEAIAGRIIDSSSRLVITADEGVRAGRSIPLKKNVDDALKNPNVTSVEHVI
                     VLKRTGNDIDWQEGRDLWWRDLIEKASPEHQPEAMNAEDPLFILYTSGSTGKPKGVLH
                     TTGGYLVYAATTFKYVFDYHPGDIYWCTADVGWVTGHSYLLYGPLACGATTLMFEGVP
                     NWPTPARMCQVVDKHQVNILYTAPTAIRALMAEGDKAIEGTDRSSLRILGSVGEPINP
                     EAWEWYWKKIGKEKCPVVDTWWQTETGGFMITPLPGAIELKAGSATRPFFGVQPALVD
                     NEGHPQEGATEGNLVITDSWPGQARTLFGDHERFEQTYFSTFKNMYFSGDGARRDEDG
                     YYWITGRVDDVLNVSGHRLGTAEIESALVAHPKIAEAAVVGIPHAIKGQAIYAYVTLN
                     HGEEPSPELYAEVRNWVRKEIGPLATPDVLHWTDSLPKTRSGKIMRRILRKIAAGDTS
                     NLGDTSTLADPGVVEKLLEEKQAIAMPS"
     gene            24971..25285
                     /locus_tag="OPV72_000693"
     CDS             24971..25285
                     /locus_tag="OPV72_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF485 domain-containing protein"
                     /protein_id="HCR9913068.1"
                     /translation="MNDQIYQRIEDSARFRELVEKRQRFATILSVIMLAVYISFILLI
                     AFAPGWLGTPLHAGTSVTRGIPIGVGVIVISFVLTGIYIWRANGEFDRLNNAVLHEVK
                     AL"
     gene            25282..26931
                     /gene="actP"
                     /locus_tag="OPV72_000694"
     CDS             25282..26931
                     /gene="actP"
                     /locus_tag="OPV72_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation/acetate symporter ActP"
                     /protein_id="HCR9913069.1"
                     /translation="MKRVLTALAAALPFAAHAADAISGAVERQPTNWQAIIMFLIFVV
                     FTLGITYWASKRVRSRSDYYTAGGNITGFQNGLAIAGDYMSAASFLGISALVFTSGYD
                     GLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRILSACGSLVVVAL
                     YLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFG
                     ASFMAFMVMKHVGFSFNNLFTEAMAVHPKGTAIMSPGGLVQDPISALSLGLGLIFGTA
                     GLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAIMLVGANPAYKDAAG
                     ALIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVF
                     RKGATEREELKVSKITVLVLDVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLS
                     MYWSKLTTRGAMLGGWLGLLTAVVLMILGPTIWVQILGHEKAIFPYEYPALFSISVAF
                     LGIWFFSATDNSAEGNREREQFRAQFIRSQTGFGVQQGRAH"
     gene            complement(26970..27659)
                     /locus_tag="OPV72_000695"
     CDS             complement(26970..27659)
                     /locus_tag="OPV72_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HCR9913070.1"
                     /translation="MNNVQLSVLCLVITLGIYFANKRLYRRFRKLPLMPLVLTPALLV
                     LMLVFGHISWQNYISESHWLLWLLGPATIAFAVPVYDNLAIIKRHWMSLTAGVVTATV
                     VAVTSSVWLARLFTLSDEIQRSLAVRSVTTPFALAAAEPLGGQPDLVALFVVVTGVFG
                     MAVGDALFLRLSIREGMAKGAGFGAASHGAGTARSYELGQQEGVVASLVMMLSGVVMV
                     LAAPLVARVMF"
     gene            complement(27652..28062)
                     /locus_tag="OPV72_000696"
     CDS             complement(27652..28062)
                     /locus_tag="OPV72_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HCR9913071.1"
                     /translation="MAVAISRVTPAVVQRLQVPVQVLLYAGLFIFSQYLVSWLHLPLP
                     ANLVGMVLMLALIVCRIIPLSWVRAGARWLLAEMLLFFVPAVVAVVNYAHLLLVDGWR
                     IFSVIAISTLMVLGATAWVVDKVYRYEMSRLNRE"
     gene            28166..29053
                     /locus_tag="OPV72_000697"
     CDS             28166..29053
                     /locus_tag="OPV72_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCR9913072.1"
                     /translation="MDIRTLRYFVEVVRQQSFTRAAEKLFVTQPTISKMLKNLEDELN
                     CTLLIRDGRKLLLTDTGRVVFERGLAILAEFRQLEAELSDINHLNKGVLRLGIPPMVG
                     MLMAGPISLFRQRYPGVELKISEFGGLTVQQAVMNGELDVAMTALPVEEASGLTTLSL
                     FSHPLCVLVPRSGQWTTCDSIAPEALAEHPLLIYNEDFALSRQLMTLFSQHDVKPRIA
                     VRSGQWDFLAAMVQAGVGIAILPEPICQRLDKATLRWLPLESDLRWQLGMIWREGVYL
                     SHSARAWLTCCEGFWLKQP"
     gene            complement(29148..30794)
                     /locus_tag="OPV72_000698"
     CDS             complement(29148..30794)
                     /locus_tag="OPV72_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter"
                     /protein_id="HCR9913073.1"
                     /translation="MEIFFTILIMTLVVSLSGVFTRVLPFQLPLPLMQIAIGALLAWP
                     TFGLHVEFDPELFLVLFIPPLLFADGWKTPTREFLEHGREIFGLALALVLVTVVGIGF
                     LIYWLVPGIPLIPAFALAAVLSPTDAVALSGIVGEGRIPKKIMGILQGEALMNDASGL
                     VSLKFAVAVAMGTMVFTVGGATLEFFKVAIGGILAGFVVSWLYGRSLRFLSRWGGDEP
                     ATQIVLLFLLPFASYLIAEHIGVSGILAAVAAGMTITRSGVMRRAPLAMRLRANSTWA
                     MLEFVFNGMVFLLLGLQLPGILESSLAAAEADPNVETWMLFTDIVLIYAALMLVRFGW
                     LWTMKKFSLRFLKKKPMEFASWTSREILIASFAGVRGAITLAGVLSIPLLLPDGSGFP
                     ARYELVFLAAGVILFSLFVGVIMLPLLLQHLEVADHAQQLKEERIARAATAEVAIVAI
                     QKMEERLAADTEENIDNQLLTEVSSRVIGNLRRRADGRNDVESSIQEENLERRFRLAA
                     LRSERAELYHLRATREISNETLQKLLHDLDLMEALLIENQ"
     gene            complement(30944..32293)
                     /gene="ghxP"
                     /locus_tag="OPV72_000699"
                     /gene_synonym="yjcD"
     CDS             complement(30944..32293)
                     /gene="ghxP"
                     /locus_tag="OPV72_000699"
                     /gene_synonym="yjcD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanine/hypoxanthine transporter GhxP"
                     /protein_id="HCR9913074.1"
                     /translation="MSTPSARTGGSLDAWFKISQRGSTVRQEVVAGLTTFLAMVYSVI
                     VVPGMLGKAGFPPAAVFVATCLVAGVGSIVMGLWANLPLAIGCAISLTAFTAFSLVLG
                     QHISVPVALGAVFLMGVLFTIISATGIRSWILRNLPQGVAHGTGIGIGLFLLLIAANG
                     VGLVIKNPLDGLPVALGDFDTFPVIMSLVGLAVILGLEKLKVPGGILLTIIGISIVGL
                     LFDPNVHFSGIFAMPSLSDENGNSLIGSLDIMGALNPVVLPSVLALVMTAVFDATGTI
                     RAVAGQANLLDRDGQIIDGGKALTTDSLSSVFSGLVGAAPAAVYIESAAGTAAGGKTG
                     LTAITVGVLFLLILFLSPLSYLVPVYATAPALMYVGLLMLSNVAKIDFADFVDAMAGL
                     VTAVFIVLTCNIVTGIMIGFATLVVGRLVSGEWRKLNIGTVVIAVALVAFYAGGWAI"
     gene            complement(32640..33308)
                     /locus_tag="OPV72_000700"
     CDS             complement(32640..33308)
                     /locus_tag="OPV72_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase"
                     /protein_id="HCR9913075.1"
                     /translation="MLTVHHLNQSRSQRILWALEELALPYQIVRYQREKTMLAPPALK
                     KVHPLGKSPVIEDHGMVIAESGAILEYLQDTYDNIGRFKPADAQRKQHYRFWLHYAEG
                     SLMPLLLMRLLFTSLGKPPVPLGLRTLGGVIGKGAQKAYLNPQLETHARFIDEHLANH
                     PWFAGEQLSMADIQMSFPLFALLARGGIAHLDHINAWKARVEMRPAWQRAIQQGGPFT
                     IPGG"
     gene            complement(33601..34059)
                     /gene="soxR"
                     /locus_tag="OPV72_000701"
     CDS             complement(33601..34059)
                     /gene="soxR"
                     /locus_tag="OPV72_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensitive transcriptional activator SoxR"
                     /protein_id="HCR9913076.1"
                     /translation="MEKKSPRLKALLTPGEVAKRSGVAVSALHFYESKGLITSIRNSG
                     NQRRYKRDVLRYVAIIKIAQRIGIPLATIGDAFGILPEGHTLSAKEWKQLSSQWREEL
                     DRRIHTLVALRDELDGCIGCGCLSRSDCPLRNPGDRLGEHGTGARLLEDD"
     gene            34146..34469
                     /gene="soxS"
                     /locus_tag="OPV72_000702"
     CDS             34146..34469
                     /gene="soxS"
                     /locus_tag="OPV72_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide response transcriptional regulator
                     SoxS"
                     /protein_id="HCR9913077.1"
                     /translation="MSHQQIIQTLIEWIDEHINQPLNIDVVAKKSGYSKWYLQRMFRT
                     VTHQTLGEYIRQRRLLLAAVELRTTERPIFDIAMDLGYVSQQTFSRVFRREFDRTPSD
                     YRHRL"
     gene            complement(34457..36058)
                     /locus_tag="OPV72_000703"
     CDS             complement(34457..36058)
                     /locus_tag="OPV72_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HCR9913078.1"
                     /translation="MSQSTRRKVLRFLGTIIVVLLPVLLAIWFAHIRAVSETRNQLHS
                     FAQLVLDKTERVILQADLARDAAEQYQGQACTPAHQQRMLNIIRGRLYINELIYAKGQ
                     RFLCSTVMTPTSPYFIPRADYKRKPDIAIYYYRDTPFFNGYKMTYMQRGNYVAVINPL
                     SYSEVMSDDPALAWGMYDTVTNTFFSLSEQAQADQLLPLVQRSEPVFQQGERFYALVK
                     SAKRPVAAIVSTSKQRFYQNLFHQLTLTLPLGIICSIIVLFMWSRSRQAYYSPRRLLQ
                     RAITRHQLCLHYQPIIDIRNGTCVGAEALLRWPGYHGPVMSPCEFIPLAEKEGMIEQI
                     TDYVVEEVFNDLGGFLAAHPHLYVSINLSAADFLSSRLIVMIHEKTRQHSVLAQQIKV
                     EVTERGFIDVPKMTPIIQAFRQAGYEVAIDDFGTGYSNLHNLYSLNVDLLKIDKSFVD
                     TLTTNSASHLIVEHIIEMAQSLRLKIIAEGVETAEQVSWLLKRGVQYCQGWHFAKALP
                     PQEFIVWLQQTPAPLTIRGQTPYRR"
     gene            36621..36902
                     /locus_tag="OPV72_000704"
     CDS             36621..36902
                     /locus_tag="OPV72_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjcB family protein"
                     /protein_id="HCR9913079.1"
                     /translation="MAAITTGVVLLRWQLLSAVLMFLASTLNIRFRKSDYIGLAVISS
                     GLGVVSACWFATGLLGITMMDLAAIWHNIEAVMVETMSQTPPEWPMVLT"
     gene            complement(37181..>38076)
                     /gene="siiF"
                     /locus_tag="OPV72_000705"
     CDS             complement(37181..>38076)
                     /gene="siiF"
                     /locus_tag="OPV72_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="SPI-4 type I secretion system protein SiiF"
                     /protein_id="HCR9913080.1"
                     /translation="IAFFMVIKGDVTTGAIVSSVIVSGRISGIISNFSSTLISILSAE
                     KTGKDLLSFFDEDQAEKTPALQSISKCNGDISIRGVSYQYDAQSPMIINRLSIDIPAG
                     QRVAVIGECGAGKSSLLGMLSGYLSPTDGAILYDGYNLGHLSQNFFSQHLSVVTTHDV
                     LFTGTIESNFALKPQNDRGRVLKALHLANCGFILQHPMGLKFPVNFMAKNLSSGQQQQ
                     LLLARSLSSNASVFLWDEPTSNLDENTEKQIFDNLDEFIHGKTLIMVTHRRYLIKYFD
                     RVLVMKGGKIIRDCSPDKLLM"
BASE COUNT         9374 a        10360 c         9768 g         8574 t
ORIGIN      
        1 tttggcgaga tccggtcttt tatgttcata ttccaggagt tcgggtatga ggatttgcag
       61 caacgagcct tgcatagtgt tattaaccga aaaagataca tggttacgag taaatggtaa
      121 ggagccaatc agtttaaaag cgaatcatat ggccattctg gcttgtgaaa ataacgttat
      181 tgacatttca tcattaaata gcgtgctagt aatacaagtg agtcgcaata atattaaaga
      241 ctatttacaa ttcctgaata aagatctctc acaccttccc gtctggcaac gcaacgccga
      301 tcccttattg accgccacct gtctgacgcc ggatatcttc agggtcgccg cccgctacag
      361 cgcgatggaa acaccggatg aaattgttag tgaacgcacc cgtgcgctcc ttttcaccgt
      421 tttatcccgc tttcttgacc acaaaaaatt tatttctttg ttaatgcaca tgctgcgcag
      481 ccgcatcagt gacagcgttt accacatcat tcagagcgat attcataaag actggaatct
      541 gagcgccgtt gccagctgcc tgtgcctgag tccaagcttg ttaaagaaaa agctcaaaaa
      601 cgagaatacc agttatagcc aaataatcac gacctgccga atgcgttatg ccgtaaacca
      661 attattaatg gacggaaaga atatctcgca agtctcacag ctttgtgggt ataacagcac
      721 gtcgtacttt atttccgtgt ttaaagagtt ttatggtatg acccccctgc attatgttag
      781 ccaacatcgg gaacgatcgg ctgcctaatt tttctacact caacgataag acacgataat
      841 aacagcattg gcgataaccc gtctccgata taattcagcg gcattctgag ggggtatgat
      901 acgacgtaat ttatcgtaac gaagtcacct tttcaggagt ccaaattatg tcttcggatg
      961 ctgatgctca caaagtgggc ctaatccccg tcaccttaat ggtatcgggg aatattatgg
     1021 gttcaggggt attcttactc cctgccaacc tggcggccac tggcgggatt gcaatctacg
     1081 gatggctggt cactatcatc ggcgccctgg cgctgtcgat ggtttatgcc aaaatgtcgt
     1141 ccttagatcc cagtcccggc ggttcttatg cctatgcacg ccgctgcttc gggccgtttt
     1201 tgggctatca aacgaacgtg ctgtactggc tggcatgctg gatcggtaat atcgcgatgg
     1261 tcgttatcgg cgtcggctat ctgagctatt tcttcccgat tctgaaagat ccgctggtat
     1321 taacgcttac ctgcgtcgcg gtgctgtgga tttttgttct gctgaacatc gtcgggccga
     1381 aaatgattac ccgcgtacag gccgtcgcca ccgtactggc gctggtgcct atcgtaggga
     1441 ttgcggtctt cggctggttc tggtttaaag gcgaaaccta tatggcggcc tggaacgtga
     1501 gcggtatgaa taccttcggc gcgattcaaa gcacgttgaa cgtcacgcta tggtcattca
     1561 tcggggtaga aagcgcctcc gttgcggccg gtgtggtaaa aaacccgaaa cgcaacgtgc
     1621 ctatcgccac catcggcggg gtactgatcg ccgccgtctg ctatgtactc tccacaacgg
     1681 cgattatggg gatgatcccc aacgcggcgc tccgtgtgtc agcatcgcct ttcggtgacg
     1741 cggcgcgtat ggcgctgggc gataccgcag gggctattgt ttccttctgt gcggcagcgg
     1801 ggtgcctggg ctctctcggc ggctggacgc tgcttgccgg ccaaaccgca aaagcggcgg
     1861 cggacgatgg tctcttcccg ccgatcttcg cgcgggttaa taaagccggt acgccagtgg
     1921 ctgggttgct tatcgtcggc gtgctgatga ctatcttcca gttcagcagt atgtcgccga
     1981 acgccgcgaa agagtttggt ctggtctcct ccgtgtcggt tatcttcacc ctggtgcctt
     2041 atctttacac ctgtgccgcg ctgttgctat tgggccacgg tcactttggt aaagcgcgcc
     2101 cgctgtatct gctgattacc ttcgtcgcgt ttgtatattg catctgggcg gttatcggtt
     2161 ccggcgccaa agaagtgatg tggtcgttcg tcacgttgat ggtgatcacc gcgctgtatg
     2221 cgttgaacta caaccgcatt cacaaaaacc cgtatccgct ggatgcgccg gttaaacaag
     2281 attgaccacg tgtagttaat gttatcgcaa caggccggat agcgcaggtt atccggccac
     2341 caccaacatt aagttcttaa ggttcactta attttacttt gtcacgatta gcgtcaccga
     2401 atcgatggac gcatcaacat gttaaagcgc tttcttaaaa gacctgttct tgggcaaatc
     2461 gcctggcttc tgcttttttc cttttatatt gccgtctgcc tgaacattgc gttctacaag
     2521 caggtactac aagacctacc gttaaactcg ctgcgcaatg tgctggtgtt tatttccatg
     2581 ccggtcgtcg cgtttagcgt ggtcaatagt gtgctgacgc tggcctcatt tatttggcta
     2641 aaccgactgc tggcctgcat ttttattctg gtcggcgctg ccgcgcagta ttttattttg
     2701 acttacggca tcatcatcga tcgctccatg atcgccaata tgatggatac cacgcccgcg
     2761 gaaacttttg ctctgatgac gccgcaaatg gtgctgacgc tgggattaag cggcgttctg
     2821 gcagccgtga ttgccttctg ggtcaaaatc cgtccggcga cgccgcgctt acggagcggg
     2881 ctttaccgcc tggccagcgt cctgatctct attttattag ttattctggt cgccgccttt
     2941 ttctataaag attacgcctc gctatttcga aataataaac agttgatcaa agcgttaagc
     3001 ccatcgaaca gtattgtcgc cagttggtca tggtattcgc atcaacggct ggcgaatttg
     3061 ccgctggtac gcattggcga ggatgcccat cgcaatccat taatgctgaa aggcgatcgc
     3121 aaaaacctga cgattctcat cgttggcgaa acctcgcgcg gcgatgattt ctctcttggc
     3181 ggctatccgc gcgacaccaa tccgcggctg gcgaaagacg atgtgatcta cttcccgcat
     3241 accacctctt gcggtacggc gaccgcgatc tccgttccct gcatgttttc tgatatgccg
     3301 cgcaaacatt atgacgaaga gctggcgcat caccaggaag ggctactgga tattatccag
     3361 cgcgcgggga ttaacgtact gtggaatgat aatgacggcg gctgtaaagg cgcatgcgat
     3421 cgcgttccgc atcaaaatgt caccgagcta aacctgcccg gacaatgtat cgacggcgag
     3481 tgctacgatg aagtgttatt tcacggtctg gaagactata tcgaccattt gaaaggcgat
     3541 ggcgttattg tactgcatac catcggcagc cacggcccaa cctattacaa ccgttatcca
     3601 ccgcagttta aaaaatttac cccaacctgt gacactaacg aaattcagaa ctgttcccaa
     3661 cagcagttga tcaacaccta tgataatacc gtgctgtacg tggactatat tgtagataaa
     3721 gccattaacc tgctgaaatc tcaccaggat aaattcacca ccagcctggt ctatctttcc
     3781 gatcacggcg aatcattggg tgaaaatggc gtttatttac acggtttgcc gtattccatt
     3841 gcgccggata cgcaaaaaca tgtcccgatg ctcatttggc tttctaaaga ttatcaacag
     3901 cgttatcagg tggatcaggc ctgcctgcaa aaacgggcga gcacgctgga ttattcacag
     3961 gacaatcttt tctcaaccat gctgggatta accggcgtac aaacgacgta ttaccaggcc
     4021 gcagatgata ttctgcaacc gtgcaggaga ctaagcgaat gaagatactg attgttgaag
     4081 acgacacgct attattacag gggttaatac tcgccgcgca aaccgaaggc tatgcgtgtg
     4141 atggcgtttc gacagcgcgt gccgccgagc atagtctgga gtctggtcat tacagtctga
     4201 tggtgctgga tttagggctg cccgatgagg atggcctgca tttcctgacg cgaatccgac
     4261 agaaaaaata caccctgccg gtactcattc tgaccgcccg cgatacgctc aacgaccgca
     4321 ttagcgggct ggatgtcggc gcagatgatt atctggtaaa acccttcgcc ctggaggagc
     4381 tgcacgcccg catccgcgcg ttgctgcgcc gccataataa ccagggtgaa agtgaactga
     4441 cggttggcaa tctgacgctc aatataggcc gccatcaggc atggagggat ggacaggaac
     4501 tgaccctgac gcctaaggag tacgcgctgc tctcacgatt gatgctcaag gcaggcagtc
     4561 cggtgcaccg ggaaattctt tataacgata tctacaactg ggataacgaa ccctcgacca
     4621 acactctgga agtgcatata cataatttgc gcgacaaagt cggcaagtcg cgcattcgca
     4681 cggttcgcag gtttggctac atgctggttg ccactgagga aagctaagtg agcctgatgc
     4741 gttttcagcg aagagcgatg acccttcgcc agcgtttaac gctgacaatt ggtcttattc
     4801 tgctggtgtt ccagctaatc agtaccttct ggttatggca tgaaagcact gagcaaatcc
     4861 aactgttcga gcaggcgctg cgggataatc gcaacaacga tcgccatatc atgcacgaaa
     4921 ttcgcgaggc ggtcgccagc ctgatcgtcc ccagcgtatt tatggttagc ctgacgctgc
     4981 tggtttgcta ccaggcggta cggcgtatta cccgcccact cgccgaactg caaaaagagc
     5041 tggaagcgcg gacggcggat aatctgacgc cgatcgccat tcacagctcc acgcttgaga
     5101 ttgagtccgt cgtctcggcg atcaatcaac tggttacgcg tttgaccacc acgctcgaca
     5161 atgaacgcct ttttaccgcc gatgtggccc atgagctacg cacgccgctg tcgggggtgc
     5221 gtttgcatct ggaattattg tcaaaaaccc acaatgttga tgtcgcgccg cttatcgccc
     5281 gtcttgacca gatgatggat agcgtctccc agcttctgca actggcgcgc gtgggccagt
     5341 cattctcttc cgggaattat caggaagtaa aactgctgga agatgtgatc ctcccctcct
     5401 acgatgagct gaacaccatg ctggaaacgc gccagcaaac tctgttgctg ccggaaagtg
     5461 cggcggacgt ggtggtgcgc ggtgacgcga cgttactgcg tatgctgctg cgaaatctgg
     5521 tggaaaacgc gcatcgctat agccctgaag gaacccatat cactatccac attagcgccg
     5581 accccgacgc tattatggcg gtcgaagacg aggggccggg tattgatgaa agcaaatgcg
     5641 ggaagctaag cgaagcgttc gtgcggatgg acagccgtta tggcggaatt ggcctggggc
     5701 tgagtatcgt cagccgcatc acccagctac atcagggaca gtttttcctg caaaaccgta
     5761 cggaaagaac aggcacccgt gcctgggtgc tgttgaaaaa ggcataacag gcgtttaata
     5821 cgtcgtgacc cacacataga taaaactgct gacaatcagc acactacaca gggtcgtcaa
     5881 acttttataa atatagcttt tcatgacgct ctcctccaaa ggtatggagg agagtatgcc
     5941 cgcgagagat taagcgaacc ttaagcgcga aatttattca tcgatacgcg gatgttgctg
     6001 taccagacgc gaacgtttga cctgcagctc cgcaatttcc tgatcgatgt cgtcgatttt
     6061 ctgctcaata ttatcgtaat gctcgcccag aatttccttc gcttcctgga tgtccgacgc
     6121 cgctggcgtt gcgcctttta acggacgatt ggccgtctct ttcatggaaa taccggtaat
     6181 caagcctatc accgcgatga ccatcaaata atacgccggt atcatcagat cctgcgagct
     6241 ttccaccagc caggccgcca gcgttggcgt cagaccggca atcaatacag agatattaaa
     6301 agccgccgcc agcgcgctgt aacgaatatg cgtcggaaac atcgccggca atgtcgaggc
     6361 catcaccccg gtaaagcagt tcagaatcac cgccagcatc aacaaaccgg caaaaatcag
     6421 gccaataacg ttactgttaa tcaggatgaa ggccgggatc gccagcgcga acagcgcaat
     6481 gctgcccata atcacaaatg gacgtcgacc gaaacggtcg ctcagcagcc ccatcaccgg
     6541 ctgcacaaac agcatcccga tcataatggc gatgataatc aacacgccgt gatcttcaga
     6601 atagtgcagg ttatgcgaca ggtagctcgg catgtaggtg agcagcatgt agtaggtcac
     6661 gttggtggca atcaccagac cgatacatga caacaggcta cgccagtgtt tggtggcaat
     6721 ctctttaaag gagactttcg gcccatcctg caacccttcg cggtcgccct gctccagttt
     6781 atccacgtgc tgctgaaacg ctggcgtctc ctccagcgca tggcgtaagt agagaccaat
     6841 aatccccaat ggcagggcga taaagaacgg aatacgccag ccccactcaa ggaaattctc
     6901 ctcgccgaca atcgtcgaga ttaagaccac cacgcccgcg cccagcacga acccggcgat
     6961 ggaaccaaaa tccagccagc ttcccataaa tccgcgttta cgatccggcg aatattccgc
     7021 gacaaagatc gacgcgccgg tatattcccc gccaaccgag aagccctgcg ccattttaca
     7081 cagcaacaac agtattggcg cccagatacc gatcgtcgcg taagagggga ttaacccgat
     7141 acagaaggta ctgatcgaca taatcacaat cgtgatcgcc aggatcttct ggcgcccgta
     7201 tttatcgccg agcataccaa agaataaccc gccgagcgga cgaatcagga agggaacgga
     7261 aaacgtggcc agcgcggcaa tcatctggac gctgggatcg gcgccgggga aaaagacttt
     7321 acccaacgcg taggcaacaa atccataaac accaaaatca aaccactcca tcgcgttgcc
     7381 cagcgacgcg gcggtaatcg ctttgcgaag tttaccatca tcaatgatgg tcacatcgcc
     7441 cagtgtaatc ggttttattt ttttcctttt cagcatagct gtcctcatag gctaagccct
     7501 gtagcgctat atacggcggg cactggcata ccgcgccagc gtcgccgtcg agcggaggga
     7561 ggggcgcgaa cgctatccct catacaagcg tagcaggttt acttacactg tccggttacg
     7621 gactgtacaa ccgaacctgt tgacgcctga atgggcagtt aatgaccttt ttaccctaac
     7681 agggtttaaa tatgtgatca acttcacaca tatatgtcaa tttggtcaaa aggtgtaaac
     7741 aaggacgccc taatgcgctg tagtggcagt aaaaaagcgg ttattcgagt gtaaaccatt
     7801 gctgactggc gtggcgcagc cccttttata aaagcggcaa tagtcccgac aacactaagg
     7861 attttgtgta taattgcggc ctttttcggc gatctgccat ttttgggcgc gtttgccccc
     7921 gctgactttt tgaggatacc aacatgtcat taccccactg cccgcaatgt aactccgaat
     7981 atacctacga agataacggc atgttcatct gcccggaatg cgctcacgaa tggaacgatg
     8041 cggaacccgc tcaggagagc gatgagctga ttgtcaaaga cgccaacggc aacctgctgg
     8101 cggacggcga tagcgtcacc atcgtgaaag atctgaaagt aaaaggcagc tcttccatgc
     8161 tgaaaatcgg caccaaagtg aagaacattc gtctggttga aggcgaccat aacatcgact
     8221 gcaaaatcga tggttttggc ccgatgaaac tgaaatccga gttcgtgaaa aagaactgat
     8281 ttaccgtatc attgcccggt agcgccttgc ttaccgggcc tgagcggccc tgccaccgac
     8341 aatattgtgc caatttcgaa ctacacttaa cgagcatctc ttacctgagg taaccatcat
     8401 gccgttaagt ccctatctct cttttgccgg caactgtgcc gacgccatcg cgtattatca
     8461 acaaacgtta ggcgcagaac tgctttataa actcagcttc ggtgaaatgc ccccctcggc
     8521 ggcggataat gaagagggct gcccgtcagg aatgcgcttt cccgatactg ctatcgccca
     8581 cgccaacatg cgcattgcgg gcagcgatat catgatgagt gatgccagcg cgtcgggaac
     8641 ggcgcattat tccggcttta cgctggtgct tgatacccag gatgtagcag aagggaagcg
     8701 ctggtttgat aaccttgccg cacaagggca aatcgaaatg gactggcagg agactttctg
     8761 ggcgcagggt ttcggcaagg tcagcgatcg tttcggtgtg ccgtggatga ttaacgtggt
     8821 taaacatcag cctgccacct aactccccgg gaggctcgcc ttcccccttg ccatcagagt
     8881 gatctttggc tgcacgttat ccgccgttta gctgccatag aataaataat gacggtagtt
     8941 tgctacagtc tggcgaaaga tggttgatcc tgatgaagcg tcgggaggac attatgccag
     9001 tctgtgaatt acgccacgcg acaacagagg ataccgattc tgtttacgcg cttatctgtg
     9061 agttacttaa aaatgagctt gattatcagg ctttcaggga tgggttcgcc gctaatttac
     9121 tggaccccaa ccttcattat cgtttagcgc tacgcaacgg agaggtggtc ggcatgatca
     9181 gcctgcatat gcagtttcat ctccatcatg ccaactggat tggcgaaatt caggagctgg
     9241 tggtattacc gcagatgcgg ggacaaaaag ttggcagtca gcttctggcc tgggcagaag
     9301 aagaagcacg tcaggcgggt gcggagctaa cggagctttc cacaaatatt aaacgccgcg
     9361 atgcacaccg tttttatctt cgcgaaggtt acaagcaaag tcatttccgg tttacgaaag
     9421 cattgtgatc tggcaaccgt catcaggaga taaggcataa cgtaatcagc cgtcaccggg
     9481 tgaagtagcg gagtcatctc aattctactg tcgacaagcc tggataaagg ttaaacgggc
     9541 tgactcgctt ctttaacaaa aatggccctt ttaagttgta gaaatgtaaa tttattgtca
     9601 acgaactaca cttttctctt tggcatcacc gggagggttg cctgaaaatc ccgggatgag
     9661 gttttcttag aaggacagtg acgttatgtt cgcagcaatc attatcggta tttttattat
     9721 cagcgtcatt tatgcgcatt cacgcggggt ggaaaaacaa aaactttccc gtcagctctt
     9781 tgaccactcg acgtttatgg cgccgatcaa tatgttcatg actcgcttct caacgttacc
     9841 ggcaaagcag ccgtactttg ataccacggc atttccagag ctgcagaagc tgacggaaaa
     9901 ctggcaggtg attcgtgaag aggcgctacg gcttcagcat cacataaaag ccgcgcaggc
     9961 caataacgac gccggattca acaccttttt caagcgcggc tggaaacggt tttatcttaa
    10021 atggtattcc gatgcccacc cgtcggcaga aacgttatgc ccgataacga caaagctggt
    10081 caacagcatc ccctctatca aagcggcgat gttcgccgag ttgcctcccg gggcctatct
    10141 gggaaaacat cgcgacccct atgccggttc agtacgttac catcttggat taagcacacc
    10201 gaatgatgac cgctgtttta ttgaagttga tcgacagcgc catagctggc gcgacggcga
    10261 agccgtcatc ttcgacgaaa cctacgttca ttgggcggaa aataaaactg agcagacgcg
    10321 tattatcctc ttttgcgata ttgagcgccc aatgaaatgg cgctgggcgc agagcgtaaa
    10381 ccactgggtc ggcgcatcgt tgatgtccgc cgccagttcg ccaaacgacg agaacgatcg
    10441 caccggtgcg attaatcgca tctttaaata cgttcacgca gcacgcgatg ccgggcaacg
    10501 gctgaaaaag aaaaaccgta ctctctatta cgcgctgaaa tatctcgtta ttgccgctat
    10561 ttttgccgcg ataatccttt tcagcctcct ctgaagccgg gccacggtat gaaactgcct
    10621 gccgcggcct gttctatcct ggcgttagtc tcaaagcgtt ccctgacctt gagtctatcc
    10681 atccggataa tatccacttc aggcagagcg ttccgcctta tctggcctgc gctccgcgtt
    10741 tctccccata ataaatgtca tgcggcattt tctttcgaca cgtcaaaact gacgatagcc
    10801 tgtttttcgt cagggttttg agcaaaattc gcccgtaata tcagggaaag cccatactaa
    10861 aaaagtggca taaaacatgc atactgaggg cgacagcgcg tatgcgcgat ttgattaact
    10921 ggagcgaaac cgatgaaaaa agtcgtcacg gtttgcccgt attgcgcatc aggttgcaaa
    10981 atcaatctgg tggtcgataa cggcaaaatc gtccgggctg aggcggcgca ggggaaaacc
    11041 aaccagggta ccctgtgtct gaagggctac tatggctggg attttattaa tgatacccag
    11101 atcctgaccc cgcgtctgaa aaccccaatg atccgtcgcc agcgtggcgg caaactggaa
    11161 tctgtttcct gggatgaagc gctcaattac gtcgctgaac gtttgagcgc catcaaagcg
    11221 aagtacggtc cggatgcaat ccagacaacc ggctcctctc gcggtaccgg aaatgaaacc
    11281 aactatgtaa tgcaaaaatt cgcacgcgcc gttattggta ccaataacgt tgactgctgc
    11341 gctcgcgtct gacacggccc atcggttgca ggtctgcacc aatcggtcgg taacggcgca
    11401 atgagtaatg cgattaacga aattgataac actgatttag tgttcgtctt cgggtataac
    11461 ccggcggatt cccaccctat cgtggcgaat catgtgatta acgctaaacg caacggggcg
    11521 aaaattatcg tctgcgatcc gcgcaaaatt gaaactgcgc gcatcgctga catgcatatc
    11581 gcgttgaaaa acggctcgaa tatcgcgctg ctcaacgcca tgggacatgt cattattgaa
    11641 gaaaacctgt acgacaaagc gtttgtcgcc agccgtaccg aaggttttga agagtacagt
    11701 aagattgtcg aaggctatac gccggagtcc gttgaagaga tcactggcgt gagcgcacag
    11761 gagattcgtc aggcggcgcg gatgtatgcc agcgcgaaaa gcgcggcgat cttgtggggt
    11821 atgggcgtca cccagttcta tcagggtgtg gaaaccgtgc gttcactgac cagcctcgcg
    11881 atgctgaccg gtaacctcgg caagccaagc gcgggcgtta acccggttcg cggccagaac
    11941 aacgttcagg gcgcgtgcga tatgggcgcg ctgccggata cttatccggg ctaccagtac
    12001 gttaaattcc cggaaaaccg cgagaagttc gctaaagcct ggggcgtaga aagtctgcct
    12061 gcacataccg gctatcgcat cagcgagctg ccgcaccgtg cggcgcatgg cgaagtgcgc
    12121 gcggcgtaca ttatgggtga agatccgctg caaaccgatg cggagctctc tgcggtacgt
    12181 aaagcgtttg aggacctgga actggtcatc gtgcagggca tcttcatgac caaaaccgcg
    12241 tcggcggcgg atgtgatttt accctccacc tcctggggcg agcatgaagg cgtcttctct
    12301 gcggctgacc gtggcttcca gcgcttcttt aaagccgttg agccgaagtg ggacctgaaa
    12361 accgactggc agattatcag tgaaatcgcc acccggatgg gctatccgat gcactacaac
    12421 aacacccagg agatctggga tgagttgcgt catctgtgcc cggatttcta cggcgccact
    12481 tacgagaaaa tgggcgaact gggctatatc cagtggccat gccgcgacac gtcggatgcc
    12541 gatcagggaa cctcgtacct ctttaaagag aagttcgata cccccaacgg tctggcgcag
    12601 ttcttcacct gcgactgggt agcgcctatc gataaactca ccgaagagta cccgatggta
    12661 ctgtcgacgg tgcgcgaagt cggccactac tcctgccgct caatgaccgg taactgtgcg
    12721 gcgctggccg cgctggccga tgaaccgggc tatgcgcaaa tcaataccgc cgacgccgcg
    12781 cgtctgggca ttgaagatga agcgctggtg tgggttcatt cgcgtaaagg caaaatcatc
    12841 acccgcgcgc aggtcagcga tcgcccgaac aaaggggcga tttacatgac ctaccagtgg
    12901 tggattggcg cctgtaacga gctggtgact gaaaacctca gctcgattac caaaacgccg
    12961 gagtacaaat actgcgccgt acgcgttgag ccgatcgccg atcagcgagc cgccgagcag
    13021 tatgtgattg atgagtacaa caagctgaaa acccgcctgc gcgaaagcgc aatgggttga
    13081 tctgccggat ggcggcatca gaatgcttta ttcggcctgc gtctactgta ggcctgataa
    13141 tatgcattag catcgccatc aggcattttc cctataacag cctccgcccg gaggctgttt
    13201 ttttatccat acgatctctt tatactgtct tttccgtacc ctaaataaaa ttcaaaatga
    13261 aaccacttat tgcattgatg ttgtttatga cattctttgc ccatgccgca gatcctgagc
    13321 cgggtagcca gtatttgcag gcagcagagg caggtgacag acgcgcgcaa tattttctgg
    13381 ccgacagttg gttgagctat ggcgatttga acaaagctga atactgggcg caaaaagccg
    13441 ccgacaatgg cgacgccgac gcctgcgcgc tactggcgca aatcaaaatc actaatccgg
    13501 taagcctgga ttatcccgac gcgaaaaagc tggctgaaaa ggcggctaac gcgggcagta
    13561 aagcgggaga aattacgctg gcgcggatcc tggtcaacac ccaggccggg cgtccggact
    13621 acccaaaagc catctcgctg ctgcaaaagg cctctgaaga tctggataac gactccgcgg
    13681 tggatgcgca aatgttgctt ggcctgattt acgccaacgg cgtgggcatt gccgccgatg
    13741 atgaaaaagc cgcctggtat ttcaaacgca gttccgctat ttcccgtacc ggctattcag
    13801 aatactgggc gggaatgatg tttttaaacg gtgaaccggg ctttattgaa aagaacaagc
    13861 agaaggcgtt gcattggttg aatctaagct gtctggaagg gtttgatacc ggttgcgaag
    13921 agttcgaaac gctaacaaat ggctgatgtt tattgcctga tgaacgtagt cgttgtaggc
    13981 ctgataagcg tagcgccatc aggcaacccg gagccggttg tcggatggcg gcgtgaacgc
    14041 cttatccggc ctacattctc tttctctgta ggccggataa gcaaagcgcc atccggcaat
    14101 ccgttattgg gcggtcttat caaatttgcc cagtacgtcg cgctcatagg ccagcgcttt
    14161 tttacggtca aacttgtgtt cccacttggc gataaccagc accgccagcg cattccccac
    14221 cacatttagc gcagtacgcg ccatgtcgag gatacggtcg acaccggcga taaacgccag
    14281 cccttccagc ggaatgccca cgctgcccag cgtcgccagt aacaccacga aggaaacgcc
    14341 aggcacgccg gcaatccctt tcgacgtcac catcagcgtc agcaccagta caatttcctg
    14401 ccacagcgac aggtcgatac cgtatagctg cgcgataaaa atggcggcga tgctctggta
    14461 taacgtggag ccgtcgaggt taaatgagta accggtcggc accacgaaac tggtgataga
    14521 ggctggcgcg ccgtaagctt ccatcttctc gataatgcgc ggtagcacgc tctcggagct
    14581 ggcggtcgag tacgccagaa tcaattcatc tttcagaatg cgaatcagaa tccagatact
    14641 taacccgcac aggcgcgcca cgatgcccag caccaccagc gcaaagaaga taatggcaaa
    14701 gtgtaccagc agcaccagtt tcgccagcgg ccacagcgac gcgaaaccaa aattcgctac
    14761 cgtgacggcg atcagcacaa aaacgcccac tggcgcatag cgcatcacca tatgggtgac
    14821 tttaaacatg gtttcagaga tggaacgaaa taccgtcacc agcggttcgc ggtgcgttgc
    14881 cggcagggat gacaacccca gcccaaacag gaccgagaaa aagataattg gcagcatatc
    14941 ccctttggcc atcgatgcga tgatattggt cggcaccagc gacagtatcg tccccatcag
    15001 cccatgtgca tgactttgta cttccgccgt ggtgttctgg tatttcgaaa tatcgacggt
    15061 cgccagttgc gacatatcaa tgcctgagcc tggctgaaag acattcgcca gcgtaatgcc
    15121 gaggataatc gccaccgtgg tgatcagttc aaaatagaga atggttttgg cgccgatacg
    15181 gcctagctgt tttgcatcgc caacgccggc gatgccgaca atcagagtcg agatcacgat
    15241 tggcacgacg atcattttaa tcagatggat aaagatatcg ccagcaggcg acagcagatt
    15301 ggcaatcagc cattcacggc tgtcactgtg ataatgcaga tagctgccca gcagaatgcc
    15361 cagcaccata gccagcaaaa tttgccaggc caggctgact ttcaaatttt tcataacaac
    15421 agacttcctc gatgaagcgt tgctctccgc cgaaagcatg agagcaatac atactggaag
    15481 ggtatgattt gtgttgcgtt ggtttgtaga gttttttaac gcgcataatc agtatcattt
    15541 gcatagcgtc ttgcgcaacc ctttcataac agggcttttg gctgttttta tgcataataa
    15601 cgcgagttta tggtgttaat gatgaataac tatttgttat gcaaagtttt ttacttcgtc
    15661 aaaatcgaat aatattctga ggtaattaat ttttacctgt ggcgcattcg ccgttttttt
    15721 aaacagcaca catgacaaaa gtcacaaaaa agaaaaaatt atttctgccg attttgtaac
    15781 aatttagcca aattaatggc ctctaccagc tgcgcgcggt tcactcgcgg cgagtttgca
    15841 tccagtaagg tttgccacag cgacacggct tgcgcataat ccgcctgcat aaacgcatcc
    15901 gccgccagca gcatctgcgc ggtcacttct gtcgcatcca gcgctaacgc tttattaatc
    15961 atttcacgcg tcgcaggcgt catatgttgc ccggactggt aatacagcac cgttgccagc
    16021 gcggcgaaaa gctgcgcgtt atcgcctcgc agacgcaacg cctgacgata tgccagcagc
    16081 gcattgtcat acgcattgcg atagagataa tactcgccca gccgcgccca ttgctcgcta
    16141 tcctgcggat tggcgcggat tttttcttgc agcctggaaa gctgcgcctc tggcgtttgc
    16201 gggttcgtaa agtcacgtag cggatcggcc agacgctgtt gctcgctacg cacagcctgc
    16261 catttcggcg tcaacatata gccgccgata cagacagcca ccatcaacac cgccgcagcc
    16321 gtcagacgct ttacgggcat gggacgtaac ggcacagtgg agtgctcaga ctggctcatt
    16381 gttccccctc ttctgcgtgc tgacgctttc tcacccgcca gaccaccacg cccaccaaca
    16441 ataacagcag gcacggcagc gcccacaaca gcagcgtttg ctcattcaac ggcgggttgt
    16501 agcgcacgaa atcaccataa cggtcggtca tccaggcggt gatttccgct tcgcttttac
    16561 cttcggccac catgctgtaa acctgatggc gcatactgac cgccacgggc gcattggatt
    16621 ccagcaaatt ctggttctga cactgcggac agcgcagttg accggcaata gacagcgctt
    16681 tttcctgctg ttgtggattg tcaaagcgcc aggtatccac cacctgggcg tgggtggcga
    16741 atgtgattaa aaacaggacg atcgttaaga gtaaaaactt tctgccggat ggcgctacgc
    16801 taatccggcc tacggtttgc gcatcctgta ggccggataa ggcgcttacg ccgccatccg
    16861 gcaacgctgt gagtaattta cgcatcacgc ttcctccccc gccatccgct cagcagcgcg
    16921 ccacacacca tcaacaatcc ccctccccag atccagcgca cgccggtctg cacgtataag
    16981 cgcatggcgt aacggtccgc tccggttttt tcgcccatca ccgcgtacca gtcatgtagc
    17041 aggttccagt gaatccccgg ctccatcatc tgttgacgac gcgcggcata gaagcgcctt
    17101 tcaggctgca ggctgccaat gcgtttttca ttccgccaca acgtgatccg cgctttttca
    17161 ctggtgtagt tgcctttggc ttccagatcc agacgctcga aacgaaaggt atagcccgcc
    17221 agtaccacct gctgccccgg gctgaggtta aggctgattt catgccgact gccgctggaa
    17281 accatgatcc cggcggcgaa gataaatacg cccgtatgcg ccagcaacgc cggaagctga
    17341 cgatgcacag agactttgcg gcttctgatt gtcgcaagca cgataaccac cagcatcagc
    17401 aggccaaacg gcagcgtgac gcgattaaaa tagggcgcgc ccaccgaaag ccttccccag
    17461 cccatcaaac cataaatcat ggggtagagc gtcccgacca gcacgatcaa caagacggcg
    17521 ctaaagagca gcagcgtcgc cagaatgagc gtttcgcact ttccgccgcc caaacgcgtc
    17581 gccggatacg gctcccgtgc ccgccagccg tacagagcaa gcgatgccag acttaacgcg
    17641 gcaaaaagga taaacagcgg caccgcgcgc acattatcta acgcaaaagc atggacggag
    17701 agcagaatgc cggaacgcac aatcagcgtt cccagcaacg agaggatcag cgtcagtatc
    17761 gccagcagca acgaccagtg gcggaagctc ccgcgctggc ggctgacata cagactgtgc
    17821 agcaacgcgc tggcggcaag ccacggcaac aatgaggcat tttccaccgg gtcccagaac
    17881 caccagccgc cccagcccag ttcgcaatac gcccaccacg atccgagaat gatccccagc
    17941 gtcagagcgc accagccgag taacgcccag cgccagcaca cccaggcggt tgccgcgtta
    18001 aagccgccgc acagtagcga ggccagcgct acgctcgccg cggtcatcag gccgccataa
    18061 cccagataga gcagcggcgg atgtaagatc agccccagat gttgcagcat gggattaagg
    18121 tcgcgccctt ccatggcggg agggaaaata cgcaggaacg gatcggacca cagcacaata
    18181 aatagcagca gcgaagccat aatgagggac aagatgctca gggtcagcgg aaaaagcgcg
    18241 tcagattcat gccgggagcg ccaggcgaat agcaccgtcc accccgaaag aagcagcgcc
    18301 cacagcagga gcgagccttc atgaccgccc cataccgccg ccagtttcag tccccatgac
    18361 aactgactat ggctatgctg cgcaacataa acgaccgaaa aatcgctggt cagaaaacag
    18421 ctaaacagaa tcgcaaacgc cagtagcagc agcgtgaacg ccgtccacgc gccgcaggtc
    18481 gtcaggcgca tgacgccacg ccaatgctgc gccatcccgc accacgtcgc cagcggggtt
    18541 aacacgttga ccccgagact caacaacagc gccagaaatc cggcttcagg aaggaagatg
    18601 tccagattat gcaaccgtta gctgtcccgc ataaagaatg aaaaagcgca gcagcagcac
    18661 gccggtcaaa ctggcgccgc aaacggccag cacgccgtga aacgtgacgc tgcggttggc
    18721 ccagggtttt agcagcatcg ggataatcaa tcccagccct acgacgccaa gccagaacca
    18781 ccagctccag aatccgccgc ccagcgccgc cgccagcgcc cgcattttgc cgtcatcgcc
    18841 cagcgccaga ccgacgaaga acgccgccag caggaaaatt tccagccata ccaccggaac
    18901 ctccatgcga tgcacaaagc gcgcttccgt gctgtgcggg ttgctacgat ggcgtaacgc
    18961 catggcgatc agcgccaccg ccgcgccgga ggaaatcccg gagaacagga atagtaccgg
    19021 caggatcggg ttattcagga acggatagga tttcagcgcc gacagcagaa agccggtgta
    19081 cgcgccgagc agaaccgcca gcaccagcat taacgtctcc agcgcacggt ggaacggcgc
    19141 gatcagcgtc aacactttct gcacgatctc taaccgcggc agccaacgtt gctgcagggc
    19201 aatcacctct ttttcaaaga ttttcgccag ccacagtatc aggaccacca tgtaaagctg
    19261 gaacagcatc acccccatcg acatcaccga ggtaaagctg tagtgaaaca tcagcttcca
    19321 gaaggtccac gggcgcgtca ggtggaagac cagaatcagc agaccaagaa taatcgcccc
    19381 cggccctaac accagcgtag tgcgcagcag cgtgctgtcc gaaccgcccg cctccggatg
    19441 gaagcggcgt agcagaatcg ccaacgtaac cagtccggcg gagatgccaa tcaggaacag
    19501 atagatggcg atgggccagt cccacaccag tgatgcaaaa tgaaatgcag aagcggatgt
    19561 cattggctca cctccccata gttaaaggga acgcggtaga ccttcggttt tgtgcccagc
    19621 gccagcttgt aacgataggt ggttttctgc cgcaacaaac gggagatatc gctgttggga
    19681 tcgtccagat taccaaacgt cagcgccttc gttagacatg actcaacgca ggcgggctgt
    19741 ttgcccgctt tcaggttagt tttccggcag aaatcgcact tatccgccgt cttactgacc
    19801 ggatggataa agcgcacgcg gtagggacac gcggcaatgc agtactgaca gccgacgcaa
    19861 aggtccgggt tcacgtcgac aataccactg gcggcatcgc ggaatgatgc gccggtcggg
    19921 cagacgtcaa cgcagggggc atggtcgcaa tgctggcacg agtggcggaa gaagcgatat
    19981 ttcacatcag gaaacgtccc ctgcggctcg ctgcgaataa tcgtcaggcg cgatacgcct
    20041 tccggcacgt tgttgacttc ccgacaggca tccatgcagg ccgtgcagcc gatgcataat
    20101 gactcatcgt gtaccatgcc ataacgcacg ccgttaatat tcaacgtgtt cgctacaacg
    20161 cgtcctgcca tcccactgac cgccgccagc gcgccgacgc gggtaataaa ttgacgtcgg
    20221 gtgcaactca tggctgctcc ttaagcaacg gaacggacgc cgggttaaag tgcgggttag
    20281 tacgctgatc gctgtggcaa tccacgcata ttttgatccg ccctttctcg tttagcgtct
    20341 gcatcgtgtc ttgctgcgga tgcagggaat ggcaactggc gcaggtcact ttagtaacat
    20401 gaacatcgtg cggccagaac gctttttgca gttgttcagg caagtggcag gacatacaga
    20461 cgctgttctg ctgctctacc gtatacatcg ggtcgttaaa acgcatcaca tctttcaccc
    20521 cttcacggtg gtgaagcgac ggttgaccgt ggcagttggt acaggttatc ggcaatttat
    20581 tgttcgggtt gatagcgccc gtatgtttac cgtgcatacc ttcggtgtcc ggcttgtgac
    20641 agtccagaca ggcagcatcc ggattacgct gctgggtgac cgtccagcgt tgatccgact
    20701 cctgcggcgt tggcgtggca gtaattccac tcaggctcca gaacaggcct gatgccagca
    20761 ccccagcagt taataacgaa cgtaatacgc tcatattcac tccattacat aatgcctgat
    20821 ggcgcgcagc tttaaggcct acaagacttc tgtaggccgg ataaagcgct tgcgctgtca
    20881 tccggcaaat ttgtcacatg tgaggttatt ggcttaacag accgttttta cgcgcctgat
    20941 cttcccactg cggtacgacc gttttcagga agtcctgctt ctccgcgttg atttgttgca
    21001 tattcaaacc aatcgctttc tgcgccttct ctttcgtcga aatatccggc agcggaattt
    21061 catgggtaat gcctttggtc gccagcagtc gcgccagttt agttcgggca tccgcggctt
    21121 tatccatcgc actgcctaac atccgtagac cttcttccgg ggcatgcata tgaataccgt
    21181 gtgacgcaat cgccagatcc caacgccact gcgcgtggcg aatatcgttc agaatcggtt
    21241 tcatttccgc gtctgtcgcc cccgcatccc atgcggcttt cgcttcgaag tgcgcatgta
    21301 ccagctgatc ttcaaccttg attttcaggt catgaatcgc ctgtttacgc tcggcgacca
    21361 ctttttgcag ggacgctttg tcctgggtgt ggcagttggc gcaggtttgc gcgaaattgt
    21421 cgaacgggtt gccgatttta tggtcggtgt agagcttgcc ttcggcgttc tgtactttcg
    21481 gcatgtggca gtcgatacag gtcacgttgt tcttaccgtg aatgcccgcg ctccaggttt
    21541 catattccgg gtgctgcgct ttgagcattg gggttttcga cagcgagtta gtccagtcag
    21601 agaaggcgat ggcgtcgtag tattgctcca tattttcgac cttcatgccc tcatcccacg
    21661 ggaacttaac ggctttgttc ttaccgtcga agtagtactc cacgtggcac tggccgcaga
    21721 ccatcgattg ctgatcaaat cgtcccgctt tatcaaacgg tttgccgata gcctccatcg
    21781 cccgttcggc ataggggcgc gacaacgtta tcgctggctt cccctgggcg aaatcgtccg
    21841 acgcggtgtt atgacagtcg gcacagccca aatcgttgac aatttccggg ccgccgcgcg
    21901 cccatttgcc atggaagtag ccgtcttcgc cttcttgttg gataaggcgc gcgacatcgg
    21961 ggcttttaca gctccagcag gccatcggca gcgggccgtc ttccgccgtt tttggcgcgc
    22021 cggtacgcag cgtttcgcgc acgtcggtta ccgcatacgc gtggccgcgt ggtttgttgt
    22081 aatcacggga gaagggatag cccgcccaca ggatcaccag acgagggtct tccgccagcg
    22141 catcttcacg ggcagactgt tctgacgtcg ctttccatga ctgatattgg tcggggtgtt
    22201 gaggcgcgaa cgtttcattt ttcgcttcaa cagtaacggt ttttgcggat acaggcgttt
    22261 gctcagcgta aacagaggta atgaagaaaa aaggaaatat aaggctgaag aaacggcgtg
    22321 cgcgtagtgt tttccttgcc atagaggtct catccagatt gcgccattat ctttaatggc
    22381 gattttttat cgttttccat aacagcaacc gcacaaatac tgttattaca ttgatctcct
    22441 ctatgtgtaa caaataacca cactcaaaat gttgtcttta atcaattgta agtgtatgta
    22501 aaataccact ttagagttag taacctggac aaaactccct ctcttttctg atttccggac
    22561 acggatcact tttttaaaaa atttcatata acgtcatgtt atcccgaaaa tttatctaat
    22621 tttgcgggac acaatcaaaa aatagattgc tgcttatttg cacagctccc tttttgcgtg
    22681 atctgtcgcc caaatactaa acaaaactta ttaagaccct acatttaacg tttatgcgac
    22741 atattattaa catcctacaa ggagaacaac agcatgagcc aaacacataa acacgccatt
    22801 cccgccaaca ttgcggatcg ttgcctgata aatccagagc agtatgagac taaatataaa
    22861 cagtctatta acgaccccga tacgttttgg ggcgaacagg gaaaaattct cgattggatc
    22921 acgccgtacc aaaaagtgaa aaacacctcc tttgcgccag gcaatgtgtc gattaaatgg
    22981 tacgaggacg gcacgctgaa tctggcggcg aactgtcttg accgccattt gcaggaaaat
    23041 ggcgatcgca ccgccattat ctgggaaggc gatgacgcgt cgcagagtaa acatatctct
    23101 tatcgcgaac tgcatcgcga tgtctgccgt ttcgcgaata cactgctgga tctgggcatt
    23161 aaaaaaggcg atgtggtagc gatttatatg ccgatggtgc cggaagcggc ggtggcaatg
    23221 ttggcctgcg cccgcatcgg tgcggtgcat tcggtgatct tcgggggctt ctcgccggaa
    23281 gccatcgccg gacgcattat cgactccagc tcgcggctgg tgatcaccgc tgacgaaggt
    23341 gtacgtgccg gacgcagtat cccgctgaaa aagaatgtcg atgacgcgct gaaaaacccg
    23401 aatgtcacta gcgttgagca tgtgatcgtc ctgaagcgca ccggcaacga cattgactgg
    23461 caagaaggcc gcgacctgtg gtggcgcgat ttgattgaaa aagccagccc tgagcaccag
    23521 cctgaagcga tgaatgccga agatccgctg tttatccttt atacctccgg ctccaccggc
    23581 aagccgaaag gcgtgctgca caccaccggc ggctatctgg tctacgccgc gaccaccttt
    23641 aagtatgtct ttgattatca ccctggcgat atttactggt gtaccgccga tgtgggttgg
    23701 gtgacggggc acagctatct gttgtatggc ccgctggcct gcggcgcgac caccttaatg
    23761 tttgaaggcg tgccgaattg gccaacgccc gctcgcatgt gccaggtggt cgacaaacac
    23821 caggtcaaca ttctctatac cgccccgacg gccatccgcg cgctgatggc ggaaggcgat
    23881 aaagccattg aaggcaccga ccgttcttca ctacgcattc tgggttccgt cggcgagccg
    23941 atcaatcccg aagcgtggga atggtactgg aagaagatcg gcaaggaaaa atgtccggtc
    24001 gtcgacacct ggtggcagac tgaaacaggc ggttttatga tcacgccgct accaggcgct
    24061 atcgaactga aagccggttc cgccacccgt cctttctttg gcgtacagcc tgcgctggtg
    24121 gataacgaag gccatccgca agaaggcgcg acggaaggca atctggtcat caccgattcc
    24181 tggccgggcc aggcgcgcac tctgttcggc gatcatgaac gttttgagca gacctatttc
    24241 tctaccttta agaatatgta tttcagcggc gacggcgcgc gtcgcgatga ggacggctat
    24301 tactggatca ccggtcgcgt ggatgacgtg ttaaacgtct ccggccaccg tctgggtacg
    24361 gcggaaatcg agtcagcgct ggtggcgcat ccgaagatcg ccgaagcggc ggtggtgggt
    24421 attccacacg ctatcaaagg ccaggcgatt tacgcttatg tgacgctcaa ccacggcgag
    24481 gagccgtcgc cagaactgta cgcggaggtg cgcaactggg tacgtaaaga gattggccca
    24541 ctggcgacgc cggacgtgct gcactggacc gactcactgc caaaaacccg ttccggcaaa
    24601 attatgcgcc gcattttgcg caaaatcgcg gcgggcgata ccagcaatct gggcgatacc
    24661 tcgactctcg ccgatcctgg cgtggtggag aaactgctcg aagagaagca ggccatcgcg
    24721 atgccgtcat aaccataaat gccggatggc aacgcgaacg cgttttatcc ggcctacgac
    24781 cctacccctg ccctctctca aaccgggaga gggaaatata aaaaccctcc cccaaaggat
    24841 ttcgtgttac aggaaggcgg caagcgagca caccctcagc agcatagttc actatgtggc
    24901 tggggcgcgc gagtgcggcc agcgcgcctg tagcgcgaaa gacgcagggg gacctctgga
    24961 gagctctgtg atgaatgacc aaatttatca gcggatagaa gacagtgcgc gtttcaggga
    25021 attagttgaa aaacggcaac ggtttgccac gattctgtcg gttatcatgc tggcggttta
    25081 tatcagcttt attttactga tcgccttcgc gcctggctgg ctgggcacgc ctctacatgc
    25141 gggaaccagc gtcacccgag gaattcccat tggcgtcggg gtgattgtga tttcttttgt
    25201 gttgaccgga atttatatct ggcgggcgaa tggcgaattc gatcgtctta ataacgccgt
    25261 actgcatgag gtgaaagcat tatgaagaga gttctgacgg cgctcgccgc cgcactcccc
    25321 ttcgccgctc atgcggcgga tgccattagc ggcgcggttg aacgccagcc caccaactgg
    25381 caggcgatta tcatgttttt gattttcgtc gtgtttacgc tcggtattac ctactgggcc
    25441 tctaaacgcg tacgttcccg tagcgactac tacacggctg gcggcaatat caccgggttc
    25501 cagaacgggc tggcgattgc cggcgactat atgtccgccg cgtcatttct cggcatttcc
    25561 gcgctggtgt ttacctccgg ttatgacggg ctgatctatt cgctgggctt ccttgtcggc
    25621 tggccaatta tcctgttttt gattgccgag cgcctgcgta atctgggacg ttatactttt
    25681 gctgacgttg cctcttatcg cctgaaacag gggccaatcc gtattctttc ggcctgtggc
    25741 tccctggtag tggtggcgct ttatctcatc gcccaaatgg tcggcgccgg taaactgatt
    25801 gaactgctgt tcggcctcaa ctatcacatc gccgtagtgc tggtcggcgt gctgatgatg
    25861 atgtacgtgc tgttcggcgg gatgctggcg acaacgtggg tgcaaattat caaagccgtc
    25921 ctgttgctgt ttggcgccag ttttatggcc tttatggtga tgaaacacgt cggctttagc
    25981 ttcaataatc tgtttaccga agccatggcg gtacacccga aaggcacggc gattatgagc
    26041 ccaggaggat tggtgcaaga tccgatttcg gcattgtcgt tgggtctggg actgatattc
    26101 ggcaccgccg gtttgccgca tattctgatg cgtttcttta cggtcagcga tgcccgcgaa
    26161 gcgcgcaaga gcgtgttcta cgccaccggt tttatgggct atttctacat tctgaccttt
    26221 attatcggct tcggcgctat catgctggtg ggggcgaatc ccgcctataa agatgccgca
    26281 ggcgcgctga ttggcggcaa taacatggcg gcggtgcatc tggccaacgc ggtaggcggc
    26341 aacctgttcc tcggctttat ttcggcagtg gcgtttgcca ccattctggc ggtggtcgca
    26401 ggtctgacgc tggcgggcgc atcggcggtg tcgcatgact tgtacgccaa cgtgttccgc
    26461 aaaggcgcaa ccgaacgtga agagctgaag gtgtcgaaaa tcaccgtcct ggtgctggac
    26521 gtgatcgcca ttatcctcgg cgtcctgttt gaaaatcaga acatcgcctt tatggtgggc
    26581 ctggcatttg ctatcgccgc gagctgcaac ttccccatca ttctgctttc catgtactgg
    26641 tcaaaactga ccacgcgcgg cgctatgctg ggcggctggt taggtttact gacagcggtg
    26701 gtgctgatga ttcttggccc taccatttgg gtgcagatcc tcggccacga aaaagcgatc
    26761 ttcccgtatg agtatccggc gctgttctct atcagcgtgg cgttcctggg gatctggttc
    26821 ttctcggcca ccgataactc ggcagaaggc aaccgtgaac gtgagcagtt ccgcgctcag
    26881 tttatccgct cccaaacggg attcggcgta caacaagggc gtgcgcatta atcttaccgt
    26941 ttcctccggc cctgtgggtc ggaggaaaat cagaacatca ccctcgccac cagcggggct
    27001 gccagcacca tcaccacgcc ggacagcatc attaccagac tggcgacgac gccctcctgc
    27061 tgaccaagtt cataggaacg cgccgtgcct gccccatgtg acgccgcgcc gaatcctgcc
    27121 ccttttgcca tgccttcccg gatagagaga cgcaaaaata gcgcgtcgcc gaccgccatg
    27181 ccaaacacgc cagtgacgac cacgaacagc gccaccagat ccggctgccc gcccaggggt
    27241 tctgccgccg ccagcgcaaa cggcgtagta acggaacgta ccgccagact acgctgaatc
    27301 tcatccgata acgtgaacag acgcgccagc caaacggaac tggtgaccgc caccaccgtc
    27361 gccgtcacta cacccgcggt gagcgacatc cagtgacgtt tgataatcgc gaggttatcg
    27421 tacaccggca ccgcaaaggc aatggtcgcc gggccgagca gccacaatag ccagtgcgat
    27481 tcgctaatat agttttgcca ggagatatga ccgaacacca gcattaacac cagcagtgcc
    27541 ggcgtcaaca ctaatggcat caacggcaat ttgcgaaaac ggcgatacag acgcttattg
    27601 gcgaagtaaa ttcccagcgt aatcactagg cacagtacgc ttaactgaac gttattcacg
    27661 gtttagcctg ctcatctcat agcgatacac tttatccacc acccacgccg tcgcgccgag
    27721 taccattaag gtactgatcg ctatcaccga gaaaatgcgc cagccgtcca ccagtaacag
    27781 atgggcatag ttcactaccg ccacgacggc gggaacaaag aataacagca tctccgccag
    27841 cagccagcgt gcgcctgcgc gtacccagct aagcggaata atccggcaaa cgatcagcgc
    27901 caacataagt accatgccga ccagattcgc gggcaacggc aggtgcagcc aggagacaag
    27961 atattgggaa aaaatgaata aacctgcata gagcagtacc tgaaccggta cctggagtcg
    28021 ttgcacaacg gcaggcgtaa cgcggcttat cgccacagcc atgagggaat gtcctgaaaa
    28081 ataatacgga gcgccagtat agagaacctc cgtcacgggc agaaatgaat taaaatcatt
    28141 gcaggcatag tcggaaggaa taatcatgga tatcagaacg ctgcgttatt ttgtcgaggt
    28201 ggtgcgccag caaagtttca cccgcgcagc ggagaagtta tttgtcaccc agcccaccat
    28261 tagcaagatg ctgaaaaatc ttgaagatga gcttaactgt acgctactga tccgcgacgg
    28321 acgtaagtta ttgctgaccg ataccggacg cgtggtgttt gaacgcggtc tggcgatcct
    28381 cgctgagttt cgccagttag aggccgagtt gagcgatatt aaccatctca ataagggcgt
    28441 gctgcggctg ggtattcccc cgatggtcgg catgttgatg gctgggccaa tcagtttgtt
    28501 tcgacaacgc taccctggcg ttgaactcaa aatttcggag tttggcggcc tgacggtaca
    28561 gcaggcggta atgaatggcg agctggatgt tgcgatgacc gcgctcccgg tggaagaagc
    28621 gagcgggctg acgacattat cgctgttcag ccatccgctg tgcgtgctgg ttccccgttc
    28681 cggtcagtgg acaacctgcg actccatcgc gcctgaagct ctggcggagc atcctcttct
    28741 tatctataac gaagactttg ccctgagccg ccagttgatg accttattta gccagcatga
    28801 cgtaaaacca cggattgccg tgcgcagcgg gcaatgggat tttctcgccg ccatggtgca
    28861 agcgggcgtc ggcatcgcca ttttgccgga gccgatttgt cagcgtctgg ataaggccac
    28921 gctgcgctgg ctaccgctgg aaagtgatct ccgctggcag ttgggcatga tttggcgcga
    28981 gggcgtgtat ctgtcgcaca gcgcccgggc atggttaacc tgttgcgaag ggttttggct
    29041 gaaacaaccg taagccatgg gttaaaaccc ttgccggatg gcggcgcaag caccttaccg
    29101 ggcctacttg taggcccgat aagcatggcg ccaccgggcc acaaggacta ctgattttct
    29161 atcagtagag cttccatcaa atccaggtcg tgcagcagct tttgcaatgt ttcattgctg
    29221 atttctcgcg tggcgcgcag atgatacaac tcggcgcgtt cggaacgcag cgccgccaga
    29281 cggaaacgtc gctccaggtt ttcttcctgt atggagcttt cgacatcgtt tcgcccatcg
    29341 gcacggcgac gcaagttacc aatgacacgc gagcttactt cagtaagcaa ctgattatcg
    29401 atgttttctt cggtatccgc cgccagacgc tcttccattt tctgaatggc aacaatcgcc
    29461 acttccgccg tcgccgcgcg ggcgatacgc tcctctttca actgttgcgc atgatcggcg
    29521 acttccagat gttgcaacag cagcggcagc atgatcacgc cgacaaacaa cgagaacaga
    29581 atgacgccag ccgccaggaa taccagttca taacgcgccg gaaatccgct gccatccggc
    29641 aaaagtaacg gtatagagag cacaccagcc agggtgatcg ccccacgaac gccagcgaag
    29701 gaagcaatca gaatttcacg cgacgtccag ctggcgaact ccatcggttt cttcttcaaa
    29761 aagcgcaggc tgaacttttt catggtccac agccagccga agcgaaccag catcaatgcc
    29821 gcataaatca gcacgatatc ggtaaagagc atccaggttt cgacattcgg gtcagcttcc
    29881 gccgccgcca gcgaagattc cagaatccct ggcaattgca gtcccaacag cagaaagacc
    29941 ataccgttaa agacaaattc cagcatcgcc caggtactgt tcgcgcgcaa acgcattgcc
    30001 agcggcgcgc ggcgcattac gccagaacgg gtgatggtca tcccggcggc aaccgcggcc
    30061 aggatgcctg agacgccaat atgttcggca atcaggtaag acgcgaaggg cagcagaaac
    30121 agcaggacga tttgcgtcgc gggctcatcg ccgccccagc ggctcaaaaa acgcagcgag
    30181 cggccataca gccaactgac tacaaaaccc gccagaatac cgccgatagc gaccttaaaa
    30241 aattccagcg tcgcgccgcc gacggtaaag accatcgtcc ccatcgccac cgcgacggcg
    30301 aatttcagcg ataccagacc ggaggcgtcg ttcattaacg cctctccctg cagaatgccc
    30361 atgatttttt tcgggatacg cccctcgccc acaattccgg agagcgctac cgcatcggtc
    30421 ggcgacagca cggcggccag cgcaaatgcg gggatcagcg gaatgccggg caccagccaa
    30481 taaatcagga agccgattcc cacaaccgtt accaggacca gcgccagcgc cagcccgaaa
    30541 atctctcgtc catgctcaag aaattcacgg gtcggcgttt tccagccatc cgcaaacagc
    30601 agcggcggaa taaacagcac caggaagagt tccgggtcga attccacatg caaaccaaac
    30661 gtcggccacg ccaacagcgc gccaatggcg atctgcataa ggggtaaagg aagctggaag
    30721 ggtaatacac gcgtaaatac ccccgacagc gagaccacaa gggtcatgat gagtattgtg
    30781 aagaaaattt ccatgcgttc cctgtttgcg atgtttttta tgatggagaa aggcatcatg
    30841 cctcggtttc accttcttca gattaacgca aaaggtaacg tgatgtgtcc tgaaaatgaa
    30901 aacgggcgac caacgccgcc catttttcag aatgaaggca gaactagata gcccagccgc
    30961 cggcataaaa agcgaccagc gcgaccgcaa tgacgacagt tccgatattc agcttacgcc
    31021 attcaccaga aaccagacgc ccgacgacca gcgtggcaaa gccgatcata atcccggtga
    31081 cgatgttaca ggtcagtaca ataaatacag ccgttaccag ccccgccatc gcatcgacga
    31141 aatcagcaaa atcgattttc gccacgttac tcagcatcag cagaccgaca tacatgagcg
    31201 ccggggcggt tgcgtagacg ggaacgagat aagagagcgg cgaaagaaac aagatcagca
    31261 aaaacagcac gcccacggta atcgccgtca ggcccgtttt accacccgcc gccgtaccgg
    31321 ccgcagactc gatatacacc gcggctggcg ccgccccgac caggccggag aaaacgctac
    31381 tcagtgagtc ggtggttagc gctttgccgc catcgataat ttgtccgtct ctgtccagca
    31441 gattagcctg ccctgcgacc gcacgaatcg tgccggtcgc atcaaacacc gccgtcatca
    31501 ccagcgccag cacgcttggc agaacgacag ggtttaacgc gcccataata tccaggctgc
    31561 cgatcagcga gttgccgttt tcatcgctca acgaaggcat ggcgaaaatg ccggaaaaat
    31621 ggacgttagg atcgaagagc aaacccacaa tagaaatgcc aataatggtc aacagaatgc
    31681 cgccggggac tttcagcttt tccagaccga gaataacagc cagacccaca agcgacataa
    31741 tcaccgggaa ggtatcgaaa tcgcccagcg cgaccggcag gccatccagc gggtttttaa
    31801 tgaccaggcc gacgccgttg gcggcaatca gcaacaaaaa caggccaata ccgataccgg
    31861 ttccgtgggc cacgccctgc ggcaagttac gcaaaatcca gctacgaatg ccggtagcgg
    31921 agataatggt aaacagtacg cccatcagga atacggcgcc aagcgcgacc gggacgctaa
    31981 tatgctgccc caggaccagg ctaaacgcgg taaacgccgt caacgagata gcgcaaccga
    32041 tagccagcgg cagattcgcc catagcccca taacaataga gccgacgcct gcgaccaggc
    32101 aggtcgctac aaagacggcg gcaggcggga acccggcttt acccagcatc cctggcacca
    32161 cgatgacgga gtaaaccatc gcgagaaacg tggttaagcc agcaacgact tcctggcgaa
    32221 cggtgctccc gcgttgtgaa attttaaacc aggcgtcgag tgaaccgccg gtacgcgctg
    32281 aaggcgtaga catagaaaac atcccctgag aatttattat tcgtcggtat acgtgggagg
    32341 taatccacta acagcgcaac gttatctcct tgtgctacat ttacgacagc cggggcgccg
    32401 caaaaaagca aacgtttagc tccacgtata caaaacgggt ggcaaaaaaa agcaaacgat
    32461 tatccagcga tcatcaacgc tttttcaact gaactttgcc gctttttatg cttttctgct
    32521 tagtatgctc aataaatagc cagacgatgc gcaaacgtta tcgtccctgc gcaatccagc
    32581 aacaattttt cgcatcgctg ttagcaaata cgttgcgcaa tctgctcaca aaaacgccat
    32641 tatccgccgg gaatggtaaa cggaccgccc tgctgaatcg ctcgctgcca ggctggacgc
    32701 atttctaccc gcgctttcca tgcgttgata tggtcgagat gagcgattcc gcctcgggca
    32761 agcagcgcaa atagcgggaa gctcatctgg atatccgcca tacttaactg ctctccggca
    32821 aaccaggggt gatttgccag atgctcgtca ataaagcgcg catgggtttc cagttgcgga
    32881 ttgaggtacg ctttttgcgc gcccttaccg atcacgccgc ccaacgttcg caggcccaat
    32941 ggtaccggcg gtttacccag agaggtaaag agcagtctca tcaatagcaa gggcatgagc
    33001 gaaccttcag cgtaatgtag ccagaatcga tagtgttgtt ttctctgcgc atccgcaggc
    33061 ttaaagcgtc cgatattgtc gtaagtgtcc tgcaaatatt ccaggatggc gcccgattcc
    33121 gcaataacca taccgtgatc ttcgataacc ggagacttgc ccagcggatg cacttttttc
    33181 aatgccggcg gcgccagcat ggtcttttca cgctggtaac gcacaatctg gtaaggcaac
    33241 gccagctctt ccagcgccca gaggatgcgc tgcgaacgag actgatttaa atggtgcacc
    33301 gtcagcatgg ctgtctcctg taaggtatgc caactaacta tagaaaatta tggcagttgc
    33361 cgtaaaaatt tcggctaaaa aatcagcatt tcgctggcga acagggcgtc gtcgcttaca
    33421 cttacagtat caacacaaac cggaacctcc accacgtgct caatatgaga ggtgttgacg
    33481 tcgggggaaa ccctcctgta atcagcggga tagagcgaaa gacaaagacc ggaaacaaac
    33541 taaagcgccc ttagcggcgc tttagtttta ggtgagctca gcccgatggc cgagtgcatg
    33601 ttaatcatct tcaagcagcc gggcgcccgt cccgtgttcg ccaagcctgt cgcctggatt
    33661 ccgcagcgga cagtcgctac gcgataaaca gccgcagccg atacaaccgt ccagctcatc
    33721 gcgcaacgcc accagcgtat gaatacgtcg gtctaactct tcgcgccact gcgaggagag
    33781 ctgcttccac tctttcgcgc ttaacgtatg cccttccggc aagataccaa acgcgtcgcc
    33841 gatagttgcc agcgggatgc cgatacgctg ggcaatcttg ataatcgcga cataacgcaa
    33901 cacgtcacgc ttgtatcgcc gttggttacc gctattacgg atactggtaa ttagcccttt
    33961 gctttcatag aagtgcaggg cggacacagc aacaccgcta cgtttcgcaa cttcccccgg
    34021 cgtcagtaag gcttttaaac ggggagattt tttttccata aatcgcttta cctcaagtta
    34081 acttgaggaa ttatactcgc ccgcagacaa aacgacgaat cgaatactgt ttaagaggca
    34141 acaatatgtc gcatcagcag ataattcaga cccttatcga atggattgat gaacatatca
    34201 accaaccgct aaacattgat gtggtggcaa aaaaatcggg ttactccaag tggtatttgc
    34261 agcggatgtt tcgtacggta acgcatcaaa cattaggcga gtatattcgc cagcgccgtc
    34321 tcctgttagc ggccgttgag ctacgaacga ccgagcgccc gatttttgat atcgcgatgg
    34381 acctgggcta tgtatcgcag caaaccttct cgcgtgtatt ccgccgcgag ttcgatcgca
    34441 ctcccagcga ttaccgtcac cgcctgtagg gcgtctgccc gcgtatcgtc agaggcgcgg
    34501 gcgtttgttg tagccagacg atgaattcct gcggcggtaa cgccttcgca aagtgccatc
    34561 cctgacaata ctgcacgccg cgttttagca accagctaac ctgttcagcc gtttcaaccc
    34621 cctcagcaat gatttttagc cgcaaacttt gcgccatttc aataatatgt tccacaatca
    34681 aatggctggc gctattagtg gttagcgtat cgacaaaaga tttatcaatt tttaaaaggt
    34741 cgacatttaa tgagtacagg ttatgcaagt tcgaatagcc ggtaccaaag tcatcaattg
    34801 ctacctcgta tcccgcctgg cgaaacgcct gaataatcgg cgtcattttc ggcacatcaa
    34861 taaatccgcg ctcggtcact tcaaccttta tctgttgcgc aagcactgaa tgctgacgcg
    34921 ttttttcatg aatcatcaca attagtcggg aagagagaaa atcggcggca gagagattga
    34981 tagagacata aagatgcggg tgcgcggcca gaaaaccacc taaatcatta aatacctctt
    35041 cgacgacata atcggtgatc tgctcaatca tcccctcttt ttccgccaga ggaataaatt
    35101 cgcacgggct catcaccgga ccgtgataac ccggccaacg caatagcgct tcggcaccta
    35161 cacatgtccc gtttcggata tcaatgatcg gctgataatg aaggcaaagc tggtgcctgg
    35221 taatggcccg ttgcagcaat cgacgcggtg agtaatatgc ctgccgggat cgtgaccaca
    35281 taaataagac gataatgcta cagatgatcc ctaacggtag cgttaacgta agctgatgaa
    35341 agaggttctg gtaaaagcgt tgctttgagg ttgaaacaat cgcggcaacc ggtcgttttg
    35401 ctgatttaac cagagcatag aaacgctcac cctgttggaa cacaggttca ctccgttgta
    35461 ccaaaggtaa tagctgatca gcctgcgcct gttcactcag ggagaaaaag gtgttggtca
    35521 ccgtatcata cattccccag gccaacgccg gatcgtctga catcacctcg ctataagata
    35581 agggattgat aaccgcgaca tagtttcccc gctgcatata tgtcatttta taaccgttga
    35641 aaaaaggcgt atcacgatag taataaatag cgatgtcagg ctttcgttta tagtcagcgc
    35701 ggggaataaa ataaggactt gttggcgtca taaccgtaga gcatagaaaa cgctggccct
    35761 tagcataaat caactcatta atgtacaaac gaccgcggat aatattcagc attcgctgtt
    35821 gatgggctgg cgtacaggct tgcccctgat attgttcagc ggcatcgcgg gctaaatctg
    35881 cttgcaggat aacccgctcc gttttatcta ataccaactg cgcaaatgaa tgtaactgat
    35941 ttctggtttc agagactgcc cggatatgag caaaccagat cgccagcaat acaggaagta
    36001 ataccacaat gatcgttccg agaaatctca acaccttgcg tcgtgtgctt tgactcattt
    36061 tcagcctatt tccctgcatt atttgtgact attattggca aaataagacg tgaaccaaac
    36121 ggaggtttac ggtgcatgaa tttatcaata ttagcaacag acttttaccg atcaacattt
    36181 accattaata actacgcgca atctctttcg cataccaggc aggacactaa atatttttga
    36241 taatatcaga tttatactca agtaaacgat ggggtataca tctttactcc tttcttttga
    36301 taaataactt gatattttta tcaggtctga atttcacgaa aaaaaataaa agagtagtaa
    36361 taatacatct ttgctttccg gcagtttctc tacggacgcg cagaagtcac acaaaaaata
    36421 aggttataaa acgcacaaaa aatacattgc cgatctggcg aataagcctg tttttgtgat
    36481 atagttcaca aaaacaatga aacagaaaca atgtttcatt cgatgttgat gtgacgtccg
    36541 ttgatagcca gaatgtccca cgtttcccgg gaacaacgcc gtgctgtcct ggacaaaggt
    36601 ctattcagag gaaatgtttc atggctgcca taaccactgg tgtcgttctt ctccgctggc
    36661 aactgttgag cgccgtgctc atgtttttag ccagcacgct caatatccgt ttccgtaaat
    36721 cagattatat tggtctggcg gtgatcagta gcggtctggg cgtggtatcc gcctgctggt
    36781 ttgccaccgg tttactcggt attaccatga tggatctcgc tgcgatctgg cataacattg
    36841 aagccgtgat ggtcgaaacg atgagccaga ccccgccaga atggccgatg gtgctgacct
    36901 gatacgctat cgctgccgct gaagtcgccc accggttatc tcaaggcgga atcgcgcgcc
    36961 aggggtagcc ttgcgaacca tcacgtccct cgcattgccg ttgatgaggg ccgccaggtg
    37021 tggttatcca aaaatggcaa gtggaatagc cctaacagaa tcgagctaaa cttattgaag
    37081 acgttgccga ctcgttaaat gacaaaaaaa gacccgtttg tgcaacgggt cttttttatt
    37141 aagcagtacc acctgataac agcgacaagc gcggcttatt ttacattaat aatttatccg
    37201 gagaacaatc acggattatt tttccacctt tcattaccag gacccggtca aaatacttta
    37261 tcaggtatcg acgatgcgtc accatgatca acgttttccc atgaataaac tcatctaagt
    37321 tatcaaaaat ttgcttctcg gtattctcat ccagatttga tgttggttca tcccataaaa
    37381 agacgctggc gttactgctc agactacgtg ctaataataa ctgctgctgc tgtccggatg
    37441 acaggttttt agccataaaa ttcaccggaa acttcagccc cataggatgt tgcaagataa
    37501 aaccacagtt cgccagatga agcgccttga gtactcgtcc cctgtcgttt tgcggtttta
    37561 acgcgaaatt actttcaatg gttccggtga ataaaacatc atgtgtcgtc accacactta
    37621 aatgctgaga aaaaaagttc tgcgataaat gtcctaagtt atatccatca tataaaatgg
    37681 caccgtctgt tggcgaaagg tagccagata gcattcccag taatgagctt tttcctgcac
    37741 cgcattcgcc tatcactgcg acacgctgcc ccgcaggtat gtctatagac agtcgattaa
    37801 taatcatcgg agattgagca tcatactgat aactcacgcc ccgaatagag atatcgccat
    37861 tgcactttga tattgactgt aatgccggtg ttttttctgc ctgatcttca tcaaaaaaag
    37921 aaagcagatc cttaccggtt ttttctgctg ataaaataga gattaatgta gaagaaaaat
    37981 tcgaaatgat cccggaaata cgaccagaga caatgacaga tgaaacaatt gcgccagtag
    38041 taacatcacc cttgattacc ataaaaaagg ctatta
//
LOCUS       DAJVBX010000015        35928 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.015, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000015 DAJVBX010000000
VERSION     DAJVBX010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 35928)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35928)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35928
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.015"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..302)
                     /locus_tag="OPV72_000706"
     CDS             complement(<1..302)
                     /locus_tag="OPV72_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HCR9913081.1"
                     /translation="MKIKFLSLCILAGVLFANQVNASENNSKDDVKYAALTQKDFDAL
                     PVEKRASVLDELGFIHEYGLNVPMNREQALQYYKQACELGGNYGCYNVKYAYQHGDG"
     gene            477..607
                     /locus_tag="OPV72_000707"
                     /pseudo
     CDS             477..607
                     /locus_tag="OPV72_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491235.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            838..2202
                     /locus_tag="OPV72_000708"
     CDS             838..2202
                     /locus_tag="OPV72_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016507029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR9913082.1"
                     /translation="MNDYKMTPGELRATWGLGTVFSLRMLGMFMVLPVLTTYGMALQG
                     ASEALIGIAIGIYGLAQAIFQIPFGLLSDRIGRKPLIVGGLAVFVAGSVIAALSHSIW
                     GIILGRALQGSGAIAAAVMALLSDLTREQNRTKAMAFIGVSFGITFAIAMVLGPIVTH
                     SLGLNALFWMIAALATLGILLTIWVVPNSTNHVLNRESGMVKGSFSKVLAEPRLLKLN
                     FGIMCLHILLMSTFVALPGQLADAGFPAAEHWKVYLATMVIAFAAVVPFIIYAEVKRR
                     MKQVFLFCVGLIIVAEIVLWGAGQHFWELVIGVQLFFLAFNLMEALLPSLISKESPAG
                     YKGTAMGVYSTSQFLGVALGGSLGGWIDGTFDGQTVFLAGAVLAMVWLAVASTMKEPP
                     YVSSLRVEIPADIVADDRLKQRLLAMKGVSEALIVAEEHSAYVKIDSKVTNRFEVEQL
                     ISKG"
     gene            complement(2249..2740)
                     /locus_tag="OPV72_000709"
     CDS             complement(2249..2740)
                     /locus_tag="OPV72_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015965590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HCR9913083.1"
                     /translation="MPSFDIVSEVDLQEARNGVDNAVREVESRFDFRGVEATIELNDA
                     NKTIKVLSESDFQVNQLLDILRAKLLKRGIEGASLDVPDEFVHSGKTWYVEAKLKQGI
                     ESAVQKKIVKLIKDSKLKVQAQIQGEEIRVTGKSRDDLQSVMALVRGDDLGQPFQFKN
                     FRD"
     gene            2866..3777
                     /gene="panE"
                     /locus_tag="OPV72_000710"
     CDS             2866..3777
                     /gene="panE"
                     /locus_tag="OPV72_000710"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HCR9913084.1"
                     /translation="MKITVLGCGALGQLWLSALCKHGHDVQGWLRVPQPYCSVNLIDT
                     DGSFFNESLTANDPDFLAKSELLLVTLKAWQVSDAVRTLASTLPVTSPILLIHNGMGT
                     IEELQSIQQPMLMGTITHAARRDGNIIIHVANGTTHIGPAREQDGDYSYLAEILQGVL
                     PDVAWHNNIRAEMWRKLAVNCVINPLTALWNCPNGELRHHTDEINAICEEVAAVIERE
                     GYHTSADDLCYYVEQVIDSTAENISSMLQDVRAMRHTEIDYITGYLLKRARVHGLAVP
                     ENSRLFEMVKRKESEYERSGTGMPRPW"
     gene            3740..4330
                     /gene="yajL"
                     /locus_tag="OPV72_000711"
     CDS             3740..4330
                     /gene="yajL"
                     /locus_tag="OPV72_000711"
                     /EC_number="3.5.1.124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein deglycase YajL"
                     /protein_id="HCR9913085.1"
                     /translation="MSAQALVCLAPGSEETEAVTTIDLLVRGGIHVTTASVASDGNLT
                     IVCSRGVKLLADAPLVEVADGDYDIIVLPGGIKGAECFRDSPLLVETVKQFHRSGRIV
                     AAICAAAATVLVPHDIFPIGNMTGFPALKDKIPAEQWQDKRVVWDARVKLLTSQGPGT
                     AIDFGLKIIDLLVGREKAHEVASQLVMAAGIYNYYE"
     gene            complement(4427..5236)
                     /locus_tag="OPV72_000712"
     CDS             complement(4427..5236)
                     /locus_tag="OPV72_000712"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HCR9913086.1"
                     /translation="MNRIHAVILDWAGTTVDFGSFAPTQIFVEAFRQAFDVEITLAEA
                     RVPMGLGKWQHIEALGKLPTVDARWQAKFGRAMSAADIDAIYAAFMPLQIAKVVDFSS
                     PIAGVIDTIATLRAEGIKIGSCSGYPRAVMERLVPAAAEHGYRPDHWVATDDLVAGGR
                     PGPWMALQNVIALGIDAVAHCVKVDDAAPGISEGLNAGMWTVGLAVSGNEFGATWDAY
                     QTMSKEDVAVRREHAASKLYAAGAHYVVDSLADLPEVIAHINARLAQGERP"
     gene            complement(5246..6349)
                     /gene="phnW"
                     /locus_tag="OPV72_000713"
     CDS             complement(5246..6349)
                     /gene="phnW"
                     /locus_tag="OPV72_000713"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HCR9913087.1"
                     /translation="MTSRNYLLLTPGPLTTSRTVKEAMLFDSCTWDDDYNIGVVEQIR
                     QQLTALATASEGYTSVLLQGSGSYAVEAVLGSALGPQDKVLIVSNGAYGARMVEMAGL
                     MGIAHHAYDCGEVARPNVQAIDAILNADPTISHIAMVHSETTTGMLNPIDEVGALAHR
                     YGKTYIVDAMSSFGGIPMDIAALHIDYLISSANKCIQGVPGFAFVIAREQKLAACKGR
                     SRSLSLDLYAQWRCMEDNHGKWRFTSPTHTVLAFAQALKELAKEGGVAARHQRYQQNQ
                     RSLVAGMRALGFNTLLDDELHSPIITAFYSPEDPQYRFSEFYRRLKEQGFVIYPGKVS
                     QSDCFRIGNIGEVYAADITALLTAIRTAMYWTK"
     gene            6489..7208
                     /gene="phnR"
                     /locus_tag="OPV72_000714"
     CDS             6489..7208
                     /gene="phnR"
                     /locus_tag="OPV72_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate utilization transcriptional
                     regulator PhnR"
                     /protein_id="HCR9913088.1"
                     /translation="MKSIPGDIPQYLLIKAQLQARIQSGALKSGDKLPSERELCAIFN
                     TTRITIRESLAQLESSGLIWRADRRGWFVTPERLWLDPTQNTNFHKLCREQGREPKTA
                     LLSGVLTTVPVEVMEPLQLQPFDQIYLLTRLRYADGRAVCYCENHCLPARVPELLQYD
                     LNGSLTEVYESHYNLVYTSMHLSFYPTAMPAQAAQALGVMEGRPALLLRRLNYDQHGR
                     VLDLDIEYWRHDSLRIEVDTH"
     gene            7406..8419
                     /gene="phnS"
                     /locus_tag="OPV72_000715"
     CDS             7406..8419
                     /gene="phnS"
                     /locus_tag="OPV72_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HCR9913089.1"
                     /translation="MKLSRLALLSVFALASAPSWAESVVTVYSIDGLHDGDNSWYQVQ
                     FDAFTKATGITIRYVEGGGGVVVERLAKERTNPQADVLVTAPPFIQRAAAEKLLANFN
                     TDAASAIPDANNLYSPLVKNYLSFIYNSKLLKTAPASWQDLLDGKFKNKLQYSTPGQA
                     ADGTAVMLQAFHSFGSKDASFAYLGKLQANNVGPSASTGKLTALVNKGEIYVANGDLQ
                     MNLAQMERNPNVKIFWPANDKGERSALAIPYVIGLVQGAPQSENGKKLINFLLSKEAQ
                     TRVSELSWGMPVRSDVTPSDEHYKAATAALEGVQSWQPNWDDVAVSLSADISRWHKVT
                     ESE"
     gene            8425..9534
                     /gene="phnT"
                     /locus_tag="OPV72_000716"
     CDS             8425..9534
                     /gene="phnT"
                     /locus_tag="OPV72_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate ABC transport system
                     ATP-binding subunit PhnT"
                     /protein_id="HCR9913090.1"
                     /translation="MLMKTTAVHAPASQGTSGIVLDSLRVAYHGNVVLKPLSLTIEPG
                     EVLALIGPSGSGKTTVLRAVAGFVQPAGGRILIGDTDVTHLPPYKRGLAMVVQNYALF
                     PHLKVEDNVAFGLRAQKQPKALINERVTQALKTVGMSDYATRYPHQLSGGQQQRVAIA
                     RAIAVRPRVLLLDEPLSALDAQIRHNMVEEIARLHRELPELTILYVTHDQTEALTLAD
                     KIGIMKDGSLIAHGETRALYHHPPNRFAAEFLGRANILSAIALGITEVPGLVDVSCGG
                     AVIRAFSQGSHHGYNKLLCIRPQHLSLTPRSAYSNRFNATLQSVHWQGDLTHLLCDVA
                     GETVRMVLTHVNPLPRVGDKLALWFEPDDAVLIEV"
     gene            9537..10406
                     /gene="phnU"
                     /locus_tag="OPV72_000717"
     CDS             9537..10406
                     /gene="phnU"
                     /locus_tag="OPV72_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000052714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate ABC transporter permease
                     subunit"
                     /protein_id="HCR9913091.1"
                     /translation="MSLILPLEKPALNLRPLLWLLLPLLALATLFFWPLSLIVEQALR
                     GANGEIGLETFRQVVDSKRFVGALLNTLQIAFFATAGCLLLGSVMSLILVFIPFPGSE
                     LIGRVVDTFIALPTFLITLAFTFIYGSAGLLNGALMSLFAFELPPVDFLYSMQGVILA
                     EITVFTPLVMRPLMAALRQIDKSQLEAASILGAHPLRVIGQVIFPAALPALMASGSLC
                     LLLTTNEFGIVLFIGAKGVNTLPMMVYSKAILESDYTVACMIALINIVLSLGLFSLYR
                     LAASRTGVRSQPC"
     gene            10400..11191
                     /gene="phnV"
                     /locus_tag="OPV72_000718"
     CDS             10400..11191
                     /gene="phnV"
                     /locus_tag="OPV72_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate ABC transport system,
                     membrane component PhnV"
                     /protein_id="HCR9913092.1"
                     /translation="MLIWSPKGRAAAGVVASVLFIVFFFLPLAVILMSSLSQRWNGIL
                     PSGFTLNHFVNALHGAAWDALLASLTIGFCASLFALLCGVWAALALRQYGVKTQKWLS
                     MVFYLPSAIPSVSVGLGILVAFSQGPLQMNGTLWIVLTAHFVLISAFTFSNVSTGLAR
                     ISADIENVASSLGASPWYRLRHVTLPLLMPWMVSELALSLSLSMGELGATVMIYPPGW
                     TTLPVAIFSLTDRGNIADGAALTIVLVAITLLLMMKLERIAKRLG"
     gene            complement(11241..12689)
                     /gene="thiI"
                     /locus_tag="OPV72_000719"
     CDS             complement(11241..12689)
                     /gene="thiI"
                     /locus_tag="OPV72_000719"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014168857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HCR9913093.1"
                     /translation="MKFIIKLFPEITIKSQSVRLRFIKILTGNIRNVLKHYDETLAVV
                     RHWDNIEVRAKDENQRLAIRDALTRIPGIHHILEVEDVPFTDMHDIFEKALAQYREQL
                     EGKTFCVRVKRRGKHEFSSIEVERYVGGGLNQHIESARVKLTNPDVTVHLEVEDDRLL
                     LIKGRYEGIGGFPIGTQEDVLSLISGGFDSSVSSYMLMRRGCRVHYCFFNLGGAAHEI
                     GVRQVAHYLWNRFGSSHRVRFVAINFEPVVGEILEKVDDGQMGVVLKRMMVRAASKVA
                     ERYGVQALVTGEALGQVSSQTLTNLRLIDNVSDTLILRPLISYDKEHIINLARQIGTE
                     DFARTMPEYCGVISKSPTVKAIKAKIEAEEENFDFSILDKVVEEANNVDIREIAQQTQ
                     QEVVEVETVSGFGANDVILDIRSVDEQDDKPLKVEGVDVVSLPFYKLSTKFGDLDQSK
                     TWLLWCERGVMSRLQALYLREQGFANVKVYRP"
     gene            12899..13141
                     /gene="xseB"
                     /locus_tag="OPV72_000720"
     CDS             12899..13141
                     /gene="xseB"
                     /locus_tag="OPV72_000720"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HCR9913094.1"
                     /translation="MPKKNEAPASFETALSELEHIVTRLESGDLPLEDALNEFERGVQ
                     LARQGQAKLQQAEQRVQILLSDNEEASPEPFIADNE"
     gene            13142..14041
                     /gene="ispA"
                     /locus_tag="OPV72_000721"
     CDS             13142..14041
                     /gene="ispA"
                     /locus_tag="OPV72_000721"
                     /EC_number="2.5.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2E,6E)-farnesyl diphosphate synthase"
                     /protein_id="HCR9913095.1"
                     /translation="MDFTQQLQACVTQANQALSRFIAPLPFQNTPVVEAMQYGALLGG
                     KRLRPFLVYATGQMFGVSTATLDAPAAAVECIHAYSLIHDDLPAMDDDDLRRGLPTCH
                     IKFGEANAILAGDALQTLAFTIISDAPMPEVADRDRIAMIAELANASGIAGMCGGQAL
                     DLAAEGQRITLDALERIHRHKTGALIRAAVRLGALSAGDKGRNTLPILDRYAESIGLA
                     FQVQDDILDVVGDTATLGKRQGADQQLGKSTYPALLGLEQARNKARDLIEDARQSLHQ
                     LAAQSLDTSALEALANYIIQRDK"
     gene            14065..15927
                     /gene="dxs"
                     /locus_tag="OPV72_000722"
     CDS             14065..15927
                     /gene="dxs"
                     /locus_tag="OPV72_000722"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HCR9913096.1"
                     /translation="MSFDIAKYPTLALVDSTQELRLLPKESLPKLCDELRRYLLDSVS
                     RSSGHFASGLGTVELTVALHYVYNTPFDQLIWDVGHQAYPHKILTGRRDKIGTIRQKG
                     GLHPFPWRGESEYDVLSVGHSSTSISAGIGIAVAAEKEGKDRRTVCVIGDGAITAGMA
                     FEAMNHAGDIRPDMLVILNDNEMSISENVGALNNHLARLLSGKLYSSLREGGKKVFSG
                     VPPIKELLKRTEEHIKGMVVPGTLFEELGFNYIGPVDGHDVMGLISTLKNMRDLKGPQ
                     FLHIMTKKGRGYEPAEKDPITFHAVPKFDPSSGCLPKSSGGLPGYSKIFGDWLCETAA
                     KDSKLMAITPAMREGSGMVEFSRKFPDRYFDVAIAEQHAVTFAAGLAIGGYKPVVAIY
                     STFLQRAYDQVIHDVAIQKLPVMFAIDRAGIVGADGQTHQGAFDLSYLRCIPDMVIMT
                     PSDENECRQMLFTGYHYNDGPTAVRYPRGNAQGVALTPLEKLPIGKGLVKRHGEKLAI
                     LNFGTLMPEAAKVAEALNATLVDMRFVKPLDDTLILEMAAQHDALVTLEENAIMGGAG
                     SGVNEVLMAHRKPVPVLNIGLPDFFIPQGTQEEARAELGLDAAGIEAKIKAWLA"
     gene            15984..16958
                     /locus_tag="OPV72_000723"
     CDS             15984..16958
                     /locus_tag="OPV72_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HCR9913097.1"
                     /translation="MQYNTLGNTDLRVSRLCLGCMTFGEPSRGNHAWTLPEESSRPII
                     KRALEGGINFFDTANSYSDGSSEEIVGRALRDFARRDEVVVATKVFHRVGDLPEGLSR
                     AQILRSIDDSLTRLGMEYVDILQIHRWDYTTPIEETLEALNDVVKAGKARYIGASSMH
                     ASQFAQALALQKQHGWAPFVTMQDHYNLIYREEEREMLPLCWQEGVAVIPWSPLARGR
                     LTRPWGETTARLASDDVGKNLYDESDKNDAQIAERLAGVSEALGATRAQVALAWLLSK
                     RGVAAPIIGASREEQLDELLNAVDLTLKPEQIAELETPYKQHPVVGFK"
     gene            complement(17062..17577)
                     /gene="pgpA"
                     /locus_tag="OPV72_000724"
     CDS             complement(17062..17577)
                     /gene="pgpA"
                     /locus_tag="OPV72_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HCR9913098.1"
                     /translation="MTILPRHKDVAKSRLNLRNPWHLLATGFGSGLSPVVPGTMGSLA
                     AIPFWYLMTFLPWQLYSLVVMFGICIGVYLCHQTAKDMGVHDHGSIVWDEFIGMWITL
                     MALPTTDWQWVAAGFVIFRILDMWKPWPIRWFDRNVHGGMGIMIDDIVAGVISAGILY
                     FIGHHWPLGII"
     gene            complement(17555..18532)
                     /gene="thiL"
                     /locus_tag="OPV72_000725"
     CDS             complement(17555..18532)
                     /gene="thiL"
                     /locus_tag="OPV72_000725"
                     /EC_number="2.7.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-phosphate kinase"
                     /protein_id="HCR9913099.1"
                     /translation="MACGEFSLIARYFDRVRSSRLDVETGIGDDCALLNIPEKQTLAI
                     STDTLVAGNHFLPDIDPADLAYKALAVNLSDLAAMGADPAWLTLALTLPEVDEPWLEA
                     FSDSLFALLNYYDMQLIGGDTTRGPLSMTLGIHGYIPAGRALKRSGAKPGDWIYVTGT
                     PGDSAAGLAVLQNRLQVSEETDAHYLIQRHLRPTPRILHGQALRDIASAAIDLSDGLI
                     SDLGHIVKASGCGARVDVDALPKSDAMMRHVDDGQELRWALSGGEDYELCFTVPELNR
                     GALDVAIGQLGVPFTCIGQMSADIEGLNFVRDGMPVTFDWKGYDHFATP"
     gene            complement(18611..19030)
                     /gene="nusB"
                     /locus_tag="OPV72_000726"
     CDS             complement(18611..19030)
                     /gene="nusB"
                     /locus_tag="OPV72_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HCR9913100.1"
                     /translation="MKPAARHRARECAVQALYSWQLSQNDIADVEYQFLAEQDVKDVD
                     VLYFRELLSGVATNSAYLDGLMKPYLSRLLEELGQVEKAVLRIALFELSKRSDVPYKV
                     AINEAIELAKTFGAEDSHKFVNGVLDKAAPVIRPNKK"
     gene            complement(19051..19521)
                     /gene="ribE"
                     /locus_tag="OPV72_000727"
     CDS             complement(19051..19521)
                     /gene="ribE"
                     /locus_tag="OPV72_000727"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006818760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HCR9913101.1"
                     /translation="MNIIKANVAAPDARVAITIARFNQFINDSLLDGAVDALTRIGQV
                     KDDNITVVWVPGAYELPLATEALAKSGKYDAVVALGTVIRGGTAHFEYVAGGASNGLA
                     SVAQDSGVPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIKA"
     gene            complement(19610..20713)
                     /gene="ribD"
                     /locus_tag="OPV72_000728"
     CDS             complement(19610..20713)
                     /gene="ribD"
                     /locus_tag="OPV72_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HCR9913102.1"
                     /translation="MQDEFYMARALKLAQRGRFTTHPNPNVGCVIVNNGDIVGEGYHH
                     RAGEPHAEVHALRMAGAKAKGATAYVTLEPCSHHGRTPPCCDALIAAGVARVVAAMQD
                     PNPQVAGRGLYRLQQAGIAVSHGLMMSEAEALNKGFLKRMRTGFPYLQLKLGASVDGR
                     TAMASGESQWITSPQARRDVQRLRAQSHAILTSSATVLADDPALTVRWAELDASTQAS
                     YPQENLRQPVRIVIDSQNRVTPAHRIVQQPGETWIARTQEDSHAWPDSVRTISVPAHN
                     GHLDLVVLMMQLGRQQINSIWVEAGPGLAGALLQAGLVDELIVYVAPKLLGTQARGLC
                     ELPGLEKLADAPQFTFSEIRHVGPDVCLHMVSA"
     gene            complement(20717..21166)
                     /gene="nrdR"
                     /locus_tag="OPV72_000729"
     CDS             complement(20717..21166)
                     /gene="nrdR"
                     /locus_tag="OPV72_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017458860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HCR9913103.1"
                     /translation="MHCPFCFAVDTKVIDSRLVGEGSSVRRRRQCLVCNERFTTFEVA
                     ELVMPRVIKSNDVREPFNEDKLRSGMLRALEKRPVSADDVEMALNHIKSQLRATGERE
                     VPSKMIGNLVMEQLKKLDKVAYIRFASVYRSFEDIKDFGEEIARLQD"
     gene            21318..21857
                     /locus_tag="OPV72_000730"
     CDS             21318..21857
                     /locus_tag="OPV72_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3251 domain-containing protein"
                     /protein_id="HCR9913104.1"
                     /translation="MTRRYLRILLVGSLLSLTACAPQSEVRQMHQSISTLNKEMTQLN
                     QETVKITQQNKLNADSTRGVYLLPGANTPARLESQIGTLRMTLLEITPVADGAHATLR
                     IQGKSRDPLPAFSATVEYGQIQGTTENYQEVNAQSLLVNAPASLLAPSDVNIPLPLKG
                     ITPAQLGFIRIHDIQPVNQ"
     gene            22157..23020
                     /locus_tag="OPV72_000731"
     CDS             22157..23020
                     /locus_tag="OPV72_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-specific channel-forming protein Tsx"
                     /protein_id="HCR9913105.1"
                     /translation="MKKTLLAVSAALALTSSFTANAAENDQPQYLSDWWHQSVNVVGS
                     YHTRFSPKLNNDVYLEYEAFAKKDWFDFYGYIDIPKTFDWGNGNDKGIWSDGSPLFME
                     IEPRFSIDKLTGADLSFGPFKEWYFANNYIYDMGDNKASRQSTWYMGLGTDIDTGLPM
                     GLSLNVYAKYQWQNYGASNENEWDGYRFKVKYFVPITDLWGGKLSYIGFTNFDWGSDL
                     GDDPNRTSNSIASSHILALNYDHWHYSVVARYFHNGGQWQNGAKLNWGDGDFSAKSTG
                     WGGYLVVGYNF"
     gene            complement(23103..23210)
                     /locus_tag="OPV72_000732"
     CDS             complement(23103..23210)
                     /locus_tag="OPV72_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin Ldr family
                     protein"
                     /protein_id="HCR9913106.1"
                     /translation="MTLTELSITIWHDLAAPTLVGIATGLFLGWWHRRK"
     gene            complement(23653..24000)
                     /locus_tag="OPV72_000733"
     CDS             complement(23653..24000)
                     /locus_tag="OPV72_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH nuclease family protein"
                     /protein_id="HCR9913107.1"
                     /translation="MAIIPKNYARLESGYREKALKLFPWVCGRCSREFVYSNLRELTV
                     HHIDHDHTNNPEDGSNWELLCLYCHDHEHSKYTEADQYGSTVIAGEDAQKDVGEATYN
                     PFADLKAMMNKKK"
     gene            complement(24170..24862)
                     /locus_tag="OPV72_000734"
     CDS             complement(24170..24862)
                     /locus_tag="OPV72_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HCR9913108.1"
                     /translation="MTRRADRLFQIVQILRGRRLTTAALLAQRLAVSERTIYRDIRDL
                     SLSGVPVEGEAGSGYRLMAGFDLPPLMLTHRESEALMVAIRLLKTWGGDSLSRELESA
                     QEKVLAILPEESRRKAEQTRIYAPDLGTSPHSRSAFDLIHQAVSAQQVLALHYRDEAG
                     HLSSRDIQPLGLFFWGEHWLLVAWCERREDYRCFRLDRCLQITPLNRRFRETIDRSLR
                     DFLRKVEHEKMP"
     gene            complement(24888..25253)
                     /locus_tag="OPV72_000735"
     CDS             complement(24888..25253)
                     /locus_tag="OPV72_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCR9913109.1"
                     /translation="MKNLINWFEIPVTDMARAIAFYEQVMQISLRRETMDGADLAVFP
                     YAEPGPGGALIKQDDVAPVAQGVVIYLHTADLLASIERVVLAGGKCVLEPMVPGDDIG
                     TIALFIDSEGNRIGLHQPA"
     gene            complement(25400..26371)
                     /gene="secF"
                     /locus_tag="OPV72_000736"
     CDS             complement(25400..26371)
                     /gene="secF"
                     /locus_tag="OPV72_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein translocase subunit SecF"
                     /protein_id="HCR9913110.1"
                     /translation="MAQEYTVEQLNHGRKVYDFMRWDFWAFGISGLLLIAAIVIMGVR
                     GFNWGLDFTGGTVIEITLEKPAEMDVMREALQKAGYEEPQLQNFGSSHDIMVRMPPTE
                     GETGGQVLGSKVVTIINEATNQNAAVKRIEFVGPSVGADLAQTGAMALLVALISILVY
                     VGFRFEWRLAAGVVIALAHDVIITLGILSLFHIEIDLTIVASLMSVIGYSLNDSIVVS
                     DRIRENFRKIRRGTPYEIFNVSLTQTLHRTLITSGTTLVVILMLYLFGGPVLEGFSLT
                     MLIGVSIGTASSIYVASALALKLGMKREHMLQQKVEKEGADQPSILP"
     gene            complement(26382..28229)
                     /gene="secD"
                     /locus_tag="OPV72_000737"
     CDS             complement(26382..28229)
                     /gene="secD"
                     /locus_tag="OPV72_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein translocase subunit SecD"
                     /protein_id="HCR9913111.1"
                     /translation="MLNRYPLWKYIMLVVVIIVGLLYALPNLYGEDPAVQITGVRGVA
                     ASEQTLIQVQKTLQEEKIPAKSVALEEGAILARFDTTDTQLRAREALMSVLGDKYVVA
                     LNLAPATPRWLAAIHADPMKLGLDLRGGVHFLMEVDMDTALGKLQEQNIDSLRSDLRE
                     KGIPYTTVRKENNYGLSITFRDSKARDEAIAYLTPRHRDLVISSQSGNQLRAVMTDAR
                     LSEAREYAVQQNINILRNRVNQLGVAEPVVQRQGADRIVVELPGIQDTARAKEILGAT
                     ATLEFRLVNTNVDQAAAAAGRVPGDSEVKQTREGQPVVLYKRVILTGDHITDSTSSQD
                     EYNQPQVNISLDSAGGNIMSNFTKDNIGKPMATLFVEYKDSGKKDANGRAVLVKQEEV
                     INIANIQSRLGNSFRITGISNPNEARQLSLLLRAGALIAPIQIVEERTIGPTLGMQNI
                     KQGLEACLAGLVVSILFMIFFYKKFGLIATSALVANLVLIVGIMSLLPGATLSMPGIA
                     GIVLTLAVAVDANVLINERIKEELSNGRTVQQAINEGYAGAFSSIFDANITTLIKVII
                     LYAVGTGAIKGFAITTGIGVATSMFTAIIGTRAIVNLLYGGKRVTKLSI"
     gene            complement(28257..28589)
                     /gene="yajC"
                     /locus_tag="OPV72_000738"
     CDS             complement(28257..28589)
                     /gene="yajC"
                     /locus_tag="OPV72_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000007628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HCR9913112.1"
                     /translation="MSFFISDAVAATGAPAQGSPMSLILMLVVFGLIFYFMILRPQQK
                     RTKEHKKLMDSIAKGDEVLTNGGLVGRVTKVAEAGYIAIALNDTTEVVIKRDFVAAVL
                     PKGTMKAL"
     gene            complement(28612..29739)
                     /gene="tgt"
                     /locus_tag="OPV72_000739"
     CDS             complement(28612..29739)
                     /gene="tgt"
                     /locus_tag="OPV72_000739"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HCR9913113.1"
                     /translation="MKFELDTTDGRARRGRLVFDRGVVETPAFMPVGTYGTVKGMTPE
                     EVEATGAQIILGNTFHLWLRPGQEIMKLHGDLHDFMQWKGPILTDSGGFQVFSLGDIR
                     KITEQGVHFRNPINGDPIFLDPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSME
                     MSLRWAKRSRDRFDSLGNKNALFGIIQGSVYEDLRDISVKGLVEIGFDGYAVGGLAVG
                     EPKADMHRILEHVCPQIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGH
                     LFVTDGVVKIRNAKHKSDISPLDAECDCYTCRNYSRAYLHHLDRCNEILGARLNTIHN
                     LRYYQRLMAGLRKAIEEGKLESFVTEFYQRQGRPVPPLNVD"
     gene            complement(29936..31000)
                     /gene="queA"
                     /locus_tag="OPV72_000740"
     CDS             complement(29936..31000)
                     /gene="queA"
                     /locus_tag="OPV72_000740"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HCR9913114.1"
                     /translation="MRVTDFSFELPESLIAHYPQPERSRCRLLSLEGPTGALTHGTFT
                     DLLDKLNPGDLLVFNNTRVIPARLFGRKASGGKIEVLVERMLDDKRILAHIRASKAPK
                     PGTELLLGDDESIHATMTARHGALFEVEFNDPRPVLDILNAIGHMPLPPYIDRPDEDA
                     DRELYQTVYSEKPGAVAAPTAGLHFDEPLLAALREKGVEMAFVTLHVGAGTFQPVRVD
                     TIEDHIMHSEYAEVPQEVVDAVLAAKARGNRVIAVGTTSVRSLESAAQAAKSDLIEPF
                     FGDTQIFIYPGYQYKVIDALITNFHLPESTLIMLVSAFAGYQHTMNAYKTAVEQKYRF
                     FSYGDAMFITCNPQAISERP"
     gene            31094..31675
                     /gene="acpH"
                     /locus_tag="OPV72_000741"
     CDS             31094..31675
                     /gene="acpH"
                     /locus_tag="OPV72_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP phosphodiesterase"
                     /protein_id="HCR9913115.1"
                     /translation="MNFLAHLHLAHLADSSLSGNLLADFVRGNPATHYPPDVVEGIYM
                     HRRIDVMTDNLPEVREAREWFRHETRRVAPITLDVMWDHFLSRHWTQISPDFPLQAFV
                     GYAHAQVATILPDSPPRFVNLNDYLWSEKWLERYRDMDFIQNVLNGMANRRPRLDALR
                     DSWYDLDAHYDALEERFWHFYPRMMAQAARKAL"
     gene            31885..32487
                     /locus_tag="OPV72_000742"
     CDS             31885..32487
                     /locus_tag="OPV72_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HCR9913116.1"
                     /translation="MVLVTRQAPDFTAAAVLGSGEIVDKFNFKQHTNGKTTVLFFWPM
                     DFTFVCPSELIAFDKRYEEFQKRGVEVVGVSFDSEFVHNAWRNTPVDKGGIGPVKYAM
                     VADVKREIQKAYGIEHPDEGVALRGSFLIDANGIVRHQVVNDLPLGRNIDEMLRMVDA
                     LQFHEEHGDVCPAQWEKGKEGMNASPDGVAKYLAENISSL"
     gene            complement(32559..34376)
                     /gene="malZ"
                     /locus_tag="OPV72_000743"
     CDS             complement(32559..34376)
                     /gene="malZ"
                     /locus_tag="OPV72_000743"
                     /EC_number="3.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrin glucosidase"
                     /protein_id="HCR9913117.1"
                     /translation="MLNAWHLPVAPFVKQHNDKLTITLWLSGENPPSRVTLRSEFDNE
                     EISLAMRKQRRQPQPGVTAWRATLNIALGQPRRRYSFKLLWHDRQRWFTPQGFSCFPP
                     ARLEQFAVDVPDSGPQWVADQIFYQIFPDRFARSATREADQDRVYYHHAAGQEIVLRD
                     WDDPLTPQAGGSTFYGGCLNGICEKLPYLKKLGVTALYLNPVFTAPSVHKYDTEDYRH
                     VDPQFGGDRALLRLRRETQAQGMRLVLDGVFNHSGDSHAWFDRHNRSTGGACHHPDSP
                     WRDWYSFSPQGVALDWLGYPSLPKLDYQSETLVDEIYRGEDSIVRHWLKAPWNMDGWR
                     LDVVHMLGEAGGARHNLQHVAGITRAAKEAQPEAYIVGEHFSDARQWLQADAEDAAMN
                     YRGFTFPLWGFLANTDIAYEPQHIDARTCIAWMDNYRAGLSHQQQLRMFNQLDSHDTA
                     RFKTLLGKDAARLPLAVVWLFTWPGVPCIYYGDEVGVDGANDPMCRKPFPWDERKQDG
                     NLLALYQRMAKLRQSSLALRRGGCQALYAEGDVVVFVRVYQQQRALVAINRGEACEVA
                     LEALPLLNVAGWQCKTGSGDIREGRLSLPAISATVWMNR"
     gene            complement(34538..35908)
                     /gene="proY"
                     /locus_tag="OPV72_000744"
     CDS             complement(34538..35908)
                     /gene="proY"
                     /locus_tag="OPV72_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline-specific permease ProY"
                     /protein_id="HCR9913118.1"
                     /translation="MESNNKLKRGLSTRHIRFMALGSAIGTGLFYGSADAIKMAGPSV
                     LLAYIIGGVAAYIIMRALGEMSVHNPAASSFSRYAQENLGPLAGYITGWTYCFEILIV
                     AIADVTAFGIYMGVWFPAVPHWIWVLSVVLIICAINLMSVKMFGELEFWFSFFKVATI
                     IIMIVAGIGIIVWGIGNGGQPTGIHNLWSNGGFFSNGWLGMIMSLQMVMFAYGGIEII
                     GITAGEAKDPEKSIPRAINSVPMRILVFYVGTLFVIMSIYPWNQVGTNGSPFVLTFQH
                     MGITFAASILNFVVLTASLSAINSDVFGVGRMLHGMAEQGSAPKVFAKTSRRGIPWVT
                     VLVMTIALLFAVYLNYIMPENVFLVIASLVTFATVWVWIMILLSQIAFRRRLPPEEVK
                     ALKFKVPGGVVTTIAGLIFLVFIIALIGYHPNTRISLYVGFAWIVLLLIGWIFKRRRD
                     RQLAQA"
BASE COUNT         8299 a        10104 c         9460 g         8065 t
ORIGIN      
        1 ccgtcgccat gctgataagc atacttcaca ttatagcaac cgtagttacc gccaagctca
       61 caggcctgct tataatactg caacgcctgt tcgcgattca tcggtacatt aaggccgtat
      121 tcatggataa accccagttc atccagaacc gaagctcttt tttccacagg caaagcatca
      181 aaatccttct gggtaagcgc agcgtatttt acatcatctt tactgttgtt ctctgatgca
      241 ttcacctggt tagcaaataa aacacctgct aaaatacata atgataagaa tttaattttc
      301 acaactaatt cactccttga ataatataat aaataagact gatgactaac cttctgcctg
      361 ataaacgcgc gccatcacgc agaaagtttg ctatcagtct cggcgttgtt gaataaatca
      421 aattttcagg agatggacgg ttctgatcat tgccatcgtt tcagaatcgg gtccctatgg
      481 caaagcaaaa gtttaaagtc acccactggc cagccacact caggcagcgc ggttcgctga
      541 cagtctgact tgacgagcct gctattgcta tatgaagcaa cagcgtacac agcctgaagg
      601 ccgtggctaa ccgctacact atactgagat ggctcagata gccactacag ctcaaggaga
      661 tcggaatatg aatgagcaca aggctatgct gactctcccg atcgccccta tcgtgttaac
      721 aatttatctc ttttttagct caactgtttc aaaaacataa tatttgctaa ttaaccctct
      781 atttacccgg cacactcccc gcactacact actcccagct tttatacaga ggtggcaatg
      841 aacgattata aaatgacgcc aggggagctg cgcgccacat ggggtttagg gaccgtcttt
      901 tcgttgcgta tgctgggcat gtttatggtt ctaccagtac tgaccacata cggtatggcg
      961 ctacagggcg ccagcgaagc attaatcggc attgcgatcg gtatttacgg gctggcgcag
     1021 gctatctttc aaattccctt tgggctgctg tccgaccgca ttggccgtaa accgctgatt
     1081 gtcggcggac tggcggtatt tgtcgcgggt agcgtcattg ccgcgctctc ccactctatc
     1141 tggggcatta ttctggggcg agcgctacag gggtccggcg ctattgccgc cgccgtcatg
     1201 gcgctcctgt ctgatctgac ccgagagcaa aaccgcacca aagcgatggc gtttatcggc
     1261 gtcagctttg gtatcacctt cgcgattgcg atggtattag ggccgattgt tacccatagt
     1321 ctgggattga acgcgttgtt ctggatgatc gccgccctcg ccaccctggg cattcttctg
     1381 acgatctggg tggttcccaa cagtaccaac catgtgctga atcgcgaatc cgggatggtc
     1441 aaaggcagct tcagtaaagt gctggcggag ccgaggctgc tcaagctcaa cttcggcatc
     1501 atgtgtctgc atattttatt gatgtccacc tttgtcgccc tgcccggcca gcttgccgat
     1561 gccggtttcc ctgccgccga acactggaag gtgtatctgg caaccatggt gatcgccttt
     1621 gccgccgtcg tgccttttat catctatgct gaagtcaaac ggcggatgaa gcaggtattc
     1681 ctgttctgcg tggggctcat tatcgtcgca gaaatcgtgt tgtggggagc gggccagcat
     1741 ttctgggagc tggtgattgg cgtacaactc tttttcctcg cctttaatct gatggaggcg
     1801 ctgctgcctt cgcttattag caaagagtcg cccgcggggt ataaaggaac ggcgatgggc
     1861 gtctattcta ccagtcagtt tcttggcgtg gcgcttggcg gctcgctggg cggctggata
     1921 gacggcacgt ttgatgggca aaccgttttc cttgccgggg ccgtactggc gatggtatgg
     1981 ctggcggtgg caagtaccat gaaagagccg ccctatgtca gcagcctgcg tgtggaaatt
     2041 ccagcggata tcgttgctga cgacaggcta aaacagcgac tgttggcaat gaaaggcgta
     2101 agcgaagcgc tgatcgtggc ggaagagcat tccgcttacg tcaaaatcga cagcaaagtg
     2161 accaatcgct ttgaagttga acagcttatc agcaaaggat gaatgcagca ttgccggatg
     2221 gcggcgaggc tctatccggc ataacaactt aatcgcggaa gtttttgaac tggaacggct
     2281 ggcctaaatc gtcgccgcga accagcgcca ttaccgattg cagatcgtca cgtgatttgc
     2341 ccgtcacgcg aatctcttcc ccctgaattt gcgcctgcac cttcagtttg ctgtctttaa
     2401 tcagcttgac gattttcttc tgcacggcgc tttcaatgcc ctgcttcagc ttcgcttcca
     2461 cataccaggt tttaccgcta tgcacgaact cgtccggtac atccagcgaa gcgccttcaa
     2521 taccgcgttt aagcagcttg gcgcgcagaa tatcgagcaa ctgattgacc tggaaatcgg
     2581 actcgctcag caccttgatg gttttattgg catcgttcag ttcaatagtc gcctctacgc
     2641 cacgaaagtc aaaacgagac tcaacctcgc gaaccgcgtt atccacgccg ttacgcgctt
     2701 cctgcagatc aacttcagaa acaatatcga aagatggcat cttttcttct cccttcattt
     2761 tcgttgcgtt gcataatacc tgcaacgagg cttaacgaga agcttagctg atgacgctat
     2821 aattagcgcc ataacacctg gcgctgttgc aggtgaggag gaacaatgaa aattactgta
     2881 ctgggatgcg gagccttagg acaactttgg ctttcggcac tgtgcaaaca tggacatgac
     2941 gtacagggct ggctacgggt gccacaacct tattgcagcg taaatctgat cgataccgat
     3001 ggttcctttt tcaacgaatc actgacggca aacgatccgg attttttggc gaagagcgaa
     3061 ctgttgttag tcacgctgaa agcgtggcag gtttccgacg cagtacgaac cctggcgtca
     3121 accctaccgg tgacgtcgcc tatcctgctc attcataatg gaatgggaac catagaagaa
     3181 ctgcaaagta tccaacagcc gatgttgatg gggactatca cccatgctgc gcgccgcgac
     3241 ggtaatatca ttattcatgt cgctaacggt actacgcata ttggcccggc gcgcgagcaa
     3301 gacggcgatt acagttatct cgccgagatc ctgcaagggg tactgcccga tgtcgcctgg
     3361 cataacaata tccgcgcaga gatgtggcgc aaactggccg tcaactgtgt tatcaacccg
     3421 ctcaccgcgc tttggaactg cccgaacggc gagctgcgcc atcatactga tgaaatcaac
     3481 gcgatttgcg aagaggtcgc cgccgtgatt gaacgtgagg gctaccacac atcggcagac
     3541 gatttatgct attatgttga gcaagtgatt gacagtacgg cagaaaatat ctcatccatg
     3601 ttgcaggacg tgcgcgccat gcgccatacc gaaattgact acatcaccgg ttatttactc
     3661 aagcgcgccc gcgtgcacgg tctcgccgtt ccggaaaata gccgcctgtt tgaaatggta
     3721 aagcgaaagg agagtgagta tgagcgctca ggcactggta tgcctcgccc ctggtagtga
     3781 agagaccgaa gcggtcacca ctatcgatct gctggttcgc ggcggaatcc acgtcactac
     3841 cgccagcgtc gccagcgatg gcaacctgac gattgtctgc tcgcgcggcg tgaagctgct
     3901 ggcggatgcg ccgctggttg aagttgccga cggcgattat gacatcatcg tgttgcccgg
     3961 cggaattaaa ggcgccgagt gctttcgcga cagcccgctg ctggtcgaaa ccgtaaaaca
     4021 gtttcaccgc tccgggcgca ttgtcgcagc catttgcgcc gcagccgcta cagtgctcgt
     4081 gccgcacgat atcttcccta tcggcaatat gaccggtttt ccggcgctga aagataagat
     4141 ccccgccgaa cagtggcagg ataagcgtgt ggtgtgggat gcgcgggtaa aattattaac
     4201 cagccaggga ccgggtaccg ctatcgattt tggcttgaaa atcatcgacc tgttggttgg
     4261 tcgtgaaaaa gcgcatgaag tggcttcgca actggtgatg gcggcgggga tttataacta
     4321 ctacgaataa gaatgattgc cggatggcgg cgtaaacacc ttatccggcc tacaaaacgg
     4381 tacagtctgt aggccggata agcggcagcg ccatccggca gttattttac gggcgttcgc
     4441 cctgcgccag acgcgcatta atatgcgcaa tcacctcagg taaatccgcc agtgaatcca
     4501 ccacgtaatg cgccccggcg gcgtacagct tgctggccgc gtgctcgcgg cggaccgcaa
     4561 cgtcctcttt cgacattgtc tgataggcgt cccatgttgc gccgaattcg ttacccgata
     4621 ccgccagccc caccgtccac atccccgcgt taagcccctc gctaatgccc ggcgcggcat
     4681 catctacctt cacgcagtgc gcgaccgcat caatgcccag cgcaatcacg ttttgcagcg
     4741 ccatccacgg ccccgggcga ccacccgcga ccaggtcgtc cgttgccacc caatgatccg
     4801 gacgataacc atgctcagcg gcggcgggaa ccaggcgctc catcaccgct cgtgggtaac
     4861 cggagcagga gcctatcttg ataccctcgg ctcgtagcgt cgcgatcgtg tcgataactc
     4921 cggcaatagg agaagaaaaa tcgacaactt tagcaatctg taacggcatg aaagcggcgt
     4981 agatggcatc aatatctgct gcgctcatgg cgcggccaaa ctttgcctgc cagcgcgcgt
     5041 caacagtagg taattttccc agcgcttcaa tgtgttgcca tttacccagc cccattggca
     5101 cgcgtgcttc ggcgagggtg atctccacat caaatgcctg acggaacgcc tcgacgaaaa
     5161 tttgcgtcgg cgcgaaggag ccaaaatcga cggtggtgcc cgcccagtcg agaataacag
     5221 cgtgaatacg gttcatcatg gttccttatt tcgtccagta catggcggta cgaatggcgg
     5281 tcagcagggc agtgatatcg gcggcatata cttcgccaat gttgccgatg cggaagcagt
     5341 cgctttgcga caccttgcct ggatagataa caaagccctg ctctttgagg cggcgataaa
     5401 attcgctaaa gcgatactgc gggtcttccg gtgaataaaa ggcggtgata atgggcgaat
     5461 gaagctcgtc atccagcagc gtgttaaagc ccagcgcccg cattccggcc accaggctgc
     5521 gctgattttg ctgatagcgt tgatgacgtg ccgccacgcc accttctttc gccagctctt
     5581 tcagcgcctg tgcaaacgcc aggacggtat gtgtgggcga agtaaaacgc catttgccgt
     5641 ggttatcctc catgcagcgc cactgggcgt agagatctaa cgacagcgag cgggaacgcc
     5701 ctttgcacgc ggccagtttt tgctcgcggg caatcacaaa ggcaaaaccc ggcacgccct
     5761 ggatgcattt attagcggag ctgatcagat agtcgatgtg taatgctgca atatccatgg
     5821 ggatgccgcc gaagctgctc atggcgtcaa cgatgtaggt tttgccatag cgatgcgcca
     5881 gagcgccaac ctcatcaatg gggttgagca tcccggtggt cgtttcgcta tgcaccatgg
     5941 cgatatggct gatcgtcggg tcggcgttga ggatcgcgtc gatcgcctgc acgttcgggc
     6001 gcgcaacttc gccgcagtcg taagcgtgat gggcgatacc cataaggccg gccatctcga
     6061 ccattcgtgc gccgtatgca ccgttgctga cgatcagcac cttatcctgc ggccccaatg
     6121 cgcttcccag tacggcttcc acagcatagc tgccgctgcc ttgcagcagt acggaggtgt
     6181 agccttcgga ggccgttgcc agtgcggtca actgctggcg gatctgttct accacgccga
     6241 tattgtaatc atcatcccag gtacagctat cgaacaacat cgcttctttc acggtgcgag
     6301 aggtggtgag tgggccaggg gtcagcaaca gatagttacg cgaagtcata tcatttacct
     6361 ttggtctata ccagattgca tttatcatga cgatctttgc cgcgatgggt caaagagaaa
     6421 atcgcgctgc aacaaaaaat tcatctctgc ttgtataatg gcggcaggta aaacggaagc
     6481 gagtaagcat gaaatctatc ccgggcgata tcccgcagta cctgttgatc aaggcgcagc
     6541 ttcaggcgcg tattcagagc ggtgcgttga aaagcggtga taaactgccg tctgaacgcg
     6601 aactgtgcgc gatcttcaac accacgcgca ttactattcg cgaaagcctg gcgcagctgg
     6661 agtccagtgg gcttatctgg cgcgccgatc gtcgcggttg gttcgttacg ccggaacgcc
     6721 tgtggctgga tccgacccag aacaccaact tccataagct ttgccgcgag caggggcggg
     6781 agccaaaaac cgcgctactg agcggcgtgt taaccaccgt gcctgtcgag gtcatggagc
     6841 ccctccagct ccagccgttt gatcaaatct atctgctgac ccgtctgcgt tacgccgatg
     6901 gccgcgccgt gtgctactgc gaaaaccatt gtttgcccgc ccgcgtgcct gagctgctgc
     6961 agtacgatct caacggcagc ctgaccgagg tatacgagtc gcactacaac ctcgtctata
     7021 ccagcatgca tctgtcgttc taccccaccg ccatgcctgc gcaggccgca caggcgctgg
     7081 gagttatgga aggacgcccg gcgctgttgc tgcgccgtct gaactacgat caacacgggc
     7141 gagtgctgga tctggatatc gaatactggc gtcacgacag cctgcgcatt gaggtagata
     7201 cccactagcg ggtgcgccgg atgttggctg cgggccttat ccggcctgtc aatcgtatcg
     7261 tctcacggct atcccgataa gcgcagcatc atccggcgtg gactgattta tttctctttc
     7321 atcgttttgt catataagcc gtttagcgta aaaagcaaac ctggtatagg ccagaaaatg
     7381 caacgtacgc tatgaggcta ttacgatgaa actttcccga cttgctctgc tgtctgtctt
     7441 cgctctcgcc agcgccccgt catgggcgga atcagtggtc acggtgtact ccatcgacgg
     7501 gctgcacgat ggcgataaca gctggtacca ggtgcagttt gacgcgttca ccaaagcgac
     7561 cggcattacc atacgctatg ttgaaggcgg tggtggcgtg gtagtggaac gtctggcaaa
     7621 agagcgtacg aatccacagg ccgacgtgct ggtaaccgcg ccgccattca ttcagcgcgc
     7681 cgccgccgaa aagctgctgg cgaactttaa caccgacgcc gcctcggcta tccccgatgc
     7741 caacaacctt tattcgccgc tggtaaagaa ttatctgagc tttatctaca acagcaagct
     7801 gctgaaaact gccccggcga gctggcagga tctgcttgac ggtaaattca aaaataaact
     7861 ccagtattcc acgccaggtc aggccgctga cggcacggcg gtaatgctgc aggctttcca
     7921 cagcttcggc agtaaagatg ccagttttgc gtatctcggc aagctgcagg ccaataacgt
     7981 cgggccatct gcctctaccg gcaagctaac cgcgctggtt aataaaggtg aaatctacgt
     8041 cgctaacggc gacctgcaaa tgaacctcgc gcagatggaa cgtaacccga acgtgaaaat
     8101 cttctggccg gccaacgaca aaggcgagcg cagcgcgctg gccatccctt atgtcattgg
     8161 cctggtccag ggggcgccgc agagtgaaaa tggtaaaaag ctgattaact tcctgctgag
     8221 taaagaagcg cagactcgcg tcagcgaact ctcctgggga atgccggtac gcagcgacgt
     8281 gacgccgagc gacgaacatt acaaggccgc cactgccgcg ttagaaggcg tgcagagctg
     8341 gcagccaaat tgggatgacg tagccgtttc gctgtcggca gatattagcc gttggcacaa
     8401 agtgaccgaa agcgagtaag cctgatgctg atgaaaacga ctgccgttca cgcccctgca
     8461 tcgcagggga catcggggat agtcctcgac tcgctgcgtg ttgcgtatca cggcaacgtg
     8521 gtgcttaaac cgctctcttt gacgattgaa cctggcgaag tgctggcgct gattggccca
     8581 tcaggatctg gaaaaacgac ggtgctgcgt gcggtggcgg gctttgtgca gcctgcaggc
     8641 ggtcgtatcc tgattggcga tacggacgtc acccatctgc caccctataa acgcgggttg
     8701 gcgatggtgg tgcagaacta cgccttgttc ccgcatctga aagtggaaga caacgtcgct
     8761 tttggtctgc gtgcgcagaa gcagccaaag gcgctaatta atgagcgtgt cacgcaggcg
     8821 ctgaagacag ttggcatgag tgattacgcc acccgttatc cgcatcaact ttctggcggc
     8881 cagcagcaac gcgtggccat cgcccgcgcg attgccgtgc gcccgcgcgt gctgttgctg
     8941 gatgaaccac tgtcagcgct ggacgcacag attcgtcata atatggtgga agaaatcgcc
     9001 cgtcttcacc gtgagctgcc ggaactcact attctctacg tcacccacga tcaaacggaa
     9061 gcgctcaccc tggccgataa aatcggcatt atgaaggatg gctcgctgat tgctcacggc
     9121 gaaacccgcg cgttatatca ccatccgccc aatcgttttg ccgccgaatt cttaggtcgc
     9181 gccaatattc tctccgccat cgcgctgggg ataacggagg ttccggggct ggtggacgtc
     9241 agctgcggcg gtgcggtgat tcgcgcgttc agccagggca gccaccacgg ttacaacaaa
     9301 ctgctgtgca ttcgtcctca gcacctcagc ctaacgccgc gttcggccta cagcaaccgc
     9361 ttcaacgcca cactgcaatc ggtgcactgg caaggcgatt taacccatct gttgtgtgac
     9421 gttgctggcg aaacggtgcg gatggtgttg acgcatgtca atccgctgcc gcgcgtgggc
     9481 gacaagctgg cgctgtggtt cgaaccggat gatgcggtcc tgattgaggt ataaccatgt
     9541 cactcatttt acctctggaa aaaccggcgc ttaacctacg cccgctgctg tggctgttgc
     9601 tcccgttgct ggcgctggcg acgctgtttt tctggcctct gtcgctcatc gttgaacagg
     9661 cgctacgcgg tgccaatggc gagatcgggc tcgagacctt ccgccaggtg gtcgactcga
     9721 aacgctttgt cggcgcgttg ctgaacacgt tgcaaatcgc ctttttcgcc accgccggtt
     9781 gcctgctgct gggcagcgtg atgtcgctga ttctggtgtt tattcctttc cccggcagcg
     9841 agttgattgg tcgggtcgtc gatactttta ttgcgctgcc gaccttcctg attacgctgg
     9901 cgttcacctt tatttatggg tcagcgggtc tgctcaacgg tgcgctgatg agcctgtttg
     9961 cctttgagct accgccggtg gattttctct actcgatgca gggtgtcatt ctggcggaga
    10021 tcacggtgtt cactccgctg gtgatgcggc cactgatggc cgcgctgcgg caaattgata
    10081 aaagccagct agaggcagcc agcattctgg gggcacaccc gttacgggtg attgggcagg
    10141 tgattttccc ggcggcgcta ccggcgctga tggctagtgg cagcctgtgc ctgctgttga
    10201 ccactaacga gttcggcatc gtactgttta ttggcgcgaa aggggttaac accctgccga
    10261 tgatggttta cagcaaagcg attctggagt ccgactatac ggtcgcctgc atgattgcgt
    10321 tgattaacat tgtcttgtcg ctggggctgt tctccctcta tcgcctggcg gcatcgcgta
    10381 ccggcgtaag gagccagcca tgctaatttg gtcacctaaa ggacgcgcag cggcgggcgt
    10441 tgtggctagc gtactgttta tcgtgttctt tttcctgccg ctggcggtga ttctgatgtc
    10501 cagccttagc cagcggtgga acggtattct gccgagtggc ttcacgctga accactttgt
    10561 taacgctctg cacggtgcgg catgggatgc cctacttgcc agcctcacga ttggcttttg
    10621 cgccagcctg tttgcgctgc tttgcggcgt ttgggcggcg ctggcgttgc gtcaatatgg
    10681 ggtgaaaacg cagaaatggt taagtatggt gttctatctg ccgagtgcga ttccgtcagt
    10741 gtccgtgggc ctgggcattc tggttgcttt cagccagggg ccattgcaaa tgaacggcac
    10801 cctatggatt gtgctgacag cgcactttgt gctgatttcc gcctttacct tcagtaacgt
    10861 gtcgaccgga ctggcgcgca tttccgccga tattgaaaac gtcgcgtcga gtctgggggc
    10921 atcgccctgg tatcgtctgc gtcacgtgac gttgccgtta ttgatgccgt ggatggtgtc
    10981 agagctggcg ctgagtttat cgctctccat gggggagttg ggcgcgacgg tgatgattta
    11041 tccaccgggc tggacgacgc tgccggtagc tatctttagc ctgaccgacc gtggaaatat
    11101 cgccgacggc gcggcgctga ccattgtgct ggtggccatt acgctgctgc tgatgatgaa
    11161 gctggagcgc attgcaaaac ggttggggta gaaataaaac ggtaggccgg gtaggacata
    11221 gccgccaccc ggcaaaggaa ttacgggcga tacaccttca cattggcaaa cccctgctcg
    11281 cgcagataga gcgcctgcag gcgactcatt acgccgcgtt cgcaccatag cagccaggtt
    11341 ttgctctgat cgaggtcgcc aaatttagtg ctcagcttgt agaaaggcag cgaaacgacg
    11401 tcgacgcctt ccactttcag cggcttgtca tcctgctcat cgacagaacg gatatccaga
    11461 atcacatcgt tggcgccaaa accgctcacg gtttcaactt ccaccacctc ctgctgggtc
    11521 tgctgggcga tttcacgaat atcgacgttg ttcgcttctt ctaccacctt atcgagaata
    11581 ctgaagtcga aattttcttc ttcggcttca attttcgctt taatggcttt cactgtcgga
    11641 ctttttgaaa tcacgccaca gtattccggc atcgtacggg caaaatcttc cgtaccaatc
    11701 tggcgcgcca ggttgataat gtgctcttta tcgtaagaga tcagcgggcg caggatcagc
    11761 gtgtcagaca cgttatcgat caagcgcaag ttggttagcg tctggctgga cacctggccc
    11821 agcgcttcgc cggtcaccag cgcctgtacg ccgtaacgtt ccgccacttt cgacgccgcg
    11881 cgtaccatca tacgtttgag caccacgccc atctggccgt cgtcgacttt ctccagaatc
    11941 tcgccgacca ctggttcaaa gttaatcgcc acaaaacgca cgcgatggga gctgccaaag
    12001 cggttccaca ggtaatgcgc cacctggcga acgccgattt catgcgccgc gccgccgagg
    12061 ttaaagaagc agtagtgtac gcgacagccg cgacgcatca gcatatagct ggagacgctg
    12121 gagtcaaaac cgccggagat cagcgacagc acgtcttcct gggtgccaat cgggaaaccg
    12181 ccaatacctt cataacgccc tttgatcagc agcaggcgat catcttccac ttccagatgc
    12241 accgtcacat ccgggttagt gagcttcacg cgcgctgatt caatatgctg atttaatccg
    12301 ccgccaacat agcgctccac ttcaatggag ctaaactcat gcttaccgcg acgttttacc
    12361 cgcacgcaga aggttttgcc ttcaagctgt tcgcgatact gcgccaacgc tttctcgaaa
    12421 atgtcgtgca tatcggtgaa cggcacatct tcgacttcaa gaatatggtg aatccccggg
    12481 atgcgggtca gcgcgtcgcg aatcgccaga cgctggtttt catctttggc gcgaacttca
    12541 atgttatccc agtgacggac aaccgcgagg gtctcatcgt agtgctttaa aacgttacgg
    12601 atgttcccgg ttaaaatttt tataaagcgc aaacgcacag attggctttt gatagtgatt
    12661 tccgggaaca atttaatgat aaacttcatg gcggtaatgg ttctttagca agctatctaa
    12721 ggcttgtcgt ggagaaatag tacagcagcc catacctacg gctgcatcca ggcgcggaag
    12781 tatatcacca tcacggacat cttgcgcatt tccccttacc attgcgcgtt atttgcttat
    12841 cagtgcgagt ccgttaccat agacttgtgc tgccattaca gagagtcaaa cagtcatcat
    12901 gccgaagaaa aatgaggcgc ccgccagctt tgaaactgcg ctgagcgagc tggaacatat
    12961 tgttacccgc ctggaaagcg gcgatttgcc gctggaagac gcgctgaatg aattcgagcg
    13021 cggcgtacaa ctggcgcgtc aggggcaggc aaaactgcag caggcggaac agcgcgtgca
    13081 aattttgctg tctgataatg aagaggcttc acctgagcct tttatcgcgg ataatgagta
    13141 aatggacttt acgcagcagc tacaggcttg cgtaacgcaa gcgaatcagg cgctgagccg
    13201 ttttatcgcg ccactgccct ttcagaacac tcccgtggtc gaagccatgc agtatggcgc
    13261 attattaggc ggtaaacgcc tgcggccatt tctggtttac gccaccggtc aaatgtttgg
    13321 cgtcagtacg gcaacgctgg atgcgccagc tgcggcggtc gaatgcattc atgcctattc
    13381 gctgatccat gacgacctgc cagcaatgga cgatgacgat ttgcgtcgcg gcctgccgac
    13441 ttgccatatt aaatttggcg aagccaacgc aatcctggcg ggagacgcgt tgcaaacgct
    13501 ggcgtttacc attatcagcg acgcgccgat gccggaagtc gccgatcgcg atcgtatcgc
    13561 gatgatcgcc gaactggcaa acgccagcgg tatcgccggt atgtgcggcg gtcaggcatt
    13621 ggatctggcg gcagaaggcc agcggatcac tctggacgcg ctggaacgca ttcatcgcca
    13681 taagaccggc gcgctcattc gcgccgccgt tagacttggc gcgttgagcg cgggcgataa
    13741 aggacggaat actctgccga tacttgaccg ctatgcagag agtatcggcc ttgccttcca
    13801 ggttcaggat gacattctgg atgtggtggg cgatactgca acgttaggta aacgtcaggg
    13861 cgcagaccag cagcttggca aaagtaccta ccctgcactt ctgggtcttg agcaagcccg
    13921 gaataaagcc cgggacctga tagaggacgc ccgtcagtcg ttacatcagc tggccgcgca
    13981 atcactggac acctcggcac tggaagcgct agcgaactac ataatccagc gtgataaata
    14041 aaccccatat ccaatgagct tgcgatgagt tttgatatag ccaaataccc taccctggca
    14101 ttggtcgact ccacccagga gttacgactg ttaccgaaag agagtctgcc gaaactctgc
    14161 gacgagctac gccgctactt actcgacagc gtaagccgtt ccagcgggca tttcgcttcc
    14221 gggctgggca cggtagaact taccgtggcg ctgcattatg tctacaacac cccgtttgac
    14281 cagctaatct gggatgttgg acaccaggct tatccacata aaatccttac cggtcgtcgc
    14341 gacaaaatcg gcaccattcg ccagaaaggc ggtctgcacc cgttcccgtg gcgcggagaa
    14401 agcgaatacg atgtgctgag cgttgggcat tcctccacct ccatcagcgc cggtatcggt
    14461 attgccgtgg cggcggagaa agaaggcaaa gatcgccgca ccgtctgtgt gattggcgac
    14521 ggcgccatca ccgccggtat ggcgtttgaa gcaatgaatc acgcaggcga tatccgaccc
    14581 gacatgctgg tcattctgaa cgacaatgaa atgtcgattt cggaaaacgt cggcgcgctc
    14641 aacaaccatc tggcgcggct actttccggt aagctttact cttctctgcg cgaaggcgga
    14701 aaaaaagtct tctccggcgt accgccaatt aaagaactgc tcaagcgtac cgaagaacat
    14761 attaaaggca tggttgtgcc gggaacactg ttcgaagagc tgggctttaa ctacatcggg
    14821 ccggtcgatg gtcacgatgt catggggctt atcagcacat tgaagaacat gcgtgacctg
    14881 aaagggccgc agttcctgca tatcatgacc aaaaaaggcc gcggctatga gcccgcggaa
    14941 aaagatccga tcactttcca tgcggtgcct aaatttgatc cctccagcgg atgtttgccg
    15001 aaaagcagcg gcggtctgcc aggttattca aaaatcttcg gtgactggct gtgtgaaacc
    15061 gccgccaaag acagcaagct gatggcgatc accccggcaa tgcgcgaagg ttccggcatg
    15121 gtggaatttt cacgtaaatt cccggatcgc tattttgacg tcgctatcgc cgagcagcat
    15181 gccgtcacct tcgccgcagg tctggcgatt ggcggctata agcccgtcgt ggcgatctac
    15241 tctactttcc tgcaacgcgc ctacgatcag gtcatccatg acgtcgctat ccagaaactg
    15301 ccggtcatgt tcgccatcga tcgcgccggt atcgttggcg cggatgggca aacacaccaa
    15361 ggcgcgttcg atctctccta tctgcgctgc atcccggata tggtgatcat gacgccaagc
    15421 gacgagaacg aatgtcgcca gatgttattt accgggtatc actataacga cggcccgacg
    15481 gcagtacgtt atccacgcgg taatgcgcag ggcgtggcgc taaccccgct ggaaaaactg
    15541 cctattggta aaggtcttgt gaagcgtcat ggcgaaaaac tggcgattct gaactttggc
    15601 accttaatgc ctgaggcggc gaaagtcgcc gaagcgctga atgccacgct ggtcgacatg
    15661 cgctttgtta aaccgctgga cgacacgtta attctggaga tggccgcgca gcatgacgcg
    15721 ctggtgacgc tggaagaaaa cgccattatg ggcggcgctg gcagcggcgt aaacgaagtg
    15781 ctaatggccc atcgtaaacc tgtacctgtg ctgaatatcg gtcttccgga tttctttatc
    15841 ccgcaaggaa cgcaggaaga agcccgcgcg gaactggggc ttgacgccgc aggcattgaa
    15901 gccaaaatca aggcctggct ggcataatct cctctttgct cctgctatgc ttgaagagtg
    15961 acgggtataa caggagcgga gtcatgcaat acaacacgtt aggaaatacc gatcttcggg
    16021 tgtcccgcct ttgtctgggc tgtatgacat tcggcgagcc gagtcgcggc aatcacgcct
    16081 ggacgcttcc cgaagagagc agccgtccca tcatcaagcg cgcccttgag ggcggcatta
    16141 acttttttga taccgccaac agctactccg acggcagcag cgaagagatt gtcggtcgcg
    16201 cgctgcgtga ttttgcccgg cgcgacgagg tggtggtagc gacgaaagtc ttccatcgcg
    16261 tcggcgatct gccggaagga ttgtcccgcg cgcaaatcct gcgctctatt gacgatagcc
    16321 tcacccgtct gggaatggag tatgtcgata tcctgcaaat ccaccgctgg gattacacca
    16381 cgccgataga agaaactctg gaagcgctaa acgacgtggt aaaggcgggt aaagcccgct
    16441 atatcggcgc ttcctcaatg cacgcctcac aatttgccca ggcgctggcg ctacaaaaac
    16501 aacacggctg ggcgccgttt gtcactatgc aggatcacta taacctgatc taccgcgagg
    16561 aagagcgtga gatgctaccg ctgtgctggc aggaaggggt cgccgtgatt ccgtggagtc
    16621 cgctggcgcg cgggcgctta actcgcccct ggggagaaac cacggcccgg ctggcctcgg
    16681 atgacgtggg caaaaattta tacgatgaaa gcgataaaaa tgatgcgcaa atagcggaac
    16741 ggctggctgg cgtcagcgag gcgcttggcg caacgcgagc gcaggttgcg ctggcctggc
    16801 tgctcagcaa acgaggcgtc gccgcgccga ttatcggcgc ttcgcgtgaa gagcagttag
    16861 atgagttgct gaatgccgtt gatttaacgc tcaaaccgga gcagattgcc gaactcgaaa
    16921 caccgtacaa gcagcatccg gtggtgggat ttaaataatc tgccattgcc cgatggcgcg
    16981 gcgcttatcg ggcctgcgaa atcgacatat tgttcggagg caggccggat aaggcgttta
    17041 tgccgccatc cggcaaaccc tttaaataat accgagcggc cagtgatgac cgataaaata
    17101 cagtatgcca gcggatatca ccccggcgac gatatcatcg atcattatcc ccatgccgcc
    17161 gtgcacgttg cgatcaaacc aacggatcgg ccagggtttc cacatatcta gaatgcggaa
    17221 aataacgaac ccggcagcca cccattgcca gtccgtcgtc ggcaacgcca ttagcgttat
    17281 ccacataccg ataaattcat cccagacaat actgccgtgg tcgtgtacgc ccatatcttt
    17341 cgccgtctga tggcaaagat aaacgccaat gcagattcca aacatcacga ccagcgaata
    17401 aagctgccac ggcagaaacg tcatcagata ccagaagggg atcgccgcca gagagcccat
    17461 cgtacccggc accacggggc tcagcccgct gccaaagccg gtagcgagca gatgccacgg
    17521 attgcgcaaa ttcaggcgac ttttcgcaac atctttatgg cgtggcaaaa tggtcatatc
    17581 ctttccagtc gaaggtgaca ggcattccgt cacgtacaaa attcagccct tcaatatctg
    17641 cgctcatttg gcctatgcag gtaaagggaa cacccagttg accaatggcg acatccagcg
    17701 cgccacggtt cagttccggc accgtaaagc acaactcata gtcttcgccg ccggaaagcg
    17761 cccaacgcag ctcctgcccg tcatcaacat ggcgcatcat cgcatcggat tttggcaacg
    17821 catcaacatc cactcttgcc ccacagccgc tggccttgac gatatgcccc agatcggaaa
    17881 tcagaccatc ggaaagatcg atagccgcgc tggcgatgtc acgcagcgcc tggccgtgta
    17941 aaatacgcgg cgtcgggcgt aaatgccgtt gaattaaata gtgagcatcg gtctcctccg
    18001 acacctgtag ccggttttgc aaaaccgcca gcccggcagc gctgtcgccc ggcgtaccgg
    18061 tgacataaat ccagtcgccc ggcttcgcgc cagatcgctt gagcgcgcgc cctgccggga
    18121 tataaccgtg gatacccagc gtcatcgaca gcggtccacg cgtggtgtcg ccgccaatga
    18181 gctgcatatc gtagtaattc aatagcgcaa acaggctgtc gctaaaagcc tccagccacg
    18241 gctcatccac ttccggtagc gttaacgcca gcgttaacca ggccgggtcg gcccccatcg
    18301 cggccagatc gcttaaattc accgccaacg ctttataagc cagatcggca ggatcgatat
    18361 cagggaggaa gtggttgccc gccaccagcg tatcggtact gatcgccagg gtctgctttt
    18421 caggaatatt caggagcgcg caatcgtcgc caataccggt ttcaacatca agacgagagc
    18481 ttcttacacg gtcaaaataa cgggcaatca gggaaaactc gccacatgcc atacgttatg
    18541 cctcagcaga aaaaaagaaa aggccggaga cggcgggtat cgatcgcccg ctatctttcc
    18601 ggcctgtgaa tcactttttg ttgggacgaa tcaccggagc tgctttatcc agtacgccgt
    18661 tgacgaattt gtggctgtct tcagcgccaa aggttttcgc cagttcaatc gcttcgttga
    18721 tggccacttt ataaggcaca tcgctgcgtt ttgacagctc aaacaacgca atacgcagca
    18781 cggctttttc aacctgtccc agctcttcaa gcaggcggga cagatacggt ttcattaaac
    18841 catccaggta cgcgctgtta gtcgccaccc cggatagcag ttcacggaaa tagagaacgt
    18901 cgacgtcttt tacgtcctgt tccgccagga actggtattc aacatcagcg atgtcgttct
    18961 gggacaactg ccaggagtaa agcgcctgga cggcacactc acgggcgcgg tgacgagcag
    19021 caggtttcac ggaattcccc ttacaaaaaa tcaggcctta atggctttca atacattaat
    19081 catttcaagc gcggtcagcg cagcttctgc gcctttatta ccggcttttg taccagcacg
    19141 ttcgatggct tgttcaatac tctcggtggt cagaacacca aaggctaccg gcacgccgct
    19201 gtcctgggca acgcttgcca ggccattgct ggcgccgcct gccacatatt caaagtgcgc
    19261 agtccccccg cgaatcacgg ttcccagcgc aaccacggcg tcgtatttac cgcttttcgc
    19321 cagcgcttcg gtcgccagcg gcagttcata agcgccaggc acccacacta cggtaatatt
    19381 atcatctttt acctgaccaa tacgcgtcag ggcatcaacc gcgccatcca gcaggctgtc
    19441 gttgataaac tgattgaaac gcgcaatagt gatggcgaca cgagcgtcag gggctgcaac
    19501 gttagcttta ataatgttca tattctctct tccagggttc atttggcccc gcaggggggc
    19561 ggattttatc ataataattt gagcgctgct cccctttcga cgggagaact catgcgctca
    19621 ccatatgcag gcaaacatcc gggccgacat gacgtatttc gctgaaggta aattgcggcg
    19681 cgtcggcgag cttctcaagc cccggcaatt cgcataatcc ccgcgcctgg gttcccaaca
    19741 atttaggcgc gacatagaca atcagttcat ccaccagccc ggcttgcagc aacgcgcccg
    19801 ccagtcccgg tccggcctca acccatatgc tattaatctg ctgcctgcct aactgcatca
    19861 tcagcacaac cagatccaaa tgtccgttgt gcgccggcac gctgatagta cgaaccgaat
    19921 cgggccacgc gtggctatct tcctgggtac gcgcaatcca cgtttcgcca ggctgctgca
    19981 caatacgatg cgcaggcgtt acccggtttt ggctgtcgat aacaattcgc accggctggc
    20041 gcagattttc ctgcgggtaa gacgcctgtg tagaggcgtc taactccgcc caacgcaccg
    20101 tcaaggccgg atcgtcagcc aataccgtcg cgctactggt taaaatagcg tggctttgcg
    20161 cacgcaagcg ctgaacgtcg cgccgggcct gcggcgaggt gatccactgg ctttcgccgc
    20221 tggccatcgc cgtccgtcca tccacggagg cacccagttt aagctgaaga taagggaatc
    20281 cggtacgcat ccgtttgagg aagcctttat tgagcgcctc cgcttcactc atcattaacc
    20341 cgtggctgac cgcaataccc gcctgttgca ggcgatacag cccgcgcccg gcgacctgtg
    20401 ggttcgggtc ctgcatcgcg gcgaccacgc gcgcgacgcc agccgcaatc agcgcatcgc
    20461 aacatggcgg cgttcgccca tgatggctac agggttcaag cgtgacatag gcggttgcgc
    20521 ctttggcttt tgcgcccgcc atccgcagcg catggacctc ggcgtgcggc tctccggcgc
    20581 gatggtgata accttcgccg acgatgtcgc cattgttaac aatgacacag ccgacattag
    20641 ggttcgggtg agtggtgaaa cgtccacgct gcgccagttt gagcgctcgc gccatgtaaa
    20701 actcatcctg catggcttag tcctgtaggc gagcgatttc ttcgccaaag tctttgatat
    20761 cttcgaaact gcgatagacg gaggcaaagc gaatatacgc gactttatcg agttttttca
    20821 gctgctccat gaccaggttg ccaatcatct tgctgggaac ttcacgctcc ccagtggcac
    20881 gtaattgtga cttaatatgg ttcaatgcca tttcaacatc atctgcgctg acgggtcttt
    20941 tttccagcgc tctcaacatg ccgctacgca gcttatcctc attaaagggt tcgcgcacat
    21001 cgttgctttt tatcacgcgc ggcatgacca gttcagccac ttcaaaggtc gtaaagcgtt
    21061 cattacacac cagacactgc cgacggcggc gcacggacga gccctcgcct acaagacgag
    21121 agtcaatgac tttggtatct acggcgaaac aaaatgggca atgcatacgg cgtcctgacc
    21181 agatgattta ggaaatgcta ttttaccctg aactggcgcg acaacaaagg cggagcgctt
    21241 ttgagataaa ggatcggtgc ctttgtgcgt atagcgcact accattacgc tatcggacca
    21301 cgaaggaaat gatcgacatg acaagacgtt acctaagaat tctcctggtg ggaagtctct
    21361 tgagcctgac cgcctgcgcg ccgcagagcg aagttcgcca gatgcatcaa agcattagca
    21421 ccctgaataa agagatgacc caactgaatc aggaaacggt aaaaattacc caacaaaata
    21481 agctgaatgc ggattcaacc cgcggcgtct atttgttgcc tggcgccaat acgcctgccc
    21541 ggctggagag tcagatcggt acgctacgta tgacattgct ggaaattacg cctgtcgctg
    21601 acggcgctca cgcaacgtta cgcattcagg gcaagtcccg cgatccgcta ccggcattca
    21661 gcgctaccgt agagtacggg caaattcagg gcactacgga gaactatcag gaggtgaatg
    21721 cgcagagcct tctggtaaat gcgcccgcca gcttgctggc gcccagtgat gtcaatattc
    21781 cgttaccgtt gaaggggatc acaccggcgc agttaggctt cattcgcatc catgatattc
    21841 agcctgttaa tcaataaacg ttctggcgga gcgttttgtg cgctccgcaa catcctctgc
    21901 gcaacttttg ttgcccttct gacatttccg taatttatga cacggattgt taatattcat
    21961 gaaagatagt actgtcgccg cgcctaaagt gcgcaaacgt gaacgcaatc gattacgtaa
    22021 atgatagata tgtgaaacaa gacatatttt tgtgagcaat gatttttata ataggctccg
    22081 cagaaacacg aaatatttag aaacgcaaat tgcgttcttt tcactcccgc aagggatttc
    22141 aaacagtggc atacatatga aaaaaacttt actcgcagtc agcgcagcgc tggcgctcac
    22201 ctcatctttt actgctaacg cagcagaaaa tgatcagccg cagtatttgt ccgactggtg
    22261 gcaccagagc gtaaacgtgg taggcagcta ccatacccgt ttctcgccga aattgaacaa
    22321 cgacgtctat ctggaatatg aagcatttgc caaaaaagac tggtttgatt tctacggcta
    22381 tatcgatatt cccaaaacct ttgattgggg taacggcaac gataaaggta tctggtccga
    22441 cggttctccg ctgttcatgg aaatcgaacc gcgtttctcg attgataagc tgaccggcgc
    22501 agacctgagc tttggcccgt ttaaagagtg gtatttcgcc aacaactaca tctacgatat
    22561 gggcgataac aaagccagcc gccagagcac atggtatatg ggtctgggga ccgatatcga
    22621 caccggcctg ccgatgggtc tgtcgctgaa cgtgtatgcg aaatatcagt ggcaaaacta
    22681 cggcgcgtcc aatgaaaacg aatgggacgg ctaccgtttc aaagtgaaat acttcgtccc
    22741 catcaccgat ctgtggggcg gtaaactgag ctatatcggc tttaccaact ttgactgggg
    22801 atctgattta ggcgacgatc cgaaccgtac cagcaactcc atcgcttcca gccatatcct
    22861 ggcgctgaac tacgatcact ggcactactc ggtcgttgcg cgttacttcc ataacggcgg
    22921 acagtggcag aatggcgcca aactgaactg gggcgacggc gatttcagcg cgaaatctac
    22981 cggctggggc ggttacctgg tcgtgggtta caacttctaa acctgcaaaa aagccagagg
    23041 tcgtcctctg gcccgtttcg ggcgcatgct gccatgcggc ggcgagtcgc gcccacttca
    23101 cattacttcc ggcgatgcca ccagcctaaa aacagacctg tcgcaatccc gaccagcgtt
    23161 ggtgccgcca gatcgtgcca gatagtaatg ctcaactctg tgagcgtcat attgccgcct
    23221 ttgttgcaat ggcaacggtt cgcggctatc ctcaacttgt ctggggtcaa gttagccccc
    23281 gtaatgttgc cggtgaatac cgaacaatgt gcgggggttt tctctttcca gcgacaaggc
    23341 caccggggat caagcccccg caacattgcg cctcaccggg ttgccccggc ttaccgctga
    23401 ttctactctg ctcgccagta tcggcaggac ttaaaaacaa aaaaatccca accttgcgat
    23461 cggaattcca gtgacaatgt atgcgttaca ggacgtttgg ggctggcgac aaactccggg
    23521 gctgaaaaaa tgtcagattg catccgacct acgaaaacca ataattcatt tatattgcgg
    23581 attccgttgg gtggagtgga gcgaagcgta acctaacatt caacagcacc aacagctttg
    23641 tcagcagtct gcttatttct ttttgttcat catcgctttc agatcggcaa acgggttata
    23701 agtcgcctcg ccgacatctt tttgcgcatc ttccccggca atgaccgtcg aaccgtactg
    23761 atcggcttcg gtatatttag aatgctcatg atcgtggcag tagaggcaca atagctccca
    23821 gttactgccg tcttccgggt tattggtgtg gtcatgatcg atatgatgca ccgtcagctc
    23881 acgcagattt gaatacacaa actcacggga acaacgtccg cacacccacg gaaacagctt
    23941 cagcgctttt tcacgatagc cgctttccag gcgcgcgtag ttttttggga tgatagccat
    24001 aattaacagg tacctgaata atacaaaggg ttatgcgcag tttcccgcga agccgggctt
    24061 ttagcaatga ttctgtgcaa cttatatatc caggtaagga aggctatttc aggcaaactg
    24121 atgaccaatc aacccgtttt acaagcgttg gaggtatcgc tatcacatct tacggcattt
    24181 tttcgtgctc gactttacgc aaaaaatcac gcaaagaacg gtcgattgtt tcacgaaatc
    24241 gccggttaag cggagtaatt tgtaaacagc gatcgaggcg aaaacaccga tagtcttccc
    24301 gtctctcaca ccaggcaacc agtagccagt gctctcccca gaaaaacaat cccagaggtt
    24361 gtatatcccg cgaagagaga tgccccgctt catcacgata atgtagcgcc aacacctgct
    24421 gcgccgaaac agcctgatgg ataagatcaa acgcgctgcg cgaatgtgga gatgtaccca
    24481 aatccggagc gtaaatccgt gtctgctccg ctttacgacg gctctcttcc ggtaaaatag
    24541 ccaacacttt ttcctgggcg gattcaagct cgcgcgatag cgaatcgcca ccccaggttt
    24601 tcaataaccg tatagccacc atcagtgctt ccgattcacg atgggtaagc atcaagggcg
    24661 gcagatcaaa acccgccatt aaacggtatc cgctccccgc ttcaccttcg acaggcacac
    24721 cggataacga cagatcgcga atatcgcgat aaatcgtccg ttcagaaacc gcaagccgct
    24781 gtgccaacag cgctgccgtc gtcagtcgtc taccccgcaa aatttgcacg atctgaaaca
    24841 aacggtcagc gcgtctggtc atattgactc tctacattta gcaaatatca cgcaggttga
    24901 tgtaaaccta ttcggttacc ttcgctgtca ataaacaacg cgatggttcc aatgtcatct
    24961 ccgggaacca tgggttccag aacacacttg ccaccggcaa ggacgacacg ttcaatcgag
    25021 gctaacaaat cggcggtatg cagataaata acgactccct gcgcaactgg agcgacatca
    25081 tcctgcttta tcagcgctcc gccgggtccg ggttcagcat acgggaatac ggccaggtcc
    25141 gccccatcca tggtttcccg acgtaacgat atctgcatca cttgctcata aaaggcgatt
    25201 gcacgcgcca tatcagtaac tggaatttca aaccagttaa tcaagttttt catacatcct
    25261 cctgcgagtg tgggtaaatt catgaggagt gtatgacagg gctcctgaca gcatactgtc
    25321 agtaatgttt atcgtcatgg tacataaata aaaaatcccg atcgcatgac cgggattcag
    25381 ataacactta aatacgtgtt tacggcagaa tggacggctg atccgcccct tctttttcga
    25441 ctttctgctg cagcatatgc tcgcgcttca taccgagttt cagcgccagc gccgatgcga
    25501 catagataga agatgccgta ccaatagaga caccgatcag catcgtcagc gagaagcctt
    25561 ccagtaccgg accgccgaag aggtacagca tcagaattac cactaacgtc gtaccggagg
    25621 taatcaacgt acggtgtagc gtctgggtca gcgacacgtt aaagatttcg taaggcgtcc
    25681 cgcgacggat tttgcggaag ttttcacgaa tacggtcgga gaccacgata ctgtcgttca
    25741 gcgagtaacc gatcaccgac atcaacgatg ccacaatggt caggtcaatc tcaatatgga
    25801 aaagcgacag tatccccagc gtaatgatca cgtcgtgcgc cagcgcgatg accacccctg
    25861 ccgccagtcg ccactcaaag cggaaaccga cataaacgag gatagagatc aacgccacca
    25921 gcagcgccat ggcgccggtt tgcgccagat cggcgcccac gcttggcccc acgaattcaa
    25981 tacgcttcac ggccgcgttc tggttggtgg cttcattaat gatcgtcacc actttgctac
    26041 ccagtacctg accgccggtt tcaccttcgg ttggcggcat acgcaccata atgtcgtgac
    26101 tgctgccaaa gttctgcaac tgcggctctt catagcccgc tttttgcagc gcttcgcgca
    26161 tcacgtccat ttcagccggt ttttccagcg tgatttcaat taccgtacca ccggtgaaat
    26221 ccagccccca gttaaacccg cgtacgccca taatgacaat ggccgcgatc agcaacagcc
    26281 cggagatgcc gaatgcccag aagtcccagc gcataaagtc atagacttta cggccgtggt
    26341 ttagttgttc aacagtgtat tcctgtgcca catcgcactc ctcagattga cagcttagtg
    26401 acgcgcttgc cgccatatag caggtttacg atagcacgcg taccgataat cgcggtaaac
    26461 atcgacgtcg ccacaccgat accggtcgta atcgcgaacc ctttaattgc cccggtaccg
    26521 acagcataca gaatgatgac tttaatcagc gtcgtgatgt tcgcatcgaa gatggaactg
    26581 aacgcgccgg catagccttc gtttatcgcc tgctgtaccg tgcggccatt actcaactct
    26641 tctttgatac gttcgttaat cagaacgttg gcgtcgaccg ccaccgcaag ggttaacacg
    26701 atacccgcaa tccccggcat actgagcgtt gcccccggca acagcgacat gataccgaca
    26761 atcaacacca ggttagccac taacgcgctg gtcgcaatca gaccaaactt cttatagaag
    26821 aagatcatga acaggatgga gaccaccaga ccggccagac aggcttccag gccctgcttg
    26881 atgttctgca tacccagagt cgggccaatg gtgcgctctt caacgatctg aatcggcgca
    26941 atcagggcac ccgcacgcag caacaacgag agctgacgcg cttcgttcgg gttgctgata
    27001 ccggtaatac ggaagctgtt acccagccga gactggatgt tggcaatgtt aatcacctct
    27061 tcctgtttca ccagtacggc gcgaccgtta gcgtctttct taccgctgtc tttatactcc
    27121 acaaacaggg tcgccatcgg tttgccgata ttgtccttag tgaagttaga catgatattg
    27181 ccgcctgcgc tatccagcga gatgttaacc tgcggttggt tatattcatc ctggctggac
    27241 gtcgagtcgg tgatatggtc gccggtgagg atcacgcgtt tgtacaatac caccggctga
    27301 ccttcgcggg tctgtttcac ttcggaatcg cccggtacgc gcccggcagc agcggcggcc
    27361 tggtcaacgt tggtattcac cagacggaat tccagcgtcg cggtcgcgcc gagaatttct
    27421 ttcgcgcgag cggtatcctg gatacccggc agctcaacca caatacggtc tgcgccctgg
    27481 cgttgtacga caggctccgc gacgcccagt tggttaacac ggttacgcag aatattaatg
    27541 ttctgctgaa cggcgtattc acgcgcttcg ctcaggcgcg catcggtcat taccgcgcga
    27601 agttgattgc cgctctggct ggaaatcacc aggtcacgat gacgcggcgt cagataggcg
    27661 atcgcctcat cacgcgcttt gctgtcacgg aacgtgatgc tcagcccata attattttct
    27721 ttacgaacgg tggtataagg aatgcctttt tcacgcagat cgctgcgcag gctatcgata
    27781 ttttgttcct ggagtttacc taacgcggta tccatatcca cttccatcag gaagtgaacg
    27841 ccgccgcgca gatcaagacc gagcttcatc ggatcggcgt gaatagccgc caaccagcgc
    27901 ggcgtagccg gcgcaaggtt aagcgccacg acatatttat cccccagcac gctcatcagc
    27961 gcttcacggg cgcgtagctg ggtatcggtg gtgtcgaagc gcgcaagaat agcgccctct
    28021 tccagtgcca cagacttagc gggaattttt tcttcttgta acgttttctg gacctggatc
    28081 agcgtttgct cactggcggc gacgccgcgc acgccagtga tttgaacagc cggatcctca
    28141 ccatacaggt tgggaagtgc gtaaagcagg ccgacgataa tcacgacgac cagcatgatg
    28201 tacttccaca aaggataacg gtttaacacg gcagttccct ttgggaaaac gaaatattac
    28261 agcgccttca tggtgccttt cggcagaacg gcagctacga agtcacgttt gataaccact
    28321 tccgtggtgt cattcagcgc gatggcaatg tagccggctt ccgctacttt ggtcactcga
    28381 ccaaccagac cgccattcgt cagaacttca tcacctttcg caatggagtc catcagcttt
    28441 ttgtgctctt tggtgcgctt ctgctgcggg cgcaggatca tgaaatagaa aatcagacca
    28501 aacaccacca gcattaaaat cagagacatc gggctgccct gcgccggagc acctgttgcc
    28561 gctaccgcat cagaaataaa aaagctcatt caaattccct cattattaaa attaatcaac
    28621 gttcaaaggt ggaacgggtc gcccctgacg ttggtaaaac tcggttacga agctctctaa
    28681 tttaccctct tcaatagcct tgcgtaaacc cgccatcaaa cgctggtagt aacgcaagtt
    28741 atgaatggta ttgagacgcg cacctaatat ttcgttgcaa cggtcgagat gatgcaagta
    28801 agcgcgtgaa taattgcgac aggtgtagca atcgcactcg gcgtcaagcg ggctgatgtc
    28861 gcttttatgc tttgcattac gaatcttcac cacgccgtcg gtcacaaaca gatgaccatt
    28921 acgggcattt cgcgttggca tgacacagtc aaacatatca ataccgcgac gcaccccttc
    28981 caccagatct tccggtttac ccacgcccat caggtaacgc ggtttgtcag ccgggatctg
    29041 cgggcaaacg tgctccagaa tgcggtgcat atctgctttc ggctcaccga cagccaaacc
    29101 gccgacagcg tagccatcaa agccaatctc taccagacct ttcaccgaga tatcgcgtaa
    29161 atcttcgtaa acgctgccct gaatgatgcc aaaaagcgca ttcttattgc caaggctatc
    29221 aaaacggtcg cggctacgct tcgcccaacg caacgacatc tccatcgagc gtttagcata
    29281 gtcccagtct gccgggtacg gcgtacattc atcaaagatc atcacgatat cggaaccgag
    29341 atcgtactgg atctccatcg acttttccgg atcgaggaaa atcggatcgc cgttgatcgg
    29401 gttacggaag tgcacgcctt gctcggtaat cttacgaata tcgccgaggc tgaagacctg
    29461 gaagccgccg gaatcggtga gaatcggccc tttccactgc atgaaatcgt gcaggtcgcc
    29521 gtgcagcttc atgatttcct gacccgggcg cagccacagg tggaaagtgt tgccgagaat
    29581 aatctgcgcg ccggtcgctt ccacttcttc cggcgtcatg ccttttaccg taccgtaagt
    29641 acccacaggc ataaaagcag gcgtttccac tacgccacga tcaaacacca gacgaccgcg
    29701 acgcgcgcga ccatcggtgg tatctaactc aaatttcatt atcactcctg cgtcagaaaa
    29761 acagtccgac gtttaacgac tcgctacgga atgattccat agctaataaa ttcccgaagg
    29821 cgtcatcggc gcagccagtt tggagtcggc cagcgcacaa ccaccggagc gtacacgcag
    29881 tacgtgagga tggcgagcac tgcccggcgt caaaatggca agtgagatag ccttcttacg
    29941 gacgctcaga aatagcctgc ggattgcacg tgataaacat cgcgtccccg tagctaaaaa
    30001 agcgatattt ttgttctacc gcagtcttat aggcattcat ggtgtgttga taaccggcaa
    30061 atgcggaaac cagcataatc aacgtcgatt ccggcagatg gaagttggtg atcagcgcat
    30121 caatcacttt gtattgataa cctggataaa taaagatttg cgtatcgccg aagaatggct
    30181 ctatcaaatc gctttttgcc gcctgcgccg cgctctccag tgagcgtacc gaggtcgtgc
    30241 cgacggcgat aacccggttg ccgcgcgctt tcgccgccag caccgcgtcg accacctctt
    30301 gcggcacctc agcatattcg gagtgcatga tgtgatcttc aatggtatcg acacgcactg
    30361 gctggaaagt gcccgcgccg acgtgtagcg taacaaacgc catttcgaca cctttctcac
    30421 gaagcgccgc cagcagcggc tcatcaaagt gcagccccgc ggtcggcgcg gcgacggcgc
    30481 ccggtttttc actgtaaacc gtctgataca gttcgcggtc ggcgtcctcg tccggacggt
    30541 cgatatacgg cggcaacggc atatggccga tggcgttgag aatatccagc accggacgcg
    30601 ggtcattaaa ctcaacttca aacagagcgc cgtgacgcgc ggtcatggtc gcgtgaatac
    30661 tttcgtcatc gcccagtagc agttccgtgc ccggttttgg cgctttagaa gcgcgaatat
    30721 gcgccaggat gcgtttatca tcgagcatac gttcgaccag cacttctatc ttgccgccgc
    30781 tggctttacg gccaaacagg cgcgccggga tcacgcgggt attattgaag accagcaaat
    30841 cgccagggtt gagcttatcg agcagatcgg tgaaagtacc gtgcgtcagc gcgcccgtcg
    30901 gcccctctaa tgacagcaaa cggcagcgac tgcgttccgg ctgtgggtag tgggcaatca
    30961 aggattcggg tagttcaaag gaaaaatcgg taacgcgcat gactctgact cagactaaaa
    31021 taagaggcgg gtagtctagt gccggggcgt tcccgctgca accgttaccc gctttttgga
    31081 cagagaatca ataatgaatt ttcttgctca cctgcatctg gcgcaccttg ccgacagctc
    31141 gctttccggt aatctgctgg ccgattttgt ccgcggtaac ccggcaacgc attatcctcc
    31201 tgacgtggta gagggtattt atatgcatcg gcgtattgac gtcatgaccg acaacctgcc
    31261 ggaagttcgt gaggcgcgag agtggttccg ccatgaaacg cggcgcgtgg cgcccattac
    31321 gctggacgtc atgtgggatc attttttatc gcgccactgg acgcaaatct ctcccgattt
    31381 tccacttcag gcgtttgtcg gctacgccca tgcgcaggtc gcgacgattc tgcccgactc
    31441 cccgccgcgc tttgtcaacc tgaatgatta tctttggtca gaaaaatggt tagagcggta
    31501 tcgcgatatg gatttcattc aaaacgtgct gaatggcatg gcgaatcgcc gtccccggct
    31561 ggatgccttg cgtgattcct ggtacgatct ggacgcgcac tacgacgcgt tagaagagcg
    31621 cttctggcat ttttatccgc gtatgatggc acaggccgcc cgcaaagcgc tgtgacggcc
    31681 tgatagcgag ggcgtgcgtc agatccgccg ttggcagaaa gatcgttcgc tgtcataaag
    31741 gagtcatcat tacgatttat aatgacccga tcgataggca aaagctgtct cattgattgt
    31801 caagaccgca ttgttttgtc gcttcgccct ccctatactg cccgcgttgc gttctaaaac
    31861 ccttaatatt gcaggagaat tattatggta ctggttactc gtcaggcccc ggatttcacc
    31921 gctgcggcgg tactgggtag cggtgagatt gttgataaat tcaacttcaa acagcacacc
    31981 aatggtaaaa cgaccgttct gttcttctgg ccgatggact tcacttttgt ttgcccgtct
    32041 gagctgatcg ccttcgataa acgttatgaa gaattccaga agcgcggcgt tgaagtggtc
    32101 ggcgtttctt tcgactctga gttcgtccac aacgcatggc gtaacacccc tgtcgataaa
    32161 ggcggcattg gcccggtgaa atacgcaatg gtcgctgacg tgaagcgtga aattcagaaa
    32221 gcttacggta tcgaacatcc ggacgaaggc gttgcgctgc gcggctcttt cctgattgac
    32281 gcaaacggta ttgttcgcca ccaggtcgta aacgatctgc cgctgggtcg taacatcgac
    32341 gaaatgctgc gtatggtcga cgcgctgcag ttccacgaag agcacggcga tgtctgcccg
    32401 gcgcagtggg aaaaaggcaa agaaggcatg aacgcctctc cggacggcgt ggctaaatac
    32461 ctggctgaga atatttccag cctgtaagtc agtgcattga taaaaggctc gcgaatgcga
    32521 gcctttttta tgcgtgaggt attatgaacc acctcgcctc aacgattcat ccataccgtc
    32581 gcggaaatcg cgggtaaact aagtcttccc tcgcggatgt caccgcttcc cgttttacat
    32641 tgccatccgg ccacgttcag caacggcaac gcttccagcg ccacttcaca ggcctcgccc
    32701 cggttaatcg ccaccagcgc ccgctgctgc tgataaactc gcacgaatac cactacgtca
    32761 ccttcggcat acagcgcctg gcatccgcca cgacgcagcg ccagactgct ctggcgcagt
    32821 ttcgccatac gctggtacag cgccagcaag ttgccgtcct gcttgcgttc atcccatggg
    32881 aacggtttgc ggcacatggg gtcatttgcg ccgtccacgc cgacttcatc gccgtaataa
    32941 atacatggca cgccgggcca ggtaaacagc cagaccaccg ccagcggcag gcgcgccgcg
    33001 tctttaccca gcagggtttt aaagcgcgca gtatcatggc tgtcgagttg attaaacatg
    33061 cgcagttgct gctggtgcga taatccggcg cggtagttat ccatccacgc gatacaggtc
    33121 cgggcatcaa tatgctgtgg ttcgtaagcg atatcagtat tggcgagaaa tccccacagc
    33181 gggaaggtga agccgcgata attcatggcg gcatcttccg catcggcctg tagccactgc
    33241 cgcgcatcgc tgaaatgttc ccccacaata taggcttcag gctgcgcctc ttttgccgcc
    33301 cgggtaatgc cggcgacgtg ctgcaaattg tggcgcgccc cgcccgcctc gcccagcata
    33361 tgtacgacat ccagccgcca gccgtccata ttccacggtg cctttagcca gtgacgaacg
    33421 atactgtcct caccgcgata gatctcatcc accagcgttt ctgattgata atcgagtttc
    33481 ggcaggctcg gataacccag ccagtccagc gccacgcctt gtggtgaaaa ggagtaccag
    33541 tcgcgccacg gcgagtccgg gtgatggcac gcgccgccag tgctgcggtt atgcctgtca
    33601 aaccacgcat gcgagtcgcc gctatggtta aacacgccat ccagcaccag cctcatgccc
    33661 tgtgcttgcg tttcacgccg caggcgtagc agcgcccgat cgccgccaaa ttgcggatcg
    33721 acatggcgat aatcttccgt gtcgtactta tggacgctcg gcgcggtaaa taccggattc
    33781 agatatagcg ctgtgacgcc cagttttttc agatacggca gcttctcaca aatgccattc
    33841 agacagccgc cgtaaaaggt ggaaccgccc gcctgggggg ttaaaggatc gtcccagtcg
    33901 cgcagcacaa tctcctgacc cgcggcatga tggtaataca ctcggtcctg atcggcttca
    33961 cgcgtcgcgc tgcgggcaaa acgatccggg aagatctgat aaaaaatttg atcggcgacc
    34021 cactgcgggc cgctatccgg cacatcaacc gcaaattgtt ccagacgcgc gggtggaaag
    34081 cagctaaatc cctgcggcgt aaaccatcgc tggcggtcat gccaaagcaa tttaaagctg
    34141 taacggcgac ggggctgccc taacgcgata ttgagcgtcg ctcgccacgc cgtcacgccc
    34201 ggctgcggct ggcggcgctg tttgcgcatc gccagtgaga tttcttcgtt atcgaattct
    34261 gagcgcaacg tcacgcgaga cggcggattt tctccgctca gccacagcgt aatggttaat
    34321 ttatcgttat gttgcttaac aaacggggca accggtaagt gccaggcatt caacatctcg
    34381 tatcccctct actaaaaatg gggccacctt gccacagaga tttaaaggat aactcatcat
    34441 ccgggggttt attaggggag gagactccag gaggagaaac ggctccgctt atccggcctg
    34501 ccgttgcctg cagaccggat aaggcagaga aaaacgacta cgcctgcgcc aattgacggt
    34561 cgcgacggcg tttaaatatc cagccaatca acagcagaac tatccaggcg aagcccacat
    34621 acagtgagat gcgggtattc ggatggtagc cgataagcgc aataatgaag accaggaaaa
    34681 tcagacccgc tatcgtcgtt acgacaccgc ccggcacctt aaacttcagc gcttttacct
    34741 cttccggcgg taaacgacga cggaaggcga tttgcgacag caggatcata atccataccc
    34801 ataccgtcgc aaacgtcacc agcgaggcaa tcaccaggaa gacgttttcc ggcatgatgt
    34861 agttcaggta aaccgcaaac agcagcgcaa tcgtcatcac cagcacagtg acccacggaa
    34921 taccacggcg tgacgttttg gcaaagactt tcggcgcgct cccctgctcc gccataccat
    34981 gcagcatacg gcctacgcca aacacatcgg agttgatagc ggaaagcgag gcggtcaata
    35041 ccacaaagtt cagaatgctg gcggcaaagg taatccccat atgctggaac gtcagcacaa
    35101 atgggctgcc gtttgtgccg acctgattcc acggatagat agacataatg acgaacagcg
    35161 tgccgacata aaataccagg atacgcatcg gtactgagtt aatggcgcgc ggaatggatt
    35221 tctccgggtc tttcgcttcc ccggcggtga taccgataat ctcaatcccg ccgtaagcga
    35281 acatcaccat ttgcagcgac atgatcattc ccagccagcc attgctgaag aagccgccgt
    35341 tgctccacag gttatgaatg ccagtcggct gcccgccgtt gccaattccc cacacaatga
    35401 tgccgatacc cgcgacaatc atgataataa tggtggcgac tttgaagaag gagaaccaaa
    35461 actccagctc gccgaacatc ttgacgctca tcaggttgat ggcgcaaatg atcagcacca
    35521 cgctaagcac ccaaatccag tgcggcacgg cggggaacca gacccccatg taaatgccga
    35581 acgcggtcac gtcagcaatg gcgacgatca ggatctcaaa acagtaggtc cagccggtaa
    35641 tgtagcccgc aagcgggccg aggttttcct gcgcatagcg cgaaaatgag ctggcggcag
    35701 ggttgtgaac ggacatttcc cccaatgcgc gcataatgat atatgccgcg accccgccaa
    35761 taatataggc caacagcacg ctcggccccg ccattttgat ggcgtccgcc gagccgtaaa
    35821 acaggccggt gccgattgcc gaacctaatg ccataaagcg aatgtgccgg gtgctcagcc
    35881 cacgctttag cttattattg ctttccatca atttctgacc tatcaaca
//
LOCUS       DAJVBX010000016        35670 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.016, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000016 DAJVBX010000000
VERSION     DAJVBX010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 35670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35670
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.016"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            368..703
                     /gene="eutS"
                     /locus_tag="OPV72_000745"
     CDS             368..703
                     /gene="eutS"
                     /locus_tag="OPV72_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutS"
                     /protein_id="HCR9913119.1"
                     /translation="MNKERIIQEFVPGKQVTLAHLIAHPGEELAKKIGVPDAGAIGIM
                     TLTPGETAMIAGDLAMKAADVHIGFLDRFSGALVIYGTVGAVEEALLQTVSGLGRLLN
                     FTLCELTKS"
     gene            716..1195
                     /gene="eutP"
                     /locus_tag="OPV72_000746"
     CDS             716..1195
                     /gene="eutP"
                     /locus_tag="OPV72_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization acetate kinase EutP"
                     /protein_id="HCR9913120.1"
                     /translation="MKRIAFVGAVGAGKTTLFNALRGNYSLARKTQAVEFNDHGDIDT
                     PGEYFSHPRWYHALITTLQDVDTLIYVHAANDKESRLPAGLLDVGTRKRHIAVISKTD
                     MPDADVAATRQLLCEIGFREPIFELNGHDPQSVRQLVDYLAALSEQEEEAGEKTYHS"
     gene            1173..1862
                     /gene="eutQ"
                     /locus_tag="OPV72_000747"
     CDS             1173..1862
                     /gene="eutQ"
                     /locus_tag="OPV72_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization acetate kinase EutQ"
                     /protein_id="HCR9913121.1"
                     /translation="MKKLITANDIRAAHARGEQAMSVVLRASIITPEAREVAELLGFT
                     ITECDESVPASTSAQACKSESQRIREAIIAQRPEGQFTESLVAQLMEKVLKEKQSLEL
                     GTMQPSFTSVTGKGGVKVIDGSSVKFGRFDGAEPHCVGLTDLVTEQDGSSMAAGFMQW
                     DNAFFPWTLNYDEIDMVLEGELHVRHEGETMIAKAGDVMFIPKGSSIEFGTPTSVRFL
                     YVAWPANWQSV"
     gene            1859..2656
                     /gene="eutT"
                     /locus_tag="OPV72_000748"
     CDS             1859..2656
                     /gene="eutT"
                     /locus_tag="OPV72_000748"
                     /EC_number="2.5.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization cob(I)yrinic acid
                     a,c-diamide adenosyltransferase EutT"
                     /protein_id="HCR9913122.1"
                     /translation="MNDFITETWLRANHTLSEGSEIHLPADARLTPSARELLESRRLR
                     IKFLDQQGRLFVDDDEQQPVHGLTSSDTHPQACCELCRQPVVKKPDTLTHLTADKMVA
                     KSDPRLGFRAALDSAIALTVWLQIELAEPWQPWLFDIRSRLGNIMRADAIDEPLAAQS
                     IVGLNEDELHRLSHQPLRYLDHDHLVPEASHGRDAALLNLLRTKVRETETLAAQVFIT
                     RSFEVLRPDILQALNRLSSTVYVMMILSVAKHPLTVAQIQQRLGEKP"
     gene            2653..3669
                     /gene="pta"
                     /locus_tag="OPV72_000749"
     CDS             2653..3669
                     /gene="pta"
                     /locus_tag="OPV72_000749"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HCR9913123.1"
                     /translation="MIIERARELAVRAPARVVFPDALDERVLKAAHYLQQCGLARPVL
                     VASPFALRQFALSHRMAMDGIQVIDPHSNLSMRQRFAQRWLARAGEKTPPDAVEKLSD
                     PLMFAAAMVSAGEADVCIAGNLSSTANVLRAGLRVIGLQPGCKTLSSIFLMLPQYAGP
                     ALGFADCSVVPQPTAAQLADIAIASADTWRAITGEEPRVAMLSFSSNGSARHPNVANV
                     QQATEFVRERAPQLLVDGELQFDAAFVPEVAAQKAPDSPLQGRANVMIFPSLEAGNIG
                     YKIAQRLGGYRAVGPLIQGLAAPLHDLSRGCSVQEIIELALVAAVPRQADVSRERSLH
                     TLVE"
     gene            3710..3994
                     /gene="eutM"
                     /locus_tag="OPV72_000750"
                     /pseudo
     CDS             3710..3994
                     /gene="eutM"
                     /locus_tag="OPV72_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013365323.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutM"
     gene            4112..4399
                     /gene="eutN"
                     /locus_tag="OPV72_000751"
     CDS             4112..4399
                     /gene="eutN"
                     /locus_tag="OPV72_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutN"
                     /protein_id="HCR9913124.1"
                     /translation="MKLAVVTGQIVCTVRHQGLAHDKLLMVEMIDAQGNPDGQCAVAI
                     DSIGAGTGEWVLLVSGSSARQAHRSELSPVDLCVIGIVDEVVAGGKVVFHK"
     gene            4411..5814
                     /locus_tag="OPV72_000752"
     CDS             4411..5814
                     /locus_tag="OPV72_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase EutE"
                     /protein_id="HCR9913125.1"
                     /translation="MNQQDIEQVVKAVLLKMKDSSQPASTVHEMGVFASLDDEVAAAK
                     RAQQGLKSVAMRQLAIHAIREAGEKHARELAELAVSETGMGRVDDKFAKNVAQARGTP
                     GVECLSPQVLTGDNGLTLIENAPWGVVASVTPSTNPAATVINNAISLIAAGNSVVFAP
                     HPAAKKVSQRAITLLNQAVVAAGGPENLLVTVANPDIETAQRLFKYPGIGLLVVTGGE
                     AVVDAARKHTNKRLIAAGAGNPPVVVDETADLPRAAQSIVKGASFDNNIICADEKVLI
                     VVDSVADELMRLMEGQHAVKLTAAQAEQLQPVLLKNIDERGKGTVSRDWVGRDAGKIA
                     AAIGLNVPDQTRLLFVETPANHPFAVTEMMMPVLPVVRVANVEDAIALAVQLEGGCHH
                     TAAMHSRNIDNMNQMANAIDTSIFVKNGPCIAGLGLGGEGWTTMTITTPTGEGVTSAR
                     TFVRLRRCVLVDAFRIV"
     gene            5825..6664
                     /gene="eutJ"
                     /locus_tag="OPV72_000753"
     CDS             5825..6664
                     /gene="eutJ"
                     /locus_tag="OPV72_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutJ"
                     /protein_id="HCR9913126.1"
                     /translation="MAHDEQLWLTPRLQKAAALCNQTPAASDTPLWLGVDLGTCDVVS
                     MVVDGNAQPVAVCLDWADVVRDGIVWDFFGAVTLVRRHLDTLEQQLGCRFTHAATSFP
                     PGTDPRISINVLESAGLEVSHVLDEPTAVADLLALDNAGVVDIGGGTTGIAIVKQGKV
                     TYSADEATGGHHISLTLAGNRRIPLEEAEQYKRSNAQEIWPVVKPVYEKMAEIVARHI
                     EGQGIADLWLAGGSCMQPGVEALFRQRFPELQVHLPQHSLFMTPLAIANSGRAKAKGL
                     YAS"
     gene            6654..7841
                     /gene="eutG"
                     /locus_tag="OPV72_000754"
     CDS             6654..7841
                     /gene="eutG"
                     /locus_tag="OPV72_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization ethanol dehydrogenase
                     EutG"
                     /protein_id="HCR9913127.1"
                     /translation="MQAELQTALFQAFNTLNLQRVKTFSVPPVTLCGLGALGACGQEA
                     QARGVSHLFVMVDSFLHQAGMTAPLARSLAMKGVAMTVWPCPPGEPCITDVCAAVAQL
                     REAACDGVVAFGGGSVLDAAKAVALLVTNPDQTLSAMTERSTLRPRLPLIAVPTTAGT
                     GSETTNVTVIIDAVSGRKQVLAHASLMPDVAILDAAVTEGVPPNVTAMTGIDALTHAI
                     EAYSALNATPFTDSLAIGAIAMIGKSLPKAVGYGQDLAARENMLLASCMAGMAFSSAG
                     LGLCHAMAHQPGAALHIPHGQANAMLLPTVMGFNRMVCRERFSQIGRALTNKKSDDRD
                     AIAAVCELIAEVGQSKRLADAGAKPEHYSAWAQAALEDICLRSNPRTATQAQIIDLYA
                     AAG"
     gene            7960..9186
                     /gene="eutH"
                     /locus_tag="OPV72_000755"
     CDS             7960..9186
                     /gene="eutH"
                     /locus_tag="OPV72_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HCR9913128.1"
                     /translation="MGINEIIMYIMMFFMLIAAVDRILSQFGGSARFLGKFGKSIEES
                     GGQFEEGFMAMGALGLAMVGMTALAPVLAHVLGPVIIPVYEMLGANPSMFAGTLLACD
                     MGGFFLAKELAGGDVAAWLYSGLILGSMMGPTIVFSIPVALGIIEPSDRRYLALGVLA
                     GIVTIPIGCIAGGLIAMYSGVQINGQPVEFTFALILMNMIPVLIVAVLVALGLKFIPE
                     KMINGFQIFAKFLVALITIGLAAAVVKFLLGWELIPGLDPIFMAPGDKPGEVMRAIEV
                     IGSISCVLLGAYPMVLLLTRWFEKPLMNVGKLLNVNNIAAAGMVATLANNIPMFGMMK
                     QMDTRGKVINCAFAVSAAFALVDHLGFAAANMNAMIFPMIVGKLIGGVTAIGVAMMLV
                     PKDDAAQVKTEAEAQS"
     gene            9183..10586
                     /gene="eutA"
                     /locus_tag="OPV72_000756"
     CDS             9183..10586
                     /gene="eutA"
                     /locus_tag="OPV72_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase reactivating factor
                     EutA"
                     /protein_id="HCR9913129.1"
                     /translation="MNTRQLLSVGIDIGTTTTQVIFSRLELVNRAAVSQVPRYEFIKR
                     DISWQSPVFFTPVDKQGGLKEAELKALILAQYQAAGIAPESVDSGAIIITGESAKTRN
                     ARPAVMALSQSLGDFVVASAGPHLESVIAGYGAGAQSLSEQRMCRVLNIDIGGGTSNY
                     ALFDAGKVSGTACLNVGGRLLETDAQGRVVYAHQPGQMIIDEVFGSGTDARALAAAQL
                     GQVARRMADLIVEVITGALSPLAQSLMQTGLLPADITPEVITLSGGVGECYRNQPADP
                     FCFSDIGPLLATALHEHPRLREMNVQFPAQTVRATVIGAGAHTLSLSGSTIWLEDVQL
                     PLRNLPVAIPQDDADLVNAWRQALLQLDLDPQTDAYVLALPSTLPVRYAALLTVINAL
                     TAFVARYPNPHPLLVVAEQDFGKALGMLLRPQLPQLPLAVIDEVVVRAGDYIDIGTPL
                     FGGSVVPVTVKSLAFPS"
     gene            10598..11959
                     /gene="eutB"
                     /locus_tag="OPV72_000757"
     CDS             10598..11959
                     /gene="eutB"
                     /locus_tag="OPV72_000757"
                     /EC_number="4.3.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit alpha"
                     /protein_id="HCR9913130.1"
                     /translation="MKLKTTLFGNVYQFKDVKEVLAKANELRSGDVLAGVAAASSQER
                     VAAKQVLSEMTVADIRNNPVIAYEEDCVTRLIQDDVNETAYNRIKNWSISELREYVLS
                     DETSVDDIAFTRKGLTSEVVAAVAKICSNADLIYGGKKMPVIKKANTTIGIPGTFSCR
                     LQPNDTRDDVQSIAAQIYEGLSFGAGDAVIGVNPVTDDVENLTRVLDTVYGVIDKFNI
                     PTQGCVLAHVTTQIEAIRRGAPGGLIFQSICGSEKGLKEFGVELAMLDEARAVGAEFN
                     RIAGENCLYFETGQGSALSAGANFGADQVTMEARNYGLARYYDPFLVNTVVGFIGPEY
                     LYNDRQIIRAGLEDHFMGKLSGISMGCDCCYTNHADADQNLNENLMILLATAGCNYIM
                     GMPLGDDIMLNYQTTAFHDTATVRQLLNLRPSPEFERWLETMGIMANGRLTKRAGDPS
                     LFF"
     gene            11978..12874
                     /gene="eutC"
                     /locus_tag="OPV72_000758"
     CDS             11978..12874
                     /gene="eutC"
                     /locus_tag="OPV72_000758"
                     /EC_number="4.3.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutC"
                     /protein_id="HCR9913131.1"
                     /translation="MDQKQIEEIVRSVMASMGQDVPQPVAPSTQEGAKPQCAAPTVTE
                     SCALDLGSAEAKAWIGVENPHRADVLTELRRSTAARVCTGRAGPRPRTQALLRFLADH
                     SRSKDTVLKEVPEEWGKAQGLLEVRSEISDKNLYLTRPDMGRRLSPEAIDALKSQCVM
                     NPDVQVVVSDGLSTDAITANYEEILPPLLAGLKQAGLNVGTPFFVRYGRVKIEDQIGE
                     ILGAKVVILLVGERPGLGQSESLSCYAVYSPRVATTVEADRTCISNIHQGGTPPVEAA
                     AVIVDLAKRMLEQKASGINMTR"
     gene            12884..13543
                     /gene="eutL"
                     /locus_tag="OPV72_000759"
     CDS             12884..13543
                     /gene="eutL"
                     /locus_tag="OPV72_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutL"
                     /protein_id="HCR9913132.1"
                     /translation="MPALDLIRPSVTAMRVIASVNDGFARELKLPPHIRSLGLITADS
                     DDVTYIAADEATKQAMVEVVYGRSLYAGAAHGPSPTAGEVLIMLGGPNPAEVRAGLDA
                     MVASIENGAAFQWANDAENTAFLAHVVSRTGSYLSSTAGIALGDPMAYLVAPPLEATF
                     GIDAAMKSADVQLVTYVPPPSETNYSAAFLTGSQAACKAACNAFTDAVLDIARNPVQR
                     A"
     gene            13556..14050
                     /gene="eutK"
                     /locus_tag="OPV72_000760"
     CDS             13556..14050
                     /gene="eutK"
                     /locus_tag="OPV72_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutK"
                     /protein_id="HCR9913133.1"
                     /translation="MINALGLLEVDGMVAAVDAADAMLKAANVRLLSHQVLDPGRLTL
                     VVEGDLAACRAALDAGSAAAQHTGRVISRKEIGRPEEDTQWLIGGFARATTPTEKAPQ
                     VPATPEFAEALLALLASVRQGMTAGEVAAHFGWPLEQARNVLEQLFSDGALRKRSSRY
                     RIKN"
     gene            14098..15150
                     /gene="eutR"
                     /locus_tag="OPV72_000761"
     CDS             14098..15150
                     /gene="eutR"
                     /locus_tag="OPV72_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator EutR"
                     /protein_id="HCR9913134.1"
                     /translation="MKKTRTANLHHLYHEALPEDVKLTPRVEVDNVHQRRTTDVYEHA
                     LTITAWQQIYDQLHLGKFHGEFTEILLDEIQVFREYTGLALRQSCLVWPNSFWFGIPA
                     TRGEQGFIGAQGLGSAEIATRPGGTEFELSTPDDYTILGVVISEDVISRQATFLHNPE
                     RVLHMLRNQLALEVKEQHKAALWGFVQQALATFSESPETLHQPAVRKVLSDNLLLAMG
                     TMLEEAKPIHSAESISHQGYRRLLSRAREYVLENMSEPLTVLDLCNQLHVSRRTLQNA
                     FHAILGIGPNAWLKRIRLNAVRRELISPWSQSTTVRDAAMQWGFWHLGQFATDYQQLF
                     AEKPSLTLHQRMRQWA"
     gene            complement(15350..16627)
                     /locus_tag="OPV72_000762"
     CDS             complement(15350..16627)
                     /locus_tag="OPV72_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1963 domain-containing protein"
                     /protein_id="HCR9913135.1"
                     /translation="MDERIPCKNPQCSHFILPATAARTEGYCMPCVQARYRQEQEEYI
                     RKNRKTIDAFSGITNPVEMLKLVHEPREHDPLIEWIPCPIPTDELYKKLSDDESRDMV
                     DYAEELFDSGWQEEAQEIALCLAAFTQANLDNFLRQVINEEELELSSPLPFHRAPPDV
                     RDALLQKVETDDENRDGILCALAWIGDEVVVEHFNRWRQEPPAWSASLHILPHRYAHQ
                     AGWELTENGRRRDLYFTQCTHLVKQAPEQPAVFRAVAEYGENCPHCSLPLINLFEVAP
                     SAVGLSTQGWPGQIRILTCQCCTAYNTVFATVDPQGQPRWYEKNALSTLAVENSSDWI
                     TLPLDVLHPGESRLPLFAAEIFLPTTFSQLGGHPAWVQDTDYPTCPTCAQTMMFLAQL
                     SYEDIEEEEYAEGMLYGFICPSCQTTATSYQQT"
     gene            complement(16756..17085)
                     /locus_tag="OPV72_000763"
     CDS             complement(16756..17085)
                     /locus_tag="OPV72_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913136.1"
                     /translation="MQTNTRKVVTSDAKWHPHLGISFIGCLLAITLEIYFEERIFIPH
                     SGGVSFGLIVLLVINMVTIPVVMALIALLCFIIHIPRKSVNCILLCLLACILTIAGLF
                     IAYPVGR"
     gene            complement(17106..18005)
                     /gene="hemF"
                     /locus_tag="OPV72_000764"
     CDS             complement(17106..18005)
                     /gene="hemF"
                     /locus_tag="OPV72_000764"
                     /EC_number="1.3.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-dependent coproporphyrinogen oxidase"
                     /protein_id="HCR9913137.1"
                     /translation="MKPDAHHVKQFLLRLQDDICQTLSAVDGANFIEDSWRREAGGGG
                     RSRVLRNGGIFEQAGVNFSHVHGDAMPASATAHRPELAGRSFEAMGVSLVVHPHNPYI
                     PTSHANVRFFIAEKPGADPVWWFGGGFDLTPYYGFEEDAVHWHRTARDLCQPFGDDVY
                     PRYKKWCDDYFFLKHRNEQRGIGGLFFDDLNTPDFDHCFAFMQAVGNGYTEAYLPIVE
                     RRKAMVWGERERNFQLYRRGRYVEFNLVWDRGTLFGLQTGGRTESILMSMPPLVRWEY
                     DWQPEAGSPEAALSEFIQVRDWI"
     gene            complement(18008..18877)
                     /gene="amiA"
                     /locus_tag="OPV72_000765"
     CDS             complement(18008..18877)
                     /gene="amiA"
                     /locus_tag="OPV72_000765"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase AmiA"
                     /protein_id="HCR9913138.1"
                     /translation="MSTFKLLKTLTSRRQVLKTGLAALTLSGMSHAIAKEETLKTSNG
                     HSKPKTKKTGSKRLVMLDPGHGGIDTGAIGRNGSQEKHVVLAIAKNVRAILRNHGIDA
                     RLTRTGDTFIPLYDRVEIAHKHGADLFMSIHADGFTNPKAAGASVFALSNRGASSAMA
                     KYLSERENRADEVAGKKATDRDHLLQQVLFDLVQTDTIKNSLTLGSHILKKIKPIHKL
                     HSRTTEQAAFVVLKSPSIPSVLVETSFITNPEEERLLGTTAFRQKIATAIANGIISYF
                     HWFDNQKAHTKKR"
     gene            19090..19515
                     /locus_tag="OPV72_000766"
     CDS             19090..19515
                     /locus_tag="OPV72_000766"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311332.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HCR9913139.1"
                     /translation="MEIRVFRQEDFEEVITLWERCDLLRPWNDPEMDIERKVNHDVSL
                     FLVAEVSGEVVGTVMGGYDGHRGSAYYLGVHPEFRGRGIANALLNRLEKKLIARGCPK
                     IQIMVRDDNDVVLGMYERLGYEHSDALSLGKRLIEDEEY"
     gene            19502..19951
                     /locus_tag="OPV72_000767"
     CDS             19502..19951
                     /locus_tag="OPV72_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2919 domain-containing protein"
                     /protein_id="HCR9913140.1"
                     /translation="MKSTEFHPADYDVHGCLRLPFLFWCVLLLQARAWVLFVIAGSSR
                     GQGNTLLNFFYPDHDNFWLGLLPGVPAVVAFLLSGRREAVPGVWRWLRGLLILAQLVS
                     LCWLPVMWLGGDPVNGVGLALLLADIVALIWLLTNQRLRACFSLEKE"
     gene            20013..20588
                     /locus_tag="OPV72_000768"
     CDS             20013..20588
                     /locus_tag="OPV72_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpoE-regulated lipoprotein"
                     /protein_id="HCR9913141.1"
                     /translation="MKSLRLTLLALPLALTGCSTLSSVNWSAANPWNWFGSSTEVTEQ
                     GVGALTAATPLEEPAIAEALDGDYRLRSGMKTDNGNVVRFFEAMKGDSVAMVINGEQG
                     TVSRIDVLDSDIPTAAGGKIGTPFSDLYSKAFGHCEPVSSDSHTSVECKAEGSQHISY
                     VFSGEWSGPEGLMPPDDVLKNWDVRKIIWRR"
     gene            20683..21582
                     /gene="yfeX"
                     /locus_tag="OPV72_000769"
     CDS             20683..21582
                     /gene="yfeX"
                     /locus_tag="OPV72_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphyrinogen peroxidase"
                     /protein_id="HCR9913142.1"
                     /translation="MSQVQSGILPEHCRAAIWIEANVKGDLDALRAASRTFADKLATF
                     EVKFPDAHLGAVVAFGNNTWRALSGGVGAEELKDFIPYGKGLAPATQYDVLIHILSLR
                     HDVNFSVAQAAMEAFGDCIDVKEEVHGFRWVEERDLSGFVDGTENPAGEETRREVAVI
                     KDGVDAGGSYVFVQRWEHNLKQLNRMSIHDQEMMIGRTKEANEEIDGDARPATSHLSR
                     VDLKEDGKGLKIVRQSLPYGTASGTHGLYFCAYCARLHNIEQQLLSMFGDTDGKRDAM
                     LRFTKPVTGGYYFAPSLDRLLAL"
     gene            21819..22610
                     /gene="ucpA"
                     /locus_tag="OPV72_000770"
     CDS             21819..22610
                     /gene="ucpA"
                     /locus_tag="OPV72_000770"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase UcpA"
                     /protein_id="HCR9913143.1"
                     /translation="MGKLTGKTALITGASQGIGEGIARVFARHGANLILLDISDEIEK
                     LADELGGRGHRCTAVKADVRDFASVQAAVARAKETEGRIDILVNNAGVCRLGNFLDMS
                     EEDRDFHIDINIKGVWNVTKAVLPEMIKRKDGRIVMMSSVTGDMVADPGETAYALSKA
                     AIVGLTKSLAVEYAQSGIRVNAICPGYVRTPMAESIARQSNPDDPESVLTEMAKAIPL
                     RRLADPLEVGELAAFLASDESSYLTGTQNVIDGGSTLPESVSVGV"
     gene            22768..23784
                     /gene="cysP"
                     /locus_tag="OPV72_000771"
     CDS             22768..23784
                     /gene="cysP"
                     /locus_tag="OPV72_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate/sulfate ABC transporter
                     substrate-binding protein CysP"
                     /protein_id="HCR9913144.1"
                     /translation="MAVNLLKKRLLTLAAMLLLAGQAQATELLNSSYDVSRELFAALN
                     PPFEQQWAKDNGGDKLTIKQSHAGSSKQALAILQGLKADVVTYNQVTDVQILHDKGKL
                     IPADWQSRLPNNSSPFYSTMGFLVRKGNPKNIHDWSDLVRSDVKLIFPNPKTSGNARY
                     TYLAAWGAADNADGGDKAKTEQFMTQFLKNVEVFDTGGRGATTTFAERGLGDVLISFE
                     SEVNNIRKQYEAQGFEVVIPKTNILAEFPVAWVDKYVKANGTEKAAKAYLNWLYSPQA
                     QTIITHYYYRVNNPEIMGKQADKFPQTGLFRVEDKFGTWPEVMKTHFASGGELDKLLA
                     AGRK"
     gene            23784..24617
                     /gene="cysT"
                     /locus_tag="OPV72_000772"
     CDS             23784..24617
                     /gene="cysT"
                     /locus_tag="OPV72_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/thiosulfate ABC transporter permease
                     CysT"
                     /protein_id="HCR9913145.1"
                     /translation="MLAVSSRRVLPGFTLSLGTSLLFVCLILLLPLSALVMQLSQMSW
                     SQYWDVVTNPQVVAAYKVTLLAAFVASIFNGVFGLLMAWILTRYRFPGRTLLDALMDL
                     PFALPTAVAGLTLASLFSVNGFYGQFLAQFDIKVTYTWLGIAVAMAFTSIPFVVRTVQ
                     PVLEELGPEYEEAAQTLGATRLQSFRKVVLPELSPALIAGVALSFTRSLGEFGAVIFI
                     AGNIAWKTEVTSLMIFVRLQEFDYPAASAIASVILAASLLLLFSINTLQSRFGRRVVG
                     H"
     gene            24617..25492
                     /gene="cysW"
                     /locus_tag="OPV72_000773"
     CDS             24617..25492
                     /gene="cysW"
                     /locus_tag="OPV72_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/thiosulfate ABC transporter permease
                     CysW"
                     /protein_id="HCR9913146.1"
                     /translation="MAEVTQLKRYDVPRINWGKWFLIGVGMLVSAFILLVPMIYIFVQ
                     AFSKGLMPVLQNLADPDMLHAIWLTVLIALIAVPMNLVFGILLAWLVTRFNFPGRQLL
                     LTLLDIPFAVSPVVAGLVYLLFYGSNGPLGGWLDEHNLQMMFSWPGMVLVTIFVTCPF
                     VVRELVPVMLSQGSQEDEAAILLGASGWQMFRRVTLPNIRWALLYGVVLTNARAIGEF
                     GAVSVVSGSIRGETLSLPLQIELLEQDYNTVGSFTAAALLTLMAIITLFLKSMLQWRL
                     ENQEKRAQQEENHEH"
     gene            25482..26576
                     /gene="cysA"
                     /locus_tag="OPV72_000774"
     CDS             25482..26576
                     /gene="cysA"
                     /locus_tag="OPV72_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/thiosulfate ABC transporter ATP-binding
                     protein CysA"
                     /protein_id="HCR9913147.1"
                     /translation="MSIEIARIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTL
                     LRIIAGLEHQSSGHIRFHGTDVSRLHARERKVGFVFQHYALFRHMTVFDNIAFGLTVL
                     PRRDRPTAAAIKTKVTQLLEMVQLAHLADRFPAQLSGGQKQRVALARALAVEPQILLL
                     DEPFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEATEVADRVVVMSQGNIEQA
                     DAPDRVWREPATRFVLEFMGEVNRLTGTVRGGQFHVGAHRWPLGYTPAYQGPVDLFLR
                     PWEVDISRRTSLDSPLPVQVIEASPKGHYTQLVVQPLGWYHDPLTVVMAGDDVPQRGE
                     RLFVGLQNARLYHGDQRIEPHEALALAESA"
     gene            26697..27608
                     /gene="cysM"
                     /locus_tag="OPV72_000775"
     CDS             26697..27608
                     /gene="cysM"
                     /locus_tag="OPV72_000775"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase CysM"
                     /protein_id="HCR9913148.1"
                     /translation="MNTLEQTIGNTPLVKLQRLGPDNGSEIWVKLEGNNPAGSVKDRA
                     ALSMIVEAEKRGEIKPGDALIEATSGNTGIALAMIAALKGYRMKLLMPDNMSQERRAA
                     MRAYGAELILVTKEQGMEGARDLALAMSERGEGKLLDQFNNPDNPYAHYTTTGPEIWR
                     QTSGRITHFVSSMGTTGTITGVSRFLREQEKTVTIVGLQPEEGSSIPGIRRWPTEYMP
                     GIFNASLVDEVLDIHQNDAENTMRELAVREGIFCGVSSGGAVAGALRVARATPGAIVV
                     AIICDRGDRYLSTGVFGEEHFSQGAGI"
     gene            complement(27641..28018)
                     /locus_tag="OPV72_000776"
     CDS             complement(27641..28018)
                     /locus_tag="OPV72_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfeK family protein"
                     /protein_id="HCR9913149.1"
                     /translation="MKKDFTMKKIVCAVVALLLTLPAWAKLNAHEEARINAMLNVLAQ
                     KKDLTFVRNGDAHNCEEAVSHLRLKLGNTRNRIDTAEQFIDKVASSSSITGKPYIVKI
                     PGKSDENAQPYLHALIAETDKTL"
     gene            complement(28077..28796)
                     /locus_tag="OPV72_000777"
     CDS             complement(28077..28796)
                     /locus_tag="OPV72_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP synthase"
                     /protein_id="HCR9913150.1"
                     /translation="MRVHFVIHESFESAGAYLKWAEDRGYTISWSRVYAGEALPPNAD
                     EFDMLVVFGGPQSPRTTREECPYFDSQAEQHLINQAISARKIVVGICLGSQLIGEALG
                     AKVCQSPEKEIGHYPIVLTEAGQQHPLFNHFGSPLIVGHWHNDMPGLTDQAIILATSE
                     GCPRQIVQYGNFVYGFQCHMEFTVEAVEGLIQHSQQELADAQGKRFIRSVAEMRAWNY
                     QQMNEKLWRFLDELTLAHSQK"
     gene            complement(28811..30103)
                     /gene="ptsJ"
                     /locus_tag="OPV72_000778"
     CDS             complement(28811..30103)
                     /gene="ptsJ"
                     /locus_tag="OPV72_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator PtsJ"
                     /protein_id="HCR9913151.1"
                     /translation="MIDGKTANEIFDSIRQHIIAGTLRAKDSLPPVRELASELKVNRN
                     TVAAAYKRLITAGLAQSLGRNGTVIKGSPSPVALEGGDPHTPLHDLSGGNPDPQRLPD
                     LSRYFARLSRTPHLYGDAPVSPELHAWAARWLRDATPVAGEIDITSGAIDAIERLLCA
                     HLLPGDSVAVEDPCFLSSINMLRYAGFSASPVSVDSEGMQPEKLEQALNQGARAVILT
                     PRAHNPTGCSLSARRAAALQNILARYPQVLVIIDDHFALLSSSPWQPVIAQTTQHWAV
                     IRSVSKALGPDLRLAIVASDSSTSAKLRLRLNAGSQWVSHLLQDLVYACLTDPEYQHR
                     LAQTRLFYATRQQKLARALQQYGIAISPGDGVNAWLPLDTHSQATAFTLAKSGWLVRE
                     GEAFGVSAPSHGLRITLSTLNDGEINTLAADIHQALNR"
     gene            30186..31052
                     /gene="pdxK"
                     /locus_tag="OPV72_000779"
                     /gene_synonym="thiJ"
     CDS             30186..31052
                     /gene="pdxK"
                     /locus_tag="OPV72_000779"
                     /gene_synonym="thiJ"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxine/pyridoxal/pyridoxamine kinase"
                     /protein_id="HCR9913152.1"
                     /translation="MGQESDIQSVLFDDNHRALQTDIVAVQSQVVYGSVGNSIAVPAI
                     KAQGLRVTAVPTVLFSNTPHYKTFYGGIIPAEWFAGYLTALNERDALRELKAITTGYM
                     GSADQIVLLSKWLMAIRASHPEVCILVDPVIGDTDSGMYVQAEIPQAYRTHLLPQAQG
                     LTPNVFELEMLSGKPCRTLEEAVAAAQSLLSDTLKWVVITSAPGESLETITVAVVTAQ
                     VVEVFAHPRVATELKGTGDLFCAELVSGIVQGKKLTTAAKDAAQRVLEVMTWTQQCGC
                     DELILPPAGEAR"
     gene            31049..31288
                     /locus_tag="OPV72_000780"
     CDS             31049..31288
                     /locus_tag="OPV72_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HCR9913153.1"
                     /translation="MKSYRLVVRQQGRIVGHFETSGLDALEDICVARAMFGITGGYQC
                     ELQVSDSERRILESGPDGMKILMREKCFRPVTSQL"
     gene            complement(31438..31947)
                     /gene="crr"
                     /locus_tag="OPV72_000781"
     CDS             complement(31438..31947)
                     /gene="crr"
                     /locus_tag="OPV72_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015833547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCR9913154.1"
                     /translation="MGLFDKLKSLVSDDKKDTGTIEIVAPLSGEIVNIEDVPDVVFAE
                     KIVGDGIAIKPTGNKMVAPVDGTIGKIFETNHAFSIESDSGIELFVHFGIDTVELKGE
                     GFKRIAEEGQRVKVGDPVIEFDLPLLEEKAKSTLTPVVISNMDEIKELIKLSGSVTVG
                     ETPVIRIKK"
     gene            complement(31988..33715)
                     /gene="ptsI"
                     /locus_tag="OPV72_000782"
     CDS             complement(31988..33715)
                     /gene="ptsI"
                     /locus_tag="OPV72_000782"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate-protein phosphotransferase
                     PtsI"
                     /protein_id="HCR9913155.1"
                     /translation="MISGILASPGIAFGKALLLKEDEIVIDRKKISADKVDQEVERFL
                     SGRAKASAQLEAIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADA
                     AAHEVIEGQATALEELDDEYLKERAADVRDIGKRLLRNILGLAIIDLSAIQEEVILVA
                     ADLTPSETAQLNLQKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTAQVKNGDYL
                     ILDAVNNQVYVNPTNDVIEQLRAVQEQVATEKAELAKLKDLPAITLDGHQVEVCANIG
                     TVRDVEGAERNGAEGVGLYRTEFLFMDRDALPTEEEQFAAYKAVAEACGSQAVIVRTM
                     DIGGDKELPYMNFPKEENPFLGWRAVRIAMDRKEILRDQVRAILRASAFGKLRIMFPM
                     IISVEEVRALRKEIEIYKQELRDEGKAFDESIEIGVMVETPAAATIARHLAKEVDFFS
                     IGTNDLTQYTLAVDRGNDMISHLYQPMSPSVLNLIKQVIDASHAEGKWTGMCGELAGD
                     ERATLLLLGMGLDEFSMSAISIPRIKKIIRNTNFEDAKVLAEQALAQPTTDELMTLVN
                     KFIEEKTIC"
     gene            complement(33764..34021)
                     /gene="ptsH"
                     /locus_tag="OPV72_000783"
     CDS             complement(33764..34021)
                     /gene="ptsH"
                     /locus_tag="OPV72_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein Hpr"
                     /protein_id="HCR9913156.1"
                     /translation="MFQQEVTITAPNGLHTRPAAQFVKEAKGFTSEITVTSNGKSASA
                     KSLFKLQTLGLTQGTVVTISAEGEDEQKAVEHLVKLMAELE"
     gene            complement(34405..35376)
                     /gene="cysK"
                     /locus_tag="OPV72_000784"
     CDS             complement(34405..35376)
                     /gene="cysK"
                     /locus_tag="OPV72_000784"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HCR9913157.1"
                     /translation="MSKIYEDNSLTIGHTPLVRLNRIGNGRILAKVESRNPSFSVKCR
                     IGANMIWDAEKRGVLKPGVELVEPTSGNTGIALAYVAAARGYKLTLTMPETMSIERRK
                     LLKALGANLVLTEGAKGMKGAIQKAEEIVASDPQKYLLLQQFSNPANPEIHEKTTGPE
                     IWEDTDGQVDVFISGVGTGGTLTGVTRYIKGTKGKTDLITVAVEPTDSPVIAQALAGE
                     EIKPGPHKIQGIGAGFIPGNLDLKLIDKVVGITNEEAISTARRLMEEEGILAGISSGA
                     AVAAALKLQEDESFTNKNIVVILPSSGERYLSTALFADLFTEKELQQ"
BASE COUNT         7740 a         9412 c        10463 g         8055 t
ORIGIN      
        1 gcgccgctgg gcttcgccat ggtatgaaag gctcgggtgg ggatattctg gaacctattg
       61 cgttacccct acttatttca ctgaatctgt actatgcaca aatcgagtga tacgcattat
      121 ttttatcaat aatagtaata caaagaatag ccggtgggta tttattgcgg aacaagctta
      181 aattcagaat gacgcctgaa aatgtgatgc accacgatat ttatcgttaa caccttcgac
      241 agaagtccct tttattttct ttctcttagt gatctacctc accttttaca tcaccttgcc
      301 gaattttgtt atttactccg acaaaaaatt gccacgatga cggcagtttc agtggagacg
      361 gtgagcaatg aataaagaac gcattattca ggaatttgtg ccgggcaaac aggtcacgct
      421 ggcgcatctc attgcgcacc ctggtgaaga actggcgaaa aagatcggcg ttcccgatgc
      481 tggcgcgatt ggcattatga ccttaacgcc gggggaaacg gccatgatcg ctggcgattt
      541 agcgatgaag gctgcggatg tacacatcgg ttttctcgac agatttagcg gcgcgctggt
      601 gatttatggc accgtcggcg cagtagaaga agcgctatta cagacggtca gcgggctggg
      661 gcgattatta aacttcaccc tgtgtgagtt aacaaaaagt taattggtgg cggtaatgaa
      721 acgtattgct tttgtcggcg cggtcggcgc cggaaagaca acgcttttta acgcgttacg
      781 gggaaattat tccctcgcca gaaaaacgca ggccgtggaa tttaatgatc atggcgatat
      841 cgatacgccg ggtgaatatt ttagccatcc ccgttggtat cacgccttaa ttaccacgtt
      901 gcaggatgtg gacacgctga tttatgtcca cgcggcaaac gataaagaaa gtcgcttacc
      961 tgccgggtta ttggatgttg gaacccgtaa acgacatatc gccgttatca gcaaaacgga
     1021 catgccggat gccgacgtcg ccgctacgcg gcagttgctt tgcgagattg gattccggga
     1081 gccgattttc gagctcaacg gccacgaccc gcaaagcgtg cggcagttgg tggattatct
     1141 ggcggctctc agtgaacagg aggaagaggc aggtgaaaaa acttatcaca gctaacgata
     1201 ttcgtgcggc ccacgcccgc ggcgaacagg cgatgtcggt agtgctgcgc gccagcatta
     1261 ttaccccgga ggctcgcgaa gtggcggaac tactgggctt cacgattacc gaatgcgacg
     1321 agtccgtccc ggcatccaca tcggcgcagg cgtgtaaaag cgaaagccag cgcattcggg
     1381 aagccatcat cgcgcagcgc ccggaagggc agtttactga aagcctggtg gcgcagttga
     1441 tggaaaaagt gctcaaggaa aagcagtcgc tggaactggg gacgatgcag ccgagcttta
     1501 cctccgtcac gggtaaaggc ggcgtgaaag tcattgacgg cagcagcgtg aaatttggcc
     1561 gcttcgacgg cgccgaaccg cactgcgtcg gcttaaccga tctggttaca gagcaggatg
     1621 gcagcagcat ggccgccggg tttatgcagt gggacaacgc ctttttcccg tggacgctga
     1681 actacgacga aatcgacatg gtgctggagg gtgaactgca cgtacgccat gaaggcgaaa
     1741 ccatgattgc caaagccgga gatgtcatgt tcatccctaa aggctccagc attgaatttg
     1801 gcacgccaac gtccgtgcgc tttctgtacg tcgcctggcc tgcaaactgg caatccgtat
     1861 gaacgatttc atcaccgaaa cgtggctcag agcgaatcat acgctcagcg aaggatcgga
     1921 aatccatctg cccgctgacg cacgactgac gccctcggcc cgggaactgc tggaaagtcg
     1981 tcgcctgcgc attaagtttc tggatcagca aggccggctg tttgtcgatg atgacgaaca
     2041 gcagccggta catggcttaa ccagtagcga tacgcaccca caggcctgct gtgaactgtg
     2101 ccgccagccg gtggtgaaaa agcccgatac gctgacccat ctgacggcgg acaaaatggt
     2161 cgccaaaagc gacccgcgcc tcggctttcg cgccgcgctc gacagcgcca tcgcgctgac
     2221 cgtgtggcta caaatcgaac tggcggaacc ctggcagccg tggcttttcg atatccgctc
     2281 gcggctgggc aacattatgc gcgccgacgc tatagatgaa ccgctggcgg cgcagtctat
     2341 cgtcgggctg aacgaggatg agctgcatcg gctttcccac cagccgctgc gctatctcga
     2401 ccacgatcac ctggtgccgg aggccagcca cggtcgcgat gcggcgctgc ttaatctgct
     2461 gcgaaccaaa gtccgcgaaa cggaaaccct cgccgcacaa gtgtttatta cccgtagttt
     2521 tgaggtcttg cgcccggaca ttttacaggc gctaaaccgt ctctccagca cggtttacgt
     2581 gatgatgatt ttgagcgtgg cgaaacatcc gctgacggtc gcccaaattc aacaacggtt
     2641 gggagagaag ccatgatcat tgaacgcgcc cgcgaactgg cggtacgcgc ccccgccaga
     2701 gtcgtctttc ccgatgcgct ggacgaacgc gtgctgaaag cggcgcatta cctgcaacag
     2761 tgcggtctgg ctcgccccgt tctggtcgcc agtccgtttg cgctgcgtca gtttgccctg
     2821 agtcatcgta tggcgatgga tggcattcag gtcatcgacc cacacagcaa cctgagtatg
     2881 cgccagcgtt ttgcgcaacg ctggcttgcc cgtgccggag aaaaaacgcc gccggacgca
     2941 gtggaaaagc ttagcgaccc gctaatgttc gctgccgcca tggtgagcgc cggtgaggct
     3001 gatgtgtgta tcgcaggcaa cctgtcgtca acggcgaacg tgctgcgcgc agggctgcgg
     3061 gtgattggcc tgcaacccgg gtgcaaaaca ttatcgtcta ttttcctgat gctgccgcag
     3121 tatgccggcc cggcattagg gttcgccgat tgcagcgtag tgccgcagcc gacggcggcg
     3181 cagctggcgg atatcgctat cgccagcgcc gacacctggc gggccattac cggcgaagag
     3241 ccgcgcgtgg cgatgctgtc attttcaagc aacggcagcg cccgtcaccc caatgttgcc
     3301 aacgtgcagc aggcgacaga gttcgttcgc gaacgtgcgc cgcaactgct tgtggacggt
     3361 gaattgcagt ttgacgccgc tttcgtaccg gaggtcgccg cgcaaaaagc gcctgacagc
     3421 ccgctgcaag gccgcgccaa cgtgatgatt ttcccgtcgc tggaggcggg caatattggc
     3481 tacaaaatcg ctcagcgtct gggaggctat cgcgctgttg ggccgctaat tcaggggctt
     3541 gccgcgccgc ttcacgacct ctcccgaggc tgtagcgtgc aggaaattat cgaactggcg
     3601 ttggtggcag ccgtgccgcg ccaggctgac gtgagccgcg aacgcagctt acacacactg
     3661 gttgaatgaa cggtcccgtt ctggacccct ttaatgagag gaaaacacga tggaagcatt
     3721 aggaatgatt gaaacccggg gcctagttgc gctgattgag gcctcagatg cgatggtaaa
     3781 agccgcacgc gtgaagctgg tcggtgtgaa gcagattggc ggtggcctgt gtacggccat
     3841 ggtgcgtggc gacgtggcgg cgtgcaaagc cgcaaccgat gctggcgccg ctgcggcgca
     3901 gcgcattggc gagctggtct ctgtacacgt gattccacgc ccgcacggcg atctggaaga
     3961 agtgttcccg atcagcttca aaggcgcagc aacatttgat ggtaggccgg ataagacgcg
     4021 cagcgtcgcc atccggcatg aatgcgcgcc attgcctgat agtgcgcaga ttcaaggcct
     4081 acgacccaac gggcaatcca tggaggcgga tatgaaactg gcagtcgtca caggacaaat
     4141 cgtatgtacc gtccgccatc agggactggc gcatgacaaa ttgctgatgg tggaaatgat
     4201 cgatgcccag ggcaaccccg acgggcagtg tgccgtcgct atcgacagta tcggggcggg
     4261 aaccggagag tgggtactgc tggtcagcgg cagttccgcg cgccaggcgc atcgcagcga
     4321 attatcaccg gtcgatctgt gcgtcattgg catcgtcgat gaagtggtgg ctggcgggaa
     4381 agtggttttc cataaatagg actgaacatc atgaatcaac aggatattga acaggtggtg
     4441 aaagcggtgc tgctgaaaat gaaagacagc agccagccgg ccagcactgt tcatgagatg
     4501 ggcgtttttg cctccctgga tgacgaagtg gcggcagcaa aacgggccca gcaggggctg
     4561 aagagcgtgg cgatgcgcca gcttgccatt catgccattc gcgaggcggg cgaaaaacac
     4621 gcccgagaat tagcggaact tgccgtcagc gaaaccggca tgggacgcgt tgacgataaa
     4681 tttgccaaaa acgtggcgca ggcgcgcggc acgccgggcg tcgagtgttt atctccgcag
     4741 gtgctgaccg gcgataacgg cctgacattg attgaaaatg cgccgtgggg cgtggtggcc
     4801 tcggtcacgc cgtccaccaa tccggcggcg acggtgatca ataacgccat cagcctgatt
     4861 gccgcaggca acagcgtcgt gtttgccccg catccggcgg cgaaaaaggt ctctcagcgg
     4921 gcaatcaccc tcctcaatca ggcggtggtc gccgccggcg gcccggaaaa tctgctggtc
     4981 accgtggcga acccggatat cgaaaccgcc cagcggctgt tcaagtaccc cggtattggc
     5041 ctgctggtgg tgaccggcgg cgaagcggtg gtggacgcgg cgcgcaaaca tactaataaa
     5101 cgcctgatcg ccgccggtgc cggcaatccc ccggtggtgg tggatgagac cgccgacctg
     5161 ccgcgcgccg cacaatccat cgtcaaaggc gcgtcgtttg ataacaacat catctgtgcc
     5221 gacgaaaaag tgctgattgt ggtggatagc gtcgccgacg agctgatgcg tctgatggaa
     5281 ggtcagcacg cggtgaaact gactgccgct caggccgaac agctccagcc ggtgctgctg
     5341 aagaatattg atgagcgcgg caaaggcacc gtcagccgtg actgggtcgg tcgtgacgcg
     5401 ggcaaaatcg ccgcagccat tggcctgaac gtcccggatc aaacgcgcct gctatttgtg
     5461 gaaacgccag ctaaccatcc gtttgccgtc actgaaatga tgatgccggt actgccggtg
     5521 gtgcgggtcg ccaacgtcga agatgccatc gccctggcgg tacaacttga aggcggttgc
     5581 caccatacgg cggcgatgca ctcgcgcaat atcgacaaca tgaaccagat ggcgaacgcc
     5641 atcgacacca gcattttcgt caaaaacggg ccgtgcattg ccgggcttgg attgggcgga
     5701 gaaggctgga ccaccatgac tatcactacg ccaaccggcg aaggggtgac cagcgcgcgt
     5761 acctttgtgc ggctgcgtcg atgcgtgctg gtggatgcgt ttcgcattgt ataagggatg
     5821 actcatggcg cacgacgaac aactctggct caccccaaga ctgcaaaaag cggcggccct
     5881 gtgtaaccag acgcccgccg ccagcgacac accgctgtgg ctgggcgtcg atttgggcac
     5941 ctgcgacgtg gtgtcgatgg tggtcgacgg caacgcccag ccggtggcgg tgtgccttga
     6001 ctgggccgac gttgtgcgtg acggcatcgt ctgggatttc ttcggcgccg tcaccctcgt
     6061 gcgccgccat ctcgacaccc ttgaacagca gctcggctgc cgctttaccc acgcggcgac
     6121 ctcgttccca ccgggcaccg acccgcgtat ttcgatcaac gtgctggagt ctgctgggtt
     6181 agaagtcagc cacgtactgg atgaaccgac ggcggtggcg gatctgctgg cgcttgataa
     6241 tgcaggcgtg gtggatattg gcggcggcac taccggcatt gccatcgtca aacagggcaa
     6301 ggtgacttac tccgccgatg aagccactgg cgggcaccat atctccctga cgctggcggg
     6361 caaccgccgt attcccctag aagaggcgga acagtacaag cgcagcaatg cgcaggagat
     6421 ttggccggta gtgaagccgg tgtacgaaaa gatggcggag atcgttgctc gccacattga
     6481 agggcaagga attgctgatt tatggctggc gggcggttcc tgtatgcagc cgggcgtgga
     6541 ggcgttattt cgccagcgtt tcccggagtt acaggtgcat ttaccgcagc acagcctgtt
     6601 tatgaccccg ctggcgatag ctaacagcgg gagagcgaaa gcgaagggac tctatgcaag
     6661 ctgaactaca gacggcgctg tttcaggcat tcaacaccct gaatctgcaa cgggtgaaaa
     6721 cgttcagcgt accgccggtc acgctgtgcg ggcttggggc gctcggcgcc tgcgggcagg
     6781 aagcgcaagc gcggggcgta agccatttgt ttgtgatggt cgacagcttc ctgcatcagg
     6841 cgggaatgac cgcgccgctg gcacgcagcc tggcgatgaa aggcgtggcg atgacggtct
     6901 ggccgtgtcc gccaggcgag ccgtgcatca ccgatgtctg cgcggcggtg gcgcaactgc
     6961 gtgaggcggc gtgcgacggc gtagtggcct ttggcggcgg ttcggtgttg gacgcggcga
     7021 aagcggtcgc cctgctggtg actaaccctg accagacgct gagcgccatg accgagcgca
     7081 gtacattacg cccgcgtctg ccgctgattg cggtgccgac caccgccgga accggttcag
     7141 aaaccaccaa cgtgacggtg attatcgacg cggtcagcgg gcgcaagcag gtgctggcac
     7201 acgcgtcact aatgccggat gtggcgattc ttgatgctgc cgtgaccgaa ggcgttccgc
     7261 caaatgtgac ggcgatgacc ggtatcgatg cgctgacgca tgcgattgag gcctacagcg
     7321 cgctcaacgc cacgccgttt accgacagcc tggcgattgg cgcgatagcg atgattggca
     7381 aatcgctgcc gaaggccgtc ggctatgggc aggatctggc ggcgcgtgaa aatatgttgc
     7441 tggcctcctg tatggcggga atggcctttt ccagcgccgg tctggggctg tgtcatgcga
     7501 tggcgcacca gccaggggcg gcgctgcata ttccgcacgg ccaggccaac gccatgctgc
     7561 tgccgacagt catgggcttt aaccggatgg tatgccgcga gcgcttcagt caaatcggtc
     7621 gggcgttaac caataagaaa tcggacgatc gcgatgcgat tgcggcggtg tgcgagctga
     7681 ttgccgaagt ggggcagagc aaacggctgg ctgacgctgg cgccaaaccc gaacactaca
     7741 gcgcgtgggc gcaagccgcg ctggaggata tttgtctgcg cagtaaccca cgcaccgcca
     7801 cacaggcaca gattatcgac ctgtacgcgg ctgccgggta atgctgtagg ccggataagg
     7861 tgctcgcatc gccatccggc aataacacgg cgttaatgcc ggaggcgacg taaacgtctt
     7921 atccggctta caaatcaaaa atgacaggga gtaggggcta tgggaattaa cgaaatcatc
     7981 atgtacatca tgatgttctt tatgctgatt gccgccgtgg acaggatcct gtcgcagttc
     8041 ggcgggtcgg cgcgcttcct cggtaaattt ggcaagagta tcgaggagtc tggcggccag
     8101 tttgaagagg gctttatggc gatgggcgcg ttgggactgg cgatggttgg tatgaccgcg
     8161 ctggcgccgg tgctggcgca tgtactgggg ccggttatta tcccggtata cgaaatgctg
     8221 ggcgcgaacc catccatgtt cgcgggtacg ctactggctt gtgatatggg cggattcttc
     8281 ctcgccaaag agctggccgg cggtgatgtc gcggcgtggc tatactcagg gttaatactt
     8341 gggtcgatga tggggccgac cattgtgttc tccattccgg tggcgctcgg cattatcgaa
     8401 ccgtctgacc gccgctacct ggcgcttggc gtactggcgg gtatcgtcac cattcccatt
     8461 ggctgcattg cgggggggtt gatcgccatg tactcaggtg tgcagatcaa tggtcagcca
     8521 gtggagttta ccttcgcgct gatcctgatg aacatgatcc cggtattgat cgtcgcggtg
     8581 ctggtagcgc tggggctgaa gttcatcccg gaaaaaatga tcaacggttt ccagattttc
     8641 gccaaatttc tggtggcgct gatcaccatc ggtctggcgg ctgcggtggt taaattcctg
     8701 ttgggctggg agttgattcc ggggctcgac ccgatcttta tggcgccagg cgacaaaccc
     8761 ggcgaagtga tgcgcgccat tgaagtgatc ggctctatct cctgcgtgct gctcggcgcg
     8821 tatccgatgg tgctgttact gacccgctgg tttgaaaaac cgttgatgaa tgtcggtaag
     8881 ctgctgaacg taaataatat tgcggcggca ggcatggtag cgaccctggc gaacaatatc
     8941 cccatgttcg gcatgatgaa gcagatggat acccgcggca aagtgattaa ctgcgcattt
     9001 gccgtctctg cggcgttcgc gctggtcgac catttaggct tcgccgctgc caacatgaac
     9061 gccatgatct tcccgatgat tgtcggcaag ctgatcggcg gcgtgacggc gattggcgtg
     9121 gcgatgatgc tggtgccgaa agatgacgcc gcccaggtga aaaccgaagc ggaggcgcaa
     9181 tcgtgaacac tcgccagcta ctgagcgtcg gtatcgatat cggcaccacc accacgcagg
     9241 tgatcttctc gcgcctggag ttggttaacc gtgcggcggt gtcgcaggtg ccgcgctacg
     9301 aattcatcaa acgcgacatt agctggcaaa gcccggtctt ctttacgccc gtggataagc
     9361 agggcggtct gaaagaggca gaacttaaag cgctgattct ggctcagtat caggccgcag
     9421 gcatcgcgcc tgaatcggtg gactcagggg ctatcattat caccggcgaa agcgccaaaa
     9481 cccgcaacgc ccgtccggcg gtcatggcgc tctcgcagtc gctgggcgac tttgtggtcg
     9541 ccagcgccgg gccgcatctg gaatcggtca ttgccggtta cggcgccggg gcgcaaagcc
     9601 tgtctgagca gcggatgtgc cgggtgctga atattgatat cggcggcggc acgtctaact
     9661 acgcgctgtt tgacgcggga aaagtcagcg gcaccgcctg ccttaacgtc ggtggtcgcc
     9721 tgctggaaac cgacgctcag gggcgcgtgg tttatgccca tcagccgggg cagatgatta
     9781 tcgatgaggt gttcggttcg ggtactgatg ctcgcgcctt agctgccgca cagttggggc
     9841 aggtggcgcg gcggatggcg gatctcatcg tcgaggttat cactggcgcg ctctcgccgc
     9901 tggcgcaatc gctgatgcaa accgggctgc tgcccgccga tattacgccg gaggtgatca
     9961 ccctttccgg tggagtaggt gaatgctacc gcaaccaacc tgccgatccg ttctgctttt
    10021 ctgatatcgg gccgctgctg gcgaccgcgc tgcatgagca cccgcgtctg cgcgagatga
    10081 acgtgcagtt tccggcgcaa accgtacgcg ccacggtgat tggcgcgggg gcccatacgc
    10141 tctcgctttc cggcagtact atctggctgg aagacgtcca actgccgctg cgcaacctgc
    10201 cggtggcgat cccgcaggat gacgccgatt tggtgaacgc ctggcggcag gcgcttctcc
    10261 agcttgatct cgacccgcaa accgacgctt acgtgctggc gcttccctcc acgcttccgg
    10321 tgcgttacgc cgcattactc acggtcatca acgcgctgac ggcttttgtc gcgcgttatc
    10381 ccaatccaca tcccctgctg gtggtggccg agcaggattt tggtaaagcg ctgggcatgt
    10441 tattgcgccc acagttaccg caacttccgc tggcggtcat cgatgaggtg gtcgtgcggg
    10501 cgggagacta tatcgacatt ggtacgcctc tttttggcgg atcggttgtg ccggtgacgg
    10561 tgaaatcact cgcatttcct tcctgaggga acgacttatg aaactaaaga ccacattgtt
    10621 cggcaatgtt tatcagttta aggatgtaaa agaggtactg gctaaagcca acgaactgcg
    10681 ttcgggggat gtgctggccg gggttgccgc ggcaagttcg caggagcgcg tagcggcaaa
    10741 acaggtactg tcggaaatga cggtggcgga tatccgcaac aatccggtga ttgcctatga
    10801 agaggactgc gtgacgcgcc tgattcagga tgacgtcaac gaaacggcct ataatcggat
    10861 taaaaactgg agcatcagcg aactgcgcga atacgtactg agcgatgaaa cctccgtgga
    10921 cgacatcgcg tttacccgca aaggcctgac ctccgaagtg gtggcggcag tggcgaaaat
    10981 ctgctccaac gccgacctga tctacggcgg taagaaaatg ccggtgatca aaaaagccaa
    11041 taccaccatc ggtattccgg gcacctttag ctgccgtttg cagccgaacg atacccgtga
    11101 cgatgtgcag agtatcgccg cgcaaatcta cgaagggctt tctttcggcg caggcgatgc
    11161 ggtgatcggc gttaacccgg tgaccgatga cgtggagaac ctgacccgcg tgctcgacac
    11221 cgtttacggc gttatcgata aattcaatat tccgacccag ggctgcgtgc tggcgcacgt
    11281 caccacccag attgaagcga ttcgtcgcgg cgcgccaggc ggactgattt tccagagcat
    11341 ttgcggcagc gagaagggct taaaagagtt cggtgtcgag ctggcaatgc tcgacgaagc
    11401 gcgggcagtg ggggcggagt tcaaccgcat cgccggggaa aactgcctgt actttgaaac
    11461 cggacagggc tcggcgctgt cggctggtgc gaactttggt gccgaccagg tgacgatgga
    11521 agcgcgtaac tacgggctgg ctcgctacta cgatccgttc ctggtgaaca ccgtggtggg
    11581 ctttatcggg ccggagtatc tctacaacga caggcagatt atccgcgccg gtctcgaaga
    11641 tcactttatg ggcaagctga gcggcatctc gatgggctgc gactgctgct ataccaacca
    11701 tgccgacgcc gaccagaacc ttaacgaaaa cctgatgatt ctgctcgcca ctgccggctg
    11761 taactacatc atggggatgc cgctcggcga cgacatcatg ctcaactacc agactaccgc
    11821 tttccacgat accgccaccg tccgtcagtt gctgaattta cggccgtcgc cggagtttga
    11881 acgctggctg gaaacgatgg gcattatggc aaacggtcgt ctgaccaaac gggcgggcga
    11941 tccgtcactg ttcttctgat gacgcgggga taacaccatg gatcaaaaac agattgaaga
    12001 aattgtacgt agcgtgatgg cgtcaatggg acaggacgta ccgcagcccg tcgcgccgtc
    12061 aacgcaggaa ggcgcaaagc cgcagtgcgc cgcgccgacg gtgaccgaaa gctgcgcgct
    12121 ggatttaggt tccgcagagg caaaagcctg gattggcgtc gagaatccgc atcgtgcgga
    12181 cgtgctgacc gaactgcgtc gcagtactgc ggcacgcgtc tgtacgggtc gtgccgggcc
    12241 gcgtccgcgc acccaggcgc tgttgcgctt cctggcggat cactcccgtt cgaaagacac
    12301 cgtgctcaaa gaagtgccgg aagagtgggg caaagcgcaa gggctgctgg aagtacgttc
    12361 ggagatcagc gacaaaaacc tgtacctgac gcgcccggat atggggcgtc gcctgagccc
    12421 ggaagccatt gacgcgctga agtcgcagtg cgtgatgaac ccggatgtgc aggtagtggt
    12481 ctccgatggc ctctctacgg atgcgatcac cgccaactat gaagagatcc tgccgccgct
    12541 gcttgccggt ctgaagcagg ccgggctgaa cgtcggcacg ccgttctttg tgcgctatgg
    12601 ccgcgtgaag attgaagatc agattggcga aattctcggc gcgaaggtcg tcatcctgct
    12661 ggtgggcgaa cgtccggggc tggggcagtc ggaaagcctc tcctgctacg ccgtctattc
    12721 cccgcgcgtg gcgaccaccg tcgaggccga cagaacctgt atttcaaaca ttcatcaggg
    12781 ggggacgccg ccagtagaag ctgccgccgt gattgtggat ttggccaaac ggatgctgga
    12841 gcagaaagcg tccggcatca acatgacccg ttaaggagac atcatgcctg cattagattt
    12901 gattcgacct tcagtgactg ccatgcgcgt gattgcctcc gtgaatgacg gctttgcgcg
    12961 ggaacttaaa ttaccgccac atatacgtag tctcggactc atcacggcag attctgatga
    13021 tgtgacctat attgccgctg acgaagcgac caaacaggcg atggtggaag tagtctatgg
    13081 ccgctccctc tatgccgggg cggctcacgg gccgtcgcct accgccggtg aagtgttgat
    13141 tatgctgggc ggaccgaacc cggcggaagt gcgcgccggt ctggatgcga tggtcgccag
    13201 tattgaaaac ggcgcggcgt tccagtgggc gaacgatgcg gaaaataccg cgttcctggc
    13261 gcatgtggtt tcgcgtaccg gctcgtacct ctcgtctacc gcaggtatcg cgctgggcga
    13321 tccaatggcc tacctggtgg cgccgccgct ggaagcgaca ttcggcattg acgcggcgat
    13381 gaaatccgct gacgttcaac tggtgactta cgtgccgccg ccgtcggaaa ccaactattc
    13441 ggccgcgttt ttaacgggaa gccaggccgc gtgtaaagcc gcctgcaacg cctttaccga
    13501 cgccgtgctg gatatcgccc gtaaccctgt ccagcgtgcg taacggaggc tgccaatgat
    13561 caatgccctg ggattactgg aagtggacgg aatggtcgcc gccgtcgatg cggcggatgc
    13621 catgctgaaa gcggccaacg tgcgtttgct cagtcaccaa gtgctcgacc ctggcaggct
    13681 cacgctggtg gtggagggcg atctggcggc gtgtcgtgcg gcgctagatg ccggaagcgc
    13741 cgccgcgcag cacacaggcc gtgtgattag tcgcaaagaa attggtcgtc cggaagagga
    13801 cacccagtgg ctgattggcg ggtttgcgcg tgcgacaacg ccgactgaga aagcgcccca
    13861 ggtacccgca acgcctgagt tcgctgaagc gttactggcg ctgctggcat cagtacgcca
    13921 gggaatgacg gcgggagagg tggccgcgca ttttggctgg ccgctggagc aggccagaaa
    13981 cgtgctggaa caactctttt ctgacggagc gttgcgtaaa cgcagtagtc gctatcgcat
    14041 caaaaattaa tctgtcggag ggccgggcgt cctggcgggc gtccggcata gaagatcatg
    14101 aaaaagaccc gtacagcgaa tttgcaccat ctttatcatg aagcgttacc cgaagacgtt
    14161 aaacttacgc ccagagtcga ggtggacaat gttcatcagc gacggacgac ggatgtctat
    14221 gaacatgctc tgactatcac cgcctggcag cagatctacg atcagttaca cctgggtaaa
    14281 tttcatggcg agttcacgga aatcctgctt gatgagattc aggtgttccg tgaatacacc
    14341 ggcctggcgc tgcgtcagtc gtgtctggtt tggccaaact ctttctggtt tggtattccg
    14401 gcgacgcgcg gcgaacaggg atttattggc gcgcaggggc tcggcagcgc cgagattgcc
    14461 acccgaccgg gaggcaccga gtttgaactg agcacgccgg atgattacac cattctgggc
    14521 gtcgttatct cggaagatgt tatttcccgt caggccacgt ttttgcataa cccggaaagg
    14581 gtgctgcata tgctgcgtaa ccagttagcg ctggaggtaa aagagcagca taaagcggcg
    14641 ctgtggggct ttgtgcagca ggcgctggcc acctttagcg agagtcctga aaccctgcat
    14701 caacctgcgg tgcgtaaggt cttgagtgat aatttgttgc tggcgatggg cacgatgctg
    14761 gaagaggcga agccgattca tagcgccgaa agcatcagcc atcagggata tcgtaggcta
    14821 ctgtcgcggg cgcgggaata tgtgctggaa aatatgtcgg agccgctgac ggtgctcgac
    14881 ttatgtaacc agctacacgt aagccgtcgc acgctgcaaa atgcgtttca cgccattttg
    14941 ggcattggcc ccaatgcgtg gctgaaacgt attcgcctca atgcagtgcg ccgggagttg
    15001 attagcccgt ggtcgcagag caccacggtc agagatgccg cgatgcagtg gggattctgg
    15061 catctggggc agtttgccac cgattatcag caattatttg ccgaaaaacc gtcgttgacg
    15121 ctgcatcaac ggatgcggca atgggcttga tattgatggg taggctctcc ggttgctgat
    15181 aacgtgcgcg tgtcgggaat tgcccggtgg cggctggcgc cttaccgggc ctacggattc
    15241 gctgctgttt gtggttggta gcccggacaa ggcgcgccag cgccgcctcc ggggaagcgc
    15301 gcgcacaacg tgcaaaacag ttttgtcatc agatcatgag gatgagcgtt tatgtttgct
    15361 gataagacgt tgccgttgtt tggcaggagg ggcagataaa cccgtaaagc attccttccg
    15421 catattcctc ttcctcgata tcttcatagc ttagctgcgc aagaaacatc atcgtttgcg
    15481 cgcacgttgg gcacgtggga tagtctgtat cctgaaccca tgcgggatgg ccgccgagct
    15541 gtgagaaggt ggtgggtaaa aatatttcag cagcgaatag cggcaaacgg gattccccgg
    15601 ggtgcagaac atcaagcggt agcgttatcc agtcagagga attctccacc gccagcgtcg
    15661 agagcgcatt tttttcgtac catcgcggct ggccttgtgg atcgacggtg gcgaaaacgg
    15721 tgttatatgc cgtacaacac tgacaggtca gaatacgaat ttgaccgggc caaccctgcg
    15781 tgcttaggcc gacggcgctc ggcgcaacct caaacagatt gattagcggc agggaacagt
    15841 gtgggcagtt ttcaccatat tctgcaacgg cgcgaaaaac ggccggctgt tcaggtgcct
    15901 gttttaccag atgggtacat tgcgtaaagt aaagatcgcg cctgcggcca ttttcagtga
    15961 gctcccatcc cgcctggtga gcatagcgat gagggaggat atgaagtgaa gcactccacg
    16021 caggtggttc ctggcgccag cggttaaaat gctcaacgac aacctcatcg ccaatccagg
    16081 ccagggcgca aagaatgcca tcacggtttt cgtcatcggt ttcaaccttc tgcaaaagcg
    16141 cgtcgcgtac gtcaggcggc gcacggtgaa aaggtagggg tgaagagagc tccagttcct
    16201 cttcatttat tacttggcgc aggaaattat ccagattggc ctgggtaaat gccgccaggc
    16261 acagcgcaat ttcctgagct tcctcctgcc atccggaatc aaataattct tctgcataat
    16321 cgaccatgtc gcggctttca tcatcggaga gctttttgta aagctcatcg gtcggaatgg
    16381 ggcagggaat ccactcgatt aacggatcgt gttcccgggg ttcatgaacg agtttaagca
    16441 tttcaacagg gttggtaatg ccactgaacg cgtcgatcgt ttttctgttt ttccggatat
    16501 attcttcctg ctcttgccga tagcgcgcct ggacgcaggg catgcaatag ccctccgtgc
    16561 gggcagccgt tgctggcagg atgaaatgtg agcattgcgg gtttttacaa ggaatacgct
    16621 cgtccatgcg gtagtgctcc actgcaaatt ctacgagtgt ttactgtact gttttactaa
    16681 tgataacggc agcgggcggt tatccgaatt ctttatctac aatgaactcg tttatttcta
    16741 cgagcctgct tttattcaac ggccaaccgg ataggcgata aacaaaccgg ctatcgtcaa
    16801 aatacatgcc agtaggcata gcaagatgca gttaacgctt ttacgcggaa tatgaataat
    16861 aaagcagagt aatgctatca gggccatgac cacagggatg gtcaccatat tgataaccag
    16921 aagcacgatc agaccgaagc tcacccctcc gctatgaggg atgaatattc tttcttcaaa
    16981 atatatttct agcgtaatgg caagcaggca gccaataaaa cttataccca gatggggatg
    17041 ccatttggcg tcactggtta ctactttccg tgtatttgtt tgcattgttt tactttataa
    17101 ataagttaaa tccagtcgcg tacctgaata aactcgctca gcgccgcttc cgggctaccc
    17161 gcttccggct gccagtcgta ctcccagcgc accagcggcg gcatcgacat caggatagat
    17221 tcagtgcgcc cgccggtttg cagaccaaac agggtgcctc tgtcccatac cagattgaac
    17281 tccacgtagc gaccgcggcg ataaagttga aaattacgct cccgctctcc ccagaccatc
    17341 gctttgcgtc gttcgacaat cggtaaatac gcctcggtgt agccgttacc gaccgcctgc
    17401 ataaaagcaa aacagtggtc gaaatccggc gtattcaaat cgtcaaaaaa caggccgccg
    17461 ataccgcgct gctcgttacg atgcttgagg aaaaagtagt catcgcacca ctttttatag
    17521 cgcggataca catcgtcgcc aaacggctgg cacaggtcgc gggcggtgcg gtgccagtga
    17581 acggcatcct cttcaaagcc gtagtagggc gttaaatcga acccgccgcc aaaccaccac
    17641 accggatcgg cgcccggttt ttcggcaata aaaaagcgca cgttagcatg gctggtggga
    17701 atatacggat tgtgcggatg caccaccagc gatacgccca tcgcttcaaa actacgcccg
    17761 gccagttctg gccgatgtgc ggtggcggac gcgggcattg catcgccgtg aacgtgagag
    17821 aaattaacgc ccgcctgttc gaaaattccg ccgttgcgta atacccggct gcgtccgccg
    17881 ccgcccgctt cgcgtcgcca gctatcttcg ataaagtttg cgccatccac agcggataac
    17941 gtttggcaaa tatcatcctg caggcgtagc agaaactgtt ttacgtgatg tgcatcgggt
    18001 ttcatgatta ccgtttcttc gtgtgtgctt tctgattatc aaaccagtga aaataactga
    18061 tgatgccgtt ggcgatcgcc gtagcgattt tctggcgaaa cgccgtcgtg cccagcaggc
    18121 gttcttcttc cggattggta ataaacgagg tttcgaccag taccgacgga attgacggtg
    18181 attttagcac cacgaaagcc gcttgttcgg tagtgcggct gtgtaattta tgtatgggtt
    18241 tgattttctt gagaatatgc gaacccagcg tcagactgtt tttaatcgta tcggtttgca
    18301 ccagatcaaa caaaacttgt tgtaatagat gatcccggtc agtggctttt ttacccgcca
    18361 cttcgtccgc gcggttttca cgctcggaga gatacttcgc catggcgcta ctggccccgc
    18421 ggttggaaag cgcaaaaacg gaagcgcccg ccgctttcgg attggtaaaa ccatcggcat
    18481 gaatagacat aaacagatcc gcgccgtgct tatgggcgat ttccacccga tcgtacagcg
    18541 gaataaaggt atcccctgtc cgggttaaac gcgcatcgat tccgtgattt cgcaaaatag
    18601 cgcgtacgtt tttggcaatt gccagtacga cgtgtttttc ctgagaaccg ttgcggccaa
    18661 tcgcgccggt atcgatgccg ccgtgtccgg ggtcgagcat caccaaccgt ttactgccgg
    18721 tttttttggt tttgggtttg ctgtgaccat tactggtttt tagcgtttct tctttggcta
    18781 ttgcgtgcga catacctgac agcgtcaggg ccgccagacc tgttttgagt acctggcggc
    18841 gcgatgtgag agtttttagg agtttaaaag tgctcatacg gcctgagttg tgaaaattaa
    18901 gttcaagatg ttatatcgta tcgcgtaatc cgttacgacg gttggtgatg agaattgttt
    18961 tacttttcat ttcaatacgt gacacatcgc cattatgcca ttttttccgc tacatcgcgt
    19021 cagatattgg ctgaatcaga tgtttgcgcc ataatcttgg tttttccacc cgaaaaggca
    19081 acgaatacca tggaaatacg cgtttttcgc caggaagatt tcgaagaggt gattaccctc
    19141 tgggagcgtt gcgacctgct gcgtccatgg aacgatcctg aaatggatat tgaacgcaag
    19201 gtgaatcacg atgtcagctt gttcctcgtt gcggaagtta gcggcgaagt cgtcggtacg
    19261 gtaatgggcg gttatgacgg gcatcgcggc tcggcgtatt acctgggcgt tcacccggag
    19321 ttccgcgggc gcggcattgc gaatgcgctg cttaaccggc tggaaaaaaa actcatcgcc
    19381 cgcgggtgtc cgaaaatcca aattatggtg cgtgatgata acgacgttgt gctgggcatg
    19441 tatgaacgtc tggggtatga gcattctgac gccctaagtt tgggtaaacg cctgattgaa
    19501 gatgaagagt actgagtttc atccagccga ttatgatgta cacggatgtt tacgcctgcc
    19561 gtttctgttc tggtgcgtac tgctacttca ggcgcgcgcc tgggtactct ttgtcattgc
    19621 cggttcatcc cgtggacagg gtaatacttt gttaaacttt ttttatcccg accatgataa
    19681 tttttggctg gggctgttgc ccggcgttcc ggcggtagtg gcgtttttac tcagcgggcg
    19741 gcgtgaagcg gttcctggtg tgtggcgctg gctgcgcgga ctcctgatcc tcgctcaact
    19801 ggtgtcgttg tgctggctgc cggtgatgtg gctgggtggc gacccggtca acggcgtcgg
    19861 gctggcgctg ctgctggcgg acatcgtcgc gctgatctgg ctgttaacca atcaacgttt
    19921 gcgtgcctgt ttttcccttg agaaagaata acggcacttt ttggcgaacc cgtactccaa
    19981 ccaacgttaa ttaataaaag aaaggaagtg agatgaaatc gctgcgtttg actttactcg
    20041 cactgccgct ggcgctgacc ggctgctcga cgctctcctc ggtcaactgg tctgccgcaa
    20101 atccatggaa ctggtttggt tcctcgacag aagtcactga gcaaggcgtg ggagcgctga
    20161 ccgccgccac gccgctggaa gagccggcta ttgcagaggc attagatggc gattatcgcc
    20221 tgcgtagcgg tatgaaaacc gataacggca acgtggtgcg ctttttcgaa gcgatgaagg
    20281 gcgacagcgt cgcgatggtg atcaacggcg agcagggaac cgtgagccgt attgatgtgc
    20341 tggacagcga tatcccaacc gccgcggggg gcaaaatcgg tacgccgttt agcgaccttt
    20401 acagcaaagc gtttggtcac tgcgagccgg tttccagcga tagccatacc agcgtcgaat
    20461 gtaaagccga gggaagtcag catattagct atgttttctc cggcgagtgg agcggaccgg
    20521 aaggcttaat gcctcctgat gacgtcttaa aaaactggga cgtgcgcaaa attatctggc
    20581 gtcgttaatt tgcgcctgaa caaaccgctt cgcttaaaaa caaggtaaaa taacctccat
    20641 taatgccacg actgcgtggc attctcattt tcaggaggaa tcatgtctca ggttcaaagt
    20701 ggcattttgc cggaacattg ccgtgcggca atttggattg aagccaatgt aaaaggcgac
    20761 ctggacgccc tgcgcgcggc cagcagaaca tttgccgata aactggcgac cttcgaagtc
    20821 aaatttccgg acgcccatct tggggccgtt gtggcgtttg gcaacaatac ctggcgtgcc
    20881 ctgagtggcg gcgtcggggc ggaagaactg aaagatttta ttccttatgg taaagggctg
    20941 gcgccagcca cgcagtatga cgtgctgatc catatccttt ccctgcgcca cgatgtgaat
    21001 ttttctgttg ctcaggcggc gatggaagcc ttcggcgact gtatcgacgt gaaagaagaa
    21061 gttcacggct tccgttgggt ggaagaacgc gatctgagcg gctttgtcga cgggacagag
    21121 aacccggcgg gcgaagagac gcgtcgtgaa gtggcggtga tcaaagatgg cgtggatgcc
    21181 ggcggcagtt atgtgttcgt gcagcgttgg gaacacaatc tcaagcaact taaccggatg
    21241 agtattcacg atcaggagat gatgatcggg cgtaccaaag aagccaatga agagattgac
    21301 ggcgatgcgc gtccggcaac atctcacctg agccgcgtcg atctcaaaga agatggcaaa
    21361 gggctgaaga ttgtgcgtca gagcctgcca tacggcaccg ccagcggtac tcatggtctc
    21421 tatttctgcg cttactgcgc acgcctgcac aatatcgaac agcagcttct gagtatgttc
    21481 ggcgataccg acggtaaacg cgacgcaatg ctgcgcttca ccaaaccggt gactggcggc
    21541 tactattttg cgccgtcgct ggatcgcctg ttagcgctat aagtaaaacc ctgtcggatg
    21601 gcagcgcaaa cgctttattc gacctacgat tggtaggcct gacaagcgcc gcgccatcag
    21661 gcagaacagc ataaaaatgc ccatccccgc ctccgcgggg atttttttac ctaatattta
    21721 cctgaattag tgagctattc ctcagcactt atttgttatt actgtatttt cagtgttaat
    21781 ggagtgtaag actccatatt caaaaggaga cattgaaaat gggtaaactc acgggcaaga
    21841 cagcattgat tacgggcgca tcgcagggca ttggcgaagg gatcgctcgc gtattcgcac
    21901 gccacggcgc gaacttaatc ttgctggata tctccgatga gattgaaaag ctggcggatg
    21961 agctgggcgg gcgcgggcat cgctgtactg ccgttaaagc cgacgtcaga gattttgctt
    22021 cggtgcaggc ggcggttgcg cgcgccaaag agactgaagg tagaattgat attttggtga
    22081 ataacgctgg cgtgtgccgt ctgggcaact tcctcgatat gagtgaagaa gatcgcgatt
    22141 tccacattga tattaatatt aaaggtgtct ggaacgtcac caaagccgtc ctgccggaga
    22201 tgatcaaacg taaagatggc cgcattgtga tgatgtcttc cgtcacggga gatatggtgg
    22261 cggacccggg tgaaacggcc tatgcgctgt caaaagccgc cattgtcggt ttaaccaaat
    22321 cgctggcggt agagtacgcg cagtccggta ttcgtgtgaa tgccatttgc cccggttatg
    22381 taagaacgcc gatggcggaa agcattgccc gtcagtctaa ccctgacgat ccggaatcgg
    22441 tattaacgga aatggcaaaa gccattccgc tacgccgtct tgccgatccg ctggaagtag
    22501 gggaactggc ggcatttctg gcttccgatg agtccagcta tcttaccgga acgcaaaacg
    22561 tcattgatgg cggcagtacc ctgcctgaaa gcgtaagcgt aggcgtctga ttgatgccgg
    22621 tctcctcctc acgccgcgtg gggagggatt ctcttattcc cttttcaact ttcaaatcat
    22681 caaacggtat ataaaaccgt tactccttta gcgctggtta taaatatgat gaccataaga
    22741 aagtcattaa atttataagg gtgcgcaatg gccgttaact tactgaaaaa gagactcctg
    22801 acgctggcag caatgctgtt actggcaggg caggcgcagg caacggagct gctgaacagc
    22861 tcatacgatg tctcccgcga gctgtttgcc gcccttaacc cgccgtttga gcaacaatgg
    22921 gcgaaggata acggcggcga taagctgacg attaagcagt ctcatgccgg gtcatcaaaa
    22981 caggcgctgg cgattttgca gggactgaag gcagacgtcg tgacctacaa tcaggtgacc
    23041 gacgtacaga ttcttcatga taaaggcaaa ctgatccctg ccgactggca aagccgtctg
    23101 ccgaacaaca gttcgccatt ctattccact atgggcttcc tagtgcgcaa ggggaacccg
    23161 aaaaatattc acgactggag cgatcttgta cgttccgacg tgaagctgat tttccctaac
    23221 ccgaaaacct ccggcaacgc ccgttacacg tatctggcgg catggggcgc ggcggataac
    23281 gcggacggcg gcgataaagc caaaaccgaa cagtttatga cccagttcct gaaaaacgtc
    23341 gaagtgtttg ataccggcgg tcgcggcgct acgactacct ttgccgagcg tggtctgggc
    23401 gatgtgctga ttagttttga atcggaagtg aacaacatcc gcaaacaata tgaagcccag
    23461 ggatttgaag tggtgatccc gaaaacgaac attcttgctg aattcccggt tgcctgggtg
    23521 gataaatacg tgaaggccaa cggcacagaa aaagccgcca aagcttacct gaactggctg
    23581 tatagcccgc aggcgcagac catcattacc cattactact accgcgtgaa taacccggaa
    23641 atcatgggca agcaagcaga taaattcccg caaaccggac tgttccgcgt ggaagacaag
    23701 tttggcacgt ggcctgaggt gatgaaaacg cactttgcca gcggcggcga gctggacaaa
    23761 ctgttggcgg cggggcgtaa gtaatgcttg ccgtttcttc ccgacgcgtg ctgcccggct
    23821 ttacgttaag cctcggcacc agtttgctgt ttgtctgcct gatcctgctg ttgccgttga
    23881 gcgcgctggt gatgcagctc tcacagatga gctggtcgca atactgggat gtcgtgacca
    23941 acccacaggt ggtggctgct tataaagtga cgctgctggc ggcatttgtg gcgtcgattt
    24001 ttaatggcgt gtttggcctg ctgatggcgt ggattttaac ccgctaccgt tttccagggc
    24061 gcacgttact ggatgcgctg atggatctgc catttgcgct gccgacagcg gtggcggggt
    24121 taacgctggc ctcgctgttc tcagtgaacg gtttctacgg tcagtttctt gcgcagtttg
    24181 atatcaaagt gacctatacc tggctcggta ttgcggtggc gatggccttt accagcattc
    24241 catttgtggt gcgcaccgtc cagccggtac tggaagagct ggggccggaa tatgaagaag
    24301 cggcacaaac gctgggggcc acccgcctgc aaagttttcg caaagtcgtg ctgcctgagc
    24361 tgtcgcctgc gctgattgcc ggcgtggcgc tctcttttac ccgtagcctg ggcgagtttg
    24421 gcgcggtgat ttttatcgcc ggaaatatcg cctggaaaac agaagtgacc tcgctgatga
    24481 tttttgtgcg tttgcaggag tttgattacc cagctgccag cgccattgcc tcggtgatcc
    24541 ttgcggcatc actgctgctg ctgttctcaa ttaacactct gcaaagtcgc tttggtcgac
    24601 gtgtggtagg tcattaatgg cggaagtgac tcaattgaag cgatacgacg tcccccgtat
    24661 taactgggga aaatggtttt tgattggcgt cgggatgctc gtttcggcct ttatcctgct
    24721 ggtgccgatg atttacatct tcgtgcaggc gttcagcaaa gggttaatgc cggtactgca
    24781 aaatctggcc gatccggaca tgctgcacgc catctggctg acggtgttga ttgccttgat
    24841 cgcagtgccg atgaatctgg tgttcggtat tctgctggcg tggctggtga cgcgctttaa
    24901 cttccccgga cgtcagctac tgctgaccct gctggatatt ccctttgccg tctcaccggt
    24961 ggtggccggt ctggtttatc tgttgtttta tggttccaac ggcccgttgg gcggctggct
    25021 ggatgagcat aatttgcaaa tgatgttctc ctggccgggg atggtactgg tcactatttt
    25081 tgtcacctgc ccgtttgtgg tgcgcgaact ggtgccagtg atgctcagcc agggcagcca
    25141 ggaagatgag gcggcgattt tactgggcgc atccggctgg caaatgtttc gccgcgtgac
    25201 gttgccgaat attcgctggg cgctactcta cggcgtggta ttaaccaacg cccgcgcgat
    25261 tggcgagttt ggcgcggtgt cggtggtgtc cggctcgatt cgcggcgaaa cgttatcgct
    25321 accgttacag attgaattac tggagcagga ctacaacacc gtcggctcct ttaccgccgc
    25381 cgcattgttg acgctaatgg cgattattac cctgtttttg aagagcatgt tgcaatggcg
    25441 tctggagaat caggaaaaac gcgcgcaaca ggaggaaaat catgagcatt gagatcgcca
    25501 gaattaagaa atcgtttggt cgcactcagg tactgaatga tatctcgctg gatattcctt
    25561 ccggccagat ggttgccttg ttggggccgt ctggttccgg caaaacgacg ctgctgcgca
    25621 ttattgccgg gctggaacat cagtccagcg gccatattcg tttccacggt acggacgtta
    25681 gccgcctgca cgcgcgtgag cgtaaagtcg gttttgtgtt tcagcactat gcgctgtttc
    25741 gccatatgac ggtgtttgac aacatcgctt ttggcctgac ggtgctgccg cgacgcgacc
    25801 gcccaactgc ggcggctatt aaaacgaaag tgacgcaatt gctggagatg gtgcaactgg
    25861 cgcacctcgc ggatcgcttc cccgcccagc tttccggcgg acaaaaacag cgcgtggcgc
    25921 tggcgcgcgc gcttgccgta gaaccgcaaa ttctactgct ggatgaaccg tttggcgcgc
    25981 tggatgccca ggtacgtaaa gagttacgtc gctggttgcg ccagctacat gaagaactga
    26041 aattcaccag cgtctttgtc acccacgatc aggaagaagc gacggaagtg gcggatcggg
    26101 tggtggtaat gagtcagggc aatatcgaac aggctgacgc gccggatcgg gtgtggcgtg
    26161 aaccggcaac ccgcttcgta ctggagttta tgggcgaggt gaaccgcctg acaggcaccg
    26221 tccgcggcgg gcagtttcac gttggcgcgc atcgctggcc gctgggttat acgcccgcgt
    26281 accaagggcc ggtcgatctg ttcctgcgtc cgtgggaggt ggatatcagc cgccgcacca
    26341 gcctggattc tccgctacca gtacaggtca ttgaggcaag cccgaaaggt cactatacac
    26401 agttagtggt acagccgctg gggtggtatc acgatccgct gacggtggtg atggcgggtg
    26461 acgacgtccc gcagcgcggc gagcgtttgt ttgtcggctt acagaacgca cgtctctatc
    26521 atggcgacca gcgtattgag ccccatgagg cgcttgctct tgcggagtct gcctgatagg
    26581 ttaatttgca tagttatcgc ccggtggcgc ttcgcttacc gggcctacag cgtatatcgt
    26641 gattttgtag gccgggtaag cacagcgcca cccggcattt ttattgagct gaaaacgtga
    26701 atacattaga acaaaccatc ggcaatacgc cgctggtcaa attacaacgg ctggggccgg
    26761 ataacggcag tgaaatctgg gtcaagctgg aaggcaataa tccggcagga tcggtgaaag
    26821 atcgcgcggc gctatcgatg attgtcgagg cggaaaagcg cggggaaatt aaaccgggcg
    26881 atgccctgat tgaagcgacc agcggcaaca ctggcattgc gctggcgatg atcgccgcgc
    26941 tgaaaggtta tcgcatgaag ctgttgatgc cggacaacat gagccaggag cgtcgggcgg
    27001 caatgcgggc ctatggcgcg gaactgattc tggtcactaa agagcaggga atggaagggg
    27061 cgcgcgattt agcgctcgct atgtctgagc gcggagaagg taaactgctc gatcagttta
    27121 ataatcctga taatccctac gcccactaca cgaccaccgg cccggaaatc tggcggcaaa
    27181 cgtcaggtcg catcacccat tttgtctcca gcatgggcac gaccggcacc attaccggcg
    27241 tgtcgcgttt tctgcgcgag caggaaaaaa cggtcaccat cgttggcctg caaccggaag
    27301 agggcagcag tattccgggc attcgccgct ggcctacgga atatatgccg ggcatattta
    27361 acgcctcgct ggtggatgag gtgctggata ttcatcagaa tgatgccgaa aacaccatgc
    27421 gtgaactggc ggttcgtgaa gggattttct gcggcgtcag ctccggcggc gcggtagcgg
    27481 gcgcgttacg cgtcgcacga gccacgcccg gcgcgatagt ggtggcgatc atctgcgatc
    27541 gcggcgaccg ttacttgtct accggcgtgt ttggtgaaga gcatttcagc cagggggcag
    27601 ggatttaaac gaggtgccat cgtcgtatga cacccgtgtg ttatagcgtt ttatccgttt
    27661 ccgcaataag tgcatgtaaa taaggctgcg cgttttcatc gcttttacca ggaattttaa
    27721 cgatataggg ttttccggtg atggacgacg acgacgcgac tttatcgata aactgttcag
    27781 cggtgtcgat acgattgcgc gtgttaccca gttttaagcg caggtgcgat acggcttcct
    27841 cgcagttatg cgcatcaccg ttacgaacga aggtcagatc ctttttctgc gccagcacat
    27901 taagcatggc gttaatgcgc gcttcttcat gggcgtttag cttcgcccag gcggggaggg
    27961 tcagcaggag cgcgacgacg gcgcagacaa ttttcttcat ggtaaaatcc tttttcatgc
    28021 aataatcact gcacctcaga ccgttagccg ggtaataagt tgcactcctg gtgtggttat
    28081 ttctgtgagt gcgccagcgt gagttcatcc agaaaacgcc acagcttttc attcatctgc
    28141 tgataattcc atgcgcgcat ctcggcgacc gagcggataa aacgcttccc ttgcgcgtcg
    28201 gccagctcct gctgcgaatg ttggattaat ccttcaaccg cctcgacggt aaattccata
    28261 tgacactgga agccgtagac aaaattgccg tactgcacga tttgtcgcgg gcagccctca
    28321 ctggtagcaa gaattatcgc ctggtcggtt aaccccggca tgtcgttatg ccagtgaccg
    28381 acgataagcg gggagccgaa atggttgaac agcgggtgct gttggcctgc ctcggtcagg
    28441 acgattgggt agtgaccgat ctctttttcc ggactttggc acaccttggc gcccagcgct
    28501 tcgccaatta actgcgagcc caaacagatc cccaccacga tttttcgtgc cgaaatcgcc
    28561 tggttaatca gatgttgctc ggcctgagaa tcaaagtacg ggcactcttc gcgggtggtg
    28621 cgcggcgact gcggaccgcc aaataccacg agcatatcga actcatctgc attgggcggt
    28681 agcgcttctc cggcatagac gcgcgaccat gaaatggtat aaccgcgatc ttcagcccat
    28741 ttcagataag cgccagcgga ttcaaacgac tcatggataa caaaatgaac tcgcacgtta
    28801 ttttctcctg ttagcgattt agcgcctgat ggatatcagc cgccagcgtg ttgatctcgc
    28861 cgtcatttaa tgtcgacagc gtgatacgta gaccgtgaga cggcgcgctt acgccaaagg
    28921 cttcgccctc acgtaccagc cagccggatt ttgccagcgt aaacgcggta gcctggctat
    28981 gggtgtccag cgggagccag gcattcacgc cgtcgccggg agaaatggcg atgccatatt
    29041 gctgtagggc gcgggccagt ttttgttgcc gggtggcgta aaacagccgc gtttgcgcca
    29101 gcctgtgctg atactcaggg tcggtcaggc aggcgtagac cagatcctgt aacagatggc
    29161 tgacccactg actaccggca tttagccgca gccgaagttt tgccgaggtc gagctgtcgc
    29221 tggcgacaat agcaagacgt aaatcggggc cgagggcttt ggaaacggag cgtatcaccg
    29281 cccagtgttg cgttgtctgc gcaataaccg gctgccaggg cgacgaagaa agcagggcga
    29341 agtgatcgtc gataatgacc agtacctgag ggtaacgcgc cagtatattt tgcagcgcag
    29401 cggcacggcg agcgctcagg ctacagccgg tagggttgtg tgcgcgcggc gttaagatca
    29461 ctgcccgcgc gccctggttt agcgcctgct ccagcttttc aggctgcatt ccttcgctat
    29521 ccacactgac cgggctggcg ctaaaaccgg catagcgcag catattgata ctgcttaaaa
    29581 aacagggatc ttccaccgca acgctgtcgc ccggcagcag atgcgcgcaa agcagtcttt
    29641 cgatagcgtc gatagctccg ctggtgatat caatttcgcc tgcgacgggg gtggcatccc
    29701 gtagccagcg cgccgcccag gcgtgtagtt caggggaaac gggcgcatcg ccgtagagat
    29761 gcggcgtgcg gctgagacgg gcaaaataac ggctaaggtc aggcagacgc tgcggatcgg
    29821 gattgccgcc ggaaaggtcg tgcagaggcg tatgcggatc gccgccttcc aacgctacgg
    29881 gagacggact gcctttaatc accgtcccat tgcggcctaa actttgcgcc agtcccgccg
    29941 ttatcagccg tttatacgcc gctgcgacgg tattgcggtt cacctttaat tcgcttgcca
    30001 gctcccgtac cggcgggagc gaatccttcg cccgtaacgt gccggcgata atgtgttgac
    30061 ggatactgtc aaaaatttcg ttagcggttt ttccgtcgat cattattgac ctatgacaaa
    30121 atgaatttta gcatatgaca atgataatga ggcggtagcc tgctgtccag cgagaggaaa
    30181 attttatggg acaagagagt gatattcagt cagtgctctt cgacgacaac catcgggcgt
    30241 tacagaccga tatcgtcgcc gtccagtcac aggttgtgta cggcagcgta ggcaacagta
    30301 tcgctgttcc ggccattaaa gcgcagggat tacgcgtgac ggcggtcccg acggtgttgt
    30361 tcagcaatac gccgcactat aaaacgtttt atggcggcat tattcccgcc gagtggtttg
    30421 caggctacct tacggcgttg aatgagcgcg atgcgctacg tgaattaaaa gcgattacca
    30481 ccggttacat gggcagcgca gaccaaattg tcttgctttc gaagtggcta atggcgatcc
    30541 gggcttcgca tccggaggtg tgtattcttg ttgatcccgt cattggcgat accgacagtg
    30601 gaatgtatgt gcaggcggaa attccgcagg cttatcgcac acatttgttg ccgcaggcgc
    30661 aggggctaac gccgaacgta tttgagctgg agatgctgag tggtaaaccg tgtcgcacgc
    30721 tggaagaggc ggtggcggcg gcgcaatcgc tgctttccga tacgctgaaa tgggtggtta
    30781 tcaccagcgc gccgggcgaa tctctggaga ccataacggt tgccgtcgtt accgcgcagg
    30841 tcgtggaggt ctttgcccat ccgcgggtgg cgacggagtt aaaagggacg ggagatctct
    30901 tctgcgccga gctggtcagc ggtattgtgc agggaaaaaa actgacgacc gcggcaaaag
    30961 atgcggcgca gcgcgtgctg gaggtgatga cctggacaca gcagtgtggc tgtgatgagt
    31021 taattctgcc gccggcaggg gaggcgcgat gaagagttat cggctggtgg ttcgccagca
    31081 ggggcgtatc gtggggcatt ttgaaacgag cgggctggac gcgctggaag atatctgcgt
    31141 ggcgcgagcg atgtttggca tcactggcgg ctatcagtgc gagttgcaag tgtccgattc
    31201 cgaacgcagg atactggaga gtggcccgga tgggatgaag atcctgatgc gcgagaagtg
    31261 ctttcgcccg gtgacctcgc agttgtaacc cgtggattgg cgctgaaatg ttcgcaacct
    31321 tgtaggcctg ataagcgtag cgccatcagg cagtgcgccg caccatcgcc ggatggcggc
    31381 gcaagtacag gcaaaaaaaa tggcgcccaa aggcgccatt cttcactgcg gcaagaatta
    31441 cttcttaatg cggataaccg gagtttcacc cacggtcacg ctaccggaca gtttgatcag
    31501 ttctttgatt tcatccatgt tggagataac aaccggagtc agggtagact tggctttttc
    31561 ttccagcaac ggcagatcga actcgatgac cggatcgcca actttcacgc gctgaccttc
    31621 ttcagcaata cgcttgaagc cttcgccttt cagctcaacg gtgtcgatac cgaagtgaac
    31681 gaacagctca atgccgctat cggattcgat agagaacgca tggttggttt caaagatttt
    31741 gccgatggta ccgtcaacag gggcgaccat tttgttaccg gttggtttga tagcgatgcc
    31801 atcaccaacg attttttcag caaaaactac atccggcacg tcttcgatgt tgacgatctc
    31861 gccagagagc ggggcaacaa tctcaatagt tccggtgtct ttcttatcat cagaaaccag
    31921 agattttagt ttatcgaaca aacccatgat cttctcctaa gcagtaaatt gggccgcatc
    31981 tcgtggatta gcagattgtt ttttcttcaa tgaacttgtt aaccagcgtc attaactcgt
    32041 ccgttgtcgg ttgagcaaga gcctgctctg ctaacacctt cgcatcttcg aagttcgtgt
    32101 tacggataat cttcttaatg cgcgggatag aaatggcgct catagagaat tcgtccagac
    32161 ccatccccag caacagaagt gtagcacgtt cgtcgcctgc aagctcacca cacatgccag
    32221 tccatttacc ttctgcatga gaagcatcaa taacttgctt gatcaagttc agtacggacg
    32281 gtgacattgg ctggtaaagg tgtgaaatca tatcattacc acggtcaact gccagggtgt
    32341 actgcgttaa atcattggtg ccgatactaa agaaatcaac ttctttggct aaatgacgcg
    32401 caattgtcgc cgcagccggt gtttccacca tcacgccaat ctcaatgctt tcgtcaaatg
    32461 ctttaccttc gtcacgcagt tcctgtttgt agatttcaat ctctttgcgc agcgcgcgaa
    32521 cttcttcaac agagatgatc atcgggaaca taatgcgcaa tttaccgaaa gcggaggcac
    32581 gcagaatcgc gcgaacctgg tcacgcagga tctctttgcg atccatggcg atacgcacgg
    32641 cgcgccagcc caggaacggg ttctcttctt tcgggaagtt catgtatggc agctctttgt
    32701 cgccgccaat gtccatggta cggacgataa ccgcctgcga gccgcacgct tcagcgaccg
    32761 ctttataggc ggcaaactgc tcttcttccg tcggcagcgc gtcgcgatcc atgaacagga
    32821 attcagtacg atacagacca acgccttccg cgccgttacg ctcagcgcct tcaacgtcac
    32881 gaacggtacc gatgttggcg caaacttcaa cctgatgtcc atccagcgtg attgccggca
    32941 gatctttcag ttttgcgagt tccgctttct cggtcgcaac ctgctcctgg acggcgcgca
    33001 gttgctcaat aacatcgttg gtcgggttga cgtaaacctg gttgtttacg gcatccagaa
    33061 tcagatagtc gccgtttttc acctgagcgg tgacgctacc ggtacctacg atcgctggca
    33121 gttccagaga acgcgccatg atggaggtat gagacgtgcg tccgcccgcg tcggtgatga
    33181 agcccagcac tttctgcagg ttcagctgtg cggtttctga cggcgtcagg tcagcggcaa
    33241 ccaggataac ttcttcctga atcgcgctca gatcgataat ggccagaccc aggatgttgc
    33301 gcagcaggcg cttaccgata tcacgtacgt cagccgcacg ctctttcagg tattcgtcat
    33361 ccagttcttc cagggcagtg gcctgacctt cgataacttc atgtgcggct gcgtcagccg
    33421 tcatgtgctt atctttaatc agggctatga tttcctgctc cagctcctca tcttcgagca
    33481 gcataatatg cccttcaaag atggcttctt tttcttcacc gaacgtttca ccagcttttg
    33541 tcttgatcgc ttccagttgc gcagatgcct tggcacgacc gctcagaaaa cgttcaactt
    33601 cctgatcaac cttgtcggca gaaatttttt tccggtcaat gacgatttcg tcttctttca
    33661 gcagcagtgc tttgccgaaa gcgatacccg gggatgctaa aatgcctgaa atcataaccc
    33721 taccttactt gtgactgatt tttaaaagaa cccggaaaaa aacttactcg agttccgcca
    33781 tcagtttgac cagatgttca accgctttct gctcatcttc accttctgcg gagatggtga
    33841 cgacggtgcc ttgagtcagg cccagagtct gcagtttaaa caggcttttc gcgctggcgc
    33901 ttttgccgtt ggaagtcaca gtaatctcag aagtgaagcc ttttgcttct ttaacaaact
    33961 gagcagcagg gcgggtgtgc agaccgttcg gagcggtaat ggtaacttct tgctggaaca
    34021 ttgtatttcc ccaacttata ggtttagtgt tgtggaacta aagtctagcc tggcggctca
    34081 actttagcct gtattgttag cgccggcgta aacgggacgc gacacaaaag gtgttctacg
    34141 caatccgttg ctggcaactt atggccgctg acgtttcgct cgtcattaaa cattatgccg
    34201 cgaaaggaag agttgaacca aatcataaaa tcgattcagc taacgctttt cctgtaacga
    34261 ttaatttcgc gcatcaaaat aattagtctg gttaaatacc agttccggca gggtgaatca
    34321 atgccaggtg aggtgaaagt ttgaagcagg ccacaaaaaa gcacccaaaa aggtgctttt
    34381 ttacgcgttt ttaacatgct ggcatcactg ttgcagttct ttctcagtaa agagatcggc
    34441 gaacaacgcg gtgctcagat aacgctcacc tgatgagggt aggataacca caatattctt
    34501 attggtaaag ctttcatctt cctgcagctt aagcgctgca gcaaccgcgg cgccggaaga
    34561 aattcccgcc agaatacctt cctcttccat cagacggcgc gcggtagaaa tggcttcttc
    34621 attggtgatg ccaaccactt tatcaatcag tttcagatcc aggttgcccg ggatgaagcc
    34681 tgcgccgatg ccctgaattt tatgtgggcc cggtttgatc tcttcaccag ccagcgcctg
    34741 ggcgataacc ggggagtcag tgggttctac cgcaacggtg ataagatcgg ttttaccctt
    34801 cgtccctttg atataacgcg tgacgccggt taacgtaccg ccagtgccga cgccggagat
    34861 aaacacatcc acctgaccat cggtgtcttc ccagatttcc gggccggtgg ttttttcatg
    34921 gatttccggg ttggcagggt tgctgaactg ctggagcagg agatattttt gcggatcgct
    34981 ggcgacaatt tcttcggctt tctgaatagc gcctttcatc cctttcgccc cttcggtcag
    35041 caccagattc gcgcctaatg ctttgagtag cttgcggcgt tcaatgctca tggtttccgg
    35101 catggtcagg gtgagtttgt aaccgcgcgc ggcggcgaca tacgccagcg caataccggt
    35161 attgccgctg gtcggctcca ccagttccac gccaggtttc agtacgccac gcttttcggc
    35221 atcccaaatc atattggcgc cgatacggca cttgacgctg aagctcgggt tgcgcgactc
    35281 caccttcgcc agaatgcgtc cattaccgat acgattcagt cgaaccagcg gcgtatgacc
    35341 gatagtcagc gagttatctt cataaatctt actcatggcc tgtccttaac tgtatgaaat
    35401 tgggatacct tcccagcata ccttccagcc agatatgggg aagtaaggat ttcgcatatc
    35461 tatatgctga tggggaataa tggttatcag tatggaataa gagacagcat aagagcctat
    35521 cccattaggg ctattttact tgccattttg gtcttgggca gtgctcgcca aaacgcatta
    35581 gcgttttgaa cgccgcttgc ggcggcccga agggcgagcg tagcgagtca aacctcacgt
    35641 actacgtgta cgctccggtt tttgcgcgct
//
LOCUS       DAJVBX010000017        35180 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.017, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000017 DAJVBX010000000
VERSION     DAJVBX010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 35180)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35180)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35180
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.017"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            298..4758
                     /gene="gltB"
                     /locus_tag="OPV72_000785"
     CDS             298..4758
                     /gene="gltB"
                     /locus_tag="OPV72_000785"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001742510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase large subunit"
                     /protein_id="HCR9913158.1"
                     /translation="MLYDKSLEKDNCGFGLIAHIEGEPSHKVVRTAIHALARMQHRGA
                     ILADGKTGDGCGLLLQKPDRFFRIVAEERGWRLAKNYAVGMIFLNKDPELAAASRHIV
                     EEELQQETLSIVGWRDVPTNEGVLGEIALSSLPRIEQIFVNAPAGWRPRDMERRLFIA
                     RRRIEKRLQDDKDFYVCSLSNLVNIYKGLCMPADLPRFYLDLADLRLESAICLFHQRF
                     STNTVPRWPLAQPFRYLAHNGEINTITGNRQWARARTYKFQTPLIPDLQSAAPFVNET
                     GSDSSSLDNMLELLLAGGMDIIRAMRLLVPPAWQNNPDMDQDLRAFFDFNSMHMEPWD
                     GPAGIVMSDGRFAACNLDRNGLRPARYVITKDKLITCASEVGIWDYQPDEVVEKGRVG
                     PGELMVIDTRGGRILHSAETDDDLKSRHPYKAWMEKNVRRLVPFEELPDEEVGSRELD
                     DDLLASYQKQFNYSAEELDSVIRVLGENGQEAVGSMGDDTPFAVLSSQPRIIYDYFRQ
                     QFAQVTNPPIDPLREAHVMSLATSIGREMNVFCEAEGQAHRLSFKSPILLYSDFKQLT
                     TMSEHHYRADWLDITFDVTETTLDATVKALCDKAEQMVRNGTVLLVLSDRNIGKNRLP
                     VPAPMAVGAVQTRLVDQSLRCDANIIVETGSARDPHHFAVLLGFGATAIYPYLAYETL
                     GRLIDTQAIAKNYRTVMQNYRNGINKGLYKIMSKMGISTIASYRCSKLFEAVGLHDDV
                     VNLCFQGVVSRIGGASFDDFQQDLLNLSKRAWLARKPISPGGLLKYVHGGEYHAYNPD
                     VVRTLQQAVQSGEYSDYQEYAKLVNERPAATLRDLLAIHPDGEAVTIDEVEPASELFK
                     RFDTAAMSIGALSPEAHEALAEAMNSLGGNSNSGEGGEDPARYGTNKVSRIKQVASGR
                     FGVTPAYLVNADVIQIKVAQGAKPGEGGQLPGDKVTPYIAKLRYSVPGVTLISPPPHH
                     DIYSIEDLAQLIFDLKQVNPKAMISVKLVSEPGVGTIATGVAKAYADLITIAGYDGGT
                     GASPLSSVKYAGCPWELGLVETQQALVANGLRHKIRLQVDGGLKTGVDIIKAAILGAE
                     SFGFGTGPMVALGCKYLRICHLNNCATGVATQDEKLRKNHYHGLPFKVTNYFEFIARE
                     VRELMASLGVTRLVDLIGRTDLLKELEGFTAKQQKLALSRLLETAEPHPGKALYCTEN
                     NPPFDNGVLNAQLLQQAKPFVDARQSKTFWFDIRNTDRSVGASLSGYIAQTHGDQGLA
                     SDPIKAHFSGTAGQSFGVWNAGGVELYLTGDANDYVGKGMAGGLIAIRPPVGSAFLSH
                     KASIIGNTCLYGATGGRLYAAGRAGERFGVRNSGAITVVEGIGDNGCEYMTGGIVCVL
                     GKTGVNFGAGMTGGFAYVLDEDGEFRKRVNPELVEVLDVDSLAIHEEHLRGLITEHVQ
                     HTGSQRGEEILSRWSSFSTQFALVKPKSSDVKALLGHRSRSAAELRVQAQ"
     gene            4768..6186
                     /gene="gltD"
                     /locus_tag="OPV72_000786"
     CDS             4768..6186
                     /gene="gltD"
                     /locus_tag="OPV72_000786"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001540975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase subunit GltD"
                     /protein_id="HCR9913159.1"
                     /translation="MSQNVYQFIDLQRVDPPKKPLKLRKIEFVEIYEPFSEGQAKAQA
                     DRCLSCGNPYCEWKCPVHNYIPNWLKLANEGRIFEAAELSHQTNTLPEVCGRVCPQDR
                     LCEGSCTLHDEFGAVTIGNIERYINDKAFEMGWRPDMTGVRQTDKRVAIIGAGPAGLA
                     CADVLTRNGVKAVVFDRHPEIGGLLTFGIPAFKLEKEVMTRRREIFTGMGIEFKLNTE
                     VGRDVQLEDLLKDYDAVFLGVGTYQSMRGGLENEDADGVFDALPFLIANTKQIMGFGE
                     TSDEPYVSMEGKRVVVLGGGDTAMDCVRTSIRQGATHVTCAYRRDEENMPGSRREVKN
                     AREEGVEFQFNVQPLGIEVNANGKVSGVKMVRTEMGEPDAKGRRRAEIVAGSEHVVPA
                     DAVVMAFGFRPHSMEWLAKHSVELDSQGRIIAPERSDNAFQTSNPKIFAGGDIVRGSD
                     LVVTAIAEGRKAADGIMNYLEV"
     gene            6394..7497
                     /locus_tag="OPV72_000787"
     CDS             6394..7497
                     /locus_tag="OPV72_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1016 family protein"
                     /protein_id="HCR9913160.1"
                     /translation="MTNPTLAPQSDEYQQIHDGIIRLVDTARTETVRSINAIMTATYW
                     EIGRRIVEFEQGGEARAAYGTQLIERLSVDLSQRYKRGFSNRNLWQIRTFYLCFQHIE
                     IPQTLSAESSNLIPLAKTFPLPWSAYVRLLSVKDNDARTFYEKETLRNGWSVRQLDRQ
                     IATQFYERTLLSHDKSAMLQQPAPAEPNVLPEQAIRDPFILEYLNLKDEYSESDLEDA
                     LLSHLMDFMLELGDDFAFVGRQRRLRIDDSWFRVDLLFFHRRLRCLLLVDLKVGKFGY
                     ADAGQMNMYLNYAKEHWTMPGENPPVGLVLCAGKGAGEAHYALTGLPNTIMASEYKVQ
                     LPDEKLLTDELIRSQTMLETQLTRGGSLTTEKN"
     gene            7614..8867
                     /gene="codB"
                     /locus_tag="OPV72_000788"
     CDS             7614..8867
                     /gene="codB"
                     /locus_tag="OPV72_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HCR9913161.1"
                     /translation="MSQDNNYSQGPVPQAARKGVIPLTFVMLGLTFFSASMWTGGTLG
                     TGLTYHDFFLAVFFGNLLLGIYTAFLGYIGAKTGLSTHLLARYSFGVKGSWLPSLLLG
                     STQVGWFGVGVAMFAIPVSKATGIDANILIAVSGLLMTLTIFFGISALTILSIVAVPA
                     IVILGSYSVWLAVSGVGGLEHLKTIVPQTPLDFSSALALVVGSFVSAGTLTADFVRFG
                     RHAKSAVLIAMVAFFLGNSLMFIFGAAGAAAVGQADISDVMIAQGLLLPAIVVLGLNI
                     WTTNDNALYASGLGFANITGLSSRTLSVVNGIIGTVCALWLYNNFVGWLTFLSSAIPP
                     IGGVIIADYLVNRRRYADFNTVRFIPVNWIAILSVALGIAAGHYVPGIVPVNAVLGGV
                     FSYILLNPLFNRSLAKSPEVSHAEQ"
     gene            8854..10134
                     /locus_tag="OPV72_000789"
     CDS             8854..10134
                     /locus_tag="OPV72_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine deaminase"
                     /protein_id="HCR9913162.1"
                     /translation="MQNNNITIRQTRLQGHEGLWQITIENGRFSRIEPQEATSLPQGE
                     VLDAEGGLAIPPFVEPHIHLDTTQTAGEPSWNQSGTLFEGIERWAERKAMLTHEDVKA
                     RAMQTLKWQMANGIQYVRTHVDVSDPTLTALKAMLEVKQEVAPWVDLQIVAFPQEGIL
                     SYPNGEALLEEAVRLGADVIGAIPHFEFTREYGVESLHKTFALAQKYDRLIDVHCDEI
                     DDEQSRFVETVAALAHRDGMGARVTASHTTAMHSYNGAYASRLFRLLKMSGINFVANP
                     LVNIHLQGRFDTYPKRRGVTRVKEMLEAGINVCFGHDDVFDPWYPLGTANMLQVLHMG
                     LHVCQLMGYGQINDGLNLITTHSAKTLHLQDYGLSVGNAANLVILPAENGFDAVRRQT
                     PARYSIRHRRVIAETVPSQTTLHLTQPEAVTFKR"
     gene            complement(10216..10683)
                     /locus_tag="OPV72_000790"
     CDS             complement(10216..10683)
                     /locus_tag="OPV72_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HCR9913163.1"
                     /translation="MMMGEVQSLPSCGLHPRLLDALTLALAARPQEKAPGRYELQGDN
                     IFMNVMQLTTQMPAGKKAELHEQYIDIQLLLTGVERIAFGMSGAARQCEEMHVEEDYQ
                     LCSQIADEQTITLQAGMFAVFMPGEPHKPGCAVGEPDDIKKVVVKVRASLLAA"
     gene            complement(10680..11555)
                     /gene="nanK"
                     /locus_tag="OPV72_000791"
     CDS             complement(10680..11555)
                     /gene="nanK"
                     /locus_tag="OPV72_000791"
                     /EC_number="2.7.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine kinase"
                     /protein_id="HCR9913164.1"
                     /translation="MTTLAIDIGGTKLAAALIDNNLRISQRRELPTPASKTPDALREA
                     LKALVEPLRAEARQVAIASTGIIQEGMLLALNPHNLGGLLHFPLVQTLETIAGLPTLA
                     VNDAQAAAWAEYHALPDDIRDMVFITVSTGVGGGVVCDGKLLTGKGGLAGHLGHTLAD
                     PHGPVCGCGRVGCVEAIASGRGMAAAARDDLAGCDAKTLFIRAGEGHQQARHLVSQSA
                     QVIARMIADVKAITDCQCVVIGGSVGLAEGYLEQVRAFLMQEPEPYHVALSAARYRHD
                     AGLLGAALLAQGDTL"
     gene            complement(11552..12231)
                     /locus_tag="OPV72_000792"
                     /pseudo
     CDS             complement(11552..12231)
                     /locus_tag="OPV72_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462247.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
     gene            complement(12278..13768)
                     /gene="nanT"
                     /locus_tag="OPV72_000793"
     CDS             complement(12278..13768)
                     /gene="nanT"
                     /locus_tag="OPV72_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sialic acid transporter NanT"
                     /protein_id="HCR9913165.1"
                     /translation="MSTSTQNIPWYRHLNRAQWRAFSAAWLGYLLDGFDFVLIALVLT
                     EVQSEFGLTTVQAASLISAAFISRWFGGLLLGAMGDRYGRRLAMVSSIILFSVGTLAC
                     GFAPGYTTMFIARLVIGMGMAGEYGSSATYVIESWPKHLRNKASGFLISGFSVGAVVA
                     AQVYSLVVPVWGWRALFFIGILPIIFALWLRKNIPEAEDWKEKHAGKAPVRTMVDILY
                     RGEHRIINILMTFAAAAALWFCFAGNLQNAAIVAGLGLLCAVIFISFMVQSSGKRWPT
                     GVMLMLVVLFAFLYSWPIQALLPTYLKTELAYDPHTVANVLFFSGFGAAVGCCVGGFL
                     GDWLGTRKAYVCSLLASQILIIPVFAIGGTNVWVLGLLLFFQQMLGQGIAGILPKLIG
                     GYFDTDQRAAGLGFTYNVGALGGALAPILGALIAQRLDLGTALASLSFSLTFVVILLI
                     GLDMPSRVQRWLRPEALRTHDAIDDKPFSGAVPLGSGKGAFVKTKS"
     gene            complement(13884..14777)
                     /gene="nanA"
                     /locus_tag="OPV72_000794"
     CDS             complement(13884..14777)
                     /gene="nanA"
                     /locus_tag="OPV72_000794"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HCR9913166.1"
                     /translation="MAKALQGVMAALLTPFDHQQQLDSESLCRLVRFNIGQGIDGLYV
                     GGSTGEAFVQSLAEREQVLEIVAEEAKGKITLIAHVGTVSTAESQQLASAAKRYGFDA
                     VSAVTPFYYPFSFEEHCDHYRAIIDSADGLPMVVYNIPALSGVKLTLDQINTLVTLPG
                     VNALKQTSGDLFQMEQIRRAHPDLVLYNGYDEIFASGLLAGADGGIGSTYNIMGWRYQ
                     GIVQALREGDVAKAQRLQTECNKVIDLLIKTGVFRGLKTVLHYMDVVSVPLCRKPFAP
                     VDEKYLPALKALAQQLMEEKA"
     gene            complement(14912..15703)
                     /gene="nanR"
                     /locus_tag="OPV72_000795"
     CDS             complement(14912..15703)
                     /gene="nanR"
                     /locus_tag="OPV72_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NanR"
                     /protein_id="HCR9913167.1"
                     /translation="MDVMNAFDSQAEDSPTSLGRSLRRRPLARKKLSEMVEEELEQMI
                     RRHEFGEGEQLPSERELMAFFNVGRPSVREALAALKRKGLVQINNGERARVSRPSADT
                     IISELSGMAKDFLTHPGGIAHFEQLRLFFESSLVRYAAEHATDEQIALLTKALEINSQ
                     SLDDNALFIRSDVEFHRVLAEIPGNPIFMAIHVALLDWLIAARPSVPDRELHEHNNVS
                     YQQHIVIVDAIRQRDPDKADRALQTHLNSVSATWHALGKKSQKMR"
     gene            complement(15812..16312)
                     /gene="sspB"
                     /locus_tag="OPV72_000796"
     CDS             complement(15812..16312)
                     /gene="sspB"
                     /locus_tag="OPV72_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClpXP protease specificity-enhancing factor"
                     /protein_id="HCR9913168.1"
                     /translation="MDLSQLTPRRPYLLRAFYEWLLDNQLTPHLVVDVMLPGVHVPME
                     YARDGQIVLNIAPRAVGNLELSNDEVRFNARFGGVPRQVSVPLAAVLAIYARENGAGT
                     MFEPEAAYDEDVVSLNDDDNTAGAESETVMSVIDGDKPDHDDDSSPDDEPPPPRGGRP
                     ALRVVK"
     gene            complement(16318..16956)
                     /gene="sspA"
                     /locus_tag="OPV72_000797"
     CDS             complement(16318..16956)
                     /gene="sspA"
                     /locus_tag="OPV72_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stringent starvation protein A"
                     /protein_id="HCR9913169.1"
                     /translation="MAVAANKRSVMTLFSGPTDIYSHQVRIVLAEKGVSFEIEHVEKD
                     NPPQDLIDLNPNQSVPTLVDRELTLWESRIIMEYLDERFPHPPLMPVYPVARGESRLY
                     MHRIEKDWYTLMNVIVNGSASEVDSARKQLREELLAIAPVFGQKPYFLSDEFSLVDCY
                     LAPLLWRLPQLGIEFSGAGAKELKGYMTRVFERDSFLASLTEAEREMRLGRG"
     gene            17071..17244
                     /locus_tag="OPV72_000798"
     CDS             17071..17244
                     /locus_tag="OPV72_000798"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913170.1"
                     /translation="MNIPRYLGRKLDDSLPDFVTFVVSRFWNWGKRDNNPHFIVTDKC
                     IAHKKTRQSGFFR"
     gene            complement(17271..17663)
                     /gene="rpsI"
                     /locus_tag="OPV72_000799"
     CDS             complement(17271..17663)
                     /gene="rpsI"
                     /locus_tag="OPV72_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HCR9913171.1"
                     /translation="MAENQYYGTGRRKSSAARVFIKPGNGKIVINQRSLEQYFGRETA
                     RMVVRQPLELVDMVEKLDLYITVKGGGISGQAGAIRHGITRALMEYDESLRGELRKAG
                     FVTRDARQVERKKVGLRKARRRPQFSKR"
     gene            complement(17679..18107)
                     /gene="rplM"
                     /locus_tag="OPV72_000800"
     CDS             complement(17679..18107)
                     /gene="rplM"
                     /locus_tag="OPV72_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010847760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HCR9913172.1"
                     /translation="MKTFTAKPETVKRDWYVVDATGKTLGRLATELARRLRGKHKAEY
                     TPHVDTGDYIIVLNADKVAVTGNKRTDKVYYHHTGHIGGIKQATFEEMIARRPERVIE
                     IAVKGMLPKGPLGRAMFRKLKVYAGNEHNHAAQQPQVLDI"
     gene            complement(18408..19532)
                     /locus_tag="OPV72_000801"
     CDS             complement(18408..19532)
                     /locus_tag="OPV72_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AFG1 family ATPase"
                     /protein_id="HCR9913173.1"
                     /translation="MQSLSPTSRYLQALNEGTHQPDDVQKEAVDRLETLYQALTAKKS
                     SATPPGGLIARLGKLLGKNEPDAQIPVRGLYMWGGVGRGKTWLMDLFYHSLPGERKLR
                     LHFHRFMLRVHEELTALQGQIDPLDIIADRFKTETDVLCFDEFFVTDITDAMLLGGLM
                     KALFARGITLVATSNIPPEELYRNGLQRARFLPAIDAIKQHCDIMNVDAGVDYRLRTL
                     TQAHLWLTPLNDETRRQMDKLWLALAGAAREHAPTLEINHRPLSTLGVENQTLAASFA
                     TLCVEARSQHDYIALSRLFHTVLLFDVPVMTPLMENEARRFIALVDEFYERHVKLVVS
                     AAAPLYEIYQGERLKFEFQRCLSRLQEMQSAEYLKREHMP"
     gene            19725..20123
                     /locus_tag="OPV72_000802"
     CDS             19725..20123
                     /locus_tag="OPV72_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1043 family protein"
                     /protein_id="HCR9913174.1"
                     /translation="MTWEYALIGLVVGIIIGAVAMRFGNRKLRQQQALQYELEKNKAE
                     LEEYREELVSHFARSAELLDTMAHDYRQLYQYMAKSSSSLLPEMSAESNPFRNRLAES
                     EASNDQAPVQMPRDYSEGASGLLRSGAKRD"
     gene            20280..21647
                     /gene="degQ"
                     /locus_tag="OPV72_000803"
     CDS             20280..21647
                     /gene="degQ"
                     /locus_tag="OPV72_000803"
                     /EC_number="3.4.21.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine endoprotease DegQ"
                     /protein_id="HCR9913175.1"
                     /translation="MKKHTQLLSALALSVGLTLSAPFPALASIPGQVPGQATLPSLAP
                     MLEKVLPAVVSVKVEGTATQSQKVPEEFKKFFGEDLPDQPSQPFEGLGSGVIIDAAKG
                     YVLTNNHVINQAQKISIQLNDGREFDAKLIGGDDQSDIALLQIQNPSKLTQIAIADSD
                     KLRVGDFAVAVGNPFGLGQTATSGIISALGRSGLNLEGLENFIQTDASINRGNSGGAL
                     LNLNGELIGINTAILAPGGGSIGIGFAIPSNMAQTLAQQLIQFGEIKRGLLGIKGTEM
                     TADIAKAFKLNVQRGAFVSEVLPNSGSAKAGVKSGDVIISLNGKPLNSFAELRSRIAT
                     TEPGTKVKLGLLRDGKPLEVEVTLDSNTSSSASAEMIAPALQGATLSDGQLKDGTKGV
                     KVDSVEKSSPAAQAGLQKDDVIIGVNRDRISSIAEMRKVMAAKPSIIALQVVRGNENI
                     YLLLR"
     gene            21740..22810
                     /gene="degS"
                     /locus_tag="OPV72_000804"
     CDS             21740..22810
                     /gene="degS"
                     /locus_tag="OPV72_000804"
                     /EC_number="3.4.21.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane-stress sensor serine
                     endopeptidase DegS"
                     /protein_id="HCR9913176.1"
                     /translation="MFVKLLRSVAIGLIVGAILLAVMPSLRKINPIAVPQFDSTDETP
                     ASYNFAVRRAAPAVVNVYNRSMNSTAHNQLEIRTLGSGVIMDQRGYIITNKHVINDAD
                     QIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINTKRTPHIGDVVLAIGN
                     PYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINTL
                     SFDKSNDGETPEGLGFAIPFQLATKIMDKLIRDGRVIRGYIGIGGREIAPLHAQQGSG
                     MDPIQGIVVNEVTPNGPAALAGIQVNDLIISVNNKPAVSALETMDQVAEIRPGSVIPV
                     VVMRDDKQLTFQVTVQEYPASN"
     gene            complement(22844..23575)
                     /locus_tag="OPV72_000805"
     CDS             complement(22844..23575)
                     /locus_tag="OPV72_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase"
                     /protein_id="HCR9913177.1"
                     /translation="MIMLPQNEDTVMSEMVAFRQGTSMPSRETILRYVVETVNQITEL
                     EPALHLLPWSGVNSAIYEQRFAQCYDEGLCAAQTSAPNVPQGILPSTDWAQGIGLLCF
                     AAGYMSAGERPLTHNRLCDFVKQAAVGLSPIEGEAASGFSTVRSIALPVFRRLQRDGH
                     ASRVLLLQTLLHLVAWKSASQYARQQAQRLLWMGGILGEGSESGLLTLDKALREEAVG
                     EKSFPALLIFTSFLAHFPAGPVFID"
     gene            complement(23596..24897)
                     /locus_tag="OPV72_000806"
     CDS             complement(23596..24897)
                     /locus_tag="OPV72_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxalacetate decarboxylase subunit beta"
                     /protein_id="HCR9913178.1"
                     /translation="MESLNALLQGMGLMHLGAGQAIMLLVSLLLLWLAIAKKFEPLLL
                     LPIGFGGLLSNIPEAGMALTALESLLAHHDAGQLAVIAAKLNCAPDVHAIKEALALAL
                     PSVQNQMENLAVDMGYTPGVLALFYKVAIGSGVAPLVIFMGVGAMTDFGPLLANPRTL
                     LLGAAAQFGIFATVLGALTLNYFGLIAFTLPQAAAIGIIGGADGPTAIYLSGKLAPEL
                     LGAIAVAAYSYMALVPLIQPPIMRALTSEKERKIRMVQLRTVSKREKILFPVVLLLLV
                     ALLLPDAAPLLGMFCFGNLMRESGVVERLSDTVQNGLINIVTIFLGLSVGAKLVADKF
                     LQPQTLGILLLGVIAFGIGTAAGVLMAKLLNLCSKNKINPLIGSAGVSAVPMAARVSN
                     KVGLESNPQNFLLMHAMGPNVAGVIGSAIAAGVMLKYVLAM"
     gene            complement(24910..26685)
                     /gene="oadA"
                     /locus_tag="OPV72_000807"
     CDS             complement(24910..26685)
                     /gene="oadA"
                     /locus_tag="OPV72_000807"
                     /EC_number="7.2.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-extruding oxaloacetate decarboxylase
                     subunit alpha"
                     /protein_id="HCR9913179.1"
                     /translation="MTIAITDVVLRDAHQSLFATRLRLDDMLPIAAQLDDVGYGSLEC
                     WGGATFDACIRFLGEDPWLRLRELKKAMPKTPLQMLLRGQNLLGYRHYADDVVERFVE
                     RAVKNGMDVFRVFDAMNDPRNMKAALQAVRSHGAHAQGTLSYTTSPAHTLQTWLDLTE
                     QLLETGVDSIAIKDMSGILTPMAAFELVSEIKKRFEVRLHLHCHATTGMAEMALLKAI
                     EAGVDGVDTAISSMSATYGHPATEALVATLAGTEHDTGLDILKLENIAAYFREVRKKY
                     HAFEGQLKGYDSRILVAQVPGGMLTNLESQLKQQNAADRLDQVLAEIPRVREDLGFIP
                     LVTPTSQIVGTQAVLNVLTGERYKTIAKETAGILKGEYGHTPVPVNAALQARVLEGSA
                     PVTCRPADLLKPELAELEADVRRQAQEKGITLAGNAIDDVLTVALFPQIGLKFLENRH
                     NPAAFEPLPQAEAAQPVAKAEKPAASGIYTVEVEGKAFVVRVSDGGDISQLTTAVPAA
                     SSAPVQAAAPAGAGTPVTAPLAGNIWKVIATEGQSVAEGDVLLILEAMKMETEIRAAQ
                     AGTVRGIAVKSGDAVSVGDTLMTLA"
     gene            complement(26701..26940)
                     /locus_tag="OPV72_000808"
     CDS             complement(26701..26940)
                     /locus_tag="OPV72_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010836018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxaloacetate decarboxylase subunit gamma"
                     /protein_id="HCR9913180.1"
                     /translation="MNEAVLLGEGFTLMFLGMGFVLSFLFLLIFAIRGMSAVITRFFP
                     EPVAAPAPRAVPAVDDFTRLKPVIAAAIHHHRLNA"
     gene            complement(27099..28439)
                     /gene="citS"
                     /locus_tag="OPV72_000809"
     CDS             complement(27099..28439)
                     /gene="citS"
                     /locus_tag="OPV72_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate/sodium symporter CitS"
                     /protein_id="HCR9913181.1"
                     /translation="MTNMTQASATEKKGASDLLRFKIFGMPLPLYAFALITLLLSHFY
                     NAIPTDLVGGFALMFVMGAIFGEIGKRLPIFNKYIGGAPVMIFLVAAYFVYAGIFTQK
                     EIDAISNVMDKSNFLNLFIAVLITGAILSVNRKLLLKSLLGYIPTILAGIVGASLFGI
                     VIGLCFGIPVDRIMMLYVLPIMGGGNGAGAVPLSEIYHSVTGRSREEYYSTAIAILTI
                     ANIFAIIFAALLDMIGKKYTWLSGEGELVRKASFKTEDDEKAGQITHRETAVGMVLST
                     TCFLLAYVVAKKILPSIGGVSIHYFAWMVLIVAALNASGLCSPEIKAGAKRLSDFFSK
                     QLLWVLMVGVGVCYTDLQEIIDALTFANVVIAAIIVVGAVVGAAIGGWLIGFYPIESS
                     ITAGLCMANRGGSGDLEVLSACNRMNLISYAQISSRLGGGIVLVIASIVFSMMV"
     gene            28684..29727
                     /gene="citC"
                     /locus_tag="OPV72_000810"
     CDS             28684..29727
                     /gene="citC"
                     /locus_tag="OPV72_000810"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HCR9913182.1"
                     /translation="MQNRVNLIFKRIYLQKDVLRRESVAMFLEGVGLALEDDCEIAVC
                     AYWQGEIVGCGSLAGNVLKCIAVSPVLQGEGLSLKLLTELLTLAYELNRSELFLFTKP
                     QNRLLFSGAGFWPIAQAGELAVLMENSSERLARFCRQLALYRQPGKTIGAIVMNANPF
                     TLGHRYLVEQAAAACDWLHLFVVKEDASFFSYTDRWALIEQGIAGIDNVTLHSGSAYM
                     ISRATFPGYFLKEKGVVDDCHCQIDLQLFREHLAPALGITHRFVGSEPFCPLTCAYNQ
                     RMHDILHDPKRSGPVIEVVELARVEKNGTAISASRVRKLYSERNWPAISALVPAGTLA
                     YLQRHAARHTETI"
     gene            29757..30050
                     /gene="citD"
                     /locus_tag="OPV72_000811"
     CDS             29757..30050
                     /gene="citD"
                     /locus_tag="OPV72_000811"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HCR9913183.1"
                     /translation="MKIIKDALAGTLESSDVMIRIGPSSEPGIRLELESLVKQQFGAA
                     IEQVVRETLAKLGVERALVSVDDKGALECILRARVQAAALRAAEQTEIQWSAL"
     gene            30047..30916
                     /gene="citE"
                     /locus_tag="OPV72_000812"
     CDS             30047..30916
                     /gene="citE"
                     /locus_tag="OPV72_000812"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HCR9913184.1"
                     /translation="MRPRRSMLFIPGANAAMLSTSFVYGADAVMFDLEDAVALREKDT
                     ARLLVHHALQHPFYQDVEKVVRINPLNTPFGLADLEAVVRGGADIVRLPKTDSKNDVL
                     ELEAQVERIERECGREVGSTRLMAAIESAKGVVNAVDIATSSPRMVAIALAAFDYVMD
                     MGTSRGDGTELFYARCAVLHAARVAGIAAYDVVWSDINNEEGFLKEVQLAKGLGFNGK
                     SLVNPRQIELLHQAYSPTRKEVEHAHEVIAAAEEAESRGLGVVSLNGKMIDGPIIDHA
                     RKVVALSASGIRD"
     gene            30927..32447
                     /gene="citF"
                     /locus_tag="OPV72_000813"
     CDS             30927..32447
                     /gene="citF"
                     /locus_tag="OPV72_000813"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HCR9913185.1"
                     /translation="MKETVTMLNQQYVVPEGLQPYQGVTVNSPWLASETEKRRRKICD
                     SLEEAIRRSGLKNGMTISFHHAFRGGDKVVNMVMAKLAEMGFRDLTLASSSLIDAHWP
                     LIEHIKNGVVRQIYTSGLRGKLGEEISAGLMENPVQIHSHGGRVKLIQSGELNIDVAF
                     LGVPCCDEFGNANGFSGKSRCGSLGYAQVDAQYAKCVVLLTEEWVEFPNYPASIAQDQ
                     VDLIVQVDEVGDPEKITAGAIRLSSNPRELLIARQAANVIEHSGYFCDGFSLQTGTGG
                     ASLAVTRFLEDKMRRHNITASFGLGGITGTMVDLHEKGLIKALLDTQSFDGDAARSLA
                     QNPHHIEISTNQYANPGSKGAACERLNVVMLSALEIDVNFNVNVMTGSNGVLCGASGG
                     HSDTAAGADLTIITAPLVRGRIPCVVEKVLTTVTLGASVDVLVTDHGIAVNPARQDLL
                     DNLRAAGVALMTIEQLQQRAEQLTGKPQPIEFTDRVVAVVRYRDGSVIDVIRQVKG"
     gene            32447..32998
                     /gene="citX"
                     /locus_tag="OPV72_000814"
     CDS             32447..32998
                     /gene="citX"
                     /locus_tag="OPV72_000814"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HCR9913186.1"
                     /translation="MKGTDLLYQGQAVTLEEMLQARDKRAARQRQALNCYRLPLISLT
                     LVAPGAVKNSAVWRRVADYAIAEILALCEQKEWVNVWEMQVNERSGPEWMAAVCAPAM
                     ALKQHMSTLEMSHPLGRLWDIDIIDSDGKSLSRRELGHPARPCLICQQDAHLCARGKH
                     HTLDLLLDEIARRIECYERERCD"
     gene            32976..33884
                     /gene="citG"
                     /locus_tag="OPV72_000815"
     CDS             32976..33884
                     /gene="citG"
                     /locus_tag="OPV72_000815"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HCR9913187.1"
                     /translation="MNVSVVTERRTPAYSSLAAGELNGLVARALLTEARLTPKPGLVD
                     IRNSGAHRDMDLAAFERSTTAIAPWMEKFFIMGNNTAALAAENVLVMLRPLGMACEND
                     MLQATNGVNTHRGAIFAFGLLSAAIGRLLARGEPLEQNRICDQVARLSRNIVAHELSA
                     RKAGKLTKSETHFQCYGLSGARGEAESGFRTVRTQALPVFNRVVQEHDDTHLALLQTL
                     LHLMAWNDDTNLVSRGGLEGLYYVQQQAQKLLWQGGVLVEGGIEAMQFLDDELILRNL
                     SPGGSADLLAVTWFLSHFPAGSLYPE"
     gene            34064..34885
                     /gene="dapB"
                     /locus_tag="OPV72_000816"
     CDS             34064..34885
                     /gene="dapB"
                     /locus_tag="OPV72_000816"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HCR9913188.1"
                     /translation="MHEAQIRVAIAGAGGRMGRQLIQAAMAMEGVQLGAALEREGSSL
                     LGSDAGELAGAGKSGVIVQSSLEAVKDDFDVFIDFTRPEGTLTHLAFCRQHGKGMVIG
                     TTGFDDAGKQAIREASQEIAIVFAANFSVGVNVMLKLLEKAAKVMGDYSDIEIIEAHH
                     RHKVDAPSGTALAMGEAIAGALDKDLKDCAVYSREGYTGERVPGTIGFATVRAGDIVG
                     EHTAMFADIGERVEITHKASSRMTFANGALRSALWLKTKKNGLFDMRDVLGLDVL"
BASE COUNT         8045 a         9647 c         9733 g         7755 t
ORIGIN      
        1 aaaaaagtta tctgtgctac agcacacttt tgcataaatc agtttgccat ttgacctggg
       61 tgtggattcc cgataagttg gggatccgct ggaagctttc tggatgagcc gtctgctcat
      121 catatttatg cagtaattga gattccctct taaccgtatt taccaatgcg caaaggacac
      181 aaagagggcg aatgcgaggt aagcgtatga tgcgccagcc ccgtcgccat gctcttgctg
      241 tgcccgcgcg ccgtcggttg ggagagcgtc ccgtagagcc tggggaggtt cactgatatg
      301 ttgtacgata aatcccttga gaaggataac tgtggtttcg gcctgatcgc ccacatagaa
      361 ggcgaaccta gccacaaggt agtgcgtacc gccatacacg cgctggcccg gatgcagcac
      421 cgtggcgcga tccttgccga cggtaaaacc ggcgacggtt gcggcttgct gttacaaaaa
      481 cctgaccgtt tctttcgcat cgtggccgaa gagcgcggct ggcgcttagc caaaaactac
      541 gccgtcggga tgatcttttt gaataaagat cctgaactgg ccgccgcgtc acgccatatt
      601 gtcgaagaag aattacagca ggaaaccctg tcgattgtcg gctggcgcga tgtgccaacc
      661 aatgaaggcg tgctcggtga aatcgccctc tcctccctgc cgcgtattga gcagattttt
      721 gtcaacgctc cggcgggctg gcgtccgcgc gatatggagc gccgtctgtt tatcgcccgc
      781 cgacgcattg aaaaacgtct gcaggacgac aaagatttct acgtatgcag cctgtcgaac
      841 ctggtcaaca tttataaagg tctgtgtatg ccggcggatc tgccgcgctt ctacctggat
      901 cttgcggatc tgcgtctgga atcggccatc tgcctgttcc accagcgctt ttccactaac
      961 accgtgccgc gttggccgct ggcgcagccg ttccgctacc tggcgcataa cggcgagatt
     1021 aacaccatca ccggcaaccg ccagtgggcg cgcgcccgta cctataaatt ccagacgccg
     1081 ctgatcccgg atttacaatc cgctgcgccg tttgttaacg aaaccggttc ggattccagc
     1141 tcgctggaca acatgctgga actgctgctg gcaggcggga tggacattat ccgcgccatg
     1201 cgcctgttgg tgccgcccgc ctggcagaac aaccccgata tggaccagga tctgcgcgcc
     1261 ttctttgact ttaactccat gcatatggag ccgtgggacg gtccggcagg catcgtgatg
     1321 tccgacgggc gcttcgccgc ctgtaacctt gaccgtaacg gcctgcgccc ggcacgctat
     1381 gtcattacca aagataagct gatcacctgc gcctccgaag tcggtatctg ggactatcag
     1441 ccggatgaag tggtcgagaa aggccgcgtc ggcccaggcg agctgatggt gatcgacacc
     1501 cgcggcggac gtattctgca ttccgcggaa accgatgacg atctgaaaag ccgccatccg
     1561 tataaagcgt ggatggaaaa gaatgttcgc cgtctggtgc cgtttgaaga gttgccagat
     1621 gaagaagtcg gtagccgcga actggacgat gacctgctcg ccagctatca gaaacagttt
     1681 aactacagcg ccgaagagct ggactccgtt atccgcgtgt tgggcgaaaa cggccaggaa
     1741 gccgtcggtt caatgggcga cgataccccc tttgccgtgc tctccagcca gccgcgtatt
     1801 atttacgact acttccgcca gcagttcgcg caggttacta acccgcctat cgacccgctg
     1861 cgggaagcgc acgtcatgtc gctcgccacc agcatcggtc gcgaaatgaa cgtcttctgc
     1921 gaagcggaag gtcaggccca tcgcctgagt tttaaatcgc caattctgct gtactccgat
     1981 ttcaaacagc tcaccaccat gagcgagcat cactaccgcg ccgactggct tgacattacc
     2041 tttgatgtca ccgaaaccac actggacgcg acggttaagg cgctgtgcga taaagcggaa
     2101 cagatggtgc gcaacggcac cgtgctgctg gtcctctcgg atcgcaatat cggtaagaat
     2161 cgcctgccgg tccccgcgcc gatggcggtg ggcgcggtgc agactcgtct ggtcgatcaa
     2221 agcctgcgct gcgacgccaa catcatcgta gaaaccggaa gcgcccgcga tccgcatcac
     2281 tttgcggtac tgctcggctt tggcgcaacg gccatctatc cgtacctggc ctacgaaacg
     2341 ctggggcgtc tgattgatac ccaggccatc gctaaaaact accgtaccgt gatgcagaac
     2401 taccgtaacg gcatcaacaa ggggctgtac aagattatgt ccaaaatggg catttcgacc
     2461 attgcctctt accgctgctc caaactgttt gaagcggtcg ggctgcacga tgatgtggta
     2521 aacctgtgct tccagggcgt ggtcagccgt atcggcggcg cgagctttga tgacttccag
     2581 caggatctgc tgaatctctc caaacgcgcc tggctggcgc gcaaacccat tagcccgggc
     2641 ggcctgctga agtacgtcca cggcggcgaa tatcacgcct ataacccgga tgtcgtgcgt
     2701 accctgcaac aggcggtaca gagcggcgag tacagcgatt atcaggaata cgccaaactg
     2761 gtcaatgagc gtccggctgc aacgctgcgc gatctgctgg cgatacatcc agacggcgag
     2821 gcggtgacta tcgacgaggt tgagcccgcc agtgagctgt ttaaacgctt tgataccgca
     2881 gccatgtcta tcggcgcatt aagtccggaa gcgcacgaag cgctggcgga agcgatgaac
     2941 agcctcggcg gcaactccaa ctccggcgaa ggcggcgaag acccggcgcg ctacggcacc
     3001 aataaagtgt cgcgtatcaa gcaggtggct tccggccgtt ttggcgtgac gccagcgtac
     3061 ctggtcaatg ccgatgtgat tcagattaaa gtcgcgcagg gcgcgaaacc gggcgaaggc
     3121 ggtcagttgc cgggggataa agtcactccg tatatcgcta aactgcgcta ttcagtgccg
     3181 ggcgtgacgc tgatctcccc gccgccgcac cacgatattt actctatcga ggacttagcg
     3241 cagctcattt tcgacctcaa acaggtcaac ccgaaggcga tgatctccgt gaagctggtg
     3301 tccgaaccgg gcgtcggcac catcgcgacc ggcgtggcga aagcctatgc agacctcatc
     3361 accatcgctg gctacgacgg cggtaccggc gcaagcccgc tctcttcggt gaaatacgct
     3421 ggctgcccgt gggaactagg acttgttgaa acccagcagg cgctggtcgc caacggtctg
     3481 cgtcacaaga ttcgtctgca ggtggacggc ggtctgaaaa ccggcgtcga tatcatcaaa
     3541 gcggcgattc tcggtgcaga aagtttcggc ttcggcaccg gcccgatggt ggcgctgggc
     3601 tgtaaatacc tgcgcatttg ccatctgaac aactgcgcaa ccggcgtggc gacgcaggat
     3661 gaaaaactgc gtaagaacca ctatcacggc ctgccgttca aagtgaccaa ctactttgaa
     3721 tttatcgccc gcgaagtgcg cgagctgatg gcttcgcttg gcgtgacccg cctggtggat
     3781 ttgattggcc gcaccgacct gctgaaagag ctggagggct tcaccgctaa acagcagaag
     3841 ctggcgctgt ctcgtctact ggaaaccgct gaacctcatc cgggtaaagc gctgtactgc
     3901 accgagaata acccgccgtt tgataacggt gtgctgaatg cgcaactgtt gcagcaggcg
     3961 aagccgtttg tcgatgcgcg ccagagcaaa accttctggt tcgacatccg caacaccgat
     4021 cgttccgtgg gtgcgtcgct ttccggttac atcgcacaga cccacggcga tcaggggctg
     4081 gcttccgatc cgattaaagc gcacttcagc ggtaccgcag gccagagctt tggcgtgtgg
     4141 aacgcgggcg gcgtggagtt atatctgact ggcgatgcca acgactatgt cggtaaaggt
     4201 atggcaggcg gtttgatcgc catcagacca ccggtaggtt ccgccttcct cagccataaa
     4261 gccagcatca tcggcaacac ctgcctgtat ggagcgaccg gtggccgtct gtacgcggcg
     4321 gggcgcgcgg gcgaacgttt cggcgtgcgt aactccgggg cgattaccgt agtagagggc
     4381 atcggcgaca acggctgtga atacatgacc ggcggcatcg tctgcgtgct gggtaaaacc
     4441 ggcgttaact tcggcgcggg gatgaccggc ggcttcgcct atgtgctgga cgaagatggc
     4501 gaattccgta aacgcgtgaa cccggaactg gtagaagtac tggacgttga ttcgctggct
     4561 atccacgaag agcatctgcg cggcctgatc accgagcacg tgcaacatac tggttcgcaa
     4621 cgcggcgaag agatcctgtc caggtggtca agcttctcaa cccaattcgc gttagttaag
     4681 cccaagtcca gcgatgtcaa agccctgttg ggccaccgta gtcgtagtgc ggcagaattg
     4741 cgcgtgcagg cgcagtaagg aattgaaatg agccagaatg tttatcaatt tatcgacctg
     4801 cagcgcgttg atccgccgaa gaaaccgctg aagctccgta agatcgagtt tgttgaaatc
     4861 tacgaaccgt tttctgaagg tcaggcgaaa gcccaggcgg atcgctgttt gtcctgcggg
     4921 aacccctact gcgagtggaa atgtccggta cataactaca tcccgaactg gctgaaactg
     4981 gctaacgaag ggcgtatttt tgaggcggct gagctatcgc accagaccaa caccctgccg
     5041 gaagtgtgtg gccgcgtctg cccgcaggac cgcctgtgcg aaggctcctg tacgctgcac
     5101 gatgagttcg gcgcagtgac catcggtaac attgagcgct atatcaacga taaagcgttc
     5161 gaaatgggct ggcgcccgga tatgaccggc gtgcgccaga cggacaaacg ggtagcgatt
     5221 atcggcgctg gtccggcagg gctggcgtgc gccgacgtgc tgacccgcaa cggcgtgaag
     5281 gcggtggtct ttgatcgcca tccggaaatc ggtggtctgc tgaccttcgg tattccagct
     5341 ttcaaactgg aaaaagaggt gatgacccgt cgtcgcgaga tcttcaccgg catgggtatt
     5401 gagttcaaac ttaataccga agtgggtcgt gatgtacagc ttgaagatct gctgaaagat
     5461 tacgatgcgg tattccttgg cgtcggcacc tatcagtcga tgcgcggcgg gctggaaaat
     5521 gaagatgcgg acggggtttt cgacgctcta ccgttcctga tcgccaatac gaagcagatc
     5581 atggggtttg gcgaaaccag cgacgaacca tatgtcagca tggaaggcaa acgcgtggtg
     5641 gtgctgggcg gcggcgatac cgcaatggac tgcgtacgca cttccatacg ccagggcgca
     5701 acgcacgtaa cctgtgctta tcgtcgtgat gaagagaaca tgccgggttc cagacgcgaa
     5761 gtgaaaaacg cgcgcgagga aggtgtcgag tttcagttta acgttcaacc gctgggcatt
     5821 gaagtcaatg ccaacggcaa agtgagcggc gtaaaaatgg tgcgcactga aatgggcgaa
     5881 ccggatgcca aaggccgtcg gcgggcggag atcgtcgccg gttccgagca tgtggttccg
     5941 gctgatgcgg tggtgatggc gtttggtttt cgtccacaca gcatggaatg gctggcgaaa
     6001 cacagcgtgg aactggactc gcagggacga attatcgcgc cggaacgcag cgataatgct
     6061 ttccagacca gcaacccgaa aatcttcgcc ggtggcgaca tcgtgcgcgg ttccgatctg
     6121 gtggtgacgg cgattgccga aggccgtaaa gcggctgacg ggattatgaa ctacctcgaa
     6181 gtgtaaccct ttcggctccc cggttgatgc cttgtgctga tggctgggga gccgatattc
     6241 ctctcctcaa tatctctcct gccgattctg gaaacccgct cgtaaatcga gatgtaatgc
     6301 catgtaaaat ccgttcatgg attgattcgt ttacgcctga agcgtattga tagcgttcta
     6361 atttcacaat gaaactatca cgtaagggat gacatgacga atccaacttt agcgccacag
     6421 tctgatgaat atcagcaaat tcatgacggt attattcgtc tggtcgatac ggcacgtacc
     6481 gagaccgtgc gcagcatcaa tgccattatg actgccacct actgggaaat tggccgacgt
     6541 attgtcgaat ttgaacaggg aggagaagcg cgagcggcct atggcaccca gcttatcgaa
     6601 cgattatcgg tagatttaag tcagcgctat aagcgcggtt tttccaacag aaacctatgg
     6661 caaattcgta cattttatct ttgttttcaa cacattgaaa ttccgcagac actgtctgcg
     6721 gaatcttcaa atctcatacc gctcgccaaa acattccctc ttccctggtc agcttatgtg
     6781 cgtctgctgt cggtgaaaga taacgatgcc cgcacttttt acgagaaaga gacgctacgt
     6841 aacggctggt ccgtacggca actcgatcgg caaatcgcca ctcaatttta cgaacgaacg
     6901 ctactgtccc acgacaaatc cgccatgttg cagcagcctg cacccgccga gccaaacgtt
     6961 ttgccggagc aagccatacg cgacccgttc attctggaat atcttaacct gaaggacgag
     7021 tattccgaat cagatctcga agacgcgctg ctcagccacc tgatggactt tatgctggag
     7081 ctcggtgacg attttgcttt tgttggccgc caacgccgac tacgcataga cgatagctgg
     7141 ttccgcgtcg atctgctgtt cttccatcgt cgcttgcgct gcctgttgct cgttgacctg
     7201 aaggtaggca aattcggtta tgcggatgcc gggcagatga atatgtacct gaactatgcc
     7261 aaagagcact ggacaatgcc cggagaaaac ccgccagtcg gcctggtttt gtgcgcaggg
     7321 aaaggcgcgg gggaagcgca ttacgcgctg actggcctgc caaacaccat catggcgagc
     7381 gagtacaaag tgcagttgcc cgacgaaaaa ttactcacag acgaacttat tcgttcgcaa
     7441 accatgctgg aaactcaact cacacgcggt ggttcactga caacggagaa aaactagcga
     7501 accattaatg ccatgaataa ttatcaaaaa aaatatcaca cgaaaacgtt tgctttattc
     7561 tgagaactgt atattatgcg gcggattttt tgggcaaaat tcatggaggc gttgtgtcgc
     7621 aggacaacaa ttatagccag gggccagttc cccaggcggc gcggaagggc gtgattccac
     7681 tgacgtttgt catgttgggt ttaacgtttt tttccgccag tatgtggacc ggagggacac
     7741 tcggcaccgg tcttacctat catgatttct tcctcgcagt tttcttcggt aatctcctcc
     7801 tcggtatcta cactgcattt cttggctaca tcggcgcaaa aaccggactc tccacccacc
     7861 tccttgcacg ttactccttt ggcgttaaag gctcatggct tccctcgctg ctgttaggca
     7921 gtactcaagt gggctggttt ggcgttggcg tagcgatgtt cgctattccg gtcagtaaag
     7981 cgacgggcat tgatgccaat atcctgattg ccgtttcggg tctgctgatg accctgacca
     8041 tttttttcgg catctcggcg ttgaccattt tgtctatcgt tgccgtaccc gcgatcgtta
     8101 ttctgggcag ctactccgtc tggctggcgg tcagcggcgt gggtgggctg gagcatttaa
     8161 aaacgatagt gccgcagacg ccgctggatt tttccagcgc gctggcgctg gtggtgggct
     8221 cgtttgtcag cgccggtaca ttgaccgccg acttcgtccg cttcggacgt catgccaaaa
     8281 gcgccgtact gattgcgatg gtcgcttttt tcctcggtaa ctcgctgatg tttatcttcg
     8341 gcgcggcagg cgctgccgcc gtcggtcagg cggatatctc tgacgtgatg atagcgcagg
     8401 ggctgctgct gcccgcgatt gtggtgcttg gcctgaatat ctggaccacc aacgataacg
     8461 cgctgtacgc atcgggtctg ggcttcgcca atattaccgg tctttccagc cgcacgctgt
     8521 cggtggtgaa cgggattatc ggtaccgtgt gcgcgctgtg gctttacaat aattttgtcg
     8581 gctggctgac gttcctgtca tctgccatcc caccgattgg tggagtgatt attgccgact
     8641 atctggtgaa ccgccgccgc tatgccgact tcaacaccgt gcgctttatt cccgttaact
     8701 ggattgctat tctttccgtc gcgctgggca tcgccgccgg acattatgtt cctggtattg
     8761 tgcccgtcaa cgccgtactc ggcggcgtct tcagctatat cctgctgaat ccacttttca
     8821 accgcagcct tgctaaatca ccagaggtca gccatgcaga acaataacat cactattcgt
     8881 cagacgcgtc tgcagggaca cgaaggatta tggcagatta cgattgaaaa cgggcgcttt
     8941 agccggattg agcctcagga agccacatcg ttaccgcagg gcgaagtgct tgatgccgaa
     9001 ggcggtctgg ctattccacc gtttgttgag ccacatatcc acctggatac cacgcaaacg
     9061 gcgggtgaac cgagctggaa ccagtccggc acactgtttg aagggattga gcgctgggca
     9121 gaacgtaaag caatgctcac gcatgaagat gtgaaagcgc gcgcgatgca gaccctgaaa
     9181 tggcagatgg ctaacggcat ccagtacgtt cgtactcacg ttgacgtttc agatcctacg
     9241 ctcaccgcgc tgaaagccat gctggaagtg aagcaagagg ttgcgccgtg ggtagaccta
     9301 caaatcgtcg cctttccgca agaaggtatt ctgtcttatc ccaacggtga agcgctgtta
     9361 gaggaagccg tgcgtttggg cgctgacgtt attggcgcca ttccgcactt tgagttcacg
     9421 cgggaatatg gcgttgaatc gctgcacaaa accttcgccc tggcgcaaaa atacgatcgc
     9481 ttgatcgatg tgcactgcga cgaaattgat gacgagcagt ctcgctttgt cgaaacggtc
     9541 gcggcgctgg cgcatcgtga tggcatgggg gcgcgcgtga ccgccagcca caccacggct
     9601 atgcactcgt acaacggcgc gtatgcgtca cgcctgttcc gtctgttgaa aatgtcgggg
     9661 attaacttcg tcgccaaccc gctggtaaat attcatctgc aagggcggtt tgacacttac
     9721 ccgaaacgtc gtggcgtcac gcgagtgaaa gagatgctgg aagcggggat caacgtctgc
     9781 tttggccatg atgacgtctt cgacccgtgg tatccattag gcaccgccaa tatgctgcag
     9841 gtgctgcata tggggttaca cgtttgccag ttgatggggt atgggcaaat caacgacggg
     9901 ttaaatctga tcactaccca cagcgcaaaa actttgcacc tgcaggacta cggtctgagc
     9961 gtcggcaatg ccgcgaatct ggttatctta cccgctgaga atggattcga tgcggtacgt
    10021 cgccagacgc ctgcccgtta ctcaattcgc cacaggcggg tgattgccga gacggtgccg
    10081 agccagacga cgctgcacct gacccagccg gaagccgtga cgtttaagcg ttaacccgtc
    10141 atacccgcgc tctccggcac attcaccacg cagcccgtaa ggggctgcgt tcggaagact
    10201 gctccggcaa gagattcagg ccgccagcaa actggcgcgt actttcacta ccactttctt
    10261 gatgtcatcc ggttcaccca ctgcacatcc cggtttatgc ggttctcccg gcataaacac
    10321 agcaaacatc cccgcttgca gcgtaatagt ctgctcgtcg gcaatttgac tacaaagctg
    10381 gtaatcctct tcaacgtgca tctcctcgca ctggcgagcg gcaccggaca tcccaaacgc
    10441 aatacgctcg acgccggtta gtagtagctg aatatcaatg tattgttcat gcaattccgc
    10501 tttcttcccg gcaggcattt gcgtcgttaa ctgcattaca ttcataaaga tattgtcgcc
    10561 ctgcaattca tagcgccccg gtgctttctc ctgcggcctt gccgccagcg cgagagtcaa
    10621 ggcatccagc agtcgcggat gcaacccgca agaaggcaac gactgtactt cccccatcat
    10681 cataatgtgt ctccttgagc taacaaagca gcgcctaata atcctgcgtc atgccgatag
    10741 cgagcggcgc tcagcgccac gtgataaggc tcaggctctt gcatcaaaaa cgcgcgaacc
    10801 tgctccaggt atccctcagc taaccctacg ctgccgccaa tgaccacaca ctggcagtcg
    10861 gtaatcgctt tcacatcggc gatcattcgc gctattacct gcgcggattg gcttaccaga
    10921 tgtcgcgcct gctgatgacc ttcgccagcg cgaataaata gggttttggc gtcgcatccc
    10981 gccagatcgt cccgcgccgc cgcggccatc cctcgtccgg aggcgatggc ctctacacaa
    11041 ccaacgcgtc cacagccgca tacgggcccg tgtgggtccg ccagggtgtg tcccaggtgc
    11101 ccggccagac cgccttttcc ggtaaggagc ttgccgtcgc agacaacgcc gccgccaacg
    11161 ccggttgaaa cggtgataaa taccatatcg cggatatcat cagggagcgc gtgatactcc
    11221 gcccaggccg ccgcctgcgc gtcgttcacc gccagcgtcg gcaggccagc gatcgtttcc
    11281 agtgtttgta ctaacggaaa gtgtagcaag ccgcccagat tatgggggtt tagcgccagc
    11341 agcatccctt cctgaatgat cccggtagaa gctatcgcta cctgacgcgc ctctgcccgt
    11401 agtggttcaa ccagcgcctt taatgcttca cgtaacgcat ccggcgtttt gctcgcgggg
    11461 gtcggtagct cgcgacgctg gctaatgcgc aagttgttgt cgatgagcgc ggcggcaagt
    11521 ttagtaccgc caatatcgat tgctaacgta gtcatgacgc cgcctttttt aatgcgtcgt
    11581 tataccatcc acagatatgt tccagacggg taatggcgga ccccaccgtc accgcccatg
    11641 cgccatagcg gatcgcctcc gccgccagtg ctggcgagtt atagcgccct tcggctatta
    11701 cccggcatcc ggcgtcatgc aacgctttga ctaagggcag atcgggttcc tccggcgtat
    11761 cgggggtggt gtagccggac attgtcgtgc cgataatgtc cgcgcccaac cgttggcagg
    11821 cgagaccatc gtccacggat gagcagtcgg ccatcgccag tagatggtgg tgatgaatgc
    11881 gcgccaacaa cgcctcaacg gctaccggcc gttgccgagc ggttccatca acggcgataa
    11941 tagctgcgcc agcgcatcta catcgtcgag aaaaggggta atgcgcactg gagagtcgtc
    12001 cagatcgcgt ttgataatgc cgataatggg taccgaaacg agcgaacggg ccacgcgcag
    12061 gttgtctatg ccttcaatac gcaccgcaac cgcgcccgcc tgttccgccg ccaacgccat
    12121 tgccgctaca atctccggct tatccagcgg actgcccgga acgggctggc aggagacaat
    12181 caggccgcca gaagcggcaa tatttttatc cagttgttca agtaacgaca tactactccc
    12241 ttacaaatat tgcccggttg aaaaccgggc aagcggatta acttttcgtt tttacaaagg
    12301 cacctttacc actgccaagc ggtacggctc cgctgaacgg tttgtcgtcg atagcatcat
    12361 gggtgcgtaa cgcttccgga cgtagccaac gctgtacgcg agacggcata tcaagcccaa
    12421 taagcaggat cacgacaaac gtcaggctga aagagagcga tgccagcgca gtgcccagat
    12481 ccagacgttg agcgatcagc gctcccagga tcggtgccag cgcgccgccg agcgcgccga
    12541 cgttataagt aaagcccagc cccgccgcgc gctgatcggt atcgaagtaa ccgccgatca
    12601 gtttcggcag aatcccggca atcccctgcc ccaacatctg ttggaaaaac agtagcagac
    12661 ccagaaccca gacgtttgtg ccgccaatcg caaagaccgg aataatgagg atttgcgagg
    12721 ccagcaggct acagacatat gctttacgcg ttcccagcca gtcgccaaga aaaccgccta
    12781 cgcaacaacc aaccgccgcg ccaaatccgc taaagaacag gacattcgcc accgtatgcg
    12841 gatcgtaggc cagctcggtt ttcagataag taggtaatag cgcctgaatc ggccaagaat
    12901 agaggaaagc aaacagtacc accagcatca gcatgacgcc agtgggccag cgtttaccgc
    12961 tgctctgcac cataaagctg ataaagataa ccgcgcacag tagtcccagc cccgccacaa
    13021 tcgcagcatt ttgtaggtta ccggcaaaac agaaccacag cgcagcggcg gcggcgaagg
    13081 tcattaaaat gttgatgata cgatgttcgc cccgataaag aatgtcgacc atcgtgcgta
    13141 ccggcgcttt acccgcgtgt ttttctttcc agtcttccgc ttccggaatg tttttccgca
    13201 gccagagggc gaagataatt ggcaaaatgc caatgaaaaa cagcgcgcgc cagccccaga
    13261 caggcaccac caggctgtac acctgcgcgg caacgaccgc gccgacggag aagccggaaa
    13321 tcagaaaacc actggcttta ttgcgtaaat gttttggcca gctttcaatc acataggtcg
    13381 cgctggaacc atattcgccc gccatgccca taccaatcac cagtcgggcg atgaacatgg
    13441 tggtgtaacc gggcgcaaac ccgcaggcca gggttcccac cgaaaacaga atgatgctgc
    13501 tgaccatcgc cagacgacgc ccatagcgat cgcccatcgc gcccagtaat aacccgccga
    13561 accagcgaga gataaaagcc gcagaaatca ggcttgccgc ctgtaccgtc gtcagcccaa
    13621 attcgctttg tacctcagtc agtacaagag caattaacac aaaatcaaaa ccatcaagca
    13681 gatatcccaa ccaggcagcg gaaaatgccc gccattgcgc ccggttgaga tggcgatacc
    13741 acgggatgtt ctgggtagaa gtactcattt tactctcccg acgatttttg ttgtcgttat
    13801 gccgaatggc ggctccgcct tatccggcct actgttcgca ctgttgtagg ccgggcaagc
    13861 gtagcgcccc cggcattatg ctgttacgcc ttttcttcca tcagttgttg agccagcgcc
    13921 ttgagcgccg gcagatattt ttcatcaaca ggcgcaaacg gtttacgaca tagcggcacc
    13981 gataccacgt ccatataatg caggaccgtt ttcaggccgc ggaatacgcc ggttttaatc
    14041 agtaaatcaa taaccttatt gcactcggtt tgcagacgct gcgctttcgc cacatcgccc
    14101 tcacgcaatg cctgaacaat cccctgataa cgccaaccca taatgttgta tgtgctgccg
    14161 ataccgccgt ccgcgcccgc cagcagaccg gaagcgaaga tttcgtcata accgttgtac
    14221 agcaccagat ccggatgcgc gcggcggatc tgctccatct ggaagagatc gccggaggtt
    14281 tgcttcagcg cgttcacgcc cggtaatgtc accagcgtat tgatctgatc gagggtaagt
    14341 tttacgccgc ttaacgccgg aatgttgtat accaccatcg gcaatccatc tgcggaatca
    14401 atgattgccc gataatggtc acagtgctct tcaaaactga aagggtaata aaaaggcgtc
    14461 accgcagaga ccgcatcaaa accgtaacgc tttgcggcgc tggcaagctg ctggctttct
    14521 gcggtgctta ctgtcccgac atgggcgatc aacgtgattt ttcccttcgc ctcttcggcg
    14581 acaatctcca gtacctgctc tctttcagca aggctctgta cgaatgcttc cccggtggaa
    14641 ccgccaacgt acagcccgtc gataccctgc ccgatgttaa aacgcaccag acggcacagg
    14701 ctttcgctat ccagttgctg ctgatgatca aatggggtca acaacgccgc cattacgcct
    14761 tgcaatgctt ttgccatacc tacctctacg gatgatgaat atattaacta cctaccttta
    14821 tacctgttat accagatcaa ataagcagca aataatacag aacgcttata gtgcgatctg
    14881 cttcactaaa ccgggatcgg aggtgcgatc gctaccgcat tttttgactt tttttaccga
    14941 gcgcgtgcca ggtagcggaa acgctattga ggtgggtttg cagagcgcga tccgctttat
    15001 cgggatctcg ctggcgaatg gcatcaacaa tcacaatatg ctgttgataa ctcacgttat
    15061 tatgttcatg cagctcacga tcgggaacgc ttgggcgagc agcgattagc cagtccagca
    15121 gagcaacatg aatagccata aagatcggat tgccgggaat ttcagccagc acccggtgaa
    15181 actcgacatc cgaacgaata aacagcgcgt tgtcatccag cgactggcta ttaatttcca
    15241 gcgctttcgt taacaacgcg atctgctcgt cggtggcatg ttccgccgca tagcgtacca
    15301 ggctggattc aaagaaaagc cgtagctgtt caaagtgagc gatgccgcca ggatgagtaa
    15361 gaaaatcttt cgccataccc gacagttcgc tgatgatggt atcagcagag gggcgcgaga
    15421 cgcgggcgcg ttcgccgtta ttgatttgca ccagaccttt acgcttcagc gcagctaacg
    15481 cttcacgcac ggagggacgt cccacattga agaaggccat taattcacgt tcagacggta
    15541 gctgttctcc ctcgccaaac tcatgacggc ggatcatctg ctccagctct tcctcaacca
    15601 tttcagacag ttttttacgc gccagcgggc ggcggcgcaa actacgcccg agggatgtcg
    15661 gtgaatcttc tgcttgcgaa tcaaatgcgt tcataacgtc cattcatgag tggtcggtgg
    15721 caaataatag caagcttatc gtaacacagc ttcaaaagca gggtgaaccc gcgaggagac
    15781 caaacaaaac aggcccttca gggcctgttg attattttac tacgcgcagc gccggacgtc
    15841 cgccacgcgg cggaggcggc tcgtcatcag gactactgtc gtcatcgtgg tcgggcttat
    15901 cgccatcaat gacggacatc acggtctcgc tttccgcgcc tgcggtattg tcatcatcat
    15961 ttaagctgac aacgtcttca tcataggcgg cttcaggctc aaacatggtg cctgcgccgt
    16021 tttcacgggc gtaaatcgcc agcaccgcag ccaaaggcac agaaacctga cggggaacgc
    16081 cgccgaagcg cgcattaaaa cgcacttcat cattagacag ctccagatta cctaccgccc
    16141 gcggcgcaat attgaggacg atttgcccat cgcgcgcata ttccataggg acatgcacgc
    16201 caggcagcat cacatccacc accagatgcg gggtcaactg gttatccagc aaccactcgt
    16261 agaaagcacg caacagatag ggacgacgcg gcgtcaactg tgacaaatcc atacaggtta
    16321 accccgaccg aggcgcattt cacgttcagc ttcggttaaa gaagccagga aagaatcacg
    16381 ttcaaagacg cgggtcatat agcctttcag ctctttcgcc cctgcgccgc tgaattcgat
    16441 acccaactgc ggtaaacgcc acaggagagg cgccaggtag caatcaacca ggctgaattc
    16501 gtcgctcagg aaatacggtt tctgaccaaa taccggcgca atcgccagca gctcttcacg
    16561 cagttgttta cgcgcagagt cgacctcgga agcagacccg tttacgatga cgttcatcag
    16621 cgtataccag tctttttcaa tacggtgcat gtacagacgg ctttcaccgc gcgcgaccgg
    16681 ataaaccggc atcagcggcg gatgggggaa acgctcatcc agatattcca taatgatgcg
    16741 agattcccac agggtcagct cacgatccac cagtgtcgga acgctttgat tcgggttgag
    16801 gtcaatcaga tcctgaggtg gattgtcctt ttccacatgt tcgatctcaa aactaacacc
    16861 cttttcagcc aacacaatgc ggacctgatg gctatagatg tcagtaggac cagaaaacag
    16921 cgtcattacc gaacgtttgt tggcagcgac agccatgaaa acctccaggt atattcagaa
    16981 tttttactgc taccagccac aatgtgacca gccagatgtt atgtcaccca gggcgaaaaa
    17041 agccatcatt gctcagaaac gagacaaaaa atgaacattc cccgctattt gggcagaaaa
    17101 ttggatgata gtttaccaga ttttgtgacc tttgtggtga gtcgattctg gaattgggga
    17161 aaaagagaca acaatccgca tttcattgtg acagataaat gcattgccca taaaaaaacc
    17221 cgccaaagcg ggttttttcg ctaacagttg tctgccgaag cagaaaacaa ttaacgtttg
    17281 gagaactgcg gacgacgacg tgctttacgc aggccgactt tcttacgttc aacctgacga
    17341 gcgtcacgag taacgaagcc agctttacgc agttcgccac gcagggactc gtcgtactcc
    17401 atcagagcgc gggtgatacc gtgacggatc gcaccagcct gaccagagat accaccacct
    17461 ttaacagtga tgtacagatc cagtttctca accatgtcga ccagttccag cggctgacga
    17521 actaccatgc gggcagtttc acgaccgaag tactgttcca gagaacgttg gttgataacg
    17581 attttaccgt tgcccggctt gatgaaaacg cgagctgcgg aacttttgcg gcgaccagtg
    17641 ccgtagtatt gattttcagc cattgcctat aatcccgatt agatgtcaag aacttgcggt
    17701 tgctgtgccg cgtggttgtg ctcgttgccc gcgtaaactt tcagtttacg gaacatagca
    17761 cgacccagcg ggccttttgg cagcatgcct ttaaccgcga tttcaatcac acgctcagga
    17821 cggcgggcaa tcatctcttc aaaggtcgct tgtttgatac caccgatgtg gccggtgtgg
    17881 tgatagtaca ctttgtcagt acgcttgttg ccggttacag caactttgtc agcgttcaga
    17941 acgatgatgt aatcaccggt atctacgtgc ggagtgtatt ccgctttgtg cttaccgcgc
    18001 aggcgacgag ccagttcagt agccagacgg cccagagttt taccggtcgc gtcaacaaca
    18061 taccagtcgc gttttacggt ttctggttta gctgtaaaag ttttcattaa aagcttaccc
    18121 aaataaataa gttacacgtt ggtgaacacc caaacgttta aatagttgag gttcacacga
    18181 caaagtccgg taaacctacc ccctcggata tgtttggccg gcacagagaa agtttgggaa
    18241 aaaactctct tgtaacgtgg ggtcgcagga ttatagagaa gtccaggtca aagatcgacc
    18301 cctttttgcg atttgccgcg ggttttgttc aggcctagtt caccctcggt cggggaggtt
    18361 gcacagatat aataccgcat aatgccggag cgctacgctt gtccggctta cggcatatgc
    18421 tcccgcttga gatactccgc actctgcatc tcttgcaggc gcgacagaca gcgctgaaat
    18481 tcaaacttga gtcgctcccc ctgataaatc tcatataacg gcgcggcggc gctgaccacc
    18541 agcttaacgt ggcgctcgta aaactcatcc accagcgcaa taaagcggcg cgcttcgttc
    18601 tccatcagcg gcgtcatgac cggcacgtca aacaacagaa ccgtgtgaaa taaccttgag
    18661 agcgcaatgt aatcatgctg gctgcgagcc tcgacgcaca gcgtagcgaa agaggccgct
    18721 aacgtttggt tttcaacgcc cagggtggat aaagggcgat gattgatttc cagcgtcgga
    18781 gcatgttctc gtgcggcccc cgctaacgcc agccacagtt tatccatttg ccgccgggtt
    18841 tcatcattaa gcggcgttag ccataaatgg gcctgcgtca gcgtccgcag ccggtaatcg
    18901 acgccggcgt ccacattcat aatgtcgcag tgctgtttaa tggcatcgat agccggcagg
    18961 aagcgggcgc gttgcaaacc gttgcggtag agttcctccg gcggaatatt ggaggtcgcg
    19021 accagcgtaa tgccgcgtgc aaacagcgct ttcattaaac cgcccagcag catggcgtcg
    19081 gtaatatcgg tgacgaaaaa ctcatcgaaa cacagtacgt ccgtctcggt tttaaaccga
    19141 tcggcaataa tgtctaacgg atcgatctgt ccctgtagcg cggtaagctc ttcatgcacg
    19201 cgcagcataa accgatgaaa atgcaggcgc aattttcgct cacccggcag gctgtggtag
    19261 aagagatcca tgagccaggt tttgccgcga cccacgcccc cccacatata cagcccgcga
    19321 accggtattt gcgcgtccgg ttcgtttttg cctaataatt tccccagtcg cgctatcaga
    19381 ccgccgggtg gcgtagccga cgattttttc gcggtgagcg cctgataaag ggtttccaga
    19441 cggtcgaccg cctctttctg tacgtcgtca ggctgatggg tgccttcgtt gagtgcctgg
    19501 agataacgcg atgtagggga aagactttgc ataatgttat tgttattcct tgaaaatcga
    19561 tgtgccgtcg ttcacggctg acgaaaaaaa ggccgttcta cactacgcga tatgctgtcg
    19621 ggattccact tctacgaaat tagcggttat agtggcataa tcaggcgcgg gcatggagcc
    19681 tggagccaac accctacgga aacataagac aacgggagat gttcatgacc tgggaatatg
    19741 cgctaattgg attagtcgtc ggtatcatca ttggtgccgt ggccatgcgt tttggtaatc
    19801 gtaagttacg tcaacagcag gcattgcagt acgaactgga aaaaaacaaa gctgagctgg
    19861 aagagtaccg tgaagagctg gttagccact ttgcccgcag cgcggaactg ctggatacca
    19921 tggcgcatga ttaccgccag ctgtatcagt atatggcgaa aagctccagc agcctgctgc
    19981 cggaaatgtc tgcggagtcg aatccgttcc gtaaccgtct ggcggagtct gaggcgagca
    20041 acgatcaggc gccagtacaa atgccacgtg attattctga aggcgcgtct ggcctgttac
    20101 gtagcggcgc aaagcgcgat taatcgcacg ccgttaagaa atttatcggg cgcatcgctt
    20161 gcgccctctc tctatctttc ctgtcccagc tattatcatt gttaccaggc tgaaaattca
    20221 ataacatcaa tctgttttga attgtctatc cgttcattca aggtacgaga gcagcatcca
    20281 tgaaaaaaca cacccagctg ttaagtgcat tagcgttaag tgtcggatta actctttcgg
    20341 caccgtttcc agcccttgca tcgataccag gccaggtgcc aggccaggcg acgctgccaa
    20401 gccttgcccc tatgctggag aaagtgctgc ctgctgtcgt cagcgtaaaa gtcgagggaa
    20461 ccgccaccca gagccaaaaa gtgccggagg agtttaaaaa attctttggc gaggatctgc
    20521 cagaccagcc gtcccagccg tttgaaggac tcggttcggg ggtgattatc gatgccgcga
    20581 aaggctatgt attaaccaat aatcatgtga ttaatcaggc acagaagatc agcattcaac
    20641 tgaatgacgg acgcgaattc gacgcgaagc tgatcggcgg cgacgaccag agcgatatcg
    20701 ctctgttaca aattcagaat cccagcaagt taacgcaaat tgccatcgcc gattccgaca
    20761 aactccgcgt cggcgatttc gccgtggcgg ttggtaatcc gtttggcctt ggacaaaccg
    20821 ccacctccgg gattatttca gcgctgggac gcagcgggct taatctggaa gggcttgaga
    20881 actttattca aaccgatgcc tctattaacc gcggcaactc cggcggcgcg ctgcttaacc
    20941 tgaacggcga gctgatcggg attaataccg caatcctcgc gccagggggc gggagcatcg
    21001 gcattggctt tgctattcct tccaatatgg cgcagacgct ggcgcagcag ttgattcagt
    21061 tcggcgaaat caaacgcgga ttgctgggaa ttaaaggcac tgaaatgacc gctgatatcg
    21121 ctaaggcatt caaactgaac gttcagcgtg gcgcttttgt cagcgaggtt ttacccaatt
    21181 caggttcggc gaaggccggg gtgaaatccg gagacgtgat tatcagtctt aacggtaagc
    21241 cgctgaatag ctttgccgaa ctgcgttcac gtatcgccac caccgaaccg ggcacgaaag
    21301 tgaagctggg cctgctgcgc gatggtaagc cgctggaggt ggaagtcacg ctggattcca
    21361 atacctcttc ttccgccagc gccgaaatga tcgccccggc gttgcaaggc gcgacgttga
    21421 gcgacggcca gctgaaagac gggacgaaag gcgttaaggt tgatagcgtc gaaaaaagca
    21481 gtcctgccgc gcaggccggt ttgcaaaaag atgatgttat catcggcgtt aatcgcgatc
    21541 gcatcagttc tatcgccgaa atgcgcaaag tgatggcggc aaaaccgtcc atcattgctc
    21601 ttcaggtagt acgcggcaac gagaacattt atctattgct gcgctaatcc tgtcttaaac
    21661 cgggcatcag cctgcgatgt gatgtccggt taactcatgg tatgctgctg ccgttccctt
    21721 ttttaacgac gcctccatca tgtttgtgaa gctcttacgt tcggtcgcaa taggtttaat
    21781 tgtcggcgct attctgttgg ccgtcatgcc ttctttgcgc aaaattaatc ctatcgccgt
    21841 cccgcaattc gacagtaccg atgagacgcc agccagttat aattttgcgg ttcgccgcgc
    21901 cgcgcctgcc gtcgtcaatg tctataaccg cagtatgaac agtaccgcgc ataatcaact
    21961 ggagatccgc acgctgggtt ccggcgtgat catggatcaa cgcggttata ttattaccaa
    22021 caagcacgtg attaacgatg ccgatcagat tatcgtcgcg ctacaggatg gccgcgtctt
    22081 tgaagcgcta ctggttggct ccgattcgct taccgacctg gcggtgctga agatcaacgc
    22141 cactggcggg ctgcctacca tcccgattaa tacaaagcgt acaccgcata ttggcgacgt
    22201 cgtactggct atcggcaacc catataatct gggacagacc atcacccagg ggatcatcag
    22261 cgcaacgggt cgtatcggcc tgaacccgac ggggcgacag aattttctcc agaccgacgc
    22321 ctcgattaac cacggtaatt ccggcggcgc gctggtcaac tcgttaggcg aactgatggg
    22381 gatcaacacc ctctcttttg ataagagtaa cgatggcgaa acgccggaag gccttggttt
    22441 tgcgattccc ttccagctag ccacgaaaat tatggataag cttatccgcg acggtcgcgt
    22501 gattcgcggc tatatcggta ttggcggacg agaaatcgcg ccgctgcacg cgcagcaggg
    22561 tagcggcatg gacccgattc agggcattgt cgttaatgaa gtaacgccaa acggccccgc
    22621 tgcgcttgcc ggtattcagg ttaatgattt gattatttcg gtcaataata aacccgccgt
    22681 gtccgcgctg gagacgatgg atcaggtggc ggaaattcgc ccgggctccg tcattccggt
    22741 cgtggtaatg cgggatgata agcagctcac gttccaggtg acggtgcagg aatacccggc
    22801 gtcaaactaa aacgacgcag cttttgcctg cgtcgttcga cggctagtca ataaagactg
    22861 gccctgccgg aaaatgcgcc aggaaactcg tgaagattag cagagcgggg aaactctttt
    22921 ccccgacggc ctcttcacgc agcgccttat cgagtgtcaa taagccagac tcgctccctt
    22981 cccccagaat gccgcccatc cagagcagtc gttgcgcctg ttgacgcgca tactgcgatg
    23041 cgcttttcca ggcgaccaga tgcagcaacg tttgtaacag caggacccga gacgcgtgac
    23101 catcgcgttg taatcgcctg aatacgggta atgcaatact acgcaccgtc gagaaaccgc
    23161 tcgccgcctc cccctcaatc ggcgataaac caacagccgc ctgtttgacg aaatcgcata
    23221 accgattgtg tgttaatggc cgctcgcctg cgctcatata ccctgcggcg aaacagagta
    23281 acccgatacc ctgagcccaa tcggtcgatg gcagaatccc ctgcggaaca ttcggtgccg
    23341 acgtctgtgc ggcacaaagc ccctcgtcgt aacactgtgc aaaacgttgc tcatatattg
    23401 ctgagttgac gccggaccac ggcagcaaat gcagcgctgg ctcaagctca gttatctgat
    23461 tcaccgtctc aacaacataa cgcaagatgg tttctctgga tggcatggat gtaccttgcc
    23521 gaaacgcaac catttcactc attactgtgt cctcattttg cgggagcata atcactgctc
    23581 ccgattagaa ttggattaca ttgccagcac gtacttcagc atcacgcccg ccgcaatggc
    23641 cgaaccgata accccggcca cgttcggccc catcgcgtgc atcagcagga agttctgcgg
    23701 gttcgactcc aggcccacct tgttcgacac cctggctgcc atcggcactg ccgacacccc
    23761 ggctgaacct atcagcgggt tgattttgtt cttactgcac aggttcagca gcttcgccat
    23821 cagcaccccg gccgccgtcc cgataccaaa ggcaatcacc cccagcagca gaatgcccag
    23881 cgtctgcggc tgcaggaact tatccgcgac cagcttcgcg cccaccgaca gcccgaggaa
    23941 aatggtcacg atattaatca gaccgttctg caccgtgtcg ctcagacgct ccaccacccc
    24001 gctttcacgc atcagattgc cgaagcagaa catccccagc agcggcgcgg cgtccggcag
    24061 cagcagggcc accagcagta acagcaccac cggaaagagg attttttccc gcttactcac
    24121 cgtgcgcagc tgcaccatgc ggattttgcg ctctttctcg ctggtcagcg cgcgcataat
    24181 cggcggctgg attaacggca ccagcgccat atacgagtag gccgccaccg caatggcccc
    24241 cagcagctcc ggtgccagct tgcccgacag ataaatcgcc gtcgggccgt ccgcgccgcc
    24301 gataatgccg atggccgccg cctgcggcag ggtgaaggca atcaggccga agtagttcag
    24361 cgtcagcgcc cccagtacgg tggcgaagat gccgaactgt gccgccgccc ccagcagcag
    24421 ggtgcgcgga ttggccagca gcgggccgaa gtcggtcatc gcgccgacgc ccataaagat
    24481 gaccagcggc gcgacgccgg agccaatcgc cactttatag aacagcgcca gcacccccgg
    24541 cgtgtagccc atgtccaccg ccagattttc catctggttc tggactgacg gcagggccag
    24601 cgccagcgct tccttgatgg cgtgcacgtc cggcgcgcag ttgagcttcg cggcaatcac
    24661 cgccagctgc ccggcgtcgt gatgggccag caggctctcc agcgcggtca gcgccatgcc
    24721 cgcttccggg atgttggaga gcaggccgcc gaagcctatc ggcagcagca gtaacggttc
    24781 gaactttttc gctatcgcca gccacagcaa cagcaggctg accagcagca tgatggcctg
    24841 gcccgcgcca aggtgcatca gccccatgcc ctgaagcagg gcgttcagac tttccatttc
    24901 agttctccgt tacgccagcg tcatcagggt gtcgcccacg gagacggcgt ccccggactt
    24961 caccgcgata ccgcggacgg tgccggcctg cgcggcgcgg atttcggttt ccatcttcat
    25021 ggcttccaga atcagcagca cgtcgccttc ggccacgctc tggccttcgg tggcaatcac
    25081 cttccagatg ttgcccgcca gcggcgcggt gaccggggtg ccggcgcctg ccggggcggc
    25141 agcctgaacc ggtgcggaag aggccgccgg aacagccgta gtaagctggc tgatatcgcc
    25201 gccgtcgctg accctcacca caaaggcttt gccttccact tccacggtgt agataccgga
    25261 ggcggcaggc ttctctgctt ttgccaccgg ctgcgcggct tccgcctgcg gcagtggctc
    25321 aaacgccgcc gggttatggc ggttctcaag gaatttgagg ccgatttgcg ggaacagcgc
    25381 cacggtgagc acgtcgtcga tggcgtttcc cgccagagta atccccttct cctgcgcctg
    25441 gcgcctgacg tccgcttcca gttcagccag ctccggcttc agcaggtccg ccgggcggca
    25501 ggtcaccgga gcgctccctt ccagcacgcg ggcctgtaac gcggcgttaa ccggcaccgg
    25561 ggtgtggccg tattcgcctt tcagaatgcc ggcggtttcc ttcgcgatgg ttttgtagcg
    25621 ttcgccggtc aggacgttga gcaccgcctg ggtgccgaca atctgcgagg tcggggtgac
    25681 cagcgggata aagccgaggt cctcgcgcac gcgggggatt tccgccagca cctggtccag
    25741 cctgtccgcc gcgttctgct gcttcagctg gctttcgagg ttggtcagca tcccgcccgg
    25801 tacctgcgcc accagaatac ggctgtcgta gcctttcagc tggccttcaa aggcatggta
    25861 ctttttgcgc acctcgcgga agtacgcggc gatattttcc agcttcagga tatccagccc
    25921 ggtgtcgtgc tcagtacctg ccaacgtcgc caccagcgcc tcggtggccg ggtggccgta
    25981 ggtggcgctc atggacgaaa tcgccgtgtc cacgccgtca acacccgcct cgatagcctt
    26041 cagcagggcc atctccgcca tcccggtggt ggcgtgacag tgcaggtgca ggcgcacctc
    26101 aaaacgtttt ttgatttcgc tcaccagctc aaaagcggcc atcggcgtga gaatgccgga
    26161 catatccttg atggcaatcg agtcaacgcc ggtctctaac aactgttcgg tcaggtccag
    26221 ccaggtctgc agggtgtgcg ccgggctggt ggtgtaggag agcgtcccct gggcgtgcgc
    26281 gccgtggctg cgcaccgcct gcagggcggc tttcatattg cgcgggtcgt tcatggcatc
    26341 gaagacgcgg aacacatcca tgccgttttt caccgcgcgt tcaacgaagc gctccaccac
    26401 atcatcggcg tagtggcggt agccgagcag gttctggccg cgcagcagca tctgcagcgg
    26461 ggttttgggc atggcttttt tgagttcgcg caggcgcagc cacgggtctt cgccgagaaa
    26521 acgaatacag gcgtcaaagg tggcgccgcc ccagcactcc agcgagccgt agcccacgtc
    26581 gtcgagctga gcggcaatcg gcagcatatc gtcaaggcgc aggcgggtgg cgaacagaga
    26641 ctggtgggcg tcacgcagga cgacgtcggt aatggcaata gtcatggatc cctccgggaa
    26701 ttaagcgtta aggcggtgat ggtgaatggc ggcggcaatc accggcttta agcgggtgaa
    26761 gtcgtccacg gcgggaacgg cgcgcggtgc gggcgcggcg acgggttccg ggaagaagcg
    26821 agtaatcacg gcagacatac cgcgaatggc aaagatcagc aggaacagaa agctcagtac
    26881 gaaccccatc cctaaaaaca tcagggtgaa accttcaccc agtaatacag cttcattcat
    26941 gaatcatttt ccataatgag aggcacgacg gtggccttga cgacaacctt cctggtgaat
    27001 ccggctaagg agtagagtgg atttcccttg gccacctctg gctttggcct ctacttttct
    27061 ccaggtcgtt tgcggcaaag acaccgccgt gcgttttttt acaccatcat gctgaacacg
    27121 atgctagcga taaccagcac aataccgccg cccagacgag aggaaatttg tgcatatgaa
    27181 atgaggttca tacggttaca ggcggagagc acttccagat cgccggagcc gccgcggttg
    27241 gccatacaaa gacccgcagt aatggatgat tcaatcgggt agaagccaat caaccagccc
    27301 ccgatagctg cgccaacgac agcgccgacc acaatgatcg cggcgataac gacgttcgcg
    27361 aacgtcaggg catcgatgat ctcttgcaga tcggtgtagc aaacacccac acctaccatc
    27421 agcacccaca gcagttgttt ggagaagaag tcagaaagac gtttcgcccc ggctttaatc
    27481 tccggtgagc aaagacctga tgcgttcagc gcagcaacaa tcaggaccat ccaggcgaag
    27541 tagtgaatag agacgccgcc gatgcttggc agaattttct tggcaacaac ataggccagc
    27601 aggaagcagg tggtggataa caccatgcca accgccgttt cacgatgggt aatctgaccg
    27661 gccttttcat catcttcggt tttgaaggaa gccttacgaa ccaattcacc ttcaccgcta
    27721 agccaggtgt attttttgcc tatcatatcg aggagggcgg cgaaaataat ggcgaagata
    27781 ttcgcaatgg tcagaatagc aatagccgtt gagtaatact cttcgcgaga acgtccggta
    27841 accgagtgat aaatttcaga cagaggcacg gcgcctgcgc cgttaccacc gcccataatc
    27901 ggcagaacgt atagcatcat gatacggtcg accgggatac cgaagcacaa accaatgacg
    27961 ataccgaaaa gggacgcgcc gacaatcccg gcgaggatgg ttgggatata gcccagcagt
    28021 gattttaata gcagcttacg gtttaccgac aggatcgcgc ctgtgatcaa cactgcgata
    28081 aacaggttaa ggaagttgct tttatccatt acgttgctga tcgcatcaat ttctttctgc
    28141 gtaaatatgc cagcatagac aaaataagct gcaaccagaa atatcataac cggtgcgccg
    28201 ccaatatatt tattgaagat cggtaaacgt ttgccgattt caccaaaaat ggcccccata
    28261 acaaacataa gagcaaaacc accgactaag tcagtcggta tagcattata gaaatgagac
    28321 agtaataaag taattaatgc aaaggcataa agcggtagcg gcataccaaa gattttgaat
    28381 ctgagtaaat cgctggcccc ctttttctcc gtcgccgaag cctgggtcat gttggtcata
    28441 aacattttcc tgtgtattga tgggtaacaa gacccgcgca tactaataaa ttcaatgaac
    28501 cgtgagatgt gactatcttc actgaatggt tgtgttttta attaatttaa ttatttttat
    28561 taactctggt taattaagga aataaaaacc ataaagctta taaaagcaag ggggaaagtg
    28621 tgatgtctat tccagacgag taatacaaac gctggcgaaa tatgcaacgt tatttgctga
    28681 cggatgcaga atagagtgaa tctaatattt aaacgcattt atttgcaaaa ggatgtattg
    28741 cgtcgcgagt cggtcgccat gtttctggag ggcgtgggac tcgccctgga agatgattgt
    28801 gaaatcgcgg tatgcgcata ttggcagggt gagatagttg gatgcggctc gctggccgga
    28861 aacgtactga aatgcatcgc cgtttccccg gttttacaag gggaagggct cagcctcaaa
    28921 ctgctgactg agctgcttac attggcctac gagttaaacc gcagcgagct tttcctgttc
    28981 actaagccgc aaaatcggtt gctgttttct ggcgcggggt tttggcccat tgcgcaggca
    29041 ggtgagctgg cggtgttaat ggagaacagc agtgaacggt tagcgcgctt ttgtcgccaa
    29101 ctggcgcttt atcgtcaacc gggaaaaacg atcggcgcca ttgtcatgaa cgccaatccg
    29161 tttaccttgg gccaccgtta tctggtggag caagcggctg cggcctgtga ctggttgcat
    29221 ctgtttgtag tcaaagaaga tgcttcattt ttttcctata ccgaccgttg ggcgctgatc
    29281 gaacaaggaa tcgcgggcat tgacaacgtc acgttgcatt ccggctccgc ttatatgatc
    29341 tcgcgtgcga cgtttcccgg ctatttcctc aaagaaaaag gggttgtgga cgactgccat
    29401 tgccagatcg atctgcaact cttccgtgaa catctggctc cagcgctggg gattacccat
    29461 cgttttgtcg gcagtgagcc gttttgtcct ctgacctgtg cctataacca gcggatgcac
    29521 gacattttac acgatccgaa gcgcagcggc ccggttattg aggtcgtcga gctggcgcgg
    29581 gtggagaaaa acggcacggc tatttccgcc tctcgcgtca gaaaactgta tagcgaacgt
    29641 aattggccgg caataagcgc gctggtgcct gctggcaccc tggcatatct gcagcggcat
    29701 gccgccagac acactgaaac catatgacgt aacaccgtta acaaggaaca taactaatga
    29761 aaatcattaa agatgccctg gcaggcacgc tggaatccag cgatgtgatg atcaggattg
    29821 gtccatccag cgagccagga attcggctgg agctagagag tctggtgaag cagcagtttg
    29881 gcgcggcgat tgagcaggtg gttcgggaaa cgctggcgaa gctgggcgtt gaacgcgcgc
    29941 tggttagcgt cgatgacaaa ggcgcgctgg agtgtatttt acgcgcccga gtgcaggcgg
    30001 cggcgttacg cgctgcagaa caaacggaaa ttcaatggag tgcgttatga gacctcgtcg
    30061 cagtatgttg tttatccccg gcgcaaatgc ggccatgttg agcacctcgt ttgtctatgg
    30121 tgcggacgcg gtgatgttcg acttagaaga cgccgtagca ttacgtgaga aagataccgc
    30181 ccgtctttta gtccatcacg cgcttcaaca tccgttctat caggatgttg aaaaagtggt
    30241 gcgcattaat ccactgaaca cgccattcgg tctggccgat cttgaggccg tcgtgcgtgg
    30301 tggcgcggat atcgtgcgtc tgccgaaaac cgacagcaaa aacgatgtgc tggagctgga
    30361 agcgcaggtt gaacggatcg aacgtgaatg tggacgtgaa gtcggcagta ccaggctgat
    30421 ggcggcgatc gaatcagcga aaggcgtggt caatgccgtc gacatcgcca cctccagccc
    30481 gcgcatggtg gcaattgcgc tggcggcatt tgattacgtg atggatatgg gcaccagccg
    30541 gggcgatggc accgagctgt tctacgcccg ctgcgcagtg ctgcatgcgg cgcgcgttgc
    30601 gggtattgcc gcctatgatg tcgtttggtc ggatatcaat aatgaagaag gcttcctgaa
    30661 ggaagtgcag ttggcgaaag ggcttggttt taacggtaag tccttagtga atccacgtca
    30721 gattgagctg ttacatcagg cttattctcc gacgcgtaaa gaagttgagc atgcgcacga
    30781 ggtgattgcc gccgctgaag aggctgagtc tcgcggtctg ggcgtcgttt cactcaacgg
    30841 caaaatgatt gacggcccga ttatcgacca cgcgcgcaaa gtggtggcgc tgtcggcttc
    30901 cggtattcgt gattaaggaa ggaaccatga aagagactgt aactatgctc aatcagcaat
    30961 atgtcgtacc ggaaggatta caaccctacc agggggtaac agtgaatagc ccgtggcttg
    31021 ccagtgaaac ggaaaagcgt cggcgtaaaa tttgtgactc gcttgaagag gctatccgtc
    31081 gttccgggct taaaaatggc atgacgatat ccttccacca tgcgtttcgt ggtggcgaca
    31141 aagttgtcaa tatggtgatg gcgaaactgg cggaaatggg attccgcgat ctgacgcttg
    31201 cctccagctc gttaatcgat gcccactggc cgcttatcga acacattaaa aatggcgtgg
    31261 tgcggcagat ttacacctct gggctgcgcg gcaagttagg ggaagagatc tccgctggcc
    31321 tgatggaaaa cccggtacag atccactctc acggcggccg cgtaaaactg attcagagcg
    31381 gtgagctgaa tattgatgtc gctttcctcg gcgtgccgtg ctgcgacgaa tttggtaatg
    31441 cgaacggttt tagcggcaag tcacgctgcg gctctttggg gtatgcgcag gttgatgcgc
    31501 agtacgctaa atgtgtggtg ctcctgactg aagagtgggt cgagttcccc aattatccgg
    31561 ccagtatcgc gcaggatcag gttgatttga tcgtacaggt ggacgaagta ggggatccgg
    31621 aaaaaatcac tgcgggcgcg attcgtctgt ccagcaaccc gcgtgaactg ttgatcgccc
    31681 ggcaggcggc caatgtgatc gaacactcgg gttatttttg tgacggtttc tcgctgcaaa
    31741 ccggcaccgg tggcgcttct ctggcggtca cccgtttcct ggaagacaaa atgcgtcgcc
    31801 acaacattac ggcgagtttt ggcctgggcg ggatcaccgg caccatggtg gatctgcatg
    31861 agaaagggtt gatcaaagcg ctgctggata cgcaatcatt cgatggcgat gcagcccgtt
    31921 cgctggcgca gaacccgcat catattgaaa tttcaaccaa tcaatacgcg aaccccggct
    31981 ctaaaggcgc ggcatgcgaa cgcctgaatg tggtgatgct gagcgcgctg gaaattgacg
    32041 tgaatttcaa cgttaacgtg atgaccggtt caaacggcgt actgtgtggc gcatcgggcg
    32101 gccatagcga tacggcagca ggggccgatc tcaccattat taccgcaccg ctggtgcgcg
    32161 ggcgtattcc ttgcgtggta gaaaaagtgc tgactaccgt cacgctaggg gcaagcgttg
    32221 atgtgctggt taccgaccat ggtattgcgg tgaaccctgc gcgtcaggat ctgcttgata
    32281 acctgcgtgc tgcgggcgtg gcgctgatga ccatcgaaca actgcaacag cgcgccgagc
    32341 aactgaccgg taaaccgcag ccgattgagt ttaccgatcg ggtggtggct gtggtgcgtt
    32401 atcgcgacgg ttcagtgatt gacgtgattc gccaggttaa aggctgatga agggcacaga
    32461 cctgctgtac cagggccagg cagttacgct ggaggagatg ctacaagcgc gcgataaacg
    32521 tgccgccagg cagcgtcagg cgttgaactg ctatcggcta ccgttgattt ccctcacgct
    32581 ggttgcaccg ggcgccgtta aaaactcagc ggtctggcgg cgtgtcgccg attacgcaat
    32641 tgccgaaata ctggcgcttt gcgaacagaa ggagtgggtc aacgtctggg aaatgcaggt
    32701 aaatgaacgc agcggcccgg aatggatggc agcggtctgt gcgccggcaa tggcgttgaa
    32761 acagcacatg tcgacactag agatgagcca tccgttaggg cggctttggg acatcgacat
    32821 tattgatagc gacggtaagt cgctatcacg ccgtgaactc gggcatcctg cccggccatg
    32881 tttgatatgc cagcaggatg ctcatctctg tgcccggggc aagcatcaca cccttgacct
    32941 tttgttggat gaaattgcac gaaggattga atgctatgaa cgtgagcgtt gtgactgaac
    33001 ggcgtacgcc agcgtactca tcgctggcgg ctggcgaact taatgggttg gttgcaagag
    33061 cgctgctgac ggaagccagg ctgacaccaa aacccggtct ggtcgatatt cgtaattcgg
    33121 gagcgcatag ggatatggat ctggcggcat ttgaacgtag cactaccgcc attgctccgt
    33181 ggatggaaaa gttttttatc atgggcaaca acacggcggc gctggcggca gaaaatgtcc
    33241 tggtgatgct gcgtccgctg gggatggcct gtgagaacga tatgctacag gcgaccaatg
    33301 gtgtgaatac ccatcgcggg gcgattttcg cttttggcct gctgagcgca gcgattggcc
    33361 gacttctcgc gcggggagaa ccgttggagc aaaatcgtat ctgcgaccag gttgctcgcc
    33421 tgagtcggaa tattgttgcc cacgagctct cagcaagaaa agcgggaaaa ctgacaaaga
    33481 gtgaaaccca tttccagtgt tatggcctgt cgggcgcgcg gggagaagcg gaaagcggtt
    33541 ttcgaaccgt cagaacgcag gctttgccgg tgtttaaccg ggtcgtgcag gagcatgacg
    33601 atacccatct tgccctgctg caaacattgt tgcatctgat ggcgtggaat gatgatacca
    33661 atctggtgtc acggggaggc ctggaagggc tttactacgt gcagcagcag gcacaaaaat
    33721 tgttgtggca agggggcgta ttggttgagg ggggcattga agcgatgcag ttcctcgatg
    33781 atgaactcat cctgcgtaac ttaagccctg gcggtagcgc ggatttactg gcagtgacct
    33841 ggtttttaag tcattttcct gccggttccc tctatcctga gtaagtttct cttctttcat
    33901 tctctccagc aatgattcat cctgtgggat gaatcatgtc ttttactgat atcgctccct
    33961 gtttatcatt aatttctaat tatcggcgat tttagatggc ggcctccggg cgcgctggtt
    34021 actctgaaaa cggtttacgc aatttttaca aaagagaata gctatgcatg aagcacaaat
    34081 ccgcgtcgcc attgccggcg ccggtggccg catgggacgg cagttaatcc aggccgccat
    34141 ggcgatggaa ggtgttcagc tgggtgccgc gctggagcgc gaaggctctt ccttgctggg
    34201 cagcgatgct ggcgaactgg cgggggcggg aaagtccggc gtgatcgttc aaagcagcct
    34261 tgaggcggta aaagatgatt ttgacgtttt catcgatttt acccgtccgg aaggcacgtt
    34321 gacgcatctg gcgttttgcc gccagcatgg taaagggatg gtgattggta ctaccggctt
    34381 tgacgacgcc ggtaaacagg ccattcgtga ggcgtcgcaa gagattgcga tcgttttcgc
    34441 cgcaaacttt agcgtcggcg ttaacgtcat gctcaagctg ctggagaaag ccgcgaaggt
    34501 aatgggcgac tatagcgata ttgaaattat tgaagcgcac caccgccata aagtggatgc
    34561 accgtcgggg acagcgctgg caatgggcga ggcaatcgcc ggggcgctgg ataaagatct
    34621 gaaggactgc gcggtctact cgcgtgaagg ttataccggc gagcgcgtac cgggaacgat
    34681 tggctttgca accgttcggg cgggcgacat cgtcggcgaa cataccgcga tgtttgccga
    34741 tattggcgag cgcgtagaga ttacgcataa agcttccagc cgcatgacgt ttgcaaatgg
    34801 cgcgttgcga tcggcgttat ggctaaaaac gaagaaaaat gggctatttg acatgcggga
    34861 tgtgctgggg ctggatgtat tatagcgact aaataccttc gtgatgtggt tgtggtaatc
    34921 aagattaatt gattacaaag ggcaatatat tattgccctt ttgtttttgc ccctcggtta
    34981 ttcggtcaga taaataacgc ctttcaccat tcatgtttcg acagtttctt ctcccacgac
    35041 atgttctgcc gcagtggctt accgtatgca aaaggcacct cgaccagact gataagactg
    35101 atatccattg gggggttagt gctgttccac gggatcgttt tatctctttt gcttcaataa
    35161 gttagctttt ttatgctgta
//
LOCUS       DAJVBX010000018        34889 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.018, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000018 DAJVBX010000000
VERSION     DAJVBX010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 34889)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34889)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34889
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.018"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            73..315
                     /locus_tag="OPV72_000817"
     CDS             73..315
                     /locus_tag="OPV72_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein"
                     /protein_id="HCR9913189.1"
                     /translation="MKKVLYGIFAITALAATSVSAAPVQVGEAAGSAATSVSAGSSSA
                     TSVSTVSSAVGVALAATGGGDGSNTGTTTTTTTSTQ"
     gene            379..1017
                     /locus_tag="OPV72_000818"
     CDS             379..1017
                     /locus_tag="OPV72_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbF family lipoprotein"
                     /protein_id="HCR9913190.1"
                     /translation="MKRLALILICLLLQACSATTKGLGDSLWDSLFGTPGVQLTDDDI
                     QNMPYASQYMQLNGGPQLFVVLAFSENGQQKWVTQDGATIVTQHGRLVKTLLGGDNLI
                     DVNNLATDPLAKPGQIIDGATWTRTLGWTEHRQVRYATARSVFTWRGTDRVNVGSEET
                     AVRVLDEEVTTDQTRWRNRYWVDSEGQIRQTEQYLGANYFPVKTTLIKAAKS"
     gene            1014..1748
                     /locus_tag="OPV72_000819"
     CDS             1014..1748
                     /locus_tag="OPV72_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsule biosynthesis GfcC family protein"
                     /protein_id="HCR9913191.1"
                     /translation="MMKRTISALALAFVASSAFASGTVTVFTQGNSEPKTLTDAERLL
                     DLVGQPRLATSWWPAAVIGEEQATVTARQQQQELLGRLAALSAEEDGDAAAINTLRRQ
                     IQAVKVTGRQFVNLDPDVVRVSERGNPPLQGHYTLWVGPQPTQVTLFGLISQPGSQPF
                     VPGRDVASYLEGQRLLSGADRSYAWVVYPDGRSQKAPVAYWNKRHIEPMPGSIIFVGF
                     ADSLWRGTPEAINADILHTLTQRIPE"
     gene            1748..3844
                     /locus_tag="OPV72_000820"
     CDS             1748..3844
                     /locus_tag="OPV72_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbH domain-containing protein"
                     /protein_id="HCR9913192.1"
                     /translation="MKKTHLLSVLALGISAACHAETYPAPVGPSQSDFGGVGLLQTPT
                     ARMAREGEMSLNYRDNDQYRYYSASVQLFPWLETTLRYTDVRTKKYSSVESFSGDQTY
                     KDKAFDVKLRLWEESYWMPQVAVGARDIGGTGLFDAEYIVASKAWGPFDFSLGLGWGY
                     LGTSGNVSNPFCSYSDKFCSRDNSYKEAGSVDGSDMFHGPASLFGGVEYQTPWQPLRL
                     KLEYEGNNYQQDFAGKLEQKSKFNVGAIYCVTDWADVNLSYERGNTFMFGVTLRTNFN
                     DLRPAYHDNSRPQYRPQPQDAILQHSVVANQLTLLKYNAGLADPKIQVKGDTLYVTGE
                     QVKYRDSREGIVRANRIVMNDLPEGIRTIRVTENRLNLPQVTTETDVASLKRHLEGEP
                     LGHETPLAQKRVEPIVPESTEQGWYIDKSRIDFHLDPVLNQSVGGPENFYMYQLGVMG
                     TADLWVTDHLLTTGSVFANIANNYDKFNYTNPPKDSHLPRVRTHVREYVQNDVYVNNL
                     QANYFQYFGNGFYGQVYGGYLETMFGGAGAEVLYRPVDSNWAFGLDANYVKQRDWRSA
                     QDMMKFTDYSVKTGHLTAYWTPSFAQDVLVKASVGQYLAGDKGGTLEIAKRFDSGVVV
                     GGYATITDASPDEYGEGDFTKGVYVSVPLDLFSSGPTRSRAAIGWTPLTRDGGQQLGR
                     KFGLYDMTSDRSVNFR"
     gene            3987..4397
                     /gene="psiE"
                     /locus_tag="OPV72_000821"
     CDS             3987..4397
                     /gene="psiE"
                     /locus_tag="OPV72_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-starvation-inducible protein PsiE"
                     /protein_id="HCR9913193.1"
                     /translation="MMPLSRSRLEFIATILQNVLNLGLLTLGLILVVFLGKETVHLAD
                     ALFAPEQASKYELVEGLVIYFLYFEFIALIVKYFKSGLHFPLRYFVYIGITAIVRLII
                     VDHKTPMDVLLYSAAILLLVITLWLCNSNRLRRE"
     gene            complement(4563..5453)
                     /gene="malG"
                     /locus_tag="OPV72_000822"
     CDS             complement(4563..5453)
                     /gene="malG"
                     /locus_tag="OPV72_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose ABC transporter permease MalG"
                     /protein_id="HCR9913194.1"
                     /translation="MAMVQPKSQKLRLFITHLGLLIFIAAIMFPLLMVIAISLREGNF
                     ATGSLIPDKISWEHWRLALGFSVEHADGRVTPPPFPVLLWLWNSVKIAGITAIGIVAL
                     STTCAYAFARMRFPGKATLLKGMLIFQMFPAVLSLVALYALFDRLGQYIPFIGLNTHG
                     GVIFAYLGGIALHVWTIKGYFETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVV
                     FILSFIAAITEVPVASLLLRDVDSYTLAVGMQQYLNPQNYLWGDFAAAAVLSAIPITL
                     VFLLAQRWLVNGLTAGGVKG"
     gene            complement(5468..7012)
                     /gene="malF"
                     /locus_tag="OPV72_000823"
     CDS             complement(5468..7012)
                     /gene="malF"
                     /locus_tag="OPV72_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose ABC transporter permease MalF"
                     /protein_id="HCR9913195.1"
                     /translation="MDVIKKKHWWQSDQLKWSVIGLLGLLVGYLVVLMYVQGEYLFAI
                     MTLILSSAGLYIFANRKTYAWRYVYPGLAGMGLFVLFPLVCTIAIAFTNYSSTNQLTF
                     ERAQQVLMDRSYQAGKTYNFGLYPAGDEWQLALTDGETGKHYLSGAFSFGGEQKLQLK
                     ETDALPGGERANLRIITQNRLALNQITAVLPDESKVVMSSLRQFSGTRPLYTLADDGL
                     LTNNQSGVKYRPNNDSGYYQSINADGSWGDEKLSPGYTVTIGAKNFTRVFTDEGIQKP
                     FFAIFVWTVVFSVLTVVLTVAVGMVLACLVQWEALKGKAIYRVLLILPYAVPSFISIL
                     IFKGLFNQSFGEINMMLSALFGIKPAWFSDPNTARAMVIIVNTWLGYPYMMILCMGLL
                     KAIPDDLYEASAMDGAGPFQNFFKITLPLLIKPLTPLMIASFAFNFNNFVLIQLLTNG
                     GPDRLGTTTPAGYTDLLVSYTYRIAFEGGGGQDFGLAAAIATLIFLLVGALAIVNLKA
                     TRMKFD"
     gene            complement(7144..8334)
                     /gene="malE"
                     /locus_tag="OPV72_000824"
     CDS             complement(7144..8334)
                     /gene="malE"
                     /locus_tag="OPV72_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose/maltodextrin ABC transporter
                     substrate-binding protein MalE"
                     /protein_id="HCR9913196.1"
                     /translation="MKIKTGVGILALSALTTMMISAPALAKIEEGKLVIWINGDKGYN
                     GLAEVGKKFEQDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLL
                     AEVTPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLVPNPPKTWEEIPA
                     LDKELKAKGKSAIMFNLQEPYFTWPLIAADGGYAFKFENGKYDVKDVGVDNAGAKAGL
                     TFLIDMIKNKNMSADTDYSIAEAAFNKGETAMTINGPWAWSNIDKSKVNYGVTLLPTF
                     KGKPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDQGLEAVNKDKPLGAVALKSFQ
                     EQLAKDPRIAATMDNAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDAALKDAQS
                     RITK"
     gene            8696..9805
                     /gene="malK"
                     /locus_tag="OPV72_000825"
     CDS             8696..9805
                     /gene="malK"
                     /locus_tag="OPV72_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011915502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose/maltodextrin ABC transporter ATP-binding
                     protein MalK"
                     /protein_id="HCR9913197.1"
                     /translation="MASVQLRNVTKAWGDVVVSKDINLDIHDGEFVVFVGPSGCGKST
                     LLRMIAGLETITSGDLFIGETRMNDIPPAERGVGMVFQSYALYPHLSVAENMSFGLKL
                     AGAKKEVMNQRVNQVAEVLQLAHLLERKPKALSGGQRQRVAIGRTLVAEPRVFLLDEP
                     LSNLDAALRVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKP
                     LELYHYPADRFVAGFIGSPKMNFLPVKVTATAIEQVQVELPNRQQIWLPVESRGVQVG
                     ANMSLGIRPEHLLPSDIADVTLEGEVQVVEQLGHETQIHIQIPAIRQNLVYRQNDVVL
                     VEEGATFAIGLPPERCHLFREDGSACRRLHQEPGV"
     gene            9895..11253
                     /locus_tag="OPV72_000826"
     CDS             9895..11253
                     /locus_tag="OPV72_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltoporin"
                     /protein_id="HCR9913198.1"
                     /translation="MMITLRKLPLAVAVAAGVMSAQAMAVDFHGYARSGIGWTGSGGE
                     QQCFQVTGAQSKYRLGNECETYAELKLGQEVWKEGDKSFYFDTNVAYSVNQQNDWEST
                     DPAFREANVQGKNLIEWLPGSTIWAGKRFYQRHDVHMIDFYYWDISGPGAGIENIDLG
                     FGKLSLAATRSTEAGGSYTFSSQNIYDEVKDTANDVFDVRLAGLQTNPDGVLELGVDY
                     GRANTTDGYKLADGASKDGWMFTAEHTQSMLKGYNKFVVQYATDAMTTQGKGQARGSD
                     GSSSFTEELPDGTKINYANKVINNNGDMWRILDHGAISLGDKWDLMYVGMYQNIDWDN
                     NLGTEWWTVGVRPMYKWTPIMSTLLEVGYDNVKSQQTGDRNNQYKITLAQQWQAGDSI
                     WSRPAIRIFATYAKWDEKWGYIKDGDNISRYAAATNSGISTNSRGDSDEWTFGAQMEI
                     WW"
     gene            11417..12334
                     /gene="malM"
                     /locus_tag="OPV72_000827"
     CDS             11417..12334
                     /gene="malM"
                     /locus_tag="OPV72_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose operon protein MalM"
                     /protein_id="HCR9913199.1"
                     /translation="MKMKKSLVALCLTAGLFASVPGISLAEVNYVPQNTSAAPAIPAA
                     ALQQLTWTPVDQSKTQSTQLATGGQRLDVAGITGPVAAYSVPANIGELTLTLTSEVNK
                     QASVFAPNVLILDQNMTPSAFFPSSYFTYQQPGVMSADRLEGVMRLTPALGQQKLYVL
                     VFTTEKDLQQTTTLLDPAKAYAKGVGNSIPDIPDPVARHTTDGVVKLKVKTNSSSSVL
                     VGPLFGSSGTGPVTVGNTAAPVAAPAPVAPKKSEPMLNDTESYFNKAIKDAVAKGDVD
                     KALKLLDEAERLGSTSARSTFISSVKGKG"
     gene            12515..13012
                     /gene="ubiC"
                     /locus_tag="OPV72_000828"
     CDS             12515..13012
                     /gene="ubiC"
                     /locus_tag="OPV72_000828"
                     /EC_number="4.1.3.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate lyase"
                     /protein_id="HCR9913200.1"
                     /translation="MSHPALTQLRALRYFDAIPALEPHLLDWLLLEDSVTKRFEQQGK
                     RVSVTLIREAFVGQSEVEEASGLLPSESRYWLREILLCADGEPWLAGRTVVPESTLCG
                     PEQVLQHLGKTPLGRYLFTSSTLTRDFIEIGRDATLWGRRSRLRLSGKPLLLTELFLP
                     ASPLY"
     gene            13026..13898
                     /gene="ubiA"
                     /locus_tag="OPV72_000829"
     CDS             13026..13898
                     /gene="ubiA"
                     /locus_tag="OPV72_000829"
                     /EC_number="2.5.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybenzoate octaprenyltransferase"
                     /protein_id="HCR9913201.1"
                     /translation="MEWSLTQSKLLAFHRLMRTDKPIGALLLLWPTLWALWVATPGMP
                     QLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTVNRPLPSGAVTEKEARNLFVV
                     LVLLAFLLVLTLNAMTILLSVAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAA
                     VSESLPLSCWLMFLANILWAVAYDTQYAMVDRDDDIKIGIKSTAILFGRYDTLIIGIL
                     QLGVMALMALIGWLNGLGWGYYWAVLVAGALFVYQQKLIANREREACFKAFMNNNYVG
                     LVLFLGLAMSYWHF"
     gene            complement(13997..16417)
                     /gene="plsB"
                     /locus_tag="OPV72_000830"
     CDS             complement(13997..16417)
                     /gene="plsB"
                     /locus_tag="OPV72_000830"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsB"
                     /protein_id="HCR9913202.1"
                     /translation="MSGWPRIYYKLLNLPLSILVKSKSIPAEPAQELGLDTSRPIMYV
                     LPYNSKADLLTLRAQCLAHDLPDPLEPLEIDGALLPRYVFIHGGPRVFTYYTPKEESV
                     KLFHDYLDLHRSNPALDVQMVPVSVMFGRAPGREKGEENPPLRMLNGVQKFFAISWLG
                     RDSFVRFSPSVSLRRMADEHGTDKIIAQKLARVARMHFARQRLAAVGPRLPARQDLFN
                     KLLASKAIARAVEDEARSKKISHEKAQQNAIALMEEIAANFSYEMIRLTDRILGFTWN
                     RLYQGINVHNAERVRQLAHDGHEIVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGIN
                     LNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFSRGYSVEYFVEGGRSRTG
                     RLLDPKTGTLSMTIQAMLRGGTRPITLVPIYIGYEHVMEVGTYAKELRGATKEKESLP
                     QMLKGLSKLRNLGQGYVNFGEPMPLMTYLNQHVPEWRESIDPIEAIRPAWLTPTVNSI
                     AADLMVRINNAGAANAMNLCCTALLASRQRSLTREQLTEQLDCYLDLMRNVPYSTDST
                     VPAASAGELIAHALQMNKFEVEKDTIGDIIILPREQAVLMTYYRNNIAHMLIMPSLMA
                     AIITQHRRISRDALQQHVEALYPMLKAELFLRWEREELASVIDALASEMQRQGLITLQ
                     DDELHINPTHSRTLQLLAAGARETLQRYAITFWLLSANPSINRSTLEKESRTVAQRLS
                     VLHGINAPEFFDKAVFSSLVLTLRDEGYISDTGDAEPAETMKIYQMLADLITSDVRLT
                     IESATQGE"
     gene            16588..16956
                     /locus_tag="OPV72_000831"
     CDS             16588..16956
                     /locus_tag="OPV72_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HCR9913203.1"
                     /translation="MANNTTGFTRIIKAAGYSWKGFRAAWTHEAAFRQESLAVLLGVI
                     IACWLDVDAITRVLLIGSVLLIMIVEILNSAIEAVVDRIGSEYHELSGRAKDMGSAAV
                     LLSIFVALMTWGILLWSHFR"
     gene            17065..17673
                     /gene="lexA"
                     /locus_tag="OPV72_000832"
     CDS             17065..17673
                     /gene="lexA"
                     /locus_tag="OPV72_000832"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repressor LexA"
                     /protein_id="HCR9913204.1"
                     /translation="MKALTARQQEVFDLIRDHISQTGMPPTRAEIAQRLGFRSPNAAE
                     EHLKALARKGVLEIVSGASRGIRLLQEEEDGLPLVGRVAAGEPLLAQQHIEGHYQVDP
                     SLFKPSADFLLRVSGMSMKDIGIMDGDLLAVHKTQDVRNGQVVVARIDDEVTVKRLKK
                     QGNKVELLPENSEFTPIVVDLREQSFTIEGLAVGVIRNGEWL"
     gene            17852..19177
                     /gene="dinF"
                     /locus_tag="OPV72_000833"
     CDS             17852..19177
                     /gene="dinF"
                     /locus_tag="OPV72_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter DinF"
                     /protein_id="HCR9913205.1"
                     /translation="MPLFTSSDKALWRLALPMIFSNITVPLLGLVDTAVIGHLDSPVF
                     LGGVAVGATATSFLFMLLLFLRMSTTGLTAQAFGAKNPQALARALIQPLLLALGAGVM
                     IVLFRTPLIELALHIVGGNDAVLVQARRFLEIRWLSAPASLANLVLLGWLLGVQYARA
                     PVILLVVGNILKIALDLWLVMGLHMNVQGAALATVIAEYVTLLIGLMMVRKVLHLRGV
                     SLDMLKQAWRGNVRRLLALNRDIMLRSLLLQLCFGAITVSGARLGSDIIAVNAVLMTL
                     LTFTAYALDGFAYAVEAHSGQAYGARDGSKLLDVWRAACRQSGIVALLFSTVYALAGE
                     HIVALLTSLPQIQLLADRYLIWQVVLPLVGVWCYLLDGMFIGATRAAEMRNSMAVAAG
                     GFALTLFALPVLGNHGLWLALTVFLALRGLSLSLIWRRHWREGTWFARS"
     gene            19174..19287
                     /locus_tag="OPV72_000834"
     CDS             19174..19287
                     /locus_tag="OPV72_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913206.1"
                     /translation="MMVKNSEYKTEGRIPAYNYYHVQQKLQCIWANNTCYS"
     gene            19309..19518
                     /locus_tag="OPV72_000835"
     CDS             19309..19518
                     /locus_tag="OPV72_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HCR9913207.1"
                     /translation="MNKDEAGGNWKQFKGKMKEQWGKLTDDDMTVIEGKRDQLVGKIQ
                     ERYGYQKDQAEKEVVDWETRNNYRW"
     gene            complement(19618..20133)
                     /gene="zur"
                     /locus_tag="OPV72_000836"
     CDS             complement(19618..20133)
                     /gene="zur"
                     /locus_tag="OPV72_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc uptake transcriptional repressor Zur"
                     /protein_id="HCR9913208.1"
                     /translation="MEKTTTQELLAQAEKLCAQRNVRLTPQRLEVLRLMSLQQGAISA
                     YDLLDLLRETEPQAKPPTIYRALDFLLEQGFVHKVESTNSYVVCHLFDQPTHSSAMFI
                     CDRCGVVKEECAEGVEDIMHTLAAKMGFALRHNVIEAHGLCPACVEVEACRHPGDCGH
                     DHSVLVKKKPR"
     gene            20380..21690
                     /locus_tag="OPV72_000837"
     CDS             20380..21690
                     /locus_tag="OPV72_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraF"
                     /protein_id="HCR9913209.1"
                     /translation="MNKNVKLSLIAIAVSLFMTKQAGAANTWTEARNDAMGGTGVASA
                     NYGSGVLLNPALLAKAKPEDNITVVLPAVGVQITDKDNLQDEIDDISDKVDYYDEVVD
                     NLTLGQILLNPRGVLNQFQGAARDLADELEYLNGKTARANAGAGLAVSIPGQTLSVAF
                     IAKGYAHGRVSSSIDQNDIQYLRDIQHDERVALREAGRAALLGSDEITKHLNSTALGR
                     VAIVSDYGIALAKQFVVGEVPVSIGVTPKLQKTWLYNYTTSIYNYDSSDWNSSRYRND
                     DTGFNIDAGLAADIGENWTLGLSGQNLVSRDIDTKDIYITNGMTGETTNYKETYQIRP
                     LVTAGIAWHNDLLTVSADGDLTETKGFKSEDNSQYVGVGAEVRPLSWLAVRAGYRADV
                     KNNDSNVVTGGLGFAPFNRAHLDLMGLYGEDETWGAGAQLTMTF"
     gene            21778..22776
                     /gene="dusA"
                     /locus_tag="OPV72_000838"
     CDS             21778..22776
                     /gene="dusA"
                     /locus_tag="OPV72_000838"
                     /EC_number="1.3.1.-"
                     /EC_number="1.3.1.91"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine(20/20a) synthase DusA"
                     /protein_id="HCR9913210.1"
                     /translation="MQPETQSSALPAYRFSIAPMLDWTDRHCRYFLRLLSRQTLLYTE
                     MVTTGAIIHGKGDYLAYSEEEHPVALQLGGSDPAQLAHCAKLAEARGYDEINLNVGCP
                     SDRVQNGMFGACLMGNAQLVADCVKAMRDVVSIPVTVKTRIGIDDQDSYAFLCDFINT
                     VSGQGECEMFIIHARKAWLSGLSPKENREIPPLDYPRVYQLKRDFPHLTMSINGGIKS
                     LEEAKEHLRHMDGVMVGREAYQNPGILAAVDREIFGADTTDTDPVAVVRAMYPYIERE
                     LSQGAYLGHITRHMLGLFQGIPGARQWRRYLSENAHKAGADAAVLEQALKLIADKR"
     gene            22944..23186
                     /gene="pspG"
                     /locus_tag="OPV72_000839"
     CDS             22944..23186
                     /gene="pspG"
                     /locus_tag="OPV72_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response protein PspG"
                     /protein_id="HCR9913211.1"
                     /translation="MLELLFVLGFFLMLMVTGVSLLGILAALVVATAVMFLGGMFALM
                     IKLLPWLLLAVAVVWVIKAVKTPKIPQYQRNNRRFY"
     gene            complement(23361..24344)
                     /locus_tag="OPV72_000840"
     CDS             complement(23361..24344)
                     /locus_tag="OPV72_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinone oxidoreductase"
                     /protein_id="HCR9913212.1"
                     /translation="MATRIEFHKHGGPEVLQTVEFTPTEPAEHEIQVENKAIGINFID
                     TYIRSGLYPPPSLPAGLGTEAAGVVSKVGSGVEHIRVGDRVVYAQSTLGAYSSVHNVP
                     ADKAAILPDAISFEQAAASFLKGLTVFYLLRKTYEVKPDEPFLFHAAAGGVGLIACQW
                     AKALGAKLIGTVGSAQKAQRALDAGAWQVINYREESIVERVKEITGGKKVRVVYDSVG
                     KDTWEASLDCLQRRGLMVSFGNASGPVTGVNLGILNQKGSLYATRPSLQGYITTREEL
                     TEASNELFSLIASGVIKVDVAENQRYALKDARRAHEVLESRATQGSSLLIP"
     gene            24409..25824
                     /gene="dnaB"
                     /locus_tag="OPV72_000841"
     CDS             24409..25824
                     /gene="dnaB"
                     /locus_tag="OPV72_000841"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HCR9913213.1"
                     /translation="MAGNKPFNKPQTDARDRDPQVAGIKVPPHSIEAEQSVLGGLMLD
                     NERWDDVAERVVAEDFYTRPHRHIFTEMGRLQESGSPIDLITLAESLERQGQLDSVGG
                     FAYLAELSKNTPSAANISAYADIVRERAVVRDMIAVAHEIADAGYDPQGRNSDELLDL
                     AESRVFQIAENRANKDEGPKSIDQILDATVARIEQLFQQPHDGVTGVDTGYQDLNKKT
                     AGLQRSDLIIVAARPSMGKTTFAMNLCENAAMLQDKPVLIFSLEMPGEQIMMRMLASL
                     SRVDQTRIRTGQLDDEDWARISGTMGILLEKRNMYIDDSSGLTPTEVRSRARRIFREH
                     GGLSLIMIDYLQLMRVPSLSDNRTLEIAEISRSLKALAKELQVPVVALSQLNRSLEQR
                     ADKRPVNSDLRESGSIEQDADLIMFIYRDEVYHENSDLKGIAEIIIGKQRNGPIGTVR
                     LTFNGQWSRFDNYAGPQYDDE"
     gene            25856..26935
                     /gene="alr"
                     /locus_tag="OPV72_000842"
     CDS             25856..26935
                     /gene="alr"
                     /locus_tag="OPV72_000842"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HCR9913214.1"
                     /translation="MQAATVVINRRALRHNLQRLRELAPASKLVAVVKANAYGHGLLE
                     TARTLPDADAFGVARLEEALRLRAGGITQPILLLEGFFDAADLPTISAQCLHTAVHNQ
                     EQLAALEAVELAEPVTVWMKLDTGMHRLGVRPEEAEAFYQRLTHCKNVRQPVNIVSHF
                     ARADEPECGATEHQLDIFNAFCQGKPGQRSIAASGGILLWPQSHFDWARPGIILYGVS
                     PLEHKPWGPDFGFQPVMSLTSSLIAVRDHKAGEPVGYGGTWVSERDTRLGVVAMGYGD
                     GYPRAAPSGTPVLVNGREVPIVGRVAMDMICVDLGPNAQDNAGDPVVLWGEGLPVERI
                     AEMTKVSAYELITRLTSRVAMKYID"
     gene            27121..28314
                     /gene="tyrB"
                     /locus_tag="OPV72_000843"
     CDS             27121..28314
                     /gene="tyrB"
                     /locus_tag="OPV72_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic amino acid transaminase"
                     /protein_id="HCR9913215.1"
                     /translation="MFQKVDAYAGDPILSLMERFKDDSRHDKVNLSIGLYYNEDGIIP
                     QLKTVAEAEARLNAQPHGASLYLPMEGLNTYRHTIAPLLFGADHPVLQQQRVATIQTL
                     GGSGALKVGADFLKRYFPDAGVWVSDPTWENHIAIFAGAGFEVSTYPWYDDATNGIRF
                     NDLLATLNTLPARSIVLLHPCCHNPTGADLTPSQWDAVIEIVKARDLIPFLDIAYQGF
                     GAGMDEDAYAIRAIASAGLPALVSNSFSKIFSLYGECVGGLSVVCEDAEIAARVLGQL
                     KATVRRIYSSPPCFGAQVVATVLGDEALKASWLAEVDAMRTRIISMRQTLVKELKAEM
                     PDRNFDYLLQQRGMFSYTGLSAEQVDRLRDEFGVYLIASGRMCVAGLNASNVHRVAKA
                     FAAVM"
     gene            28501..29214
                     /gene="aphA"
                     /locus_tag="OPV72_000844"
     CDS             28501..29214
                     /gene="aphA"
                     /locus_tag="OPV72_000844"
                     /EC_number="3.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid phosphatase AphA"
                     /protein_id="HCR9913216.1"
                     /translation="MKKITLALSAVCLLFTLNHSANALVSSPSTLNPGTNVAKLAEQA
                     PVHWVSVAQIENSLTGRPPMAVGFDIDDTVLFSSPGFWRGKKTYSPDSDDYLKNPAFW
                     EKMNNGWDEFSIPKEVARQLIDMHVRRGDSIYFVTGRSQTKTETVSKTLADNFHIPAA
                     NMNPVIFAGDKPGQNTKVQWLQEKNMRIFYGDSDNDITAARDCGIRGIRILRAANSTY
                     KPLPQAGAFGEEVIVNSEY"
     gene            29343..29759
                     /locus_tag="OPV72_000845"
     CDS             29343..29759
                     /locus_tag="OPV72_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbQ family protein"
                     /protein_id="HCR9913217.1"
                     /translation="MWYQRTITLSEKPRGFHLITDEITDKLSGLPPVETGLLHLLLLH
                     TSASLTLNENCDPTVRADMERHFLKTVPDNAAYEHDYEGADDMPSHIKSSVLGVSLLL
                     PVRQGRLQLGTWQGIWLGEHRIHGGPRKIIATLQGE"
     gene            29762..30118
                     /locus_tag="OPV72_000846"
     CDS             29762..30118
                     /locus_tag="OPV72_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HCR9913218.1"
                     /translation="MTISELLQYCMAKPGAEQSVHSDWKATQIKVEDVLFAMVKEVDG
                     RPAASLKTSPELAELLRQQHSDVRSSRHLNKAHWSTVYLDGSLPDSQLYYLVDASYQQ
                     AVNALSEDKRKQLPQS"
     gene            complement(30119..30457)
                     /locus_tag="OPV72_000847"
     CDS             complement(30119..30457)
                     /locus_tag="OPV72_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913219.1"
                     /translation="MASINEIRNLFTAARAEHPVASSAIAEFIQTYKQAREDSDDGIR
                     ESAAFIARALQEHARGWLDDDDMIILLEGQRDLARLRANNAQIALGSRIRSTVIHLID
                     IALALLVGAL"
     gene            complement(30444..30899)
                     /locus_tag="OPV72_000848"
     CDS             complement(30444..30899)
                     /locus_tag="OPV72_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913220.1"
                     /translation="MENTMKLPYAITLLLCLFLAACTLPDRFSAVAFQQLTLLQARST
                     RFLQDAARIPWQKETLLKDDRDIRQTFFQAERVARQGGDKHRLDNLALLKNHYLRLYA
                     RVMKCKQPLTYIQAERYQQQNNQVWKLAIQGECLHWGARCTQGEENGVY"
     gene            complement(31031..33856)
                     /gene="uvrA"
                     /locus_tag="OPV72_000849"
     CDS             complement(31031..33856)
                     /gene="uvrA"
                     /locus_tag="OPV72_000849"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HCR9913221.1"
                     /translation="MDKIEVRGARTHNLKNINLVIPRDKLIVVTGLSGSGKSSLAFDT
                     LYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTIT
                     EIHDYLRLLFARVGEPRCPDHDVPLAAQTVSQMVDNVLSQPEGKRLMLLAPIIKERKG
                     EHTKTLENLASQGYIRARIDGEVCDLSDPPKLELQKKHTIEVVIDRFKVRNDLSQRLA
                     ESFETALELSGGTAVVADMDDEKAEELLFSANFACPICGYSMRELEPRLFSFNNPAGA
                     CPTCDGLGVQQYFDPDRVIQNPDLSLAGGAIRGWDRRNFYYFQMLKSLAEHYKFDVDA
                     PWASLSANVHKVVLYGSGKENIEFKYMNDRGDTSVRRHPFEGVLHNMERRYKETESSA
                     VREELAKFISNRPCASCEGTRLNREARHVFVENTPLPAISDMSIGHAMDFFTNLKLSG
                     QRAKIAEKVLKEIGDRLKFLVNVGLNYLTLSRSAETLSGGEAQRIRLASQIGAGLVGV
                     MYVLDEPSIGLHQRDNERLLGTLIHLRNLGNTVIVVEHDEDAIRAADHVIDIGPGAGV
                     HGGEVVAEGPLEAIMAVPESLTGQYMSGKRKIEVPKQRVPANPEKVLKLTGARGNNLK
                     DVTLTLPVGLFTCITGVSGSGKSTLINDTLFPIAQRQLNGATIAEPAPYRDIQGLEHF
                     DKVIDIDQSPIGRTPRSNPATYTGVFTPVRELFAGVPESRSRGYTPGRFSFNVRGGRC
                     EACQGDGVIKVEMHFLPDIYVPCDQCKGKRYNRETLEIKYKGKTIHEVLDMTIEEARE
                     FFDAVPALARKLQTLMDVGLTYIRLGQSATTLSGGEAQRVKLARELSKRGTGQTLYIL
                     DEPTTGLHFADIQQLLDVLHQLRDQGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGE
                     ILVAGTPETVAECEASHTARFLKPMLK"
     gene            34104..34634
                     /gene="ssb1"
                     /locus_tag="OPV72_000850"
     CDS             34104..34634
                     /gene="ssb1"
                     /locus_tag="OPV72_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SSB1"
                     /protein_id="HCR9913222.1"
                     /translation="MASRGVNKVILVGNLGQDPEVRYMPSGGAVANLTLATSESWRDK
                     QTGEMKEQTEWHRVVMFGKLAEVAGEYLRKGSQVYIEGQLRTRKWTDQSGQERYTTEI
                     NVPQIGGVMQMLGGRQGGGAPAGGQQQGGWGQPQQPQQPQGGNQFSGGAQSRPQQSAP
                     APSNEPPMDFDDDIPF"
BASE COUNT         7888 a         9042 c         9776 g         8183 t
ORIGIN      
        1 ggttgtgtat actcggtagc gcccgaaatt cttttgggta aatctccatt cattcaatga
       61 agggaaatta tgatgaaaaa agtactgtat ggcatttttg ccataaccgc gcttgcggcg
      121 acatctgtct cggcagcccc cgttcaggtg ggtgaagcgg cagggtcggc agcgacgtcg
      181 gtatcggcgg gaagctcctc cgctaccagc gttagcaccg taagttcggc ggtgggcgtc
      241 gcgttagcgg caaccggcgg cggcgatggt tccaataccg gaaccacgac caccacgacc
      301 accagtaccc agtagtatcg gtacgtttaa ccataaccac actccggtgt ggttattttg
      361 cccctctgga gaagcgtcgt gaagcgactc gcacttatcc tgatttgcct gctattacag
      421 gcgtgttcgg ccaccaccaa aggcctgggc gattcactgt gggacagttt gttcggtacg
      481 ccaggcgtac agctaacgga tgacgatatt caaaacatgc cttatgccag ccagtacatg
      541 cagcttaacg gcggtcctca actgtttgtg gtgctcgctt tctcggaaaa cgggcagcag
      601 aaatgggtga cgcaggatgg cgcgacgatc gtgacgcagc atggccgtct ggtcaaaacg
      661 ctgctcggcg gcgacaacct gatcgatgtg aataatctgg cgaccgaccc gctggcgaaa
      721 ccaggacaga ttatcgatgg cgcgacctgg actcgcaccc tgggctggac cgaacatcgc
      781 caggtgcgtt acgccaccgc ccgttccgtt tttacatggc gagggaccga tagagtgaac
      841 gtcggcagtg aggaaaccgc cgtgcgggtg ttagatgaag aagtgacgac cgatcaaacg
      901 cgctggcgta atcgctactg ggttgatagc gaaggccaaa ttcgccagac ggaacagtat
      961 ctgggcgcga attactttcc ggtgaaaacc acgctgatta aggcggcaaa atcatgatga
     1021 aaaggacgat aagcgcgctg gcgctggcct ttgtcgcgtc atccgccttt gccagcggca
     1081 ctgttaccgt ttttacccag ggtaatagcg agcctaaaac gctgacagac gctgagcgtc
     1141 tgctcgattt agtcggacag ccgcgcctgg caacgagctg gtggcctgcg gcggtgatag
     1201 gcgaagaaca ggcgaccgtg acggcgcgtc agcagcagca ggaacttctc gggcgactgg
     1261 cggcgctcag cgctgaggaa gatggcgatg cggcggcgat aaacacacta cgccgacaga
     1321 ttcaggcggt gaaggtgacg ggcagacaat tcgtgaatct tgatcctgac gtggtgcggg
     1381 tgagcgaacg aggtaacccg ccgctgcaag gtcactacac gctctgggtc gggccgcaac
     1441 ccacgcaggt gacgctcttt ggcttgatta gccagccggg cagccagccg ttcgtccctg
     1501 ggcgggacgt cgccagttat cttgaggggc agcgcttact cagcggcgcg gatcgtagct
     1561 atgcctgggt ggtttaccct gatggacgca gccaaaaagc gccggtggct tactggaata
     1621 aacgtcatat cgagccgatg cccggcagca tcatttttgt cggttttgcc gattcccttt
     1681 ggcgcggcac gccggaggcg ataaatgccg acattcttca taccctgacg cagcggatac
     1741 cggaataatg aaaaaaacac atctgctcag cgtgctggcg ctgggtatta gcgcggcctg
     1801 ccatgccgaa acatatccag cccctgttgg gccttcacaa tctgactttg gcggcgtggg
     1861 cctgctgcaa acgccgacag cgcgtatggc gcgtgaaggg gagatgagcc tgaactatcg
     1921 cgataacgat cagtaccgct actactcggc ttcggttcag cttttcccgt ggctggaaac
     1981 cacgttgcgc tataccgatg tccgtacgaa aaagtacagc agcgtggaat cattctccgg
     2041 cgaccagact tacaaagata aagcgtttga tgtgaaactg cggttgtggg aagagagtta
     2101 ctggatgccg caggtggcgg ttggcgcgcg cgatatcggc gggacggggc tgtttgatgc
     2161 ggaatatatt gtagcgagta aggcttgggg gccatttgat ttttcattag gtctcggctg
     2221 gggctatctt ggcaccagcg gcaatgtgtc taatcctttc tgttcgtata gtgataaatt
     2281 ctgttcgcgt gataacagct ataaagaggc cggttccgtc gacggtagcg atatgtttca
     2341 cggcccggct tcgctgtttg gcggcgtgga ataccagacc ccgtggcaac cgctacgcct
     2401 gaagctggag tatgaaggca ataactatca gcaggatttt gcggggaaac tggaacagaa
     2461 gagcaagttt aacgtcggcg ccatttactg cgtcaccgat tgggccgacg ttaacctcag
     2521 ctacgagcgc ggcaacacct ttatgtttgg cgttacgctg cgcaccaatt tcaacgattt
     2581 acgtcccgcg tatcatgaca attcacgccc gcaataccga ccacagccgc aggatgccat
     2641 cctgcaacat tcggtagtgg ctaatcaatt aacgttattg aaatataatg ccggtctggc
     2701 ggacccgaaa atccaggtca aaggcgatac gctatacgtt accggtgaac aggtgaagta
     2761 ccgcgactcc cgtgagggga tcgtgcgcgc taaccggatc gtcatgaacg atctgccgga
     2821 ggggatccgc acgatccgcg tgacggaaaa ccgccttaat ctgccgcagg tcaccactga
     2881 aaccgatgtc gccagcctga aacgccatct ggaaggcgaa ccgctgggac atgaaactcc
     2941 gctggcgcaa aaacgcgtgg agccgatcgt gccagagagt actgaacagg gttggtatat
     3001 cgacaagtcg cgcattgatt ttcatcttga tcccgtgctg aatcagtcgg taggcggccc
     3061 ggaaaacttc tatatgtatc agttgggcgt aatgggaact gcggatctgt gggtcacgga
     3121 tcatctgctc accacgggca gcgtgtttgc caatatcgcc aacaactacg acaaatttaa
     3181 ctacaccaat ccaccgaagg actcgcatct gccgcgggtg cgtacgcatg tccgtgagta
     3241 tgtgcagaat gatgtttatg tgaataacct acaggccaac tacttccagt attttggcaa
     3301 tggtttctat gggcaggtct atggcggtta tctggagacc atgtttggcg gtgccggggc
     3361 ggaagtcctg tatcgcccgg tagacagcaa ttgggcgttt ggtctggatg ccaactacgt
     3421 gaaacagcgt gactggcgta gcgcgcagga tatgatgaag tttaccgatt acagcgtgaa
     3481 gaccggacat ttgaccgcat actggacgcc gtcgttcgcc caggatgtgc tggtgaaagc
     3541 cagcgttggt cagtatctgg cgggcgataa aggcggtacg ctggagatcg ccaaacgctt
     3601 cgatagcggc gtcgttgtcg gcggttacgc gacgattacc gatgcgtcgc cggatgaata
     3661 tggggaaggg gattttacca aaggcgtata tgtttccgta ccgctggatc tcttctcgtc
     3721 cggcccaacc cgaagtcgtg cggcaattgg ctggacgccg ctgacgcgtg acggtggtca
     3781 acagcttggc cgtaagtttg gcctgtatga tatgaccagt gacaggagcg taaatttccg
     3841 ttaatactca ggccggataa ggcgttcacg gcgctatccg gcaaattacc ttattgaaca
     3901 aaatataaac acaaataaaa aatatagatg cccgtcacat ttgtgcgtta tacagaaacc
     3961 tcgccgcaga gaaagagggg gctgttatga tgccattatc gcgctcacgt cttgagttta
     4021 tcgccacgat tttacaaaac gtactaaatt tggggctgct taccctcggt ctgatcctgg
     4081 tcgtttttct cggtaaagag acggtgcatc tggcggacgc attattcgcg cctgagcaag
     4141 ccagcaaata tgaactggtg gaagggctgg tgatctactt tctttatttc gaatttattg
     4201 cgctgattgt gaagtacttt aagtctggcc ttcactttcc gctgcgctat ttcgtgtaca
     4261 ttgggatcac ggcgattgtg cgtctgatca ttgtcgatca taaaacgcca atggatgtat
     4321 tactctattc ggcggcgatc ctcctgttgg ttatcacgtt gtggttatgt aattcgaacc
     4381 gactacggcg agaataggcg tcgccacacc gtaacggacg tatggcgtgg caataaatta
     4441 gccgctgtct ataacgcata aaaaaagcgc tccgaagagc gccaaaatac gaccataagt
     4501 ggggataaca taacttgagg gcagtggcat tgcccgttgc cgggcaggta cttcgataaa
     4561 acttaacctt tcacaccccc tgccgtcagg ccgttgacca gccaacgttg cgccaacagg
     4621 aacaccaggg tgataggaat agctgaaagg acggcggcgg cggcaaagtc gccccacaaa
     4681 tagttttgcg ggttgagata ttgctgcata cccacggcca gcgtatagct gtccacatcg
     4741 cgcagtaaca acgaggcgac cggaacttcg gtaatcgccg cgatgaacga cagaataaac
     4801 accaccgcca gaatcggtac ggaaagcggc agcagcacca gacgaaatgc ctgccacggg
     4861 gttgcgccat ccagcgcggc ggcctcttcc agcgagctgt cgatagtttc gaagtagcct
     4921 ttaattgtcc agacgtgcag cgcgatgccg ccaagatagg cgaagatcac gccgccatgc
     4981 gtattcagac cgataaatgg aatgtattgt cccaggcggt caaataacgc atacagcgcc
     5041 accagagaca aaaccgccgg aaacatctgg aaaatcagca tccctttgag cagtgttgct
     5101 ttacctggaa aacgcattcg tgcgaaagcg taggcgcagg tggtggagag cgccacgatg
     5161 ccgatggcgg taataccggc gattttcacc gagttccaca gccacagcag gaccgggaag
     5221 ggaggcggcg ttacccgacc atccgcatgt tccacgctga aacccagcgc cagccgccag
     5281 tgttcccagg agattttatc cgggatcagg cttccggtgg cgaagttccc ttcacgtagc
     5341 gagatagcga tgaccatcag cagcgggaac ataatcgccg cgatgaaaat cagcagcccc
     5401 aggtgcgtga tgaagagacg cagtttctga gatttgggtt ggaccatagc cattgttatt
     5461 atctccctta atcaaacttc atacgcgtgg ctttcaggtt cactattgcc agcgcgccta
     5521 ccagcaggaa gatcagcgtg gcaatggccg ccgccagacc gaagtcctga ccgccgccgc
     5581 cttcaaaggc gatacggtag gtgtagctga cgagcagatc ggtataaccg gcaggcgtgg
     5641 tggtgccgag acggtctggc ccgccgttgg tcaataactg aatcaggaca aagttattaa
     5701 agttaaaggc gaagctggcg atcatcagcg gcgttagcgg cttaatcagc agcggtaagg
     5761 tgattttaaa gaaattctga aatggaccag cgccgtccat tgcggaggct tcgtacaggt
     5821 catccggaat cgctttcagc agtcccatgc acaggatcat catgtaggga tagcccagcc
     5881 aggtattcac gataatcacc attgcccgcg cggtgttggg gtcgctgaac caggcaggtt
     5941 taatgccaaa cagcgcgctc agcatcatat tgatttcgcc aaagctttgg ttgaataacc
     6001 ctttgaaaat caaaattgaa ataaacgacg gtacggcgta gggcagaatc agcaggacgc
     6061 ggtagatagc tttacctttc agcgcttccc actgtacgag gcaggccaat accatcccaa
     6121 ccgccacggt taacaccaca gtgaggaccg aaaagaccac ggtccagacg aagatagcga
     6181 aaaaaggctt ctggatccct tcgtcggtaa agacgcgcgt aaagtttttc gcgccgatag
     6241 taacggtata accaggactg agtttttcat caccccagct tccgtcggcg ttgatcgact
     6301 gataataacc gctatcgttg tttggccggt attttacgcc gctctggtta ttggtaagca
     6361 ggccgtcatc agccagtgtg tacagcggac gggtaccgga aaactgacgc agcgagctca
     6421 taaccacttt actttcatcc ggcaggacgg cggttatctg gttcagcgcc agacggttct
     6481 gggtgattat ccgcagattg gcgcgttcgc cgcccggcag ggcatcggtc tctttcagct
     6541 gtaatttttg ttcgccgccg aaggaaaatg cgccagacag gtaatgtttg cccgtttctc
     6601 cgtcggtgag ggccagttgc cactcgtcgc cggccgggta aagaccgaag ttataggttt
     6661 ttcccgcctg ataagaacgg tccatcagca cttgctgggc gcgttcaaag gtgagctggt
     6721 tggtgctgct gtagttagta aaggcgatgg cgatggtgca caccagcggg aatagcacaa
     6781 acagccccat gccggcgagg ccagggtaaa cgtagcgcca ggcataggtt ttacgatttg
     6841 cgaaaatata caggccagca gagcttaaaa tcagcgtcat gatggcgaac agatactccc
     6901 cttgtacgta cattaaaact acaaggtaac ccaccagcag gcccagcaga ccaattactg
     6961 accatttaag ctggtcgctt tgccaccagt gtttcttttt aatgacatcc atgggggttt
     7021 tcctctacag cgttgaaact tcctggccgg agatgtgcct gatggcgctg cgcttatcag
     7081 gcctacggtg tgttgtaggc cggataaggc atttatgccg ccatccggca caggctcgcg
     7141 gcattacttg gtgatacggc tttgtgcatc tttcagcgcg gcatccacgg tttgacggcc
     7201 gctggcggcg ttaatcacag ccgtacgtac cgcataccag aaggcggaca tctgcggaat
     7261 attcggcatg atctcgcctt tctgggcgtt atccatggtg gcggcgatac gggggtcttt
     7321 cgctaactgc tcctggaaag atttcagcgc cacggcgccc agcggtttgt ctttgttcac
     7381 cgcctccaga ccctgatcgg tcagcaggta gttttcgagg aactctttcg ccagctcttt
     7441 attcgggctg gcagcgttaa tccccgcgct cagcacgccg acgaacggtt tcgagggttt
     7501 acctttgaag gtcggcagca gggtgacacc gtagttgact ttgctcttgt cgatgttcga
     7561 ccatgcccac ggaccgttga tggtcattgc cgtttcgcct ttattgaagg ctgcttcggc
     7621 gatggagtaa tcggtatcgg cgctcatatt tttgttcttg atcatatcga tcaggaaagt
     7681 cagacctgct ttcgcgccgg cgttgtcgac gccaacgtct ttcacgtcat acttgccgtt
     7741 ttcaaatttg aacgcgtaac cgccgtcagc ggcgatcaaa ggccaggtga aatacggctc
     7801 ttgcaggttg aacattatcg ccgacttccc tttcgctttt agctctttat ccagcgccgg
     7861 gatctcttcc caggttttcg gcgggttcgg gacgaggtct ttgttataaa tcagggagag
     7921 ggcttcaacg gcgatggggt aggcgatcag cttgccgtta taacgtaccg catcccaggt
     7981 aaacggatag agtttgtcct gaaacgcttt atccggagta acctccgcca gcagaccaga
     8041 ctgcgcgtag ccgccaaaac ggtcgtgcgc ccagaagata atgtcaggac cgtcgccggt
     8101 ggcagccacc tgcgggaatt tctcttccag cttatccggg tgctcaacgg tcactttaat
     8161 gccggtgtct tgctcaaatt ttttaccgac ctcggccaga ccgttatagc ccttgtcgcc
     8221 gttgatccag ataaccagtt taccttcttc aattttggcg agagccgggg cggaaatcat
     8281 catcgtcgta agtgcggata atgcgaggat gcctacgcca gttttaatct tcatatctcc
     8341 catccttttt ggtgatgtac acagaggtgg tttaacggtc tctagtttct ttatacgaca
     8401 acctctttcc atcctcccta cccctacgcc ccaccccggc tttatgtgat ctgtgttgca
     8461 taaatgtgag taatgcgtgc tggcgcacac aaaaacacgc cgatttttgc gggcggcatc
     8521 acgaaattcc ttttctgtcc gcgcccgtgg tctcaggcgt tgtgtcctca tcctcccgcc
     8581 tcctccccca taaaaaagcc ggggggtgga ggatttaccc cagtcaggga tcgcgcatag
     8641 tcaggccatc atgaatgttg ctgtcaatga caggttgtaa cgaagggaga agggcatggc
     8701 gagcgtacag ctacgaaatg taacgaaagc ctggggtgac gtggtggtat cgaaagatat
     8761 taacctcgat atccatgacg gggagttcgt ggtgtttgtc ggaccgtcag gctgtggtaa
     8821 atcgaccttg ctgcgtatga tcgccgggct tgaaactatc accagtggcg acctgtttat
     8881 cggggaaacc cgtatgaatg atattccgcc tgccgagcgc ggcgtgggca tggtattcca
     8941 gtcttatgcg ctctatcccc atctctccgt tgcagaaaac atgtctttcg gcctcaagct
     9001 ggcgggcgcc aaaaaagagg taatgaatca acgcgtcaat caggtggcgg aagtactgca
     9061 actggcgcat ctgctggaac gtaagccaaa agcgctttcc ggcggtcagc gtcagcgcgt
     9121 agcgattggc cgcacgctgg tggcggagcc gcgtgtgttt ttgctggatg aaccgctctc
     9181 taacctggat gccgcgctac gcgtgcagat gcgcattgaa atttctcgcc tgcataaacg
     9241 tctgggccgc acgatgattt acgtcaccca cgatcaggtc gaggcgatga cgctggccga
     9301 caaaatcgtg gtgctggacg ctggtcgcgt cgcgcaggtc ggtaagccgc tggagctgta
     9361 ccactatccg gcggaccgct ttgtcgcggg ctttatcggc tcgccgaaga tgaacttcct
     9421 gccggtgaaa gtgaccgcca ccgcaattga acaagtccag gtcgaactgc cgaatcgcca
     9481 gcaaatctgg ctgccggtcg aaagtcgcgg cgtgcaggtc ggcgccaata tgtctttagg
     9541 cattcggccg gaacacctgc tgccgagcga tatcgccgat gtcaccctgg aaggtgaagt
     9601 ccaggtggtc gagcagttag ggcacgaaac acaaattcat atccagatcc ccgccatccg
     9661 tcaaaacctg gtttatcgcc agaatgacgt ggtgctggta gaagagggcg ccacattcgc
     9721 tatcggcctg ccgccagagc gctgtcatct gttccgcgag gatggcagcg catgtcgtcg
     9781 tctgcatcaa gagccgggtg tttaaggcct ccataaaaaa acgaaacgca aaaccattcg
     9841 cagttttaga aggtggcagc gtttaaagaa aagcaatgat ctcaggagta tagaatgatg
     9901 attactctgc gcaaactccc tctggcggtt gctgtcgcag cgggcgtaat gtccgctcag
     9961 gcaatggctg tcgatttcca cggttacgcc cgttccggta ttggctggac gggaagcggc
    10021 ggcgaacaac aatgtttcca ggtgaccggt gcacaaagta aataccgtct cggtaacgaa
    10081 tgtgaaacct atgcggaact gaaactgggc caggaagtgt ggaaagaggg cgataagagc
    10141 ttctatttcg acaccaacgt cgcctattcg gttaaccagc agaacgactg ggaatcgacc
    10201 gatcccgcct tccgcgaagc gaacgtgcag ggtaaaaacc tgattgaatg gctgccgggc
    10261 tctaccatct gggccggtaa gcgcttctat cagcgtcatg acgtacacat gatcgacttc
    10321 tactactggg atatttcagg tcctggcgca ggtatcgaaa atatcgatct gggcttcggt
    10381 aagctttcgc tggcggcgac ccggtctact gaagcgggcg gctcttacac cttcagcagc
    10441 cagaatattt atgatgaagt aaaagatacc gctaacgacg tctttgacgt acgtctggct
    10501 ggtctgcaaa cgaacccgga cggcgtactg gagttgggcg ttgactacgg tcgcgccaat
    10561 acgaccgatg gttataagct ggctgatggg gcatcgaaag acggctggat gttcaccgcc
    10621 gaacacacgc aaagcatgtt gaaaggctat aacaagtttg tcgtgcaata tgccaccgat
    10681 gccatgacca cgcagggtaa aggccaggcg cgcggttccg acggttcttc atctttcact
    10741 gaagaattgc ctgatggaac caaaattaat tatgccaata aggtcatcaa taataatggc
    10801 gatatgtggc gtattttgga tcatggcgcc atctcgcttg gtgataaatg ggatttgatg
    10861 tacgtcggta tgtaccagaa tatcgattgg gataataacc tgggtactga gtggtggacc
    10921 gtgggcgtac gtccaatgta caagtggacg ccaatcatga gtaccctgct ggaagtcggc
    10981 tacgacaacg tgaaatctca gcagaccggc gatcgtaaca atcaatataa aatcaccctg
    11041 gcgcaacagt ggcaggcggg cgacagcatc tggtcgcgtc cggctatccg tattttcgcc
    11101 acctacgcga aatgggatga gaaatggggc tatatcaaag acggcgataa catttcccgt
    11161 tatgccgcag cgactaactc cggcatttcc accaacagcc gtggcgatag cgatgagtgg
    11221 accttcggcg cccagatgga aatctggtgg taatacgatg gtcatctgac gtaacgaggg
    11281 gcgcaagccc ctctgaaaca tcaggtctga tgatgcttgt aagccgaata aggcgccagc
    11341 cgccattcgg cgatatgttt gggttggcgc gctattgcct ggctaccgct gaacccgcct
    11401 tattgaggtg agaataatga aaatgaagaa aagtctcgtc gccctctgtt taaccgcagg
    11461 gctgttcgcc agcgtgccgg gtatcagcct ggcggaagtg aactatgtac cgcaaaatac
    11521 cagtgccgcg cccgctattc ctgctgctgc gctacagcaa ttaacctgga cgcctgtaga
    11581 tcagtcaaaa acgcagtcta cccaactggc gacgggcggc cagcgccttg acgtcgccgg
    11641 cattaccggc ccggtcgccg cttatagcgt tccggcgaat atcggcgagc tgacattaac
    11701 tctgaccagc gaggtcaata agcaagccag cgtttttgcg ccaaacgtgt tgattcttga
    11761 ccaaaatatg acgccttcgg cgttcttccc cagcagttac tttacttatc agcagccggg
    11821 cgtcatgagc gcagatcggc tggaaggcgt gatgcgcctg acgcctgcgt tggggcagca
    11881 gaaactctat gttctggtgt ttacgaccga aaaagatctt cagcaaacta ctacgctgct
    11941 cgatccggca aaagcctatg ccaaaggcgt cggtaactct atcccggata ttcccgatcc
    12001 agttgctcgc cataccactg atggcgtggt gaaactgaag gtgaaaacca acagtagctc
    12061 cagcgtattg gtcgggccgt tgtttggctc gtccggtacc gggccggtaa cggtaggcaa
    12121 taccgccgcg ccggtcgctg cgccagcgcc agtcgcgccg aagaaaagcg aaccgatgtt
    12181 gaacgatacg gaaagctact ttaataaagc gattaaggat gccgtagcga aaggcgacgt
    12241 cgataaagcg ctgaaactgc ttgatgaggc cgaacgtctg ggatcgacat ctgcccgttc
    12301 cacctttatc agcagtgtaa aaggcaaggg gtaattgttt ccccacagtg ctgattttgc
    12361 agcaactggt gcgtctcctg gcgcaccttt ttttgtcatt tcatgcgaat tgttattttt
    12421 ttgttgcgca acagatcact taattgtgat tgcgcccccc gtaatgtctt ttctgagata
    12481 caatgacttt aggttatgaa tcggagagta aggcatgtca caccctgcgt taacgcaact
    12541 gcgtgcgctg cgctattttg atgcgattcc tgcgcttgaa ccccatttgc tggactggct
    12601 gttgctggaa gattctgtga ctaaacgttt tgagcagcag ggaaagcggg taagcgtgac
    12661 gctgattcgg gaagcgtttg tcggccaaag tgaggtcgag gaagcatcag gtttactgcc
    12721 atccgagtcc cgctactggt tacgtgagat actgctttgc gctgacggcg agccctggct
    12781 tgccggacgt accgtggtac cggaatccac gctgtgcgga cctgaacagg tcttacaaca
    12841 tctgggtaaa accccgcttg gacgttatct atttacatca tcgacactga cccgcgattt
    12901 tattgaaatt ggacgcgatg caacgctgtg ggggcgccgc tctcgactgc ggttgagcgg
    12961 aaaaccgctg ttgcttaccg agcttttttt acctgcatcg ccgctgtact gagaggaaga
    13021 taaagatgga gtggagtctg acgcagagta agctgctggc gtttcaccgt ttgatgcgta
    13081 cagataagcc tattggcgcg ttgctgctgc tctggccgac gctttgggcg ctatgggtgg
    13141 cgacgccggg tatgcctcag ctgtggattt tggcagtttt tgtcgctggc gtgtggttaa
    13201 tgcgcgcggc gggctgcgtg gtgaatgatt atgccgatcg taaatttgac ggacatgtaa
    13261 aacgtacggt caaccgacct ttacccagcg gcgccgtgac agagaaagaa gcgcgcaacc
    13321 tgtttgtggt gctggtgctg ctggcgtttc tgttggtgct gacgctgaac gccatgacga
    13381 ttctgctttc cgtggcggcg ctggcgttgg cctgggttta tccctttatg aaacgctaca
    13441 cccacctgcc gcaggtcgtg ctgggggccg ctttcggctg gtcaatcccc atggcgttcg
    13501 ccgcggtgag cgaatccctg ccgttgagct gctggctgat gttcctcgcc aatattctct
    13561 gggcggtggc ttacgatacg caatatgcga tggtcgacag agatgatgat atcaagatag
    13621 gcattaaatc gactgcgatc ttgtttggtc gttatgacac attgattatc gggattctgc
    13681 agcttggcgt catggcgtta atggcgctga tcggctggtt gaatggtctg ggatggggat
    13741 attactgggc tgtgctggtg gcgggcgcgc tgtttgtcta ccagcaaaaa ctgattgcga
    13801 accgtgaacg tgaagcctgc tttaaagcct ttatgaacaa taactacgtt ggcctggtgc
    13861 tatttttagg gctggcgatg agttactggc acttctgatg tcatgccggg cgaacccggc
    13921 ctacaaagcc aaaattttca atacgtcata tcagttgccc gatgagcttg cactatcggg
    13981 catttcaggc actggcttac tcgccctgcg tcgcgctttc aatcgtcaga cggacatcag
    14041 aggtaattag atcggcaagc atctgatata tcttcatcgt ttctgccggt tcggcatcgc
    14101 ccgtatcact gatataaccc tcatcccgta gcgtcaacac gagtgaactg aacaccgctt
    14161 tgtcgaaaaa ctccggcgcg ttaataccgt gcaggacaga cagacgttgc gccacggtac
    14221 ggctttcttt ctccagcgta ctgcggttga tggacggatt ggcgctcaat agccagaacg
    14281 taatggcata acgctgtagc gtttcacgcg cgcctgccgc cagcagttgc agcgtacggg
    14341 aatgcgtcgg gttgatatgc agttcatcat cctgcagggt aattagcccc tgacgctgca
    14401 tttcactggc cagcgcgtcg atgaccgagg ctaactcctc gcgctcccag cgcaggaaca
    14461 gctccgcttt taacatcgga tagagcgctt caacatgctg ctgcaacgca tcacgcgaaa
    14521 tgcgacgatg ctgggtgata atcgccgcca tcagcgaagg cataatcaac atatgcgcga
    14581 tattgttacg ataataggtc atcaacaccg cctgctcgcg cggcaggatg atgatatcgc
    14641 caatggtgtc tttctcgacc tcaaacttat tcatctgcag cgcgtgagcg atgagctcgc
    14701 cagcgctggc ggcaggaacc gttgagtctg tggaataagg gacattgcgc atcagatcga
    14761 gatagcagtc aagctgctcg gtgagctgct cgcgggtgag cgagcgctga cgcgacgcta
    14821 acagcgcggt acaacacagg ttcatcgcgt ttgccgcgcc agcgttgtta atacgcacca
    14881 tcagatcggc ggcaatacta tttaccgtcg gcgtcagcca ggctgggcgt atggcctcta
    14941 tagggtcgat agattcgcgc cactctggca catgctggtt caggtacgtc atgagcggca
    15001 tcggttcgcc aaagttaacg tagccctgac ccagattgcg cagcttgctc aagcctttca
    15061 gcatctgcgg cagactctct ttctcttttg tcgcgccgcg cagctctttc gcataggtgc
    15121 ccacttccat gacgtgctca tagccaatgt agatcggtac gagggtaatt gggcgggtac
    15181 cgccgcgtag catcgcctgg atagtcatcg acagggtgcc ggttttcgga tctaacaaac
    15241 gtccggtacg cgaacgtcct ccttcgacaa aatactcaac cgagtaaccg cggctgaaca
    15301 gctcgcccag gtattcgcga aagacggtgg aatagagttt attcccctta aaggtgcgac
    15361 gaataaagaa cgcgcccaga cgacggaaaa ttgggccagc gggccagaaa ttaaggttaa
    15421 taccggcggc aatgtgcggc ggaaccagcc cctgatggta cagcacataa gaaaggagca
    15481 agtagtccat atggctgcgg tgacagggta catagacgat ttcatgcccg tcgtgcgcca
    15541 gttggcgtac gcgctcggcg ttatgcacgt taatcccctg gtaaagtcgg ttccaggtaa
    15601 accccaaaat cctgtcggtc aaacgaatca tctcgtaaga gaagttcgcc gcgatctctt
    15661 ccatcagcgc aatggcgttt tgctgcgctt tttcatgaga gattttctta ctgcgcgctt
    15721 cgtcttctac cgcgcgggcg atcgctttcg aggccagcag tttgttaaac agatcctgac
    15781 gggcgggcag gcgtgggcca accgccgcca ggcgctggcg agcaaagtgc atacgcgcca
    15841 cgcgagccag cttctgcgcg atgattttat cggtgccgtg ttcatcagcc atgcgacgca
    15901 atgagacgga cggcgagaat cggacaaagc tatcgcggcc cagccaggag atggcaaaga
    15961 atttctgtac gccgttcagc atacgtaaag gcgggttctc ttctcctttt tcacgacccg
    16021 gcgcgcggcc aaacatcacg gaaacgggca ccatctgcac gtccaaagct ggattactcc
    16081 gatgcagatc gagataatcg tgaaaaagtt tcaccgactc ttcttttggc gtgtaatagg
    16141 taaagacacg cggtccgccg tgaataaata catagcgtgg caacagcgcg ccgtcgatct
    16201 ccagcggctc cagcggatcc gggagatcgt gcgccagaca ttgcgcccgc agcgtcagta
    16261 agtccgcttt tgagttgtat ggcaagacat acataatggg gcgagaagta tcgagcccca
    16321 attcctgggc gggttccgcc ggaatagact tgctttttac cagtatgctt aatggtaaat
    16381 tcagtaattt gtagtaaatt cgtggccagc cggacataaa cgatgtaaag cctctggtta
    16441 ataatgcaaa tgcggtgcaa ggatatcaga aagtttagcg aatttctgtt gtatcccgtc
    16501 atacttcgcg ctgcgttacg gcagtccgaa tcgtgcaggg caaccgtata atgtcattga
    16561 cgttaataat gtaaaaaggt tcttttgatg gccaataata ccactggatt caccagaatt
    16621 atcaaagcgg caggatattc ctggaaagga tttcgcgccg catggactca cgaagcggcg
    16681 tttcgccagg aaagcctcgc ggtattgctg ggcgtcatca tcgcctgctg gctggatgtg
    16741 gatgcgatta cccgtgtgtt attgataggt tccgttttac ttatcatgat tgttgaaatc
    16801 ctcaacagcg ctattgaagc ggtcgttgac cgcatcggtt ctgaatacca tgagctttcc
    16861 ggccgtgcga aagatatggg atcggctgcg gtgctactgt ctattttcgt tgccctgatg
    16921 acctggggca tcctgttatg gtcacatttt cgataaaggt tccaaatttt ataaatctct
    16981 tgttttttgc gccgtttgtg gttccaaaat cacctttaac tgtatatact cacagcatga
    17041 ctgtatatac acccaggggg cggaatgaaa gcgttaacgg ccaggcaaca agaggtgttt
    17101 gatctcatcc gggatcacat cagccagaca ggtatgccac cgacgcgtgc ggaaatcgcg
    17161 cagcgtttgg ggttccgttc cccaaacgct gcggaagaac accttaaggc gctggcgcgc
    17221 aaaggggtgc ttgaaatcgt ttccggcgca tcgcgaggta tccgtctgtt acaggaagaa
    17281 gaggacggat taccgcttgt cgggcgtgtc gcggcgggtg aaccgcttct ggcgcagcag
    17341 catattgaag gccattacca ggtcgatcct tcactgttca aacccagcgc cgatttcctg
    17401 ctgcgcgtga gcggtatgtc gatgaaagac atcggtatta tggatgggga tttgctggcg
    17461 gtacataaaa cgcaggacgt ccgtaatggc caggtggttg tcgctcgcat tgatgatgaa
    17521 gtgacagtaa aacggctgaa aaagcagggc aataaagtgg aactgctgcc ggaaaacagc
    17581 gagtttacac cgatagtggt ggatctgcgc gaacaaagct ttacgattga agggctggcg
    17641 gtaggcgtca ttcgcaacgg ggaatggttg taatctcttt ttaatctcct tgtaagccgc
    17701 catccggcaa tcgtgtagcc tgatggcgct gcgcttatca ggcctacggg aatgcagttc
    17761 ctgagatgat taatttgtag gccggataag gcgttacgtc gccatccggc aatgcgctcg
    17821 tttcgtttaa ctccttgtca ggcttttctc catgccgctt tttacctcct ctgataaagc
    17881 tctctggcgt cttgcgttgc cgatgatttt ttctaacatc accgtcccct tactggggct
    17941 ggtcgatacg gcggtgattg gtcatctgga cagccctgtt ttcctgggcg gcgtggcggt
    18001 gggcgcgact gccaccagct ttcttttcat gctgctgcta tttctacgta tgagcaccac
    18061 cggcctaacg gcgcaggcat ttggcgccaa aaatccgcag gcgttagccc gggcgctcat
    18121 tcaaccgtta ttgctggcgc tgggcgcagg cgtgatgatt gtgctatttc gcacgccgct
    18181 tatcgagctg gctttacata ttgtcggcgg gaacgacgct gtcctggtgc aggcgagacg
    18241 cttccttgaa attcgttggc taagcgctcc cgcgtcactg gcgaatctgg tgctgctcgg
    18301 ttggctgtta ggcgttcagt atgcgcgggc gccggttatc ttgttggtcg tgggcaatat
    18361 cctcaaaatc gcgctcgacc tgtggctggt gatggggctt catatgaacg tgcagggtgc
    18421 cgccctggcg acggtcatcg cagaatatgt cacgttactg atcggcctca tgatggtacg
    18481 taaagttctc catctccgcg gtgtgtcgct ggatatgcta aaacaggcct ggcgcggcaa
    18541 cgtgcgccgc cttttggcgc tcaatcgcga tatcatgctg cgctcattgc tccttcagct
    18601 ttgttttggc gcaatcacgg tgtcaggcgc gcggctgggc agcgatatta tcgcggtaaa
    18661 tgcagtcctg atgaccttac tcacctttac ggcctatgcg ctggacggtt ttgcttatgc
    18721 ggtggaggcg cactccggtc aggcttacgg cgcgcgtgac ggtagcaagc tactggacgt
    18781 ctggcgagcg gcgtgtcgtc agtcaggaat tgtggccttg ttgttttcca cggtctatgc
    18841 cctggcaggc gaacatattg tcgcgttact aacctcattg ccgcaaatac agctactggc
    18901 ggatcggtat cttatctggc aggtggtatt accgctggtg ggcgtatggt gctatctgct
    18961 cgacggtatg tttattggcg cgacgcgcgc tgccgaaatg cgcaatagca tggctgtcgc
    19021 cgcgggagga ttcgcgctga cgctcttcgc cctgccggta ttaggaaatc atggtttatg
    19081 gctggcatta accgtatttc tggcgctacg cggtctgtcg ttgagcctta tctggcgtcg
    19141 tcactggcgc gagggtacat ggtttgccag atcgtgatgg ttaaaaattc tgaatataaa
    19201 accgaaggcc gaattcctgc ctacaattat tatcacgtcc agcagaaatt gcagtgcatt
    19261 tgggcgaata acacctgcta ttcctaaccg aatgatgagg acaagatgat gaataaagac
    19321 gaagccggcg gtaactggaa acagtttaaa ggtaaaatga aagaacaatg gggcaaactg
    19381 accgatgacg atatgaccgt tatcgaaggt aaacgcgacc aactggtagg taaaatccag
    19441 gagcgttacg gttaccagaa agatcaggcg gaaaaagagg ttgttgactg ggaaacccgt
    19501 aacaactatc gctggtaata tgttttcccc tatcaggagt acatggatgt gcttcccact
    19561 gtttgcttat gaatgcgggc gtgcccctct ctactgccgc ccgtttttcc gttcaggcta
    19621 acgcggtttt ttcttcacca gcaccgagtg atcgtgacca cagtcgcccg gatggcgaca
    19681 cgcttccact tctacgcacg cagggcacag accgtgcgcc tcaataacgt tatgtcgtag
    19741 cgcaaagccc attttagccg ccagcgtatg catgatgtct tccacgccct cggcacactc
    19801 ttccttcacc acgccgcaac gatcgcagat aaacatggcc gagctgtgcg tcggctggtc
    19861 gaacaggtgg caaaccacat aactattggt ggattccact ttatggacaa aaccctgttc
    19921 gagcaaaaaa tccagcgcgc ggtagatggt gggcggtttg gcctgtggtt ccgtttcgcg
    19981 cagcaaatcg agcaaatcgt atgcgctgat ggcaccctgt tgcagactca tcaggcgcag
    20041 cacttcgagg cgctgaggcg tcaggcgcac gttgcgctgc gcgcagagtt tttcagcttg
    20101 cgccagtaac tcttgcgttg tggtcttttc catgtagcac ctcgaatggc atgaaagtct
    20161 aatccgttac tttaccacga gctgcttaaa actctgaaat taccccgcga caatatatcg
    20221 cctgctaagc ttttccgcgc cagtattctc atctatacat aatgagggtc gatattataa
    20281 caacaggatt taacatcact atttcacagc aatagttcgc ctctgtccgg taaagcgtgg
    20341 cggagggatt acttcacctg ataataagat gggctaactg tgaacaaaaa cgtcaaactt
    20401 tcactgattg ctatcgcggt ctcgcttttt atgacaaagc aggcgggcgc cgccaatacc
    20461 tggacggaag cgcgtaatga cgcaatgggc gggacgggcg ttgcgtccgc gaattatggc
    20521 agcggagtac tattaaatcc ggcgttactg gcaaaagcca aaccggaaga caatatcact
    20581 gttgtccttc ctgcggtcgg cgtccagatt acggataaag acaatctcca ggatgaaatt
    20641 gacgatatca gcgataaagt ggattactac gatgaggtcg tcgataacct tacgctgggg
    20701 caaattctgc tcaatccgcg aggcgtgctg aatcaatttc agggcgccgc gcgcgacctg
    20761 gccgatgagc tggaatatct caacggaaaa accgcccgcg ccaatgccgg cgccgggttg
    20821 gcggtaagta ttccagggca aacgctttcc gtggcgttta tcgccaaagg ttatgcgcat
    20881 gggcgcgtga gttcgtccat tgatcagaac gatattcagt atctgcgcga tatccagcat
    20941 gatgaacgtg tcgcgcttcg tgaagcagga cgcgctgctt tgctggggtc tgacgaaatt
    21001 acaaagcatt taaactctac cgcgttgggg cgggtagcga ttgtatctga ctacggtatt
    21061 gcgctggcga agcagtttgt ggtgggcgag gtgcctgttt ccattggcgt tacgccaaaa
    21121 ctgcaaaaaa cctggctcta taactacacc acctcaattt ataactacga cagtagcgac
    21181 tggaatagca gccgttatcg caatgacgat acgggtttta acattgatgc ggggcttgct
    21241 gccgatatcg gtgaaaactg gacgttgggg ctgagcgggc aaaatctggt atctcgcgat
    21301 atcgatacga aagatattta catcactaat ggtatgacgg gagaaaccac caactacaaa
    21361 gagacatacc aaatccgccc cctggttacc gcgggcatcg catggcataa cgatttgctg
    21421 accgtaagcg ccgatggcga tctgacggaa acgaaaggct ttaagagcga agacaattca
    21481 cagtacgttg gcgtcggcgc tgaagttcga ccgttgtcat ggctggcggt gcgcgcaggg
    21541 tatcgtgcgg atgtgaaaaa taacgatagc aatgtggtta ccggcggtct tggctttgcg
    21601 ccctttaacc gtgcgcatct cgatttaatg ggactgtacg gcgaagatga aacctggggg
    21661 gcaggcgcgc agcttacaat gacattctga ggtgctttca ccggaggcgc tacgcctccg
    21721 gtttagcgtt atgctatagt aacgcccctt ttttaaccgg atgcttattt attcgccatg
    21781 cagcctgaaa cccagtcctc cgctttacct gcttatcgct tctccatcgc gcctatgctc
    21841 gactggacgg acagacattg ccgctatttc ctgcgtttgc tgtctcgcca gacgctgctc
    21901 tacaccgaaa tggtgaccac gggcgcgatt attcacggta agggtgacta tctggcttat
    21961 agcgaagaag agcatccggt cgctctacag cttggtggaa gcgatccggc tcagcttgcg
    22021 cattgtgcaa agctggcgga agcgcgtggc tacgatgaaa ttaacctcaa cgtggggtgc
    22081 ccttccgatc gcgtgcaaaa tggtatgttt ggcgcctgtt tgatgggcaa tgcgcaactg
    22141 gtcgccgatt gtgttaaagc catgcgtgat gtcgtctcga ttccggtgac ggtaaaaacc
    22201 cgcattggta ttgacgatca ggacagttat gcgttcctgt gtgatttcat taatacggtt
    22261 tccggtcagg gcgaatgcga gatgtttatt atccatgcgc gcaaagcctg gctttctggc
    22321 ttaagcccga aagaaaatcg tgagatcccg ccgctggatt acccgcgcgt ctatcagcta
    22381 aagcgggatt ttccgcacct gaccatgtcc attaacggcg gcatcaaatc gttggaagag
    22441 gcgaaggaac acttgcgcca tatggatggc gtcatggttg gccgcgaagc ttatcagaat
    22501 ccgggtatac tggccgcggt ggatcgggag atctttggcg ccgataccac cgataccgac
    22561 ccggttgcgg tggttcgcgc gatgtatccc tatattgagc gtgaattgag ccagggagcg
    22621 tatctggggc atatcactcg ccatatgctg gggttgttcc agggtatccc cggcgcgcga
    22681 cagtggcgtc gctatctgag cgaaaacgcc cataaagctg gcgcggatgc tgctgtactg
    22741 gagcaggcgc taaaactgat agcagacaag cgttaaaagt tcgccaaaaa ttagtcaatc
    22801 tcaccacgct ctgcgcagtt ttgcagggcg ttttctttat atatcaaaaa cataaatatt
    22861 ggcatgattt ttgtaatagc ttacctgacc aaacccggta agcgccgtgc cgccgggcaa
    22921 tgccatcttt atggggagcg actatgctgg aactactttt tgtgcttggc ttttttctga
    22981 tgttaatggt gacgggcgtc tccttgctgg gcattctggc cgcgctggtt gtagcgactg
    23041 ccgtcatgtt cttgggcgga atgttcgccc tgatgatcaa gctgttaccg tggctactgc
    23101 tggcggtggc tgtggtgtgg gtgatcaaag cagtaaaaac gccaaaaatc ccacagtatc
    23161 agcgcaataa ccgtcggttt tactaaggta ttgagcggtt cgtcacaacc tggaactttg
    23221 ccgtcacaag caaataggaa tcgattatta aatctgtcat gattgcgcag gtaacgaatt
    23281 catcgcgctg taccctacat acagccgaac aaaaaaagaa agggcttccc gggtggaagc
    23341 ccaatttctt tgcagagcta ttacggaatc agcaggcttg agccctgtgt ggcccggctt
    23401 tccagcacct catgcgcgcg acgggcatct tttaacgcat agcgttgatt ttcagccaca
    23461 tcaactttaa tcacgccgct ggcgatcaat gagaacaatt cattgctggc ttcggtcagt
    23521 tcttcacgcg tcgtaatata cccctgtagt gaaggtcgcg tggcatacag ggaacctttc
    23581 tgattcagaa tacctaaatt cacgccggtg acggggccgg acgcattgcc gaaactgacc
    23641 atcagtcccc gacgttgcag gcagtccagt gaggcttccc aggtatcttt ccccacggag
    23701 tcatagacca cgcggacttt tttgccgccg gtgatctctt ttacccgttc gacaatgctc
    23761 tcctcacggt aattaatcac ctgccaggcg ccggcgtcca gcgcccgctg cgctttttgc
    23821 gcgctaccga cggtaccgat aagcttcgcg cccagcgctt tcgcccattg gcaggcgatc
    23881 agaccgacgc cgcccgcagc ggcatgaaac aggaagggtt cgtcgggttt cacttcatag
    23941 gttttgcgca acaggtaaaa aacggtcaat cccttgagaa aagaggctgc cgcctgttcg
    24001 aaagaaatgg cgtcaggcaa aatcgcggct ttatctgcgg ggacgttatg gacggaactg
    24061 taagcgccga gcgttgactg cgcgtagacg acgcgatcgc ccacgcgaat gtgctccacg
    24121 ccgctgccga ctttactgac cacacccgca gcttcggttc ccaggcccgc aggcaacgac
    24181 gggggcggat agagtccgct acggatatag gtgtcgatga agttgatacc aatggctttg
    24241 ttctcaacct ggatttcgtg ttccgccggt tccgttggcg taaactccac ggtctgaagc
    24301 acttccggac caccatgctt gtgaaattca atacgcgttg ccatgcttcc tccaaaagaa
    24361 atgtggtaat ctttcgaccc aatcactatc tcggtaactc cattcactat ggcaggaaat
    24421 aaacccttca acaaaccaca gactgatgcc cgcgaccgcg atccgcaggt tgccgggata
    24481 aaagtgccgc cgcactcgat tgaagcggaa cagtcggtgt tgggcggttt aatgctggat
    24541 aacgagcgct gggacgatgt ggccgagcgc gtggtggcgg aagatttcta tacccgcccg
    24601 catcgccata tctttacgga gatggggcgc ttgcaggaaa gcggcagtcc tatcgacctg
    24661 attacgctcg cggaatcgct ggagcggcag ggccaactgg acagcgtcgg cggtttcgcc
    24721 tatctggcgg agctgtctaa aaacacgcca agcgcggcga atatcagtgc ttatgcggac
    24781 attgtgcgcg aacgcgccgt ggtccgcgat atgatcgcgg tggcgcatga aattgcggac
    24841 gccggttacg atccacaggg gcgcaatagc gacgaactgc tggatctggc ggagtcgcgc
    24901 gtcttccaga tcgcggaaaa ccgggccaac aaagacgaag gtccgaaaag catcgaccag
    24961 attctcgacg ccaccgtggc gcgtattgag cagttgttcc agcaaccgca cgatggcgtt
    25021 acaggcgtgg ataccggcta tcaggatctc aataaaaaga cggcaggatt acagcgttcg
    25081 gatttgatta tcgtcgcggc gcgtccctcc atgggtaaaa ccacttttgc gatgaacctc
    25141 tgcgaaaatg cggcgatgtt gcaggataaa ccagtactga tcttcagcct ggagatgccc
    25201 ggcgaacaga tcatgatgcg tatgctggcc tcgctgtccc gcgtcgatca gacacgtatt
    25261 cgtaccggtc aactcgatga tgaagactgg gcgcgaatct ccggcacgat gggcattctg
    25321 ctggagaaac gcaatatgta tattgacgac tcctcaggtc ttacgccgac agaagtccgt
    25381 tcgcgcgcgc ggcgtatttt ccgcgaacat ggcgggttaa gtctgattat gatcgactac
    25441 ctgcaattga tgcgtgtgcc gtcgctttct gataaccgta ctctggaaat cgccgaaatt
    25501 tctcgctcgt tgaaagcgct ggcgaaggaa ctccaggtgc cggtcgtggc gctatcgcag
    25561 cttaaccgct ccctggaaca acgcgcggat aaacgtccgg tgaactccga cctgcgtgaa
    25621 tccggctcta ttgaacagga tgccgactta attatgttta tctaccgtga tgaggtttat
    25681 cacgagaaca gcgacttaaa aggcattgct gaaattatta ttggtaagca gcgtaacggt
    25741 cctatcggta cggttcgtct gacgttcaat ggtcagtggt cgcgcttcga taactatgcg
    25801 ggaccgcaat acgatgatga gtaactctcc gtcattcttt taacaaggaa ttcaaatgca
    25861 agcggcaaca gtcgtcatta accgccgcgc tctgcgacac aacctgcaac gtctgcgtga
    25921 actggcgcct gccagtaagc tggttgcggt ggtgaaagcg aacgcttatg gacacggtct
    25981 tctggagacc gcgcgaacgc tccctgatgc tgatgctttt ggcgtggcgc gtcttgaaga
    26041 ggctctacgt ctgcgagcgg gcgggattac gcagcctatc ctgctgctgg agggtttttt
    26101 cgacgccgcc gatttgccta ccatttccgc gcaatgtctg cataccgccg tacataatca
    26161 ggagcagctt gccgccctgg aggcggtgga gctggcggag ccggtaacgg tctggatgaa
    26221 gctggatacc ggtatgcatc gtctcggcgt gcgtcccgaa gaggcggagg cgttctacca
    26281 gcgtctgacg cactgtaaaa atgtacgcca gccggtgaat atcgtcagcc attttgcccg
    26341 tgcggatgag ccggaatgcg gcgctaccga acatcagctc gacattttta atgccttctg
    26401 tcagggtaaa cccggtcagc gctctattgc cgcgtctggc ggtatcctgc tgtggccgca
    26461 gtctcacttt gactgggcgc gtccgggcat cattttgtat ggcgtatcgc cgctggagca
    26521 caaaccttgg gggccggatt ttggttttca gccggtgatg tccttaactt ccagtttgat
    26581 cgcggtgcgt gaccacaaag cgggcgaacc ggtgggctac ggcgggacat gggtgagtga
    26641 gcgcgacacg cgcctgggcg tggtggcgat gggttatggc gatggctacc cacgagcggc
    26701 gccttccggt acgccagtac tggtcaatgg tcgtgaagtc ccgattgtcg ggcgggtggc
    26761 gatggatatg atttgcgtgg atttggggcc aaacgcgcag gataacgcgg gcgatccggt
    26821 ggtcttatgg ggtgaaggtc tgccggttga acgtatcgct gaaatgacaa aagtaagtgc
    26881 ttacgaactt attacgcgcc tgacctcaag ggtggcaatg aagtatattg attaaatgcg
    26941 cggcgggccg ggtggcgctt gcgcttatcc ggcttgtatc gcgcatgggc tgcaggccgg
    27001 ataagacgtt cacgccgtca tccggtaata tgcgcatcca ccacaacatc ctctcgatct
    27061 tctcgtcctt ccggtttatt gtgttatttc ctgccctctg taaacctgga gaaccatcgc
    27121 gtgtttcaaa aagttgacgc ctatgccggc gatccgattc tttcactgat ggagcgtttt
    27181 aaagacgact cccgtcacga caaagtaaat ctgagcattg gcctgtatta caacgaagac
    27241 gggattatcc cacagctcaa aacggtggcc gaagccgaag cccggcttaa cgcgcagccg
    27301 catggcgcct cgctgtacct gccgatggaa ggactcaata cttatcgcca tactatcgcg
    27361 cctttgctct ttggcgccga tcacccggtt cttcagcaac agcgcgtggc cactatccag
    27421 acattaggtg gttcaggcgc gctgaaagtg ggcgcggatt ttctgaagcg ttatttcccc
    27481 gacgcaggcg tatgggtgag cgaccctacc tgggaaaacc atattgcgat atttgccggg
    27541 gcaggattcg aagtgagtac ttacccctgg tatgacgacg cgactaacgg catccgtttt
    27601 aacgatctgc tggccacgct gaatacgtta cctgcgcgca gtatcgtgct gctgcacccc
    27661 tgttgtcaca acccgaccgg ggcggattta acgccttcgc aatgggatgc ggtgattgag
    27721 atagtgaaag cgcgcgatct gattccgttc cttgatattg cctatcaggg gtttggcgca
    27781 ggcatggacg aggatgctta cgctattcgc gccattgcca gcgccgggtt acctgcgtta
    27841 gtcagtaatt ctttttcgaa gattttctcg ctgtatggcg agtgcgtcgg cggcctgtcg
    27901 gtggtgtgtg aagatgccga aatcgccgcg cgggttctgg gacagctaaa agcgacggtg
    27961 cgccgaattt actccagtcc gccgtgtttc ggcgctcagg tggtcgctac ggtcctgggc
    28021 gatgaggcgt taaaagcgag ctggctggcg gaagtcgacg cgatgcgtac ccgcattata
    28081 tcgatgcgcc agacgctggt gaaagagctg aaggcggaga tgcctgaccg caacttcgat
    28141 tacttgttac agcagcgtgg tatgttcagc tataccgggt taagcgcgga gcaggtcgat
    28201 cggttgcgcg atgagtttgg cgtttacctg attgccagtg gccgcatgtg tgtcgctggg
    28261 cttaatgctt caaatgtaca ccgcgtggcg aaggcatttg ccgctgtcat gtaatattca
    28321 ggccggacgg cgataacagt gctctccggt ctgacaatag ctgttgtgat catcctcttt
    28381 tttcgtaaca aaaccgcaaa taatccttcc ttttgaccgt tactggcgtt atggtcagat
    28441 agttttttga ccaaagactc atcttaataa ttataatatt ttgaatttta agggaaaagc
    28501 atgaaaaaaa taaccctggc gctgagcgcc gtctgtttat tgtttacgct aaaccattcc
    28561 gcgaatgcgt tagtatcttc cccttcgacg ctcaatccgg gcactaatgt tgcaaaactc
    28621 gcggaacaag cacctgtcca ttgggtctct gtcgcccaga ttgaaaacag cctgaccgga
    28681 cgcccgccga tggcggtcgg ctttgatatt gacgacaccg tgttattttc cagccccgga
    28741 ttctggcgcg gaaagaaaac ctattccccg gacagcgacg attatctgaa aaatccggcc
    28801 ttttgggaaa aaatgaacaa cggctgggat gagttcagta ttccaaaaga agtggcccga
    28861 cagctcattg atatgcatgt tcgccgtggc gacagtattt actttgtcac tggtcgtagt
    28921 cagacgaaaa cggaaactgt gtcgaaaacg ctggcggata acttccatat tccggcggcg
    28981 aatatgaatc cggtgatttt cgccggcgat aaaccgggac aaaatacgaa agtccagtgg
    29041 ctgcaggaga agaacatgcg tatcttctac ggcgattcgg ataacgatat taccgcagct
    29101 cgtgattgtg gtatccgcgg tattcgtatc ctgcgcgcgg ctaactccac ctacaaaccg
    29161 ctgccgcagg caggagcgtt tggcgaggaa gtcattgtca actcggagta ctaaaaatca
    29221 ggagagcgac aggctctcct tttttgcatg atttttgcac aaacttgccc cgctggcttt
    29281 taccttttcc agacttgctg cacactattc aggagacgtt tgtttttagg aaggagcagc
    29341 ctatgtggta tcagcgcacc attacactga gcgagaagcc gcgcgggttt catctaataa
    29401 cagatgaaat taccgataaa ttgtctggct taccgcctgt cgaaacgggt ttgctgcatc
    29461 tgttgttgct acatacctcg gcctcgctga cgttaaacga aaactgcgat cccaccgtgc
    29521 gcgctgatat ggagcgccat ttcctgaaaa ccgttcccga taatgcggcg tatgaacatg
    29581 attacgaagg ggcggatgac atgccttcgc atattaagtc gtcagtattg ggcgtctcgt
    29641 tgctgctgcc tgtacgccag gggcgtttac agttaggaac atggcaaggt atctggttgg
    29701 gagagcaccg tattcacggc ggtccacgta aaatcatcgc gacactacaa ggggaatgat
    29761 aatgaccatt tcggaattac tgcaatactg catggcaaaa cctggcgcag agcagagcgt
    29821 tcacagcgac tggaaagcga cgcaaattaa agtggaagat gtacttttcg cgatggtaaa
    29881 agaagttgat gggcgcccgg cagcctctct caaaaccagc ccggaactgg cagagttgtt
    29941 acgccagcag cacagcgatg ttcgatcgag tcggcacctt aataaagcgc actggagtac
    30001 ggtctatctg gacggctcgc tgccggattc acaactctat tatctggtcg atgcctctta
    30061 tcaacaggcg gtaaatgcgc tgtcggaaga taaacgcaag cagttgccgc agtcctgatt
    30121 atagcgcgcc gaccaacaac gccagggcga tatcaatgag gtggatgacc gtagaccgga
    30181 tacggctgcc gagggcaatt tgcgcattat tggcgcgtag cctggcgagg tcccgctgtc
    30241 cttccagcag aataatcata tcgtcgtcgt ccagccagcc gcgagcatgt tcctgaagcg
    30301 cgcgggcgat aaacgcggcg gactcgcgga taccgtcgtc gctgtcttct cttgcctgct
    30361 tatacgtctg gataaactcg gcaattgccg aggaggctac aggatgttcg gcccgggcgg
    30421 cagtaaacag gttacgtatt tcgttaatag acgccatttt cttctccctg agtgcagcgg
    30481 gcgccccaat gcagacactc accctgtatg gctaatttcc agacctgatt attttgctgt
    30541 tggtatctct cagcctggat gtaagtaagt ggttgcttac atttcataac ccgcgcataa
    30601 agacgcaaat agtgattttt cagcagcgcc agattatcga gtcggtgttt atccccacct
    30661 tgacgggcga cccgctcagc ctgaaaaaat gtctggcgga tatcgcggtc atctttgagc
    30721 agtgtctctt tttgccacgg tattcgcgcc gcgtcctgca ggaagcgggt tgagcgcgct
    30781 tgtaatagcg tcagttgttg aaaagccacg gcgctaaagc ggtcaggcag cgtacaggcg
    30841 gctaaaaaca ggcacagcag tagtgtgatt gcgtagggca acttcatggt gttttccata
    30901 acagaccgtt tgcgctatca catgtcagag cgaggcggca cgcaaatcac aaatgctcaa
    30961 cacggataca atgaggtggg atgaggaaaa atgatgccgc ttcccggcga atcggaaagc
    31021 ggtgtgaagg ttatttgagc ataggtttaa ggaagcgggc ggtatgcgac gcctcgcact
    31081 ccgccacggt ttccggcgta ccggcgacga gaatttcgcc gccgccgctg ccgccttccg
    31141 ggccgaggtc gacaatccag tccgccgttt taatgacgtc caggttgtgt tcgatcacca
    31201 cgatggtgtt gccctgatcg cgcaactgat gcagcacgtc aagcaactgc tgaatatcgg
    31261 caaagtgcag gccggtggtc ggctcgtcga gaatatacag cgtctgcccg gtgccacgtt
    31321 tcgacagttc gcgcgccagc ttcacgcgct gggcctcgcc gccggaaagc gtcgtcgccg
    31381 actgaccaag acggatatag gtcagcccca cgtccatcag cgtctgcagc ttacgcgcca
    31441 gcgccggaac cgcatcaaag aactcacgcg cttcttcaat ggtcatatcc agcacttcgt
    31501 ggatggtctt gcctttgtac ttaatctcca gcgtttcccg gttatagcgc ttgcctttgc
    31561 actggtcgca cggcacgtaa atatccggca gaaagtgcat ttcgacttta atgacgccat
    31621 cgccctggca cgcttcgcag cgaccgccgc gcacgttgaa gctgaatcgc cctggcgtgt
    31681 agccgcgcga gcgagactcc ggcacgccag caaaaagctc acgaaccggg gtaaagacgc
    31741 ccgtataggt cgccgggttg gaacgcgggg tgcgcccgat cgggctctgg tcgatatcga
    31801 tcactttatc gaaatgttcc agcccctgaa tatcccgata cggcgccggt tcggcgatag
    31861 tcgccccgtt taactgacgc tgggcgatgg ggaacagcgt atcgttaatc agcgtcgatt
    31921 taccggaacc cgagacgccg gtgatacagg taaacagccc taccggtagc gtaagggtca
    31981 catctttcag gttgttgccg cgcgcgccgg tgagtttgag cactttttct ggatttgccg
    32041 gcacgcgttg tttcggcact tcaattttgc gtttaccgct catgtactgg ccggtcagcg
    32101 attccggtac cgccataatg gcttccagcg ggccttccgc caccacctcg ccgccgtgaa
    32161 cgcccgcgcc ggggccaata tcaatcacat ggtcggcggc gcggatggcg tcttcatcgt
    32221 gttccaccac aatcacggta ttgccaagat tgcgcagatg aatcagcgta cccagcagcc
    32281 gttcgttatc gcgctggtgc agaccgatgg acggttcatc cagcacatac atcacgccga
    32341 ctaacccggc gcctatctgg ctcgccagac gaatacgctg ggcttcgccg ccggaaagcg
    32401 tctctgccga gcgggagagc gtgagatagt tcaggccgac gttcaccaga aacttgaggc
    32461 gatcgccgat ctcttttagc actttttcgg cgattttcgc ccgttgcccg gaaagcttga
    32521 gattagtgaa aaaatccatc gcatggccaa tgctcatatc ggaaatagca ggcagcggcg
    32581 tattttccac aaatacatgg cgcgcttcgc gattcagtcg cgttccttca cagctggcgc
    32641 aggggcgatt actgatgaat ttcgccagct cttcgcgcac cgcgctggat tccgtctctt
    32701 tataacggcg ctccatatta tgcagcacgc cttcgaacgg atggcggcgc acggaggtat
    32761 cgccgcgatc gttcatatat ttaaattcga tgttctcttt gccggaaccg tacagcacga
    32821 ctttgtgtac gttggcgctg aggcttgccc acggcgcatc cacgtcgaac ttatagtgtt
    32881 ccgccagcga cttgagcatt tgaaagtagt aaaaattgcg acgatcccaa ccacgaatcg
    32941 cgccgcctgc cagcgacagg tcgggattct ggatcacgcg gtccggatcg aaatattgct
    33001 gaacgccgag cccgtcacag gtcggacagg cgcctgccgg gttgttgaac gagaacagac
    33061 gcggttccag ctcgcgcata ctgtagccgc aaatcgggca ggcaaaattg gcggagaaca
    33121 gaagctcctc cgctttctca tcgtccatat cggcaacaac cgccgtgccg ccggataatt
    33181 ccagcgccgt ttcgaacgac tccgccaggc gttgggaaag atcgttacga actttgaagc
    33241 gatcgatcac cacctcaatg gtatgtttct tttgtagctc cagcttcggc ggatcggaga
    33301 gatcgcagac ttcgccgtca atacgggcgc gaatgtaacc ctggcttgcc agattttcca
    33361 gcgttttggt gtgttcgcct ttacgctctt taataatcgg cgccagcagc atcaggcgtt
    33421 tgccttccgg ctgcgacagc acgttatcga ccatctggct aacggtttgc gccgccagcg
    33481 gcacgtcatg gtccggacaa cgcggctcgc ccacgcgggc aaacagcagg cgcaggtagt
    33541 cgtggatctc ggtaatagta cccaccgtag agcgcgggtt gtgcgatgtc gatttctgtt
    33601 caattgagat cgcgggcgat agcccctcaa tatggtcgac atccggtttt tccatgagcg
    33661 acaaaaactg ccgcgcgtaa gcggagagcg attcaacgta acgacgctgc ccttcggcat
    33721 acagagtgtc gaaagccagt gaggatttgc ctgaacccga aagcccggtc acgacaatca
    33781 gtttgtcgcg ggggatgacg aggttaatat ttttgagatt atgggtgcgg gcgccccgaa
    33841 cttcgatctt atccattcac ctttcccggt agagactcgg atgcctggtt tgtttgaagg
    33901 acaaacggca gaaacggcta attatgacac aatttaacct gtttgaatat acagtattgg
    33961 aatgcatctt cagctaaagt atgcaacaat atgaggttcg cgcgagtgac ctggaacctg
    34021 catcgcagct attaaaatgc tacgtggaaa tggtacactc acgcgtttac actatttatg
    34081 aaacgtattc aggagactca attatggcca gcagaggcgt aaacaaggtg attctcgttg
    34141 gtaatctggg ccaggacccg gaagtacgct atatgccgag tggcggtgct gtcgccaact
    34201 taacgctggc tacttctgaa tcctggcgcg ataagcagac cggcgaaatg aaagagcaga
    34261 ctgaatggca ccgggtggtg atgttcggca aactggcgga agtggccggc gaatatctgc
    34321 gtaaaggttc tcaggtgtat atcgaaggtc aattgcgtac ccgcaagtgg accgatcaga
    34381 gtggccagga acgctatacg actgaaatta acgttccgca gatcggcggc gtgatgcaga
    34441 tgctgggtgg tcgccagggc ggcggcgcac cggcaggcgg tcagcagcag gggggttggg
    34501 gtcagccgca acaacctcag cagccgcagg gcggtaacca gttcagcggc ggcgcgcagt
    34561 cgcgtccaca gcaatccgcg ccagcgccgt ctaacgaacc gccaatggat tttgacgacg
    34621 acattccgtt ctgatttttg gtaaaaaact caaagcgtta tttgcatttt cgctatagtt
    34681 ctcgtctgct gaaatgcctg gtgtaaacca ggcattttat tacctggtat tattgtctta
    34741 gtatcccttt caaaaaagag aagcgcatat ctcacggaat gacttacgga aaaatgtcgc
    34801 ttatcgcctc tggccgactc gcctcggcac atcattatcc agccgaagtt cataaatgta
    34861 ctgcaataac ccggattgtc ttaaatatg
//
LOCUS       DAJVBX010000019        33241 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.019, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000019 DAJVBX010000000
VERSION     DAJVBX010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 33241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33241
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.019"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            74..1213
                     /gene="arnB"
                     /locus_tag="OPV72_000851"
     CDS             74..1213
                     /gene="arnB"
                     /locus_tag="OPV72_000851"
                     /EC_number="2.6.1.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_024188371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-4-amino-4-deoxy-L-arabinose
                     aminotransferase"
                     /protein_id="HCR9913223.1"
                     /translation="MSDFLPFSRPAMGAEELAAVKTVLDSGWITTGPKNQELEAAFCR
                     LTGNQYAVAVSSATAGMHIALMALGIGEGDEVITPSMTWVSTLNMIVLLGATPVMVDV
                     DRDTLMVTPEHIEAAITPQTKAIIPVHYAGAPADLDAIYALGARYGIPVIEDAAHATG
                     TSYKGRHIGARGTAIFSFHAIKNITCAEGGIVVTDNPQFADKLRSLKFHGLGVDAWDR
                     QSGGRAPQAEVLAPGYKYNLPDFNAAIALAQLQKLDALNARRAAIAAQYHQAMADLPF
                     QPLSLPPWEHIHAWHLFIIRVDEARCGITRDALMASLKTKGIGTGLHFRAAHTQKYYR
                     ERFPTLTLPDTEWNSERICSLPLFPDMTESDFDRVITALHQIAGQ"
     gene            1216..2199
                     /gene="arnC"
                     /locus_tag="OPV72_000852"
     CDS             1216..2199
                     /gene="arnC"
                     /locus_tag="OPV72_000852"
                     /EC_number="2.4.2.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-phosphate
                     4-deoxy-4-formamido-L-arabinose transferase"
                     /protein_id="HCR9913224.1"
                     /translation="MFDAAPIKKVSVVIPVYNEQESLPELIRRTTTACESLGKAWEIL
                     LIDDGSSDSSAELMVKASQEADSHIISILLNRNYGQHAAIMAGFSHVSGDLIITLDAD
                     LQNPPEEIPRLVAKADEGFDVVGTVRQNRQDSLFRKSASKIINLLIQRTTGKAMGDYG
                     CMLRAYRRPIIDTMLRCHERSTFIPILANIFARRATEIPVHHAEREFGDSKYSFMRLI
                     NLMYDLVTCLTTTPLRLLSLLGSVIAIGGFSLSVLLIVLRLALGPQWAAEGVFMLFAV
                     LFTFIGAQFIGMGLLGEYIGRIYNDVRARPRYFVQQVIYPESTSFTEESHQ"
     gene            2196..4178
                     /gene="arnA"
                     /locus_tag="OPV72_000853"
     CDS             2196..4178
                     /gene="arnA"
                     /locus_tag="OPV72_000853"
                     /EC_number="1.1.1.305"
                     /EC_number="2.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-4-amino-4-deoxy-L-arabinose
                     formyltransferase/UDP-glucuronic acid oxidase ArnA"
                     /protein_id="HCR9913225.1"
                     /translation="MKAVIFAYHDMGCQGVQAVLDAGYEIAAIFTHADNPAENTFFGS
                     VSRLAAGLGIPVYAPDNVNHPIWVDRIAELAPDIIFSFYYRNLLSEEILHLAPAGAFN
                     LHGSLLPAYRGRAPLNWVLVNGESETGVTLHRMVKRADAGEIVASQRVAIAQDDVALT
                     LHHKLCQAARQLLNSILPTMKCGNIPSVPQRESDATYYGRRRPEDGLIDWHKPVSTVH
                     NLVRAVAAPWPGAFSYNGSQKFTIWSSRICPDAQGALPGSVISVSPLRVACADGALEI
                     ITGQAGDGITVQGSQLAQTLGLVAGACLNRPPATSGKRRIRVLILGVNGFIGNHLTER
                     LLDEENYEVYGMDIGSNAISRFLLHPRFHFVEGDISIHSEWIEYHVKKCDVVLPLVAI
                     ATPIEYTRNPLRVFELDFEENLRIIRYCVKYRKRVVFPSTSEVYGMCTDASFDEDKSN
                     LIVGPVNKPRWIYSVSKQLLDRVIWAYGEKEGLRFTLFRPFNWMGPRLDSLNAARIGS
                     SRAITQLILNLVEGTPIKLIDGGQQKRCFTDIRDGIEALFRIIVNEGDRCDGKIINIG
                     NPDNEASIQELATLLLDSFDKHPLRCHFPPFAGFQVVESRSYYGKGYQDVAHRKPSID
                     NARRCLDWEPSIAMRDTVEETLDFFLRSVDIAERAS"
     gene            4175..5074
                     /locus_tag="OPV72_000854"
     CDS             4175..5074
                     /locus_tag="OPV72_000854"
                     /EC_number="3.5.1.n3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-deoxy-4-formamido-L-arabinose-
                     phosphoundecaprenol deformylase"
                     /protein_id="HCR9913226.1"
                     /translation="MTKVGLRIDVDTLRGTREGVPRLLATLHRHGVQASFFFSVGPDN
                     MGRHLWRLIKPRFLWKMLRSNAASLYGWDILLAGTAWPGKNIGNANAGIIRETATYHE
                     TGLHAWDHHAWQTHSGHWSIRQLEEDIARGITALEAIIGKPVTCSAAAGWRADGRVVR
                     AKEPFNLRYNSDCRGTTLFRPLLMPGQTGTPQIPVTLPTWDEVIGPAVQAQSFNTWII
                     SRMLQDKGTPVYTIHAEVEGIVHQPLFEDLLVRARDAGITFCPLGELLPASPESLPLG
                     QIVRGHIPGREGWLGCQQAVSAS"
     gene            5071..6717
                     /gene="arnT"
                     /locus_tag="OPV72_000855"
     CDS             5071..6717
                     /gene="arnT"
                     /locus_tag="OPV72_000855"
                     /EC_number="2.4.2.43"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid IV(A)
                     4-amino-4-deoxy-L-arabinosyltransferase"
                     /protein_id="HCR9913227.1"
                     /translation="MMKSIRYYLAFAAFIALYYVIPVNSRLLWQPDETRYAEISREML
                     ASGDWIVPHFLGLRYFEKPIAGYWINSLGQWLFGATNFGVRAGAILTTLLAAALVAWL
                     TFRLWRDKRTALLASVIFLSLFAVYSIGTYAVLDPMIALWLTAGMCCFWQGMQATTRT
                     GKIGMFLLLGATCGLGVLTKGFLALAVPVVSVLPWVIVQKRWKDFLLYGWLAVLSCFV
                     VVLPWAIAIARREADFWHYFFWVEHIQRFAMSDAQHKAPFWYYLPVLLAGSLPWLGLL
                     PGALKLGWRERNGAFYLLGWTIMPLLFFSIAKGKLPTYVLSCFAPIAILMARFVLHNV
                     KEGVAALRVNGGINLVFGIIGIVAAFVVSSWGPLKSPVWTHIETYKVFCVWGVFTVWA
                     FVGWYSLCHSPKYLLPAFCPLGLALLFGFSVPDRVMESKQPQFFVEMTQAPLASSRYI
                     LADSVGVAAGLAWSLKRDDIMLYGHAGELRYGLSYPDVQNKFVKADDFNAWLNQHRQE
                     GIITLVLSIDKDEDISALSLPPADNVDYQGRLVLIQYRPK"
     gene            6714..7049
                     /gene="arnE"
                     /locus_tag="OPV72_000856"
     CDS             6714..7049
                     /gene="arnE"
                     /locus_tag="OPV72_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-amino-4-deoxy-L-arabinose-phosphoundecaprenol
                     flippase subunit ArnE"
                     /protein_id="HCR9913228.1"
                     /translation="MIGIVLVLASLLSVGGQLCQKQATRPLTTGGRRRHLMLWLGLAL
                     ICMGAAMVLWLLVLQTLPVGIAYPMLSLNFVWVTLAAWKIWHEQVLPRHWLGVALIIS
                     GIIILGSAA"
     gene            7049..7426
                     /gene="arnF"
                     /locus_tag="OPV72_000857"
     CDS             7049..7426
                     /gene="arnF"
                     /locus_tag="OPV72_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-amino-4-deoxy-L-arabinose-phosphoundecaprenol
                     flippase subunit ArnF"
                     /protein_id="HCR9913229.1"
                     /translation="MGVMWGLISVAIASLAQLSLGFAMMRLPSIAHPLAFISGLGAFN
                     AATLALFAGLAGYLVSVFCWQKTLHMLALSKAYALLSLSYVLVWVASMLLPGLQGAFS
                     LKAMLGVLCIMAGVMLIFLPARS"
     gene            complement(7421..7678)
                     /gene="pmrD"
                     /locus_tag="OPV72_000858"
     CDS             complement(7421..7678)
                     /gene="pmrD"
                     /locus_tag="OPV72_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal transduction protein PmrD"
                     /protein_id="HCR9913230.1"
                     /translation="MEWLVKKSHYVKKRACHVLVLCDSGGSLKMIAEANSMILLSPGD
                     ILSPLQDAQYCINREKHQTLKIVDARCYSCDEWQRLTRKPL"
     gene            complement(7776..9143)
                     /gene="menE"
                     /locus_tag="OPV72_000859"
     CDS             complement(7776..9143)
                     /gene="menE"
                     /locus_tag="OPV72_000859"
                     /EC_number="6.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="o-succinylbenzoate--CoA ligase"
                     /protein_id="HCR9913231.1"
                     /translation="MTFTDWPWRHWRQVRSQAPALRLNDEVLSWRALCERIDALAGGF
                     AAQGVREGDGVLLRAGNQPRTLLAWLALMQCGARVLPVNPQLPQTLLEALVPKLTLRF
                     ALTLEGENAFSGLTVLQLRKSTVAYAVAWQPQRLVSMTLTSGSTGLPKAAVHTCQAHL
                     ASAQGVLSLMPFGPQDDWLLSLPLFHVSGQGIMWRWLFAGARMTVRDKQPLEQMLAGC
                     THASLVPTQLWRLLANRAAVTLKAVLLGGAVIPVELTDQASKQGIRCWCGYGLTEFAS
                     TVCAKEADGSDDVGAPLPGREIRIVDNEVWLRAASMAEGYWRDGKLIPLVNDEGWFAT
                     RDRGELNHGRLTIAGRLDNLFFSGGEGIQPEEVERVINAHPLVQQAFVVPVEDKEFGH
                     RPVAVVEYASQAGDVNLAEWVRDKLARFQQPVRWLTLPSELKNGGIKISRRALQQWVC
                     KICKN"
     gene            complement(9140..10102)
                     /gene="menC"
                     /locus_tag="OPV72_000860"
     CDS             complement(9140..10102)
                     /gene="menC"
                     /locus_tag="OPV72_000860"
                     /EC_number="4.2.1.113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="o-succinylbenzoate synthase"
                     /protein_id="HCR9913232.1"
                     /translation="MRSAQVYRWQIPMDAGVVLRDRRLKTRDGLYVCLRDGEREGWGE
                     ISPLPGFSQETWEEAQTALLTWVNDWLQGSEGLPEMPSVAFGASCALAELTGVLPEAA
                     DYRAAPLCTGDPDDLVLRLADMPGEKIAKVKVGLYEAVRDGMVVNLLLEAIPDLHLRL
                     DANRAWTPLKAQQFAKYVNPDYRARIAFLEEPCKTRDDSRAFARETGIAIAWDESLRE
                     ADFTFEAEEGVRAVVIKPTLTGSLDKVREQVAAAHALGLTAVISSSIESSLGLTQLAR
                     IAAWLTPGTLPGLDTLHLMQAQQVRPWPGNALPCLKRDELERLL"
     gene            complement(10102..10959)
                     /gene="menB"
                     /locus_tag="OPV72_000861"
     CDS             complement(10102..10959)
                     /gene="menB"
                     /locus_tag="OPV72_000861"
                     /EC_number="4.1.3.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001641973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoyl-CoA synthase"
                     /protein_id="HCR9913233.1"
                     /translation="MIYPDETMLYAPVEWHDCSEGYTDIRYEKSTDGIAKITINRPQV
                     RNAFRPLTVKEMIQALADARYDDNVGVIILTGEGDKAFCAGGDQKVRGDYGGYQDDSG
                     VHHLNVLDFQRQIRTCPKPVVAMVAGYSIGGGHVLHMMCDLTIAAENAIFGQTGPKVG
                     SFDGGWGASYMARIVGQKKAREIWFLCRQYDAQQALDMGLVNTVVPLADLEKETVRWC
                     REMLQNSPMALRCLKAALNADCDGQAGLQELAGNATMLFYMTEEGQEGRNAFNQKRQP
                     DFSKFKRNP"
     gene            complement(10974..11732)
                     /gene="menH"
                     /locus_tag="OPV72_000862"
     CDS             complement(10974..11732)
                     /gene="menH"
                     /locus_tag="OPV72_000862"
                     /EC_number="4.2.99.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-succinyl-6-hydroxy-2,
                     4-cyclohexadiene-1-carboxylate synthase"
                     /protein_id="HCR9913234.1"
                     /translation="MMLHAQHMPGQPGTPSLVFLHGFSGDCREWQPVGEQFHGCSRLY
                     IDLPGHGGSAAIPVGGFADVIRLLRATLISYNILKFWLVGYSLGGRVAMMAACQGIPG
                     LCGLVVEGGHPGLQNEQARAERRLSDGRWAERFRHEPLTEVFHDWYQQPVFASLTAQQ
                     RQALTALRSQNNGETLAAMLEATSLAVQPDLREVLNALAFPFYYLCGERDSKFRALAQ
                     EVAATCHVIRNAGHNAHRENPAGVVDSLAQILRL"
     gene            complement(11729..13399)
                     /gene="menD"
                     /locus_tag="OPV72_000863"
     CDS             complement(11729..13399)
                     /gene="menD"
                     /locus_tag="OPV72_000863"
                     /EC_number="2.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-succinyl-5-enolpyruvyl-6-hydroxy-3-
                     cyclohexene-1-carboxylic-acid synthase"
                     /protein_id="HCR9913235.1"
                     /translation="MSVSAFNRRWAAVILEALTRHGVRHVCIAPGSRSTPLTLAAAEN
                     PAFIHHTHFDERGLGHLALGLAKVSQQPVAVIVTSGTAVANLYPALIEAGLTGEKLIL
                     LTADRPPELIDCGANQAIRQAGMFASHPSQTLSLPRPTQDIPARWLVSTIDNALAMLH
                     AGALHINCPFAEPLYGDMNDTGLVWQQRLGDWWQDEKPWLREARRLASDKQRDWFFWR
                     QKRGVVVAGRMSAEEGKKVAQWAQTLGWPLIGDVLSQTGQPLPCADLWLGNAKAVTEL
                     QQAQIVVQLGSSLTGKRLLQWQATCVPEEYWVIDNIEGRLDPAHHRGRRLVAKIADWL
                     ELHPAEKRKPWCVEIPRLAELAWQRVVAQRDTFGEAQLAHRIRDYLPEQGQLFVGNSL
                     VVRLIDALSQLPAGYPVYSNRGASGIDGLLSTAAGVQRASAKSTLAIVGDLSALYDLN
                     ALALLRQVSAPFVLIVVNNNGGQIFSLLPTPQSKRERFYLMPQNVHFDHAAAMFNLRY
                     HRPENWEELESALAGAWRTPATTVIELVVNDTDGAQTLQQLLAQVSHL"
     gene            complement(13485..14780)
                     /gene="menF"
                     /locus_tag="OPV72_000864"
     CDS             complement(13485..14780)
                     /gene="menF"
                     /locus_tag="OPV72_000864"
                     /EC_number="5.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismate synthase MenF"
                     /protein_id="HCR9913236.1"
                     /translation="MHSITTALENLTRQLSQEIPATPGLCVFDAPFPLNDAFDALSWL
                     ASQSSFPQFYWQQRNGDEEAAVLGAITVFSSLDLAQRFLRQHAQPDLRIWGLNAFEPK
                     EGYLLLPRLEWRRSGGTATLRLHLHSDVSLRDDARLAKAFLASLVGIKPVPALRLSLT
                     SEQHWPDKDGWVKLIQQATHTIAQEAFDKVVLARATDLQFSRPVNAAAMMASSRRLNL
                     NCYHFFMAFSADTAFLGSSPERLWRRRETALRTEALAGTVANHPDNHKAWQLGEWLMK
                     DDKNQRENMLVVEDICQRLQNCTHSLDVLPPQVLRLRKVQHLRRCIWTALNQADDTLC
                     LHQLQPTAAVAGIPREPARCFIEQHEPFEREWYAGSAGYLSTRQSEFCVTLRSAKVTA
                     NVVRLYAGAGIVRGSDPEQEWQEIDNKAAGLRTLLQMDA"
     gene            complement(14881..15186)
                     /gene="elaB"
                     /locus_tag="OPV72_000865"
     CDS             complement(14881..15186)
                     /gene="elaB"
                     /locus_tag="OPV72_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response protein ElaB"
                     /protein_id="HCR9913237.1"
                     /translation="MSYQFGESRVDDDLTLLSETLEEVLRSSGDPADQKYIELKARAE
                     QALEEVKNRVSHASDSYYYRAKQAVYKADDYVHEKPWQGIGVGAAVGLVLGLLLARR"
     gene            complement(15241..15702)
                     /locus_tag="OPV72_000866"
     CDS             complement(15241..15702)
                     /locus_tag="OPV72_000866"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCR9913238.1"
                     /translation="MIDWQDLHHSELTVPQLYALLKLRCAVFVVEQRCPYLDVDGDDL
                     VGDNRHILGWHQDELVAYARILKSDNESDPVVIGRVIVSDAWRGAKLGQQLMAKTLES
                     CGRHWPDKPLYLGAQAHLQPFYARFGFIPVTDVYDEDGIPHRGMAREVHQA"
     gene            15763..16680
                     /gene="rbn"
                     /locus_tag="OPV72_000867"
     CDS             15763..16680
                     /gene="rbn"
                     /locus_tag="OPV72_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease BN"
                     /protein_id="HCR9913239.1"
                     /translation="MELIFLGTSAGVPTRSRNVTAILLHLQHPTQPGVWLFDCGEGTQ
                     HQMLNTAFHPGKLERIFISHLHGDHLFGLPGLLCSRSMAGNPHPLTVYGPQGVREFIA
                     TTLRLSGSWTDFPLQIEEISAGDILDDGLRKVTAFRLEHPLECYGYRVVEHDKPGALN
                     ARALKAAGVTPGPLFQALKAGKTVTLADGRQINGADYLAPAVAGKSVAIFGDTAPCEA
                     ALALAQGVDVMVHETTLDASMEEKANARGHSSTRQTATLAREAAVGRLIMTHISSRYD
                     DKGCQRLLAECRAIFPATELAYDFSVFPV"
     gene            16746..17750
                     /locus_tag="OPV72_000868"
     CDS             16746..17750
                     /locus_tag="OPV72_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012131502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheV"
                     /protein_id="HCR9913240.1"
                     /translation="MDNFQKDIDDRANLTLSNRFELLLFRLGTSLHEQKSELFGINVF
                     KLREIIPMPAFTRPAGMKAPLLGMVNIRDQVIPVIDLPAVAGCKPETGLNILLITEYV
                     RSVQAFAVESVENIMRLDWQQVHTAEKAVNGRYITSIACLDDNKETNNLALVLDVEQI
                     LYDIVPSSHDLRATNLKTNKFYITPGAVAIVAEDSKVACAMLEKGLNAMEIPHQMHVT
                     GKDAWERIQQLAQEAEAEGKPISEKIALVLTDLEMPEMDGFTLTRKIKTDERLKKIPV
                     VIHSSLSGSANEDHVRKVKADGYVAKFEINELSSVIQEVMERAAQNISGPLVSRQLLS
                     "
     gene            complement(17891..19348)
                     /gene="nuoN"
                     /locus_tag="OPV72_000869"
     CDS             complement(17891..19348)
                     /gene="nuoN"
                     /locus_tag="OPV72_000869"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416779.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoN"
                     /protein_id="HCR9913241.1"
                     /translation="MTITPQHLIALLPLLIVGLTVVVVMLSIAWRRNHFLNATLSVIG
                     LNAALVSLWFVGQAGAMDVTPLMRVDGFAMLYTGLVLLASLATCTFAYPWLEGYNDNQ
                     EEFYLLVLIASLGGILLANANHLAALFLGIELISLPLFGLIGYAFRQKRSLEASIKYT
                     ILSAAASSFLLFGMALVYAQSGNLSFEALGKSLGDGMLHEPLLLAGFGLMIVGLGFKL
                     SLVPFHLWTPDVYQGAPAPVSTFLATASKIAIFGVVMRLFLYAPVGDSEAVRVVLGII
                     AFASIIFGNLMALSQTNIKRLLGYSSISHLGYLLVALIALQSGEMSMEAVGVYLAGYL
                     FSSLGAFGVVSLMSSPFRGPDADSLYSYRGLFWHRPVLAAVMTVMMLSLAGIPMTLGF
                     IGKFYVLAVGVQASLWWLVAAVVVGSAIGLYYYLRVAVSLYLHAPQQPGRDAPTNWQY
                     SAGGIVVLISALLVLVLGVWPQPLISLVQLATPLM"
     gene            complement(19355..20884)
                     /gene="nuoM"
                     /locus_tag="OPV72_000870"
     CDS             complement(19355..20884)
                     /gene="nuoM"
                     /locus_tag="OPV72_000870"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit M"
                     /protein_id="HCR9913242.1"
                     /translation="MLLPWLILIPFIGGFLCWQTERFGVKVPRWIALITMELTLALGL
                     QLWLQGGYSLTQSAGIPQWQSEFVLPWIPRFGISIHLALDGLSLLMVVLTGLLGVLAV
                     LCSWREIEKYQGFFHLNLMWILGGVIGVFLAIDMFLFFFFWEMMLVPMYFLIALWGHK
                     ASDGKTRITAATKFFIYTQASGLVMLIAILALVFVHYKATSVWTFNYEELLNTPMSHG
                     VEYLLMLGFFIAFAVKMPVVPLHGWLPDAHSQAPTAGSVDLAGILLKTAAYGLLRFSL
                     PLFPNASAEFAPIAMWLGVIGIFYGAWMAFTQYDIKRLIAYTSVSHMGFVLIAIYTGS
                     QLAYQGAVIQMIAHGLSAAGLFILCGQLYERLHTRDMRMMGGLWGKMKWLPALSMFFA
                     VATLGMPGTGNFVGEFMILFGSYQVVPMITVISTFGLVFASVYSLAMLHRAYFGKAKS
                     QIASQELLGMSLRELFIILLLVVLLVLLGFYPQPILDTSHSAMSNIQQWFVNSVTTTR
                     P"
     gene            complement(21198..23039)
                     /gene="nuoL"
                     /locus_tag="OPV72_000871"
     CDS             complement(21198..23039)
                     /gene="nuoL"
                     /locus_tag="OPV72_000871"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit L"
                     /protein_id="HCR9913243.1"
                     /translation="MNMLALTIILPLIGFVLLAFSRGRWSENLSATIGVGSVGLAALV
                     TAFVGMDFFANGKQAFSQPLWTWMSVGNFNIGFNLVLDGLSLTMLSVVTGVGFLIHMF
                     ASWYMRGEEGYSRFFAYTNLFIASMVVLVLSDNLLLMYLGWEGVGLCSYLLIGFYYSD
                     PKNGAAAMKAFVVTRVGDVFLAFALFILYNELGTLNFREMVELAPAHFADGNNMLMWA
                     TLMLLGGAVGKSAQLPLQTWLADAMAGPTPVSALIHAATMVTAGVYLIARTHGLFLMT
                     PEILHLVGIIGAITLVMAGFAALVQTDIKRVLAYSTMSQIGYMFLALGVQAWDAAIFH
                     LMTHAFFKALLFLASGSVILACHHEQNIFKMGGLRKSIPLVYACFLVGGAALSALPLV
                     TAGFFSKDEILAGAMANGHINLMVAGLVGAFMTSLYTFRMIFIVFHGKEQIHAHAGKG
                     ITHHLPLIVLMILSTFVGALIVPPLQGVLPQTTELAHGRVLTLEITSGVVAIAGILIA
                     AWLWLGKRTLVTSIANSAPGHLLGTWWYNAWGFDWLYDKVFVKPFLGIAWLLKRDPLN
                     ALMNIPAILSRFAGKGLVLSENGYLRWYVASMSIGAVVVLALLMVLR"
     gene            complement(23036..23338)
                     /gene="nuoK"
                     /locus_tag="OPV72_000872"
     CDS             complement(23036..23338)
                     /gene="nuoK"
                     /locus_tag="OPV72_000872"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006683663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoK"
                     /protein_id="HCR9913244.1"
                     /translation="MIPLTHGLILAAILFVLGLTGLVIRRNLLFMLIGLEIMINASAL
                     AFVVAGSYWGQTDGQVMYILAISLAAAEASIGLALLLQLHRRRQNLNIDSVSEMRG"
     gene            complement(23335..23889)
                     /gene="nuoJ"
                     /locus_tag="OPV72_000873"
     CDS             complement(23335..23889)
                     /gene="nuoJ"
                     /locus_tag="OPV72_000873"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit J"
                     /protein_id="HCR9913245.1"
                     /translation="MEFAFYICGLIAILATLRVITHTNPVHALLYLVISLLAISGVFF
                     SLGAYFAGALEIIVYAGAIMVLFVFVVMMLNLGGSEIEQERQWLKPQVWIGPAVLSAI
                     MLAVIVYAILGVNDQGIDGTPISAKAVGITLFGPYVLAVELASMLLLAGLVVAFHVGR
                     EERAGEVLSNRADDRAKRKTEERA"
     gene            complement(23900..24442)
                     /gene="nuoI"
                     /locus_tag="OPV72_000874"
     CDS             complement(23900..24442)
                     /gene="nuoI"
                     /locus_tag="OPV72_000874"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015959823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoI"
                     /protein_id="HCR9913246.1"
                     /translation="MTLKELLVGFGTQVRSIWMIGLHAFAKRETRMYPEEPVYLPPRY
                     RGRIVLTRDPDGEERCVACNLCAVACPVGCISLQKAETKDGRWYPEFFRINFSRCIFC
                     GLCEEACPTTAIQLTPDFELGEYKRQDLVYEKEDLLISGPGKYPEYNFYRMAGMAIDG
                     KDKGEAENEAKPIDVKSLLP"
     gene            complement(24457..25434)
                     /gene="nuoH"
                     /locus_tag="OPV72_000875"
     CDS             complement(24457..25434)
                     /gene="nuoH"
                     /locus_tag="OPV72_000875"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015875065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoH"
                     /protein_id="HCR9913247.1"
                     /translation="MSWITPDLIEILLSILKAVVILLVVVTCGAFMSFGERRLLGLFQ
                     NRYGPNRVGWGGSLQLVADMIKMFFKEDWIPKFSDRVIFTLAPMIAFTSLLLSFAIVP
                     VSPNWVVADLNIGILFSLMMAGLAVYAVLFAGWSSNNKYSLLGAMRASAQTVSYEVFL
                     GLSLMGVVAQAGSFNMTDIVNNQAHLWNVIPQFFGFVTFAIAGVAVCHRHPFDQPEAE
                     QELADGYHIEYSGMKFGLFFVGEYIGIVTVSALMVTLFFGGWHGPFLPPFVWFALKTA
                     FFMMMFILIRASLPRPRYDQVMSFGWKVCLPLTLINLLVTAAVILWQAQ"
     gene            complement(25431..28157)
                     /gene="nuoG"
                     /locus_tag="OPV72_000876"
     CDS             complement(25431..28157)
                     /gene="nuoG"
                     /locus_tag="OPV72_000876"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311194.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoG"
                     /protein_id="HCR9913248.1"
                     /translation="MATIHVDGKEYEVNGADNLLQACLSLGLDIPYFCWHPALGSVGA
                     CRQCAVKQYQNAEDTRGRLVMSCMTPATDGTFISIDDEEAKQFRESVVEWLMTNHPHD
                     CPVCEEGGNCHLQDMTVMTGHSFRRYRFTKRTHRNQDLGPFISHEMNRCIACYRCVRY
                     YKDYADGTDLGVYGAHDNVYFGRPEDGTLESEFSGNLVEICPTGVFTDKTHSERYNRK
                     WDMQFAPSICQQCSIGCNISPGERYGELRRIENRYNGTVNHYFLCDRGRFGYGYVNLK
                     DRPRQPVQRRGDDFITLNAEQAMQGAADILRQSKKVIGIGSPRASIESNFALRELVGA
                     ENFYTGIARGEQERLQLALKVLREGGIYTPALREIESYDAVLVLGEDVTQTGARVALA
                     VRQAVKGKAREMAAAQKVADWQIAAILNIGQRAKHPLFVTNVDDTRLDDIAAWTYRAP
                     VEDQARLGFAIAHALDNTAPAVDGIDSDLQNKIDVIVQALAGAKKPLIISGTNAGSSE
                     VIQAAANVAKALKGRGADVGITMIARSVNSMGLGMMGGGSLDDALGELETGSADAVVV
                     LENDLHRHASATRVNAALAKAPLVMVVDHQRTAIMENAHLVLSAASFAESDGTVINNE
                     GRAQRFFQVYDPAYYDNKTIMLESWRWLHSLHSTVENREVDWTQLDHVIDAVIAAMPQ
                     FAGIKDAAPDATFRIRGQKLAREPHRYSGRTAMRANISVHEPRQPQDKDTMFAFSMEG
                     NNQPTAPRSEIPFAWAPGWNSPQAWNKFQDEVGGKLRHGDPGVRLIEATEGGLDYFTT
                     VPASFQAQDGQWRIAPYYHLFGSDELSQRSPVFQSRMPQPYIKLNPADAAKLGVNAGT
                     RVSFSYDGNTVTLPVEISEGLAAGQVGLPMGMPGIAPVLAGARLEDLREAQQ"
     gene            complement(28188..29525)
                     /gene="nuoF"
                     /locus_tag="OPV72_000877"
     CDS             complement(28188..29525)
                     /gene="nuoF"
                     /locus_tag="OPV72_000877"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoF"
                     /protein_id="HCR9913249.1"
                     /translation="MKNVIRTPETHPLTWRLRDDKQPVWLDEYRSKNGYEGARKALTG
                     LSPDEIVSQVKDAGLKGRGGAGFSTGLKWSLMPKDESMNIRYLLCNADEMEPGTYKDR
                     LLMEQLPHLLVEGMLISAFALKAYRGYIFLRGEYIEAAVHLRRAIAEATEAGLLGKNI
                     MGTGFDFELFVHTGAGRYICGEETALINSLEGRRANPRSKPPFPATSGVWGKPTCVNN
                     VETLCNVPAILANGVEWYQNISKSKDAGTKLMGFSGRVKNPGLWELPFGTIAREILED
                     YAGGMRDGLKFKAWQPGGAGTDFLTEAHLDLPMEFESIGKAGSRLGTALAMAVDHEIG
                     MVSLVRNLEEFFARESCGWCTPCRDGLPWSVKILRALERGEGQPGDIETLEQLCRFLG
                     PGKTFCAHAPGAVEPLQSAIKYFREEFEAGIKQPFSNTHLINGIQPNLLKERW"
     gene            complement(29522..30022)
                     /gene="nuoE"
                     /locus_tag="OPV72_000878"
     CDS             complement(29522..30022)
                     /gene="nuoE"
                     /locus_tag="OPV72_000878"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoE"
                     /protein_id="HCR9913250.1"
                     /translation="MHENQQPQTEAFELSAAEREAIEHEKHHYEDPRAASIEALKIVQ
                     KQRGWVPDGAIYAIADVLGIPASDVEGVATFYSQIFRQPVGRHVIRYCDSVVCHITGY
                     QGIQAALEKNLNIKPGQTTFDGRFTLLPTCCLGNCDKGPNMMIDEDTHSHLTPEAIPE
                     LLERYK"
     gene            complement(30025..31827)
                     /gene="nuoC"
                     /locus_tag="OPV72_000879"
     CDS             complement(30025..31827)
                     /gene="nuoC"
                     /locus_tag="OPV72_000879"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit C/D"
                     /protein_id="HCR9913251.1"
                     /translation="MVNNMTDLTAQDAAWSTRDHLDDPVIGELRNRFGPDAFTVQATR
                     TGIPVVWVKREQLLEVGDFLKKLPKPYVMLFDLHGMDERLRTHRDGLPAADFSVFYHL
                     ISIERNRDIMLKVALSENDLRVPTFTKLFPNANWYERETWEMFGIDIEGHPHLTRIMM
                     PQTWEGHPLRKDYPARATEFDPFELTKAKQDLEMEALTFKPEDWGMKRGTDNEDFMFL
                     NLGPNHPSAHGAFRIILQLDGEEIVDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRIE
                     YLGGCVNEMPYVLAVEKLAGITVPDRVNVIRVMLSELFRINSHLLYISTFIQDVGAMT
                     PVFFAFTDRQKIYDLVEAITGFRMHPAWFRIGGVAHDLPRGWDRLLREFLEWMPKRLD
                     SYEKAALRNTILKGRSQGVAAYGAKEALEWGTTGAGLRATGIDFDVRKWRPYSGYENF
                     DFEVPVGGGVSDCYTRVMLKVEELRQSLRILQQCLDNMPEGPFKADHPLTTPPPKERT
                     LQHIETLITHFLQVSWGPVMPAQESFQMVEATKGINSYYLTSDGSTMSYRTRVRTPSF
                     AHLQQIPSAIRGSLVSDLIVYLGSIDFVMSDVDR"
     gene            complement(31914..32576)
                     /gene="nuoB"
                     /locus_tag="OPV72_000880"
     CDS             complement(31914..32576)
                     /gene="nuoB"
                     /locus_tag="OPV72_000880"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoB"
                     /protein_id="HCR9913252.1"
                     /translation="MDYTLTRIDPNGENDRYPLQKQEIVTDPLEQEVNKNVFMGKLHD
                     MVNWGRKNSIWPYNFGLSCCYVEMVTSFTAVHDVARFGAEVLRASPRQADLMVVAGTC
                     FTKMAPVIQRLYDQMLEPKWVISMGACANSGGMYDIYSVVQGVDKFIPVDVYIPGCPP
                     RPEAYMQALMLLQESIGKERRPLSWVVGDQGVYRANMQPERERKRGERIAVTNLRTPD
                     EI"
     gene            complement(32592..33035)
                     /gene="nuoA"
                     /locus_tag="OPV72_000881"
     CDS             complement(32592..33035)
                     /gene="nuoA"
                     /locus_tag="OPV72_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoA"
                     /protein_id="HCR9913253.1"
                     /translation="MSMSTSTEVIAHHWAFAIFLIVAIGLCCLMLVGGWFLGGRARAR
                     HKNVPFESGIDSVGTARLRLSAKFYLVAMFFVIFDVEALYLFAWSTSIRESGWVGFVE
                     AAIFIFVLLAGLVYLARIGALDWTPARSRRERMNPETNSIANRQR"
BASE COUNT         7506 a         9689 c         9002 g         7044 t
ORIGIN      
        1 tgcgttaaaa aataagccct tttctattgc cgaaatattt gaaaagcggc tttcaatggc
       61 tgaaggaaaa atgatgtcgg actttttgcc tttctcccgt ccggcgatgg gcgcggaaga
      121 gctcgctgcc gttaagaccg tactggactc aggttggata acaaccggcc cgaaaaatca
      181 ggaactggaa gcggcgtttt gtcggctaac aggcaatcaa tatgccgttg ccgtcagttc
      241 agccactgcc ggtatgcaca tcgcgttgat ggcgctgggt attggtgaag gcgacgaggt
      301 cattacaccg tcaatgacgt gggtttctac gctaaatatg atcgttttac tcggcgcgac
      361 ccccgtcatg gtcgatgtcg atcgcgatac gctgatggtc acgcctgaac atatcgaagc
      421 cgcgattacg ccacaaacca aagcaattat ccccgtccac tacgctggcg cgcccgccga
      481 tctggacgct atttacgctc ttggcgcgcg ttatggcatt ccggtgattg aagacgcggc
      541 gcacgcgaca ggaaccagct acaaaggtcg ccacattggc gcccggggca ccgcgatttt
      601 ctccttccac gccattaaga acattacctg cgctgaaggc ggtatcgtcg tcacggataa
      661 cccgcaattc gccgataaac tgcgcagtct caagtttcac gggcttggcg ttgatgcctg
      721 ggatcgacag agcggaggac gcgcgccaca agcggaagtc ctggcgccgg gctacaaata
      781 taatttgccc gacttcaacg ccgctatcgc gcttgcccag ttacagaaac tggatgcgct
      841 taacgctcgc cgcgccgcca tcgcagcgca gtaccatcag gcaatggcag accttccttt
      901 tcagcctctg agccttccgc cgtgggagca tattcacgcc tggcatttat tcattatccg
      961 ggtcgatgaa gcccgctgcg gtattacccg ggatgctctg atggcatcgc tgaaaacgaa
     1021 aggcatcggc acagggctgc atttccgcgc cgcgcatacg caaaaatatt atcgcgaacg
     1081 tttcccaacg ctcacgctgc ctgacaccga gtggaacagc gagcggatct gctcactgcc
     1141 gctcttcccg gacatgaccg agagtgactt tgatcgggtc attaccgccc ttcatcagat
     1201 agcaggacaa taagcatgtt tgacgccgcc cccataaaaa aagtctcggt ggttattcct
     1261 gtctataacg aacaggaaag cctgccggaa ttgataagac gcaccaccac cgcctgcgag
     1321 agtctgggca aagcgtggga gattttattg atagatgatg gtagcagcga tagctcggcg
     1381 gagctgatgg ttaaggcgtc ccaggaggcc gatagccata tcatctctat tttactcaac
     1441 cgtaactacg gtcaacatgc agcgattatg gcggggttta gccatgtaag cggcgatctc
     1501 atcattacgc tggatgccga tctgcaaaac ccgccggaag agatcccgcg cctggtggcg
     1561 aaagccgatg aagggttcga tgtggtaggc accgtgcgac agaaccgaca ggacagcctg
     1621 tttcgcaaat cggcgtcaaa aatcattaat ctgctgatcc agcgcacaac gggcaaagcg
     1681 atgggcgatt acggctgcat gttacgcgcc tatcgccgcc ctattatcga taccatgttg
     1741 cgctgccatg aacgcagcac ctttatccct attctggcca acattttcgc tcgtcgggct
     1801 accgaaatcc cggtgcatca cgctgaacgt gaatttggcg actctaaata cagttttatg
     1861 cgtctcatta acctgatgta tgacctggtg acctgcctga cgacgacgcc tctgcgcctg
     1921 ttgagtctgc tgggcagtgt tatcgccatc ggcgggttta gcctgtcggt attgcttatt
     1981 gtacttcgcc tggcactggg accgcagtgg gcggcggaag gcgtatttat gctctttgcc
     2041 gttctgttta ccttcatcgg cgcgcaattc atcggtatgg gactgctggg cgaatacatc
     2101 ggtcgcattt ataacgatgt ccgcgcccgc ccccgctatt ttgttcaaca agttatctac
     2161 ccggaaagca cgtcgtttac tgaggaaagt caccaatgaa agccgttatt tttgcctatc
     2221 acgatatggg atgtcagggc gtgcaggccg tactggatgc aggatatgag attgccgcaa
     2281 ttttcactca tgccgacaat cctgcggaaa acaccttttt tggctccgtc tcccggctgg
     2341 cggcaggatt agggattccg gtttatgcgc cggataacgt aaaccatcct atctgggtcg
     2401 accgcatcgc tgaacttgcg ccagatatta ttttttcgtt ctattaccgc aacctgttaa
     2461 gcgaagaaat tctgcacctc gccccggctg gcgcgttcaa tctgcacggt tctctattgc
     2521 cagcctatcg tggccgtgcg ccgctaaact gggttctggt taacggcgaa agcgaaacgg
     2581 gcgtaacgct gcatcgtatg gtcaaacgtg ccgacgccgg agagattgtc gccagtcaac
     2641 gcgtcgctat tgcgcaggac gatgttgcgc ttaccctgca tcataagcta tgtcaggccg
     2701 cgcgccagtt acttaatagc atcctgccca ccatgaaatg cggcaatata ccttctgttc
     2761 ctcagcgtga gtctgacgct acgtattatg gtcgccgcag gccggaagat ggccttatcg
     2821 actggcacaa accggtttcc acggtgcata acctggtgcg ggcggtagcc gccccctggc
     2881 ccggcgcgtt cagctataac ggctcgcaaa aattcactat ctggtcttcc cgaatttgtc
     2941 cggatgcgca aggcgcgctt cccggctcgg taatttcggt ctctccgctg cgggtcgcct
     3001 gcgccgatgg cgcgctggag attattaccg gccaggccgg agacggcatt actgtacagg
     3061 gctcgcagct tgcacagacg cttggtctgg tggcgggcgc gtgtttgaac cgtccaccag
     3121 cgaccagcgg taaacgtcgc attcgcgttc tcatcctcgg cgtcaacggt tttatcggca
     3181 atcatttgac cgaacggtta ctggatgaag agaattacga ggtctacggt atggatatcg
     3241 gcagcaacgc cattagccga ttcctgctcc accctcgctt tcatttcgtg gagggagata
     3301 tcagcatcca ctcagaatgg atcgaatatc atgtcaaaaa atgcgatgtc gtactgccgc
     3361 tggtagcaat tgcaaccccg attgaataca cccgcaaccc gctgcgcgtc tttgaacttg
     3421 attttgaaga aaacctgcgg attatccgtt attgcgtgaa ataccgtaaa cgcgtggttt
     3481 tcccgtctac ctctgaagtg tacggcatgt gtacggacgc ctcttttgac gaagacaaat
     3541 cgaatctgat cgtcgggccg gtgaataagc cgcgctggat ttactccgtt tccaaacagc
     3601 ttctcgaccg ggtgatttgg gcttatggcg aaaaagaggg attgcgcttc acgcttttcc
     3661 gtccctttaa ctggatgggg ccgcggctgg atagcctgaa cgcggcgcgt atcggcagtt
     3721 cacgcgcgat aacgcagttg attctgaacc tggtagaagg gacgccgatc aagcttatcg
     3781 acggcggtca gcagaagcgc tgtttcaccg atattcgtga cgggatcgaa gcattattcc
     3841 gcattattgt gaatgagggc gatcggtgcg atggcaaaat cattaatatc ggcaaccctg
     3901 acaacgaagc cagtattcag gaactggcga cgctgttgct cgacagtttt gataagcatc
     3961 cgctgcgctg ccatttccca ccatttgccg gtttccaggt cgtcgaaagc cgtagttatt
     4021 acggcaaggg ttatcaggat gtcgcacacc ggaaacccag tatcgacaat gccaggcgct
     4081 gtctggactg ggagccgtct attgcgatgc gtgatacggt tgaagaaacg ctggacttct
     4141 ttctgcgtag cgtcgatatc gcggaacgcg catcatgacg aaagtcggtt tacgcattga
     4201 cgttgatacc ttgcgaggaa cgcgtgaagg tgttccccgg ctgctggcga cattgcatcg
     4261 ccacggcgtt caggccagct ttttcttcag cgtcgggccg gacaatatgg gacgccatct
     4321 ttggcgtctg ataaaaccgc gatttttatg gaaaatgcta cgttcaaacg ccgcctcgct
     4381 ctacggttgg gatatcctgc tggccggcac cgcctggccg ggaaaaaata tcggcaacgc
     4441 taatgccggg attattcgtg aaacggcaac ataccatgag acgggactac atgcctggga
     4501 tcaccatgcg tggcagactc acagcggcca ctggagtatc cgccagcttg aagaagatat
     4561 tgcgcgcggc ataacggcgc ttgaggccat tatcggaaaa cccgtcacct gctcagccgc
     4621 ggccggctgg cgagcggatg ggcgcgttgt tcgtgcgaaa gaaccgttca acctgaggta
     4681 taacagcgat tgccgtggaa ccaccttatt ccgtccgcta ctgatgccgg gccagacagg
     4741 gacgccgcaa atcccggtca ccttacccac gtgggatgag gttatcggcc ccgccgttca
     4801 ggcgcagtcg ttcaatacct ggattatttc ccgtatgttg caggacaaag gcacgccggt
     4861 atataccatc catgcggaag tcgaaggtat tgtccatcag ccgctgtttg aagatttgct
     4921 cgttcgtgca cgcgatgcgg ggatcacctt ttgtcctctg ggcgaactgc tgccggcatc
     4981 gcctgagtct ctgccgttgg ggcaaattgt acgtggacac atccctggcc gtgaaggttg
     5041 gctggggtgt caacaggcag tgagcgcctc atgatgaaat cgatacgcta ttatctggct
     5101 ttcgccgcgt ttatcgcgct ctactatgtt attcctgtca acagccgcct gctctggcag
     5161 ccggatgaaa cgcgctatgc cgaaataagt cgggagatgc tggcgtctgg cgactggatc
     5221 gtgccgcatt ttctgggatt acgttatttt gaaaaaccga tagccggtta ctggataaac
     5281 agtctgggtc agtggctttt tggcgctacc aattttggcg tgcgggccgg cgctatttta
     5341 acgacattgc tggccgcagc gctggtggcg tggctgacgt tccgcttatg gcgggataaa
     5401 cgtaccgcgt tgctcgcctc cgtgatcttt ctctccctct ttgccgttta cagtatcggg
     5461 acgtatgcgg tactcgaccc gatgatcgcg ctttggctta cggccgggat gtgttgtttc
     5521 tggcagggga tgcaggccac gacccgaacg ggcaagattg ggatgttttt gctactgggc
     5581 gcaacctgcg gtctgggtgt attaactaaa gggttcctcg ccctggccgt accggtggtg
     5641 agcgtgctgc cgtgggttat tgttcagaaa cgctggaagg actttttgct ttacggctgg
     5701 ctggcggtct tgagctgctt tgtggttgtc cttccctggg cgatcgccat tgcgcgacgc
     5761 gaagccgatt tctggcatta ctttttctgg gtggagcata tccagcgatt cgccatgagc
     5821 gatgcccagc ataaagcccc tttctggtac tatctgccgg tgctgctcgc gggaagttta
     5881 ccgtggctgg ggttactgcc tggcgcgctt aaactgggct ggcgcgagcg aaacggcgca
     5941 ttctatttgc tcggatggac gatcatgccg cttctctttt tcagcattgc gaaagggaaa
     6001 ctgcccacct atgttctttc ctgtttcgca ccgatagcga tactcatggc gcgcttcgtc
     6061 ctgcataacg taaaagaagg cgtcgccgcg ctacgtgtca acggcgggat caacctggtg
     6121 ttcgggataa tcgggatcgt cgcggcgttt gtcgtctcct catggggccc gctgaaatcg
     6181 ccggtgtgga cgcatatcga aacctataaa gtgttttgcg tctggggcgt ctttactgtt
     6241 tgggcgtttg tgggctggta tagcctctgt catagcccaa aatacctatt acccgcgttt
     6301 tgtccgctgg gactggcgct gctgttcggc ttttccgtcc ccgacagggt gatggagtcc
     6361 aaacagccac agttttttgt cgaaatgacc caggcgcctt tggcatcaag ccgctatatt
     6421 cttgccgaca gcgtgggcgt cgccgccggg ctggcctgga gtctgaaacg agacgatatt
     6481 atgctctacg gacacgcggg cgaactcagg tatggtctta gctatcctga tgtacagaat
     6541 aaattcgtta aagccgacga ttttaacgcc tggctcaacc aacatcgtca ggagggcatt
     6601 attacgctag tactttcaat agacaaagac gaagacatca gcgcactttc ccttccccct
     6661 gcggacaatg ttgattatca ggggcgtctg gtgttaattc agtatcggcc taaatgatcg
     6721 gcatcgttct ggtgcttgcc agtctgctca gcgttggcgg tcagctctgc cagaagcaag
     6781 cgacacggcc attgacgacg ggcggacgcc gccgtcactt gatgctgtgg ctgggcctgg
     6841 cgctgatatg catgggtgca gcgatggtgc tgtggctgct ggtgctacaa accctgccgg
     6901 tgggaattgc ttacccgatg ttgagtctga attttgtctg ggtcacgctg gcggcctgga
     6961 aaatctggca tgaacaggtt ctgccccgcc actggttggg cgtcgcatta attatcagcg
     7021 gcattatcat tctggggagt gcggcataat gggcgtaatg tggggactga taagcgttgc
     7081 gattgcctcc ctcgcccagt tgagtttagg attcgccatg atgcgactgc catcgatagc
     7141 gcatccactg gcgtttattt ccgggctggg cgcatttaat gccgcgaccc tggcgctatt
     7201 cgccggtttg gcgggatatc tggtttccgt cttctgctgg cagaaaacat tacacatgct
     7261 cgcgctcagc aaagcctatg cgctgctgag tctcagttat gtgcttgtct gggtagcctc
     7321 aatgttgtta cccggtttgc aaggcgcttt cagcctaaaa gcgatgctcg gcgtattgtg
     7381 cattatggcg ggggtaatgc tgatttttct gcccgccaga tcataatggc ttgcgcgtca
     7441 accgctgcca ttcgtcgcag gaataacagc gtgcatcaac gatttttaag gtctggtgtt
     7501 tttcccgatt aatacaatac tgcgcatcct gtaaaggcga caggatatcg ccgggactca
     7561 gtaatatcat ggaattcgcc tcggcgatca tttttagcga accgccgcta tcgcacagca
     7621 ccagaacatg gcacgccctc tttttgacat aatgcgattt cttaaccaac cattccatag
     7681 cgcccccgtt tcacgctgat tgttcataac acgttacaca tcaacggata aacaaaacgg
     7741 caatagcgat ggaatggttg tatattaacc taacattaat ttttacagat cttacacacc
     7801 cactgctgga gcgcacggcg agatatttta atccctccgt ttttcagttc tgacggcagc
     7861 gtcaaccagc gaaccggctg ttgaaaacgc gccagcttat cgcgaaccca ttcagcgagg
     7921 ttcacgtctc cggcctgcga tgcatactcc acaaccgcaa cgggacgatg gccaaactct
     7981 ttatcttcta ccggcacgac aaaggcttgt tgcaccagcg gatgcgcgtt aataacgcgt
     8041 tcgacttcct ccggctgaat gccttcgccg ccgctaaaga acaagttgtc cagccgcccg
     8101 gcgatggtta gcctgccgtg gttcagctcg ccgcgatcgc gcgtggcaaa ccagccttcg
     8161 tcattaacca gcgggatcag tttgccatca cgccagtaac cttccgccat actggcggcg
     8221 cgcagccaga cttcattatc gacgattctg atctctctgc cgggaagcgg cgcgcccaca
     8281 tcatccgaac catcggcctc tttggcgcat accgtagacg cgaactccgt gagcccatac
     8341 ccgcaccagc agcgaatccc ttgtttgctg gcctggtcgg tgagttcaac cggaatcacc
     8401 gcgccgccga gcaaaacggc tttcagcgtc accgccgccc gattcgccaa cagccgccac
     8461 agctgcgtcg gcaccaacga agcatgagta caacctgcca gcatctgctc cagcggttgc
     8521 ttatcgcgta ccgtcatgcg cgccccggcg aagagccaac gccacataat accctgcccg
     8581 gatacatgaa acagcggcag cgatagcagc cagtcatcct gagggccaaa cggcattagc
     8641 gaaagcaccc cctgcgcgct ggcaagatgc gcctggcacg tatgtacagc cgcttttggc
     8701 aatcctgtgg aacccgatgt cagcgtcatg gaaaccagac gctgcggttg ccaggccaca
     8761 gcatacgcca ctgtactttt ccgcaactgc aacacggtta atccggaaaa cgcgttttcg
     8821 ccttccagtg tcagcgcaaa acgcagcgtt aacttcggca ccagcgcctc cagcaacgtc
     8881 tggggcaact gcgggttgac gggcagaacc cgcgcgccgc actgcatcag cgcaagccat
     8941 gccaacagag tgcgcggctg attcccggcg cgcagcagga caccgtcgcc ctcccgtacg
     9001 ccctgcgcgg caaacccgcc cgccagcgca tcaatacgct cacagagggc gcgccagctt
     9061 agcacttcat cgttcaggcg cagagcgggc gcctgactgc gaacctgacg ccagtggcgc
     9121 cacggccagt ccgtgaatgt cataacagtc gttccagctc atcacgcttc agacaaggca
     9181 acgcgttacc aggccagggg cgaacctgtt gcgcctgcat cagatgcaag gtatccagtc
     9241 cgggcagcgt tcccggcgtc aaccaggcgg caatccgcgc cagttgcgtc aggccgaggc
     9301 tggactcgat cgaagagctg atgaccgccg tcagtcccaa cgcatgggcg gcagcgactt
     9361 gctcacgcac tttatcaagc gatccggtca gcgtaggttt gataaccaca gccctgacgc
     9421 cctcttcggc ttcaaaggtg aaatccgctt cgcgcagact ttcgtcccag gcaatcgcga
     9481 tgccggtttc acgggcaaag gcgcgggaat catcccgcgt cttacacggt tcttcgagaa
     9541 aggcgatacg agcgcggtaa tccggattaa catactttgc gaactgttgg gcttttagcg
     9601 gcgtccaggc gcgattcgca tccagacgca gatgcagatc cgggatcgcc tccagcagca
     9661 aattaaccac catgccgtcg cgtaccgctt catagagacc cactttgacc ttagcgattt
     9721 tctcgccggg catatcggca agccgcagta ccaaatcgtc aggatcgcca gtgcataacg
     9781 gcgcggcgcg atagtccgcc gcctccggca agacgccagt cagttccgcc agcgcgcagc
     9841 ttgcgccaaa cgcgaccgaa ggcatctccg gtaatccctc gctcccctga agccagtcat
     9901 tcacccatgt caggagcgcc gtctgcgcct cttcccacgt ttcctgactg aagcccggca
     9961 gcggggagat ctctccccac ccttcacgct cgccgtcacg cagacaaaca tacagcccgt
    10021 cgcgagtttt taaccgcctg tcgcgcagaa ccacccccgc gtccatgggg atctgccagc
    10081 ggtatacctg cgcgctacgc attatgggtt ccgtttgaat ttgctgaagt caggctgacg
    10141 cttctggtta aaggcgttac ggccttcctg cccttcttcc gtcatgtaga acagcatggt
    10201 agcgttgccg gccagctcct gcagcccggc ctgaccgtca caatcagcat tcagcgccgc
    10261 tttcaggcaa cgcagcgcca tcggactgtt ttgcaacatt tcgcggcacc agcgcacggt
    10321 ctctttttcc agatccgcca gcggaacgac ggtgttaacc agccccatat ccagcgcctg
    10381 ttgcgcatcg tactggcggc acaggaacca gatttcacgc gctttcttct gaccaacgat
    10441 acgcgccata tacgaagcgc cccagccgcc gtcaaaggag ccgactttcg gaccggtctg
    10501 gccgaagatg gcgttttcgg ccgcgatggt caggtcgcac atcatgtgca gcacatgacc
    10561 accgccgatg gagtaacccg cgaccatcgc gacaaccggt tttggacagg tgcgaatctg
    10621 gcgctggaag tccagcacat tcaggtgatg cacgccggag tcatcctgat aaccgccgta
    10681 atcgccgcgc accttctggt cgccgcccgc gcaaaacgct ttatcgcctt cgccggtcag
    10741 aataatcacg cccacgttgt cgtcgtaacg ggcatccgcc agcgcctgaa tcatctcttt
    10801 gacggtcaac ggacgaaatg cattgcgcac ctgcggacga ttaatggtga tttttgcaat
    10861 accgtcggtg gatttttcat aacgaatgtc ggtgtaaccc tccgagcagt cgtgccattc
    10921 taccggtgcg taaagcattg tttcatcagg atagatcata gtgtgtcctt tagtcagaga
    10981 cgcagaatct gagccagact gtctaccacg ccagcggggt tttcccggtg cgcgttgtgt
    11041 ccggcgttac gaatgacatg gcatgtcgcc gccacttcct gcgccagggc gcggaatttg
    11101 ctgtcgcgtt cgccacataa ataataaaac ggaaatgcca gcgcgttaag cacctcgcgt
    11161 aaatccggct ggacggcaag cgatgtcgcc tccagcatcg cagccagcgt ttcgccgtta
    11221 ttctggctac gcagcgccgt tagcgcctgc ctttgctgcg ccgtcagcga ggcgaacacc
    11281 ggctgctgat accagtcgtg aaaaacctca gtcaagggtt catgacgaaa acgctctgcc
    11341 cagcgcccgt cggacaatcg tctttcagcg cgcgcctgtt cattttgcag ccccggatga
    11401 ccgccttcga ccaccaggcc gcacaggccg ggtattccct ggcaggctgc catcatcgcc
    11461 acacggccgc caagggagta tcccaccaac caaaacttta gtatgttgta actaattaac
    11521 gtggcgcgca gtaatctgat gacatcggca aagccgccga ccggaatagc cgcagatccg
    11581 ccatgtcctg gtaagtcaat ataaagccgc gaacagccgt gaaactgttc gccaaccggc
    11641 tgccattcgc ggcaatcgcc agaaaaaccg tgcaggaaaa ccagcgaggg cgtcccaggc
    11701 tgtccgggca tgtgctgcgc gtgcaacatc atagatggct tacctgagcc aaaagttgct
    11761 gcagcgtctg cgcgccatcc gtatcgttta ccaccagctc aatcaccgtt gtcgccgggg
    11821 ttcgccacgc gccagccagc gcagactcca gttcttccca gttttccggg cgatgatagc
    11881 gcaggttaaa catggcggcc gcatggtcaa aatggacgtt ttgcggcatc agataaaagc
    11941 gctcacgctt actttgcggc gtcggcagca gggaaaagat ctgcccgccg ttattgttga
    12001 ccacaatcaa cacaaacggc gcggatacct gacgtagtaa cgccagcgcg ttaagatcgt
    12061 acagcgcgga taaatcaccg acgatagcca acgtcgattt ggcgctggcg cgctgcacgc
    12121 ccgccgctgt ggaaagcagg ccgtcaatgc cgctcgcccc gcgattgctg tataccggat
    12181 agccggccgg caactgtgac agcgcgtcga tcagacgcac caccagacta ttgcccacga
    12241 acaattgccc ctgctccggc agatagtcgc ggatacggtg cgccagctgc gcttcgccaa
    12301 aggtgtctcg ctgcgcgacc acccgttgcc acgccagttc cgccagacgc gggatctcta
    12361 cacaccacgg tttacgtttt tccgccggat gcagttccag ccaatcggcg attttcgcta
    12421 ccagtctgcg tccacgatgg tgcgccgggt ccagacgacc ttcaatattg tcgattaccc
    12481 agtactcttc cggcacgcag gttgcctgcc attgcagtaa gcgttttccg gtaaggctac
    12541 tgccaagctg gacgacaatc tgcgcctgct gcagttcggt caccgctttg gcgttgccga
    12601 gccacaggtc ggcgcacggc agcggctgcc cggtttgcga caatacgtcg ccaattaatg
    12661 gccatcccag agtttgcgcc cactgcgcca cttttttgcc ttcttccgcg ctcatacgcc
    12721 cggcgacaac gacaccgcgt ttttgtcgcc agaagaacca gtcgcgctgt ttgtcgcttg
    12781 ccagtcgacg cgcttcgcgc agccagggtt tttcatcctg ccaccagtcg ccgagacgct
    12841 gctgccagac cagaccggtg tcattcatat cgccatacag cggttcggca aaaggacagt
    12901 taatgtgcag cgcgcccgca tgaagcatgg cgagcgcatt gtcgatggtc gacaccagcc
    12961 agcgcgccgg aatatcctgc gtgggacgcg gcaacgacag agtttgggag gggtgcgagg
    13021 caaacatccc cgcctgacgg atcgcctggt tggcgccgca gtcaatcagc tccggcgggc
    13081 gatcggcggt aagtaaaatg agcttctcgc ccgtcagacc cgcctcaatc agcgccggat
    13141 agaggttcgc cacggcggta cctgaagtga caataacggc aaccggctgt tggctgactt
    13201 tcgccagccc taacgccaaa tgaccaagcc cacgctcatc aaagtgcgta tggtgaataa
    13261 aagcaggatt ctctgccgcc gccaacgtga gcggcgtgga acgggaacca ggggcgatac
    13321 aaacatgcct gacgccatga cgggttaagg cttccaggat gaccgccgcc cagcgccggt
    13381 taaatgcact tactgacatg agtttgtccg gtatcaatca ttgggactaa gtataaagag
    13441 ctgcaaaaat ggattattga tatgggtcgg gaatatgtga ctcattacgc gtccatctgc
    13501 aataaggtac gtaacccggc cgctttatta tctatttcct gccattcctg ttccggatcg
    13561 gagccgcgga cgattcccgc gccggcatac aaccgcacca cattggccgt cactttggct
    13621 gaacgtaacg tcacgcaaaa ctcactttgc cgcgtggaga gatagcctgc cgacccggca
    13681 taccattcac gttcgaacgg ctcatgttgt tctataaaac aacgcgcggg ttcacgaggg
    13741 atcccggcga ccgctgcggt aggctgtaac tggtgcaggc agagcgtgtc gtccgcctga
    13801 ttaagcgccg tccagataca gcggcgcaaa tgctgtacct tgcgcagtct gagcacctgc
    13861 ggcggcagca catccagcga gtgggtgcag ttttgcagtc gctggcagat gtcttcgaca
    13921 accagcatat tttctcgctg gtttttatcg tctttcatta accattcgcc aagctgccag
    13981 gctttatggt tatccggatg gttcgccacc gtcccggcca gcgcttcggt acgcagcgcc
    14041 gtttcacgac gccgccagag ccgctccggc gatgatccca gaaaggcggt atcggcggaa
    14101 aaggccataa aaaagtggta gcagttgaga tttaaacgac gactggacgc catcatcgcg
    14161 gcggcattga ccggacggga gaattgtaag tcggtggccc gcgccagcac aactttatca
    14221 aacgcctctt gcgcaatagt gtgggtggcc tgctgaatca gcttcaccca accgtctttg
    14281 tccggccagt gttgttcgct cgtgagcgaa aggcgcagcg ccggaacagg cttaataccg
    14341 accagagaag cgagaaacgc tttcgccagg cgcgcatcat cgcgtagcga aacgtcactg
    14401 tgcagatgta agcgtaaggt cgccgtacca ccgctacgtc gccactccag cctcggcagc
    14461 aataagtagc cctctttcgg ctcgaacgca ttcagccccc aaatacgcag gtcaggctgc
    14521 gcgtgctgac gtaaaaaccg ttgcgccaga tcgagcgatg aaaagacggt gatggccccg
    14581 agaacggcag cttcttcgtc gccattgcgc tgttgccagt agaattgcgg aaaggatgac
    14641 tggctggcca gccagctcaa tgcatcgaag gcatcgttta aagggaaagg cgcatcgaaa
    14701 acgcaaagcc ctggcgtcgc cggtatctct tgcgatagct gacgcgtcag attttccagc
    14761 gcagtagtaa tagaatgcac gcggcccctc cctgttaaaa accccacatt atacggggta
    14821 ctgccctaaa aaagcagtac ctcatttagg gagggttgca attctgttca gtggggggat
    14881 ttagcgccgc gccagcagca gtccaagcac cagtcctacc gccgcgccta cgccaatacc
    14941 ctgccagggt ttttcatgaa cgtagtcatc cgctttataa acggcctgct ttgcccggta
    15001 ataatagcta tccgacgcat ggcttacgcg gtttttcacc tcttccagcg cttgttccgc
    15061 gcgggctttc agctcaatgt atttttgatc ggcgggatcg cctgaggaac gtaaaacctc
    15121 ttccagcgtt tcgctgagca aagtcagatc atcatcaaca cgtgattcac caaattgata
    15181 tgacattctc attctccgtt gtgttaacac ctgctcctaa ctatagtcaa cggtttcggt
    15241 ttatgcctga tgaacctccc gcgccattcc ccggtgcgga atgccgtctt cgtcataaac
    15301 atcggtgacg ggaataaaac caaaccgcgc ataaaaaggt tgcagatgcg cctgcgcccc
    15361 cagatatagc ggcttatccg gccagtgccg cccacaagat tccagcgttt tcgccattaa
    15421 ttgctggccc agtttcgccc ctcgccaggc atcgctgacg atcacccggc caatgacaac
    15481 cgggtctgat tcgttatcac ttttcagaat cctcgcatac gccaccagct catcctgatg
    15541 ccagcccaga atatgccgat tgtcgccgac taaatcatcg ccatccacat ccaggtaagg
    15601 acagcgctgt tctaccacaa agaccgcgca gcgcaatttg agtaacgcgt aaagttgagg
    15661 aacagtaagt tcgctatggt ggagatcctg ccagtcaatc atgatgcgct cctgtgttgt
    15721 ggtaatcttg ggttaaacga taaccaaacg cgtatggaca agatggaatt aattttttta
    15781 ggtacgtccg caggcgttcc cacacgctca cgcaatgtaa cggcaatttt attacatctg
    15841 caacatccaa cgcagccggg agtatggctt tttgattgcg gcgaagggac acagcatcaa
    15901 atgcttaata ccgcgtttca tcccggtaag cttgagcgca tttttatcag ccatcttcac
    15961 ggcgatcatc tgtttggcct gccgggtctg ctatgcagcc ggtcgatggc ggggaatccc
    16021 catccgctaa ccgtatacgg gcctcaaggc gtgcgtgagt ttattgcaac cacactgcgc
    16081 cttagcggtt catggaccga ttttccgttg caaattgaag aaattagcgc tggcgatatt
    16141 cttgacgacg gtctgcgtaa agtgaccgca ttcaggctgg agcatccact ggagtgctac
    16201 ggatatcgcg ttgttgaaca tgacaagcct ggcgcgctga atgccagggc gttaaaagcc
    16261 gcaggcgtta cgcccggccc gctgtttcag gcgttgaagg caggaaaaac cgtcacgctt
    16321 gccgatggaa ggcagatcaa tggcgccgac taccttgctc ccgccgtggc cgggaaatca
    16381 gtggcgattt tcggcgatac cgcgccctgc gaggccgccc tcgcactggc gcagggtgtg
    16441 gatgtgatgg ttcatgaaac cacgctggat gcgtcaatgg aggagaaagc caacgctcgc
    16501 ggacacagct ccacccgtca aaccgcgacg ctggcgcggg aggctgccgt tggtcggctg
    16561 atcatgaccc acattagctc acgctatgac gataaaggct gtcagcgctt actggcggaa
    16621 tgccgcgcta ttttcccggc gacggagctg gcttacgatt tttctgtttt cccggtttag
    16681 cgctccattt tttgtcctca ttgccgataa cactaaaaaa ggcaggcttt cataatgagg
    16741 ttaggatgga caattttcag aaagatattg atgacagggc caatttaacc ctgtccaacc
    16801 gttttgaact gctgttattc cgtcttggta catcgctgca tgaacagaag tcagagctgt
    16861 tcggtatcaa tgtatttaag ctgcgcgaaa tcatacctat gcccgccttt acgcgcccgg
    16921 caggcatgaa agcgccgcta ttgggcatgg tcaatattcg ggatcaggtc attccggtga
    16981 ttgatttgcc agcggtagcg ggctgcaagc cggaaaccgg gctgaatatt ttgctgatca
    17041 ccgaatatgt gcgcagcgta caggcatttg ccgtcgagtc ggtggaaaat attatgcgtc
    17101 ttgactggca acaggtgcat accgccgaga aagccgtcaa cggtcgctac atcaccagta
    17161 ttgcctgcct ggatgacaac aaagaaacca acaacctggc gctggtgctc gacgttgagc
    17221 agatccttta tgatattgtc ccctccagcc acgatctgcg cgccaccaat ctgaagacca
    17281 ataaatttta tattaccccc ggcgcggttg ccattgtggc ggaagactcc aaagtcgcct
    17341 gcgcgatgct ggaaaaaggg ctgaacgcga tggaaattcc gcatcagatg catgtgaccg
    17401 gcaaggatgc ctgggagaga atccagcaac tggcgcagga agcggaggcc gaaggtaagc
    17461 caattagcga gaaaatcgcg ctagtcctga cagaccttga gatgccggag atggatggct
    17521 ttacgttaac gcgtaaaatt aaaaccgatg aacggctgaa aaagatcccg gttgttattc
    17581 actcttccct ttccggcagc gccaacgaag atcatgtgcg taaggtgaaa gccgacggct
    17641 acgtggccaa gtttgagatt aacgaactct cttcagtgat acaggaagtg atggaacgcg
    17701 cggcgcaaaa catcagcggc ccgctggtaa gccggcagtt gctaagttaa attccggtcg
    17761 ctgagacctt acaggccgga tggcggcgca agcgccttat ccggtctacc gtcctgagtc
    17821 attttaaaga atgacatcag gtaataaaaa acccgcttcg tgaagcgggt ttttcgtttt
    17881 tacttattgc ttacatcaac ggcgtcgcta actgcacaag gctaatcagc ggctgcggcc
    17941 agacgcccag taccaacacc agcaacgcgg agatcagcac cacgataccg cctgcgctgt
    18001 actgccagtt tgtcggcgcg tcgcgtcccg gttgctgcgg cgcgtgcagg tagagactca
    18061 ccgcaacgcg caggtagtag tacaaaccaa tcgcggaacc caccaccacg gcggcgacca
    18121 gccaccacag gctggcctga acgccgaccg ccagcacgta gaatttgccg ataaagccca
    18181 gcgtcattgg gatacctgcc agcgacagca tcatcaccgt catcaccgcg gcaagaaccg
    18241 gacggtgcca gaacagacca cggtaagagt acagggagtc ggcatccggg ccgcggaacg
    18301 ggctggacat caggctgacc acgccaaacg cgccgaggct gctgaacaga taaccggcca
    18361 gataaacgcc taccgcttcc atcgacatct cgccgctctg cagggcaatc agcgccacca
    18421 gcagatagcc gaggtgagag atagaagagt aaccgagcag acgtttgatg ttggtctggc
    18481 tcagcgccat caggttaccg aagatgatag aggcaaaggc gataatgccc agcaccacgc
    18541 gtaccgcttc gctgtcgcct accggcgcat acaggaacag acgcattacc acgccgaaga
    18601 tagcgatttt gctcgccgtc gccaggaagg tagaaaccgg cgcaggcgcg ccctggtaaa
    18661 cgtctggcgt ccacaggtgg aacggcacca gagagagttt aaagcccaga ccgacaatca
    18721 tcaggccaaa gcccgccagc agcaacggct cgtgcagcat accatcgccg aggctcttac
    18781 cgagcgcttc gaaagacagg ttgccggact gcgcatagac cagcgccatc ccgaacagca
    18841 ggaaagacga ggcggcggcg gagaggatgg tgtatttgat actggcttcc agcgagcgtt
    18901 tctggcggaa agcataacca atcaggccga acagcggcag tgagatcagt tcaataccga
    18961 ggaacagcgc cgccagatgg ttggcgttcg ccagcagaat tccccccagg ctggcgatta
    19021 acaccagcag gtagaactct tcctggttat cgttatagcc ttccagccac gggtaggcaa
    19081 aagtacaggt ggcgaggctc gccagcagca ccagcccggt gtagagcatc gcaaagccgt
    19141 caacgcgcat cagcggcgtg acgtccattg ccccggcctg gccgacaaac caaagcgaaa
    19201 ccagagcagc gttaagccca atgaccgaca gcgtggcatt gaggaagtga ttgcgtcgcc
    19261 acgcaatgga gagcatcaca accaccaccg tcaagccgac gatcagcagc ggtagcagcg
    19321 caatcaggtg ttgtggagtt attgtcatgg cgatttacgg ccttgtagta gtaacggaat
    19381 taacaaacca ctgctggatg ttgctcatcg cagaatgcga ggtatccaga atcggctgcg
    19441 gatagaagcc aagcagtacc agaagcacca ccagcaacag aatgataaac agctcgcgca
    19501 gcgacatccc tagcagttcc tggctggcaa tctggctctt cgctttacca aagtaagcgc
    19561 gatgcagcat cgccagcgag tatacagagg cgaataccag cccaaaggtc gagataacgg
    19621 taatcatcgg caccacctgg tagctgccga acagaatcat aaattcgccg acaaagttac
    19681 cggtgcccgg cataccgagc gtcgccaccg caaagaacat ggacagcgca ggcaaccact
    19741 tcatcttgcc ccacaggccg cccatcatac gcatgtcacg cgtatgcaga cgttcgtaca
    19801 actggccaca cagaatgaac agaccggctg cggacaaacc gtgtgcaatc atctgaatca
    19861 ccgcgccctg gtacgccagc tgactgccgg tgtagatagc gatcagcacg aagcccatgt
    19921 gggaaacgga ggtataggca atcaggcgct tgatgtcgta ttgggtaaag gccatccacg
    19981 cgccgtagaa aatgccgatg acgcccagcc acatggcgat gggcgcaaac tccgccgacg
    20041 cgttcgggaa caatggcagg gagaaacgca gcagaccgta agcggcggtt ttcagcaaga
    20101 tccccgccag gtcgacggaa ccggcggtcg gcgcctggga gtgcgcatcc ggcagccagc
    20161 catgcagcgg aaccaccggc attttcaccg cgaaggcgat gaagaagccc agcatcagca
    20221 gatattccac accgtgggac atcggggtat tcagcagctc ttcatagttg aaggtccaca
    20281 cgctggtcgc tttatagtgc acaaacacca gcgccaggat ggcaatcaac atcaccagac
    20341 cactcgcctg ggtgtaaatg aagaacttgg ttgccgccgt gatacgcgtt ttaccgtcag
    20401 aagctttgtg gccccacagc gctatcagga agtacatcgg caccagcatc atttcccaga
    20461 agaagaagaa caggaacatg tcgatggcca ggaacacgcc gataacgccg cctaagatcc
    20521 acatcaggtt gaggtggaag aagccctgat atttttcgat ttctcgccaa gagcaaagca
    20581 ccgccagaac gccgagcagg ccggtcagca ccaccattag cagcgacagt ccgtcgagcg
    20641 ccagatggat agagatgcca aaacgcggga tccacggcag gacaaattca gattgccact
    20701 gtggaatacc ggcggattgc gtcagtgagt agccgccctg caaccacaat tgcagaccga
    20761 gcgccagcgt cagttccatg gtaatcagcg ctatccagcg cggcactttc acgccaaagc
    20821 gttcggtctg ccagcacaga aagccgccga taaaggggat taatatcaac cagggtaata
    20881 acatagctaa gtatgtccct tatatttact cctgctcagg ctatctcact cgtcagccca
    20941 aatcctgcca gtgctcacac aaaacgcagc gcgttttgaa cgtccgtaag gacggccccg
    21001 taggggtgag cttcgcgaat catcctcacg tacttcagta cgctccggtt gctgtgcgct
    21061 ggcggtatcc ggtctgactt cgccgatgac gcctgtactt caggaacaga ttttcaacga
    21121 attctaaaaa ttatttttgg gtttgtaggc cggataagca ctgcgccatc cggcagtcgt
    21181 tcatccagcc aacaaactca acgcagtacc atcagcagcg ccagcaccac aaccgcgccg
    21241 atgctcatgg atgccacata ccagcgcaaa taaccgttct cgctcagtac caggcctttg
    21301 cctgcaaaac gggaaaggat agccggaatg ttcatcaacg cattaagcgg gtcgcgcttc
    21361 agcagccagg cgataccgag gaatggcttg acgaatactt tgtcgtacag ccagtcaaag
    21421 ccccaggcgt tataccacca ggtccccagc agatggcccg gcgcgctgtt ggcgatcgac
    21481 gtcaccagcg tacgtttacc cagccacagc catgcggcaa tcaggatgcc ggcaatcgcc
    21541 actacgccag aggtaatttc cagggtcaac acacgaccat gcgccagttc agttgtctgc
    21601 ggcagcaccc cctgcagagg cggcacaatc agcgcgccaa caaaggtaga cagaatcatc
    21661 aggacaatca gcggcagatg gtgggtaatc cccttccctg catgagcatg aatttgttct
    21721 ttaccgtgga atacgatgaa aatcatccgg aaggtgtaca gggaggtcat gaacgcgcca
    21781 accagacccg ccaccatcag attgatatga ccgttcgcca tcgcgccagc caggatctca
    21841 tccttactga agaagcccgc agtgaccagc ggcagcgccg acagcgccgc gccccccacc
    21901 aggaagcagg catacaccag tggaatggac ttacgcagac cgcccatctt aaagatgttc
    21961 tgttcgtgat ggcaggccaa aattaccgag ccggatgcca ggaacagcag cgctttaaag
    22021 aaggcgtgcg tcatcaggtg gaaaatcgcc gcatcccacg cctgcacgcc aagcgccagg
    22081 aacatgtagc caatctggct catggtggaa taggccagca cgcgtttgat gtcggtctgc
    22141 accagcgcgg cgaaacccgc catgaccagc gtaatcgccc cgataatgcc caccagatgc
    22201 agaatttccg gggtcatcag gaacaggcca tgcgtgcgtg cgatcaggta gacaccggcg
    22261 gtaaccatgg tggcggcgtg gatcagcgcg gagaccggcg tcggaccggc catcgcgtcg
    22321 gcaagccagg tctgcaacgg tagctgcgca gatttaccga ccgcgccgcc cagcagcatc
    22381 agcgtcgccc acatcagcat gttgttgccg tcagcaaagt gcgctggcgc cagctcgacc
    22441 atttcgcgga agttcagcgt gcccagttcg ttgtagagga tgaacagcgc gaaggcgagg
    22501 aatacgtcac cgacacgggt caccacgaag gctttcattg ccgccgcgcc attcttcgga
    22561 tcgctgtaat agaagccgat caacagataa gagcacaggc ccacgccttc ccagccgagg
    22621 tacatcaaca gcaggttatc ggacagcacc agaacaacca tgctggcgat aaacaggttg
    22681 gtataagcga agaagcggga gtagccctct tctccacgca tgtaccagga agcgaacatg
    22741 tggatcagga agccgacgcc ggtgaccaca gagagcatgg tcagcgacag gccgtccagc
    22801 accaggttaa aaccgatgtt gaagttaccg accgacatcc acgtccacag cggctggctg
    22861 aacgcctgtt tgccgttggc gaagaaatcc atcccgacaa acgctgtcac caacgccgcc
    22921 agaccaacgg agcccacgcc aatggtcgcg gagagatttt ccgaccagcg tccgcgagag
    22981 aacgccagca gtacaaagcc aatcaatggc agaataatgg ttaaggcaag catgttcatc
    23041 cacgcatctc acttactgaa tcgatgttca ggttctggcg acggcgatgg agttgcagca
    23101 acagcgcaag tccaatactc gcttccgcag ccgcaaggct gatggcgaga atgtacatca
    23161 cctgaccatc ggtctggccc cagtagctcc cggcgaccac aaaggccagc gcggaggcgt
    23221 taatcatgat ttccagcccg atcagcataa acagcagatt gcggcggata accagaccgg
    23281 ttaaacccag gacgaataaa atcgcagcga ggatcagtcc gtgtgttaag gggatcatgc
    23341 gcgctcctcc gtttttcttt tcgcgcggtc atcggcgcgg ttgcttagca cttcgcccgc
    23401 acgctcttca cgaccgacgt ggaacgccac caccaggcct gccagcagca gcatagacgc
    23461 cagttcgacc gccagaacat aaggcccgaa cagcgtaatg cccaccgctt tcgcgctaat
    23521 cggcgtgccg tcgatgccct ggtcgttaac gcccagaatg gcgtacacaa taaccgccag
    23581 cataatggcc gacaaaaccg ccggaccaat ccacacctgc ggcttcagcc actggcgttc
    23641 ctgttcgatt tcgctgccgc cgaggttgag catcatcacc acgaacacaa acagcaccat
    23701 aatggcaccc gcgtagacga taatttccag cgcaccggca aagtaagcgc ccagcgaaaa
    23761 gaacaccccg gaaatcgcca gtagcgatat caccagatac aacagcgcgt gtaccggatt
    23821 ggtatgggtg atcactcgca gggtcgcgag gatggctatc aggccacaga tataaaaagc
    23881 gaattccatt gccctctcct tacggtaaca ggctcttgac gtcgataggc ttggcttcgt
    23941 tctctgcttc gcctttatct ttgccgtcga ttgccatacc cgccatccgg tagaagttat
    24001 attccgggta tttgcccgga ccggaaatca gcagatcctc tttttcgtac accagatcct
    24061 gacgtttgta ttcgcccagt tcgaagtccg gggtcaactg aatcgccgtg gtcgggcacg
    24121 cttcttcgca caggccgcag aagatgcagc gtgagaagtt aatgcggaaa aattccggat
    24181 accagcggcc atctttggtc tccgcttttt gcagagagat acagcctacc ggacaggcta
    24241 ccgcgcacag gttacaggca acgcagcgct cttcaccgtc cgggtcgcgc gtgagcacga
    24301 tacggccacg gtaacggggc ggtaaataga ccggctcttc cggatacatc cgcgtttcgc
    24361 gtttcgcgaa cgcatgcagg ccgatcatcc agatactgcg tacctgagtg ccgaaaccta
    24421 ctaataattc ttttaaggtc atggtctttg tgtcccttat tgcgcctgcc acagaatgac
    24481 agccgccgtt accagcaagt tgatgagcgt cagcggcagg caaactttcc agccgaagga
    24541 cattacctgg tcataacgcg gacgcggtaa cgacgcacga atcaaaatga acatcatcat
    24601 gaagaacgcg gttttcagcg cgaaccagac gaatggcggt aagaacgggc catgccagcc
    24661 accgaagaac aacgttacca tcagcgcgga aacggtgacg atgccgatgt actcccccac
    24721 gaagaacaga ccgaatttca taccggaata ttcgatgtgg taaccgtccg ccagttcctg
    24781 ctcggcttcc ggctggtcaa acgggtgacg gtgacagacc gctacgcccg cgatggcgaa
    24841 agtaacaaac ccaaagaatt gcggaatcac gttccacaga tgcgcctggt tattgacgat
    24901 atcggtcata ttaaatgaac cggcctgcgc caccacgccc atcagggaaa gaccaaggaa
    24961 cacttcgtag ctcaccgtct gggcagacgc gcgcatcgcg cccagcagcg agtatttgtt
    25021 gttgctcgac caaccggcga acagtaccgc gtaaaccgcc agaccggcca tcatcaggga
    25081 gaacaaaatc ccgatgttta aatcggccac cacccagtta gggctaaccg gcacaatggc
    25141 gaaggagagc agcagcgaag taaacgcgat catcggcgcc agggtaaaga tgacgcgatc
    25201 cgagaatttc gggatccagt cttctttaaa gaacatcttg atcatatccg cgaccagctg
    25261 gagcgagccg ccccagccaa cgcggtttgg tccataacgg ttctggaaca gacccagcag
    25321 acgacgttcg ccaaagctca tgaaggcccc gcaggtgacg accaccagca gaatcaccac
    25381 cgctttgaga atgctcagca ggatctcaat cagatccggt gtaatccaac tcattgttgc
    25441 gcctcccgca gatcctcaag acgcgcgcca gccagaaccg gcgcgatgcc aggcataccc
    25501 atcggcagcc ctacctgccc tgccgctaac ccttcagaga tttcaaccgg cagcgtcacc
    25561 gtattgccat cgtagctaaa ggagacgcga gtcccggcat tgacgcccaa cttcgcagca
    25621 tccgccgggt taagtttgat atacggctgc ggcatacggc tctggaagac cggagaacgc
    25681 tgagacaatt cgtcgctgcc aaacaggtgg taatacggcg caatacgcca ctgaccgtcc
    25741 tgcgcctgga agcttgccgg cacggtagtg aaataatcca gaccgccctc agtcgcttca
    25801 atcaaacgca cgcccggatc gccgtgacgc agtttgccgc ccacttcatc ctggaatttg
    25861 ttccacgcct gcggagagtt ccagcccggc gcccaggcga acggaatttc agatcgcggg
    25921 gcagtcggtt ggttattccc ttccattgag aaggcgaaca tggtgtcttt atcctgcggc
    25981 tgacgtggtt catgcacgct gatattggcg cgcatcgccg tacgaccgct gtaacgatgc
    26041 ggttcgcgcg ccagcttctg cccacgaatg cggaaggtcg catccggcgc ggcgtcctta
    26101 atgccggcaa attgcggcat ggcggcaatg accgcgtcga tcacatggtc aagctgtgtc
    26161 cagtccactt cgcggttttc gacggtgctg tgcagcgaat gcagccagcg ccagctttcc
    26221 agcataatcg tcttgttatc gtagtaggcc gggtcataaa cctggaagaa gcgctgcgcg
    26281 cggccttcgt tgttgatgac cgtaccatcg ctttcggcga agcttgccgc ggaaagcacc
    26341 agatgagcat tttccataat cgccgtgcgc tgatggtcaa ccaccatcac cagcggcgct
    26401 ttggcgagcg cggcgttcac gcgcgtagcg cttgcatgac ggtggagatc gttttccagc
    26461 accaccaccg cgtccgcgct gccggtttcc agctcgccca acgcatcgtc aagcgaaccg
    26521 ccgcccatca tacccagccc catgctgttc acggagcggg caatcatagt aataccgacg
    26581 tcggcgccac ggcctttcag cgctttcgcc acgttggcgg ccgcctgaat cacctcactg
    26641 ctaccggcgt tagtgccgga gataatcagc ggttttttcg cgccggccaa cgcctgcaca
    26701 atgacatcaa ttttgttttg caagtcgctg tcgataccgt caaccgcagg cgctgtattg
    26761 tccagcgcat gggcaatcgc aaagcccagg cgcgcctgat cttccaccgg cgcgcgataa
    26821 gtccaggcgg cgatatcatc cagacgggtg tcgtccacgt tagtcacgaa cagcggatgt
    26881 ttggcacgct ggccgatgtt aaggatggcc gcaatctgcc agtcggccac tttctgcgcc
    26941 gccgccattt cacgcgcttt acctttcacc gcctggcgta ccgccagcgc aacgcgcgcg
    27001 ccggtctgag tgacatcctc acccaagacc agtaccgcgt cataagattc gatctcccgc
    27061 agcgccgggg tgtaaattcc gccttcacgc agcactttca gcgccagttg cagacgttcc
    27121 tgctcgccgc gcgcgatacc ggtgtagaag ttttccgcac caaccagctc acgcagcgca
    27181 aagttgctct caatgctggc gcgtggcgaa ccgataccga tcactttctt cgactggcgc
    27241 agaatatccg ccgcgccctg catcgcctgc tcggcgttga gagtaataaa gtcatcgcca
    27301 cgacgctgaa ccggctgacg cgggcggtct ttcaggttca catagccata gccgaaacga
    27361 ccgcggtcgc agaggaagta atggttaacg gtaccgttgt aacggttttc gatacggcgc
    27421 agttcgccat agcgctcgcc cgggctgatg ttacagccga tggaacactg ctggcagatg
    27481 ctcggcgcaa actgcatgtc ccatttacgg ttgtaacgct cggagtgcgt tttatcggtg
    27541 aagacgccgg tcgggcaaat ctcgaccagg ttaccggaga attcgctttc cagcgtaccg
    27601 tcttccggac gcccgaagta gacgttgtca tgcgcgccat agacgcccag atcggtaccg
    27661 tcagcataat ctttgtagta acgtacacaa cggtagcagg cgatgcagcg gttcatttcg
    27721 tgcgagatga acggccccag atcctggttg cggtgggtac gtttggtgaa acggtagcgg
    27781 cggaaactgt gacccgtcat cacggtcata tcctgaagat ggcagttacc gccctcttca
    27841 cagaccggac agtcgtgcgg gtggttagtc atcagccact ccaccacgct ttcacggaac
    27901 tgtttcgctt cttcgtcgtc aatagagata aaggtaccgt cggtggctgg cgtcatacag
    27961 gacatcacca ggcgaccacg cgtatcttcc gcgttttggt attgcttcac cgcacactgg
    28021 cggcaagcac cgacgcttcc cagcgccggg tgccagcaaa aatacggaat atcaaggccg
    28081 agggacagac atgcctgtag caggttgtcc gcgccgttga cctcgtattc tttgccgtct
    28141 acatgaatcg tagccattag catgcttcca aattaaaaat cgttaactca ccagcgctct
    28201 ttgagcaggt tcggctgaat accattgatt aaatgggtat tactgaacgg ctgcttgatg
    28261 ccagcttcga attcttcgcg gaaatactta attgcgcttt gcagtggctc aaccgcgccc
    28321 ggcgcatgcg cgcagaaggt tttacccggc ccgaggaatc gacacagttg ctcaagcgtc
    28381 tcgatatccc ccggctggcc ttcgccacgc tccagcgcgc gcagaatttt cacgctccac
    28441 ggcaacccgt cgcggcatgg cgtacaccag ccgcaggatt cgcgggcaaa gaactcttcc
    28501 aggttacgca ccagcgacac catgccgatt tcgtggtcta ccgccatcgc cagcgcggtg
    28561 cccagacggc tccccgcttt accgatgctt tcgaattcca tcggcagatc gaggtgtgct
    28621 tcggtcagga agtctgtccc cgcgccgccc ggttgccagg ctttgaattt caggccgtca
    28681 cgcataccgc cggcgtagtc ttcgaggatc tcgcgcgcga tggtgccgaa cggtaattcc
    28741 cacaggcccg gattcttcac gcggcccgag aagcccatca gcttggtacc cgcatctttg
    28801 cttttcgaga tgttctggta ccactccacg ccgttggcga ggattgccgg gacgttacac
    28861 aacgtttcga cgttattcac acaggtcggc ttgccccata cgccggaggt cgccgggaaa
    28921 ggcggcttgg agcgcgggtt cgcgcggcgg ccttcgaggg agttaatcag cgccgtttct
    28981 tcaccacaga tgtaacgccc tgccccggtg tggacaaaca gttcgaagtc gaacccggtg
    29041 cccatgatat ttttgccaag cagcccggcc tcggttgctt cggcaatcgc acggcgcaga
    29101 tgtacagccg cttcgatata ttcgccgcgc aggaagatgt aaccacgata cgctttcagc
    29161 gcgaacgcgg agatcagcat gccttccacc agcaggtgcg gcagttgttc catcagcaga
    29221 cggtctttat aggtgcccgg ctccatttca tcggcgttac acagcaggta acggatgttc
    29281 atggattcat ctttcggcat caggctccac ttcagaccgg tggaaaagcc cgcgccgccg
    29341 cgccctttca gaccagcgtc ttttacctgg ctgacgattt catccggaga caggccggtc
    29401 agcgccttac gcgcgccttc gtagccgttt ttgctacgat attcatccag ccagaccggc
    29461 tgtttgtcat cgcgcagacg ccaggtcagc ggatgggttt cgggagtacg gataacgttt
    29521 ttcatttata ccgctccagt agttcaggaa tggcttccgg ggtcagatgg ctgtgagtat
    29581 cctcatcaat catcatgttc ggccctttat cgcaattccc caggcagcag gtcggcagca
    29641 gcgtaaagcg gccatcaaag gtcgtctgcc ccggtttgat gttgagattt ttttccagcg
    29701 cggcctgaat cccctgatag ccggtgatat ggcacaccac gctgtcgcag tagcgaatca
    29761 cgtggcgacc gaccggctga cggaagatct ggctgtagaa tgtggcgacg ccttcgacgt
    29821 cgctcgccgg aatacccagc acatcggcaa tagcgtagat cgcgccgtcc ggcacccagc
    29881 cacgctgctt ctgaacgatt ttcagcgctt caatggacgc cgcacgcggg tcttcgtagt
    29941 ggtgcttctc gtgctctatc gcttcacgct ctgccgcact cagctcaaaa gcctcggttt
    30001 gtggttgttg attctcgtgc ataattagcg gtccacatct gacataacaa aatcgatact
    30061 acccagatag acaatcaggt cggagaccag gctaccgcgg atcgccgagg gaatctgctg
    30121 caggtgcgca aagctcggcg tgcgcacgcg ggtacggtag ctcatagtgc tgccgtcgct
    30181 ggtcaggtag taactgttaa tccccttcgt cgcttccacc atctggaagg actcctgcgc
    30241 cggcatcacc gggccccagg agacctgcag gaagtgggtg atcagggttt cgatatgttg
    30301 cagcgtgcgc tctttcggcg gcggcgtggt cagcgggtga tccgctttga acggcccttc
    30361 cggcatgtta tcgaggcact gctgaagaat gcgcagactc tggcgcagct cttccacttt
    30421 cagcatcacg cgggtatagc agtcggaaac gccgccgccc accggcactt caaagtcaaa
    30481 gttttcgtag ccagaatatg gacgccattt acgcacgtcg aagtctatcc cggtcgcgcg
    30541 cagccctgcg ccggtggtgc cccactccag cgcctctttc gcgccgtaag cggcaacgcc
    30601 ctgcgaacgc cctttcagaa tggtgttacg cagcgcggct ttctcgtaag agtccagacg
    30661 cttcggcatc cactcaagga actctcgcag caggcgatcc caaccgcgcg gcaagtcgtg
    30721 cgcgacgccg ccgatacgga accaggccgg gtgcatacgg aaaccggtaa tggcttccac
    30781 cagatcataa attttctgcc ggtcggtaaa ggcaaagaag accggggtca tcgcgccgac
    30841 gtcctgaata aaggtcgaaa tgtacagcag atgactgtta atgcggaaca gttcggagag
    30901 catcacgcgg atgacgttca cacgatccgg gacggtgatc cccgccagtt tttctaccgc
    30961 cagcacgtac ggcatttcat tgacgcaacc accgaggtat tcgatacggt cggtataggg
    31021 aatgtagcta tgccaggact ggcgctcgcc cattttttcg gcgccgcggt ggtgatagcc
    31081 gatatccggc acgcagtcga cgatttcttc gccgtcaagt tgcaggataa tacgaaacgc
    31141 accgtgcgca gacgggtggt tcgggccgag gttgaggaac ataaagtcct cgttgtcagt
    31201 cccgcgcttc atcccccagt cttccggctt aaaggtcaac gcttccatct ccagatcctg
    31261 cttggctttg gtcagctcaa acgggtcgaa ttcggtcgcg cgcgccggat aatctttacg
    31321 cagcggatgg ccttcccagg tttgcggcat catgatgcgc gtcaggtgcg ggtggccttc
    31381 gatatcaatg ccaaacatct cccaggtctc acgctcgtac cagttggcgt tagggaaaag
    31441 tttagtgaag gtcggcacgc gcaggtcgtt ttcagacaac gccaccttga gcataatatc
    31501 gcgattacgc tcaatggaaa tcaggtggta gaaaacggaa aaatccgcgg cgggtaaccc
    31561 gtcacggtgc gtacgcaggc gttcatccat gccgtgtaag tcaaacagca tgacgtaagg
    31621 tttcggcagt ttctttaaga aatcgccaac ctccagtagt tgttcacgct tgacccaaac
    31681 aacggggata ccggtgcggg tcgcctgaac ggtaaaggca tccggcccaa aacggttgcg
    31741 cagttcgccg ataaccggat catcaagatg atcgcgggta ctccatgcag cgtcttgcgc
    31801 ggttaagtcg gtcatattgt tcaccattgc aaatggtccg tggtggtcgg cagtgcttcg
    31861 cgctattaaa atagtggtta gcgaagtgaa gtgctgctgc cgacaggcgc aaattaaatc
    31921 tcgtccgggg tacgcaggtt cgtgacggca atacgctcgc cgcgtttacg ttcgcgttct
    31981 ggctgcatat tggcgcgata cacgccctga tcgcccacca cccatgagag cggacggcgc
    32041 tctttgccaa tcgattcttg cagcagcatc aacgcttgca tatacgcttc cggacgcggc
    32101 ggacagccag ggatatacac atccaccggg ataaacttat caacgccctg cactaccgaa
    32161 taaatatcgt acatgccgcc ggagttggcg caggcgccca tagaaatgac ccattttggc
    32221 tccagcattt ggtcatacag acgctgaata accggagcca ttttggtaaa gcaggtaccg
    32281 gccaccacca tcagatcagc ctgacgtggc gacgcacgca gcacttccgc gccgaaacgg
    32341 gcaacgtcat gcactgcggt aaacgaggtc accatctcta catagcagca agaaaggccg
    32401 aagttgtagg gccaaattga gtttttacgg ccccagttaa ccatgtcatg cagtttgccc
    32461 atgaacacgt ttttgttaac ttcctgctcc agggggtcgg ttacgatctc ctgtttttgc
    32521 agggggtaac ggtcattctc accgttagga tctatgcggg tgagcgtata atccatctta
    32581 atgcctcgcg gttagcgttg acgattagcg atactgttcg tttccgggtt catacgctcg
    32641 cggcgtgaac gcgcgggcgt ccagtccaac gcgccaatac gcgccagata aaccagacca
    32701 gccagtaaca caaaaataaa aattgcagct tccacaaagc caacccagcc gctttcgcgg
    32761 atagaagttg accatgcgaa cagatacagc gcttcaacgt cgaagataac gaagaacatg
    32821 gctaccaggt aaaacttggc agacaagcgt aagcgggcgg tgccgaccga gtcgatacct
    32881 gattcaaacg gaacgttctt gtgcctcgcg cgtgcgcgac cgcccaaaaa ccaaccgcct
    32941 accagcatca ggcagcacag gccaatggca acgataagaa agatagcgaa tgcccagtga
    33001 tgagcgatga cttcagtgga tgttgacata ctcattgctt actcatcaaa agtagcgcca
    33061 gttcctctgc tctttacggc agatggacgc cacatcgatt caggggagga ataaaaaaac
    33121 cctacaatta ctgtagaaaa tgataaaaac agctaattga tgtggttttt tactcctttc
    33181 tataaccttt tgtcaacttt aacaaaagtt ccttcacatt aatttacatc aattcatcat
    33241 c
//
LOCUS       DAJVBX010000020        33221 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.020, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000020 DAJVBX010000000
VERSION     DAJVBX010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 33221)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33221)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33221
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.020"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            103..1892
                     /locus_tag="OPV72_000882"
                     /pseudo
     CDS             103..1892
                     /locus_tag="OPV72_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462979.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aryl-sulfate sulfotransferase"
     gene            2093..2755
                     /locus_tag="OPV72_000883"
     CDS             2093..2755
                     /locus_tag="OPV72_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02117 family protein"
                     /protein_id="HCR9913254.1"
                     /translation="MKNLFIAWLSLLLYGCTTFPQAVKPTTGGQPSPTEIYIVSHGWH
                     TGIIAPAHDVNTVLPQLKKRFAQETQWYEIGWGDKGFYQSQEITTALTLQAMFWSSGA
                     VMHIVAFSGQPERYFAGSEIKSLLLHTNQRNSLMRYLGRSFARDAEGNLIPLKQGIYG
                     DSQFYAANGRYGILNTCNKWTAKGLESAGLTINPSLKLTAGSVMKAITDHRMCLNKYC
                     YP"
     gene            complement(2801..3013)
                     /gene="rpmE"
                     /locus_tag="OPV72_000884"
     CDS             complement(2801..3013)
                     /gene="rpmE"
                     /locus_tag="OPV72_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="HCR9913255.1"
                     /translation="MKKGIHPNYVEITATCSCGNVIKTHSTVGHDLNLDVCGKCHPFF
                     TGKQRVVDTGGRVERFNKRFSIPGSK"
     gene            3217..5415
                     /gene="priA"
                     /locus_tag="OPV72_000885"
     CDS             3217..5415
                     /gene="priA"
                     /locus_tag="OPV72_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HCR9913256.1"
                     /translation="MSVAHVALPVPLPRTFDYLLPEGGVAKAGCRVRVPFGKQQERVG
                     IVVSVSDHSELPLDELKSVIEILDNEPIFSPSIWRLLLWAADYYHHPLGDVLFHALPV
                     LLRQGKPASNAPLWYWFATEEGQAVDINSLKRSAKQQQALAALRQGKIWRYQVAELDF
                     TDATLQTLRRKGLCELASETPAFTDWREHYAVAGERLRLNTEQATAVGAIHSASDGFS
                     AWLLAGVTGSGKTEVYLSVLENVLAQGKQALVMVPEIGLTPQTIARFRERFNTPVEVL
                     HSGLNDSERLSAWLKAKNGEAAIVIGTRSSLFTPFKNLGVIVIDEEHDSSYKQQEGWR
                     YHARDLAVYRAHSEQIPIILGSATPALETLCNVRQKKYRMLRLTRRAGNARPALQHVL
                     DLKGQRLQAGLAPALIARMRQHLQADNQVILFLNRRGFAPALLCHDCGWIAECPRCDH
                     YYTLHQAQHHLRCHHCDSQRPVPRQCPSCGSTHMLPVGLGTEQLEQVLAPFFPGVPIS
                     RIDRDTTSRKGALEQHLAEVHRGGARILIGTQMLAKGHHFPDVTLVALLDVDGALFSA
                     DFRSAERFAQLYTQVSGRAGRAGKQGEVVLQTHHPEHPLLQTLLYKGYDAFAEQALAE
                     RQTLQLPPWTSHVIIRAEDHNNQQAPVFLQQLRNVIQASPLSDDKLWILGPVPALAPK
                     RGGRYRWQILLQHPSRILLQHIISGTLALINTLPEARKVKWVLDVDPIEG"
     gene            5570..6595
                     /gene="cytR"
                     /locus_tag="OPV72_000886"
     CDS             5570..6595
                     /gene="cytR"
                     /locus_tag="OPV72_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator CytR"
                     /protein_id="HCR9913257.1"
                     /translation="MKSNKQVTAATMKDVALKAKVSTATVSRALMNPDKVSQSTRSRV
                     EQAALEVGYFPQSMGRNVKRNESRTILVIVPDICDPFFSEIIRGIEVTAAEQGYLVLI
                     GDCAHQNQKEKTFLNLIITKQIDGMVLLSSRLPFDASVEEQRNLPPMVMSNEFAPELE
                     LPTVHIDNLTAAFNAMNYLLDLGHKRIGCIAGPEDMPLCHYRLQGYVQALRRSGIVVD
                     PHYIARGDFTFEAGANALKQLLEQPLPPTAVFCHSDVMALGALSWAKRQGLKVPDDLS
                     IIGFDNIALAEFCDPPLTTVAQPRFDIGREAMLLLLDQMQGQNVSSGSRLMDCELIIR
                     GSTRALP"
     gene            6689..7693
                     /gene="ftsN"
                     /locus_tag="OPV72_000887"
     CDS             6689..7693
                     /gene="ftsN"
                     /locus_tag="OPV72_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsN"
                     /protein_id="HCR9913258.1"
                     /translation="MAQRDYVRRGQPAPSRRKKSTSRNSRKKQSNMPAVSPAMVAIAA
                     AVLVTFIGGLYFITHHKKEESETLQNQKVTGNGLPPKPEERWRYIKELESRQPGVRTP
                     TEPSAGGEVMNPNQLTSEQRQLLEQMQADMRQQPTQLNEVPWNEQTPEQRQQTLQRQR
                     QAQQQQQQQQQQQQQQWAQTQPVQQPRTQPRVNEQPQTRTVQSAPAQPARQSQPPKQT
                     ASQQPYQDLLQTPAHTSAAAPKAAPITRAPEAPKATAEKKDERRWMVQCGSFKGAEQA
                     ESVRAQLAFEGFDSKITTNNGWNRVVIGPVKGKENADSTINRLKMAGHTNCIRLATGG
                     "
     gene            7785..8315
                     /gene="hslV"
                     /locus_tag="OPV72_000888"
     CDS             7785..8315
                     /gene="hslV"
                     /locus_tag="OPV72_000888"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease subunit HslV"
                     /protein_id="HCR9913259.1"
                     /translation="MTTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVI
                     AGFAGGTADAFTLFELFERKLEMHQGHLVKAAVELAKDWRTDRMLRKLEALLAVADET
                     ASLIITGNGDVVQPENDLIAIGSGGPYAQAAARALLENTELGAREIAEKALDIAGDIC
                     IYTNHFHTIEELTAKA"
     gene            8325..9656
                     /gene="hslU"
                     /locus_tag="OPV72_000889"
     CDS             8325..9656
                     /gene="hslU"
                     /locus_tag="OPV72_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019841241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase ATPase subunit"
                     /protein_id="HCR9913260.1"
                     /translation="MSEMTPREIVSELNKHIIGQDNAKRSVAIALRNRWRRMQLDEEL
                     RHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRD
                     LTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAKNNWGQAEQQQEPSAARQTFR
                     KKLREGQLDDKEIEINLAAAPMGVEIMAPPGMEEMTSQLQSIFQNLGGQKQKPRKLKI
                     KDAMKLLVEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKRGETSGPDVSREG
                     VQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQVAKPSDLIPELQGRLPIRVELQA
                     LTTSDFERILTEPNASVTVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNETTENIGA
                     RRLHTVLERLMEEISYNASDLHGQNITIDAEYVSKHLDALVADEDLSRFIL"
     gene            9723..10652
                     /gene="menA"
                     /locus_tag="OPV72_000890"
     CDS             9723..10652
                     /gene="menA"
                     /locus_tag="OPV72_000890"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HCR9913261.1"
                     /translation="MTEQQQISRTQAWLESLRPKTLPLAFAAIIVGTALAWWQGYFDP
                     LVALLALITAGLLQILSNLANDYGDAVKGSDKPDRIGPLRGMQKGVITQQEMKRALII
                     TVVLICISGLALVAVACHTLTDFVGFLILGGLSIIAAITYTVGNRPYGYIGLGDISVL
                     VFFGWLSVMGSWYLQAHTLIPALILPATACGLLATAVLNINNLRDINSDRENGKNTLV
                     VRLGDVNARRYHACLLLGALLCLALFNLLSLHSPWGWLFILAAPLLIKQARYVMRERE
                     PAAMRPMLERTVKGALLTNLLFVIGILLSQWAV"
     gene            10745..11230
                     /gene="rraA"
                     /locus_tag="OPV72_000891"
     CDS             10745..11230
                     /gene="rraA"
                     /locus_tag="OPV72_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001392924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease E activity regulator RraA"
                     /protein_id="HCR9913262.1"
                     /translation="MKYDTSELCDIYQEDVNVVEPLFSNFGGRSSFGGQIITVKCFED
                     NGLLYDLLEQNGRGRVLLVDGGGSVRRALVDAELARLATQNEWEGLVIYGAVRQVDDL
                     EELDIGIQAIAAIPVGAAGEGIGESDVRVNFGGVTFFSGDHLYADNTGIILSEDPLDI
                     E"
     gene            complement(11452..11691)
                     /gene="zapB"
                     /locus_tag="OPV72_000892"
     CDS             complement(11452..11691)
                     /gene="zapB"
                     /locus_tag="OPV72_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septal ring assembly protein ZapB"
                     /protein_id="HCR9913263.1"
                     /translation="MSLEVFEKLEAKVQQAIDTITLLQMEIEELKEKNNSLTQEVQSA
                     QHQREELERENNFLKEQQSGWQERLQALLGRMEEV"
     gene            12090..12935
                     /locus_tag="OPV72_000893"
     CDS             12090..12935
                     /locus_tag="OPV72_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HCR9913264.1"
                     /translation="MSQTSTLKGQCIAEFLGTGLLIFFGVGCVAALKVAGATFGQWEI
                     SVIWGLGVAMAIYLTAGVSGAHLNPAVTIALWLFACFDKRKVVPFIISQVAGAFCAAA
                     LVYGLYYNLFVDFEQTHHIVRGSVESLELAGIFSTYPNPHINFVQAFAVEMVITAILM
                     GLILALTDDGNGVPRGPLAPLLIGLLIAVIGASMGPLTGFAMNPARDFGPKMFAGLAG
                     WGEIAFTGGRDIPYFLVPLFGPIVGAILGAFAYRKFIGRHLPCDICVVEEKDSTAATQ
                     QNASL"
     gene            12956..14461
                     /gene="glpK"
                     /locus_tag="OPV72_000894"
     CDS             12956..14461
                     /gene="glpK"
                     /locus_tag="OPV72_000894"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HCR9913265.1"
                     /translation="MTEKYIVALDQGTTSSRAVVMDHDANIVSVSQREFEQIYPKPGW
                     VEHDPMEIWASQSSTLVEVLAKADISSDQIAAIGITNQRETAIVWERETGKPIYNAIV
                     WQCRRTANICEQLKRDGLEDYIRDNTGLVVDPYFSGTKVKWILDHVEGSRERAKRGEL
                     LFGTVDTWLIWKMTQGRVHVTDYTNASRTMLFNIHDLDWDDKMLDVLDIPRAMLPQVR
                     KSSEVYGQTNIGGKGGTRIPIAGIAGDQQAALFGQLCVKEGMAKNTYGTGCFMLMNTG
                     EKAVKSENGLLTTIACGPSGEVNYALEGAVFMAGASIQWLRDEMKLISDAFDSEYFAT
                     KVKDTNGVYVVPAFTGLGAPYWDPYARGAIFGLTRGVNSNHIIRATLESIAYQTRDVL
                     EAMQADSGIRLHALRVDGGAVANNFLMQFQSDILGTRVERPEVREVTALGAAYLAGLA
                     VGYWQNLDELQEKAVIEREFRPGIETTERNYRYSGWKKAVKRAMAWEEHDK"
     gene            14573..15583
                     /gene="glpX"
                     /locus_tag="OPV72_000895"
     CDS             14573..15583
                     /gene="glpX"
                     /locus_tag="OPV72_000895"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphatase"
                     /protein_id="HCR9913266.1"
                     /translation="MRRELAIEFSRVTEAAALAGYKWLGRGDKNTADGAAVNAMRIML
                     NQVNIDGTIVIGEGEIDEAPMLYIGEKVGTGHGDAVDIAVDPIEGTRMTAMGQANALA
                     VLAVGDKGCFLNAPDMYMEKLIVGPGAKGAIDLNLPLADNLRNIADALGKPLGDLTVT
                     ILAKPRHDEVIAEMAKLGVRVFAIPDGDVAASILTCMPDSEVDVLYGIGGAPEGVVSA
                     AVIRALDGDMQGRLLARHDVKGDSEENRRIGEQELARCKAMGIEAGKALCLGDMARSD
                     NVIFSATGITKGDLLEGISRKGHIATTETLLIRGKSRTIRRIQSIHYLDRKDPDVQAH
                     IL"
     gene            15680..16426
                     /gene="fpr"
                     /locus_tag="OPV72_000896"
     CDS             15680..16426
                     /gene="fpr"
                     /locus_tag="OPV72_000896"
                     /EC_number="1.18.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin--NADP(+) reductase"
                     /protein_id="HCR9913267.1"
                     /translation="MADWVTGKVTKVQNWTDALFSLTVHAPINPFTAGQFTKLGLEID
                     GERVQRAYSYVNAPDNPNLEFYLVTVPQGKLSPRLAALKPGDEVQVVSDASGFFVLDE
                     VPDCETLWMLATGTAIGPYLSILQYGQDVTRFKNLVLVHAARFAADLSYLPLMLELQQ
                     RYEGKLRIQTVVSRESVPGSLTGRVPALIENGELEKAVGLPMDKETSHVMLCGNPQMV
                     RDTQQLLKETRQMTKHLRRRPGHMTAEHYW"
     gene            complement(16533..16961)
                     /locus_tag="OPV72_000897"
     CDS             complement(16533..16961)
                     /locus_tag="OPV72_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF805 domain-containing protein"
                     /protein_id="HCR9913268.1"
                     /translation="MTIQQWLFSFKGRIGRRDFWIWIGLWFAGMLALFSLAGKNLLDI
                     QTAAFCLVCLLWPTAAVMVKRLHDRGRSGAWALLMILAWMLLAGNWVMLPGMWQWVVG
                     RFIPTLILVMMLIDLGAFVGVQGENKFGKATQDVKFKAEP"
     gene            17062..17658
                     /locus_tag="OPV72_000898"
     CDS             17062..17658
                     /locus_tag="OPV72_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiiQ family protein"
                     /protein_id="HCR9913269.1"
                     /translation="MKPGCTLFLLLFSALTASITAHAQLSSSTTTAPYLLAGSPTFDL
                     SISQFRENFNRQNPDLPLNEFRAIENSRDKANLTRAASKINENLYASTALERGTLKVK
                     SMQITWLPIQGPEQKAAKAKALEYMAAIIRTVAPLLTKEQSQKKLQKMLIAGKGKHYY
                     AETEGAVRYVVADNGEKGLTFAVEPIKLALSENLEGAN"
     gene            17771..18538
                     /gene="tpiA"
                     /locus_tag="OPV72_000899"
     CDS             17771..18538
                     /gene="tpiA"
                     /locus_tag="OPV72_000899"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HCR9913270.1"
                     /translation="MRHPLVMGNWKLNGSRHMVNELVANLRKELTGVAGCDVAIAPPE
                     MYIDLAKRAAAGSHIMLGAQNVDLNLSGAFTGETSAEMLKDIGAQYIIIGHSERRTYH
                     KESDELIAKKFAVLKEQGLTPVLCIGETEAENEAGKTEEVCARQIDTVLKTQGAAAFE
                     GAVIAYEPVWAIGTGKSATPAQAQAVHKFIRDHIAKADAKIAEQVIIQYGGSVNASNA
                     AELFAQPDIDGALVGGASLKADAFAVIVKAAEAAKQA"
     gene            complement(18630..19394)
                     /locus_tag="OPV72_000900"
     CDS             complement(18630..19394)
                     /locus_tag="OPV72_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HCR9913271.1"
                     /translation="MNSQFAGLTREACVALLASYPLSVGILAGQWIALHRYLQQLEAL
                     NQPLLHLDLMDGQFCPQFTVGPWAVGQLPQTFIKDVHLMVADQWAAAQACVKAGAHCI
                     TLQAEGDIHLHHTLSWLGQQTVPVIDGEMPVIRGISLCPATPLDVIIPILSDVEVIQL
                     LAVNPGYGSKMRSSDLYERVAQLLCLLGDKREGKIIVIDGSLTQDQLPSLIAQGIDRV
                     VSGSALFRDDRLVENTRSWRAMFKVAGDTTFLPSTA"
     gene            complement(19404..19694)
                     /gene="lsrG"
                     /locus_tag="OPV72_000901"
     CDS             complement(19404..19694)
                     /gene="lsrG"
                     /locus_tag="OPV72_000901"
                     /EC_number="5.3.1.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione
                     isomerase"
                     /protein_id="HCR9913272.1"
                     /translation="MHVTLVEINVHDDKVEQFIDVFRQNHLGSIKEPGNLRFDVLQDP
                     QVPTRFYIYEAYVDEQAVAFHKTTPHYKTCVEQLEPLMTGPRTKKVFMGLMP"
     gene            complement(19777..20652)
                     /gene="lsrF"
                     /locus_tag="OPV72_000902"
     CDS             complement(19777..20652)
                     /gene="lsrF"
                     /locus_tag="OPV72_000902"
                     /EC_number="2.3.1.245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxy-5-phosphonooxypentane-2,4-dione
                     thiolase"
                     /protein_id="HCR9913273.1"
                     /translation="MADLDDIKDGKDFHTDKPQTNTLFSLKGCGALDWGMQSRLARIF
                     NPRTRKTVMLAFDHGYFQGPTTGLERIDINIAPLFEYADVLMCTRGILRSVVPPAINK
                     PVVLRASGANSILTELSNEAVAVAMDDAVRLNSCAAAAQVYIGSEHEHQSIKNIIQLI
                     DAGLRVGMPIMAVTGVGKDMARDQRYFSLATRIAAEMGAQIIKTYYVDKGFERIAAGC
                     PVPIVIAGGKKLPEREALEMCYQAIDQGASGVDMGRNIFQSEDPVAMIKAVHAVVHHN
                     ETAERAYELFLSEKG"
     gene            complement(20681..21703)
                     /gene="lsrB"
                     /locus_tag="OPV72_000903"
     CDS             complement(20681..21703)
                     /gene="lsrB"
                     /locus_tag="OPV72_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer 2 ABC transporter substrate-binding
                     protein LsrB"
                     /protein_id="HCR9913274.1"
                     /translation="MARHSIKMIALLTAFGLASAVMTVQAAERIAFIPKLVGVGFFTS
                     GGNGAQEAGKALGIDVTYDGPTEPSVSGQVQLVNNFVNQGYDAIIVSAVSPDGLCPAL
                     KRAMQRGVKILTWDSDTKPECRSYYINQGTPKQLGSMLVEMAAHQVDKEKAKVAFFYS
                     SPTVTDQNQWVKEAKAKISQEHPGWEIVTTQFGYNDATKSLQTAEGIIKAYPDLDAII
                     APDANALPAAAQAAENLKRNNLAIVGFSTPNVMRPYVQRGTVKEFGLWDVVQQGKISV
                     YVANALLKNMPMNVGDSLDIPGIGKVTVSPNSEQGYHYEAKGNGIVLLPERVIFNKDN
                     IDKYDF"
     gene            complement(21732..22707)
                     /gene="lsrD"
                     /locus_tag="OPV72_000904"
                     /pseudo
     CDS             complement(21732..22707)
                     /gene="lsrD"
                     /locus_tag="OPV72_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462957.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer 2 ABC transporter permease LsrD"
     gene            complement(22704..23747)
                     /gene="lsrC"
                     /locus_tag="OPV72_000905"
     CDS             complement(22704..23747)
                     /gene="lsrC"
                     /locus_tag="OPV72_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer 2 ABC transporter permease LsrC"
                     /protein_id="HCR9913275.1"
                     /translation="MLKFIQNNREATALLAIVCLFVFLGALDSQYLSVQTLTMVFSSA
                     QILMLLAIGATMVMLTRNIDVSVGSTTGMCAVLLGVMLNAGYSLPVACLATLILGIVA
                     GFFNGVLVAWLKIPAIVATLGTLGLYRGIMLLWTGGKWIEGLPAGLKQLSAPVFLGIS
                     AIGWFTLVLALLMAWLLAKTAFGRNFYATGDNLQGARQLGVRTEMVRIMAFSLNGGMA
                     ALAGIVFASQIGFIPNQTGTGLEMKAIAACVLGGISLLGGSGTVIGAILGAYFLTQID
                     SVLVLLRIPAWWNDFIAGLVLLGVLVFDGRLRCALQRNLRRQKYARFISPPTPLQAEA
                     KTHAQQNKNKEVA"
     gene            complement(23741..25276)
                     /gene="lsrA"
                     /locus_tag="OPV72_000906"
     CDS             complement(23741..25276)
                     /gene="lsrA"
                     /locus_tag="OPV72_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer 2 ABC transporter ATP-binding
                     protein LsrA"
                     /protein_id="HCR9913276.1"
                     /translation="MQISHNTASPLICVQNIYKSYSGVEVLKGIDFTLHAGEVHALLG
                     GNGAGKSTLMKIIAGIVPPDGGTIDIAGVRCSHLTPLKAHQYGIYLVPQEPLLFPSLS
                     VRENILFGLQGRQASTEKMQQLLKAMGCQLDPASAAGTLDVADRQIVEIMRGLMRDSR
                     ILILDEPTASLTPAETDRLFTRLQELLKKGVGIVFISHKLPEIRQLAHCVSVMRDGKI
                     ALFRKTHDLSTDEIIQAITPATQGVSLSASQKLWLELPGSRPQNERGATVLALESLTG
                     EGFMNINLEVRAGEILGLAGLVGAGRTELAETLYGIRPVNAGRMLFNGEEINALTTQQ
                     RLQLGLVYLPEDRQSSGLYLDASLAWNVCSLTHNQKGFWIKPQRDNATLERYHRALNI
                     KLNNAEQAARTLSGGNQQKVLIAKCLEASPQLLIVDEPTRGVDVSARSDIYQLLRSIA
                     QQNVAVLFISSDLEEIEQMADRVYVMHQGELGGPALCGEEINVDTIMHVAFGEHGASE
                     ATC"
     gene            25532..26491
                     /gene="lsrR"
                     /locus_tag="OPV72_000907"
     CDS             25532..26491
                     /gene="lsrR"
                     /locus_tag="OPV72_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LsrR"
                     /protein_id="HCR9913277.1"
                     /translation="MSDNTLVSDYGMCEEEQVARIAWFYYHDGLTQSEISERLGLTRL
                     KVSRLLEKGHQSGIIRVQINSRFEGCLEYENALRNHFALQNIRVLPALPDADIGLRLG
                     IGAAHMLMESLRPQQLLAVGFGEATMTTLKRLSGFISAQQIRLVTLSGGVGPYMTGIG
                     QLDAACSVSIMPAPLRASSQEIACTLRNENSVRDVMLTAQAADAAIVGIGAINQKDQA
                     SILKSGYITQGEQLMIGRKGAVGDILGYFFDAHGEIIPDIKIHNELIGLKLNSLSTIP
                     TVIGVAGGEQKAEAIIAAMRGNYINALVTDQKTAGKIIQLIEK"
     gene            26578..28170
                     /gene="lsrK"
                     /locus_tag="OPV72_000908"
     CDS             26578..28170
                     /gene="lsrK"
                     /locus_tag="OPV72_000908"
                     /EC_number="2.7.1.189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer-2 kinase"
                     /protein_id="HCR9913278.1"
                     /translation="MARLCTHTESGHYLMALDAGTGSVRAVIFDLQGKQIAVGQAEWQ
                     HLAVPDVPGSMEFDLAKNWQLACQCIRQALQKAAIPATAIAAVSACSMREGIVIYDSN
                     GEPIWACANVDARAAHEVSELKELHDNTFEEEVYRCSGQTLALSAIPRLLWLAHHRPD
                     IYHRASTVTMISDWMAFMLSGELAVDPSNAGTTGLLDLVTRNWKRSLLQMAGLRSDIL
                     SPVKETGTLLGHISQKAAEQCDLQAGTPVIVGGGDVQLGCLGLGVVRPAQTAVLGGTF
                     WQQVVNLPAPVTDPNMNVRINPHVIPGMVQTESISFFTGLTMRWFRDAFCAEEKLIAE
                     RLGIDAYSLLEDMASRVPPGAHGVMPIFSDVMRFKRWYHAAPSFINLSIDPEKCNKAT
                     LFRALEENAAIVSACNLQQIAAFSGVQADSLVFAGGGSKGKLWSQILADVTGLTVHVP
                     VVKEATALGCAIAAGVGVGIWPSLAETGEKLVRWDREHKPNPENFAVYQQAREKWQAV
                     YQDQRALVDGGLTTSLWKAPGL"
     gene            28184..28465
                     /locus_tag="OPV72_000909"
     CDS             28184..28465
                     /locus_tag="OPV72_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HCR9913279.1"
                     /translation="MQKTNEKNHEYRFSDNGPKYLIRGPGCDMGVVILQPGQSFPNHR
                     HNTACEVFYTLSGEVCLYLEGTPHILQTGDVLQCEPGEAHYLINNGDKP"
     gene            complement(28624..28764)
                     /locus_tag="OPV72_000910"
                     /pseudo
     CDS             complement(28624..28764)
                     /locus_tag="OPV72_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462945.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol diphosphatase"
     gene            complement(28771..28941)
                     /locus_tag="OPV72_000911"
     CDS             complement(28771..28941)
                     /locus_tag="OPV72_000911"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913280.1"
                     /translation="MSLWLSYPLILPSIIVGITILLWATSLLPEFMTALLFFAAVVAM
                     GPGKVPARAGMQ"
     gene            complement(29039..29761)
                     /locus_tag="OPV72_000912"
     CDS             complement(29039..29761)
                     /locus_tag="OPV72_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCR9913281.1"
                     /translation="MQVDKTSFTPLYKQLFFIICQQIQNGSLPLGSQLPTQKEIARSY
                     NVSLIVVKQAWSELINAGIISSQRGSGSVVCSVPEGVSYGHTFRGITRDLQDASVAIE
                     NRILEIAPRRARDAQADGLSLPAQHHYLYISRIRCLNNRPFNHEKIYLDLSFFPDLQL
                     TPQALEHTSLYSLLNVTSDSAIEKVEAILPSADLCEKLQIAPNKPLLSVARQTFQAGK
                     DSPFEYCRYYVLSEYFGEIHYH"
     gene            complement(29824..30864)
                     /locus_tag="OPV72_000913"
     CDS             complement(29824..30864)
                     /locus_tag="OPV72_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HCR9913282.1"
                     /translation="MHVDQNKILGCLVGAAAADAMGAATEVRTQQQIKDYFGGWVTTF
                     QKPPADTFGRCNEAGMCTDDFIQAKYIMDALLRHQREVSDEAMREAFQQWLDYPYYAN
                     FTGPTTRAAMKAIFNDNRASLQGELEGEKQSVQIINKGNAEATNGAAMKIWPAAVLHP
                     GDIDAAIDCALQICRFTHNNVLAMSGAAAMAAATSEALRAQTNADSIIAAGIYGAQRG
                     YLLAQEQGAMMVAGPSVARRIELAVDIGKRHRHWETAIVDIADIIGSGLHVSEAVPAA
                     FGLFACCPNSAVDAIISGVNIGNDTDTVATMVGAISGAFHGVEAFPADYLTTLDRMNH
                     FDLAELARQIAG"
     gene            complement(30874..31833)
                     /locus_tag="OPV72_000914"
     CDS             complement(30874..31833)
                     /locus_tag="OPV72_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoimidazole riboside kinase"
                     /protein_id="HCR9913283.1"
                     /translation="MKAMNKVWVIGDASVDLVPEKQNSYLKCPGGASANVGVCVARLG
                     GECGFIGCLGDDDAGRFLRQVFQDNGVDVSSLRLDAALTSAVLIVNLTADGERSFTYL
                     VHPGADTYVSPQDLPPFRQHEWFYFSSIGLTDSPAREACLEGARRMREAGGYVLFDVN
                     LRSKMWRNTDEIPELIARSAALASICKVSADELCQLSGASHWQDARYYLRDLGCDTTI
                     ISLGADGALLITAEGEFHFPAPRVDVVDTTGAGDAFVGGLLFTLSRANCWDHALLAEA
                     ISNANACGAMAVTAKGAMTALPFPDQLNTFLSSHSLAQAMTVK"
     gene            complement(31844..33178)
                     /locus_tag="OPV72_000915"
                     /pseudo
     CDS             complement(31844..33178)
                     /locus_tag="OPV72_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462946.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
BASE COUNT         8340 a         8933 c         8520 g         7428 t
ORIGIN      
        1 ctccgcggat tgttttactt ttttaaatgt tttttcatct ccgataaata agaaggttaa
       61 tatacattca ttttatcgat aatatcgaat ggggaaataa atatgttatt tacaaggaaa
      121 gtcttacctg tattatgctg cctgtgtttg agcggcagcg ttttggcctc aggcgtttta
      181 gacccaaaca ggccaatggt cgcatcagca gatgtcattc cagtacatga agggccatta
      241 ggtatggtcg atgtcgcccc ctacggcggc gttttcccat taacagcaat cattaataaa
      301 gccaatcata atgtacagaa cgtgaaggtt accgttttag ggaaagggga aaaaggtatc
      361 cctatcagtt atgatgtcgg cccgcaggct ataaataccc atgacggcat acctgtattt
      421 ggcttgtatc cagattatgt caataaggtt aaagttgact ggactgaaga aggtaaaaaa
      481 caaacttata cgtggtccat ttacgccgca ccggtatcat taccctctac taccgggcaa
      541 actgccgttc ttcctacggt agaaccggtt aaagtcgata gctcgcttaa aaatcgctta
      601 tatcttttta accatataac ggggatgcca agggcaggcc acattatgca tgtcgcaggc
      661 ggcgcggcga actgggatta taccggtatc aactggatta gcgatacgaa tggcgatgtt
      721 cgcggctata tgaatattga taaattccgt aaccaggatg atataacgcg ctttggttcc
      781 atgatgggct tccatcaggt taacgatggc aatcttattt ttggccaggg tcaacgttac
      841 tttaaatatg atttcttagg ccgcgttatt tccgataaac gactgccaaa aggatttatt
      901 gatttttcgc acgccattac cgaaacgccg aaaggcacct acctgctgcg tgtcgcaaaa
      961 gaaaattatc cattaaatgg taaatacacc atcaatactg tgcgtgatca tattcttgaa
     1021 gttgaccaga acggcgatac cgtcgattac tgggatctgc caaaaatcct cgacccctat
     1081 cgtgacgatg ttattctggc gatggatcag ggagcggtat gtttgagcgt cgatgccgaa
     1141 cattccggtc aggtcatgac caaagagcag cttgcaaaac aacccttcgg cgatatcgcg
     1201 ggctccggcc cgggccgcaa ctgggcgcat gttaactccg tcagctacga tcctcgcgac
     1261 gacagcatta tcattagctc gcgccaccag tctgccatca tcaaaattgg ccgcgataaa
     1321 aaagtgaaat ggatactttc cgatccatcc ggctggaaag gcgaactggc gaaaaaagtg
     1381 ctgaaacccg tagacagcaa cggtaaaccg ctaacctgcg aagcgcacca ctgcgacggt
     1441 ggatttgact ggacatggac acaacatacc ggttggttag tgccatccaa aagcaccgga
     1501 ggtaaaaccg tcgtgaccgc ctttgataac ggcgatgcgc gcggcatgga acaaccggcc
     1561 atgccgtcaa tgaaatattc ccgcggcgtg gaatatcaga ttgacgaaaa aatatgacgg
     1621 tttcccaaat gtgggaatat ggtaaagagc gcggttttga ctggtacagc gccattactt
     1681 ccgtcacgga atatcgcccg gaaaccaaaa cgatgttcat gtactcggcc acagcgggaa
     1741 tgagcggtac aaatccaatc gtttccgttc tggatgaagt caaagacggt actcaggatg
     1801 tgatgctgga gctaaaagta cacagtaacc gtgctggtat gctgggttat cgggcgctga
     1861 ttatcgatcc agagcagatg tttaaaaaat aaagcgtgag agtaaaagta aaacaggcgg
     1921 aagccaactt ccgcctgaat ggttaaaacg tattgtagtt atgacattcg ccttattgcc
     1981 ctcggagagg aatgcaaaaa tatcaatgaa ttaccaatcc ggcaccgacc cgataagcgc
     2041 agcgtcatta gacaaacgcc acaacatacc gcgcctttgc tggtgatatg tcatgaaaaa
     2101 tctctttatc gcctggttaa gtttattgct atatggctgc acaacctttc cacaagccgt
     2161 aaaacctacg acaggcggac agccctcccc gacggaaatc tatatcgtca gtcatggctg
     2221 gcacacggga attattgcgc cggcccatga tgttaatacc gttctgccac agcttaaaaa
     2281 acggttcgct caggagacgc agtggtatga aatcggctgg ggcgataagg gcttttatca
     2341 gtcacaagaa ataaccaccg cgcttacgct ccaggccatg ttctggtcat ccggcgcggt
     2401 tatgcacatc gtcgcctttt ccggtcaacc agaacgctat ttcgccggta gcgagataaa
     2461 atcactgctc ctgcacacaa accagcgtaa cagtctgatg cgttatctgg gccgcagctt
     2521 tgcgcgtgac gcagagggta atctgattcc gttaaaacaa ggaatttacg gcgatagcca
     2581 gttttacgcc gcgaatggcc gctacggcat actcaatacc tgcaataaat ggacagcgaa
     2641 ggggctggaa agcgcgggac tgactataaa tccttcgtta aaactcacgg caggaagcgt
     2701 aatgaaagcg attacggatc acagaatgtg tctgaacaaa tactgttatc cctagaaaac
     2761 aaaaaaagcg ccctgcggcg cttttttttc tggcggtaac ttatttgctg ccagggatgc
     2821 tgaagcgctt gttgaagcgc tcaacacgac caccggtatc aacaacacgc tgcttaccag
     2881 tgaagaacgg gtggcatttg ccgcacacgt ccaggttcag gtcgtgaccc acggtagagt
     2941 gggttttgat aacattaccg caagaacagg ttgcagtaat ttctacgtaa ttcgggtgaa
     3001 tacctttttt catggggaac ctcagtgtaa ggccgcgtcg ctcttccagc cctaacgcca
     3061 gacaccacgc gaagttaata gtaaagggtt tgatgctcac aacacgcacc aaaggcggcg
     3121 aatcatacag aatttgacca ccgtatgcaa actgatccgc gctcccttat cgtaatgtgt
     3181 atactacccg acgaaatttc aagtcaggaa gatgctatgt ccgtcgcgca cgttgccttg
     3241 cccgttccgc ttccccgaac ctttgattac ctgctgccgg aaggcggggt cgccaaagcc
     3301 gggtgccgcg tgcgcgtgcc gttcggcaag cagcaagagc gcgtgggcat tgtcgtctcg
     3361 gttagcgacc acagcgaatt gccgctcgat gaattaaaat cggtcattga aatcctggat
     3421 aacgagccaa tcttttctcc ctccatctgg cgcttactcc tctgggcggc ggattactac
     3481 caccatcccc tcggcgacgt tctgtttcac gctctgccgg ttttactgcg tcagggaaaa
     3541 ccagccagca acgcgcccct atggtattgg ttcgccaccg aagaggggca agccgtcgac
     3601 atcaacagcc tgaaacgctc cgccaaacaa caacaggcgc tggcggcgct gcggcaagga
     3661 aagatctggc gctatcaggt agccgagctt gattttactg acgccacgct gcaaacgctg
     3721 cggcgtaagg ggctttgtga gcttgccagt gaaacgcccg cgtttaccga ctggcgggag
     3781 cattatgccg tcgcaggaga gcgcctgcgg ctaaataccg aacaggcgac agcagtcggc
     3841 gcaattcaca gcgcgtcgga cggtttctcc gcctggttgc tggcaggcgt aaccggttcc
     3901 ggcaagaccg aagtgtatct gagcgtgctg gaaaacgtcc tcgcccaggg caaacaggcg
     3961 ctggtgatgg tgccggaaat cggcctgacg ccgcaaacga tcgcccgttt tcgcgaacgt
     4021 tttaacacgc cggtggaagt gctgcattcc gggctaaacg acagcgagcg tctttcggca
     4081 tggctgaaag cgaaaaacgg cgaagcggcg attgtcatcg gcacgcgctc ctcgctgttt
     4141 acgccgttta aaaatcttgg cgtaattgtc atcgacgaag agcacgacag ctcttataaa
     4201 cagcaggaag ggtggcgcta ccatgcccgc gatttggcag tgtatcgcgc ccatagcgag
     4261 cagatcccga ttattctcgg ctccgccacc ccagccctgg aaacgctatg caacgtgcgg
     4321 cagaaaaaat accggatgct gcgtctgacg cggcgcgcag gcaacgcccg cccagccctg
     4381 cagcatgtgc tggatttaaa aggacagcgt cttcaggcgg gactggcgcc cgcccttatc
     4441 gcccgtatgc gccaacatct ccaggccgat aatcaggtaa ttttatttct taaccgccgg
     4501 ggattcgcgc ccgcgctgct ttgccacgac tgcggctgga ttgcggagtg cccgcgttgc
     4561 gatcactact acacgctgca ccaggcgcag catcatttac gctgccatca ctgcgacagc
     4621 cagcgtccgg taccgcgtca gtgcccctcc tgcggctcca cacatatgct accggttggg
     4681 ttagggaccg aacagctgga gcaggtgctg gcgcccttct tccccggcgt gccgatctca
     4741 cgaatcgacc gtgataccac cagtcgtaaa ggcgcgctgg agcagcatct ggcggaagtt
     4801 caccgcggcg gagcgcgcat tctgataggc acacaaatgc tggcgaaagg ccatcacttc
     4861 ccggacgtca cgctggtggc gttgctggat gtcgatggcg cgcttttttc cgcagatttt
     4921 cgttcggcgg aacgcttcgc ccagctctac actcaggttt ccggccgcgc cgggcgcgcg
     4981 ggtaaacagg gcgaagtggt gctccaaacg caccatcctg agcatcccct gctgcaaacg
     5041 ttactgtata aaggctatga tgcgtttgcg gaacaggcgc tggcggaacg gcaaacgctc
     5101 cagcttccgc cgtggaccag ccacgtcatt attcgcgcag aggatcacaa caatcagcag
     5161 gcgcccgtct ttctccagca gttgcgtaat gtgattcagg ccagcccgct atcagacgat
     5221 aagctgtgga tcttaggtcc ggttccggcc ctcgcgccaa aacgcggcgg ccgctatcgc
     5281 tggcaaattt tacttcagca tccttcacgg attctcctgc aacacatcat cagcggcacg
     5341 ctggcgttga tcaatacgct ccctgaagcg cggaaagtta aatgggttct ggacgtcgat
     5401 ccgattgaag gatagtcccc acgatgcgag gcggatcgta aaattaaaga tccatcacac
     5461 tttttatgaa aattctgtaa ccgcttccac gcactatctg ataaaaatgt tttcgatgag
     5521 tgttaccagg gatagatctg cgccagcagt tcccaggcga ggagaaagag tgaaatcgaa
     5581 caagcaggtt actgccgcta cgatgaagga tgttgcgttg aaggcgaaag tctctacggc
     5641 aaccgtatcc cgcgcgttaa tgaaccccga taaagtctcc cagtcgaccc gtagccgggt
     5701 tgaacaggcc gcgcttgaag tgggttattt cccgcagtcg atggggcgaa atgtaaaacg
     5761 caatgaatcc cgtacgattt tggtgattgt cccggatatt tgcgatccct tcttcagtga
     5821 aattatccgc ggtatcgaag tgaccgcggc agaacagggg tatctggtgc tgattggcga
     5881 ttgtgcccat caaaaccaga aagaaaaaac ctttcttaat ctcatcatca ccaaacagat
     5941 cgacggcatg gtactgctca gttcccgact gccctttgac gccagcgttg aggagcagcg
     6001 caatttgcct ccgatggtga tgtcgaatga gtttgcgccg gagcttgaat tgccgacggt
     6061 acatatcgat aacctgaccg ccgcgttcaa tgccatgaac tacctgttgg atttgggcca
     6121 caagcggatt ggttgtattg cggggccgga agatatgccg ctctgtcact atcgcttaca
     6181 aggttacgta caggcattaa gacgcagtgg cattgtggtc gatccgcatt acatcgcccg
     6241 tggcgacttt acctttgaag ccggggcaaa cgcattaaag cagttgcttg agcaaccgtt
     6301 gccgcctacc gccgtctttt gtcatagcga cgtaatggcg ctgggcgccc tctcctgggc
     6361 caagcgccag ggtctgaaag tgcctgacga tctgtcgatt atcggctttg acaatatcgc
     6421 gctggccgag ttttgcgacc ctccgttgac aaccgtggcg cagccgcgtt ttgacattgg
     6481 tcgcgaggcg atgctgctgt tgctcgatca gatgcagggg caaaatgtga gcagcggctc
     6541 gcgtttaatg gattgcgagc tgattattcg cggttctaca cgcgctttac cctaaagtaa
     6601 atagctttaa gactcacctg tctggtcaaa ggcccgccgc ttcagtaaca tgacgggctg
     6661 acgaacgaat aaatacagcg aaacgatagt ggcacaacga gattatgtac gtcgcggcca
     6721 accggctcct tcgcggcgca aaaagagcac ctcacggaac tcacggaaga agcaaagcaa
     6781 catgcctgcc gtctcgccgg caatggtcgc gattgcggca gccgtccttg tgacctttat
     6841 cggcggtctg tacttcatta ctcaccataa gaaagaagag tccgaaacgc tacaaaacca
     6901 gaaagtcacc ggcaatgggc ttccgccaaa accggaagag cgctggcgtt acatcaaaga
     6961 gctggaaagt cgccagccgg gcgtgcgtac gccaacggaa ccgtccgccg gcggcgaagt
     7021 catgaatccg aatcagctca ccagcgagca gcgtcaactc ctggagcaga tgcaggcgga
     7081 tatgcgtcag cagccgacac aacttaacga agtgccgtgg aacgagcaga cgccagaaca
     7141 acgccagcaa acgctacagc gccagcgtca ggcgcagcag cagcagcagc agcagcagca
     7201 gcagcagcag cagcagtggg ctcaaacgca gcctgttcag caaccacgca cgcagccgcg
     7261 ggtaaacgaa cagccgcaaa cgcgcacggt acagtccgcc ccggcgcaac ccgcgcgcca
     7321 aagtcagccg ccgaagcaga cggcctcgca gcaaccttat caggatttgc tgcaaacgcc
     7381 ggcgcatacc agcgcggcag cgccaaaagc cgcgcccatt acgcgcgcgc ctgaagcgcc
     7441 gaaggcgaca gcagagaaaa aagatgaacg tcgctggatg gtgcaatgtg gttcattcaa
     7501 aggcgccgag caggcagaaa gcgtccgcgc tcagctggcg tttgaaggct ttgactccaa
     7561 aattaccacc aataacggct ggaatcgcgt ggttatcggg ccggtgaaag gtaaagaaaa
     7621 tgccgacagc accattaacc gtctgaagat ggcgggccat acaaactgca ttcgactcgc
     7681 caccgggggt tgaaaccctc aaaatctccc ccatctatac ttgcattatg ccccgtacgc
     7741 cgtacggggc cgcaattcag cattagtaac caaggggtct gctcgtgaca acaatagtaa
     7801 gcgtacgccg taacggccac gtggtaatcg ccggtgatgg tcaggccaca ctgggtaaca
     7861 cagtaatgaa aggcaacgtg aagaaagtcc gccgcctcta caacgacaag gtcattgcgg
     7921 gctttgcggg cggtactgct gatgcattca cgctgttcga gctgtttgaa cgtaaactgg
     7981 aaatgcatca ggggcacctg gtcaaagccg ccgttgaact ggcgaaagac tggcgtaccg
     8041 accgtatgct acgcaaactg gaagcgttgc tggccgtcgc ggatgaaacc gcttcgctca
     8101 tcatcacggg taacggcgat gtcgtgcaac ctgaaaacga tttaattgct atcggctccg
     8161 gcggtcctta tgcccaggct gccgctcgcg ctctgttgga aaataccgag ctcggcgcgc
     8221 gcgaaattgc tgaaaaggcg ttggatattg caggcgatat ctgcatttac accaaccatt
     8281 tccacaccat tgaagaattg accgccaaag cgtaaggacc tctcatgtct gaaatgaccc
     8341 cacgcgaaat tgtcagcgaa ctgaacaaac acattatcgg ccaggataac gcaaagcgtt
     8401 ccgtggcgat tgcattgcgt aaccgctggc gtcgtatgca gcttgatgaa gagctgcgcc
     8461 acgaagtaac gccgaaaaat attctgatga ttggcccgac cggcgtcggt aaaaccgaaa
     8521 tcgcccgtcg tctggcaaaa ctcgccaacg cgccgttcat taaagtcgaa gccaccaaat
     8581 tcaccgaagt gggctatgtc gggaaagaag tggactctat catccgcgat ctgaccgatg
     8641 ccgctgtgaa aatggttcgc gtacaggcta tcgagaaaaa ccgctatcgt gcggaagagt
     8701 tggcggaaga gcgtattctc gacgtactga tcccacccgc aaaaaataac tggggccagg
     8761 ccgaacagca gcaggagcct tctgccgccc gtcaaacgtt ccgcaaaaaa ctgcgcgaag
     8821 gccagctcga cgataaagag atcgagatta acctcgccgc cgcgccgatg ggcgtagaga
     8881 ttatggcgcc tccgggcatg gaggagatga ccagccagtt gcagtctata ttccagaacc
     8941 taggcggtca gaaacagaaa ccgcgtaagc tgaaaattaa agacgcgatg aaactgttgg
     9001 ttgaagaaga agctgctaag ctggtcaacc cggaagagct gaaacaggac gctatcgacg
     9061 cggttgaaca gcacggcatc gtgtttatcg atgaaattga caaaatttgt aagcgtggcg
     9121 aaacctccgg cccggatgtt tcacgcgaag gcgtacagcg cgacttactg ccgctggtag
     9181 aaggctgcac ggtttcgacc aaacacggga tggtcaaaac ggatcatatt ctgtttatcg
     9241 cctctggcgc gttccaggtg gcgaagccgt ctgatctgat cccggaactg cagggccgtc
     9301 tgccgattcg cgttgaactt caggcgctga ccaccagcga tttcgaacgc attttgaccg
     9361 agccaaacgc ctccgtcact gtgcagtata aagcgctgat ggcaactgaa ggcgtcaata
     9421 tcgagttcac cgattccggt attaaacgta ttgccgaagc cgcctggcag gttaacgaaa
     9481 ccaccgaaaa catcggcgcg cgccgtctgc ataccgtact ggagcgtctg atggaagaaa
     9541 tttcctataa cgccagcgat ttgcacggcc aaaacatcac aattgatgcg gaatatgtga
     9601 gcaaacatct ggatgcgctg gtcgcagatg aagatctaag ccgttttatc ttataatcgc
     9661 gtccaatgca ttttcatcac tgttgatggg gctgaaaagc cccattttta ttggcgctaa
     9721 atatgactga acaacaacaa attagccgca cccaggcctg gctggaaagc ttacgaccca
     9781 aaaccttacc tctcgccttc gcggcgatta tcgtcggtac ggccctggca tggtggcaag
     9841 gctatttcga tcctctggtc gcactgctgg cccttatcac cgccgggctg ttgcaaattt
     9901 tatccaacct cgccaacgat tacggcgacg ctgtcaaagg cagtgataaa ccggatcgca
     9961 tcggaccgct gcgggggatg caaaaaggcg tcatcaccca gcaggagatg aagcgggcgt
    10021 taatcattac cgtcgtgctg atctgtatct ccggactggc gctggtggcg gtcgcgtgcc
    10081 atacgttaac cgattttgtc ggcttcctga ttttgggcgg gctgtcgatt atcgccgcca
    10141 tcacctacac cgtgggtaat cggccctacg gttatatcgg gctgggtgat atctctgtcc
    10201 tggtattctt tggctggcta agtgtcatgg ggagctggta tctccaggcg catacgctga
    10261 ttccggcgct gattctcccg gccaccgcct gcggtttact ggcgacggcg gtgctgaata
    10321 ttaataacct gcgcgatatt aatagcgaca gagagaacgg caaaaacacc cttgtggtac
    10381 gacttggcga tgtcaacgcg cgtcgttatc acgcctgcct gttgctaggc gcgctgctct
    10441 gtctggcgct gtttaatctg ctctcgctac acagtccgtg gggatggttg tttattctgg
    10501 ccgcgccctt gctcattaaa caagcgcgct acgtaatgcg cgaaagggag cctgcggcaa
    10561 tgcgcccgat gcttgaacgt accgttaaag gcgcgttgtt aaccaacctg ttatttgtga
    10621 ttgggatact cttaagtcag tgggccgttt aactgacaaa tatcaattaa caattgatga
    10681 ttttgccaac agtatactta gcgcgatata ctaaaaattc tcgcagcaac tgaacgttaa
    10741 gcctatgaaa tacgatactt ccgagctttg tgacatctat caggaagatg tcaacgtcgt
    10801 ggaaccgctg ttctctaatt ttggagggcg gtcgtcgttt ggcggacaaa tcatcacggt
    10861 aaaatgtttc gaggacaacg ggttgctgta cgatctgctc gaacaaaatg gccgtggtcg
    10921 ggttctgctg gtcgatggcg gcggttctgt ccgtcgtgca ttagttgatg cggagctggc
    10981 gcgtctggcc acgcaaaatg aatgggaagg gctggttatc tatggcgcgg tgcgtcaggt
    11041 ggacgatctg gaagagctgg atatcggcat tcaggcgatc gccgccattc cggttggcgc
    11101 cgcaggtgaa ggcattgggg aaagcgatgt gcgcgtcaat ttcggcggcg tgacgttctt
    11161 ctccggcgat catctctatg ccgacaacac cgggattatc ctttccgaag acccgcttga
    11221 tatcgagtga tcaaaaaagg cgccgtaagg cgcctttttt atgcgttgtc gctgattgcc
    11281 ggatgtcggc ttacgcctta tccggcccac cggtatccgc attctaaatc ctctatagat
    11341 ttcgcgtcag ggcaaggcgg caagaaagtg aatccccagg agcataggcc actatgtgac
    11401 tggggtgaac gcacgcagcc aacgccgcca taacgtgaaa tatgacgagg attagacttc
    11461 ttccatacga ccaagcagcg cctgtaaacg ttcctgccag ccgctctgct gttccttcag
    11521 aaaattattt tcacgctcga gttcttcacg ctgatgctgt gcagactgca cttcctgcgt
    11581 caggctgttg ttcttttctt tcagctcttc aatttccatc tgtaacaggg tgatggtgtc
    11641 aatcgcctgc tgtacttttg cttccagttt ctcaaacact tctaaagaca tgatcttacc
    11701 tctcctgaat tgcaaggcga cgcttcacgt aaacgcgcac aatatatagt atcgattgta
    11761 tgaagccccg ctctcgctgt ccagcgacat accgcgtaga tcgcggtttg cagcaatttt
    11821 catccatctc ctggtaacat tcattcaata acttaaaagt gttaacatat tggttaatga
    11881 aatgattcaa ttcactctct tctgctgtct caaaatgcgc ctcatggcgc gataacgctc
    11941 attttattga cgcagtacac acattttgat ttcgatattt ctcgtttttg ctcgttagcg
    12001 ataaattaac agtgtgccta cagggcatcg tggatgtcca tgacctcctc gcataccaat
    12061 aatcattaca tactcttcag gatccgatta tgagtcaaac atcaacctta aaaggccagt
    12121 gcattgctga attcctcggt accgggttgt tgattttttt cggggtgggt tgtgtcgctg
    12181 cgcttaaagt tgccggagct acttttggac agtgggaaat cagcgtcatc tggggtctgg
    12241 gagtagcgat ggctatctac ctgacggcag gtgtttctgg cgcacacctg aacccggcag
    12301 tgaccatcgc actctggcta tttgcctgtt tcgacaaacg taaagttgtt ccttttatta
    12361 tttctcaagt tgccggcgcc ttttgcgcag cggcgttagt ttacgggctt tattacaatc
    12421 tttttgtgga cttcgaacaa acccaccata tcgtccgtgg cagcgttgaa agtctcgagc
    12481 tcgcaggcat tttctcaact tacccgaatc ctcatatcaa ttttgtgcag gccttcgcgg
    12541 ttgaaatggt gattaccgct attctgatgg ggctgattct ggcgctgacc gacgacggta
    12601 acggcgtacc tcgcggtccg cttgcgccac tgctcattgg tttactgatc gccgttatcg
    12661 gtgcctctat ggggccgttg accgggtttg cgatgaatcc ggcgcgtgac tttggcccca
    12721 aaatgttcgc cgggcttgcc ggctggggtg aaattgcgtt taccggcggt agagacattc
    12781 cttacttcct ggtgccactg tttggcccca tcgtcggcgc cattctgggc gcgtttgctt
    12841 atcgcaaatt tattggccgt catttgccgt gcgatatctg cgtcgtggaa gagaaggact
    12901 ccaccgcggc cacacaacaa aatgcttcgc tgtaatctga ttacgggaca aaattatgac
    12961 tgaaaaatat atcgttgcgc tcgaccaggg taccaccagc tcccgcgcgg tcgttatgga
    13021 tcatgacgcg aatatcgtca gcgtatcaca gcgtgaattt gagcaaattt atcctaagcc
    13081 aggctgggta gaacacgacc cgatggaaat ttgggcgtct caaagctcaa cgctggtaga
    13141 agtgctggct aaggccgata tcagttccga tcagattgcc gctatcggta tcaccaacca
    13201 acgtgaaacc gcgatcgtct gggaacgtga aaccggcaaa ccgatataca acgctattgt
    13261 ctggcagtgc cgtcgtaccg ccaatatttg cgaacagctt aaacgcgacg gcctggaaga
    13321 ttacatccgc gacaataccg gtctggtcgt cgacccgtac ttctctggca ctaaagtgaa
    13381 atggatcctt gaccatgtgg aaggttcgcg cgaacgcgcg aagcgtggcg agctgctgtt
    13441 cggtacggtg gatacctggc ttatctggaa gatgacgcag ggccgcgtcc acgttacgga
    13501 ttacaccaac gcctcacgaa ccatgctgtt caacatccat gatttggact gggacgataa
    13561 aatgctggac gtgctggata tcccacgcgc gatgctgccc caggtacgta aatcctccga
    13621 agtctacggc cagaccaata ttggcggtaa aggcggtaca cgtattccta tcgccgggat
    13681 tgccggggat cagcaggccg cgctcttcgg ccaactgtgc gtaaaggaag gaatggcaaa
    13741 gaacacctac ggcaccggct gctttatgct gatgaacacc ggcgagaaag cggtaaaatc
    13801 ggaaaacggc ctgctgacca ccatcgcctg cggcccaagc ggcgaagtca actatgcgct
    13861 ggaaggtgcg gtgtttatgg cgggagcgtc cattcaatgg ctgcgtgatg aaatgaagct
    13921 catcagcgac gcattcgact ccgaatattt cgccacgaaa gtgaaagata ccaacggtgt
    13981 ctacgtggtt ccggccttca ccggtctggg cgcgccgtac tgggatccgt atgcccgcgg
    14041 cgccattttt ggcctgaccc gcggcgtgaa ctctaatcac attatccgcg cgacgctcga
    14101 atccatcgct taccagaccc gcgacgtact ggaagcgatg caggccgact ccggtatccg
    14161 cctgcacgct ctgcgtgtgg acggcggcgc agtggccaac aacttcctga tgcagttcca
    14221 gtcagatatt ctcggcacgc gggtggaacg cccggaagtg cgcgaagtga ccgcgctggg
    14281 cgccgcctat ctggctggcc tggccgtcgg ttactggcag aacctggacg agctgcagga
    14341 aaaagccgtc attgagcgag aattccgccc cggcattgaa accaccgagc gtaactaccg
    14401 ttacagcggc tggaagaaag cggttaaacg cgcaatggcg tgggaagagc acgacaagta
    14461 aggtcgccat ccggcaaaat ctttgtgcgg aggcaactcc gcacacacat caattattcc
    14521 ctccctcccc tgtgctacac tgcgcgccac tcctttttgc tacgagtttg ttatgagacg
    14581 agaacttgcc atcgaatttt cccgtgtgac cgaagcggcg gcgctggctg gctacaaatg
    14641 gctgggacgc ggcgataaaa ataccgcgga cggcgcggcg gtcaacgcca tgcgtatcat
    14701 gctcaaccag gtcaacattg acggcaccat cgtgattggc gaaggcgaaa tcgacgaggc
    14761 cccgatgctc tatatcggcg agaaagtcgg taccggccac ggcgatgcgg tagatatcgc
    14821 cgtcgatccg attgagggca cgcgcatgac agcgatgggt caggcgaacg cgctggcggt
    14881 actggcggtc ggcgataaag gctgcttcct gaatgcgccc gatatgtata tggaaaaact
    14941 gattgtcggt ccgggcgcca aaggggcgat cgatctcaat ctgccgctgg cggataacct
    15001 gcgcaacatc gcggatgcgc tgggtaaacc gcttggcgat ctgaccgtga ccattctggc
    15061 aaaaccgcgt catgacgagg ttatcgcaga gatggccaaa ctgggcgtac gcgtgtttgc
    15121 cattcctgac ggcgacgtcg cggcctcaat tctgacctgt atgccggata gcgaagtcga
    15181 cgtgctgtac gggattggcg gcgcgccaga aggcgtggta tccgcagcgg tgatccgcgc
    15241 gctggacggc gatatgcagg gacgtctgct ggcgcgccat gacgtgaaag gcgacagcga
    15301 agaaaaccgc cgcattggcg aacaggaact ggcgcgctgc aaagcaatgg ggattgaagc
    15361 gggcaaggcg ttatgcctgg gcgacatggc gcgtagcgat aacgttattt tctctgcgac
    15421 cggcatcacg aaaggcgatc tgctggaagg aattagccga aaaggccata tcgccacgac
    15481 ggaaacgctg ctgatccgcg gcaaatcacg caccatccgc cgcattcagt ctatccacta
    15541 tcttgatcgt aaagatcctg atgtgcaggc gcatatcctc tagcgcattt gttagttaga
    15601 gccttccagc ctcgcggggc tggaaatctt tctcctgacg aacgaagata aggttagcga
    15661 ttcagaacag gagaaaacca tggccgattg ggtaacaggt aaagtcacta aggtgcaaaa
    15721 ctggactgac gcactgttca gcctgaccgt tcacgccccc attaatcctt ttactgcagg
    15781 ccaatttacc aaactcggac tggagatcga tggcgagcgc gttcagcgcg cgtattccta
    15841 tgtgaatgcg cctgacaatc cgaatttaga gttttatctg gtgacggttc cgcaaggaaa
    15901 gctcagcccg cggctggcgg cgctaaaacc tggcgatgag gtacaagtgg tcagcgacgc
    15961 gtcgggtttc tttgtactgg atgaagtgcc tgactgcgag acgctatgga tgctggcgac
    16021 cggaaccgct attggcccgt atttgtctat tctgcaatat ggccaggatg tcacgcgctt
    16081 taaaaatctg gtcttagtcc acgccgcacg cttcgccgcc gatttaagct atctgccgct
    16141 aatgctggaa ctgcaacagc gttatgaagg caagctgcgc atccaaacgg tggtcagccg
    16201 ggagagcgtg ccaggctcgc ttaccgggcg cgtgcctgcg ctcattgaaa acggcgagct
    16261 ggaaaaagcc gttggattac cgatggataa agagaccagc cacgtcatgc tgtgcgggaa
    16321 cccgcagatg gtgcgcgata cgcagcaact gctgaaagag acccgacaga tgactaaaca
    16381 tctgcgccgc cgaccggggc atatgacggc tgaacattac tggtgatgtt ttaccgaatg
    16441 gcagctaggg cttatccggc ctgcaaatca tcaccaatct gtaggcccgg taagcgtcag
    16501 cgccaccggg caaattacgg tttaccgccc gtttacggtt ctgccttaaa cttcacgtcc
    16561 tgtgtcgctt tcccaaactt attttccccc tgaacaccga caaacgcgcc cagatcgata
    16621 agcatcatca ccaggatcag cgtcggaata aatcgcccga cgacccactg ccacatcccc
    16681 ggcaacatca cccagtttcc ggccagcagc atccacgcca gaatcattag caacgcccac
    16741 gcgccggaac gtccccggtc atgcagacgt ttgaccatga cggcggcggt cggccacagc
    16801 aggcacacca ggcaaaatgc cgccgtttgg atatcaagca ggtttttccc cgccagcgaa
    16861 aatagcgcca gcatcccggc aaaccagagg ccgatccaaa tccagaaatc acggcgtccg
    16921 atacgccctt taaatgagaa taaccattgc tgtatggtca tgtaagttcc ttatattttg
    16981 ccttccgcta cagtttaccc ttttgacaag cccgacagtt atcgttttaa tcgtgagcag
    17041 tcctaacgaa aggtaagatt gatgaagcca ggatgtactc tgtttttact gttgttttct
    17101 gctctcaccg ccagcataac ggcgcacgcg cagctctctt catcgaccac gacagcgccc
    17161 tatctgctgg cgggctcgcc aacctttgat ctttctatta gccagtttcg tgagaacttt
    17221 aaccgccaga atcccgatct gccgctcaat gaatttcgcg ccattgagaa tagccgcgat
    17281 aaggcgaatc tgacccgcgc cgccagtaag attaacgaaa atctgtatgc ctccacggcg
    17341 ctggagcgcg gtacgctcaa agtgaaaagt atgcagatta cctggctgcc cattcagggg
    17401 ccggaacaga aagcggcgaa agcgaaagcg ctggaatata tggccgccat tattcgcact
    17461 gtcgccccgt tactgacaaa agagcaaagc cagaaaaaac tgcaaaagat gcttatcgcc
    17521 ggtaaaggta aacactatta cgccgagacc gaaggcgcgg tacgttatgt tgtcgcagat
    17581 aacggcgaaa aggggctgac cttcgcggtt gaaccgatta agctggcgtt atctgaaaat
    17641 ctggaagggg cgaattgatg acaaaaagca aagcctttcc ggggatgaat ctctatactg
    17701 tttcacagac catgctgctc tgacgagcgg ccatcttcct taattcgctg actaagcgtg
    17761 gagaaatgaa atgcgacatc ctttagtgat gggtaactgg aaactgaacg gcagccgcca
    17821 catggtaaac gaactggtgg ctaacctgcg taaagaactg acgggcgtag caggctgcga
    17881 cgtggcaatc gctccgccgg aaatgtatat cgatctggcg aaacgcgctg ctgccggcag
    17941 ccacatcatg ctgggcgcgc agaacgttga tctgaatctg tctggcgcat tcaccggtga
    18001 aacttcggct gaaatgctga aggatatcgg cgcgcagtac attattatcg gccactccga
    18061 gcgtcgtact tatcacaaag aatctgacga gctgatcgcc aaaaaattcg ccgtactgaa
    18121 agaacaaggt ctgacgccgg tactgtgcat cggtgaaacc gaagcggaaa acgaagcggg
    18181 caaaacagaa gaagtgtgcg cacgccagat cgacacggta ctgaaaacgc agggcgcggc
    18241 agcctttgaa ggcgcggtta tcgcttacga acccgtatgg gcgatcggta ccggtaaatc
    18301 tgcaactcct gcgcaggctc aggcagttca caaattcatc cgtgaccaca ttgctaaagc
    18361 tgacgcgaaa atcgctgaac aggttattat ccagtacggc ggttctgtta atgcgtccaa
    18421 cgcagccgaa ctgttcgcgc agccggacat cgacggcgca ctggtaggcg gcgcttctct
    18481 gaaagctgac gccttcgccg tgatcgtgaa agcagcagaa gctgctaaac aggcttaatt
    18541 gccaatcaat gtctgatggc gctgcgctta tcaggcctac cagccgagtg cttatgtagg
    18601 cctgataagg taaagccgcc atccggcatt tatgctgtgg agggtaagaa agtagtatcc
    18661 ccggcaacct taaacatcgc cctccagctc cgcgtattct caaccagccg atcatcacga
    18721 aataacgcac taccagaaac aacacgatcg atgccctgtg caatcagcga aggcaactga
    18781 tcctgcgtta acgacccatc aataacgata attttacctt cgcgtttatc accaagtaga
    18841 cagagaagct gtgccacgcg ctcgtacaaa tcactggagc gcattttact gccgtatcca
    18901 gggttcactg ccagtagttg aataacctca acgtcgctca gaatagggat aatgacatcc
    18961 agaggcgttg ccgggcataa actaatcccc cggatcaccg gcatttcacc gtcaataacg
    19021 ggcacggtct gctgaccaag ccagcttagc gtatgatgca gatgaatatc gccttcagcc
    19081 tgaagcgtga tgcagtgtgc gcccgctttc acgcaggctt gcgccgccgc ccattgatcc
    19141 gctaccatca aatgaacatc tttgataaaa gtttgcggca gttgcccaac tgcccatggc
    19201 ccaacggtaa actgtgggca aaattgacca tccatcaaat ccaaatgcaa cagcggctgg
    19261 tttaacgctt ccaactgttg cagatagcga tgcaacgcaa tccactgccc tgccagaata
    19321 cccacactaa gcggatatga cgctaacaat gccacacatg cttcgcgcgt taatccggca
    19381 aactggctgt tcatgagcgc tccttaaggc atcaaaccca taaaaacttt ttttgtccgc
    19441 ggaccggtca tcaacggttc aagctgctcc acgcaagttt tatagtgtgg cgttgtcttg
    19501 tgaaaagcga cggcctgttc atcaacgtag gcttcataaa tataaaatcg cgtaggcacc
    19561 tgcggatcct gcagaacatc aaaacgcaag ttacccggct ctttaattga gcccagatga
    19621 ttctgccgaa aaacatcgat aaattgttca accttgtcat catgaacgtt aatttcaacc
    19681 agcgtaacgt gcatcattaa ccccctgatt attccaaata aaataacagt catccccatc
    19741 tcctcgcatc ggtaaaagat ggggaagcga tctcatttaa cctttctcac tcaaaaacag
    19801 ctcataagca cgctctgctg tttcgttatg atgaacgaca gcatgtaccg ctttaatcat
    19861 ggctaccgga tcttctgact ggaatatatt acgccccata tctacgccag aagccccctg
    19921 gtcaatcgcc tgatagcaca tttccaatgc ttcacgttca ggcagttttt taccgccggc
    19981 gatgacaatc ggcaccggac aacctgccgc aatacgctca aaacctttat cgacataata
    20041 cgttttgata atttgcgccc ccatttccgc agcgatacgc gttgccagtg aaaaataacg
    20101 ctggtcgcga gccatatctt tacccacccc ggtcactgcc attattggca tcccgacgcg
    20161 taacccggca tcaatcagtt gaataatatt tttaatcgac tgatgttcat gttcactacc
    20221 aatataaacc tgtgcggcag cagcacagct attcaaccgc acagcgtcat ccatcgccac
    20281 cgcaaccgcc tcattgctta attcagtgag aatagaattt gccccggacg cgcgtaaaac
    20341 gactggttta ttgattgccg gaggtaccac actgcgtaat atgccgcgag tacacattaa
    20401 gacatcagca tattcaaaga gcggcgcaat attgatatca atacgctcaa gtccggttgt
    20461 cggcccctgg aaatatccat ggtcaaaggc cagcatgacc gttttcctgg tcctgggatt
    20521 aaaaatcctc gccagtctgg actgcattcc ccaatccagc gcgccacagc cttttaatga
    20581 gaacaaagtg ttagtttgtg gtttatcggt gtgaaaatct ttgccatctt taatatcatc
    20641 taaatcagcc attctttact ccgtcgatac ataacagtta tcagaaatca tatttgtcga
    20701 tattgtcttt gttgaaaatg acacgctctg gcaataacac aatgccgtta ccttttgcct
    20761 catagtgata tccctgctca ctattaggtg aaacggtgac tttgccgatg ccgggaatat
    20821 ccagtgaatc accgacattc attggcatat ttttcagcaa cgcgttggcg acatatacgg
    20881 aaatttttcc ctgttggacg acatcccaca ggccaaactc tttaacagtg ccgcgctgaa
    20941 cataagggcg cattacattc ggcgtactaa aaccaacaat cgcgagatta ttacgtttaa
    21001 ggttctccgc cgcctgtgcc gcagcaggta aagcgttagc gtcaggcgcg atgatggcat
    21061 ccagatcggg atacgctttg atgatacctt ccgccgtctg gagcgatttc gtggcatcgt
    21121 tatagccaaa ctgggtagtg actatctccc accctggatg ttcctggcta attttggctt
    21181 tagcttcttt tacccactgg ttctggtcgg tcaccgttgg gctggaatag aagaaagcga
    21241 ctttcgcttt ctctttgtcc acctgatgag cggccatctc taccagcatg ctgccgagct
    21301 gttttggcgt cccttgattg atatagtaag aacggcactc cggcttggta tcggaatccc
    21361 aggttaatat tttcacgcct ctttgcattg cccgcttcaa cgccgggcac aggccatcag
    21421 gcgaaacggc agaaacgata atggcgtcat acccctgatt gacaaagtta ttcaccagtt
    21481 gaacctggcc tgagacgctg ggctctgtag ggccatcgta agttacgtca atgcccagcg
    21541 cttttcccgc ttcctgcgcg ccattgccgc cgctggtaaa aaagcccacg ccaaccagtt
    21601 tgggaataaa agcaatccgc tctgccgcct gcacggtcat taccgcagat gccagaccaa
    21661 acgcagtgag taaggcgatc attttaatgc tgtgtcttgc catttttttc tccataaatt
    21721 tcaaaaggaa atcatgcctg atgcgcattg cgacggcgtg agtaccattc aaggatttgg
    21781 tgacgatgca aactgacgga acgaccaacg acaacaacaa tgagaagcgc accggacaat
    21841 gcgctggaaa tttgattcgg cactccggcc atctgtagcc cctgctgtaa aaatcccacc
    21901 agcagcgccg ccaacgcgga ccccataatc gacccggagc cgccataaat attggcgcct
    21961 cccagcacaa ccgccgtaat ggtcggcatc aggaaagagg cgcccagatc cgaacgtgcg
    22021 gagccaaagt aagaaaccag taatacggcg gcgatcgcgg aggcgcatcc ggtcatggca
    22081 tacacggtat acaacgtgcg attcaccggg atcgcgctgt actgcgcgac acgtgcgtcc
    22141 catatgcgtg cgatgcatga gcagccagaa aaacagacag cacacaagaa aaaaaataag
    22201 cggcatagga ataccaagaa atgaaatatt ggcaaagtca gtgaacgctg tgggaaatcc
    22261 accaatacct tcataacccg tggcgccagc cataccagat aacaataatg cgctaccacc
    22321 aaataaatac atggttccca gggtaatcac caacgggttt acgccggtat aaataataag
    22381 tccggcattt atcagcccac atattgcgcc gagtagtagg gtaataataa tcgctaaagg
    22441 tagcggcata ccgagctgaa acagcacacc cagggtaatc gcgcatagcc cgattgtaga
    22501 accaaatgaa atatccatac caccgctgac aataaccatt gttagcggca aagcgacaat
    22561 accgatacaa ataaaatcgc tagtgctaaa aagtaagaca ttaatatcta ataaacgtgg
    22621 attaatcaga ccgaaagcca gaatttcaaa gatcaataag gctgccagcg caatttccca
    22681 gctatagcgt cgccatggat tcatcatgcc acctctttgt ttttattctg ttgtgcgtgc
    22741 gtttttgctt ccgcctgtag tggagtgggt ggtgatataa aacgggcata tttctggcgg
    22801 cgcagattgc gttgtaatgc gcaacgcagc cgcccatcga ataccagtac gcccaacaat
    22861 accaggccag caataaaatc gttccaccag gcggggatgc gcagcagcac taacacacta
    22921 tcgatttgcg taagaaaata agcgccgaga atagcgccga tgaccgtgcc tgacccgcct
    22981 aacaggctaa ttccccccaa tacgcaggcc gcgatggctt tcatttccag ccccgtgccg
    23041 gtttgattgg gaatgaagcc aatctgcgag gcaaacacga ttccagccaa tgccgccata
    23101 ccgccattaa gtgaaaatgc catgatgcgt accatctcgg tacggacacc caattgccgg
    23161 gcgccctgca ggttatcgcc ggtggcgtaa aaattgcggc caaaggcggt tttcgccagg
    23221 agccaggcca taagcagcgc taacaccagg gtaaaccagc cgattgcgga aattcccaga
    23281 aacaccggag cagagagttg ctttaagcct gcgggtaatc cttcaatcca ttttccccct
    23341 gtccatagca gcatgatccc acgatacaag cccagcgttc ccagcgtggc gacaatggcg
    23401 ggtatcttca accaggcaac cagtacgcca ttaaaaaatc cggcgacaat tcctaatatt
    23461 agtgtggcca ggcaggcgac cggcaggcta tagccggcgt ttaacattac tcccagcaat
    23521 accgcgcaca ttcctgtcgt cgagcccacc gatacatcaa tattgcgggt gagcattacc
    23581 atcgtcgcgc caatcgccaa cagcatcaaa atttgcgcgc tactgaaaac cattgtcagc
    23641 gtttgcacgc tcaaatactg gctatccagc gcgccaagaa acacgaataa acagactatt
    23701 gccagcagtg ccgtcgcttc ccggttattt tggatgaatt tcaacatgtt gcctccgacg
    23761 caccatgttc gccaaacgca acgtgcatga tggtatcaac gttaatttcc tcgccgcata
    23821 acgcaggccc ccccagttcc ccctggtgca tgacatatac gcgatcggcc atctgctcta
    23881 tctcttccag atcggaggaa ataaacagca ccgcgacatt ttgttgcgcg atactgcgca
    23941 acagctgata aatatcgctg cgggcggaga catcgacacc gcgggtcggt tcatcgacaa
    24001 tcagtaattg cggagaggcc tccaggcatt tggcaatcaa tactttttgc tggttaccgc
    24061 cggataaagt acgcgccgcc tgttcggcat tattgagttt gatatttaac gcgcggtggt
    24121 aacgttcaag ggtggcgtta tcccgctggg gctttatcca aaatcctttt tggttgtggg
    24181 tcagcgaaca gacattccat gccagggaag cgtcaagata cagcccggat gactgccgat
    24241 cttccggcaa atagaccagg ccgagctgca accgctgttg ggttgtcagg gcgttaattt
    24301 cttcaccatt gaacagcatc cgccccgcat tgaccggtct aataccgtac agcgtttcag
    24361 ccaattctgt gcgtcccgcg ccgaccaacc cggccaaacc aaggatttcg cctgcccgca
    24421 cctcaaggtt gatattcata aaaccttcgc ccgtcagtga ctccagcgct aataccgtcg
    24481 cgccgcgttc gttctgcggg cggctgccag gcaattccag ccacaacttt tgactcgcgg
    24541 aaagactgac gccctgcgtt gccggggtga tagcttgaat aatctcgtcg gtagaaaggt
    24601 catgcgtttt tctgaataat gcgattttac cgtcacgcat cacgctaacg cagtgagcta
    24661 actgtctaat ttctggcagc ttatgagaaa taaatacaat tccgacaccc tttttcagca
    24721 actcttgcag acgcgtaaat aaccggtcag tttcggctgg cgttaacgac gccgtgggct
    24781 catcaagaat taagattcgc gagtcgcgca tcaagccgcg cataatttca acgatctggc
    24841 ggtctgcaac atcaagcgta cccgcagcgc tcgccggatc gagttggcat cccatcgcct
    24901 ttaatagctg ctgcattttt tccgtggagg cctgacgtcc ctgcaagcca aacaagatat
    24961 tttcccgcac agataaactc ggaaataaca gaggctcctg gggaaccagg taaatgccat
    25021 actggtgcgc cttcagaggc gttaaatgac tgcaacgcac accagcaata tcgatagtcc
    25081 ctccatctgg cgggactata ccggcaataa tcttcattaa tgttgattta cccgcaccat
    25141 tgccgccaag caatgcgtgc acctctcccg catgcagagt aaagtcaatt ccctttagta
    25201 cttcgacgcc ggaataactt ttataaatgt tctgcacaca aatcagaggg gatgcagtat
    25261 tgtgactgat ttgcatgttg cctccgctcc ctcaatgttg actgacggga ctgaacaaat
    25321 gttttttgaa aaagaaattg ttcaaaacgg tagtagttat ttggtcaaaa aactctcatc
    25381 cagatcacgt tttctgaata aatgaatttt tagatgataa atgttcagat ttggcgcgtt
    25441 tttgtggcgt taatcacggt tatttcggag tgataactga acaattgtgt taatgattta
    25501 gaaatgttca aagtaaagcc aggttatgac aatgagcgat aatacgttgg tatctgatta
    25561 tggaatgtgc gaagaagagc aggtggcgcg tattgcctgg ttctactatc acgatggatt
    25621 gacgcagagt gaaatcagcg agcgtctggg gctaacccgg ctaaaggttt ctcgtctgct
    25681 ggagaaaggg catcagtccg gtattattcg cgtacaaatc aactcccgtt tcgaagggtg
    25741 tcttgagtat gaaaatgcct tgcgtaacca cttcgcattg cagaatatcc gcgtgctgcc
    25801 ggcattaccc gatgccgata ttggtctgcg cttaggaatc ggcgccgccc atatgttgat
    25861 ggagtcactg cggccacagc aactgctggc cgtcggcttt ggcgaagcca cgatgaccac
    25921 attaaaacgc ctcagcggat ttatctcggc gcaacaaatc cgactggtca cgttatccgg
    25981 cggcgtgggg ccgtatatga ccggaatagg ccagcttgat gccgcttgta gcgtaagtat
    26041 tatgcccgcg ccgctgcgcg catcatcgca ggaaattgcc tgcacgctgc gcaatgaaaa
    26101 tagcgtgcgg gatgtgatgc tcacagcgca agctgccgat gccgccatcg tggggattgg
    26161 ggcaattaac cagaaagatc aagccagtat cttaaaatcc ggctatatca ctcagggtga
    26221 acaactcatg attggccgca aaggcgcagt aggcgatatt ctgggctatt tttttgatgc
    26281 tcatggcgaa attattccag acatcaaaat ccataacgaa ttaattggcc tgaagttaaa
    26341 ttcactttcc acgatcccaa ctgtgattgg cgtcgccggc ggcgaacaaa aagcagaagc
    26401 tattattgcc gctatgcgcg gtaactatat caatgcgctg gttaccgatc agaaaaccgc
    26461 agggaaaata attcaactta ttgaaaaata aaaaataaaa taacacttac ctcaattcaa
    26521 taaacaataa ctgacaggat tttatgtaac gatgtaaaaa tagccgaggg taaaaaaatg
    26581 gctcgactct gtacccatac tgaatcagga cattacctga tggctcttga cgccggtacc
    26641 ggtagcgtca gagcagtaat ttttgatcta caaggaaagc aaatagctgt cggtcaagcg
    26701 gaatggcagc atctggccgt gccggatgtg cctggttcga tggagtttga tcttgccaaa
    26761 aactggcaac tggcttgcca gtgtatccgt caggcactac agaaagccgc catccctgca
    26821 acggctatcg ctgccgtatc ggcctgttcg atgcgtgaag gcattgttat ttatgacagt
    26881 aacggcgaac ccatttgggc ctgcgctaat gttgacgccc gcgcggcgca cgaagtcagt
    26941 gaattaaaag agctgcacga taacaccttt gaggaggaag tttatcgttg ctccgggcaa
    27001 acgctggcgc tcagcgctat tccgcgtctg ctctggcttg cccaccatcg tccggatatt
    27061 tatcatcgcg cgtcaaccgt cactatgatc agcgactgga tggcctttat gctcagcggc
    27121 gaactggcgg tcgatccctc caacgcaggc acgacggggt tattggatct ggtgacccgc
    27181 aactggaaac gtagtctgtt acagatggcg ggcctgcgtt ctgacattct ctcgccggta
    27241 aaagaaaccg ggacactgct cggtcacatt tcacagaaag cggctgaaca gtgcgacctg
    27301 caagcgggta cgccggtcat cgttggcggc ggcgatgtgc agttaggctg tctggggctg
    27361 ggcgtcgtac gcccggcgca aacggccgtg ctgggcggaa ccttctggca acaggtcgtc
    27421 aatcttcccg cgccggtcac cgacccaaac atgaacgttc gcatcaatcc tcatgtgatc
    27481 cccggtatgg tacaaaccga gtctattagc ttttttactg ggttaacgat gcgttggttc
    27541 cgcgacgcct tttgcgccga ggaaaaacta atcgctgaaa ggttaggtat tgatgcgtat
    27601 tccctgctgg aagatatggc cagccgggtg cctcccggcg cgcacggtgt gatgcccatc
    27661 ttctctgacg ttatgcgttt taaacgctgg taccatgccg cgccgtcgtt tatcaatctg
    27721 tctatcgatc ctgaaaaatg taataaagcg accctatttc gcgcgctgga agagaatgcc
    27781 gccattgttt ccgcctgcaa tttacagcaa attgccgcgt tttccggcgt acaggccgac
    27841 tcgctggttt ttgccggcgg aggatctaaa ggcaaattat ggagccaaat ccttgccgac
    27901 gttacgggac tcaccgttca cgtacctgtc gtcaaagaag ctaccgcgct agggtgcgct
    27961 attgccgcag gcgttggcgt gggtatctgg ccatcgctgg cggaaacggg agaaaagcta
    28021 gtgcgctggg atcgggagca taaacctaat cctgaaaatt tcgctgtcta tcagcaggcc
    28081 agagaaaaat ggcaggccgt ttatcaggat caacgcgcgc tggtcgatgg tggcttaacg
    28141 acatccctct ggaaagcgcc aggcctgtaa caggagaata agcatgcaaa aaacgaatga
    28201 gaagaatcat gaataccgct ttagtgataa tggccctaaa tacttaatcc gtgggccggg
    28261 ctgcgatatg ggcgtcgtca tactacaacc agggcagtca ttccctaacc atcgccataa
    28321 taccgcttgt gaggtttttt ataccctaag cggtgaagtg tgcctgtatc tggaaggaac
    28381 acctcatatc ctgcaaactg gagatgtttt acagtgcgaa ccaggggagg cacattatct
    28441 cattaataac ggcgataagc cctagaaagg cgtgtttatt aaatcgccgc atctggaaaa
    28501 tgacagccac cccgcagatc caccggcctg gtaacgccca cgccatcgcc agattttgcc
    28561 ggatagcgcc acgagagcct tgtccggcct ccaaacggca ttcgttaatg caatatcaag
    28621 ctgtcatttg atgacctgtt ggttcaagat atcacactga tgatcctgaa tttcctcggc
    28681 agaagcgcga ttgaaggtca gtaaattacg ctcggtcgcc agcaggacaa aagagccatc
    28741 gctttggcgt accaccgcca gcgcgctaca tcactgcatc cccgcccgcg caggaacttt
    28801 ccctggtccc atcgccacca cagcagcaaa aaatagcagt gcggtcataa actccggcag
    28861 tagcgaagtc gcccacagaa ggatagtaat gccaacgatg atggaaggga ggatcagagg
    28921 ataggacaac cagagcgaca tacctgtctc ctgacgattt tttcagcaag aatacgacgg
    28981 acagtcaggc aggtaaacgc cagatatagt ggggttatcg caggattaag tggacagatc
    29041 agtgataatg aatttcacca aagtattcag acagcacgta atagcggcaa tactcaaaag
    29101 ggctgtcctt cccggcctga aacgtctgtc tggcgacgga taacagcggt ttattggggg
    29161 cgatttgcaa tttttcgcac aggtcagcgg aaggtaaaat cgcctcaact ttttctatcg
    29221 ccgagtcgct tgtgacgttt aataacgaat aaagcgacgt atgctccagc gcctgcggtg
    29281 tgagttgcag atcgggaaag aagctaagat cgagatagat cttttcatgg ttaaacggac
    29341 ggttattcag gcaacgaata cgcgaaatat agagatagtg atgctgtgcg ggcaggctca
    29401 agccgtctgc ctgagcgtcg cgcgcgcggc gcggcgcgat ttccagaata cggttctcaa
    29461 tcgccacgct ggcgtcctgg agatcgcggg taataccgcg aaacgtgtgc ccgtagctca
    29521 cgccttccgg caccgagcac accaccgaac cactcccgcg ctgcgacgaa ataatgcccg
    29581 cattgattaa ttcgctccag gcctgtttaa ccacaatcag cgagacgttg taggatctgg
    29641 caatctcttt ttgcgtcggt agttggctac ccaaaggcaa agacccgttc tggatctgct
    29701 gacagatgat aaaaaatagt tgcttataaa gcggagtaaa gctcgtttta tcaacctgca
    29761 agctgcgcac ctcacgtctt cgccagcagg ggacgtttta ccgtccccgg cagggtgaag
    29821 tcgctaccct gcgatttgcc tggccagttc tgccaaatcg aaatgattca tacgatccaa
    29881 agtcgttaaa taatcggcgg gaaaagcctc cacgccatgg aatgcgccgg aaatcgcccc
    29941 gaccatggtg gcgacagtat cagtatcatt gccgatatta acgccggaga taatagcatc
    30001 tacggcagaa ttcggacaac acgcgaacag gccaaaggcc gcgggcaccg cttcactcac
    30061 gtgcagcccg gagccaataa tatcggcaat atccactatc gccgtttccc aatggcgatg
    30121 acgtttaccg atatctacgg ccagctcaat gcgtcgggca acggaaggac ctgccaccat
    30181 catcgcccct tgctcctgcg ccagcagata gcccctttgc gcaccgtaaa taccggcggc
    30241 aataatgctg tctgcattgg tctgcgctct taacgcctcg ctggttgccg ccgccatcgc
    30301 cgctgcgccg gacatcgcca gcacgttatt atgcgtaaaa cggcaaatct gcagcgcgca
    30361 gtcaatcgcc gcgtcaatat cacccgggtg cagcaccgcc gctggccaaa tcttcatggc
    30421 ggcgccgttc gttgcctccg cattaccctt attaatgatc tgtaccgact gtttctcgcc
    30481 ttccagctca ccctgtaaag aggcgcggtt atcattgaat attgccttca ttgccgcacg
    30541 cgtcgtcggg ccggtaaagt tggcgtagta cgggtaatcc agccactgct ggaaagcttc
    30601 gcgcatcgct tcgtcgctga cttcacgctg atggcgcagc agcgcatcca tgatgtactt
    30661 cgcctgaata aaatcatccg tgcacatccc cgcttcattg cagcgcccaa acgtgtccgc
    30721 aggcggtttt tgaaaggtcg tcacccagcc gccaaaatag tcttttattt gctgctgggt
    30781 gcgtacttcc gtcgcggctc ccatcgcgtc cgcggcggcg gcgcccacca ggcatcccag
    30841 tattttgttt tgatcaacgt gcatgatgac tccttatttc acggtcatgg cttgtgccag
    30901 cgaatggctg gacagaaaag tgtttagctg gtcgggaaac ggcagagcgg tcattgcgcc
    30961 ttttgccgtc accgccatag cgccgcaggc attggcattg ctgatggctt ccgccagcag
    31021 ggcatgatcc cagcaatttg cgcgggaaag ggtgaacagc aggccgccga caaaagcatc
    31081 gcctgctccg gtggtatcga cgacatcgac gcgtggtgcg ggaaaatgga actccccctc
    31141 ggcggtaatc aacagcgcgc catcggcccc cagcgaaatg atcgtggtgt cacagcctag
    31201 atcgcgcagg taataacgcg catcctgcca gtgactggcc ccgctgagct ggcacagctc
    31261 atctgccgag actttgcaga tagaagccaa cgcggcggac cgggcgatca gttcagggat
    31321 ttcatcggta ttgcgccaca tcttgctgcg taagttgacg tcgaataaca cgtagccacc
    31381 ggcttctcgc atgcgtctcg ccccttccag acatgcttcg cgagcgggac tgtcggtgag
    31441 gccaattgag ctgaagtaaa accattcgtg ctgcctgaac ggcggcaaat cctgcggcga
    31501 aacgtaggta tcagcccccg gatgcaccag ataggtaaag ctgcgttccc cgtcagccgt
    31561 caggttgacg atcagcaccg cgctggtcag ggccgcatcc agccgcagcg aagagacatc
    31621 cacgccgtta tcctgaaaaa cctggcgcag gaaacgaccg gcgtcatcat caccaagaca
    31681 accgataaaa ccgcactccc cgcccagcct ggcaacgcat acccccacgt tcgccgacgc
    31741 tccgccgggg catttcagat agctgttctg tttttccggc accagatcaa cggaggcatc
    31801 gccgataacc caaaccttat tcatggcctt catttgcgcc tccttatgcc tgtttctgcg
    31861 ccagggcgag ctgaatatca cgataatatt cattattaat cagatacttt ttcatcagca
    31921 gcccaaccgc aaggtggaac agagccggaa tgagcgtcat catcagcgca ataccggtga
    31981 gcgaacgcgc gctctgttca acatcggcct gatagccaaa gtggctcagc aggaatccga
    32041 gtatcccgcc cgcgatcccc atcccaaact tctggaagaa gaggatgccg ccaaacgcca
    32101 acccggaaac gcgcagaccg gttttctttt ctccgtaatc caccgcttcg gcgatagagg
    32161 accagaacac cggcatttac atatcgcaga agaaattaat aagaaaatag aacgcaaacg
    32221 ccaggataag attttcacgc ccgacagaga aatacatcag cgcgctcagg ataaaggtaa
    32281 taatctgggt gtagcggaac atcttaattt tgtcccagaa cttggttatc caggtggtgg
    32341 caatcatcgc taaaatagag gcaacgacgc cggtagtcag gaagggtgaa atcaggctat
    32401 ctccgccgtt cagataatac ttggcgtaat aagcggcaac ggaaccgcga ataacataac
    32461 cgcacatcag cagcagaata acaacgccga gaataatcca ctgatcgtta cgtaacagat
    32521 atttaaactg tttccccacc gatagcgagg taatctccgg ctcgctgcgt tcacgcgtgg
    32581 tgagaaaaca gaagataaac agcagcgcac ccattgcccc cattaagccc atcgaaaact
    32641 gatagcccaa agccttatta ccctgcccca gccagacggc aagcatcggt acaacgatag
    32701 tcaccagaaa agcggcaatc ttggtcatca caaagcgata accgttggcg cttaaccgct
    32761 caacggggtc gctggtaatg acgccaatca tcgaaatata aggaatggtg atcgcggtat
    32821 agaccagggt cataagaata taggtgccat aggcccacgc tagcttggcc atataagcca
    32881 tgtcaggcgt aataaacatc aaatacacgg cgaaaccaaa aggaatggca aaccacagca
    32941 gccacgggcg gtaacgtccc cagcgcgtgt tcagtttatc ggtcagaacc cccatggccg
    33001 gatcgataat ggcatcaatc atccgcacaa ccacaaacag tacgccaaca tcagcggcgc
    33061 tcaggccgta gatatcggta tagaaatagg cgaggagcag ctgcatggcg ataatcacaa
    33121 cgtttatcgc catatctccc gcgccgaagc cgattttttc cacgatagaa agtttcatgt
    33181 tgatattcct ttacgcttaa cagcgcaaat ctggtgaaca a
//
LOCUS       DAJVBX010000021        33080 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.021, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000021 DAJVBX010000000
VERSION     DAJVBX010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 33080)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33080)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33080
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.021"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..71)
                     /locus_tag="OPV72_000916"
     CDS             complement(<1..71)
                     /locus_tag="OPV72_000916"
                     /EC_number="4.1.1.112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462263.1"
                     /note="catalyzes the decarboxylation of oxaloacetate to
                     form pyruvate and carbon dioxide; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxaloacetate decarboxylase subunit gamma"
                     /protein_id="HCR9913284.1"
                     /translation="MTNAALLLGEGFTLMLLGMGFVLA"
     gene            complement(227..844)
                     /gene="ttdB"
                     /locus_tag="OPV72_000917"
     CDS             complement(227..844)
                     /gene="ttdB"
                     /locus_tag="OPV72_000917"
                     /EC_number="4.2.1.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L(+)-tartrate dehydratase subunit beta"
                     /protein_id="HCR9913285.1"
                     /translation="MTKKILTTPIKDEDLADIKAGDIIYLNGHIVTCRDVAHRRLIEG
                     GRELPVDVRGGAILHAGPIVRPIKGEDDKFEMVSVGPTTSMRMEKFEKEFIAQTGVKL
                     IVGKGGMGKGTEEGCAEHKALHCVFPAGCAVVAAVCVEEIEDAQWRDLGMPETLWVCR
                     VKEFGPLIVSIDTHGNNLFEQNKIIFNQRKEIVADEICQNVSFIK"
     gene            complement(844..1743)
                     /gene="ttdA"
                     /locus_tag="OPV72_000918"
     CDS             complement(844..1743)
                     /gene="ttdA"
                     /locus_tag="OPV72_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L(+)-tartrate dehydratase subunit alpha"
                     /protein_id="HCR9913286.1"
                     /translation="MSKSEQISHMTDVMAKFVGYTGKVLPDDVTAKLEDLHKKETSKL
                     ADVIFTTMIENQRLAKELDRPSCQDTGVIQFLVECGTNFPLIGELEALLREAVIKATV
                     DSPLRHNSVETFDEYNTGKNVGKGTPTVFWEIVPNSDQCSIYTYMAGGGCSLPGKAMV
                     LMPGAGYEGVTRFVLDVMTSYGLNACPPLLVGVGVATSVETAALLSKKALMRPIGSHN
                     ENERAASLEKMLEDGINKIGLGPQGMSGNTSVMGVNIENTARHPSTIGVAVNVGCWSH
                     RKGHIVFDKDLNYTITSHSGVNF"
     gene            complement(1776..3044)
                     /locus_tag="OPV72_000919"
     CDS             complement(1776..3044)
                     /locus_tag="OPV72_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13/DASS family transporter"
                     /protein_id="HCR9913287.1"
                     /translation="MEPITLTLCLLVFAIVMFVWEKVPLAVTSMIVCVALVITGVLNI
                     KQAFAGFIDTNVILFVAMFIVGGALFETGMANKVGGVITRFAKTEKQLIFTIMVVVGL
                     MSGVLSNTGTAAVLIPVVIGVAAKSGFSRSRLLMPLVFAAALGGNLSLIGAPGNLIAQ
                     SALQNIGGGFGFFEYAKIGLPMLICGILYFLTIGYRFLPNNATGGEVGSVGEQRDYSH
                     VPQWKQRLSLVVLIATILGMIFEKKIGVSLAVTGCIGALVLVVSGVLTEKQAYKAIDS
                     QTIFIFGGTLALAKALEMTGAGKLVADYVIGMLGQNSSPFMLLIAVFALSVVMTNFMS
                     NTATTALLVPVSLSIAAGMGADPRAVLMATVIGGSCAYATPIGMPANMMVLSAGGYKF
                     VDYAKAGIPLIIVSTIVSLILLPILFPFHP"
     gene            complement(3255..3920)
                     /locus_tag="OPV72_000920"
     CDS             complement(3255..3920)
                     /locus_tag="OPV72_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCR9913288.1"
                     /translation="MQRPKLGKIKLLSAKEQVAAVLRKAILSRELVEGQEITLEGIAG
                     MVGVSSMPVREAFQILAADGLIKVRPNKGAVVLGINEQTIREHYEIRALLESEAVAKA
                     SRPGTDISRIAEVHYAAEKALAENNSAEYSDLNQAFHMEIWNVAGNEKMKMLLCNMWN
                     GLSMGHKVTEEEYAVISIQEHKSILQALELHDETLARQRMREHIIRSMENMLTRYVGD
                     PSA"
     gene            complement(3907..4536)
                     /locus_tag="OPV72_000921"
     CDS             complement(3907..4536)
                     /locus_tag="OPV72_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCR9913289.1"
                     /translation="MKKIQRTQTRDHITQMLRYEILSGNIKAGEELAQESIAEQLGLS
                     RMPVREALQSLEQEGFLIRLPNRHMQVAHLEADRVSHIFRVIAAMAAEMFSLIPSEVG
                     DALLIRAQALAVAEDKSCELECHAMLISYVNNRYLEKVYQQFLDGYVSYVILHLKKDN
                     QESAQLFAELADVIRQGRRDEIGQVMQRYFLSLAEIMRQHMKDWESAEA"
     gene            complement(4656..5594)
                     /gene="mdh"
                     /locus_tag="OPV72_000922"
     CDS             complement(4656..5594)
                     /gene="mdh"
                     /locus_tag="OPV72_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate dehydrogenase"
                     /protein_id="HCR9913290.1"
                     /translation="MKVAVLGAAGGIGQALALLLKNQLPSGSELSLYDIAPVTPGVAV
                     DLSHIPTAVKIKGFSGEDATPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLV
                     QQIAKTCPKACVGIITNPVNTTVAIAAEVLKKAGVYDKNKLFGVTTLDIIRSNTFVAE
                     LKGKLPTEVEVPVIGGHSGVTILPLLSQIPGVSFTEQEAAELTKRIQNAGTEVVEAKA
                     GGGSATLSMGQAAARFGLSLVRALQGEKGVVECAYVEGDGQYARFFSQPLLLGKNGVE
                     ERKSIGTLSTFEQHSLDAMLDTLKKDIQLGEDFINK"
     gene            6008..6478
                     /gene="argR"
                     /locus_tag="OPV72_000923"
     CDS             6008..6478
                     /gene="argR"
                     /locus_tag="OPV72_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001257852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator ArgR"
                     /protein_id="HCR9913291.1"
                     /translation="MRSSAKQEELVRAFKALLKEEKFSSQGEIVLALQDQGFENINQS
                     KVSRMLTKFGAVRTRNAKMEMVYCLPAELGVPTTSSPLKNLVLDIDYNDAVVVIHTSP
                     GAAQLIARLLDSLGKAEGILGTIAGDDTIFTTPASGFSVRDLYEAILELFEQEL"
     gene            6843..7106
                     /gene="yhcN"
                     /locus_tag="OPV72_000924"
     CDS             6843..7106
                     /gene="yhcN"
                     /locus_tag="OPV72_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide/acid stress response protein YhcN"
                     /protein_id="HCR9913292.1"
                     /translation="MKIKTTVATLSILSVLSFGAFAAEPISAEQAQNREAIGSVSVSA
                     IGSSPMDMNAMLSKKADEQGATAYHITEARSGSNWHATAELYK"
     gene            7210..7476
                     /gene="yhcN"
                     /locus_tag="OPV72_000925"
     CDS             7210..7476
                     /gene="yhcN"
                     /locus_tag="OPV72_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide/acid stress response protein YhcN"
                     /protein_id="HCR9913293.1"
                     /translation="MKTKYIIASLGLATLLSFGANAAVHQVNAEQAQNLQPMGTISVS
                     QIGSTPMDMRQEIVAKAEKAGANSYRIIELKEGDNWHATAELYK"
     gene            complement(7536..7808)
                     /locus_tag="OPV72_000926"
     CDS             complement(7536..7808)
                     /locus_tag="OPV72_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913294.1"
                     /translation="MNVYTFDFNDIKNQSDFYREFTQTFGLASEKVSDLDTLWDAVMS
                     DILPLPLEIEFVHLPDKLRRRYGALILLFDEAEEELEGRLRFNVRH"
     gene            complement(7980..9947)
                     /gene="aaeB"
                     /locus_tag="OPV72_000927"
     CDS             complement(7980..9947)
                     /gene="aaeB"
                     /locus_tag="OPV72_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="p-hydroxybenzoic acid efflux pump subunit AaeB"
                     /protein_id="HCR9913295.1"
                     /translation="MGIFSIANQHIRFAVKLACAIVLALFIGFHFQLETPRWAVLTAA
                     IVAAGPAFAAGGEPYSGAIRYRGMLRIIGTFIGCIAALIIIISMIRAPLLMILVCCVW
                     AGFCTWISSLVRIENSYAWGLSGYTALIIVITIQTEPLLTPQFALERCSEIVIGIGCA
                     ILADLLFSPRSIKQEVDRELDCLLVAQYQLMQLCIKHGDSEEVDNAWGDLVRRTAALE
                     GMRSNLNMESSRWVRANRRLKALNTLSLTLITQSCETYLIQNTRPELITDTFRELFET
                     PVETVQDVHRQLKRMRRVIVWTGERETPVTLYSWVGAATRYLLLKRGVISNTKISATE
                     EEILQGEPVVKVESAERHHAMVNFWRTTLSCILGTLFWLWTGWTSGNGAMVMIAVVTS
                     LAMRLPNPRMVCIDFIYGTLAALPLGLLYFLVIIPNTQQSMLLLCLSLAVLGFFIGIE
                     VQKRRLGSMGALASTINIIVLDNPMTFHFIQFLDSALGQIVGCMLAFIVILLVRDKSK
                     DRTGRVLLNQFVSAAVSAMTTNVVRRKENRLPALYQQLFLLMNKFPGDLPKFRLALTM
                     IIAHQRLRDAPIPVNEDLSVFHRQLRRTADHVISAGSDDKRRRYFGQLLDELDIYQEK
                     LRIWEAPPQVTEPVKRLTGMLHKYQNALTDS"
     gene            complement(9953..10885)
                     /gene="aaeA"
                     /locus_tag="OPV72_000928"
     CDS             complement(9953..10885)
                     /gene="aaeA"
                     /locus_tag="OPV72_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="p-hydroxybenzoic acid efflux pump subunit AaeA"
                     /protein_id="HCR9913296.1"
                     /translation="MKTLTRKLSRTAITLVLVILAFIAIFRAWVYYTESPWTRDARFS
                     ADVVAIAPDVAGLITHVNVHDNQLVKKDQVLFTIDQPRYQKALAEAEADVAYYQVLAQ
                     EKRQEAGRRNRLGVQAMSREEIDQANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAP
                     ADGWVTNLNVYAGEFITRGSTAVALVKKNSFYVQAYMEETKLEGVRPGYRAEITPLGS
                     NRVLKGTVDSVAAGVTNASSTSDAKGMATIDSNLEWVRLAQRVPVRIRLDEQQGNLWP
                     AGTTATVVITGKQDRDASQDSFFRKLAHRLREFG"
     gene            complement(10893..11096)
                     /locus_tag="OPV72_000929"
     CDS             complement(10893..11096)
                     /locus_tag="OPV72_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AaeX family protein"
                     /protein_id="HCR9913297.1"
                     /translation="MSLFPVIVVFGLSFPPIFFELLLSLAIFWLVRRMLVPTGIYDFV
                     WHPALFNTALYCCLFYLISRLFV"
     gene            11278..12207
                     /gene="aaeR"
                     /locus_tag="OPV72_000930"
     CDS             11278..12207
                     /gene="aaeR"
                     /locus_tag="OPV72_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator AaeR"
                     /protein_id="HCR9913298.1"
                     /translation="MERLKRMSVFAKVVEFGSFTAAARQLQMSVSSISQTVAKLEDEL
                     QVKLLNRSTRSIGLTEAGKIYYQGCRRMLHEVQDVHEQLYAFNNTPIGTLRIGCSSTM
                     AQNVLAGLTAKLLKEYPGLAVNLVTGIPAPDLIADGLDVVIRVGALQDSSLFSRRLGA
                     MPMVVCAAKPYLAQYGVPEKPADLSSHSWLEYSVRPDNEFELIAPEGISTRLIPQGRF
                     VTNDPMTLVRWLTAGTGIAYVPLMWVIDEINRGDLEILLPRYQSDPRPVYALYTEKDK
                     LPLKVQVVINALTDYFVDVAHLFQGMHGRGKEK"
     gene            complement(12330..13775)
                     /gene="tldD"
                     /locus_tag="OPV72_000931"
     CDS             complement(12330..13775)
                     /gene="tldD"
                     /locus_tag="OPV72_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007888214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloprotease TldD"
                     /protein_id="HCR9913299.1"
                     /translation="MSLNLVSEQLLAANGLNHQDLFAILGQLAERRLDYGDLYFQSSY
                     HESWVLEDRIIKDGSYNIDQGVGVRAISGEKTGFAYADQISLLALEQSAQAARTIVRE
                     NGEGKVKTLAAVAHQPLYTTLDPLQSMSREEKLDILRRVDKAAREADKRVQEVNASLT
                     GVYELILVAATDGTLAADVRPLVRLSVSVQVEEDGKRERGASGGGGRFGYEYFLADLD
                     GEVRADAWAKEAVRMALVNLSAVAAPAGTLPVVLGAGWPGVLLHEAVGHGLEGDFNRR
                     GTSVFSGQIGEQVASALCTVVDDGTMMNRRGSVAIDDEGTPGQYNVLIENGVLKGYMQ
                     DKLNARLMGAAPTGNGRRESYAHLPMPRMTNTYMLAGQSTPQEIIESVEYGIYAPNFG
                     GGQVDITSGKFVFSTSEAYLIENGKVTTPVKGATLIGSGIETMQQISMVGNDLKLDNG
                     VGVCGKEGQSLPVGVGQPTLKVDNLTVGGTA"
     gene            complement(13920..17720)
                     /gene="yhdP"
                     /locus_tag="OPV72_000932"
     CDS             complement(13920..17720)
                     /gene="yhdP"
                     /locus_tag="OPV72_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AsmA2 domain-containing protein YhdP"
                     /protein_id="HCR9913300.1"
                     /translation="MRRLPGILLLTGAALIVIAALLVSGLRLALPHLDAWRPAILNKI
                     ESVTGVPVAASQLSASWQNFGPTLEAHNIHAALKDGGELSIKRVTLALDVWQSLLHMR
                     WQFRDLTFWQLNFRTNTPLQSSDGEGIETSRLSDLFLRQFDHFDLRDSQISFLTLSGQ
                     RAELAIPQLTWLNGKERHRAEGEVSLSSLTGQHGVMQVRMDLRDDDGLLNNGRVWLQA
                     DDIDVKPWLGKWMQDNVALQTARFSLEGWMTLSKGEIAGGDVWLKQGGASWLGDNTTH
                     TLSVDNLTAQISREQPGWQFYIPDTRITLDGKPWPSGALTVAWLPQQDVGGENHTRSD
                     ELRIRASNLELAGLEALRPLAAKLSPVLGEIWQATQPSGKIATLALDIPLQATEKTRF
                     QASWENLAWKQWKLLPGAEHFSGTLAGSVEDGQMKVAMQQAKMPYETVFRAPLEIENG
                     VATLSWLKNENGFQLDGRDIDVKAKAVHARGGFRYLQPTGDEPWLGILAGISTDDGSQ
                     AWRYFPENLMGKALVDYLSGAIQGGEADNATLVYGGNPHLFPYKHNEGQFEVLVPLRN
                     ATFAFQPDWPALKNLNIELDFLNDGLWMRSDSVDLGGVKASKLAAAIPDYSKEKLLID
                     ADINGPGKAVGPYFDETPLKDSLGSTLAELQLDGDVNARLHLDIPLDGEQVTAEGDVS
                     LRNNSLFIKPLNSTLKNLNGKFSFVNGALKSGPLTANWFNQPLNLDFSTTEGAKAYQV
                     AVNLNGNWQPTRMGVLPPQLNDALSGSVTWNGKVGIDLPYHADTTYHIELNGDLRNVS
                     SHLPSPLNKPAGEAIPVNIQADGNLKSFALTGSAGSKNHFNSRWLLNQKLTLDRAIWT
                     TDSRTIPPLPAQQGVELNLPALDGAQWLALFQKGAADNVSSSAEFPQRVTLRTPALSL
                     GGQQWNNLSVVSAPSLNGTKIEAQGREVNATLLMRNHAPWLANIKYLYYNPGVAKTHA
                     SSPTPTSPLASANTISFRGWPDLQLRCEECWLWGQKYGRIDGDFAIKGNTLTLANGLI
                     DTGFARLKANGEWVNAPGNERTSLKGSLHGSNLDTAAGFFGISTPIQNASFNVDYDLH
                     WRNPPWQPEEATLNGILRTRLGKGEFTDLSSGHAGQLLRLLSFDALLRKLRFDFRDTF
                     SEGFYFDSIHSTAWIKDGVLHTDDTLVDGLEADIAMKGSVDLVRRRLDMEAVVAAEIS
                     ATVGVAAAFAVNPIVGAAVFAASKVLGPLWSKVSILRYRITGPVDAPQINEVLRQPRK
                     ESQQ"
     gene            complement(17831..19300)
                     /gene="rng"
                     /locus_tag="OPV72_000933"
     CDS             complement(17831..19300)
                     /gene="rng"
                     /locus_tag="OPV72_000933"
                     /EC_number="3.1.26.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006818051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease G"
                     /protein_id="HCR9913301.1"
                     /translation="MTAELLVNVTPSETRVAYIDGGILQEIHIEREARRGIVGNIYKG
                     RVSRVLPGMQAAFVDIGLDKAAFLHASDIMPHTECVAGDEQKQFTVRDISELVRQGQD
                     LMVQVVKDPLGTKGARLTTDITLPSRYLVFMPGASHVGVSQRIESESERERLKKVVAE
                     YCDEQGGFIIRTAAEGVCEEDLASDAAYLKRVWTKVMERKKRPQTRYQMYGELALAQR
                     VLRDFADAQLDRIRVDSRLTYESLLEFTAEYIPEMTSKLEHYSGHQPIFDLYDVENEI
                     QRALERKVELKSGGYLIIDQTEAMTTVDINTGAFVGHRNLDDTIFNTNIEATQAIARQ
                     LRLRNLGGIIIIDFIDMNNEDHRRRVLHSLEQALSKDRVKTSINGFSPLGLVEMTRKR
                     TRESVEHVLCNECPTCHGRGTVKTVETVCYEIMREIVRVHHAYDSDRFLVYASPAVAE
                     ALKGEESHALAEVEIFVGKQVKVQVEPLYNQEQFDVVMM"
     gene            complement(19290..19883)
                     /gene="maf"
                     /locus_tag="OPV72_000934"
     CDS             complement(19290..19883)
                     /gene="maf"
                     /locus_tag="OPV72_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HCR9913302.1"
                     /translation="MTTLYLASGSPRRQELLIQLGFSFEQVVPGIEEQRRVQESAQQY
                     VVRLAREKAQAGVALVPRDLPVLGADTIVVLNGEVLEKPRDAAHAAEMLRLLSGNTHQ
                     VMTAVALADSQQTLDCLVVTEVTFRTLSAQDITGYVASGEPLDKAGAYGIQGRGGCFV
                     RKINGSYHAVVGLPLVETYELLSHFNALRDKRDKHDG"
     gene            complement(19892..20380)
                     /gene="mreD"
                     /locus_tag="OPV72_000935"
     CDS             complement(19892..20380)
                     /gene="mreD"
                     /locus_tag="OPV72_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001487551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HCR9913303.1"
                     /translation="MASYRSQGRWVIWLSFLIALLLQIMPWPDDIIVFRPNWVLLILL
                     YWILALPHRVNVGTGFVMGAILDLISGSTLGVRALSMSIVAYLVALKFQLFRNLALWQ
                     QALVVMLLSLAVDIIVFWAEFLVINVSFRPEVFWSSVVNGVLWPWLFLLMRKVRQQFA
                     VQ"
     gene            complement(20383..21435)
                     /gene="mreC"
                     /locus_tag="OPV72_000936"
     CDS             complement(20383..21435)
                     /gene="mreC"
                     /locus_tag="OPV72_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HCR9913304.1"
                     /translation="MKPIFSRGPSLQIRLILAVLVALGVIIADSRLGTFSQIRTYMDT
                     AVSPFYFISNGPRELLDSVSQTLASRDQLELENRALRQELLLKNSDLLMLGQYKQENA
                     RLRELLGSPLRQDEQKMVTQVISTVNDPYSDQVVIDKGSVNGVYEGQPVISDKGVVGQ
                     VVAVAKLTSRVLLICDATHALPIQVLRNDIRVIAAGNGCTDDLQLEHLPANTDIRVGD
                     VLVTSGLGGRFPEGYPVAVVSSVKLDTQRAYTVIQARPTAGLQRLRYLLLLWGADRNG
                     ANPMTPEEVHRVANERLMQMMPQVLPSPDAMGPPAPVPDPATGITQPSAGQTTPVSTQ
                     SSPSGATTPSARAPGG"
     gene            complement(21500..22543)
                     /gene="mreB"
                     /locus_tag="OPV72_000937"
     CDS             complement(21500..22543)
                     /gene="mreB"
                     /locus_tag="OPV72_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000913396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreB"
                     /protein_id="HCR9913305.1"
                     /translation="MLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQD
                     RAGSPKSVAAVGHDAKQMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNS
                     FMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATG
                     SMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERI
                     KHEIGSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALE
                     QCPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAEDPLTCVARGGGKALE
                     MIDMHGGDLFSEE"
     gene            complement(22851..24791)
                     /gene="csrD"
                     /locus_tag="OPV72_000938"
     CDS             complement(22851..24791)
                     /gene="csrD"
                     /locus_tag="OPV72_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase E specificity factor CsrD"
                     /protein_id="HCR9913306.1"
                     /translation="MRLTTKFSAFITLLTGLTIFVTLIGCSLSFYNAVQYKYVSRVQA
                     TATAIDTHLVTHDIVSLTPQIDELMIASDIVRVDLLQGERSVYSHSRARGYRPAGTSD
                     MYRELVVPLIKHPGMSLRLVYQDPMGNYFHSLITTAPLTLAIGFIVLILFLSVRWLQR
                     QLSGQELLEIRSTRILNGERGANVRGSVYEWPARTSSALDVLLSEIQFAHEQRSRLDT
                     LIRSYAAQDTKTGLGNRLFFDNQLATLLEDQEKVGVHGVVMMIRLPDFNLLRDSLGGN
                     QAEEQMFMLINLLSTFIMRYPGSLLARYHRSDFAVLLPHRTLKEAESIAGQLLKAVDA
                     LPANKMLDRDDMVHIGICAWRSGQSTDQVMEHAEAAARNAALQGGNSWAIYDDTLPEK
                     GRGNVRWRTLIEQMLNRGGPRLYQKPAVTREGRVHHRELMCRIYDGKEEVSSAEYMPM
                     VLQFGLSEEYDRLQISRLITLLGYWPDENLAMQLTVESLIRPRFQRWLRDTLMQCEKS
                     QRNRIIIELAEADVCQHISRLQPILRLVNALGVRVAVTQAGLTLVSTSWIKALNVELL
                     KLHPSLVRNIEKRTENQLLVQSLVEACAGTPTQVYATGVRSRGEWQTLTKRGVAGGQG
                     DFFASSQLLDTNVKKYSQRYSV"
     gene            24995..25969
                     /locus_tag="OPV72_000939"
     CDS             24995..25969
                     /locus_tag="OPV72_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HCR9913307.1"
                     /translation="MQALILEQQDGKTLASVQHLEESQLPAGDVTVDVHWSSLNYKDA
                     LAITGKGKIIRHFPMIPGIDFAGTVHASEDPRFHAGQEVLLTGWGVGENHWGGLAERA
                     RVKGDWLVALPAGLSSRNAMIIGTAGFTAMLCVMALEDAGIRPQDGEVVVTGASGGVG
                     STAVALLHKLGYQVAAVSGRESTHGYLKSLGANRILSRDEFAESRPLEKQLWAGAIDT
                     VGDKVLAKVLAQMNYGGCVAACGLAGGFALPTTVMPFILRNVRLQGVDSVMTPPARRA
                     EAWARLVKDLPESFYAQAATEITLADAPKFADAIINNQVQGRTLVKIK"
     gene            26082..27086
                     /gene="msrP"
                     /locus_tag="OPV72_000940"
     CDS             26082..27086
                     /gene="msrP"
                     /locus_tag="OPV72_000940"
                     /EC_number="1.8.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-methionine-sulfoxide reductase catalytic
                     subunit MsrP"
                     /protein_id="HCR9913308.1"
                     /translation="MKKIRPLTEADVTAESAFFMQRRQVLKALGISAAALSLPSTAQA
                     DLFSWFKGNDRPKAPAGKPLEFSQPAAWRSDLALTPEDKVTGYNNFYEFGLDKADPAA
                     NAGSLKTEPWTLKISGEVAKPFTLDYDDLTHRFPLEERIYRMRCVEAWSMVVPWIGFP
                     LYKLLAQAQPTSHAKYVAFETLYAPDDMPGQKDRFIGGGLKYPYVEGLRLDEAMHPLT
                     LMTVGVYGKALPPQNGAPIRLIVPWKYGFKGIKSIVSIKLTRERPPTTWNLSAPNEYG
                     FYANVNPHVDHPRWSQATERFIGSGGILDVQRQPTLLFNGYANEVASLYRGLNLRENF
                     "
     gene            27087..27686
                     /gene="msrQ"
                     /locus_tag="OPV72_000941"
     CDS             27087..27686
                     /gene="msrQ"
                     /locus_tag="OPV72_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-methionine-sulfoxide reductase
                     heme-binding subunit MsrQ"
                     /protein_id="HCR9913309.1"
                     /translation="MRLTVKQITWLKVCLHLAGFLPLLWLFWAINHGGLSADPVKDIQ
                     HFTGRTALKFLLATLLVSPLARYAKQPLLIRTRRLLGLWCFVWATLHLTSYALLELGI
                     HNLALLGSELISRPYLTLGIISWLVLLALTLTSTQFAQRKLGKRWQTLHNVVYLVAIL
                     APIHYLWSVKILSPQPVIYAALALALLALRYRKFRQWWR"
     gene            28080..28550
                     /gene="accB"
                     /locus_tag="OPV72_000942"
                     /gene_synonym="fabE"
     CDS             28080..28550
                     /gene="accB"
                     /locus_tag="OPV72_000942"
                     /gene_synonym="fabE"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HCR9913310.1"
                     /translation="MDIRKIKKLIELVEESGISELEISEGEESVRISRTTANAGFPVM
                     QQAYAAPMMQQPALSNAVAPAATPAMEAPAAAEISGHIVRSPMVGTFYRTPSPDAKAF
                     IEVGQKVNVGDTLCIVEAMKMMNQIEADKAGTVKAILVESGQPVEFDEPLVVIE"
     gene            28561..29910
                     /gene="accC"
                     /locus_tag="OPV72_000943"
     CDS             28561..29910
                     /gene="accC"
                     /locus_tag="OPV72_000943"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009483995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HCR9913311.1"
                     /translation="MLDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLL
                     ADETVCIGPAPSVKSYLNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIF
                     IGPKADTIRLMGDKVSAITAMKKAGVPTVPGSDGPLGDDMNANRAHAKRIGYPVIIKA
                     SGGGGGRGMRVVRSDAELAQSISMTKAEAKAAFSNDMVYMEKYLENPRHIEIQVLADG
                     QGNAIYLAERDCSMQRRHQKVVEEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFE
                     FLFENGEFYFIEMNTRIQVEHPVTEMITGVDLIKEQLRIAAGQPLSITQDEVVVRGHA
                     VECRINAEDPNTFLPSPGKITRFHAPGGFGVRWESHIYAGYTVPPYYDSMIGKLICYG
                     ENRDVAIARMKNALQELIIDGIKTNIDLQTRIMNDEHFQHGGTNIHYLEKKLGLQEK"
     gene            30019..30261
                     /locus_tag="OPV72_000944"
     CDS             30019..30261
                     /locus_tag="OPV72_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhdT family protein"
                     /protein_id="HCR9913312.1"
                     /translation="MDARFVQAHKEARWALWLTLCYLAAWLVAAYLSGDSPGITGLPH
                     WFEMACLLTPLVFILLCWAMVKFIYRDIPLEDDDAA"
     gene            30251..31702
                     /gene="panF"
                     /locus_tag="OPV72_000945"
     CDS             30251..31702
                     /gene="panF"
                     /locus_tag="OPV72_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/pantothenate symporter"
                     /protein_id="HCR9913313.1"
                     /translation="MQLEVILPLVAYLVVVFGVSIYAMRKRTAGTFLNEYFLGSRSMG
                     GIVLAMTLTATYISASSFIGGPGAAYKYGLGWVLLAMIQLPAVWLSLGILGKKFAILA
                     RRYNAVTLNDMLFARYQSRLLVWLASLSLLVAFIGAMTVQFIGGARLLETAAGIPYET
                     GLLIFGVSIALYTAFGGFRASVLNDTLQGLVMLVGTIVLLVGVVHAAGGLHQAVDTLH
                     ALDPKLVTPQGADDILSPAFMTSFWVLVCFGVIGLPHTAVRCISYKDSKAVHRGIIIG
                     TIVVAILMFGMHLAGALGRAVLPDLTVPDLVIPTLMVKVLPPFAAGIFLAAPMAAIMS
                     TINAQLLQSSATIIKDLYLNLRPDQMQNEIRLKRMSAAITLLLGALLLLAAWKPPEMI
                     IWLNLLAFGGLEAVFLWPLVLGLYWERANAAGALSAMIVGGVLYALLATFNIQYLGFH
                     PIVPALLLSLLAFLIGNRFGSSASQATVLSTDK"
     gene            31714..32595
                     /gene="prmA"
                     /locus_tag="OPV72_000946"
     CDS             31714..32595
                     /gene="prmA"
                     /locus_tag="OPV72_000946"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HCR9913314.1"
                     /translation="MPWIQLKLNTTGANAEELSDALMEAGAVSITFQDTHDTPVFEPL
                     PGETRLWGDTDVIGLFDAETDMKDVVAILEQHPLLGAGFAHKIEQLEDKDWEREWMDN
                     FHPMRFGERLWICPSWRDIPDENAVNVMLDPGLAFGTGTHPTTSLCLQWLDGLDLNGK
                     TVIDFGCGSGILAIAALKLGAAKAIGIDIDPQAIQASRDNAERNGVSDRLELYLPKDQ
                     PEAMKADVVVANILAGPLRELAPLISVLPVEGGLLGLSGILASQAESVCDAYAELFTL
                     DPVVEKEEWCRITGRKK"
BASE COUNT         7955 a         9131 c         8320 g         7674 t
ORIGIN      
        1 gccagcacga atcccatgcc gaggagcatc agagtgaagc cttcacctaa tagcagagct
       61 gcattagtca taaaatagcc ttcaggcagg aggcacgata atggggctat ttatgacgat
      121 gaaataataa gggtggattt ccctgagccg ccccggccag agcccttggt tattattatc
      181 gtcataacgt attaccacca ttatcgtgca atttacgtaa tcaggtttat ttgatgaaac
      241 ttacgttctg gcatatttca tcagcgacga tctctttacg ctgattaaaa ataattttgt
      301 tctgttcaaa cagattattc ccatgggtat caatagaaac aatcagcggg ccaaactctt
      361 taacccgaca gacccacagc gtttccggca tccccagatc gcgccattgg gcatcttcaa
      421 tttcttccac gcacacggcg gctacaaccg cacaaccggc agggaatacg cagtgcagcg
      481 ctttgtgttc agcacagccc tcttcggtac ctttacccat accgccttta cctacaatta
      541 atttcacgcc agtctgcgca ataaactctt tttcgaattt ctccatacgc atgctggtgg
      601 ttgggccaac ggagaccatt tcaaacttat cgtcttcgcc tttaattggg cggacaatgg
      661 ggccagcgtg taaaatagcg ccgccgcgaa catctaccgg aagttcgcga ccaccttcaa
      721 ttaaacggcg atgggctacg tcacggcagg taacaatatg accgttgaga taaataatat
      781 cgccagcctt aatatccgct aaatcttcat ctttaattgg cgtagtcagg atttttttag
      841 tcatcagaaa ttcactccgc tgtgagacgt aatggtgtaa ttcaaatctt tatcgaaaac
      901 gatgtgccct ttacggtgcg accagcagcc gacgtttacc gccacgccga tggtagaagg
      961 atgacgtgcg gtgttttcaa tgttcacgcc cataacggag gtattaccgg acatcccctg
     1021 cggccccagg ccaattttgt taatgccgtc ttccagcatt ttttccagcg aggctgcacg
     1081 ctcattctcg ttatgcgaac cgatcggacg catcagcgct tttttcgata gcagtgccgc
     1141 cgtttcaaca gaggtcgcta cgcccacgcc aaccagcagc ggcggacaag cgttgaggcc
     1201 gtagctggtc atcacatcca gtacaaagcg ggtcacacct tcatagcctg cacccggcat
     1261 cagcaccatc gctttccccg gcagagaaca accaccgccc gccatatagg tataaatgct
     1321 gcactgatcg gaattgggaa cgatttccca gaagaccgtc ggcgtacctt tacccacgtt
     1381 tttaccggtg ttgtattcat caaaagtttc tacgctgttg tggcgcagcg gagaatctac
     1441 agttgctttg atcaccgcct cacgcaacaa cgcttccagc tcgccaatca gcggaaagtt
     1501 cgtcccgcac tccaccaaaa actgaatgac accggtgtcc tggcaggaag gtcgatccag
     1561 ctctttcgcc agacgctggt tctcaatcat ggtagtaaag atgacgtcgg ccagtttact
     1621 ggtctctttc ttatgcaaat cttccagttt tgcagtgaca tcatcaggca aaactttgcc
     1681 ggtatatccc acaaacttgg ccataacgtc ggtcatatgg gatatctgtt cacttttgct
     1741 cataaatgct ccttagtcag aacagcttcc gttaattacg gatgaaaagg gaaaaggatt
     1801 ggcagcagga tcaagctgac aatggttgaa acgataatca gggggatacc ggccttagcg
     1861 tagtcgacaa atttatagcc acccgcggag agcaccatca tgttggcagg cataccgata
     1921 ggagttgcgt aggcgcagga accgccaatg accgtcgcca tcagaaccgc acgcgggtcg
     1981 gcccccatac ctgcggcaat ggacaaactc accggcacca atagcgctgt cgttgcggta
     2041 ttggacataa agttggtcat cacaacggat aaggcgaaaa cggcgatcag caacatgaac
     2101 ggtgaggagt tttgccccag catgccgatt acatagtccg caaccagctt gcctgccccg
     2161 gtcatttcca gcgcttttgc cagcgccagg gtgccgccaa agataaaaat agtctgtgaa
     2221 tcaatggctt tataggcctg tttttccgtg agtacgccgc ttacgaccag cacaagagcg
     2281 ccaatacaac cggtcacggc caggctgaca ccgatcttct tctcaaagat catgccgagg
     2341 atcgttgcga tcaacaccac gagtgagagc cgttgtttcc actgtggaac atggctgtag
     2401 tcacgttgct ccccgacgct ccccacctca ccgccggtcg cattattcgg cagaaagcga
     2461 tagccaatag tcaggaagta gagaatgccg cagatgagca tcgggagacc gatttttgcg
     2521 tattcaaaaa agccaaagcc gccgccaata ttctgtagcg cagactgcgc gataagattt
     2581 cccggcgcgc caattaacga caggttaccg cccaacgcag cggcgaaaac cagcggcatc
     2641 agtagacgag aacgcgagaa gcccgatttt gccgccacgc cgatcaccac cggaatcaaa
     2701 accgcagcgg taccggtgtt agagaggacg ccagacatca aacccaccac caccataatg
     2761 gtgaagatca gctgtttttc tgttttcgcg aagcgcgtga tgacgccgcc cactttgttt
     2821 gccataccgg tctcaaacaa cgcaccgccc acgataaaca tcgcgacaaa gaggatgacg
     2881 ttagtgtcga taaagccagc aaaggcctgt ttaatattca gaacgccggt gataactaag
     2941 gccacgcaga caatcatgga agtgacggcc agcggcactt tttcccatac aaacatgacg
     3001 atagcgaaca ccaataaaca tagggtaagg gtaatgggtt ccatatttat aattatccaa
     3061 tcaatgatat atgatattgt atccaatatt gacgaggaga aattattccc atacaaaaaa
     3121 taagtcaaat cgtttctcag gaaagatgca ggagtgggat ctacatcaag atcgtagttg
     3181 gatcgttact ggacgtgatt aatagaattg aagaattggt tgaagcgcct gcgatactca
     3241 cgcaggcgaa aagatcaggc agaagggtca ccaacatagc gggtcagcat attctccatt
     3301 gagcgaataa tgtgttcgcg catgcgctgg cgtgccaatg tttcatcatg aagttcaaga
     3361 gcttgcagaa tacttttatg ttcctgaatg gaaatcacgg catactcttc ttcggtgacc
     3421 ttatggccca tcgacaggcc gttccacata ttacagagca acattttcat tttttcgttg
     3481 ccagcaacat tccatatttc catatgaaat gcctgattca ggtcggagta ttccgccgag
     3541 ttattttccg cgagagcctt ttcagcggca taatgcacct cggctatccg cgaaatatcg
     3601 gtgccaggac gagaagcttt agccaccgcc tcactttcta acagcgcgcg aatttcatag
     3661 tgttcacgga tcgtttgttc attgatgccc aacaccaccg cccctttatt agggcgcact
     3721 tttatcagcc catccgccgc cagaatctga aacgcctcgc gcactggcat actggacacg
     3781 ccgaccattc cggcaatgcc ttctaacgta atctcttgcc cttccactaa ctccctcgaa
     3841 agaatcgctt tacgcagcac cgccgcgacc tgttctttcg ctgaaagaag cttaatcttc
     3901 cctaacttag gcctctgcac tttcccaatc cttcatatgt tgacgcatta tttctgctaa
     3961 agagaggaaa taacgctgca taacttgccc aatctcatca cgccgcccct ggcgtatgac
     4021 gtcagccagt tcagcgaaaa gctgcgccga ctcctgatta tcttttttca gatgcaaaat
     4081 aacataagag acataaccgt ccaggaactg ctgatacacc ttttccagat agcggttatt
     4141 cacataagaa atcagcatcg catgacactc cagttcgcag gatttgtctt ctgcgacagc
     4201 cagcgcttgc gcacgtatca ggagggcatc gcctacttcg ctgggtatca gcgaaaacat
     4261 ttcggcggcc atcgcggcaa tcacgcgaaa aatatgactc acgcgatcgg cctcaagatg
     4321 cgcgacctgc atgtgcctgt tgggcagtcg gattaaaaaa ccttcctgtt cgagtgactg
     4381 tagcgcttct cgaaccggca ttcgtgaaag accgagctgc tccgcaatac tttcctgcgc
     4441 gagttcttct cccgctttta tattgccgga aagaatttca tagcgaagca tttgcgtaat
     4501 gtgatcgcgg gtttgcgttc tttggatctt tttcacgacg ttctcgttaa taaccgataa
     4561 gacgtgagga gtttagcaga tttagtgctt gatttcgtgg cttgtttata gttaaagaag
     4621 ccggagcaaa agccccggca tcgggcagga acagcttatt tattaataaa atcttcaccc
     4681 aactgaatat cttttttcag cgtatccagc atagcgtcca gcgaatgttg ctcgaaagtg
     4741 ctcagtgtgc cgatggattt acgctcttct acgccgtttt tacccagcag cagcggctga
     4801 gagaagaaac gggcatactg accgtcgcct tccacatagg cgcattccac cacgcctttt
     4861 tcgccctgca gagcgcgaac cagagaaaga ccgaaacgcg cggcagcctg gcccatagag
     4921 agggttgccg atccgccgcc ggctttcgcc tcgacgactt cagtaccggc gttctgaata
     4981 cgtttagtca gctcggccgc ttcttgttcg gtaaaactta cgcctggaat ctgcgatagc
     5041 agcggcagaa tcgtcacgcc ggagtgcccg ccaatcaccg gaacttcaac ttccgttggc
     5101 agcttacctt tcagctctgc gacaaaggta ttagagcgga tgatatccag cgtggtaacg
     5161 ccaaacagtt tgtttttgtc gtatacgcct gcttttttca acacttccgc cgcaatcgca
     5221 acggtggtgt tcaccgggtt ggtgataatg cccacgcacg ctttcgggca ggttttagcg
     5281 atctgctgca ccaggttttt cacgatgccg gcgttaacgt taaacaggtc ggaacggtcc
     5341 atacccggct tacgcgccac acccgcagaa atcagtacta cgtcagcgcc ttcaagcgcc
     5401 ggggttgcgt cttcaccgga gaaacctttg atttttacag cggtggggat gtggcttaaa
     5461 tcaacggcca caccgggagt cactggagcg atgtcgtaca gggagagttc tgaacctgaa
     5521 ggcagttggt tttttaaaag taatgccagc gcctgaccga taccaccagc agcgccgagg
     5581 actgcgactt tcatcctaaa ctccttatta tatgattagc taagtgtcta ttgctccgcg
     5641 gcggcgacct taattcacaa attcaatgat tacaatcctc actcatcaag aatgcggagt
     5701 cgcgcaattt tggcttttat gcatttaatt tgcgtaatcc ggatcggctg caaccagaga
     5761 gcaacgttct acaggtggtg acaatatacc ctactaccct ctcaaaacaa catcattttg
     5821 ataacaatta atttactttt aatcttattt gcgaggcgtg acacaggcat gtttcttgat
     5881 tacgaaattt gataaaattc cgctctttca taacattatt tcagccttaa acaaggcaga
     5941 ctgtttgcat aaaaattcat ctgtatgcac aataatgttg tttctaccgc catattacgg
     6001 gtgacttatg cgaagctcgg ctaaacaaga agaactagta agagcgttta aagcgctcct
     6061 caaagaagaa aaattcagct cacagggcga aatcgtcctc gcgttgcagg atcagggctt
     6121 tgaaaatatc aatcagtcca aggtctcgcg catgttgact aagttcggcg cagtgcgtac
     6181 acgtaacgca aaaatggaaa tggtgtactg tcttccggct gaactgggcg tcccaacaac
     6241 atccagtccg ttgaaaaatc tggtgctgga tatcgactat aacgatgctg tcgtggtgat
     6301 tcataccagc cccggcgcgg cacaactcat tgcgcgcctg ctggattcac tggggaaagc
     6361 agaaggtatt ctcggcacga ttgccggcga cgatactatc ttcactacgc ctgccagcgg
     6421 cttttccgta agagatctgt acgaagccat tctggaactt tttgaacaag agctttagtc
     6481 ccacttcctc cgtcgtcgta cggcggaggc atctttttgc cctctcccct cgccgctttc
     6541 ctgtacggct atcatttggc aaatcatgcc cttaaacatt caccacatga atgaaaaatc
     6601 aaaaaaacgc acaaaatgtc aattttttta accagttgat tttcttttat ttttcaaacg
     6661 acagcggcga aaaacagcaa ttttaattcc ataacgttat aaaaaataaa atttttaatg
     6721 tctttaaaaa gcagaaacaa ttagcgtggt attaattaat tgcgtgatta gtgtatactt
     6781 aattttgtga tgagggtcac gaaacaaaga ccccagtaaa ggaattcgac gaggtaaaaa
     6841 tcatgaaaat caaaaccact gttgcaacat taagcattct gtccgttctc tcttttggcg
     6901 ctttcgccgc agaacctatc agcgcagagc aagcgcaaaa ccgtgaagca atcggatcgg
     6961 tttcagtcag cgctatcggc tcatcgccta tggatatgaa tgccatgctg agcaaaaaag
     7021 cagatgaaca aggcgctacg gcctaccaca ttaccgaagc gcgtagcggc agcaactggc
     7081 acgccactgc cgaactgtac aaataaaatt cacctgccat cgcatataac gtgtcgttac
     7141 ttcgcggaga tatcgcataa gaaaagccca ttaatccgcg aggttgaccc tataaaggaa
     7201 taaaagacca tgaaaacgaa atacattatc gcatcactcg gcctggccac tctgctctct
     7261 ttcggcgcaa atgccgcagt acaccaggtt aacgcggaac aggcgcagaa tctgcaaccg
     7321 atgggcacca tttccgtctc gcagattggc agtacgccaa tggatatgcg ccaggagatc
     7381 gtcgctaaag ccgaaaaagc aggcgctaat agctatcgca tcatcgaatt aaaagaaggt
     7441 gataactggc acgccaccgc cgagttgtat aagtaaacct tcgtcgtcta acccgacgac
     7501 ttgcccccgc atgccggggg cttttttatg ctttttcaat gccggacatt aaaccgtagc
     7561 cgtccctcca gctcttcttc cgcttcatca aagagtaaaa tcagcgcccc gtagcgcctg
     7621 cgcagtttat caggcaggtg aacgaactca atctctagcg gtaggggtaa gatatcgctc
     7681 attaccgcat cccataatgt atcaagatcg cttactttct cactggcaag gccaaacgtc
     7741 tgcgtaaact cgcgataaaa atcgctttgg tttttaatat cattaaaatc aaatgtatag
     7801 acattcatag ccagccacca tccccgacag acaattgtct gttttactac taagcatcat
     7861 tatgcagagg tttcacttcc agaaacgctt ttagccccgg agcactcttg cgctgttttt
     7921 gtatctcaaa taagtatagt cataaaaaaa ccgacgcttt tggcatcggt tcttgtggat
     7981 tagctatcgg taagcgcgtt ctggtattta tgtaacatgc ccgtcaggcg tttaaccggt
     8041 tccgtcacct gcggcggcgc ctcccagata cgtaatttct cctgatagat atccagctca
     8101 tccagcaact gaccaaagta gcgtcgccgt ttatcatcgc ttccggcgga aataacatgg
     8161 tctgcggtac gacgaagctg gcggtggaac actgacagat cttcattaac cggtatcggc
     8221 gcgtcgcgca gacgttgatg agcaatgatc atcgttagcg ccaggcggaa cttcggcaaa
     8281 tcgcctggga atttattcat cagcaaaaag agttgctgat ataacgcagg cagacggttt
     8341 tctttacggc gtaccacgtt ggtcgtcatt gccgagaccg cagcggaaac aaactgatta
     8401 agcagcacgc gaccggttcg atctttggat ttatcacgca ccagcaggat gacgataaac
     8461 gccagcatac agccgacaat ttgccccaac gcgctgtcga ggaactggat gaaatggaac
     8521 gtcatcggat tatccaacac aataatgtta atcgtactgg ccagcgcccc catcgacccc
     8581 agacgccgtt tctgaacttc aataccgata aagaacccca ataccgccag gctcaaacat
     8641 aacaacagca tactttgctg cgtattggga ataatcacca ggaaatagag caatcccagc
     8701 ggcaacgccg ccagagtgcc ataaataaaa tcaatgcaga ccatgcgcgg attgggtaaa
     8761 cgcatcgcca gcgaggtcac cacggcaatc atcaccatcg cgccattacc cgatgtccag
     8821 ccggtccata gccagaataa tgtccccaga atgcaggaaa gcgtggtgcg ccagaagttc
     8881 accatcgcat ggtggcgttc agcggattcc actttaacta cgggctcgcc ttgcaggatc
     8941 tcttcttccg tcgcgctgat tttggtgtta ctgatcacgc cgcgtttaag caacagatag
     9001 cgcgttgcag cgcctaccca gctataaagc gtgacgggcg tttcgcgctc gccggtccaa
     9061 acaatgacac gccgcatccg ttttaactgc ctgtggacgt cctgtaccgt ttcaaccggc
     9121 gtctcgaaca gttcccggaa tgtatcggta atcagttccg gccgcgtgtt ttgaataaga
     9181 taagtttcac aggattgcgt aatcagcgtg agcgaaagcg tattcaacgc tttcaggcgg
     9241 cggttagcgc gtacccagcg cgaagattcc atattcagat tacttcgcat cccctccagc
     9301 gccgccgtgc gtcgcaccag atcgccccag gcgttgtcga cttcttcgct gtcgccatgc
     9361 ttaatacaaa gttgcattag ctgatattgc gctaccagta aacagtccag ttcgcgatca
     9421 acctcctgct ttatcgatcg cggcgagaaa agcagatccg ctaaaatagc gcagccaatg
     9481 ccgatgacga tttcgctaca gcgctcaagc gcaaattgcg gcgtaagcag cggctccgtc
     9541 tgaatggtaa tcacaatgat cagcgcagta taacctgaca gtccccacgc ataagagttt
     9601 tcgatccgta ctaaagagga gatccaggta caaaaaccgg cccagacaca gcacaccaga
     9661 atcatcaata gcggcgcgcg gatcatagag ataataatga taagcgcggc gatacagcca
     9721 ataaacgtcc cgataatacg caacattccg cgataacgga tagcgccgga atagggttcc
     9781 ccgccggcgg caaatgccgg gcctgccgcc acgatcgcgg cggtcagcac cgcccaacgc
     9841 ggcgtctcca gctgaaaatg gaagccgata aataatgcca gcacaatggc gcacgccagc
     9901 tttaccgcaa aacgaatgtg ctggttggca atggagaaaa tgcccatgac gattaaccga
     9961 attcgcgcag ccggtgcgcc agtttacgga agaaggagtc ctggcttgcg tcacgatcct
    10021 gcttaccggt gatcacgacg gttgccgtcg taccggcagg ccacaaattc ccctgctgct
    10081 cgtcgagccg gatgcgcacc gggacacgct gggccagacg cacccattcg aggttagagt
    10141 ctatcgtcgc catccctttc gcatcgctgg tactgctggc attcgttacc cctgccgcca
    10201 cgctatcgac ggtgcctttt aatacccggt tgctgccgag cggcgtgatt tcggcacgat
    10261 atcccggacg cacgccttcc agcttggtct cttccatata ggcctgcacg taaaaagagt
    10321 tctttttcac cagggcgacg gctgtggaac cgcgggtaat aaattcaccg gcataaacat
    10381 tgaggttagt tacccagccg tctgcaggcg cacgaatgac ggtacgctcc agatcgagtt
    10441 tagccagatc gcgcgtcgcc tgggctttag ccaattgatg cagtaccgtc tgcaagacgt
    10501 tgttcgcctg atcgatctct tcccgggaca tcgcctgtac gccgaggcga ttacggcgac
    10561 cggcttcctg gcgtttttcc tgcgccagta cctgataata ggctacatca gcttccgctt
    10621 ccgccagcgc tttttgatag cgtggctgat cgatggtaaa caggacctga tcctttttca
    10681 ccagttggtt atcatgcacg tttacatggg taatcaggcc cgcgacatcc ggggcaatag
    10741 cgacgacatc ggcgctaaaa cgcgcgtcgc gcgtccaggg tgattcggtg taatacaccc
    10801 aggcgcggaa aatggcgata aaggccagaa taaccagtac gagggtaatg gccgtacggg
    10861 agagttttct tgttagtgtt ttcacttcaa cctcaaacga acaggcgcga tattaaataa
    10921 aacagacaac aatacagcgc ggtattgaac agagccggat gccagacaaa atcatagatg
    10981 cccgtcggca caagcatccg acgcaccagc caaaaaatag ccagtgacaa aagcaattcg
    11041 aaaaatatcg gtgggaagga aagaccaaac accacgataa cgggaaacag actcatgttg
    11101 accttgattt ctgagagaga gcaggcgata gattgttaag ctacatcgcc gcagagaagg
    11161 gcaagagacg ccaggcgaga gcgacatagc tcttattcga ataatagtat attaacgtaa
    11221 ttgttatgct gttatctata ttatgtgatc taaatcactt ttaagccaga gtgaataatg
    11281 gaacgattaa aacgaatgtc ggtattcgcc aaagttgttg agtttggctc ttttaccgcc
    11341 gcagccagac agctgcaaat gagcgtatcg tccatcagcc agactgtggc gaaactggaa
    11401 gatgagcttc aggttaaatt gctcaaccgc agcacacgca gcattgggct caccgaagct
    11461 ggaaaaatct attatcaggg ctgtcgtcgt atgctgcatg aagtgcagga tgttcacgag
    11521 cagctttacg cttttaataa cacgcctatc ggtacattgc gtatcggctg ttcttcaacc
    11581 atggcgcaaa atgtgctggc cgggcttacc gcaaaattat taaaagagta tcccggtctg
    11641 gcggtcaatc tggtgacagg aattccggcc ccggatttaa ttgccgacgg gctggacgtg
    11701 gtgatccgcg tgggcgcgct gcaagactcc agcctgtttt cccgtcgact cggcgcgatg
    11761 ccgatggttg tgtgcgccgc caagccctac ctcgctcagt acggcgtccc ggaaaaaccc
    11821 gccgatctca gtagccattc ctggctggaa tatagcgtgc gcccggataa tgagtttgaa
    11881 cttattgcgc cggaaggaat ttctacccga ctgattccac aggggcggtt cgtcactaac
    11941 gatccgatga cgctggtacg ctggctgacc gccggaaccg gaatcgccta tgtgccgctg
    12001 atgtgggtga tcgatgagat caatcgtggc gatctggaga tcctgctgcc tcgctatcag
    12061 tccgatcccc gtccggtgta cgcgctgtac accgaaaaag ataagctgcc gcttaaagtg
    12121 caggtagtga ttaacgcgtt aactgactat tttgtcgatg tcgcacacct gtttcagggg
    12181 atgcacgggc gagggaaaga aaaataaaaa caccgggtaa ttgctgaaga cgattgtaga
    12241 tcagatgcca cccgaggcag acattgcctg atggcgctgc gcttatcagg cctgggcggc
    12301 acataccaca ggcctgataa ggcggacagt tatgcggtgc cgccaaccgt caggttatcg
    12361 actttcagcg tcggctggcc tacgcctacc ggcaggcttt ggccctcttt accgcagacc
    12421 cccaccccgt tatccagctt aaggtcgttg ccgaccatgg agatctgttg catcgtttca
    12481 atgcctgatc caatcaacgt cgcgcccttc accggcgtcg tgactttgcc gttttcaatc
    12541 agatacgctt ccgaggtaga gaacacaaac ttgccggagg tgatatccac ctgaccgccg
    12601 ccaaagttag gcgcatagat gccatactca acggattcga taatttcctg cggcgttgac
    12661 tgccccgcca acatataagt attcgtcata cgcggcatcg gcagatgcgc ataagattcg
    12721 cgacgcccgt taccggtcgg cgcagcgccc atcaggcgcg cgttcagctt gtcctgcatg
    12781 tatcctttca gcacgccatt ttcaatcaat acgttgtact ggcctggcgt accttcatca
    12841 tcgatagcaa cggagccacg acggttcatc attgtgccgt catccactac ggtgcaaagc
    12901 gcggaggcaa cctgctcacc gatctgaccg ctaaacacag acgtcccacg acggttgaaa
    12961 tcaccttcca gcccgtgccc gaccgcttcg tgcagcaata cgcccggcca cccggcgccc
    13021 agaaccaccg gtaacgtccc cgctggcgca gcgaccgcgg agagattaac cagcgccatg
    13081 cgtaccgctt ctttcgccca cgcgtcggcg cgcacctcgc cgtcaagatc ggcaagaaaa
    13141 tactcataac caaagcgacc gccgccgccg ctggcgccgc gctcgcgttt accgtcttct
    13201 tccacctgca cgctaacgga caaacgcacc agtggacgga catccgccgc cagcgtcccg
    13261 tcggtcgccg ccacgaggat taattcatat acgccggtca ggctggcgtt aacttcctgc
    13321 acgcgtttat cggcttctcg cgccgcttta tcaacgcgtc tgaggatatc cagcttctct
    13381 tcgcggctca tactttgcag cggatcaagg gtggtgtaga gcggctgatg cgctacggcg
    13441 gcgagcgttt ttaccttgcc ttcgccgttc tcgcgtacaa tggttcgcgc tgcctgcgca
    13501 ctctgctcca gcgcaaggag gcttatctgg tcagcataag caaaaccggt tttttcgccg
    13561 ctaatggcgc gaacgccaac gccctggtcg atattatatg aaccatcttt aatgatgcgg
    13621 tcttctaaaa cccaggattc gtgatagctc gactgaaaat agaggtcgcc ataatcaaga
    13681 cggcgttcgg ccagttggcc caaaatagcg aacagatcct gatggttcag gccattcgcc
    13741 gctagcaatt gttcacttac caggttcaga ctcatcgttt ttgctactcg ttgatttctg
    13801 ccggatggcg gttcacgcct tatccggact acgttgttag attgtgcaaa ccggataaac
    13861 gcagcgccgt ccggcatgac tatttactga gagtggggca attcctcgcc cccgtcaaat
    13921 cattgctggc tttcttttct cggttggcgc agaacttcgt tgatctgcgg cgcatcgacc
    13981 ggaccggtaa tgcgataacg cagaatggag accttgctcc atagcggccc caacacttta
    14041 ctggcggcaa ataccgccgc gccgacaatc gggttaacgg caaacgcggc agcgacgccc
    14101 acggtggcgg aaatttccgc cgcgacaacg gcctccatat caagacgacg acgcaccaga
    14161 tcaacagaac ctttcattgc aatatccgct tccagcccat ccaccagcgt atcgtcagta
    14221 tgcaggacgc catctttaat ccacgcggta ctatgaatag agtcgaaata gaagccctcg
    14281 ctaaaggtat ctctgaagtc aaaccgcagc ttacgcagca acgcatcaaa actgagcagc
    14341 cgcagtagct gtccggcatg accgctactg agatcagtaa actcgccttt gcccagacgc
    14401 gtacgtaaaa tcccgttgag cgtggcttcc tcaggttgcc agggcgggtt tcgccagtgc
    14461 agatcgtaat ctacgttaaa agacgcgttc tggattggcg tcgagatgcc gaagaacccg
    14521 gcagccgtgt cgaggttact accatgcaga ctacctttca gcgaggttcg ttcattaccc
    14581 ggcgcattca cccactcgcc gttcgctttc aaacgggcga atccggtatc gatcaggcca
    14641 ttcgccagag tcagcgtatt gcctttgatg gcgaaatcgc catcaatacg cccatatttt
    14701 tgcccccata gccagcactc ttcgcagcga agctgtaagt ccggccagcc gcggaagcta
    14761 atcgtgttcg ccgaagccaa cggcgatgtc ggcgttggtg acgaggcgtg cgtttttgcg
    14821 acgccagggt tgtagtacag gtacttaatg ttcgccagcc acggcgcatg gttgcgcatg
    14881 agtagcgtgg cgttcacctc acggccctgc gcttcaattt ttgttccgtt cagcgagggg
    14941 gctgaaacga cgctcaaatt gttccactgc tggccgccca gcgatagcgc gggagtacgc
    15001 aacgtgacgc gttgaggaaa ctcggccgaa ctgctcacgt tatccgccgc gcctttctgg
    15061 aataacgcca gccattgcgc gccatccagc gccggcagat tgagctcaac gccttgttga
    15121 gcaggtaatg gcggaatcgt ccggctgtcc gtcgtccaga tagcccgatc caacgtcagc
    15181 ttctgattta ataaccagcg gctgttaaag tgatttttac tccctgcgct ccccgttagc
    15241 gcaaaacttt tcaggttgcc gtcagcctga atgttcaccg gaatggcttc gcctgcgggt
    15301 ttatttagcg gagaaggtaa gtgactgctc acatttctca gatcgccgtt cagctcgatg
    15361 tgataagtgg tgtcagcgtg atatggaaga tcgatgccga ctttaccatt ccacgtcacg
    15421 ctgccgctca gggcgtcatt cagttgcggc ggtaagacgc ccatacgcgt tggctgccag
    15481 ttaccgttca ggttgacggc gacctgatag gcttttgccc cttccgtcgt actgaaatcc
    15541 aggttaagcg gctgattaaa ccagtttgcc gtcagtggcc cgctttttag cgcgccattc
    15601 acaaagctga atttaccgtt cagatttttg agcgtgctgt ttagcggctt aataaacaga
    15661 ctgttattac gcaacgagac atcgccctcg gcggtaacct gttctccgtc cagcggaata
    15721 tcaagatgta agcgagcatt cacatcgcca tctaattgga gctccgccag cgtcgagcca
    15781 agcgagtctt ttagcggcgt ctcgtcaaaa taaggcccaa cggcttttcc cggcccgtta
    15841 atatcggcat caatgagcag tttctctttg gaataatccg gaatcgccgc cgcgagtttg
    15901 ctggccttca ccccgcccaa atcgacgcta tccgaacgca tccacaggcc gtcgttcagg
    15961 aaatccagtt caatgttgag attttttagc gccggccagt cgggttgaaa agcaaacgtc
    16021 gcattgcgta gcggcaccag cacttcaaac tgaccttcgt tatgcttata gggaaagagg
    16081 tgcgggttac caccgtaaac caacgtggcg ttatccgcct cgccgccctg aatcgcgccg
    16141 ctaaggtaat cgactagcgc tttgcccatc aggttttccg gaaaatagcg ccacgcctga
    16201 gatccatcat cggtactgat tccggccaga atacccagcc acggttcgtc gcccgtcggt
    16261 tgcagatagc ggaacccgcc gcgcgcatgt accgcctttg ctttgacgtc aatgtcgcgg
    16321 ccatcaagct gaaagccgtt ctcattcttc aaccagctaa gcgtcgcgac gccgttttca
    16381 atttccagcg gcgcgcgaaa aacggtttca tagggcatct tagcctgctg catcgcaacc
    16441 ttcatctgcc cgtcttctac gcttcccgcc agcgtaccgg aaaaatgttc cgcgccgggc
    16501 aacagcttcc actgtttcca ggcaagattt tcccacgatg cctgaaaacg cgttttttcg
    16561 gtcgcctgta gcggaatatc cagcgccagt gtggcgatct ttccgctcgg ctgcgtagcc
    16621 tgccatattt cgcccagcac aggcgacagt ttagccgcca gcggacgtaa tgcttccagc
    16681 cccgccagtt caagattact ggcgcgaatg cgtagctcat cgctacgtgt gtgattctcg
    16741 ccgccgacgt cctgctgcgg gagccaggcc acggttaagg ctccgctcgg ccagggtttg
    16801 ccatcaagcg taatccgtgt gtccggaata taaaactgcc agcccggctg ctcgcggcta
    16861 atctgcgccg tcaggttatc gacagacaac gtatgcgtcg tgttatcgcc cagccagctt
    16921 gcgccgccct gtttcagcca gacgtcccct ccggcgattt cgcctttact gagcgtcatc
    16981 cagccttcca gactgaaacg cgccgtctgg agcgccacat tatcctgcat ccatttgccc
    17041 agccacggct tgacgtcaat atcgtcggcc tgtaaccaga ctctgccgtt atttagcaga
    17101 ccgtcgtcat cgcgtaaatc catccgcacc tgcatcacgc cgtgctgccc ggtcaggctg
    17161 gagaggctga cctcgccttc ggctcggtgc cgctctttgc cgtttagcca ggtaagttgt
    17221 gggatcgcca gttccgcgcg ttgtcctgaa agcgtcagaa aactgatttg gctatcgcgc
    17281 agatcgaaat gatcgaactg ccgcaggaaa agatcgctta aacggctggt ttcgatgcct
    17341 tcgccgtcgc tgctttgaag aggcgtgttg gtgcggaaat tgagttgcca gaaggtcagg
    17401 tcgcgaaact gccagcgcat gtgcaacagg ctttgccaga cgtccagcgc cagcgtaacg
    17461 cgttttatcg acagctcgcc gccatctttc agggcggcat gaatattatg cgcttccagc
    17521 gtagggccaa aattttgcca gcttgcggag agttggctgg cggccaccgg cacgccggtc
    17581 acggactcaa ttttattcag gatagctgga cgccaggcgt caagatgagg caacgccagg
    17641 cgcagcccgc taaccagcag cgctgcaatg acgatgagcg cggctccagt gagcaataaa
    17701 atccccggca atcgcctcac gcgtctctcc ttgtctgcca aaaaatacga ctcacccccc
    17761 ttgagggtat attgccggat ggcggcgctt gcgccttatc cggcctacat gcgctggtgc
    17821 tattactcaa ttacatcatt acgacgtcaa actgctcctg gttataaagc ggttcgacct
    17881 gaactttaac ctgtttgccg acaaagattt cgacttccgc cagcgcgtgt gattcttcgc
    17941 ctttcagcgc ttccgccacc gcaggagaag cataaaccag gaagcgatcg gagtcataag
    18001 cgtgatgaac acgtacaatt tcacgcatga tctcatagca gacggtttcc accgttttta
    18061 ccgtcccgcg gccatgacag gttggacact cgttacaaag cacatgttcc acgctttcac
    18121 gggtccgttt acgggtcatt tccaccagtc ccagcggcga aaaaccgtta atactggttt
    18181 tcacgcgatc cttacttaac gcctgttcca gcgaatgcag cacccggcgg cgatgatctt
    18241 cattattcat gtcgataaaa tcgataatga taatgccgcc cagattacgc aggcgtagct
    18301 ggcgggcaat ggcctgcgtc gcttcaatat tggtattaaa aatggtgtcg tcgagattac
    18361 ggtgtccgac aaacgcgccg gtattgatat ctaccgtcgt catcgcttcg gtttggtcga
    18421 taatcagata accgccagac ttgagttcaa ctttacgctc cagcgcgcgc tggatttcat
    18481 tttccacgtc ataaagatcg aagatcggct gatggccact gtaatgctcc agcttactgg
    18541 tcatttccgg gatgtattct gcggtaaact ccagcagcga ctcataggtc agacgtgagt
    18601 cgacgcgaat tcggtccaac tgcgcatcgg cgaaatcgcg cagcacgcgc tgcgccagcg
    18661 ccagttcgcc atacatctgg tagcgcgttt gcggacgctt tttgcgctcc atgactttcg
    18721 tccagacgcg cttgagatag gcggcgtcag acgcgagatc ctcttcacac acgccttccg
    18781 ccgcggtacg gataataaac ccgccctgtt cgtcgcagta ttccgccacc acctttttca
    18841 ggcgctcgcg ttcactttcg ctttcgatgc gctgggaaac gccaacgtgt gacgcgccgg
    18901 gcataaaaac aaggtaacgg gagggcaacg tgatgtccgt ggtcaaacgc gcgcctttcg
    18961 tgccgagcgg atctttcact acctgcacca tcagatcctg tccctgacgc accagttcgg
    19021 agatatcgcg cacggtaaac tgtttttgct cgtcgcccgc cacgcattcg gtatgcggca
    19081 taatgtcgga agcgtgaaga aatgcggctt tatccagccc aatatctaca aaagccgcct
    19141 gcatacctgg aagtacacga cttacacgac ctttgtagat attgcctacg attccgcgtc
    19201 gcgcttcgcg ctcaatatgg atttcctgaa gaataccgcc atcaatgtac gccacgcgcg
    19261 tttccgatgg cgttacgttt accaacaatt cagccgtcat gtttatccct tttatcacgc
    19321 agtgcgttaa aatgactcaa caactcatac gtttcaacca gcggtaagcc gaccacggcg
    19381 tgatagctgc catttatctt cctgacaaaa cagccacccc gcccctgaat accgtatgca
    19441 cctgctttat ctaaaggctc gccgctggcg acatagccag taatatcctg cgcagaaagc
    19501 gtgcggaaag tcacctccgt taccaccaga caatccagcg tctgctgcga gtccgcaagc
    19561 gcaacagcag tcatcacctg atgcgtattt ccggaaagca aacgcagcat ttctgcggca
    19621 tgagcggcgt cgcgcggctt ttccagcacc tcgccgttta acacgactat cgtatccgcg
    19681 cccaacaccg gcagatcacg gggaaccagc gccacgccag cctgcgcctt ttcgcgcgcc
    19741 agccgaacaa catactgctg cgcgctttcc tgaacacgcc gttgctcttc aataccaggc
    19801 acgacctgct cgaatgaaaa tccaagttga atcaataatt cctggcgacg cggggaaccg
    19861 gaagcaagat acagagttgt catatcgacc tttattgcac agcaaactgc tggcgtactt
    19921 tacgcatcag caaaaagagc cagggccaca gcacgccatt gactacacta ctccagaaca
    19981 cttccggtct gaaagagacg ttgatcacta aaaactcggc ccagaaaaca ataatgtcca
    20041 cggccagtga aagcaacatt accaccagcg cctgctgcca gagcgccagg ttacggaaga
    20101 gctggaattt cagagcgacc agataggcga caatgctcat cgacagagcg cgcacgccaa
    20161 gtgtggaacc gctgatgaga tcaagtatgg cacccatcac aaatcccgtc cccacattta
    20221 cgcggtgcgg cagggccaga atccagtaca gtaagatgag caaaacccag tttggccgga
    20281 aaacaatgat gtcgtccggc cagggcatga tttgcagcaa cagcgcaata agaaacgaga
    20341 gccagataac ccagcgcccc tggctacgat agctcgccac cattaccctc ccggcgcacg
    20401 cgcagacggc gtggtcgcgc ccgaaggcga tgattgcgtt gataccggcg tagtctggcc
    20461 cgcagatggc tgagtaatcc ccgtcgccgg gtccggcact ggcgccggcg gccccatcgc
    20521 atccggagaa ggtaacacct gcggcatcat ctgcatcagg cgctcattgg cgacgcggtg
    20581 aacctcttcc ggcgtcatcg gattggcgcc gttacgatcg gctccccaca acagcagcag
    20641 atagcgtaaa cgctgcaaac ccgcggttgg acgagcctga atgacggtat aggcgcgctg
    20701 agtgtccagc ttgacggagg agaccaccgc caccggatac ccttccggga aacgcccacc
    20761 aagtccggac gttaccagca catcgccaac gcgaatatcg gtattggcgg gcagatgttc
    20821 aagctgaaga tcgtcagtgc agccgttacc ggcggcaatc acgcggatgt cattgcgtag
    20881 tacctgaatc ggcagagcat gagtcgcatc gcaaatcagc aatacgcggc tggtcagttt
    20941 cgccacggcg acaacctgcc ctacgacacc tttgtcgcta atgaccggtt gaccttcata
    21001 tacgccatta acgctgcctt tatcgataac gacctgatcg ctgtaaggat cgttaaccgt
    21061 tgaaataacc tgcgtcacca ttttctgctc gtcctgacgc agcggcgacc ccagcagctc
    21121 gcgcaaccgc gcgttctcct gtttgtactg ccccagcatc agcaggtcgc tgttttttag
    21181 cagtaattcc tggcgcagcg cccggttttc cagctcaagc tggtcgcgag aagccagcgt
    21241 ttgcgacacg ctgtcgagca gttcacgagg gccgtttgaa ataaaataga aaggactgac
    21301 ggcagtgtcc atgtacgttc ggatttgact gaacgtcccc aggcggctgt cggcaatgat
    21361 aacgccgagc gccaccagca ccgccagaat aaggcgaatc tgtagcgacg ggccacggct
    21421 aaaaattggc ttcataggct atgcgtattc tcgcgtcgga gaggcaggac aatccaggga
    21481 taatcctgcc cgtatccaac tactcttcgc tgaacaggtc gccgccgtgc atatcgatca
    21541 tttccagcgc cttgccgccg ccgcgcgcca cacaggtcag cggatcttca gcaaccacga
    21601 caggaatgcc cgtctcttcc attaacagac ggtcaaggtt acgcagcagc gcgccgccgc
    21661 cggtgagcac cataccgcgc tcggagatgt ctgacgccag ctccggcgga cactgttcca
    21721 gcgccaccat taccgcgctg acgataccgg tcaacggttc ctgcaacgct tccagaatct
    21781 cgtttgagtt cagggtaaag ccgcgtggaa cgccttccgc caggttacgg ccacgcactt
    21841 cgatctcgcg gacttcgtcg cccggataag cggaaccgat ttcgtgttta atacgttctg
    21901 cggtggcttc accaatcaga gaaccgtagt tacgacgaac gtaattaatg atggcttcgt
    21961 cgaagcggtc accaccaata cggacagaag aagagtaaac cacgccgttc agggagatca
    22021 cggcaacttc agtggtacca ccaccgatat ccacaaccat tgaaccggtt gcttcagaaa
    22081 ctggcagacc tgcgccgatc gcggccgcca tcggctcttc gatcaaaaag acttcacggg
    22141 cgcctgcgcc ctgagcggat tcacgaatcg cgcggcgttc tacctgcgtc gcgccgaccg
    22201 gcacgcatac cagtacgcgc gggcttgggc gcataaagct gttgctgtgc acttgtttaa
    22261 taaagtgctg gagcattttt tcggtcacaa agaagtcagc gataacgcca tctttcatcg
    22321 gacggatcgc agcgatattg cccggcgtac ggcccagcat ctgcttcgca tcatgaccga
    22381 ctgcagccac gcttttcggc gaaccggcac gatcctgacg aatggccaca acggaaggct
    22441 cattcaatac gatgccttgt ccttttacat aaatgagggt attcgcggta cccaggtcaa
    22501 tggacaggtc attggaaaac atgccacgaa attttttcaa catactaagg gataatcctg
    22561 aaagctgggg cggaaaacaa aatccgctta ctttaccaac cacacgcagc agcgacaagg
    22621 cgcaaaaatc atctgctacg gtgaaaatta gtgcagttcg tttcctttgt tacaaatctc
    22681 ggcctgagtc cctcagggct gaaaaaatca gcagcaatcc tcgccttcgt ttgcaacctg
    22741 tcaaaggtca ttcacctgca tatttgctgc aacaatctgg cgagcagaca agcacacccc
    22801 catgaggcgc agcgcgcgtt attctacgtg aaaacaaatt aaacggcagg ttaaaccgag
    22861 tatctttgcg aatatttttt cacgtttgtg tcaagtagtt gggaggaggc aaaaaaatca
    22921 ccctgcccgc cagccacgcc gcgttttgtc agcgtctgcc actcgccgcg cgaacggacg
    22981 cccgtcgcgt aaacctgcgt aggcgtgccc gcgcaggcct ctaccagact ttgaaccaga
    23041 agctggtttt ccgttcgctt ctcaatgttt ctgaccagac tcggatgcag cttgagtaat
    23101 tccacattga gcgctttaat ccagctcgtg ctaaccagcg tcaaacccgc ctgtgtcacc
    23161 gccacccgaa cgccaagcgc attgactaag cgaaggatgg gttgtaaccg gctgatgtgt
    23221 tgacaaacat ctgcctccgc aagttcaata attatgcgat ttcgctgtga tttttcacac
    23281 tgcattaacg tatcgcgcaa ccagcgctga aaacgcggac gaatcagcga ctcaaccgtc
    23341 aactgcattg ccagattttc atccggccag tagcccagca acgtaatcag gcggctaatt
    23401 tgtaatctgt catactcttc cgataaacca aattgcaaca ccatcggcat atactccgcc
    23461 gagctcacct cttctttacc gtcatagatg cgacacatca attcccgatg atgtacgcga
    23521 ccttctcgcg tgaccgccgg tttttgataa agtcgcggtc cgccccggtt cagcatctgc
    23581 tcaatcaatg tgcgccagcg cacattgccg cgcccttttt ccggcagagt gtcgtcgtag
    23641 atagcccagc tatttccccc ctgcagggcg gcattccgcg ccgcggcttc agcatgttcc
    23701 atcacctgat cggtggactg tccgctgcgc caggcgcaaa tgccgatatg taccatatcg
    23761 tcacgatcga gcattttgtt agccggtagc gcatcgacag cttttaaaag ttgtccggca
    23821 atactttccg cttctttcag cgttcgatgc ggtagcagca cggcaaagtc gctgcggtga
    23881 taacgcgcca gcagcgagcc tgggtaacgc ataatgaatg tcgatagcag attgataagc
    23941 ataaacatct gctcttccgc ctgattgcct cccaggctgt cgcgcagaag attgaagtct
    24001 ggcaagcgga tcatcatcac cacgccatgc actcccactt tttcctgatc ttccagcagc
    24061 gtcgccagct ggttatcaaa gaacagacgg ttaccgagtc cggttttggt gtcctgcgcg
    24121 gcgtaggagc gaatgagggt gtccaggcga ctacgctgtt cgtgagcaaa ctgaatttcg
    24181 gaaagcaata catcaagcgc gctactggtg cgcgctggcc attcgtaaac agaaccgcgg
    24241 acattcgccc cgcgttcgcc gttcagaata cgcgttgagc gaatttccag aagctcctgc
    24301 ccggaaagct gccgctgcag ccagcgcacc gataaaaaca aaatcagaac gataaaaccg
    24361 atcgccagcg tcagcggcgc cgtggtgatc agtgagtgaa aataattacc catcgggtcc
    24421 tgataaacca gacgtagcga cattcctgga tgttttatca gcggtacgac cagctcgcga
    24481 tacatgtcgc tggtgccggc tggccgataa cctctggcgc gagaatggct gtagacgctg
    24541 cgctccccct gcaacagatc gacacgcaca atatcggaag cgatcatgag ctcgtcgatt
    24601 tgcggcgtca gcgagacaat atcatgggtc accaggtgcg tatcaatggc tgttgccgtc
    24661 gcctgcacac ggctgacata cttatactgt acggcgttat aaaagcttag cgagcaacct
    24721 atcagagtca cgaagatcgt taatcccgtg agcagcgtga taaaagctga gaatttcgtc
    24781 gttaatcgca tccttgagtt aactccgacg gttataaaca gtatgaaaaa gcgaatctga
    24841 aggcggaatt cgccacggcg cgcaatgaag caggcatact accaaaatgg atctatctgg
    24901 caatttattg cgttgcatcg gcatcacgtt ttaattagcg agtatagtct tcgtagctat
    24961 ttttccaatc taccatgtaa agtgaggaca ggttatgcag gcgttgatct tagaacagca
    25021 ggacggtaaa accctcgcat ccgtgcaaca tctcgaagag agtcaactgc cggcaggtga
    25081 tgtgacggtg gatgtccact ggtccagcct gaattataaa gatgctctgg ctatcaccgg
    25141 aaaagggaaa attatccgtc attttccgat gattcctggt attgatttcg ccggcaccgt
    25201 tcacgcaagc gaagatcctc gctttcatgc aggccaggaa gtactactga ctggctgggg
    25261 cgtgggcgaa aaccactggg gcggcctggc cgaacgcgca cgcgttaaag gcgactggct
    25321 ggtcgcgctg cctgcgggac tgagcagccg taacgccatg atcatcggca ccgccggttt
    25381 taccgccatg ctgtgcgtca tggcgcttga agatgcaggt attcgcccgc aagacggtga
    25441 ggttgtcgtc accggcgcca gcggcggtgt gggcagcact gccgttgcat tactgcataa
    25501 gctgggctat caggttgcag cagtatcagg acgtgaaagc acccacggct atcttaagag
    25561 cctgggagct aaccgtattc tcagccgcga tgagtttgct gaatctcgcc cgttggaaaa
    25621 acagctgtgg gccggtgcaa ttgataccgt tggcgataaa gtgctggcga aagtcctggc
    25681 acagatgaac tatggcggtt gcgtggccgc ctgcggcctg gcgggcggct tcgcgctgcc
    25741 gaccaccgtt atgccattca ttctgcgtaa tgtgcgtttg caaggggtgg actcggtgat
    25801 gaccccaccg gcacgtcgcg cagaagcctg ggcgcgtttg gttaaggatc tgccggaatc
    25861 gttctatgct caggccgcca cagagattac gctggcggat gcgccgaagt tcgccgatgc
    25921 catcatcaat aatcaggttc agggccgtac gctggtgaag ataaaataac gtcacgtata
    25981 aaaaaattta cacttaatta cctatttatt tttacacatt gacacactcc ctattatatt
    26041 cactacacgc catgttgtgg tgggtagacc gggagtctgt gatgaaaaag atacgtccat
    26101 taacagaagc cgatgtgact gcggaatcgg ctttttttat gcagcgccga caggtgctaa
    26161 aagcattagg catcagcgcg gccgccttat ccttaccctc aacggcgcag gccgatctct
    26221 tcagttggtt taaaggcaac gatcgtccga aagcgcctgc cggtaaaccg cttgagttta
    26281 gtcagcctgc cgcctggcga agcgatttag cgttaacgcc ggaagataag gtgacgggct
    26341 acaacaattt ctatgagttt ggccttgata aagccgaccc ggcggccaat gccggaagtc
    26401 tgaaaaccga accgtggacg ttgaaaatca gcggggaagt cgcgaaacca tttacgctgg
    26461 attacgacga tttaacacat cgttttccat tagaagagcg tatctatcga atgcgctgcg
    26521 tcgaagcgtg gtccatggtc gtgccgtgga ttggtttccc tttatataag ctactcgcgc
    26581 aggcacagcc caccagccac gctaaatatg tggcattcga aacactatac gcgccggatg
    26641 atatgccagg acagaaagat cgctttattg gcggcggact gaaataccct tatgtcgaag
    26701 ggctacgtct ggacgaagcc atgcatccgc tgacgctgat gaccgttggc gtctatggta
    26761 aagcgttacc cccgcaaaac ggcgcgccca ttcgcctcat cgttccatgg aagtatggtt
    26821 ttaaaggtat taaatctatt gttagcatta aactcacccg cgaacgtccg ccaaccacct
    26881 ggaatttgtc ggctcccaac gaatatggtt tttatgccaa tgtgaacccg catgtggatc
    26941 atccacgctg gtctcaggct accgaacgct ttattggttc aggcggtatc cttgatgtgc
    27001 aaaggcagcc gacgctgctg tttaacggct acgccaatga agtcgcttcg ctgtatcgcg
    27061 gtctcaattt gcgggagaat ttttaagtgc gtctgacagt aaaacagata acctggctaa
    27121 aagtttgtct gcatcttgcc ggttttttgc cgcttctgtg gctcttttgg gcgataaatc
    27181 acggtggact cagcgcagac ccggtaaagg atatccaaca ctttaccggt agaaccgcgc
    27241 tcaaattttt gctcgccacc ttgctggttt caccgctggc gcgctacgct aaacagccat
    27301 tattgatacg cacacgccgc ctgttaggat tatggtgttt cgtttgggcg acactgcatt
    27361 taaccagcta tgccttgctg gaactgggga tacataacct ggcgctgtta ggaagcgagt
    27421 tgatttcacg cccttatttg acgcttggga tcattagctg gctggtgtta ttggcgctga
    27481 cgttgacctc aacgcaattt gcgcagcgta aattgggcaa acgctggcaa acactgcata
    27541 acgtcgtcta tcttgtcgcg atcctggctc ccatacatta cctgtggtcg gtaaagattt
    27601 tatcaccgca accggtcatc tacgcggcat tagcgttagc ccttttagcg ttgcgttacc
    27661 ggaagtttcg ccagtggtgg cgctagtttg gtgaactgtg cggtcgattg caaaacgcaa
    27721 aacaggtaat gtccttttta tgtttcgggt tgattatctt ccctgataag accagtattt
    27781 agctgccaat tgcgacgaaa tagttataat gtgcgacttt acattcccca acggcgattt
    27841 tcgttcgcag ataagggtga caatcgtgca atgaaggtat attttgtttt ttgcccgaaa
    27901 atggcagaag atagccacac aatgactggc aaatcatgaa tttcaccttc gggtgctacg
    27961 gcataacagg caaatcaaag atgcgcggta ttttacccgc ggcagtcatt cacatgcttt
    28021 acagacggcg ctaaaacgcc tgtcacaatc acactaaaca aagagtacgg aacccactca
    28081 tggatattcg taagattaaa aaactgatcg agctggttga agaatcaggt atctccgaac
    28141 tggaaatttc tgaaggcgaa gaatctgttc gcatcagccg cacaacggca aacgccggtt
    28201 tcccggtgat gcagcaggct tatgcggcgc cgatgatgca gcaacccgct ctgtctaacg
    28261 ctgtcgcgcc agcggctact ccagcaatgg aagcgcctgc cgcagcggaa atcagtggtc
    28321 acatcgtacg ctccccaatg gttggtactt tctaccgcac cccaagcccg gacgcgaaag
    28381 cgttcatcga agtgggccag aaagtgaacg tgggcgatac cctgtgcatc gttgaagcca
    28441 tgaaaatgat gaaccagatc gaagcagaca aagcaggcac tgtgaaagcg attctggtcg
    28501 aaagtggtca accggtagaa tttgacgagc cactggtcgt catcgagtaa cgaggcgaac
    28561 atgttggata aaattgtcat cgccaaccgc ggcgagatcg cactacgtat tcttcgagcc
    28621 tgtaaagaac tcggcatcaa gaccgtcgct gtgcactcaa gcgcggatcg cgatttaaaa
    28681 cacgtattgc tggcggatga gacggtctgt attggcccgg caccgtccgt aaaaagttat
    28741 ctgaacatcc cggctatcat tagcgccgct gaaatcaccg gcgcggtggc aatccacccg
    28801 ggttacggct tcctttctga gaacgccaat tttgccgagc aggttgaacg ctccggcttt
    28861 atctttatcg gcccgaaagc ggacaccatc cgcctgatgg gcgataaagt gtccgcgatt
    28921 accgcgatga aaaaagcggg cgtgccgacc gtaccaggat ctgacggccc actgggcgac
    28981 gatatgaatg cgaaccgcgc tcatgccaaa cgtattggct atccggtgat catcaaagcg
    29041 tccggcggcg gcggcggccg cggtatgcgc gtggttcgta gcgatgctga actggcgcag
    29101 tccatctcca tgactaaagc ggaagcgaaa gcagctttca gcaacgacat ggtatacatg
    29161 gaaaaatacc tggaaaatcc acgccacatc gaaattcagg tgctggcgga cggccagggc
    29221 aacgctatct atctggcgga acgcgactgc tccatgcagc gtcgccacca gaaagtggtt
    29281 gaagaagccc cggcgccagg cattacgccg gaactgcgtc gctatatcgg cgaacgctgc
    29341 gcgaaagcgt gcgtagacat cggctatcgc ggcgcaggaa cgttcgaatt cctgttcgaa
    29401 aacggcgagt tctatttcat cgaaatgaac acccgtattc aggttgaaca cccggtaact
    29461 gaaatgatta ccggcgtcga tttgatcaaa gagcagttgc gcatcgcggc gggtcagcca
    29521 ctgtcgatca cacaggacga agttgtcgtt cgaggccatg cggtagaatg ccgtatcaat
    29581 gccgaagatc cgaacacctt cctgccaagc cctggcaaaa tcacgcgctt ccatgcgcct
    29641 ggcggctttg gcgttcgctg ggaatctcat atctacgcgg gctacacggt gccgccgtac
    29701 tatgattcca tgatcggcaa actcatctgc tacggtgaaa accgcgacgt ggcgattgcc
    29761 cgtatgaaaa atgccctgca ggaactgatt atcgatggta tcaaaaccaa tatcgatctg
    29821 cagacccgca tcatgaatga cgagcacttc cagcacggtg gaaccaacat ccactatctg
    29881 gagaaaaaac tcggtcttca ggaaaagtaa tcgcacgtta atctcaaaag gccggtgaat
    29941 ccggcctttt ttatttctgg ggatagcgat gccccatcat gtacaattcc cgctttcttc
    30001 acccataagg gacaaaaaat ggacgctcgt tttgttcagg cccataaaga ggcgcgctgg
    30061 gcgctgtggc tgaccctttg ctatctggcg gcatggttag tggctgctta cttatctgga
    30121 gactcgccgg gaattaccgg tctgccgcac tggttcgaga tggcctgctt attgacgccg
    30181 ctggtcttta ttttgctgtg ctgggcgatg gtgaaattca tttatcgcga tattccgctg
    30241 gaggatgacg atgcagcttg aggtcattct accgctggta gcctatctgg tcgtggtctt
    30301 cggggtctcg atttacgcta tgcgcaagcg taccgccggc acctttttaa acgagtattt
    30361 tcttggcagt cgttcgatgg gcgggatcgt gctcgcgatg acgctgaccg ccacctatat
    30421 tagcgccagt tcatttatcg gcggtcccgg cgcggcttat aaatatggtc tgggctgggt
    30481 cttgctggcg atgatccagc ttcccgccgt ctggctttca ctgggtattc tgggtaaaaa
    30541 attcgctatc ctggcgcgtc gctataatgc cgtcacgctt aacgatatgc tattcgctcg
    30601 ttaccaaagc cgcctgctgg tgtggttagc aagcctgagt ttattggtcg cgtttattgg
    30661 cgcaatgacc gtacaattta tcggcggcgc gcgactactg gaaaccgcgg cgggaattcc
    30721 ctacgaaacc ggcctgctaa tatttggcgt cagtatcgca ctctatacgg cgtttggcgg
    30781 ctttcgcgcc agcgtactta acgatacgct acagggcctg gtgatgctgg tcggcacgat
    30841 agtgctgctg gtgggcgtgg tgcatgcggc gggcggttta catcaggccg ttgacacgct
    30901 gcacgctctc gaccccaaac tggtaacgcc gcagggcgcc gatgacatac tttctcccgc
    30961 ttttatgacc tctttttggg tactggtctg ttttggcgtg attggcctgc cgcatacggc
    31021 agtgcgctgc atttcttata aagacagtaa agcggtacac cggggcatta ttatcggtac
    31081 gattgtcgtg gcgattttaa tgttcgggat gcaccttgcc ggcgcgctgg gtcgcgcggt
    31141 gcttccggat ctgacggtgc cggatctggt gatcccaacg ctaatggtga aagttttgcc
    31201 gccgtttgcc gccgggatct tccttgctgc gccaatggcg gcgatcatgt caacaattaa
    31261 cgcccaactg ctgcaaagtt ccgcgacgat cattaaagat ctctatctca acctgcgtcc
    31321 cgatcagatg caaaatgaga tccggctgaa gcgtatgtcg gcagcgatta cattactgtt
    31381 aggcgcgctg ttgctgctgg ccgcgtggaa accgccagag atgatcattt ggctcaacct
    31441 gctggcgttt ggcggcctgg aagcggtgtt cttatggccg ctggtactgg gcctttactg
    31501 ggagcgggca aacgcggcag gcgcgttaag cgccatgatc gtgggcggcg tgctatatgc
    31561 cctgcttgcc acatttaata ttcagtacct gggctttcat ccgattgtgc ccgcgttact
    31621 gttaagttta ttggcttttc tgatcggaaa ccgattcggc tcttccgctt cgcaagccac
    31681 cgtattgtct actgataaat aaagagtttt gccatgccat ggatccaatt gaaactgaat
    31741 accaccggcg cgaatgctga agagctaagt gatgcgctga tggaagcggg cgccgtttcc
    31801 attacctttc aggatacaca cgatacgccg gtttttgagc cgttgccggg cgaaacccgt
    31861 ctgtggggcg ataccgatgt gatcggtctg ttcgacgccg aaacagacat gaaagacgtt
    31921 gtcgcgattc tggagcaaca tccactgctg ggtgccggat ttgcccataa aatcgaacaa
    31981 ctggaagata aagactggga acgcgaatgg atggataatt tccatccgat gcgttttggc
    32041 gagcgtctgt ggatttgtcc cagctggcgt gacattccgg acgagaatgc cgtcaacgtg
    32101 atgctcgacc cgggactggc gttcggtacg ggtacgcacc ccaccacctc tttatgtctg
    32161 caatggctgg acgggctcga tctcaacggc aaaaccgtga tcgactttgg ctgcggttca
    32221 ggcattctgg cgattgccgc gctgaagctg ggagcggcaa aggcgattgg tattgatatc
    32281 gatccgcaag ctattcaggc cagtcgcgat aatgccgaac gtaacggcgt gtctgaccgg
    32341 ctggagctgt acctgccgaa agaccagcca gaagccatga aagccgacgt ggtcgtcgct
    32401 aacatcctgg caggcccatt acgcgaactg gccccgttaa tcagcgtact gcccgttgag
    32461 ggcggtctgc tggggctttc aggtattctc gccagccagg cggaaagcgt ctgtgatgct
    32521 tacgccgagc ttttcactct cgacccggtc gtcgaaaaag aagagtggtg ccgcattact
    32581 ggccgtaaga aataattctt gtcagcgtgg tcgcccggcc acgcttttct ccacacaact
    32641 gccttaacgc ctttcaggca ccgagacatc attaaattca tcaaatgaat gcctgaaata
    32701 acttctttgt cactatccgt ctggataaac agctgctacc agcggacaaa cgtactggcg
    32761 cttcaacggc ccgcagccat cgccctcgta cttagtaaat gctgtccggg ttgttctgca
    32821 gcatccgcta acgctctttt tagcgcagct ggaaaaattt atgcgtgccg ttcatgaaca
    32881 caaaagcgca tctgtgcacc ccttccgact ggcaatggag aaaaatcacg cgcagcggga
    32941 agtgatcttg tcctgaaacg agacggcgat cccattcatt tggggtaatt agcttataaa
    33001 aaaagcagat tattccgctt atcttgtttc tggtcgaaga aatagagaga agttacggga
    33061 atttgtaagc gcgtacaaaa
//
LOCUS       DAJVBX010000022        32930 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.022, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000022 DAJVBX010000000
VERSION     DAJVBX010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 32930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32930
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.022"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            7..1173
                     /locus_tag="OPV72_000947"
     CDS             7..1173
                     /locus_tag="OPV72_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016236132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mandelate racemase/muconate lactonizing enzyme
                     family protein"
                     /protein_id="HCR9913315.1"
                     /translation="MDVANDFASATSKWRPVVVKINTDEGISGFGEVGLAYGVGASAG
                     IGMAKDLAAIIIGMDPMNNEAIWEKMLKKTFWGQGGGGIFSAAMSGIDIALWDIKGKA
                     WGVPLYKMLGGKSREKIRTYASQLQFGWGDGSDKDMLTEPEQYAQAALTAVSEGYDAI
                     KVDTVAMDRHGNWNQQNLNGPLTDKILRLGYDRMAAIRDAVGPDVDIIAEMHAFTDTT
                     SAIQFGRMIEELGIFYYEEPVMPLNPGQMKQVADKINIPLAAGERIYWRWGYRPFLEN
                     GSLSVIQPDICTCGGITEVKKICDMAHVYDKTVQIHVCGGPISTAVALHMETAIPNFV
                     IHELHRYALLEPNTQTCKYNYLPKNGMYEVSELPGIGQELTEETMKKSPTITVK"
     gene            1288..2196
                     /locus_tag="OPV72_000948"
     CDS             1288..2196
                     /locus_tag="OPV72_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001054600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCR9913316.1"
                     /translation="MNLTIRQFRAFLAVADLRSFTAASKYLCITQGAVSGLINEMESQ
                     MEVSLFDRTSRVVKLSPDGEKFLPAAMRVVEEFQRAENYARDLKEIKKSLVRVVGAPL
                     IACAFLPQIIHAFKRQHPHTHVQLIDKPMSQLQKSIMLGEADFGIGPERPLEPEIDKQ
                     TLFTTEIALYCHPDYRLHKKTVRWEEIQSEELIAVGNESVPMISATAGVRIKPKMTVE
                     HMATAMSLAAQCEGVVIAETFSRHYAKSYQLATCSLTPPLRRNMNLYFHAWRAQTPAT
                     QRFKEFLFRYMDEHHDALASQRRAGD"
     gene            complement(2203..4617)
                     /gene="gyrB"
                     /locus_tag="OPV72_000949"
     CDS             complement(2203..4617)
                     /gene="gyrB"
                     /locus_tag="OPV72_000949"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HCR9913317.1"
                     /translation="MSNSYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVV
                     DNAIDEALAGHCKDIVVTIHADNSVSVTDDGRGIPTGIHPEEGVSAAEVIMTVLHAGG
                     KFDDNSYKVSGGLHGVGVSVVNALSQKLELVIQRDGKIHRQIYEHGVPQAPLAVTGDT
                     DKTGTMVRFWPSHETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHY
                     EGGIKAFVEYLNKNKTPIHPNIFYFSTEKDGIGVEVALQWNDGFQENIYCFTNNIPQR
                     DGGTHLAGFRAAMTRTLNAYMDKEGYSKKAKVSATGDDAREGLIAVVSVKVPDPKFSS
                     QTKDKLVSSEVKSAVEQQMNELLSEYLLENPSDAKIVVGKIIDAARAREAARRAREMT
                     RRKGALDLAGLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKI
                     LNVEKARFDKMLSSQEVATLITALGCGIGRDEYNPDKLRYHSIIIMTDADVDGSHIRT
                     LLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIALDGATL
                     HANAHAPALSGEALEKLVSEYNATQKMIGRMERRFPKALLKELVYQPTLTEADLSDEQ
                     TVTRWVNALITELNEKEQHGSQWKFDVHTNTEQNLFEPIVRVRTHGVDTDYPLDHEFV
                     TGAEYRRICTLGEKLRGLIEEDAFIERGERRQPVTSFEQALEWLVKESRRGLAIQRYK
                     GLGEMNPDQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRAFIEENALK
                     AANIDI"
     gene            complement(4646..5719)
                     /gene="recF"
                     /locus_tag="OPV72_000950"
     CDS             complement(4646..5719)
                     /gene="recF"
                     /locus_tag="OPV72_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HCR9913318.1"
                     /translation="MSLSRLLIKDFRNIENADLALSPGFNFLVGANGSGKTSVLEAIY
                     TLGHGRAFRSLQPGRVIRHEQEAFVLHGRLQGEERETSIGLTKDKQGDSKVRIDGTDG
                     HKIAELAHLMPMQLITPEGFTLLNGGPKYRRAFLDWGCFHNEAGFFTAWSNLKRLLKQ
                     RNAALRQVSRYEQLRPWDKELIPLAEQISTWRAEYSSAIAQDMADTCQQFLPEFSLTF
                     SFQRGWEKETDYADVLERSFERDRMLTYTAHGPHKADFRIRADGAPVEDTLSRGQLKL
                     LMCALRLAQGEFLTRESGRRCLYLIDDFASELDDARRGLLASRLKATQSQVFVSAISA
                     EHVIDMSDENSKMFTVEKGKITD"
     gene            complement(5917..7017)
                     /gene="dnaN"
                     /locus_tag="OPV72_000951"
     CDS             complement(5917..7017)
                     /gene="dnaN"
                     /locus_tag="OPV72_000951"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006177590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HCR9913319.1"
                     /translation="MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSL
                     TGTDLEMEMVARVTLSQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGDRMLVRSG
                     RSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLF
                     ETEGSELRTVATDGHRLAVCSMPLEASLPSHSVIVPRKGVIELMRMLDGGENPLRVQI
                     GSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDILKQAFARAAILSNE
                     KFRGVRLYVSENQLKITANNPEQEEAEEILDVSYGGTEMEIGFNVSYVLDVLNALKCE
                     TVRIMLTDSVSSVQIEDAASQSAAYVVMPMRL"
     gene            complement(7022..8422)
                     /gene="dnaA"
                     /locus_tag="OPV72_000952"
     CDS             complement(7022..8422)
                     /gene="dnaA"
                     /locus_tag="OPV72_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HCR9913320.1"
                     /translation="MSLSLWQQCLARLQDELPATEFSMWIRPLQAELSDNTLALYAPN
                     RFVLDWVRDKYLNNINGLLNTFCGADAPQLRFEVGTKPVTQTLKTPVHNVVAPTQTTT
                     AQPQRVAPAARSGWDNVPAPAEPTYRSNVNVKHTFDNFVEGKSNQLARAAARQVADNP
                     GGAYNPLFLYGGTGLGKTHLLHAVGNGIMARKPNAKVVYMHSERFVQDMVKALQNNAI
                     EEFKRYYRSVDALLIDDIQFFANKERSQEEFFHTFNALLEGNQQIILTSDRYPKEING
                     VEDRLKSRFGWGLTVAIEPPELETRVAILMKKADENDIRLPGEVAFFIAKRLRSNVRE
                     LEGALNRVIANANFTGRAITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKIAD
                     LLSKRRSRSVARPRQMAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKIEQLREES
                     HDIKEDFSNLIRTLSS"
     gene            9083..9223
                     /gene="rpmH"
                     /locus_tag="OPV72_000953"
     CDS             9083..9223
                     /gene="rpmH"
                     /locus_tag="OPV72_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001686914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HCR9913321.1"
                     /translation="MKRTFQPSVLKRNRSHGFRARMATKNGRQVLARRRAKGRARLTV
                     SK"
     gene            9240..9599
                     /gene="rnpA"
                     /locus_tag="OPV72_000954"
     CDS             9240..9599
                     /gene="rnpA"
                     /locus_tag="OPV72_000954"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014172301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HCR9913322.1"
                     /translation="MVKLAFPRELRLLTPAHFTFVFQQPQRAGTPQITILGRLNSLGH
                     PRIGLTVAKKNVRRAHERNRIKRLTRESFRLRQHELPAMDFVVVAKKGVADLDNRALS
                     EALEKLWRRHCRLARGS"
     gene            9563..9820
                     /gene="yidD"
                     /locus_tag="OPV72_000955"
     CDS             9563..9820
                     /gene="yidD"
                     /locus_tag="OPV72_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HCR9913323.1"
                     /translation="MAPPLSPGSRVLIALIRVYQRLISPLLGPHCRFTPTCSSYGIEA
                     LRRFGVIKGSWLTVKRVLKCHPLHPGGDDPVPPGPFDTREH"
     gene            9823..11469
                     /gene="yidC"
                     /locus_tag="OPV72_000956"
     CDS             9823..11469
                     /gene="yidC"
                     /locus_tag="OPV72_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HCR9913324.1"
                     /translation="MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQTQQTMQTTTTAA
                     GSAADQGVPASGQGKMITVKTDVLDLTINTRGGDVEQALLPAYPKELGSNEPFQLLET
                     TPQFIYQAQSGLTGRDGPDNPANGPRPLYNVEKDAFVLADGQNELQVPMTYTDAAGNT
                     FTKTFVFKRGDYAVNVNYSVQNTGEKPLEVSTFGQLKQSVNLPPHRDTGSSNFALHTF
                     RGAAYSTPDEKYEKYKFDTIADNENLNVSSKGGWVAMLQQYFATAWIPRNDGTNNFYT
                     ANLGNGIVAIGYKAQPVLVQPGQTGAMTSTLWVGPEIQDKMAAVAPHLDLTVDYGWLW
                     FISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQA
                     MRERLGDDKQRQSQEMMALYKAEKVNPLGGCFPLIIQMPIFLALYYMLMGSIELRHAP
                     FALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQKIMTFMPVIFTVFFLW
                     FPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGLHSREKKKS"
     gene            11611..12975
                     /gene="mnmE"
                     /locus_tag="OPV72_000957"
     CDS             11611..12975
                     /gene="mnmE"
                     /locus_tag="OPV72_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HCR9913325.1"
                     /translation="MSHNDTIVAQATPPGRGGVGILRISGLKARDVAQEVLGKLPKPR
                     YADYLPFKDVDGSALDQGIALWFPGPNSFTGEDVLELQGHGGPVILDLLLKRILTLPG
                     VRIARPGEFSERAFLNDKLDLAQAEAIADLIDASSEQAARSALNSLQGAFSARVNHLV
                     EALTHLRIYVEAAIDFPDEEIDFLSDGKIEAQLNGVIADLDAVRTEARQGSLLREGMK
                     VVIAGRPNAGKSSLLNALAGREAAIVTDIAGTTRDVLREHIHIDGMPLHIIDTAGLRD
                     ANDEVERIGIERAWQEIEQADRVLFMVDGTTTDAVDPADIWPDFIARLPKNLPITVVR
                     NKADITGETLGISEVNGHSLVRLSARTGEGVDVLRNHLKQSMGFDTNMEGGFLARRRH
                     LQALAEAANHLEQGKAQLLGAWAGELLAEELRLAQQSLSEITGEFTSDDLLGRIFSSF
                     CIGK"
     gene            13158..14345
                     /locus_tag="OPV72_000958"
     CDS             13158..14345
                     /locus_tag="OPV72_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001608974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR9913326.1"
                     /translation="MKRFLLCSFALVLLYPAGIDMYLVGLPRIAADLNASEAQLHIAF
                     SVYLAGMATAMLFAGKIADQSGRKPVAIVGAIVFMMASLLCSRASEGSLFLSGRFLQG
                     VGAGGCYVVAFAILRDTLDEHRRAKVLSLLNGITCIVPVLAPVMGHLIMLRFPWQSLF
                     YTMSTMGIMVGLLSLFILRETRPARLAPRDLSPSSSAAESLVNRFFVSRLAITTLSVS
                     VILTFVNASPVLLMEVMGFSRGDYAITMALTAGVSMVVSFSTPFALGLFKPRTLMLVS
                     QGLFLTAGVTLSLAHTNTVTLFGLTLICAGFSVGFGVAMSQALGPFSLRAGVASSTLG
                     IAQVCGSSLWIWLAAILGISAMNMLIGILIGCSIVSILLIFSVAPNRSVAEHEEIPYQ
                     SRS"
     gene            14314..15273
                     /gene="yidZ"
                     /locus_tag="OPV72_000959"
     CDS             14314..15273
                     /gene="yidZ"
                     /locus_tag="OPV72_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator YidZ"
                     /protein_id="HCR9913327.1"
                     /translation="MKKSLTSLDLNLLLCLQLLMQERSVTKAAKRMNVTPSAVSKSLA
                     KLRAWFDDPLFVNTPLGLAPTPLMVSMEQSLADWMQMGNQLLDKPHHQTPRGLKFELA
                     AESPLMMIMFNSLSQQIYQRYPQATIKVRNWDYDSLEAITRGKVDIGFTGRESHPRSR
                     ELISLLPLAIDFEVLFSDLPWVWLQEDHPALREAWDLDTFLRYPHISICWEQSDTWAL
                     DDVLQEMGRKRHIALSLPGFEQSLFMAAQPGHTLIATAPRYCQHYNQLHQLPLVARPL
                     PFDAQQREKLMVPFTLLWHKRNSHNPKIVWLRQAINTLCRRLI"
     gene            15431..16186
                     /locus_tag="OPV72_000960"
     CDS             15431..16186
                     /locus_tag="OPV72_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="HCR9913328.1"
                     /translation="MATHFARGILTEGQLVSIRLSSSCHIEARNLPAHRRTRFLASRG
                     LLAELMFMLYGISELPEIIIQAKGKPAFRDKNLPGFSISYAGNMVGVALTTEGECGLD
                     MELQRTSRGFHHPHSLERHPFSRNENLWVANQNDPNEARAQLITLRQSVLKLTGDVMN
                     DDPRELQLLPVAGRLKCAHVTQLEAVCDAEDVLVWSVTVTPAIEKLKVWEFDGKLGWK
                     SLPDIQTRANEPTGRLMRFAQLPAAKSYTLNRS"
     gene            16186..16770
                     /locus_tag="OPV72_000961"
     CDS             16186..16770
                     /locus_tag="OPV72_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462749.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HCR9913329.1"
                     /translation="MKKGARMSEMLNVVTLLGSLRKGSFNGMVARTLPKVAPAGMTVS
                     PLPSIGDIPLYDADIQQEEGFPASVEALAEQIRNADGVVIVTPEYNYSVPGGLKNAID
                     WLSRLPEQPLAGKPVLIQTSSMGAIGGARCQYHLRQILVFLDAMVMNKPEFMGGVIQN
                     KVDPQTGEVVDQGTLDHLTGQLTAFGEYIQRVKA"
     gene            complement(16815..18152)
                     /gene="adeP"
                     /locus_tag="OPV72_000962"
     CDS             complement(16815..18152)
                     /gene="adeP"
                     /locus_tag="OPV72_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine permease AdeP"
                     /protein_id="HCR9913330.1"
                     /translation="MSQQHTTQASGQGMLERVFKLREHGTTARTEVIAGFTTFLTMVY
                     IVFVNPQILGVAGMDTSAVFVTTCLIAAFGSILMGLFANLPVALAPAMGLNAFFAFVV
                     VQAMGLPWQVGMGAIFWGAVGLLLLTIFRVRYWMIANIPVSLRVGITSGIGLFIGMMG
                     LKNAGVIVANPETLVSIGNLTSHSVLLGVLGFFIIAILASRNIHAAVLVSIIVTTLLG
                     WIMGDVHYNGIVSAPPSVTSVVGHVDLAGSFNLGLAGVIFSFMLVNLFDSSGTLIGVT
                     DKAGLADEKGKFPRMKQALFVDSISSVTGAFVGTSSVTAYIESSSGVSVGGRTGLTAV
                     VVGILFLLVIFLSPLAGMVPPYAAAGALIYVGVLMTSSLARVNWQDLTESVPAFITAV
                     MMPFSFSITEGIALGFISYCVMKIGTGRLRDLSPCVVIVALLFVLKIVFIDAH"
     gene            18321..18986
                     /gene="yieH"
                     /locus_tag="OPV72_000963"
     CDS             18321..18986
                     /gene="yieH"
                     /locus_tag="OPV72_000963"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate phosphatase"
                     /protein_id="HCR9913331.1"
                     /translation="MSQIEAVFFDCDGTLVDSEVICSRAYVTMFRQFGITLELTEVFR
                     RFKGVKLYEIIDTISKEHGVALAKAELEPVYRAEVARLFDTELEAIAGTNTLLESIKT
                     PMCVVSNGPVSKMQHSLGKLGMLHHFPDLLFSGYDIQRWKPDPALMLHAANAMKVNVE
                     KCILVDDSSAGAQSGIAAGMEVFYFCADPHNKPIDHPNVTTFTDLAQLPGLWKARGWK
                     ITR"
     gene            complement(19081..19806)
                     /gene="phoU"
                     /locus_tag="OPV72_000964"
     CDS             complement(19081..19806)
                     /gene="phoU"
                     /locus_tag="OPV72_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HCR9913332.1"
                     /translation="MDSLNLNKHISGQFNAELESIRTQVMTMGGMVEQQLSDAITAMH
                     NQDSELAKRVVEGDHQVNMMEVAIDEACVRIIAKRQPTASDLRLVMAIIKTIAELERI
                     GDVADKICRTALEKFSQQHQPLLVSLESLGRHTVQMLHDVLDAFARMDLDEAVRIYRE
                     DKKVDQEYEGIVRQLMTYMMEDSRTIPSVLTALFCARSIERIGDRCQNICEYIFYFVK
                     GQDFRHVGGDELDKLLAGKDPKE"
     gene            complement(19821..20594)
                     /gene="pstB"
                     /locus_tag="OPV72_000965"
     CDS             complement(19821..20594)
                     /gene="pstB"
                     /locus_tag="OPV72_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000063125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HCR9913333.1"
                     /translation="MSMVETAPSKIQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGP
                     SGCGKSTLLRTFNKMYSLYPEQRAEGEILLDGDNILTNTQDIALLRAKVGMVFQKPTP
                     FPMSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALWNETKDKLHQSGYSLSGGQQQ
                     RLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKQDYTVVIVTHNMQQAARC
                     SDHTAFMYLGELIEFSNTDDLFTKPAKKQTEDYITGRYG"
     gene            complement(20681..21571)
                     /gene="pstA"
                     /locus_tag="OPV72_000966"
     CDS             complement(20681..21571)
                     /gene="pstA"
                     /locus_tag="OPV72_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HCR9913334.1"
                     /translation="MATLDMQNTAQLAEFRRKMQARRRMKNRIALTLSMATMAFGLFW
                     LIWILMSTITRGIDGMSLALFTEMTPPPNTAGGGLANALAGSGLLILWATVLGTPLGI
                     MAGIYLAEYGRKSWLAEIIRFINDILLSAPSIVVGLFVYTIVVAQMQHFSGWAGVIAL
                     ALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASISGIMTGILLAI
                     ARIAGETAPLLFTALSNQFWSTDMMQPIANLPVTIFKFAMSPFAEWQQLAWAGVLIIT
                     LCVLLLNILARVVFAKKKHG"
     gene            complement(21571..22530)
                     /gene="pstC"
                     /locus_tag="OPV72_000967"
     CDS             complement(21571..22530)
                     /gene="pstC"
                     /locus_tag="OPV72_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008806729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstC"
                     /protein_id="HCR9913335.1"
                     /translation="MAATKPAFNPPGKKGDMIFSALVKLAALIVLLMLGGIIVSLIIS
                     SWPSIQKFGFSFLWTKEWDAPNDIYGALVPIYGTLVTSFIALLIAVPVSFGIALFLTE
                     LAPGWLKRPLGIAIELLAAIPSIVYGMWGLFIFAPLFATYFQEPVGNILSNIPFVGAL
                     FSGPAFGIGILAAGVILAIMIIPYIAAVMRDVFEQTPVMMKESAYGIGCTTWEVIWRI
                     VLPFTKNGVIGGIMLGLGRALGETMAVTFIIGNTYQLDSASLYMPGNSITSALANEFA
                     EAESGLHVAALMELGLILFVITFIVLAASKFMIMRLAKNEGAR"
     gene            complement(22666..23706)
                     /gene="pstS"
                     /locus_tag="OPV72_000968"
     CDS             complement(22666..23706)
                     /gene="pstS"
                     /locus_tag="OPV72_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HCR9913336.1"
                     /translation="MKVMRTTVATVVAATLSMSAFSAFAAASLTGAGATFPAPVYAKW
                     ADTYQKETGNKVNYQGIGSSGGVKQITANTVDFGASDAPLSDEKLNQEGLFQFPTVIG
                     GVVLAVNIPGLKSGELVLDGKTLGDIYLGKIKKWDDEAITKLNPGVKLPSQNIAVVRR
                     ADGSGTSFVFTSYLAKVNDEWKSKVGAGSTVNWPTGLGGKGNDGIAAFVQRLPGAIGY
                     VEYAYAKQNNLAYTKLVSADGKPVSPTEESFSNAAKGADWSKTFAQDLTNQKGDDVWP
                     ITSTTFILVHKAQKKPEQGAEVLKFFDWAYKNGAKQANDLDYASLPDNVVDQVRTAWK
                     TSIKDSNGKALY"
     gene            complement(23872..25245)
                     /locus_tag="OPV72_000969"
     CDS             complement(23872..25245)
                     /locus_tag="OPV72_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCR9913337.1"
                     /translation="MTKKIVAVTACPTGVAHAFMAAEALEIEARKRGDWIKVETRGSV
                     GAKNTLTAEEIAQADVVIIAADIELDLSGFVGKRLYRTSTGAALKKSAQEMDNAFNSA
                     EVYQGSAGRSSSAGKTELPGVYKHLMTGVSHMLPLVVAGGLCIALSFVFGIQAFNEPG
                     TLAAALFQIGGKAAFALMVPVLAGFIAFSIADRPGLAPGLIGGMLASLCGAGFLGGIV
                     AGFLAGYSVRFLAQNIKLPASMEALKPVLVLPLLSTLITGLIMIYVVGGPVSAVMEGL
                     TTFLGNMTSTNAILLGMLLGAMQGFDLGGPVNKAAYTFGVGLLASHSYMPMAAIMAAG
                     MVPALGMGVATWAARAKFTASEHEAGNASFILGLCFISEGAIPFAARDPMRVIPSTMV
                     GGAIAGGLSMYFGCTLMAPHGGLFVLAIPHAVEHVMQYLLSIALGTIVCGLMYALLKP
                     SAVAQTV"
     gene            complement(25294..26064)
                     /locus_tag="OPV72_000970"
     CDS             complement(25294..26064)
                     /locus_tag="OPV72_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate 5-dehydrogenase"
                     /protein_id="HCR9913338.1"
                     /translation="MTKRINKDTQVCMSLAARPSNFGTRFHNYLYEALDLNYLYKAFS
                     PTDLTQAISGVRGLGIRGCAISMPFKEACIPLVDELDASAKAYNTDYIAIARLLANYK
                     VSPDQVFALRGSGGMAKAVACALKDAGFTRGYIVAIDEASGKQLAELYGYEWRPDTDG
                     IEADLLINATPIGMAGGNDADKLSYSEQEVDKASVIFDVVALPPVTPLIRYARERGKT
                     VIIGSEVFAIQAVEQFVLYTGIRPDDALFQKAAAWSRL"
     gene            26159..27916
                     /locus_tag="OPV72_000971"
     CDS             26159..27916
                     /locus_tag="OPV72_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SgrR family transcriptional regulator"
                     /protein_id="HCR9913339.1"
                     /translation="MATRHTEQKYLKLLQHYGDKPVSVTLQELADVLFCTRRHMRNLL
                     LQMQEAKWLIWQSQAGRGHRARLHLRYKPEQLLSEKAEQLLESGHVDQAIQLLGKNKH
                     QVAQLLRSKLGYSVRADYQRLCIPYYRTMPSLCPGIPLRRSEQHLVRQIFSGLTRINE
                     EKGEVEADLAHHWRQIDPLRWRFYLRPAVLWHDGQELTIDAVIASLTRSAKLPLFSHL
                     QTIQATGPLSLEITLAHPDNRLPLLLSHIDAMILPPDHTQRADFPAHPVGTGPYEVVE
                     NNGFHLQMKAFDHYFGLRGLLDEVEVFIWPNLTETDNLAESLSDNDTAAWLSSSLSDE
                     DYVSGRLSQVSGKPSDNLREMFLERGGYFLLCDSRSPHWHTAEHRRWLRETLSPYALL
                     QHLSEAIRPFWVPGGSLLSSWFHTIEAGPACSPFISSSPYAKLRLAYHDQHPEFPMLL
                     DIMQEIMRQQGILLEGVELNYDDWANGKTNVDLWLGTVNFPIPEEWNVGTWLLGSPLL
                     RHAISGGDDALLAQWETQWHAETISAEQLVRETTRSGWLQPLFHHWMRLKSPDRARGI
                     HLNNLGWFDFRSTWIEPGP"
     gene            complement(27947..29014)
                     /gene="stgD"
                     /locus_tag="OPV72_000972"
     CDS             complement(27947..29014)
                     /gene="stgD"
                     /locus_tag="OPV72_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001241930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein StgD"
                     /protein_id="HCR9913340.1"
                     /translation="MRLWTIILFSCFMVLISPVCRAGDGICHAVKGTYIYNLNLNDAR
                     IPAEKNKAGTEVRDLETLTSSESYKVGCSCLTHFSSTFREVYYTARSPLSIDTTRNGY
                     TYYTLNDNLSIATSIAVLGRGFIAVPFEAEPNVVKDGMNCYTDTVEGNLATLYTGSEV
                     KVSFLINKPFVGQVAIPGTIVANLYGGLDASSSTASTDKLAEVRIVGDIVAPQSCEID
                     SGQVIEVNFGKIPVADFSTTQGTAAAGHKVTKTVQVKCTGMLDENIVYSTFNADPVDS
                     SANMMKVLGNDDVGIMIYDKWDRMVKVTGGKMDMDMGVNNGGAETNSLTFSAAPASAT
                     GARPQPGTFEAYATITLEITN"
     gene            complement(29026..31560)
                     /locus_tag="OPV72_000973"
                     /pseudo
     CDS             complement(29026..31560)
                     /locus_tag="OPV72_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258936.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
     gene            complement(31582..32280)
                     /locus_tag="OPV72_000974"
     CDS             complement(31582..32280)
                     /locus_tag="OPV72_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010989263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone"
                     /protein_id="HCR9913341.1"
                     /translation="MSLSMFARGIKIVILALLCLNLPSAFAGIVVGGTRVIFHGNDPD
                     STISIYNKEVDLPYLIQVWVDPFSKDDKSKPPFTVIPPVSRLEPSQEKVLRIIKTAGE
                     LPKDRESVFWFNVKNIPPSSKNKDSSTLEIAIKTRIKLFWRPASITLIPEKAVAKVKW
                     YRQGSKLVVENNSPIHMNIMDVSVDGKDVPLNMIKPFEKLTLDLPTGVTGHALAWRFI
                     NDYGAISSPVKQAL"
     gene            complement(32378..32926)
                     /locus_tag="OPV72_000975"
     CDS             complement(32378..32926)
                     /locus_tag="OPV72_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HCR9913342.1"
                     /translation="MVLSSTMLVGNAMASDGTVHFLGEVVDSTCQVTPQTADQNVNLG
                     KVNKTAFAGVGSTAAPTEFHIDLTGCPATYTKAAVRFDGTEASNSDGDLAIGNPANGD
                     APGDYTGDGAAITASGVAIRIYNRADNSQVKLYNDSAYSTIDTTAGTASMEFIARYIA
                     TDATVTAGTANADSQFTVEYQK"
BASE COUNT         7738 a         9108 c         8568 g         7516 t
ORIGIN      
        1 gatattattg atgttgctaa tgattttgcg tccgccacca gcaaatggcg tccggtggtg
       61 gtaaaaatta ataccgacga gggcatttcc ggttttggcg aagtcgggtt ggcctacggc
      121 gtcggcgcct ccgcaggcat cggcatggca aaagatttag ccgccattat catcggcatg
      181 gacccgatga ataacgaagc catctgggaa aagatgctca aaaagacgtt ctggggacaa
      241 ggcggcggcg gcatcttttc cgcagcaatg agcggtatcg atatcgcgct gtgggatatc
      301 aaaggcaaag cgtggggcgt gccgctgtat aaaatgcttg gcggcaaaag ccgcgagaaa
      361 atcagaacct acgccagtca gttacagttt ggttgggggg acggcagcga taaagatatg
      421 ctgaccgagc cggagcagta tgcacaggcg gcgctgaccg ccgtcagcga aggctatgac
      481 gcgataaaag tggataccgt cgcaatggat cgccacggca actggaacca gcaaaacctc
      541 aacgggcctc tcaccgataa aatcctgcgt ctgggctacg accgtatggc cgccattcgc
      601 gatgcagtcg gcccggacgt ggatatcatc gccgaaatgc atgcctttac ggataccacc
      661 tcggcgattc agtttggccg catgatagaa gagctgggca tcttctacta cgaggaaccg
      721 gtcatgccgt taaaccccgg acaaatgaaa caagtggctg ataaaattaa tattccactg
      781 gcggctggcg aacgcattta ctggcgctgg ggataccgtc ctttcctgga aaacggcagc
      841 ctgagcgtga tccagcccga tatttgtacc tgcggcggca tcaccgaagt gaagaaaatc
      901 tgcgatatgg cgcatgttta tgacaaaacg gtgcaaatcc acgtttgcgg cgggccgatt
      961 tccacagcag tggcgctgca tatggaaacc gcaatcccta acttcgtcat ccacgaactg
     1021 caccggtatg cgctgctgga gccgaataca cagacctgta aatacaacta cctgccgaag
     1081 aacggcatgt acgaagtctc ggagcttccc ggcatcggcc aggaactgac cgaagaaacc
     1141 atgaaaaaat caccaaccat caccgtaaaa taagccaact gtctgcctgc gccgcaggca
     1201 gacaccctgt atttgcgagt cgtatcaacg cgaccttatc cagcctgaga taaaatcctc
     1261 tcagtaaagg ggtaacacag gtggcaaatg aatttaacta tccggcaatt tcgcgcgttt
     1321 ctggccgtcg cggatttgcg tagttttacc gccgccagca aatatctgtg catcacgcag
     1381 ggagctgtta gcggtttaat caacgaaatg gaaagccaga tggaggtttc ccttttcgac
     1441 cgcacttcgc gcgtggtgaa gctatcgccc gacggcgaaa agtttttacc cgccgccatg
     1501 cgggttgttg aagagtttca acgggccgaa aattatgccc gcgacctgaa agagatcaaa
     1561 aaatccctgg tgcgggtggt cggcgcgccg ctgatcgcct gtgcttttct gccgcaaatc
     1621 atccatgcct ttaagcggca gcatccgcat acccacgtac agcttattga taagcccatg
     1681 tcgcaattac aaaaaagcat tatgttggga gaagccgatt ttggtatcgg cccggagcgg
     1741 ccgctggaac cggaaatcga caaacaaacg ctgttcacaa cggaaatcgc cctgtactgc
     1801 catccggact atcggctgca taaaaaaacg gtgcgctggg aagagattca gagcgaagag
     1861 ctgatcgccg ttggcaacga atccgttccg atgatctccg cgaccgctgg cgtgcgcatt
     1921 aagcccaaaa tgacggtgga acatatggcg accgccatgt cgctggcggc gcagtgtgaa
     1981 ggcgtggtga tcgccgaaac cttttcccgc cattacgcca aaagctatca attagcgacc
     2041 tgttcgctca cgcctccgct gcggcgcaat atgaaccttt atttccatgc gtggcgcgcg
     2101 caaacgcccg ccacgcagcg ctttaaagag tttctattca gatatatgga tgaacatcat
     2161 gatgccctgg ccagccagcg gcgggccggg gattaaggca ggttaaatat cgatgttcgc
     2221 cgctttcagg gcgttctcct cgataaaggc acgacgcggc tcaacggcat cacccatcag
     2281 cgtagtgaac agctggtcgg cagcaattgc atctttgacg gtcacgcgca gcatacggcg
     2341 gctttccggg tccatggtgg tttcccacag ctgatccggg ttcatttcac ccagaccttt
     2401 ataacgctgg atagccagac cgcgacgtga ttctttcacc agccactcca gcgcctgctc
     2461 gaagctggtt accggctggc gacgctcgcc gcgttcgatg aacgcgtcct cttcaatcag
     2521 accgcgcagc ttctcgccca gcgtgcagat acgacgatat tccgcgccgg tcacaaactc
     2581 gtgatccaac ggataatcgg tatccacgcc atgcgtacgc acgcgaacga tcggctcgaa
     2641 cagattctgt tccgtattag tatgaacatc gaacttccac tgactgccgt gctgctcttt
     2701 ctcattcagc tcggtaatca gcgcattcac ccaacgcgtt acagtctgct catcagaaag
     2761 atcggcttcg gtcagagttg gctgatacac cagctctttg agcagcgctt tcgggaagcg
     2821 acgctccata cgaccaatca ttttctgcgt ggcgttatat tcagagacca gtttttctaa
     2881 cgcttcgccg gatagcgctg gcgcatgagc gttcgcgtgc agagtcgcac cgtcaagcgc
     2941 gatggaaatc tggtactgat ccatcgcttc gtcgtctttg atgtactgtt cctgcttgcc
     3001 tttcttcact ttgtacagcg gcggctgggc aatgtaaacg tggccgcgct cgacgatttc
     3061 cggcatctga cgatagaaga aggtcaacag cagcgtacgg atgtgcgagc cgtcgacgtc
     3121 cgcatcggtc atgatgatga tgctgtgata gcgcagcttg tccgggttgt actcgtcgcg
     3181 accgataccg cagcccagcg cggtgatcag cgtcgccact tcctgggagg aaagcatctt
     3241 gtcgaagcgc gctttctcga cgttaaggat tttacctttc agcggcagaa tcgcctggtt
     3301 cttgcggtta cgcccctgct tcgcagagcc gcccgcggag tccccttcca ccaggtacag
     3361 ttcggacagc gccgggtcgc gttcctgaca atccgccagt ttgcccggca gaccggctaa
     3421 atccagcgcg cctttacgac gggtcatttc acgggcgcga cgcgccgctt cacgcgcacg
     3481 cgcggcgtcg ataattttgc cgacgacgat tttcgcgtca gatgggtttt ccagcaggta
     3541 ttcgctcagc agttcgttca tctgctgttc taccgccgat ttcacctcgg aagagaccag
     3601 cttatctttg gtctgtgagg agaatttcgg gtccggcact tttacggaaa ccaccgcaat
     3661 cagaccttca cgggcatcgt cgccggtggc gctgactttg gcttttttgc tgtagccttc
     3721 tttgtccatg taggcgttca gcgtgcgggt catcgccgca cggaagcctg ccaggtgagt
     3781 accgccgtcg cgctgcggaa tgttgttggt aaagcagtag atgttttcct ggaaaccatc
     3841 gttccactgc agcgctactt ccacgccgat accgtctttt tcggtggaga aatagaagat
     3901 attcgggtgg atcggcgttt tattcttgtt gagatattca acaaacgcct tgatgccgcc
     3961 ttcgtagtgg aaatgatctt ctttgccatc gcgcttgtcg cgcaggcgga tggaaacgcc
     4021 tgagttcagg aatgacagtt cacgcaggcg tttcgccagg atctcatatt caaattcagt
     4081 gacgttagtg aaggtttcgt ggctcggcca gaaacgtacc atcgtgccgg ttttatcggt
     4141 atcgccagtg acggccaggg gtgcctgcgg cacgccgtgc tcgtagatct gacggtgaat
     4201 tttgccatct cgctggataa ccagctccag tttttgcgac agagcgttga ctaccgagac
     4261 gcccaccccg tgcagaccac cggagacttt ataggagtta tcgtcaaatt taccgcccgc
     4321 gtgcagaacg gtcatgatca cttccgccgc cgagacgcct tcttccggat gaatcccggt
     4381 cggaatgcca cggccatcat ccgttacgga cacggagtta tcggcgtgaa tagtcacgac
     4441 gatatcttta cagtgacccg cgagcgcttc gtcgatagcg ttatctacca cctcgaatac
     4501 catgtggtgc agaccggtgc cgtcatccgt gtcgccgata tacatacccg ggcgcttacg
     4561 caccgcatcc agccctttca ggactttgat actggaggag tcataagaat tcgacatcaa
     4621 cgtttctcgc tcatttaatc ttgggttaat ccgttatttt acccttttcc acggtaaaca
     4681 tcttcgaatt ttcatccgac atgtctataa cgtgttcagc gctaattgcg ctgacaaaga
     4741 cctgcgattg cgtggctttt aagcggctgg ccagcagtcc gcgacgcgca tcgtcaagtt
     4801 cagaggcaaa atcatctatc aggtacaggc agcgccgccc gctttcgcgg gtaaggaact
     4861 cgccctgcgc cagacgtaag gcgcacatca acaactttag ctgaccgcgc gacagggtat
     4921 cttccaccgg cgcgccgtca gcgcgaatgc gaaagtccgc tttatgcggc ccgtgcgcgg
     4981 tgtaggtcaa catacggtca cgctcaaagc ttcgctccag cacgtccgca tagtctgtct
     5041 ctttctccca gccgcgctgg aaagagaacg tcagggaaaa ttcaggtaaa aactgctgac
     5101 aggtatccgc catgtcctgt gcgatagcgc tactgtactc cgcccgccag gtactaattt
     5161 gttccgccaa cggaatcagc tctttatccc acgggcgcaa ttgctcataa cggctcacct
     5221 ggcgcagcgc ggcgttacgc tgtttcagca atcgtttcag gttgctccaa gcggtgaaga
     5281 atccggcttc gttgtgaaag catccccagt caaggaacgc tcttctgtat ttggggccgc
     5341 cgttgagtaa agtaaacccc tccggcgtaa tcaactgcat cggcattaaa tgcgccagct
     5401 ccgcgatctt gtgaccgtcg gtaccgtcga tacggacttt gctgtcgccc tgcttatctt
     5461 tggttaagcc aatcgacgtc tcacgctctt cgccctgcag gcgcccgtga agaacaaacg
     5521 cttcctgctc atgacgaatc acgcggccag gctgcaaact gcgaaacgcc cgaccgtggc
     5581 caagcgtata aatagcttcc agcacgctgg ttttgccgct accgttggcg ccaaccagga
     5641 aattaaagcc gggggataaa gcgagatccg cattttctat gttgcggaag tctttgatta
     5701 gcagtctgga tagcgacata tcaactcata accagggcgt tatcggcgca gttagtctgg
     5761 ttacggccag cgcacagcaa ccggagcgta ctggagtacg tgaggattgc tcgctgcgct
     5821 cgcccttcgg gccgtccata agacgtccaa aatacttcgt attttgtgcg agcactgccc
     5881 ggagccagaa taacaagtaa gatagcccga tattctttac aagcgcattg gcataacaac
     5941 ataggcagcc gactgtgacg ccgcatcctc aatctgtacg ctggatacgg aatccgtcag
     6001 cataatgcgc acggtttcgc acttcagcgc attgagcacg tccagcacgt aactgacgtt
     6061 aaagccgatt tccatctccg tcccgccata gctcacgtcc agaatctctt ccgcttcttc
     6121 ctgttccggg ttattggcgg tgattttgag ctgattctca ctgacgtaca gacgcacgcc
     6181 gcggaatttc tcattcgaga ggattgctgc gcgggcaaac gcctgcttga ggatatcgca
     6241 gcccgcttcc agatgtttat ccggattctt cggcaatacg cgacggtaat ccgggaaacg
     6301 accatccacc agcttcgagg taaagataaa gtcgccgacg tgcgcgcgga tattattact
     6361 gccgatctgc acgcgcagcg ggttttcgcc accgtcgagc atacgcatca gttcaatcac
     6421 gcctttacgc ggcacaatca ccgagtggct aggtaaagac gcctccagcg gcattgagca
     6481 caccgccaga cggtggccgt cggtcgcaac agtgcgcagt tcgctacctt ccgtttcaaa
     6541 cagcataccg tttaagtagt agcgcacatc ctgatgggcc atcgaaaact gggtcgcttc
     6601 aatcaggcgc ttcatcgtgg cctgcggcag cgtaaattca acttcgcttt gccagtcgtc
     6661 aagattcggg aaatcggcgg caggcagcgt agacagcgag aagcggctac ggccagaacg
     6721 caccagcatc cgatcgcctt ccaactgaac ggcaatctcc gcgccctccg gcaggccgcg
     6781 gcagatatca aagaatttcc gcgccggcac ggtagtggcg cctggctcat gcggctgaga
     6841 aagcgtaacg cgcgcgacca tctccatttc aagatcggtg ccggtcagag aaagcgtacc
     6901 gtccgctacc tggaggagca ggttaccgag aatcggcagc gtaggacgac cgcccagcgg
     6961 gccgctgacc tgctgaagcg gttttaataa atgttcacgt tcaacggtaa atttcatagg
     7021 atcacgacga caatgttctg attaaattcg aaaaatcttc tttgatatcg tggctttctt
     7081 cacgcagttg ctcaatttta cgacaggcat gaagtacggt agtgtggtcg cgcccgccaa
     7141 acgcatcgcc gatttccggc agactgtggt tggtgagctc ttttgccagc gccatagcca
     7201 tctggcgcgg acgtgctacc gagcgagatc gacgcttaga aagcagatcc gcaattttga
     7261 ttttgtaata ctcggccacc gtcttctgaa tattgtcgat ggtgaccagt ttttcctgca
     7321 acgccagtaa atcgcgcagc gcttcgcgca caaagtcgat agtaatcgcc cggccggtaa
     7381 agttggcatt ggcgatcacc cggttcagcg cgccttccag ttcacgtacg ttagagcgta
     7441 gacgcttggc gataaagaac gctacttcgc ctggcagacg aatatcattt tcgtccgctt
     7501 ttttcatcag gatcgccacg cgggtttcca gctctggtgg ttcgatcgcc actgtcagcc
     7561 cccaaccaaa gcgggacttg agacgatcct caacgccgtt gatctctttc ggatagcgat
     7621 ccgacgtcaa aatgatctgc tgattgcctt ccagcagagc gttaaaggtg tggaaaaact
     7681 cttcctggga tcgttcttta ttggcgaaga attgaatatc gtcgatcagc aatgcgtcaa
     7741 cggagcggta gtagcgttta aactcttcga tggcgttatt ttgcagggct tttaccatgt
     7801 cctgcacaaa gcgctcggag tgcatataca cgactttcgc gttgggtttg cgcgccataa
     7861 tgccgttacc caccgcgtgc agcaggtgag ttttacccag accggtgccg ccatagagga
     7921 ataacgggtt ataggcgccg ccaggattat ccgccacctg acgtgccgcc gcgcgcgcca
     7981 gttggttgga tttaccttcg acgaagttat caaatgtatg cttaacattg acgttggagc
     8041 ggtaggtcgg ctccgccggc gctggtacgt tatcccagcc cgaacgggcc gcgggcgcta
     8101 cgcgctgcgg ttgcgccgtc gttgtctgcg taggcgcgac aacgttatgc acaggcgttt
     8161 ttagcgtttg cgtaacgggc tttgttccca cttcaaaacg cagttgtggg gcatccgcgc
     8221 cgcagaatgt gttgagtaat ccattgatat tgttgaggta cttatctctt acccaatcga
     8281 gcacaaaacg gtttggcgca tacaaagcca gcgtgttatc gctcagttcc gcctgcaacg
     8341 ggcgtatcca catactgaat tctgtggctg gtaactcatc ctgcaatcgg gcaagacact
     8401 gctgccaaag cgaaagtgac acggcggact ccactcgaac aaaagtcgat aaatgacaaa
     8461 ggctgataca ttaatgattg ttggcgcacg tcgataagac cctgcatgaa gggtgacgca
     8521 ctaaccgctg tctgcggttt tcacggatct ttcaaacgat cgcgacttca cgcagtctga
     8581 aagatttcgt gttcatgcct gaccaggatc gtttgaaacg atcaggaccg cggatcatag
     8641 cctaaactga gcaagagatc ttctgtttct cacagattct tcccgattta tccacagggc
     8701 tttccaggaa aggataagtg taatcgatcc aggggaactc ctgtacgctt tcgcgcgcat
     8761 attgaaaaaa ttaatatgta aaggtgagca gacgcctaaa agatcgcata aagatccagg
     8821 gcgatccttg cgctttacct ggcagtccgt ataattctcc acccgtcgcg caatgcccgt
     8881 catatggcgt caacgctgct tattttccgc acaaaaaggc gtggaaaatc gcgggaaagt
     8941 aaggaaagag aattgactcc ggagtgtaca attattacaa tccggcctct ttaatcaccc
     9001 acactgtggc gtaagtcgtt caaagtttgt tcgggtatac gcaaaagtca gtgaatttat
     9061 tcaagtttag gtagaaatcg ccatgaaacg cacttttcaa ccgtctgtac tgaagcgcaa
     9121 ccgttctcac ggcttccgtg ctcgtatggc tactaaaaat ggtcgtcagg ttctggcacg
     9181 tcgtcgtgct aaaggccgcg ctcgtctgac cgtttccaag taataaagct aacccctgag
     9241 tggttaagct cgcatttccc agggagttac gtttgttaac tcccgctcat ttcacattcg
     9301 tcttccagca acctcaacgg gctggcacgc cgcaaatcac catcctcggc cgcctgaatt
     9361 cgctggggca tccccgtatc ggtcttaccg tcgccaagaa aaatgttcga cgtgcgcatg
     9421 aacgcaaccg gattaaacgt ctgacgcgtg aaagcttccg tctgcgccag catgaacttc
     9481 ctgcaatgga tttcgtggtg gtggcgaaaa aaggggttgc cgacctcgat aaccgtgctc
     9541 tctcggaagc gttggaaaaa ttatggcgcc gccactgtcg cctggctcgc gggtcctgat
     9601 agcccttatt cgggtctatc aacgcctgat cagtccgctg cttgggccgc attgtcgttt
     9661 cacgccaacg tgctcaagct acggaattga ggcattgcgc aggtttggag tgataaaagg
     9721 cagttggttg acggtgaaac gcgtattaaa atgccaccct ttacaccctg gtggtgacga
     9781 tcccgtcccg cccggaccat ttgataccag agaacactaa cgatggattc gcaacgcaat
     9841 cttttagtca tcgctttgct gttcgtgtct ttcatgatct ggcaagcctg ggagcaggat
     9901 aaaaatccgc aacctcagac tcaacagacc atgcagacaa cgaccaccgc agcgggtagc
     9961 gccgccgacc agggcgtacc agccagtggc caggggaaaa tgattacggt gaaaaccgat
    10021 gtgcttgatt tgactatcaa cacccgtggt ggtgatgtcg agcaggcctt gctcccggct
    10081 tacccgaaag aactgggttc caacgaaccg ttccagctgc tggaaaccac cccgcagttt
    10141 atctatcagg cgcaaagcgg cctgacaggc cgcgacggcc cggataaccc ggcgaacggc
    10201 ccgcgtccgc tgtacaacgt cgagaaagat gcgtttgtac tggccgacgg tcagaacgaa
    10261 ctgcaggttc cgatgactta tactgacgcc gcaggcaaca cgtttaccaa aacgtttgtc
    10321 tttaagcgtg gcgattatgc ggttaacgtg aactatagcg tgcagaacac cggcgaaaaa
    10381 ccgctggaag tctccacctt tggtcagtta aaacaatccg tcaacctgcc tcctcatcgc
    10441 gacaccggca gtagcaactt tgcgttgcat acgttccgcg gcgcagcgta ctccacgccg
    10501 gatgagaagt atgagaaata caaattcgac accattgccg ataacgaaaa cctcaacgtc
    10561 agctccaaag gcggttgggt ggcaatgttg cagcagtatt tcgctaccgc atggattccg
    10621 cgtaacgacg gcaccaacaa tttctacacc gccaatctgg gtaacggcat tgtcgctatc
    10681 ggctataaag cgcagccggt actggtacag ccaggccaga ctggcgcgat gaccagcacc
    10741 ctgtgggtcg gcccggaaat tcaggataaa atggcggctg ttgcaccgca cctggatttg
    10801 accgtggact acggctggtt gtggttcatc tctcagccgc tgttcaagtt gctgaagtgg
    10861 atccacagct ttgtgggcaa ctggggcttc tccattatca tcattacctt tatcgttcgc
    10921 ggtatcatgt acccgctgac caaagcgcag tacacgtcaa tggcgaagat gcgtatgctg
    10981 cagccgaaaa ttcaggcgat gcgcgaacgt cttggcgatg ataaacagcg ccaaagccag
    11041 gagatgatgg ccctgtacaa agcggagaag gttaacccgc tgggcggctg cttcccgctg
    11101 atcatccaga tgcctatctt cctggcgttg tactacatgc tgatgggttc cattgaactg
    11161 cgtcatgcgc cgttcgcgct gtggattcat gacctgtctg cacaggaccc gtactacatt
    11221 ctgccgatcc tgatgggcgt aacgatgttc ttcattcaga agatgtcgcc gaccaccgtg
    11281 accgacccga tgcagcagaa gatcatgacc tttatgccgg tcatctttac agtgttcttc
    11341 ctgtggttcc cgtcaggtct ggtgctgtac tatatcgtca gcaacctggt caccatcatt
    11401 cagcagcagc tgatttaccg tggtctggag aagcgtggcc tgcatagccg cgagaagaaa
    11461 aaatcctgat tcggtgtagg ccggataagg cgaagccgcc atccggcaag gcgcgccggt
    11521 cagcctgatg gcgctaacgc ttatcaggcc tacaatcaaa aggcggtcat atgaccgcct
    11581 ttttttattg caacaaagtt gagactaacc atgagccata acgacactat cgtcgcccag
    11641 gcaaccccac cgggacgcgg tggcgtgggt atcctgcgta tttccggtct gaaggcgcgc
    11701 gacgttgcgc aagaggtgct gggcaagctg ccgaagccgc gctatgccga ctacctgccg
    11761 tttaaagatg ttgacggcag cgcgctggat cagggtattg cgctgtggtt ccccggcccg
    11821 aactccttca ccggtgaaga tgtgctggag ctacaagggc acggcggtcc ggtgattctg
    11881 gacctgctgt taaaacgtat cctgacgctt ccaggcgtgc gaattgcccg accgggcgag
    11941 ttctccgagc gagcgttcct caacgataag ctcgatttag cccaggcgga agccattgcc
    12001 gacctgatcg atgccagttc cgaacaggcg gcgcgttcgg cgctaaactc gttacagggg
    12061 gcattttccg cccgcgttaa ccaccttgtg gaagcactta ctcacctgcg aatctacgtc
    12121 gaagcggcta ttgattttcc ggatgaggag atcgactttc tctctgacgg caaaatcgaa
    12181 gcgcagctca atggcgtcat cgccgatctt gacgccgtgc gcaccgaagc gcgccagggc
    12241 agcctgctgc gcgaagggat gaaggtagtg attgccggac gcccgaatgc cgggaaatcc
    12301 agcctgctga atgcgctggc aggccgtgaa gcggccattg tcaccgatat cgccggtacc
    12361 acgcgcgacg tgttgcgcga gcacatccac atcgacggga tgccgctgca tatcatcgat
    12421 accgccggac tgcgcgacgc caacgacgaa gttgagcgta tcggcatcga acgcgcctgg
    12481 caggagattg aacaggccga tcgagtgctg tttatggtgg atggcaccac gacggacgcc
    12541 gttgaccctg ccgacatctg gccggacttt atcgcccgtc tgcccaaaaa tctaccgatt
    12601 accgtggtac gtaacaaggc ggatatcacc ggcgaaacgc tgggtattag tgaagtaaac
    12661 ggtcactcac tggttcgcct ctcggcgcgt accggcgaag gcgtcgacgt gttgcgtaac
    12721 cacctcaagc agagcatggg gtttgatacc aatatggaag gcggcttcct ggcccgccgc
    12781 cgtcacctgc aggcgctggc ggaagccgct aaccatcttg aacagggcaa agcgcagcta
    12841 ttaggcgcat gggcggggga actgctggcg gaagagttgc gcctggcgca gcaaagctta
    12901 agcgagatta ccggcgagtt tacctccgac gacctgctgg gacggatttt ctccagcttc
    12961 tgtatcggta aataacgttg tgttgcccgg tggcgcgatg cttaccgggc ctacaaaacc
    13021 cgtaagccgg ataaggcgtt tacgccgcca tccggcagca atgatttccc atgcggaaat
    13081 cactgttgtc caaatgacaa ctcgtctcgc gcaacgtcgc cccgtattct tagcgccaca
    13141 cttttcgtga ggccgctatg aaacgttttc tactgtgtag ttttgccctg gttttactct
    13201 atcctgctgg tattgatatg tatctggtcg gtttaccgcg tatagccgcc gatctgaacg
    13261 ccagcgaggc gcagttgcat atcgccttct ccgtttacct ggccggaatg gcgacggcca
    13321 tgctgtttgc cgggaagata gccgaccagt caggccgcaa gccggtcgcg atcgtcggcg
    13381 cgatcgtctt tatgatggcc tcactgcttt gttcacgggc gtcggaaggc tcgctatttc
    13441 tgagtgggcg ttttcttcag ggggtaggag caggcggctg ctatgtggtg gcgttcgcca
    13501 ttctgcgcga cacgctcgac gagcatcgcc gggcgaaagt gctgtcatta ttgaatggga
    13561 ttacctgtat tgtgccggta ctcgccccgg tgatggggca tttgattatg cttcgtttcc
    13621 cctggcaaag tctgttctat acgatgtcca cgatgggcat tatggtgggc ctgttatcac
    13681 tgtttatcct gcgcgagacg cgcccggcaa ggctggctcc acgcgattta tcaccatcgt
    13741 cgtccgccgc cgagtcgctg gttaaccgtt ttttcgttag tcgactagcg atcaccaccc
    13801 ttagcgtgtc ggtgatcctg accttcgtca atgcctctcc agtgctgctg atggaggtga
    13861 tgggatttag ccgtggcgac tatgccatta ccatggcgct caccgcaggc gtcagcatgg
    13921 tcgtctcttt ttctacccct tttgcgcttg ggttatttaa gccgcgaacc ttaatgctcg
    13981 tctcacaggg gctgtttttg acggctggcg tgacgttaag ccttgctcat accaataccg
    14041 tcacgctctt tggcctgacg cttatctgcg ccggattctc ggttggtttt ggcgtcgcga
    14101 tgagccaggc gctggggccg ttttcgctgc gcgccggagt ggccagttcc acgctgggta
    14161 tcgctcaggt ttgcggttca tcactgtgga tttggctggc ggcaatactc ggtatcagcg
    14221 cgatgaatat gctgatcggg attctgattg gttgtagcat agtgagtatt ctgctgatct
    14281 tctccgtcgc gcccaacagg tccgtagccg agcatgaaga aatcccttac cagtctcgat
    14341 cttaatctgc tgttatgcct acagttactc atgcaggagc gcagcgtcac taaagctgca
    14401 aaacggatga acgtaacgcc ctctgcggtc agcaaatcgc tggcgaaact ccgggcatgg
    14461 tttgacgatc cgctgttcgt caatacgccg ctgggcctgg cgccgacgcc gctgatggtc
    14521 agtatggagc aaagtctggc ggactggatg cagatgggga atcaactgct tgataagcca
    14581 catcatcaaa cgccgcgcgg tttaaaattt gagttggcgg cagagtcgcc gctgatgatg
    14641 attatgttta attcactgtc gcagcagatt tatcagcgct atccgcaggc taccattaag
    14701 gttcgcaact gggattatga ctcgctggag gcgattacgc gcgggaaagt cgatatcgga
    14761 tttaccggac gcgaaagcca tccccgctcg cgagagttga tcagtctgtt gccgctcgcg
    14821 attgactttg aggtactgtt tagcgattta ccgtgggtct ggctgcagga agatcatccg
    14881 gcactgcgcg aagcgtggga tctggacact tttctgcgct acccgcatat cagtatttgc
    14941 tgggagcaaa gcgatacctg ggcgctggat gatgtcctac aagaaatggg acgcaaacgc
    15001 catatcgcgt taagcctgcc ggggttcgag cagtcgctct ttatggccgc ccagccgggt
    15061 cacaccctga tagcaaccgc gccgcgctat tgccagcact acaatcagct ccaccagcta
    15121 ccgttagtgg cgcgccccct gccttttgat gcgcaacagc gggaaaagct gatggtgccg
    15181 tttaccctat tatggcacaa acgtaatagt cataatccca agattgtgtg gctacgacag
    15241 gctatcaaca cgctctgccg tcgccttatc tgaccacctg cgttgataaa ttaaccttac
    15301 tcttaccaga aatgtcaccg tctgattaaa gaaccttctg aaattgaatt tttagcgcgt
    15361 aaaacctgtc cataatttac gttaatgtta ctctcgtcat tatcacggcc cattaatcac
    15421 ggagcgaaaa atggcgactc actttgccag agggatactt acggagggac agttggtttc
    15481 aattcgtctc tcttcgtctt gccatattga agccagaaac ctgcctgctc accgacgaac
    15541 gcgttttctc gcctccagag gccttcttgc cgaactgatg tttatgctgt acggaattag
    15601 cgagctgccg gaaatcatta ttcaggcgaa aggtaaaccc gcgtttcgtg acaaaaatct
    15661 gccaggtttt tctatctcct acgccggaaa tatggttggc gtggcgttga ccaccgaagg
    15721 agagtgcggg ctggatatgg aattacagcg cacctcccgc ggctttcacc atccgcattc
    15781 gctcgaacgc caccctttct cccgtaatga aaacttatgg gtagccaatc aaaacgatcc
    15841 caacgaagcg cgagcgcaac tcattacatt gcgccagagc gtgttaaaac tcaccggcga
    15901 tgtcatgaat gacgatccgc gggagctgca acttttaccc gttgccggac gcctgaagtg
    15961 cgcgcatgtc acgcagcttg aagccgtgtg cgatgcggaa gatgtgctgg tatggtccgt
    16021 aaccgttacg ccagcgatag aaaaattaaa agtgtgggag ttcgatggca aactgggctg
    16081 gaaaagcctg cccgatatcc agacgcgcgc caatgagcca accggccgtc tgatgcgatt
    16141 cgcccaactc cccgccgcca aatcgtatac gcttaatcgt tcataatgaa aaaaggggca
    16201 cgtatgtctg aaatgctgaa tgtggttaca ttgctgggaa gtttacgcaa aggttccttt
    16261 aacgggatgg tggcgcgtac gctgcctaaa gtcgcgccgg caggaatgac ggtatcgccg
    16321 ctgccttcaa tcggggatat tccgctgtat gacgccgata tccagcagga agagggattt
    16381 ccagccagcg tagaggcgct ggcggagcag attcgcaacg ccgacggcgt cgtcattgtg
    16441 acgccggaat ataactattc cgttcccggc ggcctgaaaa atgccatcga ctggctatcc
    16501 cgtctgcctg agcagccgct ggcgggtaag cccgttctta tccagaccag ctcaatggga
    16561 gcgattggcg gcgcgcgctg ccagtatcat ctgcgccaga ttctggtgtt ccttgatgcg
    16621 atggtgatga ataaaccgga atttatgggc ggcgtgattc agaataaagt cgacccgcag
    16681 actggagaag tggtggatca gggaacgtta gatcatttga ccggtcagtt gaccgcattt
    16741 ggcgagtata ttcagcgcgt taaagcgtaa gttagttaaa caccctcccc ccgatggggc
    16801 gagggttcat ttcatcagtg tgcgtcaata aacacaatct tcagcacgaa taacagcgcg
    16861 acaatcacta cgcacgggct aaggtcgcgc aggcgaccgg taccgatttt catcacgcag
    16921 taagagataa agcccagcgc gataccttcg gtgatcgaga agctaaacgg catcattacc
    16981 gccgtaataa acgccgggac cgattcggtt aaatcctgcc agtttacccg cgccaggctg
    17041 gaggtcatca gcacgccgac gtaaatcaac gcgcccgccg ccgcgtaagg cggcaccatg
    17101 cccgccagcg gcgacaggaa gataaccagc aggaacaaaa taccgactac caccgccgtc
    17161 aaaccggtgc gaccgcccac cgaaacgccg gaagacgatt caatataagc ggtcacagaa
    17221 gaggttccga caaatgcgcc agtgacggaa gagatactat caacaaacag cgcctgcttc
    17281 atgcgcggga atttgccttt ctcatccgcc aggccggctt tatcggtcac gccaatcagc
    17341 gtaccggagg agtcaaacag gtttaccagc atgaaggaga aaataacccc cgccaggcca
    17401 agattgaacg agcctgccaa atcgacatgc cctaccacgc tggtgacgct tggcggcgcg
    17461 gagacaatgc cgttgtagtg cacatcgccc attatccagc caagcagcgt cgtgacgatg
    17521 atggacacca gcaccgccgc atgaatgttg cgcgaagcga gaatcgcaat aataaagaat
    17581 ccgagaaccc ccagcagcac gctgtgcgaa gtcaggttgc cgatgctgac cagcgtttcc
    17641 gggttagcga cgatcacgcc ggcgtttttc agccccatca tgccgataaa caggccgatg
    17701 ccgctggtga tgcccacgcg caggctgacc ggaatgttgg caatcatcca gtaacgcacg
    17761 cggaagatag tcagcaataa aagaccaaca gcgccccaga aaatggcgcc catgcctacc
    17821 tgccacggca gtcccattgc ctgcacaacc acgaaggcaa agaacgcatt cagccccatc
    17881 gcgggcgcca gcgccaccgg caggttagcg aacaggccca tcagaatact gccaaaggcc
    17941 gcaatcagac aggtggtcac aaagacggcg ctggtgtcca tgccagctac gcccagaatt
    18001 tgcgggttaa caaaaacgat ataaaccatc gtcaggaaag tggtaaaacc ggcgatcact
    18061 tcggttcgtg ccgtcgtgcc atgttcgcgc agtttaaaca cgcgttccag cataccctga
    18121 ccagaagcct gggtggtgtg ttgttgactc attatcaatt tccggagaaa ggagggaaaa
    18181 ttcgccgtta tcctatacca aaatgcgaca cctggcgcag ttgtgtggta atttttttca
    18241 ctcaatttgt tagtacggca acgattgcgt cccctcattc agcattacgt aaacgttaaa
    18301 cttgttaaaa tggaaatgac atgtcccaaa tcgaagcggt gttttttgac tgtgacggca
    18361 cgctggtcga cagtgaagta atttgctcgc gcgcctatgt cactatgttc cggcagttcg
    18421 gcattacgct tgagctcacg gaagtattca gacgctttaa aggcgtaaag ctctacgaaa
    18481 ttatcgatac catcagtaaa gagcatggcg ttgcgctggc aaaggcggag ctggagccgg
    18541 tgtatcgcgc ggaagtggcg cgcctgttcg ataccgaact ggaagcgatc gcgggcacaa
    18601 ataccctgct ggagagcatt aagacgccca tgtgcgtggt atccaacggg ccggtcagta
    18661 agatgcagca ttcgctgggt aaactgggca tgttgcatca ttttcccgat ttgctgttta
    18721 gcggttacga tattcaacgc tggaagcccg atccggcgct gatgctccat gcggcgaacg
    18781 ccatgaaggt caatgttgag aagtgtattc tggtggatga ttccagcgca ggcgcgcagt
    18841 caggaattgc ggcgggaatg gaagtatttt atttctgcgc cgatccgcat aacaagccga
    18901 tcgatcaccc taacgtgacg acatttaccg atttggcgca gttgccggga ttgtggaaag
    18961 cgcgcgggtg gaagattacg cgttaactga aatgccggat ggcgctaacg ctcatccggc
    19021 ctacagcatc tgtacctgta ggcccggtaa gcgcagcgcc accgggcaaa agaatgagat
    19081 ttactctttc ggatctttcc ccgccagcag cttatccagc tcatcgccgc cgacgtgacg
    19141 gaaatcctgc cccttcacga agtagaagat gtattcgcag atattctggc aacggtcacc
    19201 gatacgctcg atagaacgag cgcagaataa cgcggtcagc acgctgggaa tggtgcgcga
    19261 gtcttccatc atgtaggtca tcagctgacg cacgatacct tcgtactcct ggtcaacttt
    19321 cttgtcttca cggtagatac gcaccgcttc gtcgagatcc atgcgcgcga acgcatccag
    19381 cacgtcgtgt agcatctgca cggtgtggcg gcccagcgac tccagactca ccaacagcgg
    19441 ctggtgctgc tgggagaatt tctccagcgc ggtacggcag attttatccg ccacgtcgcc
    19501 aatgcgctcc agttcggcga tggttttgat aatcgccatc accagacgca ggtcactcgc
    19561 cgtcggctgg cgcttggcga taatacgcac gcaggcttca tcgatggcga cttccatcat
    19621 attaacctga tggtcgcctt ctaccacgcg cttcgccagc tcgctgtcct ggttgtgcat
    19681 ggcggtaata gcgtcagaaa gctgctgctc caccatgccg cccatggtca ttacctgagt
    19741 gcggatgctt tccagttcgg cgttgaactg gccggaaata tgtttattaa ggttcagact
    19801 gtccattacg cactcctgaa ttaaccgtaa cgaccggtga tataatcttc tgtttgtttc
    19861 ttcgcgggct tggtgaacag atcgtccgtg ttgctgaact caatcaactc gcccaggtac
    19921 ataaacgccg tatgatcgga acaacgtgcc gcctgctgca tgttatgggt cacgatcacc
    19981 acggtgtaat cctgtttcag ctcggtgatc agctcttcga tacgcccggt ggagatcggg
    20041 tccagagctg aacatggctc atccagcagc aacacttccg ggcgaatggc gataccgcgc
    20101 gcaatgcaca gacgctgctg ctgaccaccg gagagagagt acccgctctg gtgcaattta
    20161 tctttggttt cgttccataa tgcggctttg gtcaacgccc actgcacgcg ctcgtccata
    20221 tcggcacgag acagcttctc aaacagacgc acgccaaagg cgatattgtc atagatggac
    20281 atcgggaacg gcgtcggctt ctggaatacc atccccactt ttgcgcgcag cagcgcgata
    20341 tcctgggtgt tggtgagaat attgtcgcca tccagcagaa tttcaccttc cgcgcgctgc
    20401 tccggataaa gcgagtacat tttattgaag gtacgcagta gcgttgattt accgcagccg
    20461 gatggcccga taaatgccgt tacctgattc ttcgcgatat ccagattaat gttcttcagg
    20521 gcatggaatt tgccgtagta gaagttcaaa tcacgaacct gaatcttact cggggcagtt
    20581 tcaaccatac tcatttcact cttttcctca tccagcgccg catccgccac gccgtaaaat
    20641 aatgcctgat ggcgctacgc ttatcaggcc tacaatgtct ttaaccgtgt tttttcttcg
    20701 cgaaaacaac acgcgccaga atattcagca gcagtacgca cagggtaata atcagcacgc
    20761 ccgcccaggc taattgttgc cattcggcaa acgggctcat cgcgaattta aaaatggtca
    20821 ccggcaggtt ggcgatcggc tgcatcatgt cggtgctcca gaactggttc gagagcgcgg
    20881 taaacaacaa tggcgccgtt tccccggcga tacgcgcaat agccagcaga ataccggtca
    20941 taatcccgga gatagaggct ttcagcgtaa tcgcggagat catcttccac ttcggcgtac
    21001 ccagcgcata agcggcttca cgcaggctat ccggtaccag cttgagcatg ttttcagtgg
    21061 tacggataac gatcggcacc tgcaacagcg ccagcgcaat cacccctgcc cagccggaga
    21121 agtgctgcat ctgcgccacc acgatggtgt aaacaaacag ccccacaaca attgacggcg
    21181 cggaaagcag aatgtcgtta ataaagcgaa tgatttccgc cagccaggat ttacggccat
    21241 actcggccag gtaaataccc gccataatcc ccagcggcgt acccaatacg gtagcccaga
    21301 gaatcaataa tccactcccc gccagggcgt tcgccagccc gccgcccgcc gtgttcggcg
    21361 gcggcgtcat ttcggtaaac agcgccagcg acataccatc aatgccgcgc gtgatggtgg
    21421 acatcaaaat ccagatcagc cagaacaggc caaatgccat cgtcgccatt gagagcgtta
    21481 gtgcgatacg gttcttcatg cggcgacgcg cctgcatctt gcgacggaat tccgcgagct
    21541 gcgcggtgtt ctgcatatca agcgtagcca ttaacgtgct ccctcgttct tcgccagacg
    21601 cataatcatg aacttagacg ccgccaggac gataaaggtg atcacaaaca ggatcagccc
    21661 cagctccatc aacgctgcca cgtgcagacc cgattccgcc tcagcgaatt cgttggccag
    21721 cgcggaagtg atgctgttgc ccggcatata cagcgacgcg ctgtcgagct ggtaggtgtt
    21781 gccgatgata aaagtgaccg ccatcgtttc acccagagca cggcccagcc ccagcataat
    21841 gccgccgatc acgccatttt tggtgaacgg tagcacgatg cgccagataa cttcccaggt
    21901 agtacagccg ataccgtaag cggactcttt catcattacc ggcgtttgct cgaagacgtc
    21961 gcgcataacc gccgcaatgt aggggatgat catgatggcg aggatgacgc ccgccgccag
    22021 aataccgata ccaaaggccg ggccggagaa cagcgcgccg acaaacggaa tgttggaaag
    22081 aatattgccg accggctcct ggaagtacgt cgcaaacagc ggcgcgaaga taaacagccc
    22141 ccacatgccg tacacgatac tgggaattgc cgccagcagt tcaatggcga tgccgagcgg
    22201 acgcttcagc cagcctggcg ccagctcggt taaaaacagg gcaatgccga aactaaccgg
    22261 aacggcgatc agcagtgcga taaaggaggt taccagcgtg ccgtaaatgg gcaccagtgc
    22321 gccgtagata tcgtttggcg cgtcccactc cttagtccaa agaaatgaga aaccaaattt
    22381 ctgaatactt ggccaggagg agatgatcaa tgagacgata ataccgccca acatcaatag
    22441 cacaatcagc gcagccagtt ttaccagcgc gctgaaaatc atgtcgcctt ttttacccgg
    22501 cgggttaaaa gcaggcttgg ttgcagccat aaattactct ttccattaaa cgcattttac
    22561 gacgttgccc ctgccggatg gcgctacgat tatccggcct acaacgtggg cctgcggtcg
    22621 aaaccgtagg gcggataatc gtagcgccat ccgccaattc gttaattaat acagcgcctt
    22681 accgttgctg tcttttatac tggtcttcca ggcggtacga acctgatcaa caacgttatc
    22741 cggcaggctg gcgtagtcca gatcattcgc ctgtttagcg ccatttttgt aggcccagtc
    22801 gaagaacttc aacacttcag caccctgctc aggtttcttt tgcgctttgt ggaccaggat
    22861 aaaggtggtg gaggtgattg gccacacatc gtcacctttc tggttggtca gatcctgcgc
    22921 gaaggttttg ctccagtctg cgcctttcgc cgcattagag aagctctctt ccgtcgggct
    22981 taccggtttg ccgtcggcag aaaccagttt ggtgtaggcc aggttgttct gtttagcgta
    23041 agcgtattca acgtagccga tagcgcctgg cagacgctgt acaaatgccg cgatgccgtc
    23101 gttaccttta ccgcccagac cggttggcca gttcacggta gaacccgcgc ccactttcga
    23161 tttccactcg tcgttgactt tcgccaggta actggtgaac acgaaggagg taccggaacc
    23221 gtcagcgcga cgcaccacag cgatattctg tgagggcagc ttcacgcctg ggttcagttt
    23281 ggtgatggct tcatcatccc acttcttgat tttaccgagg tagatgtcac ccagcgtttt
    23341 accatccagc accagttcgc cggatttgag gcctggaata ttcaccgcca gcaccacgcc
    23401 gccgatcacc gtcggaaact ggaacaggcc ttcctgattc agtttttcgt cagacagcgg
    23461 cgcatcggaa gcgccaaaat caacggtatt cgcggtaatt tgtttcacgc cgccggaaga
    23521 gcctatcccc tggtaattga ctttgttacc ggtttctttc tggtaggtat ccgcccattt
    23581 ggcatacacc ggcgcaggaa acgttgcacc ggcacctgtc aggcttgctg ctgcaaaggc
    23641 agagaacgcg ctcatcgata aagtcgcggc gacaacagtt gcgacagtgg tacgcataac
    23701 tttcataatg tctcctgcac ggtttcggta aatcgttgtt tgagttgcta cgatgagcaa
    23761 aataggacaa attgatgaca gttatatgtc ttgattatga cggtttgatg acaatggaaa
    23821 taaaaaagct ggcccgggga gacaccagac cagcctgcag ggggagatga attaaactgt
    23881 ttgcgcaacc gcagacggtt tcaacagcgc gtacatcagg ccgcagacaa tcgtgcccag
    23941 ggcaatcgag agcaggtact gcatcacatg ttctaccgca tgcgggatcg ccaggacaaa
    24001 gagaccaccg tgtggcgcca tcagtgtaca accgaaatac atggacagtc ccccggcgat
    24061 tgcgccaccg accatcgtgg aagggatgac gcgcatcggg tcacgcgcag cgaagggaat
    24121 cgccccttca gagataaagc acagccccag gataaaggat gcgttacccg cttcatgctc
    24181 agaggcagtg aatttcgctc tggccgccca ggttgcgacg cccatcccta atgccggtac
    24241 catccctgcc gccataatgg ccgccatcgg catataggaa tgagaagcca gtaaaccgac
    24301 gccgaaggta tacgcagctt tattcaccgg cccaccaagg tcaaaacctt gcattgcgcc
    24361 cagcaacatt cccagcaaga tagcattcgt agaggtcata ttccccagga acgtcgtcag
    24421 cccttccatc accgcagaaa cggggccacc caccacgtaa atcatgatta ggccggtaat
    24481 cagcgtagac agtagcggca gaaccagtac cggcttaagc gcttccattg acgctggcag
    24541 cttaatattt tgcgccagaa accgtacgct gtaaccggcc agaaaaccgg ccacaatccc
    24601 tcccaggaaa ccagcaccgc acaggctggc caacatcccg ccaataagcc ccggggccag
    24661 acccggacga tcggcaattg agaaggcaat aaacccagcc agtaccggca ccatcagcgc
    24721 aaaggccgcc ttaccaccga tttgaaataa cgcagccgcc agcgtgcccg gctcattgaa
    24781 ggcctggata ccgaagacaa aagagagcgc gatacataac cctcccgcca ccaccaaagg
    24841 aagcatatgg gatacgccgg tcattaaatg cttataaacg ccgggtagct ctgttttacc
    24901 agctgaagaa gagcgcccgg cactcccctg atagacctcg gcgctattga aagcattatc
    24961 catttcctgc gcactctttt ttagcgccgc gccggtactg gtgcgataga gtcttttgcc
    25021 aacaaagcct gacagatcca gctcaatatc cgccgcgata atcaccacat ccgcttgcgc
    25081 tatctcttcc gcggtcagcg tgttcttcgc cccgacggaa ccgcgggttt caaccttgat
    25141 ccagtcacca cgcttgcggg cttcaatttc cagcgcttcg gcagccataa aggcatgggc
    25201 gacgcccgtc ggacaggccg tcacagcaac aattttttta gtcatagtag gataccctgt
    25261 tcttttaatt taaagaaaaa gcgggaaaaa atgttacaga cgtgaccagg ccgcggcttt
    25321 ctggaacagt gcgtcatccg ggcgaatccc ggtataaagg acaaattgct ccacggcctg
    25381 aatagcaaac acttcggaac cgataatcac ggttttaccg cgttcacggg cgtagcggat
    25441 tagcggcgtg acgggcggta gcgccaccac atcaaagata acgctcgcct tatccacttc
    25501 ttgttcggaa taagagagtt tgtcggcatc attaccgcca gccattccga taggcgtggc
    25561 gttaattaac aaatcggctt caataccgtc ggtatccggg cgccattcat agccatagag
    25621 ttcggccagt tgtttacctg acgcttcatc aatcgcgaca atataaccac gggtaaaccc
    25681 cgcatccttc agcgcgcagg ccaccgcctt tgccatacca ccgctgccac gcaaagcaaa
    25741 cacctggtcg ggagagacct tgtaattcgc cagcaagcga gctattgcaa tgtaatcggt
    25801 gttgtacgcc ttagcggaag catccagttc atccaccagc ggaatgcagg cttccttaaa
    25861 tggcatagag atcgcgcacc cacgtatccc cagcccgcgc acgccgctaa tggcctgcgt
    25921 aagatcggtc ggcgagaaag ctttgtagag ataattgaga tccagcgctt cgtacagata
    25981 gttgtgaaag cgtgtaccga agttacttgg gcgtgcagcc agggacatgc agacctgagt
    26041 gtctttatta atgcgctttg tcatgatgaa tcctcataga agttgcgata gagaaaatca
    26101 tcggctaaaa aggggatatt aaaaattgct cattcccgtt cgggaaattt catcttttat
    26161 ggcaacccgg cacactgaac aaaaatactt aaagctactc cagcactatg gcgataagcc
    26221 cgttagcgtg acgctacagg agctggcgga tgtgttgttc tgcacccggc ggcatatgcg
    26281 taatctgttg cttcagatgc aggaggcaaa gtggctcatc tggcaatcac aggccggacg
    26341 tgggcatcgc gcccggcttc acctgcgcta taaaccagaa cagctgttaa gcgaaaaggc
    26401 ggagcagttg ctggagtctg gtcatgttga tcaggccatt cagctgctgg gtaaaaataa
    26461 gcaccaggtg gcgcaactgc tgcgctcaaa actgggctat agcgtgcggg cagactatca
    26521 gcggctgtgc atcccctatt accggacaat gccgtcgctg tgccccggca taccgttgcg
    26581 tcgctctgag cagcatctgg tcaggcagat ttttagcggc ctgacgcgca taaatgagga
    26641 aaaaggtgaa gtcgaagccg atcttgccca ccactggcgg cagattgatc cactgcgctg
    26701 gcgtttttat ctgcgccccg ccgtcctctg gcatgatggt caggagctga cgatcgacgc
    26761 ggttatcgct tcactgaccc gcagcgctaa gctgccgttg ttctcgcact tgcagaccat
    26821 tcaggccacc gggccgctga gccttgaaat tacgctggcg cacccggata accgactgcc
    26881 gctgctgctc agccatattg atgccatgat cctaccgcct gaccatacac aacgcgctga
    26941 tttcccggca catcctgtgg ggactggccc ttatgaggtg gtggaaaaca atggctttca
    27001 tctgcaaatg aaggcctttg accactattt cggcctgcgc gggctgctgg atgaagtgga
    27061 ggtctttatc tggccgaatt taacggagac agacaacctg gcggaatcgc tgtcggataa
    27121 cgacacggca gcctggctca gttccagcct gagcgatgag gattacgttt ccggacggct
    27181 tagccaggta tcaggcaaac cttctgacaa cctgcgcgag atgtttcttg agcgtggagg
    27241 atatttttta ttatgcgaca gccgctcccc gcactggcat accgccgaac atcgccgctg
    27301 gctgcgggaa actctcagcc cttacgcctt actccagcat ctgagtgagg caattcgccc
    27361 cttctgggta ccgggcggca gcctgctgtc ctcctggttt catactattg aggcgggccc
    27421 ggcctgttca ccttttatct cgtcgtcgcc ctacgcaaaa cttcgtctgg cctatcacga
    27481 tcagcaccct gaatttccaa tgctcctgga tattatgcaa gagatcatgc gccagcaggg
    27541 cattttactt gagggcgttg agctgaatta tgatgactgg gcgaatggca aaaccaatgt
    27601 ggatctctgg ctggggacgg tcaatttccc cattcccgaa gagtggaacg tcggtacatg
    27661 gctactgggc tcccctttac tgcgccacgc catcagcggt ggggatgatg cgctgctggc
    27721 ccaatgggaa acccagtggc atgccgaaac catcagcgcg gaacaactgg tcagggaaac
    27781 cacccgttca ggctggctac agccgctttt tcaccactgg atgcgactca aaagccccga
    27841 ccgggccagg gggatccacc tgaataacct gggatggttt gatttccgat ccacctggat
    27901 tgagccaggg ccgtagttca ttgatatgac ttattttgta attagattag ttcgttattt
    27961 ccagcgtgat cgtggcgtaa gcttcaaatg taccaggttg aggccgcgct cccgtcgcgc
    28021 tggcaggcgc ggcagaaaaa gtcaatgagt tagtctcggc gccgccatta ttgacgccca
    28081 tatccatatc catttttccg cctgtcacct taaccatccg atcccatttg tcataaatca
    28141 taattccgac atcatcatta cccagaactt tcatcatatt tgcgctggaa tcaacgggat
    28201 cagcattaaa tgtcgaatag acgatattct catccaacat tccggtacat ttcacctgta
    28261 ccgttttagt cactttatga cccgcagcag cggtgccttg cgttgtcgag aaatccgcaa
    28321 ccgggatctt accgaaattc acctctatca cctggccgga atcaatttca cagctctgcg
    28381 gcgccacgat atcgccaaca attctgactt ccgccaattt gtcggtactg gcagtcgagg
    28441 agctggcatc aagccccccg tataaattag ccacaatcgt gccaggaatg gcaacctgac
    28501 cgacaaacgg tttattgata aggaaagaga ccttgacctc cgacccggta tataacgttg
    28561 cgagattgcc ctcaacggta tcggtataac aattcatccc atcttttact acattaggtt
    28621 cagcctcaaa gggaaccgca ataaagcctc gtccaagaac agcaatcgac gttgcaatac
    28681 ttaggttatc gttaagcgta tagtaggtgt aaccatttct ggtggtatca atactcagcg
    28741 gcgaacgagc ggtataatag acttcacgaa acgtcgatga aaaatgggtc aaacagctac
    28801 agccaacttt atatgattct gacgatgtta atgtctccag atccctgacc tctgttccgg
    28861 ctttattttt ttctgcggga atccgggcgt cattgagatt aaggttataa atataagtcc
    28921 ctttaaccgc atgacaaatg ccatcgccag cccggcaaac aggcgaaata agaaccataa
    28981 agcatgaaaa taatattatt gtccataagc gcataattaa attccttatt ggcaagtgac
    29041 ggcttgctgc accagttcag cattctctgt tttatgacct aacgtataat taacggcaca
    29101 tgttgttgat tcatcaccgc cccaacttag agtgaaatga ccgttttccg gcatccccga
    29161 taaatagagt tcgccgttat cgccgacaat cccggttacc gttccggaat ccagctccgc
    29221 cgacgccatc gcgccaaacg gcgcaggttt gccattcact tgcatcacat taaacaacac
    29281 gcgataaccg acatgcgtca caaacgccgc tttcaccacg gcgccgcgcg ttggcaccag
    29341 attgactacc gtgttatcca gctcaatatt ggctttggca aaatagttgc tgtcaatcgc
    29401 catgcggttt tcgtcgtacg ggttaagctg cgttttcacc gtatagcccc gccagtctgt
    29461 agcaacccca gtcgtgtttt ctacggtaag gccatcagca cccggcgctt ccaccagcgc
    29521 gacggtttcc cccaactcct gcgagaaggt cacaccgccg ctgtgaacca ggatgccgcc
    29581 gcgggcgcca tagttcagcg tttgtgaatc acggctccag gcataaccgc cgtttactga
    29641 accataagta ccgtcatacc ccatgctggc gttaccacca taggtatcct ccggcgtact
    29701 ggtccaggat tcctgcacgt tataggaaag attgtggccc tccagcaacg tgccgccaac
    29761 gccagcctgc attgtgctgt cgttatgatt attttgcgtc atcgagtagt taacgtagct
    29821 gctctccttc gcccctgaaa gcgggatgga aaccgtcagc atgaatatct gttcgtgatc
    29881 gctgtcatcg ttgtcgtttt tattattgct gccggaagaa cgattcgcag agtcggtata
    29941 gttccacgac gcgttccacg aaattcgccg ccagctattg ctatagccaa actgcaccag
    30001 gcgctcgact tcatccgttt gccagtattg ctgacggctt aacgtcagat aaatgttgcc
    30061 aaaaccgggg ccaaatgatt gcgtccaggt tccttccacg cggctacggc ggttgcccgt
    30121 ctcccagaaa tcagagctgt tgtcctgcct cgatgcccac tcgccgaggg tgtaatagcc
    30181 ttccgtggaa taacggtacc ccaccagacg gaaactggtg tcggtatcat caaaacgttt
    30241 ggagtagaga aaacgccagg actggccgct ttcattatca ccatcgtcaa agtgtgaacg
    30301 ggcgtgggtc acatcaaacg atacggcccc gatcgacccc atatctttac ccataccaag
    30361 cgcggcggaa gcataatctt ccgcaacctg cgtgccgcca tagagcgtta atccccatgg
    30421 caggccatgc aacacctgcg cctgaacgac gttaggggta aatccgcttt catcgcgcat
    30481 ttcaccgacg ctaatatcaa aatcggtctg gccttcacgc ttcagtatcg ccagcgacgc
    30541 gtacggctgg gtaaagtgct gctcgctgcc gtcttcttct tttatggtga catcaagatc
    30601 gccgccgccg ctggtggtgt tcaggtcggt gatctcgaaa gcgccctgcg gcacggctga
    30661 ctgataaatg acatatctat tctgccggat gatgacggtg gcgttacttt tcgccacccc
    30721 gcgaaccact ggcgcaaacc cgttctggct cgacggtagc atgtcatcgt cggtatagag
    30781 tctgaccccg cggatctggg cgctatcaaa gacataactc gccgtccagg tgtcgccgac
    30841 cataatctgg ctgcgcagcg cggcgatatc gcgctggaca tagctactga tggagtgata
    30901 ttccgtgtcg ctgccggtgg cgctcagcgt actgtagtta cgcaaccgcc atgctcccag
    30961 gttaatcccg ttacgcaggt tcagataata agagtcatcg ttcccattgt cgtaattaga
    31021 ctttaccgtg tgcgatccgg aaaaatctta attgaccatc atcgcattga tgccctcatc
    31081 ccagcgtgac gggctgatat agtcataggc cgccgtgttc agatagatct gtggaacaga
    31141 tatatttaac gccagcttat tcgcatctaa taaccaggtg gtgccatcaa ttaacggaac
    31201 gggattcacg caggctgtat tatcgacatc ctgcaagcct ttcaccgcgt ctaccttaac
    31261 accatacgac gacaatacat ccttaaccgc gacaaagcag ggatgcagtt cggcatccgg
    31321 ttgatcctgc acaaaggtca catcccgtcg ttcaaacagt ttcccgttaa tgacgatatc
    31381 gaccttataa tcgcccggcg gcaacgcgtt ggaacggtta aactgatgaa tatccacgtc
    31441 cacggggtga tcgatttcca gcaaaccagg gttaaatagc gtttccctag ccattgtcgg
    31501 gaaagcgata ctcagataag cacctgaaat caagacgagg caaagacgag ggtgaatcat
    31561 caagatatcc ttatcgcaaa actaaagcgc ttgcttaaca gggctactaa tcgcgccgta
    31621 atcattaata aaacgccagg ctaaagcgtg ccccgtaaca ccagtaggta aatccagcgt
    31681 taatttttca aaaggcttta tcatattcaa tggaacatct ttaccgtcta cagagacatc
    31741 catgatattc atatgaatag gactattatt ttctacaacc agtttacttc cctgtcgata
    31801 ccatttgact ttagctaccg ccttttccgg gataagcgta atagaggccg ggcgccagaa
    31861 taacttgata cgcgttttaa ttgcgatctc aagcgtactg ctatctttat ttttactgga
    31921 tggcggaatg tttttcacat taaaccaaaa aacagattcg cgatcctttg gcaactcacc
    31981 cgctgtttta ataatgcgca gcactttttc ctgactcggc tcaagacgag aaacaggcgg
    32041 aatgacggta aaaggtggtt tgctcttatc atccttactg aaaggatcaa cccatacttg
    32101 tattagataa ggcaaatcaa cttctttatt gtaaatagaa atagtagagt caggatcgtt
    32161 gccatgaaaa atgacgcgag ttccaccgac cacaatacct gcaaaagcag agggaagatt
    32221 aaggcacagg agtgccagaa taactatttt tattccacga gcaaacatag acaaactcat
    32281 ccctggataa aaaagacgcc gggcatttat acaactacag ttgttcacaa tggcaggcgt
    32341 caataaatta ataaaagacg tttaagaaga gcgaatctta tttttggtat tcgacagtga
    32401 actgagaatc tgcgttagca gtacccgcag tgacggttgc gtcagtggcg atataacgcg
    32461 cgataaactc catagaagcc gtacccgctg tggtatcaat cgtgctatac gcagaatcgt
    32521 tgtacagttt aacttgtgag ttatccgcgc ggttgtaaat acggatcgct acgccagatg
    32581 ctgtaatggc agcgccgtca ccggtgtaat cacccggggc atcgccatta gcagggttgc
    32641 cgatagccag gtcgccatcg ctgttggaag cttcggtacc atcaaaacga acggcagcct
    32701 tagtatacgt agccgggcac ccggtcaggt cgatatggaa ctcggtaggc gcagcggtac
    32761 ttcccacgcc agcaaatgcc gttttgttaa ctttgcctaa attaacgttt tgatcagcgg
    32821 tttgtggcgt aacctggcag gtgctgtcaa ccacttcacc aaggaagtga acggtgccat
    32881 cagatgccat tgcattacct accagcatag tagaagacag aaccagagcg
//
LOCUS       DAJVBX010000023        32572 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.023, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000023 DAJVBX010000000
VERSION     DAJVBX010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 32572)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32572)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32572
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.023"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            44..607
                     /gene="srlA"
                     /locus_tag="OPV72_000976"
                     /gene_synonym="gutA"
     CDS             44..607
                     /gene="srlA"
                     /locus_tag="OPV72_000976"
                     /gene_synonym="gutA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HCR9913343.1"
                     /translation="MIETITHGAEWFIGLFQKGGEVFTGMVTGILPLLISLLVIMNAL
                     INFIGQQRIERFAQRCAGNPLSRYLLLPFIGTFVFCNPMTLSLGRFMPEKYKPSYYAA
                     ASYSCHSMNGLFPHINPGELFVYLGIASGLTTLGLPLGPLAVSYLLVGLVTNFFRGWV
                     TDLTTAIFEKKMGIQLEQKVHLTGAVS"
     gene            604..1575
                     /locus_tag="OPV72_000977"
     CDS             604..1575
                     /locus_tag="OPV72_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HCR9913344.1"
                     /translation="MTRVRIEKGAGGWGGPLELDVTPGKKIVYITAGTRPAIVDKLAQ
                     LTGWQAVDGFKEGEPPEAEIGAAIIDCGGTLRCGIYPKRRIPTINIHSTGKSGPLAQY
                     IVEDIYVSGVKEENITLVGETSARPQPAKTTLGRDYDTSKKITEQSDGLLAKVGMGMG
                     SAVAVLFQSGRDTIDTVLKTILPFMAFVSALIGIIMASGLGDWIAHGLAPLASHPLGL
                     VTLALICSFPLLSPFLGPGAVIAQVIGVLIGVQIGLGNIPPHLALPALFAINAQAACD
                     FIPVGLSLAEAKQDTVRVGVPSVLVGRFLTGAPTVLIAWFVSGFIYQ"
     gene            1587..1949
                     /gene="srlB"
                     /locus_tag="OPV72_000978"
                     /gene_synonym="gutB"
     CDS             1587..1949
                     /gene="srlB"
                     /locus_tag="OPV72_000978"
                     /gene_synonym="gutB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HCR9913345.1"
                     /translation="MSVIYQTTITRIGQSAMEALGEKMLITFREGAPADIEEFCFIHC
                     HGELTGALQPGARCELGQHCYPVTAVGSVAEQNLRELGHITLRFDGLREAEFPGTVHV
                     AGPVPDDIAPGCILTFVA"
     gene            1961..2740
                     /gene="srlD"
                     /locus_tag="OPV72_000979"
     CDS             1961..2740
                     /gene="srlD"
                     /locus_tag="OPV72_000979"
                     /EC_number="1.1.1.140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sorbitol-6-phosphate dehydrogenase"
                     /protein_id="HCR9913346.1"
                     /translation="MNQVAVVIGGGQTLGAFLCRGLAEEGYRVAVVDIQSDKAANVAQ
                     EINADFGEGMAYGFGADATSEQSVLALSRGVDEIFGRVDLLVYSAGIAKAAFISDFQL
                     GDFDRSLQVNLVGYFLCAREFSRLMIRDGIQGRIIQINSKSGKVGSKHNSGYSAAKFG
                     GVGLTQSLALDLAEYGITVHSLMLGNLLKSPMFQSLLPQYATKLCIKPDEVEQYYIDK
                     VPLKRGCDYQDVLNMLLFYASPKASYCTGQSINVTGGQVMF"
     gene            2817..3176
                     /gene="gutM"
                     /locus_tag="OPV72_000980"
     CDS             2817..3176
                     /gene="gutM"
                     /locus_tag="OPV72_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HCR9913347.1"
                     /translation="MVSTLITVAVIAWCAQLALGGWQISRFNRAFDKLSQQGRVGVGR
                     SGGRFKPRVVVAVALDEQQRVTDTLLMKGLTVFARPVKIAAMQGKHLHELQPDVIFPH
                     DSLAQNALSLALKLKHG"
     gene            3375..4148
                     /gene="srlR"
                     /locus_tag="OPV72_000981"
                     /gene_synonym="gutR"
     CDS             3375..4148
                     /gene="srlR"
                     /locus_tag="OPV72_000981"
                     /gene_synonym="gutR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucitol operon DNA-binding transcriptional
                     repressor SrlR"
                     /protein_id="HCR9913348.1"
                     /translation="MKPRQRQAAILEHLQKQGKCSVEELAQYFDTTGTTIRKDLVILE
                     NAGTVIRTYGGVVLNKEESDPPIDHKTLINTHKKALIAAAAVKYIHDGDSIILDAGST
                     VLQMVPLLSRFSNITVMTNSLHIVNALSELDNEQTILMPGGTFRKKSASFHGQLAENA
                     FEQFSFDKLFMGTDGIDLNVGVTTFNEVYTVSNAMCNAAREVILMADSSKFGRKSPNV
                     VCSLETVDKLITDAGIDPAFRQALEAKGIEVIITGESNE"
     gene            4141..5106
                     /gene="gutQ"
                     /locus_tag="OPV72_000982"
     CDS             4141..5106
                     /gene="gutQ"
                     /locus_tag="OPV72_000982"
                     /EC_number="5.3.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311591.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose-5-phosphate isomerase GutQ"
                     /protein_id="HCR9913349.1"
                     /translation="MSDALLNAGRQTLMLELQEASRLPERLGDDFVRAANIIIHCEGK
                     VIVSGIGKSGHISKKIAATLASTGTPAFFVHPAEALHGDLGMIESRDVMLFISYSGGA
                     KELDLIIPRLEDKSVALLAMTGKPHSPLGRAAKAVLDISVEREACPMHLAPTSSTVNT
                     LMMGDALAMAVMQARGFNEEDFARSHPAGALGARLLNNVHHLMRQGDAIPQVMLATSV
                     MDAMLELSRTGLGLVAVCDEQHVVKGVFTDGDLRRWLVGGGALTTPVSEAMTPNGITL
                     QAQSRAIDAKELLMKRKITAAPVVDENGKLTGAINLQDFYQAGII"
     gene            complement(5103..6623)
                     /gene="norR"
                     /locus_tag="OPV72_000983"
     CDS             complement(5103..6623)
                     /gene="norR"
                     /locus_tag="OPV72_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase transcriptional regulator
                     NorR"
                     /protein_id="HCR9913350.1"
                     /translation="MSFSVEVLAGIAIELQRGIGHQDRFQRLITTLRQVLACDASALL
                     RYESRQFIPLAIDGLAQDVLGRRFTLEGHPRLEAIARAGDVVRFPADSDLPDPYDGLI
                     PGQESLKVHACVGLPLFAGQNLIGALTLDAMTPEQFEVFSDEELRLVAALAAGALSNA
                     LLIEQLESQNMLPGSSGVFEPIKETHMIGLSPAMTQLKKEIEIVAGSDLNVLIGGETG
                     TGKELVAKAIHQGSPRAVNPLVYLNCAALPESVAESELFGHVKGAFTGAISNRSGKFE
                     MADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRSLRVDVRVLAATNRDLREE
                     VLAGRFRADLFHRLSVFPLFVPPLRERGDDVVLLAGYFCEQCRLRLGLSRVVLSPGAR
                     RHLLNYGWPGNVRELEHAIHRAVVLARATRAGDEVVLEEQHFALSEDVLPAPSAESFL
                     ALPACRNLRESTENFQREMIRQALAQNNHNWAASARALETDVANLHRLAKRLGLKD"
     gene            6809..8248
                     /gene="norV"
                     /locus_tag="OPV72_000984"
     CDS             6809..8248
                     /gene="norV"
                     /locus_tag="OPV72_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic nitric oxide reductase
                     flavorubredoxin"
                     /protein_id="HCR9913351.1"
                     /translation="MSILVKNNIHWVGQRDWEVRDFHGTEYKTLRGSSYNSYLIREEK
                     NVLIDTVDHKFSREFVQNLRSEIDLADIDYIIINHAEEDHAGALTELMAQIPDTPIYC
                     TANAIDSINGHHHHPEWNFKVVKTGDTLDIGDGKQLIFVETPMLHWPDSMMTYMTGDA
                     VLFSNDAFGQHYCDEHLFNDEVDQTELFEQCQRYYANILTPFSRLVTPKITEILGFNL
                     PVDMIATSHGVVWRDNPTQIVELYLKWAADYQEDRITIFYDTMSNNTRMMADAIAQGI
                     NEVDPNVAVKIFNVARSDKNEILTNVFRSKGVLVGTSTMNNVMMPKIAGLVEEMTGLR
                     FRNKRASAFGSHGWSGGAVDRLSTRLQDAGFEMSLSLKAKWRPDLDALELCRQHGRDI
                     ARQWALAPLPETTQKTAPVEETTTCTAADLGPKMQCSVCQWIYDPALGEPLQDVAPGT
                     PWSDVPDNFLCPECSLGKDVFDVLATEAK"
     gene            8245..9378
                     /gene="norW"
                     /locus_tag="OPV72_000985"
     CDS             8245..9378
                     /gene="norW"
                     /locus_tag="OPV72_000985"
                     /EC_number="1.18.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:flavorubredoxin reductase NorW"
                     /protein_id="HCR9913352.1"
                     /translation="MSRGIIIIGSGFAARQLVKNIRKQDAHVPLTLIAADSMDEYNKP
                     DLSHVISQSQRADDLTRQLAGEFAEQFNLRLFPHTWVTDIDADAHVVKSQDKQWQYDK
                     LVLTTGATAFVPPIAGRELMLTLNSQQEYRACETPLRDAQRVLIVGGGLIGSELAMDF
                     CRAGKTVTLMDNAASLLASLMPPEVSSRLQHHLTDMGVHLLLKSQLQKLEKTEAGIRA
                     TLVSQHSIEVDAVIAATGLRPETALARRAGVAVNRGVCVDSYLQTSHPDIYAIGDCAE
                     INGQVLPFLQPIQLSAMYLAKNLLGGNAPLKLPAMLVKVKTPELPLHLAGETQRRDLS
                     WQITAESDGMIAKGMSGEGQLRAFVVSEDRMKEAFALLKTLSV"
     gene            complement(9475..11715)
                     /gene="hypF"
                     /locus_tag="OPV72_000986"
     CDS             complement(9475..11715)
                     /gene="hypF"
                     /locus_tag="OPV72_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyltransferase HypF"
                     /protein_id="HCR9913353.1"
                     /translation="MAIDTPSGVQLRIRGKVQGVGFRPFVWQLAQQLQLHGDVCNDGD
                     GVVVRLLEDPSQFIAALYQDCPPLARIDSVEHASLVWERAPTDFTIRQSAGGSMNTQI
                     VPDAATCPACLAEMNTPGERRYRYPFINCTHCGPRFTIIRAMPYDRPFTVMAAFPLCP
                     ECDSEYRDPYDRRFHAQPVACPSCGPHLEWRSQHERAEKEAALQAAVAQLNAGGIIAV
                     KGLGGFHLACDARNDNAVAMLRARKHRPAKPLAVMLPTAQTLPTAARSLLTTPAAPIV
                     LVDKQYVPSLSEGIAPGLTEVGVMLPANPLQHLLLQALNYPLVMTSGNLSGKPPAITN
                     EQALDDLHDIADGFLLHNRDIVQRMDDSVVRDSGEMLRRSRGYVPDAIALPPGFRDVP
                     PILCLGADLKNTFCLVRGEQAVVSQHLGDLSDDGIQAQWREALRLIQSIYDFTPERIV
                     CDAHPGYVSSQWASEMRLPTETVLHHHAHAAACLAEHGWPLDGGEVIALTVDGIGMGE
                     NGALWGGECLRVNYRECEHLGGLPAVALPGGDLAAKQPWRNLLAQCLRFVPDWQNYPE
                     TAGLQQQNWSVLARAIERGVNAPLASSCGRLFDAVAAALRCAPASLSYEGEAACALEA
                     LASQCANVEYPVTMPLNGAQLDVAVFWRQWLNWQATPAQRAWAFHDALACGFATLMRQ
                     QATARGITTLVFSGGVIHNRLLRARLAFYLSDFKLLFPQRLPAGDGGLSFGQGVIAAA
                     RALREV"
     gene            complement(11861..12406)
                     /gene="hydN"
                     /locus_tag="OPV72_000987"
     CDS             complement(11861..12406)
                     /gene="hydN"
                     /locus_tag="OPV72_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport protein HydN"
                     /protein_id="HCR9913354.1"
                     /translation="MNRFIIADASKCIGCRTCEVACVVSHQENQDCASLTPETFLPRI
                     HVIKGVNVSTATLCRQCEDAPCANVCPNGAISRDKGFVHVMQERCIGCKTCVVACPYG
                     AMEVVVRPVVRNSGAGLNVRAEKAEANKCDLCHHREAGPACMAACPTHALICVDRNKL
                     EQLSAEKRRRAALDSTASLLF"
     gene            complement(12607..13416)
                     /locus_tag="OPV72_000988"
     CDS             complement(12607..13416)
                     /locus_tag="OPV72_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913355.1"
                     /translation="MLPGIGGKKNVKIIVWSGLLFLCLAARALATGVVGYLPMSDGEY
                     AQKRALKPLLILPYSVSPDQTWHFRQVGVSSVTLLPEPKKDNEWRISGKDRAGNSWVV
                     PVGRLINLAGNAQFYRADLDRNGIQDLVIWLGNPGLGLAPSAQYIIFTFLKNGRPCVF
                     EPWGFYTATDTGVDDLLDLQGNGRTQLLDMQFDSGYWITNLYQVKDARWQRVHGWFGR
                     LSYPALTRFNHYPGRKLIIKPIAGRNPQTDDLSLTQRCLIRGNVLPGVNQD"
     gene            complement(13443..13913)
                     /gene="hycI"
                     /locus_tag="OPV72_000989"
     CDS             complement(13443..13913)
                     /gene="hycI"
                     /locus_tag="OPV72_000989"
                     /EC_number="3.4.23.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation peptidase HycI"
                     /protein_id="HCR9913356.1"
                     /translation="MTDVLLCVGNSMMGDDGAGPLLAEMCAAQPKGNWVVIDGGSAPE
                     NDIVAIRELRPQRLLIVDATDMGLNPGEIRIIDPDDIAEMFMMTTHNMPLNYLIDLLK
                     EDVGEVIFVGIQPDIVGFYYPMTQPIKDAVNIVYQRLEGWQGNGGFAALDAPEA"
     gene            complement(13906..14316)
                     /locus_tag="OPV72_000990"
     CDS             complement(13906..14316)
                     /locus_tag="OPV72_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase maturation HycH family
                     protein"
                     /protein_id="HCR9913357.1"
                     /translation="MSEQVVFSQLSRKFIDENDATPAEAQQVVYYSLAIGHHLGVIDC
                     LEAALTCPWDEYLAWIATLEAGSDARRKMEGVPKYGEIVIDFNHVQMLARAFDEARAA
                     QTPQQQEWSKLMLSMLHDIHQESAIYLMVRRLRD"
     gene            complement(14313..15080)
                     /gene="hycG"
                     /locus_tag="OPV72_000991"
     CDS             complement(14313..15080)
                     /gene="hycG"
                     /locus_tag="OPV72_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycG"
                     /protein_id="HCR9913358.1"
                     /translation="MSNLLGPRDANGIPVPMTVDESIASMKASLLKNIKRSAYVYRVD
                     CGGCNGCEIEIFATLSPLFDAERFGIKVVPSPRHADILLFTGAVTRAMRSPALRAWQS
                     APDPKICISYGACGNSGGIFHDLYCVWGGTDKIVPVDVYIPGCPPTPAATLYGFAMAL
                     GLLEQKIHARAPGELDDQPAEILHPDMVQPLRVKVDRAACRLAGYRYGRQIADDYLTQ
                     LGQGEQQVARWLEAENDPRLTEIVIHLNHVVEEARIR"
     gene            complement(15080..15622)
                     /gene="hycF"
                     /locus_tag="OPV72_000992"
     CDS             complement(15080..15622)
                     /gene="hycF"
                     /locus_tag="OPV72_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycF"
                     /protein_id="HCR9913359.1"
                     /translation="MFTFIKKVIKTGTATSSYPLEPIAVDKNFRGKPEHNPQQCIGCA
                     ACVNACPSNALTVETDLATNELAWQFNLGRCIFCGRCEEVCPTAAIKLSQEYELAVWK
                     KEDFLQQSRFALCNCRVCNRPFAVQKEIDYAIALLAHNGDSRAENHRESFETCPDCKR
                     QKCLVPSDRIELTRHMKEVS"
     gene            complement(15632..17341)
                     /gene="hycE"
                     /locus_tag="OPV72_000993"
     CDS             complement(15632..17341)
                     /gene="hycE"
                     /locus_tag="OPV72_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycE"
                     /protein_id="HCR9913360.1"
                     /translation="MFEEKLGQQYLAALHQAFPGVVMDEAWQTKDQLTITVKVNYLPE
                     VVEFLYYQQGGWLSVLFGNDERQLCGHYAVYYVLSMEQGTKCWITVRVEVDANKLEFP
                     SVTPRVPAAVWGEREVRDMYGLIPVGLPDERRLVLPDDWPDELYPLRKDSMDYRQRPA
                     PTTDAETYEFINELGDKKNNVVPIGPLHVTSDEPGHFRLFVDGENIIDADYRLFYVHR
                     GMEKLAETRMGYNEVTFLSDRVCGICGFAHSTAYTTSVENAMGIQVPERAQMIRAILL
                     EVERLHSHLLNLGLACHFTGFDSGFMQFFRVRETSMKMAEILTGARKTYGLNLIGGIR
                     RDLLKEDMIQTRQLAQQMRRDVQELVDMLLSTPNMEQRTVGIGRLDPEIARDFSNVGP
                     MVRASGHARDTRADHPFVGYGLLPMEVHSEQGCDVISRLKVRINEVYTSLNMIDFGLD
                     NLPGGPLMVEGFTYIPHRFALGFAEAPRGDDIHWSMTGDNQKLYRWRCRAATYANWPT
                     LRYMLRGNTVSDAPLIIGSLDPCYSCTDRMTVVDVRKKKSKVVPYKELERYSIERKNS
                     PLK"
     gene            complement(17359..18282)
                     /locus_tag="OPV72_000994"
     CDS             complement(17359..18282)
                     /locus_tag="OPV72_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="respiratory chain complex I subunit 1 family
                     protein"
                     /protein_id="HCR9913361.1"
                     /translation="MSVFYPLIQALVLFAVAPLLSGITRVARARLHNRRGPGVLQEYR
                     DIIKLLGRQSIAPADSGWVFRLTPFVMVGVMLTIATALPVVTVGSPLPQLGDLITLIY
                     LFAIARFFFSIAGLDTGSPFTAIGASREAMLGVLVEPILLLGLWVAAQVAGSTHISNI
                     ADTIYHWPVARSIPLILALCACAFATFIEMGKLPFDLAEAEQELQEGPLTEYSGSGFA
                     VLKWGISLKQLVVLQMFVGVFLPWGQMETFSAGGLLLALVIAVVKLIVGVLVIALFEN
                     SMARLRFCATSRVTWAGFGFAFLAFVSLLAA"
     gene            complement(18285..20111)
                     /gene="hycC"
                     /locus_tag="OPV72_000995"
     CDS             complement(18285..20111)
                     /gene="hycC"
                     /locus_tag="OPV72_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461772.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit 3"
                     /protein_id="HCR9913362.1"
                     /translation="MSSLSLITSGVAWFAAAAVLAFLFSFHKALSGWIAGIGGAVGSL
                     CTAGAGFTALTSAVTVSGVMPFTGHMLQITPLNAIWLITLGLCGLFVSLFNIDWHRHP
                     QVKANGLLINLLMAAAVCAVVASNLGTMVVMAEIMALCAVFLTGGSKEGKLWFALGRL
                     GTLLLAIACWLVWQRYGTLDLGLLDQRAQQLPLGSDIWLLGVIGFGLLAGIIPLHGWV
                     PQAHANASAPAAALFSTVVMKIGLLGILSLSLLGGNAPLWWGVALLVLGMITAFVGGL
                     YALMEHNIQRLLAYHTLENIGIILLGLGAGVTGIALNQPVLIALGLTGGLYHLLNHSL
                     FKSVLLLGAGSIWFRTGHRDIEKLGGIGKRMPVISIAMLVGLMAMAALPPLNGFAGEW
                     VIYQSFFKLGNSGAFVGRLLGPLLAVGLAITGALAVMCMAKVYGVTFLGAPRTKEAEN
                     ASCAPILMGVSVVALAVCCVLGGVAAPWLLPMISTAVPLPLETAHTTVSQPMITLLLV
                     ACPLLPFIIMAMFKGNRLPSRSRGAAWVCGYDHEQSMVITAHGFAMPVKEAFAPVLKL
                     RKWLNPVSLVPGWQNAAAAGLFRRLALIELAVLVVIVVSRGA"
     gene            complement(20111..20719)
                     /gene="hycB"
                     /locus_tag="OPV72_000996"
     CDS             complement(20111..20719)
                     /gene="hycB"
                     /locus_tag="OPV72_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycB"
                     /protein_id="HCR9913363.1"
                     /translation="MNRFVIADSTLCIGCHTCEAACSETHRQHGLQSMPRLKVMLNEK
                     ESAPQLCHHCEDAPCATVCPVNAINRVDGAVQLNESLCVSCKLCGIACPFGAIEFSGS
                     RPLHIPANANTPKAPPAPPAPARVSTLLDWVPGVRAIAVKCDLCSFDEQGPACVRMCP
                     TKALHLVENTDIARASKRKRELTFNTDFGDLTLFQQAQSGDA"
     gene            complement(20865..21326)
                     /gene="hycA"
                     /locus_tag="OPV72_000997"
     CDS             complement(20865..21326)
                     /gene="hycA"
                     /locus_tag="OPV72_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase regulator HycA"
                     /protein_id="HCR9913364.1"
                     /translation="MTIWEISEKADYIAQRHRRLQDQWHIYCNSLVQGITLSKARLHH
                     AMSCAPERDLCFVLFEHFRIYVALADGFNSHTIEYYVETKDGEDKQLIAQAQLDIDGK
                     VDERVNNRDREQVLEHYLEKIASVYDSLYTAVETNSPVNLRQLVKGHSPAV"
     gene            21536..21892
                     /gene="hypA"
                     /locus_tag="OPV72_000998"
     CDS             21536..21892
                     /gene="hypA"
                     /locus_tag="OPV72_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation nickel metallochaperone
                     HypA"
                     /protein_id="HCR9913365.1"
                     /translation="MHEITLCQRALELIEQQASAYGAKRVTAVWIKIGAFSCVETSAL
                     SFCFDLVCRGTIAEGCKLHLEEQEAECWCEHCQQYVTLLTHRVRRCPQCHSDTLRIVA
                     DDGLQIRRIEIDETED"
     gene            21962..22834
                     /gene="hypB"
                     /locus_tag="OPV72_000999"
     CDS             21962..22834
                     /gene="hypB"
                     /locus_tag="OPV72_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase nickel incorporation protein HypB"
                     /protein_id="HCR9913366.1"
                     /translation="MCTTCGCAEGNLYIEGDEHNPHSAFRSAPFAPAARPALNITGIK
                     TPDFTPSQTAEGDLHYGHGEAGTHAPGMSQRRMLEVEIDVLDKNNRLAERNRARFAAR
                     QQLVLNLVSSPGSGKTTLLTETLMKLKDRVPCAVIEGDQQTVNDAARIRATGTPAIQV
                     NTGKGCHLDAQMIADAAPRLPLDDHGILFIENVGNLVCPASFDLGEKHKVAVLSVTEG
                     EDKPLKYPHMFAAASLMLLNKVDLLPYLNFDVEKCIASAREVNPEIEIILISATSGEG
                     MDQWLAWLEAQRCA"
     gene            22825..23097
                     /gene="hypC"
                     /locus_tag="OPV72_001000"
     CDS             22825..23097
                     /gene="hypC"
                     /locus_tag="OPV72_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 3 maturation protein HypC"
                     /protein_id="HCR9913367.1"
                     /translation="MCIGVPGQIRAIDGNQAKVDVCGIQRDVDLTLVGSCDENGQPRL
                     GQWVLVHVGFAMSVINEAEARDTLDALQNMFDVEPDVGALLYGEER"
     gene            23097..24218
                     /gene="hypD"
                     /locus_tag="OPV72_001001"
     CDS             23097..24218
                     /gene="hypD"
                     /locus_tag="OPV72_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461778.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase formation protein HypD"
                     /protein_id="HCR9913368.1"
                     /translation="MRFVDEYRAPEQVMQLIEHLRERAALLPYTAERPLRIMEVCGGH
                     THAIFKFGLDQLLPENVEFIHGPGCPVCVLPMGRIDSCVEIASHPEVIFCTFGDAMRV
                     PGKQGSLLQAKARGADVRIVYSPMDALKLAQDNPTRKVVFFGLGFETTMPTTAITLQQ
                     AKQRDVRNFYFFCQHITLIPTLRSLLEQPDNGIDAFLAPGHVSMVIGTEAYQFIAADF
                     HRPLVVAGFEPLDLLQGVVMLVEQKIAALSQVENQYRRVVPDAGNMLAQQAIADVFCV
                     NGDSEWRGLGVIESSGVHLTPEYQRFDAEAHFRPAPQQVYDDPRARCGEVLTGRCKPH
                     QCPLFGKTCNPETAFGALMVSSEGACAAWYQYRQQECEV"
     gene            24215..25225
                     /gene="hypE"
                     /locus_tag="OPV72_001002"
     CDS             24215..25225
                     /gene="hypE"
                     /locus_tag="OPV72_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417210.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase expression/formation protein HypE"
                     /protein_id="HCR9913369.1"
                     /translation="MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLELA
                     QLTAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEE
                     GLPMETLKSVVNSMAATAREAGIAIVTGDTKVVQRGAADKLFINTAGMGAIPADIHWG
                     AQTLSVGDVLLVSGTLGDHGATILNLREQLGLDGELASDCAVLTPLIQTLRHIDGVKA
                     LRDATRGGVNAVAHEFAASCGYGIELSESALPLKPAVRGVCELLGLDALNFANEGKLV
                     IAVERQAADRALAALRAHPLGRDAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPR
                     IC"
     gene            25444..27522
                     /gene="flhA"
                     /locus_tag="OPV72_001003"
     CDS             25444..27522
                     /gene="flhA"
                     /locus_tag="OPV72_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase transcriptional activator
                     FlhA"
                     /protein_id="HCR9913370.1"
                     /translation="MSYTPMSDLGQQGLFDITRTLLQQPDLASLSEALSQLVKRSALA
                     DSAGIVLWQAQSQRAQYYATRENGRPVEYEDETVLAHGPVRRILSRPDALHCNFHEFT
                     ETWPQLAASGLYPEFGHYCLLPLAAEGRIFGGCEFIRQEDRPWSEKEYDRLHTFTQIV
                     GVVAEQIQNRVNNNVDYDLLCRERDNFRILVAITNAVLSRLDINELVSEVAKEIHHYF
                     NIDAISIVLRSHRKNKLNIYSTHYLDEHHPAHEQSEVDEAGTLTERVFKSKEMLLINL
                     NERDPLAPYERMLFDTWGNQIQTLCLLPLMSGKTMLGVLKLAQCEEKVFTTANLKLLR
                     QIAERVAIAVDNALAYQEIHRLKERLVDENLALTEQLNNVDSEFGEIIGRSEAMYNVL
                     KQVEMVAQSDSTVLILGETGTSKELIARAIHNLSGRSGRRMVKMNCAAMPAGLLESDL
                     FGHERGAFTGASAQRIGRFELADKSSLFLDEVGDMPLELQPKLLRVLQEQEFERLGSN
                     KLIQTDVRLIAATNRDLKKMVADREFHNDLYYRLNVFPIQLPPLRERPEDIPLLVKAF
                     TFKIARRMGRNIDSIPAETLRTLSGMEWPGNVRELENVVERAVLLTRGNVLQLSLPDM
                     TAVTPDTSPVATESAKEGEDEYQLIIRVLKETNGVVAGPKGAAQRLGLKRTPLLSRMK
                     RLGIDKDALA"
     gene            complement(27584..27928)
                     /locus_tag="OPV72_001004"
     CDS             complement(27584..27928)
                     /locus_tag="OPV72_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrous oxide-stimulated promoter family
                     protein"
                     /protein_id="HCR9913371.1"
                     /translation="MPGKRIAREKLTIKKMIALYESQCPQASAVQGHYDALFAYAQKR
                     LDKCVFGEEKPACKQCPVHCYQPAKREEMKQIMRWAGPRMLWRHPVLTVRHLIDDKRP
                     VPELPEKYQRKK"
     gene            28110..29027
                     /gene="sitA"
                     /locus_tag="OPV72_001005"
     CDS             28110..29027
                     /gene="sitA"
                     /locus_tag="OPV72_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron/manganese ABC transporter substrate-binding
                     protein SitA"
                     /protein_id="HCR9913372.1"
                     /translation="MTNLHRLKTLLIAGIVAILALSPAYAKEKFKVITTFTVIADMAK
                     NVAGDAAEVSSITKPGAEIHEYQPTPGDIKRAQGAQLILANGLNLERWFARFYQHLSG
                     VPEVVVSTGVKPMGITEGPYNGKPNPHAWMSAENALIYVDNIRDALVKYDPDNAQIYK
                     QNAERYKAKIRQMADPLRAELEKIPADQRWLVTSEGAFSYLARDNDMKELYLWPINAD
                     QQGTPKQVRKVIDTIKKHHIPAIFSESTVSDKPARQVARESGAHYGGVLYVDSLSAAD
                     GPVPTYLDLLRVTTETIVNGINDGLRSQQ"
     gene            29024..29845
                     /gene="sitB"
                     /locus_tag="OPV72_001006"
     CDS             29024..29845
                     /gene="sitB"
                     /locus_tag="OPV72_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron/manganese ABC transporter ATP-binding
                     protein SitB"
                     /protein_id="HCR9913373.1"
                     /translation="MSQSAITVDQVTVTYRNGHTALRDATFQVPGGSIAALVGVNGSG
                     KSTLFKALMGFVHLARGDITILQQSVNQALKKNLIAYVPQSEEVDWSFPVLVEDVVMM
                     GRYGHMGWLRRPTAHDHACVDAALARVDMQEYRHRQIGELSGGQKKRVFLARAIAQDG
                     QVILLDEPFTGVDVKTEARIIDLLRELRDEGRTMLVSTHNLGSVTEFCDYTVMIKGTV
                     LASGPTETTFTAANLELAFSGVLRHIALSGGEEHIITDDERPFISRRVASGGKSS"
     gene            29842..30702
                     /gene="sitC"
                     /locus_tag="OPV72_001007"
     CDS             29842..30702
                     /gene="sitC"
                     /locus_tag="OPV72_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron/manganese ABC transporter permease subunit
                     SitC"
                     /protein_id="HCR9913374.1"
                     /translation="MNWLVEPFGYQYMLNAMWVSAMVGGLCAFLSCYLMLKGWSLIGD
                     ALSHSIVPGVAGAWMLGLPFSLGAFLSGGLAAGSMLFLNQRSRLKEDAIIGLIFSSFF
                     GVGLFMVSLNPMSVNIQTIILGNVLAIAPADITQLAIIGAVSLTILLLKWKDLMVVFF
                     DETHARSIGLNPGRLKLLFFTLLSVSTVAALQTVGAFLVICLVVTPGATAWLLTDRFP
                     RLLMIAVVIGSLTSFLGAWLSYWLDGATGGIIVVMQTLLFITAFIFAPKHGLLANRRR
                     ARLQKEPTCS"
     gene            30693..31541
                     /gene="sitD"
                     /locus_tag="OPV72_001008"
     CDS             30693..31541
                     /gene="sitD"
                     /locus_tag="OPV72_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron/manganese ABC transporter permease subunit
                     SitD"
                     /protein_id="HCR9913375.1"
                     /translation="MFLATFLEPFQFDFMVNALMVSVIVAIPCALLSVFLVLKGWALM
                     GDAMSHAVFPGVVLAYIVGIPLAIGAFIAGLFCAIATGYLDDNSRIKRDTVMGIVFSG
                     MFGAGLVLYVSIQSEVHLDHILFGDMLGVSLGDIVQTSVIALGIALIIGLKWKDLLLH
                     AFDPHQAKASGLNTTLLHYGLLCMIALTIVATLKSVGIILSISLLIAPGAIAILLTRR
                     FARALGLAVSLSVITAFAGVYLSFYLDSAPAPTIVVLFAIVFIAVFIYATWRDRRNEI
                     VPEAQG"
     gene            complement(31818..>32572)
                     /locus_tag="OPV72_001009"
     CDS             complement(31818..>32572)
                     /locus_tag="OPV72_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461787.1"
                     /note="activates Salmonella pathogenicity island 4 genes
                     and weakly represses Salmonella pathogenicity island 1
                     genes; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCR9913376.1"
                     /translation="RNVIIYGINWTNCYALQSIFKQKYPEKCVKTCNSLTALLHSLSD
                     MPDAGLILALNPHEHVYLFHALQARLQNRKVLVVADRLYYIDRCVLQYFGVMDYVLKD
                     ELSCAIRSEREKLRLPEAWLRFCHRPQKKTVAATYAFNAGETPEEVLFNINQYAWWNL
                     PPGVTQAKYALLILLSSGHPAIELAKKFGLGTKTVSIYRKKVMYRLGMDSSPLSLFRG
                     LKLDAHLQRTAFAHNPAVPDDNCALPIAVGMN"
BASE COUNT         7472 a         9181 c         8876 g         7043 t
ORIGIN      
        1 caggaagtta gcaagaaaac taaaaaccct acaggagaga acaatgatcg aaaccattac
       61 acatggtgcg gagtggttca tcgggttatt ccagaaaggc ggtgaggtgt ttaccggtat
      121 ggtgacaggt attcttccgc tactgataag cctgctggtt atcatgaatg cgctcatcaa
      181 ttttatcggc cagcagcgta ttgagcgttt tgcccaacgc tgcgccggaa atccgctatc
      241 ccgctacctg cttttaccgt ttatcgggac gtttgttttt tgtaatccga tgaccctgag
      301 tctgggacgc tttatgccgg agaagtacaa gccgagctat tacgcggcgg cctcctatag
      361 ctgtcactcc atgaacggtc tgtttccgca tatcaatccc ggcgaactgt ttgtttatct
      421 gggtatcgcc agcggactca ccacgttagg gcttcctctc ggcccgctcg cggtgagcta
      481 tctgctggta ggtctggtga cgaacttctt ccgcggttgg gtcaccgatc tcaccaccgc
      541 tatttttgag aaaaaaatgg ggattcaact tgagcagaaa gttcatctga caggagcggt
      601 atcatgacac gggttcgcat tgagaaaggt gccggcggct ggggcggccc gcttgaactg
      661 gacgttacgc caggcaaaaa gatcgtctat atcacagccg gtacgcgccc ggcgatcgtc
      721 gacaaactgg cgcaactaac aggctggcaa gcggtggacg gctttaaaga aggcgaaccg
      781 ccggaagcgg agatcggcgc ggccattatc gactgcggcg gtacgctgcg ctgcggtatc
      841 tacccgaaac gccggattcc aaccattaat attcactcga cgggtaagtc cggcccactg
      901 gcgcagtata ttgttgaaga tatttatgtc tccggcgtaa aagaagaaaa cattactcta
      961 gtcggcgaaa catctgccag accccagcct gccaaaacga cattaggacg tgactacgac
     1021 accagcaaaa aaatcaccga gcagagcgac gggctgctgg caaaagtcgg tatgggaatg
     1081 ggttctgccg tggcggtact gttccagtcc ggtcgcgaca ccattgatac ggtcctgaaa
     1141 acaattctgc cgtttatggc gttcgtttcg gcgctaatcg gcatcattat ggcctcaggt
     1201 cttggcgact ggatcgccca cggcctggcg ccattagcca gccatccact ggggctggtg
     1261 acgctggcat tgatctgctc tttcccgctg ctgtcgccct ttctcggccc aggcgcggtt
     1321 atcgctcagg ttattggcgt tctgatcggc gttcagatag gtctgggcaa tatccccccg
     1381 catctggcgc tgcccgccct gttcgcgatt aacgcgcagg cggcctgcga ctttatcccg
     1441 gtcggcctgt cactggcgga agcgaaacaa gacaccgttc gcgtcggcgt accttctgtg
     1501 ctggtcggac gcttcctgac cggcgcgccc acggtactta tcgcctggtt tgtttccggc
     1561 tttatctatc aataagaggt tcagacatga gcgtgattta tcaaaccacc atcacccgca
     1621 tcggccagag cgcgatggag gcgctcggcg aaaagatgct gattacgttt cgggaaggcg
     1681 cgccggcgga tatcgaagaa ttttgcttca tccattgtca tggcgaactg accggcgcgc
     1741 tgcagcctgg cgcgcggtgt gaactgggcc aacattgcta tccggtcacg gcggtcggca
     1801 gcgtagccga gcaaaacctg cgtgaactgg ggcatatcac cttgcgcttt gatggtctgc
     1861 gcgaagcgga atttcccggc accgtacacg ttgcggggcc tgtaccggac gatatcgcgc
     1921 cgggctgtat tttgacgttt gtcgcttaag gagaaaaaac atgaatcaag ttgccgttgt
     1981 cattggcgga ggccagaccc tgggggcatt cctttgccgt gggcttgcag aagaaggata
     2041 ccgcgtggcg gtcgttgata ttcaaagcga taaagccgcg aatgtcgccc aggaaattaa
     2101 cgccgatttt ggcgaaggta tggcctacgg ttttggcgcc gacgccacca gcgagcagag
     2161 cgtgctggcg ctgtcccgcg gcgtagacga gattttcggg cgcgtcgatc tgctggttta
     2221 cagcgcgggt atcgccaaag cggcgtttat cagcgatttc cagttgggcg attttgaccg
     2281 ctcgctacag gtgaatctgg tgggctattt cctctgcgcc cgtgagtttt cccgcctgat
     2341 gatccgcgac ggcattcagg ggcgcattat tcagattaac tctaaatccg gcaaagtggg
     2401 cagtaaacac aactccggct acagcgcggc gaaattcggc ggcgtggggt taacccagtc
     2461 tctggcgctg gacctggcgg aatacggcat taccgtacac tcgctgatgc tcggcaacct
     2521 gttgaaatcg ccgatgttcc agtcattgct gccgcaatac gccactaaac tgtgcattaa
     2581 gcccgacgag gtggaacagt attacattga taaagtaccg ctcaaacgcg ggtgtgatta
     2641 tcaggatgtg ctgaacatgc tgctatttta tgccagcccg aaagcgtctt attgcaccgg
     2701 gcagtcgatc aacgtaaccg gcggtcaagt gatgttctga ccgtgaattg ccggatggcg
     2761 ccgtaggccg gataagacgg ttacgccgcc atcaggcaaa acaacaggag cacattatgg
     2821 tttccactct gattaccgtc gccgttatcg cctggtgtgc acaactggcg ctgggcggct
     2881 ggcagatttc ccgctttaat cgggctttcg ataaacttag ccaacaggga cgggtcggcg
     2941 tcgggcgctc cggcgggcgt tttaagcccc gggtggtggt tgccgtggcg ctggacgaac
     3001 agcagcgggt gacggacact ttattgatga aaggccttac ggtattcgcc agaccggtta
     3061 aaattgccgc aatgcaagga aaacatttgc atgaattaca gcctgatgtg atctttcccc
     3121 atgattcgct cgcgcagaat gcactatcat tggcgcttaa actgaaacat gggtaatttc
     3181 gttgtgaatg cgaatagctt gcgaaattat cattttgcaa cctataccct aaataattcg
     3241 agttgcagga aggcggcgac gcagcgaatc ccctggaacg tacatcaata cgtgaccggg
     3301 gtgagcgagg aaagccaacg cacatgcagc gtgaagtatt acgggtaaat acataagtca
     3361 gggtaatcac gcctatgaaa cctcgtcagc gtcaggccgc gattctggag cacctgcaaa
     3421 aacagggaaa atgctcggtt gaagaactgg cccagtactt tgacacgaca ggcaccacta
     3481 tccgtaaaga tctggtcatt ctggaaaatg ccggaaccgt catccgcacc tatggcggcg
     3541 tggtgttgaa taaagaagag tccgatccgc ctattgatca caaaacgctt atcaacaccc
     3601 acaaaaaagc gctgatagcc gcagccgctg tgaaatatat ccatgatggc gattccatta
     3661 ttctggacgc cggaagtacc gtgttacaga tggtgccgtt gctttcgcgt tttagcaaca
     3721 tcacggtgat gaccaacagc ctccatattg ttaacgcgct atcggaactg gacaacgaac
     3781 aaactatcct gatgcccggc ggcaccttcc gtaaaaaatc ggcgtcgttt cacggtcaac
     3841 tggcggaaaa cgcctttgag caattcagct ttgataaact tttcatggga actgacggta
     3901 ttgacctgaa tgtcggtgtg accacgttca atgaggttta caccgtcagt aacgcaatgt
     3961 gcaatgcagc acgcgaggtg attctgatgg cggactcctc aaaatttggt cgtaaaagcc
     4021 ccaatgtggt gtgcagtctg gaaaccgtcg acaaactgat cacggacgcg gggatcgatc
     4081 cggcatttcg tcaggcgctg gaagcaaaag ggattgaagt aatcataacc ggagaaagca
     4141 atgagtgatg cactactaaa cgcgggccgt cagaccttaa tgctggagct acaggaagcc
     4201 agccgtctgc cggagcgtct gggcgatgat tttgtccgcg ccgccaatat cattattcac
     4261 tgtgaaggca aagtgatcgt ttccggtatt ggtaaatcag gtcatattag taaaaaaatc
     4321 gccgcgacgc ttgccagtac cggtactccc gctttttttg ttcatccggc ggaagcactg
     4381 catggcgatc tggggatgat tgaaagccgc gacgtgatgt tatttatctc ctattccggc
     4441 ggcgcaaaag aactcgacct catcatcccg cgtctggaag ataaatccgt cgcgctgctg
     4501 gcgatgaccg gtaaacctca ctctccgctg gggcgagcgg caaaagccgt tctggatatt
     4561 tccgtcgagc gtgaagcctg tccgatgcat ctggcgccga catccagtac cgtcaatacg
     4621 ctgatgatgg gcgatgcgct ggcgatggcg gtcatgcagg cgcgcggttt taacgaagaa
     4681 gatttcgccc gttcgcatcc ggctggcgca ctgggcgcgc gtttgctcaa taatgtgcat
     4741 cacctgatgc gccagggcga tgcaataccg caggtgatgc tcgccaccag cgtgatggat
     4801 gccatgctgg aacttagccg taccgggctg gggctggtgg cggtttgcga tgagcaacat
     4861 gttgtgaaag gcgtctttac cgacggcgac ctgcgtcgct ggctggtagg cggcggcgcg
     4921 ctcaccacgc cagtaagcga agccatgacg cccaacggta ttacgctcca ggcgcaaagc
     4981 cgcgccattg acgccaaaga gctcctgatg aaacgcaaaa ttaccgccgc gccagtggtc
     5041 gatgaaaacg gcaaactcac cggcgccatt aacctgcagg atttctacca ggcggggatt
     5101 atctaatcct tcagtcccag acgcttcgcc agccgatgca ggttggcgac gtcggtttcc
     5161 agcgcccgcg cactggccgc ccagttgtga ttattttgcg ccagcgcctg gcgaatcatc
     5221 tctcgctgga agttctccgt cgattcgcgc aaattgcggc aggccggcaa cgccagaaag
     5281 ctttccgcag acggcgcggg taaaacgtcc tctgacaagg caaaatgctg ctcctccagt
     5341 accacctcat cccctgcccg ggtcgctctc gccagtacaa ccgcacggtg aatggcatgt
     5401 tccagctccc ggacgttgcc cggccagcca tagttgagca aatggcggcg cgcgccggga
     5461 ctcagtacca cgcgggacag ccccagccgc agtcggcact gctcgcaaaa atagcccgcc
     5521 agcaacacca catcatcgcc gcgctcgcgc agcggcggca caaagagcgg gaaaacgctc
     5581 aggcgatgga acaggtcggc gcgaaaacgc cccgccagca cctcttcacg caggtcacgg
     5641 ttggtcgccg ccaacacccg cacatccacg cgcaggctac gatcgtcgcc gacgcgctga
     5701 atatcgccat actgcaacac gcgaagtagc ttggcctgta gcgccagcga cagttcgcca
     5761 atctcatcca gaaacagcgt accgttatcc gccatttcaa acttaccgct acgattactg
     5821 atagccccgg taaaagcccc ttttacatga ccaaacaact cgctctccgc cacgctttcc
     5881 ggcagcgcgg cgcagttgag atagaccagc ggattgaccg ctctggggga gccctggtga
     5941 atagctttcg ccaccagctc tttaccggtc cccgtttcac cgccgatcag cacgttaaga
     6001 tcggagcccg ccacaatctc gatctctttt ttcaactgcg tcatcgccgg cgacagaccg
     6061 atcatgtgcg tctcttttat cggttcaaac acgcctgacg accccggcag catgttctgg
     6121 ctttccagtt gttcaattaa cagcgcatta ctcaatgccc cggcggccag cgcggcgaca
     6181 agccgtagtt cttcatcgct aaatacctcg aactgctccg gcgtcatagc atcaagggtc
     6241 agcgcaccga tgaggttctg tccggcaaac agcggcagac caacacaggc gtggactttc
     6301 aggctttcct gtccgggaat taacccgtca tatggatcgg gtaaatcgct atcagccgga
     6361 aaacgcacca cgtcccccgc gcgggcgatg gcttccaggc gcggatgccc ttccagggta
     6421 aaacgtctgc cgaggacgtc ctgcgccagg ccatcaatcg ccagtggaat aaattgtcgt
     6481 gattcataac gcagcagcgc cgaggcgtcg cacgccagca cctgacgcag cgtagtaatc
     6541 agccgctgaa aacgatcctg atgcccaatg ccgcgttgta actcaatggc gatgcccgcc
     6601 aatacctcca cggaaaaact catggttacc tcattgtcat tttgacaatc tatagtgtca
     6661 tattgacagc atcatttata gtctttttga ctataccaaa aatacaaaat tattataatt
     6721 tcatataaat caataagatg taaagttggc acactacctg caataagcaa aacaactttt
     6781 tgcaaacgtt gaatgaattg aggtggttat gtctattctg gttaaaaata atattcattg
     6841 ggttggccaa cgcgactggg aagtacgtga ttttcacggc actgaataca aaacgctgcg
     6901 tggcagcagc tataacagct atctcattcg tgaagaaaag aatgtgctga tcgataccgt
     6961 cgatcataag tttagccgtg agtttgtgca aaatctgcgc agtgaaatcg acctcgcgga
     7021 catcgactac atcatcatta accatgccga agaagaccat gcaggcgcgc tgaccgaact
     7081 gatggcgcag atcccggaca cgcctatcta ctgtaccgcc aacgccattg actctatcaa
     7141 cggccatcac catcacccgg aatggaattt taaggtggtg aaaaccggcg atacgctgga
     7201 tatcggcgac ggcaagcagt tgatcttcgt ggaaacgccg atgctgcact ggccggacag
     7261 catgatgacc tatatgaccg gcgacgcggt gttattcagc aacgacgcct ttggtcagca
     7321 ctactgcgac gagcacctgt tcaatgatga agtggaccaa actgaactgt ttgaacaatg
     7381 ccagcgctac tacgccaata tcctgacgcc gttcagccgt ctggtaacgc caaaaattac
     7441 cgaaatcctc ggcttcaacc tgccggtgga tatgattgcc acctcacacg gcgtggtatg
     7501 gcgcgacaac ccaacgcaaa tcgtggagct gtatctgaaa tgggcggcag attatcagga
     7561 agatcgtatc actattttct acgataccat gtcgaacaat actcgcatga tggcggatgc
     7621 catcgcacag ggtatcaatg aagtggaccc caacgtggcg gtcaaaatct ttaacgtcgc
     7681 ccgcagcgat aaaaatgaaa tattgaccaa cgtcttccgt tcgaaaggcg tgctggtcgg
     7741 cacttctacc atgaacaacg tgatgatgcc gaaaatcgct ggtctggtgg aagagatgac
     7801 cggcctgcgc tttcgcaaca aacgcgccag cgccttcggt tctcatggct ggagcggcgg
     7861 cgcggtggat cgactgtcca cgcgcttaca ggatgccggt tttgaaatgt ccctgagtct
     7921 gaaagcgaaa tggcgtccgg atctggatgc gctggagttg tgccgtcagc atggtcgcga
     7981 catcgcccgt cagtgggcgc ttgctccgct gccggaaacc acacagaaaa ccgcgccagt
     8041 cgaagaaacc acaacctgca ccgccgcaga cctcggcccc aaaatgcaat gcagcgtatg
     8101 ccagtggatt tacgaccctg cgctgggcga gccgttgcag gatgtcgcgc cgggtacgcc
     8161 gtggagcgac gtgccggata acttcctgtg cccggaatgt tcattaggta aagacgtgtt
     8221 cgacgtactg gcgacggagg caaaatgagt cgggggatca tcattattgg gtcgggcttc
     8281 gccgcccgcc agctcgtcaa aaatatccgt aaacaagatg cgcatgtgcc gttaactctg
     8341 attgcggcgg acagcatgga tgagtacaac aagcccgatc tcagccacgt tatcagccag
     8401 tcgcagcgcg ccgatgatct cacccgccag ttagcggggg aatttgctga acagtttaat
     8461 ctacgactgt tcccgcatac ctgggttact gacattgatg ccgatgccca tgtggtgaaa
     8521 agtcaggata agcagtggca gtacgacaag ctggtactga cgaccggggc gacagccttt
     8581 gtgccgccga ttgcaggacg tgagttaatg cttactttga atagccagca ggagtaccgc
     8641 gcctgtgaga caccactgcg cgacgcgcag cgagtgctga ttgtcggcgg cggtctcatt
     8701 ggcagtgaat tagcaatgga tttctgccgc gccgggaaaa cggtaacgct gatggataac
     8761 gccgccagcc ttctcgcctc actgatgcca ccggaagtga gcagtcgctt acagcatcac
     8821 ctgaccgata tgggggtgca tctgctgctg aaatcgcagt tgcaaaaact ggagaaaacc
     8881 gaagccggta tccgcgctac gctggtaagc cagcatagta ttgaggtcga tgcggtgatt
     8941 gccgccaccg gcttacgccc ggagaccgct ctggcgcgcc gcgccggggt agccgtcaac
     9001 cgcggcgtct gcgtggatag ctatctacag accagtcacc cggatattta tgcgatcggc
     9061 gattgcgcgg aaatcaatgg tcaggtgctg cccttcctgc aaccgatcca gttaagcgcg
     9121 atgtacctgg cgaaaaatct gctcggcggc aacgcgccgc tgaagctacc ggcgatgctg
     9181 gtcaaagtca aaacgccgga actgccgctg catctggcgg gagaaactca gcgccgcgat
     9241 ttaagctggc agattaccgc agaatctgac ggtatgattg ccaaaggcat gagtggagaa
     9301 ggccagctac gcgcctttgt ggtgagtgaa gaccgcatga aagaggcctt tgcactgctg
     9361 aaaacgttgt cggtataagc ctgtgatgcc ggatagcgcc gcttcgcgtc ttatccggcc
     9421 tacgagtgag catctgttta cacgccggat aaggcgcagc cgccatccgg cgccctacac
     9481 ttcccttaac gctcgcgctg cggcaatcac gccctgtcca aacgacagtc cgccgtcgcc
     9541 cgccggtaac cgctgcggaa ataacaattt aaaatcagaa agataaaagg caagacgcgc
     9601 gcgcagtaag cggttgtgta tcaccccgcc gctgaagacc agagtggtta tcccccgcgc
     9661 cgtagcctgt tggcgcatta gcgtggcaaa cccgcacgcc agcgcatcat gaaaagccca
     9721 ggcgcgttgc gcgggcgtgg cctgccagtt caaccattgc cgccagaaaa cagcgacgtc
     9781 cagttgagcg ccgttaagcg gcatcgttac cggatactca acgttagcgc attgagaggc
     9841 cagcgcctcc agcgcgcagg cggcctcgcc ctcatagcta agcgatgctg gcgcgcagcg
     9901 aagcgcggca gccaccgcgt caaacaaccg cccgcaggaa gaggccaacg gggcattgac
     9961 gccgcgctca atggcgcgcg ccaggacact ccagttttgc tgttgcagcc ccgctgtctc
    10021 cgggtaattc tgccagtccg gcacaaagcg caggcactgc gctaacagat tacgccacgg
    10081 ctgtttggca gccagatcgc ctcccggcag cgccacggcg ggtaaaccgc ctaaatgttc
    10141 gcattcgcga taattgaccc gcaaacattc tccgccccat agcgcgccat tctcacccat
    10201 gccgataccg tctaccgtca gggcaatcac ctctccgccg tccagcggcc aaccatgctc
    10261 ggccaggcaa gccgccgcat gggcatgatg gtgtaacacc gtctctgtcg gcagacgcat
    10321 ctcactggcc cactgactgg aaacatagcc cggatgcgca tcacagacga tacgctctgg
    10381 cgtaaaatcg tagattgact ggatcaaacg caatgcctcg cgccactgcg cctggatacc
    10441 gtcatcgctg agatcgccta aatgttggct gacaaccgcc tgttcgccgc gtaccagaca
    10501 gaacgtgttt ttcagatccg cgcccagaca aagtatcggc ggcacatcgc gaaatccggg
    10561 cggcaacgca atcgcgtccg gcacgtatcc ccgcgaacga cgcagcattt cgccgctgtc
    10621 gcgcacgaca gagtcgtcca tgcgctgtac aatgtcgcga ttgtgcaaca gaaaaccatc
    10681 ggcaatatcg tgtaaatcgt ccagcgcctg ttcgttggtg atggcgggcg gtttgccgct
    10741 caggttgccg gatgtcatca ccagcgggta attgagtgcc tgcaacaaga gatgttgcaa
    10801 tgggttggct ggcagcatca cgcccacttc cgtaagtcct ggcgcgatgc cctcactcag
    10861 cgaaggtaca tactgcttat ccaccagtac aatcggggcc gctggcgtgg tcagcagcga
    10921 acgcgccgcg gtcggcagcg tttgcgccgt gggcaacatc accgccaatg gtttcgccgg
    10981 acgatgttta cgcgcccgca gcatcgccac tgcgttatcg ttgcgcgcgt cgcaggccag
    11041 atgaaaacca cccagccctt taacggcaat aatgcctccg gcgttcagtt gggcgaccgc
    11101 cgcctgcaaa gccgcctctt tttccgctcg ttcatgttgg ctccgccact caagatgcgg
    11161 cccgcatgac ggacaggcaa cgggctgggc atgaaaacgg cgatcgtacg gatcgcggta
    11221 ttcgctgtcg cattccggac acaagggaaa cgccgccatc accgtaaatg gccggtcata
    11281 gggcatagcg cgaataatgg tgaagcgtgg tccgcagtgg gtgcaattga tgaaaggata
    11341 acggtagcgc cgctcgcctg gggtattcat ctcggcaaga catgccgggc aggtcgccgc
    11401 atccggcacg atttgcgtgt tcatcgaacc gcctgcgctc tgacgaatgg tgaaatccgt
    11461 cggtgcgcgc tcccatacca acgacgcgtg ttcaacgctg tcaatgcgcg ccagcggcgg
    11521 gcaatcctga tagagcgcgg caataaattg cgacggatct tccagcagcc gaacgacgac
    11581 gccgtcgccg tcattacaca cgtcgccgtg taattgcaac tgctgcgcca gctgccagac
    11641 aaaaggacga aaaccgacgc cctgtacttt gccccgaatg cgtagctgta cgccggaagg
    11701 tgtgtctatc gccatcttat tttcccgcca tcatcgaacc cggatgcctg atggcgcgac
    11761 gcttatcagg cctacaaccg cacggaccgt agaccggata aggcattgat gccgccatcc
    11821 ggcaatgctt tgtggcgtat tctacgcgca atcgcagaaa tcagaaaagc agcgatgccg
    11881 ttgaatccag cgccgcacga cggcgttttt ccgcgctcag ctgttcaagc ttattgcggt
    11941 ccacgcagat gagggcgtgc gttgggcaag cggccataca ggccggaccg gcttcacggt
    12001 ggtgacacag atcgcacttg ttggcttcgg ctttttcggc acgcacgttt agccccgcgc
    12061 cgctattgcg aaccaccgga cgaaccacca cttccatggc gccgtaagga catgccacta
    12121 cgcaagtttt acagccaatg cagcgttcct gcatcacatg aacaaagcct ttgtcacggc
    12181 tgatggcacc attcgggcaa acgttggcgc acggcgcatc ttcacactgg cgacacagcg
    12241 ttgccgtgga aacgttcacg cctttgataa catggatacg aggtaaaaag gtttcagggg
    12301 tcagcgatgc gcaatcctga ttttcctgat gggatacgac gcaagccact tcacaggtac
    12361 ggcaaccaat gcacttactc gcgtctgcaa tgatgaaacg gttcatcaaa ttctccagca
    12421 ataacagatg atgtgccgat atatacacga atcgtgccaa tttttatttc attgttattt
    12481 aagaatattc tttctatttt cgtgagcatt tacgtgtcat cgtcacaagt gtcgatgaca
    12541 cgtaatgtcg ccagtggtgg tcaagatttg cagtgatagc cagccaactc tgcacagaaa
    12601 ctggcatcaa tcctgattaa cgcctggcaa tacgttaccg cgtattaaac agcgctgcgt
    12661 aagggaaaga tcgtccgttt gcggattcct tccggcaata ggtttgataa ttaatttacg
    12721 gccaggatag tgattaaagc gggtcagcgc cggataactc aaccggccaa accagccgtg
    12781 tacgcgctgc cagcgggcgt ccttcacctg atataaattg gttatccagt agcctgagtc
    12841 aaactgcata tccaacagtt gcgtgcgacc attgccctgt aaatcaagca aatcatcgac
    12901 gccagtatcg gtggcggtat aaaaccccca cggttcaaag acgcaggggc ggccattctt
    12961 gagaaaggtg aaaatgatgt attgcgcgct cggcgccagg cccaacccag gattgcccaa
    13021 ccagataacc aagtcctgaa tgccgttacg atcgaggtca gcgcgataaa attgcgcatt
    13081 acccgccaaa ttaatcagcc ttcccaccgg gacaacccac gaattaccgg ctctgtcttt
    13141 tccgctaatc cgccattcgt tatctttttt cggctccggc agtagcgtca cgctactgac
    13201 tccgacctgg cgaaaatgcc aggtctggtc gggcgataca gaataaggca ggatcaaaag
    13261 cggcttcagc gcacgctttt gcgcatattc accgtcgctc atcggcaggt aaccgacaac
    13321 accggtagcc agtgcgcgtg cggcgaggca gagaaatagc agtccgctcc atacgataat
    13381 cttcacgttc ttcttaccgc ctatgccggg taacacaaat ccatccagaa tgagtacgca
    13441 ttttacgcct ccggcgcgtc cagcgcggca aatccgccgt ttccctgcca gccttccagg
    13501 cgctgataga cgatgtttac cgcgtcctta atcggttgag tcatcggata ataaaacccg
    13561 acgatatccg gctggatacc aacaaaaatc acctcgccga catcctcttt cagcagatcg
    13621 ataaggtagt tcagcggcat attgtgggtg gtcatcataa acatttcggc gatatcatcc
    13681 ggatcgatga tgcggatctc gcccggatta agtcccatat cggtggcgtc gacaatcaac
    13741 agacgctgcg ggcgcagttc gcgaatcgcc acaatgtcgt tttccggcgc gctgccgcca
    13801 tcgatgacaa cccagttgcc cttcggctgc gccgcgcaca tttccgccag taatgggcct
    13861 gcgccgtcgt cgcccatcat gctgttgccg acacagagta aaacgtcagt cacgaagcct
    13921 cctcaccatc aggtagatgg cgctttcctg atgaatgtca tgcagcatac tgagcatcag
    13981 tttgctccat tcttgctgct gcggggtctg cgcggcgcgc gcctcatcaa acgcgcgcgc
    14041 cagcatttgc acatggttga aatcgatgac gatctcgcca tacttcggca cgccttccat
    14101 tttacgccgg gcatcgctac cggcttccag ggtggcgatc cacgccagat actcatccca
    14161 tgggcaggtg agcgcggcct ccaggcaatc gataaccccc aggtggtgac caatcgccag
    14221 gctgtaatag acaacctgct gcgcctcggc gggcgtcgca tcgttctcat caataaactt
    14281 acggctcagt tgactgaaca ccacctgttc gctcatcgga tacgcgcctc ttcaacaaca
    14341 tgattgagat ggatgacaat ttcggttaaa cgcggatcgt tttccgcttc cagccaacgc
    14401 gccacttgct gctcgccctg ccccaactgt gtcaggtaat catcggcgat ctgacgacca
    14461 tagcgataac ccgccagccg gcacgccgcg cgatccacct tcacgcgcag cggctgcacc
    14521 atatccggat gcaggatctc tgcgggctga tcgtccagct cacccggcgc gcgggcgtgg
    14581 attttctgct ccagcaggcc aagcgccatt gcaaagccat acagcgtggc ggcaggcgtt
    14641 ggcgggcagc ctggaatgta cacatccacc gggacgattt tgtcggtacc gccccagacg
    14701 cagtacagat catggaagat gccgccgctg ttgccgcagg cgccgtaaga gatacaaatt
    14761 ttcgggtccg gcgccgactg ccaggcgcgc agcgccggag agcgcatggc gcgggtcacc
    14821 gcgccggtaa acagcagaat atcggcatga cgcggcgacg gtactacttt gatgccgaaa
    14881 cgctcggcat caaacagcgg cgaaagcgtc gcaaagattt cgatttcaca gccgttacag
    14941 ccgccgcagt ccacgcggta aacgtatgcc gaacgcttaa tatttttcag tagagacgcc
    15001 ttcatgctgg cgatggattc atccaccgtc atcggtaccg gaatgccgtt ggcgtcacgc
    15061 gggcctaata aattgctcat tagctgacct ctttcatatg gcgagtcagt tcaatacggt
    15121 cggacggcac caggcatttc tgacgcttac agtccgggca ggtctcaaag ctttcgcggt
    15181 ggttttctgc tcggctgtcg ccgttgtgcg caagcagcgc aatggcgtag tcgatctctt
    15241 tctgtaccgc gaaaggacga ttgcacacgc ggcagttgca cagcgcgaag cgggactgtt
    15301 gcaggaagtc ttctttcttc cacactgcca gttcgtactc ttgcgacagt ttgatcgccg
    15361 ccgtcgggca cacctcttcg cagcgaccgc agaagatgca gcggccaaga ttgaactgcc
    15421 acgccagctc attggtcgca agatcggttt ccaccgtcag cgcgttcgac gggcaggcat
    15481 taacgcaggc ggcgcagccg atgcactgct gcggattatg ttccggcttg ccgcggaagt
    15541 ttttatcaac cgcaatcggc tccagcggat aagacgaggt cgccgtgccg gttttgataa
    15601 cttttttgat aaaggtaaac atggcgattc cttatttcag cggcgagttt ttacgctcaa
    15661 tgctgtagcg ctcaagttct ttgtacggca cgactttgct cttcttctta cgtacatcga
    15721 ccacggtcat ccggtcggta caggagtagc aaggatcgag gctaccgatg atcagcggcg
    15781 cgtcggagac ggtgttgcca cgcagcatat aacgcagggt cggccagttg gcgtaggttg
    15841 ccgcacggca gcgccagcgg taaagcttct ggttgtcgcc ggtcatgctc cagtggatat
    15901 cgtcaccacg cggcgcttca gcgaagccga gcgcaaaacg gtgcggaata taggtaaagc
    15961 cttccaccat cagcgggccg cccggtagat tatccagacc gaaatcgatc atattcagcg
    16021 aggtgtagac ttcgttgata cggactttca gacgagaaat cacgtcgcag ccctgctcgc
    16081 tatgtacttc catcggcagc agaccgtagc cgacaaacgg gtggtcggcg cgggtgtcgc
    16141 gggcgtgacc gctggcgcgc accatcgggc cgacattact gaagtcgcgg gcaatttccg
    16201 ggtccagacg gccgataccc acggtacgct gttccatatt cggcgtgctc agcagcatgt
    16261 ccaccagctc ctgcacgtca cgacgcatct gctgcgccag ttgacgggtc tggatcatgt
    16321 cctctttgag cagatcgcgg cgaatcccgc cgatcaggtt cagaccgtaa gttttgcgcg
    16381 ccccggtcag tatttccgcc atcttcatgg aggtttcacg cacgcggaag aactgcataa
    16441 agccggagtc aaagccggta aagtggcagg cgaggcctag gttcagcagg tgcgagtgca
    16501 gacgctccac ttccagcaga atggcgcgga tcatctgcgc acgctccggc acctgaatgc
    16561 ccatcgcgtt ttccacggaa gtggtgtagg cagtgctgtg cgcgaaaccg cagattccac
    16621 acacgcgatc cgacaggaag gtgacttcgt tataacccat gcgggtttcc gccagttttt
    16681 ccataccacg gtggacgtag aacaggcggt agtcggcatc gataatgttt tcgccatcga
    16741 cgaacagacg gaagtggccc ggttcatcgg aagtgacatg cagcgggcca atcggcacca
    16801 cgttattttt cttgtcaccc agctcgttaa tgaactcgta ggtttccgca tcggtggtcg
    16861 gcgccgggcg ctgacgataa tccatgctgt ctttacgcag cggatagagt tcatccggcc
    16921 agtcgtccgg cagcaccaga cggcgctcgt ccggcagacc gaccgggatt aaaccgtaca
    16981 tgtcgcgtac ttcgcgctca ccccacacgg cagccggcac gcgcggcgta acggatggga
    17041 attccagctt attggcatcc acttcaacac ggacggtaat ccagcacttg gtgccctgct
    17101 ccatcgacag cacgtaataa acggcatagt ggccgcacaa ctggcgttcg tcattaccga
    17161 acagcaccga cagccaccca ccctgctggt agtaaagaaa ctccaccact tccggcagat
    17221 agttcacttt taccgtaata gtcagctgat ctttggtctg ccaggcttcg tccatcacga
    17281 cgcccggaaa cgcctggtgc agcgccgcaa ggtattgttg acctaatttt tcttcaaaca
    17341 tgctcaaact ctcttaaatc acgccgccag caaggagacg aaggctaaaa acgcaaaccc
    17401 aaaaccggcc caggtcacgc gtgaagtggc gcaaaaacgc agtcgcgcca tgctgttttc
    17461 aaacagggcg atcaccagta cgccgacaat cagcttgacg acggcaatca ccagcgccag
    17521 taacagtccg cctgcgctga aggtttccat ctgtccccac ggcaaaaaca cgccgacgaa
    17581 catttgcagc accaccagtt gtttcaggct gatgccccat ttcagcaccg caaagccgct
    17641 accgctgtat tcggtcaacg gcccttcctg caactcctgc tccgcttccg ccaggtcgaa
    17701 cggcagcttg cccatttcga taaaggtggc aaaggcgcag gcgcacagcg ccagaatcag
    17761 cggaatactg cgcgcgacag gccagtgata aatggtatcg gcgatattgc tgatatgagt
    17821 tgaacccgcc acctgcgcgg ctacccacag acccagcagc agaatcggct ccaccagcac
    17881 gccgagcatc gcttcacggc tggcgccgat cgcagtgaac ggactgccgg tatccaggcc
    17941 tgcaatagag aagaagaagc gcgcaatcgc gaacagataa atcagggtga ttaaatcacc
    18001 cagttgcggc aacggagatc caacggtgac gaccggcagc gcggtggcga tagtcagcat
    18061 cacgccgacc atcacaaacg gcgtcaggcg aaaaacccag ccggaatcag cgggcgcaat
    18121 actctgacga ccgagcagtt tgataatgtc gcggtactcc tgcaacacgc ccggcccacg
    18181 gcgattgtgt agacgggcgc gcgccacgcg agtaataccg gacagcaatg gcgcaacggc
    18241 aaatagcacc agcgcctgaa ttaacggata aaacacactc attttcaggc tcctcgtgaa
    18301 accacaatca ccaccagcac cgccagctca atcagcgcca gacgacggaa cagccccgcg
    18361 gccgccgcgt tctgccagcc cggcaccagc gataccgggt tcagccattt acgcagtttg
    18421 agtaccgggg caaaggcctc tttcaccggc atggcgaaac cgtgcgcggt aatcaccatc
    18481 gactgctcat ggtcgtagcc gcacacccag gccgcgccgc gagaacgcga cggcagacgg
    18541 ttgcctttga acatcgccat aatgatgaat ggcagtagcg gacaggcgac caacagcagc
    18601 gtgatcatcg gctgcgatac ggtggtgtgc gcggtttcca gcggcaacgg taccgcagtg
    18661 gaaatcatcg gcagcagcca cggcgcggca accccgccca gtacgcagca aaccgccaat
    18721 gccaccacgc tgacgcccat caggatcggc gcgcagctgg cattttcagc ttccttcgtg
    18781 cgcggcgcgc caaggaacgt cacgccgtaa actttcgcca tacacatcac cgccagcgcg
    18841 ccggtaatcg ccaggccaac cgccagcagc ggtcctaaca gacgaccaac aaacgcgccg
    18901 ctgttgccca gtttgaagaa ggactggtaa atcacccact cgccggcaaa gccgttcagc
    18961 ggcggcagcg ccgccatcgc catcagaccg accagcatgg cgatagaaat aaccggcatc
    19021 cgtttaccaa taccgcccag tttttcgatg tcgcgatgac cggtacggaa ccagatgctg
    19081 cccgcgccca gtaacagcac gcttttgaac aggctatggt tcagcagatg atagagcccg
    19141 ccggtcagac ccagcgcgat cagtaccggc tgattgagag caatcccggt aacgcctgcg
    19201 cccagaccga gcaaaatgat gccgatattt tccagcgtgt gataggccag caggcgctga
    19261 atgttatgct ccatcagcgc gtacagaccg ccgacaaagg cggtgatcat cccaagcacc
    19321 aacagcgcca cgccccacca cagtggcgca ttgccgccaa gcagagatag cgagagaatg
    19381 cccagcagcc cgattttcat caccacggtc gagaacagcg cggcggcggg agcgctggcg
    19441 ttggcgtgcg cctgcggcac ccaaccgtgt agcgggataa tcccggccag cagaccaaaa
    19501 ccgataacgc cgagcagcca gatatcggag cccagcggca gttgctgagc gcgttgatcc
    19561 agcagcccca gatccagcgt gccgtagcgc tgccacacca gccagcaggc gattgccagc
    19621 agcagcgtac cgagacggcc cagcgcaaac cacagtttgc cctctttgct accgccggta
    19681 aggaacacgg cgcagagcgc catgatttca gccatcacca ccatcgtccc cagattactg
    19741 gcgaccacag cgcagacggc tgccgccatc agcaggttga tcaacagtcc gttggctttt
    19801 acctgtggat ggcgatgcca gtcgatattg aacaggctga cgaacagacc gcacagcccc
    19861 agcgtaatca gccagatagc attcagcggc gtaatttgca gcatgtgacc ggtaaacggc
    19921 atcacgccgc taaccgtaac ggcgctggtc agcgcggtga accccgcgcc tgccgtacac
    19981 aggctgccga ccgcgccgcc gataccggca atccagccgc tcagcgcttt atgaaacgaa
    20041 aacagaaacg ccagaacggc ggcggcggca aaccacgcga cgccgctagt aatcagtgaa
    20101 agtgaactca ttatgcatcc ccactctgag cctgctgaaa caaggtgaga tcgccaaaat
    20161 cggtattaaa cgtcagctca cgtttacgtt tgctggcgcg ggcgatatcc gtgttctcca
    20221 ccaggtgtag cgctttagtc gggcacatcc gcacacaggc cgggccttgc tcgtcaaagc
    20281 tgcacaggtc gcatttcacc gcgatagcgc gcacgcccgg cacccagtcg agcaacgtac
    20341 tgacgcgcgc aggcgctggc ggcgcgggcg gcgctttcgg cgtattggcg ttcgccggaa
    20401 tatgcagcgg acggctgccg gaaaactcaa tagcgccaaa cggacaggca ataccgcaca
    20461 gtttgcagct cacgcacagg ctttcattaa gctggacagc gccgtcaacg cgattaatcg
    20521 cgttaaccgg gcataccgtg gcgcatggcg catcttcaca gtggtgacag agctgcggcg
    20581 cagattcttt ttcattcagc atcactttca ggcgcggcat tgactgcagg ccatgctggc
    20641 gatgcgtctc tgaacaggcg gcctcacagg tgtggcagcc gatacagaga gtggagtcag
    20701 caattacaaa acgattcacc aggcattcct caggtgattg tcatttttga cgaaaacatg
    20761 ccgttgaaat gtcattttcg acacttatcg acacgcccat ccccaaaaca ttcatgacat
    20821 ggcgcaacgc cacatcgcga atcaaagcgg gcaacgcctc aggcttatac agccgggctg
    20881 tgtcccttta ccaattggcg caaattaacc ggcgagttgg tttctacagc ggtatagagg
    20941 ctgtcgtaaa cgctggcgat tttttccaga tagtgctcca gcacctgctc gcgatcgcgg
    21001 ttgttaaccc gttcgtcaac cttgccgtcg atatcgagct gcgcctgtgc aatcaattgc
    21061 ttatcttcgc catctttggt ttcaacgtag tactcaatgg tgtggctgtt aaaaccatcc
    21121 gccaacgcaa cgtaaatacg aaagtgctca aacaggacaa agcaaagatc cctttccggc
    21181 gcgcagctca ttgcgtgatg caggcgcgct ttcgagaggg tgatcccctg aaccagcgag
    21241 ttgcagtaaa tatgccactg gtcctgtagg cgacgatgcc gttgcgcgat gtaatcggcc
    21301 ttttcgctta tttcccaaat agtcatgtca ggttacccgt ttaacagaga tgcctgcgtt
    21361 aagcattttc catgccaatt tttaacttat tgtttttaat ggaagacgcg cacagttact
    21421 gccgtttcga cgcggtgacg acatgtcatt tcgtcatcgt cgacattaac ctgccagggg
    21481 atacaaatat tggcataaat attgctttac aggggcaacc actacgggag gcgatatgca
    21541 cgaaatcacc ctctgccaac gggcactgga attgattgaa caacaggctt cagcatacgg
    21601 tgcaaaacgt gtgacagccg tctggatcaa aattggcgca ttttcttgcg tggaaaccag
    21661 cgctctttcc ttttgttttg atctggtatg ccgcggcacg atagcagaag gttgtaaact
    21721 gcacctcgaa gaacaggaag ccgaatgctg gtgtgagcat tgtcaacaat atgtcacgtt
    21781 gttaacccac cgtgtacgtc gttgtccgca atgtcatagc gatacgctgc gaattgtggc
    21841 cgatgacggc ttacaaattc ggcgcataga gattgatgaa actgaagatt aatgccggat
    21901 aagacgctcg cgtcgccatc cggcagaaag cctgtaacaa gaagaagatc aggagtaagc
    21961 gatgtgtacg acttgcggtt gcgctgaagg caacctttat atagaaggcg atgaacataa
    22021 tccgcactca gcgtttcgta gcgcgccctt tgccccagcg gctcgcccgg cgctgaatat
    22081 taccggcatt aaaacgcctg actttacccc aagtcagacc gcagaaggcg atctgcatta
    22141 cggccacggc gaagccggaa cccacgcgcc tggtatgagt cagcggcgga tgctggaggt
    22201 tgaaatcgac gtgctggaca aaaataatcg tctggctgag cgcaaccgcg cccgtttcgc
    22261 cgcccgccag caactggtgc tcaacctggt gtccagcccc gggtccggta aaaccactct
    22321 gctgaccgaa acgctgatga aattgaaaga ccgtgtaccg tgcgcggtga ttgaaggcga
    22381 ccagcagaca gtgaacgacg ccgcccgcat ccgcgctacc ggcacgcccg ccattcaggt
    22441 caacaccggt aaaggctgcc atcttgacgc gcaaatgatc gccgacgccg cgccgcgcct
    22501 gccgctggat gaccacggta ttctgtttat cgaaaacgtc ggaaatcttg tctgcccggc
    22561 cagcttcgat ctgggcgaaa agcataaagt cgcagtgctt tccgtgaccg aaggtgaaga
    22621 taagccgctg aagtatcccc atatgtttgc cgcggcgtcg ctcatgctgc tcaataaagt
    22681 cgatctgctg ccctacctca attttgacgt tgagaagtgc atcgccagcg cgcgtgaagt
    22741 gaacccggag attgaaatta tcctgatttc cgccaccagc ggcgaaggca tggatcagtg
    22801 gctggcctgg ctggaggcgc agcgatgtgc ataggcgttc cgggtcaaat ccgcgccatt
    22861 gacggcaatc aggcaaaagt tgacgtctgc ggcattcagc gcgacgtcga tctcacatta
    22921 gtcggcagtt gtgatgaaaa cggtcagccg cgtctgggtc agtgggtgct ggttcatgtc
    22981 ggattcgcca tgagcgtcat taacgaagcg gaagcgcgcg acacgctcga cgcgctacaa
    23041 aatatgtttg atgttgagcc ggacgtcggc gcactgctgt atggtgagga gagataatgc
    23101 gttttgttga cgagtaccgt gcgccggaac aggtaatgca gctcattgaa cacctgcgtg
    23161 aacgcgccgc ccttcttcct tacactgctg aacgaccgct gcgcattatg gaagtctgcg
    23221 ggggtcatac ccacgcgatt tttaaatttg gtctcgatca gttactgccc gaaaacgtgg
    23281 agtttattca cggccccggt tgtccggtct gcgtgctgcc aatgggacgc atcgacagtt
    23341 gcgtggaaat cgccagccat ccggaggtga ttttctgcac ctttggcgat gccatgcgcg
    23401 tgccggggaa acagggttct ctgttgcagg ctaaagcgcg cggcgcggat gtgcgtattg
    23461 tttattctcc gatggacgcg ctgaagctgg cgcaggataa cccgacccgc aaagtggtat
    23521 ttttcgggct gggctttgaa accaccatgc cgaccaccgc catcacgcta cagcaggcaa
    23581 aacagcgtga cgtgcgaaac ttctactttt tctgccagca cattacactg atcccgacgc
    23641 tgcgtagcct actggagcag ccggacaacg gcattgacgc ctttcttgcg ccaggccacg
    23701 tcagcatggt catcggcacc gaggcgtacc agtttatcgc cgccgatttt catcgcccgc
    23761 tggtggtggc tggattcgaa ccgcttgatc tactgcaagg cgtggtcatg ctggttgagc
    23821 agaaaatagc ggccctaagc caggttgaaa accaataccg tcgcgtggtg ccggatgccg
    23881 gaaacatgct ggcgcagcag gccatcgccg atgtgttctg cgttaatggc gacagcgagt
    23941 ggcgcggcct gggcgtgatt gaatcctccg gcgtccacct gacgccggag tatcagcgct
    24001 ttgacgccga agcgcatttc cgcccagcgc cacagcaggt ctatgacgat ccgcgcgccc
    24061 gctgcggcga agtgctgacc ggcagatgca agccgcatca gtgcccgcta tttggtaaaa
    24121 catgtaatcc agagaccgcg ttcggcgcgc tgatggtctc ttccgaaggc gcatgcgccg
    24181 cctggtatca gtatcgtcag caggagtgtg aagtttgaac aatatacaac tcgcccacgg
    24241 cagcggcggc caggctatgc aacagttgat taatagcctg tttatggagg cctttgccaa
    24301 cccgtggctg gcggaacaag aagatcaggc gcgtctggag ctggcgcaac tgacggcgga
    24361 gggcgaccgt ctggcgtttt ctaccgatag ctatgtgatc gatccgctct ttttccccgg
    24421 cggcaatatc ggcaaactgg cgatttgcgg tacggcgaac gacgttgcgg tgagcggcgc
    24481 gatcccccgc tatctctcct gcggctttat ccttgaagaa gggctgccga tggagacgtt
    24541 aaaaagcgtg gtcaatagca tggcggcgac cgcacgggaa gcgggtatcg ccattgtaac
    24601 cggcgacacc aaagttgtgc agcgcggcgc ggcggataaa ttgtttatca acactgccgg
    24661 catgggggcg attcccgccg atattcactg gggcgcgcaa acgctgagcg ttggcgatgt
    24721 gctgttagtc agcggtacgc ttggcgatca cggcgccact atcctcaacc tgcgtgagca
    24781 actgggactg gatggcgagc tggcgagcga ctgcgcagta ttaacgccgc ttattcagac
    24841 gttgcgtcat attgacggag tgaaggcatt gcgtgacgcc acgcgcggcg gcgtgaatgc
    24901 ggtcgcccat gagtttgcgg cgtcctgcgg ttacggtatt gaattgtccg aatccgcact
    24961 gccgctcaaa cctgccgtgc gcggcgtctg cgagctgttg gggctggatg ccctgaactt
    25021 tgccaacgaa ggaaaactgg tgattgccgt tgaacggcag gccgcagatc gggcgttggc
    25081 ggcattacgc gcgcatccgc tgggacgtga tgcggcgctg attggcgaag tcgtggaacg
    25141 caaaggcgtt cgcttagccg gactctatgg cgtgaagcga acccttgatt tgccacacgc
    25201 cgaaccatta cctcgtatat gctagcagcc tgttggcagc atactgtagg ccggataaga
    25261 cgcatttgcg gcgagatccg gcattaacgc tgcattaacg cctgatggcg ctttgcttat
    25321 caggcctacg gagtgtgtga ccagcgagtt tgcggtcagc catccggcaa taacttacga
    25381 cttataccta taattcattt accgttttcg caccgttttg cggtattttc ctggaaaagc
    25441 aacatgtcgt atacacccat gagcgatctt ggacagcaag gcttgttcga tatcactcgt
    25501 accttattgc agcagcccga tttggcgtcg ctcagtgaag cgctttcgca actggtaaag
    25561 cgttcagcgc tcgccgacag cgccggcatt gtgctatggc aggcgcagtc gcaacgcgca
    25621 caatattatg cgacgcgaga aaatggccgt cctgttgaat atgaagatga aaccgtactg
    25681 gcgcacggcc cggtacgtcg catcctttct cgccccgatg cattgcactg taatttccat
    25741 gagtttaccg aaacctggcc gcagcttgcc gcgagcggcc tctaccctga atttggtcat
    25801 tactgtctgc ttcctttagc cgcggagggc cgtattttcg gcggctgcga attcatccgt
    25861 caggaagatc gcccctggag tgaaaaggaa tatgaccgtc tgcatacgtt tacccaaatt
    25921 gtcggcgtgg tcgccgagca aattcaaaac cgggtaaaca ataatgtcga ttatgatctg
    25981 ttgtgccgcg aacgcgataa cttccgtatt ctggttgcga ttaccaacgc cgtcctgtcg
    26041 cgtctggata ttaatgagct ggtaagcgaa gtcgcaaaag agatccacca ctatttcaat
    26101 atcgacgcga tcagcatcgt gttgcgcagc catcgcaaaa ataagctgaa tatctactcc
    26161 actcactacc ttgatgagca tcatccggcg cacgaacaga gcgaagtcga cgaagccggc
    26221 acgctcacgg agcgcgtctt taaaagtaaa gagatgctgc ttatcaacct caacgaacgc
    26281 gatccgcttg ccccctacga acgaatgctg ttcgatacct ggggcaatca gatccagacg
    26341 ctttgcctgc tgccgttgat gtccggcaag acgatgcttg gcgtgctcaa actggcccag
    26401 tgcgaagaaa aagtgtttac caccgccaac ctcaagctgc tacgtcagat tgccgaacgg
    26461 gtagccattg ccgtggataa tgcgctggcc tatcaggaaa tccaccgtct gaaggaacgc
    26521 ctggtcgacg aaaatctggc gctcacggag cagcttaata acgtcgacag cgagtttggc
    26581 gagatcatcg ggcgcagcga agcgatgtac aacgtgctaa agcaggttga gatggtggcg
    26641 cagagcgaca gtaccgtgct gattctgggc gaaacgggaa ccagtaaaga gttgattgcc
    26701 cgcgccattc acaacctgag cggacgtagc gggcgcagaa tggtaaagat gaactgcgcc
    26761 gcgatgccgg cggggctgct ggaaagcgat ctgtttggtc atgagcgcgg cgcgtttacc
    26821 ggcgccagcg cgcagcggat tggccgtttc gagctggcgg ataaaagctc gctgtttctg
    26881 gatgaagtgg gcgacatgcc gctggagcta cagcctaagc tgctgcgcgt ccttcaggag
    26941 caagagtttg aacgtctcgg cagcaataaa ctgatccaga ccgacgtgcg gctgatcgcc
    27001 gcgactaacc gcgatctgaa aaaaatggtc gccgatcgcg aattccataa cgatctctac
    27061 tatcggctga atgtttttcc gattcagctt cctccgttac gcgaacgtcc ggaagatatt
    27121 ccactgctgg tcaaagcgtt taccttcaaa atcgcccgcc gaatggggcg taatatcgac
    27181 agcattcccg ccgaaacgct gcgcacgctc agcggtatgg aatggccggg gaacgttcgc
    27241 gaactggaga atgtcgtcga gcgcgccgtg ctgctgacgc gcggcaatgt gctacaactg
    27301 tcgctgccgg atatgactgc cgtaacgccc gatacctcgc ctgttgcgac tgaaagcgcc
    27361 aaagaaggcg aagatgaata tcagcttatt atacgcgtgc tgaaagagac caatggcgta
    27421 gtggctggac caaaaggcgc ggcgcagcgt ctggggctta aacgaacccc cctgctgtcg
    27481 cgtatgaagc gattgggtat tgataaagac gcgttagcgt aacgggttgc cggatctgat
    27541 ccggcctgga gatgatgcgc gccgtaggcc tggcgcttcc ccttcacttc ttgcgctgat
    27601 atttttccgg caattctgga acggggcgct tatcgtcgat aaggtgccgc acggtcagga
    27661 caggatgccg ccaaagcatt cgcggacctg cccaacgcat aatctgcttc atctcctcgc
    27721 gtttagccgg ctgatagcag tgcaccgggc actgcttaca ggcgggtttt tcctcgccaa
    27781 atacgcattt atcaagacgt ttttgcgcgt aggcgaacag cgcgtcgtaa tgcccctgca
    27841 ccgctgacgc ctgtggacac tggctttcat acagcgcgat catttttttg atcgtcagtt
    27901 tttcacgagc gatacgttta ccaggcatcg tgctctctcc gaacattaag atgcatttat
    27961 tttacacctt atccctcttt agcactatca ctgcatatcg tcgccattac gcaaataaga
    28021 attattttca tttattcatg ccttgtgcta tataacatag caaaggctat attcgatgat
    28081 taattaacca cattgttgcg agggatacta tgacgaatct acatcgtcta aaaacactcc
    28141 tgattgccgg tattgtcgcg atactcgcgc tatcgccagc ctatgcaaaa gagaaattta
    28201 aagtcatcac cacgtttacc gttattgccg acatggcgaa aaacgtggcg ggcgacgcag
    28261 cggaagtcag ctcgattacc aagcccggcg ctgaaatcca tgagtatcag ccaacgcccg
    28321 gcgatattaa acgagcgcag ggggcacagc ttatcctcgc gaatggtctg aacctggagc
    28381 gatggttcgc ccgcttttat cagcaccttt ccggtgtacc ggaagtcgtc gtctccaccg
    28441 gcgtcaaacc gatgggcatt accgaaggcc cgtataacgg taaaccgaac ccgcacgcct
    28501 ggatgtcggc agaaaacgcg ctgatttatg tcgataacat tcgcgacgcc ctggtgaagt
    28561 acgatccgga taatgcgcag atctataagc aaaatgccga acgctataaa gcgaaaattc
    28621 gccagatggc cgatccgttg cgtgccgagc tggaaaaaat tcccgccgat cagcgctggc
    28681 tggtcaccag tgaaggcgcg ttctcttacc tggcgcgcga taacgacatg aaagagcttt
    28741 atctctggcc aattaacgcc gatcaacagg ggacgccaaa acaggtgcgt aaagtgattg
    28801 ataccattaa aaagcaccat attcccgcca tctttagcga gagtacggtt tccgataaac
    28861 ccgcccgcca ggtcgcgcgt gaatccggcg cgcattatgg cggcgtactg tatgtcgatt
    28921 ctctgagcgc cgctgacggc cctgtgccaa cctatctgga tctgctgcgc gtcacgaccg
    28981 aaaccatcgt caacggcatt aacgacggac tgaggagtca acaatgagtc aatctgcgat
    29041 taccgttgat caagtcacgg tgacgtatcg caacggtcat accgccctac gggacgctac
    29101 ttttcaggtg cctggcggtt caatcgccgc gctggtaggc gtaaatggtt ccggtaagtc
    29161 tacgttattt aaagcgttaa tgggctttgt gcatcttgcg cggggcgata tcactatcct
    29221 gcaacagtca gtcaaccagg cgctgaaaaa aaacctcatt gcttatgttc cacaatcgga
    29281 agaagtggac tggtcatttc cggtactggt agaagatgtg gtgatgatgg gacgctacgg
    29341 tcatatgggc tggctacgcc gtcccacagc gcatgatcac gcctgtgttg acgccgcgct
    29401 ggcgcgggtg gatatgcagg aatatcgtca caggcagatt ggcgagctgt ccggcgggca
    29461 gaaaaaacgt gtgtttcttg ccagggccat cgctcaggat ggacaggtaa tcctgctgga
    29521 tgaacctttt accggcgtgg atgtaaaaac cgaagcgcga atcatcgatc tactgcggga
    29581 actgcgcgat gaaggccgca cgatgctggt ctcaacgcat aatctcggct ccgtcaccga
    29641 attttgcgac tatacggtaa tgattaaagg aaccgtactg gccagcggcc ctaccgaaac
    29701 cacgtttacc gccgcgaatc tggaactggc gtttagcggc gttctacgtc atatcgcgct
    29761 aagcggaggt gaagagcaca tcatcaccga tgacgagcgc ccctttattt cccgacgcgt
    29821 ggccagcgga ggaaaatcgt catgaactgg cttgttgagc cgtttggcta ccagtatatg
    29881 ctcaacgcga tgtgggtctc cgcgatggtg ggcggtcttt gcgcgtttct ctcctgctat
    29941 ttgatgctca aaggctggtc gctcattggc gatgcgctat ctcactctat tgtgcctggc
    30001 gtcgctggcg cctggatgtt agggctgccc ttctcgctcg gcgcgtttct ttccggcgga
    30061 ctggcggcag gcagtatgct ctttcttaac caacgctcac gcctgaaaga agacgcgatt
    30121 atcgggctta tcttctcctc tttttttggc gtcggccttt ttatggtgtc gctcaatccg
    30181 atgtcggtga atatccagac gattattctc ggcaacgtgc tggcgatcgc gccagcggat
    30241 attacgcaac tggcgattat cggcgcagtc tcgctgacga ttctgctgtt aaagtggaaa
    30301 gatctgatgg tcgtcttttt cgatgagacc catgcgcgtt ctatcgggct taatccgggt
    30361 cgactaaaat tgttgttttt cactctattg tccgtctcta ccgtggcggc cctgcaaacc
    30421 gttggggcgt tcctggtgat ctgtctcgtc gtcacgccgg gcgcgacggc ctggttactc
    30481 accgaccgtt ttccacgtct gctcatgatt gccgtcgtga ttggcagcct gaccagtttt
    30541 ctgggcgcat ggcttagcta ctggctggat ggcgccactg gcggaattat tgtcgtcatg
    30601 caaaccttac tgttcatcac ggcctttatt ttcgccccga aacacggtct gttagccaac
    30661 cgtcgacgcg cccgcctgca gaaggagccg acatgttctt agcaacgttc ctggaaccct
    30721 ttcagtttga ttttatggtg aacgccctta tggtttcggt cattgtggcg attccctgcg
    30781 ccttgctgtc cgtgttttta gtgttaaaag gctgggcgtt aatgggcgac gcaatgagtc
    30841 atgcggtatt ccccggggtc gtgctggcat atattgtggg gattcccctg gcgattggcg
    30901 ctttcattgc cggattattt tgcgctatcg ccaccggtta tctggacgat aacagccgca
    30961 tcaaacgtga tacggtgatg ggcatcgtct tttccgggat gtttggcgca ggtctggtgc
    31021 tctatgtttc tattcaatcg gaagtgcatc tggatcacat cctgtttggg gatatgctgg
    31081 gcgtatcgct gggggatatc gtacaaacgt cggttattgc actgggtatt gcgttaatca
    31141 tagggctgaa atggaaagat ctcctgctac acgcttttga cccgcaccag gcgaaagcca
    31201 gcgggctgaa tacgacgcta ctgcattatg gcctgctatg tatgattgcg ctgactatcg
    31261 tcgccacgct gaaatcggtg ggcattattc tgtcgatttc attgcttatc gcccccggcg
    31321 caattgccat tttgctgacg cgacgctttg cgcgcgcgct gggattagcg gtgagtctgt
    31381 cagttattac cgcttttgcg ggcgtctatc tgtcttttta tcttgatagc gcgccagcgc
    31441 cgaccatcgt ggtattattt gccatcgtgt ttattgcggt atttatttac gcaacatggc
    31501 gcgacaggcg taatgaaatc gtaccagagg cgcaaggtta acagcagcgt tcagaaaata
    31561 aatacgacag ttgtagtaga aagccaccct atatctgttg ttggtcagta tggtaagcag
    31621 ctatctttaa atttctttac aacaagcgta aagataagct gctttactcc ccatgttttt
    31681 cctgtttcga aattttttca gagtttggct aacccagcat aatgtgatta ttactcacaa
    31741 gatctgtaat atcccagcaa aaaataaatt tataactaca cgtaatacaa gagagtgatt
    31801 gtcacataaa aaatagttta attcattcct actgcaatcg gtaacgcgca attatcgtca
    31861 ggtacagcag ggttatgtgc aaaagcagtg cgctgtaaat gcgcgtctag tttcagtccc
    31921 cgaaacagag atagcggtga agagtccatc cccaaacgat acataacctt cttacgataa
    31981 atactgacgg tttttgttcc cagaccaaat tttttcgcca gttcaattgc cggatgtccg
    32041 gaggataata atatcagcag cgcatatttc gcctgcgtga caccgggagg tagattccac
    32101 caggcgtatt gattgatatt aaacaatacc tcttccggcg tctcgccggc attaaaagca
    32161 tacgtagcag ccacggtttt cttttgtggc ctgtggcaga aacgcagcca ggcttccgga
    32221 agacggagct tctctcgctc cgagcggata gcgcaggata gttcgtcttt taaaacataa
    32281 tccataacgc caaaatattg cagcacacag cgatcgatat aatacaagcg atctgccact
    32341 accaaaactt tacggttctg caaccgcgcc tgcaacgcat gaaaaagata aacatgctca
    32401 tgcgggttca aagctaaaat cagcccggcg tccggcatat cggatagaga atgcaaaagt
    32461 gcggttaatg agttacacgt tttaacgcac ttttccggat atttttgctt aaaaatagac
    32521 tgtagggcat aacaattagt ccagttaata ccgtatataa ttacatttct ca
//
LOCUS       DAJVBX010000024        31084 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.024, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000024 DAJVBX010000000
VERSION     DAJVBX010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 31084)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31084)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31084
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.024"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(125..1249)
                     /locus_tag="OPV72_001010"
     CDS             complement(125..1249)
                     /locus_tag="OPV72_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HCR9913377.1"
                     /translation="MPPLFTINACKSAGCRNLGLPDSPDYVWPDYRLGYPALHCRACG
                     SYPPLFNEGEFRRWASAYIAQYAKEHGHFCPDCYQRTWIRYGRNPGGTQRLQCQYCKK
                     VWTPKQHALNVAETPEQICSIPLLVPFQGANAFQQLYFLFSFDAVRGNILHLSSNFTL
                     LSAGKSLHYHWKGIAPPEGEKGDIIHRIAIKERQFLQRSQFDEIQYGPAALKRNAQGT
                     ILRPVITAHGHFRVLKNRFPDVATHIIAHECFLRGAVITAWAERFRQRLSSLWFVEEE
                     INDDDCRAEWQLLGKTWQGWWQNQWQLWGQGHNRKMVCSLTGSHLEQGVAVNLAASRR
                     FVTWLWQQPEFQQSAHCSAKRVTQILYLLTEKYNSQWNHI"
     gene            1385..2941
                     /locus_tag="OPV72_001011"
     CDS             1385..2941
                     /locus_tag="OPV72_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HCR9913378.1"
                     /translation="MKVKLLAAGILFTLPFWACAKDVTIIYTNDLHAHVEPYKVPWIA
                     DGKRDIGGWANITTLVKQEKAKNKATWFFDAGDYFTGPYISSLTKGKAIIDILNTMQY
                     DAATIGNHEFDHGWDNTLLQLSRAKFPIVQGNIFYEDSSKSFWDKPYTIVEKDGVKIG
                     VIGLHGVFAFNDTVSAATRVGIEARDEIKWLQRYIDELKGKVDLTVALIHEGTPARQS
                     SMGNTDVRRALDKDIQTASQVKGLDILITGHAHVGTPEPIKVGNTLILSTDSGGIDVG
                     KLVLDYQEKPHQFTVKNFELKTIFADEWKPDPQTKQVIDGWNKKLDKVVQQTVAQSPV
                     ELTRAYGESSSLGNLAADALLFTAGKDTQLALTNSGGIRNEIPAGAVTMGAVISTFPF
                     PNELVTMDLTGKQLRSLMEHGAGLSNGVLQVSKGLEMKYDSSKPIGQRVTVLTLNGKP
                     IDDAAVYHIATNSFLADGGDGFAAFTEGQARNTSGGYYVSNAIVDYFKAGNTITDEQL
                     KGMRVADVKK"
     gene            3206..4444
                     /locus_tag="OPV72_001012"
     CDS             3206..4444
                     /locus_tag="OPV72_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014341216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HCR9913379.1"
                     /translation="MINNDPLFDLLNKEQQRQQHSLELIASENFASPAVLAAQGSVLT
                     NKYAEGYYQHRYYGGCKFIDEVEMLAITRAQQLFGARYVNVQPHSGSQANQAVYLALL
                     KPGDKILGMSLQCGGHLTHGSPVNQSGKWFNAFHYGVDAHSGLIDMDEVETIAKRERP
                     RLIIAGGSAYPRHYDFARFRRIADAVGAMLLVDMAHFAGLVAGGCFPSPLAYADVITA
                     TTHKTLRGPRGGMILTNDARLAKKIDSAIFPGLQGGPLMHVIAAKAVALGEALQPEFK
                     RYAGQVIENAQAMCQQLAQRGLTLLTGGTDCHLGIIDLRPQGLTGAQVEYFLELAGIT
                     VNKNTLLGDPQPPSITSGIRIGSAACATRGMKADDFTLIADWISEIIFAIKTPNIADI
                     CADIRQKVTKLTTNYPLPYQ"
     gene            4441..5547
                     /locus_tag="OPV72_001013"
     CDS             4441..5547
                     /locus_tag="OPV72_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase 3"
                     /protein_id="HCR9913380.1"
                     /translation="MMKLAEIQAACGVLCVDLAAVVDNYQTLARHVAPAQCGAVLKAN
                     GYGLGAEAIAPALYAANCRIFFVAQLSEGVALRNILSADAMVVLLNGVMPQAMPFCCA
                     QQITPLLNSVDQVMTWLALQEARSQRRPVLIQLDSGMSRLGVTPEQLARLAAIFRQRG
                     WAAPDYIISHLANADRPDHALNVYQHTLLQQAKKAFPTSRYSLANSCGMFLHPAWRED
                     LCRPGVALFGVAQPWFSTPLKPAFTLTLTILRVQDVPVGTPIGYGSTVTTTRPLRIAT
                     VSAGYADGIPRNLRPPAGVCWRGVRLPVLGRVCMDSFMVDASAIMPTSGDVVEFIGVS
                     QTLEEVAAACDTIPYEIMARLGARFRRIMQPAEA"
     gene            complement(5492..6973)
                     /locus_tag="OPV72_001014"
     CDS             complement(5492..6973)
                     /locus_tag="OPV72_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HCR9913381.1"
                     /translation="MNTANFESIHIMIDAQAWRNLPLHLRLYHAFRQLVISGALADGA
                     KLPSARALAQRLHLSRDTVENAYSQLQRDGFMTRRQGAGSFASRQGVPHIQGQHSLPP
                     SPRQTPTLSARWQTIADRAVSFDARRVQTFTLGLAETRNFPQTIWQNFARQIQRERAH
                     TLMLHGDPQGEQELRQQIAHYLNFERGAKVDAQQIVIVSGARQAFWLCGQLLAEAGQS
                     VVMENPGYPGARQAFSAAQLNLLPIEVDGDGIRVDKLPPAPLVYVTPSHQFPSGHLLS
                     LARRHALIDWAQAHNAWIIEDDYDSEFHYNGAPVACMQGLDREQRTLYVGTFSKTLYP
                     GLRIGYLVVPASLAAHFAAARNLLDGATPALTQLTLARFIASGHFAAHIRTMRSMYAV
                     RQACLAQAINQHLSDWVTPVVTPGGLQMPCWLHEGIDEQQTLNAARRAGLNIAGMRQF
                     WLTHPAPTGWLLGFAAFTPYEIENGVKLLRAALCAENVRQAGP"
     gene            7252..8142
                     /gene="metF"
                     /locus_tag="OPV72_001015"
     CDS             7252..8142
                     /gene="metF"
                     /locus_tag="OPV72_001015"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="HCR9913382.1"
                     /translation="MSFFHANQREALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNS
                     IDRLSSLKPKFVSVTYGANSGERDRTHSVIKGIKERTGLEAAPHLTCIDATRDELRTI
                     ARDYWNNGIRHIVALRGDLPPGSGKPEMYAADLVGLLKEVADFDISVAAYPEVHPEAK
                     SAQADLLNLKRKVDAGANRAITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFK
                     QAKKFADMTNVRIPSWMSLMFEGLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYT
                     LNRAEMSYAICHTLGVRPGL"
     gene            8307..10487
                     /gene="katG"
                     /locus_tag="OPV72_001016"
     CDS             8307..10487
                     /gene="katG"
                     /locus_tag="OPV72_001016"
                     /EC_number="1.11.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catalase/peroxidase HPI"
                     /protein_id="HCR9913383.1"
                     /translation="MSTTDDTHNTLSTGKCPFHQGGHDRSAGAGTASRDWWPNQLRVD
                     LLNQHSNRSNPLGEDFDYRKEFSKLDYSALKGDLKALLTDSQPWWPADWGSYVGLFIR
                     MAWHGAGTYRSIDGRGGAGRGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGQKISWA
                     DLFILAGNVALENSGFRTFGFGAGREDVWEPDLDVNWGDEKAWLTHRHPEALAKAPLG
                     ATEMGLIYVNPEGPDHSGEPLSAAAAIRATFGNMGMNDEETVALIAGGHTLGKTHGAA
                     AASHVGADPEAAPIEAQGLGWASSYGSGVGADAITSGLEVVWTQTPTQWSNYFFENLF
                     KYEWVQTRSPAGAIQFEAVDAPDIIPDPFDPSKKRKPTMLVTDLTLRFDPEFEKISRR
                     FLNDPQAFNEAFARAWFKLTHRDMGPKARYIGPEVPKEDLIWQDPLPQPLYQPTQEDI
                     INLKAAIAASGLSISEMVSVAWASASTFRGGDKRGGANGARLALAPQRDWEVNAVAAR
                     VLPVLEALQKTTNKASLADIIVLAGVVGIEQAAAAAGVSISVPFAPGRVDARQDQTDI
                     EMFSLLEPIADGFRNYRARLDVSTTESLLIDKAQQLTLTAPEMTVLVGGMRVLGTNFD
                     GSQNGVFTDRPGVLSTDFFANLLDMRYEWKPTDDANELFEGRDRLTGEVKYTATRADL
                     VFGSNSVLRALAEVYACSDAHEKFVKDFVAAWVKVMNLDRFDLL"
     gene            complement(10594..11697)
                     /locus_tag="OPV72_001017"
     CDS             complement(10594..11697)
                     /locus_tag="OPV72_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HCR9913384.1"
                     /translation="MDRIIQSPGKYIQGANVIARLGDYLKPMANNWLVVGDKFVLGFA
                     EETLRKSLTDAGLSVEIAPFGGECSQNEIDRLRAVAEKSQCGAVLGIGGGKTLDTAKA
                     LAHFMNVPVAIAPTIASTDAPCSALSVIYTDAGEFDRYLLLPHNPNMVIVDTQIVAGA
                     PARLLAAGIGDALATWFEARACSRSGATTMAGGKCTQAALALAELCYNTLIEEGEKAM
                     LAAEQHVVTPALERVIEANTYLSGVGFESGGLAAAHAIHNGLTAIPDAHHYYHGEKVA
                     FGTLTQLVLENASVEEIETVAALCHSVGLPITLAQLDIKQDIPAKMRIVAEASCAEGE
                     TIHNMPGGATPDEVYAALLVADQYGQRFLQEWE"
     gene            complement(11709..12371)
                     /gene="fsa"
                     /locus_tag="OPV72_001018"
     CDS             complement(11709..12371)
                     /gene="fsa"
                     /locus_tag="OPV72_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HCR9913385.1"
                     /translation="MELYLDTANVAEVERLARIFPIAGVTTNPSIVAASKESIWDVLP
                     RLQNAIGEEGTLFAQTMSRDAKGMVEEAKRLNNAIPGIVVKIPVTAEGLAAIKLLKKE
                     GIVTLGTAVYSASQGLLAALAGAKYVAPYVNRVDAQGGDGIRMVLELQTLLEHHAPDS
                     MVLAASFKTPRQALDCLLAGCQAITLPLDVAQQMLNTPAVESAIEKFEQDWKNAFGNL
                     NL"
     gene            complement(12626..13462)
                     /locus_tag="OPV72_001019"
     CDS             complement(12626..13462)
                     /locus_tag="OPV72_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCR9913386.1"
                     /translation="MYHDVSHLLSRLINGPLPLRQIYFASASGPAPELAYQVDFPRLE
                     IVLEGELTDMSITAPLIPCDVLYVPAGGWNIPQWQTPVTTLSILFGKQQLGFSVVYWD
                     GQQHQNLTKQHVARRGPRIGSFLLQTLNEMQMQPQEQQTARLIVASLLSHCRDLLGSQ
                     IQTASRSRALFEAIREYIDERYAAPLTRESVAQAFYISPNYLSHLFQKTGAIGFNEYL
                     NHTRLEHAKTLLKGYDLKVKEVAHRCGFVDSNYFCRLFRKNTERSPSEYRRQYHSQLT
                     EK"
     gene            complement(13623..15356)
                     /locus_tag="OPV72_001020"
     CDS             complement(13623..15356)
                     /locus_tag="OPV72_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase CptA"
                     /protein_id="HCR9913387.1"
                     /translation="MQSTLLQTKPAFSWKALGWALLYFWFFSTLLQAIIYLTGYSGTN
                     GLRDSLLYSSLWLIPVFLFPGRIRVIAAVIGVVLWAASLAALSYYVIYGQEFSQSVLF
                     VMFETNANEASEYLSQYFSLKIVLVALAYTVAAILLWTRLRPVYIPSPWRYLVSFALL
                     YGLILHPIAMNTFIKHKSMEKTLDSLASRMEPAAPWQFITGYYQYRLQLASLNKLLNE
                     NDALPPLANFQDHSGDAPRTLVLVIGESTQRGRMSLYGYPRETTPELDALHKTDPGLT
                     VFNNVVTSRPYTIEILQQALTFADEKNPDWYLTKPSLMNMMKQAGYKTFWITNQQTMT
                     ARNTMLTVFSKQTDKQFYMNQQRTQSAREYDSNVLAPFKAVLADPAPKKFIIVHLLGT
                     HIKYKFRYPENQGKFDGKTDHVPPGLSSDELESYNDYDNANLYNDYVVASLIKDYKAT
                     DPNGFLLYFSDHGEEVYDTPPHKTQGRNEDSPTRHMYTVPFLLWTSEKWQAAHPRDFS
                     QDVDRKYSSSELIHTWSDLAGLTYDGYDPTRSITNPQFKETTRWIGNPYKKNALIDYD
                     TLPYGDQVGNQ"
     gene            complement(15558..18209)
                     /gene="ppc"
                     /locus_tag="OPV72_001021"
     CDS             complement(15558..18209)
                     /gene="ppc"
                     /locus_tag="OPV72_001021"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004203687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HCR9913388.1"
                     /translation="MNEQYSALRSNVSMLGKVLGETIKDALGEHILDRVETIRKLSKS
                     SRAGNEANRQELLTTLQNLSNDELLPVARAFSQFLNLANTAEQYHSISPKGEAASNPE
                     VIAHTLRKLKNQPDLNDATIKKAVESLSLELVLTAHPTEITRRTLIHKMGEINNCLKQ
                     LDNTDIADYERHQVMRRLRQLIAQSWHTDEIRKQRPSPVDEAKWGFAVVENSLWQGVP
                     NYLRELNEQLEENLGYKLPVDFVPVRFTSWMGGDRDGNPNVTAEITRHVLLLSRWKAT
                     DLFLKDIHVLVSELSMVDATPELLALVGEEGASEPYRYLMKKLRARLMATQSWLEARL
                     KGEKLPKPAGLLTQNEQLWEPLYACYQSLQACGMGIIANGELLDTLRRVKCFGVPLVR
                     IDIRQESTRHTEALGEITRYLGIGDYESWSEADKQAFLIRELNSKRPLLPRNWEPSND
                     TREVLETCKVIAEAPKGSIAAYVISMAKTPSDVLAVHLLLKEAGIGFAMPVAPLFETL
                     DDLNNADDVMTQLLNIDWYRGLIQGKQMVMIGYSDSAKDAGVMAASWAQYQAQDALIK
                     TCEKAGIELTLFHGRGGSIGRGGAPAHAALLSQPPGSLKGGLRVTEQGEMIRFKYGLP
                     EVTVSSLSLYTSAILEANLLPPPEPKDSWRHIMDELSVISCETYRGYVRENKDFVPYF
                     RSATPEQELGKLPLGSRPAKRRPTGGVESLRAIPWIFAWTQNRLMLPAWLGAGTALQK
                     VVEDGKQSELEAMCRDWPFFSTRLGMLEMVFSKADLWLADYYDQRLVAKTLWPLGKEL
                     RDLLEEDIKVVLAIANDSHLMADLPWIAESIQLRNVYTDPLNVLQAELLYRSRLTEEQ
                     GKSPDPRVEQALMVTIAGVAAGMRNTG"
     gene            complement(18578..19729)
                     /gene="argE"
                     /locus_tag="OPV72_001022"
     CDS             complement(18578..19729)
                     /gene="argE"
                     /locus_tag="OPV72_001022"
                     /EC_number="3.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylornithine deacetylase"
                     /protein_id="HCR9913389.1"
                     /translation="MKNVLPPFIEIYRALIATPSISATEESLDQSNASLITLLAGWFS
                     DLGFNVEVQPVPGTRNKFNMLASTGHGAGGLLLTGHTDTVPFDDGRWTRDPFTLTEHD
                     NKLYGLGTADMKGFFAFILDALRDVDVTKLKKPLYILATADEETSMAGARYFSETTAL
                     RPDCAIIGEPTSLQPIRAHKGHISNVVRVLGQSGHSSDPARGVNAIELMHDAIGHIMQ
                     LRDSLKARYHYEAFTVPYPTLNLGHIHGGDASNRICACCELHMDIRPLPGMTLNDLNG
                     LLNDALAPVSERWPGRLTVAELHPPIPGYECPPDHQLVEVVEKLLGTKTDVVNYCTEA
                     PFMQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELITQVVHHFCWH"
     gene            19818..20822
                     /gene="argC"
                     /locus_tag="OPV72_001023"
     CDS             19818..20822
                     /gene="argC"
                     /locus_tag="OPV72_001023"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HCR9913390.1"
                     /translation="MLNTLIVGASGYAGAELVSYVNRHPHMTITALTVSAQSNDAGKL
                     ISDLHPQLKGIVDLPLQPMSDVRDFSADVDVVFLATAHEVSHDLAPQFLQAGCVVFDL
                     SGAFRVNDRAFYEKYYGFTHQYPELLEQAVYGLAEWNADKLNTANLIAVPGCYPTAAQ
                     LSLKPLIDGGLLDLTQWPVINATSGVSGAGRKAAISNSFCEVSLQPYGVFTHRHQPEI
                     AAHLGAEVIFTPHLGNFPRGILETITCRLKAGVTHAQVADVLQKAYGDKPLVRLYDKG
                     VPALKNVVGLPFCDIGFAVQGEHLIVVATEDNLLKGAAAQAVQCANIRFGFAETQSLI
                     "
     gene            20830..21606
                     /gene="argB"
                     /locus_tag="OPV72_001024"
     CDS             20830..21606
                     /gene="argB"
                     /locus_tag="OPV72_001024"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463002.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HCR9913391.1"
                     /translation="MMNPLIIKLGGVLLDSEEALERLFTALVNYRESHQRPLVIVHGG
                     GCVVDELMKGLNLPVKKKDGLRVTPADQIGIITGALAGTANKTLLAWAKKHHIASVGL
                     FLGDGDSVNVTQLDEALGHVGLAQPGSPKLINMLLENGFLPVVSSIGVTDDGQLMNVN
                     ADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTASKAEQLIDQGIITDGMIVKV
                     NAALDAARALGRPVDIASWRHAEQLPALFNGTPIGTRILA"
     gene            21724..23100
                     /gene="argH"
                     /locus_tag="OPV72_001025"
     CDS             21724..23100
                     /gene="argH"
                     /locus_tag="OPV72_001025"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HCR9913392.1"
                     /translation="MALWGGRFTQAADQRFKQFNDSLRFDYRLAEQDIVGSVAWSKAL
                     VTVGVLTADEQRQLEEALNVLLEEVRANPQQILQSDAEDIHSWVEGKLIDKVGQLGKK
                     LHTGRSRNDQVATDLKLWCKETVMELLTANRQLQSALVETAQANQDAVMPGYTHLQRA
                     QPVTFAHWCLAYVEMLARDESRLQDTLKRLDVSPLGCGALAGTAYEIDREQLAGWLGF
                     TSATRNSLDSVSDRDHVLELLSDAAIGMVHLSRFAEDLIFFNSGEAGFVELSDRVTSG
                     SSLMPQKKNPDALELIRGKCGRVQGALTGMMMTLKGLPLAYNKDMQEDKEGLFDALDI
                     WLDCLHMAALVLDGIQVKRPRCQDAAQQGYANATELADYLVAKGVPFREAHHIVGEAV
                     VEAIRQGKPLEALPLADLQKFSRVIGDDVYPILSLQSCLDKRAAKGGVSPQQVAQAID
                     DAKVRLAL"
     gene            23384..24301
                     /gene="oxyR"
                     /locus_tag="OPV72_001026"
     CDS             23384..24301
                     /gene="oxyR"
                     /locus_tag="OPV72_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016831323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator OxyR"
                     /protein_id="HCR9913393.1"
                     /translation="MNIRDLEYLVALAEHRHFRRAADSCHVSQPTLSGQIRKLEDELG
                     VMLLERTSRKVLFTQAGLLLVDQARTVLREVKVLKEMASQQGETMSGPLHIGLIPTIG
                     PYLLPLIIPMLHQTFPKLEMYLHEAQTHQLLAQLDSGKLDCAILALVKESEAFIEVPL
                     FDEPMMLAIYEDHPWANRDRVPMSDLAGEKLLMLEDGHCLRDQAMGFCFEAGADEDTH
                     FRATSLETLRNMVAAGSGITLLPALAVPQERKRDGVVYLPCIKPEPRRTVGLVYRPGS
                     PLRSRYEQLAEAIRGAMDGHFDKALKQAV"
     gene            complement(24284..25684)
                     /gene="sthA"
                     /locus_tag="OPV72_001027"
     CDS             complement(24284..25684)
                     /gene="sthA"
                     /locus_tag="OPV72_001027"
                     /EC_number="1.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Si-specific NAD(P)(+) transhydrogenase"
                     /protein_id="HCR9913394.1"
                     /translation="MPHSWDYDAVVIGSGPGGEGAAMGLVKQGARVAVIERYHNVGGG
                     CTHWGTIPSKALRHAVSRIIEFNQNPLYSDHSRLLRSSFADILNHADNVINQQTRMRQ
                     GFYERNHCEILQGNAHFIDEHTLALECHDGTVETLTAEKFVIACGSRPYHPNDVDFSH
                     PRIYDSDSILSLHHEPRHVIIYGAGVIGCEYASIFRGMDVKVDLINTRDRLLAFLDQE
                     MSDSLSYHFWNSGVVIRHNEEYEKIEGCDDGVIMHLKSGKKLKADCLLYANGRTGNTD
                     SLALENIGLETDSRGQLKVNSMYQTALPHVYAVGDVIGYPSLASAAYDQGRIAAQALV
                     KGEATAHLIEDIPTGIYTIPEISSVGKTEQQLTAMKVPYEVGRAQFKHLARAQIVGMN
                     VGTLKILFHRETKEILGIHCFGERAAEIIHIGQAIMEQKGGGNTIEYFVNTTFNYPTM
                     AEAYRVAALNGLNRLF"
     gene            25883..26518
                     /gene="fabR"
                     /locus_tag="OPV72_001028"
     CDS             25883..26518
                     /gene="fabR"
                     /locus_tag="OPV72_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463006.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional repressor FabR"
                     /protein_id="HCR9913395.1"
                     /translation="MMGVRAQQKEKTRRSLVEAAFSQLSAERSFASLSLREVAREAGI
                     APTSFYRHFRDVDELGLTMVDESGLMLRQLMRQARQRIAKGGSVIRTSVSTFMEFIGN
                     NPNAFRLLLRERSGTSAAFRAAVAREIQHFIAELADYLELENHMPRAFTEAQAEAMVT
                     IVFSAGAEALDIGAEQRRQLEERLVLQLRMIAKGAYYWYRREQEKIAHHSE"
     gene            26534..26893
                     /locus_tag="OPV72_001029"
     CDS             26534..26893
                     /locus_tag="OPV72_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YijD family membrane protein"
                     /protein_id="HCR9913396.1"
                     /translation="MKQSGQDKGTLLLALIAGLSINGTFAALFSAIVPFSVFPVISLV
                     LTVYCLHQRYQNRTMPVGLPGLAAACFILGVLLYSTVVRAEYPDIGSNFFPAVLSVIL
                     VFWIGFKLRNRKQDTAE"
     gene            complement(26940..28040)
                     /gene="trmA"
                     /locus_tag="OPV72_001030"
     CDS             complement(26940..28040)
                     /gene="trmA"
                     /locus_tag="OPV72_001030"
                     /EC_number="2.1.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (uridine(54)-C5)-methyltransferase TrmA"
                     /protein_id="HCR9913397.1"
                     /translation="MTPEHLPTEQYEAQLAEKVARLQSMMAPFSGLVPEVFRSPVSHY
                     RMRAEFRLWHDGDNLYHIMFDQQTKSRIRVDTFPAASQLINTLMKAMIAGVRDNHALR
                     HKLFQIDYLTTLSNQAVVSLLYHKKLDEEWREAATALRDALRAQGLNVHLIGRATKTK
                     IELDQDYIDERLPVAGKEIIYRQVENSFTQPNAAMNIQMLEWALEVTKDSKGDLLELY
                     CGNGNFSLALARNFNRVLATEIAKPSVAAAQYNIAANHIDNVQIIRMAAEEFTQAMNG
                     VREFNRLQGIDLKRYQCETIFVDPPRSGLDSETEKMVQAYPRILYISCNPETLCKNLE
                     TLSQTHTVSRLALFDQFPYTHHMECGVLLTAR"
     regulatory      28155..28348
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            28414..30258
                     /gene="btuB"
                     /locus_tag="OPV72_001031"
     CDS             28414..30258
                     /gene="btuB"
                     /locus_tag="OPV72_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent vitamin B12 receptor BtuB"
                     /protein_id="HCR9913398.1"
                     /translation="MIKKATLLTAFSVTAFSAWAQDTSPDTLVVTANRFQQPRSAVLA
                     PVTIVTRQDIERWQSTSVNDVLRRLPGVDIAQSGGTGQNSSIFIRGTNSSHVLVLIDG
                     VRLNLAGVSGSADLSQFPVSLVQRIEYIRGPRSAIYGSDAIGGVVNIITTRDNPGTEL
                     TAGWGSNSYQNYDLSTQQQLGENTRATLIGDYEYTKGFDVVAKGGTGMQAQPDRDGFL
                     SKTLYGALEHTFSDRWSGFVRGYGYDNRTDYDAYYSPGSPLIDTRKLYSQSWDAGLRF
                     NGERIQSQLVSSYSHSKDYNYDPHYGRYDTSATLDEMKQYNVQWTNSVVVGHGNVGAG
                     VDWQKQTTTPGTGYVPEGYDQRNTGVYLTGLQQLGDFTLEAAARSDDNSQFGRHGTWQ
                     TSAGWEFIEGYRFIASYGTSYKAPNLGQLYGYYGNPNLNPEKSKQWEGAFEGLTAGVS
                     WRISGYRNDINDMIDYDDHLQKYYNEGKARIKGIEATANFDTGPLTHTVSYDYVDARN
                     AITDTPLPRRSKQMAKYQLDWDVYDFDWGVTYQYLGSRYDSDYSAYPYRTVKMGGVSL
                     WDLTVAYPVTSHLTVRGKIANLFDKDYETVYGYQTAGREYTLSGSYTF"
     gene            30203..31054
                     /gene="murI"
                     /locus_tag="OPV72_001032"
     CDS             30203..31054
                     /gene="murI"
                     /locus_tag="OPV72_001032"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HCR9913399.1"
                     /translation="MATKLQDENTPCLAATPSEPRPTVLVFDSGVGGLSVYDEIRRLL
                     PDLHYIYAFDNVAFPYGEKSETFIVERVVEIVTAVQQRYPLSLAVIACNTASTVSLPA
                     LREKFAFPVVGVVPAIKPAARLTANGVVGLLATRATVKRPYTHELIARFANECQIAML
                     GSAELVELAEAKLHGDSVSLEELRRILRPWLRMPEPPDTVVLGCTHFPLLRDELLQVL
                     PEGTRLVDSGAAIARRTAWLLEHEAPDAKSTDANIAYCMAMTPGAEQLLPVLQRYGFE
                     TLEKLAV"
BASE COUNT         6925 a         8050 c         8808 g         7301 t
ORIGIN      
        1 gggccattta tcaaatagct ctattctttt tcagcgtgta aaagcaggat gtgaggtgat
       61 taaatctata gcgccttctg aatgataatc tgtgattttt tatgcgtggc attacatcat
      121 tgagttaaat gtgattccat tgtgagttat atttttccgt cagcaaatac agaatttgtg
      181 tgacgcgttt ggcggaacag tgggcgcttt gctggaattc aggttgttgc catagccagg
      241 taacaaagcg gcgactggcc gccagattaa cggcgacacc ttgttctaag tgggaaccgg
      301 ttaacgaaca gaccattttg cggttgtgac cttgccccca gagttgccac tgattttgcc
      361 accatccctg ccatgttttg cctaacagtt gccactctgc gcggcaatcg tcatcgttta
      421 tctcttcctc aacgaaccac agcgaggaga gacgctggcg aaaccgctcc gcccatgccg
      481 taatgaccgc gccgcgcaaa aaacactcat gggcaatgat gtgtgtcgcg acatcaggaa
      541 agcggttttt cagcacccga aaatgaccat gcgccgtaat caccgggcga agtattgttc
      601 cttgcgcgtt acgtttaagc gccgccgggc catactgaat ctcatcgaac tggctgcgct
      661 gtaaaaattg ccgttcttta atggcgatac ggtgaataat atcgcccttc tcgccctcgg
      721 gcggcgcaat tcctttccag tggtaatgca aactctttcc ggcagaaagt aacgtgaaat
      781 tgctggaaag gtgaagtata ttgccgcgaa cagcatcaaa actgaataaa aagtacaatt
      841 gttggaaggc attcgctccc tgaaacggta cgagcagcgg aatactgcaa atctgttccg
      901 gcgtttcggc gacattcagc gcgtgctgtt ttggcgtcca gaccttctta cagtactggc
      961 actgaagtcg ctgcgttccg ccgggattac gtccataacg aatccatgtt ctttgatagc
     1021 aatcggggca aaagtgacca tgctctttgg catattgcgc gatgtaagca gacgcccagc
     1081 ggcgaaattc cccctcgttg aagagcggtg gataactgcc gcaggcccga caatgcaatg
     1141 ccggataacc caggcgatag tccggccaca cataatccgg cgagtcaggc agcccaagat
     1201 tgcgacaacc agcgcttttg caggcattaa tggtgaacag aggcggcata cattttacca
     1261 acgattttgg caggtcgttg attctgcctt cataaaacgg tacgcgggtg tgaggactct
     1321 cacataaaaa aacctttcag aacgtaacgt agcgaatctt tatatgactg aaagggactt
     1381 atttatgaaa gtaaaactgc ttgctgccgg tattttgttc acgctgccgt tctgggcctg
     1441 cgccaaagat gtcaccatta tttacaccaa cgatctacac gcccatgtgg agccttataa
     1501 agtaccgtgg attgctgacg gtaaacgcga tattggcggt tgggccaata tcactacgct
     1561 ggtgaagcag gaaaaagcca aaaataaggc gacgtggttt tttgatgccg gagattactt
     1621 taccggaccg tatatcagca gcctgacgaa gggtaaagcg attatcgata ttttgaatac
     1681 catgcagtat gacgctgcca ctatcggtaa tcatgagttc gatcatggct gggacaatac
     1741 attgttgcaa ctgagccggg cgaaattccc tatcgtacag ggcaatattt tttatgagga
     1801 cagcagtaaa tccttctggg ataagccgta caccattgtt gaaaaagatg gcgtcaagat
     1861 tggcgtaatc ggcttacacg gtgtctttgc ttttaatgat acggtttctg ccgcgacgcg
     1921 cgtgggcatt gaggctcgcg atgaaattaa gtggctgcaa cgttacattg atgaacttaa
     1981 aggtaaagtc gatctgaccg tcgcgctgat ccacgaaggc accccggccc gccagtccag
     2041 catggggaat accgatgtgc gacgcgcgct ggataaagat attcagaccg caagtcaggt
     2101 aaaagggctg gatattttga ttaccggcca cgcgcatgtc ggtacgccgg aaccgattaa
     2161 agtcggtaat acgctgatcc tctcaacgga cagcggcggt attgatgtcg gcaaactggt
     2221 gctggactac caggaaaagc cgcatcagtt taccgtgaag aacttcgagc tgaagaccat
     2281 ttttgctgat gagtggaagc ccgatccgca aacgaaacag gtgatcgacg gctggaacaa
     2341 aaagctcgat aaagtcgtgc agcaaacggt ggcgcagtcg ccggttgagc tgacccgcgc
     2401 gtatggcgaa tcgtcgtcgc tggggaatct ggcggcggat gcgctgcttt ttacggcggg
     2461 gaaagacacc cagttagcgc ttactaactc tggcggtatc cgcaacgaaa tcccggctgg
     2521 tgcggtgacg atgggggcgg taatcagtac cttcccgttc cctaatgaac tggtcacgat
     2581 ggatttaacc ggtaaacaat tgcgcagcct gatggagcat ggcgccggat taagcaacgg
     2641 cgtgttgcag gtgtctaaag ggctggagat gaagtatgac agcagcaaac ctatcggcca
     2701 gcgggttacc gtgctgacgc tcaatggcaa gccgattgat gatgcggcgg tttatcacat
     2761 cgctaccaac agcttccttg ccgacggcgg cgatggtttt gcggcgttca cggaaggcca
     2821 ggcacggaac acctccggcg gctactatgt gtcgaatgcg atagttgatt actttaaggc
     2881 gggcaacacc atcacggatg agcagctcaa aggaatgcgt gttgcggatg tgaagaagta
     2941 aggggttact tgcctgtgcg caatggcctt tagcgcattc aggccggacg gcggtatgtc
     3001 tggcctggat cattcgtgga ccgcggatat caaccgtctg gcgtagcttc tgtaattttg
     3061 ccgggttacg cgccgcgttc ccggcatgtt cctgccgaaa tttacccctc tatccggtgg
     3121 tctgcgtcct gcgtaaaaag tggcggggtg cgggggaaac tttccctgcg aaaatcatca
     3181 tatgatgaat tttcggggga accgcatgat aaacaacgat ccgctttttg atttacttaa
     3241 taaagagcaa cagcgccagc agcactcgct ggaactgatt gcctcggaga atttcgccag
     3301 ccctgccgtt cttgcggcac aagggtcggt gttaaccaat aaatacgccg aaggctatta
     3361 ccagcaccgc tactacggcg gctgtaagtt cattgatgag gttgagatgc tggcgataac
     3421 ccgcgcgcag caacttttcg gcgcgcgtta tgttaacgtg cagcctcact ccggcagcca
     3481 ggcgaatcag gcggtatatc tggcgctgct gaaacccggc gacaaaattc tgggcatgag
     3541 cctgcaatgc ggcggccatc tcactcacgg ctcgccggtc aatcaatccg gcaaatggtt
     3601 taacgccttt cactatggcg tcgatgcgca tagcggtctt attgatatgg atgaggttga
     3661 gacgatcgcg aagcgtgagc gcccgcggct gattatcgcc gggggatcgg cctacccacg
     3721 acactatgat tttgcccgct ttcgccgcat tgccgatgcc gtcggcgcga tgctgctggt
     3781 ggatatggcg cattttgccg ggctggtggc gggcggctgt ttcccctcgc cgctggcgta
     3841 tgccgatgtg attaccgcca ccacgcataa aacgttgcgc gggccgcgtg gcggcatgat
     3901 tctgaccaac gacgcccggc tggcgaaaaa aatcgacagc gccatctttc ccggcttgca
     3961 gggcgggccg ttgatgcacg ttatcgcggc taaagcggtg gcgcttggcg aagcgctaca
     4021 gcctgaattt aaacgttacg ccgggcaggt aatcgaaaat gcgcaagcga tgtgccagca
     4081 actggcgcag cgcggcctga cgctgttaac gggcggtacc gactgccatc tgggcattat
     4141 cgacctgcgc ccgcaggggt taaccggcgc tcaggtggaa tactttctcg aactggcggg
     4201 gatcacggtc aataaaaaca cgttgctagg cgatccacag ccgccgtcga ttacctccgg
     4261 gattcgcatt ggcagcgcag cctgcgccac ccgcgggatg aaggccgatg attttacgct
     4321 gatcgcggac tggatcagtg aaattatttt tgccatcaag acgccgaata ttgcagatat
     4381 ttgcgccgat attcggcaaa aagtgactaa attaaccacc aactatccgt tgccttacca
     4441 atgatgaaac ttgctgaaat tcaggcggcg tgcggcgttc tttgtgtaga tctcgccgct
     4501 gtcgttgaca attatcaaac gctggcgcgc catgtcgccc ccgcgcaatg cggcgcagta
     4561 ctgaaagcca atggctatgg cttgggggcg gaggcgattg cgccagccct gtatgcggcc
     4621 aattgccgga tcttttttgt cgcgcaactt tctgaagggg tggcgctacg taacatcctg
     4681 tcggctgacg cgatggtggt gttgcttaat ggcgtcatgc cgcaggcgat gccgttttgt
     4741 tgcgcgcaac agatcacacc attgttgaat tccgttgacc aggtgatgac gtggctggcg
     4801 ttacaggagg ctcggtcgca gcggcgtccg gtcttgatcc agcttgactc tggtatgtcg
     4861 cggctggggg tgacgccgga gcaactggcg cggctggccg cgatttttcg ccagcgtggc
     4921 tgggctgcgc cagactatat catcagccat ctggccaacg ccgacaggcc ggatcatgcg
     4981 ttaaatgtct atcagcatac gctactccag caggcaaaaa aggcattccc aaccagccgt
     5041 tattcgctgg caaattcctg cggtatgttt ctgcatccgg cctggcggga agatctttgc
     5101 cgtccgggcg ttgcgctgtt cggcgtcgcc cagccgtggt tttcaacgcc gttaaaaccg
     5161 gcatttacgc tgacgttgac cattttgcgc gtgcaagacg tgccggttgg gacgccgatt
     5221 ggctacggca gtacggttac taccactcgc ccgctgcgta tcgccacggt atccgccgga
     5281 tacgctgatg ggattccgcg taatttgcgt cctccggcgg gcgtgtgctg gcgcggggtt
     5341 cggttgccgg tgttggggcg ggtctgcatg gacagcttta tggtggacgc cagcgccatc
     5401 atgccaacgt ctggcgatgt tgtggagttt attggcgtga gccagacgct ggaagaggtt
     5461 gctgccgcct gcgataccat cccttatgag attatggccc ggcttggcgc acgttttcgg
     5521 cgcataatgc agcccgcaga agcttgactc cattttcaat ctcgtagggg gtaaacgcgg
     5581 cgaatcccaa cagccagccc gtgggcgcgg ggtgcgtcag ccagaactgg cgcatcccgg
     5641 cgatgtttaa cccggcccgc cgcgcggcgt taagggtctg ttgttcgtca ataccttcat
     5701 gcagccagca gggcatttgt aatcctccgg gcgtcactac cggcgtcacc caatcactaa
     5761 gatgctggtt gatggcctgc gccaggcacg cctgccgcac cgcgtacata ctgcgcatgg
     5821 tgcggatatg ggcggcaaaa tggccggatg cgataaatcg cgccagcgtc aattgggtca
     5881 acgcgggcgt tgcgccatca agcaaattac gcgcagcggc aaagtgcgcg gccagcgacg
     5941 caggcaccac cagataacca atgcgcagac cggggtagag cgttttgctg aaggtgccga
     6001 catacagggt gcgctgctcg cgatctaacc cctgcataca ggcgacgggc gcgccgttgt
     6061 agtgaaattc actgtcgtag tcatcttcga taatccaggc attatgcgcc tgtgcccagt
     6121 caatcagggc atgacgccgc gccagagaga gcaaatgacc ggagggaaac tggtgcgacg
     6181 gcgtaacgta aaccagcggc gcaggcggca gtttatccac ccgaataccg tctccatcga
     6241 cttcaatggg aagaaggttg agctgtgcgg cagagaatgc ctgacgcgcg ccgggatagc
     6301 ctggattttc catcaccacc gactgcccgg cctctgccag cagttgcccg catagccaga
     6361 atgcctgacg cgcgccactg acaatcacaa tctgctgcgc gtcgaccttc gcgccgcgtt
     6421 caaaattgag ataatgggca atttgctggc gcagttcctg ctctccctgc ggatcgccat
     6481 gcagcattag cgtatgcgcc cgctcgcgct ggatctggcg ggcaaaattc tgccaaatgg
     6541 tttgcgggaa gtttcgcgtt tccgcaaggc cgagcgtaaa cgtctgcacc cggcgggcat
     6601 cgaaagatac ggcgcgatcg gcaatcgtct gccagcgggc gctaagcgtg ggcgtctggc
     6661 gaggcgatgg cggcaggctg tgctgcccct gaatatgcgg aaccccctgg cggctggcga
     6721 aactcccggc cccttgcctg cgggtcataa agccgtcgcg ctgaagctgg gaataggcat
     6781 tttcgacggt atccctggaa aggtgcagcc gctgggccag cgcgcgagcg gaaggtagct
     6841 ttgcgccatc agccaacgca ccggaaatta ccaattggcg aaaagcgtgg tacaggcgca
     6901 gatgcagcgg tagattgcgc cacgcttgcg cgtcgatcat gatatgtatc gactcgaaat
     6961 tcgctgtgtt catcttctgg ttcccccgtc cctgcgtcgc caaagtcgtt gaatcatatc
     7021 atttacgcct tattttttat gtgttgaaga acacccggaa ccgtatgaag aaggtattgc
     7081 tcaagatgat ggagaatgaa gttttttcaa ctttgctgaa tattcctcat tctttggcgt
     7141 gatttttcag ttgacgtcct tccgcttttc cgtcattttt acatctggac gtctaaacgg
     7201 atagatgttt acagcacaac aaataataac atgcgattga tgaggtaagg tatgagcttt
     7261 tttcacgcca accagcggga agccctgaat cagagcctgg cggaagtaca gggtcagatt
     7321 aacgtttcgt ttgaattttt cccgccgcgc accagtgaaa tggagcaaac cctgtggaac
     7381 tccatcgatc gcctgagcag cctgaaaccg aagtttgttt cggtaacgta tggcgccaac
     7441 tccggggaac gtgaccgcac tcatagtgtt attaaaggca ttaaagagcg tactgggctt
     7501 gaggccgcgc cgcaccttac ctgtattgac gccacgcgcg atgaactgcg caccatcgcc
     7561 cgcgactact ggaataacgg tatccgccac attgttgctt tgcgcggcga tttgccgccg
     7621 ggcagcggta agccggagat gtacgccgcc gatctggttg gtttgctcaa agaggtggcc
     7681 gatttcgata tttcagtagc ggcctatccg gaggtacatc cggaagcgaa aagcgcgcag
     7741 gccgatctgc ttaatctgaa gcgtaaagtg gatgctggcg ctaaccgcgc gataacccaa
     7801 tttttcttcg atgtggaaag ctatctgcgt tttcgcgacc gctgtgtttc cgccggtatc
     7861 gacgtagaaa ttattcccgg cattttaccg gtgtctaact ttaaacaggc gaaaaaattt
     7921 gccgatatga ccaatgtccg cattccgtcc tggatgtcgc tgatgtttga ggggctggat
     7981 gatgacgcag aaacccgcaa gctggtgggc gctaacattg cgatggacat ggtgaaaatt
     8041 ttaagccgcg aaggagtgaa ggatttccac ttctacacgt tgaatcgtgc ggaaatgagt
     8101 tatgccattt gccacacgct gggcgtaaga ccgggtttat aacctccagc tccctgccgg
     8161 gagctttatt acaactcata ttgatctaca tctctgtaac taaaaatata aaaggtatta
     8221 gctatcgaat ctgtggatta attcaactat atctatttgc tcctggtgta tatcgtaacg
     8281 gtaacacttt aaaagggagc tgagatatga gcacgaccga cgatacccat aacacgttat
     8341 ccactggaaa atgtcctttc catcaggggg ggcatgaccg aagcgcaggc gcagggactg
     8401 ccagccgcga ctggtggccg aaccagcttc gtgtggatct tttgaatcaa cattccaacc
     8461 gttctaaccc gctgggcgaa gactttgact accgcaaaga gtttagcaag ttagactact
     8521 ccgccctgaa aggggatctc aaggcgctgc tgaccgattc acaaccgtgg tggcccgccg
     8581 actggggcag ctatgtcggt ttgtttattc gtatggcctg gcatggcgct ggcacctacc
     8641 gttctattga tggtcgtggc ggcgcgggtc gtggtcaaca gcgttttgcg ccgcttaact
     8701 cctggccgga taacgtcagc ctggataagg cgcgtcgttt gttgtggccg attaagcaga
     8761 aatatggcca gaaaatttcc tgggccgacc tgtttattct ggcgggtaac gtggcgctgg
     8821 aaaactccgg cttccgtacc ttcggtttcg gcgccgggcg tgaagatgtc tgggaaccgg
     8881 atctggatgt gaactggggc gatgaaaaag cctggttgac tcaccgacac cctgaagcgc
     8941 tggcaaaagc gccgctgggc gcgaccgaga tgggccttat ctacgttaac ccggaggggc
     9001 cggatcacag cggcgaacca ctttctgccg ccgccgctat tcgcgctacc tttggcaata
     9061 tggggatgaa cgacgaagag accgtggcgt tgatcgctgg cgggcatacc ctcggtaaaa
     9121 cccacggcgc ggcagcagca tcccatgtag gggccgatcc ggaagccgcg ccgattgaag
     9181 cgcagggctt aggttgggcc agcagctatg gtagcggcgt tggcgcggat gctattacct
     9241 ccgggctgga agtggtctgg acgcagacgc cgacccagtg gagcaactat ttcttcgaga
     9301 acctgttcaa atatgagtgg gtacaaaccc gtagtccggc tggcgctatc cagtttgaag
     9361 cggtagacgc gccggatatc atcccggacc cgttcgatcc gtcgaaaaaa cgtaagccaa
     9421 ccatgctggt caccgacctg acgctgcgtt ttgatccgga gttcgagaag atttcccgtc
     9481 gtttccttaa cgatccacag gcctttaatg aagcctttgc tcgtgcctgg ttcaaactga
     9541 cgcacagaga tatgggacca aaagcgcgtt acatcggacc ggaagtgccg aaagaagatc
     9601 tgatctggca ggacccgttg ccgcaaccgc tctaccagcc aacgcaggaa gacattatca
     9661 acctgaaagc ggcgatcgct gcatccgggc tttctattag cgagatggtt tcggttgcct
     9721 gggcatccgc gtctactttc cgcggcggcg ataagcgtgg cggcgctaac ggcgcgcgtc
     9781 tggcattagc gcctcagcgc gactgggagg tcaacgccgt tgcggctcgc gttctgccgg
     9841 tattagaagc gctccagaaa acgacgaata aagcctcgct ggccgatatt attgtgctgg
     9901 cgggcgtggt cggtatcgag caggcggccg ctgctgcggg tgtcagcatc agcgtacctt
     9961 ttgcgccggg ccgggtggat gcgcgtcagg atcagaccga catcgagatg ttctcgctgc
    10021 ttgaaccgat tgccgatgga ttccgtaact atcgtgcgcg tctggatgtg tcgacgaccg
    10081 aatcgctgtt gattgataaa gcgcagcagt taacgttgac cgcgccggaa atgacggtac
    10141 tggttggcgg gatgcgtgtg ctgggaacca actttgacgg cagccagaac ggtgtcttta
    10201 ccgacagacc gggcgtgctc agcactgact tcttcgctaa tctgctggat atgcgttacg
    10261 agtggaagcc caccgacgac gctaatgagc tgttcgaagg ccgggatcgc ctgactggcg
    10321 aggtaaaata cacggcaacc cgcgccgatc tggtgtttgg ttccaactcc gtactgcgcg
    10381 cgctggcgga agtttacgcg tgtagcgatg cgcacgagaa gtttgtgaag gacttcgtcg
    10441 cggcatgggt gaaagtgatg aacctggacc gtttcgatct gttgtaaatc ttatgccgga
    10501 tgacgctaac gcttatccgg cctaccgtct catatgccca ccgggcaaaa aaatccccgc
    10561 gcaattgcgg ggatttttca ttgcaagccg accttattcc cattcctgca agaagcgttg
    10621 accgtactgg tcggcgacca gcagcgcggc gtacacttca tccggcgttg cgccgccagg
    10681 catgttatga atagtttcac cttctgcgca ggaggcttcc gcgacgatgc gcattttggc
    10741 cgggatatcc tgcttaatat ccagttgcgc cagcgtaatc ggcaggccaa cggaatggca
    10801 cagcgcagca acggtttcga tttcttcgac cgacgcgttt tccagcacca gttgcgtcag
    10861 cgtaccgaaa gcgaccttct ccccgtgata atagtggtgc gcatccggaa tcgccgttaa
    10921 accgttatga atcgcgtgcg ctgcggccag accgccgctt tcaaaaccga ccccgctcag
    10981 gtaggtgttg gcttcgatga cacgttccag cgctggcgtg acgacgtgct gttcggcggc
    11041 caacatggct ttttcgcctt cttcgatcag cgtgttatag catagctccg ccagggccag
    11101 cgcggcctgt gtacacttgc cgcccgccat tgtggtggcg ccgctgcgtg agcaggcgcg
    11161 cgcttcaaac caggtcgcca gcgcatcgcc gataccggct gccagcagac gcgccggcgc
    11221 gcccgccact atctgcgtat cgacaatgac catattcggg ttatgcggca gcagcagata
    11281 acggtcaaac tcaccggcat cggtataaat aaccgagagt gcgctgcacg gtgcgtcggt
    11341 agaggcgatg gtcggcgcga tagcgaccgg gacgttcata aagtgcgcca gcgctttggc
    11401 ggtatccagc gttttaccgc cgccgatacc cagtacggcg ccacactgac ttttttcggc
    11461 gacggcgcgc agcctgtcga tctcattttg cgaacattcg ccgccaaacg gggcgatttc
    11521 tactgacaaa ccggcatccg tcaggctttt gcgcagcgtc tcttcggcaa atcccagcac
    11581 gaatttatcg cccacaacca gccagttgtt cgccattggt tttaaataat cgccaagacg
    11641 cgcgatgacg tttgcaccct gaatatactt acctggtgac tgaataatgc gatccataca
    11701 tttctctcct acaggttcag attaccaaaa gcgtttttcc agtcttgctc aaacttctct
    11761 attgctgact ctaccgcagg cgtattgagc atttgttgcg ctacatctaa aggaagggta
    11821 atcgcctggc aacctgccag taagcaatcc agcgcctgcc gcggcgtttt aaagctggcc
    11881 gccagtacca tgctgtcggg cgcgtgatgt tccagtagcg tttgcagctc cagaaccata
    11941 cgaatgccat cgccgccctg cgcatcaacg cggttgacgt agggagcgac atattttgcg
    12001 cccgccagcg ccgccagcag gccctgcgac gcgctgtaga cggcggtgcc cagcgtcacg
    12061 atgccttctt ttttcagcaa tttaatcgct gcaaggcctt cggcggttac cggaatttta
    12121 accacaatgc cggggatggc gttattcagc cgtttggctt cttccaccat ccctttcgcg
    12181 tcgcggctca tggtctgcgc aaataaagtg ccttcttcgc cgatggcgtt ttgcagcctg
    12241 ggcagcacat cccagataga ttctttgctg gctgccacaa tgcttggatt ggtggtgacg
    12301 ccggcaatcg ggaaaatgcg cgccagacgt tcaacttccg ccacgttagc ggtatccaga
    12361 tagagttcca tagtctttct cttcgtgagt tttcgttatg gacaggataa aggagcgtgc
    12421 cccggatgcg ctatgtgaca aatctgccaa aaactggaca aatgtgatgc tcttggtaaa
    12481 gtgtgattta cttcacaagt tggtgatgat taacgtataa cgtgctgttg tatgccatgt
    12541 gggggagtga ggtttttgca ttgatattac aataatccag taaatgcgcg ttttatctac
    12601 tgtattctct ttattggcgt gtggattatt tctccgttag ctggctgtga tactggcggc
    12661 gatactccga aggcgaacgt tccgtatttt tgcgaaacag gcggcagaaa tagttactgt
    12721 cgacaaagcc gcagcggtgc gccacctctt tcactttcag gtcatagccc ttcagcaacg
    12781 ttttggcgtg ttccagtcgc gtatggttca ggtattcgtt aaagccgatg gctcccgttt
    12841 tctggaacag gtgcgagagg taatttggcg agatataaaa cgcctgtgct accgattcgc
    12901 gcgtcaacgg cgcggcgtag cgttcatcaa tatactcccg aatggcttca aaaagcgcac
    12961 ggctacggga ggcggtctgg atttggctgc cgagcagatc gcggcaatgg cttagtaggc
    13021 tggcgacaat caatctggcc gtttgctgct cttgcggctg catctgcatc tcattaagcg
    13081 tttgtaacag gaacgagccg atacgcgggc cacggcgcgc aacgtgctgt ttcgtgaggt
    13141 tttgatgctg ctgaccgtcc cagtagacca cgctgaaacc taactgctgt ttgccaaaca
    13201 gaatgctcag ggtggtgacg ggcgtttgcc actgcgggat gttccagccg ccagccggaa
    13261 cgtagagaac atcgcaagga atgagcgggg cggtaatgct catgtcagta agctcgccct
    13321 ccagcacaat ctccagccgc ggaaaatcca cctggtacgc cagttccggc gctgggccgc
    13381 tggcgctggc aaaataaatc tggcgcagcg gcagcgggcc gttgatgaga cgggagagaa
    13441 ggtggctgac gtcgtgatac atgataatcc cctgccgatc gcaaacagag gaaacagtaa
    13501 cgtcgaaaac cgatgtcctc aagcaattat tgccggatag cggcgctttg cgccttatcc
    13561 ggactacggg agagaagaac gccaggcccg ataagcgtta gcgttatcgg gcaacataca
    13621 ggctattgat taccgacctg atcgccatac ggcaacgtat cataatcaat cagcgcgttt
    13681 ttcttatacg ggttgccaat ccagcgcgtg gtctctttga actgcgggtt ggtgatggaa
    13741 cgcgtcgggt cgtaaccatc ataggtcagg cccgctaagt ccgaccaggt atggataagc
    13801 tcggaactgc tgtacttacg atcgacatcc tgtgagaagt cgcgcggatg cgccgcctgc
    13861 catttctctg aggtccacag caggaacggc accgtataca tatgacgggt tggcgaatct
    13921 tcgtttcgtc cctgcgtctt atgcggcggc gtgtcataca cttcttcacc gtggtcggag
    13981 aagtagagca ggaaaccgtt cggatcggtc gctttatagt ccttaatcag gctggcgaca
    14041 acatagtcgt tatacaggtt cgcgttgtcg taatcgttat acgattccag ttcgtcgctg
    14101 cttaatcccg gcggaacatg gtcggtttta ccatcaaact tgccctggtt ttctggatag
    14161 cggaacttgt atttaatgtg cgttcccagc agatgcacaa taatgaattt tttcggcgcc
    14221 gggtcggcta acaccgcttt aaacggcgcc agcacgttgc tgtcatattc gcgcgcgctt
    14281 tgagtgcgct gctggttcat atagaactgc ttatcagtct gcttagagaa cacggtcagc
    14341 atggtattac gcgccgtcat cgtctgctgg ttagtgatcc agaaggtttt atacccggcc
    14401 tgtttcatca tattcatcag cgatggcttc gtcagatacc agtccgggtt cttttcgtcc
    14461 gcgaacgtta gcgcctgttg caggatctca atggtgtacg gtcgcgaagt taccacatta
    14521 ttaaacacgg tcagcccggg gtcggtttta tgcagcgcgt ccagttccgg cgtggtttcg
    14581 cgcggataac cgtacagact catacggcca cgctgggtcg attcgccaat caccagtacc
    14641 agtgtgcgcg gcgcatcgcc ggagtggtcc tggaagttag ccagcggcgg cagggcatcg
    14701 ttttcattca gcagtttatt cagcgaggcg agctgtaaac ggtactgata gtagccagta
    14761 ataaattgcc acggagcggc gggttccatt cgtgacgcca ggctatccag cgttttctcc
    14821 atcgacttat gcttgataaa ggtattcatc gcgatgggat ggaggatcag cccgtacagc
    14881 agggcaaacg acaccagata acgccagggg gatggaatat aaaccgggcg cagacgtgtc
    14941 cacagcaaaa tcgccgccac cgtataagcc agcgcgacaa gaacaatttt cagactgaaa
    15001 tattggctta aatattcgct ggcttcattg gcgttggttt caaacatcac aaacagcacg
    15061 ctttgcgaga actcctgccc gtagattacg taatagctca gcgccgccag cgaggcggcc
    15121 cagagtacga cgccaataac ggcagcaata acccggatgc ggcctggaaa caaaaagacc
    15181 gggatcagcc atagtgagct gtacagtagc gaatcccgca gaccgtttgt cccactgtat
    15241 ccggtgagat aaataatggc ctgcaggagg gtggaaaaga accaaaagta gagcagtgcc
    15301 cagcccaggg ctttccagct aaacgcgggt ttagtctgga gtaatgtgga ttgcataatg
    15361 agagcctgtc tttaatcgta gcgccaaacg taacgcctga accttaaaag aatctgaagc
    15421 aaacctgctt tatgccgcac gttttgctaa gaaagattta taaatgcaga caggaatata
    15481 ttgaaaaaat gacgaggatg acagcagtat ttcatgccgc ccccacataa ctgcgtgagg
    15541 gcggctttct tttggcgtta gccggtgttg cgcataccgg cggcgacgcc cgcaatcgtg
    15601 accatcaacg cctgttcgac gcgaggatcg ggcgatttgc cctgctcttc agtcagacgg
    15661 gaacgataca gcaattcggc ctgcaacacg tttaatggat cggtataaac gtttcttaac
    15721 tgaatggact ccgcaatcca cggtaagtcg gccatcaggt gcgaatcgtt ggcaatcgcc
    15781 agcaccactt taatgtcttc ttccagtagg tctcgtagct ctttgcccag cggccaaagc
    15841 gttttcgcca ccaggcgctg atcgtaatag tcggccagcc acaggtcggc tttcgagaac
    15901 accatttcca gcatcccaag acgcgtggag aagaacggcc agtcgcggca catggcttcc
    15961 agttcgcttt gtttaccgtc ttccaccact ttttgcagcg cagtacccgc gcccagccag
    16021 gctggcagca tcaggcggtt ttgcgtccag gcgaagatcc acggaatcgc gcgcagcgat
    16081 tcgacgccgc cagttggacg acgtttcgcc ggacgtgagc cgagcggcaa tttgcccagc
    16141 tcttgttccg gcgtcgcgga gcggaagtac ggtacaaagt ctttattttc gcgcacgtaa
    16201 ccgcggtagg tttcacagga gatgacggaa agctcatcca taatatgacg ccagctgtct
    16261 ttcggttccg gcggcggcag caggtttgct tccagaattg cgctggtgta gagcgagagg
    16321 ctgctgacgg tgacttccgg caggccgtat ttgaagcgga tcatctcgcc ctgctcggtc
    16381 acgcgcagac cgcctttcag actgcctggc ggttgcgaaa gcagcgccgc gtgggctggc
    16441 gcgccgccac ggccaataga gccgccgcgg ccgtggaaga gagtgagctc gatgccggct
    16501 ttttcacagg ttttgatcag ggcgtcctgc gcctgatact gcgcccatga cgcggccata
    16561 acgccggcgt cttttgccga gtcggagtag ccgatcatga ccatctgctt accctgaatc
    16621 agcccgcgat accagtcgat attcaacaac tgggtcatca cgtcgtcggc attgttcagg
    16681 tcgtcgaggg tttcaaacag cggtgcgacc ggcatggcaa agccgatacc tgcctctttc
    16741 agcagcaaat gcacagccag cacatcagac ggcgttttcg ccatagaaat cacgtaggcg
    16801 gcgatcgacc cttttggcgc ttcggcaata accttgcagg tttcaagcac ttcgcgggta
    16861 tcgttgctcg gctcccagtt acgcggcagc agcggacgtt tggagttcag ctcgcggatc
    16921 aggaaggcct gcttgtcggc ttccgaccag ctttcgtagt cgccaatacc gaggtagcgg
    16981 gtaatttcgc ccagcgcttc ggtatggcgg gtgctctcct gacggatatc aatacgcacc
    17041 agcggtacgc cgaaacactt cacgcggcgg agcgtgtcga gtaactcgcc gttggcgata
    17101 atgcccatgc cacaggcctg taacgactgg tagcaggcgt acagaggttc ccagagctgc
    17161 tcgttttgcg tcagcaggcc agccggtttg ggcagcttct cgcctttcag acgcgcttcc
    17221 agccaggact gggtcgccat cagacgggcg cgcaattttt tcatcaggta gcgatacggc
    17281 tcagacgcgc cttcttcgcc cactaacgcc agcagctccg gcgtggcgtc gaccatcgac
    17341 agttctgata ccaggacatg aatgtctttc aggaacagat cggtggcttt ccagcggctt
    17401 aacaagagta cgtggcgggt gatctccgcc gtcacgttcg ggttgccgtc tcggtcgccg
    17461 cccatccagg aggtaaaacg taccggcaca aaatccaccg gcaatttgta gccgagattt
    17521 tcttccagtt gttcattcag ttcacgcaga tagttaggta cgccctgcca caggctgttc
    17581 tcaaccacgg cgaagcccca tttggcttca tccaccgggc ttgggcgctg cttgcggatc
    17641 tcatccgtat gccaggattg ggcaatcaac tggcgcaggc gacgcatcac ctggtggcgt
    17701 tcgtagtcgg cgatatcggt attatcaagc tgtttcagac agttattgat ttcccccatc
    17761 ttgtgaataa gcgtacggcg ggtaatttct gtcgggtggg cggttagcac caactccaaa
    17821 gacagcgact ctaccgcttt tttgatggtt gcgtcgttga ggtccggttg gtttttcagt
    17881 ttacgcagag tgtgggcaat cacttccggg ttgctggcgg cttcgccttt tggcgaaatg
    17941 ctgtggtatt gctcggcagt attggccagg ttcaggaact gactaaacgc gcgcgcaact
    18001 ggcagcagct cgtcattaga caaattttgt agcgtggtga gcagctcctg gcgattagct
    18061 tcattgccgg cgcgtgaaga tttggatagc ttacggattg tttctacgcg atcaagaatg
    18121 tgctctccca gcgcatcctt gatggtttct cccagcacct tgccgagcat actgacatta
    18181 ctacgcaacg cggaatattg ttcgttcata tgaccccaga caccccatct ttaatgtaat
    18241 tgccctgtct ctttcatgcc acagcggcag tggctgcgct cgcccgtatg ctagttctgc
    18301 ggaatgggct cgtttgccgc cttgctgtga cgtgaaattt ttctgacttt gctttttagc
    18361 cgtcttttat aaagccacgt aaaacccgtg gcgtcaatta ctgcgaaatc ggttcagcaa
    18421 acgaaaaaat ggcggtaatt tattaaagtt aattcgcatc gtgccaaata agaaatgctt
    18481 atgaacatgt ggcgtagaga tgccggatgg cgctgcgctt atgcggccta caagacgggg
    18541 gaggcccggt aaacatcgtg tcaccgggca atatgcatta atgccagcaa aaatggtgta
    18601 ctacctgggt aatcaattcc cgggttggct taataaaacg cgtttcgaga tattcatccg
    18661 gctgatgcgc ctgattaatt gagcccggac caagcaccag cgttgggcat aatgtctgca
    18721 taaacggcgc ttcagtacag tagttcacca cgtcggtttt tgttcccaac agtttttcta
    18781 ctacttcaac cagttggtgg tccggtggac actcgtaacc tggaatcggc ggatgtaatt
    18841 ccgccaccgt caggcggccc ggccagcgtt cgcttaccgg agccagcgcg tcgttaagca
    18901 gtccattaag gtcgtttaac gtcatgcccg gcagtggacg aatatccata tgcaattcgc
    18961 agcaggcgca gatacggttt gaggcatcgc cgccgtggat atggcccaga ttcagcgttg
    19021 gatacggaac ggtaaacgcc tcgtagtgat accgcgcttt cagcgagtca cgcagttgca
    19081 tgatatggcc aatcgcatcg tgcatcagtt caatggcgtt aaccccacgc gccgggtcgc
    19141 tggaatgacc ggactgcccc aggacgcgaa cgacattaga gatatgccct ttgtgcgcgc
    19201 gtatcggttg caacgacgtc ggttcgccaa tgatcgcgca gtccggacgt aatgccgtgg
    19261 tttcggaaaa ataacgcgcc cccgccatgc tggtctcttc atcggcggtc gccagaatgt
    19321 agagcggctt tttcaacttt gtgacgtcaa cgtcacgtag cgcgtccaga ataaaagcga
    19381 agaagccttt catatccgca gtgcccagac catagagctt attgtcgtgc tcggtcagcg
    19441 tgaacgggtc gcgcgtccag cgtccgtcat caaagggaac tgtgtcggta tggccggtca
    19501 gcagcaaacc gcccgcgcca tgtccggtgc tggcgagcat attaaatttg tttcgcgttc
    19561 ctggaaccgg ttgaacctct acgttgaaac caagatcgct gaaccagcct gcaagcaaag
    19621 tgattaaaga cgcattactt tgatccaggg attcttcggt tgcgcttatc gacggtgtgg
    19681 caatcagagc gcggtaaatc tcgataaatg gcggtaaaac gtttttcatt gttgacacac
    19741 ctcaggtcat gatagtatca atattcatgc attaattatg aataaaaata cattaacgtt
    19801 gagcataaag gaacccgatg ttgaatacgc tgattgtagg cgctagcggt tatgcgggcg
    19861 cagagcttgt aagctacgta aatcgccacc cacatatgac cataaccgct ttgaccgtct
    19921 cagcgcaaag caatgatgca ggaaagttaa tttctgattt acatccgcag ttaaaaggga
    19981 ttgttgacct gccattgcaa ccgatgtcgg atgtacgtga ctttagcgca gatgttgatg
    20041 tggtgttcct ggcgacagcg catgaagtga gccacgatct ggcgccgcag tttttacagg
    20101 ccggatgcgt cgtattcgat ctttccggcg cgtttcgggt aaacgatcgc gccttctatg
    20161 aaaagtatta cggatttact catcagtatc ctgagctgct ggagcaggcg gtgtacggtc
    20221 tggcggagtg gaatgccgat aaactgaaca cggcgaatct gattgcggtt cctggttgct
    20281 atccaaccgc agcgcagttg tcgctaaaac cgctgattga cggcgggctt ctcgatctga
    20341 cgcagtggcc ggtaattaat gccaccagcg gggtgagcgg cgcggggcgc aaggcggcaa
    20401 tatcgaacag tttctgtgaa gtgagtttgc aaccgtatgg tgtgtttacg catcgtcatc
    20461 agccggaaat cgctgcccat ctgggcgcgg aggtcatctt caccccgcat ctggggaatt
    20521 tcccgcgcgg gattctggaa accattacct gccgcctgaa agcgggagta acccatgcgc
    20581 aggtcgccga cgtgttgcaa aaagcctatg gcgacaaacc gctggtgcgc ctgtatgaca
    20641 aaggcgttcc ggcgttaaag aacgtcgtcg ggctgccgtt ctgcgatatt ggttttgccg
    20701 tccagggcga acatctgatt gtggtggcaa ccgaagacaa cttgttgaaa ggcgcagcgg
    20761 cgcaggcggt gcagtgcgct aatattcgtt ttggcttcgc tgaaacgcag tctcttattt
    20821 aagggtgaaa tgatgaatcc attaattatc aagctgggtg gcgtattact ggatagcgaa
    20881 gaggctctgg aacgtctttt taccgcgctg gtcaactatc gtgagtccca tcagcgtccg
    20941 ctggtgattg ttcacggcgg cggttgcgtg gtggatgagc tgatgaaagg gcttaatttg
    21001 ccagtgaaaa agaaagacgg cctgcgcgtg acgcctgccg atcagattgg catcattacc
    21061 ggtgcgctgg cgggaaccgc taacaaaact ctgctggctt gggcgaagaa acaccatatc
    21121 gcctctgttg gtctgtttct gggcgatggc gacagcgtaa acgtgaccca actcgatgaa
    21181 gcgttaggcc acgtcgggct ggcgcaaccg gggtcgccga agctgattaa catgttgctg
    21241 gaaaacggct ttctgccggt ggtcagctcc attggcgtaa cagacgacgg ccaactgatg
    21301 aacgtcaacg ccgatcaggc ggcaaccgcg ctggcggcga cgctgggggc cgatctgatc
    21361 ctgctttctg acgtgagcgg tattctggac ggcaaaggcc agcgtatcgc cgaaatgacg
    21421 gcgtccaaag ccgaacagct tatcgaccag ggcattatta ccgacgggat gattgtgaaa
    21481 gtgaatgcgg ctctcgatgc tgcgcgggcg ctgggtcgtc cggtggatat tgcttcctgg
    21541 cgtcatgcgg aacaattgcc ggcgctgttt aacggcacgc cgattggcac gcgtattctg
    21601 gcttaactat ttgttcgccc gatggcggct gcgccttatc gggcctacgt gaacagaaat
    21661 tgtaagccgg ataagcgtag cgctatccgg cagtgaaatt cgaagaattt aaggaagtct
    21721 attatggcac tttggggtgg gcgttttaca caggcggcag accaacggtt taaacaattc
    21781 aatgattcgt tgcgcttcga ttaccgtctg gcggagcagg atattgtcgg ttctgtggcc
    21841 tggtccaaag cattggtcac ggtaggcgta ctgactgccg atgagcaacg acagttggaa
    21901 gaagcgctga acgtgctgct ggaagaggtt cgcgcgaatc cgcagcaaat cctgcaaagc
    21961 gatgcggaag atatccatag ctgggtggaa ggtaagctca tcgacaaagt gggtcagttg
    22021 ggtaaaaagc tgcacaccgg gcgcagccgt aacgatcagg tggcgacgga cctgaaactg
    22081 tggtgcaaag agacggtgat ggaactgctc accgctaacc gccagctaca gagcgcgctg
    22141 gtggaaaccg cgcaggcgaa ccaggacgcg gtaatgccgg gatataccca tctgcaacgc
    22201 gcgcagccag tgactttcgc ccactggtgt ctcgcgtatg tcgaaatgct ggcgcgcgat
    22261 gaaagccgcc tgcaggacac gcttaaacgt ctggacgtga gtccgctagg ctgcggcgcg
    22321 ttggcgggaa cggcctatga aattgaccgt gaacaattgg caggctggct gggcttcacg
    22381 tctgcgaccc gcaacagcct ggacagcgtg tccgatcgtg accacgtact ggaactgctt
    22441 tctgatgcgg ctatcggcat ggtgcatctg tcacgtttcg cggaagatct gattttcttt
    22501 aattctggtg aagcgggctt tgtagagctt tctgaccgcg tgacttccgg ttcatcgtta
    22561 atgccgcaga agaaaaaccc ggacgcgctg gagctgattc gcggtaagtg cggtcgcgta
    22621 caaggggcgc taaccggcat gatgatgact ttaaaaggtc tgccgctggc gtataacaaa
    22681 gatatgcagg aagacaaaga agggctgttc gatgcgctcg atatctggct tgactgcctg
    22741 catatggcgg cgttggtgct ggacggtatt caggtgaaac gcccacgttg tcaggacgcg
    22801 gcgcaacagg ggtatgccaa cgccaccgag ctggcggatt acctggtcgc gaaaggcgtg
    22861 ccgttccgcg aagcgcacca tattgtcggc gaagctgtgg tagaagctat tcgccagggt
    22921 aagccgctgg aagcgttgcc gctggccgat ttacagaaat tcagccgcgt gattggcgac
    22981 gatgtgtatc cgatattgtc tttgcagtcg tgtctggata aacgggcggc aaaaggcggc
    23041 gtttctccgc agcaggtggc gcaggccatc gacgatgcga aggtgcgcct cgcgttgtag
    23101 gccttataag cgtagcgcca tcaggtaata ctgcccggcc gagcatcagc gacgccgggc
    23161 ttttttacgc aaaaaaaagc ggaccagagg tccgcaaaag ttcacgttgg ctttagttat
    23221 ttcgggttcg agagataccc tctgaacggg cggtgtcttc aagggttaaa cgagaaaccg
    23281 ctccgttctg tgatgtatta ttaatcagaa aggttgatag ggataatcgt tcgttgctat
    23341 gctacctatc gccatgaact atcgtggcga cggaggatga ataatgaata ttcgtgatct
    23401 tgaatatctg gtggcgttag ccgaacatcg ccatttccgg cgagcggcgg actcctgtca
    23461 cgtcagccag ccaaccctta gtgggcaaat acgtaagctg gaagatgagc tgggcgttat
    23521 gctgctggag cgtacgagcc gtaaggtgct gtttacccag gcgggcttac tgctggtgga
    23581 tcaggcgcgt accgtactgc gtgaggtcaa ggtgctcaag gagatggcaa gccaacaagg
    23641 cgagacgatg tccggcccgc tgcatattgg tttaatccca acaattggtc cctatttgct
    23701 gccgcttatc attccaatgt tgcaccagac tttcccgaag ctggaaatgt atctgcatga
    23761 ggcgcaaacg caccagctgt tagcgcaact cgatagcggc aagcttgact gcgctattct
    23821 ggcgctggtg aaagagagcg aggcgtttat cgaagtgccg ctgtttgatg agcccatgat
    23881 gctggctatt tatgaagatc atccgtgggc gaatcgcgat cgcgtgccga tgtccgatct
    23941 ggcgggcgag aaattgctga tgctggaaga tggccactgt ctgcgcgatc aggcgatggg
    24001 gttctgtttt gaagcgggag cggatgaaga tacccatttc cgggcgacca gtctggaaac
    24061 gctgcgcaac atggtggcgg cgggcagtgg tattacacta ctccccgcgc tggccgtacc
    24121 gcaggagcgt aagcgcgacg gcgtggttta tctgccatgc attaagccgg agccgcgtcg
    24181 taccgtgggg ctggtttatc gcccgggatc gccgctgcgt agccgttatg agcaactggc
    24241 agaggccatc cgtggcgcaa tggatggaca tttcgacaag gcgttaaaac aggcggttta
    24301 agccgttcaa cgccgcaacc cgataagctt ccgccatggt tgggtagtta aaggtggtgt
    24361 taacgaagta ttcgatggtg ttaccgccac ctttctgctc catgatcgcc tggccgatat
    24421 gaataatttc ggcggcgcgt tcgccaaagc agtgaatccc cagaatttct ttggtttcgc
    24481 ggtgaaagag aatttttagc gtgccgacgt tcatgccgac gatttgcgct cgcgccagat
    24541 gcttaaactg cgcgcggccc acttcgtaag gcactttcat tgccgttaac tgctgctcgg
    24601 ttttgccgac agaactgatt tccggaatgg tataaatccc ggtggggata tcttcgataa
    24661 gatgcgcggt cgcttcgcct ttcaccagcg cctgcgctgc aatacgcccc tgatcgtagg
    24721 cggcggaggc cagactggga tagccaatca cgtcgcccac cgcatagacg tgcggcaggg
    24781 cggtctggta catactgttg actttgagct gtccacggct gtctgtttcc agaccaatat
    24841 tctccagcgc cagcgaatcg gtgttaccgg tacggccatt agcatagagc aggcagtcag
    24901 ccttcagttt tttgccggat ttcaggtgca tgatgacgcc atcatcgcag ccttcgattt
    24961 tctcatactc ttcattgtgg cgaataacca cgccgctatt ccagaaatgg taagagagag
    25021 agtcggacat ctcctgatcg agaaaggcca gcaggcgatc gcgggtgttg atcagatcca
    25081 ctttcacatc cataccgcgg aatatggacg catattcgca gccgataacg cctgcgccgt
    25141 aaataataac gtggcgcggt tcatggtgga gactcaggat tgagtcgctg tcataaatgc
    25201 gcggatgcga gaaatccaca tcattgggat ggtaaggacg cgaaccacag gcaataacaa
    25261 atttttctgc cgtcagggtt tcaaccgtgc cgtcatggca ttccagcgcc agggtatgtt
    25321 cgtcaataaa atgggcgttg ccctgcaaga tttcacagtg gttacgctca taaaacccct
    25381 gacgcatacg cgtttgttga ttaatcacgt tatcggcatg attaaggata tcggcgaaag
    25441 aagaacgaag gagacgggag tggtcgctat agagcgggtt ttgattaaat tcaataatgc
    25501 ggctgacggc gtggcgaagg gctttggatg gaatggtgcc ccagtgggta catccgccgc
    25561 caacgttatg ataacgctca atcaccgcga cgcgtgctcc ttgcttaacc agacccattg
    25621 cagcgccttc accgccgggg cctgacccta tgacgactgc atcataatcc caggaatgtg
    25681 gcatggtatt actcacctgt ttttatacat aaaataaaca cgatgataac atttgcccag
    25741 ctttaaccca attatcgttg tgcttttttg cgaagccgga gcacaaactg tctgtaaaca
    25801 atcattcaca atccagtgtg aacccgttac ttttattctc tggtatagtg ccgaataagg
    25861 catatggaag gattcagaca ttgtgatggg tgttagagcg caacaaaaag aaaaaacccg
    25921 gcgttcgctg gtggaagccg cattcagcca actgagcgct gagcgaagtt tcgccagcct
    25981 gagtttgcgt gaggtggcgc gtgaagcggg cattgcgcca acgtcgtttt accgtcattt
    26041 tcgcgatgtc gatgaactcg gtctaacgat ggtggatgaa agcggtctga tgctgcgtca
    26101 gttgatgcgt caggcgcgac agcgtatcgc gaaaggcggc agcgtcattc gcacgtcggt
    26161 ctctacattt atggagttta tcggcaacaa tcccaacgcc ttccgtctgt tgttgcgcga
    26221 gcgttccggc acttccgcgg cgtttcgtgc cgccgtcgcg cgggagattc agcattttat
    26281 tgcggaactt gccgactatc tggaactcga aaaccatatg ccgcgcgcgt ttactgaagc
    26341 ccaggccgaa gcgatggtga ctattgtctt tagcgcgggc gcagaggcgt tggacatcgg
    26401 cgctgaacag cgtcggcaat tagaagagcg gctggtattg caactgcgca tgattgcgaa
    26461 aggggcgtat tactggtatc gccgtgagca agagaaaata gcacatcatt ccgaataacg
    26521 tgaaggacga gtaatgaaac agtcaggtca agataaaggt acgctgttgc tggcgctcat
    26581 cgctggctta tcgattaacg gcacattcgc ggcgctgttt agcgctattg tgccgttctc
    26641 cgtattcccg gttatctcgc tggtactgac ggtatattgc ctgcatcagc gctaccaaaa
    26701 tcgtactatg ccggtaggtt tgccggggtt ggccgccgct tgtttcattc ttggcgtttt
    26761 actgtatagc actgtcgtgc gtgcagaata tccggatatc ggctctaatt tcttcccggc
    26821 ggtgctgtcg gtgattctgg tattctggat tggctttaag ctgcgtaacc gcaagcagga
    26881 caccgcggag tagtgtgcga atgccggatg gcggtataac cggccatccg acgtacattt
    26941 taccttgcgg tgagtaatac cccgcattcc atatgatgcg tatacgggaa ctgatcgaat
    27001 agcgccaggc gagacaccgt gtgcgtctgg cttaacgttt ccaggttttt gcacaacgtt
    27061 tccggattgc aggaaatgta cagaatacgt ggataagcct gcaccatttt ttctgtttcg
    27121 ctgtccagac cgctgcgcgg cggatcgaca aaaatggttt cgcactgata gcgcttcagg
    27181 tcgatcccct gcaggcggtt aaactcacga acgccgttca tcgcctgggt aaactcttcc
    27241 gccgccatgc gaataatttg cacattatca atatgattag cggcaatatt gtactgtgcg
    27301 gcagcgacgg acggtttggc gatttcggtt gccagcacgc ggttaaaatt gcgcgccagc
    27361 gctaaagaaa aattgccgtt gccgcaatac aactcaagca gatcgccttt tgagtctttc
    27421 gtcacctcca gcgcccactc taacatctga atattcatgg cggcgtttgg ctgcgtaaag
    27481 ctgttttcga cctggcggta gatgatctct ttacctgcca caggcagacg ctcatcaata
    27541 taatcctgat ccaattcgat cttggtttta gtagcccggc caatcaggtg tacgttcaga
    27601 ccttgcgcgc gtaaagcatc gcgtaacgca gtggcggctt cacgccactc ttcgtccagc
    27661 ttcttatggt acagcaacga cactaccgcc tggttgctca aggtcgtgag ataatcgatc
    27721 tggaacagct tatgccgcag tgcatgatta tcgcgcacgc cggcaatcat cgccttcatt
    27781 aaggtattaa tcagttggct ggccgccggg aatgtgtcaa cgcgaatccg gcttttggtc
    27841 tgctgatcaa acataatgtg gtacaggtta tcgccgtcat gccacaggcg aaattccgca
    27901 cgcatacgat agtgactgac cggcgagcga aatacttccg gaaccaggcc agaaaacggc
    27961 gccatcatac tctgcaagcg cgccactttt tcggccagct gcgcctcata ctgttctgtc
    28021 ggaagatgtt cgggggtcat atcgcatcct gaataataaa agtacgcggg gattgtaggg
    28081 attgctcagt ggatgtccag ctattgatga tttctgattt gtgatgcgcg gtctggacag
    28141 ggtgttgtga cagacggtag catccgtggg ccggtcctgt gagttaatag ggaatccagt
    28201 gaaaatctgg agctgacgcg cagcggtaag gaaaggtgag atgagagcgt aagcagacac
    28261 tgcctccggc gggaagtcat catttctgct atccagtcaa cggataaccc tccaagcccg
    28321 aagacctgcc ggctaacgtc gcatctggtt tttcatcatc gcgtactatc gatgaagcct
    28381 gcggcatcct tcttatattg tggatgcttt acaatgatta aaaaagctac gctgctgacg
    28441 gcgttctccg tcacggcctt ttcagcttgg gcgcaggaca ctagcccgga tacactggtt
    28501 gtcaccgcca accgttttca gcagccgcgc agcgcggttc tggcgcccgt taccatcgtg
    28561 acgcgtcagg atattgaacg ctggcaatcg acctccgtaa atgatgttct acgccgtttg
    28621 cctggcgtcg atattgcgca gagcggcggc accggacaaa actcctccat tttcattcgc
    28681 ggcaccaact ccagccatgt actggtattg attgacggcg tgcgtctgaa tttagcaggc
    28741 gtgagcgggt ccgccgatct cagccagttc ccggtgtcgc tggtacagcg cattgaatat
    28801 attcgcggtc cgcgttccgc tatttatggt tccgatgcta tcggcggcgt agtgaatatc
    28861 attacgacgc gcgataaccc aggcacagaa ttaaccgctg gatggggaag caatagctac
    28921 cagaattacg acctctcgac gcaacagcaa cttggcgaaa acacgcgggc gacgttgatc
    28981 ggcgattacg aatacaccaa agggtttgac gtggtagcga aaggcggtac cgggatgcag
    29041 gcgcagcctg accgggacgg ctttttgagt aaaacgcttt atggcgcgtt agagcatacc
    29101 ttttctgatc gctggagcgg attcgtgcgt ggttatggct acgataaccg taccgattac
    29161 gacgcctatt actcgccggg ctcgccgctg attgatacac gcaaacttta tagccaaagc
    29221 tgggacgccg ggctgcgctt taatggcgaa cgtattcagt ctcagctagt ttcaagctat
    29281 agccacagta aagattacaa ctatgatccg cactatggtc ggtatgatac ctccgccacg
    29341 ctggatgaga tgaaacagta caatgttcaa tggaccaaca gtgtggttgt ggggcacggt
    29401 aatgttgggg cgggcgtaga ctggcagaaa cagactacca cgccaggtac cggctatgtg
    29461 cccgagggat atgaccagcg taataccggg gtttacctga caggattaca acagttgggt
    29521 gacttcaccc tggaagcggc ggcgcgcagt gatgacaact cccagtttgg tcgtcacggt
    29581 acatggcaaa ccagcgcggg atgggagttt atagaaggtt atcgctttat tgcctcctac
    29641 ggaacctcct acaaagcgcc taatttgggc cagctgtatg ggtattacgg taatccgaac
    29701 ctgaatcctg aaaagagtaa acagtgggaa ggcgcatttg aagggctcac cgctggcgtc
    29761 agctggcgta tttcaggtta tcgtaacgat attaatgaca tgatcgatta tgacgatcat
    29821 ctgcaaaaat attacaacga aggtaaggcg cgtattaaag gtattgaggc gacggcgaat
    29881 ttcgataccg gaccgttaac gcatacggtc agttatgatt acgttgatgc gcgtaatgcg
    29941 attaccgata cgccattacc ccggcgttcc aaacagatgg caaaatatca acttgactgg
    30001 gacgtttacg attttgactg gggggtgaca tatcaatacc ttggttcccg ctatgattcg
    30061 gattactccg cttacccata ccggacagta aaaatgggcg gcgtcagttt atgggatctt
    30121 acggttgcat atccggtcac ctcacatctg acagttcgtg gtaaaatagc caacctgttc
    30181 gacaaagatt acgagacagt ttatggctac caaactgcag gacgagaata caccttgtct
    30241 ggcagctaca ccttctgaac cacgtcccac cgtgctggta tttgattccg gcgtcggtgg
    30301 attgtcggtc tatgatgaga ttcggcggct cctgccggat ctccactata tatatgcttt
    30361 cgataacgtg gctttcccct acggggaaaa gagcgaaacg tttatcgttg agcgcgttgt
    30421 cgagattgtg actgcggtac agcagcgcta tcccctttca ctggcggtga ttgcctgtaa
    30481 taccgccagt acggtctcac ttcccgcatt acgtgaaaag tttgccttcc cggtggtggg
    30541 cgttgtgcct gcgattaaac cagcggcgcg gcttaccgcc aatggcgtcg tcgggctact
    30601 ggcgacgaga gccacggtca aacgtcctta tactcacgag ctgattgcgc gcttcgccaa
    30661 tgaatgtcag atagcgatgt tggggtcggc agaactggtg gaactggcgg aagctaaatt
    30721 acatggcgat tcggtatcgc tggaagaact gcgccgtata ttacgcccat ggctacgaat
    30781 gccggagccg cctgacacgg tcgttctggg gtgtacgcat ttccctctat tacgggacga
    30841 gcttttgcaa gtcctgcccg aagggacgcg gttagtggat tccggcgcgg cgatagcgcg
    30901 tcgtacagcc tggctgttgg aacatgaagc gccggatgcg aaatcaaccg atgccaatat
    30961 tgcttattgc atggcaatga cgccaggagc tgaacaatta ttacccgttt tacagcgtta
    31021 tggctttgaa acgctcgaaa aactggcggt ttaatggcgt tttgggtaaa taccaggcac
    31081 ttga
//
LOCUS       DAJVBX010000025        29836 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.025, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000025 DAJVBX010000000
VERSION     DAJVBX010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 29836)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29836)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29836
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.025"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            2..562
                     /locus_tag="OPV72_001033"
     CDS             2..562
                     /locus_tag="OPV72_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310599.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebB family permuted papain-like enzyme"
                     /protein_id="HCR9913400.1"
                     /translation="MVFTCIGAALFGQISTASQCWSNHVGIIIGHNGDDYLVAESRVP
                     LSTVTTLSLFIQRSAGQRYAVRRLCGGLTVEQKLAIMEQVPARLNKFYHTGFKYESSR
                     QFCSKFVFDIYKEALCIPVGDIETFEELLHSNPDAKLTFWKFWFLGSIPWDRKTVTPA
                     SLWQHPNLELISACGIENPQREAEGE"
     gene            complement(564..1085)
                     /gene="ruvC"
                     /locus_tag="OPV72_001034"
     CDS             complement(564..1085)
                     /gene="ruvC"
                     /locus_tag="OPV72_001034"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005068993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HCR9913401.1"
                     /translation="MSIILGIDPGSRITGYGVIRQVGRQLTYLGSGCIRTKVDDLPSR
                     LKLIYAGVTEIITQFQPDYFAIEQVFMAKNADSALKLGQARGVAIVAAVNQELPVFEY
                     AARQVKQTVVGIGSAEKSQVQHMVRTLLKLPANPQADAADALAIAITHCHVSQNAMQM
                     SESRLNLARGRLR"
     gene            complement(1122..1862)
                     /locus_tag="OPV72_001035"
     CDS             complement(1122..1862)
                     /locus_tag="OPV72_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCR9913402.1"
                     /translation="MAGHSKWANTRHRKAAQDAKRGKIFTKIIRELVTAAKLGGGDPD
                     ANPRLRAAVDKALANNMTRDTLNRAIARGVGGDEDSNMETIIYEGYGPGGTAIMIECL
                     SDNRNRTVAEVRHAFSKCGGNLGTDGSVAYLFSKKGVISFEKGDEDTIMEAALEAGAE
                     DVVTYDDGAIDVYTAWEEMGKVRDALEAAGLKADSAEVSMIPSTKADMDAETAPKLLR
                     LIDMLEDCDDVQEVYHNGEISDEVAATL"
     gene            complement(1892..2344)
                     /gene="nudB"
                     /locus_tag="OPV72_001036"
     CDS             complement(1892..2344)
                     /gene="nudB"
                     /locus_tag="OPV72_001036"
                     /EC_number="3.6.1.67"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin triphosphate diphosphatase"
                     /protein_id="HCR9913403.1"
                     /translation="MKDKVYKRPVSVLVVIFAQDTKRVLMLQRRDDPDFWQSVTGSIE
                     EGETALQTAVREVKEEVTIDVAAEQLTLVDCQRTVEFEIFSHLRHRYAPGVMHNTEFW
                     FCLALPHERQVIFTEHLTYQWLDAPDAAALTKSWSNRQAIEEFVINVA"
     gene            complement(2447..4219)
                     /gene="aspS"
                     /locus_tag="OPV72_001037"
     CDS             complement(2447..4219)
                     /gene="aspS"
                     /locus_tag="OPV72_001037"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HCR9913404.1"
                     /translation="MRTEYCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGI
                     VQVFFDPDRADALKLASELRNEFCIQVTGTVRARDAKNVNADMATGEIEVLASSLTII
                     NRADSLPLDANHVNTEEARLKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDDHGFLDI
                     ETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRD
                     EDLRADRQPEFTQIDVETSFMTAPQVREVMEALVRHLWLEVKGVDLGDFPVMTFAEAE
                     RRYGSDKPDLRNPMELVDVADLLKSVEFAVFAGPANDPKGRVAALRVPGGAQLSRKQI
                     DDYGNFVKIYGAKGLAYIKVNERAKGLDGINSPVAKFLTADIVEAILERTGAQDGDMI
                     FFGADNKKVVADALGALRLKLGKDLSLTDEDKWAPLWVIDFPMFEDDGEGGLTAMHHP
                     FTAPRDMTASELKTAPEEAVANAYDMVINGYEVGGGSVRIHNGEMQQTVFGILGINEQ
                     EQREKFGFLLDALKYGTPPHVGLAFGLDRLTMLLTGTDNIRDVIAFPKTTAAACLMTE
                     APSFANQAALTELGIQVVKKAENN"
     gene            4544..5110
                     /locus_tag="OPV72_001038"
     CDS             4544..5110
                     /locus_tag="OPV72_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HCR9913405.1"
                     /translation="MLKLNATTTALVVIDLQEGILPFAGGPYTANEVVARAARLAEKC
                     RANGSPVVMVRVGWSDDYAEALKQPVDAATPAHALPENWWTWPTALGKKDSDLEVTKR
                     QWGAFYGTDLELQLRRRGIDTIILCGISTNIGVESTARNAWELGFNLIIAEDACSAAS
                     SEQHQSSMTHIFPRIGRVRSVEDILNAL"
     gene            5107..5925
                     /locus_tag="OPV72_001039"
     CDS             5107..5925
                     /locus_tag="OPV72_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HCR9913406.1"
                     /translation="MIYIGLPQWSHPKWARLGITSLEEYARHFNCVEGNTTLYALPKA
                     EIVDRWYAQTTDDFRFCFKFPATISHQAALRHCDDLVQAFFTRLAPLETRIGQYWLQL
                     PAAFGPRDLPALWQFLDALPATFTYGVEVRHPCFFDKGEDEQRLNRGLHARGVNRVIL
                     DSRPVHAAHPHSEAVRDAQRKKPKVPVHAVVTASHPMVRFIGSDNMAQNREFFAAWLQ
                     KLPQWRQTTTPFLFLHTPDIAQAPELVNTLWHDLRSVLPEIGTAPSIPQQSSLF"
     gene            5978..6373
                     /locus_tag="OPV72_001040"
     CDS             5978..6373
                     /locus_tag="OPV72_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MAPEG family protein"
                     /protein_id="HCR9913407.1"
                     /translation="MVSALYAVLGALLLMKFSFNVVRLRMQYRVAYGDGGFSELQSAI
                     RIHGNAVEYIPVALVLLLFMEMNGAETWMVHICGIILIAGRLMHYYGFHHRLFRWRRA
                     GMSATWCALLLMVLANLWYMPWELVFSLY"
     gene            6414..7157
                     /gene="cmoA"
                     /locus_tag="OPV72_001041"
     CDS             6414..7157
                     /gene="cmoA"
                     /locus_tag="OPV72_001041"
                     /EC_number="2.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxy-S-adenosyl-L-methionine synthase CmoA"
                     /protein_id="HCR9913408.1"
                     /translation="MSHRDTLFSAPIARLGDWTFDERVAEVFPDMIQRSVPGYSNIIS
                     MIGMLAERFVQPNTQVYDLGCSLGAATLSVRRNIRHEHCRIIAVDNSPAMIERCRRHI
                     DAYKAPTPVEVVEGDIRDITIENASMVVLNFTLQFLEPAERQALLDKIYLGLNPGGAL
                     VLSEKFSFEDAKVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVETHKARL
                     RQAGFEHSELWFQCFNFGSLVALKAGVAA"
     gene            7154..8125
                     /gene="cmoB"
                     /locus_tag="OPV72_001042"
     CDS             7154..8125
                     /gene="cmoB"
                     /locus_tag="OPV72_001042"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic
                     acid(34) synthase CmoB"
                     /protein_id="HCR9913409.1"
                     /translation="MIEFGNFYQLIAKNHLSHWLETLPAQIAAWQREQQHGLFKQWSN
                     AVEFLPEITPWRLDLLHSVTAESETPLSEGQLKRIDTLLRNLMPWRKGPFSLYGVDID
                     TEWRSDWKWDRVLPHLSDLTGRTILDVGCGSGYHLWRMIGAGAHLAVGIDPTQLFLCQ
                     FEAVRKLLGNDQRAHLLPLGIEQLPALKAFDTVFSMGVLYHRRSPLEHLWQLKDQLVN
                     EGELVLETLVVDGDENTVLVPGDRYAQMRNVYFIPSAPALKKWLEKCGFVDVRIADVC
                     VTTTEEQRRTEWMVTESLADFLDPNDRSKTVEGYPAPQRAVLIARKP"
     gene            complement(8361..9108)
                     /gene="cutC"
                     /locus_tag="OPV72_001043"
                     /pseudo
     CDS             complement(8361..9108)
                     /gene="cutC"
                     /locus_tag="OPV72_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460864.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
     gene            complement(9128..9697)
                     /locus_tag="OPV72_001044"
     CDS             complement(9128..9697)
                     /locus_tag="OPV72_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCR9913410.1"
                     /translation="MANWQHIDELHDISADLPRFTLAFRELSTRLGLQINALEADHIS
                     LRCHQNTTAERWRRGFEQCGELLSENIINGRPICLFKLHEPVCVEHWRFSVIELPWPG
                     EKRYPHEGWEHIEIVLPGEPETLNARALALLSDEGLSQPGIVVKTSSPQGEHERLPNP
                     TLAVTDGRVTVKFHPWSIEAIVASEQAAH"
     gene            9934..11667
                     /gene="argS"
                     /locus_tag="OPV72_001045"
     CDS             9934..11667
                     /gene="argS"
                     /locus_tag="OPV72_001045"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HCR9913411.1"
                     /translation="MNIQALLSEKVSQAMIAAGAPADCEPQVRQSAKVQFGDYQANGM
                     MAVAKKLGMAPRQLAEQVLTHLDLSGIASKVEIAGPGFINIFLEPAFLAEQVQQALTS
                     DRLGVSQPTRQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHHVIRANHVG
                     DWGTQFGMLIAWLEKQQQENAGDMALADLEGFYRDAKKHYDEDETFAERARNYVVKLQ
                     SGDTYFREMWRKLVDITMTQNQITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKG
                     LAVESEGATVVFLDEFKNKEGDPMGVIIQKKDGGYLYTTTDIACAKYRYETLHADRVL
                     YYIDSRQHQHLMQAWTIVRKAGYVPDSVPLEHHMFGMMLGKDGKPFKTRTGGTVKLAD
                     LLDEALERARRLVAEKNPDMPADELEKLANAVGIGAVKYADLSKNRTTDYIFDWDNML
                     AFEGNTAPYMQYAYTRVLSVFRKADIDEQALASAPVIISEDREAQLAARLLQFEETLT
                     VVAREGTPHVMCAYLYDVAGLFSGFYEHCPILSAENDAVRNSRLKLAQLTAKTLKLGL
                     DTLGIETVERM"
     gene            11856..13025
                     /gene="mrdA"
                     /locus_tag="OPV72_001046"
     CDS             11856..13025
                     /gene="mrdA"
                     /locus_tag="OPV72_001046"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: protein motif:HMM:TIGR03423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HCR9913412.1"
                     /translation="MTFKDFDAEEKLFLRRVIVAFGVVVVCFGILIFNLYNLQIRQHH
                     YYTTRSNENDIKMLPVAPTRGIIYDRNGIPLVRNVTWYDIAVTPYKIADMDALLKQLT
                     PIVDLSPDDIADFRRALKSSSRYRPVVLKNALTDVEIARFAVNQFHFNGVTINSYQDR
                     QYPYGAELAHVLGYVSKINDNDLKALDKKGLAENYAADHNIGKQGIERYYENDLHGKT
                     GYQEVEVDNHGRIVRLLKDVPPIAGKNIHLTLDLHLQEYIESLLAGQRAAVLVEDPHD
                     GSVLAMVSMPSYDPNPFVKGISYQDYGKLLHDKNLPLINRVTQGLYPPASTVKPYMAM
                     SALLCGIITPQTTFFGAPTWTLPGTQRHYRDWKKTGHGMLDVTKAIEESADTFFY"
     gene            13035..13727
                     /locus_tag="OPV72_001047"
     CDS             13035..13727
                     /locus_tag="OPV72_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000971841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HCR9913413.1"
                     /translation="MMGIDRIDTMLSQFGYGKPTGIDLSEEYDGLLPSRAWKQRVHKK
                     AWYQGDTISVGIGQGYWIATPIQMVKAMVALINNSKVIAPHLLLNEESGKTVVPYRPS
                     GTPAQIADPASPYWGLVRQAMYGMANAPNGTGYKFFHTAPYGIAAKSGTSQVFSLKEN
                     QTYNAKMIPIRLRDHVFYTAFAPYKNPKVAIALILENGGSDGVTAAPIMRKILDHLFD
                     PQADTTQSGQAP"
     gene            complement(13781..14920)
                     /locus_tag="OPV72_001048"
     CDS             complement(13781..14920)
                     /locus_tag="OPV72_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 105 protein"
                     /protein_id="HCR9913414.1"
                     /translation="MMVYPVKHSPLLRQPEHFIARDELKALVQKVTHNLVNIKDETGE
                     FLLRLDDGRVIDTKGWAGWEWTHGVGLYGMYHYYQQTGDQTMRKIIDDWFADRFAEGA
                     TTKNVNTMAPFLTLAYRYEETRNPAYLPWLETWAEWAMNEMPRTDYGGMQHITLAEEN
                     HQQMWDDTLMMTVLPLAKIGKLLNRPEYVEEATYQFLLHVQNLMDKETGLWFHGWSYD
                     GHHNFANARWARGNSWLTIVVPDFLELLDLPENNAVRRYLVQVLNAQIAALAKCQDES
                     GLWHTLLDDPHSYLEASATAGFAYGILKAVRKRYVERHYAQVAEKAIRGIVKHISPEG
                     ELLQTSFGTGMGHDLDFYRHIPLTSMPYGQAMAMLCLTEYLRNYF"
     gene            complement(15157..15549)
                     /gene="flhe"
                     /locus_tag="OPV72_001049"
     CDS             complement(15157..15549)
                     /gene="flhe"
                     /locus_tag="OPV72_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlhE"
                     /protein_id="HCR9913415.1"
                     /translation="MRKWLALLLFPLTVQAAGEGAWQDSGMGVTLNYRGVSASSSPLS
                     ARQPVSGVMTLVAWRYELNGPTPAGLRVRLCSQSRCVELDGQSGTTHGFAHVPAVEPL
                     RFVWEVPGGGRLIPALKVRSNQVIVNYR"
     gene            complement(15549..17627)
                     /gene="flhA"
                     /locus_tag="OPV72_001050"
     CDS             complement(15549..17627)
                     /gene="flhA"
                     /locus_tag="OPV72_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
                     /protein_id="HCR9913416.1"
                     /translation="MANLVAMLRLPSNLKSTQWQILAGPILILLILSMMVLPLPAFIL
                     DLLFTFNIALSIMVLLVAMFTQRTLDFAAFPTILLFTTLLRLALNVASTRIILMEGHT
                     GAAAAGKVVEAFGHFLVGGNFAIGIVVFIILVIINFMVITKGAGRIAEVGARFVLDGM
                     PGKQMAIDADLNAGLIGEDEAKKRRSEVTQEADFYGSMDGASKFVRGDAIAGILIMVI
                     NVVGGLLVGVLQHGMSMGSAAESYTLLTIGDGLVAQIPALVISTAAGVIVTRVSTDQD
                     VGEQMVGQLFSNPRVMLLAAAVLGLLGMVPGMPNLVFLLFTAALLGLAWWLRGREEKA
                     PEEPQPVKMPENNSVVEATWNDVQLEDSLGMEVGYRLIPMVDFQQDGELLGRIRSIRK
                     KFAQDMGFLPPVVHIRDNMDLQPARYRILMKGVEIGSGDAYPGRWLAINPGTAAGTLP
                     GEKTVDPAFGLDAIWIESALKEQAQIQGFTVVEASTVVATHLNHLIGQFSAELFGRQE
                     AQQLLDRVSQEMPKLTEDLVPGVVTLTTLHKVLQNLLAEKVPIRDMRTILETLAEHAP
                     LQSDPHELTAVVRVALGRAITQQWFPGNEEVQVIGLDTALERLLLQALQGGGGLEPGL
                     ADRLLAQTQEALSRQEMLGAPPVLLVNHALRPLLSRFLRRSLPQLVVLSNLELSDNRH
                     IRMTATIGGK"
     gene            complement(17620..18771)
                     /gene="flhB"
                     /locus_tag="OPV72_001051"
     CDS             complement(17620..18771)
                     /gene="flhB"
                     /locus_tag="OPV72_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system protein
                     FlhB"
                     /protein_id="HCR9913417.1"
                     /translation="MAEESDDDKTEAPTPHRLEKAREEGQIPRSRELTSLLILLVGVC
                     IIWFGGESLARQLAGMLSAGLHFDHRMVNDPNLILGQIILLIKAAMMALLPLIAGVVL
                     VALISPVMLGGLIFSGKSLQPKFSKLNPLPGIKRMFSAQTGAELLKAVLKSTLVGCVT
                     GFYLWNHWPQMMRLMAESPIVAMGNALDLVGLCALLVVLGVIPMVGFDVFFQIFSHLK
                     KLRMSRQDIRDEFKESEGDPHVKGKIRQMQRAAAQRRMMEDVPKADVIVTNPTHYSVA
                     LQYDENKMSAPKVVAKGAGLIALRIREIGAEHRVPTLEAPPLARALYRHAEIGQQIPG
                     QLYAAVAEVLAWVWQLKRWRLAGGQRPPQPENLPVPEALDFMNEKNTDG"
     gene            complement(18965..19609)
                     /gene="cheZ"
                     /locus_tag="OPV72_001052"
     CDS             complement(18965..19609)
                     /gene="cheZ"
                     /locus_tag="OPV72_001052"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein phosphatase CheZ"
                     /protein_id="HCR9913418.1"
                     /translation="MMQPSIKPADEGSAGDIIARIGSLTRMLRDSLRELGLDQAIAEA
                     AEAIPDARDRLDYVVQMTAQAAERALNSVEASQPHQDAMEKEAKALTQRWDEWFDNPI
                     ELSDARELVTDTRQFLRDVPGHTSFTNAQLLDIMMAQDFQDLTGQVIKRMMDVIQEIE
                     RQLLMVLLENIPEQSARPKRENESLLNGPQVDTSKAGVVASQEQVDDLLDSLGF"
     gene            complement(19620..20009)
                     /gene="cheY"
                     /locus_tag="OPV72_001053"
     CDS             complement(19620..20009)
                     /gene="cheY"
                     /locus_tag="OPV72_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002210873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis response regulator CheY"
                     /protein_id="HCR9913419.1"
                     /translation="MADKELKFLVVDDFSTMRRIVRNLLKELGFNNVEEAEDGVDALN
                     KLQAGGFGFIISDWNMPNMDGLELLKTIRADSAMSALPVLMVTAEAKKENIIAAAQAG
                     ASGYVVKPFTAATLEEKLNKIFEKLGM"
     gene            complement(20027..21076)
                     /gene="cheB"
                     /locus_tag="OPV72_001054"
     CDS             complement(20027..21076)
                     /gene="cheB"
                     /locus_tag="OPV72_001054"
                     /EC_number="3.1.1.61"
                     /EC_number="3.5.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate methylesterase/protein
                     glutamine deamidase"
                     /protein_id="HCR9913420.1"
                     /translation="MSKIRVLSVDDSALMRQIMTEIINSHSDMEMVATAPDPLVARDL
                     IKKFNPDVLTLDVEMPRMDGLDFLEKLMRLRPMPVVMVSSLTGKGSEVTLRALELGAI
                     DFVTKPQLGIREGMLAYSEMIAEKVRTAARARIAAHKPMAAPTTLKAGPLLSSEKLIA
                     IGASTGGTEAIRHVLQPLPLSSPAVIITQHMPPGFTRSFAERLNKLCQISVKEAEDGE
                     RVLPGHAYIAPGDKHMELARSGANYQIKIHDGPPVNRHRPSVDVLFHSVAKHAGRNAV
                     GVILTGMGNDGAAGMLAMYQAGAWTIAQNEASCVVFGMPREAINMGGVSEVVDLSQVS
                     QQMLAKISAGQAIRI"
     gene            complement(21073..21939)
                     /gene="cheR"
                     /locus_tag="OPV72_001055"
     CDS             complement(21073..21939)
                     /gene="cheR"
                     /locus_tag="OPV72_001055"
                     /EC_number="2.1.1.80"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate O-methyltransferase CheR"
                     /protein_id="HCR9913421.1"
                     /translation="MTSSLPSGQTSVLLQMTQRLALSDAHFRRICQLIYQRAGIVLAD
                     HKRDMVYNRLVRRLRALGLDDFGRYLSMLEANQNSVEWQAFINALTTNLTAFFREAHH
                     FPILAEHARRRHGEYRVWSAAASTGEEPYSIAITLADALGMAPGRWKVFASDIDTEVL
                     EKARSGIYRLSELKTLSPQQLQRYFMRGTGPHEGLVRVRQQLANYVEFSSVNLLEKQY
                     NVPGPFDAIFCRNVMIYFDKTTQEDILRRFVPLLKPDGLLFAGHSENFSNLVREFSLR
                     GQTVYALSKDKA"
     gene            complement(22100..23761)
                     /gene="tar"
                     /locus_tag="OPV72_001056"
     CDS             complement(22100..23761)
                     /gene="tar"
                     /locus_tag="OPV72_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein II"
                     /protein_id="HCR9913422.1"
                     /translation="MFNRIRVVTMLMMVLGVFALLQLVSGGLLFSSLQHNQQGFVISN
                     ELRQQQSELTSTWDLMLQTRINLSRSAARMMMDASNQQSSAKTDLLQNAKTTLAQAAA
                     HYANFKNMTPLPAMAEASANVDEKYQRYQAALAELIQFLDNGNMDAYFAQPTQGMQNA
                     LGEALGNYARVSENLYRQTFDQSAHDYRFAQWQLGVLAVVLVLILMVVWFGIRHALLN
                     PLARVITHIREIASGDLTKTLTVSGRNEIGELAGTVEHMQRSLIDTVTQVCEGSDAIY
                     SGTSEIAAGNTDLSSRTEQQASALEETAASMEQLTATVKQNADNARQASQLAQSASET
                     ARHGGKVVDGVVNTMHEIADSSKKIADIISVIDGIAFQTNILALNAAVEAARAGEQGR
                     GFAVVAGEVRNLASRSAQAAKEIKALIEDSVSRVDTGSVLVESAGETMTDIVNAVTRV
                     TDIMGEIASASDEQSRGIDQVALAVSEMDRVTQQNASLVQESAAAAAALEEQASRLTQ
                     AVSAFRLASRPLAVNKPEMRLSVDAQSGNTPRPLAAGDDANWETF"
     gene            complement(23998..24501)
                     /gene="cheW"
                     /locus_tag="OPV72_001057"
     CDS             complement(23998..24501)
                     /gene="cheW"
                     /locus_tag="OPV72_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HCR9913423.1"
                     /translation="MTGMSNVSKLAGEPSGQEFLVFTLGNEEYGIDILKVQEIRGYDQ
                     VTRIANTPAFIKGVTNLRGVIVPIVDLRVKFCEGDVEYDDNTVVIVLNLGQRVVGIVV
                     GGVSDVLSLTAEQIRPAPEFAVTLSTEYLTGLGALGERMLILVNIEKLLNSEEMALLD
                     IAASHVA"
     gene            complement(24522..26537)
                     /gene="cheA"
                     /locus_tag="OPV72_001058"
     CDS             complement(24522..26537)
                     /gene="cheA"
                     /locus_tag="OPV72_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheA"
                     /protein_id="HCR9913424.1"
                     /translation="MSMDISDFYQTFFDEADELLADMEQHLLDLVPESPDAEQLNAIF
                     RAAHSIKGGAGTFGFTILQETTHLMENLLDEARRGEMQLNTDIINLFLETKDIMQEQL
                     DAYKNSEEPDAASFEYICNALRQLALEAKGETTPAVVETAALSAAIQEESVAETESPR
                     DESKLRIVLSRLKANEVDLLEEELGNLATLTDVVKGADSLSATLDGSVAEDDIVAVLC
                     FVIEADQIAFEKVVTAPVEKAQEKTEVAPVASPAVVAPAAKSAAHEHHAGREKPARER
                     ESTSIRVAVEKVDQLINLVGELVITQSMLAQRSNELDPVNHGDLITSMGQLQRNARDL
                     QESVMSIRMMPMEYVFSRFPRLVRDLAGKLGKQVELTLVGSSTELDKSLIERIIDPLT
                     HLVRNSLDHGIEMPEKRLEAGKNVVGNLILSAEHQGGNICIEVTDDGAGLNRERILAK
                     AMSQGMAVNENMTDDEVGMLIFAPGFSTAEQVTDVSGRGVGMDVVKRNIQEMGGHVEI
                     QSKQGSGTTIRILLPLTLAILDGMSVRVAGEVFILPLNAVMESLQPREEDLHPLAGGE
                     RVLEVRGEYLPLVELWKVFDVDGAKTESTQGIVVILQSAGRRYALLVDQLIGQHQVVV
                     KNLESNYRKVPGISAATILGDGSVALIVDVSALQGLNREQRMAITAA"
     gene            complement(26542..27471)
                     /gene="motB"
                     /locus_tag="OPV72_001059"
     CDS             complement(26542..27471)
                     /gene="motB"
                     /locus_tag="OPV72_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein MotB"
                     /protein_id="HCR9913425.1"
                     /translation="MKNQAHPIVVVKRRRHKPHGGGAHGSWKIAYADFMTAMMAFFLV
                     MWLISISSPKELIQIAEYFRTPLATAVTGGNRIANSKSPIPGGGDDYTQQQGEVEKQP
                     NIDELKKRMEQSRLNKLRGDLDQLIESDPKLRALRPHLKIDLVQEGLRIQIIDSQNRP
                     MFKTGSAEVEPYMRDILRAIAPVLNGIPNRISLAGHTDDFPYANGEKGYSNWELSADR
                     ANASRRELVAGGLDNGKVLRVVGMAATMRLSDRGPDDAINRRISLLVLNKQAEQAILH
                     ENAESQNEPVSVLQQPAAAPPASVPTSPKAEPR"
     gene            complement(27468..28355)
                     /gene="motA"
                     /locus_tag="OPV72_001060"
     CDS             complement(27468..28355)
                     /gene="motA"
                     /locus_tag="OPV72_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor stator protein MotA"
                     /protein_id="HCR9913426.1"
                     /translation="MLILLGYLVVIGTVFGGYVMTGGHLGALYQPAELVIIGGAGMGA
                     FIVGNNGKAIKGTMKAIPLLFRRSKYTKSMYMDLLALLYRLMAKSRQQGMFSLERDIE
                     NPKESEIFASYPRILADAVMLDFIVDYLRLIISGNMNTFEIEALMDEEIETHESEAEV
                     PANSLAMVGDSLPAFGIVAAVMGVVHALASADRPAAELGALIAHAMVGTFLGILLAYG
                     FISPLATVLRQKSAETTKMMQCVKITLLSNLNGYAPPIAVEFGRKTLYSSERPSFIEL
                     EEHVRAVRNPNQQQTTEEA"
     gene            complement(28483..29061)
                     /gene="flhC"
                     /locus_tag="OPV72_001061"
     CDS             complement(28483..29061)
                     /gene="flhC"
                     /locus_tag="OPV72_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar transcriptional regulator FlhC"
                     /protein_id="HCR9913427.1"
                     /translation="MSEKSIVQEARDIQLAMELINLGARLQMLESETQLSRGRLIRLY
                     KELRGSPPPKGMLPFSTDWFMTWEQNIHASMFCNAWQFLLKTGLCSGVDAVIKAYRLY
                     LEQCPQPPEGSLLALTRAWTLVRFVESGLLELSSCNCCGGNFITHAHQPVGSFACSLC
                     QPPSRAVKRRKLSRDAADIIPQLLDEQIEQAV"
     gene            complement(29064..29405)
                     /gene="flhD"
                     /locus_tag="OPV72_001062"
     CDS             complement(29064..29405)
                     /gene="flhD"
                     /locus_tag="OPV72_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310629.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar transcriptional regulator FlhD"
                     /protein_id="HCR9913428.1"
                     /translation="MHTSELLKHIYDINLSYLLLAQRLIVQDKASAMFRLGINEEMAN
                     TLGALTLPQMVKLAETNQLVCHFRFDDHQTITRLTQDSRVDDLQQIHTGIMLSTRLLN
                     EVDDTARKKRA"
BASE COUNT         6813 a         8442 c         7616 g         6965 t
ORIGIN      
        1 tatcgtcttt acctgtatag gtgccgcgct tttcggccag atatccaccg cttcacagtg
       61 ctggagcaac catgttggga ttattattgg tcataatggt gatgactatc tggtggcgga
      121 aagtcgcgtc cccctctcaa ccgtcaccac gctgtcactg tttatacaac gttcagccgg
      181 acaacgttac gcggttcgtc gcctgtgcgg cggcctgacg gtcgagcaga aactcgccat
      241 catggagcag gttcccgccc ggctgaataa gttttatcac acggggttta aatacgagtc
      301 atcgcgccag ttctgctcga aatttgtgtt tgatatctat aaagaagcat tgtgtattcc
      361 ggtaggcgat attgagacat tcgaagaatt acttcacagc aatcctgatg cgaaactcac
      421 cttctggaaa ttctggtttt taggttcaat cccgtgggat cgtaagacgg tgacgcccgc
      481 cagcctgtgg caacatccca atttagaatt aattagcgcc tgtggaattg aaaaccctca
      541 acgcgaggct gagggagaat aatttagcgc aaccttcccc gcgccagatt gagtcggctc
      601 tcgctcattt gcatcgcgtt ctggctaaca tggcaatgcg taatggcgat agccagcgca
      661 tctgcggcgt ctgcctgcgg gttagcgggg agcttcagca acgtacgaac catatgctgt
      721 acctggcttt tctccgcgct accaataccg acgacagttt gcttcacctg acgcgccgcg
      781 tattcaaaca cgggcagttc ctggttgacc gcggcgacaa tcgctacgcc gcgcgcctgt
      841 cccagcttga gggctgaatc ggcattcttc gccataaaca cttgttcgat agcaaaatag
      901 tccggctgga actgcgtgat gatttccgtc acgcctgcgt atatgagctt caaacgagac
      961 ggcaaatcat cgactttggt acgaatacat ccgctgccca gataggtcag ttgtctgcct
     1021 acctggcgga taacgccata accggtaata cgcgagccgg ggtcaatacc gagaataatc
     1081 gacacgctat accccctgcc cgccggcgtt tagcagcacc attacagggt cgccgccacc
     1141 tcatcagaga tctcaccgtt atggtagact tcctgaacat cgtcacagtc ttccagcata
     1201 tcgataagac gtagcagttt cggcgcggtt tccgcatcca tatccgcttt ggttgacggg
     1261 atcatggaca cttcggcgct gtccgctttc agacccgccg cttccagcgc gtcacgcact
     1321 ttgcccatct cttcccaggc agtgtaaaca tcaatcgcgc catcatcata ggtcacaaca
     1381 tcttccgcgc cagcttccag tgcggcttcc atgatggtgt cttcatcgcc tttctcaaag
     1441 gagatgaccc ctttcttact gaacaggtac gccactgagc catcggtacc cagattaccg
     1501 ccgcacttgc tgaaagcatg acgcacttcc gctacggtac ggttacggtt gtcactcaaa
     1561 cactcaatca taatggccgt gccgccagga ccataacctt catagatgat ggtttccatg
     1621 ttcgagtctt catcaccacc cacaccgcga gcgatggcac ggttcagagt gtcgcgggtc
     1681 atgttgttgg ccagcgcttt atctacagcc gcgcgcagac gcgggttggc atccggatcg
     1741 ccgccgccca atttagctgc cgttaccagt tcacgaataa ttttagtgaa gattttaccg
     1801 cgcttggcat cttgcgcagc tttacgatgt ctggtgttgg cccatttact atgacctgcc
     1861 ataaatattt cctcaaaaaa agcgcgcctt ttcaggcgac gttaatgaca aactcttcaa
     1921 tcgcttgccg gttactccag gacttggtaa gcgccgccgc gtcaggcgca tcaagccact
     1981 ggtacgttag atgttcagtg aatatcacct gccgctcatg cggtaacgca aggcagaacc
     2041 agaattctgt attgtgcatg acgcccggcg catagcgatg acgtaaatgt gaaaaaattt
     2101 caaactccac cgtacgttgg cagtcgacta aggtcagttg ctctgccgca acatcaatcg
     2161 tgacctcctc tttgacttca cgcacggcgg tctgcaacgc ggtctcccct tcttctatgc
     2221 tgccagtcac tgactgccaa aaatccgggt cgtcgcgtcg ctgcaacatt agcacccgtt
     2281 tcgtatcctg cgcgaaaata accaccagga ccgaaacggg gcgcttgtac actttatcct
     2341 tcacgcgacc tcgttgttgg ctgttgggtg acgccgcgca ttgatgagac tcccccttgc
     2401 gggccgccgc gatatcacgc gaatgatgtc gtgtacattg ttcatatcag ttattctcgg
     2461 ctttcttcac aacctgaatc cccaactccg tcaacgctgc ctggttggcg aaactcggcg
     2521 cttcagtcat cagacacgcg gcggcggtcg ttttcgggaa ggcgataaca tcacgaatat
     2581 tgtcggtgcc ggtcaacagc atggtcagac ggtccagacc aaacgccagg cccacgtgcg
     2641 gcggcgtacc gtatttcaac gcatccaaca ggaagccgaa cttctcgcgc tgctcctgct
     2701 cattgatacc gagaatacca aatacggttt gctgcatttc accgttgtga atacgcaccg
     2761 aaccgccacc cacttcatag ccgttaatca ccatatcgta agcgttagcg acggcttctt
     2821 ccggggcagt tttcagttca gacgccgtca tgtcacgcgg ggcggtgaac ggatggtgca
     2881 tcgcggtcag accgccttcg ccgtcgtctt cgaacatcgg gaagtcaatc acccacagcg
     2941 gcgcccattt gtcttcgtcg gtcaggctca ggtctttgcc cagtttcaga cgcagcgcgc
     3001 ccagcgcatc ggcaaccact tttttgttat ctgcgccgaa gaagatcatg tcgccgtcct
     3061 gcgcgccggt acgttcaagg atagcctcga cgatgtcggc ggtcaggaac ttggccaccg
     3121 gactgttaat cccgtccaga cctttcgcgc gctcgttaac tttgatatat gccagtcctt
     3181 tcgcgccgta gatcttaaca aagttaccgt aatcgtcgat ctgcttacgg ctaagctgtg
     3241 cgccgccagg cacacgcagc gctgccacgc ggcctttcgg atcgttagcc gggcccgcga
     3301 agaccgcgaa ctctaccgat ttcagcaggt cagcgacatc taccagctcc atcgggttac
     3361 gcaggtctgg cttgtcggaa ccgtagcgac gttccgcttc ggcaaacgtc atgaccggga
     3421 aatcccccag atccacgcct ttcacttcca gccacaaatg gcgcaccagc gcttccatca
     3481 cttcgcgcac ctgtggcgcg gtcatgaagg aggtctcgac gtcgatctga gtaaactccg
     3541 gctgacggtc agcacgtaag tcttcatcac ggaagcattt gactatctga tagtaacggt
     3601 cgaaaccgga catcatcagg agctgtttga acagctgcgg cgactgcggc aacgcataga
     3661 atttaccttt gtgtacgcgg gacggtacca ggtaatcgcg cgcgccttcc ggggtcgctt
     3721 tggtcagcat cggggtttca atatcaagga aaccgtgatc gtccataaaa cgacgcacca
     3781 ggctggtaat tttggcgcga gttttcaggc gctgcgccat ttccggacga cgcaaatcca
     3841 gatagcggta cttgagacgc gcctcttcgg tattaacgtg gttagcgtca agcggcagtg
     3901 agtctgcgcg gttgatgata gtgagagagg acgccagcac ttcaatttcg ccggtcgcca
     3961 tatccgcatt gacgtttttc gcgtcacgcg cacgcacggt gcccgtaacc tgaatgcaga
     4021 actcattacg cagttcagag gccagcttta acgcgtccgc acgatccgga tcgaagaaca
     4081 cctgcacaat accttcgcgg tcgcgcatat cgataaagat caggctgcca agatcacgac
     4141 gacggttgac ccaaccacac agagtcacct gctgccccac gtgggacaga cgtagctgtc
     4201 cgcaatattc tgtacgcatg agatatccct taacttagcc gcaggcggat tgttgcctgc
     4261 catgcaggcg acgaagtcgc agctttagct gtatgtcaca actggatgaa aaaaggcggc
     4321 tattatactg gaaattctgc cgcacgataa gagtcaatcc agcatgggag cgataacttg
     4381 cccgtttcat gcggtatcga cacttggttc atactgactg tacccgggtt tttcacgcgg
     4441 gtattgcgta tgctcacaaa aattaacaat atttgtcgcc gctttcctct ttaatcgcgc
     4501 ttaaggtgta gtgaaatccg ctatttttag gagagtgatt atcatgctga aactcaacgc
     4561 gaccacaacc gccctggtgg ttattgattt acaggaagga attcttccgt ttgccggcgg
     4621 cccgtatacg gcaaatgagg tggtcgcccg cgccgcgcgg ctggcggaaa agtgtcgcgc
     4681 caacggctcg cccgtggtta tggtacgcgt tggatggtct gatgattatg ccgaagcgtt
     4741 aaaacagccg gtggatgccg caacgcctgc gcacgcgttg ccggaaaact ggtggacctg
     4801 gcctacggca ttgggtaaaa aggacagcga tctggaagtg actaaacgcc agtggggcgc
     4861 gttttacggc accgacctgg aattacagct tcgccgccgg ggtatcgaca ccatcatatt
     4921 gtgcggaatc tcaaccaata tcggcgtcga atccacagcg cgtaacgcct gggagttggg
     4981 atttaacctt attattgccg aagatgcctg tagcgccgcc agcagtgagc agcatcagag
     5041 cagtatgacg catattttcc cgcgcattgg ccgggtacgc agcgtagagg atattttaaa
     5101 cgccttatga tctacattgg cttgccgcaa tggtcgcacc cgaaatgggc gcggctcggc
     5161 atcaccagtc tggaagagta tgcccgccac tttaactgcg tggagggcaa caccacgctt
     5221 tacgcgctgc cgaaagcgga aattgtcgat cgctggtatg cgcaaactac ggacgatttc
     5281 cgtttttgct ttaaatttcc cgccaccatt tctcaccagg ccgctctgcg ccattgcgac
     5341 gatctggtac aggcgttttt tacccgcctg gcgccgctgg aaacgcgtat tggccaatac
     5401 tggctgcagt tgcccgccgc ctttggaccg cgcgatctcc ccgccttatg gcagtttctt
     5461 gatgcgctcc ccgccacgtt tacctatggc gtagaagttc gtcatccgtg tttttttgac
     5521 aagggtgagg atgaacagcg gctcaatcgc gggttacacg cgcgcggcgt aaaccgcgtg
     5581 atcctggata gtcgtccggt acatgccgcc catccccaca gcgaggccgt ccgtgacgcg
     5641 cagcgaaaaa aacccaaagt cccggtacat gcggtcgtga cggccagcca tccgatggtg
     5701 cgttttatcg gtagcgataa tatggcgcaa aaccgtgagt ttttcgctgc ctggttgcag
     5761 aaactcccgc agtggcggca gaccaccacg ccttttctgt ttttacatac tccggatatc
     5821 gcgcaggcgc cggaactggt gaatacgctt tggcatgatt tacgcagcgt cttaccggaa
     5881 atcggcactg ctccgtccat tccacagcaa tcttctcttt tctgaaaatg ccccctatca
     5941 tagacagtgc catcagccat tttaaaaggg agtttgtatg gtaagcgcgc tgtatgccgt
     6001 tttgggtgcg ttattattaa tgaagttctc ttttaatgtc gttcgcttac gaatgcagta
     6061 ccgtgtcgcc tatggcgacg gcggttttag cgaattgcaa agcgccatcc gtattcatgg
     6121 caacgcggtg gaatatattc ctgtcgcgct ggtgctgctg ctgtttatgg aaatgaacgg
     6181 cgccgaaacg tggatggtgc atatctgcgg catcatttta atcgccggtc ggctgatgca
     6241 ttattacggt tttcaccacc gcctgttccg ctggcggcgg gcggggatga gcgcgacctg
     6301 gtgcgcattg ttgctgatgg tgctggcaaa cctgtggtat atgccctggg agttggtttt
     6361 ctccctgtat tagcgcacaa tatgcgcctt tatttttccc ggatgtatac gttatgtctc
     6421 accgcgacac gcttttttct gcgcctatcg cccgtctcgg cgactggact tttgatgaac
     6481 gagtagccga agttttcccc gacatgattc agcgttcggt accaggctac tccaacatca
     6541 tctccatgat cggcatgtta gctgaacgct ttgtgcagcc gaacacgcag gtctacgatc
     6601 tgggctgctc gctgggtgcc gcgacgctgt ctgttcggcg taatatccgc catgagcatt
     6661 gtcgcattat cgccgtcgat aactccccgg ccatgattga acgctgccgc cgtcatattg
     6721 atgcgtataa agcgcctacg ccggttgaag tcgttgaagg cgatatccgc gatatcacta
     6781 ttgaaaacgc ctcgatggtg gtgctgaatt ttaccctaca attccttgaa cctgccgaac
     6841 gccaggcatt gctggataag atttacctgg ggttgaatcc cggcggcgcg ctggtactgt
     6901 cggaaaaatt tagctttgaa gacgcgaaag tgggcgagct gttattcaac atgcaccacg
     6961 attttaaacg cgctaatggg tacagcgaac tggagatcag ccaaaagcgc agtatgctgg
     7021 aaaacgtgat gctcaccgac tcggtggaaa cacataaagc gcgcctgcgt caggcgggtt
     7081 tcgaacacag cgaactgtgg ttccagtgct ttaacttcgg gtcgcttgtc gcgttaaaag
     7141 ccggagttgc cgcatgatcg agtttggtaa cttttatcag ctcattgcta aaaatcatct
     7201 ctcccactgg ctggaaacat tgcccgcgca gattgccgcc tggcaacgcg agcagcagca
     7261 tggcttgttt aaacagtggt cgaacgcggt agaattttta ccggaaatta cgccctggcg
     7321 gctggattta ctgcacagcg tcacggcgga aagcgaaacg ccgctcagcg aaggtcagct
     7381 aaagcgtatt gatacattgc tgcgtaatct gatgccgtgg cgtaaaggcc cgttctcgct
     7441 ttatggcgta gatattgata ccgaatggcg ctcagactgg aagtgggatc gcgtactgcc
     7501 gcatctgtca gatttaaccg gccggacgat ccttgatgtc ggctgcggca gcggctatca
     7561 cctgtggcgg atgattggcg cgggcgcaca tctggcggtc ggcatcgatc ctacacagct
     7621 tttcctctgc caatttgagg cggtgcgtaa actgttgggt aacgatcagc gcgcgcatct
     7681 gctgccgttg ggcattgaac aactcccggc gctgaaagca tttgataccg tcttttcaat
     7741 gggggtgctt tatcaccgtc gctcgccgct ggagcatctg tggcaattaa aagatcagtt
     7801 ggtcaacgag ggtgagctgg tactggaaac gctggtcgtc gacggcgacg aaaataccgt
     7861 actggtgccg ggtgaccgct acgcgcagat gcgtaacgtc tattttattc cttccgcgcc
     7921 ggcattaaaa aaatggctgg aaaaatgcgg ctttgttgat gtgcgtatcg ctgacgtttg
     7981 cgtcactacc accgaagagc agcgccgtac cgaatggatg gttaccgagt cgctggccga
     8041 ttttcttgac ccgaacgatc gcagcaagac ggtggaaggc tatcccgccc cgcagcgcgc
     8101 ggtgctgatt gcgcgtaaac cgtgatggat tgccgaatga ccgttacgta tagcaccgtt
     8161 tctccaaaat agttcaagtt gcagcaaggc ggcaacgcag caaatccccg ggaacgtagg
     8221 tagctacgtg accggggtgc gcgaggcggc caacgctgct gcggcttgaa atatgaagga
     8281 gaaaaaaagg cccctgttga attggcaggg gcctggtacg agcaagcatc atattgggcg
     8341 acatgatgca acggtaaaaa tcatttggcc tgatggcgaa caatgattcc tttcattctc
     8401 agcgaccgcc gcaccctcta ccctatagcg agaatactcg tccgcctgta tatcggcaga
     8461 catcgataac ccctgattgc gatagcgcat cggcgaaggc agtaagactc cggcggaact
     8521 gtgtacttcc cgtactccgg catcgaggaa attctgcagg ttatttgcac gaacccccgc
     8581 accagccata atgattggag catccccctg ggcaataagt tccataatta ttgataaacc
     8641 ttgcgccgca tcggcttttt gcccggaagt cagtactctt gctacgcctg cgtcagccag
     8701 attctttagc gcattgaagg gattagcgca catatcgaag gcgcggtgga atgtcaccgc
     8761 cagcggcccg gccgccgcca ttattttttc cattcgcgac atatcgacat ccccatcaac
     8821 ggtcaacacg ccagtaacca gcccgggaaa ccccaactct ctgacgagac ggatatcttc
     8881 cagcatggcg gcaaattcgc cgtcagtgta gtaaaaatct ccgccgcgag gacgaataat
     8941 cggatgtacg ggaatcgtaa tatgctcgcg tacgctgcgt aagatgccga aagaaggcgt
     9001 aagcccccct tctttcggcg cggcgcacag ttcgatacga tccgcgccgt ttcgctgcgc
     9061 ggtgagcgcg cattccatgc tgtaacaaca gatctcaagt aacgccatat tcactccgct
     9121 cggcaggtta atgggccgcc tgttcgctgg cgacaatcgc ttcaatcgac catggatgaa
     9181 attttaccgt gacgcggcca tcggtcacag ccagcgtagg gtttggcaaa cgttcatgct
     9241 cgccctgtgg cgaactggtt ttaaccacga tccccggctg actaagcccc tcatccgaca
     9301 acaacgccag ggccctcgcg ttcaaggtct ccggctcgcc gggcagcacg atttcaatat
     9361 gctcccaccc ttcgtgtgga tagcgttttt ctcccggcca cggtaattca ataacagaaa
     9421 accgccagtg ttccacacat accggttcat gcagtttaaa cagacaaatc ggcctgccgt
     9481 tgatgatatt ttccgacagt agctcgccgc attgttcaaa accgcgacgc caacgctccg
     9541 ccgtcgtatt ctggtgacag cgcaatgaaa tgtgatcggc ctcaagggcg ttaatctgca
     9601 gaccaaggcg agtggaaagt tctctgaacg ccagagtgaa tcgcggtaaa tctgcggaaa
     9661 tatcatgcag ttcatcaatg tgttgccagt tcgccatatc aggacgctct tcttgctgtg
     9721 aaaaccgcta atttacgctg ttgcgccccg gcaaccaacc tttgatttga ttgggcgttt
     9781 attgaatgct tatgcagatt attgttgcgt atatttcagg cgacgcgccg cgcgcgcaat
     9841 gctgacgcca acgggcattt gcagtatact cccgccctaa ttcttaaact ggcgcgggca
     9901 atacagtccg cttcataaac gtaaggtatt ccggtgaata ttcaggctct tctctcagaa
     9961 aaagttagtc aggccatgat tgctgcaggc gcgcctgcag attgcgagcc ccaggttcgt
    10021 cagtcagcca aagttcagtt cggcgactat caggccaacg gcatgatggc agttgcgaaa
    10081 aaactgggta tggccccccg acaacttgca gagcaggtgc tgactcatct ggatctcagc
    10141 ggcatcgcca gcaaggttga aatcgccggc cctggcttta tcaatatttt cctcgaaccg
    10201 gcttttctcg ctgaacaggt gcaacaggcg ctgacctccg atcgtctggg cgtttctcag
    10261 ccgactcgcc agacgattgt cgtcgactac tccgcgccca acgtcgcgaa agagatgcac
    10321 gttggtcatc tacgctccac gatcattggc gatgcggcag tgcgcacgct ggagtttctg
    10381 ggccatcatg ttattcgcgc taaccacgtc ggcgactggg gcacccagtt cggtatgctt
    10441 atcgcttggc tggaaaaaca gcagcaggaa aacgcgggcg acatggcgct ggcggatctc
    10501 gaaggatttt accgcgatgc gaaaaaacat tatgacgaag atgaaacgtt tgccgagcgc
    10561 gcgcgtaact acgtcgtcaa attgcagagc ggtgatacct atttccgtga gatgtggcgt
    10621 aagctggttg atatcacgat gacgcaaaac cagatcacct atgatcgtct gaacgtcact
    10681 ctgacgcgtg acgatgtgat gggcgaaagt ctgtataatc cgatgctgcc gggcatcgtc
    10741 gccgatctga aagccaaagg cctggcggtt gaaagcgaag gcgcaacggt ggttttcctt
    10801 gatgagttta aaaacaagga aggcgacccg atgggcgtca ttattcagaa gaaagatggc
    10861 ggttatctgt ataccactac cgatatcgcc tgcgccaaat accgttacga aacgctgcac
    10921 gccgaccgcg tgctctacta cattgactcc cgtcagcacc agcacctgat gcaggcctgg
    10981 accattgtgc gtaaagccgg ttatgtgccg gattccgttc cgctggaaca ccacatgttc
    11041 ggcatgatgt tgggtaaaga cggtaaaccg tttaaaactc gcacgggcgg tacggtgaaa
    11101 ctggcggacc tgctggatga ggcgctggag cgcgcgcgtc gtctggtggc ggagaagaac
    11161 ccggatatgc cggctgacga gctggaaaaa ctggctaacg ccgtcggtat tggcgcggtg
    11221 aaatacgccg atctgtcaaa aaaccgcacc actgactata tcttcgactg ggataatatg
    11281 ttggctttcg aaggcaatac cgcaccttat atgcagtatg cctatacgcg tgtgctgtct
    11341 gttttccgta aagcggacat cgacgagcag gcgctggcga gcgcgccggt tatcattagc
    11401 gaagatcgcg aagcgcagct cgctgcccgt ctgctgcagt ttgaagaaac cctgacggtg
    11461 gtcgcgcgtg aaggtacgcc gcacgtcatg tgcgcgtatc tgtatgacgt cgccgggctg
    11521 ttctccggct tctacgagca ctgccctatt ctcagcgccg agaatgacgc ggttcgcaat
    11581 agccgcctaa aactggcgca actgacggcg aagacgctga aactgggtct ggatacgttg
    11641 ggtatcgaaa ccgtagaacg catgtaaacg cgccgtcgtt aacatcatca ggcctgactc
    11701 cgggtaacgg actcaggcct ttttattgcc acagcggtat atctgtaaca aatcacaagg
    11761 aatgacacat ttctatagag agatggaaca tcttttacct gtgctggcgc tgaccgcccc
    11821 gtatcattag gcggcggatt gttcaggtac aggtaatgac ttttaaagac tttgatgcgg
    11881 aagagaaact cttcctgaga cgtgtgattg tggcgtttgg tgtagtggtt gtctgctttg
    11941 gtatcctgat cttcaacctc tataacttgc aaatccgcca gcaccactac tacaccaccc
    12001 gttcgaatga gaacgatatc aagatgctac ccgtcgcgcc cacgcgcggc atcatttacg
    12061 atcgcaacgg cattccgctg gtgcgtaacg taacctggta tgatatcgcg gttacgccct
    12121 ataaaattgc cgatatggat gcgctgctaa aacagctcac ccctattgtt gatctctccc
    12181 ccgacgatat cgccgacttt cgccgcgcgc taaaatccag tagccgctat cgtccggtag
    12241 tgctcaaaaa cgcgctaacg gatgttgaaa tcgcacgctt tgcggtcaat cagtttcatt
    12301 tcaacggcgt cacgatcaat agctatcagg atcggcagta tccttacggc gcggagctgg
    12361 cgcatgttct cggttacgtg tcaaagataa acgataacga ccttaaagcg ctggataaaa
    12421 aagggctggc agagaattac gcggcggacc ataacatcgg taaacagggg attgagcgtt
    12481 actacgaaaa cgatcttcat ggcaaaaccg gttatcagga ggtcgaggtg gataatcacg
    12541 ggcgtattgt ccgcctgctg aaagacgttc ctcccatcgc gggtaagaac attcacctga
    12601 cgttggatct ccatttacaa gagtacattg aaagtttgct ggccgggcag cgtgctgccg
    12661 tactggttga agatccgcac gatggttcag tgctagcgat ggtatctatg cccagctacg
    12721 acccgaaccc ctttgtaaaa ggcattagct atcaggatta cggcaaactg ctgcacgata
    12781 aaaatctgcc gctgatcaac cgcgtgacgc aagggcttta tcccccggcg tcaacggtta
    12841 aaccctatat ggcgatgtcc gcgctgttat gcgggattat tacgccgcaa accaccttct
    12901 ttggcgcgcc aacctggacg cttcccggca cgcagcgtca ttaccgggac tggaaaaaaa
    12961 ccggacacgg tatgctggat gtcactaaag cgattgagga atctgcggat acctttttct
    13021 attaggtcgc ttatatgatg ggtattgacc gtatcgacac gatgttgtct cagttcggct
    13081 atggcaaacc gacgggtatc gaccttagtg aagagtatga cgggctgctt cccagccgcg
    13141 catggaaaca gcgggtccat aaaaaagcct ggtatcaggg cgataccatc tctgtcggca
    13201 tcggccaggg ctactggatt gccaccccca tccagatggt aaaagcgatg gtggcgctca
    13261 tcaacaacag taaggtgatt gcccctcacc tgttactcaa tgaagagagc ggcaaaacgg
    13321 tggttccgta tcgtccttca ggaacaccgg cacagatagc cgatccggcg tcgccatact
    13381 ggggactggt gcgtcaggcg atgtacggca tggcgaatgc acccaacgga acgggctata
    13441 agttctttca caccgcgccc tacggcattg cggccaaaag cggcacgtcg caggtgttta
    13501 gcctgaaaga aaatcagacc tacaatgcga aaatgatccc cattcgcctg cgcgatcatg
    13561 tgttttatac cgcttttgca ccgtataaaa accctaaggt cgctattgcc ttgattctgg
    13621 aaaacggcgg aagcgacggc gttaccgccg cgcccatcat gcgaaaaatc cttgaccacc
    13681 tgtttgatcc acaggctgat accacacagt cgggtcaggc gccatagtca aataagcaaa
    13741 gcgccatcag acaaggatac gaccggaata tctgcataca tcagaaatag ttacgcagat
    13801 attccgtcaa acacagcatt gccatcgcct gcccgtaagg catagaggtc aacggaatat
    13861 gacggtaaaa atcgagatcg tggcccatgc cagtgccaaa tgatgtttgc agcagttcgc
    13921 cttccggcga gatatgtttc actatccccc gaatagcttt ttccgccacc tgcgcatagt
    13981 gccgttcgac atagcgtttg cgcaccgctt taagaatacc gtaggcaaaa cccgccgtcg
    14041 ccgacgcctc aagataagag tgcggatcgt caagcagcgt atgccacaaa ccgctttcat
    14101 cctgacattt cgccagcgcg gcgatctgcg cattcagtac ctggaccaga taacggcgca
    14161 cggcattatt ttccggcaag tccagcagtt caagaaaatc cgggaccaca atggtcagcc
    14221 agctgttgcc gcgcgcccag cgagcgttag cgaagttatg atgaccgtca tagctccagc
    14281 cgtggaacca cagccccgtc tctttatcca tcaaattctg cacgtgtagc aggaactgat
    14341 aggttgcctc ttccacatat tccggccggt tcaacagctt accgattttc gccagcggca
    14401 gcaccgtcat cattagcgtg tcgtcccaca tctgctgatg attttcctcc gccagcgtga
    14461 tgtgctgcat tccgccgtaa tcggtacggg gcatttcatt catcgcccat tcggcccacg
    14521 tttccagcca cggtaaatac gctggattac gcgtctcttc atagcgatac gccagcgtta
    14581 aaaacggcgc catcgtatta acgtttttcg tcgtcgcgcc ttccgcaaag cgatcggcaa
    14641 accagtcatc aatgatctta cgcatcgtct ggtcgccggt ctgttggtaa tagtgataca
    14701 ttccgtacag gcccacgccg tgcgtccact cccatccggc ccagccttta gtatcgatca
    14761 cgcgtccgtc gtccagtcgc aataaaaatt cgcctgtctc atctttaata ttgaccaggt
    14821 tatgcgtcac cttttgcacc agggctttta gttcatctct ggcgataaaa tgctcaggct
    14881 gacgcaatag cggactgtgt ttgactggat aaaccatcat ttgcttaacc tctgtgtaat
    14941 gtcgaattca gtgctgcgtg cagttttacc gccgacgcag tcgattcgct acagtaaaag
    15001 ctaagctggg cggaaacctt tttgtttctg ccattgtcag agcgtaaatg gcaaaaacgc
    15061 aaagagtccg gcaacctacc tcaccatttt ataaaacgac gtttctattt attcaaaaag
    15121 agagtcaggt ctgctacctg gcaaagaaag gggcggttag cggtagttca caatcacctg
    15181 attgctccgc acttttaacg ccgggataag tctgccgccg ccggggactt cccagacaaa
    15241 gcggagcggc tcgactgcgg gaacatgagc aaaaccgtgg gtcgtgccac tctgaccatc
    15301 aagttctacg caacgggact gggaacataa acgtacccgt aatcctgcgg gggtcgggcc
    15361 attcagttca taacgccagg cgaccagcgt catcacaccg gaaaccggct ggcgcgccga
    15421 caatggcgaa gacgatgcgg aaacgccccg gtaatttaag gttacgccca taccgctatc
    15481 ctgccacgcg ccttcgcctg cggcctgaac cgttagggga aagagcaaca atgccagcca
    15541 tttacgcatt attttcctcc aatggtcgcc gtcatgcgga tatgacggtt atcggaaagc
    15601 tcaaggttcg acaacaccac cagctgcggt aaactgcgcc gcaaaaagcg ggacaataat
    15661 ggacgtagcg catggttaac cagtaatacc ggcggcgcgc caagcatttc ctggcgagaa
    15721 agtgcctctt gggtctgcgc cagcaggcga tccgccaacc caggctcaag tccaccgccg
    15781 ccctgcaatg cctgaagcag caaacgctcc agcgcggtat ccaggccaat cacctgcact
    15841 tcttcattac cggggaacca ctgttgcgta atcgctcgcc ctaatgccac gcgtaccacg
    15901 gcggttaatt catgcggatc gctttgtaac ggcgcatgtt ccgccagcgt ttccagaatg
    15961 gtgcgcatat cgcgaatagg gactttttcc gccagtaagt tttgcaggac tttgtgtaaa
    16021 gtcgtgaggg tcacgacgcc ggggaccaga tcttccgtga gtttaggcat ctcctgagag
    16081 acacgatcca acagttgctg cgcttcctgg cggccaaaca gttcggcgga gaattggcca
    16141 atcaagtggt taaggtgcgt cgccacaacg gtactggctt ccacgacggt aaagccctga
    16201 atttgcgcct gctctttcag ggcgctttca atccagatgg catcaaggcc aaaagctgga
    16261 tcgacggttt tctcgcccgg tagcgttccc gccgccgtgc cggggttaat agccagccag
    16321 cgtcccggat aggcgtcccc gctgccgatc tctacccctt tcatcaaaat acggtagcgc
    16381 gcaggctgta aatccatatt gtcgcgaatg tggaccaccg gcggcaggaa ccccatatcc
    16441 tgcgcgaatt ttttacgaat actgcgaata cgtccgagca attcgccatc ctgttgaaaa
    16501 tccaccatcg ggatcaggcg gtagcccact tccattccca gtgaatcctc aagctgtacg
    16561 tcattccagg tggcttcgac caccgagtta ttttccggca tttttaccgg ctgcggctcc
    16621 tccggcgctt tttcttcacg cccgcgcagc caccatgcca ggccgagcaa agcggcggta
    16681 aagagtaaaa ataccaggtt aggcattcca ggcaccatgc caagcagccc cagcaccgcc
    16741 gccgccagca gcattaccct tggattactg aacagttggc caaccatctg ctcgcctaca
    16801 tcctgatcgg tactgacgcg ggtcacaatg acgcccgccg ccgtggagat aaccagcgcc
    16861 gggatctggg cgaccaggcc gtcgccaatg gtcagcaggg tgtagctttc cgccgcgctg
    16921 cccatgctca ttccgtgctg taatacgccg accagcagcc cgcctaccac gttaatgacc
    16981 atgatgagaa taccggcgat ggcgtcgccg cgtacaaatt tacttgcccc gtccatcgaa
    17041 ccgtagaagt cggcttcctg agtgacttcc gaacgccgtt ttttggcctc gtcttcacca
    17101 atcagaccgg cattaagatc ggcgtcaatc gccatttgct taccgggcat accatccagc
    17161 acaaagcgcg cgccgacttc ggcaatacgt ccggcacctt tggtgatgac catgaagttg
    17221 ataatgacga ggatgataaa aaccacaatc ccgatcgcga agttaccgcc gaccaggaaa
    17281 tgaccgaacg cctctaccac ctttcccgcc gccgccgcgc cggtatgccc ttccatcaaa
    17341 ataatgcgcg ttgaggcaac gttaagcgcc agacgcagta gcgtggtaaa cagcaggatg
    17401 gtcggaaacg cggcaaaatc cagagtacgc tgggtaaaca tcgccaccag cagcaccatg
    17461 atcgatagcg caatattaaa ggtaaacaat aagtcgagga taaaagcagg tagcggcagc
    17521 accatcatcg acaaaatcag cagaatgagg atcggcccgg caagaatttg ccattgcgtc
    17581 gatttcaggt tgctgggcag gcgcagcatc gcgaccagat tagccatcag tattcttctc
    17641 gttcataaaa tccagcgctt ctggcaccgg aaggttctca ggttgtggag gacgttgccc
    17701 gcccgcaagc cgccagcgtt taagctgcca gacccaggcc aacacttccg caacggcagc
    17761 atataactgc ccgggaattt gctgaccgat ttcggcgtgg cgatataatg cccgcgccag
    17821 cggcggcgct tctaaagtgg gaacccgatg ttcagcgccg atctcgcgaa tgcgcagcgc
    17881 tattaatcca gcccccttcg cgaccacttt cggcgcgctc attttgtttt cgtcatactg
    17941 cagcgccacg gaatagtgcg tcgggttagt gacaatgacg tccgctttcg gcacatcttc
    18001 catcatgcgg cgctgcgcgg cggcgcgttg catctggcga attttgccct taacatgcgg
    18061 atcgccttcg ctctctttaa attcgtcgcg aatgtcctgc cgcgacatgc gtaatttttt
    18121 caggtggcta aagatctgga aaaaaacgtc aaatcccacc atcgggatca cgcccagtac
    18181 caccagtaac gcgcagagtc caaccagatc cagcgcattc cccattgcga cgatcggcga
    18241 ctccgccatc aggcgcatca tttgcggcca gtgattccag agataaaagc cggtaacgca
    18301 gccgaccagc gtggatttca acaccgcttt tagcagttcc gcgccggtct gcgccgaaaa
    18361 catgcgctta attcccggca gcgggtttaa tttagaaaat tttggctgta gcgacttacc
    18421 gctaaaaatc aggccgccaa gcataaccgg cgagataagc gccaccagca ccacgcccgc
    18481 gatgagcggt agcagtgcca tcatcgccgc tttaatcagc aaaattatct gccccaggat
    18541 caggttagga tcgttcacca tacggtgatc gaagtgcagg cctgctgaga gcattcccgc
    18601 cagctgccgc gctaacgact cgccgccgaa ccaaataata caaacgccca ccagcaatat
    18661 cagcagtgag gtcagttctc tggaacgggg gatctgccct tcttcccgcg ctttttcaag
    18721 tcggtggggt gtgggggctt ctgttttgtc gtcgtcgctc tcttctgcca cgcagcaaac
    18781 cctggataga ttgataagcg agaatgatgc cagaaccgct ttacgccaat gggcagagta
    18841 agcggtaaaa aaggcggggt ttatggcgtt aatagagata gccggatacg ataagaaagt
    18901 atcgtatccg gccgggttga cggattcgga cccgataagc gcagcgccat caggtcaaaa
    18961 aagcttaaaa gccaagactg tccagcaggt cgtccacctg ctcctgactg gcgacgacgc
    19021 cagctttcga ggtatccacc tgcgggccgt tgagcaagct ttcgttctcg cgttttggtc
    19081 gcgcgctctg ttccgggatg ttttccagca gcaccattaa caactggcgc tcaatctcct
    19141 gaatcacgtc catcatgcgt ttgatcacct gacccgtcag atcctggaaa tcctgtgcca
    19201 tcatgatgtc cagcagttgc gcgttagtaa agctggtatg gcccgggaca tccctgagaa
    19261 actggcgcgt atccgtcacc agttcacggg cgtcggaaag ctcgatcgga ttgtcaaacc
    19321 actcgtccca acgttgggtt agcgctttcg cctctttttc catcgcatcc tgatgcggct
    19381 gcgaggcttc gacactgttt agcgcgcgtt ccgccgcctg cgccgtcatc tggacgacat
    19441 aatccagacg gtcgcgcgca tcagggatcg cctccgccgc ttcggcaatc gcctggtcca
    19501 gccccagttc acgcaggctg tcgcgcagca ttcgggtcag actaccgatg cgcgcaatga
    19561 tgtctcctgc tgagccttca tcagcaggct tgatagatgg ttgcatcatc atcgcatcct
    19621 cacatgccca gtttctcaaa gattttgttg agcttctctt ccagagtcgc tgcggtgaac
    19681 ggttttacga cataaccgct ggcgccagcc tgtgcggcgg cgataatatt ctctttcttg
    19741 gcttccgccg tgaccatcaa cacgggtaac gccgacatgg cgctatcggc gcgaatggtt
    19801 ttcagcagct ccaggccatc catgttcggc atgttccagt cagagataat aaaaccaaag
    19861 ccgcctgcct ggagcttgtt cagcgcatcg acgccgtctt cggcctcttc cacattgtta
    19921 aatccaagct cttttaagag gttgcgcacg atacgacgca tggtcgaaaa gtcatccaca
    19981 accaaaaatt taagctcttt atccgccata aaatactact cctggttcaa atacgtatcg
    20041 cctgtccggc actgattttc gccagcatct gctggcttac ctggctaaga tcgaccactt
    20101 cgcttacgcc acccatattg atggcctcgc gcggcatgcc gaacaccaca caacttgctt
    20161 cgttttgcgc aatggtccag gcgccagcct ggtacatcgc taacattcca gcggcgccat
    20221 cgttgcccat ccccgtaaga atgacgccta cggcgttgcg ccccgcgtgt ttcgccaccg
    20281 aatgaaacag cacatccacg gaaggccgat gccggtttac cggcgggcca tcatgaattt
    20341 tgatttgata attcgccccg ctacgcgcca gctccatatg cttgtcgccg ggcgcaatgt
    20401 aggcatgacc tggcaatacg cgttcgccgt cctccgcctc cttcacgctg atttgacaga
    20461 gtttattcag gcgctcggca aacgagcggg taaagccagg cggcatatgc tgcgtaataa
    20521 tcactgccgg actggaaagc ggcagcggtt gcagcacatg tcggatagct tcagtaccgc
    20581 ccgttgaagc gccgatagca atcagttttt ccgaactgag cagcggaccg gcttttaagg
    20641 ttgtcggggc cgccatcggt ttatgtgcgg cgatgcgggc ccgcgcggcg gtacgcactt
    20701 tttcggcaat catctcgcta tacgccagca taccttcacg aatgccaagc tgcggtttgg
    20761 tgacaaaatc gatggccccc aactccagcg cccgtagcgt cacttcggaa cctttcccgg
    20821 tcagcgaaga gaccatcacc accggcatcg gtcgcaggcg catcagtttt tccagaaaat
    20881 cgaggccgtc catacgcggc atctcaacgt ccaaggtcaa tacgtccgga ttaaattttt
    20941 tgatgagatc cctggcgacc aacgggtccg gcgcagtcgc taccatctcc atatcgctat
    21001 ggctattaat aatttcagtc atgatttggc gcattagcgc ggaatcatca actgacaata
    21061 ccctgatttt actcatgctt tatccttact tagcgcatac accgtctgtc cgcgcaggct
    21121 aaactcgcgc acgaggttgc taaagttttc tgagtgaccg gcaaacaaca gtccgtcagg
    21181 tttaaggagt ggaacaaaac ggcgcagaat gtcctcctga gtcgttttat caaaatagat
    21241 catgacgtta cggcaaaaaa tcgcgtcaaa gggaccgggt acgttgtact gcttttccaa
    21301 taaattaacg gaggaaaatt caacataatt ggccagttgc tgacgcacgc gcaccagtcc
    21361 ttcatgcggc cccgtaccgc gcatgaagta acgttgtagc tgctgcggcg ataacgtttt
    21421 cagttcgctg aggcgataaa taccgcttct cgctttttcc agcacttcag tatcaatatc
    21481 gctggcgaat actttccagc gaccgggggc catccctaac gcatccgcca gcgtaatggc
    21541 gatactgtaa ggttcttctc ctgtcgatgc cgccgcactc cagacgcggt actcgccgtg
    21601 gcggcgacgc gcatgttccg caaggatggg aaaatggtgc gcctcgcgaa aaaaagcggt
    21661 caggttggta gtcagagcgt tgataaaagc ctgccactca acgctgtttt gattagcctc
    21721 cagcatactg agataacggc caaaatcatc cagtcccagg gcacgcagcc gacggaccag
    21781 gcggttataa accatatccc gcttatggtc ggccagcacg atccctgcac gctggtagat
    21841 taattgacat atccgacgaa aatgcgcgtc ggacagcgcg aggcgctgtg tcatctgtaa
    21901 caatactgac gtttgcccgg agggcagaga tgatgtcata gcgccttctt aatcacattc
    21961 aaagtacaac gggcgcgccc tgcggcagcg ccatgcttcc cgtattacac attttttgct
    22021 tttatctatg cgaaccagac gaaagggatc ggcgggttcg caaattaatc gataaccgac
    22081 agcacacagc gcacatcgat cagaaggttt cccagttcgc atcatccccg gcggctaagg
    22141 gccgcggcgt attgccggac tgagcgtcca ctgataaacg catctcaggt ttatttaccg
    22201 ccagcggtcg cgatgccagg cggaaagccg ataccgcctg ggtcagacgg ctggcctgct
    22261 cttccagcgc ggcggcggcc gctgcggatt cctgaaccag cgaggcgttc tgttgcgtta
    22321 cgcgatccat ttcggaaacg gccaaagcga cctgatcgat accccggctt tgctcatccg
    22381 aggcggaggc gatttcgccc atgatatccg tgacgcgcgt aacggcattg acgatgtcag
    22441 tcatggtttc cccggcgctt tccaccagca ctgaaccggt atcgacacgc gagacggaat
    22501 cttcaatcaa cgcttttatt tctttcgctg cctgggcact gcggctggcc agattacgca
    22561 cctcgcctgc cacgaccgca aaaccgcgcc cctgctctcc cgcgcgcgcc gcttctaccg
    22621 ccgcgttcag cgccagaatg ttagtctgga aggcaatacc gtcgataacg ctgataatgt
    22681 cagcgatttt tttcgaactg tcggcaattt cgtgcatagt gtttactacg ccgtcgacca
    22741 ctttgccgcc atgacgcgcg gtctcggagg cgctttgcgc cagttgcgaa gcctgacggg
    22801 cattatcggc gttttgcttc acggtggccg tcagttgttc catgctggcc gccgtctcct
    22861 ccagagcgga ggcttgttgt tcggtacggg aagagaggtc ggtattaccg gcggcaattt
    22921 cactggtgcc ggaataaatc gcatccgaac cttcacaaac ctgcgtcacg gtgtcaatca
    22981 gcgagcgttg catatgttca accgttcccg ccagttcgcc aatttcatta cgtcctgaga
    23041 cggtgagcgt tttcgtcaga tcgccgctgg caatttcacg gatatgagta atcactcgcg
    23101 ctaatgggtt aagcaaggca tgacgaatgc cgaaccaaac caccatcaaa atcagcacca
    23161 gcacgaccgc aagaaccccc agttgccatt gcgcaaaacg gtagtcatga gcactttgat
    23221 caaatgtctg gcggtacagg ttttcgctca cccgggcgta attgcccagc gcctcgccca
    23281 acgcgttttg cattccctgg gttggctggg cgaagtaggc atccatattg ccattgtcca
    23341 gaaactgaat aagttcggct aatgcggcct gatagcgctg atatttttca tcgacgttcg
    23401 cgctggcctc cgccatcgct ggcaatggcg tcatgttttt gaaattggcg tagtgcgccg
    23461 ccgcctgtgc gagggtcgtt tttgcattct ggagtaaatc cgttttggcg ctgctctgct
    23521 ggttagaagc gtccatcatc atgcgtgcgg cggagcggct caggttaatg cgcgtttgca
    23581 gcattaagtc ccatgtcgac gtgagttcgc tttgttgctg gcgtaattcg ttagaaataa
    23641 caaaaccttg ctggttatgc tgtaatgaag aaaacagcaa accaccggaa acaagctgta
    23701 gcagtgcgaa aacccccagc accatcatca gcattgtgac aacgcggata cggttaaaca
    23761 taaggcacct tcctgataac gagttatcaa cgttatcggc acctgcggtg ataactttac
    23821 ttttgcaaaa aggaaatacg ctgttccgga agacgacatt gccaatgaca gtgtcgcagc
    23881 ggcgatgccg gcgcaaaatg caggggctgg gcgcgggcga tgaagaggca ctctcaccgc
    23941 tggcggaagc ataacggtga atattgccgg atggcgcgac gccatccggc aacgttatta
    24001 cgcgacgtgt gatgctgcga tatccagcag cgccatctct tcgctgttaa gcagtttttc
    24061 gatattcacc agaatcagca tacgctcgcc gagcgcgccc aatcccgtca aatattctgt
    24121 tgacaaggtc acggcaaatt ctggcgccgg acggatctgt tccgccgtta acgacagtac
    24181 gtcagacacg ccgcctacca ctatcccgac gacacgttgc cccagattca gtacgatcac
    24241 taccgtattg tcatcatact caacgtcgcc ttcgcagaat ttcacgcgca gatcgacaat
    24301 ggggacaatc acgccgcgca ggttagtcac cccttttata aaggccggtg tattggcgat
    24361 gcgcgtcacc tggtcatagc cacggatctc ctgcactttc aggatatcga tgccgtactc
    24421 ttcatttccc agtgtaaaca ccaggaattc ctgacctgac ggctcgccgg ccagtttgct
    24481 tacattactc ataccggtca tattattccc ttctcactca atcaggcggc tgtgatcgcc
    24541 atacgttgtt cgcggtttaa accctgcaat gcggaaacat caacaatcag cgcgacgctg
    24601 ccgtcgccca ggatcgtcgc ggcggaaatc cccggtacct tgcgataatt gctttccaga
    24661 tttttgacca ccacctggtg ctgaccgatg agctgatcga ccagcagcgc gtaacggcgt
    24721 cccgcgcttt gcaggatcac aacaatgccc tgcgtggatt cggttttcgc cccgtccacg
    24781 tcaaacactt tccacaattc gaccagcggc aaatactcgc cgcgaacttc cagaacccgt
    24841 tcgccgcccg ccagcggatg aagatcctct tcacgcggtt gcagcgactc catcaccgca
    24901 tttaacggca ggataaaaac ttcccccgcc acgcgaaccg acatcccatc gaggatggcc
    24961 agcgtcagcg gcagcagaat acgaatcgtg gtgccggagc cttgttttga ctggatctca
    25021 acgtgaccgc ccatctcctg aatgttacgt ttcaccacat ccatgccaac gccgcgaccg
    25081 gagacatccg tgacctgttc cgcagttgag aatcccggcg cgaagatcaa catgcctact
    25141 tcatcgtcgg tcatgttttc attcaccgcc atcccctgcg acatggcctt cgccaggata
    25201 cgctcacggt taagccccgc gccgtcatcg gtcacttcaa tacaaatatt cccgccctga
    25261 tgttctgcag aaaggatcag attgccgaca acatttttcc ccgcctcaag gcgtttttcc
    25321 ggcatttcaa tcccgtggtc gagactgttg cgcaccaggt gcgtcagcgg gtcgataatg
    25381 cgttcgatca ggcttttatc aagttcagtg gagctcccca ccagcgtcag ctctacctgc
    25441 ttgcccagtt tgcccgctaa atcgcgtacc agacgcggga aacggctgaa gacgtactcc
    25501 ataggcatca tacgaatcga catcaccgac tcttgtaagt cgcgggcgtt acgttgtaac
    25561 tgccccatac tggtaatgag atcgccgtgg tttaccgggt ccagctcgtt agaacgctgg
    25621 gccaacattg actgggtaat cactaactcg ccgaccaggt ttatgagctg atccactttc
    25681 tctaccgcca cgcgaatgct ggtggactcg cgttcacgcg caggtttttc acgccccgca
    25741 tgatgttcat gggccgcgct tttggcggct ggcgcaacga ctgccggaga cgctaccggt
    25801 gctacctcgg ttttctcttg cgctttttca accggcgcgg tgaccacttt ttcaaaagcg
    25861 atctgatcgg cctcgatgac aaaacagagc accgcgacaa tgtcatcttc cgcgacgctg
    25921 ccatccagag ttgccgacag tgaatccgcc cccttaacga catccgtcag agtagccaga
    25981 ttgcccaact cttcttcaag cagatcgacc tcattggctt tcaaccgtga aagtacaatg
    26041 cgcagtttac tctcgtcacg aggcgattcg gtttcggcta cgctctcttc ctggatcgcc
    26101 gcacttagtg ccgcggtttc tacgaccgcc ggcgtggttt cgcctttcgc ctccagcgcc
    26161 aactggcgta gcgcattgca gatatattcg aagcttgcgg catccggctc ttcggagttt
    26221 ttataggcgt cgagctgttc ctgcataata tctttcgttt ccaaaaacag gttgataatg
    26281 tcggtattga gctgcatttc accgcgtcgg gcttcatcca gcaggttttc cattaaatgt
    26341 gtggtttcct gcagaatagt gaagccgaat gtgcccgcgc cgcctttaat ggagtgcgcc
    26401 gcgcgaaaaa tggcgttcag ttgttcagcg tccggggatt ccggcaccaa atccagcaga
    26461 tgctgctcca tatcagccaa cagctcgtca gcttcatcaa aaaatgtctg ataaaaatcg
    26521 ctaatatcca tgctcacgct atcacctcgg ttccgctttt ggcgatgtgg gtacgcttgc
    26581 cggcggggct gccgcaggct gttgtaatac acttaccggc tcattctggc tttcagcgtt
    26641 ttcatgcaaa atggcctgtt ccgcctgttt gtttaacacc agcaggctta tacggcggtt
    26701 gatggcgtca tcaggaccgc gatcgctcag ccgcatcgtg gcggccatgc caaccacccg
    26761 taatactttt ccgttatcca gcccgccagc gaccagttcg cgacgagagg cattggcgcg
    26821 atcggcggat aactcccagt tgctatagcc tttttcgccg ttcgcgtagg gaaagtcatc
    26881 ggtatggccg gccaggctaa tgcgattagg tataccgttt aacactggcg caatcgcacg
    26941 caggatatcg cgcatatacg gctcaacttc ggcgctgccg gttttaaaca tcgggcggtt
    27001 ctggctgtcg ataatctgga tgcgcaaccc ctcctgaact aaatcaattt tcagatgcgg
    27061 acgtaacgcg cgcagtttgg gatcggattc gatcagttga tccagatcgc cgcgcagttt
    27121 gtttaaccga ctctgctcca tccgtttttt cagctcgtcg atattcggct gcttttccac
    27181 ttcaccctgc tgttgggtgt aatcatcgcc gccgcctggt atcgggctct tgctattggc
    27241 aatccgattt ccccccgtta ccgcggtggc caacggcgta cgaaaatatt cggcaatctg
    27301 aattaattct ttagggctgg agatggaaat cagccacatc accagaaaaa aagccatcat
    27361 cgccgtcata aaatcggcgt aggcaatttt ccaggaaccg tgcgccccgc cgccgtgcgg
    27421 tttgtgcctg cggcgtttta cgacgacaat gggatgagcc tgatttttca tgcttcctca
    27481 gtcgtctgct gctggtttgg gtttctcact gcgcgaacgt gttcttccaa ctcaataaac
    27541 gatggacgct cactggaata aagcgtttta cgaccaaatt ccacggcaat cggcggcgca
    27601 tagccgttca gattagacag cagtgtaatt tttacgcact gcatcatctt agtggtttcg
    27661 gcgctcttct ggcgcaaaac ggtcgctaac ggtgaaatga atccataagc cagtaaaata
    27721 ccgaggaacg tacctaccat ggcatgggca atcagcgccc ccaactccgc tgccggacga
    27781 tcggctgaag ccagagcgtg aaccaccccc attaccgccg cgacgatacc aaaggcaggc
    27841 agcgaatccc ccaccatcgc cagactgttg gccgggactt ccgcctcgct ttcatgggtt
    27901 tcaatctctt catccatcaa cgcttcaatt tcgaacgtat tcatgttgcc gctgatgatc
    27961 agacgcagat aatcgacaat aaaatcaagc attaccgcat cggccagaat acgcggataa
    28021 ctggcgaaga tttcactctc tttcggattt tcaatatcgc gttcaaggga gaacatcccc
    28081 tgctggcgtg atttggccat caggcgatag agcaacgcca gcaaatccat gtacatagat
    28141 ttcgtgtatt tcgaacggcg aaataacaac gggatcgctt tcatcgtgcc tttgatggcc
    28201 ttcccgttgt tgccgacaat gaacgccccc atccccgcgc cgccaatgat gaccagttca
    28261 gcaggttgat agagtgcccc aaggtgtccg ccggtcatga cataaccgcc gaaaactgta
    28321 ccgataacca ccaagtaacc taataagata agcacgacat catccttccg ctgttgacta
    28381 tgacaggatg cgcagtcggg cgattaacgc gaaggcaagg caaaaaaaaa aagcagcggt
    28441 aatggcttac cgctgctgga gtgtttgtcc acaccgtttc ggttaaacag cctgttcgat
    28501 ctgttcatcc agcagttgtg gaataatatc ggcagcatct cgggaaagtt tacgtctttt
    28561 tactgcgcgg gatggcggct ggcataaact acacgcaaag ctgcctacgg gctgatgcgc
    28621 atgggtaata aagttcccac cgcagcagtt acagctcgac aattcaagca acccactttc
    28681 aacaaaacgc accagcgtcc atgcgcgagt cagcgccaac aacgaccctt caggcggttg
    28741 cggacactgc tcaagataaa gccgataagc tttaatcacc gcatccacac cgctgcataa
    28801 gccggtcttc agtaaaaatt gccaggcgtt gcagaacatg gaggcatgaa tattttgctc
    28861 ccaggtcata aaccagtctg tcgaaaatgg cagcatccct ttaggcggcg ggctaccgcg
    28921 taattctttg tacagcctga tgaggcgacc acggctgagc tgtgtttcgc tttccagcat
    28981 ttgtagacga gcgccaagat taatcaactc catcgccaac tggatatcgc gagcttcctg
    29041 aacaatgctt ttttcgctca ttatcatgcc cttttcttac gcgccgtatc gtccacttca
    29101 ttgagcagac gcgttgaaag catgatacct gtgtgaatct gctgtaagtc atcgacgcgc
    29161 gaatcctgag tcaaacgggt gatcgtctga tgatcgtcaa accggaaatg acaaactaac
    29221 tggttcgtct ccgccagttt gaccatctgc ggcagggtca acgcgcccag tgtgtttgcc
    29281 atctcttcgt tgataccgag gcggaacatc gcagatgctt tatcctggac gatcaaacgc
    29341 tgtgcaagga gtaaatatga caaattgatg tcataaatgt gttttagcaa ctcggatgta
    29401 tgcattgttc ccatccagaa taaccaactt tatttttgtg cgacgtagcc gcaccccgtg
    29461 atgtcgccgg gaaggtccgg taaaagaagc aaaaaggtca aatgcatagc agcgctcaga
    29521 cattatggac attgtgacgt ataacgcagc ttcccactgg gattcgcctt acacgtttac
    29581 atcaattttt acaaatgcct aagatttttc ctaattcgac gcaactctac tcgtcagttt
    29641 cgtgacatac aacggagcgg gacggcgatt ttagaaaata tgcgatgcag atcacataat
    29701 ttaacagaat acttacgata aaaccatcag tatggctttt actttgttta attaataacc
    29761 taatattcac tttttctatt ccacactgct gaataggggt acgtcaacac caaattcttt
    29821 tttgtttctc tctgtt
//
LOCUS       DAJVBX010000026        29518 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.026, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000026 DAJVBX010000000
VERSION     DAJVBX010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 29518)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29518)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29518
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.026"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..299)
                     /gene="tuf"
                     /locus_tag="OPV72_001063"
     CDS             complement(<1..299)
                     /gene="tuf"
                     /locus_tag="OPV72_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312217.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HCR9913429.1"
                     /translation="MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAA
                     RAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQM"
     gene            complement(371..2485)
                     /gene="fusA"
                     /locus_tag="OPV72_001064"
     CDS             complement(371..2485)
                     /gene="fusA"
                     /locus_tag="OPV72_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020455498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HCR9913430.1"
                     /translation="MARTTPIARYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVH
                     DGAATMDWMEQEQERGITITSAATTAFWSGMAKQYEPHRINIIDTPGHVDFTIEVERS
                     MRVLDGAVMVYCAVGGVQPQSETVWRQANKYKVPRIAFVNKMDRMGANFLKVVGQIKT
                     RLGANPVPLQLAIGAEEGFTGVVDLVKMKAINWNDADQGVTFEYEDIPADMQDLANEW
                     HQNLIESAAEASEELMEKYLGGEELTEEEIKQALRQRVLNNEIILVTCGSAFKNKGVQ
                     AMLDAVIDYLPSPVDVPAINGILDDGKDTPAERHASDDEPFSALAFKIATDPFVGNLT
                     FFRVYSGVVNSGDTVLNSVKTARERFGRIVQMHANKREEIKEVRAGDIAAAIGLKDVT
                     TGDTLCDPENPIILERMEFPEPVISIAVEPKTKADQEKMGLALGRLAKEDPSFRVWTD
                     EESNQTIIAGMGELHLDIIVDRMKREFNVEANVGKPQVAYREAIRAKVTDIEGKHAKQ
                     SGGRGQYGHVVIDMYPLEPGSNPKGYEFINDIKGGVIPGEYIPAVDKGIQEQLKSGPL
                     AGYPVVDLGVRLHFGSYHDVDSSELAFKLAASIAFKEGFKKAKPVLLEPIMKVEVETP
                     EENTGDVIGDLSRRRGMLKGQESEVTGVKIHAEVPLSEMFGYATQLRSLTKGRASYTM
                     EFLKYDDAPNNVAQAVIEARGK"
     gene            complement(2582..3052)
                     /gene="rpsG"
                     /locus_tag="OPV72_001065"
     CDS             complement(2582..3052)
                     /gene="rpsG"
                     /locus_tag="OPV72_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015873274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HCR9913431.1"
                     /translation="MPRRRVIGQRKILPDPKFGSELLAKFVNILMVDGKKSTAESIVY
                     SALETLAQRSGKSELEAFEVALENVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALAMR
                     WIVEAARKRGDKSMALRLANELSDAADNKGTAVKKREDVHRMAEANKAFAHYRW"
     gene            complement(3148..3522)
                     /gene="rpsL"
                     /locus_tag="OPV72_001066"
     CDS             complement(3148..3522)
                     /gene="rpsL"
                     /locus_tag="OPV72_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005306278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HCR9913432.1"
                     /translation="MATVNQLVRKPRARKVAKSNVPALEACPQKRGVCTRVYTTTPKK
                     PNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGAL
                     DCSGVKDRKQARSKYGVKRPKA"
     gene            complement(3648..3935)
                     /gene="tusB"
                     /locus_tag="OPV72_001067"
     CDS             complement(3648..3935)
                     /gene="tusB"
                     /locus_tag="OPV72_001067"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase complex subunit TusB"
                     /protein_id="HCR9913433.1"
                     /translation="MLHTLPHCASGVDFPALLRLLKEGDALLLLQDGVTVAIEGNRFL
                     ESLRDAPITVYALKEDIDARGLGGQISDSVVRVDYTEFVRLTVKYANQMAW"
     gene            complement(3943..4299)
                     /gene="tusC"
                     /locus_tag="OPV72_001068"
     CDS             complement(3943..4299)
                     /gene="tusC"
                     /locus_tag="OPV72_001068"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase complex subunit TusC"
                     /protein_id="HCR9913434.1"
                     /translation="MKRIAFVFSTAPHGSASGREGLDALLATSALTEALGVFFISDGV
                     FQLLPGQKPDAVLARDYIATFKLFDLYDIDQCWICAASLRERGLENVNFVVNATPLEP
                     VALRRELGNYDVILRF"
     gene            complement(4299..4685)
                     /gene="tusD"
                     /locus_tag="OPV72_001069"
     CDS             complement(4299..4685)
                     /gene="tusD"
                     /locus_tag="OPV72_001069"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase complex subunit TusD"
                     /protein_id="HCR9913435.1"
                     /translation="MRYAIMVTGPAYGTQQASSALQFAHALLNEGHELASVFFYREGV
                     YNANLLTSPASDEYDLVRVWQKLNTQHGVALNICVAAALRRGIIDETEAGRLELPSAN
                     LQPGFTLSGLGALAEASLTCDRVVQF"
     gene            complement(4685..5407)
                     /locus_tag="OPV72_001070"
     CDS             complement(4685..5407)
                     /locus_tag="OPV72_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCR9913436.1"
                     /translation="MSRSLLTNETSELDLLDQRPFEQTDFDILKSYEAVVDGLAMLIG
                     SHCEIVLHSLQDLKCSAIRIANGEHTGRKIGSPITDLALRMLHDMTGADSSVSKCYFT
                     RAKSGVLMKSLTIAIRNREQRVIGLLCINMNLDVPFSQIMNTFIPPETPEVGSAVNFA
                     SSVEDLVTQTLEFTIEEVNADRNVSNNAKNRQIVLNLYEKGIFDIKDAINQVADRLNI
                     SKHTVYLYIRQFKSGDFQGQDK"
     gene            complement(5684..6502)
                     /gene="fkpA"
                     /locus_tag="OPV72_001071"
     CDS             complement(5684..6502)
                     /gene="fkpA"
                     /locus_tag="OPV72_001071"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HCR9913437.1"
                     /translation="MKSLFKATLLATTMAVAMHVPITFAADAAKPAATADSKAAFKND
                     DQKAAYALGASLGRYMENSLKEQEKLGIKLDKDQLIAGVQDAFADKSKLSDQEIEQTL
                     QTFEARVKSAAQAKMEKDAADNEAKGKTFRDAFAKEKGVKTSSTGLLYKVEKEGTGEA
                     PKDSDTVVVNYKGTLIDGKEFDNSYTRGEPLSFRLDGVIPGWTEGLKNIKKSGKIKLV
                     IPPALAYGKTGVPGIPANSTLVFDVELLDIKPAPKADAKPADAADAKAADAAKK"
     gene            6722..6940
                     /locus_tag="OPV72_001072"
     CDS             6722..6940
                     /locus_tag="OPV72_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein SlyX"
                     /protein_id="HCR9913438.1"
                     /translation="MQDITMEARLAELESRLAFQEITIEELNLTVTAHEMEMAKLRNH
                     LRLLTEKLKASQPSNIASQAEETPPPHY"
     gene            complement(7127..7717)
                     /gene="slyD"
                     /locus_tag="OPV72_001073"
     CDS             complement(7127..7717)
                     /gene="slyD"
                     /locus_tag="OPV72_001073"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCR9913439.1"
                     /translation="MKVAKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLISG
                     LETALEGHEVGDKFDVAVGANDAYGQYDENLVQRVPKDVFMGVDELQVGMRFLAETDQ
                     GPVPVEITEVEDDHVVVDGNHMLAGQNLKFNVEVVAIREATEEELAHGHVHGAHDHHH
                     DHGEDGCCSGHGHDHGHEHGGEGCCGGGGKGSCGCH"
     gene            complement(7812..8012)
                     /locus_tag="OPV72_001074"
     CDS             complement(7812..8012)
                     /locus_tag="OPV72_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YheV family putative metal-binding protein"
                     /protein_id="HCR9913440.1"
                     /translation="MAIRKRFIAGAKCPACQAQDTMAMWRENNVDIVECVKCGHQMRE
                     ADKDVREHVRKEEQVIGIFHPD"
     gene            complement(8022..9827)
                     /gene="kefB"
                     /locus_tag="OPV72_001075"
     CDS             complement(8022..9827)
                     /gene="kefB"
                     /locus_tag="OPV72_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     protein KefB"
                     /protein_id="HCR9913441.1"
                     /translation="MEGADLLTAGVLFLFAAVAAVPLAARLGIGAVLGYLLAGIAIGP
                     WGLGFISDVDEILHFSELGVVFLMFIIGLELNPSRLWQLRRSIFGVGAAQVLLSAAVL
                     AGLLMLADFLWQAAVVGGIGLAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAV
                     IPALALVPLLAGSADEHFDWFKVAMKVLAFAVMLIGGRYLLRPVFRFIAASGVREVFT
                     AATLLLVLSAALFMDALGLSMALGTFIAGVLLAESEYRHELENAIDPFKGLLLGLFFI
                     SVGMSLNLGVLYTHLLWVAASVVILVVIKMLTLYLLARLYGIRSSERMQFASVLSQGG
                     EFAFVLFSTASSQRLFQGDQMALLLVTVTLSMMTTPLLMKGIDKWLSRRLNGPEENDE
                     KPWVEDDKPQVVVVGFGRFGQVIARLLMANKMRITVLERDIGAVNLMRKYGYKVYYGD
                     ATQVELLRSAGAEAAESIVITCNEPEDTMKLVALCQQHFPHLHILARARGRVEAHELL
                     QAGVTQFSRETFSSALELGRKTLVSLGMHPHQAQRAQLHFRRLDMRMLRELIPEHSDM
                     VQISRAREARRELEEIFQREMQQERRQLDGWDEFE"
     gene            complement(9827..10378)
                     /gene="kefG"
                     /locus_tag="OPV72_001076"
     CDS             complement(9827..10378)
                     /gene="kefG"
                     /locus_tag="OPV72_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     ancillary protein KefG"
                     /protein_id="HCR9913442.1"
                     /translation="MSQPAKVLLLYAHPESQDSVANRVLLKPAIQHNNVTVHDLYARY
                     PDFFIDTPYEQALLREHDVIVFQHPLYTYSCPALLKEWLDRVLSRGFASGPGGNQLVG
                     KYWRSVITTGEPESAYRYDALNRYPMSDVLRPFELTAAMCRMHWMPPIIVYWARRQSP
                     QTLASHAKAYGEWLANPVSAGGY"
     gene            10644..12551
                     /locus_tag="OPV72_001077"
     CDS             10644..12551
                     /locus_tag="OPV72_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR9913443.1"
                     /translation="MIVFSSLQIRRGVRVLLDNASATINPGQKVGLVGKNGCGKSTLL
                     ALLKNEISADAGSFTLPGTWQLAWVNQETPALPQPAIEYVIDGDREYRHLEAQLNDAN
                     ERNDGHAIASIHGKLDAIDAWTVRSRAASLLHGLGFSNDQLERPVSDFSGGWRMRLNL
                     AQALICRSDLLLLDEPTNHLDLDAVIWLEKWLKSYPGTLILISHDRDFLDPIVDKIIH
                     IEQQTLFEYTGNYSAFEVQRATRLAQQQAMYESQQERVAHLQSYIDRFRAKATKAKQA
                     QSRIKMLERMELIAPAHVDNPFHFSFRAPESLPNPLLKMEKVSAGYGDRIILESIKLN
                     LVPGSRIGLLGRNGAGKSTLIKLLAGELEPLHGEIGLAKGIKLGYFAQHQLEFLRADE
                     SPLQHMARLAPQELEQKLRDYLGGFGFQGDKVTEETQRFSGGEKARLVLALIVWQRPN
                     LLLLDEPTNHLDLDMRQALTEALIDFEGALVVVSHDRHLIRSTTDDLYLVHDKKVEPF
                     DGDLEDYQQWLSDVQKQENQADDAPKENNANSAQSRKDQKRREAELRTLTQPLRKEIT
                     RLEKEMEKLNAQLAQAEEKLGDSSLYDPSRKAEMTECLQLQASAKSGLEECEMAWLEA
                     QEQLEQMMQND"
     gene            12696..12917
                     /locus_tag="OPV72_001078"
     CDS             12696..12917
                     /locus_tag="OPV72_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001054026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCR9913444.1"
                     /translation="MNLSITDDITFRKLTIFMMLVEKGNIARTAETLHTLEENVRCPL
                     FVHKGLFGTRPDIKVTVAVGSTGTEACVM"
     gene            complement(12919..13230)
                     /locus_tag="OPV72_001079"
     CDS             complement(12919..13230)
                     /locus_tag="OPV72_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monooxygenase"
                     /protein_id="HCR9913445.1"
                     /translation="MSKTLLQIHFNFSGPFGEEMTQQLVGLAESINEEPGFIWKIWTE
                     SEKNQQAGGIYLFESEETAQAYIKKHTARLKNLGVDEVTFTLFGVNDALTKINHGNLC
                     R"
     gene            13428..14415
                     /locus_tag="OPV72_001080"
                     /pseudo
     CDS             13428..14415
                     /locus_tag="OPV72_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462365.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
     gene            14412..14630
                     /locus_tag="OPV72_001081"
     CDS             14412..14630
                     /locus_tag="OPV72_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462366.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YheU family protein"
                     /protein_id="HCR9913446.1"
                     /translation="MIIPWQGLAPDTLDNLIESFVLREGTDYGEHERSLEQKVADVKR
                     QLQSGEAVLVWSELHETVNIMPKKQFRE"
     gene            14682..15551
                     /locus_tag="OPV72_001082"
     CDS             14682..15551
                     /locus_tag="OPV72_001082"
                     /EC_number="2.7.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HCR9913447.1"
                     /translation="MSAKHPVIAVTGSSGAGTTTTSLAFRKIFAQLNLHAAEVEGDSF
                     HRYTRPEMDMAIRKARDAGRHISYFGPEANDFSLLEHTFIEYGQTGKGQSRKYLHTYD
                     EAVPWNQVPGTFTPWQPLPEPTDVLFYEGLHGGVVTPQHDVARHVDLLVGVVPIVNLE
                     WIQKLIRDTSERGHSREAVMDSVVRSMDDYINYITPQFSRTHINFQRVPTVDTSNPFA
                     AKGIPSLDESFVVIHFRNLEGIDFPWLLAMLQGSFISHINTLVVPGGKMGLAMELIML
                     PLVQRLMEGKKIE"
     gene            complement(15647..16051)
                     /locus_tag="OPV72_001083"
     CDS             complement(15647..16051)
                     /locus_tag="OPV72_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HCR9913448.1"
                     /translation="MQARVKWVEGLTFLGESSSGHQILMDGNSGDKAPSPMEMVLMAA
                     GGCSAIDVVSILQKGRQNVTNCEVKLTSERREDAPRLFTHINLHFIVTGGDLKEAAVA
                     RAVDLSAEKYCSVALMLEKAVNITHSYEVIAA"
     gene            16359..16991
                     /gene="crp"
                     /locus_tag="OPV72_001084"
     CDS             16359..16991
                     /gene="crp"
                     /locus_tag="OPV72_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016506431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cAMP-activated global transcriptional regulator
                     CRP"
                     /protein_id="HCR9913449.1"
                     /translation="MVLGKPQTDPALEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIV
                     KGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEGQERSAWVRAKTACEVAEISYKK
                     FRQLIQVNPDILMRLSSQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
                     PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR"
     gene            17040..19127
                     /locus_tag="OPV72_001085"
                     /pseudo
     CDS             17040..19127
                     /locus_tag="OPV72_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462370.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
     gene            complement(19170..20387)
                     /locus_tag="OPV72_001086"
     CDS             complement(19170..20387)
                     /locus_tag="OPV72_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate aminotransferase family protein"
                     /protein_id="HCR9913450.1"
                     /translation="MATEQTAITRATFDEVILPVYAPADFIPVKGKGSRVWDQQGKEY
                     IDFAGGIAVTALGHCHPALVEALKSQGETLWHTSNVFTNEPALCLGRKLIDATFAERV
                     LFMNSGTEANETAFKLARHYACVRHSPFKTKIIAFQNAFHGRSLFTVSVGGQPKYSDG
                     FGPKPADIIHVPFNDLHAVKAVMDDHTCAVVVEPIQGEGGVQAATPEFLKGLRDLCDK
                     HQALLVFDEVQCGMGRTGDLFAYMHYGVTPDILTSAKALGGGFPVSAMLTTQEIASAF
                     HVGSHGSTYGGNPLACAVAGAAFDIINTPEVLQGIHTKRQQFVQHLQAIDEQFDIFSD
                     IRGMGLLIGAELKPKYKGRARDFLYAGAEAGVMVLNAGADVMRFAPSLVVEEADINEG
                     MQRFAQAVGKVVA"
     gene            complement(20473..21036)
                     /gene="pabA"
                     /locus_tag="OPV72_001087"
     CDS             complement(20473..21036)
                     /gene="pabA"
                     /locus_tag="OPV72_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component 2"
                     /protein_id="HCR9913451.1"
                     /translation="MILLIDNYDSFTWNLYQYFCELGAEVQVRRNDALTLAHIDALNP
                     QKIVISPGPCTPNDAGISLAVIRHYAGRIPMLGVCLGHQAMAQAFGASVVRAAKVMHG
                     KTSPVTHNGQGVFRGLPSPLTVTRYHSLIVDPATLPECFEITAWSETQEIMGIRHREW
                     DLEGVQFHPESILSEQGHALLENFLRR"
     gene            complement(21068..21670)
                     /locus_tag="OPV72_001088"
     CDS             complement(21068..21670)
                     /locus_tag="OPV72_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative adenosine monophosphate-protein
                     transferase Fic"
                     /protein_id="HCR9913452.1"
                     /translation="MSDKFGEGRDPYLYPGLNVMRNRLGIHQAQRLAQAAYEMTALRA
                     ATIELGPLVRGLPHLCAIHRQLYQDIFDWAGQLREVDIYQGDTRFCHFAYIEKEGNAL
                     MQDLEEEGYLVGLTHEKFVERLAHYYCEINVLHPFRLGSGLAQRIFFEQLALHAGYAL
                     SWQGIAVETWNQANQSGAMGDLSALRAIFQKAISEARETE"
     gene            complement(21660..21827)
                     /locus_tag="OPV72_001089"
     CDS             complement(21660..21827)
                     /locus_tag="OPV72_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfG family protein"
                     /protein_id="HCR9913453.1"
                     /translation="MKKLTDKQKSRFWEQRRNVNFQQSRRLEGIEIPLVTLTADEALA
                     RLDELRRHYER"
     gene            complement(21936..22508)
                     /gene="ppiA"
                     /locus_tag="OPV72_001090"
                     /gene_synonym="rotA"
     CDS             complement(21936..22508)
                     /gene="ppiA"
                     /locus_tag="OPV72_001090"
                     /gene_synonym="rotA"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase A"
                     /protein_id="HCR9913454.1"
                     /translation="MLKSTLAAVAAVFALSALSPVALAAKGDPHVLLTTSAGNIELEL
                     NSQKAPVSVKNFVDYVNSGFYNNTTFHRVIPGFMIQGGGFNEQMQQKKPNPPIKNEAD
                     NGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYAVFGKVVKGMDVAD
                     KISQVPTHDVGPYQNVPTKPVVILSAKVLP"
     gene            22785..23966
                     /gene="tsgA"
                     /locus_tag="OPV72_001091"
     CDS             22785..23966
                     /gene="tsgA"
                     /locus_tag="OPV72_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter TsgA"
                     /protein_id="HCR9913455.1"
                     /translation="MTNSNRIKLTWISFLSYALTGALVIVTGMVMGNIADYFQLPVSS
                     MSNTFTFLNAGILISIFLNAWLMEIVPLKTQLRFGFILMVLAVAGLMFSHSLALFSAA
                     MFVLGLVSGITMSIGTFLITQLYEGRQRGSRLLFTDSFFSMAGMIFPMVAAFLLARSI
                     EWYWVYACIGLVYLAIFILTFGCEFPALGKHAQHSQAPVVKEKWGIGVLFLAVAALCY
                     ILGQLGFISWVPEYAKGLGMSLNDAGALVSDFWMSYMFGMWAFSFILRFFDLQRILTV
                     LAGMAAILMYLFITGTQAHMPWFILTLGFFSSAIYTSIITLGSQQTKVASPKLVNFIL
                     TCGTIGTMLTFVVTGPIVAHSGPQAALLTANGLYAVVFVMCFALGFVSRHRQHSSPAA
                     H"
     gene            24283..26826
                     /gene="nirB"
                     /locus_tag="OPV72_001092"
     CDS             24283..26826
                     /gene="nirB"
                     /locus_tag="OPV72_001092"
                     /EC_number="1.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-nitrite reductase large subunit"
                     /protein_id="HCR9913456.1"
                     /translation="MSKVRLAIIGNGMVGHRFIEDLLDKSDASLFDITVFCEEPRKAY
                     DRVHLSSYFSHHTAEELSLVREGFYEKHGVKVLVGERAITINRQEKVIHSSAGRTVYY
                     DKLIMATGSYPWIPPIKGSETQDCFVYRTIEDLNAIEACARRSKRGAVVGGGLLGLEA
                     AGALKNLGVETHVIEFAPMLMAEQLDQMGGEQLRRKIESMGVRVHTSKNTQEIVQQGN
                     EARKTMRFADGSELEVDFIVFSTGIRPRDKLATQCGLAVAQRGGIVINDTCQTSDPDI
                     YAIGECASWNNRVYGLVAPGYKMAQVAVDHILGSENAFEGADLSAKLKLLGVDVGGIG
                     DAHGRTPGARSYVYLDESKEVYKRLIVSEDNKTLLGAVLVGDTSDYGNLLQLVLNAIE
                     LPENPDSLILPSHASSGKPAIGVDKLPDSAQICSCFDVTKGDLIAAINKGCHTVAALK
                     AETKAGTGCGGCIPLVTQVLNAELAKQGIEVNNNLCEHFAYSRQELFHLIRVEGIKTF
                     EELLTKHGKGYGCEVCKPTVGSLLASCWNEYILKPQHTPLQDTNDNFLANIQKDGTYS
                     VIPRSAGGEITPEGLVAVGRIAREFNLYTKITGSQRIGLFGAQKDDLPEIWRQLIEAG
                     FETGHAYAKALRMAKTCVGSTWCRYGVGDSVGFGVELENRYKGIRTPHKMKFGVSGCT
                     RECAEAQGKDVGIIATEKGWNLYVCGNGGMKPRHADLLAADLDRDTLIKYLDRFMMFY
                     IRTADKLTRTAPWLDNLEGGIEYLKSVIIDDKLGLNEHLEEEMARLRAAVVCEWTETV
                     NTPAAQVRFKHFINSDKRDPNVQVVPEREQHRPATPYERIPVTLVEENA"
     gene            26823..27149
                     /gene="nirD"
                     /locus_tag="OPV72_001093"
     CDS             26823..27149
                     /gene="nirD"
                     /locus_tag="OPV72_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite reductase small subunit NirD"
                     /protein_id="HCR9913457.1"
                     /translation="MSQWQNICKIDDILPGTGVCALSGGEQVAIFRPYHSDQVFAISN
                     IDPFFEASVLSRGLIAEHQGELWVASPLKKQRFRLSDGLCMEDEQFSVKHYDARVKDG
                     VVQLRG"
     gene            27331..28140
                     /gene="nirC"
                     /locus_tag="OPV72_001094"
     CDS             27331..28140
                     /gene="nirC"
                     /locus_tag="OPV72_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite transporter NirC"
                     /protein_id="HCR9913458.1"
                     /translation="MFTDTINKCAANAARIARLSANNPLGFWVSSAMAGAYVGLGIIL
                     IFTLGNLLDPSVRPLVMGATFGIALTLVIIAGSELFTGHTMFLTLGVKAGTISHGQMW
                     AILPQTWLGNLVGSVFVALLYSWGGGSLLPVDTSIVHSVALAKTTAPATVLFFKGALC
                     NWLVCLAIWMAIRTEGTAKFLAIWWCLLAFIASGYEHSVANMTLFALSWFGHHSDAYT
                     LSGIGHNLLWVTLGNTLSGVVFMGLGYWYATPKSERPVPQKTNQIKATANH"
     gene            28152..>29518
                     /gene="cobA"
                     /locus_tag="OPV72_001095"
     CDS             28152..>29518
                     /gene="cobA"
                     /locus_tag="OPV72_001095"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HCR9913459.1"
                     /translation="MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLEAGARLTVNALT
                     FIPQFTVWVNEGMLTLVEGPFDETLLDSCWLAIAATDDDTVNQRVSEAAESRRIFCNV
                     VDAPKAASFIMPSIIDRSPLMVAVSSGGTSPVLARLLREKLESLLPQHLGQVARYAGQ
                     LRARVKKQFATMGERRRFWEKFFVNDRLAQSLANADEKAVNATTEHLFSEPLDHRGEV
                     VLVGAGPGDAGLLTLKGLQQIQQADIVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHC
                     VPQEEINQILLREAQKGKRVVRLKGGDPFIFGRGGEELETLCHAGIPFSVVPGITAAS
                     GCSAYSGIPLTHRDYAQSVRLVTGHLKTGGELDWENLAAEKQTLVFYMGLNQAATIQE
                     KLIAFGMEANMPVALVENGTSVKQRVVHGVLTQLGELAQQVESPALIIVGRVVALRDK
                     LNWFS"
BASE COUNT         6931 a         8133 c         7639 g         6815 t
ORIGIN      
        1 tccatctgcg cagcaccggt gatcatgttt tttacatagt cggcgtgccc cgggcagtct
       61 acgtgtgcgt agtggcgggt cggggtatcg tattcaacgt gagaagtgtt gatggtgata
      121 ccacgcgctt tttcttccgg agcgttatcg atctggtcga atgcacgagc agcaccgccg
      181 taggttttag ccagtacggt ggtgattgca gcggtcaggg tagttttacc gtggtcaacg
      241 tggccgatgg tgccgacgtt aacgtgcggt tttgtacgtt caaatttttc tttagacacg
      301 gctatattcc ttactatagc gctctcccct tcaggagaga gcacgggatt ttggttttta
      361 accctgcggc ttatttacca cgggcttcga ttacggcctg agcaacgttg ttcggcgcat
      421 catcatactt caggaattcc atagtgtacg atgcgcgacc tttggtcaga gaacgcagct
      481 gagttgcata tccgaacatt tcagacagcg gtacttcagc gtggatctta acgcctgtaa
      541 cttcagattc ctgacctttg agcataccac gacggcggct aaggtcgccg ataacgtcac
      601 cggtattctc ttcaggtgtt tctacttcaa ccttcatgat cggctcaagc agaactggtt
      661 ttgctttctt aaagccttct ttaaaggcga tagacgcagc cagtttaaac gccagctcag
      721 aggagtcaac gtcatggtaa gaaccgaagt gcagacgcac accgagatca actaccggat
      781 aacccgccag cgggccagat ttcagctgct cctggatgcc tttatcaacg gccgggatgt
      841 actcgccagg aattacacca cctttgatgt cgttgatgaa ctcgtaacct ttcgggttag
      901 agcccggctc cagcgggtac atgtcgataa caacatgacc atactgaccg cgaccaccag
      961 actgtttcgc gtgtttacct tcgatgtcgg taactttcgc gcgaatcgct tcgcggtaag
     1021 caacctgagg tttacccacg ttcgcttcaa cgttgaattc acgcttcata cggtcaacga
     1081 tgatatctag gtgaagttca cccataccag cgatgatggt ctggttagat tcttcatcag
     1141 tccatacgcg gaacgacggg tcttctttcg ccagacggcc cagagccaga cccatttttt
     1201 cctggtcagc tttggttttc ggttctaccg cgatggagat taccggctca gggaattcca
     1261 tacgttccag aatgatcggg ttttccggat cacacagggt gtcaccggta gtcacgtctt
     1321 tcaggccgat agcagccgcg atgtcgcccg cgcgaacttc tttgatctct tcacgtttgt
     1381 tagcgtgcat ctgaacgata cgaccgaaac gctcacgtgc ggttttcacg gagttcagta
     1441 cggtatcacc agagttaacc acaccggagt acacacggaa gaaggtcagg ttacccacaa
     1501 acgggtcggt agcgattttg aacgccagcg cagagaacgg ctcgtcgtcg cttgcgtgac
     1561 gctcagccgg agtatcttta ccgtcgtcca gaataccgtt gatcgcaggt acgtctaccg
     1621 gggatggcag gtaatcaatt accgcatcca gcatcgcctg aacacctttg ttcttaaatg
     1681 cagaaccaca ggttaccagg atgatttcgt tgttcagaac gcgctgacgc agagcttgtt
     1741 tgatctcttc ttcagtcagt tcttcaccac ccaggtattt ttccatcagc tcttcagaag
     1801 cttctgcggc ggactcgatc aggttctggt gccattcgtt agccaggtcc tgcatgtcag
     1861 ccgggatatc ttcgtattcg aaggtaacgc cctggtcggc atcgttccag ttgatggctt
     1921 tcattttcac caggtcaaca acgccggtga aaccttcttc agcaccaatt gccagctgca
     1981 gcggaaccgg gttcgcgccc agacgggttt tgatctgacc aacaactttc aggaagttcg
     2041 cgcccatgcg gtccattttg ttaacgaacg caatgcgcgg aactttgtat ttgtttgcct
     2101 gacgccatac ggtttcagac tgcggctgaa caccaccaac tgcgcagtaa accattaccg
     2161 caccatcgag aacacgcatg gaacgttcta cttcgatagt gaagtcaacg tgccccgggg
     2221 tgtcgatgat gttgatgcga tgcggttcat actgcttagc cataccagac cagaatgcag
     2281 tagtcgctgc ggaggtgata gtaataccac gctcctgctc ctgctccatc cagtccatgg
     2341 tagctgcgcc gtcatgaact tcaccgattt tgtggtttac accggtgtag aacagaatac
     2401 gttcggtagt agtggtttta ccggcgtcga tgtgcgcact gataccgata ttacggtagc
     2461 gtgcgatggg tgttgtacga gccatttgat tcctcgttga tatctttagg cgttcagtta
     2521 agttatccaa aacgggcgac ttacctgaag cgcccgcctg gtgactatga ctccgaaggg
     2581 attaccaacg gtagtgtgcg aacgccttgt tggcttctgc catacggtga acgtcttcac
     2641 gtttcttaac tgcagtacct ttgttgtctg cagcgtcaga aagttcgttc gccaggcgca
     2701 gagccatgga tttatcaccg cgtttacgag cagcttctac gatccaacgc attgccagag
     2761 cattacgacg gaccggacgg acttcaactg gtacctgata agtagaacca cctacacggc
     2821 gggatttaac ttctacagtc gggcgaacgt tttcgagagc gacttcgaaa gcttccagtt
     2881 cagatttacc agaacgctga gccagggtct ccagcgcgct gtatacgatt gattctgcag
     2941 tagatttttt accatctacc atcaggatat tgacaaattt agccagcagt tctgatccga
     3001 acttcggatc cggcagaatt ttacgctgac caatgacgcg acgacgtggc atggaaatac
     3061 tccgttgtta attcaggatt gtccaaaact ctacgagttt agtttgacat taatttaaaa
     3121 cgtttggcct tacttaacgg agaaccatta agccttagga cgcttcacgc cgtacttaga
     3181 acgagcttgc ttacggtctt taacgccgga gcagtcaagc gcgccacgaa cggtgtggta
     3241 acgaacaccc gggaggtctt taacacgacc gccacggatc aggatcacgg agtgctcctg
     3301 caggttgtga ccttcaccac cgatgtagga agtcacttca aaaccgttag tcagacgaac
     3361 acggcaaact ttacgcagtg cggagttcgg ttttttagga gtggtagtat atacacgagt
     3421 acatacgcca cgtttttgcg ggcatgcttc cagcgcaggc acgttgcttt tcgcaacttt
     3481 gcgagcacgt ggtttgcgta ccagctggtt aactgttgcc attaaatagc tcctggtttt
     3541 agcttttgct tcgtaaacac gtaataaaac gccctcacac aatatgagga cgccgaattt
     3601 tagggcggtg tcgaaaaggt gtcaagaaat atacaacgat cccgccatca ccaggccatc
     3661 tggttggcat acttaaccgt gagtctgaca aactcagtat agtcaaccct gacgacactg
     3721 tctgaaattt gaccacccag gccgcgagcg tcaatgtctt ctttcaaggc atagaccgtt
     3781 atgggggcat cgcgcagact ttcaaggaag cggttacctt caatcgcgac ggtaacgcca
     3841 tcctggagca gcaaaagcgc atcgccctct tttagcaggc gcagcaaagc gggaaaatca
     3901 acgcccgaag cgcaatgagg taaggtatgc agcataaacg cctcagaatc tcaggatgac
     3961 atcatagttg ccaagctcgc ggcgtaacgc cacgggttcc agcggcgtgg cgtttaccac
     4021 aaaattaacg ttttccagac cacgctcgcg cagcgatgcc gcgcagatcc agcattgatc
     4081 aatatcgtac aaatcaaaga gcttgaaagt agcaatatag tcacgcgcca gcacagcgtc
     4141 tggtttttgc cccggtaata actgaaagac gccgtcgctg ataaaaaaga cgcccagcgc
     4201 ttccgttagc gctgacgtcg ccagcagcgc atccagtcct tcacggcctg aggcgctacc
     4261 gtgcggcgcg gtggaaaaga caaatgcaat acgtttcatt aaaactgcac cacccgatcg
     4321 caggtgagag aagcctccgc cagcgcgccc agtccgctta gcgtaaagcc cggctgaaga
     4381 ttggcggacg gcaactccag tctgccggct tcagtttcat caataatacc gcgacgaagc
     4441 gccgccgcga cacagatgtt cagcgctacg ccatgctgcg tattcaattt ctgccagacg
     4501 cgtaccagat catattcatc gctcgccggc gaggtcagga gattggcgtt atagacacct
     4561 tcccgataga aaaagacgct ggctaactca tgcccctcat tgagcagcgc gtgggcgaac
     4621 tgcaatgcgc tgctggcctg ctgggtgcca tatgcaggcc cggtgaccat aatggcataa
     4681 cgcattattt atcctgcccc tgaaaatcgc cgcttttgaa ctggcgaata tagaggtaaa
     4741 ccgtgtgttt tgagatattc agacgatcgg ctacctggtt aatggcgtct ttaatatcga
     4801 aaatgccttt ttcgtacaag ttaaggacga tctgacgatt tttcgcattg ttagagacat
     4861 tacgatcggc attcacttct tcgatcgtga actccagcgt ctgggtgact aaatcttcga
     4921 ctgaggaggc aaaattaacc gctgagccga cttccggcgt ttccggcgga ataaaggtat
     4981 tcataatctg tgaaaatggc acatcaagat tcatgttgat gcacagtaga ccaatgacgc
     5041 gctgctcgcg gttgcgaatg gcaatcgtca acgacttcat caagacaccg cttttcgcgc
     5101 gcgtaaaata gcatttcgac acgctactgt ccgcccctgt catgtcgtgc aacatgcgca
     5161 acgccaggtc ggtaatcggc gagccaattt tacggcccgt atgttcgcca ttggcaatac
     5221 gaatggctga acattttaga tcctgcaaag agtgcaatac gatttcacaa tgggaaccta
     5281 taagcatcgc taacccgtcc actaccgctt cgtaggattt cagaatatcg aagtcggttt
     5341 gctcgaaggg acgctgatcc agcaaatcaa gttcactggt ttcgttggtt aaaagcgacc
     5401 tggacatgaa aaaaaacact ccttttcagg agcctgtcgt tatgttttca gggcaggctc
     5461 attatttacg cggatgatta aattaataca gtgagggttc atctttccag tactaatttg
     5521 ctcgtctatt tcagactacg tgtgcgttgg cggtcattca gcctacggtc tcgcccttaa
     5581 cgaccagcgc aagcgccgtt atccgcaaat caaattatgg tgagtaatat atccggcctg
     5641 aataaaaaaa accgccgcta ttacaagcgg cggctctcag tttttatttt ttagcagcat
     5701 ctgcggcttt agcgtcagcc gcatcggcag gtttagcatc cgctttcggc gctggtttga
     5761 tatccagcag ctctacgtcg aataccaggg tggagttcgc agggataccc ggaacgcccg
     5821 ttttaccgta ggccagcgcc ggtgggataa ccagcttgat cttgccgctt ttcttaatat
     5881 ttttcaggcc ttcagtccag ccagggataa cgccgtccag acggaaggag agcggttcgc
     5941 cgcgcgtgta agagttatca aactctttac cgtcgatcag cgtacctttg tagttcacca
     6001 caacggtatc gctatctttc ggcgcctcgc ctgtgccttc tttctctact ttgtaaagca
     6061 gaccggtaga ggaggttttc acgcctttct ctttagcaaa agcgtcacgg aacgttttac
     6121 cttttgcttc gttatcggca gcgtcttttt ccatcttcgc ctgagcagcg ctcttcacac
     6181 gtgcttcaaa cgtctgcagc gtttgctcaa tttcctgatc ggacagtttg ctcttatcgg
     6241 caaaggcatc ctgaacgccg gcaatcaact gatctttatc cagtttgatg cccaactttt
     6301 cctgctcttt aagcgaattt tccatgtaac gacccagcga ggcgcccagc gcataagccg
     6361 ctttttgatc gtcgttttta aatgctgctt tgctatcagc ggtagctgcc ggtttcgccg
     6421 catcagcagc aaaagtgatc ggtacgtgca tagcaacggc catcgtcgtt gccagcagcg
     6481 tggctttaaa cagtgatttc atccatatct ccagggccgg ggcatctcgc cccatgttaa
     6541 cttacgtaag aagcgtacta taaatcgttg cagaacaaat caacatacga acacgcccta
     6601 ttatcacttc ttttcagact ctttttgttt aaattagttt cgtagggcgc gtaatggttg
     6661 ctgtgaaagc cggtaaagtt aagtagaatc cgccgacgga gacaacataa agaggtacat
     6721 catgcaggat atcacgatgg aagctcgtct ggctgaactg gaaagccgtc tggcgttcca
     6781 ggagattacc atagaagaac taaacctgac ggtaaccgca catgaaatgg agatggcgaa
     6841 gctgcgcaat catctgcgtt tgctcacgga aaagttaaaa gccagtcagc cgtcaaatat
     6901 cgcctctcag gcagaagaaa cgccgccgcc gcattattga gacgaaaaaa agcggggata
     6961 cccgcttttt ttgtgcccga tgatttatcg aaccaatgat aataacctaa ggatttcgag
     7021 tcacagcaaa gcggcaagct tgaaaattcc ccgggaacat agataactat gtgaccgggg
     7081 tttgaaagcg tagccaacac cgcggtggct tgaaagacga cggggattaa tggcagccgc
     7141 agctgccttt accaccaccg ccgcagcagc cttcgccgcc gtgctcgtga ccatggtcat
     7201 gaccatgacc gctacagcag ccgtcttcac cgtgatcgtg gtggtgatcg tgcgcgccgt
     7261 gaacatgacc gtgagccagt tcttcttcag tcgcttcacg aatcgcaaca acttcgacgt
     7321 taaatttcag attctggccc gccagcatgt ggttaccatc aaccacaacg tgatcgtctt
     7381 ccacttcggt aatctctacc ggtaccgggc cctggtcggt ttccgccagg aaacgcatcc
     7441 ctacctgcag ttcatcaacg cccataaaga cgtctttagg cacacgctgc accagatttt
     7501 cgtcatactg gccgtaagcg tcgttcgcgc caacagcgac atcaaatttg tcgccaactt
     7561 catggccttc cagcgcggtt tccagaccag agatcaggga gccgtgaccg tgcaggtaat
     7621 ccagcggcgc actcaccgga gactcatcaa ccaacacacc gtcttctgta cgtacctgat
     7681 aggccaggct gaccaccagg tcttttgcta ctttcatgat atctcctgag catgggaaga
     7741 atagtggcgc agattgtagc ggaattctgc agccgtgtac cccttagctt aaaaaaacct
     7801 gcggcatatc gctagtccgg atgaaaaatc ccgatcactt gctcttcttt gcgaacatgc
     7861 tcgcgaacgt ctttatccgc ttcccgcatt tgatgcccgc acttaacgca ttcaacaata
     7921 tcgacattat tttcacgcca catcgccatt gtatcctgcg cctgacaggc cggacatttc
     7981 gcgcctgcaa taaaacgttt acggattgcc attgttcacc tctactcaaa ttcatcccag
     8041 ccatccaact ggcgccgttc ctgttgcatt tcgcgctgaa aaatctcctc cagctcgcgt
     8101 cgggcctctc tggcgcgcga aatctgtacc atgtcgctat gctccgggat cagctcccgc
     8161 aacattcgca tatccagccg acgaaaatgc aactgcgcgc gttgcgcctg atgcggatgc
     8221 atacctaacg acaccagagt tttacgtccc agttccagcg cgctggaaaa cgtttcacgg
     8281 gaaaactgcg tgacgccagc ctgtaataac tcatgggcct ccacacgtcc acgcgctcgc
     8341 gcaagaatat gcagatgagg aaaatgctgc tgacacagcg ccaccagctt catcgtgtct
     8401 tccggttcat tacacgtgat gactatcgac tccgccgcct ccgcgcccgc agaacgcagc
     8461 agctcgactt gtgtagcgtc gccgtaatac actttataac catatttgcg catcagatta
     8521 acggcgccga tatcgcgttc cagcacggtg atacgcatct tattcgccat caataagcga
     8581 gcgatcacct gaccaaaacg gccaaagccg acgacaacca cctggggctt atcatcctca
     8641 acccacggct tttcatcatt ctcttccggg ccattaagac ggcgcgataa ccacttatca
     8701 atccctttca tcagtagcgg cgtggtcatc attgataatg tgacagtcac caataataac
     8761 gccatctgat cgccctgaaa caggcgctga gaagaggcgg tagaaaagag cacaaaagcg
     8821 aactcgcccc cctgactcag cacgctggca aactgcatcc gttcagaact tcttattcca
     8881 tatagccgcg ccagcagata cagcgtcagc atttttatga cgaccagaat aacaacgctc
     8941 gccgccaccc acagtaaatg ggtataaagt acgccgagat ttagcgacat accgacggag
     9001 ataaagaaca gcccaagcag taaaccttta aagggatcga tagcattttc cagctcatgc
     9061 cggtattcgc tctctgccag taaaacgccg gcaatgaagg ttcccagggc catcgacagt
     9121 cccagcgcat ccataaataa ggcggcgctc aacaccagca acagcgtcgc ggcagtgaag
     9181 acctcccgca cgccagacgc agcaataaaa cgaaataccg ggcgcagcag gtaacgaccg
     9241 ccaatcagca ttaccgcgaa agccagtacc ttcattgcca ctttaaacca gtcgaaatgc
     9301 tcgtcggccg atcccgccaa taaaggcacc aacgccagcg cggggatcac cgctaaatcc
     9361 tgaaacagta agacggaaaa ccctaactgc ccggactcgc tacgattcat gcctttctcg
     9421 cgcatcagtt gtagcgccat cgccgtcgaa gacatcgcca ggccaatccc gccgacgacc
     9481 gccgcctgcc ataagaaatc agcaagcatc aataatcccg ccagcaccgc cgcgcttaac
     9541 agcacctgag cagcgccgac gccgaagata gagcgccgca gttgccaaag ccgtgacgga
     9601 ttgagttcga gaccaatgat aaacatcaga aacacgacgc ccagttcgga aaagtgcagg
     9661 atctcgtcaa catcgctgat aaatcccagc ccccacggac cgatggcgat tcccgccagc
     9721 aaatacccta gcaccgcgcc gatgcccagc ctcgcggcca gcggcaccgc cgctaccgcc
     9781 gcgaagagga acaacactcc cgcggtcaat aaatcagcac cttccatcaa tagcctcccg
     9841 cgctcacagg attcgccagc cactcgccat aggctttcgc atgactggcc agcgtctgcg
     9901 gcgactggcg gcgcgcccag tacacaataa tgggcggcat ccagtgcatc cggcacatgg
     9961 ccgcggtcag ttcaaaaggg cggagtacat cgctcattgg atagcggttt agcgcgtcat
    10021 accggtaagc gctctccggc tcgccggtcg taatcacgct acgccagtac tttcccacca
    10081 gttggtttcc ccctggtccg ctggcgaacc ctcgactcaa aacgcgatca agccattctt
    10141 tcagtaaagc cggacagcta taggtgtaaa ggggatgctg aaaaacaatg acgtcgtgct
    10201 cacgtaacag ggcttgttca tagggcgtat cgataaaaaa atcaggatag cgcgcataaa
    10261 gatcgtgcac ggttacgtta ttgtgctgta tggccggttt aagcagtacc cggttagcaa
    10321 ccgagtcctg agattccgga tgggcataca acagcaagac tttcgctggc tgagacatca
    10381 atccccctcc cggttgtttt gggtcgatac atgccattct tcaggccgct tctacgttga
    10441 cagcgtttgt tcaactcaga aacgtactcc atgtccgccg ctggggatta atgagagata
    10501 ttcttgtccc tcaccaaagg cggcctgaat gattttgtgt atcgttgttg ttttgagcta
    10561 ccattgcgct ccagcgcggc ggtacgcccg aatattacat tatcataatg ataaattaac
    10621 atagtctgaa catacggcgc cttatgattg ttttctcctc gttacaaatt cgtcgcggcg
    10681 tgcgcgtcct actggacaat gcctcggcta ccattaatcc aggccagaaa gtcggcctgg
    10741 tgggtaaaaa cggctgcggt aaatctaccc tgctggcatt gctaaaaaat gaaatcagcg
    10801 ccgatgccgg gagttttacc ctgcccggaa cctggcaatt agcgtgggtg aatcaggaaa
    10861 cacctgcgtt gcctcagcca gcgattgagt atgtcattga cggcgaccgt gaataccggc
    10921 atctggaggc gcagcttaac gacgccaacg aacgtaacga cgggcatgct atcgcctcca
    10981 tacacggtaa gctggacgcc atcgacgcat ggaccgttcg ctcgcgcgcc gccagcctgt
    11041 tacacggcct cggcttctct aacgatcagc tggaacgtcc ggtcagcgac ttttccggcg
    11101 gctggcggat gcgccttaat ctggcccagg cgctgatttg ccgttccgat ttactgctgc
    11161 tcgacgaacc gaccaaccac ctcgatctgg atgccgttat ctggctggaa aaatggctga
    11221 agagctatcc aggcaccctg attctgatct cccacgatcg cgattttctt gacccgatag
    11281 tggataaaat tatccatatc gaacagcaga ctctgttcga gtacaccggt aactacagcg
    11341 cgtttgaagt tcagcgcgcc acgcgcctgg cgcagcagca ggcgatgtat gagagtcagc
    11401 aggagcgtgt ggcgcatctg caaagctaca tcgaccgttt ccgcgccaag gccaccaagg
    11461 ccaagcaggc gcaaagccgt atcaagatgc tggagcgtat ggagttgatt gcgccggctc
    11521 atgtcgacaa cccgttccat ttcagcttcc gcgcgccgga aagcctgccg aacccgctgc
    11581 tgaagatgga aaaagtcagc gcaggttatg gcgatcgcat cattctggaa tccatcaagc
    11641 tgaacctggt gcccggctcg cgtatcggcc tgctgggccg caacggcgcg gggaaatcga
    11701 cgctgatcaa gctgctggcg ggcgaactgg aaccgttgca cggtgaaatc ggcctcgcca
    11761 aaggcattaa gctcggctac ttcgcccagc accaactgga gttcctgcgc gccgatgaat
    11821 ccccgctgca gcatatggcg cgtctggcgc cgcaggaact ggagcagaag ctgcgcgact
    11881 atctcggcgg cttcggtttc cagggcgaca aagtaacgga agagacgcaa cgtttctccg
    11941 gcggcgagaa agcgcgcctg gtactggcgc tgatcgtctg gcagcgtcca aatctgctac
    12001 tgctcgatga accaaccaac cacctggatc tcgacatgcg tcaggcgctc accgaagcgc
    12061 tgattgattt cgaaggcgca ttggtcgtcg tgtcgcacga ccgccacctg attcgctcca
    12121 ccaccgacga cctctatctg gttcacgaca aaaaggtcga accgttcgac ggcgacctgg
    12181 aggattatca gcagtggctg agcgacgtgc agaagcagga aaaccaggcc gacgacgcac
    12241 cgaaggaaaa caacgccaac agcgctcagt cacgcaaaga tcagaagcgt cgcgaagccg
    12301 agctacgcac tctaacgcag ccgctgcgta aagagattac ccgtctggaa aaagagatgg
    12361 aaaagctcaa cgcccaactg gcgcaggcgg aagagaagct tggcgacagc agcctgtatg
    12421 acccaagccg taaagcggag atgaccgagt gtctgcaact gcaggccagc gccaaatccg
    12481 ggctggaaga atgtgaaatg gcatggcttg aggcgcagga gcagcttgag cagatgatgc
    12541 agaacgacta agagcctatc ccattaggct attttattcg ccattttagg gccgggcagt
    12601 gctcgaaatc ctcacggttt ctgcgcgctg tccggcccca aactggcttc aacaattacg
    12661 cctactggga taggctctaa cgcacggggc ggacgatgaa cctgtctatc accgatgaca
    12721 ttaccttccg caagctcacc atcttcatga tgcttgtgga gaagggtaac atcgcccgca
    12781 ccgccgagac gctgcacacg ctggaagaga acgttcgttg tccactgttc gtccataaag
    12841 gcctcttcgg tactcgtccc gatataaagg ttaccgttgc ggtcggcagc accggaacag
    12901 aagcctgcgt tatgtgagtt agcggcaaag gttgccgtga tttattttcg tcagcgcgtc
    12961 gttcacgcca aataatgtaa acgtcacctc atcaacgcca agatttttca gacgcgcagt
    13021 gtgtttttta atataagcct gcgccgtttc ttcggattca aacaagtaaa tgccgccagc
    13081 ttgctggttt ttctcgcttt ctgtccagat tttccagatg aagcccggct cctcattgat
    13141 agactccgcc agcccgacca gttgctgagt catctcctcg ccaaaagggc cgctaaagtt
    13201 aaaatggatc tgtaaaagtg tcttcgacat gccttctcct tgagtcacat aactatcgtg
    13261 ttgccacact accacgatta attcggctga tgcagaggtt cacgcgattt ctgtggggta
    13321 ttgcgcgcgc cttgcatacc gccccctctg gtgaaatgag gcgcaatttt atttcgccag
    13381 acgaccaatt gaacgtaaaa tcacatattg actaatctgt gaaccttatg cgcggtatag
    13441 tattgtttcc aattatcaat tgttctggtg ctatggttga gatcacgtcc acagaaatga
    13501 ccccgcctgt caatgactcg catgaattta ttcccatgcg tggcattcgt aatcgccatt
    13561 tacaaactat gctgccacgt ttaatccgcc gcaaagtgaa gttcaacgcc cactggcagc
    13621 ggctggagct accggacggc gattttgtcg atctggcatg gagcgaagaa ccgcaacagg
    13681 caaagcataa agcgcggctg gctgggcgtg gtgatgcact ttcgcggctg tagcggcgaa
    13741 cccaaccgtc tgaatcgtat ttaccactcc ggtgaaacgg aggacggagc ctggttttta
    13801 cgctggctac agcgggagtt cggcgccgtt ccgacagccg ccgtgggcta ttcgctcggc
    13861 ggtaatatgc tggcgtgcct gctggcgaaa gaaggccgcg atattcccat cgaggcggcg
    13921 gtaattgttt ctgcgccttt cgttctcgaa gcctgtagct accacatgga caaagggttt
    13981 tcccgcgtct atcagcgtta tttgcttaat ctgttaaaag cgaatgcgtc acgcaagctg
    14041 gcggcgtatc ccgggtcgct gccggtgaat ctggcgcaac tgaaatcaat gcgccgtatt
    14101 cgcgaatttg acgacctgat caccgcgaaa attcacggct ttgccgacgc catcgactac
    14161 tatcgtcagt gtagcgccat gccgttgctt aaccagattg ctaaaccgac gctgattatt
    14221 cacgctaaag acgatccgtt tatggatcat catgtgatcc ctaaagcgga agatctgccc
    14281 ccgcaggtgg agtatcagct gactgagcat ggcggacacg taggatttat cggcggtacg
    14341 ccactgcgcc ctgaaatgtg gctggaacgc cgaattcctg actggctgac aacgtacctg
    14401 gaggcgtcat catgatcatt ccctggcagg ggctcgcccc cgacacgctg gacaacctga
    14461 tcgaaagctt tgtgttgcgc gaaggcaccg attatggtga acatgaacgt tcgcttgaac
    14521 aaaaagtcgc tgacgtaaaa cgccaactgc aatccggcga ggccgtgctg gtatggtctg
    14581 aattacatga aacggtcaat attatgccga aaaagcagtt tcgcgaataa aacgcctttg
    14641 ccgacaatac attattaata aagctcaatc atggagttgc catgtcagcc aaacatccgg
    14701 tgatagcagt aacagggtca agcggcgcgg ggaccaccac caccagcctc gcgtttcgta
    14761 aaattttcgc gcagttaaat ctgcatgccg ccgaggtgga aggcgacagt tttcatcgtt
    14821 acacccgccc ggaaatggac atggcgatcc gcaaagcgcg tgacgccggg cggcatatca
    14881 gctatttcgg gcctgaagcc aatgacttca gcctactgga acataccttt attgagtacg
    14941 ggcagacggg taaaggccag tcgcgtaaat atctgcatac ctatgatgaa gccgtaccgt
    15001 ggaatcaggt tcccggcacg tttaccccct ggcagccgct tcctgaaccg accgatgtgc
    15061 tgttttatga aggactgcac ggcggcgtcg tcaccccaca acatgatgtc gcgcgtcatg
    15121 ttgatctgtt ggttggcgtg gtgcctatcg tcaaccttga gtggattcag aaactaatcc
    15181 gcgacaccag cgagcgcgga cactcccgtg aagcggtgat ggattccgtg gtgcgttcca
    15241 tggacgacta catcaattac attacgccgc agttctcgcg tacccatatc aacttccagc
    15301 gcgtaccgac cgtcgacacg tccaatccgt tcgccgcaaa gggtattccc tcgctggatg
    15361 agagttttgt ggtgatccat ttccgcaacc tggaagggat cgattttccc tggctcctgg
    15421 cgatgctcca gggctcgttc atttctcaca ttaatacatt agtggtgccg ggcggcaaaa
    15481 tggggctggc gatggagctg attatgttgc cgctggtgca gcgattaatg gaaggcaaaa
    15541 aaatcgaata accgcggtga aatgcccgat ggcgctacgc ttatcgggcc tacgagataa
    15601 aaacgggtag gccggataag gccacgccgc catccggcat cacgtgttac gccgcaatca
    15661 cttcatacga atgggtaata ttgaccgctt tttccagcat tagcgccacc gagcaatatt
    15721 tttccgcgga gagatcgaca gcgcgcgcga cggcagcctc tttcagatcg ccgccggtaa
    15781 cgataaaatg caaattaatg tgcgtaaaca ggcgcggcgc gtcttcccgg cgctcggatg
    15841 ttagcttcac ttcgcagttg gtgacattct gacggccctt ttgcagaatt gataccacat
    15901 caatagcgct acatccgcca gccgccatta ataccatctc catcgggctc ggcgctttgt
    15961 caccggagtt accatccatt aaaatctggt ggccggagga ggactctccg aggaacgtga
    16021 gtccttcaac ccactttaca cgcgcttgca tatttcgtaa ctccaatgtt tcaattttcc
    16081 tgaaagatta cgcgcataca acaaaactcg caatggaagg cgacctgggt catgctgaag
    16141 cgagacacca ggagacacac ggcgaaagct atgctaaaac agacaagatg ctacagtaat
    16201 acattgacgt actgcatgta tgcagaggac atcacattac aggctacaat ctattttcgt
    16261 agcccccttc ccaggtagcg ggaagtatat ttttgcaacc tcagagacag tgccgttttc
    16321 tggctctgga gacagcttat aacagaggat aaccgcgcat ggtgcttggc aaaccgcaaa
    16381 cagacccggc tcttgaatgg ttcttgtctc attgccacat tcataagtac ccgtcaaaga
    16441 gcacgctgat tcaccagggt gaaaaagcag aaacgctgta ctacatcgtt aaaggctccg
    16501 tggcagtgct gatcaaagat gaagaaggga aagaaatgat cctttcttat ctgaatcagg
    16561 gtgattttat tggtgaactg ggcctgtttg aagaaggcca ggaacgcagc gcctgggtac
    16621 gtgcgaaaac cgcatgtgag gtcgctgaaa tttcctacaa aaaatttcgc caattaatcc
    16681 aggtcaaccc ggatattctg atgcgcctct cttcccagat ggctcgtcgc ttacaagtca
    16741 cctctgaaaa agtaggtaac ctcgccttcc ttgacgtcac cgggcgtatc gctcagacgc
    16801 tgctgaatct ggcgaaacag cccgatgcca tgacgcaccc ggatgggatg cagatcaaaa
    16861 tcacccgtca ggaaatcggc cagatcgtcg gctgctcccg cgaaaccgtt ggtcgtattt
    16921 tgaaaatgct ggaagatcaa aacctgatct ccgcgcatgg caagaccatc gtcgtctacg
    16981 gcacccgtta atcccgtcag aatggcgcgt tttatcatgc gccatttttg tttgcatcga
    17041 tgtggcgaag actgatttat cacccagaga ttaattacgc actacggcaa acgctggtgc
    17101 tgtgcctgcc tgtggctgtt ggtttattga taggccagct acacctgggc ttgcttttct
    17161 ctctcgttcc cgcctgctgc aacattgcag gtctggatac cccgcacaaa cgctttttta
    17221 aacgcctgat catcggcgcg tcgctgttcg ccggatgcag tctggtaacg caacttctgc
    17281 tggcggaatc catccccctg ccgttgatcc tgaccgggct cacgctggtg cttggcgtga
    17341 cggcggaaat tagcccgctt cacgcgcggc tactgccagc gtcgctgatt gccgccatct
    17401 ttaccctgag ccttgcggga tacatgcccg tctgggagcc gctgctcatt tatgcgctgg
    17461 gcacgctatg gtacggcgtg tttaactggt tttggttctg actatggcgc gaacagccgc
    17521 tgcgcgagtc attgagtttg ttataccgtg aactggccga ttattgtgaa gcgaaataca
    17581 gcctgctcac ccaacatatc gatccggaaa aagcgctgcc tcccctgctg atacgccagc
    17641 aaaaagcggt cgatctcatt acccagtgtt accaacagat gcatatgctt tcggcgcaca
    17701 acaataatga ttacaagcgt ctactacggg cttttcagga agcgatggat ttgcaggagc
    17761 acatctccgt cagcttgcat cagccggaag aggtacagaa actggtagaa cgcagccatg
    17821 cggaagaggt gattcgctgg aatgcgcaaa cggtcgccgc ccgtctgcgc gtgctggcgg
    17881 atgacattct ttatcatcgt ctgccgacgc gcttctccat ggaaaaacag attggcgctc
    17941 tggagaagat cgctaatcag catcctgaaa atccggtagg ccagttctgc tattggcact
    18001 tcagtcgaat cgcccgtgtg ctgcgtactc agcggccgct gtacgcccgc gacctgatgg
    18061 ccgataaaca gcgtcgtctg ccgctacttc cggcgctgaa aaattatatg tctctaaaat
    18121 cgccggcgct acgcaacgcc ggacgcatca gcgtgatgat gagcatcgcc agtctgatgg
    18181 gcagcgcgtt gcacctgcct aaaccgtact ggatcctcat gacggtgctg tttgtcaccc
    18241 aaaacagcta tggcgcgacg cgcgtacgta ttctgcaccg ttcggtcgga acgctggtcg
    18301 gcctggtgat tgccggcgtc acgctgcact tacatattcc cgaaagcatt acgctggcgg
    18361 tcatgctggt actaacgctg gcaagttatc tgattattcg taaaaactac ggctgggcga
    18421 cggtcggctt tacggtgacg gcggtataca ccatccagtt actgacgtta aacggagagc
    18481 agtttattgt gccgaggctg atcgatacgc tgattggctg tttaattgcc tttggcggca
    18541 tggtctggct gtggccgcaa tggcaaagcg ggctattacg taaaaacgcc catgatgcgc
    18601 tggaagccga tcaagaagct atccgactga tcctcagtaa cgatccgcag gccaccccgc
    18661 tcgcttatca aagaatgcgg gtcaaccagg cgcataacac gttattcaac tcgttaaatc
    18721 aggcaatgca ggaacccgga ttcaataccc actatctgtc ggatatgaaa ctgtgggtca
    18781 cgcacagcca gtttattgtc gagcatatca acgctatgac gacgctggcg cgggaacaca
    18841 ccatgctgac gcctgatctg gcgcagcgct atctggaatc ttgcgagatt gcgattcagc
    18901 gctgccagca gcgcctagag tacgacaggc caggcggctc cggcgatgtc aatattctgg
    18961 agtcgccgga catgccgtca catggcttat tgagcactct ggaacaacat ttacagcgca
    19021 tcattggcca tctgaacacc atgcacacca tttcgtcgat ggcctggcgt cagcgtccgc
    19081 atcacggtat ctggctgagt aagcggctac gggatacaaa aggttaagac cgactgccgg
    19141 atgcgctacg cttatccggc aatccgccat caggccacca ccttccctac cgcctgcgca
    19201 aagcgctgca ttccttcatt gatatccgcc tcttccacca ccagcgacgg ggcaaaacgc
    19261 atcacgtcgg ctccggcatt gagcaccatc acgccggcct ccgcgcctgc gtacagaaaa
    19321 tcgcgcgccc gacctttgta cttcggcttc agttccgcgc caatcagcag ccccatgccg
    19381 cgaatatcgc tgaaaatgtc aaattgctcg tcaatcgcct gcaaatgttg cacaaactgt
    19441 tgccgcttag tgtgaatgcc ttgtagtacc tctggcgtat taataatatc gaatgccgcg
    19501 ccagccaccg cacaggccag cggattgccg ccataggttg aaccatgcga accgacatgg
    19561 aaggccgagg cgatctcctg cgtggtcagc atggcgctca ccggaaaacc gccgcctaac
    19621 gctttggcgc tggtgaggat atccggcgtg acgccgtagt gcatataggc aaacaggtct
    19681 ccggtgcgcc ccatcccaca ctgcacttca tcaaacacca gcaacgcctg atgcttgtca
    19741 cacaggtcgc gtaacccttt gaggaattcc ggtgtagccg cctgcacgcc gccttcaccc
    19801 tgaatcggct cgactaccac cgcgcaggtg tggtcatcca ttaccgcttt caccgcatga
    19861 agatcgttga agggaacgtg aataatatcg gcgggtttcg gcccaaagcc gtcggaatat
    19921 ttcggctgcc cgcctacaga gacggtaaac aaggaacggc catgaaaggc gttctggaag
    19981 gcaatgattt tcgttttgaa cgggctatgg cgcacgcagg cataatgacg cgccagttta
    20041 aaagcggttt cgttcgcttc ggtgccggaa ttcataaaca gcacgcgctc ggcaaacgtg
    20101 gcgtcgatca gtttacgtcc cagacacaac gccggttcat tggtaaaaac gttactggta
    20161 tgccacaagg tttccccctg ggatttcagc gcctcgacca gtgccggatg gcaatggccc
    20221 agcgcagtca ctgcaatccc gccggcgaaa tcgatatact ctttgccctg ctgatcccat
    20281 acgcggctgc ctttaccttt gaccggaata aagtccgccg gtgcataaac aggcagaatt
    20341 acctcatcaa aagttgcgcg cgtaatagcc gtttgttcag ttgccatatc attaccaccc
    20401 ggttaagtag aaatgccagt gaaattataa tcacaaaata tgaataaaaa atcactcaat
    20461 agcaaccaca aatcaacgcc ggaggaaatt ttccagcaga gcgtgtcctt gttcgctgag
    20521 aatactttcc gggtggaact gcacgccttc cagatcccac tcgcggtggc gaatgcccat
    20581 aatctcctgc gtttcgctcc aggcggtgat ctcaaaacac tcaggcaacg tggcagggtc
    20641 gacaatcagc gagtggtaac gtgtcacggt taacgggctg ggcaatcccc gaaacacgcc
    20701 ctgtccatta tgcgtaacag gtgacgtttt accgtgcatc actttcgctg cccgcaccac
    20761 cgacgcgcca aaggcctgcg ccatcgcctg atgacccagg caaacgccca gcatcggaat
    20821 acgtccggca taatggcgga tgaccgccag tgaaatgcca gcgtcatttg gcgtacaggg
    20881 gccaggagag ataacgattt tttgcgggtt caaagcgtca atgtgcgcca gcgtcagcgc
    20941 atcattgcgc cgaacctgca cttccgcgcc cagttcacaa aaatactggt agaggttcca
    21001 ggtaaaggaa tcatagttat cgataagcag gatcatggcg gctccgggtc agtagaaccg
    21061 ccctatttta ctcagtttcg cgagcttcgc ttatcgcttt ctgaaaaatc gcccgcaaag
    21121 cggagagatc gcccatcgcg ccgctctggt tcgcctgatt ccatgtttca accgcaatac
    21181 cttgccaact cagcgcgtag cctgcatgta gcgccagttg ttcaaagaag atgcgctgcg
    21241 ccagcccgct ccccaaacga aacggatgaa gcacattaat ttcacagtag taatgcgcca
    21301 gccgctcgac aaacttctcg tgcgtcagac caaccaggta gccctcttct tccagatcct
    21361 gcatcagggc attgccctct ttttcgatat aggcaaagtg gcagaaacgg gtatcgccct
    21421 ggtaaatatc gacctcccgc agttgccctg cccagtcgaa aatatcctga tagagctggc
    21481 gatgaatcgc gcacagatga ggcaagccgc gtaccagcgg ccccagttca atcgtagcgg
    21541 cgcggagcgc ggtcatttcg tatgccgctt gcgccagtcg ctgggcctga tgaatcccca
    21601 gccgattacg catcacattc agccccggat agaggtacgg atcgcgccct tcgccaaatt
    21661 tatcgctcat agtgcctccg aagctcgtca agacgtgcca gcgcttcatc ggcggtcagg
    21721 gttactaagg ggatctcaat accttcgaga cggcggcttt gctggaagtt aacgttgcgc
    21781 cgctgttccc aaaagcgtga cttttgttta tcggtaagtt tcttcacctg gcctccctga
    21841 atatgcctgt gattgaccac aagtataagc agcaatttca ggttacgctg agacagggag
    21901 aaaacgcggg cggctcgcac ccgcgcaggc atgttttatg gcaggacttt cgcggaaagg
    21961 ataacgactg gttttgtcgg cacattctga taaggcccga catcgtgcgt cggtacctgt
    22021 gagattttat cggcgacatc catacctttt accactttac caaataccgc atagccaaag
    22081 tcgcgctggc cgtggtcgag aaaagcgtta tccgcgacgt taataaagaa ctggctggtg
    22141 gcgctgtctt tatctgcggt gcgagccatc gcgatcgtgc cgcgagtatt acgcagaccg
    22201 ttgtcggctt cattcttaat aggcggattc ggtttcttct gctgcatctg ctcgttaaaa
    22261 ccaccaccct gaatcataaa gccaggaata acgcggtgaa acgtagtgtt gttatagaaa
    22321 ccactgttga cgtaatcgac aaagtttttc acagaaaccg gcgctttctg gctgttcagc
    22381 tccagctcaa tattcccggc ggaggtggtt aacagcacat gaggatcacc ttttgctgcc
    22441 aacgctacgg gagaaagagc agaaagagcg aaaacagctg cgacagccgc cagagtcgat
    22501 ttgagcatga gatttcctta aagagagcag aaataaagca agtggaatga ttctaaagag
    22561 ccttcctggg ccaggccagc cctttaccta attttacgta catgaaacaa atgtaacgtt
    22621 acgacgcaac gccttgtcct tgcaatatga tgtgacaaac atcacattaa aaaatgtaat
    22681 gaacattact atcactaata attatttaaa tacatcacaa aagcgcttaa aatctgcccg
    22741 cttaacgcgc cctccacgcg cttcacttct cttcaaggcc agacatgact aacagcaacc
    22801 gcatcaagct cacatggatc agctttcttt cctacgccct gaccggggcg ctggtgattg
    22861 tcaccgggat ggtgatggga aatatcgcag actattttca gttgcccgtt tccagcatga
    22921 gtaacacctt tactttcctg aatgccggga ttttgatctc gatcttcctc aatgcgtggt
    22981 tgatggaaat cgtcccgctg aaaacacagc tacgctttgg ttttatcctg atggtactgg
    23041 cggtggccgg gctgatgttc agccatagcc tggcgttgtt ctcagcggcg atgtttgtgc
    23101 tggggctggt cagcgggatc accatgtcga ttggcacctt cctgattacg caactgtatg
    23161 aagggcgtca gcgcggttcc cgactgctgt ttaccgactc cttcttcagc atggcgggga
    23221 tgatttttcc tatggtcgcc gccttcctgc tggcgcgtag tattgagtgg tactgggtct
    23281 acgcctgcat cggcctggtc tacctggcga tttttatcct gaccttcggc tgtgaatttc
    23341 cggcgctggg taaacatgcg cagcactctc aggcgcctgt cgtcaaagaa aaatggggca
    23401 ttggcgtact gtttctggcc gtcgccgcgc tgtgctatat cctcggtcaa ttgggcttta
    23461 tctcctgggt gccggaatac gccaaaggcc tcggcatgag cctgaatgac gccggggcgc
    23521 tggtgagtga tttctggatg tcctatatgt ttggcatgtg ggcgttcagc tttatcctgc
    23581 gctttttcga tctgcaacgc atcctgaccg tactggcggg tatggcggcg atactgatgt
    23641 atctgtttat taccggcacg caggcgcata tgccgtggtt tattctgacg ctgggcttct
    23701 tctccagcgc catttatacc tccatcatta cgctgggatc gcagcaaacg aaagtggcct
    23761 cgcctaagct ggttaacttt attctgacct gcggcaccat cggaacgatg ctgaccttcg
    23821 tcgtcaccgg cccgattgtg gctcacagcg gcccacaggc ggcgttactc accgcgaatg
    23881 gtctgtatgc ggtggtcttt gtgatgtgct ttgcgctcgg ctttgtctcc cgtcatcgcc
    23941 agcatagttc gccagcggcg cattaataat gattgccgga tggcgacgcg atgcgtctta
    24001 tccggcctac agcgtaagct gttggtaggc cggataaggc gacgtcgccc tccggcactc
    24061 tatccccccc tgacgaggta ggcttgttgg tctaaaaacc cctcattttg tatgttattt
    24121 gtacaaacct gaaaagcctg acaattccgc cacttataaa aacccagaca aatcagccat
    24181 atacccatta agaggtatat aaaggtgaat ttgatttaca tcaataagcg gggttgctga
    24241 atcgttaagg taggcggtaa tagaaaagaa atcgaggcaa aaatgagcaa agtcagactc
    24301 gctattatcg gtaatggtat ggtcggccac cgctttattg aggatctcct tgataaatcc
    24361 gacgctagcc tgttcgacat taccgtgttc tgtgaagaac cccgtaaagc ctatgaccgt
    24421 gtccacctgt catcctactt ctctcaccac accgcggaag agctctctct ggtgcgtgaa
    24481 ggattttacg agaagcacgg cgtaaaggta ctggttggcg aacgcgcaat taccattaac
    24541 cgtcaggaga aagtgattca ctccagcgcg ggtcgtaccg tttattatga caagctgatc
    24601 atggcgaccg gttcctatcc gtggattccg ccgattaaag gctccgaaac ccaggattgc
    24661 ttcgtttacc gtaccattga agacctcaac gctatcgaag cctgcgcccg ccgcagcaag
    24721 cgcggggcgg tggtcggcgg cggtctgctg gggctggaag ccgctggcgc gctgaaaaac
    24781 ctcggcgtgg aaacgcacgt cattgaattt gcgccaatgc tgatggcgga acaactcgat
    24841 caaatgggcg gcgagcagct acgtcgcaag atcgaaagca tgggcgtgcg tgtacacacc
    24901 agtaaaaaca cgcaagagat tgttcagcag ggtaacgaag cgcgtaagac tatgcgtttt
    24961 gccgatggca gcgagttgga agtcgatttt atcgtcttct ctaccggtat tcgcccccgc
    25021 gacaagctgg ctacccagtg cggtctggcc gtcgcgcagc gcggcgggat cgtgattaac
    25081 gacacctgcc agacgtccga cccggatatc tacgctatcg gcgagtgcgc cagttggaac
    25141 aaccgcgttt acggtctggt cgcaccgggc tataaaatgg cccaggtcgc cgttgaccat
    25201 atcctcggca gtgaaaacgc ctttgaaggc gcggatctca gcgccaaact gaagctgctg
    25261 ggcgtggacg tcggcgggat tggcgatgcg catggccgca cgccgggcgc gcgtagctac
    25321 gtttacctcg atgaaagcaa agaagtctac aaacgtctta ttgtcagcga agataacaaa
    25381 acgctgctcg gcgcagtact ggtcggcgac accagcgatt acggcaattt gctgcaactg
    25441 gtactgaacg ccatcgaact gccggaaaac ccggattcgc tgatcctgcc gtcgcacgcg
    25501 agcagtggta aacccgctat cggcgtggat aaactgccgg acagcgcgca gatctgctcc
    25561 tgcttcgatg tgactaaagg cgatctgatc gctgctatca ataaaggctg ccataccgtg
    25621 gcagcgctga aagcggaaac caaagccgga accggctgcg gcggctgcat cccgctggtg
    25681 acgcaggtac tgaacgccga actggcgaaa cagggtattg aagtcaacaa caacctgtgc
    25741 gagcactttg cttattctcg tcaggaactg ttccacttaa tccgcgtgga aggtatcaaa
    25801 acctttgaag aactgctgac gaaacacggt aaaggctacg gctgcgaagt gtgtaagcca
    25861 accgtcggtt cgctgctggc gtcgtgctgg aacgaataca tcctcaaacc gcagcacacg
    25921 ccgctacagg atactaacga taacttccta gcgaatattc agaaagacgg cacctactcg
    25981 gtgatcccgc gctcggcggg tggtgaaatc acgccggaag gtctggtggc cgtgggtcgt
    26041 atcgcccgcg agtttaacct ctataccaaa atcaccggtt ctcagcgtat cggtctgttc
    26101 ggcgcgcaaa aagacgatct gccggaaatc tggcgtcagt tgattgaagc cggtttcgaa
    26161 accggtcacg cgtacgccaa agcgctgcgg atggcgaaaa cctgcgtcgg cagcacctgg
    26221 tgccgctacg gcgtgggcga cagcgtcggt ttcggcgtgg agctggaaaa ccgctacaaa
    26281 ggcattcgta ccccgcacaa aatgaaattc ggcgtctccg gctgtacccg tgaatgtgcg
    26341 gaagcacagg gtaaagatgt cggtatcatc gccactgaga aaggctggaa cctgtacgtt
    26401 tgcggtaacg gcgggatgaa accgcgtcat gcggatctgc tggcagccga tctcgatcgc
    26461 gacacgctga tcaagtacct cgaccgcttt atgatgttct acatccgtac cgccgataag
    26521 ctgacgcgta ccgcgccgtg gctggataac ctggaaggcg gcatcgaata tctgaagtcg
    26581 gtcattatcg acgataagct gggcctgaac gaacatctgg aagaagagat ggcgcgcctg
    26641 cgcgcagcgg tggtctgcga gtggacggag accgtcaaca cgccagcggc gcaggttcgt
    26701 ttcaaacact tcatcaacag cgacaaacgc gacccaaatg tccaggttgt gcctgaacgc
    26761 gaacagcatc gtccggccac gccgtatgaa cgcatcccgg tcactctggt ggaggaaaac
    26821 gcatgagcca gtggcaaaac atctgcaaaa ttgatgacat cctgccggga accggcgtct
    26881 gcgcgctgtc aggcggcgag caggtggcga ttttccgtcc ttaccatagc gatcaggtgt
    26941 ttgcgatcag caacatcgac ccgttctttg aggccagtgt gctgtctcgt gggctgattg
    27001 cggaacacca gggcgaactg tgggtcgcca gcccgttgaa aaagcagcgc tttcgtttaa
    27061 gcgacgggct gtgcatggaa gatgagcagt tctctgtgaa gcattacgac gcgcgggtaa
    27121 aagacggcgt ggtgcagttg cgcggttaat tatttttggg aggcgcaacg cctccccttt
    27181 tttgacgtat ttgtaggtct tttattggta ggcctgataa gcgtagcgcc atcaggcaat
    27241 tgcaaaagca cattgccgga tggcggcata aacgccttat ccggcctacg gttacgattt
    27301 ttttgttttt tatacttcaa ggataatcaa atgtttacag acactattaa taagtgtgcg
    27361 gctaacgctg cgcgcatcgc acgcctgtcg gcgaataatc cgctcggctt ctgggtcagt
    27421 tcggcaatgg ccggggctta tgtcggtctc ggcatcattc ttattttcac cctcggcaat
    27481 ctgctcgacc cgtccgtgcg tcctttggtg atgggagcca ccttcggtat cgccttaacg
    27541 ctggtcatca tcgccggttc cgaactgttt accggccaca ccatgttcct gacgctgggc
    27601 gtcaaagcgg gcaccatcag ccacggtcaa atgtgggcta tcctgccgca aacctggctc
    27661 ggcaacctgg ttggttccgt gtttgtcgcc ctgctttaca gctggggcgg cggcagtttg
    27721 ttgccggtcg ataccagtat cgttcactca gtcgcgctgg cgaaaaccac cgcgcccgcc
    27781 acggtactgt tcttcaaagg cgcgctgtgt aactggctgg tttgtctggc aatctggatg
    27841 gcgatccgca ccgaaggcac ggcaaaattt cttgctatct ggtggtgtct gctggcgttt
    27901 atcgcttccg gctacgagca ctccgtcgcg aatatgacgc tgttcgccct ctcctggttt
    27961 ggccatcaca gcgatgccta taccctgtcc ggaatcggac acaatctgtt atgggtcact
    28021 ctgggcaata ctttgtccgg cgtcgtgttc atgggattgg gttattggta tgctacgccg
    28081 aaatcggagc gccctgttcc gcaaaaaacc aaccaaatta aggctacagc caaccattaa
    28141 ggggtaatgt cgtggaccat ttgcctatat tttgtcaatt gcgcgaccgc gactgtctga
    28201 tcgtcggcgg tggcgatgtc gcagaacgca aagcacggtt actgctggaa gcaggcgcac
    28261 gtttaacggt caatgcgcta acatttattc cgcagttcac cgtatgggta aatgaaggca
    28321 tgttgactct ggttgagggg ccgttcgacg aaacgcttct cgactcgtgt tggctggcga
    28381 tcgcggccac tgacgacgat accgtcaacc agcgcgtcag cgaagcggcg gaatcacgcc
    28441 gtatcttctg caacgtggtg gatgcgccga aagccgccag ctttatcatg ccctccatta
    28501 tcgaccgctc gccgctgatg gtcgccgtct cctccggcgg cacctccccg gtgctggcgc
    28561 gtctgctgcg cgagaaactg gaatcgctgc tgccgcagca tctggggcag gtcgcgcgct
    28621 atgccggaca gctccgcgcc cgagtgaaaa agcagtttgc caccatgggc gaacgtcgtc
    28681 gcttctggga aaaatttttc gtcaatgacc ggctggcgca gtcgctggcg aatgccgatg
    28741 agaaagcggt taacgcgaca actgaacacc tgtttagcga gccgctggat caccgtggcg
    28801 aagtcgtgct ggtcggcgcc gggccgggcg atgccgggct gcttacgctg aaaggattac
    28861 aacaaatcca acaggcggat atcgtggttt acgatcgcct cgtttccgac gacattatga
    28921 acctggtacg ccgcgatgcc gatcgggtct ttgtggggaa acgcgcgggt taccactgcg
    28981 tcccacagga ggaaatcaac cagatcctgc tgcgtgaagc gcaaaaaggt aaacgcgtgg
    29041 tacgcctgaa aggcggcgat ccctttatct ttggtcgcgg cggcgaagag ctggaaacgc
    29101 tgtgtcatgc cggtattcct ttctcagtag taccggggat taccgcggct tccggctgct
    29161 ccgcctactc cggtattccg ctaacccatc gcgattacgc acagagcgta cgtctggtca
    29221 cgggtcacct gaaaaccggc ggcgagctgg actgggaaaa cctggcggca gaaaaacaga
    29281 cgctggtgtt ctacatgggg ctgaatcagg cagcgactat ccaggaaaaa ctgatcgcat
    29341 tcggtatgga ggccaatatg ccggttgcgc tggtggaaaa cggtacctcc gtaaagcaac
    29401 gcgtcgttca cggtgtgctg acgcagcttg gtgaattagc gcaacaggtt gaaagcccgg
    29461 cgctgattat cgttggtcgc gtggtagcct tacgcgataa attaaattgg ttctctaa
//
LOCUS       DAJVBX010000027        29162 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.027, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000027 DAJVBX010000000
VERSION     DAJVBX010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 29162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29162
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.027"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..916
                     /gene="iaaA"
                     /locus_tag="OPV72_001096"
     CDS             <1..916
                     /gene="iaaA"
                     /locus_tag="OPV72_001096"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HCR9913460.1"
                     /translation="GGAGAIARAQMSHEQELRYIQALSEIVESGQKMLEAGDSALDVV
                     TEAVRLLEACPLFNAGIGAVYTRDGTHELDACVMDGNTLKAGAVAGVSHVRHPVLAAR
                     LVMERSPHVLMVGEGAENFAFSQGMARVSPDIFSTPARYEQLLAARAAGEMALDHSGA
                     PLDETKKMGTVGAVARDKFGNLAAATSTGGMTNKLPGRVGDSPLVGAGCYANNASVAV
                     SCTGTGEVFIRTLAAYDIAALMEYGGLSLADACERVVMEKLPALGGSGGLIAVDHEGN
                     VALPFNSEGMYRAWGYAGDTPTTGIYRE"
     gene            927..2798
                     /gene="gsiA"
                     /locus_tag="OPV72_001097"
     CDS             927..2798
                     /gene="gsiA"
                     /locus_tag="OPV72_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter ATP-binding protein
                     GsiA"
                     /protein_id="HCR9913461.1"
                     /translation="MPHSDELDSRDVLSVSGLNIAFHHEGQQVDAVRNVSLRLKRGET
                     LTIVGESGSGKSVTALALMRLIEQSGANVRCGEMLLRRRNRQVIELSEQSDAQMRRVR
                     GADIAMIFQEPMTSLNPVFTVGEQIAESIRLHQGASHEEALAEAKRMLDQVRIPESQA
                     ILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQQEM
                     SMGVIFITHDMGVVADIADRVLVMYQGEAVETGSVEQIFHAPTHPYTQTLLAAVPQLG
                     AMRGHSLPRRFPLISADEPALYESQIEQDTVVEGEPILQVRGLVTRFPLRSGLFNRVT
                     REVHAVENISFDLWPGETLSLVGESGSGKSTTGRALLRLVESRQGEIIFNGQRIDTLS
                     AGKLQPLRRDIQCIFQDPYASLDPRQTVGYSIMEPLRIHGLGQGDAAAKRVAWLLERV
                     GLRPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADEAVSALDVSVRGQIINLLLD
                     LQREMGIAYLFISHDMAVVERISHRVAVMYLGQIVEMGPRRAVFENPQHPYTRKLMAA
                     VPVADPSRHRPRRVLLSDDIPSNIHKRGEETPAVSLQLVGPGHYVARPLQDNALSRL"
     gene            2831..4369
                     /gene="gsiB"
                     /locus_tag="OPV72_001098"
     CDS             2831..4369
                     /gene="gsiB"
                     /locus_tag="OPV72_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter substrate-binding
                     protein GsiB"
                     /protein_id="HCR9913462.1"
                     /translation="MTQFITHKWLAALGLASSIAAFPALAAKDVVVAVGSNFTTLDPY
                     DANDTLSQAVAKSFYQGLFGLDKDMKVKNVLAEGYTVSDDGLTYTITLRQGVKFQDGA
                     DFNAAAVKANLDRASNPDNHLKRYNLYKNIAKTEVVDPATVKITLKQPFSAFINILAH
                     PATAMISPQALEKYGKDIGFHPVGTGPYQLETWNQTDFVKVKKFAGYWQQGLPKLDSI
                     TWRPVTDNNTRAAMLQTGEAQFAFPIPYEQAALLAKNKNLELVASPSIMQRYISMNVT
                     QKPFDNPKVREALNYAINRQALVKVAFAGYATPATGVVPPSIAYAQSYQPWPYDPAKA
                     RELLKEAGYPDGFSTTLWSSHNHSTAQKVLQFTQQQLAQIGIKARITAMDAGQRAAEV
                     EGKGQKESGVRMFYTGWSASTGEADWALSPLFASQNWPPTQFNTAFYSNKQVDSDLAA
                     ALKTNDPQEKTRLYKEAQDIIWKESPWIPLVVEKLVSAHSKNLTGFWIMPDTGFSFDD
                     ADLK"
     gene            4430..5350
                     /gene="gsiC"
                     /locus_tag="OPV72_001099"
     CDS             4430..5350
                     /gene="gsiC"
                     /locus_tag="OPV72_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter permease GsiC"
                     /protein_id="HCR9913463.1"
                     /translation="MLNYVLKRLLGLIPTLLIVAVLVFLFVHLLPGDPARLIAGPEAD
                     AQVIALVRQQLGLDQPLHVQFWHYITHVLQGDFGTSMVSRRPVSEEIASRFLPTLWLT
                     ITSMIWAVLFGMAIGIAAAVWRNRWPDRVGMTLAVTGISFPAFALGMLLMQIFSVDLG
                     WLPTVGADSWQHYILPSLTLGAAVASVMARFTRSSFVDVLSEDYMRTARAKGVSETWV
                     VLKHGLRNAMIPVVTMMGLQFGFLLGGSIVVEKVFNWPGLGRLLVDSVDMRDYPVIQA
                     EVLLFSLEFILINLVVDVLYAAINPAIRYK"
     gene            5353..6264
                     /gene="gsiD"
                     /locus_tag="OPV72_001100"
     CDS             5353..6264
                     /gene="gsiD"
                     /locus_tag="OPV72_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter permease GsiD"
                     /protein_id="HCR9913464.1"
                     /translation="MRLFNWRRQAILHAMPVVKPDQIRTPWREFWRRFRRQHVALVAG
                     GFVLALILVAIFARWLTPYDAENYFDYDSLNNGPSLQHWFGVDSLGRDIFSRVLVGAQ
                     ISLAAGVFAVFIGAIIGTVLGLLAGYYEGWWDRFIMRICDVLFAFPGILLAIAVVAVL
                     GSGIANVIVAVAIFSIPAFARLVRGNTLVLKQQTFIESARSIGASDTTILFSHILPGT
                     VSSIVVFFTMRIGTSIISAASLSFLGLGAQPPTPEWGAMLNEARADMVIAPHVALFPA
                     VAIFLTVLAFNLLGDGLRDALDPKIKG"
     gene            complement(6355..7680)
                     /gene="rimO"
                     /locus_tag="OPV72_001101"
     CDS             complement(6355..7680)
                     /gene="rimO"
                     /locus_tag="OPV72_001101"
                     /EC_number="2.8.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     RimO"
                     /protein_id="HCR9913465.1"
                     /translation="MSNVTHQPKIGFVSLGCPKNLVDSERILTELRTEGYDVVPHYDD
                     ADMVIVNTCGFIDSAVQESLEAIGEALNENGKVIVTGCLGAKEDQIREVHPKVLEITG
                     PHSYEQVLQHVHHYVPKPKHNPFLSLVPEQGVKLTPRHYAYLKISEGCNHRCTFCIIP
                     SMRGDLVSRPIGDVLSEAKRLVDAGVKEILVISQDTSAYGVDVKHRTGFHNGEPMKTS
                     MVSLCEQLSKLGVWTRLHYVYPYPHVDDVIPLMAEGKILPYLDIPLQHASPRILKLMK
                     RPGSVDRQLARIKQWREICPELTLRSTFIVGFPGETEEDFQMLLDFLKEARLDRVGCF
                     KYSPVEGAGANELPDQVPEEVKEERWNRFMQLQQQISAERLQEKVGREILVIVDEVDE
                     EGAIGRSMADAPEIDGAVYLNGETNVKPGDIVRVKVENADEYDLWGSRV"
     gene            7911..8294
                     /gene="bssR"
                     /locus_tag="OPV72_001102"
     CDS             7911..8294
                     /gene="bssR"
                     /locus_tag="OPV72_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm formation regulator BssR"
                     /protein_id="HCR9913466.1"
                     /translation="MVVDRLRTDLLNKLINARIDLAAYLQLRKAKGYMSVSESDTLRD
                     NFFELNRELHDHALRQGLHLDQEEWNALRRAEGALAAAAVCLMSGHHDCPTFIAVNAD
                     KLENCLTTLTLSIQSLKAHSPLTQV"
     gene            8413..9534
                     /locus_tag="OPV72_001103"
     CDS             8413..9534
                     /locus_tag="OPV72_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001252732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PQQ-dependent sugar dehydrogenase"
                     /protein_id="HCR9913467.1"
                     /translation="MRRILLAIVSFSLFSSWANANLAPVNVEVLQTRLDHPWSLAFLP
                     DNRGMLITLKGGQLRHWQTGRGLSDPLAGVPKVWANGQGGLLDVVLAPDFAQSRRVWL
                     SYAEADREGNAGTAAGFGRLSDDFQRLEHFRTVFRQMPKLSTGNHFGGRMVFDAQGFL
                     FIALGENNQRATAQDLDKLQGKLVRLTGQGEIPPDNPFVHQAGARPEIWSYGIRNPQG
                     LAINPWSGALWLHEHGPRGGDEINIPEKGKNYGWPLATWGVNYSGLKVPEAKGEIVEG
                     TEQPVYYWKDSPAISGMAFYASDVFAPWRHKLFIGALKDKEVIVMRVDGNTVTEEGRI
                     LGDRKQRIRDVRVGPDGYLYVLTDESDGQLLKVSPAATR"
     gene            complement(9531..10157)
                     /locus_tag="OPV72_001104"
     CDS             complement(9531..10157)
                     /locus_tag="OPV72_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase family protein"
                     /protein_id="HCR9913468.1"
                     /translation="MITLWGRNNSTNVKKVLWTLEELELPYDQILAGGKFGVNQDADY
                     LAMNPNGLVPLLKDDETDLLLWESNAIVRYLAAQYGQNRLWVDNPARRAEGEKWMDWA
                     NQTLSPAHRVILMGLVRTPPEKRDQAAIEAGIEKCDSLFALLDDALAHQPWFSGDNFG
                     TGDIAIAPFVYNLLNVGLKWTPRPNLQRWYQQLTERPAFRKVVMIPVT"
     gene            10401..11603
                     /gene="dacC"
                     /locus_tag="OPV72_001105"
     CDS             10401..11603
                     /gene="dacC"
                     /locus_tag="OPV72_001105"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine-type D-Ala-D-Ala carboxypeptidase"
                     /protein_id="HCR9913469.1"
                     /translation="MTQYASSLRSLAAGSVLLFLFASPVKAEEQTIAPPGVDARAWIL
                     MDYASGKVLAEGNADEKLDPASLTKIMTSYVVGQALKAGKIKLTDMVTVGKDAWATGN
                     PALRGSSVMFLKPGDQVSVADLNKGIIIQSGNDACIALADYVAGSQESFIGLMNAYAK
                     RLGLTNTTFQTVHGLDAPGQFSTARDMALLGKALIHDVPDEYAIHKEKEFTFNNIRQP
                     NRNRLLWSTNLHVDGMKTGTTAGAGYNLVASATQGDMRLISVVLGAKTDRIRFNESEK
                     LLTWGFRFFETVTPIKPDATFVTQRVWFGDKREVNLGAGDAGSVTIPRGQLKNLKASF
                     TLNEPQLTAPLKKGQVVGTIDFQLNGKSIEQRPLMVMENVEEGGFFSRMWDFVLMKLH
                     QWFGSWFS"
     gene            complement(11649..12407)
                     /gene="deoR"
                     /locus_tag="OPV72_001106"
     CDS             complement(11649..12407)
                     /gene="deoR"
                     /locus_tag="OPV72_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional repressor DeoR"
                     /protein_id="HCR9913470.1"
                     /translation="METRRDERIGQLLQALKRSDKLHLKEAATLLGVSEMTIRRDLNH
                     KSAPVVLLGGYIVLEPRSASHYLLSDQKSRLVEEKRRAAQLAAGLVQAHQTVFIDCGT
                     TTPWIIEAIDNDLPFTAVCYSLNTFLALQDKPHCRAILSGGEFHASNAIFKPLDFHET
                     LNNICPDIAFYSAAGVHTSKGATCFNLEELPVKHWAMTMAQSHVLVVDHSKFGKVRPA
                     RMGELSRFDTIISDRRPDEAFVAYAKAQQITLMY"
     gene            complement(12479..13087)
                     /gene="ybjG"
                     /locus_tag="OPV72_001107"
     CDS             complement(12479..13087)
                     /gene="ybjG"
                     /locus_tag="OPV72_001107"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HCR9913471.1"
                     /translation="MLENLNNSLFYFINATPDSAQWIISLAIFIAKDVINIVPLLAVV
                     LWLWGPRDRVCAQRQLIVKIGIALIISLAVSWTMGHLFPHDRPFVDHIGYNFLHHAAD
                     DSFPSDHGTVIFTFALAFLFWHRLWSGIVMMAIAMTIAWSRVYLGVHWPLDMIGALLV
                     AMLGCLSAQLIWQWYGAPLYQALQRCYRFCFALPIRKGWVRD"
     gene            13400..14632
                     /locus_tag="OPV72_001108"
     CDS             13400..14632
                     /locus_tag="OPV72_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR9913472.1"
                     /translation="MQNRLQSGGRLGRQALLFPLCLVLYEFSTYIGNDMIQPGMLAVV
                     EQYQAGLDWVPTSMTAYLAGGMFLQWLLGPLSDRIGRRPVMLAGVVWFIVTCLATLLA
                     KNIEQFTFLRFLQGISLCFIGAVGYAAIQESFEEAVCIKITALMANVALIAPLLGPLV
                     GAAWVHVLPWEGMFILFAALAAIAFFGLQRAMPETATRRGETLSFKALGRDYRLVIKN
                     RRFVAGALALGFVSLPLLAWIAQSPIIIISGEQLSSYEYGLLQVPVFGALIAGNLVLA
                     RLTSRRTVRSLIVMGGWPIVAGLIIAAAATVVSSHAYLWMTAGLSVYAFGIGLANAGL
                     VRLTLFSSDMSKGTVSAAMGMLQMLIFTVGIEVSKHAWLSGGNGLFSLFNLANGILWL
                     LLMLVFLKDKRTGNLQTV"
     gene            complement(14686..15501)
                     /locus_tag="OPV72_001109"
     CDS             complement(14686..15501)
                     /locus_tag="OPV72_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HCR9913473.1"
                     /translation="MSIKLIAVDMDGTFLSDQKTYNRDRFMAQYQQMKRQGIRFVVAS
                     GNQYYQLISFFPEIAHEIAFVAENGGWVVSEGEDVFNGELAKADFQAVVEHLLTRADV
                     EIIACGKNSAYTLKRYDDALKAVAAMYYHRLEFVDNFNNISDVFFKFGLNITDERIPE
                     VQAALHDAIGDIMVPVHTGYGSIDLIIPGVHKANGLRLLQQRWGIHDSEVVVFGDGGN
                     DIEMLRQAGFSFAMSHASEAVAAAAKYRAGSNNQEGVLDIIDSVLNNEPPFNV"
     gene            complement(15498..16709)
                     /locus_tag="OPV72_001110"
     CDS             complement(15498..16709)
                     /locus_tag="OPV72_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR9913474.1"
                     /translation="MTVLSSRNALKRRTWALFMFFFLPGLLMASWATRTPAIRDILSV
                     STAEMGTVLFGLSIGSMSGILCSAWLVKRFGTRKVIHTTMTCAVTGMVILSVALWCAS
                     PLIFALGLAVFGASFGAAEVAINVEGAAVERELNKTVLPMMHGFYSFGTLAGAGVGMA
                     LTALSVPANIHIILAAAVAIAPIFIAIRAIPDGTGKNASEGSHLQEKGLPFYRDIQLL
                     LIGVVVLAMAFAEGSANDWLPLLMVDGHGFSPTSGSLIYAGFTLGMTVGRFTGGWFID
                     RYSRVTVVRASALMGALGIGLIIFVDSDWVAGVSVILWGLGASLGFPLTISAASDTGP
                     DAPTRVSVVATTGYLAFLVGPPLLGYLGEHYGLRSAMMVVLALVILAALVAKAVAKPV
                     STPQPVMEHNA"
     gene            16877..17497
                     /locus_tag="OPV72_001111"
     CDS             16877..17497
                     /locus_tag="OPV72_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCR9913475.1"
                     /translation="MKENAVRRANDPKRREKIIQATLEAVKTYGVHAVTHRKIAAIAQ
                     VPLGSMTYYFAGMDALLSEAFTLFTENMSRQYQDFFAQVTDVEGACQAITEMIYGSQV
                     TTPDNMALMYQLYAYASDKPALKIVMQNWMQRSQNTLAQWFDAQTARALDAFIEGMTL
                     HFVTDRTPLAREAILQMVKRIAGESMSCHSASGNKKPTNLEPKWRG"
     gene            complement(17614..19299)
                     /locus_tag="OPV72_001112"
     CDS             complement(17614..19299)
                     /locus_tag="OPV72_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate:alanine antiporter"
                     /protein_id="HCR9913476.1"
                     /translation="MNINVADLLNGNYILLLFVVLALGLCLGKLRLGSVQLGNSIGVL
                     VVSLLLGQQHFSINTDALNLGFMLFIFCVGVEAGPNFFSIFFRDGKNYLMLALVMVGS
                     ALLIALGLGKLFGWDIGLTAGMLAGSMTSTPVLVGAGDTLRHSGIASTQLSSALDNLS
                     LGYALTYLIGLVSLIVGARYLPKLQHQDLQTSAQQIARERGLDTDANRKVYLPVIRAY
                     RVGPELVAWTDGKNLRELGIYRQTGCYIERIRRNGILANPDGDAVLQMGDEIALVGYP
                     DAHARLDPSFRNGKEVFDRDLLDMRIVTEEIVVKNHNAVGRRLAQLKLTDHGCFLNRV
                     IRSQIEMPIDDNVVLNKGDVLQVSGDARRVKTIADRIGFISIHSQVTDLLAFCAFFII
                     GLMIGMITFQFRNFSFGIGNAAGLLFAGIMLGFLRANHPTFGYIPQGALNMVKEFGLM
                     VFMAGVGLSAGSGISNGLGAVGGQMLIAGLVVSLIPVVICFLFGAYVLRMNRALLFGA
                     MMGARTCAPAMEIISDTARSNIPALGYAGTYAIANVLLTLAGTLIVIIWPGLG"
     gene            19570..19947
                     /locus_tag="OPV72_001113"
     CDS             19570..19947
                     /locus_tag="OPV72_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane protein YbjM"
                     /protein_id="HCR9913477.1"
                     /translation="MKHKHGWASVVCCFVLFIVVCLSLTMHVQGAFRAAGHPEIGLLF
                     FTLLGAVASFCSHRREVIRPLIGAMLAAPFCLVLMRVVFMPTRSFWQELAWLFSAVFW
                     CALGALCYLFISSLFSHRRKKRR"
     gene            complement(19979..20242)
                     /locus_tag="OPV72_001114"
     CDS             complement(19979..20242)
                     /locus_tag="OPV72_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrxA family glutaredoxin"
                     /protein_id="HCR9913478.1"
                     /translation="MFTVIFGRPGCPYCVRAKELAEKLSKERDDFNYRYIDIHAEGIT
                     KADLEKTVGKPVETVPQIFVDQKHIGGCTDFEAWAKENLNLFA"
     gene            20412..20702
                     /locus_tag="OPV72_001115"
     CDS             20412..20702
                     /locus_tag="OPV72_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbjC family protein"
                     /protein_id="HCR9913479.1"
                     /translation="MRTIGVLPKSVLILECLGMILLALALLSLNHYLTLPAPFNTSLA
                     GVLMVFLGVVLILPAAVAMMWRIAQLLAPQLMKRPPDISSRSDREKHNESDH"
     gene            20686..21408
                     /gene="nfsA"
                     /locus_tag="OPV72_001116"
     CDS             20686..21408
                     /gene="nfsA"
                     /locus_tag="OPV72_001116"
                     /EC_number="1.5.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase NfsA"
                     /protein_id="HCR9913480.1"
                     /translation="MSPTIELLCGHRSIRHFTDEPVTDAQREAIIAAARSTSSSSFLQ
                     CSSIIRITDRALREALVPLTGGQKHVAQAAEFWVFCADFNRHLQICPDAQLGLAEQLL
                     LGVVDTAMMGQNALTAAESLGLGGVYISGIRNNIESVTELLKLPKHVLPLFGLCLGWP
                     ADNPDLKPRLPAELVVHENQYQPLDEKLLARYDEQLAEYYLTRGSNTRRDTWSDHIRR
                     TLIKENRPFILEYLHKQGWATR"
     gene            21466..22368
                     /gene="rimK"
                     /locus_tag="OPV72_001117"
     CDS             21466..22368
                     /gene="rimK"
                     /locus_tag="OPV72_001117"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6--L-glutamate ligase"
                     /protein_id="HCR9913481.1"
                     /translation="MKIAILSRDGTLYSCKRLREAAMRRGHLVEILDPLSCYMNINPA
                     ASSIHYKGRRLPHFDAVIPRIGSAITFYGTAALRQFELLGSYPLNESVAITRARDKLR
                     SLQLLARQGIDLPITGIAHSPDDTSDLIKMVGGAPLVVKLVEGTQGIGVVLAETRQAA
                     ESVIDAFRGLNAHILVQEYIAEAKGCDIRCLVVGNEVVAAIERCAKAGDFRSNLHRGG
                     VASIATITPRERDIAIKAAQTLGLDVAGVDILRAARGPLVMEVNASPGLEGIEKTTGV
                     DIAGRMIQWIERHATPEFCLKIGG"
     gene            22465..22941
                     /locus_tag="OPV72_001118"
     CDS             22465..22941
                     /locus_tag="OPV72_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbjN domain-containing protein"
                     /protein_id="HCR9913482.1"
                     /translation="MISLVVPTLDTLRQWLDDLGMNFFECDTCQALHLPHMQNFDGVY
                     DAKINLVDNTVLFSAMAEVRPSALLPLAADLSAINASSLTVKAFLDMQDDNLPKLVVC
                     QSLSVMQGVTYEQFEWFVRQSEEQISMVILEAGAHQLLFNAEEDAQKTSAVDHFLH"
     gene            23290..24402
                     /gene="potF"
                     /locus_tag="OPV72_001119"
     CDS             23290..24402
                     /gene="potF"
                     /locus_tag="OPV72_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein PotF"
                     /protein_id="HCR9913483.1"
                     /translation="MTALKKKWLSGLVAGALMVVSVGTLAAEQKTLHIYNWSDYIAPD
                     TVANFEKETGINVIYDVFDSNEVLEGKLMAGSTGFDLVVPSASFLERQLTAGVFQPLD
                     KSKLPGWKNLDPELLKLVAKHDPDNKYAMPYMWATTGIGYNVDKVKAVLGDDAPVNSW
                     DLVLKPENLEKLKSCGVSFLDAPEEIFATVLNYLGKDPNSSKADDYTGPATDLLLKLR
                     PNIRYFHSSQYINDLANGDTCVAIGWAGDVWQAANRAKEAKNGVNISFSIPKEGVMAF
                     FDVFAMPADAKNKDEAYQFLNYLLRLDVIAHISDHVFYANANKEATALVSQQVRDNPG
                     IYPPADVRAKLFTLKVQEPKIDRVRTRAWTKVKSGK"
     gene            24490..25623
                     /gene="potG"
                     /locus_tag="OPV72_001120"
     CDS             24490..25623
                     /gene="potG"
                     /locus_tag="OPV72_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine ABC transporter ATP-binding subunit
                     PotG"
                     /protein_id="HCR9913484.1"
                     /translation="MNDAPHRPQVKTRKALTPLLEIRNLTKSFDGQHAVDDVSLTIYK
                     GEIFALLGASGCGKSTLLRMLAGFEPPSSGQIMLDGVDLAHVPPYQRPINMMFQSYAL
                     FPHMTVEQNIAFGLKQDKLPKAEITSRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVAL
                     ARSLAKRLKLLLLDEPMGALDKKLRDRMQLEVVDILERVGVTCVMVTHDQEEAMTMAG
                     RIAIMNRGKFVQIGEPEEIYEHPTTRYSAEFIGSVNVFEGLLKAREEDGLVIDAPGLV
                     HPLKVDADASVVDNVPVYVALRPEKIMLCESPPADGYNFAVGEVAHIAYLGDLSIYHV
                     RLKSGQMISAQLQNAHRYRKGLPTWGDEVRLCWEADSCVVLTV"
     gene            25633..26586
                     /gene="potH"
                     /locus_tag="OPV72_001121"
     CDS             25633..26586
                     /gene="potH"
                     /locus_tag="OPV72_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine ABC transporter permease PotH"
                     /protein_id="HCR9913485.1"
                     /translation="MSTLEPPARISKPGGAALWLARMQMKHGRKLVIALPYIWLILLF
                     LLPFLIVFKISLAEMARAIPPYTDLLEWADGQLSITLNLGNFLQLTDDPLYFEACLQS
                     LQIAGISTICCLLLGYPLAWAVAHSKPSTRNILLLLVILPSWTSFLIRVYAWMGILKN
                     NGVLNNVLLWLGVIDQPLTILHTNLAVYIGIVYAYLLFMVLPIYTALTRIDYSLVEAS
                     LDLGARPMKTFFSIIVPLTKGGIIAGSMLVFIPAVGEFVIPELLGGPDSIMIGRVLWQ
                     EFFNNRDWPVASAVAIIMLLLLIVPIMWFHKHQQKSVGEHG"
     gene            26583..27428
                     /gene="potI"
                     /locus_tag="OPV72_001122"
     CDS             26583..27428
                     /gene="potI"
                     /locus_tag="OPV72_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine ABC transporter permease PotI"
                     /protein_id="HCR9913486.1"
                     /translation="MNNLPVVRSPWRILILVLGFTFLYAPMLMLVIYSFNSSKLVTVW
                     AGWSTRWYGELFRDTAMMSAVGLSLTIAACAATMAVVLGTIAAVVMVRFGRFRGANGF
                     AFMITAPLVMPDVITGLSLLLLFVALGHTIGWPSDRGMLTIWLAHVTFCTAYVAVVIA
                     SRLRELDRSIEEAAMDLGAAPLKVFFVITLPMIMPAVISGWLLAFTLSLDDLVIASFV
                     SGPGATTLPMLVFSSVRMGVNPEINALATLILGVVGIIGFIAWYLMARAEKQRIRDIQ
                     RARRG"
     gene            27502..27975
                     /locus_tag="OPV72_001123"
     CDS             27502..27975
                     /locus_tag="OPV72_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbjO family protein"
                     /protein_id="HCR9913487.1"
                     /translation="MGFIKQSTSSHARLNVPTLVQVAAMAIILIRGLDVLMIMNTLGI
                     RGMGEFIHRSVQTWSLTLVFLASLVLVFIEIYCAFSLVKGRSWARWVYLAAQIIVSGY
                     LWAASLGYGYPELFSIAGESKRDILHSLVMQKLPDLLILFLLFIPAPSRRFFRLQ"
     gene            28018..29145
                     /gene="rlmC"
                     /locus_tag="OPV72_001124"
                     /pseudo
     CDS             28018..29145
                     /gene="rlmC"
                     /locus_tag="OPV72_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308966.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(747)-C(5))-methyltransferase
                     RlmC"
BASE COUNT         6504 a         7388 c         8260 g         7010 t
ORIGIN      
        1 cggcggcgca ggcgcgattg ctcgcgcgca aatgagccat gagcaggagc tacgctatat
       61 ccaggcgctg tcagagattg tcgaaagcgg gcaaaagatg ctggaagcgg gtgacagcgc
      121 gcttgatgta gtgacggaag cggtgcgcct gctggaagcg tgtccgctct tcaatgcggg
      181 tatcggcgcg gtctataccc gagacggaac tcatgaactg gatgcctgcg tgatggacgg
      241 caataccctg aaagccggag ccgtcgcggg cgtgagtcat gttcgccatc ctgtgctcgc
      301 cgccagactg gtgatggagc gcagcccgca tgtactcatg gtgggggaag gggcggaaaa
      361 ctttgccttt tcacagggga tggcgcgcgt ttcgccggat atcttttcca ccccggcgcg
      421 ttacgagcaa ttgctggcgg cgcgtgcggc gggcgaaatg gcgctcgatc acagcggcgc
      481 gccgctggac gaaacgaaaa aaatgggtac agtcggcgcg gtggcgcggg ataaattcgg
      541 caatctggcg gcggcaacgt ctaccggcgg gatgaccaat aaattgcccg ggcgcgtcgg
      601 cgacagcccg ctggtcggcg ccgggtgtta tgccaacaac gccagcgtcg ccgtttcctg
      661 taccggaacg ggagaggtct ttattcgcac gctcgcggct tacgatatcg ccgcattgat
      721 ggaatatggc ggactcagcc ttgccgacgc ctgtgagcgc gtggtgatgg aaaaattacc
      781 ggcgctgggc ggcagcggtg gattaatcgc cgttgatcac gaaggtaatg tcgcgttgcc
      841 gtttaacagc gaagggatgt atcgcgcctg gggatatgcc ggggatacgc ctaccacagg
      901 aatttaccgg gaataaggag ccgcaggtgc cgcacagcga tgaactggat agccgcgatg
      961 ttctgtccgt cagtggcctg aatatcgcgt ttcaccacga agggcaacag gtagacgccg
     1021 tgcgtaatgt gtcattacgc ctgaagcgtg gagagactct gacgattgtc ggcgagtcgg
     1081 gctcgggaaa atcggtgacg gcgctggcgt taatgcggct gattgagcag tcgggcgcga
     1141 acgtgcgctg cggcgaaatg ctgttgcgtc ggcgtaatcg ccaggtgatt gagctgtctg
     1201 agcagagtga cgcgcagatg cggcgtgtgc gcggcgcgga tatcgccatg attttccagg
     1261 agccaatgac ctcgctcaac ccggtattta ccgttggcga gcaaattgcc gaatctattc
     1321 gtttgcatca gggggccagc cacgaagagg cgctggcgga agcgaaacgt atgctcgatc
     1381 aggtacggat cccggagtcg caggcgattt tatcgcgtta tccgcatcag ctttccggcg
     1441 ggatgcgcca gcgagtcatg attgcgatgg cgctatcctg ccgtccggcg gtattgattg
     1501 ccgatgaacc caccacggcg ctggatgtca ctatccaggc gcaaattctg caacttatca
     1561 aagtgttgca gcaagagatg tcgatgggcg tgatttttat cactcacgac atgggcgtcg
     1621 tggcggatat tgccgatcgc gtgctggtga tgtatcaggg cgaggccgtg gaaaccggca
     1681 gcgtagagca gattttccat gcgccgacgc atccttatac ccaaacgtta ctggccgccg
     1741 tccctcagct tggcgcgatg cgaggccact cgctgccacg ccgtttcccg ttgatttccg
     1801 ctgacgaacc ggccctttat gaatcgcaga ttgagcaaga cacggtggtg gaaggcgaac
     1861 ctattctcca ggttcggggg ctggtgacgc gattcccgct gcgtagcggt ctctttaacc
     1921 gcgttacgcg tgaagttcat gccgttgaga atatcagttt cgatctctgg cccggcgaaa
     1981 cgctatcgct ggtgggcgag tccggtagcg gaaaatcgac gaccggacgc gcgctgctgc
     2041 ggttggttga atcccggcag ggggagatta tctttaacgg ccagcgcatt gacacgctgt
     2101 ctgcgggtaa actccagccg ttgcgccgcg atattcagtg tattttccag gacccttacg
     2161 cctcgctcga cccgcgccag accgtggggt attccattat ggaaccttta cggattcatg
     2221 gtctggggca gggggacgct gcggcaaagc gcgtggcctg gttgcttgag cgtgtcggat
     2281 tacgtcctga acatgcctgg cgttatccgc acgagttttc cggcggtcaa cgtcagcgca
     2341 tctgcattgc tcgcgcgctg gcattgaatc ctaaagtgat tattgctgat gaggcggtct
     2401 ccgcgctgga tgtttccgtt cgcggacaga tcattaattt actgctcgat ttacaacggg
     2461 aaatggggat cgcctacctg tttatttcgc atgatatggc ggtcgtggag cgaattagcc
     2521 atcgcgtggc ggtgatgtat cttggtcaaa ttgttgagat ggggccgcgg cgcgccgttt
     2581 ttgaaaatcc gcagcatcct tatacgcgta aattgatggc ggcggtgccg gttgccgatc
     2641 cctccagaca ccggccgcgg cgcgttctgc tatcagatga tatacccagc aatattcata
     2701 aacgtggcga agagacgccc gccgtttcat tacagttggt cgggccggga cattatgttg
     2761 cgcggccgct gcaggataat gcgctctcgc gcttataaca ttcagacagg cagggtttca
     2821 ggagaacaac atgacgcaat ttattacgca taaatggctg gcggcgctgg gactggcctc
     2881 atccattgcg gcttttccgg ccctggcggc caaagatgtg gtggtggcgg tagggtctaa
     2941 tttcaccacg ctcgatccgt atgacgccaa cgatacgctc tcgcaggcgg tggcgaagtc
     3001 attttatcaa ggtctgtttg gcctggataa agacatgaag gtaaaaaacg tcctggcgga
     3061 aggctatacc gtttctgatg acggtctgac ctacaccatt accctacggc agggggtgaa
     3121 atttcaggac ggcgcggatt ttaatgcggc ggcggtaaaa gcgaatctcg atcgcgccag
     3181 caatccggat aaccacctca agcgttataa cctgtataaa aatatcgcaa aaacggaggt
     3241 cgtcgatccg gcaacggtaa aaattaccct gaaacagccg ttctccgctt tcattaatat
     3301 tctggcgcac ccggcgacgg cgatgatctc gccgcaagcg ctggaaaaat atggcaagga
     3361 tattggtttt catccggtcg gcactggtcc atatcagctt gaaacctgga atcagaccga
     3421 ctttgtcaaa gtgaaaaagt tcgccggtta ctggcagcag ggcttaccca agctggattc
     3481 tattacctgg cgtccggtta ctgacaacaa tacccgcgcg gcgatgctgc aaaccggcga
     3541 agcgcaattt gcttttccta tcccttatga gcaggccgcg ttactggcga aaaataaaaa
     3601 cctcgaactg gtcgccagcc cgtccattat gcagcgttat atcagtatga atgtgacgca
     3661 gaagccgttt gataatccta aggtgcgtga ggcgttgaat tacgctatca atcgtcaggc
     3721 gctggttaaa gtggcgtttg ccggatacgc cacgccggcg acgggcgtgg tgccgccgtc
     3781 gatagcctat gcgcaaagct atcagccgtg gccctatgat ccggctaaag cgcgcgaact
     3841 attgaaagag gcggggtatc cagacggttt cagtaccacg ctgtggtcat cgcacaacca
     3901 tagcaccgcg caaaaagtgt tgcagtttac ccaacagcaa ctggcgcaga ttggcattaa
     3961 agcccggata accgcgatgg acgccggcca gcgcgccgcg gaagttgagg gcaaagggca
     4021 aaaagagagc ggcgtgcgaa tgttctatac cggctggtcg gcgtcgacgg gcgaagctga
     4081 ctgggcgtta tcgccgctct tcgcatcaca aaactggccg ccgacgcagt ttaataccgc
     4141 tttttacagc aacaagcagg tcgacagcga tttggcggcg gccttaaaga ctaacgatcc
     4201 gcaggagaaa acacgattat acaaagaggc gcaggatatt atctggaaag agtcgccctg
     4261 gataccgttg gtggtggaga aattggtttc tgcgcacagt aaaaatttga ccggtttctg
     4321 gattatgccg gataccggtt tcagctttga cgatgcggat ttgaagtaag taatgcgatg
     4381 gggctggatg gcgcgcgcgt tgtccgccat ccggtaaaag gttcgtgtga tgcttaacta
     4441 tgttctcaag cgcctgctgg gattaattcc tacgctgttg attgtggcag tgctggtgtt
     4501 tttatttgtt catttgttgc ccggcgaccc ggcgcggctg atagccggac cggaagccga
     4561 cgcgcaggtg atagcgctgg ttcgtcagca gctggggctt gatcagccgc ttcatgtcca
     4621 gttttggcat tacatcaccc atgttttaca aggcgatttc gggacgtcaa tggtttcccg
     4681 ccgcccggtt tctgaggaga tcgccagccg ctttttgccg acgctgtggc tgacgataac
     4741 cagtatgata tgggcggtgt tgtttggcat ggcgatcggc atcgccgccg ccgtgtggcg
     4801 taatcgctgg cctgaccggg taggaatgac gcttgccgtg accggcattt ctttcccggc
     4861 ttttgcgctg ggaatgttgt taatgcagat tttttccgtg gatctgggct ggctaccgac
     4921 cgtgggggcg gatagctggc aacattatat tttaccctcc ctgacgcttg gcgcggcggt
     4981 ggcatcagtc atggcgcgtt ttacgcgctc ctcgtttgtc gatgtgctga gcgaggatta
     5041 catgaggacc gcgcgggcga aaggcgtcag tgaaacgtgg gtggtgttaa aacatggcct
     5101 gcgcaatgca atgatcccgg tcgtcaccat gatgggactg caatttggct ttctgcttgg
     5161 cggatcgatc gtcgtcgaaa aagtgtttaa ctggccgggg cttgggcgat tactggtcga
     5221 ctccgtcgac atgcgcgact accccgtgat tcaggcagaa gtgctgctgt tttctctgga
     5281 atttattctt atcaacttag tggtggatgt cctctatgcc gccattaatc cggctatcag
     5341 gtataagtaa ggatgcgatt atttaactgg cgccgtcagg cgattttaca tgctatgccg
     5401 gtggtaaaac ccgaccagat acgcacgccg tggcgggagt tctggcgtcg ttttcgccgc
     5461 cagcatgtcg cgttggtcgc cgggggattc gtactggcgt taattctggt ggcgattttt
     5521 gcccgttggc taacgcccta cgatgcggaa aactattttg actacgatag cctgaacaat
     5581 ggcccctctt tgcagcattg gtttggcgtt gactcgctgg gaagagacat ctttagccgg
     5641 gttctcgttg gcgcgcagat ctcactggcg gcgggcgtgt tcgcggtatt tatcggcgcg
     5701 ataatcggca cggtgttggg attgctggcg ggatattatg aaggctggtg ggatcgtttc
     5761 attatgcgca tttgcgatgt gttgttcgcc ttccccggca ttttgctggc gattgccgtt
     5821 gtggcggtgt taggcagcgg tattgctaat gtgatcgttg cggtggcgat tttctctatt
     5881 ccggcgtttg ctcgtctggt gcgcggaaat accctggtct taaaacagca gacgtttatt
     5941 gagtctgccc gcagtatcgg cgccagcgac acgacgattt tgtttagcca catcttgccg
     6001 ggaacggtct cgtcaattgt ggttttcttt acgatgcgta tcggtacgtc aattatttcc
     6061 gcggcaagcc tgtcatttct cgggttaggc gcgcagccgc caacgccgga gtggggagcg
     6121 atgcttaatg aagcgcgggc ggatatggtc atcgcgccgc acgtggcgct cttcccggcg
     6181 gtggcgattt tcctgactgt gctggcgttt aatctgttag gcgacgggtt gcgcgatgcg
     6241 ctggacccga agattaaggg gtaagccagc ccggtggcgt tgacgcctgg cgggcctgga
     6301 accggctcgc caggtggggt aacacattcg gcacccgcgc cgggggaagt ggcgttaaac
     6361 ccgactgccc cacaaatcat attcgtcggc gttttccact ttcacgcgca cgatatcgcc
     6421 cggcttgacg ttggtttcgc cgttcaaata gaccgcgccg tcaatttccg gcgcatccgc
     6481 catgctacgc ccgatagcgc cttcttcgtc aacctcatcg acgatcacca gaatttcgcg
     6541 gcccactttt tcctgcaagc gctcagcgga gatttgctgt tgcagttgca taaagcggtt
     6601 ccagcgctct tctttcacct cttccggcac ctgatccggc agctcattcg cgcctgcgcc
     6661 ttccaccggg ctgtacttga agcagcctac acgatcgagg cgcgcctctt tcaggaagtc
     6721 gagcagcatc tggaagtctt cttccgtttc gccggggaag ccgacaataa aggtggagcg
     6781 tagggtcagt tccgggcaga tttcgcgcca ctgcttaatg cgcgccagct ggcggtcaac
     6841 ggaaccagga cgtttcatca gtttaagaat ccgcgggctg gcatgttgca gcggaatgtc
     6901 cagataaggc aggattttgc cttccgccat tagcggaatc acatcatcaa cgtgtgggta
     6961 ggggtagacg tagtgcagac gtgtccagac gcccagtttt gataactgct cgcacaggct
     7021 caccatactg gttttcatcg gttcgccatt atggaatccg gtgcggtgct tcacatctac
     7081 gccgtaggcg gaggtatctt gcgaaatcac cagaatctct ttgaccccgg catcaaccag
     7141 acgtttcgct tcgcttaata cgtcgccaat cggacggctg accagatccc cgcgcatcga
     7201 cgggatgatg cagaacgtgc agcggtgatt acagccttca gaaattttca gatacgcata
     7261 atggcgcggc gtcagtttta caccctgttc cggtacgagg cttaaaaatg gattgtgctt
     7321 cggcttcggt acgtaatgat gtacgtgctg cagaacttgc tcatagctat gcggcccggt
     7381 gatttccagt actttcggat gcacttcgcg gatctgatct tcttttgcgc ccaggcagcc
     7441 ggtgacgatt accttaccgt tttcgttcag cgcttcgcca atggcttcca gtgactcttg
     7501 taccgcgctg tcaataaagc cacaggtatt aacgataacc atatccgcat cgtcatagtg
     7561 tggcacaacg tcatagcctt cggtacgcag ctcagtcagg attcgttccg aatcaacgag
     7621 gtttttcgga cagcccaggg aaacgaagcc gatctttggc tggtgggtta cattactcat
     7681 agcttaaaaa gtgttcattt attggaatgg tcagggcagg gattctacag atatccgaac
     7741 aaaaattgta tcgcaatctc atcaggagcg gcggcatcaa ccgttgtggt tatcagcaaa
     7801 aggtgaaaaa gggcaattct aagaaaattc ttgatctctg acaccccttt gtctaaaaaa
     7861 cgaccatact attaagttga accctggtag aaaagaggag gaaaaaaggt atggtcgttg
     7921 acagactgag aaccgatctt ctcaacaagc tgataaacgc gcgtatcgat cttgccgctt
     7981 atctgcaatt gcgaaaagcg aaggggtata tgtcagtcag cgaaagtgac actctgcgtg
     8041 acaatttttt tgaactgaat cgcgagctcc acgatcacgc tttacggcag ggactgcatc
     8101 tcgatcagga agagtggaac gcgctgcgcc gtgccgaagg cgcgcttgca gccgccgccg
     8161 tttgtttaat gagtggacac catgattgtc cgacctttat tgccgtcaac gcagataaac
     8221 ttgaaaactg tctgacaact ttgacgctga gtattcagag tctgaaagca cattcaccgc
     8281 ttacacaggt ctgaataagg gggaggcgac tccccctttt taccggaccg cgccgcttaa
     8341 tgttttgtaa aaataaaccc gacctcttgc gatgctgact acgctttaac gcagagccct
     8401 gaaggaggcg gtatgcgtcg aatacttctc gcgatagttt cattctctct tttctcttca
     8461 tgggcgaacg ccaatcttgc gccggtgaac gttgaggtgc tgcaaacccg actcgatcac
     8521 ccgtggtcgc tggctttttt gccggataac cgtgggatgc tcattaccct gaaaggggga
     8581 caactgcgcc actggcagac ggggcgggga ctttccgatc cgctggctgg cgtaccgaaa
     8641 gtgtgggcaa acgggcaggg aggtttgctg gacgtcgtgc tggcgcctga ttttgcccag
     8701 tcgcgccgcg tctggctgag ctatgctgaa gctgaccgcg aaggaaacgc cggtacggca
     8761 gccggctttg gacggctgag cgacgatttt cagcgtctgg agcattttcg taccgtgttt
     8821 cgccagatgc ctaagctgtc taccggcaac catttcggcg gacgtatggt attcgatgcg
     8881 caagggtttc tttttattgc cctgggtgaa aataaccagc gcgctaccgc gcaggatttg
     8941 gataaattac agggtaagct ggtgcgcctg accgggcagg gcgaaattcc gccggataat
     9001 ccgtttgtac atcaggcggg cgcgcgtccg gaaatctggt cttacggtat tcgtaatccg
     9061 caggggctgg ccatcaatcc ctggagcggc gcgctatggc tgcatgaaca cggtccgcgc
     9121 ggcggcgatg aaattaacat cccggaaaaa ggcaaaaatt atggctggcc gctggccaca
     9181 tggggcgtca actatagtgg tctgaaagtg ccggaagcca aaggtgaaat tgtcgaggga
     9241 acggagcaac cggtttacta ctggaaggat tctccggcga tcagcgggat ggctttttat
     9301 gccagcgacg tttttgcgcc gtggcggcac aaactgttta tcggcgcgct aaaagataaa
     9361 gaggtcattg tgatgcgcgt cgatggcaat acggtgacgg aagaaggccg tattctgggt
     9421 gacagaaagc agcgtattcg ggatgtgcgt gtcggacctg acggctactt atatgtgtta
     9481 accgatgagt ccgacgggca gttactcaag gtaagtcctg cagccacgcg ttaggtcacc
     9541 gggatcatca ccactttgcg aaaagcaggg cgctcggtaa gctgttgata ccagcgttgc
     9601 agattcgggc gcggcgtcca cttcagaccc acgttcagca ggttatagac gaagggcgca
     9661 atagcgatat cgccggtgcc aaagttatcc cctgagaacc acggctggtg ggccagcgca
     9721 tcatcaagaa gcgcaaacag gctatcacac ttttcgatac cggcttcaat tgccgcctgg
     9781 tcgcgttttt ccggcggggt tctgaccagt cccatcagga tcacgcggtg cgccgggctt
     9841 aacgtttgat tcgcccagtc catccatttt tcgccctccg cacgccgtgc cggattatca
     9901 acccatagcc ggttctggcc gtattgcgcc gccagatagc ggacaatggc attggattcc
     9961 cacaataaca ggtcggtttc atcatcttta agcagcggca ccagcccatt aggattcatc
    10021 gccagatagt cggcatcctg gttaacgccg aattttccac ctgccagaat ttgatcgtat
    10081 ggcagttcca gctcttcaag cgtccacaac acttttttaa cattagtcga gttgttccgg
    10141 ccccacagcg taatcatatt aaccccttct gttttatcag gatgatgaca gtaatcggcc
    10201 taccgtgaga taaacctaac atttacacaa tggtctgtaa aaaaatcgtt atgaaggaag
    10261 cgtaacggga tgttattgca taaactttaa aaactttacc aagttacggt ttctttaacg
    10321 tcgtgagtgc gttattactc accgcactta ttacacggtg gtgtgacgtg tgtttttgga
    10381 atggatactc gggtggtact atgacgcaat acgcttcttc ccttcgtagc ctcgcggcag
    10441 gttcggttct cttattcctt ttcgcttcgc ctgtaaaggc agaggaacaa acgatcgcgc
    10501 cgccgggcgt tgatgcgcga gcctggatct taatggatta cgccagcggt aaagtactgg
    10561 cggaaggcaa cgccgatgag aaactcgacc ctgccagttt gacaaaaatt atgaccagct
    10621 acgtggtggg ccaggcgctg aaggcaggca aaatcaagct gaccgatatg gtgacggtgg
    10681 gcaaagatgc ctgggcgacg gggaacccgg cgctacgtgg gtcgtcggtg atgtttctga
    10741 agcccggcga tcaggtgtcg gttgcggatc ttaataaagg catcatcatt cagtcaggta
    10801 atgatgcctg tatcgcgctt gccgactacg tcgccggaag ccaggagtcc tttatcggcc
    10861 tgatgaatgc ctatgcgaaa cgattggggt taaccaatac aaccttccag acggtacacg
    10921 gccttgatgc gccagggcag ttcagtaccg ctcgcgatat ggcgctgctc ggcaaggcct
    10981 tgattcacga tgtgcctgac gaatacgcca ttcataaaga gaaagaattt acttttaata
    11041 atattcgtca gccaaaccgc aaccgcctgt tgtggagtac caatctgcat gtcgacggca
    11101 tgaaaacggg gacaacggca ggcgctggat ataaccttgt cgcctccgcc acccagggcg
    11161 atatgcgcct gatctctgtc gtgctggggg cgaaaacgga ccgtattcgt tttaatgagt
    11221 cagaaaaact gctgacctgg ggtttccgct tctttgaaac ggtcacgccg attaaacctg
    11281 acgcgacatt cgtgacgcaa cgggtctggt ttggcgataa gcgtgaggtc aatttgggag
    11341 cgggcgatgc ggggtctgtg acgattccgc gtgggcagct taaaaacctg aaggccagct
    11401 ttacgttgaa cgaaccacag ctcacggcgc cattgaagaa agggcaggtt gtcggcacca
    11461 tcgatttcca gcttaacgga aaatccattg agcaacgccc gttaatggtg atggaaaacg
    11521 tcgaggaggg gggatttttc agccgtatgt gggattttgt gctgatgaaa ctccatcagt
    11581 ggtttggcag ttggttctcg taaaataacc ccgttgccgg gtgcgcgtcg catccggcaa
    11641 acctgcggtt aatacatcag agtaatttgt tgcgctttag cgtaggccac aaaggcctca
    11701 tcgggacggc ggtcgctgat aatcgtatca aagcgtgata attcccccat ccgcgccgga
    11761 cgtaccttgc cgaatttact gtgatccacc accagtacat ggctctgggc cattgtcatg
    11821 gcccaatgtt ttaccggcag ctcttccaga ttaaagcagg tagcgccttt actggtatga
    11881 acgccggcgg cggaataaaa cgcgatatcc ggacaaatat tgtttaacgt ttcatggaaa
    11941 tcaagcggtt tgaaaatggc gttgctggcg tgaaactccc cgccgctgag gatggcgcgg
    12001 caatggggtt tgtcctgcag cgccagaaag gtattaagtg aatagcacac cgccgtaaag
    12061 ggaagatcat tatcaatagc ttcaatgatc cacggcgtgg tggtgccgca gtcaataaat
    12121 accgtctgat gcgcttgtac caagcccgca gccaactgag cggcacggcg tttttcttcc
    12181 accagacgag atttttgatc gcttaacaga taatgactgg cgctgcgggg ctccagtacg
    12241 atatagccgc ccagcaacac gacaggcgcg cttttatggt tcaggtcgcg acgaatggtc
    12301 atttcagaga cgcccaacag ggtcgcggct tctttaagat gaagtttatc gctgcgtttt
    12361 aaggcctgca gcaattgacc aatacgctcg tcgcgtcgcg tttccatagt tcccctggag
    12421 agttaaataa gcgctccgca ccatacagag cgcttaatat tactcttttt ttcgctattt
    12481 agtcacgtac ccagcctttt cgaatgggca atgcgaaaca gaaacggtaa caacgttgca
    12541 gcgcctggta gagcggcgcg ccgtaccatt gccagatcag ctgtgcgctc aggcagccaa
    12601 gcatcgctac cagcagcgcg ccaatcatat ctaacggcca gtgtacgccg agatagacgc
    12661 gcgaccaggc gatggtcatg gctatcgcca tcatcacgat gcctgaccag aggcggtgcc
    12721 agaacaaaaa cgccagcgca aaggtaaaaa tcaccgtacc gtgatcgctg gggaacgagt
    12781 catcggcggc atgatgcagg aagttatagc cgatatgatc gacaaacgga cggtcgtgcg
    12841 ggaaaaggtg tcccattgtc caggagaccg ccagactgat aatcagcgcg atgccgattt
    12901 taacgatcag ctggcgctgg gcgcagaccc gatcgcgggg cccccacagc cagagtacca
    12961 cggctaagag cgggacgatg ttgatgacat ctttggcgat aaagatagcg agcgaaatta
    13021 tccactgcgc ggaatcaggc gtggcgttaa taaaataaaa cagcgagttg ttaaggtttt
    13081 ccagcataac atccaggctc ggagcaatga aatcaaaagg gatagccagc tcatccccgt
    13141 gcaaactgag cataaatgca gcgtaacagg gaggaaaagc agtattgtct tatttggcgg
    13201 caacatgaag agatttaaga caatggcata aaataacgtt gatgataacg gcgcaaactt
    13261 aaattaacct taaagtacgc aagcgctaag cagctttctg taaaaatgtg cgctatttcc
    13321 cttgcagcct cataattcgc tatctcagtt ccccgacttt cattacactc tgcgcggttt
    13381 ttattggcga agagatggta tgcagaatcg tttacaatca ggcggcaggc tgggacgtca
    13441 ggcgctgctt tttcctctct gtctggtgct gtacgagttt tctacttata ttggcaacga
    13501 catgatccaa ccgggtatgc tggcggtggt tgagcagtat caggcgggcc tggactgggt
    13561 tccgacgtcc atgaccgctt atctggcggg cggtatgttc ttacaatggc tgcttggccc
    13621 gttgtctgac cggattggcc gtcgtcccgt gatgctggcg ggcgtcgtgt ggtttattgt
    13681 cacctgcctg gcgacgttac tggcgaaaaa catcgaacaa tttacattcc tgcgtttttt
    13741 gcaagggatt agcctgtgtt ttatcggcgc tgtagggtat gccgcgattc aggaatcctt
    13801 tgaggaggcg gtgtgtataa aaattaccgc gctgatggcg aacgtggcgt taatcgcgcc
    13861 gctactggga ccactagttg gggcggcatg ggtgcatgtt ctgccgtggg aggggatgtt
    13921 tattttattt gccgcactgg ccgctatcgc ctttttcggg ctacagcgcg caatgccgga
    13981 gaccgccacg cggcggggcg aaacgctgtc atttaaggcg cttggccggg attatcggct
    14041 ggtgataaaa aatcggcggt tcgtcgcagg ggcgttagcg ctgggatttg tcagcctgcc
    14101 gctgttggcc tggattgcgc agtcgccgat tatcatcatt agcggcgaac agctcagcag
    14161 ctatgaatat ggtttgctgc aggtgcccgt ttttggcgcg ctcattgccg gtaatctggt
    14221 gttggcgcgt ttaacctccc gacgtacggt tcgctcgctg atcgtgatgg gcggctggcc
    14281 tatcgtcgcg gggctgatca tcgccgcggc ggcgacggtg gtttcatccc atgcttattt
    14341 atggatgacg gcgggattaa gcgtatacgc ttttggcatt gggctggcga atgccggact
    14401 ggtgcgtctg acgctctttt ccagcgatat gagtaaagga acggtctcgg cggcgatggg
    14461 aatgctacaa atgctgattt ttaccgttgg cattgaagtc agtaaacacg cctggttaag
    14521 cggcggcaat gggctattta gcctgtttaa tctggcaaac ggtattcttt ggctactgct
    14581 gatgctggtc ttcttaaaag ataagcggac ggggaatttg caaacagtct gagagagcgg
    14641 ctacgcctga taagctttct gttatcaggc gtagagaggc atccgctaga cgttgaacgg
    14701 cggctcgttg tttaatacgc tgtcgatgat atccagcacg ccttcctgat tgttcgatcc
    14761 ggcgcggtat ttcgccgccg ccgcgaccgc ttcgctggcg tgcgacatgg caaaactaaa
    14821 cccggcctga cgcagcatct caatatcgtt gccgccgtcg ccgaatacca ccacttcact
    14881 atcatgaatg ccccagcgct gctgtaacag acgcaggccg ttggctttat gcacgccggg
    14941 aattattaaa tcaatactgc catagccggt atgaacgggg accatgatat cgccaatggc
    15001 gtcgtgcagc gccgcctgta cttccggtat ccgttcatcg gtaatattaa ggccgaattt
    15061 gaaaaaaaca tcgctgatat tgttgaaatt atccacaaac tccagacgat gataatacat
    15121 tgccgcaacg gcttttaacg catcgtcgta ccgtttcagc gtgtaggcgc tgttttttcc
    15181 acaggcgatg atctccacat cggcgcgtgt gagcaggtgt tcgacaaccg cctggaagtc
    15241 ggcttttgcc agctcgccgt taaaaacatc ctctccttcg ctgaccaccc agccaccgtt
    15301 ttccgcgaca aaagcgattt cgtgcgcaat ttccggaaag aaggagatta actggtaata
    15361 ctggttgccg ctggccacga caaagcgaat gccttgccgc ttcatttgtt ggtactgcgc
    15421 cataaaccgg tcacggttat aggttttttg atcgctcaga aaagtgccgt ccatgtcgac
    15481 ggcgattaat ttaatactca tgcgttatgc tccatcaccg gttgcggagt cgatacaggt
    15541 ttggcgacgg ccttcgccac cagcgctgcc agaataacca gcgccagcac aaccatcatg
    15601 gcgctgcgta atccatagtg ctctcccaga tagcccaaca gcggcggccc gaccaaaaac
    15661 gccagatagc cggtcgtggc gacaacgctc acgcgcgtcg gcgcgtcggg accggtatcg
    15721 ctggcggcgg aaatggtcag cgggaagccg agcgaagcgc ctaagcccca aagaatgacc
    15781 gagacgccgg caacccagtc gctatcgaca aaaataatca ggccaatgcc caacgctccc
    15841 atcaacgcgc tggcgcgaac aaccgtcacc cggctatagc ggtcaataaa ccagccgccg
    15901 gtaaagcggc caacggtcat accaagcgtg aaaccggcgt agatcagaga gccggaggtt
    15961 gggctaaaac cgtgtccgtc taccatcagt agcggtagcc agtcattcgc agatccttcg
    16021 gcgaatgcca ttgccagcac caccacgcca ataagcaaaa gctggatgtc ccgataaaaa
    16081 ggtaatcctt tttcctgaag gtgagaacct tccgatgcgt ttttacccgt accgtcaggg
    16141 atcgcccgaa tggcgataaa aatgggcgcg atcgccacgg cagccgcgag gatgatatgg
    16201 atgttagccg ggacgcttaa tgcggttaac gccatgccga caccagcgcc cgccagcgtg
    16261 ccgaaactgt agaaaccatg catcatcggc agaacggttt tattcagctc gcgttcgacc
    16321 gccgcgcctt cgacattaat cgccacttcg gcggcgccaa aactggcgcc gaaaacggct
    16381 aatccaaggg caaaaatcag cggcgaggcg caccacagcg cgacgctaag aataaccatc
    16441 ccggttactg cgcaggtcat cgtcgtgtga ataaccttcc gggtgccaaa tcgtttcacc
    16501 agccaggcgg aacaaagaat accgctcatt gaaccgatag aaagcccgaa taagaccgtc
    16561 cccatttccg cggtagagac ggaaagaata tcccgaatag caggcgttcg ggttgcccag
    16621 gaggccatca gcagtccggg taaaaagaag aacataaaca gcgcccaggt acggcgtttt
    16681 aaggcgttac gtgaggagag gacggtcata gcgtcaggcc agaaaataga agcgagaggt
    16741 aaacattagc aagcttgtgt acatttgtac atatcgtcgt catacttcgt tgtgcagaca
    16801 gtttttgctg tctgtttttt cagcgtaagc ggcaggctac tatcgcctgc atcctgaatg
    16861 agatgtggaa ctcatcatga aagaaaatgc cgtaagacgc gccaatgatc ctaagcgacg
    16921 ggaaaaaata attcaggcca cactggaagc ggtaaagacc tatggcgttc atgccgtgac
    16981 gcaccggaaa atcgccgcta tcgctcaggt gccgcttggc tcgatgacct actattttgc
    17041 cggtatggat gcgttattga gtgaagcttt tacacttttc accgagaaca tgtcgcgtca
    17101 ataccaggat ttttttgcgc aggtgacgga tgtggagggg gcgtgccagg cgataacgga
    17161 aatgatttac ggctcgcagg ttacgacgcc ggataatatg gcgttaatgt atcagttata
    17221 tgcctatgcc agcgataagc cagcgttaaa aatagtcatg caaaactgga tgcagcgtag
    17281 ccagaatacg ctggcgcagt ggtttgacgc acagaccgcc cgcgcgctgg atgcgtttat
    17341 cgaggggatg acgctgcatt ttgtgacgga tcgaacgccg ttggcgcgtg aagcgatttt
    17401 acagatggta aagcgaatag ccggagagtc aatgtcgtgt cactctgcgt cgggcaacaa
    17461 aaaacccacc aaccttgaac cgaaatggcg gggttgatgg gctccacaaa atggggacat
    17521 caaagaaaag cagtggcaat aggtatgact gatgctttaa cgaaaagttc gacctattgg
    17581 caaaattttt tcacttaaag gcaaacttca gttttatcct aatcccggcc agatgatgac
    17641 aataagcgtc cccgccagcg ttagcagaac gttggcgatg gcgtaagtcc ccgcataacc
    17701 cagcgctgga atattgctgc gcgctgtatc gctaatgatt tccatcgccg gggcgcaggt
    17761 acgcgcgccc atcatggcgc cgaacagcag cgcccggttc atgcgcagca cataagcgcc
    17821 aaacaagaag cagatcacca ccggtatcag gctgacgaca agcccggcga tcagcatttg
    17881 tccgccgacc gcgcccagac cgttgctgat accgctgccg gcgcttaaac caacgcctgc
    17941 cataaatacc atcaagccga attctttcac catgttaagc gcgccctgcg gaatataacc
    18001 aaaggtagga tggttagcgc gcaggaaacc gagcatgatc ccggcgaaca gcaatccggc
    18061 cgcgttgccg atgccgaaac taaaatttct gaactggaag gtaatcatcc cgatcattaa
    18121 cccgatgata aaaaaagcgc agaaggcgag caggtccgtc acctgactat ggatcgaaat
    18181 aaaaccaatg cgatcggcga tggtttttac gcgtctggcg tcgccgctca cctgtaacac
    18241 gtcgccttta ttcagcacga cgttatcgtc gataggcatt tcgatctggc tgcggatgac
    18301 gcggttaagg aagcagccat gatcggtcag cttgagctga gcgaggcggc gaccgaccgc
    18361 attgtggttt ttcaccacaa tttcctccgt cacgatgcgc atatcaagca gatcgcgatc
    18421 aaacacttcc ttaccattac ggaagctggg atcgagcctg gcgtgcgcgt ccggatagcc
    18481 gaccagcgca atctcatcgc ccatttgcag caccgcatcg ccatccgggt tcgccagaat
    18541 accgttacga cgaatacgtt cgatatagca gcctgtctgg cggtaaatac ccagctcgcg
    18601 caggttttta ccgtcagtcc aggccaccag ttccgggcca acccgatagg cgcggataac
    18661 cggcaaataa accttgcgat tagcatcggt atccagaccg cgctcgcgag caatttgctg
    18721 ggcgctggtt tgcaaatcct gatgctgtag tttaggcaag taacgcgcgc ccacgatcag
    18781 actgaccagc ccaatcagat aggtcagggc atagcccagg ctcagattat caagagcgga
    18841 ggagagttgg gtgctggcga tgccggaatg tcgcagggta tcgcctgcgc caaccagcac
    18901 gggcgtggat gtcattgagc cggccagcat accggccgtc aggccgatat cccagccgaa
    18961 tagcttacca aggcctaagg cgattagcag agcgctaccg accatgacca gggcaagcat
    19021 cagataattt ttaccgtcgc gaaaaaaaat cgaaaaaaag ttggggccag cctcgacgcc
    19081 gacacaaaaa ataaacagca taaatcccag atttagcgcg tcggtgttaa tactaaagtg
    19141 ttgctgccct aataatagag agaccactaa aacgccaatg gaattaccaa gttggactga
    19201 acccagacgt aacttgccaa gacacaggcc aagagccagg accacaaata ataacaggat
    19261 gtaattccca tttaacaaat ctgcgacgtt tatattcacg gagactaact tcttgtttac
    19321 gagtaagctg ttgaaagaaa tggtaattta cgctactgtt tttatcatga attaagggtg
    19381 caatcgtatt gcatacagca tccaaataaa aacaacacaa caatatatcc tgctagttta
    19441 atcttattgc gtactaacgg ctataagaat tgtgcaggtg tgtttttggc atggaatgcc
    19501 acatgacttt atctgactgg atgcctcacg gcggaaagcg tgttcgatag agagtgtcag
    19561 gaggaacggt tgaaacataa acacgggtgg gcaagcgttg tctgctgctt tgtactcttt
    19621 attgtggtgt gtctttcatt aactatgcat gtacaaggcg cttttcgcgc ggcagggcat
    19681 cctgagattg gactgttatt ttttacgttg cttggtgcgg tggccagttt ttgttctcac
    19741 cgacgcgagg tgatccgacc gctgatcggg gcgatgctgg cggcgccgtt ttgcctggtg
    19801 ttaatgcgcg tggtatttat gcctacccga tcgttttggc aagaactggc gtggttattt
    19861 agcgccgtat tctggtgtgc gttaggcgcg ctctgctatt tgtttattag cagcctgttt
    19921 agccaccggc gaaaaaaacg ccgatagcgc cctccggcag agggcgtcgc cagagcaatc
    19981 aggcgaaaag attcagattt tcttttgccc atgcttcaaa atccgtacag ccgccgatat
    20041 gtttttgatc gacaaaaatc tgcggtacgg tttctacagg tttacctacg gttttttcca
    20101 aatccgcttt agtaatgcct tcggcatgga tatcaatata gcggtagttg aaatcgtcgc
    20161 gttctttgct cagtttttcc gccaactctt ttgcacgcac gcaataaggg caccctgggc
    20221 ggccaaaaat aacagtaaac atatctctcc tcgaacataa agccagacgg cgaacaggtg
    20281 ttatcatgcc gcgatttacg gcagatgaaa agcaggttac gcctgttcct ttgataactc
    20341 agggctatat ctgttaagca cgccggacca gaacgttcta cactgtgcgt cagttaaccg
    20401 ggaggcttga tatgcgcacg atcggcgtgt tacccaaaag cgtactgata ctggaatgcc
    20461 tcggtatgat tttgctggcg cttgctctgc tatcgcttaa tcattacctt acgctgcccg
    20521 cgccgttcaa tacgtcgctg gctggcgtat tgatggtttt cctgggcgtc gtgttgatcc
    20581 tccccgccgc ggtggcgatg atgtggcgta ttgcgcagtt actggcgccg cagttgatga
    20641 aacgtccacc cgacatttct tcccgttcag atagagaaaa gcataatgag tccgaccatt
    20701 gaacttcttt gtggccatcg ttctattcgc catttcaccg atgaacccgt gactgacgcg
    20761 cagcgagagg ccattattgc cgccgcgcgc agcacgtcca gttccagttt tttacagtgc
    20821 agctctataa tccgtattac cgatcgggcg ctgcgcgagg cgttagtgcc cctgacgggc
    20881 gggcaaaagc atgtggcgca ggccgctgag ttctgggtat tttgtgccga ttttaatcgt
    20941 catttgcaga tctgtcctga cgcgcagttg gggcttgccg aacaactgct gctcggtgtc
    21001 gtcgatacgg cgatgatggg gcaaaacgcg ctgacggcgg cggaatcact ggggttaggc
    21061 ggcgtgtata tcagcggcat ccgtaataat attgaatctg ttaccgaact attaaaattg
    21121 ccgaagcatg tattgccgct ctttggcctg tgtttgggat ggcctgcgga taatccggat
    21181 ctgaaaccgc gcctgcctgc cgagcttgtg gttcatgaga accagtatca accgcttgat
    21241 gaaaagctgc tggcgcgcta tgacgagcag ttggctgagt attatctgac ccgcggcagt
    21301 aatacgcgac gcgatacctg gagcgatcat atccgtcgca ccctgattaa agaaaatcgc
    21361 ccatttatcc ttgaatattt gcataaacag ggctgggcga cgcgctaaaa cctgcgggcc
    21421 agtgtatgat acgcgggctt ttcagggttt tcagcgaggt gcagggtgaa aattgccata
    21481 ttgtctaggg atggaacgct ctattcttgc aaacgtctgc gcgaagcggc gatgcggcgc
    21541 ggccatctgg tcgagatact cgatcctctt tcctgctata tgaatattaa tccggcagcg
    21601 tcgtcgatcc attacaaggg gcgtcgtctg ccccattttg acgccgttat tccccgtatt
    21661 ggttcggcca ttacctttta tggtaccgct gcgctacgtc agtttgagct actgggtagc
    21721 tatccgctga atgaatccgt cgctattacc cgcgcgcgcg ataagctgcg atcgctacaa
    21781 cttctggcgc gccaggggat cgatctcccc attaccggga tcgcccattc gccggatgat
    21841 accagcgatc ttattaagat ggttggcggg gcgccgctgg tcgtgaagct ggtagaaggc
    21901 acgcaaggga tcggcgtggt attggcggag acgcgtcagg ctgctgaaag cgttattgat
    21961 gcgtttcggg ggctgaatgc ccatatcctg gttcaggaat acattgccga agctaaagga
    22021 tgcgatattc gttgtctggt cgtcggcaat gaggttgtgg cggcgattga gcggtgcgcg
    22081 aaagccggtg attttcgctc caatcttcat cgtggcgggg tggccagcat cgcgacgatc
    22141 acgccccgtg aacgggatat cgccatcaaa gccgcacaga cgctggggct ggatgtggcg
    22201 ggtgtcgata ttttacgcgc cgcgcgcggg ccgctggtga tggaggtgaa tgcctcgccg
    22261 ggactggaag gtatcgaaaa gactacgggc gtggatatcg cggggcgaat gattcagtgg
    22321 atagaacgtc acgctacgcc tgaattttgc cttaaaatcg gcggctaatc gcaatcgtgg
    22381 attccgccgt agtacgaagc acgctttttg cgtaagctgt gccggtaatt ttttcatcgt
    22441 catcgtaaga ggtagcacat tattatgata tcactggtcg ttcccactct ggatacgttg
    22501 cgtcaatggc tcgacgacct gggcatgaat ttcttcgaat gtgatacctg ccaggcgctg
    22561 catttgccgc atatgcagaa ttttgacggc gtctacgatg ctaaaatcaa tttggtggac
    22621 aacaccgttc ttttttccgc gatggcggag gtcaggcctt ccgcgttgct gccgctggcg
    22681 gccgatctct ctgctatcaa cgccagttcg ttgacggtaa aagcctttct cgatatgcag
    22741 gatgataatc tgccaaaact ggttgtgtgc cagtctttat ccgttatgca aggcgtcacc
    22801 tacgagcagt tcgaatggtt tgttcgccaa agtgaagagc agatttctat ggtgatcctt
    22861 gaggccgggg cgcatcagct tctgtttaac gcggaagaag acgcgcaaaa aaccagcgcg
    22921 gttgaccatt ttcttcactg atccctcccg ataatcaggc agtcgctgcc agcgcggctg
    22981 ctgtttacgt ttttttatgc tgctgttaac ctttatttaa agaattattc acctcctttc
    23041 tggccatttc gctttatcac atagacaaaa cctgcataaa aaattgataa aaggcgtttt
    23101 ttaatctggg ctatagcctc aaaccttagc taaagttatt cttgcgaagc ttctatagcg
    23161 agcttgatgg cagggagggc gacctctctt cttcatttgt atcaaatgaa aaggtatgca
    23221 catttcaggc atgttttaaa ccacgcctaa tgggttcatt tgttaacgga ttttagaagg
    23281 aaagcgatga tgaccgcctt aaagaaaaaa tggctatcgg gtctggttgc gggtgctctg
    23341 atggtcgtct ctgtcggcac gctcgctgcc gaacaaaaaa cgctgcacat ttataactgg
    23401 tcagattata tcgcgccgga cacggtggcg aactttgaaa aagagaccgg gattaacgtt
    23461 atctatgatg tctttgactc taacgaagtg ctggaaggca agttaatggc aggcagcacc
    23521 gggttcgatc tggtggtgcc atcggccagt tttcttgagc gccagctcac cgcgggcgtt
    23581 tttcagccgc tggataaaag caaacttccc ggctggaaaa acctcgatcc tgaactgctg
    23641 aaactggtag cgaagcacga tcctgacaac aaatacgcca tgccctatat gtgggccacg
    23701 acgggcattg gctataacgt tgataaagtg aaagcggtgc tgggggatga tgcgccagtg
    23761 aatagctggg atttagtcct caagccggaa aatctggaga agctaaaaag ctgcggcgtc
    23821 tctttccttg atgcgcctga agaaattttt gccaccgtgc tgaattatct gggtaaagat
    23881 ccgaatagca gcaaagcgga tgactacacc ggcccggcaa ccgatctgtt gttgaagcta
    23941 cggccaaaca ttcgctattt ccactcctcg caatacatta acgatctggc taatggcgat
    24001 acctgtgtgg ccatcggctg ggcgggcgat gtctggcagg ccgctaaccg ggcgaaagag
    24061 gcgaaaaatg gcgtcaatat ctctttctcg atccccaaag agggggtaat ggcatttttt
    24121 gatgtgtttg ccatgccggc tgacgccaaa aataaagacg aggcctacca gttccttaat
    24181 tatctgctgc gccttgatgt gattgctcat atttccgatc acgttttcta cgccaatgcg
    24241 aataaagagg cgacggcgct ggtcagccag caggtgcgcg ataacccagg aatttatccg
    24301 ccggcggatg tgcgggccaa gttgtttacc ctgaaagtgc aggagccgaa gattgatcgc
    24361 gtccgcaccc gcgcatggac gaaggtgaaa agcggtaagt aatttattaa cggtatggcc
    24421 tgataagcgt gcgctatcgg gcattccacc gtttgtatcg tttgattgtg ttatgccgga
    24481 gagcgccttg tgaatgatgc cccccaccgc ccgcaggtga aaacccgtaa agcgctgacg
    24541 ccgcttctgg aaattcgcaa cctgacgaag tcattcgacg ggcaacatgc tgtcgatgat
    24601 gtcagtctga ctatctataa aggtgagatt tttgccctgc tgggcgcgtc aggttgtgga
    24661 aaatcgactc tgttacggat gctggcgggt tttgaaccgc cgagcagcgg gcaaattatg
    24721 ctcgacggcg tcgatctggc gcatgttccg ccgtatcagc gtccgattaa tatgatgttt
    24781 cagtcctatg cgttgtttcc gcatatgacg gtagagcaga acatcgcttt tggtctgaag
    24841 caggacaaac tgccgaaggc ggagattacc agccgcgtca atgagatgct gggtctggtg
    24901 cacatgcagg agtttgcaaa acgtaagccg catcagcttt ccggcggtca gcgtcagcgc
    24961 gtggccctgg cgcgcagcct ggcgaaacgt cttaagctgc tcttgttgga tgaaccgatg
    25021 ggcgcgctgg ataaaaaatt acgcgaccgg atgcagctgg aagtggtgga tatccttgag
    25081 cgcgtcggcg tgacttgcgt catggtgacg cacgatcagg aagaagccat gacgatggcg
    25141 gggcgcattg ccatcatgaa ccgtggaaaa tttgtgcaaa ttggcgaacc ggaggagatt
    25201 tacgagcatc cgacaacccg ctatagcgcc gaatttatcg gatcggtaaa tgtttttgag
    25261 ggcttactga aagcgcgtga agaggacggt ctggtcattg acgcgcccgg tttggttcat
    25321 ccgttaaaag tcgatgcaga tgcctctgtc gttgataatg tgccggtata tgtggcgcta
    25381 cgtccggaaa aaatcatgct gtgtgagtcg ccgcctgccg atggctataa tttcgccgtc
    25441 ggcgaagtgg cgcatattgc gtatctcggc gatctgtcta tttatcatgt gcggctaaaa
    25501 agcgggcaga tgatcagcgc tcaactgcag aatgcgcacc gttaccggaa agggttaccg
    25561 acctggggcg atgaagtgcg tttgtgctgg gaagcggata gctgcgtggt cctgacggta
    25621 taagggggaa acatgagcac acttgaacct ccggcacgca tcagtaaacc tggcggcgcg
    25681 gcgctatggt tggcgcgaat gcaaatgaaa catgggcgta agctggttat tgctttgcct
    25741 tatatctggc tcattctgct gtttttactg ccgtttctta tcgtctttaa gataagcctg
    25801 gcggaaatgg cgcgggcgat cccgccgtat accgatctgc tggaatgggc tgacggtcag
    25861 ttgtcgatta cgctcaacct cggcaatttt ttgcaactga ccgacgatcc gctctatttc
    25921 gaagcctgtc tgcaatcgtt acaaattgcc ggtatttcca caatctgctg cctgctgctg
    25981 ggctacccgc tggcgtgggc ggtggcgcac agcaagccct ccacgcgcaa tatcctgctg
    26041 ctgttggtga ttctgccctc gtggacgtct tttttaatac gcgtctatgc ctggatgggc
    26101 attttgaaaa acaacggtgt gctgaacaat gtgttgctgt ggctaggggt tatcgatcag
    26161 ccgctgacga tcctgcacac taacctggcc gtctatatcg gcattgttta tgcgtatctg
    26221 ctgtttatgg ttctgcccat ttataccgcg ttgacgcgca ttgattattc gctggtggaa
    26281 gcgtcgctgg atctcggcgc ccgaccgatg aaaacatttt ttagcatcat tgtcccgctc
    26341 accaaaggcg gaatcatcgc cggctcgatg ctggttttta tcccggcggt gggcgagttc
    26401 gtgatcccgg aactgcttgg cgggccggac agtatcatga ttggtcgcgt cctgtggcag
    26461 gagtttttca ataaccgcga ctggccggtg gcttctgcgg tcgccattat tatgttgctg
    26521 ctgctgatag tcccgatcat gtggttccat aaacatcagc aaaaaagtgt gggggagcac
    26581 ggatgaataa cttaccggtc gttcgctcgc cctggcgcat tctgattctg gtgctggggt
    26641 ttacttttct ctatgcgccg atgttaatgt tggtgattta ctcgtttaac agttcgaagc
    26701 tggtgacggt gtgggcggga tggtcgacgc gctggtatgg cgagctcttt cgggataccg
    26761 ccatgatgag cgcagtggga ctaagcctga caattgccgc ctgcgcggcg acgatggcgg
    26821 tggtgctcgg tactatcgcc gcggtggtga tggtgcgatt tggacgattt cgcggcgcaa
    26881 acggctttgc gtttatgatc accgcgccgc tggtgatgcc ggatgtgatt accgggctgt
    26941 cgctgctgct gctgtttgtc gcgctcggtc atactatcgg ctggccctcc gatcgcggaa
    27001 tgctgaccat ctggttggcg cacgtcactt tctgtaccgc ctatgtggca gtggtgatcg
    27061 cttcgagatt acgcgaactg gatcgttcga ttgaagaggc ggcgatggat cttggcgcgg
    27121 cgccgttgaa ggtctttttt gtcattacgt taccgatgat catgccagcg gtgatctcgg
    27181 gctggctgtt ggcctttacg ctctcccttg acgatctggt gattgccagc ttcgtttccg
    27241 gtcccggcgc caccacgcta ccgatgctgg ttttctccag cgtgcgcatg ggtgtgaacc
    27301 cggaaatcaa cgcgctggcg acgttaatcc tcggcgtggt aggaatcatc ggatttattg
    27361 cctggtacct gatggcgcga gcggaaaaac agcggattcg cgatatccag cgtgcaagac
    27421 gcggctgaag ccactaaaat cttccactat ggcaatgcgt tgccgcgcga gtcgcggcat
    27481 cattttcagg gaagacattc attgggattt ataaagcaat caacctcatc acatgcccgt
    27541 ttaaatgtgc ctacgctggt gcaggttgcg gctatggcga ttattttgat tcgcggtctc
    27601 gatgtgctga tgattatgaa taccctcggc atacgcggga tgggcgagtt tattcatcgc
    27661 agcgtgcaga cgtggagctt aaccctggtc tttctggcca gcttagtgct ggtctttatt
    27721 gaaatttatt gtgcgttttc gctggtgaaa ggccgtagct gggcgcgctg ggtgtacctg
    27781 gcggcacaaa ttattgtgag tgggtatctg tgggcggcgt cgttaggcta cgggtatccg
    27841 gagttgttta gcatcgcggg agaatcgaag cgtgatatcc tgcattccct ggtcatgcaa
    27901 aaactccccg atcttttaat tctgtttctg ctgtttattc ccgctcccag ccgtcggttc
    27961 ttccggctgc aataatgtgt ataatcgtca ccccggataa tatgaaggtt ttttggtatg
    28021 cagtgcgcac tctatgacgc gggtcgctgc cgttcctgtc aatggattac gcagtcggtt
    28081 aacgaacaac tttccgcaaa aacagccgat ttacatcgtt tgctggccgg gctgcctgtt
    28141 gaacagtggt gcgcgccgat tagcggcccg gaacagcatt tccgcaacaa agcgaaaatg
    28201 gtcgtgagcg gtagtgtaga aaaaccgctc ttcgggatgc tgcatcgcga cggtacgccg
    28261 gtcgatcttt gcgcttgccc gctgtatccc gcctcctttg cccccgtatt cagcgcgcta
    28321 aaacctttta ttgcccgtgc cggactcacg ccttataacg tggcgcgaaa acgcggcgaa
    28381 ctgaaatacc tgttgctgac ggaaagtcag ttcgatggcg gcatgatgct acgcttcgtg
    28441 ttgcgttcag aaaccaaact tacgcaactg cgcgcggcgt taccgtggct gcgcgcgcaa
    28501 ctgccgcagc tcagagtgat cactgcgaat atccagccgg tacatatggc gattatggaa
    28561 ggggagacgg aaatctatct gacggatcag caggcgctgg cggaacgttt taacgatgtg
    28621 ccgctgtgga ttcgtccgca aagtttcttt cagaccaacc ctacggtcgc cagccgatta
    28681 tatgcgacgg cgcgcgactg ggtagggcaa ttgccggtac gccatatgtg ggatcttttt
    28741 tgcggagtgg gcggattcgg cctgcactgc gcgacgccgc agatgcaatt aaccggtatt
    28801 gagatcgcgc cggaggcgat tgcctgcgcg aagcaatccg ctgccgagct gggattaacc
    28861 cgccttcatt tctaggcgct ggattccacc caattcgcca ccgcacaagg cgaaacgccc
    28921 gatctggtgt tggtgaatcc tccccgccgc ggcattggca agccgttgtg cgattacctt
    28981 gcacaaatgg cgccgcgttt tatcatttat tcgagctgta acgcgcagac gatggcgcag
    29041 gatattcgcc atctgccgaa ctaccgtatt caacgtgttc agcttttcga tatgttcccc
    29101 cataccgcgc attatgaagt gttaacactg ctttgcaggc tgtagcgcca aaagccaagc
    29161 at
//
LOCUS       DAJVBX010000028        29011 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.028, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000028 DAJVBX010000000
VERSION     DAJVBX010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 29011)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29011)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29011
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.028"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(51..1259)
                     /locus_tag="OPV72_001125"
     CDS             complement(51..1259)
                     /locus_tag="OPV72_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR9913488.1"
                     /translation="MTYRSKVAVVYLLGFFLDLINLFIASVAFPAMSVDLHTSISALA
                     WVSNGYIAGLTLIVPFSAFLSRYLGARRLIIFSLILFSVAAAAAGFADSLHSLVFWRI
                     VQGAGGGLLIPVGQALTWQQFKPHERAGVSSVVMMVALLAPACSPAIGGLLVETCGWR
                     WIFFATLPVAVLTLLLAYRWLNVASTTMASARLLHLPLLTDKLLRFAMIVYLCVPGMF
                     IGISVVGMFYLQNVAQLSPAAAGSLMLPWSIASFVAIMLTGRYFNRLGPRPLIIVGCL
                     LQAAGILLLTNVTPATSHRVLMMIFALMGAGGSLCSSTAQSGAFLTIARRDMPDASAL
                     WNLNRQLSFFLGATLLTLLLNALQRVMSLEVAYRWTFIAAAGITLLPLIYAVCLNNRQ
                     ALLCLKKERS"
     gene            1347..2279
                     /locus_tag="OPV72_001126"
     CDS             1347..2279
                     /locus_tag="OPV72_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCR9913489.1"
                     /translation="MTVKELAMLNLQRMSLFVAVVDSGSFTAAAAASGQTKAVVSFNI
                     RQLEKELGVTLLLRSTRRLTLTDAGVLFYQKGVNLLNAAKNLQDEVRASHSGLGGELR
                     ITTTPEFGEQVVIPVLAQFSQRHPDLRIRHMSSSHHADLIAERFDVAIRLGSLADSRY
                     RAALISRFTILPVAAPQWLARHPVSSLESLAQAEWIIHERLPTPLRWTVTNNHGQHSR
                     LEISKAGKISVDSARSLMAFALAGSGVALLPQWLVNTALEDGTLIHVLPDYHFPRQGI
                     YAVYPDARHVSTKVRAFIDFLRSQWDCGEHAPSL"
     gene            complement(2321..3817)
                     /locus_tag="OPV72_001127"
     CDS             complement(2321..3817)
                     /locus_tag="OPV72_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HCR9913490.1"
                     /translation="MTSLPTPIIGLIVAVFVLVWLVLRTRVHALIAMLAAACIAGLLG
                     GMGIDKTLSVITSGFGTTLGSIGLVIGLGVMMGRLLEVSGAAERIAWSFIKWLGKRRE
                     EWALAITGYIVSIPIFVDSAFVILYPVAKALAKSGKRSLLTLGVALAGGLVVTHHTVP
                     PTPGPLGVAGIFNVDIGAMLLTGMALAVPCVIGIVFYAQWLDKRYPDFVPRTLNADEV
                     NAALEQYNKEKEQKDLPSLTLSLLPIVVPIVLIFLKAICSTLATVEGWSGLATHPVVQ
                     AINFVGSPVIALAISVLLAVYTLVPRMDKHTTAERLEEGLQSAGIILLVTGAGGALGA
                     ILRDSGAGQQLAEQVANLPISPILIPFIVATLVRLIQGSGTVAMITAASISAPILAQI
                     PGINMLLAAQAATMGSLFFGYFNDSLFWVVNRMMGVSDVKQQMVVWSVPTTIAWAIGG
                     TGVALINLLFGSGGSWLDPLLPIVVLAAIMLWVRWQAQGIKDKLVVKD"
     gene            complement(3814..4764)
                     /locus_tag="OPV72_001128"
     CDS             complement(3814..4764)
                     /locus_tag="OPV72_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCR9913491.1"
                     /translation="MQIIITGGGGFLGQKLASALLNSSLAFNELLLVDLKMPARLSDS
                     PRLRCLEADLTQPGVLENVITANTSVVYHLAAIVSSHAEDDFDLGWKVNLDLTRQLLE
                     ACRRQPQKIRFVFSSSLAVYGGTLPECVTDTTALTPRSSYGAQKAACELLVNDYTRKG
                     YVDGLALRLPTICVRPGKLNRAASSFVSAIIREPLQGETTICPVSESLRLWISSPATV
                     IHNLSLAATLPAPGEASSINLPGISVTVGEMLETLRQAGGQAARDRVTHQRDEGVEKI
                     VASWPGRIDNQRALALGFVADKRFDDIIERFRQDDMEGRS"
     gene            complement(4804..5580)
                     /locus_tag="OPV72_001129"
     CDS             complement(4804..5580)
                     /locus_tag="OPV72_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HCR9913492.1"
                     /translation="MPRFAADLSMMFTEVPFIERFAAAAEAGFQAVEFLFPYGFAASE
                     IKAQLSRHDLTLALFNTSAGDTAAGEWGRAALPGREHDARADIDLALEYALALECEQV
                     HIMAGVVPDGADGARYRATFIDNLRYAAGRFAAHDKRILIEALSPGVKPGYLFSSQYQ
                     ALGIAEEVDRPNVFIQLDTFHAQKVDGNLSHLIREYAGRYAHVQIASLPDRHEPDDGE
                     INYPWLFRLFDDVGYCGWIGCEYQPRNTTQEGLGWFNAWR"
     gene            complement(5585..6223)
                     /locus_tag="OPV72_001130"
     CDS             complement(5585..6223)
                     /locus_tag="OPV72_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HCR9913493.1"
                     /translation="MTILAKEEHALREEMVRIAASFFQRGYATGSAGNLSLLLPDGNI
                     LATPTGSCLGNLDPQRLSKVDPQGEWLSGDKPSKEVRFHLALYRNNPCCKAVVHLHST
                     WSTALSCLEGLDPQNVIRPFTPYVVMRMGDIPLVPYYRPGDDRIARDLAALAARHQAF
                     LLANHGPVVCGENLQEAANNTEELEETAKLIFILGERPIRYLTTEEIAQLRR"
     gene            complement(6220..7005)
                     /locus_tag="OPV72_001131"
                     /pseudo
     CDS             complement(6220..7005)
                     /locus_tag="OPV72_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461838.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxo-tetronate kinase"
     gene            complement(7096..7521)
                     /locus_tag="OPV72_001132"
     CDS             complement(7096..7521)
                     /locus_tag="OPV72_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001613336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HCR9913494.1"
                     /translation="MIMTTGTDFHVGIVGLGSMGMGAARSCLRAGLSTWGADLNPQAC
                     ANLLAEGACGAAASAREFAGVVDALVILVVNAAQVRQVLFGEDGVAHLMKPGSAVMVS
                     STISSADAQEIAAALTALNLNMLDAPVSGGAVKAAQGGR"
     gene            7712..8476
                     /locus_tag="OPV72_001133"
     CDS             7712..8476
                     /locus_tag="OPV72_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCR9913495.1"
                     /translation="MIPTERRQIILDMVAEKGIVSIAELTERMHVSHMTIRRDLQKLE
                     QQGAVIQVSGGVQSSTRVAHEPSHQIKTELATPQKAAIGKLAASLVQPESCIYLDAGT
                     TTLAIARQLVTMNKLTVVTNDFVIADYLMDNSGCTIIHTGGAVCRENRSCVGEAAATL
                     LRGLMIDQAFISASSWSVRGISTPAEDKVTVKRAVASASRQKILVCDATKYGQVATWL
                     ALSLAEFNQIVTDDGLPESAIRALAKVDISLLMAKQ"
     gene            complement(8495..8899)
                     /locus_tag="OPV72_001134"
     CDS             complement(8495..8899)
                     /locus_tag="OPV72_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HCR9913496.1"
                     /translation="MELRNTAFHLLRQLFQQHTARWQHELPELTKPQYAVMRVIAEHP
                     GIEQVDLTEAAVSTKATLAEMLSRMENRGLVKRENDPLDKRRRFVYLTVQGQTLLAAA
                     IPLGDRVDDEFLGRLSAEEREQFTQLVRKMMT"
     gene            9070..9663
                     /locus_tag="OPV72_001135"
     CDS             9070..9663
                     /locus_tag="OPV72_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HCR9913497.1"
                     /translation="MRLIVGMTGATGAPLGVELLQALRAIPDVETHLVMSKWAKTTIE
                     LETPYTPAEVAALADYCHSPADQAATISSGSFRTDGMIIIPCSMKTLAGVRAGYADGL
                     VGRAADVVLKEGRKLVLVPREMPLSTIHLENMLALSRMGVAIVPPMPAFYNLPQTVDD
                     IIQHIVARVLDQFGLEHTRARRWQGLRQAANFSQENG"
     gene            9663..11090
                     /locus_tag="OPV72_001136"
     CDS             9663..11090
                     /locus_tag="OPV72_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HCR9913498.1"
                     /translation="MAFDDLRSFLHALDQQGQLLKISEEVNAEPDLAAAANATGRIGD
                     GAPALWFDNIRGFTDARVAMNTIGSWQNHAISLGLPPNTPVKKQIDEFIRRWDNFPVA
                     PERRANPGWAENTVDGDAINLFDILPLFRLNDGDGGFYLDKACVVSRDPLDPDNFGKQ
                     NVGIYRMEVKGKRKLGLQPVPMHDIALHLHKAEERGEDLPIAITLGNDPIITLMGATP
                     LKYDQSEYEMAGALRESPYPIATAPLTGFDVPWGSEVILEGVIESRKREIEGPFGEFT
                     GHYSGGRNMTVVRIDKVSYHSKPIFESLYLGMPWTEIDYLMGPATCVPLYQQLKAEFP
                     EVQAVNAMYTHGLLAIISTKKRYGGFARAVGLRAMTTPHGLGYVKMVIMVDEDVDPFN
                     LPQVMWALSSKVNPAGDLVQLPNMSVLELDPGSSPAGITDKLIIDATTPVAPDNRGHY
                     SQPVVDLPETKAWAEKLTAMLANRK"
     gene            11101..11337
                     /locus_tag="OPV72_001137"
     CDS             11101..11337
                     /locus_tag="OPV72_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913499.1"
                     /translation="MICPRCADAHIELMATSPVKGVWTVYQCQHCLYTWRDTEPLRRT
                     SREHYPQAFRMTQKDIDDAPMVPSIPPLLAEDKR"
     gene            complement(11382..12374)
                     /gene="rpoS"
                     /locus_tag="OPV72_001138"
     CDS             complement(11382..12374)
                     /gene="rpoS"
                     /locus_tag="OPV72_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoS"
                     /protein_id="HCR9913500.1"
                     /translation="MSQNTLKVHDLNEDAEFDENGVEAFDEKALSEEEPSDNDLAEEE
                     LLSQGATQRVLDATQLYLGEIGYSPLLTAEEEVYFARRALRGDVASRRRMIESNLRLV
                     VKIARRYGNRGLALLDLIEEGNLGLIRAVEKFDPERGFRFSTYATWWIRQTIERAIMN
                     QTRTIRLPIHIVKELNVYLRTARELSHKLDHEPSAEEIAEQLDKPVDDVSRMLRLNER
                     ITSVDTPLGGDSEKALLDILADEKENGPEDTTQDDDMKQSIVKWLFELNAKQREVLAR
                     RFGLLGYEAATLEDVGREIGLTRERVRQIQVEGLRRLREILQTQGLNIEALFRE"
     gene            complement(12437..13558)
                     /gene="nlpD"
                     /locus_tag="OPV72_001139"
     CDS             complement(12437..13558)
                     /gene="nlpD"
                     /locus_tag="OPV72_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein hydrolase activator NlpD"
                     /protein_id="HCR9913501.1"
                     /translation="MSAGSPKFTVSRIAALSLVSLWLAGCTSSSNPPAPVTSVDSGSS
                     SNTNSGMLITPPPKMGATPQQAPQIQPVQRPVTQPMQTQPVTEQPVQMENGRIVYNRQ
                     YGNIPKGSYTGGSTYTVKKGDTLFYIAWITGNDFRDLAQRNSISAPYSLNVGQTLQVG
                     NASGTPITGGNAITQADAAQQGVVTRSAQNSTVAVASQPTITYSEGSGEQSANKMLPN
                     NKPAGTVVTAPVTAPTVSTTEPNASSTSTSAPISAWRWPTDGKVIENFGASEGGNKGI
                     DIAGSKGQAIVATADGRVVYAGNALRGYGNLIIIKHNDDYLSAYAHNDTMLVREQQEV
                     KAGQKIATMGSTGTSSTRLHFEIRYKGKSVNPLRYLPQR"
     gene            complement(13734..14360)
                     /locus_tag="OPV72_001140"
     CDS             complement(13734..14360)
                     /locus_tag="OPV72_001140"
                     /EC_number="2.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-L-isoaspartate(D-aspartate)
                     O-methyltransferase"
                     /protein_id="HCR9913502.1"
                     /translation="MVSGRVQALLEQLRAQGIRDELVLNALAAVPREKFIDEAFEHKA
                     WENIALPIGQGQTISQPYMVARMTELLELTPQSRVLEIGTGSGYQTAILAHLVHHVCS
                     VERIKGLQWQARRRLKQLDLHNVSTRHGDGWQGWQARAPFDAIIVTAAPPEIPTALMA
                     QLDEGGILVLPVGDEQQFLKRVRRRGGEFIIDTVEAVRFVPLVKGELA"
     gene            complement(14354..15115)
                     /gene="surE"
                     /locus_tag="OPV72_001141"
     CDS             complement(14354..15115)
                     /gene="surE"
                     /locus_tag="OPV72_001141"
                     /EC_number="3.1.3.5"
                     /EC_number="3.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'/3'-nucleotidase SurE"
                     /protein_id="HCR9913503.1"
                     /translation="MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNS
                     LTLESSLRTFTFDNGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVI
                     YSGTVAAAMEGRHLGFPALAVSLNGYQHYDTAAAVTCALLRGLSREPLRTGRILNVNV
                     PDLPLAQVKGIRVTRCGSRHPADKVIPQEDPRGNTLYWIGPPGDKYDAGPDTDFAAVD
                     EGYVSVTPLHVDLTAHSAHDVVSDWLDSVGVGTQW"
     gene            complement(15096..16145)
                     /gene="truD"
                     /locus_tag="OPV72_001142"
     CDS             complement(15096..16145)
                     /gene="truD"
                     /locus_tag="OPV72_001142"
                     /EC_number="5.4.99.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(13) synthase TruD"
                     /protein_id="HCR9913504.1"
                     /translation="MTEFDNLTWLHGKPQGSGLLKANPEDFVVVEDLGFTPDGEGEHI
                     LLRILKNGCNTRFVADVLAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDFS
                     AFQLEGCKVLEYARHKRKLRLGALKGNAFTLVLREISDRRDVETRLQAIRDGGVPNYF
                     GAQRFGIGGSNLQGALRWAQSNAPVRDRNKRSFWLSAARSALFNQIVHQRLKKPDFNQ
                     VVDGDALQLAGRGSWFVATSEELPELQRRVDEKELMITASLPGSGEWGTQRAALAFEQ
                     DAIAQETVLQSLLLREKVEASRRAMLLYPQQLSWNWWDDVTVELRFWLPAGSFATSVV
                     RELINTMGDYAHIAE"
     gene            complement(16142..16621)
                     /gene="ispF"
                     /locus_tag="OPV72_001143"
     CDS             complement(16142..16621)
                     /gene="ispF"
                     /locus_tag="OPV72_001143"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HCR9913505.1"
                     /translation="MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHAL
                     TDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQA
                     PKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLMKAAK"
     gene            complement(16621..17331)
                     /gene="ispD"
                     /locus_tag="OPV72_001144"
     CDS             complement(16621..17331)
                     /gene="ispD"
                     /locus_tag="OPV72_001144"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HCR9913506.1"
                     /translation="MAATLLDVCAVVPAAGFGRRMQTECPKQYLSIGNKTILEHSVHA
                     LLAHPRVTRVVIAISPGDHRFAQLPLANHPQITVVDGGNERADSVLAGLQAVAKAQWV
                     LVHDAARPCLHQDDLARLLAISENSRVGGILASPVRDTMKRGEPGKNAIAHTVERADL
                     WHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPALVEGRADNIKVTRPE
                     DLALAEFYLTRTIHQEKA"
     gene            complement(17350..17661)
                     /gene="ftsB"
                     /locus_tag="OPV72_001145"
     CDS             complement(17350..17661)
                     /gene="ftsB"
                     /locus_tag="OPV72_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsB"
                     /protein_id="HCR9913507.1"
                     /translation="MGKLTLLLLALLVWLQYSLWFGKNGIHDYSRVNDDVVAQQATNA
                     KLKARNDQLFAEIDDLNGGQEAIEERARNELSMTKPGETFYRLVPDASKRAATAGQTH
                     R"
     gene            complement(17852..18175)
                     /locus_tag="OPV72_001146"
     CDS             complement(17852..18175)
                     /locus_tag="OPV72_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011233164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3561 family protein"
                     /protein_id="HCR9913508.1"
                     /translation="MRNSHNITFTRSDAFMVDDDATSAFPGAVVGFVSWLLALGIPFL
                     LYGPNTLFFFLYTWPFFLALMPVSVIIGIALHLLVKGKILFSIMFTLLAVGALFGALF
                     IWLLG"
     gene            complement(18226..18831)
                     /gene="cysC"
                     /locus_tag="OPV72_001147"
     CDS             complement(18226..18831)
                     /gene="cysC"
                     /locus_tag="OPV72_001147"
                     /EC_number="2.7.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylyl-sulfate kinase"
                     /protein_id="HCR9913509.1"
                     /translation="MALHDENVVWHSHPVTVAAREQLHGHRGVVLWFTGLSGSGKSTV
                     AGALEEALHQRGVSTYLLDGDNVRHGLCRDLGFSDADRQENIRRVGEVASLMADAGLI
                     VLTAFISPHRAERQLVKERVGHDRFIEIYVNTPLAICEQRDPKGLYKKARAGELRNFT
                     GIDAIYEAPDSPQVHLNGEQLVTNLVSQLLDLLRRRDIIRS"
     gene            complement(18818..20257)
                     /gene="cysN"
                     /locus_tag="OPV72_001148"
     CDS             complement(18818..20257)
                     /gene="cysN"
                     /locus_tag="OPV72_001148"
                     /EC_number="2.7.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate adenylyltransferase subunit CysN"
                     /protein_id="HCR9913510.1"
                     /translation="MNTILAQQIASEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLI
                     GRLLHDTLQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYF
                     STEKRKFIIADTPGHEQYTRNMATGASTCDLAILLIDARKGVLDQTRRHSFISTLLGI
                     KHLVVAINKMDLVDYREETFARIREDYLTFAEQLPGDLDIRFVPLSALEGDNVAAQSA
                     NMRWYSGPTLLEVLETVDIQRAVDRQPMRFPVQYVNRPNPDFRGYAGTLASGSVKVGE
                     RIKVLPSGVESSVARIVTFDGDKEEVCAGEAITLVLNDDIDISRGDLLLAANETLAPA
                     RHAAIDVVWMAEQPLAPGQSYDVKLAGKKTRARIEAICYQIDINNLTQRDVESLPLNG
                     IGLVEMTFDEPLALDIYQQNPVTGGLIFIDRLSNVTVGAGMVRELDERGATPPVEYSA
                     FELELNALVRRHFPHWDARDLLGDKHGAA"
     gene            complement(20267..21175)
                     /gene="cysD"
                     /locus_tag="OPV72_001149"
     CDS             complement(20267..21175)
                     /gene="cysD"
                     /locus_tag="OPV72_001149"
                     /EC_number="2.7.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate adenylyltransferase subunit CysD"
                     /protein_id="HCR9913511.1"
                     /translation="MDQKRLTHLRQLEAESIHIIREVAAEFANPVMLYSIGKDSSVML
                     HLARKAFYPGTLPFPLLHVDTGWKFREMYAFRDRTANAYGCELLVHKNPEGVAMGINP
                     FVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDP
                     KNQRPELWRNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLE
                     RDGMLMMVDDDRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESHAQTLPEIIEEMLVST
                     TSERQGRMIDRDQAGSMELKKRQGYF"
     gene            21426..22472
                     /locus_tag="OPV72_001150"
     CDS             21426..22472
                     /locus_tag="OPV72_001150"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HCR9913512.1"
                     /translation="MFSATRRFAVILALGVGFILPAQAASPGPGEIANTQARHIATFF
                     PGRMTGSPAEMLSADYLRQQFTQMGYQSDIRTFNSRFIYTTKDNRKNWHNVTGSTVIA
                     AHEGRVPQQIIIMAHLDTYAPQSDADVDANLGGLTLQGMDDNAAGLGVMLELAARLKD
                     IPTHYGIRFIATSGEEEGKLGAENLLKRMSDAEKKNTLLVINLNNLIVGDKLYFNSGK
                     NTPEAVRTLTRDRALAIARRYGIAANTNPGRNPSYPKGTGCCNDAEVFDKAGISVLSV
                     EATNWNLGKKDGYQQRVKNASFPNGNSWHDVRLDNQQHIDKALPGRIERRSRDVVRIM
                     LPLVKELAKAEKTS"
     repeat_region   22487..22907
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=22550..22577
                     /rpt_unit_seq="ggtttatccccgctggcgcggggaacac"
     gene            complement(22992..23285)
                     /gene="cas2"
                     /locus_tag="OPV72_001151"
     CDS             complement(22992..23285)
                     /gene="cas2"
                     /locus_tag="OPV72_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated endoribonuclease
                     Cas2"
                     /protein_id="HCR9913513.1"
                     /translation="MSMLVVVTENVPPRLRGRLAVWLLEIRAGVYVGDVSAKIREMIW
                     QQVSVLADEGNVVMAWATNTESGFEFQTFGVNRRIPVDLDGLRLVSFLPVENQ"
     gene            complement(23288..24205)
                     /gene="cas1e"
                     /locus_tag="OPV72_001152"
     CDS             complement(23288..24205)
                     /gene="cas1e"
                     /locus_tag="OPV72_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated endonuclease Cas1"
                     /protein_id="HCR9913514.1"
                     /translation="MSWLPLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGVRTHI
                     PVGSVACIMLEPGTRVSHAAVRLAATVGTLLVWGGEAGVRVYASGQPGGARSDKLLYQ
                     AKLALDEDLRLKVVRKMFELRFGEPAPSRRSVDQLRGIEGSRVRATYALLAKQYGVKW
                     QGRRYDPKDWEKGDVINQCISSATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYD
                     IADIIKFEIVVPKAFEIARRNPAEPDRDVRIACRDIFRSGKTLAKLIPLIEDVLAAGE
                     IQPPLPPEDSHPIAIPLPVALGDSGHRST"
     gene            complement(24205..24909)
                     /gene="cas6e"
                     /locus_tag="OPV72_001153"
     CDS             complement(24205..24909)
                     /gene="cas6e"
                     /locus_tag="OPV72_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001748704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein
                     Cas6/Cse3/CasE"
                     /protein_id="HCR9913515.1"
                     /translation="MYLSRIQLRFNNLRPEMLAKWNSARPYASHQWLWQLFPEQELRQ
                     FLFREEAHGGFFMLSAIPPLLQHSLFLIETKLFNPQLTNGLELDFQLRANPVITRNGK
                     RSDVMMNAKHQAKANGVEKERWWELQQQAAQAWLEQQGQQHGFRLIAPEPDDFAMWAG
                     DEYSELQAHCGCVQAYQQHRFVRKDQETPITFSSVDFSGALCITDAALFKQALFSGLG
                     KSKALGCGMLMVKRKR"
     gene            complement(24909..25634)
                     /gene="cas5e"
                     /locus_tag="OPV72_001154"
     CDS             complement(24909..25634)
                     /gene="cas5e"
                     /locus_tag="OPV72_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000666428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein Cas5/CasD"
                     /protein_id="HCR9913516.1"
                     /translation="MKEYLVFQLYAPLASWGEEASGEIRHSATVPTRSALLGLLAAAL
                     GIRRDEEARLNNFNRHYHLAVHALASQDRWLRDYHTVSAPRENKKYRYYTRRDELTLA
                     SDEVGTLISQREYRCDGYWHVAISATPDAPYSLSELREALLTPHFPLYLGRKSCPLAL
                     PLAARLMTGTLKEVFTHAVEEISAAELSGFTLREGICYWDDPDEESLVWQQKQHSNNQ
                     PVSRQRWQFGGYTRFNGPLQERT"
     gene            complement(25644..26702)
                     /gene="cas7e"
                     /locus_tag="OPV72_001155"
     CDS             complement(25644..26702)
                     /gene="cas7e"
                     /locus_tag="OPV72_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001804435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein
                     Cas7/Cse4/CasC"
                     /protein_id="HCR9913517.1"
                     /translation="MTTFIQLHLLTAYAPANLNRDESGRPKTAFMGGVERLRVSSQSL
                     KRAWRVSETFEAAMDGFMGKRTRRIGVDYVYRPMKDAGIEEKIAKSSSELIAKQFGKL
                     KSDKDAKPEKNLEIEQIVHVSNHEISLIKQLVDTLIADKREPNDEEVKLLRKEQRSVD
                     MALFDRMLASSPEFNVEAACQVSHALGVSAVTVESDFFTAVDDLNNKEEDAGSGHMGE
                     QGFASALFYTYVCISRDLLVENLGGNEELAKRTIAALTETALTVSPTGKQNSFASRAY
                     ATYALAEVGQKQPRSLAAAFFQPVRDTDQIPAAITRLKQQRASFDSVYGNCADDYREL
                     NVQEGTGSLAELLAFVSQ"
     gene            complement(26725..27327)
                     /gene="casB"
                     /locus_tag="OPV72_001156"
     CDS             complement(26725..27327)
                     /gene="casB"
                     /locus_tag="OPV72_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000935106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein Cse2/CasB"
                     /protein_id="HCR9913518.1"
                     /translation="MLNSNTAVLCRILHPDAQKALLDWFATLSERYERKDGKRVNGRA
                     WRAELKRMAPPYGVMICEGHDALRQALLKHMRLQPLDEMALALFVSVAVHIKSHKENI
                     SFAAQLGEKLKGSTSCVSGLRFERLQKASDPETFCQLLIQAVKIRGTEGVNVLSLADG
                     IFLWMEEWQRRENHQPEFRNPFERSRIRWANEYLSTSRGK"
     gene            complement(27344..28879)
                     /gene="casA"
                     /locus_tag="OPV72_001157"
     CDS             complement(27344..28879)
                     /gene="casA"
                     /locus_tag="OPV72_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein Cse1/CasA"
                     /protein_id="HCR9913519.1"
                     /translation="MDLTKEKWLPVIFSNGDKKKISLRDLLDNRIQDLAYPRADFQGA
                     AWQMLIGILQCTVAPEDKEEWADIWHESIEFEQWEKALNTISLALQFGEQKPSFLQSF
                     DPLDSEYGSIAGLLVDAPGGNALKLNKDHFVKRGNVEQICPHCAAIALFAIQTNSPAG
                     GAGYRVGMRGGGPLTTLVVPQEEDKYPLWKKLWLNVLPQEEPPNVTQHPLIFPWLAPT
                     KTSEKAGNVVTPDNAHPLQAYWGMPRRIELDFTHTVAGICDLCGEHHESLLLQMRSKN
                     YGVQYDSWLHPFSPYRQALKDPSAPWLAFKGQPGGLSYKDWLGLMLNREDKFNKMQPA
                     KVVRAAGQRNKMSLWCFAWDMNKAKVRCWYQHRIPLISVSHEEQFLAALNIVLVLASE
                     SLSLLRNALKSAKFDCPKEAKMDFSMVDIAFWQETEPAFRTLQEALAVDPLRQDTQTR
                     HAVSQWEAELAHYLFHVFDRDALTNPDCPDDILQRQLTARQDLASSYRKHKARKDVLA
                     LVE"
BASE COUNT         6906 a         8250 c         7385 g         6470 t
ORIGIN      
        1 ccagttctca atcgccgcat gggcatgaat aatttcttct ttatatggat tcatgatctt
       61 tcctttttca ggcacagaag cgcctgtcta ttgtttagac agacagcgta aataaggggc
      121 agcagggtga taccggcggc ggcaataaag gtccagcgat aagcaacctc aagcgacata
      181 acgcgctgga gcgcgtttaa cagcagcgtc aacagcgtcg cgccaaggaa aaagctaagc
      241 tgacgattaa gattccatag cgcgctggcg tcaggcatgt cccggcgagc aatagtcagg
      301 aaagcgccac tctgcgcggt actgctgcac aaactgccgc cagcgcccat taaggcgaat
      361 atcatcatca gtacacgatg cgatgtcgca ggcgtaacgt tagttaaaag cagtatccct
      421 gcagcctgaa gaagacagcc gacgataatc agcggacgcg gcccaagccg attgaagtaa
      481 cgtccggtaa gcataatggc gacaaatgaa gcgatcgacc aggggagcat cagcgacccc
      541 gccgccgcag gcgatagctg cgcgacgttc tgtagataaa acatcccgac cacgctgata
      601 ccaatgaaca tacccggcac acacagatag acgatcatgg caaaacgcag cagcttgtcc
      661 gtcaacaacg gcagatggag caatcttgct gacgccattg tcgtcgaagc gacgttcagc
      721 caacgataag cgagcaataa agtgagaacg gccaccggca gcgtggcaaa aaatatccag
      781 cgccagccgc acgtttccac cagcagcccg ccaatcgcag gcgaacatgc cggcgccagt
      841 agcgccacca tcatgacgac cgatgacacg ccagcgcgtt catgcggttt aaactgttgc
      901 caggttaacg cctgaccaac cgggatcaat aagccaccgc ccgccccctg cacaatacgc
      961 cagaaaacaa ggctgtgtaa ggaatcggca aaacctgcgg cagcggcggc aacgctaaac
     1021 agaatgagcg aaaatatgat cagccgtcgt gcgccgagat aacgtgaaag aaacgcgcta
     1081 aacggaacga tcagcgttaa tcctgcgata taaccgttac tcacccatgc cagcgccgat
     1141 atggacgtat gcagatccac ggacatcgca ggaaaagcca cgctggcaat aaacagatta
     1201 atcagatcaa gaaagaagcc gagcaggtaa accactgcca ctttactgcg atacgtcatt
     1261 atgcatcctc cgtcagaggc gctaatgtag ccgtccggag aaagccagat aagtccgcgc
     1321 ttcaacgata tactgtcaaa ataattttga cagtaaagga gctcgccatg ctcaatttgc
     1381 agcgtatgtc gctgtttgtc gccgtggtag atagcggcag cttcacggcg gcggccgccg
     1441 catcgggcca aacaaaagcg gtagtgagtt ttaatattcg gcagcttgaa aaagagcttg
     1501 gcgtaacgtt actgctacgt tccacccgac gactgacgct cacagacgcc ggcgtcctct
     1561 tttaccaaaa aggcgtgaat ttactcaatg cagcgaaaaa tttgcaggat gaagtgcgtg
     1621 ccagccatag tgggctgggc ggcgagttac gtattaccac tacgcccgag tttggcgaac
     1681 aggtggtcat tccggtactg gcgcagttta gtcagcgcca tcccgatctc cgtattcggc
     1741 atatgtcctc atcacatcat gccgatttaa ttgccgagcg ctttgatgtg gcgattcggc
     1801 ttggctcgct ggcggactcc cgctatcgcg ccgcgctgat atcccgcttt accattctgc
     1861 cggtcgccgc gccgcagtgg ctcgcccgcc accccgtgtc gtcactggag tcgttggccc
     1921 aggcggaatg gattattcat gagcgattac ctacgccgct acggtggaca gtaacgaata
     1981 atcatggcca acactcacgc ctggagataa gcaaagccgg caaaatttct gtcgacagcg
     2041 cgcgctcgct gatggccttc gctctcgcgg gaagcggcgt cgcattactg ccgcaatggt
     2101 tagtcaacac cgcactggag gatggaacgt taattcacgt gttacccgac tatcattttc
     2161 cccgtcaggg catttatgcc gtttatccag acgcccgcca tgtatcgaca aaagtacgcg
     2221 catttattga ttttttacgt tcgcaatggg attgcgggga gcacgcccca tcattgtagc
     2281 cagcccggga gcattgcgct cccggacgga taataccgtc ttaatcctta actaccagtt
     2341 tgtctttgat cccctgcgcc tgccaacgca cccacagcat aattgccgcc agaacgacga
     2401 ttggcagtaa cggatcgagc caactgccgc cggaaccaaa cagcaggtta atcagcgcca
     2461 cgccggtgcc gccaatcgcc caggcaatgg tcgtcggtac agaccaaacc accatctgct
     2521 gtttgacatc agagacgccc atcatgcggt taaccaccca gaacaggcta tcgttgaagt
     2581 agccgaaaaa cagcgacccc atcgttgcgg cctgagcggc aagcaacata ttgatgccgg
     2641 ggatctgcgc caggatcggc gcggaaatcg aggcggcagt gatcatcgcc accgtccccg
     2701 atccctgaat cagacgtacc agcgtcgcca cgataaacgg gatcaggatc ggcgagatcg
     2761 gcaggttggc aacctgctcc gccagctgtt gccccgcgcc gctgtcgcgc aggatcgcgc
     2821 ccaacgcgcc gccagcgccc gtgaccagta agataatccc ggcgctttgc aagccctctt
     2881 ccagacgctc tgcggtggta tgtttatcca tgcgcggcac cagcgtatac accgccagca
     2941 gaacgctgat ggccaacgcg atcactggac ttcccacaaa gttgattgcc tgtaccaccg
     3001 gatgcgtcgc caggccggac catccttcta cagtggcgag ggtggaacag atagccttca
     3061 ggaagatcag cacgatcggc accacaatag gcagcagaga gagcgtcagg ctcggcagat
     3121 ccttttgctc tttctcttta ttgtactgct ccagcgcggc attaacttca tcggcgttca
     3181 gcgtgcgcgg cacgaaatca gggtagcgtt tatccagcca ctgcgcatag aacacaatgc
     3241 cgatcacaca gggcaccgcc agcgccatcc cggtcaataa cattgcaccg atgtcgacgt
     3301 taaaaatccc ggctaccccc agcgggccgg gcgtgggagg taccgtatgg tgagtgacca
     3361 ccagcccgcc cgccagcgcg acgcccagcg tcagtagcga acgtttaccg cttttcgcca
     3421 gcgctttcgc caccggataa agaatgacaa aagcggaatc gacgaaaatg gggatgctga
     3481 caatataacc cgtgatcgcc agcgcccact cttcacggcg tttccccagc catttgataa
     3541 agctccaggc gatacgctcc gccgcgccgg aaacctccag caagcgcccc atcattacgc
     3601 cgagaccaat caccaggcca atgctgccca gcgtcgtacc gaatccgctg gtgatgacag
     3661 agagcgtttt atcaatgccc attcccccca acagaccggc gatgcaggcc gccgccagca
     3721 tcgcgatcag cgcatgaaca cgggtgcgta acaccagcca taccagcacg aaaacggcaa
     3781 cgatcaggcc gataattggg gtcggtaaac ttgtcatgac ctcccctcca tatcatcttg
     3841 tcgaaagcgt tcgataatgt catcgaagcg tttatcggcg acaaaaccta acgccagcgc
     3901 acgctggtta tcgatacgtc ccggccagga ggcgacaatt ttctcgacgc cttcgtcgcg
     3961 ctgatgcgta acccgatcgc gcgccgcctg accgcccgcc tgacgcaacg tttccagcat
     4021 ctcgcccacg gttacgctga tcccgggtaa gttgatgctg ctcgcctcgc caggcgcggg
     4081 taacgttgcg gccagcgaca ggttatggat caccgtcgcc gggctggaaa tccacagccg
     4141 caaactttcc gacaccggac agatggtcgt ctcgccctgc aacggttcac gaataatcgc
     4201 gctgacaaaa gaagaagcgg cgcggtttag tttacccggg cgaacacaga tcgtcggcaa
     4261 acgcagcgcc agcccatcca catagccttt gcgggtatag tcgttgacca acagttcaca
     4321 ggcggccttc tgcgcgccat aagacgagcg cggcgtgagc gcggtggtat cggtgacgca
     4381 ttccggcagc gtaccgccat aaacggcaag cgagctggag aagacaaaac gaattttctg
     4441 cggttgccga cgacacgcct caagtaactg gcgggtaaga tccaggttaa ctttccatcc
     4501 cagatcgaaa tcgtcttccg catgactgct gacaatcgca gcgagatgat aaacaacaga
     4561 ggtattagcg gtaatcacat tctccagtac gcccggctgg gttaagtcag cttccaggca
     4621 gcgtaaacga ggggaatctg ataaccgtgc aggcattttt aaatcaacaa gaagcagttc
     4681 gttaaacgcc agcgatgagt ttaataaggc gcttgcgagt ttctggccta aaaagccgcc
     4741 cccgccggta atgataatct gcatccggat gtcctcttta ttgttgtgta gggtagttca
     4801 gggttagcgc caggcgttaa accagccaag cccctcctga gtggtattcc gtggttggta
     4861 ttcgcagcct atccagccgc aataacctac gtcatcgaac agccggaaca gccacgggta
     4921 gttgatctcg ccatcatccg gttcatgtct gtccggtagc gaggcgattt gtacatgggc
     4981 atagcggccc gcgtactcgc gaatcaggtg actcaaattg ccatccactt tttgcgcgtg
     5041 gaaagtgtcg agctggatga atacatttgg gcggtcaacc tcttctgcga tgcccagcgc
     5101 ctgatattgg ctggaaaaga ggtagccggg tttaacgccg ggactcagcg cttcgatcaa
     5161 aatacgttta tcgtgggcgg caaaccggcc ggcggcataa cgcaaattat cgataaacgt
     5221 ggcgcgataa cgtgcgccat cagcgccatc cggcacgacg cccgccatga tgtgaacctg
     5281 ctcgcattcc agcgccagag cgtattccag agccagatca atatcggcgc gcgcgtcgtg
     5341 ttcgcgcccc ggtagcgcgg cacgtcccca ctcgcccgcc gcggtatcac ccgccgaagt
     5401 attaaacagc gccagcgtca gatcatgacg cgatagctgg gctttaatct cgctggcggc
     5461 aaagccgtag gggaacagaa actcaacggc ctgaaaaccg gcttcggcag cagcggcaaa
     5521 acgctcgata aacggcactt cggtaaacat catcgacaaa tcggcggcaa aacgcggcat
     5581 cgggttatct ccttaactgc gcaatttctt cggtggttaa ataacgaatc gggcgttcgc
     5641 caaggataaa aatcagcttt gccgtctctt ccagctcctc ggtattatta gcggcttcct
     5701 gcaaattctc cccgcacacg accggcccat gattagccag taaaaaggcc tgatgccggg
     5761 ccgccagcgc agccaaatcg cgagcaattc ggtcatcccc cgggcgatag tagggaacca
     5821 gcggaatgtc tcccatccgc atcaccacat agggggtaaa cgggcgaatc acattttgcg
     5881 ggtccagccc ttcgagacag gaaagcgccg ttgaccaggt gctgtgcaga tgtaccacgg
     5941 ccttgcagca agggttattg cgatacaacg ccagatgaaa acgcacctct ttagacggtt
     6001 tatcgccgct gagccattcg ccttgcgggt ccactttgga tagccgctgc gggtcgagat
     6061 tacccagaca cgaaccggtg ggcgtcgcca gaatattgcc gtccggcagt aacagcgaga
     6121 ggttgcctgc cgagccggtg gcatagccgc gctggaaaaa cgaggcggct atcctgacca
     6181 tctcttctcg caaagcgtgc tcttcttttg ccagtatcgt catacctgaa actccctttg
     6241 agcgcggatg aaaaaggatt catcgccaaa attacctgac tttagcgcca gcgagactgg
     6301 cgcatggagc gcgttgaccc acggcacgcc gggtgaaatg cacggtccaa tgtggaaacc
     6361 ggtaataccg aggctttgcg tcaccacgcc cgaggtttcg ccgcccgcca caataaaccg
     6421 ggtgataccg ccttccgcta agcgagcggc cagcagggaa aagagcgcct ctaccgcata
     6481 gctggcttcg gtagcgccat attgctgctg gatggcagcc agcgcctgcg tggaggcggt
     6541 ggcgctaatc attggcgcca gttcgctgtc ctgactgaac acccactgcg ccagcgcttc
     6601 ggcgtaggcc tcgcgcgcct cggatgacag gcagcgcgcc acgtcaacgt cgcgtgtggg
     6661 agcatgttgt cgatagaaag ccacctgctg attcgtcatt tgcgaacagg aaccggaaag
     6721 cactaccgcg cgaccgctca gcggatagcc tgcggaacgg gcctgagaaa cgccgtgctt
     6781 cgcccactga cgcgccagcc ccattgccag cccggaaccg ccggtcacca gcggggcatc
     6841 acgcaaaacc tcgccctgga tttccaggtg ccgctcattg agcgcgtcaa gtaccgcgta
     6901 gcgatatcct tcctgctgta aacgcgacag cgccgcacgg gtcgcggcaa cgccttcatc
     6961 aagcgtctga gccggaataa cgccgcagcg cccttgcgcc tgcgcccggt gtatcgctga
     7021 tgcgataaac gttgctggca acggcgtcca gcacaggctt caggcgggta aacgccgcct
     7081 cgcgcccgga ggccatcacc gtccgccctg cgccgctttt accgcgccgc cggaaaccgg
     7141 cgcatccagc atgttaagat tcaatgccgt caacgccgcg gcgatctctt gcgcgtcggc
     7201 gcttgagatc gtagacgaaa ccatcaccgc gcttccgggt ttcatcagat gggcgacgcc
     7261 atcctcaccg aataacacct gtctgacctg ggcggcattg acgaccagaa tgactaacgc
     7321 atccacgacg ccggcgaact ccctggcgct ggcggcagcc ccacaagccc cttcagcgag
     7381 cagattcgcg cacgcttgcg ggttaagatc ggccccccat gtggaaagcc cggcgcgcag
     7441 gcatgaacgc gcagcgccca ttcccattga gccaagcccc acaatgccga catgaaaatc
     7501 agttcctgtt gtcattatca ctccatgtta atttacgtga tattatgttt tgttatgtga
     7561 atataggcgt ttttgtaaac aattgcggtg agttgtttca caaaaaataa caaaatatgt
     7621 tattttttgt gaaggcaatc ctcatagaac ttcacacgct gtgacgagaa atcgcgtaaa
     7681 atcgcgacag gactaaagaa aggagcagac gttgatacct actgagcgtc gacaaatcat
     7741 tcttgatatg gtggcggaga aaggcatcgt cagtatcgct gaactgaccg agcgcatgca
     7801 tgtatcccac atgactatcc gccgtgattt acaaaaactg gagcagcaag gcgcggtaat
     7861 ccaggtctct ggcggcgtgc aatcatcgac tcgcgtggcg cacgaaccct cgcatcagat
     7921 caaaaccgaa ctggcgacgc cgcagaaagc ggcgattggc aaactggccg ccagcctggt
     7981 acagccagaa agctgtatct accttgatgc aggtacgacc acgctggcga tcgccaggca
     8041 gctggttacg atgaataaac ttacggtggt gaccaatgat ttcgttatcg ccgattacct
     8101 gatggacaat agcggttgca caattattca cactggcggg gcggtatgcc gggaaaaccg
     8161 gtcgtgcgtc ggtgaagccg cggcgacgct tttgcgcggg ctgatgattg accaggcctt
     8221 tatttccgcc tcttcctgga gcgtgcgcgg tatttcaacg ccggcagaag ataaagtcac
     8281 ggtgaaacgg gccgtcgcca gcgccagccg ccaaaaaatt ctggtgtgcg acgcgaccaa
     8341 atacggccag gtcgcgacgt ggctggcgtt atcgctggcg gaattcaacc aaatcgtcac
     8401 cgatgacggc ctgccggaaa gcgcaattcg ggcgctggct aaagtggata tctcactgct
     8461 gatggccaaa caatagcgaa gcggcgcaag ccgcttacgt catcatcttg cgaaccagtt
     8521 gcgtaaactg ttcgcgttct tcagcgctca gtcgccccaa aaactcatcg tcaacgcgat
     8581 cccccagtgg tatcgcggcg gcgagcaacg tttggccctg aacggtgaga tagacaaaac
     8641 gccgacgttt atccagcgga tcgttttctc gctttaccag cccacgattt tccatccggc
     8701 ttaacatctc cgccagcgtc gctttagtgc tgaccgccgc ttcggtcaga tcgacctgtt
     8761 caatacccgg atgttcagca ataacgcgca tcaccgcata ttgaggtttg gtgagctccg
     8821 gtagttcatg ctgccagcgt gcggtatgtt gctgaaaaag ttggcgtaac agatgaaacg
     8881 cggtgtttcg taactccatg agcgctccgg ataaattaac tttttctatc ataacgactt
     8941 atgcacggtt ttttaatgac gaatgcttta gctaaacgtg cgcaggcatc gggagcgatc
     9001 ttgtcgcaaa ggccgtgtgg gcgtattttg atcaaaatgt tcgtatacga acgatatttg
     9061 aggtaagaaa tgagattgat tgtggggatg accggtgcga ccggcgcgcc gcttggcgtc
     9121 gagctactcc aggcattgcg ggcgatacct gatgttgaaa cgcatctggt aatgtcaaag
     9181 tgggcgaaaa ccactattga actggagacg ccctacacgc ccgctgaggt agccgccctg
     9241 gcagattatt gtcatagccc ggccgatcag gcggcgacca tttcctccgg ctcatttcgt
     9301 accgacggca tgattattat cccctgcagt atgaaaacac tggcgggggt tcgcgccggc
     9361 tatgccgatg ggctggtggg acgcgctgcc gatgtcgtgt tgaaagaggg tcgcaagctg
     9421 gtgcttgtgc cgcgggaaat gccgctcagc acaattcatc tggaaaacat gcttgcgctt
     9481 tctcgtatgg gggtggcgat agtgccgccc atgcccgcgt tctacaacct gccgcaaacc
     9541 gttgacgata ttatccagca catcgtggcg cgcgttctcg accagtttgg tctggagcat
     9601 acgcgcgcgc gccgctggca aggactgcga caggcagcaa atttttcaca ggagaatgga
     9661 taatggcatt tgatgatttg cgcagttttt tacatgcgct ggatcagcag ggacaactgc
     9721 tgaaaatcag cgaggaagtg aatgcggagc cggatctcgc cgccgctgcc aacgcaacgg
     9781 gacgaatcgg cgatggcgcg cccgcgctgt ggtttgacaa tattcgtggt tttaccgacg
     9841 cccgcgtggc gatgaatacc atcggttcct ggcagaacca tgccatctct ctgggtttgc
     9901 cgcctaacac gccggttaaa aaacagatcg atgaatttat tcgccgctgg gacaattttc
     9961 cggtagcgcc ggaacgacgg gcgaatccgg gctgggcgga aaataccgtc gacggcgacg
    10021 cgatcaacct gtttgatatc ctgccgctgt ttcgtctgaa cgacggcgac ggcggattct
    10081 atctggataa agcctgtgtg gtatcacgcg atccgctcga tcccgataac ttcggcaagc
    10141 agaatgtcgg catctaccgt atggaagtta aaggcaagcg taagctgggt ctgcaaccag
    10201 tgccgatgca tgatatcgca ttgcacctgc acaaagccga agagcgcggg gaagatctgc
    10261 cgattgcgat cacgttgggt aacgatccga tcattaccct gatgggcgca acgccgctga
    10321 aatacgatca gtcagagtat gaaatggcag gcgcgctgcg tgaaagcccc tatcctatcg
    10381 ccaccgcgcc gctgaccggt tttgatgtac cgtggggatc tgaagtcatt cttgaagggg
    10441 tcatcgaaag ccgtaaacgt gaaattgaag ggccgttcgg cgaatttacc ggccactatt
    10501 ccggcggtcg caacatgacc gtggtgcgta tcgataaggt ctcttaccac agcaaaccca
    10561 tttttgaatc gctctatttg gggatgccgt ggacggaaat cgactacctg atggggccgg
    10621 cgacctgtgt gccactgtat caacagctga aagccgaatt tccggaagtg caggcggtaa
    10681 acgctatgta cacccacggc ttgctggcca tcatctcgac caaaaaacgc tacggcggct
    10741 ttgcccgtgc ggtgggcctg cgcgcgatga cgacgccgca cggtctggga tatgtgaaga
    10801 tggtgatcat ggttgatgaa gatgtcgatc catttaatct gccacaggtg atgtgggcgt
    10861 tgtcgtcgaa agtgaatccg gcaggcgatc tggtacagct accgaatatg tccgtcctgg
    10921 aactggaccc gggttcaagc ccggcgggga ttaccgacaa actgatcatt gacgctacca
    10981 cgccggttgc gccagataac cgtggtcact atagccagcc ggttgtggat ttaccggaaa
    11041 ctaaagcctg ggctgaaaag ctgaccgcca tgctggccaa ccgtaaataa ggagtaaccg
    11101 atgatttgtc cacgctgtgc cgatgcacat attgaactca tggcgacttc gccggtaaaa
    11161 ggagtctgga cggtatatca gtgtcagcat tgtctgtata cctggcgcga taccgaaccg
    11221 ttacgccgta ccagccgcga acactatcca caagcgtttc gcatgacgca aaaagatatt
    11281 gatgacgcgc caatggtgcc gagtatcccg ccgttgctgg cagaagacaa acggtaaaaa
    11341 aaaggccagt ctgtcgactg gccttttttt gacaagggta cttactcgcg gaacagcgct
    11401 tcgatattca gcccctgcgt ctgcagaatt tcgcgcagac ggcgcaggcc ttcaacctga
    11461 atctgacgaa cacgttcacg cgtaagaccg atttcacggc ctacatcttc cagtgtcgca
    11521 gcttcatatc ccagcagacc gaaacggcgc gccagcactt cacgctgttt ggcgttcagt
    11581 tcgaacaacc atttgacgat gctctgtttc atatcgtcat cttgcgtggt gtcttccgga
    11641 ccgttctctt tttcatcggc caggatgtcc agcaacgctt tttcggaatc accgcccagc
    11701 ggggtgtcta ccgaggtaat gcgctcgttg agacgaagca tacggctgac gtcatcaacc
    11761 ggtttatcca gttgctctgc aatttcttcc gcactcggtt cgtggtccag tttatgcgac
    11821 aactcacgtg cggtgcgcag gtatacgttc agctctttaa caatgtgaat cggcaagcga
    11881 atcgtacggg tttggttcat aatcgcccgt tcgattgtct ggcgaatcca ccaggttgcg
    11941 tatgttgaga agcggaaccc gcgttccggg tcaaacttct cgactgcacg gataagcccc
    12001 aggttgccct cttcaatcag gtccagcaac gccagtccac gattgccata acggcgggca
    12061 atttttacca ccagacgcag gttactctca atcatgcgac ggcgagaagc gacatctcca
    12121 cgcagtgcgc gacgcgcaaa atagacttct tcttcggctg ttaacagtgg tgaataccca
    12181 atctcaccaa ggtaaagctg agtcgcgtcc aacacacgct gtgtggcccc ttgcgataac
    12241 agctcttctt cagccaggtc gttatcactg ggttcctctt cactcaaggc tttttcgtca
    12301 aaagcctcta ctccgttctc atcaaattcc gcgtcttcat ttaaatcatg aactttcagc
    12361 gtattctgac tcataaggtg gctcctaccc gtgatccctt gacggaacta gcaagtcaaa
    12421 gcctggttcc gccgctttat cgctgcggta aataacgcag cgggtttacg gatttcccct
    12481 tgtaacgaat ttcaaaatgc aagcgtgtag agctggtgcc ggtgctaccc atagtagcga
    12541 ttttttgccc cgccttaact tcctgttgtt cccggaccag catcgtatca ttatgggcgt
    12601 aggcactcag gtaatcatcg ttatgtttga tgataataag attaccgtaa ccacgcagtg
    12661 cgttaccggc atatacgacg cgcccatcag cggttgcgac gatagcctgt cccttactgc
    12721 ctgcaatgtc gatcccttta ttgccccctt cggaagcgcc aaagttttcg atcactttgc
    12781 catccgtcgg ccagcgccat gcggaaatcg gcgcgctggt tgacgtactg cttgcatttg
    12841 gttcggtcgt gcttaccgtt ggtgccgtta caggcgctgt gacaaccgtc ccagcaggct
    12901 tgttgtttgg caacattttg ttagcacttt gttcacctga gccctcagaa tacgtaattg
    12961 ttggttgaga cgcaactgca acggtggaat tttgtgcaga cctggtcaca actccttgct
    13021 gtgctgcatc cgcctgggtg atcgcatttc cgccagtaat tggcgtaccg gatgcgttac
    13081 caacttgcaa agtttgccct acattcaggc tatacggggc agaaatactg tttctctggg
    13141 ccagatcgcg gaaatcattc ccggtaatcc aggcgatgta aaaaagcgta tcaccctttt
    13201 tcacggtgta agtactgccg cccgtatagc tacctttcgg aatattccca tactggcgat
    13261 tgtatacgat tcgcccattt tccatctgca cgggttgttc cgtgaccggt tgagtttgca
    13321 tgggctgcgt tacaggacgc tgaacgggtt gaatttgcgg cgcttgttgc ggcgtcgcgc
    13381 ccatttttgg cggcggtgtg atcaacatcc cggaattggt atttgatgac gacccactgt
    13441 ccacagacgt gaccggcgcc ggagggtttg acgaactggt acaacctgcc agccatagtg
    13501 aaaccagtga tagtgccgca atgcgactaa cggtgaattt tgggcttccc gcgctcattt
    13561 atcccccagg aaaaaatttg gttaacaacc agtgacgtaa gaaccgtgca acgcattaag
    13621 tgaacacggg aaaatgtgtt cacgatacgc ttaacccacc gggaataacc aggaaaactc
    13681 caggtattcg tttcggcttc atcaggcgta atagtggctg tttgcagggc aaactaggcc
    13741 agctctccct tgactaacgg gacgaagcga acggcctcca cggtatcgat aataaattcg
    13801 ccgccccggc gacgcacgcg tttcaaaaac tgctgctcat cgcccacagg cagaacaaga
    13861 atgccgcctt catccaactg tgccatgagc gcggtaggaa tttccggcgg cgcggccgtc
    13921 acaatgatag cgtcaaacgg cgcacgcgcc tgccagcctt gccagccatc gccatgacgg
    13981 gtagaaacat tatgtaaatc gagctgcttc aggcggcggc gcgcctgcca ttgcagcccc
    14041 ttaatccgct caacggagca aacgtgatgt accagatgcg ctagaatcgc cgtctgatag
    14101 ccggaaccgg tgccaatttc caacaccctg gattgcggcg tcagttcgag cagttccgtc
    14161 attcgcgcca ccatataggg ctgcgaaatc gtctgaccct ggcctatcgg caaagcgata
    14221 ttttcccagg ccttatgttc aaacgcttca tcaataaatt tctcgcgcgg cactgcggca
    14281 agcgcattaa gcaccagctc atctctgatg ccctgcgcgc gcaattgttc aagaagagcc
    14341 tgtacacgtc cacttaccat tgcgtgccaa ctcccacgct gtctaaccag tctgaaacca
    14401 catcatgcgc gctgtgcgcg gttaaatcca catgcaacgg cgtgacggag acgtagcctt
    14461 catccaccgc cgcgaaatcg gtatccggcc cggcatcgta tttatcaccc ggcgggccaa
    14521 tccagtacaa tgtattaccg cgtggatctt cctgcgggat cactttatcc gctggatggc
    14581 ggctaccgca gcgagtcacg cggatgcctt taacctgcgc taacggtaga tccgggacat
    14641 tcacgttgag aatacgcccg gtacgcaacg gctcccggct taaccctcgc aaaagcgcgc
    14701 aagtcacggc tgcagccgta tcataatgct gatagccgtt aagggagacc gctaatgccg
    14761 gaaagccgag atgacgacct tccatcgccg cggcgacagt accggaatag atcacatcat
    14821 cgcccagatt cggacccgcg ttaataccgg aaacgacaat atccggacgc ggacgcatta
    14881 aggcattaac gcccagatag acgcaatcgg tcggcgtccc catctgtaca gcgatatcgc
    14941 cattatcaaa ggtaaaagta cgaagcgaag attccagcgt gagggaatta gacgcgccgc
    15001 tgcggttacg atccggggct acgacctgta catcagcaaa ctcacgcagc gctttcgcca
    15061 gcgtttgtat accgggcgcg tgaaccccgt catcgttact cagcaatatg cgcataatca
    15121 cccattgtgt tgatcagttc ccttactacg ctggtggcaa aactgcctgc gggcagccag
    15181 aaacgtaact cgacggtaac gtcatcccac cagttccagc ttaattgttg cggataaagc
    15241 agcatcgctc tgcgcgacgc ctctactttt tcgcgcagca acagcgattg caacaccgtt
    15301 tcctgggcaa tggcatcttg ctcaaacgcc agcgccgcac gctgtgttcc ccactctccg
    15361 ctgcccggca acgacgctgt aatcatcagc tctttttcgt ctacccggcg ctgcaattca
    15421 ggcagttctt cagatgtcgc gacgaaccag cttccacgcc ccgctaattg tagcgcatcg
    15481 ccgtcaacaa cttgattaaa gtctggtttc ttcagccgct ggtgaacaat ttgattaaac
    15541 aacgcgctac gcgccgccga caaccaaaaa ctgcgtttat tgcgatcgcg caccggcgcg
    15601 ttactttgcg cccagcgcag cgcgccctgc aagttgctgc cgccaatgcc gaatcgttgt
    15661 gcgccaaaat agttcggcac gccgccatcg cgaatcgcct gcaatcgtgt ttcgacatcg
    15721 cggcgatcgc ttatttcacg caataccagc gtaaaggcat tgcctttcag cgcgcctaaa
    15781 cgcagcttac gcttgtgacg cgcgtattcc agtactttac aaccttccag ctgaaaggcg
    15841 ctgaaatcgg gcatctcttt ccccggcacg cgcgcgcaca gccactgctc ggtaacggcg
    15901 tgtttatctt tttgcccggc aaagctcact tcgcgagcgt gaattttcag gaatttcgcc
    15961 agcacgtcag cgacaaaacg ggtattgcaa ccgtttttca aaatacgcag cagaatgtgc
    16021 tcgccttcac catccggcgt aaagcctaaa tcttcaacca ccacaaaatc ttccggattc
    16081 gctttcagca atccgctacc ttgtggtttt ccgtgcagcc aggtgagatt gtcaaactct
    16141 gtcatttcgc cgccttcatc agcaacgcca ccgcttcgca ggcaatgcct tctccgcgtc
    16201 cggtaaatcc gagcttttcc gtcgtcgtcg ccttcacgtt aacatcatcc atatggcagc
    16261 cgagatcttc ggcgataaag acgcgcattt gcggaatatg cggcagcatt ttcggcgcct
    16321 gcgcaataat ggtgacatcc acgttgccga gggtgtatcc cttggcctga atacgacgcc
    16381 aggcttcacg cagtagttcg cggctatccg ctcccttaaa tgccggatcg gtatccggga
    16441 agagcttgcc gatatcgcca agcgccgccg cgcccagcag cgcatcggtc agcgcatgta
    16501 acgccacatc gccatcggaa tgcgccaata gccctttttc ataagggata cgcacgccgc
    16561 caataataat cggcccttct ccgccaaacg cgtgtacgtc aaaaccgtgt ccaattcgca
    16621 ttatgctttc tcctggtgga tggttcgggt cagataaaat tccgccagcg ccagatcttc
    16681 cggacgggtg accttgatgt tatccgcgcg accttctacc agcgccggat gaaaaccaca
    16741 atactccagc gctgacgcct cgtcggtgat ggtcgcgcct tcattcagcg cacgcgtcag
    16801 acaatcgtgc aagagttcgc gggggaaaaa ctgcggggtg agcgcgtgcc ataaatcggc
    16861 gcgctctacg gtatgggcaa tagcgttttt ccccggttcg ccgcgtttca tggtgtcgcg
    16921 caccggactg gcgagaatac cgccgacccg gctgttttcg ctgatggcca gtaaccgcgc
    16981 aaggtcatcc tgatgcaaac agggtcttgc cgcgtcgtgc accagcaccc actgcgcctt
    17041 tgcaacggcc tgtaacccgg ccaaaacgga atcagcgcgt tcgttgccgc catccacaac
    17101 ggtgatttgc ggatgattcg ccagcggaag ttgggcaaag cgatgatcgc cagggctgat
    17161 agcaataaca acgcgtgtca cccgaggatg cgccagcagc gcatgaactg agtgctccag
    17221 aatggtttta ttaccgattg agagatactg cttaggacat tctgtttgca ttcggcggcc
    17281 aaatccggcc gccggcacca cggcgcaaac gtccaataaa gtggctgcca tgttaaatcc
    17341 ctggatggtt tatcgatgag tttgccccgc cgttgccgcg cgttttgagg cgtcaggcac
    17401 cagacgatag aaggtttcgc ccggtttggt catgctaagt tcgttgcgcg cgcgctcctc
    17461 aatcgcttcc tggccgccat tgagatcgtc aatttcggca aaaagctgat cgttacgcgc
    17521 tttaagtttg gcgtttgtcg cctgctgcgc gaccacatca tcgttgacgc ggctatagtc
    17581 atgtatgccg ttcttaccga accacagcga gtactgtagc cagaccagta aagccagcaa
    17641 cagcagcgtt agtttaccca tcctgccccc tgaaaaacgg catcatcatc ccataacgtc
    17701 ctctgtgact ccacattcag gacgggattg ccgcgacaac gccggcaaat gtaccacatt
    17761 tgccggatgt tacgtatacc cgagtaagga gaacataatc tcattgttgg ttacggtttg
    17821 aattatgacc ggaggcgcag tgataacccg tctaccctaa tagccatatg aataacgcgc
    17881 cgaacagcgc gcctacggcc agtagagtaa acatgatgct aaaaagtatt ttgcccttta
    17941 ccaacagatg caacgcaatg ccgataatca ccgataccgg cattaacgcg aggaaaaagg
    18001 gccaagtata gaggaaaaaa aacagcgtgt tagggccata aagcagaaaa gggatcccca
    18061 acgccagcag ccatgacaca aagccgacca ccgcccccgg aaatgcactg gtggcgtcat
    18121 cgtcgaccat gaaggcgtct gaccttgtga aagtaatgtt atggctatta cgcatattaa
    18181 atcctgtaac cttgaccata ccgggcatac aagcccggtg gtgtctcagg atctgataat
    18241 atcgcgccgt ctcagcaggt ctaataattg ggaaaccaaa tttgttacta attgttcacc
    18301 attaagatga acctggggcg agtcaggcgc ttcgtaaatg gcgtcgatac cggtaaagtt
    18361 acgcaactcg cccgcgcgcg cttttttata caatccttta ggatcgcgct gttcacagat
    18421 agccagcggc gtattgacat aaatctcgat aaaacgatcg tggccgacgc gctcttttac
    18481 cagttgccgc tcggcgcggt gcggagaaat aaatgccgtc aaaacaatca ggccagcgtc
    18541 cgccatcaga ctggccactt cgcctacccg ccgaatattt tcctggcgat cggcatcgct
    18601 aaagcctaaa tcacggcaca aaccgtggcg cacattatcg ccatccaaca ggtaggtact
    18661 gacgccacgc tgatgtaacg cctcttccag cgcgccggcc accgttgatt ttcccgaacc
    18721 ggagagtccg gtaaaccaca gcaccacgcc acggtggccg tggagctgtt cacgagcggc
    18781 gacagtaacg ggatgagagt gccagaccac gttctcatca tgcagcgcca tgtttatctc
    18841 ccagcaaatc tcgggcgtcc cagtgcggaa aatgacggcg taccagcgca ttcagctcca
    18901 gctcaaacgc actgtattcc acgggcggcg tcgctccgcg ttcatccagt tcccgcacca
    18961 tgccagcacc cacggtaacg ttagaaagtc ggtcgataaa aatcagcccg cccgtcaccg
    19021 gattttgctg ataaatatcc agcgcgagcg gctcatcgaa tgtcatctct accagaccaa
    19081 taccgtttaa cggcaggctc tcgacgtctc gttgagtcag attgttgata tcaatctgat
    19141 agcaaatagc ctcgatacgc gcgcgggttt tcttacccgc aagtttaacg tcgtagcttt
    19201 ggcccggcgc cagcggctgt tccgccatcc ataccacatc gatcgcggcg tgccgcgcag
    19261 gtgccagcgt ctcgtttgcc gccagcagca gatcgccgcg gctaatatca atgtcgtcgt
    19321 tgagtaccag ggtaatggct tcgcccgcac agacttcttc tttgtcgcca tcaaaagtga
    19381 cgatacgcgc cacgctggat tccacgccgg acggcagcac tttaatgcgc tctccgactt
    19441 tgacgctacc agacgccaga gtgccggcat acccccgaaa atcagggttc gggcgattga
    19501 cgtattgtac tggaaagcgc atcggctgac ggtctaccgc acgctgtatg tctaccgttt
    19561 ccaggacttc caacagcgtc gggccgctgt accagcgcat attggcgctc tgcgcggcga
    19621 cattatcccc ttccaacgcc gaaagcggga caaagcgaat gtccagatcg cccggcaact
    19681 gttcagcaaa ggtcaggtaa tcttcgcgaa tacgggcgaa ggtctcttcg cggtagtcaa
    19741 cgagatccat tttgttgatt gccaccacca ggtgtttgat ccccaacaga gtggagataa
    19801 agctatggcg acgcgtctga tccagcacgc ctttacgcgc gtcgatcagt aggatcgcca
    19861 gatcgcaggt ggacgctccg gtcgccatat tacgggtata ttgttcatgg cccggcgtgt
    19921 cggcgataat aaattttcgt ttttccgtgg agaaatagcg gtacgcgacg tcaatagtaa
    19981 tgccctgctc acgctcggcc tgcagcccat ctaccagcag cgccagatcg agtttttctc
    20041 cctgcgtgcc atgacgttta ctgtcattat gcagagaaga gagctgatct tcataaattt
    20101 gcagggtatc gtgcagcaaa cgacctatca gcgtactttt accgtcatca acgctgccac
    20161 aggttaaaaa acgcagcagg cttttgtgtt gttgggcaat catccaggct tcgacgccgc
    20221 cttcactggc gatttgttgt gcaagtatgg tgttcatggc ggctccttag aaatacccct
    20281 gacgtttttt aagctccatc gaccccgcct gatcgcggtc aatcatcctc ccctggcgct
    20341 cgctggtggt agaaaccagc atctcttcga taatttccgg cagcgtttgc gcgtgggatt
    20401 ccaccgcccc ggtgagcggc caacagccaa gtgtacggaa gcgcaccatc ctttttttga
    20461 tgacttcgcc aggttggagg tcgatacgat cgtcatccac catcatcaac atgccatcac
    20521 gttccagaac cgggcgttca gcagccaaat acagcggcac gatgtcgatg ttttccagcc
    20581 agatgtattg ccagatatcc tgctctgtcc agttggagag cgggaagacg cgtatacttt
    20641 cgcctttatt aatctgaccg ttatagttac gccacaactc tggccgctga tttttcgggt
    20701 cccagcgatg gaaacggtca cgaaaggagt aaatacgttc tttcgcgcgg gatttttcct
    20761 catcgcgccg tgcgccgccg aacgcggcat caaaaccgta cttattcagc gcctgcttta
    20821 acccttcggt tttcataatg tcagtgtgtt tagcgctacc gtgaacgaac ggattgatgc
    20881 ccatcgccac gccttctgga tttttatgta ccagcaattc gcagccgtat gcgttggcgg
    20941 tacgatcgcg aaaggcgtac atctcacgga atttccaacc ggtatcaacg tgcaatagcg
    21001 ggaacggtaa cgtacccgga taaaacgcct tacgcgccag atgcagcatg acgctggagt
    21061 ctttaccaat ggagtacagc atgaccggat tagcgaattc cgctgctact tcacggataa
    21121 tgtggatact ttccgcctcc agttgccgca ggtgggtgag tcgtttttga tccataaccg
    21181 ttcctttgca ataccgtttt ttgctaaaca tttcgattac acgactatag ggagcgcggg
    21241 agagtgaatg aaatgacgaa ttggaatgag tagttcctca aaggaataac gcggcccaaa
    21301 aaccaatatc aaaaaatgct taacgtaccg gattgccagc atttaggagc aaatgaaatt
    21361 gtattaacac gatcgcggtt tcatactagc cccgtaaaat tttgttctgt atttaaggac
    21421 tcattatgtt ttccgcaacg cgccgctttg ccgtcattct ggcgctcggc gtaggcttta
    21481 tccttcctgc acaagcagca tcaccagggc ctggtgaaat agcgaatact caggcacgac
    21541 atatcgccac cttttttccc gggagaatga ctggctcccc cgccgagatg ttgtctgccg
    21601 attatttacg ccaacaattt acccagatgg gataccaaag cgatattcga acgtttaata
    21661 gccgatttat ttataccacg aaggataatc gcaaaaactg gcataacgtg acgggcagta
    21721 cggtcatcgc cgcccatgaa gggcgcgtgc cgcagcagat catcattatg gcgcatctgg
    21781 atacctacgc tccgcagagc gatgctgatg tcgatgccaa tctgggcggt ttaacgttac
    21841 agggaatgga tgataatgcc gcgggattag gcgttatgct ggaactggcg gcgcgtctga
    21901 aagatatacc gacccattat gggattcgtt ttatcgccac cagcggggaa gaagagggaa
    21961 agctaggcgc ggaaaattta ctcaaacgaa tgagtgacgc tgagaagaaa aatacgctgc
    22021 tggtgattaa tctcaataac ctgattgttg gggacaagct ctattttaat agcgggaaaa
    22081 atacgccgga agcggtgcgt acactgaccc gcgatcgggc attagcgatt gcgcgccgtt
    22141 atggcatcgc cgccaacacc aatccgggac gcaatccatc ctaccccaaa ggaacgggtt
    22201 gctgtaatga tgcggaggtt ttcgataaag cgggaatatc ggtgctttct gttgaggcga
    22261 cgaactggaa tctgggtaaa aaagacggat accagcaacg tgtgaaaaat gcatccttcc
    22321 cgaacggcaa tagctggcac gacgtacggc ttgataatca acagcatata gacaaggcgc
    22381 tgccagggcg gattgagcgc cgtagccgcg atgtagtgcg gataatgctg ccgttggtaa
    22441 aagagctggc gaaggcggaa aaaacgtcct gatatgctgg tgaaacgtgt ttatccccgc
    22501 tggcgcgggg aacacggaca gcaacccgtg tcggatatca gacagatcgg tttatccccg
    22561 ctggcgcggg gaacacacgc gaatcgccaa tcgccgccgc gtgaattgcg gtttatcccc
    22621 gctggcgcgg ggaacaccca cgatgtatgc cgaccgtgat ttttaccgcc ggtttatccc
    22681 cgctggcgcg gggaacacag atacgccttt acgtcgccct ctttggcgcg cggtttatcc
    22741 ccgctggcgc ggggaacaca ttaaaaaaga ttaatgttgg ttatagtttt acggtttatc
    22801 cccgctggtg cggggaacac taaaacaccg gttgcgcaac ctccgcgggg atcggtttat
    22861 ccccgctggc gcggggatcg gtttatcccc gctggcgcgg ggaacactct aaatctaccc
    22921 aattgaattt aaatactttt ttagcgcaca aaaaacccac caacttttcc taatttttaa
    22981 agatctctaa cttattgatt ttcaacaggt agaaacgaca ccaatcgcag tccatcaaga
    23041 tctaccggaa tacgtcgatt tacaccaaaa gtctgaaact caaaacctga ttctgtattt
    23101 gtcgcccacg ccataacaac atttccctca tctgccagaa cggaaacctg ttgccatatc
    23161 atctcgcgga tctttgcgga aacatcacca acatacacac cagctcgaat ttccagtaac
    23221 cagacggcca gcctcccccg cagacgagga ggaacatttt cggtaacgac aaccagcata
    23281 ctcatcgtta ggtactccga tgaccggaat ctcccaacgc aacaggaaga gggatcgcta
    23341 tggggtgtga atcttcagga ggtaacggcg gttgaatttc ccctgccgcg agaacatctt
    23401 caataagagg aatcaatttc gccaatgttt ttccactgcg gaagatatcc cggcaggcaa
    23461 tacggacatc acgatcgggc tcggcaggat tacgtcgcgc aatttcaaat gctttcggta
    23521 caacgatctc aaatttaatg atatcggcaa tatcatagac aaaagaaagc ggcttgccgg
    23581 tgtgcacaaa tccaatcgcg ggcgcatatc cggcagccag tattgccgcc tccgttacgc
    23641 catagaggca ggaggttgcc gagctgatac actgattaat gacatcgcct ttctcccagt
    23701 ctttcggatc gtagcgacgt ccctgccatt tcacgccata ctgcttagca agtagtgcat
    23761 aggttgcccg cacacggctc ccctcaatac cacgcaattg atctacagaa cgacggctcg
    23821 gcgcgggttc gccaaaacgt aattcaaaca ttttacgcac gaccttcagc cgcaaatctt
    23881 catccagtgc aagtttcgcc tgataaagca atttgtcgga acgggcacca ccaggctgcc
    23941 ccgaagcgta aacgcgtacg cccgcttccc ccccccacac cagtaacgta cccaccgttg
    24001 ccgcaagtcg cacggcggca tgggaaaccc gcgtccccgg ttccagcatg atgcaggcca
    24061 ccgatccaac aggaatatgg gtacgtacac ccgttttatc gataagcaca aacgcaccgt
    24121 cgatcacatc aatttgtccg tactggagaa atatcatcga aacacggtct ttcaacggga
    24181 tgggattcag cggcagccag ctcatcagcg tttccttttt accatcagca ttccgcagcc
    24241 cagcgcttta cttttaccta atccggaaaa taaagcctgt ttaaacagtg ctgcatcggt
    24301 gatacagagc gcaccgctaa aatcaacgct actgaaagtg attggggttt cctggtcttt
    24361 acggacaaaa cgatgttgct gatacgcttg cacgcatcca caatgcgcct gcaattcact
    24421 gtactcgtca ccagcccaca tagcgaaatc atcaggttcc ggtgcaatca accggaaacc
    24481 atgctgctgc ccttgttgtt ccagccacgc ctgcgcggcc tgctgttgaa gctcccacca
    24541 ccgttctttc tccacaccat tcgccttcgc ctgatgtttc gcgttcatca tcacgtcact
    24601 gcgcttaccg ttacgggtta tcaccgggtt agctcgtagt tgaaaatcaa gctcaagacc
    24661 atttgtcagt tgcggattaa atagtttggt ttcaataaga aacagggagt gctgcaataa
    24721 cggcggtatt gccgagagca taaaaaagcc gccatgcgcc tcttcgcgaa acagaaactg
    24781 acgcaattcc tgttccggaa agagctgcca taaccactgg tggctggcat aaggcctggc
    24841 tgaattccac tttgccaaca tctccggtcg caaattatta aaccggagtt gaatacgaga
    24901 aagatacatt atgttctctc ctgcaacggc ccattgaagc gggtgtagcc gccaaactgc
    24961 cagcgttggc ggctaactgg ctggttattg ctatgctgct tttgttgcca gaccagactc
    25021 tcctcatcag gatcatccca ataacaaata ccctcacgca gggtaaatcc acttaattcc
    25081 gctgcggaaa tctcctccac agcatgagtg aatacctctt ttaaggtgcc ggtcattaaa
    25141 cgcgccgcta acggtaacgc cagcgggcag gattttctcc ccagatagag cggaaaatgc
    25201 ggtgtcagca gcgcctctcg caattcgcta agcgaatatg gtgcatcagg cgtggcgctt
    25261 attgccacat gccagtagcc atcgcagcga tactctcgct gcgagataag cgttcccact
    25321 tcatccgacg cgagagtcag ttcatcccgg cgcgtgtaat aacgatactt tttgttttct
    25381 cgcggcgcgc taaccgtgtg ataatcccgc aaccagcgat cttgtgaagc caacgcgtgc
    25441 accgccagat gatagtgccg gttaaagtta ttcagccgcg cttcttcgtc gcgacgaatt
    25501 cctaacgctg cggcaagcag acccaatagc gcagagcgcg tgggaaccgt agctgagtgg
    25561 cgaatctcgc cagacgcttc ctccccccac gacgccagcg gcgcataaag ctgaaaaacc
    25621 agatattcct tcattattca tccttactgg ctaacaaagg ccagtaattc cgccagagat
    25681 cccgtacctt cctgaacgtt caactcacga taatcgtctg cacagtttcc atatacgcta
    25741 tcgaagctgg cgcgctgctg ttttaaacgg gttattgccg caggaatttg atcggtatcg
    25801 cgtaccggct ggaaaaatgc cgccgccaga gaacgcggtt gtttttgccc gacttcggcc
    25861 aacgcatagg tggcataggc acgagaagcg aagctgtttt gtttaccggt tggcgagacg
    25921 gttaacgctg tttcagtgag tgccgcgata gtacgcttcg ccagttcttc gttaccaccc
    25981 aggttttcca ccagcagatc gcggctgata cagacatagg tatagaaaag cgccgaggca
    26041 aaaccctgct cgcccatatg cccggaacct gcgtcttcct ctttattatt cagatcgtca
    26101 acggcggtga aaaaatcaga ctcaacggtc acggcactta cgcccaacgc atgggatacc
    26161 tgacaagcag cctcgacgtt gaactcaggc gatgacgcca gcatacggtc aaacagcgcc
    26221 atatctacgc tacgctgttc tttgcgcaga agcttcactt cttcatcgtt aggttcgcgt
    26281 ttgtcggcaa ttagcgtatc aaccagttgt ttaatcaaac taatttcatg gttactgacg
    26341 tgaacgatct gctcaatttc gagatttttt tccggtttcg catctttatc acttttaagc
    26401 ttgccaaatt gcttagcgat taactcagac gaactcttag caattttttc ttcaattccg
    26461 gcatctttca tcggacgata aacataatcc acgccaattc gacgagtacg cttacccata
    26521 aagccatcca ttgccgcttc aaaagtttcc gacacccgcc aggcacgctt cagactttgc
    26581 gacgatacgc gtaaacgctc aactcctccc ataaacgcgg tcttcggtct gccagactca
    26641 tcacgattca ggttagcggg cgcataagca gtcaataaat gcagttgaat aaaagttgtc
    26701 attatcaaat ccttctaaaa atgattattt gccacgcgac gtggaaagat attcgttcgc
    26761 ccaacggatg cgacttcgtt caaaggggtt acggaattcc ggctgatggt tttcgcgtcg
    26821 ttgccactct tccatccaca ggaaaatgcc atcggcaagt gaaagaacat tcaccccctc
    26881 cgtaccgcga atcttcactg cctgaatcaa caactggcaa aatgtttccg ggtcggacgc
    26941 tttttgcaaa cgttcaaaac gcagaccaga aacgcacgac gtggaacctt taagcttttc
    27001 ccctaactgc gcagcgaaac taatattctc cttatgactc ttaatatgca cagcgacgct
    27061 gacaaacaga gccagagcca tctcatcaag aggttgcagt cgcatatgtt taagcagagc
    27121 ctggcggaga gcgtcatgtc cttcacatat cattacgcca tatggcggcg ccattctttt
    27181 caactcagcc cgccaggcgc gaccgttgac tcgtttacca tccttgcgct cataacgctc
    27241 agacagcgta gcaaaccagt caagtagtgc cttctgcgca tcggggtgga gaattctgca
    27301 taacactgct gtattgctat tcagcatatt tggcttcctt ctgttattcg accagcgcca
    27361 acacatcctt gcgcgcttta tgtttacgat agctgctggc taaatcctgt cgggccgtca
    27421 gctggcgctg caggatatcg tccgggcagt cggggttggt cagggcatca cggtcaaaaa
    27481 cgtgaaatag atagtgtgct aattccgcct cccactgact tactgcgtga cgagtctgtg
    27541 tatcctgccg aagcggatcg acagccagcg cctcttgcaa cgtccgaaaa gcgggttcgg
    27601 tttcctgcca gaaggcgata tccaccatac taaaatccat tttggcttct ttcggacaat
    27661 cgaatttggc gctctttaac gcgttccgta acagcgacag cgactcacta gccagcacca
    27721 gcacaatgtt aagcgcagcg agaaattgct cttcgtgcga aacgctaatg agcggaattc
    27781 ggtgctgata ccagcagcgg accttggcct tattcatatc ccaggcaaag caccacaggc
    27841 tcattttgtt ccgctgacca gcggcacgaa cgacctttgc aggctgcatt ttgttgaact
    27901 tatcctcacg attgagcatc agccccaacc agtctttata acttaacccg cccggctgcc
    27961 ctttaaacgc cagccagggt gcggatggat ctttcaatgc ctgccgatat ggggagaagg
    28021 gatgtagcca actgtcgtac tgaacgccat aatttttact acgcatttgc agtagcagtg
    28081 attcgtgatg ctccccgcac aaatcgcaga tacctgccac agtgtgggtg aaatccagtt
    28141 ctatgcgccg cggcatcccc cagtaggctt gcaaggggtg cgcattatcc ggtgtgacca
    28201 cattccccgc tttttcgctg gttttcgtcg gcgcaagcca gggaaaaatg agtggatgct
    28261 gtgtaacatt cggcggctct tcctgcggca aaacgttaag ccaaagtttt ttccatagtg
    28321 gatatttatc ttcttcctgc ggtaccacca gcgtagtcag cggaccaccg ccgcgcatcc
    28381 ctacccggta acccgccccg ccggcaggtg aattggtttg aatcgcaaat agcgctatcg
    28441 ccgcgcagtg aggacatatt tgttctacgt tgccacgttt tacaaaatga tctttattga
    28501 gcttgagcgc attcccgccc ggcgcatcca ccagcagccc ggcaatagaa ccatattcac
    28561 tatcgagagg atcaaaactt tgcaggaagg aaggtttttg ctcgccgaac tgtagagcca
    28621 gagaaatcgt atttaacgcc ttctcccatt gttcgaattc gatactttca tgccagatat
    28681 ctgcccattc ttctttatct tccggcgcga cggtacattg taaaatacca atcagcattt
    28741 gccatgccgc cccctgaaag tcagcccgag gataggcaag atcctgaatg cggttatcca
    28801 gaagatcgcg taatgatatt ttctttttat cgccgtttga gaatatgacg ggaagccatt
    28861 tctctttggt taaatccata cctttactcc tgcagggcta tttattaagc caatttggaa
    28921 tattacctac ctataggtag attccgtcct gaggtatctc ttaaatactg tcatcggagt
    28981 tatactacat tttctcgaag acgaaaatat a
//
LOCUS       DAJVBX010000029        28815 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.029, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000029 DAJVBX010000000
VERSION     DAJVBX010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 28815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28815
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.029"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            23..2635
                     /gene="pepN"
                     /locus_tag="OPV72_001158"
     CDS             23..2635
                     /gene="pepN"
                     /locus_tag="OPV72_001158"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000193787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase N"
                     /protein_id="HCR9913520.1"
                     /translation="MTQQPQAKYRHDYRAPDYQITDIELTFDLDAEKTVVTAISQAVR
                     HGAPDAPLRLDGEDLTLVSIHVNDAPWTAYKEEEGALIISDLPERFTLRIVNEISPAA
                     NTALEGLYQSGDALCTQCEAEGFRHITWYLDRPDVLARFTTKIIADKSKYPFLLSNGN
                     RVAQGELENGRHWVQWQDPFPKPCYLFALVAGDFDVLRDTFTTRSGREVALELYVDRG
                     NLDRAPWAMTSLKNSMKWDETRFGLEYDLDIYMIVAVDFFNMGAMENKGLNIFNSKYV
                     LARTDTATDKDYLDIERVIGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDL
                     GSRAVNRISNVRTMRGLQFAEDASPMAHPIRPDKVIEMNNFYTLTVYEKGAEVIRMIH
                     TLLGEENFQKGMQLYFERHDGSAATCDDFVQAMEDASNVDLSHFRRWYSQSGTPIVTV
                     KDDYNPETEQYTLTISQRTPATADQAEKQPLHIPFAIELYDNEGNVIPLQKGGHPVNA
                     VLNVTQAEQTFTFDNVYFQPVPALLCEFSAPVKLEYKWSDQQLTFLMRHARNDFSRWD
                     AAQSLLATYIKLNVARHQQGQPLSLPVHVADAFRAVLLDEKIDPALAAEILTLPSANE
                     IAELFEVIDPIAIAQVREALTRTLAAELADEFLAIYNANHLDEYRVDHGDIGKRTLRN
                     ACLRFLTFGETELANTLVSKQYRDANNMTDALAALSAAVAAQLPCRDTLMQEYDDKWH
                     QDGLVMDKWFILQSTSPAENVLETVRSLLKHRSFSMSNPNRIRSLIGAFAGSNPAAFH
                     AQDGSGYQFLVEMLTDLNSRNPQVASRLIEPLIRLKRYDDKRQEKMRAALEQLKGLEN
                     LSGDLYEKITKALA"
     gene            2843..3853
                     /gene="pyrD"
                     /locus_tag="OPV72_001159"
     CDS             2843..3853
                     /gene="pyrD"
                     /locus_tag="OPV72_001159"
                     /EC_number="1.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinone-dependent dihydroorotate dehydrogenase"
                     /protein_id="HCR9913521.1"
                     /translation="MYYPFVRKALFQLDPERAHEFTFQQLRRITGTPLEALVRQKVPT
                     KPVTCMGLTFKNPLGLAAGLDKDGECIDALGAMGFGSLEIGTVTPRPQPGNDKPRLFR
                     LVDAEGLINRMGFNNLGVDNLVENVKKAHFDGILGINIGKNKDTPVENGKDDYLICME
                     KVYAYAGYIAINISSPNTPGLRTLQYGDALDDLLTAIKNKQNDLQVIHHKYVPVAVKI
                     APDLCEEELIQVADSLLRHNIDGVIATNTTLDRSLVQGMKNCQQTGGLSGRPLQLKST
                     EIIRRLSLELKGQLPIIGVGGIDSVIAAREKIAAGATLVQIYSGFIFKGPPLIKEIVT
                     HI"
     gene            4019..4561
                     /gene="zapC"
                     /locus_tag="OPV72_001160"
     CDS             4019..4561
                     /gene="zapC"
                     /locus_tag="OPV72_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapC"
                     /protein_id="HCR9913522.1"
                     /translation="MRIKPDDNWRWYYDEEHDRMMLDLANGMLFRSRFSRKMLTPDAF
                     CPTGFCVDDAALYFSFEEKCRDFELTKEQRAELVLNALVAIRYLKPQMPKSWHFVAHG
                     EMWTPGTGDAASVWLSDTAEQVNLLVVEPGENAALCLLAQPGVVIAGRTMQLGDAIKI
                     MNDRLKPQVHCHSFSLEQAV"
     gene            complement(4558..5667)
                     /locus_tag="OPV72_001161"
     CDS             complement(4558..5667)
                     /locus_tag="OPV72_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcbX family protein"
                     /protein_id="HCR9913523.1"
                     /translation="MATLSRLFIHPVKSMRGIGLTHALADISGLAFDRIFMVTESDGT
                     FITARQFPQMVRFTPSPLHDGLHLTAPDGSSALVRFTDFTPQDAPTEVWGNHFTARVA
                     PTAINQWLSGFFSRDVQLCWVGPQLTRRVKRHNAVPLGFADGYPYLLTNEASLRDLQQ
                     RCPAGVQMEQFRPNLVVSGVAAWEEDSWKVLRIGDVIFDVVKPCSRCIFTTVSPEKGQ
                     KHPSGEPLATLQAFRTAQDNGDVDFGQNLIARNSGVIRVGDEVEILATAPAKAYGATT
                     LDDSVTPEKHPDGSVTIDWQGQTFCGNNQQVLLEQLENQGIRIPYSCRAGICGCCRIR
                     LLEGEVSPLKKSAMGDDGTILSCSCVPKTALRLEN"
     gene            5766..7874
                     /gene="rlmKL"
                     /locus_tag="OPV72_001162"
     CDS             5766..7874
                     /gene="rlmKL"
                     /locus_tag="OPV72_001162"
                     /EC_number="2.1.1.173"
                     /EC_number="2.1.1.264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 23S rRNA
                     (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA
                     (guanine(2445)-N(2))-methyltransferase RlmL"
                     /protein_id="HCR9913524.1"
                     /translation="MNSLFASTARGLEELLKIELEKLGAVGCQVVQGGVHFQGDTRLI
                     YQSLMWSRLASRIILPMGECKVYSDLDLYFGVQAINWTEIFNPGATFAVHFSGLNDTI
                     RNSQYGAMKVKDAIVDAFTRKNLPRPNVDRESPDLRINVWLNKETASIALDLSGDGLH
                     LRGYRDRTGLAPIKETLAAAIVMRSGWQPGTPLLDPMCGSGTLLIEAAMWATDRAPGL
                     HRGHWGFSGWAQHDEAIWQEVKAEAQTRARKGLAEYSSHFYGSDSDARVIERARSNAR
                     RAGIGELITFEVKDVAQLSNPLPKGPYGTVISNPPYGERLDSDPALIALHSLLGRTMK
                     NQFGGWNLSLFSASPDLLGSLQLRADKQFKAKNGPLDCVQKNYHIAETTADSKPATVA
                     EDYANRLRKNLKKLEKWARQEGIECYRLYDADLPEYNVAVDRYGDWAVIQEYAPPKTV
                     DAQKARQRLFDIIAATLSVLGIPPNKLVLKTRERQKGKNQYQKMSEKGEFLEVSEYNA
                     RLWVNLTDYLDTGLFLDHRIARRMLGEMSKGKDFLNLFSYTGSASVHAGLGGARNTTT
                     VDMSRTYLEWAERNLRLNGLSGRAHRLIQADCLGWLREANEQFDLIFIDPPTFSNSKR
                     MEESFDVQRDHVALMKDLKRLLRKGGTIMFSNNKRGFRMDLEGLAELGLTAQEITQKT
                     LSPDFARNRQIHNCWLIRAA"
     gene            7887..9794
                     /locus_tag="OPV72_001163"
     CDS             7887..9794
                     /locus_tag="OPV72_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR9913525.1"
                     /translation="MSLISMHGAWLSFSDAPLLDNAELHIEDNERVCLVGRNGAGKST
                     LMKILNREQGLDDGRIIYEQDLIVARLQQDPPRNIAGSVYDFVAEGIEEQAEYLKRYH
                     EISRLVMTDPSEKNLNEMARVQEQLDHHNLWQLENRINEVLAQLGLDPNAALSSLSGG
                     WLRKAALGRALVSNPRVLLLDEPTNHLDIETIDWLEGFLKTFNGTIIFISHDRSFIRN
                     MATRIVDLDRGKLVTYPGNYDQYLLEKEEALRVEELQNAEFDRKLAQEEVWIRQGIKA
                     RRTRNEGRVRALKAMRRERSERREVMGTAKMQVEEATRSGKIVFEMENVDYQVEGKQL
                     VKDFSAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRIHVGTKLEVAYFDQHRA
                     ELDPEKTVMDNLAEGKQEVMVNGKPRHVLGYLQDFLFHPKRAMTPVRALSGGERNRLL
                     LARLFLKPSNLLILDEPTNDLDVETLELLEELIDGYQGTVLLVSHDRQFVDNTVTECW
                     IFEGGGKIGRYIGGYHDARAQQEQHLATKQPMTKKNEEVIAPKAEIVKRGSSKLSYKL
                     QRELEQLPGQLEDLEAKLEALQAQVADAAFFSQPHEQTQKVLADLSQAEQELEQAFER
                     WEYLEGLKNGA"
     gene            9809..11062
                     /gene="pqiA"
                     /locus_tag="OPV72_001164"
     CDS             9809..11062
                     /gene="pqiA"
                     /locus_tag="OPV72_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane integrity-associated transporter
                     subunit PqiA"
                     /protein_id="HCR9913526.1"
                     /translation="MCEHHHAAKHILCPQCDMLVALPRLSHGQKAACPRCGATLTTEW
                     DAPRQRPTAYALAALFMLLLSNLFPFVNMNVAGVTSEVTLLEIPGVMFSEDYASLGTF
                     FLLFVQLVPAFCLVTILLLVNRASLPLSVKKTLARIFFLLKSWGMAEIFLAGVLVSFV
                     KLMAYGDIGIGSSFIPWCLFCLVQLRAFQCVDRRWLWDDIAPQPALAQPLTPGITGIR
                     QSLRSCACCTAILPAESLVCPRCHTKGYVRRKNSLQWTLALLFTSIMLYLPANILPIM
                     ITDLLGSKMPSTILAGVILLWSEGSYPVAAVIFLASIMVPTLKMIAIAWLCWDAKGHG
                     KRDSERMHFIYEVVEFVGRWSMIDVFVIAVLSALVRMGGLMNIYPAMGALMFALVVIM
                     TMFSAMTFDPRLSWDREYEPGHEES"
     gene            11067..12707
                     /gene="pqiB"
                     /locus_tag="OPV72_001165"
     CDS             11067..12707
                     /gene="pqiB"
                     /locus_tag="OPV72_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="intermembrane transport protein PqiB"
                     /protein_id="HCR9913527.1"
                     /translation="MEPKKGEAKVQKVKNWSPVWIFPIVTALIGAWILFYHYSHQGPE
                     VTLITTNAEGIEGGKTTIKSRSVDVGVVESATLTDDLTHVQIKARLHSGMEKLLHKDS
                     VFWVVKPQVGREGISGLGTLLSGAYIELQPGSKGSQPESYQLLDSPPLAPPDAKGIRV
                     ILDSKKAGQLSPGDPVLFRGYRVGSVETSSFDPQKRTMSYQLFIKAPNDRLVTSNVRF
                     WKDSGIAVDLTSAGMRVEMGSLTTLFGGGVSFDVPEGLEQGQPVAEKTAFNLYDDQKS
                     IQDSLYTDHIDYLMFFKDSVRGLQPGAPLEFRGIRLGTVSKVPFFASNMRQVFNDDYR
                     IPVLVRIEPERLKAQLGENADVGAHLTELLKRGLRASLKTGNLVTGALYVDLDFYPKE
                     PPITGLREFDGYEIIPTVSSGLAQIQQRLVETLDKINNLPLNPMIEQATNTLSESQRT
                     MRRLQTTLDNMNKITSSQSMQQLPADMQTTLRELNRSMQGFQPGSAAYNKMVADMQRL
                     DQVLRELQPVLKTLNEKSNALVFEAKDKKDPEPKRAKQ"
     gene            12704..13267
                     /gene="pqiC"
                     /locus_tag="OPV72_001166"
     CDS             12704..13267
                     /gene="pqiC"
                     /locus_tag="OPV72_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane integrity-associated transporter
                     subunit PqiC"
                     /protein_id="HCR9913528.1"
                     /translation="MKKWLVVIMAFWLASCSSGGENKSYYQLPIAQSGVQSTASQGNR
                     LLWVEQVSVPDYLAGNGVVYQTSDVQYVIANNNLWASPLDQQLRNTLVANLSARLPGW
                     VVASQPLGTTQDTLNVTVTGFHGRYDGKVIVSGEWLLNHNGQLIKRPFHIEASQQKDG
                     YDEMVKVLASAWSQEAAAIADEIKRLP"
     gene            13521..13688
                     /gene="rmf"
                     /locus_tag="OPV72_001167"
     CDS             13521..13688
                     /gene="rmf"
                     /locus_tag="OPV72_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome modulation factor"
                     /protein_id="HCR9913529.1"
                     /translation="MRRQKRDRLERAHQRGYQAGIAGRSKEMCPYQTLNQRSYWLGGW
                     RQAMEDRAVMA"
     gene            complement(13788..14306)
                     /gene="fabA"
                     /locus_tag="OPV72_001168"
     CDS             complement(13788..14306)
                     /gene="fabA"
                     /locus_tag="OPV72_001168"
                     /EC_number="4.2.1.59"
                     /EC_number="5.3.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014915875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 3-hydroxydecanoyl-ACP
                     dehydratase/trans-2-decenoyl-ACP isomerase"
                     /protein_id="HCR9913530.1"
                     /translation="MVDKRESYTKEDLLASGRGELFGAKGPQLPAPNMLMMDRVVKMT
                     ETGGNFDKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEG
                     KGRALGVGEVKFTGQVLPTARKVTYRIHFKRIVNRRLIMGLADGEVLVDGRLIYTAHD
                     LKVGLFQDTSAF"
     gene            complement(14375..16135)
                     /locus_tag="OPV72_001169"
     CDS             complement(14375..16135)
                     /locus_tag="OPV72_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lon protease family protein"
                     /protein_id="HCR9913531.1"
                     /translation="MTITKLAWRDLVPDSESYQEIFAQPHATDENDTLLSDTQPRLQF
                     ALEQLIQPWASSSFMLTKAPEEQEYLTLLSDAVRALQTDAGQLTGGHYDVSGHTVHYR
                     AAQNAQDNFATVTQVVSADWVEAEQLFGCLRQYNGDITLQPGLVHQANGGVLIISLRT
                     LLAQPLLWMRLKAIVSRERFDWVAFDESRPLPVSVPSMPLKLKVILVGERESLADFQE
                     MEPELAEQAIYSEFEDNLQIADAEAMTLWCQWVTRIALRDNLPPPAPDAWPVLIREAV
                     RYTGEQDTLPLCPLWIARQFKEASPLCEGDTCGAEALSLMLARREWREGFLAERMQGE
                     ILQEQILIETEGERVGQINALSVIEFPGHPRAFGEPSRISCVVHIGDGEFNDIERKAE
                     LGGNIHAKGMMIMQAFLMSELQLEQQIPFSASLTFEQSYSEVDGDSASMAELCALISA
                     LANVPVNQNIAITGSVDQFGRAQPVGGLNEKIEGFFAICEQRELNGKQGVIIPAANVR
                     HLSLKSELLQAVKEEKFTIWAVDDVTDALPLLLNLVWDGEGQTTLMQTIQERIAQATQ
                     QEGRHRFPWPLRWLNAFIPN"
     gene            16321..16773
                     /gene="matP"
                     /locus_tag="OPV72_001170"
     CDS             16321..16773
                     /gene="matP"
                     /locus_tag="OPV72_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrodomain Ter protein MatP"
                     /protein_id="HCR9913532.1"
                     /translation="MKYQQLENLESGWKWKYLVKKHREGELITRYVEASAAQEAVNLL
                     LALENEPVRVNVWIDRHMNPALLNRMRQTIRARRKRHFNAEHQHTRKKSIDLEFMVWQ
                     RLAGLAQRRGKTLSETIVQLIEDAEHKEKYATQMTTLKQDLQALLGKK"
     gene            complement(16845..17897)
                     /gene="ompA"
                     /locus_tag="OPV72_001171"
     CDS             complement(16845..17897)
                     /gene="ompA"
                     /locus_tag="OPV72_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpA"
                     /protein_id="HCR9913533.1"
                     /translation="MKKTAIAIAVALAGFATVAQAAPKDNTWYAGAKLGWSQYHDTGF
                     IHNDGPTHENQLGAGAFGGYQVNPYVGFEMGYDWLGRMPYKGDNTNGAYKAQGVQLTA
                     KLGYPITDDLDVYTRLGGMVWRADTKSNVPGGASTKDHDTGVSPVFAGGIEYAITPEI
                     ATRLEYQWTNNIGDANTIGTRPDNGLLSVGVSYRFGQQEAAPVVAPAPAPAPEVQTKH
                     FTLKSDVLFNFNKSTLKPEGQQALDQLYSQLSNLDPKDGSVVVLGFTDRIGSDAYNQG
                     LSEKRAQSVVDYLISKGIPSDKISARGMGESNPVTGNTCDNVKPRAALIDCLAPDRRV
                     EIEVKGVKDVVTQPQA"
     gene            complement(18252..18761)
                     /gene="sulA"
                     /locus_tag="OPV72_001172"
     CDS             complement(18252..18761)
                     /gene="sulA"
                     /locus_tag="OPV72_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division inhibitor SulA"
                     /protein_id="HCR9913534.1"
                     /translation="MYTSGYANRSSSFPTTTHNAARTATENAAAGLVSEVVYHEDQPM
                     MAQLLLLPLLRQLGQQSRWQLWLTPQQKLSREWVQSSGLPLTKVMQISQLAPRHTLES
                     MIRALRTGNYSVVIGWMTEELTEEEHASLVEAAKVGNAVGFIMRPVRAHALPRRQHSG
                     LKIHSNLYH"
     gene            18978..19583
                     /locus_tag="OPV72_001173"
     CDS             18978..19583
                     /locus_tag="OPV72_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family DNA transformation protein"
                     /protein_id="HCR9913535.1"
                     /translation="MRALSYDRIYESQEYLASLGTIQYRSLFGSYSLTVEDTVFAMVA
                     NGELYLRACEESVPYCVKHPPAWLMFMKCGRPVMLNYYRVDESLWRDQQQLVRLSKYS
                     LDAAMKEKHSRILQHRLKDLPNMTFHLETLLNESGIKDENMLRILGAKMCWLRLRQSN
                     PLLTVKVLYALEGAIVGVHEAALPASRRQELADWAHSLTAG"
     gene            complement(19570..21723)
                     /gene="yccS"
                     /locus_tag="OPV72_001174"
     CDS             complement(19570..21723)
                     /gene="yccS"
                     /locus_tag="OPV72_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01666 family membrane protein"
                     /protein_id="HCR9913536.1"
                     /translation="MLSPLIRRYTWNSTWLYYIRIFIALCGTTALPWWLGDVKLTIPL
                     TLGMVAAALTDLDDRLAGRLRNLIITLICFFIASASVELLFPWPWLFALGLTLSTSGF
                     ILLGGLGQRYATIAFGALLIAIYTMLGASLYDHWYQQPLLLLAGAVWYNLLTLTGHLL
                     FPIRPLQDNLARSYEQLAHYLELKSRLFDPDIEDESQAPLYDLALANGQLMATLNQTK
                     VSLLTRLRGDRGQRGTRRTLHYYFVAQDIHERASSSHIQYQTLRDYFRHSDVMFRFQR
                     LMSMQAQACTQLARCILLRTPYQHDPRFERVFTHIDAALERMRASGASLELLNTLGFL
                     LTNLRAIDAQLATIESEQAQAMPRNESENQLADDSLHGFSDIWLRLSRNFTPESALFR
                     HAVRMSLVLCIGYALIQITGMRHGYWILLTSLFVCQPNYNATRHRLALRIIGTLVGVA
                     IGLPILWFVPSLEGQLVLLVITGVLFFAFRNVQYAHATMFITLLVLLCFNLLGEGFEV
                     ALPRVIDTLIGCAIAWAAVSFIWPDWRFRNLPRVLQRATDANCRYLDAILEQYHQGRD
                     NRLAYRIARRDAHNRDAELASVVSNMSSEPDVTAETREAAFRLLCLNHTFTSYISALG
                     AHREKLSNPDVLGLLDDAVCYVDDALHHQPEDEQRVHQALEGLKQRVQSLETRPDSKE
                     PLVVQQIGLLIALLPEIGRLQRQISPPTSTLITQP"
     gene            complement(21742..22188)
                     /locus_tag="OPV72_001175"
     CDS             complement(21742..22188)
                     /locus_tag="OPV72_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HCR9913537.1"
                     /translation="MRTVLNILNFVLGGFATTLAWLLATLVSIVLIFTLPLTRSCWEI
                     TKLSLFPYGNEAIHVDELNPAAKSVLMNTGGTLLNIFWLLFFGWWLCLMHIASGIAQC
                     VTIIGIPVGIANFKIAAIALWPVGRRVVSVETARAAREANARRRFE"
     gene            22312..24366
                     /gene="helD"
                     /locus_tag="OPV72_001176"
     CDS             22312..24366
                     /gene="helD"
                     /locus_tag="OPV72_001176"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase IV"
                     /protein_id="HCR9913538.1"
                     /translation="MELKATSLGKRLAQHPYDRAVILNAGVKVSGDRHEYLILFNQLL
                     AIHCKRGLVWGELEFVLPEDKVVRLHGTEWSETQQFHRYLDAHWRRWSQEMSDVAAQA
                     LQEQWARISERTGGNQWLTREHVRGLEHEIRQTFAALPLPVSRLEEFAHCREIWRKCL
                     AWLQDSEGSRQQHNQAYADAMLEAHADFFTQIESSPLNPSQARAVVNGESSLLVLAGA
                     GSGKTSVLVARAGWLLARGQADAGQILLLAFGRKAAEEMDERIRERLHTEEITARTFH
                     SLALYIIQQGSKKAPVVSKLESDATARHQLFLHTWRQQCSEKKAQAKGWRQWLEEEMQ
                     WVVPEGNFWDDETLQRRLAPRLDRWVSLMRMHGGAQAEMIAGAPEECRELFGKRIKLM
                     APLLKAWKSALKAENAVDFSGLIHQAMVILEKGRFISPWKHILVDEFQDISPQRAALL
                     EALRKQNSQTTLFAVGDDWQAIYRFSGAQLSLTTAFHQTFGEGEHCHLDTTYRFNSRI
                     GDIANRFVQQNPHQLKKPLNSLTPGDKKAVTLLDESQLDALLDKLSGYAKEDERILVL
                     ARYHHLKPASLQKAATRWPKLQIDFMTIHASKGQQADYVILVGLQEGNDGFPAPARES
                     IMESALFPQVEDFPDAEERRLLYVALTRARARVWLLFNKDNPSRFVEALKQLDVPVAR
                     KP"
     gene            complement(24402..24860)
                     /gene="mgsA"
                     /locus_tag="OPV72_001177"
     CDS             complement(24402..24860)
                     /gene="mgsA"
                     /locus_tag="OPV72_001177"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HCR9913539.1"
                     /translation="MELTTRTLPTRKHIALVAHDHCKQMLMNWVERHQPLLEKHVLYA
                     TGTTGNLIQRATGMDVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDV
                     KALLRLATVWNIPVATNVSTADFIIQSPHFNDAVDILIPDYARYLAERLK"
     gene            complement(24955..25617)
                     /locus_tag="OPV72_001178"
     CDS             complement(24955..25617)
                     /locus_tag="OPV72_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2057 family protein"
                     /protein_id="HCR9913540.1"
                     /translation="MKTGALATFLALCLPVTVFATTLRLSNEVDLLVLDGKKVSSSLL
                     RGAESIELENGPHQLVFRVEKTIRLPGNEERLYISPPLVISFDTQLISQVNFQLPRLE
                     NEREASHFNAAPRLALLDGDAMPIPVKLDILAITSTAKVVDYEIETERYNKSAKRASL
                     PQFATMMADDSTLLSDVSELDTVPPQSQTLTEQRLKYWFRLADPQTRHHFLQWAEKQP
                     PS"
     gene            25791..26204
                     /locus_tag="OPV72_001179"
     CDS             25791..26204
                     /locus_tag="OPV72_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HCR9913541.1"
                     /translation="MKETDIADVLTSTRTIALVGASDKPDRPSYRVMKYLLEQGYHVI
                     PVAPKVAGKTLLGQQGYATLADIPEKVDMVDVFRNSEAAWGVAQEAIAIGAKTLWLQL
                     GVINEQAAVLARDAGMTVVMDRCPAIEIPRLGLAK"
     gene            complement(26249..26566)
                     /gene="hspQ"
                     /locus_tag="OPV72_001180"
     CDS             complement(26249..26566)
                     /gene="hspQ"
                     /locus_tag="OPV72_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock protein HspQ"
                     /protein_id="HCR9913542.1"
                     /translation="MIASKFGIGQQVRHSLLGYLGVVVDIDPEYSLDEPSPDELAVND
                     ELRAAPWYHVVMEDDDGQPVHTYLAEAQLRSEMRDEHPEQPSMDELARTIRKQLQAPR
                     LRN"
     gene            complement(26624..27835)
                     /gene="rlmI"
                     /locus_tag="OPV72_001181"
     CDS             complement(26624..27835)
                     /gene="rlmI"
                     /locus_tag="OPV72_001181"
                     /EC_number="2.1.1.191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (cytosine(1962)-C(5))-methyltransferase
                     RlmI"
                     /protein_id="HCR9913543.1"
                     /translation="MTESTFPQYPRLVLSKGREKSLLRRHPWVFSGAVSRLEGKANLG
                     ETIDIVDHQGKWLARGAWSPASQIRARVWTFDKTESIDIAFFTRRLRQAQQWRDWLAK
                     KDGLDSYRLIAGESDGLPGVTIDRFGHFLVLQLLSAGAEYQRAALISALQTCYPDCAI
                     YDRSDVAVRKKEGMALTQGPVTGELPPALLPIEEHGMKLLVDIQGGHKTGYYLDQRDS
                     RLVTRRYVENQRVLNCFSYTGGFAVSALMGGCRQVVSVDTSQDALDIARQNVELNQLD
                     LSKAEFVRDDVFKLLRAYREHGEKFDVIIMDPPKFVENKSQLMGACRGYKDINMLAIQ
                     LLNPGGILLTFSCSGLMTSDLFQKIIADAAIDAGRDVQFIEQFRQAADHPVIATYPEG
                     LYLKGFACRVM"
     gene            28050..28597
                     /locus_tag="OPV72_001182"
                     /pseudo
     CDS             28050..28597
                     /locus_tag="OPV72_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460055.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YbhB/YbcL family Raf kinase inhibitor-like
                     protein"
     gene            28623..>28815
                     /locus_tag="OPV72_001183"
     CDS             28623..>28815
                     /locus_tag="OPV72_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCR9913544.1"
                     /translation="MHIRHQDLTTAEVRSSHLHRLHRVTLFSAAICHITQGSKVIIQD
                     DSRLVAGPGELIIIPANTPL"
BASE COUNT         7064 a         7127 c         7940 g         6684 t
ORIGIN      
        1 acaaagatgc gaaaggtttt ttatgacaca acagccacaa gccaaatacc gccatgacta
       61 tcgcgcgccg gattaccaga ttactgatat tgaattgacc tttgacctcg atgccgaaaa
      121 aaccgtggtc accgcaataa gccaggctgt tcgtcatggc gcgcctgatg cgcctcttcg
      181 ccttgatggg gaagatttaa cgctggtatc tatccacgtc aacgatgcgc cgtggacagc
      241 atataaggaa gaagagggcg cgcttatcat cagcgacctg ccagagcgtt ttacgttacg
      301 cattgtcaac gagataagtc cggcggcgaa tacggcgctg gaaggattgt accagtccgg
      361 cgatgcgctc tgtacccagt gtgaagcgga gggcttccgc catattacct ggtatcttga
      421 ccgcccggac gtactggcgc gatttaccac caaaattatt gccgataaaa gcaaatatcc
      481 gttcctgctt tccaatggca accgtgttgc gcagggtgaa ctggagaatg gccgtcactg
      541 ggttcagtgg caagatccgt tcccgaaacc gtgttatctg tttgcgctgg tggccggtga
      601 ttttgacgtg ctgcgcgata cctttaccac ccgctccggg cgtgaagtcg cattagaact
      661 gtacgttgac cgtggcaatc tggatcgcgc gccgtgggca atgacctcgc tgaaaaattc
      721 catgaaatgg gatgaaacgc gttttgggct cgaatatgac ctcgacatct atatgattgt
      781 cgcggtggat ttctttaata tgggcgcgat ggagaataaa ggtctcaata tctttaactc
      841 caaatacgtg ctggcgcgaa ccgataccgc gacggataaa gattatctcg atattgagcg
      901 cgtgataggc catgagtatt tccacaactg gaccggcaac cgcgtcacct gccgcgactg
      961 gttccagttg agcctgaaag aggggctcac cgtgttccgc gatcaggagt ttagctctga
     1021 tttggggtca cgcgcggtga accgcatcag taacgtgcgt accatgcgcg gtttacaatt
     1081 cgcggaagac gccagcccga tggcgcatcc tatccgcccg gataaagtaa tcgaaatgaa
     1141 taacttctac accctcaccg tttatgaaaa gggtgcggaa gtcattcgca tgatccacac
     1201 gttgctgggt gaggaaaatt tccagaaggg gatgcagctt tattttgagc gccatgacgg
     1261 cagcgccgcg acgtgtgatg acttcgtaca ggcgatggaa gatgcttcta atgtcgattt
     1321 gtcccatttc cgccgctggt acagtcagtc cggcacgccg attgtaacgg taaaagatga
     1381 ttataatccg gaaaccgagc agtacacgtt gaccatcagc cagcgcactc cggcgacggc
     1441 ggatcaggcg gagaagcagc cgctgcatat tccattcgcc atcgaactgt acgataacga
     1501 aggcaacgtc attccgttgc aaaaaggcgg tcacccggtc aatgccgtgc tgaacgtcac
     1561 gcaggcggag cagacattta ccttcgataa tgtctacttc cagcctgttc cggccttgct
     1621 gtgcgagttt tcagcgccgg tgaagctgga atataaatgg agcgatcagc agttgacgtt
     1681 cctgatgcgc catgcgcgca atgatttctc ccgttgggat gcggcgcaaa gcctgctggc
     1741 cacatacatt aaactgaatg tggcgcgtca tcagcagggg caaccgctat cgcttccggt
     1801 gcatgtcgct gatgcgttcc gtgcagtact gttggatgag aaaatcgatc cggcgttggc
     1861 cgcagaaatt ttaacgctgc cttcggccaa tgaaattgcg gagctgtttg aggtcattga
     1921 cccgatcgcc attgcgcaag ttcgtgaagc gctaacgcgt acgctggcgg cagaactggc
     1981 ggatgagttc ctggctatct ataacgccaa tcatctggat gagtatcgtg ttgatcacgg
     2041 cgatatcggt aagcgcacgc tgcgcaatgc ttgcctgcgc ttcctgacgt tcggcgagac
     2101 ggagctggct aatacgctgg tcagcaaaca gtatcgcgac gccaataata tgaccgatgc
     2161 gctggcggcc ctgtctgctg cagtggcggc gcagttgccg tgccgcgata cgctgatgca
     2221 ggagtatgac gataagtggc atcaggacgg cctggtaatg gataaatggt ttatcctgca
     2281 atccacaagc ccggcggaaa atgtactgga aaccgtacgc agcctgctca aacaccgttc
     2341 tttcagtatg agcaacccga accgcatccg ttcattaatt ggcgcgtttg ctggcagcaa
     2401 cccggcggcg ttccatgcgc aagacggtag cggataccag ttcctggtcg agatgctgac
     2461 cgatctgaat agccgtaacc cgcaggtagc atctcgcctc attgaaccgc tgattcgtct
     2521 gaaacgttat gatgataagc gtcaggagaa aatgcgcgcg gcgctggagc agttaaaagg
     2581 actggagaat ctttccggcg atctgtacga gaagataact aaagcgttag cctgacagta
     2641 tccgttataa agaggtaaaa catgcccggt aagcgttagc gctgccgggt atttttttgc
     2701 cggatgatga cgcttcctgg cgaaacgtga agtgagaatg aaggaaaacg attgctattt
     2761 attgccatag gtcaattccc ttttgctttg ttatcgccca taatacgccc ccggtttgca
     2821 caccgggaat ccaggagagt tcatgtacta tcccttcgtt cgtaaagccc ttttccagct
     2881 cgatccagag cgcgctcatg aatttacatt tcaacaatta cgccgcatta caggtacgcc
     2941 gctggaagcg ctggtgcgcc agaaagtacc gacaaagccg gttacctgca tgggacttac
     3001 ctttaaaaat ccactggggc tggctgccgg tctggataaa gacggggagt gcatcgacgc
     3061 attaggcgcg atggggtttg gctccctgga aatcggcacc gtgacgccgc gcccacagcc
     3121 gggtaacgat aagccacgtc tttttcgtct ggtggatgct gaaggtctaa tcaatcggat
     3181 gggctttaat aatctgggcg tcgataacct ggtcgagaat gttaaaaaag cccattttga
     3241 tggtattctg ggaattaaca tcggtaaaaa taaagatacg cctgtcgaaa atggcaaaga
     3301 tgactacctg atttgtatgg aaaaagtcta tgcttatgcg ggttatatcg ccattaatat
     3361 ttcttcgccg aatacgccag ggttacgtac gctccagtat ggcgatgcgc tggacgatct
     3421 gttaactgcc attaaaaata agcaaaacga tcttcaggtg atccaccata aatatgtgcc
     3481 ggtggcagta aagatcgcgc cggatctttg tgaagaagaa ttgatccagg ttgccgatag
     3541 cctgcttcgt cataatattg atggggtgat tgcgacaaat accaccctcg atcgttctct
     3601 ggtacaagga atgaaaaatt gccagcaaac ggggggatta agtggccggc cattacaatt
     3661 aaaaagcaca gaaattattc gccgtttatc cctggagtta aaaggacaat tgcctattat
     3721 cggcgtcggc ggcattgact cagttatcgc cgcgcgcgag aagatagcgg caggagctac
     3781 gctggtacaa atttattccg gctttatttt taaaggcccg ccattgatta aagaaatcgt
     3841 aacgcacatc taaactttac cctttatcag acaaccaggg ctttatttcc ggcactggtt
     3901 gttttatatt tctccactgt tgcttattta gacattttag gcttttatta ttggggtaat
     3961 aaacgaagcg gcaaaaggac aatgctgtta cgagttgctt aaaagcggga gagaggtgat
     4021 gcgaattaaa cctgacgata actggcgctg gtattatgat gaagagcacg atcgtatgat
     4081 gctcgatctc gccaatggta tgctttttcg ctcgcgcttc tctcgtaaaa tgcttacgcc
     4141 ggacgcgttt tgcccgaccg gtttttgtgt ggatgatgcc gcgctctatt tttcctttga
     4201 agaaaaatgc cgggatttcg aattaaccaa agagcaacgc gcggagctgg tattgaatgc
     4261 gctggtggcg attcgctatc tcaaaccgca gatgccgaaa agctggcatt ttgtggcgca
     4321 tggcgaaatg tggaccccgg gcacgggtga tgccgcaagc gtctggttaa gcgatacggc
     4381 ggaacaggtt aatttgctgg tcgttgagcc gggagaaaat gccgcgttgt gtctgctggc
     4441 acagccaggc gtggtgatag caggccgaac catgcagctt ggcgatgcga ttaaaattat
     4501 gaacgacagg ctgaaaccgc aggttcactg tcacagtttc agccttgaac aagcggttta
     4561 attttccagt cgtaacgcgg tcttaggcac gcagctacag ctcagaatcg taccatcgtc
     4621 acccatagcc gattttttca gcggacttac ttcgccttcc agcaaacgta tccggcagca
     4681 accacagata ccagcccggc aagaatacgg aatacgaatt ccctgattct ccaactgttc
     4741 cagtagcacc tgttgattat tcccgcagaa ggtttgcccc tgccagtcga tggttacact
     4801 cccgtccggg tgtttctctg gcgtaacgct gtcgtcgagc gttgtggcgc cataagcttt
     4861 tgccggcgct gtcgccagta tctccacctc atcgccgacg cgaatgacgc cgctattgcg
     4921 ggcaatcaga ttctgaccga aatccacatc gccattgtcc tgggcggtac gaaaagcttg
     4981 cagtgtcgcc agcggttcgc cggaaggatg tttttgcccc ttttcagggc tgacggtcgt
     5041 aaaaatacag cgactacagg gcttcacgac gtcaaaaatc acatcgccaa tgcgaagcac
     5101 tttccagcta tcttcctccc aggccgctac gccggaaacc actaagtttg ggcgaaattg
     5161 ttccatttgt acgcctgccg gacaacgctg ttgcagatcg cgcagtgagg cttcgttggt
     5221 caataaatac gggtagccat cggcaaatcc cagcggcacc gcgttatgcc gtttaacccg
     5281 gcgcgtcaac tgcggcccaa cccagcacaa ctggacatcg cgggagaaaa agccgctcaa
     5341 ccattgatta atcgccgtcg gggcgacgcg agcggtaaaa tggtttcccc agacctcggt
     5401 cggcgcatcc tgcggggtga aatccgtaaa gcgaaccagc gcgctgctgc cgtctggcgc
     5461 ggtcaaatgg aggccgtcgt gtaagggaga gggggtaaaa cgtaccattt gtggaaactg
     5521 gcgggcggta ataaatgtgc cgtcagactc ggttaccatg aagatgcgat caaaagccag
     5581 gccgctgata tctgccagcg catgagtcag gccaatgccg cgcatggatt tgaccggatg
     5641 aataaagagc cgtgataacg tcgccaccgt acagtccctc aaatgaaaat aagccttcaa
     5701 ctttatgaca tgggcgtgag attagctata atgcgcaaca attttcttag cgtaaaagtg
     5761 acaatatgaa ttctctgttt gccagtacgg cccgcgggct ggaagagctg ttaaaaattg
     5821 aactggaaaa actgggcgcc gtagggtgtc aggttgttca gggtggggtc cattttcagg
     5881 gcgacacgcg gcttatttac cagagcctga tgtggagccg cctggcctcg cgtattatcc
     5941 tgccgatggg tgagtgcaag gtctacagcg atctcgatct ttacttcggc gttcaggcga
     6001 taaactggac agagattttt aatcctggcg cgacgtttgc ggtgcatttc agcggcctga
     6061 acgacaccat ccgtaatagt cagtatggcg cgatgaaagt taaagacgcg attgtcgatg
     6121 cgtttacgcg gaaaaatctt ccgcgtccaa atgtggaccg cgaatcgccg gacctccgta
     6181 ttaacgtctg gctgaataaa gaaacggcca gcattgcgct ggatctcagt ggtgatggcc
     6241 tgcacctgcg cggttatcgc gatcgcaccg ggctggcgcc aattaaagag acgctggcgg
     6301 cagcgattgt tatgcgttcc ggctggcaac caggtacgcc gctgctcgac cctatgtgtg
     6361 gttcggggac actgttgatt gaggccgcga tgtgggcgac cgatcgcgcg ccgggcctgc
     6421 atcgtggtca ctggggattt agcggctggg cgcagcatga cgaggctatc tggcaggaag
     6481 tgaaagccga agcgcagacc cgggcgcgta aggggctggc ggagtattcc tctcatttct
     6541 acggttccga cagcgatgcg cgcgtcattg agcgggcgcg cagcaacgcc cgtcgcgccg
     6601 gtatcgggga gcttatcact tttgaagtga aagatgtggc gcaactgagt aatccattgc
     6661 cgaaaggccc gtatggtacg gtgatcagta acccgcctta cggcgaacgt ctggacagcg
     6721 atccggcgct gattgcgttg cacagcctgt tgggccgtac catgaaaaat cagtttggcg
     6781 gctggaacct gtcgctgttc agcgcttcgc ccgatttgct gggcagcctg caattacgcg
     6841 ccgacaaaca gtttaaagcc aagaatggcc cgctggactg tgtgcagaaa aactatcata
     6901 ttgcggaaac cacggcggac agtaaaccgg cgacggtggc ggaagattac gctaatcgcc
     6961 tgcgtaaaaa tcttaaaaag ctggagaaat gggcgcgcca ggaagggatt gaatgctatc
     7021 gcttgtatga tgccgacctg ccggaatata acgtggcggt agaccgttac ggcgactggg
     7081 cggtgattca ggaatatgcg ccgccgaaaa cggtggatgc gcaaaaagcg cggcaacgtc
     7141 tgttcgatat tattgcggca accttgtcag tgctcggtat tccgccgaat aaactggtgt
     7201 taaaaacccg cgaacggcaa aaaggaaaaa accagtatca gaaaatgagc gagaagggcg
     7261 agttccttga ggtcagcgaa tataatgcgc gcttatgggt aaatctgacg gattatctcg
     7321 acactggtct gttcctcgat caccgtattg cccgcagaat gctgggagaa atgagcaaag
     7381 gcaaagattt cctgaatctc ttttcttata ccggcagcgc cagcgtacat gcgggtctgg
     7441 gcggcgcgcg caacaccaca acggtggata tgtcccgcac ctatctggag tgggccgaac
     7501 gtaatttgcg tctgaacgga ctgagcggcc gcgcgcatcg cctgattcag gccgactgcc
     7561 tgggctggct gcgcgaggcg aatgaacagt tcgatttgat ctttatcgat ccgccgacgt
     7621 tctctaactc aaaacgtatg gaagagtcgt ttgatgttca gcgcgatcat gtcgcgttaa
     7681 tgaaagattt aaaacgcctg ctgcgtaaag gcggcaccat catgttctca aataataagc
     7741 gcggattccg tatggatctg gaagggctgg ctgagctggg gcttaccgca caagaaatta
     7801 cgcaaaaaac gctttccccg gattttgccc gtaaccgtca gattcataat tgctggctga
     7861 tccgcgccgc ctgaaaggaa aagtaaatgt cattaatcag tatgcatggc gcatggctgt
     7921 cgttcagcga cgcgccgctt ctcgataacg cagagttgca tatcgaagat aacgaacgcg
     7981 tctgtctggt ggggcgtaac ggcgccggga aatccacctt gatgaagatc ctcaaccgcg
     8041 aacagggtct ggacgatggg cgtattattt atgaacagga tctgatcgtc gcgcgtctgc
     8101 aacaggaccc gccccgtaat attgcgggta gcgtctatga ctttgtcgcc gaaggtatcg
     8161 aagaacaagc ggaatatctc aagcgctatc atgagatttc ccgtctggtg atgaccgatc
     8221 ccagcgagaa aaacctcaat gaaatggcgc gcgtacagga acagctcgat catcataatc
     8281 tgtggcagct ggaaaaccgt attaatgaag tgctggcgca gcttggactc gatcctaacg
     8341 ccgcgctgtc gtcgctctcc ggcggctggc tgcgtaaagc cgcgctgggt cgggcgctgg
     8401 tcagcaatcc gcgcgtattg ttactggatg aaccgactaa ccatctggat atcgaaacta
     8461 tcgactggct ggaagggttt ctgaaaacct ttaacggaac gattattttt atctctcacg
     8521 atcgttcgtt tattcgcaat atggcgaccc gcattgtcga tctcgatcgt ggcaaactgg
     8581 tcacctatcc gggaaattac gatcaatacc tgctggagaa agaagaagcg ctgcgcgtag
     8641 aagagttaca aaacgcggaa tttgatcgca aactggcaca ggaagaagtc tggattcgcc
     8701 aggggatcaa ggcgcgccgc acccgtaatg aagggcgcgt gcgggcgtta aaagcgatgc
     8761 gtcgtgaacg cagcgagcgc cgggaagtga tgggcacggc gaagatgcag gtcgaagagg
     8821 cgacgcgctc cggtaaaatc gtttttgaga tggaaaacgt cgattaccag gtagaaggaa
     8881 aacagctggt aaaagatttc tccgctcagg tacagcgcgg cgacaagatt gcgttaattg
     8941 gcccgaacgg ctgcggtaaa accacgctac tgaaactgat gctgggacag cttcaggctg
     9001 acagcgggcg catccacgta ggaacgaagc tggaagtcgc ctacttcgat cagcatcgcg
     9061 ccgaactgga cccggaaaaa accgtgatgg ataaccttgc ggaaggcaag caagaggtga
     9121 tggtaaacgg taagccgcgc catgtactgg gctatttgca ggacttcctg tttcacccca
     9181 aacgggcgat gacgcccgtc cgcgcgcttt ccggcggcga acgtaaccgt ctgctgctgg
     9241 cgcgactgtt cctcaagccg agcaatcttt taattctcga tgaaccaacg aacgatcttg
     9301 acgtcgaaac gctggaacta ttagaagaat taattgatgg ctatcagggc acggtactac
     9361 tggtcagcca tgatcggcaa tttgtcgata ataccgtgac ggaatgctgg attttcgagg
     9421 gcggcggcaa aatcggacgt tatatcggcg gctaccatga tgcgcgtgcg cagcaagagc
     9481 agcatctggc gacgaaacag ccgatgacga aaaaaaatga ggaagttatt gcccctaaag
     9541 cagaaattgt aaaacgtggc agtagcaaac taagctataa actgcagcgc gagctggagc
     9601 agttacccgg tcagcttgaa gacctggaag cgaagctgga agcgctacag gcgcaggttg
     9661 cggatgcggc cttttttagc caaccccatg agcaaacgca gaaagttctg gccgatttaa
     9721 gtcaggcgga gcaagaactt gagcaagcct tcgaacgttg ggagtatctt gaaggcctga
     9781 aaaacggggc ataacgaaag gagcgcctat gtgtgaacat caccatgctg cgaagcacat
     9841 attgtgcccg caatgcgaca tgctggtggc tttaccccgc ctctcgcatg ggcaaaaagc
     9901 agcatgtcca cgatgcggcg caacgttaac gaccgagtgg gacgcgcccc ggcagcgtcc
     9961 taccgcctat gcgttagcgg cactatttat gttgctgctt tctaaccttt ttcccttcgt
    10021 gaatatgaat gtcgcgggcg tcaccagcga agtcacgctt ctggaaatcc ccggcgtcat
    10081 gttttctgaa gattacgcca gcctcggcac gttcttttta ttatttgtcc aactggtgcc
    10141 ggcattttgc ctggtgacca ttctattact tgtcaaccgc gccagtctgc cgttgtcggt
    10201 aaaaaaaacg ctggcaagga tctttttcct cctcaaatcg tggggaatgg cggaaatatt
    10261 tctcgccggg gtgttggtca gttttgttaa gctgatggct tacggcgata tcggcatcgg
    10321 cagcagcttt attccctggt gcttattttg tctcgttcaa ctgcgggcgt tccagtgtgt
    10381 cgatcgccgc tggttgtggg atgatatcgc cccgcaacct gcactggcgc agccgttaac
    10441 gccggggatt accggtatcc ggcagtcttt gcgttcttgc gcctgctgta cggcgatcct
    10501 gcctgcggag agtctcgtct gtccgcgttg ccatacgaaa ggctatgtcc ggcgtaaaaa
    10561 cagtttgcag tggacgctgg cgttattatt tacctcgatc atgctttatc tgcccgccaa
    10621 tatattgccg attatgatta ctgacttact gggctcgaaa atgccgtcga ccattctggc
    10681 tggcgtgatt ttgctgtgga gcgaggggtc ttatccagtg gcggcggtta tctttcttgc
    10741 cagtattatg gtgccgacgc taaaaatgat cgccattgcc tggctttgtt gggatgcgaa
    10801 aggccacggt aagcgcgaca gtgaacggat gcattttatt tatgaagtag tggagtttgt
    10861 ggggcgctgg tcaatgattg atgtctttgt cattgccgta ctctctgcgc tggtgcgtat
    10921 gggagggtta atgaatattt atcctgcgat gggtgcgttg atgtttgctt tagtcgtcat
    10981 aatgacaatg ttttctgcga tgacctttga tccgcgtctg tcgtgggatc gtgaatacga
    11041 accaggccat gaggagtcct gatagcatgg aacctaaaaa aggggaagcc aaagtacaaa
    11101 aggtgaaaaa ttggtcgcct gtctggatat tcccgattgt tactgcgctt atcggagcct
    11161 ggattctgtt ttatcactac agccaccagg gaccggaagt taccttaatt accaccaatg
    11221 cggaaggcat tgaaggcgga aaaacgacga tcaaaagtcg cagcgtggat gtcggcgtgg
    11281 ttgaaagcgc gacgctgact gacgatctga cccacgtaca aatcaaagcg cggcttcatt
    11341 ccggtatgga aaagttgctg cataaagact cggtattttg ggtcgtaaaa ccgcaggtgg
    11401 ggcgtgaagg cataagcggg cttgggacgt tgttatcagg cgcgtatatt gaactacaac
    11461 caggaagtaa gggcagtcag ccggaaagct atcagcttct tgactcaccg ccgttggcgc
    11521 cgcccgatgc caaaggtatt cgtgtgattc tggacagcaa aaaggccggt cagctcagtc
    11581 ctggcgatcc cgttctgttc cggggctatc gggtagggtc cgttgaaacc agctctttcg
    11641 atccgcaaaa acggacaatg agttatcagt tgttcattaa ggcgccaaac gatcgattgg
    11701 tcaccagtaa tgtccgattc tggaaagata gcggtatcgc tgtggatctg acatcggcgg
    11761 gaatgcgcgt ggaaatggga tcgttgacga cgttatttgg cggcggcgtg agttttgatg
    11821 tgccggaagg acttgagcag gggcaacccg tcgccgaaaa aacggcgttt aatctctacg
    11881 acgatcaaaa aagtattcag gattcgctgt acaccgatca tatcgattac ctgatgttct
    11941 ttaaagattc ggtgcgcgga ttacaacccg gcgcgccgct ggagttccgc ggtattcgtc
    12001 tggggacggt aagcaaagtg cctttctttg cgtctaatat gcgtcaggtg tttaacgacg
    12061 attaccgtat tcctgtgctg gtgcgcattg aaccggagcg tctgaaagcg caactgggag
    12121 aaaatgcgga tgttggcgcg catttgacgg aactgcttaa gcgcggttta cgcgcttcgc
    12181 ttaaaaccgg taacctggtg accggggcgc tgtatgtcga tctggacttt tatcctaagg
    12241 agccgccgat taccggacta cgcgaatttg atggttatga aattattccc accgtcagca
    12301 gcggcctggc gcaaattcaa cagcgactgg tggaaacgtt ggataagatc aacaacctgc
    12361 cgctgaatcc gatgattgaa caagcgacca atacgctgtc tgaaagccag cgtactatgc
    12421 gtcggttgca aaccacgctg gataatatga acaagattac ctccagtcag tcgatgcagc
    12481 agcttccggc ggatatgcaa acgacgttac gcgaacttaa ccgcagtatg cagggcttcc
    12541 agcctggatc ggcggcgtat aacaaaatgg tggcggatat gcagcgtctc gatcaggtgc
    12601 ttcgtgagtt acaaccggtg ttgaaaactc tgaacgagaa gagcaacgcg ctggtatttg
    12661 aagcgaagga taaaaaagat cctgagccta agagggcgaa acaatgaaaa aatggctagt
    12721 cgtgataatg gcgttctggc tggcgtcatg tagttccggc ggagaaaata aaagctatta
    12781 tcagctcccg atagcgcaaa gcggtgtgca aagcaccgca agtcagggca accgtctctt
    12841 atgggtagag caggtttccg tacctgacta tctggcaggt aacggtgtgg tgtatcaaac
    12901 cagtgatgtc cagtatgtga ttgccaataa caatctgtgg gccagcccgc tggatcagca
    12961 attacgtaac acgctggtgg cgaatcttag cgcccggctt cctggctggg tcgtcgcttc
    13021 ccagccgttg ggaaccaccc aggatacgtt gaacgttacc gtaaccggat tccatggacg
    13081 ttacgatggt aaggttatcg tcagcgggga gtggttatta aaccacaacg gacaactgat
    13141 taagcggcct ttccatatcg aagccagcca gcagaaagat ggctatgatg agatggtcaa
    13201 agtactggca agcgcatgga gtcaggaagc ggccgctatc gcagatgaga taaagcgcct
    13261 tccctgagat aaaaataatg taaatttaac cgcttcaggt cgtgcgcctg aggcggtttt
    13321 tatttttgac gccggaaaaa tagttgttat ggctcacatt ttttgtacaa atgatttacc
    13381 gtatagctca caaatatgac attggtgtga attttgcgca ttgacgggcg atccatttag
    13441 aggtattcgt gtagtgtgat tgcacatttt gtaatcactg ttttcttttc caccagatac
    13501 aaatatgagg gaaacgaggc atgaggagac aaaaacgaga tcgcctggaa cgggcacatc
    13561 aacgtggata tcaggccggc atcgccggac gatcaaaaga aatgtgtccc tatcagacgc
    13621 tgaatcaacg gtcatactgg ttgggaggtt ggcgacaagc catggaggac agggcggtaa
    13681 tggcctgatt ctgtctcttt agaaaaagaa acctccgcag tgcggaggtt tcgcctttat
    13741 gggctttgca agcatgatac cgatagcgcg gaatatcaat tcaacactta gaacgcggaa
    13801 gtatcctgga acaaaccgac tttcaaatcg tgtgcggtat agatcagacg accatccacc
    13861 agaacctcac cgtccgccag gcccatgatc aggcgacggt ttacgatacg tttaaaatga
    13921 atgcgatagg tgactttcct ggctgtcggc agaacctgac cggtaaattt cacttcgccc
    13981 acgcccagag cgcggccttt gccttcgccg cccaaccagc ccaggtagaa tcccaccaat
    14041 tgccacatag catccagacc cagacaaccg ggcatcaccg gatcgccgat aaagtggcat
    14101 ccgaagaacc atagatccgg attgatatcc agctcggctt cgacatagcc tttgtcgaaa
    14161 ttgccgcccg tttcggtcat cttaacgacg cggtccatca tcagcatgtt cggcgcaggg
    14221 agttgcggcc ctttagcgcc aaacagttca ccacgaccag aggcaagaag gtcttctttt
    14281 gtataggatt cgcgtttatc taccatgttt tatgtaaacc ttattttatt gaagcacgca
    14341 ggatagctaa cacgtgtacg ctgaacaagt ccgatcagtt cggaataaaa gcgttcagcc
    14401 aacgtaatgg ccacgggaaa cgatgacggc cttcctgttg cgtcgcctgc gcgatacgct
    14461 cctggatagt ctgcatcaac gtcgtttgac cttcgccatc ccacaccaga tttaacagta
    14521 gcggtaaggc gtcggtcacg tcgtctaccg cccagatagt gaacttctct tctttaaccg
    14581 cttgcagcag ttcagattta agactgagat ggcggacatt ggcggcaggg ataatcacgc
    14641 cctgtttacc gtttaattcc cgctgctcgc agatggcgaa gaaaccttca attttttcgt
    14701 ttagcccgcc cactggttgc gcgcgaccaa actgatcgac cgagccggta atcgcaatat
    14761 tttgattcac tggcacattg gccagcgcgc tgatgagcgc acataattcc gccattgagg
    14821 cgctatcgcc atccacttcg ctgtaggact gctcaaaggt taacgaggca gagaagggaa
    14881 tttgttgctc cagctgcaac tccgacatca ggaaggcctg cataatcatc attcccttag
    14941 cgtggatatt tccgccaagt tcggccttgc gctcaatatc gttaaattcg ccatcgccga
    15001 tatgcacaac acagctaatt cgcgacggtt cgccaaaggc gcgcggatgt ccgggaaact
    15061 caatgacgga aagcgcattg atttgtccaa cgcgttcgcc ttcggtttca atcaggatct
    15121 gctcttgcag aatctcgcct tgcatccgct ccgccagaaa gccttctcgc cattcgcgtc
    15181 gggcaagcat cagactgagc gcttctgcgc cgcaggtatc gccttcgcat aaaggcgacg
    15241 cctccttaaa ctggcgggct atccacagtg ggcaaagagg cagcgtatcc tgttcgccgg
    15301 tatagcgcac agcctcgcgt atcaggacgg gccaggcgtc cggtgccgga gggggcaaat
    15361 tatcgcgtaa agcgatacgc gtcacccatt gacaccacag ggtcatagct tctgcgtccg
    15421 ctatctgtaa attgtcttca aattcactgt agatagcctg ttccgcgagc tccggttcca
    15481 tctcctgaaa atcagccagt gattcacgtt cgccaaccag aatcaccttc agtttgagcg
    15541 gcattgatgg cacggagacc ggtaatggac gcgactcgtc aaaggccacc cagtcaaaac
    15601 gctcgcggct aacgatggct ttcagacgca tccatagtaa cggctgcgcc agaagggttc
    15661 gtaaggaaat aatcagcacg ccgccgttcg cctgatgaac cagtcccggt tgcagggtaa
    15721 tgtcgccgtt atactgccgc aggcaaccaa agagctgttc ggcttcgacc cagtcagcgc
    15781 tgacgacttg tgtgacggtg gcaaagttgt cttgcgcatt ctgcgcggcg cggtaatgaa
    15841 cagtatgccc ggaaacgtca taatgtccgc cggttaattg tccggcatcg gtttgcagag
    15901 cgcggacggc atctgaaagt aaagtgagat actcttgctc ttcaggcgct ttagtcagca
    15961 taaaagagga tgatgcccac ggctgtataa gttgctcaag cgcaaattgc agtcgtggct
    16021 gagtatcact gagtaaggtg tcgttttcgt cagtcgcgtg tggctgtgca aatatctcct
    16081 gatagctttc gctatccgga accagatcac gccatgcaag tttcgtaatg gtcaaagttg
    16141 aggtttttta gtctgttgta aaagggggga ttatagccta acccgtcacg ctgcacacgc
    16201 ggaaagcgaa tgcaaagtaa tatgaagacg tgtaaccatt cacaggttcg agattctttt
    16261 cttcagatgg ctaaaaaact gatattctga taacagttac acggtaacat tgggatcaca
    16321 atgaaatatc aacaacttga aaatcttgaa agcggttgga aatggaaata tctggtgaaa
    16381 aagcaccgcg aaggggagtt gatcacccgc tacgtggaag ccagtgctgc ccaggaagcc
    16441 gtcaatttgt tgttggccct cgaaaatgaa ccggtgcggg taaatgtctg gatagacagg
    16501 catatgaatc ctgccttgct taatcggatg agacaaacca ttcgggcaag acgcaaacga
    16561 cacttcaatg cggagcatca gcatacgcgc aaaaaatcta tcgatttaga gtttatggtc
    16621 tggcagcgtc tggcgggcct tgcgcagcga cgcggtaaaa cattatccga aacgattgtg
    16681 caactgatag aagacgcgga gcataaagag aaatatgcca cgcaaatgac cacgttaaag
    16741 caggatttac aggcgttatt aggcaagaag taacgctgaa aggcgttgcc acccagacca
    16801 gagcaaaaaa ccccgcgaag cggggttttt tatcagacgg aaacttaagc ctgcggctga
    16861 gttaccacgt ctttaacgcc tttaacttcg atctctacac gacgatccgg agccaggcaa
    16921 tcgatcaggg cagcgcgagg tttcacgttg tcacaggtgt tgccggtaac cgggttagat
    16981 tcgcccatac cacgtgcgga gattttgtca gacggaatac ctttggagat caggtaatca
    17041 acaacagact gagcacgttt ttcggacaga ccctggttgt aagcgtcaga accgatacgg
    17101 tcagtgaagc ccagaacgac aacggaaccg tctttcggat ccaggttgct cagctggctg
    17161 tacagctgat ccagagcctg ctggccttcc ggcttcaggg tcgatttgtt gaagttgaac
    17221 agtacgtcag acttcagagt gaagtgcttg gtctgtactt ccggagccgg agccggtgcc
    17281 ggagctacta ccggagcagc ttcttgctgg ccgaaacggt aggaaacacc tacgctcagc
    17341 aggccgttgt ccggacgggt gccgatggtg ttggcatcac cgatgttgtt agtccactgg
    17401 tattccagac gggttgcgat ttcaggggtg atggcatact cgataccgcc cgcgaatacc
    17461 ggggaaacgc cggtgtcgtg gtctttagta gacgcgccgc cagggacgtt agacttggtg
    17521 tctgcacgcc ataccatacc acccagacgg gtataaacgt ccagatcgtc agtgattgga
    17581 taacccagtt tagcggtcaa ctgaacgccc tgagctttat aagcgccatt ggtgttgtcg
    17641 cctttgtacg gcatacggcc taaccagtcg tagcccattt caaagccaac gtacgggtta
    17701 acctggtaac caccaaaagc acctgcgccc agttggtttt catgagtcgg gccatcattg
    17761 tgaatgaagc cggtgtcatg gtactgagac cagcccagtt tagcaccagc gtaccaggtg
    17821 ttatctttcg gagcggcctg cgctacggta gcgaaaccag ccagtgccac tgcaatcgcg
    17881 atagctgtct ttttcatttt ttgcgcctcg ttatcatcca aaatacgcca tgaatatctc
    17941 caacgagata acacggttaa atccttcacc gggggatctg ctcaatagtt actctaccga
    18001 tatctacggc ttatgctgag cacccctggc gatgtaaagt ctacaacgta gttggaaact
    18061 tacaagtgtg aactccgtca gacatgtgaa aaaacatgac gggtatacac atcatttaac
    18121 agtttcggat gataaatcgt acagcaaaga ttgcggaaac cgcttctggc aagcgttctc
    18181 gcaaaaaaac gttagcactc aaaggagata cgttcgcgta aaaaaaagtc caggataaat
    18241 cctaatttta cttaatgata caaattagag tgaattttta gcccggaatg ctgtctcctg
    18301 ggtaaagcgt gcgcacgtac agggcgcatg ataaacccta ccgcattacc taccttcgct
    18361 gcttcaacca ggctggcatg ttcttcttct gtcagttctt cagtcatcca accaattacc
    18421 acgctgtaat ttcctgtacg caaagcgcgg atcatcgact ccagcgtatg acgaggcgca
    18481 agctggctaa tttgcatcac tttcgttaat ggcaaacctg aagactgtac ccattcacgg
    18541 ctgagctttt gctgcggcgt gagccagagc tgccagcgtg attgttggcc taactgacgg
    18601 agtaaaggca aaagcaggag ttgcgccatc atgggctggt cttcgtggta gacaacttca
    18661 ctgaccagtc ctgccgcggc attttccgta gcggtgcgcg cagcgttgtg ggtagtggta
    18721 ggaaatgacg aagaacgatt tgcataacct gaagtgtaca taatcaatcc agccctgtga
    18781 gttactgtat attcatacag tactcctgtg gcgatgaaag atcaactcta ttttcggaaa
    18841 ctgtctcgca atttttattc ttagtggcgt caaaaataaa aatcatcttg ctcgcggagt
    18901 ataagttgcc tattttcgtc attaacggat ccgttactgc aaatcattct tttactttat
    18961 gatttaaaag gaattttatg agagcactct cttatgacag gatctatgaa tcgcaagaat
    19021 atttggcctc tttggggacg atccagtatc gatctttatt cggtagctat agtctgactg
    19081 tggaggatac cgtctttgcg atggtggcta atggcgagct ttatctccgc gcctgtgaag
    19141 aaagcgtacc ctactgtgtg aagcatcccc ccgcctggct catgtttatg aaatgtggac
    19201 gtcccgttat gctcaactat taccgggtgg atgaaagcct gtggcgcgat cagcagcagc
    19261 tggtacgttt atcgaagtat tctcttgacg cggcaatgaa ggaaaaacac agccgtattt
    19321 tacagcacag actcaaagat ctccccaata tgaccttcca tctggaaaca ttgctcaatg
    19381 agtcagggat aaaggacgaa aatatgttac gcatactggg cgcgaaaatg tgctggttaa
    19441 ggttgcgaca aagcaatccc ttgctgacgg tgaaagtttt gtatgccctg gaaggcgcaa
    19501 ttgtcggcgt acatgaagcg gcgctcccgg cgagtcgtcg ccaggagctt gccgactggg
    19561 ctcattcgct tacggctggg taattaatgt agaagtcggc ggtgaaattt gccgttgcaa
    19621 gcgtccaatc tcgggcagta aggcaatgag caaaccaatt tgttgaacaa ccagaggttc
    19681 tttgctgtcc ggacgtgttt ccagcgactg aactcgctgc tttaaaccct ccagcgcctg
    19741 gtgtacgcgc tgttcgtctt ctggctgatg atgaagcgca tcatcaacgt agcagaccgc
    19801 gtcatccaga agccccaaca cgtccggatt gctgagcttt tcgcggtgcg cgccgagggc
    19861 ggagatatag ctggtaaaag tgtgattgag gcaaagcagc ctgaacgccg cctcccgggt
    19921 ttcagccgtg acgtcgggtt cgctcgacat attagaaacc acggatgcca gttctgcatc
    19981 gcggttgtgc gcgtcgcgtc tggcaatgcg ataggccagg cggttatccc gtccctgatg
    20041 atattgctca aggatcgcat caaggtagcg gcaattagca tcggtggcgc gctggagtac
    20101 ccggggaagg ttgcgaaagc gccagtccgg ccaaataaag ctgaccgcag cccaggcgat
    20161 agcgcagcca attaacgtgt cgatgacgcg cggtaacgct acctcgaagc cttcgcccag
    20221 gaggttaaag cagagtaata ccagcagggt gatgaacatc gtcgcatggg catactgcac
    20281 attacggaat gcgaagaaaa gcacgccggt aatcaccagc agaactaact gtccttcaag
    20341 cgaagggaca aaccataaaa tcggcaggcc gatcgcaacg cctaccaacg taccgataat
    20401 cctgagcgca aggcgatggc gggtcgcgtt atagttaggc tgacaaacga acaggctggt
    20461 gagcaatatc cagtacccgt ggcgcatccc ggtaatttgg atgagagcat aaccgatgca
    20521 caataccagc gacatgcgta ccgcatggcg aaagagagcg gactccgggg taaaattacg
    20581 gctcagacgc agccagatgt cgctaaaccc gtgcaggcta tcgtcagcca actggttttc
    20641 tgactcattg cgcggcattg cctgggcctg ctccgactcg atcgtcgcca gttgcgcatc
    20701 aatagcgcgt aggttggtta ataagaatcc aagcgtattc agcagctcta aagaagcgcc
    20761 gctggcgcgc atacgttcaa gcgcggcgtc aatgtgggta aagacgcgtt caaagcgcgg
    20821 atcatgctgg tacggcgtac gcagtaagat acagcgcgcc agctgcgtac aggcctgcgc
    20881 ctgcatcgac atcagacgtt gaaagcggaa catgacgtcg ctatggcgaa aataatcgcg
    20941 cagcgtctgg tattgaatat gcgaagaact ggcgcgttca tgaatatcct gcgccacaaa
    21001 atagtaatgg agagtgcggc gcgtaccgcg ttgaccgcga tcgccgcgca ggcgagtcaa
    21061 caacgacact ttcgtttggt tcagcgtcgc cattaactgc ccgttcgcta acgctaaatc
    21121 atagagcggc gcctggcttt catcttcaat atcaggatca aacagacgtg atttcagttc
    21181 cagatagtgc gccaactgtt cgtaactgcg tgccagatta tcctgcaacg gacggatcgg
    21241 aaatagcaga tgcccggtta gcgtcagtag gttataccat actgcgcctg ccagcaggag
    21301 cagtggttgc tgataccagt gatcgtataa agaagcgccc agcatcgtat aaatcgcaat
    21361 gagtaacgcg ccgaacgcga tggtggcata gcgttgccct agtcctccca acagaataaa
    21421 tccgctggtg gataacgtta agcccaacgc aaatagccac ggccagggaa agagcagctc
    21481 cacagaagcc gacgcgataa aaaagcaaat taaggtaatg attaaattac gcaagcgtcc
    21541 ggcaaggcgg tcgtcgagat cggttagcgc cgcggcaacc ataccgagcg tgagcgggat
    21601 ggtcagtttg acgtcgccca gccaccaggg cagggcggtg gtgccgcaca gagcgataaa
    21661 aatgcggatg taatacagcc aggtactgtt ccaggtataa cggcgaatca acggacttaa
    21721 cataaaggct atttgtcccg atcattcaaa acggcggcgc gcgttagctt ctcgcgcggc
    21781 gcgagcggtt tctacagaga cgacgcggcg accgacaggc caaagcgcaa tcgcggcaat
    21841 tttaaagttc gcaataccga caggtatccc gatgatagtg acacactgcg cgataccgga
    21901 ggcaatgtgc atcaggcata gccaccagcc gaaaaaaagt aaccagaaaa tattcagcaa
    21961 ggtaccgcca gtattcatta atacgctttt tgccgccgga ttaagttcgt caacgtgaat
    22021 ggcttcatta ccgtaaggga acagggacag tttggttatc tcccagcagg agcgggtcaa
    22081 cggcagggta aaaataagca caatactgac cagcgtcgcc agcagccagg ccagcgtagt
    22141 ggcaaagccg cccagtacaa agtttaaaat attcagaacg gtacgcataa accctcagtt
    22201 cattccggtt ttctattact gcgggcaatt gtaacgtttt tttagactgg agcacgtttt
    22261 ctctggcggt tacactgata agcacatctt tacgtctgga ttcgctgagt catggaactg
    22321 aaagcaactt ctcttggaaa acgtctggcg caacacccgt atgatcgtgc cgtgatcctc
    22381 aatgctgggg tgaaagtgtc tggcgacagg catgaatatc ttattctatt caatcagtta
    22441 ttggcgattc actgtaagcg tgggctggta tggggcgagc tggagtttgt cctcccggag
    22501 gataaagtcg tgcgtttgca cggtaccgag tggtcggaaa cccagcaatt ccatcgctat
    22561 ctggacgcgc actggcgtcg ctggagccag gagatgagtg atgtcgccgc gcaggcatta
    22621 caggagcaat gggcgcgtat tagtgagcga acgggcggaa accaatggct tacccgtgaa
    22681 cacgttcgtg ggctggaaca cgaaattcgc cagacgtttg ccgccttacc gctgccggtc
    22741 tcacgtctgg aggagtttgc tcactgtcgc gagatatggc gtaagtgtct ggcatggtta
    22801 caggatagcg agggaagtcg gcagcagcat aatcaggcgt atgctgatgc catgctggaa
    22861 gcgcatgccg acttttttac gcagatagaa tcttctccgc ttaatccttc ccaggccagg
    22921 gcggtggtta acggcgaatc atcgttactg gtactggcgg gcgcgggaag cggtaagacc
    22981 tcggtgctgg tggcgcgcgc gggttggctg ttggcgcgcg ggcaagccga tgcggggcaa
    23041 attcttttac tggcgtttgg tcgcaaggcg gcagaagaga tggatgagcg tatccgcgag
    23101 cgcttacata cggaagagat tactgcccgt acgttccatt cgctggcgct gtatattatt
    23161 cagcaaggca gtaaaaaagc gccggttgtc agtaagctgg aaagtgacgc caccgcgcgg
    23221 catcagctat ttctgcacac ctggcgtcag cagtgtagcg agaaaaaagc gcaggccaaa
    23281 ggctggcgtc agtggctgga agaggagatg cagtgggtag tgccggaagg taatttctgg
    23341 gacgatgaga cattgcagcg gcgtctggcc cctcgcctgg atcgttgggt cagtttgatg
    23401 cgtatgcacg gcggcgcgca ggcagaaatg atcgctggcg cgccagagga gtgccgcgag
    23461 ctgtttggca aacgcattaa gttgatggcg ccgctgctga aggcctggaa aagcgcattg
    23521 aaagcggaaa atgccgttga tttctccggg ctgatccatc aggcaatggt gatcctcgaa
    23581 aaagggcgtt ttattagccc gtggaagcat attctggtcg atgaatttca ggatatttcc
    23641 ccgcaacggg cggcgctgtt agaggcgcta cgcaagcaga atagccagac tacgctgttt
    23701 gccgttggcg atgactggca ggcgatttac cgttttagcg gggcgcagct ctccttaacg
    23761 acggcgtttc atcagacgtt cggcgagggc gagcattgtc acctggacac cacgtaccgt
    23821 tttaacagtc ggattggcga tattgccaat cgctttgtac agcagaatcc gcaccaactt
    23881 aaaaaaccgt taaatagtct gaccccaggc gataaaaaag cggttacgtt attggatgaa
    23941 agccagttgg acgcgttact ggataaatta tccggctatg cgaaggagga tgaacgtatc
    24001 ctggtgctgg cgcgctatca ccatctgaaa cccgcgagtc tacaaaaagc ggcgactcgc
    24061 tggccgaagt tacagataga tttcatgact atccatgcca gcaaaggcca acaggccgat
    24121 tacgtgattc ttgtcggatt gcaggagggt aacgacggtt tccccgcccc ggcgcgagaa
    24181 tccattatgg aaagtgcgct ttttcctcag gttgaggatt ttccggacgc tgaagagcgg
    24241 cgtttgttat atgtggcgtt gacgcgcgcg cgtgcgcggg tctggctgct tttcaataaa
    24301 gataatccct cgcgctttgt ggaggcgctt aaacagctgg atgtgccggt ggcgaggaag
    24361 ccctaaagcg cgggcggtat agcatcccgc ccgcgtagcg gttatttcag gcgctcggcc
    24421 agataacgcg cataatccgg aataagaata tctacagcgt cattaaaatg cggggactgg
    24481 atgataaagt ccgccgttga gacattagtg gcgacaggga tattccatac agtggccaga
    24541 cgcagtagcg ctttgacatc ggggtcgtgc ggtaccgcgt taagcgggtc ccagaagaaa
    24601 atcaacacgt cgattttccc ttctgaaatg agcgcgccaa cctgctggtc gccgcccatc
    24661 gggccgctca gcatcgcatt aacgtccata ccggttgcgc gctggatcag attccccgtg
    24721 gtgccggttg cataaagaac gtgtttttcc agcaacggct gatggcgttc cacccagttc
    24781 attaacatct gtttgcagtg gtcgtgagca accaacgcga tatgtttgcg cgtcggcaag
    24841 gtgcgagtcg tcagttccat aattcgattc cgtagttaac ctgtctacag attactggaa
    24901 gcgcttgatg ctgcaagaga aagacaaaaa aattgcgcgc tgggacaact catatcaaga
    24961 gggcggctgt ttttccgccc attgcagaaa atgatggcgt gtctgcgggt cggccagtcg
    25021 gaaccaatat ttcagccgct gttctgtcag agtttgtgat tgcggcggta cggtatcaag
    25081 ctctgagacg tcggaaagta atgtgctgtc gtctgccatc atcgtggcga actgaggaag
    25141 cgaggcgcgt ttcgccgatt tattataacg ctcggtctct atttcgtaat cgaccacttt
    25201 agccgtagaa gtaatggcca gaatatcgag ttttaccgga atgggcatgg cgtcgccgtc
    25261 caaaagcgcc agacgcggcg ccgcgttaaa atgcgaggct tcgcgctcgt tttccagccg
    25321 cgggagctga aaattgacct gacttatcag ctgggtatcg aagcttatca ccagcggcgg
    25381 agaaatataa agccgctctt cattaccggg caggcggatg gttttttcca cccggaaaac
    25441 gagttgatgc ggcccgtttt ccagttcgat gctctctgcg ccgcgtaata aagagctgga
    25501 cacctttttg ccgtccagca ccagcagatc aacctcatta gacaaacgga gcgttgtggc
    25561 aaaaacagtc accggcaaac agagagcaag gaaggtggct agcgcgccgg ttttcataag
    25621 gttctcctgt ccaaaggccg tctggctaat aatgcatcga aatttttctt agatcatgtt
    25681 tactaacata tagacatatt ttggcgtttt gctctcatac atcggtatgg gatgaatggt
    25741 tgctatgtca ggtttgtcgt acactttgca aaacagccag gagaaagatg atgaaagaga
    25801 ccgatattgc tgatgttttg acgtccactc gcactatcgc gctggtaggt gcgagcgata
    25861 aacccgatcg tccaagctat cgggtaatga aatacctgct tgaacagggc taccatgtga
    25921 ttccggttgc gccaaaagtc gcgggtaaga cattgctggg gcaacagggg tatgccacgc
    25981 tggcggatat tcccgaaaaa gtcgatatgg tggatgtttt tcgcaactct gaagctgcat
    26041 ggggcgtcgc gcaggaagct atcgccatcg gcgcaaaaac gctgtggcta cagcttggcg
    26101 tgatcaacga acaggcggcg gtactggcgc gggatgcagg catgactgtg gtgatggatc
    26161 gctgcccggc gattgagatc cctcgcctgg ggctggcgaa ataaaagttt aaatggccgg
    26221 atatcgctct ccggcctttt acatacaatc agttacgtag tcgcggcgcc tgaagctgct
    26281 tgcgaatggt acgcgccagt tcatccatcg atggctgttc tggatgctcg tcccgcattt
    26341 cgcttcgcaa ctgggcctcg gccagataag tatgcactgg ctgaccatca tcatcttcca
    26401 ttaccacgtg gtaccacgga gcggcgcgaa gttcgtcgtt aaccgccagt tcatcaggcg
    26461 acggctcatc aagcgaatat tccgggtcga tatcgacgac cactccgagg taacctaaca
    26521 gggaatggcg gacctgttgg ccgataccga atttgctggc tatcatagtc acctcccggg
    26581 aaatagatac cctttatatg aggatactat tccacttttc aagttacatg acgcgacagg
    26641 caaacccttt cagatacagc ccttccgggt aggtggcgat caccgggtga tcggcggcct
    26701 gacggaactg ctctataaat tgtacatcac gaccggcatc tattgcggca tcggcaatga
    26761 ttttctgaaa taaatcgctg gtcatcagtc cggagcaaga gaatgtcagc agtatgccgc
    26821 ccggattgag cagttgaatc gctaacatgt taatgtcttt atagccccgg caggcgccca
    26881 ttaactggct tttattttcg acgaatttgg gcgggtccat gatgatgacg tcgaattttt
    26941 cgccgtgttc acggtaagcg cgcagcaact taaacacgtc gtcgcgcacg aattcggctt
    27001 tgctcaagtc cagttggttc agttcaacgt tttgcctggc gatatccagc gcatcctgtg
    27061 aggtatccac gctgacaacc tggcgacaac cacccattaa cgccgacacg gcaaaaccgc
    27121 cggtataaga gaagcagttc agtacccgct gattttctac gtagcggcgc gtcaccagac
    27181 gactgtcgcg ctgatcaaga taataaccgg ttttgtggcc gccctgtata tcgaccagca
    27241 atttcatacc gtgttcttca attggcaaaa gcgcaggcgg cagttcgcca gtgaccgggc
    27301 cttgcgtcag cgccatccct tcttttttcc gcacggcgac gtcgctgcga tcgtaaatag
    27361 cgcaatccgg atagcatgtt tgcagagcgc taattaatgc ggcgcgttga tattcggccc
    27421 cggcgctgag cagttgcagc accaaaaaat gaccaaaacg atcgatagtg acgccaggca
    27481 ggccatcgga ttcaccggcg atcagacgat agctatccag accgtctttt ttcgccagcc
    27541 agtcgcgcca ctgctgcgcc tggcgcaggc ggcgggtgaa aaacgcaata tcaatggatt
    27601 ctgttttatc aaatgtccag acgcgcgcgc ggatctggga ggctggcgac caggcgccgc
    27661 gtgctaacca ctttccctga tggtcgacga tatcgatagt ttcaccgagg ttggctttgc
    27721 cttccagacg ggatacggcg ccggaaaaga cccatgggtg gcggcggagt aaagattttt
    27781 ctcgcccttt gctgaggact aaacggggat attgcggaaa tgtagattca gtcatgcgga
    27841 gtaacctctc acaaacagtg acgcgagccg gatgatagtt ccagccaggg accgtgaaaa
    27901 cgaaatggcg cgtagggtag cacagatgag aggggcaatc accagcgtat ggcggtgagc
    27961 gtttctgcac aaaatagaat cgtaaaggca cagtttcttc agcggacgct ttttatagtg
    28021 ttatttcttt acatgaagaa ggaaatacaa tgaaaacagt cttctctttg accgcagccg
    28081 caatgatggc attgagtggc ggcgtatctg ccgcgtcggc gtttagcctc agtagcgcgg
    28141 atattccggc agattttcgt ttaacgcaac agcacgtctt taaaggattt ggttgtagcg
    28201 gagaaaatat ttcgccgcag ctgagctggc gcaatccgcc tgccggaacc aaaagctacg
    28261 ctattaccgt cttcgatcct gatgctccca ccggaagcgg ctggtggcac tggacgatgg
    28321 tgaatattcc tgcgcagatt cacgacctgc cgacgggggc tgataaaaaa cgttacccgc
    28381 tggagtggtg cagggacgga atgatttcgg ttatgctggc tttggcggcg cctgtccgcc
    28441 gccgggcgat gagcctcatc gctatcagtt tactgtgtgg gcgctgaata cggcaacact
    28501 gccgctcgac agtgagtcga gtggcgcgtt ggtagggttt atgcttaacg cgcatgtgat
    28561 tgcgaaagca caattcacgg ccacatacgg aaggtaaaac agaggacggc acggtgcagg
    28621 agatgcatat tcgacatcag gatcttacga cggcagaggt gcgttccagt catctgcacc
    28681 gtttgcatcg tgttacgctt ttttccgccg cgatctgcca tattacgcag ggcagtaaag
    28741 tcatcattca ggatgatagc cgccttgtcg ccgggcctgg cgagttaatt attattccgg
    28801 cgaacacgcc gctgg
//
LOCUS       DAJVBX010000030        27957 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.030, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000030 DAJVBX010000000
VERSION     DAJVBX010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 27957)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27957)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27957
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.030"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            18..1007
                     /locus_tag="OPV72_001184"
     CDS             18..1007
                     /locus_tag="OPV72_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001671655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiiG family protein"
                     /protein_id="HCR9913545.1"
                     /translation="MTAGLSACDEKKADEQPVAQSADSSASNTQSTSAESADANDVLN
                     QKLNVYIDCYNNLQADIYRAVNRYANTFDDFRTGPTGKEDDPSPLVPVYPAFIQDCRK
                     DIKAAAELKPAFASLDSAALAFINAAGPLAETINSMNKYYDQDNFKDDAFAGAKAFHK
                     TFIKQFDEFDPIAKKYIAEITIMSKQHAANEIKATEKKEGKSIKYYTLLTMQEAETLN
                     DAVADASFDVAAVSKQLADFEEHTQKLNEKINVDIDKHRSFPGFISELEKFQGKVKKR
                     IRRVRDNVAYTSHEQDYLNSGSGDMVDGSYKAVVKAYNELIDTYNGYHLEREF"
     gene            complement(1283..2119)
                     /gene="fdhD"
                     /locus_tag="OPV72_001185"
     CDS             complement(1283..2119)
                     /gene="fdhD"
                     /locus_tag="OPV72_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HCR9913546.1"
                     /translation="MNNILSEEVLNVTDFTTSRQLTLWKREDLQSSQLDDVAEEVPVA
                     LVYNGISHVVMMASPKDLTHFAMGFSLSEGIIDSPREIYGMDVVPSCNGLEVQIDLSS
                     RRFMGLKARRRALAGRTGCGVCGVEQLNDIGKPVQPLPFSQTFNLGNLDRALKHLNDF
                     QPTGKLTGCTHAAAWVMPSGELAGGHEDVGRHVALDKLLGRRATEGEEWRQGAALVSS
                     RASYEMVQKSAMCGVEILFAVSAATTLAVDVAERCNLTLVGFCKPGRATIYTHPQRLI
                     AD"
     gene            2314..5364
                     /gene="fdnG"
                     /locus_tag="OPV72_001186"
     CDS             2314..5364
                     /gene="fdnG"
                     /locus_tag="OPV72_001186"
                     /EC_number="1.17.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:2899..2901,aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase-N subunit alpha"
                     /protein_id="HCR9913547.1"
                     /translation="MQVSRRQFFKICAGGMAGTTAAALGFAPGVALAETRQYKLLRTR
                     ETRNTCTYCSVGCGLLMYSLGDGAKNAKASIFHIEGDPDHPVSRGALCPKGAGLVDFI
                     HSESRLKFPQYRAPGSDKWQQISWEEAFDRIAKLMKEDRDANYQAQNAEGVTVNRWLT
                     TGMLCASASSNETGYLTQKFSRALGMLAVDNQARVUHGPTVASLAPTFGRGAMTNHWV
                     DIKNANLVVVMGGNAAEAHPVGFRWAMEAKIHNGAKLIVIDPRFTRTASVADFYAPIR
                     SGTDIAFLSGVMLYLLTNEKYNREYTEAYTNASLIVREDFGFDDGLFTGYDADKRQYD
                     KTSWHYELDENGFAKRDTTLQHPRCVWNLLKQHVSRYTPDVVENICGTPKADFLKVCE
                     YIAETSAKDKTASFLYALGWTQHSIGAQNIRTMAMIQLLLGNMGMAGGGVNALRGHSN
                     IQGLTDLGLLSQSLPGYLTLPSEKQTDLQTYLAANTPKPLLKDQVNYWGNYPKFFVSM
                     MKAFFGDKATAENSWGFDWLPKWDKGYDVLQYFEMMKQGKVNGYICQGFNPVASFPNK
                     NKVVASLSKLKYLVTIDPLNTETSTFWQNHGESNDVDPSKIQTEVFRLPSTCFAEENG
                     SIVNSGRWLQWHWKGADAPGIAMTDGEILAGIFLRLRKMYSEQGGANPEQVLNMTWNY
                     TKPYEPASEEVAMESNGKALADLIDPATGAVVVKKGQQLSSFAQLRDDGTTSSGCWIF
                     AGSWTPEGNMMARRDNADPSGLGNTLGWAWAWPLNRRILYNRASADPQGNPWDPKRQL
                     LKWEGGKWAGWDIPDYSAAAPGSDVGPFIMQPEGMGRLFAIDKMAEGPFPEHYEPFET
                     PLGTNPLHPNVISNPAARIFKDDADALGKADKFPYVGTTYRLTEHFHYWTKHALLNAI
                     AQPEQFVEIGEKLANKLGIAHGDTVKVSSNRGYIKAKAVVTKRIRTLKADGKDIDTIG
                     IPIHWGYEGVAKKGFIANTLTPFVGDANTQTPEFKSFLVNVEKV"
     gene            5377..6279
                     /gene="fdxH"
                     /locus_tag="OPV72_001187"
     CDS             5377..6279
                     /gene="fdxH"
                     /locus_tag="OPV72_001187"
                     /EC_number="1.17.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase subunit beta"
                     /protein_id="HCR9913548.1"
                     /translation="MAYQSQDIIRRSATNGFTPAPQARDHQEEVAKLIDVTTCIGCKA
                     CQVACSEWNDIRDEVGNNVGVYDNPADLTAKSWTVMRFSEVEQNDKLEWLIRKDGCMH
                     CADPGCLKACPAEGAIIQYANGIVDFQSEQCIGCGYCIAGCPFNVPRLNPEDNRVYKC
                     TLCVDCVVVGQEPACVKTCPTGAIHFGSKEDMKTLAGERVAELKTRGYDNAGLYDPAG
                     VGGTHVMYVLHHADKPNLYHGLPENPEISETVKFWKGVWKPLAAFGFAATFAASVFHY
                     VGVGPNRAEEEDDNLHEEKDEVRK"
     gene            6276..6911
                     /gene="fdoI"
                     /locus_tag="OPV72_001188"
     CDS             6276..6911
                     /gene="fdoI"
                     /locus_tag="OPV72_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase cytochrome b556 subunit"
                     /protein_id="HCR9913549.1"
                     /translation="MKRRDTIVRYTAPERINHWIVAFCFVLAAVSGLGFLFPSFNWLM
                     HILGTPQLARILHPFVGVVMFASFIIMFFRYWHHNLINRDDIFWAKNIRKIVVNEEVG
                     DTGRYNFGQKCVFWAAIIFLVLLLVSGVIIWRPYFAPAFSIPVIRFALMLHSFAAVAL
                     IVVIMVHIYAALWVKGTITAMVEGWVTRSWAKKHHPRWYREVRKTTEKETE"
     gene            6908..7837
                     /gene="fdhE"
                     /locus_tag="OPV72_001189"
     CDS             6908..7837
                     /gene="fdhE"
                     /locus_tag="OPV72_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory protein FdhE"
                     /protein_id="HCR9913550.1"
                     /translation="MSIRIIPQDELGSSEKRTADMIPPLLFPRLKNVYNRRAERLREL
                     AENNPLGDYLRFAALIAHAQEVVLYDHPLEMDLTARIKEANDQGKPPLDIHVLPRDKH
                     WQKLLHSLIAELKPEMNGPALAVIENLEKASEQELEQMASALFASDFASVSSDKAPFI
                     WAALSLYWAQMASLIPGKARAEYGEARQYCPVCGSMPVSSMVQIGTTQGLRYLHCNLC
                     ETEWHVVRVKCSNCEQSRDLHYWSLENEQAAVKAESCGDCGTYLKILYQEKDPKVEAV
                     ADDLASLVLDARMEQEGFARSSINPFLFPGEGE"
     gene            complement(7875..8249)
                     /locus_tag="OPV72_001190"
     CDS             complement(7875..8249)
                     /locus_tag="OPV72_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system VapC family
                     toxin"
                     /protein_id="HCR9913551.1"
                     /translation="MVKGSALFDTNILIDLFSGRIEAKHALEAYPPQNAISLITWMEV
                     MVGAKKYHQENRTRIALSAFNIIGVTQEIAERSVIVRQEYGMKLPDAIILATAQVHRC
                     ELVTRNTKDFADIPGVITPYHL"
     gene            complement(8249..8491)
                     /locus_tag="OPV72_001191"
     CDS             complement(8249..8491)
                     /locus_tag="OPV72_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005224335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HCR9913552.1"
                     /translation="MMAGMDMGRILLDLSDDVIKRLDDLKVQRNLPRAELLREAVEQY
                     LERQDRAETTISKALGLWQGCEEDGVEYQRKLREEW"
     gene            8696..9625
                     /locus_tag="OPV72_001192"
     CDS             8696..9625
                     /locus_tag="OPV72_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCR9913553.1"
                     /translation="MALESGIAQLVEEFIAAGRPSSREQNIDDRRAGYIASTTLAGET
                     ETRVQVEDIELDAMTFRVVSPLNATGKLPCIIYYHGGCFVSGGFATHDNQLRQLAFYS
                     RCRVIAAQYRLAPEHTFPAAHNDAETGANTIWKYAQKLGIDRENITLAGDSAGGHLAL
                     VTALRLKAARQWQPAQLILIYPMLDATARFASYTCNGLDYIITRDTLLSGYEMYMPRT
                     DPLHPEASPLWREDFAGLPSTHIITAEFDPLRDEGEALYQRFQEQGVECTCQRYLGVI
                     HGFFQLGGVSKTARDAIRDVAWRVVSPSTSKMT"
     gene            9711..10022
                     /locus_tag="OPV72_001193"
     CDS             9711..10022
                     /locus_tag="OPV72_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HigB family
                     toxin"
                     /protein_id="HCR9913554.1"
                     /translation="MHVISRKLFNEAMLMYPNHELALTELLNVLEKKTFTQPEEMKRY
                     IPSLDNFKYRDKWWVIDVSGNSLRLISYIDFRLHKIFVKHIVSHAEYDKLTAYYRGNE
                     E"
     gene            10019..10465
                     /locus_tag="OPV72_001194"
     CDS             10019..10465
                     /locus_tag="OPV72_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462910.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HigA family
                     antitoxin"
                     /protein_id="HCR9913555.1"
                     /translation="MRTHRQMDATSAKKIVDTFSDAVKSVPLMGEDRNDNEYRRALAL
                     VEFLVDHDDLENPLFELLCARISEYEKHAPEFKALNQHLEKTPPGVSVLRTLMDQYGL
                     KAADLANELGSKSNVSNILNGRRALTVNHIKALTQRFKLPADAFIE"
     gene            complement(10480..11421)
                     /gene="fabY"
                     /locus_tag="OPV72_001195"
                     /gene_synonym="yiiD"
     CDS             complement(10480..11421)
                     /gene="fabY"
                     /locus_tag="OPV72_001195"
                     /gene_synonym="yiiD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001666856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid biosynthesis protein FabY"
                     /protein_id="HCR9913556.1"
                     /translation="MYHLRVPQTEEELERYYQFRWEMLRKPLHQPKGSERDGWDALAH
                     HQMVVDEEGNLVAVGRLYINADNEASIRFMAVHPSVQDKGLGTLMAMTLESVARQEGV
                     KRVTCSAREDAVEFFAKLGFVNQGEITTPTTTPIRHFLMIKPVASLDDILHRGDWCGQ
                     LQQAWYEHIPLSEKMGVRIQQYTGQKFITTMPETGNQNPHHTVFAGSLFSLATLTGWG
                     LIWLMLRERHLGGTIILADAHIRYSKPISGKPNAVADLGSLSGDLDRLARGKKARVQL
                     QVELLGGETAGAIFEGIYIVLPAKPFGPYEEGGNEEE"
     gene            complement(11466..11903)
                     /gene="dtd"
                     /locus_tag="OPV72_001196"
     CDS             complement(11466..11903)
                     /gene="dtd"
                     /locus_tag="OPV72_001196"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HCR9913557.1"
                     /translation="MIALIQRVTRASVTVEDEVTGKIGPGLLVLLGVEKEDDEQKANR
                     LCERVLGYRIFSDVDGKMNLNVQQAGGSVLVVSQFTLAADTERGMRPSFSGGAAPDRA
                     QALYEYFVERCRQQAINTQTGRFAADMQVELVNDGPVTFWLQV"
     gene            complement(11900..12772)
                     /locus_tag="OPV72_001197"
     CDS             complement(11900..12772)
                     /locus_tag="OPV72_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor BrkB family protein"
                     /protein_id="HCR9913558.1"
                     /translation="MLKTVHQKAGRHTRPVRAWLKLLWQRIDEDNMTTLAGNLAYVSL
                     LSLVPLIAVVFALFAAFPMFSDVSIQLRHFIFANFMPATGDVIQRYIEQFVANSNKMT
                     AVGACGLIVTALLLMYAIDSALNTIWRSKRTRPKVYSFAVYWMILTLGPLLAGASLAI
                     SSYLLSLRWASDLNTVIDNVLRILPLLLSWISFWLLYSIVPTTRVPNRDALVGAFVAA
                     LLFEAGKKGFALYITMFPSYQLIYGVLAVIPILFVWVYWTWCIVLLGAEITVTLGEYR
                     KLKQAAEQEEADQP"
     gene            complement(12766..13365)
                     /gene="yihX"
                     /locus_tag="OPV72_001198"
     CDS             complement(12766..13365)
                     /gene="yihX"
                     /locus_tag="OPV72_001198"
                     /EC_number="3.1.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphatase"
                     /protein_id="HCR9913559.1"
                     /translation="MLYIFDLGNVIVDIDFNRVLGVWSDLSRVPLASLKQKFTMGETF
                     HQHERGEITDEAFAEAFCHEMALSLSYEQFAHGWQAVFVGLRPEVIAIMHKLREQGHR
                     VVVLSNTNRLHTHFWPEEYPEVRAAADHIYLSQDLGMRKPEARIYQHVLQKEGFSAAD
                     AVFFDDNADNIEGANQLGITSILVKDKATIPDYFAKLLC"
     gene            complement(13556..14359)
                     /locus_tag="OPV72_001199"
     CDS             complement(13556..14359)
                     /locus_tag="OPV72_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCR9913560.1"
                     /translation="MSLTELTGNPRHDRLLMLIDERGYMNIDELASLLEVSTQTVRRD
                     IRKLSEQGLITRHHGGAGRASSVVNTAFEQREISWTQEKKAIAEAVADYIPDGSTIFI
                     TIGTTVEQVARALLNHNHLRIITNSLRVAHILYNNPRFEVMVPGGTLRPHNSGIIGPS
                     AAAFVAGFRADYLVTSVGAIESDGALLEFDVNEASVVKTMMAHSRHILLAADHTKYHA
                     SAAVEIGNVSQITALFTDEYPGPALQNLLQSQQIEVVQVSPSLDDAVSA"
     gene            complement(14393..15289)
                     /locus_tag="OPV72_001200"
     CDS             complement(14393..15289)
                     /locus_tag="OPV72_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462904.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HCR9913561.1"
                     /translation="MVRIACVGITVMDRIYYVEGLPTEGGKYVAKRYTEVGGGPAATA
                     AVAAAKLGAQVDFIGRVGDDDTGNSLLAELESLGVNTRYTRRYTQAMSSQSAIMVDAK
                     GERIIVNYPSPDLLPDADWLNDIDFSQWDVVLADVRWHDGAKQAFTLARQAGVMTVLD
                     GDITPQDISELVALSDHAAFSEPGLARLTGMSEAIDALKKAQMLTNGHVYVTRGSEGC
                     NWLEKAAVRHQPGFTVEVVDTTGAGDVFHGALAFGLASGYAIEEAVRFASGVAALKCT
                     RPGGRAGIPDCEQTRSFLSLFV"
     gene            15454..16350
                     /gene="yihU"
                     /locus_tag="OPV72_001201"
     CDS             15454..16350
                     /gene="yihU"
                     /locus_tag="OPV72_001201"
                     /EC_number="1.1.1.373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfolactaldehyde 3-reductase"
                     /protein_id="HCR9913562.1"
                     /translation="MAVIAFIGLGQMGSPMASNLLKQGHQLSVFDINPDAVQRLVDKG
                     AQPASSPAQTTIGAEFVITMLPNGDLVRSVLFGEQGVCETLSREALVIDMSTIHPLQT
                     DKLIADMQSKGFSMMDVPVGRTSDNAITGTLLLLAGGTTEQVERATPVLMAMGNELVN
                     TGGPGMGIRVKLINNYMSIALNALSAEAAVLCEALGLSFDVALKVMSGTAAGKGHFTT
                     TWPNKVMKGDLSPAFMIDLAHKDLGIALDVANQLHVPMPLGAASREVYNLARAAGRGR
                     EDWSAILEQVRISAGLTANVKK"
     gene            16373..17251
                     /gene="yihT"
                     /locus_tag="OPV72_001202"
     CDS             16373..17251
                     /gene="yihT"
                     /locus_tag="OPV72_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfofructosephosphate aldolase"
                     /protein_id="HCR9913563.1"
                     /translation="MNNYTIKDITRASGGFAMLAVDQREAMRLMFAAAGAKTPVADSV
                     LTDFKVNAAKILSPYASAVLLDQQFCYRQAVEQNAVAKSCAMIVAADDFIPGNGIPVD
                     NVVIDKKINAQAVKRDGAKALKLLVLWRSDEDAQQRLDMVKEFNELCHSNGLLSIIEP
                     VVRPPRCGDKFDREQAIIDAAKELGDSGADLYKVEMPLYGKGARSDLLTASQRLNGHI
                     NMPWVILSSGVDEKLFPRAVRVAMEAGASGFLAGRAVWSSVIGLPDTELMLRDVSAPK
                     LQRLGEIVDEMMAKRR"
     gene            17267..18403
                     /gene="yihS"
                     /locus_tag="OPV72_001203"
     CDS             17267..18403
                     /gene="yihS"
                     /locus_tag="OPV72_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfoquinovose isomerase"
                     /protein_id="HCR9913564.1"
                     /translation="MKWFNTLSHNRWLEQETDRIFNFGKNAAVPTGFGWLGNKGQIKE
                     EMGTHLWITARMLHVYSVAASMGRPGAYDLVDHGIKALNGALRDKKYGGWYACVNDQG
                     VVDASKQGYQHFFALLGAASAVTTGHPEARKLLDYTIEVIEKYFWSEEEQMCLESWDE
                     AFSQTEDYRGGNANMHAVEAFLIVYDVTHDKKWLDRAIRIASVIIHDVARNNHYRVNE
                     HFDSQWNPIRDYNKDNPAHRFRAYGGTPGHWIEWGRLMLHLHAALEARFETPPAWLLE
                     DAKGLFHATIRDAWAPDGADGFVYSVDWDGKPIVRERVRWPIVEAMGTAYALYTLTGD
                     SQYEEWYQKWWDYCIKYLMDYENGSWWQELDADNKVTTKVWDGK"
     gene            18512..19368
                     /locus_tag="OPV72_001204"
                     /pseudo
     CDS             18512..19368
                     /locus_tag="OPV72_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462900.3"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aldose-1-epimerase"
     gene            19412..21448
                     /locus_tag="OPV72_001205"
     CDS             19412..21448
                     /locus_tag="OPV72_001205"
                     /EC_number="3.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HCR9913565.1"
                     /translation="MNSLPQRSTDFELTTSQDGFALSWQQRLILRHSAENPCLWIGAG
                     VADIDMFRGNFSIKDKLNEKIALTEATVSELPDGWLVQFSRGATISATLRISADEAGR
                     LTLDLQNDDLHHNRIWLRLAANPDDHIYGCGEQFSYFDLRGKPFPLWTSEQGVGRNKT
                     SYVTWQADCKENAGGDYYWTFFPQPTFVSTQKYYCHVDNSCYMNFDFSAPEYHELALW
                     EDKTTLRFECADTYIALLEKLTALLGRQPELPDWVYDGVTLGIQGGTEVCQQKLDTMR
                     NAGVKVNGIWAQDWSGIRMTSFGKRVMWNWKWNSDNYPQLDSRIKQWKEEGVQFLSYI
                     NPYVASDKDLCAEAARHGYLAKDATGGDYLVEFGEFYGGVVDLTNPEAYDWFKDVIKK
                     NMIALGCSGWMADFGEYLPTDTYLHNGVSAEIMHNAWPALWAKCNYEALQETGKLGEI
                     LFFMRAGYTGSQKYSTMMWAGDQNVDWSLDDGLASVVPAALSLAMTGHGLHHSDIGGY
                     TTLFDMKRSKELLLRWCDFSAFTPMMRTHEGNRPGNNWQFDGDAETIAHFARMTTVFT
                     TLKPYLKQAVAQNAATGLPVMRPLFLHYENDAATYTLKYQYLLGQDLLVAPVHEQGRC
                     DWTLYLPEDHWVNIWTGEAHHGGEITVDAPIGKPPVFYRAKSEWALLFASLRNI"
     gene            21494..22876
                     /locus_tag="OPV72_001206"
     CDS             21494..22876
                     /locus_tag="OPV72_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR9913566.1"
                     /translation="MSQTSSNPATIRLPFKEKLAYGLGDLGSNILLDIGTLYLLKFYT
                     DVLGLPGTYGGIIFLIAKFFTAFTDMGTGIMLDSRRKIGPKGKFRPFVLYAAFPVTLL
                     AIANFVGTPFEVTGKTVVATMLFMLYGLVFSMMNCSYGAMVPAITKNPDERASLAAWR
                     QGGATLGLLLCTVGFVPVMNLIEGNAQLSYIFAATLFSLFGLLFMWLCYAGVKERYVE
                     VKPVDSAQKPGLLQSFRAIAGNRPLFILCIANLCTLGAFNVKLAIQVYYTQYVLNDPI
                     LLSWMGFFSMGCIFIGVFLMPGAVRRFGKKKVYIGGLLIWVAGDLLNYFFGGGSVSFV
                     AFSCLAFFGSAFVNSLNWALVSDTVEYGEWRTGVRSEGTVYTGFTFFRKVSQALAGFF
                     PGWMLTQIGYIPNVVQSAGTVEGLRQLIFIYPCVLAVITIIAMGCFYNLNEKMYVRIV
                     EEIEARKHTV"
     gene            22922..24343
                     /locus_tag="OPV72_001207"
     CDS             22922..24343
                     /locus_tag="OPV72_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR9913567.1"
                     /translation="MSNHDPLTLKLSLREKCAYGVGDFGSNLMLCIGTLYLLKFYTDE
                     LGMPAYYGGIIFLVAKFFTAFTDMLTGVLLDSRRNIGAKGKFRPFILYASFPVALVAT
                     AQFFATHFTLPVKTAFATVLFMLFGLFYSLMNCSYGAMVPAITKNPHERAQLAAWRQG
                     GATIGLLLCTVGFMPIQALFTRSPSLGYLVAAVIFSVCGLFSMWWCFSGVKERYIETV
                     PDTHKPSILKSFCAIFRNPPLLVLCVANLCTLAAFNIKLAIQVYYTQYVLNDIHLLSW
                     MGFFSMGCILIGVLLVPDAVKRFGKKQVYLGGLILWAVGDILNFIWGGTSFLFVIFSC
                     IAFFGTAFVNSLNWALVPDTVDYGEWKTGIRAEGSVYTGYTFSRKISAALAGFLPGIM
                     LTQIGYIPNIAQSDTTLLGLRQLIFLWPCGLAIIAALTMGFFYKLNEQRFAFIIEEIA
                     QRKKTGNQIVATNNKQSISTVNN"
     gene            24411..25103
                     /gene="ompL"
                     /locus_tag="OPV72_001208"
     CDS             24411..25103
                     /gene="ompL"
                     /locus_tag="OPV72_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpL"
                     /protein_id="HCR9913568.1"
                     /translation="MKSLNTLVILTSVISTSVFAGAYVENREAYNLASDQMEFMLRVG
                     YNSDMGAGIMLTNTYTLQRDDELKHGYNEIEGWYPLFKPTDKLTIQPGGLINDKSIGS
                     GGAVYLDINYKFTPWFNLTVRNRYNHNNYSSTDLNGELDNNDSYEIGNYWNFIITDKF
                     SYTFEPHYFYNVNDFNSSNGTKHHWEITNTFRYRINEHWLPYFELRWLDRNVGLYHRE
                     QNQIRIGAKYFF"
     gene            25260..26108
                     /locus_tag="OPV72_001209"
     CDS             25260..26108
                     /locus_tag="OPV72_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STM4015 family protein"
                     /protein_id="HCR9913569.1"
                     /translation="MNKRFNIDWDNELTQEQLINLILTDEDLPKLRSLTIGNWGDCWE
                     DETCQPIIDMIVENAPRFSHLESLFIGDMESEDCEISWIKQGDYSRLYAALPNLKELI
                     IKGASDLRLGAIHHEKLEHLEIISGGIPSNVLAELQNAQLPALKTLKLFLGVEEYGFD
                     GSLDNVMALVSKDLFPQLNHLGLMNSEEQDDIARRVLESNILPQLNVLELSCGTLTDS
                     GAEALLEHKDRIAHLETLDLHHHYLTPEMQEKLKAALPIPLNLSEALEPDDYDGDIYM
                     NAMYTE"
     gene            26121..27146
                     /locus_tag="OPV72_001210"
                     /pseudo
     CDS             26121..27146
                     /locus_tag="OPV72_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462894.3"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="STM4014 family protein"
     gene            27139..>27957
                     /locus_tag="OPV72_001211"
     CDS             27139..>27957
                     /locus_tag="OPV72_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462893.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STM4013/SEN3800 family hydrolase"
                     /protein_id="HCR9913570.1"
                     /translation="MYNSMDEVPVSLHASIDTGDGEFDMNALISNNAHILFIVLDSLR
                     YDIALQEQTAGNTPNLNHYGQWTKCEAAGNFTWPSHHAMFSGFMPKPIDDTVNQTMLL
                     FPKDIGLGRKGPKNAFAFDDATWIKSLENKGYQTICIGGVSFFNNRSGMGKVFPSMFK
                     ESYWHPRFACTVKESMDNQIHYIQKIMAERAGSQPVMMYINIDTIHYPNHFYVEGAAP
                     GDTVETHAAALRYIDARIDGLLNIFRQTGGETFVIVCSDHGTCYGEDGKYFHSFN"
BASE COUNT         6852 a         7317 c         7212 g         6576 t
ORIGIN      
        1 ttattatcgc tatgctgatg actgccgggc taagcgcttg tgatgaaaaa aaagcggacg
       61 aacaacctgt agctcagagt gcggattcat cagcgagcaa tacacaatcc acatcagcgg
      121 aaagcgcaga tgcgaacgat gttcttaacc aaaagctgaa tgtttacatt gattgttata
      181 ataatctcca ggcagatatt taccgtgctg taaatcgtta tgctaacaca ttcgacgatt
      241 tccgcaccgg tcctaccggt aaggaagacg atccctctcc gctggttcct gtgtatcctg
      301 catttatcca ggactgccgg aaagacatca aggcggcggc tgaattaaag ccggcgtttg
      361 cctctctgga tagtgctgct ctggcattta ttaatgcggc tgggccacta gctgaaacaa
      421 tcaatagtat gaataaatac tatgatcaag ataacttcaa ggatgatgcc tttgctggcg
      481 ctaaagcgtt ccataaaacg tttataaaac agttcgatga gtttgatccc attgcgaaaa
      541 aatatatcgc cgagattacc attatgagta agcagcatgc ggctaatgaa attaaggcga
      601 ccgagaagaa agaaggtaaa tccattaagt actatacgct tttgacgatg caggaagccg
      661 agacgcttaa tgacgctgta gctgatgctt cttttgatgt ggcggcagta agcaaacagc
      721 tcgctgattt tgaagagcat actcagaagc taaacgagaa gatcaacgtt gatatagata
      781 aacatcgtag cttccctggt tttatttctg agctggaaaa attccagggc aaggtgaaaa
      841 aacgcattcg gcgcgtgcgc gataacgtgg cgtatacctc gcatgagcag gactacctca
      901 atagcggcag cggcgatatg gtagatggtt cttataaggc tgtggttaaa gcttataacg
      961 agctcatcga cacctataat ggctatcatc ttgagcgtga gttctaagct tttcacgctg
     1021 caaatcgcgt gcatatgacc gctgaactga gcaaataagt cgttaccgac tgtcgaaaga
     1081 gcgccccagg ggcgcttttt tcgttcgaag tattaccggg tagcaagcgc ctcgttaatg
     1141 actggaataa gctgcggtcc agcttaaaaa cgattaaaac ctgtatggcc tcgccactat
     1201 acgtgtatac gtgattccgt tatcaagaga ggctgtaaaa ttgagaaaat atatatttta
     1261 cgaaaatgta gagggtacta ttttagtctg cgattaaccg ctgcggatgg gtataaatcg
     1321 tcgcccgacc cggcttacag aaccccacca gcgtaagatt acaccgttca gcgacgtcaa
     1381 ccgcgagcgt ggtagcagca gaaaccgcaa acaaaatttc cacaccgcac atcgccgact
     1441 tctgcaccat ttcgtaactc gcacgactgg aaaccagcgc cgcgccttgc cgccattcct
     1501 caccttccgt agcgcggcgg ccgagcagtt tatccagcgc aacgtggcgt ccgacatctt
     1561 catggccccc cgccagttca cccgacggca tgacccacgc cgcagcgtgc gtacaacccg
     1621 tcagcttacc cgtcggttga aaatcattca gatgttttaa cgcgcgatca aggttaccga
     1681 gattaaacgt ttggctaaac ggcagcggtt gcaccggctt accaatgtca ttgagctgtt
     1741 ccacgccaca cacgccgcaa ccggtgcgtc cggccagcgc gcgacgacgc gctttcagcc
     1801 ccataaatcg acggctggaa agatcaatct gcacttcaag tccgttacag gacggcacaa
     1861 cgtccatgcc atagatttca cgcgggctgt caatgatccc ttccgacaga gaaaacccca
     1921 ttgcgaaatg cgtcagatct ttcggagagg ccatcataac gacatgcgaa atgccgttat
     1981 acaccagtgc cactggcact tcctcggcaa catcatcaag ttgggaggac tgcaaatcct
     2041 cgcgtttcca gagtgtcaac tggcgtgagg ttgtgaaatc agtcacattt aggacttctt
     2101 cagacagtat attgttcact ttcttttaac catataagaa cacacacacc aacattatgg
     2161 tattctgtta caactcctcc cggatggagg aaaatttatc caattctgaa cctttgcggg
     2221 cccgtccgca aagaaaaata acaaccactc cctgagcgtt tcagatagag aaatgtgaaa
     2281 gagaagtgac aatgtcgaaa caaggagcaa accatgcagg tcagcagaag gcagttcttt
     2341 aagatctgcg ctggcggtat ggcaggcacc acggcggcgg cactgggctt cgcgcccggc
     2401 gtagcgctag cggaaacacg gcaatataaa ctgctgcgca cccgcgaaac ccgtaacacc
     2461 tgcacctact gttccgttgg ctgcgggctg ttgatgtaca gcctcggcga cggtgcgaaa
     2521 aacgccaaag catctatttt ccatatcgaa ggggacccgg atcatccggt aagccgtggc
     2581 gcgctgtgcc cgaaaggggc cggtctggtg gactttatcc actctgaaag ccgcctgaaa
     2641 ttcccgcaat accgcgcgcc gggttcagat aagtggcaac agatcagttg ggaagaagcg
     2701 tttgaccgca tcgctaaact gatgaaggaa gatcgcgacg ccaactatca ggcgcagaac
     2761 gccgaaggcg ttaccgttaa ccgctggctc accaccggga tgctgtgcgc ttccgcatcc
     2821 agtaacgaga cgggttattt aacgcaaaaa ttctcccgcg cgctgggtat gctcgcggtc
     2881 gacaaccagg cgcgtgtctg acacggacca acggtagcaa gtcttgctcc aacatttggt
     2941 cgcggtgcga tgaccaacca ctgggtcgac atcaagaacg ccaacctcgt cgtggtgatg
     3001 ggcggtaacg ccgcagaagc tcacccggtc gggttccgct gggcgatgga agccaaaatt
     3061 cacaacggcg cgaagctgat tgtgatcgat ccgcgcttca cgcgtaccgc gtcggtggcc
     3121 gatttttatg cgccaatacg ctctggtact gacattgcct tcttgtcagg cgtgatgctg
     3181 tatctgctga ccaacgaaaa atacaaccgt gaatacaccg aggcctatac caatgccagc
     3241 ctgatcgtgc gtgaagattt tggcttcgat gatggtctgt tcaccggcta tgacgcagac
     3301 aagcggcagt acgataaaac cagttggcac tatgagctgg acgaaaacgg ttttgccaaa
     3361 cgcgatacga cactgcaaca cccgcgctgt gtctggaatc tgttgaaaca gcatgtctca
     3421 cgctatacgc cggacgtggt agaaaatatc tgcggtacgc cgaaagcgga cttcctgaaa
     3481 gtgtgcgagt acattgcaga aaccagcgca aaagataaaa ccgcgtcgtt cctgtacgcg
     3541 ctgggctgga cgcagcattc catcggcgcg cagaacatcc gtactatggc gatgatccag
     3601 cttctgctcg gtaacatggg gatggcgggc ggcggcgtta acgccctgcg cggtcactcc
     3661 aacattcagg gactgaccga cttaggactg ctgtcgcaaa gtctgccggg ctatctgacg
     3721 ctgccgagcg aaaaacagac cgacctgcaa acctatctgg ctgccaatac gccgaagcca
     3781 ttgttgaagg atcaggtcaa ctactggggc aactatccga aattcttcgt ctcgatgatg
     3841 aaggccttct ttggtgataa agcgacagcg gaaaatagct ggggcttcga ctggctaccg
     3901 aagtgggaca aagggtacga tgtactgcag tacttcgaga tgatgaaaca gggcaaggtc
     3961 aacggctata tctgccaggg ctttaacccg gtggcttcat tcccgaacaa aaacaaagtg
     4021 gtcgcgtcgc tttccaaact gaagtaccta gtgactatcg atccgctcaa cacggagacc
     4081 tccaccttct ggcaaaacca cggtgagtcg aacgatgttg atccgtcaaa aatccagacc
     4141 gaagtgttcc gtctgccttc cacctgtttt gccgaagaga atggttcgat cgtcaactcg
     4201 ggtcgctggc tgcagtggca ctggaagggc gcggacgccc cgggaattgc catgaccgac
     4261 ggcgaaatcc tcgccggtat cttcttacgc ctgcgtaaga tgtactctga acagggcggc
     4321 gccaacccgg aacaggtgtt gaatatgacc tggaactaca ccaaaccgta cgaacccgcc
     4381 tctgaagaag tggcgatgga aagtaatggt aaagcgctgg ccgatcttat cgacccggca
     4441 accggcgcgg tggtagtgaa gaaaggtcaa cagctcagtt cgttcgcgca actgcgtgat
     4501 gacggtacga cgtccagcgg ctgctggatt ttcgccggta gctggacgcc ggaaggcaac
     4561 atgatggcgc gtcgtgataa cgccgacccg tctggtctcg gcaacacgct gggctgggca
     4621 tgggcatggc cgcttaaccg ccgtattctg tataaccgcg cttccgccga tccgcagggt
     4681 aacccctggg acccgaaacg tcagctactg aaatgggaag gcggaaaatg ggccggatgg
     4741 gatattccgg actacagtgc cgctgcgcca ggcagcgacg tcggaccgtt tatcatgcag
     4801 ccggaaggga tgggtcgcct gtttgctatc gataagatgg cggaagggcc gttcccggaa
     4861 cactacgagc cgtttgaaac gccgctgggc actaacccgc tgcacccgaa cgttatctct
     4921 aaccctgccg cccgtatctt taaagacgat gccgacgcgc tgggtaaagc ggataagttc
     4981 ccgtatgtcg gaaccactta ccgtctgacc gagcacttcc actactggac caagcacgcg
     5041 ttgcttaacg ctatcgccca gccggaacag tttgtggaaa ttggcgagaa gctggcgaat
     5101 aagctcggta tcgcgcatgg cgataccgtg aaggtctcct cgaaccgcgg ctatatcaaa
     5161 gccaaagcgg tggtgaccaa gcgtattcgc acgctgaaag cggacggcaa ggatatcgat
     5221 accatcggta ttcctattca ctggggctac gaaggcgtgg cgaaaaaagg ttttatagcc
     5281 aatacgttaa cgcctttcgt cggcgatgcg aacacgcaaa cgccggagtt taaatccttc
     5341 cttgtgaacg tggaaaaggt gtaacggaga cgacctatgg cttatcaatc gcaagacatc
     5401 attcgtcgtt ccgccactaa cggtttcacc cccgcgcccc aggcgcggga ccaccaggaa
     5461 gaggtggcga aactcatcga cgtcaccacc tgtatcggct gtaaagcgtg tcaggtggcg
     5521 tgctccgagt ggaacgacat ccgtgatgaa gtgggcaata acgtcggggt gtatgacaac
     5581 ccggcggact taactgcgaa atcctggacg gtgatgcgct tctcggaagt ggaacagaac
     5641 gacaaactgg agtggctgat ccgtaaggat ggctgtatgc actgcgccga tcccggctgc
     5701 ctgaaggcct gtccggcgga aggggcgatc attcagtacg ctaacggtat tgtcgacttc
     5761 cagtccgagc agtgtatcgg ctgcggctac tgtatcgctg gctgcccgtt caacgtgccg
     5821 cgcctcaacc cggaagacaa ccgcgtctat aaatgtacgc tgtgcgttga ctgtgtggtg
     5881 gtcggccagg aaccggcctg cgtgaagacc tgtccaaccg gcgctattca ttttggctcg
     5941 aaagaggata tgaaaacgct ggcgggcgag cgggtggcgg aactcaaaac ccgtggttat
     6001 gacaatgcgg gtctgtacga tccggcgggc gtaggcggta cgcatgtcat gtacgtgctg
     6061 catcatgccg acaagccgaa tctgtatcac ggtctgccgg agaacccgga aatcagcgaa
     6121 accgttaagt tctggaaagg cgtctggaaa ccgctcgccg cgttcggttt tgccgcgacc
     6181 tttgccgcca gcgtcttcca ctatgtcggc gtcggcccga accgcgcgga agaggaagat
     6241 gacaacctgc atgaagagaa agacgaggtg cgcaaatgaa acgacgtgac accatcgtgc
     6301 gctatacggc gccggaacgc atcaaccact ggatcgtcgc cttctgcttc gtgctggcgg
     6361 cggtgagtgg gctgggcttt ttattcccat ccttcaactg gttgatgcat atcctgggca
     6421 ccccacaact ggcgcgaatt ctgcacccgt ttgtgggcgt ggttatgttt gcctcgttca
     6481 tcatcatgtt tttccgttat tggcaccaca atctaatcaa tcgggatgat atcttttggg
     6541 caaagaatat tcgtaagatc gtcgtcaacg aggaagtggg tgacaccggg cgttataact
     6601 tcggtcagaa atgcgtattc tgggcggcga ttatcttcct ggtgctgctg ctggtgagcg
     6661 gggtaattat ctggcgtccg tactttgcgc ctgctttctc aatcccggtg atccgattcg
     6721 cgttaatgtt gcattctttt gccgcagtag cgttaattgt ggttatcatg gtgcatatct
     6781 acgccgccct ttgggtgaaa ggcaccatta ccgcgatggt ggaaggctgg gtaacccggt
     6841 cgtgggcgaa gaaacatcac ccacgctggt accgagaagt ccgcaagaca acggaaaaag
     6901 aaactgaatg agtattcgca taatcccgca agatgagctg gggtcgagcg agaaacgtac
     6961 ggcggatatg attccgccgt tattgttccc ccgactcaaa aacgtctaca accgccgcgc
     7021 cgaacgtctg cgcgagctgg ctgaaaataa cccgctgggc gattacctgc gctttgccgc
     7081 gcttatcgcg cacgcgcagg aagtggtgct gtacgaccat ccgctggaga tggatctgac
     7141 cgcacgcatt aaagaagcga acgaccaggg caagccgccg ctggatatcc acgtgctgcc
     7201 gcgtgataag cactggcaaa aactgctgca ttcgttaatt gccgagctaa aacccgagat
     7261 gaacggcccc gcgctggcgg tgattgagaa cctggagaaa gcctcagagc aggagctaga
     7321 gcagatggcc agcgcgctgt ttgcctcgga ttttgcctcc gtcagcagcg ataaagcccc
     7381 gtttatctgg gccgcgctct ccctttactg ggcgcaaatg gccagcttga ttccaggcaa
     7441 agcccgcgcg gaatacggtg aagcgcgcca gtattgcccg gtatgcggtt cgatgccggt
     7501 ctccagcatg gtgcaaatcg gcaccacgca ggggctgcgt tatctgcact gtaacctgtg
     7561 cgaaaccgaa tggcacgtcg tgcgcgtaaa atgcagtaac tgcgaacaga gccgcgactt
     7621 acactactgg tcgctggaaa atgagcaggc tgcggtgaaa gccgaaagct gcggcgattg
     7681 cgggacttac ctgaagattc tctatcagga aaaagacccg aaagtggaag cagtggccga
     7741 cgacctcgcc tcgctggtgc tggacgcgcg catggaacag gagggcttcg cccgaagctc
     7801 tatcaacccg ttcctgttcc cgggggaagg ggaataagtt ttttactcag accgggcgaa
     7861 gtttgccgtc cggtctacaa gtgatacggc gtgatcactc ccggaatatc ggcaaagtct
     7921 tttgtattgc gcgtcacaag ctcacaacga tggacttgtg cagtggccag aatgatcgca
     7981 tccgggagtt tcatgccata ctcctgcctg acaatgacgc ttcgttccgc gatttcctgt
     8041 gttacgccaa taatattgaa cgcacttaat gcaatgcgcg tgcggttttc ctgatgatat
     8101 ttcttagcac ccaccatcac ttccatccat gtgataaggc taatcgcatt ttgtggcgga
     8161 tacgcttcca gcgcatgttt cgcttcaatt cgaccgctaa acaggtcgat gaggatattg
     8221 gtatcaaaaa gcgcagaccc tttgaccatt accattcctc acgaagttta cgttggtatt
     8281 caacgccatc ttcctcacag ccttgccaga gccccaatgc tttcgaaatt gtggtctcag
     8341 cccgatcctg tctttccaga tactgctcaa cggcctcccg caagagttct gcacgaggta
     8401 ggttgcgttg caccttgaga tcgtcaagcc gtttaatcac atcgtctgat aaatcgagta
     8461 aaattctgcc catatccatc ccagccatca tactcacata tacctccagt atatcattcg
     8521 cgcttatttt tcaaacaaca tacacctgag actgacgaga aaatagttat tacgcgaacg
     8581 atttttattt ttgcgagccg ctttccagaa tcgtacgcag cccaattttc ccattttcat
     8641 tcgaaccaaa tcgagttata aaactgtata tccatacaga taaaggcaat gaaaaatggc
     8701 actggaaagc gggattgcgc agttagtgga ggaatttatc gcggcgggac gcccctcttc
     8761 tcgcgaacag aatattgatg accggagggc gggctacatc gctagcacga cattggcagg
     8821 agaaacagaa acccgcgtcc aggttgaaga tattgaactc gatgccatga cgtttcgcgt
     8881 ggtttcgccg ctcaatgcca cagggaaatt accctgcatc atttattatc atggtggctg
     8941 ctttgtcagc ggcggttttg ccactcacga taaccagtta aggcagttag ctttttacag
     9001 ccgttgtcgc gtgattgcgg cacagtaccg acttgcacca gagcacacct tcccggccgc
     9061 acataacgat gccgaaaccg gagccaatac tatctggaaa tatgcccaga aactggggat
     9121 agatcgcgag aacattacgc ttgctggtga cagcgcgggt gggcatctgg cgctggtcac
     9181 cgcgctacgc ctgaaagccg cccgtcaatg gcaacctgca cagctgattc tgatctaccc
     9241 catgctggac gcaaccgcca ggtttgcgag ctacacctgt aatgggctgg attacattat
     9301 cacgcgtgac acgctgcttt caggctacga gatgtatatg ccgcgaaccg atccactgca
     9361 tcctgaagcc agtccgctct ggcgtgagga cttcgccggt ctgccatcca cgcacatcat
     9421 tactgccgaa ttcgacccac tgcgcgatga gggcgaggcc ctgtatcaac ggttccagga
     9481 acagggtgtg gaatgcactt gccagcgcta tctcggcgtt atccacgggt ttttccaatt
     9541 gggcggagtg agcaagacgg cgcgggacgc aatacgcgac gtggcctggc gtgttgtaag
     9601 tccatcaaca agcaaaatga cctaaaattc aattttgttt tcaacttgaa aactggataa
     9661 cgttgcgcta aattgttttc aggttgaaaa ctttgtaatg gaactacatt gtgcatgtta
     9721 tcagccgaaa actgttcaat gaagcgatgc tcatgtatcc aaaccatgag cttgctctca
     9781 ctgagttgct gaatgttctg gagaaaaaaa cattcactca gcctgaagag atgaagcggt
     9841 atattccttc gctggataat tttaagtaca gagataaatg gtgggtgatt gatgtttctg
     9901 gtaacagcct gagactcatt tcctacatag atttcaggtt acataagata tttgtgaaac
     9961 atatcgtttc ccatgccgaa tatgacaaac tgaccgcata ttatcggggt aatgaagaat
    10021 gagaactcat cgtcagatgg atgcaaccag cgcaaaaaag atcgttgata ccttcagcga
    10081 tgcggtaaaa agcgtcccac tgatggggga agaccgaaat gacaatgagt atcgcagggc
    10141 actagcgcta gtggagtttc tggtcgacca cgacgatctt gaaaacccac tatttgaatt
    10201 gctctgtgcc cgaatcagtg aatacgaaaa acatgcgccg gaattcaaag cactcaacca
    10261 acacctggag aaaacgcccc ctggcgtttc agtattgcga acgctcatgg atcaatacgg
    10321 tctcaaagca gcagatcttg ccaacgaact tggttctaaa tcgaacgtca gcaacatctt
    10381 aaatggccgc agagcactaa cggttaatca tattaaagcg cttacacaac gctttaaact
    10441 accagcggat gccttcatcg agtagttgga tatgtccagc tactcttcct cattcccgcc
    10501 ctcttcatac gggccgaacg gtttcgcagg tagtacgata taaatgcctt cgaaaattgc
    10561 cccggcggtc tcgccgccca acagttcaac ctgcaactgg acacgcgctt ttttaccccg
    10621 cgccagcctg tccaaatcac cgcttagcga ccccaaatca gccacggcgt ttggctttcc
    10681 gctaatgggt ttactgtagc gaatatgggc gtcagcaaga ataatcgtcc cgcccaggtg
    10741 gcgttcacgg agcatcagcc agataagtcc ccatccggtc agcgtcgcca gggagaacag
    10801 gctgccggca aacaccgtgt gatgcggatt ttgattaccg gtttccggca tcgtggtgat
    10861 aaatttttgc ccggtgtact gctgaatgcg cacccccatc ttttcactca atggaatgtg
    10921 ctcataccag gcctgctgaa gctgcccgca ccaatcgccg cgatgcagga tatcatccag
    10981 cgatgctacc ggtttaatca tcagaaaatg gcggattggc gtggttgtgg gcgtagtaat
    11041 ctccccctga ttgacaaacc cgagtttggc aaagaactca accgcatctt cgcgcgcgct
    11101 gcaggtgacg cgcttaacgc cttcctggcg ggcgacagac tccagggtca tcgccattaa
    11161 tgtccccagc cctttatcct gtaccgaggg atgtacagcc ataaaacgga tagacgcctc
    11221 gttatctgca ttgatataca ggcggcccac tgcaactaag tttccttctt cgtccaccac
    11281 catttgatgg tgcgccaacg catcccagcc atcccgttcc gaccctttcg gctggtgcag
    11341 cggtttacgc agcatctccc agcgaaactg gtagtaacgt tctaattctt cttctgtttg
    11401 cggaactcga aggtgataca tagccgtact ctctcttgtt atccgcggcc acgccggaag
    11461 ctgactcata cctggagcca gaatgtcacg ggaccgtcat taaccagctc aacctgcata
    11521 tcggcagcga agcgtccggt ttgcgtgttt atcgcctgct ggcggcagcg ttcgacaaaa
    11581 tattcataaa gcgcctgcgc gcgatccggc gcagccccgc cggaaaagct tggccgcata
    11641 ccgcgttcgg tatctgccgc cagcgtaaac tgcgacacca ccagcacgct gccgccagcc
    11701 tgttgtacat tcagattcat cttgccgtca acatcgctga agatacggta tcccagcacg
    11761 cgctcgcaca gacgattcgc tttttgttcg tcatcttctt tttcgacacc caataacacc
    11821 aaaagtcctg ggccgatttt acccgtcacc tcgtcctcca cggtgacgct ggcacgggtt
    11881 acgcgttgaa ttaatgcaat catggttggt cagcttcttc ttgttctgcg gcttgtttga
    11941 gttttcggta ttccccgaga gtgacagtta tttctgcgcc aagcaagact atacaccagg
    12001 tccagtatac ccagacaaac aggataggga tcactgccag tacgccataa atgagctgat
    12061 atgacgggaa catggtgata taaagcgcga aacctttctt tccggcctcg aacagcaacg
    12121 ctgcgacaaa cgcgccgaca agggcgtcac ggttcggtac gcgagttgtt gggacaatac
    12181 tgtaaagtaa ccagaatgag atccacgaga gcagcagcgg aaggatgcgc aatacattgt
    12241 cgatgaccgt attcagatcg ctggcccagc gtaaagaaag cagataggag ctgatcgcca
    12301 gactggcacc ggcgagaagc gggccgagcg tgaggatcat ccagtacacc gcaaaagagt
    12361 acacttttgg gcgtgtgcgt ttgctgcgcc agatagtgtt taaggcgcta tcaatggcgt
    12421 acatcaacag caatgccgtc acaatcagtc cacaggcgcc caccgccgtc attttgttgg
    12481 agttagcgac aaactgctca atatagcgct gaatcacgtc tccggtggct ggcataaagt
    12541 tagcaaaaat aaaatggcgt aactgaatgc tgacatcaga aaacatcgga aaagcagcga
    12601 aaagggcaaa aacgacggca ataagcggta ctaaggagag taatgagaca taggcgaggt
    12661 ttcccgccag agtcgtcata ttatcctcat cgatacgctg ccataatagc ttgagccagg
    12721 cccgaacagg gcgcgtatgg cgtccagctt tttggtgaac ggtttttagc ataacagctt
    12781 cgcgaaatag tcagggatgg tggctttatc cttcaccaga atgctggtga tccccaactg
    12841 gttggcccct tctatattat cggcattgtc gtcgaaaaag accgcatcgg cagcggaaaa
    12901 accttctttc tgcaggacgt gctgataaat acgcgcttcc ggtttacgca ttcccaaatc
    12961 ctgcgataaa tagatatggt cggcggcagc gcgcacctcc gggtattcct ccggccagaa
    13021 gtgggtatgc agtcggttag tattggataa caccaccacg cgatgcccct gctcgcgcag
    13081 tttatgcatg atagcaatca cttcgggccg taatccgaca aataccgcct gccagccgtg
    13141 cgcaaattgt tcataactga gcgataacgc catttcatga cagaaagctt cagcaaacgc
    13201 ttcgtccgtt atctcaccgc gttcatgttg gtgaaaagtc tcgcccatcg taaatttttg
    13261 cttcagcgaa gccaacggta ctcgactcag gtcgctccac acacctaata cgcggttaaa
    13321 gtcgatatcg acaatcacat tacctaaatc aaagatgtag agcatgtcat tctccttgct
    13381 aaccggggat gaataactgt agcgggaaag gagaagtttg actatgtatc cctttataaa
    13441 tcaattaaca aaaagacaat agaaacgcag acgatgccca atatcgcctg catcacagcg
    13501 ccgttttatt ggccggataa agcgctgacg cgaccctccg gcgcaagggc gcttgtcacg
    13561 ctgaaacggc gtcgtccagc gaaggactca cctgaaccac ttcgatttgc tgggattgaa
    13621 gtaaattctg taatgccgga ccgggatact cgtccgtaaa cagagcggta atctgtgaca
    13681 cattgccgat ctcaaccgcc gcagaagcat ggtatttcgt atgatcggcg gccagcagaa
    13741 tatgtcgcga gtgagccatc atggttttca ctacgctggc ttcgttgaca tcaaactcca
    13801 gtaacgcgcc atcgctctct atcgcgccta cgctggtgac gagatagtcc gcccggaacc
    13861 ccgccacaaa cgccgccgcg gatggcccga taatgccgct attatgcggg cgcagcgtgc
    13921 cgccaggcac catcacttca aagcgagggt tattataaag aatgtgcgcg acgcgcaggc
    13981 tattggtgat aatgcgcaga tgattatggt tgagcagcgc gcgcgccacc tgctcaaccg
    14041 tcgttccaat cgtgataaat atcgtggagc catccggaat atagtcagcc acggcttccg
    14101 caatggcttt tttctcttgc gtccaggaga tctctcgctg ctcaaaggcg gtattgacca
    14161 cactggacgc tctgccagcg ccgccgtgat gacgcgtaat cagcccctgc tcgcttaatt
    14221 tacgaatatc gcggcgaacc gtctgggtag agacctccaa caaactggct aactcatcga
    14281 tattcatata gccgcgctca tcaataagca ttaacagccg atcgtgtcgc ggattaccgg
    14341 tcagttcggt aagactcatg agcattcctc taaaagcttc ctactgctca tattatacaa
    14401 aaagtgacaa gaaagatcgg gtttgctcac aatcagggat acccgcccgg ccacccgggc
    14461 gcgtacactt cagcgcggca acgccgctgg cgaatctgac agcctcttcg atagcgtatc
    14521 cgcttgccag gccaaatgcc agtgcgccat gaaaaacatc gcccgcgccg gtagtatcca
    14581 ccacctccac ggtaaaaccc ggttggtggc gtaccgccgc tttttccaac cagttgcagc
    14641 cttcgctgcc tcgcgtgaca tagacatgtc catttgtgag catttgtgct ttttttagcg
    14701 catcaatggc ttcgctcatc cccgtcaggc gtgccagccc cggctcggag aaggcggcgt
    14761 ggtcgcttaa cgccaccagc tcgctaatat cctgcggcgt aatatcgcca tcaagaacag
    14821 tcatgacgcc agcctgacgc gccagcgtaa acgcctgttt tgcgccgtca tgccagcgca
    14881 catccgccaa caccacatcc cactgcgaaa aatcgatgtc gttaagccag tcggcgtcag
    14941 gtaataaatc cgggctggga taattaacga taatccgctc tcctttggca tccaccataa
    15001 tcgctgactg cgacgacatg gcctgcgtgt agcggcgggt atagcgggta tttaccccca
    15061 gggattccag ttccgccagc aggctgtttc cggtgtcgtc atcgcccaca cggccaataa
    15121 agtccacctg cgcgcccaat ttcgccgcag ccacggcagc ggtcgccgca ggcccgccgc
    15181 ccacttccgt atagcgcttc gccacatatt tgcccccttc tgttggtaat ccttccacgt
    15241 aatagatgcg atccatcacg gtaataccta cacaagcaat acgaaccatg gtcattcctc
    15301 aagcattttc gatgtgctca ttttaatttc acgaaatgtt taaaaagtga cggctgtcaa
    15361 ttttttgacc ataaattaca aatacgatca caaacagaca gaaaaaggct cattaatgac
    15421 aaaaaatgac accaccgtgt tcaggagaac gatatggcag ttatagcatt tatcgggttg
    15481 ggacagatgg gctcccctat ggcgagcaat ctgctaaagc agggccatca actcagcgtc
    15541 ttcgatatta atcccgacgc cgtacagcgt ctggtagaca aaggcgcgca acctgcaagc
    15601 agcccggctc agacaaccat cggcgctgaa tttgttatca ccatgctccc gaacggcgat
    15661 ctggttcgtt ccgttttgtt tggcgagcaa ggcgtttgtg aaactctttc ccgtgaagcg
    15721 ctggtcattg atatgtccac tattcatccg ttgcaaaccg ataagctgat tgccgacatg
    15781 cagagcaaag ggttcagcat gatggatgtg ccggtaggcc ggacatccga caacgcgatt
    15841 accggcacat tgttgttgct ggcaggcggt acgacggagc aagtagagcg cgctacccct
    15901 gttctgatgg cgatgggtaa tgagctggtc aacaccggcg gcccgggaat gggtattcgc
    15961 gtaaaactga tcaacaacta catgagtatt gcgctaaatg cgctctccgc cgaagccgcc
    16021 gtgctgtgtg aagcgctggg gctttccttc gacgtggctt taaaagtgat gagcggcact
    16081 gccgcaggca aagggcattt caccaccacc tggccgaata aagtgatgaa aggggatctg
    16141 tctcccgcct tcatgatcga tctggcgcac aaagatcttg gcatcgcgtt ggatgtcgcc
    16201 aatcaactgc acgtaccgat gccgctcggc gccgcctccc gtgaagttta taacctggcg
    16261 cgggccgcag gccgcggtcg ggaagactgg agcgccatcc tggaacaggt gcgcatcagc
    16321 gccgggctga ctgccaacgt aaaaaagtaa cgactgtata aaggaaaatt gaatgaacaa
    16381 ctacaccatc aaagacatta cgcgagcgtc cggcgggttt gccatgctgg ctgtcgatca
    16441 gcgcgaggcg atgcgtttaa tgtttgctgc tgctggtgcg aaaacacccg ttgccgatag
    16501 cgtgctgacg gatttcaaag tgaatgcggc gaaaattctt tccccgtatg cctctgccgt
    16561 tctgctggat cagcagttct gttatcgcca ggccgtagaa caaaacgcgg tcgctaaaag
    16621 ctgcgccatg atcgtcgcgg cggatgattt catcccaggc aacggtattc ccgttgataa
    16681 cgtggtcatt gataaaaaaa ttaatgcgca ggcggtaaaa cgggatggcg cgaaagcctt
    16741 aaaactgttg gtgctgtggc gcagcgatga agacgcgcag cagcgtctgg atatggttaa
    16801 agaattcaat gaattatgtc actccaatgg tttgctgagc attatcgaac cggttgtacg
    16861 tccgccgcgc tgcggcgaca agttcgatcg cgagcaggcg attatcgatg cggccaaaga
    16921 gctgggcgac agcggcgccg atctttacaa agttgaaatg ccgctctacg gcaaaggcgc
    16981 gcgttccgat cttcttaccg cctcacaacg cctgaatggg catatcaata tgccgtgggt
    17041 catcctctct tccggtgtgg acgaaaaact gttccctcgc gcagtcaggg tcgccatgga
    17101 agctggcgca tccgggttcc tggcgggacg cgcggtctgg tcatcagtga ttggtttacc
    17161 ggataccgag ctgatgctac gtgatgtttc cgcgcctaaa ttgcaacgtc tgggcgagat
    17221 cgtcgatgaa atgatggcaa aacgtcgtta atacgaggat gaaagaatga aatggtttaa
    17281 cacgttgagc cacaaccgct ggctggagca ggaaaccgac cgcatcttta atttcggtaa
    17341 aaacgccgcg gtgccgacag gcttcggctg gctgggaaat aaagggcaaa tcaaagaaga
    17401 gatgggcacc catctttgga tcacggcgcg tatgctgcac gtttattccg tggcggcgtc
    17461 gatgggccga ccgggcgctt atgatctggt cgatcacggc atcaaagccc tgaacggcgc
    17521 gctgcgcgat aaaaaatacg gcggctggta tgcctgcgtt aacgatcagg gcgtggtgga
    17581 tgcctctaaa cagggttatc aacacttctt cgccttgctg ggtgcggcca gcgccgtcac
    17641 gaccgggcac cctgaagcca gaaaattgct ggattacacc atagaagtga ttgagaaata
    17701 cttctggagt gaagaagagc agatgtgcct tgagtcctgg gacgaagcct ttagccagac
    17761 ggaagattac cgtggcggta acgccaatat gcacgccgtc gaagcgttcc tgattgttta
    17821 tgacgttacc catgacaaaa aatggctgga tcgcgctatc agaatcgcat cagtcattat
    17881 tcatgatgta gccagaaata atcattaccg tgttaatgaa catttcgatt cacagtggaa
    17941 ccctatccgc gactacaaca aagataatcc tgcccaccgt ttccgcgcct acggcggtac
    18001 gccaggtcac tggattgagt ggggccgtct gatgctccat ctccatgctg cgctggaggc
    18061 ccgcttcgaa acgccccccg cctggctgct ggaggatgcg aaaggtctgt tccatgccac
    18121 tatccgcgac gcctgggcgc cagatggcgc agacggtttt gtctactcag tcgactggga
    18181 cggtaaacct atcgtacgtg aacgcgtgcg ctggccgatt gtggaagcga tgggtacggc
    18241 ctacgccctc tacaccctga cgggcgatag ccagtatgaa gagtggtatc agaaatggtg
    18301 ggactactgc attaagtacc tgatggacta tgaaaatggt tcctggtggc aagagctgga
    18361 cgccgataac aaagtgacca ccaaagtgtg ggacggcaag taagatattt accatctgct
    18421 gcactgcctg gtcattcctc gtctgccact ggcgccgggc ctggctccgg cggtcgcggc
    18481 gggtctcctg gatatcaacg cgaaataggt catgaggatg gcagccatgc acagcggtgg
    18541 aaaaactatt cagcttaatg cgggccatta ccaggcgaaa atcgtcacgg ttggcgcagg
    18601 tctggcggaa ctgactcatc atggacgtca tgtggtcatc ccgcataaac cggaagaaat
    18661 acccatggcg catctgggga aggtattgat tccctggcca aatcgcgtga caaatggctg
    18721 ctactcctat aacggcaaag ttttccagct tgccgttaac gacccggttt cgcagaccgc
    18781 cattcacggt ctgttagcct ggcgagactg gcagattaat tatcagtcgg cgacggaagc
    18841 gtcgctaacg atttttctgc cgccctctta cggctatccc tttgcgttga tatcggaagt
    18901 gatttatcgg ttagatgccg ccagtgggct gcacgtattg attcgtacgc aaaacattgg
    18961 cgatgaatca gccccttatg gcgcgggcgc acatccttat ttgacttgta atctgcaaag
    19021 catcgatagc tgtgtattaa cactgcctgc aagcgaagaa ttgcccgcag gcaggaattt
    19081 ttccgcatca tgcctgctcg gcgaaacgcg ccttgatcat gcggttaaga ccgcgactgc
    19141 cccggcggag tgggaggtca gacttaccag cccaacgcag aacatgtcta catttttacg
    19201 cagcaagcaa ccctggctac agatctatac cggcgaaaaa ctcagccgaa aggtctcgcg
    19261 gtagagccta tgagctgccc gcccgatgca tttaattccg ggatcgcact gattcatctt
    19321 gccccaaaag cgatccatca actgcatttt tccatcggct gcgactagcc caaatggatt
    19381 accgaattac cctacattca cggagattac aatgaattct ctaccacaac ggtcaaccga
    19441 ttttgaactg acaacatcac aggatggttt tgcgcttagc tggcaacagc gcctgatttt
    19501 acgccacagc gccgaaaacc cctgtctgtg gattggcgcg ggcgttgccg acattgacat
    19561 gtttcgcggc aacttcagca tcaaagacaa acttaacgag aagattgcat taacggaggc
    19621 caccgtcagc gagctacccg acggctggct ggtacaattc agccgtggcg caacaattag
    19681 cgccaccctt cgcatctccg ccgatgaggc gggacgcctg acgttggatc tgcaaaacga
    19741 cgacctgcac cataaccgta tctggttacg cctcgcagct aatccagacg accatatcta
    19801 cggctgcggc gaacagttct cttatttcga tttgcgcggc aagccgttcc cgctgtggac
    19861 cagcgaacag ggcgttggcc gtaataaaac cagctatgtc acctggcagg cagactgtaa
    19921 agagaacgcc ggcggcgact attactggac cttcttcccg caaccgacct ttgtcagcac
    19981 gcagaagtat tactgccacg tcgataatag ctgctatatg aatttcgact tcagcgcgcc
    20041 ggagtatcac gaactggcgc tgtgggaaga taaaactacg ctgcgttttg agtgtgccga
    20101 cacctacatc gccctgctgg aaaaactgac tgcgctgtta ggtcgccagc cggagctgcc
    20161 ggactgggtt tacgacggcg tcacgctcgg cattcagggc ggtacggaag tttgtcagca
    20221 aaaactggat accatgcgca acgcaggcgt aaaagtgaac ggtatttggg cgcaggactg
    20281 gtccggtatc cgcatgacct cctttggcaa gcgcgtgatg tggaactgga agtggaatag
    20341 cgacaactat ccacagctgg atagccggat caaacagtgg aaagaagaag gcgtccagtt
    20401 cctctcttat atcaacccat acgtcgccag tgataaagac ctctgcgctg aggcggcgag
    20461 acacggctat ctggcgaaag acgccacggg cggcgactat ctggtcgagt ttggcgaatt
    20521 ctatggcggc gtggtcgatc tgactaatcc tgaagcttac gactggttca aagatgtcat
    20581 caaaaagaac atgatcgcgc tcggctgcag cggctggatg gcggatttcg gcgaatatct
    20641 gccgaccgac acgtatctgc acaacggcgt cagcgcagag atcatgcata acgcctggcc
    20701 cgcactgtgg gcgaagtgta actacgaagc gctacaggag accggcaagc tcggcgagat
    20761 cctgttcttt atgcgtgcgg gttacaccgg cagtcagaaa tattccacca tgatgtgggc
    20821 aggcgaccag aacgttgact ggagtcttga tgatggtctg gcctctgtcg tgcctgctgc
    20881 attgtcgctg gcgatgaccg gccatggtct gcatcacagc gatatcggcg gctacaccac
    20941 cctgtttgac atgaagcgca gcaaagagtt gctgctgcgc tggtgcgatt tcagcgcctt
    21001 tacgccgatg atgcgcaccc atgaaggcaa ccgccccggc aataactggc agttcgacgg
    21061 cgacgcggaa actattgccc actttgcccg catgaccacc gtctttacca cgctgaaacc
    21121 gtatctcaag caggcggtgg cgcaaaacgc ggctaccggt ctgccggtca tgcgtccgct
    21181 attcctgcac tacgagaacg atgccgctac ctacaccctg aaatatcaat atctgctcgg
    21241 tcaggatctg ctggtcgcgc cggttcacga gcaggggcgt tgcgattgga cgctgtacct
    21301 gccggaagat cactgggtga atatctggac cggcgaagct caccacggcg gtgaaattac
    21361 cgtggatgcg ccgattggca agccgccggt cttctatcgc gcgaagagcg agtgggcttt
    21421 actttttgct tctttacgga atatctaata cggctcgccc gcagggaaac ctgcgggcag
    21481 atggagaaga ataatgagtc aaacatcatc gaatccggca accatacgct tgccgtttaa
    21541 agaaaaactt gcctatggac tgggggattt aggttccaat atcctgttag atatcgggac
    21601 cctctattta ctcaaatttt ataccgatgt gctgggttta ccagggactt acggcgggat
    21661 cattttcctg atcgccaaat tttttaccgc atttaccgat atgggtaccg gcattatgct
    21721 cgactcgcgg cgtaaaattg gtccgaaggg caaattccgc ccgttcgtgc tttacgcggc
    21781 atttccggta acgctactgg cgattgctaa ctttgtcggc acaccgtttg aggtgacggg
    21841 aaaaaccgtc gtcgcaacga tgctgtttat gctgtatggg ctggttttca gcatgatgaa
    21901 ctgctcgtat ggcgcgatgg tgcccgcgat taccaagaac ccggatgaac gcgcctcgct
    21961 tgccgcgtgg cgtcagggcg gcgccactct cggcctgctg ctgtgtaccg ttggctttgt
    22021 gccggtcatg aacctgatcg aaggcaatgc ccaactcagc tatattttcg ccgccacgct
    22081 attttcattg tttggcctgc tatttatgtg gctgtgctac gccggcgtta aagagcgcta
    22141 cgttgaagtg aaacctgtcg atagcgcgca aaagcctgga ttattgcagt cgttccgcgc
    22201 catcgccggt aaccgcccgc tgtttattct gtgtatcgcc aacctttgta ctctcggcgc
    22261 cttcaacgtc aaactggcga ttcaagttta ttacacacag tacgttctta acgacccgat
    22321 cctcctctcc tggatgggct tctttagcat gggctgtatt tttatcggcg tctttttgat
    22381 gcccggcgca gtcaggcgtt ttggcaagaa gaaagtctat atcggcgggc tgttaatatg
    22441 ggtggcgggc gatctgctca actacttctt tggcggcggc tcggtcagtt ttgtcgcctt
    22501 ctcctgcctg gcgttcttcg gttccgcctt cgtcaacagc ctgaactggg cgctggtttc
    22561 cgacacggtg gagtacggtg aatggcgcac cggcgtccgc tcggaaggga cggtttacac
    22621 cggcttcacg ttcttccgta aggtctccca ggcgctggca gggttcttcc ccggctggat
    22681 gctgacgcaa atcggttata tcccgaatgt ggtgcaatcg gcaggcaccg tcgaaggcct
    22741 acgccagttg atctttatat atccttgcgt gctggcggtc atcaccatta ttgcgatggg
    22801 ctgtttctac aacctcaacg agaagatgta cgtgcgaatt gtggaagaga ttgaggcccg
    22861 gaaacatacg gtttaacaac aataaaatat aacgccctgc ggggcgtttt gagaggcgat
    22921 tatgtctaat catgatccgc taacgctaaa gttgagcctg cgggaaaaat gcgcctatgg
    22981 cgtgggcgat ttcggctcaa atctgatgct gtgtatcggt acgctgtatc tactgaagtt
    23041 ttataccgat gaactcggga tgcctgcata ttacggtgga attatctttc tggtggcgaa
    23101 attcttcact gcttttaccg atatgctcac cggcgtattg ctggattcac gccgtaatat
    23161 tggcgcaaaa ggaaagtttc ggccttttat tctgtatgcg tcatttccgg tggctctggt
    23221 tgctactgcg caattctttg ccactcactt tactttaccc gttaaaacag ccttcgcgac
    23281 ggtgctgttt atgttgttcg gtctgttcta cagcctgatg aactgctcat acggcgcgat
    23341 ggtacccgct attaccaaaa atccgcatga gcgggcccag ctcgccgcat ggcgacaagg
    23401 cggcgctacc attggccttc ttctttgtac cgtaggtttt atgcccattc aggcgctgtt
    23461 tacccgttcc ccttcgctgg gttatctggt tgcagcagtc attttttcgg tctgcgggct
    23521 gttcagcatg tggtggtgct ttagcggggt gaaagaacgg tatatcgaaa ccgtacctga
    23581 cacgcataaa cccagcatat tgaagtcctt ctgcgcgatt tttcgtaatc cgccgctgct
    23641 ggtgctctgc gttgccaatt tgtgcacgct ggctgccttt aatattaagc tggccattca
    23701 ggtttattac actcagtacg tgctgaacga tattcatttg ttgtcatgga tgggtttttt
    23761 cagcatgggc tgtatcctga ttggcgtctt attagtacct gatgcggtaa aacgcttcgg
    23821 gaaaaaacag gtttatcttg gtggtctgat actgtgggcc gttggcgata tcctgaattt
    23881 tatctggggc ggaacgtcat tcctgtttgt tattttctct tgtattgcct tcttcggtac
    23941 cgctttcgtc aacagcctga actgggcgct ggttccggat acggttgact acggcgaatg
    24001 gaaaacgggt attcgcgctg aaggctcggt gtatacgggt tatacctttt cccgcaaaat
    24061 ttccgctgcg cttgctggct ttttgccagg tattatgctg acgcaaatcg gttatatccc
    24121 caacatagct caaagtgaca ccacgttgct tggtttgcgt cagctcattt ttttatggcc
    24181 ttgtggtctt gccattatcg cagcactaac gatgggcttt ttttataagc tcaatgaaca
    24241 acgtttcgct tttattatcg aggaaattgc ccaacgaaag aaaacaggca atcaaattgt
    24301 cgcaactaat aataaacaaa gtatttctac tgtaaataat taaacgacgc ttgccgcttt
    24361 attcatcccg atggatggcg gcttccctat atttgaaaaa tggatttatt atgaaatctc
    24421 tgaatactct agtgatatta acttcagtaa tatccacctc tgtttttgct ggcgcttatg
    24481 tagaaaaccg tgaggcctat aacctggcgt ctgaccaaat ggagtttatg ctgcgcgtcg
    24541 gctataactc cgatatgggg gccggaatta tgttgaccaa tacctatacg ctacagcgtg
    24601 atgatgaatt aaagcacggt tataatgaga ttgagggctg gtatccgtta tttaaaccta
    24661 cagataaatt aaccatccag ccaggcgggt taataaacga caaaagcatt ggttccggcg
    24721 gcgccgtcta tctggatatt aactataaat ttaccccgtg gtttaatctt acggtacgta
    24781 accgatataa tcacaataat tatagttcaa ccgatttgaa tggcgaactg gataataatg
    24841 acagctatga aatcggtaac tattggaatt ttatcattac cgataaattt tcttatacct
    24901 ttgaaccaca ctatttttat aacgttaatg attttaatag tagtaatggt acgaagcatc
    24961 attgggaaat cactaatacc ttccgttatc gtatcaatga acactggttg ccctactttg
    25021 aattacgctg gttagatcgt aacgtgggcc tctaccatag agagcaaaac cagattcgta
    25081 tcggggcgaa gtatttcttc tgatattatc gcctctattt tccgaatctg catcacagcg
    25141 ggtagttgtt ctgcccgctc attcatcctg aatcagactc ccgatatccc gcctctaagc
    25201 gccatgataa tattcgcaaa gcgttttacc atattcatgc ttatagagaa gggaaacaaa
    25261 tgaataagcg attcaatatt gattgggaca atgaattaac ccaggaacag ctcattaatt
    25321 taattttaac cgatgaagat ctgccaaagc ttcgctcact gaccattggt aactggggtg
    25381 attgttggga agacgaaacc tgccagccta ttattgatat gattgtggag aacgcccccc
    25441 gtttttctca cctggaatca ctgtttatcg gtgatatgga gagcgaagac tgcgagatct
    25501 cctggattaa acaaggtgac tattccaggc tctatgcggc gttacccaat ctgaaggaac
    25561 tgattattaa aggcgcgtcg gatctgcgac tgggcgctat acatcatgag aaactggagc
    25621 acctggaaat catttccggc ggcatccctt ctaacgtact tgccgaacta caaaatgcgc
    25681 agctccctgc attaaaaacg ctgaagctct tcctgggcgt agaggaatac ggttttgacg
    25741 gttcgctgga taacgtgatg gcgctggtat cgaaagatct tttccctcag ctcaaccatc
    25801 tggggttgat gaacagtgaa gagcaggatg atatcgcccg ccgggtgctg gaaagtaata
    25861 tcctgccgca gcttaacgtg ctggaactct catgcggtac cttaactgat agcggcgcag
    25921 aggcgctgct ggagcataaa gaccgaattg cgcatctgga aacactcgat ctccaccacc
    25981 actatttgac gccggagatg caggaaaagc taaaagccgc gctgccgata ccgctgaatc
    26041 tttcagaagc gctggagcct gatgattacg atggcgatat ttatatgaat gcgatgtaca
    26101 ccgagtgatt gtgtagggga atgtgcacat tcccctacac accgataaag ggatttattg
    26161 tgattacgct cattggcccc catcagagca agcgcacgca ttattttatg caggctgccg
    26221 ccatacttgg ggaatccgtc acggcgctga ctcatccgca agcgctggac gcttcgctga
    26281 cctctggcat cgttaaaatc gacccgccag tacacaatga aactaacatc cgcaaaataa
    26341 acgcgatcgg tctggactat atccattttt tgcagaacat ggcagcgcgt cctggcatca
    26401 cctagcttaa ccatccggcg ggcctcattc acctgttgga taaaaaacgc tgcaagcggc
    26461 gcttactgga acacggcatc cccacgccgc cgttggtagc ggaagacgta aaaagttttg
    26521 cacagctcac cgccatcatg gaggaaaaaa gggtcgccag cgtgttcatt aagccctcgc
    26581 tgggttttgg cgcggcgggc gttatcgctt tgcgccgtca tcctgacggc gcaaagcagg
    26641 tgctttacag cgcgattgcc atatcagggc aacagctatt taacagcaaa aaaatccaac
    26701 agtatcgtca gaaagaagat atccagctca ttattgatgg cgttcttcag caggaaaacc
    26761 tcgtcgaaca gtggctgccc aaagccagcg taaagcataa aacctatgat ttacgcatcg
    26821 tctgtctgga tggcgaaatt atctggcgag tggtcagaac ctcctcgcag cccattacta
    26881 acttacacct gcaaaaccag gcttaccgct tcgaaagtct ggagttatct gccgcaaaag
    26941 tggctgagat cgatacgctc tgtcaaaatg ccatgcggct ttttcctggc attcgcttag
    27001 cgggtattga tgttttactt accaccagcc tgacgccgta tattattgaa attaatggcc
    27061 agggtgattt gatttatcag gatgcgcagc agaacaatct aatttatcag gcgcaaatcc
    27121 gggccatgag gaagcaaaat gtataattca atggatgaag tccccgtctc gctacacgcg
    27181 tcgattgaca caggcgatgg cgaattcgat atgaatgcgc taattagtaa taacgctcat
    27241 attcttttta ttgtactgga ctcgttacgc tacgatattg cgcttcagga acaaaccgcc
    27301 ggaaatacgc ccaaccttaa tcattatgga caatggacga aatgcgaggc ggccggtaat
    27361 tttacctggc cttcgcatca cgccatgttt tcaggtttta tgccaaaacc tattgatgat
    27421 accgttaatc agaccatgct gcttttccca aaagatatcg gacttggtcg taaaggcccg
    27481 aaaaatgcat ttgcctttga tgacgcaaca tggataaaaa gtctggaaaa taaaggctac
    27541 cagaccatct gtattggcgg cgtctctttc tttaataacc gctccggcat gggaaaagtg
    27601 ttcccgtcga tgtttaaaga gagttactgg catccacgct ttgcctgtac ggttaaagaa
    27661 agtatggata accagatcca ttatatccag aaaatcatgg ccgaacgtgc tggcagccaa
    27721 ccggtcatga tgtatatcaa tatcgatacg attcattacc ctaaccattt ttacgttgag
    27781 ggcgcggccc ctggcgatac cgtagagacc catgccgccg cgctacgcta tatcgacgcc
    27841 cgcatcgacg gattactgaa cattttccgc caaaccggcg gcgaaacgtt cgttattgtc
    27901 tgttccgatc acggtacctg ctatggcgaa gacgggaaat atttccatag ttttaat
//
LOCUS       DAJVBX010000031        27754 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.031, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000031 DAJVBX010000000
VERSION     DAJVBX010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 27754)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27754)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27754
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.031"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..417)
                     /locus_tag="OPV72_001212"
     CDS             complement(<1..417)
                     /locus_tag="OPV72_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913571.1"
                     /translation="MEYALFVMFCLALYCPCFTLIALFTPWKGFAVFSVTYRRRQYWA
                     VHLALLDRVGAMNRRQARRYHQAFVQALETALVARPVRPVFFRSHLMRPAQVALTCQV
                     LSHRTGYRCRIAPITLPRWERVAIFAQMLLQEWRLIQ"
     gene            complement(514..1665)
                     /locus_tag="OPV72_001213"
     CDS             complement(514..1665)
                     /locus_tag="OPV72_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCR9913572.1"
                     /translation="MSRPQRIKKMSLSKALDKYYATVSVHKRGHQQEFYRVRVIQRHP
                     LAEKMMDEITTVDIASYRDDRLSQVNTRTGRCISGNTVRLELALLSSLYNLASVEWGT
                     CRTNPVEMVRKPKISGGRDRRLTSQEERRLSRYFQEQNPALHAIFHLAIETAMRQGEI
                     LSLRWEHIDLQHGVAHLPMTKNGSSRDVPLSRKARHLLQGMTVALSGNVFHYSSSGFK
                     SAWRVALQRLNIVDLHFHDLRHEAISRLFELGTLNVMEVAAISGHRSLNMLKRYTHLR
                     AYQLVSKLDARRRQTQKIAPYFVPYPACIESVNEGSDGCCGFRVHLPDFDNLSVSAAS
                     RESALEAAGVLLLRTLAKAAQRGERVPRPGDLPEGKHERVMIHPLLSAA"
     gene            complement(2013..3320)
                     /gene="pilV"
                     /locus_tag="OPV72_001214"
     CDS             complement(2013..3320)
                     /gene="pilV"
                     /locus_tag="OPV72_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shufflon system plasmid conjugative transfer
                     pilus tip adhesin PilV"
                     /protein_id="HCR9913573.1"
                     /translation="MKKQKHDGGFVAMSVGAGLLIVLVMASLAARYMGDYLKSREWQV
                     VAMQTNRFTQAVSSYVGKFYPTVLASATTTTPAVVTTQMLKNTGLLPASFSETNSYGQ
                     QYQAMIVRNQQNQELLQGMVVSRGGHAMPFTALSQISKDITAGFGGYVEDGQTAVGAM
                     RSWRIPLSSYGTSTGRGHLAVMLSTDDLSGAREDGDRLYRFQVNGRPDLNKMHTAIDM
                     GGNNLNSVGTVTASNVAGQNGNFGVSLVSNGPITAGGDIRSTGGWIVTRSGKGWMDET
                     HGGGLYMSDNDWLRILNNKGFYTGGEIRGGKIRSDGDVSAGGILTLDKINVASTACPV
                     NGAISRDTAGATLSCQSGIWSSYRLNFNIQTFNVGKNVRNQYIGVHAYCAWTYLNGSP
                     LGGFQEIHSNGSNGWYISNYRWGNYESGGTISVTCLNLPGAGL"
     gene            complement(3317..3979)
                     /locus_tag="OPV72_001215"
     CDS             complement(3317..3979)
                     /locus_tag="OPV72_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000218700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HCR9913574.1"
                     /translation="MTVSLIGTIFPPVYAIPAFIGCAIFGAVLLRPVRLYLAAAEVDI
                     SRHCAVVVGIWLFAVTGLLILMAPQVWMTRIGMLFMCSFLLQLGVMDATSGWLPRPFT
                     AACLCSGLLFCLAFHREPELRFMETAAMAVVMGSICHGVNRRRPQLGVGDVWLVCALV
                     GWMGVTDALQAAFFGLSGFMLWQWIVHRDFLRCGVLGPWLCAGCIPVIVDRLYQPEWI
                     LR"
     gene            complement(3976..4452)
                     /locus_tag="OPV72_001216"
     CDS             complement(3976..4452)
                     /locus_tag="OPV72_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000334696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HCR9913575.1"
                     /translation="MCGYFSRLALFMTLCSVPLWVQAFCFDAAAAKYHVSPLLIKSMA
                     IGESNLDPHATNDNRDKKTGKIKSTDYGLMMVNSTHIPRLVSMGVIRDKNDLLNKPCL
                     NVQIGTWILAKHFQVCGVSWNCLGSYNAGFRPDRHETRERYANRIWKIYQRQTGAQ"
     gene            complement(4462..5055)
                     /locus_tag="OPV72_001217"
     CDS             complement(4462..5055)
                     /locus_tag="OPV72_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein PilX"
                     /protein_id="HCR9913576.1"
                     /translation="MNEVSTLNPCNRPDRGMSADAGATALFILVIIGVIAAAVWSMWG
                     KKDAGTELTNYQTLATNTIGMMKGVDGYAFTSGAKMTDTLIQAGAAKGMTVSGDPASG
                     SATLWNSWGGQIVVAPDTAGGTGFNNGFTITTNKVPQSACVSISTGMSRSGGTSGIKI
                     NGNNHTDAKVTAEIASSECTADNGRTGTNTLVFNYNG"
     gene            complement(5097..6182)
                     /locus_tag="OPV72_001218"
     CDS             complement(5097..6182)
                     /locus_tag="OPV72_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000074784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HCR9913577.1"
                     /translation="MSPLYRLRRALARRFFTSGYRLRFYRMLSLQMRNGVKLLEALEQ
                     ISNMYTDFGQRTHGFGFLVDDCRAALTDNSGDNSLEHALANWVPAEEAALISAGMFSG
                     RLPEALAEAEILIDCRRRIRQAIMRMAVYPLGCIAMLGGTLGVIQTQLIPTLAGMSDP
                     QTWTGVLGSLNGLLIFFTEHGVVMGAGLALLVAWTRWSLSNWIRPDRLRRLADRHVPW
                     AVYSDIQGAIFLINMGALLCAGVRTLTALQVIHRFASPWLVVRLNAVMEEVEEGASFG
                     MALRECGYAFPSKEAVNYLSMVSGDGAAQMIARFGQEWLEETVKRVNRRGIAVMLFSM
                     VMLFALIGVVVVAVIEATSMTESMGQY"
     gene            complement(6179..7894)
                     /gene="tadA"
                     /locus_tag="OPV72_001219"
     CDS             complement(6179..7894)
                     /gene="tadA"
                     /locus_tag="OPV72_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HCR9913578.1"
                     /translation="MSEHNDAVLLYHNPDTTILELLVDSQRRTDVAVQQKVMSLMEEN
                     PGVTMRLVTRSELLRYSEMARQQSEKGEKGLRLEDIKKEVSSRQGDVLNYFMVAKDIG
                     ASDIHGTTRPGLTRIEMRVHGELETVSELAEEDGKAQAATIILSMCDVTEPQFYAGRK
                     QDGRVAAKFLRKVGLFGARYSHTPTADGLHFVMRVIPDDGDVVPTLEKLGFLPKQIRL
                     IKRTLRLPEGMIILSGPTGAGKSTTLRACSDLYLKRTRYKKRLLTVEDPPEGRIVGAI
                     QTPIICDKADEAEVRLAWQRVLTSALRLDPDAILPGELRDLISILAGIFAAQTGHLVL
                     STLHSNSAFSIPERMITMGANAGLVADAQLLVGLISQRLVQVLCPECRIPWSVKKEHL
                     TTEEREYLEKYCSVEGVCQPENLHFRNEEGCPTCRKAVIIGGKQVATVGKGVAGRSVV
                     AEVVRTDSTLFRLLLQQGKEAAKAYWIREMGGITRRIHLLHKLNDGLVDPLDADLIIP
                     LDEDEVMQVVSDQVASSSDIDTSLIERLAMVIAASVREGMKQGVEEAIKEGVAAGMAA
                     LKEVA"
     gene            complement(7904..8491)
                     /gene="pilP"
                     /locus_tag="OPV72_001220"
     CDS             complement(7904..8491)
                     /gene="pilP"
                     /locus_tag="OPV72_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000928959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus biogenesis protein PilP"
                     /protein_id="HCR9913579.1"
                     /translation="MLMPKNSVFISGVLLMAFSAGAFSQPTLAVPPSAEVISAMPASE
                     PATEAAASISSADLSDTVPIFPGNSVTAGQLEALQGKNLLLEAKVQAARLLKELTSAQ
                     TPGDVGNVPTTSPFVMGMPAEMNATPVHTPPATGRITVLEVSGRGNALQATLSFPDGR
                     QSLVQTGSVIPGTSLKVKAITLSSVTLSDGQQLTF"
     gene            complement(8472..9758)
                     /gene="pilO2"
                     /locus_tag="OPV72_001221"
     CDS             complement(8472..9758)
                     /gene="pilO2"
                     /locus_tag="OPV72_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 4b pilus protein PilO2"
                     /protein_id="HCR9913580.1"
                     /translation="MADIPLSGKPRTQVLRWQRQNWVAGLRWEEKQKSVRRAPVQRRG
                     VLNVVLTVKQGKSRLTALGQIEAGWRHQKLYSLAALFSQQCTPNGYGVYQLDDGRQVF
                     LATVKGMPSPMADVIGTPDQIIRARELFLSFNPAPEDGWTIPSSPEFPLSWNTLVGQV
                     SSAQLRFARVAGVSNPLRPYGAGVLSVAALLGGAVWWSRLPEPPVAPVVQELPAPVQD
                     VFKKTPEPVYLPHPWADMPVARHFLNRCQRWRAAVPVSLDRWRLERIRCSAEGLETVY
                     QRQPGGTAAGFAERVKQVFKRTPVFNLVSGGNEGVVFIPWAKFTLQDETAPDAGTQLM
                     QAVSWFQSRQVSFSLSEVKTPPAMPGDGAGNDAPQPIQDWHEYTFSITDKHMPEWILQ
                     GLDMQGVRLSSVGYTLSPQGQFTYQIEGHLYAYAKK"
     gene            complement(9760..11056)
                     /locus_tag="OPV72_001222"
                     /pseudo
     CDS             complement(9760..11056)
                     /locus_tag="OPV72_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001324592.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PilN family type IVB pilus formation outer
                     membrane protein"
     gene            complement(11470..11889)
                     /gene="pilM"
                     /locus_tag="OPV72_001223"
     CDS             complement(11470..11889)
                     /gene="pilM"
                     /locus_tag="OPV72_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus biogenesis protein PilM"
                     /protein_id="HCR9913581.1"
                     /translation="MGWFIVALGTVFLLVVGHVQTTQRSEVVKAQQSGSSYLLARQML
                     LLAAGINDWRYRHTLTDGTVALSELALPVAPDSRIRHVIVANRLWVWMPEVPGLVDAL
                     REQSGGSALTGTVTQGQLVWLSGIGNGPFSARVVPDD"
     gene            complement(11892..13136)
                     /locus_tag="OPV72_001224"
     CDS             complement(11892..13136)
                     /locus_tag="OPV72_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TcpQ domain-containing protein"
                     /protein_id="HCR9913582.1"
                     /translation="MNTQALFCLSLPLVIAGCAQQTSTQTARDSAFAQSQQPSVFSDI
                     YQRSPEVTRSGRYTLVSIKSADAQREPLNQLIDITMPGQLVNSVGDGFRYLLFQSGYS
                     LCGHYGADFSELLNRPLPAVQRKIGPMRLSEALQVVAGPAWRMSVDEVNREVCFVLRD
                     AYRVQAKTKALTSVTPAVTGAARTSSPETTRNPYTGVLPGNKAEPVIAGQHLAAKKGT
                     ELKPVSQSLPVPALRPGGTPVTSGVSSAPPVKQVSSPAPRNPFTGKNLTGTTLSASHS
                     PAPVGEKAQAKTPSPSTVKAVNPATATVLATTTKPLTGTPVAAVASGPEWKAVVGSTL
                     KESLTDWAGRADCPGGGHWVVIWQTPTDYRIDAPLVFKGNFETALVQVFDLYKKADKP
                     LFAEASRLQCLVSVADKPADRS"
     gene            complement(13301..14251)
                     /locus_tag="OPV72_001225"
                     /pseudo
     CDS             complement(13301..14251)
                     /locus_tag="OPV72_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368221.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
     gene            complement(14317..14853)
                     /locus_tag="OPV72_001226"
     CDS             complement(14317..14853)
                     /locus_tag="OPV72_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HCR9913583.1"
                     /translation="MASKGVNKVILVGNLGQDPEVRYMPNGGAVVNLSLATSDTWTDK
                     QTGDKKERTEWHRVVLYGKLAEIASEYLRKGSQVYIEGALRTRKWTDQSGVEKYTTEV
                     VVSQSGTMQMLGGRNSAGSGQQQGGWGQPQQPAAPSHSGMPPQQHPANEPPMDFDDDI
                     PFAPFGHSVARHALYVLS"
     gene            complement(14866..15084)
                     /locus_tag="OPV72_001227"
     CDS             complement(14866..15084)
                     /locus_tag="OPV72_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913584.1"
                     /translation="MLTSPSSSTGLLAAKFAGLSLPLQVLRSGAGYYIGTQNEEGPVS
                     RESVEYFSTQSQAEHALKQGTWSQREQA"
     gene            complement(15165..15614)
                     /locus_tag="OPV72_001228"
     CDS             complement(15165..15614)
                     /locus_tag="OPV72_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3577 domain-containing protein"
                     /protein_id="HCR9913585.1"
                     /translation="MSKETNYFNLNINGLGYITNVRQVVNGNSKFTCCTLNALSGPTD
                     NADYTRFDVTVAGKDATSLINRCQKSCDEDKKVMIGFVLSGIKSDIFTLAKGDHAGEN
                     RVSLKTRLIRVDWIKIDGAIVYKAEKPDSTPPAQSQPAQKQYAEDSF"
     gene            complement(16282..18276)
                     /gene="topB"
                     /locus_tag="OPV72_001229"
     CDS             complement(16282..18276)
                     /gene="topB"
                     /locus_tag="OPV72_001229"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001241569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HCR9913586.1"
                     /translation="MRLVLCEKPSQGRDIAKFLGATQRGEGFLNGPGVTVTWARGHLL
                     ETAEPEVYGEQYGKPWRTDVLPLLPQQWKLVVKADAKAQFAVINRLLKQVDEVVIATD
                     ADREGEVIARELLDYCKFQGRVFRLWMSALDDASIRSALADLWPSSRTESLYYAGVGR
                     SRADWLIGMNLTRLFTLLGREAGIGNVLSVGRVQTPTLAIVVKRDREIDNFVSKPYFE
                     VIATMAVNGVLFPSKWVPAAQYCDEEKRCIQSGVAAQVVQLCRQTPTAAIINCQIERK
                     KQSAPLAFSLSTLQQACSRHWGMPAQTVLDIAQKLYETHKLTTYPRTDCGYLPLSMRE
                     EIPQVLSAVVGTDPALQPVVASLDTQFVSRIWNDKKITAHHGIIPTKHTGDLSKLSDA
                     ERNVYQLVRLHYLAQFLPQMEIDVTEATFNIGGQLFRTRGNVLVKPGWKSLFGKMSED
                     DEDNTGETTLPAMQAGQVCQVQGAEQKVLQTKPPAPYNDGTLIAAMTNAAAFVTDAAL
                     KKVLKENAGIGTEATRAGIIDTLLKRGFLVREKKTLKSTPLGRNLVDVLPGTLTNPGL
                     TALWEQMLDEVAAGRVSLDDFMAKQSQWVSQLVAQGRSQPLTMQAPPSPPCPVCGGKT
                     LQRNGKSGLFWGCLKYPECKGIVNNGNKGPRGRRRKPSPA"
     gene            complement(18387..19163)
                     /locus_tag="OPV72_001230"
     CDS             complement(18387..19163)
                     /locus_tag="OPV72_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03761 family integrating conjugative element
                     protein"
                     /protein_id="HCR9913587.1"
                     /translation="MSEKEQVSVSRKAGALRSALNIALNTDYAINLWQGRPPEEEGEK
                     EGKKKERRQSLIFSMPAFIQKAGRINADSFNDNPYADQKMLELETLLQSASVKMNEEL
                     VALKKSMSMLPPQATISEVNCASPLNIGVFSRTPLGYRCVWLLVGFDQLAMQAFQAAH
                     YGFISRQELHRSLRRGGHLIRQIYGAAQKYRFFQVNRRDFALQNAQYHEAIRNAGEID
                     EAVLLGQKRSSFSPPVSKESIELLLAANAKADKADIVQLL"
     gene            complement(19752..21062)
                     /locus_tag="OPV72_001231"
     CDS             complement(19752..21062)
                     /locus_tag="OPV72_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR9913588.1"
                     /translation="MQTPAQVMEEPGSSVHRLPADDIIDYTLSKMQARLDGTPGSSGQ
                     ERNGLLFTGNIHDAYPRALILDMRLSPLDKMCWIMIRQYALQNDGAIFPSYDELQKLL
                     SSPGSGQASRDTVSRALTMLRLTGWLSLCKRVRDTGGRVRGNIYAQHDEPVSAKDAEM
                     FDPGWLDMVGKACQHKYREVSDTAFHVLNGILDDPMMRHRHSRMTEIAERLTRPSKVG
                     DVARTHQNPGTGLSLNSIKNEHKSLSPVNRPSSERGEKSPSPDSRLSLKSDSYDRVRQ
                     PDCNNVRSFTQSVIKKTYVSPQSGKNAVAGIPEGFVWPDGLQSILPESEQPMLAQQLN
                     QLAQKSPVQAEQIALSVVNGWHQKRISNPVGYLLTTLRQARAGLYRLEPAVTQPVKSR
                     SVVPAEPSAAGKIPTCSAEADVPAGQEVVKAMVEQIRQRMNSSQ"
     gene            complement(21092..21340)
                     /locus_tag="OPV72_001232"
     CDS             complement(21092..21340)
                     /locus_tag="OPV72_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913589.1"
                     /translation="MDSLAPSFQFYRTDPRNVSKAVTSKARTLLSLYQQGKRVYSQIG
                     QTGYLKIDLGLRWRLLSKDAGKSWLFMSHQTYNRELKR"
     gene            complement(21340..21897)
                     /locus_tag="OPV72_001233"
     CDS             complement(21340..21897)
                     /locus_tag="OPV72_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2857 domain-containing protein"
                     /protein_id="HCR9913590.1"
                     /translation="MTFSLAQGANSLLFNLVMELRGGNIRRCEALGLKPEEMRLLRSL
                     TMEELHYLSGSPVSVLNVAIHHENLKRMLDQANREQKRSERIDRAIALGASIEMMGIF
                     FGLNASDVSSKRRLEGIQTRQGRCQSPDEECEAKIWRLWHEANISDIESLNSLETMML
                     IAEEADVSLTVIWGLIKNWCTGEVA"
     gene            complement(21982..22704)
                     /locus_tag="OPV72_001234"
     CDS             complement(21982..22704)
                     /locus_tag="OPV72_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2786 domain-containing protein"
                     /protein_id="HCR9913591.1"
                     /translation="MSANEKVLSRIKKLMVLAEKTGNPYEASVALRQAQALMMKYDVT
                     PASVVPGEITSETCRNIPSNALSVPGWLNALVTVVCMTAGCRSYYGWYQNSDHKKRRS
                     VTFYGLGERPAVAGYLFGVVSRQLKRDAEHYLHTACAHPLLKLSTIRRRMDEYRLYWV
                     AGVWTVLESFEPETSEKVLLDRWLTQQQRNLTPAKVRQPEGCRNAKKVRQAAWTAGRQ
                     AEIYPAMDYRSEEHSLQEVSNG"
     gene            complement(22691..22951)
                     /locus_tag="OPV72_001235"
     CDS             complement(22691..22951)
                     /locus_tag="OPV72_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913592.1"
                     /translation="MKSLKKPRSHYQWVGATVVTTQELSSGLAVIPVGSRGVVNAAKR
                     GLSVIFDACPCCGVQLRLTRIRPEMLDIVAYPEIEEVTRVGE"
     gene            complement(22948..23175)
                     /locus_tag="OPV72_001236"
     CDS             complement(22948..23175)
                     /locus_tag="OPV72_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HCR9913593.1"
                     /translation="MSIDVDDSMAQNESQVNIDNRFAEIRAALRIKGHVSRRHCRDCG
                     DEIPDSRRESIPGVSLCMYCQEWRESGDKKQ"
     gene            complement(23165..24964)
                     /locus_tag="OPV72_001237"
     CDS             complement(23165..24964)
                     /locus_tag="OPV72_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB family protein"
                     /protein_id="HCR9913594.1"
                     /translation="MAKAPLLNLNNALLQGAKESSAATTAAVAIMPTSEMPMVLTLDE
                     VAPNPDNPRTTRNPKYDEIKESIRARGLDTVPKVTKNPDIPGSPYIFSDGGNTRYAIL
                     RELFAETQDERFYRFHALFKPWPGRLECLVGHLAENDVRGDLTFIDKALGIKKARAIH
                     EETLGRTVTLRELADLLGQQGYPIHNSMISRMEHTVEYLYPFMPELLVSGLGKPQIVN
                     LLNLRADALKIWQQYSVMTETDSDFNEIFGHVCTQFDDPEVYSFEMFRDEFIGMLVNV
                     LPHPSLNYDRWLLELDPKARNQRKLFGEPEPVASHLVDADRQTWQSTASLPGTANDEN
                     QQGGSSLKPKLNNAPVLPKQPDPDNDNGDNDDVTGEWFGSCGSPRLPKAEVQNDFLGG
                     PSVLTGDVIPDEYHFIPDAGNIAVSASAFAGAQVGLTADTPSDAVSIASEMPGLSLLP
                     TEPALSSVEFANVGLEPVTDIWVIPALQDDIEHLQDMAYRLAYELAEAMGCEVHVSED
                     KNASAAGFSVSEHGGEFALFLAGLSGHVPNKQFNMFMFCLNFFGSQSAGDTPVFDDVH
                     VVKSLRLIRVIRRLRELQRNMAAEQNDGRRHEH"
     gene            complement(24957..26321)
                     /gene="dnaB"
                     /locus_tag="OPV72_001238"
     CDS             complement(24957..26321)
                     /gene="dnaB"
                     /locus_tag="OPV72_001238"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000018526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HCR9913595.1"
                     /translation="MSHKSVSAVSMLFNVGAETGVLGGLMLDNDRWDEIAPLLNSGDF
                     YYGQHQIIFREIERLVSAGLPIDLITLSESMERKDLLERCGGVAYLAELSKNTPSAAN
                     IVAYAEIVREYSRKRRLVKLGHELHQLASVGDADIPGLIEKAEKQLFSLAQQACDPDI
                     CLSVTTQVADTVSWLESVSGGSGVTGTATGFAELDEKTCGWQDGDLILLGARPSMGKT
                     AEALKHAVAALEGSPGKTVQFYSIEMPTQQLIMRLLSMLARVPFDNLRKGLLSEGQWS
                     LLADAVAKLTSWEGRLLIDDTSYQTPSTLRISARRNVRKYGQPSLILVDYLQLMSCPG
                     RENRTQEIQEISRSLKSLAKEIRCPVAALSQLNRSVEQRQDKRPMVSDLRDSGSLEQD
                     ADVIMFLYRDEVYNEHSPDRGIAEIILGKQRQGPLGTVKVRFEGEYMRFSEYHLGYGE
                     VSYG"
     gene            complement(26318..27268)
                     /locus_tag="OPV72_001239"
     CDS             complement(26318..27268)
                     /locus_tag="OPV72_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HCR9913596.1"
                     /translation="MAQQVSPHSLLLPDEQQFPVVLPVVSTKGGEGKSTKAGNIAGYT
                     ADAGLKTLLIDGDYNQPTASSIFKLHYEAPCGLYELLMQTADLNKPDSIISRTVIPNL
                     DVIISNDPDDRLSNDMLHAADGRMRLRNVLQHPLFRQYDVIIVDSKGAGGVMVELVVL
                     AATQSVMGVIKPILPDVREFLRGTVRLLSKLLVLEPYGIHIPDIRILANCVEPTVLDR
                     NTLNELKAIVDKGQYPQSDRIAISMLNTEIEQLEVYKRGHACGQPVHRLEYKTDRVSL
                     PAAESMHHLVCELFPQWKDKFDAVLVNRPQPGFGQGADEV"
     gene            complement(27566..27640)
                     /locus_tag="OPV72_001240"
                     /pseudo
     CDS             complement(27566..27640)
                     /locus_tag="OPV72_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003842122.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT         6735 a         7817 c         6573 g         6629 t
ORIGIN      
        1 ttgaataagc cgccactcct gtagcagcat ttgcgcaaaa atagcaacac gttcccagcg
       61 cggaagcgta atgggagcga tccgacagcg atatcccgtc ctgtgtgaaa gaacctgaca
      121 ggtaagcgct acctgagctg gccgcataag atgtgaacgg aaaaaaacgg gacgcaccgg
      181 ccgcgccacg agggctgtct ccagtgcctg aacaaatgcc tggtgatagc gtcgggcctg
      241 gcggcggttc atcgccccca cccgatcaag caaggcaaga tgtacagccc agtattgacg
      301 gcgacgatac gttacactga atacagcaaa ccctttccag ggcgtgaaca gcgcaattaa
      361 cgtaaaacac gggcaataca gcgccagaca gaacatcaca aacaaagcgt actccacccc
      421 tctgtccttt tttgcagaaa atgaacggca gcagcgtacc cccttaacga cgagaataaa
      481 tcacgtaaat gactatccgt aacggcaaat ttatcaggca gcactcaaaa gaggatggat
      541 cattacccgc tcatgcttgc cttccggcaa atccccgggg cgaggcacac gctctccccg
      601 ctgagccgct ttagccagcg ttcgtagcaa cagaacacct gcagcctcca gcgcactctc
      661 cctcgatgcc gctgacactg aaagattgtc aaaatcgggt aggtgaacac gaaaaccaca
      721 acagccatct gatccttcat taacggattc aatacaggca ggataaggga caaaataggg
      781 agcaatcttt tgtgtttgtc ttcggcgagc gtcaagttta ctgacaagct ggtatgctct
      841 gagatgggta taacgtttga gcatattcag ggaacggtgg ccggaaatag ccgccacttc
      901 cataacgttg agtgttccca gttcaaacag tcggctaatt gcttcatgac gcagatcgtg
      961 aaaatggaga tcgacgatat tcaggcgctg cagagccacc ctccaggcgc ttttaaaacc
     1021 agatgatgaa tagtgaaaaa cattaccgct aagtgcgacc gtcattccct gtagcaaatg
     1081 acgcgctttg cgggataagg gaacatctcg cgaactgccg ttttttgtca ttggcaaatg
     1141 ggcaacgcca tgctgcaggt cgatatgttc ccatcgaagt gacaagatct ctccttgtct
     1201 cattgctgtt tcaatggcga ggtgaaatat ggcgtgaagc gctggattct gttcctggaa
     1261 gtagcgggat aagcgccgtt cctcttgtga tgttaaacgt cgatctcgtc ctcctgatat
     1321 ttttggctta cgaaccattt caacggggtt agttctgcat gttccccact ctacgctggc
     1381 cagattatac agtgatgaca gtaaagcgag ttcgagccgg actgtgtttc ctgaaataca
     1441 ccggccggta cgcgtattca cctgagacaa ccgatcatcg cggtaagacg caatatccac
     1501 tgtcgtgatt tcatccatca tcttctctgc caaaggatgt cgctgaatga ccctaacacg
     1561 atagaattcc tgctgatgcc cccgtttatg cacagacaca gtggcgtagt atttatcaag
     1621 ggctttcgac agagacattt tttttatgcg ttgtgggcga gacattgcag atacctttgc
     1681 gagaagaatt gaggtttttc tccaccgtaa cgaaaaactc taataccctc aatcctcgta
     1741 aggacatacg tgccaatccg gtatctgggt gtcgggtcaa aacagattca ctacacagct
     1801 ctacgacata gggcagaatg tgaatgcgca gtacataggc attcatgctt attgcagttg
     1861 gacacatcta ttttctgctc ctctaggggg gcgccagagg gtctacaatg tagggaacgc
     1921 ttggtatgtc acgaataccc cttacggagg ttttcaaaca ggatcgactg tttccgtaac
     1981 atgcctgaat ctgccgggtg cagggcttta attcataatc cggcgccagg taagttcaaa
     2041 caggttaccg aaatagtacc tccggattcg tagttccccc atctgtagtt agagatatac
     2101 cagccgttgg aaccgttcga gtgtatctcc tgaaacccgc ccagaggtga accattgaga
     2161 tatgtccatg cgcagtaggc atgcactcca atatactgat ttcttacatt tttaccgacg
     2221 ttaaatgtct gaatattaaa gttcagccga taagaactcc aaataccgga ttggcacgaa
     2281 agtgtggcac ctgctgtatc acgacttatt gcaccattta caggacaagc agtgctggca
     2341 acattaatct tatccagcgt taaaataccg cctgccgata cgtccccatc cgagcgaatc
     2401 ttcccaccgc gaatttcacc accggtataa aaccccttgt tattcaggat ccgtaaccag
     2461 tcgttatctg acatatacaa accaccacca tgggtctcat ccatccaacc tttaccactg
     2521 cgggttacaa tccatccccc tgtgcttcga atatctcccc ccgcagtgat cggaccatta
     2581 ctgaccagac ttacgccaaa attcccattc tggccagcca cattactggc cgtaacagtg
     2641 ccgacgctat tcaggttatt tcctcccata tcaatagctg tgtgcatctt gttcaaatcc
     2701 ggacgaccat tgacctgaaa acgatacagc ctgtccccgt cttcacgcgc ccctgacagg
     2761 tcatccgtgc tcaacatgac ggccagatga cctcttccgg tgctggtccc gtaggaggac
     2821 agcggaattc gccagctgcg catcgctccc accgccgttt gcccgtcttc aacgtatcct
     2881 ccgaagccgg cggtaatgtc tttcgagatc tggcttagcg ctgtaaaagg catagcatga
     2941 ccaccgcggc tgaccaccat gccctgaagc aactcctgat tttgctgatt ccggactatc
     3001 atcgcctgat actgctggcc ataactgttg gtctcactaa agctcgccgg cagcaaacct
     3061 gtattcttca gcatttgagt tgttaccact gcaggtgtag ttgtggtcgc tgatgccagc
     3121 accgtcggat aaaactttcc aacataggat gagactgcct gagtgaaacg attggtttgc
     3181 atggccacaa cctgccactc acgggatttc agataatctc ccatatatct ggcagccaac
     3241 gaggccatca ccagaacaat gagtaacccg gctcccacgc tcatcgccac aaagccgcca
     3301 tcatgttttt gttttttcat ctcagtatcc actcaggctg gtacaaccta tccacaatga
     3361 ctggtatgca ccctgcacac agccaggggc ccagaacccc acaacgcaga aagtcccgat
     3421 ggactatcca ctgccacaac ataaaaccac tcagcccaaa aaacgccgcc tgcagtgcat
     3481 ccgttacccc catccagcct accagggcac aaaccagcca gacatctccc acgccaagct
     3541 gaggtcgccg tcggttaaca ccgtgacaaa tagaccccat caccaccgcc atcgccgcag
     3601 tttccataaa gcgaagttcc ggctcccgat gaaaagcgag acagaacaat aatccgctac
     3661 ataaacaggc tgcggtaaac ggtcggggca accaaccgct ggtcgcatcc atcactccca
     3721 gttgcagcaa aaaactgcac ataaacagca ttccgatacg tgtcatccag acctgaggtg
     3781 ccataagtat cagcaaaccc gttaccgcaa acagccagat acccaccacg acggcacaat
     3841 ggcgtgagat atccacctcc gctgcggcca gataaagacg taccggcctt aaaagtaccg
     3901 ccccgaaaat ggcgcacccg ataaaagcag gtatggcata cacaggagga aaaatggtac
     3961 cgataagaga gactgtcatt gagcccccgt ttgccgctga taaattttcc agatccggtt
     4021 tgcataacgc tcccgtgttt catgccggtc aggccggaaa cctgcgttat aagagcccag
     4081 gcagttccag ctcaccccac agacctgaaa atgtttcgca aggatccacg ttccaatctg
     4141 cacattcagg cagggtttgt tcagcaaatc atttttgtcc ctgatgaccc ccatcgagac
     4201 aagacgggga atatgcgtag aattcaccat catcagtcca taatccgtgc ttttgatttt
     4261 ccccgttttt ttgtcccggt tatcatttgt tgcatgcgga tcaagattac tttcaccaat
     4321 ggccatggac ttaatcagca gcggggagac atggtatttc gccgcagcgg catcaaagca
     4381 gaatgcctgt acccacagcg gcacactgca cagcgtcatg aataaagcca gtcgggaaaa
     4441 atatccacac atcccgcctc ctcagccgtt gtagttaaaa accagcgtat tggtaccggt
     4501 ccggccatta tctgcagtgc attcactgct cgcgatttct gccgttactt tcgcatcggt
     4561 gtggttattg ccgtttattt taataccgga cgtgccgcct gaacggctca tacctgttga
     4621 aatggatacg caggcagatt gcggaacttt gtttgtggta atggtgaacc cattattaaa
     4681 tccggttccc cccgctgtat ccggcgccac cacaatctgg ccaccccatg agttccacag
     4741 tgtcgcggaa ccggaagcag ggtctccact gaccgtcatc ccttttgccg ccccggcctg
     4801 aattaacgtg tcggtcattt tagcgccact ggtaaaagca taaccgtcaa cgcctttcat
     4861 catgccaatg gtgttcgtgg ccagggtctg atagtttgtc agctccgtac ccgcatcctt
     4921 tttaccccac atcgaccaga ccgccgcggc tatcacccca atgatcacca gaataaacag
     4981 tgcagtggca ccggcatctg ccgacattcc ccggtcaggc ctgttgcatg gatttaatgt
     5041 tgatacctca ttcatcatct ttccctctgt ttcatttttc attgaattgc ttaacatcag
     5101 tactgcccca tactctcggt catcgaagtc gcctcaatca ccgccacgac cacaacgcca
     5161 ataagcgcaa ataacatcac cattgagaac agcatcacgg ctattccccg tcggttaact
     5221 cgcttcacag tttcctcgag ccattcctgc ccaaagcgcg caatcatctg agcggccccg
     5281 tccccactga ccatagagag atagttcacg gcttcttttg aggggaaggc ataaccacat
     5341 tcacgcagcg ccataccaaa agaggccccc tcctccactt cctccatcac tgcgttcaga
     5401 cgtacaacga gccagggaga agcaaagcgg tggataacct gcagcgcagt cagggttctg
     5461 accccagcgc acagcagagc ccccatattg atgagaaaaa tcgcgccctg aatatcactg
     5521 taaaccgccc agggtacatg tctgtccgca agacgacgca gacggtccgg acgtatccag
     5581 ttcgacaggg accacctggt ccatgcgacc aacagtgcca gcccggcccc catcaccacg
     5641 ccatgctcag taaaaaaaat cagcaggccg ttaaggcttc ccagcactcc ggtccatgtc
     5701 tgcggatctg acatcccggc cagcgttgga ataagctgcg tctgaataac acccagcgtg
     5761 ccaccgagca tcgcaatgca acctagggga taaacggcca tcctcatgat cgcctgtcgg
     5821 atacgccgcc ggcagtcaat caggatttcc gcctctgcga gcgcctcagg taaccgacca
     5881 ctgaacatac ccgcgctgat gagcgccgcc tcctccgccg gaacccagtt tgcaagagca
     5941 tgctcaaggg agttatcccc gctgttgtca gtgagtgccg cccggcagtc gtccaccaga
     6001 aaaccgaaac catgagtccg ctgcccaaaa tcggtataca tattgctgat ttgctccagc
     6061 gcctctaaca acttcacgcc atttctcatc tgcaacgaca gcatgcggta aaaacgcaga
     6121 cggtatccgg acgtaaaaaa acgtcgcgcc agcgcccggc gaagacggta taaaggactc
     6181 atgcaacctc cttcagcgca gccatcccgg cagcaacgcc ttctttaatg gcttcctcaa
     6241 caccctgctt catcccctct ctgacgctgg ctgcaattac catggcaagg cgttcaatca
     6301 gcgacgtatc aatgtcactc gacgatgcaa cctgatcact taccacctgc atcacctcat
     6361 cctcatcaag aggaataatc aaatcggcat ccagtgggtc aaccagcccg tcattcagtt
     6421 tgtgaagcag atgaatgcga cgggtaatcc cccccatttc acggatccag taagcttttg
     6481 cagcttcctt accctgctgt aataacagcc tgaaaagcgt agaatccgtg cgaaccacct
     6541 ccgccaccac actgcgtccg gccaccccct taccgactgt tgccacctgt ttgccaccga
     6601 taatgaccgc cttccggcag gtcgggcacc cctcctcatt tctgaaatga agattttcgg
     6661 gctgacaaac cccctccact gaacagtact tttccagata ttcacgttct tcggtggtga
     6721 gatgttcttt tttaaccgac cagggaatac ggcactcggg acacagcacc tgaaccagac
     6781 gctggctgat aagcccgacc aacaactggg catctgccac cagtccggca tttgcaccca
     6841 tcgttatcat tcgctcaggg atggaaaagg ccgagtttga atgcagggta ctcagcacca
     6901 gatggccggt ctgggcggca aaaatcccgg ccagaatgga gataaggtca cgaagttcac
     6961 caggtaaaat ggcatccgga tcgagacgta acgctgaggt cagcacccgc tgccaggcca
     7021 gcctgacttc cgcctcatcg gctttgtcac agataatagg agtctgtatt gccccaacga
     7081 tgcgtccctc cggcggatct tcaaccgtca gtaggcgctt tttataccgg gtacgcttca
     7141 gatagaggtc gctgcaggca cgcagggtgg tggatttccc ggctccggtc gggccggaca
     7201 aaataatcat cccttctggc aggcgcaaag tgcgctttat caggcggatt tgtttcggca
     7261 gaaaaccgag tttttcgagc gtgggaacca catcaccatc atccgggatc acgcgcatca
     7321 caaagtgaag gccatctgct gtcggggtgt ggctgtaacg ggcgccaaat aaccccacct
     7381 ttcgcagaaa ctttgcagcc acacgaccat cctgttttcg gccggcgtag aactggggtt
     7441 cggtcacatc acacatggaa aggatgatag tggccgcctg tgcttttccg tcttcttcag
     7501 ccagttccga aacggtctcc agttcaccgt gcacacgcat ctcgatgcgc gtcagtcctg
     7561 gccgggtggt accgtgaata tcagacgcgc cgatatcttt cgcgaccata aaatagttga
     7621 gaacatcgcc ctgacggctg ctgacctctt ttttgatgtc ctcaaggcga agtccttttt
     7681 ctcccttctc tgactgctgg cgagccattt cactgtacct gagcaactct gaacgggtta
     7741 ccagcctcat tgtgacaccg gggttttcct ccatcagaga cattaccttc tgctgcaccg
     7801 ccacgtcggt acgccgctgg ctgtcaacca gcagctcgag gatcgtggtg tccgggttgt
     7861 ggtaaagcag aaccgcatcg ttgtgttcag acataattcg tccctaaaac gtcagttgct
     7921 gaccgtcact gagcgtgacg gatgagagcg ttattgcctt caccttcagt gatgtccccg
     7981 gaatcacact tcccgtctgt accaggcttt gtcggccatc cggaaatgac agcgtggcct
     8041 gcagggcgtt accacggcca ctcacttcca gaaccgtaat tcgtccagtt gcaggggggg
     8101 tgtgaacagg agtcgcattc atctctgccg gcattcccat aacgaacgga ctggtcgtgg
     8161 gcacattgcc aacatccccc ggagtttgtg cagaagtcag ctcttttagc agtcgggctg
     8221 cctgaacctt tgcctccagg agcaggtttt tcccctgcag cgcctccagc tgtccggccg
     8281 tcacgctgtt accggggaaa atggggactg tatctgataa gtctgcagag gatatcgatg
     8341 ccgctgcttc cgtagcgggt tcactggcag gcattgcaga aatcacctct gcggaaggag
     8401 gaactgcgag tgtgggctgc gaaaatgccc ctgcgctgaa cgccatcagg agaacaccac
     8461 tgatgaaaac actatttttt ggcataagca taaagatgcc cctcaatctg ataagtaaac
     8521 tgtccctgag gactcagggt gtaacccaca gaactcagcc gtaccccctg catatcgagt
     8581 ccctgtaaaa tccactcagg catgtgttta tcagtgatac tgaacgtgta ttcatgccag
     8641 tcctgtatcg gctggggcgc atcgttgccg gcaccatcac cgggcatcgc gggaggagtt
     8701 ttcacttcgg acagagaaaa actgacctgg cgtgactgaa accacgacac cgcctgcatc
     8761 aactgggtcc ccgcatccgg cgcagtctca tcctgtaatg tgaatttcgc ccatggaata
     8821 aacaccacac cttcgttgcc acctgaaaca aggttgaata ctggtgtacg cttaaaaacc
     8881 tgcttcaccc gctccgcaaa gcctgccgcc gtcccaccgg gctgccgctg gtacaccgtc
     8941 tccagcccct cagcactgca acgaatccgt tcgagacgcc aacggtcaag acttacagga
     9001 actgcggcgc gccagcgctg acagcggttc agaaagtgtc tggccacagg catatctgcc
     9061 cagggatgtg gaaggtaaac aggttcaggt gtttttttaa acacgtcctg caccggtgcc
     9121 ggtaactcct gcacgacagg cgcgaccgga ggttcgggta acctgctcca ccagactgca
     9181 ccaccaagca gggcagccac tgacagcact cccgccccgt atggccgcaa aggattagac
     9241 acgcccgcca ctctggcaaa ccggagctgt gccgaagata cctgaccgac caaagtgttc
     9301 caggacaagg ggaattccgg tgatgaaggt atcgtccatc cgtcctcagg agcagggttg
     9361 aaggacagaa agagctctct cgcccggatg atttgatctg gagttccgat cacatctgcc
     9421 atcggagatg gcatcccctt caccgtggcc agaaagacct gtctgccatc atcaagctgg
     9481 tataccccat agccattggg tgtacactgc tggctgaaca gcgccgccag ggaatacagc
     9541 ttctggtgac gccagccggc ctcaatttgc cccaacgcgg tcaaccggct cttgccctgc
     9601 ttcaccgtca acacaacgtt cagaacaccc cgacgttgta caggggctcg acgtaccgac
     9661 ttttgctttt cttcccagcg aagccccgct acccagttct ggcgctgcca gcgcagaacc
     9721 tgcgtacggg gcttgccgga taacggaata tctgccatat cagccaccgt tccccatcag
     9781 ctccggggtg ataataatga ccagcgtact acgagaatca tcgccgtccc gaccgccacc
     9841 cagcaggaaa ttacccgggg taaaggtgcc gtttttggtc atccgggtat tactctgatc
     9901 aaaacctgtc agcaccagtg cctgccctgc gcgaaggtta gttttctggc tgagcgagcg
     9961 gagtttggtg tacggcatct cgatgtacga gttgccgtct ttggacgtga agttacgaat
    10021 agtcggtggg tcagacaggt tgaatgccac ctgcagttgc acgtcaccac catcctgaat
    10081 cagtggcagt aacgtcatgt tgaagccggt agtcatcata cccggcgtca gggatgtggg
    10141 cacccacatc ggttgtggta gtagttgaac tctgtgccac gtagaccgtc tggtcggcca
    10201 tctgaatagg tacaggtgta aggttcgtgg tcacgctacc ctgcgaggtg accacactga
    10261 catcgccctg ctctgacaga gctttaatca gcagactgga gccggcaaat ttagccgcac
    10321 ttccggttgc tgaatccaga atagataccg acgccgacgt tgcgttggtg atatcaccac
    10381 ttacattatt gagtgaagca ccggctgagc gcagggactt gtaaacgata ttccagtcca
    10441 gtcccagttg ttccttacgt gaagtactga cactcagtac ctgaacgttg agcctgacct
    10501 ggcggttcat ctgacggttc tgctgctcaa catacgccgc gatactgttg agtacagaag
    10561 gggtatccgt taccgtcaga gtgccggtac tggccgacag ccagaaacgt cccttttgcg
    10621 gagtcaccat ggtttccagc gtctttttca tatcgtcata gacattacgg ctctggtcga
    10681 ccgtcgtctg ctgcgaagag cttgaatccc ctgacaccga actgtttgta ctgccaccac
    10741 tggttcccat actgcttgtt gaacccgagg taacactggc attactggta atattggtat
    10801 tcagaaatgt gaactggaaa gtacgcgtct ccaggagtga aaacagaatt gccccgttat
    10861 ccatacgcgg ggtgaggcct gtcctggccg aaatcatgtc cagcagaccg gacagtttgc
    10921 cctgccagcg caggccactc agtaccactg gtgtggcggt cgcgcgtgcc gaatcaacag
    10981 cgccgcccag ttgatccaac ggaattcttc cattgttatc cggtgtggct tcggggttgc
    11041 ctttaccggc aggtattcag aacggggatg tggtctacct caattaggaa aatctttaat
    11101 gataagaaaa tattacaaag tcaggctccg tattgcagct acagccatcg tcgccgcact
    11161 ttcgctgccg gcctgtactt ttcaggaaat ggacaggatg tcgcgcagtg cgcaagccag
    11221 cggtgatatt gcccgcggtc atgtcagtga gcagatgcga tcctcacagg gagcgctggt
    11281 ctggacggat aaaccctggg tcaatctcaa acccgtcccg acagtgtcac ggggtatccc
    11341 tcaggaaaac ttccctgact gtcagataac gctggcacgg gacggactga ctctgccgga
    11401 agttggagag cgaatcactg cgctttgcgg cgtcagggta attttttcac ccgatgcgct
    11461 ggcagcaggt cagtcgtccg gtaccacgcg ggcactgaat ggtccattac cgataccgga
    11521 taaccagacc agttgcccct gcgtcaccgt gccagttaat gccgacccac ctgactgttc
    11581 acgcagcgca tccaccagac ccgggacttc aggcatccag acccacagcc ggttagccac
    11641 aatgacatgt cggatacggc tgtcaggagc caccggcagg gccagttctg acaaggcgac
    11701 cgttccgtcc gtcagggtat gtcggtagcg ccagtcatta attcccgcag ccagcaataa
    11761 catttgccgg gccaacagat acgaactccc cgactgctgc gctttgacaa cctcgcttcg
    11821 ctgagtggtc tggacatgtc cgacgacaag cagaaatact gtgcccagag cgacaatgaa
    11881 ccagcccata gctacgaccg gtcagccggt ttatccgcaa ctgaaaccag gcactgcagg
    11941 cgggaagctt cagcaaataa gggcttgtca gctttcttat aaaggtcaaa cacctgaacc
    12001 agcgccgtct caaagttgcc tttaaatacc aacggtgcgt caatgcggta atccgtaggg
    12061 gtctgccaga taaccaccca gtgtcctccc cccggacagt cagctcttcc ggcccagtca
    12121 gtcagggact ctttgagcgt gctgccgaca accgccttcc actcagggcc actggccact
    12181 gcagctacag gcgtaccggt taacggtttt gttgtcgtgg ccagtaccgt agccgtcgcc
    12241 ggatttacag ccttaacggt tgagggagac ggtgttttag cctgagcctt ctctcccaca
    12301 ggcgccggtg aatgagacgc cgacagggtg gtcccggtca ggttttttcc tgtgaacgga
    12361 ttgcgcggag ccggagaaga gacttgtttc acgggggggg cagaggacac tcctgacgtt
    12421 accggtgtcc caccaggtct cagggcaggg acaggaagtg actgactgac cggtttcagt
    12481 tcagtacctt tcttcgccgc caggtgctgg ccggcgatca cgggttcagc tttattcccc
    12541 ggcagaacgc cggtataagg attgcgggtg gtttccgggg aggaggttct tgcggcgccg
    12601 gtcacggcgg gtgtgacaga tgtcagtgct ttagttttag cctgtacccg atatgcatca
    12661 cgcaatacga aacagacctc ccggttgact tcatccacgg acattcgcca ggcaggaccg
    12721 gcgaccacct gcagtgcctc actgagtcgc atcggcccaa ttttgcgctg aacggccggt
    12781 aacggccggt tcagcagctc agaaaagtca gcaccataat gtccgcacag ggaataacca
    12841 gactgaaaca gcaggtagcg aaatccgtca ccgactgagt taaccagttg ccctggcata
    12901 gtaatatcga tgagctggtt gagcggttcc cgctgcgcat ccgcactttt aatactgacc
    12961 agcgtgtaac gcccgctgcg agtcacctcc ggtgatcgct ggtaaatatc agagaagacg
    13021 gaaggctgct gactctgtgc aaatgcgctg tcgcgagcgg tttgggtgga ggtctgctgt
    13081 gcacacccgg caatcaccag cggcaggctc aggcagaaaa gcgcttgtgt gttcatgaaa
    13141 aatcccgtgg atgaccgtaa ttacggcaat cgtgcggaga tttggcttag cgctcaataa
    13201 acaactcttt atgcaaaaat gaaaaaaaaa gccagcatca ttgctggcat tctgcataca
    13261 tgaatttact caatgtaaag aaggtcgata accctcgatg ttaatgacgc ggttgttcca
    13321 gcgtctcgcg gttcagacct gtggatttaa tcaccacttc caggctgaca ccattgtcaa
    13381 gcaaggcata cgcagtttcc agtaacgtct tctgctcacg ctcaaggctg gcctgacgct
    13441 cctgctgaat actctgctga ataccctgct ggataccttc ttctttcagt tgctgtgcaa
    13501 ttgtgcccat gatcaactcc ttatactccg ggatctcacc ggccagttcg tataaaaacg
    13561 gcgtgatact ctcgcttgtc atgccattgt agataatata acacaggacg gcttccacct
    13621 gcgcccgggt atttccggct agtcaaatca gctgtacaac atcacgcagc agcgatgcag
    13681 cgtcgcgatg ccggatatcc cgctgaacca gctccagtaa tgccatacga cggtgagact
    13741 gcaggtcgca gtcctccatg acgctgacat ccaccagggg ccacggtcgg gagtaaacct
    13801 cccgcgccag cgccggtaca tcgaaacagt ccatccagtc tgtactgtat gggtaaggcc
    13861 gcaccattcc ctgataaaac agtaacggca ccaccaccgg cagtgtcccg ttaccctttt
    13921 tcaggtgggc atccatcact gccatcgagt aacgcatcat ccgccaggcc atcatccggt
    13981 ctgcggtcga ctggtgttcc acaagacagt atatgtaccc ggcgtgacct tctgcggttt
    14041 ccaccgaata cagtacatcc gagtgcagtt cgcgaagctt ctgatccaca aaactacccg
    14101 gttcaagctt cagcgtatcg agacgaacct gcgcgcggat atctgcggga agatgaactg
    14161 ccaggaaatc cctcgcagtg tccggctcac gcagaaaaag cttaaacagg ccatcgtgcc
    14221 cgggccggtt atgacccttt tcgttatcca ttccgtatcc ttcatatgtt caaaacataa
    14281 tgccttccac aggaaggcat tattcagcga caattttcag gacagcacat aaagcgcatg
    14341 tctggccaca ctgtgcccga acggcgcgaa cgggatatca tcgtcgaagt ccattggcgg
    14401 ctcatttgca ggatgctgtt gaggtggcat cccgctgtga gaaggcgctg ctggttgctg
    14461 aggctgaccc cagccgccct gttgctgccc acttcccgca ctatttcgtc cgcccaacat
    14521 ctgcatcgta cctgactggc tgacgaccac ttctgtagtg tacttttcaa cgccagactg
    14581 atccgtccat ttgcgggtgc gtaatgcacc ttcgatgtat acctgggagc ccttacgcag
    14641 atactcactg gcaatttcgg ccagcttgcc gtaaagaacc accctgtgcc attcagtgcg
    14701 ctcttttttg tcaccggtct gtttatctgt ccaggtatct gaggttgcca gactgaggtt
    14761 taccacggca ccgccatttg gcatataacg cacctcagga tcctgtccca gatttcccac
    14821 cagaataact ttgtttacac ctttagaagc catgagtatc tctccttaag cctgttcacg
    14881 ctgtgaccat gtgccctgtt tgagcgcatg ttctgcctga gactgagtgg aaaagtactc
    14941 aacagattca cgggataccg gcccttcttc attttgcgtg ccgatgtaat atccggcacc
    15001 actgcgaagg acctgtaaag gtaaggataa cccggcaaat tttgctgcca gtaaaccagt
    15061 agaagatgat ggtgaagtta acattgattg ttccttttac attaagtcag gaacacacct
    15121 tcctgacgga aagtgtgttt ccatcaggaa gggttaagga gaactcagaa cgaatcttcc
    15181 gcgtactgct tctgcgcggg ctggctctgg gccggaggag tggaatccgg tttttctgcc
    15241 ttatagacaa ttgcaccgtc aatttttatc cagtcaaccc ggatgaggcg agtcttcagg
    15301 ctgacacggt tttcaccggc atgatcacct tttgcaaggg taaaaatatc ggatttgatc
    15361 ccactgagaa caaaaccgat cattactttt ttgtcctcat cacaggactt ctggcagcgg
    15421 ttaattaaac tcgttgcgtc tttgcctgcg actgtgacat caaagcgggt gtagtctgca
    15481 ttatctgtcg gaccactaag ggcattcagc gtacaacagg taaacttact gttaccgttg
    15541 acaacctgac gtacattcgt gatatagccc agaccgttga tattcagatt aaagtagtta
    15601 gtttctttag acatgatgtt tctccatgga atgaaatcgt tgcggagaaa acatctaccc
    15661 tggcgggatg atggattccc gcagggatat caacgctggc aaaacgctga tgatcaataa
    15721 gtttaaaata tcttcatcgc aaaatgctgc gacagccgtt tccaaagatt aaagggctgt
    15781 accacccgaa ggcgtcacct ctcaggctac gatgacattg gtgtgcaatc acccgaaggc
    15841 gtccctctca gattgccgga acattggtgt tgtgatcacc cgaaggcgct cctctcagat
    15901 cactggaaca ttggtggtcg ctaagcgaca taaggttcgc gaccattttt agaacattag
    15961 ttaaccctgt caacccgtta aatatttttt gtctcgccat aaaaaaatgg ccctcgctaa
    16021 cgcgaaggcc atttctcaac caaactgttg caccagaaca tgaggtaaaa tcaaatctcc
    16081 gaagccggtc aatggctcag cgcggttttc acggagtgat tgcgctttga ggacggatcc
    16141 ttcgagtaaa gatcgttctc ctgactggag ttgcgaaagg catgcaaagc tttcgaaccg
    16201 ttccacagcc atgggtgctg ctcttatcaa agcgatataa ggctaccaga attcagcgaa
    16261 agaaaacaac ccgttagtat tctaggctgg cgaaggtttt cgtctgcgtc ctctggggcc
    16321 cttgttacca ttgttcacga tacctttgca ctccggatat ttcaggcagc cccagaacaa
    16381 gccactcttt ccattgcgct gcaacgtctt gccgccacat acaggacagg gtggtgaagg
    16441 tggcgcctgc atagtcagtg gctgtgatct cccctgagcg accagctgac tgacccactg
    16501 actttgcttt gccataaagt catccaggct caccctgcct gcagctacct catccagcat
    16561 ctgttcccac agtgccgtaa gtccgggatt cgttaacgtt cctggcaaca catccaccag
    16621 gttacgtcca agaggtgttg acttaagcgt ctttttctca cgcaccagaa acccacgctt
    16681 caacagcgtg tcgattatcc cggcccgtgt tgcttcagtt cctatccccg cattctcttt
    16741 gagcaccttt ttcagcgcgg cgtcagtaac gaacgccgcc gcattggtca tcgcggcaat
    16801 aagagttcca tcgttgtacg gagcaggcgg ttttgtctgc agtaccttct gctcagcgcc
    16861 ctgcacctgg cagacctggc ccgcctgcat ggcgggcagt gtggtttcac cagtattatc
    16921 ctcatcatct tcggacattt tgccaaacag agatttccag ccgggtttca ccaaaacgtt
    16981 accacgggta cggaaaagct gaccgccaat attaaatgtg gcctcagtca cgtcaatttc
    17041 catctggggc aggaactggg ccaggtagtg caacctgacc agctgataga cattgcgctc
    17101 agcatcactg agtttgctca gatcaccagt atgttttgtc ggaatgatac cgtgatgagc
    17161 ggtaattttt ttatcattcc agatacgtga cacaaactga gtgtccagac tcgcgaccac
    17221 cggctgtagc gccggatcag ttccgaccac agcagacagt acctgtggga tttcttctcg
    17281 catcgataac ggcagataac cacagtcagt tctgggatag gtcgtcagtt tgtgggtttc
    17341 atataacttc tgggcgatat caagtaccgt ctgggctggc atcccccagt gtcgggagca
    17401 ggcctgttgt agtgtgctca ggctgaaagc cagcggcgct gattgttttt tcctctcgat
    17461 ctggcaattg attatcgcag ccgttggcgt ttgccgacac aactgaacca cctgtgccgc
    17521 tacccccgac tggatacaac gcttctcttc atcgcaatac tgtgcagccg gtacccattt
    17581 ggatggaaac aacacgccat tcacggccat cgtggcaata acttcgaagt acggtttcga
    17641 cacgaagtta tcaatttcac gatcacgctt taccactatc gccagcgttg gcgtttgtac
    17701 ccggccaact gaaagtacgt taccgatacc cgcttcacgc cccaggagtg taaacaggcg
    17761 agtcagattc ataccgatca gccagtcagc cctgctcctg cccacgccag cataataaag
    17821 cgattcagtt cgggaagacg gccacaaatc agctaacgct gaccggatac tggcatcatc
    17881 cagagctgac atccacaacc ggaatacacg cccctgaaac ttgcagtaat ccagcaactc
    17941 acgggcgatt acttcacctt cccggtcagc atccgtggca attaccacct catctacctg
    18001 tttaagcaga cggttaatta ccgcgaattg ggcttttgca tccgctttga ctaccagttt
    18061 ccactgctgt ggtaataaag gaagcacatc ggtgcgccat ggcttaccat actgttcgcc
    18121 atatacttcc ggttcagctg tctccagcag atggccgcga gcccaggtga ctgtaactcc
    18181 cggaccattc aggaatcctt cgcctctttg agtggcgcca agaaacttcg caatatctct
    18241 gccctgagaa ggtttttcac acaacaccag acgcatgata acactccttt cagaaaacca
    18301 gcctttctgc gggcttaacc atcgatgcgt ttcgaatcag cgacaaataa agaagggtca
    18361 gccacaatct gttcttctaa cggttcttac agtaattgca caatatctgc tttgtctgct
    18421 tttgcatttg ccgccagtag aagttcaata ctctccttac tgactggggg tgaaaaagag
    18481 gaacgttttt gccccaacaa aacagcttcg tcaatttcac ctgcgttcct gattgcctca
    18541 tggtactgag cattctgtaa tgcaaaatcg cggcggttca cctgaaaaaa acgatatttc
    18601 tgagcggcac catagatctg acggattaga tggcctcccc gtcgaaggct acggtgaagc
    18661 tcttgccggg agataaaacc ataatgcgcg gcctgaaaag cctgcattgc cagttggtca
    18721 aagccaacca gaagccatac acatcgataa cccagaggtg tacgactgaa aactccaata
    18781 tttaaaggag aagcacagtt gacctcagaa atagtcgcct gagggggtag cattgacatt
    18841 gacttcttga gtgcaacaag ctcttcattc atcttgaccg aagcggactg caaaagtgtc
    18901 tcaagctcaa gcatcttctg atcagcatac ggattgtcat taaatgaatc ggcattaata
    18961 cgacctgctt tttgaatgaa ggctggcata ctgaaaataa gactctgacg acgctctttt
    19021 ttcttcccct ccttttcccc ctcttcttcc ggaggacgcc cctgccacaa atttattgca
    19081 taatcagtat tcaacgctat gttcagcgcc gaacgtaaag cacccgcttt tctggacact
    19141 gatacctgtt ctttctcact catcaccaac ccctcaccat cgaataaaac gtatttagtg
    19201 agggcgataa ttagtcaggt aagccagaag tcacaatgca aaattcttaa tccaaagatt
    19261 aggttttcaa taagtggtcg ttttgtacta tgcagtctcg ggcagtaaag ctcatttttt
    19321 aaccaacaag ccttctggca gacccaaata cactcactgg ttatttttta taccatgctg
    19381 ccactggcag caaagctcat tttttaacca atacattttc tggcagaccc aaatacagtc
    19441 tctggtcatt ttttataccg tgttgccact ggcaacaaag ctcacttttt aaccaatata
    19501 ctttctggca gacctaaata cagtctctgg tcatttttta taccatgctg ccactggcag
    19561 caaagctcat tttttaacca atacactttc tggcagacct aaatacagtc tctggtcatt
    19621 ttttataccg tgttgccact ggcagcaaag ctcatttttt aaccaacaca ctttctggca
    19681 gacccaaata cagtttctgg tcattttttg taccatgctg ccactggcag caaagtatat
    19741 tttttaacca gtcattgaga ggaattcatt ctctgacgaa tttgctccac catcgccttc
    19801 acgacttcct gacctgcagg gacatcagct tcagctgagc atgtcgggat tttcccggca
    19861 gcggatggct cagctggcac gacagatctg ctcttaacag gctgagtgac agcaggttcc
    19921 agacgataca gtcctgccct cgcttgcctg agtgtagtca gcaagtagcc caccggattg
    19981 ctgatacgtt tctggtgcca gccattcacc acgctgaggg cgatctgttc agcctgaact
    20041 ggtgatttct gtgcaagctg attcaactgt tgagccagca tgggttgttc actttccggc
    20101 aggatggact gcagaccatc aggccacacg aacccctcgg gtattccggc aaccgcattt
    20161 ttgccactct ggggagatac gtacgttttt ttaatcacac tttgtgtgaa agaacgtacg
    20221 ttattgcagt ccggttgccg gactctgtcg taactgtctg atttcaggct gagtctgcta
    20281 tccggactcg gtgatttctc ccccctctca ctactgggtc tgtttaccgg actaagtgat
    20341 ttatgctcat tttttatgct attcagactg agtccggtac ccggattttg atgagtgcgg
    20401 gcaacatcac ccaccttgga cgggcgggtc agacgttccg caatttccgt catccgcgaa
    20461 tgcctgtgac gcatcatcgg atcatcaagt atcccgttca gtacatgaaa ggccgtgtcg
    20521 ctgacctctc tgtatttgtg ctggcaggct ttacccacca tatccagcca tcccgggtca
    20581 aacatctctg catccttcgc actgactggt tcatcatgct gggcgtaaat atttccccgt
    20641 acccggcccc cggtatcacg cacccgcttg cacaaactca accagcccgt tagtcgaagc
    20701 atggtcagcg cacggctcac cgtatcgcgt gacgcctgtc cggaaccggg ggaagaaagc
    20761 agtttctgaa gttcatcata tgaggggaag atggcgccgt cgttctgcag ggcatactgc
    20821 cgtatcatta tccagcacat tttatccaga ggagaaaggc gcatatccag gattagcgcc
    20881 cgcgggtagg cgtcgtgaat attacctgta aacagcagcc cgttacgctc ctgccccgac
    20941 gaccccggcg taccgtcaag ccgtgcctgc atcttcgaca aggtgtagtc aatgatatca
    21001 tctgcaggca aacggtgaac ggatgaaccg ggttcttcca tcacctgagc cggagtttgc
    21061 atcgttcttt ctgttgttat cgatgcgtct ctcatcgttt cagttcccgg ttataggtct
    21121 ggtgagacat aaataaccag cttttacctg catccttact cagcagacgc cagcgtaatc
    21181 ccagatcaat cttgagataa cctgtctgtc ctatctggct gtagactcgc tttccctgct
    21241 ggtacaggga aagcagtgta cgcgcctttg acgtgacagc tttactcaca tttctcgggt
    21301 cagtacggta aaactgaaag gagggtgcca gtgaatccat caggctacct cccccgtaca
    21361 ccagtttttg attaatcccc agatcaccgt gagactgaca tcagcctctt ccgcaataag
    21421 catcatagtt tcaagagagt taagactttc tatatcgctg atattggcct catgccagag
    21481 acgccatatc ttcgcttcac actcctcatc aggtgactgg caacgtccct gacgtgtctg
    21541 gatcccctcg agccgccgtt tagaactgac atctgaagca ttcagaccaa agaagatccc
    21601 catcatctct attgatgcac caagagcaat agcacgatca attcgttcgc tacgcttttg
    21661 ctcacgattg gcctggtcca gcattcgttt tagattttca tgatgtattg ctacatttaa
    21721 aacagaaaca gggctgcctg acagataatg cagttcttcc atcgtcagac ttctgaggag
    21781 acgcatttct tcaggtttca accccagcgc ctcacatcgc cgaatatttc cacctctcag
    21841 ttccataacc agattgaaca aaagactgtt ggcaccctgt gcaagtgaaa aagtcatatc
    21901 gcctcctgaa cgtgaacact ttcattatcc aagacaatta attgattaca ggcccctgga
    21961 gcgagaataa acgccagaac gttaaccatt ggatacctcc tgaagcgaat gctcctcact
    22021 gcgatagtcc atagccggat aaatctcagc ctgcctacca gctgtccatg cagcctgcct
    22081 cacttttttg gcgttacgac acccttccgg ctgccgtact ttcgcagggg tcagattgcg
    22141 ctgctgctgt gttaaccagc ggtcgagtag aactttttct gatgtttcag gttcaaatga
    22201 ctccagaacc gtccatactc cggccaccca gtacaaacgg tattcatcca tacggcgacg
    22261 gatagtggaa agtttcagta acggatgtgc gcacgcggta tggagataat gttcggcatc
    22321 acgcttcaac tgacgggaga caacgccaaa cagataaccc gccaccgccg gacgttcacc
    22381 aagcccgtaa aatgttacgc tgcgacgctt cttatgatca ctgttctgat accagccgta
    22441 atagctgcga cagcccgcgg tcatgcaaac cactgtaacc agagcattca gccaacccgg
    22501 aaccgaaaga gcattactgg ggatattcct gcaggtctca cttgttattt ctcccggtac
    22561 cacgctcgcc ggggttacat cgtatttcat catcaatgcc tgggcctgcc gtaaagccac
    22621 tgatgcctca tagggattac ctgttttttc ggccagtacc attagcttct tgatacgtga
    22681 aagaactttt tcattcgccg acacgagtca cctcctcaat ttccggatat gccacaatat
    22741 caagcatctc aggacgaata cgggtcagcc ttagctgaac accgcaacac gggcaggcat
    22801 caaatattac cgacagcccg cgctttgctg cattcactac gcctcgactt ccgacaggaa
    22861 taaccgccag tccactgctc agctcctgtg tggtgacaac cgtggcaccg acccactggt
    22921 aatgtgagcg gggctttttc agactcttca ttgttttttg tctcctgatt ctcgccattc
    22981 ctgacagtac atgcacaggc ttaccccggg gatggactca cggcgcgagt cagggatttc
    23041 atcaccacag tcccgacaat gtcgtcgtga tacatgtccc ttaatccgaa gagcagcccg
    23101 gatttcggca aacctgttgt caatgtttac ctgcgattcg ttctgagcca tcgaatcatc
    23161 aacatcaatg ctcatgcctc ctcccgtcat tttgttcagc cgccatattt ctctgcagct
    23221 cgcgcagacg gcgaataaca cgaataaggc gcagactctt cactacatgc acatcgtcaa
    23281 aaacaggcgt atctcccgct gattgggagc caaagaagtt gagacagaac ataaacatgt
    23341 tgaattgttt attcggcacg tgaccggaaa gccctgccag aaaaagagca aattctccgc
    23401 cgtgttctga aacagagaac ccggccgcac tggcattttt atcttcactg acatgaacct
    23461 cacagcccat cgcctctgca agttcataag caagccggta agccatgtcc tgcagatgtt
    23521 cgatatcatc ctgcagagcc ggaatgaccc agatatcagt aacaggctcg agccctacgt
    23581 tggcaaactc aactgaggaa agtgctggtt ctgtgggtaa aagtgagaga cccggcatct
    23641 cgctggcaat actaacggcg tcagaaggag tatccgcagt caatcccacc tgagcgccag
    23701 cgaaagctga tgcactgaca gcgatatttc cggcgtcggg aataaagtgg tactcatcag
    23761 gaataacatc accggttaaa actgagggcc ccccgaggaa atcgttctgg acttcagctt
    23821 taggtaaacg aggtgatcca caagaaccga accattcgcc ggtcacatca tcgttatccc
    23881 cattgtcatt atctggatct ggttgtttag gtaagacagg ggcgttattc agcttcggtt
    23941 ttaaagagga accgccttgt tgattctcat cgtttgcagt acccggcaat gatgcagtgc
    24001 tctgccatgt ctggcgatct gcatccacca gatgagatgc cacaggttct ggctcaccaa
    24061 ataactttct ctggttacgt gccttaggat ccagctcaag tagccaccga tcatagttaa
    24121 gagaagggtg tggtaaaaca ttcaccaaca taccgataaa ctcatctctg aacatttcga
    24181 aggaatacac ctccggatcg tcaaactgag tacagacatg accgaaaatc tcattaaaat
    24241 cactatcagt ctcagtcatc accgaatatt gctgccaaat ttttaaagca tcagctcgca
    24301 aatttaataa attaactatc tggggcttac ctaacccaga aaccagcaac tccggcataa
    24361 agggataaag atattccacc gtatgttcca tacggctgat cattgagttg tgaatggggt
    24421 atccctgctg tccgagcagg tccgccagct ctcgcagggt taccgttcgt ccaagagttt
    24481 cttcatgaat ggcgcgggct ttttttattc ccagcgcttt gtcgataaag gttagatccc
    24541 cccttacatc attctcggcc agatgcccta ccagacattc aagcctgcca ggccatggct
    24601 tgaacagagc atggaagcgg taaaagcgtt catcctgtgt ttcagcaaac agctctcgca
    24661 gaatggcgta gcgggtgtta ccaccatcgc tgaaaatata aggagagccg gggatatccg
    24721 ggtttttcgt cactttcggg accgtatcca gaccacgggc tctgatggat tccttgattt
    24781 catcgtactt aggattgcgt gttgtgcgag gattgtccgg attaggagct acctcatcga
    24841 gcgtcagcac catcggcatt tcactggtcg gcataatcgc aacagcagcg gttgtagctg
    24901 cagatgattc cttcgccccc tgtagcagcg cattattaag atttaacagt ggtgctttag
    24961 ccatagctca cctccccata accaaggtga tactccgaga agcgcatata ctccccctca
    25021 aagcgaactt tgacagtgcc cagcggcccc tgacgttgct tacccagaat gatttcagct
    25081 atgcctctat ccggggagtg ctcgttataa acttcatcgc ggtacaggaa catgatgaca
    25141 tccgcatcct gctccagtga gccggaatcc cgaaggtcac tgaccatcgg acgtttatcc
    25201 tgacgctgtt caacgctgcg attgagctgg gataaagctg ccacagggca ccttatctct
    25261 ttggccagtg acttgagcga acgggaaatc tcctgaattt cctgagtgcg gttctcccgg
    25321 ccaggacaac tcattaactg aagataatca acaagaataa gtgagggctg accgtattta
    25381 cgcacattac gccgcgcgct gatacgtaac gtggaaggcg tctgataact ggtatcgtct
    25441 atcagcaaac gtccttccca ggaggtcagt tttgctacgg catccgcaag taaactccac
    25501 tgcccttcgc tcagcagacc tttgcgcagg ttatcgaagg gcactctggc cagcattgaa
    25561 agcagacgca ttatcagctg ctgggttggc atctctatgc tgtagaactg aacggtcttg
    25621 ccgggactgc cttccagcgc agcaacggca tgtttcagtg cttctgccgt tttccccatt
    25681 gatggccggg cacccagtaa aatcaggtca ccgtcctgcc agccacaggt tttctcatcc
    25741 agttcagcaa aacctgtcgc tgtaccggtc acaccgcttc ccccactgac cgattccagc
    25801 cagctgaccg tgtcagcgac ctgagtcgtt acgctcagac aaatgtcggg gtcacaggcc
    25861 tgctgagcca gactaaataa ctgcttttcg gccttttcaa tcagaccggg tatatccgca
    25921 tcgccgactg aggccagttg atgtagctca tgccccagct taaccagccg tcgcttacga
    25981 ctgtactcgc gcacaatttc ggcataagca acgatattgg cggcgctggg cgtgtttttt
    26041 gacagttcag ccagataagc gacccccccg caccgctcca gcagatcttt tcgctccatg
    26101 gattcggaca gggttatcag gtcaatgggc aggccagcac tgaccaaccg ttctatctcc
    26161 cgaaaaatga tctgatgctg gccataataa aaatctccgg aattcagaag cggcgcaatt
    26221 tcatcccagc ggtcgttatc gagcatcagt ccgcccagaa caccggtttc agctccgaca
    26281 ttaaacagca tggatactgc agaaacagat ttatggctca tacctcatcc gccccctgac
    26341 caaatccggg ctgaggccgg ttaaccagaa ccgcatcaaa cttatctttc cattgaggaa
    26401 ataactcaca gaccaggtgg tgcatggact ccgctgccgg caggcttacc cggtcagttt
    26461 tatattcgag acgatgtact ggctgcccgc acgcatgccc acgtttgtag acttccagtt
    26521 gctctatttc ggtattcagc attgatatgg caatacggtc tgactggggg tactgacctt
    26581 tatccacgat tgccttgagt tcgttgaggg tgtttcgatc cagtacagtg ggttcaacac
    26641 agttggcgag aattcgaata tcgggaatat ggataccgta gggttccaga accagaagtt
    26701 tggataaaag acgtacagtg ccgcgtagga actcacgtac atcgggtaaa atcggtttaa
    26761 taacacccat gacgctttga gtcgcagcga gcaccacgag ctccaccatc accccgccag
    26821 cgcctttgga atcgacgatt atgacgtcat attgtctgaa aagaggatgc tgcaggacat
    26881 tacgcagacg cattctgcca tcagctgcat gcagcatatc attggaaaga cgatcgtcag
    26941 gatcgttgga aatgatgacg tcaagattgg gaataaccgt gcgggaaatg atgctgtcag
    27001 gtttgttaag gtcagcagtc tgcatgagta attcatacag tccgcagggt gcttcatagt
    27061 gaagtttaaa aatactgctg gctgttggct gattataatc accatcgatt agcagtgttt
    27121 tcagaccagc atcggcggtg taacccgcaa tattgcctgc cttggttgac ttcccttctc
    27181 cgcccttagt ggatactact ggcaatacta ccgggaattg ttgctcatca gggagtaaca
    27241 acgaatgcgg tgaaacctgc tgtgccaaat gaatactggc gtctggtttt ctttctacag
    27301 actccccggt tgaaacctgg ggggaacact taacgcgaga tacagtttgc atgcaataca
    27361 ctcgaaattt attcgaatgt gttcgcctgc ctgctaccaa ttcaaaaagt caaagcggtg
    27421 tctaactttt tgacaagggg attgaaaatc cccgtgtccg tggttcgatt ccgagtccgg
    27481 gcaccactta ttcagaaaat ccagcctatg gctgggtttt tgcttttctg ggaatggaaa
    27541 tccgtagccc ccatctctgg cctgattagc tataacggga aggccagatt ttctctggcg
    27601 caacgcccag cgcttcggcg atcagccgct catctttggg cctgggtcaa aagcttactt
    27661 agctacaggg agattattac cagtaataac gcgtatcact ccatctgacg gttcgctagc
    27721 ctcgacaagt gaatccaata tctccgccat gaac
//
LOCUS       DAJVBX010000032        27338 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.032, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000032 DAJVBX010000000
VERSION     DAJVBX010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 27338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27338
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.032"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            381..836
                     /locus_tag="OPV72_001241"
     CDS             381..836
                     /locus_tag="OPV72_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4385 domain-containing protein"
                     /protein_id="HCR9913597.1"
                     /translation="MAIKPFNYQQDFSSIDFRQQPELYQVGRGEQGGLLVEPYKSEIL
                     PFWRYKDEASAMKSAEQIYQLFEAYRQQDDFVGMDMARKFIQMGYTRARRYANYKGGK
                     KYAEDGSLNTRGNDPIKAAAATVFKGWWDKIRQDEDYLKRKRQHQARWG"
     gene            940..2241
                     /locus_tag="OPV72_001242"
     CDS             940..2241
                     /locus_tag="OPV72_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR9913598.1"
                     /translation="MAEIIQRIDKNNAEAPEMRRHIWAIVGASSGNLVEWFDFYVYSF
                     CSLYFAHIFFPSSNTTTQLLQTAGVFAAGFLMRSIGGWLFGRIADRRGRKASMLISVC
                     MMCMGSLVIACLPGYDTIGTWAPALLLIARLFQGLSVGGEYGTSATYMSEVALEGRKG
                     FFASFQYVTLIGGQLLALLVVVILQQVLEDAELRAWGWRIPFALGAVLAVVALWLRRQ
                     LDETSKHETRALKEAGSLKGLWRNRKAFLMVLGFTAAGSLCFYTFTTYMQKYLVNTAG
                     MHANVASGIMTAALCVFMLVQPLFGALSDKIGRRTSMLCFGALATLFTVPILSALQNV
                     TSPYAAFALVMCALLIVSFYTSISGILKAEMFPAQVRALGVGLSYAVANALFGGSAEY
                     VALSLKSVGMESSFFWYVTAMAVLAFLVSLMLHRKGKGLRL"
     gene            complement(2238..2561)
                     /locus_tag="OPV72_001243"
     CDS             complement(2238..2561)
                     /locus_tag="OPV72_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfiM family lipoprotein"
                     /protein_id="HCR9913599.1"
                     /translation="MRVLIPFTVLFLSGCSHLANDHWSGQDKAQHFMASAMLSAAGNE
                     YARHQGVSPDRSAAIGLMFSLSLGASKELWDSRPEGSGWSWKDFVWDVAGATTGYAIW
                     QMARY"
     gene            complement(2606..3961)
                     /gene="pssA"
                     /locus_tag="OPV72_001244"
     CDS             complement(2606..3961)
                     /gene="pssA"
                     /locus_tag="OPV72_001244"
                     /EC_number="2.7.8.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--serine
                     O-phosphatidyltransferase"
                     /protein_id="HCR9913600.1"
                     /translation="MLSKFKRNKHQQHLAQLPKISQSVDDVDFFYTPATFRETLLEKI
                     ASATQRICIVALYLEQDDGGKGILDALYAAKRQRPELDVRVLVDWHRAQRGRIGAAAS
                     NTNADWYCRLAQENPGIDVPVYGVPINTREALGVLHFKGFIIDDSVLYSGASLNDVYL
                     HQHDKYRYDRYQLIRNRQMADIMFDWVTQNLMNGRGVNRLDNTQRPKSPEIKNDIRLY
                     RQELRDASYHFQGDANDEQLSVTPLVGLGKSSLLNKTIFHLMPCAEHKLTICTPYFNL
                     PAVLVRNIIQLLRDGKKVEIIVGDKTANDFYIPEDEPFKIIGALPYLYEINLRRFLSR
                     LQYYVNTDQLVVRLWKDDDNTYHLKGMWVDDKWMLLTGNNLNPRAWRLDLENAILIHD
                     PKQELAPQREKELELIRTHTTIVKHYRDLQSIADYPIKVRKLIRRLRRIRIDRLISRI
                     L"
     gene            complement(4076..6736)
                     /gene="pat"
                     /locus_tag="OPV72_001245"
     CDS             complement(4076..6736)
                     /gene="pat"
                     /locus_tag="OPV72_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein lysine acetyltransferase"
                     /protein_id="HCR9913601.1"
                     /translation="MSQQGLEALLRPKSIAVIGASMKPHRAGYLMMRNLLAGGFNGPV
                     LPVTPAWKAVLGVMAWPDIASLPFTPDLAILCTNASRNLALLDALGAKGCKTCIILSA
                     PTSQHEELLASARHYKMRLLGPNSLGLLAPWQGLNASFSPVPIKQGKLAFISQSAAVS
                     NTILDWAQQREMGFSYFIALGDSLDIDVDELLDYLARDSKTSAILLYLEQLSDARRFV
                     SAARSASRNKPILVIKSGRSPAAQRLLNTSAGMDPAWDAAIQRAGLLRVQDTHELFSA
                     VETLSHMRPLHGDRLMIISNGAAPAALALDELWSRNGKLATLSEETCLQLRQTLPAHI
                     DIANPLDLCDDASSEHYVKTLDILLASQDFDALMVIHSPSAAAPGTESAHALIETIKR
                     HPRGKFVTLLTNWCGEFSSQEARRLFSEAGLPTYRTPEGTITAFMHMVEYRRNQKQLR
                     ETPALPSNLTSNTAEAHNLLQRAIAEGATSLDTHEVQPILHAYGLHTLPTWIASDSAE
                     AVHIAEQIGYPVALKLRSPDIPHKSEVQGVMLYLRTASEVQQAANAIFDRVKMAWPQA
                     RIHGLLVQSMANRAGAQELRVVVEHDPVFGPLIMLGEGGVEWRPEEQAVVALPPLNMN
                     LARYLVIQGIKQRKIRARSALRPLDIVGLSQLLVQVSNLIVDCPEIQRLDIHPLLASA
                     SEFTALDVTLDIAPFDGDNESRLAVRPYPHQLEEWVEMKNGDRCLFRPILPEDEPQLR
                     QFIAQVTKEDLYYRYFSEINEFTHEDLANMTQIDYDREMAFVAVRRMDNAEEILGVTR
                     AISDPDNVDAEFAVLVRSDLKGLGLGRRLMEKLIAYTRDHGLKRLNGITMPNNRGMVA
                     LARKLGFQVDIQLDEGIVGLTLNLAKCDES"
     gene            complement(6790..7470)
                     /gene="tapT"
                     /locus_tag="OPV72_001246"
                     /gene_synonym="tuaA"
                     /gene_synonym="yfiP"
     CDS             complement(6790..7470)
                     /gene="tapT"
                     /locus_tag="OPV72_001246"
                     /gene_synonym="tuaA"
                     /gene_synonym="yfiP"
                     /EC_number="2.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-uridine aminocarboxypropyltransferase"
                     /protein_id="HCR9913602.1"
                     /translation="MTNNAVLQLRAERLARATRPFLARGNRVRRCQRCLLPLKSCLCD
                     TLTPSQAKSRFCLVMFDTEPMKPSNTGRLIADILPDTAAFQWSRTEPPQALLELVQHP
                     DYQPIVVFPASYAGEAREVISTPPAGKPPLFIMLDGTWPEARKMFRKSPYLDHLPVIS
                     VDLSRLSAYRLREIHAEGQYCTAEVAIALLDLAGDPEAATSLGEHFIRFKTRYLAGKT
                     QHPGNVTA"
     gene            complement(7543..7962)
                     /gene="trxC"
                     /locus_tag="OPV72_001247"
     CDS             complement(7543..7962)
                     /gene="trxC"
                     /locus_tag="OPV72_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin TrxC"
                     /protein_id="HCR9913603.1"
                     /translation="MNTVCTHCQAINRIPGDRLQDAAKCGRCGHELFDGEVINATGET
                     LDKLLKDDLPVVIDFWAPWCGPCRNFAPIFEDVAEERSGKVRFVKVNTEAERELSARF
                     GIRSIPMIMIFKHGQVVDMLNGAVPKAPFDSWLNEAL"
     gene            8166..9203
                     /locus_tag="OPV72_001248"
     CDS             8166..9203
                     /locus_tag="OPV72_001248"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA/rRNA methyltransferase"
                     /protein_id="HCR9913604.1"
                     /translation="MNDELKNKSGKVKVMYVRSDDDSDKRTHNPRTGKGGGRPAKSRT
                     DGGRRPARDERNNQSRDRKHETSPWRTVSRAPGDETPEKVDHGGISGKSFIDPEVLRR
                     QRAEETRVYGENACQALFQSRPDAIVRAWFIQSVTPRFKEALRWMAANRKAYHVVDEA
                     ELAKASGTEHHGGVCFLIKKRNGTTVKQWVKQAADQDCVLALEDVANPHNLGGMMRSC
                     AHFGVKGVVVQDAALLESGAAIRTAEGGAEHVQPITGESIVDVLDDFRQAGYTVVTTS
                     SDRGQALFSTTLPEKMVLVLGREYDYLPEAAREPDDLCVKINGTGNVESLNVSVATGV
                     LLAEWWRQNKA"
     gene            complement(9319..10008)
                     /gene="ung"
                     /locus_tag="OPV72_001249"
     CDS             complement(9319..10008)
                     /gene="ung"
                     /locus_tag="OPV72_001249"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HCR9913605.1"
                     /translation="MATELTWHDVLADEKQQPYFINTLHTVAGERQSGITVYPPQKDV
                     FNAFRFTELGDVKVVILGQDPYHGPGQAHGLAFSVRPGIAPPPSLVNMYKELEASIPG
                     FVRPAHGYLESWARQGVLLLNTVLTVRAGQAHSHASLGWETFTDKVISLINQHREGVV
                     FLLWGSHAQKKGAIIDPQRHHILKAPHPSPLSAHRGFFGCNHFALTNQWLEQHGEKTI
                     DWTPVLPAESE"
     gene            10327..10710
                     /gene="grcA"
                     /locus_tag="OPV72_001250"
     CDS             10327..10710
                     /gene="grcA"
                     /locus_tag="OPV72_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007728348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autonomous glycyl radical cofactor GrcA"
                     /protein_id="HCR9913606.1"
                     /translation="MITGIQITKAANDDLLNSFWLLDSEKGEARCIVAKSGFAEDEVV
                     AVSKLGEIEYREIPMEVKPEVRVEGGQHLNVNVLRRETLEDAVKHPEKYPQLTIRVSG
                     YAVRFNSLTPEQQRDVIARTFTESL"
     gene            complement(10772..11359)
                     /gene="eamB"
                     /locus_tag="OPV72_001251"
     CDS             complement(10772..11359)
                     /gene="eamB"
                     /locus_tag="OPV72_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine/O-acetylserine transporter"
                     /protein_id="HCR9913607.1"
                     /translation="MTPMLLSAFWTYTLITALTPGPNNILALSAATAHGFRQSIRVLA
                     GMSLGFLVVMLLCAGIAFSLAVIDPAIIHLLSWVGAAYILWLAWKIATSPAADEKVRP
                     KPVGFWVSFGLQFVNVKIILYGITALSTFVLPQTQALNWVIGVSILLALIGTFGNVCW
                     ALAGHLFQRAFRHYGRQLNIILALLLVYCAVRIFY"
     gene            11462..12330
                     /locus_tag="OPV72_001252"
                     /pseudo
     CDS             11462..12330
                     /locus_tag="OPV72_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311470.2"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            complement(12377..13711)
                     /gene="srmB"
                     /locus_tag="OPV72_001253"
     CDS             complement(12377..13711)
                     /gene="srmB"
                     /locus_tag="OPV72_001253"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase SrmB"
                     /protein_id="HCR9913608.1"
                     /translation="MTVTTFSELELDESLLDALQDKGFTRPTAIQAAAIPPALDGRDV
                     LGSAPTGTGKTAAYLLPALQHLLDFPRKKSGPPRILILTPTRELAMQVADHARELAKH
                     THLDIATITGGVAYMNHAEVFSENQDIVVATTGRLLQYIKEENFDCRAVETLILDEAD
                     RMLDMGFAQDIEHIAGETRWRKQTMLFSATLEGDAIKDFAERLLEDPVEVSANPSTRE
                     RKKIHQWYYRADNFEHKVALLKHLLKQDDATRSIVFVRKRERVHELAETLRLAGINNC
                     YLEGEMAQIKRNEGIKRLTDGRVNVLVATDVAARGIDIPDVSHVINFDMPRSGDTYLH
                     RIGRTGRAGRKGTAISLVEAHDHLLLLKIGRYIEEPLKARVIDELRPTTRAPSEKLTG
                     KPSKKVLAKRAEKKKEKEKEKPRVKKRYRDTKNIGKRRKPSGTKMQEQSSEE"
     gene            13841..14578
                     /gene="trmN"
                     /locus_tag="OPV72_001254"
     CDS             13841..14578
                     /gene="trmN"
                     /locus_tag="OPV72_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA(1)(Val)
                     (adenine(37)-N(6))-methyltransferase TrmN"
                     /protein_id="HCR9913609.1"
                     /translation="MSQSGSVLRRNGFTFKQFFVAHDRCAMKVGTDGILLGAWAPVAD
                     VKRILDIGTGSGLLALMLAQRTDDSVPVDAVELDAGAAMQAQENVAHSPWPHRITVHT
                     DDIQRWAPRQTVRFDLIISNPPYYEPGVECSTPQREQARYTATLDHQTLLAIAADCIT
                     EDGFFCVVLPEQIGNAFTQQALNMGWHLRLRTDVAENEARLPHRVLLAFSPQAGECFS
                     DRLVIRGSDQNYSESYTALTQAFYLFM"
     gene            complement(14563..16185)
                     /gene="nadB"
                     /locus_tag="OPV72_001255"
     CDS             complement(14563..16185)
                     /gene="nadB"
                     /locus_tag="OPV72_001255"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HCR9913610.1"
                     /translation="MMTTPELSCDVLIIGSGAAGLSLALRLAEKHKVIVLSKGPVSEG
                     STFYAQGGIAAVFDETDSIASHVEDTLIAGAGICDRHAVEFVASNARTCVQWLIDQGV
                     LFDTHVQPNGKESYHLTREGGHSHRRILHAADATGKEVETTLVSRAQNHPNIQVLERS
                     NAVDLIISDKIGLPGPRRVVGAWIWNRNKEWVETCHAKSVVLATGGASKVYQYTTNPD
                     ISSGDGIAMAWRAGCRVANLEFNQFHPTALYHPQARNFLLTEALRGEGAYLKRPDGSR
                     FMPDVDERGELAPRDIVARAIDHEMKRLGADCMFLDISHKPDDFVRQHFPMIYAKLLD
                     LGMDLTKEPIPIVPAAHYTCGGVVVDDYGRTDVDGLYAIGEVSYTGLHGANRMASNSL
                     LECLVYGWSAAMDIDRRMPSVHSVDVLPAWDESRVENADERVVIQHNWHELRLLMWDY
                     VGIVRTTKRLERALRRITMLQQEIDEYYANFRVSNNLLELRNLVQVAELIVRCAMMRK
                     ESRGLHFTLDYPQQLAESGPSILSPLTPHINR"
     gene            16449..16613
                     /gene="rseD"
                     /locus_tag="OPV72_001256"
     CDS             16449..16613
                     /gene="rseD"
                     /locus_tag="OPV72_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rpoE leader peptide RseD"
                     /protein_id="HCR9913611.1"
                     /translation="MEDKTCLQHDKQKQMRNGTLRNIDTLTCCLLIVRLMEWRFESAW
                     KFGLGRHYLG"
     gene            16610..17185
                     /gene="rpoE"
                     /locus_tag="OPV72_001257"
     CDS             16610..17185
                     /gene="rpoE"
                     /locus_tag="OPV72_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005070454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoE"
                     /protein_id="HCR9913612.1"
                     /translation="MSEQLTDQVLVERVQKGDQKAFNLLVVRYQHKVASLVSRYVPSG
                     DVPDVVQESFIKAYRALDSFRGDSAFYTWLYRIAVNTAKNYLVAQGRRPPSSDVDAIE
                     AENFESGGALKEISNPENLMLSEELRQIVFRTIESLPEDLRMAITLRELDGLSYEEIA
                     AIMDCPVGTVRSRIFRAREAIDNKVQPLIRR"
     gene            17217..17867
                     /gene="rseA"
                     /locus_tag="OPV72_001258"
     CDS             17217..17867
                     /gene="rseA"
                     /locus_tag="OPV72_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma-E factor RseA"
                     /protein_id="HCR9913613.1"
                     /translation="MQKEKLSALMDGETLDSELLKALTHDSEMQKTWESYHLIRDSMR
                     GDTPDVLHFDISARVMAAIENEPVRQVTPLIPEAQPAPQQWQKMPFWKKVRPWAAQLT
                     QMGVAACVSLAVIVGVQHYNGQSETSQQPETPVFNTLPMMGKASPVSLGVPSEAAPVG
                     SQQQQVQEQRRRINAMLQDYELQRRLHSEQLQFEQAQTQQAAVQVPGIQTLGTQSQ"
     gene            17867..18823
                     /gene="rseB"
                     /locus_tag="OPV72_001259"
     CDS             17867..18823
                     /gene="rseB"
                     /locus_tag="OPV72_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-E factor regulatory protein RseB"
                     /protein_id="HCR9913614.1"
                     /translation="MKQLWFAMSLVAASLFFSVNASADPASGALLQQMNIASQSLNYE
                     LSFVSITKQGVESLRYRHARLDSRPLAQLLQLDGPRREVVQRGNEISYFEPGLEPFTL
                     NGDYIVDSLPSLIYTDFKRLAPYYDFISVGRTRIADRLCEVIRVVARDGTRYSYIVWM
                     DMDTKLPMRVDLLDRDGETLEQFRVIAFTVSQDIGSTMQALAKANLPPLLSVPGGEKT
                     KFNWNPSWVPQGFSEVSSSRRPLPTMDNLPIESRLYSDGLFSFSVNVNRATQNSSDQM
                     LRTGRRTVYSSVRDNAEITIVGELPPQTAKRIADSIKFRAVQ"
     gene            18820..19299
                     /gene="rseC"
                     /locus_tag="OPV72_001260"
     CDS             18820..19299
                     /gene="rseC"
                     /locus_tag="OPV72_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SoxR-reducing system protein RseC"
                     /protein_id="HCR9913615.1"
                     /translation="MIKEWATVISWQNGQAVVSCDVKASCSSCASRAGCGSRVLNKLG
                     PQTTHTIVVPSAEPLAPGQKVELGIAEKSLLGSALLVYMSPLAGLFLCAALFQMLFGS
                     DLAALSGAVLGGVGGFLVARGYSRKLAERDAWQPVILNVALPPDLVRVETTSIETRQ"
     gene            19558..21357
                     /gene="lepA"
                     /locus_tag="OPV72_001261"
     CDS             19558..21357
                     /gene="lepA"
                     /locus_tag="OPV72_001261"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HCR9913616.1"
                     /translation="MKNIRNFSIIAHIDHGKSTLSDRIIQICGGLSDREMEAQVLDSM
                     DLERERGITIKAQSVTLDFKASDGETYQLNFIDTPGHVDFSYEVSRSLAACEGALLVV
                     DAGQGVEAQTLANCYTAMEMDLEVVPVLNKIDLPAADPERVAEEIEDIVGIDATDAVR
                     CSAKTGVGVTDVLERLVRDIPPPQGDPDGPLQALIIDSWFDNYLGVVSLVRIKNGTMR
                     KGDKIKVMSTGQTYNADRLGIFTPKQVDRTELKCGEVGWLVCAIKDILGAPVGDTLTS
                     ARNPAEKALPGFKKVKPQVYAGLFPVSSDDYESFRDALGKLSLNDASLFYEPESSSAL
                     GFGFRCGFLGLLHMEIIQERLEREYDLDLITTAPTVVYEVETTAKETIYVDSPSKLPP
                     LNNIYELREPIAECHMLLPQAYLGNVITLCIEKRGVQTNMVYHGNQVALTYEIPMAEV
                     VLDFFDRLKSTSRGYASLDYNFKRFQASDMVRVDVLINNERVDALALITHRDNSQSRG
                     RELVEKMKDLIPRQQFDIAIQAAIGTHIIARSTVKQLRKNVLAKCYGGDISRKKKLLQ
                     KQKEGKKRMKQIGNVELPQEAFLAILHVGKDNK"
     gene            21374..22348
                     /gene="lepB"
                     /locus_tag="OPV72_001262"
     CDS             21374..22348
                     /gene="lepB"
                     /locus_tag="OPV72_001262"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HCR9913617.1"
                     /translation="MANMFALILVIATLVTGILWCVDKFVFAPKRRARQAAAQTASGD
                     ALDNATLNKVAPKPGWLETGASVFPVLAIVLIVRSFLYEPFQIPSGSMMPTLLIGDFI
                     LVEKFAYGIKDPIYQKTLIETGHPKRGDIVVFKYPEDPKLDYIKRAVGLPGDKITYDP
                     VAKEVTIQPGCSSGQACENALPVTYSNVEPSDFVQTFARRNGGEATSGFFEVPLNETK
                     ENGIRLTERKETLGDVTHRILMVPIAQDQLGMYYQQPGQPLATWVVPPGQYFMMGDNR
                     DNSADSRYWGFVPEANLVGKAVAIWMSFDKQEGEWPTGVRLSRIGGIH"
     gene            22622..23302
                     /gene="rnc"
                     /locus_tag="OPV72_001263"
     CDS             22622..23302
                     /gene="rnc"
                     /locus_tag="OPV72_001263"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004248457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HCR9913618.1"
                     /translation="MNPIVINRLQRKLGYTFNHQELLQQALTHRSASSKHNERLEFLG
                     DSILSFVIANALYHRFPRVDEGDMSRMRATLVRGNTLAELAREFDLGECLRLGPGELK
                     SGGFRRESILADTVEALIGGVFLDSNIQTVEQLILNWYKTRLDEISPGDKQKDPKTRL
                     QEYLQGRHLPLPSYLVVQVRGEAHDQEFTIHCQVSGLSEPVVGTGSSRRKAEQAAAEQ
                     ALKKLELE"
     gene            23299..24204
                     /gene="era"
                     /locus_tag="OPV72_001264"
     CDS             23299..24204
                     /gene="era"
                     /locus_tag="OPV72_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HCR9913619.1"
                     /translation="MSTDKTYCGFIAIVGRPNVGKSTLLNKLLGQKISITSRKAQTTR
                     HRIVGIHTEGPYQAIYVDTPGLHMEEKRAINRLMNKAASSSIGDVELVIFVVEGTRWT
                     PDDEMVLNKLRDGKAPVILAVNKVDNVQEKADLLPHLQFLASQMNFLDIVPISAETGM
                     NVDTIASIVRKHLPEAIHHFPEDYITDRSQRFMASEIIREKLMRFLGAELPYSVTVEI
                     ERFVTNERGGYDINGLILVEREGQKKMVIGNKGAKIKTIGIEARKDMQEMFEAPVHLE
                     LWVKVKSGWADDERALRSLGYVDDL"
     gene            24216..24944
                     /gene="recO"
                     /locus_tag="OPV72_001265"
     CDS             24216..24944
                     /gene="recO"
                     /locus_tag="OPV72_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HCR9913620.1"
                     /translation="MEGWQRAFVLHSRPWSETSLMLDVFTEESGRVRLVAKGARSKRS
                     NLKGALQPFTPLLLRYSGRGEVKTLRSAEAVSLALPLSGITLYSGLYINELLSRVLEY
                     ETRFSELFFDYLNCIQALAGTTGSPEPALRRFELALLGHLGYGVNFTHCAGSGERVDD
                     TMTYRYREEKGFFASVVIDNNTFTGRHLKALEAREFPDVDTLRAAKRFTRMALKPYLG
                     GKPLKSRELFRQFMPKRTVKTKKD"
     gene            24956..25687
                     /gene="pdxJ"
                     /locus_tag="OPV72_001266"
     CDS             24956..25687
                     /gene="pdxJ"
                     /locus_tag="OPV72_001266"
                     /EC_number="2.6.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxine 5'-phosphate synthase"
                     /protein_id="HCR9913621.1"
                     /translation="MAELLLGVNIDHIATLRNARGTDYPDPVQAAFIAEQAGADGITV
                     HLREDRRHITDRDVRILRQTLHTRMNLEMAVTEEMLAIAVETRPHFCCLVPEKRQEVT
                     TEGGLDVAGQRDKMRDACARLAAAGIQVSLFIDADERQINAAAEVGAPFIEIHTGCYA
                     NAETDAEQAKELARIASAATLAARLGLKVNAGHGLTYHNVKAIAALPEMHELNIGHAI
                     IGRAVMTGLKEAVAEMKRLMLEARG"
     gene            25687..26067
                     /locus_tag="OPV72_001267"
     CDS             25687..26067
                     /locus_tag="OPV72_001267"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HCR9913622.1"
                     /translation="MAILGLGTDIVEIARIEAVISRSGERLARRVLSDNEWAIWETHQ
                     QPVRFLAKRFAVKEAAAKAFGTGIRNGLAFNQFEVFNDELGKPRLRLWGEALTLAEKL
                     GVAHMHVTLADERHYACATVILES"
     gene            complement(26179..26439)
                     /locus_tag="OPV72_001268"
     CDS             complement(26179..26439)
                     /locus_tag="OPV72_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhL family 4Fe-4S dicluster ferredoxin"
                     /protein_id="HCR9913623.1"
                     /translation="MALLITKKCINCDMCEPECPNEAISMGDSIYEINSDKCTECVGH
                     YETPTCQKVCPIPNTILQDPAHVETEEQLWDKFVLMHHADKL"
     gene            complement(26492..>27338)
                     /locus_tag="OPV72_001269"
     CDS             complement(26492..>27338)
                     /locus_tag="OPV72_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCR9913624.1"
                     /translation="SRLFITQPSLSQQIKQLESSLKTILFKRKGRGIKLTKAGIILQR
                     HANKIMLDLKNAENELLPYQDQQRDTISIGVSGSYLVLPAFRNFMAHHPEISLNVKEF
                     STEQTIKKLTDSAVDIGIVYRTALPAQLSSTMLFEDEIIAAIPLSHPLATRERLHLKD
                     LNDQPIIVLNDSLLLRGSITTEFNNRKVVPNVICELDNHYSCLEYAEAQIGIAFITRS
                     LTHLSTPKNVRLVSLGIPAFFIPVMLVHSNDLSLDNATICLLKQIKNFYTVDNKSAPE
                     KSWPE"
BASE COUNT         6421 a         6885 c         7522 g         6510 t
ORIGIN      
        1 tttatctgtg gtctgccggt gagcactctc ctgaggagga caaatccgcc gggagcggat
       61 ttgaacgttg cgcagtaacg gcccgtaggg tggcgggcag cacgcccgcc ataaactgcc
      121 aggcatcaga caagtgaaga agcccgttct gacggacggg cttctttgcg tgtgtggtaa
      181 ctgtaaaaat gtaggcctga taagcgcagc gccatcaggc aacctgcacc gccggatggc
      241 agcttcgcct tatccggcct acagcaatta tcccgcctac gaagctggtg ctcttgtaga
      301 accgataaga gcacaaccca cccaatcgtt aacgatgaac tatcctttac acgtgcttat
      361 ataagcagtg aggattttca ttggctatca aaccttttaa ctaccagcaa gacttttcca
      421 gcattgactt ccgccagcag cctgaattgt atcaggttgg acgaggagag cagggggggc
      481 tactggttga accctacaaa agcgaaattc ttcctttctg gcgctataaa gatgaagcat
      541 cggcgatgaa atccgcagaa cagatctacc agttgttcga agcttaccgg cagcaggatg
      601 atttcgttgg tatggacatg gcgcgtaaat ttattcagat gggatacacc cgcgccaggc
      661 gatacgctaa ctataaaggt ggtaaaaagt atgcagaaga cggcagcctg aatacacggg
      721 gtaatgatcc tattaaggcc gcggcggcaa cggttttcaa aggttggtgg gataaaatcc
      781 gtcaggacga agactatctg aaacggaaac gccagcatca ggcacggtgg ggataaaaat
      841 tagcagacaa ataattaaca ctttatttac tttttagtct cgcgtaatct gaatctccaa
      901 aataaaaggc cgattaagcc tggcaacaag gagaacagta tggcagaaat tattcagcgt
      961 atagataaaa acaacgctga ggctccggag atgcggcgac acatatgggc tatcgtgggg
     1021 gcctcttccg gaaacttagt ggaatggttt gatttctacg tctactcttt ctgctcgctc
     1081 tattttgcac atatcttctt tccttctagt aataccacta ctcagctttt gcaaacggca
     1141 ggcgtctttg ccgccggttt tttaatgcgg tctatcggtg gttggctgtt tggacgcatt
     1201 gccgatcgac gcgggcgcaa agcctcaatg ttgatttcgg tgtgcatgat gtgcatgggg
     1261 tcgctggtga ttgcctgctt acctggttac gataccatcg gcacctgggc accggcgctg
     1321 ctacttattg caaggttatt tcaggggctc tcggtagggg gagagtatgg gaccagcgcg
     1381 acatatatga gtgaagttgc gcttgaaggt cgtaagggat ttttcgcgtc gtttcagtac
     1441 gttacgctta tcggtggcca actactggca ttgctggtcg ttgtgatttt gcagcaggtt
     1501 ctggaggatg ctgagcttcg tgcctgggga tggcgtattc cctttgcgct gggcgccgtg
     1561 ctggcggttg tggcgttatg gctacgtcgc cagctggatg aaacctcgaa gcatgagact
     1621 cgcgcattaa aagaagccgg ttcgttgaaa ggtttgtggc gtaatcgcaa agcctttttg
     1681 atggtgcttg gtttcaccgc ggcaggctcg ctgtgctttt ataccttcac cacctatatg
     1741 cagaaatatc tggtaaatac agcaggtatg catgccaatg tcgccagcgg cattatgacg
     1801 gctgcgctgt gtgttttcat gttggtgcag ccgttattcg gcgcgttatc cgataagatt
     1861 ggcaggcgca cctctatgct atgttttggc gcactcgcga cgcttttcac cgttccaatt
     1921 ctctccgcgt tgcagaatgt gacgtcgcct tatgccgcat ttgctttagt gatgtgcgcg
     1981 ctattgattg tgagtttcta tacctcgatt agcgggatcc tgaaagcgga gatgtttccg
     2041 gcgcaggttc gcgccctggg cgtcggttta tcttacgcgg tagcaaacgc gttatttggc
     2101 ggctctgcgg aatatgtcgc gctgtcgcta aaatctgtcg gtatggagag ttcgttcttc
     2161 tggtatgtta ccgcgatggc cgttctggct ttcctggttt cgttgatgtt gcaccgtaaa
     2221 ggaaagggct tacgccttta gtatcgcgcc atttgccaga tagcgtaacc ggttgtcgcg
     2281 ccagcgacat cccagacaaa atctttccag ctccagccgc tgccttccgg gcggctgtcc
     2341 cagagttctt ttgaggctcc gagactcaaa gaaaacatca gccctatcgc tgcgctgcgg
     2401 tcagggctta ctccctggtg acgcgcatac tcattaccgg ctgccgatag catcgctgat
     2461 gccataaaat gctgggcttt atcctgaccg ctccagtggt cgttagccag atggctgcac
     2521 ccggagagaa acaacaccgt aaaaggaatc aacacgcgca ccagttcact cctaagagaa
     2581 aaccccgtac aggacggggc ttcgattaca ggatacggct aattaatctg tcgatgcgga
     2641 tccggcgcag acggcgaatc aatttacgca cttttatcgg atagtcggca atgctctgca
     2701 ggtcacgata atgttttacg atggttgtgt gcgttcggat aagttccagc tctttttccc
     2761 gctgaggggc aagctcttgc ttaggatcgt ggatcagaat ggcgttttcc agatccagac
     2821 gccaggcgcg aggattcaga ttgttgccgg tgagtagcat ccatttatca tctacccaca
     2881 tccctttcaa atgataggta ttgtcgtcat ctttccacag acgcaccaca agctgatcgg
     2941 tattgacgta atactgtaaa cggctcagga agcggcgcag gttaatctca tagagatagg
     3001 gcagcgcgcc aatgatcttg aacggttcat cttccggaat gtaaaaatca ttcgcggttt
     3061 tatcgccaac aatgatttcg actttctttc cgtcgcgcag tagctgaata atattccgca
     3121 ccagtaccgc tggtagattg aagtaagggg tacaaatggt gagcttatgc tccgcacagg
     3181 gcatgagatg gaaaatggtt ttgttcagca gactggattt tccaagcccg accagcggcg
     3241 taacggagag ctgctcgtca ttagcgtcac cctgaaaatg atatgacgca tcacgcagct
     3301 cctgacggta taagcggata tcgtttttaa tctccgggct tttcggccgc tgggtattat
     3361 ccagacgatt cacaccacgg ccattcatca gattttgcgt cacccagtca aacatgatgt
     3421 ctgccatttg ccgattgcga atcagctggt agcgatcgta gcgatatttg tcatgctgat
     3481 ggagatagac atcgttcagg ctggcgccgc tgtacaggac gctatcatca atgataaagc
     3541 ctttaaaatg cagtacgcca agcgcttctc gcgtattaat cggcacgccg taaaccggga
     3601 catcaatgcc ggggttttcc tgcgccagtc ggcaatacca gtctgcattg gtattcgagg
     3661 ccgctgcgcc aatgcgcccg cgttgcgcgc gatgccagtc gaccagcacc ctcacgtcca
     3721 gttcaggacg ctgccgttta gccgcataga gcgcgtcgag tataccttta cccccatcgt
     3781 cctgttccag atacagggca acgatacaaa tacgctgcgt cgcgctggcg attttctcca
     3841 gcagtgtctc ccgaaaagta gcaggagtat aaaagaaatc tacatcatca actgactgag
     3901 aaatcttagg gagttgggca aggtgttgtt gatgtttatt acgcttaaat tttgacaaca
     3961 tcacagtgca tttcttctct gttcattgaa gggtcctctg tgctatgcag acgacataag
     4021 cgagcaataa taacatcagt acccgttaaa gtggtcaaca tttccagtac attactcacg
     4081 attcatcaca tttggccaga ttcagcgtca atcccacgat gccctcgtcg agctgaatat
     4141 cgacctgaaa tcccagtttt ctggccagcg cgaccatgcc gcgattgttc ggcatcgtaa
     4201 taccgttcag ccgcttcaat ccgtgatcgc gagtataggc aatcaatttc tccattaaac
     4261 ggcgtcctaa acccaaccct ttaagatctg aacgcaccaa tacggcaaat tcggcatcta
     4321 cgttgtcagg atcggagatc gcgcgcgtta cgccgaggat ctcttcagcg ttgtccatcc
     4381 gcctcacggc cacaaaggcc atttctcgat cgtagtcgat ctgcgtcatg ttggctaaat
     4441 cttcatgggt gaattcgttg atctcgctga aataacggta gtaaagatcc tctttggtga
     4501 cctgtgcgat gaattgtcgc agttggggct catcttccgg caggatcgga cggaacaggc
     4561 agcgatcgcc gtttttcatc tccacccact cttcaagctg gtggggatag gggcgtaccg
     4621 caagacgact ttcgttatcg ccatcaaacg gggcaatatc cagcgtcaca tccagcgcgg
     4681 taaactcact ggcggaagcc agcagcggat ggatatccag acgctgaatt tccgggcaat
     4741 cgacaatcag gtttgaaacc tggaccagca attggcttaa accgacaata tccagcggac
     4801 gcagcgcgct acgggcgcga attttccgct gtttaatgcc ctgaatcacc agatagcgcg
     4861 ccagattcat gttgagcggc ggcagcgcga cgacggcctg ctcttccgga cgccactcta
     4921 cgccgccttc acccaacata atcaaaggac caaacaccgg atcgtgctcg accaccacac
     4981 gcagctcctg cgcgccggcg cggttagcca tgctttgtac cagcaaaccg tgaatccgcg
     5041 cctgcggcca ggccatcttt acacgatcga aaatggcgtt cgcggcctgt tgtacctcgc
     5101 ttgcggtgcg caggtaaagc atgaccccct gaacttcaga tttatgcgga atgtcgggcg
     5161 agcgcagctt gagagctacc ggatagccta tctgttcggc gatatgcact gcttcagcgc
     5221 tgtcgctggc aatccaggtt gggagcgtgt gcagcccata ggcgtgtaaa atcggctgta
     5281 cttcatgggt atccagtgaa gtggcgcctt ccgcaatcgc ccgctgtaac agattatgcg
     5341 cctcagcggt attggacgtc aggttactcg gcaacgctgg cgtttcccgc agttgcttct
     5401 ggttacgccg gtattccacc atgtgcataa acgcggtaat cgtgccttcc ggcgtgcggt
     5461 aggttggtaa tccggcttcg ctgaacagcc gtcttgcttc ctgagatgag aactcgccgc
     5521 accagtttgt cagcagcgta acaaacttgc ctctggggtg gcgcttaatc gtctcgatca
     5581 gagcatgggc gctttccgta cccggcgcgg cagcgctggg agagtggata accataagcg
     5641 cgtcaaaatc ctgactggcg agcaggatat ccagcgtttt gacgtaatgt tcgctgctgg
     5701 cgtcatcaca cagatccagc ggattggcaa tatcaatgtg cgcgggaagc gtctgccgta
     5761 gttgcaggca ggtctcttcg ctcaatgtcg ccagcttgcc gttacgcgac cacaactcat
     5821 ctaacgccag cgcggcaggc gcggcgccat tgctgatgat catcagtctg tcgccgtgta
     5881 gcggacgcat atggctaagt gtttcgacgg cggaaaaaag ctcgtgcgta tcctggactc
     5941 gcagcaggcc tgcgcgctgg atggccgcat cccacgcagg gtccattccc gcgctggtat
     6001 taagtaaacg ctgggctgcc gggcttcggc cgcttttaat caccagaatc ggtttgttac
     6061 gtgaagcgct acgggcggcg gaaacaaaac ggcgggcgtc gcttaactgt tccagataga
     6121 gcaaaattgc gctggtcttg ctatcgcgcg ccagatagtc cagtagttca tcgacatcaa
     6181 tatccaggct atcgcccagc gcgataaagt aggaaaagcc catttcacgc tgttgcgccc
     6241 agtcaagaat agtattggac acggcggcag actgggaaat aaaagcgagc ttgccctgtt
     6301 taatcgggac gggagaaaag ctggcattca gcccttgcca cggcgcgagg agcccaagac
     6361 tgtttggacc cagcagacgc attttataat gccgggcact ggcaagaagt tcttcatgtt
     6421 gcgacgtggg agcagaaagg ataatgcacg ttttacaacc tttcgcgcca agcgcgtcca
     6481 gtaacgccag gttacggctg gcgttagtgc ataaaatagc cagatcgggg gtgaaaggaa
     6541 gactggcgat atccggccag gccatgacgc ctaaaacggc tttccaggcg ggcgtcacgg
     6601 gaaggacggg gccattgaat ccgcccgcca acaagttacg catcatcagg taacccgcgc
     6661 ggtggggctt cattgatgcg ccaatcaccg cgatcgattt tggtcgcagt agcgcttcca
     6721 gtccttgctg gctcataccg gtttccctta cacagaagtg accggataat tttaaacgct
     6781 ttcgctattt tatgctgtga cgtttcccgg atgttgcgtt tttcctgcca gatagcgcgt
     6841 tttgaaacgg atgaaatgtt cacctaaact ggttgccgcc tcgggatctc ccgccagatc
     6901 taacaacgct atcgcgactt cggcggtaca atattgccct tcggcatgga tttcacgcag
     6961 acgataagct gaaagacgcg ataaatcgac ggaaatgacc ggcagatgat ccagataagg
     7021 gcttttacga aacattttac gtgcttcggg ccaggtgccg tccagcataa taaacagcgg
     7081 cggtttcccg gcgggcgggg tggaaatgac ctcgcgcgct tcgccggcgt aggacgcagg
     7141 aaagaccact atcggctgat aatccggatg ctgtaccagc tccagcaacg cctgcggcgg
     7201 ctcggtacgc gaccactgaa acgccgcggt atctggcaaa atatcggcta tcagccggcc
     7261 ggtattgctg ggtttcatcg gttcagtgtc aaacatgacc agacaaaaac ggcttttcgc
     7321 ctgagaaggc gttaacgtat cacacaggca agattttagc ggcagcaggc agcgttgaca
     7381 gcggcgaacc cgattgcctc tggcaagaaa agggcgagta gcgcgcgcaa gccgttcggc
     7441 gcgtaactga aggacagcgt tattggtcat agaaagcgtt tgcggagaaa aacgctattg
     7501 tggcagaggt gaaaacgggg cacaagatgc gccccgtggc gtttacagcg cttcgttcag
     7561 ccagctgtcg aaaggcgctt taggcactgc gccattaagc atatcgacca cctgtccatg
     7621 tttaaaaatc ataatcatcg ggatgctgcg gataccgaaa cgagcgctga gttcccgttc
     7681 cgcctcggta tttactttga cgaaacggac tttaccgctg cgctcttctg cgacatcctc
     7741 gaagattggc gcaaagttac ggcaagggcc gcaccagggt gcccaaaagt cgatcaccac
     7801 tggaagatcg tccttcaaca gtttgtccag cgtttcgccg gtcgcattaa tgacttctcc
     7861 gtcaaacaac tcatgaccgc agcgtccaca ttttgccgcg tcctgaagcc gatcgccggg
     7921 gatgcggtta atggcctgac aatgggtaca aacggtgttc atagctaacc tctgaatacg
     7981 tcggaagacg tcccgctacg cgcgggatgt ttctataatg ttatatatta tcgaggagtc
     8041 tgtgctaaac aacaatgtgt tttattcaat gagtacaata gtcgcaagct tttaaacgaa
     8101 atcatggcta accggatgca catcgggtaa tcttcgcgct tcgcgcagcg ctggtggaga
     8161 aaagcatgaa cgatgaatta aaaaacaaaa gcggcaaagt caaagtgatg tatgtccgta
     8221 gtgatgatga ctctgataaa cgcacccata acccgcgtac cgggaaaggg ggaggccgcc
     8281 cagcaaagtc tcgcactgac ggtggacgtc gccccgcccg tgatgagcga aataatcaga
     8341 gccgtgaccg taaacatgaa acttcgccgt ggcgcaccgt gtcccgcgcg ccaggcgatg
     8401 aaacgcctga gaaagtcgat catggtggta ttagcggtaa aagttttatc gaccctgaag
     8461 ttttgcgtcg ccagcgtgcg gaagagacgc gcgtctacgg cgaaaatgcc tgccaggcgc
     8521 tattccagag ccgtcctgac gccatcgtgc gcgcatggtt tatccaaagc gtaacgccgc
     8581 gttttaaaga ggcgctgcgc tggatggcgg cgaatcgtaa agcctaccat gtggtggatg
     8641 aagccgaact ggcaaaagct tccgggactg agcaccacgg cggcgtgtgt ttcctgatta
     8701 aaaagcgtaa cggtacgacc gttaagcaat gggtaaagca ggcggcggat caagactgcg
     8761 tgctggcgtt ggaagatgtc gctaacccgc ataatctggg cggcatgatg cgtagctgcg
     8821 cgcacttcgg cgtgaagggc gtggtggtac aggatgcagc gttgctggag tccggcgcgg
     8881 cgattcgtac cgcggaaggc ggggcggaac atgtccagcc aatcactggt gaaagcattg
     8941 ttgacgtact ggatgacttt cgtcaggcgg ggtacaccgt ggtgacgacg tccagcgatc
     9001 gcggtcaggc gctctttagt acgaccctgc cggaaaagat ggtgctggtc ttaggccgtg
     9061 aatatgacta cctgccggaa gcggcgcgcg aacccgacga tctgtgcgtg aaaattaacg
     9121 gcaccgggaa cgtggaaagc ctgaatgtgt cggttgcgac aggcgtactg ctcgccgagt
     9181 ggtggcgaca gaataaagcg taagggctgc agcccggtga cgcaacgcgc gccgggccaa
     9241 tgatgtactt tctaccgccc ggtcagacaa ggcgctttcg cgccgttatc cgggcgataa
     9301 aacggcgagt cgccaacgtt attcactctc agccggtaat actggcgtcc agtcgatagt
     9361 tttctcgccg tgttgttcca gccattggtt cgttagcgca aaatggttac agccaaaaaa
     9421 tccgcggtgc gcagagagtg gcgagggatg cggagctttc agaatatggt ggcgctgtgg
     9481 atcaataatc gcgcctttct tctgggcgtg cgagccccac agcaggaaga cgaccccttc
     9541 gcggtgttgg ttaatcaggc ttatcacttt atccgtaaag gtttcccacc ccaggctggc
     9601 atgagagtgc gcctggcctg cccgtaccgt gagcaccgta ttcagtaaca gtacgccctg
     9661 gcgcgcccag ctttccagat aaccgtgcgc ggggcgaaca aagccgggaa tggaggcttc
     9721 cagctctttg tacatattca ctaatgacgg cgggggagcg atcccaggac gcacggaaaa
     9781 cgccagacca tgtgcctggc cggggccgtg gtaaggatct tgtcccagga tcaccacctt
     9841 aacgtcgccc agttccgtga agcgaaaggc gttaaataca tctttttgcg gcgggtagac
     9901 cgtgataccc gactgacgct cgccagcaac agtgtgaagc gtattgataa agtaaggttg
     9961 ctgtttctca tcagccagca catcgtgcca ggttaactca gtcgccatct cgctctcctg
    10021 cgaatttcca gttcccttag cttaactgct tctttctgca gtgcaaaatc ctgcgtgcta
    10081 caaaaacggt tacctacaaa agatagttga aaatttatgt aaaaagttta taggtctgaa
    10141 tggtgtaagt tgatgtaaaa caataaattc ccttcatcac cctttttatg gtgtggtttt
    10201 tattgattta aatcaaagaa tgaagggtga tcgaagggta tatatacact caagcaacaa
    10261 tggttttacc aattggccgg gattaggccg accgaaatca aataattttg cctggggagg
    10321 catcacatga ttacaggtat ccagattact aaagccgcta acgacgacct gctgaattcc
    10381 ttctggctgc tggacagcga aaaaggcgaa gcgcgctgca tcgttgcaaa atccggcttt
    10441 gctgaagatg aagttgtggc tgtcagcaaa ctgggcgaga ttgaataccg tgaaattccg
    10501 atggaagtta aaccggaagt acgcgttgaa ggcggtcagc atctgaacgt taacgttctg
    10561 cgtcgtgaaa ctctggaaga cgcggttaag catccggaaa aatacccgca gctgactatt
    10621 cgtgtttctg gttatgcggt gcgttttaac tccctgacgc cggaacagca gcgcgacgtt
    10681 atcgctcgta cctttaccga aagcctgtaa ggcttatccg gtaataacaa gcggaagagg
    10741 ccgggccttt tccgcttttg ttttatttgt gtcagtaaaa aatccgcacc gcgcagtaca
    10801 ccagcagtaa cgccagaatg atatttaact ggcgaccata atggcgaaac gcccgctgaa
    10861 acagatgtcc cgccagcgcc cagcacacat taccgaacgt gccgatcaat gccagcaata
    10921 tactgacgcc gatgacccag ttcagcgcct gcgtttgcgg taaaacaaat gtagacagag
    10981 cggtaatgcc gtacagaata attttgacgt tcacaaactg caggccaaag cttacccaaa
    11041 agccaaccgg ttttggtctg accttctcat ccgccgctgg actggtggca attttccacg
    11101 ccagccacag gatatacgca gcccctaccc aactgagcaa atgaatgatt gccggatcga
    11161 taaccgcaag ggaaaacgcg atcccggcgc acagcagcat gacgaccaaa aatcccagac
    11221 tcatacctgc cagtacacga atactctgcc gaaaaccatg tgcagttgct gcgctaagcg
    11281 cgagaatatt gtttgggccg ggggtaaggg cggtgattaa tgtataagtc cagaaagcgc
    11341 ttaaaagcat cggtgtcact tgtcatctcc tctgttttag cagacagtac ccgatatgaa
    11401 atatttaaaa aaatgaatgt tttttaattc tgaattcgag attttcgata ggttggtggt
    11461 tatggatctg cgtcggttta ttacgctgaa aacggtagtg gaagagggct cgtttctgcg
    11521 ggcttcgcaa aagctgtgct gtactcagtc gacggtaact tttcatattc aacagcttga
    11581 acgtgagttt tccctgcaac tgttcgagaa aatagggcgc cgaatgtgcc tgaccaatga
    11641 ggggaaaaag ctgataccgc atatccatga actgacgcgt gtgatggagt cgattcgtga
    11701 agccgcaaga caggatgcgg aacccggcgg agagctgcgc gtggcgacag gtgaaacctt
    11761 actggcatac aaaatgccgc aggttttaca acgttttaag ctgcgagcgc cgaatgtcag
    11821 attgtcgcta cagtcgctga attgctatgt gatacgtgat gcgttgctga atgacgaggt
    11881 cgatctgggc gttttttatc gcgtaggtaa tgatgacgcg ctcacgatgc agcaactggg
    11941 ggagcagccg ctggcgctgg tggcctctcc actgctacag gatgctgatt ttacgcagcc
    12001 agatcagcat atccctgcag cttcatcatc aatgaaccgc aatgtgtctt ccgccagcta
    12061 tttgaaagta cgctacggca gaggcggatt acgctggaaa acaccattga actgtggagt
    12121 attgaaagca ttaaacagtg tgtggctgct aacctgggca tcagcttttt accgcgattt
    12181 gccgttgaac gagaacttag caccggtcag ttgaaagagc tgccgtttgg cgcgccgtcg
    12241 ctatcgatca tggcgctgtg cgcccatcat gccgggaaag cggtcagccc ggcaatgcag
    12301 atatttatgc agtgtatgga ggcgtgtttt accgtggaag ataaaaaatg ccgggttaac
    12361 gaacccggca ttatcatcac tcttcgctgg attgctcctg cattttcgta ccgcttggct
    12421 tgcggcgctt accgatattt tttgtatcgc ggtaacgttt cttcacgcgc ggcttctctt
    12481 tttctttctc ttttttcttc tcggcgcgtt tcgccagcac ttttttcgac ggtttgccgg
    12541 tcagcttttc gctgggcgca cgcgtggtcg ggcgaagctc atcaatgacg cgcgctttta
    12601 gcggctcttc gatgtagcga ccgattttca gcagcaacag atggtcgtgg gcttcaacca
    12661 gcgagattgc agtgcctttg cgacccgcac ggcctgtacg accaatgcga tgcagatagg
    12721 tatcgccact gcgcggcatg tcgaagttaa tgacgtggct gacgtcagga atatcaatcc
    12781 cgcgtgccgc gacgtcggtc gcgaccagca cgttaacgcg accgtcggtg agacgcttaa
    12841 taccctcgtt acgtttgatc tgcgccatct cgccttcaag atagcaattg ttgatccctg
    12901 ccagacgcag cgtttcagcc agttcatgga cgcgttcacg tttacgtaca aacacgatag
    12961 aacgggttgc atcgtcttgt tttagcaggt gcttcaacag cgcaacttta tgttcgaaat
    13021 tgtcggcacg gtagtaccac tggtgaattt tcttgcgctc gcgggttgac ggattggcgg
    13081 aaacctcaac cgggtcttcc agcaggcgct cggcaaaatc tttaatcgca tcgccttcca
    13141 gcgtggcgga gaacagcatc gtctgtttac gccagcgggt ctcaccagcg atatgttcaa
    13201 tgtcctgagc gaagcccatg tcgagcatcc ggtcagcttc gtcaaggatc agtgtttcaa
    13261 ccgcccggca gtcaaaattc tcttctttta tatattgcag cagacggccc gtcgtggcga
    13321 ccacgatatc ctggttttcg ctaaacactt cagcatggtt catataggcc acgccgccgg
    13381 taatcgtggc gatatccaga tgagtatgct tagccagttc acgagcgtga tcggcaacct
    13441 gcattgccag ttcgcgggtt ggcgtcagga tcagaatgcg cggcggcccc gattttttac
    13501 gcggaaagtc gagcaggtgc tgcaacgccg gcagcagata tgccgccgtt tttccggtgc
    13561 ctgtcggcgc agaaccgagt acatcacggc catcgagcgc aggcggaatg gcggcagcct
    13621 gaatggcggt cgggcgagtg aaacctttat cctggagggc atccagcagg ctttcgtcga
    13681 gttcaagttc ggaaaaagtc gttacagtca tgttctacct ctgtgtgggg cgctgattat
    13741 agacgttacg gccgcaatct tcatctgttt gtatggatat cccttctcag gtattgtttt
    13801 cactcggcgc tgtcgccgtt ttttgcaagg ttgtttttac atgtctcagt ctggctccgt
    13861 tcttcgtcgt aacggattta cgtttaaaca gttttttgtc gcacacgatc ggtgtgcgat
    13921 gaaagtggga actgacggta ttttactcgg ggcgtgggcg ccggtcgcgg atgtaaagcg
    13981 aattctggat atcggtactg gaagcggtct gctggcgtta atgctggcgc agcggacgga
    14041 tgacagtgtg cctgttgacg ccgtggaact ggatgccggg gctgccatgc aagcgcagga
    14101 aaacgtggct cactctccat ggccgcatcg aataacggtg catactgacg atattcagcg
    14161 ttgggcgcct cgccagacgg tacgctttga tcttattatc agcaacccgc cttattacga
    14221 acccggtgtg gaatgctcca cgccgcagcg ggagcaggcg cgttacaccg ctacgctgga
    14281 tcaccagacg ttattggcta ttgcggcgga ttgtattacc gaagatggct ttttttgcgt
    14341 agtcttgccg gaacaaatag gtaacgcttt tacgcagcaa gcgctcaaca tgggatggca
    14401 tttgcggtta cgtactgacg ttgcggaaaa cgaagcgcgc ttgccgcacc gggttttgct
    14461 cgcattctcc ccgcaagccg gggagtgctt tagcgacaga ttagtaattc gcgggtcaga
    14521 ccagaattat tctgaaagtt atacggcgct gacccaggca ttttatctgt ttatgtgagg
    14581 cgttaacggc gaaaggatcg atgggcctga ttcagccagt tgttgcggat aatccagcgt
    14641 aaagtgcagc ccccggctct ctttacgcat catcgcgcaa cgcacaatca gttcggccac
    14701 ttgcaccaga ttgcgcagct ccagtaaatt attcgagacg cgaaagttgg cgtaatattc
    14761 gtcaatctct tgttgcaaca tagtaatacg ccgtagggcg cgctccagcc gtttcgtcgt
    14821 gcgcacaatc cccacatagt cccacatcag cagacgcagt tcgtgccagt tatgctgaat
    14881 caccacccgc tcatcggcgt tctccacgcg gctttcatcc caggcgggaa ggacgtcaac
    14941 gctgtggaca gaaggcattc gcctgtcgat atccattgcc gcggaccagc cgtacactaa
    15001 gcattccagt aacgagttgg acgccatacg gttagcgccg tgcagaccgg tgtaactgac
    15061 ttcgccaatg gcatataagc cgtctacatc ggtacgacca taatcatcga cgaccacgcc
    15121 gccgcaggta tagtgcgcgg caggaacaat gggaatcggt tctttggtta aatccatccc
    15181 caaatcgagc agtttcgcat agatcatcgg gaagtgctgg cggacaaaat cgtcaggctt
    15241 gtggctgata tcgagaaaca tacagtctgc gccgagtcgt ttcatctcat gatcaatagc
    15301 gcgggcgaca atatcgcgcg gcgccagttc gccgcgttcg tcaacgtccg gcataaaccg
    15361 tgaaccgtcc ggacgtttaa ggtatgcgcc ttcgccgcgc agcgcttcgg taaggagaaa
    15421 attacgcgcc tgcgggtgat aaagggcagt gggatgaaac tggttaaatt ccagattagc
    15481 gacccgacag cccgcgcgcc aggccatcgc gataccgtca ccggaggaaa tatccgggtt
    15541 agtggtatat tgatacacct ttgaggcgcc gccggtcgcc agcaccaccg acttcgcatg
    15601 acaggtttca acccactctt tattgcgatt ccagatccag gcgccgacga cccggcgagg
    15661 ccccggcaga cctattttat cggagataat taaatcaacg gcgttgctgc gttccagcac
    15721 ctgaatatta ggatgatttt gtgcccgact gaccaacgtg gtttcgactt cctttccggt
    15781 agcgtcggcg gcatgaagga tacggcgatg gctatggccg ccttcacgcg tgagatgata
    15841 gctctccttg ccgtttggct ggacatgcgt atcaaacagg acgccctgat cgataagcca
    15901 ctgcacgcag gtacgagcgt tgctggcgac aaactccacc gcgtggcgat cgcaaattcc
    15961 ggcgccggca atcagcgtat cttcgacatg cgatgcaatg ctgtcggttt catcaaacac
    16021 ggcggcaata ccgccctgtg cataaaacgt ggagccctcg ctcaccggcc ctttactcag
    16081 gacgataacc ttatgctttt cagccagacg cagcgccagc gagagtccgg ccgcgccgct
    16141 gccgataatt aacacatcac aggacagttc aggagttgtc atcatggttc ttgtttaatt
    16201 tactaaacat ggttgcggca gattagcact atatggcgct aaaaagcacg ttatgatttc
    16261 aaaagtgttg tgcttattaa acataaaata aaaatacggc gagagataaa cggcaaaaaa
    16321 tattttatag ggcagggtgt tagcgtcgga ttttgtagtg aaataaagat gctgttaggt
    16381 tactctgcaa acgacgaaat gggcatttct gtacagatag tgcgttgttc agcatctgta
    16441 gacttataat ggaagataag acctgtctac aacatgacaa acaaaaacaa atgcgtaacg
    16501 gaactttacg aaacatagac actctaacct gttgcttgct catagtgcgg cttatggagt
    16561 ggcgtttcga aagcgcgtgg aaatttggtt tggggagaca ttacctcgga tgagcgagca
    16621 gttaacggac caggtcctgg ttgaacgggt ccagaaggga gatcagaaag cctttaactt
    16681 actggtagtg cgctaccagc ataaagtggc gagtctggtt tcccgctatg tgccatcggg
    16741 cgacgttccc gatgtcgtac aggaatcatt tattaaggcc tatcgcgcgc tggattcttt
    16801 ccggggggat agcgcttttt atacctggtt gtatcgtatt gcggtcaata ccgcgaagaa
    16861 ctacctggtt gcgcaggggc gtcgtccgcc ttccagtgat gtagacgcga ttgaagcaga
    16921 aaactttgaa agcggcggcg cgctgaaaga aatttcgaac cctgagaact taatgttgtc
    16981 agaagaactg agacagatag ttttccgaac tattgagtcc ctcccggaag atttacgtat
    17041 ggcaatcacc ttacgggagc tggatggcct gagctatgaa gagatagcgg ctatcatgga
    17101 ttgcccggtg gggacggtgc gttcacgtat cttccgggcg cgggaagcta ttgataataa
    17161 agttcaaccg cttatcaggc gttgacgata gcgggatact ggaaaaggta ttaggcatgc
    17221 agaaagaaaa actttccgct ttgatggatg gcgaaacgtt ggatagtgag ctgctcaaag
    17281 cgcttacgca cgactcggaa atgcagaaaa cctgggagag ttatcacctg atccgcgatt
    17341 caatgcgggg ggatacgcct gacgttctcc atttcgatat atccgcccgc gtgatggccg
    17401 ctattgaaaa cgagccagta cgtcaggtga cgccattaat ccctgaggcc caacccgctc
    17461 cgcagcaatg gcagaaaatg ccgttctgga aaaaagtgcg tccgtgggcg gcgcagctta
    17521 cccaaatggg cgtggcggcg tgcgtttcac ttgcagttat cgtcggtgtc cagcactata
    17581 atgggcaatc tgaaacatcc caacaacctg aaacgccggt tttcaatacc ctgcctatga
    17641 tggggaaagc cagcccggta agtctgggag tgccttctga agcagcgcct gtcggcagtc
    17701 agcaacagca ggtacaggag cagcgtcgtc gcattaatgc catgttgcag gactatgaac
    17761 tgcagcgccg actgcactcc gaacagcttc agtttgagca ggcgcaaacc cagcaagccg
    17821 cggtacaggt gccaggaatc caaactttag gaacgcaatc gcagtaatga agcaactttg
    17881 gtttgccatg tcccttgtgg cggctagcct gttcttctca gtaaacgcct cggccgaccc
    17941 tgcgtccggg gcgttattgc agcagatgaa catcgccagt cagtcactga attacgagct
    18001 gtcattcgtc agcatcacga aacaaggcgt tgaatctctg cgttatcgac acgcacgcct
    18061 ggatagtcgc ccgcttgcgc aattgctaca gttggacggt ccccgccggg aggtcgtaca
    18121 gcgtggtaat gaaatcagtt attttgaacc gggccttgag ccgttcaccc tgaacggtga
    18181 ttatattgtc gattctctgc cttccctgat ttacaccgat ttcaagcgtc tggcgcctta
    18241 ctacgacttt atttccgtcg gacgcacccg tatcgcagac agattatgcg aagttatccg
    18301 cgttgtggcg cgcgatggta cgcgttacag ctatatcgtc tggatggaca tggacaccaa
    18361 actaccgatg cgcgttgatc tgctggatcg cgacggcgag acgctggagc agttccgcgt
    18421 tattgcgttc acggtgagtc aggatatcgg cagcaccatg caggcgctgg cgaaggcgaa
    18481 tctgccgccg ctgctttctg ttcccggtgg cgaaaaaacg aaatttaact ggaatccatc
    18541 ctgggtgccg caaggcttta gcgaagtttc cagcagccgt cgtccgttgc cgacgatgga
    18601 taacctgcct atcgaatcgc ggctttattc tgacggtctg tttagctttt ccgtcaatgt
    18661 gaaccgggcg acgcaaaaca gcagcgatca gatgctgcgc accgggcgcc gaacggttta
    18721 tagcagcgtt cgcgacaacg cggaaatcac cattgtcgga gagcttccgc cgcaaacggc
    18781 gaagcgcatt gccgacagta tcaaattcag ggcagtacaa tgattaaaga gtgggcaacc
    18841 gttatctcct ggcagaatgg tcaggcggtg gtgagctgcg acgttaaagc gtcatgcagc
    18901 agctgcgcct cccgtgcggg atgcggcagt cgcgtgctga ataaattagg gccgcaaacc
    18961 acgcatacca ttgttgtgcc aagcgcggag ccgctggctc cggggcagaa agtcgagttg
    19021 ggcatcgccg aaaaaagcct tttaggttcg gcgttgctgg tctatatgtc gcctttagcg
    19081 gggctatttc tttgtgcggc gctttttcag atgctgtttg gatctgacct tgccgcatta
    19141 agcggggccg tgctgggcgg agtgggcggt tttctggttg cccgcggcta ttcccgaaaa
    19201 ctggcggagc gcgacgcctg gcagcccgtg attttaaacg ttgccctccc gcctgacctt
    19261 gtccgcgtcg aaactacctc aatcgaaacg cgccagtaaa cgttttgccc aatggtacat
    19321 ggtacacctg ccgcgttggg ttgttgtccc gataagcatg cgcttttcct gcgttgcggt
    19381 gttttacagg aaaaaagcga ggcgttttcc agttcccgct ctccttacac tatgaacatt
    19441 tcctcgcctt agcgttgtag tgtagaatgc ggcgtttcag ttaaaacaga cgttaagctc
    19501 agaacagcga cctctaaagt ctggtcaacc aggcgtaagg cataataatt tatctctatg
    19561 aagaacatac gtaacttttc gatcattgct cacattgacc acggtaaatc gacgctgtct
    19621 gaccgtatta tccaaatctg cggtggcctg tctgaccgtg aaatggaagc tcaggtactt
    19681 gattcgatgg atcttgagcg tgagcgcggt attactatta aagcccagag tgtgacgctg
    19741 gattttaaag cgtctgatgg tgaaacttat caactgaact ttatcgacac gccgggacac
    19801 gttgactttt cctatgaagt ttcccgttcg ttagccgcct gcgagggcgc gctgctggtg
    19861 gtggatgccg gccagggcgt agaagcgcaa acgttggcga actgctacac cgcgatggaa
    19921 atggatcttg aagtggtgcc ggtgcttaac aagattgacc tgccggccgc cgatccggag
    19981 cgtgtggcgg aagaaatcga agacattgtc ggcatcgatg cgacggacgc ggtacgctgc
    20041 tccgccaaaa cgggtgtcgg cgtgacggac gttctggaac gcctggtgcg cgatatcccg
    20101 ccgccgcaag gcgatccgga cggcccgctg caggcgctga ttattgactc ctggttcgat
    20161 aactacctgg gcgtggtatc cctggtgcgt attaaaaacg gcaccatgcg taaaggcgac
    20221 aaaattaaag tgatgagcac cgggcagacc tacaacgctg accgcctggg gatcttcacg
    20281 ccgaaacagg ttgatcgtac cgagctgaag tgcggcgaag taggctggct ggtctgcgcc
    20341 attaaagata tcctcggcgc gccggttggc gataccttaa cctcagcgcg taacccagct
    20401 gaaaaagcgt tgccgggctt taagaaggtg aaaccgcagg tctatgcagg tctgttcccg
    20461 gtcagctccg acgattatga aagtttccgc gacgcgctcg gcaagctgag cctgaacgat
    20521 gcctcactgt tttatgaacc ggaaagctcc tcggcgctgg gctttggttt ccgctgcggc
    20581 ttcctcggcc tgttgcacat ggagatcatt caggagcgtc tggaacgcga atacgatctg
    20641 gatctgatca ccactgcgcc gaccgtggtt tatgaagtag aaacaacggc gaaagagact
    20701 atctatgttg atagcccctc caagctgccg ccgttgaata acatttatga actgcgcgag
    20761 cctatcgccg aatgtcatat gctgttacca caagcctatt taggtaacgt tattacgctg
    20821 tgtattgaga aacgcggcgt acaaactaac atggtgtatc acggtaacca ggttgcgttg
    20881 acctatgaaa tcccgatggc ggaagtggtg ctcgacttct ttgaccgtct gaaatcaacg
    20941 tcgcgcggct atgcgtctct ggattataac ttcaagcgct tccaggcttc cgatatggtg
    21001 cgtgttgatg tgttaatcaa caacgagcgt gtcgatgcgc tggcgctgat cacgcaccgt
    21061 gataactcgc aaagccgtgg tcgcgagctg gtggagaaaa tgaaagattt gattccacgc
    21121 cagcagtttg atatcgcgat tcaggcggcg attggtacgc atattattgc ccgttcgacg
    21181 gtaaaacagt tacgtaaaaa cgtgctggcg aagtgctacg gcggcgatat cagtcgtaag
    21241 aaaaaactgc tgcagaaaca gaaagaaggt aagaaacgca tgaagcagat cggtaacgtc
    21301 gagctgcctc aggaggcgtt cctcgccatt ctgcatgtcg gtaaagacaa taaataatcc
    21361 ctaaggagtt ggcatggcga acatgtttgc cctgattctg gtgatagcca cactggtgac
    21421 gggcatttta tggtgcgttg ataagtttgt tttcgcgcca aaacgtcggg cgcgccaggc
    21481 tgccgcgcaa acggcgtcgg gagatgcgct ggataacgct acgctcaata aagtggcgcc
    21541 taagccgggc tggctggaga ccggggcgtc ggttttcccg gttctggcga tcgttctgat
    21601 cgttcgttca tttctttatg aaccctttca gatcccgtca ggctcaatga tgccgacact
    21661 gcttatcggc gattttattc tggtggaaaa atttgcctac ggcattaaag atccgatcta
    21721 ccagaaaacc ctgattgaaa ccggtcatcc aaagcgcggg gatattgtgg tatttaaata
    21781 tccggaagat cctaagttag attacatcaa acgcgccgtc ggtttgccgg gcgataaaat
    21841 cacttatgat ccggttgcga aagaggtgac gattcagcct ggctgtagct ccggtcaggc
    21901 gtgcgaaaat gcgctgccgg ttacctactc taacgttgag ccgagcgatt ttgtacagac
    21961 ctttgcccgc cgtaacggcg gagaagcgac cagcggtttc tttgaggttc cgctaaacga
    22021 gacaaaagaa aacggcattc gcctgaccga acgtaaagag acgttaggcg atgtgaccca
    22081 ccgcatcctg atggtgccga tagcccagga tcagttgggc atgtattacc aacagccagg
    22141 acaaccgctg gcgacctggg ttgtaccgcc ggggcaatat ttcatgatgg gcgacaaccg
    22201 cgataacagc gcggatagtc gttactgggg atttgttccg gaagcgaatc tggtcggtaa
    22261 agcggtcgct atctggatga gctttgacaa gcaggaaggg gagtggccga caggcgtacg
    22321 cctgagtcgt atcggcggta ttcactaact gtggcgaaat gatcgttcac gctgtcgtct
    22381 ttttagcggc agcgtgaatt atttcctgga taaattccct cagactaacg acatcccctg
    22441 tcgttgtgta tagaatattc ccccgaagtt ttaggttggc gccgtttggt cgccacggca
    22501 cacgaaacag cgttggttat agacaacctt ctttccgctg cagcgatgcg gcaggacaga
    22561 tgacgtgtat caggtctgtt tcgtgtgctg gattgttgac gcattcattt attggtatcg
    22621 catgaacccc atcgtaatta atcggcttca acggaagctg ggctacactt ttaatcatca
    22681 ggagctgttg cagcaggcat taactcaccg cagcgccagc agtaaacata acgaacgcct
    22741 ggagttttta ggcgattcaa tcctgagctt cgttatcgct aacgcgcttt atcaccgttt
    22801 tccacgggtg gatgagggag atatgagccg tatgcgcgcc acgttggtac gtggtaatac
    22861 gctggcggaa ttagcccgtg aatttgattt aggcgagtgc ctgcgtttag ggccgggcga
    22921 attaaaaagc ggcggatttc gtcgggagtc cattctggcg gacaccgtgg aagcgttaat
    22981 cggcggagta tttctcgata gcaatatcca gaccgtcgag cagttaatcc ttaactggta
    23041 taaaacccgt ctggatgaga taagtccggg cgataaacaa aaagatccta aaacgcgctt
    23101 gcaggagtat ttgcagggtc gccatctgcc gctgccatct tacctggttg tgcaggtacg
    23161 cggcgaggcg cacgatcagg aatttactat ccactgccag gtcagcggcc tgagcgaacc
    23221 ggtggttggc acgggttcca gccgtcgtaa ggcggagcag gctgccgccg aacaggcgct
    23281 gaaaaaactg gagttggaat gagcaccgac aaaacttact gcggatttat tgccatcgtc
    23341 ggacgtccga acgttggcaa atccaccttg ctgaacaaac tgctcgggca gaagatttcg
    23401 atcacttccc gtaaagcgca gaccacgcgc caccgcattg tcggtattca taccgaaggc
    23461 ccgtatcagg caatctatgt cgataccccg ggactgcata tggaagaaaa gcgcgccatt
    23521 aaccgtttga tgaataaggc ggcgagcagt tcgattggcg acgttgagct ggtgattttc
    23581 gttgtagaag gcacccgttg gacgccggac gacgaaatgg tcctgaacaa actgcgcgat
    23641 ggcaaagcgc cggttattct cgccgttaac aaggtggata acgtgcagga aaaagccgat
    23701 ttgctgccgc acctccagtt cctggcaagc cagatgaact ttcttgatat cgtccccatc
    23761 tctgctgaaa cgggtatgaa cgtcgatacc attgccagta tcgtgcgtaa acatttaccg
    23821 gaagcgattc accacttccc ggaagattat atcaccgatc gctctcagcg ctttatggcg
    23881 tctgaaatca ttcgtgaaaa gctgatgcgt tttctcggcg ccgagctgcc gtattccgtt
    23941 accgttgaga ttgaacgttt tgttaccaac gaacgcggcg gctatgatat caacgggctg
    24001 atcctcgtcg agcgcgaagg gcagaagaag atggtgattg gcaacaaagg cgccaaaatc
    24061 aaaaccattg gtattgaagc gcgtaaagac atgcaggaga tgtttgaagc gccggtacac
    24121 ctggaactgt gggtgaaagt gaaatccggc tgggccgatg acgaacgcgc tctgcgcagt
    24181 ctcggttacg tagacgatct gtgagttaac acagcgtgga agggtggcag cgcgcatttg
    24241 tcctgcacag tcgcccctgg agcgaaacca gcctgatgct ggacgtcttc acggaagaat
    24301 cggggcgcgt gcgccttgtc gccaaaggcg cgcgatctaa acgttccaat ctgaaaggcg
    24361 cgttgcagcc ttttacgccg ttattgctac gctacagcgg acgcggcgag gtgaaaaccc
    24421 tgcgcagcgc cgaggcagtt tctctggcgc tgccgttaag cggtattacg ctctatagcg
    24481 gcctgtatat caacgaactc ctctctcgcg tactggaata tgaaacgcgc ttctccgaac
    24541 tcttttttga ttatctgaac tgtattcagg cgctggcggg aaccaccggc tcgcctgaac
    24601 cggcgttgcg acgtttcgaa ctggcgttgc tgggacatct ggggtatggc gtcaatttca
    24661 cccactgtgc aggcagcggc gaacgggtgg atgacaccat gacctaccgt taccgcgaag
    24721 aaaaaggctt tttcgccagc gtcgtcatcg ataacaacac ctttaccgga cggcacctga
    24781 aagcgctgga ggcgcgggaa tttccggatg tagataccct gcgtgccgct aaacgcttta
    24841 cccgtatggc attaaagccg tatcttgggg gaaaaccgtt aaaaagccgg gagctgttcc
    24901 ggcaatttat gcccaaacgc acagtaaaaa cgaagaaaga ttaacgagga ttgtcatggc
    24961 tgaattactg ttaggcgtca atattgacca cattgccacg ttacgtaatg cgcgcggcac
    25021 cgactatccg gatccggtac aggcggcgtt tattgctgaa caggcaggcg cggacggcat
    25081 taccgtacac ctgcgcgaag atcgtcgcca cattaccgat cgcgatgtgc gcattctgcg
    25141 tcagacgctg catacgcgta tgaatctgga gatggcggtg accgaagaga tgctggcgat
    25201 cgccgtagaa accaggccgc atttctgttg tctggtgccg gaaaaacgcc aggaagtcac
    25261 caccgaaggc ggcctggatg tggccggaca gcgcgataaa atgcgtgatg cctgtgcgcg
    25321 cctagcggcg gctggcatcc aggtttcgct ctttatcgat gccgatgaaa ggcaaatcaa
    25381 cgcggcggcg gaagtcggcg cgccgtttat cgaaatccat accggctgct atgccaacgc
    25441 agaaaccgat gcggaacagg caaaagagct ggcgcgtatt gccagcgccg cgaccctggc
    25501 ggcccgtctg gggctaaaag taaatgcggg tcatggcctg acctaccata acgtcaaagc
    25561 tattgccgca ctgccggaaa tgcacgagct caatatcggt catgccatta ttggtcgggc
    25621 ggtgatgacg gggctgaaag aggcggtggc tgaaatgaaa cgtttgatgc tggaagcgcg
    25681 cggctaatgg cgattctcgg cctgggaacg gatattgtag agattgcccg cattgaggca
    25741 gtgatctccc gttccggcga acgtctggca aggcgtgtgc tcagtgacaa cgagtgggct
    25801 atctgggaga cgcatcagca gccggtgcgt tttctcgcca agcgttttgc ggtcaaagag
    25861 gcggcagcga aagcttttgg caccggcatc cgcaacggtc tggcgtttaa tcagttcgaa
    25921 gtgtttaacg atgagctggg aaaaccacgt ttgcggctgt ggggcgaggc gttaacgctg
    25981 gcggaaaaac tcggtgtggc gcacatgcat gtcacgttgg ccgatgaacg ccattacgcc
    26041 tgcgctacgg tcattctgga aagttagatt tgccggatgg cggcgtaaac acgttatctg
    26101 acctacaggc cgatatattg ccggcctgat aagcatagcg ccatcaggca ttgttgcgtt
    26161 ggaagtgcgt taacccgctt acaatttatc tgcgtgatgc atcagaacaa acttatccca
    26221 caactgttct tcggtttcga catgggcggg atcctgcaaa atcgtattgg ggatcgggca
    26281 gactttctga caggtcggcg tttcgtaatg gcctacacac tcggtgcatt tgtcgctgtt
    26341 aatctcataa atgctgtcgc ccattgaaat cgcctcattc gggcactccg gctcgcacat
    26401 atcgcaattg atacattttt tggtgattaa cagcgccatc aggaaattct cagaaacaac
    26461 acaaatcggg cgggcattat acgcctattt tctactcggg ccagctcttt tctggcgctg
    26521 atttgttatc tacagtgtaa aaatttttga tctgcttgag caggcagatg gttgcgttat
    26581 ccagtgaaag gtcattactg tgcaccagca tgacaggaat aaagaatgcg gggatgccca
    26641 gtgaaaccag gcgaacattt ttgggtgtcg ataaatgggt tagcgagcgg gtaataaatg
    26701 cgatgccaat ctgcgcttcg gcatactcaa ggcatgagta gtggttatcc agttcgcaga
    26761 tgacgttagg aacgactttg cggttattaa attctgtggt gatgctccct cttaatagca
    26821 gagagtcatt aagcacgata atgggctggt cgtttaaatc ttttagatgc agacgttcgc
    26881 gtgtcgccag aggatgagaa agtgggattg cagcgataat ttcatcttca aacagcatgg
    26941 tcgagcttag ctgggcaggg agcgctgttc gataaacaat gccaatatca acggcgctat
    27001 ccgtcagctt tttaatggtt tgctcagttg agaactcttt aacatttaaa gatatttccg
    27061 gatggtgcgc cataaagttg cgaaaagcgg gcaggaccag gtagctgcct gacaccccga
    27121 ttgaaatagt atcgcgctgt tgatcctgat agggaagaag ttcattttcg gcatttttta
    27181 aatccagcat tattttgtta gcgtgtcgtt gcaaaataat gcctgctttt gttaatttaa
    27241 ttcctctgcc ttttcgctta aataatattg ttttaagtga tgactcaagt tgtttgattt
    27301 gctgacttaa tgatggctga gtgataaata ggcgactg
//
LOCUS       DAJVBX010000033        27325 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.033, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000033 DAJVBX010000000
VERSION     DAJVBX010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 27325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27325
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.033"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            171..2384
                     /locus_tag="OPV72_001270"
     CDS             171..2384
                     /locus_tag="OPV72_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor domain-containing phosphodiesterase"
                     /protein_id="HCR9913625.1"
                     /translation="MKLNKTYINIRDKWWGLPLILPSILLPVLSSANTYALTSTGNVV
                     LFYLPLAFMLSLMLFFGWAALPGIVLAIFWRRYPQTGLYETLSVTMHFIITIVLSWGG
                     YRVFSPRRNNVSHGDAHLLFQRMFWQVFCSATLFLVIYQFAAFVGMYESKASLMGVMP
                     FNINTLINYQALLVGNLVGVPLCYFIIRTLRNPLHLRGYYQQLKLQIDSKATKKEIVI
                     WLAVLTTLMFILCMPLTDNSSIFSTNYTLSLLLPVMLWGAMRYGYKFISIIWAVVLIT
                     SIHYYQRYMPWYSGYDTQLAITSSSYLVFSFIVNYMSVLATRQRVVSGRARRLAYLDP
                     VVHLPNLRALNRALKNAPWSTICFLHVPGLELLGKNYGVMLRIQYKQKLSHWITPMLA
                     SNECVYQMSGHDLVLRLNTEAHQQRIEALDKHIKQFRFIWDGLPLQPPVGVSYCCVRS
                     PVSHLYLLLGELSTSSDLSLTTNAPEDLQRRGAMHLQRDLKGRIAMMNRLQQALEHDH
                     FFLMAQPIFGVRGDVYHEILLRLRDDNGDVINPDNFLPVAHEFGLSSAIDLWVIENTL
                     RFMAASREYMPAHRFAINLSPTSVCRARFPAEVKQLLTQYQVEPWQLVFEVTESNSLT
                     NAEQAQLTLGQLQQFGCQIAIDDFGTGYASYARLKNVDADILKIDGSFIRNIVSNSLD
                     YQIVASICHLARMKNMQVVAEYIESEEIRSVVLSLGIDYLQGYLIGEPQLLSEIQ"
     gene            complement(2420..3961)
                     /gene="ppx"
                     /locus_tag="OPV72_001271"
     CDS             complement(2420..3961)
                     /gene="ppx"
                     /locus_tag="OPV72_001271"
                     /EC_number="3.6.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exopolyphosphatase"
                     /protein_id="HCR9913626.1"
                     /translation="MPIYDKSPRPQEFAAVDLGSNSFHMVIARVVDGAMQIIGRLKQR
                     VHLADGLGADNKLSEEAMERGLSCLSLFAERLQGFSPSSVCIVGTHTLRQAQNAADFL
                     KRAEKVIPYPIEIISGNEEARLIFMGVEHTQPEKGRKLVIDIGGGSTELVIGENFEPR
                     LVESRRMGCVSFAQLYFPGGVINKENFQRARMAAAQKLETLTWQYRIQGWNVAMGASG
                     TIKAAHEVLLALGEKDGFITPERLDKLKSEVLKHRSFNALSLPGLSEERKAVFVPGLA
                     ILCGVFDALAIRELRLSDGALREGVLYEMEGRFRHQDVRSRTAKSLANQYNIDREQAR
                     RVLETTMQMYEQWQAQQPKLAHPQLEALLRWAAMLHEVGLNINHSGLHRHSAYILQHS
                     DLPGFNQEQQMMMATLVRYHRKAIKLDDMPRFTLFKKKQYLPLIQLLRLGVLLNNQRQ
                     ATTTPPTLRLTTDDSHWTLCFPHDWFSQNALVLLDLEKEQQYWEAVTGWRLNIEEESS
                     PEIAA"
     gene            complement(3966..6032)
                     /gene="ppk1"
                     /locus_tag="OPV72_001272"
     CDS             complement(3966..6032)
                     /gene="ppk1"
                     /locus_tag="OPV72_001272"
                     /EC_number="2.7.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate kinase 1"
                     /protein_id="HCR9913627.1"
                     /translation="MGQEKLYIEKELSWLAFNERVLQEAADKSNPLIERMRFLGIYSN
                     NLDEFYKVRFAELKRRIIISEEQGSNSHSRHLLGKIQSRVLKADQGFDGLYNELLLEM
                     ARNQIFLINERQLSVNQQSWLRHYFKHYLRQHITPILINRETDLVQFLKDDYTYLAVE
                     IIRGDTINYALLEIPSDKVPRFVNLPPETPRRRKPMILLDNILRYCLDDIFKGFFDYD
                     ALNAYSMKMTRDAEYDLVHEMESSLMELMSSSLKQRLTAEPVRFVYQRDMPAALVDVL
                     REKLTISRYDSIVPGGRYHNFKDFINFPNVGKANLVNKPLPRLRHLWFDKEKFRNGFD
                     AIRERDVLLYYPYHTFEHVLELLRQASFDPSVLAIKINIYRVAKDSRIIDSMIHAAHN
                     GKKVTVVVELQARFDEEANIHWAKRLTEAGVHVIFSAPGLKIHAKLFLISRKEGDDVV
                     RYAHIGTGNFNEKTARLYTDYSLLTADARITNEVRRVFNFIENPYRPVTFDYLMVSPQ
                     NSRRLLYEMIDREIANAQQGLPSGITLKLNNLVDKGLVDRLYAASGSGVQVNLLVRGM
                     CSLIPQLEGISDNIRAISIVDRYLEHDRVYIFENGGDKQVWLSSADWMTRNIDYRIEV
                     ATPILDPRLKQRVLDIIDILFSDTVKARFIDKELSNRYVPRGNRRKVQAQLAIYDYIK
                     SLEQPD"
     gene            complement(6221..6859)
                     /gene="purN"
                     /locus_tag="OPV72_001273"
     CDS             complement(6221..6859)
                     /gene="purN"
                     /locus_tag="OPV72_001273"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HCR9913628.1"
                     /translation="MNIVVLISGNGSNLQAIIDACEAKKIKGTLRAVFSNKADAFGLE
                     RAREAGIPAQALTADRFDSRDAFDRELIRKIDAYAPDVVVLAGFMRILSPMFVAHYYG
                     RLLNIHPSLLPKYPGLHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAND
                     SEDDITARVQTQEHAIYPLVIGWFAQGRLKMRDNAAWLDGRRLPPQGYASDE"
     gene            complement(6859..7896)
                     /gene="purM"
                     /locus_tag="OPV72_001274"
     CDS             complement(6859..7896)
                     /gene="purM"
                     /locus_tag="OPV72_001274"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001656828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HCR9913629.1"
                     /translation="MTDKTSLSYKDAGVDIDAGNALVDRIKGVVKKTRRSEVMGGLGG
                     FGALCALPQKYREPVLVSGTDGVGTKLRLAMDLKRHDAIGIDLVAMCVNDLVVQGAEP
                     LFFLDYYATGKLDVDTAASVINGIAEGCLQSGCALVGGETAEMPGMYHGEDYDVAGFC
                     VGVVEKSEIIDGSRVAEGDVLIALGSSGPHSNGYSLVRKIIDVSGCDPQTTLLEGKPL
                     ADHLLEPTRIYVKSVLELIENIDVHAIAHLTGGGFWENIPRVLPENTQAVINESSWQW
                     PAIFTWLRTAGNVSRHEMYRAFNCGVGMVIALSAPEADKALALLNEKGENAWKIGIIK
                     ASDSEQRVVIE"
     gene            8309..8935
                     /gene="upp"
                     /locus_tag="OPV72_001275"
     CDS             8309..8935
                     /gene="upp"
                     /locus_tag="OPV72_001275"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HCR9913630.1"
                     /translation="MKIVEVKHPLVKHKLGLMRENDISTKRFRELASEVGSLLTYEAT
                     ADLETEKVTIEGWNGPVEIDQIKGKKITVVPILRAGLGMMEGVLENVPSARISVVGMY
                     RNEETLEPVPYFQKLVSNIDERMALIVDPMLATGGSVIATIDLLKKAGCSSIKVLVLV
                     AAPEGIAALEKAHPDVELYTASIDQGLNEHGYIIPGLGDAGDKIFGTK"
     gene            9023..10312
                     /gene="uraA"
                     /locus_tag="OPV72_001276"
     CDS             9023..10312
                     /gene="uraA"
                     /locus_tag="OPV72_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HCR9913631.1"
                     /translation="MTRRAIGVSERPPLLQTIPLSLQHLFAMFGATVLVPVLFHINPA
                     TVLLFNGIGTLLYLFICKGKIPAYLGSSFAFISPVLLLLPLGYEVALGGFIMCGVLFC
                     LVSFIVKKAGTGWLDVMFPPAAMGAIVAVIGLELAGVAAGMAGLLPAQGQSPDTKTII
                     ISMVTLAVTVFGSVLFRGFLAIIPILIGVLAGYALSFALGVVDTTPIAQAHWFALPTF
                     YTPRFEWFAILTILPAALVVIAEHVGHLVVTANIVKKDLVRDPGLHRSMFANGLSTII
                     SGFFGSTPNTTYGENIGVMAITRVYSTWVIGGAAIFAILLSCVGKLAAAIQIIPLPVM
                     GGVSLLLYGVIGASGIRVLIESKVDYNKAQNLILTSVILIIGVSGAKVHIGAAELKGM
                     ALATIVGIGLSLIFKLISLLRPEEVVLEANDAESPHQ"
     gene            10383..11108
                     /gene="hda"
                     /locus_tag="OPV72_001277"
     CDS             10383..11108
                     /gene="hda"
                     /locus_tag="OPV72_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaA inactivator Hda"
                     /protein_id="HCR9913632.1"
                     /translation="MSSWVEVSLNTPAQLSLPLYLPDDETFASFWPGDNASLLAALQN
                     VLRQEHSGYIYLWAREGAGRSHLLHAACAELSQRGDAVGYVPLDKRTWFVPEVLDGME
                     HLSLVCIDNIECVAGDELWEMAIFDLYNRILESGKTRLLITGDRPPRQLNLGLPDLAS
                     RLDWGQIYKLQPLSDEDKLQALQLRARLRGFELPEDVGRFLLKRLDREMRTLFMTLDQ
                     LDHASITAQRKLTIPFVKEILKL"
     gene            complement(11135..11494)
                     /gene="arsC"
                     /locus_tag="OPV72_001278"
     CDS             complement(11135..11494)
                     /gene="arsC"
                     /locus_tag="OPV72_001278"
                     /EC_number="1.20.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461430.1"
                     /note="This arsenate reductase requires both glutathione
                     and glutaredoxin to convert arsenate to arsenite, after
                     which the efflux transporter formed by ArsA and ArsB can
                     extrude the arsenite from the cell, providing resistance;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (glutaredoxin)"
                     /protein_id="HCR9913633.1"
                     /translation="MTDTIKIYHNPRCSKSRDTLNLLKSNGVEPEVVLYLDTPADAAT
                     VRELLRMLGMSSARELMRQKEDLYKTLHLADSQLSEEALIQALVEHPKLMERPIVVAN
                     GQARIGRPPEQVLDILG"
     gene            complement(11534..12997)
                     /gene="bepA"
                     /locus_tag="OPV72_001279"
     CDS             complement(11534..12997)
                     /gene="bepA"
                     /locus_tag="OPV72_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-barrel assembly-enhancing protease"
                     /protein_id="HCR9913634.1"
                     /translation="MFRQLKKNLVATLIAALALGQVAPAFADPADTLPDMGTSAGSTL
                     SIGQEMQMGDFYVRQLRGSAPLINDPLLVQYINALGMRLVSHADSVKTPFHFFLINND
                     EINAFAFFGGNVVLHSALFRYADNESQLASVMAHEISHVTQRHLARAMEDQKRSAPLT
                     WVGALGSILLAMASPQAGMAALTGTLAGTRQGMISFTQQNEQEADRIGIQVLQRAGFD
                     PQAMPSFLEKLLDQARYSTRPPEILLTHPLPESRLADARNRANQMRPVVVQSSADFYF
                     AKARALGMYNSGRNQLTSDLLDQWSKGNVRQQHAAQYGRALQAMEASKYDEARKTLQP
                     LLSAEPNNAWYLDLATDIDLGQKRANDAINRLKNARDLRVNPVLQLNLANAYLQGGQP
                     KAAETILNRYTFSHKDDGNGWDLLAQAEAALNNRDQELAARAESYALAGRLDQAISLL
                     SSASAQAKLGSQQQARYDARIDQLRQLQERFKPYTKM"
     gene            13205..14272
                     /locus_tag="OPV72_001280"
     CDS             13205..14272
                     /locus_tag="OPV72_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCR9913635.1"
                     /translation="MLEMLMQWYRRRFSDPEAIALLVILVAGFSILFFFSGLLAPLLV
                     AIVLAYLLEWPTARLQAIGCSRRWAASIVLILFVGILLLMAFVVMPIAWQQGIYLIRD
                     MPGMLNKLSDFAATLPRRYPALMDAGIIDAMAENMRTRMLNMGDSVVKYSLASLVGLL
                     TLAVYLVLVPLMVFFLVKDKEQMLNAVRRVLPRNRGLAGQVWNEMNQQITNYIRGKVL
                     EMVVVGVATWLGFLLFGLNYSLLLAVLVGFSVLIPYIGAFVVTIPVVGVALFQFGLGT
                     EFWSCFAVYLIIQALDGNLLVPVLFSEAVNLHPLVIILSVVIFGGLWGFWGVFFAIPL
                     ATLIKAVVHAWPDGQVTDASS"
     gene            14549..15736
                     /locus_tag="OPV72_001281"
                     /pseudo
     CDS             14549..15736
                     /locus_tag="OPV72_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001667973.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            15804..17072
                     /locus_tag="OPV72_001282"
     CDS             15804..17072
                     /locus_tag="OPV72_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004090684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HCR9913636.1"
                     /translation="MTSISTLGAIAALVVAIVLILRKVSPAYGMMAGALVGGLIGGAD
                     LLQTVSLMVSGAQGIVNAVLRILAAGVLAGVLIESGAANTIAETIVRKVGETRALLAL
                     AIATLCLTAVGVFIDVAVITVAPIALSIARNAGLSKSAILLAMVGGGKAGNVMSPNPN
                     AIAASDAFHVPLTSIMLAGVVPGIVGLIIAYLLAKRLNNKGAGVADHEVTHHDDSVAR
                     PGFLVAISAPLVAIFLLSLRPFVGISIDPLIALPVGGLVGLLLMGRARHCNQYMVAGL
                     MRMAPVAIMLLGTGTLAGIIANSELKDVLIHGLTASGLPSWLLAPVSGAMMSMATAST
                     TAGTAVASGVFSPTLLELGVSALAGAAMIHAGATVLDHLPHGSFFHATGGSVNMQIHE
                     RLKLMPYETLVGLAITFISTLMFGFFGFAG"
     gene            17078..18217
                     /locus_tag="OPV72_001283"
     CDS             17078..18217
                     /locus_tag="OPV72_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HCR9913637.1"
                     /translation="MKIVIAPDSFKESLSAMAVAEAIEKGFREIYPDADYVKVPMADG
                     GEGTVQSMVEASGGRYVDQWVQGPLGQPVTARWGMLGDSDTAVIEMAAASGLHHVSPE
                     LRNPLNTTSYGTGELIVAALERGVKRIILGIGGSATNDGGAGMMQALGVILRDKQGRS
                     LSPGGEALAALASIDLSGCHPLLRKVSITVACDVNNPLCGPQGASAIFGPQKGATAEM
                     VNSLDAALENWGRHIYQATGREVINAPGAGAAGGMGAALLGLLNAELRAGVEIVVETL
                     QLEQAVKDADLVITGEGRLDSQSICGKTPIGVARVAKRHHKPVIALAGGLQHDHHVVY
                     QQGIDAALSILSHIVTLPEALHEAEYNLSLSARNVAAIWRLARQA"
     gene            complement(18264..18734)
                     /gene="bcp"
                     /locus_tag="OPV72_001284"
     CDS             complement(18264..18734)
                     /gene="bcp"
                     /locus_tag="OPV72_001284"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent thiol peroxidase"
                     /protein_id="HCR9913638.1"
                     /translation="MNPLKAGDIAPKFSLPDQDGEQVNLTDFQGQRVLVYFYPKAMTP
                     GCTVQACGLRDNMDELKKAGVDVLGISTDKPEKLSRFAEKELLNFTLLSDENHQVCEQ
                     FGVWGEKSFMGKTYDGIHRISFLIDADGKIEHVFNDFKTSNHHDVVLNWLKENA"
     gene            complement(18734..19306)
                     /locus_tag="OPV72_001285"
     CDS             complement(18734..19306)
                     /locus_tag="OPV72_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system transcriptional
                     repressor"
                     /protein_id="HCR9913639.1"
                     /translation="MTPSSQHYLVITALGADRPGIVNTITRHVSSCGCNIEDSRLAML
                     GDEFTFIMLLSGTWNAITLIESTLPLKGAELDLLIVMKRTSDRPRPAMPATVWVQVEV
                     ADSPHLIERFTALFNSHEMNIAELVSRTQPAEDDKAAQLFIQITAHSPASQNSANIEQ
                     AFKALCTELNAQGSINVVNYSQHDEQDGVK"
     gene            19452..20330
                     /gene="dapA"
                     /locus_tag="OPV72_001286"
     CDS             19452..20330
                     /gene="dapA"
                     /locus_tag="OPV72_001286"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001311023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HCR9913640.1"
                     /translation="MFTGSIVALVTPMDEKGNVSRSCLKKLIDYHVANGTSAIVSVGT
                     TGESATLSHDEHGDVVMMTLELADGRIPVIAGTGANATAEAISLTQRFNDSGIVGCLT
                     VTPYYNRPTQEGLFQHFKAIAEHTDLPQILYNVPSRTGCDMLPETVGRLAEIKNIIAI
                     KEATGNLTRVHQIKELVSDDFILLSGDDASALDFMQLGGHGVISVTANVAARDMADMC
                     KLAAEGQFAEARAINQRLMPLHNKLFVEPNPIPVKWACKALGLVATDTLRLPMTPITD
                     HGRDIVKAALQHAGLL"
     gene            20347..21381
                     /gene="bamC"
                     /locus_tag="OPV72_001287"
     CDS             20347..21381
                     /gene="bamC"
                     /locus_tag="OPV72_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamC"
                     /protein_id="HCR9913641.1"
                     /translation="MAYSVQKSRLAKVAGVSLVLLLAACSSDSRYKRQVSGDESYLDA
                     APLAELHAPAGMILPITTGDYVIPVTKGSGAVGKALDIRPPAQPLALVSGARTQFSGD
                     TATLLVENGRSSTLWPQVVSVIQAKNYPIEKRDDASQTLTTDWVSWNRLDEDEQYRGR
                     YQISVKPQGYQQAVTVKLVNLEQAGKPVADAASLQRYSTEMMNVISAGLDKTATDAAN
                     AAQNRSAATMDVQSAADDTGLPMLVVRGPFNLVWQRLPAALEKVGMKVTDSTRSQGSM
                     AVTYKPLSDSDWRDLGASDPGLASGDYKLQVGDLDNRSSLQFIDPKGHTLTQSQNDAL
                     VAVFQAAFNK"
     gene            21556..22269
                     /gene="purC"
                     /locus_tag="OPV72_001288"
     CDS             21556..22269
                     /gene="purC"
                     /locus_tag="OPV72_001288"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017458944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HCR9913642.1"
                     /translation="MQKQAELYRGKAKTVYSTENPDLLVLEFRNDTSAGDGARIEQFD
                     RKGMVNNKFNHFIMTKLAEAGIPTQMERLLSDTECLVKKLEMVPVECVVRNRAAGSLV
                     KRLGVEEGMELNPPIFDLFLKNDALHDPMVNSSYCETFGWVSQENLARMKELTYKAND
                     VLKKLFDDAGLILVDFKLEFGLYKGEVVLGDEFSPDGSRLWDKETLDKMDKDRFRQSL
                     GGLIEAYEAVAHRLGVKLD"
     gene            22401..23267
                     /locus_tag="OPV72_001289"
     CDS             22401..23267
                     /locus_tag="OPV72_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neutral zinc metallopeptidase"
                     /protein_id="HCR9913643.1"
                     /translation="MRWQGRRESNNVEDRRNRPGGPSLGGPGFRLPRGKGGIILLVVV
                     VVVAGYYGVDLTGLLTGQPVSQQQSTRSISPNDDEAAKFTSVILATTEDTWGQLFQKM
                     GRGYQQPKLVMYRGMTRTGCGAGQSVMGPFYCPADGTVYIDLSFYDVMKNKLGADGDF
                     AQGYVIAHEVGHHVQKLLGIEPKVRQLQQNASQTEVNRLSVRMELQADCFAGVWGHSM
                     QQQGVLEAGDLEEALNAAQAIGDDRLQQQGQGRVVPDSFTHGTSEQRYSWFKRGFDSG
                     DPAQCNTFGKNF"
     gene            23283..25298
                     /gene="tmcA"
                     /locus_tag="OPV72_001290"
     CDS             23283..25298
                     /gene="tmcA"
                     /locus_tag="OPV72_001290"
                     /EC_number="2.3.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA cytosine(34) acetyltransferase TmcA"
                     /protein_id="HCR9913644.1"
                     /translation="MSDIDALRALTSQMTQEGIRRLLVISGDAAWCRERAEAIRAVLP
                     GDWWVAPDAPAQPRCTPQALQTLLGREFRHAIFDAWQGFDAAAFAALSGTLQAGSWLL
                     LLMPPYETWESRPDTDSLRWSDCAQPIPTPQFAQHLKRTLSRDPQTLLWRQRQPFCWP
                     SYPSRERWRPATGEPQPEQAAILSRLREMPPGVATVIAPRGRGKSALAGQFISQMAGT
                     AIVTAPAKTATDILAAFAGERFCFMAPDALLASGARADWLVVDEAAAIPAPLLLQLVS
                     RFPRILLTTTVQGYEGTGRGFLLKFCARFPQLHRFTLRQPVRWAPECPLENIVSEALI
                     FDDEAFAQAPHGGIAISAFYQQAWGKTPALPRAVYQLLSGAHYRTSPLDLRRMMDAPG
                     QHFLQATANNRVAGALWLVEEGGLSAELSQAVWCGFRRPRGNLVAQSLAAHGSDPLAA
                     TLVGRRVSRIAVHPARQREGIGQQLIACACEQAAQCDYLSVSFGYTPELWRFWQRCGF
                     VLVRMGSHREASSGCYTAMALLPLSDAGQRLAQQEHRRLRRDADILTQWNGEAIPLAA
                     LREQALNDEDWRELVGFAFAHRPLLTSLGCLHRLLQYSALPLPALRGRLEEKASDAEL
                     CARLRISGRKALLALQRAQAAQALIALDAGRTQRLRDVMPGGGDHAG"
     gene            complement(25325..25525)
                     /locus_tag="OPV72_001291"
     CDS             complement(25325..25525)
                     /locus_tag="OPV72_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpfN family protein"
                     /protein_id="HCR9913645.1"
                     /translation="MDWLAKYWWILVLVFLVGVLLNVIKDLKRIDHKKFLANKPELPP
                     HRDFNDKWDDEDDWPKKDQPKK"
     gene            complement(25553..26680)
                     /gene="dapE"
                     /locus_tag="OPV72_001292"
     CDS             complement(25553..26680)
                     /gene="dapE"
                     /locus_tag="OPV72_001292"
                     /EC_number="3.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020078199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinyl-diaminopimelate desuccinylase"
                     /protein_id="HCR9913646.1"
                     /translation="MSCPVIELTQQLIRRPSLSPDDVGCQALMIERLRKIGFTIEHMD
                     FGDTQNFWAWRGRGETLAFAGHTDVVPAGDVDRWINPPFEPTIRDGMLFGRGAADMKG
                     SLAAMVVAAERFVAQHPHHRGRLAFLITSDEEASAKNGTVKVVEALMARNERLDYCLV
                     GEPSSTEIVGDVVKNGRRGSLTCNLTIHGVQGHVAYPHLADNPVHRAAPFLNELVAIE
                     WDRGNDFFPATSMQIANIQAGTGSNNVIPGELFVQFNFRFSTELTDEMIKERVHALLE
                     KHQLRYTVDWWLSGQPFLTARGKLVDAVVNAIEHYNEIKPQLLTTGGTSDGRFIARMG
                     AQVVELGPVNATIHKINECVNAADLQLLARMYQRIMEQLVA"
     gene            complement(26684..27040)
                     /locus_tag="OPV72_001293"
     CDS             complement(26684..27040)
                     /locus_tag="OPV72_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsC family reductase"
                     /protein_id="HCR9913647.1"
                     /translation="MITLYGIKNCDTIKKARRWLEEHGIDYRFHDYRVDGIDLPLLNT
                     FIAELGWQPLLNTRGTTWRKLDEGHRSGITDADSAAALMVEQPAIIKRPLLCAPGKPM
                     LLGFSESRYQQFFDEV"
BASE COUNT         6016 a         6960 c         7621 g         6728 t
ORIGIN      
        1 ataaaggctg caggagaaag gtaataattg acttaaatca aatgttactt ttgtttaata
       61 attacaatcg atgactatcg tgtgatgtat atcgcatcat caatttaaag tcaggtggga
      121 tgcctgtctg ttaacgcccc tttgggattg gggggttctg ctgagcatct atgaagctga
      181 ataaaactta tataaatatc agagataaat ggtggggact accgctcatt ctcccttcga
      241 ttttactacc tgttttaagt agcgcaaata cttatgcgct taccagcact ggaaatgtgg
      301 ttctttttta cctgccgtta gcttttatgc ttagtctgat gctctttttc ggctgggcag
      361 cactgccggg cattgtgctt gctatcttct ggcgcagata cccgcagaca gggctgtatg
      421 aaaccctttc tgtgacgatg cactttatca ttactatcgt gctaagctgg ggcggctatc
      481 gtgtcttttc cccccggcga aacaatgttt cccacggcga cgcccacctg ttgtttcaac
      541 gaatgttctg gcaggtattt tgttcagcga cattatttct ggtcatttac cagtttgccg
      601 cttttgttgg catgtacgaa agtaaagcca gcctgatggg ggtaatgccc tttaatatca
      661 acacgctgat taattaccag gcgttactgg tcggtaacct tgtcggcgtg ccattgtgct
      721 attttattat tcgtactctc cgcaatccgc tgcacctgcg ggggtattat cagcaattaa
      781 agctacagat tgatagcaag gccactaaaa aagagatcgt tatttggctg gctgtattga
      841 ctacactaat gtttatactg tgtatgccat tgacggataa tagctcaata tttagtacca
      901 actatacgct ttcgttatta ttgccggtca tgctgtgggg cgcgatgcgc tatggttata
      961 agtttatttc aattatctgg gccgtcgtgc taattacgtc gattcattat tatcagcgtt
     1021 atatgccctg gtattcaggt tatgatacgc aattagcgat tacctcttcg agctatctgg
     1081 ttttttcttt tattgttaat tatatgtctg tactggccac gcgtcagcgc gtagtgagtg
     1141 gtcgcgcacg gcggctggcc tatcttgacc cggttgtaca tcttcccaat ttacgtgcgt
     1201 taaaccgcgc gcttaaaaat gcaccctggt ctacgatctg ttttttacac gtgccgggtc
     1261 tggagctatt gggtaaaaat tatggcgtca tgctacgcat ccagtataag caaaagctct
     1321 ctcactggat tacgccgatg ttggcctcaa atgagtgcgt ctaccagatg tcagggcacg
     1381 acctggtgct gcgtcttaat acagaggcgc atcagcagcg tattgaagcg ctggataaac
     1441 atattaagca gtttcggttt atttgggatg gactgccgct acagccgcct gttggcgtga
     1501 gctactgctg cgtgcgttct ccggttagcc acctttatct gctgttgggc gaattaagca
     1561 ccagttccga tctttcgttg acgactaacg cgccggagga tttacagcgg cgcggcgcaa
     1621 tgcacctgca gcgcgatttg aagggcagaa ttgcgatgat gaatcgcctg caacaggcgt
     1681 tggagcacga tcattttttc ctgatggcgc agcctatttt cggtgttcgt ggggacgttt
     1741 accatgaaat tttactgcga ctcagggatg acaacggcga cgttatcaac ccggacaatt
     1801 ttttacccgt ggcgcatgag tttggtttgt cttccgctat cgatctctgg gtgattgaaa
     1861 acacgctacg gtttatggcg gccagccggg aatatatgcc cgcgcatcgt tttgccatta
     1921 atctgtcgcc aacatcggta tgccgcgccc gtttccctgc agaagttaag cagctgctta
     1981 cgcaatatca ggttgaaccc tggcaactgg tttttgaggt aacggaaagc aactctctca
     2041 ccaatgctga gcaggcgcag ttgacactgg gacagctaca gcagtttggc tgtcagatag
     2101 cgattgatga tttcggtact ggctacgcca gctatgcgcg gctgaaaaac gttgacgccg
     2161 atattcttaa aattgacggc agttttattc gcaatatagt gtcaaacagt ctcgattatc
     2221 agattgtggc ttctatttgt catttagcgc gaatgaaaaa tatgcaggtc gtcgcggagt
     2281 atatcgagag cgaagaaata cgaagcgtag tgctgtcgtt ggggatcgac tatcttcagg
     2341 gatatttaat tggcgagccg cagctattat ctgagattca gtaaaggcag acgccgcagc
     2401 gcggcgtctg atccacaatt tacgcggcga tctccggcga gctttcttcc tcaatattga
     2461 gacgccagcc agttaccgct tcccagtact gctgttcttt ttccagatca agcagtacca
     2521 gcgcattctg gctgaaccag tcatgcggaa aacataacgt ccagtggctg tcatcggtcg
     2581 ttagccgcag cgtcggcggt gtggtggtcg cctgccgctg gttgttcagt aatacgccca
     2641 gccgaagtag ctgaattaac ggcagatact gttttttctt aaacagcgta aagcggggca
     2701 tatcatccag ttttatggct ttacgatgat aacgcaccag cgtcgccatc atcatttgct
     2761 gctcctgatt aaagccgggc aaatcgctgt gttgcagaat ataagccgaa tggcgatgta
     2821 aaccgctgtg attaatattc agtccaacct catgcagcat tgccgcccag cggagcaacg
     2881 cttcaagctg cggatgcgcc agttttggct gctgggcctg ccactgctcg tacatctgca
     2941 tggtggtttc cagcacacgt ctggcctgtt ctctgtcaat gttgtattga ttggccagac
     3001 tttttgcggt acggctgcga acatcctgat ggcggaagcg gccttccatt tcatacagca
     3061 cgccttcgcg caacgcgccg tcggaaaggc gaagctcgcg gatagccaga gcatcaaaaa
     3121 cgccgcacag aatcgccagg cccggcacaa agaccgcttt tcgttcttca gacagacccg
     3181 gcaggctgag cgcattaaag gagcggtgct tcaacacttc tgacttcagt ttatcgaggc
     3241 gctccggcgt aatgaagcca tctttctcac ccagcgccag gagaacttca tgagcggcct
     3301 taatcgtacc ggaagcgccc atcgccacgt tccaaccctg aatacgatac tgccaggtta
     3361 aggtttccag tttttgcgct gccgccattc gggcgcgctg gaagttttct ttattgataa
     3421 cgccgccggg aaagtagagc tgcgcgaagc tcacgcagcc catacgacgg ctttcaacca
     3481 gcctgggttc gaagttttcg ccaataacca gctctgttga tccgccgccg atatcgatca
     3541 ccagcttgcg gcctttttcc ggctgcgtat gttctacgcc cataaaaatc aggcgcgctt
     3601 cttcgttacc ggaaataatc tctatcgggt agggaataac cttttccgcg cgtttgagaa
     3661 aatcagcggc attttgcgcc tgacgtaacg tatgggtgcc tacgatacaa acgctggaag
     3721 gggagaaacc ttgtaagcgt tcagcaaaca gcgacagaca gctaagcccc cgttccatgg
     3781 cttcttcgct gagtttgtta tctgcgccca gcccgtccgc cagatggacg cgctgtttta
     3841 agcgcccgat aatctgcatt gcgccgtcaa ccacgcgggc aatgaccata tgaaagctgt
     3901 ttgagccgag atcgaccgca gcgaactcct gcgggcgagg ggatttatcg taaattggca
     3961 tagcgttagt ctggttgctc gagtgatttg atgtagtcat aaattgccag ctgcgcctga
     4021 actttgcggc gattgccgcg cggtacgtag cggttgctga gttctttatc gataaaacgc
     4081 gcttttaccg tgtcgctaaa cagaatgtca atgatatcca ggacgcgttg tttaagccgc
     4141 gggtcgagga taggcgtagc gacttcgata cggtagtcaa tattacgcgt catccagtca
     4201 gctgaagaga gccaaacttg cttatcaccg ccgttttcga aaatataaac ccgatcgtgt
     4261 tccagatagc gatccacgat gctaatcgcg cgaatattat cgctaatgcc ttccagttgc
     4321 ggaataagag aacacatacc gcgcaccagc agattgacct ggacgcccga acccgacgcg
     4381 gcgtatagcc tgtcgaccaa ccctttatcg accaggttgt taagctttaa ggtaatccct
     4441 gacggtaagc cttgctgggc attggcaatt tcacgatcga tcatctcata cagcagacgc
     4501 cgtgagtttt gtggagaaac catcaaataa tcgaaagtga ccgggcgata ggggttttca
     4561 ataaaattaa agacccggcg cacttcattg gtaatgcgcg catcggcggt cagcagcgaa
     4621 taatcggtat acagccgcgc cgttttttcg ttgaagttac cggtgccgat atgcgcataa
     4681 cgcaccacgt catcgccctc ttttcgtgag atgagaaaga gtttggcgtg aattttcagc
     4741 ccgggcgcag agaaaataac atggacgccc gcttcggtta accgcttggc ccagtgaata
     4801 ttcgcctctt catcgaagcg cgcctgcaac tccaccacca cggtgacttt tttgccgtta
     4861 tgggcggcat ggatcatcga gtcaataatg cgcgagtctt tcgctacgcg ataaatattg
     4921 attttgatcg ccagcacgct tgggtcaaac gacgcctggc gcagcagttc cagtacatgc
     4981 tcgaaggtat ggtacggata atagagcagc acatcacgtt cacgaatcgc gtcgaaaccg
     5041 ttacgaaact tctctttatc aaaccaaaga tggcgtaacc gcggtaacgg tttattgacc
     5101 aggttggctt taccgacatt cggaaaatta ataaagtctt taaaattgtg gtagcgcccg
     5161 ccgggtacga ttgagtcata ccgggagatc gtcagttttt cccgcagcac gtcgaccagc
     5221 gcggcgggca tatcgcgttg atagacaaag cgcacaggtt cagcggtcag gcgctgcttc
     5281 aggctggagg acatcagctc catcagactg gattccatct catgcaccag gtcatattcg
     5341 gcatcgcggg tcattttcat cgaataggca ttgagcgcgt catagtcgaa gaacccttta
     5401 aaaatgtcat ccaggcagta gcgcagaata ttatccagta ggatcatcgg cttgcgtctg
     5461 cgcggtgtct ccggcggcag attaacgaag cgtgggactt tgtcggacgg tatctccagc
     5521 agcgcatagt tgatggtgtc gccgcggata atctccaccg ccagataggt gtaatcatct
     5581 tttaaaaact gaacaagatc cgtctcccgg ttaatgagaa tcggggtaat atgctggcgc
     5641 aaatagtgct taaaatagtg gcgcaaccag ctttgttggt tcaccgagag ctgacgctcg
     5701 ttgatcagaa agatttgatt acgcgccatt tccagcagta attcgttgta caggccgtcg
     5761 aacccctggt ctgctttcaa cacgcgggac tgaattttgc ctaacaaatg gcgtgaatga
     5821 gaatttgaac cctgttcttc gctgataata atgcgtcgtt tcagttcagc gaaacgcact
     5881 ttgtagaact cgtcgaggtt attagaatag attcccagga accgcatccg ctcaatcaac
     5941 gggttggatt tatccgctgc ttcctgtaac acgcgttcgt taaatgctaa ccagctcagc
     6001 tctttctcga tatatagctt ttcctgaccc attactacct atactccgtt ttattcacgg
     6061 gacactgcct gataattatg gcgagcatta cgcgttaatg tccaacagcg tcagaaaaat
     6121 atgacaataa actgatagca taaaggaagg gaaaagagta ggccggatag gcatttatgc
     6181 cgccatccgg caagcagacg cagccctggc cgatgacata ttattcgtca gacgcataac
     6241 cttgcggcgg cagacgacgc ccgtccagcc aggcggcgtt atcgcgcatc tttagacgcc
     6301 cctgcgcaaa ccagccaatc accagcggat aaatcgcatg ttcctgagtt tgtacgcgtg
     6361 cggtgatatc atcttcgctg tcgttggcaa aaaccggcac cttcgcctgg agaatgaccg
     6421 ggccgccgtc gagttcgtct gtcacgaaat gcaccgaggt accgtgctcc tcatcgccgt
     6481 tttccagcgc ctggcgatgg gtatgcaacc ccggatattt tggcagcagg gaagggtgaa
     6541 tgttcagcag acgcccgtag taatgcgcga caaacatcgg actcagaata cgcataaaac
     6601 cggccagcac gaccacatcg ggcgcatacg cgtctatctt gcgaatcaac tcgcgatcga
     6661 aggcgtcgcg gctgtcaaac cgatcggcag tcagcgcttg cgccggaatg ccggcttctc
     6721 tggcgcgttc aaggccgaac gcgtcggcct tattgctgaa tactgccctg agggtgcctt
     6781 taattttctt cgcttcgcag gcatcgataa tcgcctgtaa attgcttcca ttgccggaaa
     6841 tcagcaccac aatattcatt attcaataac cacacgctgt tcggaatcag aggctttgat
     6901 gataccgatt ttccatgcgt tttcaccttt ctcgtttagc agagcaagcg ctttgtccgc
     6961 ttccggagca gagagcgcaa tcaccatgcc gacgccgcag ttaaaggcac ggtacatttc
     7021 atgtcggctg acattaccgg cggttcgcag ccaggtaaag atggcgggcc actgccagga
     7081 cgactcatta attaccgcct gggtattctc cggcagaacg cgcggaatat tttcccaaaa
     7141 gccgccgccg gtgaggtggg cgatagcgtg tacatcgatg ttttcaatca gttccagaac
     7201 cgattttacg tagatacggg tcggttcaag cagatgatcg gccagcggtt tcccttccag
     7261 cagagtggtc tgtggatcgc agccgctaac gtcaataatt ttccgcacca gcgaatatcc
     7321 attcgagtgc gggccgctgg agccgagcgc aatcagcacg tcgccttcgg caacccggga
     7381 gccatcgatg atttctgatt tttcgactac gccgacgcag aaacccgcca catcgtaatc
     7441 ttcgccgtga tacatgcccg gcatttccgc cgtctcgccg ccgaccagcg cgcagccgga
     7501 ttgcaggcag ccttcggcaa taccgttgat cacgctggcg gcggtatcga catccagttt
     7561 accggtggca tagtaatcga ggaaaaacag cggttccgcg ccctgaacga ccagatcgtt
     7621 tacgcacatc gccaccagat caataccgat agcgtcgtga cgctttaagt ccatcgccag
     7681 gcgaagtttg gtgcctacgc cgtcagtgcc ggaaaccagt accggttcac gatatttttg
     7741 cggcaacgcg cacagcgcac cgaaaccgcc cagaccgccc ataacctccg agcggcgagt
     7801 tttcttcact acgcctttga ttcgatcaac cagagcgtta cccgcatcaa tatcgacgcc
     7861 ggcatcttta tagctaagag aggtcttatc ggtcactgcc tggttcccca cgttttttct
     7921 tgcggtaaaa gttaaattcg gcgcaattct aacagggaaa gcaaacgttt gcgagcgtgg
     7981 tctgcgccct ggttatccgg gcgatttttt ggcatggttt cggtcgctgc ttgaaaattt
     8041 ccctgttggt aaaaaagaaa aggatatcca gcacttggtt tacgacaggt ggtcgggaca
     8101 ggtcattcac ccttaaaatt gctaagattc aatcggttgt tagcttttat cgccagtttc
     8161 aacgtgagtg atttatactc acttttccgc tatcagcgct tttggttgat ccaggtcaag
     8221 catacattgt gttgcgtcag agaggaaaag cggtataatc cggcgatttt ttttgtggtt
     8281 gccagtcatc tgaggatagg agaagagtat gaagatcgtg gaagtcaaac acccactcgt
     8341 caaacacaag ctgggtctga tgcgtgaaaa cgacattagc actaaacgct ttcgtgaact
     8401 cgcctcagaa gtaggcagcc tgctgacgta tgaagcgaca gccgacctgg aaacggaaaa
     8461 agtcaccatc gaaggctgga atggcccggt ggaaatcgac cagatcaaag gtaaaaaaat
     8521 taccgttgtg ccgattctgc gcgcggggtt gggcatgatg gaaggcgttc tggaaaatgt
     8581 accgagcgcg cgtatcagcg tagtcgggat gtaccgtaac gaagagacgc tcgagccagt
     8641 accttatttc cagaaactgg tatcgaacat tgatgagcgc atggcgctga tcgtcgaccc
     8701 gatgctggcg accggcggtt ctgtcatcgc gaccatcgac ctgctgaaaa aagcaggctg
     8761 tagcagcatt aaggtgctgg tgctggtcgc cgcgccggaa ggcattgcgg cgctggaaaa
     8821 agcgcacccg gacgttgaac tgtacaccgc ctctatcgat caggggctta acgagcacgg
     8881 atacattatt ccggggcttg gcgatgccgg cgataagatt tttggtacca aataagtgaa
     8941 taaataatta aaagccgact ttaagagtcg gctttttttt gaataaaacc actaataaca
     9001 aacacactta gaggaaaaca ctatgacgcg ccgtgctatc ggggtgagtg aaagaccgcc
     9061 gcttttacag acaatcccgc ttagtttaca gcaccttttc gccatgtttg gcgcgaccgt
     9121 gctggtgcca gttctgtttc atatcaatcc cgcgacggtg ctgctgttta acggtatcgg
     9181 aacgttgctg tatctcttta tctgcaaagg taaaattcct gcctacctcg gatcgagctt
     9241 tgcctttatt tccccggtat tactgttgtt gccgctgggt tatgaagtgg cgctgggcgg
     9301 ttttattatg tgcggcgtgt tgttctgtct ggtctctttc atcgttaaaa aagcgggcac
     9361 cggctggctg gatgtgatgt tcccgcctgc ggcaatgggc gcaatcgttg ccgtcatcgg
     9421 tctggagctg gctggcgtcg cggcggggat ggccggattg ctgcctgcgc aagggcagtc
     9481 gccggacacg aaaacaatta ttatctccat ggtcacgctg gcggtgacgg tgttcggctc
     9541 cgtactgttt cgcggtttcc tggcgatcat tccgattttg atcggcgtgc tggcgggcta
     9601 tgcgctgtca ttcgcgctgg gggtggtcga taccacgccg attgcccagg cgcactggtt
     9661 tgcgctgccg accttctata cgccgcgttt tgaatggttt gcgatcctga cgattctgcc
     9721 cgcggcgttg gtcgtgatcg ccgagcatgt cggtcatctg gtggtgacgg cgaatatcgt
     9781 caaaaaagat ttagtgcgcg atcccggttt gcaccgctcg atgttcgcta acggactgtc
     9841 gacgatcatt tccggtttct tcggctccac gccgaatacc acctatgggg aaaatattgg
     9901 cgtcatggcg atcacccgcg tttacagtac ctgggttatc ggcggcgcgg cgattttcgc
     9961 cattctgctt tcctgcgtcg gcaaactggc ggcggcgatt cagattatcc cgttacccgt
    10021 gatgggcggc gtctcgctgc tgttgtacgg cgtcatcggc gcgtcgggga ttcgcgtctt
    10081 gatcgaatcg aaagtcgact acaacaaagc gcaaaacctg atcctcacct cggtgatttt
    10141 gatcatcggc gttagcggcg cgaaagtgca tatcggcgcg gcagaattga aagggatggc
    10201 gctggcgacc atcgtcggga ttggcctgag cctgattttt aaactgatta gcctgttgcg
    10261 tccggaagaa gtggtactgg aggcaaatga tgcggagtct ccgcatcagt aacgggttgc
    10321 cgggcagcga tgctgcccgg ttctatctca cgggaattat gtggtaaact cagcgcgatt
    10381 ttatgtcatc ctgggttgag gtatctctga acacaccggc acagctctct ttgccacttt
    10441 atcttcctga cgacgaaact ttcgcaagtt tctggccggg ggataacgcc tctctactgg
    10501 ccgcgttaca aaacgtgttg cgccaggaac atagtggata tatctacctt tgggcgcgtg
    10561 aaggcgcggg ccgcagccat ttgctgcacg ccgcctgcgc tgaactgtcg cagcgtggag
    10621 atgcggtagg ctacgtcccg ctcgataaac gcacctggtt cgtgccggaa gtgctcgacg
    10681 gtatggaaca cctctcgctg gtgtgtattg ataacattga gtgcgtcgct ggcgatgaac
    10741 tgtgggagat ggccatcttt gatctctata accgcattct ggagtccggt aagacgcggt
    10801 tattgatcac cggcgatcgt ccgccaagac agttaaatct gggcttaccc gatctcgctt
    10861 cccgtctgga ctgggggcaa atctataaac tccagcctct ttccgatgaa gacaaacttc
    10921 aggcgctaca gttgcgtgcc cgattacggg ggtttgaact gccggaagat gtcggacggt
    10981 ttttactcaa acgtcttgat cgcgaaatgc gcacgctgtt tatgacgctg gatcagctcg
    11041 atcatgcgtc gatcactgcc cagcgaaaac tgacgatccc gtttgtcaaa gagatcctga
    11101 aactgtaata cgccgcgacg gcggcgttta acggttaacc gaggatgtcc agcacctgct
    11161 caggcggtcg gccaatacgc gcctgaccat ttgccactac aatggggcgc tccatcagtt
    11221 tagggtgttc aaccagcgcc tggattaacg cctcttcact tagctggcta tccgccaggt
    11281 gaagcgtctt atagagatct tctttctggc gcatcagttc gcgcgcgctg gacatgccca
    11341 acatacgcag cagttcccgc acggtggcgg catcggcggg cgtatccaga taaagcacca
    11401 cttccggttc cacgccgtta gatttcagca ggttcagcgt gtcgcggctc ttcgagcagc
    11461 gcgggttatg gtagatttta atcgtgtcgg tcatgagttc tccttgtgac gccatccggc
    11521 taataaacgg cgattacatt ttcgtgtatg gcttgaagcg ttcctgtaac tggcgcaact
    11581 ggtcgatacg cgcatcgtaa cgcgcctgtt gctgactacc cagttttgcc tgggcgctgg
    11641 cgctgctgag cagtgaaatt gcctgatcca gtcgtcccgc cagcgcataa ctttcagcgc
    11701 gtgccgccag ctcctgatcg cggttgttca gcgcggcttc ggcctgagca agcagatccc
    11761 agccgttacc gtcatcttta tggctaaagg tgtagcgatt cagaatggtt tccgccgctt
    11821 tcggctggcc tccctggagg tacgcattgg cgaggtttaa ctgcagcaca ggattaacgc
    11881 gcagatcgcg ggcatttttc aggcgattaa tcgcgtcgtt ggctcttttc tgccccaggt
    11941 caatatcggt ggcgaggtca agataccagg cattgttcgg ctctgcgctt aatagcggct
    12001 gcaacgtttt gcgcgcttca tcgtacttgc tcgcttccat cgcctgcaac gcccggccat
    12061 attgcgccgc atgttgctga cgcacgttgc ctttagacca ctgatccagc aggtcgctgg
    12121 tgagctggtt acgtccggaa ttgtacattc ccagggcgcg cgctttggcg aaataaaagt
    12181 cggcggaaga ttgcaccacg accgggcgca tctggttggc acggttgcgg gcatccgcaa
    12241 ggcggctttc cggtaagggg tgagtgagca aaatttcagg cggtcgcgtg gagtaacgcg
    12301 cctggtcgag cagtttttcg aggaaagagg gcatcgcctg tgggtcaaat ccggcgcgtt
    12361 gcagtacctg aataccaata cggtcggcct cttgctcatt ttgctgggtg aaacttatca
    12421 ttccctggcg cgttcccgcc agagtaccgg ttagcgccgc cataccggcc tgtgggctgg
    12481 ccatggccag caaaatggaa cccagcgcgc ccacccaggt aagcggcgcg ctgcgctttt
    12541 gatcttccat cgcgcgcgcc agatggcgct gcgtaacgtg ggaaatttca tgcgccatga
    12601 ctgaagctag ctggctttcg ttatccgcgt agcgaaaaag cgccgagtgc agcaccacat
    12661 tgccgccaaa gaacgcgaac gcgttgattt cgtcattatt gatcaagaaa aaatggaagg
    12721 gcgttttgac ggagtctgcg tgcgagacca gacgcatccc cagcgcgtta atgtattgca
    12781 ccagcagcgg atcgttgatt aacggcgcgc tgccgcgtag ctggcgcaca taaaagtcgc
    12841 ccatttgcat ctcttgtcca atagaaagcg tgcttcctgc cgaggttccc atatcgggca
    12901 gcgtgtcggc agggtcggca aatgcgggcg cgacctgacc gagagccaat gctgcaatga
    12961 gggttgccac caggtttttt ttcaactgcc tgaacataac ctctatcctg ttgttttgag
    13021 atagcccttt gaccaacgtc gtgaaatatc gttccacgct ccgacacttc ataagtgtaa
    13081 ctgtgatgag cacagactca ctattttagt ttcctgaatc aacgataaaa agcgaagtct
    13141 tttttgtgac atttcgatac aattcggcat cacaatcccg cagttgagtt ctgggaaggg
    13201 ttttatgctc gaaatgttaa tgcaatggta tcgccgtcgc ttcagcgatc cggaggcgat
    13261 tgccttgctg gtcattctgg tggctggttt tagcatcctc tttttcttta gcggcctgtt
    13321 agcgccgctg ctggtcgcta tcgtactggc ctacctgctg gagtggccga cggcgcgcct
    13381 gcaggcgatt ggctgttccc ggcgctgggc agcctccatt gtccttatcc tctttgtcgg
    13441 cattctgtta ttaatggcgt ttgtggtgat gccgattgcc tggcagcagg gtatttacct
    13501 gattcgtgat atgcctggta tgctgaataa actgtccgat tttgccgcga ccttgccgcg
    13561 acgctatccg gcgctgatgg atgcgggcat tattgatgcg atggcggaaa acatgcgtac
    13621 ccggatgctt aacatgggcg attcggtggt gaaatattcg ctggcttcgt tagtcgggct
    13681 actgacgctg gcggtatatc tggtgctggt gccgctgatg gtctttttcc tggtaaaaga
    13741 taaagagcag atgctgaatg ccgtgcgccg cgtgctgccg cgtaatcgcg ggctggcggg
    13801 gcaggtgtgg aatgagatga atcagcagat caccaactat atccgcggaa aagtgctgga
    13861 gatggtagtg gtgggcgtgg cgacctggct gggctttttg ttgtttggcc tcaactattc
    13921 gctactgttg gcggtactgg tgggcttttc ggtcctgatc ccctatatcg gcgcctttgt
    13981 ggtgacaatt ccggtggtgg gcgtcgcgct gtttcagttt ggtctgggga cggaattctg
    14041 gagctgtttt gccgtttatc tgattattca ggcgctggat ggcaatttgc tggtaccggt
    14101 acttttctcc gaagcggtga atttgcatcc gctggtgatt attctgtcag tggtgatttt
    14161 cggcggtctg tggggattct ggggggtatt tttcgccatt ccattggcga cgctgattaa
    14221 agccgttgtc catgcctggc cggatggtca ggtgacggat gcctcatcct gagcggtctg
    14281 tacaaaagtt gtaaagcgtg aacgacatca tagtgccctg ccgccatttt gcgcacgcct
    14341 gatgagggtc aagcgcttag aaagccgctc ttttttttaa tgccgcaccg tgttgcggca
    14401 tttttattgt cggaacctac aaaattctcg ctgtaaagcc gccaaaattt ggtgacttag
    14461 cctaagcatt cttctgagaa attcgttaat aagtgacatc attgatgcga gattgctttt
    14521 ttaatgtgaa gcgataacga aacagggaat gagtgtgttg agaaaacatt acttgaaagg
    14581 gtataccgcg cggcaaattg tacagcgagc catgaaaatt attccttact cggtaaacgt
    14641 catggatgag catggcgtca ttatcgcgtc tggcgaacct tcgcggcttc gccagcgtca
    14701 cgaaggggcc attctggcgc tgaaggaaaa ccgtattgta gaaattgatt ccgctaccgc
    14761 caatcagctt aaaggcgtgc gatccggcat taatcttccc atctcttttc atgaacagct
    14821 tatcggcgtg gtcggcatta ccggcgaacc ggaggaggtt cgcgcgtatg ccgagctggt
    14881 taaaatggcg gcggagctgg tgatcgagca tatggtgctg atcgaacagt gacaatggga
    14941 taaacgctat cgcgaagagc tgatcaacca attgattttg cgagaaaatt caacagagtc
    15001 gttgcgctcc atggcggcct atctgggcat tgatctggcg gttcccagag tggtgctgat
    15061 tattgaactt tcccagccgg atcgcgaagc gctgcgcaat gtaatggatt atttcgagaa
    15121 tcacgcgcgc aaccatttgg tgacgtttac cgaatttaat gaattaatca ttattaagcc
    15181 tatcacgtta aaagagggaa agtggaatac ccgccaggaa atgggcgaat tgcagatttt
    15241 taaatcatgg gctgcatcat cgggctttag ccgtattttg gttgggggct attttgccgg
    15301 cgagacggga ttgcaccgat ctttgctcac agcgagagcc acgcaggcga tggcgaaaag
    15361 acaaaagctg cgcagccagt acatttttta tcatgaccac gcgcttcccg cgctgctaag
    15421 cgggctgtct gaaagttggc aagtgcagga gttatcgcgt ctgtggctgc aactggtgca
    15481 acatgacgcg aaaggcgtat tgcaacagac gctgcggact tggtttgaac ataattgtga
    15541 cctgacgcaa acggccaaag cattgcatat tcatgtgaat acattgcgct atcgcttaca
    15601 gcgctgtgag gatattacgc acataaaaat caacgagtta aaaagtacgc tttggcttta
    15661 tatcggtatg gagcttcagg ccgaatctgt atcgtccgac aagttaccgc tgcctggtcg
    15721 aatcgaaatt tgttgaaagc tccagcggat ttttaggcgg ttttttccat actgcgcgct
    15781 ccatgttaaa ggaggcgcag tatatgacgt cgatatccac cttgggagcc attgccgcat
    15841 tggttgtggc catcgtatta attttaagaa aagtgtcgcc agcctacggc atgatggcgg
    15901 gcgcgctggt cggcggtttg attggcggcg ccgatcttct gcaaaccgtg tcgctgatgg
    15961 tgtcaggcgc gcagggcatc gttaatgccg tattgcgtat tctggccgca ggcgtactgg
    16021 cgggcgtatt aattgagtcc ggggcggcga atacgattgc tgagacgatt gtccgcaaag
    16081 tgggggaaac ccgggcatta ttggcattag ccattgccac actatgtttg accgccgtcg
    16141 gcgtatttat tgatgtggcg gtgattaccg tcgcgccgat tgcgctgtcg attgcgcgta
    16201 atgcaggcct gtcaaaaagc gctattctgc tggcgatggt cggcggcggc aaagcgggta
    16261 acgtgatgtc acctaacccg aacgctattg ccgcctccga tgcgtttcat gttcctctta
    16321 cctctattat gctggcgggc gtggttccgg gcatcgttgg gcttattatc gcctatctgt
    16381 tagcgaaacg gctgaataat aaaggcgcgg gcgtcgccga tcatgaagtg actcaccatg
    16441 atgactctgt cgccaggccc ggttttctgg tggcgattag cgcgccgctg gtcgctattt
    16501 tcctgctttc tctccgtccg tttgtcggca tttccattga cccgttaatt gccctgcccg
    16561 tagggggatt ggtcggtctg ctgttgatgg gacgcgcgcg ccactgtaac cagtacatgg
    16621 tcgccggtct gatgcgtatg gcgcctgtcg ctattatgtt gctgggaacc ggtacgctgg
    16681 ccggcattat cgctaattcc gaacttaaag atgtcctgat tcatggcctc accgcttcgg
    16741 gattgccgtc ctggctgctg gcgcccgtgt ctggcgccat gatgtcaatg gcgacggcct
    16801 caaccacagc gggaacggcg gtggcgtccg gcgttttctc tcccacgtta cttgaacttg
    16861 gcgtttccgc cctggcggga gccgctatga tccatgcggg cgccacggtg ctggaccatc
    16921 tgccgcatgg cagctttttc cacgcgacgg gcggcagcgt caatatgcaa attcatgaac
    16981 gtttaaagct aatgccgtat gaaacgctgg tggggttagc cattaccttt atttctactc
    17041 tgatgttcgg tttctttggt tttgcaggat aatccctatg aaaattgtta ttgctcctga
    17101 ttcatttaaa gaaagtttgt ccgcaatggc ggtcgctgag gcgatagaaa aggggttccg
    17161 cgaaatttat cctgacgccg actacgttaa ggtgcccatg gcggatggcg gggaaggaac
    17221 cgtgcaatca atggtggaag ctagcggcgg gcgttatgtt gaccagtggg tacaaggccc
    17281 gcttgggcaa ccggtaaccg cgcgttgggg aatgctgggc gatagcgata ccgccgtgat
    17341 tgaaatggcg gcggcatccg ggctgcatca cgtttcgcct gaattgcgta acccgcttaa
    17401 tactaccagc tacggcaccg gcgagttaat cgtcgcggcg ctggagcgtg gcgtaaagcg
    17461 tattattctg ggaattggcg gcagtgcgac gaatgacggc ggcgcgggga tgatgcaggc
    17521 gcttggcgtt atattgcgcg ataaacaggg gcgctcgctt tctccgggcg gcgaggcgct
    17581 ggcggcgctg gcgtctatcg atttgtccgg ttgtcaccca ttgctgcgta aggtatcgat
    17641 aaccgtggcg tgtgatgtca acaatccgct gtgtggtccc cagggcgcat cggccatctt
    17701 tggcccacaa aaaggggcga cagcggaaat ggtgaactcc ctggacgcgg cgctggaaaa
    17761 ctggggccga catatttatc aggcaacggg acgtgaggtg attaacgctc ccggcgcggg
    17821 cgcggcaggc ggaatgggcg ccgcgctttt agggttgctc aatgcggaat tacgcgccgg
    17881 cgtagagatt gtcgtggaaa cgctacagct tgagcaggcg gttaaagatg ccgatctggt
    17941 gattaccgga gaagggcggc tggacagcca aagtatttgc ggcaagacgc cgattggcgt
    18001 cgccagagtg gcgaagcggc atcataaacc ggttatcgcg ctcgccggtg ggctgcaaca
    18061 cgatcatcac gttgtgtatc agcagggtat cgatgcggcg ctatcgattt tgtcgcatat
    18121 cgttacgctg ccggaagcct tacacgaggc ggaatataac ctgagcctgt cggcgcgcaa
    18181 tgtggcggcg atatggcgtc tggcgcggca agcctgacgg cgcattccct ttccaggccg
    18241 cacatcagcg cggcctgagg cttttacgcg ttttctttca gccagttcag caccacatca
    18301 tggtgattgc tggttttaaa atcattaaag acgtgctcaa tcttaccatc agcgtcaatc
    18361 aaaaagctga tgcggtgaat gccgtcatac gttttgccca taaacgactt ttcgccccag
    18421 acgccaaact gttcacacac ctgatggttt tcatcggaca aaagggtaaa gttcagcagc
    18481 tctttttcag cgaaacggga gagtttttca ggtttatcgg tgctgatgcc cagcacgtcc
    18541 acgcctgctt ttttaagctc gtccatgtta tcgcgtaagc cgcaggcctg cacggtacag
    18601 ccgggtgtca tggcttttgg gtagaaataa accagaacgc gctgcccctg gaagtcggtc
    18661 aaatttactt gttccccgtc ttgatccggc aagctaaatt tcggtgcgat atcaccggct
    18721 ttcagtggat tcattactta actccatcct gttcatcatg ttgtgagtaa ttgacgacgt
    18781 ttatactgcc ttgcgcattg agttctgtac atagtgcttt aaaggcttgc tcaatatttg
    18841 cggaattttg cgacgccggg ctatgtgcgg tgatttgaat aaataattgc gcagctttat
    18901 catcttcagc cggctgcgtg cgggagacca gctccgcaat attcatttca tgactattaa
    18961 acagcgcggt gaatcgctca attaaatgcg gggagtcggc gacctcaacc tgaacccata
    19021 ccgtcgcggg cattgccggg cgggggcggt cggacgtccg tttcatcaca atcagcagat
    19081 ccagctccgc gccttttaac ggcaatgtcg attcaatcaa ggtaatcgcg ttccacgtgc
    19141 cggacaacag cataataaac gtgaattcat cgcccagcat cgccagtcgg ctgtcttcga
    19201 tattacagcc gcaactgctg acatggcgag taatggtatt cacaataccg ggcctgtcgg
    19261 cgcccagcgc agtgataacc aaatagtgtt gtgatgacgg tgtcaaacca gttattcctt
    19321 tgagcggtga ggtaatctta aggaaaccat aaaaaaaacc tgcatacaac aatcagaacg
    19381 gctttggtcg cttgctttta ttgtcatacc aaacgtacca ttgagggact tgtttgcaca
    19441 gaggatggcc catgttcacg ggaagtattg tcgcgcttgt tacgccgatg gatgagaaag
    19501 gtaacgtcag taggtcttgc ctgaaaaaac tcattgatta tcatgtcgcc aacggtacct
    19561 cggcgattgt ttcggttggc accaccggcg agtctgccac gctaagccat gatgaacatg
    19621 gcgatgtcgt gatgatgacg ctggaactgg ctgacggacg tattccggtt atcgctggca
    19681 cgggcgcaaa cgcgaccgcg gaagcgatta gcctgacgca gcgttttaac gatagcggca
    19741 ttgttggctg cctgacggta acgccgtact acaatcgccc cacgcaggaa ggtttgttcc
    19801 agcatttcaa agccatcgcg gaacacactg acttgccgca aattctgtat aatgtgccgt
    19861 cccgtaccgg ttgcgacatg ttgccggaaa ccgtgggtcg tctggcggaa ataaaaaata
    19921 ttatcgctat caaagaggcg acagggaact taacccgcgt tcaccagatc aaagagctgg
    19981 tttcagacga ttttattctg cttagcggcg atgacgcgtc cgcgctggac tttatgcaac
    20041 tgggtggtca tggcgtgatt tccgttactg ctaacgtagc ggcgcgcgat atggctgaca
    20101 tgtgcaaact ggcggcggaa gggcaatttg ccgaggcgcg cgctatcaac cagcgtctga
    20161 tgccgttaca caacaaacta tttgtcgaac ccaatcctat cccggtgaaa tgggcatgta
    20221 aggcattggg tcttgtggcg accgacacgc tgcgcctgcc aatgacgcct atcaccgacc
    20281 atggtcgtga catcgtcaaa gcagcgcttc agcatgctgg cctgctgtaa agtttaggga
    20341 gatttgatgg cttactcagt acaaaagtcg cgcctggcga aggttgcggg tgtttcgctt
    20401 gttttgctgc tcgctgcctg tagttccgat tcgcgctaca agcgccaggt aagcggcgat
    20461 gaatcctatc tggatgccgc gccgcttgct gaacttcacg ccccggcagg aatgattctg
    20521 ccgataacga ccggcgacta cgttattccg gtcacgaagg ggagcggcgc ggttggtaag
    20581 gcgttggata tccgtccgcc ggcgcagccg ttagcgttag tgagcggcgc gcgtacccag
    20641 ttctctggcg ataccgctac gctattggtg gaaaatggcc gtagcagcac gctgtggccg
    20701 caagtcgtca gcgtgattca ggcgaaaaat tatccgattg aaaaacgtga cgatgccagc
    20761 cagaccctga cgaccgattg ggtgagctgg aaccgcctgg atgaagacga acagtatcgc
    20821 ggacgttatc aaatctcggt gaagccgcag ggctatcagc aggcggtaac ggtaaaactg
    20881 gttaatctgg aacaggctgg caagccggtc gctgatgcgg cgtcgctgca gcgctatagc
    20941 actgaaatga tgaacgtcat ttccgccggt ctggataaga ccgctacgga tgcggcaaat
    21001 gccgcgcaga accgttccgc cgcaacgatg gatgtgcaga gcgccgctga tgataccggt
    21061 ttacctatgc tggtcgttcg cggtccgttc aacctcgtgt ggcagcgtct cccggccgcg
    21121 ctggaaaaag tgggcatgaa agtcaccgac agcactcgct ctcagggcag catggcggta
    21181 acgtacaaac cgttgtctga cagcgactgg cgggatctgg gcgctagcga cccgggcctg
    21241 gcatccggag actataaatt gcaggtcggc gatttagata accgcagcag cttgcagttt
    21301 atcgatccta aggggcatac tctgacgcaa agccagaacg acgcgctggt tgccgtcttc
    21361 caggctgcgt tcaacaagta atttaacagg gctggagcaa tccggccctt ttttctgata
    21421 agatacgcaa acgtgtgcgt cggtacaaaa acgcgattta accgctattt cgcaccacaa
    21481 ttacaggccg gcgtctctgg caggcgtagc aggaaatgaa tacttatcgt taattcacac
    21541 ccaggagtgt taaagatgca aaagcaagct gagttgtatc gtggtaaagc gaaaaccgta
    21601 tacagcacgg aaaacccgga cctgttggtg ctcgaattcc gcaatgatac gtcagcaggg
    21661 gatggcgcgc gcattgaaca gtttgatcgc aaaggcatgg taaataacaa attcaaccat
    21721 ttcattatga ccaaactggc cgaggcgggc atcccgaccc agatggaacg tttgctgtct
    21781 gataccgagt gtctggtgaa gaagctggag atggtgccgg ttgaatgtgt ggtgcgcaac
    21841 cgtgcggcag ggtcgctggt caagcgtctg ggcgtggaag aaggcatgga gcttaacccg
    21901 ccgatcttcg atctgttcct gaaaaacgac gcgctgcacg acccgatggt gaatagttcc
    21961 tactgtgaaa ctttcgggtg ggtaagccag gaaaatctgg cgcgtatgaa agagctaacc
    22021 tacaaagcca acgacgtact aaaaaaactg tttgatgacg cgggtcttat cctggtggat
    22081 ttcaaactgg agtttggcct gtataaaggc gaagtggtgc tgggcgatga gttttcaccg
    22141 gacggtagcc gcctgtggga taaagagacg ctggacaaaa tggacaaaga ccgcttccgc
    22201 cagagcctgg gcggtctgat tgaagcctat gaagccgttg cgcatcgcct gggcgtgaaa
    22261 ttagattaat tccgcttctg accggggggg caaccgctct ccggtatcat cctttcctca
    22321 ttctgatagc gtttacctgt ggtaatcctg cgcctgaccg cctacgatca tctgtataac
    22381 aaagagagaa tgaggtgatt atgcgctggc aagggcgtcg tgaaagtaac aatgtagagg
    22441 acagacgtaa tcggccaggc ggcccctcgc tgggtggccc tggctttcgt cttccgcgcg
    22501 ggaaaggcgg catcattctg ttggtggtgg tggtggtggt cgcagggtac tatggggtgg
    22561 atttaaccgg tctgttgact ggtcagccgg tttcgcagca gcagtcgacg cgttcgataa
    22621 gccccaatga tgatgaagcg gcaaaattta cctcggtgat tctggcgacg accgaagata
    22681 cctgggggca actctttcaa aaaatggggc gcggctatca gcagccaaaa ctggtgatgt
    22741 accgtggtat gacgcgtacc ggctgtggtg cgggtcagtc cgtgatgggg ccgttttact
    22801 gcccggcgga cggcaccgtc tatatcgatc tctcatttta cgatgttatg aaaaataagc
    22861 tgggcgcgga cggtgatttt gcccagggtt atgttatcgc ccacgaagtc ggccaccacg
    22921 tacaaaaact gttaggcatt gagccgaaag tacgccagtt acaacaaaac gcgtcgcaaa
    22981 cggaggtgaa tcgcctttcg gtgcgcatgg agctacaggc ggattgcttt gccggcgtgt
    23041 ggggacacag tatgcagcag caaggcgtac tggaggcggg cgatctggaa gaggcgctca
    23101 atgccgcaca ggctatcggc gacgatcgct tacagcaaca ggggcagggg cgcgtggtgc
    23161 cggatagttt tacccacggc acctcagaac agcgctacag ctggtttaag cgtggatttg
    23221 acagcggtga cccggcgcaa tgtaatacgt ttggtaaaaa cttttgataa actggggcag
    23281 ggatgtctga tatcgatgcg ctacgggcgt taacgtcgca aatgacacag gaaggcattc
    23341 gccgtttact ggtcatcagc ggcgatgcgg cgtggtgccg ggaacgggcc gaggcgatac
    23401 gcgctgtatt gcccggtgac tggtgggtcg cgcctgacgc gcccgcccag ccgcgctgta
    23461 cgccacaggc gttacaaacg ctgctgggcc gtgaatttcg tcatgcgata tttgatgcct
    23521 ggcagggctt tgacgccgca gcgtttgccg ccctgagcgg gaccttgcag gccggaagtt
    23581 ggctgcttct gctgatgccg ccgtatgaga cgtgggaaag ccggcctgat accgattcac
    23641 tgcgctggag cgactgcgcg cagcctatcc ccacaccgca gtttgcacag catcttaaac
    23701 ggactctttc ccgcgatccg caaacgctgc tttggcgaca gcgccagccg ttttgctggc
    23761 catcttatcc ttcccgcgaa cgctggcgac ccgccaccgg cgagccgcag ccggagcagg
    23821 cggctatctt atcgcgttta cgtgaaatgc cgcccggcgt ggcgacggtg attgcccccc
    23881 gtgggcgcgg caaatcggcg ctggccgggc aattcatctc acagatggcg ggcacggcta
    23941 tcgtgaccgc accggcgaaa acggcaacgg atatcctggc agcgtttgcc ggtgagcggt
    24001 tctgctttat ggcgccggat gcgctgctgg cgagcggggc aagagccgac tggctggtgg
    24061 ttgacgaggc ggcggcaatc cccgcgccgc tgctgctgca actggtttcg cgctttcccc
    24121 gcatactact caccaccacc gttcagggct acgaaggcac cggacgcggt tttttactta
    24181 agttttgcgc ccgttttccg cagcttcacc gctttacgct tcgtcagcct gtccgctggg
    24241 cgccagaatg cccgctggaa aatatcgtca gcgaggcgct gatattcgac gatgaagcgt
    24301 ttgcgcaggc gccgcatggc gggatagcaa tctcggcatt ttaccagcag gcctggggga
    24361 agacgcccgc gttgccgagg gctgtgtatc agttactgtc gggggcgcac tatcgtactt
    24421 cgccgttgga tctgcgccga atgatggatg cgccaggaca gcatttcttg caggctacgg
    24481 cgaataaccg tgtggcgggc gccctctggc tggtcgaaga gggcgggtta tccgcagagc
    24541 tcagtcaggc tgtatggtgc ggtttccggc gtccgcgtgg aaatctggtg gcgcagtcgc
    24601 tggcggcgca cggtagcgac cctttagccg cgacgctggt cgggcgtcgc gtaagccgta
    24661 tcgcggtgca ccccgcccgt cagcgcgaag gcatcggtca gcagttgatt gcctgcgcgt
    24721 gcgagcaggc ggcgcagtgt gattatcttt ccgtcagctt cggctatacg ccggagctgt
    24781 ggcgcttctg gcaacgctgc ggctttgtgc tggtacggat gggcagccat cgggaggcga
    24841 gcagcggttg ctatacggcg atggcgttat tgccgctgag cgacgcggga caacggctgg
    24901 cgcaacagga acaccgacgt ttgcgccgcg atgcggatat cctgacgcag tggaacggcg
    24961 aggcgatacc gctggcggcg ttgcgcgaac aggcgcttaa tgatgaagac tggcgtgagc
    25021 tggtcggttt tgcgttcgcg caccgcccgc tactgacatc gttaggttgc ctgcatcgtt
    25081 tactgcaata cagcgcattg ccattgccgg cgctgagagg gcggctggag gaaaaagcca
    25141 gcgatgccga actgtgcgcc cggctacgca tttcaggccg taaagctctg ctggcgttgc
    25201 agcgtgcgca ggcggcgcag gcgctaattg cgttggatgc cggacgaacg cagcgtttgc
    25261 gcgacgtaat gccaggcggt ggggaccatg ccggatagcg atacctgtcc ggcatgttat
    25321 ccggttactt tttcggctga tctttcttcg gccagtcgtc ttcatcgtcc cacttatcgt
    25381 taaaatcgcg atgcgggggc agctcaggtt tgttggcaag gaatttctta tggtcgatgc
    25441 gtttgagatc tttgatcaca ttcagcagta cgcctaccag aaacaccaat accagaatcc
    25501 accaatattt tgccagccag tccatgctta tttcctctta ccggaacgct catcaggcga
    25561 cgagctgttc cataatacgt tgatacatac gggccagtag ctggagatcg gcggcattca
    25621 cacattcgtt aattttatga atggtggcgt tcaccggccc cagttctacc acctgcgctc
    25681 ccatacgggc gataaaacgt ccgtcggacg taccgcccgt cgtcagtaat tgcggtttaa
    25741 tttcattata gtgctcaatg gcgtttacca ccgcgtccac cagctttccg cgtgcggtca
    25801 ggaacggctg accggaaagc caccagtcta cggtatagcg tagctgatgc ttctcaagca
    25861 gcgcatgtac ccgttctttg atcatctcat cggtcagctc cgtgctaaaa cggaagttaa
    25921 actgcacgaa cagttcgccg ggaatgacat tattgctgcc ggtgcctgcc tggatattgg
    25981 ctatctgcat actggtggcc gggaaaaagt cattgccccg atcccactcg atagcgacca
    26041 gttcattgag aaaaggcgcg gcgcgatgaa cagggttatc cgccagatgc ggataggcaa
    26101 cgtgcccctg aacgccatga atagtgaggt tacaggtgag ggaaccgcga cgcccgtttt
    26161 tgacgacatc gcccacaatt tcagtactgg aaggttcgcc gaccagacag taatccagcc
    26221 gctcgttacg ggccatcagc gcttcaacca cctttacggt gccatttttt gcgctggctt
    26281 cttcatcaga ggtaatcaaa aatgcgaggc ggccccggtg atgaggatgc tgtgcaacaa
    26341 aacgttcagc agccaccacc atggccgcca gtgaaccttt catatccgcc gcgccgcgac
    26401 cgaacaacat tccgtcgcga atcgtaggtt caaacggcgg attgatccag cgatcgacat
    26461 cgccagccgg tacgacgtca gtatgcccgg cgaacgccag cgtttcgcca cgcccacgcc
    26521 atgcccaaaa attttgcgtg tcgccaaaat ccatatgctc aatggtaaaa ccgattttac
    26581 gcaggcgttc aatcattaat gcctgacagc ctacgtcatc cggactcagg gaggggcgac
    26641 gaataagttg ctgtgtcagc tcaataaccg ggcacgacat agactacacc tcatcaaaaa
    26701 actgctgata acgggattca ctgaaaccaa gcagcatagg cttcccgggc gcgcagagca
    26761 atgggcgttt gatgattgcc ggctgttcaa ccatgagagc agcggcggag tcggcatcgg
    26821 taatcccgct gcggtggcct tcatccagtt tgcgccatgt tgtgccgcgc gtattcagta
    26881 aaggctgcca gccgagttcg gcaataaagg tattaagaag agggaggtct atgccatcca
    26941 cacggtaatc gtgaaaacga taatcaatgc catgctcctc cagccaacgg cgcgcttttt
    27001 tgatcgtgtc gcaattctta atgccataga gggtaatcat attgaatcct ttaacgcgaa
    27061 attcgaataa ataatcaata gtatcgtctg cgggataata agtgtggctg ttaatggtta
    27121 tttatccagc gctgatcggc aatcaatata acattgttga gtgaatgtga ataatgattc
    27181 caaaacgttc cagatgtggc ttgtttataa ttcgtgagga aaatcctatt ttgcgcacat
    27241 gcaattgatt gttttttaac ccgatttgat aaagtagtag aaaaggtatt aatgttgcta
    27301 aatattgcag taagtcacat aaaat
//
LOCUS       DAJVBX010000034        26859 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.034, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000034 DAJVBX010000000
VERSION     DAJVBX010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 26859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26859
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.034"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..485)
                     /locus_tag="OPV72_001294"
     CDS             complement(<1..485)
                     /locus_tag="OPV72_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCR9913648.1"
                     /translation="MANLPETPQWESGIYQIEVSDPVLGGPDGISNRQAKQLASRTSY
                     LKQKVEKSGTDLAAHIAAVDPHTQYATKASPTFTGTPTAPTPANGDNSKKLATTEFVA
                     KALAALAGSAPETLDTLKELADALGNDPNFATTVLNKLAEKLAKDQNGADIPEPALFV
                     K"
     gene            complement(488..1066)
                     /locus_tag="OPV72_001295"
     CDS             complement(488..1066)
                     /locus_tag="OPV72_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein I"
                     /protein_id="HCR9913649.1"
                     /translation="MAEVLQLPPPLEGDISLRTLGRLAGRLDNIDLSVLMVGLVDIVD
                     SSALPWLGEQFSLFGDGWELAESDDVRRMLIKSAIELHRYKGTPWSIREIIRRFGFGE
                     VDLIEGTGQIGYDGRHTYNGLFVHGDAQAWAVYRVILQQPITNDQAALLRQTLAAFAP
                     ARCHLASLEYQSVAIRYNSTTRYDGSYNHGSS"
     gene            complement(1059..2162)
                     /locus_tag="OPV72_001296"
     CDS             complement(1059..2162)
                     /locus_tag="OPV72_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016191672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HCR9913650.1"
                     /translation="MALTEPDFIERDADKITAEMIAKYEADTGKTLYPAQAERLLIDL
                     WAYREMLVRVAVQEAAKQNLVAFSREPMIDYLGELVDVYRLAAQPATTTLQFSVDEAL
                     AIDVLIPAGTRVSASDSIIFATDTDVVLKAGLLLVNVTATCTEPGTAGNGWQPAQVSQ
                     LLDEIDNIDLLVTNLTASSGGSEQEDDDRLRERIRLAPESFTNAGSRGAYRFHAMGAH
                     PGIVDVAVLSPAPGTVELYPLLSTGLPDSSILTLVESFCSDEKVRPLTDTVRAKTPVQ
                     VDYTIEARITIYRDQDARLVKDNANSAIQNWVASRTATLGRDIVPSQIISVLSVSGVY
                     QVELVTPALRVVAENEWANCTAITLNMTGVSDG"
     gene            complement(2153..2500)
                     /locus_tag="OPV72_001297"
     CDS             complement(2153..2500)
                     /locus_tag="OPV72_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPW/gp25 family protein"
                     /protein_id="HCR9913651.1"
                     /translation="MKTTSVFWQPALQAPGEIVRGLDDIRQSIQIILRTPRGSDPHRP
                     EFGSNLHLYIDWPVGRAIPHVVRESVDAIRRWEPRCQLMSVKPAVDGEHLTLRVSWKG
                     SDGQPRTQELLWR"
     gene            complement(2557..3084)
                     /locus_tag="OPV72_001298"
     CDS             complement(2557..3084)
                     /locus_tag="OPV72_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006122455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate assembly protein V"
                     /protein_id="HCR9913652.1"
                     /translation="MTGVTRQIGTVSAVDADRVQARVRLPECDNLRTNWLNVLQRNTQ
                     DNKDYWLPDVGEQVEVLLDANGEDGVILGAVYSDVDKPPFSDKNVRGTKYADGAEFSY
                     NRATHTLTVRGGIERIVVEVAADISLKGKNLDLTGVTTINGPATLNGDLEINGSAHAT
                     GNIFADGQNSNHHSH"
     gene            complement(3081..4235)
                     /locus_tag="OPV72_001299"
     CDS             complement(3081..4235)
                     /locus_tag="OPV72_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001545521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage late control D family protein"
                     /protein_id="HCR9913653.1"
                     /translation="MAEINSTAQATSALTSVSDVLTPVFTLWYLQKNITSDIAPYVTR
                     VVWSDNIKNESDTIEVELDDTDGRWLDKWYPGKGDTLTLKMGYQGEKLLSCGTFSIDE
                     IEVSSPASVVAIRGVATSVNSALRTKSSRGFENTTLAAVAGRIARKHRLKLVGSIESI
                     KIDRVTQYAETDVGFLRRLASEYGYAVKVVSDQLIFSHLATLRSQEPVRQLKPQGVAR
                     FSLRDTINRVYKSAKVKHQKSSSKKLIVYEADGGTRESDKKLKGGKVTSADSLKVNSR
                     VSDPDSARIKADSALARHNEYQQNGSLTLTGTPQLTAGNKIELVGFGQLSGPWLIITA
                     RHAFERNSGYTTELEVARGPVTRGKKQKTQKLTVYHPDGSTSTVIKEKKK"
     gene            complement(4223..4435)
                     /locus_tag="OPV72_001300"
     CDS             complement(4223..4435)
                     /locus_tag="OPV72_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail protein X"
                     /protein_id="HCR9913654.1"
                     /translation="MFLEHITRDGERWDSLAWQYYGDPLGYPRIIAANPHVAITPVLP
                     SGLLLLIPVIEAEDARTEEDIAPWLR"
     gene            complement(4435..5319)
                     /locus_tag="OPV72_001301"
     CDS             complement(4435..5319)
                     /locus_tag="OPV72_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001423226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCR9913655.1"
                     /translation="MFAVLGDIEFELITYWDGFEATFGVDYAEHARIEGKPGLQFVGD
                     RLDEIQISLVFHQHYCVPDVELARVRTAMKAHQALALVFGNGDYRGWFVITDVTATSE
                     QTDSTGNVLAVSATVSLREYTGDPKNPLQPPAIRRQVPGAGAVSGAVPSPSGVAQFVR
                     NGVNYAKQAQSVLQTTISAVRVAQKMKGNPVVALTRVPGLMSGLGNISGALGKSVPAF
                     NALSESMPDAISLARTASEAATYVQQAQSALSGVDKRNIAGALDTVSGQLNAAGTAFN
                     RMSPGLSAMAARILTRSV"
     gene            complement(5319..7784)
                     /locus_tag="OPV72_001302"
     CDS             complement(5319..7784)
                     /locus_tag="OPV72_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001716231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HCR9913656.1"
                     /translation="MASEFSVGVIIGGIVGSSFRSAVSGTRRALDSLGDTSRRLQERQ
                     NALTRATERYGQLGSSRMQHLNSELLRVSRTMEQIERQQRRLSAVSATGDALKANRLA
                     LYGQGAETYAIGRTLGAPVMASVKQYASFESQLRDISVTGDLDAKQERAIGQAIRQAS
                     LKVNQLQESLLGGVGQLVADGMAPERAATFAEMLGKTATATKADMTDLAKMTYAFSDA
                     LRITDAKELEQAFGIAATGAKLGSFELKDMAKALPGMAKAFAARGIYGKDAITQIVAS
                     LEVGKGSGSAEEAVTNMSNWLAAMGRGDTIQKYAKAGVDYQGSMQNYVAQGFSQYEAS
                     LMIANRFIDSKGKAFLQQWKAAGARGDQEGQQKLMESFGLAEVFTDIQTVNHLLSMRQ
                     GWDKYLSSKQEMNAPAAISTLDKDAAKQNDTLEGRWRRMQIGFNDSAISIGQSLRPAL
                     LQLGETFIPLMDSVGKWIAANPQLVSSTIKVVGALLAFRMATIGLKLGLNLLLSPFVS
                     VWKNAVLLRANWLRLTLALGEGGKLRWLVTGFGAVARGARTLGGVLSGGLVRGIMSAG
                     RAVLWIGRALLMNPIGLVITAVAAAAYLIYRNWGAVSSWFKQRWADIQEAFNGGIVGI
                     GKLLVNWSPAGLLYKAFAAALKYLGVDLPAKFTDFGGHLIDGLINGIRNKWASLKTSV
                     TGMGDSISDWFSEKLGIHSPSRVFMGFGDNIAQGAAIGLQRTTPLAALAGQRLAAEMT
                     PDVPRIPSPEIMAAGYSGRGATATGGGASGGIKVSFNPQFFLNGKETAAPAGLTGALN
                     MSLHELEKMLERLLAQKQRKEYS"
     gene            complement(7878..8015)
                     /locus_tag="OPV72_001303"
     CDS             complement(7878..8015)
                     /locus_tag="OPV72_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006122450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GpE family phage tail protein"
                     /protein_id="HCR9913657.1"
                     /translation="MQAQGLLARWFRFQPGEIDALDTDDLEMWLEQAEEQIKSEFGDN
                     Q"
     gene            complement(7960..8295)
                     /locus_tag="OPV72_001304"
     CDS             complement(7960..8295)
                     /locus_tag="OPV72_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly protein"
                     /protein_id="HCR9913658.1"
                     /translation="MSQTQSDTFTLSYPFTTAAGTRIEQIELKRLTVKDLKQVRKINK
                     DPADWDEPLIARSTGILPEDLDNMDLADYMELQKRFQKITGLGKSDKNTDAGAGPAGE
                     MVQVSTGGD"
     gene            complement(8393..8674)
                     /locus_tag="OPV72_001305"
     CDS             complement(8393..8674)
                     /locus_tag="OPV72_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000110114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913659.1"
                     /translation="MSVELTDKGGRCASLGMSNGTWFTLLDIPGVETLFNTRKTNDPI
                     DCTRSKARKLADLIEAWKPPDQWFSGTGKSEGKALLIAFLRNCKGFRTC"
     gene            complement(8677..9201)
                     /locus_tag="OPV72_001306"
     CDS             complement(8677..9201)
                     /locus_tag="OPV72_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail tube protein"
                     /protein_id="HCR9913660.1"
                     /translation="MMSKIEINRITNANIYLDGTNLLGRAEEVKLPDVSMIMQEHKAL
                     GMVGKVELPAGFDKLEGEIKWNSFYRDAMLSAANPYKSLALQCRSSVQRYSSQGLIDE
                     IPLVTFLTIMFKKNPLGTFKQHENAEFSSSFTCTYIRQVLDGEELLQLDYLANIFRVG
                     GVDQLTDYRINIGG"
     gene            complement(9198..10625)
                     /locus_tag="OPV72_001307"
     CDS             complement(9198..10625)
                     /locus_tag="OPV72_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001610519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HCR9913661.1"
                     /translation="MAANYLHGVETIEVENGARPVKTVKSAVIGLIGTAPMGDVNTLV
                     QCLSEKDAAAFGSQFTGFTIPQALDAIYDHGAGTVLVINVLDPSVHKIAVVSENVSFD
                     KATGRARLANPVVAQLVLKPDSNGQPYVEGQDYSLDAQTGVITNLGKSIAADATVKAS
                     YNYADPTKVTPADIIGTVNAAGNRTGMKLLNDSFNLFGYFAKILIAPVFCTQNSVSVE
                     LIAMAEKLGAVTYIDAPVGTTFAQALAGRGPEGTINFNTSSDRVRLCYPHVKVYDPVT
                     NTERLEPLSQRAAGLRAKVDLDKGYWWSSSNQEILGITGVERQLSAMIDDPQSEVNLL
                     NEQGITTVFSSYGSGLHLWGNRTAAWPTVTHMRNFENVRRTGDVINESIRYFSQQYID
                     MPITQALIDALTESVNAYGRKMTGDGAVLGFRCWFDPARNPETELAAGHLLLSYKYTP
                     PPPLERLTFETEITSEYLLTLKGGN"
     gene            complement(10615..10866)
                     /locus_tag="OPV72_001308"
     CDS             complement(10615..10866)
                     /locus_tag="OPV72_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001513985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913662.1"
                     /translation="MKEYRYSGPASGVTLSDGTEILLWPGKTVSLPEEHDYVKVLVAL
                     KHLTPVPEDTKPAVTPAVQSPKRRSSSDSEVKTEDSHGS"
     gene            complement(10866..11330)
                     /locus_tag="OPV72_001309"
     CDS             complement(10866..11330)
                     /locus_tag="OPV72_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016191683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gp37 family protein"
                     /protein_id="HCR9913663.1"
                     /translation="MNVLPVLDAVLARLREKLPQLQVEYFPEKPAEYRLNHPVGALLL
                     SYAGSRFDRPDDTGAVIQSQTIQLCVTVVFRQLNGKKGAINVLDAVRRILGGHTPPGC
                     RRRIWLTREVFIGEVRGLWQYALDFATESVFIEDSDLPSGPLLTEVNYEESE"
     gene            complement(11330..11776)
                     /locus_tag="OPV72_001310"
     CDS             complement(11330..11776)
                     /locus_tag="OPV72_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1320 domain-containing protein"
                     /protein_id="HCR9913664.1"
                     /translation="MYCTLEDLLAQVPERTLIELTSEEMDFDSPATVNTRVVDSCIRY
                     ADELIDAHLRGRYILPLAEIPTVLRDIAITLVRYRLYARRPEGDLPDTVKDDHKEALR
                     QLRELRDNRLTLGLPSTQKDVPEPGEFRVRSRPATFGGRDGLLEKY"
     gene            complement(11778..12116)
                     /locus_tag="OPV72_001311"
     CDS             complement(11778..12116)
                     /locus_tag="OPV72_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016191685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2190 family protein"
                     /protein_id="HCR9913665.1"
                     /translation="MGTTQQVILITTVTAGAALAQQRFVGADNTPCKAGAAALGVAEV
                     DAVTGDSTPVSVLGIIAVEAGAAVSRGVAVQSDAQARAVPQSGDGKSCGIALDEAGGE
                     GDVIRILRGV"
     gene            complement(12126..13079)
                     /locus_tag="OPV72_001312"
     CDS             complement(12126..13079)
                     /locus_tag="OPV72_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015365646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913666.1"
                     /translation="MSDYLKGKRVVDPVLTSIARGYKNAAFIGERIFPVVLTDKEGVR
                     VPTFGKTAFVEYDTERAVGADSNVLVREKTGTLDLVLGEHDLAAPVDYREQAESMFNE
                     ESKAIRRATNGVNLRRELIAARLAQDEKVYRTGHVKKLTAGDRWAGGKGDPIGVIEAG
                     MEAVRTATGLRPNLMTMGAGVMALLKFHPAIQAAIGANERKRITTEILQDLFQIEEIV
                     IGAPVSLPSMKAAMDKDSVPTDIWGDNLMLHYVGKPQPGADSADENEPSFGYTLRRKG
                     MPVADKYDGAGGKVKYCRYTDIYKVAVVGGDAGYLITGISK"
     gene            complement(13094..14209)
                     /locus_tag="OPV72_001313"
     CDS             complement(13094..14209)
                     /locus_tag="OPV72_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HCR9913667.1"
                     /translation="MSAIHIFKAGTHTDMHGKKLPFTPDDLAACVKAYDPSVHEAPLV
                     IGHPRTEDPAWGWVKALSLSGVDLMAEPAQLDPQFAEMVTDGRFKKVSASFYLPDSPS
                     NPKPGVLYLRHVGFLGAQPPSVKGLKQVSFSEQEEGVVEFADWQAITNASLWGKLRDF
                     LIARFSLDEAEKVLPEWQLNSLREEAYRDTLSQDAAGAQFSETGPGPSSASNEESSMT
                     KEEIEALQEENRRLKQQAADRDARDAQVRQEQLHKDNVAFAEKLVAEGRLAPRASSVV
                     VALLDAVAGGDKPVEFAEGESRTPLATAFRSLLSDGEPVMNFAEQATKDRVGDAVKVD
                     VAEFAEADPERLALHQKAVALSKKEGISYEAAVARCL"
     gene            complement(14424..14882)
                     /locus_tag="OPV72_001314"
     CDS             complement(14424..14882)
                     /locus_tag="OPV72_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000135514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage virion morphogenesis protein"
                     /protein_id="HCR9913668.1"
                     /translation="MASDNLVSITINDKSLRRSLRALDLAATDMEPAMRKIAGTLLAE
                     TQFNFLDEGRPGWMPSLAAEERDGQTLQDTGRLMGSVSTDHDDRQAVVGTNVVYGAIH
                     QFGGKTGRNESVELPARPFLPVTGDGELQPEVVIPILDTIVRHLESAARR"
     gene            complement(14885..15706)
                     /locus_tag="OPV72_001315"
     CDS             complement(14885..15706)
                     /locus_tag="OPV72_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016191689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HCR9913669.1"
                     /translation="MSVTTAELAYCMTLPPKRAVSYLKSKGYQITWDWEEMWQEAHAR
                     AFTVAKVTRLDILEDIRGALQQAVDEGKTDRWFRQELEPVLKRKGWWGPRDTTDPVTG
                     KPVTIQQGSPWRLDTIFRTNMSVLYSAGRWAEQMENVDDRPYWMYTGINDSHTRRSHL
                     ALHGLVLRWDDPFWQAFYPPNGWRCRCSVIALSATDVRARGLKVISSGSAMGQELKLV
                     SEKTGEMRNVATFNTGTTKVTTDVGWSYAPGAAYRPDLARYQGTLQPLAQQELRG"
     gene            complement(15687..17183)
                     /locus_tag="OPV72_001316"
     CDS             complement(15687..17183)
                     /locus_tag="OPV72_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016240624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF935 domain-containing protein"
                     /protein_id="HCR9913670.1"
                     /translation="MARGIWVSPDEFVAFSEPQKSLTAQIASRSRAIDFYGLGMYLPN
                     PDPILKAQGRDIRIYRELRTDPLVGGCIRRRKAALKSLERGLERGHASARVFRFIRDM
                     LDDLDLSRIIGEMSDAVLYGYQPCEIMWGRSVRAWAVTDIVGKPPEWFQFDTDNCLRF
                     RARDAGVEGELLSPSKFVVPAQDASYDNPYGFPDLSMCFWPVAFKKGGMKFWLRFAEK
                     FGSPWVIGKHPRGANDAEIEKLLDSMEQMVEDAVAAIPDDSSIELKAADGKADSSEVF
                     RELITLSRSEISIALLGQNQTTEANSNKASAQAGLEVTADIRDADADIIQAAVNQVIR
                     TVVTLNFGDVPCPVWAMWEQETIDDTRATRDEKLTRAGLRLTPQYFKREYQLQDGDID
                     ETPPSERQNNMLPLSFAEAIDADIQAQQQLDDALDILMNGGVLNGTLEPVLAPLFKRV
                     ENGVNPTELLGELAELYPQMNTDDLQERLARILFVANIWGRLHERDNG"
     gene            complement(17183..18724)
                     /locus_tag="OPV72_001317"
     CDS             complement(17183..18724)
                     /locus_tag="OPV72_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000080258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913671.1"
                     /translation="MSPMDGRNNLAPVLPDTSALDAPPVLLPYQQRWVADTSPLKVIE
                     KSRRTGITWAEASDNVLTAASSAPAGGMNVYYIAYNQDMTVEYIQACAMWARAFNYAA
                     SEIEEGFWEEDDDDKHIKTYTIKFPDSGFRIVALSSRPSNLRGRQGIIVIDEAAFHEQ
                     LDELLKAALAMLIWGGKVRVISTHDGDDNPFNTLIGDIRAGRQGGSVHRITFREAVSE
                     GLFRRVCLRTGKEWSEASEQAWMASVYKFYAAGASEELDCIPANGGGAWLSRALIESR
                     MSADTPVLRLTCQEGYELLSDEVRFHETQDWLDEHLKPLLEALPADARSFLGRDFGRS
                     GDLSVDYPLLQEKNLVRRVPFVLELRNVPFRQQEQITWYLMDGLPGLLGAAFDARGNG
                     AYLAEYAMQRYGSSRVQQVMPTEGWYREHMPPVKAALEDGNLVDLPKDEDTLDDLRAV
                     QVVNGVPRVPEQRSKAKADGGKRHGDSAIALALAYFASREINKGPVKASSRCRRQAAR
                     MLEGF"
     gene            complement(18775..19320)
                     /locus_tag="OPV72_001318"
     CDS             complement(18775..19320)
                     /locus_tag="OPV72_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001696566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3486 family protein"
                     /protein_id="HCR9913672.1"
                     /translation="MARRSTIEKLPEDVRRWLERALTESGFSGYNELESLLRERGYVI
                     SKSAIHRYGQKIERRYGAIRAATEAARMLTEGAADDQDARSEAVIALIQTELFESIVQ
                     LQEAEEGEVDPKERVALLSKVAKNVATLSRASVNLKKFQSEVRARAQQAASNAEKIAR
                     KGGLSSDAVQALRREILGIAT"
     gene            complement(19320..19631)
                     /locus_tag="OPV72_001319"
     CDS             complement(19320..19631)
                     /locus_tag="OPV72_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913673.1"
                     /translation="MVDITRVRRESLRWSLLVALNKTRPYTASETLLLDVSRAIYPDT
                     TPLELRRELDYLADRKMVDLEKKPSGDWFADLTRLGVDLVEYTVECGPGIARPEKYWS
                     E"
     gene            complement(19631..19957)
                     /locus_tag="OPV72_001320"
     CDS             complement(19631..19957)
                     /locus_tag="OPV72_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913674.1"
                     /translation="MTLQVEFWTVVSFLLTFMGFVGGLAKWLFSKTEERQAARFASLE
                     QALQQSASNWGELEKEFMRFKADLPLNYVRREDYIRGQTVIEAKLDALYNKLEVVQQY
                     RNTGGQ"
     gene            complement(19954..20604)
                     /locus_tag="OPV72_001321"
     CDS             complement(19954..20604)
                     /locus_tag="OPV72_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000264665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCR9913675.1"
                     /translation="MWHLVKKLPWRGILLAILINAFLVGLYAMGYRSGHDSAKRDGDT
                     ALSQLQSAFDAYKTEQATLENAALRAWARRYQEQVAAGQRAEAGYLEQIAQLESRNKQ
                     LQGQINDVTQRWIDEKGKSHPIECVFTRGFVRQYNAALGYDNASVDTGHSDSVAAAGT
                     RSGTATGQPETTDTRLRDSGVSQRDVLANIIDNAGQCRRWRNQINALLDEREGLQK"
     gene            complement(20588..21316)
                     /locus_tag="OPV72_001322"
     CDS             complement(20588..21316)
                     /locus_tag="OPV72_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HCR9913676.1"
                     /translation="MNWPQITLIILFAFGLGVTAIRHGEPRNDKYSFWWQLAGNLVIV
                     WLLWCGGFFSQARAAQPPQAALQYRDDVIRNARLEWGLSAPVADFAAQLHQESGWRPD
                     VVSPAGAQGLAQFMPATADWISQLIPMLSNREPFNPAWAIRALVSYDRWLWQRVSAAN
                     DCERMAMTLSGYNGGLGWVQRDRRLASQKGLDSTRWFGHVATVNAGRNAASWRENRHY
                     PQRILRELAPRYLTWGGCSCVASG"
     gene            complement(21319..21669)
                     /locus_tag="OPV72_001323"
     CDS             complement(21319..21669)
                     /locus_tag="OPV72_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015365653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin"
                     /protein_id="HCR9913677.1"
                     /translation="MKNLKKFIPPVKKPRLSGWLLTSVLLLGIIALVSPQQLPVVIYK
                     LALITLAAVLGYWLDRSLFPKARPGQYLKHDDRLMAEGRFPVQTGLHLVFSAALIRRA
                     LIVAAVCLAVATGL"
     gene            complement(21913..22509)
                     /locus_tag="OPV72_001324"
     CDS             complement(21913..22509)
                     /locus_tag="OPV72_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HCR9913678.1"
                     /translation="MILTDVRYASPNSLSNGDASERLSPEEGLVTEASQRLINDICAK
                     YAGRTQFLGCNDVLIAKRESEKLRDVLKAFAAEKELDGAEKDAFLKSAFEHLHALSKA
                     GEPLSLETLVNAIWPQAPEELSGKLAAEELELSDGFVPDGRVIRALVSFKGKSKYWEL
                     KFDREGKTEGYIDYDPETNIITLRNVPEEFREMWMTEV"
     gene            22553..22936
                     /locus_tag="OPV72_001325"
     CDS             22553..22936
                     /locus_tag="OPV72_001325"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913679.1"
                     /translation="MPTLAHLGKAKLFELMTEDDEELAELADGGTVAGLTLDDVDRMS
                     VRELRQALREARETNAAQQRVLADKNEKIDSLSTRLEKKSRIQPPEPDEEVKKLRAEV
                     TALAVEAESAIAVRLSSAFETLCAY"
     gene            22946..23110
                     /locus_tag="OPV72_001326"
     CDS             22946..23110
                     /locus_tag="OPV72_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001330525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913680.1"
                     /translation="MIDTPRDFMAGLVCQLESTARSLRSTFDLPDEPTGNAAPSWLTE
                     PTPQINGLEA"
     gene            23114..24883
                     /locus_tag="OPV72_001327"
     CDS             23114..24883
                     /locus_tag="OPV72_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001756569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HCR9913681.1"
                     /translation="MNAALTERLVYVARAARDAGHGKRGAIYDAACAELGMSRATLLR
                     RLKEVSVTDKRKKRADAGRSALTRDEAALISATLREATRKNGKRLYSIADAVETLRAN
                     GFISAGRTDETTGEFFPLSEDAISRALRNYGLHPEQLDAPAPYTEVASLHPNHVWQID
                     ASLCTLYYLSNGHKGLQVMDSAKFYKNKPANLARIASDRVWSYEITDHASGWIYVEYV
                     TGAESGENLCSVLINAMQERGGADVLHGVPKILYLDPGSANTAGMTKNMCRSLGIDLI
                     AHKPHNARATGQVEKARDIIERKLEPGLKFRPVHSLEELNALAAKWRSHFNATAVHSR
                     HGKTRTDIWLKITAEQLKKAPSVEVCRELAVAAPELRKVTPKLRVSFRGTEFDVSTVP
                     GVLVGEKLMITRNPWRSDVAQVVLTGEDGHETFFLVEEVRKNEFGFAEGAAVFGESYK
                     ALPETPAQMAAKETEALVTGTDNAADAAAARKAKALPFGGRLDPYKHIDDATLPACIP
                     KRGQASDVRGPRTEQRPMTHVEAAKALRGKFSANGLTWTPEHYRQLTAQYPDGVPEAA
                     LDEVMATLTTPARSSVISIVNGN"
     gene            24894..26060
                     /locus_tag="OPV72_001328"
     CDS             24894..26060
                     /locus_tag="OPV72_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020803496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCR9913682.1"
                     /translation="MLVLKQQLKEARIPQAVVARAVDVSEATLAQIVNHNAWPRTSPG
                     EVRRRLASWLESQGIDTAKSFDAVQGAATPRTAGTTDKTSLSEEENMLLKKQVLFPAT
                     KKAFGLFRDPFADEAMQGSDDVFTTPDIRYVREALYQTARHGGFMAVIGESGAGKSTL
                     RRDLTERINRENAPVIVIEPYIIAMEDNDVKGKTLKAAAIAEAIISTIAPLESIRRSQ
                     DARFRQLHRVLKDSNQAGFSHVLVIEEAHSLPIPTLKHLKRFFELESGFKKLLSIVLI
                     GQPELATKLSERNMEVREVVQRCEVVELLPLDNHLEEFLTFKLQRAGKQLTDIMDASA
                     VDAIRTRLSNPGSHRKNMVSLLYPLAVSNLVIAAMNLAAEIGVPQVNADVVKGV"
     gene            26063..26332
                     /locus_tag="OPV72_001329"
     CDS             26063..26332
                     /locus_tag="OPV72_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913683.1"
                     /translation="MKSTTGINQQISKVQSAIMALKATNTDVQSITIRGNKPVIRVSR
                     SAHCMRMLEQGKACYLYTGHDHRGYFRQGVFELHGCRVVWPESLW"
     gene            26360..>26859
                     /locus_tag="OPV72_001330"
     CDS             26360..>26859
                     /locus_tag="OPV72_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001576700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host-nuclease inhibitor Gam family protein"
                     /protein_id="HCR9913684.1"
                     /translation="MAKSTKGAKRIKAAAALWVPGTREEVIEGIRLLGDAHRELVRAE
                     TEMNDAIGDITARYAPLTESLKKRMAELQSGIQTWCEAHRDELTGNGKVKFANLTTGE
                     VQWRNRPPSVSIRGADNVIELLRRLGLERFIRVKEEINKDAILNEKEAVKNIPGISIK
                     SDIEDFS"
BASE COUNT         5899 a         7768 c         7233 g         5959 t
ORIGIN      
        1 tttttgacaa acagcgcagg ctcaggaata tctgcgccgt tctggtcttt agccagcttt
       61 tccgccagct tgttcagtac cgtagtcgca aagtttggat cattaccgag agcgtcagcc
      121 agctctttaa gcgtatccag tgtctcaggg gcgctgcctg caagtgccgc aagtgctttg
      181 gccacaaact ccgtcgtcgc cagctttttg ctgttatcac catttgcagg tgtaggtgct
      241 gttggtgtgc cggtgaatgt cggactggct ttcgtcgcgt actgggtatg cgggtcaact
      301 gccgcgatat gtgcagccag gtctgttccg cttttttcga ccttctgttt gaggtatgac
      361 gttcggctgg ccagttgttt agcctggcgg ttagaaattc cgtcaggtcc gcccagaacg
      421 gggtcagaga cctcaatctg gtagatgccg ctttcccact gcggggtttc gggtagattt
      481 gccataatta actgctcccg tggttgtaac taccgtcata acgggtagta ctgttgtatc
      541 gaatggcgac agactgatat tccagacttg ccagatgaca gcgagccgga gcaaaggcag
      601 caagcgtctg acgtaacagc gccgcctgat cgttagtgat gggttgttga aggatgacgc
      661 gatagactgc ccaggcttgt gcatcaccat ggacgaaaag cccgttgtac gtgtgtctgc
      721 cgtcatagcc aatctgcccc gtaccttcaa tcagatccac ttcgccgaag ccaaaacggc
      781 ggataatttc ccggattgac cacggtgttc ctttatagcg gtgtagctcg atagcggatt
      841 tgataagcat gcggcgtaca tcgtccgatt ccgccagttc ccagccatcg ccgaacagcg
      901 agaactgctc gccaagccat ggcagcgcgg aactgtcgac aatatcgacg agaccgacca
      961 tcagtacgct caggtcgatg ttatccagcc gtccggccag tcttcccagc gttctgagac
     1021 tgatatcacc ctcaagcggt ggcgggagtt gtagcacctc agccatcgga caccccggtc
     1081 atgttaagag tgatcgctgt acagtttgcc cattcgtttt ctgccaccac cctcagtgcc
     1141 ggtgtcacca gttcgacctg gtacaccccg gaaacggaca acacgctgat aatctggctg
     1201 ggaacaatat cgcgccccag cgtggcggta cgggatgcca cccagttctg tatggcgctg
     1261 ttagcgttgt cctttaccaa ccttgcatcc tgatcacgat agatcgtaat cctggcttca
     1321 atggtgtaat ccacctgaac aggtgtttta gcccgcacgg tatcagtgag tggtctgact
     1381 ttttcgtcag aacagaaact ctctaccaga gtgaggatac tgctgtccgg cagaccagtg
     1441 ctgagcagcg gatacagctc gacagtgccg ggagcgggag aaagaacagc aacgtcgaca
     1501 atgccgggat gcgcccccat agcatgaaaa cggtatgcac cacggcttcc ggcattggtg
     1561 aatgactccg gggccagcct gatacgctcc cggagccggt catcgtcttc ctgctctgaa
     1621 ccgccagagc tggccgtcag attggtcacc agcaggtcaa tgttatcaat ctcatcgagt
     1681 aactgactga cctgcgccgg ttgccagccg ttgccagcgg tacccggctc ggtacaggtg
     1741 gccgtgacat tgaccagcag caatccggcc ttcagcacca catctgtatc ggtggcaaaa
     1801 ataatactgt cggaagcgct gacgcgggtg cctgccggga tcagcacatc aatggccagt
     1861 gcctcatcca cagagaactg aagtgtggtg gtggcaggct gcgcagcaag gcggtatacg
     1921 tcgaccagtt caccgaggta atcaatcatc ggctcacggg aaaaagcgac cagattctgc
     1981 ttcgccgcct cctgtactgc caccctgacc agcatttcgc gataggccca caggtcaatc
     2041 agcagacgtt cagcctgtgc cgggtacagc gtttttccgg tatccgcttc atacttcgca
     2101 atcatttctg ccgtgatttt atcggcatcg cgttcaataa aatcgggttc tgtcagcgcc
     2161 atagcagttc ctgagtacgg ggttgtccgt ctgagccttt ccagctcacc cggagcgtaa
     2221 gatgttcgcc gtcgacggcg ggtttaaccg acataagctg gcagcggggt tcccagcgcc
     2281 tgatggcatc gacggattcg cgaaccacat gcggaatggc ccggccgaca ggccagtcga
     2341 tataaaggtg cagattgctg ccgaactccg ggcgatgcgg gtcgctgccg cggggagtcc
     2401 gcaggatgat ctggatggac tgccggatat catccagccc ccggacgatt tcgccgggag
     2461 cctgcagagc tggttgccag aatactgagg tcgttttcat ggaggcagta ttgcccccgg
     2521 gaagtaagcg ccgatattaa aggcgtttaa gaaggttcaa tgggaatggt gattagagtt
     2581 ctgaccatca gcaaatatgt tacccgttgc atgggcgctt ccgttgattt ccagatcacc
     2641 attgagtgtc gcggggccgt tgatcgtggt aactcccgtg aggtcgaggt ttttcccttt
     2701 gagagagata tcagcggcaa cctccaccac gatacgctca atacctcctc tgaccgtcag
     2761 cgtatgggtc gcgcggttat aactgaactc cgcgccatca gcgtatttcg taccccggac
     2821 gtttttatca ctgaacggcg gtttatcgac gtctgagtac accgcgccca gaataacacc
     2881 atcctcgccg ttggcatcga gcagcacctc aacctgctcc cccacgtcag ggagccagta
     2941 atccttgtta tcctgggtat tgcgctgtag cacgttaagc cagtttgtgc gcagattatc
     3001 gcattcaggc agacgaacgc gggcctgaac cctgtcggca tcaacggcac tgaccgtacc
     3061 gatctgacgg gtgacaccag tcattttttc ttctccttaa tcaccgtcga tgtactgcca
     3121 tccgggtgat aaaccgtgag tttctgagtt ttttgttttt tccctcttgt gactggcccc
     3181 cgtgccactt ccagctctgt ggtgtagccg ctgttacgct caaacgcatg gcgggcagtg
     3241 attatcagcc atggaccgga taactgtcca aagcccacca gttcaatttt gttgcctgct
     3301 gtcagttgag gcgttcccgt cagcgtcagg gagccgttct gctggtattc gttatgtctg
     3361 gccagtgctg aatccgcttt aatccgggcg ctgtccgggt cgctgacgcg gctgttaact
     3421 ttaagtgagt cagcgctggt aaccttaccg cctttgagct ttttgtcgct ttcacgggta
     3481 ccaccatcag cttcgtagac gatcagtttt ttactgctgc ttttctggtg ttttaccttt
     3541 gcagatttat agacccggtt gatggtgtca cgcagggaaa agcgggccac accctgcggt
     3601 tttaactgcc tgaccggctc ctgactgcgc agtgtggcca gatgagaaaa aatcaactgg
     3661 tcactgacca ctttcactgc ataaccatac tcgctggcca gccggcgcag aaaacccacg
     3721 tcggtttcag catactgggt cacccggtcg attttgatgg actcaatgct gcccaccagt
     3781 ttcagtcggt gctttctggc aatccgcccc gcaacagctg ccagcgtggt gttctcaaaa
     3841 ccacggctgg atttagtccg cagagcactg ttaaccgagg tggccacccc acggatagcg
     3901 acaacggacg cgggcgaact cacttcgatc tcgtctattg agaatgtacc gcaggacagc
     3961 agtttctcgc cctgataacc cattttcagc gtcagcgtgt cacccttgcc cggataccac
     4021 ttatccagcc agcgaccatc ggtgtcatcc agctccacct caatggtatc ggactcattt
     4081 ttgatgttat cgctccagac cacacgggtg acataaggcg cgatatcaga ggtgatgttt
     4141 ttctgcagat accacagagt gaataccggc gtcagcacat cgctgacgct ggttaacgct
     4201 gatgtggctt gcgcagtact gtttatctca gccatggggc aatatcctct tctgtacggg
     4261 catcttcagc ctcaataacc gggatcagta acaacaaccc ggagggcagc accggcgtaa
     4321 tggccacgtg cggattggct gcaataatcc ggggatagcc cagcgggtca ccgtagtact
     4381 gccatgccag cgaatcccag cgctctccgt cacgggtaat atgttcaaga aacatcacac
     4441 actcctcgtc agtattctgg cggccattgc acttaatccc ggagacatgc ggttgaatgc
     4501 tgtgccggcg gcgttaagct gcccggaaac ggtatccaga gcacctgcaa tatttctttt
     4561 gtccacacca ctcagcgccg actgcgcctg ctgtacatac gtggctgcct cactggctgt
     4621 tctggccaga ctgatggcat cgggcatgga ttcagagagt gcattaaacg ccggaacact
     4681 tttccccaga gctccggata tattacccag tccgctcatc agtcccggca cacgggtcag
     4741 cgcgacaacg gggttaccct tcattttctg cgccacccga acggcactga tagtggtctg
     4801 gagtacagac tgcgcctgtt tcgcatagtt gacgccgtta cggacgaact gcgccacccc
     4861 ggaaggcgat ggaacagcac ccgatacagc tccggcaccg ggaacctgcc tgcgtattgc
     4921 cggcggttgc agaggatttt tcgggtcacc ggtgtattcc cggagagaca cggtggcact
     4981 gacagccagc acgttaccgg tgctgtctgt ctgctcgctg gttgcggtca catcggtaat
     5041 cacgaaccag ccgcgatagt caccgttgcc gaagaccagc gccagtgcct gatgggcctt
     5101 catggctgtt cgcactctcg ccagctccac gtcgggcaca caataatgct gatggaagac
     5161 taggcttatc tggatttcgt ccagcctgtc gccgacaaac tgcaggccgg gtttaccctc
     5221 gatgcgggca tgctccgcat aatcgacgcc gaacgtggcc tcgaagccgt cccagtaggt
     5281 aatcagttca aactcaatat cacccagtac ggcaaacatc agctgtactc cttacgttgt
     5341 ttctgagcca gcagacgctc cagcattttt tccagctcat gcaggctcat attcagggca
     5401 ccagtcagcc cggcaggcgc tgcggtttcc ttaccattga ggaaaaactg aggattaaag
     5461 ctgaccttga taccgccaga cgctccaccg ccagttgcag ttgcgccacg gcctgaatat
     5521 ccggcagcca tgatttccgg cgacgggata cggggaacat ccggtgtcat ttcagcggcc
     5581 aggcgctgcc cggccagtgc agcaagcgga gtggtccgtt gcaggccaat ggcggcaccc
     5641 tgcgcgatat tgtcaccaaa gcccataaac acgcgactcg gtgaatggat gcccagcttt
     5701 tcgctgaacc agtcactgat gctgtcaccc attccggtta cgctggtttt gagtgacgcc
     5761 catttgtttc tgatgccatt tatcaacccg tcaataagat gaccaccgaa gtcggtgaat
     5821 ttcgccggca gatcaacgcc gagatatttc agcgcagccg caaaggcttt ataaagcaga
     5881 ccagccggag accagttaac cagcagttta ccaattccca cgatgccgcc gttaaaggct
     5941 tcctgaatgt cagcccagcg ctgtttaaac cagctactga ctgcgcccca gttgcggtag
     6001 ataaggtaag ctgctgccgc gacggcggtg ataacgagac cgatgggatt catcagcagc
     6061 gcccggccaa tccagagaac ggcacgcccg gcgctcataa ttccgcgaac cagcccccct
     6121 gagagcacac cacccagtgt tctggctcct ctggcgacag caccaaagcc tgtcaccagc
     6181 cagcggagtt taccgccttc ccccagtgcg agcgtcagac gaagccagtt ggcccgaagt
     6241 aaaacagcat ttttccagac gcttacaaag ggggaaagaa ggagattcag cccaagcttg
     6301 agaccgatag tggccatcct gaaagcgagt aatgcgccca caacctttat ggtgctgctg
     6361 acgagctgcg gatttgccgc tatccatttg ccaacactgt ccattaaagg aataaatgtt
     6421 tcacccaact ggagcaaagc cggacgcaag gattgcccga tgctgatagc agaatcatta
     6481 aagccgatct gcattctgcg ccagcgacct tcaagcgtat cattctgctt tgcagcatcc
     6541 ttatccaggg tagaaattgc agccggagca ttcatttcct gcttactgga aaggtattta
     6601 tcccagccct gtcgcattga cagtaaatgg ttgacagtct gaatatcggt aaagacctca
     6661 gccagaccaa atgactccat gagtttctgc tgaccttcct gatcgcctct tgctcctgca
     6721 gctttccatt gctgcaagaa cgctttgcct ttactgtcga taaaacggtt ggcaatcatc
     6781 agtgaagctt cgtactgcga aaaaccctga gcgacgtaat tctgcattga cccctggtaa
     6841 tccaccccgg ctttagcata tttctggatg gtatctccgc ggcccattgc tgccagccag
     6901 ttggacatat tggtgaccgc ttcctctgca gagccactac ctttaccgac ctccagactg
     6961 gcaacaatct gggtaatcgc atcttttcca taaataccac gagcagcgaa ggctttagcc
     7021 ataccgggta atgcttttgc catatccttc agctcaaatg acccaagttt ggctcctgtt
     7081 gccgcaatac caaacgcctg ttcaagttct ttcgcatcag tgattctgag tgcatcgctg
     7141 aaggcataag tcattttggc aaggtcggtc atatcggctt tggttgctgt agcggtcttt
     7201 ccaagcatct ctgcaaacgt tgctgcccgt tcgggggcca taccatcagc aactaattgt
     7261 ccgactcccc ctaacagaga ctcctgcagt tggttaacct tcagcgaggc ttgtctgata
     7321 gcctggccaa ttgcacgttc ctgttttgca tccaggtctc ctgtgacact gatatcccgc
     7381 aactgtgatt caaacgaggc atattgttta accgaggcca tgaccggtgc gcccagcgtt
     7441 ctgccaatag cataggtttc tgcaccctga ccatagagcg ccaggcggtt agccttcaac
     7501 gcatcaccgg tggctgatac tgctgacaga cggcgctgct gacgttcaat ttgctccatg
     7561 gtgcggctta cccgcagcaa ctcgctgttg agatgctgca tccgggaaga acccagttga
     7621 ccataacgtt ctgttgcccg ggttaaggca ttctggcgtt cctgcagacg gcgggaggta
     7681 tcaccaaggg aatcaagggc gcgtcgggtg ccactgacgg ctgagcggaa gctgctcccg
     7741 acaatgccgc caataatgac gccgactgaa aattcactgg ccacggtggc tatcctctga
     7801 aagcaaaaaa aacggaaggg aagtgtctga aacccatgca gaacagccgc gactggcggc
     7861 tgttaagtga tacgttgtta ctgattgtcg ccgaactcgc ttttgatttg ctcttcagcc
     7921 tgctccagcc acatctccag atcgtcagta tcgagggcat caatctcccc cggttgaaac
     7981 ctgaaccatc tcgccagcag gccctgcgcc tgcatcagtg tttttgtcgc tcttgcccag
     8041 cccagtgatt ttctgaaatc gtttctgcag ctccatatag tcggcaagat ccatgttatc
     8101 gaggtcttcc gggaggatac cggtgctacg ggcaatcagt ggttcgtccc agtctgccgg
     8161 gtctttgttg attttgcgca cctgcttcag gtcttttact gtcaggcgtt tcagttcaat
     8221 ctgttcaatt ctggtacctg cagcagtggt gaaaggataa gacagcgtaa aagtatcgga
     8281 ctgggtctgt gacatgatca tactcctttg taaattcaga gcagtatgtc tggcggtgga
     8341 cgtgacggat attaaagggg attaagaaga aggggccgga gcccctgtga tgtcagcaag
     8401 tgcgaaaacc cttgcagtta cgcaggaaag cgatgagaag cgcctttccc tcagatttgc
     8461 cggtgccgga gaaccactgg tcgggcggct tccatgcttc aatcaaatcg gccagtttgc
     8521 gggcctttga acgtgtgcag tcaatcgggt cattggtttt acgggtatta aagagggtct
     8581 ccacccccgg aatatcaagg agggtaaacc acgtaccatt tgacatgccc agtgacgcac
     8641 atcgccctcc tttgtcagtc agttcaacac tcaccgtcag cccccgatat tgattcgata
     8701 gtcagtcagt tgatcaacgc caccgacgcg gaagatgttg gccagatagt ccagttgcag
     8761 caactcttca ccatccagta cctgtctgat atacgtgcag gtgaagctac tggagaactc
     8821 ggcgttctcg tgctgtttga acgtccccag cgggttcttc ttgaacataa ttgtcaggaa
     8881 ggtgaccagc gggatttcgt cgatcagccc ctgcgagctg tagcgctgga cgctggagcg
     8941 acactgcagc gccagcgact tgtacgggtt cgcggcagac aacatcgcat cgcggtaaaa
     9001 gctgttccat ttgatttcgc cttccagttt gtcaaaacca gccgggagtt ccaccttacc
     9061 caccatcccc agtgccttgt gctcctgcat aatcatggag acatcgggga gtttaacttc
     9121 ctcagcccgt cccagcaggt tagtaccatc cagatagatg ttggcattcg tgattcggtt
     9181 tatctcaatc tttgacatca gttgccccct ttcagggtta acaggtattc cgaggtgatt
     9241 tcagtctcaa acgtcagtcg ctccagcggc ggtggtggcg tatatttgta gctcagcaac
     9301 aggtgcccgg cggccagctc cgtctccgga ttgcgggccg gatcaaacca gcaacggaag
     9361 cccagtaccg caccatcacc agtcattttg cgaccgtagg cgttgaccga ctccgtcagt
     9421 gcatcaatca gcgcctgagt aatcggcatg tcgatgtact gctggctgaa gtaacgaatg
     9481 gactcgttga tcacatcacc ggtgcggcga acgttctcaa agttacgcat atgggtgacc
     9541 gttggccatg ctgccgtccg gttaccccac agatgaaggc cgctgccgta actgctgaat
     9601 accgtggtga tcccctgttc gttaagcagg ttcacctcgc tctgcggatc gtcaatcatt
     9661 gccgacagct ggcgctccac gccggtgatc cccagaattt cctgattgga ggatgaccac
     9721 cagtaccctt tgtccaggtc gactttggca cgcaggcccg ccgcacgctg gctcagtggc
     9781 tccagacgct ccgtgttcgt caccgggtca tataccttca catgcgggta gcacaggcgg
     9841 acacggtcag agctggtatt aaagttaatg gtgccttccg ggccacgtcc cgccagagcc
     9901 tgcgcaaaag tggtaccaac cggcgcatca atataggtta ctgctcccag tttctcagcc
     9961 atggcgataa gctcaaccga gacgctgttc tgggtgcaga ataccggagc aatcaggatt
    10021 ttggcgaagt agccaaacag gttaaaactg tcgttaagca gcttcatgcc ggtacggttg
    10081 cctgcagcgt taacggtacc gatgatatca gccggggtga ctttggtcgg atcagcatag
    10141 ttatagctgg ccttcaccgt tgcatctgca gcaatgcttt tacccaggtt agtaatcacc
    10201 ccggtctgtg catcaagcga gtagtcctga ccttcaacat aaggctgacc gttgctgtcc
    10261 ggtttcagta ccagctgcgc gaccaccgga ttagccagcc gggctctgcc tgtcgccttg
    10321 tcgaacgaca cattctcact gaccacagcg attttatgca cagacggatc gagtacgtta
    10381 atgaccagaa cggtgcctgc accatggtca taaatcgcat ccagcgcctg cggaatggta
    10441 aagccggtga actggctgcc aaatgccgca gcgtctttct cagacaggca ctgtaccagc
    10501 gtattgacat cccccatcgg ggcggtacca atcaggccaa taacggcaga tttcaccgtt
    10561 ttaaccgggc gggctccgtt ttccacctca atggtttcga cgccatgcag atagttagct
    10621 gccatgggag tcctccgttt tcacttcgct gtcactgctg cttctgcgct ttggtgactg
    10681 cacagccggt gtgacggcgg gtttagtatc ttctggtacc ggcgtcagat gcttcagcgc
    10741 caccagtacc ttcacgtagt catgctcctc cggcagggaa accgtcttcc ccggccagag
    10801 caggatttcg gttccgtccg acagcgtgac gccgctggcc gggccggaat agcggtattc
    10861 tttcatcact cgctttcctc atagttcact tcggttaaca gcgggccgga cggtaaatcg
    10921 ctgtcttcga taaagacgct ttcagtcgcg aagtcgaggg cgtattgcca cagccccctg
    10981 acttcaccga taaacacctc gcgggtcagc cagatacggc ggcggcagcc gggcggggtg
    11041 tggccgccga gaatgcggcg gacagcatcc aggacattaa tcgccccttt tttaccgttg
    11101 agctggcgga agaccaccgt gacgcagagc tggatagtct gagactggat caccgcaccg
    11161 gtatcatccg gcctgtcaaa gcgcgaaccg gcatagctca gcagcaacgc gccaaccgga
    11221 tggttcaggc gatattcagc cggtttctcc gggaagtact ccacctgcag ttgcggcagc
    11281 ttctcgcgta accgggccag taccgcatca aggacgggca gaacgttcat cagtatttct
    11341 ccagtaaacc gtcacgaccg ccgaaagtgg ccgggcggct gcgtacacga aactcgccag
    11401 gctcaggcac atctttctga gtggacggca gccccagcgt gagcctgtta tcacgtaact
    11461 ccctgagttg ccgcagcgct tctttgtggt catccttcac cgtatccggg aggtcacctt
    11521 ccgggcggcg ggcgtagagc cggtaacgga ccagcgtgat ggcaatgtcc cgcagaacag
    11581 tcggtatctc tgccagtggc aggatatagc gtccgcgcag atgggcatca atcagctcgt
    11641 cggcatagcg gatacagctg tccaccacac gggtattcac tgttgcaggc gagtcgaagt
    11701 ccatctcttc actggtgagc tcgatcagcg ttcgttccgg cacctgcgca agcaaatcct
    11761 ccagggtgca gtacatgtca caccccgcgc aggatacgaa tgacgtcgcc ttcacccccg
    11821 gcttcatcaa gtgcaatacc acaggattta ccgtcgccgg actgcggcac ggctctggcc
    11881 tgagcatctg actgaacagc cacaccacgg ctgacagcgg ccccggcctc gacagcaata
    11941 atgcccagaa cgctcaccgg cgtgctgtcg ccggtaacag catccacttc ggcaaccccg
    12001 agcgctgcgg caccggcttt acagggggta ttatctgccc cgacaaaacg ctgctgtgcc
    12061 agtgcggccc ctgccgttac ggttgtgatc agaatgacct gctgagtggt tcccataacg
    12121 cctccttatt tactgatacc ggtaatgaga tacccggcat cgccaccaac cacggcgact
    12181 ttgtagatat cggtataacg gcagtacttc accttgccgc cggctccgtc gtacttgtcg
    12241 gcaacaggca tccccttacg gcgcagggtg tagccgaagg acggctcgtt ctcgtccgcg
    12301 ctgtccgccc ccggctgcgg cttgccgacg taatgcagca tcagattgtc tccccagata
    12361 tccgtcggca cgctgtcctt atccattgcc gctttcatgg acggcaggga gacaggagca
    12421 ccgatgacga tctcttcgat ctgaaagagg tcctgcagga tctccgtggt gatgcgcttg
    12481 cgttcgttgg ctccgatggc tgcctgaatt gccgggtgga acttcagcag cgccatcacg
    12541 ccggccccca tggtcatcag gttaggacgc agccccgtgg ccgtacggac cgcttccata
    12601 ccggcttcaa ttaccccgat ggggtccccc ttaccaccgg cccagcggtc gccggctgtc
    12661 agttttttaa cgtgcccggt acggtagacc ttttcatcct gagccagacg ggcggcgata
    12721 agttcacggc gcagattcac gccattcgtg gcgcgacgga tggccttgct ctcctcgtta
    12781 aacatggact ccgcctgttc gcgatagtcc actggcgcag ccagatcgtg ctcacccagc
    12841 accagatcaa gcgtgccggt tttctcacgg accagaacat tgctgtccgc cccgacggca
    12901 cgctcggtgt catattccac aaaggcggtt ttcccgaagg tcggcacacg cacgccttcc
    12961 ttgtccgtca gcacgacggg gaaaatacgt tcgccaatga atgcggcatt tttatagcct
    13021 cgggcgatac tggtcagtac cggatcaacg acacgtttac cttttaagta atcagacatg
    13081 ctctctcctt aaattacagg cagcgtgcga cagcagcctc atagctgatg ccttcttttt
    13141 tggacagggc cactgctttc tgatgcaggg ccagacgctc aggatcggct tccgcaaact
    13201 ccgccacatc caccttcacc gcgtcgccga cacgatcctt tgtggcctgt tcggcgaagt
    13261 tcatcaccgg ctccccgtcg gagagcaatg aacggaaggc ggtggccagc ggtgtgcggc
    13321 tttccccctc agcaaactcc accggcttgt cgccaccggc gacggcatcc agcagggcaa
    13381 ccaccacgga ggaggcgcgg ggagccagac gcccctctgc gaccagtttt tctgcaaagg
    13441 ccacattgtc cttatgcagt tgctcctgtc tgacctgtgc atcacgcgca tcgcgatcag
    13501 cagcctgctg cttcaggcgg cggttctcct cctgaagggc ttcaatctct tcttttgtca
    13561 tcgatgattc ctcgttactt gcggaagacg gccccgggcc tgtctcactg aattgtgcac
    13621 ctgctgcatc ctgcgacagt gtgtcgcggt acgcctcttc gcgcagactg ttgagctgcc
    13681 attccggcag gactttttct gcctcgtcca gactgaagcg ggcgatcaga aaatcgcgca
    13741 gctttcccca cagggaggca ttcgtgatgg cctgccagtc ggcgaactcc accacacctt
    13801 cttcctgctc actgaaggac acctgtttca gccctttgac ggaaggtggc tgtgccccga
    13861 gaaagcccac atggcgaagg tagagcacgc cgggcttcgg attggacggt gaatccggga
    13921 ggtagaaaga ggcggacact tttttgaatc gtccgtcggt gaccatctca gcaaactgcg
    13981 ggtccagctg ggcaggctct gccatcagat cgacgccgct gagcgacagg gctttcaccc
    14041 agccccacgc cgggtcttcc gttctgggat gaccaatcac gagtggtgct tcatggacgg
    14101 acgggtcata ggctttcacg caggcggcaa gatcgtctgg cgtgaacggc agttttttgc
    14161 cgtgcatatc ggtatgagta ccggctttaa aaatgtgaat ggctgacatt ttgctgtccc
    14221 gcgttatgtt gtcggagaca gtttgtgaga aatgcaggcc cggcgatttt aatctgcttt
    14281 agaaaacatc aggggagaag gacagggaaa gcaatgcggt gaaccggagg cggttataaa
    14341 acagaggctg taaagccttt ataaaggtaa tacagcccct cattcgctgg caatgataaa
    14401 tcacccacct gaagagagaa aactcagcga cgggccgctg attcaagatg gcggacaatg
    14461 gtatcgagga tggggattac cacttcaggc tgtagttctc catcccccgt caccggcagg
    14521 aacgggcggg ccggaagttc aacagactca ttacgccccg ttttaccccc gaactggtga
    14581 atggcaccgt aaacaacgtt ggtccccaca acagcctgcc ggtcgtcatg gtcggttgat
    14641 actgacccca tcagacgccc ggtatcctgc agtgtctgcc cgtcacgttc ttccgctgcc
    14701 agcgagggca tccaccccgg acgcccctca tcaagaaagt taaactgtgt ttccgccagc
    14761 agggttccgg cgattttgcg catcgcgggc tccatgtctg tggcagccag atccagcgca
    14821 cggaggctcc ggcgcaggga tttatcgtta atggtgatac tgaccaggtt atcggaagcc
    14881 attgttatcc tctcagttcc tgttgtgcca gtggctgaag cgtaccctga tagcgggcca
    14941 ggtcgggacg gtatgctgcc cccggtgcat aagaccagcc gacgtcggtg gtcaccttcg
    15001 tggtgccggt attaaaggtg gccacgttcc gcatttcgcc ggttttctct gagaccagtt
    15061 tcagttcctg gcccatggca gagccggagc tgataacctt caggccacgg gcacgtacat
    15121 ccgtcgcact cagggcaatc acactacagc ggcagcgcca gccgttcggc gggtaaaatg
    15181 cctgccagaa cgggtcatcc cagcgcagca ccagaccatg cagcgccaga tggctcctgc
    15241 gggtatggct gtcgttgatg ccggtataca tccagtacgg cctgtcgtcg acgttttcca
    15301 tctgttccgc ccaacgaccg gcgctgtaga gtacggacat attggtgcga aagatggtat
    15361 cgagccgcca cggactgccc tgctgaatgg tgaccggctt acccgttacc gggtcagtcg
    15421 tgtcacgtgg tccccaccat cccttacgct tcagcaccgg ctccagctcc tgccggaacc
    15481 agcgatcggt ttttccttca tcgacagcct gctgcagtgc cccgcgaata tcttccagga
    15541 tatccaggcg ggtcacttta gcaacggtaa aggcgcgggc atgggcctcc tgccacattt
    15601 cttcccagtc ccaggtaatc tgataccctt tggacttcag gtaactgact gcccgcttcg
    15661 ggggaagcgt catgcagtac gccagttcag ccgttgtcac gctcatgcag gcgtccccag
    15721 atatttgcca caaagagaat gcgggccagc cgttcctgca gatcgtccgt gttcatctga
    15781 gggtagagct ccgccagttc gcccagcagc tcagtcgggt taaccccgtt ttcgacccgc
    15841 ttaaacagag gtgccaggac gggttccagc gtgccattta acacacctcc gttcatcaga
    15901 atgtccagcg cgtcgtcaag ctgctgctga gcctgaatat cggcatcaat cgcctcggca
    15961 aatgacagcg gcagcatgtt attctggcgt tccgacggtg gtgtctcgtc aatatcgccg
    16021 tcctgcagct ggtactcacg cttaaagtat tgcggggtca gacgcagacc cgcccgggtg
    16081 agtttttcgt cgcgggtggc gcgggtgtca tcaatggtct cctgttccca catggcccag
    16141 accggacacg gcacatcgcc gaagttcagg gtgaccaccg ttctgataac ctgattcact
    16201 gctgcctgaa tgatgtccgc atccgcatcg cggatatcag ccgttacctc cagcccggcc
    16261 tgtgctgagg ccttgttact gttcgcttcc gtggtctgat tctgaccaag taatgcaatg
    16321 gagatctcac tgcgtgacag tgtgatcagc tcgcggaata cctcgctgct gtccgcctta
    16381 ccatccgcgg ctttgagttc gatgctgctg tcatcgggga tggcggccac cgcgtcctcc
    16441 accatctgct ccatggagtc cagcagtttt tcaatctctg catcatttgc acccctcggg
    16501 tgcttaccga tcacccacgg ggagccaaac ttttcggcaa agcggagcca gaatttcatc
    16561 ccgcctttct tgaaggcgac cggccagaag cacatggaca ggtccgggaa accgtaagga
    16621 ttgtcatacg aggcatcctg tgccggcacc acgaattttg acggtgacag cagctcaccc
    16681 tccacacccg catcacgcgc ccggaagcgc aggcagttgt ccgtatcaaa ctgaaaccac
    16741 tcaggcggtt tgccgacaat atccgtcact gcccacgccc tgaccgaacg gccccacatg
    16801 atttcacagg gctgataccc gtagagcacg gcatcactca tctcaccgat gatgcgggac
    16861 agatccagat cgtcgagcat gtcgcggatg aaacggaaga cccgggcaga agcgtgaccg
    16921 cgctccagtc cacgctccag tgatttgagc gctgctttac gtctgcggat acagccccca
    16981 accagcgggt cggtgcgcag ttcgcggtag atacggatat cccgtccctg agccttgaga
    17041 atgggatcag gattgggcag atacatgccc agtccgtaaa agtcgatcgc gcggctgcgg
    17101 gaggcaatct gcgcggtcag tgatttctga ggctcagaaa aagcaacaaa ttcatcgggt
    17161 gaaacccaga tacccctcgc catcagaatc cctccagcat acgggccgcc tgacgacgac
    17221 agcgtgagct tgccttcacc ggccctttgt taatttcacg gctggcgaaa tacgccagcg
    17281 ccagtgcgat ggctgaatcc ccgtggcgtt taccaccgtc agcctttgct tttgagcgtt
    17341 gctccggcac gcgggggaca ccgttcacca cctgaacggc ccgcaggtca tccagtgtgt
    17401 cttcatcctt tggtaagtcc accaggttac cgtcttccag tgcagctttg accggaggca
    17461 tatgctcccg gtaccagcct tcagttggca tcacctgctg aacccggctg gagccgtagc
    17521 gctgcatggc gtattcagcc agataggcac cattaccacg ggcatcaaac gctgcaccca
    17581 gcagaccggg caggccatcc atcagatacc aggtgatttg ctcctgctgt ctgaacggca
    17641 cgttacgcag ctccagtacg aatggcacgc gtcgtaccag gttcttctcc tgcagcaggg
    17701 gatagtccac cgacaaatca ccgctacggc caaagtcgcg ccccaggaaa gagcgggcat
    17761 cagcggggag tgcctccagc aagggtttca gatgctcatc aagccagtcc tgtgtctcgt
    17821 ggaagcgaac ctcatcagac agcagttcat aaccttcctg acaggtcaga cgcaataccg
    17881 gcgtatcagc ggacatgcgg gactctatca gggcacggga cagccaggcg ccgccaccgt
    17941 tggccggaat acagtcaagc tcttcggatg cgccggcagc gtagaatttg tacaccgacg
    18001 ccatccaggc ctgctcggat gcctctgacc attccttccc ggtgcgcaga caaacgcgcc
    18061 ggaacagccc ctcagatacg gcttcccgga aagtgatgcg atgtacgctg cctccctgac
    18121 gtccggcacg gatatccccg ataagcgtat tgaacggatt gtcgtcaccg tcatgggtgg
    18181 agataacgcg tacctttccc ccccagataa gcatcgccag cgccgctttc agcagttcgt
    18241 ccagttgctc atggaacgcc gcttcgtcga taacaataat accctgacgg ccacgcaggt
    18301 tagacgggcg gctggagagc gcaacaatac gaaagccgga gtcaggaaat ttgatggtgt
    18361 aagtcttgat gtgtttgtcg tcgtcgtcct cttcccagaa tccttcttca atttcactgg
    18421 ccgcatagtt gaatgcccgt gcccacattg cacacgcctg aatgtattcg acggtcatgt
    18481 cctggttata agcgatgtaa tacacattca tcccgcctgc tggcgcagaa gaggcggcgg
    18541 tcagtacgtt atcggatgcc tcagcccatg taataccggt acgacggctc ttttctatca
    18601 ccttaagcgg agaggtgtct gccacccagc gctgctggta aggcaacaga acgggagggg
    18661 catccagcgc cgaggtatca ggcaaaacgg gagcaaggtt attcctcccg tccatgggac
    18721 tcatcccttc ggggccgccg ccagcggcgt ttaaaatcac tccggatgat tttgtcatgt
    18781 ggcaatcccc agaatctcgc gacgaagcgc ctgtactgcg tcgcttgaca gtcccccctt
    18841 acgggcaatt ttctcggcgt tgctggctgc ctgctgcgct ctggcccgta cttcagactg
    18901 gaactttttg aggttgacgg acgcgcggga cagcgtagcc acattcttcg ccaccttcga
    18961 cagcagggcc acgcgttctt taggatcgac ttcgccttct tccgcctcct gcaactggac
    19021 aatactctcg aacagctcgg tctgaataag ggctatcaca gcctccgaac gcgcatcctg
    19081 atcgtctgct gcgccttcgg tcagcatgcg ggccgcttct gttgccgcac ggatagcacc
    19141 atagcggcgc tcaatcttct gtccatagcg atggatagcg gatttgctga taacgtaccc
    19201 ccgctcacgc agcagggact ccagctcgtt atacccgctg aagccggatt cagtcagcgc
    19261 ccgttcaagc cagcggcgca cgtcttccgg cagcttttct attgtgctgc gtctggccat
    19321 tattcactcc agtacttttc cgggcgggca atacccggac cacattccac ggtgtattcc
    19381 accaggtcta cgccgaggcg ggtcaggtca gcaaaccagt cgccagaagg ttttttctcc
    19441 agatcaacca ttttacggtc agccagataa tccagttcgc ggcgcagttc cagcggtgtg
    19501 gtgtccgggt agatggcacg ggacacatcc agcagcagcg tctcgctggc ggtgtaaggg
    19561 cgggtcttgt tcagggcaac cagcagactc cagcgcaggg attcgcggcg tacccgggta
    19621 atatcgacca ttattgacct ccggtattgc ggtactgctg taccacttcc agtttgttat
    19681 aaagcgcgtc cagtttggcc tcaatgactg tctggccacg gatataatcc tctcgacgga
    19741 cataattcag cggtaaatcc gctttaaatc gcataaattc tttttccagc tcgccccagt
    19801 tggaggcgga ttgttgcagg gcctgttcaa gggaggcgaa tcgtgccgcc tggcgttctt
    19861 ctgttttact gaacaaccat ttggcgagcc ctcccacaaa ccccatgaag gtgagcagaa
    19921 aactcactac cgtccagaat tcaacctgca gtgtcatttc tgtaatcctt cccgttcatc
    19981 cagtaacgcg tttatctggt tccgccagcg acgacattgt cctgcgttgt cgatgatgtt
    20041 ggcgagaacg tcacgctggg agacacccga atcgcgtaac cgggtgtcag tggtttcagg
    20101 ttgcccggtc gctgtgccag agcgggtgcc agcggcggca actgagtctg aatgaccggt
    20161 gtcgacggat gcattgtcat atccgagtgc ggcgttgtac tggcgcacga aaccgcgagt
    20221 aaacacgcac tcaatgggat ggctcttacc tttttcatca atccagcgct gtgtgacatc
    20281 gttaatttgc ccctgtagtt gtttattccg gctctccagt tgagcaatct gctcaagata
    20341 accggcttca gcccgctgcc cggcggccac ctgctcctga taccgtctgg cccaggcccg
    20401 cagcgcagca ttctcaagcg ttgcctgctc cgttttgtac gcgtcaaatg ctgactgcaa
    20461 ctgactgagc gcggtatcac cgtcacgctt tgcagagtca tgaccacttc tgtatcccat
    20521 ggcatacagg ccgaccagaa aggcattgat aagaatggcc agcagaatgc cgcgccacgg
    20581 cagcttttta accagatgcc acacaactgc agcctcccca tgtgagatat cgcggtgcca
    20641 gttcgcgcag gatgcgctgc ggataatggc ggttctcccg ccagctggcc gcattgcgtc
    20701 cggcattcac cgtggcgaca tgtccgaacc agcgggtgct gtccagacct ttctgtgatg
    20761 caagccgcct gtcccgttgt acccagccca gaccaccgtt atagcccgac aatgtcatgg
    20821 ccatacgctc gcagtcgttg gcggcgctga cgcgctgcca cagccagcgg tcatagctga
    20881 ccagcgcccg gatagcccat gcaggattaa acggctcacg attgctcagc atcggtatca
    20941 actggcttat ccagtcggca gtggcaggca tgaactgcgc cagtccctga gcgccagccg
    21001 gcgagaccac atcaggtcgc cagccgcttt cctgatgcag ttgcgcggcg aaatcggcca
    21061 ccggcgcaga cagtccccat tcaagccggg cattacggat cacatcatcg cgatactgca
    21121 gcgcagcctg cggaggctgc gctgcgcggg cctgactgaa gaagccgcca caccagagca
    21181 gccagacaat caccaggttg ccagcaagct gccaccagaa gctgtattta tcgttacgtg
    21241 gttctccgtg tctgatggcg gttacgccca gaccaaaggc gaacagaata atgagggtga
    21301 tttgaggcca gttcatggtc acagtcctgt tgccacagcc agacagaccg ctgcaacaat
    21361 cagtgcacgg cggattaacg cagcagaaaa tacaaggtga aggccggtct gcacagggaa
    21421 acgcccttca gccatcagtc tgtcgtcatg tttcaggtac tgaccgggac gggctttggg
    21481 gaagagcgaa cggtcaagcc agtaacccag cactgctgcc agcgtgatga gtgccagctt
    21541 gtagatcaca acaggcaact gctgtggcga gaccagagcg atgatgccca gcaacagcac
    21601 tgaggtcagc agccagccgc tgaggcgagg ttttttaaca gggggaatga attttttcag
    21661 gtttttcatg tgtgtctcct cgtttggtgg agacagcatc acaaatgtgg cgggatacgg
    21721 attttaaaca gcgttaatag tgaagatgta aacgtgcact gcatgatggc tttgaaagaa
    21781 cgaccagccc ggtacccgaa caccgggctg gccatcgccc cacaggaatg cgctgtgagc
    21841 cgacacgaaa cccctcttgg aattccatac gacgatacag agctgtcagc atctcaaatg
    21901 aaatcgccac gattaaacct cagtcatcca catttcccta aattcttcag gtacattacg
    21961 tagggtgata atatttgttt ccggatcata atcaatatag ccttcagttt tcccttcccg
    22021 gtcaaactta agttcccaat atttagactt gcctttaaaa gataccagag cccgaatgac
    22081 tcgaccatca ggaacgaagc catccgataa ctccaactct tcagcagcaa gtttaccaga
    22141 taactcctcg ggagcctggg gccaaatggc attaacaagg gtttcaagac taagtggttc
    22201 accagcctta cttagtgcat gtaagtgttc aaacgcactc ttaagaaatg catctttttc
    22261 agcgccgtca agttctttct ctgccgcaaa tgcttttaaa acgtcacgta acttttcaga
    22321 ctctcgtttg gcgattaaga catcattaca gcctaggaac tgtgtgcgtc ctgcatattt
    22381 tgcacaaata tcgtttataa ggcgctgaga ggcttcagta actagacctt cttcaggact
    22441 caatctctca gaagcgtctc catttgaaag tgagttgggg ctggcatacc ggacatctgt
    22501 gagaatgatg caagcatcga caaaatactt atccccggcg ctgaaaccaa atgtgccaac
    22561 gttggcacat ttgggaaaag ccaaactttt cgaattaatg acagaagacg acgaagagct
    22621 tgccgaactg gccgacggcg gcacagttgc cggcctgacg cttgacgacg ttgatcgcat
    22681 gtcagtacgc gaacttcgcc aggccctgcg cgaagcgcgc gaaaccaacg cagcacaaca
    22741 gcgcgtactc gccgataaaa atgaaaaaat tgattctctc tctaccagac tggaaaagaa
    22801 atcccgtatt cagccgcctg agcctgatga ggaggttaag aagctgcggg cggaagtgac
    22861 agcattagcg gttgaggcgg aatctgctat cgccgttcga ctgtccagcg cttttgagac
    22921 actgtgcgca tattgagctg aaaacatgat tgataccccc agagacttca tggcaggcct
    22981 ggtctgtcaa ctggaaagca cagcgcgtag cctgcgctcc acatttgacc tgccggacga
    23041 gccaacaggc aatgcagcgc cttcatggct gactgagccg acgccacaga ttaacgggct
    23101 ggaggcataa ccaatgaatg ctgccctgac tgaacgactg gtttatgtcg cccgcgcggc
    23161 acgtgacgcg gggcatggta aacgcggtgc aatatacgac gctgcctgtg ctgaacttgg
    23221 catgtcccgc gccactctgc tgcgcaggct gaaggaggtc tctgtgactg ataaacgcaa
    23281 aaaacgcgcc gatgccgggc gcagcgccct gacccgcgac gaagccgcgc tgatatctgc
    23341 cacactgcgt gaggccaccc gcaagaacgg taagcgtctc tattccatcg cggatgcagt
    23401 ggaaaccctg cgggctaacg gctttatctc cgcaggcaga acagatgaaa ccaccggtga
    23461 gtttttcccg ttgtccgaag atgccatcag ccgtgccctg cgtaactatg gcctgcaccc
    23521 ggaacaactg gatgcccctg caccatatac tgaagtggcc agtctgcatc ccaatcatgt
    23581 ctggcagatt gatgcctcgc tctgcacgct ttactacctg agcaatggac ataaagggct
    23641 gcaggtgatg gacagcgcga agttctacaa gaacaagccc gctaaccttg cccgtatcgc
    23701 cagtgaccgc gtgtggagtt acgagattac cgaccatgcc agcggctgga tttacgttga
    23761 gtatgtgacg ggggcggaat ccggtgagaa cctgtgttct gtgcttatca acgccatgca
    23821 ggagcgtggc ggcgcagacg tgttgcacgg tgtgccgaaa atactctatc tcgaccccgg
    23881 ctcggcaaac accgcgggta tgacgaaaaa catgtgtcgc tcactgggca ttgacctgat
    23941 agcgcacaag ccgcataacg cccgcgccac cggacaggtg gaaaaggcgc gtgacattat
    24001 cgaacgcaag ctggagccgg gtctgaagtt ccggccggtt cacagtctgg aagaactcaa
    24061 cgcgctggcc gcgaaatggc gcagccactt taacgccacg gctgttcaca gccgccacgg
    24121 taaaacccgc acggatatct ggctgaagat tactgctgag cagctgaaaa aagcgccttc
    24181 cgttgaggta tgtcgtgaac tggctgtggc ggcaccagaa ctccgcaaag tcacgccaaa
    24241 acttcgtgtc tcgttccggg gcactgaatt tgacgtatca acggtaccgg gcgtactggt
    24301 cggtgaaaaa ctgatgatta cccgtaaccc gtggcgcagc gatgtggcac aggtggttct
    24361 gaccggtgag gacggccacg agacgttctt cctggtcgaa gaggtcagaa agaacgagtt
    24421 tggctttgct gaaggcgcgg cggtatttgg cgaaagttac aaagccctgc cggaaacccc
    24481 ggcgcagatg gcggcaaaag aaaccgaagc gctggtcacc ggtacagaca acgccgcaga
    24541 tgcagctgcc gcacgcaagg cgaaggcgct gccgttcggc gggcggcttg acccgtataa
    24601 acatattgat gacgccacac ttccggcctg tataccgaag cgaggtcagg cctctgacgt
    24661 acgcggaccg cgcactgaac agcgtcccat gactcatgtg gaggccgcga aagccctgcg
    24721 cgggaagttc agcgccaacg gccttacctg gacgccggaa cattaccgcc agttaacggc
    24781 acagtatccg gacggcgtac cggaagccgc actggatgaa gtcatggcta cgctgaccac
    24841 gccggcccgc agcagcgtta tcagcattgt taacggcaac tgaggaggga aacatgctgg
    24901 tactgaagca gcaactgaaa gaggcccgta ttccacaggc ggtggtggcg agagctgtcg
    24961 atgtttctga ggccacgctg gcccagattg tgaatcataa cgcgtggccc cgcaccagcc
    25021 ccggagaagt gcgccggcgt cttgcgtcct ggctggaaag tcaggggatt gatacagcga
    25081 agagttttga tgctgtacag ggcgcggcca cgccccgtac agcgggtacc acagataaaa
    25141 cgagcctcag tgaggaagag aatatgttac tcaaaaaaca ggtgttattt ccagcaacca
    25201 aaaaagcgtt tggtcttttc cgtgacccgt tcgccgacga agccatgcag ggttctgatg
    25261 atgtgttcac cacaccagac attcgctacg tgcgtgaggc gttgtaccag acagcccgtc
    25321 atggtgggtt tatggccgtc atcggtgagt ccggtgcggg taaatccacg ctgcgccgtg
    25381 acctgactga acgtatcaac cgcgagaatg cgccagtgat tgttatcgag ccatacatca
    25441 tcgctatgga agacaacgat gtgaaaggga aaactctgaa ggcagcagcg attgccgaag
    25501 ccattatcag taccatcgca ccactggaaa gcatcagacg cagtcaggac gcccgctttc
    25561 gccagttgca tcgcgtcctg aaagacagca accaggcggg gttcagccac gttctggtga
    25621 ttgaggaggc tcacagtttg cccattccga cactgaaaca cctcaaacgc ttttttgagc
    25681 tggagtccgg tttcaaaaag ctgctgtcca tcgtgctgat tggccagccg gaactggcga
    25741 caaaactctc tgaacgcaac atggaagtcc gcgaagtcgt tcagcgctgt gaggtggtcg
    25801 aacttctgcc tctggacaat caccttgaag aatttctgac gttcaaactg caacgggccg
    25861 gtaaacaact gacggacatt atggacgcca gcgcagtgga tgccatacgt acccgcctga
    25921 gcaatccggg aagtcatcgt aaaaatatgg tcagcctgct gtatccgctg gccgtcagta
    25981 acctggtaat agccgccatg aatctggccg ctgaaatcgg ggttccacag gtcaacgctg
    26041 acgttgtcaa aggggtttaa taatgaaatc caccacaggt atcaaccagc aaatcagtaa
    26101 agtgcagtca gccattatgg cgcttaaggc gacgaacacg gatgtacaaa gcatcaccat
    26161 caggggtaac aaacctgtca tccgcgtttc caggagtgcg cattgcatgc gcatgcttga
    26221 gcagggaaag gcctgttatc tgtataccgg acatgaccac aggggatatt tccgtcaggg
    26281 cgttttcgaa ctgcacggct gtcgcgtcgt gtggccggaa tctttgtggt aatcagcaca
    26341 actggagaaa tcataaaaaa tggcaaaaag tacaaaaggt gcaaaacgta tcaaggccgc
    26401 agcagcactc tgggtgccgg ggacacgtga agaggtcatt gagggcatca gactgctcgg
    26461 tgacgcacac cgtgaactgg tcagggctga aacagaaatg aatgacgcca ttggcgatat
    26521 caccgcacgt tatgccccgc tcaccgagag cctgaaaaaa cgcatggccg aactgcagtc
    26581 cggtattcag acatggtgtg aggcacaccg tgatgaactg accggcaacg ggaaggtgaa
    26641 gtttgctaac ctcaccaccg gcgaggtgca gtggcgaaac cgcccgccgt cagtcagcat
    26701 tcgcggagcg gataatgtta ttgaactact gagacgtctg gggcttgagc gctttattcg
    26761 tgtaaaagag gaaataaata aagacgctat cctgaatgaa aaagaggccg tgaaaaatat
    26821 tcccggtatt tccattaaaa gcgacattga ggatttttc
//
LOCUS       DAJVBX010000035        26792 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.035, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000035 DAJVBX010000000
VERSION     DAJVBX010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 26792)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26792)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26792
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.035"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..726
                     /locus_tag="OPV72_001331"
     CDS             <1..726
                     /locus_tag="OPV72_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HCR9913685.1"
                     /translation="SATLLAGCKNGVNGNLIASSGMSAYKAATLSDADVKALSNNACK
                     QMDSENQLAGSKSKYTKRLSKIAKALGNNIDGTPVSYKVYMTSDINAWAMANGCVRVY
                     SGLMDLMTDNEIEGVLGHELGHVSLGHSRKAMQTAYATLAARDAISATSGVAAQLSQS
                     QLGDLAEGVINLAFSRSQESDADDFSYNLLKKRGINTQGLVTAFDKFAIMDAGHAKSL
                     MDSHPASADRAQHMRDRIAEDKK"
     gene            899..1582
                     /gene="cmk"
                     /locus_tag="OPV72_001332"
     CDS             899..1582
                     /gene="cmk"
                     /locus_tag="OPV72_001332"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HCR9913686.1"
                     /translation="MTAIAPVITIDGPSGAGKGTLCKAMAEALQWHLLDSGAIYRVLA
                     LAALHHHVDLASEDALVPLASHLDVRFVSTDGNLEVILEGEDVSGEIRTQEVANAASQ
                     VAAFPRVREALLRRQRAFREAPGLIADGRDMGTVVFPDAPVKIFLDASSEERAHRRML
                     QLQENGFSVNFERLLAEIKERDDRDRNRAVAPLVPAADALVLDSTRLSIEQVIEKALQ
                     YARQKLALA"
     gene            1696..3369
                     /gene="rpsA"
                     /locus_tag="OPV72_001333"
     CDS             1696..3369
                     /gene="rpsA"
                     /locus_tag="OPV72_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HCR9913687.1"
                     /translation="MTESFAQLFEESLKEIETRPGSIVRGVVVAIDKDVVLVDAGLKS
                     ESAIPAEQFKNAQGELEIQVGDEVDVALDAVEDGFGETLLSREKAKRHEAWITLEKAY
                     EDAETVTGVINGKVKGGFTVELNGIRAFLPGSLVDVRPVRDTLHLEGKELEFKVIKLD
                     QKRNNVVVSRRAVIESENSAERDQLLENLQEGMEVKGIVKNLTDYGAFVDLGGVDGLL
                     HITDMAWKRVKHPSEIVNVGDEINVKVLKFDRERTRVSLGLKQLGEDPWVAIAKRYPE
                     GTKLTGRVTNLTDYGCFVEIEEGVEGLVHVSEMDWTNKNIHPSKVVNVGDVVEVMVLD
                     IDEERRRISLGLKQCKSNPWQQFAETHNKGDRVEGKIKSITDFGIFIGLDGGIDGLVH
                     LSDISWNVAGEEAVREYKKGDEIAAVVLQVDAERERISLGVKQLAEDPFNNWVALNKK
                     GAIVTGKVTAVDAKGATVELADGVEGYLRASEASRDRVEDATLVLSVGDDVEAKFTGV
                     DRKNRAISLSVRAKDEADEKDAIATVNKQEDANFSNNAMAEAFKAAKGE"
     gene            3525..3809
                     /gene="ihfB"
                     /locus_tag="OPV72_001334"
     CDS             3525..3809
                     /gene="ihfB"
                     /locus_tag="OPV72_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006819309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integration host factor subunit beta"
                     /protein_id="HCR9913688.1"
                     /translation="MTKSELIERLATQQSHIPAKAVEDAVKEMLEHMASTLAQGERIE
                     IRGFGSFSLHYRAPRTGRNPKTGDKVELEGKYVPHFKPGKELRDRANIYG"
     gene            4039..6303
                     /locus_tag="OPV72_001335"
     CDS             4039..6303
                     /locus_tag="OPV72_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC family protein"
                     /protein_id="HCR9913689.1"
                     /translation="MKITTVSVCVVCGILPLMILPVLPDTWILAVLFCLACLLCLIPH
                     HYARYAALTLLFFMWGIFAARQAIWVGNVLPAATQEATVVITATDHMTTHYGRITHLH
                     GKPLFPAVGIVLHGQYLPTEVCAGQQWAMTLKVRAVHGQLNEGGFDSQRYALAQHQPL
                     TGRFLQAKAINPECSLRGRYLASLRATLAPYPWQQVILALGMGERGAVSQEVKAVMRD
                     TGTAHLMAISGLHIAFAALLAAGLIRGGQFFLPVRWIRWQTPLLGGILCAICYAWLTG
                     LQPPALRTVAALSVWGGLKLSGRQWSGWQVWCCCLAAIIFADPVAVISQSLWLSAFAV
                     AGLLFWYQWFPAPNGNFPRGLRWLLNLLHLQAGITLLLLPLQVALFHGISVTAMLANL
                     FAVPWVTFVTVPLILAGMILHLTGPFFLEEWVWYLTDRALAALFYLLNALPQGWVNID
                     NRWQWLTLLPWLTLIAWRLNVWRTWPAVCLCGLLLMSWPLWRPINASGWQVHMLDVGQ
                     GLAIAIVRGDKVILYDTGRAWPEGDSGQQVIIPWLRWHNLTPEGVILSHEHLDHRGGL
                     RSLQQVWPSMWIRSPLGWQGHLPCFRGEQWQWQGLTFQAHWPLRESADRGNNRSCVVK
                     VDDGVHSILLTGDIEAGAEQKMLSRYWRHLAATFIQVPHHGSNTSSSLPFIQRVHGEA
                     ALASASRYNAWRLPSRKVKQRYRQQAYQWFDTPHQGQISLLFSPQGWRIQGLRDQILP
                     RWYHQWFGVSEDNG"
     gene            6340..8088
                     /gene="msbA"
                     /locus_tag="OPV72_001336"
     CDS             6340..8088
                     /gene="msbA"
                     /locus_tag="OPV72_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid A ABC transporter ATP-binding
                     protein/permease MsbA"
                     /protein_id="HCR9913690.1"
                     /translation="MHNDKDLSTWQTFRRLWPTIAPFKAGLIVAGIALILNAASDTFM
                     LSLLKPLLDDGFGKTDRSVLLWMPLVVIGLMILRGITSYISSYCISWVSGKVVMTMRR
                     RLFGHMMGMPVAFFDKQSTGTLLSRITYDSEQVASSSSGALITVVREGASIIGLFIMM
                     FYYSWQLSIILVVLAPIVSIAIRVVSKRFRSISKNMQNTMGQVTTSAEQMLKGHKEVL
                     IFGGQEVETKRFDKVSNKMRLQGMKMVSASSISDPIIQLIASLALAFVLYAASFPSVM
                     DSLTAGTITVVFSSMIALMRPLKSLTNVNAQFQRGMAACQTLFAILDSEQEKDEGKRV
                     IDRATGDLEFRNVTFTYPGREVPALRNINLKIPAGKTVALVGRSGSGKSTIASLITRF
                     YDIDEGHILMDGHDLREYTLASLRNQVALVSQNVHLFNDTVANNIAYARTEEYSREQI
                     EEAARMAYAMDFINKMDNGLDTIIGENGVLLSGGQRQRIAIARALLRDSPILILDEAT
                     SALDTESERAIQAALDELQKNRTSLVIAHRLSTIEQADEIVVVEDGIIVERGTHSELL
                     AQHGVYAQLHKMQFGQ"
     gene            8085..9062
                     /gene="lpxK"
                     /locus_tag="OPV72_001337"
     CDS             8085..9062
                     /gene="lpxK"
                     /locus_tag="OPV72_001337"
                     /EC_number="2.7.1.130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetraacyldisaccharide 4'-kinase"
                     /protein_id="HCR9913691.1"
                     /translation="MIARIWSGESPLWRLLLPLSWLYGLVSGAIRLSYKLGLKRAWRA
                     PVPVVVVGNLTAGGNGKTPVVIWLVEKLQQRGVRVGVVSRGYGGKAAAYPLLLTPETT
                     TAEAGDEPVLIYQRTGAPVAVAPERAAAVKAILAAHNVQIIITDDGLQHYRLARDIEI
                     VVIDGVRRFGNGWWLPAGPMRERASRLKTVDAAIVNGGVARAGEIPMQLAPGLAVNLR
                     TGARCDVAQLSNIVAMAGIGHPPRFFATLEACGAHPQKCVPLADHQTLAPADVQALVG
                     EGQTLVMTEKDAVKCRAFAEDNWWFLPVDARLSGEQPDKLLEHITSLVR"
     gene            9106..10338
                     /locus_tag="OPV72_001338"
                     /pseudo
     CDS             9106..10338
                     /locus_tag="OPV72_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459961.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YcaQ family DNA glycosylase"
     gene            10390..10572
                     /gene="ycaR"
                     /locus_tag="OPV72_001339"
     CDS             10390..10572
                     /gene="ycaR"
                     /locus_tag="OPV72_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YcaR"
                     /protein_id="HCR9913692.1"
                     /translation="MDHRLLEIIACPVCNGKLWYNQEQQELICKLDNLAFPLRDGIPV
                     LLENEARALTSDESKS"
     gene            10569..11315
                     /gene="kdsB"
                     /locus_tag="OPV72_001340"
     CDS             10569..11315
                     /gene="kdsB"
                     /locus_tag="OPV72_001340"
                     /EC_number="2.7.7.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate cytidylyltransferase"
                     /protein_id="HCR9913693.1"
                     /translation="MSFVVIIPARFSSTRLPGKPLVDINGKPMIVHVLERARESGAER
                     IIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLAEVVEKCGFTDDTVIVNVQGDEP
                     MIPAVIIRQVAENLAQRQVGMATLAVPIHSAEEAFNPNAVKVVLDAEGYALYFSRATI
                     PWDRDRFAKSLETVGDTCLRHLGIYGYRAGFIRRYVSWQPSPLEHIEMLEQLRVLWYG
                     EKIHVAVAKAVPGTGVDTADDLERVRAEMR"
     gene            11526..12419
                     /locus_tag="OPV72_001341"
     CDS             11526..12419
                     /locus_tag="OPV72_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcbJ family phosphotransferase"
                     /protein_id="HCR9913694.1"
                     /translation="MEQLRAELSHLLGEKLSRIECVNEKADSALWSLYDSQGNPMPLM
                     ARSFTTPGVAQQLAWKTSMLARSGTVRMPVIYGVLTHEEHPGLDVLLLERLRGVPVEA
                     PARTPERWEQLKDQIVEGLLAWHRQDSRGCVGAVDHTQENIWPSWYRQRVEVLWTTLN
                     QFSNTGLTMQDKRILFRTREYLPSLFEGFNDNCVLVHGNFCLRSMLKDARSDQLLAMV
                     GPGLMLWAPREFELFRLMDNPLAEGLLWHYLQRAPVAESFIWRRWLYVLWDEVAQLVN
                     TGRFNRTNFDLAAKSLLPWLA"
     gene            complement(12399..13175)
                     /gene="elyC"
                     /locus_tag="OPV72_001342"
     CDS             complement(12399..13175)
                     /gene="elyC"
                     /locus_tag="OPV72_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope biogenesis factor ElyC"
                     /protein_id="HCR9913695.1"
                     /translation="MLFTLKKVIGGMLLPLPLMLLIIGIGLALLWFSRFQKTGKVFIS
                     VGWLALLLLSLQPVSDHLLRPIENRYPTWQGPQKVEYIVVLGGGYTWNPQWAPSSNLI
                     NNSLPRLAEGIRLWRANPGARLIFTGGVAKTNTVSTAEVGARVAQSLGVPRSDIITLD
                     KPKDTEEEAAAVKQAIGDAPFLLVTSASHLPRAMIFFQHAGLNPLPAPANQLAIDSPL
                     NPWERAIPSPVWLMHSDRAGYETLGRLWQWLKGISGKPGE"
     gene            13311..14114
                     /gene="cmoM"
                     /locus_tag="OPV72_001343"
     CDS             13311..14114
                     /gene="cmoM"
                     /locus_tag="OPV72_001343"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine 5-oxyacetic acid(34)
                     methyltransferase CmoM"
                     /protein_id="HCR9913696.1"
                     /translation="MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLEEIGGR
                     KLRVLDAGGGEGQTAIKMAERGHQVTLCDLSGEMIARARQAAEAKGVSKDMHFIQCPA
                     QDVASHLESPVDLILFHAVLEWVADPVGVLETLWSVLRPGGALSLMFYNANGLLMHNM
                     VAGNFDYVQAGMPKRKKRTLSPDYPRDPAQVYQWLEAIGWQITGKTGVRVFHDYLREK
                     HQQRDCYETLVELETRYCRQEPYISLGRYIHVTAIKSPALAADARITYE"
     gene            14107..15429
                     /gene="mukF"
                     /locus_tag="OPV72_001344"
     CDS             14107..15429
                     /gene="mukF"
                     /locus_tag="OPV72_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partition protein MukF"
                     /protein_id="HCR9913697.1"
                     /translation="MSEFSQTVPELVAWARKNDFSISLPVDRLSFLLAVATLNGERLD
                     GEMSEGELVDAFRHVSDAFEQTSETIGVRANNAINDMVRQRLLNRFTSEQAEGNAIYR
                     LTPLGIGITDYYIRQREFSTLRLSMQLSIVAGELKRAADAAAEGGDEFHWHRNVYAPL
                     KYSVAEIFDSIDLTQRIMDEQQQQVKDDIAQLLNKDWRAAISSCELLLSETSGTLREL
                     QDTLEAAGDKLQANLLRIQDATMTHDDLHFVDRLVFDLQSKLDRIISWGQQSIDLWIG
                     YDRHVHKFIRTAIDMDKNRIFAQRLRQSVQTYFDDPWALTYANADRLLDMRDEEMALR
                     DDEVTGELPPDLEYEEFNEIREQLAAIIEEQLAIYKTRQTPLDLGLVVREYLAQYPRA
                     RHFDVARIVIDQAVRLGVAQADFTGLPAKWQPINDYGAKVQAHVIDKY"
     gene            15410..16114
                     /gene="mukE"
                     /locus_tag="OPV72_001345"
     CDS             15410..16114
                     /gene="mukE"
                     /locus_tag="OPV72_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partition protein MukE"
                     /protein_id="HCR9913698.1"
                     /translation="MSLTNIEQVMPVKLAQALANPLFPALDSALRSGRHIGLDELDNH
                     AFLMDFQEYLEEFYARYNVELIRAPEGFFYLRPRSTTLIPRSVLSELDMMVGKILCYL
                     YLSPERLANEGIFTQQELYDELLTLADEAKLLKLVNNRSTGSDVDRQKLQEKVRSSLN
                     RLRRLGMVWFMGHDSSKFRITESVFRFGADVRAGDDPREAQRRLIRDGEAMPIENHLQ
                     LNDETEESQPDSGEEE"
     gene            16114..20580
                     /gene="mukB"
                     /locus_tag="OPV72_001346"
     CDS             16114..20580
                     /gene="mukB"
                     /locus_tag="OPV72_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partition protein MukB"
                     /protein_id="HCR9913699.1"
                     /translation="MIERGKFRSLTLINWNGFFARTFDLDELVTTLSGGNGAGKSTTM
                     AAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGKLKAGVCYSMLDTINSRHQRVVV
                     GVRLQQVAGRDRKVDIKPFAIQGLPMSVQPTQLVTETLNERQARVLSLAELKDKLDEM
                     EGVQFKQFNSITDYHSLMFDLGIIARRLRSASDRSKFYRLIEASLYGGISSAITRSLR
                     DYLLPENSGVRKAFQDMEAALRENRLTLEAIRVTQSDRDLFKHLISEATDYVAADYMR
                     HANERRVHLDQALAFRRELYTSRKQLAAEQYKHVDMARELGEHNGAEGSLEADYQAAS
                     DHLNLVQTALRQQEKIERYEADLEELQIRFEEQNEVVAEAAEMQDENEARAEAAELEV
                     DELKSQLADYQQALDVQQTRAIQYNQAISALARAKELCHLPDLTPESAAEWLDTFQAK
                     EQEATEKLLSLEQKMSVAQTAHSQFEQAYQLVAAINGPLARSEAWDVARELLRDGVNQ
                     RHLAEQVQPLRMRLSELEQRLREQQEAERLLAEFCKRQGKNFDIDELEALHQELEARI
                     ASLSESVSSASEQRMALRQEQEQLQSRIQHLMQRAPVWLAAQNSLNQLSEQCGEEFTS
                     SQEVTEYLQQLLEREREAIVERDEVGARKNAVDEEIERLSQPGGAEDQRLNALAERFG
                     GVLLSEIYDDVSLEDAPYFSALYGPSRHAIVVPDLSQIAEQLEGLTDCPEDLYLIEGD
                     PQSFDDSVFSVDELEKAVVVKIADRQWRYSRFPSLPIFGRAARENRIESLHAEREVLS
                     ERFATLSFDVQKTQRLHQAFSRFIGSHLSVAFEDDPEAEIRRLNGRRVELERALATHE
                     SDNQQQRLQFEQAKEGVSALNRLLPRLNLLADETLADRVDEIQERLDEAQEAARFVQQ
                     YGNQLAKLEPMVSVLQSDPEQFEQLKEDYAWSQQMQRDARQQAFALAEVVERRAHFSY
                     SDSAEMLSGNSDLNEKLRQRLEQAEAERTRAREALRSHAAQLSQYSQVLASLKSSYDT
                     KKELLNDLQRELQDIGVRADSGAEERARQRRDELHAQLSNNRSRRNQLEKALTFCEAE
                     MENLTRKLRKLERDYHEMREQVVTAKAGWCAVMRMVKDNGVERRLHRRELAYLSADEL
                     RSMSDKALGALRLAVADNEHLRDVLRLSEDPKRPERKIQFFVAVYQHLRERIRQDIIR
                     TDDPVEAIEQMEIELSRLTEELTSREQKLAISSRSVANIIRKTIQREQNRIRMLNQGL
                     QSVSFGQVNSVRLNVNVRETHATLLDVLSEQQEQHQDLFNSNRLTFSEALAKLYQRLN
                     PQIDMGQRTPQTIGEELLDYRNYLEMEVEVNRGSDGWLRAESGALSTGEAIGTGMSIL
                     VMVVQSWEDEARRLRGKDISPCRLLFLDEAARLDARSIATLFELCERLQMQLIIAAPE
                     NISPEKGTTYKLVRKVFQNTEHVHVVGLRGFAPQLPETLPGTQAEDTPSEAS"
     gene            20925..22772
                     /gene="ldtD"
                     /locus_tag="OPV72_001347"
     CDS             20925..22772
                     /gene="ldtD"
                     /locus_tag="OPV72_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HCR9913700.1"
                     /translation="MLLNKMCGRCLSAISLCLAVTFAPLFNAQADEPEMIPGDSAVAA
                     TGQAGPQKQSAATAILAGIQPLPEGVSAEKVRADLQSQLPSGYTPVYMSQLTLLYAAR
                     DMKPMWDNRDAVKAFQQQLAEVAIAGFQPQFTAWVALLTAPAVNGMARDVVLSDAMMG
                     YLHFIANIPVKGQRWLYSNKPYALATPPVSVINQWQIALEEGQLPMFVASLAPQHPQY
                     APMHDALLKLVADSRPWPQLTNTATLRPGQWSNDVPALREILQRTGMLDGGPKIALPG
                     DNTSDSAVVSPSAVVDETSVAQPVDEPTARRSKPAPAARAYDRELVEAVKRFQAWQGL
                     GADGVIGPATRNWLNMTPAQRAGVLALNIQRLRLLPAELSTGIMVNIPAYSLVYYQNG
                     NQVLASRVIVGRPDRKTPMMSSALNNVVVNPPWNVPPTLARKDILPKVWNDPGYLERH
                     GYTVMRGWNSKEAIDPWQVDWATITPSNLPFRFQQAPGAHNSLGRYKFNMPSSDAIYL
                     HDTPNHNLFQRDARALSSGCVRVNKASELANMLLQDAGWNDARISGALKQGDTRYVNI
                     RQNIPVNLYYLTAFVGADGRMQYRTDIYNYDLTARSSAQIVPKVEQLIR"
     gene            23032..23580
                     /locus_tag="OPV72_001348"
     CDS             23032..23580
                     /locus_tag="OPV72_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcbK family protein"
                     /protein_id="HCR9913701.1"
                     /translation="MDKFDANRRKLLALGGVALGAAILPSPAFATLSTPRPRILTLNN
                     LHTGESIKAEFFDGRAYIQDELAKLNHFFRDYRANKVRSIDPRLFDQLYRLQGLLGTR
                     KPVQLISGYRSLDTNNELRARSSGVAKKSYHTKGQAMDFHIEGVALSNIRKAALSMRA
                     GGVGYYPRSNFVHIDTGPARHW"
     gene            23608..24255
                     /locus_tag="OPV72_001349"
     CDS             23608..24255
                     /locus_tag="OPV72_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003035823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCR9913702.1"
                     /translation="MNYRIIPVTAFSQNCSLIWCEQTRLAALVDPGGDAEKIKQEVDA
                     SGVTLMQILLTHGHLDHVGAASELAQHYGVPVIGPEKEDEFWLQGLPAQSRMFGLDEC
                     QPLTPDRWLNDGDRVSVGNVTLQVLHCPGHTPGHVVFFDEQSQLLISGDVIFKGGVGR
                     SDFPRGDHTQLIDAIKRKLLPLGDDVTFIPGHGPLSTLGYERLHNSFLQDEMPVW"
     gene            complement(24317..25507)
                     /gene="aspC"
                     /locus_tag="OPV72_001350"
     CDS             complement(24317..25507)
                     /gene="aspC"
                     /locus_tag="OPV72_001350"
                     /EC_number="2.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009653304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate transaminase"
                     /protein_id="HCR9913703.1"
                     /translation="MFENITAAPADPILGLADLFRADDRPGKINLGIGVYKDETGKTP
                     VLTSVKKAEQYLLENETTKNYLGIDGIPEFARCTQELLFGKGSALINDKRARTAQTPG
                     GTGALRIAADFLAKNTPVKRVWVSNPSWPNHKSVFNAAGLEVREYAYYDAENHSLDFE
                     ALQASLSEAQAGDVVLFHGCCHNPTGIDPTLEQWQVLAELSVEKGWLPLFDFAYQGFA
                     RGLEEDAEGLRAFAALHKELIVASSYSKNFGLYNERVGACTLVAADAETVDRAFSQMK
                     SAIRANYSNPPAHGASIVATILSNDALRAIWEQELTDMRQRIQRMRQLFVNTLQEKGA
                     NRDFSFIIKQNGMFSFSGLTKDQVLRLREEFGVYAVASGRVNVAGMTPDNMAPLCEAI
                     VAVL"
     gene            complement(25692..26783)
                     /gene="ompF"
                     /locus_tag="OPV72_001351"
     CDS             complement(25692..26783)
                     /gene="ompF"
                     /locus_tag="OPV72_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpF"
                     /protein_id="HCR9913704.1"
                     /translation="MMKRKILAAVIPALLAAATANAAEIYNKDGNKLDLYGKAVGRHV
                     WTTTGDSKNADQTYAQIGFKGETQINTDLTGFGQWEYRTKADRAEGEQQNSNLVRLAF
                     AGLKYAEVGSIDYGRNYGIVYDVESYTDMAPYFSGETWGGAYTDNYMTSRAGGLLTYR
                     NSDFFGLVDGLSFGIQYQGKNQDNHSINSQNGDGVGYTMAYEFDGFGVTAAYSNSKRT
                     NDQQDRDGNGDRAESWAVGAKYDANNVYLAAVYAETRNMSIVENTVTDTVEMANKTQN
                     LEVVAQYQFDFGLRPAISYVQSKGKQLNGADGSADLAKYIQAGATYYFNKNMNVWVDY
                     RFNLLDENDYSSSYVGTDDQAAVGITYQF"
BASE COUNT         6099 a         6824 c         7704 g         6165 t
ORIGIN      
        1 tccgccacgc tactggcagg atgtaaaaat ggcgtgaatg gcaatttaat cgccagttcc
       61 ggcatgtcag cctacaaagc cgccacactg tccgatgcgg atgttaaagc attatctaat
      121 aatgcctgta aacaaatgga cagcgagaat caactggcag gttcgaaaag caaatacacc
      181 aaacgtctga gtaaaatcgc taaagcgctg ggtaacaaca ttgacggtac gccggttagc
      241 tataaagtct atatgaccag cgatatcaac gcatgggcga tggcgaacgg ttgcgttcgc
      301 gtatactccg gcctgatgga tctgatgacc gataatgaaa ttgaaggcgt actgggccat
      361 gaactgggcc atgtctcttt agggcactcc cgcaaggcaa tgcagaccgc ctatgccacg
      421 ctggcggctc gcgatgcgat ttccgccacc agcggcgtcg cagcgcagct ttcccagtct
      481 caattgggcg atctggcgga aggcgtcatc aatttggcgt tttctcgcag tcaggagtcg
      541 gatgcggatg acttctctta caatctgctg aaaaaacgtg ggattaacac ccagggctta
      601 gtcacggcat tcgataaatt cgccataatg gacgcaggtc atgcaaaatc attgatggac
      661 tcccacccgg cctcagccga tcgcgcgcag catatgcgcg acagaattgc cgaagataaa
      721 aagtaaatca ttgtcatctt tcgggctggt ttctcgccag cccgctataa ttgcgcaatt
      781 attccgcatc tgattacaga caaaactggt ttttgcacgc aacgttaacg gtcgcgagcg
      841 ttggcgcgta taatgcgcgg cgtttacgtt aacggtacgc ctgtttaagg agataaagat
      901 gacggcaatt gccccggtaa taaccattga tggcccaagc ggtgcaggta aaggcacctt
      961 gtgcaaagca atggcggaag cattgcaatg gcatctgctg gattccggcg cgatataccg
     1021 cgtactggcg ctggcggcat tgcaccacca tgtcgatctc gcctctgaag atgcgctggt
     1081 gccgctggcg tcccatctgg acgtgcgttt cgtctcaacg gacggcaacc tggaagttat
     1141 cctggaaggc gaggacgtta gcggcgaaat tcgtacgcag gaagtcgcga acgcggcatc
     1201 ccaggtggcg gcattcccac gcgtgcgtga agcgcttctt cgccgccaac gcgcattccg
     1261 cgaagcgcct ggtttaatcg ccgatggacg cgatatgggg accgtggtct tcccggatgc
     1321 gccggtaaaa attttccttg acgcctcctc ggaggaacgt gcgcatcgac gtatgctaca
     1381 gttgcaggag aatggcttta gtgttaactt tgaacgcctt ttggccgaga tcaaggaacg
     1441 cgacgatcgc gatcgtaatc gcgctgtagc gccgttagtt cctgctgctg atgcattagt
     1501 tttggattct acccgattaa gcattgagca agtgattgaa aaagcgttac aatatgcgcg
     1561 ccaaaaattg gctctcgctt aaatgcgacc gaatttgtag tacccccgtt gcaaaggatt
     1621 gacagcgggt atgttaaaca accccatccg gcacggagcc aggtggacgt taaatatgaa
     1681 acctgaagat taaacatgac tgaatctttt gctcaactct ttgaagaatc cttaaaagaa
     1741 atcgaaaccc gcccgggttc catcgttcgt ggtgttgttg ttgctatcga caaagacgta
     1801 gtactggttg acgccggtct gaaatctgag tctgccattc cggctgagca gttcaaaaac
     1861 gcccagggcg aactggaaat ccaggttggt gacgaagttg acgttgctct ggatgcagta
     1921 gaagacggct tcggtgaaac tctgctctct cgtgagaaag ctaaacgtca cgaagcatgg
     1981 atcacgctgg aaaaagctta cgaagatgct gaaactgtta ccggtgttat caacggcaaa
     2041 gttaagggtg gcttcactgt tgagctgaac ggtattcgcg cgttcctgcc aggttctctg
     2101 gtagacgttc gtccggtgcg tgacactctg cacctggaag gcaaagagct tgaattcaaa
     2161 gtaatcaagc tggaccagaa acgtaacaac gttgtggttt ctcgtcgtgc cgttatcgaa
     2221 tccgaaaaca gcgcagaacg cgatcagctg ctggaaaacc tgcaggaagg catggaagtt
     2281 aaaggtatcg ttaagaacct cactgactac ggtgcattcg ttgatctggg cggcgttgac
     2341 ggcctgctgc acatcactga tatggcctgg aaacgcgtta agcatccgag cgaaatcgtg
     2401 aacgttggcg acgaaatcaa cgtgaaagtg ctgaaattcg accgcgagcg tacccgtgta
     2461 tccctgggcc tgaaacagct gggcgaagat ccgtgggttg ctatcgctaa acgttatccg
     2521 gaaggtacca aactgaccgg tcgcgtgacc aacctgaccg actacggctg cttcgttgaa
     2581 atcgaagaag gcgttgaagg cctggttcac gtttccgaaa tggactggac caacaaaaac
     2641 atccacccgt ccaaagtggt taacgttggc gacgtagtgg aagtgatggt tctggatatc
     2701 gacgaagaac gtcgtcgtat ctccttaggg ttgaagcagt gcaaatctaa cccgtggcag
     2761 cagttcgcag aaacccacaa caagggcgac cgcgttgaag gtaaaatcaa gtctatcact
     2821 gacttcggta tcttcatcgg cctggacggc ggcatcgacg gcctggttca cctgtctgac
     2881 atctcctgga acgttgcagg cgaagaagca gttcgtgaat acaaaaaagg cgacgaaatc
     2941 gctgcagttg ttctgcaggt tgacgcagaa cgtgaacgta tctccctggg cgttaaacag
     3001 ctcgcagaag atccgttcaa caactgggtt gctctgaaca agaaaggcgc tatcgtaacc
     3061 ggtaaagtca ctgcagttga cgctaaaggc gcaaccgtag aactggctga cggcgttgaa
     3121 ggttacctgc gtgcttctga agcatcccgt gaccgcgttg aagatgcgac tctggttctg
     3181 agcgttggcg acgacgttga agctaaattc accggcgttg atcgtaaaaa ccgcgcaatc
     3241 agcctgtctg ttcgtgcgaa agacgaagct gacgagaaag atgccatcgc aactgttaac
     3301 aagcaggaag atgcaaactt ctctaacaac gcaatggctg aagcattcaa agcagctaaa
     3361 ggcgagtaat cctctgaaac ttcgggcctt ttagtccgaa gtataacgag attacttgac
     3421 agattgcagg tttcggcctg taatcaagca ctaagggcgg ctacggccgc ccttaatcaa
     3481 tctcacggct gcagccaatt tgcctttaag gaaccggagg aatcatgacc aagtcagaat
     3541 tgattgaaag acttgcaacc cagcaatctc acattcccgc taaggcggtt gaagacgcgg
     3601 taaaagagat gctggagcat atggcctcga ctcttgcgca gggcgagcgt attgaaatcc
     3661 gcggtttcgg cagtttttct ttgcattacc gcgcgcctcg taccggacgt aaccccaaga
     3721 ccggcgataa agtggaactg gaaggaaaat acgttcctca ctttaaaccg ggtaaagaac
     3781 tgcgcgatcg cgccaatatt tacggttaag ttttaacgca aaacttgaac ccgaaaaaag
     3841 caccgtcagg gtgctttttt catttatacg ccgtcaggcg caaacgctat tcgaccgaaa
     3901 actggaaaac gtttcgcatt ttttgctgcg tcttacattt atcaggtaaa aaacctggaa
     3961 tccgcgccgt atagcacaaa atcccctcca gacaatggcg tcctgaacct gcacactttc
     4021 ccgcacaggg aggtgtctat gaagataacg acggtcagcg tatgcgtagt atgcggcata
     4081 cttccgctca tgatattgcc agtattacct gatacgtgga ttctcgcggt gctgttttgt
     4141 ctggcatgtt tgctttgcct cataccccat cactatgcgc gctacgcggc attaaccttg
     4201 ctctttttca tgtgggggat ttttgccgcc aggcaggcca tctgggtggg aaacgtcctg
     4261 cccgccgcga cgcaggaggc gacagtcgtc attactgcca ccgatcatat gaccactcat
     4321 tatgggcgaa ttacccattt gcatggaaag ccactctttc ctgctgtagg gattgtcctg
     4381 catggccagt acttacccac ggaagtgtgt gccggacagc agtgggcgat gacgctgaag
     4441 gtcagagcgg tacacggaca gcttaacgaa ggcggttttg atagccagcg ttacgcgctg
     4501 gcgcagcacc aaccgttgac cgggcgtttt ctacaggcta aagcgattaa ccctgagtgt
     4561 agcttgcgtg ggcgctatct tgcttcgctt cgcgctacgc ttgcgcctta tccgtggcag
     4621 caggttattc tggcgttggg aatgggggag cggggagcgg tgtcgcagga ggtgaaggcc
     4681 gttatgcgcg atacggggac tgcccatttg atggcgattt ccggcctgca tatcgctttt
     4741 gctgcgttat tggctgccgg attaatccgt ggcggacaat tctttttgcc ggtcagatgg
     4801 attcgttggc agacgccatt gctgggcggc attctttgcg cgatatgtta tgcctggctt
     4861 accggcttac aaccgcctgc gctgcgcacg gtggcggcac tgagcgtctg gggaggattg
     4921 aaattaagcg gacgacagtg gagcggctgg caagtctggt gctgctgtct ggccgcgatt
     4981 attttcgccg atcctgtggc ggttatatca caaagtcttt ggctgtcagc atttgcggtt
     5041 gccggcctgt tattctggta tcagtggttt cctgcgccaa acggaaattt tccacgaggc
     5101 ttacgctggt tgcttaacct gcttcaccta caggcaggca ttacacttct gcttttgcct
     5161 ctccaggtgg cgctttttca tggcataagc gttaccgcaa tgctggcgaa tctttttgcc
     5221 gtaccttggg tcacatttgt gacggttcca ctcatcctgg cgggaatgat tctgcattta
     5281 accgggccgt tttttcttga agagtgggta tggtacctga ccgatcgcgc gttagccgcg
     5341 ctattttacc tgttgaatgc tttaccgcag ggctgggtga atattgataa ccgttggcag
     5401 tggctgacgc ttttaccctg gctaacgctt atcgcgtggc gattaaacgt ctggcgtacc
     5461 tggccggcgg tctgtttatg cgggttattg ttgatgagct ggccactctg gcggccgata
     5521 aacgccagcg gatggcaggt gcatatgctg gatgtcggtc aggggctggc gatagcgatc
     5581 gtcaggggcg ataaagtaat actctacgat accggtcggg catggccgga gggcgacagc
     5641 gggcaacagg ttattattcc ctggttgcgc tggcataatc tgacgccgga gggcgttatt
     5701 ttgagtcatg agcatctgga tcatcggggc gggctgcgtt cgctacagca ggtctggccg
     5761 tcaatgtgga ttcgcagccc gttaggctgg cagggacatt tgccctgttt tcgcggcgag
     5821 cagtggcaat ggcaggggct aacgtttcag gcgcactggc cgttacgcga aagtgccgat
     5881 cgaggaaata accgttcttg tgtggtcaaa gtggatgacg gtgtacatag catcctgctc
     5941 acgggcgata tcgaagcggg cgctgaacaa aaaatgctaa gtcgttactg gcgacatctt
     6001 gcggcgacgt ttatccaggt gccgcatcat ggtagtaata cgtcgtcgtc gttaccattt
     6061 attcagcgcg tacatggtga agcggcgctg gcgtccgcat cgcgctataa cgcatggcgg
     6121 ctgccgtccc gcaaggtaaa acagcgctac cgacagcagg cgtatcagtg gtttgataca
     6181 ccccaccagg ggcaaatttc gctgctgttt tctccgcagg gctggcgcat acaaggctta
     6241 cgggatcaaa ttttacctcg ctggtatcat cagtggtttg gcgtgtccga ggataacggg
     6301 tagaatatgc ggctatttca acaaatgctg gttttttgaa tgcataacga taaagatctc
     6361 tctacgtggc agaccttccg ccgactgtgg ccaaccatag cgccttttaa agcaggtctg
     6421 atcgtggcgg gcatagcgtt aattctcaac gcagccagcg ataccttcat gctatcgctc
     6481 ctcaagccat tactggatga tggtttcggt aaaacggatc gctcagtgtt gctgtggatg
     6541 ccgctggtgg ttattgggct gatgatatta cgaggcatca ctagctatat ctccagctac
     6601 tgtatttcat gggtgtcagg caaggtggta atgaccatgc gccgtcgcct gtttggccat
     6661 atgatgggaa tgcccgtcgc cttctttgat aaacagtcta ccggtacgct gctgtcgcgt
     6721 attacatacg attcagaaca ggttgcctct tcttcatctg gcgcgctgat taccgtggtg
     6781 cgtgaagggg catcgatcat cggattgttt attatgatgt tctattacag ctggcagctg
     6841 tcgatcatcc tggttgtttt agcgccgatt gtgtcgattg cgattcgcgt tgtctcaaag
     6901 cggttccgca gcatcagtaa aaatatgcag aacacgatgg gacaagtgac taccagcgct
     6961 gaacaaatgc tgaaaggaca caaagaggta ctgattttcg gcggtcagga agtcgaaact
     7021 aaacgctttg ataaagtcag caataagatg cgactgcaag gcatgaaaat ggtctctgcc
     7081 tcgtcaattt ccgatcctat cattcagctc attgcctcgc tggcgctggc gtttgttctc
     7141 tatgctgcga gcttcccaag cgtaatggat agcctgacgg cagggaccat cacggtggtg
     7201 ttctcctcca tgatcgcgct gatgcgtcca ttaaaatcgc tgacaaacgt taacgcgcag
     7261 ttccagcgtg ggatggcggc ttgtcagacg ttgtttgcga ttctggacag cgaacaggag
     7321 aaagatgaag gtaaacgtgt cattgaccgc gcgaccggcg atctcgaatt ccgcaatgtg
     7381 acgtttactt acccgggccg tgaagtgccg gcattgcgta acatcaattt gaaaattcct
     7441 gccgggaaaa ccgtggcgct ggtggggcgt tccggatcgg gtaaatcaac tatcgccagt
     7501 ctgatcaccc gtttctacga tattgatgaa ggacacatcc tgatggatgg tcacgatcta
     7561 cgcgaataca ctctggcctc tctacgtaat caggtggcgc tggtttcgca aaacgtgcat
     7621 ctgtttaacg acacggtcgc caataacatt gcttatgccc ggacggaaga atacagccgc
     7681 gagcagattg aagaggcggc gcgcatggcc tatgccatgg actttatcaa caagatggat
     7741 aatggtctgg ataccattat cggcgaaaac ggcgtactgc tttccggcgg tcagcgccag
     7801 cgtatcgcga ttgcccgcgc cttactgcgc gacagcccga ttctgatcct tgatgaagct
     7861 acgtccgcgc tggataccga gtccgaacgt gcgattcagg ccgcgttgga tgagctgcaa
     7921 aaaaaccgta cctctctggt gattgcgcac cgtctctcca ccatcgaaca ggcggatgag
     7981 atcgttgtag tcgaagacgg tattatcgtt gagcgcggca ctcatagcga gctgctggcg
     8041 caacacggcg tttacgccca gctgcataag atgcaatttg gccaatgatt gcgcgtatct
     8101 ggtcgggtga atccccgcta tggcggttac tgctgccgct ctcctggctg tatggcctgg
     8161 tgagcggggc gattcgtctg agctataagc ttggtttgaa acgcgcctgg cgagcgccgg
     8221 taccggtggt tgtggtaggg aatcttacgg ctggcggtaa cggtaaaaca cccgtagtca
     8281 tttggctggt ggaaaagctg caacagcgtg gcgtgcgcgt gggggtcgtt tcccgcggct
     8341 acggcgggaa agctgccgct tatccgctgc tcctgacgcc tgagacgaca accgcagaag
     8401 cgggagatga accggtattg atttatcagc ggaccggcgc gcctgtcgcg gtggcgcctg
     8461 aacgcgccgc ggcggtgaaa gcgattctgg cggcgcataa tgtgcagatt attatcaccg
     8521 acgatgggtt gcagcattac cgactagcgc gagatattga aattgtggtg attgacgggg
     8581 tgcgccgttt tggcaacggc tggtggcttc ctgccggccc tatgcgcgaa cgcgccagtc
     8641 gcctgaaaac cgtggacgcc gctatcgtga atggcggcgt cgcccgggcg ggcgaaatcc
     8701 ccatgcagct agcgcctgga ctggcggtga acttacgtac gggagcgcgt tgcgatgtgg
     8761 cgcaactgag caatattgtg gcgatggcgg gcatcggtca tccgccgcgc tttttcgcca
     8821 cgctggaagc ctgtggcgcg catccgcaaa agtgcgtccc gctggccgat catcaaacgc
     8881 tcgcccctgc tgacgttcag gcgttggtcg gtgaagggca gaccctggta atgacggaaa
     8941 aagacgcggt gaaatgccgt gctttcgccg aagataactg gtggttctta ccggttgatg
     9001 cgcgtttgtc cggcgagcag cctgataagt tgcttgaaca tatcacctcg ctggttcgct
     9061 agcgtacccc aatgcagcgg cagtgatgaa tttatggagt catgaatgtc attgccgtac
     9121 ctttctcttt cccaggcccg ttgtcttcac cttgctgcgc aggggctatt gaaaaagccg
     9181 cgccgtaacg cgatgcctgg cgatgttctt gccgccatct cacgcatggc gttgctgcaa
     9241 attgatacca tcaatgttgt cgcacgtagc ccctatctgg tgctgtttag ccgtctcggt
     9301 tcgtacccgc aggcctggct ggatgaggcg ctgcgacgcg gcgagttaat agaatactgg
     9361 gcgcatgagg cctgtttctt accacgccgc gactttaaac ttatccgcca tcgtatgctg
     9421 tcgccggaaa aaatgggctg gaaatatcgc gcggcatgga tgcatgagca cgcggaagaa
     9481 atagaacagc tggtgcggca tattcaggag catggtccgg tgcgttctgc cgattttgaa
     9541 catgcgcaga aaggcgtcag cggctggtgg gaatggaaac cacataaacg ccaccttgag
     9601 ggtttattta ccgccggaaa agtcatggtt gttgagcggc gtaattttca acgtgtatat
     9661 gatttaacgc cccgtgtgat gccgcactgg gatgatgaac gcgatggact gtcacagccg
     9721 caggcggaaa gcctgatgct ggataatagc gcgcgcagtc tggggatttt ccgtgaacag
     9781 tggctggcgg attactaccg cctgaaacgt cctgacctga aaggatagcg ggagagccgg
     9841 gcggaacagc agcagattat tccggtcgag gtggaaacgt tggggcggat gtggcttcat
     9901 gccgatcttc tttcgcagct tgaaccggcg ctaaataacg ccttaaaggc gacccatagc
     9961 gcagtactgt cgcctttcga tcctgtggta tgggatcgta agcgggcagc gcagctcttc
    10021 gcattcgact accggctgga atgttatacg cccgcggcga agcgccagta cggttatttt
    10081 gtgctgccgc tattatacca gggccgttta gtcgggcgaa tggacgccaa aatgcaccgt
    10141 aaaacggggg tgcttgaggt tatctcgctg tatctggagg acgatattcg ccctggcgtt
    10201 agtctgcaaa aaggaatctg gcaggccatt agcgcgtttg ctgcctggca acgagcatcg
    10261 cgcgtgacgc tgggacaatg tccgccaggc ctgtttagcg ccatgcgtca tggctgggaa
    10321 atagaccctg caccataacc gattatgtta atattgaagg attcacaatc cggtccatct
    10381 ggaggaacta tggatcatcg tctgcttgaa atcatcgcct gcccggtatg taacggcaaa
    10441 ctctggtata accaggaaca gcaagaatta atttgcaaac tggataatct cgctttcccg
    10501 ttacgcgacg gcattcctgt attgctggaa aatgaagctc gcgccctgac atctgatgag
    10561 agtaaatcat gagtttcgtc gtcatcattc cggcccgttt ttcatctacc cgactgccag
    10621 gcaaaccatt agtggatatt aatggtaaac ccatgattgt tcatgtcctg gagcgggcgc
    10681 gcgaatctgg cgcggaacgc attattgtcg cgaccgatca tgaagacgtg gctcgtgcgg
    10741 tagaagcggc tggcggcgaa gtgtgcatga cgcgcgccga tcaccagtcc ggcaccgaac
    10801 ggttggcgga agtggtagag aagtgcggat tcaccgacga taccgttatt gtgaacgttc
    10861 agggcgatga gccgatgatc ccggcggtta ttattcgcca ggtcgcggaa aatctggcgc
    10921 agcgccaggt tggcatggcg acgctggcgg tgccgattca cagcgccgaa gaagcgttta
    10981 acccgaatgc ggtaaaagtc gtgctggatg ctgaaggcta tgcgctttac ttttcccggg
    11041 cgacgattcc ctgggatcgc gatcgctttg caaaaagtct ggaaacggta ggggatactt
    11101 gccttcgtca cctgggcatt tatggctatc gcgcgggatt tatccgccgt tacgtgagct
    11161 ggcaacccag cccgctggaa catattgaaa tgctggagca actccgtgtg ctgtggtacg
    11221 gcgaaaaaat tcatgtcgct gtcgccaaag cggtgcccgg cacgggcgta gacaccgccg
    11281 acgacctgga gcgcgtgcgc gctgaaatgc gttaacatga tcctgttcat gatcgtctta
    11341 gacggtcatg aacagcgcgg tatgatagcg caaagatgaa tactcacgtc tgctcatcag
    11401 tggcggcttt ctcgtaccgt tacgattttc ctcatttttc ttttcttccc ttgatctgat
    11461 acgggtgaca tctgtccata cgacgctcat tattaaagca gtagcactaa tgggggtaat
    11521 ctggaatgga acagttgcgg gccgaactca gtcatttgtt gggtgaaaaa cttagccgta
    11581 tagagtgcgt gaatgagaaa gcggattccg cattgtggtc attatatgac agccagggaa
    11641 atccgatgcc gctgatggcg cgaagtttta ccactcctgg cgttgcgcag caactggcat
    11701 ggaaaacctc aatgctggcg cgtagcggta cggtgaggat gccggtaatc tatggcgtat
    11761 tgacgcatga agagcatcct ggtctggatg tgctgctact ggaacgactg cgcggtgtgc
    11821 cggtcgaggc gccggcgcgc actccggaac gctgggaaca gctaaaagat cagattgtcg
    11881 aaggattgtt agcctggcat cggcaggata gccgcggttg cgtgggcgcc gtagaccata
    11941 ctcaggagaa tatctggcct tcctggtatc gtcagcgtgt ggaggtgctg tggacgacgc
    12001 taaatcagtt cagcaatacc ggcctgacga tgcaggacaa acgcattctg tttcgtacca
    12061 gagaatatct tccttcgtta tttgaagggt ttaacgacaa ctgcgtactg gtgcatggca
    12121 acttctgctt gcgcagtatg cttaaagacg cccgtagcga tcagcttctg gcgatggtcg
    12181 gccccgggct gatgctgtgg gcgccgagag aattcgaact gtttcgcctg atggataatc
    12241 cattggcgga gggattgctt tggcattatc tgcaacgcgc gccagtggcg gagtcattca
    12301 tctggcggcg ttggctctat gtgctgtggg acgaggttgc gcaattggtc aataccggac
    12361 gttttaaccg taccaatttt gatctggcgg cgaaatcatt actcccctgg cttgcctgat
    12421 atgcctttca gccattgcca aagtcgccct aatgtttcat acccagcgcg atcgctgtgc
    12481 atcagccaga ccggggacgg aattgcccgc tcccagggat tgagcggcga atcgatcgcc
    12541 aactgattcg ccggcgcggg aagcggattc agcccggcat gctgaaagaa aatcatcgca
    12601 cgcggcaaat gcgaggcgga ggttaccagc aggaaagggg cgtcgccgat ggcctgctta
    12661 acggcggcgg cttcttcttc cgtatctttt ggcttatcca gcgtaataat atcgctacgc
    12721 ggtacgccca gcgactgcgc cacccgcgcg ccgacttccg ccgtgcttac cgtattggtt
    12781 tttgctacgc cgccggtaaa aatcagcctg gctcccggat tcgcgcgcca cagccgaatg
    12841 ccttccgcca gccgcggcaa gctgttgtta attaaattag agctcggcgc ccactgcggg
    12901 ttccaggtat agccgccgcc gagaaccaca atatattcca ccttttgcgg accctgccag
    12961 gtagggtagc ggttttctat cggacgcagc aaatggtcag agacgggttg caggcttaat
    13021 agcaatagcg ccagccaacc tacgctgata aatacttttc cggtcttctg aaagcggcta
    13081 aaccagagca gcgccaggcc gatgccaatg atcagcaaca tcagcggaag cggcaataac
    13141 atgccgccaa tcactttctt tagcgtaaaa agcatccttt ttggttcctt ttttaaccat
    13201 atagcggagg attaacggtg atattacacc agacaggttc attctcgccg cggctgtgac
    13261 aaaatagcgg ttttatcaga taacgcctga gccagcctgt ggagagtccg atgcaggatc
    13321 gcaattttga tgacattgct gaaaagtttt cccgtaacat ttacggcacg accaaagggc
    13381 aactgcggca agccattctg tggcaagacc tggatcgcgt gctggaggag attggcgggc
    13441 ggaaactgcg ggtgctggat gccggcggcg gcgaagggca aacggcgatt aagatggcgg
    13501 aacgcggcca tcaggtgacg ttatgcgatc tgtctggcga aatgatcgcc cgcgcgcggc
    13561 aggcggccga ggcaaaaggt gtgagcaaag acatgcattt tatacaatgc ccggctcagg
    13621 acgtcgcttc gcatttggaa agcccggttg atctgatatt gtttcatgct gtgctggagt
    13681 gggtagccga tcctgtcggc gtattagaaa cgctctggtc agtattgcgc cctggcggcg
    13741 cgctgtcgtt gatgttctat aacgctaacg gtttgctgat gcacaatatg gtggcgggta
    13801 attttgacta cgtgcaggcg gggatgccta aacgcaagaa gcgcacgctg tcgcctgact
    13861 acccgcgcga ccccgcgcag gtgtaccagt ggctggaggc gattggctgg cagattaccg
    13921 gtaaaaccgg cgtgcgtgtg tttcatgatt atctgcgtga aaaacaccag cagcgtgact
    13981 gttatgagac cctggtcgaa ctggaaacgc gttattgccg ccaggagccg tatattagcc
    14041 ttgggcgcta cattcatgtc accgcgatta aaagcccggc gctagccgca gatgcaagga
    14101 taacctatga gtgaattttc ccagacagtc cccgaactgg ttgcctgggc cagaaaaaac
    14161 gacttttcca tctcgctgcc ggtagacaga ctttcctttc tgctggcggt cgccacgttg
    14221 aacggcgaac gccttgacgg cgagatgagt gaaggcgagc tggtggatgc attccgccat
    14281 gtgagtgatg cgtttgagca aaccagcgaa accatcggcg tgcgcgcgaa caacgcgatt
    14341 aacgatatgg tgcgtcaacg tctgctgaac cgctttacca gcgagcaggc ggaaggcaat
    14401 gcgatttacc gattaacccc gctcgggatt ggcatcaccg attactacat tcgtcaacgc
    14461 gaattctcta cgctgcgtct ttctatgcag ttgtcgattg tggccggcga attgaagcgc
    14521 gcggcggatg cggcagcgga ggggggcgat gagttccact ggcatcgcaa tgtttacgcg
    14581 ccattgaaat attcggtggc ggagattttc gacagtatcg atctcaccca gcgcattatg
    14641 gatgaacagc agcagcaggt gaaagacgat atcgcacaac tgctgaataa agactggcgg
    14701 gcggcgattt ccagctgtga gctgctgctt tccgaaacgt ccggtacgct gcgcgagttg
    14761 caggatacgc tggaggcggc gggcgataag ctgcaggcta acctgctgcg cattcaggat
    14821 gccacgatga cgcacgacga tctgcatttt gtcgacaggc tggtgtttga cttacaaagt
    14881 aaactcgacc gcattatcag ttggggtcag cagtctattg atttatggat cggctacgat
    14941 cgtcacgtgc ataaatttat ccgtaccgcg atcgatatgg ataaaaaccg tatcttcgcc
    15001 cagcggttgc gccagtccgt gcagacttat tttgacgatc cgtgggcgct aacctacgcg
    15061 aatgccgatc gtctgctgga tatgcgcgat gaagagatgg cgttgcgtga cgatgaagtc
    15121 accggggagt tgccgccgga tctggaatat gaagagttta acgagatccg cgagcagtta
    15181 gcggccatca ttgaagaaca gctggctatc tacaaaacca gacaaacgcc actggatctt
    15241 gggctggtgg tgcgcgagta tctggcgcaa tacccgcgcg cgcgtcattt cgacgtggcg
    15301 cgtattgtta tcgatcaagc ggtacgtctt ggcgtagcgc aagcagattt caccggactg
    15361 ccagccaaat ggcagccgat taatgattac ggagccaagg tacaggcgca tgtcattgac
    15421 aaatattgaa caagtgatgc cggttaagct ggcgcaggcg ctggcgaatc cgttatttcc
    15481 ggcgctggat agcgcattac gttcgggccg ccacatcggg ctggacgaac tggataatca
    15541 tgcctttctg atggattttc aggaatacct ggaagagttt tacgcgcgtt ataacgtgga
    15601 gttgattcgt gcgccggagg ggttctttta cctgcgtccg cgttctacca cgcttatccc
    15661 gcgctcggtg ttatccgaac tggatatgat ggtcggtaaa attctctgct acctctatct
    15721 tagcccggag cgtctggcca acgaagggat ctttactcag caggagttgt acgacgagct
    15781 gcttaccctt gcggacgaag ccaaactgct aaagctggtg aataaccgtt cgacgggatc
    15841 tgacgttgat cgtcagaaac tgcaggaaaa ggtgcgttct tctttaaacc gcctgcgtcg
    15901 tttgggcatg gtatggttta tgggccacga cagcagcaaa ttccgcatta ccgaatcggt
    15961 cttccgcttt ggcgcggatg tccgcgccgg cgacgatcct cgcgaggcgc agcgtcgtct
    16021 catccgcgac ggggaagcga tgcccattga aaaccatctg caacttaatg atgagaccga
    16081 agagagtcag ccggacagtg gagaggaaga ataatgattg aacgcggtaa atttcgctcg
    16141 ctaacgctga ttaactggaa cggttttttt gcccgcactt ttgacctgga tgaactggtc
    16201 acgacgttat ccgggggcaa cggcgccggg aaatccacga cgatggcggc gttcgtcacg
    16261 gcgctgatcc cggatctcac attactgcac tttcgtaaca ccacggaagc cggcgccacc
    16321 agcggttcgc gcgataaagg tctgcacggt aagctgaagg cgggtgtctg ttactccatg
    16381 ctcgacacca ttaattcccg ccatcagcgg gtggtggtcg gcgtgcgtct gcagcaggtc
    16441 gctgggcgcg atcgcaaagt ggacatcaaa ccgttcgcta ttcaggggct gccgatgtcg
    16501 gtacagccga cacaactggt gacggagaca ttaaacgaac gtcaggcgcg cgtactgtcg
    16561 cttgctgagc tgaaagacaa gcttgacgag atggaaggcg tgcagtttaa gcagtttaac
    16621 tccatcaccg attatcattc gctgatgttt gacttaggga ttatcgcccg tcgtctgcgt
    16681 tccgcttccg atcgtagtaa attctatcgt ttgatagagg cctcgctgta cggcgggatc
    16741 tccagcgcca ttacccgatc gctacgcgat tatttattgc cggaaaacag cggcgtgcgc
    16801 aaggcgttcc aggatatgga agcggcgctg cgcgagaacc gactcacgct ggaagcgatt
    16861 cgtgttaccc aatccgatcg cgatctgttt aagcatttga tcagcgaagc caccgattat
    16921 gtggcggcgg attatatgcg ccacgccaat gagcgtcggg ttcaccttga tcaggcgttg
    16981 gcgtttcgac gcgaactgta cacatcgcgc aaacaactgg cggcggagca gtacaagcac
    17041 gtcgatatgg cccgtgagtt gggcgaacat aacggcgccg aaggttctct tgaagcggat
    17101 taccaggcgg cgagcgatca cctgaatctg gtgcaaaccg cgctgcgcca gcaggaaaaa
    17161 attgaacgct acgaagcgga tcttgaagag ctgcagattc gattcgaaga gcaaaatgaa
    17221 gtggtggcgg aagccgccga aatgcaggac gaaaatgaag cgcgtgccga agccgccgag
    17281 ctggaagtcg atgaactcaa aagccagctt gcggattacc agcaggcgct ggatgtacag
    17341 caaacgcgcg cgattcagta taaccaggcg atatcagcgc ttgcccgcgc taaagaactt
    17401 tgccatctac cggatctaac gccggaaagc gccgccgaat ggctggatac tttccaggca
    17461 aaagagcagg aagctacgga aaaactgctg tcgttggaac aaaaaatgag cgtggcgcaa
    17521 accgcgcaca gccagtttga gcaggcttac cagctggtgg cggcgatcaa cggcccgctg
    17581 gcgcgtagcg aagcctggga cgtggcgcgc gagctgttac gggacggcgt gaaccagcgt
    17641 catctggcgg aacaggtaca gccgctgcgg atgcgcctga gcgaactgga acagcggctg
    17701 cgcgagcagc aagaggcgga acgtctgctg gcggagttct gtaagcgaca gggcaaaaat
    17761 tttgatattg acgaactgga agcgctgcat caggagctgg aagcccgcat cgcgtccttg
    17821 tctgagagcg tgtcgtcagc cagcgaacag cgtatggcct tgcgtcagga acaggaacag
    17881 ctgcaatccc gtatccagca tctgatgcaa cgcgctcctg tctggctggc ggcgcagaat
    17941 agcctgaacc agcttagcga acagtgcggc gaggagttta cgtccagcca ggaagtgacc
    18001 gaatacctgc aacagctact ggagcgtgag cgcgaagcca ttgtcgaacg cgacgaagtg
    18061 ggcgcacgta aaaatgcggt tgatgaagag atcgaacgtt taagccagcc gggcggtgcg
    18121 gaagatcagc gtttgaatgc gctggcggag cgttttggcg gggtactgct gtcggaaatc
    18181 tacgacgatg tcagtcttga agatgcgccg tacttctccg cactgtatgg cccgtcgcgc
    18241 catgcgatcg tcgtaccgga tttatcgcaa atagccgaac agcttgaagg tctgaccgac
    18301 tgcccggaag atctgtacct gatcgaaggc gatccgcagt cttttgatga cagcgtattc
    18361 agcgttgacg agctggaaaa ggcggtggtc gtgaaaattg ccgaccgtca gtggcgttat
    18421 tcgcgtttcc cgtcgctacc tatttttggc cgcgcggcgc gcgagaaccg tattgagagt
    18481 ctccatgcgg aacgggaagt gctttccgag cgctttgcca cgctctcgtt tgacgtgcag
    18541 aaaacccagc gtttgcacca ggcgttcagc cgttttatcg gtagccacct ttccgttgcc
    18601 tttgaggacg atccggaagc ggaaattcgc cgactgaacg ggcgtcgcgt cgagctggag
    18661 cgcgcgctgg cgacgcatga aagcgacaac cagcagcagc gccttcagtt tgagcaggcc
    18721 aaagagggcg tttccgcgct taaccgtttg ctgccgcggc tgaatttatt ggccgatgaa
    18781 acgctggccg atcgggtcga tgaaattcag gagcggttgg atgaggcgca ggaagcggcg
    18841 cgatttgtgc agcaatatgg caaccagtta gccaaactgg agccaatggt ttccgttctg
    18901 caaagcgatc cggaacagtt tgagcaatta aaagaagact atgcatggtc gcagcaaatg
    18961 cagcgcgacg cgcgccagca ggcttttgct ctggctgaag ttgtcgaacg tcgggcgcat
    19021 ttcagctatt ccgactcggc ggaaatgctg agcggcaaca gcgatctcaa cgaaaagctg
    19081 cgccagcggc tggagcaggc ggaagccgag cgtacccgcg cccgcgaagc gctgcgcagc
    19141 catgccgcgc agttaagtca gtacagccag gttctggcct cgctaaaaag ctcttacgac
    19201 acgaaaaaag agctgcttaa cgatttgcag cgcgaattac aggacattgg cgttcgcgcc
    19261 gacagcgggg cggaagagcg cgcccgccag cgtcgggatg aactgcacgc tcagttgagc
    19321 aataaccgtt cgcgtcgcaa tcagcttgag aaagcgctca ccttctgcga agcggagatg
    19381 gagaacctga cccgtaagct gcgcaagctg gagcgcgatt atcatgaaat gcgcgagcag
    19441 gtcgtgaccg cgaaagccgg ctggtgcgcg gtcatgcgga tggtgaaaga caatggcgtg
    19501 gaacgccgtc tgcaccgtcg tgagctggct tatctgtcgg cggatgaact gcgctccatg
    19561 tcggataagg cgttgggcgc gctgcgtctg gccgtcgcgg ataacgaaca tctgcgcgac
    19621 gtattgcgtc tgtcggaaga tccgaaacgc ccggaacgta aaatccagtt ctttgtggcc
    19681 gtttaccagc atctgcgcga gcgtattcgt caggatatta ttcgtaccga cgatccggtt
    19741 gaagccattg aacaaatgga gattgagctg agccgtctga cggaagagct gacatcgcgt
    19801 gagcaaaagc tggcgatcag ttcccgcagc gtggcaaaca tcatccgcaa aactatccag
    19861 cgtgagcaga accgtatccg tatgctgaac cagggtttgc aaagcgtctc gtttggccag
    19921 gtgaatagcg tgcggttaaa cgtcaacgtg cgtgaaacgc atgccacctt gctggatgtg
    19981 ctttcagaac agcaggagca gcatcaggat ctgtttaaca gcaatcgtct gaccttctcc
    20041 gaagcgctgg cgaaactgta ccagcgcctg aatccgcaga tcgatatggg tcaacgcacg
    20101 ccgcagacca tcggcgagga gttgctggac taccgtaact atctggaaat ggaagttgaa
    20161 gttaaccgtg ggtctgacgg ctggctgcgt gcggaatccg gcgcgctatc aacgggtgaa
    20221 gctatcggaa cagggatgtc aattctggtg atggtggtgc aaagctggga agacgaagcg
    20281 cgcagactgc gcgggaaaga tatttcgcca tgtcgcctgc tgttcctcga tgaagcggcg
    20341 cgtctggatg cgcgctctat cgccacgctg tttgaactat gcgaacgttt gcagatgcag
    20401 ctcatcatcg ctgcgccgga aaacatcagt ccggagaagg gcacgacgta taaactggtg
    20461 cgtaaagtgt ttcagaatac tgagcatgtt catgttgtcg ggctgcgtgg ctttgcgccg
    20521 cagcttccgg aaacgcttcc cggtacgcag gcggaagata cgccttcaga agcgagttaa
    20581 acacggcaga aacgatgaag tgcctgatgg cgcctcgctt atcaggcaag gccggataag
    20641 tcggttatgc cggcatccgg cataacaagt tctgctttat cattagcctg gggcggcgaa
    20701 agccgccttt ttctttatct gaaaaatctc tccgggtagt gtattttctt taaacttctt
    20761 tacattaggt taggcaaaaa cgtaacgaac tttatatact ggagttaagc ctgacgagtg
    20821 agcaggctga ctcgtcatac taaacaaaag cattggttga ggttgacccg cgctgcgggc
    20881 agcacagtca tgcggagtat gataacgaaa acagggggca agggatgttg cttaataaga
    20941 tgtgtggtcg ttgtctgtcg gcaatcagtt tatgcctggc cgtaacattc gctccactgt
    21001 tcaatgcgca ggccgatgag cctgaaatga tacctggcga tagcgccgtt gccgcgacgg
    21061 gtcaggctgg gccgcagaag caatccgccg cgacggcgat tctggccggg attcagccgc
    21121 tgccggaggg cgtttcagcc gagaaagttc gggctgattt acagtcgcag cttccttccg
    21181 gctatacgcc ggtctatatg agccagctga cattgctgta tgccgcgcgc gacatgaagc
    21241 ccatgtggga taatcgcgat gcggtgaaag ccttccagca acagttggcg gaggtggcga
    21301 tcgccggatt ccagccgcag tttaccgcct gggtggcatt gttgaccgct cccgccgtaa
    21361 acggtatggc gcgcgatgtt gtgttgtcag acgccatgat gggctatctc catttcattg
    21421 cgaatatccc cgtcaaaggc caacgctggc tatatagcaa caaaccttac gcattggcga
    21481 cgccgccagt ctcggtgatt aaccagtggc aaatcgcgct ggaagagggg cagttgccga
    21541 tgtttgtcgc cagcctggcg ccgcagcatc cacagtatgc gcccatgcat gacgcactgc
    21601 tgaagctggt ggcggactct cgcccgtggc cgcagttgac caataccgcg acgctgcgcc
    21661 cggggcaatg gagtaacgat gtgcctgcgc tgcgcgaaat attacagcgt acggggatgc
    21721 tggatggcgg tccaaagata gccttacccg gcgataacac ctctgatagt gccgtcgtca
    21781 gcccctccgc cgtagtcgac gaaacatcgg tggcgcagcc ggtcgacgaa ccaacggccc
    21841 gccgtagtaa gccggctccg gcggcacgcg cctacgatcg tgaactggtc gaggcggtaa
    21901 agcgttttca ggcatggcaa ggactggggg cggatggcgt cattggcccg gcgacgcgta
    21961 actggcttaa tatgaccccc gcgcaacgcg caggcgtact ggcactgaat atccaacgtt
    22021 tacgcctgct gccggcggaa ctctctaccg gtattatggt aaacattccc gcttattcgc
    22081 tggtctacta tcagaatggc aaccaggtgc tggcttcaag ggtgatcgtc gggcgtcccg
    22141 atcgtaaaac gccgatgatg agcagcgcgc tgaataatgt ggtggtgaac ccgccgtgga
    22201 acgttccgcc cacgcttgcg cgtaaagaca ttttaccgaa ggtgtggaat gacccaggct
    22261 atctggagcg ccatggctac accgtgatgc gcggctggaa cagcaaagaa gcgatcgatc
    22321 cgtggcaggt tgactgggcc accattacgc catcgaatct tccgttccgt ttccagcagg
    22381 cgccaggcgc gcacaattcg ctggggcgtt ataaatttaa tatgccgagt tcagatgcga
    22441 tctatctgca cgatacgcct aaccataatc tttttcagcg tgacgccagg gcgttaagtt
    22501 ccggctgcgt gcgggtcaat aaggcctctg aactggcgaa tatgcttttg caggatgctg
    22561 gctggaacga tgcgcggatc tctggcgccc tgaagcaagg cgacacgcgg tatgtcaata
    22621 tccggcagaa cattccagta aatctttact atctgaccgc gtttgtcggc gcagatggac
    22681 gtatgcaata tcgtacagat atttacaatt acgatctcac agcgcgatcc agcgcacaaa
    22741 ttgtgccaaa ggttgaacaa ttaatcaggt aaatgaagaa gttctggtaa atatgttgtc
    22801 ctaatgtttg gcttcaacgg ggcgtttcgc tgtagacccc cgttgtggct gggggagggc
    22861 catcttgacg cgggctttat cgccagttaa ggtgcctttc gtgcgccaga agtgcatata
    22921 caacaacctt taagtcgacc gggccgttca gaagtctgtg ccagccggta tcatgtctgc
    22981 ttaaaggtag aagtgtatta acgataacat tgacctgtag acctgattat catggacaaa
    23041 tttgacgcta atcgccgcaa gctgctggcg cttggtggtg tcgctctcgg cgccgccatc
    23101 ctgccctcgc cagcgtttgc cacactctcg accccacgcc cgcgcatttt gacgttaaac
    23161 aatctccata ccggagagtc aatcaaggcg gagtttttcg atggaagagc ctacattcag
    23221 gatgaattag caaagttaaa ccattttttc cgtgactatc gcgcgaataa agtccgatca
    23281 atcgatcccc gcctgtttga ccaactttac cgacttcagg ggctgttagg gacgcgtaaa
    23341 cctgtgcagc tcatctcagg ctaccgttct cttgatacca ataatgaatt acgcgcccgt
    23401 agcagcggcg tagcgaaaaa aagctaccat acaaaagggc aggcgatgga ttttcatatt
    23461 gagggcgtgg cgctgagcaa tattcgcaaa gcggcgttat ctatgcgcgc aggtggtgta
    23521 ggatattacc cacgtagtaa ctttgtgcat attgataccg ggccagcgcg gcactggtaa
    23581 tcagcgaggc ttaatcaaag gagcagtatg aactatcgta ttattccggt caccgcgttc
    23641 tcccagaact gttcattaat ctggtgcgaa caaacccggc tggcggcgct ggtcgatccg
    23701 ggcggcgacg cggaaaaaat taaacaggaa gtggacgcca gcggcgtgac gttgatgcaa
    23761 attttactca cgcatgggca tctcgatcat gtcggcgcgg cgagtgaact ggcgcagcat
    23821 tacggcgttc ctgttatcgg tccggaaaaa gaagatgagt tctggctgca aggactgccg
    23881 gcgcaaagcc gcatgtttgg tctggatgag tgtcagccgc tgacgcctga tcgctggctg
    23941 aacgacggcg atcgcgtcag cgtggggaat gtgacgttac aggtgttaca ttgtccggga
    24001 cacacgccgg gacacgtggt tttctttgat gaacagtcgc aactgctgat ctccggcgat
    24061 gtgattttca aaggtggcgt cgggcgcagc gattttcctc gcggcgatca cacccagttg
    24121 attgacgcca ttaagcgtaa attattgccg cttggcgatg atgtgacctt tattcctggc
    24181 cacggcccgc tctctacgct cggatacgag cgtctgcata attccttcct gcaagatgag
    24241 atgccggtct ggtaagcaga atgaaaaagc ctgcaatgtg caggcttttt tatcggtcac
    24301 gccagtcggc agctttttat agtaccgcga caatggcttc gcacagcggc gccatattat
    24361 ccggggtcat gcccgccacg ttcacgcgac cagaagccac ggcataaacg ccaaactctt
    24421 cacgcagacg cagcacctga tctttggtca gaccgctgaa tgagaacatc ccgttctgct
    24481 tgataataaa gctgaagtca cggttcgcgc ctttttcctg caaggtattc acgaacagtt
    24541 gacgcatacg ctgaatacgc tggcgcatgt ccgtcagttc ctgttcccag atagcgcgca
    24601 gggcgtcatt actcaggata gtcgcgacga tggacgcgcc gtgcgctggt gggttggagt
    24661 agttagcgcg aatggcggat ttcatctggc taaaagcgcg atccacggtt tccgcatcgg
    24721 cggcaacgag ggtgcaggcg ccgacgcgct cattatataa gccgaagttt ttggagtagg
    24781 agctggcgac aatgagctct ttatgcagcg cggcaaaggc gcgcagacct tccgcatctt
    24841 cttccaggcc gcgggcaaag ccctggtagg cgaaatcgaa tagcggcagc cacccttttt
    24901 caacggaaag ctcagccaga acctgccact gttccagagt agggtcaatg ccggttgggt
    24961 tatgacagca accgtggaac agaaccacat cgccggcctg tgcttcgctc aggctggctt
    25021 gtagcgcttc aaaatccagc gagtgatttt ccgcatcgta gtaagcgtac tcccgaactt
    25081 ccaggccggc agcgttaaac acgcttttgt ggttcggcca gctggggttg ctcacccaca
    25141 cccgttttac cggagtattt tttgccaaaa agtcggcggc aatgcgtaac gcgccggtac
    25201 cgcccggcgt ttgcgccgtg cgtgcgcgct tatcattaat cagcgcgctg cctttgccga
    25261 acagcagttc ctgagtgcag cgagcaaatt ccggaatccc gtcaatgccg agatagtttt
    25321 tcgtcgtttc attttccagt aaatactgct cggctttttt aacgctggtg agcaccggtg
    25381 ttttgccggt ttcatcttta tatacgccaa tgccaaggtt aattttccct ggacggtcat
    25441 cggcgcgaaa cagatcggcc aggcccaaaa tcgggtcggc aggagcggcg gttatgttct
    25501 caaacatgac gaggttccat tatagttaca gaagggaaat ccgctatcag gttaacggca
    25561 gatttacaaa atgccaaccg ttagcgctaa aaagcccgcc tgtttttgaa agacgcacat
    25621 tttctctaag agagataaaa aaacaggacc gaagtcctgt ttttgaggca taaaacaaag
    25681 gggtctgctg atcagaactg gtaagtaata ccgacagccg cctgatcgtc ggtgccaacg
    25741 tagctggagc tgtagtcgtt ttcgtccagc aggttgaaac ggtagtcaac ccatacgttc
    25801 atgtttttgt tgaagtagta agtcgcgccc gcctgaatat atttcgccag atcggccgag
    25861 ccgtcggcgc cgttcaactg cttaccttta ctctgcacat acgagattgc cggacgcagg
    25921 ccgaagtcaa actggtactg agcgaccact tccaggttct gcgttttgtt tgccatttcc
    25981 acggtatcgg taaccgtatt ttcaacaatg ctcatattgc gggtttcagc atatacggca
    26041 gccaggtaga cgttgtttgc atcatatttc gcgccaacgg cccacgattc tgcgcgatcg
    26101 ccattaccat cgcgatcctg ctgatcgtta gtacgcttgc tgttgctgta cgctgcggtg
    26161 acgccaaagc cgtcgaactc atatgccatg gtgtaaccta cgccatcgcc attctgagag
    26221 ttaatgctgt ggttgtcctg atttttaccc tgatactgga taccgaaaga gagaccgtcc
    26281 accagaccaa agaagtcaga gttacggtag gtcaacaaac cgccagcacg gctggtcatg
    26341 tagttatcgg tataggcgcc gccccaggtt tcgccggaga agtagggggc catatcggta
    26401 taggattcaa catcgtaaac gataccgtag ttacgaccat aatcgattga acccacttcc
    26461 gcgtatttca aacccgcgaa agccagacgt accagattcg agttctgctg ttcgccttca
    26521 gcgcggtctg ctttagtacg gtattcccac tgaccgaaac cggtcagatc ggtgttaatc
    26581 tgcgtttccc ctttaaaacc aatctgggca taagtctggt cggcattttt actatcgccg
    26641 gtcgttgtcc atacgtgacg acccacggct ttaccgtaca gatccagctt attaccatct
    26701 ttattataaa tttctgctgc gtttgcggtt gcagcagcca gcagggcagg gatcaccgct
    26761 gccaggattt tgcgcttcat cattatttat ta
//
LOCUS       DAJVBX010000036        26600 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.036, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000036 DAJVBX010000000
VERSION     DAJVBX010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 26600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26600
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.036"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(311..2587)
                     /gene="clpA"
                     /locus_tag="OPV72_001352"
     CDS             complement(311..2587)
                     /gene="clpA"
                     /locus_tag="OPV72_001352"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpA"
                     /protein_id="HCR9913705.1"
                     /translation="MLNQELELSLNMAFARAREHRHEFMTVEHLLLALLSNPSAREAL
                     EACSVDLVALRQELEAFIEQTTPVLPASEEERDTQPTLSFQRVLQRAVFHVQSSGRSE
                     VTGANVLVAIFSEQESQAAYLLRKHEVSRLDIVNFISHGTRKDEPSQSSDLGNQPAGD
                     EQAGGEERMENFTTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGV
                     GKTAIAEGLAWRIVQGDVPEVMADCTIYSLDIGSLLAGTKYRGDFEKRFKALLKQLEQ
                     DTNSILFIDEIHTIIGAGAASGGQVDAANLIKPLLSSGKIRVIGSTTYQEFSNIFEKD
                     RALARRFQKIDITEPSVEETVQIINGLKPKYEAHHDVRYTAKAVRAAVELAVKYINDR
                     HLPDKAIDVIDEVGARARLMPVSKRKKTVNVADIESVVARIARIPEKSVSQSDRDTLK
                     NLGDRLKMLVFGQDNAIEALTEAIKMSRAGLGHEHKPVGSFLFAGPTGVGKTEVTVQL
                     SKALGIELLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVIKHPHAVLLLDEI
                     EKAHPDVFNLLLQVMDNGTLTDNNGRKADFRNVVLVMTTNAGVRETERKSIGLIHQDN
                     STDAMGEIKKVFTPEFRNRLDNIIWFDHLSGEVIHQVVDKFIVELQAQLDQKGVSLEV
                     SQEARDWLAEKGYDRAMGARPMARVIQDNLKKPLANELLFGSLVDGGQVTVALDKEKN
                     ALTYDFQSAQKHKPEAAH"
     gene            complement(2618..2938)
                     /gene="clpS"
                     /locus_tag="OPV72_001353"
     CDS             complement(2618..2938)
                     /gene="clpS"
                     /locus_tag="OPV72_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005128368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease adapter ClpS"
                     /protein_id="HCR9913706.1"
                     /translation="MGKTNDWLDFDQLVEDSVRDALKPPSMYKVILVNDDYTPMEFVI
                     DVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCT
                     LEKA"
     gene            3262..3483
                     /gene="cspD"
                     /locus_tag="OPV72_001354"
     CDS             3262..3483
                     /gene="cspD"
                     /locus_tag="OPV72_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock-like protein CspD"
                     /protein_id="HCR9913707.1"
                     /translation="METGTVKWFNNAKGFGFICPEGGGEDIFAHYSTIQMDGYRTLKA
                     GQSVRFDVHQGPKGNHASVIVPIEAEAVA"
     gene            complement(3613..5559)
                     /gene="macB"
                     /locus_tag="OPV72_001355"
     CDS             complement(3613..5559)
                     /gene="macB"
                     /locus_tag="OPV72_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide ABC transporter ATP-binding
                     protein/permease MacB"
                     /protein_id="HCR9913708.1"
                     /translation="MTALLELCNVSRSYPSGEEQVAVLKDISLQIHAGEMVAIVGVSG
                     SGKSTLMNILGCLDKPTSGTYRVAGRDVSTLDPDALAQLRREHFGFIFQRYHLLSHLT
                     AAQNVEIPAVYAGIERKKRQARARELLLRLGLSDRVDYPPSQLSGGQQQRVSIARALM
                     NGGQVILADEPTGALDSHSGEEVMAILRQLRDRGHTVIIVTHDPLIAAQAERIIEIHD
                     GKIVHNPPAQEKKREQGVDAAVVNTAPGWRQFASSFREALSMAWLAMAANKMRTLLTM
                     LGIIIGIASVVSIVVVGDAAKQMVLADIRAMGTNTIDIHPGKDFGDDNPQYRQALKYD
                     DLVAIQKQPWVNSATPSVSKSLRLRYGNIDIAVNANGVSGDYFNVYGMSFREGNTFNA
                     VQQQDRAQVVVLDANTRRQLFPNKANVVGEVVLVGNMPVIVIGVAEEKPSMYGNSNLL
                     QVWLPYSTMSDRIMGQSWLNSITVRVKDGVDSDQAEQQLTRLLTLRHGKKDFFTWNMD
                     SVLKTAEKTTYTLQLFLTLVAVISLVVGGIGVMNIMLVSVTERTREIGIRMAVGARAS
                     DVLQQFLIEAVLVCLVGGALGISLSMFIAFMLQLFLPGWEIGFSLTALASAFLCSTFT
                     GILFGWLPARNAARLDPVDALARE"
     gene            complement(5556..6674)
                     /gene="macA"
                     /locus_tag="OPV72_001356"
     CDS             complement(5556..6674)
                     /gene="macA"
                     /locus_tag="OPV72_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide transporter subunit MacA"
                     /protein_id="HCR9913709.1"
                     /translation="MRAKGKKFKKRYLVIILILLVGGMVSWRMINAPLPTYQTLIVRP
                     GDLEQSVLATGKLDALRKVDVGAQVSGQLKTLLVSIGDNVKKDQLLGVIDPDQAENQI
                     KEVEATLMELNAERQQAAAELKLARVTLARQQQLAKTQAVSQQDLDTAATELAVKQAR
                     IGTIDAQIKRNRASLDTAKTNLEYTRIVAPMAGEVTQITTLQGQTVIAAQQAPNILTL
                     ADMSTMLVKAQVSEADVIHLRAGQKAWFTIAGDPQTRYEGVLKDILPTPEKINDAIFY
                     YARFEVPNPKRILRLDMTAQVYIQLMDVKNVLIIPLAALGEPVGGNRYKVALLRNGEK
                     REREVVIGERNDTDVEVVKGLEAGDEVIIGESRPGATP"
     gene            6820..7770
                     /locus_tag="OPV72_001357"
     CDS             6820..7770
                     /locus_tag="OPV72_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001519667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirK/YbjX family protein"
                     /protein_id="HCR9913710.1"
                     /translation="MTQLTDNTWYTSDYISPLQLFIRLTRGQLQPGKFWRKASFRRKF
                     LIRSLVMPRATSQLLTNLTQWPKLNTLLARQPRLPIRLHRPYMAVNIKRDFALDALCF
                     HYQQMRQLLSREQQVSYLSQYGLNLAKFEAKTGELFQLDLVSLVSLDKEGESTIVVRD
                     AQLRILAEITFTLCRFNQQRTLFIGGLQGAANDVPHEIIQQATKACHGLFPKRIVMEA
                     LCQFAQVFQAEKIIAVSNDAHVYRSWRYMDKKTQMHADYDAFWESLGGERIKGNYYTL
                     PLAIARKSEAEIASKKRAEYRRRYALLDSVVEQVPATFKR"
     gene            complement(7767..9425)
                     /locus_tag="OPV72_001358"
     CDS             complement(7767..9425)
                     /locus_tag="OPV72_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459916.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent endonuclease"
                     /protein_id="HCR9913711.1"
                     /translation="MILERVEIVGFRGINRLSLMLEQNNVLIGENAWGKSSLLDALTL
                     LLSPELDLYHFVREDFWFPPGDIKGREHHLHIILTFRETQPGRHRVRRYRALEACWSP
                     CEDDFHRIFYRLEGECGADGSVMTLRSFLNSDGQPLPVENINDQVRHLVRLMPVLRLR
                     DARFMRRIRNGTVPNVPDVEVTARQLDFLARELATRPQNLTDGQIRQGLSAMVQLLEH
                     YFSEQGAGQARHRLMRRRSQNEQRSWRYLDIINRMIDKPGSRSHRVILLGLFSTLLQA
                     KGTLRLHKDARPLLLVEDPETRLHPIMLSVAWQLLNLLPLQRIATTNSGELLSLTPVE
                     HVVRLVRESSRVAAWRLGTGGLSAEDGRRIAFHIRFNRASSLFARCWLLVEGETETWV
                     INELARQCGHHFDAEGIKVIEFAQSGLKPLVKFARRMGIEWHVLVDGDEAGKKYAATV
                     RSLLNNDREEEREHLTALPTLDMEHFMYRQGFADVFHRVAQLPLNVPMNTRKIITKAI
                     HRSSKPDLAIEVAMEAGRRGIDAVPPLFRKMFSRVVWLARGRAD"
     gene            9626..10525
                     /locus_tag="OPV72_001359"
     CDS             9626..10525
                     /locus_tag="OPV72_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine exporter LysO family protein"
                     /protein_id="HCR9913712.1"
                     /translation="MFSGLLIILVPLIVGYLIPLRHKAALQLINRLLSWIVYLILFFM
                     GISLAFLDNLASNLVAIFHYSAVSITIILLCNIAALLWLERILPWRHHHQQEKLPSRI
                     AMALESLQLCGVVVLGFIIGLSGLSVLQHATEASEYTLIFLLFLVGIQLRNSGMTLKQ
                     IVLNRRGMMVAVVVVASSLLGGVINAFILDLPLKTAMAMASGFGWYSLSGILLTESFG
                     PVIGSAAFFNDLARELLAIMLIPGLVRRSRSTALGLCGATSMDFTLPVLQRSGGVEIV
                     PAAIVHGFILSLLVPLLMAFFSA"
     gene            10669..12321
                     /gene="hcp"
                     /locus_tag="OPV72_001360"
                     /gene_synonym="priS"
     CDS             10669..12321
                     /gene="hcp"
                     /locus_tag="OPV72_001360"
                     /gene_synonym="priS"
                     /EC_number="1.7.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxylamine reductase"
                     /protein_id="HCR9913713.1"
                     /translation="MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIAALQG
                     LSAWAVKAREYGIINHDVDNFAPRAFFSTLTNVNFDSPRIVGYARDAIAMREALKAQC
                     LSVDANAHCDNPMADLQLVSDDLGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLK
                     GAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECAMEIGQMNFKVMSIL
                     DAGETTKYGHPTPTQVNVKATEGKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLP
                     AHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVGSYDDRIWTRS
                     IVGWPGVSHLEGDDFGPVIAQAQQMAGFPYSEIPHLITVGFGRQTLLGAADTLIDLVS
                     REKLRHIFLVGGCDGARGERNYFTDFVTSVPDDCLILTLACGKYRFNKLEFGDIEGLP
                     RLVDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVK
                     NIVTGPTAPGFFTPDLLAILNEKFGLRSVTTVEEDMKQLLSA"
     gene            12333..13301
                     /gene="hcr"
                     /locus_tag="OPV72_001361"
     CDS             12333..13301
                     /gene="hcr"
                     /locus_tag="OPV72_001361"
                     /EC_number="1.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidoreductase"
                     /protein_id="HCR9913714.1"
                     /translation="MTMPTSQCPWRMQVHHIRQETPDVWTIALLCHDYYPYRAGQYAL
                     VSVRNSAETLRAYTLSSTPGVSEYITLTVRRIEDGTGSQWLTHDIKRGDYIWLSDAMG
                     DFTCDDKTEDKFLLLAAGCGVTPIMSMRRWLAKYRPQADVQVIFNVRSPDDVIFADEW
                     RQYPVTLVAENHATEGFIAGRLTTELLQRVPDLASRTIMTCGPAPYMDFVEQGVKALG
                     VTHFFKEKFFTPVAETATSGLKFTKLQPAQEFYAPIGTTLLEALESNKVPVAAACRAG
                     VCGCCKTKVVSGDYTVSSTMTLSEAEIAEGYVLACSCHPQGDLVLA"
     gene            13459..15177
                     /gene="poxB"
                     /locus_tag="OPV72_001362"
     CDS             13459..15177
                     /gene="poxB"
                     /locus_tag="OPV72_001362"
                     /EC_number="1.2.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone-dependent pyruvate dehydrogenase"
                     /protein_id="HCR9913715.1"
                     /translation="MKQTVAAFIAKTLEQAGVKQIWGVTGDSLNGLSDSLNRMGTIEW
                     MPTRHEEVAAFAAGAQAQLTGELAVCAGSCGPGNLHLINGLFDCHRNHVPVLAIAAHI
                     PSSEIGSGYFQETHPQELFRECSHYCELVSSPEQIPQVLAIAMRKAVLNRGVSVVVLP
                     GDVALKPAPENAVTHWYHAPHPVVTPAEEELKKLAQLLRYSSNIALMCGSGCAGAHEE
                     LVALAAKLKAPIVHALRGKEHVEYDNPYDVGMTGLIGFSSGFHTMMNADTLILLGTQF
                     PYRAFYPSDAKIIQIDINPGSIGAHSKVDMALVGDIKATLRALLPLVEEKSNRKFLDK
                     ALEHYRDARKGLDDLAKLSDKAIHPQYLAQQISHFAADDAIFTCDVGTPTVWAARYLK
                     MNGKRRLLGSFNHGSMANAMPQALGAQATAPGRQVIAMCGDGGFSMLMGDFLSVVQMK
                     LPIKIVVFNNSVLGFVAMEMKAGGYLTDGTELHDTNFARIAEACGITGIRVEKAADVD
                     GALQRAFSIDGPVLVDVVVAKEELAIPPQIKLEQAKGFSLYMLRAIISGRGDEVIELA
                     KTNWLR"
     gene            15216..16217
                     /gene="ltaE"
                     /locus_tag="OPV72_001363"
     CDS             15216..16217
                     /gene="ltaE"
                     /locus_tag="OPV72_001363"
                     /EC_number="4.1.2.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low-specificity L-threonine aldolase"
                     /protein_id="HCR9913716.1"
                     /translation="MIDLRSDTVTRPGRAMLEAMMTAPVGDDVYGDAPTVNALQRYAA
                     DLSGKEAALFLPTGTQANLVALLSHCERGEEYIVGQGAHNYLYEAGGAAVLGSIQPQP
                     IDAAADGTLPLENVAAKIKADDIHFARTRLLSLENTHNGKVLPRAYLKDAWTFTRERG
                     LALHVDGARIFNAVVAYGCELKEITQYCDSFTICLSKGLGTPVGSLLVGNRDYIKRAT
                     RWRKMVGGGMRQAGILAAAGLYALKHNVARLQEDHDNAAWLAQQLREAGADVMRHETN
                     MLFVRVGEAQAAALGGYLRERNILINAAPIVRLVTHLDVSREQLADVVAHWRAFLAR"
     gene            16228..17661
                     /locus_tag="OPV72_001364"
     CDS             16228..17661
                     /locus_tag="OPV72_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2867 domain-containing protein"
                     /protein_id="HCR9913717.1"
                     /translation="MAQRILVLGASGYIGQHLVFALSQQGHQVRAAARRVERLEKHRL
                     ANVSCHKVDLHWPENLPALLRDIDTVYYLVHGMGEGGDFIAHERQAALNVRDALRQTP
                     VKQLIFLSSLQAPAHEQSDHLRARQLTADTLRDAGVPVTELRAGIIVGAGSAAFEVMR
                     DMVYNLPILTPPRWVRSRTTPIALENLLYYLVGLLEHPAHEHRILEAAGPQVLSYQQQ
                     FERFMAVSGKRRPLIPVPFPTRWISVWFLNVITSVPPTTAKALIQGLRHDLLADDAAL
                     KKLIPQTLITFDDAVRRTLKEEEKLVNSSDWGYDALAFARWRPEYGYFPKQAGFTAQT
                     PASLSALWQVVNRLGGKEGYFFGNILWQTRAAMDRLVGHKLAKGRPSHTLLKPGDTVD
                     SWKVIIVEPEKQLTLLFGMKAPGLGRLSFTLHDKGRYREIDVRAWWHPHGMPGLIYWL
                     LMIPAHLFIFRGMARRIARLAEQITEK"
     gene            17757..18770
                     /locus_tag="OPV72_001365"
     CDS             17757..18770
                     /locus_tag="OPV72_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HCR9913718.1"
                     /translation="MKVLVTGATSGLGRNAVEFLRNKGISVRATGRNEAMGKLLEKMG
                     AEFVHADLTELVSSQAKVMLAGIDTLWHCSSFTSPWGTQQAFDLANVRATRRLGEWAV
                     AWGVRNFIHISSPSLYFDYHHHRDIKEDFRPHRFANEFARSKAAGEEVINLLAQANPQ
                     TRFTVLRPQSLFGPHDKVFIPRLAHMMHHYGSVLLPHGGSALVDMTYYENAIHAMWLA
                     SQPGCDHLPSGRAYNITNGENRTLRSIVQKLIDELTIDCRIRSVPYPMLDMIARSMER
                     FGKKSAKEPPLTHYGVSKLNFDFTLDTTRAQDELGYQPIVTLDEGIERTAAWLRDHGN
                     LPR"
     gene            complement(18767..19597)
                     /locus_tag="OPV72_001366"
     CDS             complement(18767..19597)
                     /locus_tag="OPV72_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HCR9913719.1"
                     /translation="MKALLWLVGLALLLTGCASEKGIIDKEGYQLDTRHRAQAAYPRI
                     KVLVIHYTAENFDVSLATLTGRNVSSHYLIPATPPLYGGKPRIWQLVPEQDQAWHAGV
                     SFWRGATRLNDTSIGIELENRGWRMSGGVKSFAPFESAQIQALIPLAKDIIARYDIKP
                     QNVVAHADIAPQRKDDPGPRFPWRELAAQGIGAWPDAQRVAFYLAGRAPYTPVDTATV
                     LALLSRYGYEVKADMTAREQQRVIMAFQMHFRPAQWNGIADAETQAIAEALLEKYGQD
                     "
     gene            complement(19594..19917)
                     /locus_tag="OPV72_001367"
     CDS             complement(19594..19917)
                     /locus_tag="OPV72_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HCR9913720.1"
                     /translation="MQFSTTPTLEGQSIVEYCGVVTGEAILGANIFRDFFAGIRDIVG
                     GRSGAYEKELRKAREIAFQELGEQAKALGADAVVGIDIDYETVGKDGSMLMVSVSGTA
                     VKTRR"
     gene            20045..20560
                     /locus_tag="OPV72_001368"
     CDS             20045..20560
                     /locus_tag="OPV72_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCR9913721.1"
                     /translation="MRYSKLSLLIPCALLLSACTTVTPAYKDNGPRIGACVEGGPDSV
                     AQQFYDYRIQHHSNDIAALRPYLSDNLAKLLTDASRDTEHRQLMSGDMFSSRATLPDS
                     ANVASASTIPNRDARNIPLRVALKQGDQSWQDEVLMIHEGSCWVIDDVRYLGGDVHAP
                     AGTLRQSIENR"
     gene            20789..21517
                     /gene="artP"
                     /locus_tag="OPV72_001369"
     CDS             20789..21517
                     /gene="artP"
                     /locus_tag="OPV72_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001742668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter ATP-binding protein
                     ArtP"
                     /protein_id="HCR9913722.1"
                     /translation="MSIQLNGINCFYGAHQALFDITLDCPEGETLVLLGPSGAGKSSL
                     LRVLNLLEMPRSGTLTIAGNHFDFTKTPSDKAIRELRQNVGMVFQQYNLWPHLTVVQN
                     LIEAPCRVLGLTKDQALARAEKLLERLRLKPYSDRYPLHLSGGQQQRVAIARALMMEP
                     QVLLFDEPTAALDPEITAQIVSIIHELAETNITQVIVTHEVEVARKTASRVIYMENGH
                     IVEHGDAGCFAHPQTEAFKNYLSH"
     gene            21535..22266
                     /gene="artJ"
                     /locus_tag="OPV72_001370"
     CDS             21535..22266
                     /gene="artJ"
                     /locus_tag="OPV72_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter substrate-binding
                     protein"
                     /protein_id="HCR9913723.1"
                     /translation="MKKVLIAALIAGFSLSATAAQTIRFATEASYPPFESMDANNKIV
                     GFDVDLANALCKEIDASCTFTNQAFDSLIPSLKFRRFDAVMAGMDITPEREKQVLFTT
                     PYYDNSALFVGQQGKYTSVDQLKGKKVGVQNGTTHQKFIMDKHPEITTVPYDSYQNAK
                     LDLQNGRIDAVFGDTAVVTEWLKANPKLAPVGDKVTDKDYFGTGLGIAVRQGNTELQQ
                     KFNTALEKVKKDGTYETIYNKWFQK"
     gene            22273..22989
                     /gene="artQ"
                     /locus_tag="OPV72_001371"
     CDS             22273..22989
                     /gene="artQ"
                     /locus_tag="OPV72_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter permease ArtQ"
                     /protein_id="HCR9913724.1"
                     /translation="MNEFFPLASAAGMTVGLAVCALIIGLALAMFFAVWESVKWRPIA
                     WIGSALVTILRGLPEILVVLFIYFGSSQLLLTLSDGFTLHLGFTQIPVQMEIENFDVS
                     PFLCGVIALSLLYAAYASQTLRGALKAVPSGQWESGQALGLSKTAIFFRLVMPQMWRH
                     ALPGLGNQWLVLLKDTALVSLISVNDLMLQTKSIATRTQEPFNWYIIAAAIYLVITLI
                     SQYILKRIDLRATRFERRPD"
     gene            22989..23657
                     /gene="artM"
                     /locus_tag="OPV72_001372"
     CDS             22989..23657
                     /gene="artM"
                     /locus_tag="OPV72_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter permease ArtM"
                     /protein_id="HCR9913725.1"
                     /translation="MLEYLPELLKGLHTSLTLTVASIAVALVLALVFTIILTLKTPFV
                     VWLVRGYITLFTGTPLLVQIFLIYYGPGQFPTLQEYPLLWHLLSEPWLCALIALSLNS
                     AAYTTQLFYGAIRAIPEGQWQSCGALGMSKKDTLAILLPYAFKRALSSYSNEVVLVFK
                     STSLAYTITLMEVMGYSQLLYGRTYDVVVFGAAGVIYLVVNGLLTLMMRLIERKALAF
                     ERRN"
     gene            23894..24625
                     /gene="artJ"
                     /locus_tag="OPV72_001373"
     CDS             23894..24625
                     /gene="artJ"
                     /locus_tag="OPV72_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein ArtJ"
                     /protein_id="HCR9913726.1"
                     /translation="MKKLVLAALLASFATGSIAAEKINFGVSATYPPFESLDASNKIV
                     GFDIDLATALCKQMQAECTFTNHAFDSLIPALKFRKYDAVISGMDITPERSKQVAFSN
                     PYYANSALVIAKKDTYKTFTDLKGKRIGMENGTTHQKYLQDKHPEVKTVAYDSYQNAI
                     IDLKNGRIDGVFGDTAVVNEWLKTNPQLGPATEKVTDPQYFGTGLGIAVRPDNKALLE
                     KLNNALAAIKADGTYQKISDQWFPQ"
     gene            complement(24844..26331)
                     /locus_tag="OPV72_001374"
     CDS             complement(24844..26331)
                     /locus_tag="OPV72_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase"
                     /protein_id="HCR9913727.1"
                     /translation="MKAIILLFDSLNKNYLPPYGDLLTKAPNFQRLAAHAATFDNSYV
                     GSMPCMPARRELHTGRYNFLHREWGPLEPFDDSMPELLKKAGIYTHLISDHLHYWEDG
                     GGNYHNRYSSWDVVRGQEGDHWKASVGEPPIPEVLRVPQKQTGGGVSGLWRHDWANRE
                     YIQQEADFPQTKVFDAGCDFIHKNHAEDNWLLQVETFDPHEPFYTTEEYLSLYDDEWQ
                     GSHYDWPRGKVSESEEAIAHIRCRYRALVSMCDRNLGRILDLMDEHDLWRDTMLIVGT
                     DHGFLLGEHGWWAKNQMPYYNEVANNPLFIWDPRSAVCGARRQSLVQMIDWAPTLLDY
                     FQQPIPADMQGQPLAKVIASDEPVREGALFGVFSGHVNVTDGRYVYMRAAQPGREHDI
                     ANYTLMPIKMNARYDVDELGKLSLAPPFKFTKGLQVLRIPAREKYKGVNSFGHLLFDL
                     RDDPQQQHPIHDEAIEARMINLLIRLMKENDAPAEQYRRLGLDVV"
     gene            complement(26341..26550)
                     /locus_tag="OPV72_001375"
     CDS             complement(26341..26550)
                     /locus_tag="OPV72_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001669315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter IIB"
                     /protein_id="HCR9913728.1"
                     /translation="MEHTAAGEVGGFTDWADIYAISKKLLDVVSLDPKHGQYLIPIEN
                     IMDSESIGKQIYDVVEKNFPHLLNK"
BASE COUNT         6105 a         7430 c         6766 g         6299 t
ORIGIN      
        1 gagaaattca gcgatgttgg tttgatacag gtatgggata atcacagaag aattctttgt
       61 gctaagtgta agactactct tttcagagaa gaggattagt ttttttggca ttggtaacag
      121 cggcttcagc atcccttttc acgcagcggg tcgggctttt tttcgcattt gacccgtcga
      181 ttaccggatg atggcgcaat ttacaagcgc cttatccgcc taccgcgagc acaacaccat
      241 caggctaact attagccggc ataaaaaaac cgggcgctaa ggcccggttt gtacggcagt
      301 gaaacgaaga ttagtgcgcg gcttccggct tgtgcttttg cgcactctgg aagtcatacg
      361 tcaacgcatt tttctcttta tccagcgcga cggtgacctg tccgccgtca accagcgatc
      421 caaacagcaa ctcattggcc agtggttttt tcaggttatc ctggatcaca cgtgccattg
      481 gtcgtgcgcc catcgcccgg tcatagccct tttccgccag ccagtcgcgc gcttcctgac
      541 tgacttccag ggagacgcct ttctgatcca actgagcctg caactcgacg ataaacttat
      601 cgacaacctg atgaatcacc tcgccagaca gatgatcgaa ccaaataatg ttgtcgagac
      661 ggttacggaa ctcaggcgta aacactttct tgatctcacc catcgcatcg gtactgttgt
      721 cctgatgaat aagaccaata gatttacgtt cggtttctcg cacgccggcg ttggtggtca
      781 tcaccagcac cacgttgcgg aaatccgcct tgcggccgtt gttatcggtc agcgtaccgt
      841 tatccatcac ctgcagcagc aggttaaaga catccgggtg cgctttttcg atctcatcca
      901 gcaacagcac cgcatgagga tgcttaatca ccgcatccgt cagcagcccg ccctggtcga
      961 aaccgacgta tcccggaggc gcgccgatca gacggctcac cgtatgacgc tccatatatt
     1021 cggacatatc aaaacgcaac agctcaatac ccagcgcttt tgaaagctgt accgtaactt
     1081 cagttttccc tacgccagtt gggccggcga acaagaatga gccgacaggt ttatgctcat
     1141 ggcccaggcc cgcacgactc atcttaatag cttcggtcag cgcctcaatc gcgttatcct
     1201 ggccgaagac cagcattttc agacgatcgc ccaggttctt cagcgtatcg cgatcgctct
     1261 gcgagacgct cttttcagga attcgcgcaa ttcgcgccac tacggactca atatccgcca
     1321 cgttgaccgt tttcttacgt ttgctcaccg gcatcagacg cgcccgagcg cccacttcgt
     1381 caatcacgtc aatggcttta tccggcagat ggcggtcatt gatatatttt accgccagct
     1441 cgaccgccgc acgcaccgct ttcgcggtat aacgcacgtc gtggtgcgct tcgtacttag
     1501 gtttcaagcc gttgataatt tgcaccgtct cttccaccga aggctcggta atatcaattt
     1561 tctggaaacg gcgcgctaat gcgcggtctt tctcaaaaat attgctgaat tcctgatagg
     1621 tcgttgagcc gatcacccgg atcttgccgc tggaaagcag cggtttaatc agatttgccg
     1681 catccacctg tccacccgac gccgcgccag cgccgataat ggtatggatt tcatcgataa
     1741 acaggatgct gttggtatcc tgctcaagct gtttcagcaa cgccttaaac cgtttttcaa
     1801 aatcgccgcg gtatttggtg cccgccagca gcgaaccgat atccagagag taaatagtac
     1861 aatcggccat cacttccggc acatcgccct gcacgatacg ccaggccagc ccttcggcaa
     1921 tcgccgtttt gccgacgccg gattccccta ccagcaacgg gttattttta cggcgacgac
     1981 acaagacctg gatcgcgcgt tcaagttctt tttcacgacc aatcagcgga tcgatgccgc
     2041 ccacgcgagc aagttggtta agattcgtcg tgaagttttc catacgttcc tccccgccag
     2101 cttgttcgtc gccagctggc tgattgccga gatcggaaga ttggctcggt tcgtcttttc
     2161 gcgtcccgtg agaaataaag ttcacgatat ccagacggct cacttcatgc ttacgcagca
     2221 gataagccgc ctgtgattcc tgctcgctaa agatagccac cagcacattc gcgccagtca
     2281 cttcactacg cccggaagac tgaacgtgga agacggcacg ttgcaggaca cgctggaaac
     2341 ttaacgtcgg ctgcgtatca cgctcttctt cactggcagg cagtacgggt gtggtttgtt
     2401 caatgaaggc ttcgagttcc tgacggagcg ccaccagatc cacggagcat gcttccagcg
     2461 cttcgcgagc cgatgggttg ctgagcagcg ccagcaacag atgctcgacg gtcataaact
     2521 catgacggtg ctcgcgcgct ctggcgaaag ccatgtttaa actgagttcc agttcttgat
     2581 tgagcatagg cacctccccc aatttttata cctgcattca ggctttttcc agcgtacaca
     2641 gcaacggatg ctcgttctcc cttgcatact tgttcaccat cgccactttg gtttccgcca
     2701 cctcggcggt aaacacgccg cagatagctt tgccttgata gtgaactgca agcatcaatt
     2761 gcgttgcacg ttctacatca taagaaaaga atttttgtaa cacgtcaata acaaactcca
     2821 tcggagtgta gtcatcattg actaatatca ctttatacat agatggcggt tttagcgcgt
     2881 cgcgcacgct atcttccacc aactggtcaa aatccagcca atcgttcgtc ttacccattg
     2941 tcagtcgtca ttatcggtta cggttgtcgg caggaaaatc tgccgctgac cagagtctat
     3001 gcacacaatc aatctacctc aattgataga taactaacat ctatcagtac catccacgac
     3061 atctgtcaca ttcccggcaa tagcgttaac tgcttcaaat ttttgattca tttttacccg
     3121 atcccccctg cctgatgctt gacgcctcgc ctgatttctc taaattgtaa tgtcgagagt
     3181 tggtgaggtt ttgaacagcc cccactccgt caccggttca ttccatctta cttatataag
     3241 atttacgaag gatgtcgaag catggaaacg ggtactgtaa agtggttcaa caatgccaaa
     3301 gggtttggtt tcatctgccc tgaaggcggc ggcgaggata ttttcgccca ttattccacc
     3361 attcaaatgg atggttacag aacgcttaaa gccggacagt ctgtccggtt tgatgtccac
     3421 caggggccaa aaggcaatca cgccagcgtc atcgtgccca tcgaagcaga ggccgttgca
     3481 tagctcctct gtctcattgt gtacatccag aaggcaaaat gccagcccga tcggctggca
     3541 tttttattta acgccagtgc ctggtggcga cactgttgca tcttatcagg ccgacaaatg
     3601 acgtcagcaa gattactctc ttgccagcgc atccaccggg tccagtcgcg ccgcgtttct
     3661 cgccggtagc cagccaaaca atatcccggt aaacgtcgaa cataaaaacg cgctcgccag
     3721 cgctgtcagt gaaaaaccga tctcccagcc gggcaggaaa agctgtagca taaatgcgat
     3781 gaacatcgac aagctaatcc ccagcgctcc accaaccagg caaaccagca ccgcttcaat
     3841 aagaaactgc tgtagcacat cgctggcgcg cgcgcctacc gccatacgga tgccgatttc
     3901 acgcgttcgc tcggtgacgg aaaccagcat aatattcata acgccgatgc cgccgacaac
     3961 cagcgaaatg acggccacca gcgtcagaaa taactgaaga gtataggtgg ttttttcagc
     4021 cgttttcagg acgctgtcca tattccaggt gaagaagtct tttttaccgt ggcgtaaggt
     4081 gagcaggcgg gtaagctgct gttcagcctg atcgctatca acgccatctt tcacacgaac
     4141 ggtgatcgag ttaagccatg actgacccat tatgcgatct gacatcgtgc tatagggcaa
     4201 ccaaacttgc aacagattgc tattgccgta catggacggt ttctcttccg ccacgccaat
     4261 aacaataacc ggcatattac ccaccagcac cacttctcct acgacattcg ctttatttgg
     4321 aaatagctgg cgtcgcgtgt tggcatccaa caccaccacc tgcgcgcgat cctgttgctg
     4381 tacagcattg aaggtgttcc cctccctaaa ggacatgccg taaacgttaa aataatcgcc
     4441 actgacgcca ttagcattta cggcaatatc aatattgcca tagcgaagac gtaagctctt
     4501 tgaaacgctg ggcgtcgcag agttaaccca cggctgtttc tgaatagcca ccagatcgtc
     4561 atatttcagc gcctgtcgat actgcgggtt gtcgtcgcca aaatctttgc ctggatgaat
     4621 atcaatcgtg ttagtgccca tagcgcggat atccgccagt accatctgtt ttgcggcgtc
     4681 gccgaccacc acaatcgaca ccaccgacgc aataccgata ataattccca gcatggtcag
     4741 taaagtacgc attttgttag cggccatcgc taaccacgcc atcgacagcg cttcgcgaaa
     4801 gctgctggca aattgccgcc agccgggagc cgtattaact acggcagcgt caacgccctg
     4861 ttcgcgtttc ttttcctgcg cgggcggatt atggacaatc ttgccatcgt gaatttcaat
     4921 aatccgctcc gcctgggcgg caatcagcgg atcgtgcgtc acaatgatca ccgtatgtcc
     4981 gcgatcgcgc agttggcgca aaatcgccat tacctcttcg ccggaatggc tatccagcgc
     5041 gccggtcggc tcatccgcca gaatcacctg tccgccgttc atcagcgcgc gggcaatact
     5101 gacacgctgc tgctgtccgc cagaaagctg tgaaggtgga taatcgacgc gatcgcttaa
     5161 tcccagccgc aaaagcaact ctctggcgcg cgcctggcgt tttttgcgtt caatgccggc
     5221 gtagacggcg gggatttcaa cattttgcgc tgccgttaaa tgcgacaaca gatggtagcg
     5281 ctgaaagata aagccaaaat gctcacgccg cagctgcgcc agcgcgtccg ggtccagcgt
     5341 cgagacgtcc cgccccgcca cccgataagt gccgctggtc ggtttatcca ggcacccgag
     5401 gatattcatc agcgttgatt ttccagaacc ggaaacgccg acgatcgcca ccatctcccc
     5461 ggcgtggatt tgcagggaga tatctttcaa caccgccacc tgctcttctc cggaggggta
     5521 gctgcggctc acattgcaca gttcaagcaa tgccgtcatg gcgtcgctcc tggcctgctc
     5581 tcgccgatga tcacctcatc gcccgcttcc agacctttaa ccacttccac gtctgtatcg
     5641 ttacgctcgc caatgaccac ttcgcgctca cgtttttcgc cgttacgcaa cagcgccact
     5701 ttataacgat taccgcccac cggctcgcca agcgcggcga gaggaataat cagcacattt
     5761 ttgacatcca tgagttgaat ataaacctgt gcggtcatat caagacgcaa gattcttttg
     5821 ggattcggca cttcaaaccg ggcgtaataa aaaatagcgt cgttgatctt ttccggcgtc
     5881 ggcagaatat cttttaaaac gccttcatag cgcgtttgcg gatcgcctgc aatggtgaac
     5941 catgctttct gccccgcccg aagatggatc acgtccgctt ccgagacctg cgcttttacc
     6001 agcatggtgc tcatatccgc cagcgtcaga atattgggcg cctgctgagc tgcaatcacc
     6061 gtttgtcctt gcagggtagt gatttgcgtc acttcccccg ccatgggggc gacaatacgg
     6121 gtatattcca ggttggtttt cgcggtgtcc aacgaggccc gattacgttt gatctgggca
     6181 tctatggtgc caatacgcgc ctgtttaacc gccaactccg tcgccgcagt atccagatcc
     6241 tgttgcgata ccgcctgagt cttagctaac tgctgctggc gcgccagcgt aacccgcgcc
     6301 agctttaact cagcggctgc ctgctgacgc tccgcgttca gctccatcag ggtggcctcg
     6361 acctctttta tctggttctc cgcctgatct gggtcaatca cgccgagtag ctgatctttt
     6421 ttaacgttat cgccaatgga gaccagcagc gttttcaact ggccgctcac ctgcgcgccg
     6481 acatccactt tacgcaacgc gtccagtttt ccagtcgcca gtacactctg ttcaagatcg
     6541 cctggccgca cgattaatgt ctgataagtt ggcagcggcg catttatcat tcgccagcta
     6601 accatccccc ccactaaaag aattaaaata atgaccagat aacgcttttt aaatttcttt
     6661 cccttagcac gcatagaaac cctgacggca aaattttaac cagaaagtaa accgtatcta
     6721 aacaaacctg acgcaataaa gatagcgccg gctgtattga cgattggtta atgtttcctg
     6781 tggttcaatc tcgacaatct tatgtcgcgg attacgatca tgacacagct tacagataat
     6841 acctggtaca cttcagatta catctctcct ttacaattat ttattcgtct gacgcgcggg
     6901 caattacagc caggaaaatt ctggcgtaaa gccagctttc gtcgcaagtt tttaatccgc
     6961 tcattagtca tgccgcgtgc aaccagccaa ttactgacca atctcaccca atggccgaag
     7021 ttaaatacgt tacttgctcg tcagccgcgt ttgcctattc ggctacatcg tccttatatg
     7081 gctgtaaata ttaaacgcga tttcgcctta gacgctctgt gttttcatta tcaacagatg
     7141 cgccaacttt tatcgcggga acaacaagtt agctatttaa gtcagtatgg cctgaatctt
     7201 gctaaatttg aagctaaaac cggcgagttg tttcaacttg atttagtcag tctggtctca
     7261 ctggataaag aaggtgaaag cactattgtt gttcgcgacg cacagttacg tattctggca
     7321 gagatcacat ttaccctgtg tcgctttaac caacaacgca cactatttat cggcggatta
     7381 cagggcgcgg caaacgacgt ccctcacgaa attatccagc aggcgaccaa agcctgccat
     7441 ggtctttttc ccaaacgcat cgtgatggag gctctctgtc agtttgcgca agtctttcag
     7501 gcagaaaaga ttatagccgt gagtaacgat gcgcacgttt atcgtagctg gcgatacatg
     7561 gataaaaaga cgcaaatgca tgccgactat gacgcgtttt gggaatcgtt aggcggtgaa
     7621 agaattaaag ggaattacta tacgctgccg ctggcgatcg cccgaaaaag cgaagcggag
     7681 atcgccagta aaaaacgggc cgagtatcgc cgccgctatg cattactcga tagcgtcgtc
     7741 gaacaggttc cggccacatt caaacgctaa tccgcccggc cccgcgccag ccaaaccacg
     7801 cgcgagaaca tctttctgaa cagcggcggc acggcgtcaa ttccgcgccg cccggcttcc
     7861 atcgcgactt caatcgccaa atccggcttt gacgagcggt ggatagcttt agtgataatt
     7921 ttccgggtat tcatcggcac attaagcgga agttgcgcaa cccggtgaaa aacatcggca
     7981 aagccctgac gatacataaa atgttccata tccagcgtag gcagcgccgt gagatgttcg
     8041 cgttcttctt cccgatcgtt attaagcagg ctgcggaccg tcgcggcata ttttttcccc
     8101 gcttcgtcgc catccaccag gacatgccac tcgattccca tacggcgggc gaacttcacc
     8161 agcggtttca ggccagactg agcaaattca atgactttaa ttccctccgc atcaaaatga
     8221 tgtccacact gacgcgccag ctcattaata acccaggttt ccgtctcgcc ttccaccagt
     8281 agccagcaac gcgcaaacag cgacgacgcg cgattaaagc ggatatgaaa ggcgatgcgc
     8341 cgtccatctt ccgcgcttaa cccgcccgtg cccagacgcc aggcggcgac gcgggaagat
     8401 tcgcgcacca gccgtacgac atgctccacc ggcgttagcg agagcagttc gcctgagttg
     8461 gttgtcgcta tccgctgtag cggtaacaga ttgagcaatt gccaggcgac tgaaagcata
     8521 atgggatgta aacgggtttc cggatcttcc accagcagta atggtcgcgc gtctttatgt
     8581 aaccgcagcg tccctttcgc ctgtaacagc gtggagaaaa gccccagcag gatcacccga
     8641 tgcgaccggc tgcccggttt gtcgatcatc cgattaataa tatccagata gcgccagcta
     8701 cgctgctcat tttgcgaacg ccggcgcatg agtcggtgac gcgcctgtcc tgcgccctgc
     8761 tctgagaaat agtgttcaag cagttgcacc atcgcggaca gtccctgacg aatctgcccg
     8821 tcggttaaat tttgcggccg ggtcgccagc tcacgcgcca gaaaatccag ttgccgggcc
     8881 gtgacttcaa catccggcac attgggcacc gtgccgttgc gaatacgtcg cataaagcgc
     8941 gcatcgcgca aacgtagcac tggcatcaga cgaaccaggt ggcgcacctg atcgttaata
     9001 ttttccaccg gcaatggctg cccatcgcta ttgagaaaac tgcgcagcgt catcacgctg
     9061 ccatcggcgc cacattcgcc ctctagacga taaaaaatac ggtgaaaatc atcctcgcaa
     9121 ggcgaccagc atgcttccag cgcccgataa cgacgtaccc gatgccgccc tggctgcgtt
     9181 tcgcgaaaag tcagaataat atgcaggtga tgctcgcgtc cttttatgtc gccaggcgga
     9241 aaccagaaat cctcacggac aaaatggtag agatcgagtt ccggcgacaa taacagagtc
     9301 agcgcatcca gcaggctgga tttgccccag gcgttttccc caatcagcac gttgttttgc
     9361 tccagcatca acgatagtcg gttgataccg cgaaatccta ctatttcaac gcgttcgaga
     9421 atcatgcttc ctccagaaaa acgtcaccac tccattaaac tcaccgcagt ataacggcaa
     9481 atgcttccgc ctggcgtgat attcccccct ttgcctgggg caactgtctg ataaatgtac
     9541 ggctgacggt gtcgctttac tgatagtctg gaattcggta gtgtcatgta cgctattcaa
     9601 acaataaaaa agggcccggc tgttcatgtt ttcaggactt ttaatcattc tggttccact
     9661 gattgtgggc tatctcattc cactgcgaca taaagccgca ttacaactca ttaaccggct
     9721 actgagctgg atcgtgtacc ttattctctt ttttatggga ataagcctgg cgtttttgga
     9781 taacctcgcc agtaatctgg tggcgatttt tcattattcc gccgtcagta ttacgattat
     9841 tttattgtgt aatatcgccg ccttattgtg gctggaacgt atcctcccgt ggcgtcacca
     9901 tcatcagcag gaaaaactgc cttcgcgtat tgccatggcg ctggagtcgc tgcaactgtg
     9961 cggcgtagtg gtattggggt ttatcatcgg cctgagcgga ctctctgttt tacagcacgc
    10021 caccgaagcc agtgaatata cgctgatctt tttattgttc ctggtgggga ttcagctacg
    10081 aaatagcggc atgaccttaa agcaaattgt gcttaaccgc cggggaatga tggtcgcggt
    10141 cgttgtcgtg gcaagctcat tactgggcgg cgtgattaat gcgtttatcc tggacttacc
    10201 gctaaaaacc gccatggcga tggcgtcagg tttcggctgg tactctcttt ccggtatttt
    10261 gctgacggag tcgtttggac cggttatcgg cagcgcggca ttttttaacg atctggcccg
    10321 cgaacttttg gccattatgc ttattcccgg tctggttcgc cgcagccgtt caacggcgtt
    10381 gggcctgtgc ggagcgacct caatggactt tacgttgccg gtattacagc gctccggtgg
    10441 cgtagagatt gttccggcgg ctatcgtaca tggctttatc ctcagcctgc tggtacctct
    10501 cttaatggcg ttcttctcgg cctgatacct ctctggcggt aggtatctgc cgccaaaatt
    10561 gcgctaaatc aatctccttg cacattatgg cagaaatccc ttttatccct ttgttcacag
    10621 gcataatctt aaacatgtat attaaatata actttaaaag gtgtgaccat gttttgtgtg
    10681 caatgtgaac aaaccatccg tacaccagcc ggaaacggct gctcctacgc gcagggaatg
    10741 tgcggtaaaa cggctgaaac gtccgatctg caggatctgc tgattgcggc tttgcaaggt
    10801 ttgtctgcct gggcggtgaa ggcccgtgaa tatggcatca ttaatcacga cgttgataac
    10861 tttgcgccgc gcgcgttttt ctccacgctg accaacgtta acttcgactc tccgcgtatc
    10921 gtcggctacg cccgtgacgc tatagccatg cgtgaagcgt tgaaagccca gtgcctgagc
    10981 gtggatgcta atgcgcattg cgacaatccg atggccgatc tgcaactggt tagcgacgat
    11041 ctgggcgaac tgcaacgtca ggcagcggaa tttaccccga ataaagataa agccgccatt
    11101 ggcgagaaca tcctcggcct gcgtctgctg tgcctgtacg gtctgaaagg cgcggcggcg
    11161 tacatggaac acgcgcacgt tctcggtcaa tacgacaacg acatttatgc gcagtaccac
    11221 aaaatcatgg cctggctcgg cacctggcct gctgatatga acgcgctgct ggagtgcgca
    11281 atggaaatcg gccagatgaa ctttaaagtg atgagcattc tggatgccgg tgaaaccacc
    11341 aaatacggtc acccaacgcc gactcaggtc aacgtcaaag cgactgaagg caagtgcatt
    11401 ctgatctccg gtcacgatct gaaagatctc tacaacctgc tggagcagac cgaaggcacc
    11461 ggcgttaacg tctacactca cggcgaaatg ctacccgcac acggctaccc ggaactgcgt
    11521 aaattcaagc atctggtcgg taactacggc agcggctggc agaatcagca ggtcgaattc
    11581 gcccgcttcc ctggcccaat cgtgatgacc tctaactgca ttatcgaccc gaccgtgggc
    11641 agctatgacg accgtatctg gacccgtagc atcgtcggct ggccgggcgt tagccatctt
    11701 gaaggtgatg acttcgggcc ggtcattgcc caggcgcagc agatggcggg cttcccgtat
    11761 agcgaaattc cgcatctcat caccgtcggt tttggtcgtc agaccctgct cggcgctgcc
    11821 gatacgctca tcgatctggt cagtcgtgaa aaactgcgtc acatcttcct ggtcggcggc
    11881 tgtgacggcg cgcgcggcga gcgtaactac tttaccgatt tcgtcaccag cgtgccggat
    11941 gactgcctga ttctgactct ggcgtgcggt aaataccgtt tcaacaaact ggagttcggc
    12001 gacatcgaag ggctgccgcg tctggtcgat gccggtcagt gtaacgatgc ttactccgcg
    12061 attatcctgg cggtgacgct ggcggaaaaa ctgggctgcg gcgtcaacga tctgccgcta
    12121 tcgctggtgc tctcctggtt tgagcagaaa gcgatcgtta ttctgctgac gctgctgtca
    12181 ttaggcgtga aaaatattgt caccgggccg accgcaccag gcttcttcac gccggatttg
    12241 ctggctatcc tcaacgagaa gttcggtctg cgctccgtga ccactgttga agaagacatg
    12301 aagcaattgc tgagcgcgta aggaggccaa tgatgacgat gccaacctca caatgtccct
    12361 ggcgaatgca ggtgcatcac atccgtcagg agacgccgga tgtatggaca attgcgctat
    12421 tatgccatga ctactaccct taccgcgccg ggcagtatgc gctggtgagc gtgcgcaatt
    12481 cagcggaaac gctgcgcgcc tacacccttt cgtctacgcc gggcgtcagt gaatatatca
    12541 cgctgaccgt tcgtcggatt gaagatggca cgggttcaca gtggttgacc catgacatca
    12601 agcgcggcga ttacatctgg ctgtctgatg caatgggcga ttttacctgt gacgataaaa
    12661 cagaagataa gtttctgctg ctcgccgccg gttgtggcgt aacgccaatc atgtcgatgc
    12721 gtcgctggct ggcgaaatac cgcccgcagg ccgacgtgca ggtcatcttt aacgtccgtt
    12781 cgccggatga tgtgattttt gccgacgagt ggcgacagta tccggtcacg ctagtggcgg
    12841 aaaatcatgc cacggaaggt tttatcgcgg gccgtctgac cacggaattg ttacagcgcg
    12901 taccggattt ggcatcgcgc actatcatga cctgcggccc ggcgccctat atggatttcg
    12961 ttgaacaggg agtgaaagcg cttggcgtaa cgcacttctt taaagagaag ttcttcacgc
    13021 cggtggcgga aacggcaacc agcggcctga aattcaccaa actacagcca gcgcaggaat
    13081 tttatgcccc aatcggtacg acgctgctgg aggcgctgga gagtaataaa gtaccggttg
    13141 ccgctgcctg tcgggcaggt gtttgcggct gctgtaaaac caaagtcgtt tccggcgact
    13201 atacggtgag cagcaccatg acgctgagcg aggcggagat tgccgaaggt tacgtactgg
    13261 cctgctcctg ccatccgcag ggcgatcttg ttctcgcata atcggtaaac gttccatcgt
    13321 aggcccggta agcgtcagcg ccaccgggcg atttaccact cgcttcatcc tttcgcccct
    13381 ctctccgcca aagaaaaacg tcatcgtcat cttcaactaa acttgtaacc gttatcacat
    13441 ttaaggagat ggagaaccat gaaacaaacc gttgctgctt ttatcgccaa aacgctggaa
    13501 caggctggcg taaaacaaat ctggggcgtc actggcgact ccctgaacgg cctgagcgat
    13561 agtcttaatc gtatgggaac cattgaatgg atgccaaccc gccacgaaga ggtcgccgct
    13621 ttcgccgccg gcgcacaagc gcagcttacc ggcgagctgg cagtgtgcgc cggttcatgt
    13681 ggaccgggca acctgcacct gatcaatggc ctgtttgatt gccaccgtaa ccacgtccct
    13741 gttctggcga tcgccgccca tattccgtcc agtgaaatcg gcagcggtta tttccaggag
    13801 acccacccgc aggagttgtt ccgtgaatgc agccactatt gcgagttggt ttccagcccg
    13861 gagcagatcc cgcaggtact cgccatcgcc atgcgcaaag cggtgctaaa tcgcggcgtc
    13921 tccgtggtcg tacttccggg tgacgtggcg ctgaaacccg cgcctgaaaa cgccgtcacc
    13981 cattggtacc atgccccgca ccccgtcgtt acgccggcgg aggaagagct gaaaaaactg
    14041 gcgcaactgc tgcgctactc cagcaatatc gcattgatgt gcggtagcgg ctgcgcgggc
    14101 gcgcatgagg agttggtcgc gttggcggca aaactaaaag cgccaatcgt tcatgccctg
    14161 cgcggcaaag agcacgttga gtacgataac ccttatgatg tgggaatgac cggcctgatt
    14221 ggcttctctt ctggcttcca caccatgatg aacgccgata cgctgatcct gctcggcacc
    14281 cagttcccct atcgcgcctt ttatccgagc gatgccaaaa tcattcagat tgacatcaac
    14341 ccgggcagta ttggcgcgca cagcaaagtc gacatggcgc tggtgggcga tattaaagcc
    14401 acgcttcgcg ccctgctgcc gctggtggaa gaaaaaagca atcgtaaatt cctcgataaa
    14461 gctctggaac actatcggga cgcccgtaaa gggcttgatg acttagccaa actcagcgat
    14521 aaagccatcc acccacaata tctggcgcaa caaattagtc atttcgccgc tgacgacgct
    14581 atttttacct gcgatgtcgg cacgccgacc gtctgggcgg cccgctatct aaaaatgaac
    14641 ggcaagcgcc gcctgctggg ctcgtttaac cacgggtcaa tggccaacgc catgccgcag
    14701 gcgctcggcg ctcaggccac cgcgccgggt cgtcaggtta tcgcgatgtg cggtgatggc
    14761 ggcttcagta tgctgatggg cgattttctc tcggtggtac agatgaagct gccgataaaa
    14821 atcgtcgtct ttaataacag cgtgctgggc tttgtggcga tggaaatgaa agctggcggt
    14881 taccttaccg acggtaccga actgcacgac accaatttcg cgcgtatcgc cgaagcctgc
    14941 ggcattaccg gtattcgcgt ggaaaaagcc gcagacgtgg acggagcgct acagcgcgcg
    15001 ttttccatcg atggcccggt actggttgac gtggtcgtgg caaaagaaga gctggcgatc
    15061 ccgccgcaga tcaaactgga acaagcgaaa ggctttagcc tgtacatgct gcgcgccatt
    15121 attagcggcc gcggcgatga agtgatcgaa ctggcgaaaa caaactggct aaggtaaaac
    15181 agtgcacatc accttttaaa atccagggat gtgccatgat tgatttacgc agtgataccg
    15241 ttacccgacc gggccgcgcc atgctcgagg cgatgatgac cgccccggtc ggggacgacg
    15301 tatacggcga tgcccctacc gttaacgccc ttcagcgcta cgccgccgac ctttccggta
    15361 aagaagcggc gcttttttta cccaccggca cccaggccaa tctggtcgcg ctgcttagcc
    15421 attgtgaacg cggcgaagag tatatcgtcg gtcagggcgc acataattat ctctatgaag
    15481 ctggcggcgc tgcggtgctc ggcagcattc agccgcagcc tattgatgcc gccgcggacg
    15541 gtacgctgcc gctggagaac gtagcggcga agattaaagc ggatgacatc cacttcgcgc
    15601 gcacgcgctt gctcagtctg gaaaatacgc ataacgggaa agtgctgccg cgcgcgtatc
    15661 tgaaagacgc ctggacgttt acccgcgaac gtgggctggc gctgcacgtt gacggcgccc
    15721 gaatttttaa cgcggtggtt gcctacggct gtgagttaaa agagattacg cagtattgcg
    15781 actcttttac catctgcctg tcaaaaggtc tcgggacgcc ggtcggttcg ctgctggtcg
    15841 gcaaccgcga ttacattaaa cgcgcgacgc gctggcgtaa aatggtcggc ggcggaatgc
    15901 gtcaggccgg gattctggca gcggccggac tgtatgcgct gaagcataac gtggcgcgtc
    15961 tgcaagagga tcatgacaac gccgcctggc tggcgcagca gcttcgcgaa gcgggcgcgg
    16021 atgtcatgcg ccacgaaacg aatatgctgt ttgttcgcgt tggcgaagca caggccgccg
    16081 cgcttggcgg ctatttgcgg gaacggaata tcctgattaa cgccgcgccg attgtgcgtc
    16141 tggtgacgca tctggatgtc tctcgcgaac agcttgccga cgtcgtcgcc cactggcgcg
    16201 cctttttagc ccgctaagga gagcaacgtg gcgcaacgca ttctggtcct cggcgccagc
    16261 ggctatatcg gtcagcacct ggtctttgcg ctaagtcagc aaggacatca ggtgcgggcg
    16321 gcggcgcggc gcgtggaacg tctggaaaaa catcgcctcg ccaacgtcag ttgtcataag
    16381 gtcgatctgc actggccgga aaatttaccc gcgctgcttc gcgacattga taccgtttac
    16441 tatctggtac acggcatggg cgaaggcggc gactttatcg cccatgagcg tcaggcggcg
    16501 ctcaacgtgc gcgacgcgct gcgccagacg ccggttaaac aacttatttt cctcagttca
    16561 ttgcaggcgc cggcgcatga gcaatccgat cacctgcgcg cccgccagct tacggctgac
    16621 acgctgcgcg acgcaggcgt accggtgacg gaattacgcg ccgggatcat cgtcggcgca
    16681 ggctccgccg cctttgaggt catgcgcgac atggtttaca acctgccaat actcacgccg
    16741 ccgcgctggg tgcgttcgcg caccacgccc atcgccctgg aaaatttact ctactacctg
    16801 gtcggcttac tggagcaccc tgcgcacgag catcgtattc tggaagccgc cgggccgcag
    16861 gtattaagtt atcagcagca gtttgaacgt tttatggccg tcagcggtaa acggcgtccg
    16921 ctgatcccgg tgccttttcc gacccgctgg atttcggtct ggtttttaaa cgtcattacc
    16981 tccgtgccgc caactaccgc aaaagcgtta atccagggat taaggcacga tttgctggcc
    17041 gatgacgccg cgttaaaaaa gttgatcccc caaacgctta tcacctttga tgacgccgtt
    17101 cgccgcacgc tgaaagaaga agaaaaactg gtgaactcca gcgactgggg ctacgacgcg
    17161 ctggccttcg cccgctggcg tcccgaatac ggctattttc caaagcaggc gggctttacc
    17221 gcgcagaccc cggccagcct atcggcgcta tggcaggtcg taaatcggct gggtggcaaa
    17281 gagggctatt ttttcggcaa tattttgtgg cagacgcgcg ccgcgatgga ccgtctggtg
    17341 gggcataaac tggcgaaagg ccgcccgtcg cataccttgc tcaagcctgg cgatacggta
    17401 gatagctgga aagtgatcat tgtcgaacca gaaaaacagc tcacgctctt gtttggcatg
    17461 aaagcgccgg gtctggggcg gcttagcttc acgctgcacg ataaaggccg ctaccgcgaa
    17521 attgacgtgc gcgcctggtg gcatccacac ggaatgccgg gcctgattta ctggctactg
    17581 atgatcccgg cgcacctgtt tattttccgg ggaatggcaa ggcgtattgc ccgacttgca
    17641 gaacaaatca cagaaaaatg agaaaaagtt gctgtattct ttcgtgtttc ccattgcata
    17701 ccgacgtaat tcacggaaga atgcgcacga cggtttatta aacacagtgg attgatatga
    17761 aggtactggt taccggcgcc accagcggct taggtcgaaa cgcggttgaa tttttgcgca
    17821 ataaaggcat cagcgtcaga gcgacgggtc gcaatgaagc gatgggcaag ctgcttgaaa
    17881 aaatgggcgc ggaattcgtc catgcggatt taaccgaact ggtctcctcg caggctaaag
    17941 tgatgcttgc cgggatcgac acgttgtggc actgctccag ctttacctcg ccctggggaa
    18001 cccaacaggc tttcgatctg gcgaatgttc gcgccacccg ccgtctggga gaatgggcgg
    18061 tcgcctgggg cgtgcgcaat tttattcata tctcctctcc ctcgctctat tttgattacc
    18121 accatcaccg tgatatcaaa gaagatttcc gcccgcatcg gtttgccaat gagttcgccc
    18181 gcagtaaagc cgccggcgaa gaggtgatta atctgttggc gcaggccaat ccgcaaacac
    18241 gttttacggt attgcgtcca caaagcctgt ttggcccgca cgataaagta tttatcccac
    18301 gtctggcgca tatgatgcac cattacggta gcgtcttatt accgcacggg ggcagcgcgc
    18361 tggtcgatat gacctactat gaaaatgcga tccacgccat gtggctggcc agccagccgg
    18421 gctgcgatca tctgccttct ggccgcgctt ataacatcac taacggcgaa aaccgcacct
    18481 tacgcagcat cgtacaaaag ttaattgatg aattgactat cgactgccgc attcgctctg
    18541 tgccttaccc gatgctggat atgatcgccc gcagtatgga gcgcttcggc aaaaaatccg
    18601 ccaaagagcc cccgctaacg cattacggcg tgtcaaaact gaattttgat tttacgctcg
    18661 atacgactcg cgcgcaggac gagctgggct accagcccat cgtcacgctg gacgaaggta
    18721 ttgagcgcac cgccgcctgg ctgcgcgatc acggaaattt accgcgttaa tcctggccgt
    18781 acttctccag taatgcttcg gcaatcgcct gcgtttcggc atctgcgata ccgttccatt
    18841 gcgccggacg gaagtgcatc tggaacgcca taatcacccg ctgttgctcg cgcgccgtca
    18901 tatcggcttt gacttcatag ccatagcgcg agagtaacgc aagcaccgtt gcggtatcga
    18961 ctggcgtata cggcgcgcgt ccagccagat aaaacgccac acgctgggcg tcaggccagg
    19021 cgccaatccc ctgtgccgcc agctcgcgcc acgggaagcg cgggccggga tcgtctttac
    19081 gctgcggcgc gatatccgca tgggccacca cattctgcgg tttgatgtca tagcgcgcga
    19141 taatgtcctt cgctaacggg atcaatgcct gaatttgcgc ggattcaaac ggcgcgaaag
    19201 atttcacccc gccggacatt cgccagccgc gattttccag ctcaatgcca atagacgtat
    19261 cattgagacg cgtggcgcct cgccagaaac tgacgcccgc atgccaagcc tgatcctgtt
    19321 ccggcaccag ttgccagatg cgcggtttac cgccatataa tggcggggtt gcgggaatca
    19381 ggtaatgcga actgacgttg cgacccgtta acgtcgccag cgaaacgtca aagttttccg
    19441 ccgtatagtg aatcaccagg actttaatgc gcggataggc cgcctgcgcc cgatgtcggg
    19501 tatcaagctg atatccctct ttatcgataa ttcctttttc gctcgcgcag cctgttaaca
    19561 gcaacgcgag accaaccagc cacagtagcg ctttcatcgg cgcgttttca ccgccgttcc
    19621 gctgacgctg accatcagca tactgccatc cttgccgaca gtttcgtaat caatatcgat
    19681 gcctaccacc gcatcggcgc ccaacgcttt agcctgctcg ccaagttcct gaaaagcgat
    19741 ttcacgcgct ttacgcagct ctttctcata cgcgccggaa cgtccgccga cgatatcccg
    19801 aatgccggcg aaaaaatcgc ggaaaatatt ggcgcctaaa atggcttcgc ccgttaccac
    19861 accgcaatac tccacgatgc tttgtccttc cagcgttggg gttgttgaaa actgcatagt
    19921 gaatctcccg ggttagctaa gcacacgatc tcaaacgcat tatcaagctg atacgctatc
    19981 attgaaagga tataattgat tatcgtagat cggtttttgc tcgatcgcct ataaggaaat
    20041 catcatgcgc tattctaaac tctctttgct catcccgtgc gcgcttctgc ttagcgcctg
    20101 tacgaccgtc actcccgcct acaaagataa tggcccgcgt atcggcgcgt gtgtggaagg
    20161 cggcccggac agcgtggctc aacaatttta cgactaccgt attcaacacc acagcaatga
    20221 tatcgccgcg cttcgcccct acttgagtga taacctggcg aaattgttga ccgacgccag
    20281 ccgcgatacg gaacaccgcc agttgatgag cggcgatatg ttctccagcc gcgctacgct
    20341 gccggatagc gccaacgtcg ccagcgcatc aaccattccg aaccgagatg cgcgcaatat
    20401 tcctctgcgg gtggcgttaa aacagggcga tcaaagctgg caggatgaag tgcttatgat
    20461 tcacgaaggc tcatgctggg tgattgacga cgttcgctat ctgggcggag atgtccatgc
    20521 ccctgccggt acgctgcgcc agtcgataga aaaccgttaa cagtcagtat tccccgcttt
    20581 tgcacccata accccgtaaa ttgtctggca ttctgcacgg gatgccgaca attcttctta
    20641 cctactattc ctcctgctat tttgtgctat gtttagggaa gaatgtggga tatatttaac
    20701 ttttaacgca taaatattgc ataactattc tgcgaaaggt actatctgcg gcttcaatag
    20761 ctatcagact gcctgtatac gagtgtcaat gagtattcaa ttaaacggca ttaattgctt
    20821 ttacggcgcg catcaggcgc tgttcgatat cacgctggat tgccccgaag gcgaaacgct
    20881 ggtgttgctt ggcccaagcg gggcgggtaa aagttcgctg ctgcgtgtac tcaatctgct
    20941 tgagatgccg cgctccggca ctctgactat cgccgggaac cattttgact ttacgaaaac
    21001 gccgtccgat aaggcgattc gtgagctacg tcaaaatgtc ggaatggtct ttcaacaata
    21061 taatctttgg ccgcatctca ccgttgtgca gaatctgatt gaagcgccct gccgcgtact
    21121 gggtctgaca aaagatcagg cgctggcgcg cgcagaaaag ctgctggagc gtttacgtct
    21181 gaagccctat agcgatcgtt atccgttgca cctttccggc ggtcagcagc agcgcgtcgc
    21241 gattgcccgc gcgctgatga tggagccgca ggtgctgctg tttgatgaac cgaccgccgc
    21301 gctggacccg gaaattaccg ctcaaatcgt cagcattatt catgagctgg cggaaacgaa
    21361 cattactcag gtgatcgtta cgcatgaagt cgaagtggcg cgtaagaccg ccagtcgtgt
    21421 gatttatatg gaaaatggtc acatcgtcga gcacggtgat gcgggttgct ttgctcaccc
    21481 tcagaccgaa gcgttcaaaa actatctctc tcactaagat tcgggacaat gacaatgaaa
    21541 aaagttctga ttgccgcgct aattgcaggc tttagccttt ccgctacagc agcccagacc
    21601 attcgttttg cgaccgaagc gtcctatccg ccgttcgaat cgatggatgc taataacaag
    21661 attgtcggct ttgacgtcga cctggccaac gcgctatgta aagagatcga cgcctcctgt
    21721 acctttacca atcaggcgtt cgacagcctg atccccagcc tgaaattccg ccgcttcgac
    21781 gctgtaatgg cgggaatgga tatcacgccg gaacgtgaaa agcaggtgct gtttaccacg
    21841 ccatattacg acaactccgc gctgttcgtg ggtcagcagg gcaaatacac cagcgtcgat
    21901 caactgaaag gtaagaaagt cggcgtacag aacggtacga cgcaccagaa attcatcatg
    21961 gataagcatc cggaaatcac caccgtaccg tatgacagct atcagaacgc gaagctggat
    22021 ctacaaaatg gccgtatcga cgctgttttc ggcgacacgg cggtcgtgac cgaatggctg
    22081 aaagccaatc ctaagctggc gccggtcggc gataaagtca ccgataaaga ttatttcggc
    22141 accggcctgg gtatcgcggt acgtcagggc aacaccgagc tgcagcagaa attcaatact
    22201 gcgctggaaa aagtgaagaa agatgggact tacgagacca tctataacaa atggttccag
    22261 aagtaatctt tgatgaacga attttttcct ttagcaagcg ccgccgggat gaccgtcggc
    22321 cttgccgtct gtgcgctgat cattggcctc gcgttagcca tgttctttgc cgtctgggag
    22381 tccgtaaaat ggcgcccgat tgcctggata ggctccgcgc tggtcactat tttgcgcggc
    22441 ctgccggaaa ttctggtggt gctgtttatc tatttcggct cctcgcaact cctgcttacg
    22501 ctgtctgacg ggtttaccct ccatctcggt tttacgcaga tcccggtgca aatggagatt
    22561 gagaactttg acgtcagtcc gttcctgtgc ggcgtgattg cgttgtccct gctgtatgcg
    22621 gcctatgcgt cgcagacgct acgcggcgcg ctgaaagccg ttccgtctgg tcagtgggag
    22681 tcgggtcagg cactgggatt atcaaagacg gcgatttttt tccgtctggt gatgccgcag
    22741 atgtggcgtc acgccctgcc agggctgggt aatcagtggc tggtgttgct aaaagatacg
    22801 gctctggtca gccttatcag cgttaacgat ctgatgttgc agaccaaaag tattgccaca
    22861 cgcacccagg aaccgtttaa ctggtacatt attgcggcgg ctatttacct ggtcattacg
    22921 ctgatcagtc agtacattct caaacgcata gacctgcgcg caacacgttt tgagcggagg
    22981 ccggactaat gcttgagtac ttacctgaac tgctaaaagg gctacacacc agcctgacgc
    23041 tgaccgtggc ttctattgcc gtcgctttgg tgctggcgtt agtttttacc atcatcctga
    23101 cgctaaaaac gccgttcgtg gtgtggctgg tgcgcggcta tatcacgttg tttaccggta
    23161 cgccgttgtt ggtgcaaatt ttcctgatct actacggacc cggtcaattc ccgacactgc
    23221 aagagtatcc gctactctgg catctactgt ctgaaccgtg gctgtgcgca ctgatcgcgt
    23281 tgtcgctaaa cagcgccgct tacaccacgc agctatttta tggcgcgatt cgcgcgattc
    23341 cggaaggtca gtggcagtcc tgcggcgcgc tggggatgag taagaaagat acgctggcga
    23401 ttttgttgcc ctatgcgttt aaacgcgccc tctcctccta ttctaatgag gtggtactgg
    23461 tcttcaaaag tacctcgctg gcctatacca tcaccttgat ggaggtcatg gggtacagtc
    23521 agttgctcta tggtcgtacc tacgatgtgg tggtatttgg cgcggcaggc gtaatttacc
    23581 tggtcgtcaa cggtctattg acgctgatga tgcgtttgat tgagcgtaaa gccctggcgt
    23641 ttgagcggcg caattaacca ggcaggataa ggcattctcg ccgccgttcg acaatggtca
    23701 gatggcgctg cgcttatcaa gcctacgatg cataatattg aataaacccg acggacaagt
    23761 ggttaacttg tccgtctttt tttatccatt ttaaaatatt taatcatttt tattgcatac
    23821 aaattcaatt gatggcattg taaatctatg ccgcagacac ggcgcataat cataagatta
    23881 cgggagtgac atcatgaaaa agttagttct ggctgcatta ctcgcctctt tcgccactgg
    23941 cagcatcgcc gctgaaaaaa tcaatttcgg ggtttccgcc acctatcccc cgtttgaatc
    24001 cctggatgcg agtaataaaa ttgtgggctt cgatatcgat ctggcaaccg cattatgcaa
    24061 gcaaatgcag gcagaatgta cttttaccaa tcatgctttc gatagtctta tcccggcgct
    24121 gaaattcaga aaatatgatg ccgtcatttc cggaatggac attaccccgg agcgcagtaa
    24181 gcaggtcgcc tttagcaatc cctattatgc gaactccgcg ctggtgattg ccaaaaaaga
    24241 cacctataaa acctttaccg atctaaaagg taagcgtatc ggtatggaaa atggcaccac
    24301 gcatcaaaaa tatctccagg ataaacatcc ggaggtcaaa accgtggcct acgacagcta
    24361 ccagaatgcg attatcgacc tgaaaaatgg ccgtattgac ggcgtctttg gcgataccgc
    24421 agtggtcaat gagtggctga aaacgaatcc gcaactgggt ccggcaacag agaaagtgac
    24481 cgatccgcaa tacttcggta ccggacttgg catcgcggtg cgcccggaca ataaggcgtt
    24541 gctggaaaaa ctgaataatg cgctggccgc cattaaagcg gacggcactt atcagaaaat
    24601 cagcgatcag tggttcccgc agtaaaacgt atgtgattag cccaccgtgt tgcgaaatgg
    24661 cagtataaat accttattca gcccacgggc cgctatcgga aactatcctg gcctgataag
    24721 cgcagcgcca ttgagcattc tacagtttgt catcagtctc aaaggcctgc atcaacaggc
    24781 gattcggact catacttgcc gggtgacgct aacgcgtacc cggcttacaa cattgttatg
    24841 tttttagaca acatccagac ccagacggcg atactgctcc gccggagcgt cattttcttt
    24901 catcaaacgg ataagtaagt tgatcatcct tgcttcgatg gcctcatcat gaataggatg
    24961 ttgctgctgc ggatcgtctc tgagatcaaa caagagatga ccaaagctat tcacaccttt
    25021 atatttttcc ctggccggaa tacgtaatac ctgaagccct ttagtgaatt taaacggagg
    25081 tgccagagat aattttccca gttcatccac gtcataacgc gcattcatct tgatcggcat
    25141 taacgtgtag ttcgcaatgt catgctcacg ccccggctgc gcggcccgca tataaacata
    25201 gcgtccgtcg gtaacattaa catgtccgct aaacacgcca aacagcgcgc cttccctgac
    25261 gggttcatca ctggcaatga ctttcgccag aggttggccc tgcatatctg cgggaatagg
    25321 ttgctgaaaa taatccagta gcgttggcgc ccagtcaatc atctgcacca gcgactgccg
    25381 tcgcgctccg cataccgcgc tgcgcgggtc ccagataaac agcgggttat tcgccacctc
    25441 gttataatag ggcatttgat ttttagccca ccaaccgtgc tcccccagca agaagccgtg
    25501 atcggtaccg acaatcagca tcgtatcgcg ccagagatcg tgttcatcca tcagatcaag
    25561 gatacgtccc agattgcggt cgcacatgga aaccagggcc cgataacgac agcgaatatg
    25621 cgctatcgcc tcctcacttt cactgacttt gccgcgcggc cagtcataat gcgagccttg
    25681 ccactcatcg tcatagagcg ataaatattc ctcggtggta taaaacggct catgcggatc
    25741 gaacgtctca acctgcaata accagttatc ttcggcatga tttttatgga taaaatcgca
    25801 cccggcgtca aaaactttcg tctggggaaa atcggcttcc tgctggatgt attcgcggtt
    25861 cgcccagtca tgacgccata gcccggaaac gccgcctccg gtttgttttt gtggaacgcg
    25921 cagtacttcc ggaatgggcg gctcgccaac acttgccttc cagtgatcgc cctcctgacc
    25981 gcgtactacg tcccaggagc tatagcggtt atggtagtta ccgccgccgt cttcccagta
    26041 atgcagatga tcgctgataa gatgggtgta gatccccgct tttttcaata attccggcat
    26101 ggaatcatca aagggttcca gcggccccca ctcacgatgc aggaaattat agcgcccggt
    26161 gtgcagttcc cgacgggctg gcatacaggg catactgccg acataactat tgtcaaaggt
    26221 ggcggcatgt gccgccaggc gttgaaagtt aggcgctttc gttagcaaat caccataggg
    26281 cggcaaatag tttttattca gactgtcaaa cagcagaata atcgctttca tgactcaccc
    26341 tcatttgttg agcaggtgcg gaaaattttt ctctaccaca tcgtaaatct gtttacctat
    26401 tgattcgcta tccatgatat tttcaatggg aatgagatat tgtccgtgtt taggatcgag
    26461 gctaacaaca tcaagcaatt ttttcgaaat cgcataaata tctgcccagt cggtaaatcc
    26521 accgacctct cccgctgccg tatgctccat atcaaaagag aagtcatatt ttgctaacgc
    26581 ttttttaaca acagtctgta
//
LOCUS       DAJVBX010000037        26361 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.037, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000037 DAJVBX010000000
VERSION     DAJVBX010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 26361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26361
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.037"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            170..724
                     /locus_tag="OPV72_001376"
     CDS             170..724
                     /locus_tag="OPV72_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HCR9913729.1"
                     /translation="MSDTLRPYKDLFPEIGQRVMIDTSSVVIGDVRLADDVGIWPLVV
                     IRGDVNYVAIGARTNIQDGSVLHVTHKSPSNPHGNPLIIGEDVTVGHKVMLHGCTIGN
                     RVLVGMGSIVLDGAIIEDDVMIGAGSLVPQHKRLESGYLYLGSPVKQIRPLSDAERSG
                     LQYSANNYVKWKDDYLSQDNHIQP"
     gene            complement(700..957)
                     /locus_tag="OPV72_001377"
     CDS             complement(700..957)
                     /locus_tag="OPV72_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1488 domain-containing protein"
                     /protein_id="HCR9913730.1"
                     /translation="MNQAIQFPDREEWDTAASAIIFPALVNGMQITCAIKKDVLAYRF
                     GGETAEQWLAIFREYRWDLEEEAEALILAQQEDDHGWIWLS"
     gene            complement(954..1772)
                     /gene="aroE"
                     /locus_tag="OPV72_001378"
     CDS             complement(954..1772)
                     /gene="aroE"
                     /locus_tag="OPV72_001378"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HCR9913731.1"
                     /translation="MEAYAVFGNPIAHSKSPFIHQQFAQQLDIVHPYGRVLAPINNFI
                     NTLDAFFAAGGKGANITVPFKEEAFARSDELTERASLAGAVNTLKRLEDGRLLGDNTD
                     GIGLLSDLERLNFIRPGLRILLIGAGGASRGVLLPLLSLDCAVTITNRTASRAEALAK
                     IFAHTGSVHAMDMDKLDGCEFDLIINATSSGIRGEIPAIPASLIHPSLCCYDMFYQKG
                     NTPFLSWCVQQGAKRYADGLGMLVGQAAHAVLLWHGVLPQVEPVIKLLQQELLA"
     gene            complement(1777..2349)
                     /gene="tsaC"
                     /locus_tag="OPV72_001379"
     CDS             complement(1777..2349)
                     /gene="tsaC"
                     /locus_tag="OPV72_001379"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase type 1
                     TsaC"
                     /protein_id="HCR9913732.1"
                     /translation="MNNNLPTGSSAAVVDLLNKENVIAYPTEAVFGVGCDPDSETAVT
                     RLLALKQRPVDKGLILIAASFEQLKPYIDDSILTAAQRKAVFDCWPGPVTFVFPAPAT
                     TPRWLTGRFDSLAVRVTNHPLVVALCNAYGKPLVSTSANLSGLPPCRTVEEVRAQFGD
                     DFPVVEGATGGRLNPSEIRDALTGELFRQG"
     gene            complement(2354..2896)
                     /locus_tag="OPV72_001380"
     CDS             complement(2354..2896)
                     /locus_tag="OPV72_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase"
                     /protein_id="HCR9913733.1"
                     /translation="MAKSALFSVRKNEPCPQCGAELVIRSGKHGPFLGCSRYPECDYV
                     RPLKSQADGHIVKILEGQLCPECGAVLVLRQGRFGMFIGCSQYPQCEHTVVIDKPDET
                     AIACPACQQGHLVQRRSRYGKIFHSCDRYPECQFVINFTPVAGECPECHYSLLIEKKT
                     AQGVKRFCASKQCGKPVPVE"
     gene            complement(2923..3396)
                     /locus_tag="OPV72_001381"
     CDS             complement(2923..3396)
                     /locus_tag="OPV72_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005134083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF494 domain-containing protein"
                     /protein_id="HCR9913734.1"
                     /translation="MFDVLMYLFETYIHNEAELRVDQDRLERDLTDAGFDREDIYNAL
                     LWLEKLADYQDGLAEPMQLASDPLSMRIYTVEECERLDASCRGFLLFLEQIQVLNLET
                     REMVIERVLALDTAEFDLEDLKWVILMVLFNIPGCENAYQQMEELLFEVNEGMLH"
     gene            complement(3368..4492)
                     /gene="dprA"
                     /locus_tag="OPV72_001382"
     CDS             complement(3368..4492)
                     /gene="dprA"
                     /locus_tag="OPV72_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HCR9913735.1"
                     /translation="MARTEIWLRLMYVGDLYGEAMLNMANSLIRQPQINRTHLQEAGL
                     TARQAERFLQLPAGVLDETLRWLELPQHHFLCADSEIYPPQLRAIDDYPGAIFIDGDP
                     ACLHTCQLAVVGSRSHSWYGERWGRLLCESLAKSGLTITSGLARGIDGVAHNAAMSMG
                     GKSVAVLGNGLAKIYPRRHAMLAENLIATGGAVVSEFPLSTPPLSQNFPRRNRIISGL
                     SKGVLVIEAALRSGSLVTARCALEQGRDVFALPGPIGSPGSEGTHWLIKQGATLVTTP
                     EDILENLQYGLHWLPTTAENSLYSLNQDEAALPFPELLANVGDEVTPVDVVAERAGQP
                     VPAVVAQLLELELAGWIAAVPGGYVRLRRASHVRRTNVFV"
     gene            4624..5133
                     /gene="def"
                     /locus_tag="OPV72_001383"
     CDS             4624..5133
                     /gene="def"
                     /locus_tag="OPV72_001383"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HCR9913736.1"
                     /translation="MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEG
                     IGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVP
                     RAEKVKIRALDRNGNPFELEADGLLAICIQHEMDHLVGKLFIDYLSPLKQQRIRQKVE
                     KLDRLNARA"
     gene            5149..6096
                     /gene="fmt"
                     /locus_tag="OPV72_001384"
     CDS             5149..6096
                     /gene="fmt"
                     /locus_tag="OPV72_001384"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HCR9913737.1"
                     /translation="MSDSLRIIFAGTPDFAARHLDALLTSGHNIVGVFTQPDRPAGRG
                     KKLMPSPVKVLAEEKGLPVFQPVSLRPQENQHLVADLHADVMVVVAYGLILPKAVLDM
                     PRLGCINVHGSLLPRWRGAAPIQRSLWAGDAETGVTIMQMDVGLDTGDMLYKLACPIT
                     AEDTSGSLYNKLAELGPQGLITTLKQLADGTATPEAQNEALVTHAEKLSKEEARIDWS
                     LSAAQLERCIRAFNPWPMSWLEIDGQPVKVWQASVIEDATQSLPGTILAATKQGIQVA
                     TGKGILNLLSLQPAGKKAMSAQDLLNSRREWFIPGNRLA"
     gene            6148..7437
                     /gene="rsmB"
                     /locus_tag="OPV72_001385"
     CDS             6148..7437
                     /gene="rsmB"
                     /locus_tag="OPV72_001385"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HCR9913738.1"
                     /translation="MKKQNNLRSLAAQAVELVVEQGQSLSNVLPPLQQKVADKDKALL
                     QELCFGVLRTLSQLEWLINKLMSRPMTGKQRTVHYLIMVGFYQLLYTRVPPHAALAET
                     VEGAVSIKRPQLKGLINGVLRQFQRQQETLLNEFATSDARFLHPGWLVKRLQNAYPTQ
                     WQRIIEANNQRPPMWLRVNRTHHTRDGWLGLLEDAGMKGYPHPDYPDAVRLETPAPVH
                     ALPGFAEGWVTVQDASAQGCAVFLAPQNGEHILDLCAAPGGKTTHILEVAPEADVLAV
                     DIDEQRLSRVYDNLKRLGMKATVKQGDGRYPAQWCGEQQFDRILLDAPCSATGVIRRH
                     PDIKWLRRDRDIAELAQLQAEILDAVWPRLKPGGTLVYATCSVLPEENRDQIKAFLQR
                     TPDAALSETGTPDQPGQQNLPGGEEGDGFFYAKLIKK"
     gene            7459..8835
                     /gene="trkA"
                     /locus_tag="OPV72_001386"
     CDS             7459..8835
                     /gene="trkA"
                     /locus_tag="OPV72_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004125888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HCR9913739.1"
                     /translation="MKIIILGAGQVGGTLAENLVGENNDITVVDTNGERLRSLQDKFD
                     LRVVQGHGSHPRVLREAGADDADMLVAVTSSDETNMVACQVAYSLFNTPNRIARIRSP
                     DYVRDADKLFHSEAVPIDHLIAPEQLVIDNIYRLIEYPGALQVVNFAEGKVSLAVVKA
                     YYGGPLIGNALSTMREHMPHIDTRVAAIFRHDRPIRPQGSTIVEAGDEVFFIAASQHI
                     RAVMSELQRLEKPYKRIMLVGGGNIGAGLARRLEKDYSVKLIERDQQRAAELAEKLQN
                     TIVFFGDASDQELLAEEHIDQVDLFIAVTNDDEANIMSAMLAKRMGAKKVMVLIQRRA
                     YVDLVQGSVIDIAISPQQATISALLSHVRKADIVGVSSLRRGVAEAIEAVAHGDESTS
                     RVVGRVIDEIKLPPGTIIGAVVRGNDVMIANDNLRIEQGDHVIMFLTDKKFITDVERL
                     FQPSPFFL"
     gene            8977..9390
                     /gene="mscL"
                     /locus_tag="OPV72_001387"
     CDS             8977..9390
                     /gene="mscL"
                     /locus_tag="OPV72_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large-conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HCR9913740.1"
                     /translation="MSFIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPP
                     LGLLIGGIDFKQFAFTLREAQGDIPAVVMHYGVFIQNVFDFVIVAFAIFVAIKLINRL
                     NRKKAEEPAAPPAPSKEEVLLGEIRDLLKEQNNRS"
     gene            complement(9326..9595)
                     /locus_tag="OPV72_001388"
     CDS             complement(9326..9595)
                     /locus_tag="OPV72_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alternative ribosome-rescue factor A"
                     /protein_id="HCR9913741.1"
                     /translation="MSRYQHKKGQIKDNAIEALLHDPLFRQRVEKNKKGKGSYLRKGK
                     HGNRGNWEASGKKVSDFFTTGLLLIKNGYFVLSADRGFRPITLPL"
     gene            complement(9654..10079)
                     /gene="zntR"
                     /locus_tag="OPV72_001389"
     CDS             complement(9654..10079)
                     /gene="zntR"
                     /locus_tag="OPV72_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Zn(2+)-responsive transcriptional regulator"
                     /protein_id="HCR9913742.1"
                     /translation="MYRIGELAKLADVTPDTIRYYEKQQMMDHEVRTEGGFRLYTEND
                     LQRLKFIRYARQLGFTLESIRELLSIRIDPEHHTCQESKSIVQERLQEVEARIAELQT
                     MQRSLQRLNDACCGTAHSSVYCSILEALEQGASGAKSVC"
     gene            complement(10090..10458)
                     /locus_tag="OPV72_001390"
     CDS             complement(10090..10458)
                     /locus_tag="OPV72_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1992 domain-containing protein"
                     /protein_id="HCR9913743.1"
                     /translation="MWLLDQWAERHIIEAQRKGEFDNLPGRGEPLILDDDSHVPAELR
                     AGYRLLKNAGCLPPELEQRRDAIQLLDILNSIREDDPQYHQVSRQLSLLELKLRQAGL
                     STDFLHGEYAEKLLHKINDN"
     gene            complement(10565..10948)
                     /gene="rplQ"
                     /locus_tag="OPV72_001391"
     CDS             complement(10565..10948)
                     /gene="rplQ"
                     /locus_tag="OPV72_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HCR9913744.1"
                     /translation="MRHRKSGRQLNRNSSHRQAMFRNMAGSLVRHEIIKTTLPKAKEL
                     RRVVEPLITLAKTDSVANRRLAFARTRDNEIVAKLFNELGPRFASRAGGYTRILKCGF
                     RAGDNAPMAYIELVDRSEKTEAAAE"
     gene            complement(10989..11978)
                     /gene="rpoA"
                     /locus_tag="OPV72_001392"
     CDS             complement(10989..11978)
                     /gene="rpoA"
                     /locus_tag="OPV72_001392"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005970247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HCR9913745.1"
                     /translation="MQGSVTEFLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALR
                     RILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTL
                     NKSGIGPVTAADITHDGDVEIVKPQHVICHLTDENASISMRIKVQRGRGYVPASTRIH
                     SEEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDPEEAIR
                     RAATILAEQLEAFVDLRDVRQPEVKEEKPEFDPILLRPVDDLELTVRSANCLKAEAIH
                     YIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLENWPPASIADE"
     gene            complement(12004..12624)
                     /gene="rpsD"
                     /locus_tag="OPV72_001393"
     CDS             complement(12004..12624)
                     /gene="rpsD"
                     /locus_tag="OPV72_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004410410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HCR9913746.1"
                     /translation="MARYLGPKLKLSRREGTDLFLKSGVRAIDTKCKIGQAPGQHGAR
                     KPRLSDYGVQLREKQKVRRIYGVLERQFRNYYKEAARLKGNTGENLLALLEGRLDNVV
                     YRMGFGATRAEARQLVSHKAIMVNGRVVNIASYQVSPNDVVSIREKAKKQSRVKAALE
                     LAEQREKPTWLEVDAGKMEGTYKRKPERSDLSADINEHLIVELYSK"
     gene            complement(12658..13047)
                     /gene="rpsK"
                     /locus_tag="OPV72_001394"
     CDS             complement(12658..13047)
                     /gene="rpsK"
                     /locus_tag="OPV72_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HCR9913747.1"
                     /translation="MAKAPVCARKRVRKQVSDGVAHIHASFNNTIVTITDRQGNALGW
                     ATAGGSGFRGSRKSTPFAAQVAAERCADAVKEYGIKNLEVMVKGPGPGRESTIRALNA
                     AGFRITNITDVTPIPHNGCRPPKKRRV"
     gene            complement(13064..13420)
                     /gene="rpsM"
                     /locus_tag="OPV72_001395"
     CDS             complement(13064..13420)
                     /gene="rpsM"
                     /locus_tag="OPV72_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019935869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HCR9913748.1"
                     /translation="MARIAGINIPDQKHAVIALTSIYGVGKTRSKAILAAAGIAENVK
                     ISELSEEQIDTLRDEVAKFVVEGDLRREISMSIKRLMDLGCYRGLRHRRGLPVRGQRT
                     KTNARTRKGPCKPIKK"
     gene            complement(13567..13683)
                     /gene="rpmJ"
                     /locus_tag="OPV72_001396"
     CDS             complement(13567..13683)
                     /gene="rpmJ"
                     /locus_tag="OPV72_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020322760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HCR9913749.1"
                     /translation="MKVRASVKKLCRNCKIVKRDGVIRVICSAEPKHKQRQG"
     gene            complement(13715..15046)
                     /gene="secY"
                     /locus_tag="OPV72_001397"
     CDS             complement(13715..15046)
                     /gene="secY"
                     /locus_tag="OPV72_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004868351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HCR9913750.1"
                     /translation="MAKQPGLDFQSAKGGLGELKRRLLFVIGALIVFRIGSFIPIPGI
                     DAAVLAKLLEQQRGTIIEMFNMFSGGALSRASIFALGIMPYISASIIIQLLTVVHPTL
                     AEIKKEGESGRRKISQYTRYGTLVLAIFQSIGIATGLPNMPGMQGLVMNPGFAFYFTA
                     VVSLVTGTMFLMWLGEQITERGIGNGISIIIFAGIVAGLPPAIAHTIEQARQGDLHFL
                     VLLLVAVLVFAVTFFVVFVERGQRRIVVNYAKRQQGRRVYAAQSTHLPLKVNMAGVIP
                     AIFASSIILFPATIASWFGGGTGWNWLTTISLYLQPGQPLYVLLYASAIIFFCFFYTA
                     LVFNPRETADNLKKSGAFVPGIRPGEQTAKYIDKVMTHLTLVGALYITFICLIPEFMR
                     DAMKVPFYFGGTSLLIVVVVIMDFMAQVQTLMMSSQYESALKKANLKGYGR"
     gene            complement(15054..15488)
                     /gene="rplO"
                     /locus_tag="OPV72_001398"
     CDS             complement(15054..15488)
                     /gene="rplO"
                     /locus_tag="OPV72_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011095501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HCR9913751.1"
                     /translation="MRLNTLSPAEGSKKAGKRLGRGIGSGLGKTGGRGHKGQKSRSGG
                     GVRRGFEGGQMPLYRRLPKFGFTSRKAAITAEVRLSDLAKVEGGVVDLNTLKAANIIG
                     IQIEFAKVILAGEVTTPVTVRGLRVTKGARAAIEAAGGKIEE"
     gene            complement(15492..15671)
                     /gene="rpmD"
                     /locus_tag="OPV72_001399"
     CDS             complement(15492..15671)
                     /gene="rpmD"
                     /locus_tag="OPV72_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012147215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HCR9913752.1"
                     /translation="MAKTIKITQTRSAIGRLPKHKATLLGLGLRRIGHTVEREDTPAV
                     RGMVNAVSFMVKVEE"
     gene            complement(15675..16178)
                     /gene="rpsE"
                     /locus_tag="OPV72_001400"
     CDS             complement(15675..16178)
                     /gene="rpsE"
                     /locus_tag="OPV72_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004106339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HCR9913753.1"
                     /translation="MAHIEKQAGELQEKLIAVNRVSKTVKGGRIFSFTALTVVGDGNG
                     RVGFGYGKAREVPAAIQKAMEKARRNMINVALNNGTLQHPVKGVHTGSRVFMQPASEG
                     TGIIAGGAMRAVLEVAGVHNVLAKAYGSTNPINVVRATIDGLENMNSPEMVAAKRGKS
                     VEEILGK"
     gene            complement(16193..16546)
                     /gene="rplR"
                     /locus_tag="OPV72_001401"
     CDS             complement(16193..16546)
                     /gene="rplR"
                     /locus_tag="OPV72_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005970258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HCR9913754.1"
                     /translation="MDKKSARIRRATRARRKLKELGATRLVVHRTPRHIYAQVIAPNG
                     SEVLVAASTVEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYHGR
                     VQALADAAREAGLQF"
     gene            complement(16556..17089)
                     /gene="rplF"
                     /locus_tag="OPV72_001402"
     CDS             complement(16556..17089)
                     /gene="rplF"
                     /locus_tag="OPV72_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003031129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HCR9913755.1"
                     /translation="MSRVAKAPVVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVK
                     HADNALTFGPRDGYADGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGNV
                     VNLSLGFSHPVDHQLPAGITAECPTQTEIVLKGADKQVIGQVAADLRAYRRPEPYKGK
                     GVRYADEVVRTKEAKKK"
     gene            complement(17102..17494)
                     /gene="rpsH"
                     /locus_tag="OPV72_001403"
     CDS             complement(17102..17494)
                     /gene="rpsH"
                     /locus_tag="OPV72_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HCR9913756.1"
                     /translation="MSMQDPIADMLTRIRNGQAANKAAVTMPSSKLKVAIANVLKEEG
                     FIEDFKVEGDTKPELELTLKYFQGKAVVESIQRVSRPGLRIYKRKDELPKVMAGLGIA
                     VVSTSKGVMTDRAARQAGLGGEIICYVA"
     gene            complement(17528..17833)
                     /gene="rpsN"
                     /locus_tag="OPV72_001404"
     CDS             complement(17528..17833)
                     /gene="rpsN"
                     /locus_tag="OPV72_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005599304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HCR9913757.1"
                     /translation="MAKQSMKAREVKRVALADKYFAKRAELKAIISDVNATDEDRWNA
                     VLKLQTLPRDSSPSRQRNRCRQTGRPHAFLRKFGLSRIKVREAAMRGEIPGLKKASW"
     gene            complement(17848..18387)
                     /gene="rplE"
                     /locus_tag="OPV72_001405"
     CDS             complement(17848..18387)
                     /gene="rplE"
                     /locus_tag="OPV72_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HCR9913758.1"
                     /translation="MAKLHDYYKDEVVNKLMTEFNYNSVMQVPRVEKITLNMGVGEAI
                     ADKKLLDNAAADLTAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFER
                     LITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRGLDITITTTA
                     KSDEEGRALLAAFDFPFRK"
     gene            complement(18402..18716)
                     /gene="rplX"
                     /locus_tag="OPV72_001406"
     CDS             complement(18402..18716)
                     /gene="rplX"
                     /locus_tag="OPV72_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HCR9913759.1"
                     /translation="MAAKIRRDDEVIVLTGKDKGKRGKVKNVLSSGKVIVEGINLVKK
                     HQKPVPALNQPGGIVEKEAAIQVSNVAIFNTATGKADRVGFRFEDGKKVRFFKSNSET
                     IK"
     gene            complement(18727..19098)
                     /gene="rplN"
                     /locus_tag="OPV72_001407"
     CDS             complement(18727..19098)
                     /gene="rplN"
                     /locus_tag="OPV72_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015817037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HCR9913760.1"
                     /translation="MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYAGVGDIIKITIK
                     EAIPRGKVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVILNNNSEQPIGTRIFGP
                     VTRELRNEKFMKIISLAPEVL"
     gene            complement(19262..19516)
                     /gene="rpsQ"
                     /locus_tag="OPV72_001408"
     CDS             complement(19262..19516)
                     /gene="rpsQ"
                     /locus_tag="OPV72_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006817275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HCR9913761.1"
                     /translation="MTDKIRTLQGRVVSDKMEKSIVVAIERFVKHPIYGKFIKRTTKM
                     HVHDENNECGIGDVVEIRECRPLSKTKSWTLVRVVEKAVL"
     gene            complement(19516..19707)
                     /gene="rpmC"
                     /locus_tag="OPV72_001409"
     CDS             complement(19516..19707)
                     /gene="rpmC"
                     /locus_tag="OPV72_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000644743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HCR9913762.1"
                     /translation="MKAKELREKSVEELNTELLNLLREQFNLRMQAASGQLQQSHLLK
                     QVRRDVARVKTLLTEKAGA"
     gene            complement(19707..20117)
                     /gene="rplP"
                     /locus_tag="OPV72_001410"
     CDS             complement(19707..20117)
                     /gene="rplP"
                     /locus_tag="OPV72_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017805229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HCR9913763.1"
                     /translation="MLQPKRTKFRKMHKGRNRGLAAGADVSFGSFGLKAVGRGRLTAR
                     QIEAARRAMTRAVKRQGKIWIRVFPDKPITEKPLAVRMGKGKGNVEYWVALIQPGKVL
                     YEMDGVPEELAREAFKLAAAKLPIKTTFVTKTVM"
     gene            complement(20130..20831)
                     /gene="rpsC"
                     /locus_tag="OPV72_001411"
     CDS             complement(20130..20831)
                     /gene="rpsC"
                     /locus_tag="OPV72_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001742302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HCR9913764.1"
                     /translation="MGQKVHPNGIRLGIVKPWNSTWFANTKEFADNLDSDFKVRQYLT
                     KELAKASVSRIVIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAGVPAQIN
                     IAEVRKPELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRLGAKGIKVEVSGRLGGA
                     EIARTEWYREGRVPLHTLRADIDYNTSEAHTTYGVIGVKVWIFKGEILGGMAAVEQPE
                     KPAAQPKKQQRKGRK"
     gene            complement(20849..21181)
                     /gene="rplV"
                     /locus_tag="OPV72_001412"
     CDS             complement(20849..21181)
                     /gene="rplV"
                     /locus_tag="OPV72_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000447526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HCR9913765.1"
                     /translation="METIAKHRHARSSAQKVRLVADLIRGKKVSQALDILTYTNKKAA
                     VLVKKVLESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSH
                     ITVVVSDR"
     gene            complement(21196..21474)
                     /gene="rpsS"
                     /locus_tag="OPV72_001413"
     CDS             complement(21196..21474)
                     /gene="rpsS"
                     /locus_tag="OPV72_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HCR9913766.1"
                     /translation="MPRSLKKGPFIDLHLLKKVEKAVESGDKKPLRTWSRRSTIFPNM
                     IGLTIAVHNGRQHVPVFVSDEMVGHKLGEFAPTRTYRGHAADKKAKKK"
     gene            complement(21491..22312)
                     /gene="rplB"
                     /locus_tag="OPV72_001414"
     CDS             complement(21491..22312)
                     /gene="rplB"
                     /locus_tag="OPV72_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001738551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HCR9913767.1"
                     /translation="MAVVKCKPTSPGRRHVVKVVNPELHKGKPFAPLVEKNSKSGGRN
                     NNGRITTRHIGGGHKQAYRIVDFKRNKDGIPAVVERLEYDPNRSANIALVLYKDGERR
                     YILAPKGLKAGDQIQSGVDAAIKAGNTLPMRNIPVGSTVHNVEMKPGKGGQLARSAGT
                     YVQIVARDGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAARWRGVRP
                     TVRGTAMNPVDHPHGGGEGRNFGKHPVTPWGVQTKGKKTRSNKRTDKFIVRRRSK"
     gene            complement(22330..22632)
                     /gene="rplW"
                     /locus_tag="OPV72_001415"
     CDS             complement(22330..22632)
                     /gene="rplW"
                     /locus_tag="OPV72_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HCR9913768.1"
                     /translation="MIREERLLKVLRAPHVSEKASTAMEKTNTIVLKVAKDATKAEIK
                     AAVQKLFEVEVEVVNTLVVKGKVKRHGQRIGRRSDWKKAYVTLKEGQNLDFVGGAE"
     gene            complement(22629..23234)
                     /gene="rplD"
                     /locus_tag="OPV72_001416"
     CDS             complement(22629..23234)
                     /gene="rplD"
                     /locus_tag="OPV72_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010304939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HCR9913769.1"
                     /translation="MELVLKDAQSALTVSETTFGRDFNEALVHQVVVAYAAGARQGTR
                     AQKTRAEVTGSGKKPWRQKGTGRARSGSIKSPIWRSGGVTFAARPQDHSQKVNKKMYR
                     GALKSILSELVRQDRLIVVEKFSVEAPKTKLLAQKLKDMALEDVLIITGELDENLFLA
                     ARNLHKVDVRDATGIDPVSLIAFDKVVMTADAVKQVEEMLA"
     gene            complement(23245..23874)
                     /gene="rplC"
                     /locus_tag="OPV72_001417"
     CDS             complement(23245..23874)
                     /gene="rplC"
                     /locus_tag="OPV72_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000579825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HCR9913770.1"
                     /translation="MIGLVGKKVGMTRIFTEDGVSIPVTVIEVEANRVTQVKDLANDG
                     YRAVQVTTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLAEGEEYTVGQSISVELFA
                     DVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKK
                     MAGQMGNERVTVQSLDVVRVDAERNLLLVKGGVPGATGCDLIVKPAVKA"
     gene            complement(23907..24218)
                     /gene="rpsJ"
                     /locus_tag="OPV72_001418"
     CDS             complement(23907..24218)
                     /gene="rpsJ"
                     /locus_tag="OPV72_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014268624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HCR9913771.1"
                     /translation="MQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPT
                     RKERFTVLISPHVNKDARDQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISL
                     G"
     gene            24598..25065
                     /gene="hopD"
                     /locus_tag="OPV72_001419"
     CDS             24598..25065
                     /gene="hopD"
                     /locus_tag="OPV72_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leader peptidase HopD"
                     /protein_id="HCR9913772.1"
                     /translation="MFVALPFLIFYASFSLLLGIYDARTGLLPDRFTCPLLWGGLLYH
                     QICLPERLPDALWGAIAGYGGFALIYWGYRLRYQKEGLGYGDVKYLAALGAWHCWETL
                     PLLVFLAAMLACGRFGVALLVRGKSALINPLPFGPWLAVAGFITGWKVFFPDG"
     gene            complement(25062..25538)
                     /gene="bfr"
                     /locus_tag="OPV72_001420"
     CDS             complement(25062..25538)
                     /gene="bfr"
                     /locus_tag="OPV72_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterioferritin"
                     /protein_id="HCR9913773.1"
                     /translation="MKGDVKIINYLNKLLGNELVAINQYFLHARMFKNWGLTRLNDVE
                     YHESIDEMKHADKYIERILFLEGIPNLQDLGKLGIGEDVEEMLRSDLRLELEGAKDLR
                     EAIAYADNVHDYVSRDMMIEILADEEGHIDWLETELDLIAKLGMQNYLQSQIKVTD"
     gene            complement(25611..25805)
                     /gene="bfd"
                     /locus_tag="OPV72_001421"
     CDS             complement(25611..25805)
                     /gene="bfd"
                     /locus_tag="OPV72_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterioferritin-associated ferredoxin"
                     /protein_id="HCR9913774.1"
                     /translation="MYVCLCNGISDKKIRQAVRQFHPQSFQQLRKFIPVGNQCGKCIR
                     AAREVMQDELTQMPEFKEIA"
     gene            complement(25990..>26361)
                     /gene="tuf"
                     /locus_tag="OPV72_001422"
     CDS             complement(25990..>26361)
                     /gene="tuf"
                     /locus_tag="OPV72_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312217.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HCR9913775.1"
                     /translation="GENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKD
                     EGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGL
                     RFAIREGGRTVGAGVVAKVLG"
BASE COUNT         6392 a         6996 c         6371 g         6602 t
ORIGIN      
        1 cccatttttt tgcacaagcg ttttttggat cttttttctg tttgttgatt tttcatccct
       61 ttcgctccat tcctgcgcaa agtggcgatt ttttgatgct atctcccctt gcacaacgcc
      121 gttaaagcaa ccaaagtctt catgactatt catttatgat gaggtagaca tgtctgacac
      181 attacgtcct tataaggatc tttttcctga aatcggtcag cgcgtgatga tcgataccag
      241 cagcgtggtt attggcgatg tccgtctggc ggatgatgtc gggatctggc cgcttgtggt
      301 gattcgcggc gatgtgaatt acgttgcgat aggggctcgt acgaacattc aggatggcag
      361 cgttcttcac gtaacccaca agtctccatc caatccacac ggcaacccat taatcattgg
      421 cgaagatgtt accgttggcc ataaagttat gctgcacggc tgtaccatcg gtaaccgcgt
      481 actggtcggt atgggctcca ttgtgctgga tggcgcgata atagaagatg acgtaatgat
      541 tggcgcggga agcctggtgc cgcagcacaa acggctggaa agcggctatt tatatcttgg
      601 cagtccggta aaacagatcc gccccctgag cgatgctgag agatcgggcc tgcagtactc
      661 cgccaataac tatgtaaaat ggaaagacga ctatctttct caggataacc atatccaacc
      721 gtgatcgtct tcctgctggg ccaggattaa tgcttcagcc tcttcttcca ggtcccagcg
      781 atactcacga aaaatggcca gccattgctc cgctgtttct ccaccaaagc gatacgccag
      841 tacatctttt tttatcgcac acgtgatttg catcccattg accagggcgg gaaagatgat
      901 agcgctggcg gcagtatccc attcttcgcg gtcagggaat tgtatggcct ggttcacgct
      961 aataattcct gctgtagcag cttaatcact ggctcgacct gcggtaatac accgtgccaa
     1021 agcaaaacgg catgtgcagc ctgccccacc agcattccca gcccatctgc gtagcgtttc
     1081 gcgccctgtt gtacacacca ggagagaaat ggcgtattcc ctttttgata gaacatgtca
     1141 tagcaacaga gggaaggatg aataagtgac gccggaatcg ccgggatttc gccccgtatg
     1201 ccgctggagg tcgcattaat aatcaggtca aactcacaac catccagctt gtccatatcc
     1261 atagcatgaa cgctgccggt atgagcaaag attttcgcca acgcttcggc acgtgaagct
     1321 gtacggttag tgatagtgac cgcacaatcc aaagaaagca ggggtaacag cacgccccgg
     1381 gatgcgccgc ccgcgccaat cagcaaaata cgcaatcctg ggcggataaa atttaaacgt
     1441 tcgagatcgc ttaataaacc gataccgtca gtattgtcgc caagcaaacg accatcttcc
     1501 agccgtttta atgtattgac ggctcccgcc agcgatgctc gttccgttaa ctcatccgaa
     1561 cgcgcaaacg cctcctcttt aaaaggtact gtgatgtttg cgccttttcc ccctgccgcg
     1621 aaaaaggcat caagcgtatt aatgaaatta ttaatggggg ccagcacgcg accatagggg
     1681 tgaacaatat ctagctgctg agcaaattgc tgatgaataa atggcgattt gctgtgcgca
     1741 atcggatttc caaaaacagc ataggcttcc atcatattac ccctgtcgaa atagttcgcc
     1801 cgtcagagca tcgcggattt ctgaaggatt taaacgccca cccgttgcgc cttcaaccac
     1861 cggaaaatca tcgccaaatt gcgcacgcac ctcttcaacg gtacggcatg gcggtaatcc
     1921 gctcagattg gcgctggtgg aaaccagcgg tttgccatac gcattgcata gcgcgaccac
     1981 cagcgggtgg ttggtaacac gaacggccag ggaatcaaaa cgtcccgtga gccaccgcgg
     2041 cgttgtcgcg ggcgcaggaa aaacaaacgt taccggcccg ggccagcaat caaataccgc
     2101 tttacgctgt gcggcggtaa gtatgctgtc atcaatataa ggttttaact gctcaaagct
     2161 ggcggcaatc aaaatgagtc ccttatcgac gggccgttgt tttaacgcca gcaggcgcgt
     2221 aacggctgtt tcactatcgg gatcgcagcc gacgccgaaa acggcttctg ttggataagc
     2281 gatgacattt tctttattca ggagatctac caccgcggcg ctagatcctg ttggcaggtt
     2341 attattcact tgtttattcc accggaaccg gctttccaca ttgtttactg gcgcaaaagc
     2401 gcttcacgcc ctgcgcggtt ttcttttcga tgagtagcga ataatggcac tcggggcatt
     2461 cccccgcaac cggtgtgaag ttaatgacga actgacattc cgggtagcga tcgcaggaat
     2521 gaaagatttt accgtaacga gaacggcgct ggaccaaatg tccttgctgg caggctggac
     2581 aggcaatcgc cgtttcatcc ggtttatcaa taaccactgt atgttcacat tgcggatact
     2641 gactgcatcc gatgaacatg ccaaagcgcc cctgacgcag caccagtacg gcgccacact
     2701 caggacacag ttgcccctcc agaattttaa cgatatgtcc gtccgcctga cttttcagcg
     2761 gacgaacgta atcgcattcc ggatagcgag aacagccgag aaacggacca tgtttcccgg
     2821 aacgaattac cagttcggcc ccgcactgcg ggcagggctc atttttacgc accgaaaaca
     2881 gtgctgattt agccatattc actcatgcag cattaacacc tatcaatgca gcataccttc
     2941 atttacctca aagagtaatt cttccatttg ctgataggcg ttttcacagc ccggaatgtt
     3001 gaataacacc atcaaaataa cccatttcaa gtcttccagg tcaaactctg cggtatccag
     3061 cgccagcaca cgctcaatca ccatttctcg tgtttcgagg tttagcacct gaatctgctc
     3121 aaggaataac aggaaccccc ggcaactggc atcaagcctt tcacattctt caaccgtata
     3181 aatgcgcatt gaaagagggt cggaagcaag ttgcatgggt tccgcgaggc catcctgata
     3241 gtcagcgagt ttttccagcc acagcagcgc attgtagatg tcttcgcgat caaacccagc
     3301 gtcggtgaga tcacgctcca gtctgtcctg atccacgcgc agctcggctt cgttatggat
     3361 gtatgtttca aacaaataca ttagtacgtc gaacatggct tgccctcctt aatcggacat
     3421 agccgccggg tacagctgcg atccatcctg ctaactccag ttcgagtagc tgagccacta
     3481 ccgctggcac aggttggccg gcacgttcag cgacgacgtc aacaggtgtt acctcatctc
     3541 ctacgttagc caggagctca ggaaatggca atgccgcctc atcctgattt agtgaataaa
     3601 gtgaattttc cgccgtagtt ggcaaccagt gtaagccgta ttgcaaattt tccagaatat
     3661 cctccggcgt cgtcacaagc gtggcccctt gtttaattaa ccagtgcgtg ccttcgcttc
     3721 ccggactacc gatagggcct ggtaatgcaa aaacgtcccg cccctgttca agcgcgcagc
     3781 gcgccgtcac caacgaaccg ctgcgcaacg ccgcctcaat caccagtacg cctttgctca
     3841 gtccgctgat gatacggttt ctgcgaggaa aattttgcga tagcggaggc gttgaaagcg
     3901 gaaattctga gaccactgcg ccgccagtgg caatcaagtt ttcagccagc atggcatgtc
     3961 ggcgaggata aatctttgcc aagccattcc ctaacaccgc tacacttttt ccccccatac
     4021 tcatcgcggc gttgtgtgct acgccatcaa ttcctcgggc aaggccgctg gtgatcgtca
     4081 aaccgctttt cgcaaggctt tcgcaaagca gacgtcccca gcgttctcca taccaggagt
     4141 ggctccggct cccgacgacg gcaagttggc aggtatgcag acaggcagga tcgccgtcaa
     4201 taaaaatagc gccgggataa tcgtcaatag cacgcagttg aggaggataa atctcactat
     4261 ccgcacacag aaaatggtgc tgcggtagtt caagccagcg taacgtctca tcaagcacac
     4321 ctgctggaag ctgtaaaaaa cgttcagctt gccgcgcagt aagaccagcc tcctgaaggt
     4381 gcgtgcgatt tatctgaggc tggcgaataa gcgaattcgc catgttcaac atcgcctcgc
     4441 cataaaggtc gccgacgtac attaaacgta accaaatttc ggtacgggcc atcctttccc
     4501 tcccctgcca caagcagtct gaacaatctt tgcgattggt cactgatgct gtcaatcagg
     4561 tggggatttg tctagaatag aggtaataat cttttcaact cctgaacaca actctggata
     4621 attatgtcag ttttgcaagt gttacatatt ccggacgagc gccttcgcaa agtcgcaaag
     4681 ccggttgaag aagtgaatgc agaaattcag cgtatcgtcg atgatatgtt cgaaacgatg
     4741 tacgcggaag aaggtatcgg tctggccgca acgcaggtcg atatccacca gcggatcatc
     4801 gtgattgacg tttcggaaaa ccgcgacgag cgcctggtac tcattaaccc ggaattgctg
     4861 gagaaaagtg gcgaaacggg tatagaagaa ggctgtctgt cgatcccgga acagcgcgct
     4921 ttagtgccgc gcgccgagaa agtgaaaatc cgcgcgctgg atcgcaacgg caacccgttt
     4981 gagcttgaag cggatggttt gctggcaatc tgcattcagc atgagatgga tcacctggtc
     5041 ggtaaactgt ttatcgatta tttgtcgccg ctgaagcaac aacgtattcg tcagaaagta
     5101 gaaaaactcg accgcctgaa cgcccgggct taaaggacaa gaaccaacgt gtcagattca
     5161 ctacgtatta tttttgcggg tacacctgac tttgcagcgc gtcatctcga cgcgctgtta
     5221 acttctggac ataacattgt cggcgtattt acccaacccg atcgtccagc aggtcgcggc
     5281 aaaaagttga tgcccagccc ggtaaaagtg ctggcggaag aaaaaggcct gcccgttttc
     5341 cagcccgtgt cgcttcgtcc tcaggaaaac cagcatctgg tggctgactt acatgccgac
     5401 gtcatggttg tcgtagcata tggtctgatt ctcccaaagg cagtgctgga tatgccccgt
     5461 ctcggatgta tcaacgttca cggttcgctg cttccacgct ggcgcggcgc ggcgcctatt
     5521 cagcgctcac tctgggcagg cgatgcggaa accggcgtca caattatgca gatggatgta
     5581 gggctggata ccggcgacat gctgtataaa cttgcgtgcc cgattaccgc agaagatacc
     5641 agtggctcac tgtataataa gttggctgaa cttggcccac aggggttaat taccacacta
     5701 aaacaactgg cggacggcac agcgacgcct gaagcgcaga atgaagcgct ggtcactcat
     5761 gcggaaaagc tcagtaaaga agaagcgcgt atcgactggt ctctctccgc agcacagctg
     5821 gagcgttgca ttcgcgcctt taatccgtgg ccaatgagct ggctggaaat cgacggccag
     5881 ccggtaaaag tctggcaggc atccgtcatt gaggacgcca cgcagtcgct gccgggaacc
     5941 attctggccg cgacgaaaca gggcattcag gttgcaacag gcaaggggat attaaatttg
     6001 ctttcgcttc agcctgccgg caaaaaagcg atgagcgccc aggatctgtt aaattcacgc
     6061 cgggaatggt ttatccctgg taaccgcctt gcctgacggt cacgtcttta tacgcccggt
     6121 gttaccgggc atttttattt tatacatatg aaaaaacaaa acaatttacg tagtctggca
     6181 gcacaggccg ttgaactggt cgtcgaacag ggacaatcat taagtaatgt gctcccgccg
     6241 ctgcaacaaa aagtcgccga taaagacaaa gcgctacttc aggagctgtg ctttggcgtc
     6301 ctgcgcaccc tttcacagct ggaatggctg atcaataagc tgatgtctcg tccaatgacc
     6361 ggcaagcagc gtacagtgca ttacttaatt atggtcggct tttatcagtt gctgtacacc
     6421 cgcgtccctc cccatgcggc gctggctgaa accgttgaag gcgcggtctc catcaaacgt
     6481 ccgcagttga aagggttaat taacggcgtc ctgcgccagt tccagcgcca gcaggaaacg
     6541 ttgcttaatg agtttgcgac cagcgatgcg cgctttttac atcccggttg gctggtaaag
     6601 cgtttgcaaa atgcttaccc cacacagtgg caacgcatta ttgaagcgaa taaccagcgt
     6661 ccacctatgt ggctacgtgt aaatcgtaca caccacaccc gcgacggttg gcttggctta
     6721 cttgaagacg caggcatgaa gggatatccc catcccgatt atcccgacgc tgtgcgtctg
     6781 gaaacgccag ctccggtaca tgctttaccc ggttttgctg agggttgggt aactgtccag
     6841 gatgcctctg cgcagggatg tgcggttttt ctcgctcctc agaacggtga gcacatttta
     6901 gacttgtgcg ccgcgcccgg cggtaaaacc acgcatattc tcgaagtggc ccccgaagca
     6961 gacgtgttgg cggttgatat tgatgaacaa cggctctccc gcgtttacga caacctaaag
     7021 cgccttggga tgaaagcgac agttaaacaa ggggatggac gttatcccgc ccaatggtgc
     7081 ggcgagcagc agtttgaccg tattctgctg gatgcgccct gctccgcaac cggcgtcatt
     7141 cgccgtcatc cagatatcaa atggctgcgt cgcgatcgcg atatcgcgga actggcgcaa
     7201 ttacaggcgg aaattcttga tgccgtctgg ccgcgcctga agcccggcgg gacgctggtt
     7261 tatgccacct gttccgtact gccggaagaa aaccgcgatc agatcaaagc ctttttgcaa
     7321 cgcactcccg atgccgcgct cagcgaaacg ggaacacctg atcagccagg acagcaaaat
     7381 ctgccgggcg gcgaagaagg tgatgggttc ttttacgcta agctaatcaa gaagtgatga
     7441 gataacgggc cacgactgat gaaaattatc atactgggcg cagggcaagt tggtggaaca
     7501 ctggcggaaa acctggtcgg cgaaaacaac gacatcacgg tggttgatac caacggcgaa
     7561 cgattacgca gtttgcaaga taagttcgat ctacgcgtag ttcaggggca tggttcgcat
     7621 ccccgcgtgt tgcgcgaagc gggcgctgac gatgcggata tgctggtcgc tgtcaccagt
     7681 tcagatgaaa ctaatatggt tgcctgtcag gtagcctatt cactcttcaa caccccaaac
     7741 cgtatcgccc gcattcgctc cccggactat gttcgcgatg cggataaact ctttcattct
     7801 gaagcggttc cgattgatca tctgatcgcg ccggagcagt tggttatcga taatatttat
     7861 cgtctgatcg agtatccggg agcattacag gttgtaaact ttgccgaagg gaaagtcagt
     7921 ctggcagtag taaaagccta ctatggcggt ccactaatag gtaacgcgct ctcgacaatg
     7981 cgagagcata tgccgcatat cgatacccgc gttgccgcaa ttttccgtca tgacagacca
     8041 atccgtcctc agggctcgac tatcgtggaa gcaggggatg aagtcttctt tattgcggct
     8101 tcacagcata tccgtgcagt aatgagcgaa ttacagcgtc tggaaaaacc ctacaagcgc
     8161 atcatgctgg tgggcggcgg caatatcggc gccgggctgg caaggcgtct ggaaaaagac
     8221 tatagcgtta aattgatcga acgcgatcaa caacgcgccg cagaactggc tgagaagctg
     8281 caaaacacga tcgtcttttt tggcgacgct tccgatcagg aattgctggc ggaggagcat
     8341 attgatcagg tcgatctctt tatcgcagtc actaacgatg acgaagccaa tatcatgtcc
     8401 gcgatgttgg ctaagcggat gggcgccaaa aaagtgatgg tgctgattca gcgtcgagct
     8461 tatgtcgatc ttgtgcaggg tagcgttata gatattgcga tttctccgca gcaggccacc
     8521 atctctgcat tactgagcca tgtgcgtaaa gcagatatcg tcggcgtttc ctcactacgt
     8581 cgcggggttg ccgaagccat cgaagccgtc gcgcacggcg atgaaagcac ttcccgcgtg
     8641 gttggccgcg tcattgacga aataaaactg ccgccaggca ccattattgg cgcggtcgtt
     8701 cgcggtaatg atgtcatgat tgctaatgac aatttgcgca ttgaacaagg cgatcacgtc
     8761 attatgtttt tgaccgataa aaagtttatt accgacgtcg aacgtctgtt ccagccaagt
     8821 cctttcttcc tctaatttaa ggggcgctca ttcagcgccc tttttaattc cctttattta
     8881 tcaaggttta atttatttcg ctaaacagaa gccgtaaatg gaaaatgcct tagcatttgt
     8941 taaacttata acgtcagctg catagggaga ataaaaatga gttttattaa agaattccgc
     9001 gaattcgcga tgcgcgggaa tgttgtggat ttggcagtgg gtgtcattat tggcgcggca
     9061 ttcggtaaga ttgtttcttc actggttgcc gatatcatta tgccgccgtt gggattgtta
     9121 atcggcggga tcgactttaa acaatttgct tttacgttac gcgaagcgca gggagatatt
     9181 ccggcggtcg tcatgcatta cggcgtgttt atccagaacg tatttgattt tgtgattgtg
     9241 gcgtttgcta tctttgttgc cattaagctt atcaacagac tcaaccgtaa aaaagcagaa
     9301 gagccggcag ctccgcccgc gccttctaaa gaggaagtgt tattgggcga aatccgcgat
     9361 ctgctgaaag aacaaaataa ccgttcttaa taagcagaag gccagtggta aaaaagtcac
     9421 ttactttctt gccactggcc tcccagttcc cccggttacc gtgtttacct ttacgcagat
     9481 aacttccttt gcctttctta tttttttcaa cgcgttgcct gaaaagggga tcgtgtaaca
     9541 atgcctcgat ggcattgtcc tttatctgcc ctttcttatg ttgataacga ctcataatat
     9601 ctcccgtttg tataaattat acggcgcgag tgtagtcccg ccggttcaat aaatcaacat
     9661 actgatttcg ccccactggc cccctgttcc agggcttcca gaatggaaca atagacgcta
     9721 ctgtgggccg ttccgcaaca agcatcatta agcctttgta acgaacgctg catcgtttgc
     9781 agttccgcaa tcctggcttc aacctcctgc aatcgttctt gcacaatact ttttgactcc
     9841 tgacaggtat ggtgctcagg atcaattctg atcgataaaa gttcgcggat cgactcaagc
     9901 gtgaaaccca actgccgcgc ataacgaata aacttgagac gctgcagatc gttttcggta
     9961 tacagacgaa acccgccttc agtacgtacc tcatgatcca tcatctgctg tttttcatag
    10021 tagcgaatgg tatcaggcgt tacgtctgcc agctttgcca gctcaccaat gcgatacata
    10081 caagctccgt taattatcgt tgattttatg cagcagtttt tctgcatact caccgtgtaa
    10141 aaaatcggta ctcaacccag cctgccgaag ttttagttca agcagcgaga gctggcgact
    10201 aacctgatgg tattgagggt catcttcccg gatactgttg aggatatcaa gtaactgaat
    10261 agcgtctctg cgctgctcca gttcaggggg aagacagccc gcattcttca gtaagcgata
    10321 acccgcacga agttccgctg gcacatgaga atcatcatcc agaataagcg gttcgccgcg
    10381 gccaggcaga ttatcaaact cgcctttacg ctgtgcctcg ataatatgac gctctgccca
    10441 ctggtcaagt aaccacatac gtcgctccag ggattgaacg aaaagaatac aattattgta
    10501 gatatgtggg gttcaggagg atataaaaaa acccgccgaa gcgggttttt tacgttacta
    10561 cagattactc tgcagcagct tctgttttct ctgaacgatc aaccagctcg atgtatgcca
    10621 tcggcgcgtt gtcgcctgca cggaagccac acttcagaat gcgagtgtaa ccaccggcgc
    10681 ggctcgcgaa acgcgggccc agctcgttaa acagttttgc cacgatctcg ttatcacgag
    10741 tacgggcgaa tgccagacga cgattagcaa cgctatcagt cttggcaaga gtaatcagcg
    10801 gctcaactac gcgacgcagc tctttcgctt taggcagggt cgtcttgatg atttcatgac
    10861 gaaccagtga acctgccatg ttgcggaaca tagcctggcg atggctgctg ttgcggttca
    10921 gttgacgacc actcttacga tggcgcatga ccttatcctt ctcagtaaaa ccttaacctg
    10981 tgatccggtt actcgtcagc gatgcttgcc ggtggccagt tttccaggcg catacccaga
    11041 gacagtccac gggaagccag cacgtcttta atctcggtaa gagatttttt acccaggtta
    11101 ggcgtcttaa gaagctcaac ctcggtacgc tgtaccagat caccgatata gtggatagct
    11161 tctgccttga ggcagttagc agagcggaca gtcaattcca gatcgtcaac agggcgcagc
    11221 aggatcggat cgaattctgg tttctcttct ttcacttccg gttgacgtac atcacgtaaa
    11281 tcaacgaaag cttccagttg ttcagccagg atggttgccg cacgacgaat cgcctcttca
    11341 ggatcgattg tgccgttggt ttccatttcg atgaccagct tgtccaggtc ggtacgctgt
    11401 tctacacgcg ctgcttcaac attgtaggca atacgctcta cagggctgta gcaggcgtcg
    11461 accagcagac ggccgattgg gcgctcatct tcttccgaat gaattcgggt agaagccggc
    11521 acataaccac gaccgcgctg aactttgata cgcatactaa tagacgcgtt ttcatcggtc
    11581 aggtggcaga tcacgtgctg cggcttgacg atttcgacat ccccatcatg ggtgatatcg
    11641 gctgcagtca cagggccaat gccagattta ttcaaggtaa gaataacttc atctttaccc
    11701 tgaactctca ccgccagccc tttcaggttg agcaggattt ccaggatgtc ttcctgaacg
    11761 ccttctttgg tgctgtactc atgtagtaca ccatcaatct caacctcggt caccgcgcaa
    11821 cccggcatcg atgagagcag aatacggcgc agtgcgttac ccagagtatg gccgaagcca
    11881 cgctctaaag gctcaagggt caccttggcg tgcgtcgaac tcacttgctc gatatctacc
    11941 aggcgcggtt ttagaaactc tgtcacagaa ccctgcattg tgtcctctct ttggtactaa
    12001 gctttacttg gagtaaagct cgacgatcag gtgttcgtta atgtccgcag acagatcaga
    12061 acgctcaggc ttacgcttgt acgtaccttc catcttgcca gcatcaactt ccagccaggt
    12121 tggcttttca cgctgctcag ccagctccag agcggctttc acgcgagact gcttcttcgc
    12181 tttctcacga atgctaacaa cgtcattcgg actaacctga taagaagcga tgttaacaac
    12241 acgaccgttt accataattg ctttatggct aaccagctga cgtgcttctg cacgagtggc
    12301 gccgaagccc atacggtata caacgttgtc cagacgacct tccagcagag ccaacaggtt
    12361 ttcaccggtg ttgcctttca gacgtgctgc ttctttgtag tagttacgga actgacgctc
    12421 cagcacaccg taaatgcggc gaactttttg cttttcacgc aactgcacac catagtcaga
    12481 cagacgcggc ttacgcgcac cgtgctggcc aggagcttgt ccaattttac acttggtatc
    12541 gatcgcgcga acgccagact taaggaataa gtcggtgccc tcacgacggc tcagcttgag
    12601 cttaggaccc aaatatcttg ccattttctt tctccaacta acctggaaaa cgaagcgtta
    12661 tacgcgacgt tttttcggcg gacgacaacc gttatgaggg atcggagtca catcagtaat
    12721 attagtgatg cggaaaccag cggcgttcag agcacgaata gtagattcgc ggcctggacc
    12781 cggaccttta accataactt ccagattctt gataccgtat tctttcacgg cgtcagcgca
    12841 acgctctgct gcaacctgag ctgcaaacgg agtggatttg cgagaaccac ggaaaccgga
    12901 accaccggct gttgcccaac ccagcgcatt accctgacga tcggtaatag tcacgatggt
    12961 gttgttgaaa gaagcatgga tatgagccac gccgtcagag acttgttttc ttacacgttt
    13021 acgtgcgcaa actggtgcct ttgccattat tcaatcaccc cgattatttc ttgatcggtt
    13081 tgcacggacc cttacgggta cgagcgttgg tcttggtacg ctgaccgcga accgggagac
    13141 cacgacgatg acgcaaaccg cgatagcaac caagatccat caggcgcttg atgctcatgc
    13201 tgatttcacg gcgcagatca ccttcaacga caaatttggc aacttcgtca cgcagcgtgt
    13261 cgatttgttc ttcagacagc tcactgatct taacattttc agcgataccc gctgcagcca
    13321 ggatggcttt agaacgggtc ttgccgacac cgtagatcga agttaacgcg atcacggcgt
    13381 gtttctgatc aggaatgtta atgcctgcta tacgggccac tatgcactcc tactatttaa
    13441 tatgtacgta ccatgctgaa aagcccgttt tcaggatact caaatggaaa cgtacagaca
    13501 tacaaaagat tggctggcta atctagccag ctcaacccaa ctttgcaaga aaaatatgcg
    13561 aaaaaatcag ccttggcgct gtttatgctt cggctcggca ctgcaaatca cacggatgac
    13621 accatcacgc ttaacgattt tgcagttacg gcataatttc ttgacggaag cacgaacttt
    13681 catttttact ctccgtaact tctcaggcga ccaattaacg gccgtagcct ttcaggttcg
    13741 ccttcttcaa tgcagactca tactgactgg acatcatcag agtttgcact tgagccataa
    13801 agtccataat cacgacaaca acgataagca gtgaggtccc accgaagtag aacggcactt
    13861 tcattgcatc acgcatgaac tccgggatca ggcagataaa ggtaatatac agcgcaccaa
    13921 ccagggtcag gtgggtcatt actttatcga tatacttcgc cgtttgctct cccggacgaa
    13981 ttcctggtac aaatgcaccg gacttcttca ggttatctgc tgtttcacgc gggttgaaaa
    14041 ccaacgccgt gtagaagaaa cagaagaaga tgattgcaga cgcatagagt aacacataaa
    14101 gcggttgccc aggctgcaaa tacagcgaaa ttgttgtcag ccagttccaa ccagtaccgc
    14161 ccccgaacca tgacgctatg gtcgccggga acagaataat actggaagcg aagattgccg
    14221 ggattacccc cgccatattc actttcagcg gtaaatgtgt gctctgtgca gcatagacac
    14281 gacgaccttg ctgacgtttg gcgtagttta ccacaatacg gcgttgacca cgttcaacga
    14341 atactacaaa gaacgtcact gcaaatacta atactgcaac caacagcaac acgaggaagt
    14401 gcaggtcgcc ttgacgcgct tgctcgatag tatgggcaat ggctggcggg agtcccgcaa
    14461 cgataccagc gaagatgatg attgagatac cgttaccgat accgcgctca gtaatctgtt
    14521 cgccgagcca catcaggaac atggtccctg taaccagact tacaacagcg gtgaaataga
    14581 atgcaaagcc tggattcatc accaggccct gcataccagg catattcggc aaaccggtag
    14641 caataccgat cgactggaat atcgccagca ccagagtacc gtaacgggtg tactggctga
    14701 tcttacgacg accagactcc ccttctttct taatttctgc gagcgttgga tgaaccaccg
    14761 tcaacagctg gataatgatc gacgccgaaa tatacggcat gatccccagg gcaaagatag
    14821 aagcacggct gagagcacca ccagagaaca tgttaaacat ttcaatgatg gtgcctcgct
    14881 gttgctcaag cagtttggca agtacagcgg catcaatacc agggatcgga ataaaagagc
    14941 caatacggaa cacaatcagc gcgccgataa caaacagcag tctgcgtttc agctcaccta
    15001 agccaccttt ggcactttga aaatctaatc ccggttgttt agccatctgc tacttattcc
    15061 tcgattttac cgccagcagc ttcgatagca gcacgagcgc ctttagtaac acgcaggcca
    15121 cgaacagtta ccggagtagt gacttcgcca gccaggatca ctttcgcgaa ctcgatctgg
    15181 ataccgataa tgtttgccgc tttcagcgtg ttcaggtcta caacgccgcc ttctactttc
    15241 gccaggtcag acagacgaac ttcggctgta atcgctgctt tgcgagaagt gaagccgaat
    15301 ttcggcagac gacggtacag aggcatctga ccaccctcga aaccgcgacg tacgccaccg
    15361 ccagaacgag acttctgacc tttgtgacca cgaccaccgg ttttaccgag gccagaaccg
    15421 ataccacgac ccaggcgttt acccgccttt ttggagcctt cggccggaga cagagtattt
    15481 aaacgcatct cttactcctc aactttaacc atgaaggaaa ccgcgttgac cataccacga
    15541 acagcaggag tatcctcgcg ctctacggtg tggccaatac gacgcagacc caggccaagc
    15601 agcgttgcct tgtgtttcgg cagacgaccg attgcactgc gggtttgagt aattttaata
    15661 gtctttgcca tggtttattt ccccagaatt tcttcaacgg atttaccacg cttggcagcg
    15721 accatttctg gagaattcat attttccagg ccatcaatag ttgcacgaac cacgttgatc
    15781 gggttggtgg aaccgtatgc tttagccaga acgttatgaa ccccagcaac ttccagaacg
    15841 gcgcgcattg caccaccggc gatgataccg gtaccttcgg aagctggctg catgaataca
    15901 cgagaccccg tgtgaacacc tttaaccggg tgctgcaggg tgccgttgtt cagcgcgacg
    15961 ttaatcatat tgcgacgggc tttttccatc gctttctgga tcgctgctgg aacttcacgc
    16021 gctttaccgt aaccaaaacc tacgcgaccg ttaccatcgc ctactacagt cagagctgtg
    16081 aaggagaaaa tacgaccacc tttaacggtt ttagatacgc ggtttaccgc gatcagcttt
    16141 tcctgcagtt cgccagcttg tttttcgatg tgagccatct tacacctcta ccttagaact
    16201 gaaggccagc ttcacgggca gcatctgcca gtgcctggac acgaccatga tattggaacc
    16261 cggaacggtc aaaggacaca tctttgatgc ctttttccag agcgcgttca gcgacagctt
    16321 tacccacagc tgcagccgca tctttgttac cggtgtactt cagttgttca gcgatagctt
    16381 tttctacagt agaagcagct accagaactt cagaaccgtt cggtgcaatt acctgtgcgt
    16441 aaatatgacg cggggtacga tgtaccacca ggcgagttgc gcccagctct ttgagcttgc
    16501 ggcgtgcgcg ggtcgcacga cggatacgag cagatttctt atccatagtg ttaccttact
    16561 tcttcttagc ctctttggta cgcacgactt cgtcggcgta acgaacaccc ttgcctttgt
    16621 aaggctcagg acgacggtag gcgcgcagat ctgctgcaac ctggccgatc acctgcttat
    16681 cagcgccttt cagcacgatt tcagtttgag tcggacattc agcagtgata cctgccggca
    16741 gctgatggtc aaccgggtga gagaaaccta aagacaggtt tactacattc cctttaaccg
    16801 ctgcacgata acctacacca accagctgca gcttcttagt gaagccttcg gtaacaccga
    16861 taaccattga gttcagcagg gcacgcgcgg taccagcctg tgcccaaccg tctgcgtaac
    16921 catcacgcgg accgaaggtc agtgcattat ctgcatgttt aacttcaaca gcatcgttga
    16981 gagtacgagt cagctcgccg tttttacctt tgatcgtaat aacctgaccg ttgattttga
    17041 catcaacgcc ggcaggaaca acgaccggtg ctttagcaac acgagacatt ttttcctccg
    17101 attaggctac gtagcagata atttcgccac caagaccagc ctggcgcgct gcacgatctg
    17161 tcataacacc tttagaggta gaaacaactg cgatacccag accggccata actttcggca
    17221 gctcatcttt acgtttgtag atgcgcaggc ctgggcggct gacacgctga atgctttcta
    17281 caacagcttt accctggaaa tacttaagag tcagttccag ttccggcttg gtgtcgcctt
    17341 caactttaaa atcttcaata aaaccttctt ccttcagcac gttggcaatt gccactttca
    17401 gcttagagga aggcatggtg accgcagctt tgttcgcggc ctgaccgtta cggatacggg
    17461 tcagcatatc cgcgatcgga tcttgcatgc tcatctgtct ttactcccgt gattcaattg
    17521 gtgacaatta ccagctagcc tttttcagac ccggaatttc accgcgcata gcggcttcac
    17581 ggaccttaat acggctcaac ccgaacttcc gcaggaaagc gtgcggacga ccagtttgac
    17641 ggcagcggtt acgctgacgt gacgggctgg aatcacgcgg cagagtctgc agcttaagaa
    17701 ccgcattcca acgatcttcg tcggttgcgt tcacatcaga gatgatcgct ttcagttcag
    17761 cgcgtttcgc gaagtattta tcagctaaag ctacgcgttt tacttcgcgt gctttcattg
    17821 attgcttagc catttagtaa ccctacctta cttgcggaac gggaagtcaa aggcagccag
    17881 cagagcacgg ccttcttcgt cagatttcgc agtagtggta atggtaatat ccaaaccacg
    17941 aacgcggtcg actttatcgt agtcgatttc tgggaagatg atctgctcac ggacacccat
    18001 gctgtagtta ccacgaccgt cgaatgactt agcggacaag ccacggaagt cacggatacg
    18061 aggaacagca atagtgatca ggcgctcaaa gaactcccac atgcgttcgc cacgcagagt
    18121 tactttacag ccgatcggat agccctgacg gattttgaag cctgcaacag atttgcgtgc
    18181 tttggtgatc aacggttttt gaccggagat tgctgtcagg tctgctgctg cgttatccag
    18241 cagtttcttg tcagcgatcg cttcaccaac acccatgttc agggtgatct tctcgacccg
    18301 agggacttgc atgacagaat tgtagttaaa ctcagtcatg agtttgttaa ctacttcgtc
    18361 tttgtagtaa tcatgcagtt tcgccatcgt actactccaa attacttgat agtttcgctg
    18421 ttagacttga agaaacggac ttttttgccg tcttcgaatc taaagcctac acggtcagcc
    18481 ttgccggttg ccgtattgaa gattgcaacg ttagaaacct gaattgcagc ttctttttca
    18541 acgatgccgc ccggttggtt cagagccgga accggcttct ggtgtttctt aaccaggttg
    18601 ataccttcaa caatgacctt gccggaagac aggacattct taactttacc gcgtttacct
    18661 ttatctttac cggttaacac gataacttcg tcatcacgac ggattttcgc tgccatgatt
    18721 cgctccttag agtacttctg gtgccagaga gataattttc atgaacttct cgttacgaag
    18781 ttcacgagtt accggcccaa aaatacgcgt accgataggc tgctcgctgt tattgtttaa
    18841 aataacgcat gcattaccat cgaagcgaat gacagaaccg tccgggcgac gaacaccctt
    18901 cttggtgcgc accactaccg ccttcagcac atcacctttt ttgaccttac cacgcggaat
    18961 cgcttctttg atggtgatct taatgatgtc gcctacgcct gcgtagcgac ggtgcgagcc
    19021 acccagaacc ttgatacaca ttacgcgacg tgcaccggag ttgtcggcga cgttcagcat
    19081 agtctgttct tggatcattt tagtgctccg ctaatgtcaa ctactactga gacccgaaaa
    19141 tcaggtcgtt aaaaaaaccc catatcgagg gcgcggcatt ataacaccgc aaatcagata
    19201 tgggtagaaa aaataaacgg cccatcgctg agccgtttat tcgttgagaa tgcgtactgt
    19261 attacagaac cgctttctct acaacgcgaa ccagagtcca ggatttggtc ttggacagcg
    19321 gacggcattc gcggatttca accacgtcgc cgataccgca ttcgttgttc tcgtcatgta
    19381 cgtgcatttt ggtcgtacgc ttgatgaatt taccgtagat cgggtgtttc acaaaacgtt
    19441 cgatagcaac aacaatggat ttctccattt tgtcgctaac cacgcgacct tgcagagtac
    19501 ggattttatc ggtcattacg cacccgcctt ctcagtcagt aaagtcttaa cgcgtgcgac
    19561 atcacgacgc acttgcttca acaggtgaga ctgttgcagc tggccacttg cagcctgcat
    19621 acgcaggttg aactgctcac gcagcaggtt cagtagctcg gtgttcagct cttcaacgct
    19681 cttctcacgc agctcttttg ctttcattac atcaccgtct tagttacaaa ggtggtttta
    19741 atcggcagtt tcgctgctgc cagcttgaat gcttcacggg ccagctcttc cggtacgccg
    19801 tccatttcat acaggacttt acccggctga atcaaggcaa cccaatactc cacgttacct
    19861 ttacctttac ccatacgcac tgccagcggc ttttcagtga tcggtttgtc cgggaataca
    19921 cggatccaga tcttaccttg acgcttaact gcacgggtca tagcacgacg tgctgcttcg
    19981 atctgacggg cagtcagacg accacggcca acagctttca ggccgaagct gccgaagcta
    20041 acatccgcgc ctgcagccag accacggttg cggcctttgt gcattttacg gaattttgta
    20101 cgctttggtt gtaacatcag cgacgctcct tatttacggc ctttacgctg ctgctttttc
    20161 ggttgagcag ccggtttttc cggttgttca acagcagcca taccacccag gatctcgcct
    20221 ttgaagatcc acactttaac gccgattaca ccataagtgg tgtgcgcttc agaggtgttg
    20281 tagtcgatgt cagcacgcag agtgtgcagc ggtacgcgac cttcgcggta ccattcggta
    20341 cgtgcgattt ccgcgccgcc cagacggccg ctaacttcaa ctttgatacc tttagcgccc
    20401 agacgcatgg cgttctgtac agcacgcttc atcgcacgac ggaacataac gcgacgttcc
    20461 agctgagaag tgatgctgtc agcaaccagt ttagcgtcca gttcaggttt acgaacttcg
    20521 gcgatgttga tctgtgcagg aacgccagcg atatccgcta cgaccttacg cagtttttct
    20581 acgtcttcac cttttttacc gataacgata cccgggcgag cggtgtgaat agtcacacgg
    20641 atgctcttag ccggacgctc gataacgata cgagatacag acgctttagc cagttccttc
    20701 gtcaggtact gacgtacttt aaaatcgctg tccaggttgt cagcgaattc tttggtgttc
    20761 gcaaaccagg tagagttcca tggttttaca atacccaggc gaataccatt aggatgtact
    20821 ttctgaccca ttgctagtct ccagagtctc agcgatcgga cacaaccaca gtgatgtggc
    20881 tggtgcgctt caggatgcga tctgcacgac cttttgcacg cggcataatg cgcttcatgc
    20941 tcgggccttc gtctacgaaa attttcgtaa ctttcagatc gtcaatgtca gcgccatcgt
    21001 tgtgttcagc gttagcaatg gcagattcca gaactttctt gaccagtaca gccgctttct
    21061 tgttggtgta ggtcagaata tccagagcct gcgacacttt cttaccgcga atcaggtcag
    21121 caacaaggcg aaccttctga gcagaagaac gagcatggcg atgtttagcg atagtttcca
    21181 tctcttcctc ctaccttatt tcttcttcgc ttttttatca gcagcgtggc cgcgataagt
    21241 acgagtcggt gcgaattcac ccagtttgtg accgaccatt tcgtcggaaa caaataccgg
    21301 aacgtgctga cgaccattat ggacagcgat ggtcaaaccg atcatgttag gaaagatcgt
    21361 tgaacgacgg gaccaagtgc gcaggggctt cttgtctccg ctttccaccg ctttctctac
    21421 cttcttcagc aagtgcaggt caataaaagg acctttcttg agagaacgtg gcatggctta
    21481 tcctctaaaa ttatttgcta cggcgacgta cgatgaattt atcagtacgc ttgttgctgc
    21541 gggtcttctt acctttggtc tgaacgcccc acggagttac cgggtgctta ccaaagttac
    21601 gaccttcacc accaccatgt gggtggtcta ctgggttcat cgcagtaccg cgaacggtag
    21661 gacgaacgcc acgccagcgt gcagcacctg ctttacccag aacgcgcagc atatgctcag
    21721 cattgccaac ttcgcccagg gttgcacggc agtctgcttc gactttacgc atttcaccag
    21781 aacgcagacg cagggtgaca taagcgccat cgcgagcaac gatctgaacg taagtaccag
    21841 cggaacgcgc cagctgaccg cctttacctg gtttcatttc tacgttatga acggtagaac
    21901 caaccgggat attgcgcatc ggcagggtgt tgcctgcttt gattgcagca tcaacgccag
    21961 actgaatctg gtcgccagct ttcaggcctt tcggggccag gatgtaacgg cgttcgccgt
    22021 ctttgtacag aaccagcgcg atgttcgcgg aacggttcgg atcgtactca agacgttcaa
    22081 caactgccgg gataccgtct ttgttgcgtt tgaagtcaac aatacgataa gcctgtttgt
    22141 gaccaccacc gatatgacga gtggtgatac ggccattgtt gttacgacca ccggatttgc
    22201 tgtttttttc aaccagcgga gcaaaaggtt tgcccttgtg cagctctggg ttgaccactt
    22261 taacgacgtg gcgacgaccc ggagatgtcg gtttacattt aacaactgcc attgtattac
    22321 tcctccgact tactcagcgc cgccgacgaa gtccagattc tggccttctt tcagggtgac
    22381 gtaagctttt ttccagtcgc tacgacgacc gatacgctgt ccgtgacgtt taactttccc
    22441 tttaacgacc agggtgttaa cgacttcgac ttcgacttca aacagtttct gcacagcagc
    22501 tttgatttct gctttggtcg cgtctttagc aactttgaga acgatggtgt tggttttttc
    22561 catcgcagta gacgcttttt cagaaacgtg cggtgcgcgc agcaccttca gcagacgttc
    22621 ttcacgaatc atgccagcat ctcctcaact tgcttaacag catcagcagt cattacgact
    22681 ttgtcgaagg cgatcaggct aaccgggtcg ataccagtcg catcgcgtac gtcaaccttg
    22741 tgcaggttac gtgcggccag gaacaggttc tcgtccagct caccggtgat gatcagcaca
    22801 tcttccagag ccatgtcttt cagtttctgt gccagcagct tagttttcgg cgcttctaca
    22861 gagaacttct cgacaacgat cagacgatcc tgacgtacca gttcggacag gatgcttttc
    22921 agcgcgccgc ggtacatctt cttgttaact ttttgactgt ggtcctgcgg acgagcagcg
    22981 aaggtcacgc caccggaacg ccagatcggg ctcttgatag aacctgaacg cgcacggcca
    23041 gtgcctttct ggcgccacgg ttttttaccg gaaccagtta cttcagcacg agtcttctga
    23101 gcacgagtac cctgacgagc accagctgca taagcaacaa caacctggtg aaccagcgct
    23161 tcgttgaaat cacgaccgaa ggtagtttcg gaaacagtca gcgcgctctg cgcgtctttc
    23221 aatactaatt ccattgctat ccccttacgc cttcacagct ggtttaacga tcaggtcgca
    23281 accggttgca cccggaacac cacccttaac cagcagcagg ttgcgctcag cgtcaacgcg
    23341 tactacgtca aggctctgaa cggttacgcg ctcattaccc atctgacctg ccattttctt
    23401 gcctttgaac actttgcccg gagtctggtt ctgaccgata gaacccggaa cgcggtgaga
    23461 caaggagtta ccgtgagtag cgtcctgggt acggaagttc cagcgcttaa cggtaccagc
    23521 gaaaccttta cctttagagg taccggttac gtcaactttt ttaacgtcag caaacagttc
    23581 aacgctgatg ctctgaccta cggtgtattc ttcgccttca gccagacgga attcccacag
    23641 accacggcca gcttctacgc cagctttagc aaagtgaccc gcttccggct tggtgacacg
    23701 gttagctttt ttagcacccg tagtaacctg aacagcgcgg tagccatcgt tagccaggtc
    23761 tttaacctga gtaacacggt ttgcttcaac ttcgattacg gttactggga tagagacgcc
    23821 atcttcagtg aagatgcggg tcatacccac ttttttaccg actaaaccaa tcattgtatc
    23881 aacctctcaa tcgctcgatg acctgattaa cccaggctga tctgcacgtc tacaccggca
    23941 gctaggtcca gacgcatcag agcatcaacg gttttctcgg ttggctcaac gatgtcaacc
    24001 agacgcttgt gagtgcgaat ttcgtactga tcgcgcgcat ctttgttaac gtgcggagag
    24061 atcagaacgg taaagcgctc tttgcgggtc ggcagcggga tcggaccgcg aacctgcgca
    24121 ccagtgcgct tggcagtctc gacgatttcc gcggttgatt gatcgatcag acgatgatca
    24181 aacgctttca ggcggatacg gattctttgg ttctgcatga gaccagagct ccaattattt
    24241 tataaacgaa aatgattact cctcacaccc attacgattg atgggagagt gtaaccgttc
    24301 ttacgtagct ccccgattgg gagcattgtt aaatagccaa atcggctatt cgaggttcaa
    24361 atcgaacctg ccgtcaatta cgacaagccc gcgcattata cgtaaatctc agcctgacgc
    24421 aagtgtcgga tagaaattaa gcgctttatt cttatgcgag catgattcca gatggtacgc
    24481 atgggatggc gacgcgcatc ttttctttgg aaggcatcag gcaaacctgg caatacgtcg
    24541 ttgtcgctgt cgcataaatc tataaaggtg agcacaaacc ttgacgagga tttgcttatg
    24601 tttgttgccc tcccctttct cattttttat gcgtcgttct ctttattact tggcatatac
    24661 gacgcgcgta ccggtctgct acctgaccgg tttacctgtc cattactgtg gggtggtctg
    24721 ctttatcacc agatttgcct gccggagcgt ttaccggatg cgctttgggg cgctatcgcc
    24781 ggctatggcg gattcgcgtt aatttactgg ggctatcgcc tgcgttatca gaaagagggg
    24841 cttggatatg gcgacgtcaa gtaccttgct gccttagggg cgtggcattg ttgggaaaca
    24901 ctgccgttac tggttttcct tgccgctatg ttggcctgtg gcaggtttgg cgtcgcgcta
    24961 ctggtgagag gtaaatcggc attaataaac ccgctacctt ttgggccatg gctggcggtg
    25021 gcgggtttca taacaggttg gaaagttttc tttccagacg gttaatcggt aaccttaatt
    25081 tgtgattgca gataattttg cataccaagt ttggcaatca aatccagctc agtttccagc
    25141 cagtcgatgt ggccttcctc gtcggcaaga atttcaatca tcatatcccg gctgacataa
    25201 tcatgaacgt tatcggcata ggctattgcc tcacgtagat cttttgcgcc ttccagttcg
    25261 agccggagat ccgatcgtag catctcttcg acatcttcac cgatgcccag cttgcccaga
    25321 tcctgtaggt tcggtatgcc ttccagaaat aaaatacgct ctatatactt atcggcgtgt
    25381 ttcatctcat caatggattc atggtactca acatcattaa gccgggtcag cccccagttt
    25441 ttgaacatac gggcatgaag aaaatactga ttaattgcga caagctcatt tcccaatagt
    25501 ttattgagat aatttatgat tttaacatca cctttcattt tatagtccct ccgcttccac
    25561 tctctagagc gtagatgggg ctacagggat gtcaaaaaaa agagtgtgac tcaggcgatc
    25621 tctttaaatt ccggcatttg cgttaactca tcctgcatca cttctcgcgc ggcgcgaata
    25681 cacttaccac attgatttcc cacaggaata aatttacgca actgttgaaa tgactgtgga
    25741 tgaaattgtc gtacagcctg gcggattttt ttatcgctta taccattaca caaacaaacg
    25801 tacatgatcg ctcccgttca atttccgcac aaagtgtaaa tgagaatggt tatgattaca
    25861 atagcacaaa gcgatttacg ccacgggaga agcgttaaaa aaggcaaata aatataacag
    25921 cggctaaata gcaggcaaca aaaagggcgc cgaagcgccc tcttcaattc aaaactaatt
    25981 aacgagtaat tagcccagaa ctttagcaac aacgcccgcg ccaacggtac ggccgccttc
    26041 acggattgcg aaacgcagac cgtcgtccat tgcgatcggg tggatcaggg taacaaccat
    26101 tttgatgttg tcgcccggca ttaccatctc tacgccttcc ggcagttcga tggtgccagt
    26161 cacgtcagta gtacggaagt agaactgcgg acggtagcct ttgaagaacg gagtatgacg
    26221 gccgccttca tctttggaca gaatgtacac ttcagattcg aacttggtgt gtggcttgat
    26281 ggtgcccggc ttagccagta cctgaccacg ttcgatttct tcacgtttga taccacgcag
    26341 cagaacacct acgttctcac c
//
LOCUS       DAJVBX010000038        26151 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.038, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000038 DAJVBX010000000
VERSION     DAJVBX010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 26151)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26151)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26151
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.038"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            235..1365
                     /locus_tag="OPV72_001423"
     CDS             235..1365
                     /locus_tag="OPV72_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HCR9913776.1"
                     /translation="MGQDSDDRRRTSSAGRVWQDHKDMVRQALRVSIPWFTFVNISFA
                     LIILFRHILISDFDKSISAQTGILPLIDDIMGSIIVFSFLILLFIYRLPARFTPLCLV
                     MLLILSLMWSYCSYCFIVWWQLPFAWPLSVILMLTALAALYYHLPALLLFIVPLWLTA
                     LLASVQLNQYVNIRFLLVWLTLTAILIYGRFILQRWFDEAWLRYQENRMLIARLDVMA
                     HQDALTGTANRRSMESFLGDALRQTEPFALIMLDVDYFKNYNDNYGHQAGDACLAKVA
                     CVVKRSIRTPADLVARYGGEEFVVVLPSSSLNEAALVAKRIQTNLRETALPHVASAVS
                     ETVTVSMGITLSTAGDTVTGIIARADEALYRAKQQGRNRWVK"
     gene            complement(1651..2046)
                     /locus_tag="OPV72_001424"
                     /pseudo
     CDS             complement(1651..2046)
                     /locus_tag="OPV72_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089414.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF977 family protein"
     gene            2170..2531
                     /locus_tag="OPV72_001425"
                     /pseudo
     CDS             2170..2531
                     /locus_tag="OPV72_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415865.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
     gene            2533..2838
                     /locus_tag="OPV72_001426"
                     /pseudo
     CDS             2533..2838
                     /locus_tag="OPV72_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001189081.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(3202..3555)
                     /locus_tag="OPV72_001427"
     CDS             complement(3202..3555)
                     /locus_tag="OPV72_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebY family protein"
                     /protein_id="HCR9913777.1"
                     /translation="MKKILLPALLLATSGVALAAPQVITVSRFEVGKDKWAFNREEVM
                     LTCRPGQALYVINPSTLVQYPLNAIAEQQVAEGKTRAQPIAIIQIDNPAKPGEKMSLA
                     PFIERAQKLCDPSNS"
     gene            complement(3572..4447)
                     /gene="copD"
                     /locus_tag="OPV72_001428"
     CDS             complement(3572..4447)
                     /gene="copD"
                     /locus_tag="OPV72_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis membrane protein CopD"
                     /protein_id="HCR9913778.1"
                     /translation="MMLTFVWITLRFIHFASLMLVYGCALYGAWLAPASIRRLMTRRF
                     LHLQRHAAAWSVISAAFMLAIQGGLMGGGWPDVFSVSVWGAVLQTRFGAVWIWQIILA
                     LVTLAVVVIAPVKMQRRLLILTVAQFILLAGVGHATMRDGVAGTLQQINHALHLLCAA
                     AWFGGLLPVVYCMRMAQGRWRQHAISAMMSFSRYGHFFVAGVLLTGIGNTLFITGFTA
                     IWQTTYGQLLLLKCALVVLMVAIALTNRYVLVPRMRQENPRTDLWFVRMTQIEWGVGG
                     IVLAIVSLFATLEPF"
     gene            complement(4448..4822)
                     /gene="yobA"
                     /locus_tag="OPV72_001429"
     CDS             complement(4448..4822)
                     /gene="yobA"
                     /locus_tag="OPV72_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopC domain-containing protein YobA"
                     /protein_id="HCR9913779.1"
                     /translation="MASSAPSRRLALLLLASTFATPAAWAHAHLTHQYPAANAAVTAS
                     PQALTLNFFEGIEPGFSGATITGPQQESIKTRPAKRNEQDKTQLIIPLEQPLKSGAYT
                     VDWHVVSVDGHKTKGKYTFSVK"
     gene            4960..5190
                     /locus_tag="OPV72_001430"
     CDS             4960..5190
                     /locus_tag="OPV72_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit theta"
                     /protein_id="HCR9913780.1"
                     /translation="MKTNLAQLEQAEMDKVNVDLAAAGVAFKERYNMPVVAEAVEREQ
                     PEHLRAWFRERLIAHRLASVSLSRLPYEPKVK"
     gene            5298..5954
                     /locus_tag="OPV72_001431"
     CDS             5298..5954
                     /locus_tag="OPV72_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HCR9913781.1"
                     /translation="MSSWKIAAAQYAPLNASPAEHVAHHLEYIELAARQQCELLVFPS
                     LSLLGCDERNKPLPAPPDEALLQPLTHAADTHHMTIIVGMPVEHNCRFVKGIAIFAPW
                     LTSPLMFHKSHGACIARQRSAINVVDEQPEGGDIGPSFTLFTTSQCLNEPELHASTSR
                     LQRFSHKYALAVLMANACGSSALWDESGQLIVRADCGSLLLTGLRTTEGWQGDIIPLR
                     "
     gene            5978..6676
                     /gene="exoX"
                     /locus_tag="OPV72_001432"
     CDS             5978..6676
                     /gene="exoX"
                     /locus_tag="OPV72_001432"
                     /EC_number="3.1.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease X"
                     /protein_id="HCR9913782.1"
                     /translation="MLRIIDTETCGLQGGIVEIASVDVIDGNIVNPMSHLIRPDRPIT
                     PQAMAIHRITEAMVADKPWIEDVIPLYYGSEWYVAHNASFDRRVLPELPGEWICTMKL
                     SRRLWPGIKYSNMALYKSRKLSVQTPPGLHHHRALYDCYITAALLIDIMRTTGWTAEE
                     MVNITGRPALLTTFPFGKYRGKAVSEVAKRDPGYLRWLFNNLDNMSPELRLTLKHYLE
                     DVQAGEQRSNGTPQ"
     gene            complement(6713..8764)
                     /gene="ptrB"
                     /locus_tag="OPV72_001433"
     CDS             complement(6713..8764)
                     /gene="ptrB"
                     /locus_tag="OPV72_001433"
                     /EC_number="3.4.21.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptidase B"
                     /protein_id="HCR9913783.1"
                     /translation="MLPKANRIPYAMTVHGDTRIDNYYWLRDDTRSQPEVLDYLHQEN
                     EYGRKVMSSQQALQDRILKEIIDRIPPREVSAPYVKNGYRYRYIYEPGCEYAIYQRQS
                     ALSEEWNVWETLLDANQRAAHSEFYTLGGLAITPDNTIMALAEDYLSRRQYGLRFRNL
                     ESGNWYPELLDNVAPEFVWANDSLTLYYVRKHKKTLLPYQVWRHTIGTPSSQDELVYE
                     EKDDTFYVSLHKTTSQHYVVIHLASATTSEVLLLDAELADAEPFSFLPRRKDHEYSLD
                     HYQHKFYLRSNRNGKNFGLYRTRVRNENAWEELIPPREHIMLEGFTLFTDWLVVEERQ
                     RGLTSLRQINRKTREVIGIAFDDPAYVTWLAYNPEPETSRLRYGYSSMTTPDTLFELD
                     MDTGERRVLKQTEVPGFDSGCYQSEHLWITARDGVEVPVSLVYHQKYFRKGQNPLLVY
                     GYGSYGSSIDADFSSSRLSLLDRGFVYAIVHVRGGGELGQQWYEDGKFLKKRNTFNDY
                     LDACDALLKLGYGSPSLCYGMGGSAGGMLMGVAINERPELFHGVIAQVPFVDVLTTML
                     DESIPLTTGEFEEWGNPQDIEYYDYMKSYSPYDNVKAQDYPHLLVTTGLHDSQVQYWE
                     PAKWVAKLRELKTDQRLLLLCTDMDSGHGGKSGRFKSYEGVALEFAFLIGLAQGTLHS
                     A"
     gene            complement(8978..9637)
                     /locus_tag="OPV72_001434"
     CDS             complement(8978..9637)
                     /locus_tag="OPV72_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tellurite resistance TerB family protein"
                     /protein_id="HCR9913784.1"
                     /translation="MANWLNQLQSLLGQKGASASPSGEQGLNKLLVPGALGGLAGLLV
                     ANKSSRKLLTKYGTGALLVGGGAVASSVLWNKYKDKVRAAHQGEPQFGSQSTPLDIRT
                     ERLILALVFAAKSDGHIDAKERAAIEHQLRESGVEEQGRVFIEKAIEQPLDPQRLAQG
                     VRNEEEALEIYFLSCAAIDIDHFMERSYLNALGDALKIPQEVRDGIEQDLQQQKQALP
                     G"
     gene            complement(9731..10084)
                     /locus_tag="OPV72_001435"
     CDS             complement(9731..10084)
                     /locus_tag="OPV72_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913785.1"
                     /translation="MNKRGALLSLLLLSASVSAFAASTESKSVKFPQCEGLDAAGIAA
                     SVKRDYQQNRIVRWADDQKKVGQADPVAWVNVQDVVGQNDKWTVPLTVRGKSADIHYQ
                     VIVDCKAGKAEYKPR"
     gene            complement(10152..10442)
                     /gene="yebG"
                     /locus_tag="OPV72_001436"
     CDS             complement(10152..10442)
                     /gene="yebG"
                     /locus_tag="OPV72_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA damage-inducible protein YebG"
                     /protein_id="HCR9913786.1"
                     /translation="MAVEVKYVVIREGEEKMSFTSKKEADAWDKMLDTADLLDTWLEQ
                     SPVVLEDGQREALSLWMAEHKEVLSTILKTGKLPSPQAVEKDAASKTKKQAA"
     gene            10573..11751
                     /gene="purT"
                     /locus_tag="OPV72_001437"
     CDS             10573..11751
                     /gene="purT"
                     /locus_tag="OPV72_001437"
                     /EC_number="2.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate-dependent phosphoribosylglycinamide
                     formyltransferase"
                     /protein_id="HCR9913787.1"
                     /translation="MTLLGTALRPAATRVMLLGAGELGKEVAIECQRLGIEVIAVDRY
                     PDAPAMHVAHRSHVINMLDGEALRHVITEEKPHYIVPEIEAIATDTLRELEGEGLNVV
                     PCARATQLTMNREGIRRLAAEELGLPTSTYRFADSEASFHDAVAAVGFPCIVKPVMSS
                     SGKGQSFIRSAEQLAQAWEYAQQGGRAGAGRVIVEGVVKFDFEITLLTVSAVDGVHFC
                     APVGHRQQDGDYRESWQPQQMSELALKRAQEIARHVVLALGGHGLFGVELFVCGDEVI
                     FSEVSPRPHDTGMVTLISQDLSEFALHVRAFLGMPIGAIRQYGPAASAVILPQLTSQN
                     VTFDDVHAAVGAGVQVRLFGKPEIDGTRRLGVALATGENVEEAVIRAKKAASRVTVKG
                     "
     gene            complement(11851..12492)
                     /gene="kdgA"
                     /locus_tag="OPV72_001438"
                     /gene_synonym="eda"
     CDS             complement(11851..12492)
                     /gene="kdgA"
                     /locus_tag="OPV72_001438"
                     /gene_synonym="eda"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HCR9913788.1"
                     /translation="MKNWKTSAEAILTTGPVVPVIVVNKLEHAVPMAKALVAGGVRVL
                     EVTLRTACAMDAIRAIAKDVPEAIVGAGTVLNPQQLAEVTEAGAQFAISPGLTEPLLK
                     AATAGTIPLIPGISTVSELMLGMDYGLKEFKFFPAEANGGTKALQAIAGPFSQVRFCP
                     TGGISLANYRDYLALKSVLCIGGSWLVPADALEAGDYDRITKLAREAVEGAKQ"
     gene            complement(12530..14341)
                     /gene="edd"
                     /locus_tag="OPV72_001439"
     CDS             complement(12530..14341)
                     /gene="edd"
                     /locus_tag="OPV72_001439"
                     /EC_number="4.2.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphogluconate dehydratase"
                     /protein_id="HCR9913789.1"
                     /translation="MNPNLLRVTQRIVERSQQTRKAYLARIEQAKTATVHRSQLACGN
                     LAHGFAACQPEDKASLKSMLRNNIAIITSYNDMLSAHQPYEHYPQIIRQALHSVNAVG
                     QVAGGVPAMCDGVTQGQDGMELSLLSREVIAMSAAVGLSHNMFDGALFLGVCDKIVPG
                     LAMAALSFGHLPAIFVPSGPMASGLPNKEKVRIRQLYAEGKVDRMALLESEAASYHAP
                     GTCTFYGTANTNQMVVEFMGMQLPGSSFVHPDAPLREALTAAAARQVTRLTGNGNTWM
                     PLGKMIDEKVVVNGIVALLATGGSTNHTMHLVAMARAAGILINWDDFSDLSEVVPLMA
                     RLYPNGPADINHFQAAGGVPVLMRELLNAGLLHEDVNTVAGFGLKRYTLEPWLNNGEL
                     DWREGAERSLDNDVIASFDKPFSPHGGTKVLSGNLGRAVMKTSAVPVENQIIEAPAMV
                     FESQHDVLPAFDAGLLDRDCVVVVRHQGPKANGMPELHKLMPPLGVLLDRRFKIALVT
                     DGRLSGASGKVPSAIHVTPEAYDGGLLAKVRDGDIIRVNGQTGELTLLVDEAELAARQ
                     PHIPDLSASRVGTGRELFGALREKLSGAEQGATCITF"
     gene            complement(14576..16051)
                     /gene="zwf"
                     /locus_tag="OPV72_001440"
     CDS             complement(14576..16051)
                     /gene="zwf"
                     /locus_tag="OPV72_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HCR9913790.1"
                     /translation="MAVTQTAQACDLVIFGAKGDLARRKLLPSLYQLEKAGQIHPDTR
                     IIGVGRADWDKEAYTHVVREALETFMKEKIDEGLWDTLSGRLDFCNLDVNDTPAFSRL
                     GDMLDQKNRTTINYFAMPPSTFGAICKGLGEAKLNAKPARVVMEKPLGTSLATSREIN
                     DRVGEYFEECQVYRIDHYLGKETVLNLLALRFANSLFVNNWDNRTIDHVEITVAEEVG
                     IEGRWGYFDQAGQMRDMIQNHLLQILCMIAMSPPSDLSADSIRDEKVKVLKSLRRIDR
                     SNVREKTVRGQYTAGFAQGQKVPGYLEEEGANKSSNTETFVAIRVDIDNWRWAGVPFY
                     LRTGKRLPTKCSEVVVYFKTPELNLFKESWQDLPQNKLTIRLQPDEGVDIQVLNKVPR
                     LDHKHNLQITKLDLSYSETFNQTHLADAYERLLLETMRGIQALFVRRDEVEEAWKWVD
                     SITEAWAMDNDAPKPYQAGTWGPVASVAMITRDGRSWNEFE"
     gene            16393..17262
                     /locus_tag="OPV72_001441"
     CDS             16393..17262
                     /locus_tag="OPV72_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCR9913791.1"
                     /translation="MNMLEKVQSQLEHLSKSERKVADVILAAPGRSIHLSIAMLAQEA
                     NVSEPTVNRFCRSMNTRGFPDFKLHLAQSLANGTPYVNRNVDEDDSVEAYTGKIFESA
                     MASLDHVRQSLDKSAVNRAVDLLTQAKKIAFFGLGSSAAVAHDAMNKFFRFNVPVIYS
                     DDIVLQRMSCMNCNDDDVVVLISHTGRTKSLVELAQLARENDAMVIALTSAGTPLARE
                     ATLAITLDVPEDTDIYMPMVSRLAQLTVIDVLATGFTLRRGAKFRDNLKRVKEALKES
                     RFDKELLIRSDDR"
     gene            17386..18828
                     /gene="pyk"
                     /locus_tag="OPV72_001442"
     CDS             17386..18828
                     /gene="pyk"
                     /locus_tag="OPV72_001442"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HCR9913792.1"
                     /translation="MSRRLRRTKIVTTLGPATDRDNNLEKVIAAGANVVRMNFSHGSP
                     EDHKMRADKVREIAAKLGRHVAILGDLQGPKIRVSTFKEGKVFLNIGDKFLLDANLGK
                     GEGDKEKVGIDYKGLPADVVPGDILLLDDGRVQLKVLEVQGMKVFTEVTVGGPLSNNK
                     GINKLGGGLSAEALTEKDKADIQTAALIGVDYLAVSFPRCGEDLNYARRLARDAGCDA
                     KIVAKVERAEAVCDQNAMDDIILASDVVMVARGNLGVEIGDPELVGIQKALIRRARQL
                     NRAVITATQMMESMITNPMPTRAEVMDVANAVLDGTDAVMLSAETAAGQYPSETVAAM
                     ARVCLGAEKIPSINVSKHRLDVQFDNVEEAIAMSAMYAANHLKGVTAIITMTESGRTA
                     LMTSRISSGLPIFAMSRHERTLNLTALYRGVTPVHFDSAADGVVAAHEAVNLLRDKGY
                     LVSGDLVIVTQGDVMSTVGSTNTTRILTVE"
     gene            complement(18901..19872)
                     /gene="lpxM"
                     /locus_tag="OPV72_001443"
                     /gene_synonym="msbB"
     CDS             complement(18901..19872)
                     /gene="lpxM"
                     /locus_tag="OPV72_001443"
                     /gene_synonym="msbB"
                     /EC_number="2.3.1.243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460846.1"
                     /note="LpxM is lauroyl-Kdo(2)-lipid IV(A)
                     myristoyltransferase, an enzyme characterized in
                     Escherichia coli and involved in biosynthesis of the form
                     of lipid A found in that species and some closely related
                     species; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lauroyl-Kdo(2)-lipid IV(A) myristoyltransferase"
                     /protein_id="HCR9913793.1"
                     /translation="METKKNNSEYIPEFEKSFRYPQYWGAWLGAAAMAGIALTPASFR
                     DPLLATLGRFAGRLGKSSRRRALINLSLCFPQRSEAEREAIVDEMFATAPQAMAMMAE
                     LAMRGPKKIQQRVDWEGLEIIEEMRRNDEKVIFLVPHGWGVDIPAMLMASQGQKMAAM
                     FHNQGNPVFDYIWNTVRRRFGGRLHARNDGIKPFIQSVRQGYWGYYLPDQDHGPEHSE
                     FVDFFATYKATLPAIGRLMKVCRARVIPLFPVYNGKTHRLTIQIRPPMDDLLTADDHT
                     IARRMNEEVEIFVGPHPEQYTWILKLLKTRKPGEIQPYKRKDLYPIK"
     gene            complement(19989..21308)
                     /gene="mepM"
                     /locus_tag="OPV72_001444"
     CDS             complement(19989..21308)
                     /gene="mepM"
                     /locus_tag="OPV72_001444"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein DD-endopeptidase MepM"
                     /protein_id="HCR9913794.1"
                     /translation="MQQIAGSVALAFNNLPRPHRVMLGSLTVLTLAVAVWRPYVYHPE
                     SAPIVKTIELEKSEIRSLLPEASEPIDQAAQEDEAIPQDELDDKTAGEVGVHEYVVST
                     GDTLSSILNQYGIDMSDISRLAASDKELRNLKIGQQLSWTLTADGDLQRLTWEVSRRE
                     TRTYDRTANGFKMSSEMQQGDWVNSLLKGTVGGSFVASAKEAGLTSSEISAVIKAMQW
                     QMDFRKLKKGDEFSVLMSREMLDGKREQSQLLGVRMRSDGKDYYAIRAADGKFYDRNG
                     VGLAKGFLRFPTAKQFRISSNFNPRRLNPVTGRVAPHRGVDFAMPQGTPVLSVGDGEV
                     VVAKRSGAAGYYIAIRHGRTYTTRYMHLRKLLVKPGQKVKRGDRIALSGNTGRSTGPH
                     LHYEVWINQQAVNPLTAKLPRTEGLTGSDRREYLAQVKEILPQLRFD"
     gene            complement(21324..22268)
                     /gene="znuA"
                     /locus_tag="OPV72_001445"
     CDS             complement(21324..22268)
                     /gene="znuA"
                     /locus_tag="OPV72_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416371.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     ZnuA"
                     /protein_id="HCR9913795.1"
                     /translation="MLQKNTLLFAALSAALWGSATQAADAAVVASLKPLGFIASAIAD
                     GVTDTQVLLPDGASEHDYSLRPSDVKRLQGADLVVWVGPEMEAFMEKSVRNIPDNKQV
                     TIAQLADVKPLLMKGADDDEDEHAHTGADEEKGDVHHHHGEYNMHLWLSPEIARATAV
                     AIHEKLVELMPQSRAKLDANLKDFEAQLAATDKQVGNELAPLKGKGYFVFHDAYGYYE
                     KHYGLTPLGHFTVNPEIQPGAQRLHEIRTQLVEQKATCVFAEPQFRPAVVEAVARGTS
                     VRMGTLDPLGTNIKLGKTSYSAFLSQLANQYASCLKGD"
     gene            22347..23102
                     /gene="znuC"
                     /locus_tag="OPV72_001446"
     CDS             22347..23102
                     /gene="znuC"
                     /locus_tag="OPV72_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter ATP-binding protein ZnuC"
                     /protein_id="HCR9913796.1"
                     /translation="MTSLVSLENVSVSFGQRRVLSDVSLELSPGKILTLLGPNGAGKS
                     TLVRVVLGLVAPDEGVIKRNGQLRIGYVPQKLYLDTTLPLTVNRFLRLRPCTQKTDIL
                     PALKRVQAGHLIDAPMQKLSGGETQRVLLARALLNRPQLLVLDEPTQGVDVNGQVALY
                     DLIDQLRRELDCAVLMVSHDLHLVMAKTDEVLCLNHHICCSGAPEVVSMHPEFISMFG
                     PRGAEQLGIYRHHHNHRHDLQGRIVLRRGNGHS"
     gene            23099..23884
                     /gene="znuB"
                     /locus_tag="OPV72_001447"
     CDS             23099..23884
                     /gene="znuB"
                     /locus_tag="OPV72_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter permease subunit ZnuB"
                     /protein_id="HCR9913797.1"
                     /translation="MIELLLPGWLAGMMLACAAGPLGSFVVWRRMSYFGDTLAHASLL
                     GVAFGLLLDVNPFYAVIAVTLLLASGLVWLEKRPHLAIDTLLGIMAHSALSLGLVVVS
                     LMSNVRVDLMAYLFGDLLAVTPEDLISIAIGVVIVLAILFWQWRNLLSMTISPDLAFV
                     DGVKLQRVKLLLMLVTALTIGVTMKFVGALIITSLLIIPAATARRFARTPEQMAGVAV
                     GVGMIAVTGGLTFSAFYDTPAGPSVVLCAALLFIFSMMKKQAS"
     gene            complement(23963..24973)
                     /gene="ruvB"
                     /locus_tag="OPV72_001448"
     CDS             complement(23963..24973)
                     /gene="ruvB"
                     /locus_tag="OPV72_001448"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HCR9913798.1"
                     /translation="MIEADRLISAGATIAEDVADRAIRPKLLAEYVGQPQVRSQMEIF
                     IQAAKRRGDALDHLLIFGPPGLGKTTLANIVANEMGVNLRTTSGPVLEKAGDLAAMLT
                     NLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGA
                     TTRAGSLTSPLRDRFGIVQRLEFYQVPDLQHIVGRSARHMGLEMSDDGALEVARRARG
                     TPRIANRLLRRVRDFAEVKHDGAISAEIAAQALDMLNVDAEGFDYMDRKLLLAVIDKF
                     FGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFLQRTPRGRMATVRAWNHFGITPPE
                     MP"
     gene            complement(24982..25593)
                     /gene="ruvA"
                     /locus_tag="OPV72_001449"
     CDS             complement(24982..25593)
                     /gene="ruvA"
                     /locus_tag="OPV72_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012131997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HCR9913799.1"
                     /translation="MIGRLRGIILEKQPPIVLLETGGVGYEVHMPMTCFYELPEAGQE
                     AIVFTHFVVREDAQLLYGFNNKQERTLFKELIKTNGVGPKLALAILSGMSAQQFVNAV
                     EREELGALVKLPGIGKKTAERLIVEMKDRFKGLHGDLFTPAVDLVLTSPASPTSEDAE
                     QEAVAALVALGYKPQEASRMVSKIARPDASSETLIRDALRAAL"
     gene            complement(25953..>26151)
                     /locus_tag="OPV72_001450"
     CDS             complement(25953..>26151)
                     /locus_tag="OPV72_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913800.1"
                     /translation="AAKGRGLAAKRQALFSSEEYVNIYYSYSEGIPAVNFDGMKNEFA
                     QYLLCHGELKYVVRDDKTTCD"
BASE COUNT         6153 a         7082 c         6550 g         6366 t
ORIGIN      
        1 tctgccagtt acatcctctt ttagtaagtg gggtaaactc gcttccagtt tccgggaaac
       61 actataattc tcccccctac tacaggaatt gtgactataa gttcgtcact gtggagcaaa
      121 aatcatctca tcagccaaaa atgcagcctg gcctgatagc ttttccattt ttcaccatga
      181 agtatctccg cactacactg gatagtaatt attcattata tgaggcgatt aaggatgggg
      241 caggattcgg acgacaggcg ccgtacctcc agtgctggaa gggtatggca ggatcataaa
      301 gatatggtca ggcaagcgct acgtgtaagt attccgtggt tcacatttgt gaatatcagc
      361 tttgcgctta tcattttatt tcgccacata ctcatcagtg actttgacaa gtcgatcagt
      421 gcacagactg gaatactgcc tttaatagac gatattatgg gcagtattat tgttttttcg
      481 ttcctgatac tccttttcat ttaccgcctt ccggccagat ttactcctct ttgtctggtg
      541 atgctgctga ttctcagtct gatgtggagc tattgtagct actgttttat tgtctggtgg
      601 caactgcctt ttgcctggcc tctcagtgtc atccttatgc ttaccgcgct ggctgcgctt
      661 tattatcatc tgccagcgtt gctacttttc atcgtcccgt tatggctgac cgccctactg
      721 gccagcgtgc agcttaacca gtatgtgaat atccggtttt tattagtctg gcttactctt
      781 accgccatac tcatttatgg tcgctttatc ctgcagcgct ggtttgatga agcctggttg
      841 cgttaccagg aaaaccggat gcttatcgcg cgtctcgacg ttatggctca ccaggatgca
      901 ctgaccggga ccgctaatcg acgttcaatg gaaagttttc ttggggatgc tctccgccag
      961 acggagccgt ttgcactgat catgctcgat gtggactatt tcaaaaacta taacgacaat
     1021 tatggtcacc aggctggcga tgcctgtctg gcaaaggtgg cctgtgtagt aaagaggtcg
     1081 attcgtactc cggcagacct ggtggcacgt tacgggggcg aggagtttgt cgttgtgctg
     1141 ccttcgtcgt cgctgaatga agctgcactg gttgctaaac gtattcagac aaacctgcgt
     1201 gaaaccgcac tgccgcatgt agcatctgcg gtaagcgaaa cggtcaccgt cagcatgggc
     1261 atcacccttt ccacagccgg tgacactgtt accggcatta ttgccagagc ggatgaggcc
     1321 ctttatcggg ctaaacaaca gggacgtaat cgttgggtaa agtaaaacca gttgcccggt
     1381 gtttgataca gaagatcacc ttgccatact cagataatta aaactgaata tttggaagca
     1441 aaaaagacag tcggactcac ggaacctttg cgctggtaca gcctgaatat cagataaaat
     1501 tatgtccagc cgcagacacc agttgacagt ggaatattcc tggtgttgtg aacaaggcga
     1561 cattcacaac acgactgtgc tcacggaatt caaatgccaa acggatgatt acgatattcg
     1621 ctacctctgc aaagttatat tattcgattt tcatgcagat ttcgcctccc ggtaatttcc
     1681 ccgataaaat gccagtaccc tttgcatcgt cacgctgttc cggcactccg tacagataac
     1741 gtttctggtc cggtcgtagg aactcacgac accttccggc gttttcagaa agcgggtaat
     1801 cctggcatct tcacgtttct acttccaaag caggaaagcc tgttccgaag gaaaaatacc
     1861 gcttctcccg gcctgataca gatccccaca actttccgcc ttttccaggt agtgacgggc
     1921 tgtaaaaatg gttaaccctg ttatcttccg aagttctcca aacgtcatcc gaccgtgtgt
     1981 tcgtaccagt tccgtcaggc gcttttgtat ttcagctttc tgcgccggtg tgtaatttct
     2041 gctcataagt ccccccagtt aaagccttcc cgccgcctta cgccgtctga atttttccat
     2101 catcagttgt gccggggttg gccctgccgg atgacgcggc gctgcaagtt gacggcgtac
     2161 cggcggtatg ccacaacgga aatccgaaaa gttccggcgc tgggtgactg tgacaccatg
     2221 agttttgtca gcgccatcgt tcagtgttcc cagcttgggc tggaacccgg cggcgcgctc
     2281 ggtcatgcct atctgctgcc gttcggaaac aaaaacgaaa agtcaggcaa aaaaacgttc
     2341 agttaattat tggctaccgg ggaatgatcg accttgcccg ccgttccgga cagattgcca
     2401 gcctttccgc gcgcgttgtc cgtgaaggtg acgatttcag cttcgagttt ggtctggaag
     2461 agaagctggt acaccgtccg ggtgagaacg aagatgcaca ggttactcat gtctatgccg
     2521 ttgcccgcct taatcgatcg ctgccgactg gtaagccgaa ctgatttcat gatcagtgcc
     2581 ggaatcagga aaaatagccc aaccgggaat attcacccgg atgggctgac aaagaaattt
     2641 gtaaaagcca gaaaaatttc aggcgttaaa tgtagtgata acccaccgac atttcacaag
     2701 atccgtagcc tggctggtcg gctgtacaaa aacgaacgcg gcgaggaatt cgctcaaaaa
     2761 ctactgggcc acacctcaga gaacaccacg aaactctatc tcgatgaacg cgataataaa
     2821 gcttacgtga tgctctgatt ttgttgtaaa agaaatgtta aactgaattt gattgtgata
     2881 taaccaaaaa gaccggaata cagaaattcg aggaaatttc gagggaaaac acataacccg
     2941 ttgatttata atcgaaataa aaagagaccg aatacgattc ctgtattcgg tccagggaaa
     3001 tggctcttgg gagagagccg tgcgctaaaa gttggcatta atgcaggcta aatcgccttg
     3061 ctctttaaga atagatgacg acgccaggtt ttccagtttg tgacgaaggt gattgaaaaa
     3121 acctggcgta ttgtctgtca tcagagataa aaaaaccgta agccttttcg tgaaggttta
     3181 cggtttttta ttaaaaatca gtcagctatt ggatggatca caaagctttt gcgcacgttc
     3241 gataaacggc gccagactca ttttctcacc gggctttgcc gggttatcga tttgaatgat
     3301 ggcaataggc tgagcgcgcg ttttaccctc cgctacttgc tgctcggcaa tagcattcaa
     3361 gggatactgc accagagtac tggggttgat cacatagagc gcctggccag gccgacaggt
     3421 caacatgacc tcttcccgat taaacgccca cttgtctttt cctacttcaa aacgacttac
     3481 ggtaatcacc tgcggcgccg ccaacgctac gcccgaagtg gccagcagaa gcgccggaag
     3541 gagtattttt ttcattcgtt atgccagtcc atcagaaagg ttcgagggtt gcaaacaggc
     3601 tgacgatcgc cagaactatg cctccaactc cccattcaat ttgcgtcatc ctgacaaacc
     3661 ataggtcagt ccggggattt tcctgtcgca tacgtggtac gagaacatac cgattcgtca
     3721 gcgcaattgc taccataagc accaccagcg cacattttaa caaaagcaac tgtccataag
     3781 tggtctgcca gatagcggta aatcccgtga taaatagcgt gttgccaatg cctgtgagca
     3841 atacgcccgc cacaaaaaag tgaccataac gagaaaaact catcatggcg ctaatggcat
     3901 gttgacgcca gcgtccttga gccatgcgca tacaataaac cactggcaac agcccgccaa
     3961 accaggctgc ggcacagagc aaatgcagag catggttaat ttgctgtaat gttcccgcta
     4021 caccatcgcg catcgtcgca tgtccaacgc ctgccagcag gataaactga gcaacggtta
     4081 gaataagaag ccgtcgttgc atttttaccg gcgcaatgac taccaccgcc agcgtgacca
     4141 gcgcgaggat aatttgccat atccagaccg cgccaaagcg ggtttgcagt accgcgcccc
     4201 aaaccgagac ggaaaaaaca tcgggccagc cgccgcccat cagtccgccc tgaattgcca
     4261 gcataaaagc cgcgctgata acgctccagg cggcggcatg tcgttgcaga tgtaaaaatc
     4321 gacgcgtcat taaacgacga attgatgcgg gtgccagcca ggcgccgtaa agcgcgcagc
     4381 cgtagaccag catcaaacta gcaaaatgaa taaatcggag agttatccag acgaatgtca
     4441 gcatcattta tttcacgctg aaggtgtatt tcccttttgt tttatgtcca tccaccgaca
     4501 caacgtgcca gtctaccgtg taagcgccag attttaacgg ctgctcaagc gggataatca
     4561 actgcgtttt atcctgttca tttcgctttg ccgggcgcgt tttgatggac tcttgctgag
     4621 ggccagtaat ggttgcgccg ctgaatcctg gctcaatccc ttcaaaaaag ttcagagtca
     4681 gcgcctgtgg cgaggccgta acggcagcat tcgctgctgg atactgatgc gtcaggtgcg
     4741 catgtgccca ggccgctggc gtcgcaaatg tcgatgccag cagcagtaaa gctaaacgtc
     4801 gcgatggtgc agaagaagcc atattcacta ttcctttttg ttatacctac gttacaaaga
     4861 ataaccttca acaatcaatg agtcgaggat catcatttcc atcttgccat tgccgcggac
     4921 tcttagtacc ttctggcggc aacaaaaaag gagacacgta tgaaaacgaa tctggctcag
     4981 cttgaacaag cggaaatgga taaagtcaat gtggatctgg cggcagctgg ggtggcattt
     5041 aaagagcgct acaatatgcc agttgtcgcg gaggcggtcg aacgtgagca gccagagcat
     5101 ctacgcgcct ggtttcgcga gcggctgatt gcccatcgtc tggcttccgt atcactatcc
     5161 cgactccctt acgaacccaa agttaaataa aaattatata acgttacact tccttacatg
     5221 cagacgacta cattataagg cgattcttaa cctatgcttt ttagaatggc tgtagagact
     5281 atgaaaagga agtcattatg tcctcctgga aaattgccgc tgcgcagtac gcgcccctga
     5341 acgcttcgcc ggcagagcat gtcgcccatc atctggaata tattgagctt gcggctcgtc
     5401 aacagtgcga actgctggtc tttccgtcac tgtcgctatt aggctgcgac gaaagaaata
     5461 aaccgttgcc cgccccgcct gacgaggcgc ttttacagcc gctcactcat gcggccgata
     5521 cccaccatat gactatcatt gtgggtatgc ctgttgagca taactgccgc ttcgtaaaag
     5581 gcatcgctat ttttgcccca tggctaacgt cgccgctcat gtttcacaaa agtcatggcg
     5641 cctgtattgc caggcagcga agcgctatca acgtggtgga tgagcagcca gaaggtggtg
     5701 atataggccc ctcatttacg ttattcacaa ccagtcaatg tcttaacgag cctgaactcc
     5761 atgcttctac ctcacgctta caacgttttt cgcataaata tgcgctggcc gtactgatgg
     5821 ccaatgcctg tggcagtagc gcgctgtggg atgaaagcgg gcaacttatt gttcgtgccg
     5881 attgcggttc gctattactg acgggtctgc gcacaaccga gggttggcaa ggcgatatca
     5941 ttccattacg ctaaggtctt tgggtgagga atgaatcatg ttgcggatta tagacacgga
     6001 aacctgcggg ctgcagggcg ggatcgtaga gatagcctct gtagatgtca ttgatggcaa
     6061 cattgtcaat cccatgagtc acctgatacg ccccgatcgc cctattacgc cgcaggcgat
     6121 ggcgatacac cgtattaccg aagccatggt cgccgataag ccgtggattg aagatgtcat
     6181 accgctttat tacggtagtg agtggtatgt cgctcacaat gccagtttcg acagacgcgt
     6241 attacctgaa ttgccgggtg agtggatctg taccatgaag ttgtcgcgac gcctgtggcc
     6301 gggaataaaa tacagcaata tggcgctcta taaatcgcgc aaactaagcg tacaaacgcc
     6361 gccggggctg caccatcacc gggcgcttta tgattgctat atcaccgccg ccttgctgat
     6421 tgatattatg cgaaccaccg gctggaccgc ggaagagatg gtcaatatca cgggccgtcc
     6481 tgcgctgtta accactttcc cgttcggtaa ataccgcggt aaggcggtat ctgaagtcgc
     6541 aaaacgcgat ccgggctatt tacgctggct ttttaataac cttgataata tgagcccgga
     6601 acttcgcctg acgcttaaac actacctgga agatgttcag gctggcgagc aacgcagcaa
     6661 tggaacacca caataacccg cgacgctcac aagccgttgc gggcgcgcgc gtctatgcgc
     6721 tatgtaaggt tccctgcgcc aggccgatta aaaaggcgaa ctccagcgcg acgccttcgt
     6781 aggatttaaa ccgccccgac ttaccaccgt gcccggagtc catatccgta cataacagca
     6841 gcagacgttg gtccgttttt agctcgcgta attttgccac ccacttcgcc ggttcccagt
     6901 attgcacctg ggaatcgtgc aatcctgtcg tcaccagcag gtgcggatag tcctgcgctt
     6961 tgacattgtc ataaggacta tagcttttca tatagtcata atactcaata tcctgcgggt
     7021 tcccccactc ttcaaactcc cctgtcgtta atgggatcga ctcatccagc atcgtggtta
     7081 atacatcaac aaagggcacc tgggcaataa cgccgtggaa aagctcgggg cgttcgttga
     7141 tagcgacgcc cattagcatt ccgcccgcgc tcccgcccat cccataacac agcgacggtg
     7201 aaccgtaacc cagttttaat aaggcatcgc aggcatcaag atagtcatta aaagtattcc
     7261 gctttttgag gaatttgcca tcttcatacc actgctgccc cagctcaccg ccgccgcgaa
     7321 cgtgtacgat tgcgtaaaca aagccacgat ccagcaagct cagtcggctg ctgctgaagt
     7381 cggcgtcaat actggaaccg taagatccgt aaccgtaaac cagaagcgga ttttgccctt
     7441 tacgaaaata cttctgatga taaaccagcg ataccggcac ttcgacgccg tcgcgtgcgg
     7501 tgatccacag gtgttcgctc tgataacagc cagaatcaaa cccaggcact tccgtctgtt
     7561 taagtacccg tcgttctccg gtatccatat ccagttcaaa caaggtatct ggcgtcgtca
     7621 ttgaagaata gccgtaacgc agccgggagg tctcaggttc gggattatag gcaagccacg
     7681 tcacgtaagc cggatcgtca aaggcaatgc ctatcacttc acgggtttta cggttaattt
     7741 gccgcaggct ggtaagcccc cgttgacgct cttcgaccac taaccagtcg gtaaacaggg
     7801 taaacccttc cagcataata tgctcgcgcg gagggatcag ctcttcccag gcgttttcat
     7861 tgcgcacgcg ggtacggtac aacccaaagt ttttaccgtt ccggttagag cgcaggtaaa
     7921 acttatgttg atagtgatcg agactatatt catggtcttt gcggcgcggt aagaatgaaa
     7981 acggctcggc atcggccagt tccgcgtcaa gtaatagcac ttcgctagtg gtggcgctgg
     8041 caagatgaat caccacataa tgctgcgaag tggttttatg caggctgaca taaaaggtat
     8101 cgtctttctc ctcatatacc agttcatctt gcgatgacgg agtgccaatc gtgtgccgcc
     8161 aaacctgata gggcagcagc gtcttcttat gcttacgcac atagtaaaga gtcagggaat
     8221 cattggccca gacaaattca ggcgcaacgt tatccagcag ttccggatac cagttaccgc
     8281 tttcgaggtt acgaaaacgc aacccatact gacgacggga taaataatct tctgccagcg
     8341 ccatgatggt attatccggc gtaatggcaa gcccgccgag cgtataaaat tcgctgtgcg
     8401 cggcccgctg gttcgcatcg agcaaggttt cccacacatt ccactcttcg cttaacgccg
     8461 attgtcgttg atagatggca tattcgcagc cgggttcata gatataacgg tagcgatagc
     8521 cgtttttcac atacggagcg gaaacttctc tgggcgggat gcgatcgata atttctttta
     8581 gaatgcggtc ctgtaacgcc tgctgagagg acatgacctt ccggccatac tcattttcct
     8641 gatgcaggta atcaaggact tccggctgcg agcgagtgtc atctcgcagc cagtaataat
     8701 tatcaatgcg cgtatcgcca tgtacggtca tggcataggg aattcgattg gcttttggca
     8761 acatgtcgtt ttttcttttg cgttaatatt tgttatatat cacgcggcaa acacagcggc
     8821 ttagcatggt agtcccggtc cgctcacctc ggtaagcgcc tgagatgtca ctgcttcgcc
     8881 gctatcttgc aacatgaatg acgtaaacta tccatcctat aagggtggca aaagacacgc
     8941 atgatgcaag cgaaacatgt tacttaatgg caggttatca gcctggtagc gcctgttttt
     9001 gctgctgcaa gtcctgctcg ataccgtccc gaacctcctg aggaattttt agcgcgtctc
     9061 ctaacgcatt cagatagcta cgttccataa agtggtcaat atcaatggcg gcgcagctca
     9121 ggaagtagat ttccagggct tcttcttcat tgcgaacgcc ctgtgccaga cgttgtggat
     9181 caagcggctg ctcaatagct ttctcgataa acacacgccc ttgctcttcc acacctgatt
     9241 ctcgcagttg gtgctcaatc gccgcgcgtt ctttggcatc aatatgccca tcgctttttg
     9301 cagcaaaaac cagcgctagg atcagtcgct cagtgcgaat atccagcggc gtactttggc
     9361 tgccgaattg cggctccccc tgatgcgcag cgcgtacttt atctttgtac ttattccaca
     9421 atacggaact cgccaccgcg ccgccgccca ccagcaaagc gccagtaccg tatttggtta
     9481 ataatttgcg cgaagactta ttggcgacca acagtccagc cagaccgccc agcgcgccgg
     9541 gaaccagcag tttatttaac ccctgttcac cggaaggcga tgcagaagcg cctttttgcc
     9601 caagaagtga ttgtaattgg ttcaaccagt tagccatagt acccctcaaa tacagaccaa
     9661 taatggtcaa gcgtacctga ggggatgtca ggaattgtct gttccggcaa aagaagcgca
     9721 aattacgctg ctagcggggc ttatattccg ccttgccggc tttgcaatca acgatgacct
     9781 gataatggat atcggcgctt ttaccgcgaa cggttagcgg aacggtccat ttatcatttt
     9841 gacccacaac gtcctgcaca ttaacccacg cgaccgggtc agcctgcccg accttttttt
     9901 ggtcgtctgc ccaccgcacg atacgatttt gctggtagtc gcgcttcacg cttgccgcaa
     9961 tcccggcggc atccagccct tcgcactgcg gaaacttaac cgatttactc tcggtggatg
    10021 ccgcaaatgc cgatacgctg gcggataaca acagcaggct caacaacgct cctcttttat
    10081 tcatactttt ctccttagca caatgattca ggaaaagcat ggtacaaaac gccgagagcg
    10141 caagtgtggg ttcaggcggc ttgctttttc gttttactcg cggcgtcctt ttcaaccgcc
    10201 tgcggagaag gcaacttacc ggttttgagg atcgtgctta acacctcttt atgttccgcc
    10261 atccacagcg acaacgcctc gcgctgccca tcttccagca cgactggcga ctgctcaagc
    10321 caggtatcaa gaagatcggc agtatcgagc attttgtccc aggcgtcggc ttccttttta
    10381 ctggtaaatg acatcttctc ctcaccctcg cgaatgacta cgtatttaac ttcaaccgcc
    10441 attttgcagc cccttattta cctgtgttta tatacagtat attgcaaggc ggcaagaaaa
    10501 gcaatttatt cgaaaagaca tacgcaaacg ttttcgtata tactgcgcgc aggtaaataa
    10561 ggggacagaa atatgacgct attaggcact gcgctacgtc cggcagcaac gcgggtgatg
    10621 ttattagggg caggtgaatt gggaaaagag gtggcgattg aatgccaacg cctggggatc
    10681 gaggttatcg ccgtcgatcg ctatcctgat gctcccgcca tgcatgtggc tcaccgttca
    10741 cacgtcatta atatgctgga cggcgaggcg ctacgtcatg tgattacaga ggaaaaaccg
    10801 cattatatcg tgccggaaat agaagcgatc gccaccgata cgctgcgcga gctggagggc
    10861 gaagggctga atgtcgtgcc ttgcgcccgt gcaacgcagc tcacgatgaa ccgcgaaggg
    10921 atccgtcgcc tggccgcaga agaattaggt ctgccgacat cgacgtatcg ctttgccgac
    10981 agtgaggcca gttttcatga tgcggtagcc gcagtgggtt ttccttgcat cgtcaaaccg
    11041 gtcatgagct cttccggcaa aggccagagc tttatccgct cggccgaaca gctcgcgcag
    11101 gcatgggagt atgctcaaca gggcggacgc gctggcgcgg gtcgcgtgat tgtggaaggc
    11161 gtggttaaat ttgattttga aattacgctg ctcaccgtta gcgccgtcga tggcgtgcat
    11221 ttctgcgcgc cggtcggtca tcgtcagcaa gatggtgact atcgcgaatc ctggcaacca
    11281 cagcagatga gcgaactggc gctgaagcgg gcgcaagaga ttgctcgtca tgtggtactg
    11341 gcgttaggcg gtcatggtct gttcggcgtt gaactcttcg tctgtggcga tgaagtcatt
    11401 ttcagcgaag tctcccctcg cccgcacgat accggaatgg tcacgttgat ttctcaggat
    11461 ctttctgagt ttgcgctgca tgtgcgcgcc tttctgggaa tgcccatagg cgctattcgc
    11521 cagtatggtc ccgctgcctc ggccgtgatt ctgccgcagc ttaccagtca aaatgtgacg
    11581 tttgatgatg tacacgcggc ggtaggggcc ggagtgcagg tacggctgtt tggtaagcct
    11641 gagatcgacg gcacccgtcg tcttggtgta gcgttagcga caggtgaaaa cgttgaagaa
    11701 gcggtgataa gagcgaaaaa ggccgccagc cgcgtgacgg taaaaggcta atgcgccatc
    11761 gcctgatggc gacgttagcg catttttatc aggcctgcct gatcgccact cgtaagcccg
    11821 ataagcaagc gccatcgggc atttaacggc ttactgcttc gcgccttcta ccgcttcgcg
    11881 cgccagtttg gtgatgcgat cgtaatcacc cgcttccagc gcgtcggccg gcaccagcca
    11941 ggaaccgccg atgcacaaca cgcttttcag cgccagatag tcacgatagt ttgccagaga
    12001 gatgccgccg gttgggcaga aacgtacctg agagaacgga ccggcaatcg cctgcaacgc
    12061 tttagtgccg ccattcgctt ccgccgggaa gaatttgaac tctttcagac catagtccat
    12121 gcccaacatc agttcagaaa cggtgctaat accgggaatc aatgggatag tgcctgccgt
    12181 cgcggctttc agcagtggct cagtcagtcc cgggctaatc gcaaactgcg cgcccgcctc
    12241 cgtcacctcc gccaactgct gcggattgag aacggttccg gcgccgacaa tcgcttccgg
    12301 cacgtcttta gcgatagcgc gaatagcatc catcgcgcag gccgtacgta aagtcacttc
    12361 cagaacgcga acgcccccgg ccaccagcgc tttagccatc ggcaccgcgt gctccagttt
    12421 attgactaca atgaccggga caaccgggcc ggtggtcagg attgcttctg cacttgtttt
    12481 ccagtttttc atcggaattc ttctctcgcc tgattactag tgtgtcatct taaaaagtga
    12541 tacaggttgc gccctgctcc gcacccgaca gcttttcgcg cagcgcgcca aacaactcac
    12601 gccccgttcc gacgcgcgac gcgctcaggt ccggaatatg aggctgacga gcggcaagtt
    12661 ccgcctcgtc gaccagcaga gttaactcac ctgtctgccc attcacgcga atgatgtcgc
    12721 catcgcgcac ttttgccagt aagccgccat cgtaggcttc cggcgttacg tggatagctg
    12781 aaggcacttt acccgaagcg cctgaaagtc gtccatcagt aactaacgcg attttgaaac
    12841 ggcggtccaa taatacacca agtggcggca tgagtttatg taattctggc attccattcg
    12901 cttttggtcc ctgatgacgc acgacaacga cacaatcccg gtcaagcagg cccgcgtcaa
    12961 acgcaggcag cacatcatgc tgactttcaa ataccatggc aggcgcttca atgatctggt
    13021 tttcaaccgg taccgcagac gtcttcatta ctgcgcgccc cagattaccg cttagcacct
    13081 tagtaccgcc gtgaggagag aacggcttat caaaagaggc aatgacatcg ttatccagtg
    13141 acctttccgc gccttcacgc cagtccagct cgccgttgtt gagccagggc tccagcgtat
    13201 agcgtttcag gccgaagcct gcgacagtat taacgtcttc gtgcagcaat ccggcattga
    13261 gcagctcacg catcaatacc ggtacgccgc ccgccgcctg gaagtggtta atgtccgccg
    13321 gaccgttcgg gtacagacgc gccatcaacg gaaccacttc cgacaaatcc gagaagtcat
    13381 cccagttgat cagaatgccc gccgcgcgcg ccattgcaac cagatgcatg gtgtggttgg
    13441 tggaaccgcc ggtagccagc agcgcgacaa tgccgttcac cacgactttt tcgtcgatca
    13501 ttttaccgag cggcatccac gtattgccgt tgccggtaag acgtgttacc tgacgtgcgg
    13561 cagcggcagt caatgcctcg cgcagcggcg catccggatg cacaaacgag gaacccggca
    13621 actgcattcc cataaactcc accaccatct ggttggtgtt ggcagtgccg taaaatgtac
    13681 aggtgcccgg cgcatggtaa gaggcggctt ccgactccag cagcgccatt ctgtctactt
    13741 ttccttccgc atatagctga cgaatacgga ctttttcttt attcggcagg ccgctcgcca
    13801 tcgggcctga cggaacaaaa atcgcgggta aatgaccaaa agagagcgcg gccatcgcca
    13861 gccccggaac aattttgtcg catacgccga ggaataacgc gccgtcaaac atattgtgag
    13921 aaaggcctac tgctgccgac atcgctatca cttcgcggct gagtaatgac aactccatgc
    13981 catcctgccc ttgcgtaacg ccatcgcaca ttgccggtac gccgcctgcg acctgaccta
    14041 ccgcattcac ggaatgcagg gcctgacgaa taatctgcgg ataatgttca tacggttgat
    14101 gcgcagagag catgtcattg taggaggtaa tgatggcgat attattgcgc aacatacttt
    14161 tcagcgaggc tttgtcctct ggctgacagg cggcgaagcc atgcgccagg ttgccgcagg
    14221 ccagttgaga tcggtggacc gtggcggttt tcgcctgctc aatgcgggca agataggctt
    14281 ttcgggtctg ctgcgagcgt tcgacaatgc gctgtgttac gcgtaacaaa ttaggattca
    14341 tagaggctcc tgaaatttat ctgtccggct accgggttta ccatgcgttt catcaatgtg
    14401 gaaagacagt gaaatacatg atgtccgggg ataatggggc aaaatcgttt caggcagtgt
    14461 aataaaaaaa gcctcgcagg tgaatccaca cgaggcttaa aagtgcaaaa atgattctac
    14521 aatctgtgtt agatcatgtt accggtaaaa taccacctaa gagtgagtgg caaatttact
    14581 caaactcatt ccacgaacga ccgtcacggg taatcatcgc cacggacgct accggtcccc
    14641 aggtgcccgc ctgatacggc ttcggcgcgt cgttgtccat cgcccatgct tcggtaatgg
    14701 agtccaccca cttccaggct tcttccactt cgtcacggcg gacaaacagc gcctgaatgc
    14761 cacgcatcgt ttccagcagc aggcgctcat atgcatccgc caggtgcgtc tgattaaagg
    14821 tctcggagta gctcagatca agcttcgtga tttgcagatt atgcttatga tccagcctcg
    14881 gtactttgtt aagtacctga atatctacgc cttcatccgg ctgcaggcga atcgtcaatt
    14941 tgttctgcgg caggtcttgc caggactctt taaagagatt cagttcaggc gtcttgaaat
    15001 aaaccacgac ttcagagcac ttagttggca gacgcttgcc ggtgcgcaga tagaatggca
    15061 cgcccgccca acgccagtta tcgatgtcga cgcggatcgc gacgaaagtt tcggtgttgc
    15121 tgcttttatt cgcgccctct tcttccagat agcccggcac cttttgaccc tgcgcaaagc
    15181 ccgcggtgta ttgaccacga accgtttttt cacgcacgtt ggagcgatca atacggcgca
    15241 acgatttcaa cacttttact ttttcatcgc gaatactgtc ggcgctcagg tcagacggcg
    15301 gtgacatggc aatcatgcag agaatttgca gcaagtggtt ctggatcata tcgcgcatct
    15361 gaccggcctg gtcaaaatat ccccagcgcc cttcaatccc cacctcttcc gctacggtaa
    15421 tctcaacgtg atcgatagtg cggttatccc agttattaac gaataacgag ttggcaaaac
    15481 gcagcgccag caggttgaga accgtttctt tgcccagata gtggtcgata cgatatactt
    15541 ggcactcttc aaagtattcg ccgacccgat cgttaatctc acgcgaggtc gccagcgaag
    15601 tacccaacgg tttctccatc acgacacgcg ccggtttggc gttgagttta gcctccccta
    15661 accctttgca aatagcgcca aacgtgctgg gcggcatcgc aaaatagtta atggtggtgc
    15721 ggtttttttg atccagcata tcgcccaggc gactgaacgc aggcgtatcg ttaacgtcaa
    15781 gattacaaaa atccagacgg ccgctcagcg tatcccacaa gccttcatca attttttcct
    15841 tcatgaaggt ttccagcgcc tcacgcacaa cgtgggtata agcttcttta tcccagtccg
    15901 cgcgccccac cccaatgatc cgggtatccg gatggatctg gccggctttc tcaagctgat
    15961 acagggaagg cagcagtttc cggcgcgcca ggtcgccttt cgcgccgaaa atgaccaggt
    16021 cacatgcctg ggctgtttgc gttaccgcca tgtcattctc ctcagttaat ctcctggtac
    16081 tttagccagg atatcgttgt aattttatta cacagcactg tactgctttt acgagattac
    16141 ggaaaccgta aacgcctttt cataggtgaa ccggcgtttg attggcaata taatcggcaa
    16201 aacgcctaat aaaattgtcg cttttccaca caagctggaa cttaaaatcc gacgtcggtc
    16261 atgtaatgaa aaaaaacgac acctttttta gccattttgc cccctttgac agccgccagg
    16321 agtaatatct aacaaaacgc gctcggtttc gcgcatcatt gaaatcgcta atacccatga
    16381 gccttgctaa tcatgaatat gctggaaaaa gtccagtctc aactggaaca tttaagcaaa
    16441 tctgaacgaa aagtcgccga tgttattctg gccgccccag gcagatcgat tcacttaagc
    16501 attgccatgc tggcccagga agctaacgtt agcgagccaa cggtgaaccg tttctgtcgc
    16561 agcatgaata cccgcggctt tcctgatttt aaactgcatc tggcgcaaag tctggcaaat
    16621 ggcaccccct atgttaatcg caatgtggat gaagatgaca gcgttgaggc ctatacagga
    16681 aaaatcttcg agtccgccat ggccagtctc gaccatgttc gtcagtcgct ggataaatcg
    16741 gccgtcaacc gcgccgtcga tttactgacc caggcaaaaa aaatcgcctt ttttggtctt
    16801 ggttcctccg ccgcggtcgc gcatgacgcc atgaataagt tttttcgctt caatgtgccg
    16861 gtgatttact ccgacgatat cgtgctgcaa cggatgagct gtatgaattg taacgatgat
    16921 gacgtcgtcg tgctcatttc gcatactggc agaaccaaga gcctggtgga actggcgcag
    16981 ttggcgcggg aaaacgatgc gatggtgatc gccctgacct ccgctggaac gccgctggcg
    17041 cgcgaagcca cgctggccat taccctcgac gtaccggaag atacagacat ttatatgccc
    17101 atggtctctc gacttgctca actgaccgtg atagatgtgc tggcaacggg atttactttg
    17161 cgtcgcgggg caaaattcag agataacttg aagcgtgtca aggaagcgct caaggaatcg
    17221 cgttttgata aagaattact catcaggagt gatgaccgct aaaagcaata acaatgttct
    17281 acccttttcg tcatccgggg acgttcattt tataccgtta aggtttcaga acgaccggat
    17341 caatgttcac gcaacaccaa gttgttttag tcaacggagt attacatgtc cagaaggctt
    17401 cgcagaacca aaatcgttac cacgttaggc ccggcaactg accgcgataa caaccttgag
    17461 aaggttatcg ccgcgggcgc aaacgtagta cgtatgaact tctctcacgg ctcgccggaa
    17521 gatcataaaa tgcgtgctga taaagtccgt gagattgccg ccaaattggg gcgtcatgtg
    17581 gctattttag gcgacctgca agggccaaaa attcgcgttt ccacttttaa agaaggcaaa
    17641 gtgttcctca atatcgggga caaatttctg ttagacgcta acctgggtaa aggcgaaggc
    17701 gataaagaaa aagtcggcat tgattacaaa gggttgccgg cagacgtcgt tcctggcgat
    17761 atcctgctgc ttgacgatgg tcgagtgcag ttgaaagtgc ttgaagtcca gggcatgaaa
    17821 gtctttaccg aggtcaccgt cggcggcccg ctgtctaaca ataaaggcat taacaagctc
    17881 ggcggcgggc tttctgctga agcgctgacc gaaaaagata aagccgatat tcaaaccgct
    17941 gcgctgatag gcgttgacta tctggcagtc tccttcccgc gctgcggcga agatctgaac
    18001 tatgcacgcc gcctggcgcg cgacgccggc tgtgacgcga aaattgtggc taaagtcgaa
    18061 cgcgccgaag cggtatgcga tcaaaacgct atggacgata tcattctggc ctctgacgtt
    18121 gtgatggtcg cacgtggcaa cctgggcgtt gaaatcggcg atccggagct ggttggtatc
    18181 cagaaggcgc tgattcgccg tgcgcgtcag ctaaaccgcg cagtcatcac cgcaacgcag
    18241 atgatggagt cgatgatcac caacccgatg ccgacccgtg cggaagtgat ggacgtggcg
    18301 aacgccgtcc tggatggcac ggatgcagtt atgctgtctg ccgaaaccgc agccggtcag
    18361 tatccttctg aaaccgttgc cgcaatggcg cgcgtctgtc tgggcgcaga aaaaatcccc
    18421 agcatcaatg tgtctaaaca ccgtctcgac gtgcagttcg acaatgttga agaagccatt
    18481 gccatgtctg cgatgtatgc ggcaaaccat ctgaaaggcg ttaccgcgat catcaccatg
    18541 acggaatccg gtcgtaccgc gctaatgact tcccgtatca gctccggcct gccgattttc
    18601 gccatgtcgc gccatgaacg cacgctgaac ctgaccgcgc tctaccgcgg agtaacgccg
    18661 gtgcattttg atagcgcggc tgatggcgtt gtcgcggcgc atgaagctgt taatctgctg
    18721 cgcgataaag ggtatctggt ttccggtgac ctggttatcg tgacccaggg cgatgtcatg
    18781 agcaccgtcg gttcaaccaa taccacgcgt attttgaccg ttgagtaaag ctccccctgg
    18841 cctgctcatc aggtaataca gggtttgtca gcataaagcc tctcttacga gaggctttat
    18901 ttatttgatg ggataaagat ctttacgctt atacggctga atctcgcctg gcttgcgggt
    18961 tttgagcaac ttcagaatcc aggtgtactg ttccggatgc gggccgacaa aaatttcgac
    19021 ctcttcgttc atccgtctgg cgatagtgtg gtcgtcagcc gtgagcagat cgtccattgg
    19081 cggacgaatc tggatagtca ggcgatgcgt tttaccatta tacaccggga aaagcggtat
    19141 cacgcgtgcg cggcacactt tcatcagccg accaattgca ggcagcgttg ctttgtatgt
    19201 cgcaaagaaa tcaacgaatt cactatgctc cgggccatga tcctggtccg gcaggtagta
    19261 accccagtag ccctgacgaa cagactgaat aaagggttta atcccgtcat tgcgcgcatg
    19321 caaacgtccg ccaaaacgcc gacgcacggt attccagata tagtcaaaaa ccggattacc
    19381 ctgattatga aacatcgccg ccattttttg cccctgagag gccatcagca tggctggaat
    19441 gtcgacgccc cagccatgcg gtacgagaaa aataactttt tcgtcgttac gacgcatctc
    19501 ctcgataatc tccagacctt cccagtcaac acgctgttga atttttttcg gaccgcgcat
    19561 cgccagctca gccatcatcg ccattgcctg cggcgcggtg gcgaacatct catcgacaat
    19621 cgcttcgcgt tcagcttcgc tacgctgcgg aaagcacaat gacagattaa ttagcgcccg
    19681 gcgacgagaa ctcttcccca gccgtccggc aaaacgcccc agcgtcgcca gcaaagggtc
    19741 gcggaatgat gccggcgtta atgcgatccc cgccattgcc gcagcgccca accaggcgcc
    19801 ccaatactgc ggatagcgaa aggatttttc gaattcaggg atatactcac tattattttt
    19861 tttggtttcc atgcttttcc agggtctgct gacgcgaaaa ggaattgtga atagtgtagc
    19921 gatgtctgcg ccgcacacaa aacaaaacag ccggcacaca tcgcgtaccg gctctgtcaa
    19981 cgcatttgtt aatcgaagcg cagttgcggc agaatctctt tcacctgtgc caggtattca
    20041 cgacgatctg accccgtcag accttccgtg cgcggcaatt ttgctgtcag agggttaacg
    20101 gcttgctggt tgatccatac ctcataatgc agatgcggcc ctgtggaacg cccggtgtta
    20161 ccagaaagcg caatacgatc gccacgtttc actttttgcc ccggtttcac cagcagctta
    20221 cgcaagtgca tgtaacgtgt ggtgtaggtg cgtccatgac gaatcgcaat gtagtaaccg
    20281 gcagcgccgc tacgtttagc aaccacgacc tcgccatccc ccaccgacag caccggcgta
    20341 ccctgcggca tcgcaaagtc aacgccacga tgcggcgcaa cgcgtccggt aaccgggttc
    20401 agacgacgcg gattgaagtt ggaggagatg cggaactgtt tggcggtcgg gaagcgtaaa
    20461 aagcctttcg ccaggccaac accgttacgg tcatagaatt taccgtcagc ggcgcgaatg
    20521 gcgtagtaat ctttaccatc ggaacgcata cgcacgccca acaactgact ctgttcacgc
    20581 ttgccatcca gcatctcacg cgacatcaga accgaaaatt catcgccctt tttcagcttc
    20641 cgaaaatcca tctgccactg cattgctttt atcactgcgc tgatttcgct gctggttaaa
    20701 ccagcctctt tcgcgctggc gacaaagctg ccccctaccg tgcctttcag cagactgttg
    20761 acccagtccc cctgctgcat ttcactgctc attttaaaac cgttggcagt gcgatcgtag
    20821 gtacgcgttt cacggcggga gacttcccat gtcagacgct gtaaatcgcc atcggcggtc
    20881 agtgtccagg aaagctgttg gccaattttc agattgcgca gctccttatc agaagcggca
    20941 agtcggctaa tatcgctcat atcgatgccg tactgattca gaatactgct taacgtatcg
    21001 cctgtggaga cgacgtattc atggacgccg acttcgcctg cggttttatc gtccagctca
    21061 tcctgaggaa tagcttcatc ttcctgcgcg gcctgatcga tgggttcgct ggcctccggt
    21121 aagagggaac gaatctcgct tttctccagt tcaatagttt taacgattgg tgcggattct
    21181 gggtggtaaa catagggccg ccatacggcg acggccagtg tcagaacggt aagtgacccc
    21241 agcataacgc ggtggggtcg gggcagatta ttaaatgcca gggcgacaga gccggctatc
    21301 tgttgcacgt attcacttcc tcgttaatct cctttcaggc agctcgcata ctggttggct
    21361 aattggctta aaaacgctga atagcttgtt ttacccagtt taatgttcgt cccgaggggg
    21421 tccagtgttc ccattcgaac ggatgtccct ctcgccacgg cttccacgac cgctggcctg
    21481 aattgtggct cagcaaaaac gcaggttgct ttttgctcaa ccaactgtgt tcttatttca
    21541 tgtaaacgct gcgcgccagg ttgtatctca gggttcacgg taaagtgacc gagtggggtg
    21601 agtccgtagt gtttttcgta gtaaccgtag gcgtcatgaa aaacgaaata ccctttcccc
    21661 ttgagcggcg cgagctcgtt accgacctgt ttatcggttg cggctaattg tgcctcaaaa
    21721 tccttcaggt tggcgtcgag tttagctcga ctttgcggca taagttccac taatttttca
    21781 tggattgcaa ccgctgtagc ccgcgctatc tctggggaga gccaaagatg catgttatat
    21841 tcgccgtgat ggtgatgtac gtcacctttt tcctcatcgg cgcccgtatg cgcatgttca
    21901 tcctcatcat catccgcgcc cttcatgagt aacggtttta catcggcaag ttgcgcaatg
    21961 gtaacctgct tattatcagg gatattcctg accgacttct ccataaaggc ttccatttcc
    22021 gggccaaccc agacgactaa gtccgcgccc tgtaagcgtt ttacgtctga tggacgcaat
    22081 gaataatcat gctcggatgc cccatccgga agtaatactt gcgtatccgt aacgccatca
    22141 gcaatggcgg aagcaataaa cccaagcggt ttaagcgaag cgacaacggc ggcgtcggca
    22201 gcctgggttg cactccccca aagcgcggcg gataatgctg cgaaaagaag cgtatttttc
    22261 tgtaacataa tgcgactaat catcgtaatg aatatgtgaa atgtgatatt ataacattct
    22321 atcacttctg caagcctaaa attaacatga caagtttagt ttcactggaa aacgtctcgg
    22381 tctcatttgg tcaacgccgc gtcctctctg acgtgtcgct tgaattgagc cccggaaaaa
    22441 ttttaacgct tctcggccct aacggtgcgg ggaagtcaac gcttgtacgc gtggttttag
    22501 gactggtagc ccctgatgaa ggggtgatca agcgcaacgg gcaactccgt atcggctatg
    22561 tcccgcaaaa gctctatctc gataccacgc ttccgctgac ggtaaaccga tttttacgtt
    22621 tacgtccctg cacgcaaaaa acggatattc tcccggcgct taaacgcgtt caggccggac
    22681 atttgattga cgcgcccatg caaaaactct ccggcggtga gacacagcgc gtactgctgg
    22741 cccgtgctct gcttaacagg ccgcagttgc tggtacttga tgagccgacg caaggcgtgg
    22801 atgtcaacgg ccaggtcgcg ttatacgacc ttatcgatca gctgcgccgt gaactcgatt
    22861 gcgccgttct gatggtgtcg catgatctac atctggtcat ggcaaaaacg gatgaagtgt
    22921 tatgcctgaa ccatcatatt tgctgttccg gcgcgccgga agtggtgtct atgcatccgg
    22981 aatttatctc tatgtttggc ccgcgtggcg cggagcaatt agggatttat cgccatcatc
    23041 ataatcatcg ccacgattta cagggtcgta ttgtactgcg ccggggaaat ggtcactcat
    23101 gattgaatta ttactgcccg gctggctggc cgggatgatg ctggcctgcg ctgctggtcc
    23161 gttgggctca tttgtggtct ggcgtcggat gtcctatttt ggcgatacgc tggctcacgc
    23221 gtcgcttctg ggcgtggcgt ttggcctgtt gctggacgtt aacccctttt atgcggtaat
    23281 cgccgttacg ctgctgctgg cctccggtct ggtatggctg gagaaacgcc ctcacctcgc
    23341 gattgatacc ttactgggca ttatggcaca cagcgccttg tctttaggac tggtcgtggt
    23401 cagcctgatg tccaacgtcc gcgttgattt aatggcttat ctgtttggcg atttgctggc
    23461 cgtgacgccg gaagatctta tctcgatcgc tattggggtc gttattgtgc tggccattct
    23521 cttctggcag tggcgcaact tgctgtcaat gactatcagt ccggatcttg cctttgtcga
    23581 tggcgtgaag ttacagcgcg tgaagctgct attgatgctg gtaacggcgt taaccattgg
    23641 cgtaacgatg aagtttgtcg gagcgctgat tatcacctcg ctgctgatta tccccgccgc
    23701 aaccgcgcgt cgctttgccc gtacgccgga gcagatggcg ggcgtcgccg ttggtgtagg
    23761 tatgatagcg gttacaggtg gactgacctt ctcagccttt tatgataccc cggcagggcc
    23821 atccgtagtg ctgtgtgccg cgctgctgtt tatcttcagt atgatgaaaa agcaggcaag
    23881 ctaagcgtgt gttgcccggt ggcgctgcgc ttaccgggcc tacaaaatcg cccaggcctg
    23941 atgagcgcag cgacttcagg cgttaaggca tctctggcgg cgtaatacca aagtggttcc
    24001 aggcgcgcac cgttgccata cgcccacgcg gcgtgcgctg caaaaagcct tgctgaatca
    24061 gatacggctc cagcacatcc tcaatggttt cacgctcttc gccaatcgcc gccgccagat
    24121 tatccagtcc caccgggcca ccgaagaatt tatcaataac cgccagcagt agcttgcgat
    24181 ccatataatc aaacccttcc gcatcgacgt tcagcatatc cagcgcctgc gcggcaattt
    24241 ccgctgaaat agccccgtca tgcttcacct cagcaaaatc acgcacacgt ctgagcaggc
    24301 ggttggctat acgcggcgta ccgcgcgccc gacgcgccac ttccagcgcg ccgtcatcgc
    24361 tcatctcaag ccccatgtgc cttgcgctgc gcccgacgat gtgctgcaga tcgggcacct
    24421 ggtagaactc caggcgctgc acaataccaa aacggtcacg tagcggggac gttaacgacc
    24481 cggcgcgcgt cgtcgcgcca atgagcgtaa acggcggcag atcgatttta attgaacgtg
    24541 cagccggccc ttcgccaatc ataatatcca actggtaatc ttccatcgcc ggatagagta
    24601 cctcttccac caccggtgaa agccggtgga tctcatcaat aaacagcaca tcatgcggtt
    24661 caagattggt gagcatagcc gccagatcgc ctgctttttc cagcaccggg ccggacgtgg
    24721 ttcggaggtt gacgcccatt tcattggcaa cgatattcgc cagagtcgtt ttacctaacc
    24781 ctggcgggcc gaaaatcagc aagtgatcta atgcgtcgcc acgccgtttt gccgcctgaa
    24841 taaagatctc catctgggag cgcacctgcg gttggccgac atattccgcc aataacttcg
    24901 ggcgaatggc gcgatcggcg acgtcttctg cgatcgtggc gcctgctgaa atcaggcgat
    24961 ctgcttctat catcctttac ctcatagcgc ggcgcgtaac gcgtcgcgaa tcagtgtttc
    25021 actgcttgcg tccggacggg cgatcttact taccatccga ctggcttctt gcggtttata
    25081 acccagcgcc accagcgcag caactgcttc ttgttctgca tcttccgagg ttgggctggc
    25141 cggcgacgtc aataccagat cgaccgctgg cgtaaagaga tcgccatgta gccctttaaa
    25201 gcggtctttc atttcgacaa tcagcctttc ggcggttttc ttgccgatac ccggcagctt
    25261 caccagcgca cccagctctt cgcgctcaac cgcattcaca aactgctgcg ccgacatgcc
    25321 ggagaggatc gccagcgcca gcttaggccc gacgccattc gttttaatta gctctttaaa
    25381 tagcgtgcgc tcttgcttat tgttaaatcc gtacagcaac tgcgcatctt cacgcaccac
    25441 gaagtgggtg aagacgattg cctcctgccc ggcctccggc agctcgtaaa agcaggtcat
    25501 aggcatatgt acttcatagc ctacgccccc tgtctccagc agcacgatcg ggggttgttt
    25561 ttcgagaata atgcctctga gtctgcctat cacatgacgc tcctgcgtaa agggctgaaa
    25621 agataatgca ctatcataaa aaaagactgg atgtttatcc agatgaaaaa cacttatccc
    25681 gatatttctg tactccgaca acccgcgata gttaacgacg ggcacgctcc ccgctgcgta
    25741 caaaataagt cgtacactca ttgacaactt tttgcgtcct acgcgaataa ctttttgcca
    25801 acatgccgtg gcgcaagttt ggtagtcttc aataatgagt atcctgataa cactaatact
    25861 gtatccagta cgaatgccaa cagcggaaca tcggtccccc caaaaaacag acccgagaat
    25921 agatttaata aaattaacca ctagcgctga atttaatcgc atgttgtttt atcgtcgcgc
    25981 acaacatatt ttaattcacc atgacacaat aaatattgtg caaactcatt tttcatgcca
    26041 tcgaaattca cggctggtat cccttctgaa taactataat aaatattcac atactcttca
    26101 ctactaaaaa gtgcctgtcg ttttgctgct aacccacggc cttttgctgc a
//
LOCUS       DAJVBX010000039        25903 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.039, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000039 DAJVBX010000000
VERSION     DAJVBX010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 25903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25903
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.039"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(120..821)
                     /gene="fre"
                     /locus_tag="OPV72_001451"
     CDS             complement(120..821)
                     /gene="fre"
                     /locus_tag="OPV72_001451"
                     /EC_number="1.5.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-flavin reductase"
                     /protein_id="HCR9913801.1"
                     /translation="MTTLSCKVTSVEAITDTVYRVRLVPDAAFSFRAGQYLMVVMDER
                     DKRPFSMASTPDEKGFIELHIGASELNLYAMAVMDRILKDREIVVDIPHGDAWLRDDE
                     ERPLILIAGGTGFSYARSILLTALARNPARDVTIYWGGREEKHLYDLSELEALSVNHP
                     NLRIEPVVEQPEEGWRGRTGTVLTAVLQDYGTLAGHDIYIAGRFEMAKIARDLFCHER
                     NAREDRLFGDAFAFI"
     gene            complement(907..2385)
                     /gene="ubiD"
                     /locus_tag="OPV72_001452"
     CDS             complement(907..2385)
                     /gene="ubiD"
                     /locus_tag="OPV72_001452"
                     /EC_number="4.1.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-polyprenylbenzoate decarboxylase"
                     /protein_id="HCR9913802.1"
                     /translation="MDAMKYHDLRDFLTLLEQQGELKRITLPVDPHLEITEIADRTLR
                     AGGPALLFENPKGYAMPVLCNLFGTPKRVAMGMGQDDVSALREVGKLLAFLKEPEPPK
                     GFRDLFDKLPQFKQVLNMPTKRLRGAPCQQKIASGDDVDLTRLPVMTCWPDDAAPLIT
                     WGLTVTRGPHKERQNLGIYRQQLIGKNKLIMRWLSHRGGALDFQEWLAARPGERFPVS
                     VALGADPATILGAVTPVPDTLSEYAFAGLLRGTKTEVVKCLSNDLEVPASAEIILEGY
                     IEPGEMAPEGPYGDHTGYYNEVDNFPVFTVTHITQREDAIYHSTYTGRPPDEPAVLGV
                     ALNEVFVPILQKQFPEIVDFYLPPEGCSYRLAVVTMKKQYAGHAKRVMMGVWSFLRQF
                     MYTKFVIVCDDDVNARDWNDVIWAITTRMDPARDTVLVENTPIDYLDFASPVSGLGSK
                     MGLDATNKWPGETQREWGRPIVKDPEVTARIDAIWDELAIFK"
     gene            2571..3059
                     /gene="rfaH"
                     /locus_tag="OPV72_001453"
     CDS             2571..3059
                     /gene="rfaH"
                     /locus_tag="OPV72_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription/translation regulatory transformer
                     protein RfaH"
                     /protein_id="HCR9913803.1"
                     /translation="MQSWYLLYCKRGQLQRAQEHLERQAVSCLTPMITLEKMVRGKRT
                     FVSEPLFPNYLFVEFDPEVIHTTTINATRGVSHFVRFGAHPAIVPSSVIHQLSIYKPE
                     GVVDPETPYPGDSVIITEGAFEGLKAIFTEPDGETRSMLLLNLLNKEVKQSVKNTGFR
                     KI"
     gene            complement(3067..3849)
                     /gene="tatD"
                     /locus_tag="OPV72_001454"
     CDS             complement(3067..3849)
                     /gene="tatD"
                     /locus_tag="OPV72_001454"
                     /EC_number="3.1.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462861.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' ssDNA/RNA exonuclease TatD"
                     /protein_id="HCR9913804.1"
                     /translation="MFDIGVNLTSSQFAKDRDDVVARAFAAGVKGMLLTGTNIHESQQ
                     ALKLARRYPHCWSTAGVHPHDSSQWSSASEDAIIALANQPEVVAIGECGLDFNRNFST
                     PQEQERAFQAQLQIAAELQMPIFMHCRDAHERFLALLDPWLDSLPGAILHCFTGSRQQ
                     MQACVDRGLYIGITGWVCDERRGLELRELLPFIPAEKLLIETDAPYLLPRDLTPKPTS
                     RRNEPAYLPHILERIALWRGEDPQWLAAMTDANARTLFEVVF"
     gene            complement(3891..4670)
                     /gene="tatC"
                     /locus_tag="OPV72_001455"
     CDS             complement(3891..4670)
                     /gene="tatC"
                     /locus_tag="OPV72_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sec-independent protein translocase subunit
                     TatC"
                     /protein_id="HCR9913805.1"
                     /translation="MAVEDTQPLITHLIELRKRLLNCIVAVLLIFLALIYFANDIYHL
                     VAAPLIKQMPQGATMIATDVASPFFTPIKLTFMVSLILSAPVILYQVWAFIAPALYKH
                     ERRLVVPLLVSSSLLFYIGMAFAYFVVFPLAFGFLTHTAPEGVQVSTDIASYLSFVMA
                     LFMAFGVAFEVPVAIVLLCWMGITTPEDLRKKRPYILVGAFIVGMLLTPPDVFSQTLL
                     AIPMYCLFEIGVFCSRFYVGKRRTRDEDNEAETEKAEHTED"
     gene            complement(4673..5221)
                     /gene="tatB"
                     /locus_tag="OPV72_001456"
     CDS             complement(4673..5221)
                     /gene="tatB"
                     /locus_tag="OPV72_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sec-independent protein translocase subunit
                     TatB"
                     /protein_id="HCR9913806.1"
                     /translation="MFDIGFSELLLVFVIGLIVLGPQRLPVAVKTVAGWIRALRSLAT
                     TVQNELTQELKLQEFQDSLKKVEKASLENLTPELKASMDELRQAAESMKRTYSANDPE
                     QASDEAHTIHNPVVKGNETQHEGVTPAAAETQASAPEQKPEPVKANVPESTETASVAA
                     IDAEKKSAAPVVESSPSSSDKP"
     gene            complement(5225..5479)
                     /gene="tatA"
                     /locus_tag="OPV72_001457"
     CDS             complement(5225..5479)
                     /gene="tatA"
                     /locus_tag="OPV72_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sec-independent protein translocase subunit
                     TatA"
                     /protein_id="HCR9913807.1"
                     /translation="MGGISIWQLLIVAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMS
                     DDDAKQDKTSQDADFTAKSIADKQGEAKKEDAKSQDKEQV"
     gene            complement(5685..7325)
                     /gene="ubiB"
                     /locus_tag="OPV72_001458"
     CDS             complement(5685..7325)
                     /gene="ubiB"
                     /locus_tag="OPV72_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone biosynthesis regulatory protein
                     kinase UbiB"
                     /protein_id="HCR9913808.1"
                     /translation="MTPGEVRRLYFIIRTFLSYGLDELIPRMRLTLPLRLWRYSLFWM
                     PNRHKDKLLGERLRLALQELGPVWIKFGQMLSTRRDLFPPQIADQLALLQDKVAPFDG
                     RLAKAQIEEAMGGLPVEAWFDDFDIQPLASASIAQVHTARLKSNGKEVVIKVIRPDIL
                     PVIQADLKLIYRLARWVPRLLPDGRRLRPTEVVREYEKTLIDELNLLRESANAIQLRR
                     NFENSPMLYIPEVYSDYCSQNMMVMERIYGIPVSDVAALEKNGTNMKLLAERGVKVFF
                     TQVFRDSFFHADMHPGNIFVSHEHPENPQYIGIDCGIVGSLNKEDKRYLAENFIAFFN
                     RDYRKVAELHVDSGWVPPDTNVEDFEFAIRTVCEPIFEKPLAEISFGHVLLNLFNTAR
                     RFNMEVQPQLVLLQKTLLYVEGVGRQLYPQLDLWKTAKPFLESWIKDQVGIPALTRAL
                     KEKAPFWVEKMPEIPELVYDSLRQGKYLQHSVDKIARELQVNHVRQSQSRYLLGIGAT
                     LLLSGSFLLVNRPEWGLMPGWLMVGGVVVWLVGWRKTR"
     gene            complement(7322..7927)
                     /gene="ubiJ"
                     /locus_tag="OPV72_001459"
     CDS             complement(7322..7927)
                     /gene="ubiJ"
                     /locus_tag="OPV72_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone biosynthesis protein UbiJ"
                     /protein_id="HCR9913809.1"
                     /translation="MPFKPLVTAGIEGLLNTFLYRSPALKSARTRLQGKVLCVKLKGF
                     STPLVLVFSERQVDVLGAWEGEADCTVITQASVLPKLRDRQQLAALIRSGELEVQGDI
                     QVVQNFVALADLAEFDPAELLAPYTGDIAAESIGKVVRGGAKFLRHGFQRQQRYAAEA
                     ITEEWRMAPGPLEVAWFAEETAAVERAVDSLTTRLEKLGAK"
     gene            complement(7937..8692)
                     /gene="ubiE"
                     /locus_tag="OPV72_001460"
     CDS             complement(7937..8692)
                     /gene="ubiE"
                     /locus_tag="OPV72_001460"
                     /EC_number="2.1.1.163"
                     /EC_number="2.1.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional demethylmenaquinone
                     methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol
                     methylase UbiE"
                     /protein_id="HCR9913810.1"
                     /translation="MVEDSQETTHFGFQTVAKEQKADMVAHVFHSVASKYDVMNDLMS
                     FGIHRLWKRFTIDCSGVRRGQTVLDLAGGTGDLTAKFSRMVGETGKVILADINDSMLK
                     MGREKLRNIGVIGNVEYVQANAEALPFPDNTFDCITISFGLRNVTEKEKALRSMFRVL
                     KPGGRLLVLEFSKPIIEPLSKAYDAYSFHILPRIGSMVANDADSYRYLAESIRMHPDQ
                     DTLKAMMQDAGFESVDYYNLTAGVVALHRGYKF"
     gene            complement(8788..10218)
                     /gene="rmuC"
                     /locus_tag="OPV72_001461"
     CDS             complement(8788..10218)
                     /gene="rmuC"
                     /locus_tag="OPV72_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HCR9913811.1"
                     /translation="MDITLMISAVVALAAGAVIGWLATKAHADQIRADLIEERRELDI
                     ELSAARQQLAQEAHWRSECELLNNELRSLHSINTSLEADLREVTTRLEATQQHAEDKI
                     RQMINSEQRLSEQFENLANRIFEHSNRRVDEQNRQSLNSLLTPLREQLDGFRRQVQES
                     FGKEAQERHTLAHEIRNLQQLNAQMAQEAINLTRALKGDNKAQGNWGEVVLARVLEAS
                     GLREGYEYETQVSIENDARSRMQPDVIVRLPQGKDVVIDAKMTLVAYERYFNAEDDYT
                     REAALQEHIASVRNHIRLLGRKDYQQLPGLRSLDYVLMFIPVEPAFLLALDKQPELIT
                     EALKNNIMLVSPTTLLVALRTIANLWRYEHQSRNAQHIADRASKLYDKMRLFVDDMSA
                     IGQSLDKAQDNYRQAMKKLASGRGNVLAQAEAFRGLGVEIKREINPDLAEQAVTQDEE
                     YRLRSIPEGRQDEHYPNDERVKQQLS"
     gene            complement(10358..11119)
                     /gene="udp"
                     /locus_tag="OPV72_001462"
     CDS             complement(10358..11119)
                     /gene="udp"
                     /locus_tag="OPV72_001462"
                     /EC_number="2.4.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine phosphorylase"
                     /protein_id="HCR9913812.1"
                     /translation="MSKSDVFHLGLTKNDLQGAQLAIVPGDPERVEKIAALMDKPVKL
                     ASHREFTSWRAELDGKAVIVCSTGIGGPSTSIAVEELAQLGIRTFLRIGTTGAIQPHI
                     NVGDVLVTTASVRLDGASLHFAPMEFPAVADFACTTALVEAAKSIGATTHVGVTASSD
                     TFYPGQERYDTYSGRVVRRFKGSMEEWQAMGVMNYEMESATLLTMCASQGLRAGMVAG
                     VIVNRTQQEIPNAETMKQTESHAVKIVVEAARRLL"
     gene            11378..12190
                     /locus_tag="OPV72_001463"
     CDS             11378..12190
                     /locus_tag="OPV72_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HCR9913813.1"
                     /translation="MTTTHPSGFAPAASPLAPTMIHTPDGAISAGITSIPSQGDDMPA
                     YYARPKASDGALPVVIVVQEIFGVHEHIRDICRRLALEGYLAIAPELYFREGDPNDFA
                     DIPTLLSGLVAKVPDSQVLADLDHVASWASRNGGDAHRLMITGFCWGGRITWLYAAHN
                     PQLKAAVAWYGKLVGDTSLNSPKHPVDIATDLNAPVLGLYGGQDTSIPQESVETMRQA
                     LRAANAKAEIVVYPDAGHAFNADYRPGYHEASAKDGWQRMLEWFAQYGGKKG"
     gene            complement(12266..13564)
                     /locus_tag="OPV72_001464"
     CDS             complement(12266..13564)
                     /locus_tag="OPV72_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001785009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfatase maturase"
                     /protein_id="HCR9913814.1"
                     /translation="MAVAGCHVMAKPGGAICNIDCTYCFYLEKEALYPERNKNWRMSD
                     ETLEQFIRQHIAAQSGDRIDFAWQCGEPTMMGLPFFRRVVALCEKYGDGRKITHALQT
                     NGILVNDEWARFFAEQHFLIGLSIDGPASLHNHYRLNRAGKGTHEQVVAAMARLKAHH
                     VDFNTLTVVGKHNVGHAADVYEFLLAAGSRFIQFIPLVERMSTDNSSVLNLVMPGESA
                     AKLAPWTVPSWQYGEFLNQIFDIWVRRDVDRVYVQMFDVALAAWTAQQPVLCVHSETC
                     GHAFALESNGDLYNCDHFVYPEHLLGNIHQHSIKTLNNSERAIAFGEAKRETLTADCR
                     RCDYRFACHGGCPKHRFAVSPSGHPAHNYLCTGYKHFFQHVTPYMNVWRELLAQGYPM
                     ASIMRWLAQDARKDTGAVSRNHLCPCGSGKKYKNAVVKHS"
     gene            complement(13947..16211)
                     /gene="metE"
                     /locus_tag="OPV72_001465"
     CDS             complement(13947..16211)
                     /gene="metE"
                     /locus_tag="OPV72_001465"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HCR9913815.1"
                     /translation="MTILTHTLGFPRVGLRRELKKAQESYWAGNTTREALLAVGRELR
                     ARHWEQQKQAGIDLLPVGDFAWYDHVLTTSLLLGNVPARHQNNDGSVDIDTLFRIGRG
                     RAPTGEPAAAAEMTKWFNTNYHYIVPEFSKGQQFRLTWTQLLEEVDEALALGHKIKPV
                     LLGPVTYLWLGKVKGEPFDRLTLLKDILPVYQHVLAELAKRGVEWVQIDEPALVLELP
                     QAWLDAFKPAYDALAGQVKLLLTTYFEGVTPNLDTIIVLPVQGLHVDLIHGKDDVVEL
                     HQRLPVDWLLSAGLINGRNVWRADLTEKYAQINAIVGKRALWVASSCSLLHSPIDLSV
                     ETRLDTEVKSWFAFALQKCGELALLRDALNSGETAALEEWSVPIQARRHSHRVHNAAV
                     EKRLAAITAQDSQRENPYEVRAEAQRARFKLPAWPTTTIGSFPQTTEIRGLRLDFKKG
                     NLDANNYRTGIAEHIKQAIIEQERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGW
                     VQSYGSRCVKPPVVIGDISRPAPITVEWAKYAQSLTDKPVKGMLTGPVTILCWSFPRE
                     DVTRETIAKQIALALRDEVADLEAAGIGIIQIDEPALREGLPLRRSDWDAYLEWGVEA
                     FRINAAVAKDETQIHTHMCYCEFNDIMDSIAALDADVITIETSRSDMELLESFEAFDY
                     PNEIGPGVYDIHSPNVPSVEWIEALLKKAAQRIPAQRLWVNPDCGLKTRGWPETRAAL
                     ANMVKAAHNLRQAK"
     gene            16460..17413
                     /gene="metR"
                     /locus_tag="OPV72_001466"
     CDS             16460..17413
                     /gene="metR"
                     /locus_tag="OPV72_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator MetR"
                     /protein_id="HCR9913816.1"
                     /translation="MIEIKHLKTLQALRNSGSLAAAAAVLHQTQSALSHQFSDLEQRL
                     GFRLFVRKSQPLRFTPQGEVLLQLANQVLPQISRALQACNEPQQTRLRIAIECHSCIQ
                     WLTPALENFRASWPQVEMDFTSGVTFDPQPALQQGELDLVMTSDILPRSGLHYSPMFD
                     FEVRLVLAPDHPLASKTQITPEDLASETLLIYPVQRSRLDVWRHFLQPAGISPLLKSV
                     DNTLLLIQMVAARMGIAALPHWVVESVERQGLVVTKTLGDGLWSRLYAAVRDGDQRQA
                     VTEAFIRSTRDHACDHLPFVRSAERPIFDAPTAKPGSQPRL"
     gene            complement(17301..18200)
                     /locus_tag="OPV72_001467"
     CDS             complement(17301..18200)
                     /locus_tag="OPV72_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HCR9913817.1"
                     /translation="MALLIITTILWAFSFSLFGEYLAGHVDSYFAVLIRVGLAALVFL
                     PFLRTRGHNLKTISLYMLVGAMQLGIMYMLSFHAYLYLTVSELLLFTVLTPLYITLIY
                     DVMSQRRLRWGYAFSALLAVIGAGIIRYDRVTDHFWVGLLLVQLSNISFAIGMVGYKR
                     LMETRPMPQHNAFAWFYLGAFLVAAVAWSLLGNAQKLPETTLQWSILVFLGVVASGIG
                     YFMWNYGATQVDAGTLGIMNNMHVPAGLLVNLAIWHQQPHWPSFITGAAVILASLWVH
                     RKWVAPRSAQTADDRRRDPASSE"
     gene            complement(18281..19081)
                     /gene="yigL"
                     /locus_tag="OPV72_001468"
     CDS             complement(18281..19081)
                     /gene="yigL"
                     /locus_tag="OPV72_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar/pyridoxal phosphate phosphatase YigL"
                     /protein_id="HCR9913818.1"
                     /translation="MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGIHFVFATGR
                     HHVDVGQIRDNLEIKSYMITSNGARVHDTDGNLVFTHNLDSDIASDLFGVVNANPDIV
                     TNVYRDDEWFMNRHRPDEMRFFKEAVFNYSLFEPALLEPEGVSKVFFTSDTHEKLLPL
                     EQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAQAMGYSLKECIAFGDGMND
                     AEMLTMAGKGCIMGNAHQRLKDLYPELEVIGINADNAVPHYLRDLFLR"
     gene            complement(19097..20113)
                     /gene="pldB"
                     /locus_tag="OPV72_001469"
     CDS             complement(19097..20113)
                     /gene="pldB"
                     /locus_tag="OPV72_001469"
                     /EC_number="3.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipase L2"
                     /protein_id="HCR9913819.1"
                     /translation="MFQQQNDWETRENAFAAFAMGPLTDFWRQREEAEFIGVDNIPVR
                     FVRFRNDSNDRTIVICPGRIESYVKYAELAYDLFHLGFDIFIIDHRGQGRSGRMLSDP
                     HRGHVDHFNDYVEDLAAFWQQEIEPGSWRKRYILAHSMGGAIATLFLQRHRVRCDAIA
                     LTAPMFGIVIRLPSFMVRHILDWAEGHQRIREDYAIGTGQWRALPFGMNALTHSRQRY
                     QRNLRFYADEPQLRVGGPTWHWVREGILAGEQVLAGASDDTTPTLLIQAEEERVVDNR
                     THDRFCEIRAAAGYPCEGGKPLVIKGAYHEILFEKDAMRSVALNAIVEFFNKPNLSSG
                     NRFA"
     gene            20224..20844
                     /gene="rhtB"
                     /locus_tag="OPV72_001470"
     CDS             20224..20844
                     /gene="rhtB"
                     /locus_tag="OPV72_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine/homoserine lactone efflux protein"
                     /protein_id="HCR9913820.1"
                     /translation="MTFEWWFAYLLTSTLLSLSPGSGAINTMTTSINHGYRGAAASIA
                     GLQTGLGIHIVLVGVGLGTLFSRSLIAFEILKWAGAAYLIWLGIQQWRAAGAIDLHTL
                     AQTQSRGRLFKRAIFVNLTNPKSIVFLAALFPQFIMPQQPQLAQYLILGVTTIVVDMI
                     VMTGYATLAQRIAAWIKGPKQMKALNKAFGSLFMLVGALLASARHA"
     gene            complement(20884..21504)
                     /gene="rhtC"
                     /locus_tag="OPV72_001471"
     CDS             complement(20884..21504)
                     /gene="rhtC"
                     /locus_tag="OPV72_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine export protein RhtC"
                     /protein_id="HCR9913821.1"
                     /translation="MLMLFFTVAMVHIVALMSPGPDFFFVSQTAVSRSRKEAMMGVLG
                     ITCGVMVWAGVALLGLHLIIEKMAWLHTIIMVGGGLYLCWMGYQMLRGALKKQDAAAS
                     SPHIELAQSGRSFLKGLLTNLSNPKAIIYFGSVFSLFVGDNVGAAARWGIFALITLET
                     LAWFTVVASLFALPKMRRGYQRLAKWIDGFAGALFAGFGIHLIISR"
     gene            complement(21568..23397)
                     /gene="recQ"
                     /locus_tag="OPV72_001472"
     CDS             complement(21568..23397)
                     /gene="recQ"
                     /locus_tag="OPV72_001472"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026263.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HCR9913822.1"
                     /translation="MAQAEVLNLESGAKQVLQETFGYQQFRPGQEAIIDTALSGRDCL
                     VVMPTGGGKSLCYQIPALLLDGLTVVVSPLISLMKDQVDQLLANGVAAACLNSTQSRE
                     QQLEVMAGCRTGQIRLLYIAPERLMLDNFLDHLAHWNPVLLAVDEAHCISQWGHDFRP
                     EYAALGQLRQRFPALPFMALTATADDTTRQDIIRLLGLNDPLIQISSFDRPNIRYMLM
                     EKFKPLDQLMRYVQEQRGKSGIIYCNSRAKVEDTAARLQSRGISAAAYHAGLENAIRA
                     DVQEKFQRDDLQIVVATVAFGMGINKPNVRFVVHFDIPRNIESYYQETGRAGRDGLPA
                     EAMLFYDPADMAWLRRCLEEKPAGQLQDIERHKLNAMGAFAEAQTCRRLVLLNYFGEG
                     RQEPCGNCDICLDPPKQYDGLNDAQIALSTIGRVNQRFGMGYVVEVIRGANNQRIRDF
                     GHDKLKVYGMGREKSHEHWVSVIRQLIHLGLVMQNIAQHSALQLTDAARPVLRGDVPL
                     KLAVPRIVALKPRVMQKSFGGNYDRKLFAKLRKLRKAIADEENIPPYVVFNDATLIEM
                     AEQMPVSASEMLSVNGVGMRKLERFGKEFMALIRAHVDGDDEE"
     gene            complement(23481..24350)
                     /gene="pldA"
                     /locus_tag="OPV72_001473"
     CDS             complement(23481..24350)
                     /gene="pldA"
                     /locus_tag="OPV72_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase A"
                     /protein_id="HCR9913823.1"
                     /translation="MRAILRGLLPATLLPLAAYAQEATIKEVHDAPAVRGSIIANMLQ
                     EHDNPFTLYPYDTNYLIYTNTSDLNKEAISTYNWSENARKDEVKFQLSLAFPLWRGIL
                     GPNSVLGASYTQKSWWQLSNSKESSPFRETNYEPQLFLGFATDYRFAGWTLRDVEMGY
                     NHDSNGRSDPTSRSWNRLYTRLMAENGNWLVEVKPWYVIGSTDDNPDITKYMGYYQLK
                     IGYHLGEAVLSAKGQYNWNTGYGGAEVGLSYPVTKHVRLYTQVYSGYGESLIDYNFNQ
                     TRVGVGVMLNDIF"
     gene            24515..24982
                     /locus_tag="OPV72_001474"
     CDS             24515..24982
                     /locus_tag="OPV72_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312777.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HCR9913824.1"
                     /translation="MSAVLTAEQALKLVGEMFVYHMPFNRALGLELERYEKAFAQLAF
                     NNQPMMVGNWAQSILHGGVIASALDVAAGLVCVGSTLTRHETISEDELRQRLSRMGTI
                     DLRVDYLRPGRGNRFTATSSLLRAGNKVAVARVELHNEDQLYIASATATYMVG"
     gene            25026..>25903
                     /gene="rarD"
                     /locus_tag="OPV72_001475"
     CDS             25026..>25903
                     /gene="rarD"
                     /locus_tag="OPV72_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter RarD"
                     /protein_id="HCR9913825.1"
                     /translation="MDAKQTRQGVLLALAAYFIWGIAPAYFKLIYYVPADEILTHRVI
                     WSFFFMVALLSVSRQWRQVKRLLKTPKKIFLLALSAVLVGGNWLLFIWAVNNHHMLEA
                     SLGYFINPLVNILLGMIFLGERFRRMQWLAVILAVCGVLVQLWTFGSLPIIALGLAFS
                     FAFYGLVRKKIAVEAQTGMLVETLWLLPVAAIYLFSIADSATSHMGQNALSLNLLLMA
                     AGVVTTIPLLCFTGAATRLRLSTLGFFQYIGPTLMFLLAVTFYGEVPGADKMVTFAFI
                     WVALAIFVMDAIYTQR"
BASE COUNT         6181 a         7221 c         6547 g         5954 t
ORIGIN      
        1 atacaaagcc tgtagatatt caatatcata aggttttata gttgacgatt aattaatatt
       61 taagaggact tttaggtagg ctaacgtaaa aagggacgct actgcgtccc ataaaatagt
      121 taaataaatg cgaacgcatc gccaaacaga cgatcttccc gcgcattacg ctcatgacag
      181 aacagatcgc gggcgatttt cgccatctca aaacgtccgg caatataaat atcgtgcccc
      241 gccagcgtac cataatcctg caataccgcc gtaagtaccg ttcctgtacg tccacgccag
      301 ccttcttccg gctgctcgac aacaggttca atacgcaaat taggatggtt aacagagagt
      361 gcttccagct cagagagatc atagaggtgc ttttcttcgc gaccgcccca gtaaatggta
      421 acatcgcggg ccgggttgcg cgctaacgcc gtcaacagga tggagcgtgc ataagaaaag
      481 cccgtaccgc ccgcgatcag aatcaacgga cgctcttcat cgtcacgtag ccaggcgtcg
      541 ccatgcggaa tatcgacgac gatttcccgg tctttcagaa ttcgatccat gaccgccatc
      601 gcatacagat tgagctcgga agcgccaatg tgtaattcaa taaacccttt ctcgtccggc
      661 gttgaggcca tcgaaaacgg gcgtttgtca cgctcgtcca ttacgaccat caaatactga
      721 ccagcgcgga atgaaaacgc cgcgtccggc actaaacgaa cccgatatac ggtatcggtg
      781 atagcttcta ccgaggtcac tttacagctt aaggttgtca tgcgctccct ctgtcgggtg
      841 tcgggtcaat accgacattt ttcaagccga gtcgccgcag cctgaaatgt cgatgtccgc
      901 tttcagttat ttaaagatag ccagctcatc ccaaatcgca tcaatacgcg cggtaacttc
      961 aggatcttta acaataggac gaccccactc gcgttgggtt tcgcccggcc atttgtttgt
     1021 ggcatccagc cccatttttg aacccagccc ggagaccggc gaggcaaaat ccaggtagtc
     1081 aatcggcgta ttttcaacca gcaccgtatc ccgcgcaggg tccatacggg tggtaatcgc
     1141 ccagatcaca tcattccagt cgcgtgcgtt aacgtcatca tcgcaaacga taacaaattt
     1201 cgtatacata aactggcgca aaaacgacca gacacccatc atgacgcgtt tcgcatgacc
     1261 agcgtactgc tttttcatcg tcactaccgc caggcggtaa gaacaccctt ccggcggcag
     1321 ataaaagtcg acgatttccg gaaactgttt ttgcagaata ggcacgaaga cttcattgag
     1381 cgccacccct aataccgcag gctcatcggg cggacgcccg gtataggtgg agtgatagat
     1441 ggcatcctca cgctgcgtaa tatgcgtgac ggtaaagacc ggaaagttat ccacttcatt
     1501 ataatagccc gtatgatcgc catacggtcc ttccggcgcc atctctcccg gctcaatgta
     1561 accttcaagg ataatctcgg cgctggcagg cacttccaga tcgttagaaa ggcatttaac
     1621 cacttcagtt ttcgtgccgc gcagcaggcc cgcaaaggca tactccgaca gagtatcggg
     1681 aacaggagtc acggcgccaa gtatcgtcgc cggatcggcg cccaatgcga cggagaccgg
     1741 gaaacgttca cccggacgcg cggctaacca ctcctgaaaa tccaacgcgc cgccgcggtg
     1801 agacagccag cgcataatca gcttattttt acctatcaac tgctgacgat aaatgcccag
     1861 gttttgccgt tctttgtgcg ggccacgcgt taccgtcagt ccccaggtaa tcagcggcgc
     1921 ggcgtcgtcc ggccaacagg tcatgacagg aagacgcgtt aaatcgacat catcgccaga
     1981 cgcgattttc tgctggcaag gcgcgccgcg taaccgtttc gtcggcatat tcagcacttg
     2041 cttaaactgc ggcagcttgt caaacagatc gcgaaagcct ttcggcggct caggttcttt
     2101 cagaaacgct aataatttac ccacttcccg taaggcggaa acatcatcct gccccatgcc
     2161 catcgccacg cgttttggcg tgccaaaaag gttgcacagc accggcatgg cgtaaccttt
     2221 aggattttca aacagcaacg ccggtccacc ggcacgcagc gtgcggtcag cgatttccgt
     2281 gatttccaga tgaggatcca caggtagcgt gatgcgtttt agttccccct gctgctcaag
     2341 tagcgtcagg aagtcgcgta aatcgtgata tttcatggcg tccattgtag cctcttggta
     2401 agcgcatcat tatacggcgt tcatcatcgg gatgctgtat ttttgttaaa ttagcgtgaa
     2461 ctctggcaac caacgctaat ccagatacgg cttaaaggat gaagtgtata attaacttcg
     2521 cgcatggctt ttgctatgct tgcgccccga acaagcggat aagagtcatt atgcaatcct
     2581 ggtatttact gtactgcaaa cgcgggcaac ttcagcgtgc tcaggaacac ctcgaaagac
     2641 aagcggtaag ttgcctgaca ccgatgatca ccctggaaaa aatggtacgc ggaaaacgta
     2701 ccttcgtcag cgaaccgctc tttcctaatt atctgttcgt tgaatttgat ccggaagtga
     2761 tacataccac tacaatcaac gccacgcgcg gcgtcagcca ttttgtgcgc tttggcgcgc
     2821 atcctgcgat cgtgccttcc agcgttattc atcagctttc tatctacaag cccgaaggcg
     2881 ttgtcgatcc tgaaaccccc tatcccggcg atagcgtcat catcacggaa ggcgcatttg
     2941 aagggctgaa agcgattttt accgaaccgg atggcgaaac gcgttcgatg ttactgctta
     3001 atttactcaa taaagaagtg aagcagagcg taaaaaacac cggttttcgc aagatttagc
     3061 gatcgttcag aatacgacct caaataaggt tctggcattg gcatctgtca tcgccgctaa
     3121 ccattgcgga tcttcaccac gccatagcgc tatgcgctcc aggatgtgag gcagatatgc
     3181 gggctcgttg cgtcgtgacg ttggtttcgg cgtaagatcg cggggcaaca gatacggcgc
     3241 gtcggtttct atcagtagct tttccgctgg aataaacggt aagagttcac gtagctcaag
     3301 cccgcgtcgt tcgtcgcaaa cccacccggt aataccgata tagagccctc tgtccacaca
     3361 ggcctgcatt tgctggcgtg aaccggtaaa gcagtgcagt attgcaccag gaagactatc
     3421 cagccaggga tcaagcaatg ccagaaatcg ctcatgcgcg tcccggcagt gcataaagat
     3481 tggcatctgc aattcggcgg caatttgtag ctgcgcctga aaggcacgct cctgctcctg
     3541 cggcgtggaa aaattgcgat tgaaatccag cccgcactca ccgatagcga cgacttccgg
     3601 ctggttcgcc agcgcaataa tggcgtcttc agacgcagat gaccactgac tgctgtcatg
     3661 gggatggacg ccagccgtcg accaacaatg ggggtagcgc cgcgccagtt ttaacgcctg
     3721 ctgactttca tggatgttcg ttccggtcag tagcatacct tttactcctg ccgcaaacgc
     3781 acgggcgacc acatcatcac gatcttttgc aaactggcta ctggttaaat taacgccaat
     3841 atcaaacatg cttgccccca tatgacaacc gccctggcgg gcggttgtgt ttagtcttca
     3901 gtgtgctcgg ccttttcggt ctcggcctcg ttatcttcgt cgcgcgtccg tcgcttaccg
     3961 acataaaagc gtgagcagaa aacgccaatt tcaaacaggc agtacatcgg tatcgccagc
     4021 aacgtttgcg agaagacatc tggcggcgta agcagcatcc ccacaatgaa tgccccgacc
     4081 aggatataag gccgtttttt acgcaaatct tctggcgtgg tgatgcccat ccagcacagc
     4141 aacacaatcg ccaccggcac ctcaaaggct acgccaaagg ccataaaaag cgccatgaca
     4201 aagctcagat agctggcgat atctgtcgaa acctgtaccc cttccggcgc cgtatgcgtc
     4261 aggaaaccaa aggccaaagg gaatacgaca aaataggcga aggccatacc aatgtaaaaa
     4321 agcagcgaac tggataccag cagcggtacg accagacgac gctcgtgttt atacagcgcc
     4381 ggggcgataa aggcccaaac ctggtacaaa atgacaggcg cggataagat caaagacacc
     4441 atgaaggtga gtttgatagg cgtaaaaaac ggcgacgcca catccgtcgc aatcattgtc
     4501 gccccttgcg gcatctgttt tatcagcggt gcggcgacta aatgataaat atcattggcg
     4561 aaataaatta acgccagaaa aatcagaagt actgcgacga tgcagtttag caggcgctta
     4621 cgcaactcga tcagatgcgt gataagcggt tgagtatctt ctacagccat gtttacggtt
     4681 tatcactcga cgagggggaa gattcgacaa caggcgcagc ggatttcttc tcggcgtcta
     4741 tcgcggctac ggaagcggtt tccgtcgact caggcacgtt agctttaacg ggctccggct
     4801 tttgttccgg cgcgctcgcc tgtgtttcag cggcggcagg ggtgacgccc tcatgctgcg
     4861 tttcgttccc ttttaccacc ggattatgga tggtatgcgc ttcatcgctc gcttgttcgg
     4921 gatcgttagc gctgtaggtg cgtttcatcg actccgccgc ctgacgcagt tcatccatag
     4981 atgctttcag ttcgggagtc agattttcca ggctcgcctt ttcgactttt ttcagactgt
     5041 cctggaactc ctgaagtttc agttcctgag tcagttcatt ctgaaccgtt gtcgcaaggg
     5101 agcgcaacgc gcgaatccag cccgctaccg tttttaccgc tactggcaat cgttgcggcc
     5161 ccaacacaat gaggccgata acgaacacta acagcagttc gctaaaaccg atatcaaaca
     5221 cggattatac ctgctcttta tcttggcttt tagcgtcttc ctttttcgct tcgccttgct
     5281 tatccgcgat agatttagcg gtaaaatcag cgtcctgact ggttttatcc tgtttggcat
     5341 catcatcgct catggccttt ttaaagcctt tgatagacgc gccaagatcg gaaccgatgg
     5401 aaccgagttt tttggtgccg aacagcagta cgacgataac ggcaacaatc aacaactgcc
     5461 aaatactgat accacccata catgttcctc tgtgatagat gatgaattat tagggccgca
     5521 ttatacacat tatccttcgc gctgcctctt tgttagccgc tttcgcccgt cctattcaca
     5581 tacttttaca tacgaccggg acgacattga cttgcggcct gagtattgcc tcgagtgata
     5641 atatgtacct gcgtgacaca accggcgttg agcgataaaa aatctcaacg agttttacgc
     5701 cagccaacca gccagaccac tacgccgccg accatgagcc agccaggcat caatccccat
     5761 tcagggcggt tgacgagtaa gaatgacccg ctcagtaaca gcgttgcgcc aattcccaat
     5821 aaataacgag actgactttg gcgcacatgg tttacctgta actcgcgcgc aatcttatca
     5881 acactgtgct gtaaatattt gccctggcgc aaactgtcgt acaccagttc aggtatttct
     5941 ggcatttttt cgacccagaa cggcgctttt tctttaagag cccgcgtgag agccggaata
     6001 cccacctgat ctttgatcca ggactcaaga aacggcttcg ccgttttcca caaatcaagc
     6061 tgaggataaa gttgccgccc aaccccttca acatacaata atgttttctg caacaacacc
     6121 agttgcggct ggacttccat gttaaatcga cgcgctgtat tgaaaaggtt taacaacaca
     6181 tgaccaaacg agatttccgc gagcggcttt tcaaaaatag gttcacagac ggtgcggatg
     6241 gcaaactcaa aatcttcaac gttggtatct ggcggaaccc aacctgaatc gacatgcagc
     6301 tccgccacct ttcggtaatc gcgattaaaa aacgcgataa agttttcagc cagataacgc
     6361 ttatcttctt tgtttagcga cccgacgata ccgcagtcaa tgccgatata ttgcggattt
     6421 tcagggtgtt catgactgac aaaaatattt cccggatgca tgtccgcatg gaaaaagctg
     6481 tcgcggaaaa cctgggtgaa gaaaacttta actccgcgtt ccgccagcag tttcatgttg
     6541 gtgccgttct tttccagcgc cgccacatcc gaaaccggaa tgccatatat ccgctccatc
     6601 accatcatgt tctggctaca gtaatcggag tacacctccg ggatatacag catgggacta
     6661 ttttcaaaat tgcgacgtaa ctgaatcgcg ttggccgatt cccgcagcag attcagctca
     6721 tcgatcagcg ttttctcata ctcacgcacc acttccgtcg ggcgcagacg acgcccatcc
     6781 ggcaacaggc gtggtaccca gcgagcaagg cgataaatca gtttcaggtc tgcctgaatt
     6841 accggcaaaa tatccgggcg aatgacctta ataaccactt ctttaccgtt tgatttcaat
     6901 cgcgcggtat gtacctgggc gattgacgcc gacgctaaag gctggatatc aaagtcgtca
     6961 aaccaggctt cgacaggtag cccccccatc gcctcttcaa tctgggcttt cgccagccga
     7021 ccatcgaatg gcgcgacttt atcctggagc aaagcgagct gatcggcgat ttgcggcggg
     7081 aacaggtcac ggcgcgtgga gagcatctga ccaaatttga tccagaccgg tcccagctct
     7141 tgcaacgcca gtcttaatcg ttcacccagc aatttatctt tatgccggtt tggcatccag
     7201 aacagcgaat agcgccataa tcggagtggc agtgtaagac gcattcgggg gatgagttca
     7261 tcaaggccgt agcttagaaa cgtgcggatg atgaaatata ggcgccgtac ttcacctggc
     7321 gtcatttggc ccccagtttt tccagccgtg tggtcagaga atctacggcg cgctcaacag
     7381 ccgcggtttc ttcggcaaac catgcgactt ccagcgggcc aggcgccata cgccactctt
     7441 cagtgatcgc ttcagcggca taacgctgct ggcgttgaaa cccgtggcgc aggaatttag
     7501 ccccgccacg cacgacctta ccgatacttt ccgccgcaat atcacccgtg tatggcgcca
     7561 acagctccgc aggatcgaat tcggcgagat cggcgagcgc cacaaaattt tgcacgacct
     7621 gaatatcgcc ctgcacttcc agttcgccgc tgcgaataag cgcggccaac tgctgacgat
     7681 cgcgtagttt tggcaaaacg ctagcttgag tgattaccgt acagtccgct tcgccttccc
     7741 atgcccccag cacatcaacc tggcgttcac tgaataccag gactaatggc gtcgaaaatc
     7801 cctttagttt cacacacagt acttttccct gtaagcgcgt tctggctgat ttcagcgctg
     7861 gcgaacgata cagaaacgta ttgaggagac cttcaattcc tgcggtcact aagggtttaa
     7921 aaggcattcc accctcctag aatttataac cacggtgcaa tgccacaacg cccgccgtca
     7981 gattgtaata atccacgctc tcaaatccgg cgtcctgcat catggctttt aaggtatcct
     8041 gatcgggatg catacggatg gattccgcga gataccgata gctatccgca tcgttcgcga
     8101 ccatcgagcc aatacgcggt aaaatatgga aagaataggc gtcatacgct ttactcagcg
     8161 gctcaatgat aggcttggaa aattcaagca ccagtaaacg tccgccgggt ttcaacacac
     8221 ggaacattga ccgcagcgct ttttcttttt ccgttacatt gcgcaaacca aacgaaatgg
     8281 taatgcaatc aaacgtatta tcagggaaag gcagagcttc ggcattcgcc tgcacatact
     8341 ctacgttgcc gatcacgccg atattacgca gcttctcacg ccccattttg agcatagaat
     8401 cattaatatc cgccaggata actttgccag tttccccgac catacgtgaa aatttcgcgg
     8461 taagatcgcc cgtcccgccc gctaaatcga gaacggtttg tccacgacgc acgccactgc
     8521 aatcaatggt gaagcgcttc cacaaacgat gaatgccaaa tgacattaaa tcattcatca
     8581 catcgtactt tgacgccaca gaatgaaaaa cgtgggccac catgtcagct ttctgctctt
     8641 tagcgacggt ctgaaagcca aagtgcgtcg tttcttgtga atcttccacc atctcagtgc
     8701 ctgcttatcg ataaaaatgt tcaagaagtg taacagattg ggccaatttg ccctactctg
     8761 cgccaggact aaactactcc gtatgggtta acttaactgc tgcttcaccc gttcatcatt
     8821 gggataatgt tcatcctgcc gcccttcagg gatcgatcgt aaacgatatt cttcatcttg
     8881 cgtaacggcc tgttccgcta aatccggatt aatctcgcgt ttgatttcca cgcctagccc
     8941 ccggaaggcc tccgcctgcg ccaaaacgtt gccacgcccc gacgcaagtt ttttcatcgc
     9001 ctggcggtag ttatcctgcg ctttatccag actctgaccg atcgctgaca tatcatcaac
     9061 gaacaaccgc attttatcgt agagcttact ggctctgtct gcgatgtgct gcgcattgcg
     9121 gctctggtgt tcatagcgcc acaggttggc gattgtccgt aacgccacca gcagcgtcgt
     9181 ggggcttacc agcataatgt tatttttcag cgcctcggtt atcagttcgg gctgtttatc
     9241 taacgccagc aggaaagcgg gttctacggg gataaacatc agaacatagt ccagcgagcg
     9301 gaggccggga agctgctggt agtctttacg ccccagtaag cgaatatgat tgcgcaccga
     9361 ggcgatgtgc tcttgtaaag cggcctcgcg cgtatagtca tcttcagcgt taaagtaacg
     9421 ctcgtaggcg actaacgtca ttttagcgtc gatgaccaca tctttgccct gcggcaagcg
     9481 gacgatgaca tccggctgca tccgcgagcg cgcatcgttc tcaatactga cctgggtttc
     9541 gtattcgtag ccttcacgca gtccggatgc ctccagcacc cgcgccagca caacttcgcc
     9601 ccagtttcct tgtgccttat tgtccccttt cagggcgcgc gtcaggttga tcgcttcctg
     9661 cgccatttgc gcgttaagct gctgcaaatt acgaatttcg tgcgccagcg tatgccgctc
     9721 ctgcgcttct ttgccaaaac tctcctgaac ctggcggcga aaaccgtcca gttgctcacg
     9781 cagcggcgtc agcaggctat tcaggctttg tcggttttgt tcgtctacgc gacgattact
     9841 gtgttcaaag atacggttcg ccagattttc aaactgctcg cttaaacgct gttcgctgtt
     9901 gatcatctga cggattttgt cttccgcgtg ttgttgagtc gcttccagac gagtcgtgac
     9961 ttcacgcaga tcggcttcca gagaggtatt aatactgtgc aggctacgca gttcgttatt
    10021 aagtaactcg cattcactgc gccagtgcgc ttcttgcgct aattgctgcc gggccgcgct
    10081 aagttcaata tccagctcac gccgttcttc gataagatcg gcgcggattt gatcggcgtg
    10141 cgctttcgtc gccagccagc caatcaccgc cccagccgcc agcgccacga cggcgcttat
    10201 cataagagta atatccacaa cacctctcct ggaaccacac tgtcctgcac aaaatagaat
    10261 tgtgctgtat aaacgtccag tttaaaaggg atttcctgcg aggcgccacg caaaaagaaa
    10321 aggccgaacg cgtcggcctt tgcaaaagag aggagaatta cagcagacga cgggccgctt
    10381 ccacgacaat tttcaccgcg tggctttcag tttgtttcat cgtttccgca ttcggaatct
    10441 cttgttgggt acggttaacg ataacgcccg ccaccatacc tgcgcgtaaa ccctggcttg
    10501 cgcacatggt taacagcgta gcggattcca tttcgtagtt catcacgccc attgcctgcc
    10561 actcttccat agagcctttg aagcgacgaa caacgcggcc agaataggtg tcgtaacgtt
    10621 cctgacccgg atagaaagtg tcggaagagg cggttacgcc aacgtgagtc gtggcgccaa
    10681 tcgatttcgc ggcttcaacc agcgcggtgg tgcaggcaaa gtcggcaacc gccgggaatt
    10741 ccatcggcgc aaaatgcagg cttgccccat ccagacgtac ggatgcggtc gttaccagaa
    10801 cgtcgccgac gttgatgtgc ggctgaatag cccccgtggt gccgatacgc aagaaggtac
    10861 gaatacccag ttgcgccagt tcttccacgg caatagaggt agacgggccg ccgataccgg
    10921 tagagcaaac gataactgct ttaccatcca gctcagcgcg ccaggaggtg aattcgcggt
    10981 gagatgccag cttaaccggc ttatccatca gcgcggcgat cttttccaca cgctcaggat
    11041 cgccagggac gatggcgagc tgggcccctt gtaaatcgtt tttggtgagg ccgagatgaa
    11101 aaacatcaga cttggacata taaaactcct ctgtgaatcg ggtttgtcag aagaagcaaa
    11161 aagacacttt acctaaggca taaagatatt ttcgtgacag ccatcactat ggcgtaaaac
    11221 aattgcactc gtttaccatt aaaaagtgat gtgcatcaca ataaataatc aatatcgcca
    11281 agcattgcac aaaagatagc cgctttaagg caatgtggtt tgttacacac tgtctatagt
    11341 taagattgcg ctatttttta agggtacgga gaataccatg acaacgacac atccatccgg
    11401 ctttgcacct gcagcttccc cacttgcccc tacgatgatt catacacctg atggggccat
    11461 tagcgcgggg ataacgtcga tcccctctca gggcgacgat atgccagcct attacgccag
    11521 accaaaggca agcgacggcg cgctgcctgt ggtcattgtg gtacaggaaa tttttggcgt
    11581 acatgaacac attcgcgata tttgccgacg actggcgctg gaaggctatc tcgctatcgc
    11641 gccggagctc tatttccgcg aaggcgaccc caatgatttc gccgatatac ccacattatt
    11701 gagcgggctg gtggctaaag tacccgattc gcaagtcctt gccgacctgg atcacgtcgc
    11761 cagttgggct tcgcgcaacg gcggggatgc gcatcggctg atgatcaccg gtttttgttg
    11821 gggaggccgg attacctggc tatacgccgc gcacaaccca cagttaaaag cagcggtagc
    11881 gtggtacggc aagctggtgg gcgacacgtc actcaattcg ccgaagcatc ccgttgatat
    11941 cgccaccgat cttaacgcgc cggtactggg tttatacggc gggcaggata ccagtattcc
    12001 acaggagagc gtggaaacca tgcgtcaggc gctacgcgcc gctaatgcga aggcggaaat
    12061 cgtggtctat cccgatgcag ggcacgcgtt taatgccgat tatcgtccgg gctaccacga
    12121 agcctcagcg aaagacggct ggcaaagaat gttggaatgg ttcgcgcagt acggtgggaa
    12181 aaaaggctaa ccacagcgca ttacgatgtt tgttgggcct acgagaccgg agtcggtgta
    12241 ggctcaacaa atcgtcatcg ccacgttagc tatgctttac cacagcattt ttatattttt
    12301 tgccgctgcc gcagggacag agatggttac gactgacggc tcctgtgtct ttacgcgcgt
    12361 cctgcgccag ccagcgcatg atcgatgcca tcggatagcc ttgcgccagc agctcccgcc
    12421 agacattcat atacggcgta acgtgctgga aaaaatgttt atagcccgta cacaagtaat
    12481 tatgcgcagg atgaccggac ggcgagacgg caaagcgatg cttcggacag ccgccatgac
    12541 acgcaaagcg gtagtcacag cgacgacaat cggcggtcag ggtctcccgc ttggcctcgc
    12601 caaacgcaat agcccgctcg ctattattta aggttttgat gctgtgctgg tggatattcc
    12661 ccagcagatg ctccgggtag acaaagtggt cacagttgta gagatcgccg ttcgactcca
    12721 acgcgaaggc atgtccacaa gtctcggaat gtacacacag taccggctgc tgcgccgtcc
    12781 aggcggctaa cgccacgtca aacatctgca catagacgcg gtctacgtcg cgacgaaccc
    12841 agatatcaaa gatctggttg agaaattcgc catattgcca cgacggtacc gtccatggcg
    12901 ccagctttgc cgcgctttcg ccgggcatca ccagattaag taccgatgag ttatcggtgc
    12961 tcattcgctc taccagcggg ataaactgaa taaaacgcga tcccgccgcc agaagaaatt
    13021 cgtagacgtc tgctgcatga ccgacgttat gttttcccac gacggttaag gtattaaagt
    13081 caacatggtg cgctttaagc cgcgccatgg ctgcgacgac ctgttcatga gttccttttc
    13141 cagcgcgatt aagccgatag tggttgtgta acgacgccgg accgtcgata gagagaccga
    13201 tgagaaaatg ctgttcagcg aaaaagcgcg cccactcgtc attcaccagg atgccgttcg
    13261 tctgtaacgc atgagtgatt tttcgcccat cgccgtactt ttcacacaat gcgacaaccc
    13321 ggcggaaaaa tggcagcccc atcatggtcg gttcgccgca ctgccaggca aagtcaatgc
    13381 ggtcgccact ctgcgcggca atatgctggc gtataaactg ttccagcgtc tcgtccgaca
    13441 ttcgccagtt tttattgcgt tccgggtaca gcgcctcttt ttcaagatag aagcaatatg
    13501 tgcaatcaat attgcagatc gcgccgccgg gtttggccat tacgtgacaa cctgctaccg
    13561 ccatgtcaga catctccgtt aaaaaataag gttcaccagc gccatgagac aatgcgacgt
    13621 ttatcgtcgc cagggaacat aacagaatgg aaaacctcgt tttgtgctat gagagcgctg
    13681 ggcgatcatg acaggaaaaa cgatctgcga ggcaataaaa tccgccgcgc tgcttccggg
    13741 gacgctatcc gcctggttgt cattcatacg gagaaccttt ttattatcaa gatcgccaaa
    13801 tagccagatc ctgaaaaaga cagcgcggaa aataagaaaa agggaaatga gaagaaagag
    13861 gcgctgttaa tcaggtcaga cacgggcgct acccgtcaaa gggtagcgcc gcattgctgc
    13921 cggataaacg cagcggtcag gatgggttat ttcgcctgac gcagattgtg cgccgctttg
    13981 accatgttcg ctaacgccgc gcgggtttcc ggccaaccgc gagttttcag accgcagtcc
    14041 ggattcaccc acaggcgttg tgccggaata cgttgtgccg ccttcttcag cagggcttca
    14101 atccactcga cgctcggcac gttcggcgag tgaatatcgt acacgcccgg cccgatttcg
    14161 ttcgggtagt cgaacgcttc gaacgactcc agcaactcca tatccgagcg ggaggtctca
    14221 atggtgatca catccgcgtc cagcgcggcg atcgaatcca taatgtcgtt gaactcgcag
    14281 taacacatgt gggtgtggat ctgggtttca tccttcgcca ccgccgcgtt gatgcggaag
    14341 gcttccacac cccattccag ataggcgtcc cagtcgctgc gacgcagcgg taaaccttca
    14401 cgcagcgccg gttcgtcaat ctgaataatc ccgatccccg ccgcctccag atccgcgact
    14461 tcatcacgca gcgccagcgc aatctgtttc gcaatcgttt cgcgggtcac gtcttcgcgg
    14521 gggaatgacc agcaaagaat agtcaccggg ccggtcaaca tcccttttac cggcttgtcg
    14581 gtcagcgact gggcatattt cgcccactcc acggtaatcg gtgccggacg gctgatatcg
    14641 ccaatcacta ccggcggttt cacacagcgg gagccatagc tttgcaccca accattctgg
    14701 gtaaagacga agccgtccag atgctcgccg aagtattcca ccatgtcgtt tcgctcggct
    14761 tcgccgtgta ccagcacatc cagccctaaa cgctcctgct cgatgatagc ctgtttgata
    14821 tgttcggcga tgccggtgcg gtagttgttc gcgtcgaggt tgcccttttt gaagtccaga
    14881 cgcaggccgc gaatttccgt ggtttgcgga aacgaaccga tagtcgtcgt cggccaggcg
    14941 ggaagtttaa agcgggcgcg ttgcgcttca gcgcgcacct catacggatt ctcacgctgg
    15001 ctgtcctgcg cggtgatcgc cgccaggcgt ttttctactg cggcattatg tacgcgatgg
    15061 gagtgacgac gagcctgaat cggtacgctc cattcctcaa gcgccgccgt ttcgccgctg
    15121 ttcagcgcat cgcgcagcaa cgccagttca ccgcattttt gcagcgcaaa ggcaaaccag
    15181 ctttttactt ccgtatccag acgcgtttcg acgctgagat cgatcgggct gtgcagtaaa
    15241 gagcaggagg atgctaccca cagcgcgcgt ttgcccacaa tggcgttaat ctgcgcgtat
    15301 ttttcggtca aatcggcgcg ccagacatta cgcccgttaa tcaagcctgc ggagagcagc
    15361 cagtcgaccg gcagacgttg atgcagttcc actacatcat ctttgccatg aatgaggtca
    15421 acatgtagcc cctgtaccgg tagcacgata atagtgtcca ggtttggcgt cacgccttca
    15481 aaataggtcg tcagcaacag cttcacctgg ccggcgagcg cgtcgtaagc cggtttgaag
    15541 gcatccagcc acgcctgcgg cagttccagc accagtgctg gctcatcaat ttggacccac
    15601 tcaacaccac gcttcgccag ctcagccagc acgtgctgat acaccggcaa aatgtctttc
    15661 agcaacgtca ggcggtcaaa cggctcgcct ttcactttac ccagccacag atacgtgaca
    15721 ggccccagca gtacgggttt gatcttatgc cccagcgcca gcgcttcgtc cacttcctcc
    15781 agcaactgtg tccaggtaag cctgaactgc tggcctttgc tgaactccgg tactatgtag
    15841 tgatagttag tattaaacca tttggtcatt tccgctgccg ccgccggttc gccggttggc
    15901 gcgcgaccac ggccaatgcg gaacagagtg tcgatgtcca cggaaccgtc gttgttctga
    15961 tgacgagccg gcacattgcc taacagcagg ctggtggtca gaacatggtc gtaccaggca
    16021 aagtcgccta ccggtaacag gtcaataccc gcttgtttct gctgctccca gtgacgcgcg
    16081 cgcagttcgc ggcccaccgc cagtaacgct tcacgcgttg tgttccccgc ccagtagctc
    16141 tcttgcgctt ttttcaactc gcgacgcagg ccaacgcgag gaaaaccgag ggtatgagtc
    16201 aatattgtca ttttacttcc tctcttattt tattgaatct gaaagtaaaa ctctaaatag
    16261 ttcggcttgc aggaaggcgg cgacacagcg catccccagg agcttactga agtaagtgac
    16321 tggggtaagc aaggaagcca acgcatctgc aagtcgaaat atgacgagtt ttagacgtct
    16381 ggatgtttac acatccataa tgtaaaggta ctgtatattc ctcaagcgca atttgttcat
    16441 ggcgaagtga aggactttca tgatcgaaat taaacatctg aaaacactcc aggcattgcg
    16501 gaatagtgga tcgctggctg ctgctgctgc ggtgctgcac cagactcaat ccgctctgtc
    16561 tcatcagttc agcgatctgg aacaacgcct tggcttccgc ctgttcgtgc gtaaaagcca
    16621 gccgctgcgc tttacgccgc agggggaagt tctgctgcaa ctggcaaacc aggtgctgcc
    16681 gcaaatcagc cgtgcgctgc aggcgtgcaa cgaaccgcag caaactcgtc tgcgcatcgc
    16741 tattgaatgt catagctgta ttcagtggct gaccccggcg ctggaaaact tccgtgcaag
    16801 ctggccgcag gtagaaatgg atttcacatc cggcgtcact tttgatccgc aaccggcctt
    16861 gcaacaaggc gagctggatt tggtgatgac gtcggatatt ttgccgcgca gcgggctgca
    16921 ttattcgccg atgtttgatt ttgaagtccg actggtgctg gcgcccgacc atccgctggc
    16981 cagcaaaacg cagattacgc cggaagattt agccagcgaa acgctgttga tttacccggt
    17041 gcagcgcagc cggctggatg tctggcgaca tttcctgcaa ccggcgggta tcagtccgct
    17101 gctgaaaagc gtggataata cgctactgct gattcagatg gtggcggcca gaatgggtat
    17161 tgccgccctg ccgcactggg tggtggaaag cgttgagcgc cagggtctgg tggtgaccaa
    17221 aaccctgggc gatggtctgt ggagccgcct gtatgccgcc gtgcgcgacg gcgaccagcg
    17281 tcaggcggtg accgaggcgt ttattcgctc gacgcgggat cacgcctgcg atcatctgcc
    17341 gtttgtgcgg agcgcggagc gacccatttt cgatgcaccc acagcgaagc caggatcaca
    17401 gccgcgcctg taataaagct tggccagtgg ggctgctgat gccagatggc aagattaacc
    17461 agcagtcctg cgggaacatg catattattc atgataccca gcgtcccggc gtctacctgg
    17521 gtagcgccat agttccacat aaagtagcca atgccggacg ccaccacgcc gagaaacacc
    17581 agaatgctcc attgcagcgt ggtttccggc agcttttgcg cgttccccaa cagcgaccac
    17641 gccaccgccg ccaccaaaaa cgcccccaga tagaaccacg caaaggcgtt gtgctgcggc
    17701 atgggacggg tctccatcag acgtttatac cccaccattc cgatagcgaa actgatatta
    17761 gaaagctgca ccaggagcaa accgacccaa aaatggtcgg tcacgcgatc gtagcgaata
    17821 atcccggcgc caatcaccgc cagcaacgcg ctaaatgcat agccccagcg caaacgacgc
    17881 tgactcatca catcgtaaat cagcgtgata tagagcggcg tcaaaacggt aaacagcagc
    17941 agttcggata cggtcaggta gaggtaagca tggaagctca acatatacat gatgccaagc
    18001 tgcatcgccc ccaccagcat atacaggctg atggttttta ggttgtgccc gcgagtacgc
    18061 aaaaacggca gaaaaacgag cgccgccagc ccaacgcgta tcagcaccgc gaaatagcta
    18121 tcgacatgcc cggcaagata ctcgccaaat agactaaagg agaaagccca caggatagtg
    18181 gtgatgatga gtagcgccac aatggatgtc tcttaaaaca gggaacaccc attgtagcgg
    18241 agagtgaggt tgacaactgg tcaactaaca aacaatcaca tcagcgtaag aaaagatcgc
    18301 gcaggtaatg cggcacggcg ttatccgcgt tgatgccgat cacctcaagt tcgggataca
    18361 ggtctttcag acgctggtgc gcattgccca tgatgcagcc tttgcccgcc atcgtgagca
    18421 tttcagcgtc gttcattccg tcgccaaagg cgatacactc tttcaggctg taccccatcg
    18481 cctgagcgac cgcttccagc gcatgacctt tcgacactcc gcccgccatc acttccagac
    18541 aggttagcgt agagaagctc acgtttaccc gatcgcccca gcgcgcgtta atcgcctgct
    18601 ccagcggcaa caacttttca tgagtgtcgc tggtgaaaaa cactttgctg acgccctccg
    18661 gctccagcag cgcaggctca aacagcgaat agttaaatac cgcctctttg aaaaaacgca
    18721 tttcatcggg gcgatgacga ttcataaacc attcgtcgtc gcgataaacg ttagtcacga
    18781 tgtccgggtt cgcattcacc acgccgaaca ggtcgctggc aatgtcgctg tccagattat
    18841 gcgtaaaaac caaattcccg tcggtatcgt gcactcgcgc gccgttggag gtgatcatgt
    18901 aagacttgat ttcaagatta tcgcggattt gccctacatc gacatgatga cgaccagtgg
    18961 caaagacaaa atggatgccg cgtgcggtca acagcttcag agtctctttg gcataagggg
    19021 acaacgtatg gtcgggggag agcagcgtgc catctaaatc agacgcaaca acctgataca
    19081 taataaaatt taacctctaa gcaaagcgat ttccgctgga taaattaggc ttgttgaaaa
    19141 attcaacaat ggcgttaagc gcgactgagc gcatggcgtc cttttcaaaa aggatctcat
    19201 ggtacgcgcc tttgataacc agcggttttc ccccttcaca agggtatccc gccgcggcgc
    19261 gaatttcaca aaaacgatcg tgggtgcggt tatccactac ccgctcttct tccgcctgaa
    19321 tcagtagcgt aggcgtcgtg tcatcgctcg ccccagccag tacctgctca cccgccagaa
    19381 tgccttcgcg tacccaatgc caggtggggc cgccaacgcg cagctgcggc tcgtcggcat
    19441 aaaatcgtaa gttgcgctga taacgctggc ggctgtgggt cagcgcattc atcccaaacg
    19501 gcaacgcccg ccactgaccg gtaccaatag cgtaatcttc acggatacgc tgatgccctt
    19561 cggcccagtc gagaatatgg cgcaccataa aggaaggcaa gcgtatcaca ataccaaaca
    19621 tcggcgcggt gagcgcaata gcgtcgcacc gcacacgatg gcgttgcagg aacagggtgg
    19681 ctatcgcgcc ccccattgag tgcgccagga tataacgctt acgccacgac cccggctcaa
    19741 tttcctgctg ccagaacgcc gctaagtcct caacataatc gttaaaatga tcgacatgac
    19801 cccgatgcgg gtccgataac atccgcccgg agcgcccttg accacggtgg tcgatgatga
    19861 agatatcaaa accgagatga aaaaggtcat acgccagttc agcgtatttt acataactct
    19921 caatgcggcc aggacaaatg acgatcgtcc gatcgttgga gtcattccga aaacggacaa
    19981 agcgcaccgg aatgttatcc acgccgataa actccgcctc ttcccgctga cgccaaaaat
    20041 cggtcagcgg ccccatagca aaagcggcaa acgcattttc tcttgtttcc cagtcatttt
    20101 gctgctgaaa catcgggttt tcggcctcgt ttaccaggta aaatcgtttt ttgcgtcgtg
    20161 cctgacacaa cacagcggca gtagcgtatt gtggcacaaa aacagacaac caaggagttt
    20221 cgcatgacct ttgaatggtg gttcgcctat ctactgacct caactctgtt gagtctttct
    20281 ccgggttcag gcgccatcaa taccatgacg acgtctatca accatggata tcgtggcgca
    20341 gcggcttcta tcgccgggct ccagaccggg ctggggatac atatcgtact ggtgggcgtc
    20401 ggactgggta cgctcttttc gcgctcgctc atcgcttttg aaattctgaa atgggctggc
    20461 gcggcttatc ttatctggct gggtatccag caatggcgcg ccgcaggcgc tatcgatctg
    20521 catactctcg cccagacgca atcgcggggt cggctgttca aacgggcgat atttgtcaat
    20581 ctaaccaatc ccaaaagtat tgtctttctt gccgccctgt ttccgcaatt catcatgccg
    20641 cagcaaccgc aactggcgca gtacctcatt ctcggcgtca ccacgattgt ggtggatatg
    20701 attgtgatga ccggttacgc cacgctggcg cagcgcattg ccgcctggat taaaggacca
    20761 aagcagatga aggcgctgaa taaagcgttt ggttcgttgt ttatgctggt aggcgcgctc
    20821 ctggcgtcgg caagacacgc gtgatagtcg tgccggatga tgtttatccg gcccggaggt
    20881 aaattaacgc gaaataatca ggtgaatacc aaagcccgca aacagagcgc cggcaaagcc
    20941 atcaatccat ttcgccagac gctgatagcc acggcgcatt ttcggcagcg cgaacaggct
    21001 ggcgactacg gtaaaccagg ccagcgtttc cagggtaatt aacgcgaaaa taccccagcg
    21061 cgccgcagcg ccgacgttat cgccgacaaa cagtgaaaaa acggaaccaa aatagataat
    21121 cgctttcgga ttcgacagat tggtcagcag ccctttgaga aaactgcgcc cgctctgcgc
    21181 cagttcaatg tgcggagaag acgccgccgc atcctgtttt ttcagcgcgc cgcgcagcat
    21241 ctgatagccc atccagcaca ggtacaggcc gccgcctacc ataatgatcg tatgcagcca
    21301 ggccattttt tcgatgatga gatgcaggcc aagcagcgcc acgcccgccc ataccatcac
    21361 gccgcaggtg atgcccagta cgcccatcat cgcttcttta cgcgaacggc tgacggcagt
    21421 ttgagacacg aagaaaaaat cggggccagg gctcattagc gcaacgatgt gcaccattgc
    21481 cacggtgaaa aatagcatca acataaaaat ggctcgcggg gaaatagttc agtgagtcac
    21541 catcctggca cttttttgcc gggctgacta ctcttcgtca tcaccatcga catgcgcgcg
    21601 gatgagcgcc atgaattctt tcccgaagcg ctccagtttg cgcatcccaa ccccgttaac
    21661 gcttaacatc tcgctggcgg aaaccggcat ctgttccgcc atttctatca acgtggcgtc
    21721 gttaaagacc acatacggcg ggatattctc ttcatcagcg atagctttac gcagcttgcg
    21781 caacttagcg aacaatttgc gatcgtaatt accgccgaac gatttctgca tcacgcgggg
    21841 tttgagggcg acaatgcgcg gcaccgcaag ctttagcgga acgtctccac ggagtaccgg
    21901 acgcgcggca tccgtcaact gtaatgcgga gtgctgcgca atattttgca ttaccagccc
    21961 cagatgaatg agctggcgaa tcacgctcac ccagtgctca tggctctttt cgcgtcccat
    22021 gccataaacc ttgagtttgt catgaccgaa atcgcggatg cgttggttat tcgcgccgcg
    22081 gatcacctcg acaacgtagc ccatgccaaa acgctggtta acccgaccaa tggtagaaag
    22141 cgcaatctgg gcatcgttta agccatcata ttgtttgggc ggatcgagac agatatcgca
    22201 gttgccgcac ggttcttgtc ggccttcgcc aaagtaatta agcaatacca ggcggcggca
    22261 ggtttgcgct tcggcaaaag cgcccatcgc attcagctta tgccgttcaa tatcctgaag
    22321 ctgtccggct ggtttctctt ccagacaacg acgtagccag gccatatcag ccggatcgta
    22381 aaatagcatg gcttccgcag gcagtccgtc gcgcccggcg cggcccgttt cctgatagta
    22441 ggattcaata ttacgcggga tatcgaaatg cacgacgaaa cgtacgttag gtttgtttat
    22501 gcccattcca aaagcgacgg tcgccaccac gatttgcaga tcgtcgcgct gaaatttttc
    22561 ctgcacatcg gcgcgaatag cgttttccag ccccgcatga taggccgccg cgctaatgcc
    22621 gcgactttgc aagcgcgcgg cggtatcttc cactttcgcc cgactgttgc agtagatgat
    22681 acccgatttg ccgcgttgct cctgaacata gcgcattagc tggtcgagcg gcttaaactt
    22741 ctccatcagc atgtagcgga tattcggtcg gtcaaagcta ctgatctgga ttaacggatc
    22801 gttaagccca agcagacgaa taatatcctg gcgcgtggtg tcgtcggcgg tggcggtcaa
    22861 tgccataaac ggcaaagcgg gaaaacgctg gcgaagctga ccgagagccg catattccgg
    22921 acggaaatca tgtccccatt gcgagataca gtgcgcttca tccaccgcca gcaataccgg
    22981 attccagtgc gccagatgat caagaaagtt gtccagcatc aggcgttccg gcgcaatata
    23041 cagcagacga atctgtccgg tacggcaccc cgccatcacc tcaagctgct gctcgcggct
    23101 ttgagtggag ttcagacagg ccgccgccac cccgttcgcc agtagctgat cgacctggtc
    23161 tttcatcaac gagatcaggg gcgaaacgac gacggtcaat ccgtccagca acaacgcggg
    23221 gatttgatag cacagagatt tgccgccgcc ggtgggcatg acgaccagac agtcgcgacc
    23281 ggagagcgca gtatcaataa tcgcttcctg gcccgggcga aactgttggt agccaaaggt
    23341 ttcctgcaaa acctgtttgg cccctgattc cagattcaac acttccgcct gcgccacatt
    23401 aaccccgttc accataaatc aaaacaggcg ctattttcag cgcctgcgag agaaactgca
    23461 atgtttaaaa cacaatccaa tcagaagata tcgttaagca tcacgccgac gccgacacgt
    23521 gtctgattaa aattatagtc gatcagcgat tcgccatagc cgctatacac ctgggtataa
    23581 agccggacat gtttagtgac cggatagctt aatccaactt ccgcgccgcc gtagcctgta
    23641 ttccagttgt actggccttt ggcgcttaat accgcctcgc ccaggtgata accgatttta
    23701 agctggtaat aacccatata tttggtgatg tccggattat cgtcggtact gccaatcacg
    23761 taccatggtt tgacctctac cagccagtta ccgttttcgg ccatcagacg ggtatacaga
    23821 cggttccagc tacgcgaggt ggggtccgaa cgtccgttag agtcatggtt gtagcccatc
    23881 tctacgtcgc gcagcgtcca gccggcaaag cgataatcgg tagcaaaacc aagaaaaagc
    23941 tgcggttcgt agttggtttc gcgaaacggc gaagactctt tactgttgga aagctgccac
    24001 caggatttct gcgtatagga agcgcccagt accgagttcg gccccagtat tccgcgccac
    24061 agcggaaacg ccaggctcaa ctgaaatttc acttcatctt tacgtgcgtt ttcagaccag
    24121 ttgtaggtac ttatggcctc tttgttcaga tcgctggtgt tcgtgtagat caagtagttc
    24181 gtgtcataag ggtaaagcgt aaaagggtta tcatgctcct gtagcatgtt agcgatgata
    24241 cttccccgta ctgcaggcgc atcatgaacc tcttttatcg tagcttcttg tgcatatgcc
    24301 gctaatggca gtagcgtggc tggcaacaac cctctcaaaa tcgcccgcat tcttgacgtt
    24361 ctcctgacga agtattttca gcttgaatca ttctctgcca accattttta catatttaca
    24421 cacatagccg ttagttatcc cttcttaaag tagaaaacaa caattaagaa gcataatatc
    24481 aacatttcat taaccaatgg agtatcagga atctatgtcc gctgtactta ccgctgaaca
    24541 agctctgaaa ttagtgggtg aaatgtttgt ctaccacatg ccgtttaatc gggcgttagg
    24601 gctggagctg gaacgctatg aaaaagcgtt cgcccaactg gccttcaaca accagccgat
    24661 gatggtcggc aactgggcgc aaagcatttt acacggcggc gtgatcgcct ctgcgctgga
    24721 tgtcgccgcc ggactggtat gcgtcggcag cacgctaact cgccacgaaa ccatcagcga
    24781 agatgaacta cgccagcgcc tgtcgcggat gggaacgatt gacctgcgcg tcgattacct
    24841 gcgtccgggc agaggcaacc gctttacggc caccagtagc ctgctgcgcg cagggaataa
    24901 agtggccgtc gcccgcgtgg aattacacaa tgaagatcag ctgtacatcg ccagcgccac
    24961 cgctacttat atggtgggat aaaagcaggt aaactgttgt tacacttcag atacgagttt
    25021 tccggatgga cgcaaaacaa acacggcagg gcgtattact cgctcttgcc gcctatttta
    25081 tttgggggat cgcccccgca tatttcaagc tgatctatta cgttcccgca gatgagatcc
    25141 tgacgcaccg cgtgatttgg tcatttttct ttatggtggc gctgcttagc gtcagccggc
    25201 agtggcgaca ggttaagcgt ttactgaaaa cgccaaagaa gattttcctg ctggccctgt
    25261 ccgccgtact ggtcggcggt aactggctat tgttcatttg ggcggtaaat aatcaccata
    25321 tgctggaggc cagcctgggt tatttcatta atccgctggt taacatcttg ctggggatga
    25381 tttttcttgg cgaacgcttc cgtcgaatgc agtggctggc ggtgattctg gcggtgtgcg
    25441 gcgtgctggt gcaactctgg acctttggct cgctgccgat tatcgcgctg gggctggcgt
    25501 ttagttttgc gttttacggc ctggtgcgta agaagatcgc cgttgaagcg cagacgggta
    25561 tgctggtcga aacgctatgg ctgttgccgg tcgccgcgat ttatctgttt agcatcgccg
    25621 atagcgccac cagccatatg gggcaaaacg cactatcgtt gaacttgctg ttaatggcgg
    25681 cgggtgtggt cactacgatt ccgctgctgt gctttaccgg agcggctacg cgtctgcgtc
    25741 tttctacact gggctttttc cagtatatcg gcccaacgct gatgttttta ctggcggtga
    25801 cgttttatgg cgaagtgccg ggcgcggata agatggtgac atttgcgttt atctgggtcg
    25861 cgctggcgat tttcgtgatg gatgcgattt atacgcagcg taa
//
LOCUS       DAJVBX010000040        25800 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.040, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000040 DAJVBX010000000
VERSION     DAJVBX010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 25800)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25800)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25800
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.040"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            61..2337
                     /gene="phsA"
                     /locus_tag="OPV72_001476"
     CDS             61..2337
                     /gene="phsA"
                     /locus_tag="OPV72_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate reductase PhsA"
                     /protein_id="HCR9913826.1"
                     /translation="MSISRRSFLQGVGIGCSACALGAFPPGALARNPIAGINGKTTLT
                     PSLCEMCSFRCPIQAQVVNNKTVFIQGNPSAPQQGTRICARGGSGVSLVNDPQRIVKP
                     MKRTGPRGDGEWQVISWQQAYQEIAAKMNAIKAQHGPESVAFSSKSGSLSSHLFHLAT
                     AFGSPNTFTHASTCPAGKAIAAKVMMGGDLAMDIANTRYLVSFGHNLYEGIEVADTHE
                     LMTAQEKGAKMVSFDPRLSIFSSKADEWHAIRPGGDLAVLLAMCHVMIDEQLYDASFV
                     ERYTSGFEQLAQAVKETTSEWAAAQADVPADVIVRVTRELAACAPHAIVSPGHRATFS
                     QEEIDMRRMIFTLNVLLGNIEREGGLYQKKNASVYNKLAGEKVAPTLAKLNIKNMPKP
                     TAQRIDLVAPQFKYIAAGGGVVQSIIDAALTQKPYPIKAWIMSRHNPFQTVTCRSDLV
                     KTVEQLDLVVSCDVYLSESAAYADYLLPECTYLERDEEVSDMSGLHPAYALRQQVVEP
                     IGEARPSWQIWKELGEQLGLGQYYPWQDMQTRQLYQLNGDHALAKELRQKGYLEWGVP
                     LLLREPESVRQFTARYPGAIATDSDNTYGEQLRFKSPSGKIELYSATLEELLPGYGVP
                     RVRDFALKKENELYFIQGKVAVHTNGATQYVPLLSELMWDNAVWVHPQTAQEKGIKTG
                     DEIWLENATGKEKGKALVTPGIRPDTLFVYMGFGAKAGAKTAATTHGIHSGNLLPHVT
                     SPVSGTVVHTAGVTLSRA"
     gene            2352..2930
                     /gene="phsB"
                     /locus_tag="OPV72_001477"
     CDS             2352..2930
                     /gene="phsB"
                     /locus_tag="OPV72_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate reductase electron transport protein
                     PhsB"
                     /protein_id="HCR9913827.1"
                     /translation="MNHLTNQYVMLHDEKRCIGCQACTVACKVLNDVPEGFSRVQVQI
                     RAPEQASNALTHFQFVRVSCQHCENAPCVSVCPTGASYRDENGIVQVDKSRCIGCDYC
                     VAACPFHVRYLNPQTGVADKCNFCADTRLAAGQSPACVSVCPTDALKFGRLDESEIQR
                     WVGQKEVYRQQEARSGAVSLYRRKEVHQEGKA"
     gene            2927..3691
                     /locus_tag="OPV72_001478"
     CDS             2927..3691
                     /locus_tag="OPV72_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate reductase cytochrome B subunit"
                     /protein_id="HCR9913828.1"
                     /translation="MNTIWGAELHYAPDYWPLWLIYAGVVVLLMLVGLVIHALLRRML
                     APKTAGGEEHRDYLYSLAIRRWHWGNALLFVLLLLSGLFGHFSLGPVALMVQVHTWCG
                     FALLAFWVGFVLINLTTGNGRHYRVNFSGLVTRCIRQTRFYLFGIMKGEAHPFAATEQ
                     NKFNPLQQLAYLAIMYALVPLLIITGLLCLYPQVAGLGPVMLVLHMALAIIGLLFICA
                     HLYLCTLGDTPGQIFRSMVDGYHRHRTAPRGDKSAV"
     gene            3815..4987
                     /gene="dacD"
                     /locus_tag="OPV72_001479"
                     /pseudo
     CDS             3815..4987
                     /gene="dacD"
                     /locus_tag="OPV72_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461007.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine-type D-Ala-D-Ala carboxypeptidase DacD"
     gene            5138..5605
                     /gene="sbmC"
                     /locus_tag="OPV72_001480"
     CDS             5138..5605
                     /gene="sbmC"
                     /locus_tag="OPV72_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase inhibitor SbmC"
                     /protein_id="HCR9913829.1"
                     /translation="MDYEIRQEQKRKIAGFHMVGPWEHTVKQGFEQLMTWVDRQRIVP
                     VEWIAVYYDNPDVVPAEKLRCDTVVSVAENFILPDNSEGVIVTAIEGGEYATAVARVE
                     DRDFAKPWERFFDVLEQDSAYQIASAPCFETYLNNGMEDGYWDIEMYIPVQRK"
     gene            5724..6782
                     /locus_tag="OPV72_001481"
     CDS             5724..6782
                     /locus_tag="OPV72_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HCR9913830.1"
                     /translation="MRADKSLSPFEIRLYRHYRIVHGIRIALAFILTFLLVRLFSIPE
                     GTWPLITLVVIMGPISFWGNVVPRAFERIGGTILGAALGLVALRLELFSLPLMLVWCA
                     IAMFLCGWLALGKKPYQALLIGITLAVVVGAPAGDMNTALWRGGDVILGALLAMLFTG
                     IWPQRAFLHWRIQLAHCVTAYNRVYQAALSPNLLERPRLDKYLQRLLNDVVKMRGLIT
                     PASKETRIQKSIFEAIQTINRNLVCMLELQINAHWATRASHFVMLNTHTLRETQQMTQ
                     QTLLTIAHALFEGNPQPVLANTGKLNDIAAELRQLMNEQQGDAVAETPIHGYVWLSME
                     TARQLELLSHLICRALRK"
     gene            7027..7362
                     /locus_tag="OPV72_001482"
     CDS             7027..7362
                     /locus_tag="OPV72_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF496 family protein"
                     /protein_id="HCR9913831.1"
                     /translation="METTKPSFQDVLEFVRLFRRKNKLQREIQDIEKKIRDNQKRVLL
                     LDNLSDYIKPGMSVEAIQGIIASMKSDYEDRVDDYIIKNAEISKERRDISKKLKAMGE
                     MKHADVKAE"
     gene            complement(7396..8262)
                     /gene="pduX"
                     /locus_tag="OPV72_001483"
     CDS             complement(7396..8262)
                     /gene="pduX"
                     /locus_tag="OPV72_001483"
                     /EC_number="2.7.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine kinase PduX"
                     /protein_id="HCR9913832.1"
                     /translation="MAVAQCPASCGELIQGWILGSEKLVSCPVDWYSTVAVTAAPPLV
                     NERPLSRAMVERVLAHWQYPAHWSNEIRVDVRSSIPVAKGMASSTADIAATAVATAHH
                     LGHSLDETTLAQLCVSIEPTDSTVFHQLTLFDHNNAATQIACEPPPPIDLLVLESPVT
                     LRTQDYHRLPRQQKLIASSPTLQQAWNLVQEACITQNPLRLGEAATLSAIASQTLLPK
                     PGFTALLSLVEECDLYGLNVAHSGSVVGLMLDRKRHDIARLKGKLAEKKLTRHWPKQH
                     LLKMVTGGVKLQ"
     gene            complement(8356..9570)
                     /gene="pduW"
                     /locus_tag="OPV72_001484"
     CDS             complement(8356..9570)
                     /gene="pduW"
                     /locus_tag="OPV72_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propanediol utilization propionate kinase PduW"
                     /protein_id="HCR9913833.1"
                     /translation="MSYKIMAINAGSSSLKFQLLEMPQGDMLCQGLIERIGMADAQVT
                     IKTHSQKWQETVPVADHRDAVTLLLEKLLGYQIINSLRDIDGVGHRVAHGGEFFKDST
                     LVTDETLAQIERLAELAPLHNPVNALGIHVFRQLLPDAPSVAVFDTAFHQTLDEPAYI
                     YPLPWHYYAELGIRRYGFHGTSHKYVSGVLAEKLGVPLSALRVICCHLGNGSSVCAIK
                     NGRSVNTSMGFTPQSGVMMGTRSGDIDPSILPWIAQRECKTPQQLNQLLNNESGLLGV
                     SGVSSDYRDVEQAANTGNRQAKLALTLFAERIRATIGGYIMQMGGLDALVFTGGIGEN
                     SARARSAVCHNLQFLGLAVDEEKNQRNATFIQTENALVKVAVINTNEELMIAQDVMRI
                     ALPATEGLCVPA"
     gene            complement(9555..10007)
                     /gene="pduV"
                     /locus_tag="OPV72_001485"
     CDS             complement(9555..10007)
                     /gene="pduV"
                     /locus_tag="OPV72_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propanediol utilization protein PduV"
                     /protein_id="HCR9913834.1"
                     /translation="MKRLMFIGPSQCGKTSLTQSLRGEALHYKKTQAIEWSPMAIDTP
                     GEYLENRCLYSALLTSACEADVIALVLNADAQWSPFSPGFTVPMNRPTIGLVTKADLA
                     DPQRISLVAQWLTQAGARQIFITSALNNSGLDAVLDFLNSKEPLCLTK"
     gene            complement(10012..10362)
                     /gene="pduU"
                     /locus_tag="OPV72_001486"
     CDS             complement(10012..10362)
                     /gene="pduU"
                     /locus_tag="OPV72_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propanediol utilization microcompartment protein
                     PduU"
                     /protein_id="HCR9913835.1"
                     /translation="MERQPTTDRMIQEYVPGKQVTLAHLIANPGKDLFKKLGLQDAVS
                     AIGILTITPSEASIIACDIATKSGAVEIGFLDRFTGAVVLTGDVSAVEYALKQVTRTL
                     GEMMQFTTCSITRT"
     gene            complement(10362..10916)
                     /gene="pduT"
                     /locus_tag="OPV72_001487"
     CDS             complement(10362..10916)
                     /gene="pduT"
                     /locus_tag="OPV72_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propanediol utilization microcompartment protein
                     PduT"
                     /protein_id="HCR9913836.1"
                     /translation="MSQAIGILELTSIAKGMELGDAMLKSANVDLLVSKTICPSKFLL
                     MLGGDIGAIQQAIETGTSQAGEMLVDSLVLANIHPSVLPAISGLNSVDKRQAVGIVET
                     WSVAACISAADRAVKGSNVTLVRVHMAFGIGGKCYMVVAGDVSDVNNAVTVASESAGE
                     KGLLVYRSVIPRSHEAMWRQMVEG"
     gene            complement(10919..12247)
                     /gene="pduS"
                     /locus_tag="OPV72_001488"
     CDS             complement(10919..12247)
                     /gene="pduS"
                     /locus_tag="OPV72_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000059462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin reductase PduS"
                     /protein_id="HCR9913837.1"
                     /translation="MSLSADEIRERVRAAGVVGAGGAGFPAHVKLQAQVEIFLVNAAE
                     CEPMLKVDQQLMWQQAARLVRGVQYAMTATGAREGVIALKEKYRRAIDALSPLLPAGI
                     RLHILPDVYPAGDEVLTIWMATGRRVAPAALPASVGVVVNNVQTVLNIARAVEQQFPV
                     TRRTLTVNGAVARPLTVTVPVGMSLHEVLALAGGATVDNPGFINGGPMMGGLITSLDN
                     PVTKTTGGLLVLPKSHPLIQRRMQDERTVLSVARTVCEQCRLCTDLCPRHLIGHELSP
                     HLLVRAVNFHQAATPQLLLSALTCSECNVCESVACPVGISPMRINRMLKRELRAQNQR
                     YEGPLNPADEMAKYRLVPVKRLIAKLGLSPWYQEAPLVEEEPSVEKVTLQLRQHIGAS
                     AVPTVAVGERVTRGQCVADVPPGALGASIHASIDGIVSAISEQAITVVRG"
     gene            complement(12271..13383)
                     /gene="pduQ"
                     /locus_tag="OPV72_001489"
     CDS             complement(12271..13383)
                     /gene="pduQ"
                     /locus_tag="OPV72_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-propanol dehydrogenase PduQ"
                     /protein_id="HCR9913838.1"
                     /translation="MNTFSLQTRLYSGQGSLAVLKRFTNKHIWIICDGFLARSPLLDT
                     LCNALPADNRISVFSEITPDPTIHTVVQGIAQMQALQPQVVIGFGGGSAMDAAKAIVW
                     FSQQSGINIETCVAIPTTSGTGSEVTSACVISDPDKGIKYPLFNNALYPDMAILDPEL
                     VVSVPPQITANTGMDVLTHALEAWVSPHASDFTDALAEKAAKLVFQYLPTAVEKGDCV
                     ATRGKMHNASTLAGMAFSQAGLGLNHAIAHQLGGQFHLPHGLANALLLTTVIRFNAGV
                     PRAAKRYARLAKACGFCPAEANDVTAINALIQQIELLKQRCALPSLAVALKEGRSDFS
                     ARIPAMVQAALADVTLRTNPRPASAEEIRELLEELL"
     gene            complement(13395..14789)
                     /gene="pduP"
                     /locus_tag="OPV72_001490"
     CDS             complement(13395..14789)
                     /gene="pduP"
                     /locus_tag="OPV72_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-acylating propionaldehyde dehydrogenase
                     PduP"
                     /protein_id="HCR9913839.1"
                     /translation="MNTSELETLIRTILSEQLTTPAQTPAQPQGKGIFQSVSEAIDAA
                     HQAFLRYQQCPLKTRSAIISAMRQELTPLLAALAEESANETGMGNKEDKFLKNKAALD
                     NTPGVEDLTTTALTGDGGMVLFEYSPFGVIGSVAPSTNPTETIINNSISMLAAGNSIY
                     FSPHPGAKKVSLKLISLIEEIAFRCCGIRNLVVTVAEPTFEATQQMMAHPRIAVLAIT
                     GGPGIVAMGMKSGKKVIGAGAGNPPCIVDETADLVKAAEDIINGASFDYNLPCIAEKS
                     LIVVESVAERLVQQMQTFGALLLSPADTDKLRAVCLPEGQANKKLVGKSPSAMLEAAG
                     IAVPAKAPRLLIALVNADDPWVTREQLMPMLPVVKVNDFDSALALALKVEEGLHHTAI
                     MHSQNVSRLNLAARTLQTSIFVKNGPSYAGIGVGGEGFTTFTIATPTGEGTTSARTFA
                     RSRRCVLTNGFSIR"
     gene            complement(14786..15796)
                     /gene="pduO"
                     /locus_tag="OPV72_001491"
     CDS             complement(14786..15796)
                     /gene="pduO"
                     /locus_tag="OPV72_001491"
                     /EC_number="2.5.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-domain cob(I)yrinic acid a,c-diamide
                     adenosyltransferase PduO"
                     /protein_id="HCR9913840.1"
                     /translation="MAIYTRTGDAGTTSLFTGQRVSKTHPRVEAYGTLDELNAALSLC
                     ACAAADENHRTLLEAIQQQLFWFSAELASDSEQPSPKQRYISSEEISALEAAIDRAMA
                     RVEPLHSFILPGRCEAASRLHFARTLARRAERRLVELATEVNVRQVLMRYINRLSDCL
                     YALARAEDSDAHQANIIREVSKRYLAASQPTRSKETTPVALSFHDLHQLTRAAVERAQ
                     QLQVPVVVSIVDAHGTETVTWRMPDALLVSSELAPKKAWTAVAMKTATHELSDVVQPG
                     AALYGLESHLQGKVVTFGGGYALWRDGILIGGLGISGGSVEQDMDIAQTAIAAINVGT
                     HQ"
     gene            complement(15806..16080)
                     /gene="pduN"
                     /locus_tag="OPV72_001492"
                     /pseudo
     CDS             complement(15806..16080)
                     /gene="pduN"
                     /locus_tag="OPV72_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228577.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="propanediol utilization microcompartment protein
                     PduN"
     gene            complement(16084..16575)
                     /gene="pduM"
                     /locus_tag="OPV72_001493"
     CDS             complement(16084..16575)
                     /gene="pduM"
                     /locus_tag="OPV72_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propanediol utilization microcompartment protein
                     PduM"
                     /protein_id="HCR9913841.1"
                     /translation="MNGETLQRIVEEIVSRLQRRALSTATLSVAQLRDADCPALFCQH
                     ASLRILLVDLPLLGQLADAETDDAAARKIHDALAFGIRVQLSLHSQLLPVIPVKKLAR
                     LPLVFTDEHGLPLVLHAGSVLGYRDVALLSRGRVVVHRKCIVTAMARDAANARNIQLI
                     KQE"
     gene            complement(16572..17204)
                     /locus_tag="OPV72_001494"
     CDS             complement(16572..17204)
                     /locus_tag="OPV72_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HCR9913842.1"
                     /translation="MDKELLQSTVRKVLDEMRQRPIPLGVSNRHIHLSAQDYERLFPG
                     HPISEKKALLQPGQYATEQTVTLVGPKGQLKNVRLLGPLRSVSQVEISRTDARTLGIA
                     APLRMSGNLKGTPGIRLVSPFGELELPSGVIVAQRHIHMSPLDALILKVSHGDRVSVA
                     IEGDERGLIFNNVAIRVSPDMRLEMHIDTDEANAAGADNPQAFARLVGPR"
     gene            complement(17204..17686)
                     /gene="pduK"
                     /locus_tag="OPV72_001495"
     CDS             complement(17204..17686)
                     /gene="pduK"
                     /locus_tag="OPV72_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460991.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propanediol utilization microcompartment protein
                     PduK"
                     /protein_id="HCR9913843.1"
                     /translation="MANKEHRVKQSLGLLEVCGLALAISCADIMAKSASITLLALEKT
                     NGSGWMVIKIAGDVASVQAAITTGAQFAEQRNGLVAHKVIARPGEGILLAETPSPSVI
                     EPEPEASEIADVVSEAPAEEAPQESELVSCNLCLDPKCPRQKGEPRTLCIHSGKRGEA
                     "
     gene            complement(17690..17965)
                     /gene="pduJ"
                     /locus_tag="OPV72_001496"
     CDS             complement(17690..17965)
                     /gene="pduJ"
                     /locus_tag="OPV72_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propanediol utilization microcompartment protein
                     PduJ"
                     /protein_id="HCR9913844.1"
                     /translation="MNNALGLVETKGLVGAIEAADAMVKSANVQLVGYEKIGSGLVTV
                     MVRGDVGAVKAAVDAGSAAASVVGEVKSCHVIPRPHSDVEAILPKSA"
     gene            complement(17985..18335)
                     /gene="pduH"
                     /locus_tag="OPV72_001497"
     CDS             complement(17985..18335)
                     /gene="pduH"
                     /locus_tag="OPV72_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propanediol dehydratase reactivase beta subunit
                     PduH"
                     /protein_id="HCR9913845.1"
                     /translation="MDSNHSAPAIVITVINDCASLWHEVLLGIEEEGIPFLLQHHPAG
                     DVVDSAWQAARSSPLLVGIACDRHSLVVHYKNLPASAPLFTLMHHQDSQAQRNTGNNA
                     ARLVKGIPFRDLNS"
     gene            complement(18325..20157)
                     /gene="pduG"
                     /locus_tag="OPV72_001498"
     CDS             complement(18325..20157)
                     /gene="pduG"
                     /locus_tag="OPV72_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propanediol dehydratase reactivase alpha subunit
                     PduG"
                     /protein_id="HCR9913846.1"
                     /translation="MRYIAGIDIGNSSTEVALARQDETGALTITHSALAENTGIKGTL
                     RNVFGIQEALALVAKRAGINVSDISLIRINEATPVIGDVAMETITETIITESTMIGHN
                     PKTPGGAGLGVGITITPEELLTRPADSSYILVVSSAFDFADIANVINASMRAGYQITG
                     VILQRDDGVLVSNRLEKSLPIVDEVLYIDCIPLGMLAAIEVAVPGKVIETLSNPYGIA
                     TVFNLNADETKNIVPMARALIGNRSAVVVKTPSGDVKARAIPAGNLELQAQGRTVRVD
                     VAAGAEAIMKAVDGYGKLDNVNGEAGTNIGGMLEHVRQTMAELTNKPSSEIFIQDLLA
                     VDTSVPVSVTGGLAGEFSLEQAVGIASMVKSDRLQMAMIAREIEQKLNIDVQIGGAEA
                     EAAILGALTTPGTTRPLAILDLGAGSTDASIINPKGEIIATHLAGAGDMVTMIIAREL
                     GLEDRYLAEEIKKYPLAKVESLFHLRHEDGSVQFFPTPLPPAVFARVCVVKPDELVPL
                     PGDLALEKVRAIRRSAKERVFVTNALRALRQVSPTGNIRDIPFVVLVGGSSLDFEVPQ
                     LVTDALAHYRLVAGRGNIRGSEGPRNAVATGLILSWHKEFAYGQ"
     gene            complement(20364..20885)
                     /gene="pduE"
                     /locus_tag="OPV72_001499"
     CDS             complement(20364..20885)
                     /gene="pduE"
                     /locus_tag="OPV72_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propanediol dehydratase small subunit PduE"
                     /protein_id="HCR9913847.1"
                     /translation="MNTDAIESMVRDVLSRMNSLQGDAPAAAPAAGGTSRSAKVSDYP
                     LANKHPEWVKTATNKTLDDFTLENVLSNKVTAQDMRITPKTLRLQASIAKDAGRDRLA
                     MNFERAAELTAVPDDRILEIYNALRPYRSTKEELLAIADDLENRYQAKICAAFVREAA
                     GLYVERKKLKGDD"
     gene            complement(20900..21574)
                     /gene="pduD"
                     /locus_tag="OPV72_001500"
     CDS             complement(20900..21574)
                     /gene="pduD"
                     /locus_tag="OPV72_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propanediol dehydratase medium subunit PduD"
                     /protein_id="HCR9913848.1"
                     /translation="MEINEKLLRQIIEDVLRDMKGSDKPVSFNTPAASTAPQTAAPAG
                     DGFLTEVGEARQGTQQDEVIIAVGPAFGLAQTVNIVGLPHKSILREVIAGIEEEGIRA
                     RVIRCFKSSDVAFVAVEGNRLSGSGISIGIQSKDTTVIHQQGLPPLSNLELFPQAPLL
                     TLETYRQIGKNAARYAKRESPQPVPTLNDQMARPKYQAKSAILHIKETKYVVTGKNPQ
                     ELRVTL"
     gene            complement(21585..23249)
                     /gene="pduC"
                     /locus_tag="OPV72_001501"
     CDS             complement(21585..23249)
                     /gene="pduC"
                     /locus_tag="OPV72_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propanediol dehydratase large subunit PduC"
                     /protein_id="HCR9913849.1"
                     /translation="MRSKRFEALAKRPVNQDGFVKEWIEEGFIAMESPNDPKPSIKIV
                     NGAVTELDGKPVSEFDLIDHFIARYGINLNRAEEVMAMDSVKLANMLCDPNVKRSEIV
                     PLTTAMTPAKIVEVVSHMNVVEMMMAMQKMRARRTPSQQAHVTNVKDNPVQIAADAAE
                     GAWRGFDEQETTVAVARYAPFNAIALLVGSQVGRPGVLTQCSLEEATELKLGMLGHTC
                     YAETISVYGTEPVFTDGDDTPWSKGFLASSYASRGLKMRFTSGSGSEVQMGYAEGKSM
                     LYLEARCIYITKAAGVQGLQNGSVSCIGVPSAVPSGIRAVLAENLICSSLDLECSSSN
                     DQTFTHSDMRRTARLLMQFLPGTDFISSGYSAVPNYDNMFAGSNEDAEDFDDYNVIQR
                     DLKVDGGLRPVREEDVIAIRNKAARALQAVFAGMGLPPITDEEVEAATYAHGSKDMPE
                     RNIVEDIKFAQEIINKNRNGLEVVKALAQGGFTDVAQDMLNIQKAKLTGDYLHTSAII
                     VGDGQVLSAVNDVNDYAGPATGYRLQGERWEEIKNIPGALDPNEID"
     gene            complement(23268..24080)
                     /gene="pduB"
                     /locus_tag="OPV72_001502"
     CDS             complement(23268..24080)
                     /gene="pduB"
                     /locus_tag="OPV72_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propanediol utilization microcompartment protein
                     PduB"
                     /protein_id="HCR9913850.1"
                     /translation="MSSNELVEQIMAQVIARVATPEQQAIPGQPQPIRETAMAEKSCS
                     LTEFVGTAIGDTLGLVIANVDTALLDAMKLEKRYRSIGILGARTGAGPHIMAADEAVK
                     ATNTEVVSIELPRDTKGGAGHGSLIILGGNDVSDVKRGIEVALKELDRTFGDVYGNEA
                     GHIELQYTARASYALEKAFGAPIGRACGVIVGAPASVGVLMADTALKSANVEVVAYSS
                     PAHGTSFSNEAILVISGDSGAVRQAVTSAREIGKTVLATLGSEPKNDRPSYI"
     gene            complement(24077..24361)
                     /gene="pduA"
                     /locus_tag="OPV72_001503"
     CDS             complement(24077..24361)
                     /gene="pduA"
                     /locus_tag="OPV72_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propanediol utilization microcompartment protein
                     PduA"
                     /protein_id="HCR9913851.1"
                     /translation="MQQEALGMVETKGLTAAIEAADAMVKSANVMLVGYEKIGSGLVT
                     VIVRGDVGAVKAATDAGAAAARNVGEVKAVHVIPRPHTDVEKILPKGISQ"
     gene            24886..25680
                     /gene="pduF"
                     /locus_tag="OPV72_001504"
     CDS             24886..25680
                     /gene="pduF"
                     /locus_tag="OPV72_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propanediol diffusion facilitator PduF"
                     /protein_id="HCR9913852.1"
                     /translation="MNDSLKAQCGAEFLGTGLFLFFGIGCLSALKVAGASLGLWEICI
                     IWGLGISLAVYLTAGISGGHLNPAVTIALWLFACFPKQKVLPYIIAQFAGAFGGDLLA
                     YVLYSSLFTEFETAHHMVRGSVESLQLASIFSTYPAAALNVWQAALVEVVITSILMGM
                     IMALTDDGNGIPKGPLAPLLIGILVAVIGASTGPLTGFAMNPARDFGPKLFTWLAGWG
                     NMAMSGGREIPYFIVPIVAPVIGACAGAAIYRYFIGKNLPCNRCKL"
BASE COUNT         5454 a         6989 c         7351 g         6006 t
ORIGIN      
        1 cgacatttca taatacaaat taaatataat cttcagctat atctaataac aggaggttat
       61 atgagcatta gtcgtcgttc ttttttgcag ggggtaggca taggctgctc tgcctgcgcg
      121 ctgggcgctt ttccgcccgg ggcgctggcg cgcaacccga ttgccggcat taacggtaaa
      181 accacgctaa cgccaagttt gtgcgaaatg tgttcctttc gttgccctat tcaggcgcag
      241 gtagtcaata acaagaccgt ttttatccag ggcaatcctt ctgcgccgca gcaggggacg
      301 cgcatatgcg ccaggggcgg gagcggcgtc agcctggtca atgacccgca acggattgta
      361 aaacctatga aacgcaccgg gccacgcggt gacggtgaat ggcaggtgat tagctggcaa
      421 caggcttacc aggaaatcgc ggcgaaaatg aatgccatca aagcgcagca tggccccgag
      481 agcgtggctt tctcttccaa atcgggctcg ctctccagcc atcttttcca tctggctacg
      541 gcctttggtt cgcctaatac ctttactcac gcctcaacat gccctgccgg gaaagccatt
      601 gcggcaaaag tgatgatggg cggcgatctg gcgatggata tcgctaacac gcgctatctg
      661 gtttcgtttg gccacaattt gtatgaaggg attgaagttg ccgataccca tgagttaatg
      721 accgcgcagg agaagggggc caaaatggtg agcttcgatc cgcgtttgtc gatattttcc
      781 agcaaggcgg atgagtggca cgctattcgt cccggagggg atttagcggt tctgctggcg
      841 atgtgccacg tcatgattga tgaacaactc tacgatgcgt cttttgttga gcgttatacc
      901 agcggatttg aacagttagc acaggcggta aaagagacga cgtcggaatg ggccgccgcg
      961 caggccgatg tcccagccga cgtcattgtc cgggtgacac gcgaactggc cgcctgtgcg
     1021 cctcacgcta ttgtcagtcc tggtcatcgc gcgacgttct cgcaggaaga gatcgatatg
     1081 cggcgtatga tttttacgct taatgtgctg ctcggtaata ttgagcgcga aggcgggcta
     1141 tatcagaaaa aaaacgcgtc ggtttacaac aaactggccg gagaaaaggt cgcgccaacg
     1201 ctggcgaaac tcaacattaa aaatatgccg aaaccgacgg cgcaacgaat cgatctggtc
     1261 gcacctcagt ttaaatatat cgccgctggc ggcggcgtgg tgcaaagcat tattgacgcg
     1321 gcgttaaccc agaagcctta cccgataaag gcgtggatta tgtcgcggca taatcctttc
     1381 cagaccgtca cctgtcgttc ggacctggta aaaaccgttg agcaactgga tctggtggtc
     1441 agctgcgatg tctatttgag cgagagcgcg gcatatgccg actatctgct gccggaatgc
     1501 acctatctcg aacgggacga agaggtatcc gatatgtcgg gtctgcaccc ggcttacgct
     1561 ctgcgccaac aggtcgtaga gccgattggc gaggcgcgtc cgagttggca aatctggaaa
     1621 gaacttggcg agcagttggg attagggcag tactatccgt ggcaggatat gcagacgcgc
     1681 caactctatc agttgaacgg cgaccatgcc ttagcgaagg aactgcgaca gaaagggtat
     1741 ctcgaatggg gcgttccgct gctattacgc gaaccagaat ccgttcgtca gtttacggcg
     1801 cgttaccccg gcgctatcgc gacggacagt gacaacacct atggcgaaca gcttcgcttc
     1861 aaatcgccct ccggcaaaat cgaactttat tccgcaaccc tggaggaatt gctccctggc
     1921 tacggcgttc cgcgcgttcg tgactttgcg ctgaaaaaag agaatgagct ttacttcatt
     1981 caaggcaagg tggccgtgca taccaatggc gcgacgcagt acgtaccttt actcagcgag
     2041 ctaatgtggg ataacgcggt ctgggtccat ccgcaaacag cgcaagaaaa aggcattaag
     2101 accggcgatg agatctggct ggaaaatgcc acgggtaaag agaaaggtaa ggcgctggtg
     2161 acgcccggta ttcgcccgga tacgcttttt gtctatatgg gatttggcgc taaagctggg
     2221 gctaaaacgg cggcgacgac acacggtatc cactctggca atttactgcc gcacgtgacg
     2281 agtccggtat ccggtacggt agtgcatacc gcaggcgtga cgctgagccg ggcatgaggg
     2341 aggagggaac catgaatcat ttaacgaatc agtacgtcat gctgcatgat gaaaaacgtt
     2401 gtatcggctg ccaggcgtgt accgttgcct gcaaagtgct taatgacgta ccggagggat
     2461 ttagccgcgt acaggtacaa attcgcgccc ctgaacaggc atccaacgca ctaacccatt
     2521 ttcaatttgt ccgcgtctcc tgtcagcact gtgaaaatgc gccatgtgtc agcgtttgtc
     2581 ctaccggagc gtcatatcgt gatgaaaacg ggatcgtgca ggtggataaa tcgcgctgta
     2641 ttggctgcga ttattgtgtt gccgcgtgtc ctttccatgt gcgctatctg aatccgcaaa
     2701 ccggcgtcgc cgacaagtgt aacttctgtg ccgacacgcg gttggcggct ggccagtctc
     2761 cggcgtgcgt atccgtttgc ccaacggacg cgctgaaatt cggcagactg gatgagagcg
     2821 agatccagcg ctgggtcggt cagaaagagg tctatcgcca gcaggaagcg cgtagcggcg
     2881 cggtcagtct gtaccgtcgt aaagaagtcc atcaggaggg taaagcatga atactatctg
     2941 gggagcggaa ctacattatg cgccagatta ttggccgctg tggttaattt acgcaggcgt
     3001 cgtggtgctg ctcatgcttg ttgggctggt tatccatgcg ttattgcgcc ggatgctggc
     3061 gccaaaaacg gcgggcggcg aagagcatcg tgactatctc tactcgctgg cgattcgccg
     3121 ttggcattgg ggaaatgcat tactgtttgt tttattactg ttaagcggtt tatttggtca
     3181 tttttctctc ggccctgtag cgctaatggt acaagtgcat acctggtgtg gttttgcctt
     3241 actggctttc tgggtcgggt ttgtgctgat caacctcacc acaggtaacg ggcgtcacta
     3301 tcgggtaaat ttttccggac tagtgacgcg ctgcatacgc cagacccgtt tttacctttt
     3361 tggcatcatg aaaggggaag cgcatccgtt cgcggcaaca gagcagaata agttcaatcc
     3421 actgcagcaa ctggcatatc tggcgattat gtacgcgctg gtaccgctgt taatcatcac
     3481 cggtttgctg tgtctctatc cgcaggttgc gggtctgggc cctgtgatgc tggtgctgca
     3541 tatggcgctt gctatcatcg gcttactgtt tatttgcgcg catctctatc tgtgtactct
     3601 tggcgacacg ccgggacaaa ttttccgtag catggttgac ggctatcatc gtcatcgtac
     3661 cgcgccgcgc ggggataagt ccgccgtctg agcgtatcca taaaataaag tcagcaagaa
     3721 aatgtgcctt gtgtcacatt ttcttgcaat ttatccatgt ttgtttaact gaacttccgt
     3781 aaaaagaacg gcaaattgag accatcctga agacatgctg ttgaaacgcc gtttgtttat
     3841 tgccgcttct ttattcgcga tgcacctttc tcctgcgctt gcggccgatg ccgtaagttt
     3901 tgctccccaa ccgccagcca ttgatgcagg cgcctgggtg ttgatggatt acactacggg
     3961 acaggttctt accgccggta atgaacacca gcaacgtaat cccgccagcc ttaccaagct
     4021 aatgacgggc tacgtcgtcg atcgcgccat cgatagtcat cgtatcagcc ctgacgatat
     4081 cgtcaccgtt gggcgcgacg cctgggcgaa ggataatccg gtgtttgtcg gctcctcgtt
     4141 gatgttttta aaagaagggg atcgcgtgtc ggtacgcgat ttaagccgtg gcttaattgt
     4201 ggattccggt aacgatgcct gtgtggcgct ggcggattat atcgcgggcg ggcagccgca
     4261 gtttgtggcg atgatgaaca gctatgtgaa aaaactcaat ttgcaggata cccattttga
     4321 aaccgtccac ggtctggatg cgccgggaca acatagctcc gcgtatgatc tggccgtact
     4381 ctcccgggcg attattcacg gcgaacctga attttatcac atgtacagcg agaaaagcct
     4441 gacctggaac ggcatcacac agcagaaccg caacggcttg ttatgggata agaccatgca
     4501 tatcgatggg cttaaaaccg gacacacatc gggggcggga tttaatctta tcgcatcggc
     4561 ggtggacggg cagcgtcgac ttatcgccgt cgtgatggga gcgaaaagtt cgaaaggacg
     4621 cgaggaacag gcgcgaaaac tgttgcagtg gggccagcaa aactttgcga cggtgcagat
     4681 tttgcacagc ggcaaaaaag tgggcagcga gcggatctgg tacggagaca aagaaaagat
     4741 tgcgctgggt acggaacagg atttctgaat ggcgctgccc aaagcggaaa ttccgcatat
     4801 caaagcaaaa tatgtgctgg atagaaaaga gctggaggcg ccaatcgccg cccatcaacg
     4861 ggtaggtgaa atagagctct acgatcggga taaactgatc gctcagtggc cgctggtcac
     4921 tctggaatcg gtgggtaaag gcggtatgtt ctctcgtctg agcgactatt ttcagcataa
     4981 agcgtaagcc gttgtcacac accgttcacc gtcatctgag gtgtcaaaag ggcgggattg
     5041 cgaggttgct cacaaaatga tcacgctgtc cttgtgaccg taaaaggctg taattatact
     5101 gtacattaat acagtatagt aaagtgacgg aggcagcatg gattacgaaa tcaggcagga
     5161 acaaaaacgc aagatagccg gtttccacat ggtcggtcca tgggaacaca ccgtgaagca
     5221 gggttttgaa caactgatga cgtgggtgga tcgacagcgg atcgtgccag ttgaatggat
     5281 tgccgtctat tacgacaatc cagatgtcgt acctgcagaa aaactccgct gcgataccgt
     5341 ggtgtccgtg gcagagaatt tcatcctgcc ggacaatagc gaaggcgtaa tcgtgaccgc
     5401 cattgaaggc ggcgaatatg ccactgctgt cgcgcgagtg gaagaccgtg actttgcgaa
     5461 gccgtgggaa cggttttttg atgtcctcga gcaggatagc gcttatcaga tagcctctgc
     5521 gccctgtttt gaaacctatc tgaataacgg catggaagat ggatactggg atattgaaat
     5581 gtatattccg gtacagcgga agtgatcgac tggtttcctg gctgaaaaga gcggacggat
     5641 aatgtgttcc gtccgccagt gcgctatttt tgctataaag caggtacaat gcattttttg
     5701 ccattcccgt aaggagcgca agcgtgcgtg ccgataagtc attaagccct tttgaaatac
     5761 ggttgtaccg tcattatcgc atcgtgcatg gcatacgtat cgccctggcg ttcattctta
     5821 cctttctgct ggttcgtctg ttttctattc ccgagggcac atggccgcta atcacgttag
     5881 tggtgattat ggggcccatc tcattctggg gaaatgtagt gcctcgtgct tttgagcgca
     5941 taggcggtac gattctgggc gcggcgttag ggctggtggc gctacgcctg gagctctttt
     6001 ccttaccgct gatgctggtg tggtgtgcga tagcgatgtt tttgtgcggc tggctggcct
     6061 tagggaaaaa accgtatcag gcgctactga taggcataac gctcgccgtt gttgtcggcg
     6121 ctcccgctgg tgatatgaat acggcattat ggcgtggcgg ggatgtgatt ttgggggcgc
     6181 tactggcaat gttgtttacc ggcatctggc cccagcgcgc ctttttgcac tggcgcatcc
     6241 aactggcgca ttgcgtcacg gcgtataatc gggtgtatca ggcagcgctg tcgccgaatt
     6301 tgctggagcg cccccggttg gataaatatt tgcaacggtt gctgaacgat gtcgtcaaaa
     6361 tgcgcgggct gataacgcca gccagtaaag aaacccggat acaaaaatct attttcgagg
     6421 ccattcagac catcaaccgc aatctggttt gtatgcttga attacaaatc aatgcccact
     6481 gggcgacgcg cgccagccat tttgtgatgc ttaacacgca cacattgcgt gaaacccagc
     6541 agatgacgca gcaaaccttg ctaacgatcg cccacgcgtt gtttgaaggc aacccgcagc
     6601 cggtactagc aaataccggt aaactgaatg atattgctgc cgagttgcga cagctaatga
     6661 acgagcagca gggcgacgcg gtggctgaaa cccccatcca cggctatgtt tggctaagta
     6721 tggaaacggc ccgacagttg gaactgcttt cacacttgat ctgccgggct ttgcgcaaat
     6781 aaaaagcaga tggggtgaat gaatttgttg ctgcttcgat tcagcaaaga ttaagagtat
     6841 gatactaata taaggataaa atgagtgcta ctggcaacga ttttatcccc gaaccttcag
     6901 gtttccccag acggcgacgt aacggtgttt cttctggcgg cttgaagtat gacggggata
     6961 aacgtaatgt ttatccacta gcagttgctt aacgaatccg aatctcacat tatcaggggt
     7021 gtaaaaatgg aaacaaccaa gccttctttc caggacgtgc tggagtttgt tcgtctgttc
     7081 cgtcgcaaaa ataaactgca gcgtgaaatt caggacattg agaagaagat ccgtgacaac
     7141 cagaagcgtg tgctgctgct ggacaacctg agcgactaca tcaagccagg tatgagcgtt
     7201 gaggcgattc agggtatcat cgccagtatg aaaagcgact atgaagatcg cgttgatgac
     7261 tacatcatta aaaatgccga aatctccaaa gagcgtcgcg acatttccaa aaagctgaaa
     7321 gcgatgggcg aaatgaaaca cgccgatgta aaagccgaat aatgcgctac ggcagtggga
     7381 gcgtatatca ggctctcact gcagtttgac cccgcctgtg accatcttga gtaaatgttg
     7441 ttttggccag tgtcgggtaa gttttttctc tgccagctta cctttcagac gcgcaatatc
     7501 atgacgtttc cggtccagca tcagacccac cacgctaccg ctatgcgcca cgttcaatcc
     7561 gtataaatca cactcttcga ccagcgacag cagggcggta aagcccggct taggtaacag
     7621 cgtctggctg gcgatagcgc taagcgtagc cgcctcaccc agtcggagcg gattttgcgt
     7681 tatacaggct tcctgcacca gattccaggc ctgctgcaag gttggtgaac ttgctattaa
     7741 tttctgctgg cgagggagac ggtggtaatc ttgcgtgcgc agtgtgaccg ggctttccag
     7801 taccagcaaa tcgattggcg gcggtggctc gcaggcgatt tgcgtggccg cattattatg
     7861 atcaaacagc gttaactgat gaaaaacggt gctatcagtg ggttcgattg agacgcaaag
     7921 ctgtgcaagg gtggtttcat ccagcgaatg gccaagatga tgcgccgttg ccaccgccgt
     7981 agcggcaata tctgcggtgc tgctggccat gcctttggca acgggaattg acgaacgcac
     8041 atcgacgcga atctcgttac tccagtgcgc aggatactgc cagtgcgcca gaacgcgctc
     8101 caccatcgcc cgcgacaatg gacgctcgtt taccaacggc ggcgcagccg tgactgctac
     8161 ggtgctgtac cagtcaacgg ggcaggagac cagtttctca ctgcccagaa tccatccctg
     8221 gataagttcc ccgcatgagg cggggcattg cgcaacagcc acgttatcac ctttcaggta
     8281 cgaatagtgt gcgcgcatag tgtcatggta aaagcgttat taccatgact tgccgcaatg
     8341 cgtcgtatac ccctctcagg ctggtacaca aagcccttcc gtggccggta gcgcaatgcg
     8401 cataacgtct tgtgcgatca ttaactcttc gttggtgttg atgacggcga ctttcaccag
     8461 ggcgttctcc gtctggataa atgttgcatt acgttgattt ttctcttcat caacggctaa
     8521 gcctaaaaat tgcaaattat ggcaaaccgc cgatctggcg cgcgctgagt tctcgccaat
     8581 tcccccagtg aataccagag catccagtcc tcccatttgc ataatatagc caccaatggt
     8641 ggcgcgaatg cgttcggcaa acagcgtgag agcgagttta gcctgccggt taccggtatt
     8701 ggctgcctgt tcgacatcgc ggtaatcaga cgacacgcca gaaacgccca gcaagcctga
     8761 ctcattattt aataactgat tcaactgttg cggcgttttg cattcgcgct gggctatcca
     8821 cggcagaata gagggatcaa tatctccgct acgggtgccc atcatcacgc ctgactgcgg
     8881 cgtaaagccc atcgacgtat tgaccgaacg tccgttcttg atggcgcaga cgctgctacc
     8941 gtttccaaga tgacaacaaa tcacccgtaa tgcgctgagt ggtacgccca gcttttcagc
     9001 cagaacgccg ctgacatact tatggctggt gccatgaaag ccataacggc gaatccccag
     9061 ttcagcgtaa taatgccagg gaagcgggta aatataggcg ggttcatcca gcgtctggtg
     9121 aaatgccgta tcaaacacgg ctacagaagg ggcatcaggc aacagttgac gaaaaacgtg
     9181 aatacccaac gcgtttaccg ggttgtgaag cggggccagt tcagcaagac gttcgatttg
     9241 cgctaacgtt tcatccgtga ccagcgtcga gtctttaaaa aactcaccgc cgtgcgccac
     9301 acgatggccc accccgtcaa tgtcccgcag actgttaatg atttgataac ccagcagctt
     9361 ttccagaagc agcgttaccg catcgcgatg atcggcaacg gggacggttt cctgccattt
     9421 ttggctgtgc gtcttaattg tcacctgcgc atccgccata ccgatacgct caatcagccc
     9481 ctggcagagc atgtcgccct gcggcatctc cagcagctgg aactttaacg atgagctgcc
     9541 ggcgttaatg gccattattt tgtaagacat aaaggttcct tcgaattcag aaaatccagc
     9601 acggcgtcga gacccgaatt attcaacgcg ctggtaataa aaatctgccg ggcgccagcc
     9661 tgcgtaagcc attgtgcgac cagcgaaata cgctgcgggt cggcgagatc ggctttggtg
     9721 acaaggccaa tcgtcgggcg gttcatcggg acggtaaaac ccggagaaaa cggcgaccac
     9781 tgagcgtcgg catttaacac cagggcgata acgtcggcct cgcaggcgct ggtcagcagg
     9841 gcgctgtaca ggcagcggtt ctccaggtat tcgcccggcg tgtcgatagc catcggcgac
     9901 cattcaatgg cctgggtttt cttgtaatgg agcgcttcgc cacgcaggct ttgggtcagc
     9961 gaagttttcc cgcactggct ggggccgata aacatcagac gcttcattgg attacgtccg
    10021 ggtgatcgag caggtagtga actgcatcat ctcgcccagg gtgcgcgtta cctgcttgag
    10081 ggcatattcc acggcggaaa catcgccggt cagcaccaca gcaccggtaa agcggtcaag
    10141 aaaaccaatc tccaccgcgc cggattttgt agcaatatcg caggcgataa tcgacgcttc
    10201 gctgggcgtg atggtgagga tgccaatggc ggaaaccgca tcctgcaggc ccagcttctt
    10261 aaataaatct ttccccggat tagcaatcag gtgcgcgagg gtcacctgtt tccccggcac
    10321 gtattcctga atcatgcgat ccgttgtcgg ttgtctttcc attatccctc caccatctgt
    10381 cgccacatgg cttcatgcga gcgtgggatc accgaacggt aaaccagcag ccctttttcg
    10441 cccgcgcttt cgctggcgac cgtcacggcg ttattgacgt cagaaacgtc gcccgccacc
    10501 accatgtagc atttaccgcc gatgccgaag gccatatgca cccgcaccag ggtgacgttt
    10561 gagcctttca ccgcccggtc tgcggcgcta atgcaggccg ccacgctcca ggtttcgacg
    10621 atgccgaccg cctgacgctt atcgacgctg ttcaggccgc tgatggccgg aagtacgctg
    10681 ggatgaatat ttgccagcac caggctgtcg acgagcatct cgccggcctg cgacgtaccg
    10741 gtttcaatgg cctgctggat agcgccgata tcgccgccca gcatcagtaa aaacttactt
    10801 gggcagatgg tcttgctgac cagtagatcg acgttggcgc ttttcagcat ggcatcacca
    10861 agctccatgc ctttggcgat gctggtgagt tctaaaattc ctatagcctg agacatggtt
    10921 aacctcttac aacagtgatg gcctgttcgc tgatggccga aacaatgccg tcgatgctgg
    10981 cgtgaatgga tgcgccgagc gcgccaggcg ggacatcggc aacgcattgc ccgcgagtca
    11041 cgcgctcgcc gacggcaaca gtcggtactg cgctggcacc aatatgctgg cgcagctgca
    11101 aagtgacttt ttctactgac ggctcttctt caaccagcgg cgcttcctgg taccaggggc
    11161 ttagtcccag tttggcgatc agccgcttca ccggcaccag gcgatatttc gccatttcgt
    11221 cggccggatt cagcggccct tcgtagcgct ggttttgcgc ccgcagctcg cgttttaaca
    11281 tgcggttgat gcgcatcggc gagatcccga ccgggcaggc cacgctttcg caaacgttgc
    11341 attccgagca ggtaagggcg ctcagcagca gttgcggcgt ggcagcctga tgaaagttca
    11401 ccgcccgcac cagcaggtgc ggagagagtt cgtggccgat cagatgtcgt gggcagagat
    11461 cggtacagag tcggcactgt tcgcagacgg tgcgcgcgac ggaaagcact gtgcgctcgt
    11521 cctgcatcct gcgctggata agcggatggc tttttgggag caccagcagg ccgccggtag
    11581 ttttcgtcac cgggttatca agagaggtaa tcaggccacc catcatcggg ccgccgttaa
    11641 taaaaccggg gttgtcgacc gtcgcgccgc cagccagcgc cagcacttca tgcagtgaca
    11701 tgccgacagg aacggtaacg gtcaacggtc tggcgaccgc gccgttcacg gtcaacgtgc
    11761 gacgagtgac cggaaactgc tgctcgaccg cccgggcaat attcagcacc gtttgcacgt
    11821 tattgacgac tacgccgacg ctggcaggca gcgcggcagg ggcgacccga cgaccggttg
    11881 ccatccagat agtcagcacc tcatcgcccg cgggatatac atccggcagg atatgcaggc
    11941 ggataccggc tggcagtagt ggggagaggg cgtcgatggc ccggcggtat ttttctttca
    12001 gggcaatcac cccttcgcgc gcgccggttg ccgtcatggc gtactgcacg ccgcggacaa
    12061 gacgcgcggc ctgctgccac atcagttgct ggtcaacttt gagcatcggt tcacactcgg
    12121 cggcgttcac cagaaaaatc tctacctgcg cctgtagctt aacgtgggcg ggaaaacctg
    12181 cgccgcccgc accgacaacg cccgctgcgc gaacgcgctc acgaatttca tcggcgctaa
    12241 gggacattta aacgctgttg atggcggcgc tcatagcagt tcctccagca gttcacgaat
    12301 ttcctcggcg ctggccgggc gcgggttggt gcgcaacgtg acatccgcca gcgcggcctg
    12361 caccatcgct ggaatacgtg cggaaaagtc ggatcttcct tcttttagcg caacggccag
    12421 tgagggaagg gcacagcgtt gcttaagcag ttcgatttgc tgaatcagcg cattgatcgc
    12481 cgtgacatcg ttggcttctg ccgggcaaaa accgcaggct ttggccagcc gcgcgtagcg
    12541 tttggctgcg cgcggaactc cggcgttaaa acggatcacc gtcgtgagca gcagcgcatt
    12601 ggccaggcca tgcggaagat gaaactgtcc gccaagctgg tgggctatcg cgtggttaag
    12661 ccccagcccc gcctggctga aggccatccc ggcgagcgtt gaggcgttat gcatttttcc
    12721 tcgcgtcgcc acgcagtcgc ctttttccac cgccgtcggc agatactgga acaccagttt
    12781 ggcggctttt tccgccagcg cgtcggtaaa gtcgctggcg tgcggtgaca cccaggcctc
    12841 cagggcgtgg gtcagcacgt ccatgccggt gttggcggta atctgcggcg gtacgctgac
    12901 caccagctcc gggtcgagga tcgccatatc cggatacagc gcattgttga acagcggata
    12961 cttgatgcct ttatccggat cgctaattac gcaggcgctg gtgacttccg aaccagtgcc
    13021 gctggtggtc gggatcgcca cgcaggtttc gatattgatg ccgctttgtt ggctaaacca
    13081 gacaatcgct ttcgccgcgt ccattgccga gccgccgcca aaaccaatca ccacctgcgg
    13141 ctgcagggcc tgcatttgcg caatgccctg caccacggta tggatggtgg ggtccggcgt
    13201 tatctcgcta aagacgctga tgcggttatc tgcgggcagc gcgttacaca gggtatccag
    13261 cagcggcgag cgtgccagaa agccatcgca gattatccag atgtgcttat tggtaaagcg
    13321 cttgagcacc gccaggctgc cctgaccgct gtacaaccgc gtttgtagtg agaaggtgtt
    13381 catcgcgacc tcggttagcg aatagaaaag ccgttggtca gcacgcagcg ccgggagcgg
    13441 gcaaaagtac gcgctgacgt tgttccttca ccggttggcg tggcaatggt aaaggtggta
    13501 aagccttcgc cgccgacgcc gatcccggca taagaagggc cgtttttgac gaatatcgag
    13561 gtttgcaggg tgcgggccgc gaggttcagg cgcgacacgt tctgcgagtg catgatcgcg
    13621 gtgtgatgca acccctcttc aaccttcagg gccagtgcca gcgcgctatc gaaatcgtta
    13681 acttttacca ccggcagcat cggcatcagc tgttctctgg tgacccacgg atcgtcagcg
    13741 ttaaccagcg caatcagcag acgcggcgct tttgcaggga cagcgatccc ggcggcttcc
    13801 agcatggccg atgggctctt gccgaccagt tttttattcg cctggccttc aggcaggcag
    13861 acggcgcgga gtttgtcggt atcggcaggg cttagcagca gcgcgccgaa ggtttgcatt
    13921 tgctgcacca gacgttcggc gacgctctcc accacgatca ggctcttctc ggcaatgcag
    13981 ggcaggttgt aatcgaatga cgcgccgttg atgatatctt ccgccgcttt caccaggtcc
    14041 gctgtttcat caacgatgca gggcggattg ccagcgccag cgccaatcac cttcttaccg
    14101 ctcttcatgc ccatggccac aatgccgggg ccgccggtaa tagccagtac cgcgattcgc
    14161 gggtgggcca tcatctgctg ggtcgcttcg aaagtcggtt ccgccacggt caccaccaga
    14221 ttgcggatgc cgcagcagcg gaaggcaatc tcttcaatca gactaatcag cttcagagag
    14281 acctttttcg ctcccggatg cgggctaaag tagatactat tgcccgccgc caacatgctg
    14341 atgctgttat taatgatggt ttccgtcggg ttggtgcttg gggcgactga accgatgacg
    14401 ccaaacggcg agtattcaaa gagtaccatg ccgccgtcac cggtcagcgc ggtggtggtg
    14461 agatcttcta cgcccggcgt gttgtccaga gcagccttgt ttttgaggaa tttatcttct
    14521 ttgttgccca ttcccgtttc attggcgctc tcctctgcca gagcagccag cagcggcgtc
    14581 agctcctgac gcatcgcgct gataatggcg ctgcgggttt ttagcgggca ctgctgataa
    14641 cgtaagaacg cctgatgcgc ggcgtcgatg gcctcgctca cggactggaa aatccctttg
    14701 ccctgaggct gggccggtgt ttgcgctggc gtggttaatt gctcgctaag aatggtgcga
    14761 atcagggttt cgagttcaga agtattcatt gatgtgttcc cacgttaata gccgcgatgg
    14821 cggtctgtgc tatgtccatg tcctgctcaa cgctgccgcc actgatgcca agacccccaa
    14881 ttaatatgcc gtcgcgccat agggcgtaac cgccgccaaa ggtgaccact tttccctgta
    14941 aatgactttc cagaccgtaa agcgccgcgc ctggctgaac gacatcgctc agctcatggg
    15001 tcgccgtttt catcgccact gcggtccatg cctttttcgg tgccagttcg ctgctgacca
    15061 gcagggcgtc cggcatccgc caggtcacag tttccgtgcc gtgcgcgtca acgatgctga
    15121 cgactaccgg aacctgcagt tgctgcgcgc gttcaacggc ggcgcgggtg agctggtgca
    15181 gatcgtggaa tgagagggcc acgggcgttg tctccttgct gcgggtcggc tggctggcag
    15241 ccagatagcg cttgctaact tcacggatga tgttggcctg gtgcgcatcg ctatcttccg
    15301 cgcgggccag ggcgtacagg cagtccgata agcggttgat gtagcgcatc agcacttggc
    15361 gtacgttgac ttcagttgcc agttcaacca gacggcgttc ggcgcggcgc gccagcgtgc
    15421 gggcaaaatg taatcggctc gcggcttcgc agcgtccggg taaaataaag ctgtgcagcg
    15481 gttcgacgcg ggccattgcc cgatcgatag cggcttccag ggccgaaatc tcttcgctgc
    15541 tgatgtagcg ctgtttgggc gatggctgct cgctgtcgct ggccagctct gcgctaaacc
    15601 aaaaaagttg ctgctggatg gcctcgagta aggtgcggtg attttcatcc gcagcggcgc
    15661 aggcgcacag gctcagcgcg gcgttcagtt catccagcgt gccgtaggct tcaacccgcg
    15721 ggtgggtttt gctcacccgc tggccggtaa acagtgatgt ggtgccagcg tcacctgttc
    15781 gggtataaat cgccataacc gccccttaac gcgaaagcgt atctacaatg ccgacaacgg
    15841 cgaggtcgat ggcctcattt ggcccggaaa aaacgtgcct ggcgctggag ccgccgctga
    15901 gcaaaaccag ttcgccgacg cccgcgccga cggagtccac ggccacttca tcgccggagg
    15961 tgggcgaggc ggggagttcg ccatcggcgc tgacccgacg caccagcagc agcttttccc
    16021 aatcaaagaa ggtgattttt gcgtggagac aaccgcgccc gtgactcgtg ccagatgcat
    16081 gatttactcc tgcttaatta attgaatatt ccgcgcattg gccgcgtcac gcgccatggc
    16141 ggtcacgatg catttgcggt ggacaaccac acgcccccgg cttagcagcg cgacatcgcg
    16201 atagcccagc accgaacccg catgcagaac cagcggcagt ccgtgctcgt cggtgaatac
    16261 cagcggcaga cgagccagtt tttttaccgg gataaccggc agcagctggc tgtgcaggct
    16321 gagctgtacg cggatgccaa acgccagcgc gtcgtgaatt ttccgggctg cggcatcgtc
    16381 ggtttctgca tccgcaagct gacccagcag cggcaggtcg acgagcagga tgcgcagcga
    16441 cgcgtgctga cagaacagcg ctggacagtc ggcatcgcga agctgcgcaa cgctcagcgt
    16501 tgccgtgctc agggcacgac gctgcagtcg ggagacaatc tcctcgacaa tgcgctgcag
    16561 agtttcgccg ttcatcgcgg gcctaccagc cgggcaaagg cctgcgggtt atcggcacca
    16621 gcggcgttgg cttcatcggt atcaatgtgc atttcgaggc gcatgtccgg tgaaacgcga
    16681 atcgccacat tgttgaaaat cagcccgcgc tcgtcgcctt caatcgctac cgaaacccta
    16741 tcgccgtggg agaccttcag gatcagcgca tcaagcggcg acatatgaat atgccgctgc
    16801 gcgacgataa ccccggaagg tagctccagt tcgccaaagg ggctgaccag gcggatgcca
    16861 ggtgtgccct tcaggttgcc ggacattctc agcggcgcgg caatccccag tgttctggca
    16921 tcggtacgcg atatttctac ctggcttacc gagcgcagcg ggccgagcag gcgcacattt
    16981 ttgagctgtc ctttcggccc taccagggtg acggtttgct ccgtagcata ttgtcccggc
    17041 tgcagtagcg cttttttttc gctgatggga tggccgggaa acagccgctc ataatcctgc
    17101 gcggacaggt ggatatgacg gtttgagacg cccagcggaa taggccgctg gcgcatctcg
    17161 tcgagaactt tacggaccgt tgattgcaga agctctttat ccattacgct tcacctcgct
    17221 tgccggaatg aatgcaaagc gtacgaggtt cgcccttctg gcgcggacat tttggatcca
    17281 gacacagatt gcagctgacc agttctgatt cctgcggggc ctcttcggct ggcgcttcag
    17341 aaacgacatc agctatctct gacgcttcag gctcaggttc aatgacggag ggggagggtg
    17401 tctctgcgag caggatccct tctccgggcc tggcgataac cttgtgggcc accagaccat
    17461 tccgctgttc ggcaaattgc gcaccggtgg tgatggccgc ctgcacggag gccacatcac
    17521 cggcaatttt aatcaccatc cagcctgaac cattggtctt ttcgagggcg agcagcgtga
    17581 tagaagcgga tttcgccatg atatcggcgc agctgatagc cagtgccaga ccacaaactt
    17641 caagtaatcc cagtgattgc ttcacgcggt gctccttatt cgccatcgat taggctgatt
    17701 tcggtaaaat ggcctcaaca tcgctgtgcg gacgcgggat aacgtggcag gatttcactt
    17761 cacccacgac gcttgccgcc gcgctgccgg catctacggc tgctttaacc gcgccgacgt
    17821 cgccgcgaac catgactgta accaggccag aaccaatttt ttcgtagccc accagctgta
    17881 cgttggcgga tttaaccatg gcgtcggcag cttcaatggc gcctactaac ccttttgttt
    17941 caaccagtcc cagtgcgtta ttcatactgc agttctcctg ttgcttagct attcagatcc
    18001 cggaaaggga tccctttgac cagccgtgcc gcgttattac cggtgttgcg ttgggcctga
    18061 ctgtcctgat gatgcatcag cgtaaaaagc ggcgccgatg cgggtaaatt cttgtaatgt
    18121 acgaccagcg agtgtcgatc gcaggcaatg ccgaccagca gcggcgagct gcgcgccgcc
    18181 tgccaggcgc tgtcaacgac atctccagct gggtgatgct gaagcaggaa agggatgcct
    18241 tcctcttcaa tgcccagcag cacttcgtgc cagaggctgg cgcagtcgtt gatgacggta
    18301 atgacgatag ccggggcgct gtgattactg tccatatgca aactccttgt gccaggagag
    18361 aatcagaccg gtggccaccg cgtttcttgg gccttcgctg ccgcgaatat ttcctcgccc
    18421 ggcgactagg cggtagtgcg ccagcgcatc ggtgaccaac tgcggaactt cgaaatccag
    18481 cgacgagccg ccgaccagca ccacgaacgg aatatcgcga atgttgccgg ttggactgac
    18541 ctgacgcagc gcgcgcaggg cgttggtgac aaagacgcgt tctttagcgc tgcggcgaat
    18601 ggcgcgcact ttttccagcg ctaagtcgcc gggaagcggc accagttcgt ccggtttcac
    18661 cacgcagacg cgggcgaaca ccgcaggagg cagcggcgtc gggaagaact ggacgctgcc
    18721 gtcctcgtgg cgtaagtgga acaggctttc gaccttagcc agcgggtatt ttttgatctc
    18781 ttccgccaga tagcggtctt ccagccccag ttcgcgggca ataatcatcg tgaccatgtc
    18841 gcctgccccg gcgagatggg tggcgatgat ttcaccttta gggttgatga tggaggcatc
    18901 ggtggagccc gcgccgaggt cgaggatcgc cagcggtcgg gtggtacccg gcgtggtcag
    18961 cgcgcccaga atggcggctt cagcctcagc gccgccgatc tgcacgtcga tattaagctt
    19021 ctgctcaatt tcacgggcaa tcatcgccat ttgcagacgg tctgatttca ccatcgaggc
    19081 gatgccgacg gcctgctcca gcgagaactc cccggccaga ccgccggtga cgctcaccgg
    19141 aaccgaggtg tcaacggcca gaagatcctg aatgaaaatc tcgctgctcg gcttattggt
    19201 tagctcggcc atggtctggc gcacatgctc cagcatgccg ccgatattgg tcccggcctc
    19261 gccgttgacg ttgtcgagct tgccgtagcc gtccaccgct ttcatgatag cttcggcacc
    19321 ggcggcaaca tccacgcgca cggtacgacc ctgagcctgc agctccaggt taccggcggg
    19381 tattgcgcgc gctttgacgt cgccggatgg cgttttaacc accacggcgg aacggttgcc
    19441 aatcagcgcg cgcgccatcg ggacgatgtt tttcgtctca tcggcgttga ggttgaatac
    19501 ggtggcgatg ccgtaagggt tagagagggt ttcgataacc tttcccggca cggcgacttc
    19561 aatcgccgcc agcatcccca gcggaatgca gtcgatgtac agaacttcat cgacaatcgg
    19621 tagcgatttt tccagccggt tgctgaccag tacgccatcg tcgcgctgca aaatgacgcc
    19681 ggtaatctgg tatccggcgc gcattgaggc gttgataaca ttggcgatat cagcaaaatc
    19741 aaaggctgac gataccacca gaatatagga cgagtccgcc gggcgggtta acagctcctc
    19801 cggcgtaatc gtgataccca caccaaggcc tgctccgccc ggcgtttttg ggttatggcc
    19861 gatcattgtc gattcggtga tgatggtttc ggtaatggtt tccatcgcca catcgccaat
    19921 caccggcgtg gcttcgttaa tgcggatgag cgaaatatcg ctgacattga tccccgcgcg
    19981 ctttgcgacg agggcgagcg cttcctgaat gccgaacacg ttacgcaacg tgcctttgat
    20041 cccggtgttt tccgccagcg cgctgtgtgt aatcgttagt gcgccagtct catcttgccg
    20101 cgccagtgcg acttccgttg atgagttacc gatgtcaatg ccagctatat atcgcatcgt
    20161 atatcctttt tctcgtcgta cttcaaactg cctttttgtt ggctgcgttc tttcacccga
    20221 atcacttact acagtaagct catcggggtt atgagggaca tccctgtccc tcactaaagc
    20281 cagcctatgg ctgttcaaat tcgttccaga cgaatttgtc actcacttgc cgcctcaatg
    20341 catctcgaat tacttagaga aagctaatcg tcgcctttga gttttttacg ctcaacgtac
    20401 agccctgccg cttcacgaac gaaagctgcg caaatctttg cctgataacg gttttcgaga
    20461 tcgtcggcga tagcgagcag ctcttctttc gttgaacgat acggacgaag ggcgttgtag
    20521 atttcaagaa tgcgatcgtc cggtaccgcg gtcagttcgg cggcgcgttc gaagttcatc
    20581 gccagccggt cgcggcccgc atctttggcg atagacgcct gtaagcgcag ggttttcggg
    20641 gtaatacgca tatcctgagc ggtgacttta ttgctcagca cgttttccag cgtaaagtcg
    20701 tccagcgttt tattggtggc ggttttcacc cattccgggt gtttgttcgc cagcgggtag
    20761 tcgctgacct ttgcgctgcg ggacgtgccg cctgccgcag gagccgctgc tggcgcatcg
    20821 ccctgcaggc tgttcatgcg gctcaatacg tcccggacca tcgattcaat tgcgtcggta
    20881 ttcatggagt tatcctttat caaagcgtca cgcgcagttc ctgcgggttt ttgcccgtca
    20941 cgacgtactt ggtctcttta atgtgcaaaa tggccgactt tgcctggtac ttcgggcgtg
    21001 ccatctggtc atttagcgta gggaccggct gcggtgattc gcgtttcgca tagcgggcgg
    21061 cgtttttacc aatctgacgg taggtttcca gcgtcagcag cggcgcctgc gggaacagct
    21121 ccaggttgga gagcggcggt agcccctgct ggtggataac cgtagtatct ttcgactgga
    21181 tgccgatgga gatgccggag ccgctcaggc ggttaccttc aacggcgacg aacgccacgt
    21241 cggaagattt aaagcagcga atcacgcgcg ccctgatacc ttcttcttca ataccggcaa
    21301 tgacttcgcg caggatgctc ttatgcggta agccgacgat attaacagtc tgtgccaggc
    21361 caaatgccgg gccgacggcg ataatgactt cgtcctgctg agtgccctgg cgtgcttcgc
    21421 ccacttcggt cagaaagccg tcgcccgcag gcgcagcggt ctgtggtgct gtggatgccg
    21481 caggcgtatt aaacgagacg ggtttatcgc tgcccttcat atcgcggagc acgtcttcaa
    21541 ttatctggcg cagcaatttt tcattaattt ccatttctca ccccttaatc aatctcgttg
    21601 ggatcaagag cgccagggat gtttttaatc tcttcccagc gttctccctg caggcgataa
    21661 cctgttgccg gaccggcata gtcattgacg tcattaaccg cagagagcac ttgtccgtcg
    21721 ccgacgataa tggcggaggt gtgcaaatag tcgccggtta gcttggcttt ctggatgttg
    21781 agcatgtcct gggccacgtc ggtaaacccg ccctgcgcca gcgctttaac gacttccaga
    21841 ccgttgcggt ttttattgat gatttcctgg gcgaacttga tgtcttcgac gatgttacgc
    21901 tccggcatat ctttcgaacc gtgggcatag gtcgcggctt caacttcttc atcggtaatc
    21961 ggcggcagcc ccattccggc aaacacggcc tgcagcgcgc gggcggcttt gttacggatg
    22021 gcgataacgt cctcttcacg aaccgggcgc agaccgccgt ccactttcag gtcgcgctgg
    22081 ataacgttgt agtcgtcaaa gtcttccgca tcttcgttgg aaccggcgaa catgttgtcg
    22141 tagttcggca ccgcggaata accagaggag ataaagtcgg tacccggcag gaactgcatc
    22201 agcaggcgcg cggtacgacg catatcggag tgggtgaagg tctggtcgtt actggaggag
    22261 cattccagat ccagcgaaga gcagatcagg ttttccgcca gcacggcacg aatgcctgac
    22321 ggcacggcag acggtacgcc gatacagctt acggagccat tttgcagacc ctgaacgcca
    22381 gccgctttgg tgatatagat gcagcgcgcc tccagataca gcatggattt gccttcggcg
    22441 tagcccatct gcacttcgga tccggagccg gaggtgaagc gcattttcag gccgcgagag
    22501 gcgtaggaag aggctaagaa gcctttcgac catggcgtat cgtcaccgtc ggtgaagacc
    22561 ggctcggtgc cgtaaacgga aatggtttcg gcgtagcagg tgtggcccag catgccgagc
    22621 ttcagctcgg tggcttcttc cagggagcac tgagtcagta cgcccggacg accaacctga
    22681 gagccgacca acagcgcgat ggcgttgaac ggcgcgtagc gtgctaccgc aaccgtggtt
    22741 tcttgttcgt caaacccgcg ccatgcgcct tcggcggcat cggcggcaat ttgcaccggg
    22801 ttatccttga cgttggtgac gtgcgcctgc tgagacggcg tgcggcgtgc gcgcattttc
    22861 tgcatcgcca tcatcatctc aaccacgttc atatgcgaaa ccacttcaac aattttcgcc
    22921 ggggtcatgg cggtggtcag cggaacgatt tcgctgcgct tgacgttcgg atcgcagagc
    22981 atgttagcca gcttgaccga atccatcgcc atcacttctt cggcgcggtt caggttgatg
    23041 ccgtagcggg cgataaagtg gtcgatcagg tcgaattcgc taaccggttt tccgtccagc
    23101 tcggtcaccg cgccgttaac gattttaatc gacggttttg gatcgttcgg gctttccatc
    23161 gcgataaagc cttcttcgat ccactcctta acgaagccgt cctgattcac agggcgtttc
    23221 gccagtgctt caaatctttt cgatctcatg aatcagcctc gtgggtatca gatgtaggac
    23281 gggcgatcgt ttttcggttc agaaccgagg gtcgcaagga cggttttgcc gatttcgcgg
    23341 gcggaggtca ccgcctgacg gaccgcgccg gagtcgccgg aaatcaccag aatggcttcg
    23401 ttactaaagc tggtgccgtg cgccggagag ctgtacgcca cgacttcaac gttggctgac
    23461 ttcagggcgg tatcggccat cagtacgcca acggaagccg gagcgccgac gatgacgccg
    23521 caggcacggc caatcggcgc gccgaacgct ttttccaggg cgtagctggc gcgagcggtg
    23581 tactgcagct cgatatgccc ggcttcgttg ccgtaaacat cgccgaaggt gcggtccagc
    23641 tctttcagcg cgacttcgat accgcgcttg acgtcggaaa cgtcgttacc gcctaaaata
    23701 atcagcgaac cgtggcccgc gccgcctttg gtatcgcgcg gcagctcaat gctgaccact
    23761 tcggtgttgg tggctttcac cgcttcgtcc gccgccataa tgtgcgggcc tgcgccggtg
    23821 cgggcgccga gaatgccgat ggaacgatag cgcttctcaa gtttcatcgc gtccagcagg
    23881 gcggtatcga cgttggcgat aaccaggcca agggtatcgc caatggcggt cccgacaaat
    23941 tccgttaaac tgcagctttt ttctgccata gccgtctctc gtataggttg gggttgacca
    24001 gggatggcct gttgttccgg cgttgccaca cgggcaatca cctgcgccat gatctgttcc
    24061 accagctcat tgctgctcat tggctaattc ccttcggtaa gattttttct acatcggtgt
    24121 gagggcgtgg gatgacgtgt acggctttca cttcacccac gttgcgtgcg gctgcggcac
    24181 ctgcatcggt ggccgctttg accgcgccaa catcgccgcg cacgatgacg gttaccagcc
    24241 cggagccaat cttttcatag cccactaaca tcacattggc tgacttaacc attgcatcag
    24301 cggcctctat ggctgcggtt aagcctttgg tttctaccat tcctagtgct tcttgttgca
    24361 taaagacctc gcatggagtg ttccgatagt tgggactata agaagatgcg aggaaaaaga
    24421 atggctgact tgctgttgag catcagaaaa taatgggaaa gcaatatgac taaattgtct
    24481 tttgctttta taacttattg ataaattaca tttaatttat tattgtctat atgattattt
    24541 tgtttttatt atttcatttt tacatttttg ttagtgacga gagtattttt atttgatatg
    24601 gcgaaagacg caaaatgtga tgcttattcg aaattgataa gttggcttgt gcaatatttt
    24661 attattttca caggcgtatt ttatagctcg aatctcccgt atgataggct gctaaaaata
    24721 tcggaaaagc aaaattttgc tatcgcaaca cgatttttcc gggagacagg ttcgcaggtt
    24781 gccaacaatt tacaggcggc actttttata gtgaggttag ctgtactcta ccgccagccg
    24841 aaacttgcgc tggtcaggac acgaactttg ctcagaaggt gtcacatgaa tgattctcta
    24901 aaggcgcaat gtggtgcgga atttttaggc accggactct ttttgttttt tggtatcggt
    24961 tgtttgagcg cgctcaaagt cgcaggcgcc agcctcggat tatgggagat ttgcattatt
    25021 tgggggcttg gaatttcact ggccgtttac cttactgccg gaatctccgg cggacatctt
    25081 aaccctgcgg tgacgattgc gctgtggctg tttgcctgct tccccaaaca gaaagtattg
    25141 ccttatatta ttgcccagtt tgccggcgct tttggcggcg atctgctggc gtatgtgctt
    25201 tatagtagcc tttttactga atttgagact gcgcatcata tggtgcgcgg tagcgtcgaa
    25261 agtttgcaat tagccagcat tttcagtacc tatccggccg cagcgctaaa tgtatggcag
    25321 gctgcgttgg tggaagtggt cattacgtcg atcctgatgg gcatgatcat ggcattgacg
    25381 gatgatggca atggtattcc taaagggccg cttgcgcctt tgcttattgg gatactggtt
    25441 gccgttatcg gcgcgtctac tggacccctt accggttttg caatgaaccc ggcgcgtgat
    25501 tttggtccca aactgttcac atggttagcg gggtggggga acatggcgat gagcggtggg
    25561 cgagagatcc cttattttat cgtgccgatt gtcgcgcctg ttatcggcgc ctgtgctgga
    25621 gcagccatat atcgctattt tattggtaag aatttacctt gtaaccgctg taaactgtaa
    25681 gaaaatgcga accagattca cagcaatgat gtatcgtaaa aacaggtgag ataatttcgt
    25741 gatctgcttt cacgaactga tcaaaacgtc tcccagcaat gggagacttt tgatattgtc
//
LOCUS       DAJVBX010000041        25717 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.041, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000041 DAJVBX010000000
VERSION     DAJVBX010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 25717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25717
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.041"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..714
                     /locus_tag="OPV72_001505"
     CDS             <1..714
                     /locus_tag="OPV72_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4311 domain-containing protein"
                     /protein_id="HCR9913853.1"
                     /translation="AGAARMFHAPTTQGMGAFRTLGELNSCEGDPASHFSFGLGFFFN
                     AWASSVAAGSFTQDVDHRIIPNWGAAALMIKNRNVGETLHDPKKMAIACAVIGMIVVT
                     FLNLTASSVPEALQVTAVKVLVPAANLLVNIVMPVIFWLAAIDAGKKSGFWATVFGGA
                     AQLIMGNAVPGLVLGILIGKGVEESGWNHVTKVMMVAIVLLFVLSGFFRGFDMKMIES
                     FNMTVPNWLELIHNSLSGK"
     gene            726..1370
                     /locus_tag="OPV72_001506"
     CDS             726..1370
                     /locus_tag="OPV72_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4310 family protein"
                     /protein_id="HCR9913854.1"
                     /translation="MEENKGFWYADWSFPIFVGLLSSGVFAGTHMYYLYGIGAFNEVA
                     FVAMLKAGMDTGVYGAVAAFGASFLFARIIEGSLVGILDIGGAIQTGVGLGVPALLLG
                     AGFVFPVANFIASLITGLVIGLAIGYIIILARKFTINQSDSTYGADVMMGAGNTSGRF
                     LGPLIILSAMTASIPIGLGSLVGALLFYIWQKPITGGAILGAMILGSIFPVSIS"
     gene            1429..2562
                     /locus_tag="OPV72_001507"
     CDS             1429..2562
                     /locus_tag="OPV72_001507"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase/deacetylase family
                     metallohydrolase"
                     /protein_id="HCR9913855.1"
                     /translation="MFDLLLRHARLVDDTLTNIALQDGKIAALGDVDGPALKTIDLRG
                     ECYVSAGWIDSHVHCYPKSPIYHDEPDSVGIATGVTTVVDAGSTGADDIDDFYTLTRD
                     AATEVYALLNVSRVGLIAQNELANMANIDADAVRQAVKRHPDFIVGLKARMSSSVVGV
                     NGITPLERAKAMQQENGNLPLMVHIGNNPPDLDEIAERLTAGDIITHCYNGKPNRILR
                     PDGELRASVTRALARGVRLDVGHGTASLSFAVAKRAISLGILPHTISSDIYCRNRING
                     PVHSLANVMSKFLAIGMSLPQVIACVTANAADSLNLKTKGRLQPGLDADLTLFTLKRQ
                     PTVLVDAENDSLQAEELLTPLAAIRAGKGYMTEQGSAEHAFDF"
     gene            2546..3664
                     /locus_tag="OPV72_001508"
     CDS             2546..3664
                     /locus_tag="OPV72_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgaE family pyridoxal phosphate-dependent
                     ammonia lyase"
                     /protein_id="HCR9913856.1"
                     /translation="MPSIFEKYQLKQVINASGRMTALGVSTPRPEVIDAAMAGMNQYF
                     EMKDLVNKTGEYIAKLLEVEGATVVSCASAGLAQSVAAVLVQDSDWLLENLHVTPIEN
                     NEIVLPKGHNVNFGAPVGTMVALGGGKLVEAGYANECSAAQLAAAITPRTAAILYIKS
                     HHCVQKSMLSVEQAAVVARTHNLPLIVDTAAEEDLQCYYRVGADLVIYSGAKAIEGPT
                     SGLVIGKTQYVEWVKRQSAGIGRAMKVGKEGIVGLTCAIELYLRAQKESGAEMVEKMA
                     PFIDTLNTFNGVSARVVWDSAGRDIARTEIKFDEAVTGIATGDLVDALKQGEYAIYFR
                     GYKANEGIIEADVRSVDRAQLAIVARRIGEVINQEKQA"
     gene            3661..4401
                     /locus_tag="OPV72_001509"
     CDS             3661..4401
                     /locus_tag="OPV72_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463308.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KDGP aldolase family protein"
                     /protein_id="HCR9913857.1"
                     /translation="MKLTPNFYRDRVCLNVLAGSKDNAREIYAAAEGHVLVGVLSKNY
                     PDVASAVADMREYAALIDNALSVGLGAGDPNQSAMVSEISRQVQPQHVNQVFTGVGGS
                     RALLGQNETVVNGLVSPTGTPGLVKISTGPLSSRAPDGIVPIETAIALLKDMGGSSVK
                     YFPMGGLTCRDEYKAVADACARHDFWLEPTGGIDLENFAEILHIALDAGVSKIIPHIY
                     SSIIDKVSGNTRADDVRQLLAIVRSRVG"
     gene            4418..6331
                     /locus_tag="OPV72_001510"
     CDS             4418..6331
                     /locus_tag="OPV72_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HCR9913858.1"
                     /translation="MRFPNQRLAQLFAMLQNETLPQDELAQRLSVSTRTVRADIAALN
                     MLLTPHGAQFTLSRGNGYQLKIDDPARYQSLQTQQSPTLARGPRTSQERIHYLLARFL
                     TSAFSLKLEDLADEWFVSRATLQNDMADVREHLLRYHLTLETRPRHGMKLFGGEMAIR
                     ACLTDLLWTLVQQEPSHPLIVSTTLNTEVSQRLQSLLPDIFSHCQIRLTDEGELFLRL
                     YCAVAVRRIREGYPLSECVAEEVDEKVRHAAHEIAELLQQLADKPLSEPEVSWLKVHI
                     AARQVQEIAPSAINADDEEALVHYILNFINTQYNYNLLNDKQLHADLLTHIKTMITRV
                     RYQIMIPNPLLENIKQHYPMAWDMTLAAISSWGKYTPYTISENEIGFLVLHIGVGLER
                     SYNIGYQRQPQVLLVCDAGNAMVRMIEAVLARKYPQIEIARTLTLRDYEARDSMVEDF
                     VISTARIGEKDKPVIMIAPFPTDYQLEQIGKLVLVDRTRPWMLDKYFDASHFRIVEGE
                     INQQTLFKTLCDQLHEEGFVDAAFLDSVIEREAIVSTLLGDGIALPHALGLLAKKTVV
                     YTVLAPQGIAWGDETAHVIFLLAISKSEYEEAMAIYDIFVTFLRERAMTRLCACQNFT
                     QFKTVAMECVSRF"
     gene            6409..6651
                     /locus_tag="OPV72_001511"
     CDS             6409..6651
                     /locus_tag="OPV72_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HCR9913859.1"
                     /translation="MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAETGRM
                     PVKTVTLSDSEDALIQTVRERLSSPQKGIKVSLDDL"
     gene            6641..6925
                     /locus_tag="OPV72_001512"
     CDS             6641..6925
                     /locus_tag="OPV72_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HCR9913860.1"
                     /translation="MTYELEFDPRALKEWHKLGDTVKAQLKKKLADVLLNPRIDSARL
                     NGLPDCYKIKLKSSGYRLVYQVRDDVVIVFVVAVGKREHSAVYHDANKRL"
     gene            complement(6929..7393)
                     /gene="nrdG"
                     /locus_tag="OPV72_001513"
     CDS             complement(6929..7393)
                     /gene="nrdG"
                     /locus_tag="OPV72_001513"
                     /EC_number="1.97.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate
                     reductase-activating protein"
                     /protein_id="HCR9913861.1"
                     /translation="MRYHQYYPVDIVNGPGTRCTLFVSGCVHECPGCYNKSTWRLNSG
                     QPFTKEMEDKIIADLNDTRIHRQGISLSGGDPLHPQNVPDILALVQRIHAECPGKDIW
                     VWTGYRLDELNAAQMQVVNLINVLVDGKFVQDLKDPALIWRGSSNQVVHHLR"
     gene            complement(7514..9652)
                     /gene="nrdD"
                     /locus_tag="OPV72_001514"
     CDS             complement(7514..9652)
                     /gene="nrdD"
                     /locus_tag="OPV72_001514"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HCR9913862.1"
                     /translation="MTPHVMKRDGCKVPFKSERIKEAILRAAKAAGVDDADYCATVAE
                     VVSSQMNARSQVDINEIQTAVENQLMSGPYKQLARAYIEYRHDRDIQREKRGRLNQEI
                     RGLVEQTNSALLNENANKDSKVIPTQRDLLAGIVAKHYARQHLLPRDVVQAHERGDIH
                     YHDLDYSPFFPMFNCMLIDLKGMLTQGFKMGNAEIEPPKSISTATAVTAQIIAQVASH
                     IYGGTTINRIDEVLAPFVTESYNKHRKTADEWQIPDAEGYARSRTEKECYDAFQSLEY
                     EVNTLHTANGQTPFVTFGFGLGTSWESRLIQASILRNRIAGLGKNRKTAVFPKLVFAI
                     RDGLNHKFGDPNYDIKQLALECASKRMYPDILNYDQVVKVTGSFKTPMGCRSFLGVWE
                     NENGEQIHDGRNNLGVISLNLPRIALEAKGDETAFWKLLDERLALARKALMTRIARLE
                     GVKARVAPILYMEGACGVRLKADDDVSEIFKNGRASISLGYIGIHETINALFGGEHLY
                     DSEQLRAKGIAIVERLRQAVDQWKDETGYGFSLYSTPSENLCDRFCRLDTAEFGVVPG
                     VTDKGYYTNSFHLDVEKKVNPYDKISFEAPYPPLANGGFICYGEYPNIQHNLKALEDV
                     WDYSYQHVPYYGTNTPIDECYECGFTGEFECTSKGFTCPKCGNHDAARVSVTRRVCGY
                     LGSPDARPFNAGKQEEVKRRVKHLGNGQIG"
     gene            complement(10061..11713)
                     /gene="treC"
                     /locus_tag="OPV72_001515"
     CDS             complement(10061..11713)
                     /gene="treC"
                     /locus_tag="OPV72_001515"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HCR9913863.1"
                     /translation="MTIPLWWQNGVIYQIYPKSFQDTTGSGTGDLRGVTQRLDYLQRL
                     GVDAIWLTPFYISPQVDNGYDVANYTAIDPTYGTLDDFDELVAQAKARGIRIILDMVF
                     NHTSTQHAWFREALNKESPYRQFYIWRDGTPDVCPNNWQSKFGGSAWRWHSQSEQYYL
                     HLFAPEQADLNWENPAVRAELKKVCEFWADRGVDGLRLDVVNLIAKDQDFPDDPTGDG
                     RRFYTDGPRTHTFLREMNRDVFTPRNLMTVGEMSSTTLENCQQYAALSGDELSMTFNF
                     HHLKVDYPNGEKWTLAKPDYVALKALFRQWQQGMHNVAWNALFWCNHDQPRIVSRFGD
                     EGEYRVPAAKMLAMALHGMQGTPYIYQGEEIGMTNPHFTRITDYRDVESHNMFAALRA
                     AGRDPDELLAILASKSRDNSRTPMQWDNGKNAGFTQGEPWISLCDNYTEVNVAAALRD
                     ENSVFYTYQKLIALRKTQPVMIWGDYQDLLPGSPSVWCYRRQWQGQTLLVVANLSDQC
                     QEWHPPHIKGQWQALLHNYGEVASQPAAMTLRPFEAIWWLQR"
     gene            complement(11763..13181)
                     /gene="treB"
                     /locus_tag="OPV72_001516"
     CDS             complement(11763..13181)
                     /gene="treB"
                     /locus_tag="OPV72_001516"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005224799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS trehalose transporter subunit IIBC"
                     /protein_id="HCR9913864.1"
                     /translation="MSKVKQADIDRLIDLVGGRDNIATVSHCITRLRFVLHQPANARP
                     KEIEQLPMVKGCFTNAGQFQVVIGTEVGDYYNALLETTGKAYADKEQAKKAARQNMKW
                     HEQLISHFAEIFFPLLPALISGGLILGFRNVIGDVPMSHGQTLAQMHPALKTLYDFLW
                     LIGEAIFFYLPVGICWSAVKKMGGTPILGIVLGVTLVSPQLMNAYLLGQQTPDVWNFG
                     VFSIEKIGYQAQVIPALLAGLALGFIETRLKRIVPDYLYLVVVPVCSLILAVFLAHAF
                     IGPFGRMIGDGVAFAVRYLMTGSFAPIGAALFGFLYAPLVITGVHQTTLAIDMQMVQS
                     MGGTPVWPLIALSNIAQASAVVGIIISSRKHNEREISVPAAISAYLGVAEPAMYSINI
                     KYRFPMLCAMIGSGLAGLLCGLNGVMANGIGVGGLPGILSIQPTYWQVFAMAMVIAIV
                     IPVILTTFIYQRKHRQGTLQIV"
     gene            complement(13319..14266)
                     /gene="treR"
                     /locus_tag="OPV72_001517"
     CDS             complement(13319..14266)
                     /gene="treR"
                     /locus_tag="OPV72_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator TreR"
                     /protein_id="HCR9913865.1"
                     /translation="MQNRLTIKDIARLSGVGKSTVSRVLNNESGVSKRTRERVEAVMN
                     QHGFSPSRSARAMRGQSDKVVAIIVTRLDSLSENLAVQTMLPAFYEQGYDPIMMESQF
                     SPMLVMEHLGMLRRRNIDGVVLFGFTGITEELIAPWKASLVLLARDAQGFASVCYDDE
                     GAIHILMQRLYEQGHRNISFLGVPHSDITTGKRRHDAYLAFCKKHKLHPVAALPGLAM
                     KQGYEHTASVIMPDTTALVCATDTLALGASKYLQEQRIETLQLASIGNTPLIKFLHPE
                     IVTVDPGYAEAGRQAALQLIEQINGRCDPRRIVIPSTLA"
     gene            14411..14509
                     /gene="mgtL"
                     /locus_tag="OPV72_001518"
     CDS             14411..14509
                     /gene="mgtL"
                     /locus_tag="OPV72_001518"
                     /inference="COORDINATES: protein motif:HMM:NF028369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mgtA regulatory leader peptide MgtL"
                     /protein_id="HCR9913866.1"
                     /translation="MRIIRGANYLLTGGDMDPEPTPLPRWRIFLFR"
     gene            14650..17358
                     /gene="mgtA"
                     /locus_tag="OPV72_001519"
     CDS             14650..17358
                     /gene="mgtA"
                     /locus_tag="OPV72_001519"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HCR9913867.1"
                     /translation="MLKTITRQLFARLNRHLPYRLVHRDPLPGAQTAVNATIPPSLSE
                     RCLKIAAMEQETLWRVFDTHPEGLNAAEVTRAREKHGENRLPAQKPSPWWVHLWVCYR
                     NPFNILLTILGGISYATEDLFAAGVIALMVGISTLLNFVQEARSTKAADALKAMVSNT
                     ATVLRVINENGENAWLELPIDQLVPGDIIKLAAGDMIPADLRIIQARDLFVAQASLTG
                     ESLPVEKVATTREPRQNNPLECDTLCFMGTNVVSGTAQAVVMATGADTWFGQLAGRVS
                     EQDNEQNAFQKGISRVSMLLIRFMLVMAPVVLIINGYTKGDWWEAALFALSVAVGLTP
                     EMLPMIVTSTLARGAVKLSKQKVIVKHLDAIQNFGAMDILCTDKTGTLTQDKIMLENH
                     TDISGKPSEHVLHCAWLNSHYQTGLKNLLDTAVLEGVDETAARQLSGRWQKIDEIPFD
                     FERRRMSVVVAEDSNVHQLVCKGALQEILNVCTQVRHNGDIVPLDDNMLRRVKRVTDT
                     LNRQGLRVVAVATKYLPAREGDYQRIDESDLILEGYIAFLDPPKETTAPALKALKASG
                     ITVKILTGDSELVAAKVCHEVGLDAGDVVIGSDIEGLSDDALAALAARTTLFARLTPM
                     HKERIVTLLKREGHVVGFMGDGINDAPALRAADIGISVDGAVDIAREAADIILLEKSL
                     MVLEEGVIEGRRTFSNMLKYIKMTASSNFGNVFSVLVASAFLPFLPMLPLHLLIQNLL
                     YDVSQVAIPFDNVDEEQIQKPQRWNPADLGRFMVFFGPISSIFDILTFCLMWWVFHAN
                     TPETQTLFQSGWFVVGLLSQTLIVHMIRTRRLPFIQSRAAWPLMAMTLLVMVVGVSLP
                     FSPLASYLQLQALPLSYFPWLIAILAGYMTLTQLVKGFYSRRYGWQ"
     gene            complement(17474..17920)
                     /locus_tag="OPV72_001520"
     CDS             complement(17474..17920)
                     /locus_tag="OPV72_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCR9913868.1"
                     /translation="MVRARFTEEQIADFLQQSKNGVPNKALCEEYGFSNSTLRRWQEK
                     HAESIRQELKQIESTAKIVFLCFIIAAILLTLMFPKPTAALAIPPYLVYCISYIRRFR
                     RISAKHIQRWDISSSRSGSGAENVFYKLSWTFLFFMPAYSILQLLE"
     gene            complement(17995..18381)
                     /gene="ridA"
                     /locus_tag="OPV72_001521"
     CDS             complement(17995..18381)
                     /gene="ridA"
                     /locus_tag="OPV72_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminobutanoate/2-iminopropanoate deaminase"
                     /protein_id="HCR9913869.1"
                     /translation="MSKTIATENAPAAIGPYVQGVDLGSMVITSGQIPVDPKTGAVAE
                     DVSAQARQSLENVKAIVEAAGLKVGDIVKTTVFVKDLNDFATVNATYEAFFTEHNATF
                     PARSCVEVARLPKDVKIEIEAIAVRR"
     gene            complement(18458..18919)
                     /gene="pyrI"
                     /locus_tag="OPV72_001522"
     CDS             complement(18458..18919)
                     /gene="pyrI"
                     /locus_tag="OPV72_001522"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase regulatory
                     subunit"
                     /protein_id="HCR9913870.1"
                     /translation="MTHDNKLQVEAIKCGTVIDHIPAQVGFKLLSLFKLTETDQRITI
                     GLNLPSGEMGRKDLIKIENTFLTDEQVNQLALYAPQATVNRIDNYDVVGKSRPSLPER
                     INNVLVCPNSNCISHAEPVSSSFAVKKRANDIALKCKYCEKEFSHNVVLAN"
     gene            complement(18932..19867)
                     /gene="pyrB"
                     /locus_tag="OPV72_001523"
     CDS             complement(18932..19867)
                     /gene="pyrB"
                     /locus_tag="OPV72_001523"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HCR9913871.1"
                     /translation="MANPLYQKHIISINDLSRDDLNLVLATAAKLKANPQPELLKHKV
                     IASCFFEASTRTRLSFETSMHRLGASVVGFSDSANTSLGKKGETLADTISVISTYVDA
                     IVMRHPQEGAARLATEFSGQVPVLNAGDGSNQHPTQTLLDLFTIQETQGRLDNLHIAM
                     VGDLKYGRTVHSLTQALAKFSGNRFYFIAPDALAMPQYILDMLDEKGMAWSLHGSIEE
                     VMADVDILYMTRVQKERLDPSEYANVKAQFVLRASDLNGARENMKVLHPLPRIDEITT
                     DVDKTPHAWYFQQAGNGIFARQALLALVLNSELSL"
     gene            complement(19903..20004)
                     /gene="pyrL"
                     /locus_tag="OPV72_001524"
     CDS             complement(19903..20004)
                     /gene="pyrL"
                     /locus_tag="OPV72_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyr operon leader peptide"
                     /protein_id="HCR9913872.1"
                     /translation="MVQCVRHSVLPRLKKDAGLPFFFPLKTNTKPLN"
     gene            19984..20125
                     /locus_tag="OPV72_001525"
                     /pseudo
     CDS             19984..20125
                     /locus_tag="OPV72_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_453732.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(20095..20584)
                     /locus_tag="OPV72_001526"
                     /pseudo
     CDS             complement(20095..20584)
                     /locus_tag="OPV72_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463323.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
     gene            complement(20771..22174)
                     /locus_tag="OPV72_001527"
     CDS             complement(20771..22174)
                     /locus_tag="OPV72_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HCR9913873.1"
                     /translation="MGKFKFPTAYTILFILIALVAVMTWIVPAGKYQMAMNATLGKEV
                     PVAGTYAPVDAHPQGITAVLLAPIDGLYNHETYTAGAIDVALFVLIIGGFLGVVNKTG
                     AIDAGIERVTIKLNGKDEWMIPILMALFAAGGTIYGMAEESLPFYTLLVPVMMAARFD
                     PLVATATVLLGAGIGTLGSTINPFATVIAANAAGIPFTQGMLMRVLLLIVGYVLCVFW
                     VMRYARKVRAHPELSIVADKMAENRAHFLGNRANTLLEFTATRKWVLLIFAASFAVMI
                     YGVAVLGWWMAEISGVFLAAAIIVGVITRMGEEAFTSTFIDGARDLLGVALIIGIARG
                     IVVVMDNGMITHTILHSAESLVSGLSTTIFINVTYWLEVLLSFLVPSSSGLAVLTMPI
                     MAPLADFAHVQRDLVVTAYQSASGIVNLVTPTSAVVMGGLAIARVPYVRYLKWVAPLL
                     LILTLLNMAVLSIGAMM"
     gene            complement(22230..23234)
                     /gene="argF"
                     /locus_tag="OPV72_001528"
     CDS             complement(22230..23234)
                     /gene="argF"
                     /locus_tag="OPV72_001528"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HCR9913874.1"
                     /translation="MVISLKNRNFLKLLDYTPAEIQHLIDLAIELKAAKKAGCEKQTL
                     IGKNIALIFEKTSTRTRCAFEVAAFDQGAQVTYLGPSGSQIGHKESMKDTARVLGRMY
                     DGIEYRGFGQHIVEELGEYAGVPVWNGLTDEFHPTQILADLMTMLEHAPGKTLPELSF
                     AYLGDARNNMGNSLMVGAAKMGMDIRLIAPKSFWPDAALVAQCREIASVTGARITLTE
                     SVEDGVHGVDFLYTDVWVSMGEPKEAWAERVSLMTPYQVNQQVVNATGNPDVKFMHCL
                     PAFHNEHTKVGREIEMAYGLKGLEVTEEVFESAGSMVFDEAENRMHTIKAVMVATLGD
                     "
     gene            complement(23346..24278)
                     /gene="arcC"
                     /locus_tag="OPV72_001529"
     CDS             complement(23346..24278)
                     /gene="arcC"
                     /locus_tag="OPV72_001529"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HCR9913875.1"
                     /translation="MENKRTLVVALGGNALLKRGEPLEADIQRKNIELAARTIAQLTR
                     QWRVVLVHGNGPQIGLLALQNSAYANVTPYPLDILGAESQGMIGYMLQQALKNHLPER
                     EISVLLTQVEVDANDPAFLNPTKYIGPIYDEAQARALQAEKGWVFKADGNAFRRVVPS
                     SQPKRIVENDAIRALISRDHLVICNGGGGVPVVEKADGYHGIEAVIDKDLSAALLASQ
                     IHADALLILTDVDAVYLDWGKPTQRPLAQVTPELLREMQFDAGSMGPKVTACAEFVSH
                     CCGIAGIGSLADGQAILAGEKGTLIRCETADVDA"
     gene            complement(24289..25509)
                     /gene="arcA"
                     /locus_tag="OPV72_001530"
     CDS             complement(24289..25509)
                     /gene="arcA"
                     /locus_tag="OPV72_001530"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HCR9913876.1"
                     /translation="MEKHFVGSEIGQLRSVMLHRPNLSLKRLTPSNCQELLFDDVLSV
                     ERAGEEHDIFANTLRQQGIEVLLLTDLLTQTLDVADAKAWLLDTQISDYRLGPTFAAD
                     IRAWLADMPHRELARHLSGGLTYGEIPASIKNMVVDTHDINDFIMKPLPNHLFTRDTS
                     CWIYNGVSINPMAKPARQRETNNLRAIYRWHPQFADGDFIKYFGDENINYDHATLEGG
                     DVLVIGRGAVLIGMSERTTPQGVEFLAQALFKHRQAERVIAVELPKHRSCMHLDTVMT
                     HIDIDTFSVYPEVVRPDVQCWTLTPDGRGGLKRTQESTLVHALETALGIDQVRLITTG
                     GDAFEAEREQWNDANNVLTLRPGVVVGYERNIWTNEKYDKAGITVLPIPGDELGRGRG
                     GARCMSCPLERDGI"
BASE COUNT         5732 a         6733 c         7213 g         6039 t
ORIGIN      
        1 gctggggctg cacgtatgtt tcacgcgcca accacgcagg ggatgggcgc gttccgtacg
       61 ttgggcgaac tcaactcttg tgaaggcgac ccggcatctc acttctcctt tggactgggt
      121 ttcttcttta acgcctgggc gtcgtctgtg gcggccggat cgttcaccca ggatgtcgat
      181 caccgcatca tccctaactg gggcgcggcg gcgctaatga tcaaaaaccg taacgtcggc
      241 gagacgctgc acgacccgaa aaaaatggcg atcgcctgcg ccgtcatcgg catgatcgtc
      301 gtgacgttcc ttaacctgac cgcctcatcc gtgccagaag cgctacaggt gacggcggtt
      361 aaggtgctgg taccggcggc aaacctgctg gtcaacatcg tcatgcctgt gattttctgg
      421 ttagcggcga tcgacgctgg taaaaaatcg ggtttctggg ccaccgtttt cggcggcgcg
      481 gcgcagctca tcatggggaa cgccgtaccg gggctggtgc tgggtatttt gatcggcaaa
      541 ggcgtagaag agagcggctg gaaccatgtc accaaagtga tgatggttgc catcgttttg
      601 ctgtttgtgt tgagcggttt cttccgcggc ttcgacatga aaatgatcga gtctttcaac
      661 atgacggtac cgaactggct tgaactgatc cacaactcgc tcagcggcaa ataacggaga
      721 ccacaatgga agagaataaa ggtttttggt atgccgactg gtcgttcccg atctttgttg
      781 gcctgctctc ctccggcgtt ttcgccggga cgcatatgta ctatctgtac ggtatcggcg
      841 catttaacga agtcgctttt gtggcgatgt tgaaagcggg gatggatacc ggcgtctacg
      901 gcgcggtcgc cgctttcggc gccagctttt tatttgcccg cattatcgaa ggttcgctgg
      961 tcgggattct ggatatcggc ggggcaattc agactggcgt gggcttaggg gttccggcgt
     1021 tactgctggg ggctggcttt gtcttcccgg tggcgaactt tatcgcttcg ctgataaccg
     1081 gtctggtgat tggcctggcg attggctaca tcattattct ggcgcgtaag ttcactatta
     1141 atcagagcga ctccacgtac ggggcggacg tcatgatggg ggccggtaac acttcaggcc
     1201 gttttctggg gccgttgatt atcctcagcg ccatgacggc atcgattcct attggtctgg
     1261 gctctctggt gggcgcgctg ctgttttata tctggcagaa gccgattacc ggcggcgcga
     1321 ttttaggcgc gatgatcctc ggttccatct tcccggtttc gattagctaa ctgttgattt
     1381 gtaggtcgga taaggcggtt gcgccgccat ccggcaaagg agagaacgat gtttgattta
     1441 ctcctgcgcc atgcgcgtct ggtcgatgac acgctgacta atattgccct tcaggatggc
     1501 aaaatcgcgg cgttgggtga cgttgatggt ccggcgctga aaaccattga cctgcgcggc
     1561 gaatgttacg ttagcgcggg ttggattgat tctcacgttc actgctaccc gaaatcgccg
     1621 atttaccacg acgaaccgga cagcgtgggt attgccactg gcgttaccac agtggtggat
     1681 gcaggcagca caggcgctga tgatattgac gatttttaca cgctgactcg tgacgcggcc
     1741 accgaggttt atgcgctgct gaatgtttca cgcgttgggc ttattgccca aaacgagctg
     1801 gctaacatgg ccaatattga cgctgatgcg gttcggcagg cggtaaaacg ccatccggat
     1861 tttatcgtcg gcctcaaggc gcggatgagc agcagcgtgg taggcgttaa cggcatcacg
     1921 ccgctggaac gcgctaaagc catgcagcaa gaaaacggca acctgccgct gatggtacat
     1981 attggcaata acccgccgga tctggacgaa atagcggagc gtctgacggc gggcgatatc
     2041 attacccact gttacaacgg taagccgaac cgtattcttc ggcctgacgg cgagctgcgc
     2101 gcctcagtga cacgagcgct ggcgcgcggc gtgcgtctgg acgtcgggca tggtaccgcc
     2161 agcctgagct ttgcggtggc taaacgcgct attagcctgg ggattttacc gcataccatc
     2221 agttccgata tctactgccg taaccgcatc aacggcccgg tacattcgct ggctaatgtg
     2281 atgtcgaaat tcctcgccat cggcatgtcg ctgccgcagg tcattgcgtg cgtgacggcc
     2341 aatgccgccg atagcctgaa tctgaaaacc aaaggacgtc ttcagccagg tctggatgcc
     2401 gacctgaccc tctttacgct taaacgccag cccaccgtgt tggtagacgc ggaaaacgac
     2461 agcttacagg ctgaagaatt gctgacgccg cttgccgcga tacgcgcagg caagggctat
     2521 atgaccgaac aagggagcgc ggaacatgcc ttcgattttt gagaagtatc aattaaaaca
     2581 ggtgattaac gcctccggac gtatgacggc gctcggcgtc tccacaccgc gcccggaagt
     2641 gatagacgcg gcgatggccg gaatgaatca gtatttcgag atgaaagatc tggtgaataa
     2701 aaccggtgag tacattgcga aattgctgga agtggaaggg gcgacggtag tctcctgcgc
     2761 cagtgcgggc cttgcccagt cggttgccgc ggtactggtt caggacagcg actggctgct
     2821 ggaaaacctg cacgttacac cgattgaaaa taacgaaatc gtcctgccaa agggccacaa
     2881 cgtcaacttt ggcgcgccgg tgggaacgat ggtggcgctg ggcggcggca aactggtgga
     2941 agccggttac gccaacgaat gttccgccgc ccagttggcg gcggccatta cgccgcgcac
     3001 ggcggctatt ctctatatca aatctcacca ctgcgtacag aaaagtatgc tcagcgtgga
     3061 gcaggctgcg gtggtggcgc gcacgcataa tctgccgctg attgtggaca cggcggcgga
     3121 agaagatttg cagtgctact accgcgtggg cgcagatctc gttatctata gcggcgcaaa
     3181 agcgattgaa gggccgacca gcgggctggt gattggcaaa acacagtatg ttgagtgggt
     3241 aaaacgtcag tcagcgggca ttggccgggc gatgaaggtc ggcaaagagg gaattgttgg
     3301 cctgacctgc gccattgaat tgtacctgcg ggcgcaaaaa gagagcggcg cggagatggt
     3361 agaaaaaatg gcgcccttta tcgacacgtt gaacacgttt aacggcgtca gcgcccgcgt
     3421 ggtgtgggac agcgccggac gcgatatcgc gcgcacggaa attaagtttg atgaagccgt
     3481 taccggcatc gccacaggcg acctggtcga cgcgctgaag caaggggaat acgcgattta
     3541 ctttcgcgga tacaaagcca acgaagggat tattgaagcg gatgtccgca gcgtcgatcg
     3601 cgcgcagtta gcgattgtgg cgcgtcgtat tggcgaggtg attaatcagg agaaacaagc
     3661 atgaaactga cccctaactt ttaccgcgat cgcgtttgcc tgaacgtact ggccggttcg
     3721 aaagataacg cccgggaaat ctacgcggcg gcggaaggtc atgtgctggt tggcgtgctc
     3781 tccaaaaact atccggatgt ggcaagcgca gtcgcggata tgcgtgaata tgcggcgctt
     3841 atcgacaatg cgctctccgt cggattgggg gcaggcgatc ctaaccagtc ggcgatggtg
     3901 agcgaaatct cgcgtcaggt acagccgcag catgtcaacc aggtgtttac cggcgtaggg
     3961 ggcagccggg cgctgctggg gcaaaacgag acggtggtga acggtcttgt ctcgccgacc
     4021 ggcacgccgg ggctggtgaa aatttccacc ggcccgctaa gcagccgcgc gccggacggc
     4081 atcgtaccca tagaaacggc gattgcgcta ctcaaagaca tgggcggcag ctctgttaaa
     4141 tactttccga tgggaggact cacctgtcgc gacgagtata aagcggtggc tgacgcctgc
     4201 gcccgccatg atttctggct ggaaccgacg ggcggtatcg atctggaaaa cttcgccgag
     4261 attctgcaca tcgcccttga tgcaggtgta agcaaaatca ttcctcacat ttatagttcg
     4321 attattgata aggtgagcgg caacacccgt gcggacgatg tgcgtcagtt actcgctatc
     4381 gtccggtcgc gtgtcggcta atcatgagga gagagacgtg cgattcccca accaacgttt
     4441 agcgcagcta tttgcgatgc tgcaaaacga gacgctgccg caggacgagc tggcgcagcg
     4501 gttgtcggtc tccacgcgta ccgttcgggc ggatatcgcc gcgctgaaca tgttgctgac
     4561 gccgcatggc gcgcaattta ctctcagtcg cggcaacggg tatcaactca aaattgatga
     4621 tccggcacgt tatcaatccc tgcaaacgca gcaatctccc acgctggcgc gcggtccgcg
     4681 caccagccag gagcggatcc actatttgct ggcgcgtttt ttaacctccg ccttctcgct
     4741 gaagctggag gatttagcag atgaatggtt tgtcagccgt gcgacgttgc agaacgatat
     4801 ggcggacgtg cgcgagcatt tgctgcgtta tcatctgacg ctggaaacgc gtccgcgtca
     4861 tggcatgaaa ttgtttggcg gagagatggc gattcgcgcc tgtctgaccg accttttatg
     4921 gacgctggtg cagcaggagc cctcccatcc gttaattgtt agtaccacgc tgaacaccga
     4981 ggtgtctcaa cggctgcagt ctcttttgcc ggatattttc tctcattgtc aaatccgcct
     5041 gaccgatgag ggcgagctgt ttctgcgttt atactgcgcg gtggcggtac ggcgtattcg
     5101 cgaggggtat ccgttatcgg aatgcgtggc agaggaggtc gatgaaaagg tgcgccatgc
     5161 ggcgcatgag attgcggagc tactacaaca gctggctgac aagccgctgt cggagccgga
     5221 agtaagctgg ctgaaggtgc atattgccgc ccgccaggta caggagattg cccccagcgc
     5281 cattaatgcc gatgatgaag aggcgctggt gcactatatc ctcaatttta ttaataccca
     5341 gtacaactat aacctgttga atgataaaca gcttcacgcg gacttgctga cccacatcaa
     5401 aacgatgatc acccgcgtgc gctaccagat catgatcccc aacccactac tggaaaatat
     5461 taagcagcac tatccgatgg cgtgggatat gacgttggcg gcgatatcga gttggggaaa
     5521 atacacgccg tataccatta gcgaaaacga aatcggtttt ctggtgctgc atattggcgt
     5581 tgggctggaa cgtagttaca acattggcta ccagcggcag ccgcaggtac tgctggtgtg
     5641 cgatgctggt aatgcgatgg tgcggatgat tgaagcggta ctggcgcgga aatacccgca
     5701 gattgagatt gcccgcactc tgacgctacg cgactatgag gcgcgggaca gtatggtgga
     5761 ggattttgtg atttccacag cgcggatcgg cgaaaaagat aagccggtca tcatgatcgc
     5821 gccctttcct accgactatc aattggagca gatcggtaag ctggtgctgg tggacagaac
     5881 ccgtccgtgg atgctggata aatatttcga tgcctcgcat tttcgcatcg tggaggggga
     5941 aataaatcaa cagacgctgt ttaaaacgct gtgcgatcag ttgcacgagg aaggctttgt
     6001 tgatgcggcg tttctcgatt cggttattga acgtgaagct atcgtcagta cgttattagg
     6061 cgacgggatt gccttgccac acgcgctggg gctgctggcg aagaaaacgg tggtttatac
     6121 ggtgctcgcg ccgcagggga ttgcctgggg tgacgaaacg gcgcacgtta tttttttact
     6181 cgccatcagc aaaagtgaat atgaagaggc gatggccatc tacgatattt tcgtcacttt
     6241 cctgcgcgaa cgcgccatga cgcgcctctg cgcatgtcag aattttacgc aatttaaaac
     6301 ggtcgcaatg gagtgtgtga gtcgcttttg agaggcgtta tccagaattc gatgtaatgc
     6361 gaatgtaatg ctaaactgca ttacacattc gattctcctg gaggcataat ggccacgctg
     6421 aacgtccgtc tggatgacaa actcaaaaat gaggcttatg ccgtgctgga aaaactgaac
     6481 attactccaa cggaagccgt gcgattactg ttccagtacg tcgcggaaac ggggcgcatg
     6541 ccagtgaaaa ccgtcactct tagcgacagt gaagatgcac tgattcagac agttcgggag
     6601 aggctgtcta gtccgcaaaa gggaatcaag gttagtctgg atgacttatg aactggaatt
     6661 cgacccgagg gccttaaaag agtggcataa gctgggcgat acggtgaagg ctcagcttaa
     6721 gaaaaagttg gctgatgtgc tattgaaccc cagaatcgac tctgcccgtt taaacggtct
     6781 tcctgactgc tataaaatta agcttaaatc gtccggttat cgtctggtgt accaggttcg
     6841 ggatgacgtt gtgattgtgt ttgttgttgc ggtcggcaag cgagaacatt cagccgtcta
     6901 tcacgatgca aacaaacggc tttagcgatc aacgcaaatg atgcactact tggttgctgc
     6961 taccgcgcca gataagcgcc gggtctttca gatcctgcac aaatttgcca tcgaccagca
     7021 cgttgatgag attgaccacc tgcatctgtg cggcgttgag ttcatcgagc ctgtagccgg
     7081 tccacaccca gatatctttc cccgggcact ccgcgtggat gcgttgtacc agtgccagga
     7141 tatccggtac gttttgcgga tgcagcggat cgccgcccga cagcgagatc ccctgacggt
     7201 gaatgcgcgt gtcgttcaga tcggcaatga tcttatcttc catctctttg gtaaacggct
     7261 ggccggaatt gagccgccag gtgcttttgt tatagcagcc agggcattca tgcacgcacc
     7321 ctgacacaaa cagggtgcag cgggtaccgg ggccgttaac gatgtcgacg ggatagtatt
     7381 gatggtagcg catagcgggt gtccagaaag catgtaggcc ggataaggtg cttgcaccgc
     7441 atccggcaac attgtgatgc ctgatgacga cgcgattgcg tcttatcagg cctacggtct
     7501 ttgcaaacgg aaattaacct atctgcccgt tgcctaaatg cttcacgcgg cgcttcactt
     7561 cttcctgctt accggcgtta aacggacgcg cgtccgggct gcctaaataa ccgcacacgc
     7621 gacgggtaac cgagacgcgc gcggcgtcgt ggttgccgca tttcgggcag gtgaaacctt
     7681 tactggtaca ttcgaactcg ccggtaaagc cgcactcgta gcattcatcg atcggcgtgt
     7741 tggtgccgta atacggtaca tgctgatagc tgtaatccca gacatcttcc agcgctttca
     7801 ggttgtgctg aatgttcggg tattcgccgt agcaaatgaa acccccgttc gccagcggcg
     7861 gatacggcgc ttcgaaactg attttgtcgt acgggttgac cttcttctcc acgtcgaggt
     7921 ggaagctgtt ggtgtagtaa cctttatcgg ttacgcccgg caccacgccg aactcggcgg
     7981 tatccagacg gcagaagcgg tcacagaggt tttcacttgg cgtgctgtac agactaaagc
     8041 cgtagccggt ctcgtctttc cactgatcca cggcctggcg cagacgctcc acaatcgcga
     8101 tgcctttagc gcgaagttgc tcgctgtcgt acaggtgttc gccgccgaac agcgcgttaa
     8161 tggtttcatg gataccaatg tagcccagag agatggacgc acgaccattt ttaaagattt
     8221 cagacacgtc gtcgtccgct ttcagccgca cgccgcaggc gccttccata tacaggatag
     8281 gcgcgacacg ggctttcacg ccttcaaggc gggcgatacg ggtcatcagc gccttccgcg
     8341 ccagcgccag acgttcatcc agcagtttcc agaatgcggt ttcgtcgcct tttgcttcca
     8401 gcgcgatgcg cggcaggtta aggctaatca cgcccaagtt gttacgcccg tcgtggatct
     8461 gctcgccgtt ttcgttctcc cacacgccga ggaaactgcg gcagcccatt ggcgttttga
     8521 acgaaccggt gactttgacc acctgatcgt agttgagaat gtccggatac atgcgcttgc
     8581 tcgcgcactc cagcgccagt tgtttaatgt cgtagttcgg atcgccaaac ttgtggttca
     8641 aaccatcgcg gatagcgaag accagttttg ggaacacggc ggttttgcga tttttaccca
     8701 gaccggcgat acggttacgc aaaatagacg cctggatcag acgcgactcc caactggtgc
     8761 cgaggccaaa accaaaggtc acgaaaggcg tctggccgtt agcggtgtgc agcgtgttaa
     8821 cttcgtattc cagcgactgg aaggcgtcgt agcactcttt ttcggtgcga gaacgcgcat
     8881 acccttcggc atccgggatc tgccactcat cggcggtttt gcggtgcttg ttatagcttt
     8941 cggtgacaaa cggcgccagc acttcgtcga tacggttaat ggtggtgccg ccataaatat
     9001 ggctggcgac ctgcgcgata atctgcgcgg taacggcagt ggcggtagag atagattttg
     9061 gcggttcgat ctcggcgtta cccatcttaa agccctgggt caacatgcct ttcaggtcga
     9121 tcaacataca gttgaacatc gggaagaacg gcgaatagtc gagatcgtga tagtggatat
     9181 cgccgcgctc atgcgcttgt actacgtcac gcggcaacag gtgctggcgg gcatagtgtt
     9241 tggcgacaat cccggccagc aaatcgcgct gggtgggaat gactttactg tctttgttgg
     9301 cgttttcatt gagcaacgcg gagttagttt gctctaccag gccgcgaatt tcctggttca
     9361 gacgaccacg cttttcacgc tgaatgtcac gatcgtgacg gtattcgatg taggcgcggg
     9421 caagctgttt gtacgggccg gacatcagtt ggttttcaac cgcagtttgg atctcgttaa
     9481 tatccacctg actgcgtgcg ttcatttggc tgctaacgac ttctgcgacg gtggcacagt
     9541 aatctgcgtc atcgactccc gctgctttag ctgcacgtag aatggcttcc ttaatgcgct
     9601 ctgatttgaa tggcacttta cagccatctc gtttcatcac atgcggtgtc atgatcactc
     9661 catatttgta agaacaggtt atccacagag gccggggaag ccataacagg tttattcatc
     9721 tcttttccaa tgacttcccg caatcctgac ccaggttatc cacaattcac cttgtgtcga
     9781 gtgaacaggt gttgtagcaa ttgtagtcaa ttaatacaac atattgggtc ggcgtgcatt
     9841 ttaaagtcta tatgtagtga tttgcatcaa ggatgtttgc aattttattg atgtagaaca
     9901 aggtaaaaat cagagcgtac agatggcggg cgctgtagcg tttgtaaaag atagcaagaa
     9961 aaatctgatt aattattcaa caaaaacaga cagtaacctg gagcaacgcc acagcccgtg
    10021 tcaataggtt tgtggcgttt atccgtataa ggacgtcgcg ttagcgttgt aaccaccaga
    10081 tggcttcaaa tgggcggagc gtcatcgcgg ctggctggct ggcgacctcg ccataattat
    10141 gcagtagcgc ctgccactgt cctttgatat gcggtggatg ccactcctga cactggtcgc
    10201 tcagattggc gacaaccagc agggtttgcc cctgccactg gcgacgataa caccatactg
    10261 atgggctacc cgggaggaga tcctgataat cgccccagat cattacaggc tgggttttac
    10321 gtagcgcaat cagcttttga taggtgtaaa acaccgagtt ttcatcgcgt aatgccgccg
    10381 cgacattaac ctccgtatag ttatcgcaca ggcttatcca cggctcgccc tgggtgaaac
    10441 cggcgttttt accgttgtcc cactgcatcg gcgtgcggct gttgtcgcgg gatttactgg
    10501 ccaggatagc cagtagttcg tcggggtcgc gtccggcggc gcgtagcgcg gcaaacatgt
    10561 tatggctttc cacgtcgcga taatcggtga tgcgggtaaa gtgtgggttg gtcatgccga
    10621 tttcttcgcc ctgatagata taaggcgtcc cttgcatacc gtgcagcgcc atcgccagca
    10681 ttttcgcggc tggaacccgg tattcaccct cgtcgccaaa gcgggaaacg atgcgcggct
    10741 gatcgtgatt acaccagaat aacgcgttcc aggcgacgtt atgcatcccc tgttgccatt
    10801 ggcggaacaa cgctttcagc gccacataat caggttttgc cagcgtccac ttttcgccat
    10861 tggggtaatc caccttcaga tgatgaaaat tgaaggtcat cgagagttcg tcgccgctaa
    10921 gcgcggcata ttgctggcag ttttccagcg tggtagagga catttcgcct accgtcatca
    10981 gattacgcgg cgtaaaaacg tcacggttca tttcgcgtaa aaacgtatgc gtgcgcggtc
    11041 cgtcggtata aaagcggcgt ccgtcgcccg tcggatcgtc aggaaaatcc tgatctttgg
    11101 cgatcaggtt caccacgtcc agacgcaggc catccacgcc gcgatcggcc cagaattcgc
    11161 agaccttttt cagctcggcg cgcacggcgg ggttttccca gttcaggtcg gcctgttcag
    11221 gcgcgaaaag gtgtaaataa tattgttcgc tctggctatg ccagcgccag gcgctgccgc
    11281 caaatttgga ttgccagtta ttcgggcaga catccggcgt gccgtcgcgc cagatgtaaa
    11341 actgacggta tgggctctct ttgttcagcg cttcgcgaaa ccaggcgtgc tgggtagaag
    11401 tatggttaaa caccatatcc aggatgatgc gaatgccgcg tgctttcgcc tgcgcgacca
    11461 gctcgtcaaa atcatccagc gtgccgtagg tcgggtcgat agccgtataa tttgcgacgt
    11521 cataaccgtt atccacctgt ggcgagatat aaaacggcgt gagccagatg gcgtccacgc
    11581 cgagtcgctg tagatagtca aggcgctgcg tgacgccgcg taaatcgccg gtgccgctgc
    11641 cggtcgtgtc ctgaaaactt ttcgggtaga tctgataaat aacgccgttt tgccaccaga
    11701 ggggaatagt cattgtagtt tcctgcaagt acgttgggac gcaactgcgc cccgaagaag
    11761 aattagacaa tttgtaatgt gccctgacga tgcttacgct gatagataaa ggtggtcaga
    11821 atcaccggga taacgatcgc gataaccatc gccatcgcaa acacctgcca gtaagtcggc
    11881 tggatagaga gaatgcccgg caggccgcca acgccgatgc cgtttgccat tacgccattc
    11941 agaccacaga gcagaccggc aaggccagag ccgatcatcg cgcacagcat cgggaagcga
    12001 tatttgatgt tgatgctgta cattgccggt tcggccaccc ccagataggc ggagatcgcc
    12061 gccggaacgg aaatttcacg ttcattgtgt ttacggctgg agatgataat gcccaccacg
    12121 gcggaggctt gcgcgatatt cgacagcgca atcagcggcc agactggcgt accgcccatg
    12181 ctctgaacca tctgcatatc gatagcgagc gtggtctggt ggacgccggt aatgaccaac
    12241 ggggcataca ggaagccgaa cagcgccgcg cctatcgggg cgaaactgcc ggtcatcaga
    12301 taacgtaccg caaaggccac gccgtcgccg atcatgcgac caaaggggcc gataaaggcg
    12361 tgggcgagaa agacggccag tatcaacgaa cacaccggga cgacgaccag gtagagataa
    12421 tccggcacga tgcgtttcaa ccgcgtttca ataaatccaa gcgccagtcc tgccagtagc
    12481 gccgggataa cctgcgcctg gtagcctatt ttctcaatac taaatacgcc gaagttccag
    12541 acgtccggcg tttgctggcc cagcagatac gcattcatca actgcggcga caccagcgtc
    12601 acgccgagca cgataccaag aatcggcgtg ccgcccattt ttttcaccgc cgaccagcag
    12661 atccccaccg gcagatagaa aaagatcgct tcgccgatca accataaaaa atcataaagc
    12721 gtttttagcg ccggatgcat ctgcgccagt gtttgaccgt ggctcatcgg cacatcgccg
    12781 atcacgttac gaaagcctaa gatcaaaccg ccgctgatca atgccggtag tagcggaaag
    12841 aagatctccg cgaagtggga aattaactgc tcatgccact tcatgttctg gcgagcggct
    12901 ttttttgcct gctctttatc agcatacgct ttgccggtgg tctccagcag cgcgttatag
    12961 taatcgccga cttcggtgcc gatcaccacc tgaaactgcc cggcgttggt gaaacagcct
    13021 ttaaccatcg gcaattgttc gatctctttt ggtcgggcgt tcgcgggctg gtggagcaca
    13081 aagcgcaggc gagtaatgca gtggctcacc gtggcgatgt tgtcgcgccc gccaaccagg
    13141 tcaatcagcc ggtcgatatc ggcttgtttt actttgctca tcgtaaagcc tcatggcaga
    13201 ggaggtaagt tatgggttgg cgcaagagta gctcttcaac gttggtttaa aaatgggaac
    13261 gttcccgaaa cgcggcgacg atcacaaatt acgcatggta ttccgtttaa tcagccactc
    13321 aggcgagggt agaaggaatg acgatccggc gcggatcgca gcggccattg atctgttcga
    13381 tcagctgcaa agccgcctgc cgtccggctt cagcatagcc aggatcgaca gtgacgatct
    13441 ccggatgcag gaattttatc agcggcgtat tcccgatgct tgccagttgc agcgtctcaa
    13501 tacgttgctc ctgtaaatac ttactggcgc ccaacgccag cgtatcggtg gcgcagacta
    13561 acgcggtggt atccggcatg atgacacttg ccgtatgctc atagccctgc ttcatggcaa
    13621 gaccgggaag ggcggcgacg ggatgaagtt tatgtttttt gcaaaacgcc aggtatgcgt
    13681 catgccgacg tttgccggtg gtaatatcgc tatgaggaac gcccagaaag ctaatgttgc
    13741 ggtgtccctg ctcatacagc cgctgcataa ggatatgaat cgcgccctcg tcgtcgtaac
    13801 agacggaggc aaaaccttgc gcatctcttg ccagcagcac cagcgaggct ttccaggggg
    13861 cgatcaactc ttctgtgatg ccggtaaagc caaacagcac cacgccatca atgttacgtc
    13921 gcctgagcat gcccagatgt tccattacca gcatcggcga gaactgactt tccatcataa
    13981 tagggtcgta gccctgttca taaaacgcag gcagcatggt ctgaaccgcg aggttttcag
    14041 acaacgaatc aaggcgagtg acgataatag cgaccacttt atcgctttgt ccccgcatcg
    14101 cacgggcgga gcgggacgga gagaaaccgt gttgattcat caccgcttcg acacgctcgc
    14161 gggtacgttt gcttacgccg ctttcattgt taagcacgcg ggaaacggtt gatttcccta
    14221 cgccgctcag gcgggcaatg tctttgatag tgagccggtt ttgcatcctg ttttcccgtg
    14281 gcgtgacgct gatggtgata aaaagagtaa ctttactcaa gcgaagggca atgggcaaag
    14341 tctggtttat cgttggttta attacgtaac ggtatgatac cgccataatt gccacaaaac
    14401 ttatggattt atgcgtataa tccgcggcgc aaattattta cttaccggag gcgacatgga
    14461 ccctgaaccc acccctctcc cgcgatggag aattttcctt ttccggtaag cctgcctctg
    14521 ctgtcttacc ggtgtgtaag acagtgacac aataacgtcc ctgtttttat ttaaacattg
    14581 ctcatcgggc aaggctttgc cgcgcctgaa gaattttctg cgcctgactt cggcgcggag
    14641 ggattaccta tgctaaaaac cattacccgc cagctttttg cccggcttaa tcgtcatttg
    14701 ccttatcgtc tggttcaccg cgatccgctg cccggcgcgc agaccgcggt aaacgcgact
    14761 atcccgcctt cgctgagcga gcgctgtctg aaaatcgcgg caatggagca ggagacgctc
    14821 tggcgcgttt ttgatacgca cccggaggga ttaaacgccg ccgaggtgac gcgtgcgcgt
    14881 gaaaagcatg gcgaaaaccg ccttccggca cagaaaccct cgccgtggtg ggtgcatctg
    14941 tgggtatgtt atcgcaatcc tttcaacatt ttactcacga ttcttggcgg catttcttat
    15001 gccacggagg atctgtttgc cgcaggcgtt atcgccctga tggtcggtat ctcaacgctg
    15061 ctgaattttg tgcaggaagc gcgctcgacg aaagcggcgg acgcgctaaa agcgatggtg
    15121 agcaataccg ctaccgtact gcgggttatt aatgaaaatg gcgaaaacgc ctggctggaa
    15181 ttacccatcg atcaactggt gcccggcgat attattaagc tggcggcggg ggatatgatc
    15241 ccggcggatt tacggattat ccaggcgcgc gatctgtttg tcgcccaggc gtcgctgacc
    15301 ggcgaatctc tgccggtcga gaaagtcgcc acgacgcgtg agccccggca aaataacccg
    15361 cttgagtgcg acacgctgtg ctttatgggg acgaacgtcg tgagcggaac ggcgcaggcc
    15421 gtggtgatgg cgaccggcgc cgacacctgg tttggtcaat tggcggggcg cgtgtcggaa
    15481 caagataacg agcagaacgc tttccagaaa ggaattagcc gcgtcagtat gttgctgatc
    15541 cgctttatgc tggtcatggc gccggtagta ctgattatta atggttacac gaaaggtgac
    15601 tggtgggaag cggcgctatt tgcgctctcg gtcgcggtag gactcacccc ggaaatgttg
    15661 ccgatgatcg tcacctctac cctcgcgcgc ggggcggtga agctctcgaa acagaaagtt
    15721 atcgtgaagc accttgatgc gattcagaac ttcggcgcga tggatattct gtgcaccgat
    15781 aaaaccggca cattgacgca ggacaaaatt atgctggaaa atcatacaga tatttccggt
    15841 aagcccagcg agcatgtact gcattgcgcc tggctgaaca gccattatca gaccggtcta
    15901 aaaaatttac tggatacggc ggtcctggag ggagtagacg aaaccgccgc gcgtcagctc
    15961 tccggacgct ggcagaaaat cgatgagatt ccgtttgatt ttgagcgtcg ccggatgtcg
    16021 gtggtggtcg ccgaagattc gaatgtgcat caactggtct gcaaaggcgc gctacaggag
    16081 atcctgaacg tgtgtactca ggtgcgccac aacggcgata ttgtgccgct ggacgacaat
    16141 atgctgcgcc gggtgaaacg cgttaccgac acgctgaacc gtcaggggct acgcgtggtc
    16201 gccgtcgcga ccaaatacct gcctgcgcgt gagggcgatt accaacgtat cgatgagtct
    16261 gacctcattc tggaagggta tatcgctttt ctcgatccgc cgaaagagac caccgcgccg
    16321 gcgttgaaag cgctgaaggc gagcggaatt acggtgaaaa ttctcaccgg cgacagcgag
    16381 ctggtagcgg cgaaagtttg ccatgaggtt gggctggatg cgggcgatgt cgttattggc
    16441 agtgatattg aaggattaag cgacgacgcg ctggcggcgc tggccgcccg tacgacgttg
    16501 tttgcgcgtc tgacgccgat gcataaagag cgcatcgtca ctttgctcaa acgcgagggg
    16561 catgtggtcg gttttatggg cgacgggatt aacgatgccc cggcgttgcg ggcagcggat
    16621 attggtatct cggtagatgg cgcggtggac atcgcccgtg aggcggccga tattatcctg
    16681 ctggaaaaga gcctgatggt gctggaagaa ggcgtcattg aaggtcgtcg tactttttct
    16741 aatatgttga aatatatcaa gatgacggcc agctcaaatt tcggtaacgt gtttagcgtg
    16801 ctggtagcga gcgctttttt gccgttcctg ccaatgctgc cgctgcactt gctgattcaa
    16861 aacctgctgt acgatgtatc ccaggtggcg attccgtttg ataatgtcga tgaagaacaa
    16921 attcaaaagc cgcagcgctg gaatccggcg gatttggggc gctttatggt ctttttcggt
    16981 ccgatcagct cgattttcga cattttgacc ttttgtctga tgtggtgggt atttcatgcg
    17041 aatacgccag aaacgcaaac cttgttccag tccggctggt ttgtggtggg attactatcg
    17101 caaacgctga ttgtgcatat gatccgtacc cgtcgtctgc cgtttattca aagtcgcgcc
    17161 gcctggccgc tgatggcgat gacgttgttg gtgatggtcg tgggagtttc gttgccgttt
    17221 tcgccgctgg cgtcttacct gcagttgcag gcgctgccgt taagctattt cccgtggctg
    17281 attgctattc tggcgggcta tatgacgtta acccagttag tgaaagggtt ttacagccga
    17341 cgttatggct ggcagtaaac actttcgtcg gggattcgcc agcgtgctta atccccgata
    17401 tcgctaacca aaccagatgc ccgtaaagct cgacaagttt aacgcgatcg gctttatctt
    17461 taaatttcag ggcttattca agcaactgta gaatgctata tgcaggcata aaaaagagga
    17521 atgtccagct aagtttgtaa aatacattct ctgcccccga gccagaacga gaggaggaga
    17581 tgtcccaccg ctggatatgt tttgcggata tgcgacgaaa gcggcgaata tagctaatgc
    17641 aataaactaa gtaaggagga atcgctaagg cggcagtggg tttaggaaac ataagggtaa
    17701 gcaatatggc tgcgataatg aagcataaaa agacgatctt cgcagtagat tctatctgtt
    17761 ttaattcctg gcgtatgctt tcagcatgtt tctcctgcca gcgacggagc gtgctgttgc
    17821 taaatccata ttcttcgcat aacgccttat tcggcacgcc gtttttagac tgttgcagaa
    17881 aatcggcgat ttgctcctcg gtaaaacgcg ctcttaccat tgccgcctct ccatggctgt
    17941 tggtgccccg aaccgggcaa acttgcgccg cccggcgggg atgacgtccg gcgcttagcg
    18001 acgaacagcg atcgcttcaa tctcaatttt cacgtctttc ggcagacggg caacttccac
    18061 gcaggaacgc gccgggaagg tcgcgttgtg ctcggtgaag aacgcttcgt aggtggcgtt
    18121 gacggtcgcg aaatcgttca ggtctttcac gaagacggtc gttttcacaa tgtcgcctac
    18181 tttcaggcca gcggcttcca cgatagcttt aacgttttcc agcgactgac gtgcctgagc
    18241 ggatacgtct tccgctacgg cgccggtttt cggatcgacc ggaatctgac cggaagtgat
    18301 taccatgcta cccaggtcta cgccctgtac gtaagggccg attgctgctg gtgcattttc
    18361 cgtcgcaata gttttgctca tgatttctcc tgaattacag cggtaataga atgtccccgc
    18421 tcattatagg gagccgggat ctcataacca acccccatta gttggccagc accacattat
    18481 gcgaaaactc tttttcacag tatttgcatt tgagggcgat atcattggcg cgttttttca
    18541 ctgcaaagct ggaggatacc ggttccgcgt ggctgatgca gttgctgttc gggcaaacca
    18601 gcacattatt aatacgctct ggcaggctgg ggcgcgattt cccgaccacg tcgtagttgt
    18661 cgatgcggtt aacggtggcc tgcggcgcgt acagagcaag ttggttaacc tgctcatcgg
    18721 tgaggaaggt gttttctatt ttgattaagt ctttacgccc catctcgcca gacgggagat
    18781 tcagaccgat agtgattcgc tgatcggtct cggtcaattt aaacagactc agcagtttaa
    18841 agcctacctg cgcagggata tggtcaatca cggtgccgca tttaatggct tcaacctgca
    18901 gtttgttatc gtgtgtcatc gcttttctcc cttacagact cagttcgcta ttcagtacca
    18961 acgccagtaa cgcctggcga gcgaaaatac cgttgcccgc ctgttggaag taccaggcgt
    19021 gtggcgtttt atccacatcc gtggtgattt catcaatcct cggcagcggg tgcagcactt
    19081 tcatattttc acgcgcgccg ttcaggtcgc tggcgcgcag aacaaactgc gccttcacat
    19141 tggcgtactc cgacgggtcg agacgctctt tctgtacgcg agtcatatag aggatgtcga
    19201 cgtcggccat gacctcttca atagaaccat gcaggctcca ggccatccct ttttcatcca
    19261 gcatatccag aatgtactgc ggcatcgcca gcgcgtccgg cgcgataaaa taaaaacggt
    19321 tgccgctaaa tttcgccagc gcctgggtta gcgaatgcac ggtgcggcca tatttcagat
    19381 cgccgaccat cgcgatatgc aggttatcca gacggccctg cgtttcctgg atggtgaaca
    19441 gatccaacag agtttgcgtc ggatgctgat tcgaaccgtc gcccgcattg agcaccggca
    19501 cctgaccgga aaactccgtc gccagacgtg ccgcgccttc ttgcggatgg cgcatcacaa
    19561 tcgcgtccac gtaagtgcta atcactgaga tcgtgtcggc taacgtttct ccttttttcc
    19621 ccagcgacgt gttggcgctg tcggagaagc ccactacgct ggcgcccagg cgatgcattg
    19681 aggtttcaaa cgacaggcgg gtacgcgtgg aggcttcgaa aaagcagctg gcgatcactt
    19741 tatgtttcaa aagctccggc tgcgggttgg cttttaattt cgccgccgtc gccagtacca
    19801 gattaagatc gtcgcggctg aggtcgttta tggaaatgat atgtttttga tatagcgggt
    19861 tagccatgtt tatctcctga cgcctgggca aaaaaaagcc cctcaattga ggggcttggt
    19921 attggttttc aacggaaaga aaaacggcag gcctgcgtct tttttcagac gcggtaagac
    19981 agaatgtcgt acacactgaa ccatgcttcc tcccggcaaa ttgtccgcga ttatactcag
    20041 ctctgttttg ggatcaagcg aattaatgca tgatttactt gtcgcaaacg gttcttatga
    20101 atttaaattc attttaagca aataattaat ttgtttgtgt accagcgccg tgcgctgaac
    20161 gacctgtggt gcgacccaga caatactgct accggcaacg acgccgagaa tttccggcaa
    20221 tgcgtggtaa tccagaattc tcgcgacggc gcgaccataa cctgccgccg tatggataag
    20281 gataaattcg ctattatgtt caacgctgac gaccatttcg gctattgaac gtccggcatc
    20341 cggcgaagga cgctgctggg gatttacgga ataaatcttt tgtcctttcg catttctgat
    20401 ttttattgcg cccagcagct tgagcaggcg cgaaaccgta gactgactga taccttcaaa
    20461 tccctcattt tgtaaatcgc ggcgaatctc ctcctgggac aggtaacttt atttcactaa
    20521 tcaggcgctg acaaaccgcc agttgctgtt gttctttggc ggagtaatca tcgtattcct
    20581 tcataaatgc accttatctt tattattgat atcaacggac tggcgaaatt tatcacattt
    20641 gtcacattga ttgcggatca atcgggcggt tttgcaggaa aatgagaagc tgatcaaaaa
    20701 aggtgacggc gtgcctgatg gcgctgtgct tatcagtcct gtcggataag acgcgtcgcc
    20761 atctggctcg ttacatcatc gctccgatgc tcagtaccgc catattcagc aatgtcagga
    20821 tcagcaacag cggcgcgacc catttcagat agcgaacata gggaacccgc gcgatcgcca
    20881 gaccgcccat gaccacggcg gaggtgggcg taaccaggtt cacaatcccg gaggccgact
    20941 ggtaggcggt tacgaccaaa tcccgctgta cgtgggcaaa atccgctaac ggcgccataa
    21001 tgggcatcgt caatacggca agaccggaag aggagggcac caggaaggag agcaatactt
    21061 ccagccagta ggttacgttt atgaaaatgg tggtagagag gccggaaacc agactttccg
    21121 cgctgtgcaa aatggtgtgg gtaatcatac cgttatccat gaccaccaca atgccgcgcg
    21181 cgataccaat aattagcgcc acgccgagca aatcccgcgc gccgtcgata aaggtactgg
    21241 tgaacgcttc ctcgcccatc cgcgttatca cgccaacgat aatcgccgcc gccagaaaga
    21301 cgccggagat ttccgccatc caccagccga gaaccgccac gccgtaaatc atcaccgcga
    21361 aagaggcggc gaagatcagc agcacccatt tccgggtagc cgtaaactcc agcagtgtat
    21421 tggcgcgatt gccgaggaaa tgggcgcggt tttccgccat tttatccgcc acgatagaaa
    21481 gctcaggatg ggcgcggact ttgcgcgcat agcgcattac ccaaaacacg cacagtacgt
    21541 agccgacaat taacagcagt acacgcatca gcatgccctg cgtaaaaggg atgccggcgg
    21601 cgttggcggc aatgaccgtg gcgaaaggat taatggtcga accgagcgtg cctatccccg
    21661 cgccgagcag tacggttgcc gtcgccacta acggatcgaa gcgggccgcc atcatgaccg
    21721 gcaccagcag cgtgtagaag ggcaacgact cctccgccat gccatagata gtgccgcctg
    21781 cggcgaacag cgccatcaga atggggatca tccactcatc tttgccgttg agtttgatag
    21841 ttacccgttc aataccggca tcaatcgccc ccgttttatt caccaccccc agaaagccgc
    21901 cgataatcaa gacaaacagc gcgacgtcaa tggcgccggc ggtgtaggtt tcgtggttat
    21961 agaggccgtc aatcggcgcc agtaaaacag cggtaatccc ttgcggatgc gcgtccacgg
    22021 gggcatacgt tcccgccacc ggcacctctt ttcccagcgt ggcgttcatc gccatttggt
    22081 attttcccgc cggcacaatc caggtcatca ccgcgaccag ggcaataaga ataaacagga
    22141 tggtataagc ggtgggaaat ttaaatttac ccatgatgtt ctctcctgat atcacggata
    22201 tgcgccgcga gggcgcatat cctgtgggat tagtcgccga gcgtcgccac catgaccgct
    22261 ttgatggtgt gcatccggtt ttccgcttca tcgaagacca tcgagcctgc ggactcgaac
    22321 acctcttccg tgacctccag tcctttcagg ccgtaagcca tttcgatttc gcgtcccact
    22381 ttggtgtgct cgttatggaa ggcgggcagg cagtgcataa acttcacatc aggattaccg
    22441 gtagcgttta ccacctgctg gttgacctga tatggcgtca tcagactgac gcgctccgcc
    22501 caggcttctt tgggttctcc catcgagacc cagacgtcgg tatagaggaa atccacaccg
    22561 tgaacgccat cttcaacgct ctccgttaag gtgatacgag cgccggtaac gctggcgatt
    22621 tcccggcact gcgcgaccag cgcggcatca ggccagaagg actttggcgc tatcagacgg
    22681 atatccatgc ccatcttcgc cgcgcccacc atcagcgaat tgcccatgtt gttgcgcgcg
    22741 tcgcccaggt aggcgaagct cagttccggc agcgttttgc ccggcgcatg ttccagcatg
    22801 gtcatcagat cggccaggat ctgtgtgggg tgaaattcat cggtcaggcc gttccagacg
    22861 ggaacgcccg cgtattcccc cagctcttcc acaatgtgtt gaccaaatcc gcgatattcg
    22921 atgccgtcat acatccgccc caggacgcga gcagtatctt tcatggactc tttatggccg
    22981 atctgcgagc cgcttgggcc gagataagtc acctgcgcgc cctggtcgaa cgcggcgact
    23041 tcaaacgcgc atcgggtgcg agtagaggtt ttttcaaaaa tcagcgcgat gtttttgccg
    23101 atcagtgttt gcttttcgca tccggctttt tttgcggctt tcagctcaat agccagatcg
    23161 atgaggtgtt ggatttccgc cggggtgtag tcaagcagct tcaaaaagtt acgatttttc
    23221 agtgaaataa ccattacaat atccttgtta aaatgaattg cctgatggcg ctgcgcttat
    23281 ccggcccacg gttatgcgcg ctctgtaggc cggataaggc ggaagccgcc atccggtaaa
    23341 aagccttatg cgtcaacgtc ggcggtttca caccgaatca aagtaccttt ctcgcccgcg
    23401 agaatggctt gcccatccgc cagcgagccg attccggcaa tgccgcagca atggctgaca
    23461 aactcagcgc aggcggtcac tttcgggccc atcgaaccgg cgtcgaactg catttcacga
    23521 agcagctccg gcgtaacctg cgccagcggg cgttgggtgg gtttgcccca gtcgagatac
    23581 accgcgtcga catcggtcag aatgagcagc gcgtcggcgt gaatttggct ggcaagcagg
    23641 gcggcggaca gatctttgtc gatcaccgcc tcgataccgt ggtagccatc ggctttttcc
    23701 acgaccggca caccgccgcc gccgttacag ataaccaggt gatcgcggct aatcagcgcg
    23761 cggatggcat cgttttccac aatgcgtttc ggctgcgagg agggcacaac gcggcggaag
    23821 gcgttaccgt cggctttgaa tacccagccc ttttctgcct gtaacgcacg ggcctgcgct
    23881 tcgtcgtaaa tggggccgat atatttggtt ggattgagga atgccgggtc gttggcatcg
    23941 acttcgacct gggtgagcag gacgctgatt tcacgctccg gcagatgatt cttcagcgcc
    24001 tgttgcagca tgtagccaat catgccctgg ctttccgcac cgagaatatc gagcgggtag
    24061 ggcgtaacgt tagcgtaggc gctattttgt agcgccagca gccctatctg tgggccgttg
    24121 ccatgcacta acactacgcg ccattgccgg gtaagctggg cgatggttct ggccgccagt
    24181 tcgatatttt tacgctgaat atcagcctcc agcggttcgc cgcgtttgag cagcgcattg
    24241 ccgcccagcg cgacgaccag tgtgcgtttg ttttccataa cgtctccttt aaataccatc
    24301 gcgttccagt ggacagctca tgcagcgtgc gcctccgcgc ccgcgaccca gttcatcgcc
    24361 gggaatggga aggacggtaa tgccggcttt gtcgtatttt tcgttggtcc agatgttgcg
    24421 ctcatagccc accaccacgc cgggacgcag ggtgagcacg ttattggcgt cattccactg
    24481 ttcgcgctca gcttcaaatg cgtcgccgcc agtggtgatt aagcgcacct gatcgatgcc
    24541 aagcgctgtt tcaagagcat gaaccagcgt gctctcctgg gttcgtttca gaccgccgcg
    24601 tccgtctggc gtcagcgtcc agcactgaac gtccgggcga acgacttccg gatagacaga
    24661 gaaggtgtcg atatcaatgt gggtcatgac ggtgtcaagg tgcatgcagg agcgatgttt
    24721 tggcagttca acggcaatga cgcgttccgc ctgacgatgt ttaaacaatg cctgcgccag
    24781 gaactcgaca ccctgcggcg tagtacgttc agacataccg atcaacaccg cgccgcggcc
    24841 aatcaccagc acatcgccgc cctctaaagt ggcgtggtcg taattaatgt tctcgtcgcc
    24901 gaaatattta atgaaatcac cgtctgcgaa ttgtggatgc cagcgataaa tagcacgtaa
    24961 attattcgtt tcacgttggc gtgcaggttt cgccatgggg ttaattgaga cgccgttata
    25021 tatccagcag gacgtgtcac gggtaaatag gtgattcggt aatggcttca taataaagtc
    25081 attaatatcg tgagtatcga ccaccatatt ttttatggag gcggggattt cgccgtaagt
    25141 taaaccgccg cttaaatggc gagccagttc acggtgcggc atatccgcca gccaggcgcg
    25201 aatatctgcg gcaaaggtgg gcccaaggcg ataatcggaa atttgcgtat ccagtagcca
    25261 ggctttagcg tcagccacat ccagtgtttg ggtgagcagg tcggttaaca gcaacacttc
    25321 tatcccttgc tggcgcagcg tgttggcaaa aatgtcatgc tcttcgccag cgcgctctac
    25381 ggataataca tcgtcaaaaa gtaattcctg acaatttgaa ggggtaagtc tttttaggct
    25441 gagattggga cgatgcaaca ttacgctgcg taattgaccg atttcagaac cgacaaaatg
    25501 cttttccatc attatacctt ttacataatt tcaagaataa agaaggagtg gctgcaaata
    25561 tttagcgtgc ttgcagtcgc ggcgtttcag ttaaattcgg gagcaatgat tgaattttat
    25621 ttgggttgtt aatgtgatga gattcacatc aattaaggag tgctattttt cttacttaat
    25681 atatgagccg ggtcagagaa attcaaaaaa caataag
//
LOCUS       DAJVBX010000042        25507 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.042, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000042 DAJVBX010000000
VERSION     DAJVBX010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 25507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25507
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.042"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..2538
                     /gene="sadA"
                     /locus_tag="OPV72_001531"
     CDS             <1..2538
                     /gene="sadA"
                     /locus_tag="OPV72_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric autotransporter adhesin SadA"
                     /protein_id="HCR9913877.1"
                     /translation="DALLWDADSGTFSASRNGSASKITNLAAGTLAADSTDAVNGSQL
                     YETNQKVDQNTSAIADINTSITNLSSDNLSWNETTNSFSASHGSSTTNKITNVAAGEL
                     SEESTDAVNGSQLFETNEKVDQNTTDIAANTTNITQNSTAIENLNTSVSDINTSITGL
                     TDNALLWDEDTGAFSANHGGSTSKITNVAAGALSEDSTDAVNGSQLYETNQKVDQNTS
                     AIADINTSITNLGTDALSWDDEEGAFSASHGTSGTNKITNVAAGEIASDSTDAINGSQ
                     LYETNMLISQYNESISQLAGDTSETYITENGTGVKYIRTNDNGLEGQDAYATGNGATA
                     VGYDAVASGAGCLALGQNSSSSIEGSIALGSGSTSNRAITTGIRETSATSDGVVIGYN
                     TTDRELLGALSLGTDGESYRQITNVADGSEAQDAVTVRQLQNAIGAVTTTPTKYYHAN
                     STEEDSLAVGTDSLAMGAKTIVNADAGIGIGLNTLVMADAINGIAIGSNARANHANSI
                     AMGNGSQTTRGAQTDYTAYNMDTPQNSVGEFSVGSEDGQRQITNVAAGSADTDAVNVG
                     QLKVTDAQVSRNTQSITNLNTQVSNLDTRVTNIENGIGDIVTTGSTKYFKTNTDGADA
                     NAQGADSVAIGSGSIAAAENSVALGTNSVADEANTVSVGSSTQQRRITNVAAGVNNTD
                     AVNVAQLKASEAGSVRYETNADGSVNYSVLNLGDGSGGTTRIGNVSAAVNDTDAVNYA
                     QLKRSVEEANTYTDQKMGEMNSKIKGIENKMSGGIASAMAMAGLPQAYAPGANMTSIA
                     GGTFNGESAVAIGVSMVSESGGWVYKLQGTSNSQGDYSAAIGAGFQW"
     gene            2837..4492
                     /gene="lldP"
                     /locus_tag="OPV72_001532"
     CDS             2837..4492
                     /gene="lldP"
                     /locus_tag="OPV72_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate permease"
                     /protein_id="HCR9913878.1"
                     /translation="MNLWQQNYDPAGNIWLSSLIASLPILFFFFALIKLKLKGYVAAS
                     WTVVIALAVALLFYKMPVDHALASVVYGFFYGLWPIAWIIIAAVFVYKISVKTGQFDI
                     IRSSILSITPDQRLQMLIVGFCFGAFLEGAAGFGAPVAITAALLVGLGFNPLYAAGLC
                     LIVNTAPVAFGAMGIPILVAGQVTDLDSFEIGQMVGRQLPFLTIIVLFWIMAIMDGWR
                     GVKETWPAVMVAGGSFAIAQYLSSNFIGPELPDIISSLVSLVCLTLFLKRWQPVRIFR
                     FGDMGASQVDQTLARTRYTTGQIVRAWSPFLFLTATVTLWSIPPFKALFAPGGALYDW
                     VINVPVPYLDKLVARMPPVVHEATAYAAVYKFDWFSATGTAILFAALLSIVWLKMKPS
                     AAIQTFGSTLKELALPIYSIGMVLAFAFISNYSGLSSTLALALAHTGSAFTFFSPFLG
                     WLGVFLTGSDTSSNALFASLQATAAQQIGVSDVLMVAANTTGGVTGKMISPQSIAIAC
                     AAVGLVGKESDLFRFTVKHSLIFTCMVGVITTLQAYVLTWMIP"
     gene            4489..5265
                     /gene="lldR"
                     /locus_tag="OPV72_001533"
     CDS             4489..5265
                     /gene="lldR"
                     /locus_tag="OPV72_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LldR"
                     /protein_id="HCR9913879.1"
                     /translation="MIVMPKRLSDEIASRVRALIEEQNLEAGMKLPAERQLALQLGVS
                     RNSLREALAKLVSEGVLVSRRGGGTFVRWQHETWSEQNIVQPLKMLMANDPDYSFDIL
                     EARHAIEASTAWHAAMRATAADKEKIRLCFDATLSEDPDLASQADVRFHLAIAEASHN
                     VVLLQTMRGFFDVLQSSVKQSRQRMYLVPPVFSKLTEQHQAVLDAILDGNAEGARKAM
                     MAHLSFVHTTIKRFDEDQARQARITRLPGDHNEMTRENKS"
     gene            5262..6452
                     /gene="lldD"
                     /locus_tag="OPV72_001534"
     CDS             5262..6452
                     /gene="lldD"
                     /locus_tag="OPV72_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent L-lactate dehydrogenase LldD"
                     /protein_id="HCR9913880.1"
                     /translation="MIISATSDYRAAAQRTLPPFLFHYIDGGAYAEYTLRRNVEDLSQ
                     VALRQRVLKNMSDLSLETTLFNETLSMPVALAPVGLCGMYARRGEVQAAAAADAKGIP
                     FTLSTVSVCPIEEVAPTLKRPMWFQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPT
                     PGARYRDAHSGMSGPNAAMRRYWQAVMHPKWAWDVGLNGRPHDLGNISAYLGKPTGLE
                     DYIGWLANNFDPSISWKDLEWIREFWDGPMVIKGILDPEDARDAVRFGADGIVVSNHG
                     GRQLDGVLSSARALPAIADAVKGDIAILADSGIRNGLDVVRMIALGADTVLLGRAYLY
                     ALATAGKTGVANLLDLIEKEMKVAMTLTGAKSISEISGDSLVQELGKSLPAALAPMSK
                     GDAA"
     gene            6517..6990
                     /gene="trmL"
                     /locus_tag="OPV72_001535"
     CDS             6517..6990
                     /gene="trmL"
                     /locus_tag="OPV72_001535"
                     /EC_number="2.1.1.-"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HCR9913881.1"
                     /translation="MLNIVLFEPEIPPNTGNIIRLCANTGFRLHIIEPMGFAWDDKRL
                     RRAGLDYHEFAAVQRHHDYAAFVAAENPQRLFALTTKGTPAHSAVSYQDGDYLMFGPE
                     TRGLPASILDALPKEQKIRIPMMPDSRSMNLSNAVSVVVYEAWRQLGYPGAVLRS"
     gene            complement(7058..8062)
                     /locus_tag="OPV72_001536"
     CDS             complement(7058..8062)
                     /locus_tag="OPV72_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCR9913882.1"
                     /translation="MKRTKSPRAPTLEDVARSAGLSPMTVSRALNSPQLVRPKTVEKV
                     MQAVRVTGYIPNALAGGLASRRSKLIAVVVPQINNNMFVDTIQSLSDELARRGYHILL
                     CVAGYTEQTEAELVATLLSRRPDGVVLTGIHHTIELKKVILNAAIPVVEIWDLTPTPL
                     DMLVGFSHEKVGQATGEYLLSKGYRRPGLLWTADRRAAQRKQGLCSVLQRHAIHAVPQ
                     VDVPLPASLSLGRSGLSQLFDEGTFDVIVCSSDTLAQGAMMEAESRGLRIPHDLAVIG
                     FGDLDFAASNRPSITTVSVDRRAIGQRAATLLADRIEQKPCAEAIVDIGFHLIERESA
                     "
     gene            8381..9577
                     /locus_tag="OPV72_001537"
     CDS             8381..9577
                     /locus_tag="OPV72_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-talarate/galactarate dehydratase"
                     /protein_id="HCR9913883.1"
                     /translation="MALSANSDAVTYAKAANTRTAAETGDRIEWVKLSLAFLPLATPV
                     SDAKVLTGRQKPLTEVAIIIAEIRSRDGFEGVGFSYSKRAGGQSIYAHAKEIADNLLG
                     EDPNDIDKIYTKLLWAGASVGRSGMAVQAISPIDIALWDMKAKRAGLPLAKLLGAHRD
                     SVQCYNTSGGFLHTPLDQVLKNVVISRENGIGGIKLKVGQPNCAEDIRRLTAVREALG
                     DEFPLMVDANQQWDRETAIRMGRKMEQFNLIWIEEPLDAYDIEGHAQLAAALDTPIAT
                     GEMLTSFREHEQLILGNASDFVQPDAPRVGGISPFLKIMDLAAKHGRKLAPHFAMEVH
                     LHLSAAYPLEPWLEHFEWLNPLFNEQLELRDGRMWISDRHGLGFTLSEQARRWTQLTC
                     EFGKRP"
     gene            9651..10961
                     /locus_tag="OPV72_001538"
                     /pseudo
     CDS             9651..10961
                     /locus_tag="OPV72_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462598.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(11044..11865)
                     /gene="cysE"
                     /locus_tag="OPV72_001539"
     CDS             complement(11044..11865)
                     /gene="cysE"
                     /locus_tag="OPV72_001539"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HCR9913884.1"
                     /translation="MPCEELEIVWKNIKAEARALADCEPMLASFYHATLLKHENLGSA
                     LSYMLANKLASPIMPAIAIREVVEEAYAADPEMIASAACDIQAVRTRDPAVDKYSTPL
                     LYLKGFHALQAYRIGHWLWNKGRRALAIFLQNQVSVSFQVDIHPAAKIGRGIMLDHAT
                     GIVVGETAVIEDDVSILQSVTLGGTGKTSGDRHPKIREGVMIGAGAKILGNIEVGRGA
                     KIGAGSVVLQPVPPHTTAAGVPARIVGKPGSDKPSMDMDQHFNGLHHTFEYGDGI"
     gene            complement(11943..12962)
                     /gene="gpsA"
                     /locus_tag="OPV72_001540"
     CDS             complement(11943..12962)
                     /gene="gpsA"
                     /locus_tag="OPV72_001540"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HCR9913885.1"
                     /translation="MNQSNASMTVIGAGSYGTALAITLARNGHQVVLWGHDPKHIATL
                     EHDRCNVAFLPDVPFPDTLHLESDLATALAASRNILVVVPSHVFSDVLRQIKPLMRPD
                     ARLVWATKGLEAETGRLLQDVAREALGDQIPLAVISGPTFAKELAAGLPTAISLASTD
                     ETFADDLQQLLHCGKSFRVYINADFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTAL
                     ITRGLTEMSRLGAALGADPATFMGMAGLGDLVLTCTDNQSRNRRFGMMLGQGMDVKGA
                     QDKIGQVVEGYRNTKEVRELAHRFGVEMPITEEIYQVLYCGKNAREAALTLLGRARKE
                     ELSRH"
     gene            complement(12962..13429)
                     /gene="secB"
                     /locus_tag="OPV72_001541"
     CDS             complement(12962..13429)
                     /gene="secB"
                     /locus_tag="OPV72_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015369180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HCR9913886.1"
                     /translation="MSEQNNTEMAFQIQRIYTKDVSFEAPNAPHVFQKDWQPEVKLDL
                     DTASSQLADDVYEVVLRVTVTASLGEETAFLCEVQQAGIFSISGIEGTQMAHCLGAYC
                     PNILFPYARECITSLVSRGTFPQLNLAPVNFDALFMNYLQQQAGEGTEEHQDA"
     gene            complement(13473..13724)
                     /gene="grxC"
                     /locus_tag="OPV72_001542"
     CDS             complement(13473..13724)
                     /gene="grxC"
                     /locus_tag="OPV72_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin 3"
                     /protein_id="HCR9913887.1"
                     /translation="MANIEIYTKATCPFCHRAKALLNSKGVSFQEIAIDGDAVKREEM
                     IKRSGRTTVPQIFIDAQHIGGCDDLYALDARGGLDPLLR"
     gene            complement(13810..14241)
                     /locus_tag="OPV72_001543"
     CDS             complement(13810..14241)
                     /locus_tag="OPV72_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HCR9913888.1"
                     /translation="MQEIMQFVGRHPILSIAWIALLVAVLFTTFKGLTSKVKVITRGE
                     ATRLINKEDAVVVDLRQRDDFRKGHIAGATNLLPSEIKANNVGELEKHKDKPIIVVDG
                     SGMQCQESANALTKAGFEKVFVLKEGVAGWSGENLPLVRGK"
     gene            14489..16033
                     /gene="gpmM"
                     /locus_tag="OPV72_001544"
                     /gene_synonym="pgmI"
     CDS             14489..16033
                     /gene="gpmM"
                     /locus_tag="OPV72_001544"
                     /gene_synonym="pgmI"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HCR9913889.1"
                     /translation="MSVSKKPMVLVILDGYGYREEQQDNAILNAKTPVMDALWAKRPH
                     TLIDASGLEVGLPDRQMGNSEVGHVNLGAGRIVYQDLTRLDVEIKERTFFANPVLTNA
                     VDQAKNAGKAVHIMGLLSAGGVHSHEDHIMAMVELAAERGAEKIYLHAFLDGRDTPPR
                     SAEASLKKFEDKFAALGKGRVASIVGRYYAMDRDNRWDRVEKAYDLMTLAQGEFQADT
                     AVAGLQAAYARDENDEFVKATVIRAEGQADAAMEDGDTLIFMNFRADRAREITRAFVN
                     ADFDGFARKKVVNLNFVMLTEYAADIKTAVAYPPASLANTFGEWMAKNDKTQLRISET
                     EKYAHVTFFFNGGVEEPFAGEERILINSPKVATYDLQPEMSSAELTEKLVAAIESGKY
                     DTIICNYPNGDMVGHTGVMEAAIKAVEALDNCIEQVTKAVESVGGQLLITADHGNAEQ
                     MRDPATGQEHTAHTNLPVPLIYVGEKNVKAVEGGKLSDIAPTMLSLMGMEIPQEMTGK
                     PLFIVE"
     gene            16043..17326
                     /gene="envC"
                     /locus_tag="OPV72_001545"
     CDS             16043..17326
                     /gene="envC"
                     /locus_tag="OPV72_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein hydrolase activator EnvC"
                     /protein_id="HCR9913890.1"
                     /translation="MRGKAINTIQQAVKPRTFSVRPLFYASVLSAGVLLCAFSAHADD
                     RDQLKSIQADIAAKERDVRQQQQQRASLLAQLKTQEEAISAAARKLRETQSTLDQLNA
                     QIDEMNASIAKLEQQKASQERNLAAQLDAAFRQGEHTGIQLILSGEESQRGQRLQAYF
                     GYLNQARQETIAELKQTREQVATQKAELEEKQSQQQTLLYEQRAQQAKLEQARNERKK
                     TLAGLESSIQQGQQQLSELRANESRLRNSIARAEAAAKARAEREAREAQAVRDKQQEA
                     SRKGSTYKPTESERSLMSRTGGLGAPRGQAYWPVRGPILHRYGERLQGELRWKGMVIG
                     ASEGTEVKAIADGRVILADWLQGYGLVVVVEHGKGDMSLYGYNQSALVSVGAQVRAGQ
                     PIALVGSSGGQGRPSLYFEIRRQGQAVNPQPWLGR"
     gene            17330..18292
                     /locus_tag="OPV72_001546"
     CDS             17330..18292
                     /locus_tag="OPV72_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divergent polysaccharide deacetylase family
                     protein"
                     /protein_id="HCR9913891.1"
                     /translation="MPQFRRSILTLATLLAFAHPVFAGKLAIVIDDFGYRPHTENQVL
                     ALPPNISVAVLPNAPHAREMATKAHNSGHEVLIHLPMAPLSKQPLEKDTLRPDMSSDE
                     IERIIREAVNNVPYAVGLNNHMGSAMTSSLFGMQKVMQALEHYNLYFLDSMTIGNSQA
                     MRAASGTGVKVIKRKVFLDDTQNEADIRRQFNRTIELARRNGSAIAIGHPHPATVRVL
                     QQMVYRLPADITLVRPGSLLNEPQVDTSRPDLTPQKIDAPRNPFRGVKMCKPKKPLQP
                     VYATRFFSVIGESITQSSVIVWFQHQWQGWGKIAAPKNMSAKTD"
     gene            complement(18279..19313)
                     /locus_tag="OPV72_001547"
     CDS             complement(18279..19313)
                     /locus_tag="OPV72_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCR9913892.1"
                     /translation="MKNSKTKVSIIIPLYNAGADFNACMASLIAQTWSALEIIIVNDG
                     STDHSIEIAKHYAEHYPHVRLLHQANAGASVARNLGLQAATGDYVAFVDADDLVYPKM
                     YETLMTMALNDDLDVAQCNADWCVRKTGHAWQSIPTDRLRSTGVLSGPDWLRMALASR
                     RWTHVVWMGVYRRALITDNNITFVPGLHHQDILWSTEVMFNATRVRYTEQSLYKYFLH
                     DNSVSRLQRQGNKNLNYQRHYIKITRLLEKLNRDYARRIPIYPEFRQQITWEALRVCH
                     AVRKEPDILTRQRMIAEIFTSGMYRRMMANVRSAKAAYQTLLWSFRLWQWRDKTLSHR
                     RMARKALNLS"
     gene            complement(19808..20833)
                     /gene="tdh"
                     /locus_tag="OPV72_001548"
     CDS             complement(19808..20833)
                     /gene="tdh"
                     /locus_tag="OPV72_001548"
                     /EC_number="1.1.1.103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HCR9913893.1"
                     /translation="MKALSKLKAEEGIWMTDVPEPEVGHNDLLIKIRKTAICGTDVHI
                     YNWDEWSQKTIPVPMVVGHEYVGEVVGIGQEVKGFKIGDRVSGEGHITCGHCRNCRGG
                     RTHLCRNTTGVGVNRPGCFAEYLVIPAFNAFKIPDNISDDLASIFDPFGNAVHTALSF
                     DLVGEDVLVSGAGPIGVMAAAVAKHVGARHVVITDVNEYRLELARKMGVTRAVNVAKE
                     SLNDVMAELGMTEGFDVGLEMSGAPPAFRTMLDTMNHGGRIAMLGIPPSDMSIDWTKV
                     IFKGLFIKGIYGREMFETWYKMAALIQSGLDLSPIITHRFSVDDFQKGFDAMCSGQSG
                     KVILSWD"
     gene            complement(20843..22039)
                     /gene="kbl"
                     /locus_tag="OPV72_001549"
     CDS             complement(20843..22039)
                     /gene="kbl"
                     /locus_tag="OPV72_001549"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HCR9913894.1"
                     /translation="MRGDFYKQLTNDLETARAEGLFKEERIITSAQQADITVADGSHV
                     INFCANNYLGLANHPELINAAKAGMDSHGFGMASVRFICGTQDSHKALEQKLASFLGM
                     EDAILYSSCFDANGGLFETLLGAEDAIISDALNHASIIDGVRLCKAKRYRYANNDMVE
                     LEARLKEAREAGARHVLIATDGVFSMDGVIANLKGVCDLADKYDALVMVDDSHAVGFV
                     GENGRGSHEYCDVMGRVDIITGTLGKALGGASGGYTAARKEVVEWLRQRSRPYLFSNS
                     LAPAIVAASIKVLEMVEAGAELRDRLWANARQFREQMSAAGFTLAGADHAIIPVMLGD
                     AVVAQKFARELQKEGIYVTGFFYPVVPKGQARIRTQMSAAHTPEQITRAVDAFTRIGK
                     QLGVIA"
     gene            22242..23174
                     /gene="rfaD"
                     /locus_tag="OPV72_001550"
     CDS             22242..23174
                     /gene="rfaD"
                     /locus_tag="OPV72_001550"
                     /EC_number="5.1.3.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-glyceromanno-heptose 6-epimerase"
                     /protein_id="HCR9913895.1"
                     /translation="MIIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLVD
                     LNIADYMDKEDFLIQIMSGEELGDIEAIFHEGACSSTTEWDGKYMMDNNYQYSKELLH
                     YCLEREIPFLYASSAATYGGRTSDFIESREYEKPLNVYGYSKFLFDEYVRQILPEANS
                     QIVGFRYFNVYGPREGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVA
                     AVNLWFLESGKSGIFNLGTGRAESFQAVADATLAYHKKGSIEYIPFPDKLKGRYQAFT
                     QADLTNLRNAGYDKPFKTVAEGVTEYMAWLNRDA"
     gene            23177..24223
                     /gene="rfaF"
                     /locus_tag="OPV72_001551"
     CDS             23177..24223
                     /gene="rfaF"
                     /locus_tag="OPV72_001551"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001728214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-heptose--LPS heptosyltransferase RfaF"
                     /protein_id="HCR9913896.1"
                     /translation="MKILVIGPSWVGDMMMSQSLYRTLKARYPQAIIDVMAPAWCRPL
                     LSRMPEVNEAIPMPLGHGALEIGERRRLGHSLRERRYDRAWVLPNSFKSALIPFFANI
                     PHRTGWRGEMRYGLLNDARVLDKDAWPLMVERYVALAYDKGVMRTAKDLPQPLLWPQL
                     QVSEGEKSLMYSDFSLSSERPLIGFCPGAEFGPAKRWPHYHYAELAKQLINEGYQVVL
                     FGSAKDHEAGNEILAALNSEQQAWCRNLAGETQLEQAVILIAACKAIVTNDSGLMHVA
                     AALDRPLVALYGPSSPDFTPPLSHKARVIRLITGYHKVRKGDTAQGYHQSLIDITPQR
                     VLEELHSLLSEEGV"
     gene            24223..25176
                     /gene="rfaC"
                     /locus_tag="OPV72_001552"
     CDS             24223..25176
                     /gene="rfaC"
                     /locus_tag="OPV72_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide heptosyltransferase RfaC"
                     /protein_id="HCR9913897.1"
                     /translation="MRVLIVKTSSMGDVLHTLPALTDAQQAIPGIQFDWVVEEGFAQI
                     PSWHSAVDRVIPVAIRRWRKAWFSAPIKAERIAFHRAVCAYQYDAVIDAQGLVKSAAL
                     VTRLAHGIKHGMDWSTAREPLASLFYNRKHHIAKQQHAVERTRELFAKSLGYDKPQSQ
                     GDYAIAKHFLHCQQAVSDPYAVFLHATTRDDKHWPEANWRELIGLVGNTGLRIKLPWG
                     APHEEARAKRLAEGFDYVDVLPRMSLEEVARVLAGAKFVVSVDTGLSHLTAALDRPNI
                     TLYGPTDPGLIGGYGKNQMACCSPEQNLANLDATSVFGKIH"
     gene            25216..>25507
                     /locus_tag="OPV72_001553"
     CDS             25216..>25507
                     /locus_tag="OPV72_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase RfaL"
                     /protein_id="HCR9913898.1"
                     /translation="MLTTSLTLNKEKWKPIWNKALVFLFVATYFLDGITRYKHLIIIL
                     MVITAIYQVSRSPKSFPPLFKNSVFYSAAVLSLILVYSILISPDMKESFKEFE"
BASE COUNT         6052 a         6939 c         6699 g         5817 t
ORIGIN      
        1 gatgccctgt tatgggatgc tgactctggc acattcagcg ccagccgtaa cggaagcgcc
       61 agcaaaatca ccaatctggc ggcgggtacc ctggccgcgg acagtacaga cgccgttaac
      121 ggctcacaat tgtatgaaac caaccagaag gtggatcaaa acacctctgc tatcgcagat
      181 attaatacgt ccatcaccaa tcttagctct gacaacctga gctggaatga aacaacgaat
      241 tcgttctctg ccagccacgg aagtagtacg acaaacaaaa tcaccaacgt tgctgccgga
      301 gagctgtctg aagaaagtac cgacgcggtt aacggatcgc agttgttcga aaccaatgaa
      361 aaagtggatc agaacacgac cgatatcgcc gccaatacca ccaacatcac tcagaacagc
      421 accgcgattg agaacctgaa tacttctgtc tccgacatta atacgtccat taccggcctc
      481 actgataacg ctctgttatg ggacgaagac accggcgctt tcagcgcaaa ccacggtgga
      541 agcaccagta aaataaccaa tgtcgccgcc ggggcgcttt ctgaggacag tacagacgcg
      601 gtaaacggat cacagttgta tgaaaccaac cagaaggtgg atcaaaacac ctctgctatc
      661 gcggatatca atacgtccat caccaacctt ggtaccgatg cactgagctg ggatgacgaa
      721 gagggtgcgt tcagcgccag ccacggtacc agcggtacca ataagataac taatgtagca
      781 gcaggtgaaa tcgccagtga cagtactgac gccattaatg gctctcagct ctatgaaact
      841 aacatgctga tttctcagta taatgaatct attagccaac tagccggcga taccagcgaa
      901 acctatatca cggaaaatgg taccggcgtg aaatacatcc gtacgaatga taacgggctt
      961 gaaggccagg atgcatacgc aacgggtaac ggcgcaacgg cagtaggtta cgacgccgtc
     1021 gcctctggcg ctggctgtct ggctcttggc caaaacagca gcagcagcat tgagggcagt
     1081 atcgctttgg gcagtggctc cacctctaac cgcgctatta caaccggtat acgagaaacg
     1141 agcgcaacaa gcgatggcgt ggtgattggc tacaatacaa cagacagaga gttgctgggc
     1201 gcgttgtcat tggggacgga tggagaaagc tatcgtcaaa ttaccaacgt tgctgacggc
     1261 tctgaagcgc aagatgcggt aacagttcgt cagttacaaa atgccattgg tgcggtcact
     1321 actacaccga ccaagtacta ccacgcaaac tcaacggaag aagattcact ggctgtcgga
     1381 actgactcac tggcaatggg tgcgaagact atcgtcaatg ctgatgcagg tattggtatt
     1441 ggtctgaata cactggtgat ggctgatgcc atcaacggga ttgctatcgg ttctaacgca
     1501 cgcgccaacc atgcaaacag tattgcaatg ggtaatggtt ctcagaccac tcgcggtgca
     1561 cagactgact acaccgccta caacatggac acaccgcaga actctgtcgg tgagttctct
     1621 gtcggcagtg aagacggtca acgtcagatc actaacgtcg cggcgggttc ggcagatacc
     1681 gatgccgtta acgttggtca attgaaagta acggacgcgc aggtttccag gaatacccag
     1741 agcattacta acctgaatac tcaggtatcg aatctggata cccgcgtcac caatatcgaa
     1801 aacggcattg gcgatatcgt cactaccggt agcaccaagt acttcaagac caacaccgat
     1861 ggcgcagatg caaatgccca gggtgcggac agcgtcgcga ttggctctgg ctctattgct
     1921 gccgctgaaa acagcgtggc gttaggcaca aattccgtcg cagatgaagc taatactgtg
     1981 tctgtcggct cttctactca acaacgccgt attaccaacg ttgccgcagg ggtgaacaac
     2041 actgacgcgg ttaatgtggc gcaactgaaa gcctcagaag caggctccgt gcgttatgaa
     2101 accaatgcag atggctcggt taactatagc gtgctcaact tgggagacgg gagtggcggc
     2161 accactcgga tcggcaatgt ttcagcggcg gtgaatgata cggatgcggt taactatgcg
     2221 caattgaaac gcagcgtcga agaagcaaac acctataccg accagaaaat gggggaaatg
     2281 aacagcaaaa tcaaaggcat agaaaacaag atgagcggcg gtatcgcttc agcgatggcg
     2341 atggccggtc tgccacaagc ctacgccccg ggcgccaaca tgacctcgat tgctggcggt
     2401 acgtttaatg gtgaaagtgc cgtcgccatt ggtgtctcca tggtaagtga aagcgggggc
     2461 tgggtgtata aactgcaagg aaccagcaac agccagggcg attactctgc agccattggc
     2521 gcgggcttcc agtggtaatg aagtaacaac actcccgaca tcaaaggcaa tggcataatg
     2581 ccattgcctt ttcacttccc tttgtggtcc tctcctctca attggcccta ccaattttag
     2641 ccagttacca cagcctactc acatttcact aaattaactc tacaatatcg ttgccaataa
     2701 ataacatccg gttaactatt tgttgtcatt atccatacac aacaatattg gcaggaccac
     2761 ttttacacat aatgtgactt caactagatg agcaaagatt catcccatta tgcgtgtggt
     2821 tctcaggaga cctgcaatga acctctggca acaaaactat gacccggcgg gtaatatctg
     2881 gctttccagc ctgatcgcat cgctcccaat cctgttcttc tttttcgccc tgattaaact
     2941 caagctgaaa ggctatgttg ccgcttcgtg gacggtggtt atcgcgctcg ccgtcgcgct
     3001 gctgttctat aaaatgccgg tcgatcacgc gctggcatcg gtcgtgtatg gcttcttcta
     3061 cgggctatgg ccgatagcct ggataatcat cgccgcggtc tttgtctata aaatttcggt
     3121 caagaccggg cagtttgaca ttattcgctc gtcaattctg tcgattaccc ccgaccagcg
     3181 tctgcaaatg ctgattgtcg gcttctgctt cggcgcgttc cttgaaggcg cggcgggttt
     3241 cggcgcgccg gtggcgataa ccgctgcgct gctggtgggc ctgggcttta accctctgta
     3301 tgcggcaggg ctgtgcctga ttgtaaacac cgcgccggtc gcctttggcg cgatgggtat
     3361 tccgattctg gttgccggac aggtcacgga cctggacagc tttgaaatcg gtcagatggt
     3421 aggccgccag ttgccgttcc tgaccattat cgtgctgttc tggattatgg cgattatgga
     3481 cggctggcgc ggcgtgaaag aaacctggcc tgcggtgatg gtcgctggcg gctcgtttgc
     3541 tatcgcccag tatctcagct ccaactttat cgggccggaa ctgccggaca tcatctcttc
     3601 actggtgtct ctggtgtgtc tgacgctgtt cctcaaacgc tggcagccgg tacgcatctt
     3661 ccgcttcggc gatatgggcg cgtcgcaggt cgatcagacg ctggcccgca cccgttatac
     3721 gacaggacaa attgttcgcg cctggtcgcc gttcctgttc ctgaccgcca cggtcacgct
     3781 ctggagcata ccgccgttca aagcgctgtt tgcccccggc ggcgcgctgt atgactgggt
     3841 aattaacgtt ccggtaccgt atctcgataa actggtcgcc cgtatgccgc cggtcgtaca
     3901 cgaagcgacc gcttacgcgg cggtgtataa atttgactgg ttctccgcca ccggcactgc
     3961 gatcctgttt gccgcgctgt tgtctattgt ctggctgaaa atgaaaccct cagccgcaat
     4021 ccagaccttt ggcagcacgc tgaaagagct ggcgttgccg atttactcca tcggcatggt
     4081 gctggcgttc gcgtttatct cgaactattc cgggctttcc tccacgctgg cgttagcgct
     4141 ggcgcacacc ggcagcgcct tcacgttctt ctcgccgttc ctcggctggc tgggcgtctt
     4201 cctgaccggc tcggatacct catctaacgc gctgtttgcc tctctacagg ctaccgcggc
     4261 gcagcaaatc ggcgtctctg atgtactgat ggtggcggcg aacaccactg gaggcgtaac
     4321 cgggaagatg atctcgccgc agtctatcgc catcgcctgc gcggcggtgg gactggtagg
     4381 gaaagagtcc gatctgttcc gttttaccgt caaacacagc ctgatcttca cctgtatggt
     4441 gggcgtgatc actacgcttc aggcctatgt tttaacctgg atgattccgt gattgtgatg
     4501 ccaaaacgcc tgtcagacga gattgcctct cgcgtgcggg cgctgattga agaacaaaac
     4561 ctggaagcgg gcatgaaatt gcccgccgag cgccagttgg ctctacagct tggcgtatca
     4621 cgcaactctt tacgcgaagc gctggcgaag ctggtcagcg aaggcgtgct ggtgagccgt
     4681 cgcggcggcg ggacatttgt ccgctggcag cacgaaacct ggtctgaaca gaatatcgtg
     4741 caaccgctga aaatgctgat ggcgaacgat ccggactaca gtttcgacat tctggaagcc
     4801 cgccacgcca ttgaagccag tacggcctgg cacgccgcca tgcgtgccac cgccgccgac
     4861 aaagagaaaa tcagactctg ctttgatgcg acgctcagcg aagacccgga tctcgcctcc
     4921 caggccgacg tgcgctttca tctggcgatc gcggaagcct cgcataatgt ggtgctgttg
     4981 caaaccatgc gcggtttctt cgacgtcctg caatcctccg tcaaacagag tcgccagcgt
     5041 atgtatctcg ttccgcccgt attctcaaag ctgacggaac aacaccaggc ggtgttggac
     5101 gccattctgg acggtaacgc cgagggcgcg cgtaaagcga tgatggcgca cctcagtttt
     5161 gtccacacca cgattaaacg atttgatgaa gaccaggccc gccaggcgcg cattacccgc
     5221 ctgcccggcg accataatga gatgaccagg gagaataaat catgattatt tcagcaacca
     5281 gcgattatcg cgccgcagct cagcgcacgt tgcctccttt cctcttccac tacatcgacg
     5341 gcggcgcgta tgcggaatat accctgcgcc gaaatgtgga agacctgtcg caagtcgctc
     5401 tgcgccagcg cgtgctgaaa aatatgtccg atttaagcct ggaaacgacc ctgtttaacg
     5461 aaacgttgtc gatgccggtg gcattagcgc cggtaggtct gtgcggcatg tacgcccgtc
     5521 gcggcgaagt acaggccgcc gccgccgcag acgcaaaggg cattccgttc accctttcca
     5581 ccgtctccgt ctgtccgatt gaagaagtag cccccacgct taaacgcccg atgtggttcc
     5641 agctttatgt actgcgtgac cggggcttta tgcgtaatgc gctggaacga gcaaaagcgg
     5701 cgggctgctc cacgctggtc tttaccgtgg atatgccgac gccgggcgcg cgctaccgtg
     5761 acgcccactc cgggatgagc ggcccaaacg cggccatgcg ccgttactgg caggcggtga
     5821 tgcaccctaa atgggcgtgg gatgtcggcc tgaacggtcg cccgcatgat ttaggcaata
     5881 tttccgccta tctgggtaaa ccgaccggcc ttgaggacta tatcggctgg ctggcaaata
     5941 acttcgatcc gtccatctcc tggaaagatc tggagtggat acgcgaattc tgggacggcc
     6001 caatggtgat caaagggatc ctcgatccag aagatgcccg cgatgcggta cgtttcggcg
     6061 ctgacggtat cgtggtgtcg aatcacggcg gccgccagct cgatggcgtg ctctcttccg
     6121 cccgcgccct gcccgccatt gccgatgcgg tgaaaggcga tatcgccatt ctggcggata
     6181 gcgggattcg taacgggctg gatgtcgtgc gtatgattgc gctgggggcc gataccgtac
     6241 tgctgggtcg ggcctatctc tacgcgctgg cgacggcagg aaaaactggc gtcgctaacc
     6301 tactggacct gatcgagaaa gagatgaaag tcgccatgac cctgaccggc gcgaaatcca
     6361 ttagcgaaat cagtggcgat tcactggtgc aggaactggg gaaaagtttg cccgccgcgc
     6421 tggcgccaat gagcaaaggc gatgccgcct gaacgtctgg cgcgtgagag cccggtaaat
     6481 ttctgctatt ctgccccccg catttaaggg ggcatcatgc ttaacatcgt actcttcgaa
     6541 ccagaaatcc cgccgaatac cggcaacatc attcgtcttt gcgccaatac cggctttcgt
     6601 ctgcacatca tcgaaccgat ggggtttgcc tgggatgata agcgcttacg ccgcgcaggg
     6661 ttggactatc acgaattcgc cgcggttcag cgccatcacg attatgccgc ctttgtcgcc
     6721 gccgaaaatc cacagcgcct gtttgcgttg acgacaaagg gcacgcccgc ccatagcgcc
     6781 gtaagctatc aggatggcga ttatttgatg tttggcccgg aaacgcgcgg cctgcccgcc
     6841 agcattctcg atgcgttgcc taaagagcag aagattcgca ttccgatgat gccggatagc
     6901 cgtagcatga acctgtcgaa tgcggtgtcg gtggtggtgt atgaagcgtg gcgccagtta
     6961 ggataccccg gcgcggtatt gcggtcgtaa tatattcaat gccggatggc ggctaacgcc
     7021 tgatccggcc tggccgatcc cgatggcatg ttcccgttta tgcggactct cgctcaatca
     7081 aatgaaagcc aatatccaca atagcttctg cgcacggttt ctgttcaata cgatcggcca
     7141 acagcgtagc ggcgcgctga ccaatggcgc gtctgtcaac gcttacggta gtaattgacg
     7201 gtcgattgct ggcggcaaaa tcaaggtcgc caaaaccaat aaccgctaaa tcatgcggga
     7261 tgcgcaaacc acggctttcc gcctccatca tcgccccctg tgccagggta tcagaactgc
     7321 aaacaatgac atcaaacgtc ccttcgtcaa aaagctggct taaaccgcta cgccccagcg
     7381 aaagcgatgc cggaaggggg acatccacct gcggtacggc atgaatagcg tggcgttgaa
     7441 gaacactaca taacccctgc ttacgttgcg cggctcggcg atcggcggtc cacaacaagc
     7501 cgggacgacg atagccctta ctcagaagat actcccccgt cgcctgcccg actttttcat
     7561 gggaaaaacc gaccagcata tcaagcggcg tgggcgttaa gtcccaaatt tccaccaccg
     7621 gaatagccgc gttcaggatg acctttttca gttctatcgt gtgatggatc ccggtaagca
     7681 ccacgccatc ggggcggcgg gaaagcagtg tcgccaccaa ctccgcttcc gtttgttcgg
     7741 tatatcccgc cacgcacagc aatatgtgat atccgcgtcg ggccagttca tcgctcagtg
     7801 actggatggt atcgacaaac atgttgttgt taatttgcgg cacgacgaca gcgattaatt
     7861 tactccgtcg cgacgccaga ccaccggcta acgcgttggg tatgtagcct gtgacgcgaa
     7921 ccgcctgcat gactttctca accgttttgg ggcgaaccag ttgtggcgaa ttcaatgccc
     7981 ggctgactgt catcggagac agcccggcgc tacgtgctac atcttccagc gtcggcgcac
     8041 gaggtgattt ggttctcttc acgtctgatg cccctgcaaa gattggctga tttatccgcg
     8101 cattattcat catgcctgcg gctattgcca gcttcgcatc aggaaaggcc gtaaatacag
     8161 tagcttatca agctcagtca ttacaaaatg atagcgacat cattttgtat tatgcatttc
     8221 cccagatatt tttggatcgt gatccatttt gcaataaatc ctgcttttta tacgacatat
     8281 gtgatcaaat gttcaaatca acatcaactt tctggatcct gcgttcgctt aataataaaa
     8341 atgttagcgc aatcattttg tgtttatcag gagaaaaaaa atggctttaa gcgcgaattc
     8401 cgacgccgta acgtatgcaa aagcggcgaa taccagaacc gcggcagaaa ccggcgatcg
     8461 tatcgaatgg gtgaagctat cactggcttt tctaccgctg gcgacgccag tgagtgacgc
     8521 gaaggtactg accggtcgcc agaaaccttt gaccgaagtg gcaatcatca ttgccgaaat
     8581 ccgcagtcgc gatggctttg agggcgttgg ttttagctac tccaaacgtg ctggcggcca
     8641 gagtatttat gctcacgcca aagagatagc cgacaatcta ctgggcgaag accccaatga
     8701 tatcgacaaa atatacacca agctgctgtg ggccggagcc tcggtggggc gtagcgggat
     8761 ggcggtacag gctatctccc ctatcgatat cgccttatgg gatatgaagg ctaaacgtgc
     8821 cggtctgcca ctggcaaaac tgttgggcgc gcaccgcgac tccgttcagt gttacaacac
     8881 ctcagggggg ttcttgcata caccgctcga tcaagtgctg aaaaatgtgg tgatttcccg
     8941 cgaaaatggc attggcggta ttaagttgaa agtcggacaa cccaactgcg ctgaggatat
     9001 tcgccgctta accgcagtac gtgaagcgct tggggatgag ttcccgttaa tggttgacgc
     9061 taaccagcag tgggatcgcg aaacggctat ccgcatgggg cgtaaaatgg aacagttcaa
     9121 tcttatctgg attgaagaac cattagatgc ttacgacatc gaaggccacg cccagcttgc
     9181 tgccgcgctg gatacgccta tcgccaccgg ggaaatgctg accagtttcc gggaacacga
     9241 gcagttgatt ctgggcaatg ccagcgattt cgttcagcca gatgcgccgc gtgtcggcgg
     9301 tatctctccg ttcctgaaga ttatggatct ggcggcgaaa cacgggcgta agctggcgcc
     9361 gcactttgcg atggaagtac acctgcacct ttccgcagcg tatcccctgg agccgtggct
     9421 ggaacatttc gagtggctga acccattatt caacgagcaa cttgagctgc gcgatggccg
     9481 catgtggatt tccgatcgtc atggtctggg tttcacgctc agtgaacaag cgcgccgctg
     9541 gacacaatta acatgtgaat ttggcaaacg cccttaaccc gactggcggg aatccgtccc
     9601 gcctctctta ccttacagga tgcattctgc ccttatctga ggagtagata atgaacacaa
     9661 taataaagtg cacaaaagtg cgtcatacca ttcttatatt tttatttctt gctaccgtat
     9721 ttaattatgc ggatcgcgca actctatccg tagttgcccc aataatgagt aaagaattag
     9781 gttttgatcc ggaagcgatg ggcctggcct tctcctcatt tggtattgcc tatgtcatta
     9841 tgcaactacc cggcggttgg ctattagacc gctacggttc acgactggtt tacggttgcg
     9901 cattgattgg ctggtcgtta gtaaccatgt ttcagggaac gatctatctg tatggcagcc
     9961 cattaattgt actggttact ctacgtctgc tgatgggcgc gattgaagcg cctgcctttc
    10021 cggcgaacag tcgtttaagc gtacaatagt ttcccaataa tgaacgaggt ttcgttactt
    10081 cagtttatca ggctgcgcaa tatatctcgc tgggcattat caccccgcta atgacgatca
    10141 ttctgcataa tttaagctgg cattttgtct tctattatat tggcgccatt ggtgtgatgt
    10201 tcggtatatt ctggttaatg aaagtcaaag atccgatgca ccactcaaaa gttaatcaag
    10261 cggaaattga ctatattcgt agcggtggtg gcgagccctc tctgggctgt aaaaaggagc
    10321 cgcagaaaat aacgttcgcg cagattaaaa ccgtctgtgt taaccggatg atgatcggtg
    10381 tttacatcgg gcaattctgc gtcacctcta tcacctggtt cttcctgacc tggttcccga
    10441 cctatctgta ccaggcgaaa ggcatgtcga ttctgaaagt cggttttgtg gccagtattc
    10501 cagccattgc cggttttatt ggcggcctgc tcggcggcgt gttctccgac tggctactca
    10561 aacgcggcta tagccttacc gtcgcgcgga aactgcctgt tatctgcggt atgttgctct
    10621 cttgcgtaat tgtgatcgcc aactacacct cttcagaatt tgtggtcatt gcggcgatga
    10681 gtctggcctt ttttgccaaa gggtttggta acctgggctg gtgcgtactc agcgacacct
    10741 cgccgaagga agttctgggt attgctggcg gcgtatttaa catgtgcggc aatatggcaa
    10801 gcatcgttac gccactggtc atcggcgtga ttcttgccaa tactcagtcg ttcgactttg
    10861 ccattttata cgttggctcg atgggactta ttggtctcat ttcatatctg tttatcgtcg
    10921 gcccgctgga tcgcatcacg ctgacatcat ccgcagcctg attgtccaca ttgcgaattc
    10981 ttcgctccgc tgttccggga ttgcactcca tcggaacagc gttttttagt tgtaccgcgc
    11041 aattcagatg ccgtcgccat actcaaacgt atggtgtagc ccgttgaaat gctggtccat
    11101 atccatcgac ggcttatcgc tgcccggctt gccgacaata cgcgccggaa cgcctgcggc
    11161 ggtagtgtgc ggcgggacag gctgtaaaac gacggagcct gcgccaattt tcgcgccgcg
    11221 ccccacctcg atattgccga gaattttcgc gcccgcgcca atcatcacgc cttcgcggat
    11281 tttaggatgg cgatcgccgc tcgttttccc ggtaccgccc agggtgacgg attgcaggat
    11341 cgacacatca tcctcaataa ccgccgtctc ccccaccaca ataccggtgg catggtcgag
    11401 cataatcccg cggccaattt tcgctgccgg gtgaatatcc acctgaaacg agaccgaaac
    11461 ctgattttgc aggaagatag ccagcgcgcg gcgaccttta ttccacaacc agtgaccaat
    11521 gcggtaggcc tgtagcgcat gaaagccttt cagatataac agcggcgtgg agtatttatc
    11581 caccgccgga tcgcgagtgc gcacggcctg aatatcgcag gctgccgacg cgatcatttc
    11641 cgggtcggcg gcataggctt cttcaactac ttcacggata gcgatagcgg gcatgatggg
    11701 cgaagccagt ttatttgcca gcatatagct cagcgcactg cccagatttt catgcttgag
    11761 tagcgtggcg tgataaaaac tggccaacat aggctcacag tcagctaaag cgcgggcttc
    11821 agctttaata ttcttccaga cgatttccag ttcttcacac ggcatggctt actccagacg
    11881 ggcagaaaac gaccaacccg ttctgtgcgg gttgggtcgt ttatgcaaac agttccttac
    11941 ggctagtggc gactcagctc ttccttgcgg gcgcgaccta ataacgttaa tgctgcctcg
    12001 cgcgcgtttt ttccgcaata caatacttga taaatttcct cggttattgg catttcaaca
    12061 ccaaaacggt gcgccaattc acgaacttct ttcgtattgc gatagccttc gaccacctgg
    12121 ccaatcttat cctgcgcgcc tttaacgtcc atgccctggc caagcatcat gccaaaacga
    12181 cggttgcgcg actggttgtc ggtacaggtc agcaccagat cgcctaaacc cgccatcccc
    12241 ataaaggtgg cgggatcggc accaagcgct gcgccaagcc gcgacatttc ggtcagtcca
    12301 cgcgtgatta gcgccgtgcg ggcgttcgcg ccgaagccga tgccgtcaga catccccgcg
    12361 ccaatcgcaa tcacgttttt caccgcgccg ccaagctgca cgccgataaa atccgcattg
    12421 atatagacgc gaaaactttt tccgcagtgc aacagttgct ggagatcgtc ggcaaaggtc
    12481 tcatcggttg aggctagcga gattgccgtc ggcaaacccg ccgccagctc tttagcgaac
    12541 gtcggaccgg aaatcaccgc cagcgggatt tgatcgccta acgcctcgcg agcgacatcc
    12601 tgcaacaggc gccccgtttc cgcttccagg cctttggtcg cccataccag acgcgcatcc
    12661 ggacgcatca gcggtttaat ctgccgcagc acgtcgctga aaacatggct tggcaccacc
    12721 accagaatgt tacgactggc cgccagcgcg gttgctaagt cgctttccag gtgtaacgta
    12781 tcgggaaaag gcacatcggg aaggaacgcg acgttgcagc gatcgtgctc cagggtcgcg
    12841 atatgttttg ggtcgtggcc ccacaggaca acctggtggc cgtttctcgc cagagtgatg
    12901 gcgagagcgg tgccgtacga gccggcaccg atgactgtca ttgacgcatt actttggttc
    12961 atcaggcatc ctgatgttct tcagtacctt cgccagcctg ctgctgcaaa tagttcatga
    13021 acagcgcatc aaagttgacc ggcgcaaggt tcagttgcgg gaacgtaccg cgtgaaacca
    13081 gactggtgat gcactcgcga gcatacggga acagaatgtt cgggcagtat gctcccaggc
    13141 aatgcgccat ctgagtgcct tcaataccgc tgatggagaa aataccggcc tgctgaactt
    13201 cgcacaggaa cgcggtttct tcccccaggg aagccgttac ggtaacacgc agcacaactt
    13261 cataaacgtc atccgccagt tgggaagatg ccgtatcaag atctagttta acctctggct
    13321 gccaatcttt ctggaaaaca tgcggtgcgt ttggcgcttc gaaagaaaca tccttggtat
    13381 agatacgttg gatctggaaa gccatttcag tgttattttg ttctgacatg tgtaaaaccc
    13441 tttagtgttg tccttaaata cttgagtacg ccttaacgca acagcggatc cagtccacca
    13501 cgcgcatcca gcgcatacaa gtcgtcacaa ccgccaatgt gctgtgcatc aataaaaatt
    13561 tgcggaaccg tcgttcggcc actacgtttg atcatctctt cacgcttcac ggcgtcgccg
    13621 tcaatcgcaa tttcctggaa actcacgccc ttgctgttta acagcgcctt tgcacgatgg
    13681 caaaacgggc aggttgcttt ggtgtagatt tcaatattgg ccatgacttc gctcctgttt
    13741 tttacccgat ggatttcatg tcgacgcaag ggcaagtcat tccccttgcg tcatgaaaac
    13801 gacgggtaat cacttaccgc gcaccagagg cagattctcg ccgctccagc ctgctacgcc
    13861 ttctttcaac acaaagacct tttcaaagcc ggcttttgtc agcgcgttag cggattcctg
    13921 gcactgcata ccagaaccgt cgaccacgat aattggcttg tctttgtgct tttccagttc
    13981 gccaacattg ttggctttga tttcgctcgg cagcaaattg gtcgcgccag cgatatggcc
    14041 tttacggaaa tcgtcacgtt gacgtaaatc cacaacaacg gcgtcctctt tgttgataag
    14101 gcgcgtggct tcgccgcgtg taatcacctt aacttttgaa gtcagacctt tgaacgtggt
    14161 aaataaaacc gccaccagta acgcaatcca ggcgatactc agtatgggat gacggccaac
    14221 aaattgcata atttcttgca tggggggtaa caactcccga cgtagtgatt aaaaaaccag
    14281 gaaaggagta tacctgcgca gtggcgcaaa tacagccaga gcgtgcactg gaatgcattt
    14341 ttgcggggcg ctacgaaaaa aaatcacgct attacttgcc ttctcacgcc agcgcgatcc
    14401 ctttctttga tcttctgagg ctattttatc gattcagctg tagtaaaatt acgcaattat
    14461 tttgtctatt gagtatgagg ttgtcgcaat gtcggtttct aaaaaaccta tggtactggt
    14521 gattctggat ggctacggct accgtgaaga acagcaggat aacgctatct taaacgccaa
    14581 aaccccggtg atggatgctc tgtgggcaaa acgtccgcat accctgatcg acgcatccgg
    14641 tctggaagtg ggtctgcctg accgccagat gggcaactcc gaagtgggcc acgttaacct
    14701 gggcgcaggc cgcatcgttt atcaggacct gacgcgtctg gacgttgaaa ttaaagaacg
    14761 tactttcttt gctaacccag tcctgaccaa tgcggtagac caggcgaaaa acgccggtaa
    14821 agcggttcat attatgggtc tgctgtccgc gggcggcgtc cacagccacg aagatcacat
    14881 tatggcgatg gtggagctgg ccgcagagcg cggcgcagaa aaaatctatc tgcacgcctt
    14941 cctcgacggt cgcgacacgc cgccgcgcag cgctgaagcc tcgctgaaaa aattcgaaga
    15001 caaattcgcc gcgctgggca aaggtcgcgt ggcgtctatc gtcggtcgtt actacgctat
    15061 ggaccgcgac aaccgttggg atcgcgtgga aaaagcgtat gatctgatga ccctggccca
    15121 gggcgaattc caggcggata ccgctgtggc tggcctgcag gccgcttacg ctcgtgatga
    15181 aaacgatgag tttgtcaaag cgaccgttat ccgcgccgag ggccaggctg atgcggcgat
    15241 ggaagacggc gacacgctga ttttcatgaa cttccgcgct gaccgcgcgc gcgaaattac
    15301 ccgcgctttc gttaatgctg atttcgacgg ctttgcgcgt aagaaagtgg ttaatctgaa
    15361 cttcgtgatg ctgaccgaat acgccgccga tatcaaaact gccgttgcct acccaccagc
    15421 gtcgctggcg aatacctttg gcgaatggat ggcgaaaaac gacaaaactc agctgcgtat
    15481 ttccgaaacg gaaaaatatg cgcacgtaac ctttttcttt aacggcggcg tagaagaacc
    15541 gtttgctggt gaagagcgta ttctgatcaa ctcaccgaaa gtggccactt atgacctgca
    15601 accggaaatg agctctgcag aattgactga aaaattggtc gcggcgatcg aaagcggtaa
    15661 gtacgacacc atcatttgta actatccaaa cggcgatatg gtcggtcata ccggcgtgat
    15721 ggaagccgcc atcaaagcgg tggaagcgtt ggataactgc attgaacagg taacaaaagc
    15781 ggttgagtcc gttggtggac aactgttgat taccgcggac cacggcaacg cggagcagat
    15841 gcgcgatccg gcgaccggtc aggagcatac cgcccacacc aacctgccgg tgccgctgat
    15901 ttatgtcggc gagaaaaacg tgaaggcggt cgaaggcggc aaactttcag acattgcgcc
    15961 taccatgctg tcgctgatgg ggatggaaat cccgcaagag atgactggta agccgctgtt
    16021 catcgtggaa taatccctcc ccatgagggg aaaggcgatt aacaccattc aacaggccgt
    16081 gaaaccaaga acgttttcag tcaggccttt gttctacgcc agcgtactta gcgctggcgt
    16141 attgttgtgc gccttttccg cccacgcgga tgaccgtgat caactcaaat ctattcaggc
    16201 cgatatcgcc gcgaaagaac gcgacgtacg ccagcagcag caacagcgcg ccagcctctt
    16261 ggcacaactg aaaacccagg aagaggccat ctcggccgca gcgcgtaagc tgcgcgaaac
    16321 gcaaagcact ctggatcagt taaacgcgca aattgatgag atgaacgcct caattgccaa
    16381 actggagcag caaaaagcca gccaggagcg taatctcgct gcgcagttgg acgccgcttt
    16441 ccgccagggc gaacacaccg gcattcagct tattcttagc ggagaagaga gccagcgtgg
    16501 gcaacgcctg caggcctact tcggctatct gaaccaggcg cgccaggaga ctatcgccga
    16561 actgaaacag actcgcgaac aggtcgccac gcaaaaagcc gagctggaag agaagcaaag
    16621 ccaacaacaa acgttgctgt atgaacagcg cgctcagcag gcgaagctgg aacaggcgcg
    16681 taatgaacgt aagaaaacgc ttgccggact ggagtcgtct attcagcaag gccagcaaca
    16741 gttaagcgaa ctacgcgcca acgaatcacg cctacgcaac agtatcgcgc gggcggaagc
    16801 ggcggccaaa gcgcgagcgg agcgtgaagc ccgcgaagcg caggcggtac gcgataagca
    16861 gcaggaagcc tcgcgtaaag gcagcaccta taagccgacg gaaagcgagc gctcgctaat
    16921 gtcccgcacc ggcggtctgg gcgcgcctcg cggtcaggca tactggccgg tacgtggccc
    16981 gatattgcat cgttatggcg aacggctgca gggtgagcta cgttggaagg ggatggtgat
    17041 cggcgcgtcg gaaggcaccg aggtcaaagc catcgccgac ggcagggtga ttctggcgga
    17101 ctggctgcaa ggctatggcc tggtggtggt cgtggagcat ggtaaaggtg atatgagcct
    17161 ttacggctat aaccagagcg cgctggtcag cgtaggcgcg caggtgcgcg ccggacaacc
    17221 tatcgccctt gtgggcagta gcggcggtca gggcagacct tcgctttatt tcgaaattcg
    17281 tcgccagggt caggccgtca atccacagcc gtggttggga agataagttt tgcctcagtt
    17341 tcgtcgctcc attctcacgc tggccacttt gctggcattt gcacatcccg ttttcgctgg
    17401 caagctcgcc atcgtgattg atgattttgg ctatcgcccg cacacggaaa accaggttct
    17461 ggcgctgccg ccaaacatct ccgtcgctgt actgcccaac gcgccgcacg cgcgcgaaat
    17521 ggcgactaaa gcgcacaata gcgggcatga ggtgttaatc catctgccga tggcgccgct
    17581 aagcaaacag ccgctggaga aggatacgct gcgaccagat atgagcagcg atgagatcga
    17641 gcgcattatc cgcgaggcgg taaacaacgt gccgtatgcc gttgggctta ataaccacat
    17701 gggcagcgca atgacttcca gcctgttcgg tatgcaaaaa gttatgcagg cgctggaaca
    17761 ttacaatctc tattttctcg acagcatgac gattggcaat agccaggcga tgcgcgcggc
    17821 atccggtacg ggtgtgaaag tgatcaagcg caaagtgttc ctcgacgata cgcaaaacga
    17881 ggcggatatc cgtcgtcagt ttaatcgcac tatcgaactg gcccgtcgca acggttccgc
    17941 tatcgcgatt ggtcatccgc atcccgcaac ggttcgcgtg ctgcaacaga tggtttatcg
    18001 cctgccggca gatatcaccc tggtacgtcc aggcagcctg ctcaacgaac cgcaggtaga
    18061 tacgtctcga cctgatttga cgccgcagaa aattgacgcg ccgcgcaatc cctttcgcgg
    18121 cgtgaagatg tgcaagccga aaaaaccgct gcaaccagtc tacgctacgc gctttttcag
    18181 cgtcatcggc gagagcatta cgcaaagttc cgtgattgtc tggtttcagc accagtggca
    18241 aggctggggg aaaatcgccg cgcctaaaaa catgagcgct aagacagatt gagcgcctta
    18301 cgggccatac gacggtgcga caaggttttg tcgcgccatt gccacagccg gaaggaccag
    18361 agcagcgtct gataagccgc tttcgcgctg cggacgttag ccatcatccg tctatacatg
    18421 ccagaagtaa aaatttcggc aatcatacgc tggcgggtca aaatatcagg ttctttacgc
    18481 accgcatgac aaacgcgtaa cgcttcccag gtaatttgct ggcgaaactc cgggtaaatc
    18541 ggaatacgcc gggcataatc acgattgagc ttttctaata accgcgtaat tttaatataa
    18601 tgccgctgat aattaagatt tttattgcct tgtctttgca aacggcttac cgaattatca
    18661 tgcaggaaat atttatataa tgattgttcg gtataacgta cgcgcgtggc attaaacata
    18721 acttccgtcg accataatat gtcctgatga tgtagtccgg gaacgaaagt aatattgtta
    18781 tcggtaatta acgcacgtcg ataaacgccc atccagacaa catgcgtcca gcgtcgcgag
    18841 gccaatgcca tacgcaacca atccggtccg cttaataccc cggtggaacg cagacgatcg
    18901 gtcggaatag attgccaggc gtgcccggtt tttcggacgc accagtccgc attacactgc
    18961 gcaacgtcca gatcatcgtt aagcgccata gtcatcagcg tttcatacat cttcgggtag
    19021 accaggtcat ccgcatcgac aaaggcgaca taatctccgg tcgccgcttg caaaccaaga
    19081 ttacgggcga cagatgcgcc agcattggcc tgatgaagca gtcgaacgtg cgggtaatgt
    19141 tccgcgtaat gttttgctat ctcaatggaa tgatctgtcg atccatcatt cacaataata
    19201 atttccagcg ccgaccacgt ttgcgcgatt aacgacgcca tgcaagcatt aaaatccgct
    19261 cccgcattat ataacgggat aatgatactc actttggttt tactattttt cataacgatt
    19321 accagaaaaa ccttaattta ccctgccttt atactgtggc tctattaaga aactattaag
    19381 ccgccataat taatttttac agtaaaaagc aagcacaaaa ctcagagtag ggcgtgacgt
    19441 tagcgagtaa aataagatta aagcgcaatt acgaatgctt gatgtctatg acaattcttt
    19501 acagctttcc agattttccc taacaaaaaa ggttggcgaa tgacaccaac cttttacgat
    19561 gaaacgtata tcagacccga taaatatcat tgggtctcta tacccttcat acttcaagtt
    19621 gcttatgtgt tggctacgga ttactcggcc catctatggg cctcgccctg acgggccgtc
    19681 gcacgcgacg ttcaaatctg ctcccggcag atttgtcgtt caccccagtc acatagttat
    19741 ctatgctcct ggggactcac tcccttgccg cctttaagca actcgaatta ttttgggtat
    19801 atacatatta atcccagctc agaatgactt ttcctgactg gcctgaacac atggcgtcaa
    19861 aacctttctg aaaatcatca acagagaaac gatgggtgat aatcggtgac agatccagac
    19921 cggactggat cagcgccgcc attttgtacc acgtttcgaa catctcacga ccataaatac
    19981 ctttaatgaa caagccttta aagatgactt ttgtccagtc gatagacata tctgatggcg
    20041 gaatccccag catcgcaata cgaccgccgt gattcatggt gtccagcatg gtacgaaacg
    20101 ccggcggcgc gccggacatc tccagaccca catcaaaccc ttcggtcatt cccagctccg
    20161 ccatgacgtc gttcaggctc tctttcgcga cgttgaccgc gcgggtgacg cccattttgc
    20221 gcgccagctc cagacggtat tcattgacgt cagtaatcac cacatgacgc gcgccgacat
    20281 gtttcgccac cgcggcggcc attacgccga ttggccccgc ccccgatacc agtacatctt
    20341 cgccgaccag atcgaaagac agcgccgtat gcaccgcatt accaaacggg tcgaaaatag
    20401 aggctaaatc atcagaaatg ttatccggga ttttaaacgc attgaatgcc gggatgacca
    20461 ggtattccgc gaagcagccg ggacggttga cgcccacgcc ggtggtgttg cgacacaggt
    20521 gagtacgacc gccacggcag ttgcggcaat gaccgcaagt gatgtgacct tcgccggaga
    20581 cgcgatcgcc gattttaaag cctttcactt cctgaccgat gccgaccact tcgccgacat
    20641 attcatgccc cacgaccatc ggaaccggga tggttttttg cgaccattca tcccagttat
    20701 agatgtgaac gtcagtgccg cagatggctg ttttacggat tttaatcagc aaatcgttat
    20761 ggccgacttc cggttccgga acgtcggtca tccagatgcc ctcttccgct ttcagtttgg
    20821 ataacgcttt catcttacat cctcaggcaa tcacgcccag ttgtttacca atacgcgtga
    20881 acgcgtctac cgcacgcgta atttgctcag gcgtatgcgc cgcagacatc tgggtacgaa
    20941 tacgcgcctg accttttggt acgaccggat agaagaaacc ggtaacgtaa atgccctctt
    21001 tttgcagttc gcgggcaaat ttctgcgcga caaccgcatc tcccagcatt accgggatga
    21061 tggcgtgatc cgcgcctgcc agcgtaaatc ccgcggcaga catctgctca cggaactgcc
    21121 gggcgttcgc ccacaagcga tcgcgcagtt ctgcgcccgc ttccaccatc tccaacactt
    21181 taatagaagc cgccacgatt gccggcgcca gggagttgga gaacagatat gggcgggaac
    21241 gctgacgcaa ccactcaacg acctctttac gcgccgcggt atagccgccg gatgcgccgc
    21301 ctaacgcttt gcccagcgta ccggtaataa tatctacgcg gcccattacg tcgcagtatt
    21361 catgggaacc gcgaccgttt tcgccgacaa agcctaccgc gtgagaatca tcaaccatca
    21421 ccagcgcatc gtatttatcg gccagatcac agacgccttt cagattggcg atgacgccat
    21481 ccattgagaa caccccgtcg gtggcgatca ggacatgacg cgcgccggct tcacgcgcct
    21541 ctttcagccg agcttccagc tctaccatat cgttgttggc atagcgatag cgcttcgctt
    21601 tacacaaacg cacgccgtca atgatagacg cgtggttcag cgcgtcggaa ataatagcgt
    21661 cttccgcgcc cagcaacgtc tcaaacaagc cgccgttagc gtcgaaacag gaggaataca
    21721 gaatcgcatc ttccatgccg aggaagcttg ccagcttttg ctccagcgct ttgtggctgt
    21781 cctgggtgcc gcagataaaa cgcacggacg ccataccgaa accgtggctg tccatgcccg
    21841 cttttgcggc attaatcagc tcagggtgat tcgccagccc gagatagtta ttggcgcaaa
    21901 agttaataac gtggcttcca tccgccacgg tgatatccgc ctgctgcgca gacgtaataa
    21961 tgcgctcttc tttaaacaat ccttccgccc gggcggtttc cagatcgttg gttaactgtt
    22021 tgtaaaaatc cccacgcatt gcgattctcc agactgggca aatttcagca catattaccc
    22081 aaagctatac ggtgatacga gatgacgcgt catcacttct ttaaaatgca gcataaatca
    22141 cgcgtatcct cacgagttat cagtgaatgg atgaatagtg atatgataaa agcattcatg
    22201 tctgagacag tctctgacac cataattcaa aggttacagt tatgatcatc gttaccggcg
    22261 gcgcgggctt tatcggcagc aatatcgtta aggccctgaa tgataaaggt atcaccgata
    22321 ttctggtggt ggataacctg aaagacggca ccaagtttgt aaacctggtg gatctgaaca
    22381 ttgctgacta tatggataag gaagatttcc tgatccagat tatgtccgga gaagagctcg
    22441 gcgatatcga agctattttc catgaaggcg cctgctcttc caccaccgag tgggacggca
    22501 agtatatgat ggataataac tatcaatact ccaaagagct gctgcactat tgtcttgagc
    22561 gcgaaatccc gttcctctac gcctcttctg ccgccaccta tggcggtcgc acgtctgatt
    22621 tcatcgaatc gcgtgaatac gaaaaaccgc ttaacgttta cggctattct aaattcctgt
    22681 ttgatgaata cgtgcgccag atcctgccag aagcgaactc gcagattgtc ggtttccgct
    22741 atttcaacgt ctatggacca cgtgaaggcc ataaaggcag catggcaagc gtggcatttc
    22801 atctgaatac acagttaaac aacggcgaaa gtccgaaact gtttgaaggc agcgaaaact
    22861 tcaagcgcga cttcgtttac gtgggcgatg tggccgccgt taacctgtgg ttcctggaaa
    22921 gcggcaagtc cggcatcttt aacctgggca caggccgcgc ggaatctttc caggccgtcg
    22981 ccgacgcgac gctggcatac cataaaaaag gcagcattga atacattccg ttcccggata
    23041 agctgaaagg tcgctatcag gcgtttacgc aggcggattt aaccaatctg cgcaacgcgg
    23101 gctacgacaa accctttaag accgtcgccg aaggcgtcac ggagtatatg gcctggctga
    23161 accgcgacgc gtaagtatga aaattttggt cattggcccg tcctgggtgg gcgacatgat
    23221 gatgtcgcaa agtctctatc gcacgcttaa agcgcgctat ccccaggcga taatcgacgt
    23281 gatggcgcca gcctggtgcc gtccgttgtt atcgcgtatg ccggaagtta acgaggcgat
    23341 acccatgccg ctgggccacg gcgcgctgga aatcggcgag cgccgcagat tgggccatag
    23401 cctgcgagag aggcgctacg atcgcgcctg ggtgctgcca aattcgttta aatcggcgct
    23461 gattcctttc tttgccaata tcccgcaccg taccggctgg cgtggcgaaa tgcgctatgg
    23521 cctgctgaac gatgcgcgcg tccttgataa agacgcctgg ccgctgatgg tggagcgcta
    23581 cgtggcgctg gcctatgaca agggcgtgat gcgcacggcg aaagatctgc cgcagccgct
    23641 gctctggcca cagctccagg ttagcgaggg tgaaaaatcg ctgatgtaca gcgatttttc
    23701 gctatcttct gaacgtcctc taatcggctt ttgccccgga gcagaatttg gcccggcaaa
    23761 acgttggccg cactatcact acgccgaact ggcaaagcag ctcattaacg aagggtatca
    23821 ggtcgtgctg tttggctcgg caaaagacca tgaagccgga aatgagatcc tggcggcgct
    23881 gaatagcgag caacaggcat ggtgtcgcaa cctggcaggg gaaacccagc tggaacaggc
    23941 cgtcattctg atagccgcct gtaaagccat cgtcactaac gattccgggc tgatgcacgt
    24001 cgcggcggcg ctcgaccgcc cgctggtcgc gttgtatggc ccaagtagcc cggatttcac
    24061 gccgccgctg tctcataagg cccgggtgat tcgtctcatt acgggttacc acaaagtgcg
    24121 taaaggcgat acggcgcaag gctatcacca gagcctgatc gatatcacgc cgcagcgggt
    24181 tctggaagag cttcattcgc tgttgtcgga agagggcgtt taatgcgagt tttgatcgtt
    24241 aaaacatcat cgatgggcga cgtattacat accctgcctg cgcttaccga cgcgcaacag
    24301 gcgattccgg ggattcaatt tgattgggtt gtcgaagaag ggtttgcaca aattccgtcc
    24361 tggcacagtg ctgtcgatcg cgtgattccc gtcgctattc gccgttggcg caaggcctgg
    24421 ttttccgcgc ccattaaagc ggaacgcata gcctttcatc gggcggtatg cgcataccaa
    24481 tacgacgctg tgattgatgc gcaggggctg gtaaaaagcg cggcgctggt gacgcgtctg
    24541 gcgcatggga taaagcacgg tatggactgg agtaccgccc gcgaaccgct ggccagcctg
    24601 ttttataacc gtaaacacca tatcgcaaag caacaacatg cggttgaacg gacgcgcgag
    24661 ctgttcgcca aaagcctggg atacgataaa ccgcagtcgc agggcgatta tgccatcgca
    24721 aaacattttc tgcattgcca gcaggcggtt agcgatccgt atgcggtgtt tttacatgcc
    24781 acgacccgcg atgataaaca ctggccggaa gcaaactggc gcgagcttat cggcctggtg
    24841 ggcaacaccg gattacggat aaaacttccc tggggcgcgc ctcatgagga ggctcgtgct
    24901 aaacgactgg ccgaaggctt tgactatgtg gatgtgttac cgcgcatgag cctggaggag
    24961 gtcgctagag tgctggctgg cgcaaaattt gtcgtatcgg ttgataccgg cctgagccat
    25021 ctcaccgccg cgctcgacag accgaatatt acgctatatg gcccaacgga ccctgggtta
    25081 attggaggtt atgggaagaa ccaaatggca tgctgctcac cagaacaaaa cctggcgaat
    25141 ttagatgcca caagcgtatt tggaaagatt cattaaagag actctgtctc atcccaaacc
    25201 tattgtggag aaaagatgct aaccacatca ttaacgttaa ataaagagaa atggaagccg
    25261 atctggaata aagcgctggt ttttcttttt gttgccacgt attttctgga tggtattacg
    25321 cgttataaac atttgataat catacttatg gttatcaccg cgatttatca ggtctcacgc
    25381 tcaccgaaaa gtttcccccc tcttttcaaa aatagcgtat tttatagcgc agcagtatta
    25441 tcattaatcc ttgtttattc catactcata tcgccagata tgaaagaaag tttcaaagaa
    25501 tttgaaa
//
LOCUS       DAJVBX010000043        25398 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.043, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000043 DAJVBX010000000
VERSION     DAJVBX010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 25398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25398
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.043"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..1766
                     /locus_tag="OPV72_001554"
     CDS             <1..1766
                     /locus_tag="OPV72_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016159766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="aryl-sulfate sulfotransferase"
                     /protein_id="HCR9913899.1"
                     /translation="GAVALTCGLTAASTFAAGFQPAQPAGKLGAVVVDPYGNAPLTAL
                     VELDSHIISDVKVTVHGKGEKGVPVTYTVGKESLETYDGIPIFGLYQKFANNVTVEYK
                     ENGKAMKDDYVVQTSAIVNHYMDNRSISDLQQTKVIKVAPGFEDRLYLVNTHTFTPQG
                     AEFHWHGEKDKNAGILDAGPAGGALPFDIAPYTFVVDTQGEYRWWLDQDTFYNGHDMN
                     INKRGYLMGIRETPRGTFTAVQGQHWYEFDMMGQILADHKLPRGFLDASHESIETVNG
                     TVLLRVGKRDYRKEDGIHVHTIRDQIIEVDKSGRVVDVWDLTKILDPMRDALLGALDA
                     GAVCVNVDLAHAGQQAKLEPDTPYGDALGVGAGRNWAHVNSIAYDAKDDSIILSSRHQ
                     GIVKIGRDKQVKWILAPSKGWNKQLASKLLKPVDDHGKPLTCDENGKCKDTDFDFTYT
                     QHTAWLSSKGTLTVFDNGDGRGLEQPALPTMKYSRFVEYKIDEKKGTVQQVWEYGKER
                     GYDFYSPITSVVEYQKDRDTMFGFGGSINLFDVGKPTVGKLNEIDYKTKEVKVEIDVL
                     SDKPNQTHYRALLVHPTQMFK"
     gene            1786..2457
                     /locus_tag="OPV72_001555"
     CDS             1786..2457
                     /locus_tag="OPV72_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbA/DsbL"
                     /protein_id="HCR9913900.1"
                     /translation="MSSKWITSLFKSVVLTAALVTPFAASAFTEGTDYMVLEKPIPNA
                     DKTLIKVFSYACPFCYKYDKAVTGPVSDKVADLVTFTPFHLETKGEYGKQASEVFAVL
                     IAKDKAAGISLFDAKSQFKKAKFAWYTAYHDKKERWSDGKDPAAFIKTGLDAAGMSQA
                     DFEAALKDPAVQETLEKWKAAYDVAKIQGVPAYVVNGKYLIYTKNIKSIDSMAELVRE
                     LATKK"
     gene            2472..3149
                     /gene="dsbI"
                     /locus_tag="OPV72_001556"
     CDS             2472..3149
                     /gene="dsbI"
                     /locus_tag="OPV72_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-disulfide oxidoreductase DsbI"
                     /protein_id="HCR9913901.1"
                     /translation="MDFIKGLWRDLRARPVDTLVRWQEQRFLWLLMAIAMGGLIILAH
                     SFFQIYLYMAPCEQCVYIRYAMFVMVIGGVIAAINPKNIVLKLIGCIAAFYGSIMGIK
                     FSIKLNGIHHAVHNADPDSLFGVQGCSTDPTFPFNLPLAEWAPEWFKPTGDCGYDAPI
                     VPDGVTLSSVQQWFVDLYQQSEGWYLLPPWHFMNMAQACMLAFGLCLILLLVMSGAWA
                     LKLARGK"
     gene            complement(3320..3973)
                     /gene="ribB"
                     /locus_tag="OPV72_001557"
     CDS             complement(3320..3973)
                     /gene="ribB"
                     /locus_tag="OPV72_001557"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3,4-dihydroxy-2-butanone-4-phosphate synthase"
                     /protein_id="HCR9913902.1"
                     /translation="MNQTLLSSFGTPFERVELALDALREGRGVMVLDDEDRENEGDMI
                     FPAETMTVEQMALTIRHGSGIVCLCITEDRRKQLDLPMMVENNTSAYGTGFTVTIEAA
                     EGVTTGVSAADRVTTVRAAIKDGAKPSDLNRPGHVFPLRAQAGGVLTRGGHTEATIDL
                     MTLAGFKPAGVLCELTNDDGTMARAPECIAFAGQHNMAVVTIEDLVAYRQAHERKAS"
     regulatory      complement(4079..4277)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            4410..4706
                     /gene="ubiK"
                     /locus_tag="OPV72_001558"
     CDS             4410..4706
                     /gene="ubiK"
                     /locus_tag="OPV72_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone biosynthesis accessory factor UbiK"
                     /protein_id="HCR9913903.1"
                     /translation="MIDPKKIEQIARQVHESMPKGIREFGEDIEKKIRQTLQSQLTRL
                     DLVSREEFDVQTQVLLRTREKLALLEQRLSELEARDKPEEVKPAPAIPPVDPQE"
     gene            complement(4781..4990)
                     /gene="glgS"
                     /locus_tag="OPV72_001559"
     CDS             complement(4781..4990)
                     /gene="glgS"
                     /locus_tag="OPV72_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface composition regulator GlgS"
                     /protein_id="HCR9913904.1"
                     /translation="MLMNNNNVYSLNNFDFLARSFARMQAEGRPVDIQAVTGNMDEEH
                     RDWFCKRYALYCQQATQAKKLELEH"
     gene            5248..5868
                     /locus_tag="OPV72_001560"
     CDS             5248..5868
                     /locus_tag="OPV72_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1449 family protein"
                     /protein_id="HCR9913905.1"
                     /translation="MTLFAEYNSPYLFAIAFVFFIGVLEMISLIFGHFLSGALDAHLD
                     HYDALSSGPAGQALHYLNIGRVPALVVLCLLAGYFGLFGILIQHGGIMLWQAPLSNLL
                     LVPLSIVLSVFAVHYSEKILAPWLPRDESSALREEEFIGGMAIITGHAAVAGTPCEGK
                     FTDKFGQIHYLLLEPEKGKEFKKGDKVLIVCRLSATRYLAERTFYV"
     gene            5887..7566
                     /locus_tag="OPV72_001561"
     CDS             5887..7566
                     /locus_tag="OPV72_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HCR9913906.1"
                     /translation="MDDVFGILPSWMFTAIVAVIVLLIIGIIFARLYRRASAEQAFVR
                     TGLGGQKVVMSGGAIVMPIFHEIIPINMNTLKLEVSRATVDSLITKDRMRVDVVVAFF
                     VRVKPSVEGIATSAQTLGQRTLSPEDLRMLVEDKFVDALRATAAQMTMHELQDTRENF
                     VQGVQNTVAEDLSKNGLELESVSLTNFNQTSKEHFNPNNAFDAEGLTKLTQETERRRR
                     ERNEVEQDVEVAVREKNRDALERKLEIEQQEAFMTLEQEQQVKTRTAEQNAKIAAFEA
                     ERHREAEQTRILAERQIQETEIEREQAVRSRKVEAEREVRIKEIEQQQVTEIANQTKS
                     IAIAAKSEQQSQAEARANDALADAVRAQQNVETTRQTAEADRAKQVALIAAAQDAETK
                     AVELTVRAKAEKEAAELQAAAIIELAEAARKKGLAEAEAQRALNDAINVLSDEQTSLK
                     FKLALLQSLPAVIEKSVEPMKSIDGIKIIQVDGLNRGATAGDVAAGGANGGNLAEQAL
                     SAALTYRTQAPLIDSLLNEIGIAGGSLKALTTPLVSSATDEINREATIKEQ"
     gene            7807..7866
                     /locus_tag="OPV72_001562"
     CDS             7807..7866
                     /locus_tag="OPV72_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Ibs family toxin"
                     /protein_id="HCR9913907.1"
                     /translation="MMHQVIILIVLLLISFPAY"
     gene            complement(8026..9459)
                     /gene="hldE"
                     /locus_tag="OPV72_001563"
     CDS             complement(8026..9459)
                     /gene="hldE"
                     /locus_tag="OPV72_001563"
                     /EC_number="2.7.1.167"
                     /EC_number="2.7.7.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     D-glycero-beta-D-manno-heptose-7-phosphate
                     kinase/D-glycero-beta-D-manno-heptose 1-phosphate
                     adenylyltransferase HldE"
                     /protein_id="HCR9913908.1"
                     /translation="MKVNLPAFERAGVMVVGDVMLDRYWYGPTCRISPEAPVPVVKVN
                     TVEERPGGAANVAMNIASLGANARLVGLTGIDDAARALSKTLAEVNVKCDFVSVPTHP
                     TITKLRVLSRNQQLIRLDFEEGFEGVDPQPLHERINQALGSIGALVLSDYAKGALTSV
                     QTMISLARQAGVPVLIDPKGTDFERYRGATLLTPNLSEFEAVAGKCKSEDELVERGMK
                     LIADYDLSALLVTRSEQGMTLLQPNKAPLHMPTQAQEVYDVTGAGDTVIGVLAATLAA
                     GNTLEEACYFANAAAGVVVGKLGTSTVSPIELENAVRGRADTGFGVMTEEELRQAVAS
                     ARKRGEKVVMTNGVFDILHAGHVSYLANARKLGDRLIVAVNSDASTKRLKGESRPVNP
                     LEQRMIVLGALESVDWVVSFEEDTPQRLIAGILPDLLVKGGDYKPEEIAGSEEVWANG
                     GEVMVLNFEDGCSTTNIIKKIQTESEK"
     gene            complement(9507..12350)
                     /gene="glnE"
                     /locus_tag="OPV72_001564"
     CDS             complement(9507..12350)
                     /gene="glnE"
                     /locus_tag="OPV72_001564"
                     /EC_number="2.7.7.42"
                     /EC_number="2.7.7.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional [glutamate--ammonia
                     ligase]-adenylyl-L-tyrosine
                     phosphorylase/[glutamate--ammonia-ligase]
                     adenylyltransferase"
                     /protein_id="HCR9913909.1"
                     /translation="MTPLSSPLSQYWQTVVERLPEGFTETSLSAQAKSVLTFSDFALD
                     SVIAHPEWLAELESASPQADEWRHYAGWLQEALAGVCDDASLMRELRLFRRRIMVRIA
                     WAQTLSLVDDETILQQLSHLAETLIVGARDWLYAACCREWGTPCNPQGVPQPLLILGM
                     GKLGGGELNFSSDIDLIFAWPEHGETRGGRRELDNAQFFTRLGQRLIKALDQPTMDGF
                     VYRVDMRLRPFGDSGPLVLSFAALEDYYQEQGRDWERYAMVKARLMGDNDDAWSRELR
                     AMLRPFVFRRYIDFSVIQSLRNMKGMIAREVRRRGLKDNIKLGAGGIREIEFIVQVFQ
                     LIRGGREPSLQSRSLLPTLDAIAALHLLPENDVAQLRVAYLFLRRLENLLQSINDEQT
                     QTLPADDLNRARLAWGMKAENWPQLVGELTDHMANVRRVFNELIGDDEADTPQEEERS
                     EPWREVWQDALQEDDSTPVLAHLADEDRRQVLTLIADFRKELDKRPIGPRGRQVLDQL
                     MPHLLADVCSREDAAVTLSRITPLLAGIVTRTTYLELLSEFPGALKHLIMLCAASPMI
                     ASQLARYPLLLDELLDPGTLYQPTATDAYRDELRQYLLRVPEEDEEQQLEALRQFKQA
                     QLLRIAAADIAGTLPVMKVSDHLTWLAEAMIDAVVQQAWTQMVARYGQPAHLDERQGR
                     GFAVVGYGKLGGWELGYSSDLDLIFLHDCPMDVMTNGEREIDGRQFYLRLAQRIMHLF
                     STRTSSGILYEVDARLRPSGAAGMLVTSADAFADYQQHEAWTWEHQALVRARVVYGDP
                     QLTSQFDAVRRTIMTTARDGKTLQTEVREMREKMRAHLGNKHRDRFDIKADEGGITDI
                     EFIAQYLVLRYAHEKPKLTRWSDNVRILELLAQNGIMDEHEAQALTVAYTTLRDELHH
                     LALQELPGHVAQTCFSKERALVQASWRKWLVAV"
     gene            complement(12468..13769)
                     /locus_tag="OPV72_001565"
     CDS             complement(12468..13769)
                     /locus_tag="OPV72_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic triphosphatase"
                     /protein_id="HCR9913910.1"
                     /translation="MAQEIELKFIVNHDAVDALRNHLHTLGGEHHAPSQLLNIYFETP
                     DNWLRRHDMGLRIRGENGRYEMTMKIAGRVTGGLHQRPEYNVALSEPVLDLTQLPAEV
                     WPDGNLPDGLASSVQPLFSTDFYREKWCLDVDGSRIEIALDLGDVKAGEFAEPICELE
                     LELLRGDTRAVLKLAKQLLSQTGLRQGSLSKAARGYHLAQGNAPRENTPTAILRTAAK
                     ATVEQGLEASLDLALSQWQYHEELWLRGDESAKEHVLDAMGLVRHALMLFGGIVPRKA
                     SAHLRDLLTQAEATMTSAVSAVTAVYSTQTAMAKLALTEWLVTKAWQPFLDAKAQAKM
                     ADSFKRFADIHLSRHAAELKKVFGQPLGDKYRDQLPRLTRDIDSVLLLAGYYDAMVAQ
                     AWLENWQGLRHAIITGQRIEIEHFRNEAINQQPFWLHSGKR"
     gene            14011..14625
                     /locus_tag="OPV72_001566"
     CDS             14011..14625
                     /locus_tag="OPV72_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HCR9913911.1"
                     /translation="MPKLRLIGLTLLALSATAVSHAEETRYVSDELNTWVRSGPGDNY
                     RLVGTVNAGEEVTLLQSDANYGQIKDSSGRTAWIPLKELNTTPSLRTRVPDLENQVKT
                     LTDKLNNIDTTWNQRTADMQQKVAQSDSVINGLKEENQKLKNELIVAQKKVSAANLQL
                     DDKQRTIIMQWFMYGGGVLGIGLLLGLVLPHMIPSRKRKDRWMN"
     gene            14688..15929
                     /locus_tag="OPV72_001567"
     CDS             14688..15929
                     /locus_tag="OPV72_001567"
                     /EC_number="2.7.7.72"
                     /EC_number="3.1.3.-"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multifunctional CCA addition/repair protein"
                     /protein_id="HCR9913912.1"
                     /translation="MKIYLVGGAVRDALLGLPVKDKDWVVVGATPQEMLDAGYQQVGR
                     DFPVFLHPQTHEEYALARTERKSGSGYTGFTCYAAPDVTLEADLQRRDLTINALARDD
                     DGQIIDPYHGRRDLEARLLRHVSPAFGEDPLRVLRVARFAARYAHLSFRIADETLTLM
                     REMTAAGELEHLTPERVWKETENALTTRNPQVYFQVLRDCGALRVLFPEIDALFGVPA
                     PAKWHPEIDTGVHTLMTLSMAAMLSPQLDVRFATLCHDVGKGLTPKNLWPRHHGHGPV
                     GVKLVEQLCQRLRVPNDLRDLAKLVAAYHDLIHTFPILQPKTIVKLFDAIDAWRKPQR
                     VEQIALTSEADVRGRTGFEASDYPQGRWLREAWQVAQAVPTKEVVEAGFKGIEIREEL
                     TKRRIAAVANWKEKRCPNPAS"
     gene            complement(16034..16855)
                     /gene="bacA"
                     /locus_tag="OPV72_001568"
     CDS             complement(16034..16855)
                     /gene="bacA"
                     /locus_tag="OPV72_001568"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HCR9913913.1"
                     /translation="MSDMHSLLIAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDT
                     AKTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRPLQREGESKGRLTLIHILLGMIPA
                     VVLGLVFHDTIKSLFNPINVMYALVVGGLLLIAAECLKPKEPRAPGLDDMTYRQAFMI
                     GCFQCLALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATVLDLYKSWSF
                     LTAADIPMFAVGFVTAFVVALIAIKTFLQLIKRISFIPFAIYRFVVAAAVYVVFF"
     gene            complement(16953..17312)
                     /gene="folB"
                     /locus_tag="OPV72_001569"
     CDS             complement(16953..17312)
                     /gene="folB"
                     /locus_tag="OPV72_001569"
                     /EC_number="4.1.2.25"
                     /EC_number="5.1.99.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708868.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional dihydroneopterin
                     aldolase/7,8-dihydroneopterin epimerase"
                     /protein_id="HCR9913914.1"
                     /translation="MDIVFIEQLSVITTIGVYDWEQTIEQKLVFDIEMAWDNRKSAKS
                     DDVADCLSYADIADTVINHVEGGRFALVERVAEEVADLLLSRFNSPWVRIKLSKPSAV
                     ARAANVGVIIERGNNLK"
     gene            17419..18030
                     /gene="plsY"
                     /locus_tag="OPV72_001570"
     CDS             17419..18030
                     /gene="plsY"
                     /locus_tag="OPV72_001570"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HCR9913915.1"
                     /translation="MSAIAPGMILFAYLCGSISSAILVCRIAGLPDPRESGSGNPGAT
                     NVLRIGGKGAAVAVLIFDILKGMLPVWGAYALGVTPFWLGLIAIAACLGHIWPVFFGF
                     KGGKGVATAFGAIAPIGWDLTGVMAGTWLLTVLLSGYSSLGAIVSALIAPFYVWWFKP
                     QFTFPVSMLSCLILLRHHDNIQRLWRRQETKIWTKLKKKRQKD"
     gene            18029..18157
                     /locus_tag="OPV72_001571"
                     /pseudo
     CDS             18029..18157
                     /locus_tag="OPV72_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311971.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase"
     gene            18159..18239
                     /locus_tag="OPV72_001572"
                     /pseudo
     CDS             18159..18239
                     /locus_tag="OPV72_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311973.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:sulfate symporter"
     gene            complement(18280..19293)
                     /gene="tsaD"
                     /locus_tag="OPV72_001573"
     CDS             complement(18280..19293)
                     /gene="tsaD"
                     /locus_tag="OPV72_001573"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001264383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HCR9913916.1"
                     /translation="MRVLGIETSCDETGIAIYDDKKGLLANQLYSQVKLHADYGGVVP
                     ELASRDHVRKTVPLIQAALKEAALTASDIDAVAYTAGPGLVGALLVGATVGRSLAFAW
                     NVPAIPVHHMEGHLLAPMLEDNPPDFPFVALLVSGGHTQLISVTGIGQYELLGESIDD
                     AAGEAFDKTAKLLGLDYPGGPMLSKMASQGTAGRFVFPRPMTDRPGLDFSFSGLKTFA
                     ANTIRSNGDDEQTRADIARAFEDAVVDTLMIKCKRALESTGFKRLVMAGGVSANRTLR
                     AKLAEMMQKRRGEVFYARPEFCTDNGAMIAYAGMVRFKAGVTADLGVTVRPRWPLAEL
                     PAA"
     gene            19521..19736
                     /gene="rpsU"
                     /locus_tag="OPV72_001574"
     CDS             19521..19736
                     /gene="rpsU"
                     /locus_tag="OPV72_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HCR9913917.1"
                     /translation="MPVIKVRENEPFDVALRRFKRSCEKAGVLAEVRRREFYEKPTTE
                     RKRAKASAVKRHAKKLARENARRTRLY"
     gene            19972..21717
                     /gene="dnaG"
                     /locus_tag="OPV72_001575"
     CDS             19972..21717
                     /gene="dnaG"
                     /locus_tag="OPV72_001575"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HCR9913918.1"
                     /translation="MAGRIPRVFINDLLARTDIVDLIDVRVKLKKQGKNYHACCPFHN
                     EKTPSFTVNGEKQFYHCFGCGAHGNAIDFLMNYDKLEFVETVEELAAMHNLEIPYEAG
                     TGLSQIERHQRQNLYQLMNGLNDFYQQSLTHPAAKPARDYLQKRGLSAEIIQRFAIGF
                     APPGWDNALKRFGNNSDNKALLLDAGMLVNNEQGSTYDRFRNRVMFPIRDKRGRVIGF
                     GGRVLGNDTPKYLNSPETDIFHKGRQLYGLYEAQQYSAEPQRLLVVEGYMDVVALAQY
                     DINYAVASLGTSTTADHMHMLFRATNNVICCYDGDRAGRDAAWRALETAMPYMTDGRQ
                     VRFMFLPDGEDPDTLVRKEGKAAFEARMEQAQPLSTFLFNSLLPQVDLSSPDGSTQLA
                     ALALPLINQVPGDTHRIQLRQTLGLKLGIFDDSQLDRLVPKQAESGVSRPAPQLKRTT
                     MRILIGLLVQNPDLAPLVPPLDALDQNKLPGLGLFKELVKTCLAQPGLTTGQLLELYR
                     GTNDAATLEKLSMWDDIADKAIAEKTFTDSLNHMFDSLLQLRQEELIARDRTHGLSSE
                     ERRELWTLNQELARK"
     gene            21867..23714
                     /gene="rpoD"
                     /locus_tag="OPV72_001576"
     CDS             21867..23714
                     /gene="rpoD"
                     /locus_tag="OPV72_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HCR9913919.1"
                     /translation="MEQNPQSQLKLLVTRGKEQGYLTYAEVNDHLPEDIVDSDQIEDI
                     IQMINDMGIQVMEEAPDADDLLLAENTTSTDEDAEEAAAQVLSSVESEIGRTTDPVRM
                     YMREMGTVELLTREGEIDIAKRIEDGINQVQCSVAEYPEAITYLLEQYDRVEAEEARL
                     SDLITGFVDPNAEEEMAPTATHVGSELSQEDLDDDEDEDEEDGDDDAADDDNSIDPEL
                     AREKFAELRAQYVVTRDTIKAKGRSHAAAQEEILKLSEVFKQFRLVPKQFDYLVNSMR
                     VMMDRVRTQERLIMKLCVEQCKMPKKNFITLFTGNETSETWFNAAIAMNKPWSEKLHD
                     VAEEVQRCLQKLRQIEEETGLTIEQVKDINRRMSIGEAKARRAKKEMVEANLRLVISI
                     AKKYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQAR
                     TIRIPVHMIETINKLNRISRQMLQEMGREPTPEELAERMLMPEDKIRKVLKIAKEPIS
                     METPIGDDEDSHLGDFIEDTTLELPLDSATTESLRAATHDVLAGLTAREAKVLRMRFG
                     IDMNTDHTLEEVGKQFDVTRERIRQIEAKALRKLRHPSRSEVLRSFLDD"
     gene            complement(23838..24344)
                     /gene="mug"
                     /locus_tag="OPV72_001577"
     CDS             complement(23838..24344)
                     /gene="mug"
                     /locus_tag="OPV72_001577"
                     /EC_number="3.2.2.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G/U mismatch-specific DNA glycosylase"
                     /protein_id="HCR9913920.1"
                     /translation="MVKDILAPGLRVVFCGINPGLSSANTGFPFAHPANRFWKVIHLA
                     GFTDRQLKPEEAEKLLDFRCGVTKLVDRPTVQATEVKLHELRSGGRNLIEKIEDYQPA
                     ALAVLGKQAFEQGFSQRGIAWGKQKIAIGATMVWVLPNPSGLNRIKTEKLVEAYRELD
                     QALIMRGL"
     gene            24470..24545
                     /locus_tag="OPV72_001578"
     tRNA            24470..24545
                     /locus_tag="OPV72_001578"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:24503..24505,aa:Ile,seq:cat)
     gene            complement(24625..25392)
                     /locus_tag="OPV72_001579"
     CDS             complement(24625..25392)
                     /locus_tag="OPV72_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore-interacting protein"
                     /protein_id="HCR9913921.1"
                     /translation="MTTSSARYPQRVRNELRFRELTVLRVERISAGFQRIVLGGEALD
                     GFTSLGFDDHTKVFFPEPGCRFTPPTVTEEGIIWGEGVRPVSRDYTPLYDEAHRELAL
                     DFFIHDGGVASRWAMEAREGDTLTIGGPRGSLVVPEDYACQVYVCDESGMPALRRRLE
                     SLSRLPARPAVTALVSIQDAAYRDYLAHLTDITVEYVVGGDEQAMQTRLSQLAIPESD
                     YFIWITGEGKTVKRLSQCFEKGFDPHLVRAAAYWHRK"
BASE COUNT         6218 a         7012 c         6497 g         5671 t
ORIGIN      
        1 ccggcgccgt cgcactgaca tgcggactca ccgcagccag tacgtttgcc gcaggttttc
       61 aaccggcgca gcccgcaggg aaattaggcg cagtcgttgt cgatccttac ggtaatgccc
      121 ctctcaccgc actggtggaa ttagatagcc atattatttc agacgttaaa gttactgtac
      181 atggcaaagg ggaaaaaggc gttcccgtta cttataccgt tgggaaagag tctttagaaa
      241 cctatgacgg tattcctatt tttggccttt atcagaaatt tgccaacaac gtcacggtag
      301 aatataaaga aaacggcaaa gccatgaagg atgactatgt ggtgcagacg tccgccatcg
      361 tcaaccatta tatggataac cgttctattt cagatctcca gcaaacgaaa gttattaaag
      421 ttgcgccagg atttgaagat cgcctttatc tggtaaatac ccataccttt acgccgcagg
      481 gcgctgaatt tcactggcac ggcgaaaaag ataaaaatgc gggcattctt gatgccggcc
      541 cggcgggcgg ggctttgcct ttcgatatcg ccccttatac gtttgtggtc gacacccagg
      601 gtgaataccg ctggtggctg gatcaagata ccttctacaa cggccacgat atgaatatca
      661 acaaacgtgg ctacctgatg gggattcgtg aaacgcctcg cggcaccttt accgcggtgc
      721 agggccaaca ctggtacgag tttgacatga tggggcaaat tcttgccgat cataaactgc
      781 cgcgcgggtt cctggacgca tctcatgaat ccatcgaaac cgtgaacggt accgtactgc
      841 tgcgcgtcgg caaacgcgat taccgcaaag aagacggcat acatgttcat actattcgtg
      901 accaaatcat tgaggttgat aagtctggcc gcgtagtaga cgtttgggat ttaaccaaaa
      961 tcctcgaccc tatgcgtgat gcgctgctcg gcgcgctgga tgcgggcgca gtatgcgtga
     1021 acgtcgatct ggcccatgcc ggacagcagg cgaaactcga accggatacg ccgtatggcg
     1081 atgcgcttgg cgttggtgcc ggtcgtaact gggcgcacgt caactctatc gcttatgacg
     1141 cgaaagacga ctccatcatc ctttcttccc gccatcaggg tattgtaaaa attggtcgcg
     1201 ataagcaggt gaaatggata ctggcaccgt ctaaaggctg gaataagcag ctagccagta
     1261 aattgctgaa accggtagac gatcatggta agccgttgac ctgtgacgaa aacggcaagt
     1321 gtaaggacac cgatttcgat ttcacctata cccaacatac ggcatggctt tccagcaaag
     1381 gtacgttaac ggtctttgat aacggtgatg gtcgcggcct ggagcaaccg gctctaccga
     1441 ccatgaaata ttcccgtttt gtcgaatata agatcgatga gaagaaaggc accgtacaac
     1501 aagtttggga atacggtaaa gaacgtggat atgatttcta tagtcctatt acctcggttg
     1561 ttgaatatca aaaagaccgc gacaccatgt tcggctttgg cggttctatt aacctgttcg
     1621 acgttggtaa accaacagtc ggcaaactga atgagattga ctataaaacg aaagaagtga
     1681 aagttgaaat tgatgtgctg tcggataaac ccaaccagac tcactatcgt gcgttactgg
     1741 tacatccaac acaaatgttt aaataaatca cgggaaggaa ttaatatgtc atctaaatgg
     1801 attacctctt tatttaaaag cgtagtatta accgcggcat tggtcactcc ttttgcggca
     1861 tcggctttta ccgagggcac agattatatg gttctggaga aaccaattcc taatgcggat
     1921 aaaacgctga ttaaggtatt tagctacgcc tgccctttct gctacaaata tgacaaagcc
     1981 gtaacaggtc cggtttctga taaagtcgcc gatctcgtta cgttcacccc gttccacctg
     2041 gaaacaaaag gcgaatatgg caaacaggcc agcgaagtat ttgcagtcct gatcgccaaa
     2101 gataaagctg ccgggatttc gttatttgat gctaaatcac aattcaaaaa agcgaagttc
     2161 gcctggtata cggcttacca tgataagaaa gagcgctggt cagatgggaa agatccggcg
     2221 gcatttatta aaaccgggct ggacgccgca ggcatgagcc aggctgattt tgaagcggcg
     2281 ctgaaagatc ctgccgttca ggagactctg gaaaaatgga aagcagccta tgacgttgcc
     2341 aaaattcagg gtgttccggc ttacgtcgtc aacggcaagt accttatcta caccaaaaac
     2401 atcaaatcca tcgattctat ggctgaactc gttcgggaac tggccactaa aaaataagca
     2461 gggaaacgat tatggatttt attaagggat tatggcgaga cctacgcgca agaccagtgg
     2521 atacgctggt gagatggcag gaacagcgct ttctgtggct gttaatggcc atcgcgatgg
     2581 gaggattaat tatcctggcg cactcgttct tccaaatcta cctctacatg gcaccgtgcg
     2641 agcagtgtgt ttacatccgt tacgcgatgt ttgtgatggt aattggcggg gtgattgcgg
     2701 caataaatcc caaaaatatt gtgctgaagc tgattggctg catcgcggcg ttttatggca
     2761 gcattatggg cattaagttt tctattaagc ttaatggtat ccatcatgcg gtacataatg
     2821 cggaccccga ttcacttttt ggcgtgcaag gatgttcgac tgacccgacc tttcctttca
     2881 acttaccgtt ggcggaatgg gcaccggagt ggtttaaacc taccggagac tgcggttatg
     2941 acgcgcctat cgtccctgat ggcgtgacgc tcagtagcgt acagcagtgg tttgtcgatc
     3001 tctaccagca gtccgaaggc tggtatctgc ttccgccctg gcactttatg aacatggcgc
     3061 aggcatgtat gttggccttt gggttgtgcc tgattctgct gctggtgatg agcggcgcct
     3121 gggcattgaa actggccaga ggcaaataac ctgaatagat aaaccaaagc agaggtctgc
     3181 attcaggcct ctgcttttct cacaataatt ttaccattca gcttattcgt cgttctttga
     3241 aactgaacaa tatggcaccg aaggaataca aaaaagccga tgagatgtca tcggcttttt
     3301 tcaaccatga tccgttcgat cagctggctt tgcgctcatg cgcctggcgg taagccacca
     3361 gatcttcaat cgtgaccacc gccatattat gctggcctgc aaacgcgata cactccggcg
     3421 cgcgcgccat cgtcccatcg tcgttagtca actcgcacag tacacctgca ggtttaaaac
     3481 cggccagcgt catcagatcg atggtcgcct ccgtatgacc gccgcgcgtc agcacgccgc
     3541 ccgcctgagc gcgcagtggg aaaacgtgcc ccggacggtt aagatcggac ggttttgcgc
     3601 catccttaat tgccgcacgc accgtagtga cacggtcagc ggcggaaacg ccggtggtca
     3661 cgccttctgc ggcttcaatg gtcacggtaa aaccggtgcc gtaggcgctg gtgttgtttt
     3721 ccaccatcat tggcaaatcg agctgcttac ggcgatcttc agtaatacac aggcaaacaa
     3781 taccgctacc gtgacgaatg gttaacgcca tctgttctac ggtcattgtc tctgcgggga
     3841 aaatcatatc gccttcgttt tcacgatctt catcatcaag caccatcaca ccgcgtcctt
     3901 cacgcagcgc atccagtgca agttcaacac gttcaaaagg cgtaccaaaa gaggaaagta
     3961 gcgtctgatt catggtaaaa aaacctcatt aacattatgg ttaccagaat cagggcagtc
     4021 ttaggagtgc cgacaagcgg caaaaaaata acgtgagcgg gtccatgccc gactggatcg
     4081 ttaccctctc ccatccggac tttaaccgtc ggccccggaa ttacaccgga tctgctgacc
     4141 ttttcgctat ggcaaaaagc gctcgcgggc tttcaacctg ctctccgcgt tccgtcacgg
     4201 cgcaccgtga tgagaaatgc gttaaacatc gctgatttac cgccggtggg gaatttcgcc
     4261 ccgccctgag aataagcggg ttaactataa cgctattgat taccttcatc aacgccttta
     4321 ctccgtatga catcacacaa ttctggttta tggcgtccac atatcgcact acaataagag
     4381 ctaacactta ccagttcagg gaaaccacaa tgattgaccc gaaaaaaatt gagcaaatcg
     4441 cacgccaggt tcatgagtca atgccgaaag gtattcgcga gttcggggaa gatatcgaga
     4501 aaaaaatccg tcaaacgctg caatctcagc tgacgcgtct cgatctggtg agccgcgaag
     4561 agtttgatgt ccagactcag gtcttgctgc gcacccggga aaaactggcg ctgctggagc
     4621 aacgcctcag cgaactggaa gctcgcgaca agcctgaaga agtaaaacct gcgcccgcca
     4681 ttccgccagt cgatccacaa gagtaaaaac gtgaacgggc ctgacggccc gctcatataa
     4741 gatctgaata atgccctgcg cctgtataag ggagcctgca ttagtgttct aattctaact
     4801 ttttcgcctg agtcgcctgc tggcagtaaa gcgcgtaacg cttgcaaaac cagtcgcggt
     4861 gctcctcgtc catattgccg gttaccgcct ggatatcaac aggacgcccc tccgcctgca
     4921 ttctggcaaa gctgcgcgcc agaaaatcga aattatttaa tgaatagacg ttattgttgt
     4981 tcatcagcat accctccagt tattgaattc tgttaaggct atatgctttt tctaatttca
     5041 gtatttccct atatgtacgg cggttttata cataacgtgc gcaaatttaa tgcgcaaaat
     5101 cacaatattc accaaagata acgacggata aatcgctttt cggacttaag gagatatggg
     5161 tcacatgata ttgtaacgca atgaaataac aagcatgaaa attatcacgc gaacatcctt
     5221 ctgaaggcgg cgacaaggat agaaaatatg accttatttg cggagtataa cagcccctat
     5281 ctgtttgcca tcgcgttcgt tttctttatc ggcgtgctgg agatgatttc tctgattttt
     5341 ggccactttc tttcaggcgc gctcgacgcc catctcgatc attatgatgc cctgtcatcc
     5401 ggccctgcgg gccaggcgct tcattatctg aatattggac gcgttcccgc cctagtcgtc
     5461 ctctgtctat tggccggcta tttcggcctc ttcggtatcc tcatccagca tggcgggatc
     5521 atgctctggc aggcgccgct cagcaatctg ctgctggtcc cgttaagcat tgtcctgtcg
     5581 gtctttgccg tgcattacag cgaaaaaatc ctcgcgccct ggctacccag agatgaaagc
     5641 tccgccctcc gggaagagga atttatcggc ggcatggcga ttattaccgg ccacgccgcc
     5701 gtcgccggaa caccttgcga aggaaaattt accgataagt tcggccagat tcactattta
     5761 ctgctggaac ccgaaaaggg aaaagaattt aaaaaaggag acaaggtgct gattgtctgc
     5821 cgactttccg caacgcgtta tttggctgag cgtaccttct atgtttaatt gagaggaact
     5881 tacataatgg atgatgtttt tggcatattg ccatcatgga tgtttaccgc catcgtggcg
     5941 gttatcgtct tactaattat cgggatcatt tttgctcgcc tttatcgccg cgcatctgcg
     6001 gaacaggcgt ttgtccgtac cgggcttggc gggcaaaaag tggtgatgag cggcggcgct
     6061 attgtgatgc caatctttca cgaaattatt ccgatcaata tgaataccct aaaacttgaa
     6121 gtcagccgtg ctaccgtcga cagcctgatc accaaagatc gtatgcgcgt tgacgtggtc
     6181 gttgctttct tcgtgcgtgt aaaaccctct gttgaaggta ttgccacctc cgcacaaacg
     6241 cttggccagc gaacgctgtc accggaagat ctgcgtatgc tggttgagga taaattcgtt
     6301 gacgccttac gcgctaccgc agcccagatg acgatgcatg agctacagga tacgcgtgaa
     6361 aacttcgttc agggcgtaca aaacaccgtt gcggaagatt tgtcgaaaaa cggcctggag
     6421 ctggaaagcg tctcattaac caactttaac caaacgtcca aagagcattt caatccaaac
     6481 aatgcctttg atgccgaagg tctgacgaaa ctgacgcagg aaaccgaacg ccgccgtcgt
     6541 gaacgtaatg aagtggaaca ggatgtggaa gtggcggtgc gcgaaaagaa ccgcgacgcg
     6601 cttgaacgca agctggaaat cgagcaacaa gaagccttta tgactctgga gcaggagcaa
     6661 caggttaaaa cccgcaccgc cgaacaaaac gccaaaattg ccgcttttga ggccgagcgc
     6721 catcgtgaag cagaacagac gcgcattctt gctgagcggc agatccagga gacggagatc
     6781 gaacgtgagc aagcagtacg gtccaggaaa gttgaggccg agcgtgaagt acgtattaaa
     6841 gagatcgaac agcaacaggt gacagaaatc gccaaccaga cgaaatctat cgccattgcc
     6901 gccaaatccg agcagcaatc gcaagcggaa gcgcgcgcca acgacgcgct ggccgatgcg
     6961 gttcgcgccc agcaaaacgt agaaaccacc cgccagaccg ccgaagcgga tcgcgccaag
     7021 caggtcgctc tgatcgccgc ggcgcaggat gcggaaacca aagcggtcga actgaccgtt
     7081 cgggcaaaag cagagaaaga agcggcagaa ttgcaagccg ccgccatcat cgaactggcg
     7141 gaagcagcgc gtaaaaaagg tctggcggaa gccgaagcgc aacgggcgct gaatgacgct
     7201 atcaacgtac tatctgacga acaaaccagc ctcaaattta aactagcgct cttacaatcg
     7261 ttgcctgctg ttattgagaa gtctgttgaa ccgatgaaat ccatcgacgg cattaagatt
     7321 attcaggtcg atggcctcaa tcgcggcgcg acggcgggcg acgtcgccgc tggcggcgct
     7381 aacgggggaa acctggcgga acaagcgtta tctgccgcgc tcacctatcg tacccaggcg
     7441 ccgctgatcg attcgctgtt aaacgagatt ggcatcgccg gcggctcgct aaaggcgctg
     7501 accacgccgt tggtttcatc ggcaacggat gagattaatc gcgaagcaac gataaaagag
     7561 caataacctc cccgccatat ctcctgtccc tggccataag gccggggatt tttttatctt
     7621 ttttccacct tgtctgtaca aagcgttatg accagcaggc cattttgcgt gggcgatcca
     7681 gtaacgcaaa atcggcggga gaaagccctt gcgccagaca ggccactcac caacaatcgc
     7741 gatgtcagca aggggctgaa acgggaaagc ccctcccgag gaaggggctt taataaggaa
     7801 agggttatga tgcaccaggt catcatactg attgttctgt tactgataag tttcccagct
     7861 tactaacagc caatcagagg ggggagagat cccctctcac ccttattcct ttactttagg
     7921 tcgaaaaaaa agcagcgtca accgcgagat acgcgtcgaa acaaaatgtc cgacgcacct
     7981 tcaaaatcag cgcccgcagc gtctgtaacg cctgatgacg cggttttact tctcgctctc
     8041 ggtctggatc tttttgatga tattggtcgt ggaacaacca tcttcgaagt tcagcaccat
     8101 gacttcgccg ccgttggccc agacctcttc gctgcccgcg atctcttccg gcttatagtc
     8161 gccgcctttt accagcagat ccggcagaat accggcaatc agtcgttgcg gcgtatcctc
     8221 ttcaaaagag acaacccagt cgaccgactc cagcgcgccc agcacgatca tacgctgttc
     8281 gagcggatta accggacggc tttcgccttt cagacgttta gtcgaggcgt cactattgac
     8341 cgcaacaatc aggcggtcgc ccagtttgcg cgcgttcgcc agataagaga cgtggcccgc
     8401 gtgcagaata tcgaaaacgc cgttggtcat gaccactttc tcgccacgct tacgcgcgct
     8461 ggcgacggcc tgtctcaact cctcttcggt catgacgccg aagccggtat ccgcgcgtcc
     8521 gcgcactgcg ttttccagct caatagggga aaccgttgac gtcccgagtt tacctaccac
     8581 tacgcccgcc gccgcattgg cgaaataaca cgcctcctcc agggtatttc ccgccgccag
     8641 cgtcgccgcc agcacgccga tcaccgtatc gcccgcaccg gtaacatcat aaacttcctg
     8701 cgcctgcgtc ggcatatgta gcggcgcttt attcggttgc agcagcgtca ttccctgttc
     8761 ggaacgcgtg accaacagcg cggaaaggtc gtaatcggca atgagcttca tgccgcgttc
     8821 aaccagttcg tcttcgcttt tacatttccc cgcaaccgcc tcgaattcag aaaggtttgg
     8881 cgtcagcagc gtggcgccgc ggtaacgttc aaaatccgtt cctttcggat cgatgagcac
     8941 cggcacgccc gcctggcgcg ctagggaaat catagtctgc acgctggtca gagcgccttt
     9001 ggcataatcg gacaatacca gcgcgccgat cgatcccagc gcctggttga tacgctcatg
     9061 caacggctgc gggtccacgc cctcaaagcc ttcttcaaaa tcaagacgaa tgagctgctg
     9121 attacgtgat agtacgcgca gtttggtaat cgtcggatgc gtcggcacag aaacgaagtc
     9181 gcacttcaca ttgacctccg ccagcgtttt gctcagcgcg cgcgcggcgt catcaatacc
     9241 cgtcaggccg accagacggg cgttcgctcc cagagacgca atgttcatcg ccacgttcgc
     9301 cgcgccgccc ggacgttcct caacggtatt taccttaacc acgggcaccg gcgcttccgg
     9361 tgaaatacgg caagtggggc cataccaata gcgatccagc attacatcac ccacaaccat
     9421 gacgcctgca cgttcaaacg ctggcagatt tactttcatt cctgtctcct gagagattca
     9481 aaatttgcgc gcgataatag cataattcaa acggctacca gccacttccg ccagcttgcc
     9541 tgcaccagcg cgcgctcttt gctaaaacat gtctgcgcca catgaccggg aagctcctgc
     9601 aacgccaggt ggtgcagttc atcacgcagt gtggtgtagg ctaccgtcag cgcctgcgct
     9661 tcgtgttcat ccataatgcc gttttgcgcc agaagctcca ggatgcgcac gttatcagac
     9721 cagcgcgtta atttaggttt ttcatgagcg tagcgcagta ccagatattg cgcgataaac
     9781 tcaatatccg taataccgcc ttcatcagct ttaatatcaa aacgatcgcg atgcttattg
     9841 ccgagatgcg cccgcatttt ctcgcgcatt tcacgcactt cagtctgcaa tgtcttaccg
     9901 tcacgcgccg tcgtcatgat agtgcggcgc accgcatcaa actgtgaggt aagctgcggg
     9961 tcgccatata ccacgcgagc gcgtaccaac gcctgatgtt cccaggtcca ggcttcatgc
    10021 tgctgataat cggcaaacgc gtccgctgaa gtcaccagca ttccagccgc gccagagggg
    10081 cgtagacgcg catccacctc atacaaaatg ccggaggagg tgcgcgtact gaacagatgc
    10141 ataatgcgct gcgccaggcg cagataaaac tgccgcccgt cgatttcgcg ttcgccgttg
    10201 gtcatgacgt ccatcggaca gtcatgcagg aagatgagat ccagatcgga actgtagccc
    10261 agctcccatc cgcccaactt gccataaccg acgaccgcaa acccccgccc ctggcgttcg
    10321 tccagatgcg ctggctgacc ataacgcgca accatttgcg tccacgcctg ctgcaccaca
    10381 gcatcaatca tcgcctccgc cagccatgtg aggtgatcgc tcactttcat caccggcagc
    10441 gtaccggcaa tatccgccgc cgcaatccgc aaaagctgtg cctgtttaaa ctggcgtaat
    10501 gcctccagtt gttgttcttc gtcctcttcc ggcacgcgca gcaaatactg gcgtaattcg
    10561 tcgcggtaag cgtcggtagc cgtcggctga taaagcgtgc cggggtcgag cagttcatca
    10621 agcaacaacg gataacgcgc cagttggctc gctatcattg gcgaagcggc gcagagcata
    10681 atcaggtgtt tcagcgcgcc gggaaattcg ctcagcagct ccagataggt ggtgcgagtg
    10741 acaatccccg ccagcaacgg cgttatccgc gatagcgtaa cagcggcgtc ttcgcgggaa
    10801 cagacgtcag caagcaggtg cggcatcagt tggtccagca cctgccgccc gcgcgggccg
    10861 atagggcgtt tatccagttc cttacggaag tcagcgataa gggtcagaac ctgtcgccga
    10921 tcctcatcgg ctaaatgcgc cagcactggc gtcgaatcat cctcctgtag cgcatcctgc
    10981 catacttcac gccacggctc tgaacgttct tcctcctgcg gggtatcggc ttcatcatcg
    11041 ccaattaatt cgttgaatac gcggcgtaca ttagccatat gatccgtcag ttcgccaaca
    11101 agctgcggcc agttctccgc cttcattccc caggccagcc gcgcccgatt cagatcgtcg
    11161 gcaggcaacg tttgcgtctg ttcgtcattg atgctttgca gcagattctc cagacgacgt
    11221 agaaaaagat aggccacgcg tagttgcgcc acgtcattct caggcagcaa atgcagcgca
    11281 gcgatagcat ccagcgtcgg cagtaacgaa cgcgactgta gcgacggctc gcgtccgccg
    11341 cggatcagct ggaatacctg cacgataaac tcaatttccc gaataccgcc cgcgccaagt
    11401 ttaatgttgt ctttcaaacc gcggcgtcgc acttcgcggg cgatcatccc tttcatatta
    11461 cgtagcgact ggatgacgct gaaatcgata tagcggcgga aaacgaaagg ccgcagcatg
    11521 gcgcgtaatt cacgagacca ggcgtcgtcg ttatcgccca ttagccgcgc tttcaccatg
    11581 gcgtagcgtt cccagtcgcg tccttgctcc tgatagtaat cctccagcgc ggcaaaactc
    11641 agtaccagcg ggccgctgtc gccaaacggt cgcaggcgca tgtctacccg atagacaaaa
    11701 ccatccattg tgggctgatc cagcgctttg atcagccgct gcccgagacg cgtaaaaaac
    11761 tgggcgttat cgagttcacg acgcccgccc cgggtctcgc catgttccgg ccaggcgaaa
    11821 atcagatcga tatcagacga aaaattcagt tcgccgccgc ccagcttgcc catgcctaaa
    11881 atcagcagcg gctgcggaac gccctgcggg ttacaggggg ttccccattc gcggcaacag
    11941 gcggcataca gccagtcgcg cgccccgacg atgagcgtct ccgccagatg gctcaactgt
    12001 tgtaaaatag tctcatcgtc caccagcgac agcgtctgtg cccaggcgat gcgtaccatg
    12061 atgcgacgac gaaaaagcct cagctcacgc atcagcgagg cgtcgtcaca gacacctgcc
    12121 aacgcctcct gtaaccagcc agcgtaatgt cgccattcat cagcctgcgg cgatgcggat
    12181 tccagttcgg caagccactc cggatgcgct atcacgctat ccagcgcaaa atcgctaaat
    12241 gtaagcactg acttcgcctg cgcgctaagc gatgtctcag taaatccttc tggtaggcgc
    12301 tcaacaacgg tctgccagta ctgcgataag ggtgaagaga gcggcgtcat ttaggggata
    12361 tcctttaaat aatgccggat ggcggcgttt cgcctgatcc ggcctacaag tccgcatacc
    12421 gtaagcctga taagcgcagc gtcatcaggc gctttctacg gttctgatta tcgttttccg
    12481 ctgtgcaacc agaacggctg ctggttgatg gcctcattac ggaaatgttc aatttcaata
    12541 cgttgcccgg taataatggc gtgacgcaat ccctgccagt tttccagcca tgcctgcgcg
    12601 accatcgcat cataataccc ggccagcagt aaaacgctgt cgatatcgcg agtcaaacgc
    12661 ggcaactggt cgcgatactt atcacccagc ggttgtccaa aaactttttt taattcagca
    12721 gcatgacgag aaagatgaat gtcggcgaaa cgcttaaaag aatcggccat tttggcctgc
    12781 gccttcgcgt ccagaaatgg ctgccaggct ttcgtcacca gccattccgt caatgccagt
    12841 ttcgccatcg ccgtttgcgt actataaacg gctgtgacgg cggacaccgc ggatgtcatc
    12901 gtcgcttccg cctgggtaag tagatcacgt aagtgagcgc tcgctttacg tggaacaatg
    12961 ccaccaaaaa gcattaaggc atggcgcact aatcccatag catccagcac atgttctttc
    13021 gccgactcgt cgccgcgcag ccagagctct tcatggtact gccactgtga caacgccaga
    13081 tccagcgagg cctccagccc ttgctctacc gtagctttcg cggcagtccg cagaattgcc
    13141 gttggtgtat tctctcgcgg cgcattcccc tgcgccaggt gataacctcg cgccgcctta
    13201 ctcagactgc cctgacgcaa accggtttgc gacagcagtt gcttcgccag ttttaacacg
    13261 gcgcgcgtat cgccgcgaag caactcaagc tccagctcac aaattggttc ggcaaactcg
    13321 cccgctttta cgtcgccgag atcgagcgca atttcaatcc tgctgccgtc aacgtccaga
    13381 caccattttt cccggtaaaa atcggtactg aacagcggct gtacgcttga tgccaggccg
    13441 tcgggcaggt tgccatccgg ccagacctcc gccggaagtt gcgtcagatc cagcacgggt
    13501 tcgcttagcg caacattgta ttcgggtcgc tggtgcagcc cgcccgttac ccggccggca
    13561 attttcatgg tcatttcata gcgcccattt tcaccacgaa tacgcagccc catatcatgg
    13621 cggcgtagcc agttatcagg cgtttcgaaa tagatattca gcaactggct gggcgcatga
    13681 tgctcgccgc cgagcgtatg aagatgattt cgcagcgcat ctacggcgtc gtgattgacg
    13741 ataaacttta attcgatttc ctgagccatg gccttgtact tatgggttat gtcacatctg
    13801 ggaagattct tggcgaactt acccgcatta tttttgtcag tagatagtat tttgcgccaa
    13861 attgccatgc aacgagcaat ttgacgggcg taaaagtttg acgtagcggc aaaggcgaca
    13921 cagatgattc cgattgatgt cgactgcttt gcgtagcgac actgatgccg ttactatcgt
    13981 tccactttct ctgacaataa cgacagcctg atgccaaaat tacgcctgat tggactaact
    14041 ttacttgcgc ttagcgccac cgccgtctct catgctgaag agacgcgtta cgtttctgat
    14101 gaactgaata cctgggtccg cagcggtccg ggagataatt atcgccttgt gggtaccgtc
    14161 aacgccggcg aggaagtcac gctcttacag agcgatgcca actatggtca aattaaagac
    14221 agttctggtc gtactgcctg gataccgtta aaagaactga ataccacgcc aagcctgcgt
    14281 acccgcgtgc cggatctgga aaatcaggtc aaaacgttaa ccgataaact caacaatatt
    14341 gataccacgt ggaatcagcg caccgccgac atgcagcaga aagtggcgca aagcgacagc
    14401 gtcatcaacg ggctaaaaga agagaaccag aagctgaaaa acgagctgat tgtcgcgcag
    14461 aaaaaagtta gcgccgcgaa tctgcaactg gatgacaaac agcgcaccat tattatgcag
    14521 tggtttatgt atggcggcgg cgtattgggt attggcttgc tgttagggct ggtgctgccg
    14581 catatgatcc caagccgtaa acgcaaagac cgctggatga actaaatcgc cttctctgcg
    14641 gcactgtctt atcattagag gatgatcgtt tttaaaagga aagtggcgtg aagatttatc
    14701 tggtcggtgg tgcggttcgg gatgcgttgt tagggctacc ggttaaagat aaagattggg
    14761 tcgttgtcgg cgccacgccg caggagatgc ttgatgcggg ctaccagcag gtaggccgtg
    14821 attttcctgt gtttctccac ccgcaaactc acgaagaata cgcgctggcg cgtaccgagc
    14881 gtaaatccgg ttccggctac acgggtttca cctgctatgc cgcgccggac gttaccctgg
    14941 aagccgacct ccagcgtcgc gatctgacca ttaatgctct ggcgcgcgac gatgacggac
    15001 agattatcga cccttaccac gggcgccggg atctggaggc gcgtctactg cgccatgtct
    15061 ctccggcgtt tggcgaagat cccttgcgcg tattgcgcgt ggcgcgtttt gccgcccgtt
    15121 acgctcatct tagtttccgt atcgccgatg aaacactgac gctaatgcgc gaaatgaccg
    15181 cggcaggcga gctggaacat ctgacgccgg aacgggtatg gaaagagacg gaaaatgcgc
    15241 ttaccacccg caatccgcag gtttacttcc aggtattgcg cgactgcggc gccctgcgcg
    15301 tcctgtttcc ggaaatcgac gccctgtttg gcgtacccgc gccggcaaag tggcatccgg
    15361 aaattgatac cggagttcat acgttgatga cgctgtcgat ggccgccatg ctcagtccgc
    15421 agcttgatgt ccgtttcgcc acgctttgtc atgatgtggg caaaggctta acgccgaaaa
    15481 acctctggcc gcgccatcat ggccacggcc cggtgggcgt gaaactggtc gaacagttat
    15541 gccagcgttt gcgcgtcccc aatgacctgc gtgatttagc taaactggtc gccgcgtacc
    15601 acgatctgat tcacaccttt ccgatactcc agccgaaaac gatcgttaag ctgtttgacg
    15661 ccattgatgc atggcgtaaa ccgcagcgcg tcgagcagat tgcgctgacc agcgaggccg
    15721 atgtccgtgg acgtaccggc tttgaagcgt cggattaccc gcaggggcgc tggctgcgcg
    15781 aagcctggca ggtggcccaa gcggtaccaa cgaaagaggt ggtggaggcc ggatttaagg
    15841 gcattgagat tcgcgaggag ctgacgaagc gacgaattgc agcggtcgcc aactggaaag
    15901 agaagcgctg cccgaacccc gccagctaaa cgccatccgg cacgataaat tgcctgatgg
    15961 cgctgcgctt atcagaccga caaaactgtt aggccggaca aggcggtacg ccgccatccg
    16021 gcacggtcaa tcatcagaag aagacaacgt aaacggcagc cgccaccaca aagcggtaaa
    16081 tcgcaaacgg aataaacgag atacgcttaa tcagttgcag gaaggtcttg atggcgatca
    16141 gcgccaccac aaacgccgtc acaaagccca ccgcgaacat tggaatatcc gctgcggtca
    16201 ggaatgacca acttttgtag agatccagaa ccgttgcgcc catcatcatc ggcacagcca
    16261 gtaagaacga gaactcggag gcggcgtaac ggctgacgcc catcagcatc ccaccggaaa
    16321 tggtcgctcc ggaacgcgag aagcccggcc acagcgccag acactggaaa cagccaatca
    16381 taaacgcctg acgatacgtc atatcatcca gccccggcgc gcgcggttct ttcggcttca
    16441 ggcactcggc ggcaatcagc aacagaccgc ctaccaccag cgcatacatc acgttaatcg
    16501 ggttaaatag cgacttgatc gtgtcatgaa agactaaccc cagcaccacc gccggaatca
    16561 tgcccagcag gatgtgaatc aacgttaatc gacctttact ttcaccttca cgctgtagcg
    16621 ggcggccaaa gtgaataccg atgagaccaa acaaccgccg ccagaacatc accacgaccg
    16681 ccagaataga tccaagttga atcaccactt cgaatgtctt ggccgtatcg ccttcaaacc
    16741 ccagcagatg acccacaata atcatatggc ccgtgctgga taccggcaaa aactccgtca
    16801 atccttcgac cacacccaaa attgccgcta tcagcagcga gtgcatatcg ctcatcaata
    16861 aacccctaaa atgaaaaaca ctgcaaaaat ggatctcgcg ttaagacccc atatataacc
    16921 gtttggttta aaaaatataa aattatttat ttttatttca gattattgcc acgctcaata
    16981 attaccccta cgttcgccgc gcgcgcgacg gcgctaggct tgctcagttt gatgcgaacc
    17041 cacggagaat tgaatcggct aagcagtaga tccgccacct cttccgccac acgctcgacc
    17101 agagcaaaac gcccgccttc aacatgattt atcaccgtgt cggcgatatc cgcgtaactt
    17161 agacaatctg cgacatcatc gcttttcgcc gacttgcggt tatcccatgc catttcgata
    17221 tcgaacacca gtttttgctc gatagtctgt tcccagtcgt aaacaccgat agtggtgatt
    17281 accgaaagtt gctctataaa tacaatatcc atcacgacct gcctgctttt tggctaaccc
    17341 ggataccact tccggcgaaa tgtgcgtatt atccacagaa atagtaaata aaacgacact
    17401 ttcaatacgg aacagcttat gagtgcaatc gcgcctggaa tgatcctctt cgcgtacctc
    17461 tgcggctcaa tttccagtgc cattctggtt tgccgcatcg ccgggctgcc cgatccgcga
    17521 gaaagcggct ccggcaaccc gggcgcgacg aacgtattac gaatcggtgg caagggagcg
    17581 gctgtcgcgg tacttatttt tgacatcctt aaaggcatgt tgcccgtctg gggcgcgtat
    17641 gcgttaggcg ttaccccttt ctggctgggg cttatcgcta tcgccgcctg tctgggacat
    17701 atctggccgg tcttttttgg ctttaaaggc gggaaaggcg tagcaaccgc gtttggcgcc
    17761 attgcgccca tcggctggga tttaaccggc gtcatggcag gcacctggct gctgacggtc
    17821 ctgttaagcg gttattcatc gttaggggcg attgtcagcg ccttgattgc gccgttttac
    17881 gtctggtggt ttaaaccgca gttcactttc ccggtgtcga tgctgtcatg tctcattttg
    17941 ctgcgccatc atgacaacat ccagcgtctg tggcgtcgcc aggagacgaa aatctggacg
    18001 aagctgaaaa agaaacgcca gaaagattga gctggaactg cgtctggaag agggcctcaa
    18061 ccgtctgggg atcggcccac aagggttgac cggcaatagc tcggtgatag gcgtacatat
    18121 cgaatccgcc gcgcgtcacc cttccaccat tggcgtggtt aggcgcgatt ttcggcctga
    18181 ttttcctggt gctgctgatc gtctccaggc tgttgtggat gcccatcgtt ttgctgtaaa
    18241 tccgttgggg cggcatgatg tcgccccctt tttccgcttt tacgccgccg gcagctcggc
    18301 cagcggccag cgcggacgta ccgttacgcc aagatccgcc gtaacgcccg ccttaaaccg
    18361 caccattccg gcataggcga tcatcgcccc gttgtcggta caaaattccg ggcgcgcata
    18421 gaacacttcg ccgcggcgtt tttgcatcat ttcggcaagc ttcgcacgca gcgtgcggtt
    18481 agcgctgacg ccgcccgcca tgacaagacg cttaaaaccg gtgctttcca gcgcgcgctt
    18541 gcacttgatc atcagcgtat ccacgaccgc atcttcaaaa gcgcgcgcga tatcagcgcg
    18601 agtttgttcg tcgtcgccat tactacgaat ggtgttagcg gcaaaggttt tcagaccgga
    18661 aaaactaaaa tccagccccg ggcgatcggt catcgggcgc ggaaagacaa aacgccccgc
    18721 cgtcccctgc gacgccattt tcgacagcat cgggccgcca ggataatcca gccccaacaa
    18781 tttggcggtt ttatcaaacg cttcaccggc ggcatcgtca atcgactctc ccagcagttc
    18841 gtactgaccg attccggtca cgctaatgag ctgcgtatgt ccgccggaga ccagcagcgc
    18901 cacaaacggg aaatccggag ggttatcttc cagcattggc gccagcagat gaccttccat
    18961 atggtgtaca ggaatggctg gcacattcca ggcaaatgcc agcgaacgcc cgacggttgc
    19021 gccgaccagc agcgcgccga ccaagcccgg gcctgcggta taggccaccg cgtcgatatc
    19081 gctcgccgtc agagcggctt cttttaatgc cgcctgaatc agcggcacgg ttttacgcac
    19141 atgatcgcgg gaagccagtt caggcactac gccgccgtaa tcagcatgta atttcacctg
    19201 actatacaat tggttggcta acagaccttt tttgtcgtcg taaatagcga tgccggtttc
    19261 atcgcaagat gtttcaatac ccagtacacg catgacttgt tttacctcgc tctaataccg
    19321 cgcagtgtag gtcgaatgcg ggtggatgta taccctcagt cccgacttcg tgtatactcc
    19381 ctccccttat aaaagtccct ttcaaaaaag gccgcggtgc tttacaaagc agcagcaatt
    19441 gcagtaaaat tccgcaccat tttgaaataa gctggcgttg atgccagcgg caaaccgaat
    19501 taatcaaagg tgagaggcac atgccggtaa ttaaagtacg tgaaaacgag ccgttcgacg
    19561 tagctctgcg tcgcttcaag cgttcctgcg aaaaagcagg tgttctggcg gaagttcgtc
    19621 gtcgtgagtt ctatgaaaaa ccgacgaccg aacgtaagcg cgctaaagct tctgcagtga
    19681 aacgtcacgc gaagaaactg gctcgcgaaa acgcacgccg tactcgtctg tactaatctt
    19741 ttgagagcgg gctgctctca attcagatcg agttgtagtt gtaaggccgt gcttccgaaa
    19801 ggaatgcgcg gcttgttttc gtttatgcat tagcatatac acaaaatcat tcatgctacg
    19861 tccaggcggc aagagagcaa gtccccggcg cttacgcaag tcagcgacag gggtgagcaa
    19921 acgtagccaa cactacggca gcctgaagaa tgacgtgtat aaaaggggca tatggctgga
    19981 cgaatcccac gcgtatttat taatgacctg ctggcgagaa ccgatatcgt cgatctgatc
    20041 gacgtgcgcg taaaactcaa gaaacagggc aagaactatc acgcgtgttg tccattccat
    20101 aatgagaaaa ccccttcttt caccgtaaac ggtgaaaaac agttttatca ctgctttgga
    20161 tgcggcgcgc atggcaatgc gatcgacttt ttgatgaatt acgacaagct cgaatttgtc
    20221 gaaaccgtcg aagaattagc ggccatgcat aacctggaaa ttccctatga agcaggcacc
    20281 gggctcagcc agatagagcg ccatcaacgg caaaacctct atcagttgat gaatggtctg
    20341 aatgactttt atcagcagtc gcttacccat cctgcggcaa aacctgcgcg tgactatctg
    20401 caaaagcgcg gtctgagcgc tgaaattatt cagcgtttcg ccattggctt cgcgccgcct
    20461 ggttgggata acgcgttaaa gcgcttcggt aataacagcg ataacaaggc attgttgctg
    20521 gatgccggaa tgctggtcaa taacgagcag ggcagcactt acgatcgttt ccgtaatcgg
    20581 gtcatgttcc ctattcggga caaacgcggc agggtgattg gttttggcgg tcgagttctg
    20641 gggaacgaca cgccgaaata ccttaactct ccggaaacgg acattttcca taaaggccgc
    20701 cagctatatg gtctttatga ggctcagcaa tatagtgctg aaccgcaacg cttgcttgtg
    20761 gtcgaaggtt atatggatgt cgtcgcacta gcgcaatacg acattaacta tgcggtcgcc
    20821 tcgctgggta cctcaaccac ggcagaccat atgcatatgt tattccgggc gacgaacaac
    20881 gtaatttgct gttacgacgg cgaccgggct ggccgtgatg ccgcctggag agcgctggaa
    20941 acagcaatgc cttatatgac cgacggtcgg caggtacgct ttatgttttt acctgacggc
    21001 gaagacccgg atacgctggt gcgtaaagaa ggcaaggcgg cttttgaagc gcggatggag
    21061 caggcgcagc cgctctctac gtttctgttt aatagcctcc tgccgcaggt ggatttaagc
    21121 tcgccggatg gcagcacgca gttagccgcg ctggcgctgc cgctcattaa tcaggtgcct
    21181 ggcgacacgc accgtattca gctgcgccag acgttggggc tgaagttagg cattttcgat
    21241 gatagtcagc ttgatcgttt agtgccaaaa caggcggaaa gcggcgtttc ccgcccggct
    21301 ccgcagctaa aacgcacgac catgcgtata ctgataggat tactggtgca aaatccggat
    21361 ctcgcgccgt tagtgccgcc cttagacgcg ctggatcaga ataagctgcc tggacttggc
    21421 ttatttaaag aattggtcaa aacttgtttg gctcagccag gtcttactac cggacaactt
    21481 ctggaactct accgtggcac aaatgatgct gcgacccttg aaaaattatc gatgtgggac
    21541 gatatagcag ataaggcgat tgccgaaaag acctttaccg actcactcaa ccatatgttt
    21601 gattcgctgc tgcaactgcg acaagaagag ctgatcgctc gcgatcgcac tcacggttta
    21661 agcagcgaag aacgccgaga gctctggacg ttaaaccagg agctggccag aaaatgaatt
    21721 taacggctta aatgccgcat atcgttcggg aagcccccga cagccgcagt gagaggcagc
    21781 ggccaaaata taagtatgcc ctcgctttaa atgtcgacag ctataccgtc gacaccaatc
    21841 aaacgaataa gtgtggatac cgtcttatgg agcaaaaccc gcagtcacag ctgaaacttc
    21901 ttgtcacccg tggtaaggag caaggctatc tgacctatgc tgaggtcaat gaccatctgc
    21961 cggaagatat cgtcgattca gatcaaattg aagatatcat ccaaatgatc aacgacatgg
    22021 gtattcaggt aatggaagaa gcgcctgatg ccgatgatct gctgctggct gaaaatacca
    22081 ccagcaccga tgaagatgcg gaagaagctg ctgcacaagt tctgtccagt gttgagtctg
    22141 aaatcggtcg tacgactgac ccggtacgca tgtatatgcg tgaaatgggc actgttgaac
    22201 tgttgacccg ggaaggcgaa atcgacatcg ctaaacgtat cgaagacggg atcaaccagg
    22261 ttcaatgctc cgttgccgaa tacccggaag ccattaccta tctgctggaa cagtacgatc
    22321 gcgttgaggc tgaagaggct cgtttgtccg atcttatcac cggctttgtc gatccgaacg
    22381 cggaagaaga gatggcgccg accgcaactc acgtcggttc tgaactctcc caggaagacc
    22441 tggatgatga cgaagacgaa gatgaagaag acggcgacga tgacgccgcc gatgacgaca
    22501 acagcattga ccctgaactg gcacgcgaaa aattcgctga actgcgcgcg caatacgtcg
    22561 ttacgcgcga caccatcaaa gcgaaaggcc gcagccatgc tgccgcgcag gaagagattc
    22621 tgaagctgtc tgaagtgttc aaacagttcc gtctggtacc gaagcaattc gactatctgg
    22681 tcaacagtat gcgcgtgatg atggatcgcg tgcgtactca ggaacgtctg atcatgaagc
    22741 tctgcgtcga gcagtgcaaa atgccgaaga agaactttat cacgctgttt accggtaacg
    22801 aaaccagcga aacctggttc aatgccgcta tcgcgatgaa caaaccgtgg tcggaaaaac
    22861 tgcacgatgt cgcggaagaa gtgcaacgct gcctgcaaaa actgcggcag atagaagaag
    22921 agaccggtct gaccatcgaa caggtgaaag acatcaaccg tcgcatgtcc atcggggaag
    22981 cgaaagcccg ccgtgcgaaa aaagagatgg ttgaagcgaa cttgcgtctg gttatttcta
    23041 tcgccaagaa atacaccaac cgaggtctgc agttcctcga tctgattcag gaaggcaaca
    23101 tcggtctgat gaaagcggta gataagttcg aataccgtcg tggttacaag ttctccacct
    23161 acgctacctg gtggattcgt caggcgatca cccgctctat cgccgaccag gcgcgcacca
    23221 tccgtattcc ggtgcatatg attgagacca tcaacaagct caaccgtatt tctcgccaga
    23281 tgctgcaaga gatgggccgc gagccaacgc cggaagagct ggctgaacgg atgctgatgc
    23341 cggaagataa aattcgtaag gtgctgaaaa tcgccaaaga gcctatctcc atggaaacgc
    23401 cgatcggcga cgatgaagat tcgcatctgg gtgatttcat cgaggatact accctcgagc
    23461 tgccgctgga ctctgccacc accgagagcc tgcgcgccgc cactcacgac gttttggctg
    23521 gcctgaccgc tcgtgaagcg aaagtcctgc gtatgcgttt cggtatcgat atgaacaccg
    23581 accacacgct ggaagaagtg ggtaaacagt tcgacgttac ccgcgaacgt atccgtcaga
    23641 tcgaagcgaa ggcgctgcgt aaactgcgcc accctagccg ttctgaagtg ctgcgcagct
    23701 tcctcgacga ttaattcgcc gtacacgtat aaacgccgcc gcaaggcggc gtttttttat
    23761 caggtcatgc gcgagcgttc tatttggcct gcagaatctc tacacaacgc gagtattcgc
    23821 gccctcattc cccattgcta tagcccacgc ataatgagcg cttgatccag ctcgcgatag
    23881 gcctcgacca gtttttccgt tttaattcgg tttaagccgc tgggattcgg caacacccac
    23941 accatcgtcg cgccaatggc gatcttttgt ttaccccagg cgataccgcg ctggctgaat
    24001 ccctgttcaa aagcctgttt accaagcacc gccagcgccg cgggctggta gtcctctatc
    24061 ttttcaatca ggttgcgtcc gccgctacgt aattcatgca acttcacctc agtcgcttgt
    24121 accgtcggtc ggtcgacgag tttcgttacc ccgcagcgaa aatccagtaa tttttccgcc
    24181 tcctccggtt tcaactgtcg atcggtgaaa ccggccaaat gaataacttt ccaaaaacga
    24241 ttcgcgggat gcgcaaacgg aaagccggta ttcgccgagg agagtcccgg attgatgccg
    24301 caaaaaacca cccgtagccc tggcgccagt atgtccttaa ccattattac tcctgagcaa
    24361 tacaacgttc tttaagtata acgggttgaa aacacattgt ttataaaaac agcacccgca
    24421 cggttacggc tggattacag cgtaaagtta cattataatc caccgccacg gccccttagc
    24481 tcagtggtta gagcaggcga ctcataatcg cttggtcgct ggttcaagtc cagcaggggc
    24541 caccaaattt tagctttaaa atcatataat taagccactc taaagagtgg cttttttgtt
    24601 tctgacaggg ctcgccccat accgctattt acgatgccaa taggctgccg cacgtaccag
    24661 gtgtggatca aacccctttt caaagcactg acttaaacgt tttaccgttt tgccttcgcc
    24721 agtaatccag atgaaatagt ctgattctgg tattgccagc tgcgacaggc gcgtttgcat
    24781 tgcctgttca tcgccgccaa caacatattc cacagtaata tccgtcaaat gggcgagata
    24841 atcgcgatat gcggcatcct gaatgctcac cagcgcggtt accgcagggc gcgcaggcag
    24901 acggctaagc gattccagac gacgacgtag cgcaggcata ccggactcat cgcagacata
    24961 aacctgacaa gcataatctt ccggcaccac cagcgaaccg cgcggcccgc caatcgtcag
    25021 tgtatcgcct tcacgggctt ccattgccca acggctggct acgccgccat cgtggataaa
    25081 gaaatccagc gccagctcgc gatgcgcctc gtcatacagc ggcgtgtaat ccctggagac
    25141 cggacgaacg ccctcccccc agataatgcc ttcctcagtg actgtcgggg gcgtaaagcg
    25201 acagcctggc tcagggaaaa aaactttcgt gtgatcgtca aagcccaggg aggtgaaacc
    25261 gtccagcgcc tcgccgccaa gtacgatccg ctgaaatcct gcgctaatac gttctacccg
    25321 cagaacggtc agctcgcgaa aacgcagttc attacgaaca cgctgtggat agcgtgcgga
    25381 tgatgtcgtc attttttg
//
LOCUS       DAJVBX010000044        25221 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.044, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000044 DAJVBX010000000
VERSION     DAJVBX010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 25221)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25221)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25221
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.044"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            30..419
                     /locus_tag="OPV72_001580"
     CDS             30..419
                     /locus_tag="OPV72_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001294874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HCR9913922.1"
                     /translation="MSEPVSSATVLAGGLMGASVFGLATGTDYGVVFGAFAGSVFYVA
                     TATNIGRIRLVAYFITSFIVGVLGAGLIGTKLAAITHYEKPLDALGAVIISAMCIKFL
                     TFLNSQDLNTLFSILSRIRGGGSDGSK"
     gene            406..687
                     /locus_tag="OPV72_001581"
     CDS             406..687
                     /locus_tag="OPV72_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004899663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HCR9913923.1"
                     /translation="MVANDPSAVLNAVICGVIVIVLMFYRRGDATHRPLISLLAYVMV
                     LVYASVPFRFVFGLYESSHWLVVMVNILICAAVLWARGNVARLVDALRH"
     gene            687..1301
                     /locus_tag="OPV72_001582"
     CDS             687..1301
                     /locus_tag="OPV72_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 19 protein"
                     /protein_id="HCR9913924.1"
                     /translation="MNQQQFQQAAGISAGLSARWYPYITAAMSEFGITAPLDQAMFIA
                     QAGHESAGFTVLKESFNYSVEALKKTFGKRLTPYQCEMLGRIDGRQVAHQPQIANLVY
                     GGRMGNKDAGDGWKYRGRGLIQITGLENYTRCGVALKLDLVANPGQLELERHAARSAA
                     WFFVTKGCLKYSGDLVRVTQIINGGQNGFGDRRERFEKAKSVLV"
     gene            1298..1837
                     /locus_tag="OPV72_001583"
     CDS             1298..1837
                     /locus_tag="OPV72_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2514 domain-containing protein"
                     /protein_id="HCR9913925.1"
                     /translation="MNLLSALLKRYWLQLAFILLMAGAFIAGNVWSDRGWQKKWADRD
                     SAESSQEVNAQTAARIIEQGRIIARDEAVKDAQAQAAKSAATAAGLSATVSQLRTEAK
                     KLATRLDAAKHTANLAAAVRSKTAGADATVLADMFGSLAEEAQYYAERSDESYRAGMT
                     CERIYNSVRESTNNPIAPH"
     gene            1880..2257
                     /locus_tag="OPV72_001584"
     CDS             1880..2257
                     /locus_tag="OPV72_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913926.1"
                     /translation="MFTVKTIINGVTHICEQPSISIARAGSETFADTLKLTHNSACPD
                     FAYWLPAIYEDPEMTKALQEEELVISDRTDVLDTDAIAIIIEEYPSENFPGAGDGCRY
                     QFIYPGDQVYVMNSHGSTIETVK"
     gene            2354..2581
                     /locus_tag="OPV72_001585"
     CDS             2354..2581
                     /locus_tag="OPV72_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913927.1"
                     /translation="MNQAIEQIIHSSLNKNEPGAGVGSSVTANDIIEGVRPYYQAASG
                     AEKLSIVERLNKLKVEPGVPIPSNIEQLLSN"
     gene            2671..3423
                     /locus_tag="OPV72_001586"
     CDS             2671..3423
                     /locus_tag="OPV72_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913928.1"
                     /translation="MAKPDWEAIETAYRAGIMSLRDIGALYGVTEGAIRKKAKKLEWV
                     RKNITQVRKNGTQKNTVRTTRRPASSGAVQKHSRPESGPPADTKPEAVRKKVVTNHPP
                     FQPGNQYALKHGGYARRLLLKDEVVEDARALTLEDELFRLRANNLMAAENIGRWFTLL
                     EDAEEEQQRKILMDNISAAEKAMMRNTVRIESIVGTLATVSKIHADTDYRLAATDKVS
                     LEADRLRRDAGIDDGNGERDLNDFYADIQTDA"
     gene            3389..4792
                     /locus_tag="OPV72_001587"
     CDS             3389..4792
                     /locus_tag="OPV72_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HCR9913929.1"
                     /translation="MTSTPISRPTLNPALRNFWTTQARNKVLYGGRSSSKSWDAAGFA
                     IFLANKYSLRFCCARQIQNKIEESVYTLLKIQIDRFGLRHRFRILNNKIINRVTGSEF
                     VFYGLWRNIEEIKSLEGIDVLWLEEAHALTEYQWKILEPTIRKEGSECWFIFNPGLVT
                     DFVWRNFVVDPPEDTLIRKINYDENPFLSDTMLKVIDAARRRDPEGFVHVYEGVPESD
                     DDAAIIKLSWIEAAVDAHKVLDFGPEGRKRIGFDVADSGADKCANVYRYGSVIYWADE
                     WKAKEDELLKSCQRTYQAAMERDADIVYDSIGVGASAGAKFSEINDDRKRENAYARRV
                     NYQRFNAGAGVHEPDDEYNGIPNKDFFANLKAQAWWLVADRFRNTFNAINNGEQYLVD
                     ELISIDSRCPLLEKLKLELTTPHRDFDRNGRVMVESKKDLAKRDIPSPNVADAFIMAF
                     APTDTSLDIWEQLGRQA"
     gene            4792..6261
                     /locus_tag="OPV72_001588"
     CDS             4792..6261
                     /locus_tag="OPV72_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000113511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1073 domain-containing protein"
                     /protein_id="HCR9913930.1"
                     /translation="MARNKQASRRTVQATADGYENFVTRVGMQTPNQHSASTYRANFT
                     SRNRMLVEWSYRSSWLIGEAVDAIPDDMTRKGIRITSEIDAKDRGTLEAQLDQLQIWD
                     ALNDVLKWSRLYGGAVGFIMIEGQAPMTPLRLETIGEGKFKGILPLDRWMINPVLTRR
                     IKEMGPNLGKPELYDVVTTATGIPAWRIHHSRLIRFDGVTLPFQQKMTENEWGMSVVE
                     RIWDRLTAFDSATVGAAQLVYKAHLRTYKVEKLRELIALGGPAFEALLKNIDLIRQFQ
                     SNEGMTLMDAKDTFETHQYSFSGLDDILSQFAEQISGAVGIPLVRLFGQSPKGFSTGD
                     ADLANYYDRVSSLQERRLRLPVRRVLDIMHRSELGKPLPDDFTFEFNPLWQMSDVDRS
                     TVAVNTTTAIVNALDAGLMTTKAAMTDLRENSDVTGIGASITDEDIENAEDEAPPGIG
                     ELVDKPPEPTGGDPISNEPTADSAGGRGYRKWALRWFKR"
     gene            6146..6883
                     /locus_tag="OPV72_001589"
     CDS             6146..6883
                     /locus_tag="OPV72_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000184960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HCR9913931.1"
                     /translation="MSTNRQSRQAEIRYRTSLRQIARAVGDIVNGHYDGSNDSVTEIM
                     EALERYSEIITPWATKVAENFTADIVRKNDEQWRKHSKTISRELRNLVSNAPPGQVMK
                     SIVAEQVKYIKSLPLEAADRVYDIQNRAIEAVVTGGRAEHFAKEIAASGDIAKSRADL
                     IARTELGRATGALDQARALSIGSNGYIWRTAEDGDVRHSHREMEGKFVEWGRPPTLDG
                     MTGHAGELPNCRCYKEIVFPNPHSYLA"
     gene            6898..8130
                     /locus_tag="OPV72_001590"
     CDS             6898..8130
                     /locus_tag="OPV72_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2213 domain-containing protein"
                     /protein_id="HCR9913932.1"
                     /translation="MKYFFNTRLGETRYQLADGSLLCRDVPIGRTGKQLYGAADLPNL
                     KPDKFGEIVVTRSPEQVFHPATLASFEGMSITILHPEDENGNVRLVNPENWKELAVGH
                     LQNVRRGTGEQSDLMLADLIVKDESAIQLIEDGLREVSCGYDAEYEQAEPGKAEQVDI
                     TGNHVALVPKGRAGNRCAIGDRDTMANQKKSWWTRMRTAIKTGDSDTMNELLDSAPAA
                     VTGDEGDLPGGVNLNINLSPQQPLPDKKPEMGGDVTGDGEDDIKTLLKALLAKLEGTA
                     TGDNADTPDDKDKKDPTGDGEDNEEETTITGDSAYRAEVIIPGIDLSRKVKPTAFKRD
                     VLAAADKTLVRQVVGDADIRKLPKQSVDMAFNAVSEIAKGRNTRSTTGDAQRPGMGMT
                     SIASLNKQNADFWSNRKG"
     gene            8135..8632
                     /locus_tag="OPV72_001591"
     CDS             8135..8632
                     /locus_tag="OPV72_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016244737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913933.1"
                     /translation="MTAYLYRMPVGIAGAISRPQDLTVEPVILKSDNAFAAYGLAGKY
                     DADGFFVPLAEGDTVDKVKGIYVRPYPTTSQPDMVRQVGTDKNFPGDAMKRGYMTVNV
                     GTDASSVKKGGVVYIVVSADASIPVPLGGITAAEVTGKTAALPDAFFTGAGDANGNAE
                     ISWKI"
     gene            8644..9585
                     /locus_tag="OPV72_001592"
     CDS             8644..9585
                     /locus_tag="OPV72_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2184 domain-containing protein"
                     /protein_id="HCR9913934.1"
                     /translation="MITFDQATVDSSGAFLIGELERLDQGLNLPLVGYTWTRDIQLRE
                     DVSIADDISSWTNTSFGVAGSGANPNGKNWVGKDSTAIAGVNVDISKDGNPLNLWGME
                     LGWTVVELAAAQQVGRPIDTQKYDGMQLKWQMDNDEQVYVGDEALGLKGLTNLVGVTL
                     NNATKTWANSTNDEILDSVNSILSNAWAASGYSVVPSDLRIPPEQYSLLASRKVSEAG
                     NQSLLTYLAVNTIAFHQNGVPLEIKAVKWLKGRGVGGKDRMVAYTNDKKYVRYPLVPL
                     QSVPVQYRGLYQIATYYGKLGAVEPVYKETLSYVDGI"
     gene            9627..9995
                     /locus_tag="OPV72_001593"
     CDS             9627..9995
                     /locus_tag="OPV72_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913935.1"
                     /translation="MAKEKLVTIHVHTPFTLTLGDQSKQEFGRGRHNVPEEVASHWFT
                     RAHAELSESGSNETDDQQPVIDSLQAQIADKDKLIADLKDALLKLQEQNDSLQAQITS
                     ARTGGNGAKDAKESKPANSK"
     gene            9961..10368
                     /locus_tag="OPV72_001594"
     CDS             9961..10368
                     /locus_tag="OPV72_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016244735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4054 domain-containing protein"
                     /protein_id="HCR9913936.1"
                     /translation="MPKNQSLPTVSDFRRDFPQFADPARYPEAQIEFRLNLADELLSE
                     NVTGKKLFPYFAELFVAHYMTLWAADSRAMLVGGPGGSTNGVQSSKSVDKVSVSYDTS
                     ATLNPDAGFWNNTRYGAEFYQLITMFGAGGRQL"
     gene            10365..10919
                     /locus_tag="OPV72_001595"
     CDS             10365..10919
                     /locus_tag="OPV72_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913937.1"
                     /translation="MSFKSGVTTRVDNAQAILDALKSLTKKDVLVGIPAEDSDRDDVS
                     FGNAGIGYINEYGSPAQNIPPRPHLVPGVKSVEDQTMPQLKAAAQAALDGNAAGAERA
                     LNRAGTVAARGVKNHIKAANFTPLADSTVEARARRGRKGAKAELARRAAGESPGTTLA
                     KPLYDTGKYLASITHVVRDKDADS"
     gene            10906..11295
                     /locus_tag="OPV72_001596"
     CDS             10906..11295
                     /locus_tag="OPV72_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001687820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail adaptor"
                     /protein_id="HCR9913938.1"
                     /translation="MPTLDVTDVLFDPDFCDFNLWVTRRVQTVDEDGIGSDSEVKTQF
                     AGVVTVDRSLENRRMQSGQVISGAILIVTTERLTQGQTGRDADIVTYQNRDYRVTFVD
                     PYTAYGAGFVQAHCELLPFDGGFPVEQ"
     gene            11270..11833
                     /locus_tag="OPV72_001597"
     CDS             11270..11833
                     /locus_tag="OPV72_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913939.1"
                     /translation="MEDFPLSNNSSTEPGWLTPVSGDPDYDEALDRLLSQWVRNVSGL
                     PTGMVRPRWQKDQPPLLPAETNWCAFGVTGWPIDNSPAFTNQTEEGAQLWRHETFECM
                     ASFYGPAGMTFASRFRDGISVAQNNAELNALGLSMGDYTGLTPFPELINQQWVRRYDI
                     TVRLRRKVVREYGIKSLVDAPVSFFGD"
     gene            11837..12982
                     /locus_tag="OPV72_001598"
     CDS             11837..12982
                     /locus_tag="OPV72_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001135544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3383 domain-containing protein"
                     /protein_id="HCR9913940.1"
                     /translation="MPQGLPVSNVVNVDVIIGPRAATGRNFGSLLILGTSTVIPVKER
                     LRLYSSKEDIGSDFGVDSPEYEAATVYFSQSPRPKEVYVGRWAKTLATGEAGAAEKLM
                     DAVNAVMGYTNWYGLGIADKEDIADDDWLKVAAAVEASGVSRILAITTSDPATFDATS
                     TGDLSYKLKAAKYGRTFVQYSSSSKYAALSAFGRAFTVNFNGSNTTITLKFKQEPGIT
                     YETLTTDQAAALDAKNCNVFVYYQNDTAILQQGVMSSGDFFDERHGLDWLQNYVQTNL
                     YNLLYTSTTKVPQTDAGVTRLLSNVEQSMDQSVTNGLVAAGVWNGGPIGQLDSGDALT
                     KGYYVYAQPISEQAQADREARKAPVIQVSCKLAGAVHFADVQINVVR"
     gene            12994..13434
                     /locus_tag="OPV72_001599"
     CDS             12994..13434
                     /locus_tag="OPV72_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3277 family protein"
                     /protein_id="HCR9913941.1"
                     /translation="MATYSFMDVTASISGPTGEIDLGYGSASSEEGITVAMGGPKNTM
                     TIGADGEVMHSLHADKSGTVTVNLLKTSPTNKKLSLAYNAQSQSSGTWGNNVIVIRNK
                     VSGDIITARSVAFQKQPDNANAKAGNTMPWVFDCGKIDQVLGEF"
     gene            13438..13890
                     /locus_tag="OPV72_001600"
     CDS             13438..13890
                     /locus_tag="OPV72_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913942.1"
                     /translation="MECSVKGHDYRVAKLSVFDQLKVTRKLLPVLAGMMSDFGGIRSL
                     LPADGKIDSAKFDALKPVFETLLPRIAEELSSLTEEDTNAIIHPCLAVVSRKHMGGWA
                     PVFNSGQLMFDDIDLLTMLQLVARVVADSLGNFLQGLPTNGTPTPPAE"
     gene            14068..16020
                     /locus_tag="OPV72_001601"
     CDS             14068..16020
                     /locus_tag="OPV72_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase catalytic"
                     /protein_id="HCR9913943.1"
                     /translation="MNAETIKDFLVSLGFGIDEAGYEKFESVLAGVTANAIKTGLAVE
                     GAALSVVAFTAKIASGLDNLYWASQRTGATVQGIQSIGYAVSQVGGSVDAARTSLESL
                     SRFVRNNPGAEGFLNRLGVQTRDASGNMRDMAAIFTGVGQELSSMPYYRANQYAQMLG
                     IDENTLMAMRRGLGGFSGQYSAMAKAIGFNADEAAKSSNRFMTSLREFGAMAGLARDK
                     IGSNLAGGLAGSLDTLRRHILDNFPRIEQTLTKAIKGILTLGDIIGRVAFRIVEGVGD
                     IIDWWGKLDKETKTLIEVIGGLVVAMRILNSTFWMSPVGLITGLIVAFGLLWEDYKTW
                     KEGGNSLIDWEKWQPAIDKAKDAMVWLRDHLLELKDSIGGWKTSLELLATFIAGAWIS
                     KVTGAFARLAGIPMPPWLKGWMAYAAYLYDDRENIVASAQSSIDYAKQNIGDGMRALG
                     IDTDFGRNPHTVKGANIQPDIPGAEPVQHAQSAKRTLADRNNNPGNIRPVGGNGFRFF
                     ESALQGWEAMKNQLMRYFTGKTTGRALQTIQDIVSTWAPAGDNNDPKKYAQDVAKWMG
                     VSPNTVLNLANPETMAALMQSMARKEGYSNWNSPLAYQAAGGSLNQQTVINVHGVNNP
                     QEAANLIADKQGAVNARAVQQLKGPA"
     gene            16020..16670
                     /locus_tag="OPV72_001602"
     CDS             16020..16670
                     /locus_tag="OPV72_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913944.1"
                     /translation="MDFLSVLLQQRTRSIGIIIPDVVITEKHTDALEITEHPVEQPTN
                     AGASGEGAGYISEHAFRRPSEVVMETGFSGGGSLLDFADTSAIGLSLGLSPKELYQEL
                     LNLQRDRIPFDVTTGKRIYNNMLIKTLEVTTDKSSENVLLATLTLREVIITSTQSIRV
                     ASKNNMTEGVGTSAVQNTGTKTTVPPNNSILKSLPQMAQKGVTTVDGYLSNLFLGR"
     gene            16674..16976
                     /locus_tag="OPV72_001603"
     CDS             16674..16976
                     /locus_tag="OPV72_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913945.1"
                     /translation="MEAVEIPLVADNQTFATTINGTVYHLSVIWRGEYWVLDLADSNG
                     SAIISGMPMITGADLLAQYRYMNLGFSLVVLCDVAGQENPTQFDLGTFSHLYVFTE"
     gene            16979..18010
                     /locus_tag="OPV72_001604"
     CDS             16979..18010
                     /locus_tag="OPV72_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000042292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913946.1"
                     /translation="MSKNWMRHFELLLVDDKGDGIKISELKVTFNIQKMPATIFNGFV
                     GNFKVYNLSPTTQNRIMQKEFSRIQVIAGYKGQPDATGNYPDENVGMIFNGDIRFTVT
                     GKDNATDSWIMLQCIDSWEGHLNASVKTTVAAGWKYSDLFSLGMKSFGPYGIESGAVP
                     DMPETVFPRGRVVYQSTARLMNHIAGQCNAYWWYENNQVNIVPEDNYIGVATVLNANT
                     GLIGRPQQTMGAGVNVRCLINPNIKLGGLIRLDQASVYRTSLSNDQIAQSPARLDESE
                     SDGNLYVNGLPGMSQPASINTDGDYIVGSIDYTGDTRGQAWYMDLLCLAKDGKELLNS
                     KGIDAAKYT"
     gene            18007..18342
                     /locus_tag="OPV72_001605"
     CDS             18007..18342
                     /locus_tag="OPV72_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000826019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913947.1"
                     /translation="MKRLLLAALLVCISFTSFADTGCGPFTINWKAQDGLARINGQKP
                     ETQKITFLKQKGDYDNVNIQWMVPGNGRWLGMDFVARNGKPILNVEVIRKNMDEPREF
                     WTYDCRKVK"
     gene            18537..19268
                     /locus_tag="OPV72_001606"
     CDS             18537..19268
                     /locus_tag="OPV72_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000050472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913948.1"
                     /translation="MSLAQPKSGELLEILGPSLTQGENLLSEFEIHAVIRDARNVPEY
                     YQGLSIEGLAKLVLGEVEEGCALCEKSLAIAPDDSVSFCNYTIALRNKGYHVKQYEII
                     KRAINSRNPRILSEVAINAAYWVDLDLLKKVMPMLNAMEVAKADDLLKCNESLDYLID
                     HENHSHDLKAIGQLMMTIAEKYRLRLAGAHAFYVMNELNTFFVEIKTDDPALLSKVNN
                     DLANELIAAGLENSECVGCFQAGDF"
     gene            19268..19696
                     /locus_tag="OPV72_001607"
     CDS             19268..19696
                     /locus_tag="OPV72_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913949.1"
                     /translation="MPVMHNCFLELARESLQHNGEQWTRNAISRSYYGMYHSALRITN
                     NLTPTHDTDGERLPGGSHMRLYTAFCNGEAAKVNGVDVDKVRKIGIKLKMLHAQRVNA
                     DYRLERKINRITAISALQDAEEIDALVDRMMNNPDDSLTA"
     gene            19755..20510
                     /locus_tag="OPV72_001608"
     CDS             19755..20510
                     /locus_tag="OPV72_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001685627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HCR9913950.1"
                     /translation="MPVSLSSQLGSKEQADTRLVGSVMSALRVSMPGIVQSFDPDTVT
                     AVVQPAIKGYEPDSNGVSQSTTLPLLVDVPVVFPRGGGCTLTFPVKAGDECLVIFADR
                     CIDFWWQNGGVQEPVDDRVHDLSDAFCIVGPQSQAQKISGISTSAAQLRTDDGAAFVE
                     VAAGHNVTVKTPGALTATAEGGTTITSPIITLNGDVTINGNLSQGMGEGGGSATMLGP
                     VTVTNDVKAGGKSLMTHTHSGVQTGGGNTGAPN"
     gene            20751..21104
                     /locus_tag="OPV72_001609"
     CDS             20751..21104
                     /locus_tag="OPV72_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913951.1"
                     /translation="MRYRREDTEGDYTFGSGDDTWLINSPEAVAQAVKTRFALWYGQW
                     FLDKTEGTPWIQSVLGKQKPETYNLAIRKRILETRGVKSILSFNTTVNTTTRRVQFFA
                     EIDTIYGTTTVTSEA"
     gene            21105..22304
                     /locus_tag="OPV72_001610"
     CDS             21105..22304
                     /locus_tag="OPV72_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001197067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HCR9913952.1"
                     /translation="MALNLDTLGLSATVTAEGISAPDYQTILDTLTSYFQQIYGSDAY
                     LEPDSKDGQMVALVALAIHDANNTAISVYNCFSPATGYGAALTSNVKINGIARKGATN
                     STVDLLLTGTAGTTITNGTVKDTNNVIWRLPDSVVIGVDGTVTATAICSKSGAVAAPA
                     GTITTINTPTRGWTSVTNPAAATVGAPAETDAELRIRQGQSVAIPSITPFEGVDGAIA
                     NIAGVTRHKLYENDTGKTDGNGLPPHSISAIVDGGDVTEIARTIRGNKGQGVRTWGKT
                     SVTVPDKYGNPHIISFSRPTDVPVYGKITLKVFAGYTSQIGVQIQQAVADYINRLMIG
                     DQVLLSRIYSPANLGVVSGGNARYYDIQELLIGKSPETVDAANINIAYDESASCKPEN
                     IIITVAA"
     gene            22301..22981
                     /locus_tag="OPV72_001611"
     CDS             22301..22981
                     /locus_tag="OPV72_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016239891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2612 domain-containing protein"
                     /protein_id="HCR9913953.1"
                     /translation="MSKYTDLITNYHATKPKFVEHIDLVTRPLAETSAAINGLISAFD
                     IDYATGIQLDILGQWIGLSRVVSQPISGVYFSWDTDGLGYDQGVWQGPYDPDSGYTSL
                     SDETYRIVLKTKIAINNWDGRNDSLPPILDAALDGSGLKMQIVDNQDMTIGIWVFPET
                     DISSVSLELIAAIRQGYLTVKAAGVWGGSIEIPSVETPSEGNRFFGFDMDNEYISGFD
                     AGSWGTLL"
     gene            22981..24492
                     /locus_tag="OPV72_001612"
     CDS             22981..24492
                     /locus_tag="OPV72_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001681975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCR9913954.1"
                     /translation="MAKNDFKPFATGKGANVTSQPDWEALPALLSGFTAGKASSAQVN
                     KALRQASFIAAALAQYTASKSGKDVLDDGDLSGFIAKMSAAFGKDFQTLDATLTALAG
                     LATGADKLPYFTGNDTAGQTDLTSVGRDIIGKASIADILTYLGLGETINLAKNAVPAT
                     RRVNSKPLTGDITLWASDVGAISADAVGEITDNGTMASANAPGWWKVAVSNSDTVVDF
                     PTYPGGSKLYSYGYLFVEKIGDVWFQHYYAHIGANAKRQDWGTVPNTSRPWVIDYNTA
                     NKPSASDVGALPITGGRLNGPLSIGTDNALGGNSIVLGDNDTGFKQNGDGILDTFANS
                     QHTVRVAPGEMQVLGAIRAGDAKRMTMTSSNNSVLNAQFHLWGDGNRPTVIELDDDQG
                     WHLYSQRNTDGSIQFVVNGQVIPDNYGNFDARYLTSGNVYTKGESDNRYVQNIQRGAP
                     VWPGKVDEYGPAEAPAGCFLTQARHDPTTAYGVTFAYRPLQMWVGNGWRTING"
     gene            24507..25025
                     /locus_tag="OPV72_001613"
     CDS             24507..25025
                     /locus_tag="OPV72_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HCR9913955.1"
                     /translation="MELKNVTRYIPDDPDYDNSFLYFRSEDGQDFYESLSKFTKKYKL
                     CIDSENIIRSVSEDVSRLYPAGFSVVEVNKLPAGFNIYGDWKYSNGTVLAVPVDYQAK
                     AETTRQKLLDAANSTIADWRTELALGEIGDDDKDSLTKWMAYIRALKTLDLSGVKDSA
                     TFTEIRWPELPQ"
BASE COUNT         6387 a         6019 c         6961 g         5854 t
ORIGIN      
        1 agaggaccca cacaaccaga gggggatgaa tgtccgaacc tgtatccagt gcgacagtgt
       61 tggctggtgg attaatgggg gccagtgtat tcggtctggc aaccggaacc gattatggtg
      121 tggtattcgg cgcttttgcc ggctcggtat tttatgtcgc cacggcaacc aacatcggac
      181 gcatcaggct ggtcgcttat tttatcacgt catttattgt gggagtgctt ggcgccgggc
      241 tgataggtac taagcttgcg gcaataacgc attatgaaaa accactggat gcacttggcg
      301 cagtaattat ttctgcaatg tgtataaagt ttctcacttt tctcaacagt caggatctga
      361 acactctgtt cagtattctc tctcgtatca ggggaggggg atcagatggt agcaaatgac
      421 ccttctgcag ttctgaatgc cgtaatttgt ggggtaatag tcatcgttct gatgttttac
      481 cgacgcggtg atgcgacaca ccgccccctg atttcgttac tggcctatgt catggtgctg
      541 gtgtatgcca gtgtcccttt ccggtttgtt tttggtttat atgaatcatc ccactggctg
      601 gtggtgatgg tgaatatcct tatctgcgcc gctgtgctgt gggctcgcgg taatgtggcg
      661 cgtctggttg atgctctgag gcactgatga atcaacaaca atttcagcag gcggctggta
      721 ttagcgccgg gctttctgcg cgctggtatc cgtatattac ggcggcaatg agcgaattcg
      781 gtatcactgc gccactggat caggccatgt ttattgcaca agcgggacat gaatcagcag
      841 gatttactgt tctgaaggaa agcttcaatt attcagtgga ggcgctgaag aagacgtttg
      901 gtaaacgcct gacgccgtat cagtgcgaaa tgctggggcg tattgatggt cgccaggttg
      961 cccaccagcc acaaatagcc aatctggttt acggtggccg catgggtaac aaagacgccg
     1021 gagatggctg gaagtatcgc gggcgtgggc ttatccagat taccgggctg gagaattaca
     1081 ccagatgtgg cgttgccctg aaactggatc tggtggcgaa tccgggacag cttgaactgg
     1141 aacgtcatgc cgcccgatcc gcagcgtggt tttttgtgac taaagggtgt ctgaaatatt
     1201 ccggcgacct ggtacgtgtt acgcagatca tcaacggagg gcagaacggc ttcggcgatc
     1261 ggcgagagcg ctttgagaaa gcaaaatcgg tgctggtatg aatctgttat ctgctcttct
     1321 gaaaagatac tggttgcagc tggcgtttat tttgctgatg gctggtgcgt ttatcgccgg
     1381 taatgtctgg agtgacaggg gctggcaaaa aaaatgggca gatcgcgaca gcgctgaatc
     1441 ctctcaggaa gtcaacgccc agaccgccgc ccgtattatt gaacagggcc gcattattgc
     1501 ccgtgatgag gctgtgaaag atgcacaagc gcaagccgct aaatctgctg ccactgctgc
     1561 tggcctgtct gccactgtta gccagctgcg taccgaagca aaaaaacttg ccacccgcct
     1621 ggacgccgca aagcacaccg caaatcttgc cgctgccgtc agaagcaaaa cagccggagc
     1681 cgacgccaca gtgctcgccg acatgttcgg aagccttgca gaagaagctc aatattatgc
     1741 tgagcgatct gacgaaagct accgcgcagg aatgacgtgt gagcgcattt acaactcggt
     1801 gagagagtca accaacaatc ccatagctcc gcactagcgg ggctttttgt tgtaacaaga
     1861 agacgaagaa ggaaatacta tgtttacagt taaaaccatc atcaacggtg ttacgcatat
     1921 ttgtgagcag ccatccatct cgatagccag ggccggttct gaaacgttcg cagatacttt
     1981 aaaacttact cataactcag cctgcccgga cttcgcatac tggctcccgg ctatctatga
     2041 agatccagaa atgaccaaag cgctgcagga ggaagaactg gttattagtg accgtactga
     2101 tgtgctggat actgatgcta ttgccatcat tattgaggaa tatccgagtg aaaatttccc
     2161 cggcgcgggt gatggctgcc gttaccagtt catctatcct ggcgaccagg tttacgtgat
     2221 gaactctcac ggctcgacca tcgaaacagt gaagtagcca ttacaaagcc tatctacggg
     2281 tgggcttgat aaaggcctgt ggtggacata tatacaagtt gtggtatgta accactcatt
     2341 ttgggtaata actatgaatc aggctattga gcaaattatt cacagctctt tgaataaaaa
     2401 cgagccaggc gctggcgttg gttcttcagt tacagctaat gatatcattg aaggggtaag
     2461 accctactac caagcagcga gtggggcgga gaaactgtct attgtcgaaa ggctaaacaa
     2521 actaaaagta gagcctggtg tcccgatccc atctaatatc gaacagctat taagtaattg
     2581 ataacaagcc gcctccgggc ggtttttatt gccatcacaa atgccacctt cgggtggctt
     2641 ttttaatggc tttaaccata ggacagcaac atggcaaaac cggactggga ggccatcgag
     2701 acggcatacc gggccggaat tatgagcctt cgcgacatag gggcgctgta cggcgtaacg
     2761 gaaggggcga taaggaagaa agcaaagaag ctggagtggg tacgcaaaaa tattacgcag
     2821 gtacgcaaaa atggtacgca aaaaaacacg gtgcgtacca cgaggaggcc tgccagctcc
     2881 ggcgcagtgc aaaagcattc gcggccagaa tccggacctc ccgcagatac gaaacccgaa
     2941 gcggtacgca aaaaggttgt cactaatcat cctccttttc agcctggtaa tcagtatgca
     3001 ctgaaacatg gcggttacgc ccggcgcctt ctactgaaag atgaagttgt tgaggatgcc
     3061 agagcgctga cgcttgaaga tgagctcttt cggctgcggg cgaataacct gatggccgcc
     3121 gagaacattg gtcgctggtt caccctgctg gaggatgcgg aggaagagca gcagcgcaaa
     3181 attctgatgg ataacatcag cgctgccgaa aaggcgatga tgcgtaacac cgtgcgcatt
     3241 gaatccatcg ttggaacgct ggcgaccgtt agcaaaatac acgccgacac tgattatcgt
     3301 ttggcggcta ctgataaggt atctctcgag gctgacaggc tgcgacgtga tgctggtatt
     3361 gatgatggta acggagaacg tgacctgaat gacttctacg ccgatatcca gaccgacgct
     3421 taatccggcc ctgagaaact tctggaccac gcaggcgcga aataaagtgc tctatggcgg
     3481 gcggtcatcg tcaaaatcat gggatgcagc cggatttgca atattcttgg caaataaata
     3541 cagcctgcgt ttttgctgcg ctcgccagat ccagaacaaa attgaagaat cggtttacac
     3601 gcttctcaaa attcagatag accggtttgg cctgcggcat cgtttccgca ttctgaacaa
     3661 caaaatcatt aaccgggtta ccggctcgga atttgttttt tatgggttat ggcgcaacat
     3721 cgaagaaatt aagtcactgg aggggatcga tgtgttgtgg ctggaagaag cccatgcact
     3781 gacggaatat caatggaaaa tactggagcc gacaatccgt aaagagggtt cagagtgttg
     3841 gtttattttt aaccctggac tggtcaccga tttcgtgtgg cgtaactttg tggtcgatcc
     3901 gccagaagat acgctgattc gcaaaatcaa ctacgacgag aatccattcc tttcagatac
     3961 catgctgaag gttatcgatg cggcaaggcg tcgtgacccg gaagggtttg tgcatgttta
     4021 tgagggcgta ccagagtctg atgatgatgc ggcaattatt aagctttcgt ggattgaagc
     4081 ggctgttgac gcgcataagg ttctggattt cggtcctgaa ggacgtaagc gcatcggttt
     4141 cgatgtcgcc gacagtggcg cggataagtg cgccaacgtc taccgttatg gctcagttat
     4201 ctactgggcc gatgaatgga aggccaaaga ggacgagttg ctgaagagtt gccagcgcac
     4261 ttaccaggct gcaatggagc gcgatgcaga tatcgtttac gactcaatcg gtgttggcgc
     4321 gtcggcgggc gcaaagttct cggaaattaa cgatgaccgg aagcgtgaga acgcatacgc
     4381 gcgacgtgtg aattaccagc ggtttaacgc cggtgcaggt gtgcatgagc cagatgacga
     4441 atacaacggc atccccaaca aagacttttt cgcaaatctt aaggcgcagg cgtggtggct
     4501 ggtggctgac cgtttcagaa atacgtttaa cgctattaac aacggagaac agtatcttgt
     4561 ggatgagctg atcagcatag attctcgttg tccgttgctt gaaaagctga aactggaact
     4621 gacaacgcct catcgcgatt tcgaccgtaa cggacgggtg atggtcgaaa gtaaaaaaga
     4681 cctcgcaaaa cgcgatatac cgtcaccaaa cgtcgccgac gctttcatta tggctttcgc
     4741 gccaaccgac acatcgctgg acatctggga acagttgggg agacaggcct gatggcacga
     4801 aacaaacaag cctcgcgacg aacggtgcag gccacggccg acggctacga gaactttgtc
     4861 acccgcgtgg ggatgcagac gcctaaccag cactccgcat cgacctaccg ggcgaacttc
     4921 accagccgca accgtatgct ggtggaatgg tcctatcgct catcctggct catcggtgaa
     4981 gcggtagatg ctatccccga cgacatgacc cgcaaaggca ttcgcatcac ttctgagatt
     5041 gacgcaaaag accgtggcac tctcgaagcg caactggatc agttgcaaat ctgggatgcg
     5101 ctgaacgacg tactgaaatg gtctcgtctc tacggcggcg cggtgggctt catcatgata
     5161 gaaggtcagg cgcccatgac cccgctacgg ctcgaaacca ttggtgaagg caagtttaag
     5221 ggtattctcc cgctcgaccg ctggatgatt aacccggtac tgacgcgccg cattaaagag
     5281 atggggccaa atctcggcaa gcccgagctt tatgatgtgg tgaccaccgc aacgggcatc
     5341 cccgcctggc gtattcacca tagccgcctg attcgcttcg atggggtgac gctgccattc
     5401 cagcagaaga tgaccgagaa cgaatgggga atgtcggttg tagagcgtat ctgggatcgg
     5461 cttactgcgt tcgacagcgc cactgtcggt gcggcgcagc tggtctacaa agcgcatctg
     5521 cggacctaca aagtggaaaa actccgtgag cttattgcac tgggcggccc ggcattcgag
     5581 gcgttgctga aaaacattga tctgatccgc cagtttcaga gcaatgaagg catgacgcta
     5641 atggatgcca aggatacctt cgaaacccac cagtacagtt tcagcggtct ggatgacatt
     5701 ctttcgcagt tcgccgagca gattagcggt gctgttggca ttccattggt gcgcctcttc
     5761 gggcagtccc ctaaaggttt ctcaacgggt gacgcagacc ttgccaacta ttatgaccgg
     5821 gtcagttcat tgcaggagcg tcgcttacgc ctgccagtgc gccgggtgct ggacattatg
     5881 catcgttcgg agctcggtaa gccgctgccg gacgatttca cgtttgagtt taacccgcta
     5941 tggcagatgt cagatgtgga ccgctcaacg gtggctgtga ataccacaac ggcgattgtc
     6001 aatgcgctgg atgcaggtct gatgacaacc aaagccgcta tgaccgacct gcgtgagaac
     6061 tccgatgtta ctggcatcgg cgcatccatt accgacgagg atatcgagaa tgccgaagac
     6121 gaagcgccac caggcatcgg cgaacttgtc gacaaaccgc cagagccgac aggcggagat
     6181 ccgatatcga acgagcctac ggcagatagc gcgggcggtc ggggatatcg taaatgggca
     6241 ctacgatggt tcaaacgata gcgtcaccga aatcatggag gccctggagc gctacagcga
     6301 aattataacg ccgtgggcga cgaaggttgc tgagaacttt accgctgaca ttgtgcgcaa
     6361 gaatgatgag cagtggcgga aacacagcaa aaccatcagt cgtgaactac gcaatctggt
     6421 gagcaatgcc ccgccagggc aggtgatgaa atccatcgtt gccgaacagg ttaagtacat
     6481 taaatcgcta cccctcgagg ctgctgacag ggtatacgac atccagaatc gggcgattga
     6541 agctgttgtg accggtggga gagcggagca ttttgctaaa gaaattgcag catcgggtga
     6601 tatagcaaag tccagggctg accttatcgc ccgtaccgaa cttggacgtg caaccggcgc
     6661 gctcgatcag gcgcgagcgc tgtcaatcgg ctcgaatggt tatatctggc gtacagccga
     6721 agatggcgac gtccggcatt ctcatcggga gatggaaggg aagtttgtcg aatggggacg
     6781 acccccaacg cttgacggca tgaccggtca cgctggcgag ctcccgaact gccgctgtta
     6841 taaagaaatc gtcttcccca accctcattc ttatctcgcc tgaatcgcag gtaaaacatg
     6901 aaatattttt tcaatacccg gctgggggaa acccgctatc agctggctga cggctcgctg
     6961 ctgtgtagag acgtgccgat aggtcgaacg ggtaagcagc tttacggcgc tgctgatctg
     7021 ccaaacctca agcctgacaa gttcggtgag atagtcgtaa cgcgctctcc tgagcaggta
     7081 ttccatccgg ccacgcttgc ctccttcgaa gggatgagca tcacgatcct gcatccggag
     7141 gatgaaaacg ggaacgtccg gttggtcaat cccgagaact ggaaagagct tgcggtcggt
     7201 catcttcaga atgtccggcg cgggactggt gagcagtctg atttgatgct ggctgacctt
     7261 atcgtcaaag acgaaagcgc cattcagctt atcgaagatg gtctgcgcga agtgtcgtgt
     7321 ggctatgacg cggaatatga acaggctgag ccgggtaagg ctgagcaggt cgatattacc
     7381 ggaaaccatg tggctcttgt ccccaaaggc agagccggaa atcgttgtgc aattggagac
     7441 agagacacaa tggcaaatca aaagaaaagc tggtggaccc gcatgcgcac ggccatcaaa
     7501 acaggtgact cggacaccat gaacgaactg ctggactcag cgccagcggc tgtaacgggg
     7561 gatgaaggtg atctgccggg cggcgtcaat ctcaacatta acctttcacc acaacaacca
     7621 ttgccggaca aaaagccgga gatgggcgga gatgtgaccg gcgacggcga ggacgatatc
     7681 aaaaccctgc tcaaggccct gctggctaag ctggaaggaa cggcaacagg cgataatgct
     7741 gacacccctg atgataaaga taagaaagac ccgaccggcg acggcgagga caacgaagag
     7801 gaaaccacga ttacgggtga ctctgcctat cgcgctgaag tcattatccc gggtatcgat
     7861 ctgagccgta aggtgaaacc gaccgcattt aaacgtgatg tgctggcggc cgcagacaaa
     7921 acactggttc gccaggttgt cggtgacgct gatatccgca aattacctaa acaatcggtt
     7981 gatatggcgt ttaacgccgt atctgagatt gcaaaaggga gaaacacccg cagcaccacg
     8041 ggcgatgcac aacgtccagg catgggcatg accagcatcg cttccctgaa caaacaaaac
     8101 gccgacttct ggtctaaccg caaaggataa tccaatgact gcatatctgt accggatgcc
     8161 tgttggcatt gccggggcta tctctcgccc gcaggactta accgtcgaac cggtgatcct
     8221 taaatccgat aacgccttcg cagcgtatgg tctggctggc aaatacgacg ctgacggctt
     8281 tttcgtgccg ctggcggagg gtgacaccgt cgacaaggtg aagggtatct acgttcgtcc
     8341 gtatccgacc acatcgcagc cagacatggt tcgccaggtg ggtactgata agaatttccc
     8401 gggcgacgcc atgaagcgtg ggtacatgac ggtaaacgtg ggtactgatg cttcgtccgt
     8461 taaaaaagga ggcgtggtgt acatcgtggt atcagccgat gcttccatcc cggttccgct
     8521 tggtgggatc acggcggcag aggtgacagg caaaacagcc gcgttacctg atgctttttt
     8581 tacgggggcc ggtgacgcta acggcaacgc agaaatctcc tggaagattt aaggaacaga
     8641 cgaatgatta cttttgatca ggcaaccgtt gatagctccg gtgcctttct catcggggag
     8701 ctggagcgac tcgaccaggg gctgaatctg ccactggtgg gttatacctg gacacgtgat
     8761 atccagttgc gcgaagacgt ctctatcgca gatgacattt ccagctggac gaataccagt
     8821 tttggcgtgg cgggttctgg cgctaatccg aatggtaaaa actgggtagg caaagattca
     8881 actgccattg ctggcgttaa tgttgatatc agtaaagacg gcaatccgct gaacctttgg
     8941 gggatggagc tgggatggac tgttgttgag ctggctgcgg cacagcaggt aggccgtccg
     9001 atcgacactc agaagtacga cgggatgcag cttaaatggc agatggataa cgacgaacag
     9061 gtttacgtcg gagacgaagc gcttggtttg aaaggtctga cgaatctcgt tggtgtgacg
     9121 ctgaacaacg caacgaagac ctgggctaac tccaccaacg atgagatcct cgacagcgta
     9181 aacagcattc tgtcgaatgc ctgggcagca tccggttatt ccgtcgtgcc ttctgatctg
     9241 cgcattccgc cagagcagta ttcattgctg gcgagccgta aggtttccga agcgggtaac
     9301 cagtcactgc tgacttatct ggctgtgaac actatcgctt tccaccagaa tggcgttccg
     9361 ctggaaatca aagcggtcaa atggctgaaa gggcgcgggg ttggcggtaa agaccgtatg
     9421 gtcgcctaca ccaacgataa gaaatacgtc cgctatccac tggttccgct gcaaagcgtt
     9481 cctgttcagt atcgtggtct gtaccagatt gcgacctact acggcaagct cggtgcggtt
     9541 gagccagtgt acaaagaaac cctgtcctac gtggacggta tctgataacc agaatggccc
     9601 cgaaaggggc cagaaggaaa ctaaaaatgg cgaaagaaaa gctggttacc atccatgttc
     9661 acaccccgtt tacgctgacg ctcggtgatc agtcaaaaca ggagtttggc cggggacggc
     9721 ataacgtacc agaagaggtc gcgtcgcact ggtttacccg ggcgcacgct gagctttccg
     9781 aaagcggatc gaatgaaact gatgaccagc aacccgttat tgacagcctt caggcgcaga
     9841 ttgccgataa agataaactg attgccgatc tgaaagacgc tctgctcaag ctgcaggagc
     9901 agaacgacag cctgcaggcg cagattactt ccgcccggac tggcggtaat ggggcgaaag
     9961 atgccaaaga atcaaagcct gccaacagta agtgattttc gccgcgactt cccgcagttt
    10021 gctgaccctg ccagatatcc cgaagcacaa atcgagttcc gtctgaatct ggccgatgaa
    10081 ctactgagcg aaaacgtcac cggcaaaaag ttgtttccgt actttgccga gttgttcgtt
    10141 gcgcactata tgacgctctg ggcggcagat agccgggcga tgctggttgg cggtccgggc
    10201 ggttcaacca atggtgttca gtcctccaag tccgttgaca aggtaagcgt cagctatgac
    10261 accagcgcga cgctaaaccc tgacgcaggc ttctggaata acacccggta tggcgctgaa
    10321 ttttatcagc tgatcacgat gttcggtgca gggggacgcc agctatgagt ttcaaaagcg
    10381 gtgtaacaac gagggttgat aacgctcagg caatactgga tgcgctaaag tcgctaacca
    10441 aaaaggatgt gctggtcggt atacctgcgg aagacagcga tcgggatgat gtgtcgttcg
    10501 gtaatgccgg gattgggtat atcaacgaat acggttcacc tgcacaaaac atcccaccac
    10561 gtccgcatct tgtacccggc gttaaatcag ttgaagacca gacgatgcca cagcttaaag
    10621 ctgcggcaca ggctgcgctt gatggtaatg cggcgggagc ggaaagagca ctcaaccgcg
    10681 caggtacagt ggctgcaaga ggggtgaaaa atcacatcaa agctgccaat tttactccgc
    10741 ttgcagatag caccgttgaa gcgcgtgcgc gccgtgggcg taaaggtgcg aaagcggaac
    10801 ttgcgcggcg tgctgctggt gaatctccgg gcaccacttt ggctaagcct ctttacgata
    10861 ctggcaaata tctcgcctca ataacccatg tagtgaggga taaagatgcc gactcttgat
    10921 gtaaccgatg ttcttttcga cccggatttt tgtgacttca acctttgggt aacgcgtcgg
    10981 gtacagacag tggacgaaga cgggattggt agcgacagcg aagttaaaac gcagtttgcc
    11041 ggggttgtta ccgttgaccg ttcactggaa aaccgccgca tgcagtccgg gcaggttatc
    11101 agtggagcaa tccttatcgt gacgactgag cgactcacgc aggggcagac tggccgtgat
    11161 gccgatatcg tgacgtatca gaaccgtgat tatcgtgtga cattcgtcga cccgtacacc
    11221 gcatatggcg ccggctttgt acaggcgcat tgcgagctgc tgccgttcga tggaggattt
    11281 cccgttgagc aataattcca gtacggagcc gggatggctt acacctgtca gcggcgatcc
    11341 ggattatgac gaggcgctcg acaggctgtt aagccagtgg gtacgcaacg tttccggttt
    11401 gccgactgga atggttcgcc cccgatggca gaaagatcag ccgccactgc tgccagctga
    11461 aacgaactgg tgcgcgttcg gcgttaccgg atggcccata gataacagtc ccgcattcac
    11521 taaccagact gaagagggcg ctcagctctg gcgacatgaa acctttgagt gcatggcgtc
    11581 attttatggc ccggcgggca tgacgtttgc gtcacgtttt cgcgatggta tttctgttgc
    11641 gcaaaacaac gccgaactga acgcgcttgg cctgtccatg ggggactaca ccggtctgac
    11701 ccctttcccg gaacttatca accagcagtg ggttcgccgt tacgacatta ctgtgcgcct
    11761 tcgtcgcaag gtggtgcgcg agtacggcat taaatcgctg gtggatgcac cagtttcatt
    11821 cttcggagat taaattatgc cgcagggatt acctgtatca aacgtcgtta atgtcgacgt
    11881 gatcattggg ccgcgcgcgg ctactggtcg aaattttggt tcactgctta ttctcgggac
    11941 atccacggtc attccggtga aagagcgtct tcgcctctac tcctcaaagg aggacatcgg
    12001 atctgatttc ggcgtggaca gccccgaata tgaagcagca acagtctatt tctcccagtc
    12061 accacgacct aaagaggtgt atgtaggtcg ctgggctaaa acactggcaa cgggtgaggc
    12121 gggtgctgct gaaaagctga tggatgcggt taacgccgta atgggctaca ccaactggta
    12181 tggtctcggt attgcagaca aagaggatat tgcagatgac gactggctga aggttgctgc
    12241 agccgtagaa gcttcgggcg tcagccgcat tctggcaatt accaccagcg atcccgccac
    12301 ctttgacgcc acttcaaccg gggatctgtc ctacaagctg aaggcggcaa aatacgggcg
    12361 cacgttcgta cagtattctt ccagcagcaa gtacgctgcg ctgtccgcgt ttggccgcgc
    12421 gtttacggtg aatttcaacg gcagcaatac caccattacc ctgaaattta aacaggagcc
    12481 ggggatcact tacgaaaccc tgacgactga tcaggcggcg gcgctggatg ccaagaactg
    12541 caacgtgttt gtgtactacc agaacgatac ggcaatcctg cagcagggcg tcatgtccag
    12601 cggtgatttc tttgatgagc gccacgggct cgactggctg cagaactacg ttcagaccaa
    12661 cctgtataac ctgctgtaca ccagtacaac caaagtgcct cagaccgatg cgggtgttac
    12721 acgtcttctg tccaatgttg agcagtctat ggatcagtcc gtgacgaacg ggctggtggc
    12781 tgctggcgta tggaacggtg gcccaatcgg gcagctggat tccggagacg cgctgacaaa
    12841 agggtattac gtctacgcgc agccgatttc cgagcaggcg caggcagacc gtgaagcacg
    12901 taaggcaccg gttattcagg tttcctgtaa gctggctggc gcagtgcatt tcgctgacgt
    12961 acagatcaac gtcgttcgct aaggggaaaa tgaatggcta cttattcttt tatggatgtc
    13021 accgcgtcca tttctggccc gactggcgag attgacctgg gctacggttc cgccagttca
    13081 gaggagggga tcaccgttgc aatgggcggc cccaaaaaca ccatgaccat cggtgctgac
    13141 ggcgaagtga tgcacagcct gcacgcggat aaaagcggta cggtaactgt caatctgctg
    13201 aagacctcgc cgacaaacaa aaaactgtcg ctggcgtata acgcacagag tcagtcctca
    13261 ggaacctggg gaaacaacgt cattgtgatc cgaaataagg tgagcggaga catcatcacg
    13321 gcgcgcagtg tggccttcca gaaacagccg gataacgcca acgcgaaagc cggtaatacg
    13381 atgccctggg tatttgactg cggcaaaatc gaccaggtac tcggagagtt ttaacagatg
    13441 gaatgttcag tcaaaggcca cgattatcgc gtggcgaaac tcagcgtttt tgaccagctg
    13501 aaagtcaccc gtaaattgct gccggtgctg gcgggcatga tgtcagattt cgggggcatt
    13561 cgctcccttc tgcctgcgga tggcaaaatc gacagcgcta agtttgatgc gcttaagccg
    13621 gtgtttgaaa ccctgctgcc gcgtatcgct gaggaactgt cttccctgac cgaagaagat
    13681 accaacgcga ttattcatcc ttgcctggct gtggtatcac gcaaacatat ggggggatgg
    13741 gccccggtgt ttaacagcgg tcagttgatg tttgacgata tcgacctgct gaccatgctg
    13801 cagctggtgg cgcgggtggt cgccgattct ctgggaaatt ttttgcaagg actccctacc
    13861 aacgggacgc ccaccccgcc agcggaataa ccttcaacag cctgccgggc ggtgaagatt
    13921 ttattcttcg cccggttctc gccttccata ttgaccagaa agaccttaac agcggcgcgg
    13981 tagatctctg ccgcatcgcg cttctcaatg actacctcga catgcgcgag gataacgatg
    14041 ctcgggtaga taaatggaga gaggttaatg aacgctgaga ctattaaaga ttttctcgtc
    14101 tcccttggat ttggcattga tgaagccgga tacgagaaat ttgaatctgt tcttgctggc
    14161 gtcaccgcaa atgccataaa aacagggctg gcggtggaag gtgcggcgct gtccgttgtt
    14221 gcgtttacgg cgaaaattgc ctccggtctg gataatctct actgggcatc tcaacgcacc
    14281 ggcgcgacgg ttcaggggat tcagtcgatt ggctacgcag tttcgcaggt gggcggtagt
    14341 gtggacgcgg cgcggacttc gctggaaagc ctctcccggt ttgtgcgtaa taatcccggc
    14401 gcggaaggct ttctgaaccg cctgggcgta cagacccggg acgccagcgg gaatatgcgc
    14461 gatatggccg ccatttttac gggcgtcggc caggagctca gcagcatgcc gtattaccgg
    14521 gctaaccagt atgcgcagat gctgggcatt gatgaaaata cccttatggc gatgcgccgg
    14581 ggtttagggg gattctccgg ccagtacagc gcgatggcaa aggccatcgg tttcaatgct
    14641 gacgaggcgg ccaaaagctc caacaggttc atgacctccc tgcgcgagtt cggcgcgatg
    14701 gcaggcttgg cccgtgacaa gatcggctct aatcttgctg gtggtctggc gggttcgctg
    14761 gacacgctgc gccgccacat cctggataac ttcccgcgca tcgagcagac cctgacgaaa
    14821 gccataaaag gtattctgac gctcggggat atcatcggtc gcgtggcgtt tcgaattgtt
    14881 gaaggtgtag gggatattat cgactggtgg ggaaaactgg ataaagaaac gaaaaccctg
    14941 atagaggtta tcggtggtct ggttgtcgcc atgcggatac ttaactctac tttctggatg
    15001 tcgcctgtag ggctgattac tggtctgatc gtggcgttcg gtctcttgtg ggaagactac
    15061 aaaacatgga aagaaggcgg taacagtctt attgactggg aaaaatggca gccagcgata
    15121 gacaaagcga aggatgcgat ggtctggctc cgtgatcacc tgctcgaact taaggactct
    15181 attggcggct ggaaaacgtc actggagctg ctggcgacct ttatcgccgg tgcgtggatt
    15241 agcaaggtaa cgggcgcatt tgccagactg gcaggtatac cgatgccgcc gtggttaaaa
    15301 ggctggatgg cctacgcggc ttacctgtat gacgatcggg agaatatcgt cgccagtgcg
    15361 cagtcgtcta tcgattatgc caaacaaaac attggcgatg gaatgcgtgc actggggatt
    15421 gataccgatt ttggccgcaa tccccacacc gtcaaaggcg ctaatattca gccggatatt
    15481 cctggagcag aacctgtaca acatgcacaa tccgcaaagc gcactttagc cgacaggaac
    15541 aacaatccgg gtaacattcg cccggtgggc ggtaacggct tccggttctt cgagtccgcc
    15601 cttcagggct gggaggcgat gaaaaaccag cttatgcgct actttacagg gaaaacaacc
    15661 gggcgggcat tacagaccat tcaggatatt gtcagtacct gggcgccggc tggtgacaac
    15721 aacgacccga aaaagtatgc gcaggatgtt gcaaaatgga tgggcgtttc accgaacact
    15781 gtgttgaacc tcgccaaccc ggaaactatg gccgcgctga tgcagtcgat ggcgcgcaaa
    15841 gaagggtatt caaactggaa cagcccgctg gcgtatcagg ccgctggtgg tagccttaac
    15901 cagcagactg ttataaatgt ccacggcgtg aacaatcctc aggaagcggc taatctgatc
    15961 gctgacaagc agggtgctgt caatgccagg gcggtacagc aattgaaagg acctgcgtaa
    16021 tggatttttt atctgttttg ctgcagcagc gaacccgctc gataggaata attattcctg
    16081 atgtggttat taccgaaaag catactgacg ctctggaaat tacggaacat ccggttgaac
    16141 aacccacgaa tgctggtgcc agtggtgagg gcgctggtta catatcagaa cacgcattca
    16201 ggcgcccttc agaagttgtg atggaaaccg gattttccgg aggcggatcg ctgcttgatt
    16261 ttgctgatac ttccgctatt ggtctttcac tggggctgag cccgaaagaa ctgtatcagg
    16321 agctgcttaa cctgcagcgg gatcgtattc ctttcgatgt gacaaccggc aagcgtattt
    16381 acaacaatat gttgataaaa acgctggagg tgacgactga caagagcagt gagaatgtgc
    16441 ttctggcgac ccttaccctc agggaggtga ttattacctc cacgcagtca atcagggttg
    16501 cctcgaaaaa caatatgacc gagggagtag ggacgtctgc tgtacagaat acaggtacca
    16561 aaacaacggt accgccgaat aattccattc tgaaatcgct gccacagatg gcgcaaaaag
    16621 gtgtcaccac tgtcgatggg tatctgagca atttatttct gggaaggtga ttcatggagg
    16681 ccgtagaaat cccactggtc gctgataatc agacttttgc caccacaatt aacggtacgg
    16741 tttatcacct gtctgtcatc tggcgcggag agtactgggt tctggatctt gctgacagca
    16801 atggttccgc cattatctca ggtatgccga tgattacggg ggctgacctg ctggcgcagt
    16861 atcgatatat gaatctcggg ttttcgctgg tggtactctg cgacgtggca ggacaggaaa
    16921 acccgacgca attcgatctc ggaacgttct cacacctcta tgtcttcacg gagtaacaat
    16981 gtcaaaaaac tggatgcgtc actttgaatt attgctggtt gacgataagg gcgacgggat
    17041 aaaaatttct gagcttaaag tcactttcaa tattcagaaa atgcctgcga ccatatttaa
    17101 tggattcgtt ggaaatttta aggtttataa cctgtcccct accactcaga accggattat
    17161 gcagaaggaa ttctcgcgta tacaggttat agccggatat aagggacaac cggatgcaac
    17221 gggtaattat cccgatgaaa acgttggtat gatattcaac ggagatatcc gttttactgt
    17281 caccgggaaa gataatgcga cagacagttg gatcatgttg cagtgtatcg acagttggga
    17341 aggccacctg aacgccagtg tgaaaaccac agtggctgcc ggctggaagt acagtgatct
    17401 tttcagcctg ggcatgaaat cattcgggcc ttatggtatc gagtcaggtg cagttcctga
    17461 catgcctgag acggtcttcc cccgtgggcg ggttgtctat cagagcacag ccaggctgat
    17521 gaatcatatc gccggacagt gtaacgctta ctggtggtat gagaacaatc aggtcaacat
    17581 tgtgccggaa gataactata tcggtgtcgc tacggtgctg aatgccaata cagggctaat
    17641 cggtaggcct cagcaaacaa tgggtgcagg cgtaaacgtc aggtgcctga ttaatccaaa
    17701 cattaagctg ggtgggctta ttcgtctgga tcaggcatct gtctaccgga cctctttgag
    17761 taatgaccag atagcgcaat ctccagcacg gctggatgaa tcggaaagcg acggtaatct
    17821 ctacgttaac ggcctgcccg gcatgtcaca gcctgccagc attaatactg acggtgatta
    17881 cattgtgggc agcatcgatt atactggcga cactcgcggg caggcgtggt atatggacct
    17941 gctttgcctg gctaaagatg gcaaagaatt gcttaactcg aaagggattg atgcggcgaa
    18001 atacacatga aaagactatt gttggcagct ttacttgtct gtatctcctt cacttccttt
    18061 gctgataccg ggtgcggacc attcacgatc aactggaaag cgcaagacgg acttgcaagg
    18121 attaatggac agaaaccgga gacacagaaa atcacctttc tcaaacaaaa aggggattat
    18181 gacaatgtga acatccaatg gatggttccg ggtaatggac gttggttagg gatggacttt
    18241 gtggccagaa atggcaagcc gatcctcaat gttgaagtta tccgcaaaaa tatggacgag
    18301 ccgcgagagt tctggacgta tgactgccgg aaggtgaagt gaacgcgctt ttccttgtaa
    18361 gaaggtgcct cggtgaaact aaatcgattg acatttctag ctaaccaaac tttctgaaaa
    18421 tcagcaaaat gtgcgcatcg tgctgtcgtt ttccaacttt acccattaca ctgcagatac
    18481 ttttgaaggc gttttgccat caactttgat gtcacccagt caggaattac aactaaatga
    18541 gtttagcgca gcctaaatcc ggagagcttt tagagatcct tggtccctca ctcactcagg
    18601 gagaaaacct actcagtgag tttgaaattc atgccgtcat tcgtgacgcc aggaatgttc
    18661 ctgaatatta tcaagggctt tctatcgagg gattagctaa gcttgtttta ggcgaagttg
    18721 aagagggatg tgccctttgt gaaaagtcat tggcgatagc cccggacgat tctgtttcgt
    18781 tttgtaacta tacgattgcg ttgagaaaca aggggtatca cgttaagcaa tacgagatta
    18841 ttaagagagc gatcaactcg cgtaatcctc gaattctttc tgaagtggct ataaatgctg
    18901 cgtattgggt ggatttagat ttgctgaaaa aggtaatgcc tatgcttaat gcgatggaag
    18961 ttgctaaggc agacgatttg ctcaagtgta atgagtcgct tgattatctt atcgatcatg
    19021 agaatcattc tcatgacctt aaggcgatcg gccaattgat gatgactatt gctgaaaagt
    19081 atcgtttacg tctggctggt gcgcatgctt tttatgtcat gaatgagctg aacacatttt
    19141 tcgtagaaat taaaactgac gacccagcac ttttgtcaaa agtgaataac gaccttgcca
    19201 atgaactcat cgctgctggt ttggaaaatt cagagtgtgt tggttgtttc caggcaggag
    19261 acttctaatg cctgttatgc ataattgttt tctcgaatta gccagagaat cattgcagca
    19321 caatggtgag caatggacac gtaatgctat cagcaggtca tactacggca tgtatcattc
    19381 agccctcaga atcactaaca atctgacgcc tacccatgat actgatggtg agagattacc
    19441 tggcggttct cacatgcgac tctatacagc tttttgtaac ggtgaggctg ctaaagttaa
    19501 cggcgtagat gttgataaag tccgtaaaat tggcattaag ttaaagatgt tacatgctca
    19561 gcgcgtaaat gctgattaca gacttgaacg caaaattaat cgaattacgg caattagtgc
    19621 cttacaagat gctgaagaga tagatgctct agtggaccga atgatgaata accccgacga
    19681 ctcgttaaca gcataagcta tgactaccat accaagcccg ccgatgagcg ggttttttta
    19741 tgtctggaga aaatatgcca gtttcacttt cctctcaact cggcagtaaa gaacaggctg
    19801 atacaaggct tgttggttct gtcatgtctg cactgcgagt ttcaatgcct ggcatcgtcc
    19861 agtcatttga tcccgacacc gtaaccgcag ttgttcaacc cgctatcaaa ggctatgagc
    19921 cggattcgaa tggcgttagc cagtcgacga cattaccgct gctggtggat gtgccggtgg
    19981 tatttcctcg cggcggtggc tgcacgctaa cgttcccggt taaagctggt gatgagtgtc
    20041 tggtgatttt tgccgatcgc tgcatcgatt tctggtggca gaacggcggg gtacaggagc
    20101 ctgtcgacga tcgggtgcat gatttatcgg atgcgttctg tatcgtcggg ccgcagtcgc
    20161 aggcgcagaa aataagcgga atcagcacca gcgccgcaca attgcgtacc gatgatgggg
    20221 ctgcttttgt ggaagtggcc gcaggccata acgttactgt taaaaccccc ggcgcgctga
    20281 cggctactgc agaaggcgga accacgatca catcacccat cattacgcta aacggtgacg
    20341 taaccattaa cggcaatctg tcgcagggga tgggtgaggg cggcggtagc gcaacgatgc
    20401 tcggtcctgt cacggtgaca aacgatgtga aggcgggcgg taagagcctg atgacgcaca
    20461 ctcatagcgg cgttcagacg ggtggcggga atactggcgc gccgaattaa aaactaccaa
    20521 ccagacaaaa gccccgggtg cgctaacact tcggggcttt ttactttcta caccttgagg
    20581 atggcaaggg agaacatgtg attgatttta gcaaactgat aatggagttg cgagttatgg
    20641 gcgaaaaatt acccaactgg aaattcctgc ttatatggat tgtatttttc cttttcgggc
    20701 tttcgagcct gattggtgcc gtccgatggt ggtgaataag gaggtcagac atgcgatacc
    20761 gacgcgaaga taccgaaggt gattacactt ttggtagtgg cgatgatacc tggctgatta
    20821 actcgccaga agctgtcgcg caggcggtaa aaacacgatt tgcattgtgg tacgggcagt
    20881 ggttcctcga taagacagag ggaacaccgt ggattcagtc tgtgctcggt aagcaaaagc
    20941 cggaaaccta caatctggcg atccgcaagc gcatcctcga aacgcggggc gtgaaatcca
    21001 tcctctcttt caataccaca gtgaacacga cgacgcgccg cgtccagttt ttcgctgaaa
    21061 tcgacactat ctacggaaca acgacagtaa ccagcgaggc ataaatggcc ctcaatttgg
    21121 acacactcgg cttatcggca acggtaaccg ctgaggggat cagtgcgcct gattaccaga
    21181 cgatactcga taccctgacg agctatttcc agcagattta tggtagtgac gcttatctgg
    21241 agccggacag caaagacggc cagatggtgg cgctggtggc gctagctatt cacgatgcca
    21301 ataacacagc catttccgtc tataactgct tctcacctgc tacaggttac ggcgcagcgc
    21361 tgaccagtaa cgtaaaaatt aacggtatcg cgcgcaaagg tgcaacgaac tctaccgtgg
    21421 atttactgct cactggcacc gcaggaacaa ccattacgaa cggcaccgtg aaagacacca
    21481 ataacgtgat ctggcgtctt ccggattcag tggtgattgg tgttgatggc accgtgacgg
    21541 caactgcaat ttgttccaaa agcggagcgg ttgcagctcc tgccgggacg attaccacta
    21601 tcaatacacc gacccgtggc tggacgtcag taaccaaccc ggcagcggcc accgttggcg
    21661 cacctgcaga aacggacgca gaactgcgca tcaggcaggg gcagagtgtc gcgataccat
    21721 ccatcacacc atttgaaggc gtggacgggg cgatcgctaa tattgctggt gtgacgcgcc
    21781 acaagctcta tgaaaatgat acaggaaaga ctgacggtaa cgggcttcct ccgcattcca
    21841 tctcggccat tgttgatggt ggcgatgtaa ccgaaatagc gaggaccatc cggggaaata
    21901 aagggcaggg ggtccggacc tggggaaaaa catccgtaac cgtaccggat aaatatggta
    21961 atcctcacat aatcagtttt tcgcgaccaa ctgatgtccc tgtttacgga aaaatcacct
    22021 taaaagtttt tgccgggtac acctctcaga taggtgtgca gattcagcag gctgttgcgg
    22081 attacattaa cagactgatg attggtgacc aggtactgct gagccggatt tattctcctg
    22141 ctaaccttgg ggtcgtcagt ggtggtaatg cgcgctatta cgatattcag gagttgctga
    22201 tcggcaaatc tcctgaaacc gttgatgcgg cgaatattaa tattgcttac gacgaatctg
    22261 cctcctgtaa gccggaaaat atcattatta cggtggcagc atgagcaaat atacggactt
    22321 aattactaac tatcatgcga caaaacctaa attcgttgaa cacatcgatt tagtgaccag
    22381 gccgttagct gaaacctcag ccgcaataaa tgggctaata agcgcttttg atattgatta
    22441 tgcgacagga atacaactcg atattctcgg ccagtggata gggttaagcc gtgttgtaag
    22501 ccagccaata agcggtgtct atttcagttg ggacactgac ggacttggat atgaccaggg
    22561 cgtctggcag gggccatatg atccggattc gggttatacc tcgctgagcg atgaaaccta
    22621 tcgcatcgtt ctaaaaacga agatagcaat taacaactgg gacggaagaa acgactccct
    22681 gcctcccatt cttgacgccg cactggacgg gtccggtctg aagatgcaga tcgtcgataa
    22741 ccaggatatg accataggta tctgggtttt tcctgaaaca gatatttcat cggtctctct
    22801 cgaacttatt gctgcgatac gacaagggta tctgacggta aaggccgctg gtgtatgggg
    22861 cggaagtatt gaaatacctt cggtggaaac gccttctgaa ggaaacaggt tttttgggtt
    22921 tgatatggat aacgaatata tcagcgggtt tgatgccggt tcatggggga cattactctg
    22981 atggctaaaa atgattttaa accgtttgcg acgggtaagg gtgctaatgt tacatcacag
    23041 cctgactggg aagcgctgcc ggcgctcctg tctggtttta ctgcgggcaa ggcatcaagt
    23101 gcacaggtaa ataaagcgct gcgtcaggcg agcttcatcg ctgcagcact ggcacagtac
    23161 acagccagta agagcggaaa ggatgtactc gatgatggtg acctgagcgg ctttatcgcc
    23221 aaaatgtccg ctgcgttcgg taaggatttt cagactcttg atgccacgct gacggcgctc
    23281 gctggtctgg ctactggtgc agataaactt ccgtatttca cggggaatga tacagccgga
    23341 cagacagatc ttacttctgt tgggcgcgac atcatcggaa aagccagtat tgcggatatt
    23401 ctcacatacc tcggtttagg cgaaacgata aatctggcaa aaaatgccgt cccggcgaca
    23461 cggcgggtta acagtaaacc actgaccggt gatatcactt tgtgggcgtc agatgtgggg
    23521 gccatttccg ccgatgctgt tggagaaatt accgataacg gcacaatggc atcagctaat
    23581 gcacccggat ggtggaaggt ggcggtgtcg aattctgata cggtcgttga ttttcccacc
    23641 tatccgggtg gcagcaagtt gtacagctat ggatatctgt ttgttgagaa aatcggagac
    23701 gtctggtttc agcattatta tgcccatatt ggcgcgaacg caaagcgcca ggactgggga
    23761 actgtaccga ataccagtcg cccgtgggtt attgactaca acaccgcaaa taaaccgtca
    23821 gccagtgatg tgggtgcatt gccgattacc ggagggcgtc ttaacggtcc gctaagcatt
    23881 ggtactgata atgcgctggg cggcaattcg atcgttcttg gtgataatga cactggtttt
    23941 aaacagaacg gcgatgggat actggatacg tttgcgaata gccagcacac cgttcgtgtc
    24001 gctcccggtg aaatgcaggt tctgggagcc attcgcgcag gcgatgccaa acgaatgacc
    24061 atgactagct caaataactc cgtgctgaat gctcaatttc atttgtgggg tgacggaaat
    24121 cgaccaacgg ttattgagct ggatgacgac cagggatggc atttatacag ccagcgtaat
    24181 accgatggca gtattcagtt tgttgttaat ggacaagtta ttccggataa ttacggtaat
    24241 ttcgacgccc gttatttaac atcaggaaac gtatatacaa aaggcgaatc agataatcgt
    24301 tatgtccaaa atatccagcg cggtgctcct gtatggcctg gcaaagtaga tgaatatgga
    24361 ccagcagaag cgcctgctgg ttgcttttta acacaggcca gacatgaccc aacaacagca
    24421 tacggtgtga catttgcgta tagaccgcta caaatgtggg tgggtaatgg ctggcgtaca
    24481 attaatggat aatttaggtg aatataatgg aattaaaaaa cgtaaccaga tacattcctg
    24541 atgacccgga ttatgataac agctttctgt attttcgtag tgaagatggt caggattttt
    24601 atgagtcgct gagtaaattc acgaaaaaat ataagttgtg cattgattct gaaaatataa
    24661 tccgttccgt atcagaagat gtgtcgcgac tctatccggc tggcttttca gttgttgagg
    24721 tcaataaact accagccgga tttaatatct atggcgactg gaaatattcg aacggcactg
    24781 ttctggctgt tcccgttgac tatcaggcta aggccgaaac cacccgacag aaactactgg
    24841 atgccgctaa cagcaccatt gccgactggc gaaccgaact ggcgttgggt gaaatcggtg
    24901 acgacgataa ggacagcctg actaaatgga tggcgtatat cagggcgctt aaaacgctgg
    24961 atttgagcgg cgtgaaagac tcagccacct tcacggaaat caggtggcct gaattaccac
    25021 aataacgact actactgact tgctagtttt taggtgttaa ttcggttcag gtatctgtac
    25081 gaagtcacta agatataagt aaattttctt tagaaaagaa aaaactactg tacttattat
    25141 ttacttttaa actaaatatt tacttaacaa tcaagagata ttcaaggaaa actttctttt
    25201 ctgctttatc ctgataaaag g
//
LOCUS       DAJVBX010000045        24914 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.045, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000045 DAJVBX010000000
VERSION     DAJVBX010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 24914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24914
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.045"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(215..3418)
                     /gene="rne"
                     /locus_tag="OPV72_001614"
     CDS             complement(215..3418)
                     /gene="rne"
                     /locus_tag="OPV72_001614"
                     /EC_number="3.1.26.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease E"
                     /protein_id="HCR9913956.1"
                     /translation="MKRMLINATQQEELRVALVDGQRLYDLDIESPGHEQKKANIYKG
                     KITRIEPSLEAAFVDYGAERHGFLPLKEIAREYFPANYSAHGRPNIKDVLREGQEVIV
                     QIDKEERGNKGAALTTFISLAGSYLVLMPNNPRAGGISRRIEGDDRTELKEALASLEL
                     PEGMGLIVRTAGVGKSAEALQWDLSFRLKHWEAIQKAAESRPAPFLIHQESNVIVRAF
                     RDYLRQDIGEILIDNPKVMEMARQHIAALGRPDFSSKIKLYTGEIPLFSHYQIESQIE
                     SAFQREVRLPSGGSIVIDSTEALTAIDINSARATRGGDIEETAFNTNLEAADEIARQL
                     RLRDLGGLIVIDFIDMTPVRHQRAVENRLREAVRQDRARIQISHISRFGLLEMSRQRL
                     SPSLGESSHHVCPRCSGTGTVRDNESLSLSILRLIEEEALKENTQEVHAIVPVPIASY
                     LLNEKRTAVNAIETRQDGVRCVIVPNDQMETPHYSVLRVRKGEETPTLSYMLPKLHEE
                     AMALPSEEEYAERKRPEQPALATFAMPDVPPAPTPVEPAVSVATAKKDNVAAEQPAQP
                     GLFSRFLNALKQLFSGEETKTVETAAPKAEEKAERQQDRRKPRQNNRRDRNERRDTRD
                     NRARRDGGESRDDNRRNRRQAQQQNAEARDTRQQETAEKVKTGDEQQQTPRRERSRRR
                     NDDKRQAQQEVKALNREEQPVQETEQEERVQQVQPRRKQRQLNQKVRFTNSTVVETVD
                     TPVVVDEPRPVENVEQPVPAPRTELAKVDLPVVADIAPEQDDSVEPRDNTGMPRRSRR
                     SPRHLRVSGQRRRRYRDERYPTQSPMPLTVACASPEMASGKVWIRYPIVRPQETQVVE
                     EQREADLALPQPVVAEPQVIAATVALEPQASVQAVENVAVEPQTVAEPQAPEVVKVET
                     THPEVIAAPVDEQPQLIAESDTPEAQEVIADAEPVAETADASITVAENVADVVVVEPE
                     EETKAEAAVVEHTAEETVIAPAQVVEKPQDVVCVDDHNHASAPMTRAPAPEYVPETPH
                     HSDWQRPSFHFEGKGAAGGHSATRHASAPATRPQPVE"
     gene            3992..4951
                     /gene="rluC"
                     /locus_tag="OPV72_001615"
     CDS             3992..4951
                     /gene="rluC"
                     /locus_tag="OPV72_001615"
                     /EC_number="5.4.99.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(955/2504/2580) synthase
                     RluC"
                     /protein_id="HCR9913957.1"
                     /translation="MKTETPSVKIVAIAADEAGQRIDNFLRTQLKGVPKSMIYRILRK
                     GEVRVNKKRIKPEYKLESGDEVRIPPVRVAEREEEAVSPHLQKVAALADVILYEDDHI
                     LVLNKPSGTAVHGGSGLSFGVIEGLRALRPEARFLELVHRLDRDTSGVLLVAKKRSAL
                     RSLHEQLREKGMQKDYLALVRGQWQSHVKTVQAPLLKNILQSGERIVRVSQEGKPSET
                     RFKVEERYAFATLVRCSPVTGRTHQIRVHTQYAGHPIAFDDRYGDREFDQQLTEAGTG
                     LKRLFLHAAALKFTHPGTGDVMRIEAPMDKQLKRCLEVLRSKA"
     gene            complement(5034..5618)
                     /gene="maf"
                     /locus_tag="OPV72_001616"
     CDS             complement(5034..5618)
                     /gene="maf"
                     /locus_tag="OPV72_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003836743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HCR9913958.1"
                     /translation="MPRLILASTSPWRRALLEKLTIPFECAAPDVDETPMPGEAPRQL
                     VLRLAQAKAQSLAARFPNHLIIGSDQICVLDGEITGKPLTEEKARQQLAKASGSIVTF
                     YTGLALYNSASGHLQTEVEPFDVHFRHLSEAEIDDYVRKEHPLHCAGSFKSEGLGIAL
                     FERLEGRDPNTLIGLPLIALCQMLRREEMNPLNA"
     gene            5816..6337
                     /gene="yceD"
                     /locus_tag="OPV72_001617"
     CDS             5816..6337
                     /gene="yceD"
                     /locus_tag="OPV72_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA accumulation protein YceD"
                     /protein_id="HCR9913959.1"
                     /translation="MQKVKLPLTLDPVRTAQKRLDYQGIYTPDQVERVAESVVSVDSD
                     VECSMSFAIDNQRLAVLTGDAVVTVSLECQRCGKPFTHQVHTTYCFSPVRSDEQAEAL
                     PEAYEPIEVNEFGEIDLLATVEDEIILALPVVPVHDSEHCEVSEADMVFGELPDEAQK
                     PNPFAVLASLKRK"
     gene            6389..6562
                     /gene="rpmF"
                     /locus_tag="OPV72_001618"
     CDS             6389..6562
                     /gene="rpmF"
                     /locus_tag="OPV72_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HCR9913960.1"
                     /translation="MAVQQNKPTRSKRGMRRSHDALTAVTSLSVDKTSGEKHLRHHIT
                     ADGYYRGRKVIAK"
     gene            6696..7775
                     /gene="plsX"
                     /locus_tag="OPV72_001619"
     CDS             6696..7775
                     /gene="plsX"
                     /locus_tag="OPV72_001619"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HCR9913961.1"
                     /translation="MTRLTLALDVMGGDFGPSVTVPAALQALNANSQLTLLLVGNPDI
                     ITPLLAKADFEQRSRLQIIPAQSVIASDARPSQAIRASRGTSMRVALELVKEGRAEAC
                     VSAGNTGALMGLAKLLLKPLEGIERPALVTVLPHQQKGKTVVLDLGANVDCDSTMLVQ
                     FAVMGAVLAEEVVGIKNPRVALLNIGEEETKGLDSIREASLMLKTVPTINYIGYLEAN
                     ELLTGKTDVLVCDGFTGNVTLKTMEGVVRMFLSLLKSQGEGKKRSWWLLLLKRWLQKS
                     LTRRFSHLNPDQYNGACLLGLRGTVIKSHGAANQRAFAVAIEQAVQAVQRQVPQRIAA
                     RLESVYPAGFEPLDDGKGVNLRAHR"
     gene            7855..8808
                     /gene="fabH"
                     /locus_tag="OPV72_001620"
     CDS             7855..8808
                     /gene="fabH"
                     /locus_tag="OPV72_001620"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HCR9913962.1"
                     /translation="MYTKIIGTGSYLPEQVRTNADLEKMVETSDEWIVTRTGIRERHI
                     AAPNETVATMGFTAANRAIEMAGIDKDQIGLIVVATTSATHAFPSAACQIQSMLGIKG
                     CPAFDVAAACAGFTYALSIADQYVKSGVVKHALVVGSDVLARTCDPGDRGTIIIFGDG
                     AGAAVLSASEEPGIISTHLHADGRYGELLTLPNADRVNPDNPIYLTMAGNEVFKVAVT
                     ELAHIVDETLAANNLDRSELDWLVPHQANLRIISATAKKLGMSMDNVVVTLDRHGNTS
                     AASVPCALDEAVRDGRIKAGQLVLLEAFGGGFTWGSALIRF"
     gene            8824..9753
                     /gene="fabD"
                     /locus_tag="OPV72_001621"
     CDS             8824..9753
                     /gene="fabD"
                     /locus_tag="OPV72_001621"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HCR9913963.1"
                     /translation="MTQFAFVFPGQGSQSVGMLAEMAANYPIVEETFAEASAALGYDL
                     WALTQQGPAEELNKTWQTQPALLTASVALWRVWQQQGGKMPALMAGHSLGEYSALVCA
                     GVINFADAVRLVEMRGKFMQEAVPEGTGGMSAIIGLDDASIAKACEESAEGQVVSPVN
                     FNSPGQVVIAGHKEAVERAGAACKAAGAKRALPLPVSVPSHCALMKPTADKLAVELAK
                     ITFSAPTVPVVNNVDVKCETDAAAIRDALVRQLYNPVQWTKSVEFIAAQGVEHLYEVG
                     PGKVLTGLTKRIVDTLTASALNEPAALSAALTQ"
     gene            9766..10500
                     /gene="fabG"
                     /locus_tag="OPV72_001622"
     CDS             9766..10500
                     /gene="fabG"
                     /locus_tag="OPV72_001622"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase FabG"
                     /protein_id="HCR9913964.1"
                     /translation="MSFEGKIALVTGASRGIGRAIAETLVARGAKVIGTATSENGAKN
                     ISDYLGANGKGLMLNVTDPASIESVLENIRAEFGEVDILVNNAGITRDNLLMRMKDDE
                     WNDIIETNLSSVFRLSKAVMRAMMKKRCGRIITIGSVVGTMGNAGQANYAAAKAGLIG
                     FSKSLAREVASRGITVNVVAPGFIETDMTRALSDDQRAGILAQVPAGRLGGAQEIASA
                     VAFLASDEASYITGETLHVNGGMYMV"
     gene            10656..10892
                     /gene="acpP"
                     /locus_tag="OPV72_001623"
     CDS             10656..10892
                     /gene="acpP"
                     /locus_tag="OPV72_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016535861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HCR9913965.1"
                     /translation="MSTIEERVKKIIGEQLGVKQEEVTNNASFVEDLGADSLDTVELV
                     MALEEEFDTEIPDEEAEKITTVQAAIDYINGHQA"
     gene            10978..12219
                     /gene="fabF"
                     /locus_tag="OPV72_001624"
     CDS             10978..12219
                     /gene="fabF"
                     /locus_tag="OPV72_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HCR9913966.1"
                     /translation="MSKRRVVVTGLGMLSPVGNTVESTWKALLAGQSGISLIDHFDTS
                     AYATKFAGLVKDFNCDDIISRKEQRKMDAFIQYGIVAGVQAMQDSGLEVTEENASRIG
                     AAIGSGIGGLGLIEENHSSLVKGGPRKISPFFVPSTIVNMVAGHLTIMYGLRGPSISI
                     ATACTSGVHNIGHAARIIAYGDADAMVAGGAEKASTPLGVGGFGAARALSTRNDNPQA
                     ASRPWDKERDGFVLGDGAGMLVLEEYEHAKARSAKIYAEIVGFGMSSDAYHMTSPPEN
                     GAGAALAMVNALRDAAIEPAQIGYVNAHGTSTPAGDKAETQAVKSVFGDAASRVMVSS
                     TKSMTGHLLGAAGAVESIFSILALRDQAIPPTINLDNPDEGCDLDFVPHEARQVSDLE
                     YALCNSFGFGGTNGSLIFKKI"
     gene            12343..13152
                     /gene="pabC"
                     /locus_tag="OPV72_001625"
     CDS             12343..13152
                     /gene="pabC"
                     /locus_tag="OPV72_001625"
                     /EC_number="4.1.3.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate lyase"
                     /protein_id="HCR9913967.1"
                     /translation="MFLINGHAQDQLAVSDRATQFGDGSFTTARIVDGNICHLEAHLQ
                     RLQVACEKLRIAFSHWSTLRQEMTMLATGHDSGVLKVIISRGSGGRGYSAMNCQAATR
                     ILSVSAYPAYYSQWRKQGITLTLSPIPLGRNPYLAGLKHLNRLEQVLIRSHLEQTDAD
                     EALVLDSEGWVTECCAANLFWRTGDIVFTPRLDQAGVNGIMRQFCLRQLAQSPFQVLE
                     VQAREEAVRQADEIIICNALMPIIPIRAYHGTSYSSRTLFQFLAPFCEHPN"
     gene            13155..14171
                     /gene="yceG"
                     /locus_tag="OPV72_001626"
     CDS             13155..14171
                     /gene="yceG"
                     /locus_tag="OPV72_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein YceG"
                     /protein_id="HCR9913968.1"
                     /translation="MKKLSGVFLLLLVVLGIATGVGMWKVRHLANSTLLIKNETIFTL
                     KAGTGRLALGDQLYDEKIINRPRVFQWLLRVEPELSHFKAGTYRFTPGMTVREMLELL
                     ESGKEAQFPLRFVEGMRLSDYLKQLREAPYIRHTLPDDDYATVAQALKLAHPEWVEGW
                     FWPDTWMYTANTSDVAILKRAHQKMVKAVDTVWKGRAEGLPYKDQNQLVTMASIIEKE
                     TAVASERDQVASVFINRLRIGMRLQTDPTVIYGMGTSYNGNLSRADLEKPTAYNTYTI
                     TGLPPGPIASPSEASLQAAAHPAKTPYLYFVADGKGGHTFNTNLASHNRSVQEKVLKE
                     KNGQ"
     gene            14161..14802
                     /locus_tag="OPV72_001627"
     CDS             14161..14802
                     /locus_tag="OPV72_001627"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HCR9913969.1"
                     /translation="MGSNYIVIEGLEGAGKTTARDVVVETLEQLGIRNMIFTREPGGT
                     QLAEKLRSLVLDIRSVGDEVITDKAEVLMFYAARVQLVETVIKPALAQGVWVIGDRHD
                     LSTQAYQGGGRGIDQTMLATLRDAVLGDFRPDLTLYLDVTPEVGLKRARARGDLDRIE
                     QESFDFFNRTRARYLELAAQDSRIRTIDATQPLDAVMRDIRATVTKWVQEQAA"
     gene            14799..15803
                     /gene="holB"
                     /locus_tag="OPV72_001628"
     CDS             14799..15803
                     /gene="holB"
                     /locus_tag="OPV72_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HCR9913970.1"
                     /translation="MKWYPWLRPAYEKLVESYQAGRGHHALLIQALPGMGDEALCYAL
                     SRYLLCQQPEGHKSCGHCRGCQLMQAGTHPDYYTLTPDKGKSSLGVDAVREVSEKLYE
                     HSRLGGAKVVWIADAALLTDAAANALLKTLEEPPEQTWFFLASPEPARLLATLRSRCR
                     LHHLAPPSESYAMSWLSREVTASQEALLTALRLNAGSPGAALALLQSERWAQREALCQ
                     ALMDSLHTGDWYALLTALNHEQAPARLHWLATLLVDALKRQHGASYLTNVDADAVVAA
                     LAGPLSPARIQAILNDVCHCRDQLLHVTGLNRELVLTDLILRIEHYLQPGTLLPVPHL
                     "
     gene            15814..16611
                     /locus_tag="OPV72_001629"
     CDS             15814..16611
                     /locus_tag="OPV72_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HCR9913971.1"
                     /translation="MFLVDSHCHLDGLDYQSLHKDVDDVLAKAAARDVKFCLAVATTL
                     PGYRHMRELVGKRDNVVFSCGVHPLNQDEVYDVEELRLLAAEDDVVAMGETGLDYFYT
                     PETKIRQQASFIHHIQIGRELHKPVIVHTRDARADTLAILREEKVTDCGGVLHCFTED
                     RETAGKLLDLGFYISFSGIVTFRNAEQLRDAARYVPLDRLLVETDSPYLAPVPHRGKE
                     NQPAMVRDVAEYMAVLKGVAVEELAQITTDNFARLFHIDASRLSSIR"
     gene            16906..18339
                     /gene="ptsG"
                     /locus_tag="OPV72_001630"
     CDS             16906..18339
                     /gene="ptsG"
                     /locus_tag="OPV72_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIBC"
                     /protein_id="HCR9913972.1"
                     /translation="MFKNAFTNLQKAGKSLMLPVSVLPIAGILLGVGSANFSWLPAVV
                     SHVMAEAGGSVFANMPLIFAIGVALGFTNNDGVSALAAVVAYGIMVKTMAVVAPLVLH
                     LPAEEIAAKHLADTGVLGGIISGAIAAYMFNRFYRIKLPEYLGFFAGKRFVPIISGLA
                     AIFTGVVLSFVWPPVGTAIQAFSQWAAYQNPVVAFGIYGFIERCLVPFGLHHIWNVPF
                     QMQIGEYTNAAGQVFHGDIPRYMAGDPTAGMLSGGFLFKMYGLPAAAIAIWHSAKPEN
                     RAKVGGIMISAALTSFLTGITEPIEFSFMFVAPILYIIHAILAGLAFPICILLGMRDG
                     TSFSHGLIDFIVLSGNSSKLWLFPIVGAGYAIVYYTVFRVLIKALDLKTPGREDSTDD
                     AKAGATSEMAPALIAAFGGKENITNLDACITRLRVSVADVAKVDQAGLKKLGAAGVVV
                     AGSGVQAIFGTKSDNLKTEMDEYIRNS"
     gene            complement(18424..20599)
                     /gene="fhuE"
                     /locus_tag="OPV72_001631"
                     /pseudo
     CDS             complement(18424..20599)
                     /gene="fhuE"
                     /locus_tag="OPV72_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460174.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ferric-rhodotorulic acid/ferric-coprogen
                     receptor FhuE"
     gene            20941..21300
                     /gene="hinT"
                     /locus_tag="OPV72_001632"
     CDS             20941..21300
                     /gene="hinT"
                     /locus_tag="OPV72_001632"
                     /EC_number="3.9.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine nucleoside phosphoramidase"
                     /protein_id="HCR9913973.1"
                     /translation="MAEETIFSKIIRREIPSDIVYQDELVTAFRDISPQAPTHILIIP
                     NILIPTVNDVTAEHEQALGRMITVAAKIAEQEGIAEDGYRLIMNTNRHGGQEVYHIHM
                     HLLGGRPLGPMLAHKGL"
     gene            21303..21677
                     /locus_tag="OPV72_001633"
     CDS             21303..21677
                     /locus_tag="OPV72_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcfL family protein"
                     /protein_id="HCR9913974.1"
                     /translation="MIKGCIAVSLGLLLLTGCRSHPEIPVSDAQSLVMESAVLAAGVT
                     AEPPELTASDIQPSASSRVYNERQEPITVHYRFYWYDARGLEMHPLEAPRSVTIPARS
                     SVTLFGSANYLGAHKVRLYLYL"
     gene            21691..22329
                     /gene="lpoB"
                     /locus_tag="OPV72_001634"
     CDS             21691..22329
                     /gene="lpoB"
                     /locus_tag="OPV72_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein activator LpoB"
                     /protein_id="HCR9913975.1"
                     /translation="MTKMHRYAAIAALAIFLSGCMAQRQPAPVEEVKPAPEQPAQPPQ
                     PPVVPSVPTIPQQPGPIEHEDQTGQPAPKVRHYDWNGAMQPLVSKMLQADGVTARSVL
                     LVDSVNNRTNGSLNANEATETLRNALANNGKFTLVSVQQLAMAKQQLGLSPQDSLGTR
                     SKAIGIARNVGAQYVLYSSASGNVNAPALQMQLMLVQTGEIIWSGKGAVQQQ"
     gene            22310..23134
                     /gene="thiK"
                     /locus_tag="OPV72_001635"
     CDS             22310..23134
                     /gene="thiK"
                     /locus_tag="OPV72_001635"
                     /EC_number="2.7.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine kinase"
                     /protein_id="HCR9913976.1"
                     /translation="MRSNNNNPLTRDEILSRYFPQYRPAVAASQGLSGGSCIIAHDTH
                     RIVLRRHHDPDAPPAHFLRHHRALSQLPASLAPRALFYTPGWMAVEYLHGVVNSALPD
                     ADELAALLYHLHQQPRFGWRIALSPLLAQYWSCCDPARRTPFWLRRLKQLQKNGEPRP
                     LRLAPLHMDVHGDNIVLTSAGLRLIDWEYAGDGDIALELAAVWVEDERQHRQLADAYA
                     ARARIDARQLWRQIRLWHPWVIMLKAGWFEYRWRQTGEQQFIRLADETWRQLRMKG"
     gene            23145..24170
                     /gene="nagZ"
                     /locus_tag="OPV72_001636"
     CDS             23145..24170
                     /gene="nagZ"
                     /locus_tag="OPV72_001636"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HCR9913977.1"
                     /translation="MGPVMLNVEGCELDAEEREILAHPLVGGLILFTRNYHDPEQLRE
                     LVRQIRAASRNHLVVAVDQEGGRVQRFREGFTRLPAAQSFFALHGLEEGGRLAQEAGW
                     LMASEMIAMDIDISFAPVLDVGHISAAIGERSYHADPAKALAMATRFIDGMHDAGMKT
                     TGKHFPGHGAVTADSHKETPCDPRPETDIRGKDMSVFRALISENKLDAIMPAHVIYRA
                     IDPRPASGSPYWLKTVLRQELGFDGVIFSDDLSMEGAAIMGSYAERAQASLDAGCDMI
                     LVCNNRKGAVSVLDNLSPIKAERVTRLYHKGSFSRRELMDSARWKTASAQLNQLHERW
                     QEEKAGH"
     gene            24195..24737
                     /locus_tag="OPV72_001637"
     CDS             24195..24737
                     /locus_tag="OPV72_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCR9913978.1"
                     /translation="MIIYLHGFDSNSPGNHEKVLQLQFIDPDVRLVSYSTRHPKHDMQ
                     HLLKEVDKMLQLNVDERPLICGVGLGGYWAERIGFLCDIRQVVFNPNLFPYENMEGKI
                     DRPEEYADIATKCVTNFREKNRDRCLVILSRHDEALDSQRSAQALHPFYEIVWDEEQT
                     HKFKNISPHLQRIKAFKTLG"
BASE COUNT         5549 a         6334 c         7060 g         5971 t
ORIGIN      
        1 gaaaaacctc cggctatgcc ggaggatatt tatttagtcg ttattgagtt agtggtcata
       61 ttgtcgcgcc cgtagcgacg ccatccgtac gtattatccc gcccgatctc ataaacgcct
      121 ggagtgacta aaagacgcca tggggtgagg catcgccctg taagaggcat aaaaaaaagc
      181 cgacctggcg gtcggctttg tatcagcatt tacatcattc taccggctgt gggcgtgtcg
      241 ccggggcgct ggcgtgacgt gtggcgctgt gtccgcctgc tgcgccttta ccttcaaagt
      301 ggaaggaagg gcgctgccag tcgctatggt gcggggtttc cggcacatat tccggcgctg
      361 gcgcacgcgt catcggcgcg ctggcgtggt tatgatcgtc aacgcagaca acgtcctgcg
      421 gcttttccac cacctgggcc ggtgcgataa cggtttcttc tgccgtgtgc tccacaacag
      481 ccgcttccgc ttttgtctct tcttctggct cgacaacgac aacatcagct acgttttcag
      541 ccaccgtaat ggacgcgtcg gcggtttctg ctaccggttc ggcgtcagca ataacctctt
      601 gcgcttccgg cgtatcgctt tcggcaatca gttgcggctg ttcatcaacc ggcgcggcaa
      661 tcacttccgg atgcgttgtc tcgaccttga cgacttccgg cgcctgtggt tcggcgacgg
      721 tctgcggctc aacggcaacg ttttctaccg cctgtaccga cgcttgtggt tcgagcgcta
      781 cggtcgcagc gataacctgc ggttcagcga caaccggttg tggcagcgcc agatctgctt
      841 cacgctgctc ttcaacaacc tgcgtttcct gaggacggac aatcgggtag cggatccaga
      901 ctttaccgga cgccatttct ggcgacgcgc aggcgacggt taacggcatc ggcgattgtg
      961 tcgggtagcg ctcgtcacga tagcgacggc gacgctgacc gcttacgcgc aggtggcgcg
     1021 gagaacggcg ggagcgacgc ggcataccgg tattatcgcg aggttctacg ctatcatcct
     1081 gctccggcgc gatatcggca acgacaggta aatcaacttt cgccagctcg gtacgcggcg
     1141 ctggaacggg ctgttcaacg ttttcaaccg ggcgtggttc gtcgacgacg accggcgtgt
     1201 caaccgtttc aaccactgtg ctgttggtaa agcggacttt ctgattaagc tgacgttgct
     1261 tacggcgcgg ctgaacctgc tgaacgcgtt cttcctgctc ggtctcctgg acaggctgtt
     1321 cttcgcggtt aagcgctttt acttcctgct gcgcctggcg tttgtcatca ttgcggcggc
     1381 ggctgcgttc gcgacgcggc gtctgttgct gctcatcgcc ggttttcact ttttccgccg
     1441 tttcctgctg gcgggtatcg cgcgcttccg cattttgctg ctgcgcctgg cgacggttac
     1501 gacgattatc gtcgcggctc tcgccgccgt cacgtctggc acggttatca cgggtgtcgc
     1561 ggcgttcgtt acgatcgcga cggttgttct gtcgtggctt gcgacgatcc tgctgacgct
     1621 ccgctttttc ttccgctttc ggcgcggctg tttcgacggt tttcgtttct tcaccgctga
     1681 acagttgttt cagcgcgtta aggaagcggc taaacagacc cggctgggca ggctgctcgg
     1741 cggcaacatt atcctttttc gccgtggcaa cgctaaccgc cggttcgaca ggcgtcggcg
     1801 ccggaggcac atctggcata gcgaatgtcg ccagcgcagg ctgttccggg cgtttacgct
     1861 cggcgtactc ttcttcagaa ggcagcgcca tcgcttcttc gtgcagcttc ggcagcatgt
     1921 agctcagggt cggcgtttct tcccctttgc gtacgcgtag cacggaatag tgcggcgttt
     1981 ccatctgatc gttcgggacg atgacacagc ggacgccatc ctgacgcgtc tcaatagcgt
     2041 taactgccgt ccgtttttcg ttaagcagat aagaggcgat cggcaccgga acaatggcat
     2101 ggacttcctg cgtattctct ttcagcgctt cttcttcaat caggcgcaga atggacagcg
     2161 acagagattc gttatcgcgc acggtgccgg taccgctaca gcgcggacac acgtgatggc
     2221 tggattcgcc cagcgacggg ctcaggcgct gacgcgacat ttcgagcagg ccgaagcggg
     2281 aaatatggct aatctgaata cgcgcccggt cctgacgcac cgcttcacgc aggcggtttt
     2341 ctaccgcgcg ctggtgacgt accggcgtca tatcgataaa gtcgataacg atcaggccgc
     2401 ccaggtcgcg cagacgcaac tggcgggcaa tctcatcggc cgcttcgaga ttggtgttga
     2461 acgcggtttc ttcgatatcg ccgccgcgag ttgcgcgggc ggagttgata tcgatagcgg
     2521 ttaacgcttc ggtgctgtca atgacgatgg agccgccgga gggcaggcgc acttcacgct
     2581 ggaacgcaga ctcgatctgc gattcgatct ggtaatggct gaacaacggg atttcaccgg
     2641 tgtatagctt aattttgctg ctaaaatccg ggcggcccaa cgcggcgata tgctgacgcg
     2701 ccatttccat cacttttgga ttgtcgatta ggatttcacc gatatcctga cgcagatagt
     2761 cgcgaaacgc gcgtacgatg acgttgcttt cctgatggat caggaacggc gcgggacggc
     2821 tttcagcggc tttctgaatg gcttcccagt gtttcaggcg gaagcttaaa tcccactgca
     2881 acgcttcggc ggatttaccc acgcccgcgg tacgtacgat aagccccatc ccttcaggaa
     2941 gttccaggct ggccaacgct tcttttaact cggtacgatc gtcgccttca atgcgacggg
     3001 agataccacc cgcgcgcggg ttattcggca tcagtaccag gtagctgccc gccagactga
     3061 taaaggtggt taacgccgcg cctttgttgc cgcgctcttc tttatcgatt tgaacaatga
     3121 cttcctggcc ttcgcgtaac acgtctttga tgttcgggcg accatgagcg ctgtagttag
     3181 cggggaaata ttcgcgggca atttctttta acgggaggaa accgtggcgt tctgcgccgt
     3241 aatcaacaaa agccgcttcc aggctcggtt caatacgggt aattttgcct ttatagatgt
     3301 tcgctttttt ctgctcgtgt ccggggcttt ctatatccag atcgtacaga cgctgcccat
     3361 ctacaagggc gacgcgcaac tcttcctgct gagtcgcgtt gattaacatt cttttcatcg
     3421 taacttactc attattctta cgttgacgac taagctgcgg gcatggtgac gccttaccgg
     3481 gcatgaaccg atggcctcgt gactatttcg cgtcgccaac ctcacggtta tcgtcagctc
     3541 aaagaggcgc agagtgtcgg ttgcctgtat ttcatacgga aacacagcgc aattatcagg
     3601 gaagcagcct gggcattact ctccagagaa gatcctatct accggtaagg actgcaaccc
     3661 gcagcccgct aactgtctga aaaatcaata cgtcttacgc cattgctgcg ttgatgatcg
     3721 gtcagacaaa atgggttatt ccgctaaact ttttgtttta acaagtttcg gtgcggaaac
     3781 cgcatcatta ttccactgct aaccttgtta tagcaagatg acttttacca tttatcaccc
     3841 gcttactcac agttttttca ccagcgcgag ccaatcgctt taataaccag caaaaccgca
     3901 gtgaaaaatg ttcatccact ggcgtagacg tctctataag catagaaaaa tgtgtggcgc
     3961 gaatctcaca ggctatttag aatcgccccc catgaaaaca gaaacgccat ccgtaaaaat
     4021 tgttgctatc gccgctgacg aagcggggca acgcattgat aactttttgc gcacccaact
     4081 gaaaggggta ccaaaaagta tgatttatcg catcttgcgt aaaggcgagg tgcgggtgaa
     4141 caaaaaacgc attaaaccgg aatacaaact ggaatcgggc gatgaagtcc gcattccgcc
     4201 ggttcgcgtt gctgagcgcg aagaagaggc tgtgtcgccg catttgcaaa aagtggcggc
     4261 gttggcggac gtcattttgt atgaagacga ccatattctg gtgctgaata agccttccgg
     4321 caccgccgta cacggtggga gcgggttaag tttcggcgtc atcgaagggc tgcgggcgtt
     4381 gcgtccggaa gcgcgattcc tggaactggt gcatcgtctt gaccgcgata cttccggcgt
     4441 gctgttggtg gcgaaaaaac gctccgcgct gcgttcgctg catgagcaac tgcgcgaaaa
     4501 gggaatgcag aaagattatc tggcgctggt gcgcggccag tggcaatcac acgttaaaac
     4561 cgtacaggcg ccattattaa agaacattct gcaaagcggc gaacgcattg tccgcgtgag
     4621 ccaggaaggc aaaccttcag aaacgcgctt caaggtggaa gagcgttatg ccttcgccac
     4681 gctggtgcgc tgtagcccgg tcacgggccg tacgcatcag attcgcgtac atacccaata
     4741 tgccggtcac cctattgcgt tcgacgatcg ctacggcgac cgtgagtttg atcaacagct
     4801 taccgaagcg ggaaccggtc ttaaacgtct ctttctgcac gccgcggcgc tgaagttcac
     4861 gcatccggga acgggcgatg tcatgcgcat tgaagcgcca atggataagc aattgaagcg
     4921 ctgccttgag gtattacgta gtaaagcctg atgcgcgttg cttatcaggc ctacaatcgt
     4981 gtgatgcacc gtaggcctga taagacgcat cgcgtcgcca tcaggcagat taatcaggca
     5041 ttcagcgggt tcatctcttc ccgtcgcagc atctggcaca gggcaataag cggcaagccg
     5101 atcagcgtgt tcggatcgcg gccctctaag cgctcaaata atgcaatgcc taaaccttcg
     5161 cttttaaaac ttcccgcgca gtgcagcgga tgctctttac ggacatagtc gtctatttcc
     5221 gcttcgctta aatggcgaaa gtgaacgtca aaaggctcca cttcggtttg taagtgcccg
     5281 gaggcggagt tatacagtgc cagtccggta taaaacgtca caatacttcc gctggctttg
     5341 gctaattgct gacgcgcttt ttcttccgtc agcggtttgc cggtgatttc gccgtccaga
     5401 acacaaattt ggtcggagcc aataatcaaa tgattcggga aacgcgcggc gagcgattgc
     5461 gccttagcct gcgccagccg cagcaccaac tgacgcggcg cttcgcccgg catgggggtt
     5521 tcatcaacat ccggcgcggc gcattcgaaa ggaatcgtca gcttttccag cagcgcgcga
     5581 cgccagggag aggtagacgc aaggatgaga cggggcatat tttttccctc agatatagcg
     5641 taatgatgag agccatctta aactatgctc ttcggtcttc aagcctgtca tactgactcg
     5701 tcttgagcga aaataagtct gtaacccgca atgtgtgcga attattggca aaaggcaacc
     5761 gcaggctgcc tttttctttg actatatgac gttacgaagt taatatgcgc gccctatgca
     5821 aaaggtaaaa ttacccctga ctcttgatcc ggttcgtacc gctcaaaaac gccttgatta
     5881 ccagggtatc tatacccccg atcaggttga gcgcgttgcc gaatctgtag tcagtgtgga
     5941 cagtgatgtg gaatgctcca tgtcgttcgc tatcgataac cagcgtctcg ccgttttgac
     6001 tggcgatgcg gtcgttacgg tgtcgctcga atgccagcgt tgcgggaaac cgtttaccca
     6061 tcaggttcac acaacgtatt gttttagccc tgtccgttcc gacgagcagg ctgaagcact
     6121 gccggaagcg tatgagccga ttgaggtaaa cgaattcggc gaaatcgatc tgctggcgac
     6181 ggttgaagat gaaatcatcc tcgccttgcc ggtagttccg gtgcatgatt ctgaacactg
     6241 tgaagtgtcc gaggcggaca tggtctttgg cgaactgcct gatgaagcgc aaaagccaaa
     6301 cccatttgcc gtattagcca gcttaaagcg taagtaatag gtcttccccg cggacgcagg
     6361 gataaaccgt aattgaggag taaggtccat ggccgtacaa cagaataaac caacccgttc
     6421 caaacgtggc atgcgtcgtt cccatgacgc tctgaccgca gtcaccagcc tgtctgtaga
     6481 caaaacttct ggtgaaaaac acctgcgtca ccacatcact gccgacggtt actaccgcgg
     6541 ccgtaaggtc atcgctaagt aatcgcgcga tactcgatgc cttttgcatc acaggcgtgc
     6601 ctgtggtgta aaagccgaag agtacaagcg tgataaagct tagtgaggat ttctccgcgt
     6661 aagcggagaa caccgaacca ggcagcgacg ataccttgac acgtctaacc ctggcgttag
     6721 atgtcatggg gggcgatttt ggtccttccg tgacggtgcc tgcagcattg caggcactga
     6781 acgctaattc gcagctcact cttcttttag tcgggaatcc cgatattatc acgccattac
     6841 ttgccaaagc tgactttgaa caacgttcgc gtctgcagat tatccctgca cagtcagtta
     6901 ttgccagtga tgcccggcct tcgcaggcga tccgcgccag tcgcgggaca tccatgcgtg
     6961 tggccttgga gcttgtgaaa gaaggccgag ccgaagcttg cgttagcgcc ggtaataccg
     7021 gggcgctgat ggggctggcg aaattattgc tcaagcctct tgaggggatt gagcgtccgg
     7081 cgttggtgac ggtattaccg caccagcaaa agggcaaaac ggtagtgctt gatttggggg
     7141 ccaacgtcga ttgcgacagt accatgctgg tgcagtttgc cgtgatgggc gccgttttgg
     7201 cggaagaggt cgtcgggatc aaaaatcccc gcgtggcgct actcaatatc ggggaagaag
     7261 aaaccaaagg cctcgacagt attcgcgaag cctctttaat gttaaaaaca gtcccaacca
     7321 tcaattacat cggctacctt gaggcgaatg agttactgac gggaaaaacc gatgtactgg
     7381 tgtgtgacgg ctttacaggc aatgtcacgc ttaaaacgat ggagggggtt gtcagaatgt
     7441 tcctttcact gctgaaatca cagggcgagg ggaaaaaacg gtcgtggtgg ctgctgttat
     7501 taaaacgttg gttacaaaaa agcctgacga ggcgattcag tcacctcaac cccgaccagt
     7561 ataatggcgc ctgtctgtta ggattgcgcg gcacggtgat aaaaagtcat ggtgcggcca
     7621 atcagcgagc atttgcagtc gcgattgaac aggcagtgca ggcggtgcag cgacaagttc
     7681 ctcagcgaat tgccgctcgc ctggaatctg tatacccagc cggatttgaa ccgctggacg
     7741 atggcaaagg cgtaaacctg cgggcgcaca gataatatcg ctgtctcccc ggcgccgcca
     7801 gcgtgccaga cgtttacagg taacggtata taaccgaaaa gtgactgagc gtacatgtat
     7861 acgaagatta ttggtactgg cagctatctg cccgaacaag tgcggactaa cgccgatttg
     7921 gaaaaaatgg ttgagacctc tgacgagtgg attgtcactc gtacaggtat tcgtgaacgc
     7981 catatcgccg cgccgaatga aactgtcgcg acgatgggct ttaccgctgc gaatcgcgcg
     8041 attgagatgg cggggatcga taaagaccaa attggcttga ttgtggtagc gaccacatca
     8101 gcaacgcatg catttccaag cgcggcatgt cagattcaaa gtatgctcgg tattaaaggt
     8161 tgcccggcgt ttgatgtcgc ggcagcgtgc gcaggtttca cctacgcgtt aagtatcgcc
     8221 gaccagtacg ttaaatccgg cgtggttaaa cacgcgctgg tggtcggttc cgatgtatta
     8281 gcccgcactt gcgatcctgg cgatcgcggt acgatcatta ttttcggcga tggcgcaggc
     8341 gcggccgtac tgagcgcttc tgaagaaccg ggtattatct ccactcatct tcatgccgat
     8401 ggccgttacg gtgaattact gaccctgccg aatgccgatc gtgtaaatcc ggataacccg
     8461 atttacctga cgatggcggg taatgaagtc tttaaagtgg cggtcactga actggcgcat
     8521 attgtcgatg agacgctggc ggctaataac ctggatcgct cagaactcga ttggctggtg
     8581 ccgcatcagg ctaacctgcg tatcattagc gcgacagcga aaaaactcgg catgtcgatg
     8641 gacaatgtcg tcgtcacgct ggacaggcac ggcaatacct ccgcggcttc tgtgccgtgc
     8701 gcgctggatg aagccgtgcg tgacgggcga attaaagccg gtcagctggt attgcttgaa
     8761 gccttcgggg gtggattcac ctggggctcc gcgctgattc gtttctagta taaggattta
     8821 aacatgacgc aatttgcatt tgtgttcccc ggtcagggtt ctcagagcgt tgggatgttg
     8881 gccgagatgg cggcaaatta ccctatcgta gaagaaacgt ttgctgaagc ttctgcggct
     8941 ctgggatatg atctgtgggc gctcacccag caaggtccag cggaagaact gaataaaact
     9001 tggcagacgc agccggcgct attaaccgct tccgtcgcgc tttggcgcgt ttggcagcag
     9061 cagggcggta aaatgcctgc gttaatggca ggtcacagcc tgggcgaata ttccgcgctg
     9121 gtttgcgctg gcgtcatcaa ctttgctgat gccgttcgtc tggtggaaat gcgcggtaaa
     9181 ttcatgcagg aagcggttcc ggaaggtact ggcggcatgt ctgcgatcat cggtctggat
     9241 gatgcctcta ttgctaaagc ctgtgaagaa tctgccgaag ggcaggttgt ttcgccggtt
     9301 aactttaact cgccgggaca ggtggttatc gccgggcata aagaggcggt agaacgcgcg
     9361 ggcgcagcct gtaaagccgc tggcgcgaaa cgcgcgctgc cgctgccggt gagcgtgccg
     9421 tcgcactgcg cgctgatgaa accaacggca gataagctgg cggttgaatt agccaaaatt
     9481 acctttagcg cgccaacggt gccggtagta aacaacgttg acgtgaaatg tgaaaccgat
     9541 gccgccgcta tccgcgatgc gctggttcgc cagttgtaca atccggtaca gtggacgaag
     9601 agcgtggaat ttatcgcggc gcagggcgtt gaacatcttt atgaagtggg tccaggtaaa
     9661 gtcctcactg gtctgacgaa acgtattgtc gacaccctga cagcgtcggc gctgaacgag
     9721 ccggcggcgc tgtctgcggc acttacgcaa taaaagagga aaaccatgag ctttgaagga
     9781 aagattgcgc tggtgactgg tgcaagccgt ggcataggcc gcgcaattgc agagactctc
     9841 gttgcccgcg gcgcgaaagt tatcgggact gcgaccagtg aaaatggtgc gaagaacatt
     9901 agcgactatt taggtgctaa cgggaaaggt ttgatgttga atgtgaccga tcctgcatct
     9961 attgaatctg ttctggaaaa tattcgcgca gaatttggtg aagtggatat cctggttaat
    10021 aatgccggta tcactcgtga taatctgttg atgcgaatga aagatgatga gtggaacgat
    10081 attatcgaaa ccaatttatc atccgttttc cgcctgtcaa aagcggtaat gcgcgctatg
    10141 atgaaaaagc gttgtggtcg cattatcact attggttctg tggttggtac catgggaaat
    10201 gcaggtcagg caaactacgc tgcggcgaaa gcgggcctga tcggtttcag taaatcactg
    10261 gcgcgtgaag ttgcgtcccg tggtattact gtcaatgttg tggctccggg ttttattgaa
    10321 acggacatga cgcgtgcgct gtctgacgat cagcgtgcgg gtatcctggc gcaggtgcct
    10381 gcgggtcgcc tcggcggcgc tcaggaaatc gccagtgcgg ttgcattttt agcctctgac
    10441 gaagcgagtt acatcactgg tgagactctg cacgtcaacg gcggaatgta catggtttaa
    10501 tcacgattga aaaatatttg cgttattagg gcgaaaggcc gcaaaataac gtaaaatcgt
    10561 ggtaagacct gccgggattt agttgcaaat ttttcaacat tttatacact acgaaaacca
    10621 tcgcgaaagc gagttttgat aggaaattta agagtatgag cactatcgaa gaacgcgtta
    10681 agaaaattat cggcgaacag ctgggcgtta agcaggaaga agtaaccaac aatgcttctt
    10741 tcgttgaaga cctgggcgca gattctcttg acaccgttga gctggtaatg gctctggaag
    10801 aagagtttga tactgagatt ccggacgaag aagctgagaa aatcaccacc gttcaggctg
    10861 ccattgatta catcaacggc caccaggcgt aagtgaacat ctccaggcgg tcgttcgacc
    10921 gcctgagttt tatctttttg tcccactaga atcattttcc ctccctggag gacaaccgtg
    10981 tctaagcgtc gtgtagttgt gaccggactt ggcatgttgt ctcctgtcgg caataccgta
    11041 gagtctacct ggaaagctct ccttgccggt cagagtggca tcagcctgat cgaccatttc
    11101 gatactagcg cctatgcaac gaaatttgct ggcttagtaa aggattttaa ctgtgatgac
    11161 attatctcgc gcaaagaaca gcgcaagatg gatgccttca ttcaatatgg aattgtcgct
    11221 ggcgtacagg ccatgcagga ttctggcctt gaagtgacgg aagagaacgc aagccgtatt
    11281 ggcgccgcta tcggctccgg tatcggtggt ctcggtctga tcgaagaaaa ccacagttcg
    11341 ctggtaaaag gcggaccgcg taagattagc ccgttctttg tcccgtcgac gattgttaac
    11401 atggtagcag gccatctgac tatcatgtat ggcctgcgtg ggccaagcat ctctattgcg
    11461 actgcctgta cttcaggcgt gcataacatc ggccatgccg cgcgtatcat cgcctatggt
    11521 gatgcggacg cgatggtggc aggtggcgca gaaaaagcca gtacgccgct gggcgtaggt
    11581 ggttttggcg cagcgcgcgc gctgtcgacc cgcaacgata acccacaggc ggcgagccgt
    11641 ccgtgggata aagaacgcga tggttttgta ctgggcgacg gtgccggtat gttggtgctt
    11701 gaagagtacg aacatgcaaa agcgcgtagt gcgaaaatct atgctgaaat cgtcggcttt
    11761 ggtatgagca gcgatgctta ccatatgacg tcgccgccgg aaaatggcgc aggcgctgcg
    11821 ctggcgatgg ttaacgcgtt gcgtgatgcc gcgattgagc ctgctcagat tggctacgtc
    11881 aacgcgcacg gcacgtcgac gcctgccggc gacaaagctg agacgcaggc ggttaagtca
    11941 gtctttggcg atgctgcaag ccgagtgatg gtgagctcga ccaaatcgat gaccggccat
    12001 ctgttgggcg ccgcaggcgc agtagagtct attttctcta ttctggcgct acgcgatcag
    12061 gccattccgc caaccattaa tctggataac ccggatgaag gttgcgatct ggacttcgtg
    12121 ccgcatgaag cgcgccaggt cagcgatctg gagtacgcgc tgtgtaactc ctttggcttt
    12181 ggcggaacta acggttcctt gatctttaaa aagatctaag ttaagccaga gacagacatt
    12241 aataaaaagg tccgcttgtc gggccttttt tatcaggcat atcacctctt gttctgcgtt
    12301 attcatcctg ccacactagc aggcgacgga taaggagcca ctatgttttt aattaatggc
    12361 catgcgcagg atcaacttgc tgtaagcgac cgggcgacgc agttcggcga tggcagtttt
    12421 acgaccgcac gtattgttga tggcaacatt tgccatctgg aagcgcatct tcagcgcttg
    12481 caggttgcct gtgaaaaatt acggatcgct tttagccatt ggtcgaccct tcggcaagag
    12541 atgacaatgt tggccacagg gcatgattca ggcgtgttga aagtgatcat tagccgtggt
    12601 agcggcggcc ggggatacag cgccatgaat tgtcaggcag ctacccgaat cctctccgtt
    12661 tctgcttatc ccgcttatta ttctcagtgg cgtaagcaag gcatcactct tacccttagt
    12721 cccataccgc ttgggcgcaa tccttatctt gccggattaa aacatctgaa ccgcctcgaa
    12781 caggtgttga ttcgctctca tcttgagcag acggacgccg atgaggcgct ggttcttgac
    12841 agcgagggat gggttacgga atgctgtgcg gctaatttgt tctggcgtac aggcgacatt
    12901 gtttttacgc cgcgtctgga tcaggccggg gtgaacggca ttatgcgaca attttgttta
    12961 cgccaactgg cgcaatctcc tttccaggtt cttgaagtac aggcgagaga ggaggcagtc
    13021 aggcaggcgg atgagattat catctgcaac gcgctaatgc cgattattcc catacgcgcc
    13081 tatcacggga cgtcgtattc ttcgcgaaca ctgtttcaat ttttagcccc attttgtgag
    13141 catccgaatt agttatgaaa aaattgtcag gcgttttcct tctgctgttg gttgtgctgg
    13201 gtattgccac gggcgtgggg atgtggaaag ttcgccatct ggcgaacagc acgttactta
    13261 ttaaaaacga gactatcttt acgctcaagg cgggaacggg tcggctggcg cttggtgacc
    13321 agctttatga tgaaaaaatc attaatcgtc cccgggtatt tcagtggctg ctgcgcgtgg
    13381 agcctgagtt atcgcacttt aaagcgggaa cttaccgttt tacgcccggg atgaccgtac
    13441 gggagatgct tgagttgctg gagagcggca aagaagcgca attcccgttg cggtttgtgg
    13501 aagggatgcg ccttagcgat tacctgaaac agttacgaga ggcgccgtat attcgccata
    13561 cattgccgga tgatgactac gccactgtcg ctcaggcatt aaagcttgcg cacccggaat
    13621 gggtagaagg gtggttctgg cctgatacct ggatgtatac cgccaacacc agcgatgtcg
    13681 ctattctcaa gcgagcgcac caaaagatgg tgaaagctgt cgatactgtc tggaaaggtc
    13741 gggccgaggg gctgccttat aaagatcaga accaactggt gacaatggcc tcgattattg
    13801 aaaaagagac ggctgtcgcc agcgaacgcg atcaggtggc ctcagtcttt attaatcgcc
    13861 tgagaatcgg tatgcgcctt cagaccgatc ccaccgtgat ttacgggatg gggacgagtt
    13921 ataatggtaa cttgtcgcgt gcggatctgg aaaagccgac ggcttataac acgtatacca
    13981 taaccgggct gccgccagga ccgattgcat cgcccagcga agcgtcattg caggcggcgg
    14041 cgcatccggc gaaaacgccg tatctctatt ttgtggccga cggtaaaggc ggtcacacat
    14101 ttaacaccaa tcttgccagc cataatcggt cagtgcagga gaaagtgctt aaggaaaaaa
    14161 atgggcagta attatatcgt catcgagggc ctggaaggcg ccggaaaaac cactgcgcgc
    14221 gacgtggtgg tggagaccct tgagcaactg ggtattcgta acatgatttt tacccgtgag
    14281 ccgggcggta cgcagcttgc cgaaaaacta agaagtctgg tgctggatat ccgatcggta
    14341 ggcgacgaag tgattaccga taaagcggaa gtgctgatgt tttatgccgc tcgcgtacag
    14401 ctcgtcgaaa cggtaatcaa acccgcgctg gcgcaaggcg tatgggtgat cggcgatcgc
    14461 cacgatctct cgacccaggc gtatcagggg ggagggcgcg gcattgatca aaccatgctg
    14521 gcgacactac gcgatgccgt gctgggcgat tttcgtcctg acctgacgct gtatctggat
    14581 gtcacgccgg aagtcgggct aaaacgcgcc agagcgcgcg gcgatttgga tcgcattgag
    14641 caggaatctt ttgatttctt taaccggact cgcgcgcgct atctggaact ggcggcgcaa
    14701 gactcgcgta tccgcaccat tgacgcgacc cagccgctgg atgccgtcat gcgcgacatt
    14761 cgcgccacgg tgacgaagtg ggtgcaggag caagcggcat gaaatggtat ccatggttac
    14821 ggcccgccta tgaaaaactg gtagaaagtt accaggcggg acgtgggcac catgcgctac
    14881 tgattcaggc cttacctggc atgggcgacg aggcgctgtg ctatgcgctg agccgttatc
    14941 tgttatgcca gcagcctgag ggccacaaaa gctgtgggca ttgccgtggc tgtcagctta
    15001 tgcaggctgg cacgcatccg gactattaca cgctgacgcc ggataaaggc aaaagcagcc
    15061 ttggtgtaga tgcggtacgc gaggtcagcg agaaattgta cgagcactcc cgtctgggtg
    15121 gtgcgaaggt ggtgtggatt gcggatgcgg cgctattaac cgacgccgcc gccaatgcgt
    15181 tgctcaaaac gctggaagag ccgccggagc aaacctggtt tttccttgcc agcccggagc
    15241 ctgctcgtct gttggcgaca ttacgcagcc gttgtcggct gcatcatctg gcgccgccgt
    15301 ccgaatcgta tgcgatgtca tggctgtcgc gagaagtgac ggcgtcacaa gaagcattgc
    15361 tcacggcgct acgcctgaac gcggggtcgc ccggcgccgc gctggcgctg ttgcagtctg
    15421 aacgttgggc gcagcgtgag gcgctgtgtc aggcgttgat ggacagttta catacgggcg
    15481 actggtatgc gttattaacg gcgctcaatc atgagcaagc cccggcgcgc ctgcactggc
    15541 tggcgacgct gctggtagac gcgctgaaac gtcagcacgg cgcgtcgtac ctgacaaacg
    15601 ttgatgcgga cgcggttgtt gccgcgctgg cggggccgct atccccggcg cgtattcagg
    15661 caatcctgaa cgatgtttgc cattgtcgtg atcaattact tcatgtgacc ggattaaatc
    15721 gcgaactggt attaaccgat ctcattctcc gcatcgagca ttacctgcaa ccaggcacct
    15781 tgttgcctgt tcctcatctt tgagagagac attatgtttt tagtcgactc acactgccat
    15841 cttgatggtc tggattatca atctttgcat aaggacgtgg acgatgtgct ggcgaaagcc
    15901 gccgcgcgcg atgtgaagtt ctgtttagcg gtggcgacga cgttgccggg gtatcgccat
    15961 atgcgcgagc tggtgggcaa gcgcgataat gtggtctttt cctgcggcgt gcatccgtta
    16021 aatcaggatg aagtatatga cgtagaagaa ctgcgcctcc ttgctgcaga agacgatgtg
    16081 gtggcgatgg gcgagaccgg gcttgattac ttttacacgc ctgagaccaa aatccgccag
    16141 caggcgtctt ttattcatca tatccagatt ggccgcgaat tgcataaacc ggtgattgtc
    16201 catactcgcg acgcgcgtgc cgatacgctg gctatcctgc gcgaagaaaa agtgacggat
    16261 tgcggcggcg tactacactg ttttacagaa gacagagaaa cggccggcaa attgctggat
    16321 ctggggtttt atatctcttt ttccggcatc gtaacgttcc gtaacgctga acagttgcgt
    16381 gatgcggcgc gctatgtgcc gctggatcgg ttattagtcg agaccgattc tccttatctg
    16441 gcgccggtgc cgcatcgcgg taaagagaac cagcctgcga tggtacgcga cgtcgcagaa
    16501 tatatggcgg tattgaaagg ggttgccgtt gaagaactgg cgcagatcac caccgataac
    16561 tttgctcgcc tgttccatat tgacgcgtct cgcctgtcat caatccgtta aacgagtttt
    16621 tttaaagctc gtaattaata agcaaagcgc gtaaagttca ccgccacaaa aggggcggtg
    16681 agcgagctta tggaaacatt cgaaaactca ttttggcaga atgtgatact ttttaggcta
    16741 tctggcgctg aaacgtgata gccgtcaaac aaaatcagac gtatttattt tactctgtgt
    16801 aataaataaa agggcactta gatgtcctgt ccacggcggg gttctccccc ctcgccaatg
    16861 cgtgagaacg tagaaaagca caaatactca ggagcactct caattatgtt taagaatgca
    16921 tttactaacc tgcaaaaggc cggtaaatcg ctgatgctgc cggtatccgt actccctatc
    16981 gcaggtatcc tgctgggtgt cggttccgct aacttcagct ggctgccagc cgttgtatcg
    17041 cacgttatgg cagaagcggg cggatctgtt tttgccaata tgccgctgat tttcgctatc
    17101 ggcgtggcgt tgggcttcac caacaacgac ggcgtttcgg ctctggcggc ggtagtagcg
    17161 tatggcatca tggtgaaaac catggctgtg gttgcgccgc tggttctgca tttacctgct
    17221 gaagagatcg ccgctaaaca ccttgctgat acgggtgttc tcggggggat tatctccggt
    17281 gcgatcgcag cgtatatgtt taaccgcttc taccgtatca aactgcctga gtatctgggc
    17341 ttctttgcgg gcaaacgctt cgtgccgatc atttcgggtc tggccgctat ttttaccggt
    17401 gtggtgctgt ctttcgtatg gccgccagtc ggtacggcta tccaggcgtt ctcgcagtgg
    17461 gcggcttatc agaacccggt tgtcgcgttt ggcatttacg gttttatcga gcgttgcctg
    17521 gtgccgtttg gtctgcatca tatctggaac gttcctttcc agatgcagat cggcgaatac
    17581 accaacgcag cgggtcaggt attccacggc gacattccgc gctatatggc gggcgacccg
    17641 acggcgggta tgttgtctgg cggcttcctg ttcaaaatgt acggtctgcc ggctgcggcc
    17701 attgctatct ggcactctgc taaaccggaa aaccgcgcaa aagtgggcgg tatcatgatt
    17761 tccgccgcgc tgacctcgtt tttgacgggt attaccgagc ctatcgagtt ctccttcatg
    17821 ttcgtggcgc cgatcctgta cattattcac gcgattctgg caggtctggc attcccgatc
    17881 tgtatcctgc tggggatgcg tgacggtacg tcgttctccc acggtctgat cgactttatc
    17941 gtgctgtccg gtaacagcag caaattgtgg ctgttcccga ttgttggcgc cggttatgcg
    18001 attgtgtact acaccgtgtt ccgcgtgctg atcaaagcgc tggatctgaa aacgccgggc
    18061 cgtgaagact ctactgatga cgcaaaagcg ggcgctacca gcgaaatggc gccggctttg
    18121 attgcggcgt ttggcggtaa agagaacatc actaacctgg atgcctgtat cacgcgtctg
    18181 cgcgtgagcg tagccgatgt agcgaaagtg gatcaggctg gcctgaagaa actgggcgcg
    18241 gcaggcgttg tcgtcgcggg ttccggcgtt caggctattt tcggtacgaa atccgataac
    18301 ctgaaaacgg aaatggatga gtacatccgt aacagctaag cagtaatgat gttggggagt
    18361 attaaggcag ccattcggct gcctttttta atggcgcttt acatgacgct ctccgacagt
    18421 ctgtcagaac tgatagttgg cggtgaggct gacgttacgc ggcgcgccgt aaacaatgga
    18481 actatcaata ttggtgtcgt aggttttatc gaacaggttg ttgatgtttc cctgtacgga
    18541 gaaatttttc gtcacctgat agcgggtaaa cagatcgacc agcgcatagc tgccctgttc
    18601 ggcgcggaag gtgccgtatg gcgtcgtggt atctttgtaa acccgattct gccagttcac
    18661 gccgccgccg accgtcagct ccggtatcgc cggcagacga tagcgggtga ataacttcac
    18721 gctggtgcgc gggagattag ggttcacggc gttaccttca ttgtcctcgg caacataccg
    18781 ggtagccccg aaagtcatct gccagttatc ggtaattgcg ccgttcactt caaattcgac
    18841 gcctttgctc accgttccgt cagtagactt ccaggcaaat tccccattac tgccagggat
    18901 gggaatagtg gttgcttgag cgacattatc ctgctcaatg cggaacacgg acaacgtagt
    18961 ggtgaggcgg ctgttcatcc agtcggactt caggcccgct tcatagttat taccggtaat
    19021 cggagccaga tattgacccg ctttgtcgcg tttattctgc ggctgaaaga tagaggtata
    19081 actggcataa gcggaccagt tgtcgttgat atcataaatc agcccggcat acggcgtggt
    19141 atggtttttc tccatgctgt aggtcagtgt atcaacacgc cagttggtat aacgagcgcc
    19201 aagaatcaga tgcagcgggt cggccagcga aatgcacgta gcggcataca gcgatttcat
    19261 atgcgtggta tcgtcctgcg ccagattttg tggcgcccag tgggtttggg ggaaattacc
    19321 gttaaaggcg ccgaagttgc caatgtcgtc cggaaagacg ttcgcccagg cgctaaaata
    19381 gcggttattc tgtttactat aactgccgcc aaacatcata ttgtgctgac ggccaaacag
    19441 ctcataagcg ccatcagcaa agagatctat ggcatctact ttgcgcttgc cgctgttcca
    19501 gccagtaccg ccgaccacgg ggtagcttgc gccataagga ctcaccagcg tacctgtctc
    19561 tttatccact aaagcatcga tatacatcat tttactgtcg aatttgaccc tcagtatggg
    19621 tcgcattcag ggtcgcctgc cagctttcgg caaaacgctg cttaagcgtg acgaagaatt
    19681 tatttatctc tttattgtta taagcccagt ccggggcggt actacgcgcg cggtcatagc
    19741 tatttttgct gccatcggta ttccagcgcg gcagaccgcc ccaggtcggg ctgttgacat
    19801 caattttttg atattcataa ccggctgaaa ggttggtagt tgcacccaga tcggcatcga
    19861 taattccgga aaagaacgct ttctcactgt tatagcggtc cagccaggaa tcattattct
    19921 gataacccgc cacgatgcgc ccacggacat taccgtctgc ggtgagcgga ctttgcagat
    19981 ccatgacgta acgctgctta ttccagctac cgtattctgt ggagacgtta cctttgaact
    20041 cccgactggt ggcgtgttta cggatcatat taattgaggc agaaggattg ccggttccgg
    20101 tcatcagccc attcgcgccg cgaaccacct ccacgcgctc atacagcgcg gtatccgtta
    20161 gcgcatcgcc cagattccag cgggactcaa aatacgttgg aataccgtca accatatagt
    20221 tgtcaatttc aaacccgcgc gagtaatagc tgatgcgatc ggagtcagcc tggcttccgc
    20281 tgatccccag cgtattggtc atcacctcgc ccagggtttg caactgctgg tcttccatac
    20341 gctgttggct gacaatactg accgactgcg ggatatcgcg ctgagtcatc ggcattttgg
    20401 tgcccgctgc ggtcgttttc acgctgtaat cctgttcttc acggtttatg gcgtcagcgg
    20461 tcgtcgcgcc ttcgacaata acggtatcct cagccgcgaa ggcggcaggc ataaatgcca
    20521 tcgccatacc catagctaac agcgacggtg cggcggtgga cggaaggtgt ttgtcccggc
    20581 ggtattgaat gaaagacatc tgaaaatcct tgcttgttat tggggtaagt tcaggacgta
    20641 tgacgttgaa ccttttcatt ctttgctagt taatgcgtat aaaaatgcaa atgagaaata
    20701 tacgcatttg tattaaatgt gtaaaacggt ataaccaggg aaactagaaa tattttttaa
    20761 gcgtacaaag gcgtcatggc agggggatat ggcggtaagt ccagcatgta gtcatttttc
    20821 gcttaataaa tcgtgggtta aagttgaaag agcgtcggta actcgctcat actctatact
    20881 cgcagtatgg ctcggcgtag catgtgcgct gcaagggcta ttatgaaaaa ggaaaacgtc
    20941 gtggcagaag aaactatatt cagcaaaatt attcgtcgtg aaatcccttc ggatatcgtt
    21001 tatcaggatg agctggtcac cgcctttcgt gatatttcac cgcaggcgcc gacgcatatc
    21061 ttgattattc ccaatatcct gatcccaacc gtcaatgacg tgacggcgga acatgaacag
    21121 gcgttaggtc ggatgatcac cgtggcggcg aaaatcgctg aacaagaagg cattgccgaa
    21181 gatgggtatc gtttaatcat gaataccaac cgtcatgggg gccaggaggt ttatcatatc
    21241 catatgcacc tactgggcgg ccgcccgcta ggcccgatgc tggcgcataa aggcttgtaa
    21301 gtatgatcaa aggatgcatc gcggtttctc tgggcttgct gctgcttacc ggctgccggt
    21361 cacatcctga aattccggta agcgacgcgc agtcgctggt gatggagtcc gcggttctgg
    21421 cggcgggtgt caccgcagag ccgcctgaac tgacggcgtc tgatatccag ccatcagctt
    21481 cttcccgcgt ctataacgaa aggcaagagc ccataaccgt tcattatcgg ttttactggt
    21541 atgacgcgcg ggggctggag atgcatccgc tggaggcgcc gcgtagcgta accatacccg
    21601 cgcgttcgtc ggtaacgcta tttggcagcg ccaattatct gggggcgcat aaggtcaggc
    21661 tttatcttta tttgtgagga gtgaattttg atgacaaaaa tgcatcgcta cgccgccatt
    21721 gctgcgctgg cgatatttct ctccgggtgt atggcgcaac gtcaacctgc gccagttgaa
    21781 gaggtaaaac cagcgccaga acaacccgcg cagccgccgc agcctcctgt tgtgccgtct
    21841 gtgccaacga ttccacaaca accggggccg atcgaacatg aagatcaaac gggccagcca
    21901 gcgcctaagg tgcgccacta tgactggaac ggcgcgatgc aaccgctggt cagcaaaatg
    21961 ttgcaggctg atggcgtgac ggccagaagc gtattgcttg tcgacagcgt gaataaccgg
    22021 acgaatgggt cgttaaatgc gaacgaggca acggaaacgt tacgtaatgc gctggcgaac
    22081 aacggtaaat ttacgctggt ctccgtacag caactcgcga tggcaaaaca gcagttaggg
    22141 ttgtctccgc aggatagtct gggaacgcgc agtaaagcta ttggcattgc gcgcaatgtc
    22201 ggggcgcaat atgtacttta ctccagcgca tccggtaacg ttaacgcgcc tgcattacag
    22261 atgcagttaa tgctggtgca aactggcgag ataatctggt caggtaaagg tgcggtccaa
    22321 caacaataat cccttaacgc gcgacgagat cctgtcgcgc tattttcccc agtatcgtcc
    22381 cgccgtcgcc gcatcgcagg ggctaagcgg cgggagctgt attattgctc acgatactca
    22441 ccgtatcgtg ctgcgccgtc atcacgaccc cgacgctcca ccagcccatt ttttacgtca
    22501 tcaccgcgcc ttatcccaat tgccggccag tctggcgccg cgagcgcttt tttatacgcc
    22561 aggctggatg gcggtagaat atctgcatgg tgtggtaaat tccgctctgc cagatgccga
    22621 cgaactggcg gccttactgt atcatttgca tcaacagccg cgttttggct ggcgtatcgc
    22681 gctatcgcca ctattggcgc agtactggtc gtgttgcgat ccggcaaggc gtacgccgtt
    22741 ttggttgcgg cggctcaaac agttgcaaaa aaacggtgaa cctcgcccgc tgcggctcgc
    22801 gcctttgcat atggatgtcc atggcgacaa tatagtatta acgtccgccg ggttgagact
    22861 gattgactgg gagtatgccg gcgacggcga tattgcgttg gagctggcgg cagtatgggt
    22921 tgaggatgaa cgccagcacc gacaactggc agacgcttat gccgcgcgcg cgcgaatcga
    22981 cgcccggcag ctatggcgac agatacgatt atggcacccc tgggtcatta tgctaaaagc
    23041 agggtggttc gaataccgct ggcgacaaac cggcgagcaa caatttatca ggctggccga
    23101 tgaaacctgg cgccagctac gtatgaaagg ataaggagag cagtgtgggc ccagtaatgt
    23161 tgaatgtcga aggatgtgag ctggatgcgg aggagcgcga gatactggcg catccgctgg
    23221 ttggcgggct tattctgttc acgcgtaatt accatgaccc ggaacagctg cgcgaattag
    23281 tgcgccagat tcgggcggca tcgcgtaacc atctggtggt ggccgtcgat caggaaggcg
    23341 ggcgcgtaca gcgtttccgt gaagggttta cccgcctgcc cgcggcgcaa tctttttttg
    23401 cgctgcatgg gctggaagag ggggggcgac tggcgcagga ggcagggtgg ctgatggcca
    23461 gcgaaatgat cgcgatggat attgatatca gttttgcgcc agtgctggac gttgggcata
    23521 tcagcgcggc aattggcgag cgttcttatc atgccgatcc cgcaaaagcg ttggcaatgg
    23581 caacacgctt tattgacggc atgcatgacg ccgggatgaa aacgaccggt aagcatttcc
    23641 ccggccacgg cgcggtcacg gcggactccc acaaagagac gccgtgcgat ccacgtcctg
    23701 aaacggacat ccgtggcaaa gatatgtcgg tgttccgcgc gctgattagt gagaataaac
    23761 tggatgcgat tatgcctgcc cacgtgatct accgcgctat cgatccgcgt ccggcaagcg
    23821 gttcgccgta ctggctgaaa acggtgctgc gtcaggagct aggctttgac ggcgtcattt
    23881 tctccgacga tctgtctatg gagggcgcgg cgattatggg cagctatgct gagcgcgctc
    23941 aggcgtcgct ggatgcgggt tgcgatatga ttctggtctg caataatcgt aaaggcgcag
    24001 tcagcgtgct ggataatctg tcgccgatca aagcagaacg tgttacacgt ttgtatcata
    24061 aaggttcatt ttcacgccgg gagctcatgg actcagcacg ctggaaaaca gccagcgccc
    24121 agctcaacca gttacatgaa cgctggcagg aagaaaaagc aggtcattaa ctcgagtttt
    24181 cgtgagggtg ccagatgatt atttatttac acggttttga ttcaaatagt ccgggtaacc
    24241 atgaaaaagt gttgcaatta caatttatcg acccggatgt tcggctggta agctacagta
    24301 cgcggcatcc taagcacgat atgcagcatc tgctgaaaga agtggacaaa atgttgcagt
    24361 tgaatgtgga cgagcgccct ttaatctgtg gcgtagggct gggcggttac tgggcggagc
    24421 ggattggctt tttgtgcgat atccgtcagg tggtttttaa cccgaacctg ttcccctatg
    24481 aaaacatgga ggggaaaatc gatcgcccgg aagaatatgc ggacatcgct acaaagtgcg
    24541 tgaccaactt tcgcgaaaaa aatcgcgatc gttgtctggt gatcctctcg cgtcatgacg
    24601 aagcgctgga cagccaacgc tcagcgcaag cgcttcaccc gttttatgaa attgtgtggg
    24661 atgaggaaca gactcacaaa ttcaaaaata tttcgccgca cttgcaacgt atcaaagcgt
    24721 ttaaaacgct ggggtaacgc catccggcaa tatggcgtta tcagtgaccg gataaccagc
    24781 cttgcggctg gtttttttat gctcaattct cgcaaactgt ctatcttttc agcatgaaaa
    24841 cttgatgcac atcaattttg gtatgaccaa tgcaccgttc atgctattct catatcagaa
    24901 gcttattctc atta
//
LOCUS       DAJVBX010000046        24904 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.046, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000046 DAJVBX010000000
VERSION     DAJVBX010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 24904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24904
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.046"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            330..713
                     /gene="panM"
                     /locus_tag="OPV72_001638"
     CDS             330..713
                     /gene="panM"
                     /locus_tag="OPV72_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase autocleavage activator
                     PanM"
                     /protein_id="HCR9913979.1"
                     /translation="MKLTILRLEHFSAQDQIDLGKIWPEYSASSLSVDETHRIYAARF
                     NERLLGAVRVTLSGTQGALDSLRVREITRRRGVGQYLVEEVIRDNPNVSSWWMADVGV
                     EDRSVMAAFMQALGFTAQHDGWEKR"
     gene            691..825
                     /locus_tag="OPV72_001639"
     CDS             691..825
                     /locus_tag="OPV72_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9913980.1"
                     /translation="MTAGRSAKRKPDGADAYPAYMPGEKIKTTSQFSKNFALQAGGKL
                     "
     gene            complement(909..2012)
                     /gene="livJ"
                     /locus_tag="OPV72_001640"
                     /pseudo
     CDS             complement(909..2012)
                     /gene="livJ"
                     /locus_tag="OPV72_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026223.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="branched chain amino acid ABC transporter
                     substrate-binding protein LivJ"
     gene            complement(2334..3188)
                     /gene="rpoH"
                     /locus_tag="OPV72_001641"
     CDS             complement(2334..3188)
                     /gene="rpoH"
                     /locus_tag="OPV72_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoH"
                     /protein_id="HCR9913981.1"
                     /translation="MTKEMQNLALAPVGNLESYIRAANAWPMLSADEERALAERLHYQ
                     GDLEAAKTLILSHLRFVVHIARNYAGYGLPQADLIQEGNIGLMKAVRRFNPEVGVRLV
                     SFAVHWIKAEIHEYVLRNWRIVKVATTKAQRKLFFNLRKTKQRLGWFNQDEVEMVARE
                     LGVSSKDVREMESRMAAQDMTFDMSSDDESDSQPMAPVLYLQDKSSNFADGIEDDNWE
                     EQAANRLTDAMQGLDERSQDIIRARWLDEDNKSTLQELADRYGVSAERVRQLEKNAMK
                     KLRAAIEA"
     gene            complement(3434..4489)
                     /gene="ftsX"
                     /locus_tag="OPV72_001642"
     CDS             complement(3434..4489)
                     /gene="ftsX"
                     /locus_tag="OPV72_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsX"
                     /protein_id="HCR9913982.1"
                     /translation="MNRRDAINQIRQFGGRLDRLRKSRGGTGGGRNAPGRQKPTPKPN
                     SRKTNVFNEQVRYAWHGALQDLKSKPLATFLTVMVIAISLTLPSVCYMVYKNVNQAAT
                     QYYPSPQITVYLQKTLDDDAAARVVGQLQAEQGVEKVNYLSREDALGEFRNWSGFGGA
                     LDMLEENPLPAVAVVIPKLDFQSTASLNTLRDRISQINGIDEVRMDDSWFARLAALTG
                     LVGRVSAMIGVLMVAAVFLVIGNSVRLSIFARRDTINVQKLIGATDGFILRPFLYGGA
                     LLGFSGAFLSLILSEILVMRLSSAVTEVAQVFGTKFDLNGLSFDECLLLLLVCSMIGW
                     IAAWLATVQHLRYFTPD"
     gene            complement(4482..5150)
                     /gene="ftsE"
                     /locus_tag="OPV72_001643"
     CDS             complement(4482..5150)
                     /gene="ftsE"
                     /locus_tag="OPV72_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HCR9913983.1"
                     /translation="MIRFEHVSKAYLGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTL
                     LKLICGIERPSAGKIFFSGHDITRLKNREVPFLRRQIGMIFQDHHLLMDRTVYDNVAI
                     PLIIAGASGDDIRRRVSAALDKVGLLDKARNFPIQLSGGEQQRVGIARAVVNKPAVLL
                     ADEPTGNLDDALSEGILRLFEEFNRVGVTVLMATHDIGLISRRSYRQLVLSDGHLHGG
                     LANE"
     gene            complement(5153..6628)
                     /gene="ftsY"
                     /locus_tag="OPV72_001644"
     CDS             complement(5153..6628)
                     /gene="ftsY"
                     /locus_tag="OPV72_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HCR9913984.1"
                     /translation="MAKQKKRGFFSWLGFGDKEQKQEQTEEQQIVEEQRPVEPPVETA
                     ADVDAQTPAHSKAETEAFAEEVVDVTEKVQESEKPQPVEPEPTAAIEMAAPQIAVERE
                     ELPLPEEVKDEAISPEEWQAEAETVEVIAAVEEEGENAAKFTDEELEAQALAAQAAEE
                     AVMVVPPAEEDAPVEAIVQEQEKPTKEGFFARLKRSLLKTKENLGSGFISLFRGKKID
                     DDLFEELEEQLLIADVGVETTRKIIANLTEGASRKQLKDAEALYGLLKDEMGEILAKV
                     DEPLNIEGKTPFVILMVGVNGVGKTTTIGKLARQFEQQGKSVMLAAGDTFRAAAVEQL
                     QVWGQRNNIPVIAQHTGADSASVIFDAIQAAKARNVDVLIADTAGRLQNKSHLMEELK
                     KIVRVMKKLDEEAPHEVMLTIDASTGQNAVSQAKLFHEAVGLTGITLTKLDGTAKGGV
                     IFSVADQFGIPIRYIGVGERIEDLRPFKADDFIEALFARED"
     gene            6754..7350
                     /gene="rsmD"
                     /locus_tag="OPV72_001645"
     CDS             6754..7350
                     /gene="rsmD"
                     /locus_tag="OPV72_001645"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase"
                     /protein_id="HCR9913985.1"
                     /translation="MKKPTHSGSGQIRIIGGQWRGRKLPVPDSPGLRPTTDRVRETLF
                     NWLAPVMVDAHCLDCFAGSGALGLEALSRYAAQATLLEMDRAVSQQLQKNLATLKANN
                     ARVVNTNTLAFLSQPGTPHHVVFVDPPFRKGLLEETLQLLETQGWLADDALIYVESEV
                     ENGLPPVPANWALYREKVAGQVAYRLYQRDAQGENDVD"
     gene            7340..7609
                     /locus_tag="OPV72_001646"
     CDS             7340..7609
                     /locus_tag="OPV72_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1145 family protein"
                     /protein_id="HCR9913986.1"
                     /translation="MLINLGRLLMLFVWAFLILNLVHPFPRPLNIFVNVALVFMALMH
                     GMQLALLKSTIPKAGPQMTTGEKIRIFLFSVFELLVWQKKFKNKK"
     gene            complement(7631..8002)
                     /locus_tag="OPV72_001647"
     CDS             complement(7631..8002)
                     /locus_tag="OPV72_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2500 domain-containing protein"
                     /protein_id="HCR9913987.1"
                     /translation="MSKPPLFFIIIIALIVVAASFRFVQQRREKAANEAAPLQQKQVV
                     VSNKREKPVNDRRSRQQEVSPAGTSMRYEASFKPLNGGLEKTFRLQAQQYHALTVGDQ
                     GTLSYKGTRFVGFVSRTPDNE"
     gene            8144..8770
                     /locus_tag="OPV72_001648"
     CDS             8144..8770
                     /locus_tag="OPV72_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysoplasmalogenase"
                     /protein_id="HCR9913988.1"
                     /translation="MLWSFIAVCLSAWLYVDASYRGPAWQRWVFKPVTLLLLLLLAWQ
                     APMFDAISYLVLAGLCASLVGDALTLLPRQRLLYAVGAFFLSHLLYTIYFASQMTLSF
                     FWPLPLALLIVGALLIAVIWTRLEELRWPVCTFIAMTLVMVWLAGELWFFRPTAPALS
                     AFTGATLLFIGNIVWLGSHYRRRFRADNAIAAACYFAGHFLIVRSLYL"
     gene            8851..11049
                     /gene="zntA"
                     /locus_tag="OPV72_001649"
     CDS             8851..11049
                     /gene="zntA"
                     /locus_tag="OPV72_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Zn(II)/Cd(II)/Pb(II) translocating P-type ATPase
                     ZntA"
                     /protein_id="HCR9913989.1"
                     /translation="MSTPDTDGKKVPPFTSFRLAPAIQKADSCCCEEHCASSAPVSTA
                     VAGTRYTWKISGMDCAACARKVENAVRQIRGVNQAQVLFATEKLVVDADTDLRAQIEH
                     AVQKAGYTLRSEDSRDAAPESRLKENLPLITLIIMMAISWGLEQFNHPFGQLAFIVTT
                     LVGLYPIARQALRLMKSGSWFAIETLMSVAAIGALFIGATAEAAMVLLLFLIGERLEG
                     WAASRARKGVSALMALKPETATRLRDGVREEVAINTLRPGDIIEVAAGGRLPADGKLV
                     SGFASFDESALTGESIPVERATGDKVPAGATSVDRLVTLEVLSEPGASAIDRILTLIE
                     EAEERRAPIERFIDRFSRIYTPVIMVIALLVTLIPPLMFDGGWQEWIYKGLTLLLIGC
                     PCALVISTPAAITSGLAAAARRGALIKGGAALEQLGRITQVAFDKTGTLTIGKPRVTA
                     IHPASGISEAELLALAAAVEQGATHPLAQAIVREAQTRDLAIPTAESQRTLAGTGIEA
                     QVNGERILICAAGKQPAAAFAGQISELENAGQTVVLVLRNETVVGVLALQDTLRDDAR
                     DAIRELHQLGVNGVILTGDNPRAAAAIAGELDLAFKTGLLPEDKVRAVTALNQQAPLA
                     MVGDGINDAPAMKAASIGIAMGSGTDVALETADAALTHNRLRGLAQMITLARATHANI
                     RQNITIALGLKAIFLVTTLLGFTGLWLAILADTGATVLVTANALRLLRKN"
     gene            11246..12889
                     /locus_tag="OPV72_001650"
     CDS             11246..12889
                     /locus_tag="OPV72_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis citrate transducer"
                     /protein_id="HCR9913990.1"
                     /translation="MKNIKVITGVIATLGIFSALLLVTGILFYSAVSSDRLNFQNASA
                     LSYQQQELGGSFQTLIETRVTINRVAIRMLKNQRDPASLDAMNTLLTNAGASLNEAEK
                     HFNNYVNSEAIAGKDPALDAQAEASFKQMYDVLQQSIHYLKADNYAAYGNLDAQKAQD
                     DMEQVYDQWLSQNAQLIKLASDQNQSSFTQMQWTLGIILLIVLIVLAFIWLGLQRVLL
                     RPLQRIMAHIQTIADGDLTHEIEAEGRSEMGQLAAGLKTMQQSLIRTVSAVRDNADSI
                     YTGAGEISAGSSDLSSRTEQQASALEETAASMEQLTATVRQNTDNARQATGLAKTASE
                     TARKGGRVVDNVVSTMNDIAESSEKIVDITSVIDGIAFQTNILALNAAVEAARAGEQG
                     RGFAVVAGEVRTLASRSAQAAKEIKVLIENSVSRIDTGSTQVREAGETMKEIVNAVTR
                     VTDIMGEIASASDEQSKGIEQVAQAVSEMDSVTQQNASLVEESAAAAAALEDQANELR
                     QAVAAFRIQKQPRREASPTPLSKGLTPQPAAEQANWESF"
     gene            complement(12913..13158)
                     /gene="tusA"
                     /locus_tag="OPV72_001651"
     CDS             complement(12913..13158)
                     /gene="tusA"
                     /locus_tag="OPV72_001651"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase TusA"
                     /protein_id="HCR9913991.1"
                     /translation="MSDLFSSPDHTLDALGLRCPEPVMMVRKTVRNMQTGETLLIIAD
                     DPATTRDIPGFCTFMEHDLLAQETEGLPYRYLLRKAH"
     gene            13328..13993
                     /locus_tag="OPV72_001652"
     CDS             13328..13993
                     /locus_tag="OPV72_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-cyano-7-deazaguanine/7-aminomethyl-7-
                     deazaguanine transporter"
                     /protein_id="HCR9913992.1"
                     /translation="MTPFTQSQRIKALFWLSLFHLLVIISSNYLVQLPITIFGFHTTW
                     GAFSFPFIFLATDLTVRIFGAPLARRIIFAVMIPALLVSYVVSSLFYMGAWQGFAALA
                     NFNLFVARIAAASFMAYALGQILDVHVFNRLRQNRRWWLAPTASTLFGNISDTLAFFF
                     IAFWRSPDAFMAGHWMEIALVDYCFKVLISIIFFLPMYGVLLNMLLKKLADKSEISPL
                     PAS"
     gene            14066..14623
                     /locus_tag="OPV72_001653"
     CDS             14066..14623
                     /locus_tag="OPV72_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DcrB family lipoprotein"
                     /protein_id="HCR9913993.1"
                     /translation="MRNLVKYAGIGLLVMGLAACDNNDTKASAESAAAESQASGQPIS
                     LMDGKLSFSLPADMTDQSGKLGTQANNMHVYSDPTGQKAVIVIVGDNTDEALPVLANR
                     LLEQQRSRDPQLQVVTNKSIELKGHTLQQLDSIISAKGQTAYSSIVLGKVDNQLLTIQ
                     VTLPADNQQKAQTTAENIINTLVIK"
     gene            complement(14627..15886)
                     /locus_tag="OPV72_001654"
     CDS             complement(14627..15886)
                     /locus_tag="OPV72_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462482.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR9913994.1"
                     /translation="MIEKKTCCKNAVILMPEPVAEPALNGLRLNLRIVSIVMFNFASY
                     LTIGLPLAVLPGYVHDAMGFSAFWAGLIISLQYFATLLSRPHAGRYADVLGPKKIVVF
                     GLCGCFLSGLGYLLADIASAWPMINLLLLGLGRVILGIGQSFAGTGSTLWGVGVVGSL
                     HIGRVISWNGIVTYGAMAMGAPLGVLCYAWGGLQGLALTVMGVALLAVLLALPRPSVK
                     ANKGKPLPFRAVLGRVWLYGMALALASAGFGVIATFITLFYDAKGWDGAAFALTLFSV
                     AFVGTRLLFPNGINRLGGLNVAMICFGVEIIGLLLVGTAAMPWMAKIGVLLTGMGFSL
                     VFPALGVVAVKAVPPQNQGAALATYTVFMDMSLGVTGPLAGLVMTWAGVPVIYLAAAG
                     LVAMALLLTWRLKKRPPSALPEAASSS"
     gene            15976..17025
                     /locus_tag="OPV72_001655"
     CDS             15976..17025
                     /locus_tag="OPV72_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCR9913995.1"
                     /translation="MATAQPDKTGMHILLKLASLVIILAGIHAAADIIVQLLLALFFA
                     IVLNPLVTWFIRRGVKRPLAITIVVVVMLIVLTALVGVLAASLNEFIAMLPKYSKELT
                     RKVLHLQELMPFLNLHMSPERMLRGMDSDKIMLFTTTLMTGVSGAMASIVLLVMTVVF
                     MLFEVRHVPYKLRFALNNPQIHIAGLHRALKGVSHYLALKTLLSLWTGAIIWLGLALM
                     DIQFALMWGVLAFLLNYVPNIGSVISAVPPMIQALLFNGFYECVLVGALFLVVHMVIG
                     NIMEPRMMGHRLGMSTLVVFLSLLVWGWLLGPVGMLLSVPLTSVCKIWMETTKGGSKL
                     AILLGPGRPKSRLPG"
     gene            17077..17655
                     /gene="acpT"
                     /locus_tag="OPV72_001656"
     CDS             17077..17655
                     /gene="acpT"
                     /locus_tag="OPV72_001656"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase AcpT"
                     /protein_id="HCR9913996.1"
                     /translation="MYQIVLGKVSTLSAGQLPDALIAQAPQGVRRASWLAGRVLLSRA
                     LSPLPEMVYGEQGKPAFSAGTPLWFNLSHSGDTIALLLSDEGEVGCDIEVIRPRDNWR
                     SLANAVFSLGEHAEMEAERPERQLAAFWRIWTRKEAIVKQRGGSAWQIVSVDSTLPSA
                     LSVSQCQLDTLSLAVCTPTPFTLTPQTITKAL"
     gene            17746..18147
                     /gene="nikR"
                     /locus_tag="OPV72_001657"
     CDS             17746..18147
                     /gene="nikR"
                     /locus_tag="OPV72_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-responsive transcriptional regulator
                     NikR"
                     /protein_id="HCR9913997.1"
                     /translation="MQRVTITLDDDLLETLDSLSQRRGYNNRSEAIRDILRGALAQEA
                     TQEHGTQGFAVLSYVYEHEKRDLASRIVSTQHHHHDLSVATLHVHINHDDCLEIAVLK
                     GDMGDVQHFADDVIAQRGVRHGHLQCLPKED"
     gene            complement(18252..19073)
                     /locus_tag="OPV72_001658"
                     /pseudo
     CDS             complement(18252..19073)
                     /locus_tag="OPV72_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462486.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            complement(19073..21814)
                     /gene="rbbA"
                     /locus_tag="OPV72_001659"
     CDS             complement(19073..21814)
                     /gene="rbbA"
                     /locus_tag="OPV72_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated ATPase/putative transporter
                     RbbA"
                     /protein_id="HCR9913998.1"
                     /translation="MTSLTLVPVPPVAQLEGVSQHYGKTVALNNITLDIPARSMVGLI
                     GPDGVGKSSLLSLISGARVIEQGNVIVLGGDMRDAKHRRDVCPRIAWMPQGLGKNLYH
                     TLSVYENVDFFARLFGHDKAEREARITELLNSTGLAPFRDRPAGKLSGGMKQKLGLCC
                     ALIHDPELLILDEPTTGVDSLSRAQFWDLIDSIRQRQTNMSVLVATAYMEEAERFDWL
                     VAMNAGEILATGSAQQLRAKTHSATLEQAFIALLPEAQRQAHKPVVIPPYHAEQEEIA
                     IEAKDLTMRFGKFVAVDHVNFRIPRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGQAW
                     LFGQPVDPNDIDTRRRVGYMSQAFSLYNELTVRQNLELHARLFHIPPAEIPARVAQMI
                     ERFMLTEVEDTLPASLPLGIRQRLSLAVAVIHRPEMLILDEPTSGVDPVARDMFWQLM
                     VDLSRQDKVTIFISTHFMNEAERCDRMSLMHAGKVLASGTPQELVQQRGAANLEAAFI
                     SWLQEAAGAAPETPIPPSQTPAASDKPSRQGLSFRRLFSYSRREALELRRDPVRSTLA
                     LLGTVILMLIMGYGISMDVENLRFAVLDRDQTVSSQAWSLNLAGSRYFIEQPPLASYD
                     ELDRRMRSGELAVAIEIPPNFGRDIARGTPAQIGVWVDGAMPSRAETVKGYVQAMHQS
                     WLQEAASRQPNPVKQTGLLNIETRYRYNPDVKSLPAIVPAVIPLLLMMIPSMLSALSV
                     VREKELGPMINLYVTPTTRSEFLLGKQLPYIALGMLNFLLLCALSVFVFGVPLKGSFL
                     TLTLAALLYVIIATGLGLLISTFMKSQIAAIFGTSIITLIPATQFSGMIDPVASLEGP
                     GRWIGEIYPTSHFLTIARGTFSKALDLSDLWSLFMPLLIAVPVVMGLSILLLKKQEG"
     gene            complement(21811..22878)
                     /locus_tag="OPV72_001660"
     CDS             complement(21811..22878)
                     /locus_tag="OPV72_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="HCR9913999.1"
                     /translation="MDKMKRHLVWWGAGILVAVAAIAWWMLRPAGIPEGFAASNGRIE
                     ATEVDIATKIAGRIDTILVSEGQFVRQGEVLAKMDTRVLQEQRLEAIAQIKEAESAVA
                     AARALLEQRQSEMRAAQSVVKQREAELDSVSKRHVRSRSLSQRGAVSVQQLDDDRAAA
                     ESARAALETAKAQVSAAKAAIEAARTSIIQAQTRVEAAQATERRIVADIDDSELKAPR
                     DGRVQYRVAEPGEVLSAGGRVLNMVDLSDVYMTFFLPTEQAGLLKIGGDARLVLDAAP
                     DLRIPATISFVASVAQFTPKTVETHDERLKLMFRVKARIPPELLRQHLEYVKTGLPGM
                     AWVRLDERVPWPDDLNVRLSQ"
     gene            23656..>24904
                     /locus_tag="OPV72_001661"
     CDS             23656..>24904
                     /locus_tag="OPV72_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR9914000.1"
                     /translation="MKTSNFQKWLMVILLAIGGGTIFKSMYLREVFYYPWNEFMGVNN
                     TDSGLLMSWLGFVGIVSSSIAGVIIDKVNNTRLIISFTFLAVGVTTLWQSTAPGLATQ
                     YVIIGILSFLANGLFLVSMVRATRLIGNASDQGKLFGFLESGRGIAGSAISAVAVAWF
                     AMSATEVEGIGSVLHAYGFLYLALGVLMWFAMPRDNHNSASGEEKAKEKISVHDILAV
                     MKVKEVWFAAFSIFATISFYQGSSYLVPYLSDVYGMTAEHAGIIGMIRAYVLAILIAP
                     VVGLLADKVGSAIKVMNWLFIAGVIGVAMFLVIPQDPAMVWVLIGTLMIVGSINFALR
                     GIMYAQIEEMKVPVRLTGTVMGIMATVGFSPEMFIHALFGYWLDAYKVQGYTYMFIFM
                     GAMFALAVFTSLLLLRNAKTAFKK"
BASE COUNT         5680 a         7059 c         6494 g         5671 t
ORIGIN      
        1 actcattaat gagttagcgc agcatttaaa gcataataag attaaaatct ctatttttca
       61 gtctattaag aaaatataat attctgcttt tcgttataga taaacaaaaa aaagcacgct
      121 tgtcagcata aaataacggc acattaagcg gaataattca ctagcattca gggaattatg
      181 ctgcctgttt tccattctct aatgcttcaa actgtaatta tcgttgttaa aaaattaata
      241 acctggtaaa tgacacaaaa aagagaaagc atctggcctg cctgtttcgg tacactgatc
      301 gcatcttttg aaatcgggac aagccgtcga tgaagctgac cattcttcgt ttagaacact
      361 ttagcgctca ggatcagatc gatctgggca aaatctggcc ggaatattcc gcctcctcat
      421 taagcgtaga tgaaacgcac cggatttatg ccgcgcggtt taacgagcgt ttgttgggcg
      481 ccgtaagagt gacgctgagc ggaacgcagg gcgcgctgga ttccttacgc gtgcgtgaaa
      541 tcacccgtcg ccgcggcgtc gggcaatacc tggtagaaga ggtcatccgc gataatccca
      601 acgtctcgtc gtggtggatg gcggatgtcg gtgttgaaga ccgcagcgtg atggccgcgt
      661 ttatgcaggc gttaggtttt accgcccagc atgacggctg ggagaagcgc taaaagaaag
      721 ccggatggcg ctgacgctta tccggcctac atgccgggag aaaagataaa aaccacctcg
      781 caattttcca agaatttcgc gttgcaggca ggcggcaagt tatgaaatcc ccggaagctt
      841 acataagtaa gtgaccgggg ttgaataacg tagccaacgc acctgcagcg cgaaaggcgc
      901 caggaaaatt acttagcgtc tgtcgccgta ccattcgcat gccagtcaaa cacgccgaac
      961 tcaaatcctt tcagatcgcc tttctcatcc cacgacagcg gtcccattac ggtgtcgacc
     1021 gtggtgcctt tcaggtattt ggcaatttcc gccggatcgt cagactggtt cagacccgcc
     1081 tgcaacgatt gcagcgcggc gtaggtggtc cacacgaatg cgccgctagg atcttgtttc
     1141 ttggctttga tggcatccac aatcggtttg ttcgccggga cctgatcgta gttcttcggt
     1201 ttggtgacca gtaagccttc cgccgactct ccggcgatgt tagacagcga gacgttcgcc
     1261 accccttccg gccccataaa ctgggttttc agccctgcgg cgcgggactg gcgcaaaatc
     1321 tgccccattt ccgggtgata accgccgtag tagacaaagt cgatattctc ttttttcaga
     1381 cgcgctacca gagtggagaa atctttttcg ccggcggtaa tgccgtcaaa gaatacgacg
     1441 ttaacgccgc ctttcttcag accgtcctgc accgcgcgcg ccagcccttc gccgtactgc
     1501 tgcttatcgt ggataatcgc gatgcgctgc ggttttacct tctccagaat atactttgcc
     1561 gccgttggtc cctagtcaga gtccaggccg gtcgtgcgca aaatcaggtt atagccgcgc
     1621 gcggtcagct ccggtgcggt cgccgccggg gttatcatca ggatgccttc gtcttcgtag
     1681 atatcagacg ctggctgtgt ggaagaggag cataagtgac cgataacata cttgatgccg
     1741 tcgttcacca ctttgttagc gaccgctacc gcctgttttg gatcacaggc gtcgtcatat
     1801 ttcaccgcga cgagcttatc gcctttaata ccgcctttcg cattgatatc ggcaattgcc
     1861 tgctccgcac cggtaaattc ctggtcgcca tactgcgcca ccggaccgga catcgcgccg
     1921 acaaccgcga ctttaatgtc ctctgcgaat gccatatggc ttaatgacag ggcgatacat
     1981 cctgccaata acgttttacc cttcatattc atcctgataa tccccattat tctggttgtt
     2041 acgtgtgttg tggtgttatt gttcagcact ttatttcgat tattggctag ctacccgtgc
     2101 tttagcagca tactctgcta aaacataccc gatttttatt attttggaat agctaaattt
     2161 acatccagat aacagatttg tgtcggtggg ggagaggaag ggcccgtagg ccagataagc
     2221 gaagcgacat cgggcaaacg tgttgccgga tagcagcgta aacgccttat ccggcctaca
     2281 aaaaacaaaa cccccgaatt cacattcgag ggttcattgg caattcgcga agattacgct
     2341 tcgatcgcag cgcgaagctt tttcatggcg ttcttttcaa gctggcgcac acgctcagcg
     2401 gagacgccgt aacgatcggc cagctcctgc aacgtagact tattgtcttc gtccagccag
     2461 cgagcgcgga taatatcctg gctacgctcg tcgagcccct gcatcgcatc ggtcagtcgg
     2521 ttagcggcct gctcttccca gttatcgtct tcaatgccgt cggcaaagtt agacgattta
     2581 tcctgcagat acagcaccgg cgccattggc tggctgtcgg actcatcgtc cgaagacatg
     2641 tcaaacgtca tgtcctgcgc cgccatacgc gactccatct cacgcacgtc tttactggaa
     2701 acacccagtt cgcgcgccac catttcaacc tcatcctgat taaaccagcc cagacgctgc
     2761 ttggttttac gcagattaaa gaacagctta cgctgcgctt tcgtggttgc gactttaacg
     2821 atacgccagt tacgcagcac gtattcgtga atttctgctt taatccagtg tacggcgaag
     2881 gagaccaggc gcacgcctac ttccgggttg aaacgacgta cggctttcat caggccgatg
     2941 ttgccttcct ggatcaaatc cgcctgcggc agaccatagc ccgcatagtt acgagcaata
     3001 tgaacaacaa agcgcaggtg agacaggatc agcgttttag ctgcttccag atcgccctgg
     3061 taatgcagcc tttcagccaa tgcccgctcc tcgtcagccg ataacatcgg ccacgcgttc
     3121 gccgcccgga tataagattc caggttgcca acaggggcta aagctaaatt ttgcatttct
     3181 ttggtcattc aaatcctctc aatcagtatt gcctggcacc gtcagcgagc aacaaccgtg
     3241 ccaaagccga tgagcaacga gaatatcatc cactctttta tcagacagtg attttatcca
     3301 caagttcaat gtaacactgt gcataattta cacacataat gtgacatgaa gatgaaacgc
     3361 ggggaagaga caacagggac tctttccctg cgaacggaag cccattgcag ggaaagatta
     3421 taccacgatt ttatcaatcg ggagtaaagt aacgtaaatg ttgcaccgta gccagccaag
     3481 cggcgatcca gccgatcatg gaacagacca gcagcagcaa caggcactca tcgaacgata
     3541 aaccattgag atcaaacttc gtgccgaaga cctgcgccac ttcagtcacc gccgatgata
     3601 aacgcatcac caaaatttca gacaatatca gtgaaagaaa cgcgccggaa aaaccgagca
     3661 atgcgccgcc gtagaggaac ggacgcagga taaagccatc ggtcgcgcca atcagctttt
     3721 gcacgttaat ggtgtcgcga cgggcaaaaa tgctcaggcg cacgctgttg ccgataacga
     3781 ggaagaccgc cgcgaccatc agcacgccaa tcatcgccga cacgcggccc accagcccgg
     3841 tgagcgccgc cagacgcgca aaccagctat catccatgcg gacttcgtca atgccgttaa
     3901 tctgcgagat acggtcgcgc agcgtattaa gcgaggcggt actttgaaag tccagcttgg
     3961 ggatcaccac cgccaccgcc ggtagcgggt tctcttccag catgtccagc gcgccgccaa
     4021 aacccgacca gttgcggaat tcgcccagcg cgtcctcacg ggacaggtag ttgaccttct
     4081 caacgccctg ctcggcctga agctgcccaa cgacccgcgc cgccgcgtca tcatccagcg
     4141 ttttttgcag ataaacggtg atctgcggcg acggatagta ctgagtcgcc gcctggttga
     4201 cgttcttata gaccatgtaa cagacgctgg gcagcgtcag ggagatggcg atcaccatca
     4261 ccgtcagaaa cgtcgccagc ggtttgcttt tcagatcttg cagcgcaccg tgccaagcat
     4321 agcgcacctg ttcattaaaa acatttgttt tacgtgagtt cggtttcggc gtcggcttct
     4381 ggcgtcctgg cgcgttgcgc ccgccgcctg ttccgccgcg agacttacgc agtcgatcca
     4441 gccgtccgcc gaactgcctg atttggttaa tcgcgtcgcg cctattcatt ggccaggcct
     4501 ccatgcagat gtccatcgct caggacgagc tgcctatagg aacgacgcga gataagtcca
     4561 atatcgtgcg tcgccatcag taccgtcacc cctacgcggt taaactcttc aaacagacgt
     4621 aaaatccctt ccgacaacgc gtcgtccagg ttcccggtcg gttcatccgc cagcaatacc
     4681 gctggcttat tgaccaccgc gcgggcgatg cccacgcgct gttgttcgcc tccggagagt
     4741 tgaatcggga agtttctcgc tttgtccagt agtccaacct tatccagcgc cgccgacaca
     4801 cgacgacgga tatcatcgcc gctggcgccg gcaatgatta acggtatcgc cacattgtca
     4861 tagaccgtgc gatccatcag cagatggtga tcctggaaaa tcatcccaat ctggcggcgc
     4921 aaaaacggca cttcgcggtt tttcaggcgc gtaatatcat gcccgctgaa gaagattttg
     4981 ccggcgctgg gccgctcaat cccacagatt agcttcagca gggtactttt ccccgcgccg
     5041 gagtggccgg tcagaaacgc catctcgcct ggccgcatat ggaatgtcac tccctgcagc
     5101 gcttgtctcc cgccgagata ggccttgctg acatgttcaa agcgaatcat tgttaatcct
     5161 ctcgggcaaa aagtgcctca ataaaatcgt ccgccttaaa cggacgcaaa tcctcgatac
     5221 gttcgcccac gccaatgtaa cggataggaa tgccaaactg gtcagctacc gagaaaatca
     5281 ccccgccttt cgccgtaccg tccagcttgg tcagggtaat accggttaag cccaccgctt
     5341 catggaacag tttggcctgg cttaccgcgt tctgtccggt gctggcgtca atggtcagca
     5401 taacttcatg tggcgcttct tcgtccagct ttttcatgac gcgaacgatt tttttcagct
     5461 cttccatcag gtgcgacttg ttctgcaaac gccctgccgt atcggcaatt aacacatcca
     5521 cattacgcgc cttcgcggcc tggatagcgt caaaaatcac cgaggcggag tccgcgccgg
     5581 tatgctgggc gataaccgga atgttgttac gctgtcccca gacctgtagc tgttcgaccg
     5641 ccgccgcgcg gaaagtatcc cccgccgcca gcatcactga tttaccctgc tgctcaaact
     5701 ggcgcgccag tttaccgata gtggtggttt tacccacgcc gttcacgcca accatcagaa
     5761 taacaaaagg cgttttacct tcaatattaa gcggttcgtc taccttcgcc agaatctcgc
     5821 ccatctcgtc tttcaacaga ccatacagcg cctcggcatc tttaagctgt ttgcggctgg
     5881 cgccttccgt cagattagcg ataatcttac gcgtggtttc caccccgaca tcagcgatga
     5941 gcaactgctc ttccagctcc tcgaacaaat catcgtcgat tttcttgccg cggaacagac
     6001 tgataaatcc ggaaccgaga ttttctttgg ttttcagcag actgcgtttc aggcgggcaa
     6061 agaaaccttc tttagtcggt ttttcctgct cctgaacgat cgcttccacc ggcgcgtctt
     6121 cttccgccgg cggaacaacc atcaccgcct cttccgccgc ctgagcggcc agcgcctgcg
     6181 cttccagctc ttcgtcggtg aatttcgccg cgttttcgcc ctcttcttct accgcggcaa
     6241 tgacctctac ggtttccgct tcggcctgcc actcttccgg cgagatagcc tcgtctttga
     6301 cctcttccgg cagcggcaat tcctcgcgtt ccaccgcgat ctgcggcgct gccatctcaa
     6361 tggccgccgt gggctccggc tctaccggct gcggtttttc gctctcctga actttctcag
     6421 taacgtccac cacctcttcc gcaaaggctt ctgtttctgc tttgctgtgc gcgggcgttt
     6481 gcgcgtctac gtctgccgcc gtttcaacag ggggctcaac cggtcgttgt tcctcaacaa
     6541 tctgctgttc ttcggtctgt tcctgcttct gctctttatc accgaagccc aaccaggaaa
     6601 agaagccacg ttttttctgt tttgccatct gcgactacac ccctcgcggc gctatataca
     6661 tggaagctaa aaaaatgatg aaatagtcta tcacttaact taattcacat caccgcctgg
     6721 aataacttgc aacaggcggt tcgagcaaga gaaatgaaaa aaccgactca ctctggcagc
     6781 ggccaaatcc gcattattgg cgggcaatgg cgtggccgta aattaccggt tccggacagc
     6841 ccgggtctgc gtcctaccac cgatcgcgtg cgcgaaacgt tatttaactg gctggctccg
     6901 gtaatggtag acgcccattg tctggattgc tttgccggca gcggcgcgct gggtctggaa
     6961 gcgctatcgc gttatgcggc ccaggcaacg ttactggaaa tggatcgcgc cgtatcgcag
     7021 cagttgcaaa aaaatctggc gacgctgaaa gccaacaatg ctcgcgtcgt caataccaat
     7081 actctggcct tcctcagcca gccggggacg ccgcatcacg tcgtctttgt cgacccgccg
     7141 tttcgtaaag gactgctgga agagacgtta caattgctag aaacccaggg atggctggcc
     7201 gacgacgcgc taatctacgt agaaagcgag gtggaaaacg gtctgccgcc cgttccggcg
     7261 aactgggcat tgtatcgaga aaaggtggcc ggacaggtcg cttatcgtct gtatcagcgc
     7321 gacgcgcaag gagaaaatga tgttgattaa tctgggccgc ttattaatgc tcttcgtgtg
     7381 ggcatttttg attcttaatc tggtgcatcc cttcccgcgc ccgctcaata tcttcgtcaa
     7441 cgtggcgttg gtgttcatgg cgctgatgca cggtatgcag ttggcgttgc tgaaatcaac
     7501 gataccgaaa gcgggtccgc agatgacgac gggagagaaa atccgcattt tcctgttcag
     7561 cgtgtttgag ctgctggtct ggcagaagaa gtttaagaac aaaaaataac gtttgctgcc
     7621 ggatgacggt ttattcgtta tccggggtac ggctaacaaa tccgacgaac cgcgttccct
     7681 tatagcttag cgtaccttga tcgcccaccg tcaaagcgtg gtactgctgc gcttgtaaac
     7741 ggaacgtttt ttccagaccg ccattgagcg gcttaaaact ggcctcatag cgcatactgg
     7801 ttcccgccgg gctcacttcc tgctggcgag agcgtcggtc gttaaccggc ttctcccgtt
     7861 tattgctgac cacgacctgc ttttgctgta acggcgccgc ctcattagcg gctttttccc
     7921 gccgttgctg aacgaagcgg aacgacgcgg caactacgat taatgcaatg attataatga
     7981 agaaaagcgg tggcttactc atactgttaa cctgtcagaa aatgcggaaa taagcatacc
     8041 ctgcccgtta tagtgttgtc atctgaccgt cacggcctct acactgaata atagagccgc
     8101 aagcataccg tttgcgaaaa aataacgaat tcaaggaatt aagatgcttt ggtcgtttat
     8161 cgctgtctgc ctgtccgcat ggctgtatgt ggacgcctcc tatcgcgggc cagcctggca
     8221 acgctgggtt tttaagcccg tcacgttatt actgttgctg ttactggcct ggcaagcgcc
     8281 gatgtttgac gccatcagtt atcttgtgtt ggccggactg tgcgcctcgc tggtcggcga
     8341 tgcgttaacg ctcttaccgc gtcaacgcct gctgtacgcc gtcggggcat ttttcttatc
     8401 gcatctgctc tacaccattt actttgccag ccaaatgacg ttgtcgttct tctggccgct
     8461 gccgctggcg ttactgatag tcggcgcgtt gcttatcgcc gttatctgga cgcgactgga
     8521 ggagctacgc tggccggtat gtacttttat cgccatgacg ctggtcatgg tctggctggc
     8581 gggcgaactg tggttcttcc gcccaacggc gccagccctt tcggccttta ccggcgcgac
     8641 gctgctgttc atcggcaata tcgtctggct gggtagccat taccgccgcc gtttccgggc
     8701 ggataacgcg attgccgccg cctgctactt tgcaggacac ttcctgattg ttcgctcgct
     8761 gtacctgtaa ataatagcgc ttgactctgg agtcgactcc agagtgtatc ctccggttaa
     8821 tgagaaaatt atcatcaacc ggaggacgtt atgtcgaccc ctgataccga tggcaaaaaa
     8881 gtcccgccct ttacctcctt cagattagcc ccggcaatac agaaggccga tagctgctgc
     8941 tgcgaagaac attgcgcgtc cagcgcgcct gtttctactg ccgtggcagg cacgcgctat
     9001 acctggaaaa tctccggcat ggactgcgcc gcctgcgccc gaaaagtgga gaatgcggta
     9061 cgccaaattc gcggcgtcaa ccaggcgcaa gtgctgttcg ccaccgaaaa gttagtggtc
     9121 gatgccgaca ccgacctccg cgcgcaaatt gaacacgccg tacagaaggc gggttatacc
     9181 ttgcgtagtg aagattcgcg cgacgccgcg cctgaatctc gtcttaaaga gaacctgccg
     9241 cttattacgc tgatcattat gatggcgata agctgggggc tggagcaatt taaccacccg
     9301 ttcggccaac tggcctttat cgtcaccact ctggtcggtc tgtatcctat tgcccgccag
     9361 gcgctgcggc tgatgaaaag cggcagttgg ttcgctattg aaacgctgat gagcgtcgcc
     9421 gccattggcg cgctgtttat aggcgcgacg gcggaggcag caatggtatt gctgctgttc
     9481 ctcatcggcg agcgcctgga aggatgggcc gccagccgcg cccgtaaagg cgtcagcgcg
     9541 ttaatggcgc ttaaaccgga aacggcgacc cgtctgcgcg acggcgtgcg ggaagaggtc
     9601 gctattaata ccctgcgacc gggcgatatt atcgaagtcg ccgccggggg gcgtttaccc
     9661 gccgacggta aactggtttc cggtttcgcc agctttgatg aaagcgcgct caccggcgag
     9721 tctatccctg tggagcgcgc aacgggcgac aaagtcccgg caggcgcgac cagcgttgac
     9781 cgtctcgtca ccctggaggt gctatctgaa cctggcgcca gcgcgattga ccgtatcctg
     9841 acgctgattg aagaggcgga agagcgccgt gcgcccattg agcggtttat tgaccgtttc
     9901 agccgcatct atacgccagt cattatggtc atcgcgctgc tggtgacgct tattccgccg
     9961 ctgatgttcg atggcggctg gcaggagtgg atttataaag ggctgacgct gctattaatc
    10021 ggttgcccgt gcgcgctggt gatctccacg cccgcggcca ttacctccgg gctggcggcg
    10081 gcggcacggc gcggcgcatt gattaaaggc ggagcagcgc tggagcaact gggccgtatc
    10141 acgcaggttg cctttgataa aaccggtacg ttgaccatcg gtaaaccacg ggtgacggcg
    10201 attcatccgg caagcggtat cagcgaggct gaactgttgg cgctggcggc agccgtagaa
    10261 caaggcgcta cgcacccgct ggcgcaggct attgtccgcg aagcgcagac acgcgatctg
    10321 gcgatcccga cggcggaatc gcagcgaacg ctggccggca ccgggattga agcgcaggtt
    10381 aacggcgaac gtattctgat ttgcgcggcg ggaaaacagc ctgcggcagc gtttgccggg
    10441 caaattagcg aactggaaaa cgccgggcag acggtggttc tggtgctacg taacgagacc
    10501 gttgttggcg tcctcgccct ccaggatacg ttgcgtgacg atgcgcgcga cgccatccgc
    10561 gaactgcatc agttaggcgt taacggcgtg attctgaccg gcgataaccc acgggcggcg
    10621 gcagcgattg ccggcgagct ggatctggcg tttaaaaccg gactactgcc ggaagataag
    10681 gtgcgggcag tcaccgccct taaccaacaa gcgccgctgg cgatggtggg cgacggcatt
    10741 aatgatgcgc ccgcgatgaa agccgccagt atcggaattg cgatgggcag cggtactgac
    10801 gtcgcgctgg aaacggctga cgccgccctt actcataacc gtctgcgcgg gttagcgcag
    10861 atgattacgc tggcgcgcgc tacccacgcg aatatccggc agaacatcac cattgcgctg
    10921 gggctgaaag ccattttcct ggtgacgacg ctactgggtt ttaccgggct atggctggca
    10981 atcctggcgg atacgggagc cacggtatta gtgaccgcca acgcgctacg tttgctgcgt
    11041 aaaaactaat cttctcccac ccggcggcat gtcgccgggt tatcccgcga tattcctttc
    11101 tttgtacata ttattcacgc gaaaatcatt tattttctat tacttatcaa accattaatc
    11161 agaaatagcg cgatttgatg taaggttaat ttttatccaa ccgatattga tcataccgtc
    11221 tacaaaataa ggaatgttag gcactatgaa aaatatcaaa gtcatcaccg gcgttatcgc
    11281 gacgctgggc atatttagcg ccttattgtt ggtgacagga atactgtttt attccgccgt
    11341 cagcagcgat cggctgaatt tccagaatgc gagcgcactg agttaccaac aacaggaact
    11401 gggcggcagt tttcagacat tgattgaaac ccgcgtcacc attaaccgcg tggcgatacg
    11461 catgttaaaa aatcagcgcg atcccgcctc gctggacgcc atgaacacgc tgttaaccaa
    11521 cgctggcgcg tcgctcaacg aagcggaaaa gcatttcaac aactacgtga actccgaagc
    11581 gatcgcaggc aaagatccgg cgttggatgc ccaggccgaa gccagcttta agcagatgta
    11641 tgacgttttg cagcagtcta tccactatct taaagccgat aattacgccg cctatggcaa
    11701 ccttgacgcg caaaaagcgc aggatgacat ggagcaggta tatgaccagt ggctctctca
    11761 aaatgcgcaa ttaataaaat tagccagcga tcagaatcag agcagtttta cccagatgca
    11821 atggacgctg gggataattc tacttatcgt gctcatcgtg ctggcgttta tctggctggg
    11881 gctgcaacgc gttctactcc gcccgctgca acggattatg gcgcacattc aaacgatcgc
    11941 cgacggcgat cttacccatg agatagaggc tgaaggacgt agtgaaatgg gccaactggc
    12001 tgccggtctc aaaacgatgc agcagtcgtt aatccgtacc gtcagcgcgg tgcgcgataa
    12061 cgcagactct atctatactg gcgcaggcga aatttccgct ggcagcagcg acctctcttc
    12121 ccgtaccgaa cagcaggcct cggcgctgga ggagaccgcc gccagcatgg aacagttaac
    12181 cgccacggta cggcaaaaca ccgataacgc acgacaggcg acgggtctgg cgaaaaccgc
    12241 atcagaaacc gcgcgtaaag gaggacgcgt ggtggataac gtagtgagca ccatgaacga
    12301 tatcgccgaa agctcggaaa aaatcgtgga catcaccagc gtgattgacg gtatcgcctt
    12361 ccagactaat atcctggcgc tgaacgctgc ggtagaagcc gcccgcgccg gcgaacaggg
    12421 gcgaggattc gcggttgtgg ccggagaggt acgcacgttg gccagccgta gcgcgcaggc
    12481 cgccaaagag atcaaagtgc tgattgaaaa ctccgtgtcg cgcattgata ccggctctac
    12541 gcaggtacgc gaagcgggag aaaccatgaa agagatcgtt aacgccgtga cccgcgtgac
    12601 cgatattatg ggcgaaatcg cctctgcctc cgatgagcaa agcaaaggca ttgagcaggt
    12661 ggcgcaggcg gtatcggaaa tggacagcgt gacgcagcaa aacgcctcgc tggtagagga
    12721 atccgcagca gcagcggcgg cgctggaaga tcaggctaac gagcttcgtc aggcggtcgc
    12781 cgcgttccgc atccagaaac aacctcgtcg ggaggcgtcg ccgacgccgt taagcaaagg
    12841 cttaacgcca cagcccgccg cagaacaggc gaactgggaa agcttctaat cagaatgcta
    12901 tctgccgtgc ggttaatgcg ctttacgcaa taaatagcgg tacggcagac cctccgtctc
    12961 ttgcgccagc aaatcgtgtt ccataaaggt acagaacccc ggaatatcac gcgtcgtcgc
    13021 cggatcgtcg gcgataatca gcaatgtttc gccagtttgc atgttgcgca ccgttttgcg
    13081 caccatcatt accggttcag ggcaacgcag ccccagggcg tcaagcgtat ggtcagggga
    13141 ggaaaacaga tcgctcatct tcgtctcaat ggtagaaaaa cggcgatatt ttacgcccat
    13201 cttcgtcagt aagccaagca ggttaacgat tgcgtgaaaa ttagccattg caatgccagc
    13261 gcaaaacagt attatgcggc ggttctttat tgggttccct caccccatcc aacaaaaagg
    13321 tcacaatatg actccgttta cacaatcaca gcgcataaaa gcgttgttct ggctatcgct
    13381 attccattta ctggtgatca tttccagtaa ctatctggtg cagctcccca tcactatttt
    13441 tggtttccac acgacctggg gcgcgtttag ttttcctttt atttttctcg ccaccgatct
    13501 taccgtgcgt atttttggcg caccgctggc gcgccgcatt atcttcgccg tcatgatccc
    13561 tgcgctgctg gtgtcatatg tggtgtcatc gctgttctat atgggtgcct ggcaaggttt
    13621 cgccgcgttg gcgaacttta atctgttcgt cgcccgtatc gccgccgcca gctttatggc
    13681 ctacgcgctg ggacagatcc ttgatgtcca tgtgtttaac cgcctgcgcc aaaatcgtcg
    13741 ctggtggctg gcgccgaccg cttcaacgct gtttggcaat atcagcgata cccttgcctt
    13801 tttcttcatt gcgttctggc gaagccccga tgcctttatg gccgggcact ggatggaaat
    13861 tgcgctggtg gattattgct ttaaggtgct catcagcatt attttcttcc tgccgatgta
    13921 cggcgttcta ctgaatatgt tgctgaaaaa gctggcagat aaatctgaaa tttccccatt
    13981 accggcaagt taaaggttcg ttttccgagt tgtgataaga tgagcgaatg agccgttatg
    14041 gccgtttatc gaaaggaaga agtcaatgcg caatttggtt aaatatgccg gtattggcct
    14101 gctggttatg gggcttgcgg cctgtgataa caacgataca aaagcgtcgg cagaaagcgc
    14161 cgccgcagaa agccaggcct ccggtcagcc catcagcctg atggatggca aactcagttt
    14221 ctcactgccg gcggatatga ccgatcaaag cggtaagctg ggcacccagg cgaataatat
    14281 gcacgtttat tctgacccga cgggccagaa agcggtgatt gttatcgtcg gcgataatac
    14341 cgatgaagcg ttgccggtgc tggcgaaccg cctgcttgag caacagcgta gccgcgaccc
    14401 gcagcttcag gtcgtcacca ataagtctat tgagctcaaa ggccatacgt tgcaacagct
    14461 ggacagcatt atctccgcga aaggccagac ggcgtactct tccatcgtgc tgggcaaagt
    14521 ggataaccaa ttgctgacga ttcaggtcac gctgcctgcg gacaatcagc aaaaagcgca
    14581 aaccacagct gaaaacatca tcaatacgtt ggttattaag taaccttcac gacgatgatg
    14641 cggcctccgg cagtgcagac ggaggccgtt tttttaagcg ccaggtcagt aatagcgcca
    14701 tcgctaccag cccggccgcc gccagataaa tcaccggcac gcccgcccag gtcatcacca
    14761 gccccgccag cggcccggtc acccccaaag acatatccat aaagacggta taggtcgcca
    14821 gcgccgcgcc ctggttctgc ggcggcacgg ctttgacggc caccacaccc agcgccggaa
    14881 agaccagcga aaaccccatc cccgtgagta aaacgccgat ttttgccatc cacggcatgg
    14941 ctgccgtccc caccagtaac agaccaataa tctccacgcc aaagcagatc atggcgacat
    15001 tcaacccgcc taagcgattg ataccgttag ggaacagcaa acgcgtgccg acaaacgcga
    15061 cgctaaataa cgtgagcgca aaggcggcgc catcccaacc tttagcatca taaaataagg
    15121 taataaacgt cgcgatgacg ccaaaccctg ccgaggccag cgccaacgcc ataccataca
    15181 gccagacacg ccccagcacc gcgcgaaacg gcagcggctt gcctttgttc gccttcaccg
    15241 acggacgtgg aagggctaac agtaccgcca acagcgccac gcccatcacc gttagcgcca
    15301 gtccctgtaa cccgccccag gcataacaca gcacgcccag cggcgcgccc atcgccattg
    15361 cgccgtaggt gacgataccg ttccaggaga taacccgacc aatatgcaac gacccgacga
    15421 cgccgacgcc ccacagtgtc gaaccggtgc cggcaaaact ttgcccaatc cccaaaatca
    15481 cgcgacccag ccccagtagc aacaaattga tcatcggcca ggcgctggcg atatccgcca
    15541 gcaggtagcc gagtccgctt aaaaaacagc cgcataagcc aaagacaacg atttttttcg
    15601 gccctaatac atccgcatac cgcccggcat ggggacggct taacagagtg gcgaagtatt
    15661 gcaggctgat aataagcccc gcccagaacg cgctgaatcc catcgcatca tgcacatagc
    15721 cgggcaagac ggcgagcggc aggccgatag tcaggtagct ggcaaagtta aacatcacga
    15781 tggagacaat acgcagattg aggcgcaatc cgtttagcgc cggttcagcg acgggttcgg
    15841 gcatgagtat caccgcattt ttacaacatg ttttcttttc tatcatggcg cgcggtgaaa
    15901 atcagtagtg agattcagat tatcggtatc agggcagccg ctacacttag aaaaaaacac
    15961 aacaaggaaa acttcatggc aaccgctcaa cccgacaaaa cgggtatgca tattctgctg
    16021 aaactggcct ccctggttat tattctcgcc gggattcatg ccgcggcgga tattattgta
    16081 caactcttac tggcgctctt tttcgccatc gttcttaatc cattagtgac ctggtttatt
    16141 cgccggggcg tgaagcgacc gctggcgatt actatcgtgg tggtcgtcat gctgatcgtg
    16201 cttaccgcgc tggtgggtgt gcttgccgca tcgcttaatg aatttatcgc tatgctgcct
    16261 aaatacagca aggagctgac gcgtaaggtt ttacatcttc aggagttaat gcccttcctg
    16321 aatttacata tgtcgccgga acgtatgctc cgtgggatgg attccgataa aatcatgctc
    16381 ttcaccacaa cattaatgac cggcgtatcg ggcgcgatgg caagcattgt gctgctggtg
    16441 atgaccgtgg tttttatgct gtttgaggtg cgtcacgtgc cttataaatt acgtttcgcg
    16501 cttaacaatc cacaaatcca tattgccggc ctgcaccgcg ccctgaaagg cgtctcgcat
    16561 tatctggcgc tgaaaacgct gctcagtcta tggacgggcg cgattatctg gctggggctg
    16621 gcattaatgg atattcagtt tgcgctaatg tggggcgtac tggccttttt gctcaattac
    16681 gttcctaata tcggctcggt gatttccgcc gttcccccca tgattcaggc gttgttattt
    16741 aacggctttt acgaatgcgt actggtcggc gcgctctttt tggtggttca tatggtgatt
    16801 ggcaacatta tggagccacg catgatgggc catcgtctgg ggatgtccac gctggtggta
    16861 tttctttcgt tactggtctg gggatggcta ttaggcccgg tcgggatgct cttgtccgtt
    16921 cctttgacca gcgtctgcaa aatctggatg gaaaccacta aaggcggcag caaactggcg
    16981 atcttactgg ggccaggccg accgaaaagc cgtttaccgg gatgaggcga cagatgctac
    17041 aatctcctct tcttcatagg caacgttggt cctgatatgt accagatcgt tctgggaaaa
    17101 gtgtcaacat taagcgcagg tcaattgccc gacgcgttaa tcgctcaggc gccgcagggc
    17161 gttcgccggg caagctggct ggccgggcgc gtgctgcttt cccgtgcgct ctcgccgcta
    17221 ccggagatgg tgtatggcga acagggtaaa ccggcttttt ccgccggaac gccgctgtgg
    17281 tttaacctca gccatagcgg cgacactatt gctctgttgc ttagcgacga aggtgaagtc
    17341 ggctgcgata ttgaagtgat ccgcccgcgc gataactggc gttcgctggc aaatgcggta
    17401 ttcagcctcg gcgaacatgc tgaaatggaa gcggaacgtc cggagcgaca actggcggcc
    17461 ttctggcgta tctggacgcg taaagaagcc atcgtaaaac aacgcggcgg cagcgcctgg
    17521 caaatcgtca gcgtggacag cacgttgccc tctgccttgt cggtcagcca gtgtcagctc
    17581 gatacgctca gtctggcagt ctgtaccccc acaccgttta cgctgacgcc gcagacgata
    17641 acaaaagcgt tatgacacat taattttccc tctggcggcg gacgtgtgtt acaaaatgcg
    17701 gagcttccca tgcgccgacg cgccatacca aaaggtttaa gtcagatgca acgtgtcacc
    17761 atcaccctcg atgacgattt actggaaacg ctggacagcc tgagccagcg acgcggctat
    17821 aacaatcgct ccgaagcgat ccgtgatatt ctgcgcggcg ctctggcgca ggaggccacc
    17881 caggaacacg gtacacaggg tttcgcggta ctttcatatg tttatgaaca tgagaaacgg
    17941 gatttagcca gccgcatcgt ctccacccag catcatcatc atgatttatc cgtcgccacg
    18001 ctgcacgtcc atatcaacca cgatgactgt ctggagatcg ccgttctgaa gggcgatatg
    18061 ggcgacgtac agcattttgc cgatgatgtt atcgcccagc gcggcgtgcg ccacggccac
    18121 ttgcaatgtt tgccgaaaga agactaacgc cccagcgcct tgccgggggc gcttcgcttg
    18181 cccggcctac gttcgcacgt cgtcgtttgt aggccggatg aggcgcagcc gccatccggc
    18241 aataatgttt gcgccatcgt gccaatcgtt tttctgaagc gtaacagcgc tatcaggaag
    18301 aacacgccgc ctatcgccag cagggtcagg aactgcggcc agacaatact taaacctgcg
    18361 ccgcgataaa gaatagcctg ggcaaggctg acaaaatgcg tcgttggcat ggtcagcata
    18421 atatcctgca ccgcctgcgg catactttcg cgcggcgtgg aaccgccgga gagcatttgt
    18481 agcggcaaca gcaccagaat cattaataac cccagctgcg gcatcgaacg ggcgatggtg
    18541 cccataaaaa tcccaattga agtggtggcg aacaggctca gcgccacgcc caacataaac
    18601 aatgggatcg atccttcaat cggtacgcca agtacgcctt tcaccatcag catcaaagac
    18661 aaaccggaaa ccaccagcac gaccagcccc atcgaccaca cttttgccat catgatctca
    18721 aagggcgtga ccggcatcac taacagatgc tctaccgtgc catgttctcg ctcgcggatc
    18781 agcgccgatc cggtcagcac tatcgccagc atggtaatgt tgttgataat cgccatcacg
    18841 ccgccaaacc acgccgggtc cagattcggg ttaaagcgca tccgaatttc cagcgacacc
    18901 ggctgaacgc tatctccccg cgcgcgccac aaagctgttg acctcgccgc taataatatt
    18961 ctggatataa caatcgtaaa ggcgaagacg atcagcgcca gcatcgcttt gtcgcccagc
    19021 agactgcgca gttctttgac gccgaggtta taaatattac gtaatccgcg cattacccct
    19081 cctgtttttt cagcagcaga atgctcagac ccatcaccac cgggacggca atcagtaacg
    19141 gcataaataa cgaccagaga tcggacagat ccaacgcttt ggaaaacgtc ccgcgcgcga
    19201 tcgtcagaaa atggctggtc gggtagatct cgccgatcca tcttcccggt ccttccagcg
    19261 aagccaccgg atcgatcatg ccggaaaatt gtgttgccgg aatgagggta ataatcgacg
    19321 tcccaaaaat agcggcgatt tggctcttca taaacgtgga gatcagcagc cccagaccgg
    19381 tggcgatgat gacgtaaagc agcgccgcga gggtaagcgt gagaaagctg cctttcagcg
    19441 gcacgccgaa cacaaagacc gacagcgcgc acagtagcaa gaagttcagc atacccagcg
    19501 cgatatacgg cagttgttta cccagcaaaa attcactgcg cgtcgtcggc gttacgtaca
    19561 gattaatcat cggccccagc tctttctccc gcaccacgct cagggcgcta agcattgacg
    19621 ggatcatcat gagcagcagc ggaatgaccg ccggaacgat agcgggcaga cttttcacat
    19681 ccgggttata gcgatagcgc gtttcaatgt tgagcagccc ggtttgttta accgggttcg
    19741 gctgacgact tgccgcctcc tgcagccagc tttggtgcat cgcctgaacg taccccttca
    19801 ccgtctcggc gcggctgggc atggcgccat ccacccagac gccaatctgc gctggcgtac
    19861 cgcgagcaat atcgcggcca aaattaggcg ggatctcaat ggcaaccgcc aactctcccg
    19921 aacgcatccg ccggtcaagc tcgtcatagc tggcgagcgg cggctgttcg ataaaatagc
    19981 gcgatcccgc cagattgagc gaccatgcct ggctgctgac ggtttgatcg cggtcgagta
    20041 cggcaaaacg caggttctcc acgtccatac tgatgccata gcccataatc agcatcagaa
    20101 ttaccgttcc cagcagcgcc agcgtcgagc gtaccggatc gcggcgtagc tccagcgctt
    20161 cgcggcgact gtagctgaac aaacgccgga agctcaatcc ctgccgcgac ggtttatctg
    20221 acgcggcggg cgtctgggat ggcggtattg gggtttcagg cgccgctccc gcagcttcct
    20281 gtagccagga aataaacgcc gcttccagat tggccgcgcc ccgctgttgc accaattcct
    20341 gcggcgtacc gctggcgagc actttaccgg cgtgcatcaa tgacattcgg tcgcaacgtt
    20401 ccgcttcgtt cataaaatgg gtcgagataa aaatcgtcac tttatcctga cgcgaaagat
    20461 cgaccataag ctgccagaac atatccctgg cgaccggatc aacgccggac gttggctcat
    20521 caagaatcag catttccggg cgatggatca ccgctaccgc caacgataaa cgctggcgga
    20581 taccgagcgg caacgaagcg gggagcgtat cttccacctc cgttagcata aagcgttcga
    20641 tcatctgcgc aacgcgcgcc gggatctccg ctggcggaat atgaaacagg cgggcatgaa
    20701 gttccagatt ctgccgcacg gtgagttcgt tatagagcga aaaagcctgc gacatatacc
    20761 cgacccggcg acgggtatcg atgtcgttcg ggtctaccgg ctggccaaat agccaggctt
    20821 ggccttcgct ggcgggaagc agaccggtca gcattttcat ggtggtcgat ttgccgcagc
    20881 cgtttgaacc gaggaagcca aaaatctcgc cgcgcggaat gcggaaatta acatggtcaa
    20941 ccgcgacgaa cttaccgaag cgcatggtca gatctttcgc ctcaatggca atctcttcct
    21001 gctcagcgtg atacggcggg atcaccactg gcttatgcgc ctggcgctgc gcttctggca
    21061 acagggcgat aaacgcctgc tccagcgtcg cgctatgggt ttttgcccgc agttgctgcg
    21121 cgctgccggt tgccagtatc tcgcccgcat tcatcgccac cagccagtca aaacgctccg
    21181 cctcttccat ataggccgtt gcgaccaaca cgctcatatt ggtctgccgt tggcggatac
    21241 tgtcgattaa gtcccagaac tgagcgcggg agagcgagtc cacgccggtg gtaggctcat
    21301 caagaatcag taattccggg tcatgaatca gcgcacagca cagccccagc ttttgtttca
    21361 tcccaccgga cagcttcccg gcaggacgat cacgaaacgg cgccaggccg gtgctgttca
    21421 gcagctcggt aatacgcgct tcgcgttcag ctttgtcatg accaaagaga cgagcgaaaa
    21481 aatcgacgtt ctcataaacc gatagcgtgt gataaaggtt tttccccagc ccctgcggca
    21541 tccaggcgat gcgcggacag acgtcgcggc gatgtttcgc atcgcgcata tcgccgccca
    21601 ggacgataac gttcccttgc tcaatcaccc gcgcgccaga aatcagcgac agcaggctcg
    21661 acttacccac cccgtccgga ccaatcagcc cgaccatact acgggcggga atgtccagcg
    21721 tgatattgtt cagcgcgacc gtttttccgt aatgctggct caccccctca agctgcgcca
    21781 cgggaggaac aggcaccagc gtcagcgacg tcattgcgac aacctcacgt tcagatcgtc
    21841 aggccagggc acgcgctcat ccagacgaac ccaggccatt cccggcaaac cggttttgac
    21901 atattccaga tgctgtcgca gcagctctgg cggaatacgc gctttgacgc ggaacatcag
    21961 cttcagccgt tcatcgtggg tttccacggt tttgggtgtg aactgcgcca cgctggcgac
    22021 aaaactgatg gtcgccggaa tacgcagatc cggcgcggcg tccagcacca gtcgcgcgtc
    22081 gccgccgatc ttcaacaacc ccgcctgttc ggtcggcagg aaaaatgtca tataaacatc
    22141 gctgagatcg accatgttca acacccggcc gccagccgat aacacttcgc ccggctccgc
    22201 aacgcggtac tgcacacgtc catcgcgcgg cgcttttaat tcgctgtcgt cgatgtcggc
    22261 gacaatacgc cgctcggtcg cctgcgccgc ttccacgcgc gtttgcgcct ggataatact
    22321 ggtacgcgcc gcctcaatcg ccgcttttgc cgcagatacc tgcgctttgg cggtctccag
    22381 ggcggcgcgc gcgctttccg ccgccgcgcg atcgtcatct aactgttgta cagataccgc
    22441 gccacgctgc gacagcgaac gagaacgcac gtgacgttta gagacggagt ccagctcagc
    22501 ttcccgctgt ttgacgaccg actgcgcggc gcgcatttca ctctggcgtt gctccagcaa
    22561 ggcacgggcg gcggcaactg cgctctcggc ctctttaatc tgcgcaatcg cctccagccg
    22621 ctgctcctgc aatacgcggg tatccatttt cgccagcacc tcgccctgac gaacgaactg
    22681 cccttccgaa acgaggatgg tatcaatacg cccggcaatc ttagtggcaa tatccacttc
    22741 ggtggcttca attctgccat tgctggcggc aaacccctcc ggtattcccg cagggcgcag
    22801 catccaccag gcgatcgcgg ccaccgccac aagaatcccc gctccccacc acaccagatg
    22861 acgcttcatt ttgtccataa tcgacccgcc gtaatccctg ttgcctaacc atgcgtgtca
    22921 caaagtccgc cgggcgtgcg ctcagcgggg gtttccatcc gggataagaa ggaatgaaaa
    22981 acaatggcca ttgagcgagc gttaaggcaa cgcgcgccgc gaaggaagtg aatgacgaaa
    23041 atgctgtgaa accgggtagt aatgttgtca tcatcagcgt tcctggccgg aaatgaaaca
    23101 cgcatactca taactgctgt ctattgaata ctaacacctg gattcaatat gtctattcgg
    23161 ttgtagcaca gatgttgcag acaaaaaatc gtgcccgtca atctatttac cgaaggggct
    23221 ggtaacgaaa gcatgcgtga ttacccctgc tcaagtcgcc gggcccggct aaaaaacatg
    23281 gatacagccc acggcatcaa atattcgtac ttctaataag gaaacgctcc tgccggaggt
    23341 aaaacacgat aatattttat ccactttcct gcccctattc tccgccctat tcagcatata
    23401 tgttgtcaga cagttacgtc ctgaaatata aaaatttata atttttataa aattacaacc
    23461 gtaaataatt aatgccccac acatatgtat aatttattat acatataact acatgatttt
    23521 aatgatatta aattagaaga gataattttt tatctttttt gcccactctg tgaagtgctt
    23581 cataatattc atgtgtataa aaaattatat tctcacatga acacttgttt cttatttatg
    23641 gacaggcgaa ggtttatgaa aacatccaat tttcaaaaat ggttgatggt cattcttctg
    23701 gcaatcggag gagggaccat ttttaaatcg atgtacctca gggaagtatt ttattacccc
    23761 tggaatgaat tcatgggagt gaataacacg gattcaggcc tgctgatgag ttggctgggg
    23821 tttgtgggga ttgtttcatc ttcaattgct ggggtgatta tcgataaggt gaacaatacc
    23881 cgactgatta tttcttttac ctttctggct gtgggcgtaa ccacattatg gcagtcaaca
    23941 gcaccgggtc tggctacgca gtatgtcatc atcggcatac tatctttcct cgcaaatggt
    24001 cttttcctag tatcgatggt gcgcgcaacc cgcctgattg gtaatgccag tgaccagggg
    24061 aagctgtttg gtttcctgga gtccggacgt ggtatcgctg ggtcagccat ctctgccgtt
    24121 gccgtagcat ggttcgccat gtctgcaacc gaagtggaag ggattggcag tgtgctacat
    24181 gcatacggct ttctctacct agcgctgggt gttctgatgt ggttcgccat gccccgtgat
    24241 aaccataatt ctgcttccgg agaagaaaag gccaaggaaa aaatatctgt acacgatatt
    24301 ctggctgtca tgaaggttaa ggaagtctgg tttgcagctt tctccatctt tgcaaccatc
    24361 tccttctatc aggggtcctc atatctggtt ccttatctgt ctgatgtcta cggaatgacc
    24421 gccgaacatg ccggaattat cggtatgatc cgtgcttatg tcctcgctat cctgattgca
    24481 ccggttgtgg gtctgctcgc agacaaagtc ggctcagcga ttaaggtgat gaattggctg
    24541 tttattgccg gggtgattgg tgtcgccatg ttcctggtga tcccacagga tccggctatg
    24601 gtatgggtcc tgatcggcac cctgatgatt gtaggctcca ttaactttgc tctgcgcggg
    24661 atcatgtatg cgcaaattga ggaaatgaag gttcctgttc gtctgaccgg taccgttatg
    24721 gggatcatgg ccactgtggg attctctccg gaaatgttta tccatgcgtt attcgggtac
    24781 tggcttgatg catataaagt acagggttac acctacatgt ttatcttcat gggtgccatg
    24841 tttgctctcg ctgtattcac ttcactttta cttctccgca atgccaaaac ggcatttaag
    24901 aaaa
//
LOCUS       DAJVBX010000047        24491 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.047, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000047 DAJVBX010000000
VERSION     DAJVBX010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 24491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24491
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.047"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            21..935
                     /gene="pocR"
                     /locus_tag="OPV72_001662"
     CDS             21..935
                     /gene="pocR"
                     /locus_tag="OPV72_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory protein PocR"
                     /protein_id="HCR9914001.1"
                     /translation="MISASALNSELINKIAQDFAQATTGLAVVVVNIHGDEISELFNF
                     TPFCQLMRQHPQHSTRCRMSDRCGGLEASKSDQPCIYRCHAGLTDFSIPLVIAGHLVG
                     FVLCGQVRLSNDVELVNILNVDDRWQADPELLNEFRNVPEMDYSRVIASADLLKLIVE
                     NCLKKQLNFVVIKDNPQQSEANKTTRGPTPHDSKMKKALRYIDAHLSDDLRLEDVASH
                     VYLSPYYFSKLFKKYQGIGFNAWVNRQRMVSARELLCHSDWSIASIARNLGFSQTSYF
                     CKVFRQTYQVTPQAYRQQINENSHPPSI"
     regulatory      1261..1436
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            1556..2911
                     /locus_tag="OPV72_001663"
     CDS             1556..2911
                     /locus_tag="OPV72_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008785142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyrinate a,c-diamide synthase"
                     /protein_id="HCR9914002.1"
                     /translation="MLAGTGSGCGKTTVTLGLLRLLQKRALRVQPFKVGPDYLDTGWH
                     TAICGVASRNLDSFMLPPPVLNALFCEQMRQADIAVIEGVMGLYDGYGVDPNYCSTAA
                     MAKQLGCPVILLVDGKAVSTSLAAIVMGFQHFDPTLNLAGVIVNRVTSDAHYQLLKNA
                     IEHYCSLPVLGYVPPCDGVALPERHLGLITARESLVNQQSWHDFAATLEQTVDVDALL
                     SLSLLSALPAGMWPERPDNTAGAGLTLALADDEAFNFYYPDNIDLLERAGVNIVRFSP
                     LHDRALPDCQMIWLGGGYPELYAADLAANTAMLKHLRAAHQRGVAIYAECGGLMYLGS
                     TLEDSGGEIHQMANIIPGHSKMGKRLTRFGYCEAQAMQPTLLAVPGEIVRGHEFHYSD
                     FIPETPAVMACRKVRDGRVLQEWTGGWQTGNTFASYLHVHFAQRPEMLQHWLAAARRV
                     L"
     gene            2908..3867
                     /locus_tag="OPV72_001664"
     CDS             2908..3867
                     /locus_tag="OPV72_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HCR9914003.1"
                     /translation="MTILAWCIAWVLDFIIGDPQHWPHPVRWIGRLITFVQRIVRRYC
                     PGDKALRIGGGVMWVVVVGVTWGVAWGVLALAQRIHPWFGWSVEVWMIFTTLAGRSLA
                     RAAQEVERPLRENDLAESRIKLSWIVGRDTSQLQPAQIYRAVVETVAENTVDGIIAPL
                     FFLFLGGAPLAMAYKAVNTLDSMVGYKHEKYRAIGMVSARMDDVANYLPARLSWLLLG
                     IAAGLCRLSGWRALRIGWRDRYNHSSPNCAWSEACVAGALGIQLGGPNNYFGERVDKP
                     WIGDAQRGISVDDISRTIRLMWVASTLALALFIAARCGLSGVA"
     gene            3878..4357
                     /locus_tag="OPV72_001665"
     CDS             3878..4357
                     /locus_tag="OPV72_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-8X methylmutase"
                     /protein_id="HCR9914004.1"
                     /translation="MHYIQQPQTIEANSFTIISDIIRETRPDYRFASPLHEAIIKRVI
                     HTTADFDWLDILWFSADALEQLCDALRQPCIIYTDTTMALSGINKRLLATFGGECRCY
                     ISDPRVVGVPVGFVGAAESKEALTHSHFPAVAALGRKGGSNVAAAIVNALLYHLREA"
     gene            4357..5496
                     /locus_tag="OPV72_001666"
     CDS             4357..5496
                     /locus_tag="OPV72_001666"
                     /EC_number="2.1.1.195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-5B (C(1))-methyltransferase"
                     /protein_id="HCR9914005.1"
                     /translation="MSELSFDAPVWRHGKALRKGYTTGSCATAAAKVAELMVLRQHLI
                     HQVSIVTPSGVTLCLNVESPHIEGQQAIAAIRKDGGDDVDATHGMLIFARVTLNDSGE
                     ITLTGGEGIGTVTRKGVGLPLGSAAINRTPRHTIESAVREAIGPARGADVEIFAPEGE
                     VRAQKTYNSRLGILGGISIIGTTGIVTPMSEESWKRSLSLELEIKRASGLTRVILVPG
                     NHGERFVREQMGVDTQAVVTMSNFVGYMIEEAVRLGFCQIVLVGHPGKLIKIAAGIFH
                     THSHIADARMETLVAHLALLGAPLELLTLVGDCDTTEAAMEHIEAYGFGHIYNHLARR
                     ICLRVMQMLRFTKTPPVCDAILFSFDNHILGSNRPVDEIAKELQC"
     gene            5490..6095
                     /locus_tag="OPV72_001667"
     CDS             5490..6095
                     /locus_tag="OPV72_001667"
                     /EC_number="2.1.1.289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-7 (C(5))-methyltransferase"
                     /protein_id="HCR9914006.1"
                     /translation="MLTVVGMGPAGRHLMTPAALEAIDHADALAGGKRHLAQFPAFGG
                     ERFTLGADIGALLSWIAARRDKGIVVLASGDPLFYGIGTRLVAHFGIEQVRIIPGISA
                     VQYLCAQAGIDMNDMWLTSSHGRCVSFEQLANHRKVAMVTDARCGPREIARELVARGK
                     GHRLMVIGENLAMENERIHWLPVSAVNADYEMNAVVILDER"
     gene            6085..6663
                     /locus_tag="OPV72_001668"
     CDS             6085..6663
                     /locus_tag="OPV72_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating cobalt-precorrin-6B
                     (C(15))-methyltransferase"
                     /protein_id="HCR9914007.1"
                     /translation="MKDELFLRGENVPMTKEAVRALALSKLELHRASHLIDVGAGTGS
                     VSIEAALQFPSLQVTAIERNPAALRLLDENRQRFACGNIDILPGEAPMTITGKADAVF
                     MGGSGGHLTALIDWAMGHLHPGGRLVMTFILQENLHSALAHLVHIGACRMDCVQLQLS
                     SLTPLGAGHYFKPNNPVFVIACQKEENHVRDI"
     gene            6647..7420
                     /locus_tag="OPV72_001669"
     CDS             6647..7420
                     /locus_tag="OPV72_001669"
                     /EC_number="2.1.1.271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-4 methyltransferase"
                     /protein_id="HCR9914008.1"
                     /translation="MSETFDPRCVWFVGAGPGDRELITLKGYRLLQQAQVVIYAGSLI
                     NTELLDYCPAQAERYDSAELHLEQIIELMAAGVKAGKTVVRLQTGDVSLYGSVREQGE
                     ELTRRGIDWQVVPGVSAFLGAAAELGVEYTVPEVSQSLIITRLEGRTPVPAREQLEAF
                     ASHQTSMAIYLSVQRIHRVAERLIAGGYPATTPVAVIYKATWPESQTVRGTLADISDK
                     VRDAGIRKTALILVGNFLGKEYHYSRLYAADFSHEYRKA"
     gene            7401..8456
                     /gene="cbiG"
                     /locus_tag="OPV72_001670"
     CDS             7401..8456
                     /gene="cbiG"
                     /locus_tag="OPV72_001670"
                     /EC_number="3.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin 5A hydrolase"
                     /protein_id="HCR9914009.1"
                     /translation="MNTVKPESIALFCLTPGGVALAKRLAAMLPLTCFTSEKLREEGF
                     IPFDGGFANTARQAFTTYTALIFIGATGIAVRVLAPLVNDKFSDPAVVVIDERGQHVI
                     SLLSGHAGGANALTRYLAGMLGADPVITTATDVNEMSALDTLAFQLNARMSDLRTAVK
                     TVNQMLVSHQRVGLWWDAELTEEIGQCDIRGFIPVDDLQRLPELDALICVSLRNDLPE
                     LPVLHWKLVPQRVVAGIGCRRDTPFPLLATLLARQLEAQKLDPLALKAIGSVTLKKGE
                     PGLIQLASCCRVPFKTFTAEALREFEHHFPGSGFVRKTVGVGSVSGPAAWLLSQGQLL
                     GETLREQGVTITLGVSH"
     gene            8456..9181
                     /locus_tag="OPV72_001671"
     CDS             8456..9181
                     /locus_tag="OPV72_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-3B C(17)-methyltransferase"
                     /protein_id="HCR9914010.1"
                     /translation="MLSVIGIGPGSQAMMTMEAIEALQAAEIVVGYKTYTHLVKAFTG
                     DKQVIKTGMCKEIERCQAAIELAQAGHNVALISSGDAGIYGMAGLVLELVSKQKLDVE
                     VRLIPGMTASIAAASLLGAPLMHDFCHISLSDLLTPWPVIEKRIVAAGEADFVICFYN
                     PRSRGREGHLARAFDLLAASKSAQTPVGVVKSAGRKKEEKWLTTLGDMDFEPVDMTSL
                     VIVGNKTTYVQDGLMITPRGYTL"
     gene            9178..9917
                     /locus_tag="OPV72_001672"
                     /pseudo
     CDS             9178..9917
                     /locus_tag="OPV72_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460971.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-6A reductase"
     gene            10036..10764
                     /locus_tag="OPV72_001673"
     CDS             10036..10764
                     /locus_tag="OPV72_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001726449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sirohydrochlorin cobaltochelatase"
                     /protein_id="HCR9914011.1"
                     /translation="MACERDLAESCPDRDLFRAFTSGMIIRKLRQRDGIDIDTPLQAL
                     QKLAAQGYQDVAIQSLHIINGDEYEKIVREVQILRPLFTRLTLGVPLLSSHNDYVQLM
                     QALRQQMPSLRQTEKVVFMGHGASHHAFAAYACLDHMMTAQRFPARVGAVESYPEVDI
                     LIDSLRDEGVTGIHLMPLMLVAGDHAINDMASDDGDSWKMRFNAAGIPATPWLSGLGE
                     NPAIRAMFVAHLHQALNMAVEEAA"
     gene            10761..11474
                     /locus_tag="OPV72_001674"
     CDS             10761..11474
                     /locus_tag="OPV72_001674"
                     /EC_number="2.1.1.151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-factor II C(20)-methyltransferase"
                     /protein_id="HCR9914012.1"
                     /translation="MNGKLYALSTGPGAPDLITVRAARILGSLDILYAPAGRKGGDSL
                     ALSIVRDYLGEQTEVRCCHFPMSADGAEKEAVWNEVAAALTAEVEAGKQVGFITLGDA
                     MLFSTWIFLLQRIGCPEWLEIVPGVTSFAAIAARAKMPLAIERQSLAVISCTAPEAEI
                     AQALQQHDSLVLMKVYGRFARIKALLAQAGLLECALMMSEATLPGEQCWRHLHEVNDD
                     RALPYFSTILVNKQWEYAE"
     gene            11471..12207
                     /gene="cbiM"
                     /locus_tag="OPV72_001675"
                     /pseudo
     CDS             11471..12207
                     /gene="cbiM"
                     /locus_tag="OPV72_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460968.3"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ECF transporter S component CbiM"
     gene            12209..12490
                     /locus_tag="OPV72_001676"
     CDS             12209..12490
                     /locus_tag="OPV72_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     substrate-binding protein"
                     /protein_id="HCR9914013.1"
                     /translation="MKKTLMLLAMVVALVILPFFINHGGEYGGSDGEAESQIQALAPQ
                     YKPWFQPLYEPASGEIESLLFTLQGSLGAAVIFYILGYCKGKQRRDDRA"
     gene            12477..13154
                     /locus_tag="OPV72_001677"
     CDS             12477..13154
                     /locus_tag="OPV72_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     transmembrane protein"
                     /protein_id="HCR9914014.1"
                     /translation="MTGLDRLSYQSRWAHVAPQRKFLLWLAMMILAFVLPPVGQGIEL
                     LIIAGLSCWLLRISLWRWCRWMAIPFGFLLVGVITIIFSISREPQMLLAGISVGPYWI
                     GITRAGVVTANETFWRSLTALSATLWLVMNLPFPQLISLLKRAHIPRLLTEQILLTWR
                     FLFILLDEAVAIRRAQTLRFGYCSLPNGYRSLAMLTGLLFTRVLMRYQQMTTTLDIKL
                     YQGDFHL"
     gene            13163..13978
                     /locus_tag="OPV72_001678"
     CDS             13163..13978
                     /locus_tag="OPV72_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HCR9914015.1"
                     /translation="MLATSDLWFRYQDEPVLKGLNLDFSLSPVTGLVGANGCGKSTLF
                     MNLSGLLRPQKGAVLWQGKPLDYSKRGLLALRQQVATVFQDPEQQIFYTDIDSDIAFS
                     LRNLGVPEAEITRRVDEALTLVDAQHFRHQPIQCLSHGQKKRVAIAGALVLQARYLLL
                     DEPTAGLDPAGRTQMIAIIRRIVAQGNHVIISSHDIDLIYEISDAVYVLRQGQILMHG
                     APGEVFACTEAMEHAGLTQPWLVKLHTQLGLPLCKTETEFFHRMQKCAFREAS"
     gene            13975..15495
                     /locus_tag="OPV72_001679"
     CDS             13975..15495
                     /locus_tag="OPV72_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyric acid synthase"
                     /protein_id="HCR9914016.1"
                     /translation="MTQAVMLQGTASDVGKSVLVAGLCRIFYQDGLRTAPFKSQNMAL
                     NSGITPDGKEMGRAQIFQAEAAGITPDVRMNPVLLKPTSDRQAQVVLMGKVATNMDAV
                     SYHDYKPRLREQILAVYNSLAQEYDVIVLEGAGSPAEINLRDRDIVNMGMAEMAQCPV
                     ILVADIDRGGVFAAIYGTLALLHKQERDRVKGVIINKFRGDVALLYSGIEQIESLTGV
                     PVLGVMPWLDVDLEDEDGVALQNDKYRGNAPRDITIAIVQLPHISNFTDFNALAAQPD
                     VRIRYIRRPEALTDADLVILPGSKNTLSDLAWLRESGMADAVLQTHRQGVPVMGICGG
                     YQMLGDTIVDEVESGLGTQPGLGLLNTITRFAQDKTTTQVNATMSGELPGWLAAAAGL
                     PVRGYEIHMGETVLQEGCCTAMTLQKNGCSVADGAVTADGLAFGTYLHGLFDSDAFTR
                     AVVNGLRARKGLAPWETTFCYAEHKARQFDLLAEAMRQHIDIDKIYTIMQQHQEPV"
     gene            15492..16037
                     /gene="cobU"
                     /locus_tag="OPV72_001680"
     CDS             15492..16037
                     /gene="cobU"
                     /locus_tag="OPV72_001680"
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="HCR9914017.1"
                     /translation="MMILVTGGARSGKSRHAEALISDAPQVLYIATSQILDDEMAARI
                     QHHKDGRPAHWRTAECWRHLDTLITADLAPDDAILLECITTMVTNLLFALGGENDPEQ
                     WDYAAMERAIDDEIQILIAACQRCPAKVVLVTNEVGMGIVPENRLARHFRDIAGRVNQ
                     RLAAAADEVWLVVSGIGVKIK"
     gene            16034..16777
                     /gene="cobS"
                     /locus_tag="OPV72_001681"
     CDS             16034..16777
                     /gene="cobS"
                     /locus_tag="OPV72_001681"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HCR9914018.1"
                     /translation="MSKLFWAMLAFISRLPVPSRWSQGLDFEQYSRGIVMFPFIGLIL
                     GGISGLIFILLQPWCGIPLAALFCILALALLTGGFHLDGLADTCDGIFSARRRERMLE
                     IMRDSRLGTHGGLALIFVLLAKILVVSELALRGTPMLAALAAACAAGRGSAVLLMYRH
                     RYAREEGLGNVFIGKVSGRQTCITLGLAVIVATVLLLGMQGLATMVVTLAAIFILGQL
                     LKRTLGGQTGDTLGAAIELGELIFLLALL"
     gene            16804..17874
                     /gene="cobT"
                     /locus_tag="OPV72_001682"
     CDS             16804..17874
                     /gene="cobT"
                     /locus_tag="OPV72_001682"
                     /EC_number="2.4.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /protein_id="HCR9914019.1"
                     /translation="MQTLHALFRDIPAPDAEAMARAQQHIDGLLKPPGSLGRLETLAV
                     QLAGMPGLNGTPQVGEKAVLVMCADHGVWDEGVAVSPKIVTAIQAANMTQGTTGVCVL
                     AAQAGAKVHVIDVGIDAEPIPGVVDMRVARGCGNIAVGPAMSRSQAEALLLEVSRYTC
                     DLAKRGVTLFGVGELGMANTTPAAAMVSVFTGSDAKEVVGIGANLPPSRIDNKVDVVR
                     RAIAINQPNPRDGIDVLSKVGGFDLVGMTGVMLGAARCGLPVLLDGFLSYSAALAACQ
                     IAPAVRPYLIPSHFSAEKGARIALAHLSMEPYLHMAMRLGEGSGAALAMPIVEAACAM
                     FHNMGELAASNIVLPEGNANAT"
     gene            17952..18881
                     /gene="ldtA"
                     /locus_tag="OPV72_001683"
     CDS             17952..18881
                     /gene="ldtA"
                     /locus_tag="OPV72_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HCR9914020.1"
                     /translation="MRRITPFFPFFVLLVSHFSLAISYPLPPEGSRLVGQPVTIAVPQ
                     NNTQPLESFAARYGQGLSNMLEANPGVDVFLPQSGSTLVVPQQLILPDTVREGIVVNV
                     AEMRLYYYPAGTNTVEVLPIGIGQAGRETPRNWVTAVERKQDGPVWVPTANTRREYAK
                     EGKTLPAMVPAGPDNPMGLYAIYIGRLYATHGTNANFGIGLRVSQGCIRLRNDDIKYL
                     FDHVPVGTRVQIIDRPVKFSVEPDGSRWLEVHEPLSRNRAEFESDKKVPLPVTPVLRT
                     FIKGDDVDTSRVNEVLERRSGMPVNISAGRSGL"
     gene            complement(19107..19182)
                     /locus_tag="OPV72_001684"
     tRNA            complement(19107..19182)
                     /locus_tag="OPV72_001684"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19147..19149),aa:Asn,seq:gtt)
     gene            19342..20799
                     /locus_tag="OPV72_001685"
     CDS             19342..20799
                     /locus_tag="OPV72_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EmmdR/YeeO family multidrug/toxin efflux MATE
                     transporter"
                     /protein_id="HCR9914021.1"
                     /translation="MWFQLSSLRSILNVSTALRQVVVRTPWYAKRKSYKVLFWREITP
                     LAIPIFLENTCVLLMGVLSTFLVSWLGKEAMAGVGLADSFNMVIMAFFAAIDLGTTVV
                     VAFSLGKRDRRRARAAARQSLVIMTLFAVVLAVVIHYFGSEIINIVAGEATPEVKGLA
                     LTYLELTVLSYPAAAIALIGSGALRGAGNTKIPLMINGGMNILNIVISSILIYGAFSW
                     QGLGFAGAGLGLTISRYIGAVAIIWVLMIGFNPALRIPLKSYLKPLNFGIIWEVMGIG
                     IPASIESVLFNGGKLLTQMFVAGMGTNVIAGNFIAFSVAALINLPGNALGSASTIITG
                     KRLGTGQIGQAERQLRHVFWMSTIVLTAIAWGTAPFAGLFASFYTQEQDVKEVVKVLL
                     WLNAAFMPIWAAAWVLPSGFKGARDVRFAMWVSMLGMWGCRVVAGYTLGIVLGMGVVG
                     VWLGMFLDWAVRGALFYWRLISGRWLWRYPRVKRE"
     gene            20940..21015
                     /locus_tag="OPV72_001686"
     tRNA            20940..21015
                     /locus_tag="OPV72_001686"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20973..20975,aa:Asn,seq:gtt)
     gene            21436..21899
                     /locus_tag="OPV72_001687"
                     /pseudo
     CDS             21436..21899
                     /locus_tag="OPV72_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002211098.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            21893..22219
                     /locus_tag="OPV72_001688"
     CDS             21893..22219
                     /locus_tag="OPV72_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1493 family protein"
                     /protein_id="HCR9914022.1"
                     /translation="MLDNIEQQVYELVRPYAGTYLFNIKQVELTPEIDLDTDLSIDEL
                     EAEDLMNKFFEKLNVERGNFRIETYFPNHPFSWHPFKKTEPVPVPDFTISMLIESAKA
                     GKWLYD"
     gene            complement(22208..22369)
                     /locus_tag="OPV72_001689"
     CDS             complement(22208..22369)
                     /locus_tag="OPV72_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_448416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HCR9914023.1"
                     /translation="MTAKEETKGVSVRAAAVNMNPLKRKENYLSATIIAQKEGYWYSH
                     LLSSLQLVI"
     gene            22415..23869
                     /locus_tag="OPV72_001690"
     CDS             22415..23869
                     /locus_tag="OPV72_001690"
                     /EC_number="3.2.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP nucleosidase"
                     /protein_id="HCR9914024.1"
                     /translation="MENKGTNLTPEQALDRLEELYEQSVNALREAIADYVDNGTLPDP
                     HARLNGLFVYPSLSVSWDGATPNPPKTRAFGRFTHPGCYTTTVTRPALFRAYLLEQLN
                     LVYHDYGAHIAIEASHHEIPYPYVIDGSALTLDRSMSAGLTRHFPTTELAQIGDETAD
                     GLFHPGEFYPLSHFDARRVDFSLARLRHYTGTPVEHFQPFVLFTNYTRYVDEFVRWGC
                     SQILDPDSPYIALSCAGGIWITAETEAPEEAISDLAWKKHQMPAWHLVTADGQGITLV
                     NIGVGPSNAKTICDHLAVLRPDVWLMIGHCGGLRESQAIGDYVLAHAYLRDDHVLDAV
                     LPPDIPIPSIAEVQRALYDATKAVSGMPGEEVKQRLRTGTVVTTDDRNWELRYSASAL
                     RFNLSRAVAIDMESATIAAQGYRFRVPYGTLLCVSDKPLHGEIKLPGQANRFYEGAIS
                     EHLQIGIRAIDLLRAEGDRLHSRKLRTFNEPPFR"
     gene            23959..24237
                     /locus_tag="OPV72_001691"
     CDS             23959..24237
                     /locus_tag="OPV72_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000600594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914025.1"
                     /translation="MILHPAKALLCRGFITIAGDLSPIIASTSGNAPEGENIAPHFTL
                     LERLDPQARINKQIPTVRIDQLKGIIRRLDTEDFRVGQGYRVVTPLSN"
BASE COUNT         5254 a         6020 c         7178 g         6039 t
ORIGIN      
        1 attaactgag gggttttatc atgatttctg cgagcgctct gaactcagaa ctcattaata
       61 aaatcgcaca ggattttgca caagccacca ccggtctggc ggttgtggtt gtcaatattc
      121 atggtgatga aatatctgag ctattcaatt tcacgccgtt ttgtcagttg atgcggcagc
      181 atccccagca tagtacacgt tgtcgtatga gcgatcgctg cgggggactg gaggcatcga
      241 agtccgatca accctgtatt tatcgttgtc atgccggtct aacggatttt tctattccgc
      301 tggtaatcgc agggcattta gttggctttg ttttatgcgg gcaggttcgt ttaagtaatg
      361 acgtggagct ggtaaacatt cttaatgtcg acgatcgctg gcaggctgac cctgagctct
      421 tgaatgaatt tcggaatgtg ccagagatgg actattcacg cgttatcgct tccgccgatc
      481 ttcttaaact gatagttgag aattgcctga aaaaacagct caatttcgtg gttatcaaag
      541 acaatccgca gcaatcggag gcaaataaaa ccactcgtgg ccccactccg catgacagta
      601 aaatgaaaaa agcgcttcgc tatattgatg cgcatttgtc cgacgatctt cgtcttgagg
      661 atgtcgcctc acatgtctat ctcagcccct attacttcag taagctattc aagaaatatc
      721 agggaatcgg atttaatgcg tgggtgaacc gccagagaat ggttagcgcc agagaattgc
      781 tttgccatag tgactggagt attgccagta ttgcgcgtaa tttaggcttt tcgcaaacca
      841 gttatttttg caaagtcttc cgccagacct atcaggttac gccgcaggct tatcgtcagc
      901 agataaatga gaattctcat cctccatcga tataaatagc aatattttgc tattgccgat
      961 ttttgatagt gttttgtatc ttaatcattt cagaaagaaa atttatctgg tgtaacaata
     1021 aattgtcata gcgcaacaaa ataataaaat ttagggcata aactgcacca gtttttattt
     1081 ttgtgatgaa gtacagtgtc aggaaagata agttttatta cgctttgtcg atacgtttta
     1141 tcgtcaatat accggtaagg atgagtagat taacgtcaga tgagcaaccg ctcaggctat
     1201 tgctcacaga aatgtaaaac gtagcacatt attaattgcc gttatgggtg tgccgtacag
     1261 ccataacgta aaccaacagg tttgccacat ttgtggtagg gaagggggtg aaaatccccc
     1321 gcagcccccg ctgctgtgat gctgacgacc ccgtaaagac cactgatcgc aagattggga
     1381 aggacgggcg aggaggacgc taagccagaa gacctgcctg tcggtgataa ccaacaactt
     1441 cggtgggaag tgggttgcga agacgcgtac agtcgaaaga ctgaacatgc gcgtacctgt
     1501 atacccctac caccctgaac aggatcaggg taatggcggc aaggcatcac gctttattct
     1561 tgcaggcaca ggaagcggtt gcggcaaaac cacggtgacg cttggtttgt tgaggctgct
     1621 gcaaaaacgc gcgctgcgcg tacagccgtt taaagttggg ccagattacc ttgataccgg
     1681 ctggcatacc gctatctgtg gcgtggcgtc ccgtaatctt gacagtttca tgcttcctcc
     1741 tcctgttctc aacgccttat tttgcgaaca aatgcggcag gcggatatcg ctgtcattga
     1801 aggcgtcatg gggctgtatg acggctatgg cgtcgacccc aattactgca gcacagccgc
     1861 gatggccaaa cagcttggtt gcccggtcat cctactggtg gacggcaagg ctgtttcaac
     1921 gtcgcttgcg gctatcgtta tgggatttca gcacttcgac ccgaccctca acctcgcggg
     1981 cgtgattgtg aatcgcgtca ctagcgacgc ccactatcag ctcctcaaaa atgccattga
     2041 acattattgc tcactgccgg tactggggta tgtccctcct tgcgacggcg tcgcattacc
     2101 tgaacgccac ctggggttga ttaccgccag agaatccctc gtcaatcagc aatcatggca
     2161 tgattttgcc gccacgctgg aacaaacagt ggatgtggat gcgctactct cgctgagcct
     2221 gttatcagcg cttccggcgg gaatgtggcc tgaacgcccc gataacacag cgggggcagg
     2281 gctgacgctt gctctggcgg atgatgaggc ctttaacttt tattaccccg ataacatcga
     2341 tttgctggag cgtgccggcg ttaacattgt gcgttttagc ccactgcatg accgcgcatt
     2401 gcctgattgt cagatgatct ggctgggcgg tggatatcct gaattatacg ccgcggatct
     2461 ggcggcaaat acggcgatgt taaaacattt gcgggcggcg catcagcgcg gcgtggcgat
     2521 ttacgcggag tgtggcggtc tgatgtatct ggggagcact ctggaggata gcggcgggga
     2581 aattcatcag atggcgaata ttatccccgg tcacagcaaa atgggtaagc gacttacccg
     2641 ctttggttac tgtgaggcgc aggctatgca gccaacgcta ttggcggtgc ctggcgagat
     2701 agtgcgcggc catgaatttc actactcaga ttttatcccc gaaacacccg ccgttatggc
     2761 ctgtcgtaag gttcgcgatg gccgcgtgtt acaagaatgg actggcggct ggcagacagg
     2821 caacacgttt gccagctatc tgcacgtcca tttcgcccag cgtccggaaa tgttgcagca
     2881 ctggctggcg gcggcgaggc gagtattatg acgatccttg cctggtgtat cgcctgggtg
     2941 ctggatttta tcatcggcga ccctcaacac tggccccatc cggtacgctg gataggccga
     3001 ttaattacgt ttgtgcagcg tattgtgcgt cgctattgtc ccggcgataa agcgctgcgg
     3061 attggcggcg gcgtaatgtg ggttgtggtt gtcggggtga cctggggcgt ggcatggggc
     3121 gtactggcgc tggcgcagcg gattcacccc tggtttggct ggagcgtcga agtctggatg
     3181 atctttacca cgctggccgg acgctctctg gcccgcgccg cgcaggaggt tgaacgaccg
     3241 ttgcgggaga acgaccttgc ggaaagccga ataaaactct cctggatcgt cgggcgcgat
     3301 acgtcgcaac ttcagccagc gcagatctat cgcgccgtgg tggaaacggt tgcagaaaac
     3361 accgttgacg gcattatcgc gccgctcttt ttcctctttc tcggcggcgc gccgctggcg
     3421 atggcctaca aagccgtcaa taccctggat tcaatggtgg gctacaaaca tgaaaaatac
     3481 cgggcgattg gtatggtcag cgcccgtatg gacgacgtag cgaactattt gcccgcccga
     3541 ctgagctggc tgttgctggg cattgcggca ggactgtgtc gcctgagtgg ttggcgggcg
     3601 ctgcgtattg gctggcgtga ccgttataac cacagtagcc caaattgcgc ctggtcggaa
     3661 gcgtgtgtgg ctggcgcctt aggaatccag ctcggtggcc caaataacta ctttggcgag
     3721 cgtgtggaca agccctggat cggcgacgcg cagcgcggta tttccgtgga cgatatttcc
     3781 cgaacgattc gattgatgtg ggtcgcttca accctggcgc tggcgctgtt tattgcggcg
     3841 cggtgcgggt tatctggcgt ggcctgagga cgacagtatg cattatatcc agcagcccca
     3901 aaccattgag gccaacagtt tcaccattat tagcgacatt attcgcgaaa cgcgtcctga
     3961 ttaccgtttc gccagtccgc tccatgaggc cattatcaag cgggttattc ataccaccgc
     4021 cgatttcgac tggctggaca ttttgtggtt ctctgccgat gcgctggagc agctttgtga
     4081 tgcgctacgc caaccgtgca ttatttatac cgataccacg atggcgctgt ccggcattaa
     4141 taaaagatta ctggcgacgt ttggcggcga gtgtcgctgt tatatcagcg atccgcgcgt
     4201 ggtgggcgta ccggtaggct ttgtcggcgc ggcggagtcc aaagaggcgc tcacccatag
     4261 ccattttccc gcggttgccg cgttagggcg taaaggcggc agtaacgtgg ctgccgctat
     4321 cgtcaatgcg ctgctctatc acctccggga ggcctgatga gcgagctttc ttttgacgcg
     4381 ccggtctggc gccacggtaa agcgttacgt aaaggatata ccaccggttc ctgcgcgacg
     4441 gcggcggcaa aagtcgccga gctgatggta ttacgtcaac atctgattca tcaggtctcc
     4501 atcgtcacgc cgtcgggcgt cacgctatgc ctgaacgtgg agtcgccgca cattgaaggc
     4561 cagcaggcga tagccgcaat tcgtaaagat ggcggcgatg acgtggatgc cacgcacggg
     4621 atgctgattt ttgcccgcgt tacgctcaac gacagcggtg agattacgct cactggcggc
     4681 gaaggtattg gtacggtaac gcgtaaaggg gttggactgc cgctcgggag cgctgccatc
     4741 aatcgtacgc cgcgccatac cattgaatct gcggtgcgcg aagcgatagg cccggcgcgt
     4801 ggggctgatg tggagatttt tgccccggaa ggcgaagtgc gggcgcagaa aacctataac
     4861 tcgcggcttg gcattcttgg cggcatttcc attattggca ctaccggtat tgtgacgccg
     4921 atgtcggaag aaagctggaa acgctcgcta tcgctggaac tggagatcaa acgggcgtca
     4981 ggattaacgc gggtgatact cgtgccgggc aaccacggcg aacggtttgt tcgcgaacaa
     5041 atgggcgtcg acacacaggc ggtcgtcacc atgagcaatt ttgtcggcta catgattgaa
     5101 gaggcggtac ggctgggatt ttgccagata gtgctggtgg gtcatcctgg aaaattgatc
     5161 aaaatcgccg ccgggatctt tcatacccat agccatatcg ccgatgcgcg catggaaacg
     5221 ctggtcgcgc atttagcttt actgggcgcg ccgctggagt tactcaccct ggtcggcgat
     5281 tgcgatacca ctgaagcggc aatggagcac attgaagcat atggcttcgg gcatatctat
     5341 aaccatcttg ccaggcgtat ttgtttgcga gtcatgcaga tgctgcgttt taccaaaacg
     5401 ccgcctgtct gcgacgccat cctgttttct tttgataacc atattctcgg cagtaatcgt
     5461 cccgtcgacg agattgctaa ggagctgcaa tgctaacggt cgtgggaatg gggcccgctg
     5521 gacggcattt gatgacgcct gcggcgctgg aagcgataga ccacgccgat gcgctggcag
     5581 gcggtaaacg gcatttggcg cagtttccgg cgtttggcgg cgaacgattt acgctgggcg
     5641 cggatattgg cgcgttgttg tcatggattg ccgcccgtcg ggataaaggg atcgtggtgc
     5701 tggcctccgg cgatccgctg ttttatggca tcggtacacg cctggtggcg cattttggta
     5761 tcgaacaggt tcgcattatc cctggcatca gcgccgtaca gtatctgtgc gcacaggctg
     5821 gaattgatat gaatgacatg tggttgacca gtagccacgg tcgttgcgtc agcttcgagc
     5881 agttggcgaa ccatcgcaaa gtggcgatgg tcacggatgc ccgctgcggg ccgcgggaaa
     5941 tcgcgcggga actggtcgcg cgtggtaaag ggcatcgctt gatggtgatt ggtgaaaatc
     6001 tggcgatgga aaatgagcgg atccactggc tacccgtcag tgcggtcaac gccgactatg
     6061 aaatgaatgc agtggtgatc ctggatgaaa gatgagcttt ttctgcgcgg cgagaacgtg
     6121 ccaatgacca aagaggcggt acgggcgctg gcactgtcga aacttgagct ccaccgcgcc
     6181 agtcacctga ttgacgtcgg ggcgggaacg ggaagcgtct caattgaagc ggcgctgcaa
     6241 tttccttcgt tgcaggtgac ggctattgag cgtaatcctg ccgcgctacg gctgcttgat
     6301 gagaatcgtc agcgctttgc ctgcggcaat atcgatattc tccccggcga agcgccaatg
     6361 accataaccg ggaaagccga tgcggtgttt atgggcggca gcggcgggca tctgacggcg
     6421 ctgattgact gggcgatggg ccatctgcat cccggtggcc gtctggtgat gacctttatc
     6481 ttgcaggaaa acctccatag cgcgctggcg catcttgtgc acatcggcgc atgccgaatg
     6541 gactgtgtac agcttcagct ttcatcgtta acgccgctgg gggcgggaca ctatttcaaa
     6601 ccgaacaacc ctgtttttgt tatagcctgt cagaaggaag aaaaccatgt cagagacatt
     6661 tgatccacgc tgtgtatggt tcgtcggcgc cgggccgggc gatcgcgagc tgatcacgct
     6721 taaaggctac cgcctgctgc aacaggcgca ggtagttatc tatgccggtt cgctgatcaa
     6781 taccgaactg ctggattact gccccgcgca ggcagaacgc tacgacagcg ccgaactgca
     6841 tcttgagcag attatcgagc tgatggccgc gggcgtgaaa gcgggaaaaa cggtggtgcg
     6901 gttgcaaacg ggcgatgtct cgctgtacgg ctccgtgcgt gagcaaggcg aagagttaac
     6961 ccgccgtggt atcgactggc aggtagtgcc tggcgtcagc gcgtttctcg gcgctgcggc
     7021 ggagctgggt gtggaatata ccgtaccgga ggtatcgcag agtctcatta ttacccgtct
     7081 ggaagggcgt acgccagtac cggcgcgcga acaactggag gcgttcgcca gtcaccagac
     7141 gtcgatggcg atttatctct ccgttcagcg tattcatcgg gtggcggaac gtctcattgc
     7201 cggcggttat ccggcaacta cgcctgtcgc agtcatctat aaggctacct ggccggaaag
     7261 ccagaccgtt cgcggcacgt tagcggatat tagcgacaaa gtacgtgatg ctggcatccg
     7321 taagacggcg ctaatcctgg tcgggaattt tctgggtaag gagtatcact actcaagact
     7381 ttatgcagcg gactttagcc atgaataccg taaagcctga atccattgcg ttgttttgcc
     7441 tgacgcccgg cggcgtggcg ctggcaaaga gactcgccgc gatgctgccg ttaacctgct
     7501 ttaccagtga aaaactgcgg gaagagggat ttattccctt cgatggcgga ttcgctaata
     7561 ccgcccggca ggcttttacc acttataccg cgcttatttt tatcggcgcg accggcattg
     7621 ccgttcgtgt cctggcgccg ttagtgaacg acaagttcag cgatccggcg gtggtcgtca
     7681 ttgatgaacg tggtcagcat gtcattagcc tgctttccgg tcatgcgggc ggggccaatg
     7741 ccttgacgcg ctacctggca ggaatgttag gcgccgatcc ggtgattacc acggcaacgg
     7801 atgtcaatga gatgtccgcg ttggacacct tagctttcca gcttaacgcc cgcatgtccg
     7861 atcttcgaac ggcggtaaaa accgttaacc agatgttggt cagtcatcaa cgtgtggggt
     7921 tatggtggga tgccgaacta acggaagaga tcggccagtg tgatattcgc ggttttatcc
     7981 ctgttgatga tttgcagcgg ttgcctgaac tggatgcgct tatctgcgtc tctttgcgta
     8041 atgacctccc tgagcttccc gtactgcact ggaaactggt gccccagcgc gtggtggcgg
     8101 gaattggctg tcgccgcgat acgccatttc ccctgttagc gacattactg gcgcgtcagc
     8161 ttgaagcgca gaaactcgat ccgctggcgt taaaagcgat tggcagcgtc acgctcaaaa
     8221 aaggggagcc ggggcttatt cagctcgcct cctgctgccg cgtgcctttt aaaaccttta
     8281 ccgccgaagc gttgcgcgaa ttcgaacacc attttcccgg ttctggcttc gtcagaaaaa
     8341 cggtgggcgt tggcagcgta tccggcccgg ctgcgtggtt attaagccag ggtcaattgt
     8401 taggcgaaac cctgcgcgaa cagggcgtca ctattacttt gggagtttca cactgatgtt
     8461 aagcgtaatc ggaattggcc ctggctcaca ggcaatgatg acgatggagg cgattgaggc
     8521 gcttcaggcg gcggaaatcg tcgtgggcta caaaacctat acccatctgg ttaaagcatt
     8581 caccggcgac aaacaggtga tcaagaccgg catgtgtaag gaaattgaac gctgccaggc
     8641 ggctattgaa ctggcgcagg ccgggcataa cgtagcgctg attagcagcg gcgacgccgg
     8701 tatttacggc atggcgggac tggtgctgga gctggtgagc aagcagaaac tggacgtcga
     8761 ggtgcggctc attcctggca tgaccgccag catcgccgcc gcctctttac tgggcgcgcc
     8821 gctaatgcat gacttctgcc atatcagcct cagcgacctg ctgaccccgt ggccggttat
     8881 tgaaaaacgc atcgttgccg ccggagaggc agactttgtt atctgttttt acaacccgcg
     8941 cagccgcggg cgcgaagggc atctggcgcg cgcgtttgac ctgcttgccg ccagtaaaag
     9001 cgcgcaaacg ccggttggcg tggtgaaatc cgccggacgt aagaaagagg aaaaatggct
     9061 gaccacgctc ggcgatatgg attttgaacc ggtagatatg accagtctgg tcatcgttgg
     9121 taataaaacg acctatgttc aggatgggct gatgataacg ccgcgaggtt acacgctgtg
     9181 aatgaggggg aggtgctggt ggtgggcggc accagcgatg cgcgcgcgtt atgccgacaa
     9241 ctgggtgcgg cgaacgtcgc gtacacctta tctgtggcga cgccagccgg aaaagcgctg
     9301 gctggcgaca ttaaaggaca ggtgcgctgt ggtcgtctgg agtacgggca gatggtcgca
     9361 tggctaaaag aaaaccgtac tcgctgggta atagatgcgt cgcatcctta tgcagaaatg
     9421 gtcagccata acctccttcg cgcctgtgaa acggcggacg tgttgttaag tcgttatcag
     9481 cgtccggagc agcttagcaa tctgacgcat ccgcttctct atacggcgcg cagtattgcc
     9541 gatgcctgcg agatagcgag gcgttttggt ccgcgcgtgt tactgacgac cggcagtaaa
     9601 gatctggccg tctggcgtgc cgggctggcg gaaaaaacgt tgctggcgcg cgtactgccc
     9661 gtggcggagg tgattcaacg ctgcagcgaa ctggggttcg gcgttggaga aattttcgca
     9721 ctgtgtgggc cgttcagcgc tgattttaac gccgcgtttt accgccagtg ccgggctgac
     9781 gtggtcatta ccaaagcgtc cggcgcggag ggggatatca ggaaaaagtt cagccctgtc
     9841 tggatgcggg cattccctgc atcgttattg cgcgcccgac gccgctcgtg acgggtgatg
     9901 agttactgga aagctaggcc gcctttgcgc agcgtttatc gcgctggctg gccgcagcta
     9961 aggagtaaaa atgaaaaaag cgcttctggt ggtcagtttt ggcaccagct atcacgacac
    10021 ctgtgaaaaa acattgtggc gtgcgaacgt gatctggcgg agtcctgtcc cgatcgcgac
    10081 ctgtttcgcg ccttcacttc cggaatgatc attcgcaagc ttcgccagcg tgacggtatc
    10141 gacatcgata cgccattaca ggctttgcaa aagcttgcag cacagggata tcaggacgtg
    10201 gcgattcagt cgttgcacat tattaacggc gacgaatatg aaaaaattgt ccgtgaagta
    10261 caaatcttgc gtccgttatt tactcgcctg acgctgggcg tgccgctgct gagcagccat
    10321 aacgattatg tgcagctaat gcaggcgttg cgacaacaga tgccatcgct cagacaaacg
    10381 gagaaagtcg tttttatggg ccacggcgcc agccatcatg cattcgcagc ttatgcctgc
    10441 ctcgatcata tgatgaccgc gcagcgcttc ccggcgcgcg tcggcgctgt agaaagctac
    10501 ccggaggtcg acatcctgat cgacagcctg cgtgacgaag gcgtcaccgg catacatttg
    10561 atgccattaa tgctggtggc gggcgatcac gccataaatg atatggcttc agacgacggc
    10621 gactcatgga aaatgcgctt taacgcggcg ggcattccgg cgacgccgtg gctgagcggg
    10681 ctgggagaaa acccggctat ccgggcgatg tttgtcgcgc atttgcacca ggcgctgaac
    10741 atggcggtag aggaggcggc atgaacggta aattatacgc attaagtacc gggccaggcg
    10801 cgcccgacct gataaccgtc cgcgcagcgc ggattcttgg ctcgctggac attctgtatg
    10861 cgcccgccgg tcgtaagggg ggcgatagtc tggcgttgtc gattgtgcgc gactatctcg
    10921 gcgagcagac ggaagtacgt tgttgccatt tccctatgag cgctgacggc gccgagaaag
    10981 aagcggtctg gaacgaggtt gccgccgcgc ttaccgcaga ggtggaagcg ggtaaacagg
    11041 tcggttttat taccctgggc gatgcgatgc tattcagtac ctggattttt ttactccaga
    11101 gaatcggctg cccggagtgg ctggagattg tccccggcgt cacgtccttc gccgcgatag
    11161 ccgcccgcgc gaaaatgccg ctcgccatag aacggcaatc gctggcggtt atttcttgta
    11221 ccgcgccgga agcggaaata gcccaggcgc tacaacagca tgatagcctg gtgttgatga
    11281 aagtgtatgg ccgattcgcc cgtattaaag cgttgctggc gcaggctggc ctgctggaat
    11341 gcgccttaat gatgtccgag gccacgctgc ccggcgagca gtgctggcgc cacctccacg
    11401 aggtcaacga tgatcgagcg ttgccctatt tttcgaccat tctggtcaat aaacagtggg
    11461 agtatgcaga atgaaacttg aacagcagct tagacagttg tctttcagtg gactggctgc
    11521 agcgctattg ctgatggttg tcccgcaaca ggcgtttgcg atgcatatca tggagggctt
    11581 tttaccgcca gtgtgggcgc tggcctggtg gttactgttt ttaccctgct tgtggtatgg
    11641 gctggtacgc ttacggcgta ttgtgcagga ggataatcat cagaaggtac tgctggcgct
    11701 gtgcggcgcg tttatttttg tcctgtcccg ctcaaaattc cgtcggtaac ggggagttgt
    11761 tcacatccga ccggcgttgg tctggcggtt atcttgttcg ggcctggggt ggtggcgatt
    11821 ctcggcgcgg ttgtgctgtt gtttcaggcg ctattgctgg cgcacggcgg cctgacgacg
    11881 cttggcgcaa acggaatgtc gatggcggtg attggcccgg ttgtcggtta tctggtgtgg
    11941 aaaatggcct gccgtgccgg actgcgccgc gatgtcgccg tttttctgtg cgcgatgctg
    12001 gcggatttgg caacctattt tgtgacttca gtccagcttg gcgttgcgtt tcccgatccc
    12061 catgccggag cgacagggtc tgttgtgaag tttatgggga ttttctgcct cacacagatt
    12121 cctgtcgcta ttgctgaagg tttattaacc gtcatgattt atgaccagtt aaccaaacgg
    12181 caagtgatta ccgtacaagg acattaaaat gaaaaaaacg ttgatgttgt tagcgatggt
    12241 ggtggcgctg gtgattctgc cgttttttat taaccatggc ggtgaatatg gcggttcaga
    12301 cggcgaagcg gaaagccaga ttcaggctct tgcgccgcag tataaacctt ggtttcagcc
    12361 gttatatgaa cccgccagcg gtgaaattga aagcctgctg tttacccttc agggctctct
    12421 tggcgcggcg gtgatttttt atatcctggg gtattgcaaa ggtaaacaac gccgtgatga
    12481 ccgggcttga tcgactcagc tatcaaagcc gctgggcaca cgttgcgccg cagcgcaagt
    12541 ttttgctgtg gctggcgatg atgatactgg cgtttgttct gccgcctgta gggcagggca
    12601 ttgagctgct gatcattgcc ggattgagct gttggctatt gcgcatatcc ctctggcgtt
    12661 ggtgtcgatg gatggcgata ccttttggat ttttgttggt cggcgtgata acgattatct
    12721 tcagcatcag ccgcgagccg caaatgctgc tggctggcat atctgttggg ccgtactgga
    12781 tcgggattac ccgtgcgggc gtggttacgg cgaatgaaac gttctggcgt agcctgacgg
    12841 cgctgtccgc gacgttgtgg ctggtgatga acctaccgtt tccgcagtta attagcttgc
    12901 ttaagcgcgc gcatattcca cgcctgctta ccgagcaaat cctgttaacg tggcgctttc
    12961 tctttattct tctggatgag gcggtggcaa tccgtcgtgc gcaaacgctg cgttttggtt
    13021 attgcagcct gccgaacggc tatcgatctc tggcaatgct gactggactc ctgtttacgc
    13081 gggtgttaat gcgttatcag caaatgacca ccacgctgga tatcaaactg tatcagggtg
    13141 attttcacct gtaaggacta ttatgcttgc cacttcagac ctgtggtttc gttatcagga
    13201 tgagccggta cttaaagggt taaatctgga tttttcgctc tcgcctgtta ccggtttggt
    13261 gggcgcgaac ggttgtggga agtctacgct ttttatgaac ctgagcggcc tgttgcgtcc
    13321 gcaaaaaggg gccgtattgt ggcagggaaa accgttggat tacagcaagc gcggactact
    13381 ggcgctgcgc cagcaagttg cgacggtttt tcaggaccct gaacagcaga ttttttatac
    13441 tgatatcgat agcgacattg cgtttagttt acgtaatttg ggtgtgccgg aggcggaaat
    13501 cacgcgccgc gtcgacgagg cgctaacgct ggttgacgcc caacattttc gccatcagcc
    13561 cattcagtgt ttgagtcatg gacaaaaaaa acgtgtggct atcgccggag cgctggtgct
    13621 acaggcgcgc tatctattgc tggatgaacc cactgctggt cttgatcccg cagggcgcac
    13681 tcagatgatt gctatcatca ggcggattgt ggcgcaggga aatcatgtca ttatctccag
    13741 ccatgatatc gatcttattt atgaaattag cgatgccgta tacgtgttac gccagggcca
    13801 gatcctgatg catggcgcgc ctggcgaggt tttcgcgtgt acggaagcga tggaacacgc
    13861 ggggctaacc cagccctggc tggtcaaact tcatactcaa ctgggactgc cgctgtgtaa
    13921 aacagaaacg gagttttttc atcgaatgca aaagtgcgca ttcagggagg cgtcatgacg
    13981 caggcagtta tgttgcaggg gacggcatcc gacgtcggca aaagtgtgct ggtggccggt
    14041 ttatgccgca ttttttatca ggatggtctg cgtaccgcgc cgtttaaatc gcaaaatatg
    14101 gcgcttaatt ctggtattac gccggatggt aaagagatgg ggcgggcgca gatttttcag
    14161 gcggaagccg cggggatcac gccagatgtg cgtatgaatc cggtgctgct caaaccgacc
    14221 agcgatcgcc aggcgcaggt cgtgctgatg gggaaagtgg cgaccaatat ggatgcggtg
    14281 agttaccatg actataaacc gcgtttgcgt gagcaaatcc ttgcggtcta taacagcctg
    14341 gcgcaggaat atgacgttat tgtgctggaa ggcgccggaa gcccggcgga aatcaatctg
    14401 cgcgatcgcg atatcgtcaa tatgggaatg gcggaaatgg cccagtgtcc ggttattctg
    14461 gtggcggata tcgaccgggg cggcgtattc gccgctattt atggcacgct ggcgctactg
    14521 cacaaacagg agcgtgacag agtaaagggc gtcattatca acaaattccg cggcgacgtg
    14581 gcgctactct attccggtat cgaacaaatc gaatcgctta ccggcgtccc ggttctggga
    14641 gtgatgccat ggctggatgt ggatctggaa gatgaagatg gcgtcgcgct gcaaaacgat
    14701 aaatatcgcg gtaacgcccc ccgtgatatc actattgcca ttgtgcaact gccacatatt
    14761 tctaacttta cggattttaa cgctctggcg gcgcagccgg atgtgcgcat acgctatatt
    14821 cgccgcccgg aagcgttgac tgacgctgat ctggtgatcc tgccgggcag taagaatacg
    14881 ctgagcgacc tcgcctggct gcgcgaaagc gggatggcgg atgcggtatt gcagacacat
    14941 cggcagggcg tgccggtgat gggaatttgc ggtggctacc agatgctggg cgacactatt
    15001 gtggatgagg tggagtcggg gctgggtacg cagccgggcc tgggactgct taatacgatc
    15061 actcgctttg cacaggataa aaccacgacg caggttaacg cgacaatgtc aggcgagctg
    15121 cccggctggc tggctgccgc ggcggggcta ccggtacgcg gttatgaaat ccacatgggg
    15181 gaaacggtgc tgcaggaagg atgctgtacg gccatgacgt tacagaaaaa tggatgctct
    15241 gtggcggatg gcgcggtcac cgccgacgga ctggcgtttg gcacttacct tcacggtctg
    15301 tttgacagcg atgcctttac ccgtgcggtg gtcaatgggt tacgggcgcg aaaagggctt
    15361 gcgccgtggg aaacgacttt ttgttatgcg gagcataaag cgcggcaatt tgatctgctg
    15421 gcggaagcga tgcggcaaca tattgatatt gataaaattt acaccatcat gcaacagcat
    15481 caggagccgg tatgatgatt ctggtgacgg gcggggcgcg tagtggtaaa agccgtcatg
    15541 ctgaagcctt aattagcgat gcgccgcagg tactgtatat cgccacctcg cagattcttg
    15601 atgacgagat ggcggcgaga attcagcatc ataaagatgg caggccggca cactggcgga
    15661 ccgcagaatg ctggcggcat cttgatacgt tgattaccgc ggatcttgcc cctgacgacg
    15721 cgattttgct ggaatgtatt accaccatgg tgacgaatct gctgtttgcg ctgggaggcg
    15781 aaaacgatcc cgaacagtgg gattacgcgg cgatggagcg cgccattgac gatgaaattc
    15841 agattttaat tgcagcctgc cagcgctgcc cggcgaaagt ggtactggtg acaaatgaag
    15901 tgggaatggg gatcgtcccg gaaaaccgcc tggcgcgcca ttttcgtgat attgccggtc
    15961 gggtcaacca acgactggcg gcagcggcgg atgaggtctg gctggtggtc tcaggtattg
    16021 gagtcaaaat taaatgagta agctgttttg ggccatgctc gcttttatta gccgcttgcc
    16081 cgtgccgtca cgctggtcgc agggactgga tttcgagcag tattcgcgtg ggatcgtgat
    16141 gtttcccttt atcgggttga ttctgggggg gattagcggc ctgattttca tcctcctgca
    16201 accctggtgc ggtattccgc tcgcggcgtt gttctgtatt ttggcgctgg cgctgctgac
    16261 cggtggtttt cacctggatg ggctggccga tacctgcgat ggcatttttt ccgcgcgccg
    16321 ccgcgagcga atgctggaga ttatgcgcga tagtcgtctg ggaacccatg gcgggctggc
    16381 gcttattttt gtgctactgg caaaaattct ggtggtcagc gaactggcgt tacgtggaac
    16441 gccaatgttg gcggcgctgg cggcggcctg tgcggccgga cgcggcagcg ctgttttatt
    16501 gatgtaccgt catcgctacg cccgtgaaga ggggcttggc aatgtattta tcggtaaagt
    16561 cagcggacgg caaacctgca ttactctggg attggcggta atcgtcgcca cggtattact
    16621 gcttggtatg caaggcctgg ccacaatggt ggtcacactc gcggcgattt tcatccttgg
    16681 ccagttgctt aaacgtacgc ttggcggtca aaccggcgat acgctgggcg cggcgatcga
    16741 acttggcgaa ctgatctttc tgctggctct gttatgagcc gattattacg gacgagacat
    16801 cttatgcaga cactacacgc tttattccgt gacattcctg cgccggacgc cgaggcgatg
    16861 gcgcgtgcgc agcaacatat tgacggcctg ctcaaaccgc cgggtagctt gggcagactg
    16921 gaaaccttag ccgttcagct cgcgggaatg ccgggtctta acggtacgcc gcaggtaggt
    16981 gaaaaggcgg tgctggtgat gtgcgccgac catggcgtct gggatgaagg cgtagcggtt
    17041 tcgcccaaaa tcgtgacggc gattcaggcg gcgaatatga cgcagggaac aaccggcgta
    17101 tgtgtgcttg ccgctcaggc tggtgcaaag gtgcatgtca ttgatgtcgg tattgatgcc
    17161 gaacctattc cgggcgtagt tgatatgcgc gtcgcgcgcg gctgcggaaa tattgccgtt
    17221 ggcccggcga tgagtcgctc tcaggctgag gcgcttttgc tggaggtttc ccgctatacc
    17281 tgcgacctgg cgaaacgcgg cgtgacctta tttggcgttg gggagctggg aatggcgaac
    17341 actacgccag ccgccgcgat ggtcagcgtt tttacaggaa gtgatgcaaa agaggtggtg
    17401 gggattggcg cgaatcttcc gccttcccgc atcgataata aagtagacgt cgtgcggcgg
    17461 gcgattgcga ttaatcagcc caatccgcgc gacggcattg atgtgttgtc gaaggtgggg
    17521 gggtttgatc tggtcgggat gaccggcgtg atgcttggcg cggcaaggtg tggcttaccc
    17581 gtattgctgg atggctttct ttcctactcg gcagcgctgg cggcctgtca gattgcgcct
    17641 gcggtgagac cttatctgat cccgtcgcac ttttcggcgg aaaagggcgc ccgcatcgcg
    17701 ctcgcgcatt tgtctatgga accctatttg catatggcga tgcggttagg tgaaggaagc
    17761 ggcgcggcgc tggcgatgcc gatcgtggaa gccgcgtgcg ccatgttcca caatatgggg
    17821 gaattggcgg ccagtaatat tgtcctgccg gaggggaacg caaacgcaac ataacccggg
    17881 cgcacaacac cagccatgtg agaaaaaagc tatacttaac gcacacctgc cgcgacaaag
    17941 gaagggatat aatgcgtcgt atcacacctt tttttccgtt tttcgtcttg ttggtaagcc
    18001 atttctcgct ggctataagc tatccgttgc cgcccgaagg cagtcgtctg gtaggacagc
    18061 ctgtcacaat cgccgtacct cagaacaata ctcagccctt agagtcattt gccgcccgct
    18121 atggtcaggg gttgagtaat atgcttgaag cgaatcccgg cgtggatgtg tttttacctc
    18181 agtctggttc cacactggta gtgccgcagc agttgattct gcctgacacc gttcgtgaag
    18241 gtattgtggt aaacgtcgcc gagatgcgcc tttattatta tcccgcaggc acgaatacgg
    18301 ttgaggtact acccattggt attggtcagg ctggccgtga aacgccgcgc aactgggtaa
    18361 ctgcggttga acgcaaacaa gatggcccgg tttgggtgcc aacggctaat acgcgtcggg
    18421 aatatgctaa agagggaaaa acgctgcccg cgatggtgcc tgcggggccg gataacccta
    18481 tggggctata cgcaatatat atcggcaggt tatatgccac ccatggcact aacgctaact
    18541 ttggcattgg ccttcgcgtc agtcagggct gtatccgttt acgcaatgac gatattaaat
    18601 atttattcga ccatgttcct gtaggaaccc gcgttcagat tatcgacagg cccgttaaat
    18661 tttcggtaga gccggatggc agtcgttggc tggaggtaca cgaaccgctt tctcgcaacc
    18721 gtgctgaatt tgagtcagac aaaaaagttc cattgcccgt tacgccagtg ctgcgcacgt
    18781 ttatcaaagg ggatgacgtt gatacttcgc gggttaatga ggtgctggag cgccgttccg
    18841 gaatgccggt caacattagc gcaggcaggt ctggccttta aatatcctgc cacattgctg
    18901 gttttcatgg gctggaacat ctgtattagt agtgagtgtc atggcagggg cttcattttc
    18961 tcaacgaacc gcgaggccgc cgattaagcc cccaaaaact atggatgcca aaaagcccgg
    19021 aaaaccttat caggtcaacc gggtaaagat aagttcttat tttttaaacg tctccggact
    19081 cgcagggata tcccgaaact aaaatctggc tcctctgact ggactcgaac cagtgacata
    19141 cggattaaca gtccgccgtt ctaccgactg aactacagag gaatcgtgtg gggtcgtata
    19201 ttagcggcgg aaaaattttt gtcaaacccc atttaacccc ttacagattc gattgcgggt
    19261 tatctcatca ctttgttgca tttgcagaca ttttttctgc aaaaagcttt gcagccttac
    19321 gatttctcgc tcattattga aatgtggttt caactctctt ctttaaggtc cattttgaac
    19381 gtctccactg ccttacgcca ggttgtcgtc cgtacgccct ggtatgccaa acgcaagagc
    19441 tacaaagtgt tgttctggcg tgaaatcacc ccacttgcta tccccatttt tctggaaaat
    19501 acctgtgttt tgctaatggg cgtgctcagt acttttctcg tcagttggtt gggcaaggaa
    19561 gcaatggcgg gcgtggggct tgccgacagt tttaatatgg taattatggc tttttttgcg
    19621 gctatcgatc ttggtactac ggtggtggtc gcctttagcc tcggcaagcg cgataggcga
    19681 cgggcaaggg cggcggcgcg ccagtcgctg gtgattatga cgctatttgc cgttgtgctg
    19741 gcagtggtca ttcattattt cggcagtgaa attattaata ttgtcgcagg cgaggcgacg
    19801 ccagaagtaa aggggctggc gttaacgtac cttgaactga cggtactgag ttatccggct
    19861 gcggcaattg cgctaatcgg tagcggcgcg ctgcgtgggg cagggaatac gaaaatcccg
    19921 ttgatgatta acggcgggat gaacattctc aatattgtca tcagcagcat cctgatttac
    19981 ggggctttct cctggcaagg gctgggtttt gccggtgcgg ggctgggatt aaccatttcg
    20041 cgctacatcg gcgcggtagc gattatttgg gtgctgatga ttggttttaa tccggcgctg
    20101 cgcattccgc tgaaaagcta tctgaagccg ttgaatttcg gcattatctg ggaagtgatg
    20161 ggtatcggta ttccggcgag cattgaatca gtgctgttca acggtggcaa gctactgacg
    20221 caaatgtttg tcgccggaat gggcactaac gttattgcgg gtaactttat tgccttttcc
    20281 gtggcggcgc ttatcaatct gccgggtaac gcccttggtt cggcgtcgac tattatcacc
    20341 ggtaagcgtc ttggtaccgg gcaaattggt caggcagagc gtcaattgcg ccatgtattc
    20401 tggatgtcga ctatcgtact tacggcaatc gcctggggaa cagcgccgtt cgcgggtctg
    20461 tttgcctcat tttataccca ggagcaggac gtaaaagagg tagtgaaagt tctgctctgg
    20521 cttaatgctg cctttatgcc aatttgggct gccgcgtggg tgctgccgtc gggttttaaa
    20581 ggcgcgcgcg atgtgcgatt tgcgatgtgg gtatcgatgc tggggatgtg gggctgtcgc
    20641 gttgtggcag ggtatacgct tggtattgtg ctgggtatgg gggttgtagg ggtttggctg
    20701 gggatgtttc ttgactgggc cgtgcgtggc gcactgtttt actggcgtct gataagcggg
    20761 cgctggctgt ggagataccc gcgcgtaaag agggagtaag agctttttgc tgtgaaaatc
    20821 atcaggaaac ggtgaatttt aaccgaagtg tggaataaag cagcaaacga actttttttg
    20881 tgaaaacagg ctttgacaag ccaggggcac ctcgttaata ttcgccccgt tcacacgatt
    20941 cctctgtagt tcagtcggta gaacggcgga ctgttaatcc gtatgtcact ggttcgagtc
    21001 cagtcagagg agccagattt tagtttcggg acatcctggc gagtccggag acgtttaaaa
    21061 aataagaact tatctttacc cggttggcct gagaaggtct gccgggtttt ttgacatcca
    21121 tagtttttgg gggcttaatc gggggcctcg cggttcgctg agaaaatgga gcccccacct
    21181 atggcattaa ccgataccgc tatccgcaag attaaacccg tatcagtatg ctgacatata
    21241 gaggtgttcg attcaaacgg agcgatcaca caagcttgcc aggtgatgcc cctggtggga
    21301 atcgcgactg tctctttcat ctgatttcag atatttcccg tgatcttgat ccgttctttc
    21361 ccaaaagatt gatttctttc attcgaaaca aggatgtaca ataagtaaac caaaatagta
    21421 actatagagt ttctaatgga tacagtagaa gaactaaatg gaacatactt ctatgcagga
    21481 aaatccaatc tgactgctgc cgaacttctg ttatgatttt ctgtgagaat accgcaagcc
    21541 agtttgggat tggtgttgca gatttcgggg ctgttgttgc tctggtatca ggtcgtaata
    21601 atctttggac aagggcgaaa cccgctggag cgactaaagg cacatcatac gcgtccagga
    21661 ctgcacgtgc agtgtttaaa aagtcaaaat ttccctttgg aatatccctt ccgacatggt
    21721 taggcggtta caccccgtgg acagccagac gtgttatggt tcgtaacatt gcgccgtttg
    21781 ttggacgttc cattcctttg atcggggaaa ttatccttgc cgcagatgtg tcacaaatag
    21841 catatcgcac tatacgcgac tacaatacca ttgctcgggg caatgataag ttatgctaga
    21901 caatattgaa cagcaagttt acgagcttgt acggccttat gctggcacat atctgttcaa
    21961 cattaagcaa gtggaattaa caccagagat tgaccttgat actgatctga gcattgatga
    22021 acttgaagcc gaagatctca tgaataaatt cttcgagaaa ctcaatgtcg agcgaggtaa
    22081 cttcagaata gaaacctatt ttcctaatca ccctttttca tggcatccgt tcaagaaaac
    22141 ggagcctgta cccgtcccag atttcactat cagcatgctg atcgagtcag caaaagccgg
    22201 gaaatggtta tatgactaat tgtaatgaac ttaacaaatg gctgtaccag tacccttctt
    22261 tttgagcgat gatggtggcg ctaagatagt tctcttttct ttttaaaggg ttcatgttta
    22321 ctgccgccgc ccttacgcta acccctttag tttcctcctt tgctgtcata ctatcgaatg
    22381 acgtgcctca cctgtgaacg ctaaggagaa taatatggaa aataaaggca caaacctgac
    22441 acccgagcag gcgctggatc gcctggagga gctgtacgag cagtcggtta acgcgctccg
    22501 tgaagccatc gctgactatg ttgataacgg cacgctgccc gatccccatg ccaggcttaa
    22561 cggactgttt gtttatcctt cgctgtctgt aagctgggat ggcgcgacac cgaacccgcc
    22621 taaaacacgc gcttttggac gctttactca tcccggctgt tataccacta ccgttacgcg
    22681 gcctgcgcta tttcgcgctt atcttctgga acagcttaac ctcgtttacc atgattatgg
    22741 cgcgcatatt gcgatagagg cctcgcacca tgagatcccg tatccttatg tgatcgatgg
    22801 ctcggctctg acgctggatc gttctatgag cgccgggcta acgcgccatt ttcctaccac
    22861 agaactggcg cagattggcg atgagacggc agacggtctg ttccaccccg gcgaattcta
    22921 tccgttatcg cacttcgacg cgcgtcgtgt tgacttctcg ttggcccggt tacggcacta
    22981 taccggtacg ccggttgaac attttcagcc cttcgttttg tttaccaact acacccgcta
    23041 tgtcgatgag tttgtgcgct ggggatgcag ccaaattctt gatcctgaca gtccctatat
    23101 cgcgctttcc tgtgccggcg gaatttggat cacggcagaa acggaagcgc cggaagaggc
    23161 tatttccgat ctggcctgga agaagcatca gatgcctgcc tggcacctgg taacggcaga
    23221 tgggcagggg attacgctgg taaatatcgg tgtcggccct tcaaatgcta aaacgatttg
    23281 cgaccatttg gccgtgctgc ggcctgacgt ctggcttatg attgggcact gtggagggtt
    23341 acgagaaagt caggcgattg gtgattatgt gctggcccat gcctacttac gcgatgatca
    23401 tgtgctggat gctgttctgc cgcctgatat tccgattcca agcattgcgg aagtacagcg
    23461 tgcgctgtac gacgctacca aagcggttag cggaatgccc ggcgaagagg tgaaacagcg
    23521 actgcgcacg ggaacggtcg tcaccacgga tgaccgtaac tgggagcttc gttattccgc
    23581 atctgcgctg cgattcaacc ttagccgtgc ggtcgcgatt gatatggaga gcgcgacgat
    23641 tgcagcccag ggctatcgct tccgcgtgcc ttacggcacg ctgctttgtg tttctgacaa
    23701 acctttacac ggtgaaatta aactgcccgg gcaggcaaac cggttttatg agggggctat
    23761 ttcagaacat ttgcaaattg gtattcgtgc tattgattta ctacgcgcag aaggtgatcg
    23821 tttgcactca cgtaaattac gcacgtttaa tgagccgccg tttcgctaac gaaatgggct
    23881 gtcgcctgct gttgggcagg agcggaagag gcatatttat gtgatatgga aagtggttga
    23941 atgaagcctt agcgggaggt gattctgcat cccgctaagg ccttattgtg ccgcggcttc
    24001 atcaccatcg ccggagatct gtcgccgata atcgcgtcta cgtcaggaaa cgcgccggaa
    24061 ggcgaaaaca ttgcgccgca cttcacgctc cttgagcgcc tggacccaca agcccggatt
    24121 aacaagcaga taccgaccgt gagaatcgat cagcttaaag ggattatcag aaggcttgat
    24181 actgaggatt ttcgcgttgg acagggatat agggtggtca cgccattatc gaactgaaat
    24241 ggccccaaat cagaccacca atttcaccgg atgcgcaggt aaaaccagat acgcatcggt
    24301 aaaggttttc acgctaactt attgaaacct aattaaatag ggacttataa gtacgcctga
    24361 aaacagaaat ttggctcctc tgactggact cgaacttcat ctacatctcc tgttattact
    24421 gcttttgtta aacttagcca tatttttacc aacatattta ccatcattat tgttttcttg
    24481 tggttaaaat g
//
LOCUS       DAJVBX010000048        24206 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.048, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000048 DAJVBX010000000
VERSION     DAJVBX010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 24206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24206
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.048"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            97..744
                     /gene="fucA"
                     /locus_tag="OPV72_001692"
     CDS             97..744
                     /gene="fucA"
                     /locus_tag="OPV72_001692"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HCR9914026.1"
                     /translation="MERNRLARQIIDTCLEMTRLGLNQGTAGNVSVRYQGGMLITPTG
                     IPYEKLTESHIVFIDADGQHEQGKLPSSEWRFHMAAYQTRPDANAVVHNHAVHCTAVS
                     ILNRPIPAIHYMIAAAGGNSIPCAPYATFGTRELSDHVAVALKNRKATLLQHHGLIAC
                     EENLDKALWLAHEVEVLAQLYLSTLAIVDPVPVLDDEAIAIVLEKFKTYGLRIEE"
     gene            761..1909
                     /gene="fucO"
                     /locus_tag="OPV72_001693"
     CDS             761..1909
                     /gene="fucO"
                     /locus_tag="OPV72_001693"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HCR9914027.1"
                     /translation="MANRMILNETAWFGRGAVDALTDEVTRRGYHKALIVTDKTLVQC
                     GVVDKVTSRMDAAGLAWEIYAGVIPNPTISVVQEGLKVFTQSGADYLIAIGGGSPQDT
                     CKAVGIISNNPEFADVRSLEGLSPTRKPSVPIMAIPTTAGTAAEVTINYVITDEEKRR
                     KFVCVDPHDIPQAAFIDADMMDGMPPALKAATGVDALTHAIEGYITRAAWALTDALHI
                     KAIEIIAGALRGAVAGEKEAGEAMALGQYVAGMGFSNVGLGLVHGMAHPLGAFYNTPH
                     GVANAILLPHVMRFNAGSTNEKFRDIARAMGVKVEGLSLEEARNAAVEAVFTLNRDVG
                     IPLHLRDVGVRKEDIPALAQAAFDDVCTGGNPREASLADIVELYHTAW"
     gene            complement(2001..2756)
                     /gene="xni"
                     /locus_tag="OPV72_001694"
     CDS             complement(2001..2756)
                     /gene="xni"
                     /locus_tag="OPV72_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417278.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flap endonuclease Xni"
                     /protein_id="HCR9914028.1"
                     /translation="MAAHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIIHSQPTH
                     AVAVFDDDARSSGWRHQRLPDYKAGRPPMPDDLHNEMPALRAAFEQRGVRCWASDGNE
                     ADDLAATLALKVTEAGHQATIVSTDKGYCQLLSPGLRIRDYFQKRWLDAPFIEKEFGV
                     LPRQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVQFQNLEGIYAHLDEVPEKWRKKL
                     ETHKEMAFLCRDIARLQTDLHIDGNLQQLRLVR"
     gene            complement(2927..4294)
                     /gene="sdaB"
                     /locus_tag="OPV72_001695"
     CDS             complement(2927..4294)
                     /gene="sdaB"
                     /locus_tag="OPV72_001695"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461891.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase II"
                     /protein_id="HCR9914029.1"
                     /translation="MISVFDIFKIGIGPSSSHTVGPMKAGKQFTDDLIARHILTDVTR
                     VVVDVYGSLSLTGKGHHTDIAIIMGLAGNLPDTVDIDAIPSFIQDVNTHGRLLLANGQ
                     HEVEFPVDKCMNFHADNLSLHENGMRITALAGNKVLYSQTYYSIGGGFIVDEEHFGLT
                     NSEPVNVPYPYKTAADLQRHCQETGLSLSGLMMQNELALHSKEALEQHFAKVWEVMRS
                     GIERGITTEGVLPGKLRVPRRAAALRRMLVSQDKTTTDPMAVVDWINMFALAVNEENA
                     AGGRVVTAPTNGACGIVPAVLAYYDKFIREVNANSLARYMLVASAIGSLYKMNASISG
                     AEVGCQGEVGVACSMAAAGLAELLGGSPAQVCIAAEIAMEHNLGLTCDPVAGQVQVPC
                     IERNAIASVKAVNAARMALRRTSEPRVCLDKVIETMYETGKDMNAKYRETSRGGLAMK
                     IVTCD"
     gene            complement(4353..5642)
                     /gene="sdaC"
                     /locus_tag="OPV72_001696"
     CDS             complement(4353..5642)
                     /gene="sdaC"
                     /locus_tag="OPV72_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAAAP family serine/threonine permease SdaC"
                     /protein_id="HCR9914030.1"
                     /translation="MKTTQTSTIASIDSRSAWRKTDTMWMLGLYGTAIGAGVLFLPIN
                     AGVGGMIPLIIMAILAFPMTFFAHRGLTRFVLSGKNPGEDITEVVEEHFGIGAGKLIT
                     LLYFFAIYPILLVYSVAITNTVESFLTHQLAINPPPRAILSLILIVGMMTIVRFGEQM
                     IVKAMSILVFPFVAALMLLALYLIPQWNGAALETLSFDSAASTGNGLWMTLWLAIPVM
                     VFSFNHSPIISSFAVAKREEYGEGAEKKCSKILAFAHIMMVLTVMFFVFSCVLSLTPA
                     DLAAAKEQNISILSYLANHFNAPIIAWMAPIIAMIAITKSFLGHYLGAREGFNGMVIK
                     SLRGKGKSIEINKLNKITALFMLVTTWIVATLNPSILGMIETLGGPIIAMILFLMPMY
                     AIQKVPAMRKYSGHISNVFVVIMGLIAISAIFYSLFS"
     gene            complement(6207..7571)
                     /gene="ppnN"
                     /locus_tag="OPV72_001697"
                     /gene_synonym="ygdH"
     CDS             complement(6207..7571)
                     /gene="ppnN"
                     /locus_tag="OPV72_001697"
                     /gene_synonym="ygdH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide 5'-monophosphate nucleosidase"
                     /protein_id="HCR9914031.1"
                     /translation="MITHISPLGSMDMLSQLEVDMLKRTASSDLYQLFRNCSLAVLNS
                     GSLTDNSKELLSCFENFDINVLRRERGVKLELINPPEDAFVDGRIIRALQANLFAVLR
                     DILFVNGQIHNAGRFQHLDLESSTHITNLVFSILRNARALHVGEAPNMVVCWGGHSIN
                     ENEYLYARRVGTQLGLRELNICTGCGPGAMEAPMKGAAVGHAQQRYKDSRFIGMTEPS
                     IIAAEPPNPLVNELIIMPDIEKRLEAFVRIAHGIIIFPGGVGTAEELLYLLGILMNPA
                     NKNQVLPLILTGPKESADYFRVLDEFITHTLGEAARRHYRIIIDDAAEVARLMKKAMP
                     QVKENRRDTGDAYSFNWSMRIAPDLQVPFEPSHENMANLKLYPDQPVEILAADLRRAF
                     SGIVAGNVKEVGIRAIEANGPYKIHGDREMMRRMDDLLQGFVAQHRMKLPGSAYIPCY
                     EICA"
     gene            complement(7685..8533)
                     /gene="queF"
                     /locus_tag="OPV72_001698"
     CDS             complement(7685..8533)
                     /gene="queF"
                     /locus_tag="OPV72_001698"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HCR9914032.1"
                     /translation="MSSYENHQALDGLTLGKSTDYRDNYDASLLQGVPRSLNRDPLGL
                     TADNLPFHGADIWTLYELSWLNSQGLPQVAVGHVELDYTSVNLIESKSFKLYLNSFNQ
                     TRFDTWETVRQTLERDLRACAQGNVSVRLHRLDELEGQPVAHFHGTCIDDQDISIDNY
                     QFTTDYLQHAVSGEKQVEETLVSHLLKSNCLITHQPDWGSIQIQYRGRKIDREKLLRY
                     LVSFRHHNEFHEQCVERIFNDILRFCQPETLSVYARYTRRGGLDINPWRSNTDFVPAT
                     GRLARQ"
     gene            8602..9147
                     /gene="syd"
                     /locus_tag="OPV72_001699"
     CDS             8602..9147
                     /gene="syd"
                     /locus_tag="OPV72_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SecY-interacting protein"
                     /protein_id="HCR9914033.1"
                     /translation="MDELTAQALKAFTTRYCDAWQEKHGSWPLSEELYGVPSPCIISS
                     TRDAVYWQPQPFEGEENVNAVERAFDIMVQPALHAFYTTQFAGDMPAQFADEKLTLLQ
                     TWSQDDFRRVQENLIGHLVTQKRLKLPPTLFIATQENELEVISVCNLSGEVIKETLGT
                     RNRTVLAATLAEFLTQLNPLL"
     gene            9757..10086
                     /locus_tag="OPV72_001700"
     CDS             9757..10086
                     /locus_tag="OPV72_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqcC family protein"
                     /protein_id="HCR9914034.1"
                     /translation="MTTHDRVRQQLHALETLLREHRHWRLDAPQAHLFTSTQPFFMDT
                     MEPLEWLQWVLIPRMHTLLDNAQPLPEAFAVAPYYEMALAADHPQREAILAVLQDLDA
                     LFVRDKS"
     gene            10086..10868
                     /gene="truC"
                     /locus_tag="OPV72_001701"
     CDS             10086..10868
                     /gene="truC"
                     /locus_tag="OPV72_001701"
                     /EC_number="5.4.99.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(65) synthase TruC"
                     /protein_id="HCR9914035.1"
                     /translation="MLEILYQDPWLVAVNKPAGWLVHRSWLDRDEKVVVMQTVRDQIG
                     QHVFTAHRLDRPTSGVLLMGLSSEAGRRLAQQFEQHHIRKRYHAIVRGWLIDDAVLDY
                     PLVEERDKIADKFAREDKAPQPAVTQYRGLATVEMAVPTGRYPTTRYGLVELEPKTGR
                     KHQLRRHLAHLRHPIIGDSKHGDLRQNRSAAEHFACRRLMLHASRLELTHPFTGQPLI
                     IQAGLDETWMQVLTQFGWRGLLPDNERVEFTAASRQDETHLT"
     gene            10887..11336
                     /locus_tag="OPV72_001702"
     CDS             10887..11336
                     /locus_tag="OPV72_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HCR9914036.1"
                     /translation="MAEIGIFVGTMYGNSLLVAEEAEAILARQGHSATVFEDPELSDW
                     QQYQDKVALVVTSTTGQGDLPDSIAPLFHGIKDTLGFQPNLRYGVIALGDSSYPNFCN
                     GGKQFDALLQEQSAQRVGEILFIDASEHPEPESQSNPWVENWGTLLS"
     gene            complement(11486..11734)
                     /locus_tag="OPV72_001703"
     CDS             complement(11486..11734)
                     /locus_tag="OPV72_001703"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914037.1"
                     /translation="MQLLLGRLLCTLHAFIHWQEKYKKRATHTHRATTQYFGDELRLF
                     MAKAQDSGSHFTEMKSEGVGVDAGGVKREECETGRLIT"
     gene            11817..13175
                     /gene="gudP"
                     /locus_tag="OPV72_001704"
     CDS             11817..13175
                     /gene="gudP"
                     /locus_tag="OPV72_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactarate/glucarate/glycerate transporter
                     GudP"
                     /protein_id="HCR9914038.1"
                     /translation="MSSLSHAASSAEKRTNARYWIVVMLFIVTSFNYGDRATLSIAGS
                     EMAKDIGLDPVGMGYVFSAFSWAYVIGQIPGGWLLDRFGSKRVYFWSIFIWSVFTLLQ
                     GFVDIFSGFGIIVALFTLRFLVGLAESPSFPGNSRIVAAWFPAQERGTAVAIFNSAQY
                     FATVIFAPIMGWLTHEVGWSHVFFFMGGLGIIISFIWLKVIHEPNNHPGVNKKELEYI
                     AEGGALINMDQKDTKAKVPFSVKWGQIKQLLGSRMMIGVYIGQYCINALTYFFITWFP
                     VYLVQARGMSILKAGFVASVPAVCGFIGGVLGGIISDWLMRRTGFLNIARKTPIVLGM
                     LLSMVMVFCNYVNVEWMIIGFMVLAFFGKGIGALGWAVMADTAPKEISGLSGGLFNMF
                     GNISGIVTPIAIGYIVGTTGSFNGALIYVGVHALVAIISYLVLVGDIKRIELKPVAGQ
                     LS"
     gene            13172..14512
                     /locus_tag="OPV72_001705"
     CDS             13172..14512
                     /locus_tag="OPV72_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucarate dehydratase"
                     /protein_id="HCR9914039.1"
                     /translation="MTTQSSPVITDMKVIPVAGHDSMLLNIGGAHNAYFTRNIVVLTD
                     NAGHTGVGETPGGEVIYQTLVDAIPMVLGQEVARLNKVVQQVHKGNQAADFDTFGKGA
                     WTFELRVNAVAALEAALLDLQGQALNVPVCELLGPGKQRDAVTVLGYLFYIGDRTKTD
                     LPYLESTPGSHEWYRLRHQEALNSDAVVRLAEASQDRYGFKDFKLKGGVLPGEQEIDT
                     VRALKKRFPDARITVDPNGAWLLDEAIALCKGLNDVLTYAEDPCGAEQGFSGREVMAE
                     FRRATGLPVATNMIATNWREMGHAVMLNAVDIPLADPHFWTLTGAVRVAQLCDDWGLT
                     WGCHSNNHFDISLAMFTHVGAAAPGKPTAIDTHWIWQEGDCRLTKNPLEIKNGKIAVP
                     DAPGLGVELDWEQVRKAHDAYKKLPGGARNDAGPMQYLIPGWTFDRKRPVFGRH"
     gene            14533..15873
                     /gene="gudD"
                     /locus_tag="OPV72_001706"
     CDS             14533..15873
                     /gene="gudD"
                     /locus_tag="OPV72_001706"
                     /EC_number="4.2.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucarate dehydratase"
                     /protein_id="HCR9914040.1"
                     /translation="MSTQFTTPVVTEMQVIPVAGHDSMLMNLSGAHAPFFTRNIVIVK
                     DNSGHTGVGEIPGGEKIRKTLEDAIPLVVGKTLDEYKNVLTAVRNQFADRDAGGRGLQ
                     TFDLRTTIHVVTGIEAAMLDLLGQHLGVNVASLLGDGQQRSEVEMLGYLFFVGNRKVT
                     PLPYQSQPDEQCDWYRLRHEEAMTPETVVRLAEAAYEKYGFNDFKLKGGVLAGEEEAE
                     SIVALAKRFPQARVTLDPNGAWSLNEAISIGKYLKGSLAYAEDPCGAEQGFSGREVMA
                     EFRRATGLPTATNMIATDWRQMGHTLSLQSVDIPLADPHFWTMQGSVRVAQMCHEFGL
                     TWGSHSNNHFDISLAMFTHVAAAAPGKITAIDTHWIWQEGNQRLTKEPFEIKGGMVQV
                     PTKPGLGVELDMDQVMKAHELYQKHGLGARDDAMGMQYLIPGWTFDNKRPCMVR"
     gene            15951..17093
                     /locus_tag="OPV72_001707"
     CDS             15951..17093
                     /locus_tag="OPV72_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HCR9914041.1"
                     /translation="MKIVIAPDSYKESLSALEVATAIEQGFREIWPDADYLKLPLADG
                     GEGTVEAMVEATAGRIVHVEVTGPLGHRVNAFYGLSGDARSAFIEMAAASGLEQVPPA
                     QRDPLKTTSWGTGELIRHALDAGVEHIIIGIGGSATNDGGAGMVQALGARLRDAQGND
                     IAQGGIGLETLASIDISGLDKRLSACHIEVACDVTNPLTGKEGASAVFGPQKGATPEM
                     IERLDTALTRYAHLIARDLHVDVLDLAGGGAAGGMGAALYAFCGAQLRRGIEIVTDAL
                     HLEACLADADLVITGEGRIDSQTIHGKVPIGVANIAKRYNKPVIGIAGSLTADVGVVH
                     EHGLDAVFSVIYTICTLEDALKNASENVRMTARNVAATLKAGQQLR"
     gene            complement(17137..19893)
                     /gene="barA"
                     /locus_tag="OPV72_001708"
     CDS             complement(17137..19893)
                     /gene="barA"
                     /locus_tag="OPV72_001708"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase BarA"
                     /protein_id="HCR9914042.1"
                     /translation="MTNYSLRARMMILILAPTVLIGLLLSIFFVVHRYNDLQRQLEDA
                     GASIIEPLAVSSEYGMNLQNRESIGQLISVLHRRHSDIVRAISVYDDHNRLFVTSNFH
                     LDPSQMQLPAGAPFPRRLSVDRHGDIMILRTPIISESYSPDESAIADAKNTKNMLGYV
                     ALELDLKSVRLQQYKEIFISSVMMLFCIGIALIFGWRLMRDVTGPIRNMVNTVDRIRR
                     GQLDSRVEGFMLGELDMLKNGINSMAMSLAAYHEEMQHNIDQATSDLRETLEQMEIQN
                     VELDLAKKRAQEAARIKSEFLANMSHELRTPLNGVIGFTRLTLKTELNPTQRDHLNTI
                     ERSANNLLAIINDVLDFSKLEAGKLILESIPFPLRNTLDEVVTLLAHSSHDKGLELTL
                     NIKNDVPENVIGDPLRLQQVITNLVGNAIKFTESGNIDILVEKRALSNTKVQIEVQIR
                     DTGIGIPERDQSRLFQAFRQADASISRRHGGTGLGLVITQKLVNEMGGDISFHSQPNR
                     GSTFWFHINLDLNPNVIIDGPSTACLAGKRLAYIEPNATAAQCTLDLLSDTPVEVIYS
                     PTFSALPLAHYDIMILSVPVTFREPLTMQHERLAKAASMTDFLLLALPCHAQINAEKL
                     KQGGAAACLLKPLTSTRLLPALTEYCQLNHHPEPLLMDTSKITMTVMAVDDNPANLKL
                     IGALLEDKVQHVELCDSGHQAVDRAKQMQFDLILMDIQMPDMDGIRACELIHQLPHQQ
                     QTPVIAVTAHAMAGQKEKLLSAGMNDYLAKPIEEEKLHNLLLRYKPGANVAARLMAPE
                     PAEFIFNPNATLDWQLALRQAAGKPDLARDMLQMLIDFLPEVRNKIEEQLVGENPNGL
                     VDLVHKLHGSCGYSGVPRMKNLCQLIEQQLRSGVHEEELEPEFLELLDEMDNVAREAK
                     KILG"
     gene            19951..21246
                     /gene="rlmD"
                     /locus_tag="OPV72_001709"
     CDS             19951..21246
                     /gene="rlmD"
                     /locus_tag="OPV72_001709"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HCR9914043.1"
                     /translation="MAQFYSAKRRVTTRQIITVKVNDLDSFGQGVARHNGKALFIPGL
                     LPEESAEVIITEDKKQFARARVSRRLNDSPERETPRCPHFGVCGGCQQQHVGIDLQQR
                     SKSAALARLMKHEVNDIIAGASWGYRRRARLSLNCPPDKPLQMGFRKAGSSDIVNVEQ
                     CPVLAPQLEALLPRIRACLASLHGTRHLGHVELVQAGSGTLMILRHTAPLSAADKEKL
                     ERFSHSEGLSLFLAPFSEILETVSGEAPWYDSHGLRLTFSPRDFIQVNEAVNQQMVAR
                     ALEWLDVRAEDRVLDLFCGMGNFTLPLATRAASVVGVEGVQALVEKGRENAIRNGLHN
                     VTFFHENLEEDVTKQPWAKNGFDKVLLDPARAGATGVMRHIIKLKPIRIVYVSCNPAT
                     LARDSEALVNAGYEVTRLAMLDMFPHTGHLESMVLFERM"
     gene            21298..23532
                     /gene="relA"
                     /locus_tag="OPV72_001710"
     CDS             21298..23532
                     /gene="relA"
                     /locus_tag="OPV72_001710"
                     /EC_number="2.7.6.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP diphosphokinase"
                     /protein_id="HCR9914044.1"
                     /translation="MVAVRSAHINKAGEFDPKKWIASLGISSQQSCERLAETWAYCLQ
                     QTQGHPDADLLLWRGVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKS
                     IVTLIHGVRDMAAIRQLNATHNDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHL
                     REVKEAPEDERVLAAKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPAEYKRIAKLL
                     HERRLDREHYIEEFVGHLRAEMKNEGVQAEVYGRPKHIYSIWRKMQKKHLAFDELFDV
                     RAVRIVAERLQDCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTV
                     EIQIRTKQMHEDAELGVAAHWKYKEGAASGGVRSGHEDRIAWLRKLIAWQEEMADSGE
                     MLDEVRSQVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVP
                     FTYQLQMGDQVEIITQKQPNPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAG
                     RQILDDELAHLGISLKEAEKHLLPRYNFNELEELLAAIGGGDIRLNQMVNFLQSQFNK
                     PSAEEQDAAALKQLQQKTYAPQNRRKDDGRVVVEGVGNLMHHIARCCQPIPGDEIVGF
                     ITQGRGISVHRADCEQLAELRSHAPERIVEAVWGESYSAGYSLVVRVQANDRSGLLRD
                     ITTILANEKVNVLGVASRSDIKQQIATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARR
                     LHGG"
     gene            23617..23973
                     /locus_tag="OPV72_001711"
     CDS             23617..23973
                     /locus_tag="OPV72_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461876.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system ParD family
                     antitoxin"
                     /protein_id="HCR9914045.1"
                     /translation="MFLTYISFQVYSYVRFILTVEAVMARTMTVDLGDELREFIESLI
                     ESGDYRTQSEVIRESLRLLREKQAESRLQALRELLAEGLNSGEPQAWEKDAFLRKVKT
                     GMIKPDENGKINAKGQ"
     gene            23939..24157
                     /locus_tag="OPV72_001712"
                     /pseudo
     CDS             23939..24157
                     /locus_tag="OPV72_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001532579.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
BASE COUNT         5660 a         6132 c         6852 g         5562 t
ORIGIN      
        1 gatagttgct aactattcga ttatttcaac aggacagcag cgtgatgcga aaggcggttt
       61 tgttgtctca ttttgaatca cagagagagg taaataatgg aacgaaatag actggctcgg
      121 cagattattg atacctgtct ggaaatgacg cggttagggt taaatcaggg gacggcaggt
      181 aacgtgagcg tacgttatca gggcggaatg ctgattacgc cgacggggat cccctacgag
      241 aagctgacag agtcgcacat tgtctttatt gatgcagacg gtcagcatga gcagggcaag
      301 ctgccttcca gcgagtggcg ttttcatatg gcggcatacc agacgcgccc tgacgccaat
      361 gccgtggtac ataaccacgc tgtccattgt acggcagtct cgatcctgaa tcgcccgatt
      421 ccggcgattc actacatgat tgccgccgcg ggggggaact ctattccctg cgcgccctac
      481 gccacttttg gcacccgcga actttctgac catgttgccg tggcgcttaa aaatcgtaaa
      541 gcgacgctgt tacagcatca cgggcttatc gcttgtgaag aaaatttaga caaagcgttg
      601 tggctggcgc atgaagtgga agtgctggcg cagctctatt taagtacgct ggccattgtc
      661 gatccggtac cggtactgga tgacgaggcg atcgctatcg tactggagaa atttaaaact
      721 tacggattac gtattgaaga gtgatgtcag gagacaggcg atggcgaaca gaatgattct
      781 gaatgaaacg gcatggtttg gccggggagc ggtggacgca ttaaccgatg aggtgacgcg
      841 ccgcggttat cataaggcgc tgattgttac cgataaaacg ctggtgcaat gcggtgtggt
      901 cgataaggtt acaagcagaa tggatgccgc agggctggcg tgggagatct atgcgggcgt
      961 gatccctaat cctacgattt ccgttgtcca ggaagggctt aaggtcttta cccaaagtgg
     1021 cgcggactat ctcatcgcca ttggcggcgg ttctccgcag gatacctgca aagcggtcgg
     1081 tattatcagt aacaatccgg aatttgccga tgtgcgcagt ctggaagggc tatcgccgac
     1141 ccgtaaaccc agcgtgccga ttatggcgat cccgacaacg gcgggaaccg cggcggaagt
     1201 cactatcaat tatgtgatta ccgatgaaga gaaacggcgc aaattcgttt gtgtcgatcc
     1261 gcatgatatt ccgcaggcgg catttatcga tgccgatatg atggacggta tgccgcccgc
     1321 gctgaaagcg gcaacgggcg tggatgcgct aacccatgct attgaaggct atattacccg
     1381 ggccgcatgg gcgctgacgg atgcattaca tatcaaagcc attgagatta ttgctggcgc
     1441 gctgcgcggc gccgtagccg gagaaaaaga ggccggtgag gcgatggcgc tggggcaata
     1501 cgttgccggg atggggtttt ccaatgtggg gctgggactg gtgcatggga tggcgcatcc
     1561 gttgggcgcg ttttacaaca cgccgcacgg cgtcgcgaat gctattttgc tcccgcatgt
     1621 gatgcgtttc aatgccgggt ctaccaacga gaaattccgt gatatcgccc gggcgatggg
     1681 ggtgaaggta gaaggattga gccttgaaga ggcgcgtaat gccgcagtgg aagccgtatt
     1741 tacgctaaat cgcgatgtgg gaattccgct gcatttgcgt gatgtcggcg ttcgaaaaga
     1801 ggatatcccg gcgctggcgc aggcggcgtt cgatgatgtc tgtacgggcg gcaatccgcg
     1861 tgaagcgagt ctggcggaca ttgtcgaact gtatcatacc gcctggtaat tttgccggat
     1921 ggcgctgcgc ttatccgctc tacatttcgt gcagttctgt aggccggata aggcgttcac
     1981 gccgccatcc ggcaacaaaa ctaccgtacc agccgtagct gctgtaagtt tccgtcgata
     2041 tgtaaatcgg tttgcagacg tgcaatatcg cggcaaagaa atgccatttc tttatgcgtc
     2101 tcaagctttt tgcgccactt ttccggcacc tcgtccagat gggcgtaaat tccctccaga
     2161 ttttgaaact gaaccaacag ctgggtcgcg cttttagggc cgataccggc aacgccgggg
     2221 actttcgaac tactgattcc tgccagaccc cagtaatccg gcaactgccg ggggagtacg
     2281 ccaaactctt tttcaataaa cggcgcgtcc agccagcgtt tctggaagta gtcgcgaatg
     2341 cgcaatcccg gagagagcaa ctggcaatag cctttatcgg ttgacacaat ggttgcctgg
     2401 tgtccggctt cggtaacttt tagcgccagc gtcgccgcca gatcgtccgc ttcgttaccg
     2461 tctgatgccc aacagcgtac gccgcgctgt tcaaacgcgg cgcgtagggc gggcatttca
     2521 ttatgtaaat cgtcaggcat cggcggacgt cctgctttgt agtccggcaa acgctgatga
     2581 cgccagccgc tgctgcgcgc gtcgtcatca aataccgcta cggcatgggt tggctggctg
     2641 tggataatca attgatcgag cgcgtgttgg caggtttcca cacagggcga tccctgaacg
     2701 gcgtgaatac ggcgaatcaa attgagcgcg tcgacgataa gcagatgagc agccacggtg
     2761 ttctccctta caaacctgcg cgtagggtaa cattcacggc ggggggaggc gagcattgcg
     2821 aaatcgcgct atccgtagac ctgataagcg aagcgccatc aggcaacaaa agccggatgg
     2881 cggcgagcgc cttatccggc ctacagatcc taaaatgtgc tgagaattaa tcgcaggtaa
     2941 cgatcttcat cgccaggccg ccgcgcgaag tttcgcggta cttagcgttc atgtctttac
     3001 cggtttcgta catggtctca atcactttat cgaggcatac gcgcggttcg ctggttcggc
     3061 gcagcgccat acgcgcggcg ttgaccgctt tgactgaagc aatcgcgtta cgctcaatgc
     3121 agggaacctg gacctgaccg gcaaccggat cgcaagttag ccccagatta tgctccatgg
     3181 cgatttctgc ggcgatacac acctgcgccg gactaccgcc cagcagctcg gccagacccg
     3241 ctgccgccat ggaacaggcc acgccgacct ctccctgaca acccacttcg gcgccggaaa
     3301 tagaggcgtt catcttatac agcgagccaa tcgcgctggc gaccagcata tagcgagcaa
     3361 gtgagttagc atttacttcg cggataaatt tgtcatagta cgccagcacc gccggcacaa
     3421 taccacatgc gccgttagtc ggggcagtga ctactcgtcc gcctgcggca ttctcttcgt
     3481 tcaccgccag cgcgaacata ttgatccagt cgacgaccgc catcggatcg gtggtggtct
     3541 tatcctgact gaccagcatc cgacgcagcg ccgccgcgcg acgcggaacg cgcagtttgc
     3601 ccggcaatac gccctcggtg gtgataccgc gctcaatacc gctgcgcatc acctcccaga
     3661 ccttggcgaa gtgctgctcc agcgcttctt tactgtgcag agccagttcg ttttgcatca
     3721 tcagaccgga gagcgacaga cccgtctcct ggcaatggcg ctgtaaatcc gcggcggttt
     3781 tataaggata cggtacgtta acgggttcgc tatttgtcaa accaaagtgc tcttcatcga
     3841 cgataaagcc gccgccaatg gagtagtagg tttggctgta gagcacttta ttgcccgcca
     3901 gcgcggtaat acgcatcccg ttctcatgca gagacaggtt gtcggcgtgg aaattcatgc
     3961 acttatcgac cggaaattcg acttcatgct gcccattggc cagtagtaaa cgcccatggg
     4021 tgttcacatc ctggataaag gacggaatgg cgtcgatatc gacggtgtcc ggcagattcc
     4081 ccgccaggcc cataataatg gcgatatcag tgtggtggcc tttacccgtc aatgacagag
     4141 agccgtagac atccaccacg acgcgggtga catctgtaag aatatggcgg gcaatcagat
     4201 cgtccgtgaa ctgcttgcct gctttcattg gtccgacggt gtgagaactg gaagggccaa
     4261 tgccgatttt aaaaatatcg aatacgctaa tcatagggca tccattgcgg ttgtatcata
     4321 gagaagcgcc gcggtaagcg gcgctaaagg acttagctga acagtgagta gaaaatagcg
     4381 gagatggcaa tcaggcccat aatcacaacg aatacgttgc tgatatgacc gctgtactta
     4441 cgcattgccg gtactttctg gatggcatac atcggcatca ggaacagaat catcgcgatg
     4501 atcgggccgc ccagggtttc aatcatgccc aggatgctgg ggttcagcgt cgccacaatc
     4561 caggtggtga ccagcatgaa cagcgcggta attttattca gtttgttgat ttcgatggat
     4621 ttacctttac cacgcagcga tttaatcacc atcccgttaa agccttcacg cgcgcccagg
     4681 tagtggccga ggaaggattt ggtgatagca atcatcgcaa tgatcggcgc catccaggcg
     4741 atgatcggcg cgttaaagtg gttcgccagg taagacagaa tagagatgtt ctgctctttt
     4801 gccgctgcca gatctgccgg cgtcaggctc agcacgcagc tgaagacgaa gaacatcacg
     4861 gtcagcacca tcatgatgtg ggcgaaggcc agaattttag aacatttctt ctcagcgcct
     4921 tcaccgtact cttcacgctt cgcaaccgcg aaggaggaga tgatcgggga gtggttgaaa
     4981 gagaaaacca tcaccggaat cgccagccac agcgtcatcc acagaccgtt accggtagac
     5041 gcggcggaat caaaggacag agtttccagc gccgcgccgt tccactgcgg gatcaggtac
     5101 aaggccagca gcatcagcgc agcgacgaac gggaatacca ggatactcat cgccttaacg
     5161 atcatttgct cgccgaagcg cacgatggtc atcatgccaa caatcaggat cagggaaaga
     5221 atcgcccgcg gcggcggatt aatcgctaac tggtgggtca ggaagctttc cacggtatta
     5281 gtaatcgcca cgctgtaaac cagcaggatg gggtaaatcg cgaagaagta gagcagggta
     5341 atcagtttac ctgcgccgat accgaagtgt tcctcaacga cttcagtgat gtcttcaccc
     5401 gggtttttac cggacagcac gaagcgggtt aaaccacggt gtgcgaaaaa ggtcatcggg
     5461 aaagcgagaa tcgccatgat gatgagcgga atcatgccgc cgacgcctgc gttgatcggc
     5521 aggaacagaa cgcccgcgcc gattgccgtg ccgtaaaggc ccagcatcca catggtatcc
     5581 gttttgcgcc atgcgcttcg agagtcaatc gaagcaatcg tgctggtctg agtggttttc
     5641 atctatttct cctggaggat gctaaaaatc aggttgctgg tctaatccaa tgaaaaaaga
     5701 cctgatcgta aaatgaaatc tgcttaggga cgctttttat ataatttttc gccgtaataa
     5761 ttttcgggcg gaaagataca tttaagtgat gaatctatca gtgatcccga tctcaaatgc
     5821 aataatccgc ttcttacatg gataaatttg gaccattaat ctattaaaaa aacgtcataa
     5881 cgaatttccg ggcgcgaagg ctaccattaa cgatataagg ccggaaagat tggggcgcaa
     5941 gatacggagg tttgactata aaaatcaagg tttttagtgg attcttgcga agaatgagag
     6001 tttgaaccga taaatcacgg taagaggagt caggtaaacg tttgcctggc aatctattta
     6061 tggtaaatta taaatggtgt ttataaaaca atgcgggcta tacctctgat gatcatcata
     6121 aaaaatgaag gcatacgtga atcgccatac cgcaatgaaa ggaatgggag aagcgcccgg
     6181 ctgctggcgg caaccgggca taagcgttaa gcgcagatct cgtaacaggg gatgtaggcg
     6241 gaacccggca atttcatacg atgctgcgcg acgaatccct gcagcagatc gtccatgcga
     6301 cgcatcatct ctcgatcgcc gtggatttta tacggaccat tagcttcaat ggcgcgtatc
     6361 ccgacctcct tcacgttccc cgcgacaata ccggagaagg cgcgccgcag atccgccgcc
     6421 agaatctcaa ccggctgatc cgggtacagt ttcaggttgg ccatattctc atgcgacggc
     6481 tcaaacggca cctgcagatc cggtgcaata cgcatcgacc agttaaaact ataggcgtcg
     6541 ccagtatcgc ggcgattctc tttcacttgc ggcatcgctt tcttcatcag ccgcgctacc
     6601 tccgccgcat cgtcaatgat gatgcggtaa tgacggcggg ccgcttcgcc cagcgtatgg
     6661 gtaataaact catccagcac gcggaagtaa tcggcgctct cttttggtcc ggtcaggatc
     6721 agcggcagca cctgattttt attggctgga ttcatcagaa tccccagcaa ataaagcagc
     6781 tcttccgccg tacccacgcc gcccgggaag atgatgatac cgtgtgcgat acggacgaac
     6841 gcttccaggc gtttttcgat atccggcatg atgatcagtt cgttcaccag cgggttaggc
     6901 ggttcagccg caataatgga aggttcagtc atgccgataa agcggctgtc tttatagcgc
     6961 tgctgtgcgt gaccgaccgc cgcgcccttc atgggggctt ccatcgcccc agggccgcag
     7021 ccggtgcaga tgttcagctc gcgtaatccc aactgcgtgc cgacgcgacg ggcatacagg
     7081 tactcgtttt cgttaattga gtggccgccc cagcatacca ccatgtttgg cgcttcgccg
     7141 acgtgcagcg cccgggcgtt gcgcaaaatg gagaacacca gattggtgat atgtgttgag
     7201 ctttcaagat ccagatgctg gaaacggccg gcattgtgga tctgcccatt cacaaagaga
     7261 atgtcgcgca gcactgcgaa caggttagcc tgtagcgcac gaataatccg cccgtcaaca
     7321 aaggcgtctt caggcggatt aatcaattcc agcttcacgc cgcgctcgcg gcgcagtacg
     7381 ttaatatcga aattttcaaa gcaggacagc agctctttgc tgttgtcggt caggctgccg
     7441 gagttaagaa cggcaagtga acagttacga aacagttgat acaggtcgct actggccgtg
     7501 cgtttcagca tgtccacttc cagttgcgac aacatatcca ttgagccaag cgggctaata
     7561 tgtgtaatca agtaaactcc ttatgggacg caacacgcca ttccctgttg attacaatag
     7621 ccctggctga tgacctttca caaccttaca tgcgcaatcc ggcacgcaaa attgacaaaa
     7681 aagattactg acgcgccagc ctgcccgtgg cgggcacaaa atcggtattg ctgcgccagg
     7741 gattaatgtc cagcccgccg cggcgggtat agcgtgcata aacgcttaac gtttccggct
     7801 ggcagaagcg cagaatgtca ttgaaaatac gctctacgca ctgctcgtga aattcattat
     7861 ggtgacggaa ggagaccaga taacgcagca gtttttccct gtcgattttg cgcccgcgat
     7921 actgaatttg tatcgagccc cagtccggtt ggtgggtgat caggcagttg gatttcaaca
     7981 gatgactgac cagcgtttct tctacttgct tctcgccgct gaccgcatgt tgcagatagt
     8041 cggtagtaaa ctggtagttg tcgatactga tatcctgatc gtcaatacag gtgccgtgga
     8101 aatgggcgac aggctgtcct tccagctcat caagacgatg aagcctcacg ctaacgttgc
     8161 cctgcgcgca ggcgcgcaga tcgcgctcca gcgtctggcg caccgtctcc caggtgtcaa
     8221 agcgcgtctg gttaaagctg ttcagataca gtttaaaact tttggattcg attaaattaa
     8281 cgctggtgta atccagttcg acatgtccga cggcgacctg cggaagaccc tggctgttaa
     8341 gccaggaaag ttcatacaac gtccagatat ccgcgccgtg gaacggcaaa ttatcggctg
     8401 ttaatccgag cgggtcgcga ttcaaactgc gcggtacgcc ctgcagcagg ctggcgtcat
     8461 aattgtcccg gtaatccgtt gattttccga gagtcaggcc atcgagagcc tgatggtttt
     8521 cataagaaga catgtttcac cgtcataaac cagatacact atgcgtcaag tgtatcctgg
     8581 cttttatgaa gagagaaact ggtggacgaa ctgacagcgc aggcattgaa agcctttacg
     8641 acgcgttact gcgacgcgtg gcaagaaaaa cacggtagct ggccgttgag cgaagaactg
     8701 tatggcgtac cttctccgtg cattatttct tcaacccgcg atgccgttta ctggcagccg
     8761 cagccttttg aaggcgaaga aaatgtaaac gcggttgaac gcgcctttga tattatggta
     8821 caacctgcgc tccacgcgtt ttacaccacg cagtttgctg gcgacatgcc cgcgcagttt
     8881 gcggatgaaa agcttacgct actgcaaacc tggagtcagg atgactttcg gcgcgtgcag
     8941 gaaaatctga taggccacct ggtcacgcaa aagcggctca agcttcctcc cacgcttttt
     9001 attgcgacgc aggaaaatga gcttgaggtc atttcggtct gtaatctgtc cggcgaggtg
     9061 attaaagaaa cgctgggcac ccgcaatcgt accgttcttg ccgcaacgct tgcggaattc
     9121 cttacgcaac ttaatcctct tctgtaatcg tttgccctaa cgggtgtgag agatctctta
     9181 caaagtctgt aggagatcgc caggatatca gcggatactg agccccgttt tcttatgtaa
     9241 gtctatataa aacaactaat taaaatgttt ttgcgcactt tcatatgaaa atttacttaa
     9301 ggtattgtct gtaagcgtct tgtaagacaa ggtgaaacag gcgattctat cttcgtcgac
     9361 agggagtcgt acaacgaagc gaacgtcagg atgatgacgc ttcagcagga cacgccagga
     9421 tggtgttaca aggaaaggct tcaggatgaa gcaaagtgga aagcgcagga tgcgttaaag
     9481 gacacctcca ggacggagaa cgagagccga tcaggatgtt cggcggatct ggataaccag
     9541 ggacgcttca ggatgaagct atcacatcgg gcgatgtgcg caggatgtaa acgttcagga
     9601 tgaacaggcc gtaaggtcac aggaaaagtt gtcacggatg agcagggagc acgaaaagta
     9661 gctggaatgc tgcgaaacga accgggagca ctgtttatac agtgctccct ttttttgtta
     9721 ttcttcgcgc cagattttca tcattgaggt tttaacatga cgactcatga ccgtgtgcgt
     9781 cagcagttac atgcgcttga aacgctgctg cgcgagcatc gccactggcg gctggatgcg
     9841 ccgcaggcgc atttgtttac cagcacccaa ccatttttta tggataccat ggaaccgctg
     9901 gaatggctgc aatgggtatt gatcccacgt atgcataccc tacttgataa tgcgcagccg
     9961 ctgcccgagg cgtttgccgt cgccccttat tatgaaatgg cgctggcggc ggatcatccg
    10021 cagcgggagg cgatcctggc ggttttgcag gatctggatg cgctattcgt ccgcgataaa
    10081 tcctgatgct ggagatcctc tatcaagacc cgtggctggt tgccgtgaat aaacccgcag
    10141 gctggcttgt tcaccggagc tggctggatc gcgacgaaaa agtcgtggtc atgcaaacgg
    10201 tgcgcgacca aatcggccag catgttttta ccgcccaccg tctcgacagg cccacgtcgg
    10261 gcgtactgtt aatggggctg tccagcgaag cgggacgccg tctggcgcag cagttcgagc
    10321 agcaccacat ccgtaaacgc taccatgcca ttgtgcgcgg ctggctgata gatgacgcgg
    10381 tactggatta tccgctggtg gaagagcgcg ataaaattgc cgataaattc gcccgcgaag
    10441 ataaagcgcc ccagccggct gtaacgcagt atcgcgggct ggcgacggtc gaaatggcgg
    10501 tgccgaccgg gcgttatccc accacgcgtt atggcctggt tgagctggaa ccaaaaacgg
    10561 gacgcaagca ccagcttcgt cgtcatctgg cgcatctgcg tcatcctatc atcggcgaca
    10621 gcaagcatgg cgatttgcga caaaaccgca gcgccgcaga gcattttgcc tgtcgtcgcc
    10681 tgatgcttca tgccagtcgg cttgaactga cgcacccctt caccggacag ccgttgataa
    10741 ttcaggccgg gttggatgaa acctggatgc aggtgctgac acagtttggc tggcgtggac
    10801 ttctccctga caatgaaagg gttgagttta cggcggcgtc ccggcaggat gagactcatc
    10861 tgacataatt cagggagata cgcataatgg cggaaattgg tatttttgtc gggaccatgt
    10921 atggcaactc actgctggtg gcggaagaag cggaagcgat cctcgccaga cagggccaca
    10981 gcgcgaccgt gtttgaagat cctgaactgt ccgactggca gcaatatcag gataaggttg
    11041 cgctggtcgt tacctcgacg accgggcaag gcgatctacc ggatagcatt gcgccgctct
    11101 ttcacggcat taaagatacg ttgggttttc agccaaacct gcgttacggg gtgattgcgc
    11161 taggtgatag cagctacccc aatttctgta atggcggcaa acagtttgat gccctgttgc
    11221 aagagcaaag cgcgcagcgg gtgggggaga tattattcat tgacgccagc gaacatccgg
    11281 agccggagag ccaatccaat ccctgggttg aaaactgggg aactttactt tcctgaggta
    11341 aatccctccc ccctacggga gggtaccttt tcgtttgctt gcgttgccag taagcaaaat
    11401 cacgacctgt acacagtgta aagtaactga atcgtgttag ctttgggcat atgcccgcaa
    11461 aagcggcagt tttttacggg cgttttcatg taatcaagcg acctgtttca cattcttctc
    11521 tttttactcc tcctgcgtcg acgccgacgc cttctgattt catttccgtg aagtggcttc
    11581 cactgtcctg ggcttttgcc ataaacaggc gtaattcatc gccaaaatac tgtgttgttg
    11641 cacggtgagt gtgtgtggcg cgctttttat acttctcctg ccagtgaata aaagcatgca
    11701 gcgtgcaaag caaacgacct aataaaagct gcaacaagga aacgttatct ctgattccct
    11761 accggttgtg cagttcagag tgagcgtagc taacgcgaaa tttcaggagt gcaacaatga
    11821 gttcattaag tcacgcggcg agcagtgcgg agaaacgcac gaacgcccgc tactggatag
    11881 tggtgatgct gtttatcgtc acatccttca actacggcga ccgcgccaca ttgtccattg
    11941 ccggctcaga aatggccaaa gatatcggcc ttgatccggt aggtatgggc tatgtttttt
    12001 ctgctttttc atgggcctat gttatcgggc agatcccggg cggctggctg ctggaccgct
    12061 ttggttccaa acgcgtctat ttctggtcta ttttcatttg gtcagtcttc accctgttgc
    12121 agggttttgt cgatatcttt agtggtttcg gcattattgt cgccctcttt acgcttcgtt
    12181 tcctggtcgg tctggcggaa tcgccttctt tcccgggcaa cagtcgcatc gttgcggcct
    12241 ggttcccggc gcaggagagg ggaacggcgg tggccatctt taactccgcg caatactttg
    12301 ccacggttat tttcgcgccg attatgggct ggctgacgca cgaagtgggc tggtcgcatg
    12361 tcttcttctt tatgggcggg ttagggatca tcatcagctt tatctggttg aaagttatcc
    12421 atgaaccaaa taaccatccg ggcgtaaata agaaagaatt ggagtacatc gcagaaggcg
    12481 gcgcgctgat caatatggat cagaaagaca ccaaagcgaa agtaccgttt agcgtcaaat
    12541 ggggccagat caaacagctg ctgggctctc gtatgatgat tggcgtttac atcggtcagt
    12601 actgtattaa cgcattgacc tatttcttta ttacctggtt cccggtctat ttggtccagg
    12661 cgcgcggcat gtcgattctc aaagcgggct ttgtcgcctc ggttcctgca gtctgcggct
    12721 ttatcggcgg cgtgttgggc ggcatcattt ccgactggct gatgcgtcgt actggcttcc
    12781 tgaatatcgc gcgcaagacg ccgattgtgc tgggaatgtt gctgtcaatg gttatggtgt
    12841 tctgtaacta tgtgaacgtg gaatggatga tcatcggctt tatggtgttg gccttcttcg
    12901 gtaaaggtat tggcgcgttg ggctgggcag taatggcgga taccgccccg aaagagatca
    12961 gcggtctttc cggcggcttg tttaatatgt tcggcaatat ttccggtatt gtgacgccaa
    13021 tcgcgattgg ttacatcgtt ggcaccaccg gttccttcaa cggcgcgttg atctatgtcg
    13081 gcgtacatgc cctggtggcc atcatcagct atctggtgct ggtaggcgat attaagcgta
    13141 ttgaactgaa acctgtcgca ggacaattat catgacaacg caatccagtc ccgttattac
    13201 ggacatgaag gtcattccgg ttgccggaca tgacagtatg ctactcaaca tcggcggcgc
    13261 gcataacgcg tacttcaccc gtaacatcgt cgtcctcacc gataacgccg ggcatactgg
    13321 cgtcggcgag acgccgggcg gagaagtgat ttatcagacg ctggtcgatg ctattccgat
    13381 ggtattaggc caggaagtcg cccgcctgaa caaagtggtg cagcaggtgc ataaaggcaa
    13441 ccaggccgct gattttgaca cctttggcaa aggcgcatgg acgtttgaac tgcgggttaa
    13501 cgcggtggcg gctttggaag cggcgctgct tgatctacag ggacaggcgc ttaatgtgcc
    13561 ggtctgtgaa ctgttagggc caggtaaaca gcgcgatgcc gtcaccgtgt tgggctatct
    13621 cttctatatt ggcgatcgca ctaaaaccga tctgccgtat ctggaaagca cgccgggcag
    13681 tcatgaatgg tatcgtctgc gccatcagga agcgctgaac agcgacgcgg tcgtgcggct
    13741 ggcggaagcg tctcaggatc gctacggctt taaagatttt aaactcaagg gcggcgtgct
    13801 gccgggcgaa caagagattg ataccgttcg cgcgctaaaa aaacgcttcc cggacgcgcg
    13861 tattaccgtg gatccgaacg gcgcctggct actggatgaa gccattgcgt tgtgcaaagg
    13921 gctgaatgat gtactgacct acgcggaaga tccgtgcggc gcggagcaag gattctctgg
    13981 tcgtgaagtc atggcggagt tccgccgcgc gacaggactg ccggtggcga ccaatatgat
    14041 tgccaccaac tggcgtgaaa tgggacacgc ggtgatgctc aacgcggtag atattcctct
    14101 tgccgacccg catttctgga cccttaccgg cgccgttcgc gtggcgcaac tgtgcgatga
    14161 ctgggggcta acctggggct gccattcgaa taaccatttt gatatttcac tggcgatgtt
    14221 tacccatgtc ggcgcggcgg cgccaggcaa acccaccgct attgatacgc actggatctg
    14281 gcaggagggc gattgccgcc tgactaaaaa tccgctggaa attaaaaacg gcaaaattgc
    14341 cgttccggat gcgccaggac tgggcgtaga gcttgactgg gaacaggtgc gaaaagcgca
    14401 tgacgcgtat aaaaagctgc caggcggcgc gcgtaatgat gcaggcccga tgcaatacct
    14461 gatccccggc tggacttttg accgcaaacg ccctgttttt ggtcgtcact aattctgaat
    14521 aaggacacag ttatgagtac tcaatttacc acgcctgtag tgactgaaat gcaggttatc
    14581 ccggttgcgg gtcatgacag tatgctgatg aacctgagcg gcgcgcacgc cccgttcttt
    14641 acgcgcaaca tcgtcattgt taaagataac tccggtcata ctggggtcgg cgagattccg
    14701 ggcggcgaaa aaattcgcaa aacgctggaa gatgcgattc cactggtggt gggaaaaacg
    14761 ctggatgaat ataaaaatgt cctgaccgcc gttcgcaacc agtttgccga tcgcgatgcg
    14821 ggcggacgcg gtttacaaac gttcgatctc cgtaccacta tccatgtggt gacgggcatt
    14881 gaagcggcaa tgcttgacct tttgggccaa catctgggcg tcaacgtcgc ttcgctgtta
    14941 ggcgacggtc agcagcgcag cgaagtcgaa atgctgggtt atctgttctt tgtcggcaat
    15001 cgcaaggtta cgccgctgcc gtatcaaagc cagccggatg agcaatgcga ctggtatcgt
    15061 ctgcgccatg aagaggcgat gacgccggaa acggtagtgc gtctggcgga agcggcgtat
    15121 gaaaaatacg gcttcaacga cttcaaactg aaaggcggcg tgctggcggg cgaagaagag
    15181 gccgagtcaa tcgtggcgct ggcgaaacgt ttcccacaag cgcgcgtcac gctcgatcca
    15241 aacggtgcct ggtcgctgaa cgaagcgatc agcattggta aatacctaaa aggttctctg
    15301 gcctatgcag aagatccgtg cggcgcggag cagggttttt ccggtcgtga agtgatggcg
    15361 gaattccgtc gcgcgaccgg attaccgacg gccaccaata tgatcgccac cgactggcgt
    15421 cagatggggc atacgctgtc gctgcaatcc gtcgatatcc cgctggcgga cccgcacttc
    15481 tggactatgc aaggctctgt acgcgtggcg caaatgtgtc atgagttcgg cctgacttgg
    15541 ggctcgcact ctaacaacca ctttgatatt tcactggcga tgtttaccca tgttgccgcg
    15601 gcggcgccgg gcaagatcac tgctatcgat acccactgga tctggcagga aggcaaccaa
    15661 cgtctgacta aagaaccgtt tgaaattaaa ggcggcatgg tgcaagtacc gaccaaaccg
    15721 gggctgggcg ttgagctcga tatggatcag gtgatgaaag cgcatgagct ctatcaaaag
    15781 catggcttag gcgcgcgtga cgacgcgatg ggaatgcagt acttaattcc tggctggacg
    15841 tttgataata agcgcccttg catggtgcgt taagtcagag ccggttccgt aaggaaccgg
    15901 tccttctctg ggtgtatgct taacaggatc aacatgcgta aggacgactt atgaaaatag
    15961 tgatcgcacc agattcgtat aaggaaagtt tgagtgctct tgaggtagcg accgccattg
    16021 aacaaggatt tcgcgagatc tggcctgacg cggattacct gaaattaccg ctggctgatg
    16081 gcggagaagg tactgtcgaa gcgatggttg aagcgacggc gggtcgaatc gtgcatgttg
    16141 aggtcaccgg gccgttgggg catcgcgtca atgcgtttta tgggctttcc ggcgatgcgc
    16201 gttccgcgtt cattgaaatg gcggccgcca gcgggctgga gcaggtgccg cccgcgcaac
    16261 gcgatccgtt gaagaccacg tcatggggaa ccggcgagct gatccgtcat gcgctggatg
    16321 cgggcgttga gcatatcatt attggtatcg gcggtagcgc caccaacgat ggcggcgcgg
    16381 ggatggtaca ggcgctgggt gccaggctac gggatgcgca gggcaatgat attgcgcaag
    16441 gcggcattgg gctggaaaca ctcgccagca ttgatatcag cggcctggat aagcgtttgt
    16501 cggcgtgcca tatagaggtc gcctgcgatg tcacgaatcc ccttaccggc aaagagggcg
    16561 cgtctgcagt ttttggtccg caaaaagggg cgacgccgga aatgattgaa cgcctagata
    16621 cggcattgac tcgctatgcg catttgattg cccgcgatct gcatgtcgat gtgttggatc
    16681 tggcaggcgg cggcgcggca ggcggcatgg gggcggcgtt atacgcgttt tgcggcgcgc
    16741 agctacggcg tggtattgag attgtcaccg atgcgcttca tctggaagcg tgtcttgcgg
    16801 atgctgattt agtcatcacc ggcgagggac gcatcgacag tcagaccatt cacggtaaag
    16861 tccctattgg cgtggcaaac atcgccaaac ggtataacaa gccggtaatt ggtattgcgg
    16921 gtagcctgac ggcggacgtt ggcgtggttc atgaacatgg gcttgatgcc gttttcagcg
    16981 tgatttatac catctgcacg ttggaggacg cgctgaagaa tgcgagtgaa aacgtacgaa
    17041 tgaccgcgcg caacgtggct gcaacgctga aagcggggca acaattacgc tgagttgtag
    17101 gccggataag gcggtcacgc cgccatccgg cgaatatcag cctaatatct tcttcgcttc
    17161 acgcgcgaca ttatccatct catccagcag ctccagaaac tcaggctcca gctcctcttc
    17221 gtggacgccg ctgcgaagct gttgctcaat aagctggcaa aggttcttca tccgcggtac
    17281 gccgctatag ccgcagctcc cgtgtagctt atggaccaga tcgaccaggc cgttgggatt
    17341 ctctcccacc agttgttctt caattttgtt gcgcacttcc ggcagaaaat caatcagcat
    17401 ttgcagcata tcccgtgcca gatcgggctt accggcagcc tggcggagcg caagctgcca
    17461 gtcgagcgtc gcattcggat tgaagataaa ctcagccggt tccggcgcca tcaggcgcgc
    17521 tgctacgttg gcgccgggtt tatagcgcag caacagatta tgcaacttct cttcttctat
    17581 cggtttagcc agatagtcgt tcatgcccgc gctgagcaac ttctcttttt gcccggccat
    17641 cgcatgtgcc gtaacggcaa taaccggtgt ttgctgctga tgaggaagct ggtgaattaa
    17701 ctcgcaggcg cgtatgccgt ccatatccgg catctgaata tccatcaaaa tcagatcaaa
    17761 ctgcatttgt ttcgcccgat ccaccgcctg atgtccgcta tcacaaagct ctacgtgctg
    17821 gactttatct tccagtaacg cgccgataag cttcagatta gcgggattat catcaaccgc
    17881 cataaccgtc atggtgattt tactggtatc cattagcagc ggttcaggat ggtgattcaa
    17941 ctggcaatat tctgtcagcg ctggcaacag gcgcgttgac gtcaatggtt ttaacagaca
    18001 ggctgccgcg cctccttgtt tcagcttttc ggcattaatt tgcgcatggc aaggtagcgc
    18061 cagcagtaga aagtccgtca ttgacgctgc tttcgccaga cgttcatgct gcatggtgag
    18121 cggctcgcgg aaggtcaccg gaacgctcaa aatcataata tcgtagtgcg ctaacggcag
    18181 cgcggagaag gtcgggctgt aaatcacttc caccggcgtg tcgctcagta gatccagggt
    18241 acattgcgcg gcggtagcat tcggttcgat ataagccagc cgtttcccgg ccagacacgc
    18301 ggtcgacggc ccgtcaataa tgacatttgg gttaagatca agattaatat gaaaccagaa
    18361 ggtcgagccg cgattaggct ggctgtggaa agagatatcc ccgcccattt cgttgaccag
    18421 cttttgcgta atcaccagcc caagcccggt gccgccgtga cggcgagaaa tactggcatc
    18481 ggcctggcga aacgcctgaa acagtcgcga ctggtcgcgc tccggaatgc cgatccccgt
    18541 atcgcggatc tgcacttcaa tctgtacttt ggtgttactg agcgcccgct tttctaccag
    18601 aatgtcgata ttgccactct cggtgaactt aatggcattg cccaccagat tagtaatgac
    18661 ctgttgcagg cgcagcgggt cgccaatcac attttccggg acgtcgtttt taatatttaa
    18721 cgtcaactcc agccctttat catgcgacga gtgggccagc agcgtaacca cttcatccag
    18781 cgtgttgcgc agtggaaaag ggatactttc cagaatgagc ttaccggctt ccagcttgga
    18841 gaagtcgagc acgtcattaa tgattgccag cagattattc gcggaacgct caatggtgtt
    18901 cagatggtcg cgctgggtgg ggttcagctc cgtttttaat gtcaggcggg taaaaccaat
    18961 gacgccgttc agcggtgttc gcagttcgtg cgacatgttc gccaggaact ccgacttaat
    19021 acgcgccgct tcctgggcgc gctttttcgc cagatccagc tcaacgtttt ggatttccat
    19081 ctgctcaagg gtttcacgca ggtccgaggt ggcctgatcg atattatgct gcatctcttc
    19141 gtgataggcg gcaagcgaca tcgccatgga attaatgccg tttttcagca tgtccagctc
    19201 gcccagcata aatccttcca cacggctatc cagttgtccg cggcgaatgc ggtcaacggt
    19261 attcaccata ttacggatag gcccggtgac atcgcgcata agccgccagc caaagatcag
    19321 cgcaatgcca atacaaaaaa gcatcatcac gctggagata aaaatctctt tgtattgctg
    19381 tagcctgacc gacttgagat ccagttcaag tgccacatac cccagcatat ttttggtatt
    19441 tttcgcgtcg gcaatcgctg actcgtccgg cgaatagctc tccgagataa tcggggtgcg
    19501 cagaatcata atatcgccgt ggcgatcaac gctcagacga cgtggaaacg gcgctccggc
    19561 aggaagctgc atctgtgagg ggtccagatg gaaattagac gttacaaaca ggcggttatg
    19621 atcgtcataa acggaaatcg cccgcacaat atcagagtgt ctgcggtgca ggacgctgat
    19681 aagttggccg atagactccc ggttttgtaa gttcatacca tattcgctgg agacggcgag
    19741 cggttcaata atactggcgc cggcatcttc cagttgacgc tgcaggtcgt tatagcggtg
    19801 cactacaaaa aagatactga gcagcaaacc tatcaggacg gtcggggcca ggatcagaat
    19861 catcatgcgt gcgcgcaggc tgtagttggt catggagttc cgttatggga caattagggt
    19921 cacactgtta aattgagaaa aagctggtcg atggcgcaat tctactctgc aaaacggcgc
    19981 gtgacgacgc gtcagatcat aaccgttaaa gtcaatgacc tcgattcatt tggtcagggc
    20041 gtagcccgtc ataacggaaa ggcgctgttt atccccggtt tattgcctga ggaaagcgca
    20101 gaagtcatta ttacagaaga taaaaagcaa tttgcccgcg cacgcgtttc gcgccgtttg
    20161 aatgatagcc cggaacgaga aacgccgcgc tgcccgcatt ttggcgtctg cggcggttgt
    20221 cagcaacagc atgtcggcat cgacctgcaa caacgcagca aaagcgcggc gctggcgcgt
    20281 ttaatgaaac atgaggtgaa tgacatcatc gccggcgcgt cctggggtta tcggcgtcgt
    20341 gcgcggttaa gtctgaattg cccgccggat aaaccgctgc aaatgggatt tcgcaaagcg
    20401 ggttccagcg atatcgtcaa tgtcgaacag tgccccgttt tggcgcccca gcttgaagca
    20461 ttgctgcccc gcatcagggc gtgtctggcg agtttacacg gcacccgaca tcttgggcat
    20521 gttgagctgg tacaggcggg aagcggtacg ctgatgattc tgcgccatac cgcgccatta
    20581 agtgcggcgg ataaagaaaa actggaacgc ttttcgcatt ctgagggatt gtctctgttc
    20641 ctggcgccgt ttagcgagat actggaaacg gtatctggcg aagcgccctg gtatgattcg
    20701 cacggcttac gtttaacctt cagtccgcga gactttattc aggttaatga ggcggtaaac
    20761 cagcaaatgg tcgcccgcgc gctggagtgg cttgatgtgc gcgccgagga tcgtgtcctg
    20821 gatctgttct gcggaatggg gaattttacg ctaccgctgg caacgcgcgc ggcaagcgtg
    20881 gtaggggttg agggcgttca ggcgctggta gaaaaaggcc gtgaaaacgc catccgcaat
    20941 ggtttacata atgtgacatt cttccacgag aacctggagg aagatgtcac gaagcagccg
    21001 tgggcgaaaa acggctttga caaagtctta ctcgatcctg cgcgtgcggg ggctacagga
    21061 gtgatgcgac atattataaa attaaaacct attcgcattg tttatgtatc ctgtaacccg
    21121 gcgacgctgg cgcgcgatag tgaagcgctg gtcaatgcgg gatatgaggt tacgcgttta
    21181 gcgatgctcg acatgttccc gcacacagga catctggaat caatggttct gttcgagcgc
    21241 atgtaatgat taccggctta ccgacttcgg taggcctggt cccttaagga gaggacgatg
    21301 gtcgcggtaa gaagtgcaca tattaataaa gctggtgaat ttgatccgaa gaagtggatc
    21361 gcaagcctgg gaatttccag ccagcagtcg tgtgagcgct tagccgaaac ctgggcgtat
    21421 tgcctgcaac agacacaagg acatccggat gcggatctgt tgctgtggcg tggcgtggag
    21481 atggtagaaa ttctttccac gctgagtatg gatatcgaca cgctgcgggc ggcgctactg
    21541 ttccctctgg ccgacgccaa cgtagtcagc gaagatgtac tgcgcgaaag cgttggcaaa
    21601 tctatcgtta ccctgattca tggcgtgcgc gatatggcgg cgatccgcca gttaaacgcc
    21661 actcataacg actctgtttc ttcggagcag gttgataacg tccgtcgaat gttattggcg
    21721 atggtggatg atttccgctg cgtggtcatc aaactggccg agcgaatcgc tcatttgcgc
    21781 gaagtgaaag aggcgccgga agatgagcgc gtgctggcgg cgaaagaatg taccaacatc
    21841 tatgcgccgc tcgctaatcg tctgggcatc gggcaactga agtgggaact ggaagactac
    21901 tgtttccgct acctgcatcc ggcggaatac aaacgcatcg ccaaactgct gcatgaacgc
    21961 cgcctcgatc gcgaacatta catcgaagag tttgttggac atctgcgcgc cgaaatgaaa
    22021 aacgaaggcg tgcaggcgga agtctacgga cgaccaaaac atatttatag catctggcgc
    22081 aaaatgcaga aaaagcatct ggcgtttgat gaactctttg acgtgcgcgc cgtgcgtatc
    22141 gtcgctgaac gtctgcaaga ctgctacgcc gcgttgggga tagtgcatac gcactatcgc
    22201 cacctgccgg atgaattcga tgattatgtc gctaacccga aaccgaacgg ttaccagtct
    22261 atccacaccg tggtcttggg gccgggcggt aaaaccgttg agatccagat ccgtaccaaa
    22321 cagatgcatg aagacgccga actgggtgtg gcggcgcact ggaagtataa agaaggcgcc
    22381 gcgtccggcg gcgtgcgttc cggccatgaa gacagaattg cgtggctgcg taagctgatc
    22441 gcctggcagg aagagatggc cgattccggc gaaatgctgg atgaagtgcg cagccaggtg
    22501 tttgacgatc gggtctacgt ttttacgcca aaaggcgacg tggttgactt gcctgccgga
    22561 tctacgccgc tcgattttgc ttaccacatc cacagcgatg tcgggcaccg ctgcatcggc
    22621 gcgaaaattg gtgggcgcat cgtaccgttt acctaccagt tacagatggg cgatcaggtt
    22681 gaaattatca ctcagaagca gccgaatccc agccgcgact ggctgaatcc aaacctgggc
    22741 tatgtgacga ccagccgcgg acgctcgaaa attcacgcct ggttccgtaa acaggaccgt
    22801 gacaaaaata tcctggctgg acggcagatc ctcgacgatg agctggcgca tttggggatt
    22861 agcctgaaag aggccgaaaa acatctgctg ccgcgctaca actttaatga gctggaagag
    22921 ttgctggcgg cgataggcgg cggcgatatc cgtcttaatc agatggtgaa tttcctgcaa
    22981 tcgcagttca ataagccgag tgcagaggag caggatgcag cggcgctgaa acagcttcag
    23041 caaaaaacat acgcgccgca aaatcgtcgt aaagacgacg ggcgcgtggt ggtggaaggg
    23101 gttggtaacc tgatgcacca cattgcccgc tgctgccagc cgattccggg ggatgaaatt
    23161 gtcggcttca ttactcaggg gcgggggatt tccgtgcacc gggccgactg cgaacagctg
    23221 gcggaactgc gctcccatgc gccggagcgg atcgtagagg cggtatgggg cgaaagctac
    23281 tcggcgggat attcgctggt ggtgcgcgtc caggccaacg atcgcagcgg tttattgcgt
    23341 gatatcacca ccattctggc taacgaaaaa gtcaacgtgc tgggcgtcgc cagccgcagc
    23401 gacattaaac agcagatcgc caccattgat atgaccatcg agatctacaa cctgcaggtg
    23461 ctgggccgcg tgctcggtaa gctgaaccag gtgccggatg tgattgatgc acggcgactg
    23521 cacggggggt aaaccccaga cagtaataat gtagcggctt tgctactcgt tcagcaaagc
    23581 cgcattagcc aaccccataa gcatgatata tgaggtatgt ttttgacgta catttcattt
    23641 caggtgtact cttatgtaag atttatactt acagtggagg ctgttatggc cagaacaatg
    23701 accgttgatc ttggcgatga attgcgcgag tttattgaat cgctcataga atcaggtgat
    23761 tacagaacgc aaagtgaagt gatcagagag tctcttcgtc tgctgaggga aaaacaggcc
    23821 gagtcacgac ttcaggcgtt acgtgaactt ctggctgaag gtctgaacag cggagagccg
    23881 caggcctggg aaaaggatgc ctttttacgg aaggtcaaaa cagggatgat caaacccgat
    23941 gagaacggta aaattaacgc caaaggccag tgaagatctg gaaaatatct ggcattacgg
    24001 ctggcagcat tttggtgaaa tacaggccga tcgatatatt catcatctat cagaaatatt
    24061 cagcattatg agtgccaata acattggcac gcctcgacct gaactgggtg aatacattta
    24121 tgccttaccg tttgaaaggc atattatcta ttttatataa tcagttacgg aagttatcgt
    24181 gatacgtatt ctgagccaga atcagg
//
LOCUS       DAJVBX010000049        24204 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.049, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000049 DAJVBX010000000
VERSION     DAJVBX010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 24204)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24204)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24204
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.049"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            271..1410
                     /locus_tag="OPV72_001713"
     CDS             271..1410
                     /locus_tag="OPV72_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide export protein"
                     /protein_id="HCR9914046.1"
                     /translation="MMKSKMKLMPLLASLSLISGCTVLPGSNMSTMGKDVIKQQDADF
                     DLDRMVNVYPLTPRLVEQLRPRPNVAQPNMSLDQEIASYQYRVGPGDVLNVTVWDHPE
                     LTTPAGQYRSSSDTGNWAQPDGTMFYPYIGKVSVVGKTLSEIRSDITGRLAKYIADPQ
                     VDVNIAAFRSQKAYISGQVNKSGQQAITNVPLTVLDAINAAGGLTDMADWRNVVLTHN
                     GKEQRISLQALMQNGDLSQNRLLYPGDILYVPRNDDLKVFVMGEVKKQSTLKMDFSSM
                     TLTEALGNAEGIDLTTSNASGIFVIRPLKGEGGRGGKIANIYQLDMSDATSLVMATEF
                     RLQPYDVVYVTTAPVARWNRLINQLLPTISGVRYMTDTASDIHSW"
     gene            1416..1865
                     /gene="wzb"
                     /locus_tag="OPV72_001714"
     CDS             1416..1865
                     /gene="wzb"
                     /locus_tag="OPV72_001714"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight
                     protein-tyrosine-phosphatase Wzb"
                     /protein_id="HCR9914047.1"
                     /translation="MFNKILVVCVGNVCRSPTAERLLKRFHPSLTVASAGLGALVGKG
                     ADPAAASVASAHDLSLENHCARQISARLCREYDLILTMEKRHIAALCDIAPEMRSKVM
                     LFGHWDSEREIPDPYRKSRDAFEAVYTLLERSARQWAQALNAEQGKP"
     gene            1862..4021
                     /gene="wzc"
                     /locus_tag="OPV72_001715"
     CDS             1862..4021
                     /gene="wzc"
                     /locus_tag="OPV72_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase Wzc"
                     /protein_id="HCR9914048.1"
                     /translation="MTEKVKQSAAVTGSDEIDIGRLVGTVIEARWWVLGTTAIFALCA
                     VIYTFFATPIYSADALVQIEQNAGNSLVQDINSALANKPPASDAEIQLIRSRLVLGKT
                     VDDLDLDIAVTKNTFPLFGAGWERLMGRHNEMVKVTTFTRPETMSGQIFTLKVLGDKR
                     YQLVSDGGFSAQGVVGQPLNKDGVTMRVEAIDARPDTEFTVSKFSTLGMINNLQNNLT
                     VTETGKDTGVLNLTFTGEDRDQIRDILNSITRNYLQQDIAWKSEEAGKSLAFLAKQLP
                     EVRSRLDVAENKLNAFRQDKDSVDLPLEAKAVLDSMVNIDAQLNELTFKEAEISKLFT
                     KAHPAYRTLLEKRKGLEDKKAKLNGRVTAMPKTQQEIVRLTRDVESGQQVYMQLLNKQ
                     QELKITEASTVGNVRIVDPAITQPGVLKPKKALIILGSIILGLMLSIVGVLLRSLFNR
                     GIESPQALEEHGISVYASIPLSEWQKARDSVKTIKGIKRYKQSQLLAVGNPTDLAIEA
                     IRSLRTSLHFAMMQAQNNVLMLTGVSSSIGKTFVCANLAAVISQTHKRVLLIDCDMRK
                     GYTHELLGTNNVDGLSDILAGKGEIASCAKPTAIANFDLIPRGQVPPNPSELLMSERF
                     GELIAWASSRYDLVLIDTPPILAVTDAAIVGRHVGTTLMVARYAVNTLKEVETSLSRF
                     DQNGIQVKGVILNSIFRRATGYQDYGYYEYEYQSDSK"
     gene            4108..4950
                     /gene="wcaA"
                     /locus_tag="OPV72_001716"
     CDS             4108..4950
                     /gene="wcaA"
                     /locus_tag="OPV72_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis glycosyltransferase
                     WcaA"
                     /protein_id="HCR9914049.1"
                     /translation="MTTDNPLISIYMPTWNRQQLAIRAIKSVLRQDYRHWEMIIVDDC
                     SSSYQQLQQFVEELNDPRVRYTHNAMNTGACAVRNQAIMQAQGHYITGIDDDDEWTPN
                     RLSVFLAHKHQLTTHAFLYANDYVCEGEVYSQPASLPLYPKSPYSRRLFYKRNIIGNQ
                     VFTWAWRFKACLFDTELKAAQDYDIFLRMVVEYGEPWKVEEATQILHINHGEMQITSS
                     PKKFSGYFHFYRKHKDKFDRASKKYQLFTLYQIRNKRMTWRTLLTLLSVRNSKRLAAG
                     LRGR"
     gene            4953..5441
                     /gene="wcaB"
                     /locus_tag="OPV72_001717"
     CDS             4953..5441
                     /gene="wcaB"
                     /locus_tag="OPV72_001717"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis acetyltransferase
                     WcaB"
                     /protein_id="HCR9914050.1"
                     /translation="MLEDLRANSWSLRPCCMVLAYRIAHFCSVWRKKNVLNNLWAAPV
                     LVLYRVITECLFGYEIQAAATIGRRFTIHHGYAVVINKHVVAGDDFTIRHGVTIGNRG
                     ADSLACPVIGHGVELGANVILLGDITIGNHVTIGAGSVVLDSIPDHALVVGEKARVKV
                     ST"
     gene            5438..6655
                     /gene="wcaC"
                     /locus_tag="OPV72_001718"
     CDS             5438..6655
                     /gene="wcaC"
                     /locus_tag="OPV72_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis glycosyltransferase
                     WcaC"
                     /protein_id="HCR9914051.1"
                     /translation="MNILQFNVRLAEGGAAGVALDLHLRALQKGLTSHFVYGYGKGGK
                     KSVSHHRYPQVIKQTPRGTAIANIALFRFLNRDLFGNLDNLYRTVIQTSGPLVLHFHV
                     LHSYWLNLADIVTFCEKVKAQKPDVTLVWTLHDHWSVTGRCAFTDGCEGWKSGCQKCP
                     TLSNYPPVRVDRAHQLIDGKRQRFRDMLRLGCQFISPSQHVAEAFNSVYGAGLCRVIN
                     NGIDLATEAILAQLSPVPLNPGKPRIAIVAHDLRYDGKTDQRLVHDMMALGEKIELHT
                     FGKFSPFTGQNVVNHGFETDKRKLMSALNEMDALVFSSRVDNYPLILCEALSIGVPVI
                     ATHSEAAQEVLAKSGGQTFAATDVLRLAQRRKPEIAQAVFGATLDAFRMRSRVAYSGQ
                     QMLEEYVSFYQNL"
     gene            6630..7843
                     /gene="wcaD"
                     /locus_tag="OPV72_001719"
                     /pseudo
     CDS             6630..7843
                     /gene="wcaD"
                     /locus_tag="OPV72_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461057.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative colanic acid polymerase WcaD"
     gene            7856..8602
                     /gene="wcaE"
                     /locus_tag="OPV72_001720"
     CDS             7856..8602
                     /gene="wcaE"
                     /locus_tag="OPV72_001720"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis glycosyltransferase
                     WcaE"
                     /protein_id="HCR9914052.1"
                     /translation="MFLSVVTVAFRNYEGVVKTWRSLRNLARDPGLSFEWIVVDGGSE
                     DGTREFLQKRHGEFNLRFISEKDRGIYDAMNKGIALAQGRYTLFLNSGDAFHDDAALF
                     VRQLARQKGEAMYIGDALLDFGGGHKIRRKAKPGYYIYHSLPASHQAIFFPTAALKKY
                     PYDLQYHVSSDYALAARLYKAGYPFRRINGLVSEFSMGGVSTSNNLELCQDAKNVQRK
                     ILRVPGFWAQLSYLLRLKTTGKTKARYNKV"
     gene            8618..9172
                     /gene="wcaF"
                     /locus_tag="OPV72_001721"
     CDS             8618..9172
                     /gene="wcaF"
                     /locus_tag="OPV72_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis acetyltransferase
                     WcaF"
                     /protein_id="HCR9914053.1"
                     /translation="MQDLSGFTVPKGFRGANALKVQLWWAVQATLFAGSPQILYRWRA
                     FLLRLFGAKIGKNVVIRPSVKITYPWKLTVGDYAWIGDDAVLYTLGEINIGAHAVISQ
                     KGYLCTGSHDYTSAHFDINAAPIVIGEKCWLATDVFVAPGVTIGHGTVVGARSSVFKS
                     LPANAICRGNPAVVTRQRVQKVTP"
     gene            9196..10317
                     /gene="gmd"
                     /locus_tag="OPV72_001722"
     CDS             9196..10317
                     /gene="gmd"
                     /locus_tag="OPV72_001722"
                     /EC_number="4.2.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005128297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
                     /protein_id="HCR9914054.1"
                     /translation="MSKVALITGVTGQDGSYLAEFLLEKGYEVHGIKRRASSFNTERV
                     DHIYQDPHSCNPKFHLHYGDLTDASNLTRILQEVQPDEVYNLGAMSHVAVSFESPEYT
                     ADVDAMGTLRLLEAIRFLGLEKKTRFYQASTSELYGLVQEIPQKETTPFYPRSPYAVA
                     KLYAYWITVNYRESYGIYACNGILFNHESPRRGETFVTRKITRAIANIAQGLESCLYL
                     GNMDSLRDWGHAKDYVRMQWMMLQQEQPEDFVIATGVQYSVRQFVELAAAQLGIKLRF
                     EGEGINEKGIVVSVTGHDAPGVKPRDVIVAVDPCYFRPAEVETLLGDPSKAHEKLGWK
                     PEITLSEMVSEMVANDLEAAKKHSLLKSHGYEVAIALES"
     gene            10320..11285
                     /locus_tag="OPV72_001723"
     CDS             10320..11285
                     /locus_tag="OPV72_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-L-fucose synthase"
                     /protein_id="HCR9914055.1"
                     /translation="MNKQRIFVAGHRGMVGSAIVRQLAQRGDVELVLRTRDELDLLDG
                     RAVQAFFAGAGIDQVYLAAAKVGGIVANNTYPADFIYENMMIESNIIHAAHLHNVNKL
                     LFLGSSCIYPKLARQPMAESELLQGTLEPTNEPYAIAKIAGIKLCESYNRQYGRDYRS
                     VMPTNLYGPHDNFHPDNSHVIPALLRRFHEAAQSHAPEVVVWGSGTPMREFLHVDDMA
                     AASIHVMELAREVWQENTAPMLSHINVGTGVDCTIRELAQTIAKVVGYQGRVVFDAAK
                     PDGTPRKLLDVTRLHQLGWYHEISLEAGLAGTYQWFLENQQRFRG"
     gene            11288..11761
                     /locus_tag="OPV72_001724"
     CDS             11288..11761
                     /locus_tag="OPV72_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461052.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose mannosyl hydrolase"
                     /protein_id="HCR9914056.1"
                     /translation="MFLRQEDFAAVVRTTPLISLDFIVENGQGEILLGQRLNRPAQGY
                     WFVPGGRVCKDETLEAAFARLTQAELGVRLPLAAGTFYGVWQHFYDDNFSSEDFSTHY
                     IVLGFRLRVAESDLRLPDAQHGSYRWLTPEQLLAGDNVHENSRAYFSPDAPAVGL"
     gene            11758..12981
                     /gene="wcaI"
                     /locus_tag="OPV72_001725"
     CDS             11758..12981
                     /gene="wcaI"
                     /locus_tag="OPV72_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis fucosyltransferase
                     WcaI"
                     /protein_id="HCR9914057.1"
                     /translation="MKILVYGINYSPELTGIGKYTGEMVAWMAREGHEVRVITAPPYY
                     PQWKVGERYSAWRYRREEGEATVWRCPLYVPKQPSTLKRLLHLGSFALSSFFPLMAQR
                     RWKPDRIIGVVPTLFCTPGMRLLATLSGARTVLHIQDYEVDAMLGLGMAGKGKRGSVA
                     RLATAFERSALRNVDNVSTISRSMMNKAREKGVAAEKILFFPNWSEVARFQDVNDADV
                     TALRQQLGLPEGKKIVLYSGNIGEKQGLEKVIDAAERLRDRPLIFAIVGQGGGKARLE
                     NMARERGLLNIKFLPLQPYDALPALLKMGDCHLVVQKRGAADAVLPSKLTNILAVGGN
                     AVITAEPHTELGQLCARYPGIAVCVEPESTDALVDGISQALAMPKNNTTAREYAERTL
                     NKENVLRQFIADIRG"
     gene            12978..14420
                     /gene="cpsB"
                     /locus_tag="OPV72_001726"
     CDS             12978..14420
                     /gene="cpsB"
                     /locus_tag="OPV72_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461050.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanyltransferase"
                     /protein_id="HCR9914058.1"
                     /translation="MIMRQTKLYPVVMAGGSGSRLWPLSRVLYPKQFLCLKGDLTMLQ
                     TTICRLNGVECESPVVICNEQHRFIVAEQLRQLNKLTENIILEPAGRNTAPAIALAAL
                     AATRQHTDCDPLMLVLAADHAIANEEAFRDAVRGAMPYADAGKLVTFGIVPDLPETGY
                     GYIRRGDVVPGATDAVAFEVAQFVEKPGLETAQAYVASGDYYWNSGMFLFRAGRYLEE
                     LKKFRPDILAACEQAMRGVDPDLDFIRVDEEAFLACPEESIDYAVMERTADAVVMPMD
                     AGWSDVGSWSSLWEISAHTPEGNVHHGDVISHKTENSYVYAESGLVTTVGVKDLVVVQ
                     TKDAVLIADRHAVQDVKKVVEKIKADGRHEHHMHREVYRPWGKYDSIDAGERYQVKRI
                     TVKPGEGLSVQMHHHRAEHWVVVAGTARVTINGEVKLLGENESIYIPLGATHCLENPG
                     KIPLDLIEVRSGSYLEEDDVVRFEDRYGRV"
     gene            14531..15901
                     /gene="cpsG"
                     /locus_tag="OPV72_001727"
                     /gene_synonym="manB"
     CDS             14531..15901
                     /gene="cpsG"
                     /locus_tag="OPV72_001727"
                     /gene_synonym="manB"
                     /EC_number="5.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis phosphomannomutase
                     CpsG"
                     /protein_id="HCR9914059.1"
                     /translation="MTKLTCFKAYDIRGRLGEELNEDIAWRIGRAYGEYLKPKTIVLG
                     GDVRLTSEVLKMALAKGLQDAGVDVLDIGMSGTEEIYFATFHLGVDGGIEVTASHNPM
                     DYNGMKLVREGARPISGDTGLRDVQRLAEAGDFPPVNDATRGSYRQISMRDAYIDHLL
                     GYISVNNLTPLKLVFNAGNGAAGPVIDAIEARLKALGAPVEFIKIHNTPDGTFPKGIP
                     NPLLPECRDDTRKAVIEHGADMGIAFDGDFDRCFLFDEKGKFIEGYYIVGLLAEAFLE
                     KHPGAKIIHDPRLTWNTEAVVTAAGGTPMMSKTGHAFIKERMRTEDAIYGGEMSAHHY
                     FRDFAYCDSGMIPWLLVAELVCLKGQSLGELVRDRMAAFPASGEINSRLAEPAAAIAR
                     VEAHFAEEAQAVDRTDGLSMSFADWRFNLRSSNTEPVVRLNVESRGDIPLMEARTRTL
                     LALLNQ"
     gene            15955..17349
                     /gene="wcaJ"
                     /locus_tag="OPV72_001728"
     CDS             15955..17349
                     /gene="wcaJ"
                     /locus_tag="OPV72_001728"
                     /EC_number="2.7.8.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-phosphate glucose
                     phosphotransferase"
                     /protein_id="HCR9914060.1"
                     /translation="MTNLKKRERAKTNASLISMVQRFSDITIMFGGLWFICEVSGLPF
                     LYMHLLVALITLVVFQMLGGMTDFYRSWRGVKMSTELTLLLQNWTLSLIFSAGLVAFN
                     DDFDNRLATWLAWYALSSLGLVLCRSFIRFGAGWLRNRGYNTRRGAVAGDLPAGQALL
                     DSFRNEPWLGFEVVGVYHDPKPGGVSADWAGNFEQLIDDAKASRIHNVYIAMSMSDGA
                     MVKKLVRELADTTCSVILIPDVFTFNILHSRVEEMSGVPVVPLYDTPLSGINRLLKRA
                     EDIVLASLILLLISPVLCCIAPAVKLSSPGPVIFRQTRYGMDGKPSKVWRFRSMKVME
                     NDKVVTQATQNDPRVTRVGNFLRRTSLDELPQFINVLTGGMSIVGPRPHAVAHNEQYR
                     QLIEGYMLRHKMKPGITGWAQINGWRGETDTLEKMEKRVEFDLEYIREWSIWFDIKIV
                     FLTIFKGFVNKAAY"
     gene            17451..18929
                     /gene="wzxC"
                     /locus_tag="OPV72_001729"
     CDS             17451..18929
                     /gene="wzxC"
                     /locus_tag="OPV72_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid undecaprenyl disphosphate flippase
                     WzxC"
                     /protein_id="HCR9914061.1"
                     /translation="MSLRQKTISGVKWSAIATIVIIGLGLIQMTVLARIIDNHQFGLL
                     TVSLVIIALADTISDFGIANSIIQRKTIGHLELTTLYWLNVGLGIVVFAVVFWLSDAI
                     AHVLHNPDLAPLIKTLSLAFIVIPHGQQFRALMQKELEFNKIGMIETTSVLAGFTFTV
                     ISAHYWPLALTAILGYLVNSAVRTLLFGYFGRKIYRPGLHFSLASVSTNLRFGAWLTA
                     DSIVNYINTNLSTLVLARILGASVAGGYNLAYNVAVVPPAKLNPIITRVLFPAFAKIQ
                     DDTEKLRVNFYKLLSVVGIINFPALLGLMVVANNFVPLVFGEKWNSIIPILKLLCVVG
                     LLRSVGNPIGSLLMAKARVDISFKFNVFKTFLFIPAILIGGHLAGAIGVTLGFLVVQI
                     INTILSYFVMIKPVLGSSYRQYILSLWLPFYLSLPTFITSYGAGKLVDGYLPLSGVFA
                     LQVVVGILSFILMIIFSRNALVMEIKNQLVGSEKMKKLLRVG"
     gene            18951..20229
                     /gene="wcaK"
                     /locus_tag="OPV72_001730"
                     /pseudo
     CDS             18951..20229
                     /gene="wcaK"
                     /locus_tag="OPV72_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461046.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis pyruvyl transferase
                     WcaK"
     gene            20226..21446
                     /gene="wcaL"
                     /locus_tag="OPV72_001731"
     CDS             20226..21446
                     /gene="wcaL"
                     /locus_tag="OPV72_001731"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis glycosyltransferase
                     WcaL"
                     /protein_id="HCR9914062.1"
                     /translation="MKVSFFLLKFPLSSETFVLNQITAFIDMGHEVEIVALQKGDTQH
                     THAAWEKYGLAAKTRWLQDEPQGRLAKLRYRACKTLPGLHRAATWKALNFTRYGDESR
                     NLILSAICAQAGQPFVADVFIAHFGPAGVTAAKLRELGVLRGKIETIFHGIDISSREV
                     LSHYTPEYQQLFRRGDLMLPISDLWAGRLKSMGCPPEKIAVSRMGVDMTRFSHRPVKA
                     PGMPLEMISVARLTEKKGLHVAIEACRQLKAQGVAFRYRILGIGPWERRLRTLIEQYQ
                     LEDVIEMPGFKPSHEVKAMLDDADVFLLPSITGTDGDMEGIPVALMETMAVGIPVVST
                     VHSGIPELVEAGKSGWLVPENDAQALAARLAEFSRIDHDTLGSVIMRAREKVAQDFNQ
                     QAINRQLASLLQTI"
     gene            21457..22860
                     /gene="wcaM"
                     /locus_tag="OPV72_001732"
     CDS             21457..22860
                     /gene="wcaM"
                     /locus_tag="OPV72_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis protein WcaM"
                     /protein_id="HCR9914063.1"
                     /translation="MPATKFSRRTLLTAGSALAVLPFLRALPVQAREPRQTVDIKDYP
                     ADDGIASFKQAFADGQTVVVPSGWVCENINAAITIPAGKTLRIQGAVRGNGRGRFILL
                     DGCQVVGEQGGSLHNVTLDVRGSDCVIKGVTMSGFGPVAQIFIGGKEPQVMRNLIIDD
                     ITVTHANYAILRQGFHNQMDGARITHSRFSDLQGDAIEWNVAIHDRDILISDHVIERI
                     DCTNGKINWGIGIGLAGSAYDNSYPEDQAVKNFVVANITGSDCRQLVHVENGKHFVIR
                     NVKAKNITPDFSKNAGIDNATIAIYGCDNFVIDNIDMTNSAGMLIGYGVVKGKYLSIP
                     QNFKLNAIRLDNRQVAYKLRGIQISSGNAPSFVAITNVRMTRATLELHNQPQHLFLRN
                     INVMQTSAIGPALKMHFDLRKDVRGQFMARQDTLLSLANVHAINENGQSSVDIDRINH
                     QTVNVEAVNFSLPKRGG"
     gene            23038..23931
                     /gene="galF"
                     /locus_tag="OPV72_001733"
     CDS             23038..23931
                     /gene="galF"
                     /locus_tag="OPV72_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GalU regulator GalF"
                     /protein_id="HCR9914064.1"
                     /translation="MMNLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEI
                     VAAGIKEIVLVTHASKNAVENHFDTSYELESLLEQRVKRQLLAEVQSICPPGVTIMNV
                     RQAQPLGLGHSILCARPVVGDNPFIVVLPDIIIDDATADPLRYNLAAMVARFNETGRS
                     QVLAKRMKGDLSEYSVIQTKEPLDNEGKVSRIVEFIEKPDQPQTLDSDLMAVGRYVLS
                     ADIWAELERTEPGAWGRIQLTDAIAELAKKQSVDAMLMTGDSYDCGKKMGYMQAFVKY
                     GLRNLKEGAKFRKSIEQLLHE"
BASE COUNT         5541 a         6041 c         7010 g         5612 t
ORIGIN      
        1 atttttatct gaacgaggat gaaattggag gggaatgcga aaatttagaa taatcagtgt
       61 attggtagct aagaagctag gggcggtagc gtgcctgaaa gcctgaatat aagactttat
      121 tattctgtca atagcctgcg gatgaattga tttttttcag aatgatgcca gttaattttc
      181 tctgccatta actgcaaggt aaatgtgcac ggacgaagcc gctatttaaa ttgcacagga
      241 taatgactct gccaaagtga taaataatca atgatgaaat ccaaaatgaa attgatgcca
      301 ttattggcgt cgctcagctt gataagtggt tgcacagtac tcccgggcag caatatgtct
      361 acgatgggga aagatgtgat caaacagcaa gacgctgact ttgatctcga ccggatggtc
      421 aatgtgtatc cgctgacgcc acggctggtt gagcaattac gcccgcggcc caatgtcgcg
      481 caaccgaata tgtcgctgga ccaggagatc gccagctatc agtatcgcgt cgggcctggc
      541 gatgtgctga atgtcaccgt ctgggatcac ccggaattga ccacgccagc aggccagtac
      601 cgtagctcaa gcgataccgg caactgggct cagccggacg gcaccatgtt ttatccctat
      661 attggcaagg ttagcgtcgt cggtaaaact ttgtcagaga ttcgcagcga tattaccggg
      721 cgtttagcga agtacatcgc agacccgcag gtggatgtca atatcgccgc tttccgctcg
      781 caaaaagcgt atatctccgg ccaggtgaat aaatccggtc agcaggccat tactaacgtc
      841 ccgctaaccg tcctggatgc gattaacgct gcgggcggcc tgaccgatat ggcggactgg
      901 cgcaacgtcg tgttgacgca caacggcaaa gaacagcgca tttcgctaca ggcgctgatg
      961 caaaatggcg atcttagtca gaaccgcttg ctctaccctg gcgacattct gtatgtgccg
     1021 cgcaatgacg atctgaaagt ctttgtcatg ggcgaagtga aaaaacagag caccctcaaa
     1081 atggatttca gcagcatgac gctcaccgaa gcattaggca atgcggaagg catcgatctg
     1141 accacctcca acgccagcgg catttttgtg attcgtccgt tgaaaggcga ggggggacgc
     1201 ggcggcaaga tcgccaatat ctaccagctt gatatgtctg acgccacgtc attggtgatg
     1261 gcgacggaat tccgacttca gccttacgat gtggtgtacg tcacgaccgc gccggttgct
     1321 cgctggaacc gtctgatcaa tcagttgctg ccgaccatta gcggtgtccg ttatatgacg
     1381 gatacggcca gcgacattca ttcctggtaa tcgttatgtt taacaaaatc ttagtggtct
     1441 gtgtggggaa tgtttgccgt tccccgacgg cggaacgttt gctaaagcgc tttcatcctt
     1501 cgctgacggt tgcgtctgcc ggattaggcg cgctggtcgg caaaggagcc gatcctgcgg
     1561 cggcgagcgt ggcgagcgcc cacgatctgt ctttggaaaa tcactgcgca aggcaaattt
     1621 ccgcgcgcct gtgccgggaa tatgacctga ttctgacgat ggagaaacgc cacatcgccg
     1681 ccctgtgcga cattgcgccg gaaatgcgca gcaaggtaat gctgtttggt cactgggaca
     1741 gcgagcgtga aataccagac ccgtatcgca aaagccgcga tgcgtttgag gcggtgtaca
     1801 cattactgga aaggtctgcc cgccagtggg cgcaggcact gaatgcagag cagggaaaac
     1861 catgacagaa aaagtaaaac aatctgcggc ggttacgggt agcgatgaaa tcgatatcgg
     1921 gcgtctggtc ggaacggtga ttgaagcgcg ttggtgggtg ttggggacga cggccatatt
     1981 tgcgctgtgc gcggtaattt atacgttctt cgccacgccc atctatagcg ccgatgcgct
     2041 ggtgcagatt gaacaaaacg ccggtaattc gctggtacag gatatcaaca gcgcattagc
     2101 gaataagccg ccggcttccg atgcggaaat tcagctcatt cgatcgcgcc tggtgctggg
     2161 gaagaccgtt gacgatctgg atctggatat tgccgtcacc aaaaacacct ttccgctgtt
     2221 cggcgccggg tgggagcggc tgatgggacg tcacaatgaa atggtgaaag tcacgacatt
     2281 cacccgacca gagacgatga gcggacagat cttcaccctc aaagtgctgg gcgacaaacg
     2341 ttatcagttg gtcagcgacg gcggatttag cgcgcagggc gttgtgggcc agccactcaa
     2401 taaagacggc gtgacgatgc gggtagaggc gattgacgcc cgtcctgata cggaatttac
     2461 ggtgagtaaa ttctcaacgc ttggcatgat taataacctg caaaataacc tcaccgtaac
     2521 ggaaaccggc aaagataccg gcgttctgaa cctgacgttc acgggagagg atcgcgacca
     2581 gatccgcgac attctcaaca gtattacccg taactatctg caacaggata ttgcgtggaa
     2641 atctgaagag gcggggaaga gcctggcgtt tctggcaaaa caactgccgg aagtccgcag
     2701 ccgtctggat gtggcggaaa acaagctaaa cgctttccgc caggataaag actcggtgga
     2761 tttaccgctg gaggcgaagg cggtgctcga ttcgatggtt aatatcgacg cccagttgaa
     2821 tgagttgacg tttaaagaag cggaaatttc caagctcttt accaaagcgc atccggctta
     2881 ccgcaccctg ctggaaaaac gtaaagggct ggaagataaa aaagccaaac tgaacgggcg
     2941 ggtgacggcg atgccgaaaa cccagcagga gattgtgcgt ttgacccgcg atgtggagtc
     3001 cggccagcag gtttatatgc aactgcttaa taaacagcag gagctgaaaa tcaccgaagc
     3061 cagcaccgtt ggcaacgtgc gcatcgttga cccggcgatt acccagccgg gcgtgctaaa
     3121 gccgaaaaag gcgttgatta ttctcggcag cattattctg ggattaatgt tatcgattgt
     3181 cggcgtgctg ctgcgctcgc tgtttaatcg cggtatcgaa agcccgcagg cgctggagga
     3241 gcacgggatc agcgtctatg ccagtattcc gctgtcggaa tggcaaaaag cgcgcgatag
     3301 cgtcaaaacc attaaaggga ttaagcgtta caagcagagc caactgctgg cggtgggcaa
     3361 tccgaccgat ctggcgattg aggcgattcg cagcctgcgc accagcctcc atttcgccat
     3421 gatgcaggcg caaaataatg tactcatgct cacaggcgtc agctcctcta tcggtaaaac
     3481 ctttgtttgc gccaacctgg cggccgtcat cagccagacg cataaacggg tattactgat
     3541 cgactgcgat atgcgcaagg gctacaccca tgaactgctc ggcaccaata acgtggacgg
     3601 cttatctgac attctggcgg gcaaaggcga gatagcctcc tgcgcgaaac ccacggcgat
     3661 cgctaatttt gatcttattc cgcgcggtca ggtaccgcct aatccatcgg aattgctgat
     3721 gagcgagcgc ttcggcgagc tgatcgcctg ggcaagcagc cgctacgacc tggtattaat
     3781 cgacacgccg ccgattctgg ccgtgacgga cgccgcgatt gtgggtcgtc acgtcgggac
     3841 gacgctgatg gtggcgcgtt atgccgtcaa caccttgaaa gaagtggaaa ccagtctgag
     3901 ccgttttgac cagaatggca ttcaggtcaa aggcgtcatt ctcaactcca ttttccgccg
     3961 ggcgacgggc taccaggatt atggctatta cgagtatgaa taccagtcag attccaaata
     4021 aaaaataagg cgtgccggat ggcgcggcct gtgactgtag gccggacaag cgtagcgcca
     4081 tgcggcaaaa ctatctgggg aataagcatg acaacagaca atccgctgat ctcaatttat
     4141 atgccaacct ggaacaggca gcagttggct atccgggcga ttaaatcagt actacgtcag
     4201 gactaccgtc actgggagat gatcatcgtg gatgattgct cctcgtctta tcagcagcta
     4261 caacaatttg ttgaggagct gaacgacccg cgcgttcgtt atactcataa cgccatgaat
     4321 accggcgcct gcgcggttcg caaccaggcc attatgcagg cgcaaggaca ctacattacc
     4381 gggattgatg atgacgatga atggacgccc aaccgtctga gcgtgtttct ggcccataaa
     4441 caccagttga ctacgcatgc ctttttgtat gccaacgact atgtgtgcga gggcgaggtc
     4501 tactctcagc ctgccagcct gccgctgtat ccgaaatccc cttattcgcg ccgcttgttc
     4561 tacaagcgca atattattgg caatcaggtt tttacctggg cctggcgttt taaagcgtgt
     4621 ttgttcgata ccgaactcaa ggcggcgcag gattacgaca tttttctgcg catggtggtg
     4681 gagtatggcg aaccgtggaa agttgaagag gcgacgcaaa ttttacatat caaccacggc
     4741 gagatgcaga ttacctcttc gccgaaaaag ttctccggct atttccattt ttatcgtaag
     4801 cacaaagata aattcgatcg cgccagcaaa aaataccagc tttttacgct gtaccaaatt
     4861 cgcaataagc gaatgacctg gcgcacgttg ctgacgttgc tctccgtgcg taatagcaaa
     4921 cgcctggcgg ccgggctgcg ggggcgataa cgatgctgga agacttacgc gcgaatagct
     4981 ggagcttacg cccctgttgc atggtgctgg cctaccgtat cgctcatttt tgttccgtct
     5041 ggcgcaaaaa gaatgtgctg aataatctgt gggccgcgcc ggtgctggtg ctgtatcgcg
     5101 tgatcacgga atgcctgttc gggtatgaaa tccaggccgc cgcgaccatt ggtcggcggt
     5161 tcactatcca tcatggttac gcggtagtga tcaacaaaca tgtcgtcgcc ggcgacgatt
     5221 ttaccattcg ccacggcgtc accattggca atcgcggcgc ggacagcctg gcttgtccgg
     5281 tgattggtca cggcgttgag ctgggggcga acgtcatcct gcttggcgat attactatcg
     5341 gtaatcacgt cacgattggc gcgggtagcg tggtgcttga cagtattccg gatcatgcgc
     5401 tggtggtggg agaaaaagca cgggtgaagg tcagcacatg aatattctgc aatttaatgt
     5461 acggctggcg gaaggcggtg cggcgggagt ggcgttagat cttcatctgc gggcgctgca
     5521 aaaagggctg acgtcgcatt ttgtttatgg ttatggcaaa ggcggaaaaa aaagcgtcag
     5581 tcaccaccgt tatccgcagg tgataaaaca gacgccgcgc ggcacggcaa tcgccaatat
     5641 cgcgctattt cgtttcctga atcgcgatct gtttggcaat ctcgacaatc tttaccgcac
     5701 ggttatccag acatccggcc cgctggtgct gcattttcat gttctccaca gttactggct
     5761 aaacctggcg gatatcgtga cgttttgcga aaaagtcaaa gcacaaaaac cggacgtcac
     5821 gctggtctgg acgctgcacg atcactggag cgttaccggg cgttgcgcct tcaccgacgg
     5881 ttgcgagggc tggaaaagcg gctgccaaaa atgtccgacc ctaagcaatt atccgccagt
     5941 cagggtggat cgggcgcacc agcttattga cggcaaacgt cagcgctttc gtgacatgct
     6001 gcggctgggc tgccagttta tttcgccgag ccagcatgtg gccgaggcct ttaacagcgt
     6061 ttatggcgcg ggactctgcc gggtgattaa caacggtatc gatctggcga ccgaggcgat
     6121 tctcgcgcaa ctatcacctg tgccgctgaa tccgggcaaa ccgcggatcg ccattgtggc
     6181 gcatgacttg cgttacgacg gcaaaactga ccagcgtctg gtacacgaca tgatggcgct
     6241 gggcgaaaaa attgaactgc ataccttcgg taaattttcg ccttttaccg gccaaaacgt
     6301 cgttaatcac ggttttgaaa ccgataagcg caaattaatg agcgcgctca atgagatgga
     6361 cgcgctggtc tttagctcgc gggtcgataa ctatccgctg atcttgtgtg aagcgctctc
     6421 gatcggcgta ccggtaatcg ccacccacag cgaggcggcg caggaggtgc tggcgaaatc
     6481 cggcggccag acttttgccg ctacagatgt actgcgcctg gcgcagcggc gtaagccaga
     6541 gattgctcag gcggtattcg gcgcaacgct ggacgccttt cgtatgcgta gccgcgtcgc
     6601 gtacagcggt caacagatgc tggaggagta tgtctcgttc tatcagaatc tgtagctatc
     6661 tgctgctgcc gctgatctac ctactggtca atgtcaagat tgcccaactg ggggaaagct
     6721 ttcccattac catcgtcact tttttaccgc tgttgctgct gttatttgtg gaacgcatta
     6781 gcgtaaaaaa attgatgatc gccttaggca tcggcgcggg gcttacggca tttaacttcc
     6841 tgttcggcca gtcgctgaat gccggtaaat atgtcacgtc cacgatgctg tttgtctata
     6901 ttgtggtcat tatcgggatg gtctggagta tccgattcaa aaccatttcc gcgcataacc
     6961 accgaaagat tttgcgtttt tttatctggt ggtgggtata gtggtcgcgc tcgccgcggt
     7021 tgagatggcg caaattatcc ttaccggcgg cagcagtatc atggaaggaa tttcgaaata
     7081 tctcatttac agtaatagct acgtactgaa cttcataaaa tttggcggta agcgtaccac
     7141 tgcgctttat tttgaaccgg catttttcgc tttggcacta atctcaattt ggctgagcat
     7201 caaacagttt ggtatcaaaa taccgaaaag cgatgctatg attctggcag ggataatatt
     7261 atcaggatca ttttcagggg taatgacctt tatcctgttt taccttctgg agtgggcgtt
     7321 ccaatatttg aataaggatg cgataaagaa aaaacttcca ctggcgctgg tatcattaac
     7381 cctgtttttg gttggggtaa ttattgcatt tccttatatc gcgacacgac ttggcgattt
     7441 agggacggaa ggattatctt cttattatcg tattgtgggc ccgttagtca tggtcggata
     7501 ttccttgacc catattgatg gtgtagtcag atttggctca ctttatgaat atgtcgcatc
     7561 attcggaatc tttaacggtg cggatgtcgg gaaaaccata gacaatggat tgtatctgct
     7621 gattatttat ttttcctggt tcgcagtgct aatgacgctg tggtatatgg ggaaagtttt
     7681 aaaaatggcg ctaaatgcgt ttggcgataa tcgcaatttt cgggtgcagc tctatctttt
     7741 tacgccggtg tcgctgtttt ttaccggttc aatatttagc ccggaatatg cttttttaat
     7801 cgtctgtccg ttcattttgc gcaaggcgtt aaaaatttca taacggggtg gttgcatgtt
     7861 tttaagcgtc gttaccgtcg cctttcgcaa ttacgaaggg gtggtaaaaa cctggcgctc
     7921 gctgcgcaat ctggcgcgcg atccgggcct gtcatttgaa tggatcgtag tggatggcgg
     7981 ttcggaggac ggcacgcgcg aatttctgca aaaacgtcac ggtgagttta acctgcgttt
     8041 tatcagtgaa aaggatcgcg gtatttatga tgccatgaac aaaggcattg ccttggcgca
     8101 ggggcgctat accctgtttc ttaattccgg tgatgcgttc catgatgatg ccgcgctgtt
     8161 tgtccgccaa ctggcgcggc aaaagggcga ggcgatgtat attggcgacg cgctgctgga
     8221 tttcggcggc gggcataaaa tacgccggaa agctaaaccc gggtattata tctaccatag
     8281 tttgccagcc agccatcagg cgatattttt cccgacggca gcgttaaaaa agtatcctta
     8341 tgatctgcaa tatcatgtct cttcagatta tgcgctggcg gcccgtctct ataaagcagg
     8401 ctatcctttt cggcgaatta acggactggt atctgaattt tcgatgggcg gcgtgtcaac
     8461 ctcgaataat ctggaattat gtcaggatgc aaaaaacgta cagcgaaaaa tattacgtgt
     8521 tccagggttt tgggcgcaat tatcctattt gttacgtctg aaaacgacgg gtaaaacaaa
     8581 agcgcggtat aacaaagtct aatcaccggg agttattatg caggatctta gcggctttac
     8641 ggtgccgaaa gggttccgcg gcgctaatgc gctaaaagta caattatggt gggcggtaca
     8701 ggcgacatta ttcgccggat cgccgcaaat attgtatcgc tggcgagcct ttttgctgcg
     8761 tctgtttggc gccaaaattg gaaaaaatgt ggttattcga ccgtcagtaa aaattaccta
     8821 tccgtggaaa ttaaccgtcg gcgattatgc ctggataggc gacgacgctg tgttatatac
     8881 gttgggtgaa attaatattg gcgcacatgc ggttatttca caaaaaggtt atttatgtac
     8941 cggtagccat gattatacca gcgcccattt cgatattaac gccgcgccga ttgttattgg
     9001 cgaaaaatgt tggctggcga ccgatgtttt tgtcgcgccc ggcgtgacga taggtcatgg
     9061 caccgtcgtc ggcgcgcgta gcagcgtatt taaatcatta ccggcaaatg cgatttgtcg
     9121 gggcaatccc gcagtggtaa cgcgccagcg cgttcagaaa gttactccct aacgggacta
     9181 tttgaggaaa tgaaaatgtc aaaagtcgct ctcattactg gcgtaaccgg acaggatggg
     9241 tcttacctgg cagaatttct gctggaaaaa gggtatgagg tgcatggtat caagcgtcgc
     9301 gcgtcatcgt ttaataccga gcgcgtggac catatttatc aggacccgca cagctgcaac
     9361 ccgaaatttc atctgcatta tggcgacctg accgacgcct caaacctgac ccgcatttta
     9421 caagaagtgc agccggatga ggtctacaac ctgggcgcga tgagccacgt ggcggtgtcg
     9481 tttgagtcgc cggaatatac cgccgatgtg gatgcgatgg gcactctgcg cctgctggag
     9541 gcgatccgct tcctcggtct tgaaaagaaa acgcgtttct accaggcctc cacctctgaa
     9601 ctgtacgggc tggtgcagga aatcccgcag aaagagacca cgccgttcta cccgcgttct
     9661 ccctatgcgg tggcgaaact gtacgcctac tggatcaccg tcaactaccg tgaatcctac
     9721 ggtatttacg cctgtaacgg cattctgttt aaccacgagt ctccgcgtcg tggcgaaacc
     9781 ttcgtcaccc gtaagatcac ccgcgccatc gccaatatcg cccagggact ggagtcctgc
     9841 ctgtatctcg gcaacatgga ctcgctgcgc gactggggcc atgcgaaaga ttacgtacgg
     9901 atgcagtgga tgatgttaca gcaggagcag ccggaagatt tcgtgattgc caccggcgtg
     9961 cagtattccg tacgccagtt tgtggagctg gcggcggcgc aactggggat aaaactgcgc
    10021 tttgaaggcg aaggcattaa tgagaaaggg atcgtggtat ccgttaccgg acacgatgcg
    10081 ccgggcgtga aaccgaggga tgtgattgtg gccgttgatc cgtgttattt ccgtccggcg
    10141 gaagtggaaa ccctgctggg cgatccgtcc aaagcgcatg agaaactggg ctggaaaccg
    10201 gaaattaccc tgtcggagat ggtctccgag atggtggcga acgatctgga ggccgcgaaa
    10261 aaacactcac tgctgaaatc tcacggttac gaggtggcca tcgcgctgga gtcctgagaa
    10321 tgaataagca acgaattttt gtggcgggcc atcgcgggat ggtgggctcc gccattgtac
    10381 ggcagcttgc gcagcgcggc gacgtggaac tggtgctgcg cacccgcgat gagctggatc
    10441 tgctcgacgg gcgcgcggta caggcgttct ttgccggagc gggtatcgac caggtttatc
    10501 tggcggcggc gaaagtgggc ggcattgttg ccaacaacac gtatccggcg gattttattt
    10561 atgaaaacat gatgatagag agcaacatta ttcacgccgc gcacctgcac aacgtgaaca
    10621 aactgctgtt tctcggttcg tcctgtatct atccgaaact ggcaaggcag ccgatggcgg
    10681 aaagcgagct gctgcagggg acgctggagc cgaccaacga gccgtatgcc atcgccaaga
    10741 tcgccgggat taaactgtgc gagtcctaca accggcagta cggtcgcgac taccgttcgg
    10801 tgatgccaac caacctgtac ggcccgcatg ataatttcca cccggacaat tcacatgtga
    10861 tcccggcgct gctgcgtcgc tttcatgagg ctgcgcagag ccacgcgccg gaggtggtgg
    10921 tgtggggcag cggcacgccg atgcgcgaat ttctgcacgt tgacgatatg gcggcggcca
    10981 gcattcacgt gatggagctg gcgcgcgaag tgtggcagga gaacaccgcc ccgatgctgt
    11041 cgcacattaa cgtcggcact ggcgtggact gcaccattcg cgagctggcg cagaccatcg
    11101 caaaggtggt gggttaccag ggccgggtgg tgttcgacgc cgcgaagccg gacggcacgc
    11161 cgcgtaaatt gctcgacgtc acgcgcctgc atcagcttgg ctggtatcac gaaatttcac
    11221 tggaggcagg gcttgccggt acttaccagt ggttccttga gaatcagcaa cggttccggg
    11281 ggtgacaatg tttttacgtc aggaagattt cgccgccgtg gtgcggacca cgcccctcat
    11341 ctccctcgat ttcatcgtgg aaaacggcca gggggaaatt ttgctgggcc agcgcctcaa
    11401 ccgtccggcg cagggctact ggtttgtgcc gggggggcgg gtgtgcaaag acgaaacgct
    11461 ggaggccgct tttgcacgcc tgacgcaggc ggaactgggc gtgcgtctgc cgctggcggc
    11521 agggacgttt tatggcgtct ggcagcactt ctatgacgac aacttttcca gtgaggattt
    11581 ttcaactcac tacatcgtgc tcggctttcg tctgcgcgtg gcggagagcg atttacgcct
    11641 gcctgatgcc cagcatggca gttaccgctg gctgacgccg gaacagcttc tggcaggcga
    11701 caatgttcat gagaacagtc gggcctactt ctctcctgac gcgccggcgg tgggcctatg
    11761 aagatcctgg tctatggcat taactattca ccggaactga ccggtatcgg caaatatacc
    11821 ggcgaaatgg tggcgtggat ggcgcgggaa ggccatgagg tgcgggttat tactgcgccg
    11881 ccgtactacc cgcagtggaa ggtcggtgag cgctattccg cctggcgcta tcgccgggaa
    11941 gagggcgagg ctaccgtctg gcgctgcccg ctgtatgtgc cgaaacagcc ctccacccta
    12001 aaacgactgc ttcatctggg gagctttgca ttgagcagtt ttttcccact gatggcgcag
    12061 cgtcgctgga agccggatcg gattatcggc gttgtaccga cgctcttttg tacgccggga
    12121 atgcgtctgc tggcgacact ctccggcgcg cgtaccgtac tgcatattca ggattacgaa
    12181 gtggacgcca tgctcggctt aggaatggcg ggaaaaggca agcgcggcag cgtagcgcgg
    12241 ttagcgacgg cctttgaacg cagcgcgctg cgtaacgttg ataatgtttc gaccatctct
    12301 cgctccatga tgaataaagc gcgggaaaag ggcgtcgcgg cggaaaaaat cctctttttt
    12361 ccaaactggt cggaagtggc gcgctttcag gacgttaatg acgctgacgt gacggctttg
    12421 cgtcagcagc ttggcttgcc agagggcaaa aaaatcgtgc tctattccgg caatatcggc
    12481 gaaaaacaag ggctggaaaa ggtgattgac gccgcagaac gattacgcga tcgaccgttg
    12541 atttttgcga ttgtcggcca ggggggcggc aaggcgcggc tggagaacat ggcccgcgaa
    12601 cgcggcctgc taaatattaa attcctcccg ctgcagcctt acgacgcctt acccgcgctg
    12661 ctgaaaatgg gcgactgcca tctggtggtg caaaagcgcg gcgcagcgga tgcggtactg
    12721 ccctccaagc tgactaacat tctggcggtc ggcggtaatg cggtgattac cgctgagccg
    12781 cacaccgaat taggacaact ttgcgcgcgc tatccgggca tcgccgtttg cgtggagccg
    12841 gagtcgaccg acgcgctggt cgacgggatt agccaggcgc tcgccatgcc gaaaaacaac
    12901 acgacggcac gtgaatacgc cgaacgcacg ctcaataaag agaacgtgct acgccaattt
    12961 attgcagata ttcggggatg ataatgcgtc agacaaaact ttacccggtt gtgatggccg
    13021 gtggctccgg tagccgattg tggccgcttt ctcgcgtgct ttatccaaaa cagtttttgt
    13081 gcctgaaagg cgatctcacc atgttgcaaa ccaccatttg ccgtctgaac ggcgtggagt
    13141 gcgaaagccc ggtggttatc tgcaacgaac agcaccgttt tatcgtcgcc gaacagctcc
    13201 gccagctcaa taagctgacg gagaacatta ttcttgagcc cgccgggcgc aataccgcgc
    13261 cggcgattgc gttggcggcg ctggcagcga cgcgccagca tacggactgc gatccgctga
    13321 tgctggtact ggcggcggat catgcgatcg ccaatgaaga ggccttccgc gacgcggtgc
    13381 gcggcgccat gccctatgcc gacgcgggca aactggtgac cttcggtatc gtgccggatc
    13441 tgccggaaac cggctatggc tatatccggc gcggtgatgt cgtgccgggc gcgacggatg
    13501 cggtggcttt tgaggtggcg cagttcgttg agaagccggg gctggaaacc gcccaggcct
    13561 acgtcgccag cggcgattac tactggaaca gcggcatgtt tctattccgc gccggacgct
    13621 atctggaaga gctgaaaaag ttccgccccg atattctggc cgcctgtgaa caggcgatgc
    13681 gcggcgtcga tccggatctt gacttcattc gcgtggatga agaggccttc ctcgcctgtc
    13741 cggaagagtc cattgactac gcggtgatgg agcggacggc ggacgcggtg gtgatgccaa
    13801 tggacgcggg ctggagcgat gtcggctcgt ggtcctcact gtgggaaatc agcgcccaca
    13861 ccccggaggg aaacgtccac cacggcgacg tcatcagtca taaaacggaa aacagctacg
    13921 tttacgccga atccggcctg gtgaccaccg tcggcgtgaa ggatctggtg gtggtgcaga
    13981 ccaaagacgc cgtgctgatt gccgatcgcc acgcggtgca ggacgtgaaa aaggtggtgg
    14041 agaagatcaa ggccgacgga cgccatgagc accacatgca ccgcgaggtt taccgtccgt
    14101 ggggcaaata cgactccatc gacgcgggcg agcgctatca ggtgaagcgc attaccgtta
    14161 agccggggga aggactgtcg gtgcagatgc accatcaccg tgccgagcac tgggtggtgg
    14221 tggcggggac cgccagagtc accatcaacg gcgaggttaa gctgctcggt gaaaacgagt
    14281 ccatctatat tccgctgggg gcgacccact gcctggaaaa tccgggaaaa ataccgctcg
    14341 atttaattga agtgcgttcc ggctcgtatc tcgaagagga cgacgtggtg cggttcgagg
    14401 accgttacgg gcgggtctga cgcctgcaat tatgcccggt aagcgcaacg cgccatccgg
    14461 caatgaataa caataacgat gttggccatt tgcggtcagg gctaactgtt gcctgaagaa
    14521 gggtaagcac atgacaaaat taacctgttt caaggcctac gacattcgcg gcaggctggg
    14581 cgaagagctc aatgaagata tcgcgtggcg gattggccgc gcctatggcg aatatttaaa
    14641 accgaaaacc atcgtgctgg gcggcgacgt gcgcctgacc agcgaggtgc tgaagatggc
    14701 gctggcaaaa gggttacagg acgcgggcgt cgacgtgctg gatatcggta tgtccggcac
    14761 cgaagagatt tacttcgcca ccttccacct cggcgtggac ggcggtattg aagtgaccgc
    14821 cagccataac ccgatggact acaacggtat gaagctggtg cgcgagggcg cccgcccgat
    14881 aagcggcgac accggtctgc gcgacgttca gcgcctggcg gaagcgggcg acttcccgcc
    14941 ggtcaacgac gccacgcgcg gcagctacag acaaatcagc atgcgcgacg cctacatcga
    15001 ccacctgctc ggctacatca gtgttaacaa tctcaccccg ctgaagctgg tgtttaacgc
    15061 cggcaacggc gcggcggggc cggtcattga cgccattgaa gcgcgcctga aggcgctggg
    15121 cgcgccggtg gagttcatca aaatccacaa caccccggac ggcaccttcc cgaaaggcat
    15181 tcccaacccg ttgctgccgg agtgtcgcga cgacacccgc aaggccgtta ttgaacacgg
    15241 ggcggacatg ggcatcgcct ttgacggcga cttcgaccgc tgcttcctgt tcgatgagaa
    15301 agggaagttt atcgaggggt actacatcgt cgggctgctg gcggaagcgt ttctggaaaa
    15361 acacccgggg gcgaagatta tccacgaccc gcgcctgacc tggaacaccg aggcagtggt
    15421 gacggcggcg ggcgggacgc cgatgatgtc aaaaaccggg cacgccttta tcaaggagcg
    15481 gatgcgtacg gaggatgcca tttatggcgg ggaaatgagc gcgcatcact atttccgtga
    15541 ttttgcctac tgcgacagcg ggatgatccc gtggctgctg gtggcggaac tggtatgcct
    15601 gaaggggcag tcgctgggtg aactggttcg cgaccggatg gcggcgttcc cggcgagcgg
    15661 ggaaatcaac agcagactgg cggagccggc ggcggccatc gcgcgggtgg aagcgcactt
    15721 cgcggaagag gcgcaggcag tggaccgcac ggacggcctc agcatgtcgt tcgccgactg
    15781 gcgtttcaac ctgcgctcgt cgaacaccga accggtggtg cgcctgaatg tggaatcacg
    15841 cggcgatatt ccgctgatgg aagcgcgaac acgcactctg ctggcgctgc tgaatcagta
    15901 acgtcagatc tccccttacc gcctgcgggt aaggggccaa tcacaggaac aacgatgaca
    15961 aatctaaaaa agcgcgaacg agccaaaacc aatgcatcgt taatctctat ggtgcaacgc
    16021 ttttcagata tcaccatcat gtttggcggg ctgtggttca tctgtgaagt cagtggactg
    16081 ccattcctgt acatgcacct gttggtggcg ctgattacgc tggttgtttt tcaaatgctg
    16141 ggcgggatga ccgattttta tcgctcctgg cgcggcgtca aaatgtcgac agagttaacg
    16201 ctgttactgc aaaactggac gctgagcctg atcttcagcg ccggtctggt ggcgtttaat
    16261 gatgactttg acaaccgcct cgccacctgg ttggcctggt atgcgctgtc cagcctgggc
    16321 ttagtgttat gccgttcatt tattcgtttc ggcgcgggct ggctacgcaa tcgtggttat
    16381 aacactcgcc ggggcgccgt cgccggggat ttgcctgcgg gccaggcgtt gctggatagc
    16441 ttccgtaatg agccgtggct gggttttgag gtggtgggcg tctatcacga tcctaaaccg
    16501 ggcggcgtct ctgctgactg ggccgggaac ttcgaacagt taattgacga tgcgaaagcc
    16561 tcgcgaattc acaatgttta tatcgccatg tcaatgagcg acggcgccat ggtgaaaaaa
    16621 ctggtgcgcg agctggccga caccacctgc tcggtgatcc ttattcccga tgtgttcacc
    16681 tttaatattc tccactcgcg cgtggaggag atgagcggcg ttccggtcgt tccgctgtat
    16741 gacacgccgc tatcagggat taaccgtctg cttaaacggg cagaagatat cgtgctggcg
    16801 tcgctgattc tgctgctcat ctcaccggta ctgtgctgca ttgcgccggc ggtcaaattg
    16861 agctcgcccg ggccggtgat tttccgtcag acgcgctacg ggatggacgg caagccgagc
    16921 aaagtctgga ggttccgctc aatgaaggtg atggagaacg ataaggtcgt tacccaggcg
    16981 acgcaaaacg atccgcgcgt cacccgggta ggtaactttt tgcgtcgtac ctcgctggat
    17041 gaattaccgc agtttatcaa cgtattaacc ggcgggatgt ctatcgtcgg tcctcgcccg
    17101 cacgcggtgg cgcataacga acagtatcgt cagttgattg aaggttacat gctacgccac
    17161 aagatgaagc cgggcatcac cggctgggcg caaattaatg gctggcgcgg tgagaccgat
    17221 acgctggaga aaatggaaaa acgcgtggaa ttcgacctgg aatacatccg cgaatggagt
    17281 atttggttcg atatcaaaat cgtttttctg acgattttta aagggtttgt taataaagcg
    17341 gcgtattaag aacctgaccc acaaggctat tttacttgcc atattgcacc agggcagtgc
    17401 tcaatctggc tgcgccaatg acgccttgtg aacaggttct ggagaaaaga atgagtttac
    17461 gacaaaaaac gatcagcggc gttaaatggt cggctatcgc cacgatagtg attatcggtc
    17521 tggggttaat tcagatgacg gtgctggcgc ggatcatcga caaccaccag tttggcctgt
    17581 tgaccgtatc gctggtgatt atcgcgctgg ccgacacgat ttcggacttt ggcatcgcga
    17641 actcgattat ccagcgtaaa acgattgggc atctggagct gaccacgctt tactggctaa
    17701 acgttgggct tgggattgtg gtatttgcgg tggtcttttg gctgagcgat gcgattgccc
    17761 atgttttgca taacccggat ctcgcgccgt taatcaaaac gttgtcgctg gcgttcatcg
    17821 tgatccctca cgggcagcag ttccgcgcgc tgatgcaaaa agagctggag ttcaataaga
    17881 tcggcatgat cgaaacgacc tccgtgctgg cggggttcac ctttacggtg attagcgccc
    17941 attactggcc gctggcgtta accgcgattc tcggctatct ggtgaacagc gcggtgcgaa
    18001 cgctgctgtt tggttacttt ggccgcaaga tttaccgtcc ggggctgcat ttttcgctgg
    18061 catcggtgtc cacgaacctg cgttttggcg cgtggctgac ggcggacagt atcgtcaatt
    18121 acatcaacac gaatttatcg acgctggtac tggcgagaat tctcggcgca agcgtcgccg
    18181 ggggatataa cctcgcgtac aacgtggctg ttgtgccgcc ggcgaagctt aaccccatca
    18241 ttactcgcgt gctatttccg gcattcgcca aaatccagga cgataccgag aagctgcgcg
    18301 tcaacttcta taagttgctt tccgtggtgg gaattatcaa ttttcccgcg ctgttgggcc
    18361 tgatggtagt ggcgaacaat tttgtgccgt tagtgtttgg tgagaagtgg aacagcatta
    18421 tcccgatcct gaaattgctg tgcgttgtgg ggctgctgcg ctcagtcggc aacccgattg
    18481 gttcgctgct gatggcgaaa gcgcgcgtgg atatcagctt taagttcaac gtctttaaaa
    18541 cgtttctgtt tatcccggca attctcattg gcggccatct ggcgggggcg attggcgtga
    18601 cgctggggtt cctggtggtg caaatcatca acaccattct gagctatttc gtgatgatta
    18661 agccggtact cggctccagc taccgtcagt atattctcag cctgtggcta ccgttttatc
    18721 tctcattgcc cacatttatt accagctacg gcgcaggaaa gctagtcgac ggctatttac
    18781 cgttgtcagg ggtattcgcg ctacaggttg tggtcggtat tttgagtttt attttaatga
    18841 ttattttttc acgcaatgcg ctggtgatgg aaattaaaaa tcagcttgtt ggcagtgaaa
    18901 aaatgaaaaa gttattacgt gtcggatgac gaggatataa gaggctattt atgaaattat
    18961 taattttagg caaccacaca tgcggcaacc gtggtgatag cgccattatg cgcggtttgc
    19021 ttgatgccat ccgtcaacag gcgccagagg cggagatgga tgtgatgagc cgtttcccgg
    19081 tgagttcctc ctggttgcag gggcgaccga ttattgccga cccgctgtat caattaagcc
    19141 agaaacagca ggcggcggca gggcttaacg gtcgggtgaa aaagtattac gccgtcgttt
    19201 tcagcataaa attttattgt ctaaagtcgc ccaggaagga tcgctgcgta attttgctat
    19261 cgcgccggaa tttgccgaat tcgcgcaatt tattgcgcag tatgacgccg tcattcaggt
    19321 gggcggttca aactatgtcg acttatacgg tttgactcac tttgaatatc cgctgtgcgc
    19381 gtttatggcg aacaaaccaa tttatatggt gggacatagc gtcggccctt tccagaaccc
    19441 tgactttaac tagctcgcca attatgtttt gggcgcacca gtgcgctgat cctgcgtgaa
    19501 accgtcagcc gcgatctgat gaccgccgcg cagatcgata cccgaaaagt agagcagggg
    19561 gtggataccg cctggttagt cgaacgccgt cacgacgagt ttgtcgccag ttatgctgtg
    19621 cagcactggc tggacgtcac cgcgcgccgc aaaaccgtcg cgattacgtt gcgcgatctg
    19681 gagccgtttg ataaacgcct gggcaccact cagcaggcct atgagcaggc atttgcccag
    19741 gtcgtgaatc gcctgattgc ggacggttat caggtactgg cgctgtcgac ctgcaccagt
    19801 atcgatcgct ataaccgcga tgaccggatg gttgcgttac ggatggcgaa gtatgtaaac
    19861 gactcagagc atttccatat cgcgatggac gaactcaatg acgtggaaat cggaaagatc
    19921 ctcgcatcct gcgtactgac catcgggacg cgcctgcatt ccgccattat ctccatgaat
    19981 tttggcacgc ccgctatcgc cattaattat gaacataaat ccgccgggat tatgcagcag
    20041 ctaggcctgg cggaattggc catcgatatc cgtcacttgc tgaacggttc attacaaagc
    20101 gtggtggccg atacgctcaa tcaattgcct gcgctaaagg caaaagtggc taacgccgtc
    20161 accgaggagc gggcgaaagg gttcacgatg atcaaatctg ctctcgacag aattcgggag
    20221 gcgcaatgaa agtcagcttt tttctgctga aatttccact ctcatcggaa acctttgtgc
    20281 tgaatcagat tactgcgttt attgatatgg gccatgaggt ggagattgtc gcgttacaaa
    20341 aaggcgatac ccaacatact cacgccgcct gggagaagta tggcctggcg gcgaaaaccc
    20401 gctggttaca ggatgagccc cagggacggc tggcgaagct gcgctaccgg gcatgtaaaa
    20461 cgctgccggg gctgcatcgg gcggcgacct ggaaagcgct caattttacc cgctacggcg
    20521 atgaatcacg caatttgatc ctttccgcga tttgcgcgca ggcgggccaa ccttttgtgg
    20581 cggatgtgtt catcgcgcac tttggtccgg cgggcgtgac ggcggccaaa ctgcgcgaac
    20641 tgggcgtgct tcgcggcaaa atcgagacta ttttccacgg aattgatatt tccagtcgcg
    20701 aggtgctcag tcattacacg ccggagtatc agcagttgtt tcgtcgtggc gatctgatgc
    20761 tgcccatcag cgatctgtgg gccggtcgcc tgaaaagtat gggctgtccg ccggaaaaga
    20821 ttgccgtttc gcgcatgggc gtcgacatga cgcgtttttc ccatcgtccg gtgaaagcgc
    20881 cagggatgcc gctggagatg atttccgtcg cgcgcctgac cgagaaaaaa ggcctgcatg
    20941 tggcgattga agcctgtcgg caactgaaag cgcagggcgt ggcgtttcgc taccgcattc
    21001 tggggattgg cccgtgggaa cgtcggctgc gcacgctcat tgagcagtat cagttagagg
    21061 atgtcattga gatgccgggt tttaaaccga gccatgaagt gaaggcgatg ctggatgacg
    21121 ccgatgtttt tttgctgccg tcgattaccg gtacggatgg cgatatggaa ggtattccgg
    21181 tagcgctgat ggagacgatg gcggtgggga ttcccgtggt gtctaccgtg catagcggta
    21241 ttccggaact ggtggaggcc ggcaaatccg gctggctggt accggaaaac gatgcgcagg
    21301 cgctggcggc ccgactcgct gagttcagcc ggattgacca cgatacgctg gggtcggtga
    21361 tcatgcgcgc tcgtgaaaaa gtggcgcaag attttaatca gcaggcgatt aatcgccagt
    21421 tagccagcct gctacaaacc atataaacga ggtggtatgc ccgcgactaa attctcccga
    21481 cgtaccctcc tgacggcagg ttccgcgctt gctgttcttc cttttctgcg cgccttgccg
    21541 gtacaggcgc gtgaacctcg ccagaccgtc gatattaagg attatccggc ggatgacggt
    21601 atcgcctcgt tcaaacaggc cttcgccgac gggcagactg tggtcgtgcc gtcaggatgg
    21661 gtgtgtgaaa atatcaatgc ggcgataacg attccggcgg gaaaaacgct gcggatacag
    21721 ggcgcggtgc gtgggaatgg ccggggacgg tttattttgc tggacgggtg tcaggtggtg
    21781 ggggagcagg gcggcagtct gcacaatgtg acgctggatg ttcgcgggtc ggactgtgtg
    21841 attaaaggcg tgacgatgag cggctttggc cccgtcgcgc aaattttcat cggcggtaag
    21901 gaaccgcagg tgatgcgtaa tctcattatc gatgacatca ccgttaccca cgccaactac
    21961 gccattctcc gccagggatt tcataaccaa atggacggcg cgcggattac gcatagtcgc
    22021 tttagcgatt tgcaggggga cgccattgag tggaatgtcg cgattcatga ccgcgacatc
    22081 ctgatttccg atcatgtcat cgaacgcatt gattgtacca atggcaaaat caactggggg
    22141 atcggcatcg ggctggcggg tagcgcctat gacaatagtt atcctgaaga ccaggcagta
    22201 aaaaactttg tggtggccaa tattaccgga tctgattgcc gacaactggt acacgtagaa
    22261 aatggcaaac atttcgtcat tcgcaatgtc aaagccaaaa acatcacgcc cgatttcagt
    22321 aaaaatgcgg gtattgataa cgcaacgatc gccatttatg gctgtgataa tttcgtcatt
    22381 gataatattg atatgacgaa tagtgccggg atgctcatcg gctatggcgt cgttaaagga
    22441 aaatacctgt caattccgca aaactttaaa ttaaacgcta ttcggttgga taatcgccag
    22501 gttgcttata aattacgcgg cattcaaatt tcctccggta acgccccctc atttgttgcc
    22561 atcaccaatg tacggatgac gcgtgctacg ctggaactgc ataatcaacc gcagcacctc
    22621 tttttgcgta atatcaacgt gatgcaaact tcagcgattg gcccggcgtt aaaaatgcat
    22681 tttgatttgc gtaaagatgt ccgtggtcaa tttatggccc gccaggacac gctgctttcc
    22741 ctcgctaatg ttcatgccat caatgaaaac gggcagagtt ccgtggatat cgacaggatt
    22801 aatcaccaaa ccgtgaatgt cgaagcagtg aatttttcgc tgccgaagcg gggagggtaa
    22861 gtaccgctat ttttacgaaa attcctggga aaaagttgtt catacttaat gttatggtgc
    22921 cgactaagac gtaatgtaga gcgtgccatc attatccctg gcagcagagt aattcatgct
    22981 ggcgaaaaca agctaaagag ctataattca gcaaccattt tacaggtgga agaaacaatg
    23041 atgaatttga aagcagttat accggtagcg ggtttgggta tgcatatgtt gcctgccacc
    23101 aaggcaatcc caaaagagat gctaccgatc gtcgacaaac cgatgattca gtacattgtc
    23161 gatgagattg tggctgcagg gatcaaagaa atcgtgctgg tgactcacgc gtctaaaaat
    23221 gccgttgaga accacttcga cacctcttat gaacttgaat cgcttcttga gcagcgcgtt
    23281 aagcgtcagc ttctggcgga agtgcaatct atctgcccac cgggcgtgac gattatgaac
    23341 gttcgccagg cgcagccgtt aggactgggg cactctattc tgtgcgcgcg tccggttgtg
    23401 ggcgataacc ctttcattgt ggtactcccg gatattatta ttgatgatgc taccgccgat
    23461 ccgctgcgct ataaccttgc ggcgatggtg gcgcgtttca atgaaacggg tcgcagccag
    23521 gtgctggcaa agcgcatgaa aggtgattta tcggagtatt ccgttatcca gacgaaagaa
    23581 cctctggata atgaaggcaa agtcagccgg attgtggagt ttatcgaaaa accggatcag
    23641 ccgcagacgc tggattccga tttgatggcg gtaggccgtt atgtgctttc agccgacatc
    23701 tgggcggaac tggaaagaac cgaaccgggc gcctggggcc gcatccagct taccgatgcg
    23761 attgctgaac tggcgaaaaa acagtcggtt gacgcgatgc taatgacggg cgacagctat
    23821 gactgcggta aaaaaatggg ctacatgcag gcatttgtga agtacgggct gcgcaacctg
    23881 aaagaaggag cgaagttccg taagagcata gagcagcttc tgcatgaata agtattaaca
    23941 accgtgataa atggttggtg ataaacataa taacggcagt gaacattcga agcggcaagt
    24001 tggctgaaac gagtgttgac tgccgtttta gttttgtata aagggcttaa gtaacaaggg
    24061 gttatctgga gcattttaat gctgatttta taagattaat ccttgtttcc ggatgcaatt
    24121 aataagacaa ttagcgttta agttttagtg agctttgccc tgctgggcga ggtttgtaac
    24181 aagtcgatat gtacgcagtg cact
//
LOCUS       DAJVBX010000050        23677 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.050, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000050 DAJVBX010000000
VERSION     DAJVBX010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 23677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23677
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.050"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..645)
                     /gene="pphB"
                     /locus_tag="OPV72_001734"
     CDS             complement(<1..645)
                     /gene="pphB"
                     /locus_tag="OPV72_001734"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-serine/threonine phosphatase"
                     /protein_id="HCR9914065.1"
                     /translation="MELIRYADINSVLYRHIWVVGDIHGCYSLLLTRLAQLNFSPDTD
                     LLISTGDNIDRGKENLETLRLLNTSWFISVVGNHEAMALDAFETQDGNFWYVNGGYWY
                     DSVTQKDRQEATELLLTFKQRPHIIEVKTSSKKYVIAHADYPDDSYDYGKQVDIDSVL
                     WSRDRLLSSLQGNIHPIRGADTFIFGHMIVDYTTTFANQIYIDTGSFCSGNLSFF"
     gene            872..1293
                     /locus_tag="OPV72_001735"
                     /pseudo
     CDS             872..1293
                     /locus_tag="OPV72_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_025243904.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            complement(1366..1893)
                     /locus_tag="OPV72_001736"
     CDS             complement(1366..1893)
                     /locus_tag="OPV72_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCR9914066.1"
                     /translation="MMFTDWHEAAIGKTHNRMNFDCGDADLNQFLQRHARQNHEKGTT
                     KTYVALDNSDVTRIHGFYSVSPASLIYAQVPGAISKGLGRYDVPVFRLGRLAVDKSMQ
                     GQGLGAQLLLSAGKRCIQAALQVGGVALLIDAKNKQVCDWYKGFGAVPLNDQPLSLLL
                     SFKTLYAALSASGRL"
     gene            complement(1890..2180)
                     /locus_tag="OPV72_001737"
     CDS             complement(1890..2180)
                     /locus_tag="OPV72_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1778 domain-containing protein"
                     /protein_id="HCR9914067.1"
                     /translation="MKTMPQIAIESNERLSLRVSTDAKKLIVRAAAIQQTNLTDFVVS
                     NVLPVAQKIVDAAERVYLTERDTQMIMEILDNPPAPNEKLLAAAFALPDMKK"
     gene            complement(2450..2650)
                     /locus_tag="OPV72_001738"
                     /pseudo
     CDS             complement(2450..2650)
                     /locus_tag="OPV72_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477168.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(3054..3497)
                     /gene="invH"
                     /locus_tag="OPV72_001739"
     CDS             complement(3054..3497)
                     /gene="invH"
                     /locus_tag="OPV72_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system invasion
                     lipoprotein InvH"
                     /protein_id="HCR9914068.1"
                     /translation="MKKFYSCLPVFLLIGCAQVPLPSSVSKPVQQPGAQKEQLANANS
                     IDECQSLPYVPSDLAKNKSLSNQNADNSASKNSAISSSIFCEKYKQTKEQALTFFQEH
                     PQYMRSKEDEEQLMTEFKKVLLEPGSKNLSIYQTLLAAHERLQAL"
     gene            3953..4603
                     /gene="invF"
                     /locus_tag="OPV72_001740"
     CDS             3953..4603
                     /gene="invF"
                     /locus_tag="OPV72_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system transcriptional
                     activator InvF"
                     /protein_id="HCR9914069.1"
                     /translation="MSFSESRHNENCLIQEGALLFCEQAVVAPVSGDLVFRSLKIEVL
                     SKLLAFIDGAGLVDTTYAESDKWVLLSPEFRAIWQDRKRCEYWFLQQIITPSPAFNKV
                     LALLRKSESYWLVGYLLAQSTSGNTMRMLGEDYGVSYTHFRRLCSRALGGKAKSELRN
                     WRMAQSLLNSVEGHENITQLAVNHGYSSPSHFSSEIKELIGVSPRKLSNIIQLADK"
     gene            4600..6288
                     /gene="invG"
                     /locus_tag="OPV72_001741"
     CDS             4600..6288
                     /gene="invG"
                     /locus_tag="OPV72_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system outer membrane ring
                     protein InvG"
                     /protein_id="HCR9914070.1"
                     /translation="MKTHILLARVLACAALVLVAPGYSSEKIPVTGSGFVAKDDSLRT
                     FFDAMALQLKEPVIVSKMAARKKITGNFEFHDPNALLEKLSLQLGLIWYFDGQAIYIY
                     DASEMRNAVVSLRNVSLNEFNNFLKRSGLYNKNYPLRGDNRKGTFYVSGPPVYVDMVV
                     NAATMMDKQNDGIELGRQKIGVMRLNNTFVGDRTYNLRDQKMVIPGIATAIERLLQGE
                     EQPLGNIVSSEPPAMPAFSANGEKGKAANYAGGMSLQEALKQNAAAGNIKIVAYPDTN
                     SLLVKGTAGQVHFIEMLVKALDVAKRHVELSLWIVDLNKSDLERLGTSWSGSITIGDK
                     LGVSLNQSSISTLDGSRFIAAVNALEEKKQATVVSRPVLLTQENVPAIFDNNRTFYTK
                     LIGERNVALEHVTYGTMIRVLPRFSADGQIEMSLDIEDGNDKTPQSDTTTSVDALPEV
                     GRTLISTIARVPHGKSLLVGGYTRDANTDTVQSIPVLGKLPLIGSLFRYSSKNKSNVV
                     RVFMIEPKEIVDPLTPDASESVNNILKQSGAWSGDDKLQKWVRVYLDRGQEVIK"
     gene            6285..7403
                     /gene="invE"
                     /locus_tag="OPV72_001742"
     CDS             6285..7403
                     /gene="invE"
                     /locus_tag="OPV72_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system gatekeeper InvE"
                     /protein_id="HCR9914071.1"
                     /translation="MIPGSTSGISFSRILSRQASHQDATQHTDAQQAEIQQAAEDSSP
                     GAEVQKFVQSTDEMSAALAQFRNRRDYEKKSSNLSNSFERVLEDEALPKAKQILKLIS
                     VHGGALEDFLRQARSLFPDPSDLVLVLRELLRRKDLEEIVRKKLESLLKHVEEQTDPK
                     TLKAGINCALKARLFGKTLSLKPGLLRASYRQFIQSESHEVEIYSDWIASYGYQRRLV
                     VLDFIEGSLLTDIDANDASCSRLEFGQLLRRLTQLKMLRSADLLFVSTLLSYSFTKAF
                     NAEESSWLLLMLSLLQQPHEVDSLLADIIGLNALLLSHKEHASFLQIFYQVCKAIPSS
                     LFYEEYWQEELLMALRSMTDIAYKHEMAEQRRTIEKLS"
     gene            7428..9485
                     /gene="invA"
                     /locus_tag="OPV72_001743"
     CDS             7428..9485
                     /gene="invA"
                     /locus_tag="OPV72_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system export apparatus
                     protein InvA"
                     /protein_id="HCR9914072.1"
                     /translation="MLLSLLNSARLRPELLILVLMVMIISMFVIPLPTYLVDFLIALN
                     IVLAILVFMGSFYIDRILSFSTFPAVLLITTLFRLALSISTSRLILIEADAGEIIATF
                     GQFVIGDSLAVGFVVFSIVTVVQFIVITKGSERVAEVAARFSLDGMPGKQMSIDADLK
                     AGIIDADAARERRSVLERESQLYGSFDGAMKFIKGDAIAGIIIIFVNFIGGISVGMTR
                     HGMDLSSALSTYTMLTIGDGLVAQIPALLIAISAGFIVTRVNGDSDNMGRNIMTQLLN
                     NPFVLVVTAILTISMGTLPGFPLPVFVILSVVLSVLFYFKFREAKRSAAKPKTSKGEQ
                     PLSIEEKEGSSLGLIGDLDKVSTETVPLILLVPKSRREDLEKAQLAERLRSQFFIDYG
                     VRLPEVLLRDGEGLDDNSIVLLINEIRVEQFTVYFDLMRVVNYSDEVVSFGINPTIHQ
                     QGSSQYFWVTHEEGEKLRELGYVLRNALDELYHCLAVTLARNVNEYFGIQETKHMLDQ
                     LEAKFPDLLKEVLRHATVQRISEVLQRLLSERVSVRNMKLIMEALALWAPREKDVINL
                     VEHIRGAMARYICHKFANGGELRAVMVSAEVEDVIRKGIRQTSGSTFLSLDPEASANL
                     MDLITLKLDDLLIAHKDLVLLTSVDVRRFIKKMIEGRFPDLEVLSFGEIADSKSVNVI
                     KTI"
     gene            9509..9916
                     /gene="spaK"
                     /locus_tag="OPV72_001744"
     CDS             9509..9916
                     /gene="spaK"
                     /locus_tag="OPV72_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system chaperone SpaK"
                     /protein_id="HCR9914073.1"
                     /translation="MQHLDIAELVRSALEVSGCDPSLIGGIDSHSTIVLDLFALPSIC
                     ISVKDDDVWIWAQLGADSMVVLQQRAYEILMTIMEGCHFARGGQLLLGEQNGELTLKA
                     LVHPDFLSDGEKFSTALNGFYNYLEVFSRSLMR"
     gene            9913..11208
                     /gene="invC"
                     /locus_tag="OPV72_001745"
     CDS             9913..11208
                     /gene="invC"
                     /locus_tag="OPV72_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SctN family type III secretion system ATPase
                     InvC"
                     /protein_id="HCR9914074.1"
                     /translation="MKTPRLLQYLAYPQKITGPIIEAELRDVAIGELCEIRRGWHQKQ
                     VVARAQVVGLQRERTVLSLIGNAQGLSRDVVLYPTGRALSAWVGYSVLGAVLDPTGKI
                     VERFTPEVAPISEERVIDVAPPSYASRVGVREPLITGVRAIDGLLTCGVGQRMGIFAS
                     AGCGKTMLMHMLIEQTEADVFVIGLIGERGREVTEFVDMLRASHKKEKCVLVFATSDF
                     PSVDRCNAAQLATTVAEYFRDQGKRVVLFIDSMTRYARALRDVALASGERPARRGYPA
                     SVFDNLPRLLERPGATSEGSITAFYTVLLESEEEADPMADEIRSILDGHLYLSRKLAG
                     QGHYPAIDVLKSVSRVFGQVTTPTHAEQASAVRKLMTRLEELQLFIDLGEYRPGENID
                     NDRAMQMRDSLKAWLCQPVAQYSSFDDTLSGMNAFADQN"
     gene            11186..11629
                     /gene="spaM"
                     /locus_tag="OPV72_001746"
     CDS             11186..11629
                     /gene="spaM"
                     /locus_tag="OPV72_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system protein SpaM"
                     /protein_id="HCR9914075.1"
                     /translation="MHSLTRIKVLQRRCTVFHSQCESILLRYQDEDRGLQAEEEAILE
                     QIAGLKLLLDTLRAENRQLSREEIYTLLRKQSIVRRQIKDLELQIIQIQEKRSELEKK
                     REEFQKKSKYWLRKEGNYQRWIIRQKRHYIQREIQQEEAESEEII"
     gene            11629..12639
                     /gene="spaN"
                     /locus_tag="OPV72_001747"
     CDS             11629..12639
                     /gene="spaN"
                     /locus_tag="OPV72_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system protein SpaN"
                     /protein_id="HCR9914076.1"
                     /translation="MGDVSAVSSSGNILLPQQDEVGGLSEALKKTVEKHKTEYSGDKK
                     DRDYGDAFVMHKETALPVLLAAWRHCAPAKSEHHNGNVSGLHHNGKGELRIAEKLLKV
                     TAEKSVGLISAEAKVDKSAALLSPKNRPLESVSGKKLSADLKAVESVSEVTDNATGIS
                     DDNIKALPGDNKAIAGEGVRKEGAPLARDVAPARMAAANTGKPDDKDHKKVKDVSQLP
                     LQPTTIADLSQLTGGDEKMPLAAQSKPMMTIFPTADGVKGEDSSLTYRFQRWGNDYSV
                     NIQARQAGEFSLIPSNTQVEHRLHDQWQNGNPQRWHLTRDDQQNPQQQQHRQQSGEED
                     DA"
     gene            12639..13550
                     /gene="spaO"
                     /locus_tag="OPV72_001748"
     CDS             12639..13550
                     /gene="spaO"
                     /locus_tag="OPV72_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system protein SpaO"
                     /protein_id="HCR9914077.1"
                     /translation="MSLRVRQIDRREWLLAQTATECQRHGREATLEYPTRQGMWVRLS
                     DAEKRWSAWIKPGGWLEHVSPALAGAAVSAGAEHLVVPWLAATERPFELPVPHLSCRR
                     LCVENPVPGSALPEGKLLHIMSDRGGLWFEHLPELPAVGGGRPKMLRWPLRFVIGSSD
                     TQRSLLGRIGIGDVLLIRTSRAEVYCYAKKLGHFNRVEGGIIVETLDIQHIEEENNTT
                     ETAETLPGLNQLPVKLEFVLYRKNVTLAELEAMGQQQLLSLPTNVELNVEIMANGVLL
                     GNGELVQMNDTLGVEIHEWLSESGNGE"
     gene            13540..14214
                     /gene="spaP"
                     /locus_tag="OPV72_001749"
     CDS             13540..14214
                     /gene="spaP"
                     /locus_tag="OPV72_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system export apparatus
                     protein SpaP"
                     /protein_id="HCR9914078.1"
                     /translation="MGNDISLIALLAFSTLLPFIIASGTCFVKFSIVFVMVRNALGLQ
                     QIPSNMTLNSVALLLSMFVMWPIMHDAYVYFEDEDVTFNDISSLSKHVDEGLDGYRDY
                     LIKYSDRELVQFFENAQLKRQYGEETETVKRDKDEIEKPSIFALLPAYALSEIKSAFK
                     IGFYLYLPFVVVDLVVSSVLLALGMMMMSPVTISTPIKLVLFVALDGWTLLSKGLILQ
                     YMDIAT"
     gene            14240..14500
                     /gene="spaQ"
                     /locus_tag="OPV72_001750"
     CDS             14240..14500
                     /gene="spaQ"
                     /locus_tag="OPV72_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system export apparatus
                     protein SpaQ"
                     /protein_id="HCR9914079.1"
                     /translation="MDDLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQE
                     QTLPFGIKLLGVCLCLFLLSGWYGEVLLSYGRQVIFLALAKG"
     gene            14504..15295
                     /gene="spaR"
                     /locus_tag="OPV72_001751"
     CDS             14504..15295
                     /gene="spaR"
                     /locus_tag="OPV72_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system export apparatus
                     protein SpaR"
                     /protein_id="HCR9914080.1"
                     /translation="MLYALYFEIHHLVASAALGFARVAPIFFFLPFLNSGVLSGAPRN
                     AIIILVALGVWPHALNEAPPFLSVAMIPLVLQEAAVGVMLGCLLSWPFWVMHALGCII
                     DNQRGATLSSSIDPANGIDTSEMANFLNMFAAVVYLQNGGLVTMVDVLNKSYQLCDPM
                     NECTPSLPPLLTFINQVAQNALVLASPVVLVLLLSEVFLGLLSRFAPQMNAFAISLTV
                     KSGIAVLIMLLYFSPVLPDNVPRLSFQATGLSSWFYERGATHVLE"
     gene            15282..16352
                     /gene="spaS"
                     /locus_tag="OPV72_001752"
     CDS             15282..16352
                     /gene="spaS"
                     /locus_tag="OPV72_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system export apparatus
                     protein SpaS"
                     /protein_id="HCR9914081.1"
                     /translation="MSSNKTEKPTKKRLEDSAKKGQSFKSKDLIIACLTLGGIAYLVS
                     YGSFNEFMGIIKIIIADNFDQSMADYSLAVFGIGLKYLIPFMLLCLVCSALPALLQAG
                     FVLATEALKPNLSALNPVEGAKKLFSMRTVKDTVKTLLYLSSFVVAAIICWKKYKVEI
                     FSQLNGNVVDIAVIWRELLLALVLTCLACALIVLLLDAIAEYFLTMKDMKMDKEEVKR
                     EMKEQEGNPEVKSKRREVHMEILSEQVKSDIENSRLIVANPTHITIGIYFKPELMPIP
                     MISVYETNQRALAVRAYAEKVGVPVIVDIKLARSLFKTHRRYDLVSLEEIDEVLRLLV
                     WLEEVENAGKDVIQPQENEVRH"
     gene            16490..16987
                     /gene="sicA"
                     /locus_tag="OPV72_001753"
     CDS             16490..16987
                     /gene="sicA"
                     /locus_tag="OPV72_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SycD/LcrH family type III secretion system
                     chaperone SicA"
                     /protein_id="HCR9914082.1"
                     /translation="MDYQNNVSEERVAEMIWDAVSEGATLKDVHGIPQDMMDGLYAHA
                     YEFYNQGRLDEAETFFRFLCIYDFYNPDYTMGLAAVCQLKKQFQKACDLYAVAFTLLK
                     NDYRPVFFTGQCQLLMRKAAKARQCFELVNERTEDESLRAKALVYLEALKTAETEQHS
                     EQEKE"
     gene            16990..18771
                     /gene="sipB"
                     /locus_tag="OPV72_001754"
     CDS             16990..18771
                     /gene="sipB"
                     /locus_tag="OPV72_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system needle tip
                     complex protein SipB"
                     /protein_id="HCR9914083.1"
                     /translation="MVNDASSISRSGYTQNPRLAEAAFEGVRKNTDFLKAADKAFKDV
                     VATKAGDLKAGTKSGESAINTVGLKPPTDAAREKLSSEGQLTLLLGKLMTLLGDVSLS
                     QLESRLAVWQAMIESQKEMGIQVSKEFQTALGEAQEATDLYEASIKKTDTAKSVYDAA
                     AKKLTQAQNKLQSLDPADPGYAQAEAAVEQAGKEATEAKEALDKATDATVKAGTDAKA
                     KAEKADNILTKFQGTANAASQNQVSQGEQDNLSNVARLTMLMAMFIEIVGKNTEESLQ
                     NDLALFNALQEGRQAEMEKKSAEFQEETRKAEETNRIMGCIGKVLGALLTIVSVVAAV
                     FTGGASLALAAVGLAVMVADEIVKAATGVSFIQQALNPIMEHVLKPLMELIGKAITKA
                     LEGLGVDKKTAEMAGSIVGAIVAAIAMVAVIVVVAVVGKGAAAKLGNALSKMMGETIK
                     KLVPNVLKQLAQNGSKLFTQGMQRITSGLGNVGSKMGLQTNALSKELVGNTLNKVALG
                     MEVTNTAAQSAGGVAEGVFIKNASEALADFMLARFAMDQIQQWLKQSVEIFGENQKVT
                     AELQKAMSSAVQQNADASRFILRQSRA"
     gene            18799..20028
                     /gene="sipC"
                     /locus_tag="OPV72_001755"
     CDS             18799..20028
                     /gene="sipC"
                     /locus_tag="OPV72_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system needle tip
                     complex protein SipC"
                     /protein_id="HCR9914084.1"
                     /translation="MLISNVGINPAAYLNNHSVENSSQTASQSVSAKDILNSIGISSS
                     KVSDLGLSPTLSAPAPGVLTQTPGTITSFLKASIQNTDMNQDLNALANNVTTKANEVV
                     QTQLREQQAEVGKFFDISGMSSSAVALLAAANTLMLTLNQADSKLSGKLSLVSFDAAK
                     TTASSMMREGMNALSGSISQSALQLGITGVGAKLEYKGLQNERGALKHNAAKIDKLTT
                     ESHSIKNVLNGQNSVKLGAEGVDSLKSLNMKKTGTDATKNLNDATLKSNAGTSATESL
                     GIKNSNKQISPEHQAILSKRLESVESDIRLEQNTMDMTRIDARKMQMTGDLIMKNSVT
                     VGGIAGASRQYAATQERSEQQISQVNNRVASTASDEARESSRKSTSLIQEMLKTMESI
                     NQSKASALAAIAGNIRA"
     gene            20098..21120
                     /gene="sipD"
                     /locus_tag="OPV72_001756"
     CDS             20098..21120
                     /gene="sipD"
                     /locus_tag="OPV72_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system needle tip
                     complex protein SipD"
                     /protein_id="HCR9914085.1"
                     /translation="MLNIQNYSASPHPGIVAERPQTPSASEHAEIAVVPSTTEHRGTD
                     IISLSQAATKIQQAQQTLQSTPPISEENNDERTLARQQLTSSLNALAKSGVSLSAEQN
                     ENLRSTFSAPTSALFSASPMAQPRTTISDAEIWDMVSQNISAIGDSYLGVYENVVAVY
                     TDFYQAFSDILSKMGGWLSPGKDGNTIKLNVDSLKSEISSLINKYTQINKNTILFPSQ
                     TGSGMTTATKAEAEQWIKELNLPDSCLKASGSGYVVLVDTGPLSKMVSDLNGIGSGSA
                     LELDNAKYQAWQSGFKAQEENLKTTLQTLTQKYSNANSLYDNLVKVLSSTISSSLETA
                     KSFLQG"
     gene            21139..23196
                     /gene="sipA"
                     /locus_tag="OPV72_001757"
     CDS             21139..23196
                     /gene="sipA"
                     /locus_tag="OPV72_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system effector SipA"
                     /protein_id="HCR9914086.1"
                     /translation="MVTSVRTQPPVIMPGMQTEIKTQATNLAANLSAVRESATATLSG
                     EIKGQQLEDFPALIKQASLDALFKCGKDAEALKEVFTNSNNVAGKKAIMEFAGLFRSA
                     LNATSDSPEAKTLLMKVGAEYTAQIIKDGLKEKSAFGPWLPETKKAEAKLENLEKQLL
                     DIIKNNTGGELSKLSTNLVMQEVMPYIASCIEHNFGCTLDPLTRSSLTQLVDKAAAKA
                     VEALDMCHQKLTQEQGTSVGREARHLEMQTLIPLLLRNVFAQIPADKLPDPKIPEPAA
                     GPVPDGGKKAEPTGINININIDSSNHSVDNSKHINNSRSHVDNSQRHIDNSNHDNSRK
                     TIDNSRTFIDNSQRHGESHHSTNSSNVSHSHSRVDSTTHQTETAHSASTGTIDHGIAG
                     KIDVTAHATAEAVTNSSSESKDGKVVTSEKGTTGETTSFDEVDGVTSKSIIGKPLQAT
                     VHGVDDNKQQSQTAEIVNVKPLASQLAGVENVKIDTLQSDSTVITGNKAGTTDNDNSQ
                     TDKTGPFSGLKFKQNSFLSTVPSVTNMHSIHFNAREAFLGVIRKALEPDASTPFPVRR
                     AFDGLRGEILPNDTIKSAALKAQCSDIDKHPELKAKMETLKEVITHHPQKEKLAEIAL
                     QFAREAGLTRQKGETDYVLSNVLDGLIGDGSWRAGPAYESYLNKPGVDRVITTVDGLH
                     MQR"
     gene            23215..23463
                     /locus_tag="OPV72_001758"
     CDS             23215..23463
                     /locus_tag="OPV72_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HCR9914087.1"
                     /translation="MNMDIEARVKKVITSCIAVDVDSINGQTHLVEDLYADSLDLIDI
                     VFGLSEEFDISCNENDLPDMTTFADICRVVKKSLESRV"
     gene            23507..>23677
                     /locus_tag="OPV72_001759"
     CDS             23507..>23677
                     /locus_tag="OPV72_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_449260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914088.1"
                     /translation="MKIITHVVPGSGMAAIYDDIADSSRFVIKGKLRHVENDPKELLI
                     CVPMRSEWLFYWI"
BASE COUNT         6444 a         4941 c         6124 g         6168 t
ORIGIN      
        1 aaaaaaagac agattgcctg aacagaaaga accggtgtca atgtagattt gattggcgaa
       61 tgttgttgtg taatcaacaa tcatatggcc gaagatgaaa gtatccgcac cgcgtattgg
      121 atggatattc ccctgtaacg aactaagcag acgatcgcgt gaccatagaa cgctatcaat
      181 atcaacttgc ttcccataat cgtagctgtc atctggataa tcggcatggg caatcacgta
      241 cttctttgag gacgttttaa cctctatgat gtgaggacgc tgcttaaaag ttagtaatag
      301 ctcagtggct tcttgcctgt ctttttgggt gaccgagtcg taccagtaac caccgtttac
      361 ataccagaaa ttgccatcct gtgtttcaaa agcgtcaagc gccatagctt catgattacc
      421 cactacagaa ataaaccatg aggtatttaa cagtctcagt gtttcaaggt tttcttttcc
      481 tcgatcaatg ttatctccag tggagatcaa gagatcggta tcaggagaga aatttaattg
      541 agccagtctg gttaacaata aggagtaaca tccatgaata tcaccaacga cccaaatgtg
      601 gcgatagaga acgctgttga tgtcagcata acgaattaat tccatgatgt tcctatagca
      661 caattttgga ggctggtatt ataacaaaga agtagggtaa tattaatttt tattgtttaa
      721 aatacacagt tattaaaata gcctacaagc tagaaatgaa cagataatat atattttatg
      781 aatcggttaa ttaaagtaga cgatgtgctt gaaagatgcg ctatttctcg cgcaacactt
      841 tcctgattaa ttgcaaaggc atactttccc gctcagcggc acgacagatg cgcaggcact
      901 gccggggctg attagccaga ctcaccgtaa aatcagggaa gcctcggctg acggcgctta
      961 tgacacgcgc tattgccatg atgtgttatt aatcaggccg ctaatcccgc cacgaagcgg
     1021 tgcgcgatac tggccgggca agtaccatga gcgtaaccac gcggtggcga atcaacatct
     1081 gagcggcagc aatgaggtct ggaaaagaaa gtgggctatc accgttgttc agtagtggaa
     1141 acagcgatgt tccgtctcaa aaccttgctg ggcggccatc tgagcctgcg gaactatgac
     1201 gcgcaggtgg gtgaagcgat ggcgatggcg atggtcaaag cgctgaaccg gatgacgttg
     1261 ttggcaatgc tgaccagcgt caggctcgta taacgagtgc tccggtggga gtcctgtatc
     1321 cttatcgttg gccgattctg aattattcaa caaagcctca tgttgtcata acctaccaga
     1381 tgcagataaa gcagcataaa gcgttttaaa cgacagcaac aaggaaaggg gttgatcgtt
     1441 taatggtact gcgccaaatc ctttgtacca gtcgcagacc tgtttatttt tggcatcaat
     1501 aagcagggct acgccaccga cctgcaaagc cgcctgtatg caacgctttc cggcagataa
     1561 caaaagttgt gctcccagcc cttgcccctg catagatttg tctacggcta aacgacccag
     1621 acgaaacact ggcacatcat atctccctaa tcctttgctg attgcgccgg gaacctgtgc
     1681 atatatcagt gatgcaggac tgactgagta aaagccgtgg atacgtgtaa catccgaatt
     1741 atcaagcgca acgtaggttt ttgttgtccc tttctcatga ttttgtcgtg catggcgttg
     1801 caggaattgg ttcagatcgg catccccaca atcaaaattc attcgattgt gggttttccc
     1861 tatcgcggcc tcatgccagt ctgtaaacat catttcttca tgtccggcag ggcgaaagca
     1921 gcggcaagaa gcttttcatt cggcgctggc gggttatcta aaatttccat gatcatttga
     1981 gtatcacgct ccgtcagata tacccgttcg gcggcatcaa caatcttctg tgcgacaggt
     2041 agtacgttac tgaccacaaa atccgtcagg ttggtttgct ggattgccgc agcgcggact
     2101 atcaactttt tggcatccgt cgatacacgt aacgacaatc tttcgttaga ttctatagct
     2161 atctgaggca tggttttcat cctcctgttt atgaacaata tgtacaatta taatacatat
     2221 ctgtacgctt tcaaagcgta catgtgaggc tgatatagtc caggcatggc aagaaggtcg
     2281 ttcactgtct ttaaacaggg cattaacttc ggtttatcgc gattgcatta ttttaatctc
     2341 actgattacg tatcatcagg gagtttgcta aatatattca tgattctctt ttttgccgta
     2401 actgcttgat tgatcctacc cgcgtagtat ggacacaacc ctaagcggcg gacatctcct
     2461 gctcacgttc agaagaagag agctgagttt gctgtttgct tcgccagctg tagagctgtg
     2521 atttatacag gttaagctca cgggcggcag cgggcacccc aatgcgttcc gccagtttca
     2581 gggcttcctg acgaaattca ggcgtgtgct gcttgcgtgg ctttttggtg gttgatgctg
     2641 gttttgttat gtgagtcacc tcttgcttga gcgtttactc acttagttgt gtgtccacta
     2701 ttgctgggta agttcaaaag aacgttatcc gcgaaaagtg gatggggtat cgtaagaatg
     2761 ccaacatgtg gggcaagagg gggatgtcag tttatcgcga tatacgagac gatagtttat
     2821 cagtataagt ttcggctatt ttcccgagtt tgggaggccg ttctttatca caaataaaaa
     2881 aagcagcagc gaggtgctgc tgtatcaaaa agcagattga taaatgcaac gtaagagaca
     2941 aatggccaac cgtaaaagtg accatagcta taataattat attgatatta agtggcaatg
     3001 caaagtatgg tcttaattat atcatgatga gttcagtcag cggtgatatg gccttataag
     3061 gcttgcagtc tttcatgggc agcaagtaac gtctgatata tgcttaaatt cttacttccg
     3121 ggttcaagta gaactttttt aaattcggtc atgagttgct cttcatcttc tttcgaacgc
     3181 atgtattgtg gatgttcctg gaagaaggta agcgcctgtt ctttggtttg tttatatttt
     3241 tcgcaaaaaa tgcttgagct gattgcgcta ttttttgatg cggaattatc agcgttctgg
     3301 tttgataatg atttattctt cgcaaggtct gacggcacat acggaagaga ctgacactca
     3361 tcaatactat ttgcgttggc cagttgctct ttctgagcgc caggttgctg taccggtttg
     3421 ctcacggagg aagggagggg cacctgggca cagccgatca gtaaaaagac aggaagacag
     3481 ctataaaatt ttttcatatt aactccaact acagaagaat gaggcgccat gtttttacac
     3541 aaccgtcaga atgttatctg acaatagtga taaggggcga atgcgtttca ggaatgctag
     3601 caaaaaaaac tcctgatata aataattaat tctccatccc gatgacaata tctgaatttt
     3661 tgctgctgta gaacaataag ccataatttg tatactatga gctgattttc tattttaaat
     3721 cagcaagcgc tgtgcaagtt ggctaattta attagcgggt ggcatcagtt tcataatgat
     3781 tgcatcagga ttttgccacc cgctcctggt attgtttaca tattaaaatg atttttaact
     3841 ggtgctgaca acaatgctaa atacgcagga agtacttaaa gaaggagaga agcggaaaat
     3901 ccgcagcccg gaagcatggt ttatacagac gtgttccgcg caaaagctgc atatgtcatt
     3961 ttctgaaagc cgacacaatg aaaactgcct gattcaggaa ggcgcgctgc ttttttgcga
     4021 gcaggccgtt gtcgcaccag tatcaggaga cctggttttt cgatcgttaa aaattgaagt
     4081 actcagcaaa ttactggcat ttatcgatgg cgcaggatta gtggacacga catatgctga
     4141 atccgataaa tgggttttgc tgagtcctga gtttcgcgct atttggcaag atcgtaaacg
     4201 ctgcgagtac tggtttttgc agcaaattat tacgccttct ccggccttca ataaggtact
     4261 ggcgctgtta cgaaaaagcg agagttactg gttggttggc tatttactcg ctcagtcaac
     4321 cagcggcaac acgatgagaa tgctgggaga agactatggc gtttcttata cccattttcg
     4381 tcgtttgtgc agcagagcgt tgggcggaaa agcgaagagt gaattacgaa actggcgtat
     4441 ggcgcaatcg ctgctgaata gtgtagaagg ccacgagaac atcacccaat tagccgttaa
     4501 tcatggttac tcatcgcctt cacatttttc tagtgagatc aaagagctga tcggcgtttc
     4561 gccgcggaaa ttatcaaata ttattcaatt ggcagacaaa tgaagacaca tattcttttg
     4621 gccagagtgc tggcatgtgc cgcgcttgtt ctggttgcac ctggttattc tagtgaaaaa
     4681 atacctgtaa cgggaagtgg gtttgttgcg aaagacgata gcctgcggac atttttcgat
     4741 gccatggcgc tacagctaaa ggagcctgtc attgttagca aaatggcggc acgaaaaaaa
     4801 attacgggca actttgagtt tcacgatcct aacgcattac tggagaagct ttccctacaa
     4861 ctggggctga tttggtattt cgatgggcag gctatctata tttatgacgc cagtgaaatg
     4921 cgcaatgccg tggtttcttt acgcaacgtc tcactcaatg agttcaacaa ttttctaaaa
     4981 cgctcaggtt tatataacaa aaattacccg ctacgtggcg ataaccgtaa aggaacattc
     5041 tatgtttcag ggccacccgt ctatgttgat atggtggtca acgccgccac catgatggac
     5101 aagcaaaacg atggtattga gctgggacgc cagaaaatag gggtgatgcg tctgaacaat
     5161 accttcgtgg gcgatcgtac ctacaatctg cgcgatcaga aaatggttat tcccggtatt
     5221 gctacggcca ttgaaaggtt attgcaggga gaagagcaac ccttaggtaa tattgtcagt
     5281 agcgaacccc cggcgatgcc agcattttca gcgaatggag aaaaaggtaa agcagcaaat
     5341 tatgccggtg gcatgagtct gcaggaagct ttaaagcaaa atgccgcggc gggcaatatt
     5401 aaaatcgtgg cctatccgga taccaacagt ttgttagtaa agggaacggc tgggcaggtg
     5461 cattttatcg aaatgctggt taaagcgctg gatgtcgcca aacgtcacgt agaattatcc
     5521 ctgtggattg tcgatcttaa taaaagcgat ctggagcgtt tgggcacttc atggagcggc
     5581 agcataacta ttggggacaa acttggcgtg tcattaaacc agtcttcaat aagtaccctc
     5641 gatggcagtc gattcatcgc cgcggtcaat gcgttagaag agaagaaaca ggcgacggtg
     5701 gtttcgcgtc cggtattact gactcaggaa aatgttcccg ctatttttga taacaacaga
     5761 acgttttaca ccaagctgat tggggaacgt aatgtggcgc ttgagcatgt aacatacgga
     5821 acaatgatcc gagtgctgcc ccgtttttcc gcagatggtc agatagaaat gtcgctggac
     5881 attgaagatg gcaacgataa gacgccgcaa tccgatacta ccacctccgt agatgcgtta
     5941 cccgaagtcg ggcgaacgtt aattagcact attgcaagag ttccgcacgg aaaaagtttg
     6001 ctggtcggtg gttatacacg ggatgcaaat accgatactg tccaaagtat tccggtttta
     6061 ggcaaattac cgcttattgg tagcctgttc cgttattcca gtaagaataa aagtaatgtt
     6121 gttcgtgtgt tcatgattga accaaaagaa attgtcgacc cgttaacgcc ggatgccagc
     6181 gaatcggtaa acaatattct gaagcaaagc ggtgcctgga gtggggacga taagttacag
     6241 aaatgggttc gtgtttatct ggatagaggt caggaggtaa ttaaatgatt cctggctcaa
     6301 cctctggtat ttcattttcc agaatattgt cccggcaggc atctcatcag gatgcgaccc
     6361 aacatactga tgcgcaacag gcggaaatac aacaggccgc agaggattcg tctccagggg
     6421 cggaagtaca aaaatttgtc cagtcgacgg acgaaatgtc agcggcgctg gcgcaatttc
     6481 gtaaccgtcg cgattatgaa aaaaaatcca gtaatttatc taacagtttt gaacgcgtgc
     6541 tggaggatga ggctttaccg aaggcgaagc aaatattaaa gctaattagc gtacatggcg
     6601 gcgcgttaga agatttttta cgtcaggcgc gtagcttatt tcctgacccc agtgatttag
     6661 tccttgtgtt acgcgaattg cttcgtcgta aagacctgga agagatcgtg cggaaaaagc
     6721 tggagtcgtt acttaagcac gttgaagagc aaaccgatcc gaagaccctc aaggcaggga
     6781 ttaattgtgc gttgaaggcc cggctttttg ggaaaacatt atcgttaaaa ccaggcttat
     6841 tgcgcgccag ctatcggcaa tttatccaga gtgaatcaca tgaagtggag atttactctg
     6901 actggatagc cagttatggc tatcaacgtc gactggtggt actggatttt atcgagggtt
     6961 cgctattaac cgatattgac gcgaatgacg ccagctgttc gcgcctggag tttggccagc
     7021 ttttacgacg cctgacgcaa cttaaaatgt tgcgctccgc tgacctactg tttgtgagta
     7081 cattgttgtc gtattcgttt accaaagcgt ttaatgcgga ggagtcgtcg tggctactac
     7141 tgatgctttc gctattgcaa cagccacatg aagtggattc gctgttagcc gatattatag
     7201 gtttgaatgc gttattgctt agtcataaag aacatgcatc ctttttgcag atattttatc
     7261 aagtatgtaa agccataccc tcttcactct tttatgaaga atattggcag gaagaattgt
     7321 taatggcgtt acgtagtatg accgatattg cctacaagca tgaaatggca gaacagcgtc
     7381 gtactattga aaagctgtct taatttaata ttaacaggat acctatagtg ctgctttctc
     7441 tacttaacag tgctcgttta cgacctgaat tactgattct ggtactaatg gtgatgatca
     7501 tttctatgtt cgtcattcca ttacctacct atctggttga tttcctgatc gcactgaata
     7561 tcgtactggc gatattggtg tttatggggt cgttctacat tgacagaatc ctcagttttt
     7621 caacgtttcc tgcggtactg ttaattacca cgctctttcg tctggcatta tcgatcagta
     7681 ccagccgtct tatcttgatt gaagccgatg ccggtgaaat tatcgccacg ttcgggcaat
     7741 tcgttattgg cgatagcctg gcggtgggtt ttgttgtctt ctctattgtc accgtggtcc
     7801 agtttatcgt tattaccaaa ggttcagaac gcgtcgcgga agtcgcggcc cgattttctc
     7861 tggatggtat gcccggtaaa cagatgagta ttgatgccga tttgaaggcc ggtattattg
     7921 atgcggatgc tgcgcgcgaa cggcgaagcg tactggaaag ggaaagccag ctttacggtt
     7981 cctttgacgg tgcgatgaag tttatcaaag gtgacgctat tgccggcatc attatcatct
     8041 ttgtgaactt tattggcggt atttcggtgg ggatgacccg ccatggtatg gatttgtcct
     8101 ccgctctgtc tacttatacc atgctgacca ttggtgatgg tcttgtcgcc cagatccccg
     8161 cattgttgat tgcgattagt gccggtttta tcgtgactcg cgtaaatggc gatagcgata
     8221 atatggggcg gaatatcatg acgcagctgt tgaacaaccc atttgtattg gttgttacgg
     8281 ctattttgac catttcaatg ggaactctgc cgggattccc gctgccggta tttgttattt
     8341 tatcggtggt tttaagcgta ctcttctatt ttaaattccg tgaagcaaaa cgtagcgccg
     8401 ccaaacctaa aaccagcaaa ggcgagcagc cgctcagtat tgaggaaaaa gaagggtcgt
     8461 cgttaggact gattggcgat ctcgataaag tctctacaga gactgtaccg ttgatattac
     8521 ttgtgccgaa gagccggcgt gaagatctgg aaaaagctca acttgcggag cgcctacgta
     8581 gtcagttctt tattgattat ggcgtgcgcc tgccggaagt attgttacgc gatggcgagg
     8641 gcctggacga taacagcatc gtattgttga ttaatgagat ccgtgttgaa caatttacgg
     8701 tctattttga tttgatgcga gtggtaaatt attccgatga agttgtttcc tttggcatta
     8761 atccaacaat ccatcagcaa ggtagcagtc agtatttctg ggtaacgcat gaagaggggg
     8821 agaaactccg ggagcttggc tatgtgttgc ggaacgcgct tgatgagctt taccactgtc
     8881 tggcggtgac gctggcgcgc aacgtcaatg aatatttcgg tattcaggaa acaaaacata
     8941 tgctggacca actggaagcg aaatttcctg atttacttaa agaagtgctc agacatgcca
     9001 cggtacaacg tatatctgaa gttttgcagc gtttgttaag cgaacgtgtt tccgtgcgta
     9061 atatgaaatt aattatggaa gcgctcgcat tgtgggcgcc aagagaaaaa gatgtcatta
     9121 accttgtgga gcatattcgt ggagcaatgg cgcgttatat ttgtcataaa ttcgccaatg
     9181 gcggcgaatt acgagcagta atggtatctg ctgaagttga ggatgttatt cgcaaaggga
     9241 tccgtcagac ctctggcagt accttcctca gccttgaccc ggaagcctcc gctaatttga
     9301 tggatctcat tacacttaag ttggatgatt tattgattgc acataaagat cttgtcctcc
     9361 ttacgtctgt cgatgtccgt cgatttatta agaaaatgat tgaaggtcgt tttccggatc
     9421 tggaggtttt atctttcggt gagatagcag atagcaagtc agtgaatgtt ataaaaacaa
     9481 tataagggct taattaagga aaagatctat gcaacatttg gatatcgctg aattagttcg
     9541 ttccgcactg gaagtaagtg gttgcgatcc ttcattaatt ggaggaatag atagccattc
     9601 aacaattgtt ctggatttat ttgcattgcc aagtatctgt atcagcgtca aggacgatga
     9661 tgtatggatc tgggcgcaat tgggtgctga cagcatggtg gtattacaac agcgggctta
     9721 tgaaatctta atgaccataa tggaaggatg ccattttgcc cgcggcgggc aattactact
     9781 gggggagcag aatggggagc taacgcttaa agccttagtg catccggatt ttttatctga
     9841 cggtgaaaag ttctctactg ccttgaatgg gttttacaac tatctggaag tttttagtcg
     9901 gtcgctaatg agatgaaaac acctcgttta ctgcaatatc tggcctaccc acaaaaaata
     9961 accggcccaa ttattgaggc ggaattgcgc gatgtggcca ttggcgaact gtgtgaaata
    10021 cgccgtggct ggcaccaaaa acaggttgtt gcacgtgcgc aggtggttgg cttacagcgg
    10081 gaacgcaccg tgctgagcct tatcggcaat gcccaggggc tgagccgcga tgtcgtgctt
    10141 tatcccactg gacgtgcgtt atcggcgtgg gtgggatact cagtattagg cgcggtgttg
    10201 gatccgacag ggaaaatcgt tgagcgtttt acccctgaag tggcgccgat tagcgaagaa
    10261 cgcgttattg atgtcgcacc gccgtcttac gcttcgcgcg ttggcgtccg tgaaccgctg
    10321 attaccggtg tgcgcgcgat tgacgggtta ttgacctgtg gcgtaggcca gcgaatgggc
    10381 atttttgcct ccgcaggatg cggtaagacc atgctgatgc atatgctgat cgagcaaacg
    10441 gaggcggatg tctttgttat cggtcttatc ggtgaacgag gccgtgaggt cactgaattc
    10501 gtggatatgt tgcgcgcttc gcataagaaa gaaaaatgcg tgctggtttt tgccacttcc
    10561 gatttcccct cggtcgatcg ctgcaatgcg gcgcaactgg cgacaaccgt agcggaatat
    10621 tttcgcgacc agggaaaacg ggtcgtgctt tttatcgatt ccatgacccg ttatgcgcgt
    10681 gctttgcgag atgtggcact ggcgtcggga gagcgtccgg cccgtcgagg ttatcccgcc
    10741 tccgtattcg ataatttgcc ccgcttgctg gaacgccccg gggcgaccag cgagggaagc
    10801 attactgcct tttatacggt actgctggaa agcgaggaag aggcggaccc gatggcggat
    10861 gaaattcgct ctatccttga cggtcacctg tatctgagca gaaagctggc cgggcaggga
    10921 cattacccgg caatcgatgt actgaaaagc gtaagccgcg tttttggaca agtcacgacg
    10981 ccgacacatg ctgaacaggc atctgccgtg cgtaaattaa tgacgcgtct ggaagagctc
    11041 cagcttttca ttgacttggg agaatatcgt cctggcgaaa atatcgataa cgatcgggcg
    11101 atgcagatgc gggatagcct gaaagcctgg ttatgccagc cggtagcgca atattcatcc
    11161 tttgatgaca cgttgagcgg tatgaatgca ttcgctgacc agaattaaag ttttacagcg
    11221 gcgctgtacg gtatttcatt cacagtgtga gtcaatatta cttcgctatc aggatgagga
    11281 ccgcgggctg caggccgagg aggaggcgat ccttgaacaa atagcgggtc tgaaattgtt
    11341 attagatacg ctgcgtgcag aaaacagaca gctcagtcgt gaggaaattt atacgttatt
    11401 acgtaagcag tctattgttc gccggcagat aaaagattta gaactccaga ttatacaaat
    11461 tcaggaaaaa cggagcgagc tggaaaagaa aagggaagag tttcagaaaa aaagtaaata
    11521 ttggttgcgc aaagaaggga actatcaacg ctggataatt cgtcagaaaa gacactatat
    11581 ccagcgagag atacagcagg aagaggccga gtcagaggag ataatttaat gggcgatgtg
    11641 tcagctgtca gttcatccgg gaacatttta ctgccgcagc aggatgaggt tggcggttta
    11701 tcagaagcat taaaaaaaac ggtggaaaaa cataagacag aatattccgg tgataaaaaa
    11761 gatcgcgact atggcgatgc tttcgtaatg cataaagaaa cggctttacc ggtattactg
    11821 gcggcatggc gacattgcgc gccagcgaaa tcagaacatc acaatggcaa cgtttctggt
    11881 ctgcatcata acggaaaagg cgaactcagg attgctgaaa aactgttgaa agtcactgct
    11941 gaaaaatctg tcggtttgat ttctgcggag gccaaagtag ataaatccgc agcgttgcta
    12001 tcgcctaaaa ataggccgtt agaaagcgta agcggtaaaa aattatctgc tgatttaaaa
    12061 gccgtggaat ccgttagtga agtaaccgat aatgccacgg gaatctctga cgataatatc
    12121 aaggcattgc ctggggataa taaagccatc gcgggcgaag gcgttcgtaa agagggcgcg
    12181 ccgctggcgc gggatgtcgc acctgcccga atggccgcag ccaataccgg taagcctgac
    12241 gataaagatc ataaaaaggt taaagatgtt tctcagcttc cgctgcaacc aaccactatc
    12301 gccgatctta gccaattaac cggcggcgat gaaaaaatgc ctttagcggc gcaatcaaag
    12361 ccgatgatga ctatttttcc cactgccgat ggcgtgaaag gagaggatag ctcgctgact
    12421 taccgttttc agcgctgggg aaatgactat tccgtcaata ttcaggcgcg gcaagcaggg
    12481 gagttttcgt taataccgtc aaatacgcag gttgaacatc gtttgcatga tcaatggcaa
    12541 aacggtaatc cccagcgctg gcacctgacg cgagacgatc aacaaaatcc gcagcagcaa
    12601 cagcacagac agcaatctgg cgaggaggat gacgcctgat gtcattgcgt gtgagacaga
    12661 ttgatcgtcg cgaatggcta ttggcgcaaa ccgcgacaga atgccagcgc catggccggg
    12721 aagcgacgct ggaatatccg acgcgacagg gaatgtgggt tcggttgagc gatgcagaaa
    12781 aacggtggtc ggcctggatt aaacctgggg gctggcttga gcatgtctct cccgctctgg
    12841 cgggggcggc ggtttctgcc ggtgctgagc acctggtcgt tccctggctt gctgcaacag
    12901 agcgaccgtt tgagttgccc gtgccgcatt tgtcctgtcg gcgtttatgc gtagagaacc
    12961 ccgtaccggg aagcgcgctg ccggaaggga aattgttgca cattatgagc gatcggggcg
    13021 gcctgtggtt tgagcatctt cctgaactgc ctgcagtcgg gggcggcagg ccgaaaatgc
    13081 tgcgttggcc gttgcgcttt gtaatcggta gcagtgatac gcagcgttct ttgctgggcc
    13141 gaatcgggat cggagatgta ctcctgattc gtacttcccg tgcggaagtt tattgctacg
    13201 cgaaaaagtt aggtcatttc aaccgtgttg aagggggaat tattgtggaa acgttagata
    13261 ttcaacatat cgaagaagaa aataatacaa ctgaaactgc agaaactctg cctggcttga
    13321 atcaattgcc cgtcaaactg gaatttgttt tgtatcgtaa gaacgttacc ctcgccgaac
    13381 tcgaagccat ggggcagcaa cagctattat cactgccgac caatgttgaa cttaacgttg
    13441 aaattatggc gaatggtgtt ttgcttggta atggcgaact ggtacagatg aatgacacct
    13501 taggcgttga gatccatgaa tggctgagcg agtctggtaa tggggaatga tatctcatta
    13561 attgccttac tggcattttc caccctgttg ccatttatta ttgcgtcagg aacctgtttc
    13621 gttaaatttt ctattgtatt tgtcatggtg cgtaacgccc tgggattgca gcagatacct
    13681 tcaaatatga cgcttaacag cgtcgcattg ctgctttcta tgtttgttat gtggccaata
    13741 atgcatgatg cctacgtcta ttttgaggac gaagatgtca cctttaatga tatttcgtca
    13801 ttaagtaaac acgttgatga aggtctggat ggttatcgcg attatctgat caaatattca
    13861 gatcgcgagt tagttcagtt ttttgaaaac gcgcaactga agcgtcagta tggagaagag
    13921 accgagacgg taaagcgtga caaagatgaa attgaaaaac catcaatatt tgcgttatta
    13981 cctgcttatg cgctgagcga aataaaaagc gcgtttaaaa ttggttttta tctctatttg
    14041 ccctttgttg tcgtcgacct ggtggtatcc agcgtgctac tggcgctggg gatgatgatg
    14101 atgagtccgg tgacgatatc tacacctatt aagctggtgc tttttgtcgc gcttgatggc
    14161 tggaccttac tgtctaaggg attgatatta cagtatatgg acattgcaac atgacatcat
    14221 tacgagacgg gatagttaaa tggatgattt agtgtttgca ggtaataagg cgctctatct
    14281 tgttttgatc ctgtcagggt ggccgacgat tgtcgcaacg attatcggcc tcctggtagg
    14341 gttattccag acggtaacgc aattacagga acagacgctg ccttttggca ttaaattact
    14401 tggcgtgtgt ttatgcttgt ttttactgtc tggctggtat ggcgaagttt tactctctta
    14461 cgggcgtcag gtgatattcc tggcgttggc taaggggtaa aaaatgcttt acgcgttgta
    14521 ctttgaaatt catcacctgg ttgcgtctgc ggcactaggg tttgctcgcg tagcgccgat
    14581 ttttttcttc ctgccgtttt tgaatagcgg ggtattaagc ggcgcgccga gaaacgccat
    14641 tatcatcctg gtggcattgg gagtatggcc gcatgcattg aacgaggcgc cgccgttttt
    14701 atcggtggcg atgatcccgt tagttctgca agaagcggcg gtaggcgtca tgctgggctg
    14761 tctgctgtca tggccttttt gggttatgca tgcgctgggt tgtattatcg ataaccagcg
    14821 aggggcaacg ctaagtagca gtatcgatcc ggcaaacggt attgatacct cggaaatggc
    14881 taatttcctg aatatgtttg ccgctgtcgt ttatttacaa aacggcggtc tggtcacgat
    14941 ggttgacgtg ttaaataaaa gctatcagct atgcgatccg atgaacgagt gcacgccttc
    15001 attaccgccg ctattaacgt ttattaatca ggtggctcaa aacgccttgg ttctggccag
    15061 tccggtggta ttagtgctgt tgctgtcaga agtattcctg ggtttattgt cgcgctttgc
    15121 tccgcaaatg aacgcttttg cgatttcact gacggtaaaa agcggcattg ccgttttaat
    15181 tatgctgctt tatttctctc cggtactacc ggacaatgta ccgcgactct ctttccaggc
    15241 cacagggtta agcagttggt tttacgagcg aggggcgacg catgtcctcg aataaaacag
    15301 aaaaaccgac taaaaaacgg ctggaagact ccgctaaaaa aggccagtca tttaaaagta
    15361 aagatctcat tatcgcctgt ctgacgctgg gaggaattgc ctatctggtg tcgtatggct
    15421 catttaatga gtttatgggg ataattaaga tcattattgc ggataatttt gatcagagca
    15481 tggctgatta cagtttggcc gtttttggga taggattaaa atatctgatt ccatttatgc
    15541 tgctctgttt agtgtgttcc gcattaccgg cgttattaca ggccggtttc gtgctggcga
    15601 cagaagcatt aaaacctaat ttatcggcgt taaacccggt agaaggggcg aaaaaacttt
    15661 ttagtatgcg cacggttaaa gatacggtca aaaccctact gtatctctca tcctttgtgg
    15721 tggccgccat catttgctgg aagaaatata aggttgaaat cttttctcag ttaaatggca
    15781 atgttgtgga tattgccgtc atttggcgtg aacttctcct cgcattggta ttaacttgcc
    15841 ttgcttgcgc attgattgtc ttattattgg atgctattgc ggaatatttc ctgaccatga
    15901 aagatatgaa aatggataag gaagaagtga agcgtgaaat gaaggagcag gaagggaacc
    15961 cagaggttaa atctaaaaga cgtgaagttc atatggaaat tctgtctgaa caggtgaaat
    16021 ccgatattga aaactcacgc ctgattgttg ccaaccccac gcatattacg atcgggattt
    16081 attttaaacc cgaattgatg ccgattccga tgatctcggt gtatgaaacg aatcagcgcg
    16141 cactggccgt ccgcgcctat gcggagaagg ttggcgtacc tgtgatcgtc gatatcaaac
    16201 tggcgcgcag tcttttcaaa acccatcgcc gttatgatct ggtgagtctg gaagaaattg
    16261 atgaagtttt acgtcttctg gtttggctgg aagaggtaga aaacgcgggc aaagacgtta
    16321 ttcagccaca agaaaacgag gtacggcatt gagccgcgta aagcagtagc gatgtattca
    16381 ttgggagttt tttgaatgtt cactaaccac cgtcggggtt taataactgc atcagataaa
    16441 cgcagtcgtt aagttctaca aagtcggtga cagataacag gagtaagtaa tggattatca
    16501 aaataatgtc agcgaagaac gtgttgcgga aatgatttgg gatgccgtta gtgaaggcgc
    16561 cacgctaaaa gacgttcacg ggatccctca agatatgatg gacggtttat atgctcatgc
    16621 ttatgagttt tataaccagg gacgactgga tgaagctgag acattctttc gtttcttatg
    16681 catttatgat ttttacaatc ccgattacac catgggactg gcggcggtat gccaactgaa
    16741 aaaacaattt cagaaagcat gtgaccttta tgcagtagcg tttacgttac ttaaaaatga
    16801 ttatcgcccc gtttttttta ccgggcagtg tcaattatta atgcgtaagg cggcaaaagc
    16861 cagacagtgt tttgaacttg tcaatgaacg tactgaagat gagtctctgc gggcaaaagc
    16921 gttggtctat ctggaggcgc taaaaacggc ggagacagag cagcacagtg aacaagaaaa
    16981 ggaataatta tggtaaatga cgcaagtagc attagccgta gcggatatac ccaaaatccg
    17041 cgcctcgctg aggcggcttt tgaaggcgtt cgtaagaaca cggacttttt aaaagcggcg
    17101 gataaagctt ttaaagatgt ggtggcaacg aaagcgggcg accttaaagc cggaacaaag
    17161 tccggcgaga gcgctattaa tacggtgggt ctaaagccgc ctacggacgc cgcccgggaa
    17221 aaactctcca gcgaagggca attgacatta ctgcttggca agttaatgac actactgggc
    17281 gatgtttcgc tgtctcaact ggagtctcgt ctggcggtat ggcaggcgat gattgagtca
    17341 caaaaagaga tggggattca ggtatcgaaa gaattccaga cggctctggg agaggctcag
    17401 gaggcgacgg atctctatga agccagcatc aaaaagacgg ataccgccaa gagtgtttat
    17461 gacgctgcgg ccaaaaaact gacgcaggcg caaaataaat tgcaatcgct ggacccagct
    17521 gaccccggct atgcacaagc tgaagccgcg gtagaacagg ccggaaaaga agcgacagag
    17581 gcgaaagagg ccttagataa ggccacggat gcgacggtta aagcaggcac agacgccaaa
    17641 gcgaaagccg agaaagcgga taacattctg accaaattcc agggaacggc taatgccgcc
    17701 tctcagaatc aggtttccca gggtgagcag gataatctgt caaatgtcgc ccgcctcact
    17761 atgctcatgg ccatgtttat tgagattgtg ggcaaaaata cggaagaaag cctgcaaaac
    17821 gatcttgcgc ttttcaacgc cttgcaggaa gggcgtcagg cggagatgga aaagaaatcg
    17881 gctgaattcc aggaagagac gcgcaaagcc gaggaaacga accgcattat gggatgtatc
    17941 gggaaagtcc tcggcgcgct gctaaccatt gtcagcgttg tggccgctgt ttttaccggt
    18001 ggggcgagtc tggcgctggc tgcggtggga cttgcggtaa tggtggccga tgaaattgtg
    18061 aaggcggcga cgggggtgtc gtttattcag caggcgctaa acccgattat ggagcatgtg
    18121 ctgaagccgt taatggagct gattggcaag gcgattacca aagcgctgga aggattaggc
    18181 gtcgataaga aaacggcaga gatggcaggc agcattgttg gtgcgattgt cgccgctatt
    18241 gccatggtag cggtcattgt ggtggtcgca gttgtcggga aaggcgcggc ggcgaaactg
    18301 ggtaacgcgc tgagcaaaat gatgggcgaa acgattaaga agttggtgcc taacgtgctg
    18361 aaacagttgg cacaaaacgg cagcaaactc tttacccagg ggatgcaacg tattactagc
    18421 ggcctgggta atgtgggtag caagatgggc ctgcaaacga atgccttaag taaagagctg
    18481 gtaggtaata ccctaaataa agtggcgttg ggcatggaag tcacgaatac cgcagcccag
    18541 tcagccggtg gggttgccga gggggtattt attaaaaatg ccagcgaggc gcttgctgat
    18601 tttatgctcg cccgttttgc catggatcag attcagcagt ggcttaaaca atccgtagaa
    18661 atatttggtg aaaaccagaa ggtaacggcg gaactgcaaa aagccatgtc ttctgcggta
    18721 cagcaaaatg cggatgcttc gcgttttatt ctgcgccaga gtcgcgcata aaaactgcca
    18781 aaataaaggg agaaaaatat gttaattagt aatgtgggaa taaatcccgc cgcttattta
    18841 aataatcatt ctgttgagaa tagttcacag acagcttcgc aatccgttag cgctaaagat
    18901 attctgaata gtattggtat tagcagcagt aaagtcagtg acctggggtt gagtcctaca
    18961 ctgagcgcgc ctgcgccagg ggtattaacg caaacccccg gaacgatcac gtccttttta
    19021 aaagccagta ttcaaaatac cgacatgaat caggatttga atgccctggc aaataatgtc
    19081 acgactaaag cgaatgaggt tgtgcaaacc cagttacgcg agcagcaggc agaagtcgga
    19141 aagttttttg atattagcgg aatgtcttcc agtgccgttg cgctgttggc tgccgcgaat
    19201 acgttaatgc tgacgttgaa ccaggctgat agcaaactgt ctggtaagtt gtcattagtc
    19261 agttttgatg cagctaaaac gacggcaagc tccatgatgc gcgaagggat gaatgcgttg
    19321 tccggtagta tttcccagag cgcgcttcag ttggggatca ctggcgtggg cgccaaactg
    19381 gaatataagg ggctgcagaa tgaaagaggc gcgcttaaac ataatgccgc gaagatcgat
    19441 aaactgacca ctgaaagcca cagtattaaa aacgtgctga acgggcagaa tagcgtcaaa
    19501 cttggtgctg aaggcgtcga ttctctgaaa tcgttaaata tgaagaaaac cggtaccgat
    19561 gcgacgaaaa atcttaatga tgcgacgctt aaatctaatg ccggaaccag cgccacggaa
    19621 agtctgggta ttaaaaacag taataaacaa atctcccctg aacatcaggc tattctgtcg
    19681 aaacgtcttg agtctgtcga atccgatatt cgtcttgagc agaataccat ggatatgacc
    19741 cgaatcgatg cgcgcaagat gcagatgacg ggcgatctga ttatgaagaa ctcagtcacg
    19801 gtcggtggta ttgcaggggc gtccaggcag tacgccgcta ctcaggaacg ttccgagcag
    19861 caaattagcc aggtgaataa ccgggttgcc agcaccgcat cggacgaagc ccgtgaaagt
    19921 tcacgtaaat cgaccagcct gattcaggaa atgctgaaaa caatggagag cattaaccag
    19981 tcgaaagcat ccgcactcgc tgctatcgca ggcaatattc gcgcttaatc tgacagatca
    20041 actatacgcc atcagggggg gatttaatcg ccctcctgat ggcgaactgg ggatattatg
    20101 cttaatattc aaaattattc cgcttctcct catccgggga tcgttgccga acggccgcag
    20161 actccttcgg cgagcgagca cgccgagatt gccgtggtac cgtctaccac agaacatcgc
    20221 ggcacagata tcatttcatt atcgcaggcg gctactaaaa tccagcaggc acagcagacg
    20281 ctgcagtcaa cgccaccgat ttctgaagag aataatgacg agcgcacgct ggcgcgccaa
    20341 cagttgacca gcagcctgaa tgcgctggcg aagtccggcg tgtcattatc cgcagaacaa
    20401 aatgagaacc tgcggagcac gttttctgcg ccgacgtcgg ccttatttag cgcttcgcct
    20461 atggcgcagc cgagaacaac catttctgat gctgagattt gggatatggt ttcccaaaat
    20521 atatcggcga taggtgacag ctacctgggc gtttatgaaa acgttgtcgc agtctatacc
    20581 gatttttatc aggccttcag tgatattctt tccaaaatgg gaggctggtt atcgcctggt
    20641 aaggatggaa ataccattaa gctaaatgtt gactcactta aaagtgaaat aagtagttta
    20701 attaataaat acactcaaat aaataaaaat acgattttat ttccctcgca aactggcagc
    20761 ggaatgacaa cagcaacgaa agcggaagct gagcagtgga ttaaagaatt gaatttaccg
    20821 gacagctgtc taaaggcgtc tggttctggt tatgtcgtac tggtggatac ggggccactg
    20881 agcaaaatgg ttagcgatct taatggaata ggatcgggtt cagcccttga actggataac
    20941 gccaaatatc aagcctggca gtcgggtttt aaagcacagg aagaaaatct gaaaaccaca
    21001 ttacagacgc tgacgcaaaa atatagcaat gccaattcat tgtacgacaa cctggtaaaa
    21061 gtgctgagca gtacgataag tagcagcctg gaaaccgcca aaagcttcct gcaaggataa
    21121 cagaagagga tattaataat ggttacaagt gtaagaactc agccccccgt cataatgcca
    21181 ggtatgcaga ccgagatcaa aacgcaggcc acgaatcttg cggcgaatct ttccgcggtc
    21241 agagaaagtg ccacagcaac gctgtcaggg gaaattaaag gccagcaact ggaagatttt
    21301 cccgcgctga tcaaacaggc gagtctggat gcgttgttta aatgcgggaa agacgccgag
    21361 gcgttaaaag aagtttttac caattcaaat aatgtcgccg gtaagaaagc gataatggag
    21421 tttgccggcc tctttcgttc agcgctcaac gccaccagtg attctcctga ggcgaagacg
    21481 ctactgatga aggtgggggc agagtatacc gcgcaaatca taaaagatgg cctgaaagaa
    21541 aagtcagctt ttgggccatg gctgccagaa acaaagaaag cggaagcgaa gctggaaaac
    21601 ctggaaaagc agctgttaga tatcatcaaa aataacactg gcggtgaatt aagtaaatta
    21661 tcgacgaatc ttgttatgca ggaggtgatg ccctatattg ccagctgcat tgaacataac
    21721 tttggctgta cgttagatcc gttaacccgc agcagtctta cgcagcttgt tgacaaagcg
    21781 gcggcgaagg cggttgaggc gcttgatatg tgccaccaaa aattaacgca agagcagggt
    21841 accagcgtag gacgggaagc ccggcacctt gaaatgcaaa cgttgatacc cctgctgcta
    21901 cgtaatgttt ttgcacaaat tcctgcagat aaactgcctg accctaaaat tccggaacct
    21961 gcggctggac cagtacctga tggtgggaaa aaagcagaac ctacgggtat taatatcaat
    22021 attaatattg atagcagtaa ccatagcgtg gataacagta agcatattaa caatagccga
    22081 agccatgtcg ataatagcca gcgccatatc gataatagca accatgataa tagccggaag
    22141 acgattgata atagccgaac atttattgat aacagccaac gccatggcga gtcacaccat
    22201 tcgactaaca gcagcaacgt aagtcatagt cattcgcgtg tggattcgac tacgcatcaa
    22261 acggagaccg cacacagcgc cagcacaggg acaattgacc atggcatcgc gggtaaaatt
    22321 gacgtcacgg ctcatgcgac ggcagaggct gtgaccaact cttcatccga aagtaaagat
    22381 ggaaaggtgg tcacgtcaga aaagggcact acgggtgaaa caacctcttt tgatgaagtc
    22441 gatggcgtaa ccagcaagag cattatcggc aagccgttac aggccacggt gcacggcgtt
    22501 gatgataata aacagcaaag ccagacggca gagattgtga atgtgaagcc gcttgccagt
    22561 caactggctg gcgtcgagaa tgttaaaatc gataccttac aatcagactc gacggtaatt
    22621 acaggtaata aagccggtac gaccgataat gataatagcc agacagataa gactggccca
    22681 ttttctggtt tgaagtttaa gcaaaatagt ttcctctcaa cagtaccgag cgttacgaat
    22741 atgcattcaa tacatttcaa cgcccgtgag gcgtttttgg gtgtgatacg taaagccctg
    22801 gagccggatg cctctacacc gtttcctgta cgcagagcgt ttgacggctt gcgtggggaa
    22861 atattaccca atgacacgat aaagagtgca gcgttgaaag cgcaatgtag cgatattgac
    22921 aagcacccag aattgaaagc gaaaatggag acgctcaaag aggtcattac tcatcatcca
    22981 caaaaagaaa aactggctga gattgcattg cagtttgcca gagaggcggg gttgaccagg
    23041 caaaaagggg aaactgacta tgtgttaagt aatgtgctgg acggccttat cggagacggt
    23101 agctggcgag ctggcccggc ttacgagtca tacctgaata aacctggtgt ggatcgggtt
    23161 attactaccg ttgatggctt gcacatgcag cgttaattaa ctgggaaaga tgcgatgaat
    23221 atggatattg aagcaagagt caaaaaagtg atcacctcct gtattgccgt tgatgttgat
    23281 agtatcaatg gtcagaccca tctggttgag gatctttacg ctgactcatt ggatttaatt
    23341 gatattgtat ttggtcttag tgaggagttt gacattagtt gtaatgaaaa cgatcttcct
    23401 gatatgacga cctttgcgga tatatgccgt gttgttaaaa aaagtcttga gtccagggtg
    23461 tagtattttt ctctcgctcg acaacaattg aacaagatta attgttatga aaatcatcac
    23521 acatgtagta cccggttcag gcatggctgc aatatatgat gatattgctg acagttcgcg
    23581 ttttgttatt aaaggcaagt tacgtcatgt tgaaaatgat ccgaaggaac tgctgatttg
    23641 tgttccgatg cgtagtgaat ggctattcta ctggatt
//
LOCUS       DAJVBX010000051        23660 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.051, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000051 DAJVBX010000000
VERSION     DAJVBX010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 23660)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23660)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23660
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.051"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..1420)
                     /locus_tag="OPV72_001760"
     CDS             complement(<1..1420)
                     /locus_tag="OPV72_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914089.1"
                     /translation="MDYINRWLGSELLMFCVLPWGYAAAVASLLILMFSKKRSRQILL
                     WVLLPQWAFVVLLLPTLQYTQLLSQTGTVWMLMLLLPILSWAGLLPALLLGTWLRKPW
                     PAWLLCHIVFIGMLCPVMPELWRAISYQWQQQNIAQLLRQVQAGDLRQLESIHDNSTL
                     EQTLVQAVKAPGISEKNLRDLTARVASPFRFSREDGYFVNAPFFAAFESGNITAVRIF
                     SEQLMGDSPQAQANRTIVRRQNPLEYLPTPRFKPEGFRQTFFEMADILLRVMPDLLTD
                     EAYSGAIQLQDKETLAFFWQRREAQNPLYRAYYFLLQGQTKALLAQIKLTPQVLGQSV
                     YPNKNLLASLFIDADGETLRALVKGQMLNWQHIPQDKLTDGWNFLISRTLHTASKEDA
                     LPPDILAGILQSMQQQHTALSEALIVASLDYQDERHSLMTAYRMAWLDCNKLNAMIDK
                     VYPPEDTRRTNVRIKLAQQCADL"
     gene            complement(1436..2395)
                     /locus_tag="OPV72_001761"
     CDS             complement(1436..2395)
                     /locus_tag="OPV72_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001765108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914090.1"
                     /translation="MASVLTLAAEHRDTPENLLRYLAKIRGISPFLTAAESCPEAAIP
                     NAEFLYTPFATALRQHNVPIVRFFSQQLVGETSSARENRNIVARKENPLLTLYKSNYI
                     SQYREQYRLEISQLLLNIMPELLNDTVYIYPIIQRNTELVAYFWQKHPPTIPLRRLEA
                     MVLLAKTESLISEVTHNPEILITPPIERWDRENLLTFILSNGDLVMIQSLIDANVVDW
                     KRAMEDGNNEPLHQAILRLRGGALENALLIQIIKAMQAQKALSNEQIAHYLPWTPTFP
                     AAFLQAGLSCEQLREVLNALVVGSEQVLHDTRQRLNALCPVAK"
     gene            complement(2474..2857)
                     /locus_tag="OPV72_001762"
     CDS             complement(2474..2857)
                     /locus_tag="OPV72_001762"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914091.1"
                     /translation="MGESFAWMMWDSVILMSAWGIYGVVLLRLIVGAFDSLRYRRVFL
                     RVVLPQVSVVCVVWGGLFWIDSKDIYIVYLLISGLLPSIIIAIFSSRESPFFILGTIV
                     SHTIFLFVFVYVMDGPRLWHHIGED"
     gene            complement(3041..3652)
                     /locus_tag="OPV72_001763"
     CDS             complement(3041..3652)
                     /locus_tag="OPV72_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914092.1"
                     /translation="MVVLLLLLAHMGDILDRHHRRDAYQAQQVAEETLLRKIDTTDDR
                     VFLNHLMSQAMQPQNAGDWGTNRRIEHLAKRISPFDIAGGTEKIWLVLAIDRLNRSAV
                     GTFASWFIGDSVQAKQYRHQLLQNNPLLDLLNRVFNDSTADEQTFLQQQLLARDICTS
                     LISVVPELLTDELYAQAVAFDNSNKPEPFSWQFEFDVFYHQKK"
     gene            complement(3806..3952)
                     /locus_tag="OPV72_001764"
     CDS             complement(3806..3952)
                     /locus_tag="OPV72_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001222143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914093.1"
                     /translation="MRINEEGWRLLTFWMFTTGGYLILLFVVICLAFLFQTPRRVLLW
                     IALP"
     gene            complement(3973..5385)
                     /gene="ftsP"
                     /locus_tag="OPV72_001765"
     CDS             complement(3973..5385)
                     /gene="ftsP"
                     /locus_tag="OPV72_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsP"
                     /protein_id="HCR9914094.1"
                     /translation="MSFSRRQFLQASGIALCAGAIPLRANAAGQQQPLPVPPLLESRR
                     GQPLFMTLQRAHWSFTQGTRAPVWGVNGRYLGPTIRVWKGDDVKLIYSNRLAENVSMT
                     VAGLLVPGPLMGGPARMMSPNADWAPVLPIRQSAATLWYHANTPNRTAQQVYNGLAGM
                     WLVEDDISKTLPIPNHYGVDDFPVIIQDKRLDNFGTPEYSEPGSGGFVGDTLLVNGAQ
                     SPYVEVSRGWVRLRLLNASNSRRYQLQMSDGRALHVISGDQGFLPAPVSVKQLSLAPG
                     ERREILVDMTNGDEVSITCGEAASIVDRIRGFFEPSSILVSTLVLTLRPTGLLPLVTD
                     NLPMRLLPTEIMSGAPVRSRDISLGDDPGINGQLWDVNRIDITAQQGTWERWTVRADM
                     PQSFHIEGVSFLIRNVNGAMPFPEDRGWKDTVWVDGQVELLVYYGQPSWPHFPFYFNS
                     QTLEMADRGSIGQMLVNPAS"
     gene            complement(5459..6196)
                     /gene="plsC"
                     /locus_tag="OPV72_001766"
                     /gene_synonym="parF"
     CDS             complement(5459..6196)
                     /gene="plsC"
                     /locus_tag="OPV72_001766"
                     /gene_synonym="parF"
                     /EC_number="2.3.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acylglycerol-3-phosphate O-acyltransferase"
                     /protein_id="HCR9914095.1"
                     /translation="MLYIFRLIVTVIYSILVCVFGSIYCLFSPRNPKHVATFGHMFGR
                     LAPLFGLKVECRKPADAENYGNAIYIANHQNNYDMVTAANIVQPPTVTVGKKSLLWIP
                     FFGQLYWLTGNLLIDRNNRAKAHSTIAAVVNHFKKRRISIWMFPEGTRSRGRGLLPFK
                     TGAFHAAIAAGVPIIPVCVSNTSNKVNLNRLNNGLVIVEMLPPVDVSEYGKDQVRELA
                     AHCRALMEQKIAELDKEVAEREATGKV"
     gene            complement(6453..8711)
                     /gene="parC"
                     /locus_tag="OPV72_001767"
     CDS             complement(6453..8711)
                     /gene="parC"
                     /locus_tag="OPV72_001767"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HCR9914096.1"
                     /translation="MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRR
                     IVYAMSELGLNATAKFKKSARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDG
                     QGNWGAPDDPKSFAAMRYTESRLSKYAELLLSELGQGTADWVPNFDGTMQEPKMLPAR
                     LPNILLNGTTGIAVGMATDIPPHNLREVAKAAITLIEQPKTTLDQLLDIVQGPDYPTE
                     AEIIIPRAEIRKIYENGRGSVRMRAVWTKEDGAVVITALPHQVSGAKVLEQIAAQMRN
                     KKLPMVDDLRDESDHENPTRLVIVPRSNRVDMEQVMNHLFATTDLEKSYRINLNMIGL
                     DGRPAVKNLLEILTEWLAFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEI
                     IRNEDEPKPALMSRFGISETQAEAILELKLRHLAKLEEMKIRGEQDELEKERDQLQGI
                     LASERKMNTLLKKELQADSDAYGDDRRSPLREREEAKAMSEHDMLPSEPVTIVLSQMG
                     WVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFIDTTGRSYAIDPITLPSARGQ
                     GEPLTGKLTLPPGATVEHMLMEGDDQKLLMASDAGYGFVCTFNDLVARNRAGKTLITL
                     PENAHVMPPLVIKDEHDMLLAITQAGRMLMFPVDSLPQLSKGKGNKIINIPSAEAAKG
                     DDGLAHLYVLPPQSTLTIHVGKRKIKLRPEELQKVVGERGRRGTLMRGLQRIDRIEID
                     SPHRVSHGDSEE"
     gene            complement(8822..9688)
                     /locus_tag="OPV72_001768"
     CDS             complement(8822..9688)
                     /locus_tag="OPV72_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCR9914097.1"
                     /translation="MNDLISAAYSERLRRVCDHIERHLDEPLSLEALSRMAHSSPFHF
                     HRQFTVWSGLPLYRYIQWLRLRRASWRLAFNPQDKVIDIALDAGFQNPESFTRAFKTA
                     FGQSPCRFRQSPDWLAWHQRVPKLALQEQHVMDVKIVEFPPTRVAMLTHLGHPDKVNA
                     SAAKFIAWRRETGQSPIASSQTFGIAWHDPQTTPPAQFRFDICGSVRQPIAENDVGVV
                     NSEIPGGRCAVVRHQGSLDSLPESVWYLFREWLPASGETLRDFPVFFQYLNFVHEVAE
                     HELLTDIYLPLR"
     gene            complement(9760..10152)
                     /locus_tag="OPV72_001769"
     CDS             complement(9760..10152)
                     /locus_tag="OPV72_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgiW/YdeI family stress tolerance OB fold
                     protein"
                     /protein_id="HCR9914098.1"
                     /translation="MKKLAAIVAVMALCSTPVLAAQQGGFSGPSATQTQGGGFVGPNG
                     SSTTVESAKSLRDDAWVTLRGNIVERISDDLYVFKDATGTINVDIDHKRWNGLTVTPQ
                     DTVEIQGEVDKDWNSVEIDVKQIRKVNP"
     gene            10304..10963
                     /gene="qseB"
                     /locus_tag="OPV72_001770"
     CDS             10304..10963
                     /gene="qseB"
                     /locus_tag="OPV72_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator QseB"
                     /protein_id="HCR9914099.1"
                     /translation="MRILLVEDDTLIGDGIKAGLSKMGFSVDWFTEGRPGKEALYSAP
                     YDAVILDLTLPGMDGRDILREWREKGKQEPVLILTARDALAERVEGLRLGADDYLCKP
                     FALIEVAARLEALVRRASGQASSELRHGQVTLNPGNLVATLAGEPLALKPKEFALLEL
                     LLRNKGRVLPRKLIEEKLYNWDDDVSSNAVEVHVHHLRRKLGSEFIRTVHGIGYTLGD
                     A"
     gene            10960..12309
                     /gene="qseC"
                     /locus_tag="OPV72_001771"
     CDS             10960..12309
                     /gene="qseC"
                     /locus_tag="OPV72_001771"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     QseC"
                     /protein_id="HCR9914100.1"
                     /translation="MKLTQRLSLRVRLTLIFLILVSITWAISSFVAWRKTTDNVDELF
                     DTQLMLFARRLSTLDLNELNAPQRMAHTPKKLKHGHIDDDALAFAIFSADGKMLLHDG
                     DNGQDIPYRYRREGFDNGYLKDDNDLWRFLWLNSADGKYRIVVGQEWDYREDMALAIV
                     AAQLTPWLIALPFMLLILLLLLHRELRPLKKLAQALRFRSPESETPLDAKGVPSEVRP
                     LVEALNQLFSRIHSMMVRERRFTSDAAHELRSPLAALKVQTEVAQLSGDDPLSRDKAL
                     TQLHAGIDRATRLVDQLLTLSRLDSLNNLQDVAEISLEELLQSAVMDIYHPAQQANID
                     VRLQLNAHDVIRTGQPLLLSLLVRNLLDNAIRYSPQGSVVDVTLHARSFTVRDNGPGV
                     APEILTHIGERFYRPPGQSVTGSGLGLSIVRRIATLHGMTVSFGNAAEGGFEAVVRW"
     gene            12416..12996
                     /locus_tag="OPV72_001772"
                     /pseudo
     CDS             12416..12996
                     /locus_tag="OPV72_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
     gene            13028..13342
                     /locus_tag="OPV72_001773"
     CDS             13028..13342
                     /locus_tag="OPV72_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HCR9914101.1"
                     /translation="MLTVIAEIRTRPGQHHRQAVLDQFAKIIPTVLKEEGCHGYAPMV
                     DHAAGVSFQTLAPDSIVMIEQWESVAHLEAHLQTPHMKAYSDAVKDDVLEMNIRILES
                     GV"
     gene            complement(13467..15359)
                     /gene="parE"
                     /locus_tag="OPV72_001774"
     CDS             complement(13467..15359)
                     /gene="parE"
                     /locus_tag="OPV72_001774"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HCR9914102.1"
                     /translation="MTQTYNADAIEVLTGLEPVRRRPGMYTDTTRPNHLGQEVIDNSV
                     DEALAGHAKRVDVILHADQSLEVIDDGRGMPVDIHPEEGVPAVELILCRLHAGGKFSN
                     KNYQFSGGLHGVGISVVNALSKRVEVTVRRDGQVYNIAFENGEKVQDLQVVGTCGKRN
                     TGTSVHFWPDESFFDSPRFSVSRLMHVLKAKAVLCPGVEITFKDEVNNSEQRWCYQDG
                     LNDYLGEAVNGLPTLPEKPFIGNFNGETEAVDWALLWLPEGGELLTESYVNLIPTMQG
                     GTHVNGLRQGLLDAMREFCEYRNILPRGVKLSAEDIWDRCAYVLSVKMQDPQFAGQTK
                     ERLSSRQCAAFVSGVVKDAFSLWLNQNVQAAEQLAEMAIASAQRRLRAAKKVVRKKLT
                     SGPALPGKLADCTAQDLNRTELFLVEGDSAGGSAKQARDREYQAIMPLKGKILNTWEV
                     SSDEVLASQEVHDISVAIGIDPDSDDLSQLRYGKICILADADSDGLHIATLLCALFVR
                     HFRALVKNGHVYVALPPLYRIDLGKEVYYALTEEEKAGVLEQLKRKKGKPNVQRFKGL
                     GEMNPMQLRETTLDPNTRRLVQLTISDEDDQRTNAMMDMLLAKKRSEDRRNWLQEKGD
                     LADLDV"
     gene            complement(15387..15968)
                     /gene="yqiA"
                     /locus_tag="OPV72_001775"
     CDS             complement(15387..15968)
                     /gene="yqiA"
                     /locus_tag="OPV72_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase YqiA"
                     /protein_id="HCR9914103.1"
                     /translation="MSTLLYLHGFNSSPRSAKACQLKNWLAERHPHVEMIVPQLPPYP
                     ADAAELLESLVLEHGGAPLGLVGSSLGGYYATWLSQCFMLPAVVVNPAVRPFELLTDY
                     LGQNENPYTGQQYVLESRHIYDLKVMQIDPLEAPDLIWLLQQTGDEVLDYRQAVAYYA
                     SCRQTVTEGGNHAFTGFEDYFNQIVDFLGLHSC"
     gene            complement(15968..16795)
                     /gene="cpdA"
                     /locus_tag="OPV72_001776"
     CDS             complement(15968..16795)
                     /gene="cpdA"
                     /locus_tag="OPV72_001776"
                     /EC_number="3.1.4.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3',5'-cyclic-AMP phosphodiesterase"
                     /protein_id="HCR9914104.1"
                     /translation="MESLLTLPLAGEARVRILQITDTHLFAEKHETLLGVNTWESYQA
                     VLEAIRAQQYEYDLIVATGDLAQDQSAAAYQHFAEGIASFRAPCVWLPGNHDFQPVMY
                     SALQEAGISPAKRVLIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERQTL
                     LLLHHHPLPAGCSWLDQHSLRNAGELDSVLANFPRVKYLLCGHIHQELDLDWNGRRLL
                     ASPSTCVQFKPHCANFTLDTIAPGWRTLELQANGVLETEVHRLQDTRFRPDTASEGY"
     gene            complement(16820..17242)
                     /locus_tag="OPV72_001777"
     CDS             complement(16820..17242)
                     /locus_tag="OPV72_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1249 family protein"
                     /protein_id="HCR9914105.1"
                     /translation="MKRYTPDFPEMMRLCETNFSQLRRLLPRNDAPGETVSYQVGNVQ
                     YRLTIVELTRYTTLVTIEQTAPAITYWSLPSLTVRLYHDAMVAEVCSSQQIFRFKARY
                     DYPNKKLHQRDEKHQINQFLADWLRFCLAHGAMAIPVY"
     gene            complement(17239..17871)
                     /gene="nudF"
                     /locus_tag="OPV72_001778"
     CDS             complement(17239..17871)
                     /gene="nudF"
                     /locus_tag="OPV72_001778"
                     /EC_number="3.6.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribose diphosphatase"
                     /protein_id="HCR9914106.1"
                     /translation="MRKSDNLPVTFTKSDVEIIARETRYRGFFSLDVYRFRHRLFNGE
                     MSGEVKREIFERGHAAVLLPFDPERDEVVLVEQIRIAAYDTSVTPWLLEMVAGMIEEG
                     ETIEAVARREAMEEAGLTVGRTRPVISYLASPGGTSERSSILVGEVDATTAVGIHGLA
                     DENEDIRVHVVSREQAYQWVEEGKIDNAAAVIALQWLQLHHQELKNEWKK"
     gene            18072..19547
                     /gene="tolC"
                     /locus_tag="OPV72_001779"
     CDS             18072..19547
                     /gene="tolC"
                     /locus_tag="OPV72_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462101.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane channel protein TolC"
                     /protein_id="HCR9914107.1"
                     /translation="MQMKKLLPILIGLSLSGFSTLSQAENLMQVYQQARLSNPELRKS
                     AADRDAAFEKINEARSPLLPQLGLGADYTYSNGYRDANGINSNETSASLQLTQTLFDM
                     SKWRGLTLQEKAAGIQDVTYQTDQQTLILNTANAYFKVLNAIDVLSYTQAQKEAIYRQ
                     LDQTTQRFNVGLVAITDVQNARAQYDTVLANEVTARNNLDNAVEELRQVTGNYYPELA
                     SLNVEHFKTDKPKAVNALLKEAENRNLSLLQARLSQDLAREQIRQAQDGHLPTLNLTA
                     STGISDTSYSGSKTNSAQYDDSNMGQNKIGLNFSLPLYQGGMVNSQVKQAQYNFVGAS
                     EQLESAHRSVVQTVRSSFNNINASISSINAYKQAVVSAQSSLDAMEAGYSVGTRTIVD
                     VLDATTTLYDAKQQLANARYTYLINQLNIKYALGTLNEQDLLALNSTLGKPIPTSPES
                     VAPETPEQDAAADGYNAHSAAPAVQPTAARANSNNGNPFRH"
     gene            19760..20431
                     /locus_tag="OPV72_001780"
     CDS             19760..20431
                     /locus_tag="OPV72_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1190 family protein"
                     /protein_id="HCR9914108.1"
                     /translation="MKRTKSIHHASFRKSWSARHLTPVALAVTAVFMLAGCEKSDETV
                     SLYQNADDCSAANPGKSAECTTAYNNALKEAERTAPKYATREDCVAEFGEGQCQQAPA
                     QAGMAPENQAQAQQSSGSFWMPLMAGYMMGRLMGGGAGFAQQPLFSSKNPASPAYGKY
                     TDAAGKNYGAAQPGRTMTVPKTAMAPKPATTTTVTRGGFGESVAKQSTMQRSAAGTST
                     RSMGG"
     gene            20437..21600
                     /locus_tag="OPV72_001781"
     CDS             20437..21600
                     /locus_tag="OPV72_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathionylspermidine synthase family protein"
                     /protein_id="HCR9914109.1"
                     /translation="MERVSITERPDWRDKATEYGFNFHTMYGEPYWCEDAYYKLTLAQ
                     VEKLEDVTAELHQMCLKVVERVIASDELMTKFRIPKHTWGFVRQSWQTQQPSLYSRLD
                     LAWDGIGEPKLLENNADTPTSLYEAAFFQWIWLEDQINAGNLPEGSDQFNSLQEKLIE
                     RFAELREQYGFQLLHLTCCRDTVEDRGTIQYLQDCAAEAEIATEFLYIDDIGLGEKGQ
                     FTDLQDQVIANLFKLYPWEFMLREMFSTKLEDAGVRWLEPAWKSIISNKALLPLLWEM
                     FPDHPNLLPAYFAEDEHPPMDKYVVKPIFSREGANVSIIENGKTIESVEGPYGEEGMI
                     VQQFYPLPKFGDSYTLIGSWLINDQPAGIGIREDRALITQDLSRFYPHIFVEG"
     gene            complement(21662..22450)
                     /gene="ygiD"
                     /locus_tag="OPV72_001782"
     CDS             complement(21662..22450)
                     /gene="ygiD"
                     /locus_tag="OPV72_001782"
                     /EC_number="1.13.11.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001356237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4,5-DOPA dioxygenase extradiol"
                     /protein_id="HCR9914110.1"
                     /translation="MSLTCMPALFLGHGSPMNVLDDNDYTRAWRRLGEALPRPQAIVV
                     VSAHWYTRGTGVTAMERPQTLHDFGGFPQALYDMHYPAPGSPALAQRLVELLAPVPVA
                     LDKEAWGFDHGSWGVLIKMYPNADIPMVQLSVDSTKPAAWHFEMGRKLATLRDEGVML
                     VASGNVVHNLRTVRWHGDNIPYPWAASFNDFVKANLTWQGPVEQHPLVNYLQHEGGAL
                     SNPTPEHFLPLLYVLGAWDGKEPITIPVDGIEMGSISMLSVQVG"
     gene            22591..23364
                     /gene="zupT"
                     /locus_tag="OPV72_001783"
     CDS             22591..23364
                     /gene="zupT"
                     /locus_tag="OPV72_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZupT"
                     /protein_id="HCR9914111.1"
                     /translation="MSVPLILTLLAGAATFIGAFLGVLGQKPSNRVLAFSLGFAAGIM
                     LLISLMEMLPAALDTEGMSPVLGYGMFIIGLLGYFGLDRLLPHAHPQDLVQKRQQPLP
                     GSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFGIALAVALHNIPEGLAVAGPV
                     YAATGSKRTAIFWAGISGMAEILGGVLAWLILGSLVSPIVMAAIMAAVAGIMVALSVD
                     ELMPLAKEIDPNNNPSYGVLCGMSIMGLSLVILQTIGIG"
BASE COUNT         5682 a         6596 c         5962 g         5420 t
ORIGIN      
        1 ctaaatcggc gcactgctgt gctaatttta tacgcacatt ggtacgccgc gtatcttctg
       61 gtggatacac cttatcgatc attgcgttaa gcttgttaca gtccaaccag gccatccggt
      121 aggcagtcat caggctatgc ctttcatcct ggtaatcaag gctggctaca ataagggctt
      181 ccgacaacgc cgtatgttgc tgttgcatac tttgcagtat ccccgccaga atatccggcg
      241 gcagcgcgtc ctctttcgag gctgtatgca atgtgcgtga aatcaggaaa ttccagccgt
      301 ccgtcaactt atcctgaggg atgtgctgcc agttcagcat ctgccctttc accaacgcac
      361 gcagcgtctc gccatccgca tcaataaaca gcgacgccag cagattttta ttcggataga
      421 ccgactgccc cagcacctgc ggcgtcagtt ttatctgggc aagcagcgct ttagtttgcc
      481 cctgcaacaa gaaataatat gcgcgataca gcggattttg cgcttcacgc cgctgccaga
      541 aaaaggccag tgtctcttta tcctgaagct gtatcgcccc cgaataggct tcatcggtga
      601 ggagatcggg catgacccgt agcagaatgt cggccatctc aaaaaaagtc tggcgaaatc
      661 cctcaggttt aaaacggggc gtggggagat actccaacgg attttgccgc cgtacgatgg
      721 tgcgatttgc ctgcgcctgc ggggagtcgc ccatgagctg ctcgctaaaa atacgcaccg
      781 cagtgatatt gccactctca aaagcagcaa aaaatggcgc attgacgaaa tagccatctt
      841 cccgcgagaa cctaaaaggc gatgccacac gtgcagtcag atcgcgcaag tttttttctg
      901 atatgcctgg cgcttttacc gcctgaacca gtgtctgttc caacgtactg ttatcatgaa
      961 tgctctctaa ctgacgcagg tcgcctgcct gaacctgcct gagcaactgc gcaatatttt
     1021 gctgttgcca ttgatagcta atagcacgcc acagctccgg catcaccggg cacagcatcc
     1081 caatgaacac aatatggcac agtagccatg cgggccacgg cttgcgcagc caggttccca
     1141 gcagcagcgc gggcagcaag cccgcccaac tcagaatcgg caacaggagc atcaacatcc
     1201 ataccgtgcc tgtttgactc aacaactggg tgtactgcaa cgtgggtaac agcaatacca
     1261 cgaatgccca ctgtggtagt aatacccaca gcaaaatctg tcggctgcgt tttttggaaa
     1321 acatcaggat cagcagtgat gccaccgcag cggcataccc ccacggtaga acacaaaaca
     1381 tcagcagttc agagccaagc catcgattaa tataatccat ttactattcc tttagtcact
     1441 tcgcgactgg acacagcgca ttcagccttt gtcgcgtatc gtgtagtact tgttcgctcc
     1501 ccactactaa agcattcaac acctcacgca attgctcaca ggaaagccca gcctgtaaaa
     1561 aagcggcagg aaacgtcggt gtccagggaa gatagtgggc gatttgctcg ttggataacg
     1621 ctttctgcgc ttgcatcgcc ttaatgatct gtatcagcaa tgcgttctct aatgctccac
     1681 cacgcagtcg taatatggcc tgatgcagag gctcattatt tccgtcttcc attgctcgtt
     1741 tccagtccac tacgtttgca tcaataagcg actgaatcat taccagatcg ccattgctca
     1801 gtatgaaagt gagtaggttt tcacgatccc acctctcaat cggcggtgtg atcaatattt
     1861 ctggattatg ggttacctcg cttattagcg attccgtttt ggctaacaac accatcgctt
     1921 cgagcctgcg cagaggaata gtgggagggt gtttctgcca aaaataagca accaactcag
     1981 tgttacgttg gataatggga taaatataga cagtatcatt caacagttct ggcataatat
     2041 tcagcaatag ctgactaatt tctagtctgt actgctcgcg atactgtgat atatagttag
     2101 atttataaag cgtcagcagt ggattttctt tacgagcaac aatattgcga ttctctctgg
     2161 cggaagatgt ctcgcccacc agttgctggc taaaaaagcg tactatcggt acgttatgtt
     2221 ggcgaagagc ggtagcaaat ggcgtataaa gaaattcggc gttcgggatc gccgcttcag
     2281 ggcaagattc tgccgctgtc aaaaatggcg aaatacctcg tattttagcc agataacgca
     2341 ataaattttc cggtgtatcg cggtgttctg cagccagcgt caaaacactt gccaattgat
     2401 aacaagatgc atcctgcaaa acctgaacat cccccttcgc gcgctcaaac agtcgggtaa
     2461 ttttatagtt atctcagtct tcaccaatgt ggtgccataa tcgcgggccg tccatcacat
     2521 aaacgaaaac gaacaaaaaa atagtatggg acacgatagt tcccagtata aaaaatggag
     2581 actctcgact agaaaaaata gcaattatta tcgagggcag caatcctgat atcaataaat
     2641 atacgatata aatatctttt gaatcaatcc agaataatcc tccccacact acacagacaa
     2701 cgctcacctg cggaagaaca acacgcaaga aaacccgccg atagcgcaaa gaatcaaatg
     2761 cgccgacaat taacctcaat aatacaacgc cataaatacc ccacgcgctc atcaatatta
     2821 ctgaatccca catcatccac gcaaatgatt cacccataaa gtatccttac tttccatgct
     2881 cattactgag ttcaaattcc tcgttcctat tttccgataa cacagcgagc taaacgcact
     2941 aataactata gtaaatacaa tgattgtata tattgcccgg cacggaggat attatcatca
     3001 acaacaaact ccatccgttt cccaaattca ttattgcccg ctattttttc tgatgataaa
     3061 acacatcaaa ttcaaactgc catgagaaag gttccggttt gttgctatta tcaaaggcaa
     3121 cggcttgtgc atacagttcg tccgtcaata attccggcac gacgctaatc aaactggtac
     3181 aaatatctcg cgccaaaagt tgttgttgca gaaaagtttg ttcatcagcc gtactatcat
     3241 taaaaacacg attcagtagg tccaataatg gattgttttg taagagctga tgccgatatt
     3301 gctttgcctg tacagaatcg ccaataaacc aggaggcaaa cgtcccaaca gcagaacgat
     3361 taagccggtc gatggccaaa accaaccaaa ttttttcagt tccgcccgca atatcaaaag
     3421 gggaaatgcg ttttgcgaga tgctcaatcc gcctattcgt cccccaatcc cctgcgtttt
     3481 gcggctgcat ggcttgcgac atcaaatgat ttaaaaaaac gcggtcatca gtcgtatcga
     3541 tttttcgtaa cagcgtttct tccgccacct gctgtgcctg ataggcatcg cgccgatgat
     3601 gcctatcgag aatatccccc atgtgcgcca acaacagcag caatacgacc acatagcacc
     3661 cggcccaaag gtggtgtggt tggcgtaatc ggtggctaaa cagtagcgcc aacaataaac
     3721 taagccccag catccaccct gcactaatcg gaaagaaaag cgtttcatca tccgcagcaa
     3781 accatagcaa aagaaccagc gcaatctatg gcaaagcaat ccacagcaac acgcgacgag
     3841 gcgtttggaa caaaaaagcc aggcaaataa caacgaagag cagaataaga tagccgcctg
     3901 tagtaaacat ccagaacgtc agtagccgcc atccctcttc attgattctc atcgaatatc
     3961 cctggttcgc ctttacgacg ccggattcac cagcatttgc ccaatcgagc cgcgatcagc
     4021 catttccagc gtctggctgt tgaaatagaa cgggaagtgc ggccaggacg gctgaccgta
     4081 gtagaccagc aattcgactt gcccatccac ccagacggta tctttccagc ctctatcttc
     4141 cgggaacggc atagcgccgt tgacgttacg aatcaggaaa gagacgccct caatatggaa
     4201 cgactgcggc atatcggcgc gtaccgtcca gcgctcccag gtgccttgtt gggcggtaat
     4261 atcaatgcga ttcacatccc acagttggcc gttaatcccc ggatcgtcgc caagactgat
     4321 gtcccgactg cggacaggcg caccgctcat gatctccgtc ggcaacagac gcatcggcag
     4381 attatcggtc accagcggca gcaatccggt tggccgtaac gtcagcacca gggtcgaaac
     4441 cagaatactg gaaggctcaa agaaaccgcg aatccgatcg actatgctgg ccgcttcccc
     4501 gcaggtgatc gagacttcgt cgccgttggt catatcaacc aggatttcac gtcgctcgcc
     4561 gggcgccagt gacaactgtt tgacggaaac cggcgcaggt aaaaagccct gatcgcctga
     4621 aatcacatgc agcgcccggc catcgctcat ctgaagctga tagcgccgcg agttcgaggc
     4681 gttcaacaac cgtaaccgca cccagccgcg ggacacttcg acataggggc tttgcgcgcc
     4741 gttcaccagc agcgtatcgc cgacaaaacc accgctgccc ggttcgctgt actccggcgt
     4801 cccaaagtta tccagccgtt tatcctggat aataacggga aaatcatcca cgccgtaatg
     4861 gttcggaatg ggcagcgttt tactgatgtc atcttcgacc agccacattc cggccaggcc
     4921 gttatacacc tgctgcgcag tgcggttagg cgtgttagcg tgataccaca gcgtcgcggc
     4981 gctctgacga atcggcaaca ccggcgccca gtccgcgttc ggcgacatca tacgcgccgg
     5041 gccacccatc agcggccccg gcaccagtaa accagcaacc gtcatggaga cattttccgc
     5101 caggcggttg ctatagatga gtttaacgtc atcgcctttc cagacgcgga ttgtcggccc
     5161 cagataacga ccgttcactc cccagaccgg cgcgcgcgtg ccttgcgtaa aggaccagtg
     5221 cgctcgctgt agcgtcataa acaacggctg cccgcgacgg gactccagca acggcggaac
     5281 aggcaacggc tgttgctgac cggcagcatt cgccctgagg ggaatcgcgc ctgcacatag
     5341 tgcgattccc gatgcctgaa gaaactgacg ccgactgaat gacatataag ctccatgtaa
     5401 aacaggctaa agagttgtgc ctgaaaaaat gatttctaca ataacagagt aaggctgctt
     5461 aaaccttacc ggtcgcttca cgttccgcaa cctctttatc aagttccgcg attttttgct
     5521 ccattaacgc acggcagtgg gccgccagct cacgaacctg atctttacca tattcgctga
     5581 cgtcgactgg cggcagcatt tccacaataa ccagtccgtt gttcaggcgg tttagattga
     5641 ctttgttaga ggtgttggaa acgcagacag gaatgatcgg cacaccagcc gcgatagccg
     5701 catgaaacgc gccggtttta aacggcagca gaccgcgtcc ccggctacgc gtaccttcag
     5761 ggaacatcca gatagaaata cggcgctttt taaaatggtt aactactgcc gcaatggtgc
     5821 tatgcgcttt ggcgcggtta ttacggtcaa tcaacagatt accggtcagc cagtacagtt
     5881 gcccaaaaaa cgggatccaa agcaggcttt ttttccccac cgtcaccgtt ggcggctgca
     5941 caatattcgc cgccgtgacc atatcataat tattctgatg gttagcaata tagatagcat
     6001 tgccatagtt ttccgcatcg gcgggtttgc ggcactccac tttcaggcca aacagcgggg
     6061 ccagacgacc gaacatatgt ccaaacgtcg ccacgtgttt tgggttacgt gggctgaaaa
     6121 ggcagtaaat agaaccgaaa acacagacca gaatggagta aataacggta acaataagac
     6181 gaaaaatata tagcataaca acctctgaag gcctaagagc ccggcattct acgtcacctg
     6241 aaattcaggt taggattttg gtaagtgtgg ctctctggaa aaacgtattg ttaatcgcaa
     6301 tgcacgaata aacaacggtt ttacgggaaa ttttaatgtt aatccgatct gaaaccgtag
     6361 gccggataag acgctactgc gtcgtcatcc ggcaacggca gagcgccgga tggcggctta
     6421 gatgccttgt ccggcctacg ggcgcccctg tcttactctt cgctgtcgcc atgacttacg
     6481 cgatgcggcg aatcaatctc aatgcgatcg atacgctgca ggccgcgcat taatgtgcca
     6541 cggcgtccgc gttcaccgac caccttttgt aactcttcag ggcgcagttt gattttgcgc
     6601 ttcccgacat ggatagtcag agtgctttgt ggcggcagca cgtacaggtg cgccagtcca
     6661 tcatcgcctt tcgccgcttc cgcagagggg atattaatga tcttattgcc tttgcctttc
     6721 gacagctgcg gcagagagtc taccgggaac atcaacatcc gtccggcctg ggtaatcgcc
     6781 agcagcatat cgtgctcgtc tttaatcacc agcggcggca tgacgtgcgc attttccggc
     6841 agtgtaatca acgtcttacc ggcacggtta cgggcaacca gatcgttaaa cgtacaaacg
     6901 aagccgtagc ccgcatccga cgccatcagc agtttctggt catcgccttc catcagcata
     6961 tgctctacgg tcgcccccgg cggcagcgtg agtttgccgg tcagcggctc gccctgccca
     7021 cgcgccgagg gaagcgtaat gggatcaata gcatagctgc gcccggtggt atcaataaac
     7081 accaccggtt gattgctctt acctttcacc gcggctttaa agctgtcgcc cgctttatag
     7141 ttaagccccg gcgcatcaat atcatgacct ttggcgctgc gcacccagcc catctgcgac
     7201 agcacgatag tcaccggttc ggacggcagc atatcgtgtt cgctcatcgc tttagcttct
     7261 tcgcgctcac gcagcggaga acggcgatcg tcgccatagg catcggaatc tgcctgtagc
     7321 tcttttttca gcaaggtatt cattttgcgt tcggacgcga gaatgccctg caactggtca
     7381 cgctcttttt ccagctcgtc ctgctcaccg cgaattttca tctcttccag tttggcgaga
     7441 tgacgcagtt tcagttcgag aatcgcttcc gcctgggttt cgctgatgcc gaaacgcgac
     7501 atcagcgcgg gtttcggctc atcctcgtta cggataatct cgatcacttc atcgatgttg
     7561 agaaacgcca ccagcaaacc ttcgaggata tgcaggcgct taagcacttt ctccagacga
     7621 tagttcagac gacggcgcac cgtgtcgcgg cggaacgcca gccactcggt gaggatctcc
     7681 agcaggtttt tcaccgccgg acgaccatcc agaccgatca tgttcaggtt aatacggtag
     7741 cttttttcca gatcggtggt ggcgaacaga tggttcatca cctgttccat atccacacgg
     7801 ttggagcgtg gcacaatcac taaacgcgtc gggttttcgt gatccgattc atcgcgcagg
     7861 tcgtccacca tcggcagttt tttattgcgc atctgcgcag caatctgctc cagcactttt
     7921 gcgccagata cctgatgcgg caacgcggtg atcaccacgg cgccgtcttc tttggtccat
     7981 accgcgcgca tacgcacgga gccacgccca ttttcgtaaa ttttacgaat ttccgcacga
     8041 gggataatga tctccgcttc ggtcgggtaa tccggcccct ggacgatatc cagcaactga
     8101 tccagcgtcg ttttcggctg ctcaatcagc gtaatcgccg ctttcgcgac ttcgcgcagg
     8161 ttatgcggcg gaatatctgt tgccatgccc accgcaatac cggtggtgcc gttcagcagg
     8221 atgttcggca gacgcgccgg taacattttc ggttcctgca tggtgccgtc gaagtttggc
     8281 acccagtccg cagtcccctg accgagttcg cttaacagca gctcggcgta tttggacagg
     8341 cgggattcgg tataacgcat cgccgcgaat gacttcggat catccggcgc gccccaattc
     8401 ccctggccat cgaccagcgg gtaacggtaa gagaacggct gcgccatcag caccatggct
     8461 tcatagcagg cgctgtcgcc atgcgggtga tacttaccca gtacgtcgcc aacggtacgg
     8521 gcggattttt taaatttagc ggtggcgttc agccccagct ctgacatcgc atagacgatg
     8581 cggcgctgta ccggcttcag gccgtcgcca ataaacggca acgcacgatc catgatcacg
     8641 tacatggagt agtttaagta ggcgttttcc gtaaattcat gtagcgcaag gcgctctgcc
     8701 atatcgctca ttaacagggg atcctcaatc tgcatgctga ccgttcggac ggcaatattg
     8761 ccgcagataa taccctatct cacggtctga gtcacaaacc gtgagacagg ttgcgaggaa
     8821 gttaacgaag cggcagatag atatccgtca gcagctcatg ttccgccacc tcatggacga
     8881 aattcaggta ctggaagaag accggaaaat cgcgcagcgt ctcgccgctg gccggtagcc
     8941 attcgcggaa taaataccac acgctctccg ggaggctgtc gagcgatccc tgatggcgca
     9001 ccaccgcgca gcgcccgcca ggaatctcgc tattcaccac gccaacgtca ttttcggcta
     9061 tcggctggcg gacgctgccg cagatatcaa agcggaattg agccggcggc gtcgtctgcg
     9121 ggtcgtgcca ggcaatacca aaagtttgac tgctggcaat cggcgactgg cccgtttcgc
     9181 gtcgccatgc aataaatttc gccgcgctgg cgttgacctt atccggatgc cccagatgcg
     9241 tcagcatcgc gacgcgggta ggaggaaatt caacgatttt tacgtccatg acatgctgct
     9301 cctgtaacgc aagtttagga acgcgttggt gccaggccag ccagtccggc gattgccgaa
     9361 accggcacgg gctttgacca aacgcggttt tgaaagcacg tgtgaacgac tccggattct
     9421 gaaatccggc atccagcgcg atatcgataa ctttatcttg cggattaaac gccagccgcc
     9481 atgacgcccg gcgcaaacgc agccactgga tatagcgata gagcggaagc ccgctccaga
     9541 cggtaaactg ccggtgaaaa tgaaacggcg agctgtgcgc catccggctt aacgcctcaa
     9601 gcgacagagg ctcatccaga tgacgctcaa tgtggtcgca aacgcgccgc agacgttcgg
     9661 aataagccgc gctgatcagg tcattcatca ctgcctcctt gtggcctatt ctgcccaccg
     9721 ggcggctgtg aatcctgacc gatcttgcgc aatgtgggat tacggattca ctttacgaat
     9781 ctgtttcacg tcgatttcga cagagttcca gtctttatcc acttcaccct gaatttcaac
     9841 ggtatcctgc ggggttacgg tcaggccgtt ccagcgcttg tggtcaatgt ccacattgat
     9901 agtaccggtc gcatctttaa acacatacag gtcgtcggaa atgcgctcga cgatattccc
     9961 gcgcagcgtt acccacgcat cgtcacgcag cgatttagcg ctctctaccg tcgtgctgct
    10021 gccgttcggg ccgacaaatc cgccgccctg cgtttgcgtc gccgacgggc cggagaaacc
    10081 gccctgctga gccgccagaa ccggggtaga acacagtgcc ataacggcaa cgattgcagc
    10141 taattttttc atgattactt ttccctttca tgtcgtttca gatccattta ataaggtaat
    10201 ccttaacaac ttcttaaggc aaaaaaagat tctttttttc tgtacatcgc ctgcggcgac
    10261 aaggttaact gacggcaacg cgagttaccg cagggaagaa cagatgcgaa ttttactggt
    10321 agaagatgac acacttattg gcgatggcat aaaagcaggt ctgagtaaaa tgggtttcag
    10381 cgtcgactgg tttaccgagg gacgtccggg caaagaggcg ctttacagcg cgccttatga
    10441 tgcggtcatt ttagatttaa cgctgccagg aatggacgga cgggatattt tgcgcgaatg
    10501 gcgcgaaaag ggtaaacagg aaccagtact gatcctgacg gcgcgcgacg cgttagcaga
    10561 gcgcgtcgag gggctacgtc tgggcgccga tgactattta tgtaaacctt tcgcgctcat
    10621 tgaggtcgcc gcccgtctgg aggcgctggt acgccgcgcc agcggtcagg ccagtagcga
    10681 attgcgccac ggccaggtga cgctcaatcc aggcaatctc gtcgcgacgc ttgccggcga
    10741 accgctggcc ctaaaaccaa aagagttcgc gttgctggaa ctcttactgc gcaacaaagg
    10801 tcgcgtgcta ccgcgcaagc ttattgaaga gaagctgtat aactgggatg acgacgtgtc
    10861 cagcaatgca gtggaagtcc atgttcatca tttacgccgc aagctcggca gcgaatttat
    10921 tcgcaccgta cacggcatcg gctacaccct gggtgacgca tgaaattgac gcaacgtctc
    10981 agcctgcgcg tcaggctgac gcttattttc ctgattctgg tctccatcac ctgggcaatt
    11041 tccagttttg tggcctggag aaagacgacg gataatgtcg atgagctgtt tgacacacag
    11101 ttgatgttgt tcgccagacg gcttagcacc ctcgatctta acgagctcaa cgccccgcag
    11161 cgcatggcgc atacgccaaa gaaattaaaa catgggcata tcgatgacga tgcgctggcg
    11221 ttcgccatct tttccgctga cggcaaaatg ttgctgcatg atggcgacaa cggccaggat
    11281 attccgtatc gctatcgccg ggaaggtttc gacaatggct atctgaagga tgacaacgac
    11341 ctctggcgtt ttttgtggtt gaactcggcg gacggcaagt atcgtatcgt cgtcggtcag
    11401 gagtgggatt accgcgaaga tatggcgctg gcgatcgtgg cggcgcaatt aacgccgtgg
    11461 ctgatcgccc ttcccttcat gctgctgatt ttattactcc tgcttcaccg cgagctcaga
    11521 ccgttgaaaa aactggcgca ggcgctgcgc ttccggtcgc cggaatcgga aacgccgctc
    11581 gacgccaaag gcgtaccgag cgaggttcgc ccactggtcg aagcgcttaa tcagcttttt
    11641 agccgcatcc actccatgat ggtgcgcgaa cggcgattta cctccgacgc cgcccatgaa
    11701 ttgcgcagcc cgctggccgc gctgaaagta caaaccgagg tggcgcagct ctcgggcgac
    11761 gatccgctat cgcgtgataa agcgctgacc cagctccatg cggggatcga tcgcgccacg
    11821 cggctggtcg atcagctact gacgttatcg cgtctcgact cgctcaataa tttgcaggat
    11881 gtagcggaga tttcgctgga agagctgctg cagtccgcgg taatggatat ttatcatccg
    11941 gcgcagcagg cgaatatcga cgtgcgttta cagcttaacg cccatgacgt catacgtacc
    12001 ggccagccgc tactcttaag cctgttagtg cgtaacctgc tggataatgc gattcgctac
    12061 agtccgcagg gcagcgtcgt cgacgttacc ttacatgccc gcagcttcac cgtcagagat
    12121 aatggccccg gcgtagcgcc agagattcta acgcatatcg gcgagcgttt ttaccgcccg
    12181 ccaggccaaa gtgtgaccgg cagcggtctg ggattatcaa tcgtccgccg catcgctacg
    12241 ctgcacggca tgacggtgtc gtttggcaac gccgcggaag gtggatttga ggccgtagta
    12301 cgctggtagc agagattttt gccaaaaacg caaaagactt tgcacatttt gctaatttca
    12361 ccgcaccgcc cgtcagcgta gaatcagcag caaacgcatt tcttgaggac acaaaatgag
    12421 taacatcctg attatcaacg gggcgaaaaa attcgcgcac tccaacggcc agttgaatga
    12481 caccctgacc gaagttgccg atgggctgct gcgcgatctg ggtcatcagg ttaagatcgt
    12541 ccgcgccgac agcgactatg acattaaaga agaggtgcag aatttcgtct gggctgacgt
    12601 ggtgatttgg cagatgccag gctggtggat gggcgcgcca tggacagtaa aaaatatatg
    12661 gatgatgtct ttaccgaagg tcacggcacg ctctatgcca gcgatggccg cacgcgttcc
    12721 gatgccgcta aaaagtacgg ttccggcggt ctggtgcagg ggaaaaaata tatgctgtca
    12781 ctgacgtgga acgcgccgat ggaagcattt accgaaaaag atcagttttt ccacggcgta
    12841 ggcgtagatg gcgtctatct gccattccat aaagccaacc agttcctggg catggacgcg
    12901 ctgccaacgt ttattgccaa cgacgtgatt aaaatgccgg atgttccgcg ctataccgca
    12961 gaatatcgca agcatcttag cgaaattttt gcttaactgg tcatcctgga attagaagga
    13021 gttaaccatg cttaccgtca ttgccgaaat tcgcacgcgt ccgggccaac atcaccgtca
    13081 ggccgtcctc gatcagtttg cgaaaattat tccaaccgtt cttaaagaag aggggtgcca
    13141 cggttacgcg ccgatggtgg atcatgccgc gggcgtgagt tttcagactc tggcgcctga
    13201 ctcgatcgtg atgattgaac agtgggaaag cgttgcgcac cttgaagcgc atctgcaaac
    13261 cccgcatatg aaagcctata gcgacgcggt aaaagacgat gtgctggaaa tgaatattcg
    13321 tattctggaa tccggcgttt aagttattac cctcgtctga cgtcgccctg atgcgatgcg
    13381 caagtgtcgc catcaggctg cgacgtcatg tcggattctc ttatccggcc tgcggcgcgc
    13441 agaccggata aagcgtgcaa caatcgttac acgtcgagat ccgcgagatc gcctttttcc
    13501 tgtagccagt tgcgtcgatc ttcagaacgt ttcttcgcca gcagcatatc catcatcgca
    13561 ttagtacgct gatcgtcttc atcgctaatg gtgagctgca ccaggcggcg agtattcgga
    13621 tcaagcgtgg tttcgcgtaa ctgcatcggg ttcatttcac ccaggccttt gaaacgctgg
    13681 acgttcggct tgcctttctt acgcttcagt tgttccagta cgcccgcctt ctcttcttcc
    13741 gtcagcgcgt aatagacctc tttacccaaa tcgatacggt atagcggcgg tagcgcgacg
    13801 tagacatgac cattcttcac cagcgcgcgg aagtgtctga caaacagcgc gcaaagcaga
    13861 gtagcgatat gcaaaccatc ggagtccgca tccgccagga tacagatctt gccgtagcgc
    13921 agctgactca gatcgtcgct gtccggatcg ataccgatcg ccacggaaat atcatgcacc
    13981 tcttgcgagg ccagcacttc atcggaagag acttcccagg tgttaaggat cttacctttg
    14041 agcggcatga tcgcctgata ttcgcgatcg cgcgcctgct tggcggaacc gcctgccgaa
    14101 tccccttcca caaggaacag ctcggttcga ttaagatcct gcgcggtaca gtccgccagt
    14161 ttccccggca acgccggacc gctggtgagt tttttgcgta ccactttttt tgcggcgcgc
    14221 agtcgccgct gcgcgctggc aatcgccatc tctgccagtt gttccgccgc ctgcacgttc
    14281 tggttcagcc acaggctgaa ggcatctttc accacgccgg aaacaaatgc cgcacattga
    14341 cgcgacgaca gacgctcttt ggtctgcccg gcaaattgcg ggtcctgcat tttcacggag
    14401 agcacataag cgcagcgatc ccagatatct tccgccgaca gtttgacgcc gcgcggcaga
    14461 atattgcggt attcgcaaaa ttcgcgcatc gcgtcgagca ggccctggcg cagaccgttg
    14521 acgtgcgtcc ccccctgcat ggtcgggatc aggttgacgt agctttccgt cagtaattcg
    14581 ccgccttccg gcagccacaa tagcgcccag tcaaccgctt ccgtttcacc gttaaaatta
    14641 ccgataaacg gcttttccgg cagcgtcggc aggccgttta ccgcttcgcc cagatagtcg
    14701 ttcagaccat cctggtagca ccagcgctgc tcgctgttat tcacttcatc tttaaaagtg
    14761 atttccacgc cgggacacag caccgctttt gctttcagaa cgtgcattaa gcgagagaca
    14821 gaaaaacgcg ggctgtcgaa gaaactttcg tccggccaga aatggacgct ggtgccagta
    14881 ttacgtttac cgcaggtgcc gacaacctgc aaatcctgca ctttttcgcc gttttcaaac
    14941 gcgatgttat agacctgacc gtcgcggcgc acggtcactt ccacgcgctt tgacagggca
    15001 ttcacgaccg aaatccccac cccatgcaga ccaccagaga actgatagtt cttattggag
    15061 aatttaccgc cggcatgaag ccgacagagg atcagttcta ccgccggaac cccctcttcc
    15121 ggatggatat ccaccggcat cccgcgtccg tcgtcaatca cttccagcga ttgatcggca
    15181 tgtaaaatga catccacgcg tttggcgtga cctgccagtg cttcatccac actattatca
    15241 attacttcct gacccaaatg gttggggcgg gtcgtatcgg tgtacatccc cgggcggcgg
    15301 cgtaccggct caagcccagt gagtacctca atggcatcag cgttataagt ttgcgtcatg
    15361 gtttaattag caattcgaat tgattgtcag caactgtgca gtccaagaaa atcgacaatc
    15421 tggttgaaat aatcttcgaa gcccgtgaat gcgtgattac ccccctcggt cactgtctga
    15481 cggcaggagg cgtaatatgc caccgcctgg cggtaatcca gcacttcatc gcccgtctgt
    15541 tgcagtagcc agatcaggtc cggcgcttcc agcgggtcaa tctgcatgac tttaagatca
    15601 taaatatggc gagactctag cacatattgc tgcccggtgt aggggttctc gttctgaccg
    15661 agatagtcgg tcagtaattc aaagggccgc acggcgggat tcaccaccac agccggcagc
    15721 ataaaacatt gcgacagcca ggtggcgtaa taaccaccca gcgacgatcc taccagccct
    15781 aatggcgcac cgccatgctc aagtacgaga gattccagca actccgccgc atcggcagga
    15841 tacggcggca gttgagggac gatcatctca acatgcggat gacgctccgc cagccagttt
    15901 tttagctggc acgcttttgc cgagcgaggg gaactgttga atccgtgcaa atagagaagc
    15961 gtagacatca gtatccttcc gaagcggtat cgggtcggaa ccgggtatcc tgcaggcgat
    16021 gcacttccgt ctccaggacg ccgttcgcct ggagctccag cgtacgccag cccggcgcga
    16081 tagtatccag cgtaaagttc gcgcagtgcg gtttgaactg tacgcaggtt gacggcgacg
    16141 ccaacagacg gcgaccgttc cagtcgagat ccagctcctg gtgaatatgt ccgcatagca
    16201 gatactttac acgcgggaaa ttcgccagca cgctatccag ctcaccagca ttacgcaagc
    16261 tgtgctgatc cagccaactg caccctgccg gcaacggatg gtggtgcaac aggagcaatg
    16321 tctgtctctc tggcgcatcg gcgagcttac gctcaagcca ttccagttgg aactcgctca
    16381 gttcgccatg cgggacgcca aacacctggc tatccagcaa caaaatctgc cattgttcac
    16441 cgattaacac gcgtttagcc ggggaaatcc ccgcctcttg cagcgcgctg tacattaccg
    16501 gctgaaaatc gtgattgccc ggtagccaaa cgcaaggcgc gcgaaagctt gcgataccct
    16561 cagcaaaatg ctgataagcc gcagcggatt gatcctgcgc cagatcgccg gtcgccacga
    16621 tcagatcata ttcatactgt tgcgcccgaa tagcctccag cacggcctgg taactttccc
    16681 aggtattgac gcctaacagc gtttcatgct tttcggcaaa caggtgagta tctgtaattt
    16741 gtaaaatcct gactcgggcc tcaccagcca gaggtagggt taacaggctt tccaaatggt
    16801 gtccttaggt ttcacgacgc taataaaccg gaatcgccat cgctccatgt gctaaacaga
    16861 atcgtagcca gtcggccaga aactgattaa tttgatgctt ttcgtcgcgt tgatgcaact
    16921 ttttatttgg ataatcatac cgcgctttga agcgaaagat ctgctggctt gaacacactt
    16981 cagccaccat cgcatcatgg tagaggcgca ccgtcagcga cggcaggctc cagtaggtga
    17041 tggctggcgc cgtttgctcg atcgttacaa gcgtagtgta tcgggtcaat tccacaatcg
    17101 ttaaccgata ttgtacgttg cccacctgat agctcaccgt ttcaccgggg gcgtcattgc
    17161 gcggcagcag gcggcgcaat tgcgaaaaat tggtttcgca caaacgcatc atttctggga
    17221 agtcaggtgt ataacgcttc attttttcca ctcgtttttt aactcttgat gatgcaactg
    17281 aagccattgc aaagcgatga ctgcggctgc gttgtcgatt ttcccctctt ctacccactg
    17341 gtatgcctgt tcccggctta ccacatgaac ccgaatatct tcgttttcat ccgccagacc
    17401 atgaatacct accgcggtcg tggcgtccac ttcacccacc agaatagatg agcgctcgct
    17461 ggttcctcct ggactcgcca ggtaactgat gaccggtcgg gtgcggccta cggtcagccc
    17521 cgcttcttcc atcgcctccc gccgggcgac cgcctcaatg gtttcgcctt cttctatcat
    17581 gccggcgacc atctccagca gccacggcgt aacgcttgtg tcatatgcgg caatacgaat
    17641 ctgttcgacc agcaccacct cgtcgcgttc agggtcaaag ggtagcaaga cggcggcgtg
    17701 cccgcgctca aaaatttcgc gctttacctc gccactcatt tctccgttga ataaacgatg
    17761 gcggaatcga tacacatcca atgaaaaaaa accgcgatag cgcgtttccc gtgcaataat
    17821 ttctacatcg cttttggtga aagtaactgg caagttgtct gatttacgca ttgtgctgcc
    17881 ctgctagcaa taatgattaa atgatgaatt tcaagggtgg ttgactgctg ttttatcacc
    17941 cttgtggtaa attggtgcca attaaggctc gtatggcacg taacgccaac tttttgcagt
    18001 ggcggattct gctagaatca gcaattattt ttacaaattg atcagcgcta aatactgctt
    18061 cacaacaagg aatgcaaatg aagaaattgc tccccatcct tatcggcctg agcctgtcgg
    18121 ggttcagcac actaagccag gcagagaacc tgatgcaagt ttatcagcaa gcacgcctga
    18181 gcaacccgga attgcgtaaa tccgctgccg atcgcgatgc tgcattcgaa aaaattaacg
    18241 aagcacgtag tcctttactg ccgcaactgg gtttaggtgc cgactacacc tacagcaacg
    18301 gttatcgcga tgcgaacggt atcaactcca atgaaaccag cgcttctctg caattaacgc
    18361 agacgctatt tgatatgtcg aaatggcgtg ggctcaccct gcaagaaaaa gcagcaggca
    18421 ttcaggatgt cacctatcag accgatcagc agacgctgat cctcaatacc gcgaacgcgt
    18481 attttaaggt attgaacgct attgatgtgc tttcctatac ccaggcgcaa aaagaggcta
    18541 tctaccgtca gttagatcaa acgacgcaac gttttaacgt gggtctggtc gccattaccg
    18601 acgtgcaaaa cgcccgtgcg caatatgata ccgtactggc gaatgaagtg accgcccgca
    18661 acaacctgga taacgcggta gaagagctgc gccaggtaac cggcaattat tacccggagc
    18721 tggcgtcgct taacgtcgag cattttaaaa ccgacaaacc caaagctgtt aatgcgctgc
    18781 tgaaggaagc ggaaaaccgt aacctgtcgc tgttgcaggc gcgtttaagt caggatctgg
    18841 cgcgcgagca aatccgtcag gcgcaggatg gtcatctgcc gacgctgaat ttaacggcct
    18901 caaccggcat ttctgatacc tcttatagcg gttctaaaac caactccgcc cagtacgacg
    18961 atagcaacat ggggcagaat aaaatcggcc tgaacttctc cctgccgctg tatcaaggcg
    19021 ggatggttaa ctcgcaggta aaacaggcgc agtataactt cgtcggcgca agcgaacagc
    19081 tggaaagcgc gcaccgtagc gtggtgcaga ccgtacgttc ttcctttaac aatattaacg
    19141 cctccatcag cagcatcaac gcgtataaac aggcagtcgt ttccgcgcaa agttctttgg
    19201 atgcaatgga agccggttac tcggtcggta cacgtaccat tgttgacgta ctggatgcca
    19261 ccaccactct gtatgatgcc aagcagcaac tggccaacgc gcgttatacc tatttgatta
    19321 atcagttaaa tatcaaatat gcgctcggta cgctgaacga gcaggatctg ctcgcgctta
    19381 acagtacgtt gggtaaacct atcccgacgt cgccggaaag cgtagcgccg gaaacgccag
    19441 agcaggatgc tgccgcagac ggttataatg cccatagcgc cgcgccggca gtacagccga
    19501 ccgccgctcg cgccaacagc aataacggca atccattccg gcattgataa gttattcgct
    19561 ggcgctgcgt ttatcagacc tatgcccttg taggtctggt aagcgcggcg ctacctgtca
    19621 taaagccgcg cctgaacgta agacaacgta aagatcctgc tattccgccg cattctcgcc
    19681 ttttctcgct tcaatttcga ccagtcatcc tctattctga acgcatgttg tatttaccac
    19741 tgggtcctgg aagacaaata tgaaacggac aaaatccatc catcacgcat catttcgcaa
    19801 aagctggagc gcgcggcatt taacgccggt cgccctggcg gttacggctg tttttatgct
    19861 ggctggctgt gaaaaaagcg atgaaaccgt atcgctgtat caaaacgctg atgactgttc
    19921 agcggcgaat ccgggcaaaa gcgcggaatg tacaaccgcg tataacaatg cgctgaaaga
    19981 ggccgaacgt actgcgccta agtacgctac acgcgaagat tgcgtcgctg agtttggcga
    20041 aggccagtgc cagcaagcgc ccgcacaggc tggcatggcg ccggaaaatc aggcgcaggc
    20101 ccaacaatcc agcggcagtt tctggatgcc gcttatggca ggttacatga tggggcgtct
    20161 gatgggcggc ggcgcaggct ttgcgcaaca gccgctgttt agctcgaaaa acccggccag
    20221 ccctgcatac ggcaaatata ccgatgcggc aggtaaaaac tacggggcgg cgcaaccggg
    20281 ccggacaatg accgtaccga aaaccgcgat ggcgccgaaa cctgccacca caacaaccgt
    20341 tacccgcggc ggttttggcg aatccgtcgc caaacagagc actatgcagc gtagcgctgc
    20401 cggtacttca acacgttcga tgggcggctg atacgcatgg aaagagtcag tattaccgag
    20461 cgcccggact ggcgcgataa agcgactgaa tacgggttta attttcacac tatgtatggt
    20521 gaaccgtact ggtgtgaaga cgcttattac aagttaacgc tcgcccaggt ggaaaaactg
    20581 gaagacgtta ccgccgagct gcaccagatg tgcctcaagg tagtagaacg cgtcatcgcc
    20641 agcgatgagc tgatgacgaa gtttcgtatt ccaaaacata cctggggttt tgttcgccag
    20701 tcctggcaaa cgcaacaacc gtcactctat tcccgcctcg atttggcctg ggacggcatc
    20761 ggcgagccta agctgctcga aaataatgcc gacacgccaa catcgctgta tgaagcggcg
    20821 ttttttcagt ggatttggct ggaagatcag atcaacgcgg gcaatctgcc ggaaggcagc
    20881 gatcagttta atagcctgca ggaaaagctg attgaacgct ttgctgaact tcgcgaacag
    20941 tacggttttc agttgctgca tctcacctgc tgtcgcgata cggttgagga tcgcggcacc
    21001 attcagtatt tacaggattg cgcggccgaa gcggaaatcg ccaccgaatt tctctatatc
    21061 gacgatattg gtctggggga aaaaggtcaa tttacggatc tgcaggatca ggtcattgcg
    21121 aacctgttca agctctatcc gtgggaattt atgctacgcg agatgttttc caccaagctg
    21181 gaagatgccg gcgtgcgctg gctggaaccg gcctggaaaa gcattatctc caataaagcg
    21241 ttattgccgc tgttgtggga gatgttcccg gaccatccga atctgttgcc tgcgtatttc
    21301 gccgaagacg aacatccgcc aatggataaa tatgtcgtga aaccgatctt ctcccgcgaa
    21361 ggggcgaacg tatcgattat tgagaacggt aaaacgatcg aatccgtgga aggcccgtat
    21421 ggcgaagagg gtatgatcgt gcaacagttc tatccgctgc caaaattcgg cgacagttac
    21481 accctgattg gtagctggct gattaacgat caacccgccg gaattggtat ccgtgaagat
    21541 cgggcactga tcacccagga tctctcccgc ttctatccgc atatttttgt cgaaggatag
    21601 attttcctgt aagcccgatg cgcgtagcgc catcgggcaa tcattcagcg ccttatccgg
    21661 cctaccccac ctgcaccgac aacatactta tactgcccat ctcaataccg tcgaccggga
    21721 tggtgatagg ttccttgccg tcccaggcgc caagtacata cagcaaaggc aaaaagtgct
    21781 ccggcgtcgg gttcgataag gcgccccctt catgttgcag ataattcacc agcgggtgct
    21841 gttctaccgg cccctgccac gtcaggttag ctttcacaaa gtcattaaat gacgccgccc
    21901 agggatacgg tatattgtca ccgtgccaac gcacagtccg caggttatga accacattcc
    21961 cgctagccac cagcatcacg ccttcgtcac gcagcgtcgc cagtttacga cccatctcaa
    22021 aatgccatgc cgccggtttg gtactatcaa cactaagctg caccatcggg atatccgcat
    22081 tcgggtacat cttgatcaat acgccccagg agccgtgatc aaatccccac gcctctttat
    22141 cgagcgcgac gggaacggga gccaacagtt caaccagacg ctgcgccagc gcaggcgatc
    22201 caggggccgg ataatgcatg tcatacagcg cctgcggaaa accgccaaaa tcgtggagag
    22261 tttgcggcct ttccatcgct gtgacgcccg tcccacgggt ataccagtgc gccgacacca
    22321 ccactatcgc ctgtggtcgc ggtagggctt cccccaatcg ccgccaggcg cgggtataat
    22381 cattatcgtc cagcacgttc atcgggctgc catgccccaa aaacaatgct ggcatacacg
    22441 ttaaagacat gatgttatcc ttacaggaaa gacattttgt taacatcacc atacgctttc
    22501 ttcacagagg aagaactcag ataactatga tgaagatcat cagttatttt gaaggtcagg
    22561 ttcggacggc aaattgataa ggagtaatgg atgtcagtac cacttattct gaccttactg
    22621 gcgggcgctg ccacctttat tggcgcgttt cttggcgttc ttggccaaaa accgtctaac
    22681 cgcgtgctgg ctttttcgct gggcttcgcc gcagggatca tgctgctcat ctcgctgatg
    22741 gagatgctgc ccgccgcgtt agataccgag gggatgtcgc ctgtactggg ctacgggatg
    22801 tttattatcg gcctgttggg ctacttcggg ctggatcgtc tgcttcctca cgctcatccg
    22861 caggatctgg tgcaaaaaag gcagcagccg cttcccggct cgataaaacg cactgcgatt
    22921 ttattgacgc tcggcattag cctgcacaac tttccggaag gaatcgccac ctttgtcact
    22981 gccagcagca atcttgaact gggtttcggc atcgcactgg cggtggcgtt gcacaatatt
    23041 cctgaagggc tggcggttgc cggcccggtt tatgccgcga cgggctcaaa acgtaccgcg
    23101 attttttggg ccggtatctc cggcatggcg gaaattcttg gcggcgtgct ggcgtggctg
    23161 attttgggca gcctggtttc accgatcgtt atggcggcta tcatggcagc agtcgccggc
    23221 attatggtgg cgctctccgt cgatgaactg atgccgttgg caaaagagat cgatcctaac
    23281 aataacccca gctatggtgt gctttgcggt atgtccatca tggggctcag tctcgtcatt
    23341 ttgcagacga taggtatcgg ttaagagcaa cgtcgcgccg gatgcaggcc tttagccagg
    23401 caacatccgg ctgcccgtca aggatatgcg ctatttctgc tcattcatca cgctgtcgcc
    23461 ttcgctcgtc tggcgaaaac gtttcgttcg cgcttcaagt aatgcatctc tgtcttgccg
    23521 aaacgctctg caataacgct tcatatggca aatataccct actaccacca gaacgattaa
    23581 tattatccaa taccaggcaa taaacatcct ttttaccctt aaaatttaac atcactaaac
    23641 atttaacgtt aaaattttac
//
LOCUS       DAJVBX010000052        23557 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.052, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000052 DAJVBX010000000
VERSION     DAJVBX010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 23557)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23557)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23557
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.052"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            20..433
                     /locus_tag="OPV72_001784"
     CDS             20..433
                     /locus_tag="OPV72_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCR9914112.1"
                     /translation="MKKVAIVGALLVLAGCAEVENYNDVVKTPAPAGLEGYWQSKGPQ
                     RKLVSPEAIASLVVTKEGDTLDCRQWQRVIALPGKLTMLSDDLTNVTVKRELYEIERD
                     GNTLEYDGMTLQRVARPTPECAAALEKTPLPTPLP"
     gene            complement(473..1957)
                     /gene="amyA"
                     /locus_tag="OPV72_001785"
     CDS             complement(473..1957)
                     /gene="amyA"
                     /locus_tag="OPV72_001785"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HCR9914113.1"
                     /translation="MKNPTLLQYFHWYYPDGGKLWSELAERADGLNDIGINMVWLPPA
                     CKGASGGYSVGYDSYDLFDLGEFDQKGTIATKYGDKRQLLTAIDALKKNNIAVLLDVV
                     VNHKMGADEKERIRVQRVNQDDRTQIDDNIIECEGWTRYTFPARAGQYSNFIWDYHCF
                     SGIDHIENPDEDGIFKIVNDYTGDGWNDQVDDELGNFDYLMGENIDFRNHAVTEEIKY
                     WARWVMEQTHCDGFRLDAVKHIPAWFYKEWIEHVQAVAPKPLFIVAEYWSHEVDKLQT
                     YIDQADGKTMLFDAPLQMKFHEASRQGAEYDMRHIFTGTLVEADPFHAVTLVANHDTQ
                     LLQALEAPVEPWFKPLAYALILLRENGVPSVFYPDLYGASYEDNGENGETCRVDMPVI
                     NQLDRLILARQRFAHGIQTLFFDHPNCIAFSRSGTEENPGCVVVLSNGDDGEKTLLLG
                     DNYANKTWRDFLGNRSEHVVTNDQGEATFFCNAGSVSVWVIEDV"
     gene            complement(2029..2397)
                     /gene="fliT"
                     /locus_tag="OPV72_001786"
     CDS             complement(2029..2397)
                     /gene="fliT"
                     /locus_tag="OPV72_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis regulatory protein FliT"
                     /protein_id="HCR9914114.1"
                     /translation="MTSTVEFINRWQRIALLSQSLLELAQRGEWDLLLQQEVSYLQSI
                     ETVMEKQTPPGITRSIQDMVAGYIKQTLDNEQLLKGLLQQRLDELSSLIGQSTRQKSL
                     NNAYGRLSGMLLVPDAPGAS"
     gene            complement(2397..2804)
                     /gene="fliS"
                     /locus_tag="OPV72_001787"
     CDS             complement(2397..2804)
                     /gene="fliS"
                     /locus_tag="OPV72_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HCR9914115.1"
                     /translation="MYTASGIKAYAQVSVESAVMSASPHQLIEMLFDGANSALVRARL
                     FLEQGDVVAKGEALSKAINIIDNGLKAGLDQEKGGEIATNLSELYDYMIRRLLQANLR
                     NDAQAIEEVERLLSNIAEAWKQISPKASFQESR"
     gene            complement(2819..4222)
                     /gene="fliD"
                     /locus_tag="OPV72_001788"
     CDS             complement(2819..4222)
                     /gene="fliD"
                     /locus_tag="OPV72_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar filament capping protein FliD"
                     /protein_id="HCR9914116.1"
                     /translation="MASISSLGVGSNLPLDQLLTDLTKNEKGRLTPITKQQSANSAKL
                     TAYGTLKSALEKFQTANTALNKADLFKSTVASSTTEDLKVSTTAGAAAGTYKISVTQL
                     AAAQSLATKTTFATTKEQLGDTSVTSRTIKIEQPGRKEPLEIKLDKGDTSMEAIRDAI
                     NDADSGIAASIVKVKENEFQLVLTANSGTDNTMKITVEGDTKLNDLLAYDSTTNTGNM
                     QELVKAENAKLNVNGIDIERQSNTVTDAPQGITLTLTKKVTDATVTVTKDDTKAKEAI
                     KSWVDAYNSLVDTFSSLTKYTAVEPGEEASDKNGALLGDSVVRAIQTGIRAQFANSGS
                     NSAFKTMAEIGITQDGTSGKLKIDDDKLTKVLKDNTAAARELLVGDGKETGITTKIAT
                     EVKSYLADDGIIDNAQDNVNATLKSLTKQYLSVSNSIDETVARYKAQFTQLDTMMSKL
                     NNTSSYLTQQFTAMNKS"
     gene            4479..5999
                     /locus_tag="OPV72_001789"
     CDS             4479..5999
                     /locus_tag="OPV72_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliC/FljB family flagellin"
                     /protein_id="HCR9914117.1"
                     /translation="MAQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDD
                     AAGQAIANRFTANIKGLTQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANG
                     TNSQSDLDSIQAEITQRLNEIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDL
                     KEISSKTLGLDKLNVQDAYTPKETAVTVDKTTYKNGTDPITAQSNTDIQTAIGGGATG
                     VTGADIKFKDGQYYLDVKGGASAGVYKATYDETTKKVNIDTTDKTPLATAEATAIRGT
                     ATITHNQIAEVTKEGVDTTTVAAQLAAAGVTGADKDNTSLVKLSFEDKNGKVIDGGYA
                     VKMGDDFYAATYDEKTGAITAKTTTYTDGTGVAQTGAVKFGGANGKSEVVTATDGKTY
                     LASDLDKHNFRTGGELKEVNTDKTENPLQKIDAALAQVDTLRSDLGAVQNRFNSAITN
                     LGNTVNNLSSARSRIEDSDYATEVSNMSRAQILQQAGTSVLAQANQVPQNVLSLLR"
     gene            6078..7282
                     /gene="fliB"
                     /locus_tag="OPV72_001790"
                     /pseudo
     CDS             6078..7282
                     /gene="fliB"
                     /locus_tag="OPV72_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460911.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin lysine-N-methylase"
     gene            7479..8198
                     /locus_tag="OPV72_001791"
     CDS             7479..8198
                     /locus_tag="OPV72_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor FliA"
                     /protein_id="HCR9914118.1"
                     /translation="MNSLYTAEGVMDKHSLWQRYVPLVRHEALRLQVRLPASVELDDL
                     LQAGGIGLLNAVDRYDALQGTAFTTYAVQRIRGAMLDELRSRDWVPRSVRRNAREVAQ
                     AMGQLEQELGRNATETEVAERLGIPVAEYRQMLLDTNNSQLFSYDEWREEHGDSIELV
                     TEEHQQENPLHQLLEGDLRQRVMDAIESLPEREQLVLTLYYQEELNLKEIGAVLEVGE
                     SRVSQLHSQAIKRLRTKLGKL"
     gene            8257..8808
                     /gene="fliZ"
                     /locus_tag="OPV72_001792"
     CDS             8257..8808
                     /gene="fliZ"
                     /locus_tag="OPV72_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis regulatory protein FliZ"
                     /protein_id="HCR9914119.1"
                     /translation="MTVQQPKRRPLSRYLKDFKHSQTHCAHCHKLLDRITLVRRGKIV
                     NKIAISQLDMLLDDAAWQREQKEWVALCRFCGDLHCKKQSDFFDIIGFKQYLFEQTEM
                     SHGTVREYVVRLRRLGNYLSEQNISHDLLQDGFLDESLAPWLPETSTNNYRIALRKYQ
                     QYKAHQQIAPRQKSPFTASSDIY"
     gene            8955..9755
                     /gene="tcyJ"
                     /locus_tag="OPV72_001793"
     CDS             8955..9755
                     /gene="tcyJ"
                     /locus_tag="OPV72_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystine ABC transporter substrate-binding
                     protein"
                     /protein_id="HCR9914120.1"
                     /translation="MKLALLGRQALMGVMAVALVAGMSAKSFADEGLLNKVKERGTLL
                     VGLEGTYPPFSFQGDDGKLTGFEVDFAEALAKHLGVKASLKPTKWDGMLASLDSKRID
                     VVINQVTISDVRKKKYDFSTPYTVSGVQALVKKGNEGTIKTAADLQGKKVGVGLGTNY
                     EEWLRQHVQGVDIRTYDDDPTKYQDLRVGRIDAILVDRLAALDLVKKTKGTLAVTGDA
                     FSRQESGVALRKGNEDLLKAVDNAIAEMQKDGTLKALSEKWFGADVTQ"
     gene            9909..10895
                     /gene="dcyD"
                     /locus_tag="OPV72_001794"
     CDS             9909..10895
                     /gene="dcyD"
                     /locus_tag="OPV72_001794"
                     /EC_number="4.4.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-cysteine desulfhydrase"
                     /protein_id="HCR9914121.1"
                     /translation="MPLHHLTRFPRLELIGAPTPLEYLPRLSDYLGREIYIKRDDVTP
                     IAMGGNKLRKLEFLVADALREGADTLITAGAIQSNHVRQTAAVAAKLGLHCVALLENP
                     IGTTAENYLTNGNRLLLDLFNTQIEMCDALTDPDAQLQTLATRIEAQGFRPYVIPVGG
                     SSALGAMGYVESALEIVQQCEEVVGLSSVVVASGSAGTHAGLAVGLEHLMPDVELIGV
                     TVSRSVAEQKPKVIALQQAIAGQLALTATADIHLWDDYFAPGYGVPNDAGMEAVKLLA
                     NLEGVLLDPVYTGKAMAGLIDGISQKRFNDDGPILFIHTGGAPALFAYHPHV"
     gene            10916..11584
                     /gene="tcyL"
                     /locus_tag="OPV72_001795"
     CDS             10916..11584
                     /gene="tcyL"
                     /locus_tag="OPV72_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystine ABC transporter permease"
                     /protein_id="HCR9914122.1"
                     /translation="MQESIQLVIESLPYLLKGAVFTLQLSIGGMFFGLLLGFVLALMR
                     MSPLWPVRWLARFYISIFRGTPLIAQLFMIYYGLPQFGIELDPIPAAMIGLSLNTAAY
                     TSETLRAAISAIDKGQWEAAASIGMTPWQTLRRAILPQAARVALPPLSNSFISLVKDT
                     SLAATIQVPELFRQAQLITSRTLEVFTMYLAASLIYWVMATVLSALQNYFENQLNRQE
                     REPK"
     gene            11581..12333
                     /gene="yecC"
                     /locus_tag="OPV72_001796"
     CDS             11581..12333
                     /gene="yecC"
                     /locus_tag="OPV72_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine ABC transporter ATP-binding protein
                     YecC"
                     /protein_id="HCR9914123.1"
                     /translation="MSAIEVTNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTT
                     LLRCINLLEQPEAGTIKVGDIIIDTARPFSQQKGLIRQLRQHVGFVFQSFNLFPHRTV
                     LENIIEGPVIVKGEPKAEATALARELLAKVGLAGKETRYPRRLSGGQQQRVAIARALA
                     MRPEVILFDEPTSALDPELVGEVLNTIRQLAQEKRTMVIVTHEMGFARDVADRAIFMD
                     QGQIVEQGPAKTLFADPQHPRTRQFLEKFLVK"
     gene            12566..13288
                     /gene="sdiA"
                     /locus_tag="OPV72_001797"
     CDS             12566..13288
                     /gene="sdiA"
                     /locus_tag="OPV72_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SdiA"
                     /protein_id="HCR9914124.1"
                     /translation="MQENDFFTWRRAMLLRFQEMAAAEDVYTELQYQTQRLEFDYYAL
                     CVRHPVPFTRPKISLRTTYPQAWVTHYQSENYFAIDPVLKPENFRQGHLHWDDVLFHE
                     AQAMWDAAQRFGLRRGVTQCVMLPNRALGFLSFSRSSLRCSSFTYDEVELRLQLLARE
                     SLSALTRLEDDMVMAPEMRFSKREKEILKWTAEGKTSSEIAIILSISENTVNFHQKNM
                     QKKFNAPNKTQIACYAAATGLI"
     gene            complement(13355..13579)
                     /locus_tag="OPV72_001798"
     CDS             complement(13355..13579)
                     /locus_tag="OPV72_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2594 family protein"
                     /protein_id="HCR9914125.1"
                     /translation="MSTPDFSTAENNQELATEVNCLKAMLTLMLQAMGQADAGRVILK
                     MEKQIAQMDDEAQAAVFSSTVKQIKQAYRQ"
     gene            complement(13576..13731)
                     /locus_tag="OPV72_001799"
     CDS             complement(13576..13731)
                     /locus_tag="OPV72_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_448360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914126.1"
                     /translation="MHHAATFILWVTPLLFDQKTTTAIFSVAYGILRRLNICYRTFSL
                     KHNEENK"
     gene            14043..14699
                     /gene="uvrY"
                     /locus_tag="OPV72_001800"
     CDS             14043..14699
                     /gene="uvrY"
                     /locus_tag="OPV72_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrY/SirA/GacA family response regulator
                     transcription factor"
                     /protein_id="HCR9914127.1"
                     /translation="MINVLLVDDHELVRAGIRRILEDIKGIKVVGEACCGEDAVKWCR
                     TNAVDVVLMDMNMPGIGGLEATRKIARSTADIKVIMLTVHTENPLPAKVMQAGAAGYL
                     SKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPAKTETPFASLSERELQIMLM
                     ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLTSQ
                     "
     gene            14696..16528
                     /gene="uvrC"
                     /locus_tag="OPV72_001801"
     CDS             14696..16528
                     /gene="uvrC"
                     /locus_tag="OPV72_001801"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HCR9914128.1"
                     /translation="MSEIFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLS
                     SYFRSNLASRKTEALVAQIQHIDVTVTHTETEALLLEHNYIKLYQPRYNVLLRDDKSY
                     PFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
                     NRSRPCLQYQIGRCLGPCVAGLVSEEEYTQQVEYVRLFLSGKDDQVLTQLIARMEKAS
                     QDLAFEEAARIRDQIQAVRRVTEKQFVSNAGDDLDVIGVAFDAGMACVHVLFIRQGKV
                     LGSRSYFPKVPGGTELGEVVETFVGQFYLQGSQMRTLPGEILLDFNLSDKTLLADSLS
                     ELAGRRIHVQTKPRGDRARYLKLARTNAATALVTKLSQQSTITQRLTALATVLKLPAI
                     KRMECFDISHTMGEQTVASCVVFDANGPLRAEYRRYNIAGITPGDDYAAMNQVLRRRY
                     GKAIEESKIPDVILIDGGKGQLAQAKAVFAELDVPWDKHRPLLLGVAKGADRKAGLET
                     LFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSTLETIEGVGP
                     KRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH"
     gene            16585..17133
                     /gene="pgsA"
                     /locus_tag="OPV72_001802"
     CDS             16585..17133
                     /gene="pgsA"
                     /locus_tag="OPV72_001802"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HCR9914129.1"
                     /translation="MQFNIPTLLTLFRVILIPFFVVVFYLPFAWAPMVSALIFCIAAI
                     TDWFDGFLARRWNQSTRFGAFLDPVADKVLVAIAMVLVTEHYHSWWVTLPAATMIARE
                     IIISALREWMAELGKRSSVAVSWIGKVKTTAQMVALAWLLWRPNIWVEYAGIALFFVA
                     AVLTLWSMLQYLSAARGDLLDQ"
     gene            17285..17360
                     /locus_tag="OPV72_001803"
     tRNA            17285..17360
                     /locus_tag="OPV72_001803"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17318..17320,aa:Gly,seq:gcc)
     gene            17413..17486
                     /locus_tag="OPV72_001804"
     tRNA            17413..17486
                     /locus_tag="OPV72_001804"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17445..17447,aa:Cys,seq:gca)
     gene            17498..17584
                     /locus_tag="OPV72_001805"
     tRNA            17498..17584
                     /locus_tag="OPV72_001805"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17532..17534,aa:Leu,seq:taa)
     gene            17834..18164
                     /locus_tag="OPV72_001806"
                     /pseudo
     CDS             17834..18164
                     /locus_tag="OPV72_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460897.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            18378..19817
                     /locus_tag="OPV72_001807"
     CDS             18378..19817
                     /locus_tag="OPV72_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HCR9914130.1"
                     /translation="MMMQKKTWAVLLIPLCLTACHQTTNRSTAKDEILTGSYIDPTKT
                     RFPLADYSQSVDKWIPPDSADYTIPVIDSATQQRYFSALKSHYFGMDSEAHSPWNDFY
                     ITALLKKNAAQARDASIKQFLSDGSAYWGENFRLYTSRWKEEVRGNTDTQIDNIYHAS
                     RRGIMVRESLVRALPTDDPLFNDPRQAGEGYPFDNLQMSSLRPGTPVYTLTKSKDQRW
                     QYVVSPAVTGWVHSEDIASTDQKFITQWVLLAHKQLGAFINAPVSVHAAGVYYFTGRP
                     GTILPFRHQRAGQFLIAAPVRGSNGRAFIHWVWLSGNEFTAMPWKMTPENIAVLMKAM
                     HGAPYGWGNFNFYNDCSAEVRSLLMPFGIFLPRHSSAQVESAGRVVDLSHKNPQMRID
                     YLTRYGKAFTTLVYIPGHIMLYIGNTTMNGQVVPMTYQNIWGLRPNHANSRSIIGEAV
                     FLPLLRFYPENPELISLAGKVLFKLGYIE"
     gene            20030..20355
                     /locus_tag="OPV72_001808"
                     /pseudo
     CDS             20030..20355
                     /locus_tag="OPV72_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460895.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
     gene            20594..21259
                     /locus_tag="OPV72_001809"
     CDS             20594..21259
                     /locus_tag="OPV72_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YecA family protein"
                     /protein_id="HCR9914131.1"
                     /translation="MKMEPLNENELEWLDDVLTKYNTDQVILDVAELDGLITAVLSSP
                     RPIEPEQWLVAIWGGPAYVPRWTSEKEMTRFMDLVFQHMADTAARLEDYPEQFEPLFG
                     LREVDGHELTIVEEWCFGYMRGVSLSDWSDLPDTLKPALEAIALHGTEENFALLDKMS
                     PEAFDKSVDAIRIAALELHAWWMAHPHTTPLQMPIKAEVKVGRNDPCPCGSGKKFKQC
                     CLH"
     gene            complement(21334..22545)
                     /gene="tyrP"
                     /locus_tag="OPV72_001810"
     CDS             complement(21334..22545)
                     /gene="tyrP"
                     /locus_tag="OPV72_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine transporter TyrP"
                     /protein_id="HCR9914132.1"
                     /translation="MKNRTLGSIFIVAGTTIGAGMLAMPLAAAGVGFSVTLGLLIGLW
                     ALMCYTALLLLEVYQHVPADTGLGSLAKRYLGRYGQWLTGFSMMFLMYALTAAYISGA
                     GELLASSINNWLGATLSPAAGVLLFTFVAGGVVCVGTSLVDLFNRFLFSAKIIFLVIM
                     LALLTPHIHKVNLLTLPLQQGLALSAIPVIFTSFGFHGSVPSIVSYMNGNIRRLRWVF
                     MTGSAIPLVAYIFWQLATLGSIDSPTFRGLLASHAGLNGLLQALREVVASPHVELAVH
                     LFADLALATSFLGVALGLFDYLADLFQRRSTVSGRLQTGLITFLPPLAFALFYPRGFV
                     MALGYAGVALAVLALLIPAMLVWQCRKQSPQAGYRVAGGTPALALVFICGIVVIGVQF
                     SIALGFLPDPG"
     gene            22772..23011
                     /locus_tag="OPV72_001811"
     CDS             22772..23011
                     /locus_tag="OPV72_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YecH family protein"
                     /protein_id="HCR9914133.1"
                     /translation="MDSIHGHEVLNMMIESGEQYTHTSLEAAIKARFGERARFHTCSA
                     SDMTAAELVAFLAAKGKFIAVEDGFSTHESKICRH"
     gene            complement(23057..23554)
                     /gene="ftnA"
                     /locus_tag="OPV72_001812"
     CDS             complement(23057..23554)
                     /gene="ftnA"
                     /locus_tag="OPV72_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="non-heme ferritin"
                     /protein_id="HCR9914134.1"
                     /translation="MLKTEMIDKLNEQMNLELYSSLLYQQMSAWCSYHSFEGAAAFLR
                     RHAQEEMTHMQRLFDYLTDTGSLPRINSVSSPFAEYTSLDELFRATYEHEQLITQKIN
                     ELAHAAMTSQDYPTFNFLQWYVAEQHEEEKLFKSIIDKLTLAGKSGEGLYFIDKELST
                     LDTQN"
BASE COUNT         5844 a         5669 c         6203 g         5841 t
ORIGIN      
        1 ttctgatgca ggatgaatga tgaaaaaagt agcgatcgtt ggcgcattgc tggttctggc
       61 cggatgcgcc gaggtggaaa actataatga tgtggtgaaa acgcccgcgc cggccggtct
      121 ggaagggtac tggcagtcaa aaggcccgca acgtaagctg gtgagccctg aagctatcgc
      181 cagcctggtg gtgactaaag aaggcgatac gctggactgc cgccagtggc agcgcgttat
      241 tgctctgccg ggcaagctga ccatgctctc cgatgactta accaatgtta cggttaagcg
      301 tgagctctat gagattgagc gcgacgggaa taccctggaa tatgatggca tgacgctgca
      361 acgggtcgct cgtccgacgc cggagtgcgc cgccgcgtta gaaaaaacgc cgctgccgac
      421 gccgctgccg taatttcgct tcccggcagc gctctgccgc cgggaacgct catcacacgt
      481 cctcaatgac ccacacgctg acgctgcctg cgttgcagaa gaacgtcgct tcgccttgat
      541 cattagttac aacatgctca ctgcggtttc ccagaaaatc acgccaggtc ttgttagcgt
      601 aattgtcgcc gagcaggagg gttttttcac cgtcgtcgcc attggaaagt acgaccacac
      661 agcctggatt ctcttcagta ccgctgcgac taaaggcgat acagttggga tgatcgaaaa
      721 agagtgtttg tataccgtgc gcaaaacgct gacgagcgag gatcagccga tccagttggt
      781 taatcaccgg catgtcgacc cgacaggtct cgccattttc gccgttatcc tcatagctgg
      841 cgccgtataa atcgggataa aacaccgacg gtacgccgtt ttcacgaagc aggatcagcg
      901 cataggccaa tggtttgaac cagggttcta ccggcgcttc cagcgcctgt aacagttgtg
      961 tatcgtggtt agcgaccagc gtcaccgcat gaaaagggtc ggcttctacc agcgtgccgg
     1021 tgaaaatgtg gcgcatgtca tactccgcgc cctggcgcga ggcttcatga aatttcatct
     1081 gcaacggcgc gtcgaacagc atggttttcc cgtcggcctg atcgatgtac gtttgcagtt
     1141 tatccacttc atgcgaccag tattctgcga caataaacag cggttttggc gcaaccgcct
     1201 gtacatgctc aatccattct ttataaaacc aggcgggtat atgttttacc gcgtccaggc
     1261 gaaagccgtc acaatgggtt tgttccatga cccaacgagc ccaatattta atctcttccg
     1321 taaccgcgtg attgcgaaaa tcgatatttt cccccatcag atagtcgaaa ttacccagct
     1381 catcatcaac ctgatcgttc cagccatcgc cggtatagtc attgacgatc ttaaaaatgc
     1441 cgtcttcgtc gggattctcg atgtgatcaa tgccgctgaa acagtgatag tcccaaataa
     1501 agttggaata ctggcccgcg cgggcaggga aggtgtagcg cgtccagcct tcgcattcaa
     1561 tgatgttgtc atcaatttgc gtgcggtcat cctgattcac gcgctgaacg cgaatacgtt
     1621 ctttttcgtc tgcgcccatt ttgtggttca cgacgacgtc gagcagcacc gcaatattat
     1681 tttttttgag cgcgtctatc gccgtcagta actggcgttt atcgccgtac tttgtcgcga
     1741 tagttccttt ttggtcaaat tcgccgaggt caaacaggtc gtagctatca tagcctacgg
     1801 aatagccgcc ggaggcgcct ttacaggcgg gcggtagcca gaccatattg ataccgatat
     1861 cattcagccc atcagcacgt tccgccagct cagaccagag ttttcctccg tcgggataat
     1921 accagtggaa gtactgcaat aacgtggggt ttttcatctt ccgtgctcca gaagtcgttt
     1981 agccgacctc tggagtatgg aagaattttc atacgagacg ggaaaatatt atgaggcgcc
     2041 aggtgcgtct ggcacgagta acataccgga aagacggcca taagcgttgt tgagtgattt
     2101 ttggcgggtg gattgtccga tcaaactact cagttcatcc agtcgctgtt gcagcagccc
     2161 tttcaggagc tgctcattat ccagcgtttg tttgatgtat ccggcgacca tatcctgaat
     2221 acttcgcgta atgcccggtg gagtttgctt ttccatcacc gtttcaatac tttgcagata
     2281 ggagacctct tgttgcagta agagatccca ttcacctcgc tgcgcaagtt caagcagcga
     2341 ttgactgagc agcgcaatac gctgccaacg gttgataaac tccacggttg aggtcattaa
     2401 cgagactcct ggaaagatgc tttcggtgaa atctgcttcc aggcttctgc aatattgctg
     2461 agtaaccttt ccacttcttc gatggcctga gcgtcgttac gcaaattagc ctgcagtaaa
     2521 cggcgaatca tatagtcgta tagctcggaa agattcgtcg caatctcacc gcctttttcc
     2581 tgatcgaggc cggctttcag cccgttatcg ataatattga tggctttgct taacgcttca
     2641 cctttcgcga caacatcgcc ttgttctaaa aacaggcgag cgcgcaccag agcgctattc
     2701 gcgccatcaa acaacatttc aatcaactga tgcgggctgg cgctcatcac ggcgctttcc
     2761 acgctgactt gcgcataagc tttgataccg ctcgcggtgt acatggtgac ctctgttatc
     2821 aggacttgtt catagctgta aattgctggg tcaaataact actggtgtta ttcagcttac
     2881 tcatcatggt atccagttgg gtaaactggg ccttgtaacg ggcaacggtt tcatcgatgc
     2941 tgttgctaac ggacaggtac tgttttgtca ggcttttcag cgtggcgtta acgttgtcct
     3001 gcgcattatc aataatgccg tcatccgcca gataactttt cacttcggtg gcaattttgg
     3061 tggtgatacc cgtttcttta ccatcgccta ccagcagctc acgcgctgcg gccgtgttat
     3121 ctttcagtac cttggtcagc ttatcatcgt caatcttcag tttgccggaa gtcccatcct
     3181 gggtgatgcc aatttccgcc attgttttga acgcagaatt actgccgcta ttggcaaatt
     3241 gtgcccgaat cccggtctgg atagcacgaa ccacactatc gcctaacagc gcgccgtttt
     3301 tatcgctggc ttcttcgccc ggctcaacgg cggtatattt agttaatgag ctaaaagtat
     3361 ccaccagcga gttataggca tccacccagg atttaatcgc ctctttcgcc ttggtatcat
     3421 ctttcgtcac cgtcacggtc gcgtcggtca ctttcttggt cagggtgagt gtaattccct
     3481 gaggggcgtc ggttacggta ttgctctgac gctcaatgtc gatgccgttt acgttcagct
     3541 tcgcgttttc tgctttcacc agctcttgca tattgccggt attggtggtg ctgtcataag
     3601 cgagtagatc gttaagtttt gtatcgcctt ccaccgtgat cttcatcgta ttgtcggtac
     3661 cgctattggc ggtaagcacc aactggaatt cgttctcttt gaccttaacg atactggcgg
     3721 cgataccgct gtcggcgtca ttaatggcgt cacggatcgc ctccatggag gtgtcgcctt
     3781 tatccagctt aatttccagc ggctctttac gtcccggctg ttcaatttta attgtccggg
     3841 atgtgaccga cgtatcgccc aactgctctt tggtggttgc gaaggtggtt tttgtcgcca
     3901 gcgactgcgc ggcggcaagc tgggttacgc taatcttata agtccctgcg gcagcgcctg
     3961 cggtagtact gactttgagg tcctctgtcg tgctggacgc cacggtagac ttaaataaat
     4021 ccgctttatt taacgcggta tttgccgtct ggaatttttc taatgcgctt ttcaatgtgc
     4081 cataggcggt tagctttgcc gaattcgcgc tctgctgttt ggtaattggc gttaagcgtc
     4141 ctttttcgtt ctttgtcagg tctgtcaaca actggtctaa cggtaagttt gatcccacac
     4201 ctaatgatga aattgaagcc atgccttctt cctttttgat tgcaaacagt agttaagcgc
     4261 gttatcggca atctggaggc aaagtttaat gataattttg caaaaataat gcgcggaata
     4321 atgatgcata aagcggctat ttcgccgcct aagaaaaaga tcgggggaag tgaaaaattt
     4381 tctaaagttc gaaattcagg tgccgataca agggttacgg tgagaaaccg tgggcaacag
     4441 cccaataaca tcaaattgta attgataagg aaaagatcat ggcacaagtc attaatacaa
     4501 acagcctgtc gctgttgacc cagaataacc tgaacaaatc ccagtccgca ctgggcactg
     4561 ctatcgagcg tttgtcttcc ggtctgcgta tcaacagcgc gaaagacgat gcggcaggac
     4621 aggcgattgc taaccgtttt accgcgaaca tcaaaggtct gactcaggct tcccgtaacg
     4681 ctaacgacgg tatctccatt gcgcagacca ctgaaggcgc gctgaacgaa atcaacaaca
     4741 acctgcagcg tgtgcgtgaa ctggcggttc agtctgcgaa tggtactaac tcccagtctg
     4801 acctcgactc catccaggct gaaatcaccc agcgcctgaa cgaaatcgac cgtgtatccg
     4861 gccagactca gttcaacggc gtgaaagtcc tggcgcagga caacaccctg accatccagg
     4921 ttggtgccaa cgacggtgaa actatcgata ttgatttaaa agaaatcagc tctaaaacac
     4981 tgggacttga taagcttaat gtccaagatg cctacacccc gaaagaaact gctgtaaccg
     5041 ttgataaaac tacctataaa aatggtacag atcctattac agcccagagc aatactgata
     5101 tccaaactgc aattggcggt ggtgcaacgg gggttactgg ggctgatatc aaatttaaag
     5161 atggtcaata ctatttagat gttaaaggcg gtgcttctgc tggtgtttat aaagccactt
     5221 atgatgaaac tacaaagaaa gttaatattg atacgactga taaaactccg ttggcaactg
     5281 cggaagctac agctattcgg ggaacggcca ctataaccca caaccaaatt gctgaagtaa
     5341 caaaagaggg tgttgatacg accacagttg cggctcaact tgctgcagca ggggttactg
     5401 gcgccgataa ggacaatact agccttgtaa aactatcgtt tgaggataaa aacggtaagg
     5461 ttattgatgg tggctatgca gtgaaaatgg gcgacgattt ctatgccgct acatatgatg
     5521 agaaaacagg tgcaattact gctaaaacca ctacttatac agatggtact ggcgttgctc
     5581 aaactggagc tgtgaaattt ggtggcgcaa atggtaaatc tgaagttgtt actgctaccg
     5641 atggtaagac ttacttagca agcgaccttg acaaacataa cttcagaaca ggcggtgagc
     5701 ttaaagaggt taatacagat aagactgaaa acccactgca gaaaattgat gctgccttgg
     5761 cacaggttga tacacttcgt tctgacctgg gtgcggttca gaaccgtttc aactccgcta
     5821 tcaccaacct gggcaatacc gtaaataacc tgtcttctgc ccgtagccgt atcgaagatt
     5881 ccgactacgc aaccgaagtc tccaacatgt ctcgcgcgca gattctgcag caggccggta
     5941 cctccgttct ggcgcaggcg aaccaggttc cgcaaaacgt cctctcttta ctgcgttaat
     6001 ccggcgattg attcaccgac acgtggtaca caatcaaggc agcgaaagct gcctttttta
     6061 attccggagc ctgtgtaatg aaagaaatca ccgtcactga acctgccttt gtcacccgct
     6121 tttcctgttc tggctcggcc tgtcgcgacc attgttgtaa gggctggaaa atcacgctgg
     6181 ataagacgac ggttaaaaag tatctcgcca gtaaagacac gacgattcgt accatcgcgc
     6241 aagaccatat tattctgctg aaaaagaaca ataatcattg gggggaaatt aaactgcctt
     6301 cggcgctggg aagttgccct tatctggatg aggaccgttt gtgccgggta caaaaacgtt
     6361 aggcgcaaag gcattaagtc atacctgttc ctctttccca cgggcgcacc atacctataa
     6421 aaatgaggta cgtaactccc tgagtcttgc ctgtccggag gtaacgtccc gcattttaaa
     6481 cgatcctgac gcaatggcgc tcggcgaaaa aacaatcatt cagcagacat tcaatactgc
     6541 gccgttattc tcaccgcagc aaaagttact caatctgttt tgcctgagtc tgatcaacca
     6601 tgccaacagc agtacggaaa cggcgctcta tgggttgatt aaattcgtca tgtatgcaca
     6661 taaatttgcc aaaattgatg atgccgcgct gggtgaactg gaacaggtgt atgccgcgtt
     6721 acttgagcag ttgcagaccg gcgtgctggc gcaggaattg atgaatatcg cgccggacag
     6781 caaggtaaaa acctcgctgg tattgcagat gcagaactat ttccgctcgc tcccgcttag
     6841 tcgtggcagt gttatcctcg atcactatat ccagtgtctt ctgcgggtgc tgacggcgga
     6901 agagggcgtt tcaatggagc agaaggttag cgatattgag tcctcattag cgcgctgttt
     6961 acaggcggat gagcagcaga agaactgggc tttcagaaat ttaattctct ataaaatttg
     7021 ggaaaataat ttccccaacc agccgaatgt cgacccgtta cgcgcgctgt atattatcgt
     7081 ggcggaatat gcctttatta agctattaac ggcagccagc gtgcatgagc gcgggcggct
     7141 tgagtgggat gacgttacca atattgtgta tagctttcac tcccgcagcc agcataacag
     7201 cgaggtggcg gcgaattttc atcgccatat agaaacggtg cgtactggcg acgatctgtc
     7261 gatgattcat cttctgacat agttttgttc ggggtgggct tttgcgcatc ccgtttatcc
     7321 tatctggctg attttattct gctctttgaa ccgctaaaaa ggcgctacag gttacataag
     7381 tgaaataacc cttcttttat agccttattc cttcgataga accctctgta gaaacggata
     7441 atcatgccga taactcattt aacgcagggc tgtttatcgt gaattcactg tataccgctg
     7501 aaggtgtaat ggataaacac tcgctgtggc agcgttatgt accgctggtg cgtcacgaag
     7561 cattgcgcct gcaggtgcga ttgccggcga gcgtggaact ggacgatctg ctacaagcgg
     7621 gcggcatcgg gttattaaat gcggtcgacc gatatgacgc tttgcaagga acggcattta
     7681 ccacttacgc agtgcagcgt attcgtgggg cgatgctgga tgaattacgc agccgcgatt
     7741 gggtgccgcg tagcgtccgg cgtaatgccc gcgaagtggc gcaggcgatg ggacaactgg
     7801 agcaggaact ggggcgtaat gcgacggaaa ccgaagtggc ggaacgtctt ggcatccctg
     7861 ttgcggagta tcgtcagatg ttgctcgata ccaacaacag ccaacttttc tcttacgatg
     7921 agtggcggga agagcatggc gatagcatcg aactggtgac tgaagaacat caacaggaaa
     7981 acccgttaca tcaactgctg gagggcgacc tgcgacagcg ggtaatggat gcgattgaat
     8041 cgctgccgga acgcgagcaa ctggtgttaa cgctgtatta ccaggaagag ctcaatctca
     8101 aagagattgg cgcggtactg gaagtcggcg aatcgcgggt cagccagttg catagtcagg
     8161 ccatcaaacg attacgcacc aaactgggta agttataggt agcgcatgat cgcacccgaa
     8221 aagtgccgca caacatatag actaccagga gttctcatga cggtgcagca acctaaaagg
     8281 cggcccttga gccgctatct taaagacttt aaacacagcc agacgcattg cgcgcattgt
     8341 cacaaattgc tcgaccgcat tacgctggtt cgccgtggca agatcgttaa taaaatcgct
     8401 atttcacagc tggatatgct acttgacgac gctgcctggc agcgggagca gaaggagtgg
     8461 gtggcgttgt gtcgcttttg cggcgatttg cactgcaaaa agcagagtga ttttttcgat
     8521 attatcggtt tcaagcagta tttgtttgaa caaaccgaga tgagccatgg cacggtgcgg
     8581 gaatatgtcg tgcgtttacg acgtcttggc aattacctca gcgagcaaaa catttcccac
     8641 gatctgctgc aggacggttt tctcgatgaa agcctggcgc catggttgcc ggaaaccagc
     8701 accaataatt accgtatcgc actgcgtaaa taccagcaat ataaagcgca tcagcagatt
     8761 gcgcccagac agaaatcccc ctttaccgcc agttctgata tatattaaaa aagcataaga
     8821 tgtagcagag tcgtgttggt gaaacgtggc aaaccttcta cattaggctg agtcccccaa
     8881 aggttcgcga gacgtgacga tgcgccatgg cgggacacag tctatggtca ttaacggcaa
     8941 tattcggggt tactatgaaa ttagcactgc tgggacgtca ggcactgatg ggagtaatgg
     9001 ctgtagcgct ggtggcggga atgagcgcga agagctttgc cgatgagggt ttgctgaaca
     9061 aagttaaaga acgcggcacg ctgctggtag ggctggaagg tacctatccg ccgtttagct
     9121 ttcagggcga cgacggcaaa ttaaccggtt ttgaagtcga tttcgccgag gcgttggcaa
     9181 aacatctggg cgttaaagcg tcgttgaagc cgaccaaatg ggacggaatg ctggcgtcgc
     9241 tggactctaa acgcattgat gtagtgataa accaggtcac gatttcagac gtccgcaaga
     9301 aaaaatatga tttctctacg ccttatactg tctccggcgt tcaggcgctg gtgaaaaaag
     9361 gcaatgaagg cacgatcaaa acggcggccg atctgcaggg caaaaaagtc ggcgttgggc
     9421 tggggactaa ctatgaagag tggctacgtc aacatgttca gggcgtggat atccgcacct
     9481 atgacgatga tcctacaaaa tatcaggatc tgcgcgtagg ccgtattgac gcgattttag
     9541 tcgatcgtct ggcggcgttg gatctggtga aaaaaaccaa aggtacgctg gccgtcaccg
     9601 gtgatgcgtt ttcgcgtcag gagtccggcg ttgcgttacg taaaggcaac gaagatttgc
     9661 tgaaggcggt agataatgcc attgcggaaa tgcaaaaaga tggcacctta aaagcgctct
     9721 ccgaaaaatg gtttggcgct gacgtgaccc aataatgctc tacgttgccc ggcaggtagt
     9781 gcgccgccgg gcaatatcaa cctcatacta tgtcagcaaa cggaggcgcg tgaatcggcg
     9841 ccttttttat ttccattaga tcaacgtgca taataaaaag aacacaccac aacgttaccg
     9901 gaggctcaat gccactacat cacttaacgc gctttcctcg cctggagctt attggcgcgc
     9961 cgaccccgct cgaatacctg ccgcgattgt ctgattatct tggccgtgag atttacatta
    10021 agcgcgatga cgttacgccc attgcaatgg gcggcaataa actgcgtaag ctggagtttc
    10081 tagtggccga cgcgctgcga gaaggggcgg atacgctgat aaccgcaggg gcgattcagt
    10141 caaaccatgt ccgtcagacg gcggcggttg cggccaaatt ggggctgcat tgcgtcgcct
    10201 tgctggaaaa tccaatcggt accaccgcgg aaaattacct gacgaatggt aatcgcctgt
    10261 tactggattt atttaataca caaattgaga tgtgcgatgc gctaaccgat ccggatgcgc
    10321 agctgcaaac gctggcgacg cgcattgaag cgcaagggtt caggccctat gtgattccgg
    10381 tcggcggctc cagcgcgttg ggcgcaatgg gatacgtaga gagcgccctg gagatcgtcc
    10441 agcagtgtga agaggtcgtc gggctctctt cggtggtggt ggcctccggc agcgccggaa
    10501 cgcacgccgg gttagctgtc gggctggaac atctgatgcc ggatgtcgaa ctgattggcg
    10561 tgaccgtttc acgttctgtc gccgagcaga aacccaaagt gattgccttg cagcaggcta
    10621 ttgccggcca gctggcgctg acggcgacgg cggatattca tttatgggat gactattttg
    10681 ccccgggtta cggcgtgcca aatgacgcgg ggatggaggc ggtgaaactg ctggcgaacc
    10741 tggagggggt gctgctggat ccggtatata ccggtaaagc gatggcgggt ctgatagatg
    10801 gcatcagcca gaaacgcttt aacgatgacg ggccgattct ctttattcat accggtgggg
    10861 cgcctgcgct gtttgcctac catcctcatg tataacctcc aggtaatcaa cgcgaatgca
    10921 agaaagtatc caactggtta ttgaatcgct gccgtatttg cttaaaggcg ccgtctttac
    10981 cctgcaactg agtattggcg gtatgttttt tggtctgctg ctgggatttg tgctggcgct
    11041 gatgcggatg tctccgctat ggccggttcg ctggctggcg cgcttttata tctcgatttt
    11101 tcgcggtacg ccgcttatcg cccagttatt tatgatctat tacggcctgc cgcaatttgg
    11161 tattgagctg gaccctatcc cggcggcgat gattggttta tcgctcaata ccgcggctta
    11221 cacgtccgag acgctgcgcg cggcgatctc ggctatcgac aagggacaat gggaagcggc
    11281 ggcgagcatt ggcatgacgc cgtggcaaac gctacgccgc gctattttgc cgcaggcggc
    11341 ccgcgtcgcg cttccgccgt tgagcaacag ctttatcagc ctggtgaaag atacatcgct
    11401 cgccgcgacg attcaggtgc cggagttgtt ccgccaggcg cagttaatta cctcgcgaac
    11461 gctggaggtg tttaccatgt atctggccgc gtcgttaatc tactgggtaa tggcgaccgt
    11521 cttatcggca ctgcaaaact atttcgaaaa ccagcttaac cgccaggaga gagagccaaa
    11581 atgagtgcta tcgaagtcac caacctggtc aaaaaatttc atggtcaaac ggtgctgcac
    11641 ggtatcgacc ttgaggtgaa gcccggagaa gtcgtcgcca ttatcggccc gagcggctca
    11701 gggaagacaa cgttattacg ctgtattaac ctgctggaac aaccggaagc gggcaccatt
    11761 aaagtaggcg atattatcat cgataccgcc cgcccattca gccagcaaaa agggttgatt
    11821 cgccagctac gtcagcatgt cggctttgtc tttcagagtt ttaacctgtt cccgcatcgt
    11881 accgtgctgg aaaatatcat tgaaggtccg gtgattgtaa agggagagcc gaaagctgag
    11941 gcgacggcgc tggcgcggga actgttagcc aaagtcgggt tggccggtaa agagacccgt
    12001 tatccgcgcc gcctgtcggg cgggcaacag cagcgcgtgg cgattgcgcg cgcgctggcg
    12061 atgcgcccgg aagtgattct gtttgatgag ccgacgtcgg cgcttgatcc tgaattagtc
    12121 ggcgaggtgc ttaatacgat tcgccagctg gcgcaggaaa agcgcacgat ggtgatcgtc
    12181 actcacgaaa tgggctttgc gcgtgacgtg gctgaccggg caatatttat ggatcagggg
    12241 caaatcgtcg aacaggggcc ggcgaaaacc ttgttcgccg atcctcagca tccgcgtact
    12301 cgccagttcc ttgagaaatt tttagtgaaa taataccttt tcaacgctcg cccgaattag
    12361 ccgtgcctcg ggcgagcgca atgaataatt atgaagtcat tctgccagat tattaacctc
    12421 gctctttggc ggaagtcgaa aaactgtaat gccgctcaag tattctatga ttcgtccgat
    12481 attccttata tataaacacc atttatgtgt taatttaagt cattcataat aatgattatc
    12541 aatatcaaag gcgtgaccat aaaatatgca ggaaaatgat ttcttcacct ggcgacgcgc
    12601 aatgttgtta cgctttcagg agatggcggc agcagaggat gtttatactg aattgcaata
    12661 tcagacacag cggctggaat ttgattatta tgccctgtgt gttcgtcatc ccgttccctt
    12721 tacccggcct aaaatatcgc ttcgtaccac ttatcctcag gcgtgggtaa cgcattatca
    12781 gtccgaaaac tatttcgcga ttgatccggt attaaagccg gaaaatttca ggcagggtca
    12841 tttacattgg gatgacgtgc tatttcatga agcgcaggcg atgtgggatg ccgcccagcg
    12901 tttcggatta cgcagaggcg taacccagtg tgtgatgttg ccgaaccggg cgctgggctt
    12961 tttatctttc tcccgtagca gtttacgctg ctcctcgttt acctacgatg aagtggagct
    13021 gaggttgcaa ctgctggcgc gggagagtct ttcggcgctg acaagacttg aagacgacat
    13081 ggtgatggcg cctgagatgc gtttcagtaa acgtgagaaa gagattctga agtggacggc
    13141 ggaagggaag acctcatcgg agatcgccat tattctgtcg atttctgaaa ataccgttaa
    13201 cttccatcag aaaaacatgc agaagaaatt caatgcgcca aataaaacac agattgcctg
    13261 ctacgctgcg gcgacaggtc tgatatgacg tgctgacgat gcttcgcgcc agacgcgaaa
    13321 ccggctgaaa gcgatgctaa cagccggttt tttactactg gcggtaagcc tgtttaattt
    13381 gcttaaccgt actggaaaat accgccgctt gtgcttcatc atccatctgc gcgatctgtt
    13441 tttccatttt aagaatcacg cgccctgcat cggcctggcc catcgcctgc agcatcagcg
    13501 ttaacatggc tttcaggcag ttgacttcag tagccagttc ttgattattc tcagcggtgg
    13561 aaaaatcagg cgtactcatt tattttcctc gttatgtttc agtgaaaatg tgcgatagca
    13621 gatgttaagg cggcggagta taccataagc tacgctaaaa atagcagtgg ttgttttttg
    13681 atcaaaaagc agaggggtta cccacaaaat aaacgttgcc gcgtgatgca tatattttct
    13741 tcattctttg tttattacgc gtattttact cgttaattat tgttacaaag ttgattccct
    13801 aattagtgtt tagacagcgg aacgtgaaat ttttgtcacc attatgaaat agcagcccgg
    13861 aacagcgccg tcagaagggg ctacaacgtt ggcagttgcc acatgacgta caacataatt
    13921 tccaaaaacg agagcaaaat cgaatacccg gtgttttttt acgtttcaaa gttgagataa
    13981 aaccagctaa tataagggcg attaactatc agtagcgtta tccctattct ggagatattc
    14041 ctttgatcaa cgttcttctt gttgatgacc acgaactggt gcgcgcaggg atacgacgca
    14101 ttcttgaaga tataaagggc attaaagttg tcggtgaagc gtgctgcgga gaggatgcgg
    14161 taaaatggtg ccgtactaac gccgttgacg tcgtgctgat ggatatgaac atgcccggta
    14221 ttggcggcct tgaggcgacg cgtaaaattg cccgatcgac agcggatatc aaagtgatca
    14281 tgctgaccgt ccatacggag aacccgttgc ccgccaaagt gatgcaggct ggcgcagctg
    14341 gctatctcag caaaggcgct gcgcctcagg aggtggtgag cgctattcgt tcggtgtatt
    14401 ccggacaacg ttatatcgcc tccgatatcg ctcaacagat ggcgctcagt cagattgagc
    14461 ctgcaaaaac ggaaacgccg ttcgccagtt tgtctgaacg cgagttgcag attatgctga
    14521 tgatcaccaa gggccagaag gtcaatgaga tttcagaaca gctgaatctc agtcctaaaa
    14581 cggtgaacag ctatcgctat cgtatgttca gtaaattaaa cattcatggt gatgttgagc
    14641 tgactcacct ggcaatccgc catggcctgt gtaatgcgga gacgttaaca agccagtgag
    14701 tgaaatattt gacgcaaagg cgttcctgaa aaccgttacc agccaacccg gtgtctatcg
    14761 tatgtatgac gccggcggta cggttatcta tgttggtaaa gcaaaagacc tgaaaaagcg
    14821 tctttccagc tactttcgca gcaacctggc ttcgcgtaaa accgaagcgc tagttgcgca
    14881 aattcaacac attgatgtca cggtaacgca taccgaaacg gaagcgctgc tgcttgagca
    14941 taattacatc aagttgtatc aaccgcgtta caacgtgttg ttgcgtgatg ataaatccta
    15001 tccttttatt tttctgagcg gcgataccca tccgcgtctg gcgatgcacc gtggcgccaa
    15061 acatgcgaaa ggcgagtact tcggtccatt tcctaatggc tatgccgtta gggaaacgct
    15121 ggcgctgtta cagaaaattt tccctatccg ccagtgcgaa aacagcgtgt atcgcaaccg
    15181 ctcgcgtcct tgcctgcaat accagattgg ccgctgctta ggcccctgcg ttgcaggact
    15241 ggtcagcgag gaggagtaca cgcaacaggt ggagtatgtc cggttgtttt tgtccggcaa
    15301 ggacgaccag gtcttaacac agctgattgc ccggatggaa aaggccagcc aggatttggc
    15361 atttgaagag gcggcgcgta ttcgcgatca gatccaggcg gtacgccggg tcacggagaa
    15421 acagtttgtc tccaatgcgg gcgacgatct cgacgttatc ggtgtggctt ttgatgcggg
    15481 tatggcctgt gtgcatgtgt tgtttattcg ccagggtaag gtactgggca gccgcagcta
    15541 ttttccaaaa gtgcctggcg gtacggaact gggcgaagtg gtggaaacct ttgtcgggca
    15601 gttttacctg cagggtagcc agatgcgcac gctaccgggc gagatactac tcgattttaa
    15661 tctgagcgat aaaacgctgc tggccgattc gttgtcggag cttgccggac ggcgtattca
    15721 tgtccagaca aaaccgcgcg gcgatcgcgc ccgctatctc aagctagcgc ggaccaacgc
    15781 ggcaacggcc ttagtcacta aactttcgca gcagtccacc atcacgcagc gtttgaccgc
    15841 gctggcgacg gtattaaaac ttcctgcgat caagcggatg gaatgttttg acatcagcca
    15901 taccatgggg gagcaaacgg tcgcatcctg tgtggtattt gacgctaacg ggccgttacg
    15961 cgccgagtat cgtcgttata atatcgcggg catcacgccg ggtgatgact acgcggcgat
    16021 gaatcaggtg ctacgtcggc gttatggcaa ggccatagaa gaaagtaaga ttccggatgt
    16081 tattctgatc gacggcggaa aagggcagct cgcccaggcg aaagccgttt tcgctgagct
    16141 ggatgtcccc tgggataagc atcgtccttt gctgctcggc gtcgccaaag gcgcggacag
    16201 aaaagccggt ctggaaacac tcttttttga accggaaggc gaggggttta gcctgccgcc
    16261 ggactcgccg gcgctgcatg ttattcagca tattcgcgat gagtcgcacg atcacgcgat
    16321 cggcgggcac cgtaaaaaac gcgcgaaggt taaaaatacc agtacgctgg aaactattga
    16381 aggcgttggg cctaaacgtc gccagatgct gctgaaatat atgggcggtt tgcaaggatt
    16441 acgtaacgcc agcgtagaag aaattgcaaa agtgccgggt atttcgcaag gtctggcaga
    16501 aaagatcttc tggtcgttga aacattgagg ccactgtagc aacatagggg taatttcact
    16561 gacaacagat agttacccgt cactatgcaa tttaatatcc ctacgttgct cacgctgttt
    16621 cgcgtcatcc tgattccatt ctttgtcgtg gtgttttatt tgccgttcgc ctgggcgccg
    16681 atggtcagcg cgctgatttt ctgtattgcc gcgattaccg actggtttga cggctttctg
    16741 gcgcgacgct ggaaccagag tacgcgtttc ggcgctttcc tcgaccccgt cgccgacaag
    16801 gtgctggtgg cgatcgccat ggtgctggtc accgagcatt atcatagctg gtgggtgacg
    16861 ttacctgcgg cgacgatgat cgcccgcgaa attattatct ctgctctgcg tgaatggatg
    16921 gcggagctgg gcaaacgcag tagtgtagcg gtctcctgga tcggtaaagt caaaactacc
    16981 gcgcagatgg tggcgctggc gtggctcttg tggcgtccga atatctgggt agagtatgcc
    17041 gggatcgcgc ttttctttgt cgcagcggtg ctaacattgt ggtccatgtt gcaatatttg
    17101 agcgctgcac gcggagattt gcttgatcag tgatcgtttc gccgcaaatt tcagcaaacg
    17161 atcgtgagtg acgaaaaata tcgttgactc agtgcgtcag gtaagtagaa tgcaacgcat
    17221 cggacggcag cactgattgc cagacgataa caaaatcaag cgattaacaa agttgcttga
    17281 tactgcggga atagctcagt tggtagagca cgaccttgcc aaggtcgggg tcgcgagttc
    17341 gagtctcgtt tcccgctcca gtttaaaagc attggcgtaa agcggatgct ggctgaaaag
    17401 ccaaaaaaat ttggcgcgtt aacaaagcgg ttatgtagcg gattgcaaat ccgtctagtc
    17461 cggttcgact ccggaacgcg cctccaattt ttcccgagcc cggatggtgg aatcggtaga
    17521 cacaagggat ttaaaatccc tcggcgttcg cgctgtgcgg gttcaagtcc cgctccgggt
    17581 accatgggaa agacaagaat aatcaaagca ataagcagtg tcgtgaaacc acctacgggt
    17641 ggtttttttg tgctttcagt ttgtatgccg accgcgagcg tgaactctcc agcgcgatac
    17701 acagtaaaaa acatcggtag cggcatttct gccagtacaa cagttatgtg ctaccgaccc
    17761 gcaagaactt atgcctggta aatactaaac gtcgggtaaa tcagccgata aaatccatta
    17821 atctctataa aaaatgctga tatgttttat gcctgcttta ttaaagagag taggtctgcc
    17881 agtgaaatat accgataatg caaaattatt tattagcttc attaatattg ggattgtaag
    17941 ttgcgctttg ctactttttt attttgtatg agcctgagag tgcaatcgta acctactctc
    18001 ttcccggtga gctttcctct tcgacatgtg atgcacataa ttttattggc tacgtcgatg
    18061 caaatgactt tgcagagtat ataaaaaaag tagaactgac gcgctacaat atgtattgtc
    18121 tgaaaaaaac aggggcaggc cagtggagta tttatgcaaa ttaaacgagt atataactgt
    18181 tcaggggtat tttctgcaca atttaattaa aggtagatag cgaactaata ttcatcacta
    18241 ggtaatgtga tccgcttcat gctttaatca cgttttgcaa tattgtctta ataacaggtc
    18301 aactacagat aatttcgggt tttcgtgaat ggcggttttg gtcagtctct atattatgct
    18361 ttccccgctt tacggagatg atgatgcaaa agaaaacctg ggccgtttta ttgataccat
    18421 tgtgcctcac cgcttgccac cagacgacca accgatcaac agccaaagat gaaattctca
    18481 cagggagcta tattgacccg acaaaaacac gctttccgtt agcggattat tcacagtcgg
    18541 ttgataaatg gatacctccg gactcggctg attacactat tccggttatt gatagtgcta
    18601 cccaacaacg ctactttagc gcactaaaat ctcattattt cggaatggac agtgaagcgc
    18661 actcgccgtg gaatgatttt tatattaccg cattgctgaa aaaaaacgca gcacaggccc
    18721 gggatgccag tattaagcag tttcttagcg acggcagtgc ttattggggg gaaaacttca
    18781 gactttatac ctctcgctgg aaagaggagg ttagagggaa tacggatacg cagattgaca
    18841 atatctatca tgcctcccgg cgaggcatta tggtcagaga aagtttagtc agagcgctgc
    18901 caacggacga cccgctcttt aacgatcccc gtcaggcggg cgaggggtac ccgtttgata
    18961 atttacaaat gtcttcgctg cgtcccggta cgccggtcta tacgctgacg aagagcaaag
    19021 accaacgctg gcaatatgtc gtttcaccag cggtaactgg ctgggttcac agtgaagata
    19081 ttgccagtac ggatcagaaa tttataacac agtgggtttt gctcgctcac aagcaactgg
    19141 gggcatttat caacgcgccg gtttctgtcc atgccgcagg cgtctattat ttcaccgggc
    19201 gaccgggtac tattttaccg ttccgacatc aacgggcggg ccagttcctg attgcggcgc
    19261 cagttcgcgg cagcaacggt cgcgcgttta tccattgggt ctggctaagc ggtaacgagt
    19321 ttacggctat gccgtggaaa atgacgccgg aaaatatcgc cgtgctaatg aaagcaatgc
    19381 acggcgcccc ctacggttgg ggaaatttta acttttataa tgattgttca gccgaagtcc
    19441 gcagcctgtt aatgccgttt ggcatattcc tgcccagaca ttcatccgcg caggtagagt
    19501 ctgctggacg ggtggtcgat cttagtcata aaaatcccca aatgcggatc gattatctca
    19561 ccagatacgg aaaagcgttt actacgctgg tctatattcc agggcatatt atgctgtata
    19621 tcggtaacac aaccatgaat gggcaggtcg tgccgatgac ttatcagaat atctggggat
    19681 tgcgcccaaa ccatgctaat agccggagca ttatcggtga ggcggtattt ttgccgttac
    19741 tgcgttttta tcctgaaaat cctgagctga tatcgctggc tggtaaggtt ctgtttaagc
    19801 ttggttatat agaataggtt gacaaactgt gttatcgcgg aagacatgat taaggcaacc
    19861 gtgcgcgtgg atataaagat agtatccctg taaactgtgt ctgaaaaaag tatacgctat
    19921 agtgcgggct gtttatttga aatactatct ggagctgatt ctggatgtga ttatgtgcct
    19981 cacacattga agtgagagtt attgttggcg gtatctggct ggaggctggg tggtaaaaag
    20041 acgtaattta ttgcatttta ataacggtgc ccggtcagag cgcgatcttg gggatctggt
    20101 cactaaagtt tttgagaaag cggcgaaaaa agaaccgcaa ccgctataca catttagcct
    20161 gccgttgctg agtgtgcaag atgagatccg tgtttactgt aagaaaaaaa tatcaaaata
    20221 gggtacgata cgctgtttat ggaaataacc ttttctgctg acagagaagc ggtagacgaa
    20281 ctcattaaac acttttttac tgaaaataag ctctatttga gagggcggtt ttatctgtcc
    20341 gcggcggtgg tataagttag catgagtata atatagcgag aaacctatct ctcacttttg
    20401 tgtggggcga gcgcttcctg gcggaaaatc tgcgccctga tcctcctttt gtgcgttaac
    20461 ttccggaatc ctcctcattt cgtgttaatc tggcccctga tggttgccat ccaaactgcc
    20521 tgcaaaaaaa ttatttttat ccgctgcaat gtaagaggcc tacaggcgga agtcatcact
    20581 gaggaaaagc attatgaaaa tggaaccatt aaacgagaac gagctggaat ggctggatga
    20641 tgtgctgacg aaatacaata ccgatcaggt cattttggat gtcgcggagc tggacggtct
    20701 gattactgcg gtactaagtt ctccgcgtcc catcgagccg gaacagtggc tggtcgcgat
    20761 atggggggga cccgcgtacg taccgcgctg gacatctgaa aaagaaatga cgcgatttat
    20821 ggatctggta ttccagcaca tggcggacac agccgcccgg cttgaagact atccagaaca
    20881 gttcgagccg ctgtttggcc tgcgagaagt tgatggccat gaattaacga ttgttgaaga
    20941 atggtgcttt ggttacatgc gcggagtgtc gctgtccgac tggtctgact tgccggatac
    21001 gctaaaaccg gcgctggaag cgattgcctt acacggcacg gaagaaaact ttgcgctgtt
    21061 ggataaaatg agcccggaag cgttcgataa aagcgttgac gctatccgta tcgcggcgct
    21121 tgagctgcat gcctggtgga tggcgcatcc gcacacgacg ccgctacaga tgccgataaa
    21181 agcggaggtg aaagtggggc gtaacgatcc ttgtccatgc gggagcggca aaaaatttaa
    21241 gcagtgctgc ctgcattaat ggctcgtaaa cggccatagc gtgatgatta tcgagcctgg
    21301 acggcgtccg ggcccggtaa tctttgcctg gcgttaacct ggatcgggca ggaaccccag
    21361 tgcgatcgaa aactggacgc caatcacgac aatgccgcag ataaacacca gcgccagcgc
    21421 tggcgtgccg cctgccacac gatatcccgc ctgagggctc tgtttacggc attgccagac
    21481 cagcatggca gggatgagta gtgccagcac tgccagcgct acgccggcat agcctaatgc
    21541 catcacaaat ccacgtgggt agaaaagcgc aaacgccagc ggcggcagaa aggtaatcag
    21601 cccggtttgc aggcgtccgg acaccgtact gcggcgctgg aatagatcgg ccaggtaatc
    21661 aaataatcct agcgctacgc ccagaaaaga ggtcgccagc gccagatcgg cgaacaggtg
    21721 gaccgccagt tcgacatgtg gcgaagcgac cacttctctg agcgcctgca gcaggccatt
    21781 taacccggca tggctggcca gtagccctct gaatgtcggc gagtcgatac ttcccagcgt
    21841 ggcgagctgc caaaaaatat aggccactag cggaatggcg ctacccgtca taaagaccca
    21901 acgcagccgg cgaatgttgc cgttcatata actcacaata ctcggtacgc ttccgtgaaa
    21961 accaaacgag gtgaaaatga ccggtatggc ggacaatgcc agcccctgct gtaaaggaag
    22021 cgtaagaaga tttactttat gaatatgtgg cgtgagcaac gcaagcatga tgaccagaaa
    22081 aatgatcttc gcgctaaaca ggaagcggtt aaaaaggtcg accagcgagg tgcccacaca
    22141 caccacccca ccggcaacaa aggtgaacag cagcaccccg gcagcgggcg agagcgtggc
    22201 gccaagccag ttattaatac tggatgccag taattctccg gctccggaaa tgtaggcggc
    22261 ggtgagcgca tacattaaga acatcatgct gaatcccgta agccactgtc cgtaacgtcc
    22321 aagatagcgt tttgccaacg agcccagccc ggtatccgcc ggaacatgtt gatatacttc
    22381 cagtaatagt agcgcggtat aacacatcag cgcccacaga ccaatcaaca atcccagcgt
    22441 gacgctgaaa ccaacgccag ccgctgccag cggcattgcc agcatcccgg cgccgatagt
    22501 ggtgcctgcc acgataaaaa tactgcccag agttctgttt ttcacgcttt ctactacccc
    22561 ggtaacaaag aacggtgata tccgcggcgc agggtaaggc attacgctat tttcgtcaaa
    22621 tggtcgttac aataggtgta ctggaaattt tacagttccg ggcataaaag cgaatatggg
    22681 aggagacgcg gacaaccgcc gcaaacctgc gctagcgcaa agtcgctcgc acaaggacac
    22741 attaggctac aagttttatt caggagggct tatggattcc attcacggtc acgaagtact
    22801 caacatgatg attgagtctg gcgagcagta cacgcatacc tcgctggagg cggcaataaa
    22861 agcgcgcttt ggcgagcggg cacgatttca cacctgttca gcatcagata tgacggcggc
    22921 ggaactggtc gcgtttctgg cggcgaaagg aaagtttatt gcggtggagg acggtttttc
    22981 aacgcatgag agtaaaatct gccgccatta atacgccacg gtgagagcgc gtctcaccgt
    23041 gtaaggacgt gctggattaa ttttgcgtat ccagggtgga gagttcttta tcaatgaaat
    23101 aaagcccttc gccgcttttt cccgccagcg ttaatttatc aataatagat ttgaacagtt
    23161 tttcttcttc atgctgttcc gccacatacc actgcaagaa attaaatgtc ggataatcct
    23221 ggctggtcat tgcggcatga gccagttcat taattttttg cgtaataagc tgctcatgct
    23281 cataggtcgc gcggaacagt tcatccagtg aggtgtactc agcgaagggc gaagaaacgc
    23341 tattaatgcg cggcaggctt ccggtatcgg taaggtagtc aaacaggcgc tgcatatgcg
    23401 tcatctcttc ttgcgcatgg cgacgaagaa atgcggccgc gccttcaaaa ctgtgatagc
    23461 tacaccacgc gctcatttgt tgatagagca gggaggagta caactccaga ttcatttgct
    23521 cattcagttt gtcgatcatt tctgttttca gcatggt
//
LOCUS       DAJVBX010000053        23457 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.053, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000053 DAJVBX010000000
VERSION     DAJVBX010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 23457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23457
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.053"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            7..1281
                     /locus_tag="OPV72_001813"
                     /pseudo
     CDS             7..1281
                     /locus_tag="OPV72_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122303.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Glu/Leu/Phe/Val dehydrogenase"
     gene            1495..3207
                     /locus_tag="OPV72_001814"
                     /pseudo
     CDS             1495..3207
                     /locus_tag="OPV72_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460752.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-trehalase"
     gene            complement(3270..3524)
                     /locus_tag="OPV72_001815"
     CDS             complement(3270..3524)
                     /locus_tag="OPV72_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HCR9914135.1"
                     /translation="MGIIAWIVFGLIAGVIAKLLMPGRDGGGFILTCILGIVGAVVGG
                     WLATMFGIGGSISGFNLHSFLVAVVGAIVVLVIFRLLRRG"
     gene            3693..4427
                     /gene="ycgR"
                     /locus_tag="OPV72_001816"
     CDS             3693..4427
                     /gene="ycgR"
                     /locus_tag="OPV72_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar brake protein YcgR"
                     /protein_id="HCR9914136.1"
                     /translation="MSGYNEQFLKKNPLAILGVLRDLNKNQVPLRISWAHGQFISKIL
                     AVAPEKLIVDYGSQEYKNSAVLRAGQVAIIAETQGAKVEFTLPQLVTGEYQRLPAFIT
                     PLPSSLWFVQRREYFRIGAPLYPPYYGVTTLPDTRTLRFRLFDLSLGGMGALLESAIP
                     DGLIEGARFSQVELNMGPWGILHVDAQLLAISERKVIDGKNETITTPRLSFRFLNVSP
                     AVERELQRIIFSLERDARERANKVRE"
     gene            complement(4441..5052)
                     /gene="emtA"
                     /locus_tag="OPV72_001817"
     CDS             complement(4441..5052)
                     /gene="emtA"
                     /locus_tag="OPV72_001817"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane-bound lytic murein transglycosylase
                     EmtA"
                     /protein_id="HCR9914137.1"
                     /translation="MKLRWFAFLVVILAGCSSKQDYRNPPWNAEVPVKRAMQWMPISE
                     KAGAAWGVDPHLITAIIAIESGGNPNAVSKSNAIGLMQLKASTSGRDVYRRMGWRGEP
                     TTSELKNPERNISMGAAYLSILENGPLAGIKDPQVMQYALVVSYANGAGALLRTFSSD
                     RKKAIEKINDLDADEFFEHVVDNHPAPQAPRYIWKLQQALDAM"
     gene            5223..6137
                     /gene="ldcA"
                     /locus_tag="OPV72_001818"
     CDS             5223..6137
                     /gene="ldcA"
                     /locus_tag="OPV72_001818"
                     /EC_number="3.4.17.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="muramoyltetrapeptide carboxypeptidase"
                     /protein_id="HCR9914138.1"
                     /translation="MSLFHLIAPSGYCINQQAALRGVQRLTDAGHQVENDEVIRRRYQ
                     RFAGTDAERLADVNSLASLTSPDTIVMPVRGGYGASRLLDRIDWQALASRQQRDPLLI
                     CGHSDFTAIQAGLLAQANVITFSGPMLAANFGAETLNTFTEQHFWLALRKAQFTVEWQ
                     GDGPQCDVQGTLWGGNLAMLISLIGTPWMPTIDKGILVLEDVNEHPFRVERMLLQLEY
                     AGILNRQSAIVLGSFSGAAPNEYDAGYSLESVYAFLRSRLSVPLITGLDFGHEQRTVT
                     LPIGANATLKNTRQGTQLTLSGHPTLQL"
     gene            6234..7967
                     /locus_tag="OPV72_001819"
     CDS             6234..7967
                     /locus_tag="OPV72_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HCR9914139.1"
                     /translation="MDAATIISLFILGSILVTSSILLSSFSSRLGIPILVIFLAIGML
                     AGVDGIGGIPFDNYPFAYMVSNLALAIILLDGGMRTQASSFRVALGPALSLATLGVLI
                     TSGLTGMMAAWLFHLDLIEGLLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGS
                     NDPMAVFLTITLIEMIQKHETGLDWMFAVHIIQQFGLGIVFGLGGGYLLQQMINRISL
                     PSGLYPMLALSGGILIFALTTALEGSGILAVYLCGFLLGNRPIRNRYGILQNFDGLAW
                     LAQIAMFLVLGLLVTPSDLWPIAVPALILSIWMIFFARPLSVFTGLLPFRGFNLRERI
                     FISWVGLRGAVPIILAVFPMMAGLENARLFFNVAFFVVLVSLLLQGTSLSWAAKRAKV
                     VVPPVGWPVSRVGLDIHPDNPWEQFIYQLSADKWCVGAALRDLHMPNETRIAALFRNN
                     ELFHPTGSTRLQEGDVLCVIGRERDLPALGKLFSQSPPVSLDQRFFGDFILEANAKFA
                     DVALIYGLEEGTEYRDKQQTLGEIIQQLLGAAPVVGDQVEFGGMIWTVAEKEDNVVRK
                     IGVRVAEDEAE"
     gene            complement(8029..9099)
                     /gene="dadX"
                     /locus_tag="OPV72_001820"
     CDS             complement(8029..9099)
                     /gene="dadX"
                     /locus_tag="OPV72_001820"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolic alanine racemase DadX"
                     /protein_id="HCR9914140.1"
                     /translation="MTRPIQASLDLQVMKQNLAIVRRAAPEARVWSVVKANAYGHGIE
                     RVWSALGATDGFAMLNLEEAITLRERGWKGPILMLEGFFHAQDLEAYDTYRLTTCIHS
                     NWQLKALQNARLNAPLDIYVKVNSGMNRLGFQPERAQTVWQQLRAMRNVGEMTLMSHF
                     AQADHPEGIGEAMRRIALATEGLQCAYSLSNSAATLWHPQAHYDWVRPGIILYGASPS
                     GQWRDIADTGLKPVMTLSSEIIGVQTLSAGERVGYGGGYSVTQEQRIGIVAAGYADGY
                     PRHAPTGTPVLVDGIRTRTVGTVSMDMLAVDLTPCPQAGIGTPVELWGKEIKVDDVAS
                     AAGTLGYGLLCAVAPRVPFVTT"
     gene            complement(9113..10411)
                     /locus_tag="OPV72_001821"
     CDS             complement(9113..10411)
                     /locus_tag="OPV72_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-amino acid dehydrogenase"
                     /protein_id="HCR9914141.1"
                     /translation="MRVVILGSGVVGVTSAWYLSQAGHDVTVIDRESGPAQETSAANA
                     GQISPGYAAPWAAPGVPLKAIKWMFQRHAPLAVRLDGTPFQLKWMWQMLRNCDTRHYM
                     ENKGRMVRLAEYSRDCLKTLRAATGIEYEGRQGGTLQLFRTAQQYENATRDIAVLEDA
                     GVPYQLLEASRLAEVEPALAEVAHKLTGGLRLPNDETGDCQLFTQRLARMAEQAGVTF
                     RFNTPVEKLLYENDQIYGVKCADEIIKADAYVMAFGSYSTAMLKGIVDIPVYPLKGYS
                     LTIPIVEPDGAPVSTILDETYKIAITRFDKRIRVGGMAEIVGFNTDLLQPRRETLEMV
                     VRDLFPRGGHIEQATFWTGLRPMTPDGTPVVGRTRYKNLWLNTGHGTLGWTMACGSGQ
                     LLSDILLGRTPAIPYDDLSVARYRSDFTPTRPQRLHSAHN"
     gene            10734..12266
                     /locus_tag="OPV72_001822"
     CDS             10734..12266
                     /locus_tag="OPV72_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460760.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoVR family protein"
                     /protein_id="HCR9914142.1"
                     /translation="MAMIDSMNKDTTRLSDGPDWTFDLLDVYLAEIDRVAKLYQLDTY
                     PHQIEVITSEQMMDAYSSVGMPINYPHWSFGKKFIETERLYKHGQQGLAYEIVINSNP
                     CIAYLMEENTITMQALVMAHACYGHNSFFKNNYLFRSWTDASSIVDYLIFARNYITRC
                     EERYGVDEVEKLLDSCHALMNYGVDRYKRPQKISLQEEKARQKSREEYLQSQVNMLWR
                     TLPKREEEKTVAEARRFPAEPQENLLYFMEKNAPLLEPWQREILRIVRKVSQYFYPQK
                     QTQVMNEGWATFWHYTILNHLYDEGKVTERFMLEFLHSHTNVVFQPPYNSPWYSGINP
                     YALGFAMFQDIKRICQSPTDEDKYWFPDIAGSDWLETLHFAMRDFKDESFISQFLSPK
                     VMRDFRFFTVLDDDRHNYLEISAIHNEEGYREIRSKLSSQYNLSNLEPNIQVWNVDLR
                     GDRSLTLRYIPHNRAPLDKGRKEVLKHVHRLWGFDVMLEQQNEDGSVELLERCPPRMN
                     TL"
     gene            complement(12313..13032)
                     /gene="fadR"
                     /locus_tag="OPV72_001823"
     CDS             complement(12313..13032)
                     /gene="fadR"
                     /locus_tag="OPV72_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid metabolism transcriptional regulator
                     FadR"
                     /protein_id="HCR9914143.1"
                     /translation="MVIKAQSPAGFAEEYIIESIWNNCFPPGTILPAERELSELIGVT
                     RTTLREVLQRLARDGWLTIQHGKPTKVNNFWETSGLNILETLARLDHESVPQLIDNLL
                     SVRTNISTIFIRTALRQHPDKAQEVLATAHEVADHADAFADLDYNIFRGLAFASGNPI
                     YGLILNGMKGLYTRIGRHYFANPEARSLALGFYHKLSSLCEQGAHDQVYETVRRYGHD
                     SGEIWHRMQKNLPGDLAIQGR"
     gene            13252..14796
                     /gene="nhaB"
                     /locus_tag="OPV72_001824"
     CDS             13252..14796
                     /gene="nhaB"
                     /locus_tag="OPV72_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na(+)/H(+) antiporter NhaB"
                     /protein_id="HCR9914144.1"
                     /translation="MEISWGRAMWRNFLGQSPDWYKLALLVFLIVNPFIFLANPFVAG
                     WLLVAEFIFTLAMALKCYPLLPGGLLAIEAVIIGMTSAAHVREEVAANLEVLLLLMFM
                     VAGIYFMKQLLLFIFTRLLLSIRSKMVLSLAFCVAAAFLSAFLDALTVVAVVISVAVG
                     FYGIYHRVASSRGEENDMLDDSHIDPHYKTVLEQFRGFLRSLMMHAGVGTALGGVMTM
                     VGEPQNLIIAKAAGWHFGDFFLRMSPVTVPVLVCGLLTCMLVEKMRWFGYGETLPEKV
                     RDVLQQFDDQSRKKRTRQDKIKLIVQAVIGVWLVTALALHLAEVGLIGLSVIILATAL
                     TGVTDEHAIGKAFTESLPFTALLTVFFSIVAVIIDQHLFAPIIQFVLQASEHAQLTLF
                     YLFNGLLSSISDNVFVGTIYINEAKAAMENGAISLKQFELLAVAINTGTNLPSVATPN
                     GQAAFLFLLTSALAPLIRLSYGRMVWMALPYTIVLTLIGLLCVEFTLAPATEWMTQAG
                     WLATLS"
     gene            14938..15468
                     /gene="dsbB"
                     /locus_tag="OPV72_001825"
     CDS             14938..15468
                     /gene="dsbB"
                     /locus_tag="OPV72_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="disulfide bond formation protein DsbB"
                     /protein_id="HCR9914145.1"
                     /translation="MLRFLNQCSRGRGAWLLMAFTALALEMVALWFQHVMLLKPCVLC
                     IYERCALFGVMGAGLVGAIAPKTPLRYVAMVIWIYSAWRGLQLAYEHTMIQLHPSPFM
                     TCDFMARFPDWLPLGKWLPQVFVASGDCAERQWSFLTLEMPQWLLGIFAAYLVVAIAV
                     VIAQAFKPKKRDLFGR"
     gene            15576..15917
                     /locus_tag="OPV72_001826"
     CDS             15576..15917
                     /locus_tag="OPV72_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1971 domain-containing protein"
                     /protein_id="HCR9914146.1"
                     /translation="MSHLRIPANWKVKRSTPFYTKENVPAALLSHHNTAAGVFGQLCV
                     MEGTVTYYGFANETATEPEVKVVINAGQFATSPPQYWHRVELSDDARFNIHFWVEEDH
                     QGEEMYQQKKA"
     gene            complement(15989..16162)
                     /locus_tag="OPV72_001827"
     CDS             complement(15989..16162)
                     /locus_tag="OPV72_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module toxin, GnsA/GnsB family"
                     /protein_id="HCR9914147.1"
                     /translation="MNSEELTHKAEEEIAALISKKVAELRKKTGQEVSEIEFAPRETM
                     KGLEGYHVKIKLL"
     gene            complement(16354..16491)
                     /locus_tag="OPV72_001828"
     CDS             complement(16354..16491)
                     /locus_tag="OPV72_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914148.1"
                     /translation="MSERPDLVDPLPEDEPLPGENIPDTPEGDDPLDPDTQNEVEDPR
                     R"
     gene            complement(16843..17289)
                     /locus_tag="OPV72_001829"
     CDS             complement(16843..17289)
                     /locus_tag="OPV72_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309703.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcgN family cysteine cluster protein"
                     /protein_id="HCR9914149.1"
                     /translation="MSDTPFWQRKTLDEMTDAEWESLCDGCGQCCLHKLMDEDTDEIY
                     FTNVACRQLNIKTCQCRHYERRFEFEPDCIKLTRENLPDFEWLPMTCAYRLLAEGKPL
                     PTWHPLQTGSKAAMHGERISVRHIAVKESEVRDWQDHILNKPSWAE"
     gene            complement(17382..18041)
                     /locus_tag="OPV72_001830"
     CDS             complement(17382..18041)
                     /locus_tag="OPV72_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HCR9914150.1"
                     /translation="MYQHRNWQGALLDYPVSKVVCVGSNYANHIKEMGSATPEEPVLF
                     IKPETALCDIRQPLAIPADMGAVHHEVELAVLIGATLRQATEDHVRKAIAGYGVALDL
                     TLRDIQGKMKKAGQPWEKAKGFDNACPISGFIPVAAFCGDPQNTVIGLNVNGEVRQQG
                     STADMIHPIVPLIAYMSRYFTLKAGDVVLTGTPAGVGPLLSGDELDIRFNGETLSTRV
                     L"
     gene            complement(18091..18384)
                     /locus_tag="OPV72_001831"
     CDS             complement(18091..18384)
                     /locus_tag="OPV72_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001667868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcgL domain-containing protein"
                     /protein_id="HCR9914151.1"
                     /translation="MFCVIYRSSKRDQTYLYVEKKDDFSRVPDALMKGFGQPQLAMML
                     PLDGRKKLVNAELEKVKQALSEQGYYLQLPPPPEDLLKQHLSSVGQNTSHADR"
     gene            18510..19217
                     /gene="minC"
                     /locus_tag="OPV72_001832"
     CDS             18510..19217
                     /gene="minC"
                     /locus_tag="OPV72_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinC"
                     /protein_id="HCR9914152.1"
                     /translation="MSNTPIELKGSSFTLSVVHLHEAEPEVIRQALEDKIAQAPAFLK
                     HAPVVINVSGLESPVNWPELHKIVTSTGLRIIGVSGCKDASLKVEIDRMGLPLLTEGK
                     EKAVRPAPVEPATPSEPPQNANPITKTRLIDVPVRSGQRIYAPQCDLIVTSHVSAGAE
                     LIADGNIHVYGMMRGRALAGASGDREAQIFCTHLTAELVSIAGVYWLSDKIPAEFYGK
                     AARLRLADNALTVQPLN"
     gene            19241..20053
                     /gene="minD"
                     /locus_tag="OPV72_001833"
     CDS             19241..20053
                     /gene="minD"
                     /locus_tag="OPV72_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020801817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinD"
                     /protein_id="HCR9914153.1"
                     /translation="MARIIVVTSGKGGVGKTTSSAAIATGLAQKGKKTVVIDFDIGLR
                     NLDLIMGCERRVVYDFVNVIQGDATLNQALIKDKRTENLFILPASQTRDKDALTREGV
                     AKVLDSLKAMDFEFIVCDSPAGIETGALMALYFADEAIITTNPEVSSVRDSDRILGIL
                     ASKSRRAENGEEPIKEYLLLTRYNPGRVNKGDMLSMEDVLEILRIKLVGVIPEDQSVL
                     RASNQGEPVILDATADAGKAYADTVDRLLGEERPFRFIEEEKKGFLKRLFGG"
     gene            20057..20323
                     /gene="minE"
                     /locus_tag="OPV72_001834"
     CDS             20057..20323
                     /gene="minE"
                     /locus_tag="OPV72_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division topological specificity factor
                     MinE"
                     /protein_id="HCR9914154.1"
                     /translation="MALLDFFLSRKKSTANIAKERLQIIVAERRRSDAEPHYLPQLRK
                     DILEVICKYVQIDPEMVTVQLEQKDGDISILELNVTLPEAEESK"
     gene            complement(20445..21572)
                     /gene="rnd"
                     /locus_tag="OPV72_001835"
     CDS             complement(20445..21572)
                     /gene="rnd"
                     /locus_tag="OPV72_001835"
                     /EC_number="3.1.13.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease D"
                     /protein_id="HCR9914155.1"
                     /translation="MNYQMIETDDALASLCEAVRACPAIALDTEFVRTRTYYPQLGLI
                     QLFDGANVALIDPLGISDWSPLKAVLRDTGITKFLHAGSEDLEVFLNAFGELPEPLID
                     TQILAAFCGRPLSWGFASMVEEYTGVALDKSESRTDWLARPLSERQCEYAAADVWYLL
                     PIAKKLMIETEAAGWLPAALDECRLMQQRRQEIQAPEEAWRDITNAWQLRTRQLACLQ
                     LLADWRLRKARERDMAVNFVVREENLWAVARYMPGSLGELDSLGLSGSEIRFHGKTLI
                     SLVAKAQALPEEALPEPLLNLMDMPGYRKAFKAIKALVAEVSASHHVSGELLASRRQI
                     NQLLNWHWKLKPQNGQPELISGWRAELMAEKLTLLLQEYSL"
     gene            complement(21645..23330)
                     /gene="fadD"
                     /locus_tag="OPV72_001836"
     CDS             complement(21645..23330)
                     /gene="fadD"
                     /locus_tag="OPV72_001836"
                     /EC_number="6.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="long-chain-fatty-acid--CoA ligase FadD"
                     /protein_id="HCR9914156.1"
                     /translation="MKKVWLNRYPADVPAEINPDRYQSLVELFEHAATRYADQPAFVN
                     MGEVMTFRKLEERSRAFAAYLQQGLGLKKGDRVALMMPNLLQYPVALFGILRAGMIVV
                     NVNPLYTPRELEHQLNDSGAAAIIIVSNFAHTLEKVVEKTSVQHVILTRMGDQLSTAK
                     GTVVNFVVKYIKRLVPKYHLPDAISFRSALQHGYRMQYVKPEVVAEDLAFLQYTGGTT
                     GVAKGAMLTHRNMLANLEQVKATYGPLLHPGKELVVTALPLYHIFALTMNCLLFIELG
                     GQNLLITNPRDIPGLVKELAKYPFTAMTGVNTLFNALLNNKEFQQLDFSSLHLSAGGG
                     MPVQNVVAERWVKLTGQYLLEGYGLTECAPLVSVNPHDIDYHSGSIGLPVPSTEAKLV
                     DDDDNEVAPGEAGELCVKGPQVMLGYWQRPDATDEIIKDGWLHTGDIAVMDEDGFLRI
                     VDRKKDMILVSGFNVYPNEIEDVVMQHSGVQEVAAVGVPSGSSGEAVKLFVVKKDPAL
                     TDDALITFCRRHLTGYKVPKQVEFREELPKSNVGKILRRELRDEARGKVDNKA"
BASE COUNT         5431 a         6306 c         6012 g         5708 t
ORIGIN      
        1 tttatcatgg ataagttatc ttacgcttca gatagcagca catctgcctg gaatacctac
       61 ctgcaacaaa tcgagcgtgt ggccccttat ctgggcgagt tatcccccta ggtggatact
      121 ctgcgccacc caaaacgcgc tctgatcgtc gatattccgg tacaaatgga tgatggcact
      181 attcgtcatt tcgaaggata tcgcgtgcag cacaacctct cccgaggtcc gggtaaaggc
      241 ggtgttcgct accatcctga cgttgatctc aatgaagtga tggccctgtc agcatggatg
      301 accatcaaat gtgccgcgct gaatctgccg tacggcggcg ccaaaggcgg catccgcgtc
      361 gatccgttct cgctgtcgga aggtgaactg gagcgtttga cccgccgcta taccagcgag
      421 atcggcatta tcatcgggcc gcagaaagat attcctgcgc cggatgtcgg caccaacggt
      481 aaagtgatgg cctggatgat ggatacgtat tccatgaatc atggcacgac ggtcactggc
      541 gtcgtcaccg gtaagcctat ccatcttggc ggttcgctgg gtcgtgaaaa ggcgacgggg
      601 cgcggcgttt tcgtcagcgg gctggaagcc gcgcgtcggg cgaatatcgc cgttgaaggc
      661 gctcgcgttg cggttcaggg ttttggtaac gtcggcagcg aagccgcgcg tctgtttgca
      721 ggcgctggcg cccgtgtcgt ggcgattcag gatcataccg cgacgctgtt taacgccacc
      781 ggtattgaca tgaaggcgct cacggcatgg cagacagaac acaaacagat agccggtttc
      841 ccgggcgcgg aaactatcgc cagcgatgcg ttctggcgtc tggagatgga tattctgatc
      901 ccggcggcgc ttgaaggcca gataactcgt cagcgcgcgg aagccctgac gtgtaagctg
      961 gtgctggaag gggctaacgg cccgacctat ccggatgctg atgatgttct ggccagccgt
     1021 ggtatccttg tggtgcctga cgtggtctgt aacgcaggcg gcgtaaccgt cagctacttc
     1081 gaatgggtac aagatatggc cagcttcttc tggagcgaag aagagatcaa cgcgcgcatg
     1141 gacaaaatca tgaccgacgc gatcgtccat gtctgggaga aagcggctga gaaatcctgt
     1201 tctctgcgca ccgcagccta tattgtcgcc tgtgagcgca ttctgctggc ccgtaaagat
     1261 cgcggtatct atccaggtta aggcgacaaa tcattgcgct aaaatccacg tcccggcgtg
     1321 gattttttgt ctgtataccc cgttttccac gcgcgcgccg ataaattctg tctcaataaa
     1381 atgtctgttt gttcgcaaaa tagcggttca atcacgcgta tctggtcatc gtagactaag
     1441 gttttgtcat ggtaaatgcc gttggctttg gctcactgct aaggagataa cttgatgata
     1501 cccccagaga ttcgccgttc tgttctacta cagaaagcca taaaactggc gctggcaggg
     1561 acgctgctga cgtttgcatc gttttcggcg actgccgcag acccgtcttc cgacactgaa
     1621 actccgcagc cgccggatat tttgcttggc ccgctcttta atgatgtcca gaatgcaaaa
     1681 ctcttccccg atcagaaaac ctttgctgac gccataccta atagcgatcc gctcatgatt
     1741 cttgcggatt atcgtatgca gcggaactag tccggcttcg atttgcgtca ttttgttgat
     1801 gttaacttca ccctgccgaa agcgggtgaa aaatatgtcc cgcctgccgg gcaatcattg
     1861 cgtgaacata ttgatggcct gtggccggtg ctgacccgtt caactaaaaa cgtcgaaaag
     1921 tgggactcgc tcttgccgtt gcctgaatcc tatgtcgtac cgggtgggcg attcagggag
     1981 atttactact gggacagcta ctttacgatg ctggggctgg cggaaagcgg gcactgggat
     2041 aaggtggcgg atatggtagc gaactttggt tacgaaattg acgcctgggg gtatattcct
     2101 aacggcaacc gtacctacta cctgagtcgt tcacagccgc ctttctttgc gtttatggtt
     2161 gaattactgg tgcaacatga aggtgacgat gcgctgaaag aatacctgcc gcaactgcaa
     2221 aaagagtacg cctactggat ggagggcgtt gagacattgc agccagggca acaaaaccaa
     2281 cgcgtcgtca aactggagga cggcagcgtt ctcaaccgct actgggacga tcgggatacg
     2341 ccccgccctg aatcctgggt tgaagatatc gctaccgcca aaagcaaccc cagccgcccg
     2401 gcaacggaga tctatcgaga cctccgatct gctgccgcct ccggctggga tttcagctcc
     2461 cgctggatgg ataatccgca gcagctcagt accattcgta ccaccacgat tgtccctgtc
     2521 gatcttaacg ctctgctgta tcagctggag aaaaccctcg cccgcgccag cgctgcggcg
     2581 ggcgatcggg ccaaagcctc gcaatatgac gcgctggcca acgcgcggca aaaagccatt
     2641 gaaatgcatc tgtggaataa caaagagggt tggtatgccg actacgatct gcagaacaat
     2701 aaaatccgtg accaactcac cgctgccgcg ctgttcccgc tctatgtaaa cgccgccgcg
     2761 aaagatcgcg ccgcgaaagt ggcagcggcg gcccaggcgc atctgctaca gcctggcggg
     2821 ctggctacca cctcggttaa aagcggacag cagtgggatg cgccaaatgg ctgggcgccg
     2881 ttacaatggg tcgctgccga aggattgcaa aattatgggc aggatgacgt ggcaatggaa
     2941 gtcacctggc gctttttaac caatgtgcag cacacctacg atcgcgagaa aaaactggtc
     3001 gaaaaatatg acgtcagcag taccggaacc ggcggtggcg gcggcgaata tccccttcag
     3061 gacggctttg gctggagcaa cggcgtgacg ctgaaaatgc tcgatctgat ttgtccgcag
     3121 gaaaaaccgt gcgatagcgt accgtctact cgtccggcat cgttaagcgc aacgccgaca
     3181 aaaacgccgt ctgcagcgac gcagtaacgc gtgtttatag taggttgacc cggcgctgac
     3241 cgggtcaacg cttacacgtt ctgcagcggt tagccgcgtc gcagaaggcg gaaaatcacc
     3301 agcaccacaa tcgcgcccac cacggcgacc aggaaactgt gcagattaaa gccgctgata
     3361 ctgccgccaa taccaaacat cgtcgccagc catccgccaa cgaccgcccc gacgataccg
     3421 agaatacagg tcaggataaa tcccccgcca tcgcgccccg gcataagcaa tttggcgata
     3481 acgccggcaa tcaaaccaaa aacaatccag gcgataattc ccatttgcga accctctttc
     3541 cagtaaaaac gttttaagta taggcaaagt cgagcgtcgc atttctgaac actgatttat
     3601 ctcgcggaca taaaaattta tttatcgcta ttaagttctt tctactgatg ccgataaccc
     3661 aacgatagtc tgcgtatcag gggttatttc gtgtgagtgg ttacaatgag cagttcctga
     3721 aaaaaaatcc attagcgata ttaggcgtgc tacgggattt aaataaaaat caggttccac
     3781 tgcgtatttc atgggcgcat ggtcaattca ttagtaaaat tttggcggta gccccggaaa
     3841 aactcatcgt ggattacggc agccaggaat ataaaaatag cgccgtatta cgcgccgggc
     3901 aggtagccat tatcgcagaa acacaaggcg caaaagtcga gttcacgttg ccgcaactcg
     3961 ttacaggtga atatcagcgg ctgccggcct ttatcacgcc cctgccgtca tcactgtggt
     4021 ttgtccagcg ccgggagtat tttcgcattg gcgcgccgct gtatccgcct tattacggcg
     4081 tcaccacgct accggacacc cgtacgttac gttttcgcct gtttgatctt tccctgggcg
     4141 gcatgggcgc gctactggaa tccgccatcc ccgacggact aatcgaaggc gcacgctttt
     4201 cgcaggttga actgaacatg gggccatggg ggattcttca cgttgacgcc cagcttctcg
     4261 ccatcagcga gcgtaaggtg attgatggga aaaatgaaac gatcaccact ccccgcctga
     4321 gctttcgttt ccttaacgtt agcccggcgg tggagcggga gttgcagcgg attatttttt
     4381 cgcttgagcg cgacgcccga gaaagagcga ataaagtgcg agaataatct tcacgctaaa
     4441 ctacatggcg tccagcgcct gctgaagctt ccagatatag cgcggcgcct gcggcgcggg
     4501 atgattatca acaacatgtt caaaaaactc gtcagcatcc agatcgttaa ttttttctat
     4561 cgccttcttc ctgtcggatg aaaaagtacg caataacgcg cctgcgccgt tagcataaga
     4621 gacgaccagc gcatattgca tcacctgcgg atctttgatg ccggccagcg gcccattttc
     4681 cagaatgctc agatacgccg cgcccattga gatgttacgc tcagggtttt tcagctcgct
     4741 ggtggtcggt tcgccacgcc agcccatacg acggtaaacg tcgcgcccgg aagtcgacgc
     4801 ctttaactgc atcaggccaa tcgcattgga cttactgacc gcgttagggt tgccgccgga
     4861 ttcaatggcg ataatcgcgg tgattaaatg tggatcaacc ccccatgccg ccccggcttt
     4921 ttcactgatg ggcatccact gcatcgcacg ctttacaggc acttcggcat tccacggtgg
     4981 attcctgtaa tcctgttttg agctacagcc agccagtatt actaccaaaa aagcaaacca
     5041 tcttaatttc acgtcatcta tccttatagc cgtaacttat ctgccgaaga ggttataccg
     5101 ccccggccag gtacttaggt tgcctccctg gtgcgcatcc agaaacgtcg cacaacgagg
     5161 gacatcgcct aatatatgcg gcatgatata catttgcatt ctattgtcag caaggaatta
     5221 ccatgtctct gtttcattta atcgccccct cgggctactg tattaaccaa caggccgcgt
     5281 tacgcggcgt tcagcgcctg actgacgcgg gtcatcaggt ggagaatgac gaggtgattc
     5341 gtcgccgcta tcagcgtttt gccggtacgg acgcggaacg gctggccgat gttaattcgc
     5401 tggcctcgct aacttcgccg gatacgatcg tcatgccggt tcgcggcggc tatggcgcca
     5461 gccgcttgct ggatcgtatc gactggcagg cgctcgcctc ccggcaacag cgcgatccct
     5521 tactgatttg cggtcatagc gattttacgg cgattcaggc tggactactg gcgcaggcca
     5581 atgtcatcac ctttagcggt cctatgctgg cggcaaattt tggcgccgaa acgctgaata
     5641 cgttcaccga gcaacatttc tggctggcgc tacgcaaggc gcaatttacc gtagagtggc
     5701 aaggcgacgg ccctcagtgc gacgtacagg gcaccttatg gggcggaaat ctggcgatgt
     5761 tgatttccct tatcggtacg ccctggatgc cgactatcga taaaggaatt ttagtgctgg
     5821 aagatgtcaa tgagcatcct ttccgggtgg agcgtatgct tttgcaactg gagtacgccg
     5881 gaattctaaa ccgtcagagc gccatcgttc tcggcagctt tagcggcgcg gcgcccaacg
     5941 agtatgacgc cggctattct ctggagagcg tctacgcgtt tttacgttcc cgtctgtccg
     6001 ttccgctgat taccggtctc gacttcgggc atgaacagcg tacggtgacg ctccctatcg
     6061 gggcaaacgc aacgcttaaa aatacgcgcc aggggactca actcacttta tctggtcatc
     6121 ctacgctgca attgtaaaaa aagtccccga caggctaagt aaaacgctgc cctggccgtt
     6181 attatgttaa tgttaaataa tacgaagtcg tgtgagtcag gagatataaa acgttggatg
     6241 ctgcaacaat tattagtcta tttattttag gttccatcct tgtaaccagc agtatcctgt
     6301 taagttcatt ctcatcgcga ctgggtatcc cgattctggt cattttcctc gccattggga
     6361 tgttagcggg tgtggatggc attggcggta ttcctttcga taattatcct ttcgcttata
     6421 tggtcagtaa cctggcgctg gcgattattt tactcgatgg cggcatgcgc acccaggcca
     6481 gctctttccg ggtagcgctg ggccccgcgc tgtcgctggc gacgctcggc gtactgatca
     6541 cgtcggggtt aacaggtatg atggccgcct ggctgtttca tctggatctt atcgaaggtc
     6601 tgcttatcgg cgcgatagtc ggttccactg acgccgcagc ggtcttttct ctgcttggcg
     6661 gcaaagggct aaacgaacgt gtaggctcca cgctggagat cgaatcggga agtaacgacc
     6721 cgatggccgt ttttttgacc attacattaa ttgagatgat ccagaaacat gaaaccggcc
     6781 tggactggat gtttgccgtc catattatcc agcagttcgg tctcggtatt gtttttggcc
     6841 tcggcggcgg ttacctgcta cagcagatga tcaaccgtat ttctctgccc agcggcctgt
     6901 atccgatgct ggcgctcagc ggcggtattc tgatttttgc tttgacgacc gcgcttgaag
     6961 gcagcggcat tctcgcggtc tatctgtgcg gattcctgtt aggaaaccgt ccgattcgca
     7021 accgttacgg catcctgcaa aactttgacg gactggcctg gctggcgcag atcgccatgt
     7081 tcctggtcct gggactgctg gtgacgcctt ccgatctgtg gccgattgcc gtccctgcgc
     7141 ttattctctc tatctggatg attttcttcg cccgcccatt gtcggtattt accggcctgc
     7201 tgccttttcg cggcttcaat cttcgggagc gcattttcat cagttgggtc ggactgcgcg
     7261 gcgcggtgcc gattattctc gccgttttcc cgatgatggc cgggcttgaa aacgctcgcc
     7321 tgttctttaa tgtcgctttc tttgtggtac tggtgtcgct gctcctgcag ggaacatcgc
     7381 tgtcatgggc ggcgaagaga gccaaagtgg tcgtgcctcc ggttggctgg ccagtatcgc
     7441 gcgtggggct tgacatccat cctgataatc cgtgggaaca attcatctat cagttgagcg
     7501 ccgacaaatg gtgcgtcggc gcggcgttgc gcgacctgca tatgccgaac gaaacccgca
     7561 ttgccgcgct atttcgcaat aatgaactgt ttcaccccac gggtagcact cgcctgcagg
     7621 aaggcgacgt actctgcgtg attggccggg agcgcgatct gccagcgctg ggcaaattgt
     7681 ttagccagtc gccgccggtt tcgttagatc agcgtttctt tggcgatttt atcctcgaag
     7741 cgaacgcgaa attcgccgac gtggcgctta tctacgggct ggaagaagga acggaatacc
     7801 gggataaaca acaaaccctc ggtgaaatca tacagcagct gctgggcgct gcgccggtcg
     7861 ttggcgatca ggtggagttt ggcggcatga tttggacggt agctgaaaaa gaagataacg
     7921 tggtacgcaa gattggggta cgcgtcgccg aagacgaagc agaataaggt cgccggacaa
     7981 cgtcgacccg cccccggtgg accggtcgac gccttagcct gagttaggtt acgttgtcac
     8041 aaacggcacg cgcggcgcta cggcgcacag tagcccatag cccagcgtgc ctgccgcaga
     8101 ggcgacatca tcgaccttaa tttctttgcc ccataattca accggcgtgc cgattcccgc
     8161 ctgcggacac ggcgtcaaat ccaccgccag catatccatt gaaacggtgc ctactgttct
     8221 ggtacggata ccgtccacca gcacgggcgt cccggtcggc gcatggcgtg gatagccatc
     8281 ggcataaccc gccgcgacga tgccaatgcg ttgttcctga gtcacagaat accctccgcc
     8341 atagcctact ctttcacccg cgctcagcgt ctgcacgcca ataatttcgc tactcagcgt
     8401 catcacgggt tttagtccgg tatcggcaat atcccgccac tgtcctgacg gcgacgcgcc
     8461 gtacaaaata atgcccggcc tgacccagtc ataatgcgcc tggggatgcc acagcgtcgc
     8521 tgccgaattt gataacgagt atgcacactg caggccttct gtcgccagcg caatacgtct
     8581 catcgcctcc ccgatacctt ccggatgatc ggcctgagca aaatgtgaca tcagggtcat
     8641 ttcaccgaca ttgcgcattg cccgcaattg ctgccagacg gtctgcgccc gctcaggctg
     8701 aaaaccgagt cggttcatac cgctgttgac tttgacatag atatccagcg gcgcgttaag
     8761 ccgcgcattt tgcagcgctt tcaactgcca gttactgtgg atgcaggtgg tcagccgata
     8821 agtgtcatac gcctccaggt cttgcgcatg gaaaaacccc tccagcatca atatcggccc
     8881 tttccacccg cgctcacgca gggtaatcgc ctcttcaagg ttgagcatag cgaaaccatc
     8941 tgtggcgccc agcgcgctcc agacgcgttc aataccgtgg ccgtaggcgt tggctttcac
     9001 taccgaccag acgcgcgcct ccggggccgc ccggcgcaca atagccaaat tttgtttcat
     9061 tacctgtaaa tcaaggctgg cctgtatagg gcgggtcatt tcacttcctt tatcagttat
     9121 gcgcgctatg caaacgttgc gggcgggtgg gcgtaaaatc ggaacggtat cgcgccacgc
     9181 tcagatcgtc gtagggtatc gctggcgtac gacccaacaa gatatcgctt aacaactggc
     9241 ctgaaccgca ggccatcgtc cagcctaagg tgccgtgtcc agtattaagc cacagatttt
     9301 tataacgggt gcgtcctact accggcgtgc cgtccggcgt catggggcgc aggccggtcc
     9361 agaatgtggc ctgctcaata tgaccgccgc gcggaaaaag atcgcgcaca accatctcca
     9421 gcgtctcgcg gcgcggttgc agtaagtcgg tattaaagcc cacgatttcc gccattcccc
     9481 ccacgcgaat acgcttatca aaacgcgtaa tagcgatttt gtaggtttca tcaagaatcg
     9541 tcgataccgg cgcgccgtct ggctcgacga ttgggatggt taatgaatag cctttcagcg
     9601 gatacaccgg gatatcaaca atgcctttaa gcatcgccgt cgaatacgat ccaaacgcca
     9661 tgacatacgc atctgcttta atgatctcat cggcgcattt cacgccgtaa atctgatcat
     9721 tttcgtacag taatttttcc acgggagtat taaagcgaaa ggttacgccc gcctgctccg
     9781 ccatgcgcgc cagacgctgg gtaaagagct gacagtcccc ggtttcatca ttcggtaagc
     9841 gcagcccgcc ggttaattta tgcgcaacct cagccagagc gggttcaact tccgccagtc
     9901 ggctggcttc caggagctga tacggcaccc cggcatcttc cagcacggcg atatcacggg
     9961 tggcgttctc atactgttgc gcggtgcgga agagttgtag cgttcccccc tggcggcctt
    10021 catattcgat accggtcgcg gcgcgtagcg ttttcaggca gtcgcgacta tattccgcca
    10081 gacgcaccat gcggccttta ttttccatat aatgccgggt atcgcagtta cgcagcattt
    10141 gccacatcca cttcagttga aatggggtgc catccagacg caccgccagc ggcgcatggc
    10201 gctggaacat ccattttatc gccttcagcg gtacgccagg ggccgcccag ggtgccgcat
    10261 atcccggtga aatttgtccg gcattcgccg cgctggtttc ttgcgccggg ccggattcgc
    10321 gatcgatgac ggtgacatca tgccccgcct gactcaagta ccaggcgctg gtcacgccaa
    10381 ctacgccact ccccaggatg acaactcgca tagccactcc gttaatagta aaagaacaat
    10441 cttctgatta catcttgata actcagatga aaatattatt caacatatga cttttttatg
    10501 gtgacgtgct tcacatatac cctaaagaca agcgatccca ttggtttggg atctcctgct
    10561 acgcggcatg gctatacagc ataaaatgat gccaataccc gattttttgc cgttcaatgt
    10621 ggaggaaatc gcaaagaaaa gttttcacga tcaagtcgtt ttttaacatg gtgttctatg
    10681 cttgaaagga ggcgctccat acagagagcg tcgccaacaa tgagggtgcg cgaatggcaa
    10741 tgattgattc catgaacaag gacaccacac gtttgagcga tggccccgac tggacatttg
    10801 atctgctgga tgtttatctg gcagagatag accgcgtggc gaaactctac caactggata
    10861 cttacccgca ccaaattgaa gtcatcactt ccgaacagat gatggacgcc tactccagcg
    10921 tcgggatgcc gatcaactat ccgcactggt cgtttggcaa aaagttcatt gagacggaac
    10981 gtctgtataa gcatggtcaa caaggactgg cttatgaaat tgtgatcaac tctaatccct
    11041 gcattgccta cctgatggaa gagaacacca tcaccatgca ggcgctggtc atggcgcacg
    11101 cctgttacgg ccacaactcc ttttttaaaa ataattatct cttccggagc tggacggatg
    11161 ccagctctat cgtcgattac ctgattttcg cccggaatta cattacccgc tgtgaagaac
    11221 gctacggagt ggatgaagta gaaaaactgc tcgactcctg ccacgcgctg atgaattacg
    11281 gcgtcgatcg ctataagcgc ccgcagaaaa tctcgttgca ggaagagaaa gcgcgacaaa
    11341 aaagccggga agagtatcta caaagccagg tgaatatgct gtggcgcacg ctgccaaaac
    11401 gcgaggaaga aaaaactgtc gccgaagcac gccgctttcc tgctgaaccg caggaaaacc
    11461 tactctattt tatggagaaa aacgccccgt tgctcgagcc gtggcagcgc gaaattctgc
    11521 gcatcgtgcg taaagtcagc cagtattttt atccgcagaa acagacgcag gtcatgaacg
    11581 agggctgggc gaccttctgg cactacacca tcctgaacca tctgtatgat gaaggcaaag
    11641 tgacggaacg ctttatgctg gagtttttac acagccatac caatgtcgta tttcagccgc
    11701 cctataatag cccctggtat agcggaatta acccctatgc gctcggcttt gccatgttcc
    11761 aggatatcaa acgtatttgt cagtcgccca cggatgaaga taaatactgg tttccggata
    11821 ttgccggttc cgactggctg gaaacgctgc acttcgccat gcgcgatttt aaagatgaaa
    11881 gctttatcag tcagttcctg tcgccaaaag tgatgcgtga tttccgtttc ttcacggtac
    11941 ttgatgatga caggcataat tatctggaga tctccgccat tcataacgaa gaaggttatc
    12001 gggagattcg atcaaaactg tcgtcacagt ataacctgag caacctggag ccgaatattc
    12061 aggtctggaa tgtggattta cgcggcgaca gatcgctgac gttgcgttat atcccgcata
    12121 accgcgcgcc gctggataaa ggccgcaaag aggtgctgaa acatgtgcat cggttatggg
    12181 gctttgatgt gatgctggag caacaaaatg aggatggcag cgtagaactg ctggagcgtt
    12241 gtccgccgcg catgaacacg ctgtaatcga gatgctgccc ggtagtgttt gcgtctaccg
    12301 ggcatcgcgg gattatcgtc cctgaatcgc taaatcgccg ggcagatttt tctgcatccg
    12361 atgccaaatc tcgccgctgt catgcccata acgccgcacc gtttcataca cctggtcgtg
    12421 cgcgccctgc tcgcataacg acgataattt atgatagaaa cccagtgcca gactgcgcgc
    12481 ttccggattg gcgaaatagt ggcgaccaat gcgggtgtat aaccctttca tgccgttcag
    12541 gatcaagccg taaataggat tgccggaggc aaatgccaga ccacgaaaga tgttatagtc
    12601 cagatcggcg aatgcatcgg catggtcggc cacttcgtgg gcagtggcca gcacttcctg
    12661 cgccttatcc gggtgttgac gcaatgcggt acgaataaag atagtagaaa tattggtacg
    12721 caccgacaac aaattgtcga tcagttgcgg aacgctttca tgatcaaggc gggccagcgt
    12781 ttcaaggata ttcagccctg acgtttccca aaaattatta acctttgtcg gtttgccatg
    12841 ctgaatggtc agccagccat ctcgcgccag ccgctgtaac acctcgcgta atgtcgtgcg
    12901 cgtcacgccg atcagttcgg agagttctcg ttctgccggt aagatcgtgc caggaggaaa
    12961 gcagttattc cagatacttt caataatata ctcttccgcg aaacccgcgg ggctctgcgc
    13021 cttaatgacc atagtgagat ttccattaca cagcaaaaca tagttgtact catcatacca
    13081 gacgggcgta acacctgata gcggacgcaa tgaagaaaaa ggggatcaag gcaccatttc
    13141 tgatatcgcc tgccaatatc gttaaggact tgcttgcatt cgtcgcgctc gctactctct
    13201 gtgtttaaac ataaaaacgc tatttcattt ttctaggtaa ggaaaaattt catggagatc
    13261 tcatggggtc gcgccatgtg gcgcaacttt ttaggccagt cgcccgactg gtacaaactg
    13321 gcactacttg tctttttaat tgttaaccca ttcattttct tagctaatcc ctttgttgct
    13381 ggttggctgc tggtggcaga gtttatcttc accctggcga tggcgttaaa gtgttacccc
    13441 ctgctgcccg gcgggttact ggccattgaa gccgttatca tcggcatgac cagcgccgcc
    13501 catgtacgtg aagaggttgc cgccaacctg gaagtcttgc tgctgctgat gtttatggtg
    13561 gcaggcatct actttatgaa gcagttattg ctgtttattt ttacccgtct gttactcagt
    13621 atccgctcga agatggttct gtcgctggcc ttttgcgtcg ccgccgcatt cttgtcggct
    13681 ttccttgacg cgcttaccgt cgttgcggtg gtgatcagcg tcgccgtcgg tttttacggg
    13741 atttaccatc gtgtggcctc atcgcgcggc gaagagaacg atatgctgga cgacagccat
    13801 atcgatccgc attacaaaac ggtgctggag caattccgcg gattcttgcg tagtctgatg
    13861 atgcatgcag gcgtggggac ggcgctgggc ggcgtcatga ccatggtcgg ggagccgcaa
    13921 aacctgatca tcgctaaagc tgctggctgg catttcggcg acttcttttt gcggatgtcg
    13981 cctgtcaccg tcccggtact ggtatgtgga ctgttaacct gtatgctggt cgagaaaatg
    14041 cgctggtttg gctatggcga aacgttgccc gaaaaagtcc gcgacgtctt gcagcaattc
    14101 gacgatcaaa gccgtaagaa gcgcacccgc caggataaaa ttaaactaat agtccaggcg
    14161 gttattggcg tctggctggt taccgccctc gccctccatc tcgcggaggt gggactgatt
    14221 ggtctgtcgg tcattattct ggccaccgcg ttaacgggtg tcaccgatga acacgccatc
    14281 ggcaaagcgt ttaccgagtc gctgccgttt actgcgctgt taaccgtttt cttctctatt
    14341 gtggcggtta ttatcgatca acatcttttc gcgccgatta ttcagttcgt cttgcaagcc
    14401 tctgaacacg cacagctaac gctgttctat ctctttaacg gcctgttgtc ttccatctca
    14461 gataacgtct ttgtcggcac catttatatc aacgaagcga aggcggcaat ggaaaacggc
    14521 gcaatcagct taaaacagtt tgagctgcta gctgtggcca tcaataccgg tactaacctg
    14581 ccatcggtag cgacgccaaa tggtcaggcg gcattcttat tcctgctgac ctccgcgctg
    14641 gcgccgttaa tccgtctctc ctatggccgt atggtctgga tggcgttacc gtacactatc
    14701 gtactgaccc tgatagggct actgtgcgtc gaattcactc ttgcgccggc caccgaatgg
    14761 atgactcagg caggatggtt agcaacgctt tcgtaacgtt tggccgggca atacaccgcc
    14821 cggctccgat ttttgcctga taattatcca attacacatt atttcatttc ccgctagtgg
    14881 cgcacgaatt gaattggttt acactgcggt ctctacgcat gttgcaggga aattattatg
    14941 ttgcgatttt taaaccagtg ctcacggggt cggggcgcat ggttactgat ggcgtttacc
    15001 gccctggcgc tggaaatggt ggcgctgtgg ttccagcacg tcatgttact taaaccttgc
    15061 gtgctatgta tttacgaacg ttgcgccctg tttggcgtga tgggcgcggg tctggtcggc
    15121 gcaatagcgc cgaaaacgcc gctgcgatac gtggcaatgg ttatctggat ttacagcgcc
    15181 tggcggggtc tacaactggc gtatgaacat acgatgattc agttgcatcc ctcgccgttc
    15241 atgacctgtg actttatggc gcgctttcca gactggttac cgttgggtaa atggctaccg
    15301 caggtgtttg tggcatccgg tgattgcgcc gagcgccagt ggtcgttttt aacgctggag
    15361 atgccgcaat ggctgttggg gatctttgcc gcttaccttg tggtagcgat agctgtcgtc
    15421 atagctcagg catttaagcc taaaaaacgc gacctgttcg gtcgttgata cacacgctcc
    15481 ttcgggagcg tttttttgcc cgaagcgttg tttgccagtg attaaaaggt gtatattaaa
    15541 tacatctttt aatcaccaca tcagggagat gtcttatgtc ccacttacgc atcccggcaa
    15601 actggaaagt taaacgctct accccctttt acaccaaaga gaatgttccg gcggcactgc
    15661 tctctcatca caacacagcg gcaggcgttt tcggacaact ctgcgtgatg gaaggcaccg
    15721 tgacctacta tggctttgcg aatgaaaccg cgacagaacc agaagtgaaa gtggtgatta
    15781 atgccgggca attcgccacc agtccgccgc aatactggca tcgggtagag ctgagcgatg
    15841 atgcgcggtt caacattcat ttttgggtag aggaagacca tcagggcgag gaaatgtatc
    15901 aacagaaaaa agcctgacat cggtaaacca gttaccactg ggcggcgtcc cgcccagtag
    15961 ccaggtgatt aatggcgcta attaaacgct agagtagttt aattttaacg tggtatccct
    16021 caagcccttt catcgtttct cgcggcgcga actctatttc ggaaacctct tgcccggttt
    16081 tcttccgtag ttcggcgacc tttttgctaa tgagtgccgc gatttcctct tctgctttat
    16141 gtgtcaactc ttcgctgttc attgatttcc tcctttgaac tcgcaaacgg ctaagcgcaa
    16201 taagacagtg tcgtcatgga cgcgctacta ttttaacgta caaaaaatta taggctatct
    16261 ttctgaggat tatcaggatg tttcgcttta gaagatgcaa aaaaccgcct ggcacagacg
    16321 gtgcatcagg cggttggtta atagcacaag acgctatcta cgaggatctt caacctcatt
    16381 ctgggtatcc gggtcgagag gatcgtctcc ctctggcgta tccggaatat tttcaccagg
    16441 aagcggctca tcctctggta atggatcgac taaatcagga cgttcagaca taaagcctcc
    16501 aacgaaccat agttattaaa gataccctac agcactactt ttggtttttc tttggatttt
    16561 ttccttcgtc ttcgggtgtc ttatcaggct tcctgggctg atcctttgaa acgcgcaacg
    16621 gttggttatt catggggtaa ctcctcagga taggcagcga tatactgctt tgaaagtata
    16681 gagtcgccgc catacgtgcg cgagcgcagc gacaaggcgc gtcagggaag aatagaaggc
    16741 agtgataacg ccaggtgacg gaatttgcac gcaattcctg atttcagggg ccgcccagcg
    16801 taaattaaag aattgtaaac aatcagccgt tttgccgaag acttattctg cccacgacgg
    16861 tttatttaaa atatgatcct gccagtcccg tacttcggat tctttaaccg cgatatgacg
    16921 gacagaaatt cgctcgccat gcatagcggc tttcgatcca gtctgcagcg gatgccacgt
    16981 cggcaagggc ttaccttccg ccaacaaacg gtaggcgcag gtcatcggca accattcaaa
    17041 gtctggcaag ttttcgcgag tgagtttgat acagtcgggt tcaaattcaa aacggcgttc
    17101 ataatgacgg cactggcacg ttttgatatt taattgcctg cacgccacgt tggtgaagta
    17161 gatttcatct gtatcttcat ccatcagctt atgcaggcag cattgaccgc agccatcgca
    17221 cagcgactcc cactcggcat cggtcatttc atccagggtt ttacgttgcc agaaaggtgt
    17281 atcgctcatt aaagtatccg ccattgcatt aaagctgcac cttataacca gtctggcctg
    17341 cagatgcaag ttttaccgcc gctgaaggcg gcaagcagat tttacagaac gcgagtagac
    17401 aacgtttcgc cattaaaacg aatgtccagc tcatcgccgc ttaataatgg ccccacgcct
    17461 gccggcgtgc cggttagcac cacgtccccg gctttgagcg taaaatagcg gctcatatag
    17521 gcgataaggg gcacaatagg atgaatcata tccgcggtcg acccttgctg gcgaacctcg
    17581 ccattaacgt taagtccgat aaccgtattt tgcggatcgc cgcagaaggc cgcgacaggg
    17641 atgaagcctg aaatcggaca tgcgttatcg aaacctttgg ctttttccca aggctgtccg
    17701 gcctttttca ttttcccttg aatatcgcgc agggttaaat caagcgccac gccataaccg
    17761 gctatcgctt tacgtacatg atcttcggtc gcctggcgga gcgttgcgcc aatcagcacg
    17821 gcaagctcaa cttcatgatg aacagcgccc atatccgccg gaatcgccag cggctggcga
    17881 atatcacaca atgcggtttc cggcttgata aaaagcacgg gttcttccgg cgtcgcgctg
    17941 cccatctcct tgatgtgatt tgcgtaatta ctgcccacgc agaccacctt acttaccggg
    18001 taatcaagca aggcaccttg ccagttacga tgttgataca tattttcccc taagatcatg
    18061 atggaattca ggcgcggcgc cgaataccgt ttaacggtca gcgtgcgacg tattttgtcc
    18121 caccgaagaa agatgttgtt tcagcaaatc ttccggcggc ggcggcaatt gtaaataata
    18181 gccctgctcg cttaacgcct gttttacttt ttcgagctcg gcattgacta attttttacg
    18241 tccatcaagc ggcagcatca tcgctaactg cggctgaccg aatcctttca tcaacgcgtc
    18301 aggcacccgc gaaaaatcgt cttttttttc gacatacaaa taggtttgat cgcgcttgct
    18361 acttctatag atcacacaaa acatactttt actctgaatt aacgggatgg tgacttgcct
    18421 caatataata ctgactataa catgccttct ggacttcgga atatcactcc gtatcggaga
    18481 tgataaatag caaattgagt aaggccagga tgtcaaacac gccaatcgag cttaaaggca
    18541 gtagcttcac cttatcagtg gttcatttgc atgaagcgga accagaggtt attcgtcagg
    18601 cgttagaaga caaaatagcg caggctcctg cgtttttaaa acacgcccct gtcgttatta
    18661 acgttagcgg tcttgaaagc ccggtaaact ggccggaact gcataagatc gtgacctcaa
    18721 ccggcttacg cattatcggc gtgagcggct gtaaagacgc cagcctgaaa gtagaaatcg
    18781 atcggatggg tcttccttta ctgactgaag gtaaagagaa agcggttcgg cctgcgcccg
    18841 ttgagccggc aacgcccagc gaaccgccgc aaaacgctaa tcccatcaca aaaacgcgat
    18901 taattgatgt tccggttcgt tccggtcagc gcatttatgc tccacaatgt gatctgattg
    18961 ttacaagtca cgtcagcgct ggcgcagagc ttatcgctga cggcaatatc catgtctatg
    19021 gcatgatgag aggtcgcgcg ctggcagggg cgagcggcga tcgggaagcg caaatttttt
    19081 gtacccatct gacggcagaa ctggtctcta tcgcaggtgt ttactggctg agtgataaaa
    19141 tcccggcaga attttatggc aaagcggcgc gcctgcgttt agcagacaac gctttgacag
    19201 ttcaaccgtt gaattgatcc ctttttaaca aggaattttt atggcacgca ttattgttgt
    19261 tacttcgggt aaagggggcg ttggcaagac cacctccagc gcggccatcg ctacaggttt
    19321 ggcccagaag ggaaagaaaa ctgtcgtcat tgattttgat atcggactgc gtaacctcga
    19381 tctgattatg gggtgcgaac gtcgtgtcgt ttacgatttt gtaaacgtca ttcagggcga
    19441 tgcgacactg aatcaggcgc tgatcaaaga taagcgtact gaaaatctct tcattcttcc
    19501 ggcgtcgcag acccgggata aagacgcgct aacgcgcgaa ggcgtcgcta aggtactgga
    19561 ctcactgaaa gcaatggact ttgagttcat tgtttgcgac tcgccggcgg gtatcgaaac
    19621 cggggcgctg atggcgctct attttgccga tgaagcgatc atcacgacca acccggaagt
    19681 ctcttctgtc cgtgactcgg accgtattct gggtattctg gcatcgaaat ctcgtcgcgc
    19741 agaaaatggc gaagaaccga ttaaagaata tctcctgttg acgcgctaca atccaggccg
    19801 cgtcaataaa ggcgacatgc tcagcatgga agatgtactg gagattctgc gtattaaact
    19861 cgtcggtgtg atcccggaag atcaatccgt actgcgcgca tcgaaccagg gcgaaccggt
    19921 gattcttgac gccactgcgg atgcgggtaa agcctatgca gataccgtag atcgtctgtt
    19981 gggagaagaa cgtcctttcc gcttcattga agaagagaag aaaggtttcc tcaaacgcct
    20041 gttcggagga taaattatgg cattactgga tttttttctc tcgcggaaaa agagtaccgc
    20101 taatattgca aaagagcggt tgcaaatcat tgtcgcggaa cgtcgccgta gcgatgccga
    20161 accgcattat ttaccgcagt tacgtaaaga tattcttgag gtcatttgta aatacgtaca
    20221 aatcgatccg gaaatggtta ccgtccagct tgagcaaaaa gatggtgata tctccatcct
    20281 tgaacttaac gtaacgctgc cggaagccga agagtcaaaa taagctcttt tatgggaaaa
    20341 ttcctggatt aaaaaaggca gaagaatctg ccttttttat ttttttacat tattccgaat
    20401 acggacattt atttcactgg ccgttttccc ggcaattacc gtcgttaaag cgaatactcc
    20461 tgcaacagaa gagttaactt ctccgccatc agttcggcgc gccagccgga aatcaattcc
    20521 ggttgcccat tttgcggttt taatttccag tgccagttaa gcaactgatt aatctgccga
    20581 cgcgatgcca gtagctcgcc gctgacgtga tgcgacgcgc tcacctccgc cactagcgct
    20641 ttgatggcct taaacgcttt gcgatagccc ggcatgtcca tcagattcaa caggggttcc
    20701 ggcaatgcct cttccggtag cgcctgtgct ttcgccacca gcgatatcaa cgtcttgccg
    20761 tgaaaacgaa tctcgctgcc ggaaagcccc aggctatcca gctcaccgag actgcccggc
    20821 atataacgcg cgaccgccca caggttttct tcacgcacaa caaagttcac cgccatatcg
    20881 cgctcacgcg ccttacgtag ccgccagtca gctaaaagtt gcagacaggc taactggcga
    20941 gtacgcagtt gccaggcatt ggtgatatcc cgccatgctt cttccggcgc ctgaatctcc
    21001 tgacgacgct gctgcatcaa tcggcattca tcaagcgcgg caggcagcca tcctgcggct
    21061 tcagtttcaa tcatcagctt tttggcgatc ggtaacagat accagacatc cgccgccgcg
    21121 tattcacact gacgttcgct taaaggccgg gctaaccagt cggtacgaga ctcgcttttg
    21181 tccagcgcca cgcccgtata ctcttctacc atcgacgcaa aaccccacga cagcggacgc
    21241 ccgcaaaacg ccgccagaat ttgcgtatca atcagaggtt ccggcagttc gccaaacgca
    21301 ttcagaaata cttccagatc ttcgctaccc gcgtgcagaa atttggtgat tcccgtatcg
    21361 cgcaacaccg cttttaacgg cgaccagtcg ctgatgccga gcggatcgat cagggcgaca
    21421 tttgccccgt caaataactg gatcaatcct aactgcgggt aataggtgcg ggtacggaca
    21481 aattccgtat ctaaagcaat agccggacat gcgcggacag cctcacacag gctcgccagc
    21541 gcatcgtccg tttcaatcat ttggtaattc aaatcgtgtt ctctttggtt cgcgccaaaa
    21601 aaaacgccgg cttaaccggc gtctctcgtt agctgactta acgctcaggc tttattgtct
    21661 actttgccac gggcttcgtc acgcagttct cgtcgtaaaa ttttcccaac gttagatttt
    21721 ggtaattcct cgcgaaactc gacctgtttg ggcaccttat atccggtcag atggcgacgg
    21781 cagaaggtga tcaacgcatc gtcagtcaat gccggatctt tcttaaccac aaaaagcttc
    21841 accgcttcgc cgctactacc ggaaggcacg ccaaccgccg cgacttcctg cacgccagaa
    21901 tgctgcatca ccacatcttc aatttcgttt ggataaacgt tgaaaccaga aaccagaatc
    21961 atatctttct tacgatcgac aatccgcaga aagccgtctt catccataac cgcaatatcg
    22021 cccgtatgca gccagccatc tttaatgatt tcatccgtcg cgtcaggacg ctgccagtat
    22081 cccagcataa cctgcgggcc tttcacgcaa agctctccgg cctcacccgg cgcgacttcg
    22141 ttgtcatcgt catccaccag tttggcttct gttgacggta ctggcaggcc gatactgccg
    22201 ctgtgataat caatatcatg cgggttgacg ctcaccagcg gggcgcactc ggtcagcccg
    22261 tagccttcca gcaggtattg cccggtcagc tttacccaac gttccgcaac gacgttttgc
    22321 accggcatcc cgccgccggc tgacagatgc agcgaagaaa aatccagctg ttgaaactct
    22381 ttattattga gcagggcgtt gaatagcgta ttaacgccag tcatcgccgt aaatggatat
    22441 ttcgccagct ccttgaccag accggggata tcacgcggat tggtaatcag caggttttgc
    22501 ccacccagct cgataaaaag cagacagttc atggttaagg caaaaatgtg atacagcggc
    22561 agcgcggtca ctaccagctc tttccccggg tgcagcagcg gcccataggt cgctttcacc
    22621 tgctccagat tcgccagcat attgcggtgg gtcaacatcg cgcctttcgc cacgcccgtc
    22681 gtaccgccag tatattgcag gaaagccaga tcttcagcga caacctcggg tttgacatac
    22741 tgcatacggt agccatgctg tagcgcgctg cgaaacgaga tcgcatctgg caagtggtat
    22801 tttggcacca gacgcttgat gtatttcacg acaaagttaa caaccgtacc tttggcggta
    22861 gaaagctggt cgcccatccg cgtcagaata acgtgctgta ccgacgtttt ctcgaccact
    22921 ttttccagcg tatgggcaaa gttagaaaca ataatgattg ccgccgcgcc gctatcgtta
    22981 agctgatgct caagttcgcg cggcgtgtaa agcgggttaa cgttcaccac aatcatgccg
    23041 gcgcgtaaaa taccaaatag cgcgacagga tactgcaaca ggtttggcat catcagcgcc
    23101 acacggtcgc cttttttgag tcccagccct tgttgtaaat aagccgcaaa tgcccgacta
    23161 cgttcttcta atttacggaa ggtcattacc tcccccatat tgacgaacgc aggctgatcg
    23221 gcatagcgcg tcgccgcatg ttcaaacagt tcaaccaggg attgataacg gtcagggttg
    23281 atctccgccg gaacatcagc aggataacgg ttaagccaaa ccttcttcaa tgcatcacct
    23341 ctaaaatgag tgttcgtcgt catcacaacc ccagtcaata aacaagtcgt taacattata
    23401 ttaactcagc gtaccagttt attaattacg caactgaaag gttgcgaagc gcgtcac
//
LOCUS       DAJVBX010000054        23348 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.054, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000054 DAJVBX010000000
VERSION     DAJVBX010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 23348)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23348
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.054"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..1573
                     /locus_tag="OPV72_001837"
     CDS             <1..1573
                     /locus_tag="OPV72_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCR9914157.1"
                     /translation="NRIFLLILFTSTIVMLAITWYLTDITKERLHYQVGQRALIQAMQ
                     ISAMPELVEAVEAHDLSRIKALIDPMRSFSDATYITVGNEKGQRLYHVNPDEIGKYME
                     GGDSDDALYNAKSYVSVRKGSLGSSLRGKSPIQDSTGKVIGIVSVGYTLEQLESWLNL
                     QISSLLFPMAILLLVLLYCARRFSLHIKKQMLNMEPQQLSQLLIQQSVLFESVFEGLI
                     AIDSHHRITAINQTARRLLNLSQPESELIGYAIHHIVLPEAFFYDAPQKNKKDEIVTF
                     NQMKVIASRMAVIIDNQPQGWVISFRNKDDINTLNLQLSQVRQYADNLRAVQHEHRNL
                     ISTIAGLLFLKRYDNALALIQQQSESHQKVLDFISHNFRDHHLAGLLIGKYYRAKELG
                     LELIFDPSSFVEHLPSSLSHNEWISIVGNLLDNAYNATLLNREGSRQIECLINSEGNE
                     VIIEVADQGCGIDENIRQHIFERGVTTHNNGDHGIGLWLVHSYVKQANGDIIVDNNNS
                     FGTIFTLYIPFTREE"
     gene            1575..2261
                     /locus_tag="OPV72_001838"
     CDS             1575..2261
                     /locus_tag="OPV72_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HCR9914158.1"
                     /translation="MDSITTLIVEDEPMLAEILVDTIKLFPQFSIVGIADKLESAKKQ
                     IRLYQPQLILLDNFLPDGKGIDLIRHTISTNYTGRIIFITADNHMDTISDALRMGVFD
                     YLIKPVHYQRLQHTLERFTRYRSSLRSSEQANQTHVDALFNIQAKEQTAEPNSGLRGI
                     DENTFNRVRQIFADPQAVHTADTLAQILGSSKTTARRYLEQGVKNNFLEAEISYGKVG
                     RPERLYRGKV"
     gene            complement(2283..3203)
                     /gene="rihC"
                     /locus_tag="OPV72_001839"
     CDS             complement(2283..3203)
                     /gene="rihC"
                     /locus_tag="OPV72_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleoside hydrolase RihC"
                     /protein_id="HCR9914159.1"
                     /translation="MTASLHIILDTDPGIDDAAAIAAALFAPQLDLQLITTVAGNVSV
                     EKTTRNALQLLHFWNSDIPLAQGAATPLLRPLRDAAYVHGESGMEGYDFVDHQRQPLA
                     KPAFIAIRDVLMNAPEPMTLVAIGPLTNIALLLMHYPECACNIRRLVLMGGSAGRGNF
                     TPNAEFNIAVDPEAAALVFRSGLEIVMCGLDVTNQAMLSPDFLNKLPALNRTGKMLHS
                     LFNHYRSGSMRTGVRMHDLCAIAWLVRPELFTLQSCFVAVETQGEYTAGTTVVDIEGR
                     LGQPANAQVALALDVDGFRQWVAEVFAYVP"
     gene            complement(3219..4421)
                     /locus_tag="OPV72_001840"
     CDS             complement(3219..4421)
                     /locus_tag="OPV72_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite reductase"
                     /protein_id="HCR9914160.1"
                     /translation="MGKIKYRLPTLLAIGFWMDAASATVLELPAWERNYTGTIAGKPV
                     NVNITRFGNTLYGHYCYEPCNQHKAVIVLRGSLQDKEVHLEERVKALSGYWNAEISSS
                     EIKGEWTSADKKRHFPVALIYYKPKNSPDIVLVTNTNDAGGYDPSKEIDCGNTPAISA
                     IKLYRDGKLIQTLDTASVGTCSPFMPQWGDVNFDGYPDLSIVTELLAGPDAPVQTWLY
                     DPAKQRYVDAPASYQEITSPEIDAEHKQIVSYWRGGCCSHGVNVYRWKGKTIELIDRG
                     ESYFQPVISKGKMYNCYMTPSYADGRIIYPLVRKNGHLTPPLSLDGTCQSFWLTGNVR
                     TVIQAEKPGAEPESLEIQWQENKASPGRFCPLVPFVEGDKLSPRLVTDDDVPDTCISR
                     AEYEDIKQ"
     gene            complement(4621..5571)
                     /gene="ispH"
                     /locus_tag="OPV72_001841"
                     /gene_synonym="lytB"
     CDS             complement(4621..5571)
                     /gene="ispH"
                     /locus_tag="OPV72_001841"
                     /gene_synonym="lytB"
                     /EC_number="1.17.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HCR9914161.1"
                     /translation="MQILLANPRGFCAGVDRAISIVENALAIYGAPIYVRHEVVHNRY
                     VVDSLRQRGAIFIEQISEVPDGAILIFSAHGVSQAVRNEAKSRDLTVFDATCPLVTKV
                     HMEVARASRRGEESILIGHAGHPEVEGTMGQYSNPEGGMYLVESPEDVWTLNVKNEGK
                     LSFMTQTTLSVDDTSDVIDALRKRFPKIVGPRKDDICYATTNRQEAVRALAEQADVVL
                     VVGSKNSSNSNRLAELAQRMGRTAFLIDDAADIQEAWVKDAACVGVTAGASAPDILVQ
                     NVIARLREFGGGEAVTLEGREENIVFEVPKELRVDVREVE"
     gene            complement(5574..6023)
                     /gene="fkpB"
                     /locus_tag="OPV72_001842"
     CDS             complement(5574..6023)
                     /gene="fkpB"
                     /locus_tag="OPV72_001842"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HCR9914162.1"
                     /translation="MSKSVQSNSAILVHFTLKLDDGSTAESTRNNGKPALFRLGDTSL
                     SEGLEQQLLGLKEGEKKAFSLEPDAAFGVPSPDLIQYFSRREFMAAGEPEVGAIMLFT
                     AMDGSEMPGVIREINGDSITVDFNHPLAGHTVHFDIEVLEIDPALEA"
     gene            complement(6178..6678)
                     /gene="lspA"
                     /locus_tag="OPV72_001843"
     CDS             complement(6178..6678)
                     /gene="lspA"
                     /locus_tag="OPV72_001843"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HCR9914163.1"
                     /translation="MSKPLCSTGLRWLWLVVVVLIIDLGSKYLILQNFALGDTVGLFP
                     SLNLHYARNYGAAFSFLADSGSWQRWFFAGIAIGICVILLVMMYRSKATQKLNNIAYA
                     LIIGGALGNLFDRLWHGFVVDMIDFYVGDWHFATFNLADTAICIGAALIVLEGFLPKP
                     TAKEQA"
     gene            complement(6678..9512)
                     /gene="ileS"
                     /locus_tag="OPV72_001844"
     CDS             complement(6678..9512)
                     /gene="ileS"
                     /locus_tag="OPV72_001844"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HCR9914164.1"
                     /translation="MSDYKSTLNLPETGFPMRGDLAKREPGMLARWTDDDLYGIIRAA
                     KKGKKTFILHDGPPYANGSIHIGHSVNKILKDIIVKSKGLSGFDSPYVPGWDCHGLPI
                     ELKVEQEFGKPGEKFTAAEFRAKCREYAATQVDGQRKDFIRLGVLGDWSHPYLTMDFK
                     TEANIIRALGRIIKNGHLHKGAKPVHWCVDCRSALAEAEVEYYDKTSPSIDVAFRAVD
                     QDAVKAKFGLPGVSGPVSLVIWTTTPWTLPANRAISLAPDFDYALVQIDGQAVILAKD
                     LVESVIQRIGAAEYTILGTVKGAELELLRFTHPFMGFDVPAILGDHVTLDAGTGAVHT
                     APGHGPDDYVIGQKYGLETANPVGPDGAYLPGTYPTLDGVNVFKANDIVIELLKEKGA
                     LLHVEKMQHSYPCCWRHKTPIIFRATPQWFVSMDKEGLRQQSLKEIKGVQWIPDWGQA
                     RIESMVANRPDWCISRQRTWGVPMSLFVHKETQELLPIERTLAAMEEVAKRVEVDGIQ
                     AWWDLDPKEILGEDADQYEKVPDTLDVWFDSGSTSYSVVDARPEFAGHAADMYLEGSD
                     QHRGWFMSSLMISVAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMNKLGA
                     DILRLWVASTDYTGEMAVSDEILKRAADSYRRIRNTARFLLANLNGFNPATDMVKPEE
                     MVVLDRWAVGCAKTAQQEILKAYEAYDFHEVVQRLMRFCSVEMGSFYLDIIKDRQYTA
                     KADSVARRSCQTALYHIAEALVRWMAPIMSFTADEIWGYLPGEREKYVFTGEWYDGLF
                     GLEENEEFNDAFWDDVRYIKDQVNKELENQKANGIKSNLEAKVTLKYADDANGTIKKL
                     KLLGEEVRFIFITSQFVISEQAGGIDDENIQYNAGNTTVQAVVTRAEGDKCPRCWHYT
                     TDVGKVAEHADICGRCVSNIAGNGEQRKFA"
     gene            complement(9557..10495)
                     /gene="ribF"
                     /locus_tag="OPV72_001845"
     CDS             complement(9557..10495)
                     /gene="ribF"
                     /locus_tag="OPV72_001845"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HCR9914165.1"
                     /translation="MKLIRGIHNLSQAPHGCVLTIGNFDGVHRGHRALLQGLQEEGRR
                     RGLPVVVMIFEPQPLELFATDKAPARLTRLREKLHYLAQCGVDYVLCVKFDRRFAALT
                     AQTFISELLVERLGVQFLAVGDDFRFGASRAGDFLLLQKAGAEYGFAVSSTQTFCEGG
                     VRISSTAVRQALAEDNLALAESLLGHPFTISGRVVHGDELGRTIGFPTANLPLRRQVS
                     PVKGVYAVEVTGLGDKPLPGVANIGTRPTVAGVRQQLEVHLLDVVMDLYGRHIDVILR
                     KKIRNEQRFASLDELKAQIARDELTARKFFGLAGQV"
     gene            complement(10503..10718)
                     /locus_tag="OPV72_001846"
     CDS             complement(10503..10718)
                     /locus_tag="OPV72_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2575 domain-containing protein"
                     /protein_id="HCR9914166.1"
                     /translation="MQHSLRSDGAGFYQLACCEYSLSMRKIALSGGFWGGVCRMAMKS
                     IFFMFHQGNRRLTLTAVQGILLRFSLF"
     gene            10824..11087
                     /gene="rpsT"
                     /locus_tag="OPV72_001847"
     CDS             10824..11087
                     /gene="rpsT"
                     /locus_tag="OPV72_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006117633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HCR9914167.1"
                     /translation="MANIKSAKKRAVQSEKARKHNASRRSMMRTFIKKVYAAIEAGDK
                     AAALKAFNEMQPIVDRQAAKGLIHKNKAARHKANLTAQINKLA"
     gene            11141..11386
                     /locus_tag="OPV72_001848"
     CDS             11141..11386
                     /locus_tag="OPV72_001848"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914168.1"
                     /translation="MPAICRFSRQPLALTSLVHALPVPAYFFSYPSLSHVILESYFLS
                     LFSFSYFITEKTVTTLANKNIAHLKTNKRNPDVRFNN"
     gene            11544..12917
                     /locus_tag="OPV72_001849"
     CDS             11544..12917
                     /locus_tag="OPV72_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR9914169.1"
                     /translation="MSSVIEDTQPSGSASLSLLQRISYGSLDVAGNLLYCFGSTYILY
                     FYTDVAGISLAVAGIILLLARIVDGIDAPIWGIIIDKTRSRYGKCRPWFLWLPLPFAV
                     FSALSFWSPDISITGKAIYAAISYMIASILFTGLNTPLSAILPLMTLSPKERLVLNSW
                     RMTGGQIGVLLMNATALPLVAFLGNGDDHAGFIYTAITFAIISCALTLFAFKNIREMD
                     ADKIQHEPKLPMKKSFAAMKGNWPWILMVLANLIFWIALQQRSTTIVYYLTYNLDRKD
                     LVPLINSLATIQILFIIAIPFFSKYLAKTWIWVGGLLVATFGGVMMWLAADNITFLIA
                     AWILGNIGSGIACSMPFAMLGFAVDFGAWKTGIKATGILIAFGSTFCIKMGSGLGTAL
                     AAWIMNSFGYVPNHAQSAAGLEGITWAFIWAPALLFALAAIPLLFFRKYEAMEEKIRH
                     DLETINS"
     gene            12957..14996
                     /locus_tag="OPV72_001850"
     CDS             12957..14996
                     /locus_tag="OPV72_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HCR9914170.1"
                     /translation="MPFMQQDPRRLVWQQNDRYLWIEPWGENSLRVRSGRHLPVMRNE
                     DWALTEPVAESQCHIDYEHHQATLTNGKIIAIVNQKGQVTFYRHPHKPLLQEFWRLRG
                     EIGEDESSHGQYVSALNLEGREFRPIQGGKYSLKARFEATEGEKIYGMGQYQQANLDL
                     KGCVLELAQRNSQASVPFMLSSLGYGFLWNNPAVGRVTFAQNVTEWEAQVSEQLDYWI
                     TAGDTPAEIGRAYALATGTPPMMPDYAMGFWQCKLRYRTQEELLEVAREYKRRNLPIS
                     VIVIDFFHWPNQGDWMFDARDWPDPDAMIAELKSLGIELMVSVWPTVDNRTESYREMR
                     ENGWLVQTERGLPINMDFLGNTTYFDATHPGARDYVWGKAKRNYHDKGVKLFWLDEAE
                     PEFSVYDYDNYRYHAGPVLEVGNIYPRMYAKTFFDGMKADGEDQVINLLRCAWAGSQK
                     YGALVWSGDIHSSFRSLRNQFAAGLNMGIAGIPWWTTDIGGFHGGNIHDPKFHELLIR
                     WFQWGVFSPVMRLHGNRDPQILPAQPYRDGIAQCPTGAPNEVWSYGEEVCDVLTGCLA
                     LREKLKPYIKALMEETHKHNTPVMRPLFFEFPEQETSWTITDQYCFGPDLLIAPVMHE
                     GMRERDVWLPEGETWTDLATGESYSGGQTLHYATPLNRIPVFIREGGQYRSLLNL"
     gene            complement(15051..15950)
                     /gene="nhaR"
                     /locus_tag="OPV72_001851"
     CDS             complement(15051..15950)
                     /gene="nhaR"
                     /locus_tag="OPV72_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional activator NhaR"
                     /protein_id="HCR9914171.1"
                     /translation="MSMSHINYNHLYYFWHVYKEGSVVGAAEALFLTPQTITGQIKAL
                     EERLQGKLFKRKGRGLEPSELGELVFRYADKMFTLSQEMLDIVNYRKESNLLFDVGVA
                     DALSKRLVSSVLDAAVVVDEPIHLRCFESTHEMLLEQLSQHKLDMIISDCPIDSTQQE
                     GLFSVKIGECSVSFWCTNPLPEKAFPACLEERRLLVPGRRSMLGRKLLNWFNSQGLQV
                     EILGEFDDAALMKAFGATHDAIFVAPSLYSLDFYADESVIEIGRVENVMEEYHAIFAE
                     RMIQHPAVQRICNADYSALFKLQ"
     gene            complement(16012..17178)
                     /gene="nhaA"
                     /locus_tag="OPV72_001852"
     CDS             complement(16012..17178)
                     /gene="nhaA"
                     /locus_tag="OPV72_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaA"
                     /protein_id="HCR9914172.1"
                     /translation="MKHLHRFFSSDASGGIILIIAAALAMLMANMGATSGWYHDFLET
                     PVQLRVGALEINKNMLLWINDALMAVFFLLIGLEVKRELMQGSLASLRQAAFPVIAAI
                     GGMIVPALLYLAFNYSDPVTREGWAIPAATDIAFALGVLALLGSRVPLALKIFLMALA
                     IIDDLGAIIIIALFYTSDLSIVSLGVAAFAIAVLALLNLCGVRRTGVYILVGAVLWTA
                     VLKSGVHATLAGVIVGFFIPLKEKHGRSPAKRLEHVLHPWVAYLILPLFAFANAGVSL
                     QGVTMDGLTSMLPLGIIAGLLIGKPLGISLFCWLALRFKLAHLPQGTTYQQIMAVGIL
                     CGIGFTMSIFIASLAFGNIDPELINWAKLGILIGSLLSAVVGYSWLRARLNAPA"
     gene            complement(17341..19056)
                     /locus_tag="OPV72_001853"
     CDS             complement(17341..19056)
                     /locus_tag="OPV72_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aryl-sulfate sulfotransferase"
                     /protein_id="HCR9914173.1"
                     /translation="MNTLTATSVVLPAPRPAINQGIDINNEIVLNHTAIYENCLAQVT
                     QENTVENALMLLDPYGTAPLSAYAGVWSLEPAEIMVTVQDAAKTAMPVEHLYTLTAGA
                     NLLPVLGLVAETENRIVFSQADTPLAVYTLTTQPLPPVDSAEVVLGFPIINVTQPATD
                     VDKMAPGFYFVTHFDRYNYALDQNGLVRWYVTQDYPSYNFVRIDNGHFLTTSEAKNTY
                     LDMYEFDMMGRLHTFYNLDNQFHHSIWPWDSNTIVAPSEYTSGRPDDLKTNEDGVSVV
                     DLATGLETAYYDMAKVLDTTRVSRPSGTAPGEDPTVKDWLHINQSYVNETNQLLIASG
                     RHQSAVFGVDLQTQALRFILSTHEDWDDAYQPYLLTPVDSEGVALYDFSKQEDIDAAD
                     RDFWTWGQHNVVEIANNTPGIVEFMVFDNGNYRSRDDSKSLLPPDNYSRIVHFVVNMN
                     EMTVMRPFEYGKELGARGYSSCVSAKAIQQNGNIVVHFADCTFDENGRAISCQPGESD
                     IIDPQAGSEAMGLLILQEIAPTEKTVLFEATMTSGYYKNAETNGEGYRYDITSFRVYK
                     MDLYA"
     gene            complement(19183..20435)
                     /locus_tag="OPV72_001854"
                     /pseudo
     CDS             complement(19183..20435)
                     /locus_tag="OPV72_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459042.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
     gene            complement(20454..21644)
                     /locus_tag="OPV72_001855"
     CDS             complement(20454..21644)
                     /locus_tag="OPV72_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfatase maturase"
                     /protein_id="HCR9914174.1"
                     /translation="MMFGKSCQVMVKPTGSVCNLDCKYCFYLEKEKLYPDRKNHYKMS
                     EETLELFIRQQIAAQDIDEVIFAWQGGEPTLMGIPFYRKAVEFQQRYCGGKTIVNTFQ
                     TNGILINDDWATFFREHDFLVGVSIDGDAALHDEWRVTRSGKPTHEKVENAVRCLAQH
                     DVEFNTLTVVNRTNMHHPVQVYRYLKSVGSRYMQFIPLVERCGENGLAQPQDKHIAMT
                     PWSVDSLQFGQFLNAVFDIWIREDIGDIGIQLFEQTLAAWCGLPPQVCVFAPTCGSAF
                     AMEMNGDVYNCDHFVYPQFKLGNIHQKTLRQMNQGEQNRQFGSDKQRSMAQECHRCQW
                     KFACYGGCPKHRFLPSASGATNHNYLCAGYQAFFSHTATAMSAMRTLYEKGISLAEIK
                     SIFV"
     gene            complement(21743..23236)
                     /locus_tag="OPV72_001856"
     CDS             complement(21743..23236)
                     /locus_tag="OPV72_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HCR9914175.1"
                     /translation="MKRTVVASMIGLALCAGCVLSTAQAATAKRPNLVIILADDLGYG
                     DLATYGHRIVKTPNIDKLAQEGVKFTDYYAPAPLCSPSRAGLLTGRMPFRTGIRSWIP
                     EGKDVALGRNELTIANLLKQQGYDTAMMGKLHLNAGGDRTDQPQAKDMGFDYTLVNPA
                     GFVTDATLDNAKERPRYGVVHPTGWIRNGQHIGRADKMSGEFVSSEVVNWLDNKKDDN
                     PFFLYVAFTEVHSPLASPKKYLDMYSQYMTDYQKQHPDLFYGDWADKPWRGTGEYYAN
                     ISYMDEQVGKVLDKIKAMGEEDNTIVIFTSDNGPVTREARKVYELKLAGETDGLRGRK
                     DNLWEGGIRVPAIIKYGKHIPQGMVTDTPVYGLDWLPTLANMMDFKLPTDRTYDGQSL
                     VPLLKDKTLKRQKPLIFGIDMPFQDDPTDEWAIRDGDWKMIIDRQNKPKYLYNLKTDR
                     FETLNQIGKQPQIEKQLYGKFLKYKKDIDNDSLMKARGDKPTPVTWG"
BASE COUNT         5787 a         6395 c         5607 g         5559 t
ORIGIN      
        1 aaaccggata tttctactga tcctgtttac atccaccatc gtgatgctgg caatcacctg
       61 gtatctgacc gatatcacga aagagcgcct gcattatcag gtgggccaac gtgcgcttat
      121 tcaagcaatg caaatatccg ctatgccaga attagttgaa gccgtagagg cgcatgattt
      181 gtcacgcatc aaagcgctga ttgacccaat gcgctcgttt tcggacgcga cttacattac
      241 cgttggcaac gaaaaaggtc agcgactgta tcacgtcaac ccggatgaga tcggcaaata
      301 tatggagggc ggcgatagcg acgacgcgct gtataatgct aaaagctacg tatcggtgcg
      361 caaaggttca ttaggctctt ccttgcgtgg taaatccccg attcaggaca gtaccggtaa
      421 agtcatcggt attgtttccg tcggctatac tctggaacag ttggagagct ggcttaactt
      481 acaaatcagc tcgttgctgt tcccgatggc gatactgttg ctggtgctgt tgtactgcgc
      541 ccgccgcttc tcgctgcata ttaaaaagca gatgcttaac atggagccgc agcagctttc
      601 acaactatta attcagcaaa gcgtgttatt tgagtcggta tttgaagggt tgatcgccat
      661 tgactcccat caccgtatta ccgccattaa tcaaacggct cgccgcttac tgaatctgag
      721 ccaaccggag tctgaactca ttggctatgc aatccaccat atcgtgttgc cggaggcctt
      781 cttttacgat gcgccgcaaa aaaacaaaaa agatgagatc gtcactttta accaaatgaa
      841 agtcatcgcc agtcgcatgg cggtcattat tgacaaccag cctcagggct gggttattag
      901 ctttcgcaac aaagacgata tcaatacact caacctgcag ttaagtcagg tgcggcaata
      961 cgccgataac ctgcgcgccg tgcagcatga gcatcgcaac cttatttcca ccattgccgg
     1021 actgctgttc ctgaagcgct acgataatgc gctggcgctg attcagcagc agtcggaaag
     1081 ccaccaaaaa gtactcgatt ttatttccca taatttccgc gaccaccacc ttgcggggct
     1141 attaatcggt aaatattatc gggcaaaaga gctggggctg gagctgattt tcgatccttc
     1201 aagctttgtt gaacacctgc cgtcatcgct ctcgcataat gaatggattt cgattgttgg
     1261 caatttattg gacaacgcct ataacgccac cctgctcaat cgcgaaggct cgcgacagat
     1321 tgagtgcctg atcaatagcg aaggtaatga agtcattatt gaagttgccg atcagggatg
     1381 tggtattgac gaaaatatcc gccagcatat tttcgagcgt ggagtgacca cccacaacaa
     1441 cggcgatcac ggaattggat tatggttggt gcacagctac gtcaagcagg ccaatggcga
     1501 cattatcgtc gataacaata attcttttgg caccattttt accctctata tcccttttac
     1561 cagagaagaa taacatggat agcattacga cactcatcgt tgaagacgaa ccgatgctag
     1621 cggaaatcct ggtggacacc atcaagcttt ttcctcagtt ttcaatcgtc ggtatcgcag
     1681 acaagctgga aagtgcgaag aagcaaatac gcctctatca accacagtta attctattgg
     1741 ataatttttt acccgatggc aaagggatcg atttaattcg tcataccatc agcaccaact
     1801 acacggggcg aattattttc attaccgccg acaatcatat ggataccatc agcgatgcct
     1861 tacgcatggg cgtattcgat tatctgatta agccggtaca ttatcagcgc ctgcagcata
     1921 ccctggagcg gttcacccgt taccgcagtt cgttacgttc cagtgagcag gcaaaccaga
     1981 cgcacgttga tgccttattt aatatccagg ccaaagaaca aaccgcagaa ccgaatagcg
     2041 gactgcgggg aattgatgaa aacaccttca accgggtacg acaaatattc gccgacccgc
     2101 aggcagtaca tacagcagac actctggcgc aaattctggg cagcagtaaa accactgccc
     2161 gacgctatct ggaacaaggc gtgaaaaata actttctcga agcggagatc agctacggga
     2221 aagtgggcag gccggagaga ctctatcgcg gcaaagtatg agattatggc gccaacatgt
     2281 aattacggca cataggcaaa cacctcagcc acccactgac gaaaaccgtc cacatccagc
     2341 gccagcgcca cctgcgcgtt ggcgggctgc cccagacgcc cttcaatatc aacgaccgtc
     2401 gtgcctgcgg tatattcccc ctgcgtttct acggccacaa aacaggattg cagggtaaaa
     2461 agctccggac gcaccagcca ggcgatcgca cagagatcgt gcatccggac gccagtgcgc
     2521 atactaccgc tgcgataatg gttgaacagg ctgtgcaaca tcttaccggt gcgattcagc
     2581 gcaggcagtt tattcagaaa atctggcgag agcattgcct gattcgtgac atcaagccca
     2641 cacatcacaa tctccagacc gctgcggaac accagcgccg cggcctccgg atcgacagca
     2701 atgttaaatt cagcattagg cgtaaaattg ccgcgccctg cggaaccgcc catcaacacc
     2761 agacggcgaa tgttacacgc acactccgga tagtgcatca gtagcaacgc aatattggtc
     2821 aatggcccaa tcgccaccaa tgtcatgggc tccggggcgt tcatcaacac atcccggata
     2881 gcgataaacg caggcttcgc caacggttga cgctgatggt cgacaaaatc atagccttcc
     2941 ataccggatt cgccgtggac gtatgccgca tcgcgtaacg gacgcagcag cggcgtcgcg
     3001 gccccctggg caagtgggat atcgctgttc cagaaatgca gaagctgcaa cgcattacgg
     3061 gtcgtttttt caacggaaac attgcctgcg acggtggtta ttagttgcag atcaagctgg
     3121 ggggcgaaca gcgcagcggc aatcgcagcc gcgtcatcaa tgcccggatc ggtatcaaga
     3181 ataatgtgta gggatgctgt cattaacgct ctcctgacct attgttttat atcttcatac
     3241 tcagcgcgac tgatacaggt atcaggcaca tcgtcatccg tcaccagacg cggacttagc
     3301 ttatcacctt cgacaaacgg aactaatggg caaaaacgcc ctggcgatgc tttgttttcc
     3361 tgccactgaa tctcaagcga ttcgggctca gcgccgggtt tttctgcctg aatcacggta
     3421 cgaacattac cggttagcca aaaagattga cacgtcccat caaggctaag aggcggcgtc
     3481 aaatgaccat ttttacgtac tagcggataa ataatacgcc catcagcgta ggaaggtgtc
     3541 atgtagcagt tatacatttt gcctttactt atcacaggct gaaagtagct ttcaccgcga
     3601 tcgatcagtt caatcgtttt tcctttccag cgatacacat tgacgccatg gctgcagcaa
     3661 ccgccgcgcc aatagctgac aatctgttta tgttcagcat cgatctctgg tgaagtgatc
     3721 tcctgataag acgcgggcgc atcaacataa cgctgcttgg cggggtcata gagccatgtt
     3781 tgtactggag catccggccc agcaagtaac tctgttacaa tcgatagatc cgggtagcca
     3841 tcaaaattga catcccccca ttgaggcata aacgggctac aggtgcccac cgaggcggta
     3901 tctaaggtct gtatgagttt accatcacgg tataatttta tcgccgaaat ggccggcgta
     3961 ttgccgcaat caatctcttt ggaagggtcg taaccccctg catcattcgt gttcgtgacc
     4021 agcacaatat caggggagtt tttaggtttg taatagataa gggcaacagg aaaatgtcgt
     4081 tttttatctg cggacgtcca ttcgccttta atctcactgc tggagatttc cgcattccag
     4141 taacccgaaa gcgcctttac gcgttcttca agatgcacct ctttatcctg gagtgagccg
     4201 cgtagaacaa tcactgcctt gtgctgattg caaggttcat agcagtaatg cccataaagc
     4261 gtgttaccaa atcgcgtgat attaacgttt accggtttcc ccgcgatagt cccggtatag
     4321 tttcgctccc aggcgggtag ctccagcacc gtagcgcttg ccgcgtccat ccaaaagccg
     4381 atggcgagta acgttggcaa tctatatttt attttgccca tttcccttat ccctgtaggc
     4441 attacaaccc aaaaaccagc aacgattgtg ctggtttttc agatgaatag caaaaaggtg
     4501 gggcattagc accggatgac gactacgcct tatttttcct gtcgcacatt gaatatcaaa
     4561 agaaattctt aagatctggt cagcgtagca tcatcgggca gatttctgaa ttgtgaaatc
     4621 ttattcgact tcacgaacat ccacacgcag ctctttcggt acttcgaaaa caatattttc
     4681 ttcgcgaccc tcaagcgtga cagcttcgcc gccgccaaac tcccgcagac gcgcaataac
     4741 attctgcacc agaatatccg gcgcggaagc gccagcggtg acgccgacac aggcggcgtc
     4801 tttcacccac gcctcctgga tatccgccgc atcgtcgata agaaacgcgg ttcttcccat
     4861 ccgttgggcc agttccgcca atcggttaga gttagaagag tttttcgagc caaccaccag
     4921 cactacgtca gcctgctcag ccagcgcccg caccgcttcc tgacgattag tagtggcata
     4981 gcaaatatcg tctttgcgcg ggccgacgat tttcggaaag cgtttacgca gcgcatcaat
     5041 cacatcggac gtatcgtcca cggaaagcgt ggtttgcgtc atgaaggaga gcttgccttc
     5101 atttttgaca ttcagcgtcc agacgtcctc tggcgactcc accaggtaca tccccccttc
     5161 cggattgctg tactggccca tggtgccttc cacttccggg tgcccggcgt ggccgatgag
     5221 aatagattct tcaccgcgac ggctggcgcg cgccacttcc atatggactt tcgtcaccag
     5281 cgggcaggtg gcgtcaaaaa cggtaagatc gcggcttttc gcctcgttac gcaccgcctg
     5341 ggaaacccca tgagcggaga agatcagaat ggcgccatcc ggcacttcgc taatttgctc
     5401 tataaagatc gctccgcgct ggcgcaggct gtccactaca tagcggttat gcacgacttc
     5461 gtgccgaacg taaattggcg cgccgtaaat ggcgagcgca ttttcaacaa tgctgatagc
     5521 gcggtctacc ccggcgcaaa aaccgcgtgg gttggccaac aggatctgca tgtttatgcc
     5581 tccagcgccg gatcgatttc cagcacttca atatcaaagt gaacggtatg cccggccagc
     5641 ggatggttaa aatcaacggt aatcgagtcg ccgttgattt cgcgaatcac gccaggcatt
     5701 tcgctgccat ccattgcggt aaaaagcata atcgccccga cttccggttc gcccgccgcc
     5761 ataaactcac ggcgcgagaa atactggatc aagtccggac tggggacgcc aaacgcggcg
     5821 tcaggctcca gcgaaaacgc tttcttttcc ccttctttca accccagaag ctgctgctcc
     5881 agaccttcgg aaagcgaggt atcgccaaga cggaacaggg ctggcttgcc gttattgcgg
     5941 gtagattccg ccgttgagcc atcatccagt ttcagggtga agtgaacgag gatcgcgctg
     6001 ttgctctgta cggatttaga catgcaaatt gctcacgtgt tttgcccgga ggcacaaaga
     6061 acgataaaac cgtaggccgg ataaggcgtt ttcaccgcca tccggcacca cgtttgcctg
     6121 atggcgctgc gcttatcagg cctacaaaac cggataagcg caacccggta tttacgctta
     6181 tgcctgctct ttcgctgtcg gcttcggcaa aaagccttcc agtactatca gcgcagcacc
     6241 gatacaaatt gccgtatcgg caaggttgaa cgtcgcgaaa tgccagtcgc cgacgtaaaa
     6301 atcgatcata tcgacaacga agccgtgcca cagacgatcg aacaaattac ccagcgcgcc
     6361 gccaataatg agcgcataag cgatgttatt cagcttctgc gtcgctttcg agcgatacat
     6421 catcaccaaa agaattacgc agatccctat cgcaatcccg gcaaagaacc agcgctgcca
     6481 gctgccgcta tccgccagga agctaaaagc cgcgccgtag ttacgcgcat aatgcagatt
     6541 aagcgacggg aacagcccta ccgtatcccc cagagcgaaa ttctggagga tcaggtattt
     6601 gctgcccaaa tcgataatca gcacgactac taccagccat agccagcgta gtcctgttga
     6661 acagagtggt ttactcatca ggcaaattta cgttgttcgc cattaccggc gatgttgctg
     6721 acacagcgtc cgcagatatc tgcatgttcc gccaccttgc cgacatcagt agtgtagtgc
     6781 cagcagcgcg gacacttatc accctcggca cgcgttacca ctgcctgaac tgtcgtatta
     6841 ccagcattgt actgaatatt ttcatcatca ataccccccg cttgctcaga aatcacgaac
     6901 tgggaagtaa tgaagataaa tctgacctct tcgcccaaca gtttcagctt cttgatcgta
     6961 ccgttagcat cgtcagcata tttcagcgtc acttttgctt ccaggttcga tttgatgcca
     7021 ttggccttct gattttccag ctctttgttg acctggtcct tgatatagcg gacatcgtcc
     7081 cagaatgcgt cattaaattc ttcattctct tccaggccaa acaacccgtc gtaccattcg
     7141 ccggtgaaga catatttttc acgctcgccc ggcagatagc cccagatttc atcagccgtg
     7201 aaggacatga tcggcgccat ccagcgaacc agcgcctctg cgatatgata cagcgcagtc
     7261 tggcagctac gacgcgcgac gctatcggcc ttcgcggtgt actggcggtc tttgatgatg
     7321 tcgaggtaga acgaccccat ttcaacggag cagaagcgca tcaggcgctg taccacttca
     7381 tggaagtcgt aagcttcgta tgccttcaga atctcttgct gcgccgtttt cgcgcagccc
     7441 accgcccacc tgtccagcac caccatctct tccggtttga ccatatcggt ggccggattg
     7501 aagccattga ggttcgccag caggaagcgc gcggtattac ggatacgacg atagctgtca
     7561 gcagcacgtt tcaggatttc gtcagagacc gccatttcgc cggtatagtc agtagacgcc
     7621 acccacagac gcaggatatc cgcgcccagt ttattcatca catcctgcgg cgacacggtg
     7681 ttaccgatgg acttggacat cttgcgcccc tgaccatcga cggtgaagcc gtgagtcagt
     7741 acctggcggt atggcgcttt gcctttcatc gccacgctaa tcatcaggga ggacataaac
     7801 cagccgcgat gctggtcaga cccttccaga tacatatcgg cagcgtgacc ggcgaattcc
     7861 ggacgggcgt caaccacgga gtaactggtg gaaccggaat caaaccaaac gtccaacgta
     7921 tccggaactt tctcatattg atcagcatct tcgccgagga tctctttcgg gtcgagatcc
     7981 caccacgcct ggataccgtc aacttcaacg cgtttcgcca cctcttccat cgccgccaga
     8041 gtacgctcaa tcggcagcag ctcctgcgtt tctttatgca cgaacagcga catcggtacg
     8101 ccccaggtac gctgacggga gatacaccag tcaggacggt tagcgaccat tgattcaata
     8161 cgcgcctgac cccagtccgg gatccactga acgcctttga tctctttcag cgactgttga
     8221 cgaagccctt ctttatccat gctgacgaac cactgcgggg tcgcgcggaa aatgatcggc
     8281 gttttgtgac gccaacagca cggatagctg tgctgcattt tttcgacatg cagtagcgcg
     8341 cctttttctt tcagcagttc aataacgata tcgttcgctt tgaagacgtt aacaccgtca
     8401 agcgttggat atgtgcctgg caggtaagcg ccgtccggcc caaccgggtt agccgtttcc
     8461 agaccgtatt tctgaccaat cacatagtcg tccgggccat ggccaggtgc ggtgtgaacg
     8521 gcaccggtac cagcatccag ggtgacgtga tcgccgagga tcgccggcac gtcaaagccc
     8581 ataaacggat gggtaaagcg cagcagttcc agctccgcgc ctttgacggt gccgagaatg
     8641 gtgtattcag ccgcgccaat acgctgtatg acgctttcaa ccagatcttt cgccagaatc
     8701 accgcctgac cgtcgatctg caccagcgca taatcaaagt ccggcgccag ggagatggcg
     8761 cggttagccg gcagcgtcca cggcgtggtg gtccagataa ccagcgacac agggccgctc
     8821 acgcccggca aaccaaactt cgctttcacc gcatcctgat cgacggcacg gaacgccacg
     8881 tcgatagacg gcgacgtttt gtcgtaatat tcaacttccg cttccgccag cgcggaacga
     8941 cagtcaacac accagtgcac cggcttagcg cctttgtgca gatgaccgtt tttgataatt
     9001 ctgcccagcg cgcggatgat gttggcttcg gttttgaagt ccatggtcag gtacggatgc
     9061 gaccagtcgc ccaacacgcc cagacgaatg aagtctttac gctggccgtc aacctgagtg
     9121 gcggcatatt cgcggcactt ggcgcggaat tcagcggcgg tgaatttctc gcccggctta
     9181 ccgaactcct gctcgacttt cagctcgata ggcagaccgt gacagtccca gcccggcacg
     9241 taaggcgagt caaatcccga cagtcctttg gacttcacga taatgtcttt cagaatcttg
     9301 ttaactgagt gaccaatatg aatgctgcca ttcgcatatg gagggccatc atgcagaatg
     9361 aaggtttttt tgcctttttt ggccgcacga atgatgccgt acagatcatc atcggtccaa
     9421 cgcgccagca ttcccggttc acgcttggcg aggtcgccgc gcatcgggaa ccctgtttcc
     9481 ggcaaattca gggtcgattt atagtcactc atcagattct cggttccgta tttcggtttg
     9541 ataaacaccg tcagggttac acctgcccgg ctagcccaaa aaacttgcgg gccgttaact
     9601 catcgcgtgc gatttgcgct tttagctcat caagcgacgc aaatcgctgc tcattacgta
     9661 tctttttacg cagtattaca tctatatggc gaccgtagag gtccattaca acgtccagca
     9721 gatgcacttc cagttgttga cgcacgccag ccaccgttgg acgagtgcca atgttcgcta
     9781 cgccgggtaa cggcttatcg ccaagcccgg tgacttccac cgcatagacc ccttttaccg
     9841 gtgagacctg acggcgcagc ggtaagttcg ccgtcgggaa gccaatggta cgtcccagct
     9901 cgtcgccatg aacgacacgc ccggaaatag taaagggatg tcccagcaga ctttcggcaa
     9961 gcgccaggtt atcttccgcc agcgcctgtc tcactgcggt actactgata cgcacgccgc
    10021 cttcacaaaa ggtttgggtg ctggaaaccg caaaaccata ctccgccccc gccttctgta
    10081 ataacaagaa atcgcccgcg cggctagcac caaagcggaa atcatcgccg acggcaagaa
    10141 attgcacgcc aagtcgctcc accagcagtt cgctgataaa cgtttgcgcc gtcaaagcgg
    10201 caaagcggcg atcgaatttc acgcatagca catagtccac gccgcactgc gccaggtaat
    10261 gcagtttttc acgcaggcgc gtcaggcggg cgggcgcttt atccgttgcg aacagctcca
    10321 gcggctgcgg ttcgaaaatc atgaccacca ccggcagacc gcgtctgcgt ccttcttcct
    10381 gcaaaccctg cagtagagcg cgatgccccc gatgtacgcc gtcgaaatta ccaatggtca
    10441 gcacacaccc atgcggggcc tgactgagat tatgtatgcc gcgtatcagc ttcatgtctg
    10501 actcaaaaca gtgaaaatcg caagagtata ccttgtacag cggttaaggt taaccggcga
    10561 ttgccctgat gaaacataaa gaagatgctt ttcatcgcca tgcggcaaac tccgccccaa
    10621 aacccgccgc ttaatgcaat ttttctcatg gaaaggctgt attcacagca cgcaagctgg
    10681 tagaatcctg cgccatcact acgcaacgag tgctgcaatt taaacggcgc ttatttgcac
    10741 aaatccattg acaaaagaag gctaaaaggg catattcctc ggcctttgaa ttgtccatat
    10801 agaacacatt tgggagttgg accttggcta atatcaaatc agctaagaag cgcgccgttc
    10861 agtctgaaaa ggctcgtaag cacaacgcaa gccgtcgctc tatgatgcgt actttcatca
    10921 agaaagtata cgcagctatc gaagctggcg acaaagctgc tgcactgaaa gcatttaacg
    10981 aaatgcaacc gatcgtggac cgtcaggctg ctaaaggtct gatccacaaa aacaaagctg
    11041 cacgtcataa agctaacctg actgcacaga tcaacaaact ggcttaatcg cctgcttgtt
    11101 atcagctttg tagaaaaacc cgcgtaaagc gggttttttt atgcctgcta tctgccgttt
    11161 ttctcgtcaa ccgctggcgc tgacctcact cgttcacgct cttcctgtgc cagcctattt
    11221 tttcagctat ccctccctta gtcacgtaat acttgaaagt tattttcttt cactgttttc
    11281 cttttcttat ttcattactg aaaaaactgt gaccacctta gcaaataaaa acatcgctca
    11341 tttaaaaact aataaacgca atcctgatgt aagatttaat aattgattga tgccgtcggg
    11401 ttaactactt ttcatgtaca ccttacttac tcattttaat ctgaggttaa attcagaaac
    11461 gacataaaaa taatattcaa aacttgctta gaaagtagag gttgtttttc tgggcgtatc
    11521 gtaccaatat cggagttatc attatgagtt ctgtcattga ggatacccag ccttccgggt
    11581 cagcatcatt gtctttacta cagcgtatta gctacggctc tttggatgtg gcgggtaatc
    11641 tgctatactg cttcggttca acgtacattt tatatttcta tacagacgtt gcgggcatta
    11701 gccttgccgt agcaggcatt atcctgctgc tggcgcgtat tgtcgatggc atagacgccc
    11761 ctatatgggg gatcatcatc gataaaacgc gttcacgcta cggtaaatgt cgtccctggt
    11821 ttttatggtt accgctgcct tttgcggtat tcagcgcgct gtcattttgg tctcctgata
    11881 tcagtataac aggaaaagcc atctatgcag caatatctta tatgattgcc agcattctat
    11941 ttaccggact taatacacca ctcagtgcaa tattacccct gatgacctta tctcccaagg
    12001 aaagactggt tttaaattcc tggcgaatga ccggtgggca aattggggtt ttattaatga
    12061 acgcgaccgc cttgccgtta gtcgcttttt taggtaacgg tgatgatcac gctggtttta
    12121 tttatacggc gattacattt gccattatat cttgcgcgct aacgctcttt gcgtttaaaa
    12181 acattcgtga aatggatgcg gataaaatac agcatgaacc taagttgccg atgaaaaaaa
    12241 gtttcgcggc gatgaaaggt aactggccat ggattctgat ggtgctggct aatctgatct
    12301 tctggattgc cctacagcag cgctccacga ccattgtcta ttatctgacc tacaacctcg
    12361 accgtaaaga tctggtgccg ctgattaaca gcctggcgac gattcagatc ctgtttatca
    12421 tcgctatccc cttctttagc aaatacctgg ctaaaacctg gatatgggta ggcggtctgc
    12481 tggtcgccac gtttggcggc gtcatgatgt ggctggcagc ggacaacatt actttcctca
    12541 tcgccgcctg gatactcggc aatatcggca gcggtatcgc ctgctcaatg ccatttgcca
    12601 tgctgggctt cgccgttgat ttcggcgcct ggaagaccgg tattaaggct accggcattc
    12661 ttatcgcctt cggcagtacc ttctgcatca agatgggtag tggcctcggt actgctttag
    12721 ccgcctggat catgaacagt tttggctatg tccccaacca tgcccagagt gctgcgggtc
    12781 tggagggaat tacctgggcc tttatctggg cacccgccct actcttcgcg ctcgcagcga
    12841 tcccattact tttctttcgc aaatacgaag cgatggaaga gaagattcgc cacgatctgg
    12901 aaaccatcaa ctcataacgt tctttacctt caccctcgaa tataggaggc accaccatgc
    12961 catttatgca acaagaccca cgtcgtctgg tctggcagca aaacgatcgc tatttatgga
    13021 ttgaaccctg gggcgagaac agcctacgcg tacgcagtgg ccgtcatctg ccggtaatga
    13081 gaaatgaaga ctgggcattg actgagccag tcgcagaaag ccagtgccac attgattatg
    13141 agcaccacca agcaacgctg accaacggca aaattatcgc tatcgtcaat caaaaaggac
    13201 aagttacctt ttaccgccat ccacacaaac ccctgttgca ggagttttgg cgcctgcggg
    13261 gcgaaattgg cgaggatgaa tcatctcacg gccagtacgt cagcgcactc aaccttgagg
    13321 gacgcgagtt ccgcccgatt cagggtggga aatattcact gaaagcccgc ttcgaagcca
    13381 ccgaagggga aaaaatttat ggcatggggc agtatcaaca ggccaacctg gatctcaaag
    13441 gatgcgtgct tgagctggcg caacgtaact cccaggcctc agtaccattt atgctctcca
    13501 gtctgggcta cggattttta tggaacaacc cggcagtcgg acgcgtaacc tttgcccaaa
    13561 acgttaccga atgggaagcg caggtcagcg aacagttaga ctactggatc acggctggcg
    13621 ataccccggc agaaattggc cgggcttacg cgctggctac cggcacgccg ccgatgatgc
    13681 cggactacgc catgggcttc tggcagtgca aactccgtta tcgtacgcag gaagagctgc
    13741 tggaggtcgc ccgcgaatat aagcgccgca atctacctat ctcggtgatc gttatcgact
    13801 tctttcactg gccgaatcag ggtgactgga tgttcgatgc gcgcgactgg cccgatcctg
    13861 atgccatgat tgccgagctg aaatcgctgg gaattgagct gatggtctcc gtctggccga
    13921 cggtggataa ccgcaccgaa agctatcggg agatgcgtga aaacggctgg ctggtacaaa
    13981 cggaacgtgg cttgccgatc aatatggatt tcctcggcaa taccacttac tttgatgcga
    14041 ctcatccggg cgcgcgcgac tatgtctggg gcaaagccaa acgcaactat cacgataaag
    14101 gcgtgaagct attctggtta gatgaagccg aacctgagtt cagcgtttac gactacgaca
    14161 actatcgcta ccatgccgga ccggtactgg aagtgggcaa tatctaccca cgcatgtacg
    14221 ctaaaacctt ttttgatggc atgaaagccg atggcgaaga ccaggttatc aacctgctac
    14281 gctgcgcctg ggccggcagt cagaagtacg gcgctctggt ctggtcaggg gatattcact
    14341 cctcgtttag atcgctgcgc aaccagtttg ccgccggact caatatggga atagcaggga
    14401 taccgtggtg gacgacggat atcggcggtt tccatggcgg taatattcac gacccgaaat
    14461 tccatgaatt gctgattcgc tggttccagt ggggcgtctt tagtccggtg atgcgtctgc
    14521 acggcaaccg cgatccgcaa attttacccg cgcaaccgta tcgggatggt atcgcccagt
    14581 gccctacagg tgcgccgaac gaggtctgga gctacggtga ggaagtatgc gacgtactga
    14641 caggttgcct agcgttgcga gaaaaactca agccctatat caaagcgctg atggaggaaa
    14701 cccataagca caatacgcca gtgatgcgcc ccctgttctt tgaattcccc gaacaggaaa
    14761 caagttggac aatcaccgac cagtactgtt ttggtcctga cctgctgatc gcccccgtca
    14821 tgcatgaagg tatgcgcgaa cgtgatgtct ggctaccaga aggggaaaca tggacggatc
    14881 ttgcgaccgg tgaaagctat tcaggagggc agacgctgca ttacgctacg ccactgaaca
    14941 gaattccggt gtttatccgc gaaggtgggc agtaccgtag cctactgaac ttgtagaatg
    15001 attccggctg cgggttagtt ccgcagccgg aagtattacg gtaggtatgt ctactgtagc
    15061 ttaaacaatg ccgagtagtc cgcattgcaa atacgctgca ccgccggatg ctggatcatt
    15121 ctctcggcaa aaatcgcatg atattcttcc atgacattct ccacgcgccc aatctctatt
    15181 accgactcat cggcataaaa atccagcgaa taaaggctcg gcgccacaaa aatcgcatca
    15241 tgcgtcgcgc caaacgcctt cattaaggcc gcgtcatcaa attcaccgag gatctcaacc
    15301 tgcaacccct gcgaattaaa ccagttcaac aacttacgcc ccagcattga gcgacgtccc
    15361 ggcaccagca accgtcgctc ttccaggcag gcaggaaacg ctttttcagg aagcggattc
    15421 gtacaccaga aactgacgct gcattcgccg attttgactg agaatagccc ctcctgctgc
    15481 gtggaatcta tcgggcagtc ggagataatc atatccagct tgtgctggct gagctgttcg
    15541 agcaacattt cgtgcgtgga ctcgaagcaa cgcagatgta tgggttcgtc caccaccacc
    15601 gccgcatcca gaacgctgct gaccagacgc ttggataaag catcggcgac gccgacatca
    15661 aacaacaggt ttgattcttt gcggtaattg acaatatcca gcatctcctg gcttagcgta
    15721 aacattttgt ccgcatagcg aaaaaccagc tcgcccagtt cgctgggttc aagaccgcgt
    15781 cccttacgtt taaatagctt cccctgtaaa cgctcttcca gggctttaat ttgaccagta
    15841 atggtttgcg gcgtcagaaa aagcgcctct gcggcgccca cgacagaacc ttctttatag
    15901 acatgccaga aataataaag atggttgtag ttaatatgag acatgctcat ttctctccct
    15961 gctcaatgtc gtaagggagc gatacatcgc tcccccttcc cttcgtactg gttatgccgg
    16021 cgcgttcaaa cgcgcgcgca accagctata ccccaccact gcggagagca atgaaccaat
    16081 caaaatgccc aatttcgccc agttaataag ttccggatcg atattgccaa atgccaggct
    16141 ggcgataaag atggacatcg taaagccaat gccacacaaa atgccgaccg ccatgatttg
    16201 ctgataagtg gtcccctgcg gcagatgcgc cagcttgaaa cgcagcgcca gccagcaaaa
    16261 caggctaatc cccagcggct taccaatcag cagaccagca ataattccca acggcagcat
    16321 ggaggtcaga ccgtccatcg tgacgccctg aagagaaacg ccggcattcg caaaagcgaa
    16381 gagcggcagg atcaggtatg cgacccacgg gtgcagaaca tgctccagac gcttggccgg
    16441 cgagcgtccg tgtttttctt tcagcggaat aaagaagccg acaatgacgc ctgccagcgt
    16501 cgcgtgaacg ccggacttca gtaccgccgt ccacagcact gccccgacca gaatatatac
    16561 ccctgtccgc ctgacgccgc acaggttcag cagcgccagc acggcaatcg cgaacgccgc
    16621 cacgcccagc gagacgatag aaagatcgct ggtataaaac agtgcgataa taatgatggc
    16681 gccgaggtca tcgatgatcg ccagcgccat caggaaaatt ttcagcgcca gcggaacccg
    16741 gctgcctaac agcgccagca cgcccagcgc aaaggcgata tccgtcgcgg caggaatagc
    16801 ccagccctca cgagtgaccg gatcggagta gttaaaggcc agatagagca atgctggtac
    16861 aatcatcccg ccgatggcgg caatcaccgg aaaagcggcc tggcgcagac tggctaacga
    16921 gccttgcatc agttcgcgct taacttccag gccaatcaac aggaaaaaca cggccatcag
    16981 cgcatcgttg atccacaaca gcatgttttt gttgatctca agcgccccaa cccgtagctg
    17041 aaccggcgtc tccagaaaat catgatacca tccactggtc gcgcccatat tggccatcag
    17101 catagccagc gcagcggcga tgatgagaat gatgccccca gaggcatcgc tgctaaaaaa
    17161 tcggtgcaga tgtttcactt tttattctct caatcaggtg aattcttcgg atctactatc
    17221 ttacctcgcc tgactcatcg ttaaaattag attatatatg atgaatagct cgttttttac
    17281 gaaatgaagt ccgacttacg ccggactttt ttagtgcagt cagtcattga tgatagaccg
    17341 ctacgcgtac agatccattt tatacacccg gaaactggta atatcgtagc gatagccttc
    17401 cccgttcgtt tccgcgtttt tgtagtaacc tgacgtcata gtcgcttcaa aaagcacggt
    17461 tttctccgta ggcgcaatct cctgtaaaat tagcagcccc atcgcctcgc tgcccgcctg
    17521 cggatcgata atatcgctct cgccaggctg gcaagagatg gcgcggccat tttcatcaaa
    17581 cgtgcagtcg gcaaaatgca ccacaatatt gccattctgc tggatcgctt tcgcgctaac
    17641 gcagctactg tagccacgcg cgcccagctc cttgccgtat tcaaatggcc gcataacggt
    17701 catctcattc atattcacca cgaaatggac aatgcggctg tagttatccg gcggtaacag
    17761 gcttttgctg tcatcacgcg aacggtagtt accgttatca aataccataa actccactat
    17821 acccggcgta ttattggcga tttcaacgac gttatgctgg ccccacgtcc aaaagtcacg
    17881 gtcggccgcg tcgatatcct cctgtttgct aaagtcataa agcgccacac cttcactgtc
    17941 gaccggggtt aaaagataag gctgataagc gtcgtcccag tcttcatgcg ttgacaaaat
    18001 aaagcgtaac gcttgcgttt gcagatcgac gccaaacacc gcgctctgat gacgcccgga
    18061 cgcaattaac aactgattcg tctcattcac gtagctctgg tttatgtgca gccagtcttt
    18121 aaccgtcggg tcttctcccg gcgccgtacc tgaaggacgg gaaacccgcg tcgtatccaa
    18181 caccttcgcc atatcgtagt aagccgtctc cagtccggta gccagatcga caaccgatac
    18241 gccgtcttca ttggttttca aatcgtcggg ccgacccgag gtatattcag agggcgcaac
    18301 aatggtatta ctgtcccacg gccagataga atggtgaaat tggttatcga gattatagaa
    18361 tgtgtgaaga cgccccatca tgtcgaactc atacatatcc agataggtat ttttcgcttc
    18421 tgaagtggtg aggaaatggc cattatcaat tcgaacaaaa ttataagacg gataatcctg
    18481 agtaacgtac cagcgcacca gaccattctg atctaatgcg taattatagc gatcgaaatg
    18541 cgtaacaaaa taaaaccctg gcgccatctt gtccacatcg gtagcaggtt gcgtcacgtt
    18601 gataatcgga aaacctaata cgacctccgc ggaatctacc ggcggtaacg gctgtgtggt
    18661 gagcgtatag acggcaagcg gcgtatctgc ctgagaaaag acaatacggt tttcagtctc
    18721 cgctaccagc cccagaaccg gcaacagatt tgcgcctgcc gtaagggtgt aaagatgttc
    18781 taccggcatc gccgtttttg ccgcatcctg gaccgtgacc atgatctcag ccggttccag
    18841 actccagacg ccggcatagg cgcttaaagg tgccgtgccg taagggtcta acaacatgag
    18901 cgcattttct accgtattct cttgcgtgac ctgcgcaagg caattttcat aaatagcggt
    18961 atggttaagc actatttcat tattgatatc gataccctga ttaatcgccg gacgcggcgc
    19021 aggaaggaca acagacgttg cagttaacgt attcatgata aatctccagt gtattaatct
    19081 catcgcccct catggggacc acgaaaatta atactctgga tttttaagcc gtccgaataa
    19141 aataccgcaa caacacctca tcacactttt tattttagca attcagttac atgaagcgtc
    19201 atattcaaat tttaggtaat ccagtacggc aacaacattg ccaggagaca tccggttaag
    19261 atgcggcagg aagggatggt tgtgaacata gcgaataaac gccgtcgcgc tatttaacgt
    19321 cgcatgacgt aacaaactca cctttttatt tcctgtgaga ttgcatactg ccatcgcata
    19381 atcccgtgtg gaaaatgtac gccagacgtt gttgcgaatt ccgccgctca aaaacaaccg
    19441 cggagggaga tcgcgtttgg gcggcgtaac gcctctttca cgcacaaacg aaatatggca
    19501 gcgcccctga cgaagatagc taaaattcgc catcatacag ccgcccagaa taaagcattc
    19561 gtgatcgaga taatgctgga cattcaggga gcgctcatcc gtcaacgcct gaaccaactc
    19621 aaaatgtcga taagcaggta atacgggttt tactaacatc cccggatcgt ttttatataa
    19681 aatggcgggg ccgtaatcca catcaaataa tacattgcgg cgcatggtca gcgcctcttt
    19741 tcgctgcacc agatgcgcca gcgtgccgga cggaagtcgt tcttcgtaat cagaatgata
    19801 ttgataatcc gcttccaccg gttgggcgga gtaattcgtt gagatcgcaa cgaccttacc
    19861 gctctcctct tccgccgtca ccagcacata taagctgctg tcgccgccgt taaatttcac
    19921 acgaaacgcc cgcgtgctca tagcgatatc aaacgcggga aacacaaaat cgcgttccgc
    19981 ttgattagcg cgacgggaca gtttttgtaa ttcgcggcta aaacccgtgc tgtctatcgc
    20041 cagcgccgcg cgtatttcaa ctagcgacgc tccttcgcca atcaacgtgg caaggttctc
    20101 ttgtctggcg tcgctcctga tagcggtata ggagatgaac gttttattac actggcggca
    20161 atacatacgc cgttcacctt tagtggaaaa tccatatttt tcagcgacgt cccgccacaa
    20221 tgcggacagg acttcaccag acctttccag ggttgattcg ccgcctggcg aaaaagatta
    20281 agcgatctgg ctgagataat ggggaacaaa aaaccgcacg ctcgacagag aacatttttc
    20341 ccttgcggta gatagtctgg gctccccaga atccccagat ttttgcagcc tggcgttttg
    20401 caagcatcga cattaatgtg agaaaacata ttcactccct gcgaatacta ccttcaaaca
    20461 aatattgact ttatttctgc aagtgagatg cctttttcat acagggttcg catggcactc
    20521 atcgccgtcg cggtatgcga gaaaaaagcc tgataacctg cacacagata gttatgattg
    20581 gttgcgcctg acgcagaggg taaaaaacga tgtttcggac agccgccata gcaggcgaac
    20641 ttccattgac agcgatgaca ctcctgcgcc attgaacgct gtttatcgct gccgaactgg
    20701 cgattttgtt cgccctgatt catttgacgc agcgtcttct ggtggatatt ccccagttta
    20761 aattgcggat atacgaagtg atcgcagtta taaacatcgc cgttcatttc catcgcaaac
    20821 gcgctgccgc aggtgggagc aaaaacgcaa acctgcggcg gcaggccgca ccaggccgcc
    20881 agcgtctgtt caaatagctg gatgccgata tcgccgatat cctcacggat ccagatatca
    20941 aataccgcat tcagaaactg accaaattgc aggctatcga ccgaccacgg cgtcatcgcg
    21001 atatgtttat cctgcggctg cgccagccca ttttccccac agcgttcaac taaagggata
    21061 aattgcatat agcggctacc aacgcttttc aggtagcgat agacctgaac aggatgatgc
    21121 atattggtac ggttaaccac cgtgagggta ttaaattcta cgtcgtgctg cgccagacaa
    21181 cgcaccgcat tttctacttt ttcatgcgtc ggctttccgg agcgcgtcac tcgccattca
    21241 tcgtgtaacg cggcatcgcc atcaatagag acgccaacca gaaaatcatg ctcccggaag
    21301 aaggtcgccc agtcatcgtt gatcaggatg ccgttggtct ggaaggtatt gacgatggtt
    21361 ttgccgccac aatagcgctg ctgaaattca acggctttac gataaaacgg gatgcccatt
    21421 aatgtgggtt ccccgccctg ccacgcaaaa atgacctcat caatatcctg tgcggcaatc
    21481 tgctgcctga tgaagagttc gagggtctct tccgacattt tgtaatggtt ttttcgatcc
    21541 ggatagagct tttctttctc cagataaaaa cagtacttac agtcaaggtt acacaccgat
    21601 ccggttggtt taaccatgac ctgacaactt ttcccaaaca tcattacctt ccctgaaata
    21661 aaagaacctg atccggcaca gagtgaccgg atcaggtggg catcgcccta agtggcatac
    21721 ttaatttttt ataattattc cattagcccc aggtgacagg cgtcggctta tcgccacggg
    21781 ctttcatcag cgaatcgtta tcaatatcct ttttatactt caggaactta ccgtaaagct
    21841 gtttctcaat ctgcggctgt ttaccaattt gattgagcgt ctcgaaacga tcggttttca
    21901 ggttatagag atatttaggt ttattctggc gatcgatgat catcttccag tcgccgtcgc
    21961 ggatcgccca ctcatccgtc ggatcgtcct ggaacggcat atcgataccg aagatcagcg
    22021 gtttctggcg ttttaacgtc ttgtccttca ggagcggaac taaagactga ccgtcgtagg
    22081 tacgatcggt cgggagttta aagtccatca tgttggccag cgtcggcaac cagtcaagac
    22141 catataccgg cgtgtccgtt accatcccct gtggaatgtg cttgccgtat ttgatgattg
    22201 ccggtacgcg aatgccgcct tcccacaggt tgtctttacg cccgcgcaga ccgtcggttt
    22261 ccccggccag tttcagctcg tataccttac gcgcttcgcg cgtgacaggg ccgttgtcgc
    22321 tggtaaagat gacgatggtg ttatcttcct cgcccatcgc cttaatttta tccagcactt
    22381 taccgacctg ctcatccatg tagctgatat tggcgtaata ttcgccggtg ccgcgccacg
    22441 gtttgtctgc ccagtcgccg tagaacagat ccggatgctg cttctggtag tcggtcatgt
    22501 actgcgaata catatcaagg tattttttcg gcgacgccag cgggctatgg acttcggtaa
    22561 aggcgacata taagaagaac ggattatcgt ctttcttatt atccagccag ttcaccactt
    22621 cagagctcac aaactcgccg ctcatcttat ctgcgcggcc aatatgttgg ccattacgaa
    22681 tccaccccgt aggatgcacc acgccatagc gcgggcgctc cttggcgtta tccagcgtag
    22741 catcggtgac aaatcccgcc ggattaacca acgtatagtc aaagcccatg tctttcgcct
    22801 gcggctgatc ggtgcgatcg ccgcccgcat tcaggtgtaa tttccccatc atcgccgtat
    22861 cgtagccctg ctgttttagc agattggcga tagtcagttc attacgcccc agcgcaacat
    22921 ctttgccttc cggtatccag gaacggattc cggtacggaa cggcatacga ccggttaaca
    22981 ggcccgcgcg ggaaggagaa cacagaggcg ctggcgcata atagtcggta aacttcaccc
    23041 cctcctgcgc caatttgtct atgttaggtg ttttaacgat gcggtgcccg taggtggcga
    23101 gatcgccata ccctaaatca tccgccagaa taatgactaa gttaggacgc tttgcggttg
    23161 ccgcttgcgc ggttgataat acgcatccag cgcatagcgc caaccctatc atactggcaa
    23221 cgactgttct tttcatttca actcctttga gttatcgcac ggtctgatta cgatatattt
    23281 gccgatagac ccggctgcgg aatacagcct aaattaattg cactatatat attcgattta
    23341 tcttatat
//
LOCUS       DAJVBX010000055        23067 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.055, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000055 DAJVBX010000000
VERSION     DAJVBX010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 23067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23067
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.055"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            106..1782
                     /locus_tag="OPV72_001857"
     CDS             106..1782
                     /locus_tag="OPV72_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Kef family K(+) transporter"
                     /protein_id="HCR9914176.1"
                     /translation="MHHATPLITTIVGGLVLAFILGMIANKLRISPLVGYLLAGVLAG
                     PFTPGFVADTKLAPELAELGVILLMFGVGLHFSLKDLMAVKSIAIPGAVAQIAVATLL
                     GMALSAVLGWSLMTGIVFGLCLSTASTVVLLRALEERQLLDSQRGQIAIGWLIVEDLV
                     MVLTLVLLPAVAGMVEKGDVGIASLAVDMGITIGKVVAFIAIMMLVGRRLVPWIMARS
                     AATGSRELFTLSVLALALGIAFGAVELFDVSFALGAFFAGMVLNESELSHRAAHDTLP
                     LRDAFAVLFFVSVGMLFDPLVLIQQPLAVLATLAIIVFGKSIAAFFLVRMFGHSPRTA
                     LTIAASLAQIGEFAFILAGLGMALNLLPQAGQNLVLAGAILSIMLNPVLFTLLEKYLA
                     KTETLEEQTLEEAIEEEKQIPVDICNHALLVGFGRVGSLLGEKLLAAGIPLVVIETSR
                     TRVDELRERGIRAVLGNAANEEIMNLAHLDCARWLLLTIPNGYEAGEIVASAREKSPD
                     IEIIARAHYDDEVKYITERGANQVVMGEREIARAMLELLETPPAGEVVAS"
     gene            complement(1831..3135)
                     /gene="gsk"
                     /locus_tag="OPV72_001858"
     CDS             complement(1831..3135)
                     /gene="gsk"
                     /locus_tag="OPV72_001858"
                     /EC_number="2.7.1.73"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inosine/guanosine kinase"
                     /protein_id="HCR9914177.1"
                     /translation="MKFPGKRKSKHYFPVNARDPLLQQIQPEQETNASWVVGIDQTLV
                     DIEAKVDDDFITRYGLSAGHSLVIEDELAEKLYQELTRENLITHQFAGGTIGNTMHNY
                     SVLADDRSVLLGVMCSNIEIGSYAYRYLCNTSSRTDLNYLQAVDGPIGRCFTLIGESG
                     ERTFAISPGHMNQLRAESIPEAVIAGASALVLTSYLVRCKPGEPMPDATMKAIEYAKK
                     HNVPVVMTLGTKFVIADNPQWWQAFLKENVSILAMNEEEAEALTGENDPLLAADKALD
                     WVDLVLCTAGPIGLYMAGFTEEEAKRKTQHPLLPGAIAEFNQYEFSRAMRHKDCTNPL
                     RVYSHIAPYMGGPEKIMNTNGAGDGALAALLHDITANSYHRSNVPNSSKHKFTWLTYS
                     SLAQVCKYANRVSYQVLNQHSPRLTRGLPEREDSLEESYWDR"
     gene            3288..4259
                     /gene="aes"
                     /locus_tag="OPV72_001859"
     CDS             3288..4259
                     /gene="aes"
                     /locus_tag="OPV72_001859"
                     /EC_number="3.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl esterase"
                     /protein_id="HCR9914178.1"
                     /translation="MKPENKIPVLTRLSDEMTAVVNFQQPGLPPWPADGDIETQRQYY
                     LLERSFWNADAPSMTTRTCAVSTPYGDVTTRLYSPQPTSQATLYYLHGGGFILGNLDT
                     HDRIMRLLARYTGCTVIGIDYSLSPQARYPQAIEETVAVCSYFSQHADEYSLNVEEIG
                     FAGDSAGAMLALASALWLRDKHIRCGNVIAILLWYGLYGLQDSVSRRLFGGAWDGLTR
                     EDLDMYEKAYLRNDEDRESPWYCLFNNDLTRDVPPCFIASAEFDPLIDDSRLLHQTLQ
                     AHQQPCEYKMYPGTLHAFLHYSRMMTIADDALQDGARFFMARMKTPR"
     gene            complement(4256..5218)
                     /gene="hemH"
                     /locus_tag="OPV72_001860"
     CDS             complement(4256..5218)
                     /gene="hemH"
                     /locus_tag="OPV72_001860"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HCR9914179.1"
                     /translation="MRQTKTGILLANLGTPDAPTPEAVKRYLKQFLSDRRVVDTPRLL
                     WWPLLRGVILPLRSPRVAKLYQSIWMDGGSPLMVYSREQQQALAARLPDTPVALGMSY
                     GSPSLESAVDELLASDVDHIVVLPLYPQYSCSTVGAVWDELGRILARKRRIPGISFIR
                     DYADDGAYIDALAKSARESFARHGEPDLLLLSYHGIPQRYADEGDDYPQRCRDTTREL
                     VSALGLPPEKVMMTFQSRFGREPWLTPYTDETLKMLGEKGTGHIQVMCPGFAADCLET
                     LEEIAEQNREIFLEAGGKKYAYIQALNATPEHIDMILKLTAPYR"
     gene            complement(5448..6092)
                     /gene="adk"
                     /locus_tag="OPV72_001861"
     CDS             complement(5448..6092)
                     /gene="adk"
                     /locus_tag="OPV72_001861"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007706188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HCR9914180.1"
                     /translation="MRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKSGSE
                     LGKQAKDIMDAGKLVTDELVIALVKERIAQEDCRNGFLLDGFPRTIPQADAMKEAGIV
                     VDYVLEFDVPDELIVDRIVGRRVHAASGRVYHVKFNPPKVEGKDDVTGEDLTTRKDDQ
                     EETVRKRLVEYHQMTAPLIGYYQKEAEAGNTKYAKVDGTQAVADVRAALEKILG"
     gene            complement(6508..8382)
                     /gene="htpG"
                     /locus_tag="OPV72_001862"
     CDS             complement(6508..8382)
                     /gene="htpG"
                     /locus_tag="OPV72_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003903109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HtpG"
                     /protein_id="HCR9914181.1"
                     /translation="MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAAD
                     KLRFRALSNPDLYEGDGELRVRVSFDKDKRTLTIADNGVGMNRDEVIDHLGTIAKSGT
                     KSFLESMGSDQAKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGDKPENGVFWESAGEG
                     EYTVADITKNDRGTEITLHLREGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDG
                     ETVISWEKINKAQALWTRNKSEIKDDEYNEFYKHIAHDFTDPLTWSHNRVEGKQEYTS
                     LLYIPSQAPWDLWNRDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSNDLPLNV
                     SREILQDSTVTRNLRSALTKRVLQMLEKLAKDDAEKYQTFWKQFGLVLKEGPAEDHAN
                     QEAIAKLLRFASTHTDSSAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKNSPHLELL
                     RKKGIEVLLLSDRIDEWMMNYLTEFDGKAFQSVAKADESIEKLADEVDENAKEAEKAL
                     EPFVERVKTLLGDRVKEVRLTHRLTDTPAIVTTDADEMSTQMAKLFAAAGQSVPEVKY
                     IFELNPDHVLVKRTADTKDEAQFKEWVELLLDQALFAERGTLEDPNQFIRRMNQLLVS
                     "
     gene            complement(8493..9098)
                     /gene="recR"
                     /locus_tag="OPV72_001863"
     CDS             complement(8493..9098)
                     /gene="recR"
                     /locus_tag="OPV72_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HCR9914182.1"
                     /translation="MQTSPLLTQLMEALRCLPGVGPKSAQRMAFTLLQRDRSGGMRLA
                     QALTRAMSEIGHCADCRTFTEQDVCNICSNPRRQENGQICVVESPADIYAIEQTGQFS
                     GRYFVLMGHLSPLDGIGPDDIGLDRLEQRLASEKISELILATNPTVEGEATANYIAEL
                     CAEAGVEASRIAHGVPVGGELEMVDGTTLSHSLAGRHKIIF"
     gene            complement(9098..9427)
                     /locus_tag="OPV72_001864"
     CDS             complement(9098..9427)
                     /locus_tag="OPV72_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001364632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HCR9914183.1"
                     /translation="MFGKGGLGNLMKQAQQMQEKMQKMQEEIAQLEVTGESGAGLVKV
                     TINGAHNCRRVEIDPSLLEDDKEMLEDLVAAAFNDAARRIEETQKEKMASVSSGMQLP
                     PGFKMPF"
     gene            complement(9473..11401)
                     /gene="dnaX"
                     /locus_tag="OPV72_001865"
     CDS             complement(9473..11401)
                     /gene="dnaX"
                     /locus_tag="OPV72_001865"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HCR9914184.1"
                     /translation="MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFS
                     GTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDLIEIDAASRTKVE
                     DTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPAHVKFLLATTDPQ
                     KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLSRAADGSLRDAL
                     SLTDQAIASGDGQVSTQAVSAMLGTLDDDQALSLVEAVVDANGERVMSLINEAAARGI
                     EWEALLVEMLSLLHRIAMVQLSPAALGSDMAAIEQRMRELARTVPPGDLQLYYQTLLI
                     GRKELPWAPDRRMGVEMTLLRALAFHPRMPLPEPETPRQSFAPVAPTAVMTPPQVQQP
                     SAPAPQTSPAPLPASTSQVLAARNQLQRAQGVTKTKKSEPAAASRARPVNNSALERLA
                     SVSERVQARPAPSALETTPVKKEAYRWKATTPVVQTKEVVATPKALKKALEHEKTPEL
                     AAKLAAEAIERDPWAAQVSQLSLPKLVEQVALNAWKEQNGNAVCLHLRSTQRHLNSSG
                     AQQKLAQALSDLTGTTVELTIVEDDNPAVRTPLEWRQAIYEEKLAQARESIIADNNIQ
                     TLRRFFDAELDEESIRPI"
     misc_feature    complement(10076..10140)
                     /gene="dnaX"
                     /locus_tag="OPV72_001865"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00382"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="DnaX frameshifting element; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF00382"
     gene            complement(11515..12066)
                     /gene="apt"
                     /locus_tag="OPV72_001866"
     CDS             complement(11515..12066)
                     /gene="apt"
                     /locus_tag="OPV72_001866"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HCR9914185.1"
                     /translation="MTATAQQLEFLKNSIKSIQDYPKPGILFRDVTSLLEDPKAYALS
                     IELLVERYKNAGITKVVGTEARGFLFGAPVALGLGVGFVPVRKPRKLPRETIAETYEL
                     EYGTDQLEIHVDAIKPGDNVLVVDDLLATGGTIEATVKLIRRLGGKVTDAAFIINLFD
                     LGGEQRLEKQGITCYSLMPFPGH"
     gene            complement(12219..12596)
                     /locus_tag="OPV72_001867"
     CDS             complement(12219..12596)
                     /locus_tag="OPV72_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF454 family protein"
                     /protein_id="HCR9914186.1"
                     /translation="MQRTILIIIGWLAVVLGTLGVVLPLLPTTPFILLAAWCFARSSP
                     RFHAWLLYRSWFGGYLRHWQRYRAMPPGAKPRAIALILLTFGISLWLVNMMWVRVLLL
                     VILACLLIFMWRIPVIDEKQQKR"
     gene            12665..13192
                     /gene="priC"
                     /locus_tag="OPV72_001868"
                     /pseudo
     CDS             12665..13192
                     /gene="priC"
                     /locus_tag="OPV72_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001519637.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal replication protein N''"
     gene            13206..13373
                     /gene="rsmS"
                     /locus_tag="OPV72_001869"
     CDS             13206..13373
                     /gene="rsmS"
                     /locus_tag="OPV72_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pleiotropic regulatory protein RsmS"
                     /protein_id="HCR9914187.1"
                     /translation="MSLENAPDEVKLAVDLIVLLEENRLPARTVLRALEIVMRDYENK
                     LKSTEDDSQTE"
     gene            13443..14366
                     /locus_tag="OPV72_001870"
     CDS             13443..14366
                     /locus_tag="OPV72_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HCR9914188.1"
                     /translation="MERLPTTPHDAVFRQMLMQKEVARDFLAIHLPEDFLAICDLDSL
                     KLESGSFVEDNLRSRYSDILYSLHTQHGPGYVYALIEHQSKSDRLMAFRLMRYAIAAM
                     QRHLDAGHDTLPLVVPILFYHGPESPWPYSLNWHNMFVKPDMAKALYSHEFALVDLTI
                     MPDNQLLQHRRIAMLELLQKHIRQRDLSELLDPLITLLTQDHLTDAQLSVLINYMLKA
                     GNAAEPGALIRQLAQGAPQYKEQLMTIAEWLEEKGRTEGLRKGLEQGLAQGREAEARA
                     IARKMLANGLEPGLIASVTGITPEELSTLSH"
     gene            complement(14408..17770)
                     /gene="mscK"
                     /locus_tag="OPV72_001871"
     CDS             complement(14408..17770)
                     /gene="mscK"
                     /locus_tag="OPV72_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive channel MscK"
                     /protein_id="HCR9914189.1"
                     /translation="MTMLQLYKRSQHFVFITISVLIILLSCQSLAFARGQTNGDLPSK
                     ADVQNQLDTLNKQKDLSAQDKLVQQDLIDTLATLEKIERVKEETVQLRQKVAQAPEKM
                     RQATAALNALSDVDNDDEMRKTLSALSLRQLELRVAQVLDDLQNSQNDLAAYNSQLVS
                     LQTQPERVQNAMYTASQQIQQIRNRLDGNNVGEAALRPSQQVLLQAQQALLNAQIDQQ
                     RKSLEGNTVLQDTLQKQRDYVTANSNRLEHQLQLLQEAVNSKRLTLTEKTAQEAISPD
                     ETARIQANPLVKQELDINHQLSQRLIVATENGNMLMQQNIKVKNWLDRALQSERNIKE
                     QIAVLKGSLLLSRILYQQQQTLPSADELEDMTNRIADLRLEQFEINQQRDALFQSDAF
                     VDKLEEGHTSEVNDEVHDALLQVVEMRRELLDQLNKQLGNQLMMAINLQVNQQQLMSV
                     SKNLKAILTQQIFWVNSNRPMDWDWLKAFPQTLKEQFSAMKITVNWQKAWPAVFIAFL
                     AGLPLLLIAGLIRWRLKWLKAYQQKLAAAVGSLRNDSQLNTPKAILIDLIRALPVCLI
                     ILAIGLILLTMQLNISDLLWAFSKKLAMFWLVFGLCWKVLEKEGVAIRHFGMPAQLTS
                     HWRRQIVRISLALLPLHFWSVVAELSPLNLMDDVLGQAVIFLNLLVITLLVWPLCRES
                     WRDKESHGIRLVTVTILSIIPVALMVLTATGYFYTTLRLAGRWIETVYLVIIWNLLYQ
                     TVLRGLSVAARRIAWRRALARRQNLVKEGAEGAEPQEEPTIALEQINQQTLRITMLLM
                     LALFGVMFWAIWSDLITVFSYLDSITLWHYNGSEAGAAVVKSVTMGSLLFAIIAAMVA
                     WALIRNLPGLLEVLVLSRLNMRQGASYAITTILNYVIIAVGAMTVFGSLGVSWDKLQW
                     LAAALSVGLGFGLQEIFGNFVSGLIILFERPVRIGDTVTIGTYSGTVSKIRIRATTIT
                     DFDRKEVIIPNKAFVTERLINWSLSDTTTRLVIRLGVAYGSDLEKVKRVLLQAAMEHP
                     KVMHDPEPAVFFTTFGASTLDHELRLYVRELRDRSHTVDELNRAIDRLCRENDINIAF
                     NQLEVHLHNAKGDEVTEVKRDLNGGDLAPAAS"
     gene            complement(17889..18542)
                     /gene="acrR"
                     /locus_tag="OPV72_001872"
     CDS             complement(17889..18542)
                     /gene="acrR"
                     /locus_tag="OPV72_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter transcriptional
                     repressor AcrR"
                     /protein_id="HCR9914190.1"
                     /translation="MARKTKQQALETRQHILDVALRLFSQQGVSATSLAEIANAAGVT
                     RGAIYWHFKNKSDLFSEIWELSESNIGELEIEYQAKFPDDPLSVLREILVHILEATVT
                     EERRRLLMEIIFHKCEFVGEMVVVQQAQRSLCLESYDRIEQTLKHCINAKMLPENLLT
                     RRAAILMRSFISGLMENWLFAPQSFDLKKEARAYVTILLEMYQLCPTLRASTVNGSP"
     gene            18684..19877
                     /gene="acrA"
                     /locus_tag="OPV72_001873"
     CDS             18684..19877
                     /gene="acrA"
                     /locus_tag="OPV72_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter periplasmic
                     adaptor subunit AcrA"
                     /protein_id="HCR9914191.1"
                     /translation="MNKNRGLTPLAVVLMLSGSLALTGCDDKQDQQGGQQMPEVGVVT
                     LKTEPLQITTELPGRTVAYRIAEVRPQVSGIILKRNFVEGSDIEAGVSLYQIDPATYQ
                     ATYDSAKGDLAKAQAAANIAELTVKRYQKLLGTQYISKQEYDQALADAQQATAAVVAA
                     KAAVETARINLAYTKVTSPISGRIGKSSVTEGALVQNGQASALATVQQLDPIYVDVTQ
                     SSNDFLRLKQELANGSLKQENGKAKVDLVTSDGIKFPQSGTLEFSDVTVDQSTGSITL
                     RAIFPNPDHTLLPGMFVRARLQEGTKPTALLVPQQGVTRTPRGDATVLVVGADNKVET
                     RQIVASQAIGDKWLVTDGLKAGDRVVVSGLQKVRPGAQVKVQEITADNKQQAASGDQP
                     AQPRS"
     gene            19900..23049
                     /locus_tag="OPV72_001874"
     CDS             19900..23049
                     /locus_tag="OPV72_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit"
                     /protein_id="HCR9914192.1"
                     /translation="MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVT
                     ISATYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADI
                     AQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAA
                     NMKDPISRTSGVGDVQLFGSQYAMRIWMNPTELTKYQLTPVDVINAIKAQNAQVAAGQ
                     LGGTPPVKGQQLNASIIAQTRLTSTDEFGKILLKVNQDGSQVRLRDVAKIELGGENYD
                     VIAKFNGQPASGLGIKLATGANALDTATAIRAELKKMEPFFPPGMKIVYPYDTTPFVK
                     ISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINT
                     LTMFGMVLAIGLLVDDAIVVVENVERVMTEEGLPPKEATRKSMGQIQGALVGIAMVLS
                     AVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATMLKPVAKGDHGEG
                     KKGFFGWFNRLFDKSTHHYTDSVGNILRSTGRYLLLYLIIVVGMAYLFVRLPSSFLPD
                     EDQGVFLTMVQLPAGATQERTQKVLDEVTDYYLNKEKANVESVFAVNGFGFAGRGQNT
                     GIAFVSLKDWADRPGEKNKVEAITQRATAAFSQIKDAMVFAFNLPAIVELGTATGFDF
                     ELIDQAGLGHEKLTQARNQLFGEVAKYPDLLVGVRPNGLEDTPQFKIDIDQEKAQALG
                     VSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDINDWYVRGSDGQM
                     VPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMAMMEELASKLPSGIG
                     YDWTGMSYQERLSGNQAPALYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALL
                     AATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGLVEAMLEAVRMRL
                     RPILMTSLAFMLGVMPLVISSGAGSGAQNAVGTGVLGGMVTATVLAIFFVPVFFVVVR
                     RRFSRKSEDIEHSHSTEHR"
BASE COUNT         5195 a         6344 c         6163 g         5365 t
ORIGIN      
        1 atcgtatctt tttataaaac acaaccattt tttataaaca tcctgattga aattgtcata
       61 aactattacc cggagttttg gagtccagca accaaaggag acggaatgca tcacgctacc
      121 ccgcttatca ccaccattgt cggcggcctt gtgctcgctt ttattctcgg catgattgcc
      181 aacaaattgc gtatttctcc actggtggga tatctgttag cgggcgttct ggcgggacct
      241 tttaccccag gttttgttgc ggataccaaa ctggcgccgg agctggcgga gctcggcgtg
      301 attctattga tgttcggcgt cgggctgcat ttttcgctga aggatttgat ggcggtaaag
      361 tctatcgcca ttcccggcgc tgtcgctcag atagcggtgg cgacgctgct gggtatggcg
      421 ctttccgccg tgctgggatg gtcattaatg accggcatcg tttttgggct ctgtctgtct
      481 accgccagta ccgtcgtcct gctgcgcgcg cttgaggagc gacaactcct tgatagccag
      541 cgcgggcaaa tcgccatcgg ctggctgatt gtcgaagatc tggtgatggt gctgacgctg
      601 gtcttgctgc ccgccgttgc cggcatggtg gaaaaaggcg atgtcggcat agcctcgctg
      661 gcagtcgata tggggataac cattggtaaa gtggtggcgt ttatcgccat catgatgctg
      721 gtcggacgcc gcctggtgcc gtggattatg gcccgcagcg ccgccaccgg ctcgcgcgag
      781 ttatttaccc tttccgtact ggcgctggcg ttaggcattg cgtttggcgc ggtagaactg
      841 tttgacgtct cttttgcgct gggcgcgttc ttcgctggaa tggtgcttaa tgagtcggaa
      901 ctgagtcacc gggcggcgca cgatacgttg ccactgcgcg acgcctttgc cgtcctgttt
      961 tttgtttccg tcggcatgtt gttcgatccg ctagtcttga ttcaacagcc gctggcggtg
     1021 ttggcgacgc ttgccattat cgtctttggt aaatcgatcg ctgcgttttt cctggtgcgt
     1081 atgttcggcc actcgccgcg aaccgcgctg accattgccg ccagcctggc gcaaatcggt
     1141 gagttcgcct ttattctcgc cggactcggt atggcgctca atctgctgcc gcaggcggga
     1201 cagaacctgg tgctggcagg cgctattttg tcgattatgc ttaatcccgt actgtttacc
     1261 ctgctggaga agtatctggc gaaaaccgaa acgctggaag agcaaactct ggaagaggct
     1321 atcgaagaag agaagcaaat tccggtggat atctgtaatc atgccctgct ggtgggtttt
     1381 ggccgcgtag gcagtctgct gggagaaaaa ttactggcgg cggggattcc gctggtggtt
     1441 atcgaaacgt cccgtacccg cgtggatgaa ctgcgcgaac gcgggattcg cgccgtactg
     1501 ggcaacgccg ctaacgaaga aatcatgaat ctggcgcatc tggactgcgc ccgctggctg
     1561 ttattgacca tccccaacgg ttacgaagcc ggtgagattg tcgcctcagc gcgagaaaaa
     1621 agccctgata tcgagataat cgcccgcgcg cactatgatg atgaagtgaa atatattacc
     1681 gagcggggag ccaatcaggt agtgatgggc gagcgagaaa ttgcccgggc gatgctggaa
     1741 ctgcttgaaa cgccgcccgc gggtgaagtc gtcgccagtt aagggtttgc cggacggccc
     1801 gatgcgcgca gcgccatcgg gcaagccaga ttagcgatcc cagtacgact cttccaggct
     1861 gtcctcacgt tccggcagcc cgcgtgtcag acgcggagaa tgctggttca gtacctgata
     1921 actgacacgg ttagcatatt tacacacctg cgccagcgac gaataggtca gccaggtgaa
     1981 tttgtgctta ctggagttcg gtacgttgct acgatggtaa ctgttcgccg taatatcgtg
     2041 cagcagcgcc gccagcgcgc catcgcccgc gccgttggtg ttcatgattt tttccggccc
     2101 gcccatatac ggcgcaatat gcgaataaac gcgcagcgga ttagtacaat ctttatggcg
     2161 cattgcccgg ctaaattcat actggttaaa ttcagcaata gcccccggca gcagaggatg
     2221 ctgggtttta cgttttgctt cctcttcggt gaagcctgcc atatataacc ctatcggccc
     2281 ggcggtgcat aacaccaggt cgacccagtc cagcgcctta tccgccgcca gcagcgggtc
     2341 gttttcgccg gtcagcgctt ccgcttcttc ttcattcatt gccagaatcg agacattctc
     2401 tttgagaaac gcctgccacc actgcggatt atcggcgatc acaaatttgg tgcccagcgt
     2461 catgacaacc ggcacgttat gctttttcgc gtattcgatc gctttcatcg tcgcgtcagg
     2521 catcggttcg ccaggcttac agcgcaccag atatgaggtc aacaccagcg cggaagcgcc
     2581 agcgatcacc gcttccggaa tactttccgc ccgtagctga ttcatatggc cggggctgat
     2641 agcgaaggta cgctcgccgg attcgccaat cagcgtgaaa cagcggccaa tcggaccatc
     2701 taccgcttgc agataattca ggtcggtacg gctggaagta ttacacaggt agcgataagc
     2761 gtagctgcca atctcaatgt tgctgcacat cacgcccagt aacaccgaac ggtcatccgc
     2821 cagtaccgag taattatgca tcgtattgcc tatggtgccg ccagcaaact gatgggtgat
     2881 cagattttcc cgcgtcagtt cctgatacag cttctccgcc aactcgtctt ctatcaccag
     2941 agaatgcccg gcgcttaatc catagcgtgt aataaaatcg tcatccactt tcgcctcaat
     3001 atccaccaac gtctggtcga taccgacgac ccaggaggcg ttggtttcct gttctggctg
     3061 aatttgttgc aacaacgggt cacgcgcatt gacgggaaaa tagtgtttgg atttacgttt
     3121 accgggaaat ttcatgattg tgcttacgga tgaataacgg agcgctgcat ggtagcacat
     3181 tccccctgct gcgcgcgacg gacgatggcg tttcaatatc ggacgacgag atcgcagttt
     3241 ctccagccgc gttttttaca atggttcact ttcacaagga gcgttttatg aagccggaaa
     3301 ataaaattcc cgtactcacc cgactgtctg acgaaatgac agccgtcgta aacttccagc
     3361 aaccaggcct tcccccctgg cctgccgatg gcgatattga gacccagcgt cagtattatc
     3421 ttcttgagcg cagtttctgg aatgccgacg cgccgtccat gaccacccgc acctgcgccg
     3481 tctctacgcc ttatggcgat gtaacaaccc ggctctactc gccgcagccg accagtcagg
     3541 ccaccttata ctatctgcac ggcggcggat ttatcctcgg taatctggat acgcatgacc
     3601 ggataatgcg tctgctggcg cgttataccg gctgcaccgt gatcggtatt gattattcgc
     3661 tgtcgccgca agcgcgttat ccgcaggcca ttgaagaaac cgtcgcggta tgcagctact
     3721 tctctcaaca tgccgatgaa tactcgctca acgtggagga aatcggtttc gccggagatt
     3781 ccgcaggcgc catgctggcg cttgccagcg cgctctggct acgtgataag cacattcgct
     3841 gcggtaacgt tatcgcgatt ctgttgtggt atgggctgta tgggttgcaa gattcggtaa
     3901 gccgccgtct gttcggcggc gcgtgggacg gcctgacgcg tgaagatctg gacatgtacg
     3961 aaaaggccta tctgcgtaac gatgaagatc gggaatcgcc ctggtattgt ctgtttaata
     4021 acgatctcac gcgcgatgtg ccgccctgct ttattgccag cgcggagttt gatccgctca
     4081 ttgatgacag ccgcttgctg caccagacat tacaggcgca ccagcagccc tgcgaataca
     4141 aaatgtatcc cggcacgctg cacgccttcc tgcactattc gcgaatgatg acaatcgccg
     4201 acgatgcctt gcaggacggc gcacgcttct ttatggcgag gatgaagacg ccgcgttaac
     4261 ggtacggcgc cgtgagtttc agtatcatat caatatgttc cggcgtcgcg ttcagcgcct
     4321 gaatgtacgc atatttttta ccgcccgctt caaggaaaat ctcgcggttc tgttccgcta
     4381 tctcttccag cgtctccaga caatccgcgg caaaccccgg acacatgacc tgaatatggc
     4441 cagtcccctt ttcacccaac atttttagcg tttcatcggt gtacggcgtc agccacggtt
     4501 cacggccaaa gcgcgactgg aacgtcatca ttaccttttc cggcggcagt cccaatgcgg
     4561 aaaccagttc acgcgtggta tcgcgacagc gctgcgggta gtcatcgcct tcatccgcat
     4621 aacgttgtgg aatgccgtga taggagagca gaagtaaatc cggctcgccg tgtctggcga
     4681 acgactcacg cgcgcttttc gccagcgcat cgatataagc gccgtcatcc gcgtaatcgc
     4741 gaataaatga gatcccggga atacgacgtt tacgcgccag tatccgcccc agttcgtccc
     4801 agactgcgcc caccgttgag caagaatatt gcgggtacaa cggcagcacg acgatatggt
     4861 cgacgtcgct tgctaacagt tcatcgacag cgctttccag cgagggcgag ccgtagctca
     4921 tccccagcgc gacgggcgtg tctggcaacc gcgcggccag cgcctgttgc tgttcgcggc
     4981 tatataccat gagcggcgaa ccgccatcca tccagataga ttgatagagt ttcgcgacgc
     5041 gcggcgaacg cagcggtaaa ataacgccac gcagcagcgg ccaccacagc agacgaggag
     5101 tatccaccac gcgtctgtcg cttaaaaatt gtttcaggta gcgctttacc gcttcaggag
     5161 ttggggcatc tggcgtgcca aggttagcca gcaggatacc ggttttcgtc tgacgcattg
     5221 ccgcctctta tctattcaaa ttgttgataa ttgtagcgga aaagcgataa agaagaacta
     5281 attgctgcga gaggtaagac gagaatttgc cgaatggcgc taacgatacc ggtaggccgg
     5341 ataaggcgtt caggccgcca ttcggcaccg attgcctgat ggcgctacgc ttatcaggcc
     5401 tgcgggataa tggcaggcct gataagcggt tcactacgcg aaaaaaatta accgaggatt
     5461 ttttccagcg ctgcgcgcac gtcggcaacg gcctgcgtac cgtcaacttt agcgtatttg
     5521 gtgttgcccg cttccgcttc tttctggtag tagccaatca gcggcgcggt catctgatga
     5581 tattccacca gacgtttgcg aacggtctct tcctgatcgt ctttacgggt cgtcagatct
     5641 tcgccggtga cgtcatcttt gccttccact ttcggcggat taaacttaac gtggtaaacg
     5701 cggccagagg cggcgtgtac gcgacgaccc acaatacggt caacgatcag ttcgtccggt
     5761 acgtcgaatt ccagcacgta atccaccaca atacccgctt ctttcatcgc gtcagcctgc
     5821 gggatcgtgc gcgggaaacc gtccagcaga aaaccgttac ggcagtcttc ctgggcgata
     5881 cgctctttaa ccagcgcaat caccagttca tcggtcacca gtttaccggc gtccatgata
     5941 tctttcgcct gtttgcccaa ctcggagcct gatttcactg cggcgcgcag catatcgcca
     6001 gtggagattt gcggaatacc atatttctcc atgatgaact gagcctgagt tcctttaccc
     6061 gcgcccggag cgccaagcag aataatacgc attacgaaaa tcccctcaaa ggttgtcgat
     6121 attttttaaa aagcgctaaa cgataccacc atcacgcatt tcgctcaagg aagtcgcctg
     6181 atgctgaaac ggttaacgaa gagaaatcca gaaaagagaa ggtattataa aaaatgccgg
     6241 atggcgctgg cgcttatccg gcctacaaac agtactcgtc cgtaggccgg ataagatgct
     6301 tcgcgtcgcc atccggcagt cacaaaacag tactcgcccg taggccggat aagacgcttc
     6361 gcgtcgccat ccggcagtca caaaacagta cccgtccgta ggccggataa gatgcttcgc
     6421 gtcgccatcc ggcagtcaca aaacagtacc cgcccgtagg tcgggtaaga cgcttcgcgt
     6481 cgctatccgg caatcagatg agcgttatca ggacaccagc aactggttca tacggcggat
     6541 aaactggttc ggatcttcca gcgtaccgcg ttcagcgaac agcgcctgat ccagcagcag
     6601 ctcgacccac tctttaaact gcgcttcatc cttggtatcg gcagtgcgtt tgaccagcac
     6661 atgatccggg ttgagctcaa agatgtattt cacttccggc acggactgac cggccgcggc
     6721 gaacagtttc gccatctggg tgctcatttc atccgcatcg gtggtgacaa tcgccggcgt
     6781 gtcggttaaa cggtgtgtca gacgcacctc tttcacgcga tcgcccagca gggttttgac
     6841 acgctccacg aacggctcaa gcgccttttc cgcttctttc gcgttttcgt cgacttcatc
     6901 cgccagtttt tcgatggact catcggcttt agcgaccgac tggaatgctt taccgtcaaa
     6961 ctcggtcagg tagttcatca tccactcgtc gatgcgatcg gagagcagca gcacttcgat
     7021 gcctttctta cgcagcagct ccaggtgcgg gctgtttttc gccgccgcat agctgtctgc
     7081 ggtgatgtag tagatttttt cctgcccttc tttcatccgg gagacgtaat cttccagcga
     7141 cacggtctgg gcggaagagt cggtatgggt ggaggcaaag cgcaacagtt tagcgatcgc
     7201 ttcctggttg gcgtgatctt ccgccgggcc ttctttcaac accagaccga actgtttcca
     7261 gaaggtttgg tatttttccg cgtcgtcttt cgccagtttt tccagcattt gcagaacgcg
     7321 tttggtcagg gcgctgcgca gattacgcgt taccgtgctg tcctgcagga tttcacggga
     7381 gacattcaac ggcaggtcat tagaatcaat caggccgcgc acgaaacgca gatagttcgg
     7441 catgaactgc tcggcatcgt ccataatgaa cacacgctgt acgtacagct tcagaccatg
     7501 tttgtgatcg cggttccaca gatcccacgg cgcctgcgac gggatataca gcaggctggt
     7561 gtactcctgc ttaccttcca cgcggttgtg gctccaggtc agcggatcgg tgaaatcatg
     7621 cgcgatgtgc ttgtaaaact cgttgtactc gtcgtcttta atttccgact tgttacgggt
     7681 ccacaacgcc tgggccttgt tgattttctc ccaggaaatc acggtttcgc cgtctttttc
     7741 ttcccgtttt tcaatctcta ccggcaatgc gatgtgatcg gaatatttac tgataattga
     7801 gcgtacgcgc cagtcatcga ggaattcatc ttcgccttca cgcaggtgta aggtgatttc
     7861 cgtaccacgg tcatttttgg tgatatcggc aacggtatat tcgccttcgc ctgccgattc
     7921 ccagaacacg ccattttccg gcttgtcgcc tgccgcacgg gtacgtacgg tcactttatc
     7981 ggccacaata aacgcggagt agaagcctac gccaaactga ccgatgagct ggctatcttt
     8041 cgcctgatcg gaccccattg attcgaggaa agatttggtg ccggacttgg caatggtgcc
     8101 taagtggtca atcacctcat cacgattcat ccccacgccg ttatcggcaa tggtcaacgt
     8161 acgcttatct ttatcgaaag agacgcgcac acgcagctcg ccatctcctt catacaggtc
     8221 cgggtttgac agagcgcgga aacgcagctt gtccgccgca tctgaggcgt tagagatgag
     8281 ttcacgcagg aagatttctt tattggaata aagagaatgg atcatcaggt gcagaagctg
     8341 tttaacttct gactgaaaac cacgcgtttc ttgtcctttc atgtggatag acctcaacaa
     8401 tgccattttt aatggtaaaa atacgttgag ggtgagatgg ggacaagcgg gtgtgatttc
     8461 aagcggaggc cgcgaacgcc gcctccgttt gttcagaaaa taatcttatg gcgtcccgcc
     8521 agcgagtggg acagcgtcgt accgtcgacc atctccagtt cgccgccaac cggcacgccg
     8581 tgggcgatac gactggcttc gacgccggcc tccgcgcaca gctcggcaat atagttcgcg
     8641 gtagcctccc cttcaaccgt cgggttggtc gcgaggatca gctcgctgat tttttctgac
     8701 gccagccgct gttccagacg atcgagaccg atatcatccg gcccgatgcc gtccagcggc
     8761 gacaggtggc ccatcagcac gaaataccgc ccggaaaatt gcccggtctg ctcaatggcg
     8821 tagatatccg caggactctc caccacgcaa atctggccgt tttcctggcg ccgcgggttc
     8881 gaacagatat tacaaacatc ctgctcggta aaggtgcggc agtcggcgca gtggccgatt
     8941 tccgacatcg cccgggtcag cgcctgcgcc aggcgcattc cgccgctacg atcgcgctgc
     9001 aacagggtaa acgccatccg ttgcgccgac ttagggccga cgcccggaag gcagcgcaac
     9061 gcttccataa gctgagttaa cagcggactg gtttgcatca gaatggcatc ttaaagcctg
     9121 gcggcagttg cataccggaa gagacggaag ccatcttctc tttttgcgtc tcttcaatgc
     9181 ggcgcgccgc atcgttgaag gccgcagcga ccagatcttc cagcatctct ttgtcatctt
     9241 ccagcaggct tgggtcaatt tccacacggc ggcagttatg cgcaccgttg atggtaacct
     9301 tcaccagacc cgcgccggat tcgccggtca cttccagctg cgcaatctct tcctgcattt
     9361 tctgcatttt ttcctgcatc tgctgggcct gcttcatcag attgcccaga ccgccttttc
     9421 caaacataag ctctctctct tgatggttca caatcgcaag ccgggcttac gatcaaatgg
     9481 ggcggatact ctcttcatcc agctcggcgt cgaagaatcg acgcagcgtc tgaatgttat
     9541 tatccgcgat aattgactca cgcgcttgcg cgagtttctc ttcataaatg gcctgacgcc
     9601 attccagcgg cgtacgcacc gcgggattat catcttcaac gatggtcagt tcaaccgtcg
     9661 ttcccgtcag atcgctgagc gcttgcgcca gcttttgctg cgcaccgctg gaattgaggt
     9721 gccgctgcgt cgagcgcaga tgcagacaaa ccgcgttgcc gttctgctcc ttccaggcat
     9781 tgagcgccac ctgctccacc agcttaggca aagaaagctg gcttacctgc gccgcccacg
     9841 gatcgcgctc aatcgcttcc gccgccagtt tagccgccag ctccggcgtt ttttcatgct
     9901 ccagagcttt cttaagcgct tttggcgtag ccaccacttc tttggtttgc actaccggcg
     9961 tggtggcctt ccagcgataa gcctctttct ttactggcgt cgtttccagc gcagacggcg
    10021 ccgggcgcgc ctgtacgcgc tccgaaaccg aggccagccg ctccagcgca gagttattca
    10081 ccggccgcgc gcgggatgcg gctgccggtt cactcttttt tgttttggtt actccctgcg
    10141 cgcgctgtag ctgattgcgc gccgccagca cctgactggt agacgccggc agcggcgctg
    10201 gcgatgtctg cggcgcgggc gccgacggct gctgcacctg cggcggcgtc attaccgccg
    10261 ttggggccac gggcgcaaaa gactgccgcg gcgtttcagg ctccggcaag ggcatacgcg
    10321 ggtgaaacgc cagcgcacgc aataacgtca tttcaacgcc catccgccgg tccggcgccc
    10381 agggcaattc tttgcgacca atcaacaacg tctgataata gagctgaaga tcgccgggag
    10441 gcaccgtccg ggcaagttcg cgcatccgtt gctcgatagc cgccatatcg ctgcctaacg
    10501 cggcaggcga aagttgcacc atcgcaatac ggtgcagcag gctaagcatt tcgaccagca
    10561 gcgcttccca ttcaataccg cgcgccgccg cctcgttgat aagcgacatg acgcgttcgc
    10621 cgttagcgtc aaccactgcc tcgactaatg acaaagcctg gtcgtcgtcc agcgtaccga
    10681 gcatggcgct taccgcctgc gtcgaaacct gcccgtcgcc actggcgatc gcctggtcag
    10741 tcagacttaa tgcatcgcgc aggctgccgt cagccgcgcg tgataacaac tgcaacgcgc
    10801 ggggttcgtg agcgatatgt tcctcattga gaatatgctc aagctgatgg cgaatctgtt
    10861 caacatccag cgctttgaga tgaaactgta ggcagcgcga caaaatggtc accggcagct
    10921 tctgcggatc ggtggtcgcc agtaaaaatt tcacatgcgc tggcggctct tcaagcgttt
    10981 taagtagcgc attaaagctg tggcgcgaca gcatgtggac ttcatcgatc agatagactt
    11041 taaagcgacc gcgcgcaggc gcgtactgga cgttatccag caggtcgcgg gtgtcttcga
    11101 ctttggtacg cgatgcggcg tcaatctcaa tgagatcgac aaaacgccct tgctcaattt
    11161 cccgacagtt atcgcaaacg ccgcacggcg tcgcggtaat accggtttcg cagttcagcc
    11221 ccttcgccag cagtcgggcg atagaagttt taccgacgcc gcgcgtgccg gaaaaaagat
    11281 atgcgtgatg aatgcgccct aacgacaagc cgttcgccag tgcggtcagc acatgttcct
    11341 ggccgacgac gtcagcaaag gtttgtgggc gccattttct ggctaagacc tgataactca
    11401 ttggcaggct ctgaaacgct ggaaggtgga ttcatagaag ggtaatgcta acacaacctc
    11461 gccgatacag cgaggttgtc tctctggcta aaatagcagt gcgaatagcc tgaatcaatg
    11521 ccctggaaac ggcatcaggc tataacaggt aatcccctgc ttttccagac gctgctcgcc
    11581 gcccagatcg aacaaattga tgatgaacgc cgcatcggtg actttcccgc ccagacgacg
    11641 gatcagcttc acggtcgcct caatggtgcc gccagtcgcc agcagatcgt ccacgaccag
    11701 cacgttgtcg ccaggtttaa tcgcgtcgac atggatttcc agctgatcgg tgccgtactc
    11761 taattcatag gtctcggcaa tagtttcacg cggtaatttg cgcggtttac gtaccggaac
    11821 aaaaccaacg cccagcccaa gcgcaaccgg cgcgccaaac aggaagccac gcgcttcggt
    11881 gccgaccact ttggtgatac ccgcattttt ataacgctca actaacagtt caatactgag
    11941 cgcgtaggct ttcgggtctt ccagtaagct ggtgacatca cggaaaagaa tgcccggttt
    12001 cgggtaatcc tgaatgcttt tgatgctgtt tttgagaaac tcaagctgct gtgcagtcgc
    12061 ggtcatggat atatgcctgc taagtacggt gttactcacg gcgcaatact tttcagtcag
    12121 gggtaacgct cggttactct ttgaccgcct gcgcctgtgc tcgaaaacgg tcgaatttac
    12181 tggctgtgaa cgacaattgc aacagcgatt cgtgtgcttc agcgcttttg ttgcttttca
    12241 tcaatcaccg gtatccgcca cataaaaatc agcaggcagg ccaaaataac caacagcagc
    12301 acccgcaccc acatcatatt caccagccac agcgaaatac caaaggtcag caatatcaac
    12361 gcgatcgctc gcggtttcgc tcccggcggc atggcccgat agcgctgcca gtggcgcaga
    12421 taaccgccaa accatgagcg gtataacaac caagcatgga aacgcggcga cgagcgggcg
    12481 aaacaccagg ctgccagtaa aatgaacggc gtagtcggca acaggggcaa aaccacgccc
    12541 agtgtcccta atactaccgc cagccagcca atgatgatta aaatagtacg ttgcataatg
    12601 cgaatcgtta tcaaacagaa ggctactgta gcacagcctg tcttattttc atcggggtgt
    12661 tgaattgaaa accgctatgc tgttacagac gctggaagag aagctggcga cgctacgcca
    12721 acgctgcgcg ccgctggcgt aacatgcgac gttaagcgcg cgctttgacc gacacctttt
    12781 ccgtacccgc agtactctgt tgcagggata tctggaagag gcagacgcca atctcgccgc
    12841 gttgcgtcag gcggtaaaac atgagcaact gccgcaagtc gcctggctgg cggaacatct
    12901 ggcttcgcaa ctggaggcga tatcgcgtga aaccgccgcc tggtcgctgc gccagtggga
    12961 tgccgccgca ccagggcttg gccgttggca gcgcagacga atacagcatc aggagtttga
    13021 atgtcgactg ctggcgatga cacaggagcg caaaattcgt ctggcgcagg cgaccggcct
    13081 tgtcgaacaa caaacgctgc aaaaggaagt cgagatctat gaaggacggc tggcgcgctg
    13141 ccgacatgcg ctggagaaaa tagaaaacgt actggcgcgt ttaccccgtt aacccaggag
    13201 aaagtatgtc gcttgaaaat gcccctgatg aagtcaaact ggccgtggat ttaattgtgc
    13261 tgcttgaaga gaatcgctta ccggcacgaa cggtgctacg cgcgctggaa atagttatgc
    13321 gtgattatga aaacaagtta aaaagtacgg aagacgactc gcaaacagag taatagcccc
    13381 ctggtttgtc ctcgttgtcg ctgacaaagt ggtcgctaca gtcaggcaac aaaggacggg
    13441 gcatggaacg tctacccacc acgccgcacg atgcggtatt ccgacagatg ctgatgcaaa
    13501 aagaggtcgc ccgcgacttt ctggctatcc acttgccaga agactttctt gcaatctgcg
    13561 atctggattc actgaagctg gagtcgggga gttttgttga agacaattta cgcagccgct
    13621 attcagatat tctctactct ctgcataccc aacacggccc cgggtatgtt tacgcgctta
    13681 ttgaacatca gagcaaatca gaccggctga tggcttttcg cctgatgcgg tacgccattg
    13741 ccgccatgca gcgtcatctg gatgccggcc atgatacctt gccgctggtg gtaccaatcc
    13801 tcttttatca cggtccggaa agcccgtggc cctatagcct taactggcat aatatgtttg
    13861 tgaaaccgga tatggcgaaa gccttataca gtcatgaatt tgcgctggtc gacctaacga
    13921 taatgccgga taatcagctt ttgcagcatc ggcggatagc gatgttagag ctcctgcaaa
    13981 aacatattcg tcaacgcgat ttaagcgaac tgctcgaccc ccttatcacg cttttaacgc
    14041 aggatcattt gacggacgcg cagctcagtg tgctgatcaa ctatatgttg aaagcaggaa
    14101 acgccgcaga acccggggcg ctaattcgtc aactggcgca gggcgcgccg cagtataagg
    14161 aacaactgat gacaatagcg gaatggctgg aagaaaaagg ccgaacggaa gggttgcgaa
    14221 aagggcttga gcaagggttg gcacaaggcc gtgaggccga agcgcgcgct attgcccgca
    14281 aaatgcttgc caacgggctg gaacccgggc tcatcgccag cgtcaccggc attacgccgg
    14341 aagagctttc tacgctttcg cattagcggc gccgcgcgca ctcataaagc gcgcggccca
    14401 ccgcctttta gcttgccgcc ggcgccagat cgccgccgtt gagatcgcgc ttcacttcag
    14461 tgacttcgtc gcccttcgcg ttatgcagat gcacctcaag ctggttaaag gcaatattga
    14521 tatcattttc acggcacagt cgatcgatcg cgcggttcag ttcatccacc gtatggctac
    14581 gatcacgcaa ttcacgcaca tacagacgca gttcatgatc cagagtgctg gcgccaaagg
    14641 tggtgaagaa tacggcaggt tccggatcgt gcatcacctt cggatgctcc atcgccgcct
    14701 gtagcaggac tcttttcact ttctccagat ccgagccata ggccacgcca agccggatca
    14761 ccagacgtgt cgtggtatcg gagagggacc agttaatcag ccgctccgtt acgaacgctt
    14821 tgttcggaat gatcacttct ttacgatcaa aatcggtaat agtggtggcg cgaatacgaa
    14881 tcttactgac cgtgccggag taggtgccga tcgttaccgt atcgccaatg cgtaccggac
    14941 gttcgaagag gatgattaaa cccgagacaa agttaccgaa gatctcctgt agcccaaaac
    15001 cgagacctac cgacaacgcc gccgccagcc actggagttt atcccacgag acgccgagcg
    15061 atccgaatac tgtcatcgcg ccaacagcga taatgacgta gttaaggatc gtggtgatcg
    15121 catacgaagc cccttggcgc atattcaggc gtgaaagcac cagcacttcc agcaggccgg
    15181 gtaagttgcg gatgagcgcc caggccacca tcgcggcaat aatggcaaat agcaagctgc
    15241 ccatcgtcac gcttttcacc accgcagcgc cagcttcgga gccgttgtag tgccacagcg
    15301 tgatgctatc aagatagctg aatacggtga tcaaatcgga ccaaatcgcc cagaacataa
    15361 cgccaaacag ggcaagcatt agcagcatcg tgatacgtaa tgtttgctgg ttaatttgct
    15421 ccaacgcgat ggtgggttct tcctgtggtt ccgccccttc cgctccctct tttaccaggt
    15481 tctgacgacg agccagcgcg cgtcgccagg caatccggcg cgccgctaca cttaacccgc
    15541 gcagcaccgt ttgataaagc aggttccaga taatgaccag atagacggtt tcaatccagc
    15601 gccccgccag gcgcagggtg gtatagaaat agccagtcgc cgttaatacc attaacgcca
    15661 ctggaataat ggaaagaatc gtcacggtca ccagtcgaat gccgtgagat tctttatcgc
    15721 gccagctttc ccggcacagt ggccacacca gcaatgttat gaccagcaga ttgaggaaaa
    15781 taaccgcctg ccccagcacg tcatccatca gattcagcgg cgacaactcc gccaccacag
    15841 accaaaagtg cagcggcagc aatgcgaggc taatgcgtac aatctggcga cgccagtggc
    15901 tggtcaactg cgccggcata ccaaaatggc gtatcgccac gccttctttt tccagcacct
    15961 tccagcacag cccaaagacc agccagaaca tcgcgagctt tttactaaag gcccagagca
    16021 gatcgctgat atttagctgc atggtcagca ggatcaatcc aatcgcgagg ataatcaggc
    16081 acaccggcag cgcgcggatc agatcgatca gaatagcttt tggcgtattg agctgactat
    16141 cgttacgcag cgatcccacg gcggcggcca gcttctgttg atacgctttt aaccatttca
    16201 gacgccagcg gattaaaccg gcgatgagca agagcggcaa cccggccaaa aaagcaataa
    16261 atactgcggg ccaggctttt tgccagttca ccgtgatttt catggcgctg aattgctctt
    16321 ttaacgtttg ggggaacgct ttaagccagt cccagtccat agggcggtta ctgttcaccc
    16381 aaaaaatctg ctgcgtcaga atggctttca gatttttcga gacgctcatc aactgctgct
    16441 ggttaacttg caggttaatc gccatcatca gctggttacc caactgttta tttagctgat
    16501 ccaatagctc acggcgcatc tccaccacct gaagcaacgc atcatgaact tcatcattca
    16561 cctcgctggt atgcccctcc tccagcttgt cgacaaaggc atcgctttgg aataaggcat
    16621 cacgctgctg gttgatttca aactgctcca gacgcaaatc cgcaatgcgg ttggtcatat
    16681 cttcgagttc gtcggcggag ggcagggttt gctgctgttg ataaagaata cgcgacagca
    16741 acaggctgcc ttttaagacg gcaatctgtt ctttgatatt tctttccgac tgcagagcgc
    16801 gatcgagcca gttttttact ttaatgtttt gctgcatcaa catattgccg ttttcggtcg
    16861 cgacaatcag acgctggctg agttgatggt taatatccag ttcctgtttt accaacgggt
    16921 tcgcctggat acgcgccgtt tcgtccggcg aaatagcctc ctgggccgtt ttttccgtta
    16981 gcgtaagtcg tttactgttg accgcctcct gtaaaagttg aagctgatgt tcaaggcgat
    17041 tactgttggc cgtcacgtaa tcccgctgtt tttgcagggt gtcctgcaaa acggtattcc
    17101 cttcaagact cttacgttgc tggtcgatct gcgcattaag cagcgcctgt tgtgcctgta
    17161 ataacacctg ttggctgggg cgaagcgcgg cttcgccgac gttattgccg tccagacggt
    17221 tacggatttg ctgtatttgc tgtgaggcgg tatacatggc gttttgcacg cgctccggct
    17281 gggtttgtag cgaaacaagc tggctgttat aagcggcaag atcgttttgc gagttttgca
    17341 aatcatccag tacctgcgcc acgcgcagct caagctgacg tagcgaaagc gcactcagcg
    17401 tttttcgcat ttcatcatca ttatcgacat cgctcagcgc attcaacgca gccgtcgcct
    17461 gacgcatttt ttcaggcgcc tgcgccacct tctgccgtag ctgtacggtc tcctctttta
    17521 cccgctcgat tttctccagc gtagctaacg tatcaataag gtcttgctgg acgagcttat
    17581 cctgggcgga gagatctttt tgcttattca gcgtatccag ctggttttgc acatccgctt
    17641 ttgacggcag gtcgccattc gtttgccccc gggcaaacgc cagagactga caggacagca
    17701 ggataataag aacgctaatt gtaataaaaa caaaatgctg tgaacgttta taaagctgca
    17761 acatagtcat gagaatgaag tgtctgaacc ggcaagcaga ccggaaataa ttgagtcgca
    17821 agaatatcac gcctgtaaca aacagaatag cgacacagaa aatgtccagg agttttcctg
    17881 gaatattatc agggggagcc gttgaccgtc gacgcgcgca gcgtcggaca caattgatac
    17941 atctccagca ggatcgtgac gtaggcgcga gcttcttttt ttaaatcaaa cgattgcgga
    18001 gcaaataacc agttttccat gagccctgaa ataaagctgc gcatcagtat cgccgcacga
    18061 cgggtcagca gattttcagg cagcatttta gcattaatac aatgttttaa cgtttgttca
    18121 atccgatcgt aactttccag acaaaggcta cgttgcgcct gttgaaccac aaccatttct
    18181 ccgacaaact cacatttatg gaatataatc tccatcaata agcggcgtcg ttcttctgtt
    18241 acagtagctt caagaatatg aactaaaatt tctcttaata cagatagtgg atcgtcgggg
    18301 aattttgcct gatactcaat ctcaagctca ccaatattgg attctgatag ctcccagatc
    18361 tcactgaata aatccgactt atttttgaaa tgccaataga ttgcgccgcg cgtcacgcca
    18421 gcagcgttcg caatctccgc cagcgaggtt gccgatacgc cttgctgcga gaacaaacgc
    18481 agggccacat ccaggatgtg ttgtcgtgtc tccagcgctt gttgtttggt ttttcgtgcc
    18541 atatgtcggt gaatttacag gcgttagatt tacatacatt tatggatgta tgtaccatag
    18601 catgacgata atataaacgc agcaatgggt ttaaggacct ttgaccattg accaatttga
    18661 aatcggacac tcgaggttta catatgaaca aaaacagagg gttaacgcct ctggcggtcg
    18721 ttctgatgct ctcaggcagc ttagcgctaa caggatgtga cgacaaacag gaccagcaag
    18781 gcggccagca gatgccagaa gttggggttg tcacactaaa aacggaacca ctgcaaatca
    18841 caactgaact tccgggtcgt accgttgctt accgtatcgc cgaagttcgc ccgcaggtaa
    18901 gcggcattat cctgaagcgt aatttcgttg agggaagtga tatcgaagcg ggagtctctc
    18961 tctatcagat tgatcctgcg acttaccagg cgacttacga cagcgctaag ggcgatctgg
    19021 caaaagcgca ggccgccgcg aatatcgctg aactgacggt gaagcgttat caaaagctgc
    19081 tgggtacgca gtacatcagt aagcaggaat acgatcaggc gctggctgac gcgcaacaag
    19141 cgactgccgc cgttgtcgca gcaaaagccg ccgttgaaac cgcacgtatc aacctggcgt
    19201 ataccaaagt cacctcaccg attagcggtc gtattggtaa gtcgtccgta acggaaggcg
    19261 cgctggtaca gaacggtcag gcgtcggcgc tggcgacagt gcagcagctg gaccctattt
    19321 atgtcgatgt gacccagtcc agcaatgact tcctgcgcct gaagcaggag ctggcaaatg
    19381 gttcgctgaa gcaggaaaac ggcaaagcga aggtcgatct ggtgacaagc gacggtatca
    19441 aattcccgca gtccggtacg cttgaattct ccgacgtgac cgttgaccaa agcaccgggt
    19501 ctattacttt gcgcgccatc ttccctaacc cggatcacac cttattgcca ggaatgttcg
    19561 ttcgcgcacg tctgcaggaa gggacaaaac cgacggcatt actggttcca caacagggcg
    19621 ttacccgtac tccacgcggc gatgccacgg tgctggtggt tggcgctgat aacaaagtgg
    19681 aaacccgcca aatcgtcgca agccaggcga tcggcgataa gtggctggtg actgacgggt
    19741 tgaaagcggg cgaccgcgta gtcgtcagcg ggctgcaaaa agtacgtcct ggcgcacagg
    19801 ttaaagtgca ggaaattacc gcggataaca aacagcaagc cgcaagcggt gatcaacctg
    19861 ctcagcccag gtcttaactt aaacaggagc cgttaagaca tgcctaattt ctttatcgat
    19921 cgccctatat ttgcgtgggt gatcgccatc atcatcatgt tggcaggggg gctcgcgatc
    19981 ctcaaattgc cggtagcgca atatccgacg attgcgccac cagcagtgac gatctccgca
    20041 acctaccctg gcgctgatgc gaaaacggta caggataccg tcacgcaggt tatcgaacag
    20101 aatatgaacg gtatcgataa cctgatgtat atgtcctcca acagtgactc cacggggacc
    20161 gtacagatca cgctgacctt tgaatccggc accgatgcgg atatcgcgca ggttcaggtt
    20221 cagaacaagt tgcaactggc aatgccgtta cttccccagg aagtacagca acagggcgtg
    20281 agcgttgaga agtcctcaag tagcttcctg atggtagtgg gcgtcattaa caccgacggc
    20341 accatgaccc aggaggatat ttcggattac gttgccgcca atatgaaaga tccgatcagc
    20401 cgtacctctg gggtgggcga cgtccagctg tttggttcgc agtatgcgat gcgtatctgg
    20461 atgaatccga cagagctgac caaataccaa ctgacgccgg tcgacgtgat taacgcgatc
    20521 aaagcgcaga acgcccaggt cgcggcaggt cagctcggtg gtacaccgcc ggtaaaaggc
    20581 cagcagctta acgcatcgat tattgcccaa acgcgtctga cctcaacgga tgagtttggc
    20641 aaaatcctgc tgaaagtgaa tcaggatggc tctcaggttc gtctgcggga tgtagcgaaa
    20701 attgagcttg gcggcgaaaa ctacgacgtc atcgcgaaat ttaacggtca gccagcgtca
    20761 ggtcttggca tcaaactggc taccggcgcc aacgcgctgg ataccgctac cgctattcgc
    20821 gccgaactga aaaaaatgga accgttcttc ccgccaggga tgaaaatcgt ctacccgtat
    20881 gacaccacgc cgttcgtgaa gatctctatt catgaagtgg taaaaacgct ggtcgaagcg
    20941 attatcctcg tgttcttggt gatgtacctg ttcctgcaga acttccgcgc gacgttgatt
    21001 ccgactattg cggttccggt ggtgttgttg ggaacctttg ccgtgcttgc ggcattcggt
    21061 ttctcgataa acacgctgac gatgttcggg atggtgctcg ccatcggctt gctggtggat
    21121 gacgccatcg tggtggtcga gaacgtcgaa cgtgttatga cggaagaagg ccttccgccg
    21181 aaggaagcga cgcgcaaatc catgggccag attcagggcg cattggtggg tatcgcgatg
    21241 gtactgtcgg cggtatttat tccgatggcc ttctttggcg gctcaaccgg ggcaatttat
    21301 cgtcagttct ctatcaccat cgtatcggcg atggcgctgt cggtgctggt cgcgctgatc
    21361 ctgacgcccg cgctgtgcgc gacgatgctc aaacccgtcg ccaaaggcga tcatggcgaa
    21421 gggaaaaaag gctttttcgg ctggtttaac cgcctgtttg ataagagcac gcatcactac
    21481 accgatagcg tagggaatat tctgcgcagc accgggcgtt atctgctgct ctatctcatt
    21541 atcgtcgtcg gtatggctta tctgttcgtt cgtctgccaa gctctttctt gccggatgaa
    21601 gaccagggcg tattcctgac aatggtccag ctccccgccg gcgcgacgca agagcgcacg
    21661 caaaaagtgc tggatgaggt cacggattac tatctgaaca aagagaaagc caacgttgaa
    21721 tcggtattcg ccgtcaacgg cttcggtttt gcagggcgcg gtcagaatac cggtattgca
    21781 tttgtgtcgt tgaaagactg ggccgatcgt ccaggcgaaa aaaacaaggt tgaagcgatt
    21841 acccagcggg caaccgcagc gttttcacaa attaaagatg cgatggtctt cgcctttaac
    21901 ctaccggcga ttgttgaact gggcaccgca accgggtttg acttcgagtt gattgaccag
    21961 gcgggacttg gtcacgaaaa actcacccag gcacgtaatc agttgttcgg cgaggtggcg
    22021 aaatatcctg atctgttggt cggcgttcga cctaacggtc tggaagatac gccgcagttt
    22081 aaaatcgata tcgaccagga aaaagctcag gcgctgggcg tgtctattag cgacattaat
    22141 accacgctgg gcgcagcatg gggcggcagc tatgtaaacg actttatcga tcgcggtcgt
    22201 gtgaagaaag tttacgtgat gtccgaagcg aaataccgca tgttgccgga tgatattaac
    22261 gactggtacg ttcgtggtag cgatggtcag atggtgccgt tctccgcatt ctcctcttcc
    22321 cgctgggaat atggttcgcc gcgtctggaa cgctataacg gtctgccttc gatggaaatt
    22381 ctgggtcagg cggcgccagg caagagtact ggtgaagcga tggcgatgat ggaagaactg
    22441 gccagcaagc tgccgtcagg cattgggtat gactggaccg ggatgtccta ccaggagcgg
    22501 ttgtccggca accaggcccc tgccctgtat gctatctcgc taatcgtcgt cttcctgtgt
    22561 ctggcggcat tgtatgagag ctggtctatc ccgttctccg taatgctggt tgttccgctt
    22621 ggggttatcg gcgcgctgct ggccgcgacc ttccgcggac tgactaacga cgtttacttc
    22681 caggtgggcc tgctcacaac cattgggttg tcggcgaaga acgcgatact tatcgtcgaa
    22741 ttcgccaaag acttaatgga taaagaaggg aaaggtctgg tagaagcgat gctggaggcc
    22801 gtccggatgc gtttgcgtcc gattctgatg acctcgttag cgttcatgct gggggttatg
    22861 ccgctggtta tcagttccgg cgcgggttcc ggcgcgcaga atgcggtagg tactggcgta
    22921 ctgggcggga tggtaacggc aaccgtactg gctattttct tcgtaccagt cttcttcgtg
    22981 gtggtacgcc gccgctttag ccgtaaaagc gaagatattg agcatagtca ttcgacagaa
    23041 catcgctgat ttgctcactg ttgataa
//
LOCUS       DAJVBX010000056        22924 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.056, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000056 DAJVBX010000000
VERSION     DAJVBX010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 22924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22924
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.056"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            12..272
                     /locus_tag="OPV72_001875"
     CDS             12..272
                     /locus_tag="OPV72_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HCR9914193.1"
                     /translation="MKTIKYAVAAIALSTLSFGAFAAEPVSASQTQNLHKIGVVSADG
                     ATTLDGLEAKLAEKAAAAGASAYNITSAVGNDKMSGTAVIYK"
     gene            complement(428..1402)
                     /gene="ybiB"
                     /locus_tag="OPV72_001876"
                     /pseudo
     CDS             complement(428..1402)
                     /gene="ybiB"
                     /locus_tag="OPV72_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459800.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein YbiB"
     gene            complement(1432..3576)
                     /gene="dinG"
                     /locus_tag="OPV72_001877"
                     /pseudo
     CDS             complement(1432..3576)
                     /gene="dinG"
                     /locus_tag="OPV72_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459799.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase DinG"
     gene            complement(3784..5142)
                     /gene="rhlE"
                     /locus_tag="OPV72_001878"
     CDS             complement(3784..5142)
                     /gene="rhlE"
                     /locus_tag="OPV72_001878"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase RhlE"
                     /protein_id="HCR9914194.1"
                     /translation="MSFDSLGLNPDILRAIAEQGYREPTPIQQQAIPAVLEGRDLMAS
                     AQTGTGKTAGFTLPLLQHLITHQPHAKGRRPVRALILTPTRELAAQIGENVRDYSKYL
                     NIRSLVVFGGVSINPQMMKLRGGVDVLVATPGRLLDLEHQNAVKLDQIEILVLDEADR
                     MLDMGFIHDIRRVLAKLPAKRQNLLFSATFSDDIKALAEKLLRNPLEIEVARRNTASE
                     QVTQHVHFVDKKRKRELLSQMIGQGNWQQVLVFTRTKHGANHLAEQLNKDGIRSAAIH
                     GNKSQGARTRALADFKSGDIRVLVATDIAARGLDIEELPHVVNYELPNVPEDYVHRIG
                     RTGRAAATGEALSLVCVDEHKLLRDIEKLLKKEIPRITTPGYEPDPSIKAEPIQNGRQ
                     QRGGGRGRGQNQGGAGRSQQPRRQDSGAAKAKPKPRTGEGKPAGDKARPPRRPRRITP
                     AQ"
     gene            5372..6046
                     /gene="cecR"
                     /locus_tag="OPV72_001879"
     CDS             5372..6046
                     /gene="cecR"
                     /locus_tag="OPV72_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator CecR"
                     /protein_id="HCR9914195.1"
                     /translation="MNIPTTTTKGEQAKSQLIAAALAQFGEYGLHATTRDIAALAGQN
                     IAAITYYFGSKEDLYLACAQWIADFLGEKFRPHAEKAERLFSQPAPDRDAIRELILLA
                     CKNMIMLLTQEDTVNLSKFISREQLSPTSAYQLVHEQVIDPLHTYLTRLVAAYTGCDA
                     NDTRMILHTHALLGEVLAFRLGKETILLRTGWPQFDEEKAELIYQTVTCHIDLILHGL
                     TQRSLD"
     gene            6046..7041
                     /gene="hlyD"
                     /locus_tag="OPV72_001880"
     CDS             6046..7041
                     /gene="hlyD"
                     /locus_tag="OPV72_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="secretion protein HlyD"
                     /protein_id="HCR9914196.1"
                     /translation="MKKPVVIGLVIAAIVAVIAGGTWWYQSRQDDGLTLYGNVDIRTV
                     NISFRVGGRLASLNVDEGDTIKAGQVLGELDHAPYENALMQAKAGVSVAQAQYDLMLA
                     GYRDEEIAQAAAAVRQAQAAYDYAQNFYNRQQGLWKSRTISANDLENARSSRDQAQAT
                     LKSAQDKLSQYRTGNREQDIAQAKASLEQAKAQLAQAQLDLQDTTLIAPANGTLLTRA
                     VEPGSMLNAGSTVLTLSLTRPVWVRAYVDERNLSQTQPGRDILLYTDGRPDKPYHGKI
                     GFVSPTAEFTPKTVETPDLRTDLVYRLRIIVTDADDALRQGMPVTVKFNDEARHE"
     gene            7034..8770
                     /locus_tag="OPV72_001881"
     CDS             7034..8770
                     /locus_tag="OPV72_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR9914197.1"
                     /translation="MSEAVITLNGLTKRFAGMDKPAVAPLDCTIHSGYVTGLVGPDGA
                     GKTTLMRMLAGQLKADGGSASVLGFDPIQNDSELHAVLGYMPQKFGLYEDLTVMENLN
                     LYADLRSVTGEIREKTFARLLEFTALGPFTGRLAGKLSGGMKQKLGLACTLVGEPKVL
                     LLDEPGVGVDPISRRELWQMVHELAGDGMLILWSTSYLDEAEQCRDVLLMNEGELLYQ
                     GEPKALTQTMAGRSFLMSSPQENNRKLLQRALRLPQVSDGMIQGRSVRLILKKEATAA
                     DIRQAEGMPEITLNETAPRFEDAFIDLLGGAGTSESPLGSILHTVEGTAGETVIEAQE
                     LTKKFGDFAATDHVNFVVQRGEIFGLLGPNGAGKSTTFKMMCGLLVPTSGKALVLDMD
                     LKVSSGKARQHLGYMAQKFSLYGNLTVEQNLRFFSGVYGLRGRAQNEKIQRMSEAFGL
                     KSIASHPTDALPLGFKQRLALACSLMHEPDILFLDEPTSGVDPLTRREFWLHINSMVE
                     KGVTVMVTTHFMDEAEYCDRIGLVYRGKLIASGTPDDLKAQAADEQQADPTMEQAFIT
                     LINDWDKEHTHE"
     gene            8763..9893
                     /locus_tag="OPV72_001882"
     CDS             8763..9893
                     /locus_tag="OPV72_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR9914198.1"
                     /translation="MSKSLSWRRVRALCVKETRQIVRDPSSWLIAVVIPLLLLFIFGY
                     GINLDSSKLRVGILLEQQSQEALDFTHAMTGSPYIDATISDNRHELIEKMQAGRIRGL
                     VVIPVDFAQQMARDGDSAPIQVITDGSEPNTANFVQGYVEGIWQIWQQQRAEDRGDTF
                     EPLIDVQTRYWFNPAAISQHFIIPGAVTIIMTVIGAILTSLVVAREWERGTMEALLST
                     EVTRVELLLCKLIPYYFLGMLAMLLCMLVSVFILGVPYRGSLVILFIITSLFLLSTLG
                     MGLLISTITRNQFNAAQVALNAAFLPSIMLSGFIFQIDSMPAVIRAVTYIIPARYFVS
                     TLQSLFLAGNIPVVLGVNVLFLIASAVMFIGLTWLKTKRRLD"
     gene            10009..11115
                     /locus_tag="OPV72_001883"
     CDS             10009..11115
                     /locus_tag="OPV72_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR9914199.1"
                     /translation="MFHRLWTLIRKELQSLLREPQTRAILILPVLIQVILFPFAATLE
                     VTNATIAIYNEDNGKHSVELTQRFARAKAFTHVLLLNSPQEIQPTIDTQKALLLVRFP
                     ADFSRNLDTFQPAPMQLILDGRNSNSAQIAANYLQQIVKEYQQTLMDGKPKPNNSELV
                     VRNWYNPNLDYKWFVVPSLIAMITTIGVMIVTSLSVAREREQGTLDQLLVSPLTTWQI
                     FVGKAVPALIVATFQATIVLAIGIWAYQIPFAGSLALFYFTMVIYGLSLVGFGLLISA
                     LCATQQQAFIGVFVFMMPAILLSGYVSPVENMPVWLQNLTWINPIRHFTDITKQIYLK
                     DASLGIVWGSLWPLLVIAATTGSAAYAMFRRKVM"
     gene            complement(11077..11487)
                     /locus_tag="OPV72_001884"
     CDS             complement(11077..11487)
                     /locus_tag="OPV72_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhQ family protein"
                     /protein_id="HCR9914200.1"
                     /translation="MKWQQRVRVATGLGCWQIMLHLLVVAMLVIGWMSGTLVRVGLGL
                     CVLYGVTVLLMLALQRHHEQRWRDVADVLEELTTTWYFGTALIVLWLLSRVLQNNVLL
                     ALAGLAILAGPAVVSLLAKDKKLHHFASKHRIRR"
     gene            11620..12378
                     /locus_tag="OPV72_001885"
     CDS             11620..12378
                     /locus_tag="OPV72_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HCR9914201.1"
                     /translation="MTQHTRNFSFKVLTINTHKGFTAFNKRFILPELRDAVRTVGADI
                     VCLQEVMGAHEVHPLHIENWPDTTHYEFLADTMWSDFAYGRNAVYPEGHHGNAVLSRY
                     PIEHYENRGVSVGGSEKRGVLYCRITPPMLNRPIHVMCVHLGLRESHRQAQLTMLAGW
                     VNALPESEPVLVAGDFNDWRQKAGPPLNAAGLEEIFTRAHGRPARTFPVSMPLLRLDR
                     IYVKNANASSPGALPLRNWRHLSDHAPLSAEIHL"
     gene            12375..13616
                     /gene="clsB"
                     /locus_tag="OPV72_001886"
     CDS             12375..13616
                     /gene="clsB"
                     /locus_tag="OPV72_001886"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase ClsB"
                     /protein_id="HCR9914202.1"
                     /translation="MKCGWREGNQIQLLENGDQFYPAVFEAIAQAQQKIILETFILFE
                     DEVGKKLHAALLKAAQRGVKAEVLLDGYGSPDLSDAFVGELTSAGVIFRYYDPRPRLL
                     GLRTNIFRRMHRKIVVIDDRIAFVGGINYSAEHMSDYGPQAKQDYAVRVEGPVVADIL
                     QFEVENLPGQSPARRWWKRHHQAEENRHPGEAQALFVWRDNEEHRDDIERHYLKMLTQ
                     AKREVIIANAYFFPGYRLLHAMRKAARRGVSVKLIVQGEPDMPIVKVGARLLYNYLVK
                     GGVQVYEYRRRPLHGKVALMDDHWATVGSSNLDPLSLSLNLEANLIIHDRTFNQTLRD
                     NLQGIIVNDCKQVDESMLPKRTWWNLTKSVLAFHFLRHFPALVGWLPAHTPHLAQVPP
                     PAQPEMETQDRVDPENSGVKP"
     gene            13616..14578
                     /locus_tag="OPV72_001887"
     CDS             13616..14578
                     /locus_tag="OPV72_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0104 family protein"
                     /protein_id="HCR9914203.1"
                     /translation="MAKSHPRWRLAKKVLTWLFFIAVVVLLVVYAKKVDWGDVWTVIR
                     DYNRTALLSAVGLVIVSYLLYGCYDLLGRLYCGHKLAKRQVMLVSFVCYAFNLTLSTW
                     VGGIGMRYRLYSRLGLPGSTITRIFSLSITTNWLGYILLGGIIFTFGVVQLPDHWYID
                     EGTLRILGIVLLLIIAVYLWFCAFAKRRHMTIKGQKLVLPSWKFALAQMAISSANWMA
                     MGAIIWLLMGQDVNYFFVLGVLLVSSIAGVIVHIPAGIGVLEAVFLALLAGEHTSQGT
                     IIAALLAYRVLYYFIPLLLALVCYLILESRAKKLRAKNERAMAK"
     gene            complement(14581..14823)
                     /locus_tag="OPV72_001888"
     CDS             complement(14581..14823)
                     /locus_tag="OPV72_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914204.1"
                     /translation="MSGVIIYRYVLLLAIISVTLATFCTLSSVFMGEFNEVLLLLFSW
                     SLLLFSRLQMNTSFFSAYVYFYRIKRVVLESENASA"
     gene            complement(15013..15720)
                     /locus_tag="OPV72_001889"
     CDS             complement(15013..15720)
                     /locus_tag="OPV72_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HCR9914205.1"
                     /translation="MGPLAAIRIRQIAFIPATMLSLTYWYTALGLWCTAGIIWLTLYS
                     HFLITHVQPVVVLWISALLLGLGYGAVTCLSRFGTVVATLIYIAIITLTGVSLAYLFS
                     GGATIFVIVGIMFSLNALFIFYLNISSGLFRPLIFMAVSGIIAAIVVNSLVASSTLVW
                     IVSVLTVLVWTLITALEKSTLHGYARMLYHSEFSSLPRCALFGALTLYLGIINAVVTL
                     CRYIILMILEILLSFRP"
     gene            complement(15867..16572)
                     /locus_tag="OPV72_001890"
                     /pseudo
     CDS             complement(15867..16572)
                     /locus_tag="OPV72_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459785.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
     gene            complement(16620..17072)
                     /gene="moaE"
                     /locus_tag="OPV72_001891"
     CDS             complement(16620..17072)
                     /gene="moaE"
                     /locus_tag="OPV72_001891"
                     /EC_number="2.8.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin synthase catalytic subunit MoaE"
                     /protein_id="HCR9914206.1"
                     /translation="MHETRIVVGPAPFSVGEEYSWLAARDEDGAVVTFTGKVRNHNLG
                     DSVKALTLEHYPGMTEKALAEIVAKARSRWPLGRVTVIHRVGELWPGDEIVFVGVTSA
                     HRSSAFDAGQFIMDYLKTRAPFWKREATPEGDRWVEARDSDQQLAKRW"
     gene            complement(17074..17319)
                     /gene="moaD"
                     /locus_tag="OPV72_001892"
     CDS             complement(17074..17319)
                     /gene="moaD"
                     /locus_tag="OPV72_001892"
                     /EC_number="2.8.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin synthase sulfur carrier subunit"
                     /protein_id="HCR9914207.1"
                     /translation="MIKVLFFAHVRELTGTDALDLPADFSTVESLRQHLATKSDRWAL
                     ALEDGKLLAAVNQTLVSFDHPLTAGDEVAFFPPVTGG"
     gene            complement(17312..17797)
                     /gene="moaC"
                     /locus_tag="OPV72_001893"
     CDS             complement(17312..17797)
                     /gene="moaC"
                     /locus_tag="OPV72_001893"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HCR9914208.1"
                     /translation="MSQLTHINAAGEAHMVDVSAKAETVREARAEAFVTMRSETLAMI
                     VDGKHHKGDVFATARIAGIQAAKRTWELIPLCHPLLLSKVEIQLQAEPEHNRVRIESL
                     CRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDIVIGPVRLLAKSGGKSGDFKVDAH
                     D"
     gene            complement(17800..18312)
                     /gene="moaB"
                     /locus_tag="OPV72_001894"
     CDS             complement(17800..18312)
                     /gene="moaB"
                     /locus_tag="OPV72_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor biosynthesis protein B"
                     /protein_id="HCR9914209.1"
                     /translation="MSQVSAEFIPTRIAILTVSSRRGEEDDTSGHYLRDSAQEAGHEV
                     VAKAIVKENRYAIRAQVSAWIASDEVQVVLITGGTGLTEGDQAPEALLPLFDREVEGF
                     GEVFRMLSFEEIGTATLQSRAVAGVANNTLIFAMPGSTKACRTAWENIIAPQLDARTR
                     PCNFHPHLKK"
     gene            complement(18334..19323)
                     /gene="moaA"
                     /locus_tag="OPV72_001895"
     CDS             complement(18334..19323)
                     /gene="moaA"
                     /locus_tag="OPV72_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HCR9914210.1"
                     /translation="MASQLTDAFARKFYYLRLSITDVCNFRCTYCLPDGYKPGGVTNN
                     GFLTVDEIRRVTRAFASLGTEKVRLTGGEPSLRRDFTDIIAAVGENDAIRQIAVTTNG
                     YRLARDAANWREAGLTGVNVSVDSLDARQFHAITGQDKFRQVMAGIDAAFDAGFEKVK
                     VNTVLMRDVNHHQLDTFLAWIQPRPIQLRFIELMETGEGSDLFRKHHISGQVLRDELI
                     KRGWIHQLRQRSDGPAQVFCHPDYAGEIGLIMPYEKDFCATCNRLRVSSVGKLHLCLF
                     GDGGVSLRDLLQDDAQQYALEERISDALREKKQTHFLHQSNTGITQNLSYIGG"
     regulatory      complement(19311..19455)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01055"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="molybdenum cofactor riboswitch; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="molybdenum cofactor"
                     /db_xref="RFAM:RF01055"
     gene            19720..20628
                     /gene="yvcK"
                     /locus_tag="OPV72_001896"
     CDS             19720..20628
                     /gene="yvcK"
                     /locus_tag="OPV72_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine diphosphate-N-acetylglucosamine-binding
                     protein YvcK"
                     /protein_id="HCR9914211.1"
                     /translation="MRNRTLADLDRVVALGGGHGLGRVLSSLSSLGSRLTGIVTTTDN
                     GGSTGRIRRSEGGIAWGDMRNCLNQLITEPSVASAMFEYRFGGNGELSGHNLGNLMLK
                     ALDHLSVRPLEAINLIRNLLKVDAQLIPMSELPVDLMAIDDQGHEIYGEVNIDQLATP
                     PQEIMLTPNVPATREAVQAINDADLILIGPGSFYTSLMPCLLLDELAQALRRTPAPMV
                     YIGNLGRELSLPAASLTLVDKLAMMEQYIGKKVIDTVVVGPRVDVSAVNDRLVIQEVL
                     EASDIPYRHDRQLLHNALEKALQALG"
     gene            complement(20723..22924)
                     /gene="slrP"
                     /locus_tag="OPV72_001897"
                     /pseudo
     CDS             complement(20723..22924)
                     /gene="slrP"
                     /locus_tag="OPV72_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459778.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system effector E3
                     ubiquitin transferase SlrP"
BASE COUNT         5332 a         6226 c         5946 g         5420 t
ORIGIN      
        1 agagattaat catgaaaacc attaaatatg ctgttgcagc catcgcgctt tccacccttt
       61 cttttggcgc ttttgccgca gaaccggtta gcgcgtctca gacgcaaaac ctgcataaaa
      121 tcggcgtagt gtctgccgat ggcgccacca cgctggatgg cctggaagct aaactggctg
      181 aaaaagccgc cgctgctggc gcaagcgctt ataacatcac ctccgccgta ggtaatgaca
      241 aaatgagcgg cactgcggtg atttataaat aatttacctg cccgccagat ttcaggctgt
      301 aacatcgctg ttgtttgaat tctgacgggt attaccctcg tctgtttgcc aacagaccca
      361 ctgctccaac cctcattaac cctgtttgtt acccttattt gcccgtccgc cactggacgg
      421 gcttttttta ttcgctaaaa gcctgttcga cgcgcgcaag cccgtcttct aacgtcgccg
      481 cctctcccgt cgcaaccaga caacaggcca tttgcgtttt taatgattgc ggcaccggct
      541 cgtggccggc aaggcagcgc tcaatccagc gcgcggtgat ttcaggatct ttagtcgcag
      601 gcagtgaaag cggctcgtcg tacgtgtcgc tctggcgctc atgcagtacc tgcacgccgc
      661 ggctatcaat caggctgatt tgcggacagc gttgcgggtt ggcatagact tcgccttcgg
      721 taccatgcat cagcaaagcc cacccgccaa tgcggctaaa aaaggtcgcc acacgcagaa
      781 catattcagg atgagaaacg cttgataaac gcagcgcggc atcctcagca aatggcgtcg
      841 ccagcttggc cagtgaatgc gcgctgttac gcacgcccat ccgccagcgc atcgctagct
      901 gtttttccag cggcgggcag agcgcgctca ccgggataaa caccggctgg cgcccgtcca
      961 gtttggcctg cgcttgtccg ccgtgtaggg tgggttcaat ccccatcagc tcaaatatag
     1021 tttccgtcag tacgcgggtc ggatcttcac tgacgccgtg tactacgact ggaaagccca
     1081 atttatgcag caagatagcc agcagcggcg ttaaattcgc ctgtttacgc gcgccgttat
     1141 agctgggaat aacgaccggc aacggcctat ctgcgggcgg tgtcagtttg atggcatgat
     1201 tctacatggc ttcataaaag cccagcattt cggcttcgcc ttcgccttta atacgcagcg
     1261 ccatcaatat actgcccatt tccaggtcgg ggacgtcgcc attcagcatt cgggtataca
     1321 aaccgcgcgc ggtatccaga tccagatcgc gggcgtgatt tttacctcgc ccgatctctt
     1381 tgatgatctt gcgataatcc attgaaagct ccttgaagtg tgctcacagc attaacaccg
     1441 tcggcggcgt gcaggttttg cttttggttt tactataacg tctggcacgg caggctgctc
     1501 tatcggaaaa acaggtaagg cattcagtaa acgctgtccg tagtttttgg tcaacaaccg
     1561 cttatcataa atgaccactt ctccccgaca ggcgtggcta cggatcaatc gccctacctg
     1621 ctgaattaaa ttaaaagacg cgcttggtaa gctttgtacc tcaaacggat aacgattcag
     1681 actttttagc cattcgcctt cggtgatcac gaccgggctg tcgatcggcg ggaaggcaat
     1741 tttatggata tggacctgcg tcagtagctc gcctttaaga tccagccctt cggcaaaaga
     1801 ctgaagccca accagcacgc tgcgttcgcc gctctccacc cgtttacggt gcagctccac
     1861 cagccggtaa cgcggctggt cgccctggac caggaggagt aagcgcacat cagcgacatg
     1921 ctccagaaaa cgctgcatcg cccgcccgct ggcgaacagt accagcatac catgatgttt
     1981 tttgctctcc agttgctcgc gaaaataggc tgccatttcg gcaatatgct gctcttcgtt
     2041 atcaatagtg ggttcgtagc gcatttgagg aatcaccagt ttcccctgtt ccacatgatt
     2101 aaacggcgaa tccagcgcca caaagcggtc gccggctttt tcttttaagc cgctcatttc
     2161 ctgcaggcgc gaaaagctat tgagcgagcg cagtgtcgcc gaggtgacaa taatgtgcgg
     2221 tacgctgcgc cataacaatc tttccagctg ctcgctgacg cggataccga cacaatggaa
     2281 ccagacgtgg agttgccctt cgcgtatttc acgcgtcgcc catttggaca ccggcgcgcc
     2341 tgaagactgc gccatcgaag ccagtcacca taatttactt tgcgcctcga acattcccag
     2401 cgcccggttc atctgtaaaa tcacccgatg caaacgcaca atatcgtgcg acccggtttt
     2461 ttcgctgaga tcgttgagaa aggactccgc cagcccacgc aacgtctcgg tcagcttcgc
     2521 cagtcgctgg cagatttcca tgacctcatc aggcaactcg cccattgcaa aacggtgctc
     2581 cgcctcctgc gctgcgggca tatacagatt aagaatggca ttgagcgagg cgatcagttc
     2641 gtacacctcc tcgcaatggg cgttaagtcg ctcaggattc gctaacggcg gcgtggtctt
     2701 agggcgaaat tgctccatgc aggtcgccac cagtttgctg aacaggtcca gttgcaagcg
     2761 ataccaggag gcggtaattt ccgcgctcat ctccagcgca tcgcgagcga catcgggcag
     2821 atgatgacct tcatccagta ccaacagcag atgctttggt tccggcagta cggcttcact
     2881 ttccatcgcc gccattacta gcgcgtgatt cgccaccacg acttccgctt cctgtatttc
     2941 acgtcgggcg acaaagaatg gacattcgcg gtaatagtga cagttgcggt tcagacaact
     3001 ggctttatcg gtacttaatc gccgccacag atcgtcgtca atagcaatgt cggtatgatc
     3061 ccgcagacca tcccatttgt aaccgtcaag atcccctttc agcctggcgc agcgcttttg
     3121 ctcttcctgg ttgttaggcg tcagttcgtc atcaagaaag gcgagcagat cctgctgcgt
     3181 aggctcgcta ctggcgagcg ccgccaggtt tcgcggacac acgtaacgcc cgcggccaaa
     3241 ggcggcggta aagcgcagat cggggatgat ttttcgtagc agcggcaaat ctttgctaaa
     3301 gatctgatcc tgtaacgcca cgttagcggt actgaccacc agtgtttttt gctcttcccg
     3361 ggcaatggcg ataccgggaa taagatagga gagggttttc ccgacgccgg tcggcgcttc
     3421 aatagccaga tgtctccctt cttccccggc cagcgttctg gcgacgtcag caatcatctg
     3481 ccgctgcggc gcacggggaa taaagtcggg aatctgatcc tgaagcgcct tataccaggc
     3541 ggcgatttgc gctttcagcg cagcggtcaa tgccatgaga aaacctgaag tactgtataa
     3601 acagccacta ttgtgtcaca tttcaggggc gggaagtacc ttttttgccg gttctggaag
     3661 gcggctcgca acgcgatgtg tattttgccg gatggcggtg caagcacctt acccggccta
     3721 cgtatttgca tagtccgtag gcccggtaag cgtcgcgcta ccgggcatgt tgccggataa
     3781 aatttactgg gcaggcgtga ttctgcgcgg gcgacgcggc ggacgtgctt tgtcgccagc
     3841 gggtttcccc tcgcctgtgc gcggttttgg tttcgccttc gccgccccgc tatcctgacg
     3901 tcgcggctgc tgactgcgcc ccgctccccc ctgattttgt ccgcgtccac gaccgccgcc
     3961 gcgctgctga cggccgttct gaatcggctc cgctttaatc gacgggtccg gctcatagcc
     4021 cggcgtcgta atgcgtggga tctctttttt cagcaatttt tcgatatcac gcaacagttt
     4081 atgctcgtca acacagacca gcgacagcgc ctcgccagtt gccgccgcgc gaccggtacg
     4141 gccaatacgg tgtacataat cttccggcac gttcggcagt tcatagttga ccacgtgcgg
     4201 cagctcttca atatccagac cacgcgccgc aatatccgtc gccaccagca cgcgaatatc
     4261 gccggattta aaatcggcca gcgcgcgggt acgtgcgccc tgcgatttat taccgtggat
     4321 cgccgcgctg cgaataccgt ctttattaag ctgttccgcc agatggttcg cgccatgctt
     4381 ggtgcgggtg aagaccaaca cctgctgcca gttgccctgg ccaatcatct gcgacaacag
     4441 ttcacgtttg cgttttttat cgacaaagtg cacgtgctgc gtcacctgct ctgaggccgt
     4501 gttgcggcgc gccacttcga tttccagcgg gttgcgcaac agcttttcgg cgagcgcttt
     4561 gatgtcgtcg gagaacgtgg cggagaacag cagattctga cgcttcgccg gcagtttcgc
     4621 cagcacgcga cgaatgtcgt gaatgaagcc catatccagc atacggtcgg cttcatccag
     4681 taccagaatc tcaatctgat ccagcttcac ggcattttga tgttccaggt cgagcagacg
     4741 tcccggcgtc gccaccagca catccacgcc gccgcgcagt ttcatcatct gcggattaat
     4801 gcttacgccg ccaaatacca ccagcgagcg aatattgaga tatttactgt aatctctgac
     4861 gttttcacca atttgcgccg ccagctcgcg ggttggcgtg aggatcaacg cacgtaccgg
     4921 gcgacgacct ttagcgtgcg gctgatgggt aatcagatgc tgcaacaatg gcagggtaaa
     4981 acccgccgtt ttaccggttc cggtctgggc gctagccatc agatcgcggc cttccagcac
     5041 ggcgggaatc gcctgttgct gaataggggt aggttcacgg taaccctgct cggcaatggc
     5101 gcgcaggata tcagggttta atcccaggga atcaaaagac ataactactc cggaccgccc
     5161 cgaccgttac cggtgtagtt ttcagggaga tgctcaaatt tggaatgaca aaaaccacaa
     5221 tgtcatgaag gggcggagtg tagcagtttt tgtgatgcgg cgcataaatt atcccgaaag
     5281 gtggcaaaga caaattaatc gaccacactg gacaagtgcc attatgagtc ataatcttaa
     5341 tcaatcgatt gattaataat tagggcgtgt gatgaatatt cccaccacga ccaccaaggg
     5401 cgagcaggcg aaaagtcagc tcattgccgc cgcactggcg cagtttggcg agtatggcct
     5461 ccatgccacc acgcgcgata tcgccgcgct ggcggggcaa aatattgccg ctattactta
     5521 ctatttcggc tcaaaagagg atttatacct cgcctgcgcc cagtggattg ctgattttct
     5581 tggcgaaaaa tttcgccccc atgctgaaaa agcggaacgt ctgtttagcc agcctgcccc
     5641 tgaccgagac gccatacgcg agctcattct gctcgcctgc aagaacatga ttatgctgct
     5701 gacgcaggaa gacaccgtta acctgagcaa atttatttca cgcgagcagc tctctcccac
     5761 atcggcctat caattggtcc atgaacaggt tatcgatccg ttgcacacct atctgacaag
     5821 attggttgcc gcttataccg gctgcgacgc caatgatacg cgcatgattt tgcataccca
     5881 tgccttactg ggcgaagtac tagcgtttcg tctcggcaaa gaaactattc tgttacgtac
     5941 cggctggccg cagtttgatg aagaaaaagc ggagctgatt taccagacgg taacctgcca
     6001 catcgatctt attctgcacg gtttaacgca aaggagtctg gactgatgaa aaaacctgtc
     6061 gttatcggac tggtaatcgc agcgatcgtc gctgtgattg ccggtggaac ctggtggtat
     6121 caaagtcggc aggacgatgg gctgacgcta tacggtaatg tcgatatccg taccgtcaat
     6181 atcagctttc gcgtcggcgg caggctggcg tcgctgaatg ttgatgaagg cgatactatc
     6241 aaagccggac aggtgctcgg cgaactggat cacgcgccat acgaaaacgc gctgatgcag
     6301 gcgaaagctg gcgtgtcggt cgcgcaggcg caatatgatt tgatgctggc aggctatcgc
     6361 gatgaagaga tagcccaggc cgccgccgcc gtcagacagg cgcaagccgc ctatgactac
     6421 gcgcaaaact tttataaccg tcagcaagga ttgtggaaaa gccgcaccat ttccgctaac
     6481 gatctggaaa atgcccgctc atcgcgcgat caggcgcagg cgacgctgaa gtccgcgcag
     6541 gataaactga gccagtaccg taccggtaat cgtgaacagg atatcgccca ggcgaaagcc
     6601 agtctggaac aggcaaaggc ccaactggcg caggcgcagc ttgatttgca ggacaccacg
     6661 cttatcgcgc ctgccaacgg aaccttgctc acccgcgcgg tcgagcctgg cagtatgctg
     6721 aacgccggca gcacggtatt aacactctcg ctgacccgcc ccgtctgggt gcgcgcctat
     6781 gtcgatgaac gcaacctcag tcagacgcaa ccggggcgcg atattctgct gtataccgat
     6841 ggacgtcctg acaaacctta ccacggcaag attggtttcg tttcccccac cgcggaattt
     6901 acgccgaaaa ccgtcgaaac gccggatctg cgtaccgatc tcgtctatcg cctgcgcatt
     6961 atcgtcaccg atgcggacga tgcgttacgc caggggatgc cagtcacggt gaaatttaat
     7021 gacgaggcac ggcatgagtg aggccgttat tacgctgaac ggtctgacga agcgctttgc
     7081 gggaatggat aaacccgccg tcgcgccgct cgactgtacc attcattccg gttatgtcac
     7141 cgggctggta gggccggacg gcgcaggaaa aaccacgctg atgcgtatgc tggcgggcca
     7201 gctcaaagcc gatggcggca gcgcgtccgt attgggcttc gacccgatac aaaacgacag
     7261 cgagctgcac gcggttctgg gctatatgcc gcagaaattc gggctgtatg aagatcttac
     7321 cgtcatggag aaccttaatc tctatgccga tttgcgcagc gttaccggcg agatacggga
     7381 aaagaccttt gcccgtttgt tggagtttac cgccctcggc cctttcactg gccgtctggc
     7441 gggaaaattg tccggcggga tgaagcaaaa actggggctg gcctgtacgc tggtcggcga
     7501 accgaaagtg ctgctgttgg atgaaccggg cgttggcgtt gacccgattt cacggcgcga
     7561 gttgtggcaa atggtccacg aactggcggg cgacgggatg ctgattttat ggagcacctc
     7621 ctatctggat gaagccgaac agtgtcgcga tgtgctgctg atgaatgaag gcgagctgct
     7681 ctatcagggc gaacctaaag cgctgacgca aacgatggcc ggtcgtagct ttctgatgag
     7741 tagtccacag gaaaacaacc gtaagttact acagagagcg ctcagactgc cgcaggtgag
     7801 cgacggcatg attcaggggc gttcggtacg cctgatcctg aaaaaagagg cgaccgcagc
     7861 agatattcgt caggccgaag ggatgccgga aatcaccctc aatgagaccg cgccgcgttt
     7921 cgaagatgcg tttatcgatc tgcttggcgg agcgggaacc tcggagtctc cgctgggttc
     7981 aatcctgcat acggttgaag gcactgccgg cgaaacggtg attgaagcgc aggaactgac
     8041 gaaaaaattt ggcgatttcg cggccacgga ccatgttaat ttcgtcgtac aacgcggcga
     8101 gatttttggc ctgctcggcc cgaacggcgc gggtaaatca accaccttta aaatgatgtg
     8161 cggcctgctg gtgccgacgt ccggcaaggc gctggtgctg gatatggacc tgaaagtcag
     8221 ctccggcaaa gcccgtcagc atctgggcta tatggcgcaa aaattttcgc tttacggcaa
     8281 cctgacggtt gagcagaacc tgcgtttttt ctccggcgtc tacggtttgc ggggccgcgc
     8341 gcaaaatgaa aaaattcagc gcatgagtga agcatttggt ctgaaaagca tcgcgtcgca
     8401 tcccaccgat gcgctgccgc tgggttttaa acagcgactg gcgctggcct gctcgctgat
     8461 gcacgaaccg gatattttat tccttgatga accaacgtcc ggggttgatc ccctcacccg
     8521 ccgtgaattt tggctgcaca ttaatagcat ggtggaaaaa ggggtcacgg taatggtgac
     8581 gacccacttt atggatgagg cggaatattg cgatcgcatc ggactggttt atcgtgggaa
     8641 gcttatcgcc agcggtacgc cggacgatct caaagcgcag gccgccgatg agcaacaggc
     8701 cgatccgacg atggagcagg cctttatcac tctcatcaat gactgggata aggagcatac
     8761 gcatgagtaa gtctctctcc tggcgccgcg tgcgtgcgtt gtgcgtcaaa gagacgcgcc
     8821 agatcgtgcg cgatcccagt agctggctga ttgcggtggt gatcccgctg ctgttgctgt
     8881 ttatttttgg ttacggcatt aacctcgact ccagcaagct gcgggtgggg attctgcttg
     8941 aacagcaaag ccaggaggcg ctggatttca ctcatgcgat gaccggttca ccctatatcg
     9001 acgcgaccat tagcgataat cgtcatgaat taattgaaaa aatgcaggcc ggacgcattc
     9061 gcggactggt ggtgattccg gtggatttcg cgcagcaaat ggcgcgcgac ggtgacagcg
     9121 cgccgattca ggtgattacc gacggcagcg agccaaatac cgccaacttc gttcagggct
     9181 atgttgaagg catctggcaa atctggcaac agcagcgcgc ggaagatcgc ggcgacacct
     9241 ttgaaccgct tatcgacgtc cagacgcgct actggtttaa cccggcggcg atcagtcagc
     9301 attttatcat tcccggggcg gtgaccatta tcatgacggt aattggcgcc atcctcacct
     9361 cgctggtcgt tgcccgcgaa tgggaacgcg gcacgatgga ggcgctgctc tcaaccgaag
     9421 tgacgcgtgt tgaactgctg ctgtgtaagc ttattcccta ttattttctc ggtatgctgg
     9481 cgatgctgct ctgtatgctg gtatcggtgt ttattctcgg cgtgccgtat cgcggttcgc
     9541 tggtaattct gtttatcatc accagtctgt ttttactgag tacgctgggg atggggctgt
     9601 tgatttccac catcactcgc aaccagttta acgccgcgca ggtggcgctg aacgccgcgt
     9661 ttttgccttc gattatgctg tccggattta tcttccagat agacagtatg cctgcggtga
     9721 tccgcgcggt gacctatatt attccggcgc gctattttgt cagcaccctg caaagtctgt
     9781 ttctggccgg caatattccg gtcgtgttag gcgttaacgt actgttttta atcgcctcgg
     9841 cggtgatgtt tattggcctg acgtggctaa aaaccaaacg acggctggat taaatatgtg
     9901 tatggataat tgtcgtcgta ggccggataa ggcgctcacg ccgccatccg gcattatgcc
     9961 tgatgcgctt tgcttatcag gcctacaaac tggactgaga ggacgggcat gtttcatcgt
    10021 ttatggacgt taattcgcaa agaactgcaa tcgcttttac gcgaaccgca aacgcgcgcg
    10081 atcctgattc tgccggtgct gattcaggtc atcctgtttc cgttcgccgc gacgcttgaa
    10141 gtcactaacg cgactatcgc catctataac gaagataacg gcaaacattc ggtagaactt
    10201 acccagcgtt ttgcccgcgc gaaagcgttt acccatgtgc tattgctgaa cagtccgcag
    10261 gagatccagc cgactatcga tacgcaaaaa gcgctgctgc tggtgcgctt cccggcggat
    10321 ttctcgcgga atctggatac cttccagcct gcgccgatgc aactcattct tgatggacgt
    10381 aactccaaca gcgcgcaaat tgccgccaat tatctgcaac agatcgtcaa ggagtatcag
    10441 cagacattga tggacggcaa gccaaagccc aacaatagcg aactggtggt acgcaactgg
    10501 tataacccga atctggacta caagtggttt gtggtgccct cgctgatcgc catgatcacc
    10561 actatcggcg tgatgatcgt cacttcgctg tccgtcgccc gcgagcgtga acaaggcact
    10621 ctggatcagc tgctggtctc tccgctcacc acctggcaga ttttcgtcgg caaagcggtg
    10681 ccggcgctga ttgtcgcgac cttccaggcc acgatcgtgc tggctatcgg catttgggca
    10741 taccaaattc ccttcgccgg ttcgttagcg ctgttttatt tcacgatggt gatttacggg
    10801 ctgtcgctgg taggctttgg cttgctgata tcagcacttt gcgccacgca acagcaggcg
    10861 tttatcggcg tctttgtctt tatgatgccg gcgattttgc tctcgggtta tgtctcgccg
    10921 gtggaaaata tgccggtctg gctgcaaaac ctgacgtgga taaatcctat ccgccacttt
    10981 actgatatta ctaagcaaat ttatcttaag gacgcgagtc tggggattgt ctggggaagt
    11041 ttgtggccgc tactggtgat agcggccacc acgggttcag cggcgtatgc gatgtttaga
    11101 cgcaaagtga tgtagctttt tatctttcgc cagtagcgag accacggcgg gcccggccag
    11161 gatagccagc cccgccagcg ccagtaaaac attgttttgc aatacgcggg atagcagcca
    11221 gaggacaatc agcgcggtgc caaagtacca ggtggtagtc agctcttcca gcacatccgc
    11281 cacatcgcgc cagcgctgct catgatggcg ctgcaacgcc agcatcaata gtaccgtcac
    11341 gccataaagc acgcataatc ccaggccgac gcgcactaat gtgccgctca tccagcctat
    11401 taccagcatc gccactacca gtaaatgcaa cataatctgc caacaaccga ggccggttgc
    11461 gacacgaacg cgttgttgcc acttcatggc ttttctcctg aagcattttt ctctcattat
    11521 tcagagtacc gaactttacg gaaaattccg taagaccgca tctttttgtg acgacgacta
    11581 cactatttca atcaggatag tgacgcggac aggaagaaaa tgactcaaca cacgcgaaat
    11641 ttttcattca aagtgctcac aattaatacg cacaaaggtt ttaccgcctt taataaacgc
    11701 ttcatcctgc cggagctgcg cgacgccgtc agaacggtcg gcgccgatat cgtctgtctg
    11761 caagaagtga tgggcgcgca tgaagtgcat ccgctgcata tcgaaaactg gccggacact
    11821 acccactatg aatttttggc cgacaccatg tggagcgatt tcgcctatgg ccgtaatgcg
    11881 gtctatccgg aaggccatca cggtaacgcg gttctttctc gctatcccat tgaacattat
    11941 gaaaatcgcg gcgtctcggt cggcggtagc gaaaaacgcg gcgtgctcta ttgccgcatt
    12001 acgccgccca tgctcaaccg ccctatccac gtcatgtgcg tacatctcgg cctgcgggag
    12061 agccaccgcc aggcgcagtt aaccatgctg gcgggatggg tgaatgcctt gccggaatca
    12121 gaaccggtgc tggtggccgg agactttaat gactggcggc aaaaggccgg cccgccgtta
    12181 aacgcggccg ggctggagga gatattcacc cgtgcccatg gccgaccggc gcgcacattc
    12241 ccggtgagta tgccgctgct gcgactcgat cgtatttacg tcaagaatgc gaacgccagt
    12301 tctcctgggg cgctaccgtt gcggaactgg cgacatttat cagaccatgc cccccttagc
    12361 gcggagatcc atctatgaaa tgcggctggc gtgaaggtaa tcaaattcag ctactggaaa
    12421 acggcgacca gttctatcct gccgtgtttg aggctatcgc tcaggcacag caaaaaatca
    12481 ttctggaaac ctttatcttg tttgaagatg aggtgggtaa aaaactccat gccgctctgc
    12541 taaaagctgc acagcgcggc gtaaaagccg aagtattact cgacggctac ggctctcccg
    12601 atctcagcga cgcgtttgtc ggcgaattaa cctcggcggg cgtgattttt cgctattacg
    12661 acccccgccc gcgtctactg gggttgcgaa ccaatatctt ccgccgaatg caccgcaaaa
    12721 ttgtggtgat tgatgatcgt attgcctttg tcggcggcat taactactcc gccgaacata
    12781 tgtcggatta cggcccgcag gcgaaacaag actacgcggt acgggtcgaa gggcctgttg
    12841 tggccgatat cctgcaattc gaagtcgaga atctgccggg gcaaagcccc gcgcgccgct
    12901 ggtggaagcg ccatcatcag gctgaagaaa atcgccaccc cggcgaagcg caggcgctgt
    12961 ttgtctggcg ggataatgaa gaacaccgcg acgatatcga acgtcattat ctgaaaatgc
    13021 tgacccaggc aaagcgtgaa gtgattatcg ctaacgccta ttttttcccc ggctatcgct
    13081 tgctccacgc aatgcgtaaa gccgcccgcc gtggcgtgag cgtaaaactg attgtccagg
    13141 gagaaccaga catgccgata gtcaaagtcg gcgcgcggtt gctctataac tatctggtga
    13201 agggcggcgt gcaggtttat gaataccgac gccgtccgct gcatggcaaa gtggcgctga
    13261 tggacgatca ctgggccacg gtagggtcga gtaatctcga tccgctcagc ctgtcgctta
    13321 accttgaagc taacctgatc attcacgatc gtacttttaa ccagacccta cgcgataact
    13381 tacaaggcat catcgtgaat gattgtaagc aggtcgatga gtctatgctg ccgaaacgta
    13441 cctggtggaa cctgaccaaa agcgtgctgg cgttccactt tttacgccat ttcccggcgc
    13501 tggtcggctg gctacctgcg cataccccgc atctggcgca ggttcccccg cctgctcagc
    13561 cggaaatgga aacccaggat cgcgttgatc cagaaaattc aggagtgaag ccctaatggc
    13621 taaatcgcat ccgcgctggc ggctggctaa aaaagtgctg acctggctgt tttttattgc
    13681 ggtcgtcgtt ctgctggtgg tttatgctaa aaaggtcgac tggggtgatg tctggaccgt
    13741 catccgcgac tataaccgca cggcgctttt aagcgctgta ggactggtga tcgttagcta
    13801 tcttctgtac ggctgctacg acctgcttgg acggctttat tgcggccata agctggcgaa
    13861 gcgacaggtg atgttggtat cgtttgtctg ctatgcattc aacctgacgc tcagcacctg
    13921 ggtcggcggg atcgggatgc gttaccgact atactctcgc ctcggattgc ccggcagtac
    13981 tattacgcgc attttctcac tcagcattac cactaactgg ctgggctata ttctgcttgg
    14041 cggcatcatt tttaccttcg gcgttgtcca gcttcccgac cactggtata tcgatgaagg
    14101 cacgctacgt attctcggta tcgttttatt gttgattatc gcggtctatc tgtggttttg
    14161 cgcctttgcg aagcggcggc atatgacgat taaagggcag aaactggtgc tgccgtcatg
    14221 gaaattcgcg ctggcgcaga tggcgatctc cagcgcgaac tggatggcga tgggcgccat
    14281 catctggctg ctgatgggtc aggatgtgaa ctatttcttt gtactgggcg tactgctggt
    14341 gagcagtatc gcgggcgtca tcgtgcatat tccggcaggc atcggcgtgc tggaggccgt
    14401 attcctcgcg ttgctggcgg gcgaacatac gtcgcaaggc acgattatcg ccgccctgct
    14461 cgcgtaccgt gtgctttact attttattcc cctgttgctg gcgctggtgt gctatctgat
    14521 cctggagagc cgggcgaaga agttgcgggc gaaaaacgag cgggcgatgg cgaaatgaat
    14581 ttaagcagac gcgttttcgc tttccagcac aacgcgtttt atccggtaaa aataaacata
    14641 tgctgagaaa aaagacgtat tcatctgtaa gcgggaaaaa agcagcaatg accagctaaa
    14701 cagcagcagg agcacttcgt taaactcacc catgaatact gatgacaggg tacagaacgt
    14761 tgccaacgta acggaaataa tggccagcaa tagcacatac cggtaaataa tgaccccgct
    14821 catgttccca tgacaatccg gtaatgaaat gagaaatcag cgctggcggg catttcttat
    14881 taaaatcctc accgccattt ttaatggcgc gagtgacgtc tttagcttca caaaacgcta
    14941 accaaaattg tttgccacat aatttactca ttatacccat catcaccaac ctgaataaaa
    15001 aacctgcaac acctacggcc tgaaagataa tagtatttcc agaatcatca aaatgatata
    15061 acgacacagc gtaaccacag cattaataat gccaaggtaa agcgtcagcg cgccaaataa
    15121 agcgcaacga ggcagggatg aaaactcgct gtggtataac atgcgggcat aaccatgaag
    15181 tgtcgatttt tctagtgctg taatcaatgt ccataccaat accgtcagca cactgactat
    15241 ccagaccaga gtgctactgg ccaccaggct attgacaact atcgcagcga tgatcccgct
    15301 taccgccata aaaattaacg gcctgaatag accagaactg atattcaggt agaaaataaa
    15361 taaggcatta agactaaaca tgattccaac aatcacgaaa atggtcgcgc cacctgagaa
    15421 aaggtaagct aatgacacgc cggtaagcgt aatgatggca atatatatca acgttgcgac
    15481 aacagtgcca aagcgggaaa gacaggtaac ggccccatac cccaggccaa gcaaaagtgc
    15541 tgatatccac aaaacaacaa caggttgaac gtgagttatc aaaaaatgac tatacaacgt
    15601 taaccatata ataccggcgg tacaccatag tcccagcgca gtataccaat aggtaaggga
    15661 taacattgtc gcgggaataa atgctatttg ccgtatacgt attgcagcca gaggtcccac
    15721 ttgtcattta tcactcttct tattatcacc gtaataagaa tggcaagcgc aggaaaatat
    15781 ttctaagatg tttatgctgt tttgccctaa atatagtcct aaaaaaaatc ctggcgcagg
    15841 gccaggattt taagagatca atatgattag cggcgattgc caaaaatacg cagtaacatc
    15901 aggaacaagt tgataaagtc caggtacagc gttaacgcgc cgagaatcga atacttacgc
    15961 agattagcgc tatcgcgggt atctatttgc tcgccgatat ttttcagttt ctgcgtgtca
    16021 taggcggtca gaccgacaaa caccaccacc ccgatatagg ttaccgccca catcagcgct
    16081 tcactcttca gccagaaatt gaccagcgag gccagaacga taccaataag cgccataaac
    16141 agcatattgc cgaaaccgct aagatcgcgt ttagtggtgt acccatacag gctcatggcg
    16201 ccaaacattc cccccgtcac cacaaacgtg ctggcgatgg aggaataggt gtaaacgata
    16261 aaaatactgg ataacgtcaa atccggttag cgccgaatag agcataaaca gcgtcgtcgc
    16321 cattccggcg ctaagtttat gcaccagtcc cgacagaaca aacaccagcg caagctgagc
    16381 aatgattaag ccaaagaagg tgatcttact ggaaaagaca aacatcatga cggctggcgt
    16441 attagccgca taccacgcga taaacgcggt cagtaacagt ccgaccgtca tccagccata
    16501 cacttgcgcc atataggtct gcaggccaga ccgcgcctgc actattgaat cagatcgtgg
    16561 aaatctgtcc atgatgaact cctgtgtgga aatgataccc taaagcgtat cacattctgc
    16621 taccaacgtt tcgccaactg ctggtcgctg tcgcgcgctt cgacccagcg atcgccttcc
    16681 ggcgtggctt cacgcttcca gaacggcgca cgggttttca gataatccat aatgaactga
    16741 ccggcgtcga acgcgctact gcggtgcgcg ctggtgacgc cgacaaacac aatctcatcg
    16801 cccggccata attcgccaac gcgatgaatc accgtgaccc gccccagcgg ccagcgggaa
    16861 cgcgccttcg cgacgatctc cgccagagct ttctcagtca tgccgggata atgctccagc
    16921 gtcagcgcct taacgctatc gcccaggtta tgattgcgca cttttccggt aaaggtgacg
    16981 accgcgccgt cttcgtcgcg cgccgccagc caggaatatt cctccccgac gctaaacggc
    17041 gcagggccga ctacaattcg cgtttcgtgc atgttagccc cccgtgactg gcgggaaaaa
    17101 cgccacttca tcgcccgccg tcagcggatg gtcaaaactt accagcgtct ggttgaccgc
    17161 cgccaacagc ttgccgtctt ccagcgccag cgcccaacga tcgctctttg tcgccagatg
    17221 ctgtcgcagc gactcaacgg tggaaaaatc tgctggaaga tccagcgcat cagttcctgt
    17281 aagctcgcga acgtgggcga agaaaagcac tttaatcatg cgcatccacc ttaaaatccc
    17341 ccgatttgcc gccgcttttc gccagcagac gcaccggacc aattactata tctttttgta
    17401 ccgctttgca catgtcgtag atggttaacg ccgcgacgga cgccgcggtt aatgcttcca
    17461 tttcgacgcc ggttttaccg gtcagacggc acagagactc aatacgtaca cggttatgct
    17521 ccggctcggc ctgaagctga atctccactt tacttagcag tagcgggtgg cacagcggga
    17581 tcagctccca ggtgcgttta gcggcctgaa taccggcaat acgggcagtc gcgaaaacat
    17641 cgcccttgtg gtgtttgcca tcaacaatca tcgccagcgt ttcactacgc atggtaacga
    17701 atgcttccgc ccgtgcttca cgaacggttt ccgctttcgc ggaaacgtcc accatgtgcg
    17761 cttcgcctgc ggcgtttata tgggttaatt gcgacatcgt tatttcttta aatgagggtg
    17821 aaaattacat gggcgtgtac gggcatccag ctgcggcgca atgatattct cccatgcggt
    17881 tctgcacgct tttgtggagc ccggcatggc gaaaatcaag gtgttattcg ccacgccagc
    17941 taccgcgcgc gactgcagag ttgcggtgcc gatctcttca aacgagagca tgcgaaacac
    18001 ttcgccaaat ccttccactt cacgatcgaa cagcggcaac agcgcttccg gcgcctgatc
    18061 gccttcggtc aaaccggtcc cgccagttat caatacgacc tgcacctcat cactggcgat
    18121 ccaggcggaa acctgggcgc gaatcgcgta acggttctct ttaacgatgg ctttcgccac
    18181 cacttcatgc ccggcctcct gcgccgaatc acgcagataa tgaccggagg tgtcgtcttc
    18241 ttcgccgcgt cggctggaaa cagtaagaat agcgatgcgg gtcgggataa attcagcgct
    18301 gacctgactc atctgaaatc tccttattaa ggattaaccg ccaatgtaag ataaattttg
    18361 cgtaatacca gtattgctct ggtgaaggaa atgggtctgc tttttctccc gcaacgcgtc
    18421 ggaaatacgt tcctcaagcg cgtattgctg cgcatcatcc tgtaacaggt cgcgtaaact
    18481 cacgccgccg tcgccaaaca gacataaatg cagcttaccg acggacgaaa cacgcaggcg
    18541 gttacaggtg gcgcagaaat ctttttcgta cggcataatg agaccgatct caccggcgta
    18601 atcggggtga caaaaaacct gcgccggacc atcgctacgc tggcggagct ggtggatcca
    18661 accgcgctta atcagctcgt cacgtaatac ctgacccgaa atatgatgtt tgcggaagag
    18721 atcgctcccc tcgcccgtct ccataagttc aatgaagcgt agctgaatgg ggcgaggctg
    18781 aatccaggca aggaaggtat ccaactgatg gtgattcacg tcgcgcatca gcacggtgtt
    18841 gactttcacc ttttcgaaac cggcgtcaaa ggcggcatcg atgcccgcca tcacctggcg
    18901 gaatttgtcc tgaccggtaa tcgcatggaa ctgacgcgca tccagactat ccacgctaac
    18961 attgacgccc gtcagccccg cttcgcgcca gttcgcggca tcgcgcgcca gtcgataacc
    19021 gttagtggtc accgcgatct ggcgaatagc atcattttca cccacggcgg caatgatgtc
    19081 ggtaaaatcg cggcgtaatg aaggctcgcc gccggtaaga cgcacctttt ccgtgccaag
    19141 actggcaaaa gcgcgcgtaa cgcgacgaat ttcatcgacg gtaaggaaac cgttgttagt
    19201 gacgccgcca ggtttgtagc catccggcag acagtaggtg caacgaaagt tacacacatc
    19261 ggtaatcgac aaacgcaagt agtaaaactt acgcgcgaaa gcatcggtaa gttgtgaagc
    19321 catgtacacc tttccaaata cgggaggcgg agtcatttct tcctgcgccc tggtggcaaa
    19381 cgttaaacgt tgtcacggcc aaagcaccat atcaaaaatg acccaggtgc agaggctaga
    19441 gtgtttattg tggttacgcc gatactagcg tgtaaatgac aatttcgcca tcacgctttc
    19501 gctatataaa catatacata gcgatatgat cgtgctattt agcgacagaa tacgtgaaaa
    19561 tcacactttt acattgatat atatcattta gccgtggtaa cgccctcgct ataaaggggt
    19621 agtcgggaat aattaattgt cttttagccg gtcggctaat tgctgaaaac ccgcgacttg
    19681 cgctactgta gcgctgctta tttgacttca ggaattttta tgcgcaatcg tacgctggct
    19741 gaccttgatc gtgtcgttgc cctcggcgga gggcatggat taggacgcgt cctctcctcg
    19801 ctttcttcat taggttcgcg cctgaccggc attgtgacta ccacagataa cggggggtca
    19861 actggccgta ttcgccgctc ggaaggcggg atcgcctggg gcgatatgcg caactgtctg
    19921 aatcagttaa ttaccgaacc cagcgtcgca tccgctatgt ttgagtaccg ttttggcggt
    19981 aatggcgaac tttctggtca taacctcgga aatttgatgt taaaggcgtt agatcacctg
    20041 agcgtgcggc ctctggaagc gattaattta attcgtaatc tgcttaaagt ggacgcgcag
    20101 ctgatcccga tgtcggagct accggtagat ctgatggcga ttgacgatca ggggcatgag
    20161 atttatggcg aggtgaatat cgatcagtta gcgacgccgc cgcaggagat catgttaacg
    20221 ccaaacgttc cggcgacgcg ggaagcggta caggccatta atgacgcgga tctgattctg
    20281 attggccctg gcagttttta taccagcctg atgccttgcc tgctgctgga tgaactggcg
    20341 caggcgctgc ggcgcacccc agcgccaatg gtgtatatcg gcaatctggg tcgcgaactg
    20401 agtctgcccg ccgccagttt aacgctggtc gataagctgg cgatgatgga gcaatatatt
    20461 ggcaaaaaag tcattgacac agtagtggtt gggccgcgag ttgacgtcag tgcggtgaac
    20521 gatcggctgg tgattcagga agtgctggag gccagcgata tcccctatcg ccacgatcgt
    20581 cagttattac acaatgcgct ggaaaaagcg ctacaggcgt tgggttaagc ccgtttaccg
    20641 acgacgctgc gcttatcaga agcctgttta caccgaaggg taaacaggct ctctccctct
    20701 tctgataaac tgcgttcagc tatcaccagt aggcgctcat gagcgagctc acctcttttt
    20761 tcagcaatat attctccatg atctcagtaa agagggtctg attgatctct tccattatcc
    20821 gcattccagc catgcgctct gcgtcaggat cacctgctat tcctaacgct tccagttcag
    20881 cattgacccg gctctgatac tcatccgttt caatacactc agcccttttg gccatcattt
    20941 cacgccactc ttctggcgct atacgctcca gcactttatg ccacggcccc cacagcgcaa
    21001 accatttgtg aaaatcccta ttttcagcaa tttttatcct tatttccgcc tcgtccaggt
    21061 cagactcagt gatacccgaa acgttataaa atcgcatatc ctgggtcatt gttgtcagcg
    21121 acagcgactc tcgtaactga ttctgaaaac ccagatatac ttcgatttcg tcaataaaaa
    21181 acagccgttt taccttttct ctggcgagcg attctatttg ctccagccga aagatttcac
    21241 gccccgccat aatcagttcc gctaagtggc tatcaaaggc gcctctttca gcatcatgaa
    21301 ccaacgtcgc ttcctgcatt tgatggtatg ccagtgtgac ccgatcttca cagcttatcg
    21361 ttgcatccat cgctataata aatgcggttt ctcttagtgc gctatcatca gccaggcgca
    21421 ttagccaggc ggagacttgt tccttaaaat ccgaatgtcg ggtgttctgc gtatcgctaa
    21481 gacgatccag aaacatgctg aaggctgccg cgtttacttc cgtctcaaac gcccgccatt
    21541 ggttgacgtc ttcctcctcg agattggtta gccacccctg gacagcttga tgcagtggtc
    21601 gagttacccg aacaattgaa aagtcgccca tggcaaaaaa tacctggggt ccctgataac
    21661 ccgcagagga cattagccgc tgcatattct gtattgttcg ttctgaaaaa ggattatgtt
    21721 ctacgattat tcttgtaggt tgaggtcctt caccacgaaa acggggtaac gactctggga
    21781 gacggaccag gcgattgcga gaggcctgca ttatttgtaa tgccgccggg aggttttccg
    21841 gtagattact caatgcgtta cgggaaacgt ccagcgttgt tatcgtggga ggtagtgttt
    21901 caggcagaac agtaatctga tttttactta catccaggaa ctgtaattct ggtggtaacg
    21961 atgcgggcag actggttaaa gcattttcgc cggcctccag attcttcagg cccggcggca
    22021 atgtttcagg cagagcggtt aacgaattac tctgcacatt caaatgggta atccctgacg
    22081 gaagatgttc tggcagtgtc cttatgcggt tatcataaac gctcaggtac cgaagttcct
    22141 caggtagatt ttcaggtaag gaactaattt tattatgaaa aagatccagc gattgaagcg
    22201 ctgaaggcaa acgttccggc aattcagtaa tacggttaat gctcagctcc attttctgta
    22261 tggtatccgg taacgtggca gggatactgg ttagctgatt actgctggca tacagggtct
    22321 ttatatttcc ctgtaaattt tccggcaaac ttttcagttc attgttatcg agtatcagag
    22381 tagttatctg ctcaggaata caggcgggta tagtggtaag tcctaatatt ttcagacgga
    22441 gttccgtctt attatttttc aggcagtcac gcatccgttg tacggcttct tcacgatttg
    22501 ctgcctcttc cgctggcgcc gcttttacct actcagacca gattaactca taattcacag
    22561 tatctttgga gccggaagcg ctactcgcct gcttgctttc tgtcacacgg gtataggtga
    22621 ctgacttccc ccctccctca acggtatagc cttctgtatt aaaaactata gacagaattt
    22681 cctgactatt ttcactcaaa atacagtatt ggtctgcccc tcctctacta tactgaatat
    22741 tatccgcata cgccgggaaa gctaacatcc ttaaacattc aaacttgctt ttgatctctt
    22801 ctggcgaggc ggtttcaggt ggatgacaaa gataagcgat tcagctttgt gcttcaacct
    22861 gatgttctga agagaaaaag gcacttattt tattccatat ctcttctttt aaaggcacct
    22921 ctgt
//
LOCUS       DAJVBX010000057        22835 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.057, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000057 DAJVBX010000000
VERSION     DAJVBX010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 22835)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22835)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22835
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.057"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(154..996)
                     /gene="sseA"
                     /locus_tag="OPV72_001898"
     CDS             complement(154..996)
                     /gene="sseA"
                     /locus_tag="OPV72_001898"
                     /EC_number="2.8.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-mercaptopyruvate sulfurtransferase"
                     /protein_id="HCR9914212.1"
                     /translation="MTTAFFVAADWLAEHIDDPEIQILDARMAPPGQEHRDMAGEYRA
                     GHIPGALFFDIEALSDRASPLPHMMPRPEAFAVAMRELGVRQDKHLVIYDEGNLFSAP
                     RAWWMLRTFGAEKVSILAGGLAGWQRDEWLLREGEEAHEGGEFEAKFTPQAVVRLTDV
                     LLASHEKTAQIVDARPAARFNAQADEPRPGLRRGHIPGALNVPWTELVYEGELKTTDE
                     LNEVFFSHGVSFDRPIIASCGSGVTAAVVVLALATLDVPDVTLYDGAWSEWGARTDLP
                     VEPA"
     gene            1205..6139
                     /locus_tag="OPV72_001899"
     CDS             1205..6139
                     /locus_tag="OPV72_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-2-macroglobulin family protein"
                     /protein_id="HCR9914213.1"
                     /translation="MKHLRVVACMIMLALAGCDNNDKTAPTTKSEAPAVAQPSPAQDP
                     SQLQKLAQQSQGKALTLLDASEAQLDGAATLVLTFSIPLDPEQDFSRVVHVVDKKSGS
                     VDGAWELAPNLKELRLRHLEPERVLVVTVDPAVKALNNATFGKSYEKTITTRDVQPSV
                     GFASRGSLLPGKIAEGLPVMALNVNHVDVNFFRVKPGSLASFVSQWEYRSSLSNWESD
                     NLLKMADLVYTGRFDLNPARNTREKLLLPLSDIKPLQQAGVYVAVMNQAGHYNYSNAA
                     TLFTLSDIGVSAHRYHSRLDIFTQSLENGAAQSGIEIVLLNDKGQTLAQATSDAQGHV
                     QLEADKAAALLLARKEGQTTLLDLTLPALDLSEFNVAGAPGYSKQFFMFGPRDLYRPG
                     ETVILNGLLRDSDGKTLPDQPVKLEVVKPDGQVMRTVVSQPENGLYRLNYPLDINAPT
                     GLWHVRANTGDNLLRSWDFHVEDFMPERMALNLTAQKTPLAPADEVKFSVVGYYLYGA
                     PANGNTLQGQLFLRPLRDAVAALPGFQFGNIAEENLSRSLDEVQLTLDKGGRGEVSAA
                     SQWQEAHSPLQVILQASLLESGGRPVTRRVEQAIWPADTLPGIRPQFAAKAVYDYRTD
                     TTVNQPIVDEDSNAAFDIVYANAQGEKKAVSGLQVRLIRERRDYYWNWSESEGWQSQF
                     DQKDLVEGEQTLDLNADETGKVSFPVEWGAYRLEVKAPNETVSSVRFWAGYSWQDNSD
                     GSGAARPDRVTLKLDKANYRPGDTMKLHIAAPVAGKGYAMVESSDGPLWWQAIDVPAQ
                     GLELTIPVDKTWNRHDLYLSTLVVRPGDKSRSATPKRAVGLLHLPLGDDNRRLDLALE
                     SPAKMRPNQPLTVRVKASVKHGEMPKQINVLVSAVDSGVLNITDYATPDPWQAFFGQK
                     RYGADIYDIYGQVIEGQGRLAALRFGGDGDDLTRGGKPPVNHANIIAQQAQPITLNEQ
                     GEGVVTLPIGDFNGELRVMAQAWTADDFGRGESKVVVAAPVIAELNMPRFLAGGDVSR
                     LVLDVTNLTDRPQTLNIALAASGLLELLSQQPQPVNLAPGVRTTLFVPVRALEGFGEG
                     EIQATISGLNLPGETLGAQHKQWQIGVRPAWPAQTVNSGIALAPGESWHVPEQHLANV
                     SPATLQGQLLLSGKPPLNLARYIRELKAYPYGCLEQTTSGLFPALYTNAAQLQSLGIT
                     GDSDEKRRAAVDIGISRILQMQRDNGGFALWDENGAEEPWLTAYAMDFLIRAGEQGYS
                     VPPEAINRGNERLLRYLQDPGTMLIRYSDNTQASTFAAQAYAALVLARQQKAPLGALR
                     EIWERRSQAASGLPLMQLGIALNTMGDARRGEEAITLALNTPRQDERQWIADYGSSLR
                     DNALMLSLLEENNLRPDAQNALLSSLSEQAFGQRWLSTQENNALFLAAHSRQASAGAW
                     QAQTSLEAQPLSGDKALTRNLDADQLAALEVTNTGSQPLWLRLDSSGYPSSAPEPASN
                     VLQIERQILGTDGQRKSLSSLRSGELVLVWLTVVADRNVPDALVVDLLPAGLELENQN
                     LADSSASLPESGSEVQNLLNQMQQADIQYMEFRDDRFVAAVVVNEGQPVTLVYLARAV
                     TPGTYQLAQPQVESMYAPQWRATGASEGLLIVTP"
     gene            6140..8455
                     /gene="pbpC"
                     /locus_tag="OPV72_001900"
     CDS             6140..8455
                     /gene="pbpC"
                     /locus_tag="OPV72_001900"
                     /EC_number="2.4.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461466.1"
                     /note="penicillin-binding protein 1C; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase PbpC"
                     /protein_id="HCR9914214.1"
                     /translation="MNGWRGKRGRWLWLAGAPLFIFLALWAADKLWPLPLNEVHPARV
                     VVAHDGTPLWRFADAGGIWRYPVTIEEVSPRYLEALINYEDRWFWQHPGVNPFSVARA
                     AWQDLTAGRVISGGSTLTMQVARLLDPHSRTFGGKIRQLWRALQLEWHLSKRDILTLY
                     LNRAPFGGTLQGIGAASWAYFGKPPARLSYADAALLAVLPQAPSRLRPDRWPTRAEAA
                     RNKVLDRMAEQGVWPAETVRESREEPVWLAPRQMPQLAPLFARMMLSKSRSDKIVTTL
                     DAGLQRQLEDLARAWKGRLPARSSLAMIVVDHTDMSVRGWVGSVDLNDDSRFGHVDMV
                     TAIRSPGSVLKPFVYGLALDDGLIHPASLLQDVPRRTGDYRPGNFDSGFHGPVSMSDA
                     LVRSLNLPAVQVLEAYGPKRFAAKLRNVGLPLYLPAGAAPNLSLILGGAGARLDEMAA
                     AYSAFARHGKAAKLRLQPDDPLSERPLMSPGAAWIIRRIMADEAQPLPDNALPRIVPL
                     AWKTGTSYGYRDAWAIGVNARYIIGIWTGRPDGTPVVGQFGFASAVPLLNQVNNLLLA
                     HTGRLPEDPRPQTVSRGVICWPGGQTLPAGNSNCRRRLATWLLDDSQPPTLLLPEQED
                     INGIRFPVWLDDTGRRVAADCPQARAHTFIVWPRPLEPWLPPAERRSARLPAASDHCP
                     PLQGNDAAPLMLSGVRDGAVIRQLPGQENVTLPVSTTGGKGRRWWFLNGEPVNGENNR
                     LSLLLNIAGRYQLVVMDESGQVAAVNFELIR"
     gene            8584..10988
                     /locus_tag="OPV72_001901"
                     /pseudo
     CDS             8584..10988
                     /locus_tag="OPV72_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461465.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
     gene            10985..11614
                     /gene="dmsB"
                     /locus_tag="OPV72_001902"
     CDS             10985..11614
                     /gene="dmsB"
                     /locus_tag="OPV72_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethylsulfoxide reductase subunit B"
                     /protein_id="HCR9914215.1"
                     /translation="MSQFTHYPPVSDKQLGFFIDSSRCSGCKACQVACKDKNNLEVGR
                     RFRRVYEVKGGSFIPTGQGRVSNNVFAYTLSISCNHCADPVCTKNCPTTAMHKRPGDG
                     IVRVDTDKCVGCGYCAWSCPYGAPQLNEQTGQMSKCDMCVDLLAKGESPGCVATCPLE
                     AIKFGPIDELRAKYGSVCDVNGLPDSSITKPNLVVKAHQGAEKEGKRHA"
     gene            11607..12416
                     /locus_tag="OPV72_001903"
     CDS             11607..12416
                     /locus_tag="OPV72_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461463.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase anchor subunit
                     family protein"
                     /protein_id="HCR9914216.1"
                     /translation="MHELPLLIFTLCLQGSVGVTLWLALGRQYAVEGRVPARGALPAM
                     AGAFVLACVGLLASALHMGYPLNALNALRHVASSWLSREIVFASLYLAALGLGVVLLF
                     FRKPGWQPLLALAAAFGLVDVFCMAQVYIHASVATWQHSNTLALFFGTSGIIGSVVIA
                     LAYLRNAGAAMRCAVVVVALMVLIRLIMQPLWLADINAVDTTVVTFPHHPLQALAQLR
                     DIYLLGWCVSAAGMLCFAAGGLRNARGTLVAGSVLLLIGEIMLRYVFFSIG"
     gene            12416..13279
                     /locus_tag="OPV72_001904"
     CDS             12416..13279
                     /locus_tag="OPV72_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HCR9914217.1"
                     /translation="MVNLTIDPAVDVTQACVRRRFRFSSCRACTDVCPAQVFSLAQGQ
                     VSIDTTRCIACGDCLFVCPVDAITDIKPVKRFVQGDTLVGPFSLQAPTVDELLLWHSQ
                     YGIRFIDIAVERSAQWLMALAGLNLALRRYGEPGWSFKHVVGAEINASRRTLFHVPRD
                     AITPCAVEPGKRRLRQAFSAFSECVPEISPQECRMCGACWRSCPENVIQFDDDTLTIA
                     AARCTGCGGCAAVCPHQALRLRFDVEPASTRHSAVHTLTCESCKRTFHALTPEHTHCV
                     LCQSPEFAVRL"
     gene            13400..13831
                     /gene="ndk"
                     /locus_tag="OPV72_001905"
     CDS             13400..13831
                     /gene="ndk"
                     /locus_tag="OPV72_001905"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000963848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HCR9914218.1"
                     /translation="MAIERTFSIIKPNAVAKNVIGSIFARFEAAGFKIVGTKMLHLTV
                     EQARGFYAEHDGKPFFDGLVEFMTSGPIVVSVLESENAVQRHRDLLGATNPANALAGT
                     LRADYADSLTENGTHGSDSLESAQREIAFFFGEGEVCPRTR"
     gene            14038..15204
                     /gene="trmG/rlmN"
                     /locus_tag="OPV72_001906"
     CDS             14038..15204
                     /gene="trmG/rlmN"
                     /locus_tag="OPV72_001906"
                     /EC_number="2.1.1.-"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tRNA
                     (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA
                     large subunit methyltransferase RlmN"
                     /protein_id="HCR9914219.1"
                     /translation="MSEQIVTPESSTPVVLNNETKINLLDLNRQQMREFFKNLGEKPF
                     RADQVMKWMYHYCCDNFDEMTDINKVLRGKLKEVAEIRAPEVVEEQRSSDGTIKWAIA
                     VGDQRVETVYIPEDDRATLCVSSQVGCALECKFCSTAQQGFNRNLRVSEIIGQVWRAA
                     KIVGAAKVTGQRPITNVVMMGMGEPLLNLTNVVPAMEIMLDDFGFGLSKRRVTLSTSG
                     VVPALDKLGDMIDVALAISLHAPNDTIRDEIVLINKKYNIETFLGAVRRYLEKSNANQ
                     GRVTIEYVMLDHVNDGTEHAHQLAELLKETPCKINLIPWNPFPGAPYGRSSNSRIDRF
                     SKVLMSYGFTTIVRKTRGDDIDAACGQLAGDVIDRTKRTLRKRMQGEVIDIKAI"
     gene            15498..16472
                     /gene="rodZ"
                     /locus_tag="OPV72_001907"
     CDS             15498..16472
                     /gene="rodZ"
                     /locus_tag="OPV72_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoskeleton protein RodZ"
                     /protein_id="HCR9914220.1"
                     /translation="MNTEATHDQNEAQTTGVRLRNAREQLGLSQQAVAERLCLKVSTV
                     RDIEEDKAPSDLASTFLRGYIRSYARLVHVPEEELLPGLEKQAPLRAAKVAPMQSFSL
                     GKRRKKRDGWLMSFTWLVLFVVVGLTGAWWWQNHKAQQEEITTMADQSTAELNADKDS
                     GQSVPLDTSAATSQDTTPAQTAPAPATPVDSTAATQNTVVAPSQANVDTAATSAAPAA
                     TETPSALPTSQAGVAAPAADPNALVMNFTADCWLEVTDATGKKLFSGMQRKDGNLNLT
                     GQAPYKLKIGAPAAVQIQYQGKPVDLSRFIRTNQVARLTLNAEPTPAQ"
     gene            16499..17617
                     /gene="ispG"
                     /locus_tag="OPV72_001908"
                     /gene_synonym="gcpE"
     CDS             16499..17617
                     /gene="ispG"
                     /locus_tag="OPV72_001908"
                     /gene_synonym="gcpE"
                     /EC_number="1.17.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="HCR9914221.1"
                     /translation="MHNQAPIQRRKSTRIYVGNVPIGDGAPIAVQSMTNTRTTDVEAT
                     VNQIKALERVGADIVRVSVPTMDAAEAFKLIKQQVSVPLVADIHFDYRIALKVAEYGV
                     DCLRINPGNIGNEERIRMVVDCARDKNIPIRIGVNAGSLEKDLQEKYGEPTPQALLES
                     AMRHVDHLDRLNFDQFKVSVKASDVFLAVESYRLLAKQIDQPLHLGITEAGGARSGAV
                     KSAIGLGLLLSEGIGDTLRVSLAADPVEEIKVGFDILKSLRIRARGINFIACPTCSRQ
                     EFDVIGTVNALEQRLEDIITPMDVSIIGCVVNGPGEALVSTLGVTGGNKKSGLYEDGV
                     RKDRLDNDDMIAQLESRIRAKVSQLDEARRIDVLQVEK"
     gene            17728..19002
                     /gene="hisS"
                     /locus_tag="OPV72_001909"
     CDS             17728..19002
                     /gene="hisS"
                     /locus_tag="OPV72_001909"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HCR9914222.1"
                     /translation="MAKNIQAIRGMNDYLPGETAIWQRIEGTLKNVLGSYGYSEIRLP
                     IVEQTPLFKRAIGEVTDVVEKEMYTFEDRNGDSLTLRPEGTAGCVRAGIEHGLLYNQE
                     QRLWYIGPMFRHERPQKGRYRQFHQLGAEVFGLQGPDIDAELIMLTARWWRALGISEH
                     VSLELNSIGSLEARANYRDALVAFLEQHQETLDEDCKRRMYTNPLRVLDSKNPDVQAL
                     LNDAPVLGDYLDDDSREHFAGLCKLLDAAGIAYTVNQRLVRGLDYYNRTVFEWVTNSL
                     GSQGTVCAGGRYDGLVEQLGGRATPAVGFAMGLERLVLLVQAVNPEFIASPVVDIYLV
                     AAGAQTQSAAMTLAERLRDEMPGVKLMTNHGGGNFKKQFARADKWGARIALVLGESEV
                     ADGTVVVKDLRSGEQTAVAQDSVAAHLRTLLG"
     gene            19016..19636
                     /locus_tag="OPV72_001910"
     CDS             19016..19636
                     /locus_tag="OPV72_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfgM family protein"
                     /protein_id="HCR9914223.1"
                     /translation="MEIYENEHDQVDAIKRFFAENGKALAVGVILGVGALVGWRYWSS
                     HQTESARAASLAYQNAVTAVSADKPDSIPAAEKFAAENKNTYGALASMELAQQFVDKN
                     ELKKAEAQLQQGLAATSDENLKAVINLRLARVQLQLKQADAALKTLDAVKGEGWTAIV
                     ADLRGEALLSKGDKKGARSAWEAGVNSDASPALSEMMQMKINNLSI"
     gene            19647..20825
                     /gene="bamB"
                     /locus_tag="OPV72_001911"
     CDS             19647..20825
                     /gene="bamB"
                     /locus_tag="OPV72_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamB"
                     /protein_id="HCR9914224.1"
                     /translation="MQLRKLLLPGLLSVTLLSGCSLFSGEEDVVKMSPLPQVENQFTP
                     TTVWSTSVGNGIGEFYSNLHPVMADNVVYAADRAGVVKALNADDGKEIWSVNLGEKDG
                     WFSRSSALLSGGVTVAGGHVYIGSEKAEVYALNTSDGTTAWQTKVAGEALSRPVVSDG
                     IVLIHTSNGQLQALNQADGAIKWTVNLDMPSLSLRGESAPATAFGAAIVGGDNGRVSA
                     VLMQQGQMIWQQRISQATGPTEIDRLSDVDTTPVVVNGVVYALAYNGNLTALDLRSGQ
                     IMWKRELGSVNDFIVDGDRIYLVDQNDRVLALTTDGGVTLWTQSDLLHRLLTSPVLYN
                     GDLVVGDSEGYLHWINVDDGRFVAQQKVDSSGFLTEPTVADGKLLIQAKDGTVYAITR
                     "
     gene            20944..22416
                     /gene="der"
                     /locus_tag="OPV72_001912"
     CDS             20944..22416
                     /gene="der"
                     /locus_tag="OPV72_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HCR9914225.1"
                     /translation="MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGR
                     AEVEGREFICIDTGGIDGTEDGVETRMAEQSLLAIEEADVVLFMVDARAGLMPADEAI
                     AKHLRSREKPTFLVANKTDGLDPDQAVVDFYSLGLGEIYPIAASHGRGVLSLLEHVLL
                     PWMDDVAPQEEVDEDAEYWAQFEAEQNGEEAPEDDFDPQSLPIKLAIVGRPNVGKSTL
                     TNRILGEERVVVYDMPGTTRDSIYIPMERDEREYVLIDTAGVRKRGKITDAVEKFSVI
                     KTLQAIEDANVVLLVIDAREGISDQDLSLLGFILNSGRSLVIVVNKWDGLSQEVKEQV
                     KETLDFRLGFIDFARVHFISALHGSGVGNLFESVREAYDSSTRRVSTAMLTRIMTMAV
                     EDHQPPLVRGRRVKLKYAHTGGYNPPIVVIHGNQVKDLPDSYKRYLMNYFRKSLEVMG
                     TPIRIQFKEGENPYANKRNTLTPTQMRKRKRLMKHIKKSK"
     gene            22505..22726
                     /locus_tag="OPV72_001913"
     CDS             22505..22726
                     /locus_tag="OPV72_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HCR9914226.1"
                     /translation="MEIICPVCHHALERNGDTAHCETCAKDFSLQALCPDCRQPLQVL
                     KACGAVDYFCQNGHGLISKKRVNFVISDQ"
BASE COUNT         5056 a         5997 c         6798 g         4984 t
ORIGIN      
        1 ttaccgataa aaaataggat tttattaaga gaaaataatg cccgtttgca ggacagtgga
       61 aaagagcgga ataaaaacaa tgtctgtaga tcgttttaca tcagcctgaa cggtaggccg
      121 gataagcgtg agcaccatcc ggcatggcgg atattaagcg ggttcaaccg gtaaatcggt
      181 acgcgcgccc cattcgctcc acgcgccgtc gtaaagcgtg acgtcaggca catccagcgt
      241 ggcgagtgcc agcaccacga ccgcggccgt cacgccggaa ccgcaactgg cgataatcgg
      301 tctgtcgaaa ctcacgccgt ggctgaaaaa aacctcattc agttcgtcag tggtctttaa
      361 ttcgccctca tacaccagtt ccgtccacgg gacgtttagc gcgccaggaa tgtgtccgcg
      421 tctcagtccc ggacgcggtt catcagcctg agcgttaaaa cgcgccgccg gacgcgcgtc
      481 gacgatttgc gcggtttttt catggcttgc cagcaatacg tcggtgagac gcaccacggc
      541 ttgcggcgtg aatttcgcct caaactcgcc tccttcatgc gcttcttcgc cttcgcgcaa
      601 tagccattcg tcgcgctgcc agcccgccag tccgcccgcc agaatggaca ctttctcggc
      661 accgaacgtg cgcagcatcc accatgctcg cggagcggag aacagattgc cttcatcgta
      721 tatgaccagg tgtttatcct ggcgaacacc cagttcacgc atggccaccg caaacgcttc
      781 cgggcgcggc atcatatgcg gcagcggcga tgcgcgatcg gaaagcgctt caatatcaaa
      841 aaacagcgcg ccgggaatat gtccggcgcg atattcgccc gccatatcac gatgttcctg
      901 tcctggtggc gccatacggg cgtcaagaat ctgtatttcc ggatcatcaa tatgttcggc
      961 aagccagtcg gcggcgacaa aaaaggcggt ggtcatgggc atctccattg ttacctgatt
     1021 atggtcaaat tgtcggacgt ttcccgaaaa gggacaagta gaagaggctg ttttggctgg
     1081 cgaaaccaca tttctgcgta aaattttcgc gtcatcacag taatacggac ttacacaata
     1141 aaatttctcg cgcataatat ctcatcaacc gttgctgaca ggccgttaag gccagggatg
     1201 aaagatgaaa catttacgcg tggtggcctg catgatcatg ctggcgctgg cgggatgcga
     1261 taacaacgat aaaaccgccc cgacgactaa aagcgaagcg ccagccgtag cgcagccctc
     1321 gcccgcgcaa gacccgtcac agctacaaaa gctggcgcag caaagccagg gcaaagcgct
     1381 cacgctatta gacgcctccg aagcgcagct cgacggcgcg gcgacgctgg tgctgacgtt
     1441 ttcaattcct ttagatcctg aacaggattt ctcccgtgtg gttcacgtgg ttgataagaa
     1501 aagcggcagc gttgacggcg catgggagct ggcgccaaat ttaaaagagc taaggttacg
     1561 tcatctggaa cctgagcgcg tgctggtggt cacggttgat cccgccgtta aagcgctgaa
     1621 taacgccacc ttcggcaagt cttatgaaaa aacgattacc acgcgtgatg tccagcccag
     1681 cgtcggcttt gccagccggg gatcgctgct accggggaaa atagcggaag gactgccggt
     1741 catggcgctt aacgtcaacc acgttgatgt gaactttttc cgcgttaagc ccggatcgct
     1801 ggcgtcgttt gtcagccagt gggagtaccg tagttccctc tctaactggg aatccgacaa
     1861 tctgctgaaa atggcggatc tggtttatac cggtcgtttt gatcttaatc cggcgcgtaa
     1921 tacgcgtgag aaactgctgc tgccattaag cgatattaag ccgctgcaac aggcgggcgt
     1981 atatgtggcg gtaatgaatc aggctggaca ctacaactat agtaatgccg ctacgttgtt
     2041 tacccttagc gatatcggcg tgtccgcgca ccgttaccat agtcggctgg atatctttac
     2101 gcaaagcctg gaaaacggcg cggcgcagtc gggaattgag atcgttcttc tgaatgataa
     2161 agggcagacg ctggcgcagg cgacgagcga cgcgcaggga catgtgcaac tggaggctga
     2221 taaagcggcg gcgctattac tggcgcgtaa agaggggcag accacgctgc tcgatctcac
     2281 gcttccggct ctggatctgt cggagtttaa tgtcgctggc gcgcccggct acagcaagca
     2341 gttctttatg ttcggcccac gcgatctcta ccgaccgggc gaaacggtta tcctcaacgg
     2401 attactgcgc gatagcgacg gtaaaacgct gcccgatcaa cccgttaagc tggaagtggt
     2461 aaaaccagac ggacaagtga tgcgtaccgt cgtcagccag ccggaaaacg gactataccg
     2521 tttgaattat ccgctggata tcaacgcgcc gaccggcttg tggcatgtcc gcgccaacac
     2581 cggcgataat ttgctgcgga gttgggattt ccacgtggaa gactttatgc cggagcggat
     2641 ggcgctcaac ctgacggcgc aaaaaacacc gctggcgcct gcggatgagg tgaaattctc
     2701 cgttgtcggc tattacttgt atggcgcccc tgctaacggc aataccctgc aagggcaact
     2761 tttcctgcgt ccgctgcgcg acgctgtcgc ggcgttgcct ggcttccagt tcggcaatat
     2821 tgccgaagag aatctttcgc gcagcctgga cgaagttcaa ctgacgttgg ataaaggcgg
     2881 acgtggtgaa gtgagtgctg ccagccagtg gcaagaagcg cattcgccgt tgcaggtaat
     2941 tctacaggcc agcctgctgg agtctggcgg tcgtccggtc actcgtcgcg tagagcaggc
     3001 gatttggcct gccgatacgt taccgggaat tcgtccacag ttcgccgcca aagcggtata
     3061 cgactaccgt acggatacca ccgttaatca accgattgtc gacgaagaca gcaacgccgc
     3121 attcgatatt gtttacgcca acgcgcaggg cgagaaaaaa gcggtgtccg gtttacaggt
     3181 gcggctcatc cgcgagcgtc gcgactatta ctggaactgg tcggaaagcg aaggctggca
     3241 gtcgcagttt gatcaaaaag atctggtgga gggcgagcag acgctggatc tgaacgcgga
     3301 tgaaaccgga aaagtcagct tcccggtgga atggggcgcg taccgtctgg aggtcaaagc
     3361 gccgaatgag acggtcagca gcgttcgttt ctgggccggc tatagctggc aggataacag
     3421 cgacggtagc ggcgcggcgc gtccggatcg cgtcaccctc aaactggata aagcgaatta
     3481 tcgtccaggc gacaccatga aattgcatat cgccgcgccg gtcgccggta aaggttatgc
     3541 catggtggag tccagcgatg gtccgctgtg gtggcaggcg atcgacgtgc cggcgcaggg
     3601 gctggagctc acgattccgg tggataaaac ctggaatcgc cacgatctct atctcagtac
     3661 gctggtggtg cgtcccggcg ataaatctcg ttccgcgacg ccaaaacgcg ccgtggggtt
     3721 actacatcta ccgctggggg atgacaaccg ccgcctcgat ctggcgctgg aaagcccggc
     3781 taaaatgcgc ccgaatcagc cgctcaccgt cagggtgaaa gccagcgtta aacacggcga
     3841 aatgccaaaa cagatcaacg tgctggtctc cgcggtcgat agcggtgtat tgaatatcac
     3901 cgattacgcg acgccggacc cgtggcaggc gttcttcggt caaaaacgct acggtgcgga
     3961 tatctacgat atttacggcc aggtcattga agggcagggg cggctggcgg cgttgcgttt
     4021 tggcggcgat ggcgacgacc ttacgcgcgg cggaaaaccg ccggtaaacc atgccaatat
     4081 catcgcgcag caggcgcagc cgatcacgct caatgagcag ggcgaagggg tcgtaacgct
     4141 gccgattggc gactttaacg gcgaactgcg ggttatggcg caggcatgga cagcggacga
     4201 ttttggtcgc ggcgaaagca aagtcgttgt cgccgcgcca gtgattgccg agctgaatat
     4261 gccgcgtttt ctggcgggag gggatgtttc gcgactggtg ctggacgtca ccaatctgac
     4321 cgaccgcccg cagacgctga atattgcgct cgccgccagt gggttactgg aactgcttag
     4381 tcaacagccg caaccggtca acctggcgcc gggcgtgcgc accaccttat tcgttccggt
     4441 acgcgcgctg gaaggttttg gcgaaggcga aatccaggcg accattagcg gtctgaatct
     4501 gccgggagaa accctcggcg cgcagcataa gcagtggcaa atcggcgtgc gtccggcctg
     4561 gcctgcccaa acggtaaata gcggcattgc gctggcgccg ggagagagct ggcatgtacc
     4621 agagcagcat ctggcaaacg tctcgccagc cacgttacag ggacaactgc tgttaagcgg
     4681 aaaaccgccg ctcaatctgg cgcgctacat tcgcgagctg aaagcatatc cgtacgggtg
     4741 cctggaacaa accaccagcg ggttattccc ggcgctgtat accaatgccg ctcaattgca
     4801 gtcgctcggt attaccggcg atagcgatga aaaacggcgc gccgcggtgg atatcggcat
     4861 ctcccgcata ctacagatgc agcgtgataa cggcggtttt gcgctatggg atgaaaatgg
     4921 ggcggaagag ccctggctaa cggcctacgc gatggatttc ctcattcgcg cgggcgagca
     4981 gggatatagc gtcccgccgg aggccattaa ccggggcaat gagcgactgc tgcgctatct
     5041 gcaggatccc ggtacgatgc tgattcgtta tagcgataat acccaggcca gtacttttgc
     5101 cgctcaggct tacgccgcgc tggtactggc gcgtcagcag aaagcgccgc tcggcgcgct
     5161 gcgcgaaatc tgggagcgcc gtagtcaggc ggcttcagga ctgccgctga tgcaattggg
     5221 catcgcgtta aacacgatgg gtgatgccag acgcggcgaa gaggccatta cgctggctct
     5281 gaatacgccg cgtcaggacg aacggcaatg gatagcggat tacggcagtt ctctgcgcga
     5341 taacgctctg atgttgtcgt tactggaaga gaacaacctc agaccggacg cgcaaaacgc
     5401 gctattaagc tcgctttctg agcaggcctt cggtcagcgc tggctctcta cccaggagaa
     5461 caatgccttg ttcctcgccg cgcattcgcg acaggccagc gcgggcgcct ggcaggcgca
     5521 gacctcgtta gaggcgcagc cgctgtcggg cgacaaggcg ctgacccgta atctggatgc
     5581 tgatcagctg gccgcccttg aggtgacgaa caccggtagc cagccgctat ggctgcgtct
     5641 ggatagcagc ggctatccct catctgcgcc tgagcctgcc agcaacgttt tgcagattga
     5701 acgacaaata ctggggaccg atggtcagcg caaatcgctg tcctcgttgc gtagcggcga
     5761 actggtgctg gtctggttaa cggtagtggc cgatcgcaat gtgccggatg cgctggtggt
     5821 ggacctgctc ccggccgggc tggagctgga aaaccagaat ctggctgaca gcagcgccag
     5881 cctgccggag agcggtagcg aagtgcaaaa tctgcttaat cagatgcagc aggcggatat
     5941 tcagtatatg gaattccgcg acgatcggtt tgtggctgcc gtcgttgtca atgagggcca
     6001 gcccgtgacg ctggtctacc tggcgcgcgc ggtaacgccg gggacgtacc agcttgcgca
     6061 accgcaggtg gaatcgatgt acgcgcctca gtggcgggca accggcgcga gcgagggact
     6121 gctgattgtg acgccttaaa tgaacggttg gcgtggtaaa cgtggccgct ggctgtggct
     6181 ggcgggcgcg ccgcttttta ttttcctggc gttatgggca gcggataaac tctggccgct
     6241 gccgctcaat gaggtccatc ctgcgcgggt cgtggtcgcc catgacggta cgccgctgtg
     6301 gcgctttgcc gacgccgggg ggatctggcg ttatccggtg acgattgaag aggtctctcc
     6361 ccgttacctg gaggccttaa tcaattacga agatcgctgg ttctggcagc accctggcgt
     6421 taaccctttt tccgtcgcgc gcgcggcatg gcaggatctt accgccgggc gcgttatttc
     6481 cggcggcagt acgctgacta tgcaggtggc gagacttctg gacccgcatt cgcgcacgtt
     6541 cggcggtaaa atccgccagc tttggcgcgc cctccagctt gaatggcatt tgtccaagcg
     6601 cgatatcctg acgttgtacc tgaaccgcgc gccgttcggc ggcacgctac agggtattgg
     6661 cgctgcaagc tgggcctact tcggcaagcc gcccgcgcgc ctgagctacg ctgacgcggc
     6721 gctgctggcc gtattgccgc aggcgccgag ccggttacgc cccgaccgat ggcctacgag
     6781 agccgaagcg gcacggaata aagtgctgga tcggatggcg gagcagggcg tctggcctgc
     6841 cgaaacggta cgcgagtcgc gtgaagagcc ggtctggctg gcgccgcgtc aaatgccgca
     6901 actggcgccg ctttttgccc gaatgatgtt gagtaaaagc cggagcgaca aaattgtgac
     6961 cacgctggac gccgggttgc agcggcaact ggaagatctg gcgcgggcat ggaaagggcg
     7021 gctgcctgca cgcagttcat tggcgatgat cgtcgtcgat cataccgata tgagcgtgcg
     7081 cggctgggta ggatcggtag accttaatga cgacagccgt tttggtcatg tcgacatggt
     7141 aacggcgatc cgatcgccgg gatcggtact caaacccttt gtgtatggtc tggcgctgga
     7201 tgacggcttg atccatcccg catcactatt acaggacgtt ccgcgccgca ccggagatta
     7261 ccgcccggga aacttcgata gcggatttca cggcccggtt agcatgagcg acgcgctggt
     7321 acgctcgctg aatctgcctg ccgttcaggt gcttgaagcc tatgggccga aacgatttgc
     7381 ggcaaaactg cgtaacgtcg gcctgccgct atatttgcct gctggcgcgg cgcccaatct
     7441 ttcgctgatt ctgggcggcg cgggcgcgcg gcttgacgag atggcggcgg catacagcgc
     7501 gttcgctcgt catgggaaag cggcgaaact acggttacag ccggacgatc cgctgtcgga
     7561 aagaccatta atgtcgccgg gagcggcgtg gatcattcga cggattatgg cggatgaagc
     7621 gcaacccttg ccggataacg cgctgccgcg cattgtgccg ttggcgtgga aaaccggcac
     7681 cagctacggc tatcgcgatg cgtgggctat tggcgttaac gcgcgctata tcatcggcat
     7741 ctggacaggc agacccgacg gcacgcctgt ggtggggcaa tttggttttg ccagcgcggt
     7801 gccattgctt aaccaggtca ataatctgtt actggcgcat acgggacgcc tgccggaaga
     7861 tccgcgtccg cagacggtaa gccgcggcgt catttgctgg ccgggcggac agactctgcc
     7921 tgccgggaac agcaactgtc gccgccgact ggcgacatgg ctgcttgacg acagccagcc
     7981 gcccacgctg ctgttacctg agcaggaaga catcaacggt attcgtttcc cggtctggct
     8041 ggatgatacg gggcggcgtg tcgctgccga ctgtccgcag gcgcgtgcgc atacgtttat
     8101 cgtctggccg cggccgctgg agccgtggct gccgcctgcg gaaagacgta gcgcccgctt
     8161 gcccgcggcg tccgaccact gtccgccgct acagggcaat gatgccgcgc cgttaatgct
     8221 gtcaggagtg agggatggcg cggtgatcag gcaattgcca ggccaggaaa acgtcacgct
     8281 gcccgtctcg actaccggcg gcaaagggcg tcgctggtgg tttttaaatg gcgaacctgt
     8341 taatggcgaa aataatcgcc tttctttatt actcaatatc gctggacgtt atcaacttgt
     8401 cgtaatggat gagtccggtc aggttgcagc ggttaatttt gaattaatac gttaaccatt
     8461 ctccaaaata gattatcaat tccttttaat ttaagcttaa tgataattgt taattattac
     8521 tggatcatac ataaccggag agcttgataa atatcaagag aaccaacgca taaaaacgtg
     8581 agaatgggtt tttatttgac gagtcggatc atgaaaaata taaaaagcca gggaaatggc
     8641 gaacagcccg ctatttctcg ccgccatttt atccaggcca gctccgcgct tattgagtta
     8701 ccgtttgtct cctcgccagc taccgctcag gcgcgcgctg tgacggcaac tgaaaacagg
     8761 cctgcggaaa aagtcgttca gacatgcagc acttttgact gcgggggcaa atgcgatatt
     8821 cgggcgcatg tcagtgacgg tatcgtgacg cgaatttcaa cgcgaccgga taacgcgctg
     8881 gatgcgcaaa tgccggtgat gcgtgcctgt gttcgtggac gagcataccg taaatttgtt
     8941 tatcatcctg acagacttaa atatcccatg aagcgcgtag gaaaacgcgg tgaaggaaag
     9001 ttcgagcgaa tttcctggga tgaagcgaca accttaatcg ccgataattt aaaatcgatt
     9061 actgaaaaat atggcccggc ttcgcgctat gttcatgttg gtaccgccgt ttccggcggc
     9121 accttttccg gcgataaaat ggcgcgtcgc ctgctgaatc ttaccggcgg ctatctcgaa
     9181 agctaccatt cggtgagtat gggcaacacg gtggccgcga cgccttatac ttacggcatt
     9241 gccgccagcg gcagttcgct ggatacgctt ttggacacca aactggtgat tctgtggggc
     9301 cataacccga cggagaccat ttttggtcat accaactatt tcttgcagaa gatgaagcag
     9361 aacggtacgc ggtttatcgt ggttgatccg cgctattccg acaccgtttc gtcgctggcg
     9421 gatcagtgga tcccgctgct gcccaccacc gacaatgcgc tgatggacgc gatgatgtac
     9481 gtcatcatca gcgagaatct gtacgatcgt gcatttattg cgcgctacgc tatcggtttt
     9541 gacgaagact caatgccgga aggcgtaccg gctaacgaat cgctggtggc atatctgacc
     9601 ggcgccaaag acggtgtcgt taagtctccc gagtgggcgg aaaagatcac ccatgtgccg
     9661 gcgcaaacca ttcgccagtt agcgcgtgat tacgcgaaga ccaaacctgc cgcgttgatt
     9721 caggggcggg gccacagcgc cacaactgcg gcgagcgcac cgcgcgcggc tcgactctac
     9781 tggcgaccat taccggtaat gtcggcatca aaggcggttg ggctgcgggt tacggcggct
     9841 gcgctaaccg taaatttgcc gcgggtccgg agatgccgga taacccggta aaagccaaaa
     9901 tttcggtgat gaactgggtg caggccgcag acgacgccag caaagtgacg ccggatatgg
     9961 ggctgaaaga tgccgataag ctggacagta acatccgtat tctgttctcg ctggccggga
    10021 actatctggc gaatcagaac cccgatctgc accaggcggt acgcgtactg gaggatgaat
    10081 caaagatcca gtttattgtc gccagcgatc tgtttatgac gccgagcgcg aaatacgccg
    10141 atctactgct gccggaaacc agctttatgg aacgttggaa catcggtgaa acttggggca
    10201 cggcaagcta cctgatactc tctgaaaaac tgatcgagcc tgaatttgag cgtcgctccg
    10261 actacgactg gctacgtgag gtggcggcga aattaggcat tgagaatgaa tttagccagg
    10321 ggcgcgatga gaaagcgtgg attgaacaca tctgggaaca gacgcgcctg gcgatgccgg
    10381 acgaaaatct gccggatttt gccacactgc aaaagacccg tcagcatctg ttcaaaagcg
    10441 cgccatttat cgcctttgaa gacaatattc gcgatccgga caatcatccg ttcccgacgc
    10501 cgtcagggaa aatagaggtc ttctcgaagc gcctgtacga catgcagcat ccggaaatcc
    10561 cggcgttgtc gcactacgtt cccgcgcatg aaggcccgga ggatgcgctg gtgaaagatt
    10621 ttccgctcca gttaattacg tggaaaggaa aaaaccgcgc caactcaacg caatacgcta
    10681 acccgtggct gattgaagtg cagcagcaga cattgtggat caacccgcag gatgcgcaaa
    10741 cgcgcggcat tacgcatggc gacatggtgc gcattcataa ctcacgcgga atttgcgaaa
    10801 tcccggcgga agtgacgccg cgcattattc ccggcgttgt cgcgatgcag gctggcgcct
    10861 ggtggcagcc ggatgagaac ggtattgata aaggcggctg cgcgaacgtc ctcagctcgg
    10921 cccgtattac cgccctggcg aagggaaatt cacatcaaac catgctggtg gaggtggcaa
    10981 aagcatgagc cagtttacac attacccgcc ggtgagcgat aaacaactgg gatttttcat
    11041 cgactcctca cgctgctccg gttgtaaagc ctgccaggtg gcctgcaaag acaaaaacaa
    11101 tctggaagta ggccgtcgtt tccgccgcgt ctatgaagtc aagggcggaa gtttcatccc
    11161 gaccgggcag ggcagggtca gcaataacgt atttgcttat acgctttcta tttcctgcaa
    11221 ccactgtgcg gatcctgtct gcaccaaaaa ttgcccgact accgctatgc ataaacgccc
    11281 aggtgacggc attgtgcgcg ttgataccga caaatgcgtc ggctgtggct attgcgcctg
    11341 gtcctgccct tatggcgcgc cgcagcttaa cgagcagacc ggccaaatgt ccaagtgcga
    11401 catgtgcgtt gatttactgg cgaaaggtga atcgcccggc tgtgtcgcga cctgtccgct
    11461 ggaggccatc aagtttggcc cgattgatga actgcgcgcg aagtacggta gcgtatgcga
    11521 cgttaacggg ctgccagatt catccataac caaacctaat ctggttgtca aagcgcatca
    11581 gggcgcagaa aaagagggta aacgccatgc atgagttacc gctgctgatt tttacgctct
    11641 gtttgcaagg gtccgtgggc gtgactctgt ggctggcgct gggccgtcag tacgccgtag
    11701 agggacgcgt acctgcgcgc ggcgcgcttc ccgcgatggc gggggcgttt gtactggcct
    11761 gcgtggggct gcttgcttca gcgctgcaca tgggctatcc cctgaatgcg ctaaacgcgt
    11821 tacgtcatgt cgccagttcg tggctgagtc gcgaaatcgt ctttgccagc ctttatctgg
    11881 cggcgctggg gctgggggtt gtgctgctgt ttttccgaaa gcctggctgg cagccgctgc
    11941 tggcgctggc ggcagcgttc gggctggtgg atgtattctg catggcgcag gtttatatcc
    12001 atgcctcggt ggcgacctgg cagcatagca acacgctggc gctgttcttt ggcacgtcag
    12061 gcattatcgg ctcggtagtc attgcgctgg cttatctgcg caacgctggc gccgcaatgc
    12121 gctgcgctgt ggtggtggtc gcactgatgg tgctgattcg cctgatcatg cagccgctat
    12181 ggttggcgga tattaatgca gtggatacga cggtcgtcac tttcccgcat catccgctac
    12241 aggcgctggc gcagttgcgc gacatctatc ttctcggctg gtgtgtctca gcggcgggaa
    12301 tgctctgctt tgccgcaggc ggtctgcgaa acgccagagg gacgctggtg gcgggcagcg
    12361 tattgctgct tatcggcgag attatgctgc gctacgtctt ctttagtatt ggctgatggt
    12421 taacctgacg atcgatccgg cggtagacgt gacgcaggcc tgcgtccgtc gtcgctttcg
    12481 tttttcttcc tgccgcgctt gcactgatgt ttgtccggcg caggtgtttt cgctggcgca
    12541 ggggcaggtc agcatagata cgacgcgctg catagcctgt ggcgactgtc tgtttgtctg
    12601 tcctgttgac gccattaccg atatcaaacc ggttaaacgc tttgtgcagg gggatacgtt
    12661 ggtggggccg ttttcgctac aggcgccaac ggtcgatgaa ctgcttctct ggcacagcca
    12721 gtacggtatt cgctttattg atattgcggt ggagcgatcg gcgcagtggc tgatggcgtt
    12781 ggcggggcta aatttagcgc tgcgccgcta cggcgagccg ggctggtctt tcaaacacgt
    12841 tgtcggcgcg gaaattaatg cctcgcggcg cactctgttt catgttccgc gcgacgccat
    12901 taccccgtgc gccgtcgagc cggggaaacg gcgtctcaga caggcgtttt ccgcgttcag
    12961 cgaatgcgta cccgaaatca gtccgcaaga gtgcaggatg tgcggcgcct gctggcgaag
    13021 ctgcccggaa aacgttatcc agtttgacga cgacacgctg acgatagcgg cggcgcgttg
    13081 tacgggatgc ggcggctgtg cggcggtatg tccgcatcag gcgctgcggc tgcggtttga
    13141 cgtggaaccc gcctcaacgc ggcatagtgc ggtgcatacg ctcacctgcg aaagctgcaa
    13201 acgtactttc catgctctca cgcctgaaca cacgcactgc gtgctgtgtc agtcccctga
    13261 gtttgctgtg cgcctttaac ttttgttgct aatgctcatt ttattttaaa aaaatgttac
    13321 ctgcatccat aggcaattga tgggatgctc tttataatcc gcgcctgaca taacaacaga
    13381 acatatttca gaggtaaaca tggctattga acggactttt tccatcatta aacccaacgc
    13441 ggtggcaaaa aacgttattg gcagcatctt tgcgcgcttt gaagctgcag ggttcaaaat
    13501 tgttggcact aaaatgctgc acctgaccgt tgagcaggcg cgcggcttct atgctgagca
    13561 cgacggcaag ccgttctttg acggtctggt ggagttcatg acctctggcc ctatcgtggt
    13621 atccgtgctg gaaagtgaaa atgcggtaca gcgtcatcgc gatctgcttg gtgccaccaa
    13681 tccggcgaac gcgttggcgg ggacgctgcg tgctgattac gctgacagcc tgaccgaaaa
    13741 tggcacccac ggttcggatt cgctggaatc cgcgcagcgc gaaatcgcct ttttcttcgg
    13801 tgaaggcgaa gtgtgcccgc gcacccgtta atctccttcg tctttcacgc tgtaaatgcg
    13861 ttggcgataa attatcggtt caaatattat ttttgctaat gccgcgtgca gacgtggcat
    13921 ccttacgcca gaatttgtac aatgcagcgc ccccggacga gcagtaagct taccggggcg
    13981 tttctttttt caaccctcca ggggccataa cgtgtaataa cgaggccgga atagcatatg
    14041 tctgaacaaa ttgtcacacc tgaaagcagt accccggtag ttcttaacaa cgaaacaaaa
    14101 atcaacctgc tggatctaaa ccgtcagcag atgcgcgagt tttttaaaaa cttaggtgaa
    14161 aaacctttcc gcgccgatca ggtgatgaaa tggatgtatc actattgctg cgataatttt
    14221 gatgagatga ccgacatcaa caaagtgttg cgcggcaaat taaaagaggt cgcggaaatt
    14281 cgcgcgccgg aggtcgttga agagcagcgt tcttcagacg gcaccatcaa gtgggcgatt
    14341 gctgtcggcg atcagcgcgt tgaaacggtc tacatcccgg aggacgaccg cgctacgctg
    14401 tgtgtctctt cacaggtagg gtgcgcgctg gagtgcaaat tttgttcaac tgcgcagcag
    14461 ggctttaacc gcaacctgcg cgtatcggaa attatcggtc aggtctggcg tgcggcgaaa
    14521 atcgtcggcg cggccaaagt caccggccag cgtccgatca ccaacgtagt catgatggga
    14581 atgggcgagc cattgcttaa cctgaccaat gtcgtaccgg cgatggaaat tatgctcgat
    14641 gactttggtt tcggcctgtc caaacgtcgt gtcacgctct caacgtccgg cgtggtgcct
    14701 gcgctggata aactgggcga tatgatagac gtcgcgctgg ctatctcctt acatgcgccg
    14761 aatgacacta ttcgcgacga aatcgtcctg atcaacaaaa aatataatat cgaaacgttc
    14821 ctgggcgcgg ttcgccgcta tctggagaaa tccaacgcca atcaggggcg cgtgacgatt
    14881 gaatacgtga tgcttgacca cgttaacgac ggcactgaac acgcgcatca actggcggag
    14941 ctactaaaag agacgccttg taagattaat ctgattccgt ggaacccgtt ccctggcgcg
    15001 ccgtatggcc gcagctctaa cagccgtatc gatcgctttt ctaaagtttt gatgagttat
    15061 ggtttcacga ccatcgtacg caagacgcgt ggcgatgaca ttgatgcggc atgcggacag
    15121 ttggcaggcg atgtgattga ccggactaaa cgtactctgc gtaagcgtat gcagggagag
    15181 gtgattgaca tcaaggctat ttgatagcag ttgcgccacg gggcattcat tataccgtgg
    15241 cgcaatgtca gttgaataat gtctggcgtt gtacttgtct ggtcaataat aacggtgcgt
    15301 ttttgtcgac tttaaggcag tatgtaacga tgcaacaaga gtttaacctt gtgtcttaag
    15361 cggttttgtc atctgcggcc tgacaggctt atactgtctg actaaaggtt aactaacctg
    15421 atgtttcgcg gtgtgggcgg gcattacggc tcgtcggcgc ctgaatccta atttacacgt
    15481 acctgtagct gtagcgaatg aatactgaag ccacgcacga ccaaaatgaa gcacaaacca
    15541 ccggcgttcg tctgcgcaat gcccgtgaac aactcggact cagccagcag gctgtcgctg
    15601 agcgactttg cctgaaggtt tctacggtac gcgatattga agaagataag gcgccgtccg
    15661 atcttgcttc aaccttcctg cgcggatata tccgctcata tgcgcgtctg gtgcatgttc
    15721 cagaagagga actgctgccg gggctggaaa aacaagctcc gctgcgcgcc gctaaagtcg
    15781 ccccgatgca gagtttctca ttaggaaagc gtcgtaaaaa acgcgacggc tggttaatgt
    15841 cttttacctg gctggtactg tttgtggtcg tagggctgac cggcgcctgg tggtggcaga
    15901 accacaaggc gcagcaggaa gagatcacga caatggccga tcaaagcacg gctgaactga
    15961 acgcagataa agacagcggc caaagcgtac cgctggacac cagtgccgcg acaagccagg
    16021 atacgacgcc agcgcaaacg gctccggctc ctgcgacgcc ggttgattcg acggcggcaa
    16081 cgcaaaatac ggtagtcgcg ccttcgcagg cgaatgtcga tacggctgcg acatctgccg
    16141 cgccagcggc aacggaaacg ccgtccgcgc tgccgaccag tcaggctggc gtagcggcgc
    16201 ctgctgccga tccgaacgcg ctggtgatga attttaccgc tgactgttgg ctcgaagtca
    16261 ctgacgccac gggtaaaaaa ctgtttagcg gtatgcagcg taaagatggc aatttaaacc
    16321 taaccggtca ggcgccttat aaacttaaaa ttggcgcgcc ggccgcggtg cagatccagt
    16381 atcaaggaaa acctgtcgat ctgagccgct ttatcagaac taatcaggtt gcgcgtctga
    16441 cccttaatgc cgaaccgaca ccggcgcagt aacagacggg taacgcggga gatttttcat
    16501 gcataaccag gctccgattc aacgtagaaa atcgacacgt atttacgttg ggaatgtgcc
    16561 gattggcgat ggcgccccta tcgccgtcca gtcgatgact aacacgcgta ccactgacgt
    16621 ggaagcgacg gttaatcaga tcaaagcgct ggagcgcgtt ggcgcagata ttgttcgtgt
    16681 ttctgtaccg accatggacg ccgccgaagc gttcaagctt atcaaacagc aggttagcgt
    16741 cccgctggtt gccgatattc acttcgacta ccgcattgcg ctgaaagtag cggaatacgg
    16801 cgttgactgc ttgcgtatta accccggcaa tatcggtaac gaagaacgca ttcgcatggt
    16861 ggtggactgc gcgcgcgaca aaaacatccc tatccgtatc ggcgtaaatg ccggatcgct
    16921 ggaaaaagat ctgcaggaaa aatacggaga gccgacgccg caggcgctgc tggaatcagc
    16981 catgcgccat gtcgatcatc tcgatcgtct caactttgat cagttcaaag tgagcgtaaa
    17041 agcgtccgat gtattccttg ccgttgagtc ttatcgtttg ttggctaaac agatcgatca
    17101 gccgctgcat ctggggatca ccgaagcggg cggcgcgcgt agcggggcgg ttaagtcggc
    17161 gatcggttta ggtctgctgt tatcggaagg catcggcgac acgctgcgcg tatcgttggc
    17221 ggccgacccg gtggaagaga tcaaagtcgg tttcgatatc ctgaagtcgc tgcgtattcg
    17281 cgcgcgcggc atcaatttca tcgcctgccc gacctgttct cgtcaggagt tcgacgttat
    17341 cggcacggtg aacgcgctgg agcagcgtct ggaagatatc atcaccccga tggacgtctc
    17401 gatcatcggt tgtgtggtga acgggccggg cgaagcgctg gtatcgacgc tgggcgtgac
    17461 gggcggcaat aagaaaagcg gcctgtatga agacggcgtg cgtaaggaca gactcgataa
    17521 cgacgatatg atcgcgcagc ttgaatcccg tattcgcgcg aaagtaagtc aacttgatga
    17581 agcgcgtcgg attgacgtgc tgcaggttga aaaataagaa cgtgatggga agcggcgcgc
    17641 ttcccgtgta tgattgaacc cgcatggctc ccggttcgtt cggggaagcg ctgagggttc
    17701 atttttatat tcagaaagag aataaacgtg gcaaaaaaca ttcaagccat tcgcggcatg
    17761 aacgattatc tgcctggcga aaccgccatc tggcagcgca ttgaaggcac actcaaaaac
    17821 gtgctcggca gctacggtta cagtgaaatc cgcttgccga ttgtagagca gaccccgtta
    17881 ttcaaacgcg cgatcggtga agttactgac gtggttgaaa aagagatgta cacctttgag
    17941 gatcgcaacg gcgatagcct gacattgcgc cctgaaggta cggcgggctg tgtacgcgcc
    18001 ggcatcgaac atggtctcct gtacaatcag gaacagcgtt tgtggtatat cgggccgatg
    18061 ttccgtcatg agcgtccgca aaaaggccgc taccgtcagt tccatcagct aggcgccgaa
    18121 gtctttggct tacaaggccc ggatatcgac gcggaactga ttatgctgac cgcacgctgg
    18181 tggcgcgcgc tgggcatctc tgaacacgtt agcctggagc tgaactctat tggttcctta
    18241 gaggcgcgtg cgaactatcg cgatgcgctg gtcgcgttcc tcgaacagca tcaagagacg
    18301 ctggacgaag actgcaaacg ccgtatgtat accaatccgc tacgcgtgct ggattcaaaa
    18361 aatccggacg tgcaggcgct gctcaacgac gcgcctgttc tcggcgacta tctcgatgac
    18421 gattcacgcg agcactttgc cggcctgtgt aaattgctgg acgcggcggg gattgcctac
    18481 accgtcaacc agcgtctggt acgcggtctg gattactaca accgcaccgt atttgaatgg
    18541 gtaacaaaca gtctggggtc acaaggcacc gtctgtgcgg gtggtcgtta tgatggtctg
    18601 gtggaacaac tgggcggtcg cgctaccccg gcagtgggct ttgcgatggg cctggaacga
    18661 cttgttttgt tagttcaggc agttaatccg gaatttattg cctctcctgt tgtcgatata
    18721 tacctggtag ctgccggcgc acaaacgcag tctgcggcaa tgacgctggc ggagcggctg
    18781 cgcgatgaaa tgccaggcgt gaagctaatg acaaaccacg gcggcggcaa ctttaagaaa
    18841 cagtttgccc gcgccgataa gtggggcgcc cgtattgcac tggttcttgg cgaatctgaa
    18901 gtcgccgatg ggactgttgt agtgaaggat ttgcgctccg gtgagcaaac ggcagtggcg
    18961 caggacagcg tcgccgcgca tttgcgcact ttattgggct aaggagaagg acagcgtgga
    19021 aatttacgag aacgaacacg accaggtgga tgcgattaaa cgcttctttg ccgaaaacgg
    19081 caaagcgctg gctgtcggag tgattttagg ggttggcgcg ctggttggct ggcgttactg
    19141 gagcagccat cagacggagt ccgcgcgtgc tgcttctctg gcgtatcaaa atgcggtgac
    19201 ggcggtaagc gccgataagc cggatagcat tcccgccgct gaaaaattcg cggctgagaa
    19261 taaaaatacc tatggtgcgc tggcgtctat ggaactggcg cagcagtttg tggataagaa
    19321 tgaacttaaa aaagccgaag cccagttgca gcaggggttg gcggccacca gcgatgaaaa
    19381 tctcaaagcg gtgattaatc tgcgtctcgc tcgcgttcag ttacagctta agcaagctga
    19441 cgccgcgctg aaaactctgg atgccgttaa aggcgaagga tggacggcaa ttgtcgctga
    19501 tttgcgcggc gaagcgttgc tgagtaaggg tgataaaaaa ggcgcgcgca gcgcatggga
    19561 agcgggcgtc aatagcgatg cttctccggc gttgagcgaa atgatgcaga tgaaaatcaa
    19621 taatttgtcc atctgagagg gacccgatgc aattgcgtaa attacttctg ccagggttgc
    19681 tttccgttac cctgctcagc ggctgttcac tgtttagcgg cgaagaagat gtcgtcaaga
    19741 tgtctccatt accgcaggtt gaaaaccagt ttaccccgac cactgtctgg agcacctctg
    19801 tcggtaacgg aattggtgaa ttttattcta accttcatcc ggtaatggca gataacgtgg
    19861 tctatgcagc cgatcgcgcg ggcgtggtaa aagcgctcaa tgcggatgat ggcaaagaga
    19921 tctggtctgt gaatctgggc gagaaagacg gctggttctc tcgttcgtcc gcgctgttgt
    19981 ccggcggcgt cactgtcgcg ggcggtcacg tctatatcgg cagtgaaaag gccgaggttt
    20041 atgcgctgaa taccagcgac ggtaccacag catggcagac gaaggtcgca ggcgaagcgt
    20101 tgtctcgccc ggttgtcagt gatggaatcg tccttatcca taccagcaac ggtcagttgc
    20161 aggcgctaaa tcaggcggat ggcgccatta aatggacggt gaacctggat atgccttcgc
    20221 tgtcgctgcg cggcgaatct gcgccggcaa ccgcgttcgg cgcggctatc gttggtggtg
    20281 ataatggccg cgtcagcgcc gtgttgatgc aacaagggca gatgatttgg cagcagcgta
    20341 tctcccaggc cactggccca acggaaattg accgtctgag cgacgtcgat accacgccgg
    20401 ttgtggtaaa cggcgtcgtt tacgcgttgg cgtataatgg taacttaacg gcgctggatc
    20461 tgcgcagtgg tcagattatg tggaaacgcg agctggggtc ggtcaatgac tttatcgtcg
    20521 acggcgaccg tatctacctg gtcgatcaga acgatcgtgt gctggcgctg accactgacg
    20581 gcggcgtaac gctgtggacg caaagcgatc tgctgcaccg tttgctgacc tccccggtac
    20641 tgtataatgg tgatttagtc gtcggcgata gcgaaggtta tctgcactgg attaatgtcg
    20701 atgacgggcg ttttgtggcc caacaaaaag tagacagttc cggttttctg accgaaccga
    20761 cggtggcgga tggtaaactg ctcatccagg ccaaagacgg tacggtctac gcgattacgc
    20821 gttaatcgtc acggttgtgc gtttgaaaaa acggctcctg gtgtaggggc cgttttcctg
    20881 tttttaacaa cggcgtaaaa atgacgcgcg ttgtctgatg attttttaaa tgaggcttta
    20941 aacatggtac ctgtggtcgc gcttgtcggg cgccctaacg tcggaaaatc cacgctattt
    21001 aaccgtctga cccgcacccg agatgcgttg gttgcggatt tcccgggtct gactcgtgac
    21061 cgtaagtacg gtcgtgcgga ggttgaaggc cgcgagttta tctgtatcga caccggcggt
    21121 attgacggca ccgaagacgg cgtcgaaacg cggatggcgg aacagtcgct gctggcgatt
    21181 gaagaagcgg atgtggtgtt attcatggta gatgcgcgcg ctggtctgat gccggcggat
    21241 gaagcgattg ccaaacatct gcgctcccgt gaaaaaccga ccttcctggt ggcgaataaa
    21301 acggatggtc tcgatcccga tcaggcggtt gtcgattttt actcgctggg attaggcgaa
    21361 atttatccta tcgccgcctc acatggtcgc ggcgtattga gcctgctgga acatgtgctt
    21421 ctgccgtgga tggatgatgt cgcaccgcag gaagaagtgg atgaagacgc ggaatactgg
    21481 gcgcagttcg aggcggaaca aaatggcgaa gaagcgccgg aagatgattt tgacccgcaa
    21541 agcctgccga taaagctagc gattgtcggt cgcccgaacg taggtaagtc cacactcact
    21601 aaccgtattc tcggcgaaga gcgcgtggtg gtatacgaca tgccgggcac cactcgcgac
    21661 agtatttata tcccgatgga acgcgacgaa cgggaatatg tgctgattga cacggcgggg
    21721 gtgcgtaagc gcggaaaaat caccgatgcg gtagaaaagt tctcggtgat taaaacgtta
    21781 caggcgattg aagacgctaa cgtcgtactg ttggttatcg atgcgcgcga ggggatctct
    21841 gaccaggatt tgtctctgct gggctttatc ctcaatagtg ggcgctcact cgttatcgta
    21901 gtcaacaaat gggatggcct gagccaggaa gtcaaagagc aggtgaaaga gacgctggat
    21961 ttccgtctgg gctttattga ttttgcccgc gtgcacttta tctctgcgct gcacggcagc
    22021 ggtgtcggga acctgtttga gtccgtacgc gaggcttacg acagttccac tcgccgggtg
    22081 agcactgcga tgctgacccg tatcatgacg atggcggtgg aagatcatca gccgccgcta
    22141 gtgcgcggtc gccgtgtgaa gctgaaatat gcccacactg gcggctataa cccgccgatt
    22201 gtggttattc acggcaacca ggtaaaagat ctgccagact cctataagcg ctatctgatg
    22261 aactacttcc gcaagtcgtt ggaagtgatg ggtacgccga ttcgcattca gtttaaagaa
    22321 ggggagaacc cgtatgcgaa caagcgtaac acactgacgc caacgcaaat gcgcaaacgt
    22381 aagcgtctga tgaagcatat caagaaaagc aagtaatgct ttttcagtaa tattccaggc
    22441 ctgataagcg cagcgctatc aggcctttca agtaaaagcg agtcacgcgc ctgaggagaa
    22501 tgttatggaa ataatctgcc ctgtttgcca tcatgcgctg gagcgcaatg gcgatacagc
    22561 ccattgcgag acatgcgcta aggatttctc gttacaggca ctttgtcctg actgccgcca
    22621 gccgttacag gttttgaaag cctgcggcgc agtggactat ttttgccaga acggtcatgg
    22681 tttaatttca aaaaaacggg ttaatttcgt catttccgat caataaaacc actgtcgacg
    22741 ttgcgtcgca gagcagaggc gccgacgtct tatccggcta agggcaaaag cgttattcta
    22801 tactcccgta atatcagcat agtaccctgc ccggc
//
LOCUS       DAJVBX010000058        22525 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.058, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000058 DAJVBX010000000
VERSION     DAJVBX010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 22525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22525
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.058"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(279..416)
                     /locus_tag="OPV72_001914"
     CDS             complement(279..416)
                     /locus_tag="OPV72_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001454271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914227.1"
                     /translation="MRKARLTEHQNIAVIKLVEAGRAVKDICQEADISEVTDDIYGHW
                     V"
     gene            826..1138
                     /locus_tag="OPV72_001915"
                     /pseudo
     CDS             826..1138
                     /locus_tag="OPV72_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558297.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1267..2295)
                     /locus_tag="OPV72_001916"
     CDS             complement(1267..2295)
                     /locus_tag="OPV72_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence RhuM family protein"
                     /protein_id="HCR9914228.1"
                     /translation="MEDKYLTQSPAGEFIMFASGDGKVRVECRFESNTLWLSQGMICE
                     LYGKAKATISEHIKNIFADGELEENSVVRFYRTTASDGKNYQIQYFSLPLILAVGYRV
                     RSPRGTQFRQWATQTLQEYLIKGFVMDDERLKNPPVGSSAVPDYFDEMLERIRDIRAS
                     ERRVYLRVREIFALAADYQPSLKETTQFFQTIQNKLHFACTGYTAAELIHQRADACQP
                     HMGLTSYKGEEVRKCDVTVAKNYLTQDEVSELNRVVNMWLDFAEDQARRRQQVFLRDW
                     QDKLDQFLQFNDREVLQGAGKVSKKMADEKAQAEYSQFAEQQRRLKEAEGEKDIAALL
                     QWKTEPKK"
     gene            complement(2387..3217)
                     /locus_tag="OPV72_001917"
                     /pseudo
     CDS             complement(2387..3217)
                     /locus_tag="OPV72_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014227719.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4942 domain-containing protein"
     gene            complement(3366..3962)
                     /locus_tag="OPV72_001918"
     CDS             complement(3366..3962)
                     /locus_tag="OPV72_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02646 family protein"
                     /protein_id="HCR9914229.1"
                     /translation="MTLLLNEQYHLCCYSEIRADLRGLGYHIEHVENKSQQPGRTFDY
                     QNLAASALDSENGLPQLGINTFGGHVQGKNKSVDMAQFIHCHLPDCSRYFAYLSNGHV
                     VPSIDLTEQEAEYAQYTIDHLNLNSGFLQTERRNHWEELEQLFEEHIEKDWDLHQLLQ
                     LDLVPSPDHKLHEFFSITRQFFQQEAEQVLQSHAPALI"
     gene            4524..4868
                     /locus_tag="OPV72_001919"
     CDS             4524..4868
                     /locus_tag="OPV72_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914230.1"
                     /translation="MSYKYVGKHGCDVALRMGYKEYPDENAYGDAYYIKDGLKWIFNI
                     TGLKKRLGVYSDDDLRKQNYDVDTYYRVENQQEESADDEMQSLYHNLAVEEGEPVYLE
                     GGMYLYPDGSIR"
     gene            complement(5186..5280)
                     /locus_tag="OPV72_001920"
     tRNA            complement(5186..5280)
                     /locus_tag="OPV72_001920"
                     /product="tRNA-Sec"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5244..5246),aa:Sec,seq:tca)
     gene            5568..6950
                     /locus_tag="OPV72_001921"
     CDS             5568..6950
                     /locus_tag="OPV72_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside-pentoside-hexuronide family
                     transporter"
                     /protein_id="HCR9914231.1"
                     /translation="MKSEILSVKEKIGYGMGDAASHIIFDNVMLYMMFFYTDIFGIPA
                     GFVGTMFLLARALDAISDPCMGLLADRTRSRWGKFRPWVLFGALPFGIVCVLAYSTPD
                     LSLNGKMIYAAITYTLLTLLYTVVNIPYCALGGVITNDPTQRISLQSWRFVLATAGGM
                     LSTVLMMPLVKLIGGENKALGFQGGIAALSVVAFLMLAFCFFTTKERVEAPATHTSMR
                     EDLRDIWHNDQWRIVGLLTILNILAVCVRGGAMMYYVTWILGKPGVFVAFLTTYCVGN
                     LIGSALAKPLTDWKCKVSVFWWTNALLAVISVAMFFVPMHATIAMFVFIFVIGVLHQL
                     VTPIQWVMMSDTVDYGEWCNGKRLTGISFAGTLFVLKLGLALGGALIGWMLAGGGYDA
                     AAKTQNSATISIIIALFTIVPAICYLLSAAIAKRYYTLKSPFLKTILEQLAQGAHRNE
                     QEFTHKELQN"
     gene            6962..9280
                     /gene="yicI"
                     /locus_tag="OPV72_001922"
     CDS             6962..9280
                     /gene="yicI"
                     /locus_tag="OPV72_001922"
                     /EC_number="3.2.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-xylosidase"
                     /protein_id="HCR9914232.1"
                     /translation="MKISDGNWLIQPGLNLIHPVQVFDVEQHGNEMVVYAAPRDVRER
                     TWQLDTPLFTLRFFSPQEGVIGVRMEHFQGALDNGPHYPLNVLQDINVEMQNNAEFAE
                     LKSGSLSVCVTKGELWSLDFLRNGVRITGSQLKNNGYVQDTNSGRNYMFERLDLGVGE
                     TVYGLGERFTALVRNGQTVETWNRDGGTSTEQSYKNIPFYITNRGYGVLVNHPQCVSF
                     EIGSEKVSKVQFSVESEYLEYFVIDGPTPKDVLNRYTQFTGRPALPPAWSFGLWLTTS
                     FTTNYDEATVNRFIDGMAERNLPLHVFHFDCFWMKAFQWCDFEWDPVTFPDPKGMIHR
                     LKAKGLKVCVWINPYIGQKSPVFQELKEKGYLLKRPDGSLWQWDKWQPGLAIYDFTNP
                     QACEWYADKLKGLVKMGVDCFKTDFGERIPTDVQWFDGSDPQKMHNHYAYIYNELVWN
                     VLKETVGVEEAVLFARSASVGAQQFPVHWGGDCYANYESMAESLRGGLSIGLSGFGFW
                     SHDIGGFENTAPAHVYKRWCAFGLLSSHSRLHGSKSYRVPWAYDDESCDVVRFFTEQK
                     CRMMPYLYREAARANEAGTPMMRAMMLEFPDDPACDYLDRQYMLGDAVMVAPVFSEAG
                     DVEFYLPEGRWTHLWRNDEVQGSRWHKQQHDFLSLPVYVRDNTLLALGNNSQKPDYAW
                     HEGTAFQLFHLDDGCEAVCEVPATDGSTIFTLQAKRTGNTITVSGEGEARNWTLCLRN
                     ITQISGTKCGSYAGSELGVVVTPQGNEVVITL"
     gene            complement(9383..11092)
                     /locus_tag="OPV72_001923"
     CDS             complement(9383..11092)
                     /locus_tag="OPV72_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AsmA family protein"
                     /protein_id="HCR9914233.1"
                     /translation="MKLIGRLLLYVLIACLVVIFGFYFLLQTRWGADHVSNWVSENSG
                     YHLTFDVMDHRFSAPSHLLLENVTFGRDGQPATLVAKTVDIGLSIRQLTAPLHVDTIL
                     LQDGTLNISVQTAPFPFEADRLQLRNMALNSPGSEWRLSAQRVNGGVMPWRPEAGRVL
                     GNKAQIQLSAGSLTLNDVPATNVLIEGSIDHDQMMLNTVGADMARGALTGVARRNADG
                     SWVVENLRLNDIRLQSDKSLSEFFAPLTTVPSLQIGRLEVTDSSLQGPDWAVTDLDLS
                     LRNLTLRKEDWQSQEGKLSMNASEFIYGSLHLLDPILNAEFSPQGVALRQFTTRWEGG
                     MVRTSGAWLRESKALILDDTAIAGLEYTLPENWKQLWMKPLPDWLNSLTLKKFSASRN
                     LVIDIDPTFPWQITALDGYGANLELVQHHQWGVWSGNATLNAAAATFNRVDVRRPSLS
                     LTANASTVNISDLSAFTEKGILEATASVSQQPQRQTQISLNGRGVPMDVLQQWGWPAL
                     PIAGDGNIQFTASGNIQADAPLKPTVNGQLHAVNAQKQQIMQTMQAGVVSGGEVTSTE
                     PAL"
     gene            complement(11213..12604)
                     /gene="xanP"
                     /locus_tag="OPV72_001924"
     CDS             complement(11213..12604)
                     /gene="xanP"
                     /locus_tag="OPV72_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine/proton symporter XanP"
                     /protein_id="HCR9914234.1"
                     /translation="MSVNAIEPADAQPVAQTQNSELIYRLEDRPPLPQTLFAACQHLL
                     AMFVAVITPALLICQALGLPAQDTQHIISMSLFASGVASIIQIKAWGPVGSGLLSIQG
                     TSFNFVAPLIMGGTALKTGGADVPTMMAALFGTLMLASCTEMVLSRILHLARRIITPL
                     VSGVVVMIIGLSLIQVGLTSIGGGYAAMSDNTFGAPKNLLLAGVVLAIIILLNRQRNP
                     YLRVASLVIAMAAGYLLAWFMGMLPENNAPVSQDILMVPTPLYYGLGIDWNLLLPLML
                     VFMITSLETIGDITATSDVSEQPVSGPLYMKRLKGGVLANGLNSFVSAVFNTFPNSCF
                     GQNNGVIQLTGVASRYVGFVVALMLIVLGLFPAVSGFVQHIPEPVLGGATLVMFGTIA
                     ASGVRIVSREPLNRRAILIIALSLAVGLGVSQQPQILQFAPEWVKNLLSSGIAAGGIT
                     AIVLNLILPPEKP"
     gene            12831..14036
                     /gene="gltS"
                     /locus_tag="OPV72_001925"
     CDS             12831..14036
                     /gene="gltS"
                     /locus_tag="OPV72_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016507315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/glutamate symporter"
                     /protein_id="HCR9914235.1"
                     /translation="MFELDTLSTLVAATLVLLLGRKLVQSVSLLKKYTIPEPVAGGLL
                     VAVALLVLKKSVGWEVNFDMTLRDPLMLAFFATIGLNANLASLRKGGRVVGVFLVVVV
                     GLLLMQNAIGIGMASLLGLDPLMGLIAGSITLSGGHGTGAAWSKLFVERYGFASATEV
                     AMACATFGLVLGGLIGGPVARYLVKHSTTPDGMPDDQAVPTAFEKPDVGRMITSLVLI
                     ETIALIAICLTVGKIVAQLLAGTVLELPVFVCVLFVGVILSNGLALVGFYRVFERAVS
                     VLGNVSLSLFLAMALMSLKLWELASLALPMLAILVVQTIFMALYAIFVTWRMMGKNYD
                     AAVLAAGHCGFGLGATPTAIANMQAITDRFGPSHMAFLVVPMVGAFFIDIVNALVIKL
                     YLMLPIFAQ"
     gene            complement(14072..16153)
                     /gene="recG"
                     /locus_tag="OPV72_001926"
     CDS             complement(14072..16153)
                     /gene="recG"
                     /locus_tag="OPV72_001926"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HCR9914236.1"
                     /translation="MSGRLLDAVPLNSLTGVGAAQSSKLAKIGLHTVQDLLLHLPLRY
                     EDRTHLYPIGELLPGIYATVEGEVLNCNITFGGRRMMTCQISDGSGILTMRFFNFNAA
                     MKNSLATGRRVLAYGEAKRGKYGAEMIHPEYRLQGDLSTPELQETLTPVYPTTEGVKQ
                     ATLRKLTDQALELLDTCAIAELLPPELAQGMMSLPEALRTLHRPPPTLQLADLETGKH
                     PAQRRLILEELLAHNLSMLALRAGAQRYHTQPLSTNNILKDKLLASLPFKPTSAQARV
                     VAEIERDMALDVPMMRLVQGDVGSGKTLVAALAALRAIAHGKQVALMAPTELLAEQHA
                     NNFRNWFEPLGVEVGWLAGKQKGKARQAQQEAIASGQVQMIVGTHAIFQEQVQFNGLA
                     LVIIDEQHRFGVHQRLALWEKGQQQGFHPHQLIMTATPIPRTLAMTAYADLDTSVIDE
                     LPPGRTPVTTVAIPDTRRHEIIDRVRNACTTEGRQAYWVCTLIEESDLLEAQAAEATW
                     EELKLALPELNIGLVHGRMKPAEKQAVMQAFKQGELHLLVATTVIEVGVDVPNASLMI
                     IENPERLGLAQLHQLRGRVGRGAVASHCVLLYKSPLSKTAQKRLQVLRDSNDGFVIAQ
                     KDLEIRGPGELLGTRQTGNAEFKVADLLRDQAMIPEVQRIARHIHERYPQQAQALIER
                     WMPETERYSNA"
     gene            complement(16159..16848)
                     /gene="trmH"
                     /locus_tag="OPV72_001927"
     CDS             complement(16159..16848)
                     /gene="trmH"
                     /locus_tag="OPV72_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(18)-2'-O)-methyltransferase
                     TrmH"
                     /protein_id="HCR9914237.1"
                     /translation="MNPKRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVG
                     VHEVHAIWPGSRMRTMASAAAGSNSWVQVKTHRTIDDAVAHLKGRGMQILATHLSDKA
                     VDFREIDYTRPTCILMGQEKTGITQEALDLADRDIIIPMIGMVQSLNVSVASALILYE
                     AQRQRQNAGMYLRENSMLPEDEQQRLLFEGGYPVLAKVAKRKGLPYPRVNQQGEIDAD
                     ADWWATMQAAG"
     gene            complement(16853..18964)
                     /gene="spoT"
                     /locus_tag="OPV72_001928"
     CDS             complement(16853..18964)
                     /gene="spoT"
                     /locus_tag="OPV72_001928"
                     /EC_number="3.1.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional GTP
                     diphosphokinase/guanosine-3',5'-bis pyrophosphate
                     3'-pyrophosphohydrolase"
                     /protein_id="HCR9914238.1"
                     /translation="MYLFESLNQLIQTYLPEDQIKRLRQAYLVARDAHEGQTRSSGEP
                     YITHPVAVACILAEMKLDYETLMAALLHDVIEDTPATYQDMEQLFGKSVAELVEGVSK
                     LDKLKFRDKKEAQAENFRKMIMAMVQDIRVILIKLADRTHNMRTLGSLRPDKRRRIAR
                     ETLEIYSPLAHRLGIHHIKTELEELGFEALYPNRYRVIKEVVRAARGNRKEMIQKILS
                     EIEGRLQEAGIPCRVSGREKHLYSIYCKMVLKEQRFHSIMDIYAFRVIVHDSDTCYRV
                     LGQMHSLYKPRPGRVKDYIAIPKANGYQSLHTSMIGPHGVPVEVQIRTEDMDQMAEMG
                     VAAHWAYKEHGETSTTAQIRAQRWMQSLLELQQSAGSSFEFIESVKSDLFPDEIYVFT
                     PEGRIVELPAGATPVDFAYAVHTDIGHACVGARVDRQPYPLSQPLSSGQTVEIITAPG
                     ARPNAAWLNFVVSSKARAKIRQLLKNLKRDDSVSLGRRLLNHALGGSRKLAEIPQENI
                     QRELDRMKLATLDDLLAEIGLGNAMSVVVAKNLQQGEAVVPTVAQSNHGHLPIKGADG
                     VLITFAKCCRPIPGDPIIAHVSPGKGLVIHHESCRNIRGYQKEPEKFMAVEWDKETEQ
                     EFITEIKVEMFNHQGALANLTAAINTTTSNIQSLNTEEKDGRVYSTFIRLTARDRVHL
                     ANIMRKIRVMPDVIKVTRNRN"
     gene            complement(18983..19258)
                     /gene="rpoZ"
                     /locus_tag="OPV72_001929"
     CDS             complement(18983..19258)
                     /gene="rpoZ"
                     /locus_tag="OPV72_001929"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013511051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HCR9914239.1"
                     /translation="MARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPEEND
                     KTTVIALREIEEGLINNQILDVRERQEQQEQEAAELQAVTAIAEGRR"
     gene            complement(19313..19936)
                     /gene="gmk"
                     /locus_tag="OPV72_001930"
     CDS             complement(19313..19936)
                     /gene="gmk"
                     /locus_tag="OPV72_001930"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HCR9914240.1"
                     /translation="MAQGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSVSHTTRAP
                     RPGEVHGEHYFFVNHDEFKTMIGREAFLEHAEVFGNYYGTSRETIEQVLATGVDVFLD
                     IDWQGAQQIREKMPQARSIFILPPSKIELDRRLRGRGQDSEEVIAKRMAQAVAEMSHY
                     AEYDYLIVNDDFDTALSDLKTIIRAERLRMSRQKQRHDALISKLLAD"
     gene            20193..21877
                     /gene="ligB"
                     /locus_tag="OPV72_001931"
                     /pseudo
     CDS             20193..21877
                     /gene="ligB"
                     /locus_tag="OPV72_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462639.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigB"
     gene            complement(21874..22491)
                     /locus_tag="OPV72_001932"
     CDS             complement(21874..22491)
                     /locus_tag="OPV72_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="HCR9914241.1"
                     /translation="MLLHVLYLIGITAEAMTGALAAGRRRMDTFGVIIIATATAIGGG
                     SVRDILLGHYPLGWVKHPEYVIIVATAAVLTTIVAPVMPYLRKLFLVLDALGLVVFSI
                     IGAQIALDMGEGPIIAVVAAATTGVFGGVLRDMFCKRIPLVFQKELYAGISFASAVLY
                     IALQHYVMNPDVVVISTLLFGFTARLLALRLKLGLPVFYYRHEGH"
BASE COUNT         5225 a         5794 c         6091 g         5415 t
ORIGIN      
        1 tgctctcatc aacttcttat atacaaattt aagactattt tatagagacg catgtaaact
       61 ttaagggggt gtaatgctaa tgccatggga aaatcttgta acttaacgcc gggagtcata
      121 ccttgccaat aagttgatct gacttaattc tgaacgtgac agtgtgagca accgacagac
      181 ttatcggtcg aagcaacttc agcttctggc ttctcttttc aattgctcat ttgatgaaaa
      241 ctctttcccg gagcacatta gtgagaaaca ggatgtggtc aaacccaatg tccatagatg
      301 tcgtcagtca cttcagaaat atccgcctcc tggcagatat ctttaaccgc tcgtccagct
      361 tcgaccaact taattacggc gatgttctga tgctcagtga gacgggcttt acgcatagag
      421 attccttcgt cagcagatcg atgacgtgat ctctaaatgt gaatagcacg attatgtggg
      481 atacgtacaa aaaattaaac taactgccag taatatgagt acttggtata agaatgtata
      541 cggatatatt actactgaaa tataataatg ggaggggtta agaataaaca ggacgtatgg
      601 gagaacaagg gtataaagat gaaatgcttg cagtatctaa tagataacaa tgaaaaatca
      661 ggtaactgag aaactattca gtgtttaggt tgatgtgata ttgagtcatt cagccgctac
      721 agcacattat caggataatt tcgtctggat aaaacggagg aatgaatcgc cacaggttta
      781 acagacaccg ctgagtcatt taagatgact taaagagaga agcccatgag cggtaaacgt
      841 tatcccaaag cgtttaaaat taaagcggta aaacaggtta ttgagcgcgg ccattctgtt
      901 tccagcgtcg caacacgtct tgatattact acccatagtc tttacgcctg gataaagccg
      961 ccacattcac gacggcatca tgttgacctg aatctgacgg ggcatacagg cagttctggc
     1021 tggaatcggg ctgtgtttat ggctatcgca agatctgtct cgatctgcgg gatatcagga
     1081 acaatgcggt gtaagcaaag tctggtggtt gatgcaacgt gtggggataa aggctcgggc
     1141 gatcacagga atcgtatttg aatgttaact tattgatttt atgtttatat tttgtattgg
     1201 ataaatgagt aacccccata agcaccccca aatgattttg cttgtggggt ttggggacat
     1261 cctgagctac tttttaggct ctgttttcca ctgtaacaaa gcggcgatat ctttctcacc
     1321 ttcggcttct tttaaacgcc gttgttgctc ggcaaactgg ctatattccg cctgcgcttt
     1381 ttcatcggcc attttcttac tgactttacc tgccccttgc aaaacctcac ggtcgttaaa
     1441 ttgcaggaac tgatccagct tatcctgcca gtcgcgtaaa aagacctgtt gacgacgacg
     1501 ggcctgatct tcggcgaaat ccagccacat gttaactacg cggttaagct cgctgacttc
     1561 atcctgagtg agataatttt ttgccaccgt cacgtcacat ttgcgcacct cttcaccttt
     1621 atagctggtc agccccatat gcggctggca ggcgtcagca cgctgatgaa tgagttcagc
     1681 ggcggtatac ccggtacagg caaaatgtaa cttgttctgg atggtttgaa aaaactgcgt
     1741 ggtttctttg agggacggtt gataatcggc ggccagagca aagatctcgc gtacccgcaa
     1801 ataaacccga cgttcgctgg cgcggatatc gcggatacgc tccagcatct catcgaaata
     1861 gtcgggtaca gccgatgaac ccacgggcgg atttttcagg cgctcatcgt ccatcacaaa
     1921 acctttgatc aggtattcct ggagcgtctg ggttgcccac tggcggaact gcgtgccgcg
     1981 cggggagcga acgcggtagc cgacagcgag tatcaacggc aaactaaagt attgaatctg
     2041 ataatttttc ccatcactgg cagttgttcg gtaaaaccga acaactgaat tttcttcaag
     2101 ctcgccatct gcaaagatgt tctttatatg ctcactgatg gtggctttag ctttaccgta
     2161 tagttcgcag atcattccct gagagagcca cagtgtattg ctttcaaagc ggcattcaac
     2221 acgcactttc ccgtcaccgc tggcaaacat aatgaattca cctgccgggg attgggttaa
     2281 gtatttatct tccatgtcgc ctccacttac atctgactcg tgatgctgta atccgcttag
     2341 tatgccagaa attcctggtg aagctcatta cgcagatagc gtttattttg gcgggtagcg
     2401 cccccggata gtgtttcatc acgatatcat tcatcttctc caccagatcc agacgcttaa
     2461 acgtgatatg cccactgcct ttctgaaagt agtgcataga gaataaatca tcctcaaaaa
     2521 cctgctgatg cgggttatca cgaatgaagt ccatcagtcg gatagtcaca tcgtgtcggt
     2581 tatcgggaat ggttttacca tccagcagga acaacatgcg ctccagatcc gcaatctggt
     2641 cacgccgtca gccccaattc aggctgtagc cccatcggtc gtgctttacc aggccgttaa
     2701 cgatgatccg cttaccgaag cagcagggat tattggtttt atagtcccag cttagccctt
     2761 taaatacatt gataatccca cgttcgaaaa catcctgttt attgtggtgg agttgttcaa
     2821 aggtgctcag gatgttggct tcgctgatgg ccggaagatc tcctccttcg agatttttag
     2881 cccactggct gcgggcttca gcgtccatta aggtcaacat cccggacttc agcatcagat
     2941 cgcgccaaat gctgcggtca atattacggg tgatcaccgg catcgcttta tcaaccggtt
     3001 gcatcaacca gcagtcaaag gaatggcgct gtcgcatcgc ccaatgctcc gctacatcac
     3061 caccgatgct ggaggtaagc cgcgagatgt catcaagctt atgaatcagg atttctatca
     3121 ggctcagcgc agcgtcgcgc cctgtgacga tgcattcaat actggtcgag caaattagct
     3181 cattatggtc agttaagact tcagcttctg tttgcatatt tttggtccat ataaaagcaa
     3241 acgcgcctgc cgggagtggc aggcgcatta tgcggtgaaa taaaggtgaa taaatattga
     3301 gggtgtaaat caggaaggcg actcgcaata aatcatgctg tcgccctgaa tcaggaatag
     3361 tggtgttaaa ttaatgcagg ggcgtggctc tgtaatacct gttcagcttc ttgctggaaa
     3421 aactggcgtg taatgctgaa gaattcatgc agtttatgat ctggcgaagg gaccagatca
     3481 agctgaagta attggtgcag atcccagtct ttctcaatat gttcttcaaa aagctgttcc
     3541 agctcttccc aatgattacg acgctccgtt tgaaggaatc cgctgttcag gttcaggtga
     3601 tcaatggtgt actgtgcgta ctcagcttcc tgctcagtta aatctattga aggaaccaca
     3661 tgcccattag ataaataggc aaaataacga gaacagtcag ggaggtggca atgaataaac
     3721 tgtgccatat ccacagattt attctttccc tgtacatgac caccgaacgt gttgatgcca
     3781 agctggggca aaccattctc agagtctaac gcgctggctg cgagattttg ataatcgaag
     3841 gttcgccctg gctgctggct tttattttcg acgtgttcaa tgtgatagcc gaggccacgc
     3901 aaatcagcac ggatttcgct gtaacagcaa agatgatatt gctcattgag cagaagcgtc
     3961 actaaatctg ctttgtctcg tctaaagttt cgccagcgac gggtcgattg atccgaatct
     4021 tgtggtggat tttcatttgc agtgagtaag gcatctgtcc ccggcgagtt ttgatcacat
     4081 gcctcattgt gccttccctt tcagaaagtt acggcatcga caaacgtagc gcctgcgtta
     4141 ataaacgtaa ggctatagtg ccttcaagta gatgagtaag ctgcgacgtt actgctcgta
     4201 tgaacaccat ccacccttat gatgtgagcc cgtaccccca tgtggatgtt gaccctttgg
     4261 gcaggcaagc gcaccggatg atgccgtgac ggtaataaaa gcgataatca tcgctgtaaa
     4321 taatctcttc atatataact cacattaata aattggaaca tattactacc tactacagaa
     4381 tacgcatact tgatacggac ttaggggata atataacgtg tactttagtt taaattctat
     4441 ccttcatgtg gcataggtta tcaggatagg ttttcgttat gaattttatc tgggatattg
     4501 aagcaacata ttgtgggggg gatatgagtt ataaatatgt tggtaagcat ggctgtgatg
     4561 ttgcattgcg gatgggctat aaagaatacc ccgatgaaaa tgcttatggt gatgcctatt
     4621 atattaaaga tgggttaaaa tggatattta atataacagg cttaaaaaaa cggcttggcg
     4681 tatacagcga cgacgatctc cgtaaacaga actatgatgt agatacctat tatcgggttg
     4741 aaaaccaaca ggaagaaagt gcagatgatg aaatgcaatc gctatatcat aatttagcgg
     4801 tagaagaagg agaacccgtg tatctggagg gaggcatgta tctttatccg gatggctcta
     4861 tacgttgatc tcataatttt ggtctggtaa gcgttatctc ttttgagaaa ggatgagtct
     4921 gtaagtatga cccacaagct cgtttggtga ttagttaagt cccgcccgcg ttagtcctgg
     4981 cgtactttta tcccttcttt gcggacgata tcccacaata aatggacgtt cggttttagc
     5041 aatcggtaaa tggtgattaa taaaataata ttccactttc tctctccacc tttcctttcg
     5101 tattatatgc aagaactagt cttaataata agcaaatact ttgtcccgaa atagaggacg
     5161 aatggtgggc atgagagaag gattttggcg gaagatcaca ggagtcgaac ctgcccggga
     5221 ccgctggcgg ccccaactgg atttgaagtc cagccgcctc accggagacg acgatcttcc
     5281 gcgcctcgat tgctacatgg aggcgcgcgc attatagcta cttcctggcg tttccacatc
     5341 ccctcccgtg cttttttaac ttccctttcc ttctgccatg atcggtttca tataaacccc
     5401 cataaaatcc attagttaca tttcatcaca ctttttggcg ctaccctgat cacagaaaac
     5461 aagaatcgta atttgataac caaataacgg aatattcacg ctcgcaggga aggtttacaa
     5521 aaactgtaac cggtatcagt gagcgttgtg agcgttaagg atgcgtaatg aaaagtgaaa
     5581 ttctctccgt taaggagaag attggctatg gtatgggcga tgccgccagc cacatcatct
     5641 ttgataacgt catgttatat atgatgttct tctataccga tattttcggc attcccgctg
     5701 gttttgtcgg caccatgttt ttactggcgc gtgcgcttga tgccatctcc gacccttgca
     5761 tgggcctgtt ggccgaccgt acccgctctc gctggggcaa attccgaccc tgggtgctgt
     5821 ttggcgcgtt gccgtttggt atcgtttgtg tgctggctta tagcacgccg gatctcagtc
     5881 tgaacggcaa aatgatttat gccgccatca cctacacgtt gctcaccctt ctgtatactg
     5941 tggtcaacat cccttactgc gcgttgggtg gtgtaataac caatgaccca acgcagcgta
     6001 tctccctgca atcctggcgc tttgtgctgg caacggcggg cggaatgctc tctaccgtac
     6061 tgatgatgcc tctggtgaaa ctgattggcg gcgagaataa ggcgctgggc ttccaggggg
     6121 ggatcgcggc gctctcggtg gtggcgttcc tgatgctggc gttctgcttt tttaccacca
     6181 aagagcgcgt tgaagcgcct gccacccata cctccatgcg tgaagacctg cgtgatatct
     6241 ggcacaacga ccagtggcgc atagtcggcc tgctcaccat cctgaatatt ctggcggtat
     6301 gcgtgcgcgg cggggcgatg atgtattacg tcacctggat attgggcaaa ccgggcgtgt
     6361 ttgtcgcctt cctcaccacc tattgcgtcg gcaacctgat tggctcggcg ctggcaaaac
     6421 cgttgaccga ctggaaatgc aaagtgagcg ttttctggtg gaccaacgcc ttactcgcag
     6481 taatcagcgt ggcgatgttc ttcgtaccga tgcacgccac gatcgctatg ttcgtcttta
     6541 tcttcgtgat tggcgtattg caccagttag tcacgcctat ccagtgggtg atgatgtctg
     6601 acaccgtcga ctacggcgaa tggtgtaacg gcaaacgcct gacggggatc agttttgccg
     6661 gcacgttgtt cgtgctgaaa ctgggtcttg ccctcggcgg ggcgctgatt ggctggatgc
     6721 tggcaggcgg cggttacgac gcggcggcga aaacgcaaaa cagcgccacg atcagcatca
     6781 tcatcgctct gttcactatc gtcccggcca tctgttatct gctgagcgcc gcgatcgcta
     6841 aacgctacta caccctgaaa agcccgttcc tgaaaaccat tctggaacaa ctggcgcagg
     6901 gcgcacaccg caacgaacaa gaatttaccc ataaagaatt gcaaaactaa aggaacagac
     6961 tatgaaaatt agcgacggaa actggctgat ccagcctggc cttaatttga ttcacccggt
     7021 tcaggtgttc gacgttgaac agcacgggaa tgagatggtg gtctatgccg cgccgcgcga
     7081 tgtccgcgaa cgaacctggc aactggatac cccgttgttt accctgcgct ttttctcgcc
     7141 acaggaagga gtgataggtg tacggatgga acacttccag ggcgctttgg ataacggccc
     7201 acattatccg ctcaatgtct tgcaagatat caacgtggag atgcagaaca acgccgaatt
     7261 tgccgaactc aagagcggca gcctgagcgt gtgtgtcacc aaaggcgagc tctggtcact
     7321 ggattttctg cgcaacggtg tacgtatcac cggtagccag ttgaagaata acggctatgt
     7381 gcaggatacc aacagcgggc gcaactacat gttcgagcgt ctggatctcg gcgtgggcga
     7441 aaccgtctac gggctgggcg agcgctttac cgcgctggtg cgtaacggtc agacggtgga
     7501 gacctggaac cgtgacggcg gcaccagcac cgagcaatcg tacaagaata tcccgttcta
     7561 tatcaccaac cgtggctacg gtgtgctggt gaatcatccg cagtgcgtgt cgtttgaaat
     7621 tggctccgag aaagtctcca aagtccagtt cagcgtcgag agcgagtatc tggaatactt
     7681 cgtcatcgac ggcccgactc cgaaagacgt gctgaaccgc tatacccaat ttacgggtcg
     7741 tccggcgctg ccgcccgcct ggtcgtttgg cctgtggctg accacctcat ttaccaccaa
     7801 ctacgacgaa gcgaccgtta accgctttat cgacggtatg gccgagcgca atctgccgct
     7861 gcatgtcttc cacttcgact gtttctggat gaaggccttc cagtggtgcg attttgaatg
     7921 ggacccggtg actttccccg atccgaaagg gatgattcac cgcctgaaag cgaaagggct
     7981 gaaagtctgc gtgtggatta acccctacat cggccagaaa tccccggttt tccaggagct
     8041 gaaagagaaa gggtatttac ttaaacgccc ggacggctcc ttgtggcagt gggataaatg
     8101 gcagccggga ctggcgattt acgacttcac caacccgcaa gcctgcgaat ggtatgccga
     8161 caagctgaag ggcctggtga agatgggagt ggactgcttc aaaactgact tcggcgaacg
     8221 cattccaacg gatgtgcagt ggtttgatgg ttcagatcca cagaaaatgc acaaccatta
     8281 tgcctacatc tacaacgaac tggtgtggaa cgtgctgaaa gagaccgtgg gcgttgaaga
     8341 ggcggtgttg ttcgcccgtt ccgcctcggt gggcgcgcaa cagttcccgg tgcactgggg
     8401 cggcgactgc tacgccaatt acgaatcgat ggcggaaagc ctgcgcggcg ggctgtccat
     8461 cggcctgtca gggtttggct tctggagcca tgatattggc ggattcgaga ataccgcgcc
     8521 ggcgcatgtc tacaagcgtt ggtgcgcatt cggcttgctc tccagccaca gccgcctgca
     8581 cggtagcaaa tcctaccggg ttccgtgggc ctatgacgac gagtcctgtg acgtggtgcg
     8641 cttcttcacc gaacagaagt gccggatgat gccgtatctg tatcgggaag cggcgcgcgc
     8701 caacgaagcc ggtacgccaa tgatgcgggc gatgatgctg gagtttccgg acgatccggc
     8761 gtgtgattat cttgatcgcc agtacatgct gggagatgcg gtcatggtag cgccggtatt
     8821 tagtgaagcg ggcgacgtgg agttctacct gccagaaggc cgctggacgc acttgtggcg
     8881 caacgatgaa gtgcagggca gccgctggca taaacagcag catgacttcc tgagcctgcc
     8941 agtgtacgtg cgtgacaata cactactggc gctgggcaac aatagccaga agcccgatta
     9001 cgcctggcat gagggtacgg ccttccagtt attccatctg gatgacggtt gcgaagcggt
     9061 ctgcgaagtc cctgctacgg atggttcgac aatctttacg ctgcaggcga aacgcacagg
     9121 caataccatt acggtgagcg gcgaaggcga ggcgcgcaac tggacgctgt gtctgcgtaa
     9181 tattacgcag attagcggta ccaaatgcgg ctcatatgcg ggaagtgaac tgggcgtagt
     9241 ggtcaccccg cagggaaatg aagtggtgat tacgctttaa atctgaatcg ccggatggcg
     9301 ccgtgagctg cgcttatccg gcctacaaat gagcaagaac cgtaagcccg gtaagcgcca
     9361 gcgccaccgg gcaagccctc aattacagcg ctggctccgt tgacgtaact tccccgccgg
     9421 acaccacacc cgcttgcatc gtttgcatta tctgctgctt ttgtgcgttg accgcgtgta
     9481 attgcccgtt taccgtcggt ttcaacggcg catcggcctg aatattgccg ctggccgtga
     9541 actgaatatt gccatcgcca gcaatcggta atgccggcca gccccactgt tgtagcacat
     9601 ccattggtac gccgcgtccg ttcaggctga tttgcgtctg acgctgcggc tgttgtgata
     9661 cgctggcagt ggcttccagt atcccttttt cagtaaacgc gctcagatca ctgatgttga
     9721 ccgtgctggc attcgccgtc aacgacagcg acgggcggcg cacgtccaca cggttaaagg
     9781 ttgccgctgc ggcgttgagg gtcgcattgc cgctccagac gccccattga tgatgttgta
     9841 ccagctccag gtttgcgccg tagccgtcca gagcggtgat ttgccacggg aaggtcgggt
     9901 cgatatcgat caccagattg cggctggcgc tgaatttttt cagcgtcagg ctgttcagcc
     9961 agtcgggcaa cggcttcatc cataactgct tccagttttc cggcagcgta tactccagcc
    10021 cggcgatagc ggtatcgtcc agaatcagcg ctttgctctc gcgtaaccag gcgccggagg
    10081 ttctgaccat accgccttcc cagcgggtgg tgaactggcg tagcgcaacg ccctgtggtg
    10141 aaaattcggc gttcaggatt ggatcgagca agtgcagcga gccgtaaata aactcgctgg
    10201 cattcatcga taatttacct tcctgacttt gccagtcttc tttgcgcaga gtcagattgc
    10261 gcaaactcag gtcaagatcg gtgactgccc agtctggtcc ttgcaggctg gagtccgtca
    10321 cttcaagacg accaatctgc aaagatggaa ccgtagtaag cggcgcgaaa aactcgctca
    10381 gggatttatc gctttgtaac cggatatcat tcagccgcag attttcaacg acccaactac
    10441 catcagcgtt acgccgggcg acgccggtta acgctccgcg cgccatatcg gcgccgacgg
    10501 tgtttaacat catctgatca tggtcaatac tgccttcaat aagcacattc gtggcgggaa
    10561 cgtcgtttaa cgtcagcgaa ccggcgctca gttggatctg ggctttattg cccaataccc
    10621 gaccggcttc ggggcgccag ggcataacgc cgccgttaac gcgctgggcg ctcaaccgcc
    10681 attcgctgcc gggactattg agcgccatat tgcgaagttg caggcggtcg gcctcaaacg
    10741 ggaaaggggc ggtttgcact gaaatattca gcgtgccgtc ctgtaacaga atcgtgtcga
    10801 catgcagcgg cgcggttaac tggcgaatgc tcagaccgat atctacggtt ttcgcgacca
    10861 gggtagcagg ctgaccatca cgaccaaagg tcacattctc cagtaaaaga tgggatgggg
    10921 cggaaaaacg atgatccatc acgtcgaatg tgaggtgata gccgctgttc tctgataccc
    10981 agttgctgac atgatctgcg ccccagcgcg tttgcagcag aaaataaaag ccgaaaatca
    11041 ccactaaaca ggcgatcagc acgtagagaa gcaacctccc aatcaatttc atggtcttcc
    11101 atcccgtgaa atgcacatag gggatttatg cacgatttgc gtgcaatcct caagacagga
    11161 atggtgaaag agcgttacag cagcggcgaa tcgtgtcgcc gccgcagggt ttttacggtt
    11221 tttccggcgg gagaatcagg ttcagcacga tagccgtgat gccgccagcg gcaattccgg
    11281 atgagagcag atttttcacc cattccggcg cgaactgcag gatctgcggc tgttgcgaga
    11341 cgccaagacc cacggccagc gacagggcga taatcagaat cgcgcggcgg ttcagcggct
    11401 cacgcgagac aatacgcacc ccggaggcgg caatggtgcc gaacatcacc aacgtggcgc
    11461 cgccgagcac cggttccggg atatgttgca caaaaccgct taccgccggg aacaggccga
    11521 gcacaatcag catcagcgcg acgacaaatc ccacatagcg actggcgacg ccggtcaact
    11581 gaatgacgcc gttgttctga ccgaaacagg aattcgggaa cgtattaaat accgctgaaa
    11641 caaatgagtt caggccgtta gccagtacgc cgccctttag ccgtttcatg tacaaggggc
    11701 cggataccgg ctgctcggag acatcagagg tggcggtgat gtctccgatg gtctccagcg
    11761 acgtaatcat aaagaccagc atcaacggca gtaacaggtt ccagtcaatg cccagaccat
    11821 aatacagcgg ggtcggcacc atcaggatgt cctgcgagac cggcgcgtta ttctcaggca
    11881 acatgcccat aaaccaggcc aaaagatagc ctgccgccat ggcaataacc aaagaagcca
    11941 cgcgcaggta gggattacgt tgccgattca gcaggatgat aatggccagg acgacgccgg
    12001 ccagtaacag gtttttcggt gcgccaaagg tgttgtcgct catggcggca tagccgccgc
    12061 cgatggaagt tagccccacc tgaatcagcg acaggccaat aatcattacc acgacgccgg
    12121 agactaacgg cgtgataatc cggcgcgcca gatgtagaat gcgagaaagc accatctcgg
    12181 tgcagcttgc cagcatcagc gtgccgaaca gcgccgccat catcgtcggg acatccgcgc
    12241 cgccggtttt cagcgcggta ccgcccataa tcagcggggc gacaaagtta aaactggttc
    12301 cctggatgga taacagcccc gatcctaccg gcccccacgc tttgatttga ataatagagg
    12361 ctacgccgga ggcgaacagc gacatgctga taatgtgctg agtatcctgc gccggtaaac
    12421 ccaacgcctg gcagattaac agcgctggcg taattaccgc gacaaacatg gccagcagat
    12481 gctgacaagc ggcaaaaagg gtttgaggga gcggcgggcg atcttcaaga cggtaaatta
    12541 attcgctgtt ttgcgtctgc gcaaccggtt gcgcatctgc cggctcgatg gcgttaacgg
    12601 acatcaggga cattctcgtg gtggaaaagc ggtgatttta tctgaccagg tggtaaaagc
    12661 aaacgattgc gagcgaatat tcttaatatt taaaaaagat aaatgcacct tttatataac
    12721 tttttgcctt tttctgctta aaatccatgc cgaagactcg caaagagcta aaaaactgac
    12781 tcaggaaatg atttgtgcgc acatgtcaca gcgcactaca ggagctttaa atgtttgaac
    12841 tcgatacctt atcgaccctt gtcgccgcca cgctggtgct gctactgggt cgcaagctgg
    12901 tccagtctgt ctccttactg aagaaatata cgattccgga gccggtggcg ggggggctac
    12961 tggtcgcggt tgctctgctg gtgctgaaaa aaagcgtcgg ttgggaggtc aactttgata
    13021 tgaccctgcg cgatccgttg atgctggcgt ttttcgcgac gatcggcctt aacgctaacc
    13081 ttgccagcct gcgcaagggg ggacgcgttg ttggcgtctt cctggtcgtc gtggtcggat
    13141 tactgctgat gcagaatgcc atcggtatcg gcatggcgag tctgttgggg ctggacccgt
    13201 taatggggct gattgccggg tcaattacgc tgtccggcgg acacggtacc ggcgcggcgt
    13261 ggagtaaact gtttgtcgaa cgttatggtt ttgccagtgc caccgaagtt gcgatggcat
    13321 gtgcaacctt tggcctggtg ctgggcgggt tgattggcgg cccggtagcg cgttatctgg
    13381 tgaaacactc caccacgccg gatggaatgc ctgacgatca ggccgtgccg acagcctttg
    13441 aaaagccgga tgtgggtcgt atgatcacct ctctggtgct aatcgaaact atcgccctga
    13501 ttgctatctg tctgaccgtg ggcaaaatcg tagcgcagct actggcggga acggtgcttg
    13561 aactgccggt cttcgtttgt gtgctatttg ttggggtgat cctcagcaat ggcctggcgc
    13621 tggtgggttt ttatcgcgta tttgagcgtg ctgtttcggt gctggggaac gtgagtttgt
    13681 cactgttcct agcaatggcg ctgatgagcc tgaagctgtg ggaactggcg tcactggcgc
    13741 tgccgatgct ggcgattctg gtggtacaga ccatcttcat ggcgctgtac gcgatcttcg
    13801 tcacctggcg catgatgggg aaaaactatg atgcggcggt gctggcggcg ggtcactgtg
    13861 gttttggcct gggcgcaacg ccgaccgcca ttgctaatat gcaggcgatt accgaccgtt
    13921 ttggcccctc gcatatggcg ttcctggtgg tgccaatggt cggcgcgttc tttatcgata
    13981 tcgtcaatgc gctggtgatt aagctgtact tgatgttacc gattttcgcg caataagggt
    14041 ttgtacggcg gcattaaagc cgccgtgctc actaggcgtt agaataacgt tcggtttccg
    14101 gcatccagcg ctcaatcagc gcttgtgcct gctgcggata acgttcgtga atatgacggg
    14161 caatacgctg aacttcggga atcatggctt gatcgcgcag caaatcagct actttaaatt
    14221 cggcgttacc cgtctggcgc gtgcccagta attcccccgg gccgcgaatc tctaaatctt
    14281 tttgtgcaat cacaaagccg tcgttgctgt cgcgcaatac ctgtaaacgc ttctgcgccg
    14341 ttttcgacag cggcgattta tagagcagca cgcagtgcga tgcgaccgcg ccacggccaa
    14401 cgcgccctct gagctggtgt aattgcgcca ggcccagccg ctccgggttt tcaataatca
    14461 tcaggctggc gttaggaaca tcgaccccca cctcaatcac cgttgtggcg accagcagat
    14521 gcagttcacc ctgcttaaag gcctgcatca ccgcctgttt ttcggcgggc ttcatgcggc
    14581 cgtgtaccag gccgatattc aactccggta acgccagctt gagctcctcc caggtggctt
    14641 ccgccgcctg cgcttccagc aggtcggact cttcaatcag cgtacagacc cagtaggcct
    14701 gacggccttc ggttgtgcag gcgttgcgca cacgatcaat gatttcatgg cgacgggtat
    14761 ccggaatcgc aacggtagtg acaggggtac ggcccggcgg tagctcgtca atcaccgagg
    14821 tatcgagatc ggcgtaggca gtcatcgcca gggtgcgcgg tatgggcgtt gcggtcataa
    14881 tcaactgatg cggatgaaag ccctgctgct ggcctttttc ccacaatgcc agccgctggt
    14941 ggacgccaaa gcggtgctgc tcatcgataa tgaccagcgc caggccgttg aactgcacct
    15001 gttcctgaaa gatagcgtgg gtgccgacaa tcatctgcac ctgaccgctg gcaatagcct
    15061 cttgctgcgc ctgacgcgct ttaccttttt gcttacccgc cagccaaccc acttcaacgc
    15121 ccaacggttc gaaccagttg cggaaattat ttgcgtgctg ttcagccagc agttcggtcg
    15181 gtgccatcaa cgcgacctgc ttaccgtggg caatagcgcg caaggcggca agcgccgcaa
    15241 ccagcgtttt ccctgagccg acgtcgccct gaaccagacg catcatcggc acatccagcg
    15301 ccatatcacg ttcgatctct gctaccaccc gcgcctgcgc gctggtgggt ttaaacggca
    15361 acgacgccag cagcttgtct ttcaatatgt tgttggtact tagcggctga gtgtggtagc
    15421 gctgcgcgcc tgcgcgaagc gccagcatac tgaggttatg cgccagtagc tcttcaagaa
    15481 taagccgccg ctgcgccggg tgtttgccgg tttctaaatc ggcgagctgg agtgtcggcg
    15541 gcgggcgatg caaggtacgt agcgcttccg gcaggctcat cataccctgc gccagttccg
    15601 gcggcagtag ttcggcaatg gcgcaggtgt cgagcaactc cagcgcctga tcggtaagct
    15661 tgcgcagtgt cgcttgcttc acgccctcgg tggtcggata gacgggggtg agcgtttcct
    15721 gaagttccgg cgtgctgaga tcgccctgca ggcgatattc cggatggatc atctctgcgc
    15781 catacttgcc gcgcttcgct tccccgtagg ccagcacacg ccgccccgtc gccaggctgt
    15841 ttttcatcgc cgcgttaaaa ttgaaaaagc gcatggtaag aatgccggaa ccgtcgctaa
    15901 tctggcaggt catcatccgg cgaccgccga aagtgatatt gcagttcagc acttcacctt
    15961 caacggtggc gtagatgcca ggcagcagtt cgccaatggg gtagagatgg gtacggtctt
    16021 cgtaacgcag aggaagatgt aatagtaaat cctggacggt atgcaggcca attttcgcca
    16081 gtttactgct ttgcgctgcg ccgacgcctg tcagggaatt gagcggaaca gcgtctaaca
    16141 agcggcctga catggtgatt accctgccgc ctgcatcgtc gcccaccagt cagcatcggc
    16201 gtcgatttcg ccctgctgat tgacgcgagg ataaggcaga cctttacgtt tagcgacttt
    16261 cgccagcacc ggataaccac cctcaaacag caggcgctgc tgttcatctt ccggcaacat
    16321 gctattttca cgcagataca tgcccgcgtt ctgtcgctgg cgctgggctt cataaagaat
    16381 gagcgcggag gcgacggaaa cgttcagcga ctgtaccatg ccgatcatcg gaatgatgat
    16441 gtcccgatcc gccaggtcta atgcttcctg agtaataccg gttttctcct gacccatcag
    16501 aatacaggtc gggcgcgtgt aatcaatctc gcgaaagtct acggccttat cagaaagatg
    16561 ggtggccaga atctgcattc cccgtccttt caaatgggct accgcatcgt caatggtacg
    16621 gtgagttttc acctgtaccc aactgttgct gcccgccgcc gcggaagcca tggtgcgcat
    16681 ccggctacca ggccagatgg catggacttc atggacgcca acggcatctg cggtacgaat
    16741 gattgcagaa acgttatgag gtttgtggac ttgctccatg cagaccgtga gatcaggctg
    16801 acgcctggcg agcatttcgc atatacgcgc ataacgtttt ggattcatag cgctagtttc
    16861 ggttacgggt gactttaata acgtctggca tcacgcggat tttgcgcatg atattcgcca
    16921 gatgtacgcg atcgcgtgcg gtaaggcgaa taaaggtact atagacgcga ccatcttttt
    16981 cttcagtatt caggctttga atattggagg tggtggtatt aatcgccgcc gtcaggttag
    17041 ccagcgcgcc ctgatggtta aacatttcca ccttgatttc ggtaatgaat tcctgctccg
    17101 tctctttgtc ccattcgacc gccataaatt tctctggctc tttctggtat ccacggatat
    17161 tacggcagga ttcatggtgg atcaccagtc ctttacctgg gctgacgtga gcgatgatcg
    17221 ggtcgcctgg gatcggacga caacacttcg caaaggtgat aagcacgcca tccgcgcctt
    17281 taatcggcag gtggccgtga ttcgattgcg caacggtcgg caccacggct tcgccttgct
    17341 gcagattttt cgcgaccact acgctcatcg cgttgccgag accgatttcc gccagcagat
    17401 cgtcaagcgt tgccagcttc atacgatcca attcgcgctg aatattttcc tgcggaattt
    17461 ccgccagctt acgactgccg cctaaagcat ggttaagcag acgacggccc aggcttacgg
    17521 agtcatcacg tttgaggttt ttcagcaact gacgaatttt agcgcgcgct ttagagctga
    17581 cgacaaagtt cagccaggcg gcgttgggac gcgcgcccgg cgcggtaata atttcgacgg
    17641 tctgaccgct gctaagcggc tgtgacagcg gataaggctg ccggtcgaca cgcgcgccga
    17701 cgcaggcgtg gccgatgtcg gtatgcactg cataggcaaa atccaccggc gtagcgccag
    17761 cgggcagttc gacaatgcgc ccttccgggg tgaaaacgta aatctcatcc gggaagagat
    17821 cggattttac gctttcgata aattcaaacg aactaccggc gctctgttgt agctccagca
    17881 ggctctgcat ccagcgctgg gcgcggatct gcgccgtggt gctggtctca ccgtgctctt
    17941 tatacgccca gtgcgccgca acccccattt ccgccatctg atccatgtct tcggtacgga
    18001 tctggacttc aacaggaacg ccgtgcgggc cgatcatcga ggtgtgcaaa gactgatagc
    18061 cgttcgcttt gggaatggcg atatagtctt tcacgcgtcc cggacgcggc ttatagagac
    18121 tgtgcatctg gccgagtacg cgatagcagg tatcggagtc atgaacgatc acgcggaaag
    18181 cgtaaatgtc catgatcgag tgaaaacgct gctctttgag caccattttg cagtagatcg
    18241 agtaaagatg tttttcgcga ccgctaacgc gacacggaat tcccgcctct tgcaaacgtc
    18301 cttcgatttc agagaggatt ttttggatca tctctttacg gttgccgcgc gccgctctta
    18361 ccacttcttt aatgacgcgg taacgattgg gatacagcgc ttcaaaaccc agctcttcca
    18421 gctcggtttt aatatgatga atacctaaac ggtgcgccag cgggctgtag atttcgaggg
    18481 tttcacgggc aatacgacga cgtttatccg ggcgtaacga gcccagcgtg cgcatgttat
    18541 gggtacggtc agcaagctta atgaggatga cgcggatatc ctgcaccatc gccataatca
    18601 ttttgcgaaa gttttcggcc tgcgcctctt tcttatcgcg gaacttgagc ttatcaagtt
    18661 tcgacacccc ctctaccagc tcggcaacgc ttttaccgaa aagctgttcc atgtcctgat
    18721 aggtggcggg ggtatcttca atcacgtcat gcagcagagc ggccatcagc gtttcgtagt
    18781 cgagtttcat ctcggccaga atacaggcca ccgctaccgg gtgcgtgata tagggttcac
    18841 cgcttgaacg tgtctggccc tcgtgagcgt cacgtgcaac gagatacgcc tgccgaagac
    18901 gcttaatctg gtcttccggc aggtaggttt gaatcagttg attcaggctt tcaaacagat
    18961 acaagggcga cccgctttgt gattaacgac gaccttcagc aatagcggta acggcttgta
    19021 attcagcggc ttcctgctct tgctgttcct ggcgctcgcg gacgtcgagg atctggttgt
    19081 taatcagacc ttcttcgatt tcgcgcagcg cgataacggt agttttatcg ttttcttccg
    19141 gtaccagcgg atcctttccg cctacctgca tctgacgagc gcgacgcgcg gcgaccagta
    19201 ccaggtcaaa acggttacca attttctcta cagcgtcctg aacagttacg cgtgccatac
    19261 ttaaaatgct ccacaggtga agaaatgact gggcatgata ctgaaagtgg gttcagtctg
    19321 ccaacaattt gctgattaaa gcgtcatgac gctgcttttg gcggctcata cgcagacgtt
    19381 cagcgcgaat gatggttttc aagtcgctta acgcggtatc aaagtcgtca ttcacaataa
    19441 gataatcata ttcggcgtaa tggctcattt ctgcaaccgc ttgcgccatt cgtttggcaa
    19501 tgacttcttc gctatcttgc ccgcggccgc gtaaacggcg atccaattcg atctttgatg
    19561 gcggcaaaat aaaaatgctg cgtgcttgcg gcatcttttc gcgaatttgc tgggcgccct
    19621 gccagtcgat atccagaaaa acatcaacgc cagttgccag cacttgctca atggtttcgc
    19681 gcgaagtgcc gtagtaattg ccaaacactt ccgcgtgctc cagaaacgcc tccctgccaa
    19741 tcatggtttt aaactcatca tgatttacaa agaaatagtg ctcaccgtgc acttcacccg
    19801 gacgcggcgc gcgcgtggta tgtgaaacgg aaacctgagt gtcgtacaac ggttgggttt
    19861 ttaataaagc ctgaatcagg ctggatttac ccgcgccact gggggcagaa acaatataaa
    19921 gcgtaccttg agccatgagt atcttacgtc tgtgattatc gaaatagagc cttgatacgg
    19981 gcttattata cacatcgccg ttatgcgacg tagtctttgt cacacttttt gcgccagatt
    20041 attgcatttt gcgtcccttt ttccgctttt atcgcgtcgt tgcagcaacc caccaaaaaa
    20101 tctggaaagc ggctcggatg gtgcattttt acctgtcggt ttttattcac taaagcgcta
    20161 tacctgccgg gcaatgtgcg caggaggttg tgatgagatt atggaaaagt atggcgtggg
    20221 gaattttatt gtggcattcg cagagtgggg cgctttgccc ggcctggccg ccagcaaggg
    20281 ccgctgaaga aatcacccgt ttacagcaac agctcgctga ctggaatgac atctactgga
    20341 aacaaggtgt tagcgcggtt gacgatagtg tgtacgacca actcagcgca aggctggttc
    20401 agtggcaacg ctgtgttggt caggatgttt catctactcc ggtttcaccg ccgttaaacg
    20461 gtacaacaat gcaccctgtt gcgcacacgg gcgtacgtaa actcgcggac cgacaggcgt
    20521 agaacagtgg atgcgcgggc gcagcgagct ttgggtacag ccaaaagtgg atggcgtagc
    20581 ggtaacgctg gtttatcaaa acggtaaact gaccagggcc attagccggg gtaacggact
    20641 acaaggcgag gactggacgc caaaaattcg cctgatcccc tctataccgc agacaacaca
    20701 aggcgcgcta gctaacgcgg tgttgcaggg cgaaatcttt ctacagcgcg agggacatat
    20761 ccagcaacgg atgggcggga tgaatgcgcg ctcgaaagcc gcaggaatgt taatgcgcca
    20821 ggataacgcc tccgcgctaa attcgttggg tatttttatt tgggcgtggc cggacggtcc
    20881 ggcaaatatg cccgaaagat taagccaact tgctaaggct ggattcagtc tgacgaagaa
    20941 atattctctg gcggtaaaag atgccagcga ggtcgagcgg gcgcgccagt catggctgac
    21001 gtcagcatta ccctttgtga cggatggcgt agtgatacgc atggctaaag aacccgcgtc
    21061 acaatactgg cgacccgggc agggcgactg gctggcagca tggaaatatc cgccagtagc
    21121 gcaggtcgcg caagtgagcg ctattcagtt ctcggtgggg aaaagcggca agattaccgt
    21181 agtagcgtcg cttgtccccg ttatattgga tgataagcgg gttcagcggg tcaatatcgg
    21241 ttctgtgaag cgttgggaag cgtgggatat tgcgccgggc gatcagatcc tggtgagtct
    21301 ggccgggcaa ggcattcctc ggcttgatga ggtcgtctgg cggagtcgtg agcggagtaa
    21361 gcctgtgccg ccaggtagcc atttcaactc gctgacctgc ttttacgcgt cggcaacgtg
    21421 tcaggaacag tttatctcca ggctggtatg gctggggtca cggtcggcgt tgggtctgga
    21481 cggaatgggt gaagctagct ggcgggcttt gcatcagacg catcgctttg agcatatctt
    21541 ctcctggctt gccctgacgt cagcgcaaat agccaacacg ccaggcgttg ctaaaggaaa
    21601 aagcgagcag atatggcggc aatttaacct ggcgcgccgg cagtcattta cccgctggat
    21661 catggcgatg gatatcccct taacgcaggc cgcattacag gccagcggtg atcgctcatg
    21721 ggagcagtta ttaatgcgaa cagagcaaca ctggcggcaa ttgccagcga cgggcgagcg
    21781 ccgtgccggg agagttatcg actggcggaa taatccgcag atcaacgcgc tgagcagatg
    21841 gctggctact cagcatattc ccggatttgg gtcttagtgt ccttcatgac ggtaataaaa
    21901 taccggcagg ccaagtttaa gacgtagcgc taataacctt gctgtaaagc caaacagtag
    21961 cgtagagata acgacgacat ccggattcat gacgtaatgt tgtagcgcaa tatagagcac
    22021 cgccgaggcg aacgaaatgc cggcatacag ctctttttga aacaccagtg gaatgcgttt
    22081 gcagaacata tcgcggagca cgccgccaaa gacgccggta gtggcggcgg ctaccacggc
    22141 gataattggc ccttcgccca tatcaagggc tatctgagcg ccaataatag agaaaaccac
    22201 caaccccagc gcgtcaagta ccaggaaaag cttgcgtaaa tagggcatga cgggagcaac
    22261 aatggtggtc aatacggcgg cagtcgccac aataatgaca tattcgggat gcttcaccca
    22321 acccagcgga tagtgaccga gcagaatgtc gcgaaccgag cctccaccaa tggcggtggc
    22381 ggtagcaata ataattacgc cgaatgtatc catgcgacga cgacccgcag cgagtgcgcc
    22441 cgtcatggcc tcggcagtga tgccaattaa ataaagaacg tgcaacagca tgatttcccc
    22501 ctaatttact gggggcgaag attaa
//
LOCUS       DAJVBX010000059        22381 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.059, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000059 DAJVBX010000000
VERSION     DAJVBX010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 22381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22381
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.059"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            268..1848
                     /locus_tag="OPV72_001933"
     CDS             268..1848
                     /locus_tag="OPV72_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family protein"
                     /protein_id="HCR9914242.1"
                     /translation="MEWIADPSIWAGLVTLIVIELVLGIDNLVFIAILAEKLPPGQRD
                     RARITGLILAMIMRLLLLASISWLVTLTKPLFSVQALSFSARDLIMLFGGFFLLFKAT
                     MELNERLEGKDSANPTQRKGAKFWAVVAQIVVLDAIFSLDSVITAVGMVDHLAVMMAA
                     VIIAISLMLLASKSLTRFVNNHPTIVILCLSFLLMIGFSLVAEGFGFHIPKGYLYAAI
                     GFSVMIEALNQLAIFNRRRFLSANHTLRQRTTEAVMRLISGKKEDAELDAETAAMLAD
                     HDDSQIFNPQERRMIERVLNLNQRTVSSIMTSRHDIEHIDLNAPEAEIRALLEKNQHT
                     RLVVTGENEQEDLLGVVHVIDLLQQSLRGEPLNLRALIRQPLVFPETLPLLPALEQFR
                     NARTHFAFVVDEFGSVEGIVTLSDVMETIAGNLPNEVEEIDARHDIQKNPDSSWTANG
                     HMPLEDLVQYVPLPLDEKREYHTIAGLLMEYLQRIPQTGEEVQVGDYLLKTLQVESHR
                     VQKVQLIPLHNGEPDQEM"
     gene            complement(1934..3790)
                     /gene="asmA"
                     /locus_tag="OPV72_001934"
     CDS             complement(1934..3790)
                     /gene="asmA"
                     /locus_tag="OPV72_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane assembly protein AsmA"
                     /protein_id="HCR9914243.1"
                     /translation="MRRFLTTLMILLVVLVAGFSALVLLVNPNDFRAYMVQQVAARSE
                     YQLQLDGPLRWHVWPQLSILSGRMTLTARGASEPLVRADNMRLDVALWPLLSHQLHVK
                     QVMLKGGVIQLTPQTEAVRSDDAPVAPKDNTLPDVAEDRGWSFDIRSLRVAGSVLVFQ
                     HENDDQVTVRDIRLNMEQDAEHRGTFDFSGRVNRDQRDLALSFSGTVDASDYPHNLTA
                     GIEQLRWQLQGADLPAQGIEGQGQLQAQWQEAQKRLSFNHLNLTANDSSLTGHVQVTL
                     AEQPEWQIDLRSSKLNLDNLLPHHSAVAQTGGAVSQGQNTLPLTRPVIASRVGAPPYQ
                     GLQSFTAEIALQADSVRWRGMDFTQVSTKMSNQTGLLDITELQGKLADGEMSLPGTLD
                     ARTASPRIEFHPRLNHVEIGTILKAFNYPISLTGKMSLVGDFSGADIDAEAFRHSWKG
                     KAHVDMSNTRLEGMNFQQLVQQAVERSGGDAQQSQENMDNATRLDRFTTDLTLNKGTL
                     TLDDMVGQSSMLALTGSGTLDLVKQSCDTQFNLRVLGGWNGDSNLITFLKETPVPLRV
                     YGKWQELNYTLQVEQLLRKHLQDEAKRRLNDWADRNKDTRNGKDVKKLLNKL"
     gene            complement(3829..4410)
                     /gene="dcd"
                     /locus_tag="OPV72_001935"
     CDS             complement(3829..4410)
                     /gene="dcd"
                     /locus_tag="OPV72_001935"
                     /EC_number="3.5.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004942378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dCTP deaminase"
                     /protein_id="HCR9914244.1"
                     /translation="MRLCDRDIEAWLDEGRLSITPRPPVERINGATVDVRLGNKFRTF
                     RGHTAAFIDLSGPKDEVSAALDRVMSDEIVLPDGEAFYLHPGELALAVTFESVTLPPD
                     LVGWLDGRSSLARLGLMVHVTAHRIDPGWSGCIVLEFYNSGKLPLALRPGMLIGALSF
                     EPLSGPAARPYNRRQDAKYRDQQGAVASRIDKD"
     gene            complement(4501..5142)
                     /gene="udk"
                     /locus_tag="OPV72_001936"
     CDS             complement(4501..5142)
                     /gene="udk"
                     /locus_tag="OPV72_001936"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HCR9914245.1"
                     /translation="MTDQSHQCVIIGIAGASASGKSLIASTLYRELREQVGDEHIGVI
                     PEDSYYKDQSHLSMEERVKTNYDHPNAMDHSLLFQHLQALKRGSAIELPVYSYVEHTR
                     MQETVRVEPKKVIILEGILLLTDARLREEMNFSIFVDTPLDICLMRRIKRDVNERGRS
                     MDSVMAQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIAIDILKAKISQFFE"
     gene            5473..8463
                     /locus_tag="OPV72_001937"
     CDS             5473..8463
                     /locus_tag="OPV72_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MASE1 domain-containing protein"
                     /protein_id="HCR9914246.1"
                     /translation="MSKPSQHVFVTVPHPLLRLVSLGLVAFVFTLFSLVLSRVGTQLA
                     PLWFPTSIMMVAFYRHAGRLWPGIAVACSLGSIGASLTLFPAASLNFSWTAINIIEAA
                     TGAILLRKLLPSYNPLQNLNDWFRLAIGSAVIPPLLGGLLFWLIAPEAVASKAFLIWV
                     LSEAIGALTLVPLGLLFKPHYLLRHRDPHLLLETLLTLVITLALSWLAMRYIPWPFTC
                     VIVLLMWSAVRLPRMEAFLIFLATVIVVSLMLANDPTLLATPKTDVMVNMPWLPFLMI
                     LLPANMMTMVMYAFRTERKHITESESRFRNAMEYSAIGMALVGTEGQWLQVNKSLSHF
                     LGYSQDELRTMTFQQLTWPEDLNNDLEQLNMLVRGDINSYSMEKRYYTRNGDVVWALL
                     AVSLVRHKDNQPLYFIAQIEDINDLKQSEQENQRLMERITQANEALFQEKERLHITLD
                     SIGEAVVCIDVAMNITFMNPIAEKMSGWRQEDALGAPLLTVLRITSGNKGPLLEDIYR
                     ANRSRSDMEQEIVLHCHNGGSYDIHYSITPLSTLDGDKIGSVLVIQDVTESRKMLRQL
                     SYSATHDALTQLANRASFEKQLQQRLQTIQESPQHHALVFIDLDRFKAVNDSAGHAAG
                     DALLRELASLMLSMLRSGDLLARLGGDEFGLLLPDCNSDSARFIATRLINAVNEYHFM
                     WEGRLHRIGASAGITMINEHNCQLTEVVSQADIACYAAKNSGRGRLTVYEPQHALTSS
                     KGMMPLEEQWHMIKNNLLLMLARNVAPPRTPEATSFWLVSLRLWTSEGEVMEERAFRA
                     GLADSALHHALDRRVFHEFFRHAATAVASKGLSVALPLSAAGLYSATLIDELLEQLEH
                     SPLPPRLLHLIIPADVIVKQAQTAAATLRKLRQRGCQVILSHVGRDLQLFNLLPPHIV
                     DYLLLDSDLIANVHESLMDEMLTSIIQGHAQHLDIKTLAGPVQNPQVLDTLSRIGVDL
                     IYGDTIAEAQPLDLLLNTSYFAIH"
     gene            complement(8431..9300)
                     /gene="alkA"
                     /locus_tag="OPV72_001938"
     CDS             complement(8431..9300)
                     /gene="alkA"
                     /locus_tag="OPV72_001938"
                     /EC_number="3.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase 2"
                     /protein_id="HCR9914247.1"
                     /translation="MFTLSWQPPYDWSWMLGFLAARAVDGVETVGEGFYARSLVVGEH
                     RGLVSVRPHLPTHTVQVSVSAGLLPVAPACLAKVSRLFDLDCQPEQVAAVLGPLGEDR
                     PGLRLPGSVDTFEQGVRAILGQLVSVAMAARLTAKVARRYGEALPDAPDYVCFPGPET
                     LALADPLALKALGMPLRRAEALIHLAQATLAGKLALSAPPDIEQSVKNLQTFPGIGRW
                     TANYFALRGWQAKDIFLPDDYLIKQRFAGMTAAQIRRYAERWKPWRSYALLHIWYTHG
                     WQPSMDSEIAGIQ"
     gene            9434..10786
                     /gene="yegD"
                     /locus_tag="OPV72_001939"
     CDS             9434..10786
                     /gene="yegD"
                     /locus_tag="OPV72_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HCR9914248.1"
                     /translation="MFIGFDYGTANCSVAIMRDGHPQLLTMENNSALLPSMLCAPTRE
                     AVSEWLYRHHDVPATDEETQALLRRAIRYNREEDIEVGAQSVQFGLASLAHYIDDPQE
                     VWFVKSPKSFLGASGLKPQQVALFEDLVCAMMVHILHTAHSQLPEAITQAVIGRPINF
                     QGLGGDDANRQAQGILERAAKRAGFQEVVFQYEPVAAGLDYEATLREEKRVLVVDIGG
                     GTTDCSMLLMGPQWRQRADRENSLLGHSGCRVGGNDLDIALAFKNLMPLLGMGGETEK
                     GIALPVLPWWNAVAINDVPAQSDFYSSANGRLLNDLVRNAREADKVALLLKVWRQRLS
                     YRLVRCAEESKIALSGQADVTARLPFISDDLAVAISQQGLEAALDQPLARILEQVQLA
                     LDSAQEKPDVIYLTGGSARSPLIKKALSEQLPGIPVAGGDDFGSVTAGLARWAEVVFR
                     "
     gene            complement(10885..10998)
                     /locus_tag="OPV72_001940"
     CDS             complement(10885..10998)
                     /locus_tag="OPV72_001940"
                     /inference="COORDINATES: protein motif:HMM:NF025322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Ibs family toxin"
                     /protein_id="HCR9914249.1"
                     /translation="MLKRESPSRGRGQNKERVMMKVVIIMVILLVISLPAY"
     gene            11227..12468
                     /gene="mdtA"
                     /locus_tag="OPV72_001941"
     CDS             11227..12468
                     /gene="mdtA"
                     /locus_tag="OPV72_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter subunit MdtA"
                     /protein_id="HCR9914250.1"
                     /translation="MKGSNTFRWAIAIGVVVAAAAFWFWHSRSESPTAAPGVAAQAQH
                     TAAAGRRGMRDGPLAPVQAATATTQAVPRYLSGLGTVTAANTVTVRSRVDGQLIALHF
                     QEGQQVNAGDLLAQIDPSQFKVALAQAQGQLAKDNATLANARRDLARYQQLAKTNLVS
                     RQELDAQQALVNETQGTIKADEANVASAQLQLDWSRITAPVSGRVGLKQVDVGNQISS
                     SDTAGIVVITQTHPIDLIFTLPESDIATVVQAQKAGKTLVVEAWDRTNSHKLSEGVLL
                     SLDNQIDPTTGTIKIKARFTNQDDTLFPNQFVNARMLVDTEQNAVVVPAAAVQMGNEG
                     HFVWVLNDENNVSKKRVKIGIQDNRNVVISAGLSAGDRVVTDGIDRLTEGAKVEVVEP
                     QTTMADEKSPSRHEGQKGARA"
     gene            12468..15590
                     /gene="mdtB"
                     /locus_tag="OPV72_001942"
     CDS             12468..15590
                     /gene="mdtB"
                     /locus_tag="OPV72_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit MdtB"
                     /protein_id="HCR9914251.1"
                     /translation="MQVLPPGSTGGPSRLFILRPVATTLLMAAILLAGIIGYRFLPVA
                     ALPEVDYPTIQVVTLYPGASPDVMTSSVTAPLERQFGQMSGLKQMSSQSSGGASVVTL
                     QFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPIYSKVNPADPPIMTLAVTSNAMPM
                     TQVEDMVETRVAQKISQVSGVGLVTLAGGQRPAVRVKLNAQAIAALGLTSETVRTAIT
                     GANVNSAKGSLDGPERAVTLSANDQMQSADEYRKLIIAYQNGAPVRLGDVATVEQGAE
                     NSWLGAWANQAPAIVMNVQRQPGANIIATADSIRQMLPQLTESLPKSVKVTVLSDRTT
                     NIRASVRDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFS
                     INNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFS
                     LIAVLIPLLFMGDIVGRLFREFAVTLAVAILISAVVSLTLTPMMCARMLSRQSLRKQN
                     RFSRACERMFDRVIASYGRGLAKVLNHPWLTLSVAFATLLLSVMLWITIPKGFFPVQD
                     NGIIQGTLQAPQSSSYASMAQRQRQVAERILQDPAVQSLTTFVGVDGANPTLNSARLQ
                     INLKPLDARDDRVQQVISRLQTAVATIPGVALYLQPTQDLTIDTQVSRTQYQFTLQAT
                     TLDALSHWVPKLQNALQSLPQLSEVSSDWQDRGLAAWVNVDRDSASRLGISMADVDNA
                     LYNAFGQRLISTIYTQANQYRVVLEHNTASTPGLAALETIRLTSRDGGTVPLSAIARI
                     EQRFAPLSINHLDQFPVTTFSFNVPEGYSLGDAVQAILDTEKTLALPADITTQFQGST
                     LAFQAALGSTVWLIVAAVVAMYIVLGVLYESFIHPITILSTLPTAGVGALLALIIAGS
                     ELDIIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPRDAIFQACLLRFRPILMTT
                     LAALLGALPLMLSTGVGAELRRPLGIAMVGGLLVSQVLTLFTTPVIYLLFDRLSLYVK
                     SRFPRHKEEA"
     gene            15591..18671
                     /gene="mdtC"
                     /locus_tag="OPV72_001943"
     CDS             15591..18671
                     /gene="mdtC"
                     /locus_tag="OPV72_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit MdtC"
                     /protein_id="HCR9914252.1"
                     /translation="MRFFALFIYRPVATILIAAAITLCGILGFRLLPVAPLPQVDFPV
                     IMVSASLPGASPETMASSVATPLERSLGRIAGVNEMTSSSSLGSTRIILEFNFDRDIN
                     GAARDVQAAINAAQSLLPGGMPSRPTYRKANPSDAPIMILTLTSESWSQGKLYDFAST
                     QLAQTIAQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDEVREAIDSANVRRPQG
                     AIEDSVHRWQIQTNDELKTAAEYQPLIIHYNNGAAVRLGDVASVTDSVQDVRNAGMTN
                     AKPAILLMIRKLPEANIIQTVDGIRAKLPELRAMIPAAIDLQIAQDRSPTIRASLQEV
                     EETLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMAL
                     TIATGFVVDDAIVVLENIARHLEARMKPLQAALQGTREVGFTVISMSLSLVAVFLPLL
                     LMGGLPGRLLREFAVTLSVAIGISLVVSLTLTPMMCGWMLKSSKPRTQPRKRGVGRLL
                     VALQQGYGTSLKWVLNHTRLVGVVFLGTVALNIWLYIAIPKTFFPEQDTGVLMGGIQA
                     DQSISFQAMRGKLQDFMKIIRDDPAVNNVTGFTGGSRVNSGMMFITLKPRGERKETAQ
                     QVIDRLRVKLAKEPGAKLFLMAVQDIRVGGRQANASYQYTLLSDSLPALREWEPKIRK
                     ALSALPQLADVNSDQQDNGAEMNLIYDRDTMSRLGIDVQAANSLLNNAFGQRQISTIY
                     QPMNQYKVVMEVDPRYSQDISALEKMFVINRDGKAIPLSYFAQWRPANAPLSVNHQGL
                     SAASTIAFNLPTGTSLSQATEAIDRTMTQLGVPSTVRGSFSGTAQVFQQTMNSQLILI
                     VAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLI
                     GIVKKNAIMMVDFALEAQRSGGLTPEQAIFQACLLRFRPIMMTTLAALFGALPLVLSG
                     GDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLRFSRKNSKPVVEI"
     gene            18668..20080
                     /locus_tag="OPV72_001944"
     CDS             18668..20080
                     /locus_tag="OPV72_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR9914253.1"
                     /translation="MTEFPDNTRWQLWIVAFGFFMQSLDTTIVNTALPSMAKSLGESP
                     LHMHMVVVSYVLTVAVMLPASGWLADKIGVRNIFFAAIVLFTLGSLFCALSGTLNQLV
                     LARVLQGVGGAMMVPVGRLTVMKIVPRAQYMAAMTFVALPGQIGPLLGPALGGVLVEY
                     ASWHWIFLINIPVGIVGAMATFMLMPNYTIETRRFDLPGFLLLAIGMAVLTLALDGSK
                     SMGISPWTLAGLAAGGAAAILLYLFHAKKNSGALFSLRLFRTPTFSLGLLGSFAGRIG
                     SGMLPFMTPVFLQIGLGFSPFHAGLMMIPMVLGSMGMKRIVVQIVNRFGYRRVLVATT
                     LGLALVSLLFMSVALLGWYYLLPLVLLLQGMVNSARFSSMNTLTLKDLPDTLASSGNS
                     LLSMIMQLSMSIGVTIAGMLLGMFGQQHIGIDSSATHHVFMYTWLCMAVIIALPAIIF
                     ARVPNDTQQNMVISRRKRSL"
     gene            20080..21483
                     /gene="baeS"
                     /locus_tag="OPV72_001945"
     CDS             20080..21483
                     /gene="baeS"
                     /locus_tag="OPV72_001945"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     BaeS"
                     /protein_id="HCR9914254.1"
                     /translation="MKVWRPGITGKLFLAIFATCIVLLISMHWAVRVSFERGFIDYIK
                     HGNEQRLQMLGDALGDQYQQHGNWRFLRNNDRFVFQILRSFEHDNDRDKPGPGMPPHG
                     WRTQFWVVDQNGRVLVGPRGPVPHDGTRRPILVNGVEVGAIIASPVERLTRNTDINFD
                     MQQRRASWMIVALSTLLAALATFLLARGLLAPVKRLVEGTHRLAAGDFTTRVTPTSAD
                     ELGKLAQDFNQLASTLEKNQQMRRDFMADISHELRTPLAVLRGELEAIQDGVRQFTPE
                     SVTSLQAEVGTLTKLVDDLHQLSLSDEGALAYQKTTVDLVPQLEVAGGAFRERFTSRG
                     LTLHYALPDSMTVFGDPDRLMQLFNNLLENSLRYTDSGGGLHISAEQRDKSLFLTFAD
                     SAPGVSDEQLQKLFDRFYRTEVSRNRASGGSGLGLAICVNIVHAHNGHLHAAHSPFGG
                     VSITVELPLDRDLQREV"
     gene            21480..22202
                     /gene="baeR"
                     /locus_tag="OPV72_001946"
     CDS             21480..22202
                     /gene="baeR"
                     /locus_tag="OPV72_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator BaeR"
                     /protein_id="HCR9914255.1"
                     /translation="MTELPIDENTPRILIVEDEPKLGQLLIDYLRAASYAPTLINHGD
                     KVLPYVRQTPPDLILLDLMLPGIDGLTLCREIRRFSDIPIVMVTAKIEEIDRLLGLEI
                     GADDYICKPYSPREVVARVKTILRRCKPQRELQQQDAESPLMIDESRFQASWCGKALD
                     LTPAEFRLLKTLSLEPGKVFSREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLESLDAE
                     QSFIRAVYGVGYRWEADACRLV"
BASE COUNT         4828 a         6297 c         6142 g         5114 t
ORIGIN      
        1 tttttaagat taatattaaa tgaattaaca gatgatttta ggattttatt gatgttgaca
       61 atatttattt actccactcc acctgcgata tttcctaaat atattcttga cattatttag
      121 tttccgacag aaacattacg gctattttaa agttatttta tagccccgta acaaagataa
      181 attgctctgc ggcattgcat ttttccgccg tattatccat gatcgaattg tgacaattgt
      241 catattacag aaggtattgc tcttactatg gaatggattg ccgatccgtc aatctgggcc
      301 ggactggtaa cgttaatcgt tatcgaactt gttctcggca ttgataacct ggtctttatt
      361 gccatcctcg ctgaaaaact accgccgggg cagcgcgacc gcgcgcgcat taccggcctg
      421 atactggcga tgatcatgcg cctgctgctg ctggcgtcaa tctcgtggct ggtcaccttg
      481 actaagccgc tctttagcgt acaggcgtta agctttagcg cccgcgatct gattatgctg
      541 ttcggcggct tcttcctgct ctttaaagcc accatggagc tcaacgaacg gctggaaggg
      601 aaagatagcg ccaaccctac ccagcgtaag ggggcgaaat tctgggcggt ggtcgcgcaa
      661 atagtggtgc tggacgctat cttttctctc gactccgtga ttaccgccgt ggggatggtc
      721 gatcacctag cggtcatgat ggcggccgtg ataatcgcca ttagcctgat gctgctcgcc
      781 agcaagtccc tgacccgatt tgtgaacaac catcccacca ttgtcatttt gtgccttagc
      841 ttcctgctaa tgatcggctt tagcctggtg gcggaagggt ttggtttcca cattccgaaa
      901 gggtatctgt acgcggctat cggcttctcg gtgatgatcg aggcgctcaa ccaactggct
      961 atttttaacc gccgccgttt tctttccgct aaccatacgc tgcgccagcg cacaacggag
     1021 gccgtgatgc ggctgattag cggtaaaaaa gaggatgccg aactggatgc ggaaaccgcc
     1081 gcgatgctgg cagaccatga cgacagccag atttttaatc cgcaggagcg caggatgatt
     1141 gagcgggtgc tgaatctcaa ccagcgcacc gtaagtagca tcatgacgtc gcgtcacgat
     1201 atcgagcata tcgatctcaa cgcgccggaa gcggaaatcc gcgctctgct ggaaaagaac
     1261 cagcatacgc gtctggtcgt gacgggtgaa aatgaacagg aagatttact cggcgtcgtc
     1321 cacgtcatcg atctgttgca acaatcgctg cgcggcgaac cgctcaacct gcgggcgctg
     1381 attcgccaac cgctggtttt cccggaaaca ttgccgctgc tgcctgcgct ggagcagttc
     1441 cgtaacgcca gaacccattt tgcctttgtc gtagatgagt ttggctcggt tgaaggcatt
     1501 gtgacattaa gcgatgtcat ggagactatc gccggtaatc tgccgaatga agtcgaggaa
     1561 attgacgccc gccacgatat tcagaagaac ccggacagtt cctggacagc aaacggccat
     1621 atgccgctgg aggatttggt gcagtacgtg ccgctaccgc tggatgaaaa acgggaatac
     1681 catacgattg ccggattatt gatggaatat ttgcaacgca taccgcaaac cggtgaagag
     1741 gttcaggtgg gcgattattt gctgaaaaca ttgcaggtag aaagccatcg agtgcagaaa
     1801 gtgcagttaa ttccgctgca taacggcgag ccagaccagg agatgtaacg tctgttcgcc
     1861 tgccccggcc tgcttaccag gcaggccgga ggcgcgttag cctcgccatc cggctctgcc
     1921 ctttggccaa aaactacagc ttattcagca gcttcttcac atctttaccg ttgcgggtat
     1981 ctttattgcg atccgcccag tcattgagcc gacgcttcgc ctcatcctgt aaatgcttac
     2041 gcaataactg ctccacttgc agggtatagt tcagctcctg ccacttgcca tagacgcgca
     2101 acggcaccgg cgtctctttc aggaaggtga tcaggttgct atcgccgttc cagccgccca
     2161 gcacacgcag attaaattgt gtatcacagc tctgcttaac cagatccagc gttccgctgc
     2221 cggttaacgc cagcatagaa gattgcccga ccatgtcgtc gagcgtcagc gtgcccttat
     2281 ttagcgtcag atcggtcgtg aagcgatcca gtcgggtcgc gttgtccata ttttcctgcg
     2341 actgctgcgc gtcgccgccg cttcgctcta cggcctgctg caccagttgc tggaaattca
     2401 ttccttcaag gcgcgtattg ctcatgtcaa catgcgcttt tcctttccaa ctatggcgaa
     2461 atgcctctgc gtcaatatcc gccccggaga aatcgccaac cagcgacatc ttaccggtca
     2521 ggctaatcgg ataattgaag gctttcagga tagtcccaat ctcaacatgg ttgaggcgag
     2581 ggtggaattc gatgcgcgga ctggcggtgc gggcgtccag cgtgccgggc agcgacatct
     2641 ctccgtcggc cagtttcccc tgcaactcag taatatccag caatccggtc tgattagaca
     2701 tcttcgtcga aacctgggta aagtccattc cccgccagcg aactgaatcc gcctgtaaag
     2761 caatctccgc cgtaaagctt tgcagcccct gataaggcgg cgcaccaaca cgcgacgcga
     2821 taactggcct ggtcaggggg agcgtatttt gcccctgcga caccgcgccg cctgtctgag
     2881 ccacggcgct atgatgcggc aacaggttgt ccagattaag cttgctggac cggaggtcaa
     2941 tttgccattc cggctgctcc gccagcgtta cctgaacatg cccggtcaga gaactgtcat
     3001 tcgccgttaa atttaagtgg ttaaatgaaa gacgtttttg cgcctcctgc cactgcgcct
     3061 gcaattgtcc ctgcccctca atcccctgcg ccggtagatc cgcgccctgc aattgccagc
     3121 gcagttgctc aatacccgcg gttaaattat gcggataatc ggaagcatcc accgttccgc
     3181 tgaacgataa agcaagatcc cgctgatcgc ggttcacgcg tcccgaaaaa tcaaacgtgc
     3241 cgcgatgctc ggcatcttgt tccatattca gacgaatatc gcgcaccgtg acctgatcat
     3301 cattttcatg ctggaaaacc agcacgctgc cggcaacgcg caggctacga atatcaaacg
     3361 accagccgcg atcttccgct acgtccggca aggtattatc tttcggcgcg accggcgcat
     3421 catcactgcg taccgcttcc gtttgcggcg tcagttgaat caccccgcct ttcagcatca
     3481 cctgcttaac atgaagctga tgactcaaca gcggccataa agcgacatcc aggcgcatat
     3541 tgtcagcccg caccagcggt tcgctggcgc ctcgcgccgt tagcgtcatt cgcccggaaa
     3601 ggatactgag ttgcggccat acgtgccagc gcagcggccc gtccagttgc aactgatatt
     3661 cactacgcgc ggcaacctgc tgcaccatat aggcgcggaa atcattcgga ttgaccaaca
     3721 ataccaacgc agagaatccg gccaccagca cgaccaagag aatcatcagc gtcgtcagaa
     3781 atcgtctcat gctaccctca atggaccggc agtattgcgc cgaatggctc agtctttatc
     3841 aatccggctg gcaacagcgc cctgctgatc gcgatatttg gcatcctgac ggcggttata
     3901 aggccgcgcc gccgggccgg acagcggctc aaagctcagc gcgccgatga gcatacccgg
     3961 acgcaacgcc agcggcagct tcccggagtt gtaaaactca agcacaatgc agcccgacca
     4021 gccgggatcg atacggtgcg ccgtcacatg caccatcagt cccagacgcg ccagcgagga
     4081 acgaccatcc agccagccca ctaaatccgg tggcagggta acggattcaa aggtgacggc
     4141 cagcgccaat tcgcctggat gcagataaaa tgcctcgccg tccggcaaaa cgatttcatc
     4201 gctcatcacg cgatccaacg ccgcgctgac ctcatctttc ggcccgctca gatcgataaa
     4261 cgccgccgta tggccacgga aggttcgaaa tttattgcca agacgtacat cgaccgtcgc
     4321 gccgttaatg cgctctacgg gaggtcgcgg ggtgatagac aaacggcctt catccagcca
     4381 ggcttcaata tctcggtcgc ataaacgcat ggcactttct cctttcgcgc atcaagccct
     4441 taaatcaagc acatcaaggg ctaaccaggt tatcactgaa cggtacacaa ttcgccagat
     4501 ttattcaaag aactggctga ttttcgcttt cagaatatca atagcgatgc ggtttttacc
     4561 gccgcgcggc acgataatat ccgcatattg tttggaaggc tcaataaatt gcaggaacat
     4621 cggacgcacc gttttctgat attgcgccat caccgaatcc attgagcgac cacgctcgtt
     4681 cacatcgcgt ttgatacggc gcatcaaaca gatatccagc ggcgtatcga caaaaataga
     4741 gaagttcatc tcttcacgca aacgcgcgtc ggtcagtaac agaatacctt caagaataat
     4801 cactttcttc ggttctacgc gaaccgtttc ctgcatacgg gtatgctcaa cataactgta
     4861 taccggtaat tcaatcgccg aaccgcgctt gagcgcctga agatgctgaa atagcaggct
     4921 gtgatccatc gcattcggat ggtcatagtt agtttttacg cgttcttcca tcgacagatg
     4981 gctttgatct ttgtaataac tgtcttcggg aataacgcca atatgttcgt cacccacttg
     5041 ttcacgcaat tcgcggtaaa gggtactggc aataagactc ttgccggaag ccgatgcgcc
     5101 agcgataccg ataatgacgc actgatgaga ctgatcagtc ataaatttag cgacctgatt
     5161 aacctggatg taaagaaggg gggcgccgaa acgccaaacg cggcaattat agggatttca
     5221 gcagcacgat accagtccgg cgctatgcca cggtgaattt gttggcggcg cattcgacgt
     5281 cgcgacgtaa aagcgttcag ttttaatgcg gacagcggat ttatcgaccc gtctggagga
     5341 ggaatacgcc gggagccaca atttatattc agtcagcgta taaatcatta cgcgtttata
     5401 ctagcataat cacagagtaa actgacgcgt ccggtattcc gcgacgttac cggcgattcg
     5461 gatagagtgg taatgagtaa accatcccaa catgttttcg ttaccgtccc ccacccgcta
     5521 ttgcgtctgg tcagtttagg cctggtcgcg tttgtcttta cgctcttttc gctcgtatta
     5581 tcgcgtgtcg gcacccaact cgcgccgctg tggttcccca cctccattat gatggtcgcg
     5641 ttttaccgcc atgcgggccg tctgtggcct gggatcgcgg tcgcctgctc gctcggcagc
     5701 atcggcgcct cactgacttt atttcctgcc gcctcgctta actttagctg gacggcaata
     5761 aatattatcg aggcggccac tggcgcgata ctgctacgaa aactgctccc cagctacaac
     5821 cccttacaaa atttgaatga ctggtttcgt ctggctatcg gcagcgccgt gattccgccg
     5881 ctactcggcg gcctgttatt ttggctgata gcgccggaag cggtcgcctc gaaagcgttt
     5941 ctgatttggg tattatcgga agccatcggc gcgctgacgc tggtgccgtt aggtttactg
     6001 tttaaaccac actatctgtt gcgtcatcgc gacccgcatc tgttgctgga aacgctattg
     6061 acgctggtca ttacgctggc gctaagctgg ctcgctatgc gctatattcc gtggccgttt
     6121 acgtgcgtta tcgtcctgtt gatgtggagt gcggtgcgcc tgccgcgaat ggaggcgttt
     6181 ttaatttttt tagctaccgt tatcgtggtc tcgctcatgc tggccaatga ccccacgctg
     6241 ctcgccacgc cgaaaaccga cgtgatggtc aatatgccgt ggctgccttt tttaatgatc
     6301 ctgctgcctg ccaatatgat gacgatggtg atgtacgcgt ttcgcacgga gcgcaaacat
     6361 atcaccgaga gcgaatcccg ctttcgcaac gcgatggagt attccgccat tggtatggcg
     6421 ctggtcggta cggagggtca gtggctacag gtcaataaat ctctgagcca ttttcttggc
     6481 tatagccagg atgaattacg cacgatgaca tttcagcaat tgacctggcc ggaagacctg
     6541 aataacgacc ttgaacagct aaacatgctg gtgcgcggcg acatcaacag ctattccatg
     6601 gaaaaacgct actacacccg caacggcgat gtcgtctggg cgctgctggc cgtctcgctg
     6661 gttcgtcata aagacaatca acctctctat tttattgctc agattgaaga tattaacgat
     6721 ctcaagcaaa gcgagcagga aaaccagcgg ttgatggagc gtattacaca ggcgaacgag
     6781 gcgctgtttc aggaaaaaga acggttgcac atcacgcttg actctatcgg agaagcggtg
     6841 gtgtgtattg atgtcgcgat gaatatcacc tttatgaatc cgatcgccga gaagatgagc
     6901 ggctggcggc aagaggatgc tttaggcgcg ccattattaa cggttctgcg cattacgtca
     6961 ggtaataagg ggccgctgct ggaggatatt tatcgcgcca acaggtcgcg atcggacatg
     7021 gaacaggaga tagtgctcca ttgtcataac ggcggtagct acgatattca ttacagtatc
     7081 acgccgctca gtacgcttga cggcgataag attggttcgg ttctggttat ccaggacgtt
     7141 accgaatcac gaaaaatgtt acgccagctc agctacagcg caacgcatga cgccctcacc
     7201 caacttgcca accgcgccag ttttgaaaaa cagctgcaac agcgcctgca aacaatacag
     7261 gaatcgcctc aacatcatgc gctggtgttt atcgatctgg accgttttaa agcggttaac
     7321 gacagcgcgg gacatgccgc cggcgatgcc ttattgcgcg agctcgcgtc actgatgctc
     7381 agtatgcttc gctccggcga tctcctggcc cgcctgggtg gcgatgagtt tggcctgttg
     7441 ctaccggatt gtaatagtga cagcgcgcgc tttatcgcga cgcggcttat caacgccgtt
     7501 aatgaatatc actttatgtg ggaaggacgc ctgcatcgga tcggcgccag cgccgggatc
     7561 acaatgataa atgaacataa ctgccagctc acagaggtcg tgtctcaggc cgatattgcc
     7621 tgctacgccg cgaaaaatag cggtcgaggc cgtctgaccg tgtacgaacc gcagcacgca
     7681 ttaacctcct caaagggaat gatgccgctg gaagaacagt ggcatatgat taaaaataac
     7741 ctcctgctaa tgcttgccag aaacgtcgcg ccgccgcgta cgccggaggc caccagcttt
     7801 tggctggtct cactcaggct gtggaccagc gaaggggaag tgatggaaga gcgcgcgttc
     7861 cgggcagggt tagccgactc cgcgctgcat cacgcgcttg accgacgggt attccatgag
     7921 tttttccgcc atgcggcgac cgccgtcgcc agcaagggat taagcgttgc gctgccgctg
     7981 tccgccgcgg gattatacag cgcgaccctt attgatgagc tgctggaaca actggagcat
     8041 agcccactgc cgccacggtt attacacctg attatcccgg ctgacgttat cgttaagcag
     8101 gcgcagaccg ccgctgcgac tctgcgaaaa ctgcggcaac gcggctgcca ggtgattctc
     8161 agccatgtcg ggcgcgattt acagctgttt aatttactgc ccccgcatat cgtcgattat
     8221 ttactgctgg atagcgacct tatcgccaac gttcatgaaa gtttaatgga tgaaatgctg
     8281 acctcgatca tccagggaca cgcccagcat ctggacatca aaacgctcgc cgggccggta
     8341 caaaacccac aggtgctgga tacgctctcc cgtattggcg tggatctgat ttatggcgac
     8401 actatcgccg aagcgcaacc gctggatttg ttactgaata ccagctattt cgctatccat
     8461 tgacggttgc cagccgtggg tataccagat atgcagtagc gcgtaggaac gccacggttt
     8521 ccagcgctcc gcgtagcgac ggatctgcgc ggccgtcatc ccggcgaagc gctgcttaat
     8581 taagtaatca tcgggcaaaa agatatcttt tgcctgccaa ccgcgcaggg cgaaatagtt
     8641 cgccgtccag cggccaattc ccggaaatgt ttgtaaattt ttaacgctct gctcaatatc
     8701 cggcggcgcg gagagcgcca gttttcccgc cagcgtcgcc tgcgccagat gaatcagcgc
     8761 ttcggcgcgc cgcagcggca tccccagagc tttaagcgcc agcggatcgg ccaacgccag
     8821 cgtttccgga ccgggaaaac agacataatc gggcgcatcc ggcaacgcct cgccatagcg
     8881 gcgcgccact ttcgccgtca accttgccgc catcgcgaca ctcaccagtt gccccagtat
     8941 cgcccgcacg ccctgttcaa acgtatcaac cgatcccggt aaacgcagcc ccggtctgtc
     9001 ctcgcccagt ggccccagca cggcggcaac ctgctcgggc tggcagtcaa gatcaaacag
     9061 acgcgaaact ttcgccagac acgccggcgc gacgggaagt aatccggcgc tcacgctaac
     9121 ctgcacagtg tgggtgggca gatggggcct cacgctgacc agtccgcgat gctcgcccac
     9181 caccaggctg cgcgcataaa agccctcgcc tactgtttcc acgccgtcca ccgcacgcgc
     9241 ggcaagaaag cccaacatcc acgaccagtc gtaaggcggc tgccagctca gggtaaacat
     9301 acttttctcc tttatttgac ctttcagcat aaacgctaat cgcacgtaac gccttgcttt
     9361 catattccag ttgtcgccgc gacgacattt cgctaaagtc acgccccttc ttcactggca
     9421 tggggatttt aaggtgttta taggatttga ttacggtacg gcaaactgct cggtcgccat
     9481 tatgcgcgac gggcatccac agttgctgac aatggagaat aacagcgcat tactgccgtc
     9541 tatgctgtgt gcgccgacgc gcgaagcggt gagcgagtgg ctgtatcgcc atcatgatgt
     9601 gccggcaacg gacgaagaaa cccaggcgct gctacgccgc gctatacgct acaaccgcga
     9661 ggaagatatt gaggttggcg cgcaaagcgt acagtttggt ctggcgtcgc tggcgcacta
     9721 tattgacgat ccccaggaag tctggttcgt caaatcgccg aaatcctttt taggcgccag
     9781 cggcctgaaa ccgcagcagg tcgcgctgtt tgaagatttg gtctgcgcca tgatggtaca
     9841 tattcttcat acggcgcaca gccaattgcc ggaggccatt actcaggcgg tgatcggtcg
     9901 cccgatcaac tttcagggac tcggcggcga tgacgcgaac cgccaggcgc agggtattct
     9961 ggagcgggca gcaaaacgcg ccggttttca ggaggtggta ttccagtatg aaccggtcgc
    10021 agcgggcctg gactacgagg ctacgctgcg ggaagagaag cgtgtgctgg tcgtggatat
    10081 tggcggcggt accaccgact gttccatgct gctgatgggg ccgcagtggc gtcagcgcgc
    10141 cgatcgtgaa aacagcctgt tggggcacag cggttgccgc gtgggcggaa acgatctgga
    10201 tatcgcgctg gcctttaaaa atctgatgcc tttgctgggc atgggcggcg aaaccgaaaa
    10261 aggtatcgcc ctgccggtgc tgccgtggtg gaacgccgtc gcgattaacg acgtcccggc
    10321 gcaaagcgat ttttacagta gcgcgaatgg tcgtctgttg aacgatttgg ttcgcaacgc
    10381 gcgtgaagca gacaaggtcg cgttgctgct caaggtctgg cgtcagcggc ttagctaccg
    10441 cctggtacgc tgcgcggaag agagcaaaat cgccctttcc ggccaggcgg atgttacggc
    10501 gaggctgcca tttatcagcg acgacctggc ggtcgctatc agccagcaag gactggaagc
    10561 ggcgctggat caaccgctgg cgcgtattct ggaacaggtg caactggcgc tggacagcgc
    10621 gcaggaaaaa ccggatgtca tctatctgac cggcggcagc gcccgttcgc cattgattaa
    10681 aaaagcgctt tccgaacagc taccgggcat acccgtcgct ggcggcgatg atttcggctc
    10741 cgtcaccgca ggactggcgc gctgggcgga ggtcgttttc cgctaagcgc ctcgcaagcc
    10801 cagcgctgat ggattgacat tattcttgat gtggcttaac gtcaggagtg agggtaaggg
    10861 aggattcctc ctccccctgg tgtcttagta agctggtagg ctaatcacta agagtatcac
    10921 cattatgatg actaccttca tcataaccct ttccttattt tggccccttc ctcgggaggg
    10981 gctttcccgt ttcagcatcc tgctgaaatc ggtggcttat cttcattgcc gtgccggcac
    11041 tttaccgcac tccggcgcgt taacgatttt caccgatgag agttgcgtag cgcctcgcaa
    11101 agcgggtcgc cattcagaat aatcccgacc gtgttccata attcctccat ttttctccct
    11161 tccctgctga ctacaataga ggaagcaaca ttccgcaaaa cgtttcagga tgagaaactt
    11221 ataccgatga aaggcagtaa tactttccgc tgggcaatag cgattggggt tgtagtggcc
    11281 gccgccgcat tctggttctg gcatagccgt agcgaaagcc cgaccgccgc gccgggcgtc
    11341 gccgcgcaag cgcagcatac cgccgccgca ggtcgccgcg gtatgcgcga cggccctctg
    11401 gcgccggtac aggccgcgac cgcgaccaca caggctgtac cgcgctatct gagcgggctg
    11461 ggtaccgtga ccgcagcgaa taccgttacg gtgcgtagcc gcgtggatgg tcaactcatc
    11521 gccctgcact ttcaggaagg tcagcaggtt aacgcaggcg atctgctggc gcaaatcgat
    11581 cccagccagt ttaaggtcgc cctggcgcag gctcagggac agttagcgaa agataacgct
    11641 acgttggcga atgcgcgtcg tgatctggcg cgctatcagc aactggccaa aaccaatctg
    11701 gtttcccgtc aggaactgga tgcgcaacag gcgctggtca acgaaaccca gggaaccatt
    11761 aaagcggatg aagccaatgt cgccagcgcg cagctacagc tcgactggag tcgtatcaca
    11821 gccccggtct cgggacgcgt gggtctgaaa caggtggatg tcggcaacca gatttccagc
    11881 agcgataccg caggtattgt cgtcattacg caaacgcacc cgattgatct catttttact
    11941 ctgccggaaa gcgatatcgc gaccgtggtt caggcacaga aagcggggaa aacgctggtc
    12001 gtagaagcct gggatcgaac taactcgcac aaattgagcg aaggcgtgtt gctcagtctg
    12061 gacaaccaga ttgatcccac gacgggaacg atcaaaatta aagcgcgctt taccaatcag
    12121 gacgatacgc tgttccccaa tcaatttgtg aacgcccgga tgctggtcga taccgaacaa
    12181 aatgccgttg tggtgcctgc cgcggcggtg caaatgggca atgagggcca ctttgtgtgg
    12241 gtgctgaacg acgaaaataa cgtcagcaag aagcgggtaa aaatcggtat tcaggataac
    12301 cgaaacgtgg tgatcagcgc aggattgtcg gcaggcgatc gcgtcgttac cgatggtatt
    12361 gatcggctga cggaaggcgc aaaagtcgag gtcgttgagc cgcaaaccac catggcggat
    12421 gaaaaatccc cttcccgcca tgaaggtcaa aaaggagcgc gcgcctgatg caggtattac
    12481 ctccgggcag cacgggcggc ccttcgcgtc tgtttattct gcgccccgtg gccaccactc
    12541 tgctgatggc ggcgatttta ctcgccggga ttatcggcta tcgcttcctg cccgtcgccg
    12601 ctttgccgga ggtcgactac cccactattc aggtggttac gctctaccct ggcgccagcc
    12661 cggatgtcat gacctcctcc gtcaccgcgc cgcttgagcg ccagttcggc cagatgtcag
    12721 gacttaagca gatgtcgtcg caaagctccg gcggcgcatc ggtggtgacg ctacagtttc
    12781 agttgacgct gccgctggac gttgccgagc aggaagtaca ggcggcgatt aacgcagcca
    12841 ccaatttatt gccttccgac ctgccgaatc cgccgattta tagcaaagtc aatccggcgg
    12901 acccgccgat tatgacgctt gccgtcacct caaacgcgat gccgatgacc caggtagagg
    12961 acatggtaga aacccgcgtg gcgcagaaga tctcacaggt ctccggcgtc gggctggtga
    13021 cgcttgccgg cgggcagcgc cctgcggtac gcgtaaaact gaatgctcag gctatcgccg
    13081 cgctcggtct gaccagcgaa acagtccgta ccgcaattac cggcgccaac gtcaactcgg
    13141 cgaaaggcag tctggatggc cccgaacggg cggtgacgct ttctgctaac gatcagatgc
    13201 agtctgccga cgaataccgc aagcttatca tcgcgtatca aaacggcgcg ccggtacggc
    13261 tgggcgatgt cgccaccgtc gaacaggggg cggaaaatag ctggctcggc gcatgggcga
    13321 atcaagctcc ggctatcgtg atgaacgttc aacgccagcc cggcgccaat atcattgcga
    13381 cagcggacag cattcgccag atgctgcccc agcttaccga aagcctgccg aaatcggtga
    13441 aggtcacggt cctgtccgat cgcaccacca atattcgcgc ttccgtgcgc gatacccagt
    13501 ttgaactgat gctggcgatc gcgctggtcg tcatgattat ctatctgttt ttacgtaata
    13561 ttcccgccac aattattccc ggcgtcgccg taccgctgtc gcttatcggc acctttgcag
    13621 tgatggtgtt tttggatttt tccattaata acctgacgct gatggcgctc actatcgcca
    13681 cgggtttcgt ggtggacgat gcgattgtgg tgatcgagaa catctcgcgc tacatcgaaa
    13741 aaggagaaaa accgctggcg gcggcgctca aaggcgcggg cgaaatcggc tttaccatta
    13801 tttccctcac cttttccctg attgcggtac tgatcccgtt gctctttatg ggcgatattg
    13861 ttggtcgact gttccgcgaa tttgcggtga cgttggcggt agcgatttta atctccgccg
    13921 tcgtctcttt gacgcttacg cccatgatgt gcgcgcgtat gctcagccgg cagtctctgc
    13981 gtaaacaaaa ccgcttttcc cgcgcctgcg agcggatgtt tgaccgcgtg atcgccagct
    14041 acggacgcgg attagcgaaa gtgctcaacc atccatggct tacattgagc gtggcattcg
    14101 ccacgctcct gctcagcgtt atgctgtgga taaccatccc gaaagggttc tttccggtac
    14161 aggataacgg cattatccag gggacgctgc aggcgccaca atcatcatcg tatgccagta
    14221 tggcgcaacg tcagcgccag gtggcggagc ggatattaca ggacccggcg gtgcaaagcc
    14281 tgacgacttt tgttggcgta gacggcgcta atcccacgct gaatagcgcg cgcctgcaaa
    14341 ttaacctcaa gccgctggat gcgcgtgatg accgcgtgca gcaggtgatc tcccggctgc
    14401 aaaccgccgt ggcgacgatt cccggcgtgg cgctgtatct ccagccgacg caggatttaa
    14461 ccatcgacac gcaggtcagc cgcacgcagt atcagtttac cctgcaggcc acgacgctcg
    14521 atgcgctcag ccactgggtg ccaaaactgc agaacgcgct acagtcgtta ccacagctct
    14581 ctgaggtaag cagcgactgg caagatcggg gattagcggc ctgggtgaat gtcgaccgcg
    14641 acagcgccag ccgtctgggt atcagcatgg cggatgtgga taacgcgctc tacaacgcgt
    14701 tcggacaacg cctgatttca acgatttata cccaggcgaa ccagtaccgc gtcgtgctgg
    14761 aacataatac cgccagcacg ccgggtctgg cggcgctgga gacgattcgc ctgacgagcc
    14821 gcgacggcgg caccgtaccg ctcagcgcga ttgcccgcat tgagcagcgc ttcgccccgc
    14881 tctccatcaa tcatttagat cagttcccgg ttacgacatt ttcgtttaac gtgccggagg
    14941 gctattcgct cggcgatgcg gtgcaggcga ttctcgatac ggaaaaaacg ctcgccctgc
    15001 cagcggatat tacaacgcag tttcagggca gtacgctcgc cttccaggcg gcgctgggca
    15061 gcaccgtctg gcttattgtc gccgccgtgg tggcgatgta tatcgtgctt ggcgtgctgt
    15121 atgagagttt tatccatccg attacgattc tctcaacgct gcctacggcg ggcgtcggcg
    15181 cgctgctggc gctgatcatc gctggtagcg agctcgatat tatcgccatt atcggcatta
    15241 ttttactgat cggtatcgtg aagaaaaacg ccatcatgat gattgacttc gccctcgccg
    15301 ccgaacgcga acaggggatg agtccgcgcg acgctatctt ccaggcctgt ctgctgcgtt
    15361 ttcgaccgat tctgatgacc acgctggcgg cgttgctcgg ggcattgcca ttaatgttga
    15421 gtaccggcgt tggcgcggaa ttacgtcgcc cgttggggat cgcgatggtg ggcggcttac
    15481 tggtcagcca ggtattaact ctgtttacca ctccggtgat ttatctcctg tttgaccgcc
    15541 tgtcgctgta cgtgaaaagt cgctttccgc gccataaaga ggaggcgtag atgcgctttt
    15601 tcgccctttt catctaccgc ccggtcgcca ccattttgat tgccgccgcc attacgctgt
    15661 gcggcattct gggctttcgt ctgctgccgg tcgccccgct gccgcaggtc gatttcccag
    15721 tgattatggt tagcgcctcg ctgccgggcg cctcgccgga aaccatggct tcgtcggtgg
    15781 cgacgccgtt ggaacgttct ttgggacgca ttgcaggcgt caatgaaatg acttccagca
    15841 gctcgctcgg cagtacgcgc attattctcg aatttaattt cgatcgcgat attaacggcg
    15901 cggcgcgcga cgtgcaggcc gccattaacg ccgcgcaaag cttgttgcca ggcggaatgc
    15961 ccagccgccc gacttatcgc aaggccaacc cgtccgacgc gccgattatg attttaacgc
    16021 tcacctcaga gagctggtca cagggcaaac tgtatgattt cgcctctacc caactggcgc
    16081 aaaccatcgc gcaaattgac ggcgttggcg acgttgacgt cggcggcagc tccctgcccg
    16141 cagtacgtgt aggcttaaac ccgcaggcgc tctttaacca gggcgtctcg ctggatgagg
    16201 tccgcgaagc gatcgacagc gccaacgtac gccgaccgca aggcgcaatt gaagatagcg
    16261 tccaccgctg gcaaatccag accaacgacg aactgaaaac cgccgccgaa tatcagccgc
    16321 tgattattca ctataacaac ggcgcggcgg tacgcctggg tgacgtcgcc agcgtcaccg
    16381 actcggtgca ggatgtccgt aacgccggga tgacgaacgc taaacccgct attttgttga
    16441 tgatccgcaa gctgccggag gccaacatta ttcagacggt cgacggcatc cgggcaaaac
    16501 tgccggaact gcgggcaatg atccccgccg ctatcgattt acaaatcgcc caggatcgtt
    16561 cgccgacgat tcgcgcatcg ctgcaagagg tagaagagac gctggctatc tctgtcgcgc
    16621 tggtgatcct ggtggtgttt ttattcctgc gttccgggcg cgccacgcta atccccgccg
    16681 tcgccgttcc cgtttcgctc atcggcacct tcgccgccat gtatctgtgc ggcttcagcc
    16741 tcaacaatct gtcgctgatg gcgctgacta tcgcgaccgg atttgtcgtt gatgatgcca
    16801 ttgtggtgct ggaaaatatc gcccgccatc tggaggcgag aatgaaacct ttgcaggcgg
    16861 cattacaggg tacgcgggaa gtcgggttta cggtcatctc catgagtctg tcgctggtgg
    16921 cggtatttct gccgctgctg ttaatgggcg gcctgccagg acgattatta cgggaattcg
    16981 ccgttaccct ctcggtggcg attggcattt cgctggtggt ctcgctcaca ctgacgccga
    17041 tgatgtgcgg ctggatgctt aaatcaagca aaccgcgcac ccaaccgcgt aaacggggcg
    17101 ttggccgttt gctggtcgcc ttgcaacagg gttacggcac gtcgttaaaa tgggtgctta
    17161 accatacgcg tcttgtcggt gtggtttttc ttggcaccgt tgcgctgaac atctggcttt
    17221 atatcgccat ccctaaaaca ttctttccgg agcaggacac cggcgtgttg atgggcggta
    17281 ttcaggctga ccagagcatc tctttccaag ccatgcgcgg caagctgcag gattttatga
    17341 aaattattcg cgacgatccg gcggtgaata atgtcactgg ttttaccggc ggatcgaggg
    17401 tgaatagcgg catgatgttt attacgctga agccgcgcgg cgaacgcaaa gagacggcgc
    17461 agcaagtcat tgaccgactg cgggtcaaac tggcaaaaga acccggcgcc aagctgtttc
    17521 tgatggcggt acaggatatt cgcgtcggcg ggcggcaggc taacgccagt taccaatata
    17581 cgttgctgtc tgactccctg ccggcgctgc gcgagtggga gccgaaaata cgcaaagcgc
    17641 tctcggccct gccgcaactg gcggacgtaa actccgacca gcaggataac ggcgcggaga
    17701 tgaaccttat ctacgaccgc gacaccatgt cacggctggg cattgatgtt caggccgcaa
    17761 acagcctgtt aaataacgct ttcggccagc ggcaaatttc caccatttat cagccgatga
    17821 accagtataa agtggtgatg gaagtcgatc cgcgctatag ccaggatatc agcgcgctgg
    17881 agaaaatgtt cgttatcaac cgcgacggaa aagcgattcc tctctcttat ttcgcccaat
    17941 ggcggcccgc caatgcgccg ctgtcggtaa accatcaggg actttccgca gcgtccacga
    18001 ttgcctttaa cttgccgacc ggcacatcgt tatcgcaggc gacggaggcc attgatcgca
    18061 ccatgacgca gcttggcgtc ccctcgacgg tacgcggcag tttttccgga acggcgcaag
    18121 tcttccagca gaccatgaat tcacagctta ttttgatagt ggcggcgatc gctaccgtct
    18181 acattgtgct ggggatactg tacgaaagct acgtccatcc gctgaccatt ctctctactc
    18241 tgccatcggc gggcgttggg gcgcttctgg cgctggaact cttcaatgcc cctttcagcc
    18301 taatcgccct gatagggatc atgctattaa ttggcattgt gaagaaaaac gccattatga
    18361 tggtcgattt tgcgcttgaa gcgcaacgaa gcggcggcct gacaccggaa caagccattt
    18421 tccaggcctg cttgttacgc ttccgtccaa taatgatgac cacgctggcg gcgctgttcg
    18481 gcgcactgcc attggtgtta tctggcggag acggttcgga attacggcag ccgctgggga
    18541 taaccattgt cggcggtttg gtcatgagcc agctcctgac gctctatacc acgccggtgg
    18601 tgtacctctt tttcgaccgt ctgcggctgc gtttttcgcg taaaaatagc aaaccggtag
    18661 tagagatatg acagaatttc ctgacaacac ccgctggcaa ctctggattg tggcattcgg
    18721 cttttttatg cagtcgctgg ataccaccat cgtcaacact gcgctgcctt ccatggcgaa
    18781 aagcctgggg gaaagcccgc tgcatatgca catggtagtg gtgtcatatg ttctcaccgt
    18841 cgccgtgatg ctccccgcca gcggctggct ggcagacaaa atcggcgtgc gtaatatttt
    18901 ctttgccgcc atcgtgctgt tcacgctggg ttcgctgttt tgcgccctct ccggtacgct
    18961 taatcaactg gtattagcgc gagttttaca aggcgtaggc ggcgcgatga tggtgccggt
    19021 cggacgcctg acggtcatga aaatcgtgcc gcgtgcgcaa tatatggcgg cgatgacctt
    19081 cgtcgcccta ccgggacaga tcgggccgtt actcggcccc gcgctgggcg gggtgctggt
    19141 ggaatatgct tcatggcact ggatctttct gatcaatatc ccggtgggaa ttgtcggcgc
    19201 tatggcgacc tttatgctga tgccaaacta caccatagag acccggcgct ttgatctgcc
    19261 ggggttcctg ctgttagcta tcggcatggc ggtactcacg ctggcgctgg acggtagtaa
    19321 aagcatgggg atttcgccct ggacattagc cggacttgct gcgggtggcg cggcagccat
    19381 tctgctctat ctcttccatg ccaaaaaaaa ctcaggtgcg ttattcagcc tgcgattgtt
    19441 ccgcacgccc acgttttcac tggggttgct gggcagtttt gccgggcgta tcggcagcgg
    19501 tatgctgccg tttatgacgc cggtcttttt acaaattggt cttggttttt caccgtttca
    19561 tgccggtttg atgatgatcc ccatggtgct gggcagcatg ggaatgaagc ggattgtggt
    19621 gcagatagtt aaccgttttg gctatcgtcg ggttctggta gcgaccacgc tcggactggc
    19681 attggttagc ctgttgttta tgtcggtcgc gctgctcggc tggtattatc tcctgccgct
    19741 ggtactgctt ttgcagggaa tggtgaactc ggcgcgcttt tcttccatga ataccttaac
    19801 gctaaaagac cttcccgata cgctggccag cagcggcaat agcttattat cgatgattat
    19861 gcagctctcg atgagtattg gcgtcactat tgccggaatg ctgctgggta tgtttggcca
    19921 acagcatatc gggatagaca gtagcgccac acatcacgtc tttatgtaca cctggttatg
    19981 tatggcggtt attatcgcgc taccggcgat aatttttgcc cgcgtgccga acgatacaca
    20041 gcaaaacatg gtcatttcac ggcgtaaaag gagcctgtaa tgaaagtctg gcggcccgga
    20101 atcaccggca agctgtttct ggcgattttc gccacctgca tcgtgctgct gatcagtatg
    20161 cattgggccg tgcgcgtcag ttttgaacgc ggatttattg actatatcaa acacggcaac
    20221 gagcagcggc tacaaatgct gggcgatgcg ctgggcgacc agtaccagca acacggcaac
    20281 tggcgttttt tacgtaacaa tgatcgcttc gttttccaga ttctgcgttc atttgagcat
    20341 gacaacgacc gggataaacc cggccccggt atgccgccgc acggttggcg cacccagttc
    20401 tgggtcgtcg atcaaaatgg ccgggtgctg gtcggcccac gcggtccggt gccgcatgac
    20461 ggtactcgcc gccccattct ggttaatggc gtcgaagtag gcgcgattat cgcctctcct
    20521 gtcgagcggc tgacgcgcaa tacggatatt aattttgata tgcagcagcg gcgtgccagt
    20581 tggatgatcg tggcgttatc aaccttgctg gccgcgctgg cgacgttttt gctggcgcgt
    20641 ggcctgctcg ccccggtcaa acggttggtc gagggtacgc acaggctggc ggcgggggat
    20701 tttaccacgc gcgtgacccc aaccagcgcc gatgagctgg gaaaactggc gcaagacttt
    20761 aaccagcttg ccagcacgct ggaaaaaaat cagcagatgc gccgcgactt tatggcggat
    20821 atttcccacg aactgcgcac gccgctggcg gtattgcgcg gcgaactgga agccattcag
    20881 gatggcgttc gccagttcac gccagaatcg gttacctcgc tacaggcgga agtcggtacg
    20941 cttaccaaac tggttgacga cctgcatcag ctgtcgttgt ctgacgaggg cgcgctggct
    21001 taccaaaaaa cgaccgtcga tcttgttccc cagttggaag tcgctggcgg cgcgtttaga
    21061 gaacgcttta ccagccgggg gctaacgcta cattacgcgt tgccggatag tatgaccgtc
    21121 ttcggcgacc cggatcgcct gatgcaactg tttaataatc tactggaaaa cagtctgcgc
    21181 tacaccgaca gcggcggcgg cctgcatatt tccgccgaac aacgcgacaa atcattattc
    21241 ctgacctttg ccgattctgc accgggcgtc agcgatgagc agttacaaaa gctttttgac
    21301 cgtttttacc gcacggaagt gtcccgtaac cgcgccagcg gcggttctgg actggggctg
    21361 gcgatatgcg tcaatattgt acacgcgcat aacggtcatc ttcacgccgc tcattcgcct
    21421 tttggcgggg ttagcattac agtagagtta ccgctggatc gcgatttaca gagagaagta
    21481 tgactgaatt acccattgat gaaaacacgc cgcgcatttt gattgttgaa gatgaaccca
    21541 agctgggaca gctgcttatt gactacttac gcgcggcgag ttacgccccc acgctcatca
    21601 atcatggcga caaggtactg ccgtatgtgc gtcaaacgcc gccggatctg atcctgctgg
    21661 atctgatgct gccgggtatc gatggtctga cgctatgccg ggagattcgc cgtttttccg
    21721 acatccccat tgtgatggtc acggccaaaa ttgaagagat cgaccggctg cttgggctgg
    21781 aaatcggcgc cgatgattat atctgtaagc cttacagccc acgcgaagtc gtggcccgcg
    21841 tgaaaaccat tttgcgccgc tgtaaaccgc agcgcgaact ccagcagcag gatgccgaaa
    21901 gcccgttaat gattgatgaa agccgctttc aggcctcctg gtgtggtaaa gcgctggatt
    21961 taacccccgc tgaattccgt ctgctaaaaa ccttatcgct tgaaccgggt aaagtttttt
    22021 cccgcgagca gttgttaaac cacctctacg acgactaccg tgtggtgacc gatcgtacta
    22081 tcgacagcca cattaaaaac ctgcgccgta aactggaatc gctggatgcc gaacagtcat
    22141 ttatacgcgc ggtctacggg gtgggatatc gctgggaagc ggatgcgtgt cgcctggtat
    22201 aatgattatt ggcataacaa taacaaggtc gtaagacgat attttccgcc aacgctattc
    22261 tggcggaatt aacacactgc cctctttcat ttggccgagc ggtatcccga aaaccacgac
    22321 gaacgcgatc ggggacaata aattatttgg ccgctctttt tagtttaccg atatactgtg
    22381 a
//
LOCUS       DAJVBX010000060        22218 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.060, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000060 DAJVBX010000000
VERSION     DAJVBX010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 22218)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22218)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22218
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.060"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(152..1672)
                     /locus_tag="OPV72_001947"
     CDS             complement(152..1672)
                     /locus_tag="OPV72_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HCR9914256.1"
                     /translation="MSSHPYVSQLNTPLDDDTTLMSTTDLESYITHANDTFVQVSGYQ
                     LNELLARPHNLVRHPDMPKAAFADMWYTLKQGEPWSGIVKNRRKNGDHYWVRANAVPM
                     IREGRVTGYMSIRTRATDDEIAAVEPLYQALNEGRCSKRIHKGLVVRQGLLGKLPAMP
                     VRWRVRSIMGLMAVMLALALFGTDASWQALLLGALAMLAGTALFEWQIVRPIENVATQ
                     ALKVATGERNSVQHLNRSDELGLTLRAVGQLGLMCRWLINDVSSQVSSVRNGSERLAK
                     GNNDLNEHTRQTVENVQETVTTMNQMAESVKLNSETASAADKLSMAASSAATQGGEAM
                     DTVIKTMDDIAHSTQRIGTITTLINDIAFQTNILALNAAVEAARAGEQGKGFAVVAGE
                     VRHLASRSANAANDIRKLIDASATKVQSGSEQVHAAGRTMDDIVAQVQNVTLLIARIS
                     QSTQEQTDGLSSLTRAVDELNRITQKNAALVEESAQVSAMVKHRASRLEDAVTVLH"
     gene            2102..3481
                     /gene="ygjG"
                     /locus_tag="OPV72_001948"
     CDS             2102..3481
                     /gene="ygjG"
                     /locus_tag="OPV72_001948"
                     /EC_number="2.6.1.82"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006894971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine aminotransferase"
                     /protein_id="HCR9914257.1"
                     /translation="MNRLPSSASALACSAHALNLIEKRTLNHEEMKALNREVIDYFKE
                     HVNPGFLEYRKSVTAGGDYGAVEWQAGSLNTLVDTQGQEFIDCLGGFGIFNVGHRNPV
                     VVSAVQNQLAKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGTESVEAALKL
                     AKAYQSPRGKFTFIATSGAFHGKSLGALSATAKSTFRRPFMPLLPGFRHVPFGNIDAM
                     SMAFSEGKKTGDEIAAVILEPIQGEGGVILPPQGYLTEVRKLCDEFGALMILDEVQTG
                     MGRTGKMFACEHENVQPDILCLAKALGGGVMPIGATIATEEVFSVLFDNPFLHTTTFG
                     GNPLACAAALATINVLLEQNLPAQAEQKGDTLLDGFRQLAREYPNLVHEARGKGMLMA
                     IEFVDNETGYRFASEMFRQRVLVAGTLNNAKTIRIEPPLTLTIELCEQVLKSARNALA
                     AMQVSVEEV"
     gene            3652..5669
                     /locus_tag="OPV72_001949"
                     /pseudo
     CDS             3652..5669
                     /locus_tag="OPV72_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462133.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 2,4-dienoyl-CoA reductase"
     gene            complement(5750..6886)
                     /gene="rlmG"
                     /locus_tag="OPV72_001950"
     CDS             complement(5750..6886)
                     /gene="rlmG"
                     /locus_tag="OPV72_001950"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (guanine(1835)-N(2))-methyltransferase
                     RlmG"
                     /protein_id="HCR9914258.1"
                     /translation="MSHVDDGFRSLTLKRFPQTDDVNPLLAWEAADEYLLQQLDETEI
                     RGPVLILNDTFGALSCALAEHSPYSIGDSYLSELGTRENLRHNGIAESSVTFLDSTAD
                     YPQAPGVVLIKVPKTLALLEQQLRALRKVVTAQTRIIAGAKARDIHTSTLELFEKVLG
                     PTTTTLAWKKARLINCTFSHPQLANAPQTLSWKLEDTGWTIHNHANVFSRTGLDIGAR
                     FFMQHLPENLDGEIVDLGCGNGVIGLSLLAKNPQANVVFVDESPMAVDSSRLNVETNL
                     PEAFERCEFMINNALSGVEPFRFNAVFCNPPFHQKHALTDNIAWEMFHHARRCLKING
                     ELYIVANRHLDYFHKLKKIFGNCATIATNNKFVILKAVKQGRRR"
     gene            6972..7469
                     /locus_tag="OPV72_001951"
     CDS             6972..7469
                     /locus_tag="OPV72_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HCR9914259.1"
                     /translation="MTSLTYLQGYPEHLLAQVRALIAEQRLGAVLEKRYPGAHDYATD
                     KALYHYTQELKSQFLRNAPPINKVMYDSKIHVLKNALGLHTAVSRVQGGKLKAKAEIR
                     VATVFRNAPEPFLRMIVVHELAHLKEKDHNKAFYQLCCHMEPQYHQLEFDTRLWLTHQ
                     ALSAQ"
     gene            7621..8313
                     /locus_tag="OPV72_001952"
     CDS             7621..8313
                     /locus_tag="OPV72_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin high temperature exclusion protein"
                     /protein_id="HCR9914260.1"
                     /translation="MLSQCARFIRRLCFTRRALTVACFLLVAAGVALFYSNWLIVNAS
                     QHLTWNDIQTVPARNVGLVLGAKPGNRYFTRRINTAAALYHAGKVKWLLVSGDNGKKE
                     YDEPSAMQQALIAKGVPEAAIFCDYAGFSTLDSVVRARKVFGESRITIISQAFHNQRA
                     IWLAQQYGIDAIGVNAPDLNKRHGTYTRLREKLARVSAVLDAKILHRQPKYLGAGVTI
                     GADSAHGCPSRQ"
     gene            8401..9399
                     /locus_tag="OPV72_001953"
     CDS             8401..9399
                     /locus_tag="OPV72_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCR9914261.1"
                     /translation="MIRFAVIGTNWITRQFVDAAHETGKFRLAAVYSRRLEQAQSFAN
                     DYPVEHLFTSLEAMAQSDAIEAVYIASPNSLHFSQTQRFLQHKKHVMCEKPLASNLAE
                     VDAAIACARDNQRVLFEAFKTACLPNFLLLRESLPKIGRMHKALLNYCQYSSRYQRYL
                     NGENPNTFNPAFSNGSIMDIGYYCLASAIALWGEPRSVQASANLLESGVDAHGVVVMD
                     YGDFSVTLQHSKVSDSVLASEIQGERGSLVIEKLSECQKVCFAPRGALMQDLTQPQHI
                     NTMLYEAGAFAQLIENHAVEHPGLSLSRATAKWLTEIRRQTGVIFPADDLTHPPTA"
     gene            9667..10635
                     /locus_tag="OPV72_001954"
     CDS             9667..10635
                     /locus_tag="OPV72_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family protein"
                     /protein_id="HCR9914262.1"
                     /translation="MNTVGTPLLWGGFAVVVVIMLSIDLLLQGRRGAHAMSMKQAAGW
                     SILWVTLSLLFNAAFWWYLAETQGREVADPQALAFLTGYLIEKSLAVDNVFVWLMLFS
                     YFSVPPALQRRVLVYGVLGAIVLRTIMIFAGTWLITQFEWLLYVFGAFLLFTGVKMAL
                     AKEDESGIGEKPMVRWLRGHLRMTDTIENEHFFVRKNGLLYATPLLLVLIMVEFSDVI
                     FAVDSIPAIFAVTTDPFIVLTSNLFAILGLRAMYFLLSGVAERFSMLKYGLAVILVFI
                     GIKMLIVDFYHIPIAISLGVVFGILTITLVINTWVNHQRDKKLRAQ"
     gene            10890..12134
                     /gene="sstT"
                     /locus_tag="OPV72_001955"
     CDS             10890..12134
                     /gene="sstT"
                     /locus_tag="OPV72_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HCR9914263.1"
                     /translation="MATQRASGLLQRLAQGSLVKQILVGLVLGILLAWISKPVAEAVG
                     LLGTLFVGALKAVAPVLVLMLVMASIANHQHGQKTNIRPILFLYLLGTFSAALAAVVF
                     SFAFPSTLHLSSSAQDIVPPSGIVEVLRGLLMSMVSNPIDALLNANYIGILVWAVGLG
                     FALRHGNETTKNLVNDMSNAVTFMVKLVIRFAPVGIFGLVSSTLATTGFSTLWGYAHL
                     LVVLIGCMLLVALVVNPLLVFWKIRRNPYPLVFACLRESGVYAFFTRSSAANIPVNMA
                     LCEKLNLDRDTYSVSIPLGATINMAGAAITITVLTLAAVHTLGVPVDLPTALLLSVVA
                     SLCACGASGVAGGSLLLIPLACNMFGIPNDIAMQVVAVGFIIGVLQDSCETALNSSTD
                     VLFTAAACQAEDERLANNALRS"
     gene            12584..13246
                     /locus_tag="OPV72_001956"
     CDS             12584..13246
                     /locus_tag="OPV72_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HCR9914264.1"
                     /translation="MELLTQLLNALWAQDFETLANPSMIGMLYFVLFMILFLENGLLP
                     AAFLPGDSLLILVGVLIAKGAMGFPQTILLLTVAASLGCWVSYIQGRWLGNTRTVQNW
                     LSHLPAHYHQRAHHLFHKHGLSALLIGRFIAFVRTLLPTIAGISGLNNARFQFFNWMS
                     GLLWVLILTSLGYLLGKTPVFMKYEDQLMSCLMLLPVVLLFFGLAGSLVMLWKKKYGS
                     RG"
     gene            13250..13633
                     /gene="mzrA"
                     /locus_tag="OPV72_001957"
     CDS             13250..13633
                     /gene="mzrA"
                     /locus_tag="OPV72_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EnvZ/OmpR regulon moderator MzrA"
                     /protein_id="HCR9914265.1"
                     /translation="MLKPRITARQLIWISAFLLMLTILMMTWSTLRQQESTLAIRAVN
                     QGASMPDGFSVLHHLDANGIHFKSITPKNDMLLITFDSPAQSAAAKTVLDQTLPHGYV
                     VAQQDDDNETVQWLSRLRESSHRFG"
     gene            13778..14146
                     /locus_tag="OPV72_001958"
     CDS             13778..14146
                     /locus_tag="OPV72_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1090 domain-containing protein"
                     /protein_id="HCR9914266.1"
                     /translation="MKYRIALAITLFTLSAGSYANSLCQEKEQDIQKEISYAEKHNNQ
                     RRIEGLNKALSEVRANCTDSKLRAEHQKKIAEQKEEVAERQRDLAEAKAKGDADKIDK
                     RERKLAEAQDELKKLEARDY"
     gene            14188..14493
                     /locus_tag="OPV72_001959"
     CDS             14188..14493
                     /locus_tag="OPV72_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF883 domain-containing protein"
                     /protein_id="HCR9914267.1"
                     /translation="MSKDNTTEHLRAELKSLTDTLEEVLSSSGEKSKEELSKIRSKAE
                     RALKESRYRLGETGDVIAKQTRVAAARADDYVRENPWTGVGIGAAVGLVLGVLLTRR"
     gene            14496..14894
                     /locus_tag="OPV72_001960"
     CDS             14496..14894
                     /locus_tag="OPV72_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HCR9914268.1"
                     /translation="MADSRQAQGPGKSVLGIGQRIVTIIVEMVETRLRLAVVELEEEK
                     ANLFQLLLMVGLTMLFAAFGLMSLMVLVIWAIDPQYRLNAMIATTVVLLVLALIGGIW
                     TLRKARQSTLLRHTRHELANDRQILEDDQS"
     gene            14891..15190
                     /locus_tag="OPV72_001961"
     CDS             14891..15190
                     /locus_tag="OPV72_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqjK-like family protein"
                     /protein_id="HCR9914269.1"
                     /translation="MSSKGEREKRKALLLSQIQQQRLDLSASRRDWLETTGAYDRGWN
                     TVLSLRSWALVGSSVMAIWTIRHPNMLVRWAKRGLGIWSAWRLVKTTLRQQQLRG"
     gene            15438..15830
                     /locus_tag="OPV72_001962"
     CDS             15438..15830
                     /locus_tag="OPV72_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008503138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DoxX family protein"
                     /protein_id="HCR9914270.1"
                     /translation="MKKLEDIGVLIARILMPVLFITAGWGKISGYAGTQQYMEAMGVP
                     GFLLPLTILLEFGGGLAILLGFLTRTTALFTAGFTLLTALIFHSNFAEGVNSLMFMKN
                     LTIAGGFLLLALTGPGAFSLDRLLNKKW"
     gene            15898..16884
                     /locus_tag="OPV72_001963"
     CDS             15898..16884
                     /locus_tag="OPV72_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase family protein"
                     /protein_id="HCR9914271.1"
                     /translation="MGQLIDGVWHDTWYDTKSSGGKFQRSASAFRNWLTADGAPGPSG
                     EGGFAAEKDRYHLYVSLACPWAHRTLIFRKLKGLEPFIPVSVVNPLMLENGWTFDDTF
                     PAATGDTLYQHEFLYQLYLHADPHYSGRVTVPVLWDKKNHTIVSNESAEIIRMFNSAF
                     DGLGAKAGDYYPPALQSKIDELNGWIYDNVNNGVYKAGFATSQQAYDEAVEKVFTALA
                     RLEQILGQHRYLTGNQLTEADIRLWTTLVRFDPVYVTHFKCDKYRISDYLNLYGFLRD
                     IYQIPGIAETVNMDHIRHHYFRSHKTINPTGIISVGPWQDLLEPHGHDVRFG"
     gene            17008..17373
                     /locus_tag="OPV72_001964"
     CDS             17008..17373
                     /locus_tag="OPV72_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF805 domain-containing protein"
                     /protein_id="HCR9914272.1"
                     /translation="MDWYLKVLKNYLGFGGRARRKEYWMFILVNIIFTFVLGLLDAML
                     GWQRAGGEGVLTTIYGVLIFLPWWAVQFRRLHDTDRSAWWLLLLLIPIIGWLIIIAFN
                     CQNGTPGDNRFGPDPKRFS"
     gene            complement(17412..18308)
                     /gene="yhaJ"
                     /locus_tag="OPV72_001965"
     CDS             complement(17412..18308)
                     /gene="yhaJ"
                     /locus_tag="OPV72_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator YhaJ"
                     /protein_id="HCR9914273.1"
                     /translation="MAKERALTLEALRVMDAIDRRGSFAAAADELGRVPSALSYTMQK
                     LEEELDVVLFDRSGHRTKFTNVGRMLLERGRVLLEAADKLTTDAEALARGWETHLTLV
                     TEALVPTPAFFPLIDRLAAKANTQLSLITEVLAGAWERLEQGRADIVIAPDMHFRSSS
                     EINSRKLYTLMNVYVAAPDHSIHQEPEPLSEVTRVKYRGVAVADTARERPVLTVQLLD
                     KQPRLTVSTIEDKRQALLAGLGVATMPYSMVEQDIAEGRLRVVSPESTSEIDIIMAWR
                     RDSMGEAKAWCLREIPKLFAGK"
     gene            18413..19114
                     /locus_tag="OPV72_001966"
     CDS             18413..19114
                     /locus_tag="OPV72_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pirin family protein"
                     /protein_id="HCR9914274.1"
                     /translation="MITTRTAKQCGQADYGWLQARYTFSFGHYFDPTLLGYASLRVLN
                     QEVLAPGASFQPRTYPKVDILNLILDGEAEYRDSDGNHVQAKAGEALLLAAQPGISYS
                     EHNLSKVKPLTRMQLWLDACPERENALVQKIPLSTAQQQLLASPDGEQNSLQLRQQVW
                     VHHITLEKGESLNFQLHGPRAYLQSIHGTFHAMTHNEEREALTCGDGAFIRDEPNITL
                     VADTPLRALLVDLPV"
     gene            19138..19302
                     /locus_tag="OPV72_001967"
     CDS             19138..19302
                     /locus_tag="OPV72_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914275.1"
                     /translation="MSKKSAKKRQPVVKPAVQEAMSAAVPLGYEEMLTELEAIVADAE
                     ARLAEEEAAA"
     gene            complement(19415..20725)
                     /locus_tag="OPV72_001968"
     CDS             complement(19415..20725)
                     /locus_tag="OPV72_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine dehydratase subunit alpha family protein"
                     /protein_id="HCR9914276.1"
                     /translation="MFESKINPLWQSFILAVQEEVKPALGCTEPISLALAAAAAAAEL
                     DGTVERIDAWVSPNLMKNGMGVTVPGTGMVGLPIAAALGALGGDAKAGLEVLKDASAK
                     AVADAKAMLAAGHVAVMLQEPCNDILFSRAKVYSGDSWACVTIVGDHTNIVRIETDKG
                     VVFTQADNAQEEEKTSPLGVLSHTSLEEILAFVNAVPFDAIRFILDAARLNGALSQEG
                     LRGSWGLHIGSTLAKQCDRGLLAKDLSTAILIRTSAASDARMGGATLPAMSNSGSGNQ
                     GITATVPVMVVAEHVGADDECLARALMLSHLSAIYIHHQLPRLSALCAATTAAMGAAA
                     GMAWLIDGRYDTIAMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDT
                     AVTGNEGIVAHNVEQSISNLCSLACRSMQQTDKQIIEIMASKAH"
     gene            complement(20751..21703)
                     /locus_tag="OPV72_001969"
                     /pseudo
     CDS             complement(20751..21703)
                     /locus_tag="OPV72_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004985932.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation protein"
     gene            complement(21803..22081)
                     /locus_tag="OPV72_001970"
                     /pseudo
     CDS             complement(21803..22081)
                     /locus_tag="OPV72_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004985905.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         5166 a         6031 c         5760 g         5261 t
ORIGIN      
        1 gggagaagga ataaatatca cattattttt aacatcacag gccactggta ctctctatga
       61 tggcaggcac cgccttctat cagagcacat ccgcccggta agcttgttgc taccgggcgg
      121 atgtcattac cgttgctacc tacaaataaa cttaatgcag taccgtgacc gcatcctcca
      181 gccggctggc acggtgtttt accatcgcgg agacttgtgc gctctcttcc accagcgccg
      241 cattcttctg ggttatgcgg ttcaactcgt ccacggcgcg agtcaggctg gaaagcccat
      301 ctgtctgttc ctgcgtcgac tggctgatcc gtgcgataag cagggtgaca ttttgcacct
      361 gggctacaat gtcatccatg gtacggcctg cggcgtgaac ctgctcggag cctgactgca
      421 cctttgttgc gctggcatca attaatttac gaatatcgtt cgccgcgtta gcgctgcggc
      481 tggcaagatg gcgtacctcg ccagcaacca cggcaaaccc tttcccctgc tcgcccgctc
      541 tcgccgcttc taccgccgca ttcagcgcca ggatattcgt ctgaaaagcg atatcgttaa
      601 ttagcgtggt gatcgtcccg atacgttgcg tactgtgagc gatatcatcc atcgttttaa
      661 tcaccgtatc catcgcctca cctccctgag tcgccgcgct actggccgcc atggaaagct
      721 tatccgcagc ggaagccgtc tcggaattga gcttcacgga ctccgccatc tggttcatgg
      781 tcgttaccgt ttcctgaaca ttctccacgg tctgacgggt gtgttcgttc agatcattgt
      841 tacccttcgc cagcctttca ctgccgtttc tgacgctgga cacctgactt gatacgtcat
      901 tgatcagcca acggcacatc aagccaagct gccccacggc cctcagcgtc agccccaact
      961 catcgctacg attaaggtgt tgtacgctgt tgcgttcgcc ggtcgccact ttcagcgcct
     1021 gcgtcgccac attttcaatg ggacgcacaa tttgccattc aaatagcgcc gtacctgcca
     1081 gcatcgccaa cgcgcccaac aacaacgcct gccatgaggc atccgtaccg aacagcgcca
     1141 acgccagcat tacggccatt agccccataa tgctacgcac tcgccagcga acaggcatcg
     1201 cgggcagttt gcccagcaag ccctgacgaa ccaccaggcc tttatgaata cgtttactac
     1261 accgcccttc atttagcgcc tgatataaag gctcgacggc ggcaatctca tcatccgtgg
     1321 cgcgggtacg gatcgacata tatcccgtca cacgcccttc acgtatcatc ggtaccgcgt
     1381 tggcccgcac ccaataatga tcgccgtttt tacgccggtt tttcacaatg ccgctccacg
     1441 gttcgccctg ttttagggtg taccacatat ctgcgaaggc agctttcggc atatccggat
     1501 gacgcaccag attatgtggc cgcgccagta actcgtttaa ctgatagccg ctcacctgga
     1561 caaaagtgtc attggcgtga gtgatatagc tttccaggtc ggtcgtagac atcagagtgg
     1621 tatcatcatc cagcggggta tttagctggc tgacgtaggg atgagaagac atgatagcgt
     1681 cctgtgcagg ttatctggat gttaattttt cgctcagatg ttatttcggc gctaatctat
     1741 ttatctttag ttgttaaaat tgctctggat cgcaatttgc gattaatcct taatatttgt
     1801 acgattttca ccttatcctg cgccttattt tcattatgaa attgtttagc gtggacaacc
     1861 tttttcttta aaatctgccc tggctcacct ttttctcacg ccgccgctaa cgcaacacac
     1921 cgtaaaccgt aaaacaagat ctgctcaaaa tgcatccaat tgttaacgta taacattaaa
     1981 tgttgtgtaa atgtgattat tcctggtgtt tatcccgatt ttcactatgg gcttagaccc
     2041 ccgctaatcc ctgcaatact taattcagta tcatgtgata cacggccctc tggagctcat
     2101 tttgaacagg ttaccttcca gcgcatcggc tttggcctgt agcgcgcacg cactgaatct
     2161 catcgagaag cgaacgctaa accatgagga aatgaaagca ctaaaccgag aggtcattga
     2221 ctactttaaa gagcatgtaa atccaggatt tctggaatac cggaaatctg ttaccgccgg
     2281 cggggattac ggagccgtag agtggcaagc gggcagtttg aatacgcttg tcgacaccca
     2341 ggggcaggag tttatcgatt gtcttggggg gtttggcatc tttaacgtgg ggcaccgtaa
     2401 tcctgttgtg gtatccgccg tccagaatca actcgcaaaa caacctctcc acagccagga
     2461 gttacttgac cccttgcggg cgatgctggc aaaaacgctg gcggcgctaa caccggggaa
     2521 actcaagtac agctttttct gtaacagcgg caccgaatcc gtcgaagcgg cgctaaaact
     2581 ggcaaaagcg tatcagtcgc cgcgcggcaa gtttaccttt atcgccacca gcggcgcatt
     2641 tcacggcaaa tcattgggcg cgctctccgc cacggccaaa tccaccttcc gcagaccctt
     2701 tatgccttta ctgccgggct tccgccatgt gccgtttggc aatatcgacg cgatgagcat
     2761 ggcatttagc gaaggcaaaa aaacgggcga cgagatagca gccgtgattc tggagcctat
     2821 tcagggtgaa ggcggcgtga tcctgccgcc gcagggatac ctgacagagg tacgtaagct
     2881 ctgtgatgaa ttcggcgcgc tgatgattct ggatgaagta caaaccggca tggggcgtac
     2941 cggcaagatg tttgcctgcg agcacgaaaa tgtgcagcct gatattctgt gtctggcgaa
     3001 agccctgggc ggcggcgtga tgccaattgg cgccaccatc gcgactgagg aggtgttttc
     3061 ggttctgttc gacaatccct tcctgcatac caccactttt ggcggtaacc cgctggcttg
     3121 tgctgccgcg ctggcgacca ttaacgtcct gctggaacaa aacctcccgg cccaggcgga
     3181 acaaaaaggc gatacgctcc tggatggttt tcgacaactt gcgcgtgaat atcccaatct
     3241 ggtacacgag gcgcgcggca aaggtatgtt gatggccatt gaatttgtcg ataacgaaac
     3301 gggctaccgt tttgccagtg agatgttccg tcaacgcgtg ctggtcgctg gtacgctgaa
     3361 taatgcgaaa acaattcgta tcgagccacc gctcacgcta accattgaac tgtgcgaaca
     3421 ggtattgaaa tcagcgcgta atgcgctggc ggcaatgcag gtgagcgttg aagaggttta
     3481 aaaacgatgc cggatggcgc tgtgcttatc cggcctgttt tccccgggtc gcggcctctt
     3541 ttttgaatcc catcacaatc accacattcc ccttttccct tttacctcgc gacggctaca
     3601 gtagtaactc atccgaccac ataacaataa ttttacatac tggatacgct tatgagctac
     3661 ccgtcgctgt tcgccccgct cgatctgggc tttactactc tcagaaaccg tgtgctgatg
     3721 ggatcgatgc acacgggtct ggaagaacat cctgatggcg ctgagcgcct ggcggcattt
     3781 tatgccgagc gcgcgcgaca cggcgtagcg ttaatcgtca ccggcggtat tgcgcccgtt
     3841 ccctccgggg tcgtgatgac cggcggcgcg atgctgaacg atgccagcca gttaaagcct
     3901 caccgcgtgg tgaccgatgc cgtacatgcg caaggcggta aaatcgcgct gcaaattctg
     3961 cacaccggac gttacagcta tcagccgcac ctggtcgcgc cgtcggcaat tcaggcgcca
     4021 atcaaccgct ttatgccaca tgaactgacg catgatgaaa tcttgcagtt aatcgacgac
     4081 ttcgcacatt gcgcgcagct ggcgcgggaa gcaggctacg acggcgtaga ggtgatggga
     4141 tcagagggct atctgattaa tgaatttctc acgcggcgaa ctaaccatcg cgatgacgaa
     4201 tggggcggcg actataccag tcgtatgcgc ttcgcggttg aggtagtacg cgcggtacgc
     4261 cagcgggtag ggaacgactt tattattatc tatcgcctgt cgatgctcga tctggtggaa
     4321 aatggcggca cgttcgacga aacggtacaa ctggcgcaag ccattgaagc cgcaggcgca
     4381 agcctaatta ataccggcat tggctggcat gaggcgcgaa tcccgaccat cgccacgcca
     4441 gtaccgcgtg gcgcctttag ctgggtgaca cggaaactca aaggtcatgt gtcggttccg
     4501 ctgatcgcga ccaatcgcat taacgatccg caggtcgccg agacgatcct gacgcgcggc
     4561 gatgccgata tggtgtcgat ggcgcgtccc ttccttgccg atgctgaatt cctgactaaa
     4621 gcgcaatccg gacgcgcaga tgagatcaat acctgtatcg gctgtaatca ggcctgtctg
     4681 gatcggatct tcatcggcaa agtgacctcc tgtctggtga cccacgcgcc tgtcacgaaa
     4741 cccacatgcc gataacgccg gccatacgca aaaagaatct ggccgttgtc ggcgcaggcc
     4801 cggcggggct ggctttcgcg attaacgccg cgtcgcgcgg ccatcatgtc acgctgtttg
     4861 acgcccagag tgaaattggc ggtcagttta ctatcgccag gcagatcccg ggtaaagaag
     4921 agttttacga aacgctgcgc tactaccgtc gaatgatcga tgttactggc gttacgctga
     4981 aactgaacca acgggtgaac gcagaggatc ttcagccgtt tgacgaagcg atcctcgcct
     5041 gtggaatagt accgcgccgc ccgccgatag acggtatcga tcatccaaaa gtattgacct
     5101 acctggaggt attgcgcgat aaagcgccgg ttggtaagcg agtggcgatc atcggctgcg
     5161 gcgggatcgg ttttgacacg gccatgtatc tgagccagca cggcgaatcc accagccaaa
     5221 atattgctga attttgtacg gaatggggaa ttgataccag cctgcaacag gcaggcggtc
     5281 tgcgcccgga aggcccgcgc ctggcacgta gtccacggca aatcgtcatg ctgcaacgca
     5341 aagccagcaa gccgggcgaa gggttaggta aaaccaccgg ctggatccat cgcgcgacgt
     5401 tactggcgcg cggcgtgaag atgatcccgg cggtcagtta ctagaagatc gacgacgacg
     5461 gattacatct cttgatcggc ggcgaaccgc agttgctgga agtggatcat gtggtgatct
     5521 gcgccggaca ggaaccccgc cgtgaactgg cggacccgtt acgcgccgca ggtaaaacgg
     5581 tacatcttat cggcggatgc gatgtcgcga tggaactgga tgcccgacgg gcgattgccc
     5641 agggcacccg actggcgctg gagatttaac gactttgcct gatggcgctg cgcttatcgg
     5701 gcctatgccg tcataccggt tttataggcc ggtatgacgc ttgagtgcct tatcgacggc
     5761 gtccctgctt caccgctttc agaataacaa atttattgtt ggttgctatc gtcgcgcaat
     5821 taccgaaaat cttcttcagc ttgtggaaat agtccagatg gcggttcgcc acaatataca
     5881 gttcgccgtt gattttcagg cagcggcggg catgatggaa catctcccag gcgatattat
     5941 ccgtcagcgc atgtttctgg tggaacggcg gattgcagaa caccgcgtta aaacggaacg
     6001 gctccacgcc ggagagcgcg ttgttgatca taaattcgca gcgttcgaac gcttccggca
     6061 ggttcgtttc tacattcaaa cggctggaat ctaccgccat cggcgattca tcgacaaata
     6121 ccacgttcgc ctgcggattt ttcgccagta agctcaggcc aatcacccca ttgccgcagc
     6181 cgagatcgac aatctccccg tcgaggtttt ccggcaaatg ctgcataaag aagcgcgcgc
     6241 cgatatccaa tccggtacga gaaaacacat tcgcgtggtt gtgaatcgtc cagcctgtat
     6301 cttccagttt ccagcttagc gtttgcggcg cgttggccag ttgcggatga ctgaaggtac
     6361 agttaatcag gcgcgctttc ttccacgcca gcgtcgtcgt ggttgggccc agcacttttt
     6421 caaacagttc cagcgtagag gtatgaatat cacgcgcttt cgcgccggcg ataatacgcg
     6481 tttgcgccgt aacgacctta cgcaaagcgc gtaactgctg ttccagcaac gccagtgttt
     6541 tcggtacttt aatcaatacc acgcccggtg cctgcgggta gtcagcggta ctgtcgagaa
     6601 acgttacgct ggactccgcg atgccgttat ggcgtaaatt ctctcgcgta cccagttcgc
     6661 ttaaatatga atcgccaata ctgtatggcg aatgctccgc cagcgcacag cttagcgcgc
     6721 caaacgtatc attcaggatc agcaccgggc cgcgaatttc cgtctcatcc aactgttgca
     6781 gcagatactc atcggccgcc tcccacgcca gaagcgggtt aacatcatcc gtttgcggaa
     6841 aacgtttcag cgtcagtgaa cggaaaccgt cgtctacgtg gctcattagg cctcctgaat
     6901 ggtaaaattg cggcgttatc cctgaaaagg gtgcgtgagt atacactttt tatcggcaac
     6961 atggagcttt gatgacctca ctaacttacc ttcaggggta tccggaacat ctccttgccc
     7021 aggtgcgcgc cttaatcgcc gagcagcgcc tgggggcggt gctggaaaaa cgttatcccg
     7081 gcgcgcatga ttacgctact gacaaagcgc tatatcacta tactcaggaa ctgaaaagtc
     7141 agtttctgcg caatgcgccg cccatcaata aagtgatgta tgacagcaag atccatgtgc
     7201 tgaaaaatgc gctgggactg cataccgctg tctcgcgcgt tcagggcggc aagctcaagg
     7261 ccaaggcgga gatccgcgtc gccaccgtgt ttcgcaacgc cccggagcca ttcttacgaa
     7321 tgattgtggt tcacgaactg gcgcacctga aagagaaaga tcataacaaa gcgttttatc
     7381 agctctgctg ccatatggag ccgcagtacc atcaactgga atttgatacg cgcctgtggc
     7441 tgacgcatca ggcgctgtcg gcacaataaa ttctgaaaat gccccttccc ccgtatcttt
     7501 ttaacggcgt gggcataaaa tcgacgcgtt cacatttcgc tcattgcctg ccgccacctc
     7561 aaggatgacg atctgtagag ggtatttttt atccaccgcc aacggaaccg cgcaacaacc
     7621 atgctctcac aatgtgcccg ttttatccgc cgcctctgtt ttacacgccg ggcgttaaca
     7681 gtggcgtgtt ttctgcttgt cgcagcaggc gtcgcgcttt tctattccaa ctggcttatc
     7741 gtcaacgcct cacagcatct gacatggaat gacattcaga ccgttcccgc ccgcaatgtc
     7801 gggctggtat taggcgccaa acccggcaat cggtatttta cccggcggat taatactgcc
     7861 gccgcgttgt accacgccgg taaagtgaag tggctgttag tcagcggcga taacggcaaa
     7921 aaagagtacg atgaaccttc ggcgatgcag caggcgctga tagcgaaagg tgtgccggaa
     7981 gcggccattt tttgtgatta tgccggattc tccacgctgg actccgtggt tcgcgcccgg
     8041 aaagtgtttg gcgaaagccg cattacgatt atctcgcaag catttcataa tcaacgggcg
     8101 atctggctgg cgcaacaata tggcattgac gctatcggcg ttaacgcgcc ggatctgaat
     8161 aaaaggcacg gaacctacac acgacttcgg gaaaagctgg cgcgggttag cgcagtgctg
     8221 gatgccaaaa ttttgcatcg tcagcctaaa tatctgggcg ctggcgtcac tattggggct
     8281 gatagcgcac acgggtgccc ttctcgccag taaaatgcca gagtgcgtcg cagcgcactg
     8341 gcaagggcgg aaaggcgtgc tacattgacg aaaatccctt tctggagtcc gctgacgttt
     8401 atgatacgtt tcgctgtaat tgggactaac tggatcacgc gccagtttgt cgacgccgcc
     8461 catgaaaccg gcaaattcag gctcgccgcc gtttactccc gtagacttga acaggcgcag
     8521 tctttcgcaa atgattatcc cgtcgagcat ctgtttacct cgctggaagc gatggcgcaa
     8581 agcgacgcga ttgaggcggt ttatatcgcc agcccgaatt ccctgcattt ctcccagacg
     8641 cagcgctttt tgcagcataa aaaacatgtc atgtgcgaaa agccgctggc ttctaacctg
     8701 gcggaggttg atgccgctat cgcctgcgcg cgcgataatc agcgggtact gtttgaagcc
     8761 tttaaaaccg cctgcctgcc caatttcctg ctgctgcggg aatcgttgcc gaaaatcggc
     8821 agaatgcata aagcattact aaattactgc cagtactctt cacgttatca gcgctatctg
     8881 aacggtgaaa atccgaatac gtttaatccg gccttctcca atggttcgat tatggatatc
     8941 gggtattact gtctggcgtc ggcgatcgcg ctatggggcg agccgcgcag cgttcaggcg
     9001 tcggcgaatt tattggaaag cggagtagat gcacacggcg tcgtggttat ggattacggc
     9061 gattttagcg tcacgctaca gcattccaaa gtcagcgact cggtactggc cagtgaaatt
     9121 cagggcgaga ggggatcgct ggtcattgaa aagctgtcgg aatgccagaa agtgtgtttt
     9181 gcgccgcgcg gcgcgctgat gcaggatctg acccagcctc agcatattaa taccatgctg
     9241 tatgaagccg gggcgtttgc ccagcttatt gaaaaccacg ccgtggaaca tccggggttg
     9301 tcgctaagtc gcgccacggc aaaatggctg acagaaatac gccgtcaaac cggggtcatc
     9361 ttcccggcgg acgatctgac tcatccccct actgcgtaaa attatgtaaa tcgtatgtta
     9421 caggtcattg actctacgcg tggcctgtca tactttgtta cgcgcaaagg ggagtaactt
     9481 cattgccggt cgatcgtcat tacgatgtgt gcaaaaccac atccggtcac cgggcagcca
     9541 taaaggaatg cgtcagcgta ttcctttatt gttgtaagtg agaccttgcc gaatggcaag
     9601 gtctatgcat aaaagcagcg gctaatgcca ttcggcatta gccgtttttt tgcatgggga
     9661 gaaataatga atactgttgg tacgccatta ttatggggtg gattcgcggt tgttgtggtg
     9721 ataatgctat ccatcgactt gttgttgcag ggacgccgtg gcgcacatgc gatgtcgatg
     9781 aaacaagcgg caggatggtc aatcctgtgg gtaacgctct cgctactgtt taacgccgct
     9841 ttctggtggt atctggctga aacgcaaggg cgcgaagttg ctgacccgca ggcattagcg
     9901 ttccttaccg gctatctgat tgaaaagtcg ctggccgtag ataacgtctt tgtctggctg
     9961 atgctgttta gctatttctc cgtccctccg gctctgcaac gccgggtgct ggtgtatggg
    10021 gttcttggcg cgatcgtgtt gcgtactatc atgattttcg ccggtacctg gcttatcact
    10081 cagttcgaat ggctgctgta tgtgttcggc gccttcttgc tgtttaccgg cgtaaaaatg
    10141 gcgctggcga aggaagacga atccggcatt ggcgaaaaac cgatggtgcg ttggctgcgc
    10201 gggcatctgc gcatgactga tacgatcgag aacgagcact ttttcgtacg taaaaacggc
    10261 ctgctatatg ccacgccgct gctgctggtg ctgattatgg ttgagttcag cgatgtgatc
    10321 ttcgccgttg acagtattcc ggcgatcttt gcggtcacca ccgacccgtt catcgtactg
    10381 acctctaacc tgtttgccat cttaggactg cgcgcgatgt acttcctgct gtccggcgtg
    10441 gcggaacgct tctcgatgct gaaatatggt ctggcggtca ttctggtctt tatcggcatt
    10501 aagatgctga tcgtcgactt ctaccatatt cctatcgcga tttcgctggg cgtagtgttt
    10561 ggcattctga ccattacgct ggtgattaac acctgggtta accatcagcg cgataagaaa
    10621 ctacgagcgc aataatcttt tatcggggta aacctgcccc atcaaaaacg cccggcagcg
    10681 tacacctgcc gggcgttttt gtttaacatg tcacaatact gttaatataa agttataaaa
    10741 catgatcaca gcaaaaaatc caggatattt cgcttcccga accttcaact ttccttatac
    10801 tcaaccaggc aaacactttg ttacatcctg aaagatgcgc cgtaagagcg tgcaggggat
    10861 gaccagcaac acaatacaag gaatatgaaa tggctacgca acgagcatca gggctactgc
    10921 agcgtttagc gcaaggcagt ctggttaaac aaattttagt gggtctggta ctggggattt
    10981 tactggcatg gatttctaag cctgtggcag aagcggttgg cttgcttggc accctgttcg
    11041 tcggcgcctt aaaagcggtc gcccccgttc tggtgctgat gctggtaatg gcctcgatcg
    11101 ccaaccacca gcacggccaa aaaaccaata ttcgccctat tctctttctt tacctgctag
    11161 gcaccttttc agccgcgctg gcggccgttg tgttcagctt cgccttccct tcaacgctgc
    11221 atctgtccag tagcgcccag gatatcgtgc cgccgtccgg cattgtagaa gtcctgcgcg
    11281 gtctgctgat gagcatggtg tcgaacccca tcgacgcact gctgaacgct aactatatcg
    11341 ggattctggt gtgggccgtc ggtctgggat ttgccctgcg tcatggcaat gaaaccacca
    11401 aaaacctcgt gaacgatatg tctaacgccg tgacctttat ggtgaaactg gtgatccgtt
    11461 tcgcgccagt cggtattttt ggtctggttt catcaacgct tgcaaccacc ggcttctcca
    11521 ccctgtgggg ctatgcgcac ctgctggtcg tcttgattgg ctgtatgctg ctggtcgcgc
    11581 tggtggtcaa cccgctgttg gtattctgga aaattcgtcg caacccttat ccgctggtgt
    11641 tcgcctgcct gcgtgaaagc ggtgtttatg ccttctttac ccgcagttct gccgccaata
    11701 ttccagtgaa tatggcgctg tgcgaaaaac tgaatctgga cagggatact tactccgttt
    11761 ccattccgct gggtgccact atcaatatgg ccggcgcggc aattaccatt acggttctga
    11821 cgttggcggc agttcatacg ttaggcgtcc cggtggatct gcctacagcg ctgctgctga
    11881 gcgtggtggc ctcgctgtgt gcttgcggcg cctccggcgt ggcaggcggt tcattgctgc
    11941 tgatcccgct ggcgtgcaac atgtttggca tcccgaacga tatcgcgatg caggtagtag
    12001 cggtcggctt tattatcgga gtattgcagg attcgtgtga aacggcgctg aactcatcta
    12061 ccgatgttct gttcactgcg gcagcctgcc aggcagagga cgaacgtctg gcgaataacg
    12121 ccttgcgtag ctaagtgatt atcaatgccg gatggcgcgt gccatccggc gtgacgataa
    12181 atcagaatct cccaatccat aggctgtgac ggaaagcgaa ttgatgttca cgcgcgacat
    12241 cctcgcgtaa cgttatatgt agatggcgtc tgccgcagcg ctcggtcagc gtaaagtata
    12301 aagtgtcagc ctgtgtaaat cctctcgcca ccctcctttg cgataagcaa aatcaaagct
    12361 caacgacgcg taatttctat aacggacttc gttgaccttt gttacaatta gatgcatttt
    12421 gaatttttgt gtgttagtgc ttgcttactt cacaacttaa caaggaatag ttcaggccgc
    12481 gaatttgccg tttccgcaac gctgataaaa actccaactc tgttgcggca gtgcaaacct
    12541 cagatcaccg gcgtgacgtt aaccgattct ccaggaatac tgaatggaac tactgactca
    12601 attgctgaat gccctgtggg ctcaggactt tgaaacactg gccaatcctt ccatgattgg
    12661 catgttatat tttgtgttat ttatgatttt gtttctggaa aatgggctgc tccctgccgc
    12721 ctttttgcct ggcgacagcc tgttgatact ggtcggcgtg ctgatcgcca aaggcgcgat
    12781 gggttttcca caaaccattt tgctgcttac cgtcgcggcc agcctgggtt gctgggtcag
    12841 ctatatacag ggccgctggc tggggaatac ccgcaccgtg cagaattggc tctctcatct
    12901 ccccgcacat tatcatcaac gcgcccatca ccttttccat aaacacggcc tgtcggcatt
    12961 attgataggc cgttttatcg cgtttgtcag aacgctgcta cccaccattg ccggcatatc
    13021 cggcctgaat aacgcgcgct ttcagttttt caactggatg agtggcttgt tgtgggtgct
    13081 tatcctgacg tcgctgggct atctgctggg caaaacgccc gtctttatga agtatgaaga
    13141 tcagctaatg tcatgcctga tgctgctgcc cgtggtgctg ctcttttttg gcctggcggg
    13201 ttcactggtc atgctgtgga aaaagaagta tgggagccgg ggataactta tgcttaaacc
    13261 acgcataact gcccgacaac tcatttggat cagcgctttt ctgctgatgc tgaccatact
    13321 catgatgacg tggtcaacgc tgcgtcagca agagtcgacg ctggccattc gcgcggttaa
    13381 tcagggcgcc agtatgccag acggcttctc agttctgcat catctggatg cgaacggcat
    13441 tcattttaaa agcattacgc ctaaaaatga catgttgctc attaccttcg attcccctgc
    13501 gcaaagcgcc gcagcaaaaa cagtgcttga tcaaacgtta ccacacggtt atgtcgtcgc
    13561 tcagcaggac gatgacaacg aaacggtaca gtggttgtcc cgcttacggg aaagctcaca
    13621 ccgctttggc taatctccag gaatccgaat catatcactc actttggtga tttcattgtt
    13681 taatgactat gattaataaa gcggtgctta acccaccgcg ttattatcgg gatcaccgcc
    13741 ccggacaacg ggtccgaaca taagggaaag ttcaggaatg aaataccgca tcgctttggc
    13801 tatcacgctt tttacgctta gcgccggcag ctacgctaat tcgctttgtc aggaaaaaga
    13861 gcaggatata caaaaggaaa ttagctacgc tgaaaagcac aacaatcagc gccgtattga
    13921 gggtctgaac aaggcgctca gcgaagtacg cgccaattgt actgacagca agctgcgcgc
    13981 cgagcatcag aaaaagatcg ctgagcaaaa agaagaggta gccgaacgcc aacgtgattt
    14041 agccgaggca aaagcaaaag gcgatgcgga taaaatagac aaacgtgaac gtaagctggc
    14101 cgaggctcag gatgagctaa aaaaacttga ggccagagac tactaaatta acgccgaatg
    14161 taaatactca ctcacctgga gaaaactatg tcgaaagata acactacgga acatctgcgc
    14221 gctgagttga aatccctgac cgatacgctc gaagaagtgc tgagctcttc gggcgaaaag
    14281 tcgaaagaag agttgagtaa gattcgtagc aaagccgagc gcgcgctgaa agagagccgt
    14341 taccgcctgg gcgaaacggg tgatgtgatt gccaaacaga ctcgcgtcgc cgccgcccgt
    14401 gccgatgatt atgtgcgcga aaacccctgg acaggcgtag gcattggcgc cgctgtcggt
    14461 ctggtgttgg gcgtactgct gacgcgtcgt taattatggc ggactctcga caggcacaag
    14521 gaccaggcaa aagcgtactg ggtatcgggc agcggattgt caccattatc gttgagatgg
    14581 tggaaacccg gctgcgactg gcggtagtag aactggaaga agagaaagcg aacctctttc
    14641 agcttttgct gatggtaggt cttaccatgc tcttcgcggc gtttggctta atgagcctga
    14701 tggttctggt catctgggct atcgatcctc agtaccgttt gaacgcgatg atcgctacca
    14761 cagttgtact gttagtgctt gcgctaatcg gcggcatctg gactttgcgc aaagcgcgtc
    14821 agtccacgct attgcgccat acgcggcacg aactggctaa cgatcggcaa attctggagg
    14881 acgatcagtc gtgagcagca aaggcgaacg cgaaaaacgt aaagcgctgc ttctcagtca
    14941 gatccagcag caacggctgg atctgtccgc cagccgtcgc gactggctgg agaccaccgg
    15001 cgcgtacgat cgcggctgga atacggtgtt aagcctgcgc tcctgggcgc tggtcggtag
    15061 cagcgtaatg gccatctgga ccatccgtca tcctaatatg ttggtacgct gggcgaaacg
    15121 cggcctgggt atctggagcg cctggcgcct ggtaaaaact accctccgtc aacaacagct
    15181 ccgcggttaa tatcttttct tttatagcat cgcgccatca ggttatcacc cgattacacc
    15241 tggtggcgcg atacttttat gcatatcgtc tctttatcaa tcactcaaat tttttgaaaa
    15301 aatttggcaa ttttccttgc taacaattcc tgtacgccac gtttatgatt ctctccagcg
    15361 ataacaatga cgcgctaaac cgcgccattg ctcatgaaaa tagcagcagc cgccgaatcg
    15421 gcctcctgga gaataaaatg aaaaaattag aagatattgg tgtactgata gcgcgtattt
    15481 taatgccagt tctgtttatt accgcaggat ggggaaaaat tagcggctat gcgggcacac
    15541 agcagtatat ggaagcgatg ggcgtaccag gattcctgct gccgctcacc atactgcttg
    15601 agttcggcgg cggtctggcg attctgctgg ggttcctcac ccgcaccact gcgcttttca
    15661 ccgctggttt tacgttgctg acggcattga tcttccatag caattttgca gaaggtgtaa
    15721 actcgctgat gtttatgaaa aacctgacca ttgccggagg attcttatta ctggcgttaa
    15781 ccgggcctgg cgcgttcagc cttgaccgtc tgctgaataa aaagtggtaa gcaatctata
    15841 ctcaattaaa aaagcgaggg aatagcgcct cgcttttgtt atctgaagga gagagacatg
    15901 ggacaactga tcgatggcgt ctggcacgat acctggtatg acaccaaatc ttccgggggg
    15961 aaatttcagc gttcagcgtc ggctttccgc aactggctta ccgctgacgg cgcgcccgga
    16021 ccttccggcg aaggcggatt cgccgcagaa aaagatcgtt accatctgta cgtttccctt
    16081 gcctgcccct gggcgcatcg cacgctcatt ttccgtaaac tgaaaggtct ggagccgttt
    16141 attccggttt ctgtcgtgaa tccattgatg ctggaaaacg gctggacgtt tgatgatact
    16201 tttccggcgg ccaccggcga taccctctat cagcatgaat ttctctacca gttgtatctg
    16261 cacgccgatc cacactacag cggccgcgtc accgtgccgg tcttatggga taaaaaaaat
    16321 catactatcg tcagcaacga gtccgccgaa atcattcgta tgtttaactc cgctttcgat
    16381 gggctgggcg ctaaagccgg ggattactat ccccccgcgc tgcaaagcaa aattgacgag
    16441 ttaaacggct ggatttatga caacgttaat aacggcgttt ataaagcagg cttcgccact
    16501 agccagcaag cgtatgatga agcggtagaa aaggtgttta ctgcgctggc gcgcctggaa
    16561 cagattctcg gacagcaccg ctatctgacg ggcaaccagt tgaccgaggc ggatatccgc
    16621 ttatggacga ccctggtacg ctttgatccg gtttacgtga ctcatttcaa atgcgacaaa
    16681 taccgaatca gcgactacct gaatctgtac ggtttcctgc gcgatatcta tcaaataccg
    16741 ggcattgctg aaaccgtcaa tatggaccat attcgtcacc actatttccg tagccataaa
    16801 acgattaacc ccacgggtat catttctgtc ggaccgtggc aggatctgct cgaacctcac
    16861 gggcacgacg tgcgctttgg ctaatttcag gcgtcctccg ggacgcctta ttaataaatg
    16921 ccacaaatat ttaccagcat ttcattcgca gctattctta gtttgattac tttaaaaaca
    16981 agtgattgaa ccattattga ggcgaaaatg gattggtatt taaaggtttt aaaaaattat
    17041 ctgggatttg gcggccgcgc gcgacgcaaa gagtactgga tgtttattct ggtcaatatc
    17101 atctttacct ttgtgttggg cctgctggac gccatgcttg gctggcaacg cgccgggggt
    17161 gaaggcgttc tgaccaccat ttacggcgtt ctgatctttt taccgtggtg ggccgtgcag
    17221 ttccgtcgtc tgcatgacac tgaccgctcc gcatggtggc tactgttgct acttatcccc
    17281 attatcggct ggcttatcat catcgcgttc aactgccaga atggtacacc gggcgacaac
    17341 cgcttcggcc ccgatccgaa acgtttttcc tgagggcggc gcggcgccgc ttttaaagcg
    17401 ccgcgcgcta tttattttcc ggcgaatagc ttaggtattt cccgcaggca ccaggctttt
    17461 gcctccccca tactgtcgcg ccgccaggcc ataataatat cgatttcgct ggtcgattcc
    17521 gggctgacta cgcgtagccg cccttcggca atatcctgtt ccaccatcga atatggcatc
    17581 gtcgcgacgc caagcccggc cagcagcgcc tgacgtttat cttcaatcgt gcttaccgtc
    17641 agacgtggct gcttatccag cagttgcacc gttaataccg gccgctcgcg cgcggtatcc
    17701 gctaccgcta cgccgcggta tttaacccgc gtcacttccg aaagcggctc cggctcctga
    17761 tgaatagagt ggtcaggcgc ggcgacatac acattcatta acgtatacaa cttacgggag
    17821 ttaatttccg acgacgatcg aaaatgcata tccggggcga taacgatatc cgcccgtccc
    17881 tgctcaagcc gctcccatgc gccagccagt acttcggtaa tcaatgaaag ctgcgtattg
    17941 gctttagcgg ccagccggtc gatcagcgga aaaaaagcag gcgtcggtac cagagcttca
    18001 gtgaccagcg tcagatgcgt ttcccaaccg cgggccaacg cttcagcatc cgtcgttaac
    18061 ttgtctgccg cttccagcaa tacccgcccg cgttccagca gcatacgtcc gacgttggtg
    18121 aattttgtac gatggccgga gcgatcgaac agtacaacgt ccaactcttc ttccagcttc
    18181 tgcatggtgt aactcagcgc ggagggcacc cgccccaact catcagccgc tgcggcaaaa
    18241 ctgccccggc ggtcaatggc gtccatcaca cgcaatgctt caagcgtcag cgctctctct
    18301 ttagccataa cgttctcatt caggaaattt gaacataccg ggcagaatat ctggctaaca
    18361 atgcagcgtc cagcccctta acataaaagg aagtaaagag aggttaataa cgatgattac
    18421 gacccgaacc gccaaacaat gtggacaggc agactacgga tggctacagg cccgctatac
    18481 cttctccttt ggacactact tcgaccctac actgctgggc tacgcgtcgt tgcgcgtact
    18541 gaaccaggaa gtgctggcgc cgggcgcctc ttttcagcct cgaacttatc caaaggtgga
    18601 tattttaaac ctgattctgg acggcgaagc ggaataccgc gacagcgacg gcaaccatgt
    18661 acaggctaaa gcgggcgaag cgttgctgct cgccgcgcag ccgggcatta gctacagcga
    18721 acataatctc agcaaagtta agccgttaac ccgaatgcaa ctgtggcttg acgcctgtcc
    18781 tgaacgggaa aacgcgctgg tacaaaaaat cccactctcg acggcgcaac aacagcttct
    18841 tgcctcgccc gacggtgagc aaaacagctt acaactgcgc caacaggtct gggtacatca
    18901 tattacgctg gagaaaggcg aatcgcttaa cttccagctt cacgggccgc gcgcctattt
    18961 gcagtcgatt cacggtacgt tccacgcgat gacgcacaac gaagaacgcg aggcgttaac
    19021 ctgcggagat ggcgcattta ttcgtgatga acctaacatt acgctggttg ccgatacgcc
    19081 gctgcgcgca ttactggtag atttaccggt gtagccagcc agaaaaggag tcgcaagatg
    19141 agcaaaaaat cggcgaagaa acgtcagccc gtggtaaaac ctgccgtaca ggaggcgatg
    19201 agcgccgctg tgccgctggg ctatgaagag atgctaaccg aactggaagc catcgtggcg
    19261 gacgccgaag cccggctggc agaagaagag gccgcagcct gaaatcatgc cggatggcgg
    19321 cgcaagcgcc cgatccggct gataacgggt agacccgata agcgcagcgc catcgggcaa
    19381 cacgctgccc cgacgtcatg ccggggcgtt attattaatg cgctttactg gccataatct
    19441 cgatgatctg cttgtctgtc tgctgcattg agcgacacgc cagcgaacac aaattcgaaa
    19501 tagattgttc gacattgtgc gccacaatcc cttcgtttcc ggtcaccgcc gtatcatcca
    19561 acgccatcag tacggctttc cacgccgccg acgcgctggt agagactttc atcgcgcagc
    19621 tattcgacgc gccatcgcaa atcatcccgc tgacatcacc aatcatactg ctgatagcca
    19681 ttgcgatagt gtcgtaacga ccatctatca gccacgccat acccgctgcc gcgcccattg
    19741 ccgccgtagt tgccgcgcac agcgccgaca aacgcggaag ctgatggtga atatagatag
    19801 cgctcaaatg cgataacatt agcgcgcgcg ccaggcactc gtcatcggcg ccgacatgtt
    19861 cagcaaccac catgactggc accgtggcgg taatcccctg gttgccggag ccggagttgc
    19921 tcatcgcggg caacgtggca ccgcccattc tggcgtctga cgccgcgctg gtacggatca
    19981 aaatcgccgt ggagagatct ttcgccagca gaccgcgatc gcactgtttg gccagcgtcg
    20041 aaccaatatg cagcccccag gaaccacgca agccctcctg cgacaacgcg ccgtttagcc
    20101 tggccgcatc gagaataaag cggatagcgt caaagggcac cgcattcaca aacgccagga
    20161 tctcttccag cgaggtatga gacagcactc ccagtggcga ggttttttct tcttcctgcg
    20221 cattatcggc ttgggtaaat accacgccct tgtcggtttc tatccgcaca atatttgtat
    20281 gatcgccgac gatcgtgaca catgcccagc tatcgccgct atacactttc gcccgtgaaa
    20341 acaggatatc gttacatggc tcctgcaaca tcactgcaac atgtccggcg gccagcatcg
    20401 cttttgcatc ggcaacggct ttagcggaag cgtcttttaa cacctccaac ccggctttcg
    20461 catcaccgcc caacgcgcca agcgccgcgg cgatcggtag ccctaccatt cccgttcctg
    20521 gaacggtaac gcccatacca tttttcatca gattaggcga aacccacgcg tcaatgcgtt
    20581 caactgtgcc gtcaagttca gccgccgccg ccgctgctgc cagcgccagt gaaattggct
    20641 cagtacaccc cagcgccggt tttacttctt cctgtacggc caggataaaa ctttgccaca
    20701 atggatttat tttagattca aacataacaa caaccttaat ctcaggtata tcaagagaat
    20761 gccaggaacg gagaaacgca tagcagcaga ccggtaataa taatcaggta caacgaagcg
    20821 cctttatatt tgtgcaatgc gggaaccttg tagaccaacc atgccggaat taaacagccc
    20881 accataccga agatagggct acaaatagag gtgaagctca gtaccggcgc gttgagcaca
    20941 atggcgctcc aggccagcaa aatagcgaaa atcataatgc cgcgctgtac cagattttcc
    21001 ttaatcttct cggcgggcat tttgcggcgc aggatattca tcacaatgcc ttgcgtcgct
    21061 tcgcggaatc ctaaataaac gccaaagaag gcggtcatga cggcaaagat gttcagaatt
    21121 acgctaacca ctttgaccca gctagcgcca tcgccgctaa taaattgcgc ggcgatcgcc
    21181 agggcggaaa tattctgctc gtaggctttc accgcttcgt catgccccat cgccagggtg
    21241 aaggaaaccg catagaaaaa gacggtaacg aacaggatgc caaacgcgat attcatggcg
    21301 cgcagcgctt atggcgtgcg acctcaatag atttttcgcg tgaacggtaa gagatcacca
    21361 ttgggcttaa cgtctggata aataaaatcg aggtcagcgt aaatggcagg gtaataatgg
    21421 cgtttttaat cagcagggcc atcggcggca gcgcgccaat gttatacaga tgccacatac
    21481 ccaccataga gacgcccagc gccgccacta ccagtagctt ggtcagcacc atgccggtgg
    21541 aaattttgaa cagtaatttt tcaccgcgtg aggaaatcgc caccaggatg cagatcagca
    21601 ccagaccata aaatggacta tcggaaagta atccttccgt tacgccgaaa gtatgcagat
    21661 aagaggcgct gtcgttagta atcgccgtag aatagacgaa catccagatg acgagcatca
    21721 caaagtacag cgcgcctaat aaaatacccc agtttttgcc cagatagccg ctgatcacgc
    21781 tggggtagtc tttacattcc ggggattccg ccagcgtatt aataaacagc cgctggaaca
    21841 ggtacatggc cggataacca ataatagaag agagtaaaaa gacccaaagt cccatcaggc
    21901 caacctagac aggaagaaaa acgatccctg cgccgatcgc catcccgata ctcataatga
    21961 cccagccggt gtcggtacta tcaaatttga tggcttcacg ccattcgctt tctgtcatcc
    22021 ctgcccgacg cgccggggct gatgcgtcga ggattacgct ggtattacta gccgattcca
    22081 taaaattctc gctcaatgtg taggtagagg tttttttatt tttcgtgccg cagcaaggcg
    22141 atatgcagaa cgtgaggtgc aggtactttc ttgtaataag aaaatcatac gcgcacgata
    22201 agagaaaaac ttaccaat
//
LOCUS       DAJVBX010000061        22027 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.061, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000061 DAJVBX010000000
VERSION     DAJVBX010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 22027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22027
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.061"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            155..553
                     /locus_tag="OPV72_001971"
                     /pseudo
     CDS             155..553
                     /locus_tag="OPV72_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459103.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
     gene            complement(629..1834)
                     /locus_tag="OPV72_001972"
     CDS             complement(629..1834)
                     /locus_tag="OPV72_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001669153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCR9914277.1"
                     /translation="MLILKAYKFRLEPTPEQSQRLRQLCGCARFVWNLGLAETKRILG
                     SGEKLPSAFELNRMLTVWKKMPGHIFLQDAYTDNLQQKLKDLHTAWKRCFDKKLAAKA
                     PVWKRKNEGRDSIRFVNFEKYCRLENRRVKLPSGLGWVKFRQSQRVNGKIKNATISQL
                     AGQWYISFQVEVETAEPNHTSTTIVGLDAGVTKLATLSDGTVYQPVNSFKASQRKLAT
                     LQRQLSRKVRFSSNWQKQKRKVQHLHSHIANIRRDYLHKVTSEISKNHAMIVIEDLKV
                     SNMSKSAKGTAEQHGRNVKAKSGLNRSILDQGWYEMRRQLEYKQLWRGGQVLAVPPAY
                     TSQRCACCGHTAKENRLSQSKFVCQACGYTANADVNGARNILAAGHAVLACGGMVQSG
                     RPSETGTRR"
     gene            1857..2297
                     /gene="tnpA"
                     /locus_tag="OPV72_001973"
     CDS             1857..2297
                     /gene="tnpA"
                     /locus_tag="OPV72_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISSen6 family
                     transposase"
                     /protein_id="HCR9914278.1"
                     /translation="MFATLLFLRSTSIQKHKINRSRHAAFLLHVHLVFITKYRRKILG
                     ESHYAAFHQYAAEVCRDFGGELKESNGDVDHVHMLIEYPPTVQLSVLVNSLKAVTSRR
                     LRNEFIDLRGAYGKAVLWSRSYFAGSCGGAPLEVVKQYIQHQRG"
     gene            2363..2593
                     /locus_tag="OPV72_001974"
     CDS             2363..2593
                     /locus_tag="OPV72_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914279.1"
                     /translation="MELRWCTALLVSDPLHMLRLKTIAQDNGIDSRSSPTRATRYKSW
                     WAQTRFLLRETFYYSGYRLLRYMPVQNNSITP"
     gene            2637..4988
                     /gene="polB"
                     /locus_tag="OPV72_001975"
     CDS             2637..4988
                     /gene="polB"
                     /locus_tag="OPV72_001975"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase II"
                     /protein_id="HCR9914280.1"
                     /translation="MAQAGFILTRHWRDTPQGTEVSFWLATDNGPLQATLAPQESVAF
                     IPTSQTSRAASLLQAEKDYRLTPLQLRDFHRQPVSGLYCRTHRQLMRMEKLLRENGVT
                     VYEADVRPPERYLMERFITSPVWVDGEMRNGVIRNARLKPHPDYRPPLKWVSLDIETT
                     RHGELYCIGLEGCGQRTVYMLGPANGDERQLDFELVYVASRPQLLEKLNAWFAEHDPD
                     VIIGWNVVQFDLRMLQKYAERYRIPLRLGRDNSELEWREHGFKNGVFFAQARGRVIID
                     GIDALKSAFWNFSSFSLEAVSQELLGEGKSIDNPWDRMDEIDRRFAQDKPALATYNLK
                     DCELVTRIFHKTEIMPFLLERATINGLPVDRHGGSVAAFGHLYFPRMHRAGYIAPNLG
                     EVPPLASPGGYVMDSQPGLYDSVLVLDYKSLYPSIIRTFLIDPVGLVEGMAQPDPEHS
                     TEGFLDAWFSREKHCLPEIVSQIWHGRDEAKRQGNKPLSQALKIIMNAFYGVLGTTAC
                     RFFDPRLASSITMRGHAIMRQTKALIEAQGYDVIYGDTDSTFVWLRRAHSEADAAEIG
                     HRLVRHVNEWWAQTLQQQNLTSALELEFETHFCRFLMPTIRGADTGSKKRYAGLIQEG
                     DSQRMVFKGLETVRTDWTPLAQRFQQELYLRVFRNEPYQDYVRETIDKLMAGELDAQL
                     VYRKRLRRPLHEYQRNVPSHVRAARLADEQNLKQGRPAQYQNRGAIKYVWTVNGPEPV
                     DYQQSPLDYEHYLTRQLQPVAEGILPFVEDNFATLLTGQLGLF"
     gene            5162..8068
                     /gene="rapA"
                     /locus_tag="OPV72_001976"
     CDS             5162..8068
                     /gene="rapA"
                     /locus_tag="OPV72_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001117023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase-associated protein RapA"
                     /protein_id="HCR9914281.1"
                     /translation="MPFTLGQRWISDTESELGLGTVVAMDARTVTLLFPSTGENRLYA
                     RSDSPVTRVMFNPGDTITSHEGWQLHIDEVKEENGLLVYVGTRLDTEETNVTLREVLL
                     DSKLVFSKPQDRLFAGQIDRMDRFALRYRARKFQSEQYRMPYSGLRGQRTNLIPHQLN
                     IAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIIVPETLQHQWLVE
                     MLRRFNLRFALFDDERYTEAQHDAYNPFETEQLVICSLDFARRNKQRLEHLCDAEWDL
                     LVVDEAHHLVWSTDAPSREYMAIEQLAERVPGVLLLTATPEQLGMESHFARLRLLDPN
                     RFHDFEQFVEEQKNYRPVADAVAMLLAGNKLSNDELNRLGDLIGEQDIEPLLQAANSD
                     RDDAQAARDELVSMLMDRHGTSRVLFRNTRNGVKGFPKRELHTVKLPLPTQYQTAIKV
                     SGIMGARKSAEDRARDMLYPEQIYQEFEGDTGTWWNFDPRVEWLMGYLTSHRSQKVLV
                     ICAKATTALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIG
                     SEGRNFQFASNLVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRW
                     YHEGLDAFEHTCPTGRAIYDSAYASLINYLAAPEETDGFDDLIKSCREQHEALKAQLE
                     QGRDRLLEINSNGGEKAQQLAQSIEEQDDDTNLIAFAMNLFDIVGINQDDRGDNLIVL
                     TPSDHMLVPDFPGLPEDGCTITFERDVALSREDAQFITWEHPLIRNGLDLILSGDTGS
                     STISLLKNKALPVGTLLVELVYVVEAQAPKQLQLNRFLPPTPVRMLLDKNGNNLAAQV
                     EFETFNRQLSAVNRHTGSKLVNAVQQDVHAILQLGETQIEQSARALIDNARREADEKL
                     SGELSRLEALRAVNPNIRDDELAAIDSNRQQVLESLNQAGWRLDALRLIVVTHQ"
     gene            8080..8739
                     /gene="rluA"
                     /locus_tag="OPV72_001977"
     CDS             8080..8739
                     /gene="rluA"
                     /locus_tag="OPV72_001977"
                     /EC_number="5.4.99.28"
                     /EC_number="5.4.99.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tRNA pseudouridine(32) synthase/23S
                     rRNA pseudouridine(746) synthase RluA"
                     /protein_id="HCR9914282.1"
                     /translation="MGMENYNPPQEPWLVILYQDEHIMVVNKPSGLLSVPGRLEAHKD
                     SIMTRIQRDYPQAESVHRLDMATSGVIVVALTKAAERELKRQFREREPKKQYVARVWG
                     HPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYNVVEFAADNTARVVLKPITGR
                     SHQLRVHMLALGHPILGDQFYASPEALSLAPRLQLHAEMLTITHPAYGNSMTFKVPAD
                     F"
     gene            complement(8834..9646)
                     /gene="djlA"
                     /locus_tag="OPV72_001978"
     CDS             complement(8834..9646)
                     /gene="djlA"
                     /locus_tag="OPV72_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone DjlA"
                     /protein_id="HCR9914283.1"
                     /translation="MQYWGKIIGVAVALMMGGGFWGVVLGLLVGHMFDKARSRKMAWF
                     ANQRERQALFFATTFEVMGHLTKSKGRVTEADIHIASQLMDRMNLHGDSRTAAQNAFR
                     VGKADNYPLREKMRQFRSVCFGRFDLIRMFLEIQIQAAFADGSLHPNEREVLYVIAEE
                     LGISRVQFDQFLRMMQGGAQFGGGYHQQSGGGWQQAQRGPTLEDACNVLGVKTTDDAT
                     TIKRAYRKLMSEHHPDKLVAKGLPPEMMEMAKQKAQEIQKAYELIKEQKGFK"
     gene            9900..12254
                     /gene="lptD"
                     /locus_tag="OPV72_001979"
     CDS             9900..12254
                     /gene="lptD"
                     /locus_tag="OPV72_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS assembly protein LptD"
                     /protein_id="HCR9914284.1"
                     /translation="MKKRIPTLLATMIASALYSHQGLAADLASQCMLGVPSYDRPLVK
                     GDTNDLPVTINADNAKGNYPDDAVFTGNVDIMQGNSRLQADEVQLHQKQAEGQPEPVR
                     TVDALGNVHYDDNQVILKGPKGWANLNTKDTNVWEGDYQMVGRQGRGKADLMKQRGEN
                     RYTILENGSFTSCLPGSDTWSVVGSEVIHDREEQVAEIWNARFKVGPVPIFYSPYLQL
                     PVGDKRRSGFLIPNAKYTTKNYFEFYLPYYWNIAPNMDATITPHYMHRRGNIMWENEF
                     RYLTQAGAGLMELDYLPSDKVYEDEHPKEGDKHRWLFYWQHSGVMDQVWRFNVDYTKV
                     SDSSYFNDFDSKYGSSTDGYATQKFSVGYAVQNFDATVSTKQFQVFNDQNTSSYSAEP
                     QLDVNYYHNDLGPFDTRIYGQAVHFVNTKDNMPEATRVHLEPTISLPLSNRWGSLNTE
                     AKLMATHYQQTNLDWYNANNSKKLEDSVNRVMPQFKVDGKLVFERDMAMLAPGYTQTL
                     EPRVQYLYVPYRDQSGIYNYDSSLLQSDYNGLFRDRTYGGLDRIASANQVTTGVTTRI
                     YDDAAVERFNVSVGQIYYFTESRTGDDNIKWENDDKTGSLVWAGDTYWRISERWGLRS
                     GVQYDTRLDSVATSSSSLEYRRDQDRLVQLNYRYASPEYIQATLPSYYSTAEQYKNGI
                     NQVGAVASWPIADRWSIVGAYYFDTNSSKPADQMLGLQYNSCCYAIRVGYERKLNGWD
                     NDKQHAIYDNAIGFNIELRGLSSNYGLGTQEMLRSNILPYQSSM"
     gene            12308..13594
                     /gene="surA"
                     /locus_tag="OPV72_001980"
     CDS             12308..13594
                     /gene="surA"
                     /locus_tag="OPV72_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase SurA"
                     /protein_id="HCR9914285.1"
                     /translation="MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDG
                     LMQSVKLNAGQAGQQLPDDATLRHQILERLIMDQIILQMGQKMGVKITDEQLDQAIAN
                     IAKQNNMTMDQMRSRLAYDGLNYSTYRNQIRKEMIISEVRNNEVRRRITVLPQEVDAL
                     AKQIGTQNDASTELNLSHILIALPENPTSEQVNDAQRQAESIVEEARNGADFGKLAIT
                     YSADQQALKGGQMGWGRIQELPGIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGQ
                     SQSISVTEVHARHILLKPSPIMNDQQARLKLEEIAADIKSGKTTFAAAAKEYSQDPGS
                     ANQGGDLGWATPDIFDPAFRDALTKLHKGQISAPVHSSFGWHLIELLDTRKVDKTDAA
                     QKDRAYRMLMNRKFSEEAATWMQEQRASAYVKILSN"
     gene            13594..14583
                     /gene="pdxA"
                     /locus_tag="OPV72_001981"
     CDS             13594..14583
                     /gene="pdxA"
                     /locus_tag="OPV72_001981"
                     /EC_number="1.1.1.262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxythreonine-4-phosphate dehydrogenase
                     PdxA"
                     /protein_id="HCR9914286.1"
                     /translation="MSSAQRVVITPGEPAGIGPDLVVQLAQRAWPIELVVCADGALLT
                     ERAAMLGLPLSLLPYSPDVPAAPQPAGTLTLLPVSLRAPAIPGQLTVENGPYVVETLA
                     RACDGCLNGEFAALITGPVHKGVINDAGIPFTGHTEFFEERSQAKKVVMMLATEELRV
                     ALATTHLPLRAIADAITPALLHEVIAILHHDLRTKFGIAEPRILVCGLNPHAGEGGHM
                     GTEEIDTIIPVLDELRAQGMKLNGPLPADTLFQPKYLDNADAVLAMYHDQGLPVLKYQ
                     GFGRGVNITLGLPFIRTSVDHGTALELAGRGKADVGSFITALNLAIKMIVNTQ"
     gene            14580..15401
                     /gene="rsmA"
                     /locus_tag="OPV72_001982"
     CDS             14580..15401
                     /gene="rsmA"
                     /locus_tag="OPV72_001982"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HCR9914287.1"
                     /translation="MNNRVHQGHLARKRFGQNFLNDRFVIDSIVSAINPQKGQAMVEI
                     GPGLAALTEPVGERLDKLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTMNFGELSA
                     QLGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRL
                     SVMAQYYCQVIPVLEVPPSAFTPPPKVDSAVVRLVPHATMPYPVKDIRVLSRITTEAF
                     NQRRKTIRNSLGNLFSVETLTEMGIDPAMRAENISVAQYCQMANYLSENAPLKES"
     gene            15404..15781
                     /gene="apaG"
                     /locus_tag="OPV72_001983"
     CDS             15404..15781
                     /gene="apaG"
                     /locus_tag="OPV72_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Co2+/Mg2+ efflux protein ApaG"
                     /protein_id="HCR9914288.1"
                     /translation="MINSPRVCIQVQSVYIEAQSSPDDERYVFAYTVTIRNLGRAPVQ
                     LLGRYWLITNGHGRETEVQGKGVVGVQPRIAPGEEYQYTGGAVIETPLGTMQGHYEMI
                     DENGDAFTIDIPVFRLAVPTLIH"
     gene            15792..16640
                     /gene="apaH"
                     /locus_tag="OPV72_001984"
     CDS             15792..16640
                     /gene="apaH"
                     /locus_tag="OPV72_001984"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     ApaH"
                     /protein_id="HCR9914289.1"
                     /translation="MATYLIGDVHGCYDELIALLQQVEFTPDTDTLWLTGDLVARGPG
                     SLDVLRYVKSLGNSVRLVLGNHDLHLLAVFAGISRNKPKDRLTPLLEAPDADELLNWL
                     RRQPLLQVDEEKKLVMAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMP
                     NNWSPELSGLARLRFITNAFTRMRYCFPNGQLDMYSKASPENAPAPLKPWFAIPGPVS
                     EAYSIAFGHWASLEGKGTPEGIYALDTGCCWGGELTCLRWEDKQYFVQPSNRQMDMGE
                     GEAVNA"
     gene            complement(16736..17215)
                     /gene="folA"
                     /locus_tag="OPV72_001985"
     CDS             complement(16736..17215)
                     /gene="folA"
                     /locus_tag="OPV72_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020456510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 3 dihydrofolate reductase"
                     /protein_id="HCR9914290.1"
                     /translation="MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVVMGR
                     HTWESIGRPLPGRKNIIISSQPGTDDRVQWVKSVDEAIAACGDAPEIMVIGGGRVYEQ
                     FLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR"
     gene            complement(17414..19276)
                     /gene="kefC"
                     /locus_tag="OPV72_001986"
     CDS             complement(17414..19276)
                     /gene="kefC"
                     /locus_tag="OPV72_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     protein KefC"
                     /protein_id="HCR9914291.1"
                     /translation="MDSHTLLQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGPW
                     GLRLVTDAESILHFAEIGVVLMLFVIGLELDPQRLWKLRASVFGGGALQMVVCGGLIG
                     LFCMFLGLRWQVAELIGMTLALSSTAIAMQAMNERNLTVSQVGRSAFAVLLFQDIAAI
                     PLVAMIPLLAASGASTTLGAFALSALKVAGALALVVLLGRYVTRPALRFVARSGLREV
                     FSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLF
                     FIGVGMSIDFGTLVENPLRILLLLAGFLAIKIVMLWLVARTLGVPAKQRRWFAVLLGQ
                     GSEFAFVVFGAAQMADVLEPEWAKALTLAVALSMAATPIFLVLLTRMEKTATGEAREA
                     DEIDEEQPRVIVAGFGRFGQIAGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDA
                     TRMDLLESAGAAKAEVLINAIDDPQTNLQLSELVKTHFPHLQIIARARDVDHYIRLRQ
                     AGVAMPERETFEGALKSGRQALEALGLGRYEARERADLFCHFNTRMVEEMAKGENDPL
                     SRAAAYKRTSAMLSEIITEDREHLSLIQRHGWQGTAEGKHSGKAADEPEVKPSI"
     gene            complement(19269..19799)
                     /gene="kefF"
                     /locus_tag="OPV72_001987"
     CDS             complement(19269..19799)
                     /gene="kefF"
                     /locus_tag="OPV72_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     oxidoreductase KefF"
                     /protein_id="HCR9914292.1"
                     /translation="MILIIYAHPYPHHSHANKQMLEQAGTLENVEIRSLYHLYPDFNI
                     DVAAEQEALSRASLIVWQHPMQWYSVPPLLKLWMDKVLTHGWAYGHGGTALHGKHLLW
                     AVTTGGGENHFAIGSHPGFAVLSQPLQATALYCGLKWLPPFAMHCTFICDDDTLQAQA
                     RQYKQRLLAWQEVNHG"
     gene            complement(20206..22004)
                     /locus_tag="OPV72_001988"
                     /pseudo
     CDS             complement(20206..22004)
                     /locus_tag="OPV72_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000948383.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
BASE COUNT         5234 a         6074 c         5705 g         5014 t
ORIGIN      
        1 atgattcaaa attagcagtt ataggataat tatatctgct gtatataccg gcatcattat
       61 attgataaat atacgtcagc aaaaatatct gacgctaaaa gccattttat cgttaaaata
      121 ttcattacac ccgtcacggg gaacgaactc attcatgaaa tatcgctaca tcctcagaat
      181 cgcggcaggc atcattctca ttatggccat ggtgtttatc cataacgcta tcgctattta
      241 tcagttcagt cagcaaaacc agacgcgcgt agctgactgc gcgattgtcg caggagcagg
      301 cgttagcgga aaaacgcctt ctcccgtttt tcaggccaga ctggatcatg ccatctggct
      361 ttaccaacaa cacattgtcc gcgcgttggt attaaccggc ggctacggcg ctggcgcaac
      421 ggtttccgac gcggcgatag cccgtcaata cgttctggaa aaaggcattc cggctaaggc
      481 gatttttatt gaagagcgct ctaccgtgac gcgcgaaaat attcgttacg caaaacagat
      541 actgcgacaa caacattgac atcctccccc accttcgcac ttcgtgactc aggtggggaa
      601 ttcccattag tgggtgacga ctgattgctc agcgtctggt tcctgtttca gacgggcggc
      661 ctgactgcac catccctcca caggcaagaa cggcgtgccc cgccgctaaa atgttacgag
      721 cgccgtttac atcagcgttc gctgtatatc cgcatgcctg acacacaaat ttactttgtg
      781 acaggcgatt ttctttcgcg gtatgaccac agcacgcgca acgctggctt gtgtatgctg
      841 gcggaaccgc aagcacctga ccgccacgcc agagctgttt gtactcaagc tggcggcgca
      901 tttcatacca gccctgatcc agtatcgaac ggttcagacc tgatttggcc ttgacgtttc
      961 gtccgtgctg ttctgctgta ccttttgccg atttcgacat gttactaacc ttcaaatcct
     1021 caatgactat catcgcgtgg tttttgctga tttcactggt aactttatga aggtagtcgc
     1081 gccggatatt ggctatgtgc gagtgcagat gctggacttt tcgcttttgt ttctgccagt
     1141 tactgctgaa tctgacttta cggcttaact gccgctggag tgttgccagc ttgcgctgac
     1201 ttgctttaaa actgttgact ggttggtata ccgtaccgtc tgaaagcgtg gcgagttttg
     1261 ttactcctgc gtccagaccg actatcgttg tgcttgtgtg attgggttct gccgtttcaa
     1321 cttcaacctg aaacgagata taccactgtc ccgctaactg actgattgtc gcatttttga
     1381 ttttaccgtt cacacgttga gattgccgga attttaccca cccaagacct gacggtagct
     1441 tcactctgcg attttcaagg cggcaatatt tctcaaagtt cacaaaacgg attgagtctc
     1501 tgccctcatt ttttcgtttc cataccgggg ccttagctgc gagcttttta tcaaagcaac
     1561 gtttccatgc agtatgcagg tctttcaact tttgttgcag attgtcggta taagcatcct
     1621 gtaaaaagat gtgtcccggc atttttttcc acactgtaag catcctgttc aactcgaaag
     1681 ccgaaggtaa cttttcgcct gaaccaagga tgcgctttgt ctccgcaaga cctaaattcc
     1741 agacaaaacg ggcgcaacca cataactgcc gcaaacgctg cgactgttca ggcgttggtt
     1801 ccagtctgaa tttgtaggct ttcaggatta gcatcatcac tcagtgtgta ggagatttgt
     1861 ttgctacgtt actgttttta cggtcaactt caatacaaaa acataaaatt aatcgttcaa
     1921 gacatgccgc cttccttttg catgttcatc ttgtctttat aacaaaatac cgtcgaaaga
     1981 tactgggtga gtcacactat gctgcattcc atcagtatgc agcagaagtc tgccgtgatt
     2041 ttggcggaga acttaaagaa agtaacggag acgtcgatca tgtccacatg ctgatcgaat
     2101 acccaccaac agtgcagctt tcggtactgg ttaactcact gaaagctgtg acatcccgcc
     2161 gtctgcgaaa cgaatttatt gatttgcggg gagcatacgg aaaagccgtg ctctggtcga
     2221 ggtcatactt tgctggctcg tgcggaggtg cgccgctgga agttgtgaag caatacattc
     2281 aacatcagcg tggctgatga tccttcgggc ttttcaagcc cgtccaaatt cccctcccgc
     2341 cttatgtcgg cgggagtacc ctttggagtt aagatggtgc acagcgttac tggtcagcga
     2401 tccgctgcat atgctgcgtc tgaaaactat cgctcaggat aatggtatcg atagccgctc
     2461 atcacccacg cgagccaccc gctataaatc ctggtgggcg caaacccgct tcttactgcg
     2521 agaaactttt tattacagcg gatatcggct tttacgttat atgcctgtac aaaataacag
     2581 tattaccccc taaaacaggt tataattagc gtgaattttt tagacaggta atcatcgtgg
     2641 cgcaggcagg tttcatttta acccggcact ggcgggatac gccgcaaggg acggaggtct
     2701 ctttctggct ggcgacagac aacggccctt tgcaggcgac gctggcgccg caagagtccg
     2761 tggcgtttat tccgaccagc cagacctccc gcgccgcctc gctgctacag gcggaaaaag
     2821 actatcgcct gacgccgctc cagctgcgag actttcaccg tcagccggta tccggtctgt
     2881 attgccgcac tcaccgccag cttatgcgga tggagaaact gctgcgcgaa aacggcgtca
     2941 ccgtttatga agcggatgtc cgcccgccgg agcgttacct gatggaacgt tttatcactt
     3001 cgcctgtttg ggtagatggc gagatgcgca acggcgttat ccgcaatgcg cgtcttaaac
     3061 cccaccccga ctatcgaccg ccgctaaaat gggtctcgct ggatatcgaa accacgcgac
     3121 acggcgagct gtattgcatt ggtctggaag gctgcggcca gcgtaccgtt tatatgctgg
     3181 gcccggcgaa cggcgatgag cgccaactgg acttcgagct tgtgtatgtc gccagccgcc
     3241 cgcagttgct ggaaaaactc aacgcctggt ttgccgaaca tgatcctgac gtcatcatcg
     3301 gctggaacgt ggtgcagttc gacctgcgta tgctgcaaaa atatgccgaa cgctaccgta
     3361 tccctttacg gctggggcga gacaatagcg aactggagtg gcgcgaacat ggcttcaaaa
     3421 acggcgtttt tttcgcccag gccagagggc gagtcattat cgatggtatc gacgcgctta
     3481 aatccgcgtt ctggaatttt tcgtcttttt cgctggaagc cgtctcgcag gaactgctcg
     3541 gcgaaggaaa atccattgat aacccctggg atcgtatgga tgagatcgat cgccgctttg
     3601 cccaggataa acccgccctc gccacctaca acctgaaaga ctgcgagctg gtcacgcgca
     3661 ttttccataa aaccgaaatc atgccgtttt tgttggaacg cgcgacgatc aacggcctgc
     3721 cggtcgatcg ccacggcggt tcggtcgccg cattcgggca tctttacttt ccgcgaatgc
     3781 accgcgccgg ctatatcgcg cccaatctcg gcgaagtgcc gccgctggca agtcccggcg
     3841 gctacgtaat ggattcacaa cccggattat acgattcagt actggtgctg gattataaaa
     3901 gcctgtaccc gtcaattatc cgcacgtttt tgattgatcc cgtcgggctg gtcgaaggca
     3961 tggcgcagcc ggacccggaa cacagtaccg aaggtttcct tgacgcctgg ttttcacgag
     4021 aaaagcactg cctgccggaa attgttagcc aaatctggca cgggcgcgat gaagccaaac
     4081 gtcagggcaa taaaccgctc tcgcaggcgc ttaaaatcat tatgaacgcc ttttatggcg
     4141 tactcggcac cacggcctgt cgctttttcg atccccgtct ggcgtcgtca atcaccatgc
     4201 gcggtcatgc gattatgcgc cagaccaaag cgctgattga ggcgcagggt tatgacgtga
     4261 tttatggcga taccgattcc actttcgtct ggctccggcg cgcgcattca gaagccgatg
     4321 cggcggaaat cgggcacagg ctggtgcgtc acgtgaacga atggtgggcg cagacgttac
     4381 aacagcaaaa tttgaccagc gcgctggaac tggagtttga aactcacttt tgccgttttc
     4441 tgatgccgac catccgcggc gcggatactg gcagtaaaaa acgctacgcg ggcctgattc
     4501 aggaaggcga cagccagcgc atggtattta aaggtctgga aacggtgcgg accgactgga
     4561 cgccgctggc gcagcgcttt caacaggagc tgtatctgcg cgtttttcgc aatgaacctt
     4621 atcaagacta tgtgcgcgag actatcgata aactgatggc gggcgaactg gacgcgcagc
     4681 tggtttatcg taagcgtctg cgtcgccctt tacatgagta ccagcgtaac gttccgtcgc
     4741 acgttcgcgc cgcccggctg gcggatgaac aaaacctgaa gcagggtcgt ccggcgcagt
     4801 atcagaatcg cggcgccata aaatatgtct ggactgttaa cggccccgag cccgtggatt
     4861 accagcagtc gccgctggat tacgaacact atcttacccg ccagctacaa cccgtggcgg
     4921 aaggaattct tcccttcgtt gaagataatt ttgctacact actgaccggg caactggggt
     4981 tattttgacg cgtgacgaaa gcgccgcctt ccagtaccat agcgcccttt ccattcctgg
     5041 acctaattaa cgccactacc acattagcct ggtagcgggg tcgtatactc gcaattatcc
     5101 agtgctgtcg cctgggaatg gcgagtaatg cctgcaatta aagatataga gccgaacaca
     5161 tatgcctttt acacttggtc aacgctggat cagcgataca gaaagcgagc tgggacttgg
     5221 aaccgttgtt gcgatggatg cgcgaaccgt caccttactt ttcccgtcca cgggggaaaa
     5281 ccgcctgtat gcgcgcagtg attctcccgt gacccgcgtc atgttcaacc ctggcgatac
     5341 gattacaagc catgaaggct ggcagctaca tatcgatgaa gtaaaagaag aaaatggcct
     5401 gcttgtttat gtcggcaccc gcctggatac cgaagaaacc aatgtgacgt tgcgcgaagt
     5461 tctgctcgac agcaagttgg ttttcagtaa gccccaggat cgtctgttcg ccggtcaaat
     5521 cgatcgaatg gatcggttcg cgctgcgcta tcgcgcccgt aaatttcaga gcgagcagta
     5581 ccggatgcca tacagcggcc tgcgcggtca gcggaccaac ctgatcccgc atcagcttaa
     5641 tatcgctcat gatgtgggtc gtcgccacgc gccgcgcgta ctgctggcgg atgaagtggg
     5701 cttaggtaaa accattgaag ccgggatgat tctgcatcaa cagttattat ccggcgcggc
     5761 ggaacgcgta ttgatcatcg ttccggaaac cctgcaacac cagtggctgg tagaaatgct
     5821 gcgccgtttc aacctgcgct tcgcgctgtt cgatgacgaa cgctataccg aagcgcagca
     5881 cgacgcgtat aacccgtttg aaaccgaaca actggtgatc tgctcgctgg atttcgcccg
     5941 ccgcaataag cagcgtctgg aacatttgtg cgacgccgag tgggatttgc tggtggtcga
     6001 cgaagcgcat catctggtgt ggagcaccga tgcgccgagc cgtgaatata tggccatcga
     6061 acagttagct gaacgcgtgc cgggcgtgct gctgctgacc gccacgccag aacagctggg
     6121 gatggaaagc catttcgccc gtctgcgcct gctcgatccg aaccgtttcc acgatttcga
     6181 acagtttgtc gaagaacaga aaaactaccg ccctgtcgcc gatgcggtgg ccatgctgct
     6241 ggcgggcaat aaactcagca acgacgaact gaacagactg ggcgatctga tcggcgaaca
     6301 ggatattgaa ccgctgttac aggccgctaa tagcgatcgc gacgacgcgc aggccgcccg
     6361 tgatgagctg gtgtcgatgc tgatggatcg ccacggtacc agccgcgttc tgttccgcaa
     6421 cacccgtaac ggcgtcaagg ggttcccgaa acgtgaactg catacggtaa aactgccgct
     6481 gccgacccag tatcagaccg ccattaaggt ctccggcatt atgggcgcgc gtaaaagcgc
     6541 ggaagatcgc gcccgcgata tgctctatcc ggaacaaatt tatcaggagt tcgaaggcga
     6601 taccggcacc tggtggaact tcgacccacg cgttgagtgg ctgatgggct atctgaccag
     6661 ccatcgttcg caaaaagtgc tggtgatctg cgccaaggcg accaccgcgt tacagctgga
     6721 gcaggtgctg cgcgaacgcg aaggcatccg cgccgccgtg ttccatgagg gcatgtcgat
     6781 tatcgaacgc gaccgcgccg ccgcctggtt cgccgaagaa gataccggcg cgcaggtgct
     6841 gttatgttcc gaaatcggct ccgaaggacg taacttccag tttgccagca atctggtgat
     6901 gttcgacttg ccgtttaacc cggatctgct ggaacagcgt attggtcgtc tggatcgtat
     6961 cggccaggcg catgatatcc agatccacgt cccgtacctg gaaaaaaccg cccagtcggt
     7021 gctggttcgc tggtatcacg aagggctgga cgcctttgag cacacttgcc cgaccggtcg
     7081 cgcgatttat gattcagcct acgccagtct gattaactat ctggccgcgc ctgaagaaac
     7141 cgacgggttt gacgatctga tcaaatcctg ccgcgaacaa catgaagcgc taaaagccca
     7201 gttagaacag ggccgcgacc gcctgctgga gatcaactcc aacggtggtg aaaaagccca
     7261 acagcttgca caaagcattg aagaacagga cgacgacacc aacctgatcg cgttcgccat
     7321 gaacctgttc gatatcgtcg gcattaacca ggatgatcgc ggcgacaacc tgatcgtgct
     7381 gacgccgtcc gaccacatgt tggtgccgga tttccccggc ctgccggaag acggttgtac
     7441 tatcacgttt gaacgtgacg tagccctgtc tcgcgaagat gcgcagttta ttacctggga
     7501 acatccgctc atccgtaacg gactggatct gatcctctcc ggcgataccg gcagcagcac
     7561 catttcgctg ttgaaaaata aagcgctgcc cgtcggcacg ctgctggtcg aactggttta
     7621 cgtcgtggaa gcgcaggcgc cgaaacagct acaactgaac cgcttcctgc cgccgacgcc
     7681 ggtacgtatg ctgttagata aaaacggcaa caatctggcc gcccaggtcg agtttgaaac
     7741 cttcaaccgc cagctcagcg ccgtgaatcg ccacaccggt agcaaactgg tgaacgccgt
     7801 tcaacaggac gtccacgcca ttttgcaact gggcgagacg cagattgaac agtccgccag
     7861 agcgctgatt gataacgcgc gccgcgaggc agatgaaaaa ctgtccgggg aactgtcgcg
     7921 tctggaagcg ctgcgcgccg tcaacccgaa catccgcgac gacgaacttg ccgctatcga
     7981 cagcaaccgt cagcaggtgc tggaaagcct gaatcaggca ggctggcgtc tggacgcgct
     8041 gcgtcttatc gtcgtcacgc accaataacg gagccgtaca tggggatgga aaactacaat
     8101 ccgccgcagg aaccctggct ggttatcctg tatcaggatg agcacattat ggtggtcaat
     8161 aagcccagcg gcctgttgtc cgtgccgggg cgtctggaag cgcacaaaga cagcattatg
     8221 acgcgtatcc agcgcgacta cccgcaggca gagtcggtgc atcgtctgga tatggccacc
     8281 agcggcgtga ttgtagtggc gctgaccaaa gccgcggagc gggagctaaa acgccagttc
     8341 cgcgaacgtg agccgaaaaa gcagtatgtg gcgcgcgtat gggggcatcc ctccccggcg
     8401 gaaggactgg tcgacttacc gctcatctgc gactggccga accggccaaa gcagaaagtg
     8461 tgttatgaaa ccggcaaacc ggcgcaaacg gaatataacg tggtggaatt tgcggcggat
     8521 aataccgccc gcgtggtgct caaaccgatc accgggcgtt cgcatcagct gcgtgtgcat
     8581 atgctggcgt taggccaccc gatcttaggc gatcagtttt acgcctcgcc ggaagcgttg
     8641 tcgctggcgc cgcgtttgca gttacacgcc gaaatgctga ccattaccca tcccgcttac
     8701 ggtaacagca tgacgtttaa agtcccggca gatttttaaa ttctgagcca atttatgccg
     8761 gagcgcttcg cttgcccggc ctacattcat taacgtaggc cggataaggc gctagccgca
     8821 tccggcaatt caatcacttg aagcctttct gttctttgat tagctcatac gctttctgaa
     8881 tttcctgcgc tttttgcttc gccatctcca tcatttccgg cggcaaccct ttggccacca
     8941 gcttatcggg atgatgctcg ctcatcagtt tgcgataagc gcgtttaatg gtggttgcat
     9001 catcggtggt tttaaccccc agcacattac aggcatcttc cagcgtcggg ccgcgctgcg
     9061 cctgctgcca gccgccgccg gactgttgat gataaccgcc gccaaactgc gcgccgccct
     9121 gcatcatgcg cagaaactga tcgaactgta cgcgggaaat acctaactct tccgcaatca
     9181 catacagcac ttcccgctca ttagggtgca gtgaaccatc ggcaaacgcc gcctggatct
     9241 gaatttccag aaacatccgg atcagatcaa aacgcccgaa gcagacgcta cgaaactgcc
     9301 gcatcttttc acgtaatggg taattatccg cttttccgac ccgaaaggcg ttctgcgcgg
     9361 cagtacgtga atcgccgtgt aaattcatac gatccatcaa ctgactggcg atatgaatat
     9421 ccgcttccgt cacccgtcct tttgatttgg ttaagtggcc catcacctca aaggtggtgg
     9481 caaaaaacag cgcctgccgt tcccgctggt tggcaaacca cgccattttt cggctgcggg
     9541 ctttgtcgaa catatggccc accagcagac ccaggaccac gccccaaaag ccgccgccca
     9601 tcatcagggc tacggcgacg ccaattatct ttccccagta ctgcatagac tccccaaaac
     9661 gttacgctat cggtgaggct atctcccaca aaataaggtg cttttccgcg aatgaaggct
     9721 acggtcattt gtgggacatc gcctataatt tgcattatca tacctgtcat tcaatgccgt
     9781 gcctaacacc acagacgcta aacggcagga ttaacactgg cgcagcgaag atgagtaagt
     9841 taggctgtga ccgtttgtca cgcgcaacgc taccgatgat ggaacaataa atacaacgta
     9901 tgaaaaaacg tattcccact cttctggcca ccatgatcgc cagcgccctt tatagtcatc
     9961 aggggctggc agccgatctc gcctcacagt gtatgttggg cgtgccgagc tacgatcgtc
    10021 ctctggtaaa aggcgatacc aacgatctgc cggttactat caatgccgat aacgctaaag
    10081 gtaactaccc ggacgatgcc gtttttaccg gcaacgtgga cattatgcag gggaatagcc
    10141 gcctgcaagc ggatgaagtg cagcttcatc agaagcaggc ggaaggtcag ccggaacctg
    10201 tacgcaccgt cgatgcgctg ggtaatgtgc attatgatga caatcaggtc atccttaaag
    10261 ggccgaaggg ctgggcgaac ctgaacacca aagacacgaa cgtctgggaa ggcgattacc
    10321 aaatggtggg ccgtcagggg cgcggtaaag ccgatctcat gaagcagcgt ggcgaaaacc
    10381 gctataccat tctggaaaac ggcagcttta cctcctgtct gcctggctcc gatacctgga
    10441 gcgtggtggg gagtgaagtc atccatgacc gtgaagaaca ggttgcggag atctggaacg
    10501 cccggtttaa agtaggtccg gttccgatct tttatagccc ctatttacag ctacccgtcg
    10561 gtgacaaacg tcgctcaggt ttcctgatcc cgaacgcgaa atacacgacc aagaactatt
    10621 tcgagttcta cttaccgtat tactggaaca tcgcgcccaa tatggacgcc accatcaccc
    10681 cgcactatat gcaccgccgc ggcaatatta tgtgggagaa cgaattccgt tatctcacgc
    10741 aggccggcgc cgggttgatg gaattagatt atctgccttc tgataaagtc tacgaggacg
    10801 aacatcccaa agagggcgat aagcaccgct ggttattcta ctggcagcac tcaggcgtga
    10861 tggatcaggt gtggcgtttt aacgtcgatt acaccaaagt cagcgactcc agctacttta
    10921 atgatttcga cagtaagtac ggttccagta ccgacggcta cgcaacgcag aaattcagcg
    10981 tcggctacgc cgtacaaaac tttgacgcta cggtgtcgac caaacaattc caggtcttta
    11041 acgatcagaa caccagcagc tattcagcgg agccgcagtt agacgttaac tactaccata
    11101 acgatctcgg cccgtttgat acccggattt acggtcaggc ggtgcacttt gtcaacacca
    11161 aagacaatat gccggaagcg acccgcgtcc acctggagcc gaccattagt ctgccgctct
    11221 ccaaccgctg gggcagtctg aacaccgaag cgaagctgat ggcgacgcac tatcagcaga
    11281 cgaatctgga ctggtacaac gccaataaca gcaaaaaact ggaagattcg gttaaccgcg
    11341 tcatgccgca gtttaaagtc gacggtaagc tcgtcttcga acgcgatatg gcgatgctgg
    11401 cgccggggta tacccaaacg ctggaaccac gcgtgcagta cctgtatgtg ccgtaccgcg
    11461 accagagcgg catctataac tacgattctt ctttgctgca atccgactat aacggcctgt
    11521 tccgcgaccg cacttatggc ggtctcgacc gtattgcttc cgccaaccag gtcacgaccg
    11581 gcgtcacaac acgcatttat gatgatgccg ccgttgaacg ttttaacgtt tctgttggtc
    11641 aaatctacta tttcacggag tctcgcaccg gcgatgacaa cattaaatgg gagaatgacg
    11701 acaaaaccgg ttcgctggtt tgggcaggtg acacttactg gcgtatttca gaacgctggg
    11761 ggctgcgtag cggagtgcag tacgataccc gtctggatag cgtcgctacc agcagcagca
    11821 gcctcgaata ccgtcgggat caggatcgtc tggtacagtt gaactaccgc tatgccagcc
    11881 cggaatatat tcaggctacg ttgccttcgt attattccac ggcagagcag tataaaaacg
    11941 gcatcaacca ggtgggcgcg gtggcaagtt ggccgattgc cgatcgctgg tcgattgtcg
    12001 gcgcgtacta cttcgatacc aattcgagca aacctgcaga ccagatgctc ggcttgcagt
    12061 acaactcttg ctgctatgcg atccgcgtcg gatacgaacg taagctgaac ggttgggata
    12121 acgataaaca acacgcgatt tatgataacg cgattggctt caacattgag ctgcgcggtt
    12181 tgagctctaa ctacggcctc ggcacgcaag aaatgttgcg ttcgaacatt ctgccgtacc
    12241 aaagctctat gtaatctgat tgatttacaa cgtaatccgc attgcggtta attgaaatgg
    12301 aaaaagtatg aagaactgga aaacgctgct tctcggtatc gccatgatcg cgaataccag
    12361 tttcgctgcc ccccaggtag tcgataaagt cgcagccgtc gtcaataatg gcgtcgtgct
    12421 ggaaagcgac gttgatggct taatgcaatc agtcaaactc aacgcgggtc aggcaggtca
    12481 gcagcttccg gacgacgcca cgctgcgcca ccagatcctg gaacgtttga ttatggatca
    12541 aattatcctg cagatgggtc agaagatggg ggtgaagatc acggatgagc agttggatca
    12601 ggccatcgcc aacatcgcca aacaaaacaa tatgacgatg gatcagatgc gcagccgtct
    12661 ggcttacgat gggctgaact attcaaccta ccgtaaccag attcgtaaag agatgattat
    12721 ctctgaagtg cgcaacaacg aagttcgtcg ccgtatcacc gttttgccgc aagaagttga
    12781 cgcgctggca aaacagattg gcacccaaaa cgacgccagc accgagctga acctgagcca
    12841 tatcctgatt gctctgccgg aaaacccaac ctccgagcag gttaacgacg cgcagcgcca
    12901 ggcggaaagc attgttgaag aagcgcgtaa cggcgcagat ttcggcaaac tggcgattac
    12961 ctactctgcc gaccagcagg cgttaaaagg tggtcagatg ggctggggcc gtattcagga
    13021 gctgccgggg attttcgccc aggcgctgag caccgcgaag aaaggcgaca ttgtcggccc
    13081 gattcgctcc ggcgtcggct tccacattct gaaagtaaac gacctgcgcg gtcagagcca
    13141 gagtatctcc gtgaccgaag ttcacgctcg tcacattctg cttaagccgt cgccgatcat
    13201 gaacgatcag caggcgcgcc tgaagctgga agaaatcgcg gctgacatta agagtggtaa
    13261 aaccacattt gccgcagcgg cgaaagagta ctctcaggac ccgggctccg ctaaccaagg
    13321 cggtgatttg ggttgggcta cgccagatat tttcgatccg gcgttccgcg acgcgctaac
    13381 gaagctgcat aaaggccaaa taagcgcgcc ggtacactcc tctttcggct ggcatctgat
    13441 cgaattgctg gatacgcgta aggtagacaa aaccgatgcg gcgcagaaag atcgcgctta
    13501 tcgtatgctg atgaaccgta aattctcaga agaagcggcg acctggatgc aagaacagcg
    13561 cgccagcgct tacgttaaga ttttgagtaa ctaatgagca gtgcgcaacg cgttgttatc
    13621 actcccggcg aacccgccgg gattggcccc gatcttgtcg tccaactggc gcaacgcgcg
    13681 tggccgattg aactggtcgt ctgtgcggac ggcgcgctcc tgacggagcg ggccgccatg
    13741 ctcggcctgc ccctctcgct tctcccttac tcgcctgatg tccccgctgc gccgcagccc
    13801 gcgggaacgc tgaccctatt gccggtctcg ctgcgcgcgc ctgccatccc cggtcagttg
    13861 acggtagaaa atggccccta cgtggtagag acgctggcgc gagcgtgtga tggctgtctg
    13921 aacggtgaat ttgccgcgct gatcacaggc cccgtgcaca aaggcgttat taacgacgca
    13981 ggcattccgt ttaccggtca taccgagttt ttcgaagagc gttcgcaggc gaaaaaagtc
    14041 gtgatgatgc tggcaaccga agaacttcgc gtggcgctgg cgaccacgca tctgccgcta
    14101 cgggcgattg cagacgccat cacccctgcg cttttgcacg aagtgattgc tattttgcat
    14161 cacgatttgc ggaccaaatt tggtattgcc gaaccgcgca ttcttgtctg tggcctgaat
    14221 ccgcacgcgg gcgaaggcgg tcatatgggc acggaagaga tagacaccat cattccggtg
    14281 ctcgacgagc tgcgggcgca ggggatgaaa ctcaacgggc cgctacctgc tgatacgctg
    14341 tttcagccca aatatctcga taatgccgac gcggtgctgg caatgtacca cgatcagggc
    14401 ctgcccgtgc taaaatacca gggattcggt cggggagtga atattacgct cggcctacct
    14461 tttattcgaa cctccgttga tcacggcacc gcgcttgaac tggcgggccg aggaaaagcg
    14521 gatgtcggca gttttattac ggcgcttaat ctcgccatca aaatgattgt taatacccaa
    14581 tgaataatcg agtccatcag ggccatttag cccgtaaacg cttcgggcaa aactttctca
    14641 acgatcggtt tgtgatcgac agtattgttt ctgctattaa tccgcaaaaa ggccaggcga
    14701 tggttgaaat cggccccggt ctggcggcgc tgacggagcc ggtcggcgaa cgactggata
    14761 agctcacggt cattgaactt gaccgcgatc tggcggcgcg tttgcaaacc catccgtttt
    14821 tagggccgaa gctgactatt tatcagcagg acgccatgac catgaacttt ggcgaactgt
    14881 ctgcgcagtt gggccagccg ctgcgtgtgt tcggcaatct gccctataat atctccaccc
    14941 cgctgatgtt ccatctcttt agctatactg atgccattgc cgacatgcac tttatgttgc
    15001 aaaaagaagt ggtaaatcgt ctggttgcag ggccgaacag caaagcgtat ggtcgtttaa
    15061 gcgtgatggc gcaatattac tgtcaggtga tcccggtgct tgaagtgccg ccatccgcct
    15121 tcacgccgcc gcccaaagtg gactccgccg tggtgcgtct ggttccacac gcaacgatgc
    15181 cttacccggt taaagatatt cgcgtgttga gccgtattac caccgaggcc tttaaccagc
    15241 gccgtaaaac gatccgtaat agtctcggca atctttttag cgttgagacg ttgacggaaa
    15301 tgggtattga cccggcaatg cgcgcggaaa atatctctgt cgcgcagtac tgccagatgg
    15361 ccaactatct gtcggaaaac gcgcctttga aggagagtta aacatgatca attcgcccag
    15421 agtgtgtatt caggtgcaaa gcgtctacat tgaggcgcaa tcctcacctg acgatgaacg
    15481 ttacgttttt gcctataccg taaccatccg caatctgggt cgggcgccag tgcagctatt
    15541 gggccgctac tggctgatta ccaatggtca tggccgtgaa actgaagtcc agggcaaagg
    15601 tgtggttggc gtccagccgc gcattgcgcc tggcgaagag tatcagtaca ccggcggcgc
    15661 ggtaattgaa acgccgctgg gcaccatgca gggtcattac gaaatgatcg atgaaaatgg
    15721 cgacgccttt accatcgaca ttcccgtgtt tcgactcgcc gtccctacac tcattcacta
    15781 aaattataac aatggcaact tatctcatcg gcgacgttca cggttgctac gacgaactga
    15841 tcgccttatt acagcaagtg gaatttacgc cagatacaga cactctatgg ctgactggcg
    15901 atttggtcgc ccgcggtccc ggttcgctgg acgtgttacg ctacgtcaaa tcgcttggca
    15961 atagcgtgcg tttggtgctg gggaatcacg atttacacct gttggccgta ttcgccggga
    16021 ttagccgcaa caaacctaaa gaccggctga ccccgcttct tgaagcgccg gacgccgatg
    16081 agctgttgaa ttggttacgc cgtcagccgc tgttgcaggt agatgaagag aaaaagctgg
    16141 tcatggcgca tgcgggtatt accccacagt gggatttgca gacggcaaaa gagtgcgccc
    16201 gcgatgttga agcggtgctg tcgagcgact cgtacccgtt tttcctcgac gcgatgtatg
    16261 gcgatatgcc gaataactgg tcgccggagt taagcggtct ggcgcggcta cgctttatta
    16321 ctaatgcctt tacccgtatg cgttactgct ttcctaacgg tcaactggat atgtacagca
    16381 aagcgtcgcc ggaaaatgcc cctgcgccgc tgaagccgtg gttcgccatt ccgggaccgg
    16441 tgagcgaggc ttacagtatt gctttcgggc actgggcgtc gctggaaggg aaagggacgc
    16501 cagaaggtat ttacgcgctg gataccggct gctgctgggg cggggagtta acctgtttac
    16561 gttgggaaga taaacagtat tttgtgcagc cgtcaaaccg ccagatggat atgggcgaag
    16621 gcgaagcggt caacgcctga taggtttatg cctgatggcg ctacgcttat caggcctaca
    16681 tccggctcaa gagtaggccg gataaggcat ttcgccgcca tccggcacta cagcgttaac
    16741 gacgctccag aatctcgaaa caatagctgt gagaattctg cgcgtcggca tcgtgaaact
    16801 cactgaatac cgattcccag tcatccggtt cataatccgg aaaatgggta tcgccttcga
    16861 cttccgcatc aatatgcgtc agataaagct tctgcgcctt tggcaggaac tgctcgtaca
    16921 cgcgcccgcc gccaatgacc ataatttccg gcgcatcgcc gcaagcggca atcgcctcat
    16981 cgacagactt cacccactgc acgcgatcgt cggtgcccgg ctggctgctg ataataatat
    17041 ttttacgtcc cggtaagggg cgtccgatgg actcccaggt gtgacgtccc atgacgacag
    17101 gtttatttaa cgtgttacgt ttaaaccatg cgagatcggc aggcaggttc cacggcatgg
    17161 cgttttccat accgatgacg cgatccaccg ctaacgccgc aatcagactg atcattaatt
    17221 atttcctgat acaaaaaaaa ttgccgccac tatacgtaaa gcgcaatctt tcgtcgactg
    17281 acgaaaagag gatgagcacg aaaatttttc gttctgctgg cgacgccact catttgatgt
    17341 ggagcgccag cattacagta gttcaaaaac agccaattag cagtaaagtt tgcagaacat
    17401 cacatttttt actttagatt gacggtttga cctcgggttc atcagcggcc ttcccggaat
    17461 gtttgccctc agccgttccc tgccagccgt ggcgctgaat caacgacaga tgctcccggt
    17521 cctcggtaat aatttcgctc aacatcgcgc tggtacgttt ataggcggcg gcgcgagata
    17581 acggatcgtt ttcccctttc gccatctctt ccaccatccg ggtattaaaa tgacagaaca
    17641 gatccgcgcg ctcgcgggct tcataacgcc ccagccccag cgcctccaaa gcctgtcgcc
    17701 cgcttttgag cgcgccttcg aaggtttcac gttcgggcat cgccacacca gcctggcgca
    17761 ggcgaatgta atgatcgaca tcacgggcgc gggcgataat ctgcagatgc gggaaatgcg
    17821 tcttcaccag ttcactcagt tgcaaattgg tttgcggatc gtcaatggcg ttaatcaata
    17881 cctccgcctt cgccgctccg gcagattcca gcaaatccat acgcgtcgcg tcgccataaa
    17941 aaaccttcat gccgaattta cgcagcgttt cgatatgatc ggggtcgtga tcgagcacca
    18001 ccatcttcac cccgctcgac agcagtaaac gcccggctat ctgcccaaat cgcccaaacc
    18061 cggccacaat gacccgcggc tgctcttcgt cgatttcatc cgcctcgcgc gcttcacccg
    18121 ttgcggtctt ttccatgcgc gtcagcagca ccagaaaaat cggcgtggcc gccatcgaca
    18181 gcgcgaccgc cagcgtcagc gcttttgccc attccggctc aagtacatcc gccatttgcg
    18241 ccgcgccaaa aaccacaaac gcaaactcac ttccctggcc taataagacg gcaaaccagc
    18301 gacgctgttt tgccggtacg cccagggtcc tcgcgaccag ccacagcatg acgattttga
    18361 ttgccagaaa accggccaac aacagcagaa tgcgcagcgg attctccacc agcgtgccga
    18421 aatcaatcga catgccgacg ccaataaaga acaaccccag cagcaacccc ttaaagggtt
    18481 caatatcgct ttccagcgca tgacgatatt ccgaactcgc cagcagaacg cccgccagga
    18541 acgcgcccat cgccattgac agcccaacct cttccagcaa caggccgaaa ccaaacacca
    18601 gaaatagcgc cacggcgctg aacacctccc gcaaaccaga acgcgcgaca aagcgcagcg
    18661 ccgggcgcgt aacgtagcgt cccagcaaca ccaccagcgc caacgcgcct gcgactttca
    18721 acgccgatag cgcaaacgcg ccaagcgtgg tggatgcgcc gctggcggcc agcagaggaa
    18781 tcatcgccac cagcgggatc gccgcgatat cctggaacaa gagcactgca aatgcgctac
    18841 gccctacctg tgaaacggtc aggttacgct cattcattgc ctgcatggcg atagccgtgg
    18901 acgaaagcgc cagcgtcatg ccaatcagtt ccgccacctg ccaacgcagg ccaagaaaca
    18961 tacagaacag accaatcagt ccgccgcaga ccaccatctg taacgcgccg ccgccaaata
    19021 ccgaggcgcg cagcttccat aaccgttgcg ggtccagttc aagcccaata acaaacaaca
    19081 tcagcacgac gccgatttcc gcaaaatgca gaatagattc ggcgtccgtc accagccgta
    19141 gcccccaggg gccgataatg caacccgcaa tcagataccc cagcactgat cctaagccca
    19201 aacgtaccgc aatcggcaca atcaacgccg ctgaaccaag atagatcagc gcctgcagta
    19261 gagtatggct atccatgatt cacctcctgc catgccagta aacgctgttt atactgacgc
    19321 gcctgcgcct gtaaggtgtc gtcatcgcaa atgaacgtgc agtgcatggc aaacggcggc
    19381 agccatttga ggccgcaata gagcgccgtc gcctgtagcg gctgagaaag gacggcaaat
    19441 cctggatggg agccgatagc aaagtggttt tcaccaccgc cggtcgttac cgcccacagc
    19501 agatgtttac catgcaatgc cgtaccgcca tgaccgtaag cccagccgtg ggtgaggact
    19561 ttatccatcc ataatttgag taaaggaggg acgctgtacc actgcatcgg atgctgccag
    19621 acgataagac tcgcgcgcga cagcgcctct tgctcggcgg ctacgtcaat attgaaatcg
    19681 ggatagaggt gataaagcga acgtatttcg acgttttcca gcgtccctgc ctgttcaagc
    19741 atctgcttat tcgcatgaga atgatgcgga tacggatgcg cataaataat gaggatcatg
    19801 attagcctgt gatgatctgt tttttatcac aaagtgtagt gacaaattcg ccaggctaat
    19861 agtgaatatt attgagcggc taatcagaaa aaattgaatt aacgccagca aggagttgac
    19921 gccatcctgc ccccggaaga tgccctcgaa gggccgcagg cgtttgtgga aaagcgcgat
    19981 ccggtgtgga aaggttggtg atgatggcag ccttaaattg ctgacaaatc ggtttaaggc
    20041 cttcttgtcg ggtggcgctg cgctaaattt tcctgtaatg actgtaatat caatccatta
    20101 catgatgaca caggcccaat aagcgcagcg ccaacagcat ctgaacctcc agacacgctg
    20161 gatgctagat caccgacgca taaattaacc taatgggtca ggctcttaat ctttcgccat
    20221 gcggttaaat tgctcaatag taagatccca tggctcacgg gccgcatccg gcataaaact
    20281 gccgtcatcc acgccaattt cgtctttgat aattttattc agtttttcat tcatcgtaag
    20341 aatgagatcc tgatatttct gtttatcagc agcaaggtta tggttctcat caggatcatt
    20401 tttaagatcg taaagttcaa gatcgttgta cttaataaga tcctcccagg tttccggcgt
    20461 attatgctcc cttagcgaga aatagcgtgc aaacttataa cggccatcgt taatcatccg
    20521 cgtccctgaa cgatggctga aatcaggatg caaatgcgat atttcctgct tgatttgcgc
    20581 caccgttttt gtttatctct ttgtagcgcg ataacacggt ggagataatg ggcatcggta
    20641 tacaagatca tgccatagca atataagctg gcatttctca ccgcattaac cgcaacgctc
    20701 tccgggtttt ttagcaatcc gctaaaatta acgcctttgc ggttgcctaa cgcctggtgc
    20761 tgtttttctt ccggcaaacc ggtcagccca actaatgtcg gcgcaatatc aagatgacag
    20821 gtcaacgcct gacatttctt attaccgggg tacgccgggt gggaaataat catcggtaca
    20881 tggatctgtt ctttataaac ggaagcgcct ttaccgtgca tctgatggct tccgcctaat
    20941 tcgccatgat cggcagtaaa tacaacaatc gttttatcag ttaacttgag ggcatccagt
    21001 tcatttaata tccggtcaag gtgagtatca caatcgcgga tacagttgaa atagtagtca
    21061 agcagtttac gccaacgacg atcttcatca ggaaactgcc cttccagcgc agcgcgcgcc
    21121 gtctggtatt caagatgcgc cggcggtctt ccctgctcat tgaatgattg atgcctgttt
    21181 gccggcagcg gatagttcgg ccagcttgcc tgataaagct cgttttccgg cggctgcgtg
    21241 ggcgccaggg tattatcatc ctgatccaac tcgccacgcc actgtacctt ttctccttct
    21301 ttatcggtat caataaacat gacgtcatga ggattaacga ggttaacggc caggaaccag
    21361 ggcttgtgtt ggtcattcaa gggctgcccc ttgcatctta accaatttat agtctgagcc
    21421 gtggtggttg aatcataaaa atagccgcct ttactatggc ctataatatc gccgatgccg
    21481 tgatagtcag caaaaccata tttttccata attttatgta attctggttc aggaatatcc
    21541 ccgacatcaa tatcctcatc tttttcgtca ggcaaaggct tctccagttt ttctgtaaga
    21601 tgccacttac ctttataggc cgtatagtat cccagttccc gcatcatatg gcctgtggtt
    21661 ccaagagcgg ggtcaaggtc ataaggcatc cagggtaatc ccagattatc aaacatcttt
    21721 gtctggggca tatgtaagcc ggtatacaat acggagcggg aaggcgtaca gacattactg
    21781 gtattctgat gattacagaa tgtcaccccc gttttcatga gccgctctct gccgggtaca
    21841 gggaaaggaa acgtaggaaa aaaacgctcc tagtcggtca cgactaacag aatattatat
    21901 ccttctggca atttttccgg gatttcgcca gtaaacggtt tatcccacgt cggtttcgcc
    21961 ttgacggcgc atttttcatc agcctttacc gcgccggata gcataccgcc ggcggcaaga
    22021 ataccgg
//
LOCUS       DAJVBX010000062        21755 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.062, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000062 DAJVBX010000000
VERSION     DAJVBX010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 21755)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21755)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21755
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.062"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            81..425
                     /locus_tag="OPV72_001989"
     CDS             81..425
                     /locus_tag="OPV72_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HCR9914293.1"
                     /translation="MYLNRFCYLLLISAAVGSIFTSYPVAMWFLLANVLTLAIYGVDK
                     TAARKTWRRVPESTLLVFGVVGGWPGAIVGQQLFRHKTQKQPFKTYFIASVIVSIVVT
                     VAIYRLYPFLSY"
     gene            complement(546..686)
                     /locus_tag="OPV72_001990"
                     /pseudo
     CDS             complement(546..686)
                     /locus_tag="OPV72_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460590.1"
                     /note="involved in bacterial survival in the host cell;
                     incomplete; partial in the middle of a contig; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pathogenicity island 2 effector protein SseJ"
     gene            687..1787
                     /locus_tag="OPV72_001991"
                     /pseudo
     CDS             687..1787
                     /locus_tag="OPV72_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460583.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            1836..3344
                     /locus_tag="OPV72_001992"
     CDS             1836..3344
                     /locus_tag="OPV72_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylesterase/lipase family protein"
                     /protein_id="HCR9914294.1"
                     /translation="MLNPSIPLVATRHGKIVGVVQEEIHIWRGIPYAAPPTGELRWRA
                     PQPVTPWQDVRQADCFSCASWQDITWCRELGGGDPGNFSEDCLYLNVWAPAVRHEPLP
                     VMVWLHGGGYTIGAGSLPPYDGQALAKRGAIVVTVNYRLGHLGFFAHPALEGEGAECI
                     HNFALLDQIAALRWVQDNIAAFGGDTQNVTLFGESAGARSVLSLMASPLAKGLFHKAI
                     IQSGYTLPDTPREVALKKGVALAEHLGLAHATAEQLRALPAETFWPLDAPFKIAPTPI
                     SGDVVLPHPMLETFFAAKQHPIPVMIGSNSDEASVLAVFGVDIAGQIQKMRRERRVGL
                     GLIRLLYPGVKGDEALGRQVCRDMVFTTLGYVVMQAQKRIGEPCWRYWFDYVAEAEHN
                     TYANSACHGNEIPYVFDTLTRAEPTCHYVNENDLAFASQVADYWVNFARHASRTRDVL
                     HGPVRWPASIRGRDRLLRIGLNKLAGFKVENRFMRARLALFKRVMKHHVSLE"
     gene            3564..5219
                     /locus_tag="OPV72_001993"
     CDS             3564..5219
                     /locus_tag="OPV72_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucan biosynthesis protein"
                     /protein_id="HCR9914295.1"
                     /translation="MNRRRFIKGSMAMAAVCGSSGIASLFSQAAFAAESDIADGKIVR
                     FDFAGLQSMAQALAKKPWGGAPGPLPDTLANLTPQAYNSIQYDAAHSLWNGVANRQLD
                     IQFFHVGMGFRRRVRMFSVDTTTHLAREIHFRPELFKYNDAGVDTTQLEGQSDLGFAG
                     FRVFKAPELARRDVVSFLGASYFRAVDDTYQYGLSARGLAIDTYTDGQEEFPDFTAFW
                     FDTAKPGDTTFTVYALLDSASVTGAYKFVIHCEKTQVIMDVENHLYARKDIKQLGIAP
                     MTSMFSCGNNERRVCDTIHPQIHDSDRLAMWRGNGEWICRPLNNPQKLQFNAYMDDNP
                     KGFGLLQLDRDFSHYQDVMGWYNKRPSLWVEPRSKWGKGAVSLMEIPTTGETLDNVVC
                     FWQPEKAIKAGDTLAFNYRLYWSAQPPVQSPLARVMATRTGMGGFPEGWAPGEHYPDK
                     WARRFAIDFVGGDLKAAAPKGIEPVITLSSGEAKQVEILYVEPFDGYRIQFDWYPTSD
                     STAPVDMRMFLRCQGEAISETWLYQYFPPAPDKRRYVDDRIMR"
     gene            5415..5990
                     /locus_tag="OPV72_001994"
     CDS             5415..5990
                     /locus_tag="OPV72_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenoid-binding protein"
                     /protein_id="HCR9914296.1"
                     /translation="MNIMKKSFLGALLSLGLLSAAHADVYKFDNTHTNAVFNIDRFQT
                     STNHGGFYAISGELKYQPEKQVAEMRVTIPVSALNTGVDAFDNHIRSSDILDAEKYPE
                     IVFKSTKWHFEDNKPVSIDGLLTMKGVTKPVTLTTTKFGCYMSPIFKAQVCGGDFVTQ
                     IDRTQWGVDYLVDMGMTKVVDIKIQAEAVKQ"
     gene            6002..7204
                     /locus_tag="OPV72_001995"
     CDS             6002..7204
                     /locus_tag="OPV72_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycolate oxidase"
                     /protein_id="HCR9914297.1"
                     /translation="MKTHHLIRVVASLAMLATSGLAYAEEYKASTDEKAIKMTNVASL
                     EARVQARMEKGAFGYIRGGAEDENNLRSNTESFDKKYIMPRVLQGIELKEIDLSTQLL
                     GIPLKTPIIQAPMAAQGLAHASGELATAKGMAQVGSIFSLSTYGNKTIEEVANVSGKN
                     PFFFQLYMSKNNQFNEFILAQAVKHGAKAIILTVDSPVGGYREEDIKNNFQFPLSFAN
                     LEMFARKNDDGSKTGKGAGISEIYAQAKQAFTPEDIAYVHRISGLPVIVKGIQSPEDA
                     EIAIQAGAAGIWVSNHGGRQLDSGPSSFDMLPAIAKVVNKRVPVIFDSGVRRGSHVFK
                     ALASGADIVAVGRPVLYGLNLGGAQGVASVIEQLNKELTINMMLGGARNIEQVKTTRL
                     LTEKDLPQ"
     gene            complement(7262..7696)
                     /gene="aac(6')"
                     /locus_tag="OPV72_001996"
                     /pseudo
     CDS             complement(7262..7696)
                     /gene="aac(6')"
                     /locus_tag="OPV72_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460578.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cryptic aminoglycoside N-acetyltransferase
                     AAC(6')-Iy/Iaa"
     gene            complement(7696..8487)
                     /locus_tag="OPV72_001997"
     CDS             complement(7696..8487)
                     /locus_tag="OPV72_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCR9914298.1"
                     /translation="MSQQRPDRIKQMLHYLWQHRHLSTQQAIELFGYAEATVRRDFHY
                     IASRYPGMVRGHGCIDFDDSTEDKEYVFDVKRTLQSEAKREIAALARTFIKDGDCFFL
                     DSGSTCLELAKCLVDAKVKVICNDIKIANELGGFPHVESYIIGGLIRPGYFSVGESLA
                     LEMINAFAVERAFISCDALSIETGITNATMFEVGVKTRIIQRSREVILMADHSKFDTV
                     EPHAVATLSCITTILSDSALPSAIARRYQQAGCRLIMSDPSSGAR"
     gene            complement(8503..9135)
                     /locus_tag="OPV72_001998"
     CDS             complement(8503..9135)
                     /locus_tag="OPV72_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3 epimerase family protein"
                     /protein_id="HCR9914299.1"
                     /translation="MILHPSLASADPLRYAEALTALHDAPLGSLHLDIEDTSFINNIT
                     FGMKTIQAVAQYSRHPLSFHLMVSSPQRWLPWLAAIRPGWIFIHAESVQNPSEILADI
                     RAIGAKAGLALNPATPLLPYRYLALQLDALMIMTSEPDGRGQQFIAAMCEKVSQSREH
                     FPAAECWADGGITLRAARLLAAAGAQHLVIGRALFTTANYDVTLSQFTAL"
     gene            complement(9147..9584)
                     /locus_tag="OPV72_001999"
     CDS             complement(9147..9584)
                     /locus_tag="OPV72_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCR9914300.1"
                     /translation="MINDVKWVQAQRHASDWRHALDIAVRPLITFGAAAPCYLDGIIE
                     NTLKWGPYYLIAPGIALPHARPEQGANHNQISVTTLSTPVAFGNADCDPIWLLLCASA
                     TDAEAHIRTIQRISQWLDSPESVAMLQDAPNDAALFAQLTALR"
     gene            complement(9716..10522)
                     /gene="sgcQ"
                     /locus_tag="OPV72_002000"
     CDS             complement(9716..10522)
                     /gene="sgcQ"
                     /locus_tag="OPV72_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BtpA family protein SgcQ"
                     /protein_id="HCR9914301.1"
                     /translation="MSWLKEVIGTEKAVIAMCHLRALPGDPGFDTRKGMNWVIDRAHD
                     DLMALQNGGVDAVMFSNEFSLPYLTKVRPETTAAMARIIGQLMSEIRVPFGVNVLWDP
                     VASFDLAMATDAKFIREIFTGAYASDFGVWDTNVGETIRHQHRIGAGHVKTLFNIVPE
                     AAVYLGNRDVCSIAKSTVFNNNPDALCVSGLTAGARTDSAILKRVKDTVPDTVVLANT
                     GVCLENVEEQLCIADGCVTATTFKKDGVFANFVDQARVAKFMEKVRHIRQ"
     gene            complement(10536..11849)
                     /locus_tag="OPV72_002001"
     CDS             complement(10536..11849)
                     /locus_tag="OPV72_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HCR9914302.1"
                     /translation="MFDYILSLGGTVFVPIIMIIIGLIFRIPWLQAVKAGVTVGIGFV
                     GMGLVIVMAIDSLSPPIKVMIERFGLTLHVFDVGAGPASGVGYATAIGAMIIPVIFLL
                     NVGMLVTRLTKTMNVDIYNYWHYAITGTVVQLMTGSLIYGVLGAICHAALSLKMADWT
                     TKRVQNIVGLEGISIPQGYGSSSVPLFVLLDAIYEKIPFMKGRNIDAQEIQKRYGMVG
                     DPVIIGVVLGLIFGLAAGEGFKGCATLMITVAAIMVLFPRMIRLIVEGLMPISDGARK
                     FFQKHFKGREVFIGLDTAVTLGHPTTIAVGLLLIPIMLILASILPGNKVLPLADLPVA
                     PFFICMATVIHRGDLIRTLLSGIIVMITVLLIATQFAPYFTDMALKGGFSFAAENAQI
                     TALSVGNMFGWSISELMSLGMIGVVIVVGIVASIILVLRKRELPE"
     gene            complement(11860..12141)
                     /locus_tag="OPV72_002002"
     CDS             complement(11860..12141)
                     /locus_tag="OPV72_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCR9914303.1"
                     /translation="MMKKILVACGTGMSTSTMIAQKLQDFLAEQGIAATTAQCCLNEI
                     PLNCNGMDLIVTSMRTHSDYGIPTLNGAALLTGINDDALKQEIKALLTQ"
     gene            complement(12138..13256)
                     /locus_tag="OPV72_002003"
     CDS             complement(12138..13256)
                     /locus_tag="OPV72_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HCR9914304.1"
                     /translation="MTFSVQETLFSLLRLNGISGHESSIANVMQHAFEQQAKDVWRDR
                     LGNVVARYGSDKSDALRLMIFAHMDEVGFMVRKIEPSGFLRFERVGGPAQITMPGSIV
                     TLAGCSGDIMGCIGIKAYHFAKGDERTQPPALDKLWIDIGAKDKADAERMGIQVGTPV
                     TLYNPPHCLGNDLVCSKALDDRLGCTALLGVAEALASTPLDIAVFLVASVQEEFNIRG
                     IVPVLRRVRPDLAIGIDITPSCDTPDLQDYSDVRVNHGVGITCLNYHGRGTLAGLITP
                     PRLLRMLETTAHENNIPVQREVAPGVITETGYIQVELDGIPCASLSIPCRYTHSPAEV
                     ASLRDLADCIRLLTALANMSPEQFPIDPETGATQEARP"
     gene            13473..14012
                     /gene="rimL"
                     /locus_tag="OPV72_002004"
     CDS             13473..14012
                     /gene="rimL"
                     /locus_tag="OPV72_002004"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12-serine
                     acetyltransferase"
                     /protein_id="HCR9914305.1"
                     /translation="MVEIIPVSTTLELRAADESHVPALHQLVLKNKAWLQQSLDWPQY
                     VTSQEETRKHVQGNMLLHQRGYAKMYLIFCQDEMAGVLSFNAIEPINKAAYIGYWLDE
                     SLQGQGIMSQSLQALMTHYARRGDIRRFVIKCRVDNQASNAVARRNHFTLEGCMKQAE
                     YLNGDYHDVNMYARIIDAD"
     gene            complement(14009..14989)
                     /locus_tag="OPV72_002005"
     CDS             complement(14009..14989)
                     /locus_tag="OPV72_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914306.1"
                     /translation="MIKYRLSEEPRAFTYQVDGEKKSVLLRQVIAVTDFNDVKAGTSG
                     GWVDADNVLSQQGDCWIYDENAMAFAGTEITGNARITQPCTLYNNVRIGDNVWIDRAD
                     ISDGARISDNVTIQSSSVRGECAIYGDARVLNQSEILAVQGLTHEHAQILQIYDRATV
                     NHSRIVHQVQLYGDATITHAFIEHRAEVFDFALIEGNKDNNVWICDCAKVYGHARVIA
                     GTEEDAIPTLRYSSQVAEHALIEGNCVLKHHVLVGGHAEVRGGPILLDDRVLIEGHAC
                     IQGEILIERQVEISGRAAVIAFDGNAIHLRGPKVINGEDRITRTPLVGSL"
     gene            15096..16109
                     /gene="tehA"
                     /locus_tag="OPV72_002006"
     CDS             15096..16109
                     /gene="tehA"
                     /locus_tag="OPV72_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate transporter/tellurite-resistance
                     protein TehA"
                     /protein_id="HCR9914307.1"
                     /translation="MCNHKQSDRVLNLPAGYFGIVLGTIGMGFAWRYASQIWAISHWP
                     GDIMVILAMIIWALLTLAFLSRLVRFPHSVMAEVRHPVMSSFVSLFPATTMLVAIGFV
                     PWYRPLAVALFSVGVVIQLAYAAWQTAGLWRGAHPEEATTPGLYLPTVANNFISAMAC
                     GALGYNDAGLVFLGAGVFSWLSLEPVILQRLRSCGELPAVLRMSLGIQLAPALVACSA
                     WLSVNGGEGDTLAKMLFGYGLLQLLFMLRLMPWYLSQPFNASFWSFSFGVSALTTTGL
                     HLGHGSESGFFHILAVPLFIFTNAIIALLLVRTFLLLVQGTLLIRTERAALLKTEEKN
                     DRS"
     gene            16096..16692
                     /gene="tehB"
                     /locus_tag="OPV72_002007"
     CDS             16096..16692
                     /gene="tehB"
                     /locus_tag="OPV72_002007"
                     /EC_number="2.1.1.265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tellurite resistance methyltransferase TehB"
                     /protein_id="HCR9914308.1"
                     /translation="MTVRDENYFTEKYGLTRTHSDVLAAAKVVAPGRTLDLGCGNGRN
                     SLYLAANGYDVTAWDKNPASMANLERIKAAEGLDNLQTDLVDLNTLTFDGEYDFILST
                     VVMMFLEAQTIPGLIANMQRCTKPGGYNLIVAAMDTPGFPCTVGFPFAFKEGELRRYY
                     EGWDMLKYNEDVGELHRTDENGNRIKLRFATMLARKTA"
     gene            16848..17516
                     /locus_tag="OPV72_002008"
     CDS             16848..17516
                     /locus_tag="OPV72_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3313 domain-containing protein"
                     /protein_id="HCR9914309.1"
                     /translation="MRTHTLFKVAVLTGLLALSGCASKVTQPDKYSGFLKNYSDLKET
                     TSATGKPVLRWVDPHFNDSNYDSIVYNPITYYPIPKPTTQVGQQVLDKLLAYTNTKVK
                     SAIEQRKPLVTTAGPRSLIFREAITGVDTSKEGLQFYEVIPVALIVAGTQMATGHRTM
                     DTHLYFEGELIDAATNKPVVKVVRQGEGKDLSNSSTPMAFETLKQVVDDMATDTSMFD
                     TNKK"
     gene            complement(17570..18748)
                     /locus_tag="OPV72_002009"
     CDS             complement(17570..18748)
                     /locus_tag="OPV72_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="benzoate/H(+) symporter BenE family transporter"
                     /protein_id="HCR9914310.1"
                     /translation="MRLLSLPLPTVLSGLVAVLVGYASSAAIIWQAALAAGATPAEIA
                     GWMTALGIAMGISTLTLTLWYRAPVLTAWSTPGAALLVTGLQGLSLPDAVGIFIVANA
                     LIVLCGVTGLFARLMRIIPHSLAAAMLAGILLRFGLQAFGTLNGEFVMCGGMLLAWLL
                     FKVFAPRYAVIAAMVMGITVALIQGKMAMSGIHFAPVWPTFVPPHFSFAQSLSVAVPL
                     FLVTMASQNAPGVATMKASGYQLPVSPLMIFTGLLALLLSPFGVYSICIAAITAAICQ
                     SPDAHPDPTRRWLAAAAAGVFYLLAGWFGGSITELMVALPVSWVQMLAGLALLSTISG
                     SLYQALTHESERDAAVIAFLVTASGLTLMGIGSAFWGLIAGGIGYAILTRTRRPSLSG
                     "
     gene            18840..19376
                     /locus_tag="OPV72_002010"
     CDS             18840..19376
                     /locus_tag="OPV72_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCR9914311.1"
                     /translation="MDNLTHYLATTLRTLRHQRGWSLSRLAEISGVSKAMLGQIERNE
                     SSPTVATLWKIATGLNVPFSMFISPPQAEFPPTFDPQQQAMVITPLFPWDPELCFDYF
                     SLLLAPGAVSESTPHKAGVIEHVVVIQGRLDMCTGGVWQTIDAGKGLRFAGDTAHTYR
                     NSSDQTVHFHSLIHYPRD"
     gene            19455..21419
                     /locus_tag="OPV72_002011"
     CDS             19455..21419
                     /locus_tag="OPV72_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HCR9914312.1"
                     /translation="MRQQPHYLELLSPARDAAIAREAILHGADAVYIGGPGFGARHNA
                     SNSLRDIADLVPFAHRYGARIFVTLNTILHDDELEPAQRLITDLYNTGVDALIVQDMG
                     ILELDIPPIELHASTQCDIRSVEKAKFLADVGFSQIVLARELNLSQIAAIHQATDATI
                     EFFIHGALCVAYSGQCYISHAQTGRSANRGDCSQACRLPYTLKDDQGRVVSYEKHLLS
                     MKDNDQTANLGALIDAGVRSFKIEGRYKDMSYVKNITAHYRQMLDAIIEQRGDLARAS
                     VGRTEHFFVPSTEKTFHRGSTDYFVNARKGDIGAFDSPKFIGLPVGEVLNVAKDYLDV
                     EATEPLANGDGLNVLIKREVVGFRANTVEKTGHNRYRVWPNDMPADLHKVRPHHPLNR
                     NLDHNWQQALTKTSSERRVAVDIMLGGWQEQLILTLTSEDGVCITHTLDGVFEEANNS
                     EKALNNLTAGLAKLGQTLYYARDMQVTLPAALFVPNSLLNQFRREAIDMLDAARLAHY
                     QRGRRKPVAQPAPVYPQTHLSFLANVYNHKAREFYHRYGVQLIDAAYEAHQEKGEVPV
                     MITKHCLRFAFNLCPKQAKGNIKSWKATPMQLVHGDEVLTLKFDCRPCEMHVIGKIKN
                     HILKMPQPGSVVASVSPEALMKTLLKRRGV"
     gene            complement(21420..21650)
                     /locus_tag="OPV72_002012"
     CDS             complement(21420..21650)
                     /locus_tag="OPV72_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2554 family protein"
                     /protein_id="HCR9914313.1"
                     /translation="MLTKTLSVVLLTCALFSGQLLAKQQDHAFVWFATGGHQLRHEAD
                     SDELRAAAEESAEGLREHHNWQKSRKPESYFR"
BASE COUNT         5186 a         5500 c         5869 g         5200 t
ORIGIN      
        1 agaaaattct gcatcacata ggcgcatgta tcgcgtataa tgggctccga tgtccctaat
       61 cattgctatg acataataat atgtatctta accgcttttg ttatttactc ctgatctctg
      121 ctgcggtcgg aagcattttt acatcgtatc ccgtcgcgat gtggttcctg ctcgccaatg
      181 tgctaacgct ggcgatctac ggtgtagata aaacggcggc acgtaaaacc tggcgcagag
      241 tgccggaatc cactttgttg gtgtttgggg ttgtcggtgg gtggcctggt gcgattgttg
      301 gtcaacaact tttccgtcat aaaacgcaaa agcagccatt caaaacatac tttatcgcca
      361 gtgtgatagt gagtattgta gttacggtgg cgatctatcg actctatcca tttttgtcct
      421 actgaacata gagtatggat cacttattga ccaaccggca gcaaagacaa cctcatattt
      481 tcatgtcacc ggcactatga tattgagcgg tgttttgctc aaggcgtacc gcagccgatg
      541 gaacattatt cagtggaata atgatgagct ataaaacttt ctaacattgt ggcaaaacaa
      601 tgatggactt cctgggttgg atggacaaag tcattgaaga cgtattgcgg acatatatct
      661 agctgagggt ctttagcccc gggaacttgc gtcggatatt cgccatcatg gggatgtacc
      721 cagtaagtta ttacgatctc tctcaggcgg gcgtgcctgt gcactccacg gcatttcgtc
      781 ccattgacga ggcttcgctc tcgcgtaatc cctttcgcat gttcacttcg ctattacgcc
      841 tggagctcat tgaaaacgcg gcattacgcc agcgggcggc ggaaatctta tcgcagcgtg
      901 atatttttac atcgcgctgc cgacaattgc tggatgagta cgacgagcag ggcggtttta
      961 gtgctgctca ggccgaagag ttcgtccgtg aaacgctgga gacttttcgc tggcatcgtc
     1021 aggctaccgt tgatgaagaa acgtaccgca gcctgcatcg tgagcatcgt ttaattgccg
     1081 acgtggtctg ttttccggga tgccacatta accatctgac gccgcgtact ctggatatcg
     1141 accgggtaca ggccatgatg ccggagtgcg gcattacgcc taaaattctt atcgaaggtc
     1201 cgcctcgccg cgaagtgcct attctgttgc ggcaaaccag tttcaaagct ctggaagagc
     1261 aggtgctctt cgttgatgaa aagcagggta cgcacacggc gcgcttcggc gaaattgagc
     1321 aacgtggcgt cgcgctgacg ccaaaaggtc gtcgattata tgacgaactg ttgcacaagg
     1381 cgggaacggg taaggacaac ttcacgcatc aactccattt gcgggaggtc tttaacgcct
     1441 ttccggatag cgaatttctg cttcgcctgc aggggcttgc ctggttccgt tatcgcttaa
     1501 cgccttccgg cgaggcgcat cgtcaggcga tccatcctgg cgacgatccg cagccgctta
     1561 ttgagcgcgg ttgggtgatc gcgcagccga ttacctatga agattttctt ccggtcagcg
     1621 cagccggcat ttttcagtcg aatttgggaa atgaaacgct ggccagaagc cacggcaatg
     1681 ccagccgcga cgcctttgaa caggcgctgg gatgtgctgt acgggatgaa ttttcgttat
     1741 atcaggaagc ggaagaacgc agtaaacgcc gttgcggtct gctttaaaag cggtaagctt
     1801 cacaggctgt gaggatactg taaaaggaag gcgttatgtt gaatccctcc atcccgctgg
     1861 tggcgacgcg tcacggtaaa atcgtgggcg tcgtacagga agaaatccat atctggcgcg
     1921 gtatacctta tgccgcgccg ccaacagggg agctacgctg gcgtgcgccg cagcctgtta
     1981 cgccctggca ggatgtgcgc caggcggatt gtttctcctg cgccagttgg caggatatta
     2041 cctggtgtcg cgaactcggc ggcggcgatc cgggaaattt ttccgaagac tgtctctatc
     2101 tgaacgtctg ggctcccgcc gtgcgtcatg aaccgttgcc ggtcatggtc tggctacacg
     2161 gcggcggtta caccattggc gcggggagtt tgccgcccta tgacggtcaa gcgctggcga
     2221 agcgcggcgc gatcgtggtg acggtcaatt atcggcttgg ccatctgggc tttttcgcgc
     2281 atccggcgct ggaaggcgaa ggggcggagt gtattcataa tttcgcttta ctcgatcaaa
     2341 tcgctgcgct gcgttgggtg caggacaata ttgccgcatt tggcggcgat acgcagaatg
     2401 tgacgttatt tggcgaatcc gccggcgccc gcagcgtgct gtcgttgatg gcttcgccgt
     2461 tggcgaaggg gctttttcat aaagcgatta ttcagagtgg ttatacgctg ccggatacgc
     2521 cccgcgaggt ggcgctaaaa aaaggcgttg cgctggcgga acatcttggt ttagcccatg
     2581 ccactgccga acagctacgc gctttaccgg cagagacgtt ttggccgctg gacgcgcctt
     2641 ttaaaattgc gccgacgccg atttccggcg acgtcgtgct gccgcatccg atgctggaaa
     2701 ccttctttgc ggcgaaacag catccaatac cggtgatgat cggctcgaat agcgatgaag
     2761 ccagcgtatt ggccgttttt ggcgtcgata ttgccggtca aattcaaaaa atgcgccgtg
     2821 agcggcgtgt tggcttgggg ttaatccggc tgctttatcc tggagtgaaa ggcgacgaag
     2881 cgctagggcg gcaggtctgt cgggatatgg tatttaccac gttgggttat gtcgtcatgc
     2941 aagcgcagaa gcggatcggc gaaccgtgct ggcgttactg gtttgattat gtcgccgagg
     3001 cggagcataa cacctacgcg aatagcgcct gtcatggcaa tgaaataccg tatgtattcg
     3061 atacgttaac gcgggctgag cccacatgcc attatgtgaa tgagaatgac ctggcctttg
     3121 cctcgcaggt ggcggattac tgggtgaatt tcgctcgtca tgccagccgc acgcgcgacg
     3181 tgctgcacgg cccggttcgc tggcccgcca gcattcgggg gcgagatcgt ctgttgcgga
     3241 ttgggctgaa caaacttgcc ggttttaaag tggaaaaccg ctttatgcgt gcgcgtctgg
     3301 cgctgtttaa acgagtcatg aaacatcacg ttagtctgga ataaactttt cataacctga
     3361 agaatgctgc gtgaggttta catccgattc ggtcggttct tatcgacata aaatatttac
     3421 gcttttgcac agtttccagg cgaccaacaa ttggattatt aatgaatttt gtctagagtg
     3481 agcggtcaga aacgggcaca ttcttgctgc tgaaaaaacc agcgcgggac cattcacaag
     3541 accagaagga ctcattttca ggtatgaatc gtagacgatt tattaaaggt tcaatggcaa
     3601 tggccgccgt gtgcggttcc agcggtattg cttcactctt ttctcaggcg gcgtttgccg
     3661 cggaatccga tattgcggat ggtaaaattg tccgttttga ttttgctggt ctgcaatcaa
     3721 tggcccaggc gttagcgaaa aagccctggg gtggcgcgcc gggacccttg ccggatacgc
     3781 tcgccaatct gacgccgcag gcctataaca gcattcagta tgacgcggcg cattcactct
     3841 ggaacggtgt tgccaaccgg cagctcgata ttcagttttt ccacgtaggg atgggcttcc
     3901 gtcgtcgcgt acgcatgttt tccgttgata cgacgacgca tcttgctcgc gagattcatt
     3961 ttcgcccgga actgtttaaa tacaacgatg ccggcgttga tacgacgcaa ctggaagggc
     4021 agagcgatct cggtttcgcc ggtttccgtg tctttaaagc gccggaactg gcgcggcgcg
     4081 atgtcgtctc cttcctgggc gccagttatt tccgggcggt agatgatact tatcagtatg
     4141 gcctgtcggc tcgcgggctg gcgatagata cctatactga cggtcaggaa gagttccctg
     4201 acttcaccgc attctggttt gacaccgcga agccgggcga tactacgttt accgtttacg
     4261 ctctgctgga cagcgccagc gtgacgggcg cgtataagtt tgtgatccat tgcgaaaaaa
     4321 cgcaggtgat catggatgta gaaaaccatc tctacgcccg taaagatata aagcaacttg
     4381 gcattgcgcc gatgaccagt atgtttagct gtgggaataa tgaacgccgg gtatgcgaca
     4441 ccattcatcc gcaaattcac gattccgatc ggctggcgat gtggcggggt aacggcgagt
     4501 ggatttgccg cccgctgaat aatcctcaga aattacagtt caacgcatat atggacgata
     4561 acccaaaagg gttcggcctg ctgcaactcg atcgcgattt ctcgcattat caggatgtca
     4621 tgggctggta caacaaacgt ccgagcctgt gggtggagcc gcgcagtaag tgggggaaag
     4681 gcgcggttag cctgatggag atcccaacca ctggcgaaac tctggataat gtggtctgtt
     4741 tctggcagcc ggaaaaagcg atcaaagccg gggatacgct ggcgtttaat tatcgtttgt
     4801 actggagcgc gcagccgccg gtacaatcgc cgcttgcgcg ggtcatggcg acccgtacag
     4861 ggatgggcgg ctttcccgaa ggctgggcgc cgggcgaaca ttacccggat aaatgggcac
     4921 gccgttttgc tattgatttt gtcggcggcg atctgaaagc ggccgcgcca aaaggcattg
     4981 agccggtaat tacgctctcc agcggtgagg cgaagcaggt tgagatcctc tacgtagagc
     5041 ctttcgacgg ttatcgtatc cagtttgact ggtatccgac ctcggattct acggcaccgg
     5101 tggatatgcg tatgttcctg cgctgccagg gggaggctat cagcgaaacc tggctgtatc
     5161 agtatttccc gcccgcgccg gataagcgcc gttatgtcga cgatcgtatc atgcgttagt
     5221 cagtttgcct tctgtaccgc cacaaaggcg gtacaggttg cggaaattgc catgacataa
     5281 acccattcgt gagccgctgt ttttgtgaca cggccttttc atcgttctat ttttgcaaca
     5341 gtccttcctg tttatccctc tcgatcctgc ggacagggga cattaagata gcttcacctt
     5401 atttaagata taaagtgaat ataatgaaaa agagttttct tggtgctctc ctgtctctgg
     5461 gtttattaag tgctgctcat gcagatgtat ataaatttga taatacgcat accaatgcgg
     5521 tatttaatat cgatcgtttc cagacctcaa ccaatcatgg cgggttttat gctattagcg
     5581 gcgaactgaa atatcagccg gaaaagcaag tcgcagagat gcgtgtgacg attcccgtga
     5641 gcgccttaaa taccggggtg gatgcgtttg ataaccatat tcgcagtagc gatattttgg
     5701 atgcggaaaa atatccagaa atagtattta aatcgacaaa atggcatttt gaagataata
     5761 aaccagtttc tattgacggt ttgttaacaa tgaagggagt aactaagccc gtcaccttaa
     5821 ccaccaccaa gtttggctgt tatatgagcc cgatattcaa ggcgcaggtt tgcggtggtg
     5881 attttgtcac gcaaatagat cgcacccagt ggggtgtaga ttatctggtc gatatgggga
     5941 tgacgaaagt tgtcgatata aaaatccagg cagaagcggt taagcaataa aaggaataat
     6001 gatgaaaact catcacctca ttcgggtagt ggcctcgctg gcaatgttgg caacatcagg
     6061 cctggcttat gctgaagagt acaaagccag cacggacgaa aaagcaataa aaatgacgaa
     6121 cgtagcctct ctggaagcgc gcgttcaggc cagaatggag aaaggggcat ttggttatat
     6181 tcgcggtgga gccgaagatg agaataacct tcgcagcaac accgaaagct ttgacaaaaa
     6241 atatattatg ccgcgcgtat tacagggcat tgagttaaaa gagatcgatt tatcaacgca
     6301 gctactgggt attccgctta aaacgcctat aatccaggca ccgatggcgg cgcagggcct
     6361 ggcccacgcc tccggagagt tggcgacggc gaaaggcatg gcgcaggtcg gttcgatttt
     6421 ctcgttgagc acttatggca acaagaccat cgaagaggtg gctaacgttt ccgggaaaaa
     6481 cccgttcttc ttccagcttt atatgagtaa gaataatcaa tttaacgaat ttattcttgc
     6541 acaagcggta aaacatggcg ctaaagcgat tattctgacc gtagattcac ctgtcggcgg
     6601 ttatcgggaa gaagatatta aaaataactt ccagttcccg ctgagttttg caaacctgga
     6661 aatgttcgcc aggaaaaatg acgatggttc aaaaaccggc aaaggggcag ggataagtga
     6721 aatttacgcg caggctaaac aagcctttac gccggaggat attgcctatg tacatcgtat
     6781 ttccggtctg ccggttattg taaaaggcat tcagtcgccg gaggatgctg aaattgctat
     6841 ccaggctggg gccgcaggaa tatgggtttc taatcatggt ggccgtcaat tagacagcgg
     6901 gccgtcctca ttcgatatgc ttcctgcgat tgcaaaagtc gtcaacaagc gagtgcctgt
     6961 tatttttgac agtggagtac gccgtggttc gcacgtattc aaggcgttag ccagcggggc
     7021 ggatattgtg gcggttggcc gacctgtatt atacggtctt aatcttggcg gcgctcaggg
     7081 tgtggcatca gtgattgaac agctaaacaa agagctgaca attaacatga tgttgggtgg
     7141 cgccaggaat attgaacaag tgaaaacgac acgcttgtta actgaaaaag atctgccaca
     7201 gtaatacagt aatatagagg tcgggtatta tacccgacct tttcctgtgt gattttcctc
     7261 gacaacgctt tcggtagaaa atgacgcgct ctgtttcctc aaatcctaac gccaggtgaa
     7321 ctttctgtga aattgtattt tccggcgagg tatcggaagc catttcccga caccctttat
     7381 tcgttcccca tcgttgcact gctgctatca attgtttcgc taagccgcgt tgacggaacg
     7441 aggggagaac aaaaatacct tcaaggaaaa ccacgggcga actgtcacag ccattgacat
     7501 aatcgtggcg gattgaggca tccgcaaagc caatcgccac cccgtctgcc atcgcaataa
     7561 atgatgccag atgttcggct tgcagaattt cttcgccgtc cgccagatgg gcgtcatccg
     7621 ggtgaccagg ccagagctgt tttcgcaatc cgcgccagtg ctccagatgg gttttgttca
     7681 tttgcctgat gtccattaac gcgctcctga tgaggggtct gacatgatga gacggcatcc
     7741 cgcctgctga taacgtcggg cgatagcaga cgggagcgca ctgtcgctaa gaatggtagt
     7801 aatacaggac agcgtcgcca ccgcatgggg ttctacagta tcaaactttg aatgatcggc
     7861 catcaatatg acctcgcgtg agcgctgaat aatgcgcgtt ttgacgccta cttcaaacat
     7921 ggtagcgttg gtgatgcccg tttcaatcga cagcgcatcg caagagataa aggcgcgttc
     7981 aacggcaaag gcgttaatca tctccagcgc cagactctcg cccaccgaaa agtagccggg
     8041 gcgaatcagt ccgccaataa tgtagctctc tacgtgtggg aagccaccca gttcgttagc
     8101 gattttgatg tcattgcaaa tgacttttac tttggcgtcg accagacatt ttgccagttc
     8161 cagacaggtg gagccagagt cgagaaaaaa gcagtctcca tccttgatga acgtgcgggc
     8221 gagggcggca atttcgcgtt tcgcctcgct ttgtaacgtc cgcttaacgt cgaaaacata
     8281 ttctttatct tccgtactgt cgtcaaagtc aatacaacca tggccgcgaa ccataccggg
     8341 ataacggctg gcgatatagt gaaaatcccg gcgcacggtt gcctctgcat agccaaaaag
     8401 ctcaatagct tgttgtgttg agaggtgcct gtgttgccaa aggtaatgca acatctgttt
     8461 gatacggtcg gggcgctgtt ggctcatcag catatgactc ctttatagcg cggtgaattg
     8521 tgacaatgtc acatcatagt tcgccgtcgt gaacaacgcc cggccaatca ccagatgctg
     8581 ggcgcctgcg gcggcaagca gccgtgcggc gcgaagtgta ataccgccgt ccgcccagca
     8641 ttccgcagca gggaaatgct ctctgctctg gctcactttt tcacacatcg cggcaataaa
     8701 ttgttgcccg cgcccgtcgg gttcgctggt catgatcatc agcgcatcca gttgcaatgc
     8761 cagataacga taaggcaata gcggtgttgc cgggttaagc gccagtcctg ctttcgcccc
     8821 gatagcgcga atatccgcca gaatctccga ggggttttgc acgctttcgg catgaatgaa
     8881 aatccagccg gggcggatag ctgcaagcca gggtaaccag cgttgcggtg atgaaaccat
     8941 caggtgaaat gagagcggat ggcgagagta ttgcgcgacc gcctgaatgg ttttcatacc
     9001 gaaggtaata ttgttgatga aactggtatc ttcgatatcc agatgcagcg agccgagagg
     9061 cgcatcgtgt aaagcggtca acgcctcggc atagcgcagc ggatcggcgg aggccagtga
     9121 agggtgcagg atcatcggaa ccttcatcag cgcaatgcgg ttaattgcgc gaaaagcgcg
     9181 gcatcatttg gcgcatcttg caacatcgcg acgctttccg gcgagtcgag ccactggctg
     9241 atgcgttgaa tggtgcgaat atgtgcttcg gcatccgtgg cgctggcgca aagcaacagc
     9301 cagatgggat cgcaatccgc attgccgaaa gcgaccggcg ttgatagcgt agtgacgctg
     9361 atttgattat ggttggcgcc ttgctctggt ctggcatggg gcagcgcaat ccccggcgcg
     9421 ataagataat atggccccca tttaagggtg ttctcaataa taccgtccag gtagcagggg
     9481 gccgccgcgc cgaaggtaat cagcggacga acggcgatat ccagcgcgtg tcgccagtcg
     9541 ctggcatggc gttgcgcctg aacccactta acatcattaa tcatcgatcg ttgactcctt
     9601 gccggttcgg gttactctga aaccgatccc cggcgtgtct tttggcgaag gcgacggaga
     9661 tcggcagaag agttatcgct ctctgcaggg gataagcgtt ttgcttatcc ccattttatt
     9721 gtcggatatg gcgtactttc tccataaact tcgccacgcg cgcctggtcg acaaagttgg
     9781 cgaagacgcc gtctttttta aacgtggttg ccgttacgca tccgtcggca atgcagagct
     9841 gctcctcgac gttttccaga cacaccccgg tattcgccag cacgaccgtg tcgggaacgg
     9901 tatcttttac ccgcttcagt atggcgctat ccgtgcgggc gcccgccgtc agccccgaga
     9961 cgcacagggc atcggggtta ttgttaaata cggtcgattt cgcaattgaa cagacatctc
    10021 ggtttcccag atacaccgcc gcttccggca cgatgttaaa cagcgttttc acgtggcctg
    10081 cgccgatgcg atgctgatgg cgaatagttt cgccgacatt cgtatcccag acgccaaaat
    10141 cgctggcgta agcaccggtg aaaatttcgc gaataaattt tgcgtcggtc gccatcgcca
    10201 aatcaaaaga ggccacaggg tcccacaaca cgtttacccc aaacggtacg cgaatttcac
    10261 tcattaactg accgatgatt cgtgccatcg cggcagtcgt ttccggtctg actttcgtta
    10321 aataaggcag actaaattcg ttggagaaca tcaccgcatc cacgccgcca ttttgtagcg
    10381 ccattaaatc gtcatgggcg cggtcaatta cccagttcat gcctttcctg gtatcgaacc
    10441 cgggatcgcc cggcagcgcc cgtaaatggc acatggcgat aacggctttt tctgttccta
    10501 ttacctcttt tagccaactc attctgggtt gctccttatt ccggtagttc acgtttacgt
    10561 aagacaagta tgatgctggc gacaatgccg accacaataa ccacaccaat catgcccagc
    10621 gacatcaatt cagatattga ccagccaaac atatttccca ccgacagcgc ggtaatttgc
    10681 gcgttttcag cggcgaagct aaagccgcct ttgagcgcca tatcggtaaa gtacggcgcg
    10741 aactgggtgg cgatcagcaa aacggtaatc atgacaatga tgccgctgag cagagtacga
    10801 atcagatcgc cgcgatgaat aactgtggcc atgcagataa aaaatggcgc gaccggtaaa
    10861 tcagccagcg gcaggacttt attgcccggc agtatgctcg ccagaattaa catgatggga
    10921 attaacagca gtccaaccgc gatggtggtc gggtggccta acgtcactgc ggtatccaga
    10981 ccgataaaga cttcgcgccc tttaaagtgt ttctggaaga acttacgcgc gccgtcggaa
    11041 atgggcatta atccctcaac gataaggcga atcatgcgcg gaaacagcac cataatcgcc
    11101 gccacggtaa tcattaaggt tgcgcaccct ttaaagcctt cgcctgcagc aagtccgaag
    11161 atcagcccga gaacaacgcc aatgatcacc gggtcgccga ccatcccata ccgtttttgg
    11221 atctcctgag cgtcaatatt gcgtcctttc ataaacggta ttttttcgta tatcgcatcc
    11281 agcaatacga acaacggcac ggagctggag ccataccctt gcggaataga aatcccttcc
    11341 agacccacaa tgttctgtac ccgtttcgtc gtccagtcgg ccattttcaa cgacaaggcg
    11401 gcatggcaaa tcgcgcccag tacgccataa atcagactgc cggtcatcaa ctggacgacc
    11461 gttccggtaa tggcgtagtg ccagtagtta taaatatcaa cgttcatggt tttggtcaga
    11521 cgagtcacca gcataccgac gttgagcaga aagataacgg gaatgatcat cgcgccgatg
    11581 gccgtcgcat agccgacgcc ggatgcgggc ccggcgccga cgtcaaacac atgcagcgtc
    11641 aggccaaaac gctcaatcat cactttaatc ggcggactga gactgtcgat cgccatgacg
    11701 atcaccagcc ccatgccgac aaaaccgatg ccgaccgtca cccccgcttt caccgcctgc
    11761 agccagggaa tacgaaagat taagccgatg ataatcataa tgatgggcac aaagacggtg
    11821 ccgccgagag acaggatgta atcaaacata atgccccctt tattgtgtta acagcgcctt
    11881 gatttcttgt tttaatgcgt cgtcgttgat gcctgtcagc agggcggcgc cgttgagcgt
    11941 cgggatgcca tagtcactgt gcgtacgcat ggacgttacg atgagatcca taccgttaca
    12001 gttcaacggg atctcattca gacaacattg cgccgtggtt gccgcaatgc cttgctccgc
    12061 aagaaagtcc tgcagttttt gtgcaatcat ggttgatgtc gacatgccgg taccacatgc
    12121 cacaaggatc tttttcatca tggtcgtgcc tcttgtgtag cgcctgtttc agggtcaatg
    12181 ggaaactgtt ctggcgacat attggccagc gcagtcagta aacggataca atcagccagg
    12241 tcgcgcaggc tggcgacttc ggctggcgag tgggtatagc ggcagggaat agaaagactg
    12301 gcgcagggaa taccgtccag ttcaacctga atgtagcctg tttcggtgat gacgcctggc
    12361 gcgacttcac gctgtacggg aatattattt tcgtgcgcgg tggtctccag catccgcagc
    12421 aaacgcggcg gcgtaatcag tcccgccaac gtaccgcgtc cgtgatagtt cagacaggtg
    12481 atgccgacgc cgtggttgac ccgcacatcc gagtaatcct gcaggtcagg cgtgtcgcag
    12541 gagggggtga tatcaatacc aatcgccagg tcggggcgca cgcgtcgtaa aacgggaaca
    12601 atcccgcgaa tattgaactc ttcctgtacc gacgcgacca ggaataccgc gatatcaagc
    12661 ggtgtggagg cgagggcctc ggcgacgccc agtagcgccg tacaccccag cctgtcatcc
    12721 agcgccttac tgcacaccag gtcgttgccc agacagtgcg gcgggttgta aagggttact
    12781 ggcgtcccca cctgaatacc cattcgttcg gcatccgctt tatcttttgc gccgatatca
    12841 atccagagtt tatcgagcgc gggtggctgg gtgcgctcgt cacccttcgc gaagtgatat
    12901 gctttaatac cgatacagcc catgatatcg cctgaacatc cggcaagcgt cacaatcgaa
    12961 ccgggcatag taatttgcgc cgggccgccc acgcgttcaa aacgtaaaaa accggagggt
    13021 tcgatcttgc gtaccataaa acccacttca tccatatgcg caaaaatcat caggcgaagc
    13081 gcgtcggatt tatcgctgcc ataacgggcg acgacattac ctaagcgatc ccgccagacg
    13141 tctttggcct gctgttcgaa cgcgtgctgc ataacgtttg caatactgct ttcatgtcct
    13201 gaaatcccgt ttagccgcag taaagaaaaa agcgtttcct gcacagaaaa ggtcattggc
    13261 gtctccgtgg tgataaaaca atcagtcgtt gagcgtttta taggcggaga atggttggat
    13321 aagtgtgaaa tgtgtcacgc ggaaatacgc taaatatggt caataaaaaa taatgtgatg
    13381 gcgatacaat aaaaacgctc atatcacctg cgggttatcg gtaaaccagg ctatttatgt
    13441 gatcacgacc aacaacgaag aagggcaacg cgatggtgga aattattcct gttagcacga
    13501 cgctggaact gcgagcggca gatgaaagtc atgttccggc gctgcaccaa ctggtactca
    13561 aaaacaaagc gtggctacaa cagtcgctcg actggccgca atatgtcacg tcgcaggagg
    13621 aaacgcgtaa gcatgtgcag ggtaatatgc tgttgcacca gcgtggttac gccaaaatgt
    13681 acctgatttt ctgccaggat gagatggcgg gcgtactctc atttaatgcc atcgagccga
    13741 taaacaaagc cgcctatatc ggttactggc tggatgagtc ccttcagggg caagggataa
    13801 tgtcgcaatc attacaggcg ctgatgacac attatgcccg gcgcggcgat attcggcgct
    13861 tcgtcattaa atgccgcgtt gataatcagg ccagtaacgc ggtcgcacgg cgcaaccatt
    13921 ttacgctgga aggctgtatg aaacaggcgg agtatcttaa cggcgactat cacgacgtta
    13981 atatgtatgc ccgcattatt gatgcggatt aaagagaacc gactaagggg gtacgcgtaa
    14041 tacgatcttc tccattgatc acttttgggc cgcgtaggtg aatagcattg ccgtcaaacg
    14101 ctatcaccgc cgcccgtccg ctaatctcga cctggcgctc aatcagaatt tcgccctgta
    14161 tacaggcatg gccttcaatc agcacgcggt cgtccagtaa aatcggacct ccgcgtacct
    14221 cagcatgtcc gcctaccagc acatgatgtt ttaacacaca gttgccttcg attaacgcat
    14281 gttccgctac ctgcgagctg tagcgaaggg tagggatagc atcttcctct gtgccggcga
    14341 taacccgcgc atggccatag actttggcgc agtcacagat ccagacatta ttgtctttgt
    14401 tgccttcgat gagcgcgaaa tcaaagacct ccgcccggtg ctcaataaaa gcgtgagtga
    14461 tagtggcgtc gccataaagc tgtacctgat ggacaatccg cgaatggttc acggtggcgc
    14521 gatcgtaaat ttgtaaaatc tgcgcatgtt catgcgttag tccctgaaca gcgagaattt
    14581 ctgactggtt taacacgcgg gcatcgccat aaatcgcaca ctctccacgc acggaagagg
    14641 actgaatggt gacgttgtca cttatccgtg cgccatcgct gatatcagcg cgatcaatcc
    14701 agacgttatc gcctattcgc acgttattgt agagcgtgca cggctgcgtg atacgcgcgt
    14761 tacccgtaat ttccgtgccc gcaaaggcca tcgcgttttc atcataaatc cagcaatccc
    14821 cctgttgtga cagcacatta tcggcatcaa cccagccgcc ggaggttccg gctttaacat
    14881 cgttaaaatc cgttacggca ataacttgtc gtaataagac gcttttcttc tcaccgtcta
    14941 cctgataagt aaaagcacga ggttcttcac tcagtcgata tttgatcata gggaaattcc
    15001 gtgtgaacga ttaagataac cgtagcaaag gtactggcga aacaaccaga aattccataa
    15061 aatgcatttc aaatatactt tataaattaa acaaaatgtg taatcacaag cagagcgatc
    15121 gcgtgctcaa tctgcctgcg ggctattttg gcatcgtcct tggcactatc ggtatgggat
    15181 tcgcctggcg ttatgccagc cagatatggg caataagcca ctggcccggc gacatcatgg
    15241 tgatcctggc gatgattatt tgggcactct tgaccctggc gttccttagc cgtctggtgc
    15301 gctttcccca tagcgtgatg gctgaagtgc gacatccggt aatgagcagt tttgtcagcc
    15361 tgtttcccgc caccacgatg ctggtcgcga tcggtttcgt tccctggtat cgcccgttgg
    15421 ccgttgcgct attcagcgtg ggggtcgtca tacaactggc gtatgccgcc tggcagacgg
    15481 cgggtctttg gcgcggagcg catccggaag aagcgacaac cccaggactt tatctgccca
    15541 cggtagcgaa taattttatc agcgctatgg cctgtggagc gctcggttac aatgatgccg
    15601 gactggtgtt tttaggcgca ggcgtctttt cgtggttaag tctggaaccg gttattttgc
    15661 agcgactgcg tagctgcggc gaattaccgg cggtgctgcg tatgtcgctg ggtatccaac
    15721 tggcgcccgc gctggtcgcc tgtagcgcct ggctgagcgt caatggcggg gagggcgaca
    15781 cgctggcgaa aatgctattc ggctacggtc tgttacagct tttatttatg ctgcgattaa
    15841 tgccctggta tttatcacaa ccgtttaatg cttccttctg gagtttttcg ttcggcgttt
    15901 ccgcgctgac gaccacgggg ttacatcttg gtcacggtag tgaatcaggg tttttccata
    15961 ttctggccgt cccgctgttt attttcacta acgctattat cgccttattg ctggttcgta
    16021 catttctatt gctggtgcag gggacgttgc ttattcgcac tgagcgcgct gcactgttga
    16081 aaacggagga aaaaaatgac cgttcgtgac gaaaattact ttactgagaa atacggttta
    16141 acccgcacgc attcggatgt gctggcggcg gcaaaggttg tcgcgccagg ccgaacgctg
    16201 gatttgggat gtggcaatgg ccgtaatagt ctgtatctgg ccgcgaacgg ttatgacgtt
    16261 accgcgtggg ataaaaatcc ggccagtatg gctaaccttg agcgtattaa agcggcagaa
    16321 gggctggata atctgcaaac cgaccttgtc gatctgaata cattgacctt tgacggcgaa
    16381 tacgatttta ttctctcgac agtggttatg atgtttcttg aggcgcaaac cattcccggt
    16441 ttaattgcca atatgcaacg ctgcacaaaa cccggcgggt ataatttgat tgttgcggca
    16501 atggatacgc cgggctttcc ctgtacggtg ggattcccgt tcgcttttaa agaaggcgaa
    16561 ttacgccgct attacgaagg atgggacatg ctgaaataca acgaagatgt cggcgagctt
    16621 caccgcacgg acgaaaacgg caaccgtatc aaactgcgct ttgctacgat gctggcgaga
    16681 aaaacggcct gagcgatgca agttctgtaa gtcttgctgc gttcggcatt tttttgtcgg
    16741 gcgccgcgtt caaattgtgc tgtcgttacc atttttagtg catccagaat gatttcgttt
    16801 tgctattatt tcctttgcat cattgcgaag actaaaggga tcgtttcatg cgtactcata
    16861 ctttatttaa agttgcagtg cttactggct tgctggcgtt atccggctgt gcgtctaaag
    16921 tcacacagcc ggataagtat tctggattct taaaaaatta ttcggacctg aaggagacta
    16981 cttccgccac ggggaaaccg gtgttgcgct gggtagatcc acattttaat gactctaact
    17041 atgacagtat tgtttacaat ccgataacat attaccccat ccccaagcca acgacccagg
    17101 tcggacagca agttcttgat aaactgctgg cttatacgaa cactaaagta aaatcagcaa
    17161 ttgaacagcg caaaccgctg gtcacgacgg cagggccgcg cagtttgatt ttccgcgagg
    17221 cgattacggg cgtggatacc agcaaagaag ggctgcaatt ctatgaggtg atccctgtag
    17281 cgctgattgt ggcgggcacg caaatggcga cgggccaccg gaccatggat acccacctct
    17341 attttgaggg tgagctgata gatgccgcga ccaacaagcc ggtcgtcaag gtagtgcgcc
    17401 agggcgaagg taaagacctg agtaattcca gtacgccaat ggcgtttgag acgttgaaac
    17461 aggttgtgga tgatatggcg acggatacct ctatgtttga cactaacaaa aaataattct
    17521 gcggcgccat cgcaagatgg cgcaaacccc ggcagattag cggccgccat cagccagaca
    17581 acgacgggcg gcgcgttctc gttaatattg cgtagcctat cccgccagcg atcaaccccc
    17641 agaatgccga tccgatgccc atcagcgtta gcccgctggc ggtgacgaga aatgcgataa
    17701 ctgccgcgtc acgctcactt tcgtgagtaa gcgcctgata cagactaccg ctaatcgtac
    17761 ttaacagtgc cagaccagcc agcatttgca cccagctaac cggtagggcg accatcagct
    17821 cggttatcga accgccaaac cacccggcaa gtaaataaaa aacgcctgcg gcggcggccg
    17881 ctaaccagcg acgcgttgga tcggggtgcg cgtccgggct ttgacaaatg gcggctgtaa
    17941 tggcggcaat gcagatagaa taaacgccaa acggcgaaag cagcagcgcc agtaatccgg
    18001 taaaaatcat taacggagag acaggaagct gatagccaga cgccttcatt gtggcgacgc
    18061 cgggggcgtt ttgcgatgcc atcgtcacca ggaagagcgg taccgcgacg ctcaggcttt
    18121 gagcgaatga aaagtggggg ggaacgaagg tgggccacac cggcgcgaaa tgaataccgc
    18181 tcatcgccat cttaccctgg atgagcgcca ccgttattcc catcaccatg gcagcaataa
    18241 cggcatagcg gggcgcgaat actttaaaga gtagccacgc caatagcata ccgccgcaca
    18301 tgacaaactc tccgttgagc gtcccgaacg cctgcaggcc gaagcgtagc agtattcccg
    18361 ccagcattgc ggcggcaaga gaatggggga ttatccgcat caaacgcgca aacaatcccg
    18421 tgacgccgca cagcacaatc agggcattgg cgacaatgaa tatgcccacg gcgtctggca
    18481 acgataatcc ctgaagccct gtcaccaaca gagcggcgcc aggcgttgac caggcggtta
    18541 aaaccggcgc acgataccac aaggttaacg ttagtgtgct tatgcccatg gctataccga
    18601 gggcggtcat ccagccggcg atctctgcgg gtgttgcgcc agcggcaagc gccgcctgcc
    18661 agataatggc ggcggaactt gcatagccga ccagaacggc gaccagacca gataatacag
    18721 taggtaacgg cagtgataac agacgcatga tcgcctcttg tgcgttataa cggtcagtca
    18781 atgtagcatt gtgcgttata gcgtacaagt gatacgctat ggccttacag gggggaaaaa
    18841 tggataacct gacacactat ctggcgacca cgttaagaac gttacgccat cagcgaggct
    18901 ggagtttatc acgtctggcg gagatctccg gcgtctcaaa agccatgttg gggcagatag
    18961 agcgtaatga atccagtccg acagtcgcaa cgctgtggaa aattgcgacg ggcctgaacg
    19021 ttccattctc aatgtttatt tcgccgccgc aggccgaatt tcctccaacc ttcgatcccc
    19081 agcagcaagc gatggtaatc acaccgctgt ttccgtggga ccctgaactc tgttttgact
    19141 atttttccct attgctggcg cctggcgcgg tcagcgaatc aacgccgcat aaagccggcg
    19201 ttatcgaaca tgtggtggtg attcagggtc ggctggacat gtgtactggt ggggtatggc
    19261 aaaccataga cgccggtaaa ggtttgcgtt ttgccggcga tacggcgcat acctatcgca
    19321 acagtagtga ccagacggtt cattttcact cgctgatcca ttacccacgt gattaagcgg
    19381 gaaaactatt tcgttagttt gcgcttctga ctacaatagc cgccatttcg ctgctattgg
    19441 ataagaaaga ctgtatgcgc cagcaacctc actatctcga attgttaagc ccggcccgtg
    19501 acgccgcaat tgctcgcgaa gcgattttgc atggcgcaga tgccgtctac atcggcggac
    19561 ccggttttgg cgcacgtcat aacgccagta acagtctgcg cgatatcgcc gatctggtcc
    19621 cgtttgctca ccgttacggc gccaggattt ttgtcacgct gaatactatc ctgcatgatg
    19681 atgagctgga gcccgcgcag cggttaatca ccgatttgta caataccggg gtggatgcgc
    19741 tgattgtgca ggatatgggc attctggaac tggatatccc gccgattgag cttcacgcca
    19801 gtacacagtg tgatattcgc agcgtggaaa aagcgaagtt tcttgccgat gtcggttttt
    19861 cacagattgt actggcgcgc gagcttaatt tgagtcagat agcggctatt catcaggcta
    19921 ctgacgccac gattgagttc ttcattcatg gcgcgctgtg tgtcgcttat tctggacagt
    19981 gttatatctc tcatgcgcaa accgggcgca gcgccaatcg gggcgactgt tcgcaggcct
    20041 gtcgcttacc gtatacgtta aaagacgatc aggggcgggt ggtctcttac gaaaaacatt
    20101 tgctatcgat gaaagataac gatcaaacgg ctaaccttgg cgcgttgatc gatgcaggcg
    20161 tacgttcctt caagattgaa gggcgctaca aagacatgag ctatgtcaaa aacatcaccg
    20221 cgcattatcg tcagatgctg gacgcgatta tcgagcaacg tggcgatctg gcgcgtgcat
    20281 cggttggtcg gaccgagcac ttttttgttc cctccacgga gaaaaccttc catcgcggca
    20341 gcaccgacta ttttgttaac gcgcgtaaag gcgatattgg cgcatttgat tcaccaaaat
    20401 ttattggctt gccggtaggc gaggtgctga atgtggcgaa ggattatctc gacgtagaag
    20461 cgacggagcc gttggcgaat ggcgatggtc tgaacgtgtt gattaagcgt gaagtggtgg
    20521 gttttcgcgc caatacggtg gagaaaaccg gtcataaccg ctaccgcgtt tggccaaatg
    20581 atatgcctgc cgacctgcat aaagtccgtc cgcatcatcc gttgaatcgt aatctggacc
    20641 ataactggca gcaagcgctg acaaaaacct ccagtgagcg ccgtgtggcg gttgatatca
    20701 tgctgggcgg ctggcaggaa cagcttattc tgacactgac cagtgaagac ggtgtctgca
    20761 tcacgcatac gcttgacggg gtatttgagg aagccaacaa ctctgaaaaa gcgttgaata
    20821 acctaacagc cggactggcg aagctgggac aaacgcttta ctacgcgcgt gatatgcagg
    20881 tgacattacc ggcggcgttg ttcgtgccaa atagcctgct caatcagttc cgtcgggagg
    20941 cgattgatat gcttgacgcg gcgcggctgg cccattatca acgaggtcgt cggaaacccg
    21001 tggcgcagcc tgcgcccgtc tatccgcaaa cgcatctcag ctttctcgct aatgtctaca
    21061 accacaaagc gcgggaattt tatcaccgtt acggcgtaca attgattgat gcggcctatg
    21121 aggcgcatca ggagaagggc gaggtaccgg tcatgatcac caaacactgc ctgcgttttg
    21181 cgttcaacct ttgtccaaag caggcgaaag gaaatattaa gagctggaaa gccacgccga
    21241 tgcagttggt gcatggtgat gaggtactga cgctaaaatt cgactgccgc ccttgcgaaa
    21301 tgcatgtcat tggcaaaatt aaaaaccaca tcttaaaaat gccccagccc ggcagcgttg
    21361 tcgcttcagt gagccctgaa gcgctgatga aaacgctgct gaagcgcagg ggcgtttaat
    21421 taacgaaaat agctctctgg tttgcgcgat ttctgccagt tgtggtgctc gcgcaagcct
    21481 tccgcggatt cttccgctgc cgcccgtaat tcatcgctgt cggcttcgtg tctaagctgg
    21541 tgccctcccg tcgcaaacca tacgaatgcg tggtcttgct gtttcgccag taactggcct
    21601 gaaaatagcg cacaggtcag taaaactact gataacgttt ttgtaagcat catgccacct
    21661 tccagttacg tcgtgaggct atgatgccaa taatttcttt gagttattat tcaacacttc
    21721 aaattagcga aaacggtttg tcaataagtg cgata
//
LOCUS       DAJVBX010000063        21539 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.063, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000063 DAJVBX010000000
VERSION     DAJVBX010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 21539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21539
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.063"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            257..646
                     /locus_tag="OPV72_002013"
     CDS             257..646
                     /locus_tag="OPV72_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000993573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914314.1"
                     /translation="MNAQARGARAARLYKRAKSKLISLDHFCVQKAREHKLPAWTGHL
                     PVTTLTGILFAAVIFGSLLFVSLGLFIFALILVTSWPGKRTNSADSWSDNSWGSSMRD
                     GSEGFGLYTGPENSHIPTSRIDNEDDL"
     gene            complement(682..2187)
                     /locus_tag="OPV72_002014"
     CDS             complement(682..2187)
                     /locus_tag="OPV72_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraG N-terminal
                     domain-containing protein"
                     /protein_id="HCR9914315.1"
                     /translation="MTTSSYLEYILTILGWVVNNGLWDVLTGTGLFALPLGFKIIGIW
                     IKTREEGDDEGNKGILSARRMEHAIYGAFIVIIACCVPTQTVSLTTLTFDTTRAKQCG
                     FWTPVKPGDSGYGSVVSTMSGMTASAPVWWAFMHMISKGVTQAAVASLPCRPDLRQVR
                     FDVQHTQITNPALAQELQDFTSDCYAQAFALWKRQDAGRTTDIDVLRDIEWLGSKIFL
                     KDFYPQLHSKLPRSAFPWSQSRDDGYANTGQGGYPTCSEWWSQNKTGLKSRVLDTVNT
                     TTMTRMAAAFKGMVSKEEYTEALIRRLVSPTSLSVSQNGRTYAGYGGNADFTLDNAVN
                     RMASVLGTSVGALGAFPAFDAMRQALPMVQALLLMAMYVLIPLVLVFGTYEYKTVVTL
                     TFVTFGMHFLTFWWELARWLDSWLLEIMYGSDSHSRWNVAGFQNSADDLIMNFVMGTM
                     FLVLPAVWMGALSWAGVRIGGIVDTNLNKGVQPAGQHGGKVGDKIGSGIAK"
     gene            complement(2520..3950)
                     /locus_tag="OPV72_002015"
     CDS             complement(2520..3950)
                     /locus_tag="OPV72_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010989292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrating conjugative element protein"
                     /protein_id="HCR9914316.1"
                     /translation="MRSQSILSVCLMLGIVSSGPLSAALLDAPTLSGDGYGKSVNGAV
                     SDKLFYSIGGGSVISTPGTMYGMKRIGLDAGLSSDLMCGNFDIKTTVGNQLNGVTNGF
                     KDLMGDVITGATGAVSSMPAMILQRANPGLYEMITNGVLQAGLAFDKSKLNCESMANK
                     LADYTLGDKSSWTESAVREEYKEAVSASGGDALRAEEARTKASGKEGATWVGGKKAGG
                     KGQPAIQPTRDLAKAGYNMMNNLSVTSNSTVSAGSCKGSACQKFKNSEEAAAAVVKVL
                     GDRSIRTCKDATECGSGGIDNAQGTTIAGTGFAPMLEDTTKENLEQLVKLVNGTEAPT
                     QANLDKIKSGSLKVTRGVIDALKRDPDAGALVQRLAGELAMSDTIETGLAMRRMLTTG
                     QSEPNAADQPQAMAEADRRIEALDRELNSLKLEMELRREVAKNTALVVVAREENRSVT
                     NPQKESQTNADTRLSELETRKPGDSQ"
     gene            complement(3965..4933)
                     /locus_tag="OPV72_002016"
     CDS             complement(3965..4933)
                     /locus_tag="OPV72_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03756 family integrating conjugative element
                     protein"
                     /protein_id="HCR9914317.1"
                     /translation="MKSLRLKRALLSVMLITGGMEVQAALNTASIVASSISPSCISWR
                     ISGICYWLMCTPFGCTVKTSIKVHHFIPEAVVSTYQASGGNPWTEMSLVSQTAGGVEN
                     AVTGALSGLAAGGGNQEQKFPGTRKSNVRFKYADAIGHPSTSIIGGQIPGYSCNSAAT
                     PLVPYFLSTLDTLAWRTGVPESVYPEALIPGRREIGSTSAQNIWGNLYPRSGFVTQQD
                     DYKSGAIVAQRVADIITRTNQIHVYKPLTGNPSAGYWPPEPVKENTGTQNHKWQQLSP
                     TLSMSCSVFPDTGKIAENGNYAWTLWQPYSCCKRRGQTFLYSTDIN"
     gene            complement(4930..5322)
                     /locus_tag="OPV72_002017"
     CDS             complement(4930..5322)
                     /locus_tag="OPV72_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03757 family integrating conjugative element
                     protein"
                     /protein_id="HCR9914318.1"
                     /translation="MKRILSSLILISSFSASAQIVVYTDQGHPPVGVTPAIRVVYLDA
                     SERWLQQQFGELSSDPEQAVRQAHSLLNSPDWKRRQKALIEHYRGMIEAWQLGLLKYP
                     AVVFDNRDVVYGTVDISRAVALRRGENQ"
     gene            complement(5477..5863)
                     /locus_tag="OPV72_002018"
     CDS             complement(5477..5863)
                     /locus_tag="OPV72_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914319.1"
                     /translation="MSLLKHEQWLILGEDESHRIPPDALLGLPPQGKAWIRKEHDEDM
                     SRLTSHIQGALGNTYRGVCHPQRIGHRACLAIHLENLRGKKLDILITVSGKTALPAEE
                     SYVNPRWYIDVADAADALYLALWLIR"
     gene            complement(6018..8823)
                     /locus_tag="OPV72_002019"
                     /pseudo
     CDS             complement(6018..8823)
                     /locus_tag="OPV72_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253395.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugative transfer ATPase"
     gene            complement(8823..9272)
                     /locus_tag="OPV72_002020"
     CDS             complement(8823..9272)
                     /locus_tag="OPV72_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03751 family conjugal transfer lipoprotein"
                     /protein_id="HCR9914320.1"
                     /translation="MVLTDNQKITSRTVKITPVLFFIAGMFSVALGGCSSSKDELLPP
                     GDSSMMELWQGNAPTSHAVVKGRETLRRSLSSQETLASGRIDESYSRTQENELSQIFP
                     RLPNPDMVMYIFPHLANGNTPVPGYSTVFPFYAQTQYALPGERTEAL"
     gene            complement(9259..10737)
                     /locus_tag="OPV72_002021"
     CDS             complement(9259..10737)
                     /locus_tag="OPV72_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03752 family integrating conjugative element
                     protein"
                     /protein_id="HCR9914321.1"
                     /translation="MQIKANGLMKVLLPVLIVVVCFIGVKACGLKDTTEPEPAKTTNA
                     LTELSQDDLKALGIEGDTSADTLRTLIGALRDVRARQAVLDEQNKALISENNKLKGEN
                     SSVGLQISNAVNAAKQETNEALEKQKTFLLEKLNDLTGTLKSQGQNTDMVSTGSSSGT
                     DFPVGLGLDPENASSATQGEVIWISPQDAKKTEGQSQSDNDKFTFPTSFLDDNPVSRQ
                     RAEYDRVVKNKQELDGNGAESDTRPVYTLPENSTLVGSKAMTALIGRIPINDKVTDPY
                     PFKVLIGKDNLTANGIELPDVEGAIVSGTATGDMVLSCVRGTIHSITFVFSDGRIRTL
                     PRPVANTQGNNNDNAGDRGSIGWISDNNGIPCISGERKSNASTYLPTVALLGMGSSAG
                     DALTQNQYTTQNNVNGGVTSALTGNAGQAVLGQTLGGGFKEVTDWVKQRYGQTFDAVY
                     VPPGANVAIHITRQLAVDYEDHGRKVRYDFSLPGTGGHYGLD"
     gene            complement(10727..11626)
                     /locus_tag="OPV72_002022"
     CDS             complement(10727..11626)
                     /locus_tag="OPV72_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001240640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03749 family integrating conjugative element
                     protein"
                     /protein_id="HCR9914322.1"
                     /translation="MAMFKVLNFKCKWWPIILLLWFSSAQAVELMKWERIPLLIPLSV
                     NHERIVFVDRNVRVGFPAMLKGKLRVQSSGGTVYLQASEPFEQTRLQLQDVESGEIIL
                     LDIAAKNDNKALEPVRLVYSGEVLSVSEKGMETGSSLPVASLDTEDKNQTVRKTPVYS
                     APLPVVLTRYAAQSLYAPLRTVEAVPGIHPVNLRLPSRLTTLYPSENVVVSPIGAWGI
                     QELNVVALKIRNRSSSKVILDARTLSGSFVSATFQHRWLGAAGTPEDTTTLYLVIRGR
                     PENAFIAEPAVLPAVKKGEQHAN"
     gene            complement(11626..12279)
                     /locus_tag="OPV72_002023"
     CDS             complement(11626..12279)
                     /locus_tag="OPV72_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016808259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03746 family integrating conjugative element
                     protein"
                     /protein_id="HCR9914323.1"
                     /translation="MSRFRHALKDRDQHILTLRLACGVLLLLLILVITGWMRAPSDLT
                     IHNPPDLRSGSTRKWWEVPPSTVYSFAFYIFQQINAWPKDGEKDYPMKIAQLSPYLTP
                     SCQDFLNKDAELRSQKGELLDRVRVVYEIPKRGYKPESVIIESDDSWEVSLDLVVDEY
                     YHTELVKRALARYPLHIVRWEGDPERNAFGLALDCYKGVPQRLEAAVVPEPEKKGMF"
     gene            complement(12276..12650)
                     /locus_tag="OPV72_002024"
     CDS             complement(12276..12650)
                     /locus_tag="OPV72_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03750 family conjugal transfer protein"
                     /protein_id="HCR9914324.1"
                     /translation="MKTIEFLPDRLNAETVVFRGFTTPELGYAALIGAVSGLILSLIM
                     MLVTGIGWPIIPTCTLITPLIFIFIGGRFLVRFKRNKPNFYLYLRIQKILSHIGIGSK
                     VLVRHDRRWSLRRSKPVRKGGI"
     gene            complement(12660..13022)
                     /locus_tag="OPV72_002025"
     CDS             complement(12660..13022)
                     /locus_tag="OPV72_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000949576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03745 family integrating conjugative element
                     membrane protein"
                     /protein_id="HCR9914325.1"
                     /translation="MLSKSKHGLRVPLPCLLILLLLVASFSSHAGLPTVNIPGGGGGG
                     DMMQTIKLLFSGFLVLMGLIICAVGFYMVSGAILATFSEIRSGKAEWGKFVAIVVVGI
                     AILVVIVWLCTEAAKILN"
     gene            complement(13052..13291)
                     /locus_tag="OPV72_002026"
     CDS             complement(13052..13291)
                     /locus_tag="OPV72_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001251281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03758 family integrating conjugative element
                     protein"
                     /protein_id="HCR9914326.1"
                     /translation="MAMNSEQANAFKAGSGIDPTVLNKFVLGFVLSVLFLWFAWSVLV
                     VFRGWRAGKVTEQNALHFFISTAILVVFSVWMFAS"
     gene            complement(13291..13545)
                     /locus_tag="OPV72_002027"
     CDS             complement(13291..13545)
                     /locus_tag="OPV72_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015701164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914327.1"
                     /translation="MVSAAEKDELALALRQLDQVQSALERAKIVAVQDNSDGRFFFDY
                     ERATRDLKTMKQGIETYLEPSRAQPRDKGSLVGQYRKEQP"
     gene            complement(13782..14540)
                     /locus_tag="OPV72_002028"
     CDS             complement(13782..14540)
                     /locus_tag="OPV72_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010989289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03747 family integrating conjugative element
                     membrane protein"
                     /protein_id="HCR9914328.1"
                     /translation="MSTEKNSSQSSPPPRKPPGLLTLVLWIWPVRLLAFLLVSWMAGV
                     FIEWAGMFFFWSDQGALHSQSVMNKELGYLSADFTQSLIFSSPSVTTMGWISSAYQWA
                     FVDSGLLTWIQKEQRETLSSSDSVVFFLGQVQAWLLSVLSDYLLALVYVTVVFAVRVL
                     ILVLSIPLFVLVIIVAVIDGLCRRDLRRYGAGYESSFLYHHAKRFVKPAVYLPCLLYL
                     SWPASIYPNLLLLPGALLLGLAVTVVTSTFKKYL"
     gene            complement(14537..16627)
                     /gene="traD"
                     /locus_tag="OPV72_002029"
     CDS             complement(14537..16627)
                     /gene="traD"
                     /locus_tag="OPV72_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system coupling
                     protein TraD"
                     /protein_id="HCR9914329.1"
                     /translation="MSNRYVMEALLRPAVELYSAAAGGAATFVLVVAPWSMALAPQVS
                     YVTAAGFAIFTTIRTRQGLRILRYRRNIRRLPRYQMSSESIPVSRHFLFLGKGFMWEQ
                     KHTQRLLETKRPEVAPFLKPSVFYSLARQFERRYEYTFPGLCSLTRRDSFFNPVRPLP
                     PVGGNSAIHGVEMEEDNVLMSLTERVGHLLVLGTTRVGKTRLAELLITQDIRRGNVTI
                     VFDPKGDADLLKRMWAETRRAGRSDEFYIFHLGWPDISARYNAVGRFGRVSEVASRVA
                     GQLGGEGNNAAFKEFAWRFVNIIARALVVLGLRPDYSLILRYVTNIAELYETYAEKLL
                     TQQAPELWLMVQNQMGILTEDDLPRTMQGQVNAIRVMAIEVALSSEQGKKIYDPVLDG
                     LRSAVRYDRTYFDKIVASLLPLLEKLTTGKTAALLSPDYSDMNDPRPLIDWQEIIRKG
                     GVVYVGLDALSDSEVASAVGNSMFADLVSTAGYIYKFGLSDDMPEGSSQRLPISLHCD
                     EFNELMGEEFIPMINKGGGAGIEVTAYTQTWSDIEAKIGNAAKAAQVTGNFNNMIMLR
                     VREKTTAELLTTQLPEVEIYTKTLVSGVTDISNPDQGSDFTSNVQDRVSSTRVPLLSP
                     AEVMNLPKGQAFALLEGGRLWKIRMPLPASVDDEMMPVNLQSIVTTMRKHYRTGDTWW
                     SGSVLPGDNLVDAL"
     gene            complement(16647..17216)
                     /locus_tag="OPV72_002030"
     CDS             complement(16647..17216)
                     /locus_tag="OPV72_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000626967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HCR9914330.1"
                     /translation="MITAILLLLFCLLIPAIWRKKMPSARDRRHRRYRQNAERVLCRL
                     TALDSDGARLKYLRKINPYVFEELLLLAFERQGLLVVRNQTYSSDGGLDGQVFIDGKR
                     WLIQAKRYRRTISPQHIREFGELITREQCCGFFIHTGRTGSKSVNYLQCWRTIQLISG
                     QRLLDLLAGRQCWYHRPVTKSVAGQPVVT"
     gene            complement(17226..17726)
                     /locus_tag="OPV72_002031"
     CDS             complement(17226..17726)
                     /locus_tag="OPV72_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrating conjugative element protein"
                     /protein_id="HCR9914331.1"
                     /translation="MVSILLTTSSMAALNVIADLGGEPTAPLFDAINNKNNEFTPPRS
                     LNATGASVTAAPADVSDMLPVTTPEMRAGKVEARELNLNGMTPVFLVGDDSLSREWLT
                     MRRDELKRLHATGLVVNVSDKDALSELQQIIPDVILLPASASEIARRLHLNHYPVLIT
                     ATGLAQ"
     gene            complement(17762..18448)
                     /locus_tag="OPV72_002032"
     CDS             complement(17762..18448)
                     /locus_tag="OPV72_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HCR9914332.1"
                     /translation="MANRSILTAARYSVPVLILLIGGVGSAAAVEKGRGLQTIPPGYH
                     LVATEVGVPAEALYSVSLAETSRKLPHGERPWPWTLNVAGKGYRYNSRQEAYDAMLSF
                     MRRYPLKRIDVGIAQVNLGWNGTYFSSYYEALDPYTNLRVAARILKSCYDNNPGSWIQ
                     AAGCYHHPAGGKPARIYKSIVKRKLATLDLNAPVTYSELQIAQISPSQRHFSHYNREL
                     QWVEPRESRQ"
     gene            complement(18427..19167)
                     /locus_tag="OPV72_002033"
     CDS             complement(18427..19167)
                     /locus_tag="OPV72_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001768408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03759 family integrating conjugative element
                     protein"
                     /protein_id="HCR9914333.1"
                     /translation="MKPMKSTLNCLRQWTASVMLAVIVSLPALASVSTGRSVSAPQQQ
                     NTTTEGRTQTSGTAWGLSEKEWQQYQQVLKGPRAFQSPGIDPLMALGLEAGSASERRR
                     FAEMWVKEEYARGEKELAFQREVDAAWKRLYPNTLSVNMGNASGIAHDTQGRLALFVK
                     RNCVPCDARVSAVLADNRPVDIYLVDSGGSDDTIRQWALAHHIPVDKVRSRQITLNHD
                     NGNWLKYGQGYMPVMLQQGVSGWQIAAF"
     gene            complement(19186..20100)
                     /locus_tag="OPV72_002034"
     CDS             complement(19186..20100)
                     /locus_tag="OPV72_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000214158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914334.1"
                     /translation="MTTTTASSVDIPSDNDLPLSAHLTEPAEPAIDTSDITVTPDTSA
                     QSAAYRLGGKRSRLWHPSSDRRSLIFKVSSVLVYCLLLGAVLFLWLTVRQQQIQLTTL
                     DAAFRSGQLQTLPDRMQAIEDRQQQFVPKLQGEKWQLRLSEQELRLTAFEQQLSSLVT
                     EVKETQAATARAVAREDETGMKLDAVHKALTEQTSRIDTLASWKDTWSKRTVATATKA
                     TPSPGGGQSAAKKSSKPRVIKPPFTLVSIERRGGQAYAVILPAGNSGWTQLRMVSPGE
                     SLSGWVLVNISGNQAEFQVNGQVQRLTL"
     gene            complement(20057..20419)
                     /locus_tag="OPV72_002035"
     CDS             complement(20057..20419)
                     /locus_tag="OPV72_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914335.1"
                     /translation="MQAWLNELAGAYRRVEVMTYREIITALPALPADGEWWRRSLRGV
                     GRQRAPSTLYLHIAHIFKRLPVCVPDANLDPLFSLLSFDLSVVSAELFLHSHGENRFP
                     EDLYHDDNDGIFCRYSVR"
     gene            complement(20607..21482)
                     /locus_tag="OPV72_002036"
     CDS             complement(20607..21482)
                     /locus_tag="OPV72_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000994659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914336.1"
                     /translation="MNATYNALIALMRSGEIPLETGASVSAPSAQFSVRIRPETRVFL
                     DRCAEHLGISRAAMFGMCIDGIVAEARESIADRTSTLYERFCLLLDAHGLNVIEQAQL
                     LASWGIRASVLASQDRTLDLLNKPLLQQLSTWFDVDVNWLLGNSSYPVDMADGQRDWA
                     VQTPSLLCRLQSIQSVDPVELIFFWQQGRKPQSVGLCLRYRPLISGEPIGLLRVYQAL
                     DWQDEQVQQAYNQLRRITSITLGGYTKDKVEKYPPIRLRYFTFSARQMQALDNGAVIP
                     AMIFDKPKGEFPSIS"
BASE COUNT         5658 a         5808 c         4779 g         5294 t
ORIGIN      
        1 aataaacatt cggctttaaa aagaaaaatt taataattta ctaaacaaaa ctaaatctcc
       61 tggttggtgg tgctaatgac tcggtaatct gtaaacaccc cactcaggag ttacaaattt
      121 atgtccattc tttcttcggc caacaattgt taaaccaatc aaaaacccca cattgatcgt
      181 cacaatgaac ttgatgtttt cttcgctagt tgagatgctt aaattatgaa gatacacaca
      241 ttcaggagca cagcaaatga acgcacaagc acgcggtgcc cgggccgcaa ggctttataa
      301 aagggctaag tcaaagctga tttcactcga ccatttctgt gttcaaaaag ccagagagca
      361 taagctgccc gcctggactg gtcatctccc ggtgacaacc ctgacaggga ttctttttgc
      421 tgcagtgatt tttggctcac tgttatttgt gagcttaggc ttatttatat ttgcacttat
      481 tctggttaca tcgtggcctg gaaaaagaac aaactctgcg gactcgtgga gcgataactc
      541 ttggggaagc tcaatgagag atggaagcga gggatttggt ctatacactg gcccagaaaa
      601 tagccatata ccaacaagta ggatagataa tgaggatgac ctatgaaagc actgtaatat
      661 ttacagtgct ttcacgattt cttatttagc tattcccgag ccaattttat caccaacttt
      721 gccaccatgc tgtccagctg gctgcactcc cttatttaag ttagtgtcaa caatgccgcc
      781 aattctaacc ccagcccagg aaagcgcccc catccacact gccggcaaca ccaggaacat
      841 cgtccccata acaaagttca tgatcaggtc atctgcgcta ttctgaaaac cggccacatt
      901 ccatcggcta tggctgtccg aaccatacat gatctccaga agccagctat ccagccagcg
      961 cgccagctcc caccagaacg taagaaaatg catcccaaac gtcacaaaag tgagagtgac
     1021 tactgtctta tattcatacg tcccgaatac cagcaccagg gggattagta catacatggc
     1081 catcaataaa agtgcctgaa ccatcggtaa cgcctggcgc atggcatcaa atgcggggaa
     1141 cgccccaagg gcacccacac tggtccccag cactgaagcc atgcgattta cagcattatc
     1201 taacgtaaaa tcggcattac cgccataacc tgcataagta cgtccattct gtgacacaga
     1261 gagacttgtc ggactgacca gacgtcgaat tagcgcttcc gtgtattcct ctttgctgac
     1321 cattccctta aatgctgccg ccatgcgtgt catcgtggtg gtatttaccg tatccagcac
     1381 acgggatttc aggcctgtct tgttctgaga ccaccactcg ctacacgttg gatacccccc
     1441 ctgcccggta tttgcgtacc cgtcatcgcg gctttgcgac caggggaacg ctgacctggg
     1501 caacttcgaa tgcagctgcg ggtaaaaatc cttcaaaaat attttcgacc ccagccattc
     1561 aatatccctg agtacatcaa tatccgtagt tctccccgca tcctgccgtt tccataacgc
     1621 aaaagcctgt gcataacagt cactggtaaa atcctgcaat tcctgagcca gagcaggatt
     1681 ggtgatctgc gtatgctgaa cgtcaaaacg cacctgccgc aggtctggcc ggcagggtaa
     1741 acttgccaca gccgcctgag tgacgccttt ggaaatcata tgcataaatg cccaccacac
     1801 cggcgcagat gcagtcatac cactcattgt tgaaaccaca ctaccgtagc ctgaatcccc
     1861 gggcttgacc ggtgtccaga aaccacactg tttcgcacgg gttgtatcaa acgtcagcgt
     1921 tgtcagtgac actgtctgag tggggacaca gcaggcgata ataacgataa atgccccgta
     1981 aatagcatgt tccatccgtc gggccgacag gataccttta ttaccctcat catccccttc
     2041 ttcccgtgtt ttgatccaga taccaatgat tttaaagccc agtggtaatg caaaaagtcc
     2101 cgtgcctgtc agaacatccc acaaaccgtt attaacaacc cagcccagaa tcgtcaggat
     2161 gtactcaaga tagctcgatg tcgtcatctt ctacctcaac actgaatatt cgcaaatcgc
     2221 gacgaaacca acagaaacga cagcaatccg cagaagactc tgacgcagag cctgagaaga
     2281 gccatgggag tgataacaac gccatatccc ccaaccagtc acgctgtaaa gcatcagccg
     2341 ccacagaagc cacaacaacc aggtttcctt catccagatc cggaactggg ctatttcaga
     2401 ctgataacga aaccctaaat cagccagtgc aagggacagg cacgtaagca taaccagcat
     2461 gaacacaagc gtcagaataa atctcagaaa tgaagttgtt ttgattaaga tcctcagtgt
     2521 cattggctgt cccctggttt acgcgtttca agctcactca gccgggtatc agcattagtc
     2581 tgcgattctt tttgaggatt ggtgaccgaa cgattttctt cgcgcgcaac cacaaccagc
     2641 gcggtatttt ttgccacttc ccgacgcagt tccatctcca gcttaagaga gttaagctca
     2701 cgatcgagag cttcaatacg gcgatcggct tcagccattg cctgaggctg atcagctgca
     2761 ttgggttcag actggccagt cgttaacatg cgacgcatcg ccagaccggt ttcaatcgtg
     2821 tcggacatgg ccagttcgcc agccagtctc tgaaccaacg caccggcatc aggatcgcgt
     2881 ttcagggcat cgatgacacc acgcgttacc ttaaggctgc cacttttaat tttatccaga
     2941 ttggcctgag tcggagcctc agtaccattt acaagcttta ccagctgttc cagattctct
     3001 ttggttgtat cctcaagcat gggagcaaaa ccggtaccgg caattgtcgt gccctgggca
     3061 ttatcaatcc cgccgcttcc gcattctgtg gcatctttac aggtgcgaat actccgatcg
     3121 cccagaactt ttacgaccgc tgctgcagct tcttcagagt ttttaaattt ctggcatgct
     3181 gaccccttgc aactaccggc ggataccgtg ctgttgctgg taacgctcag gttattcatc
     3241 atgttgtatc ctgctttagc cagatcacgc gttggctgaa tggcaggctg gcctttccct
     3301 ccggctttct tcccgcctac ccaggtagcg ccctccttac ctgaagcttt ggttctggcc
     3361 tcttctgccc gcagcgcatc cccgccactg gcactgaccg cctccttgta ctcttccctc
     3421 acagctgatt ctgtccagct gctcttgtca cccaaagtgt aatcagccag cttgttggcc
     3481 atgctttcac aattcagttt cgatttgtca aaagccagac ctgcctgaag tacaccattg
     3541 gtgatcattt catacaaacc cggatttgct cgctgaagga tcatcgccgg catacttgag
     3601 accgccccgg tcgcaccggt gatcacatcc cccatcaaat ctttgaaacc attcgtgacg
     3661 ccattaagct ggtttccgac agtagtcttt atatcaaagt tgccacacat caaatcactg
     3721 ctcagtccgg catccagccc gatacgtttc attccgtaca tcgtcccggg agtggaaatc
     3781 accgaaccac caccaatgct gtaaaacagc ttgtcactaa ccgcgccatt tactgacttt
     3841 ccatatccat caccactcaa cgtgggggca tccagtaatg cagcacttaa cggtcccgaa
     3901 ctgacgatac ccagcatgag acagacggat aaaatggatt gagatctcat tttcgatact
     3961 ccacttaatt tatgtcggtg ctatagagaa atgtttgccc acggcgttta cagcagctat
     4021 atggctgcca gagtgtccag gcgtaattac cgttttccgc aatttttcct gtatccggga
     4081 atacgctgca tgacatagag agcgttggtg ataactgctg ccatttatga ttttgcgtgc
     4141 cggtattctc tttaacaggt tcgggaggcc agtaaccggc agacgggttt ccggtgaggg
     4201 gcttatagac gtggatctgg ttagttcggg tgataatgtc agctacacgc tgcgcaacga
     4261 ttgccccgga tttgtagtca tcctgctgag taacaaagcc gcttcgggga tagagatttc
     4321 cccatatatt ttgtgccgat gtggagccga tttcgcgtct gccaggaatg agtgcctcag
     4381 gataaaccga ttcaggaaca ccagtacgcc aggcaagcgt atcaagcgtg ctaagaaaat
     4441 agggtaccag tggtgtggcg gcgctgttgc atgagtaacc ggggatttgg ccgccaataa
     4501 tcgatgttga aggatggcca atggcatctg catatttaaa tcgcacatta ctcttacggg
     4561 tacccgggaa tttctgttcc tggtttccgc caccggcagc aagcccggat aacgcccccg
     4621 ttacagcatt ctctacccct ccggccgtct gactcactaa tgacatttcg gtccacggat
     4681 ttccaccaga cgcctgataa gtcgaaacaa cagcttccgg aataaagtga tgcactttta
     4741 tcgaggtttt tactgtacaa ccgaaagggg tacacatcag ccagtagcag ataccgctga
     4801 ttctccagct gatacacgac ggagaaatac tgctggccac aatcgaggca gtgttcaacg
     4861 cagcctgaac ctccatgccg ccggtgataa gcatgactga cagtaacgct cgcttcagac
     4921 gaagagattt cattgattct ctcccctgcg cagcgccact gcccgggata tatcaacagt
     4981 cccgtaaacc acgtcacggt tgtcaaaaac caccgccgga tatttcagta aaccaagctg
     5041 ccatgcttca atcattcccc tgtaatgttc gataagcgct ttttgccgtc tcttccagtc
     5101 aggagaattc agcagagaat gagcctgtct gacagcctgt tcaggatcag aagaaagctc
     5161 tccaaattgt tgctgcagcc agcgttcgct ggcatcgaga taaacaaccc ggatagccgg
     5221 tgttacaccg accggaggat gcccctggtc ggtgtaaaca acgatttgcg cacttgcaga
     5281 aaaggagctg attaatatca gcgaagagag gattcgtttc atgccacgct cctgacgata
     5341 actatccgga tagcgtgcga aaaacgcaga ggtaatgcag taataaactc tgttttgctt
     5401 tttaataatt ccccgcttca gaatatgtgg aagcggaata tgaaacgccg gcttttacgc
     5461 cggcgagtgt acctgtctac ctgataagcc acagcgccag ataaagggca tctgcggcat
     5521 cggcaacatc gatgtaccat cggggattaa cgtaactttc ctccgcaggt aatgctgtct
     5581 ttccgcttac cgtaattaat atatccagct tttttccgcg taaattctca agatggattg
     5641 ccaggcaggc acgatgcccg atacgctgtg gatgacaaac cccacgataa gtattgccaa
     5701 gagctccctg aatatgagaa gtcagacgac tcatatcctc atcatgttcc ttgcggatcc
     5761 acgctttacc ctgcggaggc aaacccagca gcgcatcagg cggaatacga tgcgattcat
     5821 cttcaccgag aattaaccat tgctcatgct ttaacaggct cataatcccc ccattgaaat
     5881 accatcattg agcaaaagag atccttcacg tccagcctcc ccggacaacc actctgatga
     5941 cataacaatg actcctctga tattggtaaa actggtcaca gggcttggcc attgcccgtg
     6001 gctcaggaat tgttttttca ggccgctttt tgtggacaaa aaccccgtgc ctcatccagc
     6061 ctgcgggcca cccggatcgc tgcctcaagc tcactgcact gatactctcg catcagccgc
     6121 tgacgttccg ctttttcctc tttttcagtc atccccaggg cgagatacag actgggaggc
     6181 acaacccgga acagtgcctc aacctgcttt gataaaacga cgccctcggt ataacagttt
     6241 ttgagcttac tggctgatcg caaaataact ttttgctcct cgctgagggt tttgaaacgg
     6301 gcaatctgct ccacctcatc gggaggcata accaggcaca accaccattc agccatgttc
     6361 agcattttct gcgcaatatc aggaaaatcc tcgaggttct gtgtcgccag ccacagccat
     6421 gcccccagtt ttcgccacat tttcacaacc ttggtcatat agggcgacaa caaaggattc
     6481 gtcgtggaaa tatgggcttc atcaaatacg gccacaatat cccgggctgt tccctggtca
     6541 cgttcggcga tattgttaat cgtgttaatt aaagagacca tcgccagcgc catttgtgca
     6601 ccatagcctt cacgtgccag atgacctaaa tcgatcagtg tgacatcagc ctctggccat
     6661 ggtgttcccg gacggttgaa taactctccc tcaaatccct gagtgaacat ggccatggct
     6721 tctgccatct cagcagcacg atcgcgacgg gactgattcc gcataggctc gccatttgca
     6781 ccaatggaat tatcacgtga gatattccac agggcagcct gtaaatcctc agccagcatc
     6841 tgatgtccgt cctgatatgt tttctccgcc gccatcatga tagcttcacg aataagaccg
     6901 cggtcagccc gggtaagacg ttcctcctcc cgcttctcgc caccggtgat catcatccgg
     6961 gctgcaattt ccatttcgcc aagaatgtca cgctcttcac tttcatcttc tgcgctgtcg
     7021 gtattggctg gctccagctc aggtagagct tcctcagaaa ccacgttttt ctttggatct
     7081 actcgcatta aggaatgagc atcagcaaac atcggtaaag aaataccgca gccaggtttg
     7141 atactcagta catttacgct cagtcccagc ccccggaaat actccgccag caaaccaaaa
     7201 ctgttgccgg cttcggcaat aaagaggcgt ggacgatgaa cggccattaa ctgtgataac
     7261 gcactacata aggtggctga tttacccgcc ccggtcggac caaaaagcaa caggtgagca
     7321 ttctgcgttc tgtccagact atttaaggga tcaaaagaca acagttctcc gccacggtta
     7381 aaaaaactaa acccggggga agcaatccag ccagatgctg aacccaggtc aggcgggtat
     7441 accagttttt tttatccagt tgcgggttaa aacacatagg aagcgctcgc aaatagtcat
     7501 tcaggggcgc cacttcgtat tcaggtttcg tgggctggag ccccgcagtc agcaatgtag
     7561 cggtaagttg ctgtattttt ttattcagct cactgacatc aggtgcacgc atcaaaaaag
     7621 ttatcgatgc acgataaagt ttgtgacgca tgcccagcaa actcttcacc tgctccacat
     7681 cactacgggt ccgcctggat tccgtgttct gccctattgc atttttaccc agcgtgtcaa
     7741 acccggcttc cagcgtgtcc tgagcctgcg ccacaatagt gagcgatacc attgtgccct
     7801 caggcaataa atccatcaga gtattaatat tgtcgccacg cttaacctcc cccgtcagat
     7861 gaccgggtcc cggagggcga cgtaatgttt caacaggaac ggcacgatgc gccacattat
     7921 caaaccacca cacaccattt cgggtatcag aacgtggagg gttaaaccac aacgtctcag
     7981 tgaaatcatt gccaagaggc aatgaatcag gtgcatcatc ataataacga gcctcccggt
     8041 aaagcgtatc tttgtctatc cagtcgggct caggattgaa gtgacgtaac aaccatcgat
     8101 gtatctgctc gccattctgt cggacactca gaacgccggc tgcagataag gctgaagtca
     8161 ggcgctcaca aacctggttg agagcggcaa ccggcgaatc atctttgtaa ttcgctggca
     8221 ggtatcgata taccaccatc ctgacggaac gattttgtcc ccgccaggga accccggtga
     8281 caagtgaatc agtgaacaaa ccttccggcc gggtgatatt tcgcagatgc tgttctgttt
     8341 cagccagcca ggccttcgta aatgccgtcc tctgagcatg cggtttgatg taactggcta
     8401 accgattcat ataggcactg aagtcagttt catcctgaca aaaaactgta ctacccatgg
     8461 gttagaatca aactcttcaa ggctgtcctg aagtgcatct tcaaccgaat cccttatttc
     8521 ttccagacgg gcagctgtgc gcccctctga tgccactggc gatatactgt ataccgcacc
     8581 gacagactgg ccatcgtcaa gcagcagaca ttgctcgcga ctcaggtact cggcccaggg
     8641 caaaaaatca ataatggacg gacgggtttc gtataaacgg gattcatcag cgtgactcat
     8701 catgcccggg cgtttcagtg ggtcacggcc atgaacagca aagtcacttt ccggtaactc
     8761 gtcaggctcc cggggagaag atgacttcag cctgtttttg ttaaacaaag aaaaactgac
     8821 catcacagtg cctccgtccg ttcaccagga agcgcatact gggtttgagc ataaaaagga
     8881 aagacagtgc tgtagccagg aacaggcgta tttccattag ccaagtgcgg aaatatgtac
     8941 atcaccatat ccggattagg taaccggggg aaaatctggc tcagctcatt ctcctgagta
     9001 cggctgtagc tttcatcaat acgccctgaa gccagtgttt cctgagacga aagactccgc
     9061 ctgagagtct cccgcccttt gacaacggcg tgagatgtcg gagcattccc ctgccagagc
     9121 tccatcattg aactgtctcc cggaggcaat aattcatctt tgctggatga gcatccacca
     9181 agcgcgacac tgaacatgcc cgctataaaa aataaaacgg gagttatttt cactgtacgt
     9241 gaagtgattt tctgattatc agtcaagacc ataatggcct cctgttccgg gcaagctgaa
     9301 gtcatatcga accttacgac catggtcttc ataatcaacg gccagttgac gagtaatatg
     9361 aatagcgaca tttgcaccag gtgggacata caccgcatca aacgtctgtc cgtaacgttg
     9421 tttaacccag tcggtaactt ctttaaatcc ccctcccagc gtctgcccca gtaccgcctg
     9481 ccccgcattg ccggttaagg ctgatgtcac cccaccattc acattgttct gagtggtata
     9541 ttgattttgt gttaacgcat cacctgcgga gcttcccatc cccagtaacg caaccgttgg
     9601 cagataagtt gaagcattag atttgcgctc accactgata cagggaattc cgttgttatc
     9661 tgatatccag ccaatgctgc ccctgtctcc ggcgttgtca ttattgttgc cctgagtgtt
     9721 tgctacgggt ctgggaagtg ttcttatacg tccatcggaa aaaacaaacg tgatcgaatg
     9781 tatcgttcct ctgacacacg aaagcaccat atcccctgta gcagtcccgg aaacaatagc
     9841 cccctcaaca tcgggcaatt cgataccgtt tgcagttagg ttatccttac cgatcaggac
     9901 tttaaatgga taaggatcgg tgactttgtc attaattggt atacgaccaa ttaatgccgt
     9961 catcgcctta ctgcctacca gggttgagtt ctcaggcaac gtataaacag gccgtgtatc
    10021 ggactctgca ccgtttccgt ccagttcctg cttgttttta acaacgcgat cgtactcagc
    10081 tcgctgacga ctgacggggt tatcatccag aaaagaggtg ggaaaggtga atttatcatt
    10141 atcactctgg ctttgaccct ctgtcttttt agcatcctga ggagatatcc agatcacctc
    10201 cccctgagtt gcagaggatg cattctctgg atccagtcca aggccaaccg ggaaatcggt
    10261 tcctgaagac gaacctgtcg acaccatgtc agtgttttgt ccctgggatt tcagtgttcc
    10321 ggtcaggtca ttgagcttct ccagtaggaa cgttttctgt ttttcaagag cctcgttcgt
    10381 ttcctgtttt gcggcattta cagcatttga tatctggagt cctaccgatg aattctcacc
    10441 cttgagctta ttattttcag aaatgagtgc cttattttgc tcatccagca cagcctggcg
    10501 ggcccggaca tcacgcaacg ctccaataag tgtacgtagc gtgtctgctg acgtatcccc
    10561 ctcaataccc agtgctttca aatcatcctg gctcaactca gtcaatgcat tagtggtttt
    10621 agcgggttca ggttcagtag tatcttttaa accacaggct ttaacgccaa taaaacaaac
    10681 caccacgatc aatactggaa gtaaaacctt catcaggcca ttggctttaa tttgcatgct
    10741 gttccccttt ttttactgcc ggcaatactg caggttcagc aataaaggca ttctcagggc
    10801 gccctctgat cacaagataa agagttgttg tatcttcagg cgtaccagcc gccccaagcc
    10861 aacgatgctg gaaagtcgca ctgacaaacg atcctgataa agtccgggca tcaagtatca
    10921 ctttggagga agaacgattc cggattttca gtgcaacaac attcagttcc tgaatacccc
    10981 atgcccctat tggcgaaaca actacattct cagacggata taaagttgtg agtctcgagg
    11041 gaaggcgtaa atttaccgga tgaattccgg gtacagcttc aacagtgcgt agaggggcat
    11101 acagactttg tgcagcataa cgagtcaaca ccactggcaa tggagcactg tacaccggcg
    11161 tttttctgac agtctgattt ttatcttctg tatccaaaga ggcgactggc aacgaagaac
    11221 ccgtttccat tcctttttcg ctcaccgata acacttctcc cgaataaacc aggcgaacag
    11281 gctcaagcgc cttattgtca tttttggcag caatatccag taatataatc tcgcccgatt
    11341 caacatcctg cagttgaagt cgggtctgtt caaaaggttc gctggcctgt aaataaaccg
    11401 taccaccgct gctttgaacc ctcagtttac ctttgagcat tgccggaaaa cctacacgaa
    11461 cgttgcggtc gacaaagaca attcgctcat ggttaacaga aagtggaata agcagaggga
    11521 tccgttccca tttcatcagc tccacagcct gtgctgatga aaaccataaa aggagaatta
    11581 tcggccacca tttacactta aaattaagga ctttaaacat cgccattaaa acatcccctt
    11641 tttctctggc tcagggacca ctgcagcttc aagtcgttgt gggacgcctt tatagcaatc
    11701 aagcgccaga ccaaaagcat tgcgctccgg atcaccttcc cagcggacaa tatgcagggg
    11761 gtatctggcc agtgcccgtt ttacaagttc tgtgtgatag tattcatcga ctaccaaatc
    11821 cagactgacc tcccaactgt catcgctctc aatgatgaca ctttcaggtt tgtaaccacg
    11881 tttggggatc tcataaacga cgcgaacgcg atcaagcaac tcaccttttt gactccgtag
    11941 ctcagcatcc ttattcaaaa aatcctggca tgatggcgta agataaggac tcaactgggc
    12001 aattttcatc ggatagtctt tttctccgtc cttcggccag gcattaattt gctgaaaaat
    12061 ataaaaggca aagctgtaga ccgtactcgg agggacctcc caccatttac gcgtactccc
    12121 gctgcgtaaa tctggcgggt tatgtattgt caggtcactg ggcgcccgca tccatcctgt
    12181 aataaccaga atcaataaga gaagcagaac tccacacgct aatctcaggg tcaaaatatg
    12241 ctgatcgcga tccttcagag catggcgaaa tcggctcata ttcccccctt gcgtacaggc
    12301 ttactcctgc gtaatgacca gcgtcgatca tgacggacca gaactttgct cccgatacca
    12361 atatggctca gtattttttg aatccggagg tagaggtaaa aattgggttt attacgttta
    12421 aaacgaacca gaaagcgtcc accgataaaa ataaatatca gtggagtgat aagagtacag
    12481 gttggaataa ttggccagcc gatccccgtt acaagcatca ttatcagaga caaaattaag
    12541 cctgacacgg caccaataag tgctgcatag cccagttctg gtgttgtaaa ccctctgaaa
    12601 actaccgttt cggcattcag cctgtccggt aaaaactcga ttgttttcat gaggccacct
    12661 caattcaaaa tcttcgcggc ttcagtacac aaccagacaa tgacaacgag aatggctata
    12721 ccgacaacga caatcgcaac aaatttaccc cattctgctt taccggagcg tatttctgag
    12781 aatgtcgcca gaatagcgcc ggaaaccata taaaatccga cagcacaaat gattagcccc
    12841 atcaggacga gaaacccaga aaacagaagc ttgatcgttt gcatcatgtc acccccaccg
    12901 cccccaccgg gaatattgac cgtaggtaat cctgcatgag aggagaagct cgccaccagt
    12961 aacagcagaa tcaaaagaca gggaagtggt actcttaacc catgtttact ctttgaaagc
    13021 atcatgtttt ccttttaacc aaacaaatta ttcagctggc gaacatccat actgaaaaca
    13081 caaccaaaat ggccgtactg ataaaaaaat ggagagcatt ttgctcagtg acttttcctg
    13141 cccgccatcc acgaaacaca actaataccg accaggcaaa ccacaaaaaa agaacgctca
    13201 gaacaaaacc cagaacaaac ttattaagta ccgtagggtc gatacctgac cctgctttaa
    13261 aagcgtttgc ctgttcagaa ttcatagcca tcagggctgc tccttcctgt attgtccaac
    13321 aagagaacct ttgtctcttg gctgtgcccg ggaaggctcc agataagttt caatcccctg
    13381 cttcatggtt ttcaaatcac gtgttgcccg ctcatagtcg aagaagaaac gcccgtcaga
    13441 attgtcctgt accgctacaa ttttcgcgcg ttcaagcgca gactggacct ggtccagctg
    13501 cctgagagcg agggccagtt catccttttc agctgcactg accatctctg gcagagagaa
    13561 caaactgagg acgagtaaaa acccttaaag gtctggaaga taattgacat ctttgcatta
    13621 ccacctctgt ttcatggagt acgtctgtca caacagagtg gcgaaatcag ggaggagatg
    13681 cagcaggaaa ctctttatgc ttttttgaaa tttatatcct cccggggggc tggtgccagc
    13741 cccccagaga agacaataag tcagcggttg accctggccg gtcacagata ttttttgaat
    13801 gtagatgtca ctacagtaac cgccagtccc agtaacaatg ccccgggcag aagtaacaga
    13861 tttggataaa tcgacgcagg ccatgacaag taaagtaagc aagggagata aacagccggt
    13921 ttaacaaacc gtttggcatg gtgatacaga aaactcgact cataacccgc cccgtaacgt
    13981 ctcaggtcac gacgacacaa cccgtctata acagcgacga tgataaccag aacaaataac
    14041 gggatggata aaacaagaat taataccctg acggcaaaaa cgacggtgac ataaaccagc
    14101 gcaagcagat aatcgcttaa cactgataat aaccaggcct gcacttgtcc cagaaaaaaa
    14161 acaacagagt cagaactgct taatgtctcc ctttgttctt tctgaatcca ggtgagtaat
    14221 ccactgtcca caaatgccca ttggtaagct gacgaaatcc agcccatcgt agttactgat
    14281 ggtgaagaaa aaataaggct ttgagtaaaa tctgctgata aatagccaag ttctttattc
    14341 ataacggact gggaatgcaa agctccctga tctgaccaga aaaaaaacat tcctgcccat
    14401 tcaataaaaa caccagccat ccaggatacc agcagaaaag ccaaaagcct gactggccag
    14461 atccacaaaa caagggtcag caaacctggt ggcttgcgcg gtggtggaga actttgagag
    14521 ctgttttttt ctgtactcat agcgcatcca ccagattatc tccggggagc acactccctg
    14581 accaccaggt gtctcccgtt cggtagtgtt tacgcattgt agtgacaata ctctgcaggt
    14641 ttaccggcat catttcatca tcaacggatg ccggcagcgg catacgaatc ttccataatc
    14701 gccctccttc cagcagtgca aaagcctgcc ctttaggtaa attcattact tctgcaggag
    14761 ataaaagagg aacacgtgta ctgcttactc tgtcctgaac gttggatgtg aaatcactcc
    14821 cctgatccgg attggatata tctgtcacac cggaaaccag tgtttttgta taaatttcaa
    14881 cttcaggtaa ttgcgttgtc agcaactcag ctgtcgtttt ctctctcaca cgaagcataa
    14941 tcatattatt gaaattgcct gtgacctggg cagctttagc tgcattacca attttggcct
    15001 caatatctga ccaggtctgg gtataggctg taacttcaat acctgcccca ccgcctttat
    15061 ttatcatcgg aatgaattct tctcccatta actcattgaa ttcatcacag tgaagactga
    15121 tgggtaaccg ctggctactc ccttcgggca tatcatcaga cagtccgaac ttataaatat
    15181 atccagctgt tgaaaccaga tcggcaaaca tactgttacc taccgcagaa gcaacttcag
    15241 aatctgaaag agcatcaaga ccgacgtaaa caacaccgcc tttccgtata atttcctgcc
    15301 agtctattaa tgggcgcgga tcattcatat cactgtagtc aggagataat agtgccgcag
    15361 ttttgcctgt ggtcagtttt tccagaagag gtaacaatga agcgactatt ttatcgaaat
    15421 atgttcgatc ataacgtaca gcgctacgca acccatccag tacgggatcg tatatttttt
    15481 tgccctgctc actggataat gccacttcaa tggccataac ccgaatagca ttaacctgtc
    15541 cctgcatcgt acgtggtaaa tcatcctcag tcaggatccc catctggttt tgaaccatca
    15601 gccacaactc cggagcctgt tgagtcagta acttctcggc ataggtctca taaagctctg
    15661 caatatttgt tacgtaccgg aggataagcg aataatcagg tcgcaaacca agaacgacaa
    15721 gagcacgagc gatgatattg acaaagcgcc atgcaaactc tttaaacgca gcgttatttc
    15781 cttctccccc aagctgcccg gcaacacgtg aggccacttc agatacgcgt ccaaaacggc
    15841 cgactgcatt ataacgggca ctgatatctg gccagccaag atgaaagata taaaactcgt
    15901 cgctacgccc agctcgcctc gtctcagccc acattcgttt caacagatca gcatcacctt
    15961 tggggtcaaa aacgatagtg acatttcctc tgcgaatatc ctgcgtaatt aacagttctg
    16021 ccagacgggt cttaccaact cgtgtcgttc ctaatacaag aagatgtcca acgcgctcgg
    16081 taagactcat caaaacatta tcttcctcca tctcgacacc atgtatcgcc gaattaccac
    16141 caacaggggg taatgggcgt accggattaa aaaatgaatc tcgtcttgtc aggctacata
    16201 acccagggaa tgtatactca taccgtcgtt caaactgacg agccagggag taaaaaactg
    16261 acggtttcag aaagggagca acttccggcc gtttcgtctc aagcaaacgt tgggtatgct
    16321 tttgctccca cataaagcct ttccccagaa acaaaaaatg tcggcttacc ggtatggatt
    16381 cactggacat ctgataccgg ggtaaccgac ggatattgcg tcgatagcgc aagatgcgca
    16441 aaccctgacg agttctgatt gttgtgaaaa tggcaaaacc ggctgcagtc acataactga
    16501 cctgtggtgc taacgccatc gaccatggtg cgacaaccag aacaaaagtg gcagccccgc
    16561 cagccgcagc tgaatagagt tctactgctg gcctcaataa cgcctccatg acataacggt
    16621 tactcatagc tcctcctttc acactgttat gtaacaaccg gctgcccggc aactgacttt
    16681 gttactggcc ggtggtacca gcactggcgc cccgccagca aatcaagtag tcgctgcccg
    16741 ctgatcagtt gtattgttcg ccagcactgc aggtaattaa cgctcttact acccgtccgc
    16801 cctgtatgaa taaaaaatcc acaacattgc tcccgggtaa tcagctctcc gaactcacgt
    16861 atatgctgcg gagaaatagt ccgtctgtag cgttttgcct gaattaacca gcgctttccg
    16921 tcaataaaaa cctgcccgtc aagtccgcca tcgctactgt aggtctggtt tctcacaacc
    16981 aggagtccct gcctctcaaa cgccaacaac agcagctctt caaacacata cgggttaatt
    17041 tttcgaagat actttagacg ggccccgtct gaatcaagcg ctgtcagacg gcacagcaca
    17101 cgctccgcgt tctgtcggta gcgccggtgc cggcggtcgc gtgcggacgg cattttctta
    17161 cgccatatgg caggaatgag aagacagaaa agtaaaagaa gaatggcagt gatcatgaga
    17221 gcaccctact gggccagacc ggtggcggta atcaacaccg ggtagtggtt gagatgcaaa
    17281 cgacgcgcta tttcgcttgc cgatgccggt agcagaatga catcaggtat gatttgctga
    17341 agttccgaca acgcgtcctt atcgctgaca ttcaccacca gacctgtagc atgaagtcgc
    17401 ttaagctcat cacgccgcat cgtcaaccac tcgcgtgaaa gcgaatcatc cccaacaaga
    17461 aagaccggtg tcatcccgtt cagatttaac tcacgggctt ccactttccc tgcacgcatt
    17521 tccggtgtgg ttacgggcag catatcactt acatccgcag gggctgcggt tacagacgcg
    17581 cccgtggcgt tcagtgacct cggcggagtg aactcgttgt tcttattatt gatggcatca
    17641 aaaagcggcg ctgttggttc tccgccaaga tcagcaatca cattgagtgc tgccatcgat
    17701 gatgttgtca gcaaaatact gaccattaat gtcctgaaaa aaaaacagac agaataaagt
    17761 ttcactgacg ggactccctg ggttcaaccc attgcaattc acggttgtag tgtgagaaat
    17821 ggcgctgtga tggcgatatc tgtgcgatct gaagttcgga gtacgttact ggcgcgttta
    17881 aatccagtgt tgccagcttg cgtttcacga tggacttata gattcgtgct ggttttccac
    17941 ctgcaggatg gtgataacac cccgcggcct gtatccagct tcccggattg ttgtcataac
    18001 aggatttaag aatacgggcg gcaacccgaa ggttggtata tggatccagc gcttcgtagt
    18061 aactgctgaa ataagttcca ttccagccca ggttaacctg cgcgatccca acatcaatcc
    18121 gctttaacgg atagcgacgc atgaacgaca acattgcgtc atacgcttcc tggcgggagt
    18181 tataccgata ccctttcccg gcaacattga gtgtccacgg ccacggtcgc tctccatgtg
    18241 gtagttttcg ggatgtttct gcaagagaaa ctgaatacag ggcttcagcg ggtacgccga
    18301 cttcagttgc cacaaggtgg taacccgggg gaattgtttg cagaccgcgt cccttttcta
    18361 ccgcagctgc actaccaaca cccccgataa gaaggatcag aacagggacg ctgtatctgg
    18421 ctgctgtcag aatgctgcga tttgccatcc ggagactccc tgctgaagca taaccggcat
    18481 atatccctga ccatacttca gccagttgcc gttatcgtgg ttgagggtta tctgccggct
    18541 acgaacttta tcgaccggaa tatgatgtgc aagcgcccac tggcgaatgg tgtcatcact
    18601 gccgccactg tcgaccaggt aaatatcaac cggacggtta tctgccagaa ccgcacttac
    18661 tctggcatcg cacggtacac agttgcgctt cacaaataac gccagtcttc cctgtgtatc
    18721 atgggcaata ccgctggcat tgcccatgtt tacggagaga gtattgggat aaaggcgttt
    18781 ccaggcagca tccacttccc gctgaaaggc cagctccttt tcaccccggg catactcttc
    18841 cttcacccac atttcagcaa aacgccggcg ttcgcttgcc gaaccggcct ccagccccag
    18901 tgccatcaac gggtcaatgc caggtgactg aaatgctctg ggacctttaa gtacctgttg
    18961 atactgctgc cattcttttt cgctgagtcc ccatgccgtt cctgacgttt gcgtccttcc
    19021 ttctgtagtc gtattttgct gctggggtgc gcttacactg cgacccgtac tcactgatgc
    19081 aagagcaggc agacttacga taacagccag catgactgac gcagtccact gccggaggca
    19141 atttaacgtt gatttcatcg gtttcatcca atatttctcc ctgattcaga gcgttaaacg
    19201 ttgtacctgc ccgttaacct gaaactcagc ctggttaccg ctgatgttca ccagcaccca
    19261 gcctgacaga ctctctcctg ggcttaccat gcgcagctgt gtccagccac tgttccccgc
    19321 cggcagaata acggcgtaag cctgccctcc cctgcgttca atactcacca atgtgaaagg
    19381 cggcttaatg acccgtggtt ttgacgactt ttttgcggca gactgtccac ctccgggaga
    19441 cggggtcgcc ttcgtggcag tcgccacagt gcgtttgctc cacgtgtctt tccaagacgc
    19501 gagggtatct atacgcgaag tctgctcagt cagcgcttta tgaacagcgt cgagcttcat
    19561 gcccgtttca tcctctcggg caacagccct ggcagtcgcc gcctgagtct ctttaacctc
    19621 tgtaaccagc gaagaaagtt gctgctcaaa cgcggtgagc cgcagctcct gctcactcag
    19681 cctgagctgc catttttctc cctgcagttt cggaacgaat tgttgctgcc tgtcttctat
    19741 ggcctgcata cgatcgggaa gtgtctgcag ctgtccgctg cggaacgccg catcaagggt
    19801 ggtaagctgt atctgctgct gacgtactgt cagccagagg aataagacag cacccagtaa
    19861 taagcagtac accagaacgg atgacacttt aaatatgagg gaacggcggt ctgaagaagg
    19921 atgccacaga cgactcctct ttccccccag tcggtatgca gctgactgtg ctgaagtatc
    19981 tggtgtaaca gtgatatcag acgtatcaat agccggttcg gcaggttcag tgaggtgagc
    20041 ggataaaggt aaatcattat ctgacggaat atcgacagaa gatgccgtcg ttgtcgtcat
    20101 ggtataagtc ctccggaaaa cggttttcgc catgactatg caaaaacagt tcagcggata
    20161 cgacagacaa atcaaaactc aaaagtgaaa ataagggatc cagattagcg tcaggaacac
    20221 aaactggcag cctcttgaag atatgtgcga tatggagata aagcgttgac ggggctcttt
    20281 gccgccccac accccgcaga ctgcgtcgcc accattcccc gtcagcgggc aatgccggca
    20341 acgcagtgat gatctccctg taagtcatca cttcaaccct gcgataggcg cctgccagtt
    20401 cattaagcca tgcctgcaag cgaccagttc ctgtgaaggc gaagttttaa gcctaacccc
    20461 ctgtcatggt tagttcaccc agtacgtcag ttcttcagca acatgccagt tgacgccatc
    20521 cttataagtt gttgccgcat tcgcagttcc tgataaagcg ataagaacag agaaatacac
    20581 ccgtttttat ttcataaatt gattaatcag gaaatgcttg gaaattcacc cttaggttta
    20641 tcgaatatca tagcaggaat aaccgcccca ttatccaatg cctgcatttg tcgcgctgag
    20701 aaagtgaaat aacgtaatcg gataggagga tatttttcta ctttatcttt tgtatacccg
    20761 ccaagagtga tactggttat acgccgcaat tgattatatg cctgctgaac ctgctcatcc
    20821 tgccagtcta gtgcctgata taccctgagg agcccgatcg gctcacccga aataaggggg
    20881 cgatagcgca gacacaaccc cacactttga ggtttacgcc cctgctgcca gaagaaaatt
    20941 aactcaaccg gatccactga ctgaattgac tgcagacggc ataacagaga gggggtctgc
    21001 acagcccagt cgcgctggcc gtcagccata tctaccggat aggaagagtt tcccagcagc
    21061 cagttaacat ccacatcaaa ccatgtcgac aattgctgca gcaaaggttt gttcaggaga
    21121 tcaagcgtcc tatcctgact cgctaataca ctggccctta ttccccagga agccagtagc
    21181 tgtgcctgtt cgataacatt caatccatga gcatccaaca gcagacagaa tcgctcataa
    21241 agcgtggacg ttctgtccgc tatactctct ctcgcctctg ctacaatgcc atcaatacac
    21301 ataccaaaca tagcggcccg ggatataccc agatgctctg cgcacctgtc cagaaatacc
    21361 cgagtttccg gccgtattct tactgaaaac tgtgcactgg gtgcagatac tgatgccccc
    21421 gtttcaagtg gtatttcacc agatcgcatt aatgcaatta gcgcgttata agttgcattc
    21481 atactgacaa ccttaaatat tttcctggat acaaaagagt gaaattcaac tcatttcat
//
LOCUS       DAJVBX010000064        20870 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.064, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000064 DAJVBX010000000
VERSION     DAJVBX010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 20870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20870
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.064"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            101..658
                     /locus_tag="OPV72_002037"
     CDS             101..658
                     /locus_tag="OPV72_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtfJ family protein"
                     /protein_id="HCR9914337.1"
                     /translation="MTLRKILAMSCLLLPIMACAHNLEDNQRVPPVGIADRGELTLNK
                     DEFSYKNWNSAQLAGKVRVLLHIAGRTSAKEKNATLIEAIKSAKLPHDRYQTTTIVNT
                     DDAIPGSGMFVRSSIESNKKLYPWSQFIVDSNGVARNAWQLKEEGSAVIVLDKDGRVQ
                     WVKDGALTQQEVQQVVDLLHKLLSK"
     gene            complement(648..1388)
                     /gene="cysQ"
                     /locus_tag="OPV72_002038"
     CDS             complement(648..1388)
                     /gene="cysQ"
                     /locus_tag="OPV72_002038"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'(2'),5'-bisphosphate nucleotidase CysQ"
                     /protein_id="HCR9914338.1"
                     /translation="MLEQVCQLARNAGDAIMQVYDGAKPMEYARKQDDSPVTAADIAA
                     HTVILEGLRTLTPDIPVLSEEDPPAWEVRQHWQRYWLVDPLDGTKEFIKRNGEFTVNI
                     ALIEQGKPVLGVVYAPVLKVMYYAAEGKAWKEECGVRKQIQVRDARPPLVVISRSHTD
                     DELTEYLQQLGEHQTTSIGSSLKFCLVAEGQAQLYPRFGPTSVWDTAAGHAIAVAAGA
                     HVHDWQGKTLDYTPRESFLNPGFRVTIY"
     gene            1655..3598
                     /locus_tag="OPV72_002039"
     CDS             1655..3598
                     /locus_tag="OPV72_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2',3'-cyclic-nucleotide
                     2'-phosphodiesterase/3'-nucleotidase"
                     /protein_id="HCR9914339.1"
                     /translation="MIKFSATLLATLIAASVNAATVDLRIMETTDLHSNMMDFDYYKD
                     TATEKFGLVRTASLIHAARNEVKNSVLVDNGDLIQGSPLGDYMAAKGLKDGDVHPVYK
                     ALNTLDYAVGNLGNHEFNYGLDYLHNALAGAKFPYVNANIIDVKTQKPLFTPYLIKET
                     SVIDKDGHPHTLKIGYIGFVPPQIMIWDKANLSGKVTVNDITETARKYVPEMREKGAD
                     IVVVIAHSGLSADPYHSMAENSVYYLSEVPGVDAIMFGHAHAVFPGKDFADIKGADIA
                     KCTLNGIPAVMPGMWGDHLGVVDLVLNNDSGKWQVTQAKAEARPIYDAAAKKSLAAED
                     SKLVGILKADHDATREFVSKPIGKSADNMYSYLALVQDDPTVQVVNNAQKAYVEHFIQ
                     GDPDLAKLPVLSAAAPFKVGGRKNDPASFVEVEKGQLTFRNAADLYLYPNTLVVVKAS
                     GKEVKEWLECSAGQFNQIDIHSNKPQSLINWDGFRTYNFDVIDGVNYQIDVSQPARYD
                     GECQMVNPQAERIKNLTFNGKPVDPNATFLVATNNYRAYGGKFAGTGDSHIAFASPDE
                     NRAVLAAWIGAESKRAGEIHPAADNNWRLAPIHSDTALDIRFETSPGDKAAAFIKEKG
                     QYPMKKVGVDDIGFAIYQVDLSK"
     gene            complement(3656..4042)
                     /locus_tag="OPV72_002040"
     CDS             complement(3656..4042)
                     /locus_tag="OPV72_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HCR9914340.1"
                     /translation="MRAHTLSRQLREGNLFAEQCPSREVLKHVTSRWGVLILVALRDG
                     THRFSDLRRKMGGVSEKMLAQSLQALEQDGFLNRVSYPVVPPHVEYSLTPLGEQVSDK
                     VAALADWIELNLPQVLAQRERLSDGG"
     gene            4130..4978
                     /locus_tag="OPV72_002041"
     CDS             4130..4978
                     /locus_tag="OPV72_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCR9914341.1"
                     /translation="MIAITGATGQLGQHVIENLLKTTPASHLVAIVRNPKKAAPLSQR
                     GIAVRQADYANEAALTTALQGVDKLLLISSSEVGQRTAQHRNVIQAVIAAKVKFIAYT
                     SLLHADKSPLALADEHIETEKMLAESGIPHTLLRNGWYTENYLASVPAALKHGVFIGA
                     AGEGKIASAMRADYAAAAARVIREEGHAGNVYELAGDNAWTLSQLADELTHQSGKKIV
                     YQNLSEVDFAAALKGAGLPDGLADMLANSDAGAAKGGLFDDSHTLRKLIGRPTTALTE
                     SLRSVL"
     gene            5059..6024
                     /locus_tag="OPV72_002042"
     CDS             5059..6024
                     /locus_tag="OPV72_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HCR9914342.1"
                     /translation="MISGVLYALLAGLMWGLIFVGPLIVPDYPALLQSMGRYLALGLI
                     ALPIAWLGRTRLRQLTRKDWSTALSLTLMGNVIYYACLASAIQRTGAPVSTMIIGTLP
                     VVIPLFANVLYSQRDGRLSWLRLAPALALIGFGLLCVNIAELSQGLSDVSGWRYGSGI
                     VLALISVACWAWYALRNARWLRENPDKHPMMWATAQALVTLPVSLIGYAATCLWLSIQ
                     NPMFTLPFGPHPALFIGLMIAIAVLCSWVGALCWNIASQKLPTVILGPLIVFETLAGL
                     LYTFILRQEIPPFLTLSGIALLVAGVVIAVRAKPEKATVVPVTER"
     gene            6127..6789
                     /gene="ytfE"
                     /locus_tag="OPV72_002043"
     CDS             6127..6789
                     /gene="ytfE"
                     /locus_tag="OPV72_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster repair protein YtfE"
                     /protein_id="HCR9914343.1"
                     /translation="MAYRDQPLGELALSIPRASALFRQYDMDYCCGGKQTLARAAARH
                     DVDIDIIEAQLAQLAEQPIEKDWRAVPLADIIDHIVVRYHDRHREQLPELILQATKVE
                     RVHADKPNVPRGLTKYLTALHEELSSHMMKEEQILFPMIKQGMGRQATGPISVMESEH
                     DEAGELVDVIKHVTQNVTPPPEACTTWKAMYNGINEMIDALMEHISLENNVLFPRALA
                     GE"
     gene            complement(6856..8244)
                     /locus_tag="OPV72_002044"
     CDS             complement(6856..8244)
                     /locus_tag="OPV72_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000944334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914344.1"
                     /translation="MLRIKQFCLSILLMLAPVLALACSDIPYALFHYQPWGQGTKYVV
                     EEDYGYSINFKDIEIREVKFSQLRHVPDRIVNEYNDRGKMSNDFVHVAAFSSLIKNDF
                     WQFYWLTDGQHILWAGKIVQNPPGKPPVDAATFRAYGRFAADKDSLYFDGERTDDNHG
                     EKRVDMDSLQQVGGNIKLRDSGDVLKDRRNLYFQGRWLASAQGYSILGVKSWEQRNIL
                     FSPTSCDTTSNPGPWDTILRTATQVFVNGVAIDADPNSFHVVRWVAGVQLLYRDKAGV
                     KRYYFGKDCLNTFNVQRDKVTWMTREASRRGDDCRIATIPNVDPEYFHPIHYNWTVAQ
                     YKDLLYQVKYVSPVDRVLTITRLPDPQVQLKAGANLVGKQIYFIGDGGVQIIDLIGPL
                     VWFKSPDGSFSDVFAHDDRYLYFFGDTLVDSGQRRNVTRTLDTAHIDKSGYYLVTEEG
                     KYEVINNAFTSR"
     gene            complement(8259..9398)
                     /locus_tag="OPV72_002045"
     CDS             complement(8259..9398)
                     /locus_tag="OPV72_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DKNYY domain-containing protein"
                     /protein_id="HCR9914345.1"
                     /translation="MTIRRWILSATLLLLPVPAFADFQYQQDKDGVFYTADDEPQILS
                     RLPDVSYSHLRRIADLSHPQDPRPLIEINPDSHNCDDNHICQHAYLSDGHFILWAGKI
                     VQNTGDEPAVDVASFQSFGAFAADKHGLYFDGKRRDSNAGEKRVDMATLAETKIWNLL
                     RDKNNLYYEGRWLGRADGFRVLRLDSTSAREFIVTTAQRVIVNGIPITADANTFQIIR
                     WMPGEVLIYRDKTGKHDYEIDNSSRYCGYFNIGLREVTWLKHEATNAGSSCKVETLPG
                     VDPEYFFRLNGNTGWYKDRIYQVSTNALGEGVLRIFTSQEKLPALKIDRVTYNYYHLA
                     LSADGQLYRQISRDQWQSYNPILTEWTTVSPAPTDVISLLPSDYH"
     gene            complement(9736..11139)
                     /gene="cycA"
                     /locus_tag="OPV72_002046"
                     /gene_synonym="dagA"
     CDS             complement(9736..11139)
                     /gene="cycA"
                     /locus_tag="OPV72_002046"
                     /gene_synonym="dagA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001541380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-serine/D-alanine/glycine transporter"
                     /protein_id="HCR9914346.1"
                     /translation="MVDQVKVAADEQAPAEQSLRRNLTNRHIQLIAIGGAIGTGLFMG
                     SGKTISLAGPSIIFVYMIIGFMLFFVMRAMGELLLSNLEYKSFSDFASDLLGPWAGYF
                     TGWTYWFCWVVTGMADVVAITAYAQFWFPGLSDWVASLAVVVLLLSLNLATVKMFGEM
                     EFWFAMVKIVAIVALIVVGLVMIAMHFKSPTGVEASFAHLWNDGGWFPKGISGFFAGF
                     QIAVFAFVGIELVGTTAAETKDPEKSLPRAINSIPIRIIMFYVFALIVIMSVTPWSSV
                     VPDKSPFVELFVLVGLPAAASVINFVVLTSAASSANSGVFSTSRMLFGLAQEGVAPKA
                     FAKLSKRAVPAKGLTFSCICLLGGVVMLMVNPSVIGAFTMITTVSAILFMFVWTIILC
                     SYLVYRKKRPHLHEKSIYKMPLGKLMCWVCMAFFAFVLVLLTLEDDTRQALIVTPLWF
                     IALGLGWLFLRKNKLAK"
     gene            complement(11435..12055)
                     /gene="fklB"
                     /locus_tag="OPV72_002047"
     CDS             complement(11435..12055)
                     /gene="fklB"
                     /locus_tag="OPV72_002047"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015742582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HCR9914347.1"
                     /translation="MATPTFDTIEAQASYGIGLQVGQQLSESGLEGLLPEALVAGIAD
                     ALEGKHPAVPVDVVHRALREIHERADAVRRERFKAMAAEGVKYLEENREKDGVNSTES
                     GLQFRVLTQGEGAIPARTDRVRVHYTGKLIDGTVFDSSVARGEPAEFPVNGVIAGWIE
                     ALTLMPVGSKWELTIPQELAYGERGAGASIPPFSTLVFEVELLEIL"
     gene            12275..12910
                     /locus_tag="OPV72_002048"
     CDS             12275..12910
                     /locus_tag="OPV72_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OapA family protein"
                     /protein_id="HCR9914348.1"
                     /translation="MPGRFELKPTLAKIWHAPDNFRIMEPLPPMHRRGIIIAAIVLVI
                     GFLLPASETSDSPVVTREAQLDLQSQSQPPTEAQLQAQLVAPQNDPDQVAPVASEPIQ
                     EGQPEEQNQPQTQPFQQDSGIGQQWRSYRVEPGKTLAQLFRDHGLPPTDVYAMAQVEG
                     AGKPLSNLKNGQMIKIRQNASGVVTGLTIDGDNGQQVLFTRQPDGSFIRAQ"
     gene            complement(12960..13886)
                     /locus_tag="OPV72_002049"
     CDS             complement(12960..13886)
                     /locus_tag="OPV72_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HCR9914349.1"
                     /translation="MDTQRQASPFARKNVVYVCAAFCCLLWGSAYPAIKSGYDLFQIA
                     TDDIPSKIVFAGYRFLFAGGLLLLFALLQRKPIGRFRPRQFAQLTLLGLTQTSLQYLF
                     FYIGLAFTSGVKGSIMNATGTFFSVLLAHFIYQNDRLSYNKTLGCILGFAGVMVVNVS
                     NGLDFSFNLPGEGSVVLAAFILSAATLYGKRLSQTVDPMVMTGYQLGIGGLVLVIGGY
                     VFGGTLTIHGFSSVAILVYLTLLSSVAFALWNILLKYNRVGMIAPFNFLIPVSGAALS
                     AIFLGENILEWKYMIALVLVCSGIWWVNKVKR"
     gene            complement(14034..14483)
                     /gene="rplI"
                     /locus_tag="OPV72_002050"
     CDS             complement(14034..14483)
                     /gene="rplI"
                     /locus_tag="OPV72_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005134442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HCR9914350.1"
                     /translation="MQVILLDKVANLGSLGDQVNVKAGYARNFLVPQGKAVPATKKNV
                     EYFEARRAELEAKLADVLAAANARAEKINALETVTIASKAGDEGKLFGSIGTRDIADA
                     VTAAGVDVAKSEVRLPNGVLRTTGEHEVNFQVHSEVFAKVIINVVAE"
     gene            complement(14525..14752)
                     /gene="rpsR"
                     /locus_tag="OPV72_002051"
     CDS             complement(14525..14752)
                     /gene="rpsR"
                     /locus_tag="OPV72_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012986941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HCR9914351.1"
                     /translation="MARYFRRRKFCRFTAEGVQEIDYKDIATLKNYITESGKIVPSRI
                     TGTRAKYQRQLARAIKRARYLSLLPYTDRHQ"
     gene            complement(14757..15071)
                     /gene="priB"
                     /locus_tag="OPV72_002052"
     CDS             complement(14757..15071)
                     /gene="priB"
                     /locus_tag="OPV72_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal replication protein N"
                     /protein_id="HCR9914352.1"
                     /translation="MTNRLTLSGTVCRAPLRKVSPSGIPHCQFVLEHRSVQEEAGFHR
                     QAWCQMPVIVSGHENQAITHSITVGSRITVQGFISCHKAKNGLSKMVLHAEQIELIDS
                     GD"
     gene            complement(15078..15473)
                     /gene="rpsF"
                     /locus_tag="OPV72_002053"
     CDS             complement(15078..15473)
                     /gene="rpsF"
                     /locus_tag="OPV72_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020456251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HCR9914353.1"
                     /translation="MRHYEIVFMVHPDQSEQVPGMIERYSAAITGAEGKIHRLEDWGR
                     RQLAYPINKLHKAHYVLMNVEAPQEVIDELETTFRFNDAVIRSMVMRTKHAVTEASPM
                     VKAKDERRERRDDFANETADDAEAGDSEE"
     gene            complement(15544..15750)
                     /locus_tag="OPV72_002054"
     CDS             complement(15544..15750)
                     /locus_tag="OPV72_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914354.1"
                     /translation="MWQKSTLTTVSIFLPQQAVYSGMRYEVNISAAKCDGTGVTFGTI
                     NNCTITLSLPAGASIITRHFSADL"
     gene            15944..16219
                     /locus_tag="OPV72_002055"
     CDS             15944..16219
                     /locus_tag="OPV72_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HCR9914355.1"
                     /translation="MRARIMLFLAALLPGITATAAIELNNHQATNMDDVRSLGVIYIN
                     HNFATESEANLALNDEADARNAMYYHAILIREPGSNGNIHASANIYR"
     gene            complement(16349..17035)
                     /locus_tag="OPV72_002056"
     CDS             complement(16349..17035)
                     /locus_tag="OPV72_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HCR9914356.1"
                     /translation="MQKLKQQVFDANMDLPRYGLVTFTWGNVSAIDRERGLVVIKPSG
                     VAYETMKVDDMVVVDMDGKVVEGRYRPSSDTATHLALYQRYPSLGGVVHTHSTHATAW
                     AQAGMAIPALGTTHADYFFGDIPCTRALSEEEVQGEYELNTGKVIIETLGEVEPLHTP
                     GIVVYQHGPFAWGKDAHDAVHNAVVMEEVARMAWIARGINPGLNPIDDYLMNKHFMRK
                     HGPNAYYGQK"
     gene            complement(17035..17889)
                     /gene="ulaE"
                     /locus_tag="OPV72_002057"
     CDS             complement(17035..17889)
                     /gene="ulaE"
                     /locus_tag="OPV72_002057"
                     /EC_number="5.1.3.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase UlaE"
                     /protein_id="HCR9914357.1"
                     /translation="MLSKQIPLGIYEKALPAGECWLERLRLAKTLGFDFVEMSVDETD
                     ARLARLDWSREQRLALVSAVAETGVRVPSMCLSAHRRFPLGSEDDAVRAQGLEIMRKA
                     IQFAQDVGIRVIQLAGYDVYYQQANDETRCRFRDGLKESVDMASRAQVTLAMEIMDYP
                     LMNSISKALGYAHYLNNPCFQLYPDIGNLSAWDNDVQMELQAGIGHIVAVHVKDTKPG
                     VFKNVPFGEGVVDFERCFETLKQSGYCGPYLIEMWSETAENPAAEVAKARDWVKARMA
                     KAGMVEAA"
     gene            complement(17899..18549)
                     /gene="ulaD"
                     /locus_tag="OPV72_002058"
     CDS             complement(17899..18549)
                     /gene="ulaD"
                     /locus_tag="OPV72_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HCR9914358.1"
                     /translation="MSLPMLQVALDNQTMDSAYETTRLIAEEVDIIEVGTILCVGEGV
                     RAVRDLKALYPHKIVLADAKIADAGKILSRMCFEANADWVTVICCADINTAKGALDVA
                     KEFNGDVQIELTGYWTWEQAQQWRDAGIQQVVYHRSCDAQAAGVAWGEADITAIKRLS
                     DMGFKVTVTGGLALEDLPLFKGIPIHVFIAGRSIRDAESPVEAARQFKRSIAQLWG"
     gene            complement(18563..19027)
                     /gene="ulaC"
                     /locus_tag="OPV72_002059"
     CDS             complement(18563..19027)
                     /gene="ulaC"
                     /locus_tag="OPV72_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIA"
                     /protein_id="HCR9914359.1"
                     /translation="MKLRDSLAENNSIRLQAEANTWQEAVKIGVDLLVAADVVEPRYY
                     QAILDGVEQFGPYFVIAPGLVMPHGRPEEGVKKTGFSLVTLKKPLEFNHEDNDPVDIL
                     ITMAAVDANTHQEVGIMQIVNLFEDEANFDRLRACRTAQEVLDLIDRTNAAA"
     gene            complement(19037..19341)
                     /gene="ulaB"
                     /locus_tag="OPV72_002060"
                     /pseudo
     CDS             complement(19037..19341)
                     /gene="ulaB"
                     /locus_tag="OPV72_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710059.2"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIB"
     gene            complement(19357..20754)
                     /gene="ulaA"
                     /locus_tag="OPV72_002061"
     CDS             complement(19357..20754)
                     /gene="ulaA"
                     /locus_tag="OPV72_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418614.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HCR9914360.1"
                     /translation="MEILYNIFTIFFNQVMTNAPLLLGIVTCLGYILLRKSVSVIIKG
                     TIKTIIGFMLLQAGSGILTSTFKPVVAKMSEVYGINGAISDTYASMMATIERMGDAYS
                     WVGYAVLLALALNICYVLLRRITGIRTIMLTGHIMFQQAGLIAVSFYIFGYSMWTTII
                     CTAILVSLYWGITSNMMYKPTQEVTDGCGFSIGHQQQFASWIAYKVAPFLGKKEESVE
                     DLKLPGWLNIFHDNIVSTAIVMTIFFGAILLSFGIDTVQAMAGKVHWTVYILQTGFSF
                     AVAIFIITQGVRMFVAELSEAFNGISQRLIPGAVLAIDCAAIYSFAPNAVVWGFMWGT
                     IGQLIAVGILVACGSSILIIPGFIPMFFSNATIGVFANHFGGWRAALKICLVMGMIEI
                     FGCVWAVKLTGMSAWMGMADWSILAPPMMQGFFSIGIAFMAVIIVIALAYMFFAGRAL
                     RAEEDAEKQLAEQSA"
BASE COUNT         5239 a         5689 c         5235 g         4707 t
ORIGIN      
        1 ctggcatccc ctttgcggga aaaagcatca atcgcacata tgattaactg tcggcccaaa
       61 gtggtcggat cacctgcaaa aaaataaaga aggaatgacc atgaccctac gtaaaattct
      121 ggcgatgtcg tgtctgctac tccccataat ggcttgtgcg cataaccttg aagataacca
      181 acgggtgccg ccggtaggca ttgccgatcg tggcgaactg acgttgaata aagatgagtt
      241 tagttataaa aactggaata gcgcgcagct ggcgggaaaa gtgcgcgtcc tgctgcacat
      301 tgcgggtcga acgtcagcga aggaaaaaaa cgccacgctg attgaagcga ttaaatcagc
      361 caagctcccg catgacagat accagacgac cacaattgtg aacaccgatg atgcaatccc
      421 aggctccggt atgttcgtgc gtagcagtat agaaagtaat aaaaagctct acccgtggtc
      481 gcaatttatt gtcgacagca atggcgtggc gcgtaacgcc tggcaattaa aagaagaggg
      541 gtccgccgtc atcgtgcttg acaaagacgg tcgggttcaa tgggtgaaag atggcgcgtt
      601 aacccagcaa gaggtacagc aggtggtcga cctgctgcat aagctcctca gtaaatagtc
      661 acccggaagc cggggttaag gaacgattca cgaggggtat agtccagcgt ttttccctgc
      721 cagtcgtgaa cgtgcgcccc ggctgcaacg gcaatggcat gacctgcggc agtatcccag
      781 acgctggtcg gcccaaatct ggggtaaagc tgcgcctgtc cttccgccac aagacagaat
      841 ttcagcgagg aaccaataga ggtagtctga tgttcgccaa gctgttggag atattcggtg
      901 agttcatcat ccgtatgcga acggctaatc accaccagcg gcgggcgggc atcccgcacc
      961 tgaatctgct tacgcacccc gcactcctct ttccaggcct taccttccgc cgcgtagtac
     1021 atcactttca gcaccggcgc atagacaacg cccaacaccg gcttgccctg ctcaatcagc
     1081 gcgatattga ccgtgaattc tccattgcgc ttgatgaatt ctttggtgcc gtcgagcgga
     1141 tcgaccagcc agtaacgctg ccagtgctgg cgcacttccc aggcgggcgg atcttcttct
     1201 gaaagcaccg gaatatccgg cgtgagcgtg cgtaaccctt cgagaatcac ggtatgtgcg
     1261 gcgatatccg ccgcagtgac tggagaatcg tcctgcttgc gggcgtactc catcggtttg
     1321 gctccatcat aaacctgcat aatggcatcg cccgcgttcc gtgcaagctg gcatacttgt
     1381 tctaacattc tccacctctt tatgacgggg gcgttaactc gttgttttac ttatacccga
     1441 tcgttaaggg ttccgccaac tgtgataccg tcagcggttt tgataatagc tttcatggca
     1501 tgattcacct ttctgtgaac actcgcaaaa aatcggccgg atggggcggt ttcgccttct
     1561 tctggcgacg gtcggaacga taccggtttc actgtttatc atcgctattt ttcactatcc
     1621 ggcttttcta ttgcgttctt aaaaggtgcc tctgatgatt aagtttagtg caacgcttct
     1681 ggctacgctg atcgccgcca gcgtgaatgc ggccaccgtc gatctccgta tcatggaaac
     1741 tactgattta catagcaaca tgatggattt cgattattac aaggataccg caaccgaaaa
     1801 attcggattg gtacgtaccg caagtttgat tcatgccgcc cgaaatgaag tcaaaaacag
     1861 cgtgctggtg gataacggcg acctgattca ggggagccct ctgggcgatt atatggcggc
     1921 aaaagggctc aaagacggtg atgttcaccc ggtctataaa gcgctcaata ctctggatta
     1981 cgcggttgga aacctcggca accatgagtt taattatggt ctggactatc tgcataacgc
     2041 gctggccggc gcgaaattcc cttatgttaa cgccaatatt atcgacgtta aaacccaaaa
     2101 gccgctcttt acgccttatc tgattaaaga gacgagcgtt attgataaag acggccaccc
     2161 gcacactctg aaaatcggct atatcggctt tgttccgccg caaatcatga tttgggataa
     2221 agcgaatctg agcggcaaag ttaccgtcaa tgacattacg gaaaccgccc ggaaatatgt
     2281 gcccgaaatg cgcgagaaag gcgctgatat cgtggtagtc attgctcact caggcctttc
     2341 tgccgatccg taccacagca tggcggaaaa ctcggtttat tacctcagcg aagttcccgg
     2401 cgtcgacgcg attatgtttg gtcacgccca cgccgtcttc cccggtaaag attttgccga
     2461 catcaaaggc gcggatatcg ccaaatgtac gcttaacggc attcctgcgg taatgccagg
     2521 catgtggggc gaccatctgg gagtggtcga tctggtgctc aataacgaca gcggcaaatg
     2581 gcaggttacg caggcgaaag cggaagcgcg gcctatttac gacgccgccg ctaaaaagtc
     2641 gctggcggcg gaagacagta agctggtcgg tattctgaaa gccgatcacg atgccacccg
     2701 cgagtttgtc agcaagccca tcggtaaatc cgccgataat atgtacagtt atcttgctct
     2761 ggtgcaggac gatcctaccg tacaggtggt gaataacgcg caaaaagcgt atgtggaaca
     2821 ctttattcag ggcgatccgg atctggcgaa actgccggtg ctgtccgccg ccgcgccgtt
     2881 taaagttggc gggcgtaaga acgatcctgc cagctttgtc gaggtggaaa aaggccagct
     2941 gaccttccgt aacgccgcgg atctttatct ctatccgaat acgctggtgg tggtgaaagc
     3001 cagcggcaag gaggtaaaag agtggctgga atgttctgcc ggacagttta atcagattga
     3061 tattcacagc aacaaaccgc aatcgttgat caattgggat ggctttcgca cctataattt
     3121 cgatgtcatt gacggtgtga attatcaaat cgatgtgtca cagcccgccc gctatgatgg
     3181 cgaatgccag atggtgaatc cgcaggcgga acgtattaaa aacctgacct ttaacggtaa
     3241 gcctgtcgac ccgaacgcta cgttcctggt cgccacgaat aactatcgcg cttacggcgg
     3301 caagtttgcc ggcacgggcg acagccatat cgcctttgcg tctccggatg aaaatcgcgc
     3361 cgtgctggcg gcatggattg gcgcagagtc aaaacgcgcg ggcgaaatcc atccggcggc
     3421 ggataataac tggcgtctgg cgccaatcca cagcgatacg gcgctggata tccgctttga
     3481 aacatcgcca ggcgataaag ccgcggcctt cattaaagag aaagggcagt atccgatgaa
     3541 aaaggttggt gtcgatgata tcggttttgc catttatcag gtggatttga gcaagtaacg
     3601 tgagtcccgt atggcgctgc gtttattcgg cctgactggc aggccgaata aagcgctagc
     3661 cgccatctga taaacgctcc cgctgcgcca atacctgggg caaattcagt tctatccagt
     3721 ccgccagcgc ggcgacttta tcactcacct gctcgccaag cggcgtcagg ctgtactcca
     3781 catgcggcgg aacaactgga tatgacaccc ggttaagaaa tccgtcctgt tcaagcgcct
     3841 gtaacgactg cgccagcatc ttttcactca cgcctcccat cttgcggcgc aggtcgctaa
     3901 aacggtgtgt accgtcgcgt aacgcgacca gaatcagtac gccccagcga ctggtgacat
     3961 gttttaacac ctcacgggac gggcactgtt cagcaaagag attaccttca cgcaactgcc
     4021 gggaaagagt atgagcgcgc attgatactt acctttttgt acgtacttac taaaagtaag
     4081 tttaggtggt agcgtaataa aacacaagac caacactgag gagttcacca tgattgctat
     4141 cactggcgca acaggccaac tgggccaaca cgttattgaa aacctgctaa aaacgacgcc
     4201 cgccagtcac cttgtcgcga tcgtccgtaa cccgaaaaaa gccgccccgc tcagtcagcg
     4261 cgggattgcc gttcgccagg cggattacgc taacgaagct gcgctgacca ccgccttaca
     4321 gggcgttgat aaactgctgc tcatttcatc cagcgaagtg ggacaacgca ccgcgcagca
     4381 ccgcaacgtc attcaggccg tcattgccgc gaaggtgaaa ttcatcgcct ataccagcct
     4441 gctacatgcg gataaatcgc cgctggcgct cgccgatgaa catattgaaa cggaaaagat
     4501 gctggctgag tcaggtattc ctcacacgct attacgtaac ggctggtata cggaaaacta
     4561 cctggcgagc gtccctgccg cgctgaagca tggcgtcttt attggcgcgg cgggagaagg
     4621 gaaaatcgcc tccgcaatgc gcgctgacta tgccgccgcc gccgcgcgcg tcatccgtga
     4681 agagggtcac gccgggaatg tttacgagct ggcgggtgat aacgcctgga cattaagcca
     4741 gttggcggat gaacttactc atcagagcgg aaaaaaaatc gtctaccaga acctgagcga
     4801 agtcgatttt gccgccgcgc tgaaaggcgc aggcctgcct gacggactgg cggatatgtt
     4861 ggccaattct gacgctggcg cggcgaaagg cggtctgttt gatgacagcc atacgctgcg
     4921 taaactcatc ggtcgcccga cgacggcgct cacagaaagc cttcgctccg tactgtaagt
     4981 gttaaaattt agttaattta tatggcatcc tcatagacct tctctgataa tgacggaacg
     5041 gtttatgagg agaatctgat gattagcggc gtgctatacg ccctgctggc agggctaatg
     5101 tggggattga ttttcgtcgg cccgttaatc gtgccggatt acccggccct cttacagtca
     5161 atgggacgct atctggcgct ggggctgatt gccctgccga ttgcctggtt aggccgcacg
     5221 cggttacgcc agttgacgcg caaagactgg tccaccgccc tgtcgctgac cctgatgggc
     5281 aatgtaatct attacgcctg cctcgccagc gccattcagc gaaccggcgc gccggtttcg
     5341 acgatgatca tcgggacatt gccggtcgtc attccgcttt tcgctaacgt tctctatagc
     5401 caacgagacg gcagattatc ctggctacgt ttagcgcccg cgctggcgct tatcggtttt
     5461 ggcctgctgt gcgtcaatat tgctgaactt agccagggat tgtccgatgt tagcggctgg
     5521 cgctatggtt caggcattgt gctggcgctg atttccgtag cgtgctgggc atggtatgcg
     5581 ctgcgcaacg cccgctggct gcgggaaaat cccgacaaac atcccatgat gtgggcaacg
     5641 gcgcaggcgc tggttacgct gccggtctcg ttaatcggct atgcggcaac ctgtctgtgg
     5701 ctgagtatcc agaacccgat gtttaccctg ccctttggcc cgcatcccgc gctgtttatc
     5761 ggtctgatga tcgccatcgc ggtgctgtgt tcctgggtgg gcgcgttgtg ctggaatatc
     5821 gccagccaaa aattgccaac cgtgatttta gggccgctga ttgtttttga aacgttggca
     5881 ggactgctct ataccttcat tctgcgccag gaaatcccgc cattcctgac gttaagcggc
     5941 attgcgctcc tggtggcggg cgtggttatt gccgtgagag cgaaaccgga aaaagcgacc
     6001 gtcgttccgg tcacggaacg ctaatctcat cctggcttaa attatacgca ccccgaaaga
     6061 gttatagcct cgccttaaag atgcatttaa aatacaactt atattattgc aaatgaggta
     6121 acggctatgg cttatcgcga tcaaccttta ggcgaactgg cgctctctat tccccgcgca
     6181 tcggcgctgt ttcgccagta cgatatggat tactgctgcg gcggaaaaca gacgctggcg
     6241 cgcgccgccg ctcgtcacga cgtcgatatt gacattattg aagcgcaact cgcgcagttg
     6301 gctgaacagc ccatcgaaaa agactggcgc gccgttccgc tggcggacat tattgaccat
     6361 atcgttgtgc gctatcatga ccgacaccgc gaacaactgc cggagcttat cctgcaggca
     6421 accaaagtgg aacgcgttca cgcggataag ccaaacgtcc cacgcggcct gacaaaatat
     6481 ctcaccgcgc tgcatgaaga gctttccagc catatgatga aagaagaaca gatcctgttc
     6541 cccatgatca aacagggtat gggtcgccag gcaacgggcc cgataagcgt aatggaaagc
     6601 gagcatgacg aggcgggaga gctggtagac gtcatcaaac acgtcaccca aaatgtaacg
     6661 ccgccgccag aagcctgcac cacctggaaa gcgatgtata acggcattaa tgagatgatt
     6721 gatgctctga tggagcacat cagcctggag aataacgtgc tgttcccacg cgcgctggcc
     6781 ggggaataat ccatcgccaa taaacgatcc tgaacgcata gacaggatcg tttattctga
     6841 atcgactaac gctttttagc gagaggtgaa tgcattatta ataacctcat atttcccctc
     6901 ctcagtgacc agataataac cgctcttgtc gatatgcgca gtatccagcg tccgcgttac
     6961 gttacgccgt tgcccgctat ctaccagcgt atcaccgaag aaatagagat aacgatcgtc
     7021 atgagcaaaa acatcagaaa atgaaccatc gggactttta aaccacacca atggtccaat
     7081 aaggtcgata atctgcactc ccccatcgcc gataaaatag atctgtttac ccaccaaatt
     7141 agcgccagct ttcagctgta cctgcggatc aggcaagcgg gtgatggtta ataccctgtc
     7201 gaccggagag acatacttca cctggtacaa tagatctttg tactgtgcta ccgtccaatt
     7261 gtaatgaatg ggatggaaat attctggatc aacattggga atagtcgcta ttcggcagtc
     7321 atcgcctcgg cgcgatgcct ctcgcgtcat ccatgtcacc ttatcccgct gtacattaaa
     7381 cgtattgaga cagtctttgc cgaagtaata gcgttttacg cctgctttgt cgcgatagag
     7441 taactgcacg ccagcgaccc agcgcacaac atgaaaagag ttcggatcgg catcaattgc
     7501 cacaccatta acaaaaacct gcgtggcggt acgcagaata gtgtcccacg ggccaggatt
     7561 agatgtagta tcgcagctgg tcggcgaaaa cagaatatta cgctgctccc aggatttaac
     7621 gcccaggatg gaatatccct gcgcactagc cagccagcgt ccctgaaagt agaggttgcg
     7681 cctgtcttta agcacatcgc cggagtcgcg taatttgatg ttgccgccga cctgctgcaa
     7741 cgaatccata tcgacccttt tttcaccatg attatcatct gtgcgctcgc cgtcgaagta
     7801 aagactatct ttatcagcgg caaagcgtcc atacgcccga aaagtcgctg catccactgg
     7861 cggcttaccc ggtggatttt gtacgatttt cccagcccat aaaatatgct ggccgtcggt
     7921 tagccaataa aactgccaga aatcattttt tattagcgat gaaaaagcgg cgacatgaac
     7981 aaaatcatta ctcatttttc cacggtcatt atattcatta acaatgcggt caggaacgtg
     8041 ccgtagttga ctaaatttta cctctcgaat ttcaatatct ttaaaattaa tactataacc
     8101 ataatcttct tcaactacat atttcgttcc ctgcccccac ggctgatagt gaaacaaagc
     8161 atatggaatg tcggaacagg ccagagctaa cactggtgcc agcattaata aaatcgataa
     8221 acagaactgt tttattctca acattgcgcc atcctgcgct agtggtaatc agagggaagc
     8281 aaagagataa cgtcagtggg cgctggtgat accgtcgtcc actctgttaa tatcgggtta
     8341 tagctctgcc attgatcacg tgagatctgg cgatataatt gcccatccgc ggacaaagcc
     8401 agatggtagt aattataggt aactctatct attttcagcg ccggaagttt ttcctgcgac
     8461 gtaaaaatgc gcagcacccc ctcgcccaac gcattcgtgc tcacctgata aatacgatcc
     8521 ttataccaac cggtgttccc gttcagacga aaaaaatact ccggatcgac acccggcagg
     8581 gtttccactt tacaactgct cccggcgttg gttgcctcat gcttcagcca tgtcacctca
     8641 cgcaggccaa tattaaaata gccgcagtac cgactggaat tatcaatctc atagtcatgc
     8701 ttaccggttt tatcacgata aattagtacc tcgccaggca tccagcgaat gatttgaaac
     8761 gtattagcat cagcggtaat gggtatgccg ttcacaatca cccgttgcgc cgtcgtcaca
     8821 ataaactccc ttgccgaagt ggaatccagc ctcaacacgc gaaacccatc ggcccgcccc
     8881 agccagcggc cttcataata gagattattt ttatcccgca gcagattcca gattttcgtc
     8941 tctgccagag ttgccatatc cacacgtttt tcacccgcat tgctatcacg acgtttacca
     9001 tcaaaataga gaccgtgttt atcggcggca aaggcgccaa aagactgaaa gctggcaaca
     9061 tcaacggcag gctcatcccc ggtattctgg acgattttgc ctgcccacag gataaagtgc
     9121 ccatcgctga gataagcgtg ctgacaaata tgattgtcgt cgcagttatg gctgtcggga
     9181 ttgatttcta ttaacgggcg agggtcttgc gggtgagata aatcggcaat acgccgtaaa
     9241 tgcgaatagc taacgtcagg cagtcgggag agaatttgcg gttcgtcgtc ggcggtataa
     9301 aaaacgccgt ccttatcctg ctgatactga aaatctgcga acgcgggaac gggcagcagc
     9361 aaaagcgtag cgcttaaaat ccagcgtcga atggtcataa ttacagtttg aaataggaga
     9421 ttaatttgtt acttaaacca ctttttcaac gtattatcca gcgcgagccg ccattatagg
     9481 aattcatcaa ggcggcactt accgtcagcc tgcaatttac agctgccctt cctgaagaaa
     9541 cgtttttcgc gtcattgcat cagcggacaa acactcattt cctgagcttt tcatctccat
     9601 acgctatcaa atgtggcgag aaaaatagct cgttaaggag cgggaagcga caaaatgggg
     9661 cgtaaaaatg aagaaagcgc cccggcgggt acgttatgcg cataccccct cgcctaagcg
     9721 agagggataa atccgtcatt tagccagttt gttcttacgc aggaacagcc agcccagacc
     9781 caacgcgata aaccacagcg gcgtcacgat cagcgcctgg cgcgtatcat cttccagcgt
     9841 cagcaatacc agcacgaacg caaagaacgc catgcagacc cagcacatca gcttaccgag
     9901 cggcatctta tagatggatt tttcatgcag gtggggacgc tttttgcggt acaccaggta
     9961 tgaacacaga atgatggtcc agacaaacat aaacaggatg gccgaaaccg tagtgatcat
    10021 ggtgaatgcg ccaatcacgc tcgggttgac catcagcata accacgccgc ccagcaggca
    10081 gatacaggag aaggtcaggc ctttcgccgg taccgcgcgt ttcgatagct tagcgaacgc
    10141 ttttggcgcc acgccttctt gcgccaggcc aaacagcata cggctggtcg agaagacgcc
    10201 gctgttggcg gaagacgccg ccgaggtcag cacaacaaag ttgatcacgc tcgcggcggc
    10261 aggcagaccc accagtacaa acagctcaac aaacgggctc ttatccggta cgactgaact
    10321 ccacggcgtt accgacataa tgacaatcag cgcaaagacg tagaacatga tgatacggat
    10381 cggtattgag ttgatcgcgc gcggcagcga tttttccgga tctttagttt ctgcggcggt
    10441 agtaccgacc agctcaatgc ccacgaaggc gaacaccgca atctggaaac cggcaaagaa
    10501 cccgctaata cctttcggga accagccgcc gtcattccac agatgcgcga aagacgcttc
    10561 aacgccggtc ggcgatttaa agtgcatcgc aatcatcacc aacccaacca caatcaacgc
    10621 cacgatggcg acgattttga ccatagcaaa ccaaaattcc atttcaccaa acattttaac
    10681 ggtggcgagg ttgaggctta gcagcaggac cactaccgcc agcgaggcga cccaatcgga
    10741 aaggccggga aaccagaact gcgcgtaggc ggtaatcgcc accacgtcag ccataccggt
    10801 cactacccag caaaaccagt acgtccagcc ggtgaaatat cccgcccagg ggccaagcag
    10861 gtcggaagca aaatcgctaa acgatttata ttccagattc gagagcagca attcccccat
    10921 ggcgcgcatc acgaaaaaaa gcataaaacc gatgatcata tacacaaaaa tgatcgacgg
    10981 tccggcgaga ctgatcgttt tacccgatcc cataaacaga ccggtaccaa tagcgccgcc
    11041 aatagcgata agctgtatat gacggtttgt aagattgcgc cgtagcgact gttcagccgg
    11101 agcctgttcg tcggctgcga cttttacctg atctaccatg tttttcttcc tgtacctgtc
    11161 tgtgttgtgc gggctctacg gcctttggtc tatgatacga cgatcctgtt atcaggactc
    11221 atcgatatta ggtaagaatc ggcgggatga atactaagat tcaaatacaa tgttaatttt
    11281 atgtttaaaa tgagtgttat atcactttga taatgcgaat tatctcacaa aaatacacgt
    11341 aacgacgcca tttgcaaaat aaaatattgg catctgctga agtcagggtt gccggataag
    11401 gcgtttacgc catcatccgg caaacccggg gcgcttacag aatttccagc agttccacct
    11461 caaacaccag ggtgctgaat ggcggaatag atgccccggc cccacgctcg ccataggcca
    11521 gctcctgtgg gatagtcagt tcccatttgg aacctaccgg catcagagtc agcgcttcaa
    11581 tccagccggc gatcacgcca tttaccggga attcagccgg ttcgccgcgc gcgacggagc
    11641 tgtcaaatac ggtgccatca ataagcttac cggtgtaatg cacgcgtacg cggtcggtac
    11701 gcgccggaat cgcgccttcg ccctgcgtca gaacgcggaa ctgtaaacca gattcagtac
    11761 tgttcacacc gtctttttcg cggttttctt ccaggtattt cacgccttcg gccgccattg
    11821 ctttgaaacg ctcacgacgc accgcgtccg cacgctcatg aatttcacgc agcgcacgat
    11881 gcaccacatc aacaggaacc gccgggtgtt taccttccag cgcatcagca atgcctgcaa
    11941 ccagcgcttc aggcaacagc ccttcaagac cggattcgct gagctgctgc cctacctgca
    12001 aaccaatgcc gtagctcgct tgcgcttcaa tagtgtcaaa agtcggggtg gccattattt
    12061 ttccttcatc ggatatcaaa aaagtagcgg gcagcataac agccacgctt cttctggtaa
    12121 aactttgtct cagggaggat gacaaatcgc agggaaaaag aaacaataga ttatccgtat
    12181 tgatgtcacg aaagcggata gcactaccag tatcatagcg ttagccatct atactctatg
    12241 attaaggaac gagatgcgga gcaggaggta aaccatgccc gggcgctttg aattaaaacc
    12301 aaccctggcg aaaatctggc acgcgccgga taattttcgc atcatggagc cgctgccgcc
    12361 tatgcatcgt cgtggcatta tcattgccgc tatcgtgctg gtgatcggct tcctgctgcc
    12421 cgccagcgag accagcgact cgcctgtcgt cacgcgggaa gcgcaattgg atctgcaatc
    12481 gcaatcacag ccgccgacgg aggcccagct tcaggcgcaa ctggtcgcgc cgcaaaacga
    12541 tccggatcag gtggcgcccg ttgcgtcgga acctatccag gaaggccagc cggaagaaca
    12601 aaaccagccg cagacgcagc ctttccagca ggatagcggc atcggtcaac aatggcgctc
    12661 gtaccgggta gagcctggta aaactctggc gcaactgttc cgtgaccacg gactgccccc
    12721 gacagacgtt tatgcaatgg cgcaggtaga aggcgctggc aagccgctga gtaacctcaa
    12781 aaatggtcaa atgattaaaa ttcgccagaa tgccagcggg gtggtgacag gtttaacgat
    12841 agatggcgat aacggtcaac aggtgctgtt tacgcgtcag cctgacggca gttttattcg
    12901 cgcacagtaa cgccggctgc gccttacccc gtctataccc tattcgttca ggtgaagcat
    12961 taccgcttca ccttattcac ccaccaaatc cccgaacaca ccagcaccag cgcaatcatg
    13021 tatttccact ccaatatatt ctcgccgaga aaaatagccg aaagagccgc gccagaaacc
    13081 gggatcagaa agttaaacgg cgcaatcatc cccacgcgat tatatttgag taaaatgttc
    13141 catagcgcaa aagcgaccga cgagagcagc gtcaggtaga ctaaaatcgc caccgacgag
    13201 aagccatgta tcgtcagcgt accgccaaaa acgtaaccgc caatgaccag taccagaccg
    13261 ccaatcccca attgatagcc agtcatgacc atcggatcga ccgtctgcga gagacgtttg
    13321 ccatacaatg tggccgcaga aagaataaac gcagccagca ccacggagcc ttctcccggc
    13381 agattaaagc tgaaatccag gccgttgctg acgttcacca ccatgacgcc cgcaaagccc
    13441 agaatacagc cgagcgtttt gttgtagctc aatcggtcgt tctgataaat aaagtgcgcc
    13501 agcaatacgc tgaagaatgt gcctgtcgcg ttcatgattg agcctttcac gccggaggtg
    13561 aacgcaaggc cgatatagaa aaagagatat tgcagcgacg tctgggtcag acctagtaac
    13621 gttaactgag caaactggcg cggacgaaac cgaccaatcg gtttacgctg aagcagcgcg
    13681 aacagtagta gcaacccacc cgcaaacaaa aaacgataac cagcaaaaac aattttagaa
    13741 gggatatcgt cggtggctat ctgaaagagg tcataaccgc ttttgatggc tggataagcg
    13801 ctgccccata gcaggcaaca aaatgcggca cacacataaa cgacgttttt gcgggcaaac
    13861 ggggaggcct ggcgttgggt atccattctt tcaccaagaa attaaaataa tgttttattt
    13921 ttaattatcg cgaaaagagg gggagatagc cagtcgaaaa gcgatggagt taaaaaagca
    13981 aaacgccggc gctgggccga cgtttcgttg ctagcaaaaa cgagaatgac tgattactca
    14041 gcaaccacgt tgatgataac ttttgcgaat acttcgctgt gaacctggaa gttcacttcg
    14101 tgttcgccag tggtacgcag aacgccgttc ggcagacgaa cttcgctctt agccacgtca
    14161 acgccagctg cagtcacagc gtcagcgatg tcgcgagtac cgatggaacc gaacagttta
    14221 ccttcgtcgc ctgctttaga cgcgatagta acggtttcca gggcgttgat tttctctgcg
    14281 cgtgcatttg cagcagccag aacgtcagcc agtttagctt ccagttcagc gcgacgtgct
    14341 tcgaagtatt caacgttttt cttggtagcc ggaacagctt taccctgtgg taccaggaag
    14401 ttacgagcat agcccgcttt aacgttaacc tgatcaccca ggctacccag gtttgctact
    14461 ttatcaagca gaataacttg cattacctta tcctctcaaa gtcgtattaa tggaccgtga
    14521 ccgattactg atggcgatca gtgtacggca gcagagacag gtagcgagcg cgtttgatag
    14581 cgcgagccag ctgacgctgg tattttgcac gggtaccggt gatacggctt gggacaatct
    14641 taccgctttc ggtgatgtag tttttcagcg tagcgatatc tttatagtcg atctcttgaa
    14701 cgccttccgc ggtgaaacgg cagaacttgc gacgacggaa ataacgtgcc atatggctag
    14761 tctccagaat ctatcaattc aatctgctcg gcatgcagaa ccattttgct cagaccgttc
    14821 tttgccttgt ggcaagaaat aaacccctga acggttatgc ggctgccgac cgttatactg
    14881 tgagtaatgg cctggttttc gtgtccgcta acaataacgg gcatttggca ccacgcctgc
    14941 cggtgaaagc cggcttcctc ttgcacagaa cgatgctcaa gcacgaactg gcaatgcgga
    15001 attcctgatg gactgacctt tcgaaggggg gccctgcaca cggtgccgga caacgtcaga
    15061 cggttggtca tcagaaatta ctcttcagaa tccccagctt cagcatcatc tgcggtttcg
    15121 ttagcgaaat catcgcgacg ctcacggcgc tcgtctttcg ctttaaccat cggagatgct
    15181 tcggtaacag cgtgcttagt acgcataacc atgctgcgga taacggcatc gttgaagcgg
    15241 aaggtagttt ccagctcatc gatcacttcc tgcggcgctt caacgttcat cagaacgtag
    15301 tgcgctttgt gcagtttgtt gatcgggtaa gccagctgac ggcggcccca gtcttccaga
    15361 cggtggatct tgccttctgc gccagtgatg gcagcagagt aacgctcgat catacccgga
    15421 acctgttcgc tctggtcagg atggaccata aaaacgattt cgtaatgacg catcgaattg
    15481 ctccttacgg attattcagc ctcctgtctg ggtcagccgc ggcccatgga ggcaaggaac
    15541 gtgttaaagg tcggctgaaa aatgacgcgt tataatactg gcgcctgcgg gcaaactcaa
    15601 ggtgattgta caattattta tcgtgccgaa cgtaacgcct gtcccgtcac attttgctgc
    15661 tgagatatta acttcatatc gcatgccact ataaacggcc tgttgcggca gaaaaattga
    15721 cactgtggtc agcgtacttt tttgccacac agggtttctt aaacatagcg gcatacatca
    15781 acgggttgtt aatcaggtaa aaaacgacaa tgcgataatt ttttgaacaa cagcatcaga
    15841 aaaggtcgcc atctctgcgg ctggttatgg ttaaaattaa accagaagcg attcactaaa
    15901 gggggatatc gccaaccaga ccgcgctgct gaggaggtac tctatgcgag cccggataat
    15961 gttatttctg gctgcgcttt tgcctggcat aacggcaacg gcagccatcg agttaaataa
    16021 tcaccaggcc acaaatatgg atgatgtgcg cagcttaggc gtgatctaca tcaaccataa
    16081 cttcgccacg gaaagcgaag ccaatctggc gctgaatgac gaggccgacg cgcgaaacgc
    16141 aatgtattat cacgccatac ttatccggga accgggtagc aacggcaaca tacacgccag
    16201 cgcgaatatt tatcgctaac atcaggaaaa ccaacgaaaa agccatagtt gatttgcccc
    16261 cctgaacagg gggctttttt cgcggaaaga tggctccgga attagacctg tgacatcccg
    16321 ataatattca cattccggag ctcatacttc acttctgccc gtaatacgca ttcgggccat
    16381 gcttacgcat gaagtgttta ttcatcagat aatcgtcgat ggggttgagg ccagggttaa
    16441 tgccgcgcgc aatccacgcc attctcgcca cttcttccat gacgaccgcg ttatgtaccg
    16501 catcgtgcgc atctttcccc caggcgaacg gcccgtgttg atacacgaca atgcctggcg
    16561 tatgcagcgg ttccacctcg cccagcgttt cgatgatcac cttgccggtg ttcagctcgt
    16621 actcgccctg cacttcttct tcgcttaacg ccctggtaca aggaatatcg ccaaagaaat
    16681 agtccgcgtg cgtggtaccg agcgctggaa tagccatccc cgcctgcgcc catgccgtgg
    16741 cgtgggttga atgggtatga acgacgccgc caagcgacgg atagcgttga tacagcgcca
    16801 gatgggtagc ggtatcggaa gaaggacgat aacgaccctc caccactttg ccatccatat
    16861 ccaccaccac catgtcatct accttcatgg tttcataggc gacaccgctt ggcttaatca
    16921 ccaccagccc gcgttcgcga tcgatagcgc tgacgttgcc ccaggtaaac gtcaccagtc
    16981 cataacgggg caaatccatg ttagcgtcaa atacctgctg cttgagcttt tgcattatgc
    17041 cgcctccacc atgcctgctt tggccatgcg cgctttcacc cagtcacgcg ctttcgctac
    17101 ctctgccgcc gggttctctg ctgtttcgct ccacatctca atcagatagg gcccgcaata
    17161 gccactctgt ttgagcgttt cgaagcagcg ttcgaaatcg acaacgcctt cgccaaacgg
    17221 cacatttttg aacacgccgg gtttagtatc tttgacgtgt accgcgacga tatgcccgat
    17281 tcccgcctgt agctccatct gtacgtcgtt atcccaggca gacagattgc cgatatccgg
    17341 atagagctga aagcacgggt tattgaggta gtgagcatag cctagcgctt tactgatgga
    17401 attcatcaat gggtaatcca tgatctccat cgccagcgtc acctgggcgc ggctggccat
    17461 atcaacgctc tcttttaacc catcgcggaa gcggcaacgc gtttcgtcgt tggcctgctg
    17521 atagtaaacg tcgtaccccg ccagttgaat gacgcgaatc ccgacgtcct gcgcaaactg
    17581 aatcgcttta cgcataatct ccagcccctg cgcccgtacc gcgtcatctt cgctaccgag
    17641 cggaaaacga cgatgcgcgc tcagacacat ggacggcaca cgcacgccgg tttcagcaac
    17701 cgcgctcacc agcgccaggc gctgctcgcg actccagtcg agccgcgcca gtcgggcgtc
    17761 ggtctcgtcc accgacattt caacgaagtc aaaacccagc gttttcgcca gccgcaggcg
    17821 ttccagccag cactccccgg cagggagcgc tttttcatag atgccgagcg gaatttgttt
    17881 cgacagcata gccgctcctt agccccacag ttgggcaatg gagcgtttga actgccgtgc
    17941 ggcttctacc ggcgattcag catcgcgaat gctgcggcca gcaataaaga catggatcgg
    18001 aatgcctttg aacagcggca ggtcttccag cgccagtccg ccggtcacgg tcactttaaa
    18061 gcccatatcg gacagccgtt taatcgcagt aatatccgct tcaccccacg ccacgcctgc
    18121 ggcctgcgcg tcgcagctgc ggtggtaaac cacttgctga atgcccgcat cgcgccactg
    18181 ctgcgcctgt tcccaggtcc agtaaccggt cagttcaatc tgcacgtcgc cgttaaactc
    18241 ttttgccaca tccagcgcgc ctttcgcggt gttgatatcc gcacagcaaa tcacggtcac
    18301 ccagtccgcg ttggcttcga agcacatacg agaaaggatt ttgcccgcat cggcaatttt
    18361 ggcatctgcc agcacgattt tgtgcgggta aagcgctttc agatcgcgaa ccgcacgcac
    18421 gccttcgccc acgcacagaa tggtgcccac ttcgataatg tcgacttctt cggcaatcag
    18481 gcgagtggtt tcgtaggcgc tatccatagt ctggttgtcc agcgcgactt gcaacatcgg
    18541 taatgacatg ttcaattcct tcttaagctg ccgcgttggt gcggtcaatg agatccagga
    18601 cttcctgcgc ggtacggcag gcgcgtaaac ggtcaaaatt ggcttcgtct tcaaacaggt
    18661 tgacgatctg catgatgccc acttcctggt gagtgttggc atcaaccgcc gccatagtga
    18721 tcagaatatc gaccgggtcg ttatcttcgt ggttgaactc cagcggcttt ttcagcgtca
    18781 ccagtgagaa accggttttc ttcacgccct cttccggacg cccgtgcggc attaccagcc
    18841 ccggagcgat aacgaaataa gggccgaact gttccacgcc atcgagaatc gcctggtagt
    18901 aacgcggctc gacaacgtct gccgccacca gcaaatccac accaattttt acggcttcct
    18961 gccaggtatt agcttcagcc tgcaagcgga tagaattatt ctccgccagc gaatcacgta
    19021 atttcatgtt gcgtccttac ttcacgtcct gtggaaaatg cgctttgatc acttccagca
    19081 atttcgggcc gaagtctgcg ggcgatagca tgttgcgcac gccaaccaca tatttgttgc
    19141 ccgtcacggt gatttcgcct gcaatgtgtg tggaagcgat gatgatatcc gcgccgctca
    19201 actcgctttt gtactcgcca accgcgcagc tgtttaccgt gtggtcgata ttggattggg
    19261 ttaaaactgg tccactttca ttttcatgat catggaactg ccctgtccgt tgccacacac
    19321 agccagaata cgtacggtca taatcaaaac tccttattaa gcagactgtt ctgccagttg
    19381 tttttctgca tcttcttctg cgcgcagtgc gcggccagcg aagaacatat aagccagtgc
    19441 aattacaatg atgacggcca taaaggcgat accgatggag aagaagccct gcatcatcgg
    19501 cggcgccaga atcgaccagt ccgccatacc catccaggcg ctcatccccg tgagtttcac
    19561 cgcccagacg caaccaaaga tttcaatcat ccccatcacc agacaaattt tcagcgccgc
    19621 acgccagccg ccgaagtggt tagcgaacac gccgatagtg gcgttagaga agaacatcgg
    19681 gataaagcca ggaataatca ggatcgagga gccgcaggca accaggatgc caaccgcaat
    19741 cagctgaccg atggtgcccc acataaagcc ccagactacg gcgttcggcg cgaagctata
    19801 gatagccgca cagtcaatcg ccagaaccgc acctgggatc aggcgctggg agataccgtt
    19861 aaacgcttca gagagttccg ccacaaacat gcgcacgccc tgagtgatga tgaagatcgc
    19921 caccgcaaag gagaaaccgg tttgcaggat gtagaccgtc cagtgcactt tgcccgccat
    19981 cgcctgcacg gtgtcgatac cgaaggagag cagaatggca ccaaagaaga tggtcattac
    20041 aatcgccgta gaaacgatgt tgtcgtggaa gatattcagc cagcccggca atttgaggtc
    20101 ttcaacgctt tcctcttttt tgcccaggaa cggcgcgact ttataggcaa tccaggaagc
    20161 aaactgctgc tggtgaccaa tggagaaacc gcagccgtcc gtcacttctt gggtgggctt
    20221 atacatcatg ttggaagtga tgccccagta cagggaaacc agtatcgccg tgcagataat
    20281 ggtggtccac atggaatagc cgaagatata gaaagagacc gcaatcagcc ccgcctgctg
    20341 gaacatgatg tgcccggtca acatgatggt gcgaataccg gtaatgcgtc gcaataagac
    20401 gtaacaaata ttcagcgcca gcgcgagcaa caccgcgtag cctacccaac tatacgcatc
    20461 gcccatccgt tcgatcgttg ccatcatcga agcataggta tcggaaatcg cgccgttgat
    20521 accgtagacc tcagacattt tcgccaccac cggtttaaag gtgctggtca gaatgccgga
    20581 cccggcctgt agcagcatga agccaatgat ggttttgatc gtccctttga tgatcacgct
    20641 gacgcttttg cgcaacagga tatagcccag gcaggtcaca atacccagta atagcggggc
    20701 attagtcatt acctgattaa agaaaatggt aaagatgttg tagaggatct ccataacgat
    20761 ctccggcaga taaggttgct gagtcacagg cgctcaggat aatgtccctt cactttaatt
    20821 ttcaaaagta atcacaacaa gattaaattt gattaaatgt gacgtagcgc
//
LOCUS       DAJVBX010000065        20818 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.065, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000065 DAJVBX010000000
VERSION     DAJVBX010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 20818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20818
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.065"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            156..1487
                     /gene="cadB"
                     /locus_tag="OPV72_002062"
     CDS             156..1487
                     /gene="cadB"
                     /locus_tag="OPV72_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadaverine/lysine antiporter"
                     /protein_id="HCR9914361.1"
                     /translation="MSSVKKIGLFACTGVVAGNMMGSGIALLPANLASIGGIAIWGWV
                     ISIIGAMSLAYVYARLATKNPQQGGPIAYAGEISPAFGFQTGVLYYHANWIGNLAIGI
                     TAVSYLSTFFPALNNPIPAGIACIAIVWLFTFINMLGGAWVSRLTTIGLFLVLIPVVL
                     TAVAGWHWFAIATYHANWNTSTTTDSHAIVKSILLCLWAFVGVESAAVSTGMVKNPKR
                     TVPLATMLGTALAGIIYIAATQVIAGMFPASVMASSGAPFAISTSTILGGWAAPLVSA
                     FTAFACLTSLGSWMMLVGQAGVRAANDGNFPKIYGEMDKNGIPKKGLLLAAVKMTALM
                     ILITIMNSSGGKASDLFGELTGIAVLLTMLPYFYSCVDLIRFEGFNIRNSVSLICSVL
                     GCAFCFIALMGASSFELSGTFIVSLIILMFYGRKMHQRQNNDSDNNTAEAL"
     gene            1570..3714
                     /gene="cadA"
                     /locus_tag="OPV72_002063"
     CDS             1570..3714
                     /gene="cadA"
                     /locus_tag="OPV72_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine decarboxylase CadA"
                     /protein_id="HCR9914362.1"
                     /translation="MNVIAIMNHMGVYFKEEPIRELHRALEGLNFRIVYPNDREDLLK
                     LIENNSRLCGVIFDWDKYNLELCEEISKLNEYMPLYAFANSYSTLDVSLNDLRMQVRF
                     FEYALGAAADIAAKIRQNTDEYIDNILPPLTKALFKYVREGKYTFCTPGHMGGTAFQK
                     SPVGSIFYDFFGPNTMKSDISISVSELGSLLDHSGPHKEAEEYIARVFNAERSYMVTN
                     GTSTANKIVGMYSAPAGSTVLIDRNCHKSLTHLMMMSDITPIYFRPTRNAYGILGGIP
                     QSEFQHATIAKRVKETPNATWPVHAVITNSTYDGLLYNTDYIKKTLDVKSIHFDSAWV
                     PYTNFSPIYQGKCGMSGDRVEGKIIYETQSTHKLLAAFSQASMIHVKGDINEETFNEA
                     YMMHTTTSPHYGIVASTETAAAMMKGNAGKRLINGSIERAIKFRKEIKRLKSESDGWF
                     FDVWQPEHIDGAECWPLRSDSAWHGFKNIDNEHMYLDPIKVTILTPGMKKDGTMDEFG
                     IPASLVAKYLDERGIIVEKTGPYNLLFLFSIGIDKTKALSLLRALTEFKRAFDLNLRV
                     KNILPALYREAPEFYENMRIQELAQNIHKLVEHHNLPDLMYRAFEVLPKMVMTPYTAF
                     QKELHGETEEVYLEEMVGRVNANMILPYPPGVPLVMPGEMITEESRPVLEFLQMLCEI
                     GAHYPGFETDIHGAYRQADGRYTVKVLKENTK"
     gene            3770..5230
                     /gene="dtpD"
                     /locus_tag="OPV72_002064"
     CDS             3770..5230
                     /gene="dtpD"
                     /locus_tag="OPV72_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide permease DtpD"
                     /protein_id="HCR9914363.1"
                     /translation="MKTPSQPRAIFYIVAIQIWEYFSFYGMRALLILYLTHQLGFNDS
                     HAINLFSAYASLVYVTPILGGWLADRLLGNRVAVITGALLMTLGHVVLGLESDSTLSL
                     YAALAIIICGYGLFKSNISCLLGELYAPDDNRRDGGFSLLYAAGNIGSIAAPIACGLA
                     AQWYGWHVGFALAGVGMFIGLLIFLSGHRHFQQTRGVNRPALRAVKFALPTWGWLVLM
                     LCIAPVFFTLLLENNWSGYVLAIVCVFAAQLIARIMVKFPEHRRALWQIVLLMITGTL
                     FWVLAQQGGSSISLFIDRFVNRHWLNMTVPTALFQSVNAIAVMAAGVVLAWLSSPKES
                     ARSVLRVWLKFAVGLILMGGGFMLLALNAHQARLDGQASMGMMIAGLALMGFAELFID
                     PVAMAQITRLNLPGVTGVLTGIYMLATGAIANWLAGVVAQQTTESQISDTAVAAYGHF
                     FSQMSEWTLSCVALIVAIVGLRWICTRTTSALPQGD"
     gene            complement(5279..5617)
                     /gene="glnB"
                     /locus_tag="OPV72_002065"
     CDS             complement(5279..5617)
                     /gene="glnB"
                     /locus_tag="OPV72_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017373484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen regulatory protein P-II"
                     /protein_id="HCR9914364.1"
                     /translation="MKKIDAIIKPFKLDDVREALAEVGITGMTVTEVKGFGRQKGHTE
                     LYRGAEYMVDFLPKVKIEIVVPDDIVDTCVDTIIRTAQTGKIGDGKIFVFDVARVIRI
                     RTGEEDDAAI"
     gene            complement(5694..7031)
                     /gene="glrR"
                     /locus_tag="OPV72_002066"
     CDS             complement(5694..7031)
                     /gene="glrR"
                     /locus_tag="OPV72_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator GlrR"
                     /protein_id="HCR9914365.1"
                     /translation="MISRKPAHLLLVDDDPGLLKLLGMRLTSEGYSVVTAESGQEGLR
                     VLHREKVDLVISDLRMDEMDGMQLFTEIQKVQPGMPVIILTAHGSIPDAVAATQKGVF
                     SFLTKPIDRDALYKAIDEALEQSAPATDDSWRNAIVTRSPLMLRLLEQARMVAQSDVS
                     VLINGQSGTGKEIFAQAIHNASPRNNKPFVAINCGALPEQLLESELFGHARGAFTGAV
                     SNREGLFQAAEGGTLFLDEIGDMPAPLQVKLLRVLQERKVRPLGSNRDIDIDVRIISA
                     THRDLPKAMARGEFREDLYYRLNVVSLKIPALAERTEDIPLLANHLLRQSAQRHKPFV
                     RAFSTDAMKRLMTASWPGNVRQLVNVIEQCVALTSSPVISDALVEQALEGENTALPTF
                     AEARNQFELNYLRKLLQITKGNVTHAARMAGRNRTEFYKLLSRHELDANDFKE"
     gene            complement(7028..7792)
                     /gene="qseG"
                     /locus_tag="OPV72_002067"
     CDS             complement(7028..7792)
                     /gene="qseG"
                     /locus_tag="OPV72_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system QseEF-associated
                     lipoprotein QseG"
                     /protein_id="HCR9914366.1"
                     /translation="MNLSLVRMSHVFVQTIKRCLLRWGIPVGISCLALTACVPHASQQ
                     LPGSAAQDTLPHYQLADYLPTACADIWSLRGQAVETNPLYWLRTIDCADRLMPVQSRA
                     EARSLTDDNWQNAFRRGILLADAKITPPERRAIVTRLEALSAQIPAQVRPVYQIWHDG
                     QALQLALSAERQRYSKLQQTSDSELDALRQQQQALQTQLDLTTRKLESLTDIERQLST
                     RKPAGNYNADTPHTNDKPATSEDGAAPSPSQDEVTP"
     gene            complement(7794..9224)
                     /gene="qseE"
                     /locus_tag="OPV72_002068"
     CDS             complement(7794..9224)
                     /gene="qseE"
                     /locus_tag="OPV72_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001676035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two component system sensor histidine kinase
                     QseE/GlrK"
                     /protein_id="HCR9914367.1"
                     /translation="MKRWSVFPRSLRQLVMLAFLLILLPLLVLAWQAWQSLNALSDQA
                     AVTNRSTLIDARRSEAMTNVALEMERSYRQYCVLDDPTLTKVYQSQRKRYSDMLDAHA
                     GVLPDDKLYQALRQDLNALAQLQCKDSGPEAAAAARLEAFANANTEMVQATRTVVYSR
                     GQQLQQEIAERGQFFGWQALVLFLVSLAMVLLFTRMIIGPVKGIERMINRLGEGRSLG
                     NTVTFTGPRELRSVGQRIIWLSERLAWLESQRHQFLRHLSHELKTPLASMREGTELLA
                     DQVVGPLTPEQKEVVDILDDSSRNLQKLIEQLLDYNRKLVDSATELEAVDIAPLVDMV
                     VSAHSLPARAKMMHTDVDLEAERCIAEPMLLMSVLDNLYSNAVHYGAESGNICIRSRS
                     QGSTVYIDVVNSGEPIPQTEREMIFEPFFQGSHQRKGAVKGSGLGLSIARDCIRRMQG
                     EIQLVDDKAQEVCFRISLPLPASDKH"
     gene            complement(9874..13761)
                     /gene="purL"
                     /locus_tag="OPV72_002069"
                     /gene_synonym="purI"
     CDS             complement(9874..13761)
                     /gene="purL"
                     /locus_tag="OPV72_002069"
                     /gene_synonym="purI"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HCR9914368.1"
                     /translation="MMEILRGSPALSAFRINKLLARFQAANLQVHNIYAEYVHFADLN
                     APLNDSEQAQLTRLLQYGPALSSHTLAGKLLLVTPRPGTISPWSSKATDIAHNCGLQQ
                     IDRLERGVAYYIEASTLTAEQWRQVAAELHDRMMETVFSSLTDAEKLFIHHQPAPVSS
                     VDLLGEGRQALIDANLRLGLALAEDEIDYLQEAFTKLGRNPNDIELYMFAQANSEHCR
                     HKIFNADWIIDGKPQPKSLFKMIKNTFETTPDYVLSAYKDNAAVMEGSAVGRYFADHN
                     TGRYDFHQEPAHILMKVETHNHPTAISPWPGAATGSGGEIRDEGATGRGAKPKAGLVG
                     FSVSNLRIPGFEQPWEEDFGKPERIVTALDIMTEGPLGGAAFNNEFGRPALTGYFRTY
                     EEKVNSHNGEELRGYHKPIMLAGGIGNIRADHVQKGEIVVGAKLIVLGGPAMNIGLGG
                     GAASSMASGQSDADLDFASVQRDNPEMERRCQEVIDRCWQLGDANPILFIHDVGAGGL
                     SNAMPELVSDGGRGGKFELRDILSDEPGMSPLEIWCNESQERYVLAVAADQLPLFDEL
                     CKRERAPYAVIGDATEEQHLSLHDNHFDNQPIDLPLDVLLGKTPKMTRDVQTLKAKGD
                     ALNRADITIADAVNRVLHLPTVAEKTFLVTIGDRTVTGMVARDQMVGPWQVPVADCAV
                     TTASLDSYYGEAMSIGERAPVALLDFAASARLAVGEALTNIAATQIGDIKRIKLSANW
                     MAAAGHPGEDAGLYDAVKAVGEELCPQLGLTIPVGKDSMSMKTRWQEGNEQREMTSPL
                     SLVISAFARVEDVRHTLTPQLSTEDNALLLIDLGKGHNALGATALAQVYRQLGDKPAD
                     VRDVAQLKGFYDAMQVLVAARKLLAWHDRSDGGLLVTLAEMAFAGHCGVQVDIAALGD
                     DHLAALFNEELGGVIQVRAEDRDAVETLLAQYGLADCVHYLGQALAGDRFVITANDRT
                     VFSESRTTLRVWWAETTWQMQRLRDNPQCADQEHEAKANDADPGLNVKLSFDINEDIA
                     APYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLGGRIGLGNFHAL
                     VACGGFSYGDVLGAGEGWAKSILFNHRVRDEFETFFHRPQTLALGVCNGCQMMSNLRE
                     LIPGSELWPRFVRNHSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGRVEVR
                     DDAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTENGRVTIMMPHPE
                     RVFRTVANSWHPENWGEDSPWMRIFRNARKQLG"
     gene            13786..14016
                     /locus_tag="OPV72_002070"
     CDS             13786..14016
                     /locus_tag="OPV72_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001669324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914369.1"
                     /translation="MCARGETAAIIKNLTRRRNRLRRNKITAFSCHTVRLSLRISCQL
                     AHCYAKCRSLVTYLLQQNIFFSPRQRTIQRIN"
     gene            14017..15444
                     /gene="mltF"
                     /locus_tag="OPV72_002071"
     CDS             14017..15444
                     /gene="mltF"
                     /locus_tag="OPV72_002071"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000734247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane-bound lytic murein transglycosylase
                     MltF"
                     /protein_id="HCR9914370.1"
                     /translation="MKKLKINYLFIGILTLLLAAALWPSIPWFGKTENHIAAIQARGV
                     LRVSTIDSPLTYSVINGKKYGLDYELAQQFANYLGVKLKVTVRQNISQLFDDLDNGNA
                     DLLAAGLVYDSARVKNYQPGPMYYSVSQQLVYRVGQYRPRSLATVNENQLTIAPGHVV
                     VNDLQRLKETKFPDLSWKVDDKKGSTTLLEEVISGKLDYTIADSVAISLFQRVHPELA
                     VALDVTDEQPVTWFSRLDDDNTLSAALLDFFNSINEDGSLARIEEKYLGHGDDFDYVD
                     TRSFLRAVDNVLPELEPLFKKYAKEIDWRLLAAISYQESHWDPLATSPTGVRGLMMLT
                     KNTAQSLGLTDRTDAEQSISGGARYLEDMMAKVPETVPEDERIWFALAAYNMGYAHML
                     DARSLTVKTKGNPDSWTDVKQRLPLLSQKPYYSKLTYGYARGHEAYAYVENIRKYQIS
                     LVGYLQEKEKQEAEAMKLAQDYPAV"
     gene            complement(15612..16163)
                     /gene="tadA"
                     /locus_tag="OPV72_002072"
     CDS             complement(15612..16163)
                     /gene="tadA"
                     /locus_tag="OPV72_002072"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HCR9914371.1"
                     /translation="MPPAFITGVTSLSDVELDHEYWMRHALTLAKRAWDEREVPVGAV
                     LVHNHRVIGEGWNRPIGRHDPTAHAEIMALRQGGLVLQNYRLLDTTLYVTLEPCVMCA
                     GAMVHSRIGRVVFGARDAKTGAAGSLIDVLHHPGMNHRVEIIEGVLRDECATLLSDFF
                     RMRRQEIKALKKADRAEGAGPAV"
     gene            complement(16188..16823)
                     /gene="yfhb"
                     /locus_tag="OPV72_002073"
     CDS             complement(16188..16823)
                     /gene="yfhb"
                     /locus_tag="OPV72_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase C"
                     /protein_id="HCR9914372.1"
                     /translation="MVSHERRVVFFDLDGTLYQQDMFGSFLRYLLRRQPLNALLVLPL
                     LPIIGIGLLVKGRAARWPMSLLLWGCTFGHSETRLQAHQADFVRWFRANVTAFPVVQE
                     RLTTYLLSSDADIWLITGSPQSLVEQVYFDTPWLPRVNLIASQMARRYGGWVLTVRCL
                     GHEKVAQLERKIGTPLRLYSGYSDSKQDNPLLYFCQHRWRVTPHGELQQLE"
     gene            complement(16827..18188)
                     /locus_tag="OPV72_002074"
     CDS             complement(16827..18188)
                     /locus_tag="OPV72_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCR9914373.1"
                     /translation="MDKTAALASDILRGIGGEQNILRLENCMTRVRVEVQDDSQLDIP
                     RLKALPGVSGYVKQGEQHQLIVGPGKAAQVVDAMRVQIAAGGVKPDDAMARTKSEAKA
                     KYKAPMSDALRKLANVFIPLIPAFIASGLITGIINILKRPDIVGDVAVHYPNLLGLMG
                     IFGSAVFAIMNILVGVNTAKVFGGSQALGGVMAGILSSPQLAQITLFGEALQPGRGGV
                     IAVLLVVALMCWIERQFRKLLPGSLELILNPLLTTVITGAVAIVALQPLGGWISDAIA
                     HGASWAIDRGGFLVGAVLAGTFLPLVLIGLHQGLVPIHVELVQAHGYNALFPILAMAG
                     VGQIGAAIAVLMKTRNARLKKVIKGALPVGLLGIGEPLIFGVTLPLGKPFIGACLGGA
                     VGGALISYWKVATVITFGISGLPLALTIVAGKVLFYLLGYLIAVIAGFIFTWLLGFND
                     PEE"
     gene            complement(18199..19092)
                     /gene="murQ"
                     /locus_tag="OPV72_002075"
     CDS             complement(18199..19092)
                     /gene="murQ"
                     /locus_tag="OPV72_002075"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HCR9914374.1"
                     /translation="MNLGALVSETRNPQTMDLDALSTPELVKRFNEQDTLVAEAVKAT
                     LPDVARAVDAAAAALKSGGRIIYMGAGTSGRLGVLDASECPPTFGVPHGLVVGLIAGG
                     PGALLKAVEGAEDSQQAGEDDLVALNLQEQDLVVGLAASGRTPYVIGGLRYARQSGCT
                     TVAVSCNPDSPIAREANIAISPVVGPEALTGSTRLKSGTAQKMVLNMISTGAMVKFGK
                     VYQNLMVDMKATNVKLVDRACRMVVEATGIGREEAETLLKQTDFEVKPAILMALTGLD
                     AAAAREKLAAHQGFLRAALEH"
     gene            19208..20056
                     /locus_tag="OPV72_002076"
     CDS             19208..20056
                     /locus_tag="OPV72_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCR9914375.1"
                     /translation="MNCLIRIRQRYPDLAQSDRKLADYLLAQPDTARHLSSQQLAAEA
                     GVSQSSVVKFAQKLGFKGFPALKLAISEALASNPNPHSVPVHNQIRGDDPMRLVGEKL
                     IKENVAAMHATLDVNSEEKLLESVTMLRHARRIVITGIGASGLVAQNFAWKLLKIGIN
                     AVVERDMHALLATVQALAPEDLLLAISYSGERRELNLAADETLRAGAKILAITGFSPN
                     ALQQRATRCLYTIAEEQATRSAAISSTHAQMMLTDLLFMALVQQDLERAPERIRHSEA
                     LVKKLV"
     gene            complement(20095..>20818)
                     /locus_tag="OPV72_002077"
     CDS             complement(20095..>20818)
                     /locus_tag="OPV72_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HCR9914376.1"
                     /translation="QGEFELVILFTKAMQLDSMLQRIKPLLPAAKVVMILSNGLGNIE
                     TLEKYVDRQKIYAGVTLWSSELEGAGHIMATGTGTIELQPIASQDSAQEAKVIATLNS
                     AGLNAEISPDVLLSIWKKAAFNSVMNTYCALLDCNVGGFGQRPGALDLAQAVVDEFVL
                     VAASQNIPLTEQMVMNTVKKVFDPRESGHHYPSMHQDLHKGRLTEIDYLNGAIARIGA
                     QNNIAVPVNTLLTQLIHAKEAQ"
BASE COUNT         4763 a         5945 c         5359 g         4751 t
ORIGIN      
        1 atcaatctat cagttttttc atgtttgtgt ttatttcact ttttctttag gacttatctc
       61 aacccattcg ttaatcttgt cgacagttga acgggcacgc agcatatatg aagcataagc
      121 ccggttctta aaaatacagc tcaggagaaa tgaacatgag ttctgtcaaa aagatcgggc
      181 tatttgcctg tactggcgtc gttgccggta atatgatggg gagcgggatt gcattattac
      241 ccgccaacct tgccagtatt ggtggcattg ccatctgggg ctgggtaatt tctattattg
      301 gggcaatgtc gctggcttat gtttatgcga ggctggcaac caaaaacccg caacagggtg
      361 gccctatcgc ttatgctggg gaaatatctc cggcgtttgg tttccagacc ggcgttcttt
      421 attatcacgc aaactggatt ggtaacttag ccatcggtat taccgcggtt tcttatcttt
      481 ctacgttctt cccggcatta aataatccaa taccggcagg tattgcctgt attgctatcg
      541 tctggctgtt cacctttatt aatatgctgg gcggggcctg ggtcagccgc ttgacaacga
      601 ttggcctgtt tctggtgctg atcccggtag tcttgaccgc agtcgccggc tggcattggt
      661 tcgctatcgc gacctatcac gcgaactgga acacgtctac gacgaccgac tctcacgcca
      721 ttgttaaaag tattctgctc tgcctgtggg cgttcgttgg cgttgagtct gccgccgtca
      781 gcaccggcat ggtgaaaaac ccgaaacgca ccgtaccgct ggcaaccatg ctgggtaccg
      841 cgctggcagg catcatctat atcgccgcga ctcaggttat cgccgggatg ttcccagctt
      901 ccgttatggc ctcttccggc gcgccgttcg ctatcagtac ctccacgatt ctgggtggct
      961 gggctgcgcc gctggtttcc gcctttaccg ctttcgcctg cctgacgtct ctgggctcct
     1021 ggatgatgct ggtcggccag gctggggttc gcgccgccaa cgacggcaac ttcccgaaaa
     1081 tttacggtga aatggataaa aacggtattc cgaaaaaagg tctgctgttg gctgcggtga
     1141 aaatgacggc gctgatgatt ctgatcacca tcatgaactc cagcggcggt aaagcgtccg
     1201 acctgttcgg cgaactgacc gggattgccg tactgcttac catgctgccg tacttctact
     1261 cttgtgttga cctgattcgt ttcgaagggt tcaacatccg taactcggta agcctgattt
     1321 gttctgtact gggctgcgca ttttgcttca tcgcactgat gggcgccagc tccttcgaac
     1381 tctccggcac ctttatcgtc agtctgatca tcctgatgtt ctacggtcgc aaaatgcacc
     1441 agcgccagaa caacgacagc gacaacaata cggctgaagc gctttaaccg ctaactcctt
     1501 tttctcaaag cccctttcgt cacctgctat agcgtagcgg gaggggccca ctttaccagg
     1561 aacaagacta tgaacgttat tgctatcatg aaccacatgg gcgtctactt taaagaagag
     1621 cctattcgtg aactgcatcg tgcactggaa ggtttaaatt tccgtatcgt ctatccaaac
     1681 gaccgagaag acctgctgaa gctgattgaa aataactccc gcctttgcgg cgtcattttc
     1741 gactgggata aatataacct tgagctttgc gaagagatta gcaagctgaa cgagtatatg
     1801 ccgctgtatg ccttcgccaa cagctactct acgctggacg tcagcctcaa cgatctgaga
     1861 atgcaggttc gcttctttga atatgcttta ggcgccgcag ccgatatcgc ggcgaaaatt
     1921 cgccagaata ccgatgaata catcgacaat attctgccgc cgctgacaaa agcactgttc
     1981 aaatatgtgc gcgaagggaa atacactttc tgtacgcctg gccacatggg cggtactgct
     2041 ttccagaaaa gccccgtcgg cagcatcttt tatgatttct tcggcccgaa cacgatgaaa
     2101 tccgatattt cgatttccgt ttccgaactg ggttcgctgc tggaccactc cggcccgcat
     2161 aaagaagcgg aagagtatat cgcccgcgtc tttaacgccg aacgtagcta catggtgacg
     2221 aacggcacct ctacggcgaa caaaatcgtc ggtatgtact ccgcgccggc aggcagcacg
     2281 gtactgattg accgtaactg ccataaatcg ctgacccatc tgatgatgat gagcgacatt
     2341 acgccgattt atttccgccc aacccgtaac gcctacggta ttcttggcgg tattccgcaa
     2401 agcgagttcc agcacgccac tatcgctaaa cgggtaaaag agacgcctaa cgccacctgg
     2461 ccggtccatg ctgttattac taactcaacc tatgacggtc tgttgtataa cactgactac
     2521 atcaagaaaa ctctggatgt gaagtccatt cattttgact ccgcctgggt gccttacacc
     2581 aatttctccc ctatttatca gggtaaatgc ggtatgagcg gcgaccgtgt agaaggcaaa
     2641 atcatttatg aaacccagtc cacgcataaa ctgctggcgg cgttttcaca ggcatccatg
     2701 attcatgtta aaggcgacat taacgaagaa acctttaacg aagcctacat gatgcatacc
     2761 accacttctc cgcactacgg tatcgtagcg tctactgaaa ccgcagcggc gatgatgaaa
     2821 ggtaatgcgg gtaaacgcct gattaacggc tctattgaac gtgcgattaa attccgtaaa
     2881 gaaattaaac gcctgaaaag cgaatctgac ggctggttct ttgacgtatg gcagccggaa
     2941 catatcgatg gagctgagtg ctggccgctg cgttcagata gcgcatggca tggcttcaaa
     3001 aatatcgata acgaacacat gtacctcgac ccgatcaaag tcactatcct gacgccgggg
     3061 atgaagaaag acggtacgat ggatgaattc ggtattccgg caagtctggt cgccaaatat
     3121 ctcgatgaac gcggcatcat cgtagaaaaa accggtccat acaacctgct gttcctgttc
     3181 agcattggta tcgacaaaac caaagctctg agcctgctgc gcgcgctcac tgaatttaaa
     3241 cgcgcctttg acctgaacct gcgcgtcaaa aacattctgc cggcactgta tcgcgaagcg
     3301 cctgagtttt atgaaaatat gcgcatccag gaactggcgc agaatattca taaactggtc
     3361 gaacatcata atctgccgga cttaatgtac cgtgcgtttg aagtgctgcc gaaaatggtg
     3421 atgacgccgt atactgcgtt ccagaaagag ctgcatggcg aaacggaaga ggtgtatctt
     3481 gaagagatgg ttggacgcgt caacgccaac atgatccttc cttaccctcc gggagtgccg
     3541 ctggtgatgc ctggtgaaat gatcaccgag gaaagccgtc cggtactgga attcctgcaa
     3601 atgctgtgcg aaatcggcgc tcactatccg ggcttcgaaa ccgatatcca cggcgcctat
     3661 cgtcaggctg acggacgtta caccgttaag gtgctgaaag aaaatacgaa ataagtacca
     3721 aagggaagtg gcttgccact tccctttttt cacgcagcaa ggagacttta tgaaaacacc
     3781 ctcacaaccg cgcgcgattt tttacatcgt ggcgattcaa atttgggaat acttcagctt
     3841 ttacggcatg cgtgccttac tcatccttta tcttacccac cagcttggtt ttaatgacag
     3901 ccacgcgatc aacctcttca gcgcctacgc ctctttagtt tacgttaccc ctattcttgg
     3961 cggctggctt gccgaccgcc tgcttggcaa ccgcgtggcg gttatcaccg gcgccttatt
     4021 gatgacgctg ggtcatgtgg tattgggctt agaatctgat tcaacgctga gtttatatgc
     4081 ggcgctggcc attattatct gcggctacgg cttgtttaaa tccaatatta gctgtctgct
     4141 gggcgaactt tacgcccctg atgacaaccg ccgcgacggg ggattctcgc tgctctacgc
     4201 cgccgggaat attggatcga tagccgcgcc gatcgcctgt ggtctggcgg cgcagtggta
     4261 tggctggcat gtcggctttg cgctggcggg cgtcggaatg ttcatcggcc tgctcatctt
     4321 tttaagcggt catcgccact ttcagcagac gcgcggtgtt aatcgccccg cgctgcgggc
     4381 ggttaaattc gcccttccaa cctggggttg gctggtatta atgctgtgta tcgcgccggt
     4441 attcttcacc ctcctgctgg aaaataactg gtctggctat gtgctggcca ttgtctgcgt
     4501 cttcgcggcg caacttatcg cccgtattat ggttaaattt cccgaacacc gtcgcgcctt
     4561 gtggcaaatc gttctgttaa tgatcaccgg cactctcttt tgggttctgg cgcagcaggg
     4621 cggaagttcg atcagtttat tcatcgaccg ttttgtcaac cgccactggc tgaatatgac
     4681 cgtccccacc gcattgttcc agtcggtcaa tgcgattgcg gtgatggcgg cgggcgtggt
     4741 gctggcgtgg ctgagcagcc cgaaagagag cgcccgctcg gtgctgcgcg tctggcttaa
     4801 atttgccgtg gggctgatat taatgggcgg cggttttatg ctgctggcgc taaacgcgca
     4861 tcaggcccgg ttagatgggc aggcatcaat gggaatgatg atcgcagggc tggcgctgat
     4921 gggctttgcg gagctgttta ttgatccggt cgcgatggcg caaattaccc gcctcaatct
     4981 gcctggcgtc acgggcgtac tgaccggtat ttatatgctg gcgaccggcg cgatcgctaa
     5041 ctggctggct ggcgtcgtcg cgcaacaaac cacggaatcg caaattagtg atacggcggt
     5101 agccgcctac ggacactttt tctcgcaaat gagcgagtgg acactaagtt gcgtggcgct
     5161 gatcgtcgcc attgtcggcc tgagatggat ttgcacccgg actacatcgg cgctaccgca
     5221 gggcgattaa acggtggttc gctgcccaca aggaggagac gggcagcgaa tcggcacatc
     5281 agatagccgc gtcgtcttct tcgccagtac ggatacgaat aacgcgggcg acatcaaaga
     5341 caaagatctt accgtcgccg attttccccg tctgcgcggt acgaatgatg gtatcaacac
     5401 aggtatccac gatgtcgtca ggcacaacga tttcaatttt taccttcggc agaaaatcca
     5461 ccatatattc cgcgccgcga tacagctcgg tgtggccttt ttgacggcca aagcctttga
     5521 cttcagtgac cgtcataccg gtaataccta cctcggccag cgcttcacgg acatcgtcca
     5581 gcttgaaggg tttaataatc gcatcaatct ttttcatgct attccttgaa aaggtcgcct
     5641 gtgttttgat cggttaaacg taacatattt cgcgctactt tacggcatga aaactactct
     5701 ttgaaatcat tcgcatccag ttcgtgacgg gagagtagct tatagaattc cgtgcggttg
     5761 cgccccgcca tccttgccgc gtgcgtcacg ttacctttgg taatttgcag taacttgcgc
     5821 agatagttca gttcaaattg gtttcgcgct tcggcaaaag ttggcagcgc ggtgttttcg
     5881 ccttccagcg cctgctcgac caatgcatcg ctgatcaccg gcgaagaggt taacgccaca
     5941 cattgttcaa tgacgttgac cagttggcgc acgttgcccg gccagcttgc cgtcatcagc
     6001 cgtttcattg catcagtaga aaaggcgcga acaaacggtt tatgccgctg tgccgactgt
     6061 ctgagcagat gattagccag cagcggaata tcctcggtac gctccgccag cgccggaatt
     6121 ttcaggctca cgacattcag ccggtagtac aaatcttcac gaaattcgcc ccgcgccatc
     6181 gccttcggca gatcgcggtg cgtcgcggaa ataattcgca cgtcgatatc aatatcgcga
     6241 ttgctgccca gcggcctgac tttgcgctcc tgtaacaccc gcagcagctt cacctgtaac
     6301 ggcgcgggca tatcgccaat ttcatccaga aacagcgtgc cgccttccgc cgcctggaac
     6361 aacccttcac gattgctcac tgcgccggta aaggcgccgc gcgcatggcc gaataattcg
     6421 gactccagca actgttccgg taacgcgccg cagttgatgg cgacaaacgg cttgttattg
     6481 cgcgggctgg cattatgaat cgcctgtgcg aaaatctctt tcccggtgcc gctttgtccg
     6541 ttaatcaata cgctgacatc cgactgcgcg accatgcgcg cctgttcaag cagtcgcagc
     6601 atcagcgggc tacgggtaac gatagcgttg cgccagctat cgtccgtcgc gggagcggac
     6661 tgctccagcg cttcatctat cgctttatat aacgcgtctc tgtcgatcgg cttcgtcaaa
     6721 aagctgaata cgcccttctg ggtagcggcc accgcatccg gaatagaacc atgcgccgtc
     6781 agaataataa ccggcattcc cggctgtact ttctgaattt ctgtgaacag ttgcatacca
     6841 tccatttcgt ccatgcgcag gtcgcttatt accagatcca ctttttcccg atgcagtacc
     6901 cgtagtcctt cctggccgct ctctgcggtc acgacgctgt atccttcact ggtcaggcgc
     6961 ataccgagca atttcagtaa tccgggatcg tcatcgacca gcagcaggtg cgccggttta
     7021 cggcttatca tggcgttacc tcatcttgtg acggcgacgg cgccgcgcca tcttcagacg
     7081 tcgcgggttt gtcattcgta tgcggcgtat cggcgttgta attccctgcc ggttttcgtg
     7141 tcgaaagctg gcgctcaatg tcggttaaac tctccagctt acgggtagta agatcgagct
     7201 gcgtttgcaa ggcctgttgc tgctggcgca acgcatccag ctcactatct gacgtttgct
     7261 ggagtttgct ataacgctga cgttcggcag aaagcgctaa ttgcagcgcc tgaccgtcat
     7321 gccagatttg gtagacgggc cgtacctgag ccggtatttg cgcgcttaac gcctccagac
     7381 gggtcactat ggcgcgccgc tccggcggcg taatttttgc atccgccagt aaaatcccgc
     7441 gcctgaaggc attctgccag ttatcatccg tcaacgagcg cgcctctgcg cgcgactgaa
     7501 ccggcatcag acgatcggcg cagtcaatcg tgcgtagcca gtacagcgga ttcgtctcca
     7561 ccgcctgccc gcgtagcgac cagatatccg cgcacgccgt cgggagataa tccgccagtt
     7621 gataatgggg gagcgtgtcc tgcgctgcgc taccgggcag ttgctgtgaa gcatggggaa
     7681 cacatgcggt cagcgccaga cacgatatgc ccaccggtat tccccatcgc aaaaggcatc
     7741 gtttaatagt ttggacgaaa acgtgtgaca tacgcaccag gcttaaattc atattagtgt
     7801 ttgtcagatg caggcaatgg cagcgagatg cgaaaacaaa cttcctgcgc tttgtcatcc
     7861 accagctgga tctctccctg cattcgacga atacaatctc tggcgatact cagccctaac
     7921 ccactgcctt ttaccgcccc ttttcgctgg tggcttccct ggaaaaaagg ctcaaaaatc
     7981 atttctcttt cggtttgcgg aatcggttcg ccgctattaa ccacatcgat ataaaccgtg
     8041 gagccctgag agcgactacg gatacaaatg ttaccggatt cagcgccata gtgcacagcg
     8101 ttggaataga gattatccag cacgctcatc agcaacatgg gctctgctat gcagcgttcg
     8161 gcctccaggt cgacatcggt atgcatcatt ttagcgcggg caggcaaact gtgggcggaa
     8221 accaccatat ccacaagcgg cgcgatatcg accgcttcca gctctgtggc actgtctacc
     8281 agtttccggt tgtaatcaag caattgctca atcaattttt gtaaattacg actgctgtca
     8341 tccagaatat cgaccacctc tttttgctcc ggcgtcagcg gcccaaccac ctgatcggcc
     8401 agcagctctg tcccctcgcg catactggcc agcggagttt tcagctcatg ggacaagtga
     8461 cgtagaaact gatggcgttg ggattccagc cacgccagac gctcactcag ccagataatg
     8521 cgctgcccca ccgatcgtaa ttcacgcgga ccggtaaagg tgacggtatt ccccaaagaa
     8581 cggccttcgc ccaggcgatt aatcatccgt tcaattcctt tcaccggccc gataatcatg
     8641 cgggtaaaaa gtagcaccat cgccaggctc accagaaata gcaccagcgc ctgccagccg
     8701 aaaaattgtc cgcgctcggc gatttcttgt tgtaactgct gcccgcgcga gtaaaccaca
     8761 gtacgcgtcg cctgcaccat ttccgtattc gcgttggcaa aggcctccag acgcgcggcc
     8821 gctgccgctt ccgggccgct atctttacac tgcaattgcg ccagcgcgtt taaatcctgg
     8881 cgtaacgcct gatacaactt atcatccggc aagacgccgg catgggcatc cagcatatcg
     8941 ctatagcgct tacgctggct ttgatacact tttgtcagcg tcggatcgtc aagcacgcaa
     9001 tactgtcggt agcttcgctc catctccagc gcgacgttgg tcatcgcctc gctgcgccgg
     9061 gcgtcaataa gcgtgctgcg gttagtcacc gcagcctgat cgcttaacgc gttaaggctt
     9121 tgccacgcct gccaggccag aaccagcaac ggcagcagga tcagcaaaaa ggccagcatg
     9181 accaattgtc gtaaagaacg ggggaaaaca gaccagcgct tcaacgtgtc gctcacataa
     9241 aaagaagaat aaaaaagatg ctaaccgagg ggagcgtcag atacaacaaa gccgggctaa
     9301 acccggcttt gttatggaat aaggcggtgc ctaactcgac gtttcgcccg gaggttgata
     9361 aagctacgct attatcagaa gttagacggc aggcaccttg ttgtgcgtca ttcgaagttt
     9421 atgtagcgcg tccctaaggg gctgacataa gaaggtgaat gagccactgg ttaccattat
     9481 gcagtaattg tgccaacatt caaaagactt tgttaacaca atgatagata tgaaaaatat
     9541 cgttattcat gctaaaaatg gctctgtctg ttttttgtcc cttctgtcgt caatcagcaa
     9601 cacctgcaac acctaaaaat aaaatcattt aaaatcaaat agttaaatgt ctctttttgg
     9661 cgacaaccta tccccactca tgtcgggatt tcccgacact ttaatcttgc ggcataagcg
     9721 ctagtttatt gccggatggc ggcgtaaacg ccttatccgc cctaccgctt gacgttcaag
     9781 acggtagcta caaccgcgct tccccgtggg cctgataagc gccgtctaca aaaaagcccc
     9841 tcgtgaagag gggcttaatg gctatcgggc taattaacca agctgcttac gcgcattacg
     9901 gaagatacgc atccacgggc tatcctcgcc ccagttttcc gggtgccagg agttggcgac
     9961 ggtgcggaat acgcgttccg gatgcggcat cataatcgtc acccgaccgt tttcggtcgt
    10021 caccgccgtg atgccgttcg gcgaaccgtt cgggttagcc ggataggttt cggtcacctt
    10081 accaaagtta tcaacgtagc gcagagcgac caggcctttg ctctcaagcg cggcaagatg
    10141 cgcatcgtca cgcacctcaa cgcgcccttc cccatgggaa accgcaatcg gcatctgtga
    10201 gcctaccatt ccttgcagca gcagcgatgg gctttgcgtc acttccacca ggctgaagcg
    10261 ggcttcgaag cggtcagaat ggttacgtac aaaacgcggc cacagttcgc tgcccgggat
    10321 cagctcgcgc agattcgaca tcatctggca accgttgcac acgcccagcg ccagcgtctg
    10381 cggacgatgg aagaaggttt cgaattcgtc gcgcacccga tggttaaaca gaatggattt
    10441 cgcccagcct tcgcccgccc ccagcacgtc gccgtaggaa aagccgccgc aagccaccag
    10501 cgcatggaag ttgcccagac cgatacgacc gcccagcagg tcgctcatat ggacgtcaat
    10561 cgcgtcaaag cccgcacgat ggaacgccgc cgccatctcc acgtgagagt tcaccccctg
    10621 ctcgcgcagt acagcgactt tcggtcgtgc gcctgtcgca atgtacggcg cggcgatatc
    10681 ttcattaata tcaaacgaca gcttcacgtt gaggcccgga tcggcatcat tcgctttcgc
    10741 ctcgtgttcc tggtcagcac attgcggatt gtcgcgcaga cgctgcatct gccaggtggt
    10801 ttccgcccac cagacacgca gcgtagtacg gctttcgctg aataccgtcc gatcattagc
    10861 ggtaatcaca aagcgatcgc cagccagggc ctgaccaagg tagtggacgc agtcagcaag
    10921 accgtactgc gccaacagcg tttcgaccgc gtctctgtct tcagcgcgta cctgaatcac
    10981 gccgcccagc tcctcgttga acagtgcggc cagatggtca tcgcccagcg cggcgatatc
    11041 gacctgcacg ccgcagtggc cggcaaaggc catctcggcc agcgtcacca gcagaccgcc
    11101 gtcggaacgg tcgtgccatg ccagtaattt acgcgcagca accagcacct gcatggcgtc
    11161 atagaagcct ttcagttgcg caacgtcacg cacgtccgcg ggtttgtcgc caagctgacg
    11221 atagacctgc gccaacgccg ttgcgcccag cgcgttgtgg cccttgccaa gatcgatcag
    11281 cagcaaggcg ttatcttccg ttgacagctg cggcgtaagg gtgtgacgca cgtcttccac
    11341 gcgggcaaac gcggaaatca ccagcgacag cggcgaggtc atttcgcgct gttcgttgcc
    11401 ttcctgccag cgggttttca tcgacatcga atctttaccc accggaatcg tcaggccaag
    11461 ctgcggacag agttcctctc ccaccgcttt aaccgcgtca tacaaaccgg catcttcgcc
    11521 aggatgaccg gctgccgcca tccagttagc ggaaagctta atgcgcttga tatcgccaat
    11581 ctgcgtcgcg gcaatgttag tcaacgcttc accgacggcc agacgggcgg aggcggcaaa
    11641 gtccagcagc gccaccggcg cgcgctcgcc aatcgacatc gcttcgccgt agtagctgtc
    11701 gaggctagcg gtagtgaccg cgcagtcagc taccgggacc tgccacgggc caaccatctg
    11761 gtcacgcgcc accataccgg tgacggtacg gtcgccaata gtgacaagga aggttttttc
    11821 cgccacggtc ggcagatgca gaacacgatt taccgcgtcg gcaatcgtga tatccgcgcg
    11881 gttcagcgca tcgcctttcg ccttcaatgt ttgcacatcg cgggtcattt tcggtgtttt
    11941 gcccagcagg acatccagcg gtagatcgat cggctgattg tcgaaatggt tatcatgcaa
    12001 cgagagatgc tgttcttcgg tagcgtcgcc aatgaccgca tacggcgcgc gttcgcgctt
    12061 acacagttca tcgaacagcg gtaactggtc agccgcgacc gccagcacat agcgctcctg
    12121 ggattcgtta caccagattt ccagcgggct catgcccggc tcgtcgctaa gaatgtcgcg
    12181 cagttcgaat ttcccgccgc gcccgccgtc gcttaccagc tccggcatgg cgttggagag
    12241 accgcccgcg cccacatcat ggataaacag gattgggtta gcgtcgccca actgccagca
    12301 gcggtcgatc acttcctggc agcggcgttc catttccggg ttgtcgcgct gaacagaggc
    12361 aaaatcgaga tccgcatcag actggccgga agccattgac gatgccgcgc cgccgccgag
    12421 gccgatattc atcgccgggc cgccaaggac gatcagcttc gcgcctacga cgatctcgcc
    12481 tttctgcacg tgatcggcgc ggatattacc gatcccgccc gccagcatga tcggcttgtg
    12541 atagccacgc agctcttcgc cattgtggct gttcactttc tcttcataag tacggaagta
    12601 accggtcagc gccgggcgac caaattcgtt gttaaacgcc gcgccgccca gcggaccttc
    12661 ggtcatgata tccagcgcgg tgacaatacg ttccggcttg ccaaaatcct cttcccacgg
    12721 ctgttcaaag cccggaatac gcaggttgga aacggagaag cctaccagcc cggcttttgg
    12781 tttcgcgcca cgcccggtgg cgccttcatc acgaatttcg ccgccggaac cggtcgccgc
    12841 ccccggccac ggagagatgg cggttgggtg gttatgcgtt tcgaccttca tcagaatgtg
    12901 cgcgggctcc tgatgaaaat cgtaacggcc ggtattgtgg tcggcgaagt agcgccccac
    12961 cgcagatcct tccatcaccg cggcattgtc tttataggca gagagcacat agtccggcgt
    13021 ggtttcgaag gtgtttttaa tcattttaaa cagcgacttc ggctgcggtt taccgtcgat
    13081 aatccagtcg gcgttaaaaa tcttgtggcg gcagtgctcg gagttcgcct gggcgaacat
    13141 gtacagttcg atatcgttcg ggttgcgtcc cagtttggta aacgcctcct gcaaatagtc
    13201 gatttcatct tccgccagcg ccagaccgag acgcaggtta gcgtcaatta acgcctgacg
    13261 gccttctccc agcagatcga cactggaaac cggcgcaggc tgatggtgga taaacagttt
    13321 ttccgcatcg gttaaagaag agaacaccgt ctccatcata cggtcgtgca gctctgcggc
    13381 cacttgtcgc cactgttccg ccgtcaacgt cgaagcctcg atatagtacg ctacgccgcg
    13441 ctccagacgg tcaatctgtt gcaggccgca gttgtgggcg atatccgttg cttttgaaga
    13501 ccagggggag atggtaccag gacgcggtgt gaccaacagg agtttacccg ccagcgtatg
    13561 gctgctaagc gccgggccgt attgcagcag acgggtaagc tgcgcctgct cgctatcatt
    13621 taacggggcg ttcaggtcag caaaatggac atactcagcg tatatattgt ggacctggag
    13681 gttggcagcc tgaaagcgcg ccagcagttt attgatacgg aatgcagaca gtgcaggcga
    13741 accacgcaga atttccatca taagtctctc gtcttctaag cttcggtgtg cgcaaggggg
    13801 gaaacggccg ccattataaa gaatctgacg cgccgacgaa accgtttgcg tagaaataaa
    13861 atcaccgctt tttcttgtca tacggtgcgg ctatcgttgc gaataagttg ccaactggcg
    13921 cattgttacg caaaatgccg ctcattagtg acttatctat tgcagcaaaa catctttttc
    13981 agcccgaggc aacgcacgat ccagagaatt aactaattga aaaaattaaa gattaattat
    14041 ctgttcatcg gcatattgac gctgctgctg gcagcagccc tttggccctc aatcccctgg
    14101 ttcggtaaaa ccgaaaacca tatcgccgcg attcaagccc ggggggtact gcgcgtcagt
    14161 acgatcgact cgccattaac ctattccgtt atcaacggta aaaaatatgg tctggactat
    14221 gaactggcgc agcagttcgc caactatctc ggcgtgaagc tgaaagtgac ggtgcgccag
    14281 aatatcagcc agttgtttga cgatctggat aacggcaatg ccgacctgct cgcggcaggg
    14341 ctggtctacg acagcgcgcg cgttaaaaac tatcagcccg gccccatgta ttattcggtt
    14401 tcgcaacagc tcgtttaccg ggtcggacaa tatcgcccac gttcgctggc gaccgttaac
    14461 gagaatcagc ttaccattgc gccagggcac gtcgtggtca atgatttaca gcgtttaaaa
    14521 gagacaaagt ttcccgacct gagctggaag gtggatgata aaaaaggctc gacgacgctg
    14581 ctggaagagg tcatcagcgg caaactggat tacaccattg ccgattcagt ggcgatcagt
    14641 ctgtttcagc gcgtccatcc cgaactggcc gtggcgctgg atgtcacgga tgaacagccc
    14701 gtgacctggt ttagccgact ggacgacgat aatacgctct ccgccgcgct gctcgatttt
    14761 ttcaattcga tcaatgaaga cgggtcgttg gcgcggatcg aagagaaata tctggggcat
    14821 ggcgatgatt tcgactacgt tgatacccgc tctttcctgc gagcggtgga taacgtcctg
    14881 ccggagctgg aaccgttatt taaaaaatat gccaaagaga tagactggcg cctgctggcg
    14941 gcgatttctt atcaggaatc acactgggac ccgctggcga cctcgccaac cggcgtgcgc
    15001 ggcctgatga tgctgactaa aaataccgcc caaagtctgg ggctgaccga ccgtaccgat
    15061 gcggagcaaa gcatcagcgg cggtgctcgc tatcttgaag atatgatggc taaagttccc
    15121 gaaaccgttc cggaagacga gcgtatctgg tttgccttag ccgcctacaa tatgggttat
    15181 gcgcacatgc tcgatgccag atcgctgacg gtaaaaacca aaggcaatcc ggatagctgg
    15241 accgatgtga agcagcgttt gcctctgtta agccaaaaac cgtattacag taagctaacc
    15301 tacggttacg cgcgtggaca tgaggcttat gcttatgtgg aaaatatccg taaataccag
    15361 ataagtttgg tggggtattt gcaggaaaaa gaaaagcagg aagcggaagc tatgaaactg
    15421 gcgcaggatt acccggcggt gtagccggag gagctgaata aagccccctt ccccttcctg
    15481 tcgtttttat cgcagtcatc aggctacctg acgcattcgc cgtctttact gtttacgccg
    15541 cagaagaaag aagaaaaata gcgcgatggt cttatcggat ggcgacgcgc aacgtcttat
    15601 ccggcattgc gctatactgc cggccccgcg ccttccgcac ggtcggcttt cttcagagct
    15661 ttaatttcct gacgacgcat acggaaaaaa tcactgagca gcgtcgcaca ttcatcgcgc
    15721 aacacccctt caataatctc gacccggtga ttcattcccg gatggtgcag cacgtcaatt
    15781 agcgatccgg ccgcgccagt ttttgcatcg cgcgcgccaa agacaacgcg tccaatgcgg
    15841 ctatgcacca tagcgcctgc gcacatcaca cagggttcca gcgtgacata cagcgtggta
    15901 tccagtaacc gataattctg caataccaga ccgccctgac gcagcgccat tatttcagca
    15961 tgcgcagtag gatcgtggcg gccaatgggt cgattccagc cttcgccaat gacgcgatgg
    16021 ttatgcacca ataccgcgcc aaccggaacc tcgcgttcgt cccaggcgcg tttcgccagc
    16081 gtcagcgcgt ggcgcatcca gtattcgtga tctaattcga catcagacaa agaggtaact
    16141 ccggtaatga aagcgggcgg cattatacac agacgctatg cgtttcacta ttcgagctgc
    16201 tgcaactcgc cgtgcggcgt cacccgccag cgatgctggc aaaaataaag cagcgggtta
    16261 tcctgtttgc tgtcgctgta gccgctataa agacgcaacg gcgtaccgat tttacgttcc
    16321 agttgcgcga ctttttcatg gcccagacag cgcacggtta atacccagcc gccataccgt
    16381 cgcgccatct ggctggcgat gaggttaaca cgcggcaacc acggcgtatc aaaatagact
    16441 tgctctacca atgattgcgg agaaccggta ataagccaga tatccgcgtc agagctcaat
    16501 agataggtgg tcagacgctc ctgtacgacc ggaaacgccg tgacgttagc gcgaaaccaa
    16561 cggacaaaat ccgcctgatg cgcctgcaaa cgcgtttcgc tatggccaaa agtacagccc
    16621 cacaataaca gactcatcgg ccagcgggcc gcacgccctt ttaccagtaa accgataccg
    16681 ataatgggca acaacggcag tacgagcagc gcatttagcg gctgacggcg cagcaaataa
    16741 cgcagaaaac tgccgaacat atcctgttga tataacgttc catccaaatc aaaaaagacg
    16801 acacgacgct cgtggctgac caaaccttac tcctctggat cattgaaccc cagcagccag
    16861 gtaaaaataa acccggcaat taccgctatt aaatagccta acagatagaa caggactttt
    16921 ccggcaacaa ttgttaatgc cagcggcaaa ccggaaatac caaaggtaat taccgtcgcc
    16981 actttccagt agctgatcaa cgccccgcct accgcgccgc cgaggcaagc gccaataaat
    17041 ggcttaccca atggcagcgt gacgccaaaa atcagcggct cgccaatccc cagcagtccg
    17101 accggaagcg cgcctttaat cacctttttg agccgcgcat tgcgggtttt catcagtacg
    17161 gcaatggccg cgcctatctg accaaccccc gccatcgcca ggatgggaaa cagcgcgtta
    17221 tagccgtgcg cttgcaccag ctccacatga ataggcacca gcccctgatg cagcccgatc
    17281 agtaccaacg gcaggaaggt tccggctaac accgcgccca ccagaaaacc gccgcgatcg
    17341 atagcccagg acgcgccgtg agcgatagcg tctgaaatcc agccgccaag cggttgcaga
    17401 gcgacaatcg ctaccgcgcc ggtgataaca gtcgtcaata aagggttaag aattaactcc
    17461 agcgaccccg gcagcagctt acggaactgg cgctcaatcc agcacattaa cgccaccacc
    17521 agcaggacgg cgataacgcc gccccgtccc ggctgaagcg cctcgccaaa gagcgtaatc
    17581 tgcgccagtt gcgggctgga aaggatcccc gccatcacgc cgcctaacgc ctgcgatccg
    17641 ccaaagactt tcgcggtatt gacgccaacc agaatgttca tgatagcgaa caccgcgcta
    17701 ccaaatatcc ccatcaggcc cagcaggtta ggatagtgga cggcaacatc gccgacgata
    17761 tccgggcgtt taagaatatt gataatgccg gtaatcaagc cggatgcgat aaaggcggga
    17821 ataagcggaa taaaaacatt cgccagctta cgcaacgcat cgctcatcgg cgctttatac
    17881 ttcgctttcg cctcggattt ggtacgcgcc atagcatcgt ccggctttac accacctgcg
    17941 gcaatctgca cgcgcatcgc atcaaccacc tgtgcagcct tccccggccc aacgatcagc
    18001 tgatgttgct ccccttgctt tacgtatcca ctgacgccag gcaacgcttt taagcgcgga
    18061 atatccagtt ggctgtcgtc ctgtacctcc actctgactc gcgtcataca gttttccagg
    18121 cgcagaatat tttgctctcc gccgatacca cgtaaaatgt cgctggcgag cgctgccgtc
    18181 ttatccatac acacctcttt agtgttctaa cgccgccctt aaaaagccct gatgagcggc
    18241 gagtttttcc ctggcggctg cagcatccag ccccgtaagc gccatcaaaa tggcgggctt
    18301 aacctcaaaa tcggtctgtt tcagcaacgt ttccgcctct tcacgaccta tcccggtcgc
    18361 ttcaacgacc atccgacacg cgcgatcgac cagtttgacg ttggtggctt tcatatccac
    18421 catcaggttc tgatagacct taccgaactt caccatcgcg ccggtagaaa tcatattgag
    18481 caccattttc tgcgcggtgc cggatttcag ccgcgtggag ccggtaagcg cttccggccc
    18541 gacaacgggc gaaatagcga tattagcctc ccgcgcaata ggcgaatctg gattacagga
    18601 gacggcaaca gtggtacaac cggactgtcg cgcatagcgc aggccaccaa tcacataggg
    18661 tgtacgaccc gacgccgcga gccccacgac cagatcctgt tcttgcagat ttagcgcgac
    18721 aagatcgtct tcgcctgcct gttggctgtc ttccgcgcct tcgaccgcct tcagcaacgc
    18781 gcccggcccg ccggcaatca gcccgacgac cagaccgtgc ggaacgccaa acgtcggggg
    18841 gcattctgag gcatccagta cgccaagccg accactggtg cccgccccca tatagatgat
    18901 acgtccgcca gacttcagcg ccgccgcagc agcatccacc gcacgcgcaa cgtcaggcag
    18961 agtggctttt actgcttccg ctaccagcgt atcctgttca ttaaaacgct taactaattc
    19021 aggagtagac aacgcatcca gatccatcgt ttgcgggtta cgggtttcag acactaaggc
    19081 accaagattc atttttgtcc ctctggaatt tttaattcat aataagcgtc catgatggaa
    19141 tagaatattc ccccaggcga gtgaaatttc gttttgtcgt cgccatcacg tttcgcagga
    19201 gctgcccatg aactgtttga ttcgtattcg ccagcgttat ccggatctcg cgcaaagcga
    19261 caggaaactg gcggattatc tgctcgcgca accggatacg gcgcgacatc tgagctcgca
    19321 gcaactggcg gccgaagcgg gcgtcagcca atccagcgta gtcaagttcg cgcaaaaact
    19381 ggggtttaaa gggtttccgg cgttgaaact ggctatcagc gaagcgttgg ccagcaatcc
    19441 taatccgcat tccgttcccg ttcataacca gattcgcggc gacgatccga tgcgcctggt
    19501 cggggaaaaa ttaattaaag agaatgtggc ggcgatgcac gccacgctgg acgttaacag
    19561 tgaagaaaag ctgttagaaa gcgtcacgat gctgcgccac gcccgccgta ttgtgatcac
    19621 cggaattggc gcctctgggc tggtggcgca aaattttgcc tggaagctac tgaagattgg
    19681 cattaacgcg gtggttgagc gcgatatgca cgccctgctg gcgacggtgc aggcgctggc
    19741 gccggaggat ctgctgctgg cgatctctta ttccggggag cggcgcgagc tgaacctggc
    19801 ggcggacgaa acattacgcg caggcgcgaa aatcctggcc attaccggtt tttctcccaa
    19861 cgccttgcag cagcgcgcca cccgctgtct gtatacgatt gccgaagagc aggcgacgcg
    19921 tagcgccgct atctcctcga cacatgcgca aatgatgttg accgacttac tgtttatggc
    19981 gctggtacaa caggatttag agcgggcgcc ggagcgtatt cgccatagcg aggcgctggt
    20041 aaaaaaactg gtttgaaaat ggctcttccg cctcatgcag aagagctatc aagtttattg
    20101 cgcttcttta gcgtgaatca attgcgtcag gagtgtgtta accggtacgg caatattgtt
    20161 ctgagcgccg attcgcgcaa tcgcaccatt taaatagtcg atttcggtca gtcggccttt
    20221 atgtaaatcc tgatgcatag aaggatagtg gtggccgctc tcacgcggat cgaacacttt
    20281 cttcaccgta ttcatcacca tttgctcagt caacggaata ttctggctgg cagcaactaa
    20341 cacaaactca tcaactaccg cttgcgctaa atctaaagca ccaggccgct gaccaaatcc
    20401 gccgacatta caatccagta acgcgcaata ggtgttcatt acgctattaa aggctgcttt
    20461 cttccagatc gataataata cgtcagggct tatttcagca ttcaatccag cactattaag
    20521 ggtggcaatg accttagcct cttgagccga atcttggctg gctatcggct gcagttcaat
    20581 cgttccggta ccggtggcca taatatgccc agccccctcc agttcgctgg accataacgt
    20641 cacacccgca tagattttct gccgatcgac atatttctcc agggtttcga tatttcccag
    20701 gccgttagat aaaatcatca cgaccttcgc ggctggcagc agcggcttaa tacgctgtaa
    20761 catgctatcc aactgcatgg ctttggtaaa cagaataacc agctcaaact ccccctgg
//
LOCUS       DAJVBX010000066        20677 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.066, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000066 DAJVBX010000000
VERSION     DAJVBX010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 20677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20677
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.066"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            1..1326
                     /gene="gdhA"
                     /locus_tag="OPV72_002078"
     CDS             1..1326
                     /gene="gdhA"
                     /locus_tag="OPV72_002078"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002440315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HCR9914377.1"
                     /translation="MESFLNHVQKRDPHQTEFAQAVREVMTTLWPFLEQNPRYRHMSL
                     LERLVEPERVIQFRVVWLDDKNQVQVNRAWRVQFNSAIGPYKGGMRFHPSVNLSILKF
                     LGFEQTFKNALTTLPMGGGKGGSDFDPKGKSEGEVMRFCQALMTELYRHLGPDTDVPA
                     GDIGVGGREVGFMAGMMRKLSNNSACVFTGKGLSFGGSLIRPEATGYGLVYFTEAMLK
                     RHGLGFEGMRVAVSGSGNVAQYAIEKAMAFGARVVTASDSSGTVVDESGFTPEKLARL
                     CEIKASRDGRVADYAREFGLTYLEGQQPWSVPVDIALPCATQNELDVDAARVLIANGV
                     KAVAEGANMPTTIEATDLFLEAGVLFAPGKAANAGGVATSGLEMAQNAARLSWKAEKV
                     DARLHHIMLDIHHACVKYGGDNKHTNYVQGANIAGFVKVADAMLAQGVI"
     gene            complement(1356..3305)
                     /gene="topB"
                     /locus_tag="OPV72_002079"
     CDS             complement(1356..3305)
                     /gene="topB"
                     /locus_tag="OPV72_002079"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HCR9914378.1"
                     /translation="MRLFIAEKPSLGRAIADVLPKPHRKGDGFIECGNGQVVTWCIGH
                     LLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPSVTKQLNVIKRFLHQAGEIIHAG
                     DPDREGQLLVDEVLDYLQLPAEKRQQVRRCLINDLNPQAVERAIDRLRANSDFVPLCV
                     SALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVA
                     KDFFEVKAHIVTPADERFTAIWQPSEACEPYQDEEGRLLHRPLAEHVVNRINGQPALV
                     TSYNDKRESESAPLPFSLSTLQIEAAKRFGLSAQNVLDICQKLYETHKLITYPRSDCR
                     YLPEEHFAGRQAVMNAISVHAPDLLPQPVVNPDTRNRCWDDKKVDAHHAIIPTARSSS
                     VHLTENEAKVYTLIARQYLMQFCPDAVFRKCVIELEIAKGKFVAKARFLAEAGWRTLL
                     GSKERDEENDGTPLSVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQ
                     DKDLKKILRATDGLGTEATRAGIIELLFKRSFLTKKGRYIHSTDAGKALIHSLPEMAA
                     RPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIDQAKRTPVKRFRGIVAPGGGE
                     KKKSAPRKRAGKKSPPAEETGRQTE"
     gene            complement(3310..4353)
                     /gene="selD"
                     /locus_tag="OPV72_002080"
     CDS             complement(3310..4353)
                     /gene="selD"
                     /locus_tag="OPV72_002080"
                     /EC_number="2.7.9.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenide, water dikinase SelD"
                     /protein_id="HCR9914379.1"
                     /translation="MSKQAIRLTQYSHGAGCGCKISPKVLETILHSEQAKFVDPNLLV
                     GNETRDDAAVYDLGNGTSIISTTDFFMPIVDNPFDFGRIAATNAISDIFAMGGKPIMA
                     IAILGWPINTLSPDIAREVTEGGRFACRQAGIALAGGHSIDAPEPIFGLAVTGVVPTE
                     RVKKNSTAQAGCKLFLTKPLGIGVLTTAEKKSLLKPEHQGLATEVMCRMNVAGAAFAN
                     IDGVKAMTDVTGFGLLGHLSEMCQGAGVQAMLCYQDIPKLPGVEEYIALGAVPGGTER
                     NFASYGHLMGDMSREVRSLLCDPQTSGGLLLAVTPDAEDDVKATAAEFGIELTAIGEL
                     VEARGGRAMVEIR"
     gene            complement(4471..5022)
                     /locus_tag="OPV72_002081"
     CDS             complement(4471..5022)
                     /locus_tag="OPV72_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H nitroreductase"
                     /protein_id="HCR9914380.1"
                     /translation="MDALELLVNRRSASRLAEPAPVGEQLQNILRAGMRVPDHKSLQP
                     WRFFVIEGEGRDRFSAVLEQGAVAAGGDEKAIEKARNAPFRAPLIITVVAKCEENHKV
                     PVWEQEMSAGCAVMAMQMAAIAQGFNGIWRSGALTESAIVREAFECRPQDKIVGFLYL
                     GTPQLKASTTISTPDPTPFVRYF"
     gene            5196..7052
                     /gene="sppA"
                     /locus_tag="OPV72_002082"
     CDS             5196..7052
                     /gene="sppA"
                     /locus_tag="OPV72_002082"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HCR9914381.1"
                     /translation="MRTLWRFIAGFFKWTWRVLNFVREMVLNLFFIFLVLVGVGIWMQ
                     IGNGSNSEQTARGALLLDISGVIVDKPSTNHRLGALGRQLFGASSDRLQENSLFDIVN
                     AIRQAKDDRNITGIVLDLKNFTGADQPSMRYIGKALREFRDSGKPVFAVGENYSQGQY
                     YLASFANKIWLSPQGQVDLHGFATNGLYYKTLLDKLKVSTHVFRVGTYKSAVEPFIRD
                     DMSPAAREADSRWIGELWQNYLHTVSANRQISPQQLFPGAQAIIDGLTSVGGDTAKYA
                     LDHKLVDALASSADVEKALTKQFGWSKTENNYRAISYYDYSLKTPADTGGTIAVIFAN
                     GAIMDGEETPGNVGGDTTASQIRDARLDPKVKAIVLRVNSPGGSVNASEVIRAELAAA
                     RAAGKPVVVSMGGMAASGGYWISTPANYIVASPSTLTGSIGIFGVINTVENSLSSIGV
                     HSDGVSTSPLADISMTKALSPEVQQMMQLSIEYGYKRFITLVADARKRTPEQIDKIAQ
                     GHVWTGEDAKANGLVDSLGDFDDAVAKAAELAKLKQWHLDYYQDEPTVLDMVMDSMTG
                     SVRAMLPEAIQAMLPAPLVSAANTVKAEGDKLAAFNDPQNRYAFCLTCANVR"
     gene            7148..8164
                     /gene="ansA"
                     /locus_tag="OPV72_002083"
     CDS             7148..8164
                     /gene="ansA"
                     /locus_tag="OPV72_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HCR9914382.1"
                     /translation="MQKKSIYVAYTGGTIGMQRSDKGYIPVSGRLQRQLALMPEFHRP
                     EMPDFTIHEYAPLMDSSDMTPEDWQHIAADIKAHYDEYDGFVILHGTDTMAYTASALS
                     FMLENLGKPVIVTGSQIPLAELRSDGQINLLNALYVAANYPVNEVTLFFNNRLFRGNR
                     TTKAHADGFDAFASPNLPPLLEAGIHIRRLNTPPAPYGSGELIVHPITPQPIGVVTIY
                     PGISAEVVRNFLRQPVKALILRSYGVGNAPQNKAFLQELKEASSRGIVVVNLTQCMSG
                     RVNMGGYATGNALAHAGVIGGADMTVEATLTKLHYLLSQGLDTQAIRSAMAQNLRGEL
                     TPDD"
     gene            8191..8847
                     /gene="pncA"
                     /locus_tag="OPV72_002084"
     CDS             8191..8847
                     /gene="pncA"
                     /locus_tag="OPV72_002084"
                     /EC_number="3.5.1.-"
                     /EC_number="3.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional nicotinamidase/pyrazinamidase"
                     /protein_id="HCR9914383.1"
                     /translation="MTNRALLLVDLQNDFCAGGALAVAEGDSTIDIANALIDWCQPRQ
                     IPVLASQDWHPAQHGSFASQHQAEPYRQGKLDGLPQTLWPDHCVQHTDGAALHPLLNQ
                     HAIDACIYKGENPLIDSYSAFFDNEHRQKTTLDTWLREHDVTELIVMGLATDYCVKFT
                     VLDALELGYAVNVITDGCRGVNIHPQDSAHAFMEMAAAGATLYTLADWEETQGQAIAR
                     "
     gene            complement(9198..9476)
                     /locus_tag="OPV72_002085"
     CDS             complement(9198..9476)
                     /locus_tag="OPV72_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeaC family protein"
                     /protein_id="HCR9914384.1"
                     /translation="MNLDEIINSMTPEVYQRLSTAVELGKWPDGVALTPEQKENSLQL
                     VMLWQARHNTEAQHMTIDTHGQMVMKSKQQLKADFGITSKPIATLKMQ"
     gene            complement(9518..9931)
                     /gene="msrB"
                     /locus_tag="OPV72_002086"
     CDS             complement(9518..9931)
                     /gene="msrB"
                     /locus_tag="OPV72_002086"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HCR9914385.1"
                     /translation="MANQPSAEELKKKLSEMQFYVTQDRGTEPPFTGRLLHNKRDGVY
                     HCLVCDTPLFHSHTKYDSGCGWPSFYQPVSEEAIRYIDDFSHGMQRVEIRCGNCDAHL
                     GHVFPDGPQPTGERYCVNSASLAFSDEKNGDQLKG"
     gene            10273..11268
                     /gene="gapA"
                     /locus_tag="OPV72_002087"
     CDS             10273..11268
                     /gene="gapA"
                     /locus_tag="OPV72_002087"
                     /EC_number="1.2.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006322611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HCR9914386.1"
                     /translation="MTIKVGINGFGRIGRIVFRAAQKRSDIEIVAINDLLDAEYMAYM
                     LKYDSTHGRFDGTVEVKDGHLIVNGKKIRVTAERDPANLKWDEVGVDVVAEATGIFLT
                     DETARKHITAGAKKVVLTGPSKDNTPMFVKGANFDKYEGQDIVSNASCTTNCLAPLAK
                     VINDNFGIIEGLMTTVHATTATQKTVDGPSHKDWRGGRGASQNIIPSSTGAAKAVGKV
                     LPELNGKLTGMAFRVPTPNVSVVDLTVRLEKAATYEQIKAAVKAAAEGEMKGVLGYTE
                     DDVVSTDFNGEVCTSVFDAKAGIALNDNFVKLVSWYDNETGYSNKVLDLIAHISK"
     gene            11597..12481
                     /locus_tag="OPV72_002088"
                     /pseudo
     CDS             11597..12481
                     /locus_tag="OPV72_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460255.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="D-hexose-6-phosphate mutarotase"
     gene            complement(12580..13437)
                     /locus_tag="OPV72_002089"
     CDS             complement(12580..13437)
                     /locus_tag="OPV72_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HCR9914387.1"
                     /translation="MKSVKNVTFCGQVTLPAIGQGTWYMGERADQRQREVSALRAGLD
                     LGLRLIDTAEMYADGGAEKVVGEALAGRRDEAFLVSKVYPWNAGGQKIVAACEESLRR
                     LKTDYLDLYLLHWAGGFSFEETVEGMERLIAQGKIRRWGVSNLDYDDMQALWRIPGGQ
                     QCATNQVLYHLASRGIEYDLLPWCQQQRMPVMAYSPLAQAGRLRSGLLNHPVVNEIAQ
                     AHNATAAQILLTWVIAHPGVMAIPKAGSTEHVKQNAAALEITLSANELALLDNAWPAP
                     KGKTALDMV"
     gene            complement(13535..14731)
                     /locus_tag="OPV72_002090"
     CDS             complement(13535..14731)
                     /locus_tag="OPV72_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfatase maturase"
                     /protein_id="HCR9914388.1"
                     /translation="MSIVFNTVAKPSGSLCNLSCKYCFYLDKPRGQRVMSDDVLETYI
                     RRVIDDTPSSEVSFCWQGGEPTLCGLSFYQKVVCLQQRYANGKTIYNSLQTNGVLINE
                     EWAAFFVQHQFLIGISIDGPQVVHDNYRRTPSGRASFSRVVNAIRLLQANDVEFNTLT
                     VVNDASCRHGNAIYHFLTQELESKHLQFIPIVEPLAQKAQRSLTLSDNEDSPSLMPFS
                     VTPEGWGAFMCDVFDQWIRHDVGRIFVQLFDNLLGVWMGEPATLCTMQSTCGQSLLVE
                     QNGDVFSCDHFVFPAYKLGNLQQHSLEEMAASPFQQQFGAAKANLSSRCQNCTWRFAC
                     HGGCPKHRICMDGGERQNYLCKGYLEFFQHVTPYMNVMRQLLLNQRPAAHITRIVDMI
                     ADDVRQ"
     gene            complement(15021..15767)
                     /locus_tag="OPV72_002091"
     CDS             complement(15021..15767)
                     /locus_tag="OPV72_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MipA/OmpV family protein"
                     /protein_id="HCR9914389.1"
                     /translation="MTKLKLLALGVFIATSASVAHAESNLTLGAGVGVVEHPYKDYDS
                     DVYPIPVIAYESENFWFRGLGGGYYLWNDNADKLSIMAYWSPMYFKPGDSDDHQLRRL
                     DRRKSTMMAGVSYAHHTQYGFLRTSLAGDTLDNSNGIVWDLAWLYRYTNGGLTLTPGI
                     GVEWNSENQNDYYYGVSRKESSRSGLRGYNPNDSWNPYLELSANYNFAGNWSVYGTAR
                     YTRLSDEITDSPMVDKSWTGILSTGVTYRF"
     gene            16193..18127
                     /gene="yeaG"
                     /locus_tag="OPV72_002092"
     CDS             16193..18127
                     /gene="yeaG"
                     /locus_tag="OPV72_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase YeaG"
                     /protein_id="HCR9914390.1"
                     /translation="MNIFDHYRQRYEAAKDEEFTLQDFLTICRQDRSAYANAAERLLM
                     AIGEPNMVDTAQEPRLSRLFSNRVIARYPAFEEFYGMEDAIEQIVSYLKHAAQGLEEK
                     KQILYLLGPVGGGKSSLAERLKSLMQRVPIYVLSANGERSPVNDHPLCLFNPQEDAQI
                     LEKEYGIPRRYLGTIMSPWAAKHLHEFGGDITKFRVVKVWPSILEQIAIAKTEPGDEN
                     NQDISALVGKVDIRKLEHHAQNDPDAYGYSGALCRANQGIMEFVEMFKAPIKVLPPLL
                     TATQEGNYNGTEGISALPFNGIILAHSNESEWVTFRNNKNNEAFLDRVYIVKVPYCLR
                     ISEEIKIYEKLLNHSELAHAPCAPGTLETLSRFSTLSRLKEPENSSIYSKMRVYDGES
                     LKDTDPKAKSYQEYRDYAGVDEGMNGLSTRFAFKILSRVFNFDHAEVAANPVHLFYVL
                     EQQIEREQFPQEQAERYLEFLKGYLIPKYAEFIGKEIQTAYLESYSEYGQNIFDRYVT
                     YADFWIQDQEYRDPDTGQLFDRESLNAELEKIEKPAGISNPKDFRNEIVNFVLRARAN
                     NSGRNPNWTSYEKLRTVIEKKMFSNTEELLPVISFNAKTSTDEQKKHDDFVDRMMEKG
                     YTRKQVRLLCEWYLRVRKSS"
     gene            18250..19536
                     /locus_tag="OPV72_002093"
     CDS             18250..19536
                     /locus_tag="OPV72_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeaH/YhbH family protein"
                     /protein_id="HCR9914391.1"
                     /translation="MTWFIDRRLNGKNKSTVNRQRFLRRYKAQIKQSISEAINKRSVT
                     DVDSGESVSIPTDDISEPMFHQGRGGLRHRVHPGNDHFIQNDRIERPQSGGGGGSGSG
                     QGQASQDGEGQDEFVFQISKDEYLDLLFEDLALPNLKKNQHRQLNEYKTHRAGFTSNG
                     VPANISVVRSLQNSLARRTAMTAGKRRELHALETELETISHSEPAQLLEEERLRREIA
                     ELRAKIERVPFIDTFDLRYKNYEKRPEPSSQAVMFCLMDVSGSMDQATKDMAKRFYIL
                     LYLFLSRTYKNVEVVYIRHHTQAKEVDEHEFFYSQETGGTIVSSALKLMDEVVKERYD
                     PSQWNIYAAQASDGDNWADDSPLCHEILAKKLLPVVRYYSYIEITRRAHQTLWREYEH
                     LQATFDNFAMQHIRDQEDIYPVFRELFQKQSANQSA"
     gene            complement(19686..19892)
                     /locus_tag="OPV72_002094"
     CDS             complement(19686..19892)
                     /locus_tag="OPV72_002094"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914392.1"
                     /translation="MKRFKEIAAILLFALLAVGFTSSAMASSGSGGGPWDFDIYFPGH
                     YFFCKLQPPDSLQLPPPPGEYCWH"
     gene            20186..20359
                     /locus_tag="OPV72_002095"
     CDS             20186..20359
                     /locus_tag="OPV72_002095"
                     /inference="COORDINATES: protein motif:HMM:NF028464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914393.1"
                     /translation="MNLHHKALRHFISASVIVLTSSFLIYELIASDRAMNAYMRYIME
                     RADSSFLYDKYQN"
     gene            20378..>20677
                     /locus_tag="OPV72_002096"
     CDS             20378..>20677
                     /locus_tag="OPV72_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001258703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cylase"
                     /protein_id="HCR9914394.1"
                     /translation="MRTFEAPGDPVTAEKRRAFCDAFEAINGTHGVNLTRHNYPALHG
                     TLQTVATQCTDNLDDALLLPAFDQAVSINRAQDDHSHGLGTLELKFRYYVDLNKHY"
BASE COUNT         5012 a         5560 c         5263 g         4842 t
ORIGIN      
        1 ctggaatcgt tcctcaacca tgtacaaaag cgcgacccgc atcaaaccga gttcgcgcaa
       61 gccgtccgtg aagtcatgac caccctgtgg ccgtttcttg aacaaaaccc ccgttaccgc
      121 cacatgtctt tactggaacg tttggttgaa ccagagcgcg taatccagtt tcgcgtagtg
      181 tggctggacg ataaaaatca ggtgcaggta aatcgcgcct ggcgcgtgca gttcaactct
      241 gctatcggcc cctataaagg cggtatgcgc ttccatcctt cggtaaacct ttccatcctt
      301 aagttcctcg gctttgagca aacctttaaa aatgccctca ccacgttgcc gatgggcggc
      361 ggtaaaggcg gcagcgattt cgatccgaaa gggaaaagcg aaggcgaagt gatgcgtttc
      421 tgccaggcgc tgatgactga actgtatcgc catttagggc cggataccga cgtgcctgcc
      481 ggggatatcg gcgtgggcgg gcgcgaagtg ggctttatgg cgggaatgat gcgcaagctt
      541 tccaataaca gcgcctgcgt cttcaccggc aaagggcttt ccttcggcgg cagcctgatt
      601 cgtccggagg cgacgggcta tggcctggtc tacttcaccg aagcgatgct taaacgtcat
      661 ggtctcggtt ttgaagggat gcgcgtcgcc gtgtccggct ccggcaacgt agcgcaatac
      721 gccattgaga aagcgatggc ctttggcgcg cgcgtggtta ccgcgtcgga ttcgagcggg
      781 acggtggtcg atgaaagtgg cttcacgcca gagaagctgg cgcggctgtg tgaaattaaa
      841 gccagccgtg acggtcgcgt cgctgactac gcccgtgagt ttggcttaac ctatctggaa
      901 ggccagcagc cctggagcgt accggtggat atcgccctgc catgcgcgac gcagaacgaa
      961 ctggacgttg acgccgcgcg cgtactgatt gccaatggcg tgaaagccgt ggcggaaggg
     1021 gcaaatatgc caaccacgat tgaagcgacc gatctcttcc ttgaggcggg cgtactgttt
     1081 gcgccgggta aagccgccaa cgcgggcggc gtggcgacat cggggctgga aatggcgcag
     1141 aacgccgcgc ggttgagctg gaaagccgag aaagtggacg cccgtctgca tcatattatg
     1201 ctggatatcc accacgcctg tgtcaagtac ggcggcgaca ataagcatac taactacgtt
     1261 cagggcgcca acatcgccgg tttcgtgaaa gtcgccgacg ccatgctggc gcagggcgtc
     1321 atttaatccc gtcgccaggc cagatggctt tacgcttatt cggtctgacg gcctgtctcc
     1381 tcagcaggcg ggcttttttt gcccgctcgc ttacgcggcg cgctcttttt cttttctccg
     1441 ccgcctggcg cgactatccc tctgaaacgc ttcaccggcg tgcgcttagc ctgatcgatc
     1501 agctgatata acgtgccgac cagcggttgc ataaaatcct ggtaacggca ctgcttttcg
     1561 ctgatttgcg tcaaaacaga ttcccagtgc gcggtcatat ctggacgggc cgccatctcc
     1621 ggcagcgaat gtattaacgc tttgccagca tcggtagaat gaatgtagcg cccttttttg
     1681 gtcagaaagc tacgtttgaa cagcagttcg ataatcccgg cgcgcgtggc ttccgtcccc
     1741 agcccatcgg tcgcgcgcag gatctttttc agatctttat cctgcacgaa gcgggcaatt
     1801 ccggtcatcg cggaaagcaa tgtcgcatca gtgaaatgac gcggcggctg ggtttggcgt
     1861 tcgaccactt cccccttttc acacagcaac tcatcacctt tggcgacaac cgacagcggc
     1921 gtaccgtcgt tttcctcgtc gcgctcttta ctgcccagta acgtccgcca accggcctcc
     1981 gccagaaaac gcgctttggc gacaaatttc cctttggcga tttccagttc aataacgcat
     2041 ttacgaaaca ccgcgtccgg gcagaactgc atcagatact gacgcgcaat cagggtgtac
     2101 actttcgctt cgttttccgt cagatggaca gaagaactgc gcgccgtcgg gataatcgcg
     2161 tggtgcgcat ccactttttt gtcatcccag cagcgattgc gcgtatcagg attaaccaca
     2221 ggctgcggca gtaaatccgg ggcgtggacg ctaatcgcgt tcatgaccgc ctgccgtccg
     2281 gcaaagtgtt cttccggcag ataacggcag tcggaacgcg gataggtaat cagtttgtgg
     2341 gtttcatata gcttctgaca aatatcaagc acgttttgcg cgctcaggcc aaaacgttta
     2401 gcggcttcaa tctgtagcgt cgagagcgaa aacggcagcg gcgcggattc tgattcccgt
     2461 ttatcattat aactggttac cagcgcaggc tgaccgttga ttcggttcac cacatgctcc
     2521 gccagcggac gatgaagcaa acgcccctct tcatcctgat aaggttcgca cgcctcgctc
     2581 ggctgccaga tagcggtaaa acgctcgtcg gcaggcgtaa cgatgtgcgc cttcacttca
     2641 aagaagtctt tggcgacgaa gttctcaatc tcttcgtctc gccgcaccac cagccccagt
     2701 accggcgtct gcacgcgtcc cacggataac acgccctgat agccggcatt acggcccagg
     2761 atcgtgtaag cacgggtcat attaatgcca tacagccagt ccgctcgcgc tcgcgccagc
     2821 gcggagacgc acagcggcac gaagtcgctg ttcgcccgca gcctgtcgat agcacgctcg
     2881 accgcctgcg ggttaaggtc gtttatcaga caacgccgta cctgctggcg cttttcggca
     2941 ggaagctgga gataatccag cacttcatca accagaagct gcccttcgcg atccgggtcg
     3001 ccggcgtgaa taatttcacc ggcttgatgc aaaaagcgct taatcacatt gagctgtttg
     3061 gtgacggaag gacgaggctg aagctgccat ttttccggca cgataggcag gtcagccaga
     3121 ttccagcgcg cataacggct gtcatacgca tccggctgcg cctgttccag caaatgacca
     3181 atacaccagg tgacgacctg cccgtttccg cactcaataa aaccatcgcc tttacggtgc
     3241 ggttttggca gcacatccgc aatggcgcgc cccagactcg gtttttcggc aataaacaac
     3301 cgcatcaggt taacgaatct caaccatagc gcgaccgccg cgggcctcga ccagttcgcc
     3361 aatcgcggtc agttcgatac caaattccgc cgcggtggct ttaacatcgt cttcggcgtc
     3421 cggcgttacc gccaacagca gaccgcctga cgtttgcgga tcgcacagca ggctacgaac
     3481 ttcacgcgac atgtcgccca tcagatgacc atagctggcg aagttgcgct ctgtgccgcc
     3541 cggtacggcg cccagagcaa tatactcttc cacgcccggc agtttaggga tgtcctgata
     3601 gcaaagcatc gcctgtacgc ctgcaccctg gcacatctcg ctcaggtgtc ccagcagacc
     3661 aaaaccggta acgtcagtca tggcttttac gccgtcgata ttggcaaacg ccgcgccagc
     3721 aacgttcatc cgacacatga cttccgtcgc cagcccctga tgttcaggtt taagcagcga
     3781 ttttttctcg gcggtggtca acacgccaat ccccaacggt ttggtcagaa agagtttgca
     3841 tcccgcctgc gcggtactgt ttttcttcac ccgttcggtc ggcactacgc ctgtgaccgc
     3901 gagaccaaag atcggctccg gggcgtcaat agagtgtccg cccgccagcg cgataccggc
     3961 ctgacggcag gcaaaacgcc ccccctcggt cacttcacgc gcaatatcgg gcgacagggt
     4021 attaatcggc cagccaagga tcgcgatcgc cataatcggt ttgccgccca tcgcaaaaat
     4081 atcgctgatg gcgtttgttg ccgcaatgcg gccaaaatca aacgggttgt cgactatcgg
     4141 cataaagaag tcagtggtgc tgataatact ggtgccatta cccagatcgt aaactgccgc
     4201 atcatcgcgg gtttcattac ccaccagcag attcgggtcg acgaacttcg cctgctcgct
     4261 atgcaggata gtctccagca ctttagggga aattttacaa ccgcaaccag cgccgtggct
     4321 gtattgcgtt aaacgaatgg cttgcttgct catggacatc tcctgtcatt gcattcgcgc
     4381 tatggtagcg ctcattccct gatgtggtaa gtatcactgt ctgaattacc gcgcctttgc
     4441 tcagaatcca gacagtttta tccctcagcg tcagaaataa cgcacaaacg gcgtggggtc
     4501 gggggtactg atcgtcgttg acgctttgag ctgcggcgtg ccgagataga gaaaaccaac
     4561 aattttatcc tgaggacggc actcaaaggc ttcccgcacg atagcgctct ccgttaatgc
     4621 gccgctacgc cagataccat taaacccttg cgcaatcgct gccatttgca tcgccatcac
     4681 cgcgcatccg gcagacatct cctgttccca cacgggaacc ttatggtttt cttcgcattt
     4741 cgccaccacg gtaatgatca gcggcgcgcg aaacggcgca ttacgcgctt tttcgatcgc
     4801 tttctcatcc cccccggcag cgacagcgcc ttgttcaagc acggcgctga agcggtcgcg
     4861 cccctctcct tcaatcacaa aaaaacgcca cggctgtaga gatttatgat cgggaacacg
     4921 cattcccgcc cgcagaatgt tctgtaattg ctctccgaca ggcgccggtt ctgcgagacg
     4981 agaggcgctg cgacggttga ccagcagttc tagtgcatcc atttgattaa ctccagcaat
     5041 gatatttatt cacaaaatta acacgggagc ggattttgtt acagcgcagg cagtgattcc
     5101 tgctgacaac tgcctgatgg gtcattacga tagccacatc ttaatgcttt atcctcacca
     5161 aggtataagc gttgttactc agatagggag aatacatgcg aaccctgtgg cgatttattg
     5221 ccggattttt taaatggacg tggcgagtgt tgaacttcgt ccgtgaaatg gtactcaacc
     5281 tgttctttat ttttctggtc ctggtgggcg ttgggatctg gatgcagatc ggtaacggca
     5341 gcaacagtga gcaaacggcg cgcggcgctt tgctgctgga tatttccggc gtcattgtgg
     5401 ataaaccctc caccaatcac cgtctgggcg cgctgggacg ccagttattt ggcgccagct
     5461 ccgaccgtct gcaggaaaac tccctgtttg acatcgtcaa cgctattcgt caggcgaaag
     5521 atgaccgtaa catcacgggt atcgttctgg atctgaaaaa cttcaccggt gccgatcagc
     5581 cgtcaatgcg ctatatcggt aaagcgctgc gcgaattccg cgatagcggc aaaccggttt
     5641 tcgccgtggg tgaaaactac agccagggtc agtattacct cgccagtttc gccaataaaa
     5701 tttggctttc cccacagggt caggtagatc ttcacggctt cgctacgaat ggcctgtact
     5761 acaaaacgct gctggataaa ctgaaagtct ctacccacgt tttccgggtc ggcacctata
     5821 aatccgccgt cgagccgttt atccgcgacg atatgtcgcc cgccgcccgc gaggccgaca
     5881 gccgctggat aggcgaactg tggcagaact acctgcatac cgtttccgcc aatcgccaga
     5941 tttcgccgca acaactcttc cccggcgccc aggctattat cgacgggtta accagcgtgg
     6001 gcggtgacac cgccaaatat gcgctcgacc ataaactggt ggacgccctc gcctccagcg
     6061 cagatgttga aaaagcgctg acgaagcagt ttggctggag caaaaccgaa aataactatc
     6121 gcgcgatcag ctattacgat tattcgctga aaacgcctgc ggataccggc ggtactattg
     6181 cggttatttt cgccaatggc gcgattatgg atggcgaaga aacgccaggg aatgtcggcg
     6241 gcgacactac ggcatcgcag atccgcgacg cacgccttga tcctaaagtg aaagcgattg
     6301 tgctgcgcgt caatagccca ggcggtagcg tcaacgcctc cgaagttatc cgcgccgaac
     6361 tggcggcggc aagagcggct ggcaaaccgg tggtggtctc aatgggcggc atggcggcct
     6421 ccggcggtta ctggatctct acgccggcaa actatatcgt ggccagcccc agcacgctga
     6481 cgggttcaat tggcatcttc ggcgtaatta atacggtaga aaacagcctg tcgtcgattg
     6541 gcgtacacag cgacggcgtt tccacctcgc cgctggcgga tatttcgatg actaaagcgc
     6601 tgtcaccgga agtgcagcag atgatgcaac tcagtattga gtacggctac aaacgcttta
     6661 tcacgctggt ggcagacgcg cgtaagcgta cgccggagca gattgacaaa atcgctcaag
     6721 gccatgtctg gaccggagaa gacgcgaaag ccaatggtct ggtggacagt ctcggcgact
     6781 ttgacgacgc cgtcgccaaa gcggcggagc tggcgaaact gaaacagtgg catcttgatt
     6841 actatcagga cgaaccgaca gtccttgata tggtcatgga cagtatgacc ggatctgtac
     6901 gcgccatgct gccggaggcc attcaggcga tgctcccggc gccgctcgtt tccgccgcca
     6961 acacggtgaa ggccgagggg gataaactgg cggcatttaa cgatccacaa aaccgttatg
     7021 cgttctgttt gacttgcgcg aacgtgcgct aatgcttcat caatagccat accggatgtc
     7081 ggcgtctgct catagccgcc atccgataat cattaatacg tccttcgcga cacgactgaa
     7141 cattatcatg caaaagaaat caatttacgt tgcctatacc ggcggtacta tcggtatgca
     7201 gcgctccgat aaagggtata tcccggtgtc cgggcgcctt cagcgtcagc tggcgctgat
     7261 gccggaattc caccgcccgg agatgccgga ttttaccatc catgaatatg ccccgctgat
     7321 ggattcatca gatatgacgc cggaagactg gcagcatatc gctgcagata tcaaagcgca
     7381 ctacgatgag tatgacggtt ttgttattct gcacggcacc gacacgatgg cgtataccgc
     7441 atcggcgctc tctttcatgc tggaaaatct gggtaaaccg gttattgtga cagggtcaca
     7501 aattccgctg gctgagctgc gctccgacgg gcaaattaat ttgctgaatg cgctttatgt
     7561 cgccgccaac taccctgtta atgaagtaac gctgtttttt aataatcgtc tgttccgcgg
     7621 caatcgcacg accaaagcac atgcggatgg ttttgacgct tttgcctctc ctaatctgcc
     7681 gcccttgctg gaagcaggaa ttcacattcg ccgtttaaat acgcctcccg cgccctacgg
     7741 ttctggtgaa ttaatcgttc accctattac gccgcagccg ataggcgtag tgacgattta
     7801 tccggggatt tccgccgagg tagtacgtaa ctttctgcgt cagccggtaa aagcgctgat
     7861 tctgcgctct tatggcgtag gcaacgcgcc gcaaaataaa gcgtttttac aggagctgaa
     7921 agaggccagt tcgcgcggca tcgtggtggt taacctgacg caatgcatgt cagggcgagt
     7981 caatatgggc gggtacgcta ccggtaatgc gctggcgcac gctggcgtga ttggcggtgc
     8041 cgatatgacc gtcgaagcta ccttaaccaa actgcattat ttgttaagcc agggtctgga
     8101 cactcaggcg attcgtagcg cgatggcgca aaacttgcgt ggtgaattga cgccggatga
     8161 ttaaaaaatc ccgacgacaa ggagaagata atgacaaacc gggccttatt actggtcgac
     8221 ttgcaaaatg acttttgtgc cggcggcgcg ctggctgtag cggaaggcga cagcaccatc
     8281 gacatcgcca acgctcttat tgactggtgc cagccccggc agattccggt gctggccagc
     8341 caggactggc atcccgcgca gcatggcagc ttcgccagcc agcatcaggc ggaaccctat
     8401 agacagggaa agctggacgg gctgccgcaa acgctctggc cggatcactg cgttcaacat
     8461 accgacggcg cggcgttaca tcccctgctt aaccaacatg cgattgacgc ctgcatctat
     8521 aaaggtgaaa acccgctgat tgatagctac agcgcgtttt ttgacaacga acatcggcag
     8581 aaaactaccc ttgatacctg gcttcgcgag catgacgtta ccgagcttat cgtgatgggg
     8641 ttggcgaccg attactgcgt aaaatttacg gtgctggatg cgctagagtt gggctatgcc
     8701 gttaacgtta tcaccgatgg ctgtcgcggc gtgaatattc acccgcagga tagcgcacac
     8761 gcgtttatgg agatggcggc ggcaggcgcg acgctgtata cgctggcaga ctgggaagag
     8821 acgcagggcc aggctatcgc caggtagcgg agcaggtatc gtatccggtc aatacatcac
     8881 gcaacggtga gaccattgca tagatctttg ggccggatac gtcacgtcag cgtcgctacc
     8941 aggcaaagct caacgcaggc tggagagcgc ttctaacgaa acagattaaa aagcgcgggc
     9001 tggccggcgc aatgttctgg gaataggccg ccaatgacaa taatcagtta gcgaaacagt
     9061 tggcggactc gctggacatt aagcgtaatg ggtaaaaata tggcgggcct gtgcctgaca
     9121 gcaatgagca ggcccggtaa gcacaacgca ttggcaatta aaccaccgga tggcgactac
     9181 ctcttatccg gctgccgtta ctgcattttc aatgtcgcaa tcggctttga cgtaataccg
     9241 aaatccgctt tgagctgctg cttgcttttc atcaccatct gaccgtgagt atcgatcgtc
     9301 atatgttgcg cttcggtatt gtgccgcgcc tgccatagca tcaccagttg caggctgttt
     9361 tctttctgtt ccggcgtcaa cgccacgcca tccggccatt tacccagctc aacggcggtg
     9421 gataaacgtt gatacacttc cggcgtcatg ctgttaatga tctcatcaag attcatgatg
     9481 tgtccgctcc tgtggaataa tttgctgaat cgttttttca gcctttcagt tgatcgccgt
     9541 ttttctcgtc agaaaaggcc agcgaggccg agttaacgca atagcgctca ccggttggct
     9601 gcggcccgtc cgggaaaacg tgtccgagat gcgcatcgca gttaccgcaa cgaatttcga
     9661 cacgctgcat gccatgagaa aaatcgtcta tgtaacgaat cgcctcttcg ctgacaggct
     9721 ggtaaaagct aggccagccg cagcctgaat cgtatttggt gtgggagtga aaaagcggcg
     9781 tatcacagac caggcagtga taaaccccat cgcgtttatt atgtagcagg cgtccggtaa
     9841 atggcggttc tgtgccacga tcctgcgtca catagaattg catttcggac aattttttct
     9901 tgagttcttc tgctgaaggt tggttagcca tttgctcaca tctcacttta aacgtgctca
     9961 cattgcctga ccgattctaa caaaacatta gcacctcagt accaactttt gttctaaact
    10021 tgatcattgc gaaatggcgg ctcacgaatc gtgactgatg tcacattatt atctcggttg
    10081 ccctttaaaa ttcggggcgg cgcccccatg tggtttcaag ctgaaaggaa gagtgaggcg
    10141 aatcagccgc gcaaaggttg tgcagaggat tgatttgtcg caatgattga cacgattccg
    10201 cttgacgctg cgtaaggttt ttgtaatttt acaggcaacc ttttattcac taacaaatag
    10261 ctggtggaat atatgactat caaagtaggt atcaacggtt ttggccgtat cggtcgcatt
    10321 gttttccgtg ctgctcagaa acgttctgac atcgagatcg ttgcaatcaa cgacctgtta
    10381 gacgcagagt acatggcata catgctgaaa tatgactcca ctcacggccg tttcgacggt
    10441 actgttgaag tgaaagacgg tcatctgatc gttaacggta aaaaaatccg tgttaccgct
    10501 gaacgcgatc cggctaacct gaaatgggac gaagttggtg ttgacgtagt ggctgaagct
    10561 accggtatct tcctgactga cgaaaccgcg cgtaaacaca tcaccgctgg cgcgaaaaaa
    10621 gtggttctga cgggtccgtc taaagacaac accccaatgt ttgttaaagg cgctaacttt
    10681 gacaaatacg aaggccagga catcgtttcc aacgcttcct gcaccacaaa ctgcctggcg
    10741 ccgctggcta aagttatcaa cgacaacttc ggcatcatcg aaggtctgat gactactgtt
    10801 cacgcgacta ccgcaaccca gaaaaccgtt gacggcccgt ctcacaaaga ctggcgcggc
    10861 ggccgcggcg catctcagaa catcatcccg tcctctactg gcgctgctaa agcggtaggt
    10921 aaagtactgc cggaactgaa tggcaaactg actggtatgg cgttccgcgt tccgactccg
    10981 aacgtatccg ttgttgacct gaccgttcgt ctggaaaaag cggctaccta cgagcagatc
    11041 aaagctgctg ttaaagctgc tgccgaaggc gaaatgaaag gcgttctggg ttacaccgaa
    11101 gacgacgttg tatctaccga tttcaacggc gaagtatgca cttccgtgtt cgatgctaaa
    11161 gcaggcatcg cgctgaacga caacttcgtg aaactggtct cctggtacga taacgaaacc
    11221 ggttactcca acaaagtact ggacctgatt gctcacatct ccaaataagt tgagatgaca
    11281 cagtcattgg taagagcgac tcaggtcgct cttttttttg cttaaagata tacccgtcat
    11341 acttcaagtt gcaggtgtgt tggctatgct ttctcacccg aatcactgac ggaagtcgaa
    11401 cttatcggga tgaatcaggg atgcccctga ccgaaggtta cctacggttg ttcaaattcg
    11461 ttcccgatga atttgtcgtt cacttgccgc gttactcggc ctgcggcctc gcctctacgg
    11521 gccagcgcaa gcactggtca aggcacaagc gccttgtcat gcaactcgaa ttatttaggg
    11581 ttaagaggat tgcgtaatga ttaataaaat ttttgccctc ccggttatcg aacagcttac
    11641 ccctgtcctt tcccgtcgtc agcttgatga cctggatctg atcgtcgttg accatccgca
    11701 ggttaaagcc tcttttgcat tacagggcgc gcaccttctc tcctagaaac ccattggcga
    11761 ggaagaggta ttgtggctca gtaataatac gcctttcaaa accggcgtgg cgctacgcgg
    11821 cggcgtaccg atctgctggc cctggtttgg acctgcggct caacagggtc tgccgtcaca
    11881 cggctttgcg cgtaatcttc cgtgggcgct aaaagcgcat aatgaagatg ataatggcgt
    11941 aatgctgaca tttgagctgc aaagcagtga ggccacccgg aaatactggc cgcacgattt
    12001 cacgctgctg gcacgtttta aagtgggtaa aacctgtgaa attgaactgg aagcgcatgg
    12061 cgaatttgca accacatccg cgctccacag ctattttaac gttggcgaca tcgccaacgt
    12121 taaggtcagc ggactcggcg atcggtttat tgataaagtt aacgacgcta aagaagatgt
    12181 cctagccgac ggtatacaaa cctttccgga ccgtaccgat cgcgtttacc tcaatcctga
    12241 agcatgtagc gtgatccacg atgcgacatt aaaccgcacg attgatgtgg tccaccacca
    12301 tcaccttaac gtcgtaggct ggaaccctgg cccggcgttg tccgtcagca tgggcgacat
    12361 gccggatgac ggctataaaa cgtttgtctg cgttgaaacg gtttacgcta ctgcgccgca
    12421 acaagccaca gaagaaaaac cctctcgtct ggcgcagact atctgcgtcg ctaaacgcta
    12481 aaagtgaatg gataacggcg ttgctatagg ctctggaagg cgccagccgc catcaggcat
    12541 gacctgccgg atggcggcac ttacacattt tatccggcgt cacaccatat ccaacgcggt
    12601 tttccctttt ggcgcaggcc aggcgttgtc cagtaaggca agttcgtttg ctgacaaggt
    12661 aatctcaagc gccgccgcat tttgcttcac gtgttctgta cttccggctt tcgggatcgc
    12721 catcacgccc ggatgcgcaa tcacccacgt cagtaagatt tgcgccgccg ttgcgttatg
    12781 cgcttgcgca atttcattca ccaccggatg attcagtaaa ccgctacgta accggccagc
    12841 ctgcgccagc gggctatagg ccatcactgg cattcgctgt tgttgacacc acggcaataa
    12901 atcatactca ataccgcgtg acgccagatg atagagcacc tgatttgtcg cgcattgctg
    12961 tcccccaggg atgcgccaca gcgcctgcat atcgtcataa tcaagattag agactcccca
    13021 acggcgaatt tttccctgcg cgattagccg ctccatacct tcaacggtct cttcgaatga
    13081 aaagcctccg gcccagtgca atagatagag atcgagataa tctgttttca gacgacgcag
    13141 gctttcctca caggcggcaa ctatcttctg gccgccagcg ttccacgggt acacttttga
    13201 cactagaaat gcctcatcgc gtcgccctgc taacgcctcg cccacgacct tttccgcccc
    13261 gccgtcggca tacatttccg ccgtatcaat aaggcgtaac cccaaatcca gccccgcgcg
    13321 cagcgccgaa acctcgcgct gacgttgatc cgcgcgctcg cccatatacc atgttccctg
    13381 tccgatggca ggaagcgtca cctgcccgca aaacgttacg tttttcactg atttcatttc
    13441 cttttcaatt tcactcgacg gtaaaacaat acaggactct tagaccctac ggtaatgtcc
    13501 ggcatcatac cgcgcaaggg gggcgatttt cttgtcactg acgaacgtca tccgcaatca
    13561 tgtcgacgat gcgggtaata tgcgcggcgg gtcgctgatt cagtaataat tgacgcatca
    13621 cattcatata gggcgtcaca tgttgaaaga actccagata tcctttacag agataatttt
    13681 gccgttcgcc gccgtccata caaattcgat gtttcggaca accgccgtga caggcaaagc
    13741 gccacgtaca gttctggcag cgtgaagaaa ggtttgcttt agccgcgcca aactgctgct
    13801 gaaaaggaga ggccgccatt tcttctaaag agtgttgctg cagattgccc agtttatagg
    13861 cgggaaaaac aaaatggtca cagctaaaca cgtcgccatt ctgctccacc agcaaacttt
    13921 gcccgcaggt cgactgcatc gtacaaagcg tggcgggctc ccccatccag acgccaagta
    13981 agttatcaaa aagctgtacg aatatgcgtc cgacatcgtg acgtatccat tgatcaaaaa
    14041 catcgcacat aaaggccccc cacccttcag gcgtgacgga aaagggcatc agcgaaggcg
    14101 aatcttcatt gtcagataac gtcaaagaac gctgcgcttt ttgcgcgagc ggctcaacaa
    14161 tgggaataaa ttgtaggtgt ttactttcca gttcctgcgt caaaaaatga taaatagcgt
    14221 tgccatgacg gcatgatgca tcattcacga cagtgagcgt attgaactcg acatcatttg
    14281 cctgcagaag gcggatagca ttaacgactc gggaaaaaga cgcccgccct gacggcgttc
    14341 tccggtaatt atcatgaacg acttgcggcc catcaatcga tataccaatc aggaactggt
    14401 gctgcacaaa gaaagccgcc cactcttcat tgattaatac gccattggtt tgcagactgt
    14461 tgtaaatagt tttgccgttg gcatagcgtt gctgcaagca caccactttt tgataaaaag
    14521 aaagaccgca tagcgtcggc tctcccccct gccaacaaaa cgagacctct gatgatggcg
    14581 tatcatcaat tacccggcgg atatacgtct ccagcacatc gtcagacatg acgcgctggc
    14641 cccggggttt atcaagatag aaacagtact tgcaggataa gttacacaga ctgccgctgg
    14701 gcttggccac ggtattgaat actatgctca ttcgtcttac tcgctgtgaa gaatgggtat
    14761 agcataagcg ggacgtgaca gggcgatatc agccagcatt gcaacaatta ttacgctaat
    14821 tgttagcgca gttgtaatca cctggatttt tcatataaaa ggctagtttt ttaaattgat
    14881 gtaacaaagt ataaatcacg taaggctgcg ccatacccgg tcaacagcgc atttatgcaa
    14941 gccgccatgt tcgcgtttca gacagcacaa agcccgcata acgcaggctt tgtcatggtt
    15001 tttccggcaa attcaatcaa tcagaatcta taggtcacgc cagtagaaag gataccggtc
    15061 caggatttat ccaccatcgg gctgtcggta atttcatccg acaggcgggt gtagcgcgca
    15121 gtaccatata cgctccagtt accggcgaaa ttatagttag cgctcagttc aagatacggg
    15181 ttccagctat cgttcgggtt atagccgcgc aggccgctac gcgaagattc tttacgtgat
    15241 acgccgtaat agtaatcgtt ctggttctcg ctattccatt caaccccgat acctggcgtt
    15301 aaggtcagcc cgccattggt ataccgatac agccaggcca gatcccagac aataccgtta
    15361 ctgttatcta acgtatcccc tgccagtgag gtacgcagga atccatactg ggtgtggtgc
    15421 gcgtaagaaa cgcccgccat catagtactt ttacgcctgt ccagacgacg caactgatgg
    15481 tcatcgctgt cgcccggttt gaagtacatc ggggaccagt atgccatgat tgacaactta
    15541 tcggcattgt cattccacaa gtagtacccg ccgcccagac cacggaacca gaagttttcg
    15601 ctttcataag cgatgaccgg tatcggataa acatcgctat cgtaatcttt ataagggtgt
    15661 tcaaccacac caacgcctgc gcccaacgtc aggttgcttt cagcgtgcgc gacgctggcg
    15721 gatgttgcaa taaacacgcc aagagccaga agtttaagtt tggtcacaat ccataattcc
    15781 ttattcaaat gttctgcggc aaaagtgtaa ccgccaatac ctgtaagccc aactatttta
    15841 cacaatgtaa ccgtttaata tcaccatcac cgattatttt cagatgatcg gctgatgatc
    15901 gttatgtggc cgggaacgct ttttctgata tccaccagcc ttttctacct gatgagttat
    15961 tgatatgtca tcgaaattca ctgacgcgta caggcaagtt ttgcaaatgc catctacgct
    16021 taatgttaag aaggtgtatc accggacacg ttgatcttct gaccaataaa atggcatgag
    16081 agttgctttt tttccttagc agagacggcg ttcagtctac ctcttccggg agcctctact
    16141 attcatatga acggctctta acatgtgcga aaaaacgaaa gaatggcata tcatgaatat
    16201 attcgatcac tatcgccagc gttacgaagc tgccaaggac gaagagttca cactgcagga
    16261 ttttcttacc atttgtcggc aagatcgcag tgcttatgcc aacgcggcag agcggctatt
    16321 aatggctatc ggcgagccta atatggtcga cactgcccag gaaccccgac tttcccgact
    16381 cttctccaac cgggttattg ctcgctatcc tgcgtttgaa gagttttacg gcatggaaga
    16441 cgcgattgaa cagattgtct cttatctgaa acatgcggcg caagggctgg aagagaagaa
    16501 gcaaattctc tatttgctgg gacctgtggg gggtggcaaa tcatcgctcg ctgaacggct
    16561 gaaatcgcta atgcagcgcg tgccaattta tgttttaagc gccaacggcg agcgtagtcc
    16621 ggtcaacgat catccgttat gcctgtttaa tccgcaggaa gacgcgcaga ttctggaaaa
    16681 agagtacggt attccgcgcc gctatctcgg tacgattatg tccccgtggg cggccaaaca
    16741 cctgcatgag tttggcggcg atattactaa attccgcgtg gtgaaagtct ggccctccat
    16801 tctggagcag attgccatcg ccaaaacgga acccggcgat gaaaacaacc aggatatttc
    16861 ggcgctggtc ggcaaggtgg atattcgtaa actcgaacat cacgcccaga acgatccgga
    16921 tgcgtatggt tactctggcg cgctatgccg cgctaaccag gggatcatgg agttcgtcga
    16981 gatgtttaaa gcgcctatta aggtgctgcc ccccttgctg accgcaactc aggaaggtaa
    17041 ctacaatggt acggaaggta tttccgccct gccctttaat ggcatcatac ttgcccactc
    17101 aaacgaatct gaatgggtga ctttccgtaa caataaaaat aacgaagcgt tcctcgaccg
    17161 tgtctatatt gtgaaggtgc cttattgcct gcgaatctcc gaagagatca aaatctacga
    17221 gaaactactt aatcatagcg agctggctca tgcgccctgc gcgccgggca cattggaaac
    17281 gctttcgcgc ttctcgactc tttcccgcct gaaagagccg gaaaattcca gtatttactc
    17341 gaaaatgcgc gtttatgacg gtgaaagcct gaaagatacc gaccccaaag ctaaatcgta
    17401 ccaggagtat cgcgactatg cgggtgtgga cgaagggatg aacggtctct ccacccgatt
    17461 cgcctttaag atcctctccc gcgtattcaa cttcgaccat gcggaagtgg cggcaaaccc
    17521 ggtacatctg ttctacgttc tggaacaaca aatcgagcgc gagcagttcc cgcaggagca
    17581 agctgagcgt tatctggagt tcctgaaagg ctacctgatc ccgaaatacg ccgaatttat
    17641 cggcaaggag atccagacgg cctatctcga atcttactct gagtacgggc agaacatttt
    17701 tgatcgttac gtgacttatg cggatttctg gattcaggat caggagtatc gcgacccaga
    17761 taccggtcaa ctgttcgatc gcgagtcgct gaacgccgaa ctggaaaaaa ttgaaaaacc
    17821 agcgggtatc agtaacccga aagatttccg taatgagata gtaaactttg tcctgcgcgc
    17881 cagagccaac aatagcggcc gtaatccaaa ctggaccagt tacgagaagc tgcgcacggt
    17941 gattgagaaa aaaatgttct ctaatactga agagctgttg ccggtcattt cttttaacgc
    18001 caaaacgtcg actgacgagc agaaaaagca tgacgacttt gtcgatcgga tgatggaaaa
    18061 agggtatacc cgtaagcagg ttcgtttgct gtgcgagtgg tacctgcgcg tgcgtaaatc
    18121 gtcgtgatgt taatgcccgg tggcgcttgc gcttaccggg cctacaaagt aatgttctgt
    18181 agactggcta agcgttagcg ctatccggca ctaacagaac aggcgctcag ttggcagtac
    18241 ggggggcata tgacctggtt catagaccga cgtcttaacg gcaaaaataa aagcacggtg
    18301 aatcgccagc gctttttgcg tcgttataaa gcacaaatta agcagtcgat ttccgaagcg
    18361 attaataaac gctcagtgac cgatgtcgac agcggagagt ccgtctctat tccaaccgat
    18421 gatattagcg aaccgatgtt tcatcagggg cgcggcggtc tgcgccatcg cgtccatccg
    18481 ggtaacgatc actttatcca gaatgatcgc attgagcgtc cgcaaagcgg tggcggcggc
    18541 ggttccggca gcggtcaagg tcaggccagc caggacggcg aaggccagga tgagtttgtt
    18601 tttcagattt caaaagatga gtatctggat ctgctctttg aagatttagc gctgcctaat
    18661 ctgaaaaaaa accagcatcg ccagcttaac gagtataaaa ctcaccgcgc cggtttcacc
    18721 tcaaacggcg tgccggccaa tatcagcgtg gtacgttcgc tacaaaactc tctggcgcgc
    18781 cgtacagcaa tgacggcagg aaaacgccgc gaactgcacg cgctggaaac ggaactggag
    18841 accatcagcc acagcgaacc agcgcaactg cttgaagagg agcggttacg tcgggagatt
    18901 gccgaactac gggctaaaat cgagcgagtg ccgtttatcg acacttttga tttacgctat
    18961 aaaaattatg aaaaacgacc tgagccctcc agccaggcgg tgatgttctg tctgatggac
    19021 gtctcgggtt cgatggacca ggcaaccaaa gatatggcca agcgttttta cattctgctt
    19081 tatctgtttt tgagccgaac gtataagaac gtagaagtgg tttatatccg ccaccatacc
    19141 caggcgaagg aagtggatga acatgagttc ttttattcgc aagagaccgg ggggacgatt
    19201 gtctccagcg cgcttaaact catggacgaa gtagttaaag agcgctacga ccccagtcag
    19261 tggaacatct atgcggcgca agcgtcagac ggtgataact gggccgacga ttcaccgctg
    19321 tgtcatgaga ttctggcgaa aaagctgctg ccggtagtgc gctattacag ctatatcgag
    19381 attacccgcc gcgcccacca gaccttatgg cgcgagtatg aacatctgca ggcgacgttc
    19441 gataacttcg ccatgcagca tattcgcgat caggaggata tttatccggt attccgcgaa
    19501 ttgtttcaga aacagagcgc caatcaaagt gcataaccct aaatcagccc gtaatgcgtc
    19561 acgggctgat ttatcactaa caaggcgatt atacatattg ccactacaat agccgtaaac
    19621 ctgtatatct cctgactgga tttaccttac atgcgccgac ttatcactgg aatagtatgg
    19681 atttattaat gccagcaata ctcaccagga ggtggcggta attgcagaga atcagggggt
    19741 tgtagtttgc aaaaaaagta gtgaccagga aaatagatat caaaatccca cgggccacca
    19801 ccactgcccg acgatgccat agccgacgac gtgaacccca cggccagcaa tgcaaaaagc
    19861 aaaattgctg ctatttcttt aaatcgtttc atagtacctc cgaacggaag tacattatta
    19921 tccttaccac gtcacactcc tttcacgtaa taataaaggc tattttattt tcgttagtgt
    19981 taaatcgatg ccgttaatta acaatttact ttttgcgaca atagtcacga ctgaaaatat
    20041 caacaccata tattattgaa tttattaaat cgagaatgat ttttattcca taacatcaac
    20101 acgttttatt tttaaacagt ctgttagagg aattctcatc gctatggtaa actaacgcat
    20161 ccgactttca gggctgtagt tcatcatgaa tttgcatcat aaagcgctca ggcactttat
    20221 ctcggcaagc gtcatcgttt tgacatcgtc cttcctgatt tacgaactta ttgccagcga
    20281 cagggcaatg aatgcctata tgcgttatat catggagaga gccgattcgt cgtttttgta
    20341 cgataagtac cagaattaaa gcatcgccgc acatttgatg cgaacttttg aagcgccggg
    20401 agaccccgtc accgcagaaa aacgccgcgc gttttgcgac gcctttgagg ccattaacgg
    20461 tacgcacggc gtcaacctga cccggcataa ttatccggcg ctacatggca ccctgcaaac
    20521 cgtcgctaca cagtgtaccg ataatcttga tgacgccctt ttactgcctg catttgatca
    20581 ggcggtaagc atcaaccgag cgcaggacga ccacagtcac gggctgggca cactggagct
    20641 taaattccgt tattacgttg atttaaataa acattat
//
LOCUS       DAJVBX010000067        20487 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.067, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000067 DAJVBX010000000
VERSION     DAJVBX010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 20487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20487
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.067"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(124..639)
                     /gene="mobB"
                     /locus_tag="OPV72_002097"
     CDS             complement(124..639)
                     /gene="mobB"
                     /locus_tag="OPV72_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="HCR9914395.1"
                     /translation="MIPLLAIAAWSGTGKTTLLKKLIPALCAHGIRPGLIKHTHHDMD
                     VDKPGKDSYELRKAGAAQTLVASQQRWALMTETPGQEELDLAWLVSRMDASKLDLVLV
                     EGFKHEAVAKILLFRQGCGHSEEELILDEHVIAVASDIPLAVAVPVLDLNDVSQISAF
                     ILRWLEKARSL"
     gene            complement(636..1220)
                     /gene="mobA"
                     /locus_tag="OPV72_002098"
     CDS             complement(636..1220)
                     /gene="mobA"
                     /locus_tag="OPV72_002098"
                     /EC_number="2.7.7.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase MobA"
                     /protein_id="HCR9914396.1"
                     /translation="MNLDEVITGVVLAGGKARRMGGADKGLLELDGKPLWRHVADALA
                     PQLATVVISANRHLDIYQASGLKVIPDSIADFPGPLAGMLSVFQQVAGDWFLFCPCDN
                     PCIPHNLVDRLAAHRHGAPVVWVHDGERDHPTIALINRAVEPQLTAYLQAGERRVMIF
                     MRQVGGHAVDFSDCKEAFVNVNTPEELAQWQKRP"
     gene            1290..1559
                     /locus_tag="OPV72_002099"
     CDS             1290..1559
                     /locus_tag="OPV72_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015966571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihD family protein"
                     /protein_id="HCR9914397.1"
                     /translation="MKCKRLNEVIELLQPAWQKEPDLNLTQFLQKLAKESGFDGKLED
                     LTDDILIYHLKMRDSAKDAAIPGIQKDYEEDFKTALLRARGVIKE"
     gene            1636..2622
                     /locus_tag="OPV72_002100"
     CDS             1636..2622
                     /locus_tag="OPV72_002100"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein kinase"
                     /protein_id="HCR9914398.1"
                     /translation="MNDNAFTFQTLHPETIMDALFEQGIRVDSGLTPLNSYENRVYQF
                     QDEDRRRFVVKFYRPERWSVDQIREEHQFALELVKDEVPVAAPLAFNGQTLLAHQGYH
                     YAIFPSVGGRQFEADNIDQMEAVGRYLGRLHQTGRKRPFTFRPDIGLAEYLFEPRQVF
                     EDAALIPSGQKAAFLKATDTLLSAVTECWRTDFATLRLHGDCHAGNILWRDGPLFVDL
                     DDARNGPAIQDLWMLLNGNKAEQRMQLETIIEAYEEVSEFDTAEIGLIEPLRAMRLVY
                     YLAWLIRRWGDPAFPKNFPWLTGEDYWQRQTTTFIEQTKILHEPPLQLTPMY"
     gene            2639..3262
                     /gene="dsbA"
                     /locus_tag="OPV72_002101"
     CDS             2639..3262
                     /gene="dsbA"
                     /locus_tag="OPV72_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbA"
                     /protein_id="HCR9914399.1"
                     /translation="MKKIWLALAGMVLAFSASAAQISDGKQYITLDKPVAGEPQVLEF
                     FSFYCPHCYQFEEVLHVSDNVKKKLPKGTKMTKYHVEFLGPLGKELTQAWAVAMALGV
                     EDKVTVPLFEAVQKTQTVQSAADIRKVFVDAGVKGEDYDAAWNSFVVKSLVAQQEKAA
                     ADLQLQGVPAMFVNGKYQINPQGMDTSSMDVFVQQYADTVKYLVDKK"
     gene            complement(3275..4183)
                     /locus_tag="OPV72_002102"
     CDS             complement(3275..4183)
                     /locus_tag="OPV72_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HCR9914400.1"
                     /translation="MTRILAAITLPLSIVLTILVTIVCSVPIIVAGMVKLLLPVPGIW
                     RKVSIFCNFMMYCWCAGLAALLRLNPHLQWDVEGLEGLSKKNWYLLICNHRSWADIVV
                     LCVLFRKHIPMNKYFLKQQLAWVPFIGLACWALDMPFMKRYSRSYLLRHPDRRGKDVE
                     TTRRSCEKFRRYPTTIVNFVEGSRFTHEKRQQTHSPYQHLLPPKAAGIAMAINVLGSQ
                     FDKLLNITLCYPNNDRHPFYDMLSGRLTRIVVRVQLEPINEELHGDYVNDKTFKRRFQ
                     RWLNTLWDKKDIQIEEIKTSYKNAGQ"
     gene            4571..7357
                     /gene="polA"
                     /locus_tag="OPV72_002103"
     CDS             4571..7357
                     /gene="polA"
                     /locus_tag="OPV72_002103"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HCR9914401.1"
                     /translation="MVQIPENPLILVDGSSYLYRAYHAFPPLTNSAGEPTGAMYGVLN
                     MLRSLIMQYQPTHAAVVFDAKGKTFRDELFEHYKSHRPPMPDDLRAQIEPLHAIVKAM
                     GLPLLAVSGVEADDVIGTLAREAEKVGRPVLISTGDKDMAQLVTQNITLINTMTNTIL
                     GPDEVVNKYGVPPELIIDFLALMGDSSDNIPGVPGVGEKTAQALLQGLGGLDTLYAEP
                     EKIAGLTFRGAKTMAGKLAQNKDVAYLSYKLATIKTDVELELTCEQLEVQQPIADELL
                     GLFKKYEFKRWTADVEAGKWLQAKGAKPAAKPQETVVIDESPSEPAAALSYENYVTIL
                     DDVTLESWIEKLKKAPVFAFDTETDSLDNIAANLVGLSFAIEPGVAAYVPVAHDYLDA
                     PDQISRQRALELLKPLLEDEKVRKVGQNLKYDRGVLQNYGIELRGIAFDTMLESYILN
                     SVAGRHDMDSLSDRWLKHKTITFEDIAGKGKNQLTFNQIALEEAGRYAAEDADVTLQL
                     HLKMWPELQQHKGPLNVFENIEMPLVPVLSRVERNGVKIDPAVLHKHSEEITLRLAEL
                     EKKAHDIAGEAFNLSSTKQLQTILFEKQGIKPLKKTPGGAPSTSEEVLEELALDYPLP
                     KVILEYRGLAKLKSTYTDKLPLMINPKTGRVHTSYHQAVTATGRLSSTDPNLQNIPVR
                     NEEGRRIRQAFIAPEDYLIVSADYSQIELRIMAHLSRDKGLLTAFAEGKDIHRATAAE
                     VFGLPLDSVTGEQRRSAKAINFGLIYGMSAFGLSRQLNIPRKEAQKYMDLYFERYPGV
                     LEYMERTRAQAKEQGYVETLEGRRLYLPDIKSSNAARRAGAERAAINAPMQGTAADII
                     KRAMIAVDAWLQAEQPRVRMIMQVHDELVFEVHKDDLDAVAKRIHQLMENCTRIDVPL
                     LVEVGSGENWDQAH"
     gene            complement(7693..8325)
                     /locus_tag="OPV72_002104"
     CDS             complement(7693..8325)
                     /locus_tag="OPV72_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HCR9914402.1"
                     /translation="MTNLNYQQTHFVMSAPDIRHLPSDCGIEVAFAGRSNAGKSSALN
                     TLTNQKSLARTSKTPGRTQLINLFEVVDGKRLVDLPGYGYAEVPEEMKRKWQRALGEY
                     LEKRQSLQGLVVLMDIRHPLKDLDQQMIQWAVESNIQVLVLLTKADKLASGARKAQLN
                     MVREAVLAFNGDVQVEAFSSLKKQGVDKLRQKLDSWFSELAPVEEIQDGE"
     gene            8565..8789
                     /locus_tag="OPV72_002105"
     CDS             8565..8789
                     /locus_tag="OPV72_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914403.1"
                     /translation="MSLPQKSKVMHIARTLTGSTTQDEGQERQEAKTQDCQEDKRPET
                     LVKGNGNNMECSRLREKQGVLIANRDGGTR"
     gene            8908..9423
                     /gene="yihI"
                     /locus_tag="OPV72_002106"
     CDS             8908..9423
                     /gene="yihI"
                     /locus_tag="OPV72_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Der GTPase-activating protein YihI"
                     /protein_id="HCR9914404.1"
                     /translation="MKKPTSAPRSKAFGKQRRKTREELNQEARDRKRLKKHRGHAPGS
                     RAAGGNSASGGGNQNQQKDPRIGSKTPVPLGVTEKVTQQHKPKSEKPMLSPQAELDLL
                     ETDERLDALLERLEAGETLSAEDQAWVDAKLDRIDELMQKLGLSYDDDEEDDEEDEKQ
                     EDMMRLLRGGN"
     gene            9612..10985
                     /gene="hemN"
                     /locus_tag="OPV72_002107"
     CDS             9612..10985
                     /gene="hemN"
                     /locus_tag="OPV72_002107"
                     /EC_number="1.3.98.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HCR9914405.1"
                     /translation="MSEQQIDWDLALIQKYNYSGPRYTSYPTALEFSEDFEDAAFLQA
                     VARYPERPLSLYVHIPFCHKLCYFCGCNKIVTRQQHKADQYLDALEQEIRHRAPLFAD
                     RHVSQLHWGGGTPTYLNKAQISRLMTLLRENFHFNTDAEISIEVDPREIELDVLDHLR
                     AEGFNRLSMGVQDFNKEVQRLVNREQDEEFIFALLNHARDIGFTSTNIDLIYGLPKQT
                     PESFAFTLKRVTELNPDRLSVFNYAHLPTLFAAQRKIKDADLPSAQQKLDILQETIVS
                     LTQAGYQFIGMDHFARPDDELAVAQREGVLHRNFQGYTTQGDTDLLGMGVSAISMIGD
                     GYMQNQKELKRYYQQVDERGNALWRGITLTRDDCIRRDVIKALICNFRLDFNAVEQQW
                     GLHFAEYFAEDLQLLSPLAKDGLVDISEKGIQVTAKGRLLIRNICMCFDAYLRQKARM
                     QQFSRVI"
     gene            complement(11075..11185)
                     /locus_tag="OPV72_002108"
     CDS             complement(11075..11185)
                     /locus_tag="OPV72_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YshB family small membrane protein"
                     /protein_id="HCR9914406.1"
                     /translation="MLESIINLVSSGAVDSHTPQTALAAVLCAALVGLFS"
     gene            complement(11298..12707)
                     /gene="glnG"
                     /locus_tag="OPV72_002109"
     CDS             complement(11298..12707)
                     /gene="glnG"
                     /locus_tag="OPV72_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen regulation protein NR(I)"
                     /protein_id="HCR9914407.1"
                     /translation="MQRGIVWVVDDDSSIRWVLERALAGAGLTCITFENGNEVLAALA
                     SKTPDVLLSDIRMPGMDGLALLKQIKQRHPMLPVIIMTAHSDLDAAVSAYQQGAFDYL
                     PKPFDIDEAVALVERAISHYQEQQQPRNIEVNGPTTDMIGEAPAMQDVFRIIGRLSRS
                     SISVLINGESGTGKELVAHALHRHSPRAKAPFIALNMAAIPKDLIESELFGHEKGAFT
                     GANTIRQGRFEQADGGTLFLDEIGDMPLDVQTRLLRVLADGQFYRVGGYAPVKVDVRI
                     IAATHQNLERRVQEGKFREDLFHRLNVIRIHLPPLRERREDIPRLARHFLQVAARELG
                     VEAKLLHPETETALTRLAWPGNVRQLENTCRWLTVMAAGQEVLTQDLPGELFEASAPD
                     SPSHLPPDSWATLLAQWADRALRSGHQNLLSEAQPELERTLLTTALRHTQGHKQEAAK
                     LLGWGRNTLTRKLKELGME"
     gene            complement(12716..13765)
                     /gene="glnL"
                     /locus_tag="OPV72_002110"
     CDS             complement(12716..13765)
                     /gene="glnL"
                     /locus_tag="OPV72_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen regulation protein NR(II)"
                     /protein_id="HCR9914408.1"
                     /translation="MASGIQPDAGQILNSLINSVLVVDDALAIHYANPAAQQLLAQSS
                     RKLFGTPLPELLSYFSLNIDLMRESLAAGQGFTDNEVTLVIDSRSHILSLTAQRLPDD
                     FILLEMAPMDNQRRLSQEQLQHAQQIAARDLVRGLAHEIKNPLGGLRGAAQLLSKALP
                     DPALTEYTKVIIEQADRLRNLVDRLLGPQHPGMHITESIHKVAERVVALVSMELPDNV
                     RLIRDYDPSLPELPHDPEQIEQVLLNIVRNALQALGPEGGEITLRTRTAFQLTLHGER
                     YRLAARIDVEDNGPGIPPHLQDTLFYPMVSGREGGTGLGLSIARNLIDQHAGKIEFTS
                     WPGHTEFSVYLPIRK"
     gene            complement(14040..15449)
                     /gene="glnA"
                     /locus_tag="OPV72_002111"
     CDS             complement(14040..15449)
                     /gene="glnA"
                     /locus_tag="OPV72_002111"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--ammonia ligase"
                     /protein_id="HCR9914409.1"
                     /translation="MSAEHVLTMLNEHEVKFVDLRFTDTKGKEQHVTIPAHQVNAEFF
                     EEGKMFDGSSIGGWKGINESDMVLMPDASTAVIDPFFADSTLIIRCDILEPGTLQGYD
                     RDPRSIAKRAEDYLRATGIADTVLFGPEPEFFLFDDIRFGASISGSHVAIDDIEGAWN
                     SSTKYEGGNKGHRPGVKGGYFPVPPVDSAQDIRSEMCLVMEQMGLVVEAHHHEVATAG
                     QNEVATRFNTMTKKADEIQIYKYVVHNVAHRFGKTATFMPKPMFGDNGSGMHCHMSLA
                     KNGTNLFSGDKYAGLSEQALYYIGGVIKHAKAINALANPTTNSYKRLVPGYEAPVMLA
                     YSARNRSASIRIPVVASPKARRIEVRFPDPAANPYLCFAALLMAGLDGIKNKIHPGEA
                     MDKNLYDLPPEEAKEIPQVAGSLEEALNALDLDREFLKAGGVFTDEAIDAYIALRREE
                     DDRVRMTPHPVEFELYYSV"
     gene            15825..17648
                     /gene="typA"
                     /locus_tag="OPV72_002112"
     CDS             15825..17648
                     /gene="typA"
                     /locus_tag="OPV72_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-dependent GTPase TypA"
                     /protein_id="HCR9914410.1"
                     /translation="MIENLRNIAIIAHVDHGKTTLVDKLLQQSGTFDARAETQERVMD
                     SNDLEKERGITILAKNTAIKWNDYRINIVDTPGHADFGGEVERVMSMVDSVLLVVDAF
                     DGPMPQTRFVTKKAFAHGLKPIVVINKVDRPGARPDWVVDQVFDLFVNLDATDEQLDF
                     PIIYASALNGIAGLDHEDMAEDMTPLYQAIVDHVPAPDVDLDGPLQMQISQLDYNNYV
                     GVIGIGRIKRGKVKPNQQVTIIDSEGKTRNAKVGKVLTHLGLERIDSDIAEAGDIIAI
                     TGLGELNISDTICDPQNVEALPALSVDEPTVSMFFCVNTSPFCGKEGKFVTSRQILDR
                     LNKELVHNVALRVEETEDADAFRVSGRGELHLSVLIENMRREGFELAVSRPKVIFREI
                     DGRKQEPYENVTLDVEEQHQGSVMQALGERKGDLKNMNPDGKGRVRLDYVIPSRGLIG
                     FRSEFMTMTSGTGLLYSTFSHYDDIRPGEVGQRQNGVLISNGQGKAVAFALFGLQDRG
                     KLFLGHGAEVYEGQIIGIHSRSNDLTVNCLTGKKLTNMRASGTDEAVILVPPIKMSLE
                     QALEFIDDDELVEVTPTSIRIRKRHLTENDRRRANRGQKEE"
     gene            complement(17703..18437)
                     /locus_tag="OPV72_002113"
     CDS             complement(17703..18437)
                     /locus_tag="OPV72_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HCR9914411.1"
                     /translation="MRYRLIAFDLDGTLLNRNKQILPESLTAIRQMQDMGCRIMLVTG
                     RSHREAYAYYQTLALTEPMICCNGSYIYQPAQQQILDPLPLTHLQTEKILARVYPLKP
                     TIRADDKIIFQADELSSRENIWQISVVHRHIKQLQNIAEFIQHELQLSCTWSWHHQLD
                     ILQKGCSKGQSLARYAQQQHIAMREVMAFGDNDNDAEMLRLAGLGVAMGNASARAKVY
                     ADSVIGRHNTPTIADFLTTLSLSQRE"
     gene            complement(18422..19300)
                     /locus_tag="OPV72_002114"
     CDS             complement(18422..19300)
                     /locus_tag="OPV72_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STM4011 family radical SAM protein"
                     /protein_id="HCR9914412.1"
                     /translation="MSIPALRDIHTLFYRGYLKSCNYHCGYCPFHKHARNDKKRDEAA
                     LWRMVDHLPLLGTPLNVMITPYGEALRLRYYMAALADISRYPHVQAVGIQTNASFSLM
                     SLLESFRAGGGDISKLRLWCSFHPSQITAERFLQQCLALSAAGITWCAGAVASMKDID
                     QFRWLRQRLPDQNYFWFNANECANTRHTVEETIAFSELDPLYVVETQQWPAQLDICTA
                     GRKSIFMNAEGDLFACHISKIKMGNLYQQRLNSPACQAKQCHCFLAYQHRLDIPLLNH
                     LDASRCFRIGRSCDIV"
     gene            complement(19297..20487)
                     /locus_tag="OPV72_002115"
                     /pseudo
     CDS             complement(19297..20487)
                     /locus_tag="OPV72_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462892.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="STM4012 family radical SAM protein"
BASE COUNT         5077 a         5150 c         5422 g         4838 t
ORIGIN      
        1 gaagaagccc atcctgacgg atgggctttt ttgcatgtgt ggtaactgta aaaatgtagg
       61 cctgataagc gcagcgccat caggcaacct gcaccgccgg atggcggctc cgccttatcc
      121 ggcctacaag gaacgtgctt tctctaacca ccgcaaaatg aaggcagaaa tctgcgatac
      181 atcattaaga tccaaaacgg gtaccgctac ggcaagtgga atatcactgg caaccgcaat
      241 aacatgctca tcaagaatta attcttcctc gctgtgccca catccctgac gaaaaagtaa
      301 gatcttcgca actgcttcgt gtttaaaccc ttcaacaagc accagatcca gttttgatgc
      361 atccatccgg ctcaccagcc atgccagatc caactcttct tgccccggcg tttccgtcat
      421 taacgcccag cgctgctgac tggcaaccag cgtctgtgcc gccccggctt tacgcagctc
      481 gtagctatct ttacccggtt tatcgacatc catatcatga tgggtatgct taatcagccc
      541 tggccgaata ccgtgcgcac aaagtgctgg gatcagtttt ttcagcagtg ttgtttttcc
      601 cgtgccgctc catgcggcaa tggcgagtag cggtatcatg gtctcttttg ccattgcgcg
      661 agttcctccg gcgtgttgac gttcacaaat gcctccttac aatcgctgaa atcaacggcg
      721 tgtccgccta cctggcgcat aaaaatcatt acccgccgct cgcctgcttg caaataagct
      781 gtcaactggg gctcaacggc acgattaatc aacgcgatcg ttggatgatc gcgttctcca
      841 tcatgaaccc aaaccacggg tgcgccatga cgatgcgctg ctaaacgatc gaccaggttg
      901 tgggggatac aaggattgtc acagggacaa aacagaaacc agtcgcctgc tacctgctga
      961 aaaacggaaa gcatacccgc cagcggaccg ggaaagtcag cgattgaatc cggaatgact
     1021 ttcaggccgc tggcctggta gatatccaga tggcgattag cactaattac gaccgtagca
     1081 agttgtggcg cgagcgcgtc ggcaacgtgt cgccagagcg gtttcccgtc cagttcaagc
     1141 agacctttat ccgcacctcc catccgccgg gctttaccgc ctgccagtac cacgccggtt
     1201 attacttcat ccagattcac cgatatcgcc tcttttattg tgggattgac cctgctaccg
     1261 tgtctgtatc aagaataagg agcacagcta tgaaatgtaa acgcttgaat gaagtcattg
     1321 aactcctcca gccagcctgg cagaaagagc ctgatcttaa tctgacgcaa tttttgcaga
     1381 aactggcgaa agagtcaggt tttgacggca aactggaaga tttaactgat gatatcctga
     1441 tctaccatct gaaaatgcgc gattccgcca aagacgccgc cattccaggg attcaaaaag
     1501 actatgaaga ggactttaaa acggcgcttt tacgcgcccg cggcgttatt aaagagtaaa
     1561 accttgtaag cggcaccacc gaaatcgcca cgaaatgata tcctgaatca ttcgtagtat
     1621 tttccggatg atgggatgaa cgacaacgct tttactttcc agacgctaca cccggaaacc
     1681 atcatggatg cgctgtttga acaggggatc agggtggatt ccgggctgac tccactaaac
     1741 agttatgaaa accgcgtcta tcagtttcag gatgaagacc gtcgacgttt tgtcgttaag
     1801 ttttatcgtc ctgaacgctg gtctgttgat caaattcggg aagaacacca attcgcgctt
     1861 gaactggtga aggatgaggt tccggttgct gctccgctcg cgtttaatgg ccagacgctg
     1921 ttagcgcatc agggctatca ttatgccatt ttccccagcg taggcggtcg tcagtttgaa
     1981 gcagacaata tcgatcagat ggaggcggta gggcgttatc ttggccgatt gcatcagacg
     2041 gggcgaaaac gtcctttcac tttccggcct gacattgggc ttgcagagta tctttttgaa
     2101 cctcgccagg tattcgaaga tgccgcactg attccctccg ggcaaaaagc ggctttcctg
     2161 aaagccactg atactctact gtctgcggtt accgaatgct ggcgcaccga tttcgccacg
     2221 ctgcgattgc acggcgattg tcatgccggc aacattctat ggcgtgatgg accgctgttt
     2281 gtcgatttag atgatgcccg taacggcccg gcgatacagg atttatggat gctgctgaac
     2341 ggcaacaaag ccgaacagcg aatgcagctt gaaaccatta ttgaagctta tgaagaagtt
     2401 agtgagttcg atacggctga aattggtctc attgaacctt tacgcgccat gcgtttagtt
     2461 tattatcttg cctggttgat tcgtcgttgg ggcgatcctg cgtttccaaa aaactttcct
     2521 tggttaacag gggaagatta ctggcagcga cagacaacga cttttattga gcagactaaa
     2581 attttgcacg aacccccttt acaattaacg ccaatgtatt aatcggagag agttgatcat
     2641 gaaaaagatt tggctggcgc tggctggtat ggttttagct tttagcgcct cggcagcaca
     2701 gatcagcgac ggtaaacagt atatcacgct ggataaaccg gtcgctggcg aaccccaggt
     2761 actggagttt ttctcattct actgcccaca ttgttatcag tttgaagaag tgcttcatgt
     2821 gtctgacaat gtgaagaaaa agctgccgaa aggcaccaag atgaccaagt accacgttga
     2881 gttcctgggg ccgttgggca aggagctcac ccaggcatgg gcggtggcga tggcgttggg
     2941 ggtagaagat aaagtcacgg tcccgctgtt tgaagccgta cagaaaaccc agacagtaca
     3001 atctgccgcg gatatccgta aagtgttcgt tgatgcgggc gtaaaaggcg aagattacga
     3061 tgcggcatgg aacagcttcg tggtgaaatc actggttgcg caacaggaga aagccgcggc
     3121 tgacctgcaa ctgcagggcg ttccggcgat gttcgtcaat ggcaaatacc agattaaccc
     3181 acaaggcatg gataccagca gcatggatgt ttttgttcag cagtatgctg ataccgtgaa
     3241 atatttggtt gataaaaaat aaaaagaacg ccggtcactg accggcgttt ttataagatg
     3301 ttttaatctc ttctatctgt atatctttct tatcccacag cgtattaagc caacgttgaa
     3361 aacggcgttt gaatgttttg tcgttcacgt aatcgccgtg cagttcttca tttatgggtt
     3421 ccagttgcac ccgaacaaca atacgcgtca gcctaccgct tagcatatcg tagaaggggt
     3481 ggcgatcgtt gtttgggtaa cacaacgtaa tattaagcag cttatcgaac tgtgagccta
     3541 aaacattaat cgccattgca ataccggctg cttttggtgg caacagatgt tgatagggtg
     3601 aatgcgtttg ctgacgtttc tcatgcgtaa atcgcgagcc ttcaacaaag ttaacgatag
     3661 tggtgggata ccgacgaaac ttctcgcaag agcggcgagt tgtttcaaca tctttgccac
     3721 gtcgatcggg gtggcggagc agatagctac gagagtagcg cttcataaac ggcatatcta
     3781 atgcccagca cgccaggccg atgaacggca cccaggccaa ttgctgttta agaaagtact
     3841 tattcattgg gatatgcttg cggaacagaa cgcaaagcac aacgatatcg gcccagctgc
     3901 ggtgattaca aatcagtaaa taccaatttt tcttgctcag cccttctaac ccttctacat
     3961 cccattgcaa gtgcggatta aggcgtaaca gcgctgcaag accagcacac cagcaataca
     4021 tcatgaaatt gcagaaaatg gagaccttgc gccagatacc gggaacaggc aaaaggagct
     4081 ttaccatgcc ggcaacgatg atcggtactg agcaaacaat agtgaccagg atggttaata
     4141 cgatactcaa tgggagcgtg atagccgcga gtattctcgt cataataaat tattcaaaag
     4201 ttagccataa acggtgtgcg aaaagggcgc aagaggctga ttctatcaga aaacgatgct
     4261 aatgatggcg ctgagtgaaa tagaaacact cgtaacaact atccacatta tgataacggc
     4321 atgaatcaga taatcagaaa atcgtgatgt taacaactca ttgaaaataa tgggtaatta
     4381 ttaagaggag aaggctatcg cgctgatttt aaagtaatgg taagaattta cacacaaagt
     4441 tatccacagg ttgttttgcg agcgatcctg aagatcgaca aaacttttcc gcaaatgcgg
     4501 cgaaaaactc aagttttcct cctgtatgtg gcatccttta accataatct gttaaacagg
     4561 cacggacatt atggttcaga tcccagaaaa cccacttatt ctcgtagatg gctcatccta
     4621 tctctatcgc gcctatcatg cgtttccgcc gttaaccaac agcgcgggag aacctacggg
     4681 cgcaatgtat ggtgtcctca acatgttgcg cagcctgatc atgcagtatc agccgacgca
     4741 tgctgcggtg gtgtttgacg ccaaaggaaa aaccttccgt gacgagctct ttgaacacta
     4801 caaatcgcat cgtcctccga tgccggatga tctgcgtgcg caaatagagc cgttacatgc
     4861 catagttaaa gccatggggt tacctctgct ggcggtctct ggcgtagaag cggatgacgt
     4921 tatcggtaca ctggcgcgag aagcggagaa ggtggggcgt ccggtattaa tcagcaccgg
     4981 cgataaagat atggcacagt tggtgacgca gaatattacg ctgatcaaca ccatgactaa
     5041 caccatcctc ggcccggatg aagtcgttaa taagtacggt gtgccgcctg agctgattat
     5101 tgactttctg gcgctgatgg gggactcctc ggataatatt ccgggcgtac caggcgtggg
     5161 tgagaagacg gcgcaagcct tgcttcaggg attgggcggc ctggatacgc tgtacgccga
     5221 gccggaaaaa attgccggtc tcactttccg cggcgccaaa acgatggccg gtaaattagc
     5281 gcagaataaa gacgtagcgt acctgtctta taagctcgcc accattaaaa cggatgttga
     5341 gctggagctg acctgcgaac agcttgaagt gcagcagccg attgcggatg aactgctggg
     5401 cctgtttaaa aaatatgagt tcaagcgctg gacggcggac gtcgaggcag gcaagtggct
     5461 acaggcaaag ggcgcgaaac cggcggccaa accgcaggaa acggtcgtta ttgatgaatc
     5521 gcccagcgaa ccggcagcgg cgctctctta tgaaaattat gtcacgattc tggatgacgt
     5581 tacgctggaa agctggattg aaaagctgaa aaaagcgcca gtttttgctt tcgacacgga
     5641 gaccgacagc ctggataata tcgccgccaa cctggtgggc ctctcgtttg ccatcgaacc
     5701 tggcgttgcc gcgtatgtac ctgtcgcgca tgattatctg gacgctccgg atcaaatctc
     5761 ccgccagcgt gctctggaac tgctgaagcc tctgctggaa gatgaaaaag tgcgcaaagt
     5821 ggggcaaaac ctcaagtacg atcgcggcgt cttgcaaaat tacggtattg agctgcgcgg
     5881 tatcgccttc gataccatgc ttgagtctta cattctgaac agcgtcgccg gacgccatga
     5941 tatggacagc ttgtccgatc gttggctgaa gcacaaaact atcacctttg aagacattgc
     6001 cggtaaaggt aaaaaccagc tcacctttaa ccagatcgca ctggaggaag cggggcgcta
     6061 tgcggcagaa gatgcggatg tcacgttaca gttgcatctc aaaatgtggc ctgagctcca
     6121 gcagcacaaa ggcccgctga atgttttcga aaacatcgaa atgccgctgg tgccggtact
     6181 gtcacgcgtt gagcgcaatg gcgtaaaaat cgatcctgcc gtcctgcaca aacattcgga
     6241 agaaatcacg ctacgtctgg cggaactgga aaagaaagcg catgacattg cgggcgaggc
     6301 gttcaacctg tcctcgacga agcagttgca gaccatcctg tttgaaaagc agggtattaa
     6361 gccgttgaag aaaacgcctg gcggcgcgcc gtcaacgtcg gaagaggtgc tggaagagct
     6421 ggcgctggac tatccgctgc cgaaagtgat tctggagtat cgtggtctgg cgaagctaaa
     6481 atccacctat accgataagc tgccgctgat gattaacccg aaaaccgggc gcgtccatac
     6541 gtcctatcat caggcggtaa cggcgacggg acgtttatcg tccaccgatc cgaacctgca
     6601 aaatattccg gtgcgcaatg aagaaggccg ccgcattcgt caggcattta ttgcgcctga
     6661 ggattatctc atcgtatctg cggactattc acagattgag ctgcgtatta tggcgcatct
     6721 ttcccgtgat aaagggctgc tcacggcgtt cgccgaaggg aaagatattc accgcgcaac
     6781 ggcggcggaa gtctttggct tgccgctgga tagcgtgacc ggggaacagc gccgaagtgc
     6841 gaaagccatt aactttggcc tgatttacgg gatgagcgcc ttcggtcttt ctcgccagct
     6901 taatattccg cgtaaagagg cgcagaagta tatggatctc tacttcgaac gctaccctgg
     6961 cgtgctggaa tatatggagc gcacccgcgc tcaggcaaaa gaacaaggct atgtggaaac
     7021 tctggagggg cgccgccttt acctgccgga tattaaatcc agcaacgcgg cgcggcgcgc
     7081 gggggcggaa cgcgcggcga tcaatgctcc catgcaagga acggctgccg atatcatcaa
     7141 gcgcgccatg attgccgtcg atgcctggct acaggccgag cagccacgcg tgcggatgat
     7201 tatgcaggta cacgatgaat tagtgttcga ggtgcataaa gacgacttag atgcggtagc
     7261 aaaacgtatc catcagttga tggaaaactg cacgcgtatt gatgtgccgt tgctggtgga
     7321 agtcggtagc ggagaaaatt gggatcaagc gcactaagca tttaaggaat aacgcgcttt
     7381 tttcgtaatt aagcaacata agcacggggg ttttgtgatg ggtattagaa ttccctatgt
     7441 aaagaatgaa aaaaaaatta cgaaaaggtc tttctgtgtt gctcaaaaaa gagtaaagtt
     7501 attcacgtag ggtacagagg taagatgttc tatctttcag accttttact tcacgtaatc
     7561 ggatttggct gaatatttta gccgccccag tcagtttatg actggggcgt tttttattgg
     7621 gcgtaagaaa agtttcgctc gcaccgtagg ccggataaga cgcgcagcgg cgccatccgg
     7681 catagcgggt gattattccc cgtcctgaat ctcttcgacc ggtgccagtt cactaaacca
     7741 gctatccagt ttctgacgta acttatccac tccctgcttt ttcagcgagg aaaacgcttc
     7801 tacctgcaca tcgccattaa aagccagcac ggcttcacgt accatattca actgcgcctt
     7861 gcgcgcgccg ctggccagtt tgtccgcttt ggtcagcaga accagaacct ggatattgct
     7921 ctctacagcc cactggatca tctgttggtc gaggtctttc aacggatggc ggatatccat
     7981 taaaacgact aagccctgta ggctttgacg tttctccaga tattccccca gcgcgcgttg
     8041 ccacttgcgt ttcatctctt ccgggacttc cgcgtagcca tagcccggca ggtcgaccaa
     8101 ccgtttgcca tctacgactt caaacaggtt aatcaattgg gtacggcccg gcgttttaga
     8161 ggtgcgcgcc aggctttttt ggttggtcaa cgtgttcagg gcgctggatt tgcctgcatt
     8221 ggaacggcca gcaaaagcca cttcaattcc gcaatcggaa ggtaaatggc gaatatcagg
     8281 cgcactcatc acaaaatgcg tctgttgata attcaggtta gtcaaagcgg tcgtctccgt
     8341 cagtcaaagc attgtggcga ttatacctga acgccagcaa aagacggatt tttcggcgcg
     8401 tcggtgctgt aagcaaaagc catacgcttt gtgagacatt gtccattgca cttatgcgac
     8461 atgacagagt cgttgtcagg ctaaaagcca gttaatatag ttaaatcatg aatttataga
     8521 aaggtaattg tctgaaaaaa agggatttgc cgtgtcggta tcttgtgagt ttaccccaaa
     8581 agagtaaagt aatgcacata gcgaggacgc taacaggatc aacgactcag gatgagggtc
     8641 aggagcgcca ggaggcgaag acacaggatt gtcaggaaga caaacgtccg gagacgttag
     8701 taaaaggaaa tggaaacaac atggaatgtt ccaggctaag ggaaaaacag ggcgtgttga
     8761 tagccaacag ggatggtgga acccgttaag ggtcgtgagt caagaaaaaa ggcggcagat
     8821 tactctgtcg ccttttttct ttgcttgctt tctgctagat tccgcctcaa ttctatactg
     8881 aataaaacgg cttaaagatc tgacatcatg aaaaaaccaa cctctgcacc gcgcagtaaa
     8941 gcctttggca aacagcgtcg taaaacgcgt gaagagttaa accaggaggc gcgcgaccgt
     9001 aaacgcctga aaaaacatcg cggccatgcg ccgggaagtc gcgcggcggg cggcaattcc
     9061 gcttcgggcg gcggcaatca gaatcaacaa aaagatccac gtattggcag taaaacacct
     9121 gttccattgg gcgtgactga aaaagtgacc caacagcata aaccgaaaag tgagaaacct
     9181 atgctttcac cgcaggcgga gttggattta ctggaaacgg atgagcgcct ggatgcgctg
     9241 ttagaacgtc tggaagcggg cgaaaccctg agtgcggaag atcaagcctg ggtagatgcc
     9301 aaactggatc gtattgatga actgatgcag aagcttggtc tgtcttacga tgacgacgaa
     9361 gaagacgacg aagaggacga gaagcaggaa gatatgatgc gcctgctaag aggcggcaac
     9421 taacgggttt acaccgtggg cttgcccgtc ctgcttataa cccttccggt tatatgttat
     9481 ctggtgtggt tattcgttaa actacagcga ttgtcgcggc gacagaaatg gctgcgcagc
     9541 cggcttgccg cccgtcatgg cgtgaagccg gtacgccgta cccgccagag acgccatcgg
     9601 aaggagtgag catgtctgaa cagcaaatag actgggatct ggccctgatc cagaaatata
     9661 actattccgg gccacgatat acctcgtacc caaccgcgct ggagttttct gaagacttcg
     9721 aggacgccgc attcttgcag gctgtggcgc gttatcctga acgtccgctc tcgctgtatg
     9781 tgcatatccc gttttgtcac aagttgtgtt atttctgcgg ctgcaacaag attgtcaccc
     9841 gccaacagca taaagctgac cagtatcttg acgcgcttga gcaggaaatt cgccatcgcg
     9901 cgccgctgtt tgcagaccgt catgtcagcc agcttcactg gggcggcggt acgcctactt
     9961 acctgaataa agcgcaaatc agccgcttaa tgacgctgtt gcgtgaaaat ttccacttta
    10021 ataccgacgc ggaaatctcg atcgaagtcg atccccgtga aattgagctg gatgtgctcg
    10081 atcatttacg tgcggaaggt tttaaccgcc tgagtatggg cgtgcaggac tttaataaag
    10141 aggtgcagcg cctggttaac cgcgagcagg atgaagaatt catctttgcg ttgcttaatc
    10201 acgcccgcga tatcggcttt acctcgacca atatcgactt gatctacggt ctaccgaaac
    10261 agacgccgga aagcttcgct ttcacgctga agcgtgtgac ggaactgaac cccgatcgtt
    10321 tgagcgtctt taactatgcg catctgccaa cgctttttgc cgcccagcgt aaaattaaag
    10381 atgccgattt acccagcgcg cagcagaaac tggatatttt gcaggagacg atcgtatcgc
    10441 ttactcaggc cggttatcag tttatcggga tggaccattt tgcccgtccg gatgacgaac
    10501 tggccgtcgc gcagcgcgaa ggcgtgctgc accgtaattt tcagggctat acgacccagg
    10561 gcgataccga tctgctgggg atgggcgttt ctgctatcag catgattggc gatggctaca
    10621 tgcagaacca gaaagagctg aagcgttatt accagcaagt ggatgagcgg ggcaatgcgc
    10681 tatggcgtgg tattacgctg acccgtgatg attgcattcg tcgcgatgtt atcaaggcgc
    10741 tgatttgtaa cttccgcctg gattttaacg ctgtcgaaca gcagtggggt ttgcatttcg
    10801 ctgaatattt tgccgaagat ttgcagttac tgtcgccgct ggcgaaagat gggctggtgg
    10861 atattagcga gaagggaatt caggtgacgg cgaaaggtcg tttgctgatc cgcaatatct
    10921 gcatgtgctt tgacgcgtat ctgcgccaga aagcgcggat gcagcagttc tcgcgcgtca
    10981 tttagccggg ttgcccggtg gcgctgcgct taccgggcct acacgttgcg acaacctgta
    11041 ggccggataa gcattagcgc catccggcac attgtcagct gaacagtccc accagcgcgg
    11101 cacacaacac ggcggctagc gcagtttgtg gcgtgtggct gtcgaccgct ccactcgata
    11161 ccagattaat aatagattct aacataatga atccccccgt ttgccgggca tgatcatact
    11221 gaactcatcg gaacagtaaa gcgcaaaata gcagcgtttt gcgctcaatt attaatcttt
    11281 acactcgcgg ataatgttta ctccattccc agctctttca acttccgcgt tagggtgttt
    11341 cgaccccaac cgagcagctt ggcggcttcc tgtttatgac cctgcgtatg gcgtaacgcc
    11401 gtggtcagta gcgttctttc cagttctggc tgcgcttcag aaagcaggtt ttgatgaccg
    11461 gatcgcaagg cgcgatccgc ccattgcgcc agtaatgtag cccagctatc cggcggcagg
    11521 tgggacgggc tatccggcgc cgaggcttca aacagttcgc ccggtaaatc ctgggtcaat
    11581 acctcctgtc cggcggccat gacggtgagc cagcggcagg tattttctaa ctgacgcacg
    11641 ttaccaggcc atgccaggcg cgttaacgcc gtttcggttt ccggatgtaa taatttggct
    11701 tccacgccta attcacgggc ggcgacctgc aaaaaatggc gcgccaggcg cggaatatcc
    11761 tcacggcgct cgcgcaacgg cgggagatgg atacgaatca cgttcaggcg gtggaacagg
    11821 tcttcacgga atttcccttc ctgaacgcgt cgttcgaggt tctggtgggt ggcggcaata
    11881 atgcgcacat ccacttttac cggcgcgtac ccgcccacac ggtagaactg tccgtcagcc
    11941 agcacgcgta acagacgagt ctggacatcc agcggcatat cgccaatttc gtccagaaac
    12001 agcgtaccgc cgtcagcctg ctcgaaacgg ccctgccgga tggtattcgc cccggtaaaa
    12061 gcgcctttct catggccaaa caattcggat tcaatcaaat ctttcgggat ggccgccata
    12121 ttgagcgcga taaacggcgc tttggcgcgt gggctatggc gatgtagcgc atgggcgacc
    12181 agttctttac cggttcctga ttcgccgtta atcagcacgc taatcgaaga acgcgacagc
    12241 cgaccaataa tgcgaaacac atcctgcatg gcgggcgctt cgcctatcat gtctgttgtc
    12301 gggccgttaa cctcgatatt acgcggctgc tgctgctcct gatagtggct aatcgctcgc
    12361 tcgaccagag cgacggcttc atcaatatca aacggtttag gcagataatc aaacgccccc
    12421 tgctgataag cgctcacggc ggcatctaaa tcggaatgcg cggtcataat gatgaccgga
    12481 agcatcggat gacgttgttt aatctgcttt aatagcgcca gcccgtccat tcctggcatt
    12541 cggatatccg acagcaagac gtccggcgtt ttactggcca gcgcagccag tacttcatta
    12601 ccattctcaa aggtgataca ggtcaaccct gccccggcga gagcacgttc aagcacccaa
    12661 cggatggaac tatcatcatc gacgacccag actattcctc gttgcataaa cacctctatt
    12721 tccgaatcgg caggtaaacc gaaaactcgg tatgccccgg ccaactggta aattcaattt
    12781 tgccggcgtg ttgatcgata agattgcggg cgatagataa cccaagcccg gtgccgcctt
    12841 cgcgaccgct gaccatcggg tagaacagcg tatcctgtaa atggggagga atgcccggcc
    12901 cattgtcttc aacgtctata cgcgccgcca ggcgatagcg ttcgccatgc agcgttaact
    12961 ggaaggcggt acgggtacgc agcgtaattt cgccgccttc cggccccagc gcctgcaagg
    13021 cattgcggac aatattcagc agtacttgct caatttgttc cgggtcgtgc ggcagttctg
    13081 gcagactggg gtcgtaatcg cggataagcc ggacattatc cggcagttcc atcgacacca
    13141 gcgccaccac gcgctccgcg actttatgta tgctctcggt aatgtgcatt cccgggtgct
    13201 gcggccccag caaacgatcg acaaggttgc gtagcctgtc ggcctgttca atgatgactt
    13261 tggtatattc cgttagcgcc gggtcgggca gcgccttgct gagtagctgc gccgcgccgc
    13321 gcaggccgcc gagcggattt ttgatttcgt gcgccagacc gcgcaccaga tcgcgggcgg
    13381 cgatttgctg cgcgtgctgc aactgctcct gactcagacg acgctggtta tccatcggcg
    13441 ccatttcgag cagtataaaa tcgtcgggca gacgttgggc ggtcaaagag agaatatgcg
    13501 agcgactatc aatcaccagc gtcacttcgt tatcggtaaa gccttgtcct gccgctaaac
    13561 tttcgcgcat caggtcaatg tttaacgaaa aatagctcaa cagttcaggt aacggcgtcc
    13621 cgaacagttt gcgtgagctt tgcgcgagca actgctgcgc ggcagggttg gcgtaatgga
    13681 ttgccagcgc gtcgtcgacc accagcacgc tgttgattaa cgaattgagg atctgcccag
    13741 catcgggctg tatgccgctt gccattcagc agtctcctgg aaaaggttgc accattttag
    13801 tgcattatag ctttttacca ctaaaaagcg cgtgagatca gattgttggt ggagaaaaaa
    13861 gcccatcctg ggatgggctg aaagtttcca cggcaactca aaaactcctg acgcctttca
    13921 cgctgctgct gcgttggctg ccttcgctta ccccggtcac atcgctatct atgctcccgg
    13981 ggatgtgctc agttgccgcc ttgcagcaac gcgaaattcg tcggattttt aatatacgat
    14041 taaacgctgt agtacagctc aaactctacc gggtgcgggg tcatacgcac gcggtcatct
    14101 tcttcgcgac gcagcgcaat atacgcatcg atcgcttcat ccgtgaacac gccgcctgct
    14161 ttcaggaact cgcggtccag gtccagcgcg ttcagcgctt cttccagaga acctgctacc
    14221 tgtgggatct ctttcgcttc ttccggcggc aggtcataca ggtttttgtc catggcttcg
    14281 cccgggtgaa tcttattctt aatcccgtcc agaccggcca tcagcagggc ggcaaagcac
    14341 agatacgggt tagccgccgg gtccgggaag cgaacttcga tacggcgcgc tttcggagac
    14401 gccaccaccg gaatacggat ggaggcggaa cggttacggg cggagtaggc cagcatcacc
    14461 ggcgcttcgt aacccgggac cagacgcttg taggagttgg tggtcgggtt cgccagggcg
    14521 ttgatggctt tggcgtgttt gatgacgccg ccgatgtagt acagcgcctg ctcagacaga
    14581 ccggcatatt tgtcgccaga gaacaggttg gtgccgttct tcgccagcga catgtggcag
    14641 tgcataccgg aaccgttatc gccgaacatc ggttttggca taaaggtcgc ggtcttaccg
    14701 aagcggtgag ccacgttatg cacgacatat ttgtaaatct gaatttcgtc ggcttttttg
    14761 gtcatggtgt taaagcgggt cgccacttcg ttctgacctg cggtcgctac ttcgtggtgg
    14821 tgcgcttcaa caaccaggcc catctgctcc atgaccagac acatttcaga acggatatcc
    14881 tgcgcggagt caactggcgg aaccgggaaa taaccgcctt tcacgcccgg gcgatggcct
    14941 ttgttgccgc cttcgtattt ggtagaggag ttccaggcgc cttcaatatc gtcaatcgcc
    15001 acatgtgagc cggagataga tgcgccgaag cggatgtcgt cgaacaggaa gaattcaggt
    15061 tccggcccaa acaggacggt atcggcgata ccggtcgcgc gcaggtagtc ttccgcacgt
    15121 tttgcgatgg aacgtgggtc acggtcataa ccttgcagag tgccaggctc caggatgtcg
    15181 caacggataa tcagggtaga gtccgcgaag aacgggtcga taaccgcagt ggacgcatcg
    15241 ggcatcagca ccatgtcgga ttcgttaatg cctttccagc cgccgataga ggagccgtca
    15301 aacattttgc cttcttcaaa gaattcggca tttacctgat gagcaggaat cgtgacgtgc
    15361 tgttctttgc ctttggtatc ggtgaagcgc agatcgacaa acttcacttc gtgttcgttc
    15421 agcatcgtca aaacgtgttc agcggacata cttgtactct cccggattgg tcatggtcgg
    15481 tcgtcgtggt aacgagatct tcaattctgc tggccgtgtc gccgtaaaaa tataaagcga
    15541 aatctgtgcc aactttcaca ttgcccccaa aaggcgttat catgcgcacc atcgtgcaaa
    15601 agggctgcac cacggtgact atgttgcacc aaaatagtgc ttcaatgtga acattaagca
    15661 ccacattggt gcaatagaac gcaagccacc cttttaacgc tccgtgaaag cgatcacaaa
    15721 gagactctgc aatacttgtt tgcggaggat gtttgtgatc ctgttttgta gtgcgattaa
    15781 tccgtgtaca ataacgcgct atttctaatg cctgaggcaa agttgtgatc gaaaatttgc
    15841 gtaacatcgc catcatcgcg cacgttgacc atggtaaaac taccctggtt gataagctgc
    15901 tccagcaatc cggtacgttc gacgcgcgtg ccgaaactca agagcgagtg atggactcca
    15961 acgatttgga gaaagagcgt ggtattacta tcctcgctaa aaacaccgct attaaatgga
    16021 atgattatcg tatcaacatc gttgatactc ccgggcacgc tgacttcggt ggtgaagtag
    16081 agcgcgtcat gtccatggtt gactctgtgc tgctggtggt tgacgcattt gacggcccga
    16141 tgccgcaaac gcgcttcgtg accaaaaaag cctttgctca tggcctgaaa cccattgtgg
    16201 ttatcaacaa ggttgaccgt cctggcgcgc gccctgactg ggttgtcgac caggtattcg
    16261 acctgtttgt taacctcgac gcgaccgacg aacagctgga cttcccgatc atctacgctt
    16321 cggcgctgaa cggtatcgcg ggtctggacc acgaagatat ggcggaagac atgaccccgc
    16381 tgtatcaggc gatcgttgat catgttccgg cgccggacgt tgacctcgat ggtccgttgc
    16441 agatgcagat ctcccagctg gactacaaca actacgttgg cgttatcggc attggccgta
    16501 tcaaacgcgg caaagtgaag ccgaaccagc aggtcactat catcgatagt gaagggaaaa
    16561 cccgtaacgc gaaagtaggt aaggtgctga cgcatctggg tctggagcgt atcgacagcg
    16621 atatcgccga agcgggcgat atcattgcga tcaccggtct gggcgagctg aacatttccg
    16681 acaccatctg cgacccgcag aacgttgaag cgctgccggc gctgtccgtt gatgagccga
    16741 ccgtgtctat gttcttctgc gttaacacct cgccgttctg cggtaaagaa ggtaagtttg
    16801 tgacttctcg tcagattctt gaccgtctga acaaagagct ggtgcataac gtggcgctgc
    16861 gcgttgaaga aaccgaagat gcggatgcgt tccgtgtatc cggtcgtggc gaactgcacc
    16921 tgtccgtgct gattgaaaac atgcgtcgtg aaggtttcga actggcggtt tcccgtccga
    16981 aagttatctt ccgtgaaatc gacggtcgta aacaagagcc gtacgaaaac gtgacgctgg
    17041 acgtcgaaga gcagcaccag gggtctgtca tgcaggcgct gggcgagcgt aaaggcgatc
    17101 tgaaaaacat gaatccggac ggtaaaggcc gcgtacgtct cgactacgtg atcccaagcc
    17161 gcgggctgat tggtttccgt tcagaattca tgaccatgac ttccggtacg ggtctgctgt
    17221 actccacctt cagccattac gacgatattc gtccgggtga agtgggccag cgtcagaacg
    17281 gcgtactgat ctccaacggt cagggtaaag cggtggcgtt tgcgctgttc ggtttgcagg
    17341 atcgcggtaa gctgttcctg ggtcacggcg cggaagttta cgaaggccag attattggta
    17401 ttcacagtcg ctccaacgac ctgacggtaa actgcctgac cggtaagaaa ctgaccaaca
    17461 tgcgtgcgtc cggtacggat gaagcggtga ttctggttcc gccaattaaa atgagtcttg
    17521 agcaagcgct ggagttcatt gatgacgacg aactggtaga agtcactcca acctctatcc
    17581 gtatccgtaa acgtcacctg acggaaaacg atcgccgccg tgcgaaccgt ggtcagaaag
    17641 aagagtaatt aacgttctta cggataaaaa ccctgccgaa atgaaaactc ggcggggttt
    17701 ttttattcac gttgagaaag ggataaggtt gtcaaaaaat cagcaatcgt tggcgtatta
    17761 tgccgaccaa tgacgctatc cgcatacacc tttgcccgag cgctggcatt ccccatcgcg
    17821 acacccaatc cggctaaacg tagcatttcc gcatcgttat cattatcgcc aaacgccatc
    17881 acttcgcgca ttgcgatatg ctgttgctgt gcatatctgg cgaggctttg tcctttgcta
    17941 caccccttct ggagaatatc cagttgatga tgccaggacc aggtacagct tagctgtaat
    18001 tcatgctgta taaactcagc aatattttgt agttgtttta tgtgccgatg aacgacgctg
    18061 atttgccaaa tattctccct actgcttagc tcatcagcct gaaagattat tttatcatca
    18121 gcacgaattg tcggtttaag cggatatacc cgcgccagta ttttttccgt ttgtaagtgc
    18181 gtcagcggca gcggatcaag gatctgctgt tgagccggtt gataaatata acttccgtta
    18241 caacagatca tcggttcggt gagcgccagc gtttgataat acgcataggc ttcacgatga
    18301 gagcgaccgg tgacaagcat tattcggcag cccatgtcct gcatctgacg gatagcggtt
    18361 agcgactctg gcagaatttg tttattacgg tttagcagcg ttccatcaag atcaaaagcg
    18421 attaaacgat atcgcatgag cgcccgatcc taaaacagcg tgaggcatcc aggtgattca
    18481 gcaatggaat atcgagacgg tgctgataag cgagaaaaca gtggcattgt tttgcctggc
    18541 aggcaggaga attgagccgt tgctgatata aattacccat tttaattttg ctgatatgac
    18601 aagcaaaaag atcgccttct gcgttcataa aaatactttt tcttcctgcg gtacagatat
    18661 ccagctgcgc tggccactgc tgcgtttcaa ccacatacag cggatcgagt tcgctgaagg
    18721 cgatggtttc ctcaacggta tgccgggtat tggcacactc gttggcgtta aaccaaaaat
    18781 aattctggtc aggcaaccgc tggcgtagcc aacgaaactg gtcgatatct ttcatactgg
    18841 cgacagcccc cgcgcaccag gttattccgg cggcagagag cgctaaacac tgctggagaa
    18901 agcgttcagc ggtaatttgt gagggatgaa aagaacacca taaccgaagc tttgagatat
    18961 ctccgccgcc agcacgaaat gactccagca atgacattaa cgaaaaagag gcgttagttt
    19021 gtatgccgac cgcctgaaca tgaggatagc ggctaatgtc tgccagcgcc gccatgtaat
    19081 aacgcaagcg tagcgcctcg ccataaggcg taatcatcac attcaacggc gtacctaaaa
    19141 gaggcaaatg gtcaaccatg cgccatagcg cggcttcgtc gcgtttttta tcgttgcggg
    19201 cgtgtttatg gaacgggcaa tagccgcaat gataattaca cgacttaaga tagccgcgat
    19261 aaaacagcgt atgaatatcg cgcagggcgg ggatgctcat ctctgccgat tctcccgtag
    19321 catcacctca ggcgaaacga acacaggagc aaggcaatcg gataatgcca taccggtctc
    19381 cgttagccgg aggcgactgc cattctgata acagtagccc tgccgtataa agcgttccag
    19441 gtcggggaaa tcccttagcg catcgctggt aaaatattgc tgataatcgc taagagaaag
    19501 tccttgccag aaaaatagat ttttaatgat aaagcggcgt ttcatttcat caggggggag
    19561 cagataaccg tgattaatga cggttttgtc cgggctgtcg ataaacgcct gaatgatttt
    19621 tcgtgatgtt tgcaggttcg acggccacgg tgaacagtaa tgcagattgc caagataact
    19681 tctgccgccc gcgccgagcg ccagtgagtt ttcaaatccg cagctttccg ccgcggcgga
    19741 tggcgctgga ttaaggacga aacggcgcat ggacgtttgg gtgtagcccg cgttgcgtaa
    19801 aagatcgcgg gctaaaacgt agtagctatg catattttcc tggcgaggca tattataaag
    19861 cggataaaga aacagctctt ccggttgata aacgagcgcc tgatgtaacg attccgtcag
    19921 gcttgcgtga gtctggccgg gaatgccgta aataatatca atattgagtg atggaaaatg
    19981 acctgccttt agccattcca acgcctggtg cgcgctggcg gtattgtggc ggcgatgcag
    20041 cgtatgtaac tcgctatcat gaaaactttg tacgccaata ctgacgcgat taacggaaaa
    20101 ggcgtttaat agcgctactt tttctgccgt ggtatccgta ggggaagttt caattgtttt
    20161 ataaatattc cagtcaacat tgagcacatc aaagacggaa aaaaataact tttctaattg
    20221 cgcaatgttt aatagcagag gtgtgccgcc gcctacggtg aagcttgccc agtggacggg
    20281 cgccagcgcc atttgtcggc cctaggtaat aatcgcgtcg atatagctat caatgaacgt
    20341 attatctgcg ccagtgcagg taaataaatt acagaacccg cagcgacttt gacaaaacgg
    20401 catatgaaca tacagatgtg tgtcgtgctc gtaaatgcgc ggttttactt tgctaaagct
    20461 gacgttctcc agctcccgat aagccgt
//
LOCUS       DAJVBX010000068        20325 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.068, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000068 DAJVBX010000000
VERSION     DAJVBX010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 20325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20325
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.068"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..1451
                     /locus_tag="OPV72_002116"
     CDS             <1..1451
                     /locus_tag="OPV72_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sigma-54-dependent transcriptional regulator"
                     /protein_id="HCR9914413.1"
                     /translation="QDYFSPLGSQFRLLDSSPASITEALEEARSLYLAFRSQLLERHH
                     LQLILDQFDKAVITLDDTGALLHYNKYASQLFKINASGEIYDASFLKQVLHQERHTLR
                     EGKTVSAKVVDTPQGAMVVNLYPVFAARQLSRVVLTMQTVSSLQGAEHHVRRQELSRR
                     GLSARYHFDDLLTENPEMLRRLAIIKNYAGTDATILINGESGTGKEVLAQSIHNASQR
                     VNGLFVAINCGAMATQILESELFGYVAGAFTGASPKGKIGLFELAHHGTIFLDEISEL
                     DKPLQTRLLRVLQERQIMRLGSDQMIPVDIRVIAATNQTLTKLIADGTFREDLYYRLN
                     VLKVTTIPLRKRPEDIKAIGLSLLTSFSQHYKRPALTLTPALWQELQRFAWPGNVRQL
                     SNIIERLVLSIDHSPATLDEGRLLLDDLEEGSRREPSTCHDCQMLAGDYKTIRLRILR
                     KLLEAERDNKSLVAKRLNVDRTSLTRWIRESA"
     gene            1544..2017
                     /locus_tag="OPV72_002117"
     CDS             1544..2017
                     /locus_tag="OPV72_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon-containing protein"
                     /protein_id="HCR9914414.1"
                     /translation="MNKVAQYYRELVASLSERLRNGERDIDALVEQARQRVMQTGELT
                     RTEVDELTRAVRRDLEEFAMSYEESQEDSVFLRVIKESLWQELADITDKTQLEWREVF
                     QDLNHHGVYHSGEVVGLGNLVCEKCHYHLAVYTPDVLPLCPKCGHDQFQRRPFEP"
     gene            complement(2056..2349)
                     /locus_tag="OPV72_002118"
     CDS             complement(2056..2349)
                     /locus_tag="OPV72_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001785127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914415.1"
                     /translation="MLRPCIIHDPDSDAGIHMLSWHGSPLIRFYTEAWCPTCAEFVYA
                     GFSNDDEGAAQFLSSLAEWNQPGVGLNEAFTALTPLFSLFADGYYRLEAQLHS"
     gene            complement(2468..3403)
                     /gene="rihA"
                     /locus_tag="OPV72_002119"
     CDS             complement(2468..3403)
                     /gene="rihA"
                     /locus_tag="OPV72_002119"
                     /EC_number="3.2.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-specific ribonucleoside hydrolase
                     RihA"
                     /protein_id="HCR9914416.1"
                     /translation="MALPIIIDCDPGHDDAIALVLALASPELEVKAITSSAGNQTPEK
                     TLRNVLRMLTLLKRPDIPVAGGAVKPLMRELIIADNVHGESGLDGPALPEPSFAPQSG
                     TAVELMAKTLRESAQPVTIVSTGPQTNVALLLNSHPELHTKIARIVIMGGAMALGNWT
                     PAAEFNIYVDPEAAEIVFQSGIPVVMAGLDVTHKAQIHAADIERFRDIGNPISTIVAE
                     LLDFFFEYHKDEKWGFVGAPLHDPCTIAWLLKPEIFTTVERWVGVETQGKYTQGMTVV
                     DYYFLTGNKPNATVMVDVDRQGFVDLLAERLQYYA"
     gene            complement(3520..4245)
                     /gene="gltL"
                     /locus_tag="OPV72_002120"
     CDS             complement(3520..4245)
                     /gene="gltL"
                     /locus_tag="OPV72_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020245804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate ABC transporter ATP binding
                     protein GltL"
                     /protein_id="HCR9914417.1"
                     /translation="MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLI
                     KTVNGLEPVQKGEITVNGIIVNDKKTDLAKLRSRVGMVFQHFELFPHLSIIENLTLAQ
                     VKVLKRDKAAARDKGLKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLF
                     DEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKIVEDS
                     PKEEFFANPSSDRAKDFLAKILH"
     gene            complement(4245..4919)
                     /gene="gltK"
                     /locus_tag="OPV72_002121"
     CDS             complement(4245..4919)
                     /gene="gltK"
                     /locus_tag="OPV72_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate ABC transporter permease
                     GltK"
                     /protein_id="HCR9914418.1"
                     /translation="MYEFDWSSIIPSLPYLLAGLVITLKITVTAVVVGIVWGTILAVM
                     RLSSFAPIAWFAKAYVNVFRSIPLVMVLLWFYLIVPGFLQNVLGLSPKTDIRLISAMV
                     AFSMFEAAYYSEIIRAGIQSISRGQSSAALALGMTHWQSMKLIILPQAFRAMVPLLLT
                     QGIVLFQDTSLVYVLSLADFFRTASTIGERDGTQVEMILFAGAVYFVISLSASLLVSY
                     LKKRTV"
     gene            complement(4919..5659)
                     /gene="gltJ"
                     /locus_tag="OPV72_002122"
     CDS             complement(4919..5659)
                     /gene="gltJ"
                     /locus_tag="OPV72_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate ABC transporter permease
                     GltJ"
                     /protein_id="HCR9914419.1"
                     /translation="MSIDWNWGIFLQEAPFGNTTYLGWLWSGFQVTVALSITAWIIAF
                     LVGSIFGILRTVPNRFLSGLGTLYVELFRNVPLIVQFFTWYLVVPELLPEDLGMWFKA
                     ELDPNIQFFLSSMICLGLFTAARVCEQVRAAIQSLPRGQKNAALAMGLTLPQAYRYVL
                     LPNAYRVIVPPMTSEMMNLVKNSAIASTIGLVDMAAQAGKLLDYSAHAWESFTAITLA
                     YVLINAVIMLVMSLVERKVRLPGNVGSK"
     gene            complement(5819..6727)
                     /locus_tag="OPV72_002123"
     CDS             complement(5819..6727)
                     /locus_tag="OPV72_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HCR9914420.1"
                     /translation="MQLRKLTTAMLVMGLSAGLAHAEDGAPAAGSTLDKIAKNGVIVV
                     GHRESSVPFSYYDNQQKVVGYSQDYSNAIVEVVKKKLNKPDLQVKLIPITSQNRIPLL
                     QNGTFDFECGSTTNNLERQKQAAFSDTIFVVGTRLLTKKGGDIKDFPDLKGKAVVVTS
                     GTTSEILLHKLNEEQKMGMRIISAKDHGDSFRTLESGRAVAFMMDDALLAGERAKAKK
                     PDNWEIVGKPQSQEAYGCMLRKNDPEFKKLMDDTIAQAQTSGEAEKWFDKWFKNPIPP
                     KNLNMNFELSDEMKALFKAPNDKALN"
     gene            complement(7145..8683)
                     /gene="lnt"
                     /locus_tag="OPV72_002124"
     CDS             complement(7145..8683)
                     /gene="lnt"
                     /locus_tag="OPV72_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="apolipoprotein N-acyltransferase"
                     /protein_id="HCR9914421.1"
                     /translation="MAFASLIERQRIRLLLALLFGACGTLAFSPYDVWPAAIVSLIGL
                     QALTFNRRPLQSAAIGYCWGLGLFGSGINWVYVSIAQFGGMPGPVNVFLVVLLAAYLS
                     LYTGLFAGILSRLWPKTNWLRVAIAAPAIWQITEFLRGWVLTGFPWLQFGYSQVDGPL
                     KGLAPVMGVEAINFLLMMVSGLLALALATRNWRPLAVAVILFALPFPLRYIQWFTLEP
                     TKATQVSLVQGDIPQSLKWDENQLLNTLNIYLNETRPELGKSQIIIWPESAIPDLEIN
                     QQPFLRSLDEMLREKNSTLITGIVDARLNKQNRYDTYNTIITLGKDNPYSYDSPNRYN
                     KNHLVPFGEFVPLESILRPLAPFFDLPMSSFSRGPYIQPQLHAHDYKLTAAICYEIIL
                     GEQVRDNFRPDTDYLLTISNDAWFGKSIGPWQHFQMARMRSLELARPLLRSTNNGITA
                     VIGPQGEIQAMIPQFTRQVLTTKVTPTTGLTPYARTGDWTVWLITVLFGFGALVMSLR
                     QRRK"
     gene            complement(8703..9581)
                     /gene="corC"
                     /locus_tag="OPV72_002125"
     CDS             complement(8703..9581)
                     /gene="corC"
                     /locus_tag="OPV72_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459659.1"
                     /note="CorC(YbeX) belongs to the Cyclin M Mg2+ Exporter
                     (CNNM) family, and was characterized as belonging to a set
                     of three proteins, at least one of which must be present
                     for CorA to function; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CNNM family magnesium/cobalt transport protein
                     CorC"
                     /protein_id="HCR9914422.1"
                     /translation="MSDDNSHSSDTVNSKKGFFSLLLSQLFHGEPKNRDELLALIRDS
                     GQNELIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSR
                     FPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRTAVVVPESKRVDRMLKEFRS
                     QRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTIRALA
                     SIEDFNDAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQ
                     VHVRIPDDSPQPKLDE"
     gene            complement(9739..10212)
                     /gene="ybeY"
                     /locus_tag="OPV72_002126"
     CDS             complement(9739..10212)
                     /gene="ybeY"
                     /locus_tag="OPV72_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HCR9914423.1"
                     /translation="MSQVILDLQLACENHAGLPDEAQFQRWLDGVIPQFQEEAEVTIR
                     LVDEAESHDLNLTYRGKDKPTNVLSFPFEAPPGIEMPLLGDLIICRQVVEQEAQEQSK
                     PLEAHWAHMVVHGSLHLLGYDHIDDDEAEEMESLETEIMLAMGYEDPYIAEKIAE"
     gene            complement(10209..11255)
                     /locus_tag="OPV72_002127"
     CDS             complement(10209..11255)
                     /locus_tag="OPV72_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005225825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HCR9914424.1"
                     /translation="MNIDTREITLEPADNARLLSLCGPFDDNIKQLERRLGIEINRRD
                     NHFKLTGRPICVTAATDILRSLYVDTAPMRGQTQDIEPEQIHLAIKEARVLEQSAESV
                     PDYGKAINIKTKRGVIKPRTPNQAQYIANILDHDITFGVGPAGTGKTYLAVAAAVDAL
                     ERQEIRRILLTRPAVEAGEKLGFLPGDLSQKVDPYLRPLYDALFEMLGFEKVEKLIER
                     NVIEVAPLAYMRGRTLNDAFIILDESQNTTIEQMKMFLTRIGFNSKAVITGDVTQIDL
                     PRNTKSGLRHAIEVLAEVDEISFNFFHSEDVVRHPVVARIVNAYEAWEEAEQKRKAAL
                     AAERKREAQEQEQK"
     gene            complement(11460..12884)
                     /gene="miaB"
                     /locus_tag="OPV72_002128"
     CDS             complement(11460..12884)
                     /gene="miaB"
                     /locus_tag="OPV72_002128"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HCR9914425.1"
                     /translation="MTKKLHIKTWGCQMNEYDSSKMADLLDATHGYQLTDVAEEADVL
                     LLNTCSIREKAQEKVFHQLGRWRLLKEKNPDLIIGVGGCVASQEGEHIRQRAHYVDII
                     FGPQTLHRLPEMINSVRGDRSPVVDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCNKY
                     CTYCVVPYTRGEEVSRPSDDILFEIAQLAAQGVREVNLLGQNVNAWRGENYDGTTGTF
                     ADLLRLVAAIDGIDRIRFTTSHPIEFTDDIIEVYRDTPELVSFLHLPVQSGSDRVLNL
                     MGRTHTALEYKAIIRKLRAARPDIQISSDFIVGFPGETTDDFEKTMKLIADVNFDMSY
                     SFIFSARPGTPAADMVDDVPEEEKKQRLYILQERINQQAMAWSRRMLGTTQRILVEGT
                     SRKNIMELSGRTENNRVVNFEGTPEMIGKFVDVEITDVYPNSLRGKVVRTEDEMGLRV
                     AETPESVIARTRKENELGVGFYQP"
     gene            13028..14203
                     /gene="ubiF"
                     /locus_tag="OPV72_002129"
     CDS             13028..14203
                     /gene="ubiF"
                     /locus_tag="OPV72_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol
                     hydroxylase"
                     /protein_id="HCR9914426.1"
                     /translation="MTNQPTEIAIVGGGMVGGALALGLAQQGFTVMVIEHAAPAPFVA
                     DSQPDVRISAISAASVALLKGLGVWEAVQGMRSHPYRRLETWEWENAHVVFDAAELKL
                     PLLGYMVENNVLQQALWQALEAHPGVTLRVPASLAALHRRHDGYALELADGEWVTPKL
                     VIGADGANSQVRQMAGIGIHAWQYAQSCMLITVKCENAPGDSTWQQFTPTGPRAFLPL
                     FDDWASLVWYDAPARIRQLQSLSMTQLQVEINQHFPARLGAVMPVAAGAFPLTRRHAL
                     QYAQPGLALVGDAAHTIHPLAGQGVNLGYRDVDALIDVLASARSYGESWASHSVLKRY
                     QTRRMADNFMMQSGMDLFYAGFSNELPPLRILRNMGLMAAQRAGVLKRQALKYALGL"
     gene            complement(14336..14410)
                     /locus_tag="OPV72_002130"
     tRNA            complement(14336..14410)
                     /locus_tag="OPV72_002130"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14376..14378),aa:Gln,seq:ctg)
     gene            complement(14457..14533)
                     /locus_tag="OPV72_002131"
     tRNA            complement(14457..14533)
                     /locus_tag="OPV72_002131"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14497..14499),aa:Met,seq:cat)
     gene            complement(14549..14623)
                     /locus_tag="OPV72_002132"
     tRNA            complement(14549..14623)
                     /locus_tag="OPV72_002132"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14589..14591),aa:Gln,seq:ttg)
     gene            complement(14659..14733)
                     /locus_tag="OPV72_002133"
     tRNA            complement(14659..14733)
                     /locus_tag="OPV72_002133"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14699..14701),aa:Gln,seq:ttg)
     gene            complement(14757..14841)
                     /locus_tag="OPV72_002134"
     tRNA            complement(14757..14841)
                     /locus_tag="OPV72_002134"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14805..14807),aa:Leu,seq:tag)
     gene            complement(14850..14926)
                     /locus_tag="OPV72_002135"
     tRNA            complement(14850..14926)
                     /locus_tag="OPV72_002135"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14890..14892),aa:Met,seq:cat)
     gene            complement(15148..16812)
                     /gene="asnB"
                     /locus_tag="OPV72_002136"
     CDS             complement(15148..16812)
                     /gene="asnB"
                     /locus_tag="OPV72_002136"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001724523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase B"
                     /protein_id="HCR9914427.1"
                     /translation="MCSIFGVFDIKTDAAELRKKALELSRLMRHRGPDWSGIYACDNA
                     ILAHERLSIVDVNAGAQPLYNAKKTHVLAVNGEIYNHQTLRAEYGDRYAFQTGSDCEV
                     ILALYQEKGPDFLDDLQGMFAFALYDSEKDAYLIGRDHIGIIPLYMGYDEFGNFYVAS
                     EMKALTPVCRTIKEFPAGSYLWSKDGEIRQYYQRDWFDYDAVKDNVTDKNALRQALEE
                     SVKSHLMSDVPYGVLLSGGLDSSVISAITKKFAARRVEDQERSEAWWPQLHSFAVGLE
                     GSPDLKAAQEVANHLGTVHHEIHFTVQEGLDAIRDVIYHIETYDVTTIRASTPMYLMS
                     RKIKAMGIKMVLSGEGSDEVFGGYLYFHKAPNAKELHEETVRKLQALHMYDCTRANKA
                     MSAWGVEARVPFLDKKFLDVAMRINPQDKMCGNGKMEKHVLRECFESYLPASVAWRQK
                     EQFSDGVGYSWIDTLKEVAAKQISDQQLETARFRFPYNTPSSKEAYLYREIFEELFPV
                     PSAAECVPGGPSVACSSAKAIEWDEAFKTMDDPSGRAVGVHQSAYQ"
     gene            complement(17102..17854)
                     /gene="nagD"
                     /locus_tag="OPV72_002137"
     CDS             complement(17102..17854)
                     /gene="nagD"
                     /locus_tag="OPV72_002137"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007373873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleotide monophosphatase NagD"
                     /protein_id="HCR9914428.1"
                     /translation="MTIKNVICDIDGVLMHDNVAVPGAAEFLTGILEKGLPLVLLTNY
                     PSQTGQDLANRFATAGVNVPDSVFYTSAMATADFLRRQEGKKAYVVGEGALIHELYKA
                     GFTITDVNPDFVIVGETRSYNWDMMHKAAFFVANGARFIATNPDTHGRGFYPACGALC
                     AGIEKISGRKPFYVGKPSPWIIRAALNKMQAHSEETVIVGDNLRTDILAGFQAGLETI
                     LVLSGVSTINDIDSMPFRPSWIYPSVAEIDVI"
     gene            complement(17901..19121)
                     /gene="nagC"
                     /locus_tag="OPV72_002138"
                     /gene_synonym="nagR"
     CDS             complement(17901..19121)
                     /gene="nagC"
                     /locus_tag="OPV72_002138"
                     /gene_synonym="nagR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator NagC"
                     /protein_id="HCR9914429.1"
                     /translation="MTPGGQAQIGNVDLVKQLNSAAVYRLIDQHGPISRIQIAEQSQL
                     APASVTKITRQLIERGLIKEVDQQASTGGRRAISIVTETRNFHAIGVRLGRHDTTLTL
                     YDLSSKVVAEEHYPLPERTQETLEHALLNTIAVFIDSCQRKIRELIAISVILPGLVDP
                     ESGVIRYMPHIQVENWGLVEALEKRFHVTCFVGHDIRSLALAEHYFGASQDCEDSILV
                     RVHRGTGAGIISNGRIFIGRNGNVGEIGHIQVEPLGERCHCGNFGCLETIAANAAIEQ
                     RVLNLLKQGYQSRVPLDDCTIKTICKAANRGDSLASEVIEHVGRHLGKTIAIAINLFN
                     PQKIVIAGEIIEADKVLLPAIESCINTQALKAFRKNLPVVRSTLDHRSAIGAFALVKR
                     AMLNGTLLQRLLES"
     gene            complement(19126..20280)
                     /gene="nagA"
                     /locus_tag="OPV72_002139"
     CDS             complement(19126..20280)
                     /gene="nagA"
                     /locus_tag="OPV72_002139"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HCR9914430.1"
                     /translation="MYALTQGRIFTGHEILDDHALVVANGLIDRVCPMAELPPGIEQR
                     SLNGAILSPGFIDVQLNGCGGVQFNDTAEAVSVETLEIMQKANEKSGCTNFLPTLITT
                     SDELMKQGIRVMREYLEKHPHQALGLHLEGPWLNLVKKGTHNPDFVRKPDAALVDFLC
                     DNADVITKVTLAPEMVPADVIAKLANAGIVVSAGHSNATLKEAKAGFRAGITFATHLF
                     NAMPYITGREPGLAGAVLDEADIYCGVIADGLHVDYANIRNAKRLKGDKLCLVTDATA
                     PAGANIEQFIFAGKTIYYRNGLCVDENGTLSGSSLTMIEGVRNLVAHCGIALDEVLRM
                     ATLYPARAIGVDKHLGSIAPSKVANLTAFTHDFKIIKTIVNGDEVVDLSK"
BASE COUNT         4672 a         5349 c         5528 g         4776 t
ORIGIN      
        1 gtcaggatta tttttcaccg ctgggctcgc aattccgttt acttgattcc agccccgcct
       61 caataaccga agctctggaa gaagcccgct cattatatct ggcttttcgc agccaattac
      121 tggagcgcca tcatctgcag ctgattctcg atcagtttga taaagctgtt atcacgcttg
      181 atgataccgg cgcgttactg cattacaata aatatgcgag ccaacttttt aaaattaacg
      241 cctccggtga aatttatgac gcatctttcc tgaaacaggt attgcaccag gagcggcata
      301 cattacgtga gggaaaaacc gtcagcgcga aagtcgtcga tacaccgcaa ggcgcgatgg
      361 tagttaatct gtatccggta tttgcggcca gacagttaag ccgggtggtg ttgacgatgc
      421 aaaccgtctc cagtttacag ggggcggaac atcatgttcg ccgccaggaa ctgtctcgcc
      481 gcggcttgag cgcccgctat catttcgacg atctgcttac cgaaaacccg gaaatgctgc
      541 gtcgtctggc gatcattaaa aattatgccg gtacggacgc gactatctta attaatggcg
      601 aaagcgggac gggaaaagag gtgctggcgc aaagtattca taatgccagc caacgcgtca
      661 acggcctgtt tgtcgccatt aactgcggcg cgatggccac tcagattctg gagagcgaac
      721 tctttggcta tgtcgccggc gcatttaccg gcgcgtcgcc gaaaggcaaa ataggcctgt
      781 ttgaattagc gcaccacggt accatttttc tggatgagat tagcgaactg gataaaccgc
      841 tacagacgcg cttattacgg gtattgcagg agcggcagat tatgcggctg ggctcagacc
      901 agatgatacc tgttgatatt cgcgtgattg cggcgaccaa tcagacgtta acgaagctca
      961 ttgcggatgg gacatttcgc gaagatcttt attatcggct taacgtatta aaagtaacca
     1021 ctatcccgct acgcaaacgt ccggaggata tcaaagccat cggcctgtcg ctgcttacta
     1081 gtttcagcca gcattataaa cgcccggcac taacgttaac cccggcgctg tggcaggagc
     1141 ttcagcgctt cgcctggccc ggaaacgtca ggcagttaag caatattatc gaacggctgg
     1201 tgctctctat tgatcactcc ccggcaactc tggatgaggg ccgcctcttg ctggacgatt
     1261 tggaagaggg gagccgacgc gagccaagta cctgccacga ctgccagatg ctggctggcg
     1321 attataaaac gattcgcctg cgtattttga gaaaattatt agaggcggaa agggataata
     1381 aatcgttagt ggcgaaacgg ttaaatgtcg atcgtacctc gctgacgcgc tggatacgcg
     1441 agtcggcctg acaagaattt acagactctg tgggcagcct tgcaaagcgt aacgcaaata
     1501 acgtctatta ttataggcag ttaacgatcc aagaggtgaa gtgatgaaca aggttgctca
     1561 atattatcgt gaactggtgg cctcattaag cgagcgttta cgcaatggcg agcgcgacat
     1621 tgatgcgctg gtggagcagg cgcgccagcg cgtgatgcaa acaggggagt taacgcgaac
     1681 cgaggtggac gaactgacgc gcgctgtcag acgcgatctg gaagagttcg ccatgagcta
     1741 cgaagagagc caggaagata gcgtcttctt gcgggtgatt aaagagagtc tctggcagga
     1801 actggcggat attaccgaca aaacccagct ggaatggcgt gaagtcttcc aggatttgaa
     1861 tcaccacggc gtgtatcaca gtggcgaagt ggtggggttg gggaatctgg tgtgcgagaa
     1921 atgccactat catctggcgg tttacacgcc ggatgtgctg ccgctctgcc cgaagtgtgg
     1981 gcacgatcag ttccagcgca ggccgtttga gccgtaaggt tcattatcgt gagcggacgg
     2041 ttgccgtccg ccatgttaag agtgtagttg ggcttccagc cggtaatagc catcggcaaa
     2101 gagtgaaaac agcggcgtca gggcggtaaa tgcttcgttc aacccgactc ctggctgatt
     2161 ccactcggca agtgaggata aaaactgcgc ggcgccttca tcatcattgc taaaaccggc
     2221 ataaacaaat tctgcgcagg ttgggcacca ggcttcagtg taaaaacgaa tcagcggcga
     2281 gccatgccag gagagcatat gaataccggc gtcagagtcg ggatcgtgga taatgcaggg
     2341 acgaagcaat gcttttccgt tacgtactga aaacgttata tgggctacgt cgtgctgtag
     2401 caggctgatt tcaggtctat tgttacgcca aaacatcgct gttcatccct ggattcttct
     2461 ttgcgcttta tgcgtagtat tgcagccgtt ccgccagcaa atcgacaaat ccctgacggt
     2521 ctacatcgac catcaccgtc gcattcggct tattccccgt caggaaataa taatccacca
     2581 ccgtcatccc ctgggtatat ttcccctgag tttccacgcc aacccaacgc tcaacggtgg
     2641 tgaaaatctc aggtttcagc agccaggcga tagtgcaagg gtcgtgcagc ggcgcgccga
     2701 caaatcccca tttttcgtct ttgtggtatt caaagaagaa gtcgagtagt tcagccacga
     2761 tcgtcgaaat tggattgccg atgtcgcgga aacgctcgat atcggcggcg tgaatctgcg
     2821 ccttatgggt gacgtccagc ccggccatca ccaccggaat gcctgactgg aagacaattt
     2881 ctgccgcttc cggatcgacg taaatattaa attccgcagc gggcgtccag ttacccagcg
     2941 ccatcgcgcc gcccatgatc acaatgcggg cgattttcgt atgcagttcc ggatggctat
     3001 tcagcagcag cgccacgttg gtctgtgggc cagtggagac gatggtgacc ggctgtgcgc
     3061 tctcgcgcag tgtttttgcc atcagctcaa cggcagtgcc gctttgcggg gcgaatgacg
     3121 gctcgggcag cgccgggccg tcaagaccgc tttcgccgtg aacgttatca gcgataatca
     3181 gttcgcgcat gagcggtttc accgcgccgc ccgccacagg aatatccggg cgtttgagca
     3241 gtgtcagcat ccgcagcacg ttgcgcagcg tcttctccgg cgtctggttg ccggcggaag
     3301 aggtgatcgc tttcacttcc agttcagggg aggcgagggc gagaacgagg gcgatcgcgt
     3361 catcatgacc cggatcgcaa tcaataataa tgggcagtgc cattgtggct ccttgtaagc
     3421 ggtactttgt gacaaggtta acgcccggct ggatacgttt cgagaagcga agaagtaaag
     3481 cgtgaggtag cgcgcactct gacgtgcgcg ccgggaagat tagtgcagga ttttcgcaag
     3541 gaagtccttt gcgcgatcgg aactggggtt agcgaagaac tcctcttttg gcgaatcttc
     3601 gacgatttta ccttcatcca taaagatcac ccggttagcc actttacggg caaagcccat
     3661 ttcgtgcgtc accaccatca tggtcatccc ttcgttcgcc agctcgacca tcacgtccag
     3721 tacctcgttg atcatttccg gatcgagcgc ggaagtcggt tcatcgaata acatggcaat
     3781 ggggtccata catagcgcgc gggcgatcgc cacgcgctgc tgctgaccgc cggaaagctg
     3841 cgccgggaac ttgttggcat gcgcagacag gccaacgcgc tccagcagct tcaggccttt
     3901 atcgcgggcg gcggccttat cgcgtttcag cactttcacc tgcgccagcg tcaggttttc
     3961 gatgatcgac aggtggggaa acagctcgaa gtgctggaat accatgccca cgcgggaacg
     4021 cagtttcgcc agatcggttt ttttgtcgtt cacaataatg ccgttaacgg taatttcgcc
     4081 tttttgcacc ggttccagac cgttgacggt cttaattagc gtggatttac cggaacccga
     4141 tggcccgcag actaccacca cctcaccttt tttcacttct gtcgaacaat cggtcagcac
     4201 ctgaaagtga ccataccatt ttgaaacatt tttcagggta atcattaaac tgtccttttc
     4261 ttcaaatagc tgaccagcaa cgacgcgctc aggctgataa caaaataaac ggcgccggcg
     4321 aacagaatca tttcgacctg agtaccgtca cgctcgccga tagtcgacgc ggtgcggaag
     4381 aagtccgcca ggctgagtac ataaactaaa gaggtgtcct gaaatagcac gatgccctgc
     4441 gtaagcaaca gcggcaccat tgcccgaaac gcctgcggca gaataatgag cttcatcgac
     4501 tgccagtggg tcatccccag cgccagcgcg gcgctggact gcccgcggga aatgctttga
     4561 ataccggcgc gaataatctc ggaatagtag gccgcttcaa acatggagaa tgccaccatc
     4621 gcggagatca ggcggatatc ggttttcggc gatagtccca gcacgttttg cagaaagccg
     4681 ggtacaatca gatagaacca cagcaagacc atgaccaacg ggatggaacg gaaaacgtta
     4741 acatacgctt tagcaaacca ggcgatagga gcaaagcttg agaggcgcat gacggccaga
     4801 atggttcccc agactatccc cacgacaacg gcggtgacgg tgatcttcag cgtgatgacc
     4861 aacccggcca gcaggtaagg cagtgagggg ataatcgaac tccagtcaaa ttcgtacatt
     4921 atttgctccc cacgttgccc ggcaggcgga ctttgcgttc aaccaggctc atgaccagca
     4981 tgataacggc gttaatcagc acataggcca gcgtaatggc ggtgaaggat tcccaggcgt
     5041 gcgccgagta atccaacagt ttgcctgcct gcgccgccat atccaccagg ccgatggttg
     5101 atgcaatagc cgagtttttc accaggttca tcatctctga cgtcattggc ggcacgataa
     5161 cgcgataggc attcggcagc aggacatagc gataagcctg cggcagcgtt agccccatcg
     5221 ccagcgccgc gttcttctgt ccgcgaggca gagactgaat cgcggcgcgc acctgttcgc
     5281 aaacacgggc ggcggtaaac agtcccagac agatcattga ggagaggaaa aactgaatat
     5341 tgggatcgag ttccgcctta aaccacatgc caagatcttc cggcaacagt tcaggcacca
     5401 ccaggtacca ggtgaagaat tgcacgatca gcggcacgtt gcggaacagt tctacgtaca
     5461 atgtgcccag tccggagagg aaacggttgg gaacggtacg taaaatgccg aaaatagatc
     5521 ctaccaggaa agcgataatc caggcggtaa tcgaaagggc tacggtgacc tgaaaaccac
     5581 tccatagcca gccgagatag gtggtattgc cgaagggggc ttcctgtaaa aaaatacccc
     5641 agttccagtc tattgacata catctactcc gaaaaaaaag ggtagcagcg ctaccctcga
     5701 agattgttgc ccggcgatct gcggtttcag gcccgatggg gaacgaccat caggcttata
     5761 gtctgtccgt gctgagcgac aatcgagagg acaggagtcc cgtcccattt agttttagtt
     5821 agttaagcgc tttatcattc ggtgctttga acagggcttt catctcgtca gacaactcga
     5881 aattcatgtt caggtttttc ggtgggatcg gatttttaaa ccacttatca aaccactttt
     5941 ccgcttcgcc ggaggtttgc gcctgagcga tggtatcgtc catcagcttt ttaaactcag
     6001 ggtcgttttt acgcagcata cagccgtagg cttcctggga ctgcggttta ccgacaatct
     6061 cccagttatc cggtttcttg gctttggcgc gctcgccggc cagcagcgcg tcatccatca
     6121 taaaggcgac ggcgcgaccg ctttccaggg tgcggaacga gtcaccgtgg tctttcgcgc
     6181 taataatacg catccccatc ttttgctctt cgttaagctt atgcagcaga atttcagagg
     6241 tcgtcccgga ggtgacgacg accgctttgc ctttcagatc cgggaaatct ttaatatcgc
     6301 cgcctttttt agtcagcagt cgcgtcccga cgacgaaaat cgtatcggag aaggcggcct
     6361 gtttctggcg ctcaaggttg ttagtcgttg aaccacattc aaaatcgaag gttccgtttt
     6421 gcaacagcgg aatacggttt tgcgaggtga tcgggatcag cttcacctgc agatcgggct
     6481 tgttaagttt cttttttacc acttccacaa tggcgttgga gtagtcctgg gaatagccga
     6541 ccactttctg ctggttgtcg taataagaaa agggcacaga agattcgcga tgcccgacga
     6601 cgatcacgcc atttttagcg atcttgtcca gggtgctacc agcggcaggc gcgccatctt
     6661 ctgcgtgcgc aaggcccgca gacagtccca tgaccagcat tgctgtggtt agcttacgta
     6721 attgcatatc caactccttt atcatctgcg ccgtcgacgc attgatagct attgtgatgt
     6781 tgttattgcc tgcaacttgc gcgtgcagtg ttatgtgtgt ttgttaacat ttagtgtggc
     6841 ttgttgtaaa tattttgctg cgatattgtt tatttttgcg aagtgcgccg caccgttcag
     6901 aggcaaaaat cgcagtttgc acaataatgg tgctaccgat gctgtgttgt ggtgcaacct
     6961 ggttgcgccg gtagggagtg tgcagcctct tgattatatt aagcaattgg cgtgccagaa
     7021 tgagattttg gtggcggtga gaggttgtag gcctgataag cgtagcgcca tcaggcacgg
     7081 tgcgatacaa ctgccggatg gcggcgtaac gccttatccg gcctacattg gatagtgcaa
     7141 tgttttattt gcggcgttga cgcaggctca tcaccagcgc gccaaagccg aacagtacgg
     7201 taatcaacca caccgtccag tcgccggttc gtgcgtacgg cgtcaggccg gtggtcggcg
     7261 tgactttggt agttagcacc tggcgtgtga actgcgggat catcgcctga atttcgccct
     7321 gcgggccaat caccgccgta ataccgttat tagtactgcg cagcaacgga cgcgccagct
     7381 ccagcgaacg catccgcgcc atctggaaat gttgccacgg gccaatggac ttaccaaacc
     7441 aggcgtcgtt agaaatcgtc agcagatagt cggtgtccgg gcggaagtta tcccgcacct
     7501 gttcgccaag aataatttca taacagattg ccgccgtcag cttatagtcg tgcgcatgta
     7561 actgcggctg gatataaggg ccgcggctaa aggaggacat gggcagatcg aagaacggcg
     7621 ccagcggacg caggatagac tccagcggaa cgaactcgcc aaagggtaca aggtgatttt
     7681 tattgtagcg attgggcgag tcataactgt atggattatc cttgcccaac gtaataatcg
     7741 tattgtaggt gtcgtatcga ttctgtttat tgagacgcgc atcgacaata ccggtgatca
     7801 gcgtgctatt tttttcgcgt aacatctcgt ccagcgaacg aaggaaaggc tgctgattga
     7861 tttcgagatc cggaatcgcc gactcaggcc agataataat ctgtgatttg cctaactctg
     7921 ggcgagtttc gttgagataa atgtttagcg tattcagtag ctggttttcg tcccacttca
     7981 gcgactgcgg aatatcgccc tgcaccagcg atacctgggt cgctttggta ggttccagcg
     8041 taaaccactg gatataacgt agcggaaagg gcaaagcaaa cagaatcacg gcgacagcca
     8101 gcggacgcca gttccgcgtc gccagtgcca gcgctaacag gccgctgacc atcatcagca
     8161 ggaagttgat cgcttcgacg cccattaccg gcgccaggcc ttttagcggg ccgtcgacct
     8221 gactatagcc aaattgcagc caggggaagc cggtcagcac ccagccgcgt aaaaattcgg
     8281 tgatttgcca tattgcaggc gcggcgatag cgacgcgcag ccagttggtt tttggccaca
     8341 ggcgcgacaa aatcccggca aacagtccgg tatacagcga gagataagct gcaagcagca
     8401 ccaccagaaa aacgttaacc gggcccggca tgccgccaaa ctgcgcgata ctgacataaa
     8461 cccagttaat cccgctgccg aaaagtccga gtccccagca atagccgatg gcggcagact
     8521 ggagcgggcg gcgattaaac gttaaggcct gcagcccgat aagcgacact atcgctgcgg
     8581 gccagacgtc atacggagag aaagccagtg ttccgcaggc gccgaataat aacgccagca
     8641 gcaggcgaat acgctggcgt tcaattaacg aggcaaatgc catttttagt ccactattgc
     8701 tgttattcgt ccagttttgg ctggggcgag tcatccggga tcctgacatg cacctgaata
     8761 atacgacgac tatcggccat tgccactttg aactggtaac catcaatgtc aatggtttcg
     8821 ccgcgggccg gtaaatggcc gaacgcctgc atcaccagcc cgccgatggt atcgacttct
     8881 tcatcgctga agtgggtgcc gaaagcgtca ttgaagtctt caatcgacgc cagcgcgcga
     8941 atcgtccagg tatggcggct aagctgacgg aagtcgatat cgtcttcttc gtcatactca
     9001 tcttcaattt caccgacaat cagttcgagg atgtcttcga tagtcacaag gccggaaacg
     9061 ccgccaaact catcgataac gatggccata tggtagcgct gggagcggaa ttccttgagc
     9121 atacggtcaa cccgtttgct ttccggtacg acaaccgcgg tacgtaacac tttgtccatg
     9181 ctgaaggctt cggcatcgct gcgcataaac ggcagcaaat ctttggccat cagaatccct
     9241 tcaatgtgat ctttatcttc gctgatcacc ggaaaacgcg agtgggcgga ctcgatgata
     9301 acatcgagac attcgtccag cgtctggttg cgtttcaggg taatcatctg ggagcgcggg
     9361 atcataatat cgcgaacgcg ctggtcggcg atgtccatta cgccttcgag catatcgcgc
     9421 gtatcttcat cgataagctc gttctgcccg gaatcacgga tcagcgccag caactcatca
     9481 cggtttttag gttcaccgtg gaaaagctgg ctgagtagca gggaaaaaaa tcccttttta
     9541 ctgtttactg tgtcactact gtgtgaattg tcgtcgctca tggcgtcgta tgggttctca
     9601 tgttagttaa tacaaagctc gtcatgcgta tactcagctg tgacggcatg ttttgcctga
     9661 tgacgctacg cttatcaggc ctacaaaagg catgaatgta ggccggataa ggcgcaagcg
     9721 ccgccatccg gcaagctact attctgcaat cttctcggca atgtacggat cctcatagcc
     9781 catagcaagc ataatctccg tttcgagaga ctccatctct tccgcttcgt catcgtcgat
     9841 atgatcgtaa cccagcaaat gcaggctacc gtgtacgacc atgtgcgccc agtgcgcctc
     9901 cagtggcttg ctctgttcct gcgcttcctg ctccacgacc tgacggcaaa taatcagatc
     9961 gcccagtagc ggcatttcaa tgccgggggg cgcttcaaac gggaaggaga gaacattagt
    10021 gggtttatct ttcccgcggt acgtcaaatt aaggtcatgg ctttcggcct catccaccag
    10081 acggattgtg acttccgcct cttcctgaaa ctgcggaata acgccgtcca gccagcgttg
    10141 aaactgagct tcatccggca ggcccgcgtg gttttcacag gccaactgta aatcgaggat
    10201 cacctggctc atttctgttc ctgctcctgg gcttcacgct tacgctccgc cgccaacgcc
    10261 gctttgcgtt tttgttcggc ctcttcccag gcttcatagg cgttcacaat gcgggcaacg
    10321 accggatggc gcaccacgtc ttcgctgtgg aagaagttaa agctgatttc atcgacttcc
    10381 gccagcactt caatggcatg acgcaagccg gatttggtgt tgcgtggcag gtcaatctgc
    10441 gtcacgtcgc cggtgatcac cgctttcgag ttaaagccga tacgcgtcag gaacatcttc
    10501 atctgttcga tagtggtgtt ctggctttca tccagaatga taaaggcgtc gtttaatgtg
    10561 cgtccgcgca tataggccag cggcgcgact tcaatcacat tgcgctcaat cagcttctcg
    10621 actttttcaa agccgagcat ttcgaacagc gcgtcataca gcggacgcag gtacgggtcc
    10681 accttctgac ttaaatcgcc tggcagaaag ccgagttttt cgcccgcttc caccgccgga
    10741 cgggtcagta gaatacggcg aatctcctgg cgctccaggg cgtctaccgc agcggcgacc
    10801 gcaagataag ttttaccggt acccgccggg ccgacgccaa aggtaatatc atgatcgaga
    10861 atattggcga tgtactgcgc ctggttcggg gtacgcggtt taatcacgcc gcgcttggtt
    10921 ttgatattaa tagctttgcc atagtcaggc acgctttccg cgctctgttc cagcacccgc
    10981 gcttctttga tcgccagatg aatttgttcc ggttcgatat cctgagtctg gccgcgcatc
    11041 ggtgcggtat cgacatacag acttcgcaaa atatctgtcg ccgcggtcac gcaaatcgga
    11101 cgaccggtca gtttaaagtg attgtcacgg cggttgattt caataccgag acgacgttcg
    11161 agctgtttaa tattgtcatc aaacggcccg caaaggctca acagacgggc gttgtctgcg
    11221 ggctcaaggg taatttcgcg agtgtctata ttcaaactgt tcctcttgtg tctgtatcgc
    11281 cggacgctga acatttaccg gcatctaagg aaattattca cgccataggg aaaaggcgca
    11341 agcattgcaa tgaagatggg gatgaagaga gaaaattgca aggcccgtcg ggcgacaggc
    11401 catgaccagg aagcccgaca ggcgtagcgc catcgggcat tattgccttt cctgcaggat
    11461 taaggctggt agaatcctac gcccagctca ttttctttac gggtacgggc aatgacggac
    11521 tccggcgttt cggcgacgcg cagacccatt tcatcttcgg tacgcaccac ttttccgcgc
    11581 agggagttcg gatagacgtc agtaatttcc acatcgacaa acttaccaat catctccggc
    11641 gtgccttcaa agttcaccac ccgattgttt tcggtacggc cagacagttc cataatgttt
    11701 ttacgcgacg tgccttccac cagaatgcgc tgtgtcgtgc cgagcatacg gcggctccat
    11761 gccatcgcct gctgattgat acgctcttgc agaatataca gacgctgctt tttctcttct
    11821 tccggtacgt catcaaccat atcggcagcc ggcgttcccg gacgcgcaga gaagataaag
    11881 ctgtagctca tatcaaagtt gacgtcggcg ataagcttca tggttttttc gaaatcatcg
    11941 gtagtttcgc ctgggaaacc gacgataaag tcagagctta tctgaatgtc cggccgcgcc
    12001 gcgcgcagtt tacggatgat tgctttatat tccagcgcag tgtgggtgcg ccccatcaga
    12061 ttcaacacgc gatcggaacc gctctgtacc ggcagatgca ggaaactgac cagctccggc
    12121 gtatcgcggt acacctcgat aatatcgtcg gtgaactcaa tcggatggct ggtggtaaag
    12181 cgaatacggt caatgccgtc gatggcggca accagacgca gcagatcggc aaaggtgccg
    12241 gtggtgccgt cgtagttttc tccgcgccag gcgttaacgt tctggcccag caggttgacc
    12301 tcacgcacgc cctgcgccgc taactgggcg atttcgaaca ggatatcgtc tgagggacgg
    12361 ctgacttctt caccgcgggt atacggtacc acgcagtaag tacaatattt attgcagcct
    12421 tccatgatag aaacgaaagc ggtcgggcct tcggcgcgcg gctccggcaa acgatcgaac
    12481 ttctcgattt ccgggaagct gatatcgacc accgggctgc ggtcgccacg cacggagtta
    12541 atcatctccg gcaggcggtg taaggtttgc gggccaaaaa taatgtcgac gtaatgggcg
    12601 cgttgacgaa tgtgctcgcc ttcctgggaa gccacacagc cgccgacgcc gataatcaga
    12661 tcgggatttt tctcttttaa cagtctccag cgacctaatt gatggaagac tttttcctga
    12721 gccttctcgc ggattgagca ggtattcaac agcagcacat ccgcctcttc cgccacgtcg
    12781 gtcagttgat agccgtgggt ggcgtccagc agatcggcca tcttcgatga atcgtactcg
    12841 ttcatctgac agccccaggt tttaatatgg agttttttag tcatcgactt gctcttgcga
    12901 aatagtggct gaaaagcagg gcgcatagtg taatgctttg gcgcggttgt gaccagtatg
    12961 actgacgtca gccctaatgg gtaaaaaatc ctgtaaactt gtctaaaacg taacaggatg
    13021 aatgaccatg acaaatcaac caacggaaat tgccattgtc ggcgggggaa tggtcggcgg
    13081 cgcgctggcg ctgggtctgg cgcagcaagg gtttacggtg atggtaatag aacatgccgc
    13141 gcctgcgccg tttgtggctg acagccagcc tgacgtgcgg atttcggcca ttagcgcggc
    13201 atccgtggcg ctgctcaagg ggctgggcgt ttgggaggcg gtgcagggga tgcgtagcca
    13261 tccttatcgg cgactggaga cctgggagtg ggaaaacgcc catgtggtgt tcgacgccgc
    13321 tgaactcaag ctgccgctgt taggctatat ggtagagaac aacgtcctgc aacaggcgct
    13381 gtggcaggcg ctggaagcgc accccggcgt gacgctgcgc gttccggctt cactggcggc
    13441 attgcaccgc cgccacgatg gttatgcgct ggaactggcc gacggcgaat gggtaacgcc
    13501 gaagttagtg attggcgccg acggcgcgaa ttcgcaggtt cggcaaatgg cgggaattgg
    13561 cattcatgcc tggcaatatg cgcagtcgtg tatgcttatc accgtcaagt gtgaaaatgc
    13621 gccaggcgac agcacctggc agcagtttac gccaacgggg ccgcgcgcct ttttgccgct
    13681 gttcgacgat tgggcgtcgc tggtgtggta tgacgctccg gcacgtattc gccagctaca
    13741 gagtttatcg atgacgcaat tgcaggtgga aattaaccag cactttccgg cgcgtctggg
    13801 ggcggtgatg cctgtcgcgg cgggcgcgtt tccgctaacc cgtcgtcacg cgttgcagta
    13861 tgcgcaaccg gggctggcgc tggtaggcga cgcggcgcat accattcatc cgctggccgg
    13921 gcagggcgtc aacctggggt atcgggatgt tgatgcgttg attgatgtgc tggcgagtgc
    13981 ccgtagctat ggcgagtcct gggccagcca ttcggtgttg aaacgctatc agacgcggcg
    14041 catggcagat aattttatga tgcaaagtgg aatggatctg ttttatgccg ggttcagcaa
    14101 tgaactgccg ccactgcgta ttttacgcaa tatggggcta atggcggcgc agcgcgcagg
    14161 cgtgctaaaa cgtcaggcgc tgaagtatgc gttggggttg tagtttgtgt tatgccgggt
    14221 ggcggctata ccttacccgg cctgtattcg cccgtaggcc tgataagcgt agcgccatca
    14281 ggctgtccga attgccagaa aagcaaaaag ctcgccgaag cgagcttttt aaaagtggct
    14341 ggggtacgag gattcgaacc tcggaatgcc ggaatcagaa tccggtgcct taccgcttgg
    14401 cgatacccca acaaattatt ttcgaaccgg tcgaatacct cgacgcgttc tgaatatggt
    14461 ggctacgacg ggattcgaac ctgtgacccc atcattatga gtgatgtgct ctaaccaact
    14521 gagctacgta gccagatgat ttcttcgatg gctggggtac ctggattcga accagggaat
    14581 gccggtatca aaaaccggtg ccttaccgct tggcgatacc ccaataccgt cgcggtgaac
    14641 cgcaaactcg aagaaatatg gctggggtac ctggattcga accagggaat gccggtatca
    14701 aaaaccggtg ccttaccgct tggcgatacc ccatccgtac aacgcttatc ggtgaatggt
    14761 gcgggaggcg agacttgaac tcgcacacct tgcggcgcca gaacctaaat ctggtgcgtc
    14821 taccaatttc gccactcccg caaaaaagat ggtggctacg acgggattcg aacctgtgac
    14881 cccatcatta tgagtgatgt gctctaacca actgagctac gtagccatct tttttcgcgt
    14941 taccttatcg gcgttgcggg gcgcattatg cgtattgagc cttgaagcgt caacctcttt
    15001 ttcatcgaaa aacgtcggaa agtgtctgtt tggttaggtt gcgaacagcg tggcgcaata
    15061 ttcggcaatt attggttatt aatcgttttt ccgaaagtgg gttgctataa aaaaagagcc
    15121 cctaggggct ctttcgtcat cgttaattta ctggtacgcc gactgatgca cgccgaccgc
    15181 gcggcctgac gggtcatcca tcgttttgaa tgcttcatcc cactcaatgg ctttggcgga
    15241 agaacaggcc acggacgggc cgccgggtac gcattccgcg gcgctcggca ccgggaacaa
    15301 ttcttcaaaa atttcccggt acaagtacgc ctctttagac gacggcgtgt tgtatggaaa
    15361 gcggaagcgg gctgtttcca gttgttgatc ggaaatctgt ttcgccgcca cctctttcag
    15421 cgtatcaatc cagctgtagc ctacgccgtc agagaactgc tctttctgac gccacgccac
    15481 gcttgctggc agataagact cgaagcactc gcgcagcacg tgtttttcca tcttgccgtt
    15541 gccgcacatt ttatcctgtg ggttgatacg catcgccacg tcgaggaatt ttttatccag
    15601 gaacggtacg cgcgcttcca cgccccaggc ggacatcgct ttgttggcgc gggtgcagtc
    15661 atacatatgc agcgcctgta gcttacggac cgtctcttca tgtaactctt tggcgttcgg
    15721 cgctttatgg aagtacaggt agccgccaaa cacctcatca gaaccttcgc cggagagcac
    15781 cattttgatg cccatcgctt tgatcttacg cgacatcaga tacattggcg ttgaggcgcg
    15841 gatagtggtt acgtcatagg tttcaatgtg gtaaatcacg tcgcgaatcg catccagacc
    15901 ctcctggacg gtgaagtgaa tttcatgatg cacggtgccg aggtggttag ccacttcctg
    15961 ggccgccttc aggtcaggcg aaccttccag acctaccgca aaagagtgca actgtggcca
    16021 ccaggcttcg gagcgctcct gatcttcgac gcgacgggcg gcgaattttt tggtgattgc
    16081 cgagataacc gacgagtcca ggccgccgga gagcagtacg ccgtagggca cgtcggacat
    16141 caggtggctt ttcacggatt cttccagcgc ctgacgcagc gcgtttttgt cggtgacgtt
    16201 atcttttacc gcatcgtaat cgaaccagtc gcgctgatag tactgacgaa tttcgccgtc
    16261 tttgctccac aggtagctgc ccgccgggaa ctctttaatg gtgcggcaga ccggagtcag
    16321 cgctttcatt tctgacgcta cgtagaagtt gccgaattcg tcatagccca tgtagagcgg
    16381 aataataccg atatggtcac gaccaatcag ataagcgtct ttttcgctgt catacagggc
    16441 gaaggcgaac atcccctgta aatcgtcaag gaaatccggc cctttttcct gatatagcgc
    16501 gagaataact tcgcagtcgg agccagtctg gaacgcgtaa cgatcgccat actccgcgcg
    16561 taacgtctga tggttataaa tttcaccgtt caccgccagc acgtgagttt tcttagcgtt
    16621 atacaggggc tgggcgccgg cgttaacatc aacaatcgac aagcgttcat gtgcgagaat
    16681 cgcgttatcg caagcgtaga tgccggacca gtccgggccg cgatggcgca tcaggcgtga
    16741 caattcaagg gcttttttac gcagttccgc tgcatctgtt ttgatatcga atacgccgaa
    16801 aatagaacac atagccttct ccgttaatct gttgcgtcgt actttttgtg tttgcttgac
    16861 taaaaaatgc cgcaaaggcg tggaaggcgc aaggggatta cggtctgaaa aatgaaaaac
    16921 gcaatcgtca ttgttgatta gtgaaaaatg attacgtatt gcgcgaattt attgatgaat
    16981 cttcagtttt atagtggttt aattgaatta tgtttttcct gatgacgttt cgcttatcag
    17041 gcctacaatg ttgttcgaac cgtaggcctg aaagcggcgc gtcatcaggc aggggacagg
    17101 tttagataac gtctatctcg gcgacggaag ggtaaatcca gcttgggcgg aacggcatac
    17161 tgtcaatatc attgattgtt gatacgcctg aaagcaccag aatggtctcc agaccggcct
    17221 ggaaccccgc cagaatgtcg gtgcgcaggt tgtcgccgac gataacggtc tcttccgagt
    17281 gcgcctgcat tttgtttaac gccgcgcgga tgatccacgg gctgggtttg ccgacataaa
    17341 acggcttccg gccggaaatt ttttcaatgc ctgcgcacag cgcgccgcag gccggataaa
    17401 agccgcgacc gtgggtatcc gggttggtgg cgataaagcg cgcgccatta gcgacgaaaa
    17461 atgctgcttt atgcatcatg tcccagttgt aggagcgggt ctctccaacg atgacaaaat
    17521 cagggtttac atcggtaatg gtaaaacccg ctttatagag ctcgtgaata agcgcgcctt
    17581 cgcccacgac atacgctttt ttaccttcct gacggcgcag aaaatcggct gtcgccattg
    17641 ctgacgtata aaacacgctg tccggcacgt taacgccagc ggtagcaaaa cggttcgcca
    17701 gatcctggcc ggtttgcgac gggtaattgg tcagcagcac cagcggcaga cctttttcca
    17761 gaatccccgt cagaaattcc gccgcaccgg gtacggctac gttgtcgtgc atcagcacgc
    17821 cgtcgatatc gcagattaca ttcttgatgg tcatgaacta cccagggaat ttgtgaataa
    17881 tccgatacta taagagcgca tcagctttcc agcaaacgtt gcagcaatgt tccgttgagc
    17941 atggcgcgtt taactaaggc aaatgcgccg atagcagaac ggtgatccag cgtggagcgt
    18001 accaccggca aatttttgcg aaaggccttt aacgcctgcg tattgataca gctttcgata
    18061 gcgggcaaca ggactttatc ggcttcaatg atctcgccgg caatgacgat tttttgcgga
    18121 ttaaacaggt tgatagcaat ggcgatcgtt ttgcccaaat ggcggccaac atgctcaatg
    18181 acttccgagg ccaggctgtc gccccggttt gccgccttac agatggtttt aatcgtgcag
    18241 tcgtcaagcg gaacacggct ttgataccct tgtttaagca aattcagcac ccgttgttca
    18301 atcgccgcat tggcggcaat ggtttccaga cagccgaaat taccgcagtg gcagcgctcg
    18361 cccaacggct ccacctgaat atgcccaatt tcgccgacgt tgccgttacg gccaatgaag
    18421 atgcgtccgt tggagataat cccggcacct gtaccacgat ggacgcgcac cagaatcgag
    18481 tcctcgcaat cctgactggc gccgaagtag tgttccgcca gtgccaggct acgaatatcg
    18541 tgacccacga aacaggtaac gtgaaaccgt ttttccagcg cttcgaccag tccccagttt
    18601 tcaacctgaa tgtgcggcat gtaacgaatc acgccgcttt ccggatcgac aagccctggc
    18661 aggatcaccg agatagcgat caattcacga attttacgct gacaactatc aataaagacg
    18721 gcgatagtgt tgagcagcgc atgttccagc gtctcctggg tgcgctccgg cagcggataa
    18781 tgctcctcag cgaccacttt actgctcaga tcgtagagcg ttaaagtggt gtcatgacgc
    18841 cccaggcgaa cgccaatggc gtggaagtta cgggtttccg tgacgataga gatagcgcgg
    18901 cggcctccgg tagaggcctg ctgatcgact tctttgatca gcccgcgttc aatgagttga
    18961 cgcgtaattt tcgttacgct ggcgggagca agctggcttt gctcggcaat ttgtatgcgc
    19021 gagataggac catgctggtc aatcaggcgg taaacggccg cgctgttaag ctgttttacg
    19081 agatcaacgt tacctatctg agcttgtccg cctggtgtca tattctcact tactcaagtc
    19141 aacgacctcg tcaccattaa cgatggtctt gataatttta aaatcgtggg tgaacgcggt
    19201 caggttggcg actttactcg gcgcaatgct accgagatgc ttatcaacgc cgatagcgcg
    19261 tgccggatag agcgttgcca tgcgcagcac ttcatccagc gcgatgccgc aatgcgcgac
    19321 caggttgcgt acgccttcaa tcatggttaa ggacgaaccg ctcaacgtac cgttttcatc
    19381 cacacacagt ccattgcggt agtatattgt tttacctgcg aaaatgaact gctcaatatt
    19441 ggcccccgcc ggtgcggtgg cgtctgtcac cagacaaagt ttgtcgcctt tcaggcgttt
    19501 ggcattgcga atgttggcgt agtcgacatg cagaccatcg gcgataacgc cgcaataaat
    19561 atccgcttcg tccagaacag cgccagcaag gcccggctca cgccctgtaa tgtacggcat
    19621 cgcgttaaac aggtgagtcg caaaggtaat cccggcgcgg aagcccgctt ttgcctcttt
    19681 taacgtcgcg ttggagtgac ctgcggaaac cacaatgccc gcattcgcca gtttagcgat
    19741 tacgtcagca ggcaccattt ccggcgcgag agtgactttg gtgatgacgt cggcattatc
    19801 gcataagaaa tcgaccagcg cagcgtctgg tttacgcacg aaatcaggat tatgggtgcc
    19861 tttttttacc agattaagcc aggggccttc caggtggaga cccagcgcct ggtgcggatg
    19921 tttttccaga tactcgcgca tgacgcgaat accctgtttc atcaattcgt cgctggtagt
    19981 gataagcgtt ggcagaaagt tagtacagcc cgatttttca ttggctttct gcataatttc
    20041 cagcgtttca acgctgacgg cttctgcggt atcgttaaac tgcactccgc cgcagccgtt
    20101 tagctgcaca tcaataaaac cgggggagag aatggcccca ttcaatgagc gttgttctat
    20161 tcccggcggc agctcggcca tcggacaaac gcggtcaatc aggccattag cgacaacaag
    20221 cgcatggtca tcaagaattt cgtgaccggt aaagatccgg ccctgggtta aagcatacat
    20281 tctgaccccc gatatcaaaa atttaccgcc ccgcattgac tggcg
//
LOCUS       DAJVBX010000069        20287 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.069, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000069 DAJVBX010000000
VERSION     DAJVBX010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 20287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20287
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.069"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            109..327
                     /locus_tag="OPV72_002140"
     CDS             109..327
                     /locus_tag="OPV72_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015406347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hin recombinase"
                     /protein_id="HCR9914431.1"
                     /translation="MECELIVERTSAGLEVVRSKGRIGGRRPKLTPEQWEQAGRLLAA
                     GETRHRVGLLFDVSISTLYKKFPVNQSR"
     gene            430..1602
                     /locus_tag="OPV72_002141"
     CDS             430..1602
                     /locus_tag="OPV72_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath protein"
                     /protein_id="HCR9914432.1"
                     /translation="MAQDYHHGVRVVEINEGTRPITTVSTAIVGMVCTGDDADASVFP
                     INKPVLLTDVLTASGKAGESGTLARSLDAIADQAKPVTVVVRVAQGETEAETTSNIIG
                     GVTSDGKKTGMKALLSAQSQLGVKPRILGVPGHDTQAVATELLGVAQSLRGFAYLAAN
                     GCKTVEEAIAYRENFSQREGMLIWPDFINFDTVLKADATAYASARALGLRAKIDEQIG
                     WHKTLSNVGVNGVTGISADVFWDLQDPATDAGLLNKNDVTTLIRKDGFRFWGSRCLSD
                     DPLFAFENYTRTAQVLADTMAEAHMWAVDGVLNPSLARDIIEGLRAKMRSLVNQGYLI
                     GGDCWLDESVNDKDTLKAGKLTIDYDYTPVPPLENLMLRQRITDRYLVDFASRVAA"
     gene            1612..2127
                     /locus_tag="OPV72_002142"
     CDS             1612..2127
                     /locus_tag="OPV72_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail tube protein"
                     /protein_id="HCR9914433.1"
                     /translation="MALPRKLKHLNLFNDGNNWQGIVESLTLPKFTRKFEKYRGGGMP
                     GAVDVDMGLDDGALDTEFSIGGTELLLFKQMGKATVDGIQLRFTGSIQRDDTGEVQAV
                     ELVVRGRHKEVDSGEWKTGESSSTKVSSTNSYAKLTINGEVLYEVDLVNMVEIVGGVD
                     LMEEHRNALGL"
     gene            2182..2484
                     /locus_tag="OPV72_002143"
     CDS             2182..2484
                     /locus_tag="OPV72_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001528658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly protein"
                     /protein_id="HCR9914434.1"
                     /translation="MSDKLTEKTVKLDTPIMRGKTEITEIVLRKPQSGALRGTRLQAI
                     MDMDVGAMMTVIPRISSPTLTAQEMAELDPADLTAMAVEVVTFLLPKSVLADLPTT"
     gene            2499..2618
                     /locus_tag="OPV72_002144"
     CDS             2499..2618
                     /locus_tag="OPV72_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GpE family phage tail protein"
                     /protein_id="HCR9914435.1"
                     /translation="MADIATIFHWSPSITDVMPLTDVLEWRHKAIQRSGASDE"
     gene            2611..5391
                     /locus_tag="OPV72_002145"
     CDS             2611..5391
                     /locus_tag="OPV72_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004134619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HCR9914436.1"
                     /translation="MSDNNLRLQVVLGAVDKLTRPFKNAQAGSKELASAIRQTRDQIK
                     KLSDAGGQLKSFDQLTQSVSRTGAELDQARLRAQMMTREMSSLESPTKKQTQALEAQW
                     RAVSRLEQKQQQETRQMAAARAELYRLGLSAGGGARETARIARETERYNRQLAEQERR
                     LREVGERQRKLNAIKAKAEKTRELRNSLAGNGAGAMAAGVTTGMTLLAPVKAYSESEN
                     AANQLAGSMMGPGGKVAPEFEKINRLAVALGDKLPGTTADFQNMMTMLRRQGMSAQVI
                     LGGLGESAAYLGVQLQMAPTAAAEFAAKLQDATQTSEKDMMNLMDVIQKGFYAGVDSG
                     NMLQGFSKISSAMNIINKKGLEAVKTFAPLLVMADQGSMAGESAGNAYRKIFQAALDA
                     DNIKAVNDDLKEKGAGIKFNFSDGKGGFGGLENMYAQLEKLKKLNPETQMATMKDLFG
                     NDAETLQALNIMLSKGIEGYRETAAKLENQASLRERVDASLNTLGNKWEAATGTFTNA
                     MASIGETVAPALKNLADWLGELASRLDGFVKRHPSLTSALFKMAAGFAVAATAVGAIS
                     LALASILGPMAIIRVSAGMLGLKFASVGGLVRAALGGLGKSVLWLGRLMFANPILAVI
                     GLIAAGAIYIWQNWDTLGPKFKAMWDAVCNATGTAWDWIKEKASAAWEGIKSLFFNYT
                     LPGLIAKNWDAIKSGVSEAWANIRQSISDKWNAILADVSALPAKFQDTGSAIIDSILD
                     GINAKWETLKSKLSSVTDYLPDWMTENNKTQDKAQVQVVGGAAAAAVPFAGMYDSGGI
                     IPRGQFGIVGENGPEIVNGPAKVTSRRRTAALASIVAGVMGVAAAPAEAAPLHPYSLP
                     TAAYKQSQPAKSASAPPVMHFETHAPITIYAQPGQSAQDIAREVARQLDERERKTRAK
                     ARSNFSDQGGYE"
     gene            5391..5876
                     /locus_tag="OPV72_002146"
     CDS             5391..5876
                     /locus_tag="OPV72_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCR9914437.1"
                     /translation="MMMVLGLYVFMLRTVPYQELQYQRSWRHAANSRVNRRPSTQFLG
                     PDNDPLTLSGVLLPEVTGGRLSLLALEQMAELGKAWPLIEGSGTIYGMFVIESLSQTK
                     TEFFESGMSRRIEFTLTLKRVDESLSDMFGSLSDQLSNLQDSATSAIGNIKNTVGGLL
                     Q"
     gene            5873..6973
                     /locus_tag="OPV72_002147"
     CDS             5873..6973
                     /locus_tag="OPV72_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage late control D family protein"
                     /protein_id="HCR9914438.1"
                     /translation="MNFSSDLFGLNSRSPAFSITIEGKDVTTALDARLMSLTLTDNRG
                     FEADQLDLELDDADGQIVLPRRGAVIQLALGWKGQPLFPKGAFTVDEIEHSGAPDRLT
                     IRARSADFRETLNTRREKSWHQTTVGEVVKEIAARHNLKVALGKDLTDKVLDHMDQTN
                     ESDASFLMKLARQYGAIASVKDGNLLFIRQGQGRTASGKPLPVITITRKAGDGHRFTL
                     ADRGAYTGVIASWLHTREPKKKETTQVKRRHKKVATPKEPEAKQGDYLVGTDENVLVL
                     NRTYANRGNAERAAKMQWERLQRGVASFSLQLAEGRADLYTEMPVKVSGFKQPIDDAE
                     WTITTLTHTVSPDNGFTTSLELEVKIDDLEIE"
     gene            7041..7259
                     /locus_tag="OPV72_002148"
     CDS             7041..7259
                     /locus_tag="OPV72_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019704608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ogr/Delta-like zinc finger family protein"
                     /protein_id="HCR9914439.1"
                     /translation="MMNCPKCGHSAHTRSSFQVTDSTKERYCQCQNINCGSTFVTHET
                     VVRFIVTPALVNNAPPHPTVSGQGHMNF"
     gene            complement(7346..7723)
                     /locus_tag="OPV72_002149"
     CDS             complement(7346..7723)
                     /locus_tag="OPV72_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001039750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914440.1"
                     /translation="MNKPLIALLLITSFSASADKIPSSIQNLIAVYDTRTHSLEDGGL
                     TIRYNKRLLLVDAAESMFQGICNDYYMNKWKPGTIKRITLLNVTSDQGFEINAGGDEC
                     RKAGTMKDEQARTYRTSFIKPLQ"
     gene            7857..7943
                     /locus_tag="OPV72_002150"
                     /pseudo
     CDS             7857..7943
                     /locus_tag="OPV72_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490545.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
     gene            7943..9217
                     /locus_tag="OPV72_002151"
     CDS             7943..9217
                     /locus_tag="OPV72_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000457546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HCR9914441.1"
                     /translation="MFALADVNSFYASCEKVFRPDLRNTPVVVLSNNDGCVIARSKEA
                     KQLGIKMGVPWFQLKTTEFPVPVVAFSSNYELYASMSNRVMAHLEELAPRVEQYSIDE
                     MFLDVRNIDSCIDFEDFGRQLREHVHSGTGLTIGVGMGPTKTLAKSAQWASKEWRQFE
                     GVLALTSGNPKRTEKLLSLQPVDEIWGVGRRISKKLHTMGITTALQLARANPTFIRKN
                     FSVVLERTVRELNGESCISLEEAPPPKQQIVCSRSFGERVTTYEAMRQAVCQYAERAA
                     EKLRGERQFCRHVAVFVKTSPFAVNEPYYGNVASEKLTTPTQDTRDIIAAAVKALDRI
                     WVKGHRYAKAGCMLNDFTPTGISQLNLFDEVQPHERSEQLMKVLDSINHSGMGKVWFA
                     GRGIAPEWQMKRELLSPAYTTRWAELPVARLR"
     gene            9349..9618
                     /locus_tag="OPV72_002152"
     CDS             9349..9618
                     /locus_tag="OPV72_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001222413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914442.1"
                     /translation="MRINVLLLTSLLVAGPALAGEAHVCKSQTVANSAANAELTDNTV
                     FKCGESISGTIPSLAREGWKIVQQTDQADVTDPSKTYAQLIIQKD"
     gene            complement(9718..10044)
                     /locus_tag="OPV72_002153"
     CDS             complement(9718..10044)
                     /locus_tag="OPV72_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000911568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3085 domain-containing protein"
                     /protein_id="HCR9914443.1"
                     /translation="MLKFSAKDLKPVLLEARKNHCGVVLVKDHGVYIMSETGELTPRG
                     RKVAYAKGCHPEKDEAWWDTARAEVGGDDFGETINLTKSMINRILNERKPLYITASNE
                     EFKIEC"
     gene            complement(10119..11018)
                     /locus_tag="OPV72_002154"
     CDS             complement(10119..11018)
                     /locus_tag="OPV72_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914444.1"
                     /translation="MSIIDEYISQHFSERLCLDVTEEDITWQLRGSRSDYVNTRIQFD
                     REKLMAVMDVMLSGLDSDETTLARCRQVLTLWIAGLDMLSKEAEQPDWLPRVHPHSSG
                     QCDLLLKGNPAALTEADEETYLRVTGQQDLPAHRRIPQVIFSKTVRYWHRFESWLAQQ
                     LQDITQHCYQKLKCFVANCTTEPRQLREFRGEYGSLRLFVGPQDIDEIDILEFNPEYI
                     VSWVDKVADGLFTPVCFVVNVYYKNGILLESFTWDSEVDNINRMTSSDYGEAMSQAIS
                     WVREQFEQPVIDQPVPQQPRLAA"
     gene            complement(11092..12000)
                     /locus_tag="OPV72_002155"
     CDS             complement(11092..12000)
                     /locus_tag="OPV72_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914445.1"
                     /translation="MLASFYIQRQLSKALGLSVNAEEVFYQVDDRESDYVNTDMVLNR
                     DRLLSVMQFMLDDVALNPELRERCRQAERILTLWIRGLDALATVSEDMSILPRTITEC
                     SGRVDRLLPGDPQALLALPDDAFLRLTAQCHLMSGEQFPREQLAATMPYWTRFMAWIA
                     RELYQVEDRCLVQLGRLYRRLHVEPRKIRCFNLAFGRIELHMSGRDIDECQYLYAYDD
                     ASLEDYLEEIMAGNLTPVRFEVRVIYRNDSELNVFRRDADVIDVEHPHVSDWQNVVSE
                     ALDWLRQERTSLVEIPLTRPALKLAA"
     gene            complement(12072..14021)
                     /locus_tag="OPV72_002156"
     CDS             complement(12072..14021)
                     /locus_tag="OPV72_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1738 domain-containing protein"
                     /protein_id="HCR9914446.1"
                     /translation="MNTSLHPDDISRFISGRLISSLAAGQVPWRGTIPGLPEHALTGV
                     PFTGINVLLLWQAMQQRSLRSGRWLTGDDLRQLGGQVRSGEKPVTLVRYRPSLSLFKV
                     INPEQCDGLPDTLQPGWPLPPRPQPSLNVIRDLLQNSGVPVIHRDNVLPVYRALHDRI
                     ELPPVASYVGEETYWQDILNLLVQATGHPQRLHRFGLTVDTRTDEVHEALVAELGAAF
                     LSAALGLPGAMLSRLDVAPWVTYLQGDPWRLFRAAEAARKAMMWLKERRPSMTTVEMW
                     QKMASLILETHYGFSLDDTTLGCRSVVERHIECGITPLMAINALARIYQWERYDQPQR
                     SLFINEAGPDSEILTLSEIRPELLTCYRVPVPSGIPDRKAEAVQVESLPLLLAPAVSE
                     GKSAANDDGPDDPDGNDNVVALPWAARRGKENPHIHRFVSIFNGIAPHESRWQVFSDF
                     VHMAACSLYNAVHRDPDFEADYMRRVSHYSAEDANNMARLLSEVVMGLEFSPTDFLGR
                     IYMISGLGNFHNAQYFTPYSVSYAMARMTLSDRIPELSSGERDFITVSDPASGAGSMV
                     VALAEAMLEAGFNPQKQMVAYCVDIDPVASMMCYIQLSLMGIPAIVATGNSLTVEIKR
                     EMATPMFVLGRWHHRWQADRTRKAA"
     gene            complement(14110..14568)
                     /locus_tag="OPV72_002157"
     CDS             complement(14110..14568)
                     /locus_tag="OPV72_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000115421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914447.1"
                     /translation="MSVMTTNETPASTVAEPEVFRRTRNRFNQWLQAEFDRHYHTMRD
                     GGYRSFLKKNHPTELLRYDEACEALRREEFARFAELQTLGLYLHLQVQQKEAQFRRRR
                     NRLLLGMTLTGVVTSVLLYGHFHPEQFLLIGQELATLPGRILGFVGRLVP"
     gene            complement(14646..14942)
                     /locus_tag="OPV72_002158"
     CDS             complement(14646..14942)
                     /locus_tag="OPV72_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914448.1"
                     /translation="MMDIMALLSSTPPAVAIEEPVWEQLVKYPQAPDCENERLQRLIY
                     HGFQALSQAPSGQGIVEFGYFCLPPDGDLHAPLWQNVCIKREYSDGQVTLTFDR"
     gene            complement(14939..15391)
                     /locus_tag="OPV72_002159"
     CDS             complement(14939..15391)
                     /locus_tag="OPV72_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000979718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914449.1"
                     /translation="MMLTTRLFVFLLHHLWRVMRWTGLTVYHGISVLYRRRQARLQAS
                     DWRPRTVYTGRWQLADDGQFCGRAVVLRLRDALKPGVELLYFGEEAAEPYYSERQFVD
                     DRESVMVAEQMLLRFLGSRHRRQNRRNAPVSVLVTDVVTTAPVNDEAA"
     gene            complement(15409..15618)
                     /locus_tag="OPV72_002160"
     CDS             complement(15409..15618)
                     /locus_tag="OPV72_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000018146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914450.1"
                     /translation="MSHIHLPSVCEKTGNTLTPEQENRVRHLVHEECYSRDRAALIKL
                     IGLMLLLKLAGTLMLAMLLLVLRLF"
     gene            complement(15989..16369)
                     /locus_tag="OPV72_002161"
     CDS             complement(15989..16369)
                     /locus_tag="OPV72_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914451.1"
                     /translation="MNVYQLKNRTDVLIWLSLIEGDLLSIQASLNAGLYPLYDDRQEE
                     PEFECAVFNCGMAFGEFMERLESEDIDVLTTAGHELTGSIEHMGRMLCEPVWTQAVLL
                     GRNEARADRAICAAEADGWLYDPA"
     gene            complement(16465..16767)
                     /locus_tag="OPV72_002162"
     CDS             complement(16465..16767)
                     /locus_tag="OPV72_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914452.1"
                     /translation="MNIFLTSLVSILRKALPRIRHGKSEWIANHTGYLRFQAEVWLDD
                     NDHFHAVVNKRSGWMNPRYEQVVDCGKFDSFHCAMNTAYSQALELAHLRYAWELTD"
     gene            complement(17491..18411)
                     /locus_tag="OPV72_002163"
     CDS             complement(17491..18411)
                     /locus_tag="OPV72_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase domain-containing protein"
                     /protein_id="HCR9914453.1"
                     /translation="MAGKTARSKVEKFRRDFVTLARDAGRAYATAADSMRIAKYFLNY
                     LRDNGIKLRHTDSIKTRHVTGYLQFRKSQGISVRTIQNERAAIRGVLNKAGRYKLADP
                     NNPLLSNKALGLEKSSRSGTKLPLSPEEFQKAFKEVEKSNRGVAATMLLSYTLGLRTK
                     EAVESCKSVMTWKRALESGEHSVRVIFGTKGGRGRNTLIVDKDALRHAINYAEKVMKE
                     NNGKLIDRPDIRKAIDTYRYHVRRAGLTGEKAPHSMRYHFSQEAREYYEKNGFSGKEI
                     YAQVSMDLGHGDGRGRYVKQVYFRDGTEDE"
     gene            19677..20219
                     /locus_tag="OPV72_002164"
     CDS             19677..20219
                     /locus_tag="OPV72_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010989295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1062 domain-containing protein"
                     /protein_id="HCR9914454.1"
                     /translation="MKVTWTVTPVGYQHIAKRCPSCNVKRDFTPSGAFRINSQKKILD
                     VWSIYKCTHCDYTWNIALYSRLPVSKINQELHHRLMTNDESTIRHFAYDTAVLKQNNA
                     KLSGQLDFRIQERCLTSITRQYQICVRIRLTRSFQVSLLSIMKIQLMLSSADIRRRID
                     SGQITGVTAKMLKSRKLRQT"
BASE COUNT         5191 a         5163 c         5181 g         4752 t
ORIGIN      
        1 aattcggctg attcaattaa tgctacaaat agtactattt ttattttcca gaaactttca
       61 aaaaaagtcc ttttcgctca ggaggagcct tgccgttctg gcattgaaat ggagtgtgag
      121 ctgatcgttg agcgtaccag cgccgggttg gaagtggtgc gttcaaaagg tcgtattggt
      181 ggcaggcgtc caaagctcac cccggaacaa tgggagcagg ccggacggtt gcttgccgcc
      241 ggtgaaactc gtcatcgtgt tggattgctt tttgatgtta gcatttccac tctttacaag
      301 aaattccctg taaatcagtc gcgttgaaag tggcgatatt gtaccagcac tgacacatcg
      361 tgaaatacgt gcgccgcacg cctggcaacc agaacataag gtatccctgt caaccggaga
      421 gactgcctta tggctcagga ttaccaccac ggggtgcgcg ttgttgaaat caacgagggc
      481 acccgaccta ttaccacggt gagcactgcc atcgtgggca tggtctgcac cggcgatgat
      541 gctgatgcgt ccgtgttccc catcaataag cctgtcctgc tgactgatgt gctcaccgcc
      601 agcggtaaag cgggggagtc cggcacgctg gcccgctcgc tggacgcgat tgcagatcag
      661 gcaaaacccg tgactgtcgt tgtgcgtgtg gcgcagggcg aaaccgaagc ggaaaccacc
      721 tccaatatta tcggcggcgt aacttccgac ggtaagaaaa cgggcatgaa agcgctactg
      781 tcggcgcagt cgcagctcgg tgtcaagccg cgcattcttg gggtgccggg acatgacact
      841 caggccgttg ctactgaact gctgggcgtg gcgcaaagct tgcgcgggtt tgcctacctt
      901 gctgctaatg gctgcaaaac ggtggaggaa gctattgcct atcgcgagaa tttcagtcag
      961 cgcgagggaa tgctgatctg gcctgacttc atcaactttg acaccgtgct gaaagcagac
     1021 gcgacggctt acgcctccgc ccgtgcgctc ggcctgcgtg ccaaaatcga cgagcagatc
     1081 ggctggcata aaaccctgtc caatgtgggt gtgaacggtg tcaccggcat ttccgctgat
     1141 gtgttctggg atctgcagga cccggcaacc gatgcgggac tgctgaacaa aaatgacgtc
     1201 accacattga tccgcaaaga cggcttccgc ttctgggggt cccgttgtct cagtgacgat
     1261 ccgctgtttg cctttgagaa ctacacccgc acggcgcagg tgctggctga cactatggcg
     1321 gaggcgcaca tgtgggcggt ggatggcgtg cttaatccgt cgctggcccg cgacattatt
     1381 gaaggactac gcgccaagat gcgcagtctg gtcaaccagg gatacctgat tggtggtgac
     1441 tgctggctgg atgagtctgt taacgataaa gacaccctta aagccgggaa actgaccatc
     1501 gattatgact acacgccggt gcctccgctt gaaaacctga tgctgcgcca gcgcatcacc
     1561 gatcgttacc tggtcgattt tgccagccgt gtcgctgcat aagggggaat catggcttta
     1621 ccacgcaagt taaaacacct gaacctgttc aacgacggga acaactggca ggggatcgtt
     1681 gagtccctga ccctgccgaa attcacccgc aagtttgaga agtatcgcgg cggcggtatg
     1741 ccgggcgcgg tggacgtaga catggggctg gatgacggcg cactggacac ggaattttca
     1801 atcggcggca ccgaactgct gttattcaag cagatgggca aggcaaccgt tgacggcatc
     1861 cagttgcgtt tcaccggttc cattcagcgt gacgataccg gcgaagtgca ggccgttgag
     1921 ctggttgtgc gcgggcgtca taaagaggtg gattccggcg agtggaaaac cggcgagagc
     1981 agcagcacca aagtcagcag taccaacagc tacgcgaagc tgaccattaa tggtgaggtg
     2041 ctctatgagg tcgatctggt caacatggta gaaatcgttg gcggcgtgga cctgatggaa
     2101 gaacaccgta atgccctcgg cctctgatta accttaacgg cgcgggcagc cgcgccagta
     2161 tttcattaac aggaaacgaa catgagcgac aagctgactg aaaagaccgt aaaactggat
     2221 acccccatca tgcgcggtaa aactgaaatt accgaaattg tgctgcgcaa gcctcagtcc
     2281 ggcgcgctgc gtggcacccg tctgcaggcc attatggata tggacgtggg cgcgatgatg
     2341 actgtgatcc cgcgaatctc ttccccgacg ctgaccgcgc aggaaatggc agagctggac
     2401 cccgccgatc tgacagcaat ggctgtagag gtggtgactt ttttgttgcc gaagtcggtg
     2461 cttgccgatt tgccgacaac ctgacggttg atgatctggt ggcagacatt gccaccatct
     2521 ttcactggtc gccgtccatc actgacgtta tgccgctgac tgatgtgctg gagtggcggc
     2581 ataaggcaat tcagagaagc ggggccagcg atgagtgata ataacctgcg actgcaggta
     2641 gttctggggg cggtggataa gttaacccgc ccatttaaaa atgcacaggc tggctctaag
     2701 gagctggcat cagctattag acaaacccgc gatcagatta aaaagctgag tgatgctgga
     2761 ggtcagctta aatctttcga tcagctaact caaagtgtta gccgtactgg tgccgaactg
     2821 gatcaggcga ggctacgcgc tcaaatgatg acgcgcgaaa tgtcttcttt ggaatccccg
     2881 acaaaaaaac aaacgcaggc gcttgaagct cagtggcgtg ctgtttcacg tcttgaacaa
     2941 aaacagcaac aggaaactcg ccagatggcg gcagccagag ctgagcttta tcggctgggg
     3001 ttatctgctg ggggcggagc gcgtgagacg gcacggattg cacgagaaac tgagcggtat
     3061 aaccgacagt tggctgagca ggagcgcagg ctgcgtgaag ttggcgagcg tcagcgaaag
     3121 ctcaacgcca tcaaagccaa ggctgaaaag acccgcgagt taaggaactc tctggcaggt
     3181 aatggtgcag gggcgatggc ggctggggta actactggca tgacgttgct ggctccagta
     3241 aaagcctatt cagaatcaga aaatgcagcg aatcaactcg ccggttccat gatggggccg
     3301 ggcggaaagg tagcgcctga atttgaaaaa attaaccggc ttgcagttgc tttgggtgat
     3361 aagctgccgg gaacaacagc cgactttcag aacatgatga ctatgctacg ccgtcagggt
     3421 atgtcggcgc aggtcatcct gggaggcttg ggagagtcag cagcttatct tggcgtgcag
     3481 ttacagatgg ctcccactgc agcagctgag tttgcggcta agttacaaga tgctactcag
     3541 acctccgaaa aagacatgat gaatctgatg gacgtgatcc agaaaggatt ctacgcgggg
     3601 gtagattcag gaaatatgct gcagggtttc tcaaaaatca gcagcgcgat gaatatcatc
     3661 aataagaagg ggttggaagc ggtcaaaact ttcgcgcctt tgttggttat ggctgatcag
     3721 gggagtatgg ctggtgagtc tgccggtaat gcataccgaa agatttttca ggccgctctg
     3781 gatgctgaca atattaaggc ggttaacgat gacctgaaag aaaagggcgc gggtattaaa
     3841 ttcaacttct ctgacgggaa gggtgggttt ggtggtctgg aaaatatgta tgcccagctg
     3901 gagaaactta aaaaattaaa tccagaaacc caaatggcaa ccatgaaaga tttgtttggc
     3961 aatgatgcgg aaacgctaca agcgctgaac attatgctat ctaaagggat tgaaggatat
     4021 agagaaactg cagcaaagct tgaaaatcag gcatcgctta gggagcgtgt tgatgcatcg
     4081 ctgaacaccc tggggaataa atgggaggct gctaccggga cattcactaa tgcgatggcg
     4141 agtattggtg aaaccgtagc acctgcatta aagaacctcg ccgattggct gggggagtta
     4201 gcctctcgtt tggacggttt tgttaaacgc catccctcgc ttacgtctgc cttattcaag
     4261 atggctgcag gatttgccgt tgctgcaacg gctgtagggg ctatctcttt ggcgctggca
     4321 tcaatccttg gtccgatggc aatcatcaga gtgagcgcgg gcatgttggg cctgaagttt
     4381 gcgtcggtgg gtggcttggt tcgtgctgcg ctgggagggc tcgggaaatc agttttatgg
     4441 ctgggccgat tgatgtttgc aaaccctata ctggctgtca tagggctgat cgccgctggt
     4501 gctatttata tctggcagaa ctgggacacg cttgggccaa agttcaaggc catgtgggat
     4561 gccgtatgta atgccacagg tacggcatgg gattggatta aagaaaaggc cagcgccgcg
     4621 tgggagggga ttaagtcact gttctttaat tataccttgc cgggattaat agctaaaaat
     4681 tgggatgcaa taaaatctgg cgtttctgag gcgtgggcca atatcagaca atctatcagt
     4741 gataaatgga atgcgatcct ggctgatgtt tccgcgcttc ctgcgaagtt tcaggacacg
     4801 ggcagcgcca ttattgacag cattctcgat ggaattaatg ccaaatggga gacactcaaa
     4861 agcaagcttt cctcagtcac cgattatctg cctgactgga tgactgaaaa taataaaaca
     4921 caagacaaag cacaggtgca ggtggttggt ggcgcagcgg ctgctgctgt tccgtttgcc
     4981 gggatgtatg acagcggtgg gattattccg cgcggtcagt tcggtattgt tggggagaac
     5041 ggccctgaaa ttgtgaacgg ccccgcaaaa gtgaccagta ggcggcgcac tgccgcgttg
     5101 gcttccatcg ttgcaggtgt catgggcgta gcggcagcgc ctgcagaggc tgctccacta
     5161 catccttaca gtctgcctac tgcggcatat aaacaaagcc agcctgcgaa atctgccagc
     5221 gcgccgccag tgatgcactt tgaaactcac gcgccgatca ctatctatgc tcagccaggg
     5281 cagagtgcgc aggatattgc ccgtgaagtt gcccgacagc ttgacgaacg cgagcgcaag
     5341 accagggcta aagcacgcag taatttcagt gatcaagggg gatatgaata atgatgatgg
     5401 tactggggtt atatgtcttc atgctgcgta cagtgccata tcaggagctg cagtatcagc
     5461 gaagctggcg acacgccgcc aacagtcggg tgaaccggcg accatcaacg cagtttcttg
     5521 gcccggataa tgacccgctg acgttatctg gcgtactgct gccggaagtc accggcggca
     5581 ggctgtcatt gctggcactt gagcaaatgg cagagcttgg caaagcatgg cccctgattg
     5641 agggaagtgg gaccatttac ggcatgtttg tgatcgagag cctgagtcag acaaaaacag
     5701 agttttttga aagcggaatg tctcgccgta ttgagtttac gctgaccctg aaaagggttg
     5761 atgagtcgct gtctgatatg ttcggcagtc tcagcgatca gctcagtaac ctgcaggact
     5821 ctgcaacgtc tgcgataggt aatattaaaa atacggttgg agggttgctg cagtgaattt
     5881 tagctctgat ctttttggcc tgaacagcag aagcccggct ttcagtatca ctattgaagg
     5941 taaggacgtg accaccgcgc tggatgcgcg cctgatgagt ctgacgctga ccgataaccg
     6001 gggttttgag gctgaccagc ttgatctgga gctggacgac gccgacgggc agatcgttct
     6061 gccgcgacgt ggtgccgtta ttcaactggc gctggggtgg aagggccagc cgcttttccc
     6121 aaaaggggca tttacggtag atgagattga gcacagcggt gctcctgatc gtctgactat
     6181 ccgtgcccgt agcgctgatt tccgtgaaac cctcaatacc cggcgcgaaa aatcatggca
     6241 tcagacaacg gtgggggagg tggtaaagga aatcgccgcc cggcataacc tcaaagtggc
     6301 gctgggtaaa gacctgacgg ataaggtgct ggatcatatg gaccagacca atgaaagcga
     6361 tgcaagtttt ctgatgaaac tggcgagaca gtatggggcg attgcttccg ttaaggacgg
     6421 gaacctgctg tttatccggc agggacaggg aagaacggcg agcggcaagc cgctgccggt
     6481 tatcactatc acgcgcaaag ccggtgacgg tcatcgtttt accttggctg atcgtggcgc
     6541 gtatacgggc gttattgcca gttggctgca tacacgtgaa ccaaagaaga aagaaacaac
     6601 gcaggtaaag cgccgtcaca agaaagtcgc cacacccaaa gagccggaag caaaacaggg
     6661 tgattatctg gtgggaacgg atgaaaacgt gctggttctt aatcgtacct acgccaaccg
     6721 cggcaacgct gagcgtgcgg caaaaatgca atgggagcgc ctgcaacgtg gtgttgcgtc
     6781 tttctccctg cagctcgcag aggggcgggc agatctctac accgaaatgc cagtaaaggt
     6841 gagcggtttt aagcagccta tcgacgatgc cgaatggacc attacaacgt tgacgcatac
     6901 ggtcagcccg gataatggtt ttactaccag tctggagcta gaagtaaaga ttgatgattt
     6961 agaaatagaa taaataagtt ctcaataata atttcttgtg tatcattatt gagaacttaa
     7021 tggcggcgga gaaactcaaa atgatgaatt gtccaaagtg tggacactca gcgcacacta
     7081 ggagcagctt tcaggttacg gacagcacaa aagagcgtta ctgccagtgc cagaacatta
     7141 actgtggtag cacctttgtc acccatgaaa cggtagtgcg ctttatagtt acgccagcat
     7201 tggtaaataa cgctcctcca catccaacag tgagtgggca agggcacatg aatttttaag
     7261 gtaagttgat ggcattctta ctcaaaaaga caagggagga atgccgcaag aaaccaaaga
     7321 aaatcatggg tttcattaaa cttcattatt gaagaggttt aataaagctg gttctatagg
     7381 tgcgcgcctg ctcgtctttc attgtgccag cttttctaca ctcatcccct ccagcattga
     7441 tttcaaagcc ctgatcgcta gtgacattaa gaagtgtaat tctcttgatc gtgccaggtt
     7501 tccacttgtt catataataa tcattacaga tgccttggaa catcgattca gctgcatcta
     7561 ccagcaaaag tcgtttgtta tatctgatag tcagcccacc atcttctagg ctgtgcgtcc
     7621 tggtatcgta aacagcaatc aggttttgga tagaagatgg gattttgtca gcagatgcgc
     7681 tgaagctggt gatgagcaat aaggctatta gaggtttatt catatctgta gtcctttaat
     7741 cgataaatgc ttgccgccat tttgtcgcca ctaccaaaga aaaaggggct acgttttcac
     7801 gtaacccatt gttttatttg gtggagctgg cgggagttga acccgcgtcc gaaattcctg
     7861 cataccctgt cctctatcct gaagagctgc agatattcgg tgtagtgatc gcattcgtac
     7921 acaaaacccg gagtaaagac tgatgttcgc cctggctgac gtcaacagct tctacgcgag
     7981 ctgtgaaaaa gtatttcgtc ccgatttacg taatacacct gttgtggtgc tcagtaacaa
     8041 cgatggatgt gttatcgcgc gttcaaaaga agcgaagcaa ctgggcatta aaatgggggt
     8101 tccgtggttt caactgaaaa caaccgaatt tcctgtacct gtcgttgcgt tctcgagtaa
     8161 ctacgaactc tacgcgtcga tgtcgaaccg tgttatggcg catctcgaag aactggcacc
     8221 tcgcgttgag cagtattcta tcgacgaaat gtttcttgat gtgcgcaata ttgacagttg
     8281 tatcgatttt gaagacttcg gccggcagtt gcgcgagcat gtacattcag gaaccggact
     8341 gaccatcgga gttgggatgg gaccgaccaa gacactggca aaaagcgcac aatgggcgtc
     8401 taaggaatgg cggcagtttg agggcgtgct tgctctgact tcaggcaatc caaagcgaac
     8461 ggagaaacta ttgtcactgc agccagtaga cgaaatctgg ggggttggtc gccggatctc
     8521 gaagaaactg cacacaatgg ggataacaac tgcactgcag ctggcgcgcg cgaacccaac
     8581 atttatcagg aaaaatttca gtgttgttct cgagagaact gtccgtgaac tgaacgggga
     8641 aagctgtatt tcactggagg aggctccgcc acccaagcag cagattgtct gcagccgatc
     8701 ctttggggag cgcgtcacaa catatgaagc catgcgccag gcagtctgtc agtatgctga
     8761 gcgtgcagct gaaaagctgc gcggcgagcg gcaattctgc agacatgttg ctgtatttgt
     8821 gaagacgtca ccgttcgctg tgaacgaacc gtattacggg aatgtggcca gtgagaaact
     8881 gacgactccc acgcaggata ccagggacat catagccgca gcggtgaaag cactggatcg
     8941 gatctgggtg aaagggcata gatatgcaaa agcgggttgc atgctcaatg atttcacacc
     9001 aaccgggatt tctcagttaa atctttttga tgaagtgcag ccgcacgaac gaagtgagca
     9061 gttgatgaaa gttctcgaca gtatcaacca ttcaggtatg ggaaaagtgt ggtttgccgg
     9121 aagagggata gcccctgagt ggcagatgaa aagagagcta ctctctccag cttataccac
     9181 tcgctgggct gaattacctg ttgcacgatt gcgctgaatc agctcattga gactcagtga
     9241 aaaaggctga atttcatggt tgaaaatcaa tacattgcca tctgaagaac tgctatcgta
     9301 gtgccaataa ccattctttt aatgtgcatg ttaacaaaag aggtttaaat gagaataaac
     9361 gtactattac taaccagtct gttagtagct ggaccggcac tggcaggaga agctcacgtt
     9421 tgtaaatcac agacggtagc gaactctgca gcgaatgccg agttgacgga taacacggta
     9481 tttaaatgcg gcgaaagcat ttccggaact atcccgtcac ttgcccggga gggatggaaa
     9541 attgtgcaac agacagatca ggcagatgtc accgatccat caaaaacata cgcacaattg
     9601 atcatccaga aggattaatg ctgtcgttga taattcatca cactttcgtg cacgctccct
     9661 gacgggaata cccccgtcag ggtaagattt tacgcgggtc cggagacccg ctcagtttta
     9721 acactcgatc ttaaattctt cgttgctggc cgtgatatac agcggtttcc tctcgttcag
     9781 aatgcggtta atcatgcttt tcgtcagatt tatcgtctca ccaaaatcat caccccctac
     9841 ttctgcccgg gcggtatccc accaggcctc atccttttct ggatggcatc ccttcgcata
     9901 agccactttt cggccacgcg gagtgagctc accggtttca gacataatat aaacgccatg
     9961 atccttgacc agtaccacgc cacagtggtt tttacgtgcc tcaagcagta ccggttttaa
    10021 gtcttttgca ctgaatttca gcatgatgtt tctcctgtaa aaaaagggga gaaacatccc
    10081 caccgggaga gtttctcccc ggtgggttta ccgttgattt atgcagccag tcgtggctgc
    10141 tgtggtaccg gttgatcaat caccggctgc tcaaactgct cacgtaccca gctgatggcc
    10201 tggctcatcg cctcaccata atcgctgctg gtcatcctgt tgatgttatc cacctcactg
    10261 tcccaggtga acgactccag caaaatgccg tttttatagt aaacattcac cacaaagcag
    10321 actggagtaa aaagcccgtc cgcgactttg tcgacccagg acacgatgta ttccggattg
    10381 aactccagaa tgtctatctc atcgatatcc tgcggcccca caaataaacg cagtgaaccg
    10441 tactccccgc ggaattcgcg cagctgcctg ggctctgtcg tgcagttcgc cacaaagcat
    10501 ttcagtttct gatagcaatg ctgagtaatg tcctgcaact gctgcgccag ccagctctca
    10561 aaacggtgcc agtatcgtac cgttttgctg aatatcacct gtggaatacg ccggtgtgcc
    10621 ggtaaatcct gctggccggt cacccgcagg tacgtttctt cgtccgcctc cgtcagcgcc
    10681 gcagggtttc ccttcagcag caggtcgcac tgaccactgc tgtgagggtg aacccgggga
    10741 agccagtcag gttgttctgc ctccttcgac agcatatcca gtccggctat ccacagcgtc
    10801 agtacctgcc ggcagcgcgc cagcgtggtt tcatcactgt ccagaccgga cagcatgaca
    10861 tccatcaccg ccatcagttt ttcccggtca aactgtatcc gggtattcac gtagtcggaa
    10921 cggctgccgc gaagctgcca ggtaatatcc tcttcggtta cgtccagaca cagccgctct
    10981 gagaaatgct ggctgatata ttcgtcaata atgctcacgg gaaaatcctc tctggtttat
    11041 taaagggatt ttccccctca ggggaaaatc ccctgagggt atagtggtta atcaggcggc
    11101 cagtttcagt gccggccggg ttaaaggtat ctcaaccagc gacgtccgtt cctggcgtag
    11161 ccagtccagg gcctcgctga caacattctg ccagtcgctg acatggggat gttccacatc
    11221 aatcacgtcg gcgtctcgcc tgaagacgtt cagctccgaa tcgttgcggt atattacccg
    11281 cacttcaaag cgaaccggcg tcagattacc ggccataatt tcctccagat aatcttccag
    11341 cgatgcgtcg tcatacgcgt agagatactg acattcatca atatcccgtc cggacatatg
    11401 cagctcaata cgtccgaaag ccaggttaaa gcaccgtatt ttcctgggct ccacgtgcag
    11461 ccggcgataa agacgcccga gttgcaccag acaacgatct tccacctgat aaagttcacg
    11521 ggctatccac gccataaaac gcgtccagta aggcatcgtc gctgcaagct gttcccgggg
    11581 gaactgctct ccggacatca ggtgacactg ggcggtcagg cgtaagaatg catcatccgg
    11641 cagcgccagc agtgcctgtg ggtcccccgg cagcagacga tcaactcgtc cactgcactc
    11701 cgtaatcgtc cggggcagta tcgacatatc ctcagacact gttgccagcg cgtcgagacc
    11761 acgaatccat agtgtcagaa tacgctctgc ctgacggcat ctttcccgga gctccggatt
    11821 aagcgccacg tcatccagca taaactgcat cacggacaat aaccggtcac ggttcagtac
    11881 catatcggta ttgacgtaat ccgactcccg atcgtccacc tggtaaaaaa cctcctcagc
    11941 gttcacactg aggcccagtg ctttactgag ctgccgttga atatagaaac tggccagcat
    12001 aagtgactcc tgttcagaac aggaattctc cccacaggga gaaccctgtc gggatgaaga
    12061 taaatacgca actaggccgc tttacgcgtc cgatctgcct gccaccggtg atgccaacga
    12121 cccagtacaa acattggtgt tgccatctcc cgtttaatct ccacggtcag gctgttgccg
    12181 gtagccacaa tggccggaat acccatcagg gatagctgga tgtaacacat catcgaggcc
    12241 accgggtcaa tatcgacaca gtacgctacc atctgtttct gcggattaaa tcccgcctcc
    12301 agcatggctt ctgccagcgc aacgaccata cttccggcac cactggcagg atcgctgaca
    12361 gtaataaagt ctcgttcccc gctggaaagt tcaggtatac ggtcactgag tgtcattcgc
    12421 gccatcgcgt acgaaacgct gtaaggcgtg aaatactgtg cgttatgaaa atttcccagt
    12481 ccggatatca tataaattcg ccccaggaaa tctgttggac tgaattccag ccccataaca
    12541 acttctgaca gtaaacgggc catgttgttt gcatcttcag ctgaatagtg ggatacccgc
    12601 ctcatgtagt ccgcttcaaa atcaggatcc cgatgtacag cgttgtacag tgaacaggcc
    12661 gccatatgga cgaaatcact gaatacctgc cagcggcttt catgaggtgc aataccgtta
    12721 aagatactga caaaacgatg tatatgcggg ttctcctttc ccctgcgggc agcccagggc
    12781 agcgccacaa cattgtcatt accatccggg tcatcaggcc cgtcatcatt cgccgcactc
    12841 ttaccttccg acaccgccgg tgccaggagc aaaggtaaac tttcgacctg caccgcttcc
    12901 gctttcctgt ccggtatacc ggatggcaca ggcacgcggt aacaggtcag cagttcggga
    12961 cgaatttcag acaaagtcag tatttcactg tctggtcctg cttcgttgat aaacagcgac
    13021 cgctgaggct ggtcgtagcg ttcccactgg taaatgcggg ccagtgcatt aatcgccatc
    13081 agtggagtga tcccacattc aatatgccgc tcaaccacac tgcgacatcc cagcgtggtg
    13141 tcatcgagag aaaaaccgta atgcgtttca agaatcaatg aggccatctt ctgccacatc
    13201 tccactgtcg tcatcgaggg tcttcgctct ttcagccaca tcatcgcctt tcgcgctgct
    13261 tccgcagccc gaaagagacg ccacgggtcc ccctgtaaat atgtcaccca gggtgccaca
    13321 tccagcctgg atagcatcgc tcccggtaat cccagagcag ccgagagaaa tgcggcgccc
    13381 agttctgcaa ccagggcctc atgaacctca tcggtacgtg tatccactgt taatccgaag
    13441 cgatgtaagc gctgcggatg tccggtagcc tgaaccagca gattcagtat gtcctgccag
    13501 tatgtctcct ctccgacata cgatgccacg ggtggaagct caatccggtc atgcaatgcc
    13561 cggtataccg gcaaaacgtt gtccctgtgg atcacgggaa ccccactgtt ctgaagcagg
    13621 tcgcggatca cattcagtga cggctgaggt cgtggaggca gtggccaccc cggttgcagc
    13681 gtatccggca gaccatcaca ctgttcaggg ttaattacct tgaaaagcga taacgaaggc
    13741 cggtagcgga ccagggtgac tggcttttca ccggatctga cctgaccgcc cagttggcgg
    13801 aggtcatctc cggtcagcca ccttcctgaa cgaagcgaac gctgctgcat ggcctgccac
    13861 aataacagta cgttaatacc ggtaaacggc acgcccgtaa gcgcgtgttc cggtaacccg
    13921 ggaattgtgc cccgccacgg tacctggcct gcagccaggc tactgataag tcggccggag
    13981 ataaaccggc tgatatcatc cggatgtaac gatgtgttca tatgctctcc tgaaaaaaag
    14041 ggagagcgcc cccacaggga gtcactctcc ctacgggata aggttcagta acgcaggatg
    14101 cgtacgtgat tacggtacca gccgaccaac aaatccgagg atacggccag gcaacgtcgc
    14161 cagctcctgt ccgatcagca aaaactgctc aggatgaaag tgaccgtata acaacactga
    14221 tgtcaccacg cccgttaagg tcatccccaa cagcagacgg ttacgccgcc gccggaactg
    14281 cgcctctttt tgctgtacct gcagatgcag gtacagcccc agcgtctgca gctcggcaaa
    14341 gcgggcaaat tcttcccgcc ttaaggcctc gcatgcctcg tcatagcgca gcagctccgt
    14401 cggatggttc ttcttcagaa agctgcgata accgccatcc ctcatcgtgt gataatgtcg
    14461 gtcaaattcc gcctgtaacc actggttgaa acggttacgg gttcttcgaa aaacttccgg
    14521 ttctgctact gtggatgcag gggtttcgtt agtggtcatt acgctcatac agactccttt
    14581 tgagtaaaaa gatctgacgg cgtccccctc acgggtttcc ccgtcagggt aggtggtaaa
    14641 actgattaac gatcgaaagt gagtgtcacc tgaccgtctg aatattcacg tttaatacat
    14701 acgttctgcc acaatggggc atggaggtca ccatcaggcg ggagacagaa atagccaaac
    14761 tccactattc cctgccccga aggtgcctga ctgagtgcct gaaaaccgtg gtatatcaac
    14821 cgctgcagcc gttcgttttc acagtccgga gcctgggggt attttaccag ttgttcccag
    14881 accggctcct cgatagcgac ggccggcggc gtgctgctca gcagcgccat tatatccatc
    14941 atgcggcctc atcattaacc ggggctgttg tcactacgtc agtaaccagc actgacactg
    15001 gagcatttcg ccggttctgc cgccggtgcc ggctgccaag aaaccgcagc aacatctgct
    15061 cagccaccat cacggattcc ctgtcgtcta caaattgtct ctcgctgtaa tacggctccg
    15121 cagcctcttc accgaagtaa agcagctcca cgccgggttt cagcgcatcc ctgagccgga
    15181 gaacaacggc ccgaccgcag aactgaccat catcggccag ctgccagcga ccggtataca
    15241 ccgttcgggg gcgccagtcg gaggcctgca gtctggcctg tcttcgacga tataacaccg
    15301 aaataccgtg atacaccgtc agcccggtcc agcgcatgac gcgccagaga tggtgcaaca
    15361 aaaatacaaa caagcgggtg gttaacatca ttgtgaatct ccttcttctc agaacagacg
    15421 cagcaccagt aacaacattg ccagcatgag ggttcccgcc agcttcagca ggagcatcag
    15481 gccaataagc tttatcagtg ctgcgcggtc gcgggaataa cactcctcat gcaccagatg
    15541 gcgcacgcgg ttttcctgct ccggagtcag tgtgttgccg gttttttcac aaaccgacgg
    15601 aaggtgaatg tgagacatag gatccctgta gaaataaagg aacctgcccc tgacggggct
    15661 gggccccggg gtgtgaaaca aaacaatacg accccgtcaa caacgacgga aaatatgaat
    15721 aatagaatta tcaacccata tcaggcctcc tgcgtaaaat gcgggagccc ttgcgggcat
    15781 ccccgcaagg gtaaaaaagt tgatactatg gcattccccg tctttcaacc gccagctgtt
    15841 cccttatcgg gttgccactg acagacgaaa aacaggaatg gttagccggt aatgttccgg
    15901 ggagcaccac aaaacaacgg cagcgctcag ccagccgccc cagacaggcc tgtagtacag
    15961 acctcaaaaa gttaaaaaca atctcatgct aagcaggatc atacagccag ccatccgctt
    16021 ctgcagcgca tatagcccgg tctgcccggg cttcattgcg ccccagaaga acagcctgtg
    16081 tccaaacggg ttcacacaac attctcccca tatgttcaat cgagccagtc agttcatgtc
    16141 cggctgttgt cagaacgtca atatcttctg attcaagcct ttccataaat tctccgaaag
    16201 ccataccaca gttaaatacc gcacattcaa actccggttc ctcctgcctg tcatcataaa
    16261 gcggatataa accggcgttc agagaagcct ggatactcag caaatcgccc tcaatcagcg
    16321 aaagccagat caaaacgtca gtgcggtttt tcagttgata aacgttcata aatcctcctg
    16381 tcagaacagc aacagaggga tttaccccct acggggaaaa atcccctgtt gggtggtaac
    16441 gttaatgcag tggaaattcg ttttctaatc ggtcagttcc caggcatagc gaagatgtgc
    16501 aagttcaagt gcctgggagt acgcggtatt catggcacag tgaaatgaat caaacttgcc
    16561 acaatccacc acctgttcat agcgtggatt catccagccg gaacgtttgt tgacgactgc
    16621 gtgaaaatgg tcgttatcat ccagccagac ctctgcctga aaacgcagat aaccggtgtg
    16681 attggcgatc cattcacttt tgccgtgacg tatacgtgga agtgccttac gcagaatact
    16741 gaccagagaa gtcagaaaga tgttcatagt tttctccaga agtaaaacgg agaaaaccat
    16801 caccgtatcg gggaggcttt ccccgatggg caggatgtaa gatttgtggt ttaaacgtct
    16861 caaagcgagc gatacgaacg agcgctcctt caaagaagac actggaccaa aatgatcaac
    16921 agtctgtacc cggaataccg gtataaaacc tgccacagtg ggaagatttc ccaccggaaa
    16981 tgctgaaaga cgagtatcga agtgtgaatg ttgaggatat cttcatcgca aaaaatgcga
    17041 cagccatttc caaagattaa agggctgtac cacccgaagg cgtcacctct caggctacgg
    17101 tgacattggt gtgcaatcac ccgaaggcgt tcctctcaga ttgccggaac attggttatg
    17161 tgatcaccca aaggcgttcc tctcagatca ctggaacatt ggtggttgcc taaggcaacg
    17221 ttttaagcgc tatcatatta accagagcga gaatgaaaat tcaagaccgt aactgaagtt
    17281 ttttaacgtg ctaaagacag gtacatgaga agtctgcacg agataaagct ggaaatttca
    17341 ggtactaaaa aacactccac tgaaagtcaa tctttcatac tgacgcaaat aatcactttc
    17401 tgtgtatctg cttttatgaa ttaatgtaaa ccctcattag aatcagcaaa tccctaaaaa
    17461 acattccctg cctcatcgac tgaacatgag ttactcatct tcagtaccat ctctgaaata
    17521 aacctgtttt acatatctcc ctcttccgtc tccatgacct aaatccattg acacctgagc
    17581 atatatttcc ttaccagaaa aaccattctt ctcataatat tcccgagctt cctgtgaaaa
    17641 atgataacgc atactgtgag gtgctttttc acctgtcaga cccgcacgtc tgacatgata
    17701 acggtaggta tcaatcgcct tacgaatatc aggacgatca atcaatttac cgttattttc
    17761 cttcattact ttttcagcat aatttattgc atgccttaaa gcgtccttat caacaatcag
    17821 cgtatttcgt cctcttcctc ctttcgtacc aaaaattaca cgaactgaat gttcccctga
    17881 ctcaagagca cgtttccatg tcatcacgga tttacaggac tccactgcct ctttagttct
    17941 taaacccagc gtataagaaa gtaacattgt tgctgcaacc ccccggttgc ttttctcaac
    18001 ctccttaaat gccttttgaa attcttccgg gcttaacggt aattttgttc ccgacctgct
    18061 acttttttct aatccaagag ccttattact caggagcgga ttattcgggt ctgccagctt
    18121 ataacgtccc gccttattca aaacgccacg aatagcagcc cgctcattct gaattgtccg
    18181 cacggaaatc ccctgtgatt ttctgaactg gagatatccg gtgacatgac gtgttttaat
    18241 actgtcggta tgacgtagct taataccgtt atcacgaagg tagttcagaa agtatttcgc
    18301 gatacgcatg ctgtctgcag ccgtcgcgta tgccctgccg gcatcccggg ctaaggtcac
    18361 aaaatcgcga cggaatttct ccacttttga acgagctgtt ttccctgcca tattgccccc
    18421 tgtatgacac tggtgaaaaa agacacacta atccctcagc gcatcccatc agtcagaaca
    18481 cttgtcgata gttctcactc atgaaatgaa ctgtcataac cagctggaaa tattagtttt
    18541 tcgtcatcac agacgttccc tgcgtgtcgg tgcgttcgtc ttcctgactc gtctgatatt
    18601 gtgtagcagg gtagcgctat gttgagtttt tgcaggagtt caaccagtac gcagtacggc
    18661 gaatttaact ccccgtcagt aattactgac gcctcaatat catgacgata aaacctccat
    18721 taatcattac gttaagcttc acagatgaaa ccttaacaac gggttaaaca cgggccctga
    18781 gcggccgtcc gtggaaaacg gacgcgacgg gcgttgtaga aaacgttttt tcagcgcatt
    18841 cctcaaactg gtttcacgaa cgaatgcact ttttaaactg ttcggaagat caggaaatac
    18901 gtgctgaaga tgttttacgc cttgcggcgt cacttggttc tcgttttact cgaacgcaag
    18961 tgacgccgcg tatactcaaa ctgtccaatg catcgtccgg aagatgcccc aaatgttgcg
    19021 acgttcgtcg cgccaaatgg ctggcatacc cgtacatgca aaggttgtct gagcacggag
    19081 gcttaagaag tgagtactaa aagatacggt ataaaaccgt agaaagaaga agcgatcgtc
    19141 cactgttcgt gaagacaggt caaaaatctg ataccgaaaa acggtactta catgtagtaa
    19201 aaatatcttc gtcgcagaag tacacgacag ccgtttccaa agattaaagg gctgtaccac
    19261 ccgaaggcgc cacctctcag gctacggtga cattggtatg caatcacccg aaggcgcccc
    19321 tctcagatca ccggggcatt ggtgggtgca gctaatgcac cattacaacg ttcgtatagt
    19381 agatcattga tgccacgttg atcaatacaa ctcccccctg cttaaaaggc taaatatcat
    19441 attccgcttc atcaaaggca agcctgcggg ttacgacgcc aatattaatt taacgcatat
    19501 atctgaagaa gacttctttg atagtctgat cgtatcgctt cagtcgttga caggatggta
    19561 gtgttggaaa tcttttttta acccactgaa aaatatcttc tgattatttt tcacacacaa
    19621 atctctatgg tccgttccat acagatccgg ttttgtatgg gtaaaaaagg ttaattatga
    19681 aagtaacatg gactgtcact cctgtggggt atcagcacat cgcaaaacgc tgtccgtcat
    19741 gcaatgtaaa aagagacttc acgccgtcag gtgcattcag gattaattca caaaagaaaa
    19801 tactggacgt atggagtatc tataaatgta ctcactgcga ttacacctgg aatatagcgc
    19861 tgtattcccg ccttcctgta agcaaaataa atcaggaact tcatcaccgg ctgatgacaa
    19921 acgatgaatc cacaatcagg cattttgcct atgacactgc tgttctgaag caaaacaatg
    19981 caaaactatc aggtcaactt gatttccgta ttcaggagcg ctgtctgacc agtataacga
    20041 ggcaatatca gatatgtgtc cgaatcaggt taacccgctc tttccaggta agcctgctgt
    20101 ccataatgaa aatacaactt atgctgagtt cggcagatat caggaggcga atagactccg
    20161 ggcagataac tggcgttacg gcaaaaatgc ttaaatcgag aaagttaagg cagacttaat
    20221 attgtcttga gataacggag gaaacattct atgccagacg cagaattaag ttgatacagg
    20281 cttaata
//
LOCUS       DAJVBX010000070        20052 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.070, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000070 DAJVBX010000000
VERSION     DAJVBX010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 20052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20052
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.070"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..213)
                     /locus_tag="OPV72_002165"
     CDS             complement(<1..213)
                     /locus_tag="OPV72_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914455.1"
                     /translation="MKLIIILLLALFPLCSSASNHYALVFENNTILLVLNLKCSPCDL
                     NCANIQYQLFNKETESVISGAAKPVTT"
     gene            complement(437..512)
                     /locus_tag="OPV72_002166"
     tRNA            complement(437..512)
                     /locus_tag="OPV72_002166"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(477..479),aa:Thr,seq:cgt)
     gene            complement(628..1878)
                     /gene="proA"
                     /locus_tag="OPV72_002167"
     CDS             complement(628..1878)
                     /gene="proA"
                     /locus_tag="OPV72_002167"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HCR9914456.1"
                     /translation="MLEQMGIAAKAASYKLALLSSCEKNRVLEKIADELEAQMESILS
                     ANVQDVEQARANGLSEAMLDRLALTPARLKAIADDVRQVCNLADPAGQVIDGGLLDSG
                     LRLERRRVPLGVVGVIYEARPNVTVDVASLCLKTGNAVILRGGKETHRTNAATVLVIQ
                     KALKACDLPEAAVQAIDNPDRSLVSEMLRMDKYIDMLIPRGGAGLHKLCREQSTIPVI
                     TGGIGVCHIFVDSSADIAPALKIIVNAKTQRPSTCNTVETLLVHQDIAERFLPALSKQ
                     MAESGVTLHGDETVMQALHGPAKLVALKPEELDNEFLSLDLNVVVVENMDGAIAHIRE
                     HGTQHSDAILTCDMHNAARFVNEVDSAAVYVNASTRFTDGGQFGLGAEVAVSTQKLHA
                     RGPMGLEALTTYKWIGFGDGTIRA"
     gene            complement(1890..2993)
                     /gene="proB"
                     /locus_tag="OPV72_002168"
     CDS             complement(1890..2993)
                     /gene="proB"
                     /locus_tag="OPV72_002168"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HCR9914457.1"
                     /translation="MSDSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHR
                     IVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHIGQML
                     LTRADMEDRERFLNARDTLRALLDNHIVPVINENDAVATAEIKVGDNDNLSALAAILA
                     GADKLLLLTDQQGLFTADPRSNPQAELIKDVYGVDDALRSIAGDSVSGLGTGGMSTKL
                     QAADVACRAGIDTIIASGSKPGVIGDVMEGISVGTRFHAQASPLENRKRWIFGAPPAG
                     EITVDEGATAAMLERGSSLLPKGIKSVTGNFSRGEVIRICNLQGRDIAHGVSRYNSDA
                     LRRIAGHHSQQIDAILGYEYGPVAVHRDDMITR"
     gene            3276..4328
                     /gene="phoE"
                     /locus_tag="OPV72_002169"
     CDS             3276..4328
                     /gene="phoE"
                     /locus_tag="OPV72_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoporin PhoE"
                     /protein_id="HCR9914458.1"
                     /translation="MNKSTLAIVVSIIASASVHAAEVYNKNGNKLDVYGKVKAMHYMS
                     DYDSKDGDQSYVRFGFKGETQINDQLTGYGRWEAEFAGNKAESDSSQQKTRLAFAGLK
                     LKDIGSFDYGRNLGALYDVEAWTDMFPEFGGDSSAQTDNFMTKRASGLATYRNTDFFG
                     IVDGLDLTLQYQGKNEDRDVKKQNGDGFGTSVSYDFGGSDFAVSGAYTLSDRTREQNL
                     QRRGTGDKAEAWATGVKYDANDIYIATFYSETRNMTPVSGGFANKTQNFEAVIQYQFD
                     FGLRPSLGYVLSKGKDIEGVGSEDLVNYIDVGAIYYFNKNMSAFVDYKINQLDSDNTL
                     GINDDDIVAIGLTYQF"
     gene            complement(4379..4780)
                     /gene="crl"
                     /locus_tag="OPV72_002170"
     CDS             complement(4379..4780)
                     /gene="crl"
                     /locus_tag="OPV72_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-binding protein Crl"
                     /protein_id="HCR9914459.1"
                     /translation="MTLPSGHPKSRLIKKFTALGPYIREGQCEDNRFFFDCLAVCVNV
                     KPAPEKREFWGWWMELEAQEKRFTYRYQFGLFDKEGNWTVVPINETEVVERLEYTLRE
                     FHEKLRDLLISMELALEPSDDFNDEPVKLSA"
     gene            complement(4838..6082)
                     /gene="frsA"
                     /locus_tag="OPV72_002171"
     CDS             complement(4838..6082)
                     /gene="frsA"
                     /locus_tag="OPV72_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase FrsA"
                     /protein_id="HCR9914460.1"
                     /translation="MTQANLSETLFKPRFKHTETSTLVRRFNRGSQPPMQSALDGKNV
                     PHWYRMINRLMWIWRGVDPREILDVQARIVMSDAERTDDDLYDTVIGYRGGNWIYEWA
                     KQAMDWQQKACQEQDAMRSGRYWLHASTLYNIAAYPHLKGDELAEQAQALANRAYEEA
                     AQRLPGSLREMEFAVPGGSPVTAFLHMPKGDGPFPTVLMCGGLDAMQIDYYTLYERYF
                     APRGIAMLTLDMPSVGFSSKWKLTQDSSLLHQHVLKALPNVPWVDHTRVAAFGFRFGA
                     NVAVRLAYLEAPRLKAVACLGPVVHALLSDPQRQSTVPEMYLDVLASRLGMHDASDEA
                     LRVELNRYSLKVQGLLGRRCPTPMLSGFWKNDPFSPEEESRLITTSSSDGKLIEIPFN
                     PVYRNFDHALQEITDWINHRLC"
     gene            complement(6171..6629)
                     /gene="gpt"
                     /locus_tag="OPV72_002172"
     CDS             complement(6171..6629)
                     /gene="gpt"
                     /locus_tag="OPV72_002172"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HCR9914461.1"
                     /translation="MSEKYVVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGA
                     LLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIRE
                     MYPKAHFVTIFAKPAGRPLVDDYVIDIPQNTWIEQPWDMGVVFVPPISGR"
     gene            6878..8335
                     /gene="pepD"
                     /locus_tag="OPV72_002173"
     CDS             6878..8335
                     /gene="pepD"
                     /locus_tag="OPV72_002173"
                     /EC_number="3.4.13.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosol nonspecific dipeptidase"
                     /protein_id="HCR9914462.1"
                     /translation="MSELSQLSPQPLWDIFAKICSIPHPSYHEEQLAEHIVSWAKEKG
                     LYVDRDQVGNILIRKPATAGMENRKPVVLQAHLDMVPQKNSDTVHDFTTDPIRPYIDG
                     EWVKARGTTLGADNGIGMASALAVLADDNVVHGPLEVLLTMTEEAGMDGAFGLQSGWL
                     QADILINTDSEEEGEIYMGCAGGIDFTSNLPLTREAVPAGFACFKLTLKGLKGGHSGG
                     EIHLGLGNANKLLARFLAGHAEELDLRLIDFNGGTLRNAIPREAFATLAVATDNVGAL
                     KTLVNAYQDILKNELAEKEKNLTLQLNEVASDKAALTAPSRDTFVRLLNATPNGVIRN
                     SDVAKGVVETSLNVGVVTMSDANVEIHCLIRSLIDSGKDYVVSMLDSLGKLAGAKTEA
                     KGSYPGWQPDANSPVMHLVRETYQRLFNKTPNIQIIHAGLECGLFKKPYPDMDMVSIG
                     PTITGPHSPDEQVHIESVGHYWTLLTELLKAIPAK"
     gene            complement(8490..9104)
                     /locus_tag="OPV72_002174"
     CDS             complement(8490..9104)
                     /locus_tag="OPV72_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor H"
                     /protein_id="HCR9914463.1"
                     /translation="MILLQLSSAQGPDECCLAVKKALDCLTKEAAREKVSLTRLETEP
                     GRLPDTLRSALVSLDGEKAMAFSERWCGTLLWICTSPYRPHHGRKNWYVGIGRFSADE
                     HIQSDEIRFETLRSSGPGGQHVNKTDSAVRATHLASGISVKVQSERSQHANKRLARLL
                     IAWRLEQQRQNECAALKSERRLFHHQIERGNPLRIFKGMAFTPQ"
     gene            complement(9101..10240)
                     /locus_tag="OPV72_002175"
     CDS             complement(9101..10240)
                     /locus_tag="OPV72_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006895405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA ligase RtcB family protein"
                     /protein_id="HCR9914464.1"
                     /translation="MGNYIRPLSDVVFSIASDNLWIEDSAIQQLYTTAKLTGMKRVIG
                     MPDLHPGRGYPIGAAFFSRGRFYPALVGNDIGCGMALWQTDILGRKYNADKLEKRLAS
                     LPDVADAQWLEENVPAVMQHHSWRSALGSIGGGNHFAELQQVDRIVDADSFALSGLQK
                     AQLLLLVHSGSRGLGQAILRRHVEAFSHNGLPEDSDDARHYLAEHDDALAFARSNRAL
                     IARRILQQLRAEGEPRLDVAHNFVEPCTVAGEAGWLHRKGATPDGQGLVIIPGSRGDY
                     SWLVKPVVSEESLFSLAHGAGRKWMRTECKDRLSAKFTPRQLCRTGMGSRVICRDRQL
                     IYEEAPQAYKSIDSVVDCLADAGLITPVACLRPVLTLKTSGEKSA"
     gene            complement(10459..11514)
                     /gene="dinB"
                     /locus_tag="OPV72_002176"
     CDS             complement(10459..11514)
                     /gene="dinB"
                     /locus_tag="OPV72_002176"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HCR9914465.1"
                     /translation="MRKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTA
                     NYPARQFGVRSAMPTAMALKLCPHLTLLPGRFDAYKEASRHVRDIFSRYTSLIEPLSL
                     DEAWLDVTDSPHCYGSATLIAREIRQTIFNELQLTASAGVAPVKFLAKIASDLNKPNG
                     QYVITPADVPDFLKTLPLAKIPGVGKVSAAKLENMGLRTCGDIQQCDLAMLLKRFGKF
                     GRVLWERSQGIDERDVNSERLRKSVGVERTLAEDIHEWSDCEAIIEHLYPELERRLAI
                     VKPDLLIARQGVKLKFNDFQQTTQEHVWPQLNKEDLITTARKTWDERRGERGVRLVGL
                     HVTLLDPQLERQLVLGL"
     gene            11764..12504
                     /locus_tag="OPV72_002177"
     CDS             11764..12504
                     /locus_tag="OPV72_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein L,D-transpeptidase"
                     /protein_id="HCR9914466.1"
                     /translation="MRKIAFFLAMLLMPCVSFAGLLSSSSPVTPVSKEYKQQLMGSPV
                     YIQIFKEERTLDLYVKMGEQYQLLDSYKICNYSGGLGPKRRQGDFKSPEGFYSVQRNQ
                     LKPDSRFYKAINIGFPNAYDRAHGYDGKYLMIHGACVSVGCYAMTDSGIDEIFQFVTA
                     ALVFGQPSVQVSIYPFRMTDANMQRHKYSYYKDFWAQLKPGYDYFEQTHKPPTVSIVD
                     GRYVVSKPLSHEVVQPQLASNYTLSEAK"
     gene            complement(12475..13242)
                     /locus_tag="OPV72_002178"
     CDS             complement(12475..13242)
                     /locus_tag="OPV72_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II glutamine amidotransferase"
                     /protein_id="HCR9914467.1"
                     /translation="MCELLGMSANVPMDICFSFTGLVQRGGGTGPHKDGWGITFYEGK
                     GCRTFKDPQPSYHSPIAKLVQNYPIKSCSVIAHIRQANRGEVALENTHPFTRELWGRN
                     WTYAHNGQLNGYKSLETGNFRPVGETDSEKAFCWLLHKLTQRYPRTPGNMTAVFKYIA
                     TLATVLREKGVFNMLLSDGRYVMAFCSTHLHWITRRAPFGVATLVDQDMEIDFSSQTT
                     PNDVVTVIATQPLTGNETWQKIMPGEWALFCLGERII"
     gene            complement(13406..13984)
                     /gene="lpcA"
                     /locus_tag="OPV72_002179"
     CDS             complement(13406..13984)
                     /gene="lpcA"
                     /locus_tag="OPV72_002179"
                     /EC_number="5.3.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-sedoheptulose 7-phosphate isomerase"
                     /protein_id="HCR9914468.1"
                     /translation="MYQDLIRNELNEAAETLANFLKDDANIHAIQRAAVLLADSFKAG
                     GKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDVSHISCVSNDFGYDYIFS
                     RYVEAVGREGDVLLGISTSGNSGNVIKAIAAAREKGMKVITLTGKDGGKMAGTADIEI
                     RVPHFGYADRIQEIHIKVIHILIQLIEKEMVK"
     gene            14224..16668
                     /gene="fadE"
                     /locus_tag="OPV72_002180"
     CDS             14224..16668
                     /gene="fadE"
                     /locus_tag="OPV72_002180"
                     /EC_number="1.3.8.7"
                     /EC_number="1.3.8.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase FadE"
                     /protein_id="HCR9914469.1"
                     /translation="MMILSIIATVVLLGALFYHRVSLFLSSLILLAWTAALGVAGLWS
                     IWLLVPLAIILVPFNLTPMRKSMISAPVFRGFRKVMPPMSRTEKEAIDAGTTWWEGDL
                     FQGKPDWKKLHNYPQPQLTAEEQAFLDGPVEEACRMANDFQITHELADLPPELWAYLK
                     EHRFFAMIIKKEYGGLEFSAYVQSRVLQKLSGVSGILAITVGVPNSLGPGELLQHYGT
                     EEQKNHYLPRLARGQEIPCFALTSPEAGSDAGAIPDTGVVCMGEWQGQQVLGMRLTWN
                     KRYITLAPIATVLGLAFKLSDPDRLLGGEEELGITCALIPTSTPGVEIGRRHFPLNVP
                     FQNGPTRGNDIFVPIDYIIGGPKMAGQGWRMLVECLSVGRGITLPSNSTGGVKSVALA
                     TGAYAHIRRQFKISIGKMEGIEEPLARIAGNAYVMDAAASLITYGIMLGEKPAVLSAI
                     VKYHCTHRGQQSIIDAMDITGGKGIMLGESNFLARAYQGAPIAITVEGANILTRSMMI
                     FGQGAIRCHPYVLEEMAAAQNNDVNAFDKLLFKHIGHVGSNTVRSFWLGLTRGLTSHT
                     PTGDATKRYYQHLNRLSANLALLSDVSMAVLGGSLKRRERISTRLGDVLSQLYLASAV
                     LKRYDDEGRHEADLPLVHWGVQDALYRAEQAMDDLLQNFPNRVVAGLLTAMIFPTGRH
                     YLAPSDKLDHAVAKILQVPNATRSRIGRGQYLTPAEHNPVGLLEEALRDVIAADPIHQ
                     RICKELGKNLPFTRLDELARNALAKGLIDKDEAAILAKAEESRLRSINVDDFEPEALA
                     TKPVKLPEKVRKVEAA"
     gene            16776..17543
                     /locus_tag="OPV72_002181"
     CDS             16776..17543
                     /locus_tag="OPV72_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HCR9914470.1"
                     /translation="MSGLKITLLQQPLVWMDGLANLRHFDRQLELVSGRDVIVLPEMF
                     TTGFAMEAANNSLSQDSVITWMQAKARQTDALIAGSAALQTERGAVNRFLLVEPEGKV
                     HLYDKRHLFRMADEHQHYAAGDKRIIVQWRGWRILPLICYDLRFPIWSRNRNDYDLAL
                     YVANWPAPRSLHWQTLLTARAIENQAYVAGCNRVGTDGNGLHYRGDSRIINPQGDIIA
                     TAEPHQATRIDADLSLVALQDYREKFPAWRDADPFTL"
     gene            17853..18260
                     /locus_tag="OPV72_002182"
     CDS             17853..18260
                     /locus_tag="OPV72_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spy/CpxP family protein refolding chaperone"
                     /protein_id="HCR9914471.1"
                     /translation="MKNFVRTTLLAATLAGVSFGAFATAVPNPPLPAQDPIVQHLKLT
                     NDQITRIKKLHQQLETDVSQISMKGIKDGALIEVIKSGKWDDAAVKQQLAAFSNIEQQ
                     ARYYRVKYYFDLSKVLTPEQRQQVQQDLAQALE"
     gene            18585..19304
                     /gene="pagN"
                     /locus_tag="OPV72_002183"
     CDS             18585..19304
                     /gene="pagN"
                     /locus_tag="OPV72_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin/invasin protein PagN"
                     /protein_id="HCR9914472.1"
                     /translation="MKNFFAVCIIPLVVTWSATASAKEGIYITGKAGTSVVNVYGINS
                     TFSQEEIVNGHATLPDRTKGVFGGGVAIGYDFYDPFQLPVRLELDTTFRGETDAKGGQ
                     DIIAFGQPVHINVKNQVRMTTYIVNGYYDFHNSTAFTPYISAGVGLAHVKLSNNTIPV
                     GFGINETLSASKNNFAWGAGIGAKYAVTDNIMIDASYKYINAGKVSISKNHYAGDEHT
                     AYDADTKAASNDFMLGITYAF"
     gene            complement(19308..19496)
                     /locus_tag="OPV72_002184"
                     /pseudo
     CDS             complement(19308..19496)
                     /locus_tag="OPV72_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459303.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            19532..19665
                     /locus_tag="OPV72_002185"
                     /pseudo
     CDS             19532..19665
                     /locus_tag="OPV72_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001458895.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         4989 a         5323 c         4949 g         4791 t
ORIGIN      
        1 cgttgtcaca ggcttggcag cccctgaaat aacagactcc gtctctttat tgaaaagctg
       61 gtattgaata tttgcgcagt ttaaatcaca gggggaacat ttaagattta aaacaagcag
      121 tatcgtgtta ttttcaaaaa caagggcata atgattgctg gcagatgaac ataacgggaa
      181 taacgcgaga agaagaatta ttatcaattt catattatta tatagactcc gtcaaagaaa
      241 actttcattt cacttgttct tctgttaact caccctttca tttcacgccc ctgagaatag
      301 cgaaaggcat accatgcaga atgaatgctt tccgaactga cgtcctcaca gacatccata
      361 ccatgccaaa caagtacgcg agaaagaaaa tgagaagatt gttatgaaag aaaagtttgt
      421 aaccgcttga ttgagatggt gccgataata ggagtcgaac ctacgacctt cgcattacga
      481 atgcgctgct ctaccaactg agctatatcg gccctgagaa gggtgtgttc acgcgggtga
      541 atcacggggt agaaggttaa aactaaccgg gcggtgcgtc aatagccttg ctactcaacc
      601 ggctattttt gcaccgctcg tcattaatta cgcacgaatc gtaccatcgc caaagcctat
      661 ccacttatag gtggtaagcg cttcaagccc catcggaccg cgggcatgta atttctgcgt
      721 gctgaccgcc acttctgcgc caagcccaaa ctgcccgcca tcggtaaaac gggtagaggc
      781 gttgacataa accgcagcgg aatctacttc gttcacgaaa cgcgcagcat tatgcatatc
      841 gcacgttaaa atcgcatcgg agtgctgagt gccatgttcg cgaatgtggg cgatagcgcc
      901 atccatattt tcgaccacca caacgttcag atccagagac agaaactcgt tatccagctc
      961 ttccggtttc agcgccacca gtttggcagg gccatgcagt gcctgcatga cggtttcatc
     1021 cccatgcaac gttacgccac tctccgccat ctgcttgctc agcgcaggca aaaagcgttc
     1081 tgcgatgtcc tgatgcacca gcaaggtttc caccgtgtta caggtgctcg ggcgctgggt
     1141 tttagcgttg acgataatct tcagcgctgg ggcgatgtct gcgctgctat cgacaaaaat
     1201 atggcacacg ccaatcccgc cggtaatcac cggaatggtg gattgctcgc ggcagagttt
     1261 atgcaagcct gcgccgccgc gcgggatcag catatcgatg tacttatcca tacgcagcat
     1321 ttcactgacc agcgaacgat ccggattatc aatcgcctga accgccgctt ccggtaaatc
     1381 gcaagctttc agcgccttct gaatgacaag aacggttgcg gcattcgtgc gatgcgtctc
     1441 tttcccaccg cgtagaatca ccgcattacc ggttttcaga cacaaagaag ccacatcaac
     1501 ggtaacattc ggacgcgcct catagataac gccaaccacg cccaacggca cgcggcggcg
     1561 ctccagacgc aggccgctgt ccagcagacc gccgtcgatc acctgcccgg ccgggtcggc
     1621 gagattacag acctggcgca catcgtcagc aatcgctttc agacgcgcag gggtcagcgc
     1681 caggcggtcc agcatcgctt cgctcaggcc attggctcgc gcctgctcaa catcttgtac
     1741 gttcgcgctg aggatacttt ccatttgcgc ttccagttca tcggctattt tttccagcac
     1801 gcgatttttt tcgcagctgg agagcagcgc cagcttatac gacgccgctt tagcagcaat
     1861 gcccatttgt tccagcatat gcctgttcct tatcgagtaa tcatgtcatc acgatgaaca
     1921 gcgaccgggc catattcata gcccagaatc gcatcgattt gttgagagtg gtgaccggct
     1981 atccgccgca gagcatcact gttataacgg ctgacgccat gagcgatatc acgcccttgc
     2041 aggttacaaa ttctgatgac ctccccccgc gaaaaattgc ccgtcacgct tttgatgcct
     2101 tttggcagaa gtgaactgcc acgttccagc attgccgcgg tcgcgccttc atcaaccgta
     2161 atttcgcctg ccggcggcgc gccgaagatc caacgtttgc ggttctccag cggcgaggct
     2221 tgcgcatgaa aacgggtgcc gacggaaatc ccctccatca catcgccgat cacgcccggt
     2281 ttactgcctg aggcaataat cgtatcaata cccgcgcgac aggccacgtc tgccgcctga
     2341 agcttagtgc tcataccacc ggttcccagc ccggaaacgc tgtctcccgc gatagagcgc
     2401 agcgcatcgt caacgccata cacatctttg ataagctccg cctgcggatt gctacgcgga
     2461 tcggcggtaa ataatccttg ctgatcggtc agcagcagca gtttatccgc gcctgccagg
     2521 atcgccgcca gcgcggagag gttatcgttg tcgcccactt taatttccgc tgtcgcaacg
     2581 gcatcatttt cattgataac cggcacaata tggttatcca gtaacgcacg cagcgtatcg
     2641 cgggcgttca gaaagcgctc tctgtcttcc atatccgcac gcgtcaacag catctgcccg
     2701 atatggatac cgtaaattga aaacaactgc tcccacagtt gaatcagacg gctttgccct
     2761 accgccgcca gaagctgttt agaggcaatt gttgccggca gttccgggta gccgagatgt
     2821 tcacgtccgg cggcaatcgc gccagaggta acgataacaa tacgatgtcc cgcggcgtgt
     2881 agctgcgcgc actggcggac aagttctacg atatgggcac ggttcaggcg gcgcgatccg
     2941 cctgttagca cgctggtgcc gagttttacg accagcgtct ggctgtcact catgattctc
     3001 tgccgttcaa aataagaaat aaagaccaaa tgaacgtttt agcaggactg gctccggttg
     3061 ccaacaacct gtacgcgtag cgtgaaattt tgttgcgcag gatcagcaag cgtagcggcg
     3121 gaatttgacc attttattac cgcaacaatt aaatatattt ttttaaaaaa actctcactt
     3181 tgtcataaat ctttcattac cgaacgttaa aaaccttcct gttttttacc gggtctcccg
     3241 acaaatcata gcgcgtaatt aaaacaggaa tggaaatgaa taagagcact ctggcaatag
     3301 tggtgagtat catcgcatca gcatctgttc acgccgccga ggtttacaat aaaaacggta
     3361 ataagcttga tgtgtatgga aaagttaaag ccatgcacta tatgagcgat tatgacagca
     3421 aagatggcga tcaaagctac gttcgttttg gttttaaagg cgaaacgcaa attaacgatc
     3481 aattgaccgg ctacgggcgc tgggaagctg agtttgccgg taataaagcc gaaagtgatt
     3541 cgtcccagca aaaaacccgc ctggcctttg ctggtctgaa attaaaagat atcggttctt
     3601 ttgactatgg acgtaacctg ggcgcgctgt acgatgttga ggcctggacg gatatgtttc
     3661 ccgaattcgg cggcgactct tccgcccaga ccgataattt tatgactaaa cgcgccagcg
     3721 ggctggcgac ttaccgcaat accgatttct tcggcatcgt tgatggactg gatcttacct
     3781 tacagtatca ggggaaaaac gaagatcgcg atgtgaaaaa gcaaaacggc gacggcttcg
     3841 gcacttccgt gagctatgat ttcggcggca gtgattttgc cgtcagcggc gcttatactc
     3901 tctccgatcg caccagggag caaaatctgc agcgccgcgg tacgggcgat aaagccgaag
     3961 cctgggctac gggtgttaag tatgacgcga atgatattta tattgcgact ttctattcag
     4021 aaacccgcaa catgacgcca gtttccggcg gatttgccaa taaaactcaa aacttcgaag
     4081 cggttatcca gtatcagttt gactttggtc tgcgtccgtc attaggctat gtgctgtcaa
     4141 aaggcaaaga tattgagggc gtcggcagtg aggatttggt gaattacatt gacgttggcg
     4201 caatctatta tttcaacaaa aatatgtccg cgtttgtaga ttacaaaatc aatcagcttg
     4261 atagcgataa cacgttaggc attaatgacg atgatattgt ggcaataggg ttgacctacc
     4321 agttctgata agtcgcattg tgcctgatgg cgctacgcca tcaggcatgg cagcagggtt
     4381 atgccgacag ttttaccggc tcgtcgttga aatcgtcaga cggctccagc gccagctcca
     4441 tagaaatcag caggtcgcgt agcttttcat gaaactcgcg tagcgtgtat tccagtcgct
     4501 ccaccacttc ggtttcgtta atcggcacta cggtccagtt gccctcttta tcaaacaaac
     4561 caaactgata acgataagtg aagcgtttct cttgtgcttc cagctccatc caccagcccc
     4621 aaaattcacg cttctctggc gcgggcttca cgttgacgca aactgccagg caatcgaaaa
     4681 aaaaacgatt gtcttcgcac tgcccttccc ggatataggg gccaagcgcg gtaaatttct
     4741 tgatcaatct acttttcggg tgtccactcg gtaacgttat tgcgatctcc tttaatgaag
     4801 caactgtttt accaaatcaa tagaatttat caatctatta acacaatcta tgattaatcc
     4861 agtcggtaat ttcttgcagc gcgtggtcaa aattgcggta caccgggtta aaagggatct
     4921 ctatcagctt accgtctgaa gatgatgttg taattaagcg agactcttct tccgggctga
     4981 aaggatcgtt tttccagaag ccggaaagca ttggcgtagg acaacgtctg cccagtagcc
     5041 cctgtacttt caacgaatag cggttgagct ccacacgcag cgcctcatcc gaagcatcat
     5101 gcatacccag acggctggcc agcacatcca gatacatctc cggcactgtg ctctgtcgtt
     5161 gcggatcgct aagtagcgca tggaccaccg gccccaggca agccaccgct ttcaaacgcg
     5221 gcgcttccag ataggccaga cgcaccgcaa cgttggcgcc aaaacggaaa ccaaacgccg
     5281 caacacgggt atgatccacc caggggacat taggaagcgc ttttaacaca tgctggtgga
     5341 gcaagctgga atcctgggtt aatttccact ttgatgaaaa tccaaccgaa ggcatatcaa
     5401 gcgttaacat cgcgataccg cgcggcgcga aatagcgttc atacagggtg taatagtcga
     5461 tttgcatggc gtccaggccg ccgcacatga gcaccgtcgg aaacggacca tcccctttcg
     5521 gcatatgtaa aaacgcggtg acaggcgaac cgccaggaac ggcaaattcc atttcacgta
     5581 acgagcctgg caaccgctgc gcggcctctt cataggcgcg attcgccagc gcctgcgcct
     5641 gctccgccag ctcatcgccc ttcaaatgcg ggtaggcggc aatgttatag agcgttgagg
     5701 catgaagcca gtagcgtccg ctgcgcatgg cgtcctgttc ctgacaggct ttctgctgcc
     5761 agtccatcgc ctgctttgcc cactcataaa tccagttgcc gccgcggtaa ccgatgaccg
     5821 tatcgtataa atcatcatcc gttcgctctg cgtcgctcat cacaatgcgc gcctgcacat
     5881 caaggatttc tcgtgggtca acgccgcgcc aaatccacat caggcggttt atcatgcgat
     5941 accaatgcgg gacgttctta ccgtccagcg cggattgcat gggcggctgc gacccacgat
     6001 tgaaccgacg gacaagggta gacgtttcag tatgtttaaa gcggggtttg aacagggttt
     6061 cgctgaggtt agcctgtgtc attcgtgcag cctccttgga tactcataga ggcttattgt
     6121 aaccaataaa acagcgcccg gcattgccgg gcgctctgaa aagctgctga ttaacgacct
     6181 gaaatcggcg gtacaaatac cacacccata tcccagggct gctcaatcca ggtgttctga
     6241 ggaatatcaa taacataatc atcaaccagc ggacggcccg ccggtttagc gaaaatcgtg
     6301 acgaaatgcg ctttagggta catttcgcga atcgcgacgg cggtgccgcc ggtatcgacc
     6361 agatcgtcga tgacgataaa gccttcgcca tcgccttctg cacgtttcag cactttcagt
     6421 tcgcgctggt tatcgtgatc gtagctggag atgcatacgg tatcgacatg acgaatgccc
     6481 aattcacgcg ccagtagtgc gcccggtaca aggccgccac gacttacggc aataatgcct
     6541 ttccattgtt ctgaaggcat gaggcggctc gccagtttgc gtgcgtgaat ctgcaacatg
     6601 tcccaggtga cgacgtattt ttcgctcatg tgaagtgtcc cagcctgttt atctacggct
     6661 taaaaagtgt tcgaggggga aatagttgcg cgagattata gagacctgac gcgctaaaaa
     6721 ccagtgttta gcggaatcca cgcctctttt tgtatgcttt atactacccg caggcggaga
     6781 aagtggtatt ctcagtcgca tctcgtaaga gttattaatt ccgctaaccc tgtggcctgt
     6841 aagaacgttt ttcagaccac cgccaaggag acttatcgtg tctgaactgt ctcagttatc
     6901 accacaacct ttgtgggata tttttgccaa aatctgttct attcctcacc cgtcctatca
     6961 cgaagagcaa ctcgcggaac atattgtgag ttgggccaaa gagaaaggcc tttacgtgga
     7021 tcgcgaccag gtcggtaata ttctgatccg taagcccgcc actgcaggta tggaaaatcg
     7081 caagccggtc gttttacagg cgcatctgga tatggtgccg caaaaaaata gcgacaccgt
     7141 tcacgacttc actacagatc ccatccggcc ttatattgat ggcgaatggg ttaaagcgcg
     7201 cggtactacg ctcggcgccg acaatggtat tggaatggct tctgcgttag cggtactggc
     7261 tgacgataat gtcgtccatg gcccgctgga agtgctgctg accatgaccg aagaagcggg
     7321 catggatggc gcgttcggcc tccagtccgg ctggttgcag gctgacatcc tgatcaacac
     7381 cgactctgaa gaagaaggtg agatctatat gggctgcgca ggcggcatcg attttacctc
     7441 taatctgccg ttgacccgtg aagctgtacc cgcaggattt gcatgcttta agctaaccct
     7501 gaaaggtctg aaaggcggcc actccggtgg tgaaattcac ctcggccttg gcaatgccaa
     7561 caaattgctg gcgcgttttc tggccgggca cgcagaagaa ctggatctgc gtctgatcga
     7621 tttcaacggc ggcacgctgc gtaacgcgat tccgcgcgaa gcgttcgcta ccctcgccgt
     7681 tgccacagac aacgtaggcg ctctgaaaac attagtgaac gcttaccagg atattctgaa
     7741 aaacgaactg gcggaaaaag agaaaaacct gacgctgcaa ctcaatgagg ttgccagtga
     7801 taaagccgca ttgaccgcgc cgtcacgcga tacctttgtg cgcctgctga acgcaacgcc
     7861 gaacggcgtg atccgcaatt cagacgtggc gaaaggcgta gtggaaacat cgctgaacgt
     7921 tggcgtggtc acaatgtctg atgcgaatgt cgaaattcac tgcctgattc gctctcttat
     7981 cgacagcggt aaagattatg tggtgagtat gctggattcg ctgggcaagc tggctggcgc
     8041 gaaaaccgaa gcaaaaggca gctatccggg ctggcagccc gatgcgaact cgccggtcat
     8101 gcacctggtg cgggaaacct atcagcgtct gttcaacaag acaccgaaca tccagattat
     8161 ccacgccggc ctggaatgcg gtctgtttaa gaaaccctat ccggatatgg acatggtttc
     8221 tattgggcct accattaccg gacctcactc tccggatgag caggtacata tcgaaagcgt
     8281 gggccactac tggactctgc tgaccgaatt gctgaaagcg attcctgcga agtaagaaag
     8341 cgctaaaatg cccgtctcat ttctggacgg gctatcaata tggaatatcg ggtatccatt
     8401 gccagataag ctctcctgga tgcgctgaat agcgctgcgg ctacacgcga atagccagac
     8461 agccctataa cagcgctggt agcaccgaat tattgtggcg taaacgccat tcctttaaat
     8521 atccgtagcg gattgccgcg ctcaatctga tgatggaaca gacgcctttc agacttcaac
     8581 gccgcacact cattttgccg ttgctgttcc agccgccagg caatcagcag ccgggccaga
     8641 cgcttattcg catgttgact gcgctccgac tgaaccttca cgctaatccc gctcgccagg
     8701 tgcgtggccc gcactgccga gtcggtttta ttaacgtgct gcccacccgg gccggaagag
     8761 cgcagagtct cgaaacgaat ctcatcagac tgtatgtgct cgtcggcgga aaagcgccca
     8821 atgccgacgt accagttttt tcgcccatgg tgcgggcgat acgggctggt acaaatccac
     8881 agtaacgtgc cgcaccaacg ttcactgaaa gccatggctt tttcgccgtc cagcgagacc
     8941 agcgcagaac gcagcgtgtc tggtaatcgt cccggctctg tttcaagccg tgtcagcgat
     9001 accttttctc tggcggcttc tttcgtcaga caatccagcg ctttttttac cgccagacaa
     9061 cactcgtccg gtccctgcgc agaagaaagt tgcagtaaga tcatgcgctt ttctcccctg
     9121 aggttttcag cgtcagcacc ggacgcaggc aggcaactgg cgtaatcagt ccggcgtctg
     9181 ccagacaatc cacaacgcta tcgatggatt tatacgcctg cggcgcttct tcataaatga
     9241 gctggcgatc gcggcaaatc acccggctac ccatcccagt acggcagagc tgtcgcgggg
     9301 taaattttgc cgataaccgg tctttacact cggtacgcat ccatttgcgc cccgcgccgt
     9361 gcgccaggga gaagaggctc tcctcgctga cgacgggttt caccagccag ctataatcgc
     9421 cgcgcgagcc ggggataatc accagtccct gcccatctgg cgtagcgcct ttacggtgca
     9481 gccaccccgc ctcacccgcg acagtacagg gttcaacgaa gttatgcgcc acatccagcc
     9541 gcggttcgcc ctcagccctg agctgttgca gtatccggcg ggcaatcagc gcgcgattac
     9601 tgcgggcaaa tgccagcgca tcgtcatgtt ctgcaaggta gtggcgcgca tcgtcgctat
     9661 cttccggcaa accgttatgc gaaaacgcct ccacatgacg acgcaggata gcttgcccca
     9721 gaccgcgtga accactgtgt accagcagta ataactgcgc tttttgcaac cccgacaaag
     9781 cgaacgaatc agcatcgacg atgcgatcga cctgctgcag ctcggcaaaa tgattgccgc
     9841 cgccaatgga acccagcgca gagcgccacg aatgatgctg cattacggcg gggacattct
     9901 cctccagcca ctgcgcgtcc gccacgtcag gcagcgacgc cagccgcttc tccagtttat
     9961 cggcgttata tttacgccct aaaatatccg tttgccataa cgccatgccg cagccgatat
    10021 cgttgccgac cagcgccgga taaaaacgtc cacgcgagaa aaaggctgcg ccaataggat
    10081 agccgcgccc cggatgcaga tctggcatcc cgataacgcg tttcataccg gttaacttag
    10141 ccgtcgtata taattgttgg atcgcggaat cttcgatcca caggttatcc gatgcgatag
    10201 aaaataccac atctgataaa ggacgaatat aattgcccat ataccattcc atatatgaat
    10261 taaaaaatca ggaaatggca gactaatcca gggcaataaa agaaaattaa tcctggaaag
    10321 gtctgcaaag tgcgttcaga gaataaagtg tcatgatgaa cctcctttgc agttattgag
    10381 aatgagaaaa cgcgggtata gtaatactga aatttagatg gcgcaatcgt aatagtgata
    10441 aaatcttaat agcctgactt ataaccctaa caccaactgt cgttccaact gagggtcgag
    10501 cagcgttacg tgtagcccca ccaaccgtac gccgcgctcg ccgcgacgct cgtcccaggt
    10561 tttacgggcg gtggtaatta agtcttcttt atttaattgc ggccagacat gttcctgagt
    10621 ggtttgctga aaatcattaa attttaattt aacgccctgt cgggcaatca gtaaatcggg
    10681 ctttactata gccagacgac gctccagttc cggatataaa tgttcaataa tggcctcgca
    10741 gtccgaccat tcatgaatat cctccgccag agtacgctca acgcctaccg atttacgcag
    10801 cctttcgctg ttaacatcac gctcgtcaat accctgacta cgctcccata atacccggcc
    10861 aaatttacca aagcgtttga gaagcatcgc cagatcgcac tgttgaatat ccccgcaggt
    10921 tcttaacccc atattttcca gtttggcggc ggaaactttc cccacgcctg gaattttggc
    10981 taacggcaac gttttaagaa agtcgggtac atcggctggc gtaataacat attgtccgtt
    11041 cggtttattg agatcggagg cgatcttcgc cagaaatttc actggcgcaa cgccggcgga
    11101 ggcggtgagt tgcagttcat tgaaaatagt ctgacgaatc tccctggcga tcagagttgc
    11161 cgaaccataa cagtgcgggc tgtcagtcac atccagccag gcttcatcca gcgagagcgg
    11221 ttcaatcagt gaagtgtagc gggaaaagat gtcacgtaca tgccgcgaag cctctttata
    11281 ggcgtcaaag cggccaggca gtaaggtgag atgggggcac agctttagcg ccatggcagt
    11341 cggcatcgcg ctgcgtacgc caaactggcg cgcaggatag ttggcggtac tgataacgcc
    11401 tcttcgctca cgactcccgc caatggcaat ggggatatcg cgtaacgccg gattatcacg
    11461 catctctacc gcggcaaaaa aacagtccat atcaacatgt atgattttgc gcatcgctcg
    11521 cccccacaat actgtttaag tgtacagtat gttttattgc gcgcaaagag acattcgcgt
    11581 taaaaatgcg acatattcga aggtatgacg acgaaagcgg cgggaaaatt gtaaacgtac
    11641 acacggggac ttgcgaaaaa ctgccgtggt gctaatgtga gcgctccaaa tccagattac
    11701 tccgatttgg ggactctttt gccgttctgg cgtgtgtaac cgttttatca aggaacaagc
    11761 agtatgcgta aaatcgcatt ttttcttgcg atgcttctga tgccgtgcgt ctcatttgcc
    11821 ggtttgctga gcagcagcag ccccgtcacg ccggtcagta aagagtataa gcagcagtta
    11881 atgggctcac cggtctatat tcaaattttt aaagaagagc gcacccttga tctctacgtc
    11941 aaaatgggtg agcaatacca gttgcttgat agctacaaaa tttgcaacta ttccggcggg
    12001 ttaggcccga aacgccgtca gggcgatttt aaaagtccgg aagggtttta cagcgttcag
    12061 cgtaatcaac tcaagccaga cagccgtttt tataaggcca tcaacattgg ttttcccaat
    12121 gcctacgatc gcgcgcatgg ctatgatggt aaatatctga tgattcacgg tgcctgtgtt
    12181 tccgtcggct gctatgccat gaccgacagc ggcattgatg agattttcca gtttgtcacc
    12241 gccgcgctgg tctttggtca gccaagcgta caggtgagta tttatccgtt ccggatgacc
    12301 gacgccaata tgcagcgtca taaatattca tattacaaag atttctgggc gcagctaaaa
    12361 cccggctacg attattttga acagacgcat aagccgccaa ctgtttctat cgttgatgga
    12421 cgttacgtcg tgagcaaacc gttgagtcac gaagtcgttc agccacagct ggcctcaaat
    12481 tatacgctct ccgaggcaaa ataacgccca ttcgcctggc ataatctttt gccaggtttc
    12541 attccccgtt agcggctggg tagcaatcac ggtaaccacg tcatttggcg tggtctgtga
    12601 actgaaatca atttccatat cctgatccac cagcgtggct acgccaaacg gcgcccggcg
    12661 agtgatccag tgcaaatggg ttgagcaaaa cgccatcaca tatcgcccat ctgacagcag
    12721 catgttaaaa acgccttttt cacgtaatac cgtcgccagt gtcgcaatat atttaaatac
    12781 cgctgtcatg ttgcccggcg tgcggggata acgctgcgtt aatttatgca atagccagca
    12841 aaacgctttt tcgctgtcgg tttcccccac cggacgaaaa ttaccggttt ccagcgactt
    12901 ataaccgttg agctgaccgt tatgagcata agtccagttg cgtccccata attcccgggt
    12961 aaaagggtgt gtattttcca gcgctacttc accgcgatta gcctgacgga tatgagcgat
    13021 aaccgagcag gacttgatcg ggtaattctg taccagtttc gcaatcggcg aatggtagct
    13081 cggttgcgga tctttaaacg tgcgacagcc ctttccttcg taaaaggtaa ttccccagcc
    13141 gtctttatgc ggcccggttc cgccgccacg ctgcaccagt ccggtgaagc taaagcagat
    13201 atccatcggc acattggcgc tcatcccaag cagttcgcac atacatcacc taccttaaaa
    13261 cggttaattg cctgataaga ccagcaaagc acagctcgta ggccggataa gacgcttgcg
    13321 tcgccatccg gcacaatgcc cgatggcgct tcgcttatcg ggcctactcg ttccaggccc
    13381 gataagaccg gcaaaaatta tcggcttatt taaccatctc tttttcgatc aactgaatca
    13441 ggatatgaat cactttgata tgaatttcct gaatacgatc ggcataaccg aagtgcggta
    13501 cgcgaatttc aatatccgcc gttcccgcca ttttgccgcc gtctttgccg gtcaacgtaa
    13561 tcactttcat gcctttttca cgggccgcgg caatcgcttt aatcacgtta ccagagttac
    13621 ccgacgtcga gatccctaac aggacatcgc cttcgcgccc taccgcctca acgtaacgag
    13681 agaaaatata gtcatagcca aaatcattac tgacgcagga tatatggcta acatcagaaa
    13741 tcgcaattgc cgggtagccc ggacgatttt cacgataacg acctgtcagc tcttcagcaa
    13801 agtgcatcgc atcgcaatgg gagccgccgt taccgcagga aagtacctta ccacccgctt
    13861 taaaactgtc agccaacagg accgccgcgc gctgaatggc gtgaatattg gcgtcatctt
    13921 ttaaaaaatt agccagcgtt tccgccgctt cgttcagttc gttacgaata agatcctggt
    13981 acatgaggat atccttcagc atgaatgtaa atgacagtat gcagtgtacc ggatagcagt
    14041 acaggcgaga agcataagcc gaattaacgc ctcacgcttt tgatttttcg tgcccccaaa
    14101 aacggcaaca atgtgagctt tgttgtaatt attttgtaaa cacattgcta aaagatttta
    14161 catccactac aacctaatca tcacaagtgg tcagacctcc tacaagcaag ggagcttttc
    14221 gttatgatga ttttgagtat tatcgctacg gttgttctgc tcggcgcatt gttctatcac
    14281 cgcgtgagtt tatttctcag cagcctgatt ctgctcgcct ggaccgccgc acttggcgtc
    14341 gctggcctgt ggtccatctg gctgttggtt cctctggcca ttatcctcgt gccgtttaac
    14401 ctcacaccga tgcgaaaatc aatgatttcc gcaccggtgt tccgcggctt ccgtaaggtc
    14461 atgccgccga tgtcgcgcac tgagaaagaa gcgattgatg ccggtacaac ctggtgggaa
    14521 ggcgatctgt tccagggcaa gcctgactgg aaaaaactgc acaactatcc gcaaccgcaa
    14581 ctcactgccg aagagcaagc gtttctcgac ggcccggtag aagaagcgtg ccggatggcg
    14641 aacgatttcc agattaccca tgaactggcg gatctgccgc cggaactgtg ggcttacctg
    14701 aaagagcatc gtttttttgc gatgatcatt aaaaaagagt acggcgggct ggagttctcc
    14761 gcttatgtgc agtcccgtgt actgcaaaaa ctgtccggcg tctccgggat tctggctatc
    14821 accgtcggcg ttccaaactc actcggccct ggcgagctgt tgcagcacta tggtacggaa
    14881 gagcagaaga atcactatct gccgcgactg gcgcgcggcc aagaaatccc ctgctttgcg
    14941 ctgaccagcc cggaagcagg ttctgatgca ggcgctattc cggataccgg cgtggtttgc
    15001 atgggcgaat ggcagggcca gcaggtgctg ggtatgcgtc tgacctggaa caagcgttac
    15061 attacgctgg cgccgatagc taccgtgttg ggcttggcgt ttaagctttc cgatccggat
    15121 agattgttag gcggagaaga agagctgggt attacctgcg ccctgatccc cacctcaacg
    15181 ccgggtgtgg aaattggtcg tcgtcacttc ccgcttaacg ttccgttcca gaatggccca
    15241 acccgcggta acgatatttt cgtgcctatt gattatatta tcggcggccc caaaatggcc
    15301 ggacagggct ggcgtatgct ggtggaatgt ttgtcggtag gacgcggtat taccctgccg
    15361 tccaactcca ctggcggggt gaaatccgtc gcgctggcaa ccggcgccta tgctcacatt
    15421 cgtcgtcagt tcaaaatttc tatcggcaag atggaaggta ttgaagaacc gctggcgcgt
    15481 attgcaggta acgcttatgt gatggatgcc gccgcatcgt taatcaccta cggcattatg
    15541 ctaggcgaaa aaccggcggt actgtcggct atcgtgaagt accactgcac ccaccgcggc
    15601 cagcagtcca ttatcgacgc gatggatatc actgggggta aaggcattat gctgggcgag
    15661 agcaacttcc tggcgcgtgc ttaccagggc gcgcctatcg cgatcaccgt ggaaggcgcg
    15721 aatatcctga cccgtagcat gatgatcttt ggtcagggcg ccattcgctg ccatccttat
    15781 gtactggaag agatggccgc agcgcagaat aatgatgtga atgcctttga taaactgttg
    15841 tttaaacata ttggccatgt cggcagcaat accgtccgca gtttctggct tggcctgacc
    15901 cgcggattaa cgagccatac gccaaccggc gacgccacga agcgttatta ccagcatctg
    15961 aaccgactga gcgcaaacct ggccctgctg tccgacgtgt caatggcggt actgggcggc
    16021 agcctgaaac gccgcgagcg tatctccacg cgtctgggcg atgtgttgag tcagctttat
    16081 ctggcctcag ccgtactgaa gcgttacgac gacgaaggcc gccacgaagc cgacctgccg
    16141 ctggtgcact ggggcgtaca ggatgcgctg tatcgtgctg aacaagcgat ggacgatctg
    16201 ctgcagaact tcccgaaccg cgtcgtggcc ggattgctca ccgcgatgat cttcccgact
    16261 ggccgtcatt atctggcgcc gtctgataag ctggatcacg ccgtggcgaa gatcctacag
    16321 gtgccgaacg ccacacgttc acgtattggg cgcggtcagt atctgacgcc cgccgaacat
    16381 aatccggtcg gtttactgga agaagcgctg cgtgatgtca tcgctgccga ccctatccac
    16441 cagcgcatct gcaaagaact gggtaaaaat ctgccgttta ctcgtctgga tgaactggcg
    16501 cgcaatgcgc tggcgaaagg gcttatagat aaagatgaag ccgccatcct ggcgaaagcg
    16561 gaagagagcc gcctgcgcag tatcaacgtt gatgattttg aacctgaagc gctggcgacc
    16621 aaaccggtaa agctgccgga gaaagtgcgt aaagtcgaag ccgcataatc agtctcgtgt
    16681 ctttcctgcc ccgctttcgc ggggcttttc ttgccgcttt tttattattg ctcatgctac
    16741 agtgtaaaga cgctgttcaa tgaggagctc cgatcgtgtc tggtttgaaa attactctgt
    16801 tgcaacaacc tttagtctgg atggacggcc tggcaaacct gcgtcatttt gacagacagc
    16861 tagagctcgt atctggccgg gatgtgattg ttctgcctga aatgtttacc accggcttcg
    16921 cgatggaggc cgctaataac tcactttcgc aagatagcgt gattacgtgg atgcaggcca
    16981 aagcccgaca aactgacgct ctgattgccg gcagcgcggc gctacaaact gagcgcggcg
    17041 ccgtaaatcg cttcttactg gttgaaccgg aaggcaaagt tcatctctat gataagcgcc
    17101 atctgtttcg tatggcggat gaacatcaac attatgccgc aggcgataaa cgcatcatcg
    17161 tgcagtggcg cggttggcgc atcctgccgt tgatctgtta cgatctgcgc tttccgatat
    17221 ggtcgcgcaa ccgcaatgat tacgatctgg cgctgtatgt agcgaactgg cccgcgccgc
    17281 gctcgctaca ctggcaaaca ttactgacgg cgcgcgctat tgaaaatcag gcttatgtcg
    17341 caggctgcaa ccgggttggc accgatggca acgggttaca ttatcgcggc gatagccgaa
    17401 tcattaatcc ccagggcgac attatcgcca ccgccgaacc acaccaggcg acacgtatcg
    17461 atgcagatct ttctctcgtc gccttgcagg actatcgcga aaaatttcca gcctggcgcg
    17521 atgccgatcc attcaccttg taagcaacct gccgctcacc gcggcgggat tgtttcactc
    17581 cgtaactctc cgtaaaacaa attcgcgtgg cgtaatgtgg caggcaacgt attctgacta
    17641 agagcctatc ccaccaggcg ttattggcgc agtcagtttg gacacggaca gcgcgcaaaa
    17701 accggagcgt acacgtagta cgtgaggatt ttgagcactg cccaggtcca aaatggcaag
    17761 taaaatagcc ctaatgggat aggctctaag ataattgctc gccattcgtg ggtaataaaa
    17821 acggttaatc actcccttat caggatatct tcatgaaaaa ctttgtacgc acaactttac
    17881 tggcagcgac tctggcgggc gtttcttttg gcgctttcgc caccgctgtt cccaatcctc
    17941 ccctgcccgc ccaggatcct attgtccagc atctgaagct gacaaacgat cagattaccc
    18001 ggatcaaaaa acttcaccaa caactggaaa ccgacgtcag tcagatttct atgaagggaa
    18061 ttaaagacgg tgcgctgata gaggtgatta aatccggtaa atgggatgac gccgccgtaa
    18121 aacagcagct tgcagccttc agtaacatag aacaacaggc tcgctattat cgggttaaat
    18181 attattttga tttaagcaaa gtcttaacac cagaacagcg tcaacaggta caacaagatc
    18241 tcgcccaagc acttgagtaa atatttttgc ccgttattcc tggataacgg gctttatcca
    18301 ggtcgggtac aaattcatct ttttcttaca gcatcgcacc atctcacact acccgttaca
    18361 caacgtagaa gtgaaaccgt acgtggggca atttggcgag gagatggatt tccataccga
    18421 cgattatcgt attgttattt aaaatcttca tctcattttt tacccgctta cagaaaaccc
    18481 agcgttacaa tagaccgttt tttgggcttc gtttatgtaa tcgttatatc acaccctata
    18541 ccgtgaaact tgtcttttag cccaatatta aggcaggttc tgaaatgaaa aactttttcg
    18601 cagtctgcat cattcccctt gtggtaacct ggtccgctac tgcatcagca aaagaaggga
    18661 tctatatcac cgggaaagcg gggacatccg tagtcaatgt ctatggaatc aactcaacct
    18721 tcagccagga ggagatagtc aatggtcatg caacgttacc tgaccgtacc aaaggcgttt
    18781 ttggcggcgg ggttgctatc ggttatgact tttatgatcc attccagctt ccagtacgtt
    18841 tagaactgga taccactttc agaggtgaga cggatgctaa aggcgggcag gatattattg
    18901 catttggtca gccagtacac ataaatgtaa aaaatcaggt ccgaatgacc acttacatag
    18961 ttaatggtta ttatgatttt cacaatagta cggcatttac accctatatc agcgcaggcg
    19021 ttggcctcgc tcatgtgaag ctaagtaata acaccattcc tgttggtttt ggtattaatg
    19081 aaactctgtc tgcttcaaaa aataactttg cctggggcgc aggtatcggt gcaaaatatg
    19141 ctgtaacaga taatattatg attgacgcca gttataaata cattaatgca ggcaaagtga
    19201 gcatttcaaa aaatcactat gctggtgatg aacataccgc ttatgatgca gacacaaagg
    19261 ctgcctccaa tgacttcatg ctcggcatta cttacgcctt ttaaacacta tcggtaaaat
    19321 agctggtcct gtgggttccc gaaggcgcaa tggaggatat cagtaatgaa tactcctgcg
    19381 ccttcagaaa atcgttgaac aggtgcaacc tggcgccatt tttcagtaca ctgcaacgtt
    19441 tctggtatgg gcttaacttc cggctaccca aaaacagtcc cgtcctgttg tatgatctct
    19501 aaatgtgaat ggcacgatta tgcgagatac ttacaagtgt ctggtatgaa gatatactgc
    19561 gaacgccgat gtaaacggcg cgcgtaacat tttagagcgg gacacgccgt gcttgcctgt
    19621 ggaaggagcg tgcagtcagg cagcccgttg gagcaggaac ccacgccctt caggacgtgg
    19681 aggatgtcaa tgcacaagaa ttggggaatc tttagcagaa tttattatct ctacagtagc
    19741 atctctcttg ttcccgtcat aaataaccca atgcctccag atctgaaacc gccttcagca
    19801 tgagcactgg ctgcaaataa caccaaataa aataataata taacaactac cgagacaaaa
    19861 aacacctctc taaagtattt agaattcata cagtcagctc atttaaattt aacgtcacat
    19921 gcaaccatgc atgcgtaaaa caagaaccac actcatatta ataatgatta gtaatgtgag
    19981 tgtgcgtata acgagataca gatgtatatt ccttaatgta acggaacatc atcaatgcaa
    20041 atagcaacca tc
//
LOCUS       DAJVBX010000071        20040 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.071, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000071 DAJVBX010000000
VERSION     DAJVBX010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 20040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20040
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.071"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            134..604
                     /locus_tag="OPV72_002186"
     CDS             134..604
                     /locus_tag="OPV72_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019077605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase-dependent protein"
                     /protein_id="HCR9914473.1"
                     /translation="MKKQQGYTLIETVVAMSLIIILSATGLYGWQRWQQQQRLWQTAC
                     QVRDYLLQLREDAHWHNRDHILRVVSEGGSWCFVSSVATQTSCTPSSPFVFTPDWRDV
                     VLADITPSLAFFGLRNTAWAGHIVLKNAAGEWRLVVSSWGRIRLCERNEAATCQ"
     gene            595..1158
                     /locus_tag="OPV72_002187"
     CDS             595..1158
                     /locus_tag="OPV72_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase-dependent protein"
                     /protein_id="HCR9914474.1"
                     /translation="MSITTRGFSLLEVVLAMAIGSILLLGSARFLPALQREIWHNTRQ
                     LSLEDEIWQRTYTVAKHLQRAGYCHGHCIGEGLHLAEQGQCVIVQWDGNNNGVWDTIP
                     AKEADQTGFRMKDNVLETLRGATSCQGKGWEKMTDPNTVLITAFNVERRDITGFSPVL
                     MLHLRGASKAEPQTVIDAQYSVTGFNL"
     gene            1155..1562
                     /locus_tag="OPV72_002188"
     CDS             1155..1562
                     /locus_tag="OPV72_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2509 family protein"
                     /protein_id="HCR9914475.1"
                     /translation="MNRERGASSLILALLILILGSLLLQGVNQQQASYAARVTTQSMA
                     IQRQALVQSALEWGRGQLWSGVTEMECRRYSSSGARVCLRRLSGDEVVMAAQDDGMTL
                     WRLGNVIQGSIVFSPHGWSDFCPLKEVALCRIP"
     gene            1547..1867
                     /locus_tag="OPV72_002189"
     CDS             1547..1867
                     /locus_tag="OPV72_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HCR9914476.1"
                     /translation="MSHPLNFQRGFSLPEVLVAMVLMVMIVTALSGYQRVLMHTFALR
                     HQYLQIWRQAWQQTALYPFSPADGWNANRMQTTQSGCVSISVTMVSPSGRQGQMTRLH
                     CPNR"
     gene            1883..5254
                     /gene="recC"
                     /locus_tag="OPV72_002190"
     CDS             1883..5254
                     /gene="recC"
                     /locus_tag="OPV72_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461913.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit gamma"
                     /protein_id="HCR9914477.1"
                     /translation="MLRVYHSNRLDVLEALMEFIVERERLDDPFEPEMILVQSTGMAQ
                     WLQMTLSQKFGIAANIAFPLPASFIWEMFVRVLPDIPKESAFSKQSMSWKLMTLLPQL
                     LDKDEFVLLRHYLTDDTDKRKLFQLSARAADLFDQYLVYRPDWLTQWEAGKTVEGLGE
                     AQNWQAPLWKALVEYTAALGQPRWHRANLYQRFIQTLESATACPPGLPSRVFICGISA
                     LPPVYLKALQALGKHIEIHLLFTNPCRYYWGDIKDPAWLAKLMARQRRHSFEDRHLPL
                     FRENQNPEALFNSDGEQDIGNPLLASWGKLGRDYIYLLSELENSQELDAFVDITPDNL
                     LHRIQADILELESHAVAGVNLEEYSRSDNKRLLDPEDNSLSFHVCHSPQREVEILHDR
                     LLAMLEADPTLTPRDIIVMVADIDSYSPFIQAVFGSAPTERYLPYAISDRRARQSHPV
                     LQAFISLLSLPDSRFVSEDVLALLDVPVLAARFTINEEGLRYLRLWVNESGIRWGIDD
                     DNVRELELPATGQHTWQFGLTRMLLGYAMESAQGEWQSVLPYDESSGLIAELVGHLAS
                     LLMQLNIWRRGLAQERPLEEWLPVCRDMLNDFFLPDADTEAAMTLIEQQWQAIIAEGV
                     AAEYGDAVPISLLRDELAQRLDQERISQRFLAGPINICTLMPMRSIPFRVVCLLGMND
                     GVYPRQLAPLGFDLMSQKPMRGDRSRRDDDRYLFLEALISAQQTLYISYIGRSIQDNS
                     ERFPSVLVQELVDYIGQSHYLPGDETLTCDESEARVKAHITRLHTRMPFDAQNYQPGE
                     QQSYAREWLPAASQSGKAHSDFVQPLPFTMPETLTLESLQRFWAHPVRAFFQMRLQVN
                     FRSEESEIPDAEPFELEGLTRYQLNQQLLNTLVEEDDAERLFRRFRAAGELPYGAFGE
                     IFWDAQCQEMQQLASRVIACRKPSQSLEVDLLCNGVQLTGWLPQVQEDGLLRWRPALI
                     SVAQGVQLWLEHLVYCASGGSGESRLFLRKEGEWRFPPLDKTQAMAYLAQLIEGYREG
                     MSSPLLVLPESGGAWIKACYDAENDVMLDDDDTLQKARTKFLQAYEGNMMVSGEGEDI
                     WYQRLWRQLESETLQAIIAQSRHYLLPLFRFNQSR"
     gene            5432..8320
                     /gene="ptrA"
                     /locus_tag="OPV72_002191"
     CDS             5432..8320
                     /gene="ptrA"
                     /locus_tag="OPV72_002191"
                     /EC_number="3.4.24.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pitrilysin"
                     /protein_id="HCR9914478.1"
                     /translation="MPRSTWFKALLLLVALWGPAVQADIGWQPLQETIRKSDKDTRQY
                     QAIRLDNDMVVLLVSDPQAVKSLSALVVPVVSLEDPEAHQGLAHYLEHMCLMGSKKYP
                     QADSLAEYLKRHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAAPLLNKKYAE
                     RERNAVNAELTMARTRDGMRMAQVSAETINPAHPGSHFSGGNLETLSDKPGNPVQQAL
                     IAFHEKYYSSNLMKAVIYSNKPLPELASIAAATYGRVPNKQIKKPEITVPVITEAQKG
                     IIIHYVPALPRKVLRVEFRIDNNSAQFRSKTDELVSYLIGNRSPGTLSDWLQKQGLVE
                     GISADSDPIVNGNSGVFAISATLTDKGLANRDEVVAAIFSYLNTLREKGIDKRYFDEL
                     AHVLDLDFRYPSITRDMDYVEWLADTMIRVPVAHTLDAANIADRYDPAAIKNRLAMMT
                     PQNARIWYISPQEPHNKIAYFVDAPYQVDKISEQTFKNWQQKAQGIALSLPELNPYIP
                     DDFTLIKNDKNYVRPELIVDKADLRVVYAPSRYFASEPKADVSVVLRNPQAMDSARNQ
                     VLFALNDYLAGMALDQLSNQAAVGGISFSTNANNGLMVTANGYTQRLPQLFLALLEGY
                     FSYDATEEQLAQAKSWYTQMMDSAEKGKAYEQAIMPVQMISQVPYFSRDERRALLPSI
                     TLKEVMAYRNALKTGARPEFLVIGNMSEAQATSLAQDVQKQLAANGSAWCRNKDVVVE
                     KKQSVIFEKAGSSTDSALAAVFVPVGYDEYVSAAYSAMLGQIVQPWFYNQLRTEEQLG
                     YAVFAFPMSVGRQWGMGFLLQSNDKQPSYLWQRYQAFFPDAEAKLRAMKPEEFAQIQQ
                     AIITQMRQAPQTLGEEASRLSKDFDRGNMRFDSRDKIIAQIKLLTPQKLADFFHQAVV
                     EPQGMAILSQIAGSQNGKAEYVHPTGWKVWDNVSALQQTLPLMSEKNE"
     gene            8313..11858
                     /gene="recB"
                     /locus_tag="OPV72_002192"
     CDS             8313..11858
                     /gene="recB"
                     /locus_tag="OPV72_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit beta"
                     /protein_id="HCR9914479.1"
                     /translation="MNDVAETLDPLRLPLTGERLIEASAGTGKTFTIAALYLRLLLGL
                     GGSAAFPRPLTVEELLVVTFTEAATEELRGRIRSNIHELRIACLRESTDNPLYARLLE
                     EISDKKQAAQWLLLAERQMDEAAVFTIHGFCQRMLSLNAFESGMLFEQQLIEDESLLR
                     YQACADFWRRHCYPLPRDIAQVVFDVWKGPKALLKDIDRYLQGEAPVIKAPPSQEETL
                     ASRHEQILARINQVKQQWCEAVSELDALIESSGIDRRKFNRGNQAKWIEKITAWAQEE
                     TKNYQLPEALGKFSQRFLAERTKAGGVTPQHPLFVAIDNLLGEPLSIKDLVLTRALSE
                     IRETVAQEKRRRGELGFDDMLSRLDTALRSESGEALAAAIRTRFPVAMIDEFQDTDPQ
                     QYRIFRRIWRHQPDTALLLIGDPKQAIYAFRGADIFTYMKARSEVSAHYTLDTNWRSA
                     PGMVNSVNKLFSQMNDAFMFRDIPFSPVKFAPRNQSLQFKVNDAPQPAMTLWLMEGES
                     CGSGDYQSYMAQVCATQIRDWLRAGQTGDALLTNGDSSRPVRASDISVLVRSRREAAL
                     IRDALTLLAIPSVYLSNRDSVFETLEAQEMLWVLQAVMAPERENTLRSALATSMMGLT
                     ALDIETLNNDENAWDAVVEEFDGYRQIWHKRGVMPMLRALMSARNIAENLLATAGGER
                     RLTDILHISELLQEAGSQLESEHALVRWLAQHILEPDSNASSQQLRLESDKHLVQIVT
                     IHKSKGLEYPLVWLPFITHFRVQDQAFYHDRHSYEAVLDLSHAEESIALAEAERLAED
                     LRLLYVALTRAVWHCSLGVAPLVRRRSDKKGETDVHQSALGRLLQKGEPMDAAGLRAC
                     IEALCDEDIVCRTPGNTDNDRWQIAAASHAELSARTLQRLLYDSWRVTSYSGLQQRGH
                     SVAQDLIPRLDIDAAGVGEAAEAPAMTPHHFPRGASPGTFLHSLFEELDFTQPIDPQW
                     VQEKLELSGFETRWEPVLTRWLDTVLHVPLNETGVSLSVLTEREKQVEMEFYLPIAQP
                     LTAGELDALIRRYDPLSAGCPALDFMQVRGMLKGFIDLVFRYEGRYYLLDYKSNWLGE
                     DSAAYTQTAMAAAMQAHRYDLQYQLYTLALHRYLRHRMANYDYERHFGGVIYLFLRGV
                     DSERPQQGIFTTRPAAALINQLDDMFAGEMSEEAQ"
     gene            11855..13690
                     /gene="recD"
                     /locus_tag="OPV72_002193"
     CDS             11855..13690
                     /gene="recD"
                     /locus_tag="OPV72_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit alpha"
                     /protein_id="HCR9914480.1"
                     /translation="MTIQKRLLEAVEQKLLRPIDAQFALTVAGNDDPAVTLAAALLSH
                     DAGEGHVCLPLSRLTLTEEAHPLLVAWISETATPIDWKKRLLASAAVSCGDSPAPLIL
                     CGDRLYLNRMWCNERTVARFFNEVNQAIAVDEDQLSRILDALFPPTDEVNWQKVAAAV
                     ALTRRISVISGGPGTGKTTTVAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGA
                     ALRQLPLTDAQKKRIPEDASTLHRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDL
                     PMMSRLIDALPPHGRVIFLGDRDQLASVEAGAVLGDICAYVNAGFTAERARQLSRLTG
                     SAIPAGAGTQAASLRDSLCLLQKSYRFGSDSGIGKLAAAINCGDRSAIQAVFQQGFSD
                     IEKRTLQSSDDYAGMLDEALAGYGRYLRLLHEKAAPEAILQAFNEYQLLCALREGPFG
                     VRGLNDRIEQAMVQQRKIQRHPHSRWYEGRPVMIARNDSALGLFNGDIGIALDRGQGL
                     RVWFVMPDGTIKSVQPSRLPEHDTTWAMTVHKSQGSEFDHAALILPSQRSPVVTRELV
                     YTAVTRARRRLSLYADERILAGAIVTRTERRSGLATLFDEVSRIG"
     gene            complement(13793..15124)
                     /gene="argA"
                     /locus_tag="OPV72_002194"
     CDS             complement(13793..15124)
                     /gene="argA"
                     /locus_tag="OPV72_002194"
                     /EC_number="2.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino-acid N-acetyltransferase"
                     /protein_id="HCR9914481.1"
                     /translation="MIKERKTELVEGFRHSVPYINTHRGKTFVIMLGGEAIEHDNFSS
                     IVSDIGLLHSLGIRLVVVYGARPQIDANLAAHHHEPIYHKNTRVTDAKTLELVKQAAG
                     LLQLDITARLSMSLNNTPLQGAHINVVSGNFTIAQPLGVDDGVDYCHSGRIRRIDEDA
                     INRQLDNGAIVLMGPVAVSVTGESFNLTSEEIATQLAVKLKAEKMIGFCSSQGVTNSE
                     GGIISELFPNEAQARVEELEAQGDYNSGTVRFLRGAVKACRSGVRRCHLISYQEDGSL
                     LQELFSRDGIGTQIVMESAEQIRRATINDIGGILELIRPLEQQGILVRRSREQLEMEI
                     DKFTIIQRDNMTIACAALYPFVEEKIGEMACVAVHPDYRSSSRGEVLLERVAAQARQM
                     GLRKLFVLTTRSIHWFQERGFTPVDIELLPESKKKMYNYQRRSKVLMADLG"
     gene            15357..16610
                     /gene="amiC"
                     /locus_tag="OPV72_002195"
     CDS             15357..16610
                     /gene="amiC"
                     /locus_tag="OPV72_002195"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase AmiC"
                     /protein_id="HCR9914482.1"
                     /translation="MSGANSAISRRRLLQGAGAMWLLSVSQVGLAAVSQVVAVRIWPA
                     SSYTRVTVESNRLLKYKQFALSNPDRVVVDIEDVNLNSVLKGIGAQIRSDDPYIKSAR
                     VGQFDPKTVRMVFELKQNVKPQLFALAPVAGFKERLVIDLYPANAQDMQDPLLALLED
                     YNKGDLDKQVPPSQSGPQPGKAGRDRPIVIMLDPGHGGEDPGAIGKYKTREKDVVLQI
                     ARRLRALIEKEGNMKVYMTRNEDIFIPLKVRVAKAQKQRADLFVSIHADAFTSRQPSG
                     SSVFALSTKGATSTAAKYLAQTQNASDLIGGVSKSGDRYVDHTMFDMVQSLTIADSLK
                     FGKAVLKQLGKINDLHKNKVEQAGFAVLKAPDIPSILVETAFISNIEEERKLKTATFQ
                     QQVAESILAGIKAYFADGATLARRS"
     gene            complement(16720..16796)
                     /locus_tag="OPV72_002196"
     tRNA            complement(16720..16796)
                     /locus_tag="OPV72_002196"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16760..16762),aa:Met,seq:cat)
     gene            complement(16826..16902)
                     /locus_tag="OPV72_002197"
     tRNA            complement(16826..16902)
                     /locus_tag="OPV72_002197"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16866..16868),aa:Met,seq:cat)
     gene            17110..18207
                     /gene="mltA"
                     /locus_tag="OPV72_002198"
     CDS             17110..18207
                     /gene="mltA"
                     /locus_tag="OPV72_002198"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008785702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein transglycosylase A"
                     /protein_id="HCR9914483.1"
                     /translation="MKGRWAKYVATGVMLAMLAACSSKPTDRGQQYKDGKFTQPFSLV
                     NQPDAVGAPINAGDFAEQVDQIRSASPRLYTNQSNVYNAVQNWLRSGGDTRTMRQFGI
                     DAWQMEGTDNYGNVQFTGYYTPVVQARHTRQGAFQYPIYSMPPKRGRLPSRAQIYAGA
                     LSDKYILAWSNSLMDNFIMDVQGSGYIDFGDGSPLNFFSYAGKNGWPYRSIGKVLIDR
                     GEVKKEDMSMQAIREWGEKHSEAEVRELLEQNPSFVFFKPQSFAPVKGASAVPLIGRA
                     SVASDRSIIPPGTTLLAEVPLLDNNGKFSGQYELRLMVALDVGGAIKGQHFDIYQGIG
                     PDAGHRAGWYNHYGRVWVLKSAPGAGNVFSG"
     gene            18316..19122
                     /gene="tcdA"
                     /locus_tag="OPV72_002199"
     CDS             18316..19122
                     /gene="tcdA"
                     /locus_tag="OPV72_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA cyclic N6-threonylcarbamoyladenosine(37)
                     synthase TcdA"
                     /protein_id="HCR9914484.1"
                     /translation="MSVVISDAWRQRFGGTARLYGEKALQRFAEAHICVVGIGGVGSW
                     AAEALARTGIGAITLIDMDDVCVTNTNRQIHALRDNVGLAKAEVMAERIRQINPECRV
                     TVIDDFITPDNVAGYMDAGFTYVIDAIDSVRPKAALIAYCRRYKVPLVTTGGAGGQID
                     PTQIQVADLAKTIQDPLAAKLRERLKHNFGVVKNSKGKLGVDCVFSTEALVYPQADGS
                     VCAMKATAEGPKRMDCASGFGAATMVTATFGFVAVSHALKKIMAKAARQE"
     gene            complement(19174..>20040)
                     /gene="rarD"
                     /locus_tag="OPV72_002200"
     CDS             complement(19174..>20040)
                     /gene="rarD"
                     /locus_tag="OPV72_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461905.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter RarD"
                     /protein_id="HCR9914485.1"
                     /translation="ILWGLTPLYYQYLSGGNLAQILIYRVFWSIPLLLAVRLLFRQRT
                     RFHDAWKDKKSFFFCMIAGLLMIVSWSSFIYALTHHLVLDASLGYFINPLFVIALGCI
                     FLKEKLSLFQAIAVFSGVCGLTFQIIMLRHFPALALTMGLSFALYGLARKFIHYDVMT
                     SITIETLWALPVSLLIFLFSDTGPIISANTPFFLYVMTAPVTIIPLVLFAIALNHTSL
                     IVTGLAQYIEPSLQFLLAIMIFGEHINYAELLCFCAVWFGLFLCISENLYSHYLRARL
                     KPVFGRVQRFFR"
BASE COUNT         4667 a         5003 c         5720 g         4650 t
ORIGIN      
        1 cctttgtctc aatcttcggc gcggattcct gaaattttgc aacgcgctgc aagacatgaa
       61 cttttttccg taacgcgtcg aacaatctgt atttggcgct cgttattttt cttccgcccg
      121 ccatactgcc gacatgaaaa aacaacaggg ctatacgctc attgaaacgg tggtcgcgat
      181 gtcgctcatt atcattctca gcgccacagg actttatggc tggcaacgct ggcagcagca
      241 acagcgcctg tggcaaaccg catgtcaggt gcgggattac ctgctgcaac ttcgtgagga
      301 cgctcactgg cataaccgcg atcacattct tcgcgtggtc agcgaaggcg gttcatggtg
      361 ctttgtcagc tctgttgcta cgcaaacatc gtgtacgcca tcttccccct ttgtgtttac
      421 gcccgactgg cgtgatgtcg tccttgccga tatcacgccg tcgttagcct tctttggcct
      481 gcgcaatacg gcatgggcag ggcacatcgt gctgaaaaac gctgccggag agtggcgtct
      541 ggtcgtctcc tcctgggggc gaatcaggct atgtgagcgt aacgaggccg ccacgtgtca
      601 ataaccacgc gggggttctc gctactggag gttgtgctgg cgatggcgat aggttccatt
      661 ttactgcttg ggtccgcacg atttttaccg gcgttacagc gtgagatctg gcacaacacg
      721 cgacagttat cgctggaaga tgaaatctgg cagcgaacct ataccgtagc gaagcatctt
      781 caacgtgcgg gttactgtca tggccactgt atcggcgaag ggctacatct tgccgaacag
      841 gggcaatgcg tcatcgttca gtgggacggg aataataacg gggtctggga taccataccg
      901 gcgaaagagg ccgaccagac cgggttccgt atgaaggata acgttctgga gacattacgc
      961 ggagcaacat cttgccaggg taagggatgg gaaaaaatga ccgatcccaa tacggtactc
     1021 atcacggcgt ttaacgttga gcgccgggat ataacgggat tctcgccagt gctcatgctg
     1081 catctgcgtg gcgccagcaa agccgagcct cagacggtta ttgacgcgca atatagcgta
     1141 acgggattta atctgtgaat cgggaacgtg gcgcttcttc gctaatactg gcgcttttaa
     1201 tactgattct gggcagtctg ctactgcaag gcgtaaatca gcagcaggcc agctatgccg
     1261 cccgcgtgac gacgcagagc atggcgatac aacgccaggc gctcgtacag tcggcgctgg
     1321 aatgggggcg agggcagcta tggtcaggcg taaccgaaat ggaatgtcgg cgctattcct
     1381 cttcaggagc gagggtctgt ttgcggagat tatcggggga tgaagtggtg atggcggcgc
     1441 aagatgatgg catgacgtta tggcgtttgg gcaacgtcat tcagggaagc attgtctttt
     1501 ctccccacgg ctggagtgat ttttgtccgt taaaagaggt ggcgttatgt cgcatcccct
     1561 gaattttcaa cgcgggttta gcctcccgga agttttagtg gcgatggttc taatggtaat
     1621 gatcgtcacc gcgctgtcag gctatcagcg ggtattaatg cacacttttg cattacgaca
     1681 ccagtatctc cagatctggc ggcaggcgtg gcagcaaacg gcgctgtatc cattttcgcc
     1741 tgctgacggc tggaatgcca accggatgca gacaacgcaa tcgggatgtg tcagcatcag
     1801 cgtcacgatg gtttcaccct ctggcaggca ggggcagatg acgcgcttgc attgtccaaa
     1861 tcgttaatcg tcaggagtaa ttatgttaag ggtctaccac tccaatcgtc tggatgtgct
     1921 ggaagcgttg atggagttca tcgtcgaacg cgagcggctg gatgatccct ttgaaccaga
     1981 aatgattctg gtacaaagca cgggtatggc gcagtggctg cagatgaccc tttcacaaaa
     2041 gtttggtatt gcggcgaata tcgcttttcc gttaccggcg agttttatct gggagatgtt
     2101 tgtccgcgtg ttgccagata tccccaaaga aagcgctttc agcaaacaaa gcatgagctg
     2161 gaaactgatg accttgctgc cgcagttgct ggataaggat gagtttgtac tgctgcgcca
     2221 ttatctgacc gacgacaccg ataaacgcaa actctttcag ctttccgcgc gcgccgccga
     2281 cctgttcgat cagtatctgg tttatcggcc tgactggctt acgcagtggg aggcgggaaa
     2341 aaccgtggaa ggtctgggag aggcgcaaaa ctggcaggcg ccgctgtgga aagcattggt
     2401 ggaatatacc gccgcgctgg ggcagccgcg ctggcatcgc gccaatctct accaacgctt
     2461 tattcaaacg ctggaaagcg cgaccgcctg cccgccaggg ttgccgtccc gcgtttttat
     2521 ttgcggcatt tccgcgttac cgccagtgta tctcaaagca ttgcaggcgc tgggtaaaca
     2581 tattgaaatc catctccttt ttactaatcc gtgtcggtat tactgggggg atataaaaga
     2641 cccagcctgg ctggcaaaac tcatggctcg ccagcgtcgt cacagttttg aagaccgtca
     2701 tttaccgttg ttccgtgaaa atcagaatcc ggaagcctta tttaacagcg acggtgaaca
     2761 ggatatcggt aatccgctac tggcctcatg gggaaaactg ggacgggatt atatctacct
     2821 gctatctgaa ctggaaaaca gccaggagct ggatgcgttt gttgatatta cgccagataa
     2881 tcttttgcat cggattcagg cggatatcct tgaactggaa agccatgcgg tggcgggcgt
     2941 aaatcttgag gagtattcgc gcagcgacaa taagcgtctg ctcgatcccg aggataacag
     3001 cctctctttt cacgtttgtc acagcccgca gcgcgaggtg gaaatactgc acgatcgcct
     3061 gctggcgatg ctggaagccg atccgacgct aacgccgcgc gacattatcg ttatggtggc
     3121 tgatattgac agctatagcc cgtttatcca ggcggtattt ggtagcgcgc caacggagcg
     3181 ctatctgcct tatgctattt ccgatcggcg ggcgcgtcag tcacatccgg tgttacaggc
     3241 atttatcagt ctgctttcgt taccggacag ccgcttcgtc tccgaggatg ttctggcgtt
     3301 gttagacgta ccggtattgg ctgcccgctt tacgatcaac gaagaagggc tgcgttattt
     3361 gcgcttgtgg gtcaatgagt caggcattcg ctgggggatt gacgatgaca acgtgcgcga
     3421 gctggaactt cctgccacgg ggcagcatac atggcaattt ggcctgacgc gtatgctgct
     3481 ggggtatgcg atggaaagcg cccagggcga gtggcagtcg gttctgcctt atgacgaatc
     3541 cagcggtctg attgctgagc tggtcgggca tctggcttcg ctgctgatgc agcttaatat
     3601 ctggcggcgc ggtctggcgc aggagcgacc tctggaagag tggttgcccg tttgtcgcga
     3661 catgctcaat gatttcttcc tgcccgatgc ggacacggaa gcggcaatga cattgattga
     3721 acagcagtgg caggccatta tcgccgaagg cgtcgcggcg gaatatggcg acgcggtacc
     3781 gatttcgcta ctgcgggatg agctggcgca gcgtctggat caggaacgta ttagccagcg
     3841 cttcctggcg ggccccatca atatttgtac gctgatgccg atgcgttcca ttccgttcag
     3901 agtcgtttgc ctgctgggaa tgaacgacgg cgtatacccg cgccagcttg cgccgttggg
     3961 ctttgacctg atgagccaaa aacccatgcg cggggatcgt agccgtcgcg acgatgaccg
     4021 ctacctgttt ctggaagcgt taatctcggc gcagcagacg ctgtatatca gctacatcgg
     4081 tcgctccatc caggataata gcgaacgctt tccctctgta ctggtgcaag aattggtgga
     4141 ttacatcggg caaagccact atttgccggg cgacgaaacg ctgacctgtg atgagagcga
     4201 agcacgagtc aaagcgcata ttacgcgtct gcatacccgt atgccttttg atgcgcaaaa
     4261 ttaccaaccc ggcgaacagc aaagttatgc cagagagtgg ttgcccgcgg cgagtcagtc
     4321 gggaaaagcg cattctgact ttgtgcagcc gcttcctttt acgatgccgg aaacattgac
     4381 tctggaaagt ctgcagcgtt tttgggccca tccggtacgc gcattttttc agatgcggct
     4441 tcaggttaat ttccgctcgg aagagagtga gattcctgat gctgaaccgt ttgaattaga
     4501 gggattgacg cgatatcaac ttaaccaaca gttgctcaat acgttggttg aagaggacga
     4561 tgccgaacgc ttgttccgcc gttttcgggc tgcgggagag ctgccttacg gcgcgtttgg
     4621 cgaaatattc tgggatgcgc agtgtcagga gatgcagcaa ctggcaagcc gggttatcgc
     4681 ttgccgtaag ccgagccaaa gcctggaagt ggatctgctt tgcaatggag ttcagctaac
     4741 cggctggcta ccgcaggtac aggaggatgg attattgcgc tggcgtcccg ctttaatcag
     4801 cgtggcgcaa ggtgtgcaac tttggctgga acaccttgtc tattgtgcca gcggcggtag
     4861 tggcgaaagt cgcctgtttt tgcgcaaaga gggagaatgg cgatttccgc ctcttgataa
     4921 aacgcaggca atggcttacc tggcgcaact gattgaaggc taccgggaag gcatgtcttc
     4981 tccgctattg gtactgccgg aaagcggcgg cgcatggata aaagcctgtt atgacgctga
     5041 aaatgatgtc atgttagacg acgatgatac tttacagaag gccaggacaa agtttctaca
     5101 ggcttatgaa ggcaacatga tggtgagcgg cgaaggcgaa gatatctggt atcaacgtct
     5161 ttggcgtcag ctggaatcgg aaacgttgca ggctatcatt gcgcagtcac ggcattacct
     5221 gttaccgctg tttcgtttta atcagtctcg ttgattgtat gaaaatcgcg ccattaaaag
     5281 gcttcgacta tgatgcgctc ttcgtcacgg actgattact gataaaaaaa tgctgcctgg
     5341 ttcagcacaa taatatcccg ttccgctcag gtcgatggtt tacgtgacca tacagatgag
     5401 tgggaatgaa agttaatgat gaggtccgtg aatgccccgc agcacctggt tcaaagcgtt
     5461 attgttattg gtcgccctct gggggcctgc agttcaggcg gatatcggtt ggcaaccgct
     5521 gcaagaaact atccgtaaaa gcgataaaga tacccggcag tatcaggcga tacgtcttga
     5581 taatgacatg gtggtgttgc tggtatccga tccgcaggct gtaaagtctc tttctgcgtt
     5641 agtggtgccc gttgtatcgc ttgaagatcc tgaggctcat caggggcttg ctcattatct
     5701 tgagcatatg tgcctgatgg ggtcaaaaaa atatccgcag gcggatagcc ttgccgaata
     5761 ccttaaaaga catggcggta gccacaacgc cagcaccgca ccttatcgaa cagccttcta
     5821 cctggaggtt gaaaacgacg cgcttccagg tgccgtagat cgcttggccg acgccattgc
     5881 cgcgccattg ctcaataaaa agtatgccga acgcgaacga aacgcagtga atgccgagct
     5941 gacgatggcg cgcacccgtg acggtatgcg tatggcgcag gtaagcgccg aaaccattaa
     6001 cccggcgcat ccaggctcgc acttttcagg cggcaatctg gaaacgctaa gcgataagcc
     6061 gggcaatccg gtgcaacagg cgttgatcgc ttttcatgaa aaatactatt catctaatct
     6121 gatgaaggcg gtgatttaca gtaataaacc cttgccggaa ctggcgagta ttgccgccgc
     6181 aacctatggt cgcgtgccga ataaacagat taaaaaaccg gaaattaccg tacctgtcat
     6241 caccgaggcg cagaagggca tcattattca ttacgtgccg gcgctaccgc gtaaagtgct
     6301 gcgcgtggag tttcgtattg ataacaatag cgcgcagttc cgtagcaaga ccgatgaact
     6361 ggtctcttat ctgattggca atcgtagccc ggggacgctc tctgactggc tgcaaaaaca
     6421 aggactggtc gaaggtatta gcgcggattc tgatccgatt gttaatggta acagcggcgt
     6481 atttgccatt tcggcaacgc tgactgataa aggtttggcc aatcgtgatg aagtcgtcgc
     6541 agctatcttt agctatctca atacgttacg tgaaaaaggg atagataaac gttactttga
     6601 cgagctggcg catgtgctgg atctcgactt ccgctatccg tcgattaccc gcgatatgga
     6661 ctatgtcgag tggctggcgg acactatgat ccgcgtcccg gtagcgcata cgctggatgc
     6721 ggcgaatatc gccgatcgtt acgatcctgc cgctatcaaa aatcgcctgg cgatgatgac
     6781 gccgcagaat gcgcgcatct ggtacatcag tccccaggaa ccccataata agattgcgta
     6841 ttttgtggat gcgccttatc aggtcgataa gattagcgaa cagacgttta aaaactggca
     6901 gcaaaaagca cagggcattg cgttgtcgct gccggagtta aacccctata ttcctgatga
     6961 ttttacgctt attaagaatg acaaaaacta cgtgcggcca gaactgattg tcgataaagc
     7021 ggatttgcgc gtggtttatg cgccgagtcg ttatttcgcc agcgagccaa aagctgacgt
     7081 gagtgtggta ttgcgtaacc cgcaggcgat ggacagcgcc cgcaatcagg tactgttcgc
     7141 ccttaatgat tatctggcgg gaatggcgct agatcagctc agcaaccagg cggcagtggg
     7201 cggcattagc ttttccacta acgccaacaa tggtctgatg gtcactgcga acggttatac
     7261 ccagcgtttg ccgcagcttt tcctagcgct gctggaagga tattttagct acgacgccac
     7321 ggaagaacag ctggcgcagg cgaaatcctg gtatacgcag atgatggatt ctgcggagaa
     7381 gggaaaagcc tacgaacagg cgattatgcc ggtgcagatg atttcgcagg tgccttattt
     7441 ttcccgtgat gaacgtcgcg ctttgctgcc gtccattacg ttaaaagagg tgatggccta
     7501 tcgtaatgcg ttaaaaacgg gcgctcgtcc ggaatttctg gttataggaa atatgagcga
     7561 agcccaggcg acctctctgg cgcaagatgt ccaaaaacag ctcgcggcga acggatcggc
     7621 gtggtgtcgt aacaaagacg tggtggttga gaaaaagcag tccgtaatat ttgaaaaagc
     7681 gggcagtagc accgactccg cgttagccgc ggtctttgtc ccggtcggct acgacgagta
     7741 cgtcagcgcc gcctacagcg cgatgttagg tcagattgtt caaccgtggt tttacaatca
     7801 gctacgaacc gaagagcaac tgggatacgc tgttttcgcc tttccgatga gcgttggccg
     7861 tcagtgggga atgggattcc tgctacagag caacgataaa cagccctctt acctgtggca
     7921 acgctatcag gcatttttcc ctgacgccga ggcgaagctg agggcgatga agccggaaga
     7981 gttcgcccaa attcagcagg cgatcattac gcaaatgcgc caggcgccgc aaacgttggg
     8041 cgaagaagca tcccgtttaa gcaaggattt cgatcggggt aatatgcgct ttgactcgcg
     8101 tgataaaatc atcgctcaga taaaattgct gacgccacaa aagcttgccg atttcttcca
     8161 ccaggcggtg gtggaaccac aaggtatggc aatattgtca cagattgccg gtagccagaa
     8221 tggaaaagca gaatacgtgc atccgacagg ctggaaagtg tgggataacg tcagcgcttt
     8281 gcagcaaacg ttacctctaa tgagcgaaaa gaatgaatga tgtcgccgag actcttgatc
     8341 ctctgcgctt gccccttaca ggcgagcgtt tgattgaagc atcagcgggc acaggcaaaa
     8401 cgtttactat cgcggcgctg tatctgcggc tactgctcgg tttaggcggc agcgccgcat
     8461 ttccccgtcc gttgaccgtt gaagaactgc tggtggtaac ctttacggag gccgccactg
     8521 aagagctgcg tgggcgaatc cgcagtaata tccatgagtt gcgcatcgcc tgtctgcggg
     8581 aaagcacgga taatccgctg tatgcccgct tgctggaaga aattagcgac aaaaagcagg
     8641 ccgcgcagtg gttattactg gcagaacgac aaatggacga ggccgcggtt tttaccatcc
     8701 acggtttttg ccagcgtatg ctcagcctga acgctttcga atccggtatg ttgtttgagc
     8761 aacagcttat tgaagacgaa tctttgttgc gttatcaggc ctgcgccgat ttctggcggc
     8821 gtcattgcta tccgctgccg cgcgacatcg cgcaggtggt gtttgacgtg tggaaggggc
     8881 cgaaggcgct cttaaaagat atcgatcgtt atctgcaggg cgaagcgccg gtcattaaag
     8941 cgccgccatc gcaggaggag acgctggcat cgcgccatga acagatcctg gcgcgcatca
     9001 accaggtgaa gcagcagtgg tgtgaggcgg ttagcgagct ggacgcgctg atcgaatcat
     9061 ccggcatcga tcgcagaaaa ttcaaccgcg gcaatcaggc gaaatggatc gaaaagatca
     9121 ccgcgtgggc gcaagaagag accaaaaatt atcaattacc cgaggcgttg ggaaaatttt
     9181 cacagcgttt tttagctgag cgcaccaaag ctgggggcgt gacgccccag cacccattgt
     9241 ttgtcgccat tgataacctg ttgggcgaac cgctatcgat taaagatctg gttcttaccc
     9301 gagcgctctc agagatccgt gaaacggtgg ctcaggaaaa acgacggcgc ggcgagctgg
     9361 ggtttgacga tatgctcagc cgtttagata ccgcgctgcg tagtgaaagc ggcgaggcgc
     9421 tggctgcggc gattcgtacc cgttttccgg tggcgatgat cgatgaattt caggataccg
     9481 acccacaaca gtaccgtatt tttcgccgta tctggcgaca tcaacccgat acggcgctat
     9541 tgctgattgg cgatcctaaa caggcgattt atgcgtttcg tggcgcggat atctttacct
     9601 acatgaaggc tcgcagcgaa gtgagcgcgc actataccct tgacactaac tggcgctccg
     9661 cgccggggat ggtgaatagc gttaacaagc tgttcagtca gatgaatgac gcctttatgt
     9721 tccgcgatat tcccttcagt ccggtaaagt ttgcgcccag aaaccagtcg ctgcaattta
     9781 aagtgaatga cgcgcctcaa ccggcgatga ccctgtggct aatggagggg gaaagctgcg
     9841 gttcgggcga ttatcaaagt tatatggcgc aggtgtgcgc cacgcaaatt cgcgactggc
     9901 tgcgtgccgg gcaaacgggc gacgcgctgc tgacgaacgg cgattcgtcg cggcccgttc
     9961 gcgcctcgga tattagcgtg ctggtgcgca gcaggcggga agccgcgctg atacgggatg
    10021 cgctgacctt actggcgatc ccctccgtct atctttctaa ccgcgacagc gtattcgaaa
    10081 cgctcgaagc gcaggaaatg ctgtgggtgt tgcaggcggt gatggcgccc gaacgtgaga
    10141 atacgctgcg tagcgctctg gcgacatcaa tgatgggcct taccgcgctg gatatcgaaa
    10201 cgcttaacaa tgatgaaaat gcgtgggatg cggttgttga agagtttgat ggctaccgac
    10261 agatttggca taaacgcggc gtgatgccta tgctgcgcgc gctaatgtcg gcgcgcaata
    10321 ttgctgaaaa cctgctggcg acggcgggag gtgaacgtcg gctgacggat attctgcata
    10381 ttagcgaact gttacaggaa gccggttcgc agctggaaag cgaacatgcg ctggtgcgtt
    10441 ggctggcgca acatatcctt gaacctgata gcaatgcttc cagccagcaa ctacgtctgg
    10501 aaagcgataa gcatctggtg caaatcgtca ccattcataa atcgaaaggt ctggaatacc
    10561 cgctggtctg gttacctttt atcacccatt tccgcgtgca ggaccaggct ttttatcacg
    10621 acaggcactc ctacgaggcg gtgctggacc ttagtcacgc cgaagagagc atagcactgg
    10681 cggaagccga acgcctggcg gaagacctgc gcctacttta tgtcgcgctg acccgtgcag
    10741 tgtggcattg cagcctcggc gtcgcgccgc tggtgcggcg tcgtagcgat aagaaaggcg
    10801 agacggatgt gcaccaaagc gcgcttgggc gactcctgca aaaaggcgaa ccgatggatg
    10861 ccgcaggcct tcgcgcctgt attgaggcgc tatgcgacga ggatatcgtg tgtcgaacgc
    10921 caggcaatac ggataacgac cgctggcaaa ttgccgctgc atcgcacgcg gaactcagcg
    10981 ccagaacgct gcaacgcctg ctttatgata gctggcgcgt caccagttat tccggtttgc
    11041 agcagcgggg acatagcgtg gcgcaagatc ttattcctcg tctcgacatt gacgccgcag
    11101 gcgttggcga agcggcggaa gcgccggcaa tgacgccgca tcactttcct cgcggggcat
    11161 cgccgggaac atttttgcac agcctgtttg aagagcttga ttttactcaa ccgatagacc
    11221 cccaatgggt acaggaaaaa ctggagctga gtggttttga aacgcgatgg gagcccgtac
    11281 ttacccgctg gctggacacc gtgttgcacg ttccccttaa cgagacgggc gttagtctga
    11341 gcgtgctgac cgagcgtgaa aaacaggttg aaatggagtt ttatctgccg attgcccagc
    11401 cgcttaccgc cggagagtta gatgcgttga ttcgtcgata cgacccgctt tcagcaggtt
    11461 gccctgcgct ggatttcatg caggttcgcg gcatgttaaa gggctttatc gacctggtgt
    11521 tccgttatga ggggcgctat tacctgctcg actataaatc taactggctg ggcgaggata
    11581 gcgccgctta tacccagacg gcgatggctg cggcgatgca ggcgcatcgc tatgatttgc
    11641 agtaccagct ttatacgctg gcattgcatc gttaccttcg tcatcgaatg gcgaattacg
    11701 actatgaacg ccatttcggc ggcgtcatct atctcttttt acgcggggtg gatagcgaac
    11761 gtccgcagca gggtattttt accactcgtc ctgcggcggc gttaattaac caactggatg
    11821 atatgtttgc aggtgaaatg agtgaggagg cgcaatgaca atccagaagc ggttgctgga
    11881 ggccgttgaa caaaaactct tacggcccat tgatgcccag tttgctttaa ccgtcgccgg
    11941 taacgacgat cccgccgtga cgctggcggc agcgctgctt agtcatgacg caggtgaagg
    12001 tcacgtgtgt ctgccgttgt cgcgtttaac gttaacggag gaggcgcatc ccttactggt
    12061 cgcctggata agcgaaacgg ctacgccaat cgactggaaa aagcggttac tggcgtctgc
    12121 ggcggttagc tgcggcgata gccccgcgcc gttaattctg tgcggcgatc gcctctacct
    12181 gaatcgcatg tggtgcaacg agcgtacggt tgcgcgcttt tttaacgagg ttaaccaggc
    12241 catcgccgta gatgaagatc agttatcccg tattctggac gcgctattcc ctccgacaga
    12301 cgaggtgaac tggcaaaagg tggccgccgc cgtagcgcta actcgccgta tctccgtgat
    12361 ttcaggcggt cccggcaccg gtaaaaccac caccgtcgcg aagctgctgg cggcattaat
    12421 tcaaatggcg gatggcgaac gttgccgtat ccggctggcg gcgccaaccg ggaaagcggc
    12481 cgcacgcctg acggagtcgc tcggcgcggc gttgcgtcag cttcctctta ccgatgcgca
    12541 gaaaaagcgt ataccggagg acgccagtac gctgcaccga ctgctgggcg cacagcccgg
    12601 cagccagcga ttacgccatc atgcgggcaa cccgctgcat ctggacgtgc tggtggtcga
    12661 tgaggcatca atgattgatt tgccgatgat gtcacgtttg attgacgctc tgccgccgca
    12721 cgggcgggtc atttttcttg gcgatcgcga tcagttggca tccgttgagg cgggcgctgt
    12781 gttgggcgat atttgcgcct atgtcaacgc agggtttacg gcggaacgcg cccgacagct
    12841 aagtcgactc actggtagcg ccattccggc gggggccgga acgcaagccg cgtctttacg
    12901 cgatagcctc tgtttgttgc aaaagagcta ccgtttcggc agcgattctg gcatcggcaa
    12961 gctggcggcg gcaattaact gtggcgacag gtcggcaatc caggctgttt ttcagcaggg
    13021 gtttagcgat atagagaagc gtacattgca aagcagcgac gattatgccg ggatgctgga
    13081 tgaagcgctg gcgggctatg ggcgctacct gcggttgctg catgaaaaag cggcgccgga
    13141 ggcaatcctt caggctttca atgagtatca actgctttgt gcgctgcgcg aaggcccatt
    13201 tggcgtgagg ggactgaatg accgcattga gcaggcgatg gtgcagcaac gaaaaattca
    13261 gcggcatccg cactctcgct ggtatgaagg gcgtccggta atgattgcgc gcaacgatag
    13321 cgcgttgggg ctatttaacg gcgatattgg tattgcgctc gatcgcgggc aggggttacg
    13381 cgtctggttt gtgatgccgg acggcacgat caagtccgtt cagcccagcc gtctgccgga
    13441 acatgataca acctgggcga tgacggtaca taaatcacag gggtctgaat ttgatcacgc
    13501 cgcgctgatt ttacccagcc aacgttcgcc ggtcgtgacg cgggagctgg tgtataccgc
    13561 tgttacgcgg gcgcggcggc ggttatcgct gtatgccgat gaacggatcc tggcaggcgc
    13621 gattgtgacg cgaacggaac ggcgcagcgg gttagccacc ttatttgatg aagtcagtcg
    13681 tatcggataa gacgagttct cgccggatgg cgacgcgtag cgtcttatcc ggcctccaaa
    13741 tgatgctttc gagcgtaggc ctgataagcg cagcgccatc aggcccccct tgttatccta
    13801 aatctgccat cagcaccttt gaacgtcgct gatagttata catttttttc ttgctctcag
    13861 gcagtaactc aatatcgaca ggcgtaaaac cgcgctcctg gaaccagtga atactgcgcg
    13921 tcgtcaacac aaacaattta cgcagcccca tttgccgtgc ctgggcggca acccgctcca
    13981 gaagcacttc tccacgcgat gagctgcgat aatccggatg taccgctacg caggccattt
    14041 cgcctatttt ctcttccaca aaaggataca gcgccgcgca agcgatagtc atattatcgc
    14101 gctgaataat ggtaaattta tcgatctcca tctccagttg ttcacgggaa cggcgtacca
    14161 gaatgccctg ctgttccagt gggcggataa gctccagaat accgccaata tcgttgatgg
    14221 tagcgcggcg gatctgctcg gcgctctcca tgacgatctg cgtaccgata ccatcacgcg
    14281 agaacaattc ctgtaatagc gagccatctt cctgatagct gatcagatgg caacgacgaa
    14341 cgccgctacg acaggctttt accgcgccgc gcaaaaaacg tacggttccg gagttgtaat
    14401 cgccctgcgc ttccaactct tccacccgcg cctgcgcttc attcgggaag agttcagaaa
    14461 tgatgccgcc ctcgctattg gtaacgccct gagaagaaca gaaaccgatc attttttccg
    14521 ctttcagttt aacggcgagt tgagtggcaa tctcttctga ggtcagatta aaactttcgc
    14581 cggtcactga gacggcgacc ggccccatca gaacgatcgc gccgttatcc aactggcggt
    14641 tgatcgcatc ttcatcaatg cgccggatac ggccgctatg acagtagtcc acgccatcat
    14701 caacgcccag cggctgcgca atggtgaaat tgccgctgac gacattaatg tgcgcgccct
    14761 gcaacggcgt attgttcaga ctcatcgaca gacgggcggt aatatcaagc tggagtaaac
    14821 cggcggcctg tttcaccagc tccagtgttt tggcgtccgt cacccgtgtg tttttgtggt
    14881 aaatcggttc atgatgatgc gcggccagat tggcgtcgat ttgcggtcgc gcgccataca
    14941 ccacgacaag gcgaataccg aggctatgca gtagcccgat atcgctaacg atgctggaaa
    15001 aattgtcatg ctcaatggct tcgccgccga gcataatgac aaaggttttt ccgcgatggg
    15061 tattgatata gggaactgaa tggcgaaacc cttctaccag ttcggtttta cgttccttta
    15121 tcattgcgcg ccccactagt gaattattat tcgaaattag tgtattttta ttctgttttt
    15181 gccctctgtg caagcgtaaa ttttatgcgg tccgatcgct tttcttagta atgccgtgaa
    15241 tataaaaaga atgtttaccc ttttatagat gacagattat gcgtcattcg ctaaagtttc
    15301 cggtcaattt ggatgaactt tgtatgatct ctatttagtt tttgctcggg agaagcatgt
    15361 cgggagccaa ttcagcaatc agccgtcgcc gtttactaca aggcgcgggc gccatgtggc
    15421 tattaagcgt gagccaggtc gggctggctg ccgtaagcca ggtcgttgcg gtgcgtatct
    15481 ggcctgcgtc cagctatacc cgcgtcacgg tagagtcgaa tcgtctgctg aaatataaac
    15541 aatttgcctt aagtaacccg gaccgcgtgg tggtagatat tgaggatgtg aatctgaact
    15601 cggtgcttaa aggcattggc gcgcagattc gcagcgacga tccgtatatc aaatccgcaa
    15661 gggtagggca gtttgatcct aagactgtgc gtatggtctt tgagctaaaa caaaacgtga
    15721 agccgcagct atttgcgctg gcgcctgtgg caggctttaa agaacgtctg gtgatagatc
    15781 tttatcctgc taatgcgcag gatatgcagg atccgctgct ggcgctgctg gaagactaca
    15841 ataaaggcga tctggataaa caggtgccgc cttcgcaaag cgggccgcag cccggtaaag
    15901 cggggcgcga tcgtcccatt gtcattatgc ttgatccggg acacggcggc gaagaccctg
    15961 gcgcgatagg caaatacaaa acgcgtgaaa aagacgtggt gctccagata gcccgccgcc
    16021 tgcgcgcgtt gatcgaaaaa gaaggcaaca tgaaggtcta tatgacgcgc aatgaagaca
    16081 tcttcattcc gttaaaagtc cgggtggcga aagcgcagaa acagcgcgcc gacctgtttg
    16141 tctctattca tgcggatgcc ttcaccagcc ggcagcctag cggttcatcc gtattcgcgc
    16201 tatcgactaa aggcgccacc agtactgcgg cgaaatatct ggcgcaaacg cagaacgcct
    16261 cggacttaat tggcggcgtg agcaaaagcg gtgaccgtta tgtcgaccat acgatgttcg
    16321 atatggtgca atcgctgacc attgccgata gtttgaaatt cggtaaagcg gtgttgaagc
    16381 agcttggtaa aattaatgac ctgcataaaa acaaggtcga gcaggcgggg tttgcggtgt
    16441 taaaggcgcc cgatattccg tctattctgg tcgagacggc gtttatcagt aacattgaag
    16501 aagaacgcaa gctcaagacc gcgacgttcc agcaacaggt cgcagagtcg attctggcgg
    16561 gcattaaagc ctattttgcc gatggggcga cgctggcgag aagaagttaa cctgagatga
    16621 cggcgagttt attgcgcggg taagtaggat gctgcccgca ctgtcgttgc ggaccagatg
    16681 acagatacaa aaaaacaccc gtaagggtgt tcattaagtt ggttgcgggg gccggatttg
    16741 aaccgacgac cttcgggtta tgagcccgac gagctaccag gctgctccac cccgcgtccg
    16801 tctaaacttg cattctcatt gtaattggtt gcgggggccg gatttgaacc gacgaccttc
    16861 gggttatgag cccgacgagc taccaggctg ctccaccccg cgtccgtgga tgcgcactat
    16921 actccgctga gcttttgttg caaccctttt ttcatataaa tcgctaattt ctcatgaatt
    16981 gcgcaaatac accgcagata gcgcgatttt taaacgaatt tacataatga gatcgcgatc
    17041 gcatttcatt acttcggacg gtttgttatc ttcaccgggc actttcgatt acgcagaaga
    17101 cgagacacca tgaaaggacg ttgggcaaaa tatgtggcga caggcgtaat gctggcaatg
    17161 ctggctgcct gttcatcaaa accgaccgat cgcggtcagc aatataagga cgggaaattt
    17221 acccagccct tctccctggt aaaccagccg gacgcggtgg gcgcgccgat taatgctggt
    17281 gactttgccg agcaggtcga ccagatccgt tccgcgtcgc cgcgtttata caccaatcaa
    17341 agcaacgtct ataacgctgt ccagaactgg ttacgttccg gaggcgatac gcgcactatg
    17401 cgtcagtttg gtatcgatgc ctggcagatg gaaggcaccg acaactacgg taacgtccag
    17461 ttcacgggct actatacgcc cgtcgttcag gctcgccata cgcgccaggg cgcgttccag
    17521 taccctatct atagtatgcc gccaaaacgc ggacgcttac cgtcccgcgc ccagatctac
    17581 gcaggcgcgc tgagcgataa gtacatcctg gcctggagta attcgctgat ggataacttt
    17641 attatggatg tccagggcag cggttatatt gatttcggtg atggtagtcc gctgaacttc
    17701 tttagttatg ccggtaaaaa tggctggcct tatcgcagta ttggtaaagt gcttatcgat
    17761 cgcggtgaag tgaaaaaaga agatatgtcg atgcaggcta tacgcgaatg gggagagaag
    17821 cacagcgaag cggaagtgcg tgaattactg gagcagaacc cgtcgttcgt cttctttaaa
    17881 ccgcaatctt ttgcgccggt caaaggcgcc agcgctgtac cgctgattgg gcgagcatcc
    17941 gtcgcctccg accgcagcat cattccgccg ggcacaacct tgttggcgga agtaccgttg
    18001 ctggataaca acggtaaatt tagcggtcag tatgagctac gtttgatggt cgcactggat
    18061 gtcggcggag cgattaaagg ccagcacttt gatatttacc aggggattgg cccggatgcc
    18121 gggcatcgtg ccggatggta taatcactat ggtcgcgtct gggtgttaaa aagcgcgccg
    18181 ggcgccggta acgtgtttag cggctgattg tggtattctg cgacaaccgg attgcccgat
    18241 aacgcgattg ctatcgggcc tgaaaatagt gagcaggggt gaggaataac ctcacctttt
    18301 ttattctgag gtcatatgtc agtggtgata agtgatgcct ggcgccaacg ctttggcggc
    18361 accgcgcgtc tgtacggtga aaaagcgctg cagcggtttg ctgaggcgca tatctgcgtc
    18421 gtgggaatcg gcggggtagg atcatgggcg gcagaggcgc tggcgcgtac gggcatcggc
    18481 gcgattacgc tgattgatat ggacgatgtc tgcgtgacca atacgaaccg tcagatccat
    18541 gcgttgcgtg ataacgttgg gttggcgaaa gcggaagtga tggccgaacg gattcggcaa
    18601 attaacccgg agtgccgggt aacggttatc gatgatttca tcacgccgga taatgtggcg
    18661 ggttatatgg acgcgggttt tacctatgtc attgacgcca ttgacagcgt tcgtccaaaa
    18721 gccgcgctga ttgcgtactg tcgccgatat aaggttcctt tagtaaccac tggcggcgcg
    18781 ggcgggcaga tcgatccgac gcaaatccag gtcgctgatt tggcgaaaac tatccaggat
    18841 ccgctggcgg caaaactgcg tgagagattg aaacataatt ttggcgtagt gaagaacagt
    18901 aaaggtaagc tgggcgtgga ctgcgttttt tccaccgaag cgctggttta cccacaggcg
    18961 gacggttccg tatgcgcgat gaaagctacc gcagaagggc caaaacggat ggattgcgcc
    19021 tctggcttcg gcgcggcgac gatggtaacg gcaacgttcg gttttgtcgc cgtttcccat
    19081 gcgctgaaga agatcatggc taaagcggcg cgacaagaat aaaaggacgg ggcggagtgt
    19141 cacgcagacg cgtatccggc cctgcgccct ttgttagcga aagaagcgct gtaccctgcc
    19201 gaacaccggt ttcagacggg cgcggagata atgggaatat aaattttcag atatgcatag
    19261 aaacagcccg aaccatactg cacaaaagca gagcagttcc gcgtaattaa tgtgctcgcc
    19321 aaatatcata atggcaagta agaactgtaa agacggctct atatattgcg ccagtccggt
    19381 gacaatcaac gaggtgtgat ttaacgcgat ggcaaataat accagtggaa tgatcgtcac
    19441 tggcgccgtc atgacataca aaaagaaagg agtattagcg gatataattg gtccagtatc
    19501 gctaaagaga aaaattaata gtgagacagg caatgcccat aatgtttcaa tcgttatcga
    19561 tgtcatcaca tcataatgta taaactttcg cgccaggcca tatagcgcaa atgataatcc
    19621 catggttagc gccagcgccg ggaaatgccg tagcatgata atttgaaaag tcaggccaca
    19681 gacaccagaa aaaacggcga tggcctgaaa caacgacagt ttttctttaa gaaaaatgca
    19741 tcccagcgca ataacaaata gcgggttgat aaaatagccg aggctggcat caagtaccag
    19801 atgatgggtt agcgcataaa tgaaagatga ccatgagaca atcatcaaaa gtccggcgat
    19861 catgcagaag aaaaaggatt ttttatcttt ccaggcatca tgaaatcgcg ttcgctgccg
    19921 aaataacaac cttactgcca gtaataatgg aattgaccag aacacccggt atatcaatat
    19981 ttgtgcgaga tttccccctg ataaatattg ataatataaa ggtgttaacc cccataatat
//
LOCUS       DAJVBX010000072        19953 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.072, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000072 DAJVBX010000000
VERSION     DAJVBX010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 19953)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19953)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19953
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.072"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..319
                     /locus_tag="OPV72_002201"
     CDS             <1..319
                     /locus_tag="OPV72_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914486.1"
                     /translation="SHSQGRCAEFTRKAIQAGGITLGHTYHAKDYGPMLRSAGFTAIG
                     TYEMPREGDVIIIQPYAGGNPSGHMAIYDGAEWYSDFKQRDMWAGPGYRAARPSYTIY
                     RKN"
     gene            319..837
                     /locus_tag="OPV72_002202"
     CDS             319..837
                     /locus_tag="OPV72_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbjP/YqhG family protein"
                     /protein_id="HCR9914487.1"
                     /translation="MKTFSLVALILLLCSCSAPHHDSTQAVKQFYTSWMTTFMNDVNT
                     PDDTTALMQRYVAKEVIHRLALIQSLYEQEIVGADYFMYAQDYAPEWIPQLRVGKAHP
                     FLGGEKVDVLLATESTPIHLEVYTRWEEGRWKIYRVRDADKDYEQPIYDAGAITQAEA
                     WSAKVAPEYEKH"
     gene            complement(904..1560)
                     /locus_tag="OPV72_002203"
     CDS             complement(904..1560)
                     /locus_tag="OPV72_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HCR9914488.1"
                     /translation="MPTNTLDKIRHSLSCVAVLFGLFGIFVFASFSPSYAWLYLGGLA
                     APFIYSIVFVYAIAAWSIYSKYYPFLSLGRLSFVECFVPALALVCLTVLYNVFSGPEP
                     WMAELSRQFFLHKFLNTLVMCFLAPVAEEIIFRGFLLNSSIGWGRYSRVSGIIITSLA
                     FAFMHTQYLFAVTFVYLFVFSSILCVVRMRSRGLMIPITLHILNNAWVIFGLLFSATE
                     "
     gene            complement(1658..2872)
                     /gene="fabB"
                     /locus_tag="OPV72_002204"
     CDS             complement(1658..2872)
                     /gene="fabB"
                     /locus_tag="OPV72_002204"
                     /EC_number="2.3.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase I"
                     /protein_id="HCR9914489.1"
                     /translation="MKRAVITGLGIVSSIGNNQQEVLASLREGRSGITFSQELKDAGM
                     RSQVWGNVKLDTTGLIDRKVVRFMSDASIYAYLSMEQAVADAGLAPEVYQNNPRVGLI
                     AGSGGGSPKFQVFGADAMRSPRGLKAVGPYVVTKAMASGVSACLATPFKIYGVNYSIS
                     SACATSAHCIGNAVEQIQLGKQDIVFAGGGEELCWEMACEFDAMGALSTKYNDTPEKA
                     SRTYDAHRDGFVIAGGGGMVVVEELEHALARGAHIYAEIVGYGATSDGADMVAPSGEG
                     AVRCMQMAMHGVDTPIDYLNSHGTSTPVGDVKELGAIREVFGDNSPAISATKAMTGHS
                     LGAAGVQEAIYSLLMLEHGFIAPSINIEELDEQAAGLNIVTETTERELTTVMSNSFGF
                     GGTNATLVMRKL"
     gene            3032..5032
                     /gene="mnmC"
                     /locus_tag="OPV72_002205"
     CDS             3032..5032
                     /gene="mnmC"
                     /locus_tag="OPV72_002205"
                     /EC_number="1.5.-.-"
                     /EC_number="2.1.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416827.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tRNA
                     (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase
                     MnmD/FAD-dependent
                     5-carboxymethylaminomethyl-2-thiouridine(34)
                     oxidoreductase MnmC"
                     /protein_id="HCR9914490.1"
                     /translation="MKQYAIQPATLEFNAEGTPVSRDFDDVYFSNDNGLEETRYVFLG
                     GNRLAERFPVHSHPLFIVAESGFGTGLNFLTLWQAFDSFRSAHPQATLQRLHFISFEK
                     FPLTRDDLALAHQHWPELAPWAEQLQAQWPLPLPGCHRLLLDRGRVTLDLWFGDINEL
                     TDQLDATLNQTVDAWFLDGFAPAKNPDMWTPNLFNAMARLARPGATLATFTSAGFVRR
                     GLQEAGFTMQKHKGFGRKREMLCGVMEQHLMPTLSAPWFYCSGSEKRETAIIGGGIAS
                     ALLSLALLRRGWQVTLYCADDQPAQGASGNRQGALYPLLSKHDAAINRFFPTAFTFAR
                     RLYDALPVSFDHAWCGVTQLGWDEKSQQKIAQMLSLALPAGLASALNAEEAEQAVGVT
                     TRCGGITYPAGGWLCPEQLTRAVIALATEQGLQTRFRHTLTSLVAQESRWQLRFTSGE
                     TASHETVVLANGHQINRFDQTRPLPVYAVGGQVSHIPTTPALSALRQVLCYDGYLTPQ
                     NPHNQQHCIGASYHRGDESTVWREEDQRQNRQRLLDCFPDANWATEVDVSGNSARCGV
                     RCATRDHLPMVGNVPDYHATLTHYADLADNKTSAASAPVYPGLFMLGALGSRGLCSAP
                     LCAEILAAQMSNEPIPLDAGTLAALNPNRLWVRKLLKGKAVK"
     gene            complement(5084..5359)
                     /locus_tag="OPV72_002206"
     CDS             complement(5084..5359)
                     /locus_tag="OPV72_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcL family protein"
                     /protein_id="HCR9914491.1"
                     /translation="MIAEFESRILALIDDMVEHASDDELFASGYLRGHLTLAIAELES
                     GDDHSVEAVYANVSQSLEKAIGAGELSPRDQALVKAMWDNLFDKAKQ"
     gene            complement(5392..5941)
                     /locus_tag="OPV72_002207"
                     /pseudo
     CDS             complement(5392..5941)
                     /locus_tag="OPV72_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461323.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P hydroxylase"
     gene            complement(5941..6750)
                     /locus_tag="OPV72_002208"
     CDS             complement(5941..6750)
                     /locus_tag="OPV72_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HCR9914492.1"
                     /translation="MDNFYDLFMVSPLLLVVLFFVAVLAGFIDSIAGGGGLLTIPALM
                     AAGMSPANALATNKLQACGGSLSSSLYFIRRKVVNLAEQKLNILMTFIGSMSGALLVQ
                     HVQADILRQILPILVIFIGLYFLLMPKLGEEDRQRRLYGLPFALIAGGCVGFYDGFFG
                     PAAGSFYALAFVTLCGYNLAKSTAHAKVLNATSNVGGLLLFIIGGKVIWATGFVMLVG
                     QFLGARMGSRLVLSKGQKLIRPMIVIVSAVMSARLLYDSHGQEILHWLGMN"
     gene            complement(6750..7574)
                     /gene="mepA"
                     /locus_tag="OPV72_002209"
     CDS             complement(6750..7574)
                     /gene="mepA"
                     /locus_tag="OPV72_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-insensitive murein endopeptidase"
                     /protein_id="HCR9914493.1"
                     /translation="MKKTAIALLAWFVSSASLAATPWQKITHPVPGAAQSIGSFANGC
                     IIGADTLPVQSDNYQVMRTDQRRYFGHPDLVMFIQRLSHQAQQRGLGTVLIGDMGMPA
                     GGRFNGGHASHQTGLDVDIFLQLPKTRWSQAQLLRPQALDLVSRDGKHVVPSRWSSDI
                     ASLIKLAAQDNDVTRIFVNPAIKQQLCLDAGSDRDWLRKVRPWFQHRAHMHVRLRCPA
                     DSLECEDQPLPPPGDGCGAELQSWFEPPKPGTTKPEKKTPPPLPPSCQALLDEHVL"
     gene            complement(7578..8663)
                     /gene="aroC"
                     /locus_tag="OPV72_002210"
     CDS             complement(7578..8663)
                     /gene="aroC"
                     /locus_tag="OPV72_002210"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HCR9914494.1"
                     /translation="MAGNTIGQLFRVTTFGESHGLALGGIVDGVPPGIPLTEADLQHD
                     LDRRRPGTSRYTTQRREPDQVKILSGVFDGVTTGTSIGLLIENTDQRSQDYSAIKDVF
                     RPGHADYTYEQKYGLRDYRGGGRSSARETAMRVAAGAIAKKYLAEKFGIEIRGCLTQM
                     GDIPLEIKDWRQVELNPFFCPDADKLDALDELMRALKKEGDSIGAKVTVMASGVPAGL
                     GEPVFDRLDADIAHALMSINAVKGVEIGEGFNVVALRGSQNRDEITAQGFQSNHAGGI
                     LGGISSGQHIVAHMALKPTSSITVPGRTINRMGEEVEMITKGRHDPCVGIRAVPIAEA
                     MLAIVLMDHLLRHRAQNADVKTEIPRW"
     gene            complement(8699..9631)
                     /gene="prmB"
                     /locus_tag="OPV72_002211"
     CDS             complement(8699..9631)
                     /gene="prmB"
                     /locus_tag="OPV72_002211"
                     /EC_number="2.1.1.298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3 N(5)-glutamine
                     methyltransferase"
                     /protein_id="HCR9914495.1"
                     /translation="MDKIFVDEAVSELHTIQDMLRWAVSRFSAANIWYGHGTDNPWDE
                     AVQLVLPSLYLPLDIPEDMRTARLTSSEKHRIVERVIRRINERIPVAYLTNKAWFCGH
                     EFYVDERVLVPRSPIGELINNHFAGLISQQPKYILDMCTGSGCIAIACAYAFPDAEVD
                     AVDISPDALAVAEHNIEEHGLIHHVTPIRSDLFRDLPKVQYDLIVTNPPYVDAEDMSD
                     LPNEYRHEPELGLASGTDGLKLTRRILGNAPDYLSDDGVLICEVGNSMVHLMEQYPDV
                     PFTWLEFDNGGDGVFMLTKAQLLAAREHFNIYKD"
     gene            9797..10348
                     /gene="smrB"
                     /locus_tag="OPV72_002212"
     CDS             9797..10348
                     /gene="smrB"
                     /locus_tag="OPV72_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease SmrB"
                     /protein_id="HCR9914496.1"
                     /translation="MKKKTSLSEEDQALFRQLMVGTRKIKQDTIVHRPLRKKITEVPT
                     RRLIQEQADASHYFSDEFQPLLNTEGPVKYVREDVSHFELKKMRRGDYSPELFLDLHG
                     LTQLQAKQELGALIAACRREHIFCACVMHGHGKHILKQQTPLWLAQHPHVMAFHQAPK
                     EYGGDAALLVLIEVEEWQPPELP"
     gene            complement(10397..10882)
                     /gene="sixA"
                     /locus_tag="OPV72_002213"
     CDS             complement(10397..10882)
                     /gene="sixA"
                     /locus_tag="OPV72_002213"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohistidine phosphatase SixA"
                     /protein_id="HCR9914497.1"
                     /translation="MQVFIMRHGDAALDAASDSVRPLTSCGCDESRLMANWLKGQKVD
                     IERVLVSPFLRAEQTLDVVGDCMNLPTQVDVLPELTPCGDVGLVSAYLQALANEEIGS
                     VLVISHLPLVGYLVSELCPGETPPMFTTSAIANVTLDESGKGTFNWQMSPCNLKMAKA
                     I"
     gene            complement(11091..13238)
                     /gene="fadJ"
                     /locus_tag="OPV72_002214"
     CDS             complement(11091..13238)
                     /gene="fadJ"
                     /locus_tag="OPV72_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid oxidation complex subunit alpha FadJ"
                     /protein_id="HCR9914498.1"
                     /translation="MTTTSAFMLSVRLDNVAVVAIDVPGEKVNTLKAEFAAQVRAILK
                     QIRENKALQGVVFISAKADNFIAGADINMIGHCQNAQEAETLARQGQQLMAEIQALPV
                     PVIAAIHGACLGGGLEMALACHRRICTDDVKTVLGLPEVQLGLLPGSGGTQRLPRLVG
                     VSTALDMILTGKQLRARQALKAGLVDDVVPQTILLEAAVELAKKERLAQRTLPVRERI
                     LAGPLGRALLFRLVRKKTAQKTQGNYPATERIIDVIETGLAQGSSSGYDAEARAFGEL
                     AMTPQSQALRAVFFASTEVKKDPGSDAPPGPLNSVGILGGGLMGGGIAWVTACKGGLP
                     VRIKDINTQGINHALKYSWDLLETKVRRRHIKASERDKQLALISGSTDYRGFSHRDLV
                     IEAVFEDLPLKQQMVAEVEQNCATHTIFASNTSSLPIGDIAANAARPEQVIGLHFFSP
                     VEKMPLVEVIPHASTSAQTIATTVKLAKKQGKTPIVVSDKAGFYVNRILAPYINEAIR
                     MLTEGERVEHIDAALVKFGFPVGPIQLLDEVGIDTGTKIIPVLEAAYGERFSAPANVV
                     ASILNDDRKGRKNGRGFYLYGEKGRKSKKQVDPAIYKLIGVQGQSRLSAQQVAERCVM
                     LMLNEAARCFDEKVIRSARDGDIGAVFGIGFPPFLGGPFRYMDALGPGEMVATLQRLA
                     ALYGPRYAPCEQLVRMAERREHFWTNGETDQGN"
     gene            complement(13238..14548)
                     /gene="fadI"
                     /locus_tag="OPV72_002215"
     CDS             complement(13238..14548)
                     /gene="fadI"
                     /locus_tag="OPV72_002215"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461331.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase FadI"
                     /protein_id="HCR9914499.1"
                     /translation="MRQALPLVTRQGDRIAIVSGLRTPFARQATAFHGIPAVDLGKMV
                     VGELLARSEIPADAIEQLVFGQVVQMPEAPNIAREIVLGTGMNVHTDAYSVSRACATS
                     FQAVANVAESLMAGTIRAGIAGGADSSSVLPIGVSKALARVLVDVNKARTTRQRLTLF
                     SRLRLRDLLPVPPAVAEYSTGLRMGDTAEQMAKTYGITREQQDALAHRSHQRAAQAWA
                     EGKLAEEVMTTYVPPYKNPFAEDNNIRGASTLADYAKLRPAFDRKHGSVTAANSTPLT
                     DGAAAVILMTESRAKELGLRPLGYLRSYAFTAIDVWQDMLLGPAWSTPLALERAGLTM
                     ADLTLFDMHEAFAAQTLANLQLLGSERFAREVFGRAQATGEVDDAKFNVLGGSIAYGH
                     PFAATGARMITQTLHELRRRGGGFGLVTACAAGGLGAAMVLEAE"
     gene            complement(14726..15010)
                     /locus_tag="OPV72_002216"
     CDS             complement(14726..15010)
                     /locus_tag="OPV72_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcZ/YiiS family protein"
                     /protein_id="HCR9914500.1"
                     /translation="MSKCSADETPVCCCMDVGTIMDNSDCTASYSRVFATRAEAEETL
                     AALTEKARSVESEPCQITPTFTEESEGVRLDIDFVFACEAETLIFQLGLR"
     gene            15381..16688
                     /gene="fadL"
                     /locus_tag="OPV72_002217"
     CDS             15381..16688
                     /gene="fadL"
                     /locus_tag="OPV72_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416846.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="long-chain fatty acid transporter FadL"
                     /protein_id="HCR9914501.1"
                     /translation="MSQKTLFTKSALAVAVAIISTQAWSAGFQLNEFSSSGLGRAYSG
                     EGAIADDAGNVSRNPALITMFDRPTFSAGAVYIDPDVNISGTSPSRRTLDADNIAPTA
                     WVPNVHFVAPINDQFGWGASITSNYGLATEFNDTYAGGSVGGTTDLETMNLNLSGAYR
                     LNEAWSFGLGFDAVYARAKIERFAGDLGQLVAAQNPALAPVAGQILSDTKIAHLNGNQ
                     WGFGWNAGILYELDKNNRYALTYRSEVKIDFKGNYSSDLPIAINRFNLPIPTATGGAT
                     QSGYLTLNLPEMWEVSGYNRVAPQWAIHYSLAYTSWSQFQELKAKSTAGDTLFEKHEG
                     FKDAYRIALGTTYYYDDNWTFRTGIAFDDSPVPAQNRSISIPDQDRFWLSAGTTYAFN
                     KDASVDVGVSYMHGQSVKINEGPYQFESEGKAWLFGTNFNYAF"
     gene            complement(16749..17504)
                     /gene="mlaA"
                     /locus_tag="OPV72_002218"
     CDS             complement(16749..17504)
                     /gene="mlaA"
                     /locus_tag="OPV72_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipid-binding lipoprotein MlaA"
                     /protein_id="HCR9914502.1"
                     /translation="MKLRLSALALGTTLLVGCASSGTEQQGRSDPFEGFNRTMYNFNF
                     NVLDPYVVRPVAVAWRDYVPQPARNGLSNFTGNLEEPAIMVNYFLQGDPYQGMVHFTR
                     FFLNTLLGMGGFIDVAGMANPKLQRVEPHRFGSTLGHYGVGYGPYMQLPFYGSFTLRE
                     DGGDMADTLYPVLSWLTWPMSIGKWTIEGIETRAQLLDSDGLLRQSSDPYIMVREAYF
                     QRHDFIANGGKLKPQENPNAQAIQDELKEIDSE"
     gene            17793..18734
                     /locus_tag="OPV72_002219"
     CDS             17793..18734
                     /locus_tag="OPV72_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HCR9914503.1"
                     /translation="MDSLNDDKINRHSSDLEVESEEKQSGKEIEVDEDRLPSRAMAIH
                     EHIRQDGEKEMERDAMALLWSAIAAGLSMGASLLAKGIFHVQLEGVPGGFLLENLGYT
                     FGFIIVIMARQQLFTENTVTAVLPVMQNPTLSNVGLLMRLWGVVLLGNLIGTGVAAWA
                     FEYMPIFDEETRDAFVKIGMEVMKNSPTEMFANAIISGWIIATMVWMFPAAGGAKIVV
                     IILMTWLIALGDTTHIVVGSVEILYLVFNGTLPWSDFFWPFALPTLAGNICGGTFIFA
                     LMSHAQIRNDMSNKRKEEARLRGERLERERKKAEKQR"
     gene            18810..18884
                     /locus_tag="OPV72_002220"
     tRNA            18810..18884
                     /locus_tag="OPV72_002220"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18843..18845,aa:Arg,seq:cct)
     gene            complement(19032..19656)
                     /locus_tag="OPV72_002221"
                     /pseudo
     CDS             complement(19032..19656)
                     /locus_tag="OPV72_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014609409.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         4787 a         5514 c         5089 g         4563 t
ORIGIN      
        1 ttctcattct caaggccggt gtgcggaatt tacccgaaag gcaattcagg cgggcggtat
       61 cacgctgggg catacatatc atgcgaaaga ttatggccca atgttaagaa gcgccggatt
      121 caccgctatt ggtacctatg aaatgccgcg cgagggtgac gtcatcatta ttcaacctta
      181 cgctggcgga aacccgagcg gtcacatggc gatatacgat ggcgcagagt ggtattcaga
      241 ttttaaacaa cgcgatatgt gggccggccc gggctaccgg gcagccaggc cctcatatac
      301 catctacagg aagaattaat gaaaacgttc tcccttgtcg cgcttatcct gttgctttgt
      361 agttgctctg cgcctcatca cgacagtacg caggccgtga agcagttcta tacctcatgg
      421 atgacgacgt tcatgaacga tgtgaatacc cctgacgaca ccaccgcctt aatgcaacgt
      481 tacgttgcta aagaggttat tcatcgcctg gcgctaatac agtcccttta tgaacaggag
      541 attgtagggg cagattattt tatgtatgcg caggactatg cgccagagtg gattccacag
      601 ttacgggttg ggaaggcaca ccctttcctc ggcggagaaa aagtggatgt tctgttggct
      661 acagagtcaa cgcccatcca cctggaagtt tatacccgtt gggaagaggg acgctggaaa
      721 atttaccgcg ttcgggatgc tgataaggat tatgaacagc cgatttatga cgcaggcgcc
      781 atcacccagg ctgaggcctg gtcagcaaaa gtcgcgccgg aatatgagaa gcattaaaaa
      841 agggaaccgc catcgttctc ttgttcgtac cggagaggtt aaagagccta tttcatcagg
      901 ctcttattcc gtcgctgaaa acagcaagcc gaaaataacc caggcattat ttaaaatatg
      961 aagtgttatc ggtatcatta gtccacggct tctcattcga acaacgcata atatcgatga
     1021 aaaaacaaac agataaacaa aagtcaccgc aaagagatat tgtgtatgca taaatgcaaa
     1081 agcgagtgaa gtaataataa taccggaaac tcttgagtat cgaccccaac cgatactgct
     1141 gtttaataaa aaccctctga atataatttc ctccgccaca ggagccagaa agcacatcac
     1201 cagcgtgtta agaaatttat gaagaaaaaa ttgccttgat aactcggcca tccagggttc
     1261 cgggccacta aaaacattgt agagaacggt aaggcacacc agggccagcg ccggaacaaa
     1321 acattccaca aatgataagc ggcccaatga taaaaacgga taatactttg aataaatact
     1381 ccaggcggca atcgcgtaga caaaaacaat actatatata aaaggcgcag ccagacctcc
     1441 caaataaagc caggcatagg aaggcgaaaa tgaggcaaaa acaaaaatgc cgaacaaacc
     1501 aaataaaaca gccacacaac tcaaactatg cctaatttta tctaatgtat tagttggcat
     1561 ttatataata tccatataat ttgttgttcc ctgaatgaaa aaacaggtcg cattagcgac
     1621 ctgtttcatt gttgatacta caacgtaata gtcaggctta caacttacgc atcaccagcg
     1681 tggcgttggt gccgccaaaa ccgaagctgt tagacattac ggtagtcagt tcacgctcgg
     1741 tcgtttcggt cacgatgttc aggcccgcag cctgctcatc cagctcttcg atgttgatac
     1801 tcggcgcgat aaaaccgtgc tccagcatta gcagagagta gatggcttcc tgcacgccag
     1861 ccgcgcccag cgagtggccg gtcatcgctt tggttgcaga aattgccggg ctgttatcgc
     1921 caaacacttc acggattgca ccgagttctt tcacgtcgcc taccggcgtg gacgtaccgt
     1981 gagagttcag gtagtcgatc ggcgtgtcta cgccgtgcat cgccatctgc atgcaacgta
     2041 ctgcgccttc gccagacgga gcaaccatgt ctgcgccatc ggatgttgcg ccatagccga
     2101 cgatttccgc atagatatgc gcgccgcgcg ccagagcgtg ctccagctct tcgacaacaa
     2161 ccataccgcc accgcccgcg atgacaaacc catcacggtg cgcatcatag gtacgggacg
     2221 ctttttcagg cgtatcgtta tatttggtgg acagtgcccc catcgcatcg aactcacagg
     2281 ccatttccca gcacagctct tcgccgccgc cagcaaaaac gatgtcctgt ttgcccagtt
     2341 ggatctgttc aaccgcattg ccgatacagt gtgcggaggt cgcgcaagcg gagctaatgg
     2401 agtagttcac gccataaatt ttaaacggcg tagcgaggca ggcggaaacg ccggatgcca
     2461 ttgctttcgt caccacatac gggcccacag ctttcagacc acgcgggcta cgcatggcgt
     2521 ctgcgccaaa gacctggaat ttcggggagc cgccgccgga acctgcaatc aggccgacac
     2581 gcgggttatt ctgatagact tccggcgcca gaccggcgtc ggccactgcc tgctccatag
     2641 acagataagc atagatggag gcgtcgctca taaagcgcac gactttgcgg tcaatgaggc
     2701 cagtggtatc cagttttacg ttgccccata cctggctacg catgccggcg tccttcagct
     2761 cctgagagaa agtgatccct gaacgtcctt cacgcagaga tgccaggact tcctgctggt
     2821 tattaccgat gctggaaacg atgcccaggc cagtaatcac tgcacgtttc attcaatacc
     2881 tctgtaattc gcactatttt taagtttcga ttggcacaat agcgtacact tgtacgccga
     2941 acaagtccga tcagccattt agtacggaaa tttgcgccat caggcacaca tcgttaagat
     3001 cgcgataccg cccgtcagac gagtaactta cgtgaaacaa tacgccatac aacccgccac
     3061 actcgaattt aacgctgagg gtacacctgt ttcccgagat tttgatgatg tctatttttc
     3121 taatgacaat ggactcgaag agacacgcta cgtttttctt ggcggcaatc gtcttgcgga
     3181 gcgatttccc gtacattcac atccattatt tatagtcgcg gaaagcggtt ttggcaccgg
     3241 actcaacttc ctgacgctgt ggcaggcgtt tgacagcttt cgttctgcgc acccacaggc
     3301 gacgctgcaa aggttacatt tcatcagctt tgagaaattc ccgttaacgc gcgacgatct
     3361 ggcgctggcg caccaacact ggccggagct cgcgccctgg gcagagcagc tgcaggcgca
     3421 atggccgctg ccgctcccgg ggtgccaccg cctattgctg gatcggggtc gggtgacgct
     3481 ggatttgtgg tttggcgata ttaatgagct gaccgaccaa ctggacgcca cgctgaatca
     3541 aacagtcgac gcctggttcc tcgacggttt tgccccggcg aaaaatccgg atatgtggac
     3601 gccaaacctg tttaacgcga tggcgcggct ggcgcggccc ggcgcaacgc tggcgacgtt
     3661 tacctcggcg ggtttcgtcc gtcggggatt acaggaagcc ggttttacca tgcaaaaaca
     3721 caaaggcttc ggacgtaaac gcgagatgct ttgtggagtg atggaacaac acctcatgcc
     3781 gaccctttcc gcgccctggt tttactgcag cggaagcgaa aaacgtgaaa cggcgatcat
     3841 tggcggcggc atcgccagcg cgctgttatc actggcgtta ctgcgtcgcg gctggcaggt
     3901 gacgctctat tgcgcagatg atcagcccgc ccagggcgct tccggtaatc gacagggcgc
     3961 gctttatccg ctccttagca aacatgacgc cgccattaat cgctttttcc cgaccgcatt
     4021 cacctttgcc cgtcgcctgt atgatgccct gcccgtctct tttgatcatg cctggtgcgg
     4081 cgtgacacag ctcggatggg atgagaaaag ccagcagaaa attgcccaga tgctgtccct
     4141 ggcgctgccc gccggactgg cctcggcgct caatgccgaa gaggcggaac aggcggttgg
     4201 cgtgacgaca cgctgcggag gaattaccta tccggcaggc ggctggctgt gcccggaaca
     4261 attaactcgc gcagtcatcg cactggcgac tgaacagggt ttacaaacgc gctttcgcca
     4321 tacgctcacg tcgctcgttg cgcaggagtc gcgctggcaa ctgcgcttta cgtcaggtga
     4381 aaccgccagc catgagactg tcgtcctggc gaacggccat cagattaacc gttttgatca
     4441 gacccggccg ctgccggttt atgccgtcgg ggggcaggtc agtcatattc ccaccacccc
     4501 cgccctctcg gcgttgcgtc aggtgttatg ctacgacggc tatctgacgc cgcaaaatcc
     4561 gcataatcag cagcactgta ttggcgccag ctatcaccgg ggcgacgaaa gcaccgtctg
     4621 gcgcgaagaa gatcagcgtc agaaccgaca gcgtctgctt gactgttttc cggatgcgaa
     4681 ctgggccaca gaggttgacg ttagcggcaa cagcgcccgt tgcggcgtgc gttgcgccac
     4741 ccgcgaccat ctgccgatgg tgggcaatgt cccggattac cacgccacgc tgacgcatta
     4801 cgccgattta gccgataata aaacgtcggc ggcgtctgcg cctgtgtatc cgggtttatt
     4861 tatgctcggc gcgctgggat cgcgtggttt gtgttcagcg ccattatgcg cagaaattct
     4921 ggcggcgcag atgagtaacg agccgattcc actggatgcc ggtacgctgg cggcgttaaa
     4981 tccaaatcgg ttatgggtga gaaagttatt gaagggaaaa gcggtgaagt aatgggccag
     5041 tcaatagcgg aaggcggcaa gcgtcgcctt ccggtccacg gcgttattgt tttgccttgt
     5101 cgaacaaatt gtcccacatc gctttgacta acgcctgatc gcgcggcgac agttcgccgg
     5161 cgccgatcgc tttctccaga ctttggctaa cgttggcata gaccgcctca acggagtggt
     5221 catcaccgct ctccagctcg gcaatggcta acgtcaggtg gccacgcagg tatccactgg
     5281 caaaaagctc atcgtcgctg gcgtgctcta ccatatcgtc aattaatgcc agaatgcgtg
     5341 attcaaactc cgcgatcatc ttctttcctc attgtaaacg tggcgctggc tttaattaag
     5401 cgcttccggc cacgggaact gttccgcctt aagttcgggc gtgtgatagt aattctgtag
     5461 cgctttgatg aagcgggccg gacgttcagg aatgccctgc tccagatacg ccattacctg
     5521 cgcatgaacc cggcgctgaa acgccacgcg atccggctca atatcgcctt ccagattgtc
     5581 gcaactaacg tttaaaggga taccccgccg ccacgcaaaa caaccagtcg aaagcctgtg
     5641 gcttcacctc aacgtcttca aattgacttt gggtctgcgc gtcgcgtccg tccgggcagt
     5701 accagtaacc aaagtcgacc agttcgcggc gcgccttacc ggcgatacac cagtgagaaa
     5761 tctcatgcag cgcgctggcg taaaacccat gcgcaaagac gatacggtgg tacggtacct
     5821 gcgcgtcagc aggaagatag atcggttcgt cgtcgccttt aatcagacgg gtattaaatt
     5881 cttcggcaaa gcagccgtta aaaatctcaa ttaattgttc gtaatggtgc gtactgttca
     5941 ttaattcatc cccaaccagt ggaggatctc ctgtccgtgg ctatcataaa gtaacctggc
     6001 gctcatcacc gccgagacaa taacgatcat cggtctgata agcttttggc ctttgctcaa
     6061 caccagacgc gaccccattc gcgcccctaa aaactgacca accagcatca caaagcccgt
     6121 cgcccagatc actttgccgc cgatgataaa taacagcagg ccgccaacgt tggaggtagc
     6181 gttaagcact ttggcatgtg ccgtggattt cgccaggtta tagccacata aggtgacaaa
     6241 cgccagagcg taaaacgacc ctgcggcagg cccgaaaaag ccgtcgtaaa acccgacgca
     6301 tcccccggct atcagcgcga acggtaatcc atacaggcgg cgctggcgat cttcctcgcc
     6361 cagcttcggc atcaataaaa aatagaggcc gatgaaaatc accaggatgg gcaagatctg
     6421 gcgcaaaata tccgcctgca cgtgctgcac cagcagcgcg ccgctcatcg agccaatgaa
     6481 cgtcatcaga atattgagct tttgctcggc caggtttacc actttacggc gaataaaata
     6541 gagcgaagac gagagggagc cgccgcacgc ctgtaattta ttggtcgcca acgcgtttgc
     6601 cggcgacatc ccggcggcca tcagcgcagg gatagtgagc agccctccgc ctccggcgat
     6661 agaatcgata aatcctgcca gtacggcgac aaaaaacagc accaccagca gcagcgggga
     6721 gaccataaac agatcataaa aattgtccat cagagtacat gctcatccag tagcgcctgg
     6781 caggaaggcg gcaacggcgg cggtgtcttc ttctcaggct ttgtggtgcc aggttttggc
     6841 ggttcgaacc agctttgcag ttcagcgccg catccatcgc ccggcggggg taaaggttga
     6901 tcttcgcact ccaggctgtc ggcagggcag cgtaaacgca cgtgcatatg cgcgcgatgc
     6961 tggaaccagg ggcgtacttt acgtagccag tcacgatcgc ttccggcatc gaggcaaagc
     7021 tgttgtttaa tagccggatt gacgaaaata cgggtgacgt cattgtcttg tgccgccagt
     7081 ttgatcagac tggcgatatc cgacgaccag cgcgacggca cgacatgttt accgtcgcgg
     7141 gacaccagat ctaacgcctg cgggcgcaat agctgcgcct ggctccagcg cgttttcggc
     7201 aactgcaaga aaatatccac atcaagcccg gtctgatgac tggcgtgtcc gccattaaag
     7261 cggcctccgg caggcatccc catgtcgcct atcaggacgg ttccgagccc ccgttgctgc
     7321 gcctgatgac tcaaccgctg gataaacatg accagatccg ggtggccgaa ataacggcgc
     7381 tgatcggtgc gcatcacctg ataattatcg gactgtaccg gcaacgtgtc ggcgccaatg
     7441 atgcatccgt tggcaaagct accgatagac tgggcggcgc cggggacagg atgggttatt
     7501 ttctgccacg gcgtcgccgc caggctggcg ctactgacaa accatgccag cagcgcaatc
     7561 gcggtttttt tcatttctta ccagcgtgga atctctgtct ttacatccgc attctgtgcc
     7621 cgatggcgca gcaggtgatc catcagtacg atcgccagca tggcttctgc gatcggcact
     7681 gcgcgaatcc ccacacacgg atcgtggcgc cctttggtga tcatctcgac ctcttcaccc
     7741 atccggttga tcgtacgtcc cggcacggta atgctggagg taggtttcag cgccatatgc
     7801 gccacaatgt gttgcccact actgatgcca ccgaggatgc cgccagcgtg gttgctctga
     7861 aaaccctgcg ccgtgatttc atcgcgattc tggctgccgc gcagcgccac cacgttaaat
     7921 ccttcgccga tctccacgcc tttcaccgca ttgatgctca tcagcgcatg ggcgatgtcc
     7981 gcatccagtc ggtcaaatac cggttcgcca agccctgccg gcacgccgct cgccatcacc
     8041 gtcactttcg cgccgatgga gtcaccctct tttttcagcg cgcgcatcag ttcgtccagc
     8101 gcgtcaagtt tgtccgcatc ggggcaaaag aacggattaa gctcaacctg acgccagtct
     8161 ttaatctcca gcggaatgtc gcccatctgg gtcaggcagc cgcggatttc gatgccgaac
     8221 ttttccgcca agtatttctt ggcgatcgcc cctgccgcta cgcgcatcgc ggtttcacgc
     8281 gcggaagaac gtccaccgcc gcggtaatcg cgcaggccgt atttctgctc ataggtgtaa
     8341 tccgcgtgtc ccgggcgaaa aacatcttta atcgcgctgt agtcctgcga gcgctgatcg
     8401 gtgttttcaa tcagcaggcc aatactggtg ccggtcgtca cgccatcaaa cacgccggag
     8461 agaattttta cctggtccgg ttcgcggcgc tgagtagtat agcgcgaggt gccagggcgg
     8521 cgtctgtcga gatcgtgctg cagatcggcc tccgtcaacg ggatgccggg cggcacgcca
     8581 tcgacgatac ccccaagcgc cagcccgtgt gattcgccga aagtggttac gcgaaagagt
     8641 tgtccaattg tgtttcctgc catcacggct ccgttatcgt tgttgtcgtt tgcgtgtttt
     8701 aatctttata aatattgaaa tgttcacggg ccgcgagcaa ctgcgctttg gtcaacataa
     8761 agacgccatc gccgccgttg tcaaactcca gccaggtgaa cggcacatcc ggatactgct
     8821 ccatcagatg taccatgctg tttccgactt cacaaatcag aacgccatca tcggacagat
     8881 aatccggcgc atttcccagg atacggcggg tcaatttgag gccgtcagtg ccggacgcca
     8941 gccccagctc aggttcgtgg cgatattcgt tcggcagatc ggacatatcc tccgcatcga
     9001 cataaggcgg gttagtgaca atcagatcgt actgaacttt cggcagatcg cggaacagat
     9061 cggaacggat tggcgtcacg tgatggataa gaccgtgttc ttcaatgtta tgctcggcga
     9121 cagccagcgc atccggcgaa atatcgaccg catcaacctc tgcgtccggg aaagcataag
     9181 cacaggcgat ggcgatgcag ccgctgccgg tacacatatc cagaatatat ttcggctgtt
     9241 ggctaataag gccagcgaag tggttattaa tcagctcgcc aatcggtgaa cgcggcacca
     9301 gcacgcgctc atcaacataa aattcgtggc cgcagaacca ggctttattg gtcaggtagg
     9361 ctaccgggat acgctcgtta atgcgacgaa tcactcgctc gacaatgcgg tgtttttcgc
     9421 tggacgtcag ccgcgcggtc cgcatatcct ccggaatatc cagcggcaga taaagagacg
     9481 gcaacaccag ttgtaccgct tcatcccacg ggttatcggt accgtgtcca taccagatat
     9541 tcgccgcgct aaagcggctt accgcccagc gcaacatgtc ctgaatggta tgcagttcac
     9601 ttactgcttc atcgacgaaa attttatcca cgtattcctc cagggcatgc tcgcattaaa
     9661 ttcggcggct agtttgccac gaagacaggg ataaatcagc attgacgcgg cgggagaata
     9721 cgaaaaatcc gttttgaccg ttcggatatc ctccgggtcg ggtaaactaa ggcaaaagat
     9781 cagacgagac ccacgaatga aaaagaaaac atcgctcagc gaggaggacc aggcgctgtt
     9841 ccgtcagctg atggtcggca cccgaaagat taaacaggat actatcgtcc atcggccact
     9901 gcgcaagaaa atcacggaag tccctacccg aaggttaatt caggaacagg cggacgccag
     9961 ccactatttt tctgatgagt tccagccgct gctcaatacg gaagggccgg taaagtatgt
    10021 ccgtgaagat gtcagccatt tcgagctaaa aaaaatgcgc cgcggcgact attcgccaga
    10081 actgtttctg gatttacacg gcttaacgca gcttcaggcc aagcaggaac tgggggcgct
    10141 gattgccgcc tgccgtcggg aacatatttt ttgcgcctgc gtcatgcatg gacacggtaa
    10201 acatattctg aaacagcaaa cgccgttatg gctggcgcag catccgcatg tgatggcctt
    10261 tcatcaggcg ccgaaagagt acggcggcga cgccgcgctg ctggtgttga ttgaagtgga
    10321 agagtggcaa ccgcccgaat taccctgatg cggaattgcc ggatggcggc gcaagcgcct
    10381 tatcaggcag caaagattaa atcgctttcg ccattttcag attgcaggga ctcatttgcc
    10441 agttgaatgt ccccttgccg ctttcatcaa gcgtaacgtt ggcaattgcg gacgtcgtga
    10501 acatcggcgg cgtttcgccc ggacaaagct cagataccag gtatccgacc agaggtaagt
    10561 gagagatcac cagcaccgat ccgatctctt cattggccag cgcctgaagg taggcgctga
    10621 ccagaccgac atcgccacag ggcgttagct ccggcaggac atccacctga gtcggcagat
    10681 tcatacaatc gccgaccaca tctaacgtct gttcggcccg aagaaacgga ctcaccagaa
    10741 cacgttcgat atccactttt tgacctttca gccagttcgc catcaggcga gactcgtcac
    10801 acccacaaga ggtcaaggga cgaaccgaat cactggcggc atcgagggct gcgtcgccgt
    10861 gacgcatgat aaaaacttgc atattgcacc gcttttgtta accagtttca ccaacacgct
    10921 taccacatgc ccctattggc tgcggcaaaa atgcggtggc cggcattgtg ccttatccat
    10981 tcaccgaatg aaacgctgtt ttttacctca atggcgtaag tatagtcaat ccttgattat
    11041 tatttcgcca ctaaggaggc attcagtgcg gattcatatt ctctttgacc tcaatttccc
    11101 tggtcagttt ccccattcgt ccagaaatgc tccctgcgct ccgccatgcg cactaattgt
    11161 tcacaaggcg cgtaacgagg accgtaaagt gcggccaggc gctgtaatgt cgccaccatt
    11221 tcacccggcc cgagagcatc catatagcgg aacgggccac cgagaaacgg cggaaaaccg
    11281 ataccaaaca cggcgccgat atcgccatcg cgcgcgctgc gaatcacttt ttcgtcgaaa
    11341 cagcgcgccg cttcgttaag cattaacatg acacagcgct ctgccacctg ctgcgcagac
    11401 agtcgactct gcccttgcac gccaataagc ttataaatag cagggtcaac ctgttttttg
    11461 cttttacgcc ctttttcgcc ataaagatag aaaccgcgac cattttttct acctttgcga
    11521 tcgtcattca aaattgaagc gacaacattt gcaggcgcgc taaaacgttc tccatacgcc
    11581 gcctcaagca caggaataat tttagtgccc gtgtcgattc ctacctcatc caaaagttgg
    11641 attggcccca ccggaaaacc aaattttacc agggcggcgt caatatgttc gacgcgttcg
    11701 ccttcagtca gcatccgaat cgcctcattg atatatggcg caagaattcg gttaacataa
    11761 aacccggctt tatcactgac gactatcggg gttttaccct gttttttcgc cagcttaacg
    11821 gtcgtggcga tggtctgcgc ggaagtagac gcgtgaggaa tgacctcaac cagcggcatt
    11881 ttttcgaccg ggctaaaaaa gtgcaatcca atcacctgtt ccggtctggc cgcattcgcc
    11941 gcaatatcgc caatcggcag ggaagaagta ttggaggcaa aaatggtgtg agtagcgcaa
    12001 ttttgctcca cttccgccac catctgttgt tttaacggca gatcttcaaa caccgcttca
    12061 atgaccagat cacgatgact gaaaccacgg taatcggtcg aacctgatat caacgccaac
    12121 tgtttatcgc gttcgctggc tttgatatgg cggcggcgta cttttgtttc aagcagatcc
    12181 cagctgtatt tcagagcatg attgatcccc tgagtattta tatccttaat tcgtactggc
    12241 aaaccgcctt tacaggccgt aacccaggcg ataccgccgc ccattaaccc gccgcctaag
    12301 atgcccacgc tgttcagcgg gccgggcggt gcatcgctac cgggatcttt tttcacctcg
    12361 gtactggcaa aaaaaacagc gcgcagcgcc tgcgattgcg gcgtcatcgc cagctcgccg
    12421 aaagcgcgcg cttccgcgtc atagccgcta ctgctgccct gcgccagtcc ggtttcaatc
    12481 acatcaatga tccgctccgt cgccggataa ttaccctgcg ttttttgcgc cgtcttttta
    12541 cgcaccaggc gaaataacag cgcgcgcccc agcggccccg ccaggatacg ttcacggacc
    12601 ggtaaagtcc gctgcgccag gcgttctttt ttagccagct cgacagccgc ttccagtaaa
    12661 atagtttgcg gcaccacatc atcaaccagc ccggctttaa gcgcctgtct ggcgcgaagc
    12721 tgtttacctg tcaggatcat atccagcgcg gtactgaccc ccaccagccg cggaagacgc
    12781 tgcgttccgc ccgatcccgg taaaagccct aactgtacct ccggcagtcc gagaacggtt
    12841 ttaacgtcat cggtacagat acgccgatgg caggccagcg ccatttcaag accgcccccc
    12901 agacaggcgc cgtgaatggc ggcgataacc ggaacaggca acgcctggat ctccgccatc
    12961 agttgttgcc cctgacgcgc cagcgtttcc gcttcctgcg cgttttggca gtggcctatc
    13021 atgttgatat cagcgccagc aataaagtta tctgctttgg ctgagataaa aacaacgccc
    13081 tgcaacgctt tattttcccg gatctgcttc aggatggcgc gtacctgcgc ggcaaactcc
    13141 gctttcaggg tgttcacctt ttctccaggg acatcaatag cgacaaccgc gacattatcc
    13201 agacgcacgc taagcataaa agctgatgtg gtagtcatta ttccgcctcc agaaccatcg
    13261 ccgcgccaag accgccagcc gcgcaggccg tgaccaggcc aaaacctccg ccccgacgcc
    13321 gtaattcatg caacgtttgg gttatcatcc gcgcgcccgt tgcggcaaaa ggatgcccgt
    13381 aggcgattga gccgccgagc acgttgaatt tagcgtcatc cacctcccct gtcgcctgcg
    13441 cacgaccaaa cacctcacgg gcaaatcgtt cgctgcccag cagttgtaag ttcgccagag
    13501 tctgagcggc aaacgcttca tgcatgtcaa aaagcgtcag atcggccatc gtcaacccgg
    13561 cccgctccag cgccagcggc gttgaccagg ccggccccaa tagcatgtcc tgccagacat
    13621 caatagcggt aaaggcgtag ctgcgcagat aaccaagcgg gcgcagcccc agctctttag
    13681 cgcgggattc ggtcatcaga ataacggcgg cagcgccgtc ggtcagcggt gtactgttgg
    13741 cggcggttac ggagccatgt tttcggtcaa aagcgggacg cagtttagcg tagtccgcca
    13801 gcgtggaggc accgcgaatg ttgttgtctt ctgcaaaggg gtttttatac ggcggcacat
    13861 aggtcgtcat cacttcttcc gccagtttac cctccgccca tgcctgcgcg gcgcgctgat
    13921 gtgaacgatg cgccagcgcg tcctgctgtt cacgcgtaat accatacgtt ttcgccatct
    13981 gttcggcggt atcgcccatg cgcagaccgg tggaatactc agcaacggcg ggaggaacgg
    14041 gcagcaggtc gcgtaagcgc agacgagaaa aaagcgtcag ccgttggcgg gtcgtccggg
    14101 ctttattgac atcaaccagt acccgcgcca gggctttact cacgcctatt ggcagtaccg
    14161 acgacgaatc tgcgccgcca gcgatacccg cgcgtatcgt gccggccatc aggctttccg
    14221 ccacattcgc taccgcctga aaactggtgg cgcaggcgcg gcttacgcta taggcatcgg
    14281 tatgaacatt cattcccgta cccagcacaa tttcgcgcgc aatattgggg gcttccggca
    14341 tttgtactac ctgaccaaaa accagttgct caatggcatc ggctggaatt tcactgcgcg
    14401 ccagcagctc gcctaccacc atcttgccga gatcaacagc gggaatacca tgaaatgcag
    14461 tggcctgacg agcgaagggg gttcgtaacc cactgacaat agcaatgcga tcgccctgac
    14521 gggtgaccaa cggtaaagcc tgacgcatag tactcccctg taaaaaaata aattagtggt
    14581 ctgacctgat cacagtctta accaattttt tacatttagc caagcagaga gaaaagaaag
    14641 tgggagctaa ggcacagtga agggaaacga caaaaaaaga aaacgcctcc gccagatgat
    14701 gacggaggcg tcgtgaatga acggattaac gcaggccgag ctggaagatc agcgtttctg
    14761 cttcgcaggc gaaaacaaaa tcaatatcca gacgaacgcc ttcggattcc tcggtaaagg
    14821 ttggcgtaat ttggcaaggt tcagactcca cgctacgcgc tttttcggtt aacgccgcca
    14881 gcgtctcttc agcctctgcg cgggtagcga atacgcggct gtatgacgcg gtgcaatcgg
    14941 agttgtccat gatggttcca acgtccatac agcagcaaac cggggtttca tcagcactgc
    15001 atttactcat tgtagatttc ctctgtattt gcacccaggg tgccagataa acgatgggga
    15061 tattttacgc tcccggcatt cgcctctcca gtcgttaatg gtgggaaacg cgttaagtga
    15121 ccgaaatcac acttaaaaat gatctaaaac aaaaatcacg cgatcgggtg accgttaagc
    15181 ccgccgattt taccagccag atctcgtttc taagatcaca attgaaaaaa cttataaaca
    15241 tacttgcaac attctagctg gtcagaccta tactctcgcc actggtctga tttctaagtc
    15301 gtaccgcaga ccctacactt cgcgctcctg ttacagcatg taacatagtt tgtataaaaa
    15361 taatcaatga ggttatggtc atgagccaga aaaccctgtt tacaaagtct gctctcgcag
    15421 tcgcagtggc aatcatctcc acccaggcct ggtctgcggg ctttcagtta aacgaatttt
    15481 cttcctctgg ccttggccgg gcctattcgg gtgaaggcgc aatcgcagat gatgcgggta
    15541 acgttagccg caacccggcg ttaattacca tgtttgaccg cccgacgttt tcagcgggcg
    15601 cagtttatat tgatcctgat gttaatatta gcgggacatc gccatctcgt cggacgttag
    15661 atgcggataa catcgcgccg acggcctggg tgccgaacgt ccattttgtc gccccgatta
    15721 acgaccagtt tggctggggg gcttctatta cctctaacta tggtctggcg acagagttta
    15781 acgacacata cgccggcggc tcggttggcg gtacgaccga tcttgaaacc atgaacctga
    15841 atttaagcgg cgcttatcgc ttaaatgagg cctggagctt cggcctcggc tttgatgcgg
    15901 tatacgcgcg cgcgaaaatc gaacgttttg cgggcgattt aggccagttg gtcgcggcac
    15961 agaatccggc gctggcgccg gtcgcgggtc agattctcag cgacaccaag attgcccacc
    16021 tgaacggtaa tcagtggggc tttggctgga atgccggtat cctttatgaa ctggataaaa
    16081 ataaccgcta cgcgctgacc taccgctcgg aagtcaaaat tgactttaaa ggcaactaca
    16141 gtagcgatct tcccatcgct ataaaccgat ttaacctgcc tatcccaacg gcaaccggcg
    16201 gcgcgacgca gtcaggctac ctgacgctga atctgccgga aatgtgggaa gtgtccggtt
    16261 ataaccgtgt ggcgccacag tgggccatcc actatagcct ggcctatacc agctggagtc
    16321 agttccagga attgaaggca aaatcgaccg ccggcgatac gctctttgag aagcatgaag
    16381 gctttaaaga cgcttatcgc attgcgttgg gtaccaccta ttactacgat gacaactgga
    16441 cgttccgtac cggtatcgcc ttcgatgaca gcccggtacc agcgcaaaac cgttctatct
    16501 ctattccgga tcaggaccgt ttctggctga gcgccggtac gacttacgcc tttaacaaag
    16561 atgcgtctgt cgacgttggc gtctcttata tgcatggtca gagcgtgaaa attaatgaag
    16621 gcccttatca gtttgaatct gaagggaaag cctggctgtt cggtactaac tttaactacg
    16681 cgttctaatc tctttctgaa acggatcaaa aaggtgagca ttgcgctcac ctttttattt
    16741 actgccgttt attccgagtc gatctctttg agttcgtcct gaatcgcttg cgcgttcggg
    16801 ttttcctgcg gcttgagttt tccgccattg gcgataaagt catgacgctg gaagtatgcc
    16861 tcgcgcacca taatataagg atcggaagac tggcgcagca aaccatcgga gtccagcaac
    16921 tgcgcgcggg tttctatccc ttcgatagtc cattttccta tggacattgg ccaggtcaac
    16981 cacgagagca ccggatacaa ggtatccgcc atatccccgc catcttcacg cagcgtgaag
    17041 ctgccgtaga acggaagttg catataaggc ccatacccca cgccataatg gcccagtgta
    17101 ctgccaaagc gatgcggttc aacgcgctgc agcttaggat tcgccattcc cgcgacgtca
    17161 ataaagccgc ccatccctaa taaggtattc aggaagaaac gggtgaaatg caccataccc
    17221 tgataaggat cgccctgcag gaaatagttc accatgatcg ccggttcttc gaggttgccg
    17281 gtgaaattac ttaaaccgtt acgcgcaggc tgtggaacat aatcacgcca ggcgaccgcg
    17341 accggccgaa caacatacgg gtccagcaca ttaaagttga agttgtacat ggtgcggtta
    17401 aacccttcaa atgggtctga acgcccctgc tgttctgtac cggaactcgc acacccgacc
    17461 agcagtgtgg ttcccagcgc cagcgccgac aggcgaagct tcatagatgt ctccctgtga
    17521 attatggcta tcgctgattg ccatccatga cggaacgcta ccgtatccgc ctgtttaggt
    17581 gtgagcgatt ttaacagcac gtcaaacgat gtctatatgc gcgatctcat tgctctgagc
    17641 atagcctggt aacgcaacaa catgacggcc ctattctaac gaaacagata aaaacgagcg
    17701 tgattatttt tattttttcg gagaatgccc cggcctgggt aaatgaaaaa ccgctacgct
    17761 ttattaatat gtgttaatca gcaaggatca tcatggatag ccttaacgac gataaaatta
    17821 accggcacag cagtgacctg gaagttgaaa gcgaagaaaa acaaagcggt aaagagattg
    17881 aagtagatga agatcgtctt ccttcccgcg ccatggcgat tcatgaacat attcgccagg
    17941 atggtgaaaa agagatggaa cgcgatgcga tggctttgct ctggtcagcc attgccgcag
    18001 gactttctat gggggcatca ctcctggcga aagggatttt ccacgtgcag cttgaaggcg
    18061 ttcccggcgg ctttttactg gaaaatctcg gttatacctt tggttttatc attgtcatca
    18121 tggcccgcca gcaattattt actgaaaata ccgttaccgc cgtattgccg gtaatgcaaa
    18181 atcccacgct gagtaacgtt ggcctgctga tgcgcttatg gggcgtagtc ttattgggca
    18241 accttattgg caccggggtt gcggcgtggg cttttgaata tatgcctata tttgatgaag
    18301 agacccgcga tgcctttgtc aaaattggta tggaggtcat gaaaaatagc ccaacggaga
    18361 tgtttgccaa cgcgattatc tctggctgga tcatcgccac aatggtatgg atgtttcctg
    18421 ctgcaggcgg ggcaaaaatt gtggtcatta ttttgatgac ctggcttatc gcgctgggcg
    18481 ataccaccca tattgtcgtc ggttccgttg aaattttgta tttggttttc aacggcacgc
    18541 tgccctggag cgactttttc tggcccttcg cccttcccac acttgccgga aatatctgcg
    18601 gcggcacctt tattttcgca ttgatgagcc acgcgcagat ccgcaacgat atgagcaata
    18661 agcgtaagga agaagcgagg ctacgcggcg agcgcctgga acgggagcgg aaaaaagcgg
    18721 aaaaacagcg ctgagtggcg acggtttaac cagtcaggcg gcgctacact tactccggcg
    18781 aataaaaaac gctatactgg cgccgcgttg tccccttagt taaatggata taacgagccc
    18841 ctcctaaggg ctagttgcag gttcgattcc tgcaggggac accatgacct cttttaccca
    18901 cctctcacga atctcagcaa acccacacca cacaaggcgt tgcagcgttt ttgatgtctt
    18961 atgatctcca gcgaatagtg cctataaaca taacgaaaag catcccttta aagtcccctc
    19021 tcgctgttag aacttaacca aaagttagca ccttcacttt ccgacagata taggcccaga
    19081 acttcttttt tgccttctag attcagtgcc agaacggtat aaaccgcctt gctctgataa
    19141 cggccatcct cacggttttt ataatgaata gcgtccagcc agacgacggg ataaaccttc
    19201 tccagcgggc tctgttgcca ctgttttagt tcagggatga ctttatcggt actgcactga
    19261 cggtggcggt tgaaacgctg aaggcataaa gatcttcact ctcccggccg atgtcctgat
    19321 aactcatctc cagcgcaaac agtcgaatga tattgcgctc gatctcgtcg tacagggggt
    19381 ctgaagcttc ttcaccaatt atggctcaaa agtgccgtta cgattgcgcg gagttgccag
    19441 ttcaaaactg cctgttgggg ctttaatggc tttttgccgg aaccattttt acggtttgcc
    19501 tcaacatcct gagccagatg ggaatcaagt tcagcagaca gggtagagtc ggttaaatac
    19561 ttgattaatg gcgttaagat gccatctttg cccgttaatg cctggccgga cctgaagggc
    19621 tttaagtgct ttgtcgaaat cgaagggatg ggacatgtgc cattcttttt tattttatcg
    19681 ttcaatattt gctggctcac cagactacca tgaattaact cttcttttat tattatcgtt
    19741 ctttttggcg atattaactt attatttaat tgaaaaacca ctgagaaatt ccagaagtaa
    19801 atatatcaca gcaatattat tagcattatc tgtatttggg acgggtttaa ttggcgcatt
    19861 tatttttcat ataaatggag ttaaagacag ggaaatcaat aaatcagcaa gtgaatatgc
    19921 ttctgttact gacgtgtaca attattataa ata
//
LOCUS       DAJVBX010000073        19654 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.073, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000073 DAJVBX010000000
VERSION     DAJVBX010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 19654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19654
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.073"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(2..1048)
                     /gene="pyrC"
                     /locus_tag="OPV72_002222"
     CDS             complement(2..1048)
                     /gene="pyrC"
                     /locus_tag="OPV72_002222"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HCR9914504.1"
                     /translation="MTAPSQVLKIRRPDDWHVHLRDGDMLKTVVPYTSEIYGRAIVMP
                     NLASPITTVDAAIAYRQRILDAVPAGHDFTPLMTCYLTDSLDADELERGFHEGVFTAA
                     KLYPANATTNSSHGVTSVDAIMPVLERMEKLGMPLLVHGEVTHADVDIFDREARFIDT
                     VMEPLRQRLTALKVVFEHITTKDAAQYVRDGSYNLAATITPQHLMFNRNDMLVGGIRP
                     HLYCLPILKRNIHQQALRDLVASGFTRAFLGTDSAPHSRHRKETRCGCAGCFNAPSAL
                     GSYAAVFEEMNALAHFEAFCSLNGPQFYGLPVNTGWVELVRDEQQIPENIALADDSLV
                     PFLAGETVRWSVKK"
     gene            complement(1152..1751)
                     /locus_tag="OPV72_002223"
     CDS             complement(1152..1751)
                     /locus_tag="OPV72_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCR9914505.1"
                     /translation="MSRLGHRQHAKERHEKVFFAAALVVSGLLVGCNQLTQYTISEQE
                     INQALEKRNNFSKDIGLPGIADAHIVLTNLASQIGREEPNKVTLTGDARLDMNSLFGS
                     QKATMKLKLKALPVFDKEKGAIYLQEMEVVDATVTPEKMQSVLQTLLPYLNQSLRSYF
                     NQRPAYVLREDSSKGEALAKKLAKGIEVKPGEIVIPFTN"
     gene            complement(1836..2483)
                     /gene="grxB"
                     /locus_tag="OPV72_002224"
     CDS             complement(1836..2483)
                     /gene="grxB"
                     /locus_tag="OPV72_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin 2"
                     /protein_id="HCR9914506.1"
                     /translation="MKLYIYDHCPFCVKARMIFGLKNIPVELNVLQNDDEATPTRMIG
                     QKMVPILQKDDSRYLPESMDIVHYVDNLDGKPLLTGKRNPAIEEWLRKVNGYVNQLLL
                     PRFAKSAFDEFSTPAARQYFIRKKEASSGSFDNHLAHSAGLIKKIGDDLRLLDKLIVQ
                     PNAVNGELSEDDIHLFPLLRNLTLVAGIHWPTKVADYRDNMAKQTQINLLSSMAI"
     gene            complement(2547..3755)
                     /gene="mdtH"
                     /locus_tag="OPV72_002225"
     CDS             complement(2547..3755)
                     /gene="mdtH"
                     /locus_tag="OPV72_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdtH"
                     /protein_id="HCR9914507.1"
                     /translation="MSRVSQARNLGKYFLLIDNMLVVLGFFVVFPLISIRFVDQMGWA
                     AVMVGIALGLRQFIQQGLGIFGGAIADRFGAKPMIVTGMLMRAAGFATMGIAHEPWLL
                     WFSCFLSGLGGTLFDPPRSALVVKLIRPEQRGRFFSLLMMQDSAGAVIGALLGSWLLQ
                     YDFRLVCATGAILFILCALFNAWLLPAWKLSTARTPVREGMRRVMSNKRFVTYVLTLA
                     GYYMLAVQVMLMLPIMVNDIAGSPAAVKWMYAIEACLSLTLLYPIARWSEKRFRLEHR
                     LMAGLLVMSLSMLPIGMVGNLQQLFTLICAFYIGSVIAEPARETLSASPADARARGSY
                     MGFSRLGLAIGGAISYIGGGWLFDMGKALAQPELPWMMLGIIGFITFLALGWQFSHKR
                     TPRRMLEPGA"
     gene            3992..4576
                     /gene="rimJ"
                     /locus_tag="OPV72_002226"
     CDS             3992..4576
                     /gene="rimJ"
                     /locus_tag="OPV72_002226"
                     /EC_number="2.3.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S5-alanine
                     N-acetyltransferase"
                     /protein_id="HCR9914508.1"
                     /translation="MFGYRSNVPKVRLTTDRLVVRLVHERDAWRLADYYAENRHFLKP
                     WEPVRDESHCYPSGWQARLGMIGEFHKQGSAFYFALLDPEEKEIIGVANFSNVVRGSF
                     HACYLGYSIAQEWQGQGLMFEALTAAIRYMQRTQHIHRIMANYMPHNKRSGALLARLG
                     FEKEGYAKDYLLIDGQWRDHVLTALTTPLWTPGR"
     gene            4612..5259
                     /locus_tag="OPV72_002227"
     CDS             4612..5259
                     /locus_tag="OPV72_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceH family protein"
                     /protein_id="HCR9914509.1"
                     /translation="MKYELTATEARVIGCLLEKQVTTPEQYPLSVNGVVTACNQKTNR
                     EPVMNLTEQEVQEQLDNLVKRHFLRTVSGFGNRVTKYEQRFCNSEFGDLKLSAAEVAL
                     VTTLLLRGAQTPGELRSRASRMHEFSDMAEVESTLERLASREDGPYVVRLAREPGKRE
                     SRYMHLFCGDVDELSLQTSAPESASGDLQSRVEALESEVAELKQRLDSLLAHLGE"
     gene            5261..6184
                     /locus_tag="OPV72_002228"
     CDS             5261..6184
                     /locus_tag="OPV72_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCR9914510.1"
                     /translation="MRTLRIGIVVLGGIAQKAWLPVLTNTAGWTLQGAWSPSRDKALR
                     ICESWRIPYVDSLANLASGCDAVFVHSSTASHYAVVSELLNAGVHVCVDKPLAENLRD
                     AERLVALAAQKKLTLMVGFNRRFAPLYRELKTRLGTAASLRMDKHRTDSIGPHDLRFT
                     LLDDYLHVVDTVLWLAGGEARLASGTLLTSESGEMCYAEHHFSADKLQITTSMHRRAG
                     SQRESVQAVTDGGLYDVTDMREWREERGQGILIKPIPGWQTTLEQRGFVGCARHFIDC
                     VQNQTVPETAGEQAILAQRVVEALWRDAISE"
     gene            6488..8023
                     /gene="murJ"
                     /locus_tag="OPV72_002229"
     CDS             6488..8023
                     /gene="murJ"
                     /locus_tag="OPV72_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HCR9914511.1"
                     /translation="MNLLKSLAAVSSMTMFSRVLGFARDAIVARIFGAGMATDAFFVA
                     FKLPNLLRRIFAEGAFSQAFVPILAEYKSKQGEEATRIFVAYVSGLLTLALAVVTVAG
                     MLAAPWVIMVTAPGFADTADKFALTTQLLRITFPYILLISLASLVGAILNTWNRFSIP
                     AFAPTFLNISMIGFALFAAPYFNPPVLALAWAVTVGGVLQLVYQLPYLKKIGMLVLPR
                     INFHDTGAMRVVKQMGPAILGVSVSQISLIINTIFASFLASGSVSWLYYADRLMEFPS
                     GVLGVALGTILLPSLSKSFASGNHDEYCRLMDWGLRLCFLLALPSAVALGILAKPLTV
                     SLFQYGKFTAFDAAMTQRALIAYSVGLIGLIVVKVLAPGFYSRQDIKTPVKIAIVTLI
                     MTQLMNLAFIGPLKHAGLSLSIGLAACLNASLLYWQLRKQNIFTPQPGWMWFLMRLII
                     SVLVMAAVLFGVLHIMPEWSQGSMLWRLLRLMAVVIAGIAAYFAALAVLGFKVKEFVR
                     RTA"
     gene            complement(8105..8527)
                     /gene="flgN"
                     /locus_tag="OPV72_002230"
     CDS             complement(8105..8527)
                     /gene="flgN"
                     /locus_tag="OPV72_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis chaperone FlgN"
                     /protein_id="HCR9914512.1"
                     /translation="MTRLSEILDQMTTVLNDLKTVMDAEQQQLSVGQINGSQLQRITE
                     EKSSLLATLDYLEQQRRLEQNAQRSANDDIAERWQAITEKTQHLRDLNQHNGWLLEGQ
                     IERNQQALEVLKPHQEPTLYGADGQTSVSHRGGKKISI"
     gene            complement(8532..8825)
                     /gene="flgM"
                     /locus_tag="OPV72_002231"
     CDS             complement(8532..8825)
                     /gene="flgM"
                     /locus_tag="OPV72_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma-28 factor FlgM"
                     /protein_id="HCR9914513.1"
                     /translation="MSIDRTSPLKPVSTVQTRETSDTPVQKTRQEKTSAATSASVTLS
                     DAQAKLMQPGVSDINMERVEALKTAIRNGELKMDTGKIADSLIREAQSYLQNK"
     gene            complement(8917..9576)
                     /gene="flgA"
                     /locus_tag="OPV72_002232"
     CDS             complement(8917..9576)
                     /gene="flgA"
                     /locus_tag="OPV72_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body P-ring formation protein
                     FlgA"
                     /protein_id="HCR9914514.1"
                     /translation="MQTLKRGFAVAALLFSPLTMAQDINAQLTTWFSQRLAGFSDEVV
                     VTLRSPPNLLPSCEQPAFSMTGSAKLWGNVNVVARCANEKRYLQVNVQATGNYVAVAA
                     PVARGGKLTPANVTLKRGRLDQLPPRTVLDIRQIQDAVSLRDLAPGQPVQLTMIRQAW
                     RVKAGQRVQVIANGEGFSVNAEGQAMNNAAVAQNARVRMTSGQIVSGTVDSDGNILIN
                     L"
     gene            9733..10149
                     /gene="flgB"
                     /locus_tag="OPV72_002233"
     CDS             9733..10149
                     /gene="flgB"
                     /locus_tag="OPV72_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgB"
                     /protein_id="HCR9914515.1"
                     /translation="MLDRLDAALRFQQEALNLRAQRQEILAANIANADTPGYQARDID
                     FASELKKVMVRGREETGGVALSLTSSRHIPAQAVSSPAVDLLYRVPDQPSLDGNTVDM
                     DRERTQFADNSLKYQMGLTVLGSQLKGMMNVLQGGN"
     gene            10153..10557
                     /gene="flgC"
                     /locus_tag="OPV72_002234"
     CDS             10153..10557
                     /gene="flgC"
                     /locus_tag="OPV72_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001740734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgC"
                     /protein_id="HCR9914516.1"
                     /translation="MALLNIFDIAGSALAAQSKRLNVAASNLANADSVTGPDGQPYRA
                     KQVVFQVDAAPGQATGGVKVASVIESQAPEKLVYEPGNPLADANGYVKMPNVDVVGEM
                     VNTMSASRSYQANIEVLNTVKSMMLKTLTLGQ"
     gene            10569..11267
                     /gene="flgD"
                     /locus_tag="OPV72_002235"
     CDS             10569..11267
                     /gene="flgD"
                     /locus_tag="OPV72_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook assembly protein FlgD"
                     /protein_id="HCR9914517.1"
                     /translation="MSIAVNMNDPTNTGVKTTTGSGSMTGSNAADLQSSFLTLLVAQL
                     KNQDPTNPLQNNELTTQLAQISTVSGIEKLNTTLGAISGQIDNSQSLQATTLIGHGVM
                     VPGTTILAGKGAEEGAVTSTTPFGVELQQPADKVTATITDKDGRVVRTLEIGELRAGV
                     HTFTWDGKQTDGTTVPNGSYNIAITASNGGTQLVAQPLQFALVQGVTKGSNGNLLDLG
                     TYGTTTLDEVRQII"
     gene            11294..12505
                     /gene="flgE"
                     /locus_tag="OPV72_002236"
     CDS             11294..12505
                     /gene="flgE"
                     /locus_tag="OPV72_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook protein FlgE"
                     /protein_id="HCR9914518.1"
                     /translation="MSFSQAVSGLNAAATNLDVIGNNIANSATYGFKSGTASFADMFA
                     GSKVGLGVKVAGITQDFTDGTTTNTGRGLDVAISQNGFFRLVDSNGSVFYSRNGQFKL
                     DENRNLVNMQGMQLTGYPATGTPPTIQQGANPAPITIPNTLMAAKSTTTASMQINLNS
                     TDPVPSKTPFSVSDADSYNKKGTVTVYDSQGNAHDMNVYFVKTKDNEWAVYTHDSSDP
                     AATAPTTASTTLKFNENGILESGGTVNITTGTINGATAATFSLSFLNSMQQNTGANNI
                     VATNQNGYKPGDLVSYQINNDGTVVGNYSNEQEQVLGQIVLANFANNEGLASQGDNVW
                     AATQASGVALLGTAGSGNFGKLTNGALEASNVDLSKELVNMIVAQRNYQSNAQTIKTQ
                     DQILNTLVNLR"
     gene            12526..13281
                     /locus_tag="OPV72_002237"
     CDS             12526..13281
                     /locus_tag="OPV72_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgF"
                     /protein_id="HCR9914519.1"
                     /translation="MDHAIYTAMGAASQTLNQQAVTASNLANASTPGFRAQLNALRAV
                     PVDGLSLATRTLVTASTPGADMTQGQLDYTSRPLDVALQQDGWLVVQAADGAEGYTRN
                     GNIQVGPTGQLTIQGHPVIGEGGPITVPEGSEITIAADGTISALNPGDPPNTVAPVGR
                     LKLVKAEGNEVQRSDDGLFRLTAEAQAERGAVLAADPSIRIMSGVLEGSNVKPVEAMT
                     DMIANARRFEMQMKVITSVDENEGRANQLLSMS"
     gene            13295..14077
                     /gene="flgG"
                     /locus_tag="OPV72_002238"
     CDS             13295..14077
                     /gene="flgG"
                     /locus_tag="OPV72_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006819466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal-body rod protein FlgG"
                     /protein_id="HCR9914520.1"
                     /translation="MISSLWIAKTGLDAQQTNMDVIANNLANVSTNGFKRQRAVFEDL
                     LYQTIRQPGAQSSEQTTLPSGLQIGTGVRPVATERLHSQGNLSQTNNSKDVAIKGQGF
                     FQVMLPDGTSAYTRDGSFQVDQNGQLVTAGGFQVQPAITIPANALSITIGRDGVVSVT
                     QQGQAAPVQVGQLNLTTFMNDTGLESIGENLYIETQSSGAPNESTPGLNGAGLLYQGY
                     VETSNVNVAEELVNMIQVQRAYEINSKAVSTTDQMLQKLTQL"
     gene            14132..14830
                     /gene="flgH"
                     /locus_tag="OPV72_002239"
     CDS             14132..14830
                     /gene="flgH"
                     /locus_tag="OPV72_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body L-ring protein FlgH"
                     /protein_id="HCR9914521.1"
                     /translation="MQKYALHAYPVMALMVATLTGCAWIPAKPLVQGATTAQPIPGPV
                     PVANGSIFQSAQPINYGYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKT
                     SFGFDTVPRYLQGLFGNSRADMEASGGNSFNGKGGANASNTFSGTLTVTVDQVLANGN
                     LHVVGEKQIAINQGTEFIRFSGVVNPRTISGSNSVPSTQVADARIEYVGNGYINEAQN
                     MGWLQRFFLNLSPM"
     gene            14842..15939
                     /locus_tag="OPV72_002240"
     CDS             14842..15939
                     /locus_tag="OPV72_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body P-ring protein FlgI"
                     /protein_id="HCR9914522.1"
                     /translation="MFKALAGIVLALVATLAHAERIRDLTSVQGVRENSLIGYGLVVG
                     LDGTGDQTTQTPFTTQTLNNMLSQLGITVPTGTNMQLKNVAAVMVTASYPPFARQGQT
                     IDVVVSSMGNAKSLRGGTLLMTPLKGVDSQVYALAQGNILVGGAGASAGGSSVQVNQL
                     NGGRITNGAIIERELPTQFGAGNTINLQLNDEDFTMAQQITDAINRARGYGSATALDA
                     RTVQVRVPSGNSSQVRFLADIQNMEVNVTPQDAKVVINSRTGSVVMNREVTLDSCAVA
                     QGNLSVTVNRQLNVNQPNTPFGGGQTVVTPQTQIDLRQSGGSLQSVRSSANLNSVVRA
                     LNALGATPMDLMSILQSMQSAGCLRAKLEII"
     gene            15939..16889
                     /gene="flgJ"
                     /locus_tag="OPV72_002241"
     CDS             15939..16889
                     /gene="flgJ"
                     /locus_tag="OPV72_002241"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly peptidoglycan hydrolase FlgJ"
                     /protein_id="HCR9914523.1"
                     /translation="MIGDGKLLASAAWDAQSLNELKAKAGQDPAANIRPVARQVEGMF
                     VQMMLKSMREALPKDGLFSSDQTRLYTSMYDQQIAQQMTAGKGLGLADMMVKQMTGGQ
                     TMPADDAPQVPLKFSLETVNSYQNQALTQLVRKAIPKTPDSSDAPLSGDSKDFLARLS
                     LPARLASEQSGVPHHLILAQAALESGWGQRQILRENGEPSYNVFGVKATASWKGPVTE
                     ITTTEYENGEAKKVKAKFRVYSSYLEALSDYVALLTRNPRYAAVTTAATAEQGAVALQ
                     NAGYATDPNYARKLASMIQQLKAMSEKVSKTYSANLDNLF"
     gene            16954..18615
                     /gene="flgK"
                     /locus_tag="OPV72_002242"
     CDS             16954..18615
                     /gene="flgK"
                     /locus_tag="OPV72_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgK"
                     /protein_id="HCR9914524.1"
                     /translation="MSSLINHAMSGLNAAQAALNTVSNNINNYNVAGYTRQTTILAQA
                     NSTLGAGGWIGNGVYVSGVQREYDAFITNQLRGAQNQSSGLTTRYEQMSKIDNLLADK
                     SSSLSGSLQSFFTSLQTLVSNAEDPAARQALIGKAEGLVNQFKTTDQYLRDQDKQVNI
                     AIGSSVAQINNYAKQIANLNDQISRMTGVGAGASPNDLLDQRDQLVSELNKIVGVEVS
                     VQDGGTYNLTMANGYTLVQGSTARQLAAVPSSADPTRTTVAYVDEAAGNIEIPEKLLN
                     TGSLGGLLTFRSQDLDQTRNTLGQLALAFADAFNAQHTKGYDADGNKGKDFFSIGSPV
                     VYSNSNNADKTVSLTAKVVDSTKVQATDYKIVFDGTDWQVTRTADNTTFTATKDADGK
                     LEIDGLKVTVGTGAQKNDSFLLKPVSNAIVDMNVKVTNEAEIAMASESKLDPDVDTGD
                     SDNRNGQALLDLQNSNVVGGNKTFNDAYATLVSDVGNKTSTLKTSSTTQANVVKQLYK
                     QQQSVSGVNLDEEYGNLQRYQQYYLANAQVLQTANALFDALLNIR"
     gene            18630..19583
                     /gene="flgL"
                     /locus_tag="OPV72_002243"
     CDS             18630..19583
                     /gene="flgL"
                     /locus_tag="OPV72_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgL"
                     /protein_id="HCR9914525.1"
                     /translation="MRISTQMMYEQNMSGITNSQAEWMKLGEQMSTGKRVTNPSDDPI
                     AASQAVVLFQAQAQNSQYALARTFATQKVSLEESVLSQVTTAIQTAQEKIVYAGNGTL
                     SDDDRASLATDLQGIRDQLMNLANSTDGNGRYIFAGYKTEAAPFDQATGGYHGGEKSV
                     TQQVDSARTMVIGHTGAQIFNSITSNAVPEPDGSDSEKNLFVMLDTAIAALKTPVEGN
                     DVEKEKAAAAIDKTNRGLKNSLNNVLTVRAELGTQLSELSTLDSLGSDRALGQKLQMS
                     NLVDVDWNSVISSYVMQQAALQASYKTFTDMQGMSLFQLNR"
BASE COUNT         4664 a         5098 c         5568 g         4324 t
ORIGIN      
        1 tttatttttt tactgaccag cgtactgttt cacccgctaa aaaaggcacc agcgaatcat
       61 cagccagcgc gatattttcc ggtatctgtt gttcatcgcg aaccagttcc acccaccccg
      121 tattcaccgg caggccatag aattgcgggc cattcagtga acagaacgct tcaaagtgcg
      181 ccagcgcgtt catttcctca aacacggcgg cataactgcc aagagcggag ggggcgttga
      241 aacaaccggc gcagccgcaa cgggtctctt tacgatgacg tgaatgcggc gctgaatccg
      301 tccccaggaa ggcgcgcgta aaaccactgg cgaccaggtc gcgtaacgcc tgctggtgaa
      361 tattgcgttt cagaatcggc agacagtaca ggtgaggacg aatgccgcca accagcatat
      421 cattacggtt aaacattaaa tgttgaggcg taatggtcgc cgccaggttg tagctgccgt
      481 cacgtacata ctgcgcggca tctttggttg tgatgtgttc aaagaccact ttaagcgcgg
      541 tcagacgctg gcgtagcggt tccattacgg tgtcgataaa acgcgcttcg cgatcgaaga
      601 tatcaacatc cgcatgggtc acctcaccgt ggaccagcaa tggcattccg agtttttcca
      661 tccgctccag taccggcatg atagcgtcga ctgacgttac gccatgactg gagttagtgg
      721 tggcattggc cgggtaaagc ttggccgcag taaacacgcc ttcatggaaa ccacgctcca
      781 gttcatcggc atcgagcgaa tccgttaaat agcaggtcat taacggcgtg aaatcatgcc
      841 cggcgggcac cgcatcgaga atacgctggc ggtaggcgat cgctgcatca acggtcgtaa
      901 tgggggacgc caggttcggc atcacgatag cgcgaccata aatttcgctg gtatagggta
      961 cgaccgtttt taacatgtcg ccatcgcgaa ggtgaacgtg ccagtcgtcc gggcggcgga
     1021 tctttaaaac ctgggatggt gcagtcatta ataagctccg gctgaggaat agtctttttg
     1081 ccggaaacaa aggataagcg gaaacgtttt cgtttgcacg taaaaaaagg gcgcgagcgc
     1141 gccctccgaa atcaattggt gaaaggaata acgatttcac caggtttaac ttcaatgcct
     1201 ttcgcgagtt tcttcgctaa cgcttcgcct ttactactgt cctcacgcaa cacgtaagcg
     1261 ggccgctggt taaagtagct acgtaaagac tgatttaaat agggcaggag cgtttgtagc
     1321 actgattgca ttttctccgg cgtcacggtg gcgtctacta cttccatctc ctgaagatag
     1381 atggcgcctt tttctttatc aaagaccggc agggctttta gcttgagttt catcgtcgct
     1441 ttttgactgc caaacaggga attcatatcc agcctggcat cgccagtaag ggtgacttta
     1501 ttaggctctt cccgaccaat ctggctggca aggttagtca atacgatatg cgcgtcggca
     1561 atgccaggca gaccaatatc ttttgagaaa ttattccgtt tttcaagcgc ttgattgatt
     1621 tcttgttcgc taatggtgta ttgcgtaagt tgattacaac ccactaacag gccgctaact
     1681 accagcgcag cggcaaaaaa aactttttca tggcgttcct tagcatgttg cctgtgccct
     1741 aatcttgaca caaagcagca tgtcgcgcca gcggacatgg cgccactaaa aaaagctgaa
     1801 aaaggcggca agaaagggtt gccgcctggc gggcgttaga tagccattga ggagagtaaa
     1861 ttaatttgcg tctgcttagc catattatcg cgatagtccg cgacttttgt cggccagtga
     1921 ataccggcga ccagcgtcag attacgcaga agcggaaaca gatgaatatc atcttccgat
     1981 aattcgccgt taacggcgtt aggctgtacg atgagtttat ccagcaaacg taaatcatcg
     2041 ccgatctttt taatcagtcc ggcagagtgc gcaagatggt tgtcaaaact gccagatgag
     2101 gcctcttttt tgcggataaa atactggcgc gccgcagggg tagaaaattc atcgaaagcg
     2161 gattttgcaa atcgcggcag cagtagctga ttaacgtaac cgttaacttt gcgcaaccac
     2221 tcttcaatgg ctggattacg tttcccggtt aacagcggtt tgccgtcgag gttgtcgaca
     2281 taatgtacaa tatccatact ttcaggaagg tagcgactat catctttttg caggatgggc
     2341 accatctttt gaccaatcat ccgggtgggc gtcgcctcgt cgtcattttg taacacgtta
     2401 agttcaacgg ggatgttctt caggccgaaa atcatgcggg ctttaacgca gaaagggcaa
     2461 tgatcgtaaa tataaagctt cacgtttctc ctccatttga ctgtcggttc ctgaccagta
     2521 tggaggagat agcgacaggt atcaaatcag gcgccgggtt ccagcatccg gcgcggcgtg
     2581 cgcttatgac taaattgcca gcctaaagcc aaaaaggtga taaagccgat aataccgagc
     2641 atcatccacg gtagttcagg ctgcgcaagc gctttaccca tatcaaacaa ccagccgccg
     2701 ccgatataac taatcgcgcc gccaatggct aatcccagac ggctaaagcc catatagctt
     2761 ccccgcgccc tcgcgtccgc gggcgacgcg ctgagcgttt cgcgcgccgg ttcggcgata
     2821 accgagccga tgtagaaagc gcaaataagc gtaaaaagct gctgtaaatt gcccaccatc
     2881 ccgatgggga gcatgctcag cgacatgacg agcaaaccgg ccatcagccg atgctccagc
     2941 cgaaaacgct tttcgctcca gcgggcaatc gggtagagca acgtcagcga gagacacgcc
     3001 tcaatagcgt acatccattt cacggcagca ggcgaaccgg cgatatcgtt taccataatc
     3061 ggcagcatta acatgacctg taccgccagc atatagtagc ccgccagcgt cagcacgtag
     3121 gtgacaaacc ttttattgct catgacgcgg cgcattcctt cacgcaccgg cgttctggcc
     3181 gttgatagct tccaggccgg aagcagccat gcgttgaaaa gggcgcataa tatgaacaaa
     3241 atagcgcccg tcgcgcagac caggcgaaaa tcgtattgta gcaaccagct tcccagcagc
     3301 gcgccaatca ccgcgcccgc gctgtcctgc atcatcaaca gagagaagaa gcggccccgt
     3361 tgctccggac gaattaattt gaccaccagc gctgaacgcg gcgggtcgaa aagcgtaccg
     3421 ccgagaccgg aaagaaagca ggaaaaccac aagagccagg gctcatgcgc gatacccatg
     3481 gtggcaaagc ctgcggcgcg catcagcata ccggtgacaa tcatcggttt cgcgccaaag
     3541 cgatcggcga tggcgccgcc aaaaatgccc agaccttgtt gaataaactg acgcaggccg
     3601 agcgcgatcc ctaccattac ggcagcccac cccatttgat cgacaaagcg aatagagatg
     3661 agcgggaaga cgacgaaaaa acccagcacc actaacatgt tatcgatgag aagaaaatat
     3721 ttacccaggt tcctcgcctg cgagacgcgc gacatttccc ctcccgggaa ataaaagatg
     3781 agcgtcttct attctgcggc ggcgtttcgt tttttcctac cgttagcggg acaatatttt
     3841 tttatcaaaa gtccttttta atcgagagtt ttcatcaaaa tgtggcagca attcaaaaaa
     3901 tgacgatttg cgcttttcac agggcctggt tgcgcaggta tagtaatgtt actggcgtgc
     3961 tgaagacgtt acaggaagga gtaggtatag aatgtttggc tatcgcagta acgtgccaaa
     4021 agtgcgctta accaccgatc gtctggtggt acgtttagtg catgagcgtg atgcctggcg
     4081 tctggccgat tattacgcgg aaaatcgtca ttttttaaaa ccctgggaac cggtccgtga
     4141 tgaaagtcat tgttatcctt caggatggca ggcgcgtctg ggaatgatcg gtgaatttca
     4201 caaacagggc tccgccttct atttcgcgct acttgatccg gaagaaaaag aaattatcgg
     4261 cgtggcgaat ttttccaatg tggtgcgcgg ttcttttcat gcctgttatc tgggctattc
     4321 cattgcgcaa gagtggcagg ggcaagggct gatgtttgaa gccttaaccg ctgcgattcg
     4381 ctatatgcag cgcactcagc atatccaccg tatcatggcg aactatatgc cgcacaacaa
     4441 acgtagcggc gcgttgctgg cgcggcttgg ctttgaaaaa gaaggctatg cgaaagatta
     4501 cctgttgatt gatggacaat ggcgcgacca tgtcctgacg gcgttaacca cgccgttatg
     4561 gacgccgggg cgttgagcgg cttacggaat gagaggcaaa gggagaaaac gatgaaatat
     4621 gaattaaccg ccactgaagc gcgagtgatt ggctgtctgc tggaaaagca ggtgacaacg
     4681 ccggaacagt atccgctttc cgtcaacggg gtggtgacag cctgtaatca gaaaaccaac
     4741 cgtgaaccgg tgatgaacct gacggaacaa gaggtacaag aacagctcga taacctggtg
     4801 aaacgccact ttttgcgtac ggtcagcggg tttggcaacc gcgtcaccaa atatgaacag
     4861 cgcttctgta attccgaatt tggcgatctg aaacttagcg cggcggaagt ggcgctcgtc
     4921 actacgttgc tgctgcgcgg cgcgcaaacg cccggcgagt tgcgtagccg ggcgtcgcgg
     4981 atgcatgaat tcagcgatat ggcggaagtt gaatccacgc tggaacggct tgccagtcgt
     5041 gaggacggcc cgtatgtcgt ccgtctggcg cgtgaaccgg gtaagcgcga aagccgctat
     5101 atgcaccttt tttgcggcga cgtcgatgaa ctgtctctcc agacgtctgc gccggaaagt
     5161 gcgtcgggcg atcttcagtc gcgcgtcgaa gcgctggaaa gcgaagtggc ggagttaaag
     5221 cagcggctgg attctttgtt agctcacctg ggagagtaat gtgagaacat tacggattgg
     5281 cattgtcgtg ttaggtggta ttgcgcagaa ggcctggctg ccggtattaa ccaacaccgc
     5341 cggatggacg ttacagggcg cctggtctcc ttcgcgggat aaagccttac gtatttgcga
     5401 aagctggcgc ataccgtatg tggattcgct ggcgaattta gcgtccggct gcgatgcggt
     5461 cttcgtccac tccagtaccg caagccatta tgccgtggtc agcgaacttc tcaacgctgg
     5521 cgtccatgtc tgcgtggata aaccgctggc ggaaaatcta cgtgatgccg aacggctggt
     5581 ggcgctggcg gcgcaaaaaa aattgacgct gatggttggc tttaatcgcc gtttcgcgcc
     5641 gctgtaccgc gaactgaaga cgcgcctcgg cactgcggcg tcactgcgta tggataaaca
     5701 tcgtaccgat agcatcgggc cgcatgactt acgttttact ttgctcgatg actatctgca
     5761 tgtcgtggat accgttctgt ggctggcggg cggcgaggcg cgccttgcca gcggcacgtt
     5821 gctcaccagc gagtccggcg aaatgtgcta tgcggaacat catttttccg ccgacaaatt
     5881 acaaattacc accagtatgc accggcgcgc cggaagtcag cgtgaatcgg tccaggccgt
     5941 caccgatggc gggctgtatg acgtgacgga tatgcgtgaa tggcgcgaag agcgcgggca
     6001 gggtattctc atcaaaccca ttccgggttg gcaaacaacg cttgagcagc gtggttttgt
     6061 cggatgcgcg cggcatttca ttgactgcgt acaaaatcag acggttccgg aaacggcggg
     6121 ggagcaggcg attttggccc agcgcgtcgt ggaggcgctg tggcgggacg ccatcagcga
     6181 ataatcctct gtaacatctg gcggtagtaa ttcatcgtaa tccaggtact ataccctcaa
     6241 taattcgagt tgcagaaaag ctaacgcaca tgcagctcga agtatggcgg gtatatatgc
     6301 ccactctaca taatacctct tttcacagtg aataatggca aaccgtgggg agtctgtaag
     6361 gcctgataag acgttttgac gtcgccgtca ggcgcagtga tacagccgga tacggcagaa
     6421 gttgcgttat ccggtcgatg gatcagccat gcaggagttt tacgccaggg tctggaatac
     6481 aaaagaaatg aatttattga aatcgctggc tgccgtcagc tcgatgacta tgttttcacg
     6541 cgtgttgggc tttgcccgtg atgcgattgt cgccagaatt tttggcgcag ggatggcgac
     6601 cgacgccttt tttgtggcgt ttaaacttcc caatctacta cgccggatct ttgccgaagg
     6661 cgctttttct caggcctttg tgcctatcct ggcggaatat aagagcaagc agggtgaaga
     6721 agcgacgcgg atctttgtcg cttacgtttc cggcctgttg acgctggcat tggccgtcgt
     6781 gacggtggcc ggtatgctgg ccgccccgtg ggtgattatg gtaaccgcgc cgggttttgc
     6841 cgatactgcg gataaatttg cgctgacgac gcaactgctg cggattacgt ttccctatat
     6901 tctgctgatc tcgctggctt cactggttgg cgccattctc aacacctgga atcgcttctc
     6961 tattcccgct tttgcgccga catttcttaa tatcagtatg atcggttttg cattattcgc
     7021 cgcgccatac tttaatccgc cggtgctggc gttagcctgg gcagtcaccg tcggcggcgt
     7081 gctgcaactg gtgtatcaac ttccgtattt gaaaaagatc ggtatgctgg tgctgccgcg
     7141 cattaacttt cacgacaccg gggcgatgcg ggtggtcaaa cagatggggc cggcgatttt
     7201 gggcgtttcc gtcagtcaga tctcccttat catcaatacc attttcgcct cgtttctggc
     7261 ctccggctcg gtctcatggt tgtactatgc cgatcggttg atggagttcc cgtccggcgt
     7321 gctgggcgtg gcgttgggga ccatcctgtt gccgtcattg tcgaaaagct ttgccagcgg
     7381 caatcatgat gagtactgcc gcctgatgga ctgggggctg cgtttgtgct ttttactggc
     7441 gttgccgagc gcggtagcgc taggcattct ggcgaagccg ctgacggtct cgctgtttca
     7501 gtacggtaaa ttcaccgcct ttgatgcggc gatgacgcag cgggcgttaa tcgcctattc
     7561 ggtggggctg attggcttga tcgtcgtaaa agtgctggcc ccgggcttct attctcgcca
     7621 ggatattaaa acgccggtga aaatcgccat cgtgacgtta atcatgacgc agttaatgaa
     7681 cctggcgttt attggaccgc tgaaacacgc cgggctgtcg ctctctattg gtctggcggc
     7741 atgtctcaat gcgtcgctgc tgtactggca actgcgcaaa cagaatatct ttacgccaca
     7801 accggggtgg atgtggttcc tgatgcgtct gatcatttcc gtactggtaa tggccgccgt
     7861 gttgttcggc gtgttgcata ttatgccgga gtggtcgcaa gggtcgatgc tatggcgttt
     7921 gctgcgtttg atggcggtag tgatcgcggg tatcgcggcc tatttcgccg cgcttgccgt
     7981 gctgggcttt aaagtgaaag agtttgttcg ccggacggcg taaattcagt gcctgatagc
     8041 gctgtgctat caggcctaca aggcattcag gccggaaagg cgcaacgtcg ccatccggca
     8101 atgattagat agatattttt ttaccgccgc ggtgagagac ggaagtctga ccgtcagccc
     8161 cgtacaaggt cggctcctgg tgaggtttca gcacctccag cgcctgttga ttacgctcga
     8221 tttgcccttc cagcagccag ccgttgtgct ggttgaggtc gcgcagatgc tgcgtttttt
     8281 cggtaatcgc ctgccagcgc tctgcaatgt catcgtttgc gctacgctgc gcgttctgct
     8341 ccagacggcg ctgttgttcc agataatcca gcgtcgccag caacgagctt ttttcttctg
     8401 taatacgctg tagctggctg ccgttaatct ggcctacgga aagctgttgt tgctcggcgt
     8461 ccatcaccgt cttcaggtca ttcaggacgg tggtcatctg gtcaagtatt tctgacaaac
     8521 gagtcatacg cttatttatt ctgtaagtag ctctgcgcct cgcgaatgag cgagtctgct
     8581 atttttcccg tatccatttt taactcaccg ttacggatag ccgtttttaa tgcttcgacg
     8641 cgttccatat taatgtcgct gacgcctggc tgcataagct tcgcttgcgc gtcgcttaac
     8701 gttacgctgg cgctcgtcgc ggcggacgtt ttttcctgac gcgttttttg taccggcgtg
     8761 tcgctggttt cgcgcgtctg gacagtgcta acgggtttca aaggtgaggt acggtcaatg
     8821 ctcatttatt tatcctcatc gagggttacg ttgtagcggc cagctaccat catggttgaa
     8881 tatctcatcg gcagccgcga caaaatcttt acacaattat aggttaataa gaatattccc
     8941 atcagaatcg acggttccac tcacgatttg acccgatgtc atgcgcacgc gcgcattttg
     9001 cgcgacggcg gcattattca tcgcctgacc ttccgcattg acgctaaacc cctcgccatt
     9061 ggcgatgacc tgtactcgtt gacccgcttt gacacgccag gcctgacgta tcatcgtaag
     9121 ctgtaccggc tgcccgggag cgagatcgcg caaactgacg gcatcctgaa tctgacggat
     9181 atccagtacc gtccgcggcg gtaactgatc cagtctgcca cgttttagcg tgacgttggc
     9241 cggcgtcaat tttccgccgc gcgcgacggg cgcggctacg gcgacataat tgccggtcgc
     9301 ttgcacattc acctgcaaat aacgtttttc attggcgcag cgcgccacca cattgacgtt
     9361 gccccacagc ttcgcgctgc ccgtcatgct gaaggctggc tgctcgcagc tcggtagcag
     9421 attgggcggt gaacggagcg tgacaaccac ctcgtcgctg aagccagcca gacgctggga
     9481 aaaccacgtg gtcagctggg cgttgatgtc ctgcgccatt gtcagggggc tgaacagcaa
     9541 agccgccacg gcgaatcctc gttttaacgt ttgcatggta cttccccctg gttgatgtca
     9601 tgacaggatt ctacccgtgt gaagcaagca tcaacgcaat aaatagcgac gcattttgcg
     9661 tttattccgg cgataacgcg cgcgtgaagg catttaagct gtcggctgaa ttttgccatt
     9721 tgcggaggag atatgctcga caggctcgat gccgccttac gatttcagca ggaagcgcta
     9781 aatctgcgcg cgcaacgtca ggaaatatta gcggcgaata tcgccaatgc cgatacgccg
     9841 gggtatcagg cgcgcgatat tgattttgcc agtgagttaa aaaaagtgat ggtgcgcgga
     9901 cgggaagaaa ccggcggcgt cgcgttgtcg ttgacttctt ctcgccatat tcccgcccag
     9961 gcggtctctt ctcccgcagt ggatctgctt taccgcgtac ccgatcagcc ttctttggat
    10021 ggtaacaccg tagatatgga cagggaacgt acgcagtttg cggataacag tctcaaatat
    10081 cagatggggc ttaccgttct gggtagccaa ctcaaaggca tgatgaatgt gctacaggga
    10141 ggaaactaat tcgtggcgct gttaaacatt tttgatattg ccggatcggc gcttgccgca
    10201 cagtccaagc ggttgaacgt tgcggccagt aaccttgcga atgcggatag cgtcaccggc
    10261 ccggacggac agccttatcg cgccaaacag gtggtttttc aggtggacgc cgcgccgggt
    10321 caagccactg gcggggtaaa ggtcgccagc gtgattgaaa gtcaggcacc ggaaaagctg
    10381 gtttatgagc caggcaatcc gctggcggac gctaatggtt acgtcaaaat gcccaacgtc
    10441 gatgtggtcg gcgaaatggt caacacgatg tcagcctcgc gcagctatca ggcaaatatc
    10501 gaagtcctga ataccgtaaa aagcatgatg cttaaaacgc tgacattagg ccagtaaagg
    10561 aggcgcgtat gtctattgcc gtaaatatga atgacccgac caacacgggc gtcaaaacga
    10621 cgaccggcag cgggtcgatg accggaagca acgctgccga tctgcaaagc agtttcctga
    10681 ccttactggt cgcgcaattg aagaaccagg acccgactaa cccattacaa aataatgagt
    10741 taacgacaca gttggcgcaa atcagtaccg tgagcggcat tgaaaaactg aatacgacgc
    10801 tgggggctat ttccgggcaa atcgataata gtcagtccct acaggcgacc acgctgattg
    10861 gacatggcgt tatggtgcct ggcaccacaa ttctggcggg taaaggcgcg gaagaagggg
    10921 ccgtgacgtc cacgacgccg tttggcgtgg aattgcaaca gcctgcggac aaagtgacgg
    10981 caaccattac cgataaagat ggccgggtgg tacggacgct ggagatcggt gagttgcgag
    11041 ccggggtaca cacctttacc tgggatggta agcaaacgga cggaacaacg gtaccgaatg
    11101 gttcttacaa cattgcgatt accgccagca atggcgggac gcaactggtg gcgcagccgc
    11161 tgcaattcgc tctggtacag ggcgtgacga agggcagtaa cggcaacctg ttggatctgg
    11221 gtacctacgg caccaccaca ctcgacgaag ttcggcaaat aatctaagcc cttacactta
    11281 tcaggagtca gtcatgtctt tttctcaagc ggttagcggc ctgaacgctg cggccaccaa
    11341 ccttgatgtt atcggtaata acatcgccaa ctccgccacc tatggcttta agtccggtac
    11401 ggcatcattt gccgatatgt tcgccggttc caaagtgggg ttgggcgtaa aagtggcggg
    11461 gattacccag gattttaccg acggtacgac aacgaacacc gggcgcgggc tggatgtcgc
    11521 gattagccag aacggttttt tccgcctggt agacagcaac ggttccgtgt tctatagccg
    11581 caacggccag ttcaaactgg acgagaaccg taacctggtc aatatgcagg ggatgcagtt
    11641 gaccggctat ccggccaccg gtacgccgcc gaccattcag cagggggcga atcctgcgcc
    11701 gatcaccatt ccgaacacgc tgatggcggc gaaatcgacc accaccgcgt caatgcagat
    11761 caacctgaac tcaacggacc ctgtaccgtc taaaacgccc tttagcgtga gtgatgcgga
    11821 ttcgtataac aaaaaaggca ccgtcaccgt ttatgacagc cagggtaatg cccatgacat
    11881 gaacgtctat tttgtgaaaa ccaaagataa tgaatgggct gtgtacaccc atgacagcag
    11941 cgatcctgca gccactgcgc caacaacggc gtccactacg ctgaaattca atgaaaacgg
    12001 gattctggag tctggcggta cggtgaacat caccaccggt acgattaatg gcgcgacagc
    12061 ggccaccttc tccctcagct tccttaactc catgcagcag aacaccgggg ctaataacat
    12121 cgtcgccacc aatcaaaacg gctataagcc tggcgacctg gtgagctacc agattaacaa
    12181 tgatggcacc gtggttggca actactccaa cgagcaggag caggtgctgg ggcagattgt
    12241 gctggctaac ttcgccaaca acgaaggtct ggcatcccag ggcgataacg tctgggcggc
    12301 gacgcaggcc tccggggtag cgctgctggg gactgccggt tccggcaact tcggtaagct
    12361 gacgaacggc gcgctggaag cctctaacgt ggatttgagt aaagagctgg tgaatatgat
    12421 cgtcgcgcag cgtaactacc agtcgaatgc gcagaccatc aaaacccagg accagatcct
    12481 caatacgctg gttaacctgc gctaagcgcc tgacgggata gcttaatgga tcacgcaatt
    12541 tataccgcca tgggggcggc cagccagacg cttaaccagc aggcggtaac ggccagcaac
    12601 ctggctaatg cctcaacgcc gggctttcgc gcgcagctta acgcgctacg cgcggtgccc
    12661 gttgatggcc tctctttagc gacgcgcacg ttggttacgg cgtcgacgcc gggggcggat
    12721 atgacccagg gtcagttgga ctacacttcc cgcccgctgg atgttgcgtt acagcaggac
    12781 ggctggctgg tggtgcaagc ggcggatggc gctgaaggat atacccgtaa cgggaatatc
    12841 caggtgggcc cgaccgggca gttaaccatt cagggacatc cggttatcgg cgaaggcggc
    12901 ccgattaccg ttccggaagg gtcggaaatc accattgcgg cagacggcac gatctccgcg
    12961 ctcaatcccg gcgacccgcc aaacacggtg gcgcccgttg ggcggctgaa gctggtcaaa
    13021 gcggaaggca atgaggtgca gcggagcgat gacggtttat tccgccttac cgccgaggca
    13081 caggctgaac gcggggcggt actggccgcc gacccgtcaa ttcgcattat gtcgggcgtg
    13141 ctggagggca gtaacgtcaa gccggttgaa gccatgaccg acatgatcgc caacgcacgt
    13201 cgttttgaaa tgcagatgaa ggttatcacc agcgtagatg agaacgaagg gcgagctaac
    13261 caactgctgt cgatgagtta atacaggaca ttttatgatc agttcattat ggatcgccaa
    13321 aaccggtctg gacgcgcagc aaaccaatat ggatgtgatt gccaataacc tggcaaacgt
    13381 cagcaccaat ggttttaagc gtcagcgcgc ggtatttgaa gatctgttgt atcagaccat
    13441 ccgccagccg ggcgcgcagt cgtccgagca gacgacgctg ccttccgggc tgcaaatcgg
    13501 taccggcgtg cgtccggtcg ccacggagcg cctgcacagt caggggaacc tgtcgcagac
    13561 caacaacagt aaagatgtgg cgattaaagg gcagggcttt ttccaggtca tgctgccgga
    13621 cggtacgtct gcctataccc gcgacggctc tttccaggtg gatcagaatg gtcaactggt
    13681 gacggcgggc ggttttcagg tgcagccggc aatcaccatt ccggccaacg cgttaagcat
    13741 cacgattggc cgcgacggcg tggtcagcgt tacccagcaa gggcaggccg cgccggttca
    13801 ggtcgggcag cttaacctga ccacctttat gaacgacacc ggtctggaaa gcatcggcga
    13861 gaacctctat atcgaaacgc aatcgtccgg cgcgccgaac gaaagcacgc cggggctcaa
    13921 cggcgcgggg ttgttgtatc aagggtatgt cgaaacgtcg aacgttaacg tggcggaaga
    13981 gctggtgaac atgattcagg ttcaacgcgc ctatgaaatt aacagtaaag cagtatcgac
    14041 gaccgatcag atgctgcaga aactgacgca actctaaggg gccgccggtg ggggatacgc
    14101 caccggctcc ctgattttga agatgaaggt aatgcaaaaa tacgcgcttc acgcttaccc
    14161 agttatggcc ctgatggtcg cgacgctgac aggatgcgcc tggatacccg ctaaaccgct
    14221 cgtgcagggg gcgaccacgg cgcagccgat acctggcccg gtaccggtgg cgaatggctc
    14281 catatttcag tctgcgcagc cgattaatta tggctatcag ccgctttttg aagatcgtcg
    14341 accgcgtaat atcggcgata cgctcacgat tgtgttacag gaaaacgtca gcgccagtaa
    14401 aagctcgtcg gcaaatgcca gccgcgacgg caaaaccagc tttggttttg atacggtacc
    14461 gcgttatctg cagggattat tcggtaattc ccgcgcggat atggaggcct ccggcggcaa
    14521 ctcttttaat ggtaaaggcg gcgcgaatgc cagcaatacc tttagcggca cgctgaccgt
    14581 gaccgtcgat caggttctgg ccaatggcaa tttacacgtc gtgggggaaa aacagatcgc
    14641 gattaatcag ggaacggaat tcatccgctt ctccggcgtg gtaaatccac gcaccatcag
    14701 cggtagcaac tctgttccct cgacacaggt ggcggatgcg cggattgaat atgtcgggaa
    14761 cggctatatt aacgaagcgc aaaatatggg ctggctgcaa cgtttcttcc ttaatttgtc
    14821 gccgatgtaa gcgaggtgta tgtgtttaaa gctcttgcag gaatcgttct ggcactggtt
    14881 gccactctgg cgcacgccga gcgtatccgg gatctgacca gtgtccaggg agtacgggaa
    14941 aactcgctga tcggctacgg gctggtggtc gggctggacg gtacgggcga ccagacgacc
    15001 cagacgccat ttaccaccca gacgctgaat aacatgctgt cacaactggg gattacggtc
    15061 cccaccggca ccaatatgca gttgaaaaac gtggcggcgg tgatggtgac ggcgtcgtat
    15121 ccgccttttg cgcgacaggg acaaacgatc gatgtcgtcg tttcctcaat ggggaacgct
    15181 aaaagtctgc gtggcgggac gttattaatg acgccgttaa aaggggtgga cagccaggtg
    15241 tatgctctgg cgcagggcaa tattctggtc ggcggcgcgg gcgcttccgc aggcggcagt
    15301 agcgtgcagg ttaaccagct taatggcggg cgcatcacta atggcgcgat tatcgaacgc
    15361 gagttgccga ctcagttcgg cgctggcaac accattaatc tgcaattgaa cgacgaagat
    15421 tttacgatgg cgcagcaaat taccgacgcc atcaaccgcg cccgcggtta cggcagcgcc
    15481 actgcgcttg atgcgcgaac ggtacaggta cgcgtgccca gcggcaacag ctcgcaggtg
    15541 cgttttctgg cggacattca aaatatggaa gtcaacgtga cgccgcagga tgcaaaagtc
    15601 gtgatcaact cgcgtaccgg ttcggtggtc atgaatcggg aagtcacgct ggatagctgc
    15661 gctgtggcgc agggcaattt gtcagtgaca gtcaatcgcc aactcaacgt caaccagccg
    15721 aatacgccat ttggcggcgg gcagaccgtg gtgacgccac agactcagat agatttgcgt
    15781 cagagcggcg gatcgctaca gagcgtgcgt tccagcgcca atctgaacag cgtagtgcgc
    15841 gcgctgaatg cgcttggcgc gacgccgatg gatctgatgt cgattttgca gtccatgcag
    15901 agcgcgggct gtctacgcgc caaactggaa atcatctgat gatcggagac ggtaaattgc
    15961 tggccagcgc ggcctgggat gcgcaatctc tgaacgaact gaaagcgaaa gcgggccagg
    16021 acccggcggc gaatatccgt cctgtggccc gtcaggtgga agggatgttt gtgcagatga
    16081 tgctgaaaag tatgcgcgag gctttaccca aagatggttt attcagcagc gatcagacgc
    16141 gtctgtatac cagcatgtat gaccagcaga tcgcccagca gatgaccgcc ggtaagggat
    16201 tggggctggc ggatatgatg gttaaacaga tgacgggcgg gcagacgatg cctgcagatg
    16261 atgcgccgca agtaccgctt aaattctccc tggagacggt aaacagctat caaaatcagg
    16321 cgctgaccca actggtgcgc aaagccatac cgaaaacgcc ggacagcagc gatgcgccgc
    16381 tctccggcga cagtaaagac tttctggccc ggctttcgct cccggcgagg ctggccagcg
    16441 aacaaagcgg ggtgccgcat catctgattc tggcgcaggc ggcgctggag tccggctggg
    16501 ggcagcggca aatcctgcgg gagaatggcg aacccagcta taacgtattt ggcgtgaaag
    16561 cgaccgccag ttggaaaggg ccggtgacgg aaatcaccac cactgaatac gaaaatggcg
    16621 aagcgaaaaa agtgaaagcg aaattccgcg tctatagctc gtatctggag gcgttatcgg
    16681 attatgtcgc gctgttaacg cgtaacccac gctacgctgc cgtgaccact gccgccacgg
    16741 cagagcaggg cgcagtggct ctgcaaaacg ccggatacgc cactgacccg aattacgcgc
    16801 gtaaattggc cagcatgatt cagcagttga aagcgatgag tgaaaaggtc agcaaaacct
    16861 acagcgcgaa tctcgacaat ctcttttaaa ttgctcaagt ccacgtagtc gctgccgata
    16921 acaacgagta ttgaaggatt aaaaggaacc atcatgtcca gcttgattaa tcacgccatg
    16981 agcggactta acgccgcgca ggccgcgtta aatacggtca gtaataacat caacaattat
    17041 aacgttgcgg gttatacccg gcagacaact attctggcgc aggcaaacag tacgttaggg
    17101 gctggcggct ggataggtaa tggcgtttac gtttcaggcg tacagcgcga atatgatgcg
    17161 tttatcacta atcagctacg cggcgcgcaa aaccagagca gcggcttaac cacgcgctat
    17221 gaacaaatgt cgaaaatcga caacctgctg gccgataaat ccagctcact gtctggctcg
    17281 ctgcagagtt tttttaccag cctgcaaacg ttagtcagta atgcggaaga tcctgcggcg
    17341 cgtcaggcgc tgattggtaa agcggaaggg ctggtaaacc agttcaaaac caccgatcag
    17401 tatctgcgcg atcaggataa acaggtcaat atcgcgattg gctccagcgt ggcgcaaatc
    17461 aacaattacg cgaagcagat agctaacctg aacgatcaaa tctcccgtat gacgggcgta
    17521 ggcgcgggcg catcgccgaa cgacctgctc gatcaacgtg atcagttggt tagcgagctt
    17581 aacaagatcg ttggcgtcga ggtgagtgta caggacggcg gcacctataa cctgacgatg
    17641 gccaatggct atacgctggt gcaggggtcg acggcgcgtc agttggcggc ggttccctcc
    17701 agcgccgacc cgacgcgaac gactgtcgct tatgtcgatg aggccgccgg taacatcgaa
    17761 attccggaaa agttgctgaa caccggttcg ctcggcgggc tactgacgtt ccgttctcag
    17821 gatctggatc agactcgtaa tacgctgggc cagttggcgt tggcgtttgc cgatgcgttt
    17881 aacgcgcagc ataccaaagg ttatgacgcc gacggcaata aagggaaaga cttctttagc
    17941 attggctcgc cggtggtata tagcaacagt aataatgccg ataaaacggt atcgctaacc
    18001 gctaaggtgg tcgacagcac gaaggttcag gcgacggatt ataagattgt ttttgacggt
    18061 acagactggc aggttactcg cactgcggat aacaccacct tcacggcaac aaaagatgct
    18121 gacggaaaac tggagattga cggtctgaaa gtgacggtag ggactggcgc acagaaaaac
    18181 gacagttttc ttctcaagcc ggtcagcaat gctatcgtcg acatgaacgt taaagtgaca
    18241 aatgaagccg agattgcgat ggcgtctgag tcaaaactcg atcctgatgt ggataccggc
    18301 gacagcgata accgcaatgg tcaggcattg ctggacttac aaaacagcaa tgtagtgggc
    18361 ggcaacaaaa cctttaacga tgcttacgcc acgttggtca gcgatgtggg taacaaaacg
    18421 tcaacgctga aaaccagcag caccacgcag gcgaatgtgg ttaaacagct ttataaacag
    18481 caacagtcgg tttccggcgt taacctcgac gaagagtacg gcaatttgca gcgttatcag
    18541 cagtattatc tggcgaatgc gcaagtattg cagaccgcga atgcgctgtt tgatgcgtta
    18601 ttgaatattc gctaaaggag aaggatgaca tgcgtatcag tacccagatg atgtacgaac
    18661 aaaatatgag cggcatcact aattctcagg ccgaatggat gaagctgggc gagcagatgt
    18721 ctaccggtaa gcgcgttacc aacccatctg acgatccgat cgccgcgtcg caggcggtag
    18781 tactctttca ggcgcaggcg cagaatagcc agtacgccct ggcgcgtacg tttgccaccc
    18841 aaaaagtgtc gctggaagaa agcgtactca gtcaggtgac gacggcgatt caaaccgcgc
    18901 aggaaaaaat cgtctatgcc ggaaacggca cgttaagcga cgatgaccgc gcgtcgctgg
    18961 cgacggattt acaggggatc cgcgatcagc tgatgaacct ggcaaacagc actgacggca
    19021 atggtcgcta tatctttgcc gggtataaaa cggaagcggc gccattcgac caggcgacag
    19081 gtggttatca tggcggcgag aaaagtgtta cccagcaggt ggattccgca cgcacgatgg
    19141 taattggcca tacgggagcg caaattttta atagcatcac cagcaatgcg gtgccggaac
    19201 cggatggctc ggactccgaa aagaatctgt ttgtcatgct cgatacggca attgccgcgc
    19261 tcaagacccc ggtggaaggc aatgacgtgg aaaaagaaaa agccgctgcc gccattgata
    19321 aaaccaatcg cggcttaaaa aattcgctta ataacgtcct gaccgttcgt gcggaactgg
    19381 gaacgcaact gagcgaactc agtacgctgg attcactggg aagcgaccgt gcgctgggac
    19441 agaagctaca gatgagcaac ctggtagatg tggactggaa ctcggtcatt tcctcctacg
    19501 tcatgcaaca ggcggcatta caggcgtcct ataaaacgtt taccgacatg cagggaatgt
    19561 cgcttttcca gttgaaccgg taacgcctct ttttgaaaca tatcacgaaa ctggatatgt
    19621 tttgtctgcc cgcgccatcc accccggcgc gggc
//
LOCUS       DAJVBX010000074        19565 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.074, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000074 DAJVBX010000000
VERSION     DAJVBX010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 19565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19565
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.074"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            70..519
                     /locus_tag="OPV72_002244"
     CDS             70..519
                     /locus_tag="OPV72_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCR9914526.1"
                     /translation="MKNTALGKFIFIVGTALLLGGCSGMVMPPYATHGTSVGIIAPAG
                     GYSEWHTDSRNHTTGDSHSQSQGNCTQSEDSQLSENGLTRTHQSNCNTRSQTHSSSTS
                     KTRSSSVGFSVGGPVGASIGLIKQMESMNRAPANDMSSNEMFKNFGF"
     gene            complement(655..780)
                     /locus_tag="OPV72_002245"
     CDS             complement(655..780)
                     /locus_tag="OPV72_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914527.1"
                     /translation="MKMHNDPHSMDSQSIFAGSQLLPMEKTSHLALSVGFRSHLA"
     gene            complement(1179..1976)
                     /locus_tag="OPV72_002246"
     CDS             complement(1179..1976)
                     /locus_tag="OPV72_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitermination protein"
                     /protein_id="HCR9914528.1"
                     /translation="MNLESLPKYFSPKSMMPGAVPCGITSDTLTITDVMASLGLLTAK
                     AAVGIELYLAKAGVLSSENIIAYIRQLAEQRAERHGALRKMEKGKRSKFLDTMARYVF
                     RDYSLSAASLVTCSSCHGAKLIDAEVFTNKVTYPDGKPPKWVKDTKGISPSDWEVWKS
                     VREQVRVVCKACDGKGQVKNECRCRGRGEILDKKKSELQGVPVYKKCPRCKGRGYPRL
                     KDTEIFKALGVTEMVWRYNYKLFFDRLVEHCHIEESYAEKVLGNVTR"
     gene            complement(1966..2112)
                     /locus_tag="OPV72_002247"
     CDS             complement(1966..2112)
                     /locus_tag="OPV72_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001617856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlcG family protein"
                     /protein_id="HCR9914529.1"
                     /translation="MKPELIEILRMRWLRLRIYRYRGSFPVAYRILRNYVRIEAKREH
                     RNES"
     gene            complement(2109..2720)
                     /locus_tag="OPV72_002248"
     CDS             complement(2109..2720)
                     /locus_tag="OPV72_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein NinG"
                     /protein_id="HCR9914530.1"
                     /translation="MAKLPRRKCANKECRQWFHPIREGQIVCSYQCASTVGKEQTRKA
                     REAAQRKAQSLQRAAEKKERAAWRQRKAAVKPLKHWIDLTQRAVNDICRETELAEGLG
                     CISCGTKTAFAWHAGHYRSTAAAGHLRFTRFNIHLQCDVCNVYKSGNIEAYRAALVER
                     YGEAAVLALENNNTPHRWTVEELKEIRLAALSDLRALKKLEAA"
     gene            complement(2929..3531)
                     /locus_tag="OPV72_002249"
     CDS             complement(2929..3531)
                     /locus_tag="OPV72_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1367 family protein"
                     /protein_id="HCR9914531.1"
                     /translation="MAHELQLIKQSSGILIPATPETSDILQSKIKLGAVLVAEFRQVR
                     NPAFHRRFFALLNLGFEYWEPTGGAISANERKLVNGYAKFLAAYGGNESALLDAAEQY
                     LEQIANRRVTNGISLCKSFDAYRAWVTVEAGHYDAIQLPDGTLRKHPRSIAFSSMDEV
                     EFQQLYKSALDVLWRWILSRTFRTQREAENAAAQLMSFAG"
     gene            complement(3866..4105)
                     /locus_tag="OPV72_002250"
     CDS             complement(3866..4105)
                     /locus_tag="OPV72_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001217670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinI family protein"
                     /protein_id="HCR9914532.1"
                     /translation="MRIELVISRTKQLPEGAVPALEKELITRLQNQYENCNLTIRRGS
                     QDGLSIVGAADGDKKRIQSILQETWESADDWFYAY"
     gene            complement(4290..4787)
                     /locus_tag="OPV72_002251"
     CDS             complement(4290..4787)
                     /locus_tag="OPV72_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000963896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HCR9914533.1"
                     /translation="MAIEYVEGVNYLSIEDIVYINRSLIEIQTPNEPIGVLNPNNLSS
                     SQSRPSTIRYYEQTDDMFRLSAVLIESLIQNHPFANANKRTAMMAGYVFLLLNGYELT
                     APSDEVVTIAEGLARKDYAVDDLENWLCHWSREYDSRTLCETGGNMIQALVATSRYIR
                     IKSNE"
     gene            complement(4798..4977)
                     /locus_tag="OPV72_002252"
     CDS             complement(4798..4977)
                     /locus_tag="OPV72_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016156674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914534.1"
                     /translation="MGHALKKADRLYIPPRDKSMVAKPRAAISKACSHTGQVKNAFEF
                     GFARYEKAMEELSKV"
     gene            complement(5823..6395)
                     /locus_tag="OPV72_002253"
     CDS             complement(5823..6395)
                     /locus_tag="OPV72_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001751779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF550 domain-containing protein"
                     /protein_id="HCR9914535.1"
                     /translation="MTTITKEWLQQTIAEFENTRDDIPFGLSDDDAKILIVLKRALAS
                     LEREQVRHEHADWSDATFGDVGPIGPLKHLSKEALETAAELGDLSEWADMQFLLWDAQ
                     RRAGITDEQIALAMVEKLAVNKKREWPEPKDGEPRLHIKEQPVPVVPEECPEEIRDLM
                     ASHSDALFNDDDAQEIWNACRAAMLNGGKS"
     gene            complement(6399..6872)
                     /locus_tag="OPV72_002254"
     CDS             complement(6399..6872)
                     /locus_tag="OPV72_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCR9914536.1"
                     /translation="MESQSILDMCCGSRMFWFNKRDERAVFADIRAEEHILCDGRRLV
                     ISPDLIADFRALPFADASFPVVVFDPPHLERVGQTAWMGKKYGRLNKKTWRSDLRAGF
                     KEAFRVLRAHGVLIFKWNETQIPVSQILALTDVKPIIGQRTGKNDKTHWIIFVKD"
     gene            complement(6872..7396)
                     /locus_tag="OPV72_002255"
     CDS             complement(6872..7396)
                     /locus_tag="OPV72_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ead/Ea22-like family protein"
                     /protein_id="HCR9914537.1"
                     /translation="MSNIDKRALREVAERATPGNWRRTSSLFNGITVTPFSLCGEEVT
                     LAHTVEKRDAEFIAAANPATMLALLDELETKEEQRANWFRMAQKLGEDLDTAERLIAE
                     LDQRLIEYAGIATREARRVAELEARKVNLSKLSVGEVMHMTGFSRDYAEGWCAGNDNA
                     IHEIRTAGIKVKES"
     gene            complement(7393..7740)
                     /locus_tag="OPV72_002256"
     CDS             complement(7393..7740)
                     /locus_tag="OPV72_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF977 family protein"
                     /protein_id="HCR9914538.1"
                     /translation="MARPKTHSERMIILERIIGLVKEQGRITTNDVVAIFGVHRTTAE
                     KYLRIALERGGFIRHGRCGIFRDQRAVIDYDLRRYSSSQVTGFSALPVLEKSPVMQVY
                     GASKMSINKGGAQ"
     gene            complement(7751..8500)
                     /locus_tag="OPV72_002257"
     CDS             complement(7751..8500)
                     /locus_tag="OPV72_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCR9914539.1"
                     /translation="MKNVIGTGSALDRLKRIIPASVQPKFSTADEWRAWQEAEGRKRS
                     EELDRMNQKSRTEKIFGRSGIQDLHRSCTFANYEVSGEGQRKAYTMAKSYAQNFGSGF
                     ASFVFSGGPGTGKNHLAAAIGNHLLAGGHSVLVVTIPDLMLRVRECYDGGQSEASLLD
                     DLCKVDLLVLDEVGIQRGSSGEKVILNQVIDRRLSSMRPVGVLTNLNHEGLLDSLGAR
                     VIDRLQMDGGMWVNFDWESYRKNVSHLRIVK"
     gene            complement(8503..9486)
                     /locus_tag="OPV72_002258"
     CDS             complement(8503..9486)
                     /locus_tag="OPV72_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HCR9914540.1"
                     /translation="MSMSNTAEIYKFPAPIPTQQECRMADLENGYLRLANQIQDALCI
                     VELSGREFRVLNAIIRLTYGWSKKSDRIANSLIADKTTLKVKHVSEAVLSLAYRNIII
                     LRRIGQTRYIGINTNLDKWAYSKPHCSKCPVSFPDDEIATWIISVPETRDSYTRKGGR
                     ASPKTGIVIPENRDSVLPHSAIPENGDSYPRKEGRASPKTGNTKDIIPKTNIKDLTPF
                     NPPKGKVKFDPLSIPVPEWLNAASWNEWVTYRQQSGKPIKTELTVTKAFRLLKECLDE
                     GHDPVNVINTSIANGYQGLFKPKFALNDRRAGRDVNHISAPDKTIPTGFRG"
     gene            complement(9571..9945)
                     /locus_tag="OPV72_002259"
     CDS             complement(9571..9945)
                     /locus_tag="OPV72_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914541.1"
                     /translation="MAYQAKRHQPNNHRGYLPMENAIARKLDPPEINPIEIESVLLNR
                     LASVGQKSYAEHMGISESTVSRRKAEGYFCNMAKELAFLGIQAAPPEAVLVSRNYLTA
                     VEILADAGLKAERARPDALGWD"
     gene            complement(9911..10147)
                     /locus_tag="OPV72_002260"
     CDS             complement(9911..10147)
                     /locus_tag="OPV72_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR9914542.1"
                     /translation="MKVTVQRKILSVCSQAGLGRRLGRRAQTVNGWFKNKVPGELVVR
                     VARAIDWKVTPHELRPDLYPNPTDGLPSQEASAK"
     gene            10277..10681
                     /locus_tag="OPV72_002261"
     CDS             10277..10681
                     /locus_tag="OPV72_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001009036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCR9914543.1"
                     /translation="MNFGERLQRVLNETGITQSELGRRVGATSQSVNGWCQSGILPRK
                     DILELLPKATGKPLYWFFMEDDDESDVPERLTQGGPTDLNDRQKRLLEIFDQLPTVEQ
                     DRFIELAGTRLQELDDFMAEYQRRRKIEPPSR"
     gene            10970..11170
                     /locus_tag="OPV72_002262"
     CDS             10970..11170
                     /locus_tag="OPV72_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HCR9914544.1"
                     /translation="MTNYGTTTLPRTSVVPGMLVKYQGRTYRASANVGKGLYLFTLFE
                     RLRTTNDEIEVYLNQHGKPATH"
     gene            11261..11557
                     /locus_tag="OPV72_002263"
     CDS             11261..11557
                     /locus_tag="OPV72_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001528639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host-nuclease inhibitor protein Gam"
                     /protein_id="HCR9914545.1"
                     /translation="MNAYLTYDRIEAQDWTRHYQQIAREEKESELADDLEKGLSLHML
                     ESLCMDELPRHGANKKAISRAFDDDVEFQERASEFVRYMAETFSRHQIDIESEE"
     gene            11563..12348
                     /gene="bet"
                     /locus_tag="OPV72_002264"
     CDS             11563..12348
                     /gene="bet"
                     /locus_tag="OPV72_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage recombination protein Bet"
                     /protein_id="HCR9914546.1"
                     /translation="MSTALATLAGKLAERVGMDSVDPQELITTLRQTAFKGDASDAQF
                     IALLIVANQYGLNPWTKEIYAFPDKQNGIVPVVGVDGWSRIINENQQFDGMDFEQDNE
                     SCTCRIYRKDRNHPICVTEWMDECRREPFKTRDGREITGPWQSHPKRMLRHKAMIQCA
                     RLAFGFAGIYDKDEAERIVENTTYTTDRQPERDITPVSDETMREINDLLITLNKTWDD
                     DLLPLCSQIFRRDIGASSDLTQIEAVKALGFLKQKAAEQKVEA"
     gene            12345..13025
                     /locus_tag="OPV72_002265"
     CDS             12345..13025
                     /locus_tag="OPV72_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqaJ viral recombinase family protein"
                     /protein_id="HCR9914547.1"
                     /translation="MTPEIILARTGIDVSNIEQGDDAWHRLRLGVITASEVHNVISRP
                     KSGKKWTDMKMSYFLTLLAEVCTGVAPEVNARALAWGKQYEDDARTLFEFTTDVKVTG
                     SPILFRDEDMRTACSPDGLCSDGRGLELKCPFTSRDFMKFRLGGFEAIKSAYMAQVQF
                     SMWVTGIDAWYFANYDPRMKREGIHHVVVERDDKYMSLFNEMVPEFIEKMDEALKEIG
                     FTFGEQWR"
     gene            13103..14167
                     /locus_tag="OPV72_002266"
     CDS             13103..14167
                     /locus_tag="OPV72_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001373762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DGQHR domain-containing protein"
                     /protein_id="HCR9914548.1"
                     /translation="MSKIGDYFFEFPASRGLQGNTVVLMMTVPARALTRVLASDNHGN
                     TLERSQRELNPARAKKFYEYLRTAYEKKEPFIIPPLVGNCDSFIEFEEFGNTNVGVAR
                     FPMDAEIKLFDGQHRAAGIAEFCRTYGEPIHIPMMLTHQLPLKTRQQFFSDINNNVSK
                     PSAAINMAYNGRDKIAQDMVSFLSSHAMFSEITDFEHNVVPAKSDLWISFKPLSDATA
                     KFSGNGDELATSDIYDIWEAWLKLTAIKGIRHGCTPVEYKRDYIQFHAVMINAFGYAM
                     QELLRHRPAHIIVQMIEELVNNSTMSELENFFLISSWSGVCASTEKDRATVIASVASQ
                     KAASVRLIQAITTKSFEVAA"
     gene            14164..15045
                     /locus_tag="OPV72_002267"
     CDS             14164..15045
                     /locus_tag="OPV72_002267"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010989138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Dam family site-specific
                     DNA-(adenine-N6)-methyltransferase"
                     /protein_id="HCR9914549.1"
                     /translation="MRYGSVCSGTAAMPIEEPALRTWRRPFLKWAGGKYSLLPELDRL
                     IPAGKRLIEPFVGGGSVFLNSDKHERFLLADVNADLINLYQMLAVVPDSVIAEAMKAF
                     RHLNDAENYTVIREAFNAQKLNATERAAAFLYLNRHCFNGLMRYNLDGFFNVGWGKYK
                     APYFPEEEIRAFRQKSHACVFMTAGFERTLRLAGDGDVVYCDPPYEPMPGTAGFTNYA
                     SGGFSWDSQVALAESCVAAHQRGAKVFISNSTAPRVIELYERHGFTLHRVNARRSISS
                     KGSTRETANDIVASLGI"
     gene            15051..15290
                     /locus_tag="OPV72_002268"
     CDS             15051..15290
                     /locus_tag="OPV72_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4060 family protein"
                     /protein_id="HCR9914550.1"
                     /translation="MKLINRSKQSPVGRRACDIALAAHHEKFGDYGRQKHVTNYTVVV
                     DGVKVPVEVVNRATSYVATAMIGVRKLRNLPAQAN"
     gene            15331..15579
                     /locus_tag="OPV72_002269"
     CDS             15331..15579
                     /locus_tag="OPV72_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase family protein"
                     /protein_id="HCR9914551.1"
                     /translation="MSNIIQLTPNKWVSEKVLIAVTGLKPGTITRARKESWMLGREYL
                     HISPDGNPKPSSECIYNREAVDQWIEAQKKNQPGAKTT"
     gene            15624..16916
                     /locus_tag="OPV72_002270"
     CDS             15624..16916
                     /locus_tag="OPV72_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3596 domain-containing protein"
                     /protein_id="HCR9914552.1"
                     /translation="MANASYPTGVENHGGSLRIWFLYKGKRVRENLGIPDTAKNRKIA
                     GELRSSVCFAIRMGNFNYVEKFPNSTNLARFGQDRKEITVLELTERWSELKRMEISSN
                     TMSRYESIIKNMLPLIGENKMVSAVTTEDLLYVRKELLTGFQVMKKDHRTQVKGRKSS
                     TVNNYMMLMAEIFQFGTDNGYAKENPFSGINRLKKAKGEPDPLTTDEFIRFIQACGHQ
                     QMRNLWSLAVYTGMRHGELCGLAWEDIDLHAGTIIVKRNLTQTDEFTLPKTDAGTDRV
                     IYLIQPAIDALRNQAQLTRLGRQFEVEVKLREYGQSVIQPCTFVFSPQCVKRGPRTGY
                     HYAVNSINKIWAPIIKRAGIRYRNAYQSRHTYACWSLSAGANPNFIATQMGHTDAQMV
                     YKVYGKWMSEKSAEQVSLLNQALSRYAPSLPQSMVAAQ"
     gene            17111..18313
                     /gene="pncB"
                     /locus_tag="OPV72_002271"
     CDS             17111..18313
                     /gene="pncB"
                     /locus_tag="OPV72_002271"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HCR9914553.1"
                     /translation="MTQFASPVLHSLLDTDAYKLHMQQAVFHHYYDVQVAAEFRCRGD
                     DLLGIYADAIREQVDAMQHLRLQEDEFQWLSGLPFFKPDYLNWLREFRYNPAQVCVTN
                     DNGKLNIRLTGSWREVIMWEVPLLAVISELVHHYRSPNAGVDQALDALESKLVDFTAL
                     TANLDMSRFHLMDFGTRRRFSREVQQAIVKRLQQESWFVGTSNYDLARRLALTPMGTQ
                     AHEWFQAHQQINPDLATSQRAALAAWLNEYPDQLGIALTDCITMDAFLRDFGIEFASR
                     YQGLRHDSGDPVAWGEKAIAHYEKLGIDPLTKTLVFSDNLDLPKAVELYRHFASRVQL
                     SFGIGTRLTCDIPQVKPLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALRKAFD
                     LPQVRKAS"
     gene            complement(18394..>19565)
                     /locus_tag="OPV72_002272"
     CDS             complement(18394..>19565)
                     /locus_tag="OPV72_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HCR9914554.1"
                     /translation="AGVAAAIAVGGPGAIFWMWIIAVVGMMTKMVEVTLAVKYRSKGE
                     NGEYYGGPMHYIKKELNKKWYPLAGLYAFALMILVITDACFVQTNTMAAVIHYTFDIP
                     TSVIGGFIVIVGALVILKGLASLGKFCTIALPPITIAYFIGAAGVVVLNIEAIPQVIK
                     SIFYYAFAPAPAAGGFVGSTIMMAISKGASRGIFTNEAGMGTSATVHATANVDYAFRQ
                     GMWGAVEVFFVSMITCNFTAFAVLASGMWTDASYQGIQIIFAALKETWHPIIVQVLCL
                     GVALILFTSYLGSYIKFRTSINYIFGDKLERIIKWLYFLPPLIAVNMEIPVIWLMADI
                     AVGFLVIPNVIALFLLRKEFISEFNLFRTRTQRDTNSEKTTQITHVNMSKSEGEE"
BASE COUNT         4957 a         5005 c         4744 g         4859 t
ORIGIN      
        1 atgaataata gcgagccctg ccaaggcagg gcatagaaat aaccaacgag aagaaatagg
       61 taggaactaa tgaaaaacac cgctctgggt aagttcattt ttatcgtcgg caccgcgtta
      121 ctgctcggtg gctgtagtgg catggtcatg cctccctatg ccacccacgg tacatcggtc
      181 ggaatcattg cgccggcggg aggctatagc gagtggcaca cggatagccg caaccacacc
      241 acaggagaca gtcacagcca gtcacaggga aactgcaccc aaagtgaaga tagccagctc
      301 agcgaaaatg gtctcacacg gacacaccaa agcaactgta acacccgtag tcaaacccac
      361 agcagtagca ccagcaaaac ccgctccagc agcgtcggtt tcagcgtcgg ggggcctgtt
      421 ggtgctagca tagggttgat caagcagatg gagtcgatga accgtgcgcc agccaacgat
      481 atgagtagta atgagatgtt caagaatttc ggtttctagc acataacgcc acctggtacc
      541 gttgtggtgt ctggcccggc ggctatctgt aacgactcac aatcgaaaaa agtcagactc
      601 gcaatcagcg caaattttgg ctcacaataa ctgcaactga aatcggacgt ggactcacgc
      661 taagtgagag cgaaatccga cgctcagagc caaatgagaa gttttttcca ttggcagtaa
      721 ttgtgagcca gcaaaaatag attgtgagtc cattgaatgg ggatcgttgt gcattttcat
      781 aagcctcacc tccgatagct cggatggcgc agtgtgaagt aggaaggccg cccggtggat
      841 caacgacaaa gctcagaggg attattccgg acggcacaaa cagaaaagcc ccggcaatca
      901 ccgaggctta aattgttgcc ggttaccgct ccggcgcgat cagcaaaagc tatcgcggta
      961 tcagattgtg gtcctgcccg tgtgagcttt gcggtcggct ggaacatgta gactccgcat
     1021 cactccccgc actttgtctt attggcgtcg ggaatccata aaagaaaacc ccgccgaggc
     1081 gaggttctta attcttgtaa cgtcacaggc gtaataaccc atcgttggaa tcaggttagc
     1141 cattttccgt taattttgca atagctaaat tattttggtc atcgagtcac gtttcccaga
     1201 accttttctg catacgactc ctcaatatgg caatgctcca ccagtcgatc gaaaaacagt
     1261 ttatagttgt accgccatac catttccgtt actcctagtg ctttaaaaat ctcggtatct
     1321 ttgagacgtg ggtagcctct tcccttgcat cttgggcatt ttttataaac cggcacgccc
     1381 tgcaactcag attttttctt atcgagaatt tctccgcgtc cccggcaacg acattcattt
     1441 ttcacctggc ctttgccatc acacgcctta cacactacgc gcacctgctc acgaactgat
     1501 ttccacacct cccagtcgga cggagaaata cctttcgtat cttttaccca ttttggtggc
     1561 ttaccatccg ggtaagtaac cttgttcgtg aaaacctcag catcaattaa tttagcacca
     1621 tgacagctac tgcacgtcac caagctggcc gcactgaggg aataatcgcg aaatacataa
     1681 cgcgccatag tgtcgagaaa ttttgagcgc ttaccctttt ccattttccg taatgcccca
     1741 tgccgttctg cacgctgctc tgctaattgc ctgatgtagg cgatgatatt ttcagaagat
     1801 aaaaccccgg cttttgccag atacaattca atacccactg cggcttttgc agtaagtagc
     1861 ccgagagatg ccattacgtc agtaatagtc agcgtatcag acgttattcc gcatggtact
     1921 gcgccgggca tcatggattt aggtgaaaaa tatttcggta aggactcaag attcatttcg
     1981 atgctcccgt tttgcttcaa tgcggacgta attacgaaga atgcggtatg ccacaggaaa
     2041 agatccccgg tatcgataaa ttcggagacg caaccagcgc atgcggagta tctcgatcag
     2101 ttctggtttc atgcggcctc cagctttttt agcgcacgca gatccgacag tgccgcgagc
     2161 ctgatttcct tcagctcctc gaccgtccag cggtgcgggg tgttattgtt ctcgagtgcc
     2221 agcaccgccg cctcaccgta acgctcaacc agcgcggcac gatatgcttc gatgttccct
     2281 gatttgtaga cgttgcagac atcacactga agatggatgt tgaagcgagt gaagcgcaga
     2341 tgcccggcgg cggccgtact cctgtaatgg cctgcatgcc atgcgaatgc cgtcttcgtt
     2401 ccacaggaga tgcaaccgag tccttctgcc agttcggttt cgcggcaaat gtcatttacg
     2461 gcgcgctgcg tcaagtcaat ccagtgtttc agcggcttaa ccgcggcttt ccgctggcgc
     2521 caggcggcgc gttctttttt ctcagcggcg cgctgaaggg attgcgcctt acgttgcgcg
     2581 gcttcgcgag cttttctggt ctgttctttg ccgacggtgc tggcgcactg gtacgagcaa
     2641 acgatctgcc cctctcgtat cgggtgaaac cactggcggc attctttgtt tgcgcactta
     2701 cggcgcggta atttagccat gttcaccccc agaccttttg gcgtaaggat tttggcgtcc
     2761 gcacccggtg tgcatattct ggtaatttcg cgctgacagt ccaggtaatg aagtcagggt
     2821 tcaggctctt ttctgtcctt acgccccgct tctgataatc cgatatcagc gtgtcggcct
     2881 gctcggttgt gcagtcgtga tgatggaacc aggagtattt catcgccatc accccgcaaa
     2941 gctcatgagc tgggcggcgg cgttctccgc ctcgcgctga gtacgaaatg tacgtgataa
     3001 aatccaccgc cagagcacat caagcgcgga tttatacaac tgctgaaatt cgacctcatc
     3061 catgctggaa aaagcgatgc tgcggggatg tttgcgaagg gtgccgtccg gtaactggat
     3121 ggcgtcatag tgaccagcct caaccgtcac ccatgcgcgg tatgcatcga aagatttaca
     3181 gaggctaatt ccgtttgtta cccggcggtt tgcaatctgt tccagatact gttcagccgc
     3241 atccagtaat gcgctttcat tcccgccata tgcagcgaga aactttgcat aaccgtttac
     3301 cagtttgcgc tcattggcag aaatggcgcc gccggtgggt tcccagtatt caaacccaag
     3361 attaagcaac gcgaaaaagc ggcgatggaa tgcaggattc ctcacctgac ggaactcagc
     3421 caccagcacg gcgccgagtt tgatttttga ttgcagaata tcactggtct ccggcgttgc
     3481 ggggatcaga attccagatg actgcttgat gagttgtaat tcgtgcgcca tggcgttctc
     3541 cgtggcgcag caggtgcagg ttgttcaggc ctacatttga agtgtatcaa agcaacgggt
     3601 aattcgatag cctgcctttt ctaacatttg cgtaaataat gttggagttc caactatgtc
     3661 atcagggtga aggggaacaa aagatatctc gtcaccacga cgatacatca gggcgcgtcc
     3721 gctatccgga atactaccga accttgccac tacacaatga tcgtaacaac gtataaccgc
     3781 ataccctgat tctggtaagt cttctaacat gtaacccccc gtcacactga ctttatttct
     3841 ggaaacgtct gcgactccac gatgcttaat atgcataaaa ccagtcgtca gcgctttccc
     3901 acgtttcctg cagaatgctc tgtatacgtt ttttatcgcc atcagcagca ccgacgatac
     3961 tcagaccatc ctgactgcct cgacggatgg ttaagttgca gttttcatac tgattctgga
     4021 gacgggtaat taattctttt tcaagtgcag gcacggcacc ttccggaagc tgttttgtcc
     4081 ggctgataac aagttcaatt ctcataattc cctctacatt taactactgt atataaacac
     4141 agtatacctg ttagaaagaa tattcaagag gtgaatagca ctttttgcaa aagccatgcc
     4201 attgtatagg aagagttttt cctagtattc ggaatttact aaatcagtta ggcaaaggct
     4261 gaaagcgaaa aaaaacccgc cgtagcgggt tattcattcg atttgattcg gatgtaacgt
     4321 gaggtcgcca cgagagcctg aatcatatta ccgccagttt cgcataacgt tctggaatca
     4381 tactcgcgtg accagtggca taaccaattt tccaggtcat ccactgcgta atctttacga
     4441 gccaaaccct ctgcgatggt tacaacttca tcactaggtg ctgtaagctc atatccgttc
     4501 agcaacagga atacgtaacc tgccatcata gcggtgcgtt tgtttgcgtt tgcgaatgga
     4561 tgattctgga ttaggctttc aattagaaca gcagacagac gaaacatatc gtctgtctgc
     4621 tcataatatc gaatggtgct tggccgggac tgggaagaac tgaggttgtt cggattcagt
     4681 acgcctatcg gttcatttgg cgtctgaatc tcgatcagag acctgttgat gtaaacgata
     4741 tcttcaatgg aaagataatt gactccttca acatactcta tcgccatccg tttttactca
     4801 gacctttgaa agttcttcca tcgccttctc gtaacgagca aacccaaact caaaggcgtt
     4861 tttaacttga ccagtatgtg aacatgcttt gctgatcgct gcacgaggtt tcgccaccat
     4921 ggatttgtca cgaggcggaa tgtacaagcg atctgccttt tttaatgcgt gacccatgat
     4981 tatcaccctc atgcacgttt ggcagtgctt tctcaaattg taggatgtaa acacatccaa
     5041 agaatttatg atcactttaa gtggttgagg acaatttaat accattcgtc atatttgagc
     5101 aatgggcctg cgtctgaaga tagaagcatg ttcgacgaaa atctcaatgg ccactttgca
     5161 agttaacgac attttcgcag aagttacccc tcaggtaata gtaaactatt gtcacgatct
     5221 caggagatag gctggtcctg tgagtcgatt aaagtggaca caaagccaat aaatagcact
     5281 ttttgcacaa aaatcatatc ctggttggaa tgcacaacgc ccaacattgc tgtagtattt
     5341 cgccccctct gaatgtagcg ctcagatttt aatcgaccca atcccgccct gcttcaacat
     5401 caagccccgc atatgcgagg cttgttgggc taacccgccg cagcgggtta tgacgcaaca
     5461 cttcatgccg gagttttccg atccgtcttg ttgtgaacct cccagagact aatgccgcaa
     5521 ctgaacacaa actcagccag ataatttaaa ccggaccatt cccggatgcc gccgcgcgcc
     5581 gcttccacaa atacagcgat atcctgatca cgccacactc caaacaggcg ccagccgcca
     5641 ctgtcagtct taacggctgc tatacgcgtc agaacaccag tctggtacag gtcagtgaac
     5701 gcaggtttct tcctggttat tattcgcata tctacaaacc taagaaatgt tgattacaaa
     5761 tcactgattc gtattttttg attttgcact aatgccgatc acaggaccgg catataggtg
     5821 tttcacgatt tacctccgtt gagcatggca gcgcgacaag cgttccagat ttcttgcgca
     5881 tcgtcgtcgt tgaaaagcgc atcagaatgt gaagccatca ggtcgcgtat ttcttccgga
     5941 cattcttccg gcactaccgg cactggctgc tctttgatat gcagtcgtgg ctcgccgtct
     6001 ttcggttcag gccattcgcg cttcttgttc accgccagct tttccaccat cgccagggca
     6061 atctgctcgt cagtaatacc agcgcggcgt tgtgcatccc ataacaggaa ttgcatatca
     6121 gcccattcgc tcaggtcgcc aagttctgcg gcagtttcca atgcttcttt tgagaggtgc
     6181 ttcagtggac cgatggggcc aacatcgccg aatgtggcat cagaccagtc agcatgttca
     6241 tggcgaactt gttctcgttc cagcgatgcc agcgcacgct tcagcacaat aagaattttg
     6301 gcgtcgtcat cgctcaggcc aaacggaata tcatcgcgag tgttttcaaa ttcagcgatg
     6361 gtttgctgta gccattcttt ggtaatagtg gtcatgggtt agtccttcac aaaaataatc
     6421 cagtgggttt tatcgttctt gccggtgcgc tggccaataa ttggtttcac gtcagtaagc
     6481 gccaaaatct ggctaaccgg aatctgcgtt tcgttccatt tgaaaatgag aacgccgtgt
     6541 gccctcagca cccgaaacgc ctctttgaat ccggcgcgga ggtcagaacg ccatgttttt
     6601 ttgttgagtc tcccgtactt tttgcccatc caggccgttt ggccgacacg ttccaggtga
     6661 ggcggatcaa acaccacgac cggaaacgac gcatcagcga acggtagcgc acgaaaatca
     6721 gcaatgaggt caggactgat gactaggcgg cgaccgtcgc acaatatatg ctcctcggcg
     6781 cggatatcgg cgaatacggc gcgttcatcg cgcttattaa accaaaacat gcgcgagccg
     6841 cagcacatat ccagaataga ttgcgattcc atcacgactc cttaaccttg atgccagcgg
     6901 tgcgtatttc gtgtatcgca ttatcattac cagcacacca accctcggca taatcccggc
     6961 tgaatccggt catgtgcatg acttctccaa cgctgagttt tgacaggttg accttccgcg
     7021 cctccagttc tgccacccgg cgagcctcac gggttgcaat tcccgcgtat tcaatcaggc
     7081 gttggtccag ttcggctatg aggcgttctg ctgtatccaa atcctcgcct aacttctgcg
     7141 ccatccgaaa ccaattggcg cgctgttcct ctttggtttc cagctcatcc agcagcgcca
     7201 gcatggtggc ggggttggct gcggcgataa attccgcgtc acgtttctca acagtatggg
     7261 ccaacgtcac ttcttcaccg caaagagaaa atggcgttac cgtgatgcca ttgaacagtg
     7321 atgaggtgcg gcgccaattc cccggcgtag ccctctcagc cacttcacga agcgcccgtt
     7381 tgtcgatgtt gctcattggg ctcccccctt gttgatgctc attttggatg ctccataaac
     7441 ctgcattacc gggcttttct ccagcaccgg cagcgctgaa aatcccgtta cctgactact
     7501 gctgtatcgc ctgaggtcat aatcaatcac cgcacgctgg tctcggaaaa tgccgcagcg
     7561 gccatgacga atgaagccgc ctcgctccag cgcgatacgc agatatttct ccgccgtggt
     7621 tcggtgcacg ccaaaaatcg caacgacgtc gttcgtcgtg atgcgcccct gctctttcac
     7681 cagaccgata atccgctcaa gaataatcat ccgttcgctg tgtgttttag gtcgggccat
     7741 ttttaacccc ttatttcaca atccggaggt ggctaacgtt tttccggtag ctttcccagt
     7801 caaaattcac ccacatccct ccgtccatct ggaggcgatc gataaccctc gcgcccagtg
     7861 aatccaacag cccctcgtgg ttaagattcg tcagaacgcc aacaggtcgc atcgatgaga
     7921 gacggcgatc gataacctga ttgagaatga ccttctcacc actgctcccg cgctgaatac
     7981 cgacttcatc cagtaccagc aggtcaactt tgcaaaggtc atcaagcagg gacgcttctg
     8041 attgcccacc gtcgtagcac tcacgaaccc tgagcatcag gtcaggaatg gttaccacca
     8101 gaacgctatg accgccggcc agcagatgat ttccgattgc cgccgcaaga tggtttttcc
     8161 cggttcccgg accaccgctg aacacaaagc tcgcaaatcc actaccgaag ttctgggcat
     8221 aactttttgc catcgtgtac gcttttcgct gcccctcccc gcttacttcg tagttagcaa
     8281 acgtacagct acgatggaga tcctgaatgc cagatcgccc gaaaatcttc tcggtgcggg
     8341 atttctgatt catcctgtca agctcttcac tgcgtttacg cccttcggct tcctgccatg
     8401 cccgccactc atcagcagtc gagaatttcg gctgcacact ggctgggata attcttttca
     8461 ggcgatcaag cgcactgcca gtaccgatta cgtttttcat cgttaccccc tgaatccggt
     8521 aggaatggtt ttgtctggcg cagaaatgtg gttcacatct ctgccagctc ttcggtcgtt
     8581 gagagcgaac ttcggtttga atagtccctg gtagccgttg gcaatgcttg tgttgatgac
     8641 gtttaccgga tcgtggcctt catccaggca ctccttcaga agcctgaaag cttttgttac
     8701 cgtcagttcg gtttttatgg gctttccgga ttgctggcgg tatgtgaccc attcgttcca
     8761 cgacgcagca ttcagccatt cgggaacagg aatactcaac ggatcaaact tcacttttcc
     8821 cttaggggga ttaaaggggg ttagatcttt tatatttgtc tttggaataa tgtctttggt
     8881 gttccctgtt ttcggggatg cccttccctc ttttcgggga taactatccc cgttttcagg
     8941 gatggctgaa tggggtaaaa cgctatccct gttttcaggg ataactatcc ccgttttcgg
     9001 ggatgccctt cccccttttc gggtataact atccctggtt tcgggtacag aaataatcca
     9061 tgtggcaatt tcatcatcag gaaaagacac cggacatttt gagcaatgtg gcttggaata
     9121 agcccattta tccaggtttg tattaatccc tatgtatctt gtttgaccaa tacggcgcag
     9181 gataatgatg ttacgatagg caagactcag caccgcttcg gatacatgct ttaccttcag
     9241 tgttgtctta tctgcaatga ggctgttggc aatacgatct gattttttcg accagccata
     9301 agtcagccgg ataatcgcat tcaaaacacg gaactcacgc cccgatagtt caacgataca
     9361 caaggcgtcc tggatctgat tagctaaacg taaatagcca ttttccagat cagccatacg
     9421 gcactcctgt tgcgtcggta tcggcgcagg gaatttgtat atttcagcgg tatttgacat
     9481 actcatctcc gcaattacct accgtttttg caccagaaag ccgttggtga cccctcaccg
     9541 cggctttcgc ctttttggtt gctgtcattt tcagtcccac cccagcgcat ccggcctggc
     9601 tcgttcagcc tttagcccgg catcagcgag aatctctacg gctgtgagat agtttctgga
     9661 taccagtacc gcttccggtg gcgcggcctg aatcccaaga aaagccagct ctttcgccat
     9721 gttgcagaaa tatccctcag ctttacgcct gctgactgtc gactcgctga tgcccatatg
     9781 ctcggcgtat gatttctgcc ctactgatgc aagccggttg agcaggacac tctctatctc
     9841 aatcgggttg atttctggtg ggtctaactt tcgtgcaatt gcgttctcca tgggtaaata
     9901 tcctctatgg ttatttggct gatgcctctt ggcttggtaa gccatcggtt gggtttgggt
     9961 agagatcagg acgcagttcg tgtggggtga ctttccagtc aatagctctt gccactcgaa
    10021 ctacaagttc gccgggaact ttgtttttaa accagccgtt aacggtctga gcacggcgac
    10081 caagtcggcg tcccaaccca gcctggctac acacggaaag gatcttgcgt tgaacagtta
    10141 ctttcattgg tcggtctcat tgagtgaaga tacaaccaat tattcaaatt taatcgatac
    10201 tgtcaaatta tttcgataga catacctaca gaaaaaatct gtataatgaa accatgtaat
    10261 tgtgcgagaa cgaaaaatga actttggaga gcgtttacaa agagtgctta atgagactgg
    10321 gatcacccaa tctgagttag gtcgtagagt cggcgctacc tctcaatcag ttaatggttg
    10381 gtgtcagtcc ggcattcttc cccgaaaaga tatcttagag ttgttaccta aggccacggg
    10441 taagccgttg tattggttct tcatggagga tgatgatgaa tcggatgtgc ctgaacgtct
    10501 aacacaaggt ggtccaacag atctcaatga ccgacaaaag cggctcttag aaatatttga
    10561 tcagctaccg actgttgaac aagaccgttt tattgagctg gcaggcacca gacttcaaga
    10621 actagacgat ttcatggctg aataccaaag acgcagaaaa atcgagcctc cttctcgcta
    10681 aaccagcttt aaaactacta accgccttaa ctggcggttt ttttatgtca ttaattcacc
    10741 cacatctcgc tttcttaatc ttccctgtaa aattaatcat caaatttaat tgacatgtat
    10801 cgattgaatc gataatactt aacctatcaa ccgcagcaac gagtcatcaa ggcaggacgc
    10861 ccacgaagta gccgcccggg gcatacgaag accgggatga gatggcaagg ttaacgcgca
    10921 gcaggtgata aacgttccgc tggccggcga taaggcaaac gagggtgaga tgactaatta
    10981 cggcacaaca acattaccaa gaaccagcgt tgtaccggga atgctggtta agtaccaggg
    11041 gcgcacatac cgcgcatctg caaacgtagg aaaagggttg tacttgttta cccttttcga
    11101 acgcctgcgg acaaccaacg acgagatcga ggtttacctc aaccaacacg gcaaacctgc
    11161 aacccattag caggaaaaac cagcaaaacg aaatactgca cagattctgg cagaccacat
    11221 ggtgtcgggg attctgcaaa ccaaattcag gagttcagcc atgaacgcat atctcactta
    11281 cgaccggatc gaggctcagg actggacccg gcattaccag caaatcgcca gagaagagaa
    11341 agagtcagaa cttgctgacg atctggagaa aggactgtcg cttcacatgc tggagtcgct
    11401 gtgtatggac gagctaccac gccacggcgc caacaaaaaa gcgatcagcc gggcatttga
    11461 tgacgatgtc gaattccagg agcgcgcgtc ggagtttgtg cggtacatgg ccgagacgtt
    11521 ttcccggcat caaattgata ttgaatcaga ggaataagac aaatgagcac agcactcgca
    11581 acactggcag gaaaactggc tgaacgtgta ggaatggatt ctgtagatcc gcaggaactg
    11641 atcactacat tgcgccagac agcgtttaaa ggtgatgcca gtgatgcgca gtttattgcg
    11701 ttactgatag tcgccaacca gtacggtctt aatccgtgga cgaaagaaat ttacgccttt
    11761 cctgataagc agaacgggat cgtccctgtg gtgggcgttg atggctggtc ccgtatcatc
    11821 aacgaaaacc agcagtttga cggtatggat tttgagcagg ataacgaatc atgtacatgc
    11881 aggatttacc gtaaggaccg taaccatccg atctgcgtta ccgaatggat ggatgaatgt
    11941 cgccgggaac cattcaaaac ccgtgatggt cgtgagatta ctggaccgtg gcagtcacat
    12001 cccaaacgga tgttgcgaca caaagcaatg atccagtgcg cccgtcttgc cttcggtttc
    12061 gcaggtatct acgacaagga tgaggccgaa cgcattgtcg aaaataccac gtataccaca
    12121 gatcgccagc cggaacgcga catcactccg gttagcgatg aaaccatgcg ggaaattaat
    12181 gatctgctga tcaccctgaa taaaacatgg gatgacgatc tgctgccgct ctgctcccaa
    12241 atcttccgtc gcgatattgg tgcatcgtca gatcttacgc aaatcgaagc agtgaaagcc
    12301 ctcggattcc tgaagcagaa agcagcagaa cagaaggtgg aagcatgaca ccagaaatta
    12361 tcctggctcg tacaggtatt gacgttagca acatcgagca aggtgatgac gcgtggcacc
    12421 gtctacgcct cggtgtcatc actgcttccg aagttcacaa cgtcatttcc aggccaaagt
    12481 cgggcaagaa gtggactgat atgaagatgt cctactttct cacccttctt gccgaagttt
    12541 gcaccggcgt ggcaccggaa gttaacgcca gggcgctggc ctgggggaaa cagtatgaag
    12601 atgatgcccg caccctgttt gagttcacca ctgacgtgaa agtcaccggg tcgccgatcc
    12661 ttttccgtga cgaggacatg cgtaccgcct gttctcctga cggcctgtgc agtgatggcc
    12721 gcggtcttga gttgaaatgc cctttcacct ctcgcgactt tatgaaattc aggcttggcg
    12781 gcttcgaggc tatcaaatcc gcctatatgg cccaggtgca attcagcatg tgggtaaccg
    12841 ggatagatgc ctggtatttc gcgaattatg acccgcgcat gaagcgagaa ggcattcacc
    12901 acgtggttgt tgagcgcgac gacaaataca tgtccctctt caatgaaatg gtaccggaat
    12961 ttatcgaaaa gatggacgaa gcgctaaagg agattggctt cacgttcggg gagcagtggc
    13021 gatgacgcac gcacaggacg aaatcagggt tggcgcgatg cgccatccca tgttgaagaa
    13081 ttaaatgtta gaggacggaa gtatgagcaa aattggtgac tatttctttg aattcccggc
    13141 atcaagaggc ttacagggaa atacggttgt gttgatgatg acagtcccag cgcgcgcgct
    13201 aactcgcgtt ctggcatcag ataaccacgg caatacgctt gagcgttctc agcgagaact
    13261 caatccagcg cgtgcgaaga agttttatga atacctgcga acagcttacg agaaaaaaga
    13321 gccgttcatc atcccgccgc tggttggaaa ctgcgactca ttcattgagt tcgaagagtt
    13381 tggcaatacg aatgtgggtg tcgcgcgatt cccaatggat gcggaaatta aactgtttga
    13441 cggtcagcat cgcgccgcag gcattgcaga gttctgccgc acttacggag agcctattca
    13501 catcccaatg atgctgacac accaactgcc gctcaaaacg cgccagcagt tcttttccga
    13561 catcaacaac aacgtatcga agccatcagc ggccatcaat atggcctata acggtaggga
    13621 taaaattgct caggatatgg tttcgttttt gtcatcccat gccatgttct cagaaataac
    13681 agactttgaa cacaacgtgg ttccggcgaa aagcgatctc tggattagct tcaaacccct
    13741 gagtgatgca actgcaaaat tctctggtaa tggggatgag cttgctacta gtgacatcta
    13801 tgacatttgg gaggcatggc tcaagctaac agccatcaag ggaattaggc atggttgtac
    13861 gcctgttgaa tataagcggg attacatcca gttccacgcg gtgatgatca atgcgtttgg
    13921 ctacgcaatg caggaactac tacggcatcg ccctgcacac atcattgttc agatgattga
    13981 ggagttagta aataattcca ctatgagtga gctggagaat ttcttcctca tttcatcctg
    14041 gtccggtgtc tgcgccagca ctgaaaaaga tagagcgaca gttattgcca gcgttgcttc
    14101 acaaaaagct gcttcggtga gactaatcca agctattacg acaaagagct ttgaggtcgc
    14161 agcatgagat acggctctgt ttgcagtgga actgcggcga tgcccataga ggaaccggcg
    14221 ctgcgcacct ggcgccgccc gttcctgaaa tgggcaggcg gtaaatattc gctgctgccg
    14281 gaactggatc gtcttatccc ggcaggtaaa cgactgatag agccatttgt gggcggcgga
    14341 tcggtgtttc ttaactcaga caagcacgaa cgcttccttc tggctgacgt caacgctgac
    14401 ctgattaacc tgtaccagat gctggccgta gtgcctgatt cggtaatcgc agaggctatg
    14461 aaagctttca gacatctgaa tgatgccgaa aactacacag taattcgtga agcattcaac
    14521 gcccagaaac tgaatgcgac agaacgagcg gccgcattcc tttacctcaa caggcactgc
    14581 tttaacggtc tgatgcgtta caaccttgac ggttttttca atgttggatg gggaaagtat
    14641 aaagccccat atttcccgga agaagagatc agggcattca ggcagaagtc tcacgcgtgc
    14701 gtatttatga ctgcgggttt cgaacgtact ctcaggctgg cgggtgatgg tgatgtcgtt
    14761 tactgcgatc cgccatacga gccaatgccc ggcaccgctg gcttcactaa ctacgcctcc
    14821 ggtgggttct catgggatag ccaggtagcg cttgctgaaa gctgtgtggc agcccatcag
    14881 cgtggcgcaa aggtgtttat cagtaattct accgcaccac gcgttattga actttacgag
    14941 aggcacggct tcactctgca ccgggtcaat gcccgcagat caatatcgag taaaggcagt
    15001 acccgagaaa cagcgaacga tatcgtcgcc tcactgggga tttagtgatg atgaaactta
    15061 ttaacagaag taagcaatca ccagtcggtc gtcgcgcatg tgatattgca ctggctgcgc
    15121 atcatgagaa gttcggcgat tacggcagac aaaagcacgt taccaattac accgttgtag
    15181 tggatggcgt aaaggttcct gtcgaagtag ttaaccgggc caccagctac gtagccaccg
    15241 caatgatcgg cgtccggaaa cttagaaatc tgccagcaca ggcaaactga atattagcga
    15301 tggcccgctg cggggccact ggagaaaacg atgagcaaca ttatccaact gacgccaaac
    15361 aagtgggtta gcgaaaaagt tctgattgcg gttaccgggc ttaagcccgg aaccattacc
    15421 cgcgccagaa aagaatcctg gatgctgggc cgcgagtacc tgcacatttc accagacgga
    15481 aatccgaagc cttcgagcga atgcatatac aacagagaag ccgttgatca gtggatcgag
    15541 gcgcagaaaa aaaatcaacc aggtgcgaag acaacatgaa aagcagtaca ctcgtcaatg
    15601 ctcctggacg tcaggaggga ttaatggcta atgcatcata cccgacaggc gtcgaaaacc
    15661 acggcggttc gctccgcatc tggtttctgt ataaaggtaa acgtgtcagg gaaaaccttg
    15721 gtatccctga cactgcaaaa aatcgcaaga tagctggcga actgcgttct tcggtttgtt
    15781 ttgcgataag gatggggaat tttaactatg tggaaaaatt cccaaactca acgaaccttg
    15841 cccggttcgg tcaggataga aaggaaatta ctgtgctgga gcttaccgaa agatggtccg
    15901 agctgaagag aatggagatc agctctaata ccatgagtag gtacgaatct atcataaaaa
    15961 acatgcttcc actcatcggc gaaaacaaaa tggtttctgc ggtgactact gaggatttgc
    16021 tgtatgtcag gaaggagttg ctgacgggct ttcaggtaat gaagaaggat caccggactc
    16081 aggttaaagg ccggaaatcg tccacagtga ataattacat gatgctgatg gccgagatct
    16141 tccagtttgg aacagataac ggctatgcaa aggaaaaccc gtttagcgga attaaccgtc
    16201 tcaagaaagc gaaaggggaa ccagatccac tcacgacaga cgagttcatc aggtttatcc
    16261 aggcatgcgg ccaccagcag atgagaaatc tctggtcact ggcagtctat accggaatga
    16321 ggcatgggga gttgtgcggt ctggcctggg aagatatcga tctgcatgcc gggacgatca
    16381 ttgtgaagcg caaccttacc cagacggatg agttcaccct gccaaaaacc gacgcaggta
    16441 ctgacagggt gatatatctc attcaaccag ctattgatgc cctgaggaat caggcccagt
    16501 tgacacgcct tggccggcag tttgaggttg aagtgaagtt gcgggaatat ggacaatctg
    16561 tcattcagcc ctgcacgttc gtattcagcc ctcaatgcgt caaacgtgga cctcgcacag
    16621 gatatcacta cgcggttaat tccattaata aaatttgggc cccgataatc aagcgtgccg
    16681 gcattcgtta ccgtaacgcg tatcagtcac gacataccta tgcatgctgg tcattatcag
    16741 ctggtgctaa cccaaacttt atagcaacgc agatggggca taccgatgca cagatggttt
    16801 acaaggtgta tggaaagtgg atgtcagaga agagcgcaga acaggtttct ctgctcaacc
    16861 aggcactttc ccgctatgcc ccatcactgc cccaaagcat ggtagcagcg cagtagaaat
    16921 ccttaaattc aaggggttag cagtcgcatc gctacatttt tataacatgg ggcacgaaat
    16981 gcgctcgacc ctaaagacag cttatggtgt gatcggggtt caataaatcg ctaaacaagg
    17041 tatactccag cggttttctt agttgtttat tgtactaaac actcccgtga gaggacgcaa
    17101 cagcgcacct atgacacaat tcgcttctcc tgttctgcac tcgttgctgg atacagatgc
    17161 ttataagttg catatgcagc aagccgtttt tcaccactac tatgatgtgc aggtagcggc
    17221 tgagtttcgt tgccgtggcg acgacctgct gggtatttat gccgatgcta ttcgcgagca
    17281 ggtggacgcg atgcagcacc tgcgcctcca ggaggacgag ttccagtggc tctccggcct
    17341 gccctttttt aaaccggatt atctgaactg gttacgcgag tttcgctata acccagctca
    17401 agtctgtgtc accaacgata acggcaagct gaatattcgc ttaaccggct cgtggcgtga
    17461 agtcattatg tgggaagtgc cgctgctggc cgtgatcagt gagctggttc atcactaccg
    17521 ctcgccaaac gcgggcgttg atcaggcgct cgacgcgctg gaaagtaagc tggttgattt
    17581 cactgcgtta accgccaatc tcgatatgtc ccgcttccac ctgatggact tcggcacccg
    17641 ccgccgtttc tctcgtgaag tgcagcaggc gatagttaaa cgtctccagc aggagtcatg
    17701 gttcgtcggc accagcaact atgatctcgc gcgtcgcctg gcgctgacgc cgatgggcac
    17761 tcaggcgcac gaatggttcc aggcgcatca acaaatcaat ccggacctgg cgaccagtca
    17821 gcgtgccgcg ttggccgcct ggcttaacga atatccggac cagcttggta tcgcattgac
    17881 agattgcatt acaatggatg cgtttttacg cgatttcggc attgaattcg ccagccgtta
    17941 tcaggggtta cgccacgact caggagaccc tgtcgcatgg ggcgaaaagg cgattgccca
    18001 ttatgaaaag ctggggattg atccgctgac aaaaacgctg gtcttttcag ataaccttga
    18061 tctgccaaag gcggtcgagc tctatcgcca tttcgcctct cgcgtgcagt taagcttcgg
    18121 catcggtacc cgactgacct gcgatatccc tcaggtaaaa ccgctcaata tcgtgattaa
    18181 gctcgtggaa tgtaacggaa agccggtggc taaactttcc gacagccccg gtaaaacgat
    18241 ctgtcatgat aaagcgtttg tgcgcgcgct gcgtaaagcg ttcgatctcc cgcaggtgcg
    18301 taaagcaagt taaccatgcc tgtgcgaagc gcccggaaag tgggcgcttt gttactcttc
    18361 tgaccatctt acctgttctg gccgcgatgg tgactattct tccccttcac tcttcgacat
    18421 atttacgtgc gtgatttgcg ttgttttttc agaattagtg tcccgctgtg tacgcgttct
    18481 gaataaattg aattcgctaa taaattcttt acgcagcaag aacagagcaa ttacgttggg
    18541 gataaccaga aaaccgacag caatatcagc cattaaccag attaccggga tttccatatt
    18601 aacggcaatc agtggcggca aaaaatatag ccatttaatg atgcgttcta gcttatcgcc
    18661 aaagatatag tttattgaag tgcgaaattt aatatatgaa ccaagataag aagtaaacag
    18721 aatcaacgcc acaccgagac agagaacctg aacaataatc ggatgccatg tttcttttaa
    18781 ggcggcaaag ataatctgaa taccttgata actggcgtct gtccacatac cagaagcaag
    18841 tacagcaaat gcggtaaagt tacaggtaat cattgaaaca aaaaatactt ccactgcccc
    18901 ccacattccc tgacggaaag cataatccac gttggcagta gcatgtactg tggccgaggt
    18961 acccatgccg gcttcgttag tgaatattcc gcgactggct cctttactga tggccatcat
    19021 gatggttgac ccgacaaagc caccggctgc tggcgcaggg gcaaaggcat aatagaaaat
    19081 actttttata acctgtggga tagcctcgat attcaatacc actacaccag cggcaccaat
    19141 gaaataggca atggtgatcg gtggaagtgc aatcgtacag aatttaccaa gactggcgag
    19201 tccttttaaa ataaccaacg cgcctacgat gacaataaat cccccaatga cgcttgttgg
    19261 gatgtcaaac gtatagtgaa tgaccgccgc catcgtatta gtttgcacaa aacaggcatc
    19321 cgtaataacc agaatcatta atgcaaacgc atataatcct gccaggggat accatttttt
    19381 attgagctct ttcttaatat aatgcattgg gccgccataa tattcgccat tctcaccttt
    19441 acttcggtat ttcaccgcca gcgtcacttc aaccattttg gtcatcatac ccacgaccgc
    19501 aatgatccac atccagaaaa ttgccccagg tccgccaacc gcaatagccg cagcaacacc
    19561 tgcga
//
LOCUS       DAJVBX010000075        18683 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.075, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000075 DAJVBX010000000
VERSION     DAJVBX010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 18683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18683
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.075"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            116..1522
                     /gene="gndA"
                     /locus_tag="OPV72_002273"
     CDS             116..1522
                     /gene="gndA"
                     /locus_tag="OPV72_002273"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HCR9914555.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSVFNRSREKTEEVIA
                     ENPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLEKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKDAYELVAPILTKIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLSNEELANT
                     FTEWNNGELSSYLIDITKDIFTKKDEDGNYLIDVILDEAANKGTGKWTSQSALDLGEP
                     LSLITESVFARYISSLKAQRVAASKVLSGPKAQPAGDKAEFIEKVRRALYLGKIVSYA
                     QGFSQLRAASDEYHWELNYGEIAKIFRAGCIIRAQFLQKITDAYAENAGIANLLLAPY
                     FKKIADEYQQALRDVVAYAVQNGIPVPTFSAAVAYYDSYRAAVLPANLIQAQRDYFGA
                     HTYKRTDKEGIFHTEWLE"
     gene            1759..2925
                     /gene="ugd"
                     /locus_tag="OPV72_002274"
     CDS             1759..2925
                     /gene="ugd"
                     /locus_tag="OPV72_002274"
                     /EC_number="1.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="HCR9914556.1"
                     /translation="MKITISGTGYVGLSNGLLIAQHHDVVALDIVPARVELLNDRISP
                     IVDKEIQQFLKEDNIRFRATLDKFDAYQNADYVIIATPTDYDPKTNYFNTFSVESVIQ
                     DVISINPAAVMIIKSTVPVGFTAAMRQKFATENIIFSPEFLREGKALYDNLYPSRIVI
                     GEQSERAREFAALLQEGAIKQEIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYA
                     ETLGLNTRQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYQSVPNNIISAI
                     VEANRTRKDFIADSILARKPKVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVII
                     YEPVMQEETFFNSRLERDLHCFKQQADVIISNRMAAELLDVAEKVYTRDLFGSD"
     gene            3068..4051
                     /gene="wzzB"
                     /locus_tag="OPV72_002275"
     CDS             3068..4051
                     /gene="wzzB"
                     /locus_tag="OPV72_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS O-antigen chain length determinant protein
                     WzzB"
                     /protein_id="HCR9914557.1"
                     /translation="MTVDSNASSGRGNDPEQIDLIELLLQLWRGKMTIIVAVIIAILL
                     AVGYLMIAKEKWTSTAIITQPDAAQVATYTNALNVLYGGNAPKISEVQANFISRFSSA
                     FSALSEALDNQKEREKLTIEQSVKGQTLPLSVSYVSTTAEGAQRRLAEYIQQVDEEVA
                     KELEVDLKDNITLQTKTLQESLETQEVVAQEQKDLRIKQIEEALRYADEAKITQPQIQ
                     QTQDVTQDTMFLLGSDALKSMIQNEATRPLVFSPAYYQTKQTLLDIKNLKVTADTVHV
                     YRYVMKPTLPVRRDSPKTAITLVLAVLLGGMIGAGIVLGRNALRSYKPKAL"
     gene            complement(4132..4743)
                     /locus_tag="OPV72_002276"
     CDS             complement(4132..4743)
                     /locus_tag="OPV72_002276"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="HCR9914558.1"
                     /translation="MLTEQQRRELDWEKTDGLMPAIVQHAVSGEVLTLGYMNPQALDK
                     TIESGHVTFFSRTKQRLWTKGETSGHVLNVVSIAPDCDNDTLLVLANPVGPTCHKGTS
                     SCFGDASHQWLFLYQLEQLLAERKTADPASSYTAKLYASGTKRIAQKVGEEGVETALA
                     ATVNDRFELTNEASDLMYHLLVLLQDQDLNLTTVIDDLRKRHQ"
     gene            complement(4737..5513)
                     /gene="hisF"
                     /locus_tag="OPV72_002277"
     CDS             complement(4737..5513)
                     /gene="hisF"
                     /locus_tag="OPV72_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HCR9914559.1"
                     /translation="MLAKRIIPCLDVRDGQVVKGVQFRNHEIIGDIVPLAKRYADEGA
                     DELVFYDITASSDGRVVDKSWVARVAEVIDIPFCVAGGIRSIDDAAKILSFGADKISI
                     NSPALADPTLITRLADRFGVQCIVVGIDTWFDDATGKYHVNQYTGDENRTRVTQWETL
                     DWVQEVQQRGAGEIVLNMMNQDGVRNGYDLTQLKKVRDVCRVPLIASGGAGTMEHFLE
                     AFRDADVDGALAASVFHKQIINIGELKAYLAGQGVEIRIC"
     gene            complement(5495..6232)
                     /gene="hisA"
                     /locus_tag="OPV72_002278"
     CDS             complement(5495..6232)
                     /gene="hisA"
                     /locus_tag="OPV72_002278"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HCR9914560.1"
                     /translation="MIIPALDLIDGTVVRLHQGDYARQRDYGNDPLPRLQDYAAQGAG
                     VLHLVDLTGAKDPAKRQIPLIKTLVAGVNVPVQVGGGVRTEEDVAALLKAGVARVVIG
                     STAVKSPDVVKGWFERFGAQALVLALDVRIDEHGNKQVAVSGWQENSGVSLEQLVETY
                     LPVGLKHVLCTDISRDGTLAGSNVSLYEEICARYPQIAFQSSGGIGDIDDIAALRGTG
                     VRGVIVGRALLEGKFTVKEAIQCWQNV"
     gene            complement(6232..6822)
                     /gene="hisH"
                     /locus_tag="OPV72_002279"
     CDS             complement(6232..6822)
                     /gene="hisH"
                     /locus_tag="OPV72_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005128083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HCR9914561.1"
                     /translation="MNVVILDTGCANLSSVKSAVARHGYTPVVSREAEIVLRADKLFL
                     PGVGTAQAAMDQLRERELIDLIKACTQPVLGICLGMQLLGRRSEETRGVDLLNIIEQD
                     VPKMTDFGLPLPHMGWNRVYPQAGNRLFQGIEDGAYFYFVHSYAMPVNPWTIAQCNYG
                     EPFTAAVQKDNFFGVQFHPERSGAAGAQLLKNFLEM"
     gene            complement(6822..7889)
                     /gene="hisB"
                     /locus_tag="OPV72_002280"
     CDS             complement(6822..7889)
                     /gene="hisB"
                     /locus_tag="OPV72_002280"
                     /EC_number="3.1.3.15"
                     /EC_number="4.2.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     histidinol-phosphatase/imidazoleglycerol-phosphate
                     dehydratase HisB"
                     /protein_id="HCR9914562.1"
                     /translation="MSQKYLFIDRDGTLISEPPSDFQVDHFDKLAFEPEVIPVLLKLQ
                     KAGFKLVMITNQDGLGTQSFPQADFDGPHNLMMQIFTSQGVCFDEVLICPHLPADDCD
                     CRKPKVKLVERYLAEQAMDSANSYVIGDRATDIQLADNMGITGLRYHRETLNWTMIGE
                     QLTKRDRYAHVVRNTKETQIDVSVWLDREGNSKINTGVGFFDHMLDQIATHGGFRMEI
                     TVKGDLYIDDHHTVEDTGLALGEALKLALGDKRGICRFGFVLPMDECLARCALDISGR
                     PHLEYKAEFTYQRVGDLSTEMIEHFFRSLSYTMGVTLHLKTKGKNDHHRVESLFKAFG
                     RTLRQAIRVEGDTLPSSKGVL"
     gene            complement(7886..8965)
                     /gene="hisC"
                     /locus_tag="OPV72_002281"
     CDS             complement(7886..8965)
                     /gene="hisC"
                     /locus_tag="OPV72_002281"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HCR9914563.1"
                     /translation="MSTENTLSVADLARENVRNLVPYQSARRLGGNGDVWLNANEFPT
                     AVEFQLTQQTLNRYPECQPKAVIENYAQYAGVKPEQVLVSRGADEGIELVIRAFCEPG
                     KDAILYCPPTYGMYSVSAETIGVERRTVPALENWQLDLQGISDNLDGAKVVFVCSPNN
                     PTGQLINPQDLRTLLELTRGKAIVVADEAYIEFCPQATLAGWLVKYPHLVILRTLSKA
                     FALAGLRCGFTLANEEVINLLLKVIAPYPLSTPVADIAAQALSPQGINVMRDRVAQTV
                     QERQYLVNALQQTACVEHVFDSETNYILARFTASSSVFKSLWDQGIILRDQNKQPSLS
                     GCLRITVGTRQENQRVIDALRAEPV"
     gene            complement(8962..10266)
                     /gene="hisD"
                     /locus_tag="OPV72_002282"
     CDS             complement(8962..10266)
                     /gene="hisD"
                     /locus_tag="OPV72_002282"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HCR9914564.1"
                     /translation="MSFNTLIDWNSCSPEQQRALLTRPAISAFDSITRTVSDILYNVK
                     TRGDDALREYSAKFDKTEVTALRVTPEEIAAAGARLSDELKQAMAAAVKNIETFHSAQ
                     TLPPVDVETQPGVRCQQVTRPVASVGLYIPGGSAPLFSTVLMLATPARIAGCQKVVLC
                     SPPPIADEILYAAQLCGVQEIFNVGGAQAIAALAFGSESVPKVDKIFGPGNAFVTEAK
                     RQVSQRLDGAAIDMPAGPSEVLVIADSGATPDFVASDLLSQAEHGPDSQVILLTPDAD
                     IARKVAEAVERQLAELPRAGTARQALSASRLIVTKDLAQCVAISNQYGPEHLIIQTRN
                     ARDLVDAITSAGSVFLGDWSPESAGDYASGTNHVLPTYGYTATCSSLGLADFQKRMTV
                     QELSKAGFSALASTIETLAAAERLTAHKNAVTLRVNALKEQA"
     gene            complement(10369..11268)
                     /gene="hisG"
                     /locus_tag="OPV72_002283"
     CDS             complement(10369..11268)
                     /gene="hisG"
                     /locus_tag="OPV72_002283"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005128078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HCR9914565.1"
                     /translation="MLDNTRLRIAIQKSGRLSDDSRELLARCGIKINLHTQRLIAMAE
                     NMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYLTLRRLDFG
                     GCRLSLATPVDEAWDGPAALDGKRIATSYPHLLKRYLDQKGVSFKSCLLNGSVEVAPR
                     AGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMAQSKQQLIDKLLTRIQ
                     GVIQARESKYIMMHAPSERLEEVIALLPGAERPTILPLAGEQQRVAMHMVSSETLFWE
                     TMEKLKALGASSILVLPIEKMME"
     misc_feature    complement(11316..11439)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00514"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="His leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF00514"
     gene            complement(11415..11456)
                     /gene="hisL"
                     /locus_tag="OPV72_002284"
     CDS             complement(11415..11456)
                     /gene="hisL"
                     /locus_tag="OPV72_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002231208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="his operon leader peptide"
                     /protein_id="HCR9914566.1"
                     /translation="MTRVQFKHHHHPD"
     gene            11619..12443
                     /locus_tag="OPV72_002285"
     CDS             11619..12443
                     /locus_tag="OPV72_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCR9914567.1"
                     /translation="MKKVAIVGLGWLGMPLAMSLAARGWQVTGSKTTLDGVEAARMSG
                     IESYPLRLEPELVCEADDLDALLDVDALVITLPARRSGPGEDFYLQAMQELVDSALAY
                     RIPRIIFTSSTSVYGDAQGVVKENTPRNPVTASGRTLKELEDWLHNLPGTSVDILRLA
                     GLVGPGRHPGRFFAGKTAPDGQHGVNLVHLEDVVGAITLLLQAPKGGHIYNICAPAHP
                     ARNVFYPQMTRLLGMAPPHFRDAPDNGKGKIIDGSRICNELGFEYQYPDPLVMPME"
     gene            12489..13403
                     /locus_tag="OPV72_002286"
     CDS             12489..13403
                     /locus_tag="OPV72_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCR9914568.1"
                     /translation="MKPLLDVLIILDALEKEGSFAAASAKLFKTPSALSYTVHKLEND
                     LNIQLLDRSGHRARFTRTGKMLLEKGREVLHTVRELEKQAIKLHEGWENELVIGVDDT
                     FPFSLLAPLIDAFYQRHSVTRLKFVNGVLGGSWETLTQGRADIIVGAMRAPPPDTGFG
                     FARLGDLELVFAVAPHHPLVHEEEPLSRQTIKRFRAIVVGDSVHSSRSIGSELLDAQE
                     AITVFDFKTKLELQISGLGCGYLPRYLAQRFLESGALIEKKVVAQIVYEPVWVGWNEQ
                     TAGLASGWWRDEILANNAIAGVYAKSPV"
     gene            13637..13699
                     /gene="yoeI"
                     /locus_tag="OPV72_002287"
     CDS             13637..13699
                     /gene="yoeI"
                     /locus_tag="OPV72_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein YoeI"
                     /protein_id="HCR9914569.1"
                     /translation="MGQFFAYATAFAVKENDHVA"
     gene            13689..15047
                     /gene="plaP"
                     /locus_tag="OPV72_002288"
     CDS             13689..15047
                     /gene="plaP"
                     /locus_tag="OPV72_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416518.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine/proton symporter PlaP"
                     /protein_id="HCR9914570.1"
                     /translation="MSHNVTPNTSRVELRKTLTLVPVVMMGLAYMQPMTLFDTFGIVS
                     GLTDGHVPTAYAFALIAILFTALSYGKLVRRYPSAGSAYTYAQKSISPTVGFMVGWSS
                     LLDYLFAPMINILLAKIYFEALVPSIPSWVFVVALVAFMTAFNLRSLKSVANFNTVIV
                     VLQVVLIAVILGMVVYGVFEGEGAGTLASTRPFWSGDAHVIPMITGATILCFSFTGFD
                     GISNLSEETKDAERVIPRAIFLTALIGGLIFIFATYFLQLYFPDISRFKDPDASQPEI
                     MLYVAGKTFQVGALIFSTITVLASGMAAHAGVARLMYVMGRDGVFPKSFFGYVHPKWR
                     TPAMNIILVGAIALLAINFDLVMATALINFGALVAFTFVNLSVISQFWIREKRNKTLK
                     DHFQYLFLPMCGALTVGALWVNLEESSMVLGLIWAGIGLIYLACVTKSFRNPVPQYED
                     VA"
     gene            complement(15183..16613)
                     /gene="sbcB"
                     /locus_tag="OPV72_002289"
     CDS             complement(15183..16613)
                     /gene="sbcB"
                     /locus_tag="OPV72_002289"
                     /EC_number="3.1.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease I"
                     /protein_id="HCR9914571.1"
                     /translation="MTVKNDSIQSTFLFHDYETFGTHPALDRPAQFAALRTDNDFNVI
                     GEPEVFYCKPADDYLPQPGAVLITGITPQEAREKGENEAAFARRIHALFTVPKTCVVG
                     YNNVRFDDEVTRNIFYRNFYDPYAWSWQHDNSRWDLLDVMRACYALRPEGINWPENDD
                     GLPSFRLEHLTQANGIEHSNAHDAMADVYATIAMAQLVKTRQPRLFDYLYSHRSKHKL
                     AALIDVPQMKPLVHVSGMFGAWRGNTSWVAPLAWHPENRNAVIMVDLAGDISPLLELD
                     SDTLRERLYTAKADLGDHAAVPVKLVHINKCPVLAQANTLRPEDADRLGINRQHCLDN
                     LKVLRENPQVRDKVVAIFAEAEPFATSDNVDAQLYDGFFSDADRAAMKIVLETEPRNL
                     PALDITFVDKRIEKLLFNYRARNFPGTLDDAEQQRWLEHRRQVLTPEFLQQYANELQM
                     LSQQYAEDKTKLGLLKSLWQYATEIV"
     gene            complement(16980..18683)
                     /locus_tag="OPV72_002290"
                     /pseudo
     CDS             complement(16980..18683)
                     /locus_tag="OPV72_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461011.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="type III secretion system effector HECT-type E3
                     ubiquitin transferase"
BASE COUNT         4323 a         4760 c         4990 g         4610 t
ORIGIN      
        1 aatctgaacg catcaatcgc taccttaata tcataccttt gagttaacat actattcacc
       61 tttaacctgc catgaccgtt tgtggcaggg tttccacacc tgacaggagt atgtaatgtc
      121 caagcaacag atcggcgtcg tcggtatggc agtgatgggg cgcaacctcg cgctcaacat
      181 cgaaagccgt ggttataccg tctccgtttt caaccgctcc cgtgaaaaga ccgaagaagt
      241 gattgccgag aatcccggca aaaagctggt gccttattac acggtgaaag agtttgttga
      301 atccctcgaa acgcctcgtc gtatcctgtt aatggtgaaa gcgggtgcag gtactgatgc
      361 agctatcgat tcgctgaaac cgtatctgga aaaaggcgat atcattattg atggcggtaa
      421 caccttcttc caggacacaa tccgtcgcaa tcgcgagctg tctgcggaag gttttaactt
      481 tatcggtacc ggtgtttccg gtggtgaaga gggcgcgctg aaagggccat ctatcatgcc
      541 tggcggtcag aaagatgcct atgaactggt ggcgccgatc ctgacgaaga ttgctgctgt
      601 ggcagaagat ggcgaaccgt gcgtgaccta tatcggcgcc gatggcgcgg gtcactacgt
      661 taagatggtc cacaatggta ttgaatatgg cgatatgcag cttatcgctg aagcttactc
      721 cttgctgaaa ggcggcctga atctcagcaa tgaagagttg gcgaacactt ttactgagtg
      781 gaataacggc gagctgagca gttatctgat cgacatcact aaagacatct tcactaaaaa
      841 agatgaagac ggtaattact tgatagatgt tattcttgat gaagccgcca acaaagggac
      901 cggtaaatgg accagccaga gcgcgctgga tctgggcgaa ccgctgtcgc tgattaccga
      961 atccgtcttt gcgcgttaca tctcttcgct gaaagcgcaa cgtgttgccg catctaaagt
     1021 gctctccggg ccgaaagcgc agccggcggg cgacaaagcg gaatttatcg agaaagtgcg
     1081 tcgcgcgctg tatcttggca agatcgtctc ctatgcgcag ggcttctcgc agctacgcgc
     1141 cgcgtctgat gaatatcact gggagcttaa ctacggcgag attgctaaga ttttccgtgc
     1201 gggctgtatc attcgcgctc agttcctgca gaagatcacc gatgcttacg cagaaaacgc
     1261 cggtatcgct aacttgctgt tagcgcctta cttcaagaaa attgctgatg agtaccagca
     1321 ggcgctgcgt gatgttgtgg cttacgcggt gcagaatggc attccggtgc cgacattctc
     1381 tgcggcagtg gcctactatg acagctatcg cgccgcagta ctgccagcta acttaattca
     1441 ggcgcagcgt gactactttg gtgcgcacac ctataaacgt actgataaag aaggcatttt
     1501 ccataccgag tggttggaat aatttctgca agcttgttta agcccggttt aatactgggc
     1561 ttttttttat ctctattctt attgatttat cgcttttgct taatattaac ttaataatct
     1621 gtgtttatcg taatgaagat aatctgaatt gttttcgtct gcgttgcact ttatatactc
     1681 aggcgttaaa actttgatat cttatcagga tgcgaaatac atcatgattc ataattaagt
     1741 taattctgag agcgaataat gaaaatcacg atatccggga cgggttatgt tggcttgtct
     1801 aatggtttgc ttattgcaca acaccatgat gtggtggcgt tagacattgt tcctgcccgt
     1861 gttgaactgt taaatgatcg gatatctccg attgttgata aagaaattca gcaattttta
     1921 aaggaagata acatcagatt cagggcaacg ctggataagt ttgatgcata ccagaatgca
     1981 gattacgtca tcattgctac gcctacagat tacgatccaa aaaccaacta ttttaatacg
     2041 ttcagtgtag aatcggtcat tcaggatgtg atcagcatca accccgcagc cgtgatgatt
     2101 attaagtcta cggtgccggt tggctttacg gcggcaatgc gtcagaagtt tgcgacagaa
     2161 aatatcattt tctctccgga atttttacgt gaaggtaaag ccctttacga taacctttat
     2221 ccctcccgta tcgtgattgg ggaacagtct gagcgcgccc gagaatttgc cgcattactc
     2281 caggaaggcg ctattaaaca ggagattccg acgctgttta cggactccac tgaagcggaa
     2341 gccattaaac ttttcgccaa tacttacctc gccatgcgag tcgcttattt taatgaatta
     2401 gacagttatg ctgaaacgtt aggattaaat acccgacaaa ttattgaagg ggtgtgcctc
     2461 gacccgcgta ttggcaatca ttacaataat ccctcttttg gttatggcgg atattgtttg
     2521 ccaaaagata ccaaacagtt gctggctaat tatcagtcag tgcctaataa tattatctcc
     2581 gctatcgttg aagcaaaccg tacgcgtaaa gattttattg ccgattctat ccttgccaga
     2641 aagcctaaag tggtgggcat ttatcgcctg attatgaaga gtggctccga taacttccgc
     2701 gcctcatcga ttcaggggat tatgaaacgt attaaagcga aaggcgtaga ggtcatcatc
     2761 tatgagccgg taatgcaaga agaaactttc tttaactcac gtcttgaacg tgatttgcac
     2821 tgctttaaac agcaggcgga tgtcattatt tccaatcgga tggcggcaga gcttttggat
     2881 gtcgctgaaa aagtgtatac ccgcgatctt ttcggtagtg attaataagg caatcggggc
     2941 tgatgagtcc cgatgattta ttgaccaaat ggaaataatg tctgattttt atcattaatc
     3001 ctatggcata tattttcttt atgactacac tgtctccagc ttcatccttt ttttagttag
     3061 ggtatctatg acagtggata gtaatgcgtc ttccgggcgt gggaacgatc cggaacagat
     3121 tgatttgatt gagttattgc tacagttatg gcgtgggaag atgaccatta ttgtagccgt
     3181 tattatcgcc attttgctgg ccgtaggcta cctgatgata gccaaagaaa aatggacatc
     3241 cacggcgatt attacccaac ctgatgccgc gcaggttgcc acctatacca acgcgctcaa
     3301 cgtcttgtat ggcgggaatg cccccaaaat ctctgaagtg caggcgaatt ttataagccg
     3361 ctttagttct gcgttttccg cattatcgga agcgctggat aatcagaaag agcgggaaaa
     3421 gctcaccatt gaacagtcgg taaaggggca gacgctgccg ctctcggttt cttatgtgag
     3481 cactaccgct gaaggggcgc agcgtcggct ggcggaatat atccaacagg tggatgaaga
     3541 ggtcgctaag gaactggaag ttgacctgaa agataacatc acgctgcaaa ccaaaacgtt
     3601 gcaggagtcc cttgagacgc aggaagttgt ggcgcaggag caaaaagatc tgcgtattaa
     3661 gcaaatcgaa gaagcgttgc gctatgcgga tgaggccaaa atcacgcagc cgcagattca
     3721 gcaaacccag gatgttaccc aggacacgat gttcctgttg gggagcgatg cgctaaaatc
     3781 gatgatacag aacgaagcga cgcgtccact ggtcttttct ccggcctatt accagacgaa
     3841 gcagacactg ctggacatta aaaatctgaa agtgactgcc gatacggtgc acgtctatcg
     3901 ttatgtgatg aagccgacgc tgccggtccg tcgcgatagc ccgaaaacag ccattaccct
     3961 cgtgctggct gtgttgctgg gcgggatgat cggcgccggg attgtgctgg ggcgcaatgc
     4021 gctacgtagc tataagccaa aagccttgta agcttctttg ccggatggtg gtcggcttcg
     4081 aaaggtaaaa tttctcatta aaaaaccggg cattgcccgg tttttttacg cttattgatg
     4141 acgcttacga agatcgtcga tcacggtggt gaggttgaga tcctgatcct gcaacagcac
     4201 cagcaggtgg tacatcaaat cagacgcttc attggttaat tcaaaacgat cattgacggt
     4261 ggccgccagc gcggtttcta caccttcttc gccaactttt tgcgcaatac gtttggtacc
     4321 gctggcgtac agtttcgccg tgtaagagct ggccggatcg gcggttttgc gctctgccag
     4381 tagctgctcc agttgataca ggaataacca ctgatggctg gcgtcgccaa agcagctgct
     4441 ggtacctttg tggcaggtcg gcccgacagg gtttgccagc accagcagtg tatcgttgtc
     4501 gcaatctggc gcaatgctga cgacattcag cacatggcct gaggtttcgc ctttggtcca
     4561 taaacgctgt ttcgtgcgtg agaagaacgt gacatggccg gattcaatgg ttttgtccag
     4621 cgcttgtggg ttcatatagc ccagcgtcaa tacttcgccg gataccgcat gttgcacgat
     4681 ggctggcatc aggccatcgg ttttttccca gtccagctcg cggcgttgtt gctctgttaa
     4741 catatcctga tctccacgcc ctggcctgcc aggtacgctt ttaattcgcc aatattgatg
     4801 atttgcttgt gaaaaacgga ggcggcaagc gcgccgtcga catcggcatc acggaatgcc
     4861 tcaagaaagt gttccatcgt gcccgcgccg ccggaggcga tcagcggcac gcggcaaacg
     4921 tcacggactt ttttcaactg cgtcagatca taaccgttac gcacgccgtc ctggttcatc
     4981 atattcagga cgatttcccc cgcgccgcgc tgttgtacct cttgcaccca gtccagcgtc
     5041 tcccactgcg tcacgcgggt acggttttca tcgccggtat actggttaac atgatatttc
     5101 cccgtggcgt cgtcaaacca ggtatcaatc ccgacgacaa tgcactgcac gccaaaacgg
     5161 tcagccagac gggtaatcag cgttgggtca gccagtgcag gggagttgat agagatctta
     5221 tccgccccga aagagagaat tttggcggcg tcgtcaattg accggatacc gcccgctaca
     5281 caaaacggaa tgtcgatcac ctcggcaacg cgcgctaccc agcttttatc gactacgcga
     5341 ccatcgctgg aggcggtaat gtcatagaac accagttcgt ccgcgccttc gtcggcatag
     5401 cgtttggcca gcggaacgat atcgccaatg atctcatggt tgcgaaactg tacgcctttt
     5461 accacctgac catcacgaac gtccagacac ggaattatac gttttgccag cattggatgg
     5521 cctccttaac ggtaaatttc ccttccaaca gcgcgcgtcc gacaatcacg ccgcgcacgc
     5581 cggtgccgcg cagggcggca atatcatcga tatcgccaat accgccggag gattgaaagg
     5641 cgatctgcgg atatctggcg catatctctt cgtacagtga aacgttagag cccgccagcg
     5701 tgccgtcgcg agaaatatcg gtacacagta catgtttcag gccgacgggg agataggtct
     5761 ccaccagttg ttccagcgag acgccggaat tttcctgcca gccgctaacc gccacctgct
     5821 tgttgccgtg ttcgtctatg cgaacgtcca gcgccagtac cagcgcctgc gcgccaaaac
     5881 gttcaaacca gcctttcacc acgtcagggg atttcaccgc cgttgaaccg atgaccacac
     5941 gggcaacgcc agctttcagt aatgccgcaa cgtcttcttc ggtacgcacg ccgccgccga
     6001 cctgaacagg cacgttcacg cccgcgacca gagttttaat cagcggtatc tgtcgcttag
     6061 ccggatcttt agcgccggtc agatctacca gatgtagcac cccggcgccc tgggcggcgt
     6121 aatcctgcaa acggggcagg ggatcgttac cgtaatcccg ctgccgggcg tagtcgccct
     6181 ggtggagacg caccacggtg ccgtcaatta aatctaatgc cggaataatc attacatctc
     6241 caggaagttt ttcagcaact gtgcacccgc cgcgcccgaa cgttccggat ggaactgtac
     6301 gccgaagaaa ttatctttct gtaccgccgc ggtaaacggc tcgccgtaat tgcactgggc
     6361 gatagtccac gggttgaccg gcatcgcgta gctgtgaaca aagtaaaaat aggcgccatc
     6421 ttcaatgccc tgaaacagcc ggttgcccgc ctgcggatac acgcgattcc agcccatgtg
     6481 tggcagcggc agaccaaagt cggtcatttt cggcacatct tgttcgataa tgttcagcag
     6541 atccacgccg cgcgtctctt cgctgcgacg acccagcagt tgcatcccta agcagatacc
     6601 cagtaccggc tgagtacacg ctttaattaa gtcgatcagt tcacgttcgc gcagttgatc
     6661 catagcggct tgcgccgtgc cgacgccggg cagaaagagt ttgtcagcgc gtaatacgat
     6721 ttccgcttcg cggctgacca ccggggtgta accgtggcgc gccacggcgg attttaccga
     6781 gcttaaattg gcgcagccgg tgtcaaggat gacgacgttc atcacagcac tcctttcgag
     6841 gacggtaatg tatcgccctc cacgcgaata gcctggcgta gcgtccgacc aaaggcttta
     6901 aacaaacttt cgacacggtg gtgatcgttc ttacctttag tcttgagatg cagagtgacg
     6961 cccatcgtgt aagagagtga gcggaaaaag tgttcaatca tctctgtgct caaatcgccc
     7021 acacgctggt aggtaaattc agctttatat tccagatgcg gacgaccgga aatatccagc
     7081 gcgcagcgcg ccagacattc atccatcggt agtacaaagc caaaacggca gataccgcgc
     7141 ttgtcgccga gtgccagttt taacgcctca ccgagcgcca gcccggtatc ttctaccgtg
     7201 tggtgatcgt cgatatagag atcgccctta acggtaatct ccatgcgaaa gccgccgtgg
     7261 gtggcgattt gatcgagcat atggtcaaag aagccgacgc cggtattaat cttgctgttg
     7321 ccttcgcgat ccagccagac gctgacatca atctgtgtct ctttggtgtt gcggaccaca
     7381 tgcgcatagc gatcgcgttt cgttagctgt tcgccaatca tcgtccagtt caacgtttca
     7441 cggtgatagc gtaaaccagt aatgcccata ttatcagcga gttggatatc ggttgcacga
     7501 tcgccaatca catagctgtt ggcgctatcc atcgcttgtt ccgcaagata acgctccacc
     7561 agcttcactt tgggcttgcg gcagtcgcag tcgtctgcgg gcaggtgagg gcagatcagc
     7621 acctcatcaa agcatacgcc ctgagaagtg aaaatctgca tcatcaggtt gtgcggtccg
     7681 tcgaagtccg cctgcgggaa gctttgcgtg ccaagtccat cctggttagt gatcatcacc
     7741 agcttaaaac cggctttttg cagcttcagc aatacgggaa tcacctctgg ctcaaaggcc
     7801 agtttatcaa agtggtctac ctgaaaatcg ctcggcggtt cggaaattaa ggttccgtcc
     7861 cggtcgatga aaagatactt ctgactcata ctggctccgc acgtaaggcg tcaatgacgc
     7921 gctggttttc ctggcgggtg ccgaccgtaa tccgcaggca gccgcttaaa gaaggttgtt
     7981 tattctgatc gcgtaagata atgccctgat cccataagga tttaaacacg ctgctggagg
     8041 cggtaaaccg cgccagaata tagttggttt cagagtcaaa gacgtgttct acgcaggcgg
     8101 tctgttgcag ggcattcacc agatactgac gttcctgcac tgtctgcgcc acgcgatcgc
     8161 gcattacgtt tattccctgc gggctcagcg cttgggcggc gatatccgcc actggcgtag
     8221 aaagcggata aggggcgatc acttttaaca gcaggttgat cacctcttca ttagccagcg
     8281 taaagccgca gcgcagaccc gccagcgcaa aagctttcga caatgtgcgc aggataacca
     8341 gatgaggata tttaaccagc cagcctgcca gcgtggcctg cgggcaaaac tcaatataag
     8401 cttcgtcggc gacgactatc gctttaccgc gtgtcaactc cagcagcgtg cgcagatcct
     8461 gcgggttgat aagttgcccg gtaggattat tggggctaca aacgaacacc acttttgcgc
     8521 cgtcaaggtt gtcggaaatc ccctgtagat ccagctgcca gttttcaagc gcgggaaccg
     8581 tccggcgctc tacgccaatg gtttcggcgc tgacgctgta cataccgtaa gtgggcggac
     8641 agtagagaat ggcgtctttc cccggttcgc agaaggcgcg gatcaccagt tcgatccctt
     8701 catccgcgcc gcggctgacc agcacctgct ccggctttac gccagcatat tgcgcgtagt
     8761 tttcaatcac ggcctttggc tggcattccg ggtagcggtt aagcgtttgt tgggtgagct
     8821 gaaactccac cgctgtcggg aattcattcg cgttcagcca gacatcgccg ttaccgccca
     8881 gacggcgggc ggactgatac ggtaccaggt tgcggacatt ttcacgggct aagtctgcga
     8941 cgctgagagt gttttcagtg ctcatgcttg ctccttgagg gcgtttacgc gcagggtcac
     9001 ggcattttta tgggcggtca gacgttctgc cgccgccaat gtttcaatgg ttgatgccag
     9061 agcggaaaag cccgctttcg acagttcctg aacggtcatc cgtttctgga aatccgctaa
     9121 cccaaggctg gaacaggtag cagtatagcc ataggtcggt aaaacatggt tggttccgga
     9181 agcgtaatca ccggcggatt ccggcgacca gtcgccgaga aataccgagc ctgcgctggt
     9241 aatcgcatcc accaaatcgc gcgcattgcg cgtctggata attaagtgtt ccggcccata
     9301 ctgattagag atggcgacgc actgcgctaa atctttggtc acaatcagac gactggcgct
     9361 cagggcctgc cgggcggtgc ccgcgcgcgg cagttccgcc agttgacgtt ctaccgcctc
     9421 cgccaccttg cgggcaatgt cagcatccgg cgtcagcagg atcacctggg aatccgggcc
     9481 gtgctcagcc tgggagagca ggtcagaagc gacgaaatcc ggtgttgcgc cgctgtcggc
     9541 gatcaccagc acttcagacg gcccggctgg catatcgata gccgcgccgt cgagacgctg
     9601 gctgacctga cgcttggctt cggttacaaa ggcgttgccg gggccaaaaa ttttatccac
     9661 tttcggtacg gactcgctgc cgaaggccag agcggcaatc gcctgcgcgc cgccgacgtt
     9721 aaagatttcc tgcacgccac acagttgcgc cgcatagagg atttcatcag cgatgggtgg
     9781 cggcgagcac agaaccacct tctggcatcc cgcaatgcgc gccggcgtcg ccagcatcag
     9841 caccgttgag aagagcggag ccgagccgcc gggaatatac agaccgacag acgcgacggg
     9901 acgcgtaacc tgctggcaac gcacgcctgg ctgggtttcc acatctacag gcggtagcgt
     9961 ctgcgcggaa tggaacgttt caatattttt gacggcagcg gccatcgcct gttttaattc
    10021 gtcgctcaga cgcgcgccgg cggcggcgat ctcttcaggg gtgacgcgta gcgctgtcac
    10081 ttctgtttta tcaaatttag cgctgtattc acgcagggca tcgtcaccgc gcgtttttac
    10141 attatacaga atatcgctga ccgtccgggt aatactgtca aaggcggaaa tcgccggacg
    10201 cgtcagcagc gcacgctgct gttcagggct acagctgttc cagtcaatca gggtattgaa
    10261 gctcatggtc tttactccat cacagggttc cgccttatcc ggcctactga acccaaaata
    10321 tcaacgcatt acgtaggcct gataagcgca gcgccatcag gcgtcagatc actccatcat
    10381 cttctcgatc ggcagtacca gaatcgagct ggcgccaagc gctttcagtt tctccatggt
    10441 ttcccagaac aacgtttcgc tgctgaccat gtgcatcgcc acgcgctgtt gctcgcctgc
    10501 cagcggcaga attgtcggcc tttcggcgcc tggcagcagg gcgataacct cttccagtcg
    10561 ttcacttggc gcgtgcatca tgatgtattt cgattcgcgc gcctgaatca cgccctgaat
    10621 acgggtcagc aatttatcga tcagctgttg cttgctctgt gccatctcac cgtcgcgctg
    10681 aatcagacag gctttagagc ggtagataac ttcgacttca cgcaggccgt tagcttcaag
    10741 cgtcgcgccg gtagagacca aatcgcagat agcgtcggcc agccccgcgc gcggcgcgac
    10801 ttcgacagaa ccatttaaca gacacgattt aaaagagacg cctttctggt cgaggtagcg
    10861 tttgaggagg tgcggataag aggtagcgat acgtttaccg tccagcgcgg ccgggccgtc
    10921 ccaggcttcg tcaaccggcg ttgccagcga taaacggcag ccgccgaagt caagacggcg
    10981 cagggttaaa tagcgtggat cttcgccctg cgcgcggcgg ttgagtagct cttcttccag
    11041 cacgttttcg ccgataatac cgagatcgac cacgccatcc atcaccagac ccggaatgtc
    11101 atcatcacgc acgcgcagga tatcaatcgg catgttttcc gccatcgcaa tcaggcgctg
    11161 agtgtgtaaa ttaattttta tgccgcagcg ggccagcaat tctcgtgaat catcgcttaa
    11221 acggcctgat ttctgaatag ctatgcgtaa gcgggtgttg tctaacattc tgcgttcctc
    11281 tttatcctgt ctgaaccggt ctgtatcgcg cgccaaaaaa aaagcccccg gaagatgatc
    11341 ttccgggggc tttctcatgc gttcatgcac cactggaaga tctgaatgtc ttccagcaca
    11401 catcgcctga aagactagtc aggatgatgg tgatgtttaa attgaacgcg tgtcataaaa
    11461 attccgatga atgcttattc atttgatacc ttttaaccta aaccactttt acgccttaaa
    11521 gcaagcgctt ttttcatttc gcatttatag tatgaattgt cagtcacggc gggctggcgt
    11581 agccttatgt ataaggcgtt aaagtcagga gaaaatggat gaaaaaggtc gcaattgtcg
    11641 gtttaggttg gttaggcatg ccgctggcaa tgtcgctggc agcgagaggc tggcaggtta
    11701 ccggcagcaa aaccaccctt gacggggtgg aagcggcccg tatgagtgga attgaaagct
    11761 atccgctgcg tctggagccg gagctggtct gtgaggcgga cgatcttgac gctctgctgg
    11821 atgtcgatgc gctggtgata acactgcccg cgcgccgtag cggtccggga gaggattttt
    11881 atctgcaggc gatgcaggag ctggtcgaca gtgcgctggc ttatcgtatc ccgcgtatta
    11941 tttttaccag ttcgacgtct gtttacggcg atgcgcaagg cgtggtgaaa gagaatacgc
    12001 cgcgtaatcc ggtcacggcc agcgggcgta ccctgaagga actggaagat tggctgcata
    12061 atctgccggg cacgtcagtg gatattctgc ggctggcggg gttagtcggg cctgggcgcc
    12121 atcccggacg tttctttgcc ggaaaaaccg cgccggatgg tcaacacggg gtcaatctgg
    12181 tgcatcttga agacgtggtt ggcgcaatta cccttttgct acaggcgcca aaaggggggc
    12241 acatctataa tatatgtgcg ccggcgcatc cagcccgcaa cgtgttttat ccgcaaatga
    12301 cgcgcttgct gggaatggcg ccgccgcatt ttcgtgacgc accggacaac ggcaaaggga
    12361 agattatcga cggtagccgg atttgtaatg agctgggatt tgaatatcaa tatcccgatc
    12421 cgttggtgat gccgatggag tgagtcgctg tccagcaggt ggtcgccata tagcgcaagg
    12481 ggacgagtat gaaaccactg ctggacgttc tgattattct tgatgcgtta gaaaaagaag
    12541 gcagcttcgc ggcggcgtcg gcaaaattat ttaaaacgcc gtccgccctc agttataccg
    12601 ttcataagct ggaaaacgat cttaatatcc aactgctcga ccgtagcggg catcgcgcgc
    12661 gatttacgcg aaccggtaag atgctactgg aaaaaggccg tgaagtgttg cacaccgttc
    12721 gcgagctgga aaagcaggcg attaaactgc atgaaggctg ggagaacgaa ctggtcatcg
    12781 gtgtggatga tacctttccc ttttctcttc tggccccgct tatcgacgct ttttatcaac
    12841 gccacagcgt gacgcgcctt aaatttgtca atggcgttct cggcggttca tgggagacgc
    12901 tgacgcaggg aagggcggat attattgttg gcgccatgcg cgcgccgccg cctgacaccg
    12961 gctttggctt tgcaagactg ggcgatcttg aactggtgtt tgctgtcgcc ccgcatcatc
    13021 cgctggttca tgaagaggaa ccgcttagcc gccagacgat caaacgtttt cgcgcgattg
    13081 tggttggcga tagcgtccat tcctcgcgat caatagggtc tgaactgctc gacgctcagg
    13141 aagcgattac cgtgtttgat tttaaaacca agctggagct gcaaattagc ggcctgggat
    13201 gcggctattt accgcgttat ctggcgcagc gatttttgga aagcggcgcg cttatagaga
    13261 agaaagttgt ggcgcaaatc gtctatgaac cggtgtgggt tggctggaat gaacagaccg
    13321 ccgggctggc cagcggctgg tggcgggatg aaattttagc aaataatgct attgctgggg
    13381 tgtatgcaaa atcgccggtt taaaaatcaa tcgcttatga aaaataattt tttgaacgcg
    13441 ctcgcattct cttgtcattt cacttcaatt tagggcagaa tatgccgctt gcaaaaaatg
    13501 acactaaccg acgttttaat acgcgtcggt tatttttttg cttcaaacac atcattcaat
    13561 accaagaggc cgggcttcgt accggataga tacttactta aaaatcgaca gttgttgtcg
    13621 ctgaggaatc cagaaaatgg ggcaattttt tgcttacgcg acggcattcg ccgtaaagga
    13681 gaatgaccat gtcgcataac gttactccaa acacctctcg cgtggaatta cgtaaaacgc
    13741 ttacgttagt tccggttgta atgatgggtc ttgcctatat gcagccgatg acgctgttcg
    13801 atacatttgg tatcgtttca ggcctcactg acggtcacgt accgacggcg tatgcattcg
    13861 cgttaatcgc gattctgttt acggcgttga gctacgggaa actggtgcgt cgctatcctt
    13921 ccgcgggttc ggcgtacacc tatgcccaga aatccatcag cccgaccgtt ggctttatgg
    13981 tgggttggtc ttctctgctc gattatctgt tcgcgccgat gatcaacatt ctgttggcga
    14041 aaatttattt tgaagcgctg gtgccctcca ttccctcatg ggtgttcgtc gtggcgctgg
    14101 tggcctttat gacggccttt aacctgcgca gcctcaaatc ggtcgctaac ttcaacactg
    14161 tgattgtggt gctacaggtg gtgctgattg cggtcattct gggcatggtg gtttatggcg
    14221 tatttgaagg cgaaggcgcc ggtacgctgg cgagcacccg tccgttctgg tccggcgatg
    14281 cgcacgttat cccgatgatt acgggagcga cgatcctgtg cttctccttt accggctttg
    14341 acggcatcag taacctgtcg gaagagacca aagatgctga gcgcgtgatc ccgcgtgcga
    14401 ttttcctgac cgcgctgatt ggcggcctaa tcttcatctt tgcaacctat ttcctgcaat
    14461 tgtacttccc ggatatctct cgctttaaag atccggatgc gtctcagccg gaaatcatgc
    14521 tgtacgtggc gggtaaaacc ttccaggtgg gcgcgctgat cttctctact atcaccgtac
    14581 tggcttccgg tatggcggcg catgcaggcg tagcgcgcct gatgtacgta atggggcgcg
    14641 acggcgtatt cccgaaaagc ttcttcggtt acgttcatcc gaaatggcgt acgccagcga
    14701 tgaacatcat cctggtcggg gcgatcgcgc tgctggcgat taattttgac ctggtgatgg
    14761 cgacggcgct gattaacttt ggcgcgctgg tcgcgtttac cttcgttaac ctgtcggtga
    14821 tttcgcagtt ctggatccgt gagaagcgta ataagacgtt gaaggatcac ttccagtatc
    14881 tgttcctgcc catgtgcggc gcgctcacgg ttggcgcgtt gtgggttaac ctggaagaaa
    14941 gctcaatggt actgggcctg atctgggcgg gtatcgggct gatttatctg gcgtgcgtaa
    15001 ctaaaagctt ccgcaacccg gttccacagt acgaagacgt cgcgtaatcg cgcgtattat
    15061 cggcaatagt aaaaccggag gcagtgcctc cggttttttg tctgccatcc agcacgttta
    15121 ccggatggcg gcgtcactat ttatccgctc tggattaaca atgcccgtca ggcattggtc
    15181 aattacacaa tctcagttgc gtactgccac agtgatttca gcagccccag cttcgtttta
    15241 tcttccgcat actgctgaga aagcatctgc aattcattgg catactgttg taaaaactct
    15301 ggcgtcagta cctgacggcg atgctccagc cagcgctgct gctctgcgtc atccagcgta
    15361 ccgggaaaat tgcgtgcgcg gtaattaaac agcagcttct caatgcgctt atcgacaaag
    15421 gtaatgtcca gcgcgggcag gttacgcggc tcggtttcga gtacgatttt catggctgcg
    15481 cgatcggcat cgctgaaaaa accatcatag agctgggcat caacgttatc cgaggtggca
    15541 aaaggttcgg cttcggcgaa aatcgccacc actttgtcgc ggacctgcgg gttttcacgc
    15601 agcactttca ggttatccag gcaatgctgg cggttaattc ccagccggtc ggcatcctcc
    15661 gggcgcaagg tattcgcctg cgccagtacc ggacatttat tgatatgcac cagctttacc
    15721 ggcactgcgg cgtgatcgcc aagatcggct ttggccgtat aaagccgctc gcgaagggtg
    15781 tcgctgtcca gctcaagaag aggagaaata tcgcctgcta aatcgaccat gatcaccgcg
    15841 ttacggtttt caggatgcca cgccagcggc gcgacccagc ttgtattacc gcgccacgcg
    15901 ccaaacatgc cggagacatg caccagcggc ttcatttgcg gaacgtcaat cagcgccgcc
    15961 agtttatgtt tactgcggtg gctataaaga taatcaaaca gtcgcggctg gcgtgttttc
    16021 accagttgcg ccatcgcaat agtggcgtag acatccgcca tcgcatcatg cgcgttgctg
    16081 tgttcgatcc cgttcgcctg ggttaaatgt tccagacgaa agctgggcag gccgtcgtcg
    16141 ttttccggcc agttaattcc ctccgggcgc agcgcataac aggcgcgcat gacatccaat
    16201 agatcccaac gtgaattatc atgctgccag ctccaggcgt agggatcgta aaagttgcga
    16261 taaaaaatat tgcgcgtgac ttcatcatca aaacgtacat tgttgtagcc cacaacgcag
    16321 gttttaggaa cggtaaacag cgcatgaatg cgtctggcga aagcggcttc gttttctcct
    16381 ttctcacgcg cttcctgcgg cgtgatgccg gtaatcagca ctgcgccggg ctgcggtaga
    16441 taatcatcgg cgggtttgca ataaaacacc tccggctcgc caataacgtt gaagtcgtta
    16501 tccgtacgga gcgcggcgaa ttgcgcaggt ctgtcgaggg ccggatgcgt accgaaggtt
    16561 tcgtaatcgt ggaagaggaa tgtgctctgt atgctgtcgt ttttaactgt cacttgatgt
    16621 acacgcctga tgttatctgt atatgaaata ttttattctt ttattttgtc gttgattgat
    16681 tgtatttgta caccaattga tattgttgct aatgttcgta catgcgatgg tgagtacata
    16741 aacattaaaa tcattgagta caaaatacta aaatgaccat cagcgacact aagctacgct
    16801 ccctctatgg taaaccatat tccggcccat ctgaaattac tgattttgat ttagtactgt
    16861 atggaattta ggccagggtc aatctggccg ggatctcaaa aaatgcatgg actaaaacgg
    16921 gtctatgtac agagggacac aacgctgtgt cccttaattt catgcgggtt gaggctggac
    16981 taggcccagg ccagtggcag gatggatgac agaacactcg ggaaatattt tctggcatga
    17041 cgttgcatac tatccaccac aacgctggta caggtaaagg cgccatggag gccgtgaaaa
    17101 cggtcggacc agtcggtaaa ctgttcgctg gacgggaaga tcgccggaga cagctcccag
    17161 tctttctgca tcagcgcctc cgcatagcct ctcagggccg gcggagagtc atgctcagtg
    17221 ccgaaaatgg cgctggagga atagcgtgcg aatgcggtac taagacagaa cagggtttcc
    17281 gcctgcttct gtggggtggc gtccgtcagg tgataagcac tgaggatgtg ctggtagtgt
    17341 gccgggctga gtttgccttc aggaagcagg gggtcaaaaa tggtgttcag acgcgacact
    17401 gaggcatcat caatcaactt cacggtggaa tgtttctggg tcgtggcggc aataaactgc
    17461 tggttcagct ccccgtgctc ttcagcgctg aggatgatat caatcagttc cccaaagcgt
    17521 cgctgcacgg cctgctgatt aaatgcggcg agaaacaccg gaaagtcatg acggaataac
    17581 tctaccggag agatttgcgc ggtggaaacg ttctctccgg ctcgcagcag gtaaaagttg
    17641 tcccatgcag tgtcaggagt agggtttagc attgttaaca gcgtgtcagt ggagagcatc
    17701 atcgccgtgt ctgaatcctg ggaggaaagc agcaggaaat tatctgcagc gcgggttgtc
    17761 cagtccgggc tgccgtcata attgccgaag agcccattat ggatgtgggg agacaccgtt
    17821 gggtgagcaa gatatcgttc ataaagcgct gcagctttct ggcgggtgcc atcagtgcag
    17881 cccacgcctg tcatacagtg taaaatcacc tgattaaaga gtccgttgtg agtggtcatg
    17941 gcggcgttgt tcctgtcaaa cgaatccagc aacacaggcc gtatgcgctg ctgataatat
    18001 gtgtcaggag ccggcagggg aacgtcatta taggtctggc actggtgggc aaaaaaacgt
    18061 tcctgaacag gcccgagcca ctcgctgata agcgtacttt gcgtataggg ggggccagta
    18121 cgctcaccag cgaactttca actggccgga tacatgcctc tgttaagcgg ccactccgca
    18181 atgacttaac caggtcttcc attgcccgga ctttttcctg actgtattta tcgggcaggc
    18241 tgtcaatggt tatcagaata cttttaccat tattgtgctc atgatttaaa aatccatcca
    18301 cagcgttctc agtccaaagg agtggcattt gcggccagat atcacctgga cgaataaaat
    18361 tttcgccccc tgatactgac ggaggtgatg aattatccgg ttcatttaaa ataacgccag
    18421 agaggttggc tttgtgacgt ataagcgtat tttttaatgt tgtatcaata aaagagggct
    18481 gttgttgtgt agtaattgaa tactgtaaaa cacttcattc atgtctgaat tactaaattt
    18541 tgtattactg cagactacat cactcagtgt caaataagtg aatcggcatt cgtcaaaatg
    18601 taaatgagat atatcagaat aagtaaattt tgaatttgaa aagttgaacc tcttaataat
    18661 atcgccgtct cgctccatga agc
//
LOCUS       DAJVBX010000076        18653 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.076, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000076 DAJVBX010000000
VERSION     DAJVBX010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 18653)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18653)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18653
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.076"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(172..549)
                     /locus_tag="OPV72_002291"
     CDS             complement(172..549)
                     /locus_tag="OPV72_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001535855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HCR9914572.1"
                     /translation="MHKYLSVVKKHRVPLSDAAVDLLKDLPRLKDNNHVFPAPRAETL
                     SDMSLLAVLKRMGYIDLTQHGFRSTFREWAGEATDYQREVIEHALAHQLADKAEAAYQ
                     RGTLWPKRVALMDDWTGYSTANS"
     gene            complement(908..995)
                     /locus_tag="OPV72_002292"
     tRNA            complement(908..995)
                     /locus_tag="OPV72_002292"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(959..961),aa:Ser,seq:gga)
     gene            complement(1144..1821)
                     /locus_tag="OPV72_002293"
     CDS             complement(1144..1821)
                     /locus_tag="OPV72_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HCR9914573.1"
                     /translation="MSSPASFNGLRPVIDVNDSVMLLIDHQSGLFQTVGDMPMPELRA
                     RAAALAKMATLAKMPVITTASVPQGPNGPLIPEIHANAPHAQYIARKGEINAWDNEDF
                     VKAVKATGRKTLIIAGTITSVCMAFPAISAVAEGYKVFAVIDASGTYSKMAQEITLAR
                     IVQAGVVPMDTAAVASELQGTWNREDAAAWADVYTQVFPAYQLLIESYSKAQDVVKNN
                     EMLDSQR"
     gene            complement(1841..2701)
                     /locus_tag="OPV72_002294"
     CDS             complement(1841..2701)
                     /locus_tag="OPV72_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pirin family protein"
                     /protein_id="HCR9914574.1"
                     /translation="MKQITGVYTAPRPHWVGDGFPVRSLFSYQSHAQQLNPFLLLDYA
                     GPHTFTPGNEKRGVGEHPHRGFETVTIVYSGEVEHRDSTGRGGVIGPGDVQWMSAGAG
                     ILHEEFHSDAFTRRGGELEMMQLWVNLPMKDKMTTPGYQSITHDVIPTVTLPDDAGVV
                     RVIAGRYEETKGPAHTFSPLNVWDMRLQRNRQLTLAQPEGWSAALVVLKGNITVNGTT
                     PANEAQLVVLSQQGKTLHLEASSDASVLLLSGEPLNEPIVGYGPFVMNTKQEIAEAVR
                     DFNSGRFGQI"
     gene            2810..3721
                     /locus_tag="OPV72_002295"
     CDS             2810..3721
                     /locus_tag="OPV72_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCR9914575.1"
                     /translation="MIKTDLNDFAWFVHVVEEGGFAAAGRALDEPKSKLSRRIAQLEE
                     RLGVRLIQRTTRQFNVTEVGQTFYEHCKAMLVEAQAAQDAIAALQVEPRGIVKLTCPV
                     TLLHVHIGPMLAKFMARYPDVSLQLEATNRRVDVVGEGVDVAIRVRPRPFEDSDLVMR
                     VLADRGHRLFASPDLIARMGIPSAPAELSHWPGLSLASGKHIHRWELYGPQGARAEVH
                     FTPRMITTDMLALREAAMAGVGLVQLPVLMVKEQLAAGELVAVLEEWEPRREVIHAVF
                     PSRRGLLPSVRALVDFLTEEYARMVEE"
     gene            complement(3812..4030)
                     /gene="infA"
                     /locus_tag="OPV72_002296"
     CDS             complement(3812..4030)
                     /gene="infA"
                     /locus_tag="OPV72_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HCR9914576.1"
                     /translation="MAKEDNIEMQGTVLETLPNTMFRVELENGHVVTAHISGKMRKNY
                     IRILTGDKVTVELTPYDLSKGRIVFRSR"
     gene            complement(3958..4341)
                     /locus_tag="OPV72_002297"
     CDS             complement(3958..4341)
                     /locus_tag="OPV72_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914577.1"
                     /translation="MFSAHFLLGCYNCCRRIGLAHYHAARCQVTPIVYFTVPLYVALM
                     SIHQAVVSGKRCITRRCRVSRNHVLNLVCCVLNAQIFTYQKKFGIILPVQIMVVIPQR
                     IRWPKKTILKCKVPFSKRYLIPCSA"
     gene            complement(4342..5046)
                     /gene="aat"
                     /locus_tag="OPV72_002298"
     CDS             complement(4342..5046)
                     /gene="aat"
                     /locus_tag="OPV72_002298"
                     /EC_number="2.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl/phenylalanyl-tRNA--protein transferase"
                     /protein_id="HCR9914578.1"
                     /translation="MRLVQLSRHSIAFPSPEGALREPNGLLALGGDLSPARLLMAYQH
                     GIFPWFSPGDPILWWSPDPRAVLWPEKFHLSRSMKRFHNASPYRVTLNYAFDRVIDGC
                     ANHRDEGTWITRGIEEAYRRLHELGHAHSIEVWRDRELVGGMYGVSQGALFCGESMFS
                     RQENASKTALLVFCAEFTRHGGKLIDCQVLNSHTASLGAIEIPRRDYLDHLAALRQQP
                     LASRFWVPRTLFLPRK"
     gene            complement(5091..6812)
                     /gene="cydC"
                     /locus_tag="OPV72_002299"
     CDS             complement(5091..6812)
                     /gene="cydC"
                     /locus_tag="OPV72_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine/glutathione ABC transporter ATP-binding
                     protein/permease CydC"
                     /protein_id="HCR9914579.1"
                     /translation="MRALLPYLTLYKRHKWMLTLGIALAILTLLASIGLLTLSGWFLS
                     ASAIAGFAGIYSFNYMLPAAGVRGAAITRTAGRYFERLVSHDATFRVLQHLRIYTFSK
                     LLPLSPAGLARYQQGELLNRIVADVDTLDHLYLRVISPLVGAFVVIMIVTLGLSVLDV
                     TLAITLGGIMLLTLFIMPPVFYRAGKNTSQNLTHLRGQYRQQLTSWLQGQAELTIFGA
                     SKRYRAQMEATELQWHEAQRRQSELTALSQALMLLIGALAVMLMLWMASGGVGGNMQP
                     GALIALFVFCALAAFEALAPVTGAFQHLGQVIASALRITELTEQKPEVTFPQAETPAP
                     EKVTLTLRDVSFRYPDQPINALNALSLQANPGEHVAILGRTGCGKSTLLQLLTRAWDP
                     QQGEILLNDLPLSSLSESALRRTISVVPQRVHLFSATLRDNLLLAAPNASDEALSDML
                     RRVGLENLLEDSGLNSWLGEGGRLLSGGELRRLAIARALLHDAPLMLLDEPTEGLDAT
                     TESEMLELLADVMREKTVLIVTHRLRGLARFDQIIVMDDGRIIERGTHAELLAGQGRY
                     YQFKQRL"
     gene            complement(6813..8579)
                     /gene="cydD"
                     /locus_tag="OPV72_002300"
     CDS             complement(6813..8579)
                     /gene="cydD"
                     /locus_tag="OPV72_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine/glutathione ABC transporter
                     permease/ATP-binding protein CydD"
                     /protein_id="HCR9914580.1"
                     /translation="MNKTRQKELTRWLKQQSVISQRWLNISRLLGFMSGVLIVAQAWI
                     MARILQHMIMENIPREALLLPFILLILIFVLRAWVVWLRERVGFHAGQHIRFEIRRQV
                     LDRLQQAGPAWIQGKPAGSWATLVLEQIDDMHDYYARYLPQMALAVCVPLLIVAAIFP
                     SNWAAALILLGTAPLIPLFMAMVGMGAADANRRNFLALARLSGHFLDRLRGMETLRIF
                     GRGEAETESIRAASQDFRQRTMEVLRLAFLSSGVLEFFTSLSIALVAVYFGFSYLGEL
                     NFGHYGTGVTLAAGFLALILAPEFFQPLRDLGTFYHAKAQAVGAADSLKTFLETPLAH
                     PARGEVELAENEPVTIDAVNLIITSPEGKTLAGPLNFSLAAGERAVLVGRSGSGKSSL
                     LNVLSGFLSYQGSLRINGVELRDLSPESWRQHLSWVGQNPQLPAATLRENVLLARPDA
                     SEQELYAALDAAWVSEFLPLLPQGVDTPLGNHASRLSVGQAQRVAVARALLNPSQLLL
                     LDEPAASLDAHSEQRVMQALKAASKRQTTLMVTHQLEDLADWDAIWVMQDGAIVEQGS
                     YAELSAANGAFATLLAHRQEDI"
     gene            complement(8693..9661)
                     /gene="trxB"
                     /locus_tag="OPV72_002301"
     CDS             complement(8693..9661)
                     /gene="trxB"
                     /locus_tag="OPV72_002301"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HCR9914581.1"
                     /translation="MGTTKHSKLLILGSGPAGYTAAVYAARANLQPVLITGMEKGGQL
                     TTTTEVENWPGDPNDLTGPLLMERMHEHAAKFETEIIFDHINNVDLQNRPFRLTGDSA
                     EYTCDALIIATGASARYLGLPSEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVE
                     EALYLSNIASEVHLIHRRDGFRAEKILIKRLMDKVENGNIILHTNRTLEEVTGDQMGV
                     TGLRLRDTQQSDNIETLDIAGLFVAIGHSPNTALFEGQLELENGYIKVQSGTHGNATQ
                     TSIPGVFAAGDVMDHIYRQAITSAGTGCMAALDAERYLDGLADASK"
     gene            10208..10702
                     /gene="lrp"
                     /locus_tag="OPV72_002302"
     CDS             10208..10702
                     /gene="lrp"
                     /locus_tag="OPV72_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001591745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-responsive transcriptional regulator
                     Lrp"
                     /protein_id="HCR9914582.1"
                     /translation="MVDSKKRPGKDLDRIDRNILNELQKDGRISNVELSKRVGLSPTP
                     CLERVRRLERQGFIQGYTALLNPHYLDASLLVFVEITLNRGAPDVFEQFNAAVKKLEE
                     IQECHLVSGDFDYLLKTRVPDMSAYRKLLGETLLRLPGVNDTRTYVVMEEVKQSNRLV
                     IKTR"
     gene            10837..14868
                     /gene="ftsK"
                     /locus_tag="OPV72_002303"
     CDS             10837..14868
                     /gene="ftsK"
                     /locus_tag="OPV72_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HCR9914583.1"
                     /translation="MSQEYTEDKDVTLTKLSSGRRLLEALLILIALFAVWLMAALLSF
                     NPSDPSWSQTAWHEPIHNLGGAPGAWLADTLFFIFGVMAYTIPVIIVGGCWFAWRHQS
                     TDDYIDYFAVSLRLIGVLALILTSCGLAAINADDIWYFASGGVIGSLLSTTLQPLLHS
                     SGGTIMLLCIWAAGLTLFTGWSWVSIAEKLGGWLLNILTFASNRTRRDDTWVDDEEYD
                     DEYDEETDGVQRESRRARILRGALARRKRLAEKFSNPRGRQTDAALFSGKRMDDDEDI
                     QYSARGVAADPDDVLFSGNRATQSEYDEYDPLLNGHSVTEPVAAAAAATAVTQTWAAS
                     ADPIMQTPPMPGAEPVVAQPTVEWQPVPGPQTGEPVIAPAPEGYQPHPQYAQPQEAQS
                     APWQQPVPVASAPQYAATPATAAEYDSLAPQETQPQWQAPDAEQHWQPEPIAAEPSHM
                     PPPVIEQPVATEPEPGIEETRPARPPLYYFEEVEEKRAREREQLAAWYQPIPEPVKEN
                     VPVKPTVSVAPSIPPVEAVAAAASLDTGIKSGALAAGAAAAAPAFSLATGGAPRPQVK
                     EGIGPQLPRPNRVRVPTRRELASYGIKLPSQRIAEEKAREAERNQYETGAQLTDEEID
                     AMHQDELARQFAQSQQHRYGETYQHDTQQAEDDDTAAEAELARQFAASQQQRYSGEQP
                     AGAQPFSLDDLDFSPMKVLVDEGPHEPLFTPGVMPESTPVQQPVAPQPQYQQPVAPQP
                     QYQQPQQPVASQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQ
                     QPVAPQPQYQQPQQPVAPQPQYQQPQQPTAPQDSLIHPLLMRNGDSRPLQRPTTPLPS
                     LDLLTPPPSEVEPVDTFALEQMARLVEARLADFRIKADVVNYSPGPVITRFELNLAPG
                     VKAARISNLSRDLARSLSTVAVRVVEVIPGKPYVGLELPNKKRQTVYLREVLDNAKFR
                     ENPSPLTVVLGKDIAGDPVVADLAKMPHLLVAGTTGSGKSVGVNAMILSMLYKAQPED
                     VRFIMIDPKMLELSVYEGIPHLLTEVVTDMKDAANALRWSVNEMERRYKLMSALGVRN
                     LAGYNEKIAEAARMGRPIPDPYWKPGDSMDVQHPVLEKLPYIVVLVDEFADLMMTVGK
                     KVEELIARLAQKARAAGIHLVLATQRPSVDVITGLIKANIPTRIAFTVSSKIDSRTIL
                     DQGGAESLLGMGDMLYSGPNSTMPVRVHGAFVRDQEVHAVVQDWKARGRPQYVDGITS
                     DSESEGGGGGFDGGEELDALFDQAVNFVTQKRKASISGVQRQFRIGYNRAARIIEQME
                     AQGIVSAQGHNGNREVLAPPPFE"
     gene            15013..15624
                     /gene="lolA"
                     /locus_tag="OPV72_002304"
     CDS             15013..15624
                     /gene="lolA"
                     /locus_tag="OPV72_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010354356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipoprotein chaperone LolA"
                     /protein_id="HCR9914584.1"
                     /translation="MKKMAIACALLSSVVASSVWADAASSLKSRLDKVSSFHATFTQK
                     VTDGSGAAVQEGQGDLWVKRPNLFNWHMTQPDESILVSDGKTLWFYNPFVEQATATWL
                     KDATGNTPFMLIARNQASDWQQYNIKQDGDNFVLTPKASNGNLKQFTINVGRDGTIHQ
                     FSAVEQDDQRSAYQLKSQQNGAVEPSKFTFTPPQGVTIDDQRK"
     gene            15634..16977
                     /gene="rarA"
                     /locus_tag="OPV72_002305"
                     /gene_synonym="mgsA"
     CDS             15634..16977
                     /gene="rarA"
                     /locus_tag="OPV72_002305"
                     /gene_synonym="mgsA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein
                     RarA"
                     /protein_id="HCR9914585.1"
                     /translation="MSNLSLDFSDNTFQPLAARMRPENLAQYIGQQHLLAAGKPLPRA
                     IEAGHLHSMILWGPPGTGKTTLAEVIARYASADVERISAVTSGVKEIREAIERARQNR
                     NAGRRTILFVDEVHRFNKSQQDAFLPHIEDGTITFIGATTENPSFELNSALLSRARVY
                     LLKSLTTDDIEQVLDQAMQDKTRGYGDQDIVLPDETRRAIAELVNGDARRALNTLEMM
                     ADMAEADDSGKRVLLPALLTEIAGERSARFDNKGDRFYDLISALHKSVRGSAPDAALY
                     WYARIITAGGDPLYVARRCLAIASEDVGNADPRAMQVAIAAWDCFTRVGPAEGERAIA
                     QAIVYLACAPKSNAVYTAFKAALADARERPDYDVPVHLRNAPTKLMKEMGYGQEYRYA
                     HDEPNAYAAGEVYFPPEIAQTRYYHPTNRGLEGKIGEKLAWLAEQDQNSPTKRYR"
     gene            17236..18528
                     /gene="serS"
                     /locus_tag="OPV72_002306"
     CDS             17236..18528
                     /gene="serS"
                     /locus_tag="OPV72_002306"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HCR9914586.1"
                     /translation="MLDPNLLRNEPDAVAEKLARRGFKLDVDKLRALEERRKVLQVNT
                     ENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGEELDAAKAELDTLLAEIRDIALT
                     IPNLPADEVPVGKDENDNVEVSRWGTPREFDFEIRDHVTLGEMHSGLDFAAAVKLTGS
                     RFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNHDTLYGTGQLPKFAGDLF
                     HTRPLEEEADSSNYALIPTAEVPLTNLVRDEIIDEDQLPIKMTAHTPCFRSEAGSYGR
                     DTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLGLPYRKIILCTGDMG
                     FGACKTYDLEVWVPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSG
                     LAVGRTLVAVMENYQQADGRIEVPEVLRPYMNGLEYIG"
BASE COUNT         4365 a         4934 c         5216 g         4138 t
ORIGIN      
        1 gtccgggcat aacctctcct tgagtggttt atgtaatttg caaaccatga taataatcat
       61 ataagaaata gttcatcgtg aaattattac ttatcacatt ttcgaaagcg aatgctatta
      121 gcatcacact ttctacgttg ttatcaacga taatgctttc gtacaggtag cttagctgtt
      181 ggcagtgcta taccccgtcc agtcatccat cagcgccact cgtttaggcc ataacgtccc
      241 acgctgatac gctgcttcag ccttatctgc caactggtgc gccaacgcat gttcaataac
      301 ctcacgttga taatccgttg cttcaccagc ccactcacgg aaagtagaac ggaagccatg
      361 ttgcgttaag tcgatatatc ccattcgttt caatacagcc aataacgaca tatcagaaag
      421 tgtttcagcg cgaggggcag ggaatacatg attgttatct tttaatcgtg gtaaatcttt
      481 taacaaatca acagcagcat cagacagagg aactcggtgc ttttttacta ccgagagata
      541 cttatgcaaa cttttctaaa gcgtttcagg tagggaagta gggctgtttt acacaatcta
      601 tagtaagttt ggtgtagcaa ccaaaggtcc aaaaacaaac ctttcatcag gaaaatcaca
      661 gtaaaaacaa gaagtttaga tacaaaagcc cgtactttcg tacgagctct ttcttgaata
      721 tggcggtgag ggggggattg actcgctttg ctcgcccctt cggggcagcc cgttcgctgc
      781 gcgcccggtc tgtccaactg gctgcgccag ttgtcgaacc ccggtcggtg gttctcatcc
      841 ccccttggtt tgggggatac atataagcaa aaagcccgta cttctgtaca ggctctcaac
      901 ttaaatatgg cggtgagggg gggattcgaa cccccgatac gttgccgtat acacactttc
      961 caggcgtgct ccttcagcca ctcggacacc tcaccatatt gtattgctgc ctgaccgctt
     1021 ggggggcaac ggggcgctac tatagggagt tgcgctaaaa cggtcaagca gaatttacat
     1081 attcactgtc gtttgctcat gcaatagaca taatccccgc ccaaactggc gcggggaggc
     1141 aaattagcgc tgtgaatcca acatttcgtt gtttttcacc acatcctgcg ctttgctgta
     1201 gctttctatc agcagttgat aggccgggaa tacctgagta taaacgtcgg cccacgcggc
     1261 tgcgtcttca cggttccagg tgccttgcag ctcagaggca actgcggcag tatccatcgg
     1321 tacgacgcca gcctgtacga tacgcgccag ggtgatctcc tgcgccatct tactgtaggt
     1381 accggatgcg tcgatcacgg caaatacctt ataaccttct gctaccgcgc taatggccgg
     1441 gaatgccatg cacacgctgg taatcgtccc ggcaatgatc agcgtcttac gacccgtcgc
     1501 ttttaccgcc ttaacgaaat cttcgttatc ccaggcgtta atttcacctt tgcgcgcaat
     1561 gtactgtgca tgtggcgcat tagcgtggat ctccgggatc agcgggccgt tcggaccttg
     1621 cggtacggat gccgtggtaa tgaccggcat tttcgctaac gtcgccatct tcgccaacgc
     1681 cgcggcgcga gcgcgtaatt ccggcattgg catatcgcct acggtctgga aaagaccgct
     1741 ttgatgatcg attaaaagca tcacggaatc gttaacatca attaccgggc gcaaaccatt
     1801 aaaactagca ggacttgaca tcgtgttctc cttcatgttt tcagatttgg ccaaaacggc
     1861 cggagttgaa atcgcggact gcttctgcga tctcttgttt cgtgttcata acaaatgggc
     1921 cgtaacccac aatcggttca ttcagcggct cgcctgataa cagcaatacg ctggcgtcgc
     1981 tgctggcctc aaggtgcagc gttttccctt gctggctcaa taccaccagt tgcgcttcgt
     2041 tggccggcgt cgtgccgttc accgtgatat tgcctttcag taccaccagc gcggcgctcc
     2101 atccttccgg ctgtgccaat gtaagctggc gattgcgttg caggcgcata tcccagacat
     2161 tgagcggcga gaaagtgtgc gccgggcctt ttgtctcttc ataacgccct gcgatgaccc
     2221 gcacgactcc ggcgtcatcc ggcaacgtaa cggtcgggat aacatcgtgg gtaatgcttt
     2281 gataacccgg ggtggtcatt ttgtccttca tgggaaggtt aacccacaac tgcatcattt
     2341 ccagttcgcc gccccgacgg gtaaacgcgt cggagtggaa ctcttcatgc aaaatgcctg
     2401 cgcctgcgct catccactga acgtcgcccg ggccgataac gccgccgcga ccggtagagt
     2461 cccgatgctc gacttcgcca ctataaacaa tcgtcacggt ctcgaaaccg cggtgtggat
     2521 gctccccaac gccgcgtttt tcattacccg gcgtaaaggt gtgcggcccg gcataatcca
     2581 gcagcaggaa tggattcaac tgctgcgcat gtgactgata agaaaagagt gaacgaaccg
     2641 gaaatccatc gccaacccag tgcgggcgag gtgcggtata gacgcctgta atctgtttca
     2701 tggtgttctc ctcagtggcg ttgtcttgat gtgaataagc ttatattcat gacaaaatgt
     2761 tcggtagtgg gtaaaatggc tcataccgtt ccattaatag gacaatgtaa tgataaaaac
     2821 ggatctcaat gattttgcgt ggtttgtgca tgtggtcgaa gagggtgggt ttgccgcggc
     2881 ggggcgtgcg cttgatgaac caaaatcaaa actgagccgg cgtattgcgc aactggagga
     2941 acggctgggc gtgcgattga ttcagcgaac cacccggcag tttaacgtta ccgaagtggg
     3001 gcaaacattc tatgagcact gtaaagcgat gctggtggaa gctcaggcgg cgcaggatgc
     3061 cattgccgca ttgcaggtag agcctcgcgg tatcgtgaag ctaacctgcc cggtgacgct
     3121 gctgcatgta cacatcggcc caatgctggc gaagtttatg gcgcgttatc ctgatgtttc
     3181 gctacagctt gaagcgacca atcgtcgggt ggacgtcgta ggggaggggg tggatgtggc
     3241 gattcgcgtc aggccgcgcc cgtttgaaga tagcgacctg gtgatgcgcg tcctggctga
     3301 cagagggcat cgcctgtttg ccagcccgga tctcatcgca cggatgggaa tcccttccgc
     3361 gccggcggag ttgagccatt ggccagggct aagtcttgca tccggcaagc atatccaccg
     3421 ctgggaactt tacggcccgc agggcgcgcg tgcggaagtc cattttaccc cgcgtatgat
     3481 tactacagac atgttggcgc tacgcgaggc ggcgatggcg ggcgtggggc ttgtgcagtt
     3541 acctgtctta atggtgaaag aacaactggc cgccggtgaa ctggtcgcgg tgctggaaga
     3601 gtgggagccc cggcgggagg ttattcatgc tgtgttccca tcccggcgag ggctattacc
     3661 ttccgtacgt gcgttggtcg attttttgac ggaagagtat gcgcggatgg tggaagagta
     3721 acctgctcgt cattcatcga cttaatggac gcaaaaaagg ccggttaaac cgacctttta
     3781 tccagccgcc cttcagggcg tgaggagaca attagcgact acggaagaca atgcggcctt
     3841 tgctcaggtc gtacggggtc agctcaacgg tcactttgtc gcccgtcagg atgcggatgt
     3901 agttcttacg cattttaccg gagatgtgtg cagtaaccac gtgaccgttt tctaactcta
     3961 cgcggaacat ggtattaggt aacgtttcga gaacggtacc ttgcatttca atattgtctt
     4021 ctttggccat ctaatcctct ggggtatcac taccataatt tgaaccggca agataatgcc
     4081 gaacttcttt tgataagtaa agatttgtgc gtttaaaaca cagcaaacca ggtttagcac
     4141 atgattccgc gacacacgac aacgccgcgt tatacacctt ttccctgata ctaccgcctg
     4201 atgtatcgac ataagcgcaa catataaggg aacggtgaaa taaacgatgg gcgttacctg
     4261 acaacgggct gcgtgataat gagctaaacc aattctgcgg cagcaattat aacaccccaa
     4321 taaaaaatgt gccgaaaaca ttcacttccg gggcaaaaat aatgtccgcg gcacccaaaa
     4381 acgggaggcc agcggctgtt ggcgtaaggc cgcgaggtga tcgaggtagt cacgacgtgg
     4441 aatttcaatg gcaccgagcg aggcggtatg actattaagt acctgacaat caataagttt
     4501 accgccgtgg cgggtaaatt cagcgcaaaa aaccagcagt gcggttttag aggcattctc
     4561 ctggcggcta aacatcgatt cgccgcaaaa tagcgccccc tgcgagacgc catacatccc
     4621 gccgaccagt tcccgatcgc gccacacttc aatggagtgc gcgtggccca attcatgtaa
     4681 tcggcgatag gcttcctcaa taccacgcgt tatccaggtg ccttcgtcac ggtgattggc
     4741 gcatccatca atgacccggt cgaaagcgta attgagcgtc acgcggtaag gggatgcgtt
     4801 gtgaaagcgc ttcatgctgc gactgaggtg aaacttttca ggccacagca cggcgcgcgg
     4861 atcgggcgac caccacagaa tcgggtcgcc cggcgaaaac cacgggaaaa tcccgtgctg
     4921 gtaggccatt aacaaccggg cagggctgag atcgccgccc agtgccagta aaccgttagg
     4981 ctcgcgtaaa gcgccttccg gcgaagggaa ggcgatagaa tgtcgggaaa gctgaaccag
     5041 acgcatgacg gcgaaactcc agtacgcaag tcggatcgtt caataatagc ttacagacgt
     5101 tgtttaaact gataatagcg cccttgtccg gctaacaatt ctgcatgagt gcctcgctca
     5161 atgatgcgcc cgtcgtccat tacgatgatt tgatcaaaac gggccaggcc gcgcaaacgg
     5221 tgagtcacta tcaggacggt tttttcgcgc atcacatcgg caagtaattc cagcatttcg
     5281 ctctcggtgg tcgcatccag cccctcagta ggctcatcca acagcatcaa cggggcatcg
     5341 tgcaacagcg cgcgggcgat ggccaggcga cgaagttcgc cgccggatag cagacgaccg
     5401 ccttcgccga gccagctatt aagcccacta tcttcgagca gattttcgag gccgacgcga
     5461 cgcagcatgt cggaaagggc ttcgtcgctg gcattgggcg ccgccagtaa taaattatca
     5521 cgcagcgtgg cgctgaacag gtggacacgc tgcggcacca cgctgatagt ccggcgtaag
     5581 gcggattcgc tcagcgagga tagcggaaga tcgttgagca gaatttcgcc ttgttgcggg
     5641 tcccaggcgc gggtgagtag ctgcaacagc gttgattttc cgcagccggt acgccccaga
     5701 atagcgacat gctcgccagg attagcctgt aatgagaggg cattgagcgc attaatcggc
     5761 tggtcgggat aacgaaacga aacgtcccgc agggtgagtg tgaccttttc cggcgcggga
     5821 gtttctgcct gtggaaaggt cacctccggt ttttgctccg ttaattcagt gatacgaagc
     5881 gcagaggcga taacctgccc cagatgttgg aatgcgccgg taacgggcgc aagcgcctcg
     5941 aaagccgcca gcgcgcagaa gacaaacagc gcgatgagcg cgccgggctg catattgccg
     6001 ccaacgccgc cggaggccat ccacaacatt aacatcaccg ccagcgcgcc aatcagcagc
     6061 attaacgcct gcgataaggc ggtgagttca gactgtcggc gttgggcctc atgccattgt
     6121 aattcggtgg cttccatttg cgcccgatag cgtttgctgg cgccaaaaat ggtgagttcc
     6181 gcctggccct gtaaccatga cgtgagctgc tggcgatact gaccgcgtag atgcgtcaga
     6241 ttttggctgg tatttttgcc ggcgcgataa aacaccggcg gcataataaa cagcgtcaac
     6301 agcataatgc cgcccagcgt gatcgccagc gtcacgtcga gaacgctaag ccccagggtg
     6361 acaatcataa tcactacaaa agcaccgacc agcggggaga tgacgcgcaa atagagatga
     6421 tccagcgtgt cgacgtcggc aacgatgcgg ttcagcagtt caccttgctg atatcgcgcc
     6481 agacccgcgg gggagagcgg tagaagtttg ctgaaggtat aaatacgcag atgttgcagc
     6541 acgcggaacg tggcgtcatg acttaccaga cgttcaaaat aacgaccagc ggtacgggta
     6601 atggccgcgc cgcgcacgcc ggccgccggg agcatatagt taaaactgta aattcccgcg
     6661 aagcctgcga tagcggacgc ggacaggaac cagccggaaa gcgtcagcag cccgatactg
     6721 gcaagcaggg tcaggattgc cagcgcaatt cccagcgtta gcatccattt gtggcgttta
     6781 taaagcgtca gataagggag tagcgcgcgc atttaaatat cctcctgacg gtgagccaat
     6841 aacgtcgcaa aagcgccgtt ggcggcgctg agttcggcat agctgccttg ttcgacaatc
     6901 gcgccatctt gcataaccca gatagcgtcc cagtcggcga gatcttccaa ctgatgcgtc
     6961 accattaatg tggtctggcg ttttgacgcc gcttttaatg cctgcatgac gcgttgctcg
     7021 ctgtgagcgt ccaggcttgc cgccggttca tccagcagta gcagttgaga gggattaagt
     7081 agcgcgcggg cgaccgctac acgctgtgcc tggccgacgg aaagtctgct ggcatgattg
     7141 ccgagcgggg tgtctactcc ctgcggcagc agcggtaaaa attcgcttac ccatgcggcg
     7201 tcaagcgcgg cataaagttc ctgctcgctg gcgtccgggc gcgccagtaa tacattttcg
     7261 cgtagcgtcg ccgcaggtaa ttgcgggttt tgtccgaccc aggagagatg ctggcgccag
     7321 gattccggcg agagatcgcg aagttcgaca ccattaatac gcaaagatcc ctgataggag
     7381 agaaaaccgg ataatacatt caacagagag cttttaccgg aaccgctgcg tcctaccagg
     7441 acggcgcgtt ctcctgccgc taatgagaaa ttcagcggcc cggcaagcgt tttgccttct
     7501 ggcgaggtga taataagatt gactgcgtca atggttacag gttcgttttc cgccagctca
     7561 acttcgccgc gcgccgggtg ggcaaggggt gtttccagaa atgtcttcag actatccgcc
     7621 gcgccaaccg cctgcgcctt agcatgataa aacgtgccga ggtcgcgtaa tggctggaaa
     7681 aactccggcg cgaggatcaa ggcgaggaac ccggcggcga gcgtcacacc ggtaccgtaa
     7741 tgaccaaagt tcagctcgcc caggtaagag aagccaaaat aaacggcgac cagcgcaata
     7801 gaaagcgagg tgaaaaattc cagcacgccg gaagataaaa aggcgaggcg cagtacttcc
     7861 atcgtgcgct gacgaaaatc ctgcgatgct gcgcgaatgc tctcggtttc cgcttctcca
     7921 cgaccgaaaa ttcgcagcgt ttccatcccg cgcagacggt caagaaaatg gccgcttagc
     7981 cgggcaagcg ccaggaaatt gcggcggttg gcgtcagccg cgcccatccc caccatcgcc
     8041 ataaataggg gaatgagcgg ggcagtgccc agcagaatca gcgccgccgc ccagtttgac
     8101 gggaaaatcg ccgccacgat taagagcggt acgcaaacgg caagcgccat ttgcggcaga
     8161 tagcgcgcat aatagtcatg catatcgtca atctgctcca acaccagcgt cgcccagcta
     8221 ccggcgggct tgccctgaat ccaggctggg ccggcttgct gcagacgatc caacacctga
     8281 cggcggatct caaagcgaat atgctgtccg gcatgaaaac cgacgcgctc gcgcaaccac
     8341 accacccagg cgcggaggac aaagatcagt atcagcagga taaaagggag caacagcgct
     8401 tcccgtggaa tgttctccat gatcatatgt tgcaggatac gcgccatgat ccaggcctga
     8461 gcgacaatta atacgccact catgaacccc aacaggcggg aaatattcaa ccaccgttgg
     8521 gagattacgc tttgctgttt taaccagcgg gtcagctctt tttgacgggt tttattcatt
     8581 gcacgcttag caggtgagtt attggaattt caggcagggc aatgttacaa cgacgcaaaa
     8641 ataaaggcga cttatagtcg ccttttttac ttttgttact gatttgtaaa aactatttgc
     8701 tcgcgtcggc cagaccatcg agatagcgtt cggcatccag cgccgccata cagcccgtac
     8761 ctgcagaggt gatcgcctga cggtaaatat gatccataac gtcacccgcc gcgaatacgc
     8821 cagggatgct ggtttgtgtg gcgttgccat gggtgccgga ctgaactttg atataaccat
     8881 tttccagctc aagctggcct tcgaagagtg ccgtgtttgg gctatgaccg atggctacga
     8941 aaagtccggc gatgtccagc gtctcgatat tatcgctctg ctgcgtgtcg cgaagacgca
     9001 gaccagtaac gcccatctga tcgccggtca cttcttccag cgtccggttg gtgtgcagga
     9061 tgatattgcc attttcgact ttatccatca ggcgcttaat gaggattttt tcagcgcgga
     9121 aaccgtcacg gcgatggata aggtgcactt ccgaagcgat gttggacaga taaagcgctt
     9181 cttcaactgc ggtgttgccg ccgccgatca ccgccacttt ctgattgcgg tagaagaaac
     9241 cgtcgcaggt tgcgcaggcg gaaacgccgc gccctttaaa ggcttcttcc gatggcagcc
     9301 ccagatagcg cgcggaagcg ccggtcgcaa tgatcaacgc atcacaagtg tactctgcgc
     9361 tgtcacctgt cagacggaac ggacgatttt gcagatccac gttgttgatg tgatcaaaaa
     9421 ttatctcggt ttcaaatttt gccgcatgtt catgcatgcg ttccatcagc agcgggccgg
     9481 tcaaatcgtt tggatcgccg ggccagtttt ccacttccgt cgtggtagtc agttgaccgc
     9541 ctttttccat accggtaata agtactggct gtaaatttgc gcgcgcggca tacaccgccg
     9601 cggtatatcc cgccggtcct gagcccagaa taagcagctt actgtgtttg gtcgtgccca
     9661 tgagatcccc atagttgttg gcagacaatg agcagaattg tagagaattt acagacgtaa
     9721 aaaaagagca taacgatttt gttaacaata tgtgtaatag catgaaccga tgaacgaccg
     9781 cggcagcgac gttatcatca caaactttaa ttaaaatcgg taacttataa ggtgacgaaa
     9841 tgacagttta ccgccctctc taatgaataa ctggcatgtt gtactaaaaa tcgatgtttt
     9901 gctttgacaa tcacctgctg ttttgcgaaa acattcgagg aagaaaaaaa ctgtgttatg
     9961 tatgtgctgc ataatcatgc atgtaaatac catgtttacc gggctagtga aatctacgca
    10021 tggcgtggac agacgccatt cgtgatgtcg atagctgccg cgaggcaacg gtcttctcac
    10081 catagaccag gcattgcacg ccgttaatcc ctctgggttt cggtctattg tgatgggcag
    10141 cgactctgaa cagtgatgtg agtagagtca ggcaggagta gggaaggaat acagagagac
    10201 aataataatg gtagatagca agaagcgccc tggcaaagat ctcgaccgta tcgatcgtaa
    10261 cattcttaat gaactgcaaa aggatgggcg tatttccaac gtcgagcttt ctaaacgagt
    10321 aggactttcg ccgacacctt gccttgagcg tgtgcgtcgg ctggagcgac aggggtttat
    10381 ccagggctat acggcgctgt tgaacccgca ttatctggat gcgtcacttc tggtattcgt
    10441 tgagattacc ttaaatcgcg gcgcgccgga tgtgtttgaa cagtttaatg ccgccgtgaa
    10501 aaagcttgaa gagattcagg agtgtcattt ggtttccggc gatttcgact acctgttgaa
    10561 aacccgtgta ccggatatgt cagcgtatcg aaaactattg ggagagacgt tgctgcgctt
    10621 gccaggtgtg aacgacaccc gaacttacgt agtgatggaa gaggtaaaac agagtaatcg
    10681 tctggttatt aagacacgct aacacggaac aggtgcaaaa tcgccgtagt ttgattacac
    10741 tcctgttaat ccatacagca acagtgccgg ggcaacccgg tgctgttgtc cgttttagca
    10801 tcgggcggga aaagcctgga acctggagag ccttttttga gccaggaata tactgaagac
    10861 aaagacgtca cattgacgaa gttaagcagc gggcgccgac ttctggaagc gttgttgata
    10921 cttattgccc tttttgccgt ctggttgatg gcggccttgt tgagctttaa cccttcggac
    10981 cccagttggt cgcaaaccgc ctggcatgaa cccatccata atttaggcgg cgcgccgggc
    11041 gcgtggctgg ccgatacact gttctttatt tttggcgtaa tggcctacac tatccctgtc
    11101 attattgtcg gcgggtgttg gtttgcgtgg cgtcatcagt ctacggatga ttacatcgac
    11161 tattttgctg tgtcgctacg ccttattggc gtgctggcgc tgattctcac ttcctgcggt
    11221 ctggcggcca ttaatgccga cgatatctgg tatttcgcct ccggcggcgt aattggcagc
    11281 ctgttaagca ccacgctgca gccgttgttg catagtagcg gcggaacgat aatgcttctc
    11341 tgtatttggg ctgccgggct gacgctcttt accggctggt cctgggttag tatcgccgaa
    11401 aaattaggcg gctggctgct taatatactg accttcgcca gcaaccgtac ccggcgtgat
    11461 gatacgtggg ttgacgacga agagtatgat gacgaatacg atgaagaaac cgatggcgtg
    11521 cagcgtgaat ctcgccgggc gcgtattttg cgcggcgcgt tggcgcgtcg taagcgactg
    11581 gctgaaaaat tcagcaatcc acggggccgt cagaccgatg ccgcgctctt ttccggcaaa
    11641 cggatggatg atgacgagga cattcagtat agcgcgcgcg gcgtcgctgc cgatcccgac
    11701 gacgttctgt tttcgggcaa ccgtgcgacg cagtcggaat atgatgaata tgatccgctg
    11761 ttaaacggcc attctgtcac cgaaccggtc gccgccgctg cggccgcaac tgccgtcacc
    11821 cagacgtggg cagcgtccgc cgatcccata atgcaaacgc cgcccatgcc gggggctgag
    11881 ccggttgtcg cgcaaccgac cgtggagtgg cagcccgtac cggggccgca aaccggcgaa
    11941 ccggttatcg cgcctgcgcc ggaggggtat cagccgcatc cgcaatatgc tcaaccgcag
    12001 gaggcgcaaa gtgcgccgtg gcagcaacct gtgcctgtcg cttccgcgcc gcaatacgcc
    12061 gcgacgccag cgaccgcagc agaatatgac tctcttgcgc cgcaggaaac acagccgcaa
    12121 tggcaggcgc cggatgccga acaacactgg cagccggagc cgatagcggc tgaaccttcc
    12181 cacatgccgc cgccggttat cgaacagccg gttgccaccg agcctgaacc tggcatagaa
    12241 gagaccaggc ccgctcgccc tccgctttac tattttgaag aggtggaaga gaaacgcgcc
    12301 cgtgagcgcg aacaactggc ggcatggtat caaccgattc cggagccggt aaaagagaac
    12361 gtgccggtca aacctacggt atctgtcgcg ccgtccatac cgccagtgga agcggtagcc
    12421 gccgccgcgt cgcttgacac aggtattaag agtggcgccc tggcagcagg cgccgcggcc
    12481 gctgcgcctg catttagtct ggctaccggc ggcgcgccgc gtccgcaggt gaaagagggg
    12541 attggtccgc aactgccgcg tccgaaccgc gttcgcgtgc cgacccgacg ggaactggca
    12601 tcgtacggta ttaagctgcc gtcacagagg attgctgaag aaaaagcccg cgaggcggag
    12661 cgcaatcagt acgagacggg cgcgcagcta accgatgaag aaatagatgc aatgcatcag
    12721 gacgagttag cccgtcagtt tgcgcagtcg cagcagcatc gttatggtga gacgtatcag
    12781 catgatactc aacaggcaga agatgacgat accgctgcgg aagctgaatt agcccgccag
    12841 tttgccgctt cgcaacagca gcgctattcc ggcgagcaac ccgctggcgc gcagccgttc
    12901 tcactggacg atctggattt ctcgccaatg aaagtattgg ttgatgaagg tccgcacgaa
    12961 ccgctgttca cgccgggtgt catgcccgag tcaacgcctg ttcagcaacc tgtagcgccg
    13021 cagccgcagt atcagcagcc ggtagcgccg cagccacagt atcagcagcc gcagcagccg
    13081 gtagcgtcgc agccacagta tcagcagccg caacagccgg tagcgcctca gccgcagtat
    13141 cagcagccgc agcagccggt agcgccgcag ccgcagtatc agcagccgca acagccggta
    13201 gcgccgcagc cgcagtatca gcaaccgcaa cagccggtag cgccgcagcc acagtatcag
    13261 cagccgcaac agccggtagc gcctcagccg cagtaccagc agccgcagca accgacagcg
    13321 ccgcaagaca gtctgatcca cccgctgttg atgcgtaacg gcgacagtcg tccattgcag
    13381 cgtccgacga cgccgctgcc ttcattagat cttctgacgc cgccgccgag cgaagttgaa
    13441 ccggtagata cctttgcgct ggaacaaatg gcgcgtctgg ttgaagcgcg tctggcggat
    13501 ttccgcatta aagctgatgt ggtgaactat tcgccaggcc cggtcattac tcgctttgaa
    13561 ctgaatctgg ccccgggcgt taaagcagcg cgtatctcca acctttcccg ggatctggcg
    13621 cgctccttgt caacggtagc cgtacgcgtt gtggaagtca ttccaggcaa accttacgta
    13681 gggttggaat tgccgaacaa gaaacggcaa accgtttatc tgcgcgaagt gttggataac
    13741 gccaaattcc gcgagaatcc gtcgccgctt accgtggtgt taggtaagga tatcgcgggc
    13801 gatccggtag tggcggatct ggcgaaaatg cctcacctgc tggtggccgg tacgaccggt
    13861 tccggtaagt cggtcggggt taacgccatg atcctcagta tgctgtataa agcgcagccg
    13921 gaagacgttc gctttatcat gatcgacccg aaaatgttag aactctcggt ctatgaaggt
    13981 ataccgcatc tgctgacgga agttgttacc gatatgaaag acgcagctaa cgcgttacgc
    14041 tggagcgtca atgagatgga gcgtcgctat aagctgatgt ccgcgctcgg cgtgcgtaat
    14101 ctggctggtt ataacgagaa aatcgccgaa gcggcccgca tgggacgtcc gattccggac
    14161 ccgtactgga agccgggcga cagtatggat gttcagcatc cggttctgga aaaactgccg
    14221 tatatcgtgg tactggttga tgaatttgcc gacctgatga tgaccgtcgg taaaaaagtt
    14281 gaagagctga tcgcgcgttt ggcgcagaaa gcgcgcgctg cggggattca cctggtactg
    14341 gcgacgcagc gtccgtcggt cgatgtgatt actggtttaa ttaaagccaa cattccaacc
    14401 cgtatcgctt ttacagtatc cagcaagatc gactcccgca ccattcttga tcagggtggc
    14461 gctgagtcgt tattgggaat gggggacatg ctctattccg gaccaaactc caccatgccg
    14521 gtacgtgtcc atggggcgtt tgtgcgtgac caggaagtcc atgcggtggt gcaggactgg
    14581 aaagcgcgcg gtcgtccgca atatgtggat ggcattacct ccgacagcga aagcgaaggt
    14641 ggcggtggcg gttttgacgg cggcgaagaa ttagatgcgc tattcgatca ggccgttaat
    14701 ttcgtcactc agaagcgaaa agcgtccatt tccggcgttc agcgtcagtt ccgtatcggc
    14761 tataaccgtg cggcgcgtat tatcgaacag atggaagcgc agggtattgt cagcgctcag
    14821 gggcataacg gtaatcgcga agtgttggct ccgccgcctt ttgagtaaac ctgtaaaccg
    14881 gatggcgctg ttcagaggct gccatccggc aacaaaattc agtattttct tctttcctca
    14941 tgctgatttt tggcctggaa tagaaagcaa aaggagctcc tggtcgggag tgtcgaaact
    15001 tgaggaataa tgatgaaaaa aatggcaatc gcctgtgcat tactttcaag cgttgtagcc
    15061 agcagcgtat gggctgacgc cgccagctct ctgaaaagcc gtctggataa agtgagcagc
    15121 tttcatgcca cctttactca aaaagtcacc gatggcagcg gtgccgcggt gcaggaggga
    15181 cagggtgatt tatgggttaa gcggccaaat ctattcaact ggcatatgac gcaacctgac
    15241 gagagtattc tggtttctga cggcaaaacg ttatggttct ataacccgtt tgtagaacag
    15301 gctaccgcca cgtggttgaa agatgccacc ggaaatacac cgtttatgct gattgcccgc
    15361 aaccaggcca gcgactggca gcagtataat attaagcagg atggcgataa ttttgtgctg
    15421 acgccgaaag ccagcaacgg caatctgaaa cagttcacca tcaatgtggg acgcgacggg
    15481 actatccacc agtttagcgc cgtagaacaa gacgatcagc gtagcgccta tcagctaaaa
    15541 tcccagcaaa acggcgctgt tgaaccgtca aaatttacgt ttactccgcc gcaaggggta
    15601 acgatagacg accaacgtaa gtagaggcga tgagtgagca atctgtcgct cgatttttct
    15661 gataatacgt ttcaaccgct ggccgcgcga atgcggccgg aaaatttagc acagtatatc
    15721 ggccagcagc atttgctggc cgcaggtaag ccgttgcctc gcgctattga ggccgggcat
    15781 ctgcactcca tgattttatg ggggccgcca gggacgggga aaaccacgct cgctgaagtg
    15841 atcgcccgct acgccagcgc cgatgtcgag cgtatttccg ccgtcacttc tggggtaaaa
    15901 gagattcgcg aagctatcga gcgcgcccgc cagaatcgta atgccggtcg ccgtaccatc
    15961 ctgtttgtcg atgaagtgca tcgctttaac aaaagccagc aggacgcctt tttaccgcat
    16021 atcgaagatg gcactatcac ctttatcggc gcgaccacgg aaaatccctc ttttgagctg
    16081 aactcggcgc tattgtcgcg agcgcgagtc tatctgctga aatcgttgac tactgacgat
    16141 attgagcaag tactggacca ggcgatgcag gacaaaacgc gtggttacgg cgatcaggat
    16201 atcgtgttac cggatgagac acggcgagcg attgctgagc tggtcaatgg cgacgcgcgg
    16261 cgcgccttaa atacgctgga aatgatggct gatatggcgg aggcggatga cagcggcaaa
    16321 cgcgttttat tgcccgcctt gttgaccgag atcgccggcg agcgcagcgc gcgttttgat
    16381 aacaaaggcg atcgcttcta cgatcttatt tccgccttac ataaatcagt gcgcggcagc
    16441 gcgccggatg ccgccctcta ttggtatgcc cgtatcatta ccgcgggagg cgatccgctg
    16501 tacgtggcgc gtcgctgcct ggcgattgcc tcggaagatg tgggtaatgc cgatcctcgc
    16561 gcgatgcagg tcgccattgc cgcgtgggat tgtttcaccc gcgtcggccc ggctgaaggc
    16621 gaaagggcga tcgcgcaggc tatcgtttat ctcgcctgcg cgccgaagag caacgccgtc
    16681 tataccgcct ttaaggctgc gctggccgac gcgcgcgaac gtcctgatta tgacgttcct
    16741 gtccatctgc gtaatgcgcc aaccaaactg atgaaagaga tgggctatgg ccaggaatac
    16801 cgctatgccc acgatgagcc caatgcctat gctgcgggtg aagtgtactt cccgccggaa
    16861 atcgcgcaaa cgcgctatta tcatccgaca aatcgtggtc tggaaggtaa gattggcgaa
    16921 aagctcgcct ggctggctga acaggatcaa aatagcccca caaaacgcta ccgctagtgt
    16981 aaacgttgcg gtaaggttat ctctaaatat gatgctccag gtatcatggc gttgatgatg
    17041 aacctcgtta tgcctgatag cacgttgctt atgaggtccg cgggtatagc gcaatggatg
    17101 cgttgttgct gtcgtcggtc aggtaaggcg aaaacgtcgc tattacgtaa acggggttta
    17161 cgttcatcaa tacaatcaga ggcgatcatc aattgatcgc gtttcctttt attattcgat
    17221 aagcacagga taagcatgct cgatcccaat ctgctgcgta atgagccaga cgcagtcgct
    17281 gaaaaactgg cacgccgggg ctttaagctg gatgtagata agctgcgcgc tcttgaagag
    17341 cgtcgtaaag ttttgcaggt caacacggaa aacctgcagg cggagcgtaa ttctcgatcg
    17401 aaatccatcg gccaggcgaa agcgcgcggg gaagatatcg agcctttacg cctggaagtg
    17461 aataaactgg gcgaagagtt ggatgcggcg aaagccgagc tggatacctt gctggcggag
    17521 atccgcgata tcgcgctgac catcccaaac ctgcctgcgg atgaagtgcc ggtaggtaaa
    17581 gatgaaaacg acaacgttga agtcagccgc tggggtaccc cgcgtgagtt tgattttgaa
    17641 atccgcgatc acgtcacctt aggggaaatg cactccggcc tcgactttgc cgctgcggtt
    17701 aagctgaccg gctcccgctt tgtggtgatg aaaggacaga ttgcgcgtat gcatcgcgca
    17761 ttgtcgcagt tcatgttgga tctgcatacg gaacagcacg gctatagcga aaactacgtg
    17821 ccgtatctgg ttaaccacga cacgctgtat ggcaccggtc aactgccgaa attcgcaggc
    17881 gacttgttcc atacccgtcc gctggaagaa gaagcagaca gcagtaacta tgctttgatc
    17941 ccgacggcgg aggttccgct gaccaatctg gtacgcgatg aaatcatcga cgaagatcag
    18001 ctgccgatta aaatgacggc gcatacgcct tgtttccgtt ctgaagcagg ttcttatggt
    18061 cgtgataccc gcggcctgat tcgtatgcat cagtttgaca aagttgagat ggtgcagatc
    18121 gttcgcccgg aagattctat ggctgcgttg gaagagatga ccggccacgc ggaaaaagtg
    18181 ctccagctac tgggactgcc gtaccgtaaa atcattctgt gcactggcga tatgggcttc
    18241 ggcgcctgca aaacttatga cctcgaagtc tgggttccgg cgcagaatac ctaccgcgag
    18301 atctcttcct gctctaacgt ctgggacttc caggcgcgtc gtatgcaggc acgctgtcgc
    18361 agcaagtccg acaaaaagac ccgtctggtc cataccctga atggttctgg tctggcggta
    18421 ggtcgtaccc tggtggctgt gatggaaaac tatcagcagg ctgatggtcg tattgaagtg
    18481 ccggaagtat tacgtccgta catgaacgga ctggaatata tcggctaatc ctcgctttct
    18541 cctcttctaa aaagcgcctg cgggcgcttt ttttatgcca gtttgatacc ggacaataat
    18601 ccctacccta ttaggggtaa tactgatttc gaatgaaggt cagtttttaa cgc
//
LOCUS       DAJVBX010000077        18584 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.077, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000077 DAJVBX010000000
VERSION     DAJVBX010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 18584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18584
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.077"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..586)
                     /gene="rsmG"
                     /locus_tag="OPV72_002307"
     CDS             complement(<1..586)
                     /gene="rsmG"
                     /locus_tag="OPV72_002307"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462772.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HCR9914587.1"
                     /translation="MLNKLSRLLADAGISLTDHQKTLLVAYVDMLHKWNKAYNLTSVR
                     DPNEMLVRHILDSIVVAPYLQGQRFIDVGTGPGLPGIPLAIVLPDAHFTLLDSLGKRV
                     RFLRQVQHELKLENITPVQSRVEAYPSEPPFDGVISRAFASLNDMVSWCHHLPGEKGR
                     FYALKGQLPGDEIASLPDNFSVESVEKLRVPQLEG"
     gene            complement(689..2578)
                     /gene="mnmG"
                     /locus_tag="OPV72_002308"
     CDS             complement(689..2578)
                     /gene="mnmG"
                     /locus_tag="OPV72_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HCR9914588.1"
                     /translation="MFYQDPFDVIIIGGGHAGTEAAMAAARMGQQTLLLTHNIDTLGQ
                     MSCNPTIGGIGKGHLVKEVDALGGLMAKAIDQAGIQFKILNASKGPAVRATRAQADRV
                     LYRQAVRIALENQPNLMIFQQAVEDLIVENDRVVGAVTQMGLKFRAKAVVLTVGTFLD
                     GKIHIGLDNYSGGRAGDPPSIPLSRRLRELPLRVSRLKTGTPPRIDARTIDFSVLAQQ
                     HGDNPMPVFSFMGNAFQHPQQVPCYITHTNEKTHDVIRNNLDRSPMYAGVIEGIGPRY
                     CPSIEDKVMRFADRNQHQIFLEPEGLTSNEIYPNGISTSLPFDVQMQIVRSMQGMENA
                     KIVRPGYAIEYDFFDPRDLKPTLESKFIHGLFFAGQINGTTGYEEAAAQGLLAGLNAA
                     RLSADKEGWAPARSQAYLGVLVDDLCTLGTKEPYRMFTSRAEYRLMLREDNADLRLTE
                     MGRELGLVDDERWARFNEKLENIERERQRLKSTWVTPSAESADEVNAHLTTPLSREAS
                     GEDLLRRPEMTYAQLTSLAAFAPALEDEQAAEQVEIQVKYEGYIARQQDEIEKQLRNE
                     NTLLPATLDYRQVSGLSNEVIAKLNDHKPASIGQASRISGVTPAAISILLVWLKKQGM
                     LRRSA"
     gene            complement(2957..3400)
                     /gene="mioC"
                     /locus_tag="OPV72_002309"
     CDS             complement(2957..3400)
                     /gene="mioC"
                     /locus_tag="OPV72_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein MioC"
                     /protein_id="HCR9914589.1"
                     /translation="MADITLISGSTLGGAEYVAEHLAEKLEAAGFSTETVHGPLLEDL
                     STSGIWLIISSTHGAGDIPDNLTPFYEDLQTQKPDLSAVRFGAIGIGSREYDTFCGAI
                     EKIEAELKGAGAKQVGETLKINILEHEIPEDPAEIWLGSWINLLK"
     gene            complement(3490..3948)
                     /gene="asnC"
                     /locus_tag="OPV72_002310"
     CDS             complement(3490..3948)
                     /gene="asnC"
                     /locus_tag="OPV72_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator AsnC"
                     /protein_id="HCR9914590.1"
                     /translation="MENYQIDNLDRGILDALMENARTAYAELAKQFGVSPGTIHVRVE
                     KMKQAGIITGARIDVSPKQLGYDVGCFIGIILKSAKDYPSALARLESLDEVTEAYYTT
                     GHYSIFIKVMCKSIDALQHVLINKIQTIDEIQSTETLIVLQNPIMRTIKP"
     gene            4099..5091
                     /gene="asnA"
                     /locus_tag="OPV72_002311"
     CDS             4099..5091
                     /gene="asnA"
                     /locus_tag="OPV72_002311"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HCR9914591.1"
                     /translation="MKTAYIAKQRQISFVKSHFSRQLEERLGLIEVQAPILSRVGDGT
                     QDNLSGCEKAVQVKVKALPDAQFEVVHSLAKWKRQTLGQHDFSAGEGLYTHMKALRPD
                     EDRLSPLHSVYVDQWDWERVMGDGERQFSTLKSTVEAIWAGIKATEAEVHKQFGLAPF
                     LPDQIHFVHSQELLARFPDLDAKGRERAIAKELGAVFLVGIGGKLSDGRRHDVRAPDY
                     DDWSSASELGYAGLNGDILVWNPVLEDAFELSSMGIRVDADTLMRQLALTGDEDRLQL
                     EWHQALLRGEMPQTIGGGIGQSRLTMLLLQLPHIGQVQCGVWPAQVRESIPAIL"
     gene            complement(5096..6547)
                     /gene="viaA"
                     /locus_tag="OPV72_002312"
     CDS             complement(5096..6547)
                     /gene="viaA"
                     /locus_tag="OPV72_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase RavA stimulator ViaA"
                     /protein_id="HCR9914592.1"
                     /translation="MLTLDTLNTMLAVSEEGMVEEMILALLASPQLVIFFEKFPRLKN
                     AVTADLPRWREALRSRLKDARVPPELTEEVMCYQQSQLLSTPQFIVQLPQILALLHRL
                     HSPYAAQAKQLTESNSTFTPALHTLFLQRWRLSLVVQATTLNQQLLEEEREQLLSDVQ
                     ERMTLSGQLEPTLAENDNAAGRLWDMSAGQLKRGDYQLIVKYGEFLAAQPELMQLAEQ
                     LGRSREAKSVPKKDAPMETFRTLVREPATVPEQVDGIQQGDDILRLLPPELATLGITE
                     LEYEFYRRLVEKQLLTYRLHGEAWREKVTERPVVHQDVDEQPRGPFIVCVDTSGSMGG
                     FNEQCAKAFCLALMRVALADNRRCFIMLFSTDVVRYELSGPESIEQAIRFLSQRFRGG
                     TDIASCFRAIIERMQGREWFDADAVVISDFIAQRLPDDVVSKVGELQRLHQHRFHAVA
                     MSAHGKPGIMRIFDHIWRFDTGMRSRLLRRWRR"
     gene            complement(6541..8037)
                     /gene="ravA"
                     /locus_tag="OPV72_002313"
     CDS             complement(6541..8037)
                     /gene="ravA"
                     /locus_tag="OPV72_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase RavA"
                     /protein_id="HCR9914593.1"
                     /translation="MAHPHLLAERISRLSSALEKGLYERSHAIRLCLLAALSGESVFL
                     LGPPGIAKSLIARRLKFAFQRARAFEYLMTRFSTPEEVFGPLSIQALKDEGRYERLTT
                     GYLPEAEIVFLDEIWKAGPAILNTLLTAINERHFRNGAFEEKIPMRLLVAASNELPEA
                     DSSLEALYDRMLIRLWLDKVQDKANFRSMLVSQQDESDNPVPASLQVSDEEYQQWQKD
                     IGAISLPDPVFELIFTLRQQLDNLPNAPYVSDRRWKKAIRLLQASAFFSGRDAVAPID
                     LILLKDCLWYDAQSLNLMQQQLEILMTGHAWQQQAMLTRLGGIVQRRLQLQQQQSDKT
                     AFTVIKEGGMFSRRPHYTLPPEASASTLTLLLQKPLKLHDMEVIHITFDRSALELWLT
                     KGGEIRGKLNGIGFAQTLNMEVDNAQHPVVRDISLQGTRLALPGAAEDSMPAEIKQQL
                     ETLENDWRQQHTRFSEQQHCLFIHSDWLGRIEASLQDVGEQIRQAQQC"
     gene            8385..10253
                     /gene="kup"
                     /locus_tag="OPV72_002314"
     CDS             8385..10253
                     /gene="kup"
                     /locus_tag="OPV72_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000102304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low affinity potassium transporter Kup"
                     /protein_id="HCR9914594.1"
                     /translation="MSTDNKQSLPAITLAAIGVVYGDIGTSPLYTLRECLSGQFGFGV
                     ERDAVFGFLSLIFWLLIFVVSIKYLTFVMRADNAGEGGILTLMSLAGRNTSARTTSML
                     VIMGLIGGSFFYGEVVITPAISVMSAIEGLEIVAPQLDTWIVPLSIIVLTLLFMIQKH
                     GTGMVGKLFAPIMLTWFLILAVLGLRSIIANPEVLHALNPVWAVRFFLEYKTVSFIAL
                     GAVVLSITGVEALYADMGHFGKFPIRLAWFTVVLPSLVLNYFGQGALLLKHPEAIKNP
                     FFLLAPDWALIPLLILAALATVIASQAVISGVFSLTRQAVRLGYLSPMRIIHTSEMES
                     GQIYIPFVNWLLYFAVVVVIVSFEHSSNLAAAYGIAVTGTMVLTSILSTTVARKNWHW
                     NKYFVALILIAFLCVDIPLFSANLDKLLSGGWLPLSLGLIMFTIMTTWKSERFRLLRR
                     MHEHGNSLEAMIASLEKSPPVRVPGTAVYMSRALSVIPFALLHNLKHNKVLHERVILL
                     TLRTEDAPYVHNVRRVQIEQLSPTFWRVVASYGWRETLNVEEVFHRCGLEGLSCRMME
                     TSFFMSHESLIVGKRPWYLRLRGKLYLLLQRNALRAPDQFEIPPNRVIELGTQVEI"
     gene            10470..10889
                     /gene="rbsD"
                     /locus_tag="OPV72_002315"
     CDS             10470..10889
                     /gene="rbsD"
                     /locus_tag="OPV72_002315"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HCR9914595.1"
                     /translation="MKKGTVLNSEISSVISRLGHTDTLVVCDAGLPIPNSTARIDMAL
                     TQGVPSFMQVVDVVTWEMQVEAAILATEIKQQNPQLHETLLTHLEQLQQHQGNTIKIS
                     YTTHEQFKKLTADSQAVIRSGECSPYANVIICAGVTF"
     gene            10897..12402
                     /gene="rbsA"
                     /locus_tag="OPV72_002316"
     CDS             10897..12402
                     /gene="rbsA"
                     /locus_tag="OPV72_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter ATP-binding protein RbsA"
                     /protein_id="HCR9914596.1"
                     /translation="MDALLQLKGIDKAFPGVKALSGAALNVYPGRVMALVGENGAGKS
                     TMMKVLTGIYTRDAGSLLWLGKETTFNGPKSSQEAGIGIIHQELNLIPQLTIAENIFL
                     GREFVNRFGKIDWKKMYAEADHLLAKLNLRFKSDKLVGELSIGDQQMVEIAKVLSFES
                     KVIIMDEPTDALTDTETDSLFRVIRELKSQGRGIVYISHRMKEIFEICDDVTVFRDGQ
                     FIAEREVATLTEDSLIEMMVGRKLEDQYPHLDNAPGEIRLKVDNLCGPGVNDVSFVLR
                     KGEILGISGLMGTGRTELMKVLYGAMPRTSGYVTLEGHEVVTRSPQDGLANGIVYISE
                     DRKRDGLVLGMSVKENMSLTALDYFSRAGGSLKHKDEQQAVGDFIRLFNVKTPSMEQA
                     IGLLSGGNQQKVAIARGLMTRPKVLILDEPTRGVDVGAKKEIYQLINQFKADGLSIIL
                     VSSEMPEVLGMSDRIIVMHEGHLSGEFTREQATQEVLMAAAVGKLNRVNQE"
     gene            12408..13373
                     /gene="rbsC"
                     /locus_tag="OPV72_002317"
     CDS             12408..13373
                     /gene="rbsC"
                     /locus_tag="OPV72_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002882531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter permease"
                     /protein_id="HCR9914597.1"
                     /translation="MTTQAVSGRRYFTKAWLLEQKSLIALLVLIAIVSTLSPNFFTVN
                     NLFNILQQTSVNAIMAVGMTLVILTSGIDLSVGSLLALTGAVAASIVGVEVNALVAVA
                     AALALGAAIGAVTGVIVAKGRVQAFIATLVMMLLLRGVTMVYTDGSPVNTGFTDNADL
                     FGWFGIGRPLGVPTPVWIMAIVFIAAWYMLHHTRLGRYIYALGGNEAATRLSGISVSK
                     VKIIVYSLCGLTASLAGIIEVARLSSAQPTAGTGYELDAIAAVVLGGTSLAGGKGRIV
                     GTLIGALILGFLNNGLNLLGVSSYYQMIVKAVVILLAVLVDNKKQ"
     gene            13398..14288
                     /gene="rbsB"
                     /locus_tag="OPV72_002318"
     CDS             13398..14288
                     /gene="rbsB"
                     /locus_tag="OPV72_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter substrate-binding protein
                     RbsB"
                     /protein_id="HCR9914598.1"
                     /translation="MNMKKLATLVSAVALSATVSANAMAKDTIALVISTLNNPFFVSL
                     KDGAQKEADKLGYNLVVLDSQNNPAKELANVQDLTVRGTKILLINPTDSDAVGNAVKM
                     ANQAKIPVITLDRQATKGDVVSHIASDNVLGGKIAGDYIAKKAGEGAKVIELQGIAGT
                     SAARERGEGFQQAVAAHKFNVLASQPADFDRTKGLNVMQNLLTAHPDVQAVFAQNDEM
                     ALGALRALQTAGKADVMVVGFDGTPDGEKAVKDGKLAATIAQLPDQIGAKGVEVADKV
                     LKGEKVQAKYPVDLKLVIKQ"
     gene            14421..15350
                     /gene="rbsK"
                     /locus_tag="OPV72_002319"
     CDS             14421..15350
                     /gene="rbsK"
                     /locus_tag="OPV72_002319"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HCR9914599.1"
                     /translation="MKTAGNLIVLGSINADHILNLESFPTPGETVTGSHYQVAFGGKG
                     ANQAVAAGRSGANIAFIACTGDDDIGDSIRKQLVSDRIDIAPVSVIKGESTGVALIFV
                     NGEGENVIGIHAGANAALSPALVDAQRERIAQADALLMQLESPLESVLAAAKIAHQHH
                     TTVALNPAPARELPDELLALVDIITPNETEAEKLTGVRVENDDDVAKAAQVLHDKGIR
                     TVLITLGSRGVWASVNGEGRRVPGFSVEAVDTIAAGDTFNGAFITAILEETPLPEAIR
                     FAHAAAAIAVTRKGAQPSVPWREEIEAFLHQQG"
     gene            15354..16352
                     /gene="rbsR"
                     /locus_tag="OPV72_002320"
     CDS             15354..16352
                     /gene="rbsR"
                     /locus_tag="OPV72_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose operon transcriptional repressor RbsR"
                     /protein_id="HCR9914600.1"
                     /translation="MATMKDVARLAGVSTSTVSHVINKDRFVSETITEKVEAAIKSLN
                     YAPSALARSLKLNQTRTIGMLITASTNPFYSELVRGVERSCFERGYSLVLCNTEGDEQ
                     RMNRNLETLMQKRVDGLLLLCTETHQPSREIMERYPSIPTVMMDWSPFDGEGDSDLIQ
                     DNSLLGGDLATQHLIDKGFTRIACITGPLDKTPARLRLEGYRAAMKRAGLAIPQGYEI
                     TGDFEFGGGFDAMQALLAHQQRPQAVFTGNDAMAVGAYQALYQAGLRIPQDMAVIGYD
                     DIELARYMTPPLTTIHQPKDELGELAIDVLIHRMAQPALQQQRLQLTPVLTVRGSV"
     gene            complement(16318..17745)
                     /gene="mdtD"
                     /locus_tag="OPV72_002321"
                     /pseudo
     CDS             complement(16318..17745)
                     /gene="mdtD"
                     /locus_tag="OPV72_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462786.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter subunit MdtD"
     gene            complement(17757..18461)
                     /locus_tag="OPV72_002322"
     CDS             complement(17757..18461)
                     /locus_tag="OPV72_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HCR9914601.1"
                     /translation="MPLSAQQLAAQKNLSYVLAEKLAQRILKGDYAPGTILPGEIELG
                     EQYGVSRTAVREAVKTLTAKGMVLPRPRIGTRVMPQGNWNFLDQELLTWWMTEENFHQ
                     VVDHFLVMRISLEPQACLLAATLGTPEQKARLNALMEEMVALKKHFKRERWIEVDMAW
                     HEHIYEMSANPFLISFATLFHSVYHTYFTSITYNEVVKLDLHQAIVDAIADGDGERAF
                     QACQALLIAPNERPDN"
BASE COUNT         4262 a         4770 c         5089 g         4463 t
ORIGIN      
        1 cgccttccag ttgcggaacg cgtaattttt caacagattc gacgctaaaa ttgtcaggta
       61 gtgaggcaat ttcatcccct ggcaattgcc cttttaaggc ataaaaacgt cctttctctc
      121 ccggcagatg gtgacaccag ctcaccatat cattcaacga tgcgaaagcg cggctgataa
      181 cgccatcaaa cggcggttcg gagggatagg cttcaacgcg gctttgaacc ggcgtgatgt
      241 tttccagttt cagttcgtgc tggacctgac gcagaaaacg tacccgcttg cccaggctgt
      301 cgagtaaggt gaaatgcgcg tcagggagaa caatagccag cgggatgccc ggcagccccg
      361 gtcctgttcc tacatcgata aaacgctgtc cctgcagata cggcgcaacg actatgctgt
      421 cgagaatatg gcgtaccaac atttcgttgg gatcccgcac tgacgtcagg ttgtatgctt
      481 tgttccattt gtgcagcata tcaacgtagg cgaccagcag cgttttctgg tgatcggtaa
      541 gagaaatacc ggcatcagcc agcagacgag agagtttgtt gagcacggtc attacctgtt
      601 aataatcaaa tgcccgatgc gctttcgctt atcgggccta caaatttgta gggcgggcaa
      661 gcgaagcgcc cccgccaaat tagtgttatc aagcgctacg acgcagcata ccttgttttt
      721 tcagccatac cagcagaatg gagattgccg ctggcgtaac gccggagata cgcgatgcct
      781 ggccgataga cgccggttta tgatcgttca gcttggcgat aacttcgttc gacagaccgg
      841 aaacctgacg ataatccagc gtggcaggca gcaacgtatt ctcgttacgt agttgttttt
      901 caatctcatc ctgctggcga gcgatatagc cttcgtattt gacctggatt tccacctgtt
      961 cagcggcttg ctcatcttca agcgcaggcg cgaatgcggc aagcgaagtg agctgcgcat
     1021 atgtcatttc cggacgacgc aacagatctt cgccgctggc ctcacgggag agtggcgtgg
     1081 tcaaatgcgc attcacttca tcagcggatt ccgcagacgg cgttacccat gtcgatttca
     1141 gccgctgacg ttcgcgttcg atattttcca gcttctcgtt gaagcgcgcc cagcgttcat
     1201 catccaccag acccagctcg cggcccattt cggtcagacg cagatcggcg ttgtcctcac
     1261 gcagcatcag gcgatattcg gcgcgggagg taaacatgcg atacggctct ttggtgccca
     1321 gcgtacagag atcgtccacc agcacgccga gataagcctg agaacgcgca ggcgcccagc
     1381 cctctttgtc ggcggaaaga cgcgcggcat tcagaccagc gagcaagccc tgcgccgcag
     1441 cctcttcata gccggtagta ccgttgattt gaccagcaaa gaacaggccg tgaataaatt
     1501 tactttccag agtcggtttc agatctcgcg ggtcgaagaa atcatactca atcgcgtaac
     1561 cagggcgaac gatcttcgcg ttctccatgc cctgcatgga acggacaatc tgcatctgca
     1621 cgtcaaacgg caggctggtg gagataccgt tagggtaaat ctcgttagag gtcagtcctt
     1681 ccggctcaag gaagatctga tgctggttac gatcggcaaa acgcatcacc ttgtcttcga
     1741 tcgaaggaca gtagcgtggg ccgatccctt cgatcacgcc agcgtacatt gggctacgat
     1801 cgaggttatt acgaatcacg tcatgggttt tctcattggt atgcgtgatg taacacggca
     1861 cctgttgcgg atgctgaaaa gcattcccca taaacgagaa aaccggcatc gggttatcgc
     1921 catgctgttg agccaacacg ctgaaatcga tagtacgcgc atcaatacgc ggcggtgtgc
     1981 cggttttcag gcggctgacg cgtagcggaa gctcacgcag acggcgagac agcgggatgg
     2041 atggcggatc gccagcacga ccgccgctgt agttatccag accaatatga attttgccgt
     2101 ccaggaaagt cccgacggtc agcaccaccg ctttcgcgcg gaatttgagc cccatttggg
     2161 tcacggcgcc gacaacgcga tcgttttcga caatcagatc ttcaaccgct tgctggaaga
     2221 tcatcagatt cggctgattc tccagcgcga tacgtaccgc ctggcgatat aagactcgat
     2281 ccgcctgagc tcgggtagcg cgaacggccg gacctttgct ggcgtttagt atcttaaact
     2341 gaatacctgc ctgatcgatc gctttcgcca tcagaccgcc gagcgcatcc acctctttta
     2401 ccagatgtcc cttgccaata ccgccgatcg tcgggttgca gctcatctgc cccaacgtgt
     2461 caatattgtg tgtcaaaagc agagtctgtt gacccatacg cgctgcggcc atcgcggcct
     2521 cagtgcctgc atgacccccg ccaataataa tgacgtcaaa aggatcctga taaaacatgg
     2581 taattgcctc gcataacgcg gtgtgaaaat ggattgaagc ccgggcggtg gattctactc
     2641 aactttagcc gatggagaaa gccccgggat ccgggctatt aaaaagaaga tctttttatt
     2701 tagagatctg ttctattgtg atctcttatt aggatcgcac caggctgtgg ataacccgga
     2761 tcctgtaata aagatcaatg cgttggaaag gatcactagc tgtgaatgat cggtgatcgt
     2821 ggcccgtata agctgggatc aaaacgggta cttatacaca actcaaaaag tgaacaaagg
     2881 ttattctttg gataactacc ggttgatcca agcttttcac catatttatc cacaatagat
     2941 cgcacgatct ttacacttat ttgagtaaat taatccagga tccgagccaa atctccgctg
     3001 gatcttccgg aatctcatgt tcaaggatgt tgatcttcag tgtttcccca acctgttttg
     3061 cgccagcgcc tttcagttcc gcttctattt tctcaatcgc gccgcaaaac gtgtcgtatt
     3121 ctcgactgcc aatgccaatt gcgccgaaac gtaccgcgga aagatcgggt ttctgcgtct
     3181 gaaggtcttc atagaaaggg gtcaggttgt ccggaatgtc tccggcgccg tgcgttgagc
     3241 tgattatcag ccagatcccg gaagttgaca gatcctctaa taacggaccg tgcaccgttt
     3301 cggttgaaaa accggcagct tccagctttt ccgccagatg ttccgcgacg tattcggcgc
     3361 cgcccagggt gctgccgctg ataagagtaa tgtctgccat tgatcgctcg ctcaggtaaa
     3421 gaggctgcat tgtactctgt gaacgagctg ggatctacct gtggaaaaat gtgggattaa
     3481 aaaagccgat catggcttga tggtgcgcat gatcgggttc tgcaagacga tcagtgtctc
     3541 agtggactga atttcatcaa ttgtttggat cttgttgata agtacgtgct gaagcgcgtc
     3601 aattgatttg cacatcactt ttataaagat gctgtagtga ccggtggtgt aatacgcttc
     3661 cgtcacctca tccaggcttt ccagccgggc cagtgcggag ggatagtctt tggcgctttt
     3721 gaggatgatg ccaataaagc agcctacatc gtagcccagt tgtttagggc tgacgtcaat
     3781 ccgtgcgccc gtaatgatcc cggcctgctt cattttctcg acgcgaacat gaatggttcc
     3841 agggctaacg ccaaattgtt tggccagttc ggcgtaggcg gtgcgggcat tttccattaa
     3901 ggcgtcaagt atgccgcggt ccagattgtc gatctgataa ttttccatcg ctttttctta
     3961 tgcagattaa tgattatctc tattttagcc attattttta acgaatcaaa atcgaagtta
     4021 gctttttatc tgttgattat tgaatagtgc tctcgttttg ttgcttaatc ataggcaaca
     4081 ggacgcagga gtaaaaaaat gaaaaccgct tacattgcca aacaacgtca aattagcttc
     4141 gtgaaatcac atttctctcg ccagctagag gagcgtctgg gtctgattga ggtccaggcg
     4201 ccgatcctga gtcgcgtagg ggatggtacg caggataatt tgtccggctg tgaaaaagcg
     4261 gtgcaggtaa aagtgaaagc gttgcctgac gcccagttcg aagtggtgca ttcactggcg
     4321 aagtggaaac gtcaaaccct ggggcaacat gacttcagcg cgggcgaagg gctgtacacg
     4381 cacatgaaag cccttcgccc cgatgaagac cgactctctc cgctccactc ggtctatgtg
     4441 gatcagtggg actgggagcg tgtcatgggc gatggcgagc gccaattttc caccctgaaa
     4501 agcacagtag aggctatatg ggcaggcatt aaggcgacgg aagcggaagt gcataaacag
     4561 tttggtctgg cgccgttcct gccggatcag atccattttg ttcacagtca ggaactgctg
     4621 gcgcgtttcc cggatctgga tgcgaaaggg cgcgaacgcg cgatcgccaa agaacttggc
     4681 gccgttttcc tggtggggat cggcggtaaa ctgagcgatg gccgccgcca tgatgtacgc
     4741 gcgccggatt atgatgactg gagctccgca tctgagctgg gctacgctgg tctgaacggc
     4801 gatatcctag tgtggaaccc ggtgctggaa gatgcgtttg agctttcctc tatgggtatc
     4861 cgcgtagatg ccgatacgct gatgcgtcag ctggcgttga ccggtgatga agatcgcctg
     4921 caactggagt ggcatcaggc gctgctgcgc ggcgaaatgc cgcagaccat cggcggcggg
     4981 attgggcagt cgcgtctgac gatgttgctg ctgcaattgc cgcatattgg tcaggtgcag
     5041 tgcggcgtat ggcccgcgca ggttcgcgaa agcattcctg ctattttata agccgttagc
     5101 gtcgccagcg tctcagcagg cggcttcgca tcccggtgtc aaagcgccag atatgatcga
     5161 aaatgcgcat gatgccgggt ttgccgtgcg ccgacatcgc caccgcatgg aatcgatgct
     5221 ggtgaagacg ctgcaactct cccactttgc tcaccacgtc atccggcaag cgctgggcga
     5281 taaaatccga aatgaccacc gcatcggcat caaaccattc ccgtccctgc attctttcaa
     5341 taatggcgcg aaaacagctg gcgatatccg tgccgccgcg aaaacgttga cttaaaaagc
     5401 ggatggcctg ctcaatactt tccgggccgg agagttcata acgcacaacg tcagtggaaa
     5461 acagcataat aaagcagcgg cggttatccg ccagcgcaac gcgcatcaac gccaggcaga
     5521 acgcttttgc gcactgctcg ttaaatcctc ccatcgagcc tgaagtatcg acgcagacaa
     5581 taaacggtcc gcgcggctgc tcgtcgacat cctggtgtac taccggccgt tcggtcactt
     5641 tctcacgcca cgcttcgcca tgcaggcgat aggtgaggag ctgtttttcc actaaccggc
     5701 ggtaaaattc atattccagc tcggtgatgc cgagcgtcgc cagctctggc ggcaacaggc
     5761 gcagaatatc atcgccttgc tgaataccgt caacctgctc cggcaccgtt gcgggttcgc
     5821 gtaccagtgt acgaaaggtt tccatcggcg cgtctttttt cggtaccgat ttggcttccc
     5881 gcgaacgtcc cagttgttcc gccagttgca ttagctccgg ctgggcggcg agaaattcgc
     5941 cgtattttac gatcagttga taatcaccac gtttaagctg gcccgcgctc atatcccaca
     6001 ggcggcctgc ggcattatca ttttccgcca acgtcggttc cagttgcccg ctcagcgtca
     6061 tccgttcctg tacgtcactc agcaactgct cgcgctcttc ttccagtagt tgctggttta
     6121 acgtggtggc ctgcacgacc agacttaacc gccagcgttg caaaaaaagc gtgtgtagcg
     6181 caggggtaaa ggtactgttg ctctccgtca actgcttcgc ctgcgcggca tacggtgaat
     6241 gcaggcgatg aagcaacgcc agtatttgcg gcagttgcac gatgaactgt ggggtagaga
     6301 gaagttggct ttgctgataa cacatgacct cttccgtgag ttccggcgga acgcgtgcgt
     6361 ctttaagacg gctgcgtagc gcttcccgcc agcgcgggag atcggcggtc acggcgtttt
     6421 ttaaacgtgg aaacttttca aagaaaatga ccagctgtgg ggaagccagt agcgcgagga
     6481 tcatctcttc gaccattccc tcttcgctga cggccagcat ggtatttagc gtatccagcg
     6541 tcagcattgt tgcgcctggc ggatctgttc tcctacatcc tgcaggctgg cctcaatgcg
     6601 ccctaaccag tcgctgtgaa taaacaggca atgttgctgc tcgctgaagc gggtatgctg
     6661 ctggcgccag tcgttttcta acgtttccag ctgctgtttg atctccgcag gcatactgtc
     6721 ttcagccgct cccggtaacg ccagacgggt accttgtaga ctgatgtcgc gcaccaccgg
     6781 atgttgagcg ttatcgactt ccatattcag cgtttgggca aagccgatcc cgttcagttt
     6841 gccgcggatc tcgccgcctt tggtcagcca aagttccagc gcgctgcggt caaaggtaat
     6901 atggatcact tccatatcat gcagttttag cggtttttgt agcaataacg tcaacgttga
     6961 cgcactggct tccggcggta aagtgtaatg cgggcgacgg ctgaacatac cgccttcttt
     7021 aatgacggtg aaggcggttt tatcgctttg ctgttgctgc aactggaggc ggcgctggac
     7081 gataccgccg aggcgagtca gcatggcctg ctgctgccag gcgtgtccgg tcatcaatat
     7141 ttccagttgc tgttgcatga gattcagact ctgcgcgtca taccacaagc aatcttttag
     7201 caggataagg tcaatcggcg caaccgcgtc gcgtccgcta aagaaggcgc tggcctgtaa
     7261 caggcggatg gctttcttcc agcgacggtc ggagacataa ggcgcattcg gcaaattatc
     7321 cagctgttgg cgcagagtaa atatcagctc aaagaccgga tcaggcagtg aaatcgcgcc
     7381 gatatctttt tgccactgtt gatattcttc gtcgctaacc tgtaacgagg cggggaccgg
     7441 gttatcactc tcatcctgct gactaaccag catggagcgg aaattggctt tatcctgaac
     7501 tttatccagc cacaggcgaa tcaacattcg gtcgtacaag gcttccaggc tgctgtccgc
     7561 ttcgggcagt tcgttagagg ccgccaccag tagccgcatc gggatttttt cctcaaacgc
     7621 gccgttgcgg aaatggcgtt cgttaatggc ggtcagcaat gtgttcagga tagcgggccc
     7681 ggctttccag atttcatcca gaaaaacgat ttcggcttcg ggaaggtagc cggtcgttaa
     7741 gcgttcatag cgaccttcat ctttcagcgc ctgaatagag agcgggccaa acacctcttc
     7801 cggcgtggaa aagcgtgtca tcagatattc aaaagcgcgg gcgcgctgga aagcaaactt
     7861 caggcggcgg gcaatcagac tcttggcgat accgggcggg cccaacaaaa agacgctctc
     7921 accgcttaac gccgccagta ggcacaggcg tatggcgtga ctacgttcat acagcccctt
     7981 ctcaagggcg ctgctcagac gggaaattct ttccgctaat aaatgtgggt gagccataat
     8041 aaagaggcgt cctttcgaca aatggatcat gctaattgcg agtatagacg tttcaccacc
     8101 ggggctgtaa tcttctgacg cgctgtttat ttttctttga gccaggttaa tctggcttca
     8161 tttaggggta cgattttatg attaatcgtg catactgtgc gcttttttgt gggccaaggg
     8221 actaagcaca catttcatat ctatacactc attcattcaa actacatcaa ggcggcaaag
     8281 gagtgaatcc cctggcactg acttaaacgt gtgactgggg taagcgaatg cagtcgacaa
     8341 ggaggtagcg tgaagggtga cgtgtataaa cgaaagatga gtctatgagc actgataata
     8401 agcaatcgtt gcctgcgatt accctcgcag ctattggggt tgtctacggt gatattggta
     8461 ccagcccgct ttatacgctt cgtgaatgtt tgtccggtca gtttggtttt ggcgttgaac
     8521 gagatgccgt gtttggtttt ctgtcgctga tcttctggct actcatcttt gtggtttcca
     8581 tcaaatatct caccttcgtg atgcgcgccg ataacgcggg tgaaggtgga attttgacgc
     8641 tgatgtcgct tgccgggcgt aatacctcgg cgcgcaccac atccatgtta gttatcatgg
     8701 gactgatagg cggcagcttt ttctatggcg aagtggtcat tacgccggcg atttcggtga
     8761 tgtcggcgat tgaaggcctg gagattgtcg cgccgcagct ggatacctgg attgtcccgc
     8821 tctccattat tgtgctgact ctgttgttta tgattcagaa gcacggtacg ggaatggtag
     8881 gaaaactctt tgcgccgatc atgctgacct ggtttttaat cctggcggta cttggcctac
     8941 gcagtattat cgccaatccc gaagtgttac atgcgctgaa tcctgtctgg gcggtacgtt
     9001 ttttccttga atataaaacc gtatcgttta ttgcgttggg cgcggtggtg ctgtcgatta
     9061 ccggcgtaga ggcgttgtac gccgatatgg gacacttcgg taagttcccg attcgcctgg
     9121 cgtggtttac cgtggtattg ccgtcgttag tactgaacta ctttggtcag ggtgcattgc
     9181 tactaaagca tccggaagcg attaaaaacc ccttcttcct gttggcgccg gactgggcgt
     9241 taattccgct gctgattctg gccgcgctgg cgacggtgat cgcctcccag gcggtaattt
     9301 ccggcgtctt ttcgctgacg cgtcaggccg tgcgtcttgg ctatttgtcg ccaatgcgca
     9361 ttatccatac ctccgagatg gagtccggtc agatctacat ccctttcgtt aactggctgc
     9421 tttatttcgc ggtcgtggtt gttattgtta gctttgagca ctccagcaac ctggcggcgg
     9481 cctatggcat cgccgtgacc ggcacgatgg tgctgacgtc tattctttct acgaccgtgg
     9541 cgcgtaagaa ctggcactgg aacaaatatt ttgtcgcgct gatcctcatc gcattcctgt
     9601 gcgtggatat cccgctgttc tcggctaacc tcgacaaatt gttgtccggc ggttggctgc
     9661 cgctgagcct gggtctgatc atgttcacga tcatgaccac ctggaagagc gagcgtttcc
     9721 gtctgttgcg tcgtatgcat gaacacggta attcgctgga agcgatgatt gcttcactgg
     9781 agaagtcacc gccggttcgg gtgccgggta ctgccgtata catgtcgcgc gcgctcagtg
     9841 tgatcccttt tgctttattg cataacctga agcacaacaa agtgttgcat gagcgcgtaa
     9901 tcttactgac gttgcgtacg gaagatgcgc cttatgtgca taacgttcgc cgggtgcaga
     9961 ttgagcagtt gtctccgaca ttctggcgcg tggtggccag ctacggctgg cgcgaaacgc
    10021 taaacgttga agaggtgttc caccgctgcg gtctggaagg ccttagctgt cggatgatgg
    10081 aaacgtcgtt ctttatgtcg cacgagtcgt tgattgtcgg caaacgcccg tggtatttgc
    10141 gtctgcgcgg caagctgtat ttgttgttgc aacgcaacgc cctgcgcgcg ccggatcagt
    10201 tcgagatccc gcctaaccgc gtgattgagt taggtacgca ggtcgagatt taacctctca
    10261 tcaacatgcc gggggccgca ttggcttacc cggcctggcc aatccgtaga ttcccacaag
    10321 ataatcgcca ttgggcgatt atcttcacct gatttccgct agcgaaacgt ttcgacggcg
    10381 atcacaattc tgttacgtca tgatggtttt atgaacacat ccagggttac actgcggcca
    10441 gcgaaacgtt tcgctagtgg agcagaaaaa tgaagaaagg caccgtactc aactctgaaa
    10501 tctcgtcggt catttcccgt ctggggcata ctgatactct ggtggtctgt gatgcgggtt
    10561 tacccatccc gaatagcact gcgcgtatcg atatggcact aacccagggc gtaccttctt
    10621 ttatgcaggt ggtggatgtc gtgacctggg aaatgcaggt tgaggcggcg attcttgcaa
    10681 cggaaatcaa acaacagaat ccgcagctcc acgaaacgtt gctcactcac cttgagcaac
    10741 tgcagcaaca ccagggaaac accataaaaa ttagttatac gacacacgaa caattcaaaa
    10801 aattgactgc agacagtcaa gcagtgattc gcagcgggga gtgttccccg tatgcgaacg
    10861 tcattatttg cgctggcgtc actttctgag gccgctatgg acgcattact gcaactcaaa
    10921 gggatcgata aagcgttccc cggcgtgaag gctctctccg gcgccgcgtt aaacgtttat
    10981 cctggccgcg ttatggcgct ggtgggggaa aacggcgccg gaaaatccac catgatgaaa
    11041 gtattaaccg gcatctatac gcgagatgcg ggatcgttgt tatggctggg taaagagacc
    11101 acctttaatg ggcctaaatc gtctcaggaa gccgggatcg gcattattca tcaggaactg
    11161 aacctgattc cgcagttgac cattgcggaa aacatcttcc tgggccgtga gtttgtgaat
    11221 cgctttggta aaatcgactg gaaaaagatg tatgccgaag ccgaccacct cttagccaaa
    11281 ctcaatctgc gctttaagag cgataagctg gtgggcgaac tctctatcgg cgatcagcaa
    11341 atggtggaaa tcgccaaagt gctgagcttc gaatccaaag tcatcattat ggatgaaccg
    11401 accgatgcgc tgaccgacac tgaaaccgac tctctgttcc gcgttatccg cgaattaaaa
    11461 tcgcaggggc gcggcattgt ctatatctct caccgtatga aagagatttt cgaaatttgc
    11521 gatgacgtga cggtcttccg cgatgggcaa tttatcgccg agcgtgaagt ggccacgttg
    11581 accgaagatt ctcttatcga aatgatggtg ggacgtaagc tggaagatca gtacccgcat
    11641 ctggataacg cgccgggtga gattcgcctg aaggtcgata atctgtgcgg accgggcgtg
    11701 aacgatgtct cttttgtgct gcgaaaaggc gagattcttg gcatctccgg cctgatgggc
    11761 accggtcgca ctgagctgat gaaagtattg tacggcgcga tgccgcgaac cagcggttac
    11821 gtgacgctcg agggacacga agtggtgacg cgttctccgc aggacgggct ggccaatggc
    11881 atcgtttata tctctgaaga ccgtaagcgc gatggactgg tgctcggcat gtcagttaaa
    11941 gagaatatgt cgctgactgc gctggattat ttcagtcgcg ctggcggaag cctgaaacac
    12001 aaagatgagc agcaggcggt gggggatttt atccgtctgt tcaacgtcaa gacgccgtca
    12061 atggaacagg cgataggcct gctttctggc ggtaatcagc aaaaagtggc gattgcccgc
    12121 gggttgatga cgcgcccgaa agtgctcatt ctcgacgagc cgacccgcgg cgtggacgtc
    12181 ggcgccaaga aagagattta ccagcttatc aaccagttta aggccgacgg cctgagcatc
    12241 attctggtct catctgagat gccagaagta ttaggcatga gcgatcgcat catcgtcatg
    12301 catgaagggc atctcagcgg tgaatttact cgcgagcagg ccacccagga agtgttaatg
    12361 gctgccgcag tgggcaagct taatcgcgtg aatcaggagt aaaaaagatg acaacccagg
    12421 ctgtttctgg tcgccgttat ttcactaaag cgtggcttct tgagcagaag tcgctcattg
    12481 ccctgctggt gttgatcgcg attgtttcga cgttgagccc caactttttt accgttaata
    12541 atctgttcaa tattcttcaa cagacctccg tcaacgccat tatggcggtg gggatgacgt
    12601 tggtgattct gacatcgggg atcgatctgt ccgtcggttc cctgctggca ctcaccggtg
    12661 cggttgccgc ttcaatcgtc ggcgttgaag tgaatgcgct ggtcgcggtt gccgccgcgc
    12721 tggcgctggg cgctgcgatt ggcgccgtca ctggcgttat cgtcgcgaag ggccgcgtac
    12781 aggcgtttat cgctacgctg gtgatgatgc tgctactgcg tggcgtgacg atggtttaca
    12841 ccgacggtag cccggtcaac accggcttta ccgataacgc cgatctgttt ggctggttcg
    12901 gtatcggtcg tccgctgggc gttcctacgc cggtctggat catggctatc gtctttatcg
    12961 ccgcctggta tatgctgcat cacacccgtc tgggacgcta tatctacgcg ctgggcggta
    13021 acgaagcggc gacgcgtctg tctggcatta gcgtgagcaa agtgaaaatt atcgtctatt
    13081 cactttgcgg cctgacagca tcgctggcgg gcatcattga agtggcgcgc ctctcttccg
    13141 cgcagccgac ggcgggtacc ggctatgagc tggatgctat tgccgccgtg gtgctgggcg
    13201 gcaccagcct tgcaggtggt aaagggcgca ttgttgggac attgatcggc gcattgattc
    13261 tcggcttcct taataatggt ttgaatttgt taggtgtttc ctcctattac cagatgatcg
    13321 tcaaagcggt ggtgattttg ctggcggtac tggtagacaa caaaaagcag taacaacgac
    13381 tacaggacat ctgaaatatg aacatgaaaa aactggctac cctggtatct gctgttgcgc
    13441 tgagcgccac cgtgagcgcg aatgcaatgg cgaaagacac cattgcgctg gtgatctcta
    13501 ccctcaataa tcccttcttc gtgtcgttaa aagacggggc gcaaaaagag gcggataaac
    13561 tgggttataa cctggtggtg ctggactccc agaacaaccc tgccaaagag ctggcgaacg
    13621 tgcaggattt aaccgttcgc gggaccaaaa ttttgctgat caacccgact gactccgatg
    13681 cggtgggtaa cgcggtgaag atggcgaacc aggcgaagat tccggttatc acgcttgacc
    13741 gccaggcaac caaaggcgat gtcgtcagcc atatcgcgtc tgataacgtg ctgggcggta
    13801 agatcgctgg cgactatatc gcgaaaaaag ctggcgaagg cgccaaagtg attgagctgc
    13861 aaggcattgc cggaacatct gcggcgcgtg agcgtggcga aggtttccag caggcggtag
    13921 ccgcccacaa atttaatgtc ctggccagcc agcctgccga tttcgaccgt actaaaggtc
    13981 tgaacgtcat gcagaacctg ctgaccgcgc atccggatgt tcaggctgtc ttcgcccaga
    14041 acgatgaaat ggcgctgggc gcactgcgcg cgctgcaaac tgccggtaaa gcagatgtga
    14101 tggtggttgg atttgacggt acgccggatg gcgaaaaggc cgtaaaagat ggcaaactgg
    14161 cagcgactat cgctcagtta ccggatcaaa tcggcgccaa aggcgttgaa gtagcggata
    14221 aggtgctgaa aggcgaaaaa gttcaggcca aatatccggt tgacctgaaa ctggtcatca
    14281 agcagtaata aacgacacgg gtcaactatg gcctgatggc gacagaaata cgcgagcctc
    14341 cgctgaggtg aacgtaaaaa aagaaaagca gggcacgcgc caccctaacc ggtggcgcac
    14401 tttgacgtgg aaccccgaat atgaaaaccg caggtaatct catcgtcctt ggcagcatta
    14461 atgccgatca tatccttaat cttgagtcct tccctacccc gggtgaaacg gtaaccggta
    14521 gccattatca ggtcgcgttt ggcgggaaag gcgcgaatca ggcggttgct gcgggacgta
    14581 gcggggcaaa tattgcgttt atcgcctgca cgggcgatga cgatattggc gacagtattc
    14641 gtaaacaatt agtcagcgat cgtattgata tcgcgccagt tagcgtcatt aaaggcgagt
    14701 ctaccggggt agcgctgatt ttcgttaatg gcgaaggcga gaacgtcatc ggtattcatg
    14761 ccggagcgaa tgccgcgtta tcgccggcgt tggttgatgc gcaacgtgaa cgtatcgcgc
    14821 aggcggatgc gttactgatg cagctggaat cgccgctgga aagcgtactg gcggcggcga
    14881 aaatcgccca tcaacatcat actactgttg cgcttaaccc ggcacctgcc cgtgagttac
    14941 cggatgaact gctggcgctg gtggacatca tcacgccaaa tgaaacggaa gctgaaaagc
    15001 tgacgggcgt gcgtgtggaa aatgacgacg atgtcgcgaa agctgcgcag gttttacatg
    15061 ataaaggcat tcgaaccgta ttaattacct taggaagccg tggcgtctgg gccagcgtaa
    15121 acggcgaggg tcgccgcgtt cctggattta gcgttgaggc tgtcgatacc attgccgccg
    15181 gagatacgtt taacggcgcc tttatcaccg cgatactgga ggagacgccg ttgccggaag
    15241 cgattcgctt tgcccatgcc gccgccgcga ttgccgtaac gcgtaaaggc gcgcaacctt
    15301 ccgttccgtg gcgcgaagag atagaagcgt ttttacatca gcaggggtaa cgcttggcta
    15361 ctatgaaaga tgttgcccgc ctggcgggag tctctacatc gacggtctct cacgttatta
    15421 acaaagatcg ctttgtgagt gagacgatta ctgaaaaagt tgaagcggcg attaaatcac
    15481 ttaactatgc gccttccgcg ctggcgcgaa gcctcaagtt aaaccagacc cgcacgattg
    15541 gtatgctgat taccgccagt accaaccctt tttattccga actggtgcgc ggcgttgagc
    15601 gaagctgttt tgagcgcggt tatagtctgg tgctgtgtaa taccgaaggc gatgagcaac
    15661 ggatgaaccg caacctagag acgctgatgc aaaaacgggt agacggttta ctgctgctgt
    15721 gtactgaaac gcatcagcct tctcgtgaaa tcatggaacg ttatccgtct attcctaccg
    15781 tcatgatgga ctggtcgccg tttgatggtg agggcgatag cgatctcatt caggataatt
    15841 cgttgttagg cggcgatctt gcgacccaac accttatcga taaaggattt acccgaatag
    15901 cctgtattac cggcccgctg gacaaaacgc ctgcgcgttt gcggctggaa gggtatcggg
    15961 cggcgatgaa acgcgcaggg ctggctattc cgcaaggcta tgagatcacc ggcgattttg
    16021 aatttggcgg cggctttgac gccatgcagg cgttactcgc ccatcaacag cgaccgcaag
    16081 cggtttttac cggaaacgat gcgatggctg tcggcgccta tcaggcgcta tatcaggcgg
    16141 ggcttcgtat cccgcaagat atggcagtca ttggctatga tgatattgag ctagcgcgct
    16201 atatgacgcc gccgctgacg actatccatc agccgaaaga tgaattgggc gagcttgcta
    16261 ttgatgtgtt gattcatcgg atggcgcagc ccgccttgca acaacagcga cttcagctta
    16321 ctccggtttt gacggtgcgt gggtcggttt agatttatgc cgttctttaa tcagattgtt
    16381 gccgtctttg gctcttagca gcataaacat cagcgcggac acgatagtga tcgcccccat
    16441 cgtgataaag gtatagtgga actgttccac ggtactggtg cccgcaaaac cttcataaat
    16501 acgtaacacc gccgcgctga tcgccacgcc taaactgata gacaattgct gcgtaactgc
    16561 cagaacgctg ttgccgctgc tggcgttatc gtccgtcaga tccgcaagag taatcgtatt
    16621 cattgccgta aattgagtgg acatcgccat tccaagaatg aatagcggca gtacgagcat
    16681 ccagatcggc atagcgggag attgaaacga aaactgggca atcatcagac cgataaatac
    16741 cgtaatgccg accagcgtct tcctgtatcc caaacgtcgt aaaacctgcg ttacggtcga
    16801 tttcgcgata atagaaccca aagccgtcgg cgccatcatg cagccggcga tcagagccgg
    16861 gtagccaaaa ccaacctgta gcattaacgg catcaaaaaa ggtacgcagc ctgtccccag
    16921 acgcgtggcg aggttgccgg caatgccaac ggaaaatgtg cgtgtcttaa acagcgatag
    16981 tgatattaac ggtgtcggat gacggcgggc gtggcggata taggccaata gtagaacgat
    17041 actgcaaaaa ataatggcgg atgcgatcca tgtcgccaca atcttttcgc caaacagttc
    17101 cattccgctg gaaaataaaa ccagacttaa cccaaaaaga aagaagccgg tcatgtcaaa
    17161 cttgcgacgc ggcgtggtga agttgggcat atatttgcgg gcatacagaa tgcctgcaac
    17221 cccaatggga atattaatca ggaagatcca gtgccagctt gcctaggtca ccagtacgcc
    17281 gcctaatacc ggccccagaa tcggacctac cagccccggc atagtgacaa agttaagaac
    17341 gggcagcagc tcactacgcg gataggctcg caataacgcc agtcgcgcca ctggcatcat
    17401 catcgctccg ccgacgcctt gtacgacgcg aaaaataacc aattcagata gtgaactgga
    17461 gagcgcgcag gccagcgagc ctaacgtaaa cagacttacg gcaaccataa agacgcgacg
    17521 cgtaccgaag cggtcagcca gccagccgct taccggaatt aacatggcta ctgtcagggt
    17581 ataactgata atagcggact gcatggcgag tggtgaacag ttaagactat gcgcaatagc
    17641 cggtaaagcg gtattcaaaa tggtggcgtc tagcgcctgc ataaagaagg ccatcgccgc
    17701 gatccacggc aggccagcca tactgcgcgc ttttttgctg gtcattcaat atcctgttaa
    17761 ttatctggtc tctcattggg cgctattaac aacgcctgac aggcctggaa agcgcgttcg
    17821 ccgtcgccat cagcgatggc atcaacaatg gcctggtgca aatccagctt taccacctcg
    17881 ttataggtga ttgaggtaaa gtaagtgtga taaaccgaat gaaatagcgt agcaaaagag
    17941 attagaaagg gattggcgct catttcgtag atatgctcgt gccacgccat atccacttca
    18001 atccagcgtt cacgcttaaa atgctttttc agcgcgacca tctcttccat taaggcatta
    18061 agccgcgctt tctgctccgg tgtgccaaga gtcgccgcca gcaggcaagc ttgcggctcc
    18121 aggctaatac gcatcaccag aaaatgatct accacctgat gaaaattttc ttccgtcatc
    18181 caccaggtca gcagctcttg atccagaaag ttccagtttc cctgcggcat cacccgcgta
    18241 ccaatgcgcg gacggggtag caccatacct ttagccgtca acgttttcac cgcttcgcga
    18301 actgccgttc gacttacgcc gtactgctcg cccagttcta tttcgccggg aagaatcgta
    18361 ccgggggcgt agtcaccctt taatatccgc tgcgccagct tttcagccag aacataggat
    18421 agatttttct gtgcggctaa ttgttgtgcg cttaaaggca tgaatgttct tcctttctct
    18481 ttcgtttggt tattagtatg ccacctggaa gtgtgattgc agttgcaata acggcaattt
    18541 gcttatttta tggcacgtta agcccgctgt tgatgaaaaa agag
//
LOCUS       DAJVBX010000078        18247 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.078, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000078 DAJVBX010000000
VERSION     DAJVBX010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 18247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18247
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.078"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..398
                     /locus_tag="OPV72_002323"
     CDS             <1..398
                     /locus_tag="OPV72_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="YehR family lipoprotein"
                     /protein_id="HCR9914602.1"
                     /translation="GCGDKEESKTFNANLAGTEISITYTYKGDKIIKQTSESKISYAT
                     VGAKTKEDAAKILDPLSAKYKNIAGVEEKLTYEDTYAQENVSVDMEKVDFKALQQISG
                     TMVSGDTSKGISMKQTQTLLEAAGFKEAK"
     gene            570..1100
                     /locus_tag="OPV72_002324"
     CDS             570..1100
                     /locus_tag="OPV72_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YehR family lipoprotein"
                     /protein_id="HCR9914603.1"
                     /translation="MQVLRLMALPLFALSLSVSITGCDQKNDTLQGKQNNMTAFIKKI
                     AASKESEETQRYVGNLNGIEIKLTYYYKGDIVLRQISEHKLLYKTLKANNKEEAQKML
                     SQVGEAYQGMPGLTERIDYYDSYATEYVDIDFTQAKISDLCKLPGSSIDNCSAYYLSM
                     IRSQKLLEESGYHRIN"
     gene            complement(1157..1624)
                     /locus_tag="OPV72_002325"
     CDS             complement(1157..1624)
                     /locus_tag="OPV72_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HCR9914604.1"
                     /translation="MLSNDILRSVRYILKANNTDLARILALGNVDATPEQIAIWLRKE
                     EEEGFQRCPDIVLSSFLNGLIYEKRGKDEAAPALTAERRINNNIVLKKLRIAFSLKTD
                     DILAILTGQLFRVSMPEITAMMRAPDHKNFRECGDQFMRYFLRGLAAREHAAK"
     gene            complement(1671..2390)
                     /gene="yehT"
                     /locus_tag="OPV72_002326"
     CDS             complement(1671..2390)
                     /gene="yehT"
                     /locus_tag="OPV72_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator BtsR"
                     /protein_id="HCR9914605.1"
                     /translation="MIKVLIVDDEPLARENLRILLQGQDDIEIVGECANAVEAIGAVH
                     KLRPDVLFLDIQMPRISGLEIVGMLDPEHRPYIVFLTAFDEYAIKAFEEHAFDYLLKP
                     IEEKRLEKTLHRLRQERSKQDVSLLPENQQALKFIPCTGHSRIYLLQMDDVAFVSSRM
                     SGVYVTSSEGKEGFTELTLRTLESRTPLLRCHRQFLVNMAHLQEIRLEDNGQAELILR
                     NGLTVPVSRRYLKSLKEAIGL"
     gene            complement(2387..4072)
                     /locus_tag="OPV72_002327"
     CDS             complement(2387..4072)
                     /locus_tag="OPV72_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCR9914606.1"
                     /translation="MYEFNLVLLLLQQMCVFLVIAWLMSKTRLFIPLMQVTVRLPHKL
                     LCYVTFSIFCIMGTYFGLHIEDSIANTRAIGAVMGGLLGGPVVGGLVGLTGGLHRYSM
                     GGMTALSCMISTIVEGLLGGLVHSVLIRRGRPDKVFSPLTAGAITCVAELVQMLIILL
                     IARPFDDALHLVSNIAAPMMVTNTVGAALFMRILLDKRAMFEKYTSAFSVTALKVAAS
                     TEGILRQGFNEVNSMKVAQVLYQELDIGAVAITDREKLLAFTGIGDDHHLPGKPISSG
                     YTLKAIETGEVVYADGNEVPYRCSLHPQCKLGSTLVIPLRGENQRVMGTIKLYEAKNR
                     LFSSINRTLGEGIAQLLSAQILAGQYERQKALLTQSEIKLLHAQVNPHFLFNALNTIK
                     AVIRRDSEQASQLVQYLSTFFRKNLKRPSEIVTLADEIEHVNAYLQIEKARFQSRLQV
                     QLDVPSTLSRQKLPAFTLQPIVENAIKHGTSQLLDTGNVAIRARREGQHLMLDIEDNA
                     GLYQPSAGSSGLGMSLVDKRLREHFGDDYGISVACEPDCFTRITLRLPLEEDA"
     gene            4295..5026
                     /gene="mlrA"
                     /locus_tag="OPV72_002328"
     CDS             4295..5026
                     /gene="mlrA"
                     /locus_tag="OPV72_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator MlrA"
                     /protein_id="HCR9914607.1"
                     /translation="MALYTIGEVALLCDINPVTLRAWQRRYGLLKPQRTDGGHRLFND
                     ADIDRIREIKRWIDNGVQVSKVKVLLSSDSSEQPNGWREQQEILLHYLQSSNLHSLRL
                     WVKERGQDYPAQTLTTNLFVPLRRRLQCQQPALQALLGILDGILINYIALCLASARKK
                     QGKDALVIGWNIHDTTRLWLEGWVASQQGWRIDVLAHSLSQFRPELFDGKTLLVWCGE
                     HQTLAQQQQLLAWRAQGHDIHPLGV"
     gene            5086..5193
                     /locus_tag="OPV72_002329"
     CDS             5086..5193
                     /locus_tag="OPV72_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YohO"
                     /protein_id="HCR9914608.1"
                     /translation="MRVAKIGVIALFLLMAIGGIGGVMLAGYSFILRAG"
     gene            complement(5174..5905)
                     /locus_tag="OPV72_002330"
     CDS             complement(5174..5905)
                     /locus_tag="OPV72_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR9914609.1"
                     /translation="MKRLCDPLLWLIVLFLLLLFGLPYSQPFFAALFPDLPRPVYQQE
                     SFAALALAHFWLVGISSLFAVVVGVGAGIAVTRESGKEFRPLVETIAAVGQTFPPVAV
                     LAIAVPVMGFGQQPAIIALILYGVLPILQATLAGLGAVPASVMSVASGMGMSRRQQLY
                     QVELPLAAPVILAGIRTSVIINIGTATIASTVGASTLGTPIIIGLSGFNTAYVIQGAL
                     LVALAAIIIDRLFERLTRALTRHAK"
     gene            complement(5889..6836)
                     /locus_tag="OPV72_002331"
     CDS             complement(5889..6836)
                     /locus_tag="OPV72_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR9914610.1"
                     /translation="MIEFNHVSKTFGDQQAVSDLNLHFSEGSFSVLIGTSGSGKSTTL
                     KMINRLVEHDSGTIRFAGEEIRSLPVLELRRRMGYAIQSIGLFPHWTVAQNIATVPQL
                     QKWSRARINDRIDELMALLGLESALRDRYPHQLSGGQQQRVGVARALAADPQVLLMDE
                     PFGALDPVTRGALQQEMTRIHQLLGRTIVLVTHDIDEALRLADHLVLMDGGHVIQQGS
                     PLSMLTSPENDFVQAFFGRSELGVRLLSLRSVGDYVRRHEQLSGDALVEEMTLRDALS
                     MFVARRCDVLPVANQQGEPCGTLHFRDLLSETSPRETTV"
     gene            complement(6829..7998)
                     /locus_tag="OPV72_002332"
     CDS             complement(6829..7998)
                     /locus_tag="OPV72_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR9914611.1"
                     /translation="MSDAAKKITVNRVLLLLVVLALLAVALPFINYAPNRLVSGEGRQ
                     LWEIWPATIWMLTGAGCALFTLCFVPGKRGSVLTLMMAQTLFIVMLWGVGRAATQLAQ
                     EGSPLARTSLGSGLWLGLGLMLLACSDAIRRITVGPLWRWLLHAQIVIVPLALLFSGT
                     FDNLSLLKEYTNRQDVFDAALVQHLMLLAGTVLPALAIGLPLGVWCYFSASRQGPVFT
                     VLNVIQTIPSVALFGLLIAPLAGLVKQFPWLAEFGVAGTGMTPALIALVLYALLPLVR
                     GVVAGLNQVPRDVLESARAMGMSSGQRFRHVQLPLALPVFLRSLRVVMVQTVGMAVAA
                     ALIGAGGFGALVFQGLLSSAIDLVLLGVIPVIALAVVIDALFDLWIAFLKGATDD"
     gene            complement(8002..8919)
                     /locus_tag="OPV72_002333"
     CDS             complement(8002..8919)
                     /locus_tag="OPV72_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCR9914612.1"
                     /translation="MTISKLWVSSLALLATVSLPLQAASPVTVGSKIDTEGALLGNMI
                     LQVLESHGVKTVNKIQLGTTPVVRGAITAGELDIYPEYTGNGAFFFKDENDPAWKNAK
                     QGFEKVKKLDAEQNKLVWLTPAPANNTWTIAIRQDIAEKNKLSSLADLSRYLKEGGTF
                     KLAASAEFIERSDALPAFEKAYDFTLNQNQLLSLAGGDTAVTIKAAAQQTSGVNAAMA
                     YGTDGPVAALGLQTLSDPKGVQPIYAPAPVVRESVLQAYPQIADWLQPVFASLDEKTL
                     QQLNARIAVEGLDAKKVAADYLRQKGWVK"
     gene            complement(9101..11398)
                     /gene="bglX"
                     /locus_tag="OPV72_002334"
     CDS             complement(9101..11398)
                     /gene="bglX"
                     /locus_tag="OPV72_002334"
                     /EC_number="3.2.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucosidase BglX"
                     /protein_id="HCR9914613.1"
                     /translation="MKWLCSVGVAVSLAMQPALAENLFGNHPLTPEARDAFVTDLLKK
                     MTVDEKIGQLRLISVGPDNPKEAIREMIKDGQVGAIFNTVTRQDIRQMQDQVMALSRL
                     KIPLFFAYDVVHGQRTVFPISLGLASSFNLDAVRTVGRVSAYEAADDGLNMTWAPMVD
                     VSRDPRWGRASEGFGEDTYLTSIMGETMVKAMQGKSPADRYSVMTSVKHFAAYGAVEG
                     GKEYNTVDMSSQRLFNDYMPPYKAGLDAGSGAVMVALNSLNGTPATSDSWLLKDVLRD
                     EWGFKGITVSDHGAIKELIKHGTAADPEDAVRVALKAGVDMSMADEYYSKYLPGLIKS
                     GKVTMAELDDATRHVLNVKYDMGLFNDPYSHLGPKESDPVDTNAESRLHRKEAREVAR
                     ESVVLLKNRLETLPLKKSGTIAVVGPLADSQRDVMGSWSAAGVANQSVTVLAGIQNAV
                     GDGAKILYAKGANITNDKDIVDFLNLYEEAVKIDPRSPQAMIDEAVQAAKQADVVVAV
                     VGESQGMAHEASSRTNITIPQSQRDLITALKATGKPLVLVLMNGRPLALVKEDQQADA
                     ILETWFAGTEGGNAIADVLFGDYNPSGKLPISFPRSVGQIPVYYSHLNTGRPYNPEKP
                     NKYTSRYFDEANGPLYPFGYGLSYTTFTVSDVTLSSPTMQRDGKVTASVEVTNTGKRE
                     GETVIQMYLQDVTASMSRPVKQLKGFEKITLKPGERKTVSFPIDIEALKFWNQQMKYD
                     AEPGKFNVFIGVDSARVKQGSFELL"
     gene            11665..13395
                     /gene="dld"
                     /locus_tag="OPV72_002335"
     CDS             11665..13395
                     /gene="dld"
                     /locus_tag="OPV72_002335"
                     /EC_number="1.1.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase"
                     /protein_id="HCR9914614.1"
                     /translation="MSSITMTDNKTFLNELARLVGHSHLLTDPAKTARYRKGFRSGQG
                     DALAVVFPGSLLELWRVLNACVNADKIILMQAANTGLTEGSTPNGNDYDRDIVIISTQ
                     RLDKLHLLDNGQQVLAWPGTTLYALEKALKPLGREPHSVIGSSCIGASVIGGICNNSG
                     GSLVQRGPAYTEMSLFARIDEQGKLQLVNHLGIDLGHTPEQILSKLDDERIKDEDVRH
                     DGRHAHDHDYVTRVRDINADTPARYNADPDRLFESSGCAGKLAVFAVRLDTFAAEKNQ
                     QVFYIGTNQPAVLTEIRRHILANFDNLPVAGEYMHRDIYDIAEQYGKDTFLMIDKLGT
                     DKMPFFFTLKGRTDAMLEKVKFFRPHFTDRAMQKFGHLFPSHLPPRMKNWRDKYEHHL
                     LLKMAGDGVAEAQRWLNEFFKSAEGGFFTCTPEEGSKAFLHRFAAAGAAIRYQAVHAD
                     EVEDILALDIALRRNDTDWFEHLPPEIDSQLVHKLYYGHFMCHVFHQDYIVKKGVDVH
                     ALKAQMLELLQARGAQYPAEHNVGHLYKAPETLTRFYRQNDPTNSMNPGIGKTSKRKF
                     WQENTPDETH"
     gene            complement(13454..14362)
                     /gene="pbpG"
                     /locus_tag="OPV72_002336"
     CDS             complement(13454..14362)
                     /gene="pbpG"
                     /locus_tag="OPV72_002336"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416638.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine endopeptidase"
                     /protein_id="HCR9914615.1"
                     /translation="MLAVPFAPQAVAKTAATTAASQPEIASGSAMIVDLNTNKVIYSN
                     HPDLVRPIASITKLMTAMVVLDARLPLDEILKVDISQTPEMKGVYSRVRLNSEISRKN
                     MLLLALMSSENRAAASLAHYYPGGYNAFIKAMNAKAKALGMTHTRFVEPTGLSIHNVS
                     TARDLTKLLIATKQYPLIGQLSTTREDMATFSHPAYTLPFRNTNHLVYRDNWNIQLTK
                     TGFTNAAGHCLVMRTVINNKPVALVVMDAFGKYTHFADASRLRTWIETGKVMPVPAAA
                     LSYKKQKAAQMAAASASAGAQTAQND"
     gene            complement(14567..15154)
                     /locus_tag="OPV72_002337"
     CDS             complement(14567..15154)
                     /locus_tag="OPV72_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014170891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIP1 family protein"
                     /protein_id="HCR9914616.1"
                     /translation="MNHVWGLFSHPDREMQVIKSENETVSHHYTHHVLLMAAIPVVCA
                     FIGTTQIGWNFGDGNVLQLSLFTAFALAVLFYGVMLAGVAVMGRVIWWMARNYPQRPS
                     LARCMVFAGYVATPLFLSGLVALYPLVWLCALVGAVALFYTGYLLYLGIPTFLNINRE
                     EGLSFSSSTLAIGVLVLEVLLAITVILWGYGYRLF"
     gene            15313..15882
                     /locus_tag="OPV72_002338"
     CDS             15313..15882
                     /locus_tag="OPV72_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001669449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HCR9914617.1"
                     /translation="MDINTLITHYGYAALVIGSMAEGETVTLLGGVAAHQGLLKFPLV
                     AAAVALGGMMGDQLLYLLGRCYGGKILRRFPRYHTKIRRAQKMIQRHPYLFVIGTRFM
                     YGFRVVGPLLIGASRLPPKIFLPLNIVGALIWALLFTTLGYLGGEVIAPWLHDLDQHL
                     RHGVWLILAIVLVVGVRWWLKRRGKAEAR"
     gene            complement(15930..16691)
                     /locus_tag="OPV72_002339"
     CDS             complement(15930..16691)
                     /locus_tag="OPV72_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCR9914618.1"
                     /translation="MTKVAIVTASDSGIGKACALLLAQNGFDIGITWHSDERGAQETA
                     KKAAQFGVRAETIHLDLSQLPEGAQAIEHLIQRLGRVDVLVNNAGAMTKSAFIDMPFT
                     QWRQIFTVDVDGAFLCAQIAARHMIKQGEGGRIINITSVHEHTPLPQASAYTAAKHAL
                     GGLTKSMALELIEHHILVNAVAPGAIATPMNDMDDSDIEPGSEPSIPIARPGSTHEIA
                     SLVAWLCSEGASYTTGQSLIVDGGFMLVNPQFNAK"
     gene            complement(16757..18193)
                     /gene="mdtQ"
                     /locus_tag="OPV72_002340"
     CDS             complement(16757..18193)
                     /gene="mdtQ"
                     /locus_tag="OPV72_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug resistance outer membrane protein
                     MdtQ"
                     /protein_id="HCR9914619.1"
                     /translation="MNRNSFLAATASLPLFILLAGCAPMHDTRQSLTQQTPSSHVDSS
                     LPAALKNGWPDSQWWKAYHDAQLDALIDNAIQHSPDMQVAEQRIQLAEAQAKAVEAQD
                     GPQLDFSADIERQRMSAEGLMGPFAITDPAAGTTGPWYTNGTFGLTAGWDLDLWGKNR
                     AEVTARIGAVKAREAEQEQTRQLLASGVARLYWEWQTQAALKNVLMQIEHEQQNVVAV
                     NRELYQHGITSSVEGVETDIDASKTQQQLNDVNGKMKVIEARLSALTNTQSAALKLRQ
                     VSLPAVESQLPSQLGYSLLARRADLQAAHWYIESSLSSIDAAKAAFYPDINLMAFLQQ
                     DALHLSDLFRHSAQQYGITGGLTLPIFDSGRLNANLDIAKAQSNLSIANYNKAVVDAV
                     NDVARAASQVETLAQKNQHQQQIEHDAQRVVGLAQARFNAGIIAGSRVSEAKIPALRE
                     QCNGLLLQGQWLDASIQLTSALGGGYHS"
BASE COUNT         4372 a         5177 c         4656 g         4042 t
ORIGIN      
        1 ctggctgtgg cgataaagaa gaatcaaaga cctttaacgc aaacctggcg gggacagaaa
       61 tttcaattac ttacacctat aaaggtgaca aaatcattaa gcagacgtct gaaagtaaaa
      121 tcagctatgc cactgtaggc gctaaaacga aagaagatgc cgccaaaatt ctcgatccgc
      181 tgagcgcgaa atataaaaat atcgccggag tggaagaaaa attaacctat gaagatacct
      241 atgcccagga aaacgtctct gtggatatgg aaaaagtgga ctttaaagcg ttacagcaaa
      301 tctcagggac gatggtgtcc ggcgatacca gcaaaggtat cagcatgaaa caaacccaga
      361 cgctgctgga agctgctggt tttaaagaag cgaaataact ggcaggcata atgtattgca
      421 tcgactggta aagtcgctca gggcgctgct tcggcagcgt cttttcttta tgaattccga
      481 aaaaagacag cctcgctgta agtcccctcg ccaaagccta taatccctga attcctggcc
      541 acaccaatac ttaacgacaa ggaattgtta tgcaggttct acgtcttatg gcactgccac
      601 tattcgcgct ctctctatcg gttagcataa ctggctgcga tcagaaaaac gatactctcc
      661 agggaaagca aaataacatg acagcgttta tcaagaagat agccgctagc aaagagtcag
      721 aggaaacaca acgctatgta ggtaatctca acggtattga aatcaagtta acctattact
      781 acaaagggga tatcgtttta cgtcaaatat ctgaacataa actactttat aagaccctga
      841 aagccaataa taaagaagaa gcacaaaaaa tgctgagtca agtcggcgaa gcttatcagg
      901 gtatgccggg tttgactgaa cgaatcgact attatgatag ctatgctacg gaatatgtgg
      961 atattgattt tacccaggca aaaataagcg acctctgtaa attgccagga tcatcaattg
     1021 acaactgttc cgcgtactat ctgtcaatga ttcgctcgca gaaactgttg gaagagagcg
     1081 ggtatcatag aatcaattag tataataatg cgttttcccg gtcagacagg acgctgccgg
     1141 gaacaatacc gcagaattac ttcgccgcgt gttcacgggc cgccagaccg cgcagaaaat
     1201 aacgcataaa ctgatcgccg cattcgcgga agttcttatg gtccggcgcg cgcatcatcg
     1261 cggtgatctc tggcattgag acacgaaaca actgaccggt aagtatcgcc aggatatcat
     1321 ctgtttttag cgaaaaggca atacgcagct ttttcagcac aatattgttg ttgatacgac
     1381 gttccgccgt caatgcaggc gccgcctcat ctttgccgcg tttttcataa atgaggccat
     1441 tgagaaatga ggacaacacg atatccgggc aacgctgaaa cccctcttcc tcttctttgc
     1501 gcaaccagat tgctatctgc tccggcgtag catcaacgtt acccagcgcc aggatacgcg
     1561 ccagatcggt attattagct tttaaaatgt agcgcacgct acgcagaata tcgttactca
     1621 gcatgaggcc ttcggtcgtt tctatggcaa aacgatattc taacagtctt ttacaggcca
     1681 atcgcctctt ttaaactttt cagatagcga cggcttaccg gcaccgtcag gccgttgcgt
     1741 aaaatcagct ctgcctgccc attatcctcc agccgaattt cctgcaaatg ggccatattc
     1801 accagaaact gacgatgaca acgcagtagc ggcgtccggc tttccagcgt gcgcagcgtc
     1861 agctcggtaa acccctcttt cccttcactg ctggtcacat aaacgccgct catacggcta
     1921 ctgacaaagg cgacatcatc catttgcaac aaatagatcc ggctgtgtcc ggtacaggga
     1981 atgaatttaa gcgcctgctg gttttccggc aacaacgaaa catcctgttt actgcgctcc
     2041 tgacgcagac gatgtaacgt tttttccagc cgtttctcct ctatcggctt gagcagataa
     2101 tcaaaagcgt gttcttcaaa ggctttgatg gcgtattcgt caaacgcggt taaaaaaacg
     2161 atatacgggc ggtgttccgg atcaagcatt cctactatct ccagtccact gatacgcggc
     2221 atctgaatat ccagaaacag cacatcaggt cgcaacttat gtaccgcgcc aatcgcttct
     2281 accgcgttcg cgcactctcc cacaatctca atgtcatcct gcccctggag caaaatccgc
     2341 agattttccc gcgctaacgg ctcatcatcc acaatcagca ctttaatcat gcgtcctcct
     2401 ccagtggaag tcgtaatgta attcgggtaa aacagtccgg ctcgcaggcc acgctaatac
     2461 cataatcatc gccaaagtgt tcgcgcagac gtttatccac cagactcatc cccagcccgc
     2521 tactgccggc ggaaggctga tacagtcccg cattatcttc aatatctaac atcaaatgct
     2581 gcccttcgcg ccgggcgcga atagcgacgt tgccggtatc aagcagttgc gacgtgccat
     2641 gtttaatggc gttctcaaca atcggctgta atgtaaacgc aggcaatttc tgacgtgaaa
     2701 gcgtcgatgg aacatcaagc tgtacctgca gacgcgactg aaaacgcgct ttttcaattt
     2761 gcaggtaagc gttcacgtgt tcaatttcat ccgccagcgt gacgatttcc gacgggcgtt
     2821 ttaaattttt gcgaaaaaag gtcgacaagt actgcaccag ttggctggcc tgttcgctgt
     2881 cgcggcgaat caccgcttta atggtattga gcgcattaaa cagaaaatgc ggattcacct
     2941 gcgcgtgcaa cagcttgatc tctgactgcg tcagcaacgc cttctgccgt tcatactgcc
     3001 cggccaggat ctgcgcggat aaaagctgcg caataccctc ccccagagta cggttaattg
     3061 agctgaacag tcggtttttc gcttcgtaca atttaatggt gcccatgact cgctgatttt
     3121 cgccacgcag cgggatcacc agcgtcgagc cgagtttaca ctgcgggtgt agcgaacagc
     3181 gatacggcac ttcgttgcca tcggcataaa ccacctctcc ggtttcaatt gctttcagcg
     3241 tataacctga tgaaatgggt ttgcccggta gatggtgatc gtcgccaata ccagtaaaag
     3301 ccagcagttt ttcgcgatcg gtgatggcga cggcgccaat atccagctcc tgatataaca
     3361 cctgcgccac cttcatactg ttcacttcgt taaatccctg acgcagaatc ccctccgttg
     3421 acgcggcgac cttcagcgcg gtaacagaaa atgccgaagt atatttttcg aacatggcgc
     3481 gcttatcgag caaaatacgc ataaacagcg cggcgccaac ggtattcgtc accatcatcg
     3541 gcgcggcaat attactgacc agatgcaggg catcgtcaaa cggcctggct atcagtaaaa
     3601 tgatcagcat ctgcaccagt tcggcaacac acgtaattgc tcccgccgtc agcgggctaa
     3661 acactttgtc cgggcgtccg cgacgtatga gaacgctgtg taccaacccg cccagcagcc
     3721 cttcgacgat ggtggaaatc atacagctca gcgccgtcat gccgcccata gaataccgat
     3781 gtaacccacc ggtcagaccg accagcccgc cgacgaccgg cccgccgagt aggccgccca
     3841 tcaccgcgcc aatcgcgcgg gtattggcaa tcgaatcttc gatatgtagc ccaaaataag
     3901 tgcccataat gcagaagata gaaaacgtga cataacacag aagcttgtgc ggcagacgaa
     3961 ccgtgacctg cataagcggg atgaacaggc gcgttttact cattagccac gcaatgacca
     4021 gaaacacgca catctgctga agcagcagca acaccagatt aaactcgtac atacccgcaa
     4081 accacacttc aattaaaagc gcgtaacata cattgagtac gattaacttt ctttgaactg
     4141 ttgcataaaa atatgaattc gtgaatacga tcacttaaac gccgcgccgc aacccgctac
     4201 ttcgcgtttt aatgcataaa aaacaggcaa aacttcctgg ttcctaaaag agcgtctaaa
     4261 gttaaaccgg gacctcgcga gcaagggtga aacgatggcg ctttacacaa ttggtgaagt
     4321 ggctttgctt tgtgatatca atcctgtcac gttgcgcgcg tggcagagac gttatggact
     4381 tttaaaacca cagcgaacgg atggcggtca tcgtctgttt aacgatgccg atatcgacag
     4441 aatccgcgaa atcaagcgct ggatagataa cggcgtccag gtcagcaaag tcaaagtgct
     4501 gctcagtagc gacagtagcg aacaacctaa cggctggcgc gaacagcagg agatcctgct
     4561 gcactacctg caaagcagta atctgcacag tttacggtta tgggtcaaag aacgcggtca
     4621 ggattatcct gcccaaacat tgaccactaa cctgttcgtc ccactgcggc gacgattaca
     4681 gtgccaacaa cccgcccttc aggcgctgct cggcattctt gacggtatcc tgatcaacta
     4741 tattgcgctc tgcctggcgt ctgcgcgtaa gaaacaggga aaagatgcgt tggtgatcgg
     4801 ctggaatatc catgatacca cccgcctgtg gctggaaggt tgggtcgcca gccaacaggg
     4861 atggcgaatc gacgtgttgg cgcattcgct tagccagttc cgcccggaac tttttgacgg
     4921 caagacgtta ctggtatggt gcggagaaca ccagacgctg gcgcagcagc agcaactcct
     4981 ggcatggcgc gcccagggac acgacattca tccccttggc gtttaaacag cagctaacaa
     5041 attcgcttta atgtatactc cttttattaa cataaggagt acataatgcg cgtagcgaaa
     5101 atcggggtga tcgccctttt cctgctgatg gctattggcg gtatcggcgg cgtgatgctg
     5161 gcaggttaca gttttatttt gcgtgccggg taagcgcgcg cgtcagcctt tcaaacaggc
     5221 gatcgataat gatcgccgcc agcgccacca gcagcgcccc ctggataaca taggccgtat
     5281 taaagccgct aagcccgata atgatcggcg tgcctaacgt actggccccc accgttgaag
     5341 cgatggtcgc cgtaccaata ttgataatca ccgaggttcg gatgcccgcc agaatcaccg
     5401 gcgcggccag cggcagctca acctgataca actgttggcg acggctcatt cccataccgc
     5461 tggcaacgct catcacgctg gcaggcaccg cgcccagccc ggccagggtc gcctgcagga
     5521 tgggcaacac cccatacagg atcaaggcga taatggccgg ttgctgacca aaacccatga
     5581 cgggtaccgc gatcgccagt accgcgaccg gcggaaaggt ctgcccgacg gcggcgatag
     5641 tctccactag gggacgaaac tctttcccac tttctcgcgt gaccgcaatc cctgcgccga
     5701 cgcccaccac gacggcaaac aaacttgaga tgcccaccaa ccagaaatgg gcgagcgcga
     5761 gggcggcaaa actctcctgt tggtagaccg ggcgcggtaa atcgggaaac agcgcggcga
     5821 agaacggctg gctataaggc aatccaaaca gcagaagcaa gaacagaaca ataagccaga
     5881 gaagcggatc acacagtcgt ttcacggggg gacgtctccg aaagcagatc gcggaaatgg
     5941 agcgtaccgc agggctcgcc ctgctgattc gccaccggca ggacgtcgca ccgacgggcg
     6001 acaaacatcg atagcgcatc gcgtagcgtc atctcttcca ccagcgcgtc gccgctgagc
     6061 tgttcatgcc gacgtacata atcgcctacg ctacgtaacg aaagcagcct tacgcccagc
     6121 tcgctgcggc caaaaaatgc ctgcacgaaa tcattttccg gcgaggtcag catagaaagt
     6181 ggcgatccct gttggataac gtggcccccg tccatcagca ccagatggtc ggcgaggcgt
     6241 agcgcctcgt cgatgtcgtg cgtcaccagt acgatggtgc gccccagtag ctgatgaatg
     6301 cgggtcatct cctgctgcaa tgcgccgcgc gttaccggat caagcgcgcc gaaaggctcg
     6361 tccatcagca atacctgcgg atcggcagcc agcgcccgcg caacgccgac ccgctgctgt
     6421 tgcccgccgg aaagctgatg cggatagcga tcgcgcagcg cgctttccag acccaataat
     6481 gccatcagtt catcaatacg atcgttaatc cgcgcacgcg accacttttg tagttgcggt
     6541 acggtggcga tattttgcgc caccgtccag tggggaaaaa ggccgataga ctgaatggca
     6601 tagcccatgc gacggcgcag ttcaagcacc ggcaggctgc ggatctcttc accggcaaaa
     6661 cggatcgttc cgctatcatg ctctaccagc cggttaatca tcttcagagt ggtcgatttt
     6721 cccgaaccgg aggtgccaat taacaccgaa aagctgcctt cgctaaagtg caaattgagg
     6781 tcgctaacag cctgttgatc gccgaaggtt ttactgacat ggttaaattc aatcatcggt
     6841 tgctcccttc aaaaacgcga tccataaatc aaacagcgcg tcgatcacta ccgccagcgc
     6901 aatcaccgga atgacgccca acaggactaa atcaatggcg ctgctcaata gcccctgaaa
     6961 caccagcgcg ccgaaacctc ccgcgccaat cagcgcggcg gcgacggcca ttcccactgt
     7021 ctggaccatt actacccgca ggctacgtaa aaagaccggc agcgccagcg gcagttgcac
     7081 atgcctgaag cgctggccgc tactcattcc cattgctctt gcgctctcca gcacatcgcg
     7141 tggcacctga ttgagcccgg cgaccacgcc gcgcaccagc ggcaataacg catagagcac
     7201 cagcgctatc agcgcaggcg tcatgccggt tcccgcgacg ccgaattcgg caagccacgg
     7261 aaactgtttc accagcccgg ccaacggcgc gatcagcagg ccaaacagcg cgacggaagg
     7321 aatagtctgg atcacattca gtacggtaaa caccggcccc tggcgtgagg cggaaaaata
     7381 acaccagacg cccaacggta gtccgatcgc cagcgccggc agcaccgtgc ccgccagtaa
     7441 cattaaatgt tgcaccagcg cggcatcgaa aacatcctgg cggttggtat actctttcag
     7501 aagcgagagg ttgtcgaacg tgcctgaaaa cagcagcgcc agcgggacaa tgacaatttg
     7561 cgcgtgcagc aaccagcgcc acagcggccc aacggtaata cggcggatcg catcgctaca
     7621 ggccagcagc atcagaccga ggcccagcca caatccactt cccagactgg tacgcgccag
     7681 cggactgccc tcctgcgcca actgggtcgc cgccctgccg actccccaca gcatgacaat
     7741 aaaaagcgtc tgcgccatca tcagcgtcag tacgctaccg cgtttaccgg gcacaaagca
     7801 cagcgtaaac agcgcgcatc ccgcgccagt cagcatccag atggtcgccg gccagatctc
     7861 ccataactgg cgcccctcgc cgctcaccag acgattcggg gcgtaattaa tgaaaggcag
     7921 cgcgacagca agcagggcca gaacaaccaa cagcaacagc acacgattaa ccgtaatttt
     7981 tttggcagcg tcactcacag attacttcac ccaccctttt tgtcggaggt aatctgcggc
     8041 gacttttttc gcatccagcc cttctacggc gattctggcg ttcaactgtt gcagcgtttt
     8101 ctcatcaagg ctggcgaaaa cgggctgcag ccaatcggct atctgcggat aggcctgtaa
     8161 caccgattca cgcactaccg gcgcgggggc atagataggc tggacgcctt tcgggtcgct
     8221 cagggtttgc agacccagcg cggcgaccgg gccgtcggtg ccatacgcca tcgcggcgtt
     8281 aacaccggat gtttgttgcg cggcggcttt gatcgtgacc gccgtatcgc cgcccgccag
     8341 cgacaagagc tggttctgat tcaaggtaaa atcataggct ttttcaaatg ccggcagcgc
     8401 atccgaccgt tcgataaatt ccgcagacgc cgccagttta aaagtgccgc cctctttcag
     8461 ataacggctg agatcggcaa gcgaggagag tttatttttt tccgcgatgt cctgacgtat
     8521 cgcgatggtc caggtgttgt tggccggcgc aggcgtcaac cagaccagct tattctgctc
     8581 cgcatccagt tttttgactt tctcaaagcc ttgctttgca tttttccatg ccggatcgtt
     8641 ttcatcttta aaaaagaacg ccccgttacc ggtgtattcc ggatagatat ccagctctcc
     8701 ggcggtaatc gcgccacgaa cgactggcgt cgtcccgagc tgaattttat tgaccgtttt
     8761 aacgccgtgg ctttccagta cctgcaaaat catgttgccg agcagtgcgc cttcggtatc
     8821 aatctttgac ccgaccgtca cgggcgatgc cgcctgtaga ggtaaactca ccgtcgccag
     8881 caacgccagc gaacttaccc atagctttga gatcgtcatg atgctttcct catcctttta
     8941 cggccttttt cagaaacttg agaaaaaagc atagttgaaa agtctgcgtt taacctggga
     9001 ttttccggca gtttaagtga cgtggcaggc aataaaaggg ggggacagaa aaagtcattg
     9061 ccagacaggg cgctgctatc gcgccctgtt gacggcaggc ttacagtagc tcgaacgatc
     9121 cttgtttaac gcgagcggaa tccacgccga taaagacgtt gaacttgccg ggttccgcgt
     9181 catatttcat ctgctgattc cagaacttca acgcctcgat atcaatcggg aaactcacgg
     9241 ttttacgttc gccgggcttg agggtgattt tttcaaagcc ttttaattgc ttcaccgggc
     9301 ggctcatcga cgccgtgaca tcctgtaagt acatctggat gaccgtttcc ccttcgcgtt
     9361 taccggtatt cgtgacctct acgctggccg tgactttgcc gtcgcgttgc attgtcggtg
     9421 aggagagcgt gacgtcagac accgtaaatg tggtgtagct cagaccgtaa ccaaacggat
     9481 agagcgggcc attcgcttcg tcaaaatagc gtgaggtgta tttgtttggc ttttcaggat
     9541 tatacgggcg tcccgtattg agatggctat aatagaccgg aatttgtccc accgaacgcg
     9601 ggaaggagat cggcagtttg cctgacgggt tgtaatcgcc aaacagcaca tcggcaatgg
     9661 cgttgccgcc ttccgtcccg gcaaaccagg tctccagaat cgcatcggct tgttgatctt
     9721 cttttaccag cgccagcggt ctgccgttca ttaataccag taccagcggc ttaccggtgg
     9781 ctttcagagc ggtgattaag tcgcgctgac tctgcggaat ggtgatattg gtacgactgg
     9841 aggcttcatg cgccatcccc tgcgactcgc ctaccactgc gaccactaca tcggcctgtt
     9901 tcgccgcctg caccgcctca tcaatcatcg cctgcggtga gcgcggatcg attttcaccg
     9961 cctcttcata caggtttaag aaatcgacga tatctttatc gttagtgata ttcgcccctt
    10021 tggcatagag gatcttcgcc ccgtcaccga cggcattttg aatacccgcc agcaccgtca
    10081 ctgactgatt cgcgacccca gcagcagacc agcttcccat tacatcacgt tgactgtcgg
    10141 ccagcggccc aacaacggca atggtgcccg attttttcag cggcagcgtt tccagccggt
    10201 ttttcagcag aaccacactt tcccgcgcca cttcccgtgc ctctttacga tgcaggcggc
    10261 tttcggcatt ggtgtccacc gggtcgctct ctttcggtcc cagatggcta taggggtcgt
    10321 taaacaatcc catgtcatat tttacgttga gcacatggcg cgtcgcgtcg tccagttccg
    10381 ccatcgtcac tttgcccgac ttaatcagac ccggcagata tttgctgtaa tactcatccg
    10441 ccatgctcat atccacccct gcctttagcg ccacgcgcac cgcatcttcc gggtcggccg
    10501 cggtaccgtg tttaatcagt tctttaatag cgccgtggtc ggaaacggta attcccttaa
    10561 agccccactc atcgcgcagg acatctttca atagccagga atctgacgtc gcaggcgtgc
    10621 cgttcagcga gttcagcgcc accatcaccg cgccgctccc cgcatccagc cccgctttgt
    10681 acggcggcat gtagtcatta aacagacgct gggaactcat atccacggtg ttgtattctt
    10741 taccgccttc aacggcgcca taggcggcaa aatgtttcac gctggtcatc accgaatagc
    10801 ggtccgccgg gcttttgccc tgcatcgctt tcaccatggt ttcgcccatg atggaggtta
    10861 aatatgtatc ttcgccaaag ccttcggagg cgcgtcccca acgcggatcg cgggagacat
    10921 ccaccatcgg cgcccaagtc atattcagac cgtcgtccgc cgcttcatac gccgatacgc
    10981 gtcctacggt tcttaccgca tccagattaa aagaagaagc cagaccgagg cttatcggga
    11041 agacggttcg ctggccgtgt accacgtcat aagcaaaaaa gagaggaatt ttcaggcggc
    11101 tcaatgccat cacctgatcc tgcatttgac ggatatcctg gcgggtgacg gtattgaaaa
    11161 tcgcccctac ctgcccgtct ttgatcatct cgcgaatcgc ttctttcggg ttatcagggc
    11221 cgacgctaat cagacgtaac tgaccaattt tttcatcgac agtcattttc ttgagtaaat
    11281 ccgtgacgaa cgcgtcgcgc gcttcgggcg tcagcgggtg attgccaaac aggttttccg
    11341 ccaatgctgg ctgcatcgcc agactcacag caacacctac tgaacataac catttcatgt
    11401 tgagtctctc tttatcttta tcccgacgag gcggtaaaaa cagaataaaa accgcagttt
    11461 gccataagcc taaacgcgag aggagaagaa agcgaaggtt attctcctaa ttttccgcac
    11521 agtcgaatac gcaaccgcca gcaaatggta tcaaggcggc aaatgaatac caccaacaca
    11581 gaaacaattt gaatgagaaa gcgtattgtc atacaaagcg ctatgcttaa cgctgatatt
    11641 ttgtcccacc acaaggagtg gagaatgtct tccataacaa tgactgataa taaaacgttc
    11701 ctgaatgagc tggcccgcct ggtaggccat tctcacctgc tgacagaccc cgccaaaacc
    11761 gcccgctatc gcaagggttt ccgttccggt cagggcgacg cgctggccgt tgttttcccg
    11821 ggttcattac tggaactgtg gcgtgtgctc aacgcctgcg ttaacgctga caaaattatt
    11881 ctgatgcagg ccgccaacac cggtctgacg gaaggctcca cgccgaacgg caacgactac
    11941 gatcgcgata ttgtgattat cagcacccag cggctggata agctgcactt actggataac
    12001 ggccaacagg ttctggcctg gcccggtacg acgctctatg cgctggaaaa agcgcttaaa
    12061 ccgctgggcc gtgaaccgca ctcggtgatt ggttcgtcgt gtatcggcgc gtcggtcatc
    12121 ggcggcatct gtaataactc cggcggctcg ctggtgcagc gcggcccggc ctataccgag
    12181 atgtcgctct ttgcccgtat tgacgagcaa ggcaaactgc aactggtcaa tcatctgggt
    12241 atcgatcttg ggcatacgcc ggagcagatc ctgagcaagc tggatgatga acggattaaa
    12301 gatgaggatg tgcgtcacga tggtcgtcat gcgcacgatc acgactacgt gacgcgggta
    12361 cgagatatca acgccgatac gcccgcccgc tataacgccg acccggaccg tttgtttgaa
    12421 tcttccggct gcgccggaaa actggcggtt tttgccgttc gccttgatac ctttgcagcg
    12481 gaaaaaaatc agcaggtttt ttatatcggc accaatcagc ccgcggtact gactgaaatc
    12541 cgtcggcata ttctggcgaa cttcgacaat ctgccagtgg cgggagaata tatgcatcgc
    12601 gatatctacg atattgcgga gcagtacggt aaagatacct ttctgatgat cgataaactc
    12661 ggcaccgaca agatgccatt ctttttcacg ctaaaaggcc gaaccgatgc gatgctggaa
    12721 aaagtaaaat ttttccgacc gcatttcacc gaccgcgcga tgcagaaatt cggccatctg
    12781 tttcccagcc atctgccgcc gcgaatgaaa aactggcgcg ataaatatga gcatcatctg
    12841 ctgttaaaaa tggcgggaga cggcgtcgca gaagcgcaac gctggctgaa tgaatttttt
    12901 aaatccgctg agggcggttt cttcacctgt acgccggaag aaggcagcaa agccttcctg
    12961 caccgcttcg ccgctgctgg cgcagcgatt cgttatcagg ccgtacacgc tgatgaagtg
    13021 gaagatattc tggcgctgga tatcgccctg cgccgcaacg ataccgactg gttcgagcat
    13081 ctgccgccgg aaatcgacag ccaactggta cataaactct attacggtca ctttatgtgc
    13141 cacgtttttc atcaggacta tatcgtgaag aaaggcgtcg acgtccatgc gctgaaagcg
    13201 caaatgctgg agctgttgca ggcgcgcggg gcacaatacc cggcggagca caacgttgga
    13261 catctgtata aagcgccgga aacgctgacg cgtttttatc ggcaaaatga cccaaccaac
    13321 agtatgaacc ccggtatcgg caaaacgagt aagcggaaat tctggcagga aaatacgccc
    13381 gacgaaacgc attaacacgg tgtggtttac cgtgaatgcc cggcggcgcg atgcctgccg
    13441 ggcctgcggc gacttaatcg ttctgtgcgg tttgcgctcc ggcgctggcg ctggctgccg
    13501 ccatttgcgc ggctttttgc tttttatagc tcagcgcggc agccggaacg ggcatgactt
    13561 taccggtttc aatccatgta cgcaggcgac tggcgtccgc aaagtgggta tatttgccga
    13621 acgcgtccat gaccaccagc gcgaccggtt tgttattgat cacggtacgc atcaccaggc
    13681 aatgccccgc cgcattggta aagccggttt tcgttaactg gatattccag ttatcacggt
    13741 agaccaaatg gttggtattg cgaaacggca gcgtatacgc cggatgcgag aatgtcgcca
    13801 tatcttcgcg cgtggtgctt agctggccaa tcagcgggta ttgcttcgtg gcaatcagca
    13861 attttgttaa atcccgcgcg gtcgagacgt tatgaatcga cagccccgtc ggctcaacaa
    13921 agcgggtatg cgtcatgccc agcgctttcg ccttcgcatt catcgcttta ataaatgcgt
    13981 tataaccgcc gggataatag tgcgccaggc ttgccgccgc acggttttcg gatgacatca
    14041 acgccagcag caacatattt ttgcggctaa tttcgctgtt caggcgcacg cgggagtaaa
    14101 cccctttcat ttccggcgtc tggctgatat cgaccttcag tatttcatcc agcggcaatc
    14161 gcgcgtcgag cacgaccatc gctgtcatta atttggttat cgaggcaatc ggacgcacca
    14221 gatccgggtg gttcgaatag atcactttat tggtgttgag atcaacaatc attgcgctac
    14281 cggaggcaat ctcaggttga gacgccgcgg ttgtcgctgc cgttttcgcc acagcctgcg
    14341 gggcaaaagg aacggccaac atcagagcaa ggctcaggaa tgaagctcag aatttcagca
    14401 tgatgagatt tctgataatg attcacgcgc gtcgtaacgc acaccgcctg agctaagatt
    14461 atactcaagc tagcagtggc atcatagcgg cacgccagcg ttgccgctac agaagaatcg
    14521 tcagcaaatg ctgcattgct ggcttttgcg ccagcccttt ttcgcatcag aacaggcggt
    14581 agccatatcc ccacaggatc acggtgatcg ccagcagcac ctccaggacc agtacgccga
    14641 tagcgagcgt cgaactggag aagcttaatc cctcctctct attaatgtta aggaaagtcg
    14701 gaatacccaa atacagcaaa tagccggtgt aaaaaagcgc gacagcgccg accaaagcgc
    14761 atagccatac caggggatag agcgccacca gaccacttaa aaacagcggc gtcgcgacat
    14821 agccggcaaa aaccatacag cgcgcaagcg atggccgttg cggatagttt cgcgccatcc
    14881 accagatgac gcgtcccatc accgcgacgc ccgccagcat cacgccgtag aacaagaccg
    14941 ccagcgcaaa agcggtaaac agcgagagtt gtaacacgtt gccgtcgcca aaattccagc
    15001 cgatttgcgt cgtgccgata aaggcgcaga cgacgggaat cgccgccatc agcaaaacat
    15061 ggtgcgtata gtgatgcgaa acggtttcgt tttcgctttt gatcacctgc atttcccgat
    15121 cgggatggga aaaaagcccc catacatggt tcatactgcc cccttctgct gcctcagatg
    15181 ccagtatgtt caagtataat tcagtttctg gttattttat gagcaatggc aaaatagtct
    15241 ccggcaaaac gtcggctttg ccgcgcacgc ctcttgccag ggtgtatgct taatgccgga
    15301 ggtggtttac gcatggatat caacacgctt attacgcatt atggctatgc ggcgctggtt
    15361 atcggcagta tggccgaagg tgaaaccgtt accctgttgg ggggcgtcgc ggcgcatcag
    15421 ggattactca agtttccgct ggtggcggcg gccgtcgcgc tgggagggat gatgggcgat
    15481 cagctacttt acctgttagg acgatgctat ggcgggaaga tcctgcgtcg tttcccgcgt
    15541 tatcatacga agattcgtcg cgcgcagaaa atgatccaac gccatccgta tctgtttgtg
    15601 atcggcacgc gttttatgta tggcttccgg gtggttggcc cgctgctgat tggcgccagc
    15661 cgcctgccgc ctaaaatttt tctgccgctg aatattgtag gcgcgctgat ctgggcgctg
    15721 ctgtttacca cgctgggata tcttggcggc gaggtgatcg cgccatggct gcacgacctc
    15781 gatcagcatc tcaggcacgg agtctggctg attctggcca tcgtcctggt ggtgggcgtg
    15841 cgctggtggc tgaaaagacg cggcaaagcg gaggcccgtt aaacccgatg gtatccggat
    15901 ggcataacgc cgccatccgg ccccggcgtt tattttgcgt tgaattgcgg attcaccagc
    15961 ataaatccgc cgtcgacaat cagcgactga ccggtggtat agcttgcgcc ttccgaacac
    16021 agccaggcga cgaggctggc tatttcatgc gtagaacccg gtcgggcgat agggatcgag
    16081 ggttccgatc ccggctcaat gtcgctgtca tccatatcat tcatcggcgt ggcgatagcg
    16141 cctggcgcga cggcgttgac caaaatatga tgctcaatca gttccagcgc catggattta
    16201 gtcaatcccc ccaacgcatg tttcgccgcg gtataggcgc tggcttgcgg aagcggcgta
    16261 tgctcatgga cggaggtgat gttgataatg cgccctccct ctccttgttt aatcatatgc
    16321 cgggcggcga tctgcgcgca gagaaacgcg ccatcgacat ccacggtaaa aatttgccgc
    16381 cactgcgtaa acggcatatc aataaacgcg gatttggtca tcgccccggc attattgacc
    16441 agcacgtcaa cgcgccccag gcgctggata agatgttcaa tggcctgcgc gccctcgggt
    16501 aactggctca ggtcaagatg aatggtctct gcccgcacac caaactgcgc cgcttttttc
    16561 gccgtctcct gcgcgccgcg ttcatcggaa tgccaggtga taccaatatc aaaaccgttt
    16621 tgtgctaata acaacgcaca cgctttgcca attcccgaat ctgatgccgt tacaattgcg
    16681 actttggtca tattcctctc cggatgaatc atacacagcc taagtatagg aaccctgtct
    16741 gaatcatctg gaaaaatcag gaatgataac cgccgcccag cgcgctggta agctgaatag
    16801 aggcatccag ccactggccc tgcaacagca agccgttaca ctgctcgcgc agtgccggga
    16861 ttttggcctc gctcacgcgg gaacccgcaa taatgccggc attaaagcgc gcttgcgcca
    16921 gaccgaccac acgctgcgcg tcatgctcaa tctgctgctg atgctgattt ttctgcgcca
    16981 gcgtctctac ctgactggcg gcgcgcgcca catcattaac cgcatctacc accgctttgt
    17041 tgtagttggc gatagaaagg ttgctttgcg ctttggcgat atcgaggttg gcattcagcc
    17101 tgccgctgtc gaaaatcggc agcgtcagcc cgccggtaat gccatattgc tgtgcggaat
    17161 ggcggaacag atcgctcaga tgtaacgcat cctgctgtaa aaaagccatc agattgatat
    17221 cgggataaaa cgcggccttc gcggcgtcaa tgctgctcaa cgaggattca atgtaccagt
    17281 gcgcggcctg tagatccgcc cggcgcgcca gcaacgaata ccccagttgc gacggtaact
    17341 ggctttcaac ggcggggaga ctcacctgac gcagcttgag cgccgccgat tgcgtattgg
    17401 ttaacgcgct gagccgcgct tcaataacct tcattttacc gttaacgtca ttcaactgct
    17461 gctgggtttt gctggcgtcg atatcggtct cgaccccttc aacagaagaa gtaataccgt
    17521 gttgatacag ctcccggttt accgccacca cgttttgctg ctcatgctcg atttgcatca
    17581 gcacattttt cagcgccgcc tgcgtctgcc actcccagta gagtcgcgcc acgccgcttg
    17641 ccagcaattg tcgggtctgc tcctgctccg cttcgcgcgc tttgaccgcc ccgatccgcg
    17701 cggtaacttc agcgcggttt ttcccccata aatccagatc ccagcccgcc gtcaggccga
    17761 atgtaccgtt ggtataccac ggcccggtcg ttcccgccgc ggggtcggta atcgcgaatg
    17821 gccccatcag cccttccgcg gacattcgct ggcgctcaat gtcggcagaa aagtcgagct
    17881 gcgggccgtc ctgcgcctca accgctttcg cctgcgcttc cgccagttga atacgctgtt
    17941 cagccacctg catatccggc gaatgctgta tggcattatc aatcagcgcg tcaagctgcg
    18001 catcgtgata cgccttccac cactggctat ccggccaacc gtttttcaat gccgccggca
    18061 ggctggaatc aacatgagaa gagggcgtct gctgggtcag cgactggcgg gtatcgtgca
    18121 taggggcgca gcccgccagc aaaataaaaa gcggtaagct cgctgtcgcg gcaaggaaag
    18181 aattacgatt catggaggtg ttctgataaa aaaaggtgcg cagagagtac gtcttacggc
    18241 gaactat
//
LOCUS       DAJVBX010000079        17957 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.079, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000079 DAJVBX010000000
VERSION     DAJVBX010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 17957)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17957)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17957
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.079"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            142..591
                     /gene="alaE"
                     /locus_tag="OPV72_002341"
     CDS             142..591
                     /gene="alaE"
                     /locus_tag="OPV72_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-alanine exporter AlaE"
                     /protein_id="HCR9914620.1"
                     /translation="MFSPQSRLRHAVADTFAMVVHCSVVNMLIEIFLSGMSFEQSLSS
                     RLVAIPVNILIAWPYGVYRDLIMRVARKASPAGWAKNLADVLAYVTFQSPVYIIILLT
                     VGAGWHQIVAAVSSNIVVSMLMGAVYGYFLNYCRRLFKVSSYHQAKA"
     gene            complement(626..976)
                     /locus_tag="OPV72_002342"
     CDS             complement(626..976)
                     /locus_tag="OPV72_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgaC family protein"
                     /protein_id="HCR9914621.1"
                     /translation="MYLRPDEVARVLEKAGFTVDVVTNKTYGYRRGENYVYVNREARM
                     GRTALIIHPRLKDRSSSLADPASDIKTCDHYQNFPLYLGGETHEHYGIPHGFSSRIAL
                     ERYLNGLFGDEKSD"
     gene            1138..1464
                     /locus_tag="OPV72_002343"
     CDS             1138..1464
                     /locus_tag="OPV72_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311560.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF883 domain-containing protein"
                     /protein_id="HCR9914622.1"
                     /translation="MLNKPNRNDVDDGVQDIQNDVNRLADSLEDVLKSWGSDAKDEAE
                     AARRKAQALLKETRARMQGRTRVKQAACDAMGCADTFVREKPWCSVGTAAAVGIFIGA
                     LLSLRR"
     gene            complement(1548..2882)
                     /locus_tag="OPV72_002344"
                     /pseudo
     CDS             complement(1548..2882)
                     /locus_tag="OPV72_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461729.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
     gene            2971..3402
                     /locus_tag="OPV72_002345"
     CDS             2971..3402
                     /locus_tag="OPV72_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HCR9914623.1"
                     /translation="MTTLRQPYYELSPEVYSALVQAKNALEKSTIDPTLMELIYLRVS
                     QINGCAFFLEMHSKALRKAGVNQAKLDALAGWRVSHHFNEQECAALAWAESVTHIAET
                     HAEDNVYLPLLDHFSAREISDLTFAIGLMNCFNRLAIGMRM"
     gene            3674..3919
                     /gene="nrdH"
                     /locus_tag="OPV72_002346"
     CDS             3674..3919
                     /gene="nrdH"
                     /locus_tag="OPV72_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HCR9914624.1"
                     /translation="MSITIYTRNNCVQCHATKRAMESRGFEFEMVNVDLVPDAADTLR
                     AQGFRQLPVVMAGDLSWSGFRPDMINRLPPTPHAANA"
     gene            3916..4326
                     /gene="nrdI"
                     /locus_tag="OPV72_002347"
     CDS             3916..4326
                     /gene="nrdI"
                     /locus_tag="OPV72_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HCR9914625.1"
                     /translation="MSALVYFSSSSENTHRFMQRLGLPATRIPLNERERIQVDEPYIL
                     VVPSYGGGGMAGAVPRQVIRFLNDEHNRARIRGVIASGNRNFGDAWGCAGDVIAQKCG
                     VPWLYRFELMGTQRDIDNVRKGVNEFWQQSPRSA"
     gene            4299..6443
                     /gene="nrdE"
                     /locus_tag="OPV72_002348"
     CDS             4299..6443
                     /gene="nrdE"
                     /locus_tag="OPV72_002348"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HCR9914626.1"
                     /translation="MATITPERVMQETMDYHALNAMLNLYDKAGHIQFDKDQQAIDAF
                     FAAHVRPHSVKFASQHERLETLVREGYYDDAVLARYDRAFVFRLFEHAHASGFRFQTF
                     LGAWKFYTSYTLKTFDGKRYLEHFEDRVTMVALTLAQGDETLATQLTDEMLSGRFQPA
                     TPTFLNCGKQQRGELVSCFLLRIEDNMESIGRAVNSALQLSKRGGGVAFLLSNLREAG
                     APIKRIENQSSGVIPVMKMLEDAFSYANQLGARQGAGAVYLHAHHPDILRFLDTKREN
                     ADEKIRIKTLSLGVVIPDITFRLAKENAQMALFSPYDIQRRYGKPFGDIAISERYDEL
                     IADPHVRKTYINARDFFQTLAEIQFESGYLYIMFEDTVNRANPIAGRINMSNLCSEIL
                     QVNSASRYDDNLDYTHIGHDISCNLGSLNIAHVMDSPDIGRTVETAIRGLTAVSDMSH
                     IRSVPSIAAGNAASHAIGLGQMNLHGYLAREGIAYGSPEALDFTNFYFYTITWHAVHT
                     SMRLARERGKTFAGFAQSRYASGDYFTQYLQDDWQPKTAKVRALFARSGITLPTREMW
                     LKLRDDVMRYGIYNQNLQAVPPTGSISYINHATSSIHPIVAKIEIRKEGKTGRVYYPA
                     PFMTNENLDMYQDAYDIGPEKIIDTYAEATRHVDQGLSLTLFFPDTATTRDINKAQIY
                     AWRKGIKSLYYIRLRQLALESTEIEGCVSCAL"
     gene            6454..7413
                     /gene="nrdF"
                     /locus_tag="OPV72_002349"
     CDS             6454..7413
                     /gene="nrdF"
                     /locus_tag="OPV72_002349"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HCR9914627.1"
                     /translation="MKLSRISAINWNKIQDDKDLEVWNRLTSNFWLPEKVPLSNDIPA
                     WQTLSAAEQQLTIRVFTGLTLLDTIQNIAGAPSLMADAITPHEEAVLSNISFMEAVHA
                     RSYSSIFSTLCQTKEVDAAYAWSEENPPLQRKAQIILAHYVSDEPLKKKIASVFLESF
                     LFYSGFWLPMYFSSRGKLTNTADLIRLIIRDEAVHGYYIGYKHQIALQKLSAIEREEL
                     KLFALDLLMELYDNEICYTEALYAETGWVNDVKAFLCYNANKALMNLGYEALFPPEMA
                     DVNPAILAALSPNADENHDFFSGSGSSYVMGKTVETEDEDWNF"
     gene            7768..8969
                     /gene="proV"
                     /locus_tag="OPV72_002350"
                     /pseudo
     CDS             7768..8969
                     /gene="proV"
                     /locus_tag="OPV72_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461735.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein ProV"
     gene            8962..10026
                     /gene="proW"
                     /locus_tag="OPV72_002351"
     CDS             8962..10026
                     /gene="proW"
                     /locus_tag="OPV72_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     permease ProW"
                     /protein_id="HCR9914628.1"
                     /translation="MADQTNPWDTAQVADTTTQTADAWGTPAGVATDGGSTDWLNSAP
                     APAPEHFSLLDPFHKTLIPLDSWVTEGIDWVVTHFRPLFQGIRVPVDYILNGFQQLLL
                     GMPAPVAIILFALIAWQVSGVGMGIAALISLIAIGAIGAWSQAMITLALVLTALLFCV
                     VIGLPMGIWLARSPRAAKIVRPLLDAMQTTPAFVYLVPIVMLFGIGNVPGVVVTIIFA
                     LPPIIRLTILGINQVPADLIEASRSFGASPRQMLFKVQLPLAMPTIMAGVNQTLMLAL
                     SMVVIASMIAVGGLGQMVLRGIGRLDMGLATVGGVGIVILAIILDRLTQAVGRDSRSR
                     GNRRWYTTGPVGLITRPFVK"
     gene            10096..11091
                     /gene="proX"
                     /locus_tag="OPV72_002352"
     CDS             10096..11091
                     /gene="proX"
                     /locus_tag="OPV72_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     substrate-binding protein ProX"
                     /protein_id="HCR9914629.1"
                     /translation="MRHTVIFASAFATLVTASAFAADLPGKGITVQPIQSTISEESFQ
                     TLLVSRALEKLGYTVNKPSEVDYNVGYTSIASGDATFTAVNWQPLHDDMYAAAGGDKK
                     FYREGVFVSGAAQGYLIDKKTAEQYNITNIAQLKDPKIAKIFDTNGDGKADMMGCSPG
                     WGCEAVINHQNKAFDLQKTVEVSHGNYAAMMADTITRFKEGKPVLYYTWTPYWVSDVM
                     KPGKDVVWLQVPFSSLPGEQKNIDTKLPNGANYGFPVNTMHIVANKAWAEKNPAAAKL
                     FAIMKLPLADINAQNAMMHAGKSSEADVQGHVDGWINAHQQQFDGWVKEALAAQK"
     gene            11256..12440
                     /locus_tag="OPV72_002353"
     CDS             11256..12440
                     /locus_tag="OPV72_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR9914630.1"
                     /translation="MTKPTHGLSPALIVLMSVATGLAVASNYYAQPLLDTIAHHFSLS
                     ASSAGFIVTAAQLGYAAGLLFLVPLGDMFERRTLIVSMTLLAAGGMLITASSQSLSMM
                     ILGTALTGLFSVVAQILVPLAATLATPATRGKVVGTIMSGLLLGILLARTVAGLLANL
                     GGWRTVFWVASALMALMAVALWRGLPKLKSDTHLNYPQLLGSVFSLFIHDKLLRTRAL
                     LGCLTFANFSILWTSMAFLLAAPPFSYSEGMIGLFGLAGAAGALGARPAGGFADKGKS
                     HLTTTFGLLLLLLSWLAIWLGRTSVLALIIGILVLDLTVQGVHITNQTVIYRLHPDAR
                     NRLTAGYMTSYFIGGAAGSLISASAWQHAGWAGVCLAGVTVALLNLLVWWRGFHRQEA
                     VN"
     gene            12937..13467
                     /gene="mprA"
                     /locus_tag="OPV72_002354"
     CDS             12937..13467
                     /gene="mprA"
                     /locus_tag="OPV72_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor MprA"
                     /protein_id="HCR9914631.1"
                     /translation="MDSSFTPIEQMLKFRASRHEDFPYQEILLTRLCMHMQGKLLENR
                     NKMLKAQGINETLFMALITLESQENHSIQPSELSCALGSSRTNATRIADELEKRGWIE
                     RRESDNDRRCLHLQLTEKGQAFLQEVLPPQHHCLHQLWSSLSTAEKDQLEHITRKLLT
                     RLDQMEQEGTVLEALR"
     gene            13594..14766
                     /gene="emrA"
                     /locus_tag="OPV72_002355"
     CDS             13594..14766
                     /gene="emrA"
                     /locus_tag="OPV72_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter periplasmic
                     adaptor subunit EmrA"
                     /protein_id="HCR9914632.1"
                     /translation="MSANAEIQPPQQPAKKKGKRKTALLLLTLLFVIIAVAYGIYWFL
                     VLRHIEETDDAYVAGNQVQIMAQVSGSVTKVWADNTDFVKEGDVLVTLDQTDAKQAFE
                     RAKTALASSVRQTHQLMINSKQLQANIDVQKTALAQAQSDLNRRVPLGNANLIGREEL
                     QHARDAVASAQAQLDVAIQQYNANQAMILNSNLEDQPAVQQAATEVRNAWLALERTRI
                     VSPMTGYVSRRAVQPGAQISPTTPLMAVVPATDLWVDANFKETQLANMRIGQPVTIIT
                     DIYGDDVKYTGKVVGLDMGTGSAFSLLPAQNATGNWIKVVQRLPVRVELDARQLEQHP
                     LRIGLSTLVTVDTANRDGQVLASQVRTTPVAESNAREINLAPVNKLIDDIVQANAG"
     gene            14783..16321
                     /gene="emrB"
                     /locus_tag="OPV72_002356"
     CDS             14783..16321
                     /gene="emrB"
                     /locus_tag="OPV72_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter permease
                     subunit EmrB"
                     /protein_id="HCR9914633.1"
                     /translation="MQQQKPLEGAQLIIMTIALSLATFMQVLDSTIANVAIPTIAGNL
                     GSSLSQGTWVITSFGVANAISIPLTGWLAKRFGEVKLFMWSTVAFAAASWACGVSSSL
                     NMLIFFRVVQGVVAGPLIPLSQSLLLNNYPPAKRSIALALWSMTVIVAPICGPILGGY
                     ISDNYHWGWIFFINVPIGIAVVLMTLHTLRGRETHTERRRIDAVGLALLVIGISSLQI
                     MLDRGKELDWFSSQEIIILTVVAVIAISFLIVWELTDDHPIVDLSLFKSRNFTIGCLC
                     ISLAYMLYFGAIVLLPQLLQEVYGYTATWAGLASAPVGIIPVILSPIIGRFAHKLDMR
                     RLVTFSFIMYAVCFYWRAWTFEPGMDFGASAWPQFIQGFAVACFFMPLTTITLSGLPP
                     ERLAAASSLSNFTRTLAGSIGTSITTTMWTDRESLHHAQLTESVTAYNPNAQAMYDKL
                     EGLGMTHQQASGWIAQQITNQGLIISANEIFWMSAGIFLVLLGLVWFAKPPFGAGGGG
                     GGAH"
     gene            complement(16370..17740)
                     /locus_tag="OPV72_002357"
     CDS             complement(16370..17740)
                     /locus_tag="OPV72_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate porin"
                     /protein_id="HCR9914634.1"
                     /translation="MKAKYLALMIGACFSHNLWAANDITIEQRLAELEQRVVNAEKRA
                     SDAEAQIRSLKQQQVAATPTVNVQSAEPIAADKTPPKLTLSGFSDIKFYGDVEFNMDA
                     ASRSGSLTSMRTSANKDWASGTNERWDINGRLLLGFDGYQRLDNGNFAGFSVQPLADL
                     TGKMNLDDAVFFFGRENDWKIKVGRFEAYDMFPLNQDTFIEYSGNTANDLYSDGYGYI
                     YMMKEGRGRSDSGGNFLLSKTIDNWYFEVNTLLENGSTLYTEKQYHGMDLTNDKNVAY
                     VRPVIAWQNGRFSTAIAMESNVVNNAYGYYENGKWIDQSDRTGYGFTMTWNGQKTDPE
                     DGAVINLNTAYMDATDETDFTAGVNALWHRFELGYIYAHNKIEAFNATNIDAVCEDDC
                     WITDPGNYDIHTIHASYLFPNVMDMKNFNIYLGAYASWVEANPNNGDNSEDARYGGRL
                     RFKYFF"
BASE COUNT         4149 a         4812 c         4626 g         4370 t
ORIGIN      
        1 acaaaaagcc tataaataaa aatattacgc tagttgatag ttattatata gggatatact
       61 ctatgaaaag acaaaagcgc tttataattt cactaccaac tatcacctca ttctgatcga
      121 tacgctacaa ggagcattaa catgttctct ccacagtcac gcttgcgtca tgccgtagca
      181 gacacgtttg cgatggttgt tcactgttct gttgtgaaca tgttgatcga gatattcctc
      241 tccggaatga gctttgagca gtcgctttct tccaggctgg tggcgatacc tgtcaacatt
      301 ttgattgcat ggccatacgg cgtttaccgc gatctgatta tgcgcgtcgc gcgtaaggca
      361 agcccggcgg gatgggccaa aaacctggcg gatgtattgg cttatgtcac ctttcagtca
      421 cccgtttata ttatcatctt gctgaccgtc ggcgccggct ggcatcagat agtggccgcc
      481 gtgagttcaa acattgttgt ttcaatgtta atgggcgcgg tttatggcta cttcctgaat
      541 tattgtcgtc gcctgtttaa agtgagcagc tatcatcagg ctaaggcata agttaacgtc
      601 gcgactggct ttgccagtcg cgcttttagt cgcttttttc gtcgccaaaa agcccattca
      661 gataacgttc taacgctatt cgggagctaa agccgtgggg aataccgtaa tgttcgtggg
      721 tctcgccgcc taaatagagc ggaaaatttt ggtagtgatc gcaggtttta atatccgaag
      781 ccgggtcagc cagtgatgag ctacggtctt ttaatctggg gtgaatgatc agcgcggtac
      841 gccccatacg cgcctcgcgg ttaacataaa cataattctc gccgcgtcga taaccatacg
      901 tcttattcgt caccacatcg acggtaaacc ctgccttttc cagtacccgc gccacctcgt
      961 caggtcgtaa atacatgttt tatcctcatt ctcttttact gcgggcttac cttacccgat
     1021 agcgcgttat caacgctttc agaaaagtcc agaaacgcat gatatcgccg taacaagcct
     1081 cagcaggtaa aaatatgaac tacactgaaa gctacatcga aatcaatgga ggatcatatg
     1141 cttaacaaac cgaaccgaaa cgacgtcgat gatggtgttc aggatattca gaatgatgtc
     1201 aatcgattag ccgacagtct ggaagatgtc cttaaatcct ggggaagcga tgcgaaagac
     1261 gaagccgagg ctgcgcgacg taaagcacag gcgttgctga aagagacccg ggcgcggatg
     1321 cagggtcgta ctcgcgtaaa acaagccgcc tgtgatgcga tggggtgcgc ggatacgttt
     1381 gtgcgtgaaa aaccctggtg tagcgtagga accgccgcag cggtggggat ttttatcggg
     1441 gcgctgctta gcctgcgtcg ctaacgacgt gcgctgccgg atggcgacat actttatggg
     1501 gcctgcatca ttgccgcagg cccaggtcgc gccattcggc gaaacggtta ctgtatcgcc
     1561 tgtcgaagct gacatgctac ctgtttcgcc atgccagcgg aagtaatatt ggtaaacgac
     1621 agtaaaatgc ccccctttcc tgacgaaacc actcgccaac gacttagcgc ctgtaccgcc
     1681 agtccggcct gattcgcttt tgctaccagc gctttatcat caccttcaac ctcaataacc
     1741 aattgaatac cgcctttctg taatgtcacg acaaatccct gttctgccag cgcctcttca
     1801 atccataacc gtcgctgagc ataatgttga cgcatctttt tcagatgccg ccagaaatgg
     1861 ccatcacgga taaaatcagc cagcgtgtgc tgccataaca acggtacgct acagggcatc
     1921 agcgacgcct gctggcggaa atgctcaatc tgctttatcg gcaccaccag ccaggcggta
     1981 cgtaatgccg gaaagagcga cttactgaac gttccggcgt aaatcactcg ctgcggggca
     2041 tccagactct tgagcggcgg aagcggttta ccgtgataac gaaattcgct gtcgtagtca
     2101 tcttcaataa tccaggcctg cacattcgcc gcccatgcca gaagttgccg tcggcgagtt
     2161 aacgacagcg ccacccccaa cggactttga tgggcgggcg tcaccaatgc aaagcgtccc
     2221 tgcgggcaat cccgcatccc cgctgcgaca ttcagcccat cggcatcgac cggaatcggc
     2281 gccagcgtaa tcccctcctg cgttatcacc gggcgaatta acggaaagcc gggatcttcc
     2341 acccacatgc tgtctcccgg cacagacaat gtacgcagga ttagccgcat agaatccgca
     2401 tatccggagg taataaatac ctgttccggc agacattcaa tgctacgcga aacccgcagg
     2461 taatcgacta tcgcctagcg caaaatcgcc tcgccgcaga cgtcgcctaa tgccagatcg
     2521 aagcgtgtct gcgtgcgcaa ccgacgcccc attactcgcg cccacttctc gcgtggaaag
     2581 agatccagcg ccggtaaccc catctgaaag ggtttcggtt ccggactttc tccggcaaaa
     2641 acagcgggta tcggcggcgc cgtctcaaac cgtagagcgt tgctcacaaa cgtgcctgcc
     2701 tggccacgtc gctccagcca gccctgcgct accagctcgc cataggcatt ttccaccgtg
     2761 gcgcgagaaa cgcccagttc ctgcgcccac gtccgactgg aaggcaaacg cgttccgggc
     2821 gcgagttctc cttgctcaat ggccgttttt aactgacgag cgatgtactg atagcgcggc
     2881 atatggtctg ctttttctgt aaaaatatgg ctctctttta cagaccatta tagtgctaca
     2941 gtgctcgtca tcaacacgag gagaaacata atgacgacgt tacgccaacc ctattatgaa
     3001 ctgagcccgg aggtttacag cgctctggtg caggcgaaaa acgcgctgga aaagagcacg
     3061 attgacccca ctctgatgga gctgatttac ctgcgtgttt cgcaaataaa tggttgtgca
     3121 tttttcctgg agatgcacag taaagcgctg cgtaaggctg gcgtgaatca agctaaatta
     3181 gatgcgctgg caggatggcg ggtaagccac catttcaacg agcaagagtg cgcggcgtta
     3241 gcctgggcgg aatcggtgac gcacattgct gaaacccacg ccgaagataa tgtttacctg
     3301 ccgctgctcg atcatttcag cgcgcgtgaa atcagcgatc tgaccttcgc tattggttta
     3361 atgaactgct ttaaccgtct ggcgatcggt atgcgaatgt gacgcattgt tgccggatag
     3421 cgctgatgtc agccaactct gttatgcgtg aacctgcagg ccggatcggg cgttcacgcc
     3481 gccatccggc aaaaattagc catgccgccc ctaccccgct gcgttcatca gcggcgttaa
     3541 aatcaatcga aaattcccat atcttgtatg gttgaatctt aattcaacta catctagtat
     3601 ttcgtgtatc aacacacgac aatccgacgc gtttcatcgc gccgttttct cattttaaat
     3661 ggaaatacga atcatgagca ttactattta cactcgcaat aactgtgttc agtgccacgc
     3721 cacaaagcgg gcgatggaaa gccgtggatt tgaatttgag atggtgaacg tcgatctggt
     3781 gccggatgca gcggatacgc tccgggcgca agggtttcgt caattaccgg tggtgatggc
     3841 gggcgatttg agctggtctg gcttccgtcc ggacatgatt aaccgtctgc ccccgacgcc
     3901 ccacgcggca aacgcatgag cgcgctcgtc tacttctcca gcagctctga aaatacgcac
     3961 cgttttatgc agcgtctggg gctgcccgcc acgcgtattc cgctcaatga acgggagcga
     4021 attcaggtag acgaaccgta cattctggtt gtgccgtcat acggcggcgg cgggatggcc
     4081 ggtgcggtgc cgcgacaggt gatccgcttt ttaaatgatg aacacaaccg ggcgcgcatt
     4141 cgcggcgtca tcgcctccgg taaccgcaat ttcggcgatg cctggggatg cgctggcgat
     4201 gtgatagcac aaaaatgcgg cgtcccctgg ctgtaccgct ttgagctcat gggcacacaa
     4261 cgcgacatcg ataacgtccg aaaaggagta aatgaatttt ggcaacaatc accccggagc
     4321 gcgtaatgca ggaaaccatg gattaccacg ccctgaacgc gatgctgaat ctttacgata
     4381 aagcaggcca tattcagttc gacaaggacc agcaggcgat cgacgccttc tttgccgccc
     4441 acgtccgccc gcattccgtg aagtttgcca gccagcatga acgtctggag acgctggttc
     4501 gggaagggta ttacgatgac gccgtcctcg cgcgttacga ccgcgccttc gtcttccgcc
     4561 tgttcgagca cgcccacgcc agcggctttc gcttccagac gtttcttggc gcctggaagt
     4621 tctataccag ttacacgctg aaaaccttcg acggcaaacg ttatctggaa cactttgaag
     4681 atcgggtgac aatggtggcg ttgacgctgg cgcagggtga cgaaacgctg gccacccaac
     4741 tgaccgatga aatgctttct ggtcgctttc agcccgctac cccgactttt ttaaattgcg
     4801 gtaaacagca gcgtggggaa ctggtctcct gcttcctgct ccgtatcgaa gacaatatgg
     4861 aatcgatcgg gcgagcggtg aattcggcgc tgcaactctc caaacgcggc ggcggcgtcg
     4921 catttttact ctccaatctg cgcgaggcgg gcgcgccgat caaacgcatt gagaatcagt
     4981 cttccggcgt gatcccggtg atgaaaatgc tggaagacgc gttttcgtat gccaaccagc
     5041 ttggcgcgcg ccaaggggcc ggcgcggttt atctccatgc gcaccatccg gatattctgc
     5101 gttttctgga taccaaacgg gaaaatgccg acgaaaaaat ccggatcaaa acgctctctc
     5161 tcggcgtggt gatcccggac atcaccttcc ggctggcgaa agaaaacgcg caaatggcgc
     5221 tcttttcgcc ctatgacata caacgacgct acggcaaacc gtttggcgat atcgccatta
     5281 gcgaacggta cgatgaatta attgccgatc cgcacgtgcg caaaacctat attaacgccc
     5341 gtgacttttt tcaaacactg gcggaaattc agttcgaatc cgggtatctc tacatcatgt
     5401 ttgaagatac ggtaaaccgc gcgaatccta ttgctggtcg cattaatatg agcaacctgt
     5461 gctcggaaat tttacaggtc aatagcgcct ctcgttacga cgataacctt gactataccc
     5521 acatcgggca tgacatctcc tgcaatctcg gctcgctgaa tatcgctcac gtcatggatt
     5581 caccggacat tggccgtacc gtagaaaccg ctattcgcgg cctgacggcg gtgtcggaca
     5641 tgagccatat acgcagcgtg ccctcaatag ccgccggtaa tgccgcctct catgccatcg
     5701 gtctgggcca gatgaatctg catggctatc tggcgaggga aggtattgcc tacggttcgc
     5761 cggaggcgtt ggatttcacc aatttctatt tttacaccat tacctggcat gccgtgcata
     5821 cttcaatgcg gctggcccgc gaacgcggca aaaccttcgc cggatttgcg cagtcgcgct
     5881 atgccagcgg cgactatttt acgcagtatt tacaggacga ctggcaaccg aaaacggcga
     5941 aagtcagggc gctatttgcc cgcagcggca ttacgctgcc cacacgcgaa atgtggctaa
     6001 agctgcgcga cgatgtgatg cgctatggca tctataacca aaatttgcag gcggtgccgc
     6061 cgaccggttc gatttcttac attaatcatg cgacctccag cattcatccg attgtggcca
     6121 aaattgagat tcgcaaagag ggcaaaaccg ggcgtgtgta ttaccccgcg ccgtttatga
     6181 ctaatgaaaa cctggacatg tatcaggatg cttacgatat cggtccggaa aaaattattg
     6241 atacctatgc cgaggccacg cgccacgtcg atcaaggact gtcgctcacc ctgtttttcc
     6301 ccgataccgc cacgacccgc gatatcaaca aagcgcagat ctatgcctgg cgaaaaggta
     6361 ttaagtcact gtattacatc cgacttcgcc agttggcgct ggaaagtact gaaattgaag
     6421 gctgcgtatc ctgcgcgcta taaggaaagc catatgaaat tatctcgtat tagcgccatc
     6481 aactggaaca agatccagga cgacaaagat ctggaggtgt ggaaccggct gaccagtaac
     6541 ttctggctgc cggaaaaagt gccgttatcg aatgatattc cggcctggca gacgctgagc
     6601 gccgccgaac agcagctcac cattcgcgtg tttacgggtc ttacgctgct cgacactatc
     6661 cagaacatcg caggcgcgcc gtcgttaatg gcagatgcca tcacgccgca tgaagaggcc
     6721 gtactgtcga acatcagctt tatggaagcg gtacacgccc gctcttacag ttctattttc
     6781 tccacgctgt gccagacgaa agaggttgat gccgcctacg cctggagcga agaaaaccca
     6841 ccgcttcagc gtaaggcgca gattatttta gctcattacg tcagcgatga accgctaaag
     6901 aaaaagattg ccagcgtctt tttagagtct tttctgttct attccggctt ctggttgccg
     6961 atgtatttct ccagccgcgg taagctcacg aacactgccg acctgattcg tttaatcatt
     7021 cgcgatgaag cggttcacgg ttattatatt ggctataagc atcagatagc gctacaaaaa
     7081 ctatcggcaa tcgagcgtga agagttaaag cttttcgcgc tggatttatt gatggaactg
     7141 tacgacaacg aaatctgcta cacagaagcg ttatatgcgg aaaccggctg ggttaacgac
     7201 gtcaaagcct tcttgtgcta caacgccaat aaagccttaa tgaacctggg ttatgaggcg
     7261 ttatttccgc cggagatggc agacgtgaat cccgcaatcc ttgccgcgct ctcgccgaat
     7321 gccgacgaaa accatgattt cttttccggc tcaggttcat cttatgtgat ggggaaaacg
     7381 gtcgaaaccg aagacgaaga ctggaatttt taaccttgcg ggcatgggaa ataacgttac
     7441 attttccatg cctttatttc aagcaatacc gggttaaatc gcgcaaatat tacaacatgt
     7501 cctacactca atacgagtga cattattcac ctggattcct ccaattcagg tggatttttg
     7561 ctggttgtct caaaaaatat ctctccctcc ccattcgcgt tcagccctta tatcatggga
     7621 aatcacagcc gatagcacct cgcaatattc atgccagaag caaattcagg gttgtctcag
     7681 attctgagta tgttagggta gaaaaaggta actatttcta tcaggtaaca tatcgacata
     7741 agtaaataac aggaatcatt ctattgcatg gcaattaaat tagaagtgaa gaatctgtat
     7801 aaaatatttg gagagcatcc gcagcgtgcc ttcaaatata ttgaaaaggg actatcgaaa
     7861 gagcaaatac tggaaaaaac ggggctatcg cttggcgtta aagacgccag tctggccatt
     7921 gaagaaggcg agatatttgt catcatggga ttatccggct cgggtaaatc cacaatggta
     7981 cgccttctca atcgcctgat tgaacccacc cgcgggcagg tactgattga cggtgttgat
     8041 attgccaaaa tatcagacgc tgagcttcgc gaggtgcgca ggaaaaagat tgcgatggtc
     8101 ttccagtcat ttgcgctcat gccgcatatg accgtgctgg ataatacggc attcggtatg
     8161 gaattagcgg gcatcgcggc gcaagagcgt cgcgaaaagc gctggacgcc ttgcgtcagg
     8221 tggggcttga gaattacgct cacgcctatc cggatgaact ttccggtggg atgcgtcagc
     8281 gtgttgggct tgcccgcgcg ctggcaatca accctgatat cttattaatg gatgaagcgt
     8341 tttccgccct cgatccatta attcgtaccg aaatgcagga tgagctggtg aaattacagg
     8401 cgaaacatca gcgcaccatt gtctttattt cccacgatct tgatgaggct atgcgtattg
     8461 gcgacaggat tgccattatg caaaatggcg aggtcgtaca ggttggtacg ccggatgaga
     8521 tcctgaataa tccggcaaat gattatgtcc gcacgttctt ccgtggcgtg gatattagtc
     8581 aggtctttag cgccaaagat attgcccgtc gcagtccggt cggcttaatt cgtaaaacgc
     8641 caggttttgg tccccgttcg gcactgaaat tattacagga tgaagaccgt gaatatggtt
     8701 acgtcattga gcgtggcaat aaattcgtgg gcgtcgtgtc catcgactca ttaaaagcgg
     8761 cattaagcca ggcgcaaggg attgaagcgg cgcttatcga cgacccttta gtcgttgatg
     8821 cgcaaacccc actcagcgag ttgctctctc acgtcggcca ggcgccctgc gcggtgccgg
     8881 ttgtcgatga agaacaccag tatgttggca ttatttcaaa acgtatgttg ctacaggctt
     8941 tagatcgcga ggggggtaac aatggctgat caaacgaatc cgtgggatac cgcacaggtg
     9001 gccgatacga cgacgcaaac ggctgatgcc tggggaacac cggcaggcgt agccacggac
     9061 ggcggcagta ccgactggtt gaacagcgcg cccgcgccag cccctgaaca cttttctctt
     9121 ctggacccgt tccataagac gcttatcccg ctggatagct gggtcacaga gggaatcgac
     9181 tgggtcgtca cccatttccg tccccttttt caggggattc gtgtgccggt ggattacatc
     9241 cttaacggct ttcagcaact gctgctggga atgcccgccc ctgtggcgat tattctcttt
     9301 gcgctgattg cctggcaggt ttccggtgtg ggcatgggga tcgcggcgct gatatcgctg
     9361 atcgccatcg gcgcgatcgg cgcctggtcg caggcgatga ttaccctggc gctggtgctg
     9421 accgccctgt tgttctgcgt cgtgatcgga ttaccgatgg gaatctggct ggcgcgcagc
     9481 ccgcgcgcgg ccaaaatagt tcgtccgctg ctggatgcga tgcagaccac gcccgcgttt
     9541 gtctatctgg tgccgattgt catgttattc ggcatcggta acgtgccggg cgtggtggtg
     9601 acgattattt ttgctctacc gccgattata cgcctgacga tcctgggcat taaccaggtg
     9661 cctgccgact taattgaagc gtcgcgctcg ttcggcgcca gcccgcgcca aatgttgttc
     9721 aaagtgcaac taccgctggc gatgcccacc attatggcag gcgttaatca gacgctgatg
     9781 ctggctctct caatggtcgt catcgcctcg atgattgcgg tcggtgggct tggccagatg
     9841 gtactacgcg gcattggtcg tcttgatatg gggctggcaa ccgtcggcgg cgtcggcatt
     9901 gtgattctcg ccatcattct ggaccgtctg acgcaggccg tcgggcgcga ctcgcgtagc
     9961 cgcggtaacc gtcgctggta taccaccggt cctgttgggc taatcacccg ccctttcgtt
    10021 aagtaactct cctgacgccc ggtgacattg cgcttaccgg gcttacaact ccctaccata
    10081 attaaaggaa caacgatgcg acatactgtg atatttgcct cagcgtttgc cacccttgtc
    10141 accgccagcg ctttcgctgc cgacctgcct ggcaaaggca ttaccgtcca acctatccaa
    10201 agcacgattt ctgaagagtc cttccagacg ttactggtca gccgggcgct ggaaaagttg
    10261 ggttataccg taaataagcc gagtgaagtc gattacaacg taggctatac ctccatcgcc
    10321 tctggcgatg cgacgtttac cgccgtgaac tggcagccgc tgcatgatga tatgtatgcc
    10381 gcagcaggcg gagacaaaaa gttttaccgc gagggcgtct tcgtctccgg cgctgcgcag
    10441 ggctatctga tcgataaaaa aaccgccgag cagtacaaca tcactaatat cgctcaacta
    10501 aaagatccga aaatcgccaa aatcttcgat accaatggcg acggaaaagc ggacatgatg
    10561 ggctgctcgc cgggctgggg ctgcgaagcc gtaatcaatc accagaataa agcgtttgat
    10621 ctgcaaaaaa ccgttgaggt cagccacggt aactatgcgg cgatgatggc tgataccatt
    10681 acccgtttta aagaaggcaa gccggtgctg tattacacct ggaccccgta ctgggtgagc
    10741 gacgtaatga agccgggtaa agatgtcgtc tggctacagg tgccgttctc ctccctgccg
    10801 ggcgaacaga aaaatattga tactaaactg ccgaacggcg cgaactatgg gttcccggtc
    10861 aatactatgc atattgtcgc caataaggca tgggcggaga aaaatccggc ggcggcgaaa
    10921 ctgttcgcca tcatgaagct gccgctggcg gatatcaacg cgcagaacgc catgatgcat
    10981 gccggtaaat cgtctgaagc cgatgttcag ggccacgtag acggctggat caacgcccac
    11041 cagcagcagt ttgacggctg ggtgaaagaa gcgctggccg cgcagaaata atatcgtttt
    11101 ttatgccgga taaggcgcag ttcatgcgcc gctatccggc caacgcaatc tctcctcaaa
    11161 gcgcacgatt catcacgtca ctgttcccct ttattcatca acatccgcta tgattgtttt
    11221 cccaggaaat aattatctaa atcacgatta ccataatgac gaaacccact catgggctta
    11281 gcccggcgct gatcgtttta atgtctgtgg ccacgggtct ggcggtcgcc agcaactact
    11341 atgcccagcc gctgcttgat accatcgcgc atcacttttc gctttccgcc agctccgcag
    11401 ggtttatcgt taccgccgcg cagttgggct atgccgctgg cctgttgttt ctggtgccgc
    11461 tcggcgacat gtttgaacgc cgaacgctga ttgtctccat gacgttgctg gcggctggcg
    11521 gaatgctgat cactgccagc agtcagtcgc ttagcatgat gatactcgga acggccttaa
    11581 ccggactgtt ctccgtggtg gcgcagattc tggttccgct ggccgccacg cttgcgacgc
    11641 ccgccacccg cggtaaagtg gtcggcacca ttatgagcgg cctgttgctg gggatcctgc
    11701 tggcgcgaac ggtcgccgga ctgctggcaa acctcggcgg ttggcgcacc gtattttggg
    11761 tagcgtcggc gctgatggcg ctgatggccg tcgcgttgtg gcgcggactg ccaaagctca
    11821 aatccgacac ccatcttaac tacccgcaac tgttgggttc tgtattcagc ctgtttattc
    11881 acgataagct gctgcgtacc cgcgcgctgc tgggctgtct gacctttgct aatttcagca
    11941 tcctctggac gtcaatggcc tttttgctcg ccgcgccgcc gtttagctat tccgagggga
    12001 tgattggcct gtttggcctg gcgggggccg ccggcgcttt aggcgcgcgt ccggctggcg
    12061 gatttgccga taaaggtaaa tctcacctca ccaccacgtt cggcttactg ctgctgttac
    12121 tctcctggct ggctatctgg cttgggcgca cctcggtact ggcgctgatt attggtattc
    12181 tggtactgga cctcaccgtt cagggggtac atatcaccaa tcagacggtc atctatcgtt
    12241 tgcatccgga tgcgcgtaac cggctcaccg ccggctatat gaccagctac tttatcggtg
    12301 gcgccgcggg gtcgctgatt tccgcctccg cctggcaaca tgccggctgg gccggcgttt
    12361 gtctggcggg tgtcacggta gccttactta atttactggt ctggtggcga ggttttcacc
    12421 gacaggaagc cgtaaattaa gcggatagtg agcgtttacc tttgtttaag ctccttaggg
    12481 tgttaaggag ctccccagtc tgttaaggtt atgctattca tttatcatgg ttatttttat
    12541 accggtgaag aataatataa ttctatggaa agccctgcat ccccatctgc tcccaggcca
    12601 atagcgcccg ttcaaggatt cgaaggtcgt tcaccgatag ctattcgtga tattccggtg
    12661 gcttttgcat cgggttgtaa ggccgtttac ccggctttcg cccctcccgc ttatcgttct
    12721 ctcctgattt tttcatgcag gcactcacgc ttttctcgtc attcctggat ttgccgcagg
    12781 cggcgcttta ccgggcccaa tgttcccgct gacgtctcag tctgcgtatc attggttgct
    12841 ttatagcctg aaagaatgat tttgtattaa taatacattt actttatttg tcactgtcgt
    12901 tactatatcg gctgaaatta atgaggtcat gcccaaatgg atagttcgtt tacgcccatt
    12961 gaacaaatgc taaaatttcg cgccagccgt cacgaagact ttccttacca ggaaattctt
    13021 ttgactcgtc tttgtatgca catgcaaggc aagctcctgg aaaaccgcaa taaaatgctg
    13081 aaggctcaag ggattaacga gacgttgttt atggcgttga ttacgctgga gtctcaggaa
    13141 aaccacagta ttcagccgtc tgaattaagc tgcgcgctgg gttcatctcg caccaatgcg
    13201 acacgcattg cagatgagct ggaaaaacgc ggctggattg agcgtcgtga gagcgataac
    13261 gaccgccgtt gcctgcatct gcaattaacg gagaaaggcc aggcattttt gcaagaagtg
    13321 cttccgcctc agcatcattg tctgcatcaa ctctggtcat cacttagcac agccgaaaaa
    13381 gatcaacttg agcacatcac tcgtaaactc ctgacgcgtc ttgatcaaat ggagcaggaa
    13441 ggcactgttc ttgaggcgct gcgctaaagc gccgacccgc tcaaaaatcc agattaataa
    13501 caggaaagcg gacaggccgg cacgcgttac tgctggcctt tctgacaaca ggtcggctca
    13561 gccgatgtga ataataagat cgtggagaac aacatgagcg caaatgcgga gatccaaccc
    13621 ccgcagcaac cggctaagaa gaaaggcaaa cgcaaaacag cgctgctact tcttaccttg
    13681 ctctttgtta ttattgccgt ggcatatgga atttattggt ttttagtatt gcgtcatatt
    13741 gaagagacag atgatgctta cgtggcaggg aaccaggttc aaatcatggc gcaggtgtca
    13801 ggcagcgtga cgaaagtctg ggctgataac accgactttg taaaagaggg cgatgttctg
    13861 gtcacgctcg atcagactga cgccaaacaa gcgtttgaaa gagccaaaac ggcgctggcc
    13921 tccagcgtgc gccagacgca ccagttgatg attaacagta agcagttgca ggcgaatatc
    13981 gacgtgcaaa aaaccgccct ggcgcaagcg cagagcgacc ttaaccgtcg tgtgccgctg
    14041 ggtaatgcca atcttattgg ccgggaagag ctgcaacacg cccgcgatgc cgtcgccagc
    14101 gcgcaggcac agcttgatgt cgccattcaa cagtacaatg ccaaccaggc aatgatactt
    14161 aacagtaatc tggaagatca gcctgcggtt caacaagcgg cgaccgaagt gcgtaacgcc
    14221 tggctggcgc tggagcgtac tcgcatcgtc agtccaatga ccggttatgt ctcccgccgc
    14281 gccgtccagc ctggcgcgca gatcagcccc accacgccgc tgatggccgt ggtgcctgca
    14341 accgatctgt gggtggacgc taactttaaa gagacccaat tagcgaatat gcgcattggg
    14401 cagccagtga cgattattac tgacatttat ggcgacgacg taaaatacac cggtaaagtc
    14461 gtcggtctgg atatggggac aggtagcgcc ttctccctgc tgcccgcgca aaatgcgacg
    14521 ggtaactgga ttaaagtggt tcaacgtctg ccggtacgcg tcgaactgga cgcccgccag
    14581 ttagaacaac atccgctgcg cattggttta tcgacgctgg tcaccgtgga taccgctaat
    14641 cgcgacggtc aggtactggc cagccaggta cgaacgacgc cggttgccga aagtaacgca
    14701 cgcgaaatta atctcgcgcc ggtcaataaa ctgatcgacg acatcgtaca ggctaacgcg
    14761 ggttaatcct gaggtgcgtg tgatgcaaca gcaaaaaccg ctggaaggcg cgcagctcat
    14821 catcatgacg atcgcgctgt cgctggcgac attcatgcag gtgctggact ccaccattgc
    14881 caacgtggcg attccgacca tcgccgggaa cctgggttct tccctaagcc aggggacatg
    14941 ggttatcacc tctttcgggg tggcgaacgc tatctcgatt cccttaaccg gctggctggc
    15001 gaagcgtttt ggcgaagtca aactgttcat gtggtcgacg gtcgcctttg ccgcggcctc
    15061 ctgggcctgt ggcgtatcca gcagcctgaa catgctgatc ttcttccgcg tggtgcaggg
    15121 cgtggtcgcc gggccgctga ttccgctctc gcaaagcctg ttgctgaata actatccgcc
    15181 tgcaaagcgc tccattgcgc tggcgctctg gtcaatgacc gtcattgtcg cgccgatttg
    15241 cggcccgatt ctggggggct acatcagtga taattaccac tggggatgga ttttcttcat
    15301 caacgtgccg attggcatcg ccgtcgtcct gatgacgtta cacacgctgc gcggacgtga
    15361 aactcatacc gaacggcgac gtattgacgc cgtcgggctg gcgttactgg tgattggcat
    15421 cagcagcctg caaattatgc tcgaccgcgg taaagagctg gactggttct cctcgcagga
    15481 aattatcatc ctgaccgtgg tcgccgtcat cgccatcagt ttcctgatcg tctgggaact
    15541 gaccgacgat caccctatcg tcgatctttc tctttttaaa tcgcgtaact tcactattgg
    15601 ctgcctgtgc atcagccttg cctatatgct ctatttcggc gccattgttc tattgccgca
    15661 gcttttgcaa gaggtgtacg gctataccgc aacgtgggca ggtctggcgt cggcgccagt
    15721 cggtattatt ccggtaattt tgtcgccgat tatcggacgc ttcgcgcata aactggatat
    15781 gcgcaggctg gtcacattca gcttcattat gtacgccgtc tgtttttact ggcgcgcctg
    15841 gacgttcgaa ccgggtatgg atttcggcgc ttccgcatgg ccgcagttta ttcaaggatt
    15901 tgccgtcgcc tgcttcttta tgccgctgac caccattacg ctctccgggt taccgcccga
    15961 acggctggcg gcggcatcaa gcctgtcgaa cttcacgcga acgctggcgg gctccattgg
    16021 cacctcgatt accaccacta tgtggaccga tcgtgagtcg ctacaccatg cgcagctcac
    16081 cgagtcggtt acggcgtata atccaaacgc tcaggctatg tacgataaac tggaaggctt
    16141 agggatgacg caccaacagg cgtcaggctg gatagcccag caaatcacga atcaggggct
    16201 gattatttcc gccaacgaaa tcttctggat gtcggcgggg atcttcctgg tgctgctcgg
    16261 cctggtgtgg ttcgccaaac cgcccttcgg tgcgggcggc ggcggcggtg gcgcgcacta
    16321 actatctgat aaaagggatc tacggatccc ttttttagta gaccaacaat cagaagaaat
    16381 atttgaatct cagacgcccg ccgtaacgcg catcttcact gttatcgcca ttattcggat
    16441 tggcctctac ccatgaagca taggcgccga ggtagatgtt aaagtttttc atatccatca
    16501 cgttggggaa taaatatgag gcatgaatag tgtggatgtc ataattgccg ggatcggtga
    16561 tccagcaatc gtcctcacaa acggcatcga tattggtagc attaaaggct tcgattttgt
    16621 tatgcgcata gatataaccc agttcaaatc gatgccacag cgcattcacc ccagcggtaa
    16681 aatctgtctc atcggtcgca tccatataag cggtattcag gttaataact gcgccatctt
    16741 ccgggtcagt tttttgacca ttccaggtca tggtaaaacc atagcccgta cgatctgact
    16801 gatcgatcca cttcccattc tcataatagc cataggcgtt gttaacgacg ttactttcca
    16861 tcgctatcgc cgttgaaaaa cgcccgtttt gccaggcaat aaccggacgg acgtaagcca
    16921 cgtttttatc gttggttaaa tccattccgt ggtactgctt ctcggtatat aacgtactgc
    16981 cattttccag caatgtgtta acttcgaaat accagttgtc gatggttttg ctcagcagga
    17041 agttaccccc actgtcgcta cgtccccgtc cttctttcat catatagata tagccgtaac
    17101 cgtcactgta aagatcgttc gctgtattcc ccgaatattc aataaatgta tcctgattca
    17161 gcgggaacat atcgtaggct tcaaaacgac caaccttaat tttccagtca ttctcacgac
    17221 caaagaagaa aacggcatca tcaaggttca ttttcccggt cagatccgcc agaggctgta
    17281 cagagaatcc ggcaaaatta ccgttgtcca gccgctggta gccatcaaag cccagcaaca
    17341 ggcgcccgtt aatatcccag cgttcattgg ttcctgatgc ccaatcttta ttcgctgacg
    17401 ttctcatcga ggtcaggcta ccggaacggc ttgccgcatc catattaaat tcgacatcgc
    17461 catagaactt aatatcgctg aatccggata aggtcagctt cggcggcgtt ttatctgctg
    17521 caatgggctc ggcggactgg acattcaccg tcggtgtagc ggcgacctgc tgctgtttca
    17581 gcgagcgaat ttgcgcctcg gcatcggatg cccgtttttc agcattaaca acacgttgct
    17641 ccagttcagc cagacgctgc tcaatagtga tatcattcgc tgcccaaagg ttatgagaaa
    17701 agcaagcacc gatcatcagc gccaaatatt tagccttcat tttttatccc ttaagtttga
    17761 tgtataccag ataagatttg ctaaaaaccc catcgaccgg ctattagtag agtcttgtta
    17821 ttacctggat atctggcgca ttccattatg tttttctatt aattatttat gatttttagt
    17881 ttatgtgatc aatacactct ggcatcgtga gttatccgcc ttttctgttt accagatcac
    17941 attttattat ttaacag
//
LOCUS       DAJVBX010000080        17956 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.080, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000080 DAJVBX010000000
VERSION     DAJVBX010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 17956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17956
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.080"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            322..1911
                     /gene="purH"
                     /locus_tag="OPV72_002358"
     CDS             322..1911
                     /gene="purH"
                     /locus_tag="OPV72_002358"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HCR9914635.1"
                     /translation="MQQRRPVRRALLSVSDKAGIIEFAQALSARGVELLSTGGTARLL
                     AEKGLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDAIMEQHHIAPIDMVV
                     VNLYPFAETVAREGCSLADAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYDAIIKEM
                     DANEGSLTLDTRFDLAIKAFEHTAAYDSMIANYFGSMVPAYHGESKEAAGRFPRTLNL
                     NFIKKQDMRYGENSHQQAAFYIEENVKEASVATAQQIQGKALSYNNIADTDAALECVK
                     EFNEPACVIVKHANPCGVAVSTSILDAYDRAYKTDPTSAFGGIIAFNRELDAETAQAI
                     ISRQFVEVLIAPSASEEALKITSAKQNVRVLTCGQWASRVPGLDFKRVNGGLLVQDRD
                     LGMVSEAELRVVSKRQPTEQELRDALFCWKVAKFVKSNAIVYAKENMTIGIGAGQMSR
                     VYSAKIAGIKAADEGLEVKGSAMASDAFFPFRDGIDAAAAVGVSCVIQPGGSIRDDEV
                     IAAADEHGIAMIFTDMRHFRH"
     gene            1927..3216
                     /gene="purD"
                     /locus_tag="OPV72_002359"
     CDS             1927..3216
                     /gene="purD"
                     /locus_tag="OPV72_002359"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HCR9914636.1"
                     /translation="MKVLVIGNGGREHALAWKAAQSPLVDTVFVAPGNAGTALEPALQ
                     NVAIGVTDIPALLSFAQNEKIDLTIVGPEAPLVIGVVDAFRAAGLKIFGPTEGAAQLE
                     GSKAFTKDFLARHQIPTAEYQNFTEIEPALAYLREKGAPIVIKADGLAAGKGVIVAMT
                     LEEAEAAVHDMLAGNAFGDAGHRIVIEEFLDGEEASFIVMVDGEHVLPMATSQDHKRV
                     GNGDTGPNTGGMGAYSPAPVVTDEVHQRTMERIIWPTVKGMAAEGNTYTGFLYAGLMI
                     DKQGNPKVIEFNCRFGDPETQPIMLRMKSDLVDLCLAACDGKLDEKTSEWDERASLGV
                     VIAAGGYPGSYSTGDEIHGLPLEEVADGKVFHAGTKLADDDRVLTSGGRVLCATALGH
                     TVAEAQKRAYALMTDIRWDGSFSRNDIGWRAIEREQN"
     gene            complement(3213..4538)
                     /gene="zraR"
                     /locus_tag="OPV72_002360"
     CDS             complement(3213..4538)
                     /gene="zraR"
                     /locus_tag="OPV72_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent response regulator
                     transcription factor ZraR"
                     /protein_id="HCR9914637.1"
                     /translation="MIRGKIDILVVDDDVSHCTILQALLRGWGYNVALAYSGHDALAQ
                     VREKVFDLVLCDVRMAEMDGIATLKEIKALNPAIPILIMTAFSSVETAVEALKAGALD
                     YLIKPLDFDRLQETLEKALAHTRETGAELPSASAAQFGMIGSSPAMQHLLNEIAMVAP
                     SDATVLIHGDSGTGKELVARALHACSARSDKPLVTLNCAALNESLLESELFGHEKGAF
                     TGADKRREGRFVEADGGTLFLDEIGDISPLMQVRLLRAIQEREVQRVGSNQTISVDVW
                     LIAATHRDLAEEVSAGRFRQDLYYRLNVVAIEMPSLRQRREDIPLLADHFLRRFAERN
                     RKAVKGFTPQAMDLLIHYDWPGNIRELENAIERAVVLLTGEYISERELPLAIAATPIK
                     AENSAEIQPLVDVEKEVILAALEKTGGNKTEAARQLGITRKTLLAKLSR"
     gene            complement(4544..5941)
                     /gene="zraS"
                     /locus_tag="OPV72_002361"
     CDS             complement(4544..5941)
                     /gene="zraS"
                     /locus_tag="OPV72_002361"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     ZraS"
                     /protein_id="HCR9914638.1"
                     /translation="MSFIRLHKDAAAMWLSRLLPAAIFILVGLFSIMVIRDYGRESAA
                     ARQTLLEKGNVLIRALESGTRVGMGMRMHHAQQQTLLEEMAGQPGVLWFAVTDAQGVI
                     ITHSNPGMVGKSLYSPSEMHQLNPGPQECWRRVDVAANGETVPALEIYRQFQPLFGMR
                     GHGMRGHGMARSANDDEPAKQTIFIAFDASELAATQAREWRNTLIVLSALAAVLLATL
                     LAFFWYQRYQRSHRELLDAMKRKEKLVAMGHLAAGVAHEIRNPLSSIKGLAKYFAERT
                     PAGGESHELAQVMAKEADRLNRVVSELLELVKPAHLTLQAVNLNDIITHSLNLVSQDA
                     QSREIQLRFTANETLKRIQADPDRLTQVLLNLYLNAIHAIGRQGTITVEAKESGTDRV
                     IITVTDSGKGIAPDQLEAIFTPYFTTKADGTGLGLAVVQNIIEQHGGAIKVKSIEGKG
                     AVFTIWLPVIARQQD"
     gene            6195..6650
                     /gene="zraP"
                     /locus_tag="OPV72_002362"
     CDS             6195..6650
                     /gene="zraP"
                     /locus_tag="OPV72_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc resistance sensor/chaperone ZraP"
                     /protein_id="HCR9914639.1"
                     /translation="MKRNNKSAIALIALSLLALSSGAAFAGHHWGNNDGMWQQGGSPL
                     TTEQQATAQKIYDDYYTQTSALRQQLISKRYEYNALLTASSPDTAKINAVAKEMESLG
                     QKLDEQRVKRDVAMAQAGIPRGAGMGYGGCGGYGGGYHRGGGHMGMGNW"
     gene            complement(6692..7384)
                     /locus_tag="OPV72_002363"
     CDS             complement(6692..7384)
                     /locus_tag="OPV72_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1481 domain-containing protein"
                     /protein_id="HCR9914640.1"
                     /translation="MNSFIEGACQPLLSVWRRAFLFSGALLLTACSHNASPPPFTASG
                     FAGDHGAVRIWRKDTNDEVHLLSVFSPWHSGSTTTSEYRWQGDTLSLIELNIYSKPPE
                     HIRARFDAHGELSFMQREVGGQKQQLSNDQIALYRYRAEQIRQTSDALRLGRVILRQG
                     RWHADHTVTTCEGETLKPDLDSWAISHIERRQNHSSVEVSVAWLEAPEGSQLLLVANS
                     DFCHWQPQAKTF"
     gene            complement(7396..7668)
                     /gene="hupA"
                     /locus_tag="OPV72_002364"
     CDS             complement(7396..7668)
                     /gene="hupA"
                     /locus_tag="OPV72_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017460010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein HU-alpha"
                     /protein_id="HCR9914641.1"
                     /translation="MNKTQLIDVIADKAELSKTQAKAALESTLAAITESLKEGDAVQL
                     VGFGTFKVNHRAERTGRNPQTGKEIKIAAANVPAFVSGKALKDAVK"
     gene            complement(7855..8445)
                     /locus_tag="OPV72_002365"
     CDS             complement(7855..8445)
                     /locus_tag="OPV72_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjaG family protein"
                     /protein_id="HCR9914642.1"
                     /translation="MLQNPIHLRLERLESWQHVTFMACLCERMYPNYAMFCKQTEFGD
                     GQIYRRILDLIWETLTVKDAKVNFDSQLEKFEEAIPAADDYDLYGVYPAIDACVALSE
                     LMHSRLSGETLEHAIEVSKTSITTVAMLEMTQAGREMTDEELKTNPAVEQEWDIQWEI
                     FRLLADCEERDIELIKGLRADLREAGESNIGINFQQ"
     gene            complement(8487..9158)
                     /gene="nfi"
                     /locus_tag="OPV72_002366"
     CDS             complement(8487..9158)
                     /gene="nfi"
                     /locus_tag="OPV72_002366"
                     /EC_number="3.1.21.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease V"
                     /protein_id="HCR9914643.1"
                     /translation="MDLASLRAQQIELASSVCREDRLDKDPPAFIGGADVGFEQGGEV
                     TRAAMVLLKYPSLELVEYKVARIATTMPYIPGFLSFREYPALLAAWEQLSQKPDLLFV
                     DGHGISHPRRLGVASHFGLLVDVPTIGVAKKRLCGKFEPLSAEPGALSPLMDKGEQLA
                     WVWRSKARCNPLFIATGHRVSTDSALAWVQRCMKGYRLPEPTRWADAVASGRPAFVRW
                     QEIQR"
     gene            complement(9168..10232)
                     /gene="hemE"
                     /locus_tag="OPV72_002367"
     CDS             complement(9168..10232)
                     /gene="hemE"
                     /locus_tag="OPV72_002367"
                     /EC_number="4.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen decarboxylase"
                     /protein_id="HCR9914644.1"
                     /translation="MTELKNDRYLRALLRQPVDVTPVWMMRQAGRYLPEYKATRAQAG
                     DFMSLCKNAELACEVTLQPLRRYPLDAAILFSDILTIPDAMGLGLYFEAGEGPRFTAP
                     VTCKADVDKLPIPDPEDELGYVMNAVRTIRRELKGEVPLIGFSGSPWTLATYMVEGGS
                     SKAFTVIKKMMYADPQALHLLLDKLAKSVTLYLNAQIKAGAQSVMIFDTWGGVLTGRD
                     YQQFSLYYMHKIVDGLLRENDGRRVPVTLFTKGGGQWLEAMAETGCDALGLDWTTDIA
                     DARRRVGHKVALQGNMDPSMLYAPPARIEDEVATILAGFGQGEGHVFNLGHGIHQDVP
                     PEHAGAFVEAVHRLSAQYHN"
     gene            complement(10273..11046)
                     /gene="nudC"
                     /locus_tag="OPV72_002368"
     CDS             complement(10273..11046)
                     /gene="nudC"
                     /locus_tag="OPV72_002368"
                     /EC_number="3.6.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) diphosphatase"
                     /protein_id="HCR9914645.1"
                     /translation="MDRIIEKLESGWWIVSHEQKLWLPYGELPHGLAANFDLVGQRAL
                     RIGEWQGEPVWLVLQHRRHDMGSVRQVIDQDAGLFQLAGRGVQLAEFYRSHKFCGYCG
                     HPMHPSKTEWAMLCSHCRDRYYPQIAPCIIVAIRREDSILLARHVRHRNGVHTVLAGF
                     VEVGETLEQAVAREVMEESGIKVKNLRYVTSQPWPFPQSLMTAFMAEYDSGEIVIDPK
                     ELLEANWYRYDDLPLLPPPGTVARRLIEDTVAMCRAEYD"
     gene            11139..11627
                     /gene="rsd"
                     /locus_tag="OPV72_002369"
     CDS             11139..11627
                     /gene="rsd"
                     /locus_tag="OPV72_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma D regulator"
                     /protein_id="HCR9914646.1"
                     /translation="MLNQLENLMERVGGSNKLVDRWLDVRKHLLVAYYNLVGIKPGKE
                     SYMRLNEKALDDFCQSLVDYLSAGHFSIYERILHKLEGNGQLLHAAKIWPLLEDNTQR
                     IMDYYDTSLETAIDHDNCLEFQQALSDIGEALEARFVLEDKLIMLVFDAMHDGARVKR
                     PA"
     regulatory      11742..11905
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            11991..13886
                     /gene="thiC"
                     /locus_tag="OPV72_002370"
     CDS             11991..13886
                     /gene="thiC"
                     /locus_tag="OPV72_002370"
                     /EC_number="4.1.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HCR9914647.1"
                     /translation="MSTTTLTRREQRAKAQHFIDTLEGTAFPNSKRIYVTGSQHDIRV
                     PMREIQLSPTLIGGSKDNPQFEENEAVPVYDTSGPYGDPEVAINVQQGLAKLRQPWID
                     ARNDSEELDDRSSAYTRERLADDGLDDLRFTGLLTPKRAKAGKRVTQLHYARQGIVTP
                     EMEFIAIRENMGRERIRSEVLRHQHPGMNFGARLPENITPEFVRDEVAAGRAIIPANI
                     NHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYI
                     HETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHA
                     GVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHKENFLFEHFREICEICSAYDVSLSL
                     GDGLRPGSIQDANDEAQFSELHTLGELTNIAWEYDVQVMIEGPGHVPMHMIQRNMTEE
                     LESCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKE
                     DVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYH
                     DETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQAIEVGMADMSENFRAKGGEI
                     YLKREEA"
     gene            13886..14521
                     /gene="thiE"
                     /locus_tag="OPV72_002371"
     CDS             13886..14521
                     /gene="thiE"
                     /locus_tag="OPV72_002371"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HCR9914648.1"
                     /translation="MYQPDFPTVPFRLGLYPVVDSVAWIERLLEAGVRTIQLRIKDKR
                     DEEVEADVIAAIALGRCYDARLFINDYWRLAIKHNAYGVHLGQEDLETTDLKAIQAAG
                     LRLGVSTHDDMEIDIALAAKPSYIALGHVFPTQTKQMPSAPQGLAQLARHIERLADYP
                     TVAIGGISLERAPAVLATGVGSIAVVSAITQAADWRAATAQLLAIAGVGDE"
     gene            14514..15272
                     /locus_tag="OPV72_002372"
     CDS             14514..15272
                     /locus_tag="OPV72_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HesA/MoeB/ThiF family protein"
                     /protein_id="HCR9914649.1"
                     /translation="MNDRDFMRYSRQILLGDIAIEGQQKLLNSHVLIVGLGGLGSPAA
                     LYLAGAGIGTLTLADDDDVHLSNLQRQILFTTDDIARSKSQVAQQHLTRLNPDIELVS
                     LQQRLKGDALRHAVARADVVLDCTDNMATRQEINAACVALNTPLITASAVGFGGQVMV
                     LTPPWEQGCYRCLWPDDVEPERNCRTAGIVGPVVGVMGTLQALEAIKLLSGIETPSGE
                     LRLFDGKTSQWRSLALRRASGCPVCGGRHANSIQ"
     gene            15253..15453
                     /gene="thiS"
                     /locus_tag="OPV72_002373"
     CDS             15253..15453
                     /gene="thiS"
                     /locus_tag="OPV72_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="HCR9914650.1"
                     /translation="MQIQFNDEPMQCAEGQTVSSLLATLNQLQPGAALALNQQILPRE
                     QWRQHIVQEGDQILLFQVIAGG"
     gene            15455..16225
                     /gene="thiG"
                     /locus_tag="OPV72_002374"
     CDS             15455..16225
                     /gene="thiG"
                     /locus_tag="OPV72_002374"
                     /EC_number="2.8.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="HCR9914651.1"
                     /translation="MLRIADKTFDSHLFTGTGKFASSQLMVEAIRASGSQLVTLAMKR
                     VDLRQHNDAILAPLIEAGVTLLPNTSGAKTAEEAIFAAQLALEALGTHWLKLEIHPDA
                     RWLLPDPIETLKAAEALVKQGFVVLPYCGADPVLCKRLEEVGCAAVMPLGAPIGSNQG
                     LETKAMLEIIIQQATVPVVVDAGIGVPSHAAQALEMGADAVLVNTAIAVADDPVMMAT
                     AFRLAVEAGLLARQAVPGNRSTYASATSPLTGFLEALA"
     gene            16222..17355
                     /gene="thiH"
                     /locus_tag="OPV72_002375"
     CDS             16222..17355
                     /gene="thiH"
                     /locus_tag="OPV72_002375"
                     /EC_number="4.1.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminoacetate synthase ThiH"
                     /protein_id="HCR9914652.1"
                     /translation="MKAFTDRWRQLEWDDIRLRINGKTAADVERALNASRLNREDMMA
                     LLSPAAADYLEPMAQRAQRLTRQRFGNTVSFYVPLYLSNLCANDCTYCGFSMSNRIKR
                     KTLDEVDIQRECDAIRKLGFEHLLLVTGEHQAKVGMDYFRRHLPTIRRQFSSLQMEVQ
                     PLSQENYAELKTLGIDGVMVYQETYHEAIYAQHHLKGKKQDFFWRLETPDRLGRAGID
                     KIGLGALIGLSDNWRVDCYMVAEHLLWMQKHYWQSRYSVSFPRLRPCTGGVEPASVMD
                     EKQLVQTICAFRLLAPEIELSLSTRESPWFRDHVIPLAINNVSAFSKTQPGGYADDHP
                     ELEQFSPHDDRRPEVVASALSAQGLQPVWKDWDSWLGRASQMR"
     gene            complement(17436..17651)
                     /locus_tag="OPV72_002376"
     CDS             complement(17436..17651)
                     /locus_tag="OPV72_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017466138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914653.1"
                     /translation="MDKNDQQTRLEEGPPAKLQSGTLPENFKFTAISIIQWPAPGRQL
                     LMKGRRLGKNEEGIICPGQLPLLTMTK"
BASE COUNT         4075 a         5143 c         4856 g         3882 t
ORIGIN      
        1 ttatctgctg accgcaatag aaaaattgca gaaaaatgac tgtttgctgc attccccagc
       61 aaaacccttg gttataccca tttacgcaca gacttatcca caaaatgcgc gttcatttcc
      121 tcgatcttct cactctgcaa acgatctttc agggataaaa gcggggccag aatttaaaga
      181 gaaaaattcg cgagcgttgc gcaaacgttt tcgttacaat gtcgccgcaa aatgagaatg
      241 ccccataagg agcgttagct gagtttttca cgaaaaattc agctaacgct ctctataatc
      301 gtcaaatcca ggggatttac catgcaacaa cgtcgtccag tccgccgcgc tttgctcagt
      361 gtttctgaca aggccggtat catcgaattc gcccaggcac tttccgcacg cggtgtggag
      421 ctgctgtcta cggggggcac cgcccgcctg ttagcagaaa aaggcctgcc ggtgaccgaa
      481 gtttccgatt acaccggttt cccggaaatg atggatggac gcgtaaagac cctgcatcca
      541 aaagtacacg gtggcatcct cggtcgtcgc ggtcaggacg atgccattat ggaacagcac
      601 cacatcgccc ctatcgatat ggttgtcgtt aacctatatc cgttcgccga aaccgtggca
      661 cgcgaaggct gctcgctggc agatgcagta gagaacattg atatcggcgg cccgaccatg
      721 gtgcgctctg ctgctaagaa ccataaagac gtcgccatcg tggtgaagag cagcgactac
      781 gacgccatta ttaaagagat ggatgctaac gaaggttctc tgaccctcga cacccgtttc
      841 gatctcgcga ttaaagcctt cgaacacacc gccgcctacg acagcatgat cgccaactac
      901 ttcggcagca tggttccggc ctaccacggt gaaagcaaag aagccgccgg tcgcttcccg
      961 cgtacgctga acctgaactt cattaagaag caggatatgc gctacggcga gaacagccac
     1021 cagcaggctg ccttctatat agaagagaat gtgaaagaag catccgttgc caccgcacag
     1081 cagattcagg gcaaagcgct ctcttataac aatatcgccg ataccgatgc ggcgctggaa
     1141 tgcgtgaaag agttcaacga gccagcctgc gtgatcgtca agcacgccaa cccgtgcggc
     1201 gtggcggtaa gtacctcgat tctcgatgct tatgaccgtg cgtataaaac agacccgacc
     1261 tccgcgttcg gcggcattat cgccttcaac cgcgagctgg atgccgaaac cgcgcaggcc
     1321 atcatctccc gtcagttcgt ggaagtgctc atcgccccat ccgcaagcga agaagcgctg
     1381 aaaatcacct cagccaagca gaacgtccgt gttctgacct gcggccaatg ggcaagccgc
     1441 gttccgggcc tggatttcaa acgcgttaac ggcggtctgc tggttcagga cagggatctg
     1501 ggtatggtga gcgaagctga actgcgcgtg gtgtccaaac gccagccgac cgagcaggaa
     1561 ctgcgcgatg cgctgttctg ctggaaggta gccaagttcg tgaaatccaa cgccattgtg
     1621 tatgccaaag agaacatgac tatcggcata ggcgcaggcc agatgagccg cgtgtactcc
     1681 gcgaaaatcg ctggcattaa agcggctgac gaaggtctgg aagtgaaagg ctctgctatg
     1741 gcttccgacg cgttcttccc gttccgtgat ggcattgatg ccgctgccgc tgtcggcgtg
     1801 agctgcgtta tccagcctgg cggttctatc cgtgatgatg aagtcattgc cgccgccgac
     1861 gaacacggca ttgcgatgat cttcaccgac atgcgccact tccgccatta attcagggag
     1921 cagacgatga aagttttagt cattggtaac ggcgggcgcg aacatgcgct ggcctggaaa
     1981 gccgcacagt cgccgctggt tgataccgtt tttgtcgcac cgggtaacgc cggtaccgcg
     2041 ctggagcccg cgttgcagaa cgtggctatc ggcgtcaccg atattccggc gctgctgagc
     2101 tttgcccaga acgagaagat tgatctgacc atcgtcggtc cggaagcgcc gctggtgatc
     2161 ggcgtggtcg atgcgttccg cgcggcgggt ctgaagatct ttggcccaac cgaaggagcc
     2221 gcgcaactgg aaggctccaa agcgttcacc aaagatttcc tcgcccgtca tcagattccg
     2281 acggcggaat accagaattt caccgagatt gagcctgcct tggcttatct gcgtgagaag
     2341 ggcgcgccga tcgtcatcaa ggccgatggt ctggctgcgg gcaaaggcgt catcgtggcg
     2401 atgacgctgg aagaagccga agccgccgtt catgacatgc tggcaggcaa cgcctttggc
     2461 gacgcgggcc accgtatcgt gattgaagag ttcctcgacg gcgaagaagc gagctttatc
     2521 gtgatggtcg acggcgagca cgtgctgccg atggccacca gccaggatca caaacgcgta
     2581 ggcaacggcg ataccggccc gaatactggc ggcatgggtg cttactcccc ggcgccggtg
     2641 gtgactgatg aagtgcacca gcgcaccatg gaacgcatca tctggccaac cgtgaaaggc
     2701 atggcagcag aaggtaacac gtacaccggc ttcctgtatg cgggtctgat gatcgacaag
     2761 cagggcaacc cgaaagttat cgagttcaac tgccgcttcg gcgatccgga aacccagccg
     2821 atcatgctgc gcatgaaatc ggatctggtg gatctttgcc tggccgcctg tgacggcaag
     2881 ctggatgaga aaacctccga gtgggacgaa cgcgcttcat taggcgtggt gatcgccgcg
     2941 ggcggttatc cgggcagcta cagcaccggc gacgagatcc acggtctgcc gctggaagaa
     3001 gtggctgacg gtaaggtttt ccacgcgggc accaaactcg ccgatgacga ccgcgtgttg
     3061 accagcggcg gtcgcgtact gtgcgccacc gcgctgggcc acaccgtggc cgaagcgcag
     3121 aaacgcgctt acgccctgat gaccgacatc cgctgggacg gcagcttcag ccgtaacgac
     3181 attggctggc gcgccattga gcgtgagcaa aactaacggc tgagtttagc cagcagcgtt
     3241 ttgcgcgtaa tgcccaattg acgggcggct tccgttttgt tgccgcccgt tttttccagc
     3301 gccgccagaa tcacctcttt ctccacatcg accaacggtt ggatttcggc gctgttttcc
     3361 gcttttatcg gcgtcgcggc aatagcgaga ggcaattcgc gttcagaaat gtattctccc
     3421 gtcagcaaca ccaccgctcg ttcgatagcg ttttccagct cacggatatt acccggccag
     3481 tcgtagtgga tcagcagatc catcgcctgc ggcgtaaacc ccttcaccgc ttttcggtta
     3541 cgttcggcaa aacgccgcag aaaatggtct gccagtagcg gaatatcttc ccgacgctgg
     3601 cgcaaagaag gcatttcaat cgccaccaca ttcaggcggt aatagagatc ctggcgaaag
     3661 cgaccggcac tcacctcttc cgccaggtcg cggtgggtag cggcaattaa ccaaacatcc
     3721 acagatatcg tctggttact tcccacgcgt tgcacttcgc gctcctgaat cgcccgcagc
     3781 aaacgtacct gcattaacgg cgagatatcg ccgatttcat caagaaacaa tgtcccgccg
     3841 tcagcttcga caaagcgtcc ctcccgacgt ttatccgcgc cggtaaacgc gcctttttcg
     3901 tgtccgaaca gctcagactc cagcagcgat tcattaagcg ccgcgcagtt gagcgtgacc
     3961 agcggtttat cgctcctggc gctacaggcg tgcagcgccc gcgccaccag ctctttaccc
     4021 gtgccggagt ctccgtgaat caataccgtg gcgtctgatg gtgcgaccat cgcgatttca
     4081 ttcaataaat gttgcatcgc cgggctgctg ccaatcatgc caaattgcgc agccgacgcc
     4141 gatggcaatt cagcgcccgt ttcccgcgta tgcgccaacg ccttttccag cgtctcctgc
     4201 agacggtcaa aatccagcgg tttaattaaa tagtcgagcg cgccggcttt caacgcctct
     4261 accgccgttt ccacgctgga gaatgccgtc ataatcaaaa tcggaatggc ggggttgagc
     4321 gctttaatct ccttcagcgt ggcgataccg tccatctccg ccatacgcac atcgcacagt
     4381 accagatcaa agactttctc acgcacctga gccaacgcat catgcccact gtaggccaga
     4441 gcgacgttat agccccagcc ccgaagcagc gcctgtaaaa tcgtgcagtg gcttacatca
     4501 tcatccacaa ccagaatatc gatttttccg cgtatcaccc ttgttaatcc tgttgtctcg
     4561 ctatcactgg caaccagata gtaaagaccg cgcctttacc ctcaatactt ttcaccttaa
     4621 tcgcgccgcc atgctgttcg atgatatttt gcaccaccgc cagccccagg cctgtcccgt
     4681 cagctttggt cgtaaaataa ggtgtaaaaa tcgcctccag ctgatccggg gcaatccctt
     4741 tcccgctatc ggtaacagtg atgataacgc ggtcggtccc actttctttt gcctctacgg
     4801 taatcgttcc ctggcggcca atcgcatgaa tagcgttcag gtacaaattc aacagcacct
     4861 gagtcagcct gtccgggtca gcctgaatac gcttaagcgt ctcattcgcc gtgaatctca
     4921 actgaatctc tctgctttgg gcatcctgac tgaccagatt cagggagtga gtaataatat
     4981 cattgaggtt aaccgcctgg agcgtcagat gcgcgggctt taccagttcg agcaattcgc
     5041 ttaccacccg gttcaaacgg tcggcctctt tggccatcac ctgcgccagt tcatgcgact
     5101 cgccgccggc aggcgtgcgc tcggcaaagt atttcgccag ccctttgatg gacgagagcg
     5161 ggttacgaat ttcgtgcgcg acgcccgccg ccagatgccc catcgccacc agcttttctt
     5221 tacgcttcat tgcatcaagc agttctctgt gcgagcgctg ataacgctga taccaaaaaa
     5281 acgccagtaa cgttgccaac agcaccgccg ctaacgcaga caaaacaatc agcgtattac
     5341 gccactccct tgcctgagtc gcggccagct cgctggcgtc aaaggcaata aaaatagttt
     5401 gtttcgctgg ttcgtcgtca ttggcgctac gcgccatgcc gtgccccctc ataccgtgac
     5461 ctctcatacc gaaaagcggc tggaactgac ggtaaatttc cagcgcaggc accgtctcgc
     5521 cgttagcagc aacgtcgaca cgccgccaac actcctgcgg cccggggttt agttgatgca
     5581 tttcagatgg ggaatagagc gacttgccca ccatgccagg gttgctatga gtgatgatta
     5641 ccccctgtgc atccgttaca gcgaaccaca acacgcctgg ctgacccgcc atctcttcca
     5701 gcaatgtctg ctgctgcgcg tgatgcatcc gcattcccat acctactcgc gtgccggact
     5761 ccagagcgcg aatgagtaca tttccctttt ccagcagcgt ctgcctggcg gcagcgctct
     5821 cacggccata gtcgcgaatg accataatgg aaaatagccc caccagaatg aagatcgccg
     5881 caggtaacag ccgactcaac cacattgcag cggcatcttt atgtaatcgt ataaaactca
     5941 caggcttccc cggctcgttt ttattttcct tacttaagca gagatcatgc cattcttcgc
     6001 tccgcataac cgcgcgttgt cgcacaccct ttcggatacg gatgggtaaa aatgactcgc
     6061 caggcgggtc atgcgagtca tttttactcg ctttttgccg cctgaagcgg gttaactcgc
     6121 tgcccgacaa ggaatagtta cctggcacgg aagatgcaag agagaggata agatgagcaa
     6181 caggagaacg caaaatgaaa cggaacaata aatcagctat cgcgctaatc gccctctctc
     6241 ttttggccct gagctccggc gccgccttcg ccgggcatca ctggggcaac aatgacggta
     6301 tgtggcaaca gggaggtagc ccgttaacca cggaacagca ggcgacggcg cagaagattt
     6361 atgatgatta ctatacgcag accagcgcgc tgcgccagca actgatatcc aaacgttatg
     6421 aatacaacgc gctactgacc gccagttcgc cggatactgc gaaaattaac gcggttgcca
     6481 aagagatgga gtcattaggc cagaagttag atgagcaacg cgtgaaacgg gatgtcgcga
     6541 tggcgcaggc tggcatacca cgcggcgcag gaatgggcta tggcggttgc ggcggctatg
     6601 gcggcggtta tcatcgcggc ggcggtcata tgggtatggg aaactggtaa agcatgtttg
     6661 ccgaatggcg gcttcgccat tcggtattcc atcaaaaggt tttcgcttgc ggctgccagt
     6721 gacagaaatc tgaattcgcc accagcaaaa gttgcgatcc ttccggcgcc tccagccatg
     6781 ctacgctcac ctctaccgat gagtggttct ggcggcgctc aatgtggctt attgcccaag
     6841 aatccagatc cggtttcagc gtttcacctt cacaggtggt taccgtatgg tcggcgtgcc
     6901 agcgtccctg gcgtagtatg acccgcccca ggcgcaatgc gtcgctggtc tgacggattt
     6961 gttcggcacg atagcgatac aaggcaatct gatcgttgga aagctgctgc ttctgccccc
     7021 cgacttcacg ctgcataaaa ctgagttcgc catgagcgtc gaaacgcgcg cgaatatgtt
     7081 ctggcggttt gctgtaaata ttgagttcaa taagcgaaag cgtatcaccc tgccaacgat
     7141 attcgctggt cgtcgtgcta ccactatgcc acgggctaaa aacagaaagc agatggactt
     7201 catcgttcgt atctttacgc cagatacgca ccgcgccgtg atcgccggca aagccgctgg
     7261 cagtaaacgg aggcggtgaa gcgttatgac tgcaggcagt cagcaacagc gcgccagaaa
     7321 acagaaacgc gcgacgccag acggacaaaa ggggctgaca agccccttcg ataaaactgt
     7381 tcacagttac gcgtcttact taactgcgtc tttcagagct ttaccagaaa caaacgccgg
     7441 tacgttagcg gcggcgattt tgatttcttt accggtctgt gggttacggc cagtgcgctc
     7501 agcacggtgg ttcactttga aggtaccgaa accaaccagt tgtacagcat cgccttcttt
     7561 cagagactca gtaatagcag ccagagtgga ttccagagca gctttagcct gggttttgga
     7621 cagttctgct ttgtctgcaa ttacatcaat cagttgagtc ttgttcataa gttatcctta
     7681 caatgtgttt atcgcttgct aagcatcgag tgcgacggaa atgccagaaa agcactctcc
     7741 tgcatacacg caccgatagc cacttttttt cgcctcccaa atgtagacca gacggggggc
     7801 ataagggaag ccttatggca cgacaaatca gacgttaaat cacgttttct ggtgtcattg
     7861 ctgaaaattt ataccgatat tgctctcgcc agcctcgcgc aggtctgccc tgagcccttt
     7921 tatcagttca atatcacgtt cttcgcagtc ggctaaaagt cggaatattt cccactgaat
     7981 atcccattcc tgttcaacgg cagggttcgt tttgagctcc tcatcggtca tttcccgacc
     8041 agcctgagtc atttccaaca tcgctaccgt agtaatggaa gtcttactaa cctcaatagc
     8101 atgttccagc gtttcgccgc taagacgaga atgcattaat tcgcttaatg cgacgcaggc
     8161 atcaatcgcc gggtaaacgc cgtacaaatc atagtcgtcg gctgccggaa ttgcctcttc
     8221 aaacttctcc agttggctat cgaaattgac ctttgcatct ttcaccgtca gggtttccca
     8281 gatcagatcc agaatgcgac ggtagatctg tccgtcgccg aattccgtct gcttgcaaaa
     8341 catggcgtag ttcgggtaca tgcgctcgca caagcaggcc ataaaggtaa cgtgctgcca
     8401 actttccagc cgctccagcc gcaaatgaat cgggttttgt aacatgatgg aatctcgaat
     8461 cggaaattag cggcagttta cctgaatcag cgctgaattt cttgccaacg aacaaacgcc
     8521 ggacgcccgg aagcgacggc atccgcccag cgcgtcggct ccggcaggcg ataccctttc
     8581 atacagcgct gtacccacgc cagcgcgctg tcagtactga cccggtgccc tgtcgcgata
     8641 aacagcggat tacagcgcgc cttgctgcgc catacccacg ccagttgctc gcctttatcc
     8701 attaaggggc taagtgcgcc aggttcggcg gaaagtggtt caaatttacc gcatagccgt
     8761 tttttcgcca cgccgatggt cggcacgtcc accaacagtc caaaatgact ggcgacgcca
     8821 agccgacgcg gatgcgaaat accgtgaccg tccacaaaca gcaaatcggg cttttgcgag
     8881 agctgttccc acgctgccag cagcgcagga tattcacgaa aagagagaaa gccggggata
     8941 tacggcatgg tggtggcaat acgcgccacc ttgtactcta ctagctcaag cgacggatat
     9001 ttcagcaata ccatcgccgc ccgcgtcacc tcgccgccct gctcaaaacc gacgtccgcc
     9061 ccgccgataa acgctggcgg atctttgtcc aggcgatctt cgcggcaaac tgatgaagca
     9121 agttctatct gttgagcgcg tagcgacgcg agatccatac taactcctta gttgtgatac
     9181 tgcgcagaaa gtcggtgcac tgcctccaca aatgcgccag catgttctgg cggcacatcc
     9241 tgatggatgc catgtccaag gttaaagacg tgcccttctc cctgaccgaa accagcaagt
     9301 atagtcgcta cctcgtcttc gatccgtgcc ggcggcgcat acagcatgga cggatccata
     9361 ttgccctgca gcgccacttt atggccaacg cgacggcgcg catcggcgat atctgtcgtc
     9421 cagtcgagac ccagcgcatc gcagccggtt tccgccatcg cctccagcca ctgaccgcca
     9481 cctttagtga acagcgttac cggcacgcgg cgaccgtcgt tttcacgcag caggccatcg
     9541 acgattttat gcatgtagta gagggagaac tgctggtaat cgcggccagt cagcacgccg
     9601 ccccaggtgt cgaaaatcat caccgactgc gcgcccgctt tgatttgcgc gttgaggtac
     9661 agcgtgacgc ttttcgccaa cttatccagc agcagatgca acgcctgcgg gtcagcgtac
     9721 atcatctttt taatcaccgt gaaggctttg ctactgccgc cttccaccat gtaagtcgcc
     9781 agcgtccacg ggctgccgga gaagccgatc agcggaacct cgccttttag ttcgcggcga
     9841 atcgtgcgta ccgcattcat cacgtagccc agttcatcct ccggatcggg aatgggcagc
     9901 ttatcgacat cggctttgca ggtgacaggg gccgtaaagc gcgggccttc cccggcttca
     9961 aaatagagcc ccaggcccat cgcgtccgga atcgtcagga tatccgagaa aaggatcgcc
    10021 gcatcaagcg gataacggcg cagcggctgt aaagtgactt cgcaggccag ttcggcattt
    10081 ttgcacagcg acataaaatc gcccgcctga gcgcgagtgg ctttgtactc cggtagataa
    10141 cggcccgcct ggcgcatcat ccacactggc gtaacatcaa cgggctggcg cagcagcgca
    10201 cgtagataac gatcgttttt gagttcggtc atttttacat tcctttagcg ttgatgcgcc
    10261 cagtgtaaca tgtcagtcgt attcagcccg acacattgcc accgtatctt cgatcaaacg
    10321 gcgcgcgacg gtgcccggcg gcggcagtag cggcagatcg tcataacggt accaatttgc
    10381 ttccaacagt tctttcgggt cgatgacaat ctcgccgctg tcatactctg ccataaacgc
    10441 cgtcatcagc gactgtggga acggccacgg ctgcgaggtc acgtagcgca gatttttcac
    10501 cttgatcccg ctttcctcca tgacttcgcg cgccacagcc tgctccaggg tttcgccgac
    10561 ttcaacaaac ccggccagta ccgtatgcac gccgttgcgg tggcgaacgt gccgggcaag
    10621 tagaatagaa tcctcacggc gaatggcaac aataatgcag ggggcgattt gcgggtagta
    10681 acgatcgcgg caatggctgc acagcatcgc ccattcggtt ttactcgggt gcatagggtg
    10741 cccgcaatag ccgcaaaatt tatgcgaacg ataaaactcc gccaactgta cgccacgtcc
    10801 cgccagttga aacagcccgg catcctgatc gataacctgg cgaaccgatc ccatatcatg
    10861 acgtcgatgc tgtaacacca gccagacggg ctcgccttgc cattcaccta tccggagtgc
    10921 gcgctgcccc acaagatcga aatttgccgc cagcccgtgt ggtaattccc catacggcaa
    10981 ccataatttt tgttcatggc tgacgatcca ccagccactc tctaattttt caattatacg
    11041 atccatagct attgcactac ctttgcttca ctggcatgtt gttaacatta tttttacatt
    11101 catggcgagc agcctttatc taacttgcgg agacaatcat gctaaaccag ctggaaaacc
    11161 tgatggagcg cgttggcgga agcaacaaac tggtcgatcg ctggctggat gtacgtaagc
    11221 acctgctcgt ggcttactac aatctggttg gcattaagcc tggcaaagaa tcgtacatgc
    11281 ggctgaatga aaaagcgctg gatgattttt gtcagagcct ggtcgattac ctttccgccg
    11341 ggcacttcag tatttatgaa cgtattctcc ataaattgga aggaaacggt cagcttttac
    11401 atgcggcaaa aatttggccg ctgctggaag ataatacgca gcgcattatg gattattacg
    11461 acaccagcct ggaaactgcc atcgatcacg ataattgtct cgaatttcaa caagctctgt
    11521 cagatatcgg cgaagcgctg gaagcccgct ttgtgctgga agacaagctg attatgctgg
    11581 tgtttgacgc gatgcacgac ggcgccagag tcaaacgtcc cgcttgagtt ctgcgcgagt
    11641 aacaggtagt ttacttcagc cccctcttcg gaggggcggt tatcttgtcg gagtgctaat
    11701 tttccacaaa agcgttcgtg atgcgtcaag gcggcaagtc ggtgaatctc caggagctta
    11761 cataagtaag tgactggagt gagcggacga agccaacgaa gaggcagcgc gaaggatgaa
    11821 gtggaaaagg ctgagaccgt taattcggga tccgcggaac ctgatcaggt taatacctgc
    11881 gaagggaaca agagtaattc tgctttatgc tgctgccttt acgggcggcg cacatccatt
    11941 actccatccg tcgtctgaca agccacgtcc ttaatttttt ggaatgagct atgtctacaa
    12001 caacgttaac ccgccgcgag cagcgcgcta aagcccagca ttttatcgat acgctggaag
    12061 ggactgcctt tcccaactcg aaacgcatct acgtgaccgg ttcgcagcat gatattcgcg
    12121 taccgatgcg cgaaattcaa cttagcccta cgctcatcgg cggcagtaaa gacaacccgc
    12181 agtttgaaga gaacgaagcc gtaccggtat acgacacctc cggcccctat ggcgatcctg
    12241 aagtggcgat taacgtccag cagggtctgg cgaaactgcg ccagccgtgg attgacgcac
    12301 gtaacgatag cgaagaatta gacgaccgta gctcggctta caccagagaa cgtctggccg
    12361 acgatggcct ggacgatctg cgttttaccg gcctgctgac gccgaaacgc gctaaagcgg
    12421 gcaagcgcgt cacccagtta cactacgccc gccaggggat cgtcactccc gaaatggagt
    12481 tcatcgccat ccgtgaaaac atgggccgcg agcgcattcg cagtgaagtg ctgcgccacc
    12541 agcatccggg catgaacttt ggcgcgcgcc tgccggaaaa cattacgccg gaattcgtgc
    12601 gtgatgaagt cgccgcgggc cgcgcgatta ttcccgccaa catcaaccac ccggaatcgg
    12661 agccgatgat tatcggccgc aacttcctgg tcaaagtgaa tgccaacatc ggtaactcgg
    12721 cggtcacctc ctccatcgaa gaagaggtcg agaagctggt gtggtcaacc cgctggggcg
    12781 cggacacggt gatggacctc tccaccggtc gctatattca cgaaacccgc gaatggatcc
    12841 tgcgtaacag cccggtaccg atcggcaccg tcccgatcta ccaggcgctg gaaaaggtca
    12901 acgggatcgc cgaagatctc acctgggaag cgttccgcga cacgctgctg gagcaggccg
    12961 aacagggcgt cgactacttc accatccacg ccggcgtgct gctgcgctac gtgccgatga
    13021 ccgccaaacg cctgaccggt attgtctcgc gcggcggttc gatcatggca aagtggtgtc
    13081 tctcccatca caaagagaac ttcctgttcg aacatttccg cgagatttgt gaaatctgct
    13141 ccgcctacga cgtttccctg tcgctgggcg acggcctgcg ccccggctcc attcaggacg
    13201 ccaacgacga agcgcagttc tccgagctgc atacgctggg cgagctgacc aatatcgcct
    13261 gggaatacga cgtgcaggtg atgattgaag gcccgggcca cgtgccgatg catatgattc
    13321 agcgcaacat gaccgaagag ctggagagct gccacgaagc gccgttctac accttagggc
    13381 cgttgaccac cgatatcgcg ccgggctatg accacttcac ctctggcatt ggcgcggcga
    13441 tgatcggctg gtttggctgc gcgatgctgt gttacgtgac gccgaaagag catctcggcc
    13501 tgccgaacaa agaagatgtg aagcaggggc tgatcaccta caaaatcgcc gcccacgccg
    13561 cggatttagc caaaggacat ccgggcgcgc agatccgcga taacgccatg tcgaaagcgc
    13621 gctttgaatt ccgctgggaa gatcagttta acctcgcgct cgacccgttc accgcccgcg
    13681 cttatcacga tgaaaccctg ccgcaggagt ccggtaaggt cgcccacttc tgttccatgt
    13741 gtgggccgaa gttctgctca atgaaaatca gccaggaagt gcgtgattac gccgccgcgc
    13801 aagccattga agtcggcatg gcggatatgt cggagaactt ccgcgccaaa ggcggcgaaa
    13861 tttatctcaa acgggaggaa gcctgatgta tcagcctgat ttcccaaccg tgccgttccg
    13921 cctcgggctt tacccggtgg tggacagcgt tgcatggatt gaacgcctgc tggaggcggg
    13981 cgtgcgcacc atccagttgc gtatcaaaga taagcgcgat gaagaggtgg aagccgacgt
    14041 tatcgccgcc atcgcgctgg ggcgttgtta tgacgcccgc ctgttcatca atgattactg
    14101 gcgtctggca attaagcaca acgcctacgg tgtacatttg ggccaggaag atctcgaaac
    14161 cactgacctg aaggcgattc aggcggcggg gttacgcctg ggcgtatcga cccacgatga
    14221 tatggagata gacatcgcac tcgccgctaa gccttcttat atcgcgctgg gtcatgtatt
    14281 ccccacgcaa accaagcaga tgccttccgc cccacagggg ctggcgcagc tggcgcggca
    14341 tattgaacga ctggcggatt atcccaccgt cgctatcggc ggcatcagcc ttgaacgcgc
    14401 tccggcggta ctagcgaccg gcgtcggcag tattgccgtg gtcagcgcca ttactcaggc
    14461 tgccgactgg cgcgccgcta ccgcgcagtt actggcaatc gcgggagtgg gcgatgaatg
    14521 accgcgattt tatgcgctac agtcggcaaa tcctgctcgg cgatatcgcg attgaaggcc
    14581 agcaaaagct gctcaatagc catgtattga ttgtcggctt aggcggattg ggttcgcctg
    14641 ccgcgctgta tctggcggga gcaggcatcg gcacactgac gctggcggat gatgacgatg
    14701 ttcacttgag caatctccag cggcaaattc tgttcaccac cgacgatatc gcgcgttcga
    14761 aatcccaggt tgcccagcag cacctgacac ggctcaaccc ggatatcgaa ctggtatcac
    14821 tccagcagcg actaaaaggc gatgcgctcc ggcatgcggt agcgcgtgcc gacgtggtgc
    14881 tcgactgtac cgacaacatg gcgacccgtc aggaaattaa cgccgcctgc gtggcactca
    14941 acactccgtt aattaccgcc agcgccgttg gttttggcgg ccaagtgatg gtcctcacgc
    15001 cgccgtggga acaaggctgt taccgctgcc tgtggccaga tgatgtggag cctgaacgca
    15061 actgccgtac cgccggtatc gtcggaccgg ttgttggcgt gatgggcacc ttacaggcgc
    15121 tggaagcgat taaattactc agcggtattg agacgcccag tggagagcta cgcctgtttg
    15181 acggtaaaac cagccagtgg cgcagcctgg cgctgcgtcg tgccagcggc tgtccggtat
    15241 gcggagggcg acatgcaaat tcaattcaat gacgagccga tgcagtgcgc cgaagggcaa
    15301 accgtcagca gcctactcgc tacgcttaat cagcttcaac cgggcgcggc gctggcgctc
    15361 aatcagcaga tcctgccacg cgagcagtgg cggcaacata tcgtgcagga aggcgaccag
    15421 atcctgcttt ttcaggttat tgcaggaggt tgagatgtta cgtattgccg acaaaacgtt
    15481 tgattcacat ctgttcaccg gtaccgggaa gtttgcctca tcgcaactga tggtcgaggc
    15541 aattcgcgct tccggcagcc aactggtgac gctggcgatg aagcgcgtgg acctgcgcca
    15601 gcacaatgat gcgattctgg cgccgctgat tgaagcgggc gtcacgctgc tgcccaatac
    15661 ctccggggcg aaaaccgccg aagaggcgat cttcgctgcc cagctggcgc tcgaagcgct
    15721 gggcacccac tggctgaaat tagaaatcca cccggacgcc cgttggctgc tgccggatcc
    15781 aatcgaaacg ctgaaagccg ccgaggcgct ggtgaagcaa ggttttgtgg tgctgcccta
    15841 ctgcggcgcg gatccggtgt tgtgcaagcg gctggaagag gtcggctgcg cggcggtgat
    15901 gccgcttggc gcgcctatcg gttcgaatca ggggctggaa accaaagcga tgctggagat
    15961 tattatccaa caggcgaccg tgccggtggt ggttgatgcg ggcattggcg tgcccagcca
    16021 tgccgcgcag gcgctggaaa tgggcgctga tgcggtgctg gtcaacacgg cgattgccgt
    16081 ggcggacgat ccggtgatga tggcaaccgc tttccgtctg gcggtggaag ccggattact
    16141 ggcgcgtcag gcggtgccgg gtaatcgtag cacctacgcc agcgctacca gcccgctcac
    16201 cggatttctg gaggcgttag catgaaagcc ttcaccgacc gttggcggca actggagtgg
    16261 gacgatattc gcctgcgcat caacggtaaa accgccgccg atgtggagcg ggcgctgaat
    16321 gcttcacgcc tcaaccgcga ggatatgatg gcgttgctct cccccgccgc cgccgattat
    16381 ctggaaccga tggcgcagcg ggcacaaagg ctgacccgac aacgctttgg caacaccgtc
    16441 agtttctacg tgccgctcta tctctcaaac ctctgtgcca acgactgcac ctactgcggc
    16501 ttctctatga gcaaccgcat caagcgtaag acgctggatg aggtggatat tcaaagggag
    16561 tgcgatgcta tccgtaaact gggttttgag catctgctgt tagtcaccgg cgagcatcag
    16621 gccaaagtcg gcatggacta ttttcgccgt catttaccca ccatccgccg tcaattttcc
    16681 tctttacaga tggaagtcca gcccttgtcg caagaaaact acgcggagct caaaacgctg
    16741 gggatcgatg gcgtgatggt ttatcaggaa acttaccatg aggcaatcta tgcacagcat
    16801 cacctgaagg gaaagaaaca ggactttttc tggcggctgg aaacgccgga tcggttaggc
    16861 cgggcaggta tcgacaaaat cggtcttggc gcgctaattg gtctgtcgga caactggcgg
    16921 gtggattgct atatggtggc ggagcatctg ttgtggatgc agaaacacta ttggcagagt
    16981 cgctattctg tttccttccc gcgtctgcgt ccgtgtaccg gcggtgtgga acccgcatct
    17041 gtgatggatg aaaagcaact ggtgcaaacg atttgcgcgt ttcgtttact ggcgccagaa
    17101 attgaattat cactctccac ccgcgaatcg ccgtggtttc gagaccatgt gattcctctg
    17161 gcaatcaaca acgtcagcgc cttctcgaaa acccagcccg gtggctacgc tgacgatcat
    17221 ccggaactgg agcagttttc tccccacgat gaccgtcggc cagaagtcgt tgcaagcgcg
    17281 ttaagcgcgc aagggttaca gcccgtatgg aaagactggg acagttggct ggggcgcgct
    17341 tcgcaaatgc ggtgaacccg tatgtaaacg cattaatatt tcacgagcga gtacgtaatg
    17401 tgaaaaacgg gagattgtta tcggcctccc gttttttatt ttgtcatcgt cagcaacgga
    17461 agctgaccag ggcaaattat cccttcctca tttttgccca gccttctccc cttcatcagt
    17521 aactgacgac cgggggctgg ccactggatt atcgaaatag cggtgaactt gaagttttcg
    17581 ggcagcgttc ctgactgtaa tttcgctggc ggcccctctt ccaaccgtgt ctgctgatcg
    17641 tttttgtcca taaaatgatg ccccagaaca acgggaatca ggggcgaacc catcagggaa
    17701 aaatgtgttg cggccggacg ccgatggtaa cgttacttga tggaaaacgc atctgggctg
    17761 agaaaaattt aagccagatg taatctgaca gatatctgta taaataaccg gtaactgtca
    17821 gatcaggtct gagataatac atatcatttt acctatacgc actacatcct cggacatctg
    17881 ggattggtgc attatccgat tataaagtcg tctgtgtgtt ttttcggcct aaagacctta
    17941 atggaattga atcctt
//
LOCUS       DAJVBX010000081        17952 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.081, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000081 DAJVBX010000000
VERSION     DAJVBX010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 17952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17952
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.081"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            163..2541
                     /gene="ppsA"
                     /locus_tag="OPV72_002377"
     CDS             163..2541
                     /gene="ppsA"
                     /locus_tag="OPV72_002377"
                     /EC_number="2.7.9.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate synthase"
                     /protein_id="HCR9914654.1"
                     /translation="MSNNGSSPLVLWYNQLGMNDVDRVGGKNASLGEMITNLSGMGVS
                     VPNGFATTADAFNQFLDQSGVNQRIYELLDKTDIDDVSQLAKAGAQIRQWIIDTPFQP
                     ALENAIRDAYAQLSSDDENASFAVRSSATAEDMPDASFAGQQETFLNVQGFDAVLVAV
                     KHVFASLFNDRAISYRVHQGYDHRGVALSAGVQRMVRSDLASSGVMFSIDTESGFDQV
                     VFITSAWGLGEMVVQGAVNPDEFYVHKPTLAAGRPAIVRRTMGSKKIRMVYAATQEHG
                     KQVKIEDVPQEQRDIFSLTNEEVQELAKQAVQIEQHYGRPMDIEWAKDGHTGKLFIVQ
                     ARPETVRSRGQVMERYTLHAQGKIIAEGRAIGHRIGAGTVKVIHDIGEMNRIEPGDVL
                     VTDMTDPDWEPIMKKAAAIVTNRGGRTCHAAIIARELGIPAVVGCGDATERMKDGEKV
                     TVSCAEGDTGYVYADMLDFSVKSSSVDTMPELPLKVMMNVGNPDRAFDFACLPNEGVG
                     LARLEFIINRMIGVHPRALLEFDDQDAALQNDIREMMKGFDSPREFYVGRLTEGIATL
                     GAAFYPKRIIVRLSDFKSNEYANLVGGERYEPHEENPMLGFRGAGRYVAESFRDCFAL
                     ECEAVKRVRNDMGLTNVEIMIPFVRTVDQAKAVIEELARQGLKRGENGLKIIMMCEIP
                     SNALLAEQFLEYFDGFSIGSNDMTQLALGLDRDSGVVSELFDERNDAVKALLSMAIRA
                     AKKQGKYVGICGQGPSDHEDFAAWLMEEGIDSLSLNPDTVVQTWLSLAELKK"
     gene            complement(2641..3399)
                     /gene="aroD"
                     /locus_tag="OPV72_002378"
     CDS             complement(2641..3399)
                     /gene="aroD"
                     /locus_tag="OPV72_002378"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HCR9914655.1"
                     /translation="MKTVTVKNLIIGEGMPKIIVSLMGRDINSVKAEALAYREATFDI
                     LEWRVDHFMDIASTQSVLTAARVIRDAMPDIPLLFTFRSAKEGGEQTITTQHYLTLNR
                     AAIDSGLVDMIDLELFTGDADVKATVDYAHAHNVYVVMSNHDFHQTPSAEEMVLRLRK
                     MQALGADIPKIAVMPQSKHDVLTLLTATLEMQQHYADRPVITMSMAKEGVISRLAGEV
                     FGSAATFGAVKQASAPGQIAVNDLRSVLMILHNA"
     gene            complement(3463..3570)
                     /gene="rprA"
                     /locus_tag="OPV72_002379"
     ncRNA           complement(3463..3570)
                     /ncRNA_class="antisense_RNA"
                     /gene="rprA"
                     /locus_tag="OPV72_002379"
                     /product="antisense sRNA RprA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00034"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00034"
     gene            complement(3753..4871)
                     /gene="ydiK"
                     /locus_tag="OPV72_002380"
     CDS             complement(3753..4871)
                     /gene="ydiK"
                     /locus_tag="OPV72_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter YdiK"
                     /protein_id="HCR9914656.1"
                     /translation="MVNVRQPRDIAQVLLSVLFLAIMIVACLWIVQPFILGFAWAGTI
                     VIATWPVLLKLQKILWGRRSLAVLVMTLLLVLLFVIPVALLVNSIVDGSGPLIHAVTG
                     GDMTLPDLAWLNNIPLVGAKLYAGWHSLLDMGGSAIMAKVRPYIGTTTIWFVGQAAHI
                     GRFMMHCALMLLFSALLYWRGEQVAMGIRHFACRLAAKRGDAAVLLAAQAIRAVALGV
                     VVTALVQAVLGGVGLAISGVPYATLLTVVMILSCLVQLGPLPVLIPAIIWLYWTGDTT
                     WGTVLLVWSAVVGTLDNVIRPVLIRMGADLPLLLILSGVIGGLIAFGMIGLFIGPVLL
                     AVTWRLFSAWVHEVPAPTNEPEEILEELDDIEEANKQS"
     gene            5136..8192
                     /locus_tag="OPV72_002381"
     CDS             5136..8192
                     /locus_tag="OPV72_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HCR9914657.1"
                     /translation="MIPQISQAPGVVQLVLNFLQALEQQGFTGDTATSYADRLTMSTD
                     NSIYQLLPDAVVFPRSTADVALLARLAAEPRFTSLIFTPRGGGTGTNGQALNQGIIVD
                     MSRYMNRIIEINPEEGCVRVEAGVIKDQLNQALKPYGYFFAPELSTSNRATLGGMINT
                     DASGQGSLVYGKTSDHVLGIRAVLLGGDILDTQSMPVDLARTLGENTTTPGRIYQTVY
                     QSCLENRQLILDSFPKLNRFLTGYDLRHVFNDDMTRFDLTRILTGSEGTLAFITEARL
                     DITPIPKVRRLVNVKYDSFDSALRNAPFMVDARALSVETVDSKVLNLAREDIVWHSVS
                     ELITDVPDKEMLGLNIVEFAGDDEALIDGQVEALCHRLDGLMARAEAGVIGWQLCTDL
                     TGIERIYAMRKKAVGLLGNAKGAAKPIPFAEDTCVPPEHLADYIAEFRALLDGHGLSY
                     GMFGHVDAGVLHVRPALDMCDPQQELLMKQISDEVVALTARYGGLLWGEHGKGFRAEY
                     SPAFFGEVLYGELRKIKAAFDPHNRLNPGKICPPQGIEAPMMKVDAVKRGTWDRQIPL
                     AVRQTWRGAMECNGNGLCFNFDAKSPMCPSMKISLNRIHSPKGRATLVREWLRLLADR
                     GVDPLKLEKELPEKRASLRTLIARTRNSWHKRKGEYDFSHEVKEAMSGCLACKACTTQ
                     CPIKIDVPEFRSRFLQLYHTRYLRPVRDHLVATVETYAPLMARAPKTFNFFINQPVVR
                     NLAKKHIGMVDLPLLSAPSLQQQLVGHPSANMTLEQLERMSAEQKAKTVLVVQDPFTS
                     YYDARVVADFIRLAEKLGRRPVLLPFSPNGKAQHIKGFLNRFAKTAKKTSEFLNRIAA
                     LGMPIVGVDPALVLCYRDEYKLALGEQRGDFHVLLVNEWLAQEINARLSVEVSGEPWY
                     FFGHCTEVTALPGAPAQWAAIFAHFGAKLENVSVGCCGMAGTYGHELTNHKNSLGIYE
                     LSWHQAMQRLPRNRCLATGYSCRSQVKRIEGTGVRHPLQALLEIIG"
     gene            8189..8599
                     /gene="menI"
                     /locus_tag="OPV72_002382"
     CDS             8189..8599
                     /gene="menI"
                     /locus_tag="OPV72_002382"
                     /EC_number="3.1.2.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoyl-CoA hydrolase"
                     /protein_id="HCR9914658.1"
                     /translation="MIWKREVTLDALNAMGEGNMVGLLDIRFERIGDDTLEATMPVDH
                     RTKQPFGLLHGGASVVLAESIGSVAGYLCTQGEQKVVGLEVNANHVRSARQGRVRGVC
                     KALHTGARHQVWQIEIFDEQGRLCCSSRLTTAIV"
     gene            8698..8886
                     /locus_tag="OPV72_002383"
     CDS             8698..8886
                     /locus_tag="OPV72_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416200.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdiH family protein"
                     /protein_id="HCR9914659.1"
                     /translation="MSIDLDPTQLAIEFLRRDKTELSPAQYLKRLKQLELEFADLLTL
                     SATELKEEIYFAWRLGVH"
     gene            complement(9174..10520)
                     /locus_tag="OPV72_002384"
     CDS             complement(9174..10520)
                     /locus_tag="OPV72_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HCR9914660.1"
                     /translation="MVVTLAYIALFLVFSWAILRINQKSDSLSKSVFIAIFLGAVIGL
                     SLHFISANHTKTIIEWYSIVGNGYVHLLKLVAIPLIFISILSAINKLENSAGIGKMSL
                     TIVGCMLCLVMVAGFIGLLTAHILGLDASAFVHMPSMLTTEEVNKTAAVSIPQLVTSL
                     IPTNIFLDLTGARSVSVIGIVIFTLIAGIALLKVKKEAPEEGQKLSAGINAIQIWVMK
                     MVRIVIALTPYGVMALMTTVFSSYRLEQFASLLGFIGACYIAIFMMFIVHAILLILSG
                     NNPAHYFRMVWPVLTFAFVSRSSAASIPLAISAQEKFGVQSTIANISASFGSSMGQNG
                     CAGIYPAIMVAMIAPTIGIDPLSLHFLAAMLPAIALGSIGVAGVGGGGTFAALIVLST
                     LNFPVALVGIFIAIEPIVDMARTALNVNGSMMSGVLANRILNNNRADDMPAVIDRP"
     gene            10947..11315
                     /gene="sufA"
                     /locus_tag="OPV72_002385"
     CDS             10947..11315
                     /gene="sufA"
                     /locus_tag="OPV72_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold SufA"
                     /protein_id="HCR9914661.1"
                     /translation="MELHSGTFNPEDFPWQGLTLTPAAAAHIRELAAKQPGMLGVRLS
                     VKQTGCAGFGYVLDTVREPDKDDLVFEAEGAKLFAPLQAMPFIDGTEVDYVQEGLNQL
                     FKFHNPKAQNECGCGESFGV"
     gene            11324..12811
                     /gene="sufB"
                     /locus_tag="OPV72_002386"
     CDS             11324..12811
                     /gene="sufB"
                     /locus_tag="OPV72_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HCR9914662.1"
                     /translation="MSRNTEATEEVGIWTGGRLNYKEGFFTQLPTDELAKGISEEVVR
                     AISAKRNEPDWMLEFRLNAYRAWLDMDEPHWLKAHYDKLNYQDYSYYSAPSCGNCDDS
                     CVSQPGAVQQTGANTFLSKEVEDAFEQLGVPVREGKEVAVDAIFDSVSVATTYREKLA
                     EQGIIFCSFGEAIHDHPDLVRKYLGTVVPGNDNFFAALNAAVASDGTFIYVPKGVRCP
                     MELSTYFRINAEKTGQFERTILVADEGSYVSYIEGCSAPVRDSYQLHAAVVEVIIHKD
                     AEVKYSTVQNWFPGDNNTGGILNFVTKRALCEGENSKMSWTQSETGSAITWKYPSCIL
                     RGDNSIGEFYSVALTSGHQQADTGTKMIHIGKNTRSTIISKGISAGHSQNSYRGLVKI
                     MPTATNARNFTQCDSMLIGADCGAHTFPYVECRNNSAQLELEATTSRIGEDQLFYCLQ
                     RGISEEDAISMIVNGFCKDVFSELPLEFAVEAQKLLAISLEHSVG"
     gene            12828..13574
                     /gene="sufC"
                     /locus_tag="OPV72_002387"
     CDS             12828..13574
                     /gene="sufC"
                     /locus_tag="OPV72_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008500629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HCR9914663.1"
                     /translation="MLSIKDLQVSVEEKAILRGLNLDIRPGEVHAIMGPNGSGKSTLS
                     ATLAGREDYEVTGGSVTFKGKDLLELSPEERAGEGIFMAFQYPVEIPGVSNQFFLQTA
                     LNAVRAYRGQASLDRFDFQDLMEEKIALLKMPEDLLTRSVNVGFSGGEKKRNDILQMA
                     VLEPELCILDESDSGLDIDALKIVAEGVNALRDDKRAFIIVTHYQRILDYIKPDYVHV
                     LYQGRIVRSGDFTLVKQLEEQGYGWLTEQQ"
     gene            13549..14820
                     /gene="sufD"
                     /locus_tag="OPV72_002388"
     CDS             13549..14820
                     /gene="sufD"
                     /locus_tag="OPV72_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HCR9914664.1"
                     /translation="MAGLPNSSKALQQWQHLFEEKGEIRTEQARQHFQQMLRLGLPTR
                     KHEDWKYTPLEGLTHSQFIQQCATISAAQRDALALQIDAVRLVFVDGRFMPELSDSTQ
                     NSGFDVSVRDERQTLAAPVHPEVFLHLTESLAQCVTYIQVRRNQRPTRPLLLMHITQG
                     VDSDELNTAHYRHHLTLAEGAEATVIEHYVSLTAAKHFTGARLTMNVADNAQLRHIKL
                     AFENASSYHFAHNDLLLATDASAFSHSFLLGAAVLRHHSSSQLNGENATLRLNSLAMP
                     VKNEVCDTRTWLEHNKGYCNSRQLHKTIVSDKGRAVFNGLINVAQHSIKTDGQMTNNN
                     LLLGKLAEVDTKPQLEIYADDVKCSHGATIGRIDDEQMFYLQSRGIRQQEARHMILYA
                     FAAELTEAIHDSALKQQVLARIGQRLPGGLV"
     gene            14817..16037
                     /gene="sufS"
                     /locus_tag="OPV72_002389"
     CDS             14817..16037
                     /gene="sufS"
                     /locus_tag="OPV72_002389"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase SufS"
                     /protein_id="HCR9914665.1"
                     /translation="MTFPVEKVRADFPILQREVNGLPLAYLDSAASAQKPNQVIDAES
                     AFYRHGYAAVHRGIHTLSAQATESMENVRKQASRFINARSAEELVFVRGTTEGINLVA
                     NSWGTENIRAGDNIIISEMEHHANIVPWQMLCERKGAELRVIPLHPDGTLRLETLAAL
                     FDDRTRLLAITHVSNVLGTENPLPDMIALARQHGAKVLVDGAQAVMHHAVDVQALDCD
                     FYVFSGHKLYGPTGIGILYVKEALLQEMPPWEGGGSMISTVSLTQGTTWAKAPWRFEA
                     GTPNTGGIIGLGAAIDYVTSLGLDKIGDYEQMLMRYALEQLAQVPDITLYGPAQRLGV
                     IAFNLGKHHAYDVGSFLDNYGIAVRTGHHCAMPLMAWYGVPAMCRASLAMYNTHEEVD
                     RLVAGLTRIHRLLG"
     gene            16050..16466
                     /gene="sufE"
                     /locus_tag="OPV72_002390"
     CDS             16050..16466
                     /gene="sufE"
                     /locus_tag="OPV72_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfuration protein SufE"
                     /protein_id="HCR9914666.1"
                     /translation="MAALPDKEKLLRNFTRCANWEEKYLYIIELGQRLAELNPQDRNP
                     QNTIHGCQSQVWIVMRRNANGIIELQGDSDAAIVKGLMAVVFILYHQMTAQDIVHFDV
                     RPWFEKMALTQHLTPSRSQGLEAMIRAIRAKAATLS"
     gene            16621..17621
                     /locus_tag="OPV72_002391"
                     /pseudo
     CDS             16621..17621
                     /locus_tag="OPV72_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460340.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
     gene            complement(17688..17927)
                     /locus_tag="OPV72_002392"
     CDS             complement(17688..17927)
                     /locus_tag="OPV72_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major outer membrane lipoprotein"
                     /protein_id="HCR9914667.1"
                     /translation="MNRTNKLILGAVVLGSTLLAGCSSNAKIDQLSSDVQTLSAKVDQ
                     LSNDVNAMRSDVQAAKDDAARANQRLDNKVFRICK"
BASE COUNT         4427 a         4477 c         4986 g         4062 t
ORIGIN      
        1 tgctatgcgc gggtttgcgc aactacgtaa acaatctgaa aaaatgaaaa aataaatttg
       61 cttgaacgat tcaccgtttt tttcgcgggt ttaagtatgc caggataaat acgcaactat
      121 gtgtttctta aactcgttca tttatcacaa aaggattgtt cgatgtccaa caatggctcg
      181 tcaccgctgg tgctttggta taaccaactc ggcatgaatg atgtagacag agttgggggc
      241 aaaaatgcct ccctgggtga aatgattact aacctttccg gcatgggcgt atccgttccg
      301 aatggttttg caaccactgc cgatgcgttt aaccagtttt tggatcaaag cggcgtaaac
      361 cagcgcattt atgagctgct ggataagaca gatattgatg atgtctccca gctggcgaaa
      421 gcgggcgcgc agatccgcca gtggattatc gacactcctt tccagccggc gctggaaaac
      481 gccatccgcg atgcctatgc gcagctttcg tcggatgatg aaaatgcctc ttttgccgtg
      541 cgttcctccg ccacggcgga agacatgcca gatgcttcgt ttgcgggtca acaggaaacg
      601 tttcttaacg ttcagggctt cgatgcggta ctggtggcag tgaaacacgt atttgcttct
      661 ctgtttaacg atcgcgccat ctcttatcgc gttcaccagg gatatgatca tcgcggcgta
      721 gcgctttccg ctggcgtgca gcggatggtt cgctccgatc tcgcctcgtc aggggtgatg
      781 ttctctatcg ataccgaatc cggctttgac caggtggtct ttatcacctc ggcatgggga
      841 ctgggtgaaa tggtggtgca gggcgcggtt aacccggatg aattttatgt ccataagcca
      901 accctggcgg caggccgtcc ggccatcgta cgccgcacca tggggtcgaa aaaaatccgc
      961 atggtttacg ccgccaccca ggagcacggt aagcaagtga agattgagga tgtgccgcag
     1021 gaacagcgcg acattttctc gctcaccaac gaagaagtgc aggaactggc gaaacaagcg
     1081 gtgcagattg agcagcacta tggtcgtccg atggatatcg aatgggcgaa agacggtcat
     1141 accggtaagc tctttattgt gcaggcacgt ccggaaaccg tgcgctctcg tggccaggtg
     1201 atggagcgtt atacgttaca tgcgcagggg aaaatcattg ccgaaggtcg tgccattggg
     1261 catcgtatcg gcgcaggtac ggtaaaagtt attcacgata tcggcgaaat gaaccgtatt
     1321 gagcctggcg atgtgcttgt caccgatatg accgacccgg actgggaacc gatcatgaaa
     1381 aaagcggcgg cgattgtcac taaccgtggc gggcgcacct gtcacgcggc gattatcgcc
     1441 cgcgaattgg gcattccggc ggtagtcggc tgcggcgacg ccaccgaacg catgaaagat
     1501 ggcgaaaaag taaccgtctc ctgtgcggaa ggtgataccg gttatgtgta tgccgacatg
     1561 ctggatttca gcgtaaaaag ctccagcgta gataccatgc cagagctacc gctgaaggtc
     1621 atgatgaacg tcggcaaccc ggacagggca tttgactttg cctgcctgcc gaatgaaggc
     1681 gtaggtctgg cgcgactgga attcatcatt aaccgtatga ttggcgttca cccgcgcgcg
     1741 ttgctggagt ttgacgacca ggatgccgcg ctgcaaaacg acattcgtga gatgatgaaa
     1801 gggtttgact cgccgcgtga attttacgtt ggtcgactga cggaagggat cgcgacgtta
     1861 ggcgccgcct tctacccgaa acgcattatc gttcgcctgt ctgactttaa gtccaacgaa
     1921 tacgccaacc tggtcggcgg cgaacgttat gagccgcatg aagaaaaccc gatgctgggc
     1981 ttccgcggcg cgggtcgtta cgtcgcagaa agtttccgcg attgttttgc gctggaatgc
     2041 gaagcggtga aacgcgtgcg caacgatatg ggccttacca acgtcgaaat catgatcccg
     2101 ttcgtgcgga cggtcgacca ggcgaaagcg gtcatcgaag agctggcgcg ccagggactt
     2161 aaacgcggcg agaacgggct gaagatcatc atgatgtgcg agattccgtc caatgccttg
     2221 ctggctgaac agttcctcga gtattttgat ggcttctcga ttggttctaa cgacatgacg
     2281 cagctggcgc tggggctgga tcgcgattcc ggcgtggtgt ctgaactgtt tgacgagcgt
     2341 aacgacgcgg tgaaagcgct gctatcgatg gcgatccgcg cggcgaaaaa acagggcaaa
     2401 tatgttggaa tttgcggcca gggcccgtcc gaccatgaag actttgccgc ctggctgatg
     2461 gaagagggga tcgacagcct gtcgctgaac ccggacaccg tggtgcagac ctggctgagt
     2521 ctggcggaac tgaagaagta aaccgcgacc agataacgct atgcttatcc ggcctgcaca
     2581 agaaacatgt tgtgtcggcc ggatagggcg taagttgccc gacgcctgca taatgccgga
     2641 tcaggcgttg tgcagaatca ttaatacact gcgtagatca tttacggcga tttgccccgg
     2701 cgctgaagcc tgcttcaccg cgccaaacgt ggcggcagag ccaaacactt cccctgccag
     2761 acgtgaaatg acaccctctt tcgccattga catagtaatt accggacggt cggcgtaatg
     2821 ttgctgcatc tccagcgtgg cagtgagtaa cgttaataca tcatgcttgc tttgcggcat
     2881 aacggcaatc ttgggaatat ccgcgccgag tgcttgcatt ttacgtagcc gcagaaccat
     2941 ttcctctgcg gacggcgtct ggtgaaaatc gtggttagac atcacgacat aaacattatg
     3001 cgcatgggca taatcgacag tggctttaac gtcagcatca ccggtaaata gctcaagatc
     3061 gatcatatcg accaggccgc tgtcgattgc ggcacgatta agcgtgagat aatgctgagt
     3121 ggttattgtc tgctcgccgc cttctttggc gctgcggaaa gtaaacagta acggaatgtc
     3181 aggcatcgca tcgcggataa cacgcgcagc ggtaagaacg gattgagtcg atgcgatatc
     3241 cataaagtga tccacgcgcc actccagaat atcgaatgta gcttcgcggt aggccagcgc
     3301 ctccgctttc acgctattga tgtctcttcc catcaacgac acgataattt tgggcatccc
     3361 ttcgccaatg ataagatttt ttacggtgac ggttttcatg cgtgtcctgt cagttttttt
     3421 tcttctcgcc attatgaacg gtgaggctgg ccgcttgaag taaaaaaaaa aagcccatcg
     3481 taggagacgg gcaaagacta cacacagcaa ttcgttgttt cactcagggg atttccatgc
     3541 ttataaatca atgtgttgat ttataaccgt gtgctaatag taggcatgag cactttttgc
     3601 gtcgatcaga ttcgtctcaa tagtttaaaa actgtaacgg atttgcgaca gaaatgagat
     3661 gcggcgggga acagacgggc gaatcaaaat ggggtgtgcg ttgaattgat aaacgtcgct
     3721 aaagcatcgg gcggcaatgc cgcccgacgg gattatgact gcttgttggc ttcctcgatg
     3781 tcatccagct cttcaaggat ctcctctggt tcattcgtcg gcgccggaac ttcatgtacc
     3841 catgcggaga acaaacgcca ggtcacggcc agaagcaccg gtccaataaa cagaccaatc
     3901 ataccgaatg caatcaggcc gccgattacc ccggaaagga tcagaagcag cggtaaatcg
     3961 gcgcccatgc ggatgagtac cgggcgaatc acgttatcca gagtgccgac gacggcgctc
     4021 caaaccagca gcacggtgcc ccaggtggtg tcgcctgtcc agtaaagcca gataatggct
     4081 ggaatcaata ccggcaacgg ccccaactga accaggcacg aaaggatcat cactaccgtc
     4141 aacagggtag cgtaaggcac gccggaaatc gccagcccga cgccgccaag taccgcctgt
     4201 accagcgcgg tgaccaccac gccaagcgcc acggcgcgga tcgcctgggc agccagcaga
     4261 accgccgcat cgccgcgttt agccgcgaga cgacaggcaa aatggcgtat acccatcgcc
     4321 acttgttcgc cgcgccagta aagcagggcg ctaaacaaca gcatcagggc gcagtgcatc
     4381 ataaagcgtc cgatatgcgc cgcctgaccg acaaaccaga tcgtggttgt gccgatataa
     4441 ggccgcactt tcgccataat agcgctaccg cccatatcca gcaggctatg ccatccggca
     4501 tacagtttgg cgccaactaa cggaatatta tttaaccatg ccagatcggg tagcgtcata
     4561 tcgccgccgg tcactgcatg gatgagcggg ccgctaccat cgacaatgct gttcaccagc
     4621 aaggcgacgg gaataacgaa gagcagcact aacagcagcg tcatgaccag tacggcaagc
     4681 gagcggcggc cccacaatat tttttgtaat ttcagcaaaa cgggccaggt cgcgataaca
     4741 atcgtacctg cccatgcaaa ccccaaaata aaaggctgta ctatccacaa acaggccaca
     4801 atcatgatgg ctaaaaacag caccgatagc agcacttgcg caatatccct gggctgacga
     4861 acatttacca taaatacttt tcacctttgt ctttgcgcca gaacgttggc gcgacgtgaa
     4921 catgcaaacc acaccctata atgatgagca atttcagcgg tttttaacag gccgattctg
     4981 catgtaattc tgttgggcgc acaggaaaaa aatgtgatac aacaaataac gcaacacgca
     5041 aacgattaag catcccttcc tgtgcgtaga ccgctcgcgc tcgccgggtt gggcgccacc
     5101 gttcacaaca tagaccgcag gaaaaggtca atataatgat tccacaaatt tctcaggcac
     5161 ccggcgtcgt tcagctggtg ctcaattttt tgcaggcgct ggagcagcaa gggtttacgg
     5221 gcgatacggc aaccagctat gccgaccgtc tgacaatgtc gaccgataac agtatctacc
     5281 agcttcttcc cgatgctgtt gtgtttcccc gttctacggc ggatgtcgcg cttcttgccc
     5341 gtctggcggc ggagccgcgc tttacgtcgc tgatatttac cccgcgaggc ggcggtactg
     5401 gcacgaatgg ccaggcgcta aaccagggca ttattgttga tatgtcccgc tatatgaacc
     5461 gcattattga aattaatcct gaagagggat gtgtgcgggt agaggcggga gtgataaaag
     5521 atcagcttaa tcaagcgtta aagccgtatg gctatttttt tgcgccggaa ctttccacca
     5581 gtaatcgcgc cacgcttggc ggtatgatta ataccgatgc ctctggtcag ggttcgctgg
     5641 tctatggaaa aacgtcagat cacgtcttag gcatacgggc cgtattgttg gggggcgata
     5701 tccttgacac gcaatcgatg cccgtagatc ttgcccggac gctgggtgaa aacacgacga
     5761 cgccaggccg catctatcag accgtctatc agtcctgcct ggaaaaccgt caacttatcc
     5821 tcgatagctt tccaaagctc aatcgcttcc tgacaggcta cgatttacgc cacgtcttta
     5881 acgatgacat gacccgcttc gatctcaccc gcatcttaac ggggtcggaa gggacgctgg
     5941 cgtttattac tgaagcccgg ctggatatta ccccgatacc caaagtccgc cgtctggtga
     6001 atgtaaaata cgactccttt gattccgcgc tgcgtaacgc cccttttatg gttgacgcgc
     6061 gcgccttatc cgtcgagacg gtcgattcca aagtccttaa ccttgcgcgg gaagatattg
     6121 tctggcactc cgttagcgaa ttgattaccg atgtgccgga taaagagatg cttggcctga
     6181 atatcgtgga attcgcgggt gatgatgaag cgcttattga cggacaggtc gaggcgctgt
     6241 gccaccgact ggatggcctg atggcgcgtg cggaagcggg cgtgatcggc tggcaacttt
     6301 gtaccgattt gacgggtatt gagcgtattt acgcgatgcg taaaaaagcg gtagggctgc
     6361 tgggtaatgc gaaaggcgct gccaaaccga ttccttttgc ggaagatacc tgtgtgccgc
     6421 ctgaacatct ggccgattac atcgccgaat ttcgcgctct gctggatggt catggcttaa
     6481 gttacggcat gttcggccac gtggatgccg gggtgctgca tgtgcgcccg gcgctggata
     6541 tgtgcgatcc gcagcaggaa ctgttgatga aacagatctc cgatgaggtc gtcgcgctga
     6601 ccgccagata cggcgggttg ttgtggggcg aacatggaaa aggtttccgt gcggaataca
     6661 gcccggcctt tttcggcgaa gtcctgtatg gcgagctgcg caaaataaaa gcggcttttg
     6721 atccgcataa tcgacttaac ccgggtaaaa tctgtccgcc gcaggggata gaggcgccga
     6781 tgatgaaggt ggatgcggta aaacgcggca cctgggatcg gcaaatcccg ctggcggtgc
     6841 ggcagacctg gcgcggcgct atggagtgta atggtaacgg cctgtgcttt aatttcgatg
     6901 cgaaaagccc gatgtgcccg tcgatgaaaa ttagccttaa ccggatccac tcgccgaaag
     6961 ggcgggcgac gctggtgcgg gaatggctcc gtctattggc cgatcgcggc gtcgatccgt
     7021 tgaagctgga aaaggagctg ccggaaaaac gcgccagctt gcgcacgctg attgcccgca
     7081 cccggaatag ttggcacaaa cgcaaaggcg agtatgactt ttcccatgaa gttaaagagg
     7141 ccatgtccgg ctgtctggca tgtaaagcct gtacgaccca gtgtccgatt aaaatcgatg
     7201 ttccggagtt tcgttcacgt ttcttacagc tttaccatac gcgttatctg cgcccggtac
     7261 gcgatcatct ggtggcgacg gtcgagacct acgcgccgct gatggcgcgt gcgccaaaga
     7321 cctttaactt ttttattaac caaccggtgg ttcgtaatct ggcgaaaaaa catatcggta
     7381 tggtggattt acctctgctt tctgcccctt cattgcaaca gcaactggtg ggccatccgt
     7441 ctgccaatat gacgcttgag caactggagc gcatgagcgc cgagcaaaaa gcgaaaacgg
     7501 tactggtagt tcaggatccg tttaccagct actacgacgc tcgggtcgta gcggacttta
     7561 tccgcctggc ggaaaaactg ggcaggaggc cggtattgtt accgttctcg ccgaatggta
     7621 aggcgcagca tattaaaggt tttcttaatc gctttgcgaa aacggcgaaa aaaacctctg
     7681 agttccttaa tcggatcgcc gcgttgggga tgccaatagt gggcgtcgat ccggcgctgg
     7741 tcctgtgtta tcgcgacgaa tataaactgg cgctgggcga acagcgcggc gattttcatg
     7801 tgttgctggt gaatgaatgg ctggcgcagg aaataaatgc aagactgtcc gtcgaggtaa
     7861 gcggtgaacc gtggtacttt tttggtcatt gtacggaagt cacggcttta cccggcgcgc
     7921 ctgcgcagtg ggccgccatc tttgcccatt ttggcgcgaa gctggaaaat gtcagcgtag
     7981 gctgctgcgg tatggcgggc acttatggac atgaactcac caatcataaa aattcgctgg
     8041 gaatttatga gctatcctgg catcaggcga tgcaacgtct accgcgaaac cgctgcctgg
     8101 caaccggcta ttcctgccga agccaggtta aacgcattga aggtacgggc gtgcgtcacc
     8161 cgttgcaggc attactggag attataggtt gatctggaaa cgtgaagtga ccctcgatgc
     8221 gcttaatgcg atgggggaag ggaatatggt tggcctgctt gatatccgct ttgagcgtat
     8281 tggggacgat acgctggaag cgacaatgcc cgtcgatcat cgcaccaaac agccgttcgg
     8341 cttgctgcat ggcggagcgt ctgtggtgct ggcggaaagt atcggctcgg tcgcaggcta
     8401 tctgtgtacg cagggggagc aaaaggtggt ggggctggag gtgaatgcca accatgtacg
     8461 gtcggcgcgt caggggcgcg tacgaggcgt ctgtaaagcg ttgcataccg gggctcgcca
     8521 tcaggtctgg cagatagaga tctttgatga acagggacgt ctgtgctgtt cttcgcgcct
     8581 tactacggcg attgtgtgac gttgtcacca taaaagtgtg atgcatattg cttttggtca
     8641 aaatgtgcgc agaaaaaggt gatatactgt gcacgtttac acataagcga ggatgatatg
     8701 tctattgatt tagacccaac ccaactggcg attgaatttt tacgccgtga taaaaccgaa
     8761 ctttctcccg cgcagtattt gaagcgttta aaacagctgg agttagagtt tgccgatctc
     8821 ctcaccctct ctgcaaccga actgaaagaa gagatctatt tcgcctggcg gttgggcgtg
     8881 cattaataga gtctgtgtag gccggataag gcgttagccg ccatccggct atgttaccag
     8941 gcaatctcac cagacactgt cccccggtaa tagataaccc ccttgatttt gtgtaaaaaa
     9001 aatacagatc gccatttgtg ctaaaaaggt gcgctctctt tatgagatta ttcttatgcc
     9061 ccttcaagag ctaagccatt aagagtgccg gagataagcg ccggatgggg ccggaaccct
     9121 taagcctgta ttgaacagac ttaagggttt ttcttttccg ggcgcgtaaa aaactaaggt
     9181 ctgtcaataa ccgctggcat gtcgtcagcc ctattattat tcaaaatacg gttagccagc
     9241 acacctgaca tcatcgatcc gttaacgttc agagccgtgc gggccatatc aacgataggt
     9301 tcgatggcaa taaaaatacc gaccagcgca acgggaaaat tcaacgtcga caggacaatc
     9361 agcgccgcga acgtaccacc gccgccgacg ccggctacgc caatagaccc tagcgcaatg
     9421 gcaggcaaca tcgcggccag aaaatgcagc gagagcggat cgatgccgat ggtgggcgca
     9481 atcatcgcta ccataatagc cggataaatc ccggcgcagc cattttgccc catactggag
     9541 ccaaacgagg cggaaatatt ggcaatggtg ctttgtacgc caaatttttc ctgggcggaa
     9601 atggccagcg gaatagaggc tgcgctgctg cgggagacaa acgcaaaggt taagacgggc
     9661 cagaccattc tgaaataatg cgctggatta ttaccgctga ggatcagcaa gatggcgtgc
     9721 acgataaaca tcatgaaaat cgcgatataa caggcgccga taaaaccaag taagctggcg
     9781 aattgttcaa ggcggtatga tgaaaatacg gtggtcatta atgccatgac gccatagggc
     9841 gttaatgcaa taacgatacg taccatcttc atgacccaga tctggatagc gttaatgcct
     9901 gcgcttaatt tctgaccttc ttccggcgcc tcttttttga cctttaacag ggcgatcccc
     9961 gctattagcg tgaagataac gatgccgata acggaaacac ttctggctcc cgtaagatca
    10021 agaaaaatat ttgtcgggat cagcgatgtc actaactggg gaatcgacac cgcggcagtc
    10081 ttattgactt cttctgtagt taacattgac ggcatgtgca caaaagcgct ggcgtcaagc
    10141 cccagtatat gagcggtcag taatccgata aaaccggcaa ccatcaccag gcataacatg
    10201 catccgacga tcgtcagcga catttttccg atgccggcgc tattttccag tttattgatg
    10261 gcggaaagaa tagaaataaa aattagcggt atagcgacca gttttaacag atggacgtag
    10321 ccattgccga cgatgctgta ccattcgata atggttttag tgtgatttgc tgaaataaaa
    10381 tgcagggata aaccaataac agcccctaaa aagatagcga taaaaacgct tttcgacagg
    10441 gaatcgcttt tttgattaat tctcaagatg gcccacgaga aaaccaaaaa aagtgcgata
    10501 tacgcgagcg taacaaccat attttaagcc tcttgcctca ttcagcacct gaaatgccgg
    10561 aaagagttta cataaaccta tagctcaaac tgagttatag aaccgcagcg gattataaag
    10621 agcgcaacgc caggtatcca tacaaaaaat ggggttctga cctcgccgcc cggcaatgtc
    10681 gacagcctat taattaaata gtcattttct atacatcttt tcgtttttga cctgccagaa
    10741 cggttaatgt cttataaatc attacttatc aaaaagttaa gtggtttttt gtctgtcgta
    10801 tgacctggcg gacagggtct atgcttaata aaaggcgctc aatatgacca tttgttggaa
    10861 agcccctgcg gttaaggggt tgaagtgata atcattatca ctaacatgct gttatatcct
    10921 ggtgatttag aacgcgaggt aactctatgg aattgcattc aggcacgttt aacccggagg
    10981 acttcccctg gcaagggctg acgctaacgc cagcggcggc agcgcacata cgtgaactgg
    11041 cagcaaagca gccgggcatg ttgggcgtgc ggttaagcgt aaaacagacg ggatgtgccg
    11101 gatttggcta tgttctggat accgttcggg agccggataa agacgatctg gtttttgaag
    11161 ccgaaggcgc aaagcttttc gcaccgttac aggcgatgcc ttttattgac ggaacagaag
    11221 tggattacgt acaggaaggg ctgaaccagt tatttaaatt tcataacccc aaagcccaga
    11281 atgaatgtgg ctgcggcgaa agttttgggg tataggcggt actatgtctc gtaatactga
    11341 agcaacggaa gaggtcggca tctggacagg cggacgcctt aattacaaag aaggattttt
    11401 cacgcaatta cccactgatg aactggcaaa aggcatcagc gaagaggtgg tgcgtgcgat
    11461 ttccgcaaag cgtaacgaac ctgattggat gctggaattt cgcctcaatg cctatagagc
    11521 ctggctggac atggatgaac cgcactggct gaaagcgcat tacgataaac tgaactatca
    11581 ggactacagc tattactctg cgccatcatg cggaaactgc gacgatagct gcgtttccca
    11641 gccgggagcc gtacagcaaa cgggcgcgaa tacctttttg agtaaagagg ttgaagacgc
    11701 tttcgagcaa cttggcgttc cggttcgcga agggaaagag gtcgccgttg atgcgatttt
    11761 tgactcggtc tccgtagcga ccacataccg tgaaaaactg gcggaacagg gcattatttt
    11821 ctgttctttt ggcgaagcga tacacgatca ccctgacctg gtcaggaaat atcttggcac
    11881 cgtcgtgccg gggaacgata acttttttgc cgcgctgaat gcggcagtcg cttccgatgg
    11941 gacatttatc tatgttccca aaggcgtgcg ttgcccaatg gagttatcca cctattttcg
    12001 cattaacgct gagaaaaccg gtcagtttga gcgcacgatt ctggtggcgg atgaaggcag
    12061 ctatgtgagt tatatcgaag gctgctccgc gcccgtacgc gacagttatc agctccacgc
    12121 cgcggtagtg gaagtcatca tccataaaga tgctgaagta aaatattcca ccgtacaaaa
    12181 ctggttcccg ggcgacaaca acacgggcgg cattctgaac tttgtgacca agcgggcgtt
    12241 gtgcgaaggg gaaaacagca agatgtcgtg gacccagtcg gaaaccggtt cggcgattac
    12301 ctggaaatac ccgagctgca ttctgcgcgg tgataattct atcggcgagt tctattccgt
    12361 tgcgctgacc agtggacatc agcaggctga caccggcacc aaaatgatcc atatcggtaa
    12421 aaacacgcgc tcaaccatta tctcaaaagg catttccgcc ggccacagcc agaacagcta
    12481 ccgtgggctg gtaaaaatta tgccgacggc aaccaacgcc cgaaatttca cccaatgcga
    12541 ctccatgttg attggcgcgg actgcggcgc gcatacgttc ccgtatgttg aatgccgcaa
    12601 taacagcgcg cagctggagc tcgaggcgac gacatcacgc atcggtgaag atcagctttt
    12661 ctattgtctg caacgcggca tcagcgaaga agacgctatt tcgatgatcg tcaacggttt
    12721 ctgcaaagac gttttctcgg aactgccgct ggagttcgcc gttgaagcgc aaaaactgct
    12781 ggcgattagc cttgagcaca gcgtcggtta atgatgaagg aaaacccatg ttaagcatta
    12841 aagatttaca ggtcagtgtg gaagaaaagg cgattttgcg tggcctgaat ctggatattc
    12901 gccccggcga agttcacgcc attatggggc cgaacggttc cgggaaaagc acgctctccg
    12961 ccaccctggc gggacgtgaa gattatgagg tcaccggcgg ctcggttacg ttcaaaggta
    13021 aagatctgct tgaactgtcg ccggaggaac gggcgggcga agggattttt atggccttcc
    13081 agtacccggt agaaatcccc ggcgtcagta accagttttt cctgcaaacc gcgctgaatg
    13141 ccgtgcgcgc ctatcgaggg caggcgtcgt tggatcgctt tgattttcag gatctgatgg
    13201 aagaaaagat cgcattgctg aaaatgccgg aagatttgct gacccgttcg gtaaacgtcg
    13261 gtttttccgg cggggagaaa aagcgcaatg atattttgca aatggcggtg ctggaaccgg
    13321 aactgtgcat tcttgatgag tcggactccg gactggatat cgatgcgttg aaaattgtgg
    13381 cggaaggcgt caacgcgtta cgcgacgata aacgcgcttt tattatcgtg acccactatc
    13441 agcgcatact ggactacatc aagcctgatt acgtccatgt cctctatcag gggcgaattg
    13501 tccgttccgg cgattttact ctggtcaaac aactggagga gcagggttat ggctggctta
    13561 ccgaacagca gtaaagcgct acagcaatgg cagcatctct ttgaagaaaa aggagaaatt
    13621 cgaactgagc aggcaagaca acatttccaa cagatgttac gtctgggatt gccgacgcgt
    13681 aaacatgaag actggaaata cacgccgctg gagggcttaa cccatagcca gtttatccag
    13741 cagtgtgcga ctatcagcgc cgcccagcgt gatgcgctgg cgctgcaaat cgatgccgtg
    13801 cggctggtgt ttgtcgacgg acggtttatg ccagagctca gtgatagcac gcaaaacagc
    13861 ggatttgacg ttagcgtcag agatgagcgc cagacgcttg ccgcgccggt acatcccgag
    13921 gtttttctgc atctgacgga aagcctggcg caatgtgtca cgtatataca ggtacggcga
    13981 aatcagcgtc cgaccaggcc gctactgtta atgcatatca cgcagggcgt ggatagcgac
    14041 gagctgaata ccgcgcatta tcgccaccat ctgacgctgg cagaaggcgc ggaagcgacg
    14101 gttattgagc attatgtcag ccttacagcg gcaaaacatt ttaccggcgc gcgtctgacg
    14161 atgaacgttg cagacaatgc gcaactgcgt catatcaaac tggcgtttga aaatgcgtcc
    14221 agctatcact ttgcgcataa cgatcttctg ctggcgacag acgcctcggc gtttagccac
    14281 agttttctgc tgggcgccgc agtactacgt caccacagca gctcacaact gaatggcgaa
    14341 aacgcgacgc ttcgactgaa tagtctggcg atgccagtga aaaatgaagt ctgcgatacg
    14401 cggacatggc tggaacataa caaaggctac tgtaacagcc gccagttgca caagaccatc
    14461 gtcagcgaca aaggacgcgc ggtctttaat ggcctgatta acgtggcgca acactccatt
    14521 aaaaccgacg gccagatgac caataataac ctattgttgg ggaaactggc tgaagtcgat
    14581 accaaaccgc aattagagat ctatgccgat gacgtgaagt gcagccacgg cgcgacgatc
    14641 gggcgtattg acgatgagca gatgttttat ctgcaatcac gcggcatcag gcagcaggag
    14701 gcgcggcaca tgattcttta cgcgtttgcc gcagagttaa cggaagctat ccatgatagc
    14761 gcccttaaac agcaggtgct ggcgcgaatc ggccagcgac tgcccggagg cctggtatga
    14821 catttcctgt agaaaaagta cgggcggatt ttcccatact gcagcgtgaa gttaacggcc
    14881 tgccgctggc ttacctggac agcgcagcca gcgctcaaaa acctaatcag gtgattgatg
    14941 ctgaatctgc cttctaccgt cacggctatg ctgcggtaca tcggggtatc catacgttaa
    15001 gcgcgcaggc gaccgaaagc atggagaatg tgcgtaagca ggcgtcgcgg tttattaacg
    15061 cccgctccgc agaagaactg gtgttcgtgc gcggtacgac ggagggcatt aaccttgtcg
    15121 ccaacagttg gggaacggaa aatattcgcg ccggggataa cattatcatc agcgagatgg
    15181 agcatcacgc caacatcgtt ccctggcaga tgctgtgcga gcgcaaaggc gctgaactgc
    15241 gcgtgatccc attgcatcct gacggtacgc tgcggctgga gaccttagct gcgctgttcg
    15301 atgaccggac ccgactgctg gccattaccc atgtatctaa tgtgctgggg acggaaaacc
    15361 cactgccgga catgattgcg ctggcgcgcc agcatggggc gaaagtgctg gtggatggcg
    15421 cccaggccgt gatgcaccat gctgttgacg tccaggcgct ggactgcgat ttttacgttt
    15481 tctccggcca taaactttac gggccgaccg gcatcggcat tctgtatgtt aaagaggcgt
    15541 tgctgcaaga aatgccgccg tgggaagggg gcgggtcgat gatctcgacc gtcagcctga
    15601 cgcagggaac gacatgggcg aaagcgccct ggcgttttga ggcgggaacg ccgaatactg
    15661 gcggcatcat cggtctcggc gcggcgattg attatgtgac gtcgctggga ctggataaga
    15721 ttggcgatta tgagcagatg ctgatgcgct atgcgctgga gcaactggcg caggtgcctg
    15781 atatcacgct atatggcccg gcgcagcggt tgggcgtcat cgcgtttaat ctgggtaaac
    15841 accacgctta cgacgtcggc agctttcttg ataattacgg tatcgcggta cgaacggggc
    15901 atcactgcgc aatgccgctc atggcctggt atggcgtgcc ggcaatgtgc cgggcttcgc
    15961 tggcgatgta taacacccat gaagaagtgg accgactggt ggcaggatta acgcgtatcc
    16021 accgcttatt gggataacag tgaggtttta tggctgcgct accggataaa gaaaaattgc
    16081 tgcgtaactt tacgcgttgc gctaattggg aagagaaata tttatatatt attgagttgg
    16141 ggcagcgcct ggcggagtta aatccgcagg atcgcaatcc gcaaaatacg attcatggct
    16201 gtcagagcca ggtgtggatc gtgatgcggc gaaacgccaa tggcattatc gaattgcagg
    16261 gcgacagcga cgcggcgatc gttaaaggcc ttatggcggt ggtatttatt ttgtaccacc
    16321 agatgacggc gcaggatatt gtgcattttg atgtccggcc atggttcgaa aaaatggcgc
    16381 ttacgcaaca cctcacacct tctcgttctc aggggctgga agcaatgatt cgcgcaattc
    16441 gcgctaaggc cgccactctt agctaaacta tacagacagc gttctacctg atgtcaaatc
    16501 ctttgtcgga cggcgacgtc gctttatcca gagtggacag agcgtatatt ttgttgttct
    16561 gataagcgaa gcgctaccag ccgtcgcaga gggcatcacc aggaatacag gaggtttggt
    16621 atgaaacgtg cgtctttcat tacgctaact attatcggcg cgtatagcgc gttacaggca
    16681 gcctgggcgg ttgattatcc attaccgcca gaaggcagcc gtcttattgg tcagaatcaa
    16741 acctataccg tacaggaagg tgataaaaac ctgcaggcta tcgcccggcg ttttgatacg
    16801 gcggcgatgc tcatccttga agcgaacaat acgattgcgc cggtgcctaa gcccggtacg
    16861 ctaattacca ttccctcgca gatgctattg ccggatgcgc ccagggaagg cgtcatcgtc
    16921 aacctcgcgg agctacggtt gtattttacc cgccgggaga aaaccgcgtt caggtgtatc
    16981 ccatcggcat cggtttgcag ggactggaaa ctcccgtcat ggacacccgg atagggcaaa
    17041 agatccccaa cccgacgtgg acgccgacgg caggcatacg ccaacgttcg cttgagcggg
    17101 ggatcacgct gccgccggtg atccctgccg ggccaaataa cccgctggga cgctatgcgc
    17161 tgcgtctggc gcacggtaat ggggaatatc tcattcatgg caccagcgcg ccggatagcg
    17221 taggtctgcg cgtgagttcc ggttgcattc gcatgaacgc gccggacatc aaagcgttat
    17281 ttgcgcaggt cagaacgggg atgccggtaa aagtgattaa ccagccggtg aaattctctg
    17341 tcgagccgaa tggcattcgt tatgtagagg tacacaggcc gctatcgccg gaagaagagc
    17401 aaaacgtgca gacgatgccc tatgtgttgc ctgcggaatt taccgcgttc agaaacgcgc
    17461 aaggggtgga tagtcgcctg gtcgataagg cgctataccg gcgagccggg tatcctgtca
    17521 gcgtgagcgc cggacagacg ccagcggtaa atacgaccgc agtcgaatcc gctcagaacg
    17581 gttttgtcgg ggaagagggg caaacgcgcg cgacgcagta gccttcgcag taaatgacgg
    17641 acaaaaaaat ggcgcacgat gtgcgccatt ttatatcatg cgtcaaatca tttacagatg
    17701 cggaatactt tgttgtccag acgttggtta gcgcgagctg cgtcgtcttt agcagcctga
    17761 acgtcggaac gcattgcatt tacgtcatta ctcagttgat caactttagc gctcagcgtc
    17821 tgtacatcgg aagacaactg atcgatttta gcgttgctgg aacaacctgc cagtaacgtg
    17881 gaacccagaa ctactgcacc taagatcagt ttgttagtgc ggttcataac aataacctta
    17941 tattttgtgt gg
//
LOCUS       DAJVBX010000082        17924 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.082, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000082 DAJVBX010000000
VERSION     DAJVBX010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 17924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17924
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.082"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..199
                     /locus_tag="OPV72_002393"
     CDS             <1..199
                     /locus_tag="OPV72_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="fimbriae biosynthesis transcriptional regulator
                     FimZ"
                     /protein_id="HCR9914668.1"
                     /translation="HDMPLSNREVTVLRYLANGMSNKEIAEQLLLSNKTISAHKANIF
                     SKLGLHSIVELIDYAKSHELL"
     gene            complement(245..763)
                     /gene="sfmF"
                     /locus_tag="OPV72_002394"
     CDS             complement(245..763)
                     /gene="sfmF"
                     /locus_tag="OPV72_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria assembly protein"
                     /protein_id="HCR9914669.1"
                     /translation="MILRRVFIAIGCVLLSPLSQANSSLGEVNIELRGNVVDFTCAVV
                     AGDSNKSVNLGTWPTKQLHVAGDATQPVAFSLKLEGCPPGSASITFSGTPAPGTALLA
                     LADTAMAQKLAIEIRDGDQRRLPLEQASKAVDIDNNGNATLKFYANYIALADGVQPGL
                     ANADATFLINYN"
     gene            complement(773..1780)
                     /gene="fimH"
                     /locus_tag="OPV72_002395"
     CDS             complement(773..1780)
                     /gene="fimH"
                     /locus_tag="OPV72_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrin D-mannose specific adhesin FimH"
                     /protein_id="HCR9914670.1"
                     /translation="MKIYSALLLAGTALFFTHPALATVCRNSNGTATDIFYDLSDVFT
                     SGNNQPGQVVTLLKKSDWCGVNATCPAGTTVNYTYRSYVSELPVQSTEGNFKYLKLND
                     YLLGAMSITDSVAGVFYPPRNYIRMGVDSNVSQQKPFGVQDSKLVFKLKVIRPFINIV
                     TIPRQTMFTVYVTTSTGDALSTPVYTISYSGKVEVPQNCEVNAGQVVEFDFGDIGAPL
                     FSQAGAGNRPQGVTPQAKTIAIKCTNVAAQAYLSMRLEAEKASGQAMVSDNPDLGFVV
                     ANSNGTPLTPNNLSSKIPFHLDDNAAARVGIRAWPISVTGNKPAEGPFTARGYLRVDY
                     D"
     gene            complement(1795..4407)
                     /locus_tag="OPV72_002396"
     CDS             complement(1795..4407)
                     /locus_tag="OPV72_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis usher protein"
                     /protein_id="HCR9914671.1"
                     /translation="MKKTTWFAGRFPGYVSPLSGVALSVLAALCPLTSRGESYFNPAF
                     LSADTASVADLSRFEKGNHQPPGIYRVDIWRNDEFVATQDIRFEAGAVGAGDKSGGLM
                     PCFTPERIKRLGVNTAVFPVSDKGVDTTCIHLPEKIPGAEVAFDFASMRLNISLPQAS
                     LLNSARGYIPPEEWDEGIPAALINYSFTGSRGTDSDSYFLSLLSGLNYGPWRLRNNGA
                     WSYSKGDGYHSQRWNNIGTWVQRAIIPLKSELVMGDSHTGNDVFDSVGFRGARLYSSD
                     NMYPDSLQGYAPTVRGIARTAAKLTIRQNGYVIYQSYVPPGAFAITDLNPTSSSGDLE
                     VTVDEKDGSQQRYTVPYSTVPLLQREGRVKYDLVAGDFRSGNSQQSSLFFFQGTVIAG
                     LPAGLTAYGGTQLADRYRAVVVGAGQNLGDWGAVSVDVTHARSQLADDSTHQGQSLRF
                     LYAKSLNNYGTNFQLLGYRYSTRGFYTLDDVAYRSMEGYDYEYDSDGRRHKVPVAQSY
                     HNLRYSKKGRFQVNISQNLGNYGSLYLSGSQQNYWNTADTNTWYQLGYASGWQGISYS
                     LSWSWSESVGISGADRILAFNMSVPFSVLTGRRYARDTILDRTYATFNANRNRDGDNS
                     WQTGVGGTLLEGRNLSYSVTQGRSSTNGHSGSASASWQATYGTLGVGYNYDRDQHDYN
                     WQLSGGVVGHTDGITFSQPLGDTNVLIKAPGAKGVRIENQTGVKTDWRGYAVMPYATV
                     YRYNRVALDTNTMDNHTDVENNVSSVVPTEGALVRAAFDTRIGVRAIITARLGGRPLP
                     FGAIVRETASGITSMVGDDGQIYLSGLPLKGELFIQWGEGKNARCIAPYALAEDSLKQ
                     AITIASATCIRPSS"
     gene            complement(4438..5130)
                     /gene="fimC"
                     /locus_tag="OPV72_002397"
     CDS             complement(4438..5130)
                     /gene="fimC"
                     /locus_tag="OPV72_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria chaperone FimC"
                     /protein_id="HCR9914672.1"
                     /translation="MLNSIKLGFIVLLTLFTSLNVQAAGGIALGATRVIYPSAAKQTS
                     LAISNSDTQERYLVNSWIENNAGQKEKTFIVTPPLFVSEPKSENTLRIIYAGQPLPED
                     RESLFWMNVKAIPSVDKSHIEGKNVLQLAILSRIKLFVRPANLPQTPEDAPTLLKFSR
                     VGNHLKITNPSAYYLTLVNISVGAKKIDNVMIAPKSDMQIPLPTGAQGSVTFQTVNDY
                     GALTSATTASLG"
     gene            complement(5174..5707)
                     /gene="fimI"
                     /locus_tag="OPV72_002398"
     CDS             complement(5174..5707)
                     /gene="fimI"
                     /locus_tag="OPV72_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein subunit FimI"
                     /protein_id="HCR9914673.1"
                     /translation="MIRKGAALVGLVLMSPVIAQPVMVESGRVHLRGQLVNGGCAVAT
                     ESQDLRVLMGQYRTNAFTGPGSFAPVSVPFSLRLISCSAEVWRHVGIAFAGVTPAEDP
                     HVFLASGEGIGNAGIGLALFDDQQRQIIPNTLPLHYAPILTSEMTLHFTARYRAISEN
                     MTPGRIHSEVWFTLVYP"
     gene            complement(5782..6336)
                     /gene="fimA"
                     /locus_tag="OPV72_002399"
     CDS             complement(5782..6336)
                     /gene="fimA"
                     /locus_tag="OPV72_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459538.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein subunit FimA"
                     /protein_id="HCR9914674.1"
                     /translation="MKHKLMTSTIASLMFVAGAAVAADPTPVSVSGGTIHFEGKLVYA
                     ACAVSTKSADQTVTLGQYRTASFTAIGDTTAQVPFSIVLNDCDPKVAATAAVAFSGQA
                     DNTNTNLLAVSSADNSTTATGVGIEILDNTSSPLKPDGATFSAKQALVEGTNTLRFTA
                     RYKATAAATPGQANADATFIMKYE"
     gene            6883..7749
                     /gene="folD"
                     /locus_tag="OPV72_002400"
     CDS             6883..7749
                     /gene="folD"
                     /locus_tag="OPV72_002400"
                     /EC_number="1.5.1.5"
                     /EC_number="3.5.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase
                     FolD"
                     /protein_id="HCR9914675.1"
                     /translation="MAAKIIDGKTIAQQVRSEVAQKVQARVAAGLRAPGLAVVLVGSN
                     PASQIYVASKRKACDEVGFVSHSYDLPETTSEAELLALIDTLNADNTIDGILVQLPLP
                     AGIDNVKVLERIAPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTYGL
                     NAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKDLRHHVEHADLLIVAVGKPGFIPG
                     EWIKEGAIVIDVGINRLENGKVVGDVVFDEAAARASYITPVPGGVGPMTVATLIENTL
                     QACIEYHDPQGK"
     gene            7751..7963
                     /gene="ybcJ"
                     /locus_tag="OPV72_002401"
     CDS             7751..7963
                     /gene="ybcJ"
                     /locus_tag="OPV72_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated protein YbcJ"
                     /protein_id="HCR9914676.1"
                     /translation="MATFSLGKHPHVELCDLLKLEGWSESGAQAKIAIADGLVKVDGA
                     VETRKRCKIVAGQTVSFEGQSVNVVA"
     gene            8047..8595
                     /locus_tag="OPV72_002402"
     CDS             8047..8595
                     /locus_tag="OPV72_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001728132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HCR9914677.1"
                     /translation="MPTVITHAAVPLCLGAGLGLKVIPPRLLFAGVVLAMLPDADVLA
                     FKFGVAYGNVFGHRGFTHSLLFAFVLPLLCVLAGRRWFRAGQVRCWLFLTVSLLSHSL
                     LDSITTGGKGVGWLWPWSDERFFAPWQVIKVAPFALSSYITPYGHQVIVSELLWVWLP
                     GGVLIGILGWHRWRIGDEKRTR"
     gene            complement(8686..10071)
                     /gene="cysS"
                     /locus_tag="OPV72_002403"
     CDS             complement(8686..10071)
                     /gene="cysS"
                     /locus_tag="OPV72_002403"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HCR9914678.1"
                     /translation="MLKIFNTLTRQKEEFKPIHAGEVGMYVCGITVYDLCHIGHGRTF
                     VAFDVVARYLRFLGYKLKYVRNITDIDDKIIKRANENGESFVALVDRMIAEMHQDFDA
                     LNILRPDSEPRATHHIQEIIELTRTLIEKGHAYVADNGDVMFDVPTDPTYGQLSRQDL
                     EQLQAGARVDVVDVKRNPMDFVLWKMSKEGEPSWPSPWGEGRPGWHIECSAMNCKQLG
                     NHFDIHGGGSDLMFPHHENEIAQSTCAHDGEYVNYWMHSGMVMVDREKMSKSLGNFFT
                     VRDVLKYYDAETVRYFLMSGHYRSQLNYSEENLKQARASLERLYTALRGTDKSAAPAG
                     GEAFEARFVEAMNDDFNTPEAYSVLFDMAREVNRLKGEDMTAANAMASHLRKISGVLG
                     LLEQEPDVFLQSGAQADDGEVAEIEALIQQRLDARKAKDWAAADAARDRLTEMGIILE
                     DGPQGTTWRRK"
     gene            10244..10738
                     /gene="ppiB"
                     /locus_tag="OPV72_002404"
     CDS             10244..10738
                     /gene="ppiB"
                     /locus_tag="OPV72_002404"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase B"
                     /protein_id="HCR9914679.1"
                     /translation="MVTFHTNHGDIVIKTFDDKAPETVKNFLDYCREGFYNNTIFHRV
                     INGFMIQGGGFEPGMKQKATKEAIKNEANNGLKNTRGTLAMARTQAPHSATAQFFINV
                     ADNDFLNFSGESLQGWGYCVFAEVVEGMDVVDKIKGVATGRSGMHQDVPKEDVIIENV
                     TVSE"
     gene            10741..11463
                     /gene="lpxH"
                     /locus_tag="OPV72_002405"
     CDS             10741..11463
                     /gene="lpxH"
                     /locus_tag="OPV72_002405"
                     /EC_number="3.6.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-2,3-diacylglucosamine diphosphatase"
                     /protein_id="HCR9914680.1"
                     /translation="MATLFIADLHLQTEEPAIVAGFLRFLAVEARQADALYILGDLFE
                     AWIGDDDPNPLHREMAVAIKSLVDSGVPCFFIHGNRDFLIGKRFARESGMTLLPQEKV
                     LDLYGRNVLIMHGDTLCTDDAGYQAFRAKVHNPWVQRPFLTLPLFIRRRIAARMRAGS
                     KAANSSKSLDIMDVNAQTVVAEMEKHRVQWLIHGHTHRPAVHELSANGQPAFRVVLGA
                     WHHEGSMVKVTPDNVELIAFPL"
     gene            11581..12090
                     /gene="purE"
                     /locus_tag="OPV72_002406"
     CDS             11581..12090
                     /gene="purE"
                     /locus_tag="OPV72_002406"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HCR9914681.1"
                     /translation="MSSRNNPARVAIVMGSKSDWATMQFAAEIFEILDVPHHVEVVSA
                     HRTPDKLFSFAETAEENGYQVIIAGAGGAAHLPGMIAAKTLVPVLGVPVQSAALSGVD
                     SLYSIVQMPRGIPVGTLAIGKAGAANAALLAAQILATHDSALHRRIADWRKAQTDEVL
                     ENPDPRGTL"
     gene            12087..13154
                     /gene="purK"
                     /locus_tag="OPV72_002407"
     CDS             12087..13154
                     /gene="purK"
                     /locus_tag="OPV72_002407"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HCR9914682.1"
                     /translation="MKQVCVLGNGQLGRMLRQAGEPLGIAVWPVGLDAEPTAVPVQQS
                     VITAEIERWPETALTRELARHPAFVNRDVFPIIADRLTQKQLFDKLGLATAPWQLLSS
                     ADEWSGIFDRLGELAIIKRRVGGYDGRGQWRLRADETGQLPDDCYGECIVERGIHFSG
                     EVSLVGARAHDGSTVFYPLTHNLHQDGILRTSVAFPQANAEQQEQAESMLSAIMQALN
                     YVGVMAMECFITPEGLLINELAPRVHNSGHWTQNGASISQFELHLRAITGLPLPAPVI
                     NAPSVMINLIGSELNYDWLKLPLVHLHWYDKAVRPGRKVGHLNLTDSDTSRLSATLEA
                     LSPLLPGEYASGIIWAQSKLK"
     gene            complement(13195..14088)
                     /locus_tag="OPV72_002408"
     CDS             complement(13195..14088)
                     /locus_tag="OPV72_002408"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HCR9914683.1"
                     /translation="MKTLVVALGGNALLQRGEALTAENQYRNIADAVPALARLARSYR
                     LAIVHGNGPQVGLLALQNLAWKAVEPYPLDVLVAESQGMIGYMLAQRLALEPDMPPVT
                     AVLTRIKVSADDPAFLEPEKFIGPVYSPEEQMALEATYGWHMKRDGKYLRRVVASPAP
                     RQIIESTAIELLLKEGHVVICSGGGGVPVAGEGEGVEAVIDKDLAAALLAEQIAADGL
                     IILTDADAVYEHWGTPQQRAIRQASPDELAPFAKADGAMGPKVTAVSGYVKRCGKPAW
                     IGALSRIDDTLAGRAGTCICL"
     gene            complement(14092..14901)
                     /locus_tag="OPV72_002409"
     CDS             complement(14092..14901)
                     /locus_tag="OPV72_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2877 domain-containing protein"
                     /protein_id="HCR9914684.1"
                     /translation="MKRIHPLMASRQSADYRQPWQMSGVWRRSINFVAKSGELLTLHR
                     RGSGFSPGGWILRGGDFDALRDVLTDGEKPQLTAAGIQIGEFLLCEPERRCSLRVPRY
                     LASPRLNATYMQRSEETGLFGPLTVAAAQPLCPELRQFCHCFQSALAGAATDWRLWLG
                     KGPGLTPSHEDTLTGMLLAAWYFGAIDERAGRNFFAQSGSLDRATTLVSVSYLRYAAM
                     GYFASPLLHFIHALRRDARTETAIDGLLALGHTSGADTLLGFWLGQQIVKG"
     gene            complement(14913..16172)
                     /locus_tag="OPV72_002410"
     CDS             complement(14913..16172)
                     /locus_tag="OPV72_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1116 domain-containing protein"
                     /protein_id="HCR9914685.1"
                     /translation="MFTSVAQANAAVIEQIRRARPHWLDVKPASSLISVLNQGKTLLH
                     AGPPMRWQEMTGPMKGACIGACLFEGWAKDEMSALALLEQGKVNFIPCHHVNAVGPMG
                     GITSASMPMLVVENITDGNRAYCNLNEGIGKVMRFGAYGEDVQQRLRWMRDVLMPVLS
                     AALGRLERGLDLTAMMAQGITMGDEFHQRNIASSALLMRTLAPHIARLQHDKQQIAEV
                     MDFLSVTDQFFLNLAMAYCKAAMDAGAQIRAGSIVTAMTRNGDMFGIRVSGLGDRWFT
                     APVNTPQGLFFTGFSQDQANPDMGDSAITETFGIGGAAMIAAPGVTRFVGAGGMEAAK
                     SVSEEMAEIYLERNMQLQIPGWDFQGACLGLDIRRVVETGITPLINTGIAHKEAGIGQ
                     IGAGTVRAPLACFEQALEALAESMGVS"
     gene            complement(16182..17846)
                     /locus_tag="OPV72_002411"
     CDS             complement(16182..17846)
                     /locus_tag="OPV72_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase FdrA"
                     /protein_id="HCR9914686.1"
                     /translation="MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKS
                     LLETTGFWHDDFHGATPNDICVAIRTEAVDDGITQVIVRQLEEALQQLAQGSSGSQSL
                     IQVRRWESACQKLPEANLALVSVAGEYAAELAEQALARSLNVMIFSDNVTLDDEIRLK
                     RRARDKGLLVMGPDCGTAMIANTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGE
                     GITHAIGLGGRDLSAEVGGISALTALDILSADEKSQVLAFVSKPPADAVRQHIIAAMK
                     ATGKPVVALFLGFSSPVAREENVWFASTLDEAARLACLLSRVTSQRKEMVSTGGVIRG
                     LYTGGTLAAEAAGLLAGYLGVATDTEHHHGMMLDADGHQIIDLGDDFYTVGRPHPMID
                     PALRNQLIAGLGAQPQVRVLLVDVVIGFGATADPAASLIQAWQKACAARASDQPLFAI
                     ATVTGTERDPQCRSQQIAALEDAGITVVDSLPEATLLAAELIRPTLSSTHPSAPRLLE
                     AVAVINAGLRSFALDLQAAGMPVVHYQWAPVAGGNKKLARLLERLQ"
BASE COUNT         4038 a         5168 c         4655 g         4063 t
ORIGIN      
        1 ccatgatatg ccactttcta accgcgaagt taccgtgctg cgctatctgg ccaatggaat
       61 gtctaacaaa gaaattgccg agcaactttt attgagtaac aagactatca gcgcgcataa
      121 ggccaatata ttttctaaac ttggccttca ctctatcgtt gagcttatcg attacgccaa
      181 atcacacgaa ttattgtaaa tgtactcccg gcgaattatc gttcgggagc caaaataacg
      241 gacactaatt gtaattgatc aggaaggtcg catccgcgtt agcaagaccg ggctgcacgc
      301 catcggctaa ggcgatatag ttcgcataga atttcagggt agcattgccg ttgttgtcaa
      361 tatcgacggc cttgctggcc tgttcaagtg gcaatcgacg ttgatcgcca tcgcgaattt
      421 caatcgccag tttttgcgcc attgccgtat cagcaagcgc cagtaatgcc gtgccgggcg
      481 ctggcgtccc ggaaaacgtt atagacgccg aacctggcgg gcagccttca agttttaggc
      541 taaaggctac cggttgcgta gcgtccccgg cgacgtgaag ctgttttgtc ggccaggtgc
      601 cgaggttaac cgacttgtta ctgtcgcccg caaccacggc gcaggtaaaa tccaccacgt
      661 taccgcgcag ttcaatattc acttcgccca gagatgagtt ggcctgactc agcgggctta
      721 acaaaacaca accgatagcg atgaaaacgc gccgaagaat cattatgcct ccttaatcat
      781 aatcgactcg tagatagccg cgcgcagtaa acggcccttc cgccggttta ttccccgtca
      841 cgctgatcgg ccaggcgcga atacctacgc gagcggcggc gttatcatca agatgaaacg
      901 gaattttact cgacaaatta ttgggtgtga gcggcgtacc gttgctatta gcaaccacaa
      961 agcctaaatc cgggttatcg gacaccatcg cctgccctga ggccttttcg gcttcaagcc
     1021 gcatcgataa ataggcttgc gccgcgacgt tggtacattt gatagcgata gttttcgctt
     1081 gcggcgtgac gccttgcgga cgattacccg ctcccgcctg actaaataac ggcgcgccga
     1141 tatcgccgaa atcaaactcc acgacctgtc cggcattcac ttcacagttt tgcggtactt
     1201 ccactttgcc gctgtagcta atggtataca ccggcgtgct caacgcgtcg ccggtagagg
     1261 tcgtcacata gacggtaaac attgtctggc gggggatcgt cactatatta ataaaaggcc
     1321 gtatcacttt taatttaaaa accagctttg agtcctgcac gccaaacggc ttttgctgcg
     1381 acacgttaga gtcgacgccc atgcgaatat agttacgggg cggataaaat acgccagcga
     1441 cactatcggt tatgctcatc gcgcccagaa ggtagtcatt caacttgagg tatttaaaat
     1501 ttccttcggt gctttgtacc ggtaattctg atacatagct tcggtaggta taattcaccg
     1561 ttgtccccgc cgggcacgtc gcgtttacgc cgcaccaatc tgattttttc agcagcgtca
     1621 ccacctgtcc cggctgatta ttgccgctgg tgaaaacatc tgacaggtca taaaagatat
     1681 cggtcgccgt cccgtttgaa ttacggcaaa ccgtcgccag cgcgggatgg gtgaaaaaga
     1741 gtgcggtccc cgccagcaat agcgctgagt atattttcat ctctattttt ccttttatga
     1801 cgacggacgg atacaggtcg cgctggctat cgtaatcgcc tgcttcaggc tatcctccgc
     1861 cagggcgtaa ggggcgatac aacgcgcgtt tttcccctct ccccactgga tgaacagttc
     1921 accttttagc ggcaagccgc tcagataaat ttgtccgtca tcgccgacca tgctggtaat
     1981 gccgctggcg gtttctcgta ctatcgcgcc aaacggtaac ggacgtccgc caagcctcgc
     2041 ggtaatgatt gcccttacgc ctatccgcgt atcaaaagca gcccgcacca gcgcgccttc
     2101 agtcggcacc acgctgctga cgttattttc gacatcggta tggttgtcca tcgtgttggt
     2161 atctaacgcg acgcggttat agcgatatac cgtggcgtag ggcattaccg catagccccg
     2221 ccagtccgtt ttcacgccgg tctggttttc gatgcgcacg cctttcgctc ccggcgcttt
     2281 aatcaagaca ttggtatcgc ccaacggttg gctaaacgta ataccatccg tatgaccgac
     2341 cacgccgccg gaaagttgcc agttatagtc atgctgatcg cgatcgtagt tatatcccac
     2401 gcccagcgtg ccatacgtcg cctgccagct agcgctggcg ctgccgctat gaccattggt
     2461 actgctacgc ccctgcgtca cgctgtagct cagattacgt ccttccagaa gcgtgccgcc
     2521 cacaccggtc tgccagctat tgtcgccgtc gcggttgcgg ttggcgttaa acgtggcata
     2581 agtacgatca agaatagtgt cgcgcgcata gcgccgtccg gtcagaacgc taaacggaac
     2641 ggacatattg aatgccagaa tgcggtcggc gcctgagatc cccaccgact cgctccacga
     2701 ccatgacagc gaataactta tgccttgcca tccactggcg tatcccagtt gataccaggt
     2761 attggtatcc gccgtattcc agtaattttg ttgactgccg gaaagataca gtgacccgta
     2821 attccccaga ttttgcgaaa tattgacctg aaagcggcct tttttgctgt agcggagatt
     2881 gtggtagctc tgcgccaccg gcactttatg gcggcgtccg tcgctatcgt attcgtagtc
     2941 gtacccttcc atactgcggt atgccacatc atccagggtg taaaatccgc gcgtggaata
     3001 gcggtaaccc agcaattgaa aattagtccc gtaattattc agcgatttgg cgtacagaaa
     3061 acgcaacgat tgcccctgat gggtgctgtc atctgccagt tggctacgcg catgtgtgac
     3121 atcgaccgac acggcccccc agtcacccaa attttgcccc gccccgacca ccacagcacg
     3181 gtaacgatcg gcaagttgcg taccgccgta agccgtcagc cccgcaggca ggccggcaat
     3241 caccgttccc tggaaaaaga atagcgaaga ctgctgacta ttgccgctgc gaaaatcccc
     3301 ggccaccagg tcatacttca ccctgccctc acgctgcaat agcggaacgg tagagtaagg
     3361 caccgtgtaa cgttgttggc taccgtcttt ttcatctacc gtcacctcaa ggtcgccgct
     3421 ggaagaggta ggattaagat cggtaatcgc aaacgcgccc ggcggcacat agctttggta
     3481 gataacatac ccgttctgtc gtatcgtcag ctttgccgcc gtccgggcga tccctctgac
     3541 cgtgggggcg tagccctgca ggctatcggg atacatattg tcagaagagt acagccgcgc
     3601 tccgcgaaag ccgacgctgt cgaaaacatc gttcccggta tggctgtccc ccatgaccag
     3661 ttcgcttttt agcggaatga tggcgcgctg tacccaggtg ccaatgttgt tccagcgttg
     3721 cgaatgatag ccgtcccctt tcgaatagct ccaggctccg ttattacgca gccgccaggg
     3781 gccatagttc aacccgctca gcagactcaa aaaatagcta tcgctgtctg ttccgcggct
     3841 accggtaaaa ctgtaattaa tgagtgcggc gggtatccct tcatcccact cttccggcgg
     3901 gatatagcca cgcgcgctgt tgagcaatga cgcctgcggc aagctaatgt ttaagcgcat
     3961 cgacgcgaaa tcgaacgcga cctccgcgcc cgggattttc tcaggaaggt gaatacacgt
     4021 ggtatcgacg cctttatctg agacagggaa caccgcggta ttcacgccca gccgtttaat
     4081 cctctccggt gtaaaacaag gcatcaggcc gccggattta tcgccggcgc ccacggcgcc
     4141 cgcctcaaaa cgaatatcct gcgtcgctac gaattcgtcg ttacgccaga tatccacccg
     4201 gtaaataccg ggaggctgat gattaccttt ttcaaagcga gataaatccg ccacggacgc
     4261 ggtatccgcc gacaaaaacg cagggttgaa ataactttcg ccgcggctcg tcagcggaca
     4321 cagagctgcc aacaccgaca gcgccacgcc gcttaacggt gatacatagc cgggaaatcg
     4381 ccctgcaaac caggttgtct tcttcatcgt gttctcgtgt ggcttcacgc tctctgctta
     4441 accgagactg gctgttgtcg ccgacgtcaa tgcgccgtaa tcattgacgg tctgaaatgt
     4501 cacgctgccc tgcgcgccag tcggtaaggg aatttgcatg tcgctttttg gcgcgatcat
     4561 cacgttatca atctttttcg cacccacgct gatattgacc agcgtgaggt aataagcaga
     4621 tgggttggtt atcttgagat ggttgccgac acgggaaaat ttcagcaagg tcggcgcgtc
     4681 ttccggcgtc tgcggcaaat tcgccggacg cacgaacagt ttgatgcgcg acagaatcgc
     4741 cagttgcaga acgttttttc cttcaatatg acttttatcg accgacggga tggctttcac
     4801 gttcatccag aataacgact cccgatcctc gggtagcggt tgcccggcgt agataatacg
     4861 cagcgtgttt tcacttttgg gctcgctgac gaataaaggc ggcgtaacga taaacgtttt
     4921 ttctttctgc ccagcgttat tttcgatcca tgaattgacg aggtaacgtt cttgagtatc
     4981 gctattactg attgccagag aagtctgttt cgccgccgag ggataaataa cacgcgtggc
     5041 gcctaatgca atcccccccg ccgcctgtac gttcagcgaa gtaaataacg tgagaagaac
     5101 aataaatcct aattttatac tattcagcat ggtaaaaaat accttttgca ttgagtcacg
     5161 tcggcaagaa aattcatggg taaaccagcg taaaccacac ttctgaatga attcgtcccg
     5221 gcgtcatatt ttctgaaatt gcccgatagc gggcggtaaa atgcaaagtc atttctgacg
     5281 ttaaaatggg cgcgtaatga agcggtaacg tgttaggtat gatttgccgc tgctggtcat
     5341 caaataacgc caggccgatt ccggcattac cgataccttc gccgctggcc agaaaaacat
     5401 ggggatcttc cgcaggcgta acgccggcaa acgcaatgcc gacatgacgc cagacctccg
     5461 cgctacagga gattaaccgt aacgaaaatg gaacgctgac gggagcgaag ctgccaggac
     5521 cggtaaacgc attcgtgcgg tactgtccca tcagtacgcg caaatcctgg ctttcagtgg
     5581 cgacagcgca gccgccattg accagttgtc cgcgcaggtg aacacgcccg ctctctacca
     5641 ttaccggctg cgcaatgacg ggcgacatca aaacaagccc cactagcgcc gcgcctttcc
     5701 ttatcatctg ctatgttctc ttttatcccc gatagcctct tccgttgaga cgcctccctt
     5761 ccctggcgtt ccctgacggg attattcgta tttcatgata aaggtggcgt cggcattagc
     5821 ctggcctggc gtcgcggcgg cggttgcctt atagcgtgcg gtaaaacgca gcgtattggt
     5881 gccttcaacc agcgcctgct tcgccgagaa ggtcgcgccg tccggcttca acggtgagga
     5941 ggtgttatca agaatctcaa tcccgacgcc ggttgcggta gtgctattgt ccgcagagga
     6001 gaccgccagc aaattagtgt tggtgttatc tgcctgacca gagaaagcca cggcagcggt
     6061 ggccgccact tttggatcgc agtcattcag gacgatggag aaaggcacct gcgcggtcgt
     6121 atcaccaatc gccgtaaagc tggcggtacg gtattgaccc agcgtcaccg tttgatcggc
     6181 ggatttagtg ctaacggcac aggctgcata aaccagttta ccttcgaaat gaatagtacc
     6241 gccgctcacg ctcaccggag taggatcagc cgcaaccgct gcgccagcga caaacatcag
     6301 actcgcaata gtagaggtca ttaatttatg tttcatggat tttccttgaa ttacacacac
     6361 ccggtttcga tatcctgtcg gctccgtttg aattattatc gacatagcat gtcagaaaag
     6421 ttatctctgc atcctgtaaa gatagatatc gcagattaat tagttttctg tttctcccct
     6481 gagtatcaga cgcagtaatt aatctttgcg aatatgacat ttcgtcacgg taataaatta
     6541 aacatttcgc taaataaaaa atagccgcaa actcttttaa tgacctaagc taattcttat
     6601 ttggatataa gaagggtcta atcttatttt gtataaaatg tcgcattatg ccgcccgatg
     6661 ctattaacgg cgagggatta cggtaaccat agccagggtg atgaattgtt tctttttggt
     6721 taatcatggc gcgcttactg gtcacgtctc agtatcgtca acggacgggg gagacgtcgc
     6781 gtttgcatcg gaaacacaaa cgttaactga cagcgaggcc cgcttctgac aaaatagcgt
     6841 tatccccttt gacttgaagt aacagatgga atcttctctc tgatggcagc aaagattatt
     6901 gacggtaaaa cgattgcgca gcaggtgcga tctgaggttg ctcaaaaagt tcaggcacgc
     6961 gtcgcagcgg gtcttcgcgc tcccggcctg gctgtggtgt tggtcggcag caatccggcc
     7021 tcacagattt atgtcgcaag caaacgtaaa gcgtgcgacg aagtgggatt cgtctcccac
     7081 tcctatgacc tgccagaaac caccagcgaa gccgaactgc tggcgcttat cgatactctg
     7141 aatgcagata acacgatcga tggtattctg gtgcagttgc ctttaccggc aggtatcgac
     7201 aacgttaaag tgctggagcg tatcgcgccg gataaagacg tagacggttt tcatccttat
     7261 aacgtcggtc gtctgtgcca gcgtgcgccg cgcctgcgtc cctgtacgcc ccgcggtatt
     7321 gtgaccctgc ttgagcgcta caatattgat acctacggcc tgaatgcggt ggtcattggc
     7381 gcgtctaata tcgttggacg cccgatgagc atggagctgc tgctggctgg ctgtacgact
     7441 accgttacgc accgctttac caaagatctg cgtcatcatg tcgagcatgc tgatttgctc
     7501 attgtcgccg ttggtaaacc gggctttatt cccggcgaat ggattaaaga aggcgcaatt
     7561 gtgattgatg tcggtattaa ccgtctggaa aatggcaagg tcgttggcga cgtcgtgttt
     7621 gacgaagccg cggcgcgcgc gtcatacatc acgccagtac cgggcggcgt cggcccgatg
     7681 acggtcgcca cgcttatcga aaacacgctg caggcgtgca ttgaatatca cgatccacaa
     7741 ggaaaataac atggcgacat tctctttagg caagcacccg cacgtcgagc tgtgcgatct
     7801 gctcaagctg gaaggctgga gcgaaagcgg cgcgcaggcg aaaatcgcca ttgccgacgg
     7861 gttggtgaag gttgatggcg cggttgaaac gcgtaaacgc tgcaaaattg tcgccgggca
     7921 aaccgttagc ttcgaaggcc aaagtgtgaa cgtcgtggcc tgattacgct gtcttttcag
     7981 ataatcatcc acttaatcct ctacgttcca actgctagca tggctatttc cctgtgaacg
     8041 atcgctatgc ctaccgttat cacccacgcc gccgttcctc tgtgtcttgg cgcaggctta
     8101 ggcctgaaag ttatccctcc tcgcctgctg tttgccggtg ttgtgctggc gatgctcccc
     8161 gatgctgacg tgctggcctt taaatttggc gtcgcctacg gcaacgtgtt cggccatcgc
     8221 ggatttaccc actctttact tttcgcattc gtcctccccc tgttgtgcgt actcgcggga
     8281 cgacgatggt ttcgagcggg gcaggtgcgc tgctggctgt ttttaaccgt ttcattgttg
     8341 tcgcacagcc tgctggattc gataaccacg ggtggtaaag gcgtcggatg gctgtggccg
     8401 tggtcggatg aacgtttctt tgcaccctgg caggtgatta aagtcgcgcc gtttgcgctt
     8461 tcaagctaca tcacgccgta tgggcatcag gtgattgttt cggagctgct atgggtgtgg
     8521 ctaccggggg gcgtgctaat agggatattg ggctggcaca gatggcgtat aggggacgaa
     8581 aagcggactc gctaatgtcg gacggcgcta cgcttacccg acctgtagat ttcatctcag
     8641 gtaggccgga taagacgccc tgcgtcttat ccggcaatac ggcaattact tacgtcgcca
     8701 ggtggtgccc tgcgggccat cttccagaat aatacccatt tcagtgagac gatcgcgcgc
     8761 cgcgtccgcc gccgcccagt ctttcgcttt acgggcatcc agacgctgtt gaatcaaggc
     8821 ttcaatttcc gcaacttcac cgtcatccgc ctgcgcgccg ctttgcagga aaacatccgg
     8881 ctcctgctcc agcagtccca gcacgccgga aatcttccgc agatgagacg ccatcgcatt
     8941 cgcggcggtc atatcttcgc ccttcagacg gttgacttca cgcgccatgt caaacaggac
     9001 ggagtaggct tccggcgtat tgaaatcgtc attcatcgcc tccacgaaac gcgcttcaaa
     9061 cgcttcgccg cccgccgggg ccgctgattt atccgttcca cgcaatgcag tgtataaccg
     9121 ctccagcgag gcgcgcgcct gcttgaggtt ctcttcgctg tagttcagtt ggctacggta
     9181 atgcccggac atcaggaagt agcgcacggt ttccgcatcg tagtatttca gcacgtcgcg
     9241 cacggtaaag aagttgccca gcgatttgga catcttctcg cgatccacca tcaccatacc
     9301 ggagtgcatc cagtagttga cgtattcgcc gtcatgcgcg caggtagact gggcaatctc
     9361 gttttcatgg tgcgggaaca tcagatcgga accgccgccg tgaatatcaa aatggttgcc
     9421 caactgctta cagttcatcg ccgaacattc aatgtgccag cccggacgcc cttcgcccca
     9481 cggcgacggc cagctcggct cgccctcttt cgacattttc cacagcacga agtccatcgg
     9541 gttacgcttc acgtcaacga catccacgcg cgcgcccgcc tgaagctgct caagatcctg
     9601 acgggaaagc tgcccataag tcggatcggt cggtacatca aacatcacat cgccgttatc
     9661 cgccacatag gcgtgccctt tctcgattaa ggtgcgggtg agctcgataa tttcctgaat
     9721 atggtgcgtc gcacgcggct cgctgtccgg acgcagaata ttcagcgcgt cgaagtcctg
     9781 atgcatttcc gcaatcattc tgtcgaccag cgcgacaaaa ctttcgccgt tttcattggc
     9841 gcgtttaata attttatcgt cgatatcggt aatgttacgc acatacttca gcttataacc
     9901 gagaaaacgc aaatagcgcg cgacaacgtc aaaagcgaca aacgtgcgtc cgtggccaat
     9961 gtggcagaga tcgtaaacgg tgataccaca cacgtacatg ccgacttccc cggcatgaat
    10021 gggtttgaat tcctcttttt ggcgcgtcag tgtattaaaa atttttaaca tcgaagattc
    10081 cgtatagacg tgtgtgggta attaggtgtg tataatactc ataattcaac cttgaagcag
    10141 cacactttgc aaggtgatcg cagcttacga ttatgctata acaagcccct atatgtgccc
    10201 cattgcgggc taaagcacca ctctcttgga acaggatgca aaaatggtta ctttccacac
    10261 taatcacggc gatatcgtaa tcaaaacctt tgatgataaa gcgcctgaaa cagttaaaaa
    10321 cttcctggac tactgccgcg aaggttttta caacaacacc attttccacc gtgtgattaa
    10381 cggttttatg attcagggcg gcggctttga gccgggcatg aaacagaaag ccaccaaaga
    10441 ggcgatcaaa aacgaagcca acaatggtct gaaaaatacc cgtggtacgc tggcgatggc
    10501 gcgtactcag gcaccacatt cggctaccgc gcaattcttc atcaacgtgg cagacaacga
    10561 cttcctgaac ttctccggcg aaagtctgca gggctggggc tactgcgtct ttgcggaagt
    10621 cgtagaaggt atggacgtgg tagataaaat caaaggcgtc gccactggcc gtagcggtat
    10681 gcaccaggac gtaccaaaag aagacgtcat cattgaaaac gtgaccgtca gcgagtaatc
    10741 gtggcgacac tgtttattgc agacttgcat ctgcaaacgg aagaaccggc gatcgtcgcc
    10801 ggttttctgc gttttttagc cgtagaagcc cgtcaggccg acgcgctgta tattcttggc
    10861 gatctcttcg aggcttggat tggcgacgac gaccccaacc cgctacatcg tgaaatggcc
    10921 gttgccatta aatcgctggt tgattccggc gtcccttgct tctttattca tggtaatcgc
    10981 gacttcctga ttggcaaacg ctttgcccgc gaaagcggca tgacgctact accgcaggaa
    11041 aaagtgctcg acctgtatgg ccgcaatgtg ttgattatgc acggcgatac gctctgtacc
    11101 gatgatgccg gatatcaggc gtttcgcgcc aaagtccata atccgtgggt tcaacggccg
    11161 ttccttaccc tgccgctgtt tatccgccgc cgtatcgccg ccagaatgcg cgccggcagt
    11221 aaagccgcca acagcagcaa atcgctggat attatggacg tcaatgcgca gaccgtcgtc
    11281 gccgaaatgg aaaaacaccg cgtacagtgg ctgattcacg gtcacaccca ccgcccggcg
    11341 gtgcatgaac tttccgccaa cggccagccc gcgttccgcg tggtgttagg cgcatggcat
    11401 catgaaggtt caatggtaaa agtcacgccg gataacgtgg agttaatcgc cttccccctg
    11461 taaatgttcg tcgaatcgtc cgttacggcg cacacgcaac cgttttcctt gcctgattat
    11521 catgctattc tctgacacct caaaagcagc gtgtcccgca ccacaggagt tttaagacgc
    11581 atgtcttccc gcaataatcc ggcgcgtgtc gccatcgtga tggggtccaa aagcgactgg
    11641 gctaccatgc aattcgccgc cgaaattttt gaaattctgg atgtcccgca ccatgtagaa
    11701 gtggtttccg cccatcgcac ccccgataaa ctgttcagct tcgccgaaac ggcggaagag
    11761 aacggatatc aagtgattat tgccggcgcg ggcggcgcgg cacacctgcc gggaatgatt
    11821 gcggcaaaaa cgctggtccc ggtactcggc gtgccggtac aaagcgctgc gctcagcggc
    11881 gtggatagcc tctactccat cgtgcagatg ccgcgcggca ttccggtggg tacgctggcg
    11941 atcggtaaag ccggggcggc gaacgccgca ctgctggcag cgcaaatttt ggctacgcat
    12001 gatagcgcgc tgcatcggcg catcgccgac tggcgcaaag cacaaaccga tgaggttctg
    12061 gaaaatcccg atccgcgggg gacgctatga agcaagtttg cgttctcggc aacgggcaac
    12121 tgggccgaat gctgcgccag gcgggcgaac cgctgggtat cgccgtctgg ccggttggtc
    12181 tggatgcaga gcctaccgcc gtgccggtac agcagagcgt cattaccgca gagattgagc
    12241 gctggccgga aaccgcgctt acccgcgagc tggcgcgcca cccggccttc gtcaatcgcg
    12301 atgtatttcc gatcatcgcc gaccgtctga cacaaaaaca gcttttcgat aaactgggac
    12361 tcgcgaccgc gccgtggcag ctgctgtcca gcgccgacga gtggtccggc atctttgacc
    12421 gtctgggcga actggcgatt attaagcgtc gcgttggcgg ctacgacggt cgcgggcagt
    12481 ggcgtctacg cgcggacgaa accgggcaac tgccggatga ctgctatggc gaatgtattg
    12541 ttgagcgcgg tatccatttt tccggcgaag tgtcgttagt cggcgcgcgc gctcatgacg
    12601 gcagtaccgt gttttacccg ctaacgcaca atttgcatca ggacggcatc ttgcggacca
    12661 gcgtcgcgtt cccacaggcg aacgccgaac agcaggagca ggcggaatcg atgctgtcag
    12721 caattatgca ggcgttgaac tacgtcggcg taatggcgat ggaatgtttt atcacgccgg
    12781 aaggcctgtt aatcaatgaa ctggcgccgc gcgtgcataa cagcggacac tggacgcaaa
    12841 atggcgccag catcagtcag tttgaattgc atttgcgcgc gattaccggc ttgccgttgc
    12901 ccgcgccggt gattaacgcc ccgtcggtga tgatcaatct gatcggcagc gagctgaatt
    12961 acgactggct gaagctgccg ctggtacatc tgcactggta tgataaagcg gtacgtccgg
    13021 ggcgaaaagt cggccatctg aatctgaccg acagcgatac gtcacgtctt agcgccaccc
    13081 tggaagcgct ctctccgctc ctgccgggcg aatacgccag cggcattatc tgggcgcaaa
    13141 gtaagcttaa ataaacagcg tgggcggcgc attctctgtc gccgcccgtc gcgatcacag
    13201 acagatgcag gttcccgccc tgcccgccag ggtatcgtca atacgcgaca gcgcgccaat
    13261 ccatgccggc tttccgcacc gcttcacata cccgcttacc gcggtcacct tcggtcccat
    13321 cgcgccatcg gctttggcaa acggcgccag ctcatcgggc gaagcctgac gaatagcgcg
    13381 ctgctgcggc gttccccaat gttcatacac cgcatccgca tccgtcaaaa tgatcagacc
    13441 atcggccgct atctgctccg ccagcaatgc cgccgccagg tctttatcta tcaccgcctc
    13501 gaccccttcg ccctcgccag caacaggtac cccgccaccg ccgctgcaaa tcaccacatg
    13561 gccctctttt agcaataact caatagcggt gctttcgata atctgacgcg gcgccgggga
    13621 agcgacgaca cggcgcagat attttccatc acgtttcata tgccagccat aagtcgcttc
    13681 cagcgccatt tgctcttctg gcgaataaac gggaccgata aacttttccg gttcaagaaa
    13741 agcaggatcg tccgccgata cctttattcg cgttaatacc gcagtcaccg gcggcatatc
    13801 gggttcaagc gccagacgct gcgccagcat atagccgatc attccctgac tttccgccac
    13861 cagcacatcc agcggataag gctcaacggc tttccaggca aggttctgta aagccaacag
    13921 gccgacctgg gggccgttgc catgtactat cgccagccga tacgagcggg caagtcgtgc
    13981 cagcgcaggc accgcgtcgg caatattgcg atattgattc tctgccgtta gcgcttctcc
    14041 gcgctgcaat aatgcgttgc cgccaagagc aactaccaac gttttcattc cctatccttt
    14101 tactatttgt tgtccaagcc agaaccccag cagcgtatcc gcgccagagg tgtgccccag
    14161 cgccagcagt ccgtcaatcg ccgtttctgt gcgagcatct cgtcgcagcg catgaataaa
    14221 gtggagtaaa ggcgacgcga aataccccat agccgcatag cgtaaatagc tgacgctcac
    14281 gagcgtcgtc gcccgatcaa ggctgccgga ttgggcaaaa aaattacgcc cggcgcgttc
    14341 atctatggcg ccaaaatacc aggccgccag caacattccc gtcagcgtgt cctcatgact
    14401 gggcgttaag cccggccctt tacccagcca tagccgccag tcagtcgcag cacctgcaag
    14461 cgctgactga aagcagtgac aaaactggcg aagttccgga catagaggct gagctgcggc
    14521 gacggttaac ggcccaaaca gtcccgtctc ctcactacgc tgcatgtacg tcgcgttaag
    14581 gcgcggcgac gcaagatagc gtggaacccg cagcgaacag cgcctctccg gctcgcataa
    14641 aagaaactcg ccaatctgaa taccggcagc ggttaactgc ggtttttcgc catcggtgag
    14701 cacatcacgc aaggcgtcaa aatcgccgcc gcgcagtatc caccctcctg gactgaagcc
    14761 gctcccccga cggtgaagcg ttaataactc accgcttttc gccacaaaat taatagagcg
    14821 acgccatacc cctgacatct gccagggttg ccgataatcc gccgattgtc ggcttgccat
    14881 aagaggatgg atacgtttca tgagacgctc tcttaactta cgcccatgct ttccgccagc
    14941 gcttccagcg cctgctcgaa acaggccagc ggcgcacgga cggttcccgc gccaatctga
    15001 ccaattcccg cctctttatg cgcgataccc gtgttaatca gcggcgtaat tccggtctcg
    15061 accacgcggc ggatatccag tcccagacag gccccctgaa aatcccagcc ggggatttgt
    15121 agctgcatgt tgcgttcgag ataaatttca gccatctctt cagaaacaga tttcgccgct
    15181 tccattcccc cggcaccgac aaaacgcgtt acgccaggcg cggcaatcat cgctgcgccg
    15241 ccaataccaa acgtttcagt aatggcgctg tcgcccatgt ccgggttggc ctgatcctgc
    15301 gaaaaaccgg taaaaaatag cccctgcggc gtattaacag gcgcggtgaa ccaacggtcg
    15361 cccagaccgc taacccgaat gccaaacata tcgccattgc gggtcatcgc cgtcacaata
    15421 ctgccggcgc gaatctgcgc gcccgcgtcc atggcggctt tacagtaggc catcgccaga
    15481 ttaaggaaga attgatcggt gacgctcaga aaatccatca cttccgctat ctgctgctta
    15541 tcgtgttgca gacgggcgat atgcggcgcc aacgtgcgca tcagcaatgc ggaagaggcg
    15601 atattgcgct ggtggaattc atctcccatc gtaatgccct gcgccatcat cgcggtcagg
    15661 tcaagccccc gctccagacg acccagcgcc gcgcttaata ccggcatcag cacatcgcgc
    15721 atccagcgca aacgttgctg aacatcttcg ccataggcgc cgaaacgcat cactttgccg
    15781 atcccttcgt tgagattgca gtacgcgcga ttgccgtcgg tgatattttc cacgaccagc
    15841 atcggcatac tggctgacgt aataccgccc atcggcccca cggcgttaac gtgatggcag
    15901 ggaataaagt tgacctttcc ctgctctaac agcgcgagcg cgctcatttc atctttggcc
    15961 catccttcaa acaggcatgc gccgatacag gcccctttca tcgggccggt catctcttgc
    16021 cagcgcatcg gcggcccggc atgaagaagc gttttcccct gattgagtac gctaattaat
    16081 gaagaagctg gcttcacatc cagccagtgc ggacgtgcgc gacgaatttg ttcgatgact
    16141 gcagcgttgg cttgcgccac tgatgtaaat atgggaaccc cttattgcaa acgttctaac
    16201 agacgagcca gttttttatt accgccagcg acaggcgccc actggtagtg caccacgggc
    16261 ataccggcag cctgtaaatc cagcgcgaag ctacgtaacc cggcattaat caccgctact
    16321 gcttccagta accggggagc tgatggatga gtagaagaga gagtgggtcg aatcagttcc
    16381 gcggccaaca gagtggcttc gggaagagaa tccactaccg tgatgccggc atcttcgagc
    16441 gcggcgattt gttgcgagcg gcactgagga tcgcgttccg ttccggtgac ggttgcgatg
    16501 gcgaacagcg gctggtcgct ggcgcgtgcg gcgcatgcct tctgccaggc ctgaatcagc
    16561 gatgcggcgg gatcggcggt cgcgccaaaa ccaataacga cgtccactaa taacacgcgt
    16621 acctgcggtt gtgcgccaag cccggcgata agctgattac gtaacgccgg gtcaatcatc
    16681 ggatgtggtc gcccaacggt ataaaagtca tcgcccagat cgataatctg gtggccgtca
    16741 gcgtcaagca tcatgccatg gtgatgttcc gtatccgtcg cgacgcccag atagccggcc
    16801 agcagtcccg ccgcttccgc cgccagcgtt ccgccggtat agagaccacg aatcacgccg
    16861 cctgttgaaa ccatttcttt acgctgcgac gtcacgcgag acaataaaca tgccagtcgg
    16921 gcagcttcat ccagcgtcga ggcaaaccag acgttttcct cacgcgcaac gggagaggaa
    16981 aaccctaaga acagcgctac aacgggtttc ccggtggctt tcatcgccgc gataatatgc
    17041 tgacgaaccg catcagcagg cggtttggag acaaaggcca gcacctggct cttttcatcc
    17101 gcgctgagta tgtccagtgc cgttagcgcg ctgatcccgc cgacctcggc gctcaaatcg
    17161 cgtccgccaa gcccgatggc atgggtaatc ccttcccccg ccagcgcaat ctgtgaacag
    17221 agctcctgaa taccggtgcc ggaagcgcca atcaccccga tgttgccctc tggcatgacg
    17281 ttagcgaaag ccagcggcgt attggcgatc atagcggtgc cgcaatctgg ccccatgacc
    17341 agcagtccct tatcacgcgc ccggcgtttt agtctgattt cgtcgtccag cgtgacatta
    17401 tcggagaaga tcatcacgtt caacgaacga gccagcgcct gctccgccag ttccgccgca
    17461 tattcgccgg ccaccgatac cagcgccaga ttcgcctctg gcagtttctg acaggcgctt
    17521 tcccagcgtc tgacctggat taacgactgg ctgccgctgc ttccctgcgc caactgctgc
    17581 aatgcttctt cgagctgtcg cacaatcacc tgcgtaatgc cgtcatctac cgcttcggta
    17641 cgaatcgcca cgcaaatgtc attgggcgta gcgccatgaa aatcgtcatg ccagaaaccg
    17701 gtagtttcca gcagcgactt attcgcaggc gtacccatca ttaccgatac atcatcaaca
    17761 ttttcggact cactcagctt tcgagaaata atcattaagc tgacagagtc ctgaaaacac
    17821 ccttttttaa taaaggcgtg gatcataaca actccttaat aattgcaccc attgcaattg
    17881 cacgagcagt gttaatgtgc gcttcacggt atatatccgg gagg
//
LOCUS       DAJVBX010000083        17776 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.083, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000083 DAJVBX010000000
VERSION     DAJVBX010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 17776)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17776)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17776
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.083"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(191..832)
                     /gene="lipB"
                     /locus_tag="OPV72_002412"
     CDS             complement(191..832)
                     /gene="lipB"
                     /locus_tag="OPV72_002412"
                     /EC_number="2.3.1.181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000284017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoyl(octanoyl) transferase LipB"
                     /protein_id="HCR9914687.1"
                     /translation="MYQDKILVRQLGLQPYEAISQAMHNFTDMRDENSHDEIWLVEHY
                     PVFTQGQAGKAEHILMPGDIPVVQSDRGGQVTYHGPGQQVMYVLLNLKRRKLGVRDLV
                     TLLEQTVVNTLAEMGIEAHPRADAPGVYVGEKKICSLGLRIRRGCSFHGLALNVNMDL
                     SPFLRINPCGYAGMEMAKITQWKEDATTDNIAPRLLANILALLNNPPYEYIAT"
     gene            complement(932..1195)
                     /locus_tag="OPV72_002413"
     CDS             complement(932..1195)
                     /locus_tag="OPV72_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbeD family protein"
                     /protein_id="HCR9914688.1"
                     /translation="MKTKLNELLEFPTPFTYKVMGQALPELVDQVVEVVQRHAPGDYS
                     PTVKPSSKGNYHSVSITINATHIEQVETLYEELGNIDIVRMVL"
     gene            complement(1303..2514)
                     /gene="dacA"
                     /locus_tag="OPV72_002414"
     CDS             complement(1303..2514)
                     /gene="dacA"
                     /locus_tag="OPV72_002414"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase DacA"
                     /protein_id="HCR9914689.1"
                     /translation="MKTTFSARFMQRMALTTALCATFISTAHADDLNIKTMIPGVPQI
                     DAESYILIDYNSGKVLAEQNADERRDPASLTKMMTSYVIGQAMKAGKFKETDLVTVGN
                     DAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAFVG
                     LMNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDVPNEYAVYKEKEFT
                     FNGIRQLNRNGLLWDNSLNVDGIKTGHTSKAGYNLVASATEGQMRLISAVMGGRTYKG
                     RETESKKLLTWGFRFFETVNPLKAGKEFASEPAWFGNTDRASLGVDKDVYLTIPRGRM
                     KDLKASYVLNTAELHAPLQKNQVVGTINFQLDGKTIEQRPLVVLQEIPEGNFFGKIID
                     YIKLMFHHWFG"
     gene            complement(2653..3786)
                     /gene="rlpA"
                     /locus_tag="OPV72_002415"
     CDS             complement(2653..3786)
                     /gene="rlpA"
                     /locus_tag="OPV72_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic peptidoglycan transglycosylase RlpA"
                     /protein_id="HCR9914690.1"
                     /translation="MHKQLPVICVAAGIVLLAACTNDGGQQQTTVAPQPAVCNGPTVE
                     ISGAEPRYEPLNPTANQDYQRDGKSYKIVQDPSRFSQAGLAAIYDAEPGSNLTASGEM
                     FDPMQLTAAHPTLPIPSYARITNLANGRMIVVRINDRGLYGTDRVISLSRAAADRLNT
                     SNNTKVRIDPIIVAPDGSLSGPGMACTTVAKQTYALPPRPDLSGGMGSASSAPAQPQG
                     DVLPVSNSTLKSDDTTGAPVSSSGFLGAPTTLAPGVLEGNEPTPAPQTAPVSAPVTAP
                     ATATPVSAPAAAAPVSAPVSAPAAAASGRFVVQVGAVSDQTRAQQYQQRLSQQFSVPG
                     RVIQNGAVWRIQLGPFASKAEASALQQRLQTEAQLQSFIASAQ"
     gene            complement(3797..4909)
                     /gene="mrdB"
                     /locus_tag="OPV72_002416"
                     /gene_synonym="rodA"
     CDS             complement(3797..4909)
                     /gene="mrdB"
                     /locus_tag="OPV72_002416"
                     /gene_synonym="rodA"
                     /EC_number="2.4.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004885876.1"
                     /note="rod shape-determining protein RodA; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase MrdB"
                     /protein_id="HCR9914691.1"
                     /translation="MTDNPNKKTFWDKIHIDPTMLLILLALLVYSALVIWSASGQDIG
                     MMERKIGQIAMGLVVMVVMAQIPPRVYEGWAPYLYIICIILLVAVDAFGAISKGAQRW
                     LDLGIVRFQPSEIAKIAVPLMVARFINRDVCPPSLKNTAIALVLIFMPTLLVAAQPDL
                     GTSILVALSGLFVLFLSGLSWRLIGVAIVLIAAFIPILWFFLMHDYQRQRVMMLLDPE
                     TDPLGAGYHIIQSKIAIGSGGLRGKGWLHGTQSQLEFLPERHTDFIFAVLAEELGLVG
                     ILILLALYILLIMRGLWIAARAQTTFGRVMAGGLMLILFVYVFVNIGMVSGILPVVGV
                     PLPLVSYGGSALIVLMAGFGIVMSIHTHRKMLSKSV"
     gene            complement(4912..6813)
                     /gene="mrdA"
                     /locus_tag="OPV72_002417"
     CDS             complement(4912..6813)
                     /gene="mrdA"
                     /locus_tag="OPV72_002417"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-transpeptidase MrdA"
                     /protein_id="HCR9914692.1"
                     /translation="MKRQNSFRDYTAESALFVRRALVAFLGILLLTGVLIANLYNLQI
                     LRFTDYQTRSNENRIKLVPIAPSRGIIYDRNGIPLALNRTIYQIEMMPEKVDNVQQTL
                     DALRSVVDLNDDDIAAFKKERARSHRFTSIPVKTNLTEVQVARFAVNQYRFPGVEVKG
                     YKRRYYPYGSALTHVIGYVSKINDKDVERLDRENKLANYAATHDIGKLGIERYYEDIL
                     HGQTGYEEVEVNNRGRVIRQLKEVPPQAGHDIYLTLDLKLQQYIETLLAGSRAAVIVT
                     DPRTGGVLSLVSMPSYDPNLFVDGISSKDYSGLLNDPNTPLVNRATQGVYPPASTVKP
                     YVAVSALSAGVITRNTSLFDPGWWQLPGSEKRYRDWKKWGHGHLNITKSLEESADTFF
                     YQVAYDMGIDRLSEWMGKFSYGHYTGIDLAEERSGNMPTREWKQKRFKKPWYQGDTIP
                     VGIGQGYWTATPIQMSKALMILINDGVVKVPHLLMSTAENGKQVPWVQPHEPPVGDIH
                     SGYWEIAKDGMYGVANRPNGTAHKYFASAPYKIAAKSGTAQVFGLKANETYNAHKIAE
                     RLRDHKLMTAFAPYNNPQVAVAIILENGGAGPAVGTIMRQILDHIMLGDNNTHLPAEN
                     PVVAAAEDQ"
     gene            complement(6844..7311)
                     /gene="rlmH"
                     /locus_tag="OPV72_002418"
     CDS             complement(6844..7311)
                     /gene="rlmH"
                     /locus_tag="OPV72_002418"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016245807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HCR9914693.1"
                     /translation="MKLQLVAVGTKMPDWVQTGFTEYLRRFPKDMPFELIEIPAGKRG
                     KNADIKRILDKEGEQMLAAAGKNRIVTLDIPGKPWDTPQLANELERWKQDGRDVSLLI
                     GGPEGLSPACKAAAEQSWSLSALTLPHPLVRVLVAESLYRAWSITTNHPYHRE"
     gene            complement(7315..7632)
                     /gene="rsfS"
                     /locus_tag="OPV72_002419"
                     /gene_synonym="rsfA"
     CDS             complement(7315..7632)
                     /gene="rsfS"
                     /locus_tag="OPV72_002419"
                     /gene_synonym="rsfA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007373852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HCR9914694.1"
                     /translation="MQGKALQDFVIDKIDDLKGQDIIALDVQGKSSITDCMIICTGTS
                     SRHVMSIADHVVQSSRAAGMLPLGVEGENAADWIVVDLGDVIVHVMQEESRRLYELEK
                     LWS"
     gene            complement(7961..8569)
                     /locus_tag="OPV72_002420"
     CDS             complement(7961..8569)
                     /locus_tag="OPV72_002420"
                     /EC_number="3.1.3.73"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobalamin/alpha-ribazole phosphatase"
                     /protein_id="HCR9914695.1"
                     /translation="MRLWLVRHGETEANVAGLYSGHAPTPLTEKGIGQAKTLHTLLRH
                     APFDRVLCSELERARHTARLVLEGRDTPQHILPELNEMYFGDWEMRHHRDLTHEDAES
                     YAAWCTDWQNAVPTNGEGFQAFTRRVERFISRLGAFSDCQNLLIVSHQGVLSLLIARL
                     LAMPAASLWHFRVEQGCWSTIDICEGFATLKVLNSRAVWRPE"
     gene            8666..9760
                     /locus_tag="OPV72_002421"
     CDS             8666..9760
                     /locus_tag="OPV72_002421"
                     /EC_number="4.1.1.81"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine-phosphate decarboxylase"
                     /protein_id="HCR9914696.1"
                     /translation="MALFNSAHGGNIREAATVLGISPDQLLDFSANINPLGMPVSVKR
                     ALIDNLDCIERYPDADYFHLHQALARHHQVPASWILAGNGETESIFTVASGLKPRRAI
                     IVTPGFAEYGRALAQIGCEIRRWSLREADGWQLTDAILEALTPDLDCLFLCTPNNPTG
                     LLPERQLLQAIADRCKSLNINLILDEAFIDFIPHETGFIPALKDNPHIWVLRSLTKFY
                     AIPGLRLGYLVNSDDAAVARMRRQQMPWSVNALAALAGEVALQDSAWQQATWHWLREE
                     GARFYQALCQLPLLTVYPGRANYLLLRCEREDIDLQRRLLTQRILIRSCANYPGLDSR
                     YYRVAIRSAAQNERLLAALRNVLTGITPAD"
     gene            complement(9735..10376)
                     /gene="nadD"
                     /locus_tag="OPV72_002422"
     CDS             complement(9735..10376)
                     /gene="nadD"
                     /locus_tag="OPV72_002422"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HCR9914697.1"
                     /translation="MKSLQALFGGTFDPVHYGHLKPVETLANLIGLSRVIIMPNNVPP
                     HRPQPEASSAQRKYMLELAIADKPLFTLGERELQRNAPSYTAQTLKAWREEQGPEAPL
                     AFIIGQDSLLNFPTWHDYDTILDNTHLIVCRRPGYPLEMTQAQHQQWLEQHLTHTPDD
                     LHQLPAGKIYLAETPWLNISATLIRERLEKGESCDDLLPENVLNYINQQGLYR"
     gene            complement(10378..11409)
                     /gene="holA"
                     /locus_tag="OPV72_002423"
     CDS             complement(10378..11409)
                     /gene="holA"
                     /locus_tag="OPV72_002423"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HCR9914698.1"
                     /translation="MIRLYPEQLRAQLNEGLRAAYLLLGNDPLLLQESQDAIRLAAAS
                     QGFEEHHAFTLDPSTDWGSLFSLCQAMSLFASRQTLVLQLPENGPNAAMNEQLATLSE
                     LLHDDLLLIVRGNKLTKAQENAAWYTALADRSVQVSCQTPEQAQLPRWVAARAKAQNL
                     QLDDAANQLLCYCYEGNLLALAQALERLSLLWPDGKLTLPRVEQAVNDAAHFTPFHWV
                     DALLMGKSKRALHILQQLRLEGSEPVILLRTLQRELLLLVNLKRQSAHTPLRALFDKH
                     RVWQNRRPMIGDALQRLHPAQLRQAVQLLTRTEITLKQDYGQSVWADLEGLSLLLCHK
                     ALADVFIDG"
     gene            complement(11409..11999)
                     /gene="lptE"
                     /locus_tag="OPV72_002424"
     CDS             complement(11409..11999)
                     /gene="lptE"
                     /locus_tag="OPV72_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS assembly lipoprotein LptE"
                     /protein_id="HCR9914699.1"
                     /translation="MRYLVTLLLSLAVLVTAGCGWHLRSTTQVPASMKTMILDSGDPN
                     GPLSRAVRNQLRLNNVNLLDKDTTRKDVPSLRLGTVTISQDTASVFQDGQTAEYQMVM
                     TVNASVLIPGHDIYPISTKVYRSFFDNPQMALAKDNEQAMIVQEMYDKAAEQLIRKLA
                     SVRAADIQATKEEATADNETAAPASTPARVSTTLSN"
     gene            complement(12014..14596)
                     /gene="leuS"
                     /locus_tag="OPV72_002425"
     CDS             complement(12014..14596)
                     /gene="leuS"
                     /locus_tag="OPV72_002425"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008456064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HCR9914700.1"
                     /translation="MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYP
                     SGRLHMGHVRNYTIGDVVARYQHMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTY
                     DNIAYMKNQLKTLGFGYDWSREIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCP
                     NDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKT
                     MQRNWIGRSEGVEITFDVKGYDNTLTVYTTRPDTFMGATYLAVAAGHPLAQKAAANNA
                     ELAAFIDECRNTKVAEAEMATMEKKGVDTGYKAIHPLTGEEIPVWAANFVLMEYGTGA
                     VMAVPGHDQRDYEFASKYGLTIKPVILAADGSEPDLSEQALTEKGVLFNSGEFDGLAF
                     EAAFNAIADKLAEKGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQL
                     PVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPQY
                     QEGMLDSKAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVTSDEPAKQLLCQ
                     GMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSK
                     NNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFIKRVWKLVYEHTA
                     KGPVAALNVDALSEDQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAP
                     QEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQELGGEGDIDNAPWPVADEQAMVEN
                     TTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLN
                     LVVG"
     gene            14833..15174
                     /locus_tag="OPV72_002426"
     CDS             14833..15174
                     /locus_tag="OPV72_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_447100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HCR9914701.1"
                     /translation="MARLLIREDRTKAKELIVKKNAVVIHPQDCVATAITALKAGETA
                     TMFIGEREISVVLHQDVPFGHKFAICDVPFHGEVYKYGESIGRATQEIKSGDYVHVHN
                     VESERGRGDWK"
     gene            15191..16363
                     /locus_tag="OPV72_002427"
     CDS             15191..16363
                     /locus_tag="OPV72_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_447101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HCR9914702.1"
                     /translation="MIMSNETFLGFRRPDGRFGIRNYVLILPTSVCANKVAQDIARQV
                     KGATWVNNDFGCCQVAGDARLTEKTLINVANNPNVGAIVVVGLGCEGAEPLRIAEEIT
                     AFGKPTSCITIQEEGGTLKCQARGISLARDYAQQLSMQKPQQAPVSELLLAMECGGSD
                     TTSGLASNPSCGVASDKLIRCGGSSILSETTEFIGAEHVMAKRAVTPEVGQQLIDLVV
                     GCEARAKALGEDIRGGQPTPGSIKGGLTTIEEKSLGCMHKAGHAPLQGVLEYADSPTH
                     PGLWIMDTPGQDIESISGMVAGGAQIVIFTTGRGTPAGNPIAPVIKITGNKATWEMMQ
                     DNIDIDVSAIMSGEASITQMGEEIYQEILRVANGKTTKSEDLGHNEFSIYKIAPTF"
     gene            16413..17366
                     /locus_tag="OPV72_002428"
     CDS             16413..17366
                     /locus_tag="OPV72_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease 2"
                     /protein_id="HCR9914703.1"
                     /translation="MKIKKTLERFPGGMMVVPLIIGALFKTFAPEALEIGGFVISISH
                     GAMAILGMFLVCMGADIQFKAAPKALKKGAAITFAKFASGVIIGILVGKFCGPDGLLG
                     LSALAIISAMTNSNSGLYAALVGEYGDETDGGAIAVISLNDGPFFTMLALGSAGMVSI
                     PFMNLVAVIIPIIIGMILGNLDEDMRKFLKQGSVVTIPFFAFGLGYSIDFARLITAGS
                     SGILLGLMTVAIGGFFNIFADRVTGGSGVAGAAVSTTSGNAVATPAAIALLDPHFTDL
                     ASTAAAQVAASTIITALCAPFLTVWIKKRYDRKLNPAAAGG"
     gene            17434..>17776
                     /locus_tag="OPV72_002429"
     CDS             17434..>17776
                     /locus_tag="OPV72_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrpR N-terminal domain-containing protein"
                     /protein_id="HCR9914704.1"
                     /translation="MNKTKDIAASPLCFVSPYPQLAKAAEALVAQLDYAVTIHQTTLN
                     RILDELPLLESRGHQVLISRGGCAEILKKHSKLPVVEIKMSGYDILDALIPFKGQKGT
                     VGIVGFSSVIKG"
BASE COUNT         4012 a         4690 c         4883 g         4191 t
ORIGIN      
        1 aagataagta acagcaaggc cgggattttg ttcacggaaa attcctcatc atgaggactg
       61 aagaggccat gccgcctggc ggctacagca gggatataac gaaaatatag aaagcggggg
      121 gagaagtaaa gcattcaaat catatatgat taatgaccca taaatttctt gggccattat
      181 attttacgca ttaagtagca atatattcat acggtggatt atttagcaga gctaaaatat
      241 tcgccagcaa gcggggcgca atattatctg tggtagcgtc ttccttccac tgcgttattt
      301 tagccatttc catgccggca taaccacacg ggttgatgcg taggaaagga gaaagatcca
      361 tgttaacgtt tagcgctaaa ccgtggaatg agcagccgcg acggatacgt aaacccagcg
      421 agcagatttt cttttcaccc acgtagacgc ccggcgcatc ggcgcgcgga tgcgcctcaa
      481 tacccatttc agccagcgta ttcaccacgg tctgttcaag tagggtgact aaatcacgca
      541 cgcccagttt acgtcgtttc aggttaagta aaacgtacat tacctgttgg cccggaccat
      601 gataggtcac ctgtcctcca cgatcgctct gcacaacggg aatatcgcca ggcatcaata
      661 tatgttccgc tttaccggcc tggccctggg taaacaccgg gtaatgctca accaaccaga
      721 tttcatcatg gctgttttca tcgcgcatat cggtaaagtt atgcatggcc tgagagatag
      781 cttcataggg ctgaaggccg agctggcgga caaggatttt atcctgatac aaaacggcat
      841 ctccgtagag aatgaaaaaa gagaggaaag tatatcacag cgggggaggc ggggagttac
      901 ccggataaga ccgggtaacc gtctggatgt attacaatac cattcgcacg atatcaatat
      961 tacccagttc ttcgtacaac gtttcaacct gttcaatatg ggtggcatta atggtgatag
     1021 agaccgagtg gtagttgcct ttgctgctcg gttttaccgt cggagagtaa tcaccaggcg
     1081 catggcgctg taccacttca accacctgat caaccagctc aggtaacgcc tgccccatta
     1141 ctttgtaagt aaatggcgta gggaattcaa gcagttcgtt aagtttggtt ttcatgtcag
     1201 ctccggcatt acgtaaaaaa ataacaactc ccgccacagg gcgggagttt tactgatgca
     1261 tagtatatgg ggacgaaaat cacactttca agcgttcaat ttttatccaa accagtgatg
     1321 gaacattaat ttaatgtaat caatgatttt accgaagaag ttcccttccg ggatctcttg
     1381 cagtacgacc agcggacgct gctcgatggt tttaccgtcc agctggaagt tgatggtgcc
     1441 gaccacctgg tttttctgca gcggcgcgtg cagttctgcg gtattcagta catagctcgc
     1501 tttcaaatct ttcatgcgac cgcgagggat cgtcaggtaa acgtctttat cgacgcccag
     1561 cgaggcgcga tcggtattac caaaccaggc gggttcagag gcgaactctt taccagcctt
     1621 cagcggatta acggtttcaa agaaacggaa gccccacgtc agcagttttt tgctttctgt
     1681 ttcacggcct ttataggtcc gtccgcccat tacggcggaa atcaatcgca tctggccttc
     1741 ggttgcggaa gcgaccagat tatagcccgc tttgctggta tggccggttt tgatgccgtc
     1801 cacattcagg ctgttatccc acagcagacc gttacggttt aactggcgaa tgccgttaaa
     1861 ggtgaactct ttttctttat aaacggcata ttcgttcggc acatctcgaa ttaacgcctg
     1921 gccaatcagc gccatatcgc gagctgaact gtattgtccg tcggcgtcca ggccgtgtac
     1981 ggtctggaag tgggtatttt tcagccccaa cgcgttcaca tagctgttca tcagcccgac
     2041 gaaagcatcc tggctaccgg cggcgaaatc agccatcgcc acacaggcgt cattgccgga
     2101 ttgcagattg atgccgcgta tcaactgaga gaccggtacc tgcattcccg gtttgaggaa
     2161 catcagcgaa gagcctttaa ataccggatt gccggtggcc caggcgtcat taccgacggt
     2221 aaccaggtcg gtttctttaa atttacccgc tttcattgcc tgtccgatga cgtaactggt
     2281 catcatcttc gtcagactag ccgggtcgcg acgttcgtcg gcgttttgtt ccgccagaac
     2341 tttgccggag ttgtagtcga tcaggatgta ggattccgca tcgatctgcg gaacacccgg
     2401 gatcatagtt ttgatattca ggtcatcggc atgtgcggtt gagataaacg tggcacaaag
     2461 cgccgtggtg agcgccatgc gctgcataaa acgagcggaa aaagtggtct tcatggtctg
     2521 aactacgacg tccgtgatga aattaaaaaa gagccctact atagcaaaag cataactggc
     2581 aggcatctga ctttccgcgt gactttgtta atgtcattta cagaaattga cagtacagat
     2641 acctgcaatc ggttactgcg cgctggcgat aaaggactgt aattgtgctt ctgtttgcaa
     2701 acgttgctgt aacgcgctgg cttcggcttt actggcaaaa ggccccagtt gaatacgcca
     2761 gaccgcgccg ttttgtatta cgcgtcctgg tacgctgaac tgctggctta aacgctgttg
     2821 gtactgctgc gcacgcgttt gatcgctgac ggcgccgact tggacgacga aacgaccgct
     2881 cgccgcggcg gcaggcgcgc tcaccggggc agataccggg gctgcggcgg caggcgcgct
     2941 caccggcgtc gcagtcgctg gagccgtcac cggcgcggaa accggcgctg tctgtggcgc
     3001 cggcgtcggt tcattaccct ccagcacgcc aggcgccagc gtggtcggcg cgccgaggaa
     3061 gccgctgctg ctcaccggcg caccggtggt atcgtcactt ttcaacgtgg aattactgac
     3121 cggaagaacg tcgccttgcg gttgcgcagg cgctgaagag gcgcttccca tgccgccgct
     3181 taaatcaggg cgcgggggca gagcgtaggt ctgtttcgcc accgtcgtac aggccatccc
     3241 cgggccggag agcgaaccat ccggcgccac gataatgggg tcaatccgta ctttagtatt
     3301 attcgaggta ttcagacgat ccgccgctgc gcgggacagg gagatgaccc gatcggtgcc
     3361 atagaggccg cgatcgttaa tacgcacgac gatcatgcga ccgttggcca ggttggtgat
     3421 tcgcgcatag ctggggatag gcagtgtcgg atgggcggcg gtaagctgca tcggatcgaa
     3481 catctccccg gaggcggtta aattactgcc gggttccgca tcataaatag cggccaggcc
     3541 agcctggcta aagcgggacg ggtcctgaac gattttataa cttttaccgt cacgctgata
     3601 atcctggttt gcggtcggat tcagaggttc ataacgcggt tccgctccgc tgatttccac
     3661 agtcggacca ttacataccg caggttgcgg cgcgacggtg gtttgctgct gaccgccgtc
     3721 attagtacat gccgcgagta gtactatccc tgccgcgacg cagattacag gcaactgctt
     3781 atgcattgcg caccccttat acgcttttcg acaacatttt tctgtgggtg tggatcgaca
     3841 tcacaatccc gaacccggcc atcagcacaa tcagtgcgga gcccccgtag ctgaccaagg
     3901 gtaaaggtac tccaaccaca ggcagaatac cgctcaccat accaatattt acgaagacat
     3961 aaacgaataa tattaacatt aatccgccag ccatcacgcg accaaatgta gtttgcgctc
     4021 tggcggcaat ccacagaccg cgcattatta gcaaaatata gagcgcgagc agaatcagga
     4081 tgcccaccag accgagctct tccgccagta ccgcgaaaat aaagtcggta tggcgttcgg
     4141 gtaaaaactc cagctgcgac tgggtgccgt ggagccagcc tttaccgcgc aggccgcctg
     4201 agccaatggc gattttagac tgaataatat gatagcccgc gcccagcgga tcggtctccg
     4261 gatcaaggag catcatgacg cgctggcgtt ggtaatcgtg catcaggaaa aaccacaaaa
     4321 taggaataaa tgcagcgatc aatacaatgg cgaccccaat taagcgccag ctcaggccag
     4381 acaaaaatag gacaaagaga ccggaaaggg cgaccagaat agacgtcccc aggtccggct
     4441 gggcggcgac cagcagggta ggcataaaga ttaataccag ggcgatggcg gtatttttca
     4501 gcgagggcgg gcagacgtcg cggttaataa agcgggcgac catcagcggc acggcgattt
     4561 tggctatttc cgaaggctga aagcgaacga ttcccagatc gagccagcgc tgcgcgccct
     4621 tggatattgc gccgaaggca tcaacggcga ccagcagaat gatacaaatg atatagagat
     4681 agggcgccca gccttcatac acgcgcggcg ggatctgcgc catcaccacc ataaccacca
     4741 gccccatcgc aatctgaccg attttacgct ccatcatgcc gatgtcctgg ccgctggcgc
     4801 tccagatgac caacgcgcta taaaccagta acgccagcag aatgagtagc atcgtgggat
     4861 cgatatgaat tttatcccag aaggtttttt tgttcggatt atccgtcatg attattggtc
     4921 ctccgccgct gcaaccaccg ggttttccgc aggcaaatgg gtgttgttgt cgcccagcat
     4981 gatgtgatca aggatttggc gcatgatcgt gcctactgcc gggcctgcgc cgccgttttc
     5041 aaggatgatc gcgacggcga cctggggatt gttatacggc gcaaaggcgg tcattaattt
     5101 atggtcgcgc aggcgctcgg cgattttatg cgcattgtac gtttcgttgg ccttcaggcc
     5161 aaagacctgc gcggtgcccg acttcgccgc gattttatag ggcgcgctgg caaaatattt
     5221 atgcgccgtg ccgttagggc ggttggcgac gccatacatg ccatctttcg caatttccca
     5281 gtagccggag tgaatatcgc ccaccggtgg ctcatgcggc tgtacccacg gcacctgttt
     5341 accgttttcc gcggtgctca ttaacagatg cgggacttta actacaccgt cgttaataag
     5401 gatcatcagc gccttactca tctgaatcgg cgttgccgtc cagtagccct ggccgatgcc
     5461 caccggaatc gtatcgccct gataccacgg ttttttaaag cgtttctgtt tccactcgcg
     5521 ggtcggcata ttaccagagc gctcttctgc gagatcaatt ccggtatagt gaccatagct
     5581 gaacttaccc atccattctg acaggcgatc gatccccatg tcataggcca cctgatagaa
     5641 gaaggtatct gccgactctt caagggattt ggtgatattc agatgcccgt ggccccattt
     5701 tttccagtcg cggtagcgtt tctcagaccc cggcaactgc caccagccag ggtcgaaaag
     5761 actggtgtta cgggtgatga cgccagcgct taacgccgat acggcgacgt aaggcttaac
     5821 ggtagaagcg ggtgggtaga caccctgagt cgcgcggttc actaatggcg tgttcgggtc
     5881 gttaagcagc ccggagtaat ctttgctgga gatgccgtcc acgaaaaggt tagggtcgta
     5941 acttggcatg gagaccagcg atagcacgcc gccggtacgc ggatcggtga caatcaccgc
     6001 cgcgcgactg cctgccagca gcgtttcaat atactgctgg agcttgagat ccagcgtcag
     6061 gtagatatcg tgtccggcct gcggcggcac ctctttaagc tggcgaataa cgcggccgcg
     6121 gttgttgact tcaacctctt cataaccggt ttgcccatgc agaatatctt catagtagcg
     6181 ctcaatgccc agcttgccga tgtcatgggt ggcggcgtag ttcgccagtt tgttttctct
     6241 gtcgagacgc tcgacgtctt tatcattgat tttcgatacg tagccgataa cgtgggtcag
     6301 cgccgatccg tatggataat agcggcgttt atagcctttg acttcgacgc ccggaaaacg
     6361 gtactggttg acagcaaagc gcgcgacctg aacttccgtc aggtttgttt tcaccggaat
     6421 agaagtaaag cgatgggatc gggcgcgctc ttttttaaag gcggcgatat cgtcgtcgtt
     6481 taaatcgacc acactgcgta gtgcatccag cgtttgctga acgttatcca ccttttccgg
     6541 catcatttca atctgataga tagtgcggtt cagcgcaagg ggaatgccgt tgcggtcgta
     6601 gattatcccg cggcttggcg caattggcac cagcttgata cggttttcgt tcgagcgggt
     6661 ctggtaatcg gtaaaacgga gaatttgcag attatacaaa ttggcgatca gtacgccggt
     6721 cagcagcaaa atacccaaaa aggcgaccag cgcccgacgc acaaacagtg cggactcagc
     6781 cgtatagtca cgaaaagaat tttgtcgttt catccgctgc ttaatcttct caagacttca
     6841 cgatcactca cggtgataag ggtggttggt tgtgatgctc cacgcccggt acaaactctc
     6901 cgcgaccaga acccgaacca gcgggtgagg gagcgttaac gccgagagcg accagctctg
     6961 ttccgctgcc gctttgcagg cgggagataa tccttccggg ccgccaatca gcaaactgac
     7021 gtcgcgcccg tcctgtttcc agcgctccag ctcattggct aactgcggcg tatcccacgg
     7081 cttgcctgga atatccaggg taacaatgcg attcttaccg gcggcggcca gcatctgctc
     7141 gccctctttg tcgagaatgc gtttgatatc cgcgttcttg ccgcgtttgc ccgcagggat
     7201 ttcgatcagc tcaaagggca tatctttcgg aaaacgacgc agatattccg taaatcccgt
     7261 ttgaacccag tcgggcatct tcgtgccgac agcgacaagt tgcagcttca cgcattaact
     7321 ccagagtttt tccagttcat acaggcggcg actttcttcc tgcatgacat gcacaatcac
     7381 atcgcccaga tcgacgacaa tccagtcagc cgcattttcg ccttcgacgc ccaacggcag
     7441 cataccggcc gcgcgcgacg actgcaccac gtggtcggca atagacataa cgtgacggct
     7501 ggaggtgccg gtacaaataa tcatacagtc ggtgatactg gatttaccct gaacatctaa
     7561 ggcgatgatg tcctgacctt tcaggtcatc aattttatcg ataacaaaat cctggagtgc
     7621 tttaccctgc aagttttccc cctgggtgaa taattgcgtt ataacgatag aaaaaaggcc
     7681 aacaggctgg accggtaagg cgttgcgagt taacgctaac cttccggcgg gacgccgtgt
     7741 agtatacctg aatcagcggc gataccggga cttatgtcgc cggatcggcg tttaaaacca
     7801 gattatcatc ccatcccacg tcacagaaag catcgccatt tttgtaaaac aatttctgca
     7861 aagctctgca aggtgaaaaa agcctggctg cggagaataa cagcctgtcg ggggctgtca
     7921 atgggcgaaa ccgctgcggc gagaaaaaac ggaaaattca tcactcaggc cgccagacgg
     7981 cacgactatt taatactttc agggtggcga acccttcgca tatgtcgatt gtgctccagc
     8041 atccctgttc tacccggaaa tgccatagcg aggcggcggg cattgcgagc aggcgggcaa
     8101 tcaacaggct gagtacgccc tgatggctga cgatcagcag gttctggcaa tcgctgaacg
     8161 cgccgagtcg cgagataaag cgctctacgc gccgggtaaa agcctgaaaa ccctcgccat
     8221 tggtcggaac cgcattctgc cagtccgtac accaggcggc atagctttcg gcatcttcat
     8281 gggtgaggtc gcggtgatgg cgcatttccc agtcgccgaa gtacatctca ttaagctcag
     8341 gtaagatgtg ttgcggcgta tcccggccct ccagtacgag ccgggcggta tggcgcgcgc
     8401 gctccagctc gctgcataac accctgtcaa atggcgcgtg gcgcaataaa gtatgtagcg
     8461 ttttcgcctg gccaatccct ttttccgtta acggcgtggg agcatgtccg ctatacaacc
     8521 cggcgacatt ggcctcggtt tcgccatgac gcaccagcca caatcgcatg gtattcctca
     8581 tgaggttaaa tgcgcaaaac atgataatgc ccctgattgc gcaacgtttt tttcactaaa
     8641 atagcgtttt ttggccggag gcataatggc gttattcaac agcgcgcatg gcggtaatat
     8701 tcgggaagcc gcgacggtgt tgggcatctc gcctgaccag ttactggatt ttagcgcaaa
     8761 cattaatccg ctgggtatgc ctgtcagcgt gaaacgcgcg cttatcgaca atctggactg
     8821 cattgagcgc tacccggacg ccgattattt tcatttgcac caggcgctgg cgcgtcatca
     8881 ccaggtgccg gcatcgtgga tactggcggg aaatggcgag acggagtcaa tctttaccgt
     8941 ggcgagcggt cttaaaccgc gtcgtgcaat aattgtcacg ccaggtttcg cggagtatgg
     9001 ccgggcgctg gcgcaaattg gctgtgaaat tcgtcgctgg tctctacgcg aagcggatgg
     9061 ctggcagctt accgatgcca ttcttgaggc gttgacgccc gatctggact gcctgtttct
     9121 gtgtacgccc aataatccta ccggcctgct gccggagcgg cagttattac aggccattgc
     9181 cgatcgctgc aaatcgctga acattaacct gatcctggat gaagcgttta tcgattttat
     9241 tccgcatgag acgggcttta ttcctgctct taaagataat ccgcatatct gggtgctgcg
     9301 ttcgctgacc aaattttatg ccattcccgg cctgcggttg ggatatctcg tcaatagcga
     9361 tgacgcggcg gtggcgcgga tgcgtcgcca acaaatgccg tggtcggtta acgcgctggc
     9421 ggcgctggcc ggtgaggtag cgttacagga tagtgcctgg caacaggcga cctggcattg
     9481 gttacgggag gagggcgccc ggttttatca ggcgctttgt cagcttcccc tgctgacggt
     9541 ttatcccggg cgggcaaact atctgttgtt acgctgtgag cgagaggata ttgatctgca
     9601 gcgacggttg ctgacgcagc ggattttaat ccgtagctgc gctaactacc cggggctgga
     9661 cagccgctat tatcgtgtgg cgatacgcag cgctgcgcaa aacgagcgtc tgctggcggc
     9721 gctacgcaat gtgcttaccg gtataacccc tgctgattga tgtagttcag cacgttttcc
     9781 ggcaacagat cgtcgcagga ttcgcctttt tccagccgtt cgcggatgag ggttgcggag
     9841 atattaagcc atggcgtttc cgccaggtaa attttaccgg ctggcaactg gtgcagatcg
     9901 tctggcgtat gggtcagatg ctgttccagc cactgctggt gttgcgcctg cgtcatttca
     9961 agggggtagc cgggacgacg acaaacgatc aggtgagtgt tatcaaggat ggtgtcgtaa
    10021 tcatgccagg tggggaagtt aagcagcgag tcctggccga taataaacgc cagcggcgct
    10081 tcggggccct gttcttcgcg ccatgctttc aacgtttgcg cagtgtaaga gggcgcgttt
    10141 cgctgtagct cgcgttcacc cagcgtaaaa agcggcttat cggcgatagc cagctccagc
    10201 atatatttac gctgcgcgct ggaggcttcc ggctgggggc gatgcggcgg cacattgtta
    10261 ggcataataa tcacccgcga taagccgatc agattcgcca acgtttcaac aggtttaaga
    10321 tgtccataat gcaccggatc aaaggtgccg ccgaataaag cctgtaacga tttcatatca
    10381 cccatcaata aatacgtctg ccagcgcctt atggcagagc aggagcgaca gcccttcaag
    10441 atctgcccat accgactgac cataatcctg tttgagcgta atttctgtac gcgtcagtaa
    10501 ctgcacggcc tggcgaagct gtgcaggatg gagacgctgc aacgcgtcgc cgatcatggg
    10561 gcgacggttt tgccagaccc ggtgtttatc aaacagcgcg cgtaacggcg tatgcgcgga
    10621 ctgacgtttg agatttacca gtagcagcag ctctcgctgg agggtccgca gcagaataac
    10681 cggttcgctg ccttcaaggc gtagctgttg caggatatgc agcgcgcgtt tgcttttccc
    10741 catcagtaac gcatccaccc agtggaaagg ggtaaagtgg gcggcgtcat tgacggcctg
    10801 ctccacgcga ggaagcgtta acttaccgtc aggccaaagc agcgacagcc gttccagcgc
    10861 ctgcgccagc gccaacagat tgccctcata gcaatagcac agcagttggt tcgcggcgtc
    10921 atccagttgc aaattctgtg ctttcgctct ggcggccacc cagcggggaa gctgcgcctg
    10981 ctccggcgtc tgacaactga cctgaacgct acgatctgcc agcgcggtat accaggcggc
    11041 gttttcctgc gctttggtga gcttgtttcc gcgtactatt aataacaggt cgtcatgcag
    11101 tagctcgctc agggtggcga gttgctcatt cattgccgcg ttaggcccgt tttccggcag
    11161 ttgcagcacc agcgtttggc ggctggcgaa caggctcatc gcctggcaga gtgagaaaag
    11221 cgatccccag tcggtactgg gatcgagagt aaaagcgtgg tgctcttcga agccttgcga
    11281 cgcagccgcc agacgaatag cgtcctgact ttcctgcagc agcagcggat cgttgcccaa
    11341 taatagatat gccgcacgca gcccttcgtt gagctgcgcg cggagttgtt caggatacaa
    11401 cctgatcatt agttactcag cgtagtggag acgcgtgctg gcgtagaggc gggcgccgcc
    11461 gtctcattgt cggcggtagc ctcctctttc gtcgcctgaa tatccgccgc gcggacgctg
    11521 gccagcttac gaatcagctg ttcagcggct ttgtcgtaca tctcctgaac gatcatggcc
    11581 tgctcgttat ccttcgccaa cgccatctgc gggttatcga agaacgaacg gtacactttc
    11641 gtgctgatag gatagatgtc atggcccgga atcaataccg aggcattgac ggtcatcacc
    11701 atctgatatt ccgccgtctg gccgtcctgg aacactgacg ccgtatcctg cgaaatagtc
    11761 accgttccaa gccgcagaga cggaacgtct ttgcgcgttg tgtctttatc aagcaggttt
    11821 acgttattca gccgtaactg attacgtacc gcacgactta gcggaccgtt cggatcgccg
    11881 gaatcgagga tcatcgtttt cattgaagcc ggaacctgcg tagtgctacg cagatgccag
    11941 ccgcatccgg cggtgaccag caccgccaga gataacaaca gtgttaccag atatcgcacg
    12001 cttcctcccg cgcttagcca acaaccagat tgaggagttt acccggaacg taaatcactt
    12061 tacgcacggt aacgccatca agatattttg ccaccagatg ttcctggcct gcacgttcac
    12121 gcacctgttc ttcggtggca tccaccgcaa cggtgatctt accgcgaact ttaccgttaa
    12181 cctgcacgac aaccagcgtg gtgttttcca ccattgcctg ctcgtcggca accggccacg
    12241 gcgcgttgtc gatatcgcct tcgccaccca gttcctgcca caaggtaaag cagacgtgcg
    12301 gggtgaacgg gttaagcata cgcacgacgg cctgcagcgc ttcctgaagc agtgcgcggt
    12361 cttgttcgcc ttcctgcggg gctttcgcca gtttgttcat caactccatg atcgccgcaa
    12421 tggcggtgtt gaacgtctga cggcggccga tatcatcggt cactttggca atggttttat
    12481 gcacatcgcg acgcagcgct ttttgatctt cgctcagcgc atcgacgttc agcgccgcga
    12541 caggaccttt agcggtgtgt tcgtaaacca gcttccagac gcgtttaata aagcggtttg
    12601 cgccttctac gccggactcc tgccattcca gagtcatatc cgccggagaa gcgaacatca
    12661 taaacaggcg taccgtatcc gcgccataac gttcaaccat tacctgcggg tcgataccgt
    12721 tatttttcga cttggacatt ttactcatgc cagtgtagac cagctcatga cccgctgcgt
    12781 cttttgcttt gacgatgcgg cctttttcat cgcgctcgac gatagcgtca actggcgaaa
    12841 cccagttacg ctcgccgttc tcgccgacat aatagaacgc atccgccagt accatgccct
    12901 ggcacagcaa ctgtttagcc ggctcgtcag aggtgaccat gcccgcatcg cgcatcagct
    12961 tatggaagaa gcggaagtag agcaggtgca tgatggcatg ttcaataccg ccgatgtaga
    13021 tgtcgactgg cagccagtag tttgccgctt tcgaatccag cattccttcc tgatactgcg
    13081 ggcaggtgta acgcgcgtag taccatgacg attccataaa ggtgtcgaag gtgtcggttt
    13141 cacgcagcgc cggcataccg ttaacggtgg ttttcgccca ctcaggatcg gccttgatcg
    13201 ggctggtgat gccgtccatg acgacgtctt ccggcaaaat aaccggcagt tgatcttccg
    13261 gcgtcggcag cacggtgccg tcttccaggg tgaccatcgg gatcggcgcg ccccagtaac
    13321 gctgacggga aacgccccag tcacgcagac ggtagttcac tttacgttcg ccgacgcctt
    13381 tttccgccag tttatcggca atggcgttaa acgccgcttc aaaggccaga ccgtcgaact
    13441 caccggagtt aaacagcacg cctttttcgg tcagcgcctg ttcggaaaga tccggctcgg
    13501 aaccgtcagc ggccagaatc accggcttga tggtcaaacc gtatttggag gcaaattcgt
    13561 agtcgcgctg atcgtgaccc ggaacggcca tcaccgcgcc agtgccgtac tccatcagga
    13621 caaagtttgc cgcccagacc gggatctctt cgccagttaa cggatgaatc gctttatagc
    13681 cggtgtcgac gccttttttc tccatggtcg ccatttcggc ttcggccact ttggtgttac
    13741 ggcattcgtc gatgaacgcc gccagctcgg cgttgttcgc cgccgctttt tgcgccagcg
    13801 gatgaccggc ggccactgcc aggtaggtgg cgcccataaa ggtatccgga cgggtggtat
    13861 agacggtcag cgtgttatcg taacccttca catcgaaggt gatttccacg ccttcagagc
    13921 ggccaatcca gttgcgctgc atcgttttta cggtatcagg ccagtggtcc agcttatcca
    13981 gatcgcgcaa cagctcgtct gcgtaagcgg tgattttgat aaaccactgt gggatctctt
    14041 tacgctcaac tttggtgtcg caacgccagc agcagccgtc gatcacctgt tcgttggcga
    14101 gaacggtctg atcgttcggg caccagttaa cggcagaagt cttcttgtac accaggcctt
    14161 ttttatacag ctcggtgaag aatttctgtt cccaacggta gtattccggg gtgcaggtcg
    14221 cgatttcacg gctccagtca tagccaaaac ccagcgtttt gagctggttt ttcatgtacg
    14281 cgatgttgtc gtacgtccac ggcgccggcg cggtgttgtt cttcaccgcc gcgccttccg
    14341 ccggcaggcc gaaggcgtcc cagccgattg gctgcagcac gtttttgccc agcatatgct
    14401 ggtagcgggc aaccacgtcg ccgatggtgt agttacgtac gtggcccatg tgtagtcggc
    14461 cagaaggata gggaagcatc gacaggcagt aatacttctc tttgctctcg tcttcggtca
    14521 cttcaaatgt gcgcttctca tcccagtgaa gctgtacttt ggattctatc tcttccgggc
    14581 ggtattgctc ttgcatggca gccagtagtc ctgttttcga tacagctaca aatgtagctt
    14641 tagaggtggt gtttagatcc gcatagcata gcccaaacac gcacgtcaaa acagggggta
    14701 gaacatttgt cgcgctaggc gttcatgagg aggtgacgca aaatgcgaca cgactgaggc
    14761 aaattaccgc agttcctgtc accgccagat cggcctgtaa aaataaagtc atataaacca
    14821 tgcagttaaa aaatggcacg ccttttgatt agggaagaca ggactaaagc aaaggagtta
    14881 atcgtgaaaa aaaatgcagt ggtgattcac cctcaggatt gcgtcgcgac ggctattacg
    14941 gcgctcaagg ccggcgaaac cgccacaatg ttcattggcg aacgcgagat aagcgttgtg
    15001 ttacatcagg atgtgccatt tggccacaaa ttcgccatct gcgatgtgcc ttttcatggc
    15061 gaagtttata aatatggcga atccattggc cgcgccactc aggaaataaa aagtggcgac
    15121 tatgtgcacg tccacaatgt ggaaagcgaa cgcggacgtg gtgactggaa ataatataaa
    15181 acaagggaaa atgattatga gcaatgagac ttttttgggt ttccgacgcc ctgacggccg
    15241 ttttggcatc cgtaattatg tactgatttt acctaccagc gtttgtgcga ataaagttgc
    15301 ccaggatatt gcccggcagg taaaaggtgc gacatgggtg aataacgatt ttggctgctg
    15361 ccaggtggca ggcgatgcgc gtctgacgga aaagacattg attaatgtgg cgaataatcc
    15421 caacgtcggc gctattgtgg ttgtgggctt aggctgtgaa ggcgcggagc cgctgcgcat
    15481 cgcagaagag attaccgcat ttggcaaacc gacctcctgc attaccattc aggaagaggg
    15541 cggcacgctt aaatgtcagg ccagggggat ttcgctggcc cgcgactatg cgcaacaact
    15601 ctccatgcaa aaaccgcagc aagcaccggt tagcgagctg ctgctggcga tggagtgcgg
    15661 cgggtcagat acgacatcgg ggctggcgtc taacccttcc tgcggggtcg cctcggataa
    15721 gctgatacgc tgcggcggaa gctcaattct ttctgaaacg acggaattta ttggcgccga
    15781 gcatgtgatg gcgaaacgcg cggtgacgcc ggaggttggt caacagctca ttgatttagt
    15841 ggtcggctgt gaggcgcgag caaaagcgct gggcgaggat attcgcgggg gacagccgac
    15901 gccgggcagt attaaaggcg ggctgactac cattgaagaa aaatcgttag gttgtatgca
    15961 taaagcgggt catgcgccgc tacagggcgt actggaatat gccgatagtc caacgcatcc
    16021 gggcctgtgg attatggata ccccagggca ggatattgaa tctatttccg gcatggtggc
    16081 gggtggagcg cagatcgtta tttttactac cggtcgcgga acgcctgccg gtaacccaat
    16141 agcgccggta ataaaaatta cgggtaataa agcaacgtgg gaaatgatgc aggacaatat
    16201 tgatattgat gtgtccgcca ttatgtctgg cgaggcttct attacgcaaa tgggcgagga
    16261 aatttatcag gaaattttac gcgtcgcgaa tgggaaaacg actaaatcag aagatttagg
    16321 tcataacgaa ttctctattt ataagatcgc gccgacgttc tgataccaaa tcgggcagca
    16381 caagctgtcc ggttatctcc tgggaataag ctatgaaaat taaaaaaaca ctggaacgtt
    16441 ttcctggtgg tatgatggtt gtaccgctga tcatcggcgc cttgtttaaa acttttgcgc
    16501 cggaggcgct ggaaataggc ggttttgtca tctctatttc gcatggcgca atggcgattt
    16561 taggcatgtt tttagtctgt atgggcgcgg atatccagtt taaagccgcg ccgaaagcgt
    16621 tgaaaaaagg cgctgcgatc acctttgcga aatttgccag cggcgtgatt attggcattc
    16681 tggtcgggaa attttgcggc ccggatgggt tattaggtct gtcggcttta gcgattattt
    16741 cggcgatgac caactcgaac agtgggttat atgccgcgtt ggtgggggag tacggcgatg
    16801 aaaccgacgg cggcgcgatt gcggtaatat cgttgaacga tggtcccttt ttcaccatgc
    16861 tggcgttagg atcggcaggc atggtgtcga taccctttat gaatctggtg gcggttatta
    16921 ttcccattat cattggcatg attttgggca atctggatga ggacatgcgc aagtttctta
    16981 aacagggcag cgtggtaacg attccctttt ttgcctttgg gttaggatac agtattgatt
    17041 tcgcaagact tatcacggca ggttcttcag gcattttact gggactcatg acggtggcga
    17101 ttggcggatt ttttaatatt ttcgccgatc gtgtgacggg aggcagcggc gtggcaggcg
    17161 cggcggtatc caccacctct ggcaacgccg tcgcgacgcc agcggcaatc gcgctgctcg
    17221 atccgcattt taccgacctg gcgtcgacgg cggcggcgca ggtggcggcc tcgacgatta
    17281 ttaccgctct gtgcgccccc ttcctgaccg tatggataaa aaaacgctac gatcgtaaac
    17341 tgaacccagc cgccgcaggc ggttagcgtt tcggcggaaa ataaatcacg acgggcggtc
    17401 tcgcccgttt ataaaccaac aggatggtga gtgatgaata agacgaaaga tatagccgca
    17461 tctcctctct gttttgtctc tccttatccg caactggcaa aggctgccga ggcgctggtc
    17521 gcgcagttgg attacgccgt cactattcat caaacgacgc ttaatcgtat cctggatgag
    17581 ctacctttat tagagtcccg tgggcaccag gtactgatta gtcgtggcgg ctgtgcggaa
    17641 atattaaaaa agcacagtaa attaccggta gtcgaaatta aaatgtccgg ctacgacatt
    17701 cttgatgcgc ttatcccttt taaaggacaa aaaggcactg tcggtattgt cggcttttcc
    17761 agtgtgatca aaggat
//
LOCUS       DAJVBX010000084        17769 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.084, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000084 DAJVBX010000000
VERSION     DAJVBX010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 17769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17769
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.084"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            147..2267
                     /locus_tag="OPV72_002430"
     CDS             147..2267
                     /locus_tag="OPV72_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HCR9914705.1"
                     /translation="MKIISVRQRLYPALLLPLTFSPVLQAASAPNEQTMIVTATPQTV
                     SELDTPAAVSVIEGEDMRLATPRVNLSESLTSVPGLQVQNRQNYAQDLQISIRGFGSR
                     SAFGVRGIRLYVDGIPATMPDGQGQISNIDINSIQNVEVLRGPFSALYGNASGGVINV
                     TTETGRQPPTLEASSYYGSYGSWRYGLKATGAMGDGTQPGDVDYTVSTTRFTTHGYRD
                     HSGARKNLANAKLGVRLDDVSKLSLIFNSVDIKADDPGGLTESEWKADPQQAPRAEQY
                     NTRKTIKQTQAGLRYERQLSAQDDISVMAYAGERETTQYQSIPLVAQLKPAQAGGVIT
                     LQRHYQGIDSRWTHRGELGVPVTFTGGLNYENMSENRKGYNNFRLNNGTPEFGHKGDL
                     RRDERNLMWNVDPYLQTQWQLTQKLSLDAGVRYSSVWFDSNDHYIAPGNGDDSGDASY
                     HHWLPAGSLKYALTDAWNLYLAAGRGFETPTINELSYRADGQSGFNFDLKPSTNDTVE
                     VGSKTRIGNGLLTAALFQTDTDDEIVVASSMGGRTTYKNAGKTRRQGAELALDQRFAG
                     DWRVKASWTWLDATYRSNVCQGQNCDGNRMPGIARNMGFASLGFIPDEGWYAGTDVRY
                     MGDIMANDENTAKAPSYTVVGLNTGYKFNYSQLTVDIFGRVDNLFDEEYIGSVIVNES
                     NGRYYEPAPGRNYGVGINLAWQFE"
     gene            complement(2323..2988)
                     /gene="mcbR"
                     /locus_tag="OPV72_002431"
     CDS             complement(2323..2988)
                     /gene="mcbR"
                     /locus_tag="OPV72_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid/biofilm transcriptional regulator
                     McbR"
                     /protein_id="HCR9914706.1"
                     /translation="MPGTEKTQHISLTTQVENRLKHQLSIGALKPGARLITKNIAQEL
                     GVSITPVREALLRLVSSSALAVAPAQAFMVPEISLESLLEINTIRTALEEMAVVAAAG
                     KITPDREQTLNALLDEFQQALESGVMEKILLANRAFRFEIYHYADMPTLYAMIEQLWV
                     RLGPSLHFLYDNFKLDDYQNGVNLYRKLLNALVTGDKEASRHCLQNVLQQNVATIKNQ
                     YFM"
     gene            complement(3322..4359)
                     /locus_tag="OPV72_002432"
     CDS             complement(3322..4359)
                     /locus_tag="OPV72_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001517827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HCR9914707.1"
                     /translation="MKQQTNRNRRWVLASRPHGAPQMDNFRLEEDDVATPGEGQVLLR
                     TVFLSLDPYMRGRMSDEPSYAPPVEPGCVMVGGTVSRVVASNHPDYRPDEWVLSYNGW
                     QDYDISDGEGLVKLGDNPQHPSWSLGVLGMPGFTAYMGLLDIGQPKEGETLVVAAATG
                     PVGATVGQIGKLKGCRVVGIAGGAEKCRHATDVLGFDLCLDHHADNFPQQLAQACPQG
                     IDIYYENVGGKVFDAVLPLLNTSARIPLCGLVSGYNATTLPDGPDRLPLLMATLLKKR
                     IRLQGFIINQDYGHRIHEFQQEMGRWIKEGKIHYREQITDGLENAPEAFIGLLAGKNF
                     GKVVIRLADDA"
     gene            4571..5086
                     /gene="mddA"
                     /locus_tag="OPV72_002433"
     CDS             4571..5086
                     /gene="mddA"
                     /locus_tag="OPV72_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-methionine sulfoximine/L-methionine sulfone
                     acetyltransferase"
                     /protein_id="HCR9914708.1"
                     /translation="MTIRFADKADCAAITEIYNRAVLHTAAIWNDRTVDTDNRLAWYE
                     ARQLLGYPVLVSEENGVVTGYASFGDWRSFDGFRYTVEHSVYVHPAHQGKGLGRKLLS
                     RLIDEARRCGKHVMVAGIESQNAASIRLHHSLGFTVTAQMPQVGVKFGRWLDLTFMQL
                     QLDEHAAPDAC"
     gene            5086..5535
                     /locus_tag="OPV72_002434"
     CDS             5086..5535
                     /locus_tag="OPV72_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HCR9914709.1"
                     /translation="MNQSLTLIFLIAAGVGLVVQNSIMVRITQTSSTILIAMLLNSLV
                     GIVLFVTILWFKQGATGFGELVASVRWWTLIPGLLGSFFVFASISGYQNVGAATTIAV
                     LVASQLIGGLALDIARSHGVTLRAMVGPAFGALLLVIGAWLIAKRQF"
     gene            complement(5540..5773)
                     /locus_tag="OPV72_002435"
     CDS             complement(5540..5773)
                     /locus_tag="OPV72_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2526 family protein"
                     /protein_id="HCR9914710.1"
                     /translation="MSHLEEVSARVDAAIAESVIAHMNELLIALSDDAELRHEDRYVQ
                     QQRLRTAIAHHGRQYQEDRDARREQLTKGGTIL"
     gene            5997..7322
                     /locus_tag="OPV72_002436"
     CDS             5997..7322
                     /locus_tag="OPV72_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ssrAB-activated protein"
                     /protein_id="HCR9914711.1"
                     /translation="MAKSLLRSGNLDDYQAVGGGGQAVFESALQIRETLRLRKQQTMV
                     DCLAIPQLNDNGDRVDWYSPIEGQAIAWKAADEETRSRALRYLASTFESAAALSRKSL
                     QSGKTALQLFGSLLEKATQFPGENHVFLVNGKPVITFWGFVNLNENTRDDVLDCLRVT
                     EAISDIPLVEPEPQPEEKPLVEAAFSQADEPLLTSVIEPPKMPEEPAAPPVIVSEPKP
                     AAPIPVAEAKRARRLPLWSLPVAAVVIAAVATPFFWPSSSVDGASPVRTAPVATAKTD
                     VTPMPELTAHLPLHRAEVTSAPKAAPLPEAPVIIAAIPKDALVMDNTQMKLGTTRFLN
                     GSWRVSVDVKDPITGKPPSLRYQIQNNKGIARVVHGDNVVCRAEIFSGLHQTGELMIK
                     SRGNARCTDGSRYPMPEITCKAGVNDVATCTARYGDHAAIPLTFKKIGA"
     gene            7327..10308
                     /locus_tag="OPV72_002437"
     CDS             7327..10308
                     /locus_tag="OPV72_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor SrfB"
                     /protein_id="HCR9914712.1"
                     /translation="MLVNLCDYKQSVTLIANSGVQFLDFGLTPQESAHYGRFVRKTAN
                     GPLLRLDFDLTSGRYTLPGRAGGQPEVVKPESTQTLHYSLDVLDGIWLPLPFLRFNPP
                     RTFIDGPDNWARIQVRKLSEPDSAGNTHRITLAFDSQLAKNMPAALAPCENDLLNGTR
                     FALAWRDEEVADFLDQTWIDGWLRESFLQYASQVENRPEQAIQQALRSFEYQAHWLNL
                     LTLLGEQLTVPEVKFVTHTLSTPAIPVDLILDVGNTHTCGVLIEDHGDANDGLRQTAE
                     LQVRSLSEPQYLNDPLFTSRVEFSEARFGKQHFSVESGRDDAFVWPSIVRVGDEARAL
                     AMQRVGTEGSSGISSPRRYLWDETPALQDWRFSQIHGKTQREPLATAFPLMNLMNDDG
                     QPLFRLPHEERLPVFSPQYSRSTLMTHMLCEILAQALGQINSVATRLRLGFPASPRQL
                     RTLILTLPSAMPKQEREIFRQRMFEALALVWKAMGWHPQDEDFTTPKQREKSVVPVPE
                     IQMEWDEASCGQLVWLYNEAISHYAGRTESFFNALARPDRQPEPGVVPGRALRVASID
                     IGGGTTDMAIVHYQLDDGVGANVKITPHLLFREGFKVAGDDLLLDIIQRCVLPSLQTA
                     LQRAGVTDAAALLATLFGDSGRIDTQAILRQQTALQLFMPLGHAVLSAWEQSDINDPF
                     AGLHATFGDLLIRRPTSNVMNYIQQAIDHALPSGSPTFDIFNVPLQIQFSQLQEALLA
                     GQFTLTTPLHAVCEAISHYHCDILLVTGRPTCLPGVQALIRHLQPVPVNRIVWMDKYQ
                     VHEWYPFSQQGRIGNPKSTAAVGAMLCSLALDLRLPRFNFKAADIGAYSTVRYLGVLD
                     NTVNTLRDENIWYHEIDLDKPGATLDARLHFPLRGNVTLGFRQLANSRWPATPLYCLS
                     INSAELAKTIAGDGVLNVRLKLRGSSKDSAPESFILSDAWLQDGTPVAADALTLKLNT
                     LADRRHSGSHYWIDSGSVYLK"
     gene            10305..12452
                     /locus_tag="OPV72_002438"
     CDS             10305..12452
                     /locus_tag="OPV72_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence effector SrfC"
                     /protein_id="HCR9914713.1"
                     /translation="MTKPLNATQAVIEWVNNTRRYATRLDDEADALLAQLTLAAADES
                     ALNAACASSHGCVGLYGYAQSAKAHLLTTLCGNENGKLEIITPDRDYDYFSHINPGHA
                     PANMAIRFTRDIFSNESGWPLRLRLISEAELVQIFIAWTSSSPVCRQVEKSIITSRLE
                     KWQSLRQPQPVPGVTAEEVATIASFWRSCLPSARQHIDDATWQHFASLLPALDLTTRA
                     HAWALLWGEQPEITQQWLALAHMLQQTGHAGELAAPLSLLVDHFGLPAENFLTQMALT
                     ASDTQSDVVVHPVKEGRLLNAVSLSLDSLALLTRELVLTVENSVLDNVDLLDIPVAPD
                     SHPHPLWRAKLGWMLAHYRQQIQPDVLVICNALASRSQTSTAARHLLEWVNATQPQHE
                     SALPGVVWAITPQDARFATQQNLDEAVQQLMGKPGVHWGTLQALDKHSMQRLVEWLSQ
                     ATSAPQRQARLQALREQLRGRVRDLLPMCDDARLPVETVIRRLQAQAARHGDLLAGLL
                     PPVQNFEALLRTRQSREEQVSGLFNDAIDLFADEPTHASASEGHETGYQAHKMWINHL
                     RQWAHCRDNAQRLGLEPQMLNAVAEILITASYRLGLPQQLQKTMQREEVSGAQLHAII
                     GNFIAWLGYANIEEAQRPASRVQKGAAIFAATPRSTMLRLTKLDEQPVHAASRYVYDW
                     LVALYTLANENAGYRHPQDVTDVDRAQLIALIA"
     gene            complement(12497..12595)
                     /locus_tag="OPV72_002439"
     CDS             complement(12497..12595)
                     /locus_tag="OPV72_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GhoT/OrtT family toxin"
                     /protein_id="HCR9914714.1"
                     /translation="MSNKKSILRAFFPLVGATWPISFPVALLFSLF"
     gene            12733..12828
                     /gene="yncL"
                     /locus_tag="OPV72_002440"
     CDS             12733..12828
                     /gene="yncL"
                     /locus_tag="OPV72_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response membrane protein YncL"
                     /protein_id="HCR9914715.1"
                     /translation="MNVSSKTVVLINVFAAAGLLGLISLRFGWFA"
     gene            complement(12933..14378)
                     /gene="patD"
                     /locus_tag="OPV72_002441"
     CDS             complement(12933..14378)
                     /gene="patD"
                     /locus_tag="OPV72_002441"
                     /EC_number="1.2.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460556.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminobutyraldehyde dehydrogenase"
                     /protein_id="HCR9914716.1"
                     /translation="MTIWENAMQYQLLINGVLVDGEGERQSVYNPATGEVILEIAEAS
                     PVQVDAAVLAADSAFAEWGQTTPKARAECLLKLADSIEQNALEFARLESQNCGKPLHC
                     VINDEIPAIVDVFRFFAGAARCLSGLAAGEYLEGHTSMIRRDPIGVVASIAPWNYPLM
                     MAAWKLAPALAAGNCVVIKPSEITPLTALKLAALAKDIFPPGVLNVLFGRGQTVGDVL
                     TGHEKVRMVSLTGSIATGEHILRHTAPAIKRTHMELGGKAPVIVFDDADLDAVAQGVR
                     TFGFYNAGQDCTAACRIYAQRGIYDALVEKLGNAVSSLKMGAPEDKSTELGPLSSLAH
                     LKRVTAAVEEAKALSHIRVITGGSQTEGKGYYFAPTLLADAKQEDAIVQREVFGPVVS
                     ITVFDDEDQVLRWANDSRYGLASSVWTQDVGRAHRLSARLQYGCTWINTHFMLVSEMP
                     HGGQKQSGYGKDMSLYGLEDYTLVRHIMVKH"
     gene            complement(14493..15917)
                     /locus_tag="OPV72_002442"
     CDS             complement(14493..15917)
                     /locus_tag="OPV72_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HCR9914717.1"
                     /translation="MKKYQRLAEQIREQIASGVWQPGDRLPSLREQVASSGMSFMTVG
                     HAYQLLESQGRIIARPQSGYYVAPHPVCRSVATAAHVIRDEAVDINTYIFEMLQASRD
                     TSVVPFASAFPDPRLFPLPQLNRSLAQVSKTETAMSVIENLPPGNAELRYAIARRYAQ
                     QGITVSPDEIVITAGALEALNLSLQAVTAPGDWVVVENPCFYGALQALERLRLKALSI
                     PTDVKEGIDLMALEQALQEYPVKACWLMTNSQNPLGFTLSAEKKARLVALLTHHNVTL
                     IEDDVYSELYFGREKPLPAKAWDRDDTVLHCSSFSKCLVPGFRIGWVAGGSHARQIQR
                     LQLMSTLSTSSPMQLALVDYLSTRRYDAHLRRLRRQLAERKQQAWQTLLRHLPAEVKI
                     HHNDSGYFLWLELPEQLDAGELSAKALEHLISIAPGKMFSTSGAWTRFFRFNTAWHWG
                     EREEQAVKQLGSLIREMLSAKSLV"
     gene            complement(16053..16823)
                     /locus_tag="OPV72_002443"
     CDS             complement(16053..16823)
                     /locus_tag="OPV72_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HCR9914718.1"
                     /translation="MVKCVSSFLLFSLLSVQAISAENHIDLHQPKDFVDITTVAPDVQ
                     VDMRYFTSHNFIGRPIKGYNAPVCLLTRPAANAVKQVADRLRPFGLTLKIYDCYRPQS
                     AVNDFIAWAKDPSQNQMKNEFYPQVEKNRLFEEGYLAARSGHSRGSTLDLTIVPLDSK
                     IPIYHPGRPLVNCTASAAQRSPDNSLDFGTGFDCFSPLSHPDNVMLTAQQRANRLLLQ
                     TLMRDAGFTPLDTEWWHFSLTHEPYPNTWFDFPVKQRP"
     gene            complement(17086..17316)
                     /locus_tag="OPV72_002444"
     CDS             complement(17086..17316)
                     /locus_tag="OPV72_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_448018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914719.1"
                     /translation="MAMTSRPNYLGSRGILCVCTTAVNRNFSALSPTIDVFLTNCLPD
                     YIVVLSLAKQCYLVMEGDNNCTIDYQISFLVR"
     gene            complement(17349..17747)
                     /locus_tag="OPV72_002445"
     CDS             complement(17349..17747)
                     /locus_tag="OPV72_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine dipeptidase"
                     /protein_id="HCR9914720.1"
                     /translation="MKKSDGEIHEKTASWGILQSEWLRKCGRLLLLLLYRFVIGWAFF
                     QLLAMIVAGIFLLGVLLFHPIIFVQTIAITEKLNHASLDLWHILKLCLWHYGIIAGFI
                     FMAECTLSKSIRQVQRLSKKFGAQDFSSRP"
BASE COUNT         4188 a         4809 c         4557 g         4215 t
ORIGIN      
        1 gcttttcctc gcctgcgaat gtcatggctc ttaaataccg cacattttct taacttaatg
       61 tgcgattaaa atttcaaaac tttacatatt gactaccctt aatgtcacgt tttccgttga
      121 tacgcttaca tttatccggc attttcatga aaattatttc cgttagacag cgactttatc
      181 ccgccctctt attgcctctg accttctccc cggtccttca ggccgccagc gcgcccaatg
      241 aacaaaccat gatagtcacc gcaacgccgc aaaccgtatc cgagctggat acacctgccg
      301 ccgttagcgt cattgaggga gaagacatgc gtctggcgac gccgcgcgtt aatttatctg
      361 agtctttaac cagcgtcccg ggattgcagg tgcagaaccg gcagaactac gcgcaggatc
      421 tgcaaatctc tatccgtgga tttggctcgc gttccgcctt tggcgtgcgc ggcattcgtc
      481 tgtatgttga tggcattccc gccaccatgc cggatggaca aggccagatt tcaaatattg
      541 atattaacag catacaaaac gttgaagtgt tacgcggccc cttctcagcg ctatacggca
      601 atgcttccgg cggcgtgata aatgtcacca ccgaaaccgg gagacagccg cccacccttg
      661 aggccagcag ctactacggc agttatggaa gctggcgcta tgggttaaaa gccacgggcg
      721 cgatggggga cggcacacag cctggcgacg tggattacac ggtatcgact acccgtttca
      781 ccacccacgg ctaccgcgat cacagcggcg cgcgaaaaaa tctggctaat gccaaactgg
      841 gcgtgcgcct tgacgatgtc agtaaacttt cgctgatttt taatagtgtg gacattaagg
      901 cggacgatcc cggcggactt accgaatctg aatggaaagc cgatccgcag caggcgccgc
      961 gcgctgaaca gtacaatacg cgtaaaacca tcaaacaaac tcaggcagga ttgcgttatg
     1021 aacgtcagct cagcgcgcag gatgatatca gcgtgatggc ctacgccgga gagcgggaaa
     1081 ccacgcaata ccagtctatt cccctggtgg cacagctaaa accagcccag gctggcggcg
     1141 taattacact gcaacgccac tatcagggaa ttgattcccg ctggactcac cggggagaat
     1201 taggtgtgcc ggtcaccttc actggcgggt taaactatga aaacatgagc gaaaaccgca
     1261 agggttacaa taatttccgt ctcaacaacg gcacccctga gttcgggcat aaaggcgatt
     1321 tacggcggga tgagcgtaac ctgatgtgga atgtcgatcc ttatctgcaa acccagtggc
     1381 agcttacgca aaaactctcg ctggatgctg gcgtgcgcta cagttccgtg tggttcgatt
     1441 ctaacgatca ctatatcgcg cccggcaatg gcgatgacag cggcgacgcc agctatcacc
     1501 actggctacc cgccggatcg ctaaaatatg cgttaactga cgcctggaat ctctatcttg
     1561 ctgccggtcg cggatttgaa actcccacta tcaatgaact ttcttatcgc gctgacggcc
     1621 aaagcgggtt caactttgac ctcaaaccgt cgaccaatga tacggtggaa gtcggcagta
     1681 aaacgcggat tggcaatggc ttgttgaccg ccgcgttatt tcaaaccgat accgatgatg
     1741 aaattgtcgt cgccagtagt atgggaggac gcactaccta caaaaacgcg ggcaaaacgc
     1801 gccgccaggg cgcagagctc gcgttggacc agcgcttcgc cggcgactgg cgggtgaaag
     1861 catcatggac ctggctggat gcgacctatc gcagtaacgt ttgtcagggg caaaactgtg
     1921 atggaaaccg gatgcccggc atcgcccgta atatgggatt cgcctcatta ggttttatcc
     1981 cggatgaggg gtggtacgcc ggaacagacg ttcggtatat gggcgatatc atggccaatg
     2041 atgaaaatac cgccaaagcg ccttcgtata ccgttgttgg actaaataca gggtataaat
     2101 ttaattacag tcagcttacc gtcgatattt ttgggcgggt agataatcta tttgatgaag
     2161 aatatatcgg ttcggtgatc gttaatgaat ctaatggccg atattatgag ccagcgccag
     2221 ggcgtaacta tggcgtgggg attaatctgg catggcaatt tgaataaata tccggcaata
     2281 gcggggcatc cccgctattg attagtcata gtttcatgaa agttacatga agtactgatt
     2341 tttaatcgtc gctacgtttt gttgcaaaac gttctgtagg cagtggcgac tggcttcttt
     2401 atcaccagtc actaacgcat taagcaattt tctgtacaga ttaacgccgt tttgataatc
     2461 atcaagttta aaattatcat ataaaaaatg cagacttggc cccaggcgta cccataattg
     2521 ctcgatcatg gcatacagcg ttggcatatc cgcgtagtgg tagatctcaa agcggaatgc
     2581 gcggttggcc aaaagaattt tctccataac gccactttcc agcgcctgtt gaaattcatc
     2641 taatagcgca ttcagcgtct gctcgcgatc cggggtaatc ttacccgcag cggcgaccac
     2701 cgccatctcc tccagggcag tacgaatcgt attaatttcc agcaaacttt ccagcgagat
     2761 ctccggcacc ataaacgcct gtgctggcgc caccgccaaa gcactggaag agaccagcct
     2821 taacagggcc tcacgcaccg gcgtaatact gacgcctaac tcttgagcga tatttttagt
     2881 gataagcctt gcgcctggtt ttaatgcgcc aatagacaat tgatgcttta accgattttc
     2941 aacctgtgtg gtcaggctta tatgttgtgt tttttccgta cccggcattt tccttccttc
     3001 acctcttggc agaacaacat cgcaatcgag tcccgaagaa gtttcggaac ttaattgtaa
     3061 aaaagataat ccagacctga acggccaaat aaataaaagt gataatttac ttgcgtgata
     3121 ttctcatctt ttacaacaat acaggtttct ttatggcaac cgttttatct ccgtcattcc
     3181 ttcatgtatc gagatttttg accggttcag gccgctgagg gagataagct gccccaccgc
     3241 gatctgaatg atgaatataa gtaaagccgc aattttaaaa tttgcacatt tttatggcga
     3301 cataatgccg ccattttttc tttacgcatc gtccgctaaa cgtatcacga ctttgccaaa
     3361 gttcttcccc gccagcagcc ctataaacgc ttctggcgca ttttccagcc catcagtaat
     3421 ctgctcccgg taatgtattt tcccttcttt gatccaacgc cccatttctt gctgaaactc
     3481 atgtatccgg tgaccatagt cctggttgat gataaaacct tgcaggcgaa tacgcttttt
     3541 aagtaatgtc gccatcagca gtggcagtct gtctggaccg tccggcaacg ttgtcgcatt
     3601 gtagccgctg accagaccgc agagcggaat ccgcgccgac gtattcagta gcggtaagac
     3661 ggcgtcaaag actttaccac cgacattctc ataatagata tcgataccct gcgggcaggc
     3721 ctgcgcaagc tgttgtggga aattatcagc gtgatgatca aggcacagat caaatcccaa
     3781 aacgtctgtc gcatgacggc atttttccgc gccgccggca atacccacga cccggcagcc
     3841 cttcagcttg ccaatttgcc caaccgttgc gcctacgggg ccggtggcgg cggcgacaac
     3901 cagcgtttcg ccctctttcg gctggccgat atccagtaac cccatatagg cggtaaaccc
     3961 cggcatccct aaaactccca acgaccagga aggatgttgc ggattatcac ccagctttac
     4021 caacccttcg ccatctgaaa tgtcataatc ctgccaacca ttgtaactca acacccattc
     4081 gtctggtcgg taatcaggat gattcgacgc gacaacgcga ctgaccgtac cgccaaccat
     4141 aacgcagcca ggttcaactg gcggcgcata agagggttca tcgctcatgc ggccacgcat
     4201 ataagggtcg agtgataaaa aaacggtacg caatagcacc tgcccttcac cgggcgtcgc
     4261 gacgtcatct tcttcgaggc ggaagttatc catctgcggc gcgccgtggg gacgcgaggc
     4321 caaaacccaa cgacgatttc ggttggtctg ttgcttcatt ctattctcct catgcctggc
     4381 ataatccatc aataatagtc gaacattagc tttctgaggg agttaaacac tctcagatat
     4441 caggctgtgc gcttttatga acgactttct ttcccctctc gctaaatatg aattcttgcg
     4501 ctaattcgtt gatttatgcc gccttcaata gtatttctaa cactatcgta aacattccct
     4561 ggggttccct atgacgattc gctttgccga taaagcagac tgcgccgcga ttaccgaaat
     4621 ctataaccgt gcggtattac atactgcggc catctggaac gatcggacgg tcgatacgga
     4681 taatcgcctt gcctggtatg aggcccgtca attactgggc tatccggtgc tggtaagcga
     4741 agaaaatggc gtggtgactg gctatgcatc atttggcgat tggcgcagtt tcgacggttt
     4801 tcgctatacc gtcgagcact cggtttatgt tcatccggcg caccagggga aaggactggg
     4861 gcgaaaactg ctcagcagac tgatcgacga agcccgacgc tgcggcaagc atgtgatggt
     4921 ggccggtatt gagtcacaga atgccgcctc gatacgcctg catcattcgc tgggatttac
     4981 cgtcaccgcg caaatgccgc aggtcggcgt aaaatttggc cgttggttag atcttacgtt
     5041 tatgcagctc cagcttgatg aacacgccgc gccggacgcc tgctgatgaa ccagtcgctg
     5101 acgcttatct ttttgatcgc cgccggcgtc gggctggtgg tacaaaacag tattatggtg
     5161 cgtattacgc agacatcatc gacgattctg atcgctatgc tgttgaactc gctggtaggg
     5221 atcgttttat ttgtgacgat attgtggttt aagcaaggcg ctacgggctt cggcgagctg
     5281 gtcgccagcg tgcgctggtg gacattgatc cccggtttgc tggggtcatt ttttgtattt
     5341 gccagcatta gcgggtatca gaacgttggc gccgcgacga ctatcgcggt actggtcgcc
     5401 agtcagttaa tcggcggact ggcgctggat attgcgcgta gccacggcgt cacgttacgc
     5461 gcaatggtcg ggccggcgtt tggcgcgctg ttgctggtca ttggcgcatg gctgattgcg
     5521 aagcgccagt tttaatgggt tacaggatcg tgccgccttt ggtgagctgt tcgcggcgcg
     5581 cgtcccgatc ttcttgatat tgcctgccgt gatgcgcgat agccgtgcgt aaacgctgct
     5641 gctgcacata acgatcttcg tgacgtaatt cagcgtcatc gctcaaggca atcagcaatt
     5701 cattcatatg ggcaattacg ctctccgcga tggcggcatc cacgcgggcg ctcacttcct
     5761 ccaggtgcga cataagctct cctactcttt attctgtaat agcatgattc gcctattata
     5821 cgcgttattg tcgcccgatg cggtcattcg ccgccgccac tctgatttaa cttacgtcaa
     5881 gtgaaaacac ggggcttaat agaccgagaa ttcgcgcctt tttgcctttc ttccgccgtt
     5941 tgcttgcgta tagaccccgt aaagtagacg cgtgaagaag tctaagggat aacaacgtgg
     6001 caaaatctct cttgcgcagc ggcaatctgg atgattatca ggccgtgggc ggcggcggtc
     6061 aggccgtatt tgaatcagca ttgcaaattc gcgaaacgct tcgtctgcgt aaacagcaga
     6121 cgatggttga ctgtctggcg attccgcaac ttaacgataa tggcgatcgg gttgactggt
     6181 attcgccgat tgaaggtcag gcgatagcgt ggaaagcggc tgacgaagag acacgttctc
     6241 gggctttacg ttatttagcc agcacttttg aaagcgcggc tgcactcagt cgcaaaagtc
     6301 tgcaatccgg taaaacagcg ctccagctat ttggttcgct acttgagaag gcgacgcaat
     6361 ttcccggcga aaatcatgtt ttcctggtta acggcaaacc ggttatcacc ttctggggat
     6421 tcgttaatct caacgaaaat acacgcgatg atgtgctgga ctgcctgcgg gtaaccgagg
     6481 cgatctccga catccctctg gtcgagccgg agccgcagcc cgaagaaaag ccgctggtag
     6541 aggcggcgtt tagtcaggcg gatgaacctt tgttaacgtc tgtcattgag ccgccgaaaa
     6601 tgccggagga acctgctgcg ccgcccgtta tcgttagcga gccgaagcct gccgcaccta
     6661 tcccggttgc tgaggcgaaa agagctcgcc gtctaccgct gtggagctta cctgtcgctg
     6721 ccgtggttat cgccgccgtc gccacgcctt ttttctggcc atcttcatcc gttgacgggg
     6781 cctctcctgt tcgcaccgcg cctgtcgcta ccgcgaaaac tgatgttacc ccaatgcctg
     6841 aactcaccgc gcatttgccg ctgcatcgcg ctgaggtgac gtccgccccc aaagcggcgc
     6901 cgctgccgga agcgcctgtt atcattgccg ctatccccaa agacgcgctg gtgatggaca
     6961 atacgcagat gaagcttgga accacgcgct ttttaaacgg tagctggcgg gtcagcgtgg
     7021 atgtcaaaga tccgattacc ggcaagccgc cctctctgcg ttatcagatc caaaataaca
     7081 aaggcatcgc gcgcgtagta catggcgata acgtggtttg tcgggcggaa attttctctg
     7141 gtctgcatca aacgggcgag ctgatgatta aaagtcgcgg caatgcgcgc tgcaccgacg
     7201 gttcacgtta tccgatgccg gaaattacct gtaaagcagg cgtcaatgac gtcgcaacct
     7261 gtaccgcccg ttatggcgac cacgcggcaa ttccgttgac gtttaaaaag ataggtgcct
     7321 gattttatgt tggtcaatct gtgtgattac aaacagagcg tcacgctcat tgcaaacagt
     7381 ggcgtccagt ttcttgattt tggcttaacg ccgcaagagt cggcccacta cggacgtttt
     7441 gtgcgcaaaa cggcaaacgg cccgctactg cgcctcgatt ttgatctgac cagcgggcgc
     7501 tacacgttgc caggacgtgc tggcggccaa cccgaagtcg tgaaaccgga aagcactcag
     7561 acgctgcact attctctgga tgtactcgac gggatctggc ttcccctgcc gttcctgcgt
     7621 tttaatccgc cgcgtacctt tattgacggg ccggataact gggcgcgcat tcaggtacgt
     7681 aaactcagcg agccagatag cgccggaaac acacaccgca tcaccctcgc cttcgacagt
     7741 cagctggcaa aaaatatgcc tgcggcgttg gcgccttgcg aaaacgatct gctcaatggc
     7801 acacgttttg cgctcgcctg gcgcgatgaa gaagttgccg attttcttga ccagacatgg
     7861 attgacggct ggctgcgcga gtcgtttctt cagtatgcct cacaggtgga aaaccgtccg
     7921 gaacaggcca ttcaacaagc gctgcgtagt tttgagtatc aggcgcactg gttgaattta
     7981 ctgacgctgt taggcgaaca gcttacggtg ccggaagtaa agtttgtgac acatacgtta
     8041 agcacgcccg caatcccggt cgatctgatt ctggatgtcg gcaatacgca tacctgcggc
     8101 gtcttgatcg aggatcatgg cgatgcgaat gacggcttac gccagacggc agagcttcag
     8161 gtgcgttctt taagcgagcc gcagtatctg aacgatcctt tatttaccag ccgggtggaa
     8221 ttctcagaag cgcgctttgg caagcaacac ttttctgtcg aaagcggacg agacgacgcc
     8281 tttgtctggc cttctattgt gcgtgtgggc gacgaggctc gcgcccttgc tatgcagcgt
     8341 gtgggcaccg aaggcagcag cggtatctcc agcccgcgcc gctacctgtg ggatgaaacc
     8401 cccgccttgc aggactggcg ctttagccag atccacggta aaacgcagcg cgaaccgctt
     8461 gccaccgcgt ttccgctgat gaatctgatg aacgacgacg gacagccgtt attccgcctg
     8521 ccgcatgaag aaaggctacc ggttttttcg ccgcaataca gccgtagcac cttgatgacg
     8581 catatgttgt gcgaaattct ggctcaggcg ctggggcaaa ttaacagcgt cgccacccgg
     8641 ctgcggctcg gctttcccgc ctcgccgcgc cagctacgta ccctgatttt aacgctgcct
     8701 tccgccatgc cgaaacagga gcgagaaatt ttccgccagc gaatgtttga agcgctggcg
     8761 ctggtctgga aagccatggg ctggcatccg caggatgagg atttcaccac gcctaagcag
     8821 cgtgaaaaaa gcgtggtgcc agtacctgaa atacagatgg aatgggacga agcaagttgt
     8881 ggccaactgg tatggcttta taacgaagcc atttcgcatt acgccgggcg taccgaatcc
     8941 ttttttaatg cgctggccag accggatcgc cagcctgaac ccggcgtcgt ccccggacgc
     9001 gcgttgcgcg tggcatcgat tgatatcggc ggcggcacga cggatatggc gatcgttcac
     9061 tatcagttag atgacggcgt gggggccaat gtaaaaatta cgcctcatct cctgtttcgc
     9121 gaaggtttta aagtcgccgg ggacgatctg ctattggata tcattcagcg ctgcgtactc
     9181 ccttccctgc aaacggcgtt gcaacgggca ggcgttacgg atgccgccgc cctgctggcg
     9241 accttatttg gcgattcggg acgaattgat actcaggcca ttttgcgcca gcaaacggcg
     9301 ctgcaattat ttatgccgct gggccacgcg gtactttccg cctgggagca aagcgacatt
     9361 aacgatccgt ttgccggttt acatgcgaca tttggcgatc tgctgatccg ccgcccaacg
     9421 agcaacgtga tgaactatat ccagcaggcg atcgatcatg ccttaccgtc tggttcgccg
     9481 acatttgata tattcaatgt gccattgcaa atccagttta gccagcttca ggaggctctg
     9541 ctggccggtc agtttacgct gacaacgccg cttcatgcgg tctgcgaagc gatctcccac
     9601 tatcactgcg atatcttgct ggtgacgggg agaccgacct gtttacctgg cgtacaggcg
     9661 ctcatccggc acttacaacc ggtgccggtt aatcgcattg tgtggatgga taagtatcag
     9721 gtacatgaat ggtatccctt cagtcaacaa gggcgtatcg gcaatccaaa atccactgcc
     9781 gcggtgggcg cgatgttatg cagcctggcg ctggacttac gcctgccgcg tttcaatttt
     9841 aaagcggctg atatcggcgc gtattcgact gtgcgttatc tcggcgtact ggataatacc
     9901 gttaatacgc ttcgcgatga aaacatctgg tatcacgaga tcgatttgga taaacccggc
     9961 gcaacgctgg acgcacgcct gcattttccg ctacgcggca acgtgacgtt gggctttcgt
    10021 caacttgcga acagtcgctg gcctgcgacc ccactctatt gcctgagcat taattccgcc
    10081 gaactggcga aaaccatcgc tggcgacggc gtactgaatg tccgactgaa attacgcggc
    10141 agtagcaaag atagcgcccc ggaatcgttc atattaagtg atgcctggct ccaggacggg
    10201 acgccggtcg ccgccgatgc gctgacatta aaattgaata cgctggctga ccgccgccac
    10261 agcggcagcc actactggat agatagcggg agtgtatacc tgaaatgaca aaaccgttaa
    10321 acgccactca ggctgttatc gagtgggtta acaacacgcg ccgttacgca acgcgactgg
    10381 atgacgaagc cgacgctctg ctggcgcaac ttacgcttgc cgcggcggat gagtcagcgc
    10441 tcaacgccgc ctgcgcatca tcacatggct gcgttggtct gtacgggtat gcgcaatccg
    10501 caaaagcgca tctgttaacg acgctatgcg gtaacgagaa tggcaagctg gaaattatca
    10561 cgccggaccg tgactatgat tatttcagcc acatcaatcc gggtcatgcg ccagcgaata
    10621 tggctattcg ctttacgcgc gacatttttt caaacgagag cggctggccg ttgcgcctgc
    10681 gcttgatcag tgaagccgaa ctggtgcaga tctttattgc ctggaccagc tcgtcccccg
    10741 tttgtcgcca ggtcgaaaaa tccattatca catcacgcct ggagaaatgg caatcgcttc
    10801 gccaaccgca gcccgtcccc ggcgttaccg ctgaagaggt agcgaccatc gcgagtttct
    10861 ggcgctcttg cctcccgtcc gccagacaac atattgatga tgcgacatgg caacactttg
    10921 cctcgctctt gcctgcgctg gatctcacga cacgggcgca cgcctgggca ttactgtggg
    10981 gagagcaacc agagatcacc cagcaatggc tggcgctggc gcatatgttg caacaaaccg
    11041 gccatgccgg ggaactggcg gcgccgctca gcctgctggt cgatcatttt ggcttaccgg
    11101 cggaaaactt cctgacgcaa atggcgctaa ccgccagcga tacgcaaagc gatgtggtgg
    11161 tgcatccggt taaggaaggc cgactgctca atgcggtcag cctttcgctt gattctctgg
    11221 cgctgcttac ccgcgaactg gtgctaaccg ttgaaaatag cgtactggat aacgttgatt
    11281 tactggatat tccggtcgcg ccagacagtc atcctcatcc gttatggcgg gcgaaattag
    11341 gctggatgct ggcccattac cgtcagcaga tacagcccga tgttctggtg atttgcaatg
    11401 ctctggcatc tcgctcgcaa acgtccactg ccgcccgtca cttactggag tgggttaacg
    11461 ccacgcagcc gcagcatgaa tcagcgttac ccggcgtcgt ctgggctatt actccacagg
    11521 atgcccgttt tgccacccag caaaatctgg atgaagccgt ccagcagttg atgggtaaac
    11581 ctggcgtgca ttggggaacg ttgcaggcgc tggataaaca cagtatgcag cgtttggtgg
    11641 agtggttatc gcaggcgaca tcggcaccac agcgacaggc gcgcttacag gcgttacgcg
    11701 aacaactgcg aggccgcgtg cgcgatctgt taccgatgtg tgatgacgcg cggctaccgg
    11761 ttgaaaccgt gatccggcgt cttcaggccc aggccgccag acatggcgac ctgctggccg
    11821 ggctgttacc gccggtacag aatttcgaag cgttgctgcg cacccgacag tcgcgagaag
    11881 aacaggtcag cggtttattt aatgacgcga tcgatctctt tgccgacgaa ccaacgcacg
    11941 cttcagcgtc agaaggtcat gaaacaggct accaggcgca caaaatgtgg atcaatcatc
    12001 tgcgccagtg ggcccactgc cgggataatg cgcagcgtct gggactggaa ccgcagatgc
    12061 tcaacgccgt ggcggagatt ttaattaccg ccagctatcg cctcggttta cctcagcagt
    12121 tacagaaaac catgcagcgc gaggaggtga gcggcgcgca gcttcatgcc atcattggta
    12181 acttcatcgc ctggctcggc tacgccaata tcgaggaggc ccaacgcccg gccagccgcg
    12241 ttcagaaagg cgcagccatt ttcgccgcaa cgccgcgttc gacaatgttg cgtctaacaa
    12301 agcttgacga acagcccgtt cacgccgcca gccgctatgt ctatgactgg cttgttgcgc
    12361 tgtataccct ggccaatgag aacgcaggat atcggcatcc gcaggacgtt accgacgtag
    12421 acagagcgca attaattgcc ctgatagcct gacctggcgg aaaaaccatg cccggtaacc
    12481 tgtatcgggc ttgaggtcag aaaagcgaaa acagcaatgc gacggggaaa cttatcggcc
    12541 atgtcgcgcc aaccagagga aaaaacgcgc gcaatatgct ctttttattt gacacacatc
    12601 aaggtttatc agccttaaca gcaaaacgtt ctcaatgcac ggctccgctc acagaatatc
    12661 ctgtttacgt attattgcgg atctcgccaa cccgtactat acccataggg gttatgatga
    12721 aaggtggcga aaatgaatgt ttccagtaaa accgtcgtgc tgattaatgt ctttgctgct
    12781 gcaggacttt tgggtctgat ctcgttgaga ttcggctggt ttgcttgagg tgttcaacct
    12841 ttgagtactt gctgcgcatg ttggcgggga ggtccccctc tccgccgaca cccgcctatt
    12901 ttttcacgat ttttctgaac agtaaatgat ccttaatgct taaccatgat gtggcggaca
    12961 agggtgtagt cttccagacc atacaatgac atatctttgc cgtatcccga ctgtttttgc
    13021 cctccatgcg gcatttcgct aaccaacatg aaatgggtat taatccaggt acagccatac
    13081 tgcaatctgg cgctaagccg gtgcgcccgc ccgacgtcct gagtccagac ggaggatgcc
    13141 agaccatagc gagaatcgtt ggcccacctc agaacctgat cttcatcatc aaagacggtt
    13201 atactgacca ccgggccgaa gacctcgcgt tgcacgatgg catcttcctg ttttgcgtct
    13261 gccagcaacg tcggagcgaa atagtaacct ttaccttccg tttgacttcc accagtaatc
    13321 acacggatat ggctgagggc cttcgcctcc tctacagccg ctgtgacgcg cttcaggtgc
    13381 gccagcgaac ttaacggccc cagctctgtc gacttatcct ccggcgcgcc cattttcagg
    13441 ctgctcaccg cgttccctag cttttcgacc agcgcatcat agataccgcg ctgcgcgtat
    13501 atacggcacg ccgcagtaca atcctgtccg gcattataga aaccgaaagt ccggacaccc
    13561 tgcgccaccg catccagatc ggcgtcatca aaaacaatca ccggggcttt accaccgagt
    13621 tccatatgcg tacgttttat cgctggcgca gtatggcgca gaatatgctc cccggtcgcg
    13681 atagaaccgg ttaaagagac catgcgtact ttttcatggc cggtcaatac atcaccaaca
    13741 gtttgccctc gtccgaacag gacattgagc acccccggcg gaaagatatc cttcgccagc
    13801 gcggcaagtt taagcgccgt cagcggcgtg atttcagaag gcttaatcac cacgcagtta
    13861 cctgccgcca gcgctggcgc cagcttccag gccgccatca tgagcggata attccacggc
    13921 gcgatagagg caaccacgcc aatcggatcc cggcggatca tcgacgtatg tccttccaga
    13981 tattcgcccg ccgccagccc actcaaacaa cgggccgcgc cggcaaaaaa gcgaaagaca
    14041 tccacgattg ccggaatttc atcattaatt acgcagtgca aaggcttacc gcagttttgc
    14101 gattcaagcc gggcgaactc aagggcgttt tgctcgatgc tgtccgccag ttttaacaga
    14161 cattccgccc gtgctttggg tgtggtctgc ccccattcgg caaacgcgct atcggcggcc
    14221 agcactgcgg cgtcaacctg cacgggcgac gcttccgcaa tctcaagtat gacctcgcct
    14281 gtcgccgggt tataaacgga ctgcctttct ccctcgccgt ccaccagcac gccattaatc
    14341 agtaattgat attgcatagc attttcccat atcgtcatta atcgatttcc ggcgaacggg
    14401 ccgccgcttt cctaaaaata gacggcgcgc cagatgctca cccggcacac tcgggaaatt
    14461 tagtcaggtt gtgagctgac acgcattcca cctcacacaa ggcttttagc gctcagcatc
    14521 tcgcgaatca ggcttccaag ctgttttacg gcctgttctt cccgttctcc ccaatgccat
    14581 gcggtgttaa aacgaaagaa acgcgtccag gcgccggacg ttgaaaacat tttccctggc
    14641 gcgatactga taaggtgttc aagcgctttg gcgctaagtt cgccggcatc aagctgctca
    14701 ggtagctcca gccaaagaaa ataaccgcta tcgttatggt gaatttttac ttccgccggg
    14761 agatggcgca aaagggtttg ccaggcttgc tgtttacgtt cggcaagctg ccttcgcaat
    14821 cggcgcagat gcgcgtcata tcgacgtgtc gagagataat ctactaacgc caattgcatg
    14881 ggagaactgg tggataatgt gctcattaac tgcaaacgct gaatttgtct ggcatggctt
    14941 cctcccgcaa cccagccaat gcgaaaaccg ggaaccagac atttggaaaa agacgaacaa
    15001 tgcaacacgg tatcgtcgcg atcccatgct ttggcaggaa gaggtttctc gcggccaaag
    15061 tagagttcgc tataaacatc gtcttcaatt agcgtcacgt tatggtgcgt gagtaacgca
    15121 accagccgcg cttttttctc agcactcagc gtgaacccta acggattctg gctgttggtc
    15181 attaaccagc acgctttcac cggatattcc tgtaacgcct gttccagcgc cataagatcg
    15241 ataccttctt taacatcggt aggtatcgac aacgctttca ggcgcaatcg ctccagggcc
    15301 tgtagcgcac cgtagaaaca ggggttctcc accaccaccc agtctcccgg tgccgtcacc
    15361 gcctgtaaac taagattcaa cgcttccagc gcgccggcgg taatgacaat ctcgtcagga
    15421 gaaacggtaa tcccctgctg cgcgtaacgg cgtgctatcg catagcgcaa ttctgcatta
    15481 cctggcggca agttttcgat gacgctcatt gccgtctcgg ttttactgac ctgcgccaga
    15541 gagcggttca attgcggcaa gggaaacaga cgcggatcgg gaaacgctga ggcaaagggc
    15601 accacagagg tatcacggct cgcctgcagc atctcaaaaa tataggtatt gatatctacg
    15661 gcttcatccc gaataacgtg cgctgccgtc gcgactgacc gacaaaccgg atgcggcgcg
    15721 acataataac cagattgcgg acgggcgata atccgtccct gactttccag caactggtac
    15781 gcatgaccga cagtcataaa actcatgccg ctactggcga cctgctccct cagcgagggt
    15841 aatcgatcgc cgggttgcca aacgccagag gcgatttgtt ctctaatttg ctccgccaga
    15901 cgttgatatt ttttcattat tcgttctcat tgagcgctgc ttgcaggtgg caaccgcagt
    15961 gtatatcagt tgttaaaatt aacaatgatt tgctaactgt tatggtgctt tccaacaggc
    16021 gtaatgatta gatttcgcaa caaaacgccg tttcagggtc tctgcttaac gggaaagtca
    16081 aaccaggtgt tcgggtatgg ttcatgagta agggagaagt gccaccattc agtatccagt
    16141 ggcgtaaaac ccgcatcacg catcaatgtt tgtaataaca acctatttgc gcgttgctga
    16201 gcggtaagca tgacattatc gggatgggat aacggactaa aacagtcaaa gcctgtacca
    16261 aaatccagac tattatctgg cgagcgttgc gccgcggacg cagtacaatt caccagtggt
    16321 cgtccgggat ggtatatcgg tattttactg tcaagtggaa caatcgttag atcaagcgta
    16381 cttccccgac tgtggccgga tctggcggca agataacctt cctcaaacaa acgatttttc
    16441 tctacctgcg gataaaattc gtttttcatt tggttttgag aaggatcttt ggcccacgcg
    16501 ataaagtcat tcactgcgct ttgcggacgg tagcaatcat atatttttaa ggtaagtccg
    16561 aaggggcgta aacgatcggc gacctgcttt actgcgttcg cggctggtcg tgttaacagg
    16621 caaacaggcg cgttatagcc tttaatgggg cgaccaataa agttatggga agtgaagtat
    16681 cgcatgtcta cctgtacgtc gggggcgacc gtagtaatat cgacaaagtc ttttggctgg
    16741 tggagatcaa tatggttttc agctgatatt gcctgaacgg acaacaggct gaacaggagg
    16801 aaagaagata cgcattttac catatgttac acctcgcgag agtcacaggg gtgattatgt
    16861 atttgagcag gtaaagatta gcggacagcg cttaaacaga tggttaaaat aaacatcatt
    16921 ccccccctgt aatctgtgcc ttattacaaa cggagaggtt atattttgct tattatggcc
    16981 attacgccgc ctgttctata cccaaaataa ttcgagttgc ttaaaggcgg caagggagtg
    17041 agtccccagg agcacagata acgatatgtt ttcacaaagg cgagtctacc tgaccagaaa
    17101 ggatatttga taatcaatag tacagttgtt gtcgccttcc ataactaaat aacattgttt
    17161 cgccaaagat aagaccacta tatagtcagg aaggcaatta gtgaggaaca cgtcgattgt
    17221 cggcgataat gcactgaaat tacgattcac tgcagttgtg caaacacata gaatccccct
    17281 cgaaccgaga taattcggtc tgctggtcat agccattatt cagtaagacc gcaggttgca
    17341 gcggcggatc acgggcgtga agaaaaatcc tgtgccccaa attttttgga caagcgctga
    17401 acctgccgta tacttttact taacgtacac tccgccataa aaataaaccc tgcgatgata
    17461 ccgtaatgcc acaggcataa cttaaggata tgccataaat caagcgaagc atgatttaac
    17521 ttctcagtaa ttgcgatagt ctgtacaaat attatgggat gaaataataa gacgcctaac
    17581 aaaaatatcc ctgccacgat catggcaagt aactggaaaa aagcccatcc gataacgaaa
    17641 cggtaaagta acagcaataa tagccgtcca cattttctta gccattctga ctgcaaaatg
    17701 ccccaggatg ctgtcttttc gtgaatttca ccatctgatt tcttcatttt gagcctcctc
    17761 gcaggtttt
//
LOCUS       DAJVBX010000085        17734 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.085, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000085 DAJVBX010000000
VERSION     DAJVBX010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 17734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17734
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.085"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            287..11161
                     /locus_tag="OPV72_002446"
     CDS             287..11161
                     /locus_tag="OPV72_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BapA prefix-like domain-containing protein"
                     /protein_id="HCR9914721.1"
                     /translation="MRLLAVVSKLTGVSTTLESSAVTLNAPSIVKLSVARDEISQLTR
                     INQDLVVRLHSGETITIKNFYVTNDLGASQLVLAENDGTLWWVENPQAGLHFEQIADI
                     NELLVTSGASHEAGGAVWPWVLAGAVAAGGIAAIASSGGGDSHHHSDGDNPPPDNTNP
                     DGNPPDNSNPGGSNPNGNTPGSSNPVDTTPPLAPGELLISADGKTVSGEAEAGSLITI
                     KDPSGNVVGEGKADSDGKFSIDLTAPQISGEQLTVTATDDAGNTGPSATIDAPNIPLP
                     DTPVITAAIDDAAPLTGTLSNNQFTNDNTPTLEGTGSAGTVIHIYANGQEIGSTTVDT
                     SGNWHFAITSALADGENHFTAIATNVKGESSESARFTLTIDTLSPDAPRVELMADNTG
                     LLTGPLQNNDRTDEAKPLFSGQGEAGNTITIKEGSTVIGSATVDENGRWTFTPTTPLS
                     DGEHTFTVEQSDKAGNASRVTTTPTIIVDTTPPDAAIIDNVAKDGTTVSGTAEAGSTV
                     SIYDPAGNYLGSTITGENNHFSITLNPAQTHGERLEARIQDAVGNIGPATEFTASDSQ
                     YPAQPTILTVTDDAGAVTGLLKNGDATDDNRPTLSGTAEPGSTISINDNGFPVPSFPP
                     IVADADGKWSFTPSLALADGDHVFTATATNDRGTSGQSVAFTIDIDTQPPVLEGLAVS
                     DVGDRLTGTTEAGSTVVIKDSLGNTLGSGTAGDDGTFSIGISPAKINGETLSISVTDK
                     AANSGPVETLNAPDKTAPAAPNGLIVATDGLSVSGQAEAGATVTIRDSSNTVLGSAVA
                     NGNGQFIVPLNAAQTNGQALIATATDIANNESAAATVDAPDSTAPEMPKNVVISEDGA
                     SISGTAEPGSSITITTPDGTPLGSGKADGEGHFTLPLAPAQTNGEQVTVTATDSANNV
                     SPPTTAQAPDITAPDKPIITQVLDDVESFTGPLVNGQTTNDNRPTLSGTAEAGARVEI
                     FDNGVSLGLATLQPNGGWTFTPSQNLGEGAHRLTVIATDAKGNASPAGNESPESISFT
                     LRIDTQAPDAPQIVSAAITGGEGEVLLANGSITNQRMPTLSGTGEPGAIITLYNNGVE
                     LATVQVNPQGSWTYPLTRNLSEGLNILTATATDAAGNSSPTSGVFSVTLDTQPPAQPD
                     APLISDNVAPVIGNIGNNGATNDTTPTFSGTGEIGSTIILYNNGSEIGRTTVGDNGSW
                     NFTPAALTPETYTITVTETDIAGNISPPSASVTFTLDTTAPANPVITFAEDNVGEVQD
                     TIVSGATTDDNTPVIHGTGDIGSVITLYNGSSVVGVVTVDETGTWTLPVTSALPDGVY
                     TLTAIAADAAGNSSGVSNSFTFTVDTVPLQPPVVNEILDDVAPVTGPLTDGAFTNDRT
                     LTINGSGENGSTVTIYDNGVAIGTALVTDGVWTFNTSELSEASHALTFSATDDAGNTT
                     AQTQPITITVDITAPPAPTIQTVADDGTRVAGLADPYATVEIHHADGTLVGSAVANGT
                     GEFVVTLSPAQTDGGTLTAIAIDRAGNNGPATNFPASDSGLPAVPAITAIEDDVGSIQ
                     GNIAAGGATDDTMPTLRGTTDIGSTVEVFIDGDSAGFATVDASGNWIFEIATPLSEST
                     HYFTVQATNANGPGGLSAPVGITVDLSAPAQPVITSATDDVPGMTGTLDNGALTNDSR
                     PTLNGTGEAGATIRILDNGVEIGSATVDQSGNWRFTPNTPLESNAHIFTAVATDPAGN
                     SGQLSDGFTLNIDAQAPDVPVITSVIDDNNQPTVPVLPGQSTDDRQPILNGTGEPGAT
                     ITIFDNGTPLGTAQVGENGSWTFPVPRNLSEGSHNLTVSATDPAGNTSAVSAPWTIVV
                     DITPPAIPVLTSVVDDQPGITGNLVSGQLTNDATPTLNGRGEAGATINVYLDGNPASI
                     GTTTVNSDGTWSFTPQTPLANGSHTFTLSATDPAGNSSAVSSGFVLTIDTTPPAAPVI
                     ASVADNTAPVTGIVPNGGSTNETRPTLSGTGEAGTTISIYNGSALVGTAQVQANGSWS
                     FTPSTSLGAGVWNLTATATDAAGNTSAASEIRSFTIDTTAPAAPVIDTVYDGTGPITG
                     NLSSGQITDEARPVISGTREANTTIRLYDNGTLLAEIPADNSSSWRYTPDASLATGNH
                     VITVIAVDAAGNASPVSDSVNFVVDTTPPLTPVITSVSDDQAPGLGTIANGQNTNDPT
                     PTFSGTAEAGATITLYENGTVIGTTTAQPDGAWSVSTSTLASGTHVITAVATDAAGNS
                     SPNSTAFTLTVDTTAPQTPILTSVVDDVAGGVTGNLANGQITNDNRPTLNGTAEAGSV
                     VSIYDGDTLLGVTSANASGAWSFTPTTGLNDGTRTLTVTATDPAGNVSPATSGFTIVV
                     DTLAPTVPLITSIVDDVPNNTGAIGNGQSTNDTQPTLNGTAEANSAVSIFDNGALVAT
                     VNANASGNWSWTPTASLGQGSHAYSVSAADAAGNVSAASPSTTIIVDTIAPGAPGNLV
                     INATGNRVTGTAEAGSTVTITSETGVVLGTATADGTGSFTATLTPAQTNGQPLLAFAQ
                     DKAGNTGIAAGFTAPDTRVPEAPIITNVVDDVGIYTGAIANGPVTNDAQPTLNGTAQA
                     GATVSIYNNGALLGTTTANASGNWSFTPTGNLTEGSHAFTATATNANGTGSVSTAATV
                     IVDTLAPGTPSGTLSADGGSLSGQAEANSTVTVTLAGGVTLTTTAGSNGAWSLTLPTK
                     QIEGQLINVTATDAAGNASGTLGITAPILPLAARDNITSLDLTSTAVTSTQNYSDYGL
                     LLVGALGNVASVLGNDTAQVEFTIAEGGTGDVTIDAAATGIVLSLLSTQEIVVQRYDT
                     SLGTWTTIVNTAVGDFANLLTLTGSGVTLNLNGLGEGQYRVLTYNTSLLATGSYTSLD
                     VDVHQTSAGIISGPTISTGNVMADDTAPTGTTVTAITNANGVSTPVGAGGVDILGQYG
                     TLHINQDGSYTYTLTKPTAGYGHKESFTYTITQNGVGSSAAQLVINLGPAPVPGSVIA
                     TDNNASLVFDTHVSYVNNGPSTQSGVTVLSVGLGNVLNANLLDDMTNPIIFNVEEGAT
                     RTMTLQGTVGGVSLVSTFDLYVYRFNDAIQQYEQFRVQKGWINTLLLAGQSQPLTLTL
                     PGGEYLFVLNTASGISVLTGYTLAISQDHTYAVDSITANTTGNVLTNDVAPTDALLTE
                     VNGVAIAATGTTEVNGLYGSLIIDARGNYTYTLKNGVGADSIKTPDSFIYTLKAPNGD
                     TDTASLNITPTARALDAINDVSDTLSVATLQDTAAWLDSSVGSASWGLLGKSGSGSGT
                     FDVATGTVLKGASLVFDVSTLITLGNLNISWAIQENGTVIRNGTVPVANITLGSATVT
                     VNLSGLELDAGTYTLNFTGTNTLAGAATITPRVIGTTVDLDNFETSGTHTVLGNIFDG
                     SDAAGAMVQLNTVNTRLSISGYNGSAATLDAAANTTSATIQGHYGTLQINLDGAYTYT
                     LNNGVAMSSITSKEVFTYQLDDKIGHTDSATLTIDMAPQIVSTNQNDVLIGSAYGDTL
                     IYHLLNGADATGGNGADRWQNFSTAQGDKIDIHELLTGWDHQAATLGNFVQVHTSGAN
                     TVISVDRDGAGSAFKSTDLVTLENVQLTLNDLLQNNHLITGG"
     gene            11225..12634
                     /locus_tag="OPV72_002447"
     CDS             11225..12634
                     /locus_tag="OPV72_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family outer membrane protein"
                     /protein_id="HCR9914722.1"
                     /translation="MGRVAPVAIVLAFALFHHQPRGAEALPMITSEGLATDQMLPSLD
                     GSAAELPLSAAAPGNLTLNDAVNRAVNWHPSIREAVGKLLAQNEQIEVAKSKYYPQVS
                     AGVNNGYSNTYTDHGYSPSLVLSVSQMLYDFGKVASQVRAETAGAAQQQANVLLSIDT
                     VAHETANAIVQTQSWQQMVEAAEEQLVALDSIGKLIRQRSDEGATSLSDVVQTEARIE
                     SARSQLAQYQANLDSAKASLMSWLGWNSLNGINNDFPAKLARSCETATPEDRLVPAVL
                     AAWAQANVARANLDYASAQMTPTISLEPSVQHYLNDKYPSHEVLDKTQYSTWVKVEMP
                     LYQGGGLTARRNAASHAVDAAQSTIQRTRLDVRQKLMEARSQAMSLASALQILRRQQQ
                     LSERTRELYQQQYLDLGSRPLLDVLNAEQEVYQARFAELQTESQLHQLQLNYLYNTGA
                     LRQAFALNHRSIQSVEIQP"
     gene            12631..14787
                     /locus_tag="OPV72_002448"
     CDS             12631..14787
                     /locus_tag="OPV72_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I secretion system permease/ATPase"
                     /protein_id="HCR9914723.1"
                     /translation="MTRAAPDVEEVLSERALSQWAQAISHVAGHYRVACSPGSIQANA
                     PWFRGKSRTTALTQLARQAGLSFHAPDIDKTAFSQWRLPLVVELRDGQLLVIEHVNGE
                     DAVDVFVIEEEGQRNRLTLSELLPEILYVAALRPLSALKDSRVDRYISRFKPDWMREL
                     VLQDIRPYLPVMVAAFLINVLSLAGIVFSMQVYDRVIPAQSYPTLYVLSFGVLVAVLF
                     GFLLREARTHIMDVLGKRADMRISDRVFGHALRLRNSAIPRSTGSFISQLRELEQIRE
                     MITSSTLATIVDLPFFFLFMIVLAIIAPPLAWIAPVAALLMILPGVALQKKLAVLANQ
                     AAHEATLRNAVLVESVQGLEDIKLMQAENRFLQQWNSYIRITGESGLRTRKLTQRLIS
                     WGMSVQSLVYAAVIMFGAPMVIEGSMTTGAVVAASMLGSRMIAPMANLCGVLARWQQV
                     KAAKMGLDNIMQLPTETQHDDSLIHRDILHGHYLFENAQFRYHNDDQRIPLRLVRLEI
                     MPGERIAILGRNGAGKSTLLQAMAGGLEMIQGDARLDNLSLSHIDMADLRRNIGFLSQ
                     NARLFFGTLRENLTLGAPHANDEQIFDALEVSGGAVFVRRLAKGLDHPIMEGGNGLSG
                     GQRQSLLLARMLLRSPNIVLLDEPSASLDEHTEREFIQRLHQWLGNRTLVVATHRVPI
                     LELVERVVVLKEGQLVMDAPKAQALNADRMQSHRRE"
     gene            14819..15982
                     /locus_tag="OPV72_002449"
     CDS             14819..15982
                     /locus_tag="OPV72_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family type I secretion periplasmic adaptor
                     subunit"
                     /protein_id="HCR9914724.1"
                     /translation="MDDFDIQRERAFSGAGRIVLICSLLFLILGIWAWFGRLDEVSTG
                     NGKVIPSSREQVLQSLDGGILAQLTVREGDRVQANQIVAQLDPTRLASNVGESAAKYR
                     ASLASSARLTAEVSDLPLAFPAELNGWPDLIAAETRLYKSRRAQLADTEAELRDALAS
                     VNKELTITQRLEKSGAASHVEVLRLQRQKSDLGLKITDLRSQYYVQAREALSKANAEV
                     DMLSAILKGREDSVTRLTIRSPVRGIVKNIQVTTIGGVIPPNGEMMEIVPVDDRLLIE
                     TRLSPRDIAFIHPGQRALVKITAYDYAIYGGLDGVVETISPDTIQDKVKPEIFYYRVF
                     IRTHQDYLQNKSGRRFSIVPGMIATVDIKTGEKTIVDYLIKPFNRAKEALRER"
     gene            16054..16416
                     /gene="ssrA"
                     /locus_tag="OPV72_002450"
     tmRNA           16054..16416
                     /gene="ssrA"
                     /locus_tag="OPV72_002450"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(16525..17298)
                     /locus_tag="OPV72_002451"
     CDS             complement(16525..17298)
                     /locus_tag="OPV72_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001759369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="reverse transcriptase"
                     /protein_id="HCR9914725.1"
                     /translation="MTIEVQRWEDKFEIKPGVWVYVPSVEARKVGGKILQAVRNKWIP
                     PLYFYHLRTGGHLKAARLHLKSDFFAVVDIKQFFQSTSRSRITRDLKSYFTYSQAREI
                     STFSTVRNLSHSPHKHVLPFGFVQSPILATLCLDKSYFGSLLRRLNKHHDLKLSVFMD
                     DVIISSNNLAQLQAAYDEALVAMRKSGYQANMSKTQAPSSKISVFNLTLSKGVMKVTS
                     QKMSDFLIDFYSSNYEPHRIGVKNYVEAVNPGQAKLFKL"
     gene            complement(17267..17440)
                     /locus_tag="OPV72_002452"
     CDS             complement(17267..17440)
                     /locus_tag="OPV72_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001384722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914726.1"
                     /translation="MDTNELGLVKARVELITAMLKCATAFVGLVGAVYAVLNMAFNYN
                     NLTHDNRSSKVGR"
BASE COUNT         4218 a         5166 c         4780 g         3570 t
ORIGIN      
        1 acacaaactc cgttatattt cagacgcact aacaccttta tcaatagatc ttaatttgca
       61 gaaagatttt tttctgacta tatcatctaa tacgaaagca ctagtcaggc acaaaaaaca
      121 aatggttatt cgacgagaaa accagacctt cacctacgct cataaaaaag aatatggcta
      181 cggaaattca tctctcacga taaacgggaa ggctcgtcta cgcattttgc cctgaacgtc
      241 gtgcccgtta attaatacac agagcaaatc catcaggagc taatttatgc gtctactcgc
      301 cgtggtttcg aaattgactg gcgtctccac cactctggaa tcctcagcgg tcactcttaa
      361 cgcgccttca attgttaaat tatcagtggc ccgggatgaa attagtcaac ttacgcgcat
      421 taatcaggat ctggtggtga ggctccattc cggcgaaacg atcacgatta aaaactttta
      481 cgttaccaac gatctgggcg caagccagct ggtactggcg gaaaacgatg gcacgttatg
      541 gtgggtggaa aatccgcaag ccgggctaca ttttgaacaa atcgctgata ttaatgagct
      601 gctggtcact tccggcgctt cccatgaagc aggcggcgcc gtttggccgt gggtactggc
      661 tggcgcggtg gcggctggcg gcattgccgc tatcgcgtct tccggcggcg gcgattccca
      721 ccatcattcg gatggcgata atccgccccc cgataacacc aatcctgacg gtaatccccc
      781 tgataacagc aatcccggcg gcagtaaccc taacggcaat actccaggta gcagtaatcc
      841 tgtagatact accccgcctc tcgctcccgg cgaattattg atttcagcgg acggaaaaac
      901 ggtgagcggc gaggccgaag cgggcagtct cattaccatc aaagatccct caggcaacgt
      961 cgttggcgag ggcaaagcgg atagcgacgg taaatttagt attgatctga cagcgccaca
     1021 gattagcggc gaacaactta ccgtgactgc gactgacgat gccggcaata ccggcccatc
     1081 cgcaaccatt gatgcgccca acattcctct ccccgataca ccggttatca ccgccgctat
     1141 cgatgatgcc gctcccctca ccggcacgct gagcaataat cagtttacga acgacaatac
     1201 ccccactctg gagggcaccg gcagcgcagg cacagtcatc catatttacg ccaatggtca
     1261 ggaaataggc tcaacaacag ttgataccag cggaaactgg cattttgcca ttaccagcgc
     1321 gctagcggat ggggaaaatc atttcaccgc cattgcgact aacgttaaag gcgaaagtag
     1381 cgaatcagcc cgctttacgc tgactatcga cacactcagc cccgatgctc cacgcgttga
     1441 actgatggcc gataacaccg gtttgctcac cggaccgcta cagaataatg accggactga
     1501 cgaggcaaaa ccgctatttt ccgggcaggg agaggcaggc aataccatca cgattaaaga
     1561 gggttcaacc gttatcggca gcgctaccgt agacgaaaat ggacgctgga cctttacgcc
     1621 gactacgccg ttaagcgatg gcgaacatac ctttaccgtc gaacagagcg acaaagccgg
     1681 aaacgcaagc cgcgtgacga caacgcctac tatcattgtg gacaccacgc cgccggacgc
     1741 cgctatcatt gataatgtcg cgaaagacgg cacaaccgtt agcggcaccg ctgaagctgg
     1801 cagtaccgtg tcgatctatg acccggcggg aaattacctg ggctccacga ttaccggaga
     1861 aaataaccac ttcagcatca cgctgaatcc ggcccagacc cacggcgagc gtctggaagc
     1921 gcgtattcag gacgccgtcg gtaacatcgg ccccgccaca gagtttaccg cttctgactc
     1981 acagtatcct gcccagccga ctatccttac cgtgacggat gacgctggcg ccgttaccgg
     2041 gctgttgaaa aatggcgatg ccacagatga taaccgccca accctcagcg gtactgctga
     2101 accaggcagt acgatatcga ttaacgataa tggctttcct gttccgagct ttccgcccat
     2161 tgtcgctgac gctgacggca aatggagctt taccccctcg ctggcgcttg ccgatggcga
     2221 ccatgtcttt accgctaccg cgaccaacga tcgcggcact agcgggcagt ccgtcgcctt
     2281 taccattgat atcgacacgc agccgccggt gctggaaggc ctggcagtta gcgacgtcgg
     2341 cgacagactc accggcacta cggaagctgg cagcactgtg gttatcaaag atagcctggg
     2401 aaatacgctc gggagtggaa cggcaggcga cgacggcacc ttctcaatag gtattagccc
     2461 ggcgaaaatt aacggtgaaa cattaagcat tagcgttacc gataaagccg cgaatagcgg
     2521 tccggtagaa acgctgaacg cgccggataa aactgcgcct gcggcaccga acggtcttat
     2581 cgtggcgacc gacggtctgt ccgtaagcgg tcaggcggaa gccggggcaa cggtcactat
     2641 ccgcgacagt agcaataccg tacttggcag cgccgtcgct aacggcaacg gacaatttat
     2701 cgttccgctg aatgcggcgc agactaacgg ccaggcgctt atcgctaccg ccaccgatat
     2761 agcgaacaac gaaagcgccg ccgcgacggt cgacgcgccg gacagtaccg cgccagaaat
     2821 gccgaaaaac gtggtaatta gtgaggatgg cgccagtatc agcggcaccg ccgaaccggg
     2881 tagctccatt acgatcacca cgccggacgg cacgccgctc ggcagcggca aagcagatgg
     2941 cgaaggtcat tttacccttc ccctcgcccc cgcacagacc aacggcgaac aggttaccgt
     3001 caccgccacc gacagcgcca acaacgtcag cccgccaact acagcgcaag cgcccgatat
     3061 caccgccccg gataagccca ttatcaccca ggtgctggac gatgttgaaa gcttcaccgg
     3121 gccgctggtt aacggacaaa ccaccaatga caaccgcccc acccttagcg gtacggcgga
     3181 ggctggcgcg cgtgtcgaaa tttttgataa cggcgtttcg ctggggctcg ccacgctaca
     3241 gcccaacggc ggctggacgt ttacgccgtc gcaaaattta ggtgaaggcg cgcatcgact
     3301 gaccgtaatc gcaaccgacg ctaaaggcaa tgccagtccg gcggggaacg aaagtccgga
     3361 atccatcagc tttaccctac gcatcgatac ccaggcgccg gatgcgccgc agatcgtgtc
     3421 agccgccatc acaggcggag aaggcgaggt gctactggca aacggcagta ttaccaatca
     3481 gcgtatgccg accctcagcg gcaccggcga acccggcgcc atcatcaccc tgtacaataa
     3541 cggcgtagaa ctggctaccg tccaggtcaa tccacagggt agctggacct atccgctaac
     3601 ccgtaatctg agcgaagggt taaacatcct gacggccacc gccacggatg ccgcaggcaa
     3661 tagtagcccg acctccggcg ttttctccgt tacccttgat acccagcctc cagcgcagcc
     3721 tgacgcgccg ctaatcagcg ataacgtcgc gccggttatc ggcaacatcg gcaataatgg
     3781 cgcaacgaac gataccacgc cgaccttcag cggcacggga gagatcggca gcacgataat
     3841 tctctacaat aatggcagtg aaattggtcg cacaacggta ggcgataacg gtagctggaa
     3901 ctttacgcct gcggcactga cgccagaaac ctataccatt accgtcacgg aaaccgatat
     3961 agcgggcaat atcagtccac cttccgcctc agtcactttt acgctagaca ccactgcgcc
     4021 cgccaatccg gttatcactt ttgccgaaga taacgtcggc gaagtccagg atactattgt
     4081 cagcggcgca accactgacg acaatacacc ggtcattcac ggcactggcg acatcggcag
     4141 cgtgatcacg ctctataatg gcagtagtgt cgtgggcgta gtcaccgtcg atgagaccgg
     4201 tacctggacg ctgccggtga ccagcgcgtt gccggatggc gtctacaccc tgaccgccat
     4261 tgccgccgat gccgccggaa acagcagcgg cgtatcgaac agctttacct tcaccgtcga
     4321 caccgttccg ttgcagccgc ccgtcgtcaa tgagatcctc gacgatgttg caccagtgac
     4381 cgggccatta accgatggcg cctttactaa cgatcggacg ctgactatta acggcagcgg
     4441 cgaaaacggc agcaccgtca cgatttacga caatggcgtg gcaatcggga cggcgctcgt
     4501 taccgacggg gtctggacat tcaatacgtc cgaattgtca gaagccagcc atgcgctaac
     4561 cttcagcgcg actgacgatg ctggaaatac cacggcgcaa acccaaccga tcaccattac
     4621 cgtggatatc accgccccgc ccgcgccaac gatccagacg gtggccgatg atggcacgcg
     4681 cgtcgccgga cttgccgatc cttacgctac cgttgaaatt catcatgccg atggcaccct
     4741 ggtcggcagc gctgtcgcta atggcaccgg tgaatttgtc gtcacgctca gtccggcgca
     4801 aaccgatggc ggtacgctga cggcaattgc tatcgatcgc gcggggaata acggcccggc
     4861 tacgaatttt cctgcttccg acagcggtct gcccgccgtc ccggccatca cggcgattga
     4921 agatgatgtc gggagcatac aggggaatat tgcagcgggc ggcgccacgg acgacaccat
     4981 gccgacgctg cgcggcacca cggatatcgg ctctaccgtt gaagttttca ttgatggcga
     5041 ttcggcaggc tttgccaccg ttgacgccag cgggaactgg atctttgaga tcgcgacgcc
     5101 attaagcgaa agcacacatt acttcaccgt ccaggcaacc aatgcgaatg gcccgggcgg
     5161 cctgtccgca ccggtcggga tcactgtcga tcttagcgcg ccggcacaac cggttattac
     5221 cagcgcaacg gatgatgtcc ccggcatgac cggtacgctg gataacggcg cgctcaccaa
     5281 tgattcacgc ccgacgctca acggaacggg agaagcaggc gccacaatcc gcattctgga
     5341 taacggcgta gaaatcggtt ccgctacggt agatcaaagc ggcaactggc gcttcacccc
     5401 gaacacgccg ctggagagca acgcacacat ctttaccgcc gtggcgaccg atcccgccgg
     5461 caatagcggt cagctttcgg atggttttac gctgaacatt gacgcgcagg caccagatgt
     5521 gccggttatc acctccgtga ttgacgataa caatcaaccg accgtcccgg tgttaccggg
     5581 gcaatccacc gacgatcggc agccaatact gaacggaact ggcgaacctg gcgcgacaat
     5641 caccattttt gataacggta cgccgcttgg cacggctcag gtaggcgaaa acggtagctg
     5701 gaccttcccg gtgccccgca atttgtcaga gggaagccat aatctgacgg ttagcgctac
     5761 cgatccggcg ggcaatacca gcgcggtctc cgcgccgtgg acgatcgtgg tcgatattac
     5821 gcctccggcg atcccggttc tcacctccgt tgtggatgac cagcccggta ttaccggcaa
     5881 cctggttagc gggcagctaa cgaacgatgc gacgcccacc ctgaacgggc gcggagaggc
     5941 aggcgcgacg attaatgtct atcttgacgg taatcccgcg tccatcggta ccacgacggt
     6001 gaatagcgac ggcacgtgga gtttcacgcc gcagacgccg cttgcaaacg gtagccacac
     6061 gttcaccctt agcgccaccg atccggcggg taatagcagc gcggtgtcca gcggatttgt
     6121 gctgacgatt gacaccacac cgcccgccgc gccggttatc gccagcgtgg cagataatac
     6181 ggcgccggta acgggcatcg tccccaacgg cggctcgacg aacgaaaccc gaccaacact
     6241 ctcgggtacc ggtgaggcgg gtacaaccat ctcgatttat aatggcagcg cgctggtcgg
     6301 cacggcgcaa gttcaggcca acggtagctg gagctttaca ccgtctacct cgctgggcgc
     6361 gggcgtctgg aacctgacgg cgacagcaac cgatgcggca ggcaatacca gcgccgcgtc
     6421 cgaaatacgc tcgtttacta ttgataccac ggctcccgcc gcgcctgtta ttgatacggt
     6481 ctacgacggt acgggcccca ttaccggcaa tctgagttca gggcagatca cagacgaggc
     6541 gcgccctgtc attagcggca cccgtgaagc caacacaact attcgtctct acgataacgg
     6601 cacgctgctg gctgaaattc ccgccgacaa tagcagtagc tggcgctaca cgcccgacgc
     6661 ctcgctggcg acgggcaacc atgtaattac cgtcattgcc gttgatgccg caggcaacgc
     6721 cagccccgtt tcggacagcg ttaatttcgt cgtcgatacc acgccgccgc tgacgccggt
     6781 aatcacatca gtcagtgacg atcaggcgcc aggcctcggc acgatcgcga acggccaaaa
     6841 taccaacgat cctacgccaa ccttcagcgg caccgcagaa gccggcgcca cgatcacgct
     6901 ctatgaaaat ggtacggtca ttggcacgac aacggctcag cctgacggcg cgtggagcgt
     6961 ctccacctca acgttggcaa gcggaacgca cgtcatcacc gccgtcgcca ccgatgccgc
     7021 aggaaacagc agcccgaaca gtacggcttt caccctgacg gtcgatacca ccgcgccgca
     7081 aacgccaatc ctgacgtccg tggtggatga cgtcgcgggc ggggtcacag gaaatctcgc
     7141 taatggtcag ataaccaatg ataaccgccc cacgctgaac ggcactgccg aagcgggcag
     7201 cgtggtcagt atctatgatg gcgacactct gcttggcgtc acctcggcta acgctagcgg
     7261 cgcatggagc ttcacgccga cgacagggtt aaacgacggc acgcgcacat taacagtgac
     7321 cgccaccgac ccagcaggca acgttagccc ggccaccagc ggttttacta tcgtggtcga
     7381 tacccttgcg ccaacggttc cgcttataac cagcatcgtt gatgatgtcc cgaacaatac
     7441 cggcgccatt ggcaatggac aatcgaccaa tgacacacag ccgacgctca acggtaccgc
     7501 ggaagccaac agcgcggtaa gtatcttcga taatggcgcg ctggtcgcga ccgtgaacgc
     7561 caatgccagc ggcaactgga gctggacgcc aaccgcctcg ctcggccagg gaagtcatgc
     7621 ctatagcgtt agcgccgccg atgcggctgg caacgttagc gccgcttcgc catcgacaac
     7681 gattatcgtg gataccattg cgcccggcgc gcccggtaac ctagtcatca atgctaccgg
     7741 taatcgggtg acgggcaccg cggaagcagg cagcacagtg acgattacct ctgagactgg
     7801 tgtggtactg ggaaccgcca ccgccgacgg tacgggcagc ttcaccgcca cactcacgcc
     7861 cgcgcagacc aatggtcagc cgctactggc atttgcccag gataaagcag gcaacactgg
     7921 cattgccgcc ggatttaccg cgcccgatac gcgcgtgccg gaagcgccga tcatcaccaa
     7981 cgtagtggat gatgtgggta tttataccgg cgctatcgcc aacggtccgg tcactaatga
     8041 cgcacaaccc acattgaatg gtaccgctca ggcgggcgcc acggtgagca tttataacaa
     8101 cggggcgctg ctcggcacca ccacggcgaa cgccagcggg aactggagct ttaccccgac
     8161 aggcaatttg accgaaggca gccacgcctt caccgctacc gcaactaacg ccaacggtac
     8221 aggcagcgtc tccaccgccg cgacggtgat tgtcgatacg ctggcgcccg gtacgccgtc
     8281 aggtacgctc agcgccgatg gcggttcact ttccggacag gctgaggcaa acagcaccgt
     8341 aaccgtaacg ctggcggggg gcgtgacgct caccaccacc gccggcagca acggcgcatg
     8401 gtctctcacc ttgccgacaa aacaaattga aggtcaactc attaacgtga cggccactga
     8461 cgctgcgggt aacgcctccg gcacgttagg cattaccgcg ccgattctgc cgctggcggc
     8521 aagggataac ataaccagtc ttgatctgac ctctaccgcc gtcaccagca cgcaaaacta
     8581 ttcggattac ggcctgctgc tggttggcgc gcttggcaat gtcgcctcgg ttttgggtaa
     8641 cgataccgct caggttgagt tcaccattgc tgaaggtggt acgggcgacg tcaccatcga
     8701 tgccgccgca acgggaatcg tgctttcgct gctcagcact caggagatag tggtacagcg
     8761 ctatgacacc agcctcggca cctggacgac gatcgtcaac accgccgttg gcgacttcgc
     8821 gaatttgctt accctgaccg ggagcggcgt taccctgaac ctgaacggac tgggcgaagg
     8881 ccagtaccgg gtactcactt ataacaccag tctgctcgcc accgggtcat ataccagcct
     8941 ggatgtcgat gtacaccaga ccagcgcagg tattattagc gggccaacca tcagtaccgg
     9001 caacgtcatg gctgatgata ccgcgccgac gggcaccacg gtcaccgcca tcaccaacgc
     9061 caacggcgtc agtacgccgg tcggcgcggg cggcgtggat atcctggggc aatacggcac
     9121 gctgcacatt aatcaggatg gcagttacac ctacacgctg actaagccca cggcgggata
     9181 cggacataaa gagagcttca cctacaccat cacccagaat ggcgtcggta gcagcgccgc
     9241 gcaactggtt attaatttgg gtcccgcgcc tgtaccgggc agcgtgatag cgacagacaa
     9301 taacgcctcg ctggtctttg atactcacgt tagctacgtc aacaacggcc cctcgacaca
     9361 aagcggcgtc acggtattaa gcgtcggact tggtaatgta ctgaacgcga atctgcttga
     9421 tgatatgact aatccgatca tctttaacgt tgaagaaggc gctacgcgaa ccatgacgtt
     9481 acagggaacc gtcggcggcg tctcactggt ttccacgttc gatctgtacg tttatcgctt
     9541 caacgatgcc attcaacaat atgagcagtt ccgggtgcaa aagggctgga ttaacaccct
     9601 gctgttagcc ggacagtccc agccgctgac cctgacgttg cctggcggcg aatacttgtt
     9661 cgtgctgaat accgccagcg gcattagcgt cctcactggc tatacgttgg cgatttccca
     9721 ggaccacacc tatgccgttg acagtatcac cgccaacacc accggcaacg tactgaccaa
     9781 tgatgtcgcc cctacggacg ccctcctcac tgaagtaaac ggcgtggcga ttgcggcgac
     9841 cggcacgacg gaggtaaatg ggctgtatgg ctcgctcatc attgacgcaa gaggcaacta
     9901 tacctacacg ctgaagaacg gcgtcggcgc cgacagcatt aaaacgccgg acagctttat
     9961 ctatacgctc aaagcgccaa acggcgatac cgatacggcc tcgctcaata tcacgccaac
    10021 cgccagggcg ctggatgcga ttaatgatgt cagcgatacc cttagcgtcg ccacgcttca
    10081 ggataccgct gcctggctgg actccagcgt cggcagcgcc agttgggggc tactcggcaa
    10141 atcgggcagc gggagcggca cctttgacgt tgcaacgggc accgtactta aaggcgcgtc
    10201 actggtcttt gatgtctcca cgctcattac gctgggcaat ctgaatatta gctgggccat
    10261 tcaggagaac ggaaccgtca tacgcaacgg aaccgtcccg gtggcgaata tcacgctggg
    10321 cagcgcgacg gtgaccgtca acctgagcgg cctggagctg gatgccggaa cgtacacgct
    10381 taactttacc ggcaccaata ccctggccgg ggcggcgaca atcacgccac gcgtcatcgg
    10441 caccaccgtc gatctggata attttgaaac gtccggaacg cataccgttc tcggcaatat
    10501 ttttgacggc agcgacgcgg cgggggcgat ggttcagctt aatacggtga atactcgcct
    10561 gagcattagc gggtataacg gcagcgccgc cacgctggac gccgcggcga ataccaccag
    10621 cgccacgatt cagggacatt acggcacatt gcaaattaac ctcgatggcg cttacaccta
    10681 caccctgaat aatggcgtcg cgatgtcgtc catcaccagt aaagaggtct ttacctatca
    10741 actggatgac aagataggtc atacggatag cgccacattg accattgata tggcgccgca
    10801 aatcgtcagt accaaccaaa acgatgttct tatcggctcc gcctatggcg atacgctgat
    10861 ttatcacctg ttaaacggcg cggacgcgac cggcggcaac ggcgccgatc gctggcaaaa
    10921 cttctccacc gcgcagggcg acaagatcga tatccacgaa ctgctgaccg gctgggatca
    10981 ccaggcggcg acgctaggta actttgttca ggttcatacc agcggcgcca atacggtgat
    11041 atccgtcgat cgcgacggcg ccggcagcgc gtttaaatca actgaccttg tcactttgga
    11101 gaatgtgcag ctcacgctaa atgatctgtt gcagaacaac cacctgataa ccggcggttg
    11161 ataaaaagcc ccgaacgcca cgacgttcgg ggcaacaagc ggtgatattt aaaagggata
    11221 aactatggga agagtcgcgc ctgtcgccat cgtactggca tttgctttgt ttcatcacca
    11281 gccccggggc gcagaagcgc tgccaatgat tacatccgaa ggattagcaa cggaccagat
    11341 gcttccttcg ctggatggct ccgccgctga gttgccgctc agcgccgccg cgccgggcaa
    11401 cctgacgctc aatgacgcgg tcaatcgcgc cgttaactgg catccttcta ttcgcgaagc
    11461 cgtcggcaaa ctgctcgcac agaatgaaca aatagaggtc gccaaatcga aatattatcc
    11521 gcaagtcagc gctggcgtga acaatgggta cagcaatacc tacaccgatc acgggtatag
    11581 cccctcgctg gtgctgtcgg tatcgcaaat gctttatgac ttcggcaaag tggcaagcca
    11641 ggttcgcgcc gaaaccgcag gcgcagcaca gcaacaggcc aacgtgttgc tcagtattga
    11701 taccgtcgcg cacgaaaccg ccaacgccat tgtacaaacg cagagctggc agcaaatggt
    11761 agaagcggcg gaagaacagc tcgtcgcgct ggacagcatc ggtaaactta tccggcagcg
    11821 cagcgatgaa ggcgctacgt cgctatctga cgtggtgcaa accgaagcca gaatcgaatc
    11881 cgcccgctcg caactggcgc agtatcaggc caatctcgac agtgcgaaag cctcactgat
    11941 gagctggctg ggctggaatt cgcttaacgg catcaataat gacttcccgg cgaaactcgc
    12001 tcgcagctgt gagacagcga cgcccgaaga tcggctggtg cccgcggtac tggccgcctg
    12061 ggcgcaggcc aacgttgcgc gggcgaatct ggactatgcc agtgcgcaaa tgacgccgac
    12121 gatttcgctc gaaccttctg tacaacatta tcttaatgac aaatatccca gtcatgaagt
    12181 gctggataaa acccagtatt ccacctgggt gaaagttgag atgccgcttt atcagggcgg
    12241 agggctgact gcccgacgca acgccgccag ccatgcggta gacgcggctc agtcgaccat
    12301 tcagcgcacc cggcttgatg tccgccagaa actgatggag gcgcgcagcc aggcaatgag
    12361 tcttgccagc gcgttacaaa tccttcgtcg gcaacagcag cttagcgaac gcacgcgcga
    12421 actgtatcag cagcaatacc ttgacctcgg ttcccgcccg ttgctcgacg tgcttaatgc
    12481 ggagcaggag gtttaccagg cgcgttttgc cgaactgcaa acggaaagcc agttgcatca
    12541 gttacaactg aactatctgt ataacaccgg cgcgcttcgt caggcgttcg cgttaaatca
    12601 tcgcagcatt caatccgtgg agatccagcc atgacccgcg ccgcccccga tgtagaagag
    12661 gtactcagtg agcgcgcgct aagccaatgg gcgcaggcca tcagccatgt cgccggtcat
    12721 tatcgcgttg cctgttctcc cggttcaatt caggccaacg ccccgtggtt taggggtaaa
    12781 agcagaacga ccgccttaac gcagctcgcg cggcaggcgg gtttatcctt tcatgcgccg
    12841 gacatagaca aaacggcatt tagtcagtgg cgattgccgt tggttgtcga gctccgggac
    12901 gggcagttat tggtcatcga acatgttaat ggcgaagatg cggtagacgt ttttgtgatt
    12961 gaagaagagg gtcagcgtaa ccgcctgacg ctcagcgagt tattgccgga gatcctctat
    13021 gttgccgcgc tacgcccgct atcggcgctc aaggatagcc gcgtcgaccg ctatatctcc
    13081 cgctttaaac ccgactggat gcgcgagctg gttctgcagg atattcgccc ttatttaccg
    13141 gtaatggtcg ccgcctttct gattaacgtg ctgtctctgg ccgggattgt gttctctatg
    13201 caggtttacg atcgggtgat ccccgctcag tcatatccta ccctgtacgt gctctccttc
    13261 ggcgtgctgg tagcggtgct gttcggtttt ctgctgcgtg aagcgcgtac gcacattatg
    13321 gacgtgctcg gtaaacgcgc cgatatgcgc atttccgatc gggtattcgg tcatgcgtta
    13381 aggctgcgca acagcgctat cccccgttcc accggcagtt ttatctcgca gttacgtgaa
    13441 ctggagcaga tccgcgagat gattacctct tcaacgctgg cgaccattgt cgatctgcct
    13501 ttctttttcc tgtttatgat agtcttggcg attattgccc caccgctggc atggatagcg
    13561 cccgtggcgg ctctgctgat gatcctgccg ggcgtcgcac tgcaaaaaaa actggctgtc
    13621 ctcgccaacc aggccgccca cgaagcgacg ctacgcaatg cggtcttggt cgaaagcgtt
    13681 caggggctgg aagatattaa actgatgcag gcggagaacc gctttcttca gcagtggaat
    13741 agctatatcc gtattaccgg cgagtcgggt ctacgcaccc gcaaactcac gcaaaggctt
    13801 atcagttggg ggatgtcggt acaaagtctg gtgtatgccg cagtgattat gttcggcgcg
    13861 ccgatggtca ttgaaggcag tatgactacc ggcgccgtgg tcgccgcgtc gatgctcggc
    13921 tcacggatga tcgcgccaat ggctaacctg tgcggcgtgc tggcgcgctg gcagcaggtg
    13981 aaagcggcga agatgggtct cgacaacatt atgcaactgc ccactgagac acagcatgac
    14041 gatagcctga tacaccgcga catcctccac gggcattacc tctttgaaaa cgctcagttt
    14101 cgttaccata acgacgatca acgcataccg ctgcgcctcg tgcgtctgga gatcatgcca
    14161 ggcgagcgga ttgcgatact ggggcgtaac ggtgcgggta aatccacact tttacaggcg
    14221 atggcgggcg gcctggagat gattcaggga gatgcccggc ttgataatct cagcttgtcg
    14281 cacatcgata tggcggattt acgccgcaac atcggctttc ttagccagaa cgcgcggctt
    14341 ttcttcggca ccctacgaga gaacctgacg ctcggcgcgc cgcacgccaa cgatgaacag
    14401 atttttgacg cgctcgaagt cagcggcggc gccgtcttcg tcaggcggct ggcaaaaggg
    14461 ttggatcatc ccattatgga gggtggtaac ggcctgtccg gcgggcagcg tcagtccctg
    14521 ttgctggcga gaatgctgct gcgctccccc aatattgtgc tacttgacga acccagcgcc
    14581 tcgctggacg agcatacgga acgagagttt attcagcggt tacatcagtg gcttggcaac
    14641 cgtaccctgg tcgtcgcaac gcaccgggta ccaatactgg agctggttga gcgtgtcgtt
    14701 gtcctgaaag aaggacaact ggtgatggac gcgccaaaag cgcaggcgct taacgcggat
    14761 cggatgcaaa gtcaccgtcg ggagtagaaa aatgaaaatc aatcagcatg atgccgcgat
    14821 ggacgatttc gatattcagc gtgaacgggc gttttccggc gcgggtcgta ttgttctgat
    14881 ctgctcactg ttatttctca ttctcggcat ctgggcgtgg tttggccgac tggatgaggt
    14941 ttccaccggc aacgggaaag taatccccag ttcacgcgaa caggttctgc agtcgctgga
    15001 tggcggcatt ctggcgcagt tgacggtgcg ggaaggcgac agagttcagg ctaaccagat
    15061 tgtcgcccag cttgatccga cgcgtctggc gtccaatgtt ggtgaaagtg cggcaaaata
    15121 tcgcgcttca ctcgcctcca gcgcacggtt aaccgcggaa gtcagcgact tacctctcgc
    15181 cttccccgct gagctgaacg gctggccgga tctgattgcc gcagagacgc gtctctataa
    15241 aagccgccgc gcgcagctgg ccgataccga agccgagcta cgggatgcgc tggcgtcggt
    15301 taataaagag ctgaccatta cccagcggct ggagaaaagc ggcgcggcca gtcatgttga
    15361 agtgctacgc ctgcaacgac aaaaaagcga tttaggctta aaaattaccg atctgcgctc
    15421 acaatattat gtgcaggcac gcgaagcgtt atcaaaagcg aacgctgagg tcgatatgct
    15481 ctccgccatt ttaaaaggac gcgaggattc cgtcacccgc cttaccatac gttcgccggt
    15541 acgcggcatt gttaaaaata tccaggtcac gacgattggc ggcgtgatcc cgcctaacgg
    15601 tgagatgatg gagatagtgc cggtagacga tcgtctgttg attgaaaccc gcctttcgcc
    15661 gcgtgatatc gcctttattc atcccggcca acgcgcattg gttaaaatta ctgcttacga
    15721 ttacgccatt tacggcgggc ttgacggcgt ggtggagacc atttcaccgg ataccattca
    15781 ggataaagtg aaaccggaaa ttttctacta tcgcgtgttt atccgcaccc accaggacta
    15841 tctacaaaat aaatcaggac gccgtttttc gattgttcca ggcatgatcg ccacggtgga
    15901 tatcaaaacc ggtgaaaaaa ccattgtcga ctatttaatc aaaccgttta atcgcgcgaa
    15961 agaagcgctg cgcgagcggt aaatcgctga agataagaag atacgggggc tggtcacgcg
    16021 tgtcacaagt ctgttatact taccttacac attggggctg attctggatt cgacgggatt
    16081 tgcgaaaccc aaggtgcatg ccgaggggcg gttggcctcg taaaaagccg caaaaaaata
    16141 gtcgcaaacg acgaaaccta cgctttagca gcttaataac ctgcttagag ccctctctcc
    16201 ctagcctccg ctcttaggac ggggatcaag agaggtcaaa cccaaaagag atcgcgcgga
    16261 tgccctgcct ggggttgaag cgttaaaacg aatcaggcta gtctggtagt ggcgtgtccg
    16321 tccgcaggtg ccaggcgaat gtaaagactg actaagcatg tagtaccgag gatgtaggaa
    16381 tttcggacgc gggttcaact cccgccagct ccaccaaata aatcaagggg ttacgtgaaa
    16441 gcgtagccct tttttctttg gtagtggcgg caaaatggcg gcaggcattc agtcaagccc
    16501 agttgctact acatgcgatc gcaattacaa cttaaagagt ttcgcttgcc ctggattaac
    16561 agcttcgacg tagtttttga cccctattct gtgcggctca taattgcttg aatagaaatc
    16621 aatcaggaag tcactcattt tctgagatgt gactttcata actcccttac tcaaagttaa
    16681 attaaacacg ctaatctttg acgatggtgc ctgagtttta ctcatgttgg cttgataacc
    16741 agatttacgc attgccacta gtgcttcgtc gtaagccgct tgtaattggg ccaaattgtt
    16801 tgacgagatg atcacatcat ccataaacac acttagcttg agatcatgat gtttgttcaa
    16861 tcggcgtagt aagctaccaa aataactttt atctaagcag agggttgcaa gtattggaga
    16921 ttgaacaaaa ccaaaaggga ggacatgctt atgtggacta tgggacaagt ttcttacagt
    16981 tgaaaatgtt gagatttccc gcgcttgaga ataggtgaag tagctcttta gatcacgggt
    17041 gatacgacta cggctcgttg actgaaaaaa ttgtttaata tcaacaacgg caaaaaaatc
    17101 actttttaag tgtaatctgg cagctttaag atgcccacca gttcttagat ggtaaaaata
    17161 gagtggcgga atccacttgt ttctgacagc ctgaagtatc ttccctccga ctttacgtgc
    17221 ctcaacgctt gggacataaa cccaaacccc gggcttaatc tcaaatttat cttcccacct
    17281 ttgaacttct attgtcatga gttaaattgt tgtagttgaa ggccatgtta agaacggcgt
    17341 aaaccgcacc aactaagcca acaaacgcgg ttgcgcattt gagcatagcg gtgatcagtt
    17401 caacacgcgc cttaactaag ccaagttcgt ttgtatccat aacttgttcc tccatagata
    17461 cctgacgtct cttagcgcaa gcgcatggcc ctaactaaat aaaaaataac aaccagttag
    17521 cccagaaagc ttaacaagtc ggcgtccgat tacatggcaa ccaggtaatc ggtccgcagt
    17581 cgcaaagcga caaactacat atctacggag tggggataaa tccccgctaa cgtcaggcat
    17641 tgttaattta acctcaactt atagaaaagt atagttttaa atcatgtagt tatgtcgcca
    17701 tttaaatcgg caaacccacc tgtttaaatt tatg
//
LOCUS       DAJVBX010000086        17637 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.086, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000086 DAJVBX010000000
VERSION     DAJVBX010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 17637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17637
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.086"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            249..1817
                     /gene="cydA"
                     /locus_tag="OPV72_002453"
     CDS             249..1817
                     /gene="cydA"
                     /locus_tag="OPV72_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome ubiquinol oxidase subunit I"
                     /protein_id="HCR9914727.1"
                     /translation="MLDIVELSRLQFALTAMYHFLFVPLTLGMAFLLAIMETVYVLSG
                     KQIYKDMTKFWGKLFGINFALGVATGLTMEFQFGTNWSYYSHYVGDIFGAPLAIEGLM
                     AFFLESTFVGLFFFGWDRLSKVQHMCVTWLVALGSNLSALWILVANGWMQNPIAADFN
                     FETMRMEMVSFSELVLNPVAQVKFVHTVASGYVTGAMFILGISAYYMLKGRDFAFAKR
                     SFAIAASFGMAAVLSVIVLGDESGYEMGDVQKTKLAAIEAEWETQPAPASFTLFGIPD
                     QDKQENHLAIQIPYALGIIATRSVDTPVIGLKDLMVQHEERIRNGMKAYELLEQLRAG
                     STDQAVRDQFNSMKKDLGYGLLLKRYTPNVTDATEAQIQQATKDSIPRVAPLYFAFRI
                     MVACGFLLLAIIALSFWSVIRNRIGEKKWLLRAALYGIPLPWIAVEAGWFVAEYGRQP
                     WAIGKVLPTAVANSSLTVGDLLFSMFLICGLYTLFLVAELFLMFKFARLGPSSLKTGR
                     YHFEQSTVTSQPAR"
     gene            1833..2972
                     /gene="cydB"
                     /locus_tag="OPV72_002454"
     CDS             1833..2972
                     /gene="cydB"
                     /locus_tag="OPV72_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome d ubiquinol oxidase subunit II"
                     /protein_id="HCR9914728.1"
                     /translation="MIDYEVLRFIWWLLVGILLIGFAVTDGFDMGVGMLTRFLGRNDT
                     ERRIMINSIAPHWDGNQVWLITAGGALFAAWPMVYAAAFSGFYVAMILVLASLFFRPV
                     GFDYRSKIEDPRWRNMWDWGVFIGSFVPPLVIGVAFGNLLQGVPFHVDEYLRLYYTGN
                     FFQLLNPFGLLAGIVSVGMIITQGATYLQMRTVGELHLRARATSQIAALVTLVCFALA
                     GVWVMYGIDGYVVTSAIDHHAASNPLTKEVAREAGAWLVNFNNAPILWLVPALGVVLP
                     LLTILTSRMEKGAWAFLFSSLTLACIILTAGIAMFPFVMPSSTMMNASLTMWDATSSQ
                     MTLNLMTWVAAVFVPIILIYTSWCYWKMFGRITKEHIESNTHSLY"
     gene            2987..3100
                     /gene="cydX"
                     /locus_tag="OPV72_002455"
     CDS             2987..3100
                     /gene="cydX"
                     /locus_tag="OPV72_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome bd-I oxidase subunit CydX"
                     /protein_id="HCR9914729.1"
                     /translation="MWYFAWILGTLLACAFGIITALALEHVEAGKTGQEES"
     gene            3237..3518
                     /gene="ybgE"
                     /locus_tag="OPV72_002456"
     CDS             3237..3518
                     /gene="ybgE"
                     /locus_tag="OPV72_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyd operon protein YbgE"
                     /protein_id="HCR9914730.1"
                     /translation="MKYIYAVMDKRLLRALSFVMAIVLAGCMFWDPLRFAARTSTLEI
                     WHGLLLMWAVCAGIIHGVGFRPESVHWQGIFCPLLADIVLIVGLIFFFL"
     gene            3747..4151
                     /gene="ybgC"
                     /locus_tag="OPV72_002457"
     CDS             3747..4151
                     /gene="ybgC"
                     /locus_tag="OPV72_002457"
                     /EC_number="3.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tol-pal system-associated acyl-CoA thioesterase"
                     /protein_id="HCR9914731.1"
                     /translation="MNKYMFRWPIRVYYEDTDAGGVVYHASYVAFYERARTEMLRHHH
                     FSQQVLLAERVAFVVRKMTLEYYAPARLDDMLEVQTEITSMRGTALVFTQRIVNAENT
                     LLNEAEVLIVFVDPLKMKPRALPKSIVAEFKQ"
     gene            4148..4840
                     /gene="tolQ"
                     /locus_tag="OPV72_002458"
     CDS             4148..4840
                     /gene="tolQ"
                     /locus_tag="OPV72_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tol-Pal system protein TolQ"
                     /protein_id="HCR9914732.1"
                     /translation="MTDMNILDLFLKASLLVKLIMLILIGFSIASWAIIIQRTRILNA
                     AAREAEAFEDKFWSGIELSRLYQESQGRRDSLSGSEQIFYSGFKEFVRLHRANSHAPE
                     AVVEGASRAMRISMNRELETLETHIPFLGTVGSISPYIGLFGTVWGIMHAFIALGAVK
                     QATLQMVAPGIAEALIATAIGLFAAIPAVMAYNRLNQRVNKLELNYDNFMEEFTAILH
                     RQAFTVSESNKG"
     gene            4844..5272
                     /gene="tolR"
                     /locus_tag="OPV72_002459"
     CDS             4844..5272
                     /gene="tolR"
                     /locus_tag="OPV72_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015965300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin uptake protein TolR"
                     /protein_id="HCR9914733.1"
                     /translation="MARTRGRGRRELKSEINIVPLLDVLLVLLLIFMATAPIITQSVE
                     VDLPEANQSQAVSSNDDPPVIIEVSGVGQYSVVVDKDRMDQLPSEQVIAEVKRHLQAN
                     PKTVFLIGGAKEVPYDEIIKALNLLHSAGVKSVGLMTQPI"
     gene            5337..6467
                     /gene="tolA"
                     /locus_tag="OPV72_002460"
     CDS             5337..6467
                     /gene="tolA"
                     /locus_tag="OPV72_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope integrity protein TolA"
                     /protein_id="HCR9914734.1"
                     /translation="MSKATEQNDKLKRAIIISAVLHIILFAVLIWSSFDEHIEASAGG
                     GGGSAIDAVMVDPGAVVQQYNRQQDQQASARGAEEERKKLQQQQAEELQQKQAAEQER
                     LKQLEKERLAAQEQQKQAEEAAKLAQQQQQAEEAAKAAADAKKKAEAEAAKAAADAKK
                     KAEAEAAKAAADAKKKAEAEAAKAAAEAKKKAEAEAAKAAADAKKKADAEAAKAAAEA
                     KKKADAAAAKAAADAKKKAAAEKAAAAEGVDDLLGDLSSGKNAPKTGGGAKGNGQPSK
                     DSGTSGANGGTTGADISAYAKQIQVAIQSRLYDASLYQGKQCVLHISLAPDGSLKSIT
                     SEGGDPALCQAALMATKTAKIPKPPSQAVYEKIKDAKLDFKL"
     gene            6591..7883
                     /gene="tolB"
                     /locus_tag="OPV72_002461"
     CDS             6591..7883
                     /gene="tolB"
                     /locus_tag="OPV72_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001646851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tol-Pal system protein TolB"
                     /protein_id="HCR9914735.1"
                     /translation="MKQALRVAFGFLMLWAAVLHAEVRIEITQGVDSARPIGVVPFKW
                     AGPGAAPEDIGGIVAADLRNSGKFNPLDRSRLPQQPATAQEVQPTAWSALGIDAVIVG
                     LVTPNPDGSYNVAYQLVDTGGAPGTVLAQNSYKVNKQWLRYAGHTASDEVFEKLTGIK
                     GAFRTRIAYVVQTNGGQFPYELRVSDYDGYNQFVVHRSPQPLMSPAWSPDGSKLAYVT
                     FESGRSALVIQTLANGAVRQVASFPRHNGAPAFSPDGTKLAFALSKTGSLNLYVMDLA
                     SGQIRQITDGRSNNTEPTWFPDSQTLAFTSDQAGRPQVYKMNINGGAAQRITWEGSQN
                     QDADVSSDGKFMVMVSSNNGQQHIAKQDLVTGGVQVLSSTFLDETPSLAPNGTMVIYS
                     SSQGMGSVLNLVSTDGRFKARLPATDGQVKSPAWSPYL"
     gene            7918..8442
                     /gene="pal"
                     /locus_tag="OPV72_002462"
     CDS             7918..8442
                     /gene="pal"
                     /locus_tag="OPV72_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-associated lipoprotein Pal"
                     /protein_id="HCR9914736.1"
                     /translation="MQLNKVLKGLMIALPVMAIAACSSNKNASNDGSEGGMLNGAGTG
                     MDANGNGNMSSEEQARLQMQQLQQNNIVYFDLDKYDIRSDFAAMLDAHANFLRSNPSY
                     KVTVEGHADERGTPEYNISLGERRANAVKMYLQGKGVSADQISIVSYGKEKPAVLGHD
                     EAAYAKNRRAVLVY"
     gene            8452..9240
                     /gene="cpoB"
                     /locus_tag="OPV72_002463"
     CDS             8452..9240
                     /gene="cpoB"
                     /locus_tag="OPV72_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein CpoB"
                     /protein_id="HCR9914737.1"
                     /translation="MSSNFRHHLLSLSLLVGIAAPWAAFAQAPISSVGSGSVEDRVTQ
                     LERISNAHSQLLTQLQQQLSDNQSDIDSLRGQIQENQYQLNQVMERQKQIMLQLGSLN
                     NGGAAQPAAGDQSGAATAATPAPDAGTATSGAPVQSGDANTDYNAAIALVQDKSRQDD
                     AIVAFQNFIKKYPDSTYQPNANYWLGQLNYNKGKKDDAAYYFASVVKNYPKSPKAADA
                     MYKVGVIMQDKGDTAKAKAVYQQVINKYPGTDGAKQAQKRLNAM"
     gene            9405..9477
                     /locus_tag="OPV72_002464"
     tRNA            9405..9477
                     /locus_tag="OPV72_002464"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9438..9440,aa:Lys,seq:ttt)
     gene            9623..9698
                     /locus_tag="OPV72_002465"
     tRNA            9623..9698
                     /locus_tag="OPV72_002465"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9656..9658,aa:Lys,seq:ttt)
     gene            9833..9908
                     /locus_tag="OPV72_002466"
     tRNA            9833..9908
                     /locus_tag="OPV72_002466"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9866..9868,aa:Lys,seq:ttt)
     gene            10202..11245
                     /gene="nadA"
                     /locus_tag="OPV72_002467"
     CDS             10202..11245
                     /gene="nadA"
                     /locus_tag="OPV72_002467"
                     /EC_number="2.5.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000115355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HCR9914738.1"
                     /translation="MSVMFDSQAAIYPFPPKPTPLNDDEKQFYREKIKRLLKERNAVM
                     VAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHAASTLLVAGVRFMGETAKILSPEK
                     NVLMPTLAAECSLDLGCPIDEFSAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAV
                     ELIEHLDSLGEKIIWAPDRHLGNYVQKQTRADVLCWQGACIVHDEFKTQALTRLKKIY
                     PDAAILVHPESPRSIVEMADAVGSTSQLIKAAKTLPHRQLIVATDRGIFYKMQQAVPD
                     KELLEAPTAGEGATCRSCAHCPWMAMNGLKAIAEGLEQGGAAHEIQVDAALRESALLP
                     LNRMLDFAATLRV"
     gene            11270..11989
                     /locus_tag="OPV72_002468"
     CDS             11270..11989
                     /locus_tag="OPV72_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HCR9914739.1"
                     /translation="MDFFSTHNILIHIPIGAGGYDLSWIEAVGTIAGLLCIWLASLEN
                     ISNYFFGLVNVTLFAIIFFQIQLYASLLLQLFFFAANIYGWYAWSRQTKDNEAELKIR
                     WLPLPKAMAWLAICVIAIGLMTRYIDPVFAVLTRVAVAIMQMLGLQVTMPVLQPDAFP
                     FWDSCMMVLSIVAMILMTRKYVENWLLWVIINVISVVIFALQGVYAMSLEYLILTFIA
                     VNGSRLWINSARERGSRALSR"
     gene            complement(11986..12924)
                     /gene="zitB"
                     /locus_tag="OPV72_002469"
     CDS             complement(11986..12924)
                     /gene="zitB"
                     /locus_tag="OPV72_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family zinc transporter ZitB"
                     /protein_id="HCR9914740.1"
                     /translation="MAHSHSHADSHLPKDNNARRLLFAFIVTAGFMLLEVVGGILSGS
                     LALLADAGHMLTDAAALLFALLVVQFSRRPPTVRHTFGWLRLTTLAAFVNAIALVVIT
                     LLIVWEAIERFYTPRPVAGNLMMVIAVAGLLANLFAFWILHRGSDEKNLNVRAAALHV
                     MGDLLGSVGAIVAALIIIWTGWTPADPILSILVSVLVLRSAWRLLKDSVNELLEGAPV
                     SLDINALQRHLSREIPEVRNVHHVHVWMVGEKPVMTLHAQVIPPHDHDALLERIQDFL
                     MHEYHIAHATIQMEYQMCHGPDCHLNQTPSGHVHHH"
     gene            complement(13035..13421)
                     /locus_tag="OPV72_002470"
     CDS             complement(13035..13421)
                     /locus_tag="OPV72_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbgS-like family protein"
                     /protein_id="HCR9914741.1"
                     /translation="MKMTKLTTLLLTATLGLASGAALAAESNAQSSNGQANSAANAGQ
                     VAPDARQNVAPNDVNNNDINTNGNTNSTMQHPDGSTMNHDGMTKDEEHKNTMCKDGRC
                     PDINKKVETGNGVNNDVNTKTDGTTQ"
     gene            13741..14793
                     /gene="aroG"
                     /locus_tag="OPV72_002471"
     CDS             13741..14793
                     /gene="aroG"
                     /locus_tag="OPV72_002471"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase AroG"
                     /protein_id="HCR9914742.1"
                     /translation="MNYQNDDLRIKEINELLPPVALLEKFPATENAANTVAHARKAIH
                     KILKGNDDRLLVVIGPCSIHDPAAAKEYAARLLALRDELQGELEIVMRVYFEKPRTTV
                     GWKGLINDPHMDNSFQINDGLRIARKLLLDINDSGLPAAGEFLDMITPQYLADLMSWG
                     AIGARTTESQVHRELASGLSCPVGFKNGTDGTIKVAIDAINAAGAPHCFLSVTKWGHS
                     AIVNTSGNGDCHIILRGGKAPNYSAQHVAEVKEGLIKAGLTPQVMIDFSHANSCKQFQ
                     KQMEVCADVCQQIAGGEKAIIGVMVESHLVEGNQSLESGQPLTYGKSITDACIGWEDT
                     DALLRQLSAAVKARRG"
     gene            14946..16025
                     /locus_tag="OPV72_002472"
     CDS             14946..16025
                     /locus_tag="OPV72_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HCR9914743.1"
                     /translation="MTCQDKSLLAPGLASTPVIPRYRQIIRKRAVLMSAIALAMMVSL
                     MVDVTCGSSGLPLSALWQALFQPEKVNAGIHVIVWDIRLPYALMALLVGMALGLAGAE
                     MQTILNNPLATPFTLGVSSAAAFGAALAIVLGIGIPGIPAAWFIPANAFIFALLSALL
                     LDGITRWTGVAASGVVLFGIALVFTFNALVAIMQFVADEDTLQGLVFWTMGSLVRASW
                     EKLGVLAVVFIAVLFCALRSAWQLTALRLGEERAMSFGVHVRRLRLLSLLRISLLSAL
                     AVAFVGPIGFIGLVAPHIARILLGEDHRFYLPGSVLIGGLVLSLASIAAKNSIPGVMV
                     PVGIVTSLVGVPFFLSIVLRHRGSL"
     gene            16025..16801
                     /locus_tag="OPV72_002473"
     CDS             16025..16801
                     /locus_tag="OPV72_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR9914744.1"
                     /translation="MRRLMLRSFSAGYSTQPVIADLNVPLLPRGKITILLGPNGCGKS
                     TLLRSLAGLNNVDGEALLDGEDLMSLSFAERAQKVVFLPQSLPQGVHLHVLESIIVVL
                     RASGGRDNAQGRAQILAILEQLGITHLALQYLDQLSGGQRQLVGLAQSLIRRPELLLL
                     DEPLSALDLNYQFHVMDLVRRDTQAQNRVTIVVAHDINIALRHGDHVLMLKDGRLVAS
                     GAPETVITAERLAEVYRVRGRVERCSQGKLQVVLDGVIAV"
     gene            complement(16892..>17637)
                     /gene="gpmA"
                     /locus_tag="OPV72_002474"
     CDS             complement(16892..>17637)
                     /gene="gpmA"
                     /locus_tag="OPV72_002474"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000301556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HCR9914745.1"
                     /translation="TKLVLVRHGESQWNKENRFTGWYDVDLSEKGVSEAKAAGKLLKE
                     EGFSFDFAYTSVLKRAIHTLWNVLDELDQAWLPVEKSWKLNERHYGALQGLNKAETAE
                     KYGDEQVKQWRRGFAVTPPELTKDDERYPGHDPRYAKLSEKELPLTESLALTIDRVIP
                     YWNDTILPRMKSGERVIIAAHGNSLRALVKYLDNMSEDEILELNIPTGVPLVYEFDEN
                     FKPIKHYYLGNADEIAAKAAAVANQGKAK"
BASE COUNT         4046 a         4335 c         4942 g         4314 t
ORIGIN      
        1 tcgctgtcga aaaaagcaaa tctgacccac taaaaacctg tttattgtaa gggttttacg
       61 gcgtaatata tttgcgggat caatttgggt tttttattaa catgtttgta acttttcatc
      121 attactgttt ccttcccgag gggatagtac gatggaaggc cgcaaataaa tttgtattgg
      181 ggcatgcgtg tgaccctttc taacggggtt cactctcgga gtcttcatgc gatgagcaag
      241 gagtcatgat gttagatata gtcgaactgt cgcgcttaca gtttgccttg accgcgatgt
      301 accacttcct gtttgtgccg ctaacgctcg gtatggcgtt cctgctggcc attatggaaa
      361 cggtatacgt cctttccggc aaacagattt ataaagatat gaccaagttc tggggcaagt
      421 tgtttggtat caactttgct ctgggtgtgg ctaccggttt gaccatggag ttccagttcg
      481 ggacaaactg gtcgtactac tcccactatg ttggggacat cttcggtgcg ccgctggcca
      541 tcgaaggttt gatggccttc ttcctcgaat ccacctttgt aggtctgttc ttcttcggct
      601 gggatcgtct aagtaaagtt cagcatatgt gcgtcacctg gctggtggct ctggggtcca
      661 acctctccgc gttgtggatt ctggtagcga acggctggat gcaaaaccca atcgctgcgg
      721 atttcaattt cgaaaccatg cgtatggaaa tggtgagctt ctctgaactg gtgctgaacc
      781 cggtagcaca ggtgaaattt gttcacactg tggcgtccgg ctatgtcacc ggcgcgatgt
      841 tcatcctcgg tatcagcgct tactacatgc tgaaaggtcg tgacttcgcc tttgctaaac
      901 gctcctttgc tattgccgcc agcttcggta tggctgccgt actgtccgtt atcgtactcg
      961 gtgacgaatc cggttacgaa atgggcgacg tgcagaaaac caagctcgct gcgattgaag
     1021 ctgaatggga aacgcaacct gctccggcct cctttaccct gttcggcatt cctgaccagg
     1081 acaaacagga aaaccatctg gcgattcaga tcccttatgc gctcggcatt atcgctacgc
     1141 gttccgtgga cacgccggtt attggcctga aagatctcat ggttcagcat gaagagcgta
     1201 tccgtaacgg gatgaaagct tatgagctgc tggagcagct gcgcgccggt tctaccgacc
     1261 aggccgttcg cgaccagttt aacagcatga agaaagatct cggttacggc ctgctgctga
     1321 aacgctatac gcctaatgtg actgacgcga ccgaagcgca gatccagcaa gcgacgaaag
     1381 attctattcc tcgcgttgcg ccgctgtact tcgctttccg tatcatggtg gcgtgcggct
     1441 tcctgctgct ggcgattatc gcactttcct tctggagcgt gattcgtaac cgcatcggtg
     1501 agaaaaaatg gctgttgcgt gcggcgctgt acggtattcc actgccgtgg attgcggttg
     1561 aagcaggttg gttcgtcgcc gagtatggtc gtcagccgtg ggcgatcggc aaagtgttgc
     1621 cgacagccgt ggcgaactca tcgctgaccg tgggcgatct gctgttctcc atgttcctga
     1681 tttgcggcct gtataccctg ttcctggtgg cagaattgtt cctgatgttc aaatttgcac
     1741 gccttggccc aagcagcctg aaaaccggtc gctatcactt tgagcagtcc accgtgactt
     1801 ctcagccggc acgctaagac aggagtcgtc aaatgatcga ttatgaagta ctacgtttta
     1861 tctggtggct gctggttggc attttgctaa ttggtttcgc cgtcaccgat gggttcgaca
     1921 tgggggtggg gatgctcacc cgtttcctcg gtcgtaacga taccgaacgt cgaattatga
     1981 ttaactctat cgccccgcac tgggacggta accaggtgtg gttgatcacc gcgggcggcg
     2041 cgttgtttgc tgcctggccg atggtttacg ccgcggcgtt ctccggtttc tatgtggcga
     2101 tgatcctggt gctggcgtct ttgttcttcc gtccggtcgg ttttgattac cgttccaaga
     2161 ttgaagaccc gcgctggcgc aacatgtggg actggggcgt gttcatcggt agctttgtgc
     2221 cgccgctggt gattggcgtg gcctttggca acctgttgca gggcgtaccg ttccatgtgg
     2281 atgagtatct gcgtctgtac tataccggta acttcttcca gttgctgaac ccgtttggtc
     2341 tgctggcggg tatcgtaagc gtagggatga tcatcacgca gggggcgact tacctgcaaa
     2401 tgcgtaccgt tggcgaactg cacctgcgcg cgcgcgccac ctcgcagatt gcggcgctgg
     2461 tgacattagt gtgctttgcg ctggcgggcg tttgggtaat gtatggtatt gatggttatg
     2521 tcgtgacatc cgcgattgat catcatgctg cctctaaccc gctgactaaa gaagtggcgc
     2581 gcgaagccgg cgcctggcta gtgaacttta ataatgctcc gatcctgtgg ttggttccgg
     2641 ctctgggcgt ggttctgccg ctgctgacta tcctgacttc ccgtatggag aaaggcgcgt
     2701 gggcattcct gttctcttcg ctgacgttgg cctgcattat tctgacggcg ggtatcgcta
     2761 tgttcccatt tgtgatgccg tccagcacga tgatgaatgc cagtctgacc atgtgggatg
     2821 cgacatccag ccagatgacg ctgaacctga tgacctgggt tgcggcggtg ttcgtaccga
     2881 ttattctgat ctacaccagc tggtgttact ggaaaatgtt cggtcgtatc actaaagaac
     2941 atattgaaag caacacccac tctctgtact aagtaaggag cttaaaatgt ggtatttcgc
     3001 atggattctg ggaacgcttc ttgcctgtgc attcgggatc attaccgccc tggcgcttga
     3061 gcacgttgaa gcgggtaaaa ccggtcaaga agaaagctaa tgattcatat tgtcgctatg
     3121 caatatacaa aatcatttaa gttgcatcgc ggcggcaagg ctgcgaatcc ccaggagctt
     3181 acatcagtaa gtgactgggg tgagcagccg cagccaacaa agaggcagct tagaggatga
     3241 agtatattta tgcggtaatg gacaagcgcc tcttaagggc gctttccttc gtgatggcga
     3301 tagtgctggc aggatgtatg ttctgggacc cgttacggtt tgccgccagg accagcacgc
     3361 ttgaaatctg gcacggatta ttgctgatgt gggcggtttg cgcaggcata atccacggcg
     3421 tgggttttcg ccctgaatcc gtacactggc aagggatttt ttgtccgctc cttgcggata
     3481 tcgtccttat cgtcggcctg attttcttct tcttgtgaat aagaaacctc cttaaaaata
     3541 taggggcttg cataagccca tatattttta ctctccctta acttcccccc attcccaagc
     3601 ctcattccta cgcgtatagt agcaacgttt aaaagctcta cttttgttgc attaccggga
     3661 tgtaaagtga atacaaggcg atatacaacg gcattcttga ggcattacgg cggcaagcgg
     3721 atgacgccaa caaagaggct gcagggatga ataagtatat gtttcgatgg ccaattcgag
     3781 tttattacga agacacggac gccggcggtg tggtttatca cgccagctat gtcgcttttt
     3841 atgaaagagc gcgcacggag atgctgcgtc accatcactt cagccaacag gtgctgctgg
     3901 cggagcgggt cgcctttgtg gtgcgcaaga tgacgctgga atactatgcg cctgcgcggc
     3961 tcgacgatat gcttgaagtt caaacagaaa ttacgtcaat gcgtggcacc gctttggttt
     4021 tcacgcaacg cattgtcaac gcagagaaca cgctgctaaa tgaagcagag gttctgattg
     4081 ttttcgttga tccactcaaa atgaagcctc gtgcgcttcc taagtctatt gtcgcggagt
     4141 ttaagcagtg actgacatga atatccttga tttgttcctg aaggcaagcc ttctagttaa
     4201 acttatcatg ttgattttga ttggtttttc aatagcatcc tgggccatca ttatccagcg
     4261 aacgcgtatc ctgaacgccg ctgcgcgtga ggcggaagcg tttgaagata aattctggtc
     4321 cggaatcgaa ctatcgcgtc tgtaccagga aagccagggg agacgcgata gtctgtcggg
     4381 ctcggaacaa atcttttata gcgggttcaa agagtttgtc cggctccatc gcgccaacag
     4441 ccatgcgccg gaggcagtgg tagagggggc gtcgcgtgcg atgcgcatct ccatgaaccg
     4501 agagctggaa acgctggaaa cgcatatccc gtttcttggc acggtaggct ctatcagtcc
     4561 ttatatcggt ctgtttggca ccgtatgggg gattatgcat gcgtttatcg ccctgggtgc
     4621 ggtgaaacag gcgactctgc aaatggttgc gccgggtatt gccgaagcat tgattgccac
     4681 ggcgattggt ctgtttgccg ctatccctgc ggttatggct tacaaccgac tgaatcagcg
     4741 cgtgaacaag ctggaactga attacgacaa ctttatggaa gagtttaccg cgattctgca
     4801 ccgccaggcg tttaccgtaa gcgaaagcaa caaggggtaa gccatggcca gaacgcgtgg
     4861 acgaggtcgt cgcgaactta agtccgaaat caatatcgta ccgctactcg acgtactgtt
     4921 ggtgctgctg ctgatcttta tggcaaccgc gccgatcatt acccagagcg tggaagtcga
     4981 cttaccggag gcgaatcagt cgcaggcggt cagtagtaac gacgatccgc cggtcattat
     5041 tgaggtttcc ggagtagggc aatacagcgt agtggttgat aaagatcgaa tggatcaact
     5101 gccgtctgaa caggtgatcg cagaagtaaa gcgtcatctg caggctaatc cgaaaacagt
     5161 ctttttaatc ggcggcgcga aagaggtgcc gtacgatgaa ataattaaag cgctgaactt
     5221 gttacacagc gcgggcgtaa aatcggttgg cttaatgacg cagccaatct gaagtctgcg
     5281 tcccgttggc ttgaaagacg gcgagtaaca ggcgaacagt tttttgggaa ccgagagtgt
     5341 caaaggcaac cgaacaaaac gacaagctca aacgggcgat aattatttca gccgtgctgc
     5401 atatcatctt atttgcagtg ctgatctgga gttcgtttga tgagcatata gaggcttctg
     5461 ccggcggcgg cggcggttcc gctatcgacg cggtgatggt cgatcctggc gccgttgtgc
     5521 agcagtacaa ccgtcagcag gatcaacagg ccagtgccag aggcgcggaa gaagagcgta
     5581 aaaagctgca acagcagcaa gcagaggagc tgcagcagaa gcaggctgct gaacaggagc
     5641 ggttgaaaca acttgagaaa gaacgtttag cggctcagga gcagcaaaag caggctgaag
     5701 aagcggcaaa actggcgcaa cagcagcaac aggccgaaga agcggcgaaa gcggcggcgg
     5761 acgcgaagaa gaaagcggag gccgaggcgg cgaaagcggc ggcggacgcg aagaagaaag
     5821 cagaggccga ggcggcgaaa gcggcggcgg acgcgaagaa gaaagcagag gccgaagcgg
     5881 cgaaagcagc ggcggaggcg aagaagaaag cggaggccga agcggcgaag gcagcggcgg
     5941 acgctaagaa gaaagcggat gccgaggcgg cgaaagcggc ggcggaggcg aagaagaaag
     6001 cggatgccgc ggcggcgaaa gcagcggcgg acgctaagaa gaaagcggct gccgaaaaag
     6061 cggccgccgc agaaggcgtc gacgatctgc ttggcgatct cagctcgggt aagaatgcgc
     6121 cgaaaaccgg cggcggcgcg aaagggaatg gtcagccatc gaaagatagc ggtacatcgg
     6181 gcgctaacgg tgggacgaca ggcgctgata tcagcgccta cgcgaaacag attcaggtcg
     6241 ccattcagag ccgtctgtat gatgcgagcc tgtatcaggg caaacaatgt gtcttgcata
     6301 ttagcctggc gccggatggc tcattaaaaa gcattacgtc tgagggcggc gatccggcgc
     6361 tttgtcaggc ggcgttaatg gcgacaaaaa ccgcgaaaat tcctaaaccg ccaagccagg
     6421 ctgtttatga gaaaataaag gatgccaaac tagactttaa actgtagata cttttcttta
     6481 tggaagttgg agcggttgag ttgttactgg tcctggtggt tttgtgtatt tgagtttgtt
     6541 aacattctgc taaattatcg tgggtcgcag gcccaggtat gggagatatg atgaagcagg
     6601 cattacgagt agcatttggt tttctgatgc tgtgggcggc agtgctgcac gcagaagtcc
     6661 gtatcgagat cacccagggg gtggactcgg cgcgaccgat tggcgttgtg ccttttaaat
     6721 gggccgggcc gggcgctgcg cctgaagata tcggcggcat cgtggcggca gatttacgca
     6781 atagcggtaa atttaatccg ttagaccggt cccgactgcc gcagcagcca gccaccgctc
     6841 aggaagttca gcctaccgca tggtctgcgc tgggtattga tgccgtcatc gttggactgg
     6901 tcacgccgaa tccggacggt tcgtacaatg ttgcttatca gctggttgac actggcggtg
     6961 cgccggggac tgtactggcg caaaactcct ataaagtgaa caagcagtgg ctgcgttatg
     7021 caggccacac cgccagtgac gaagtctttg aaaaactgac gggcattaag ggcgcgttcc
     7081 gtactcgtat cgcctatgtg gtacagacta acggcggtca gttcccgtat gaactgcgtg
     7141 tgtcggatta cgatggctac aatcagttcg tagtgcaccg ttctccgcag ccgttgatgt
     7201 ctccggcgtg gtctccggac ggctcaaaac tggcttacgt gacttttgaa agcggtcgct
     7261 ccgcgctggt tatccagacg ctggcaaacg gcgcagtgcg tcaggttgcg tccttcccgc
     7321 gtcacaacgg cgcgccggcc ttctcgccgg atgggacgaa actggcgttc gcgttatcga
     7381 aaaccggaag tctgaacctg tacgttatgg atctcgcctc cggtcagatt cgtcagataa
     7441 cggacgggcg tagcaacaat acggagccga cctggttccc ggacagccag actctggcct
     7501 ttacttctga ccaggctgga cgtccgcaag tgtataaaat gaacattaac ggcggtgcgg
     7561 cgcagcgtat tacctgggaa ggttcgcaaa accaggatgc ggatgtcagc agcgacggta
     7621 aatttatggt aatggtaagc tcaaataacg ggcagcagca cattgccaaa caagatctgg
     7681 tgacgggtgg cgtacaggtt ctgtcgtcaa cgttcctgga tgaaacgcca agtctggcac
     7741 ctaacggcac gatggtaatc tacagctctt ctcaggggat gggatctgtg ctgaatttgg
     7801 tttctacaga tgggcgtttc aaagcgcgtc ttccggcaac tgatggtcag gtgaaatcgc
     7861 ctgcctggtc gccgtatctg tgataataat taattgatta ctaaaggaat taaagaaatg
     7921 caactgaaca aagtgctgaa gggcctgatg attgccctgc ctgttatggc aatcgcggca
     7981 tgttcttcca acaagaacgc cagcaatgac ggtagcgaag gcggcatgct gaacggcgcc
     8041 ggcactggta tggacgctaa cggcaacggc aacatgtcat ctgaagagca agcgcgtctg
     8101 cagatgcagc agctgcagca gaacaacatc gtttacttcg atctcgacaa gtacgatatc
     8161 cgttctgact tcgcggcaat gctggatgcg cacgctaact tcctgcgtag caacccgtct
     8221 tacaaagtca ccgtagaagg tcacgcggac gaacgcggta ctccggagta caacatctcc
     8281 ctgggcgaac gtcgtgctaa cgccgttaaa atgtacctgc agggtaaagg cgtttccgct
     8341 gaccagatct ccatcgtttc ttacggtaaa gaaaaacctg ccgtactggg ccacgacgaa
     8401 gcggcttacg ctaagaaccg tcgcgctgta ctggtttact aagagaattg catgagcagt
     8461 aacttcagac atcacctgtt gagtctgtcg ttactggttg gcatagcggc cccttgggcc
     8521 gcttttgctc aggcgccaat cagtagtgtc ggctcaggct cggtcgaaga ccgcgtcact
     8581 caacttgagc gtatctctaa cgctcacagc cagcttttaa cccaacttca gcagcagctc
     8641 tccgataatc agtctgatat cgattctttg cgcggccaaa tccaggaaaa tcagtatcaa
     8701 ctgaatcagg tgatggagcg ccagaagcaa attatgctgc agctggggag tttaaataat
     8761 ggcggcgcag cgcagccagc agctggcgac cagagcgggg cggcaaccgc tgcgaccccc
     8821 gctccggatg ccggtacggc aacctcaggg gcgccggtac aaagtggcga tgcgaatacc
     8881 gattacaatg cggcaattgc gctggtgcag gataagtctc gccaggatga tgcgattgtg
     8941 gcgtttcaga acttcatcaa gaaataccct gattctactt atcagccgaa cgccaattat
     9001 tggctgggcc agttgaatta caacaagggt aaaaaagatg acgccgccta ttatttcgcc
     9061 tcggtagtaa aaaactatcc taagtcgccg aaggctgcgg acgcgatgta caaagttggc
     9121 gttatcatgc aggacaaagg tgatacggca aaagcgaaag cggtttatca gcaggtgatt
     9181 aacaaatatc ctggcactga tggcgcgaaa caggcgcaga agcgtcttaa cgcgatgtaa
     9241 tgcgtaccat gcgaccagaa aacgcctttt ttctggtcgc gtcgtgcgat tcctaagcag
     9301 ttgagccctc tgcgtcgaaa tttttgttgc gctcaaatct gaaatcagta atatatgccg
     9361 ccgttgccac gggatattaa acaactcgaa agcaacgtaa aagtgggtcg ttagctcagt
     9421 tggtagagca gttgactttt aatcaattgg tcgcaggttc gaatcctgca cgacccacta
     9481 atttaacatc aaactcagat gttgaacgtg aaggataacg ttgcgtcagc aacggcccgt
     9541 agggcgaggc gaagccgagt catcctgcac gacccaccat ctttagatgg tccgagtaaa
     9601 atctttcagg cagcacccgt atgggtcgtt agctcagttg gtagagcagt tgacttttaa
     9661 tcaattggtc gcaggttcga atcctgcacg acccaccaat atacaaggtg gtaactggta
     9721 gagaacgtga aggataatgt tgctttagca acggcccgaa gggcgaggcg aagccgagtc
     9781 atcctgcacg acccaccatc ctgaatgatt gaagcagtaa cccttatcca aggggtcgtt
     9841 agctcagttg gtagagcagt tgacttttaa tcaattggtc gcaggttcga atcctgcacg
     9901 acccaccaat gtaaaaaagc gccctaaagg cgcttttttg ctatctgcga tatggaagat
     9961 tcgaacctgc cgcaggttcg ggtcttgcct gatgcgctgc gcttatcagg cctacagacg
    10021 gcaccgctca cgtaggccag ataagacgtt acgccgccat cagatacgga ctacgtaatt
    10081 attgtgactt tccttattga atcagctatc ttgtttagca tataaaacaa attgaccgat
    10141 tgtggcgttt attacgcttt cattcggttg tttcgttaag tcagtaaaac gagaagccac
    10201 gatgagcgta atgtttgact cacaagccgc aatctacccg ttcccgccga aaccaacgcc
    10261 gttgaacgac gatgaaaagc aattttatcg tgagaaaatc aagcgtttgc tcaaagagcg
    10321 caatgccgtc atggtggcgc actactacac cgatccggaa attcaacagt tagcagaaga
    10381 aaccggcggc tgtatttccg actcgctgga aatggcccgt ttcggcgcga agcacgccgc
    10441 atccacgtta ctggtagcgg gcgtacggtt tatgggggaa accgccaaaa tcctcagccc
    10501 ggaaaaaaac gttcttatgc ctacgctggc ggcggaatgt tcgctggatt taggctgccc
    10561 aatagacgaa tttagcgctt tttgtgatgc gcaccctgac agaaccgtag tggtctatgc
    10621 taacacctcg gctgctgtta aagcgcgtgc ggactgggtt gtgacctcca gtatcgccgt
    10681 agaactgatt gagcatctgg atagtttggg ggaaaaaatt atctgggcgc cggacagaca
    10741 cctggggaat tacgtgcaaa aacagaccag ggccgatgta ctgtgttggc aaggggcgtg
    10801 tatcgtgcat gacgagttta aaacccaggc gttgacccgt ttaaaaaaaa tctatcccga
    10861 tgccgctatt ctggttcacc ctgaatcgcc gcggtccatt gtcgagatgg ccgatgcggt
    10921 gggctccacc agtcagctta ttaaggcggc aaaaacgctg ccgcacagac agcttatcgt
    10981 cgcgaccgat cgcggcatct tctacaaaat gcagcaggcg gttccggata aagagttgct
    11041 tgaagcacca acggcgggcg aaggggcaac ctgtcgcagc tgcgcgcatt gtccgtggat
    11101 ggcgatgaac ggcctgaaag ccattgctga agggctggag cagggaggcg cggcgcatga
    11161 aatacaggtt gatgcggcgc tacgcgagag cgcattactt cccctcaacc ggatgctgga
    11221 ttttgcggct acacttcggg tgtaaagacg gaaatctttg ggggagagaa tggatttttt
    11281 tagtacgcac aacatactga ttcatattcc gattggcgct ggcgggtacg atctctcatg
    11341 gatcgaagcg gtaggaacca tcgccggcct gctctgtatt tggcttgcca gtctggagaa
    11401 tatcagcaac tacttttttg gactggttaa cgtcaccctg tttgcgatta ttttctttca
    11461 gatccagctt tatgccagcc tgttgctgca actctttttc tttgccgcca atatttatgg
    11521 ctggtatgcg tggtcgcggc aaacaaagga taatgaggcc gagcttaaaa tacgctggct
    11581 gccgttgcca aaagcaatgg catggctggc gatatgtgtg atagctatcg gtttgatgac
    11641 gcgatatatc gatcccgtat tcgccgtcct gacgcgcgtg gccgtcgcca ttatgcagat
    11701 gctggggtta caggtgacaa tgcctgtact gcaaccggac gctttcccgt tctgggactc
    11761 ttgcatgatg gtgctgtcta tcgtggcgat gattttgatg acacgcaaat atgtcgaaaa
    11821 ctggctcctg tgggtgataa tcaacgtaat cagtgtggtg atttttgctt tgcagggcgt
    11881 ctatgcgatg tcgctggaat atctgatcct gacatttatc gccgtgaacg gtagtcgcct
    11941 gtggataaac agcgcgcggg agcgaggatc gcgcgcgctt tcccgttaat ggtgatgaac
    12001 atgcccggat ggcgtctgat tcaggtgaca gtccgggccg tgacacattt gatactccat
    12061 ttgaatcgta gcgtgcgcaa tatggtattc gtgcatcagg aaatcctgga tacgttccag
    12121 cagcgcatca tggtcgtgtg gcggaatgac ctgagcgtgc aatgtcatga ctggtttttc
    12181 gccgaccatc cagacatgca catggtgtac gttgcggact tcggggattt cccggcttaa
    12241 atggcgctgt aaggcattaa tatccagtga aaccggcgcg ccttccagca attcgttgac
    12301 gctatctttt aacaaacgcc aggcgctgcg tagtaccagt accgaaacca gaatagagag
    12361 aatcgggtcc gctggcgtcc agcccgtcca gataatgatc aacgcggcga ctattgcgcc
    12421 gacggaaccc agcaaatcgc ccatcacatg tagcgcggca gcgcgcacgt tcaggttttt
    12481 ttcatcgctt ccccgatgga gtatccagaa cgcaaacagg ttcgccagca gacccgcgac
    12541 cgcaatcacc atcatcagat tgcccgccac cggacgtggc gtgtaaaagc gctctatcgc
    12601 ttcccagaca atgagaaggg taatgaccac caacgcaatg gcattcacaa aggccgccag
    12661 tgtggtgagt cttagccagc caaaagtgtg gcgaacagtc ggggggcgac gggaaaattg
    12721 aaccaccagc agcgcaaaga gaagagccgc cgcgtcggtg agcatatgtc ccgcatccgc
    12781 caacaacgcc agagagccgg agagtatccc gcccaccacc tcaaggagca taaatccggc
    12841 agtgacgata aaggcgaaaa gcaggcgacg agcattatta tctttcggca ggtgtgaatc
    12901 ggcatgagag tgtgagtgcg ccataacgtc attcctttgt tattctcatc aatactgtag
    12961 atatcatact gatttttcgc tgacaaaata aaaaggagag cgaaagctct cccgttatca
    13021 gacttttttc tgaattactg cgtggtaccg tcggttttgg tattcacgtc attattgacg
    13081 ccattaccgg tttccacttt tttattaata tccgggcagc gaccatcttt acacatggta
    13141 tttttatgct cttcatcctt ggtcattccg tcatgattca tggttgaacc gtcaggatgc
    13201 tgcatcgtgc tgttagtatt gccgttggta ttgatgtcgt tgttattcac atcattcggc
    13261 gccacattct ggcgggcgtc cggggcaacc tgaccggcat ttgccgccga gttcgcctgg
    13321 ccattactgg actgcgcgtt agattcagca gctaacgctg cgccgctggc aaggccgagg
    13381 gtagcggtga gtaaaagcgt agtcagtttt gtcattttca taagatgctc ctgttatggt
    13441 ggatatgtcg gataacctct tccaacagtg cacgtgtcag tcaaatcctc aaataaggga
    13501 taaaaagcgt tcgccgccgc gggttaacgc agcagagaat cttgcaataa ttcataaaca
    13561 gagtggttac agttaaaaag tgtaggttag atcccatttt ccgctacatt tgtgcgtttt
    13621 tttcctgaat tccaggatta ttccgttcaa agtgtaaaag cccgtttaca ctatttaatt
    13681 gaagagatag attggaggga ttgcattcat tgggataagt acggcaacat tggaataaac
    13741 atgaattatc agaatgacga tttacgcatt aaagaaatca acgagttatt acctccggtc
    13801 gcgctgctgg aaaagtttcc cgccacggaa aatgcagcaa ataccgttgc tcacgcacgc
    13861 aaagccatcc ataaaattct caaaggcaat gacgatcgtc tgctggtggt gatcggtcct
    13921 tgttcaattc atgatccggc agcggcgaaa gagtatgccg cccgtttgct ggcgctacgc
    13981 gatgagcttc aaggcgagct tgaaattgtc atgcgcgtct attttgagaa accgcgtact
    14041 accgtcggct ggaaagggct gattaacgat ccgcacatgg ataacagctt ccagattaac
    14101 gacggtctgc gtattgcgcg caaactgctg ctggatatta acgacagcgg cctgcctgcc
    14161 gccggcgaat tcctcgatat gatcacgccg caatatctgg ccgatctgat gagctggggc
    14221 gccattggcg cacggactac tgaatcccag gttcatcgcg aactggcgtc tggcctctct
    14281 tgtccggtcg gttttaaaaa tggtactgat ggcacgatta aagtcgccat tgacgccatc
    14341 aacgccgccg gcgcgccgca ttgcttcctc tccgtcacta aatggggtca ttcggcgatt
    14401 gtgaatacca gcggcaacgg cgactgccat atcattctgc gcggcggtaa agcgccaaac
    14461 tatagcgcgc aacatgttgc tgaggtgaaa gaaggcctca tcaaagcggg actgacgccg
    14521 caggtcatga tcgatttcag ccatgccaac tcctgtaagc aatttcaaaa gcagatggag
    14581 gtttgcgccg atgtctgtca gcagatagcg ggcggtgaaa aagcgattat tggcgtgatg
    14641 gtagagagtc atctggtaga aggaaaccag agtctggaaa gcggtcagcc gctgacctac
    14701 ggtaaaagca ttactgacgc ctgtattggc tgggaagata ccgatgcgct gcttcgtcag
    14761 ttgtcggcag cggtaaaagc ccgtcgaggt taatcttcat tacgtcttaa accggcccgc
    14821 aaggccggtt ttttactgga aaccgatgag atagcccacc gtgtcatcaa tcgaaatata
    14881 aataaatata taacgaaata attcggcgct ataattctct tctgattaat aacgtcgctc
    14941 gaaccatgac ctgtcaggac aaatcacttt tagcccccgg tctcgcttcc acgcccgtca
    15001 ttccgcgcta tcgccagatc atacgcaaac gggccgtgct catgtcagct attgcgctgg
    15061 cgatgatggt ttcactgatg gtggatgtaa cctgtgggtc ttctggttta ccgctcagtg
    15121 cgctgtggca ggcgcttttc cagccggaaa aggtgaatgc gggcatacac gttattgtct
    15181 gggatatccg cttaccctat gccctgatgg ccctactggt gggcatggcg ttagggttag
    15241 cgggcgccga aatgcaaacc attttaaata atccgctggc gacgccgttt acccttggcg
    15301 tatcgtccgc ggcggctttt ggcgctgcgc tggcgattgt gttggggatc ggtattcccg
    15361 gtattcctgc cgcctggttt atcccggcca atgcgttcat ctttgcgctt ttatccgcgt
    15421 tactcctgga cggtattacc cgttggacag gcgtcgccgc atccggagtg gtgttgttcg
    15481 gtattgcgct ggtattcacc tttaacgcgt tggtcgccat tatgcagttt gtggctgatg
    15541 aagatacgct gcaggggctg gtattctgga cgatggggag cctggtccgc gcgtcgtggg
    15601 aaaaattggg cgtactggcc gtggtgttta ttgctgtgct tttttgcgcg ttacgaagcg
    15661 cctggcaact cacggcatta cgtctgggcg aagagagggc gatgagcttt ggggttcatg
    15721 tccgccgttt acgcctgctg tcattgttgc gtatcagctt gttatcagcg ctggcggtag
    15781 ctttcgtcgg gccgattggt tttattggtc tcgttgcgcc gcacattgcg cgaatactgt
    15841 tgggggaaga tcaccgtttc taccttccgg gcagcgtgct gataggcggg ctggtgttat
    15901 cgctggcctc tattgcggcg aaaaatagta ttccgggcgt catggtgccg gtggggattg
    15961 tcacctcgct ggtcggggtt ccgttctttt taagcattgt attgcgacat cgggggagtc
    16021 tctgatgcgc aggttaatgc tccgctcatt tagcgccggc tattccactc agccggttat
    16081 tgcagatctc aacgttccct tactgccgcg cgggaaaatt accattttgc tggggccgaa
    16141 cggctgtggt aaatcgacgt tactacgttc gctggccggg ctgaataacg tcgacggcga
    16201 ggcgctgctt gatggcgaag atctcatgtc gttatcgttt gccgagcggg cgcagaaagt
    16261 tgtgtttttg ccgcagtcat taccgcaggg cgtacatctg catgtactgg agtcgattat
    16321 cgtggtactg cgggcatcag gcggcagaga caatgcgcag ggcagagcgc agatactggc
    16381 tatccttgag caattgggca taacgcatct ggcgttgcag tatctcgacc agctttccgg
    16441 cggtcagcgg cagttagtgg gtctggcgca atcgctgatt cgtcgccctg aacttctgtt
    16501 gctggatgag ccgctcagcg cgctggattt aaactatcag tttcacgtaa tggatctcgt
    16561 gcgtcgggat acccaggcgc aaaatagggt gacgatagtc gtggcgcatg acattaatat
    16621 tgccctgcgt catggtgacc atgtcctgat gctaaaagac ggcaggctgg tcgccagcgg
    16681 cgcgccggag acggtgatta ctgcggagcg tctggctgaa gtgtaccggg tacgaggacg
    16741 cgtggagcgc tgttcgcagg ggaaattgca ggtggtgctg gacggcgtga tcgctgttta
    16801 agacatattg cctgatggcg ctgcgcttat ccggcctacc cattgctcgt aggccggata
    16861 aggcagttat accgccatcc ggcaaaggtg attacttcgc tttaccctga ttcgccacgg
    16921 cagccgcttt cgcggcgatt tcgtcagcgt tacccagata gtaatgtttg atcggcttga
    16981 agttttcgtc gaactcatac accagcggca cgccggtcgg gatgtttaac tcaagaatct
    17041 catcttcact catgttatcc aggtatttca ccagcgcacg caatgagtta ccgtgagcgg
    17101 cgatgatcac gcgctcaccg ctcttcatac gcggcaggat ggtgtcgttc cagtaaggaa
    17161 taacgcggtc gatggtcagc gccagacttt cggtcaacgg cagctctttc tcgctcagtt
    17221 tggcataacg tggatcgtga cccggataac gctcatcatc tttggtcagt tccggcggcg
    17281 tcacggcaaa accgcggcgc cactgcttaa cctgctcgtc accatatttt tctgccgttt
    17341 ccgctttatt cagcccttgc aacgcgccat agtgacgttc attgagtttc caggattttt
    17401 ccaccggcag ccacgcctga tccagttcat ccagtacgtt ccacagcgta tggatagcgc
    17461 gtttcagtac ggaagtgtag gcaaaatcaa agctgaaacc ttcttctttt agcagtttac
    17521 ccgctgcttt tgcttcgctt acgccttttt cagacaggtc aacatcatac cagccggtga
    17581 aacggttctc tttgttccat tgactttcac cgtgacgtac cagaaccagc ttagtta
//
LOCUS       DAJVBX010000087        17502 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.087, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000087 DAJVBX010000000
VERSION     DAJVBX010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 17502)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17502)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17502
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.087"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(138..3011)
                     /gene="gcvP"
                     /locus_tag="OPV72_002475"
     CDS             complement(138..3011)
                     /gene="gcvP"
                     /locus_tag="OPV72_002475"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase"
                     /protein_id="HCR9914746.1"
                     /translation="MTQTLSQLENRGAFIERHIGPDAAQQQEMLNAVGAESLNALTGQ
                     IVPKDIQLATPPQVGEAATEYAALAELKAIAGRNKRFTSYIGMGYTAVQLPPVILRNM
                     LENPGWYTAYTPYQPEVSQGRLEALLNFQQVTLDLTGLDMASASLLDEATAAAEAMAM
                     AKRVSKLKNANRFFVAADVHPQTLDVVRTRAKTFGFDVIVDDADKVLDHQDVFGVLLQ
                     QVGTTGEIHDYGTLISELKARKVIVSVAADFMALVLLTAPGKQGADIVFGSAQRFGVP
                     MGYGGPHAAFFAAKDEFKRSMPGRIIGVSKDAAGNTALRMAMQTREQHIRREKANSNI
                     CTSQVLLANIASLYAVYHGPVGLKRIANRIHRLTDILAAGLQQKGLKLRHAHYFDTLC
                     VEVADKAAVLARAEAAEINLRSDIHNAVGITLDETTTRENVAQLFNVLLGDSHGLNIE
                     TLDKDVALDSRSIQQGMLRDDAILTHPVFNRYHSETEMMRYMHSLERKDLALNQAMIP
                     LGSCTMKLNAAAEMIPITWPEFAELHPFCPPEQAEGYHQMISQLSDWLVKLTGYDAVC
                     MQPNSGAQGEYAGLLAIRHYHGSRNEGHRDICLIPASAHGTNPASAHMAGMQVVVVAC
                     DKNGNIDLDDLRAKAEQHAANLSCIMVTYPSTHGVYEETIREVCEVVHQFGGQVYLDG
                     ANMNAQVGITSPGFIGADVSHLNLHKTFCIPHGGGGPGMGPIGVKAHLAPFVPGHSVV
                     QIEGMLTRQGAVSAAPFGSASILPISWMYIRMMGAEGLKQASQVAILNANYIASRLKD
                     AYPVLYTGRDGRVAHECILDIRPLKEETGISELDIAKRLIDYGFHAPTMSFPVAGTLM
                     VEPTESEGKAELDRFIDAMLAIRAEIDQVKAGVWPLEDNPLVNAPHIQSELVAEWAHP
                     YSREVAVFPAGVADKYWPTVKRLDDVYGDRNLFCSCVPISDYQ"
     gene            complement(3174..3563)
                     /gene="gcvH"
                     /locus_tag="OPV72_002476"
     CDS             complement(3174..3563)
                     /gene="gcvH"
                     /locus_tag="OPV72_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HCR9914747.1"
                     /translation="MSNVPAELKYSKEHEWLRKEADGTYTVGITEHAQELLGDMVFVD
                     LPEVGATVSAGDDCAVAESVKAASDIYAPVSGEIVAVNDALSDSPELVNSEPYAGGWI
                     FKIKASDESELESLLDATAYEALLEDE"
     gene            complement(3589..4683)
                     /gene="gcvT"
                     /locus_tag="OPV72_002477"
     CDS             complement(3589..4683)
                     /gene="gcvT"
                     /locus_tag="OPV72_002477"
                     /EC_number="2.1.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system aminomethyltransferase
                     GcvT"
                     /protein_id="HCR9914748.1"
                     /translation="MAQQTPLYEQHTLCGARMVDFHGWMMPLHYGSQLDEHHAVRTDA
                     GMFDVSHMTIVDLHGSRTREFLRYLLANDVAKLTKTGKALYSGMLNASGGVIDDLIVY
                     YFTEDFFRLVVNSATREKDLSWITQHAEPYAIDITVRDDLSLIAVQGPNAQEKAATLF
                     TDQQRHAVEGMKPFFGVQAGDLFIATTGYTGEAGYEIAMPNEKAADFWRALVEAGVKP
                     CGLGARDTLRLEAGMNLYGQEMDEGISPLAANMGWTIAWEPADRDFIGREALEMQREK
                     GHEQLVGLVMTEKGVLRNELPVRFTDAQGNQQEGIITSGTFSPTLGYSIALARVPAGI
                     GETAIVQIRNREMPVKVTKPVFVRNGKAVA"
     gene            complement(5138..6340)
                     /gene="ubiI"
                     /locus_tag="OPV72_002478"
                     /gene_synonym="visC"
     CDS             complement(5138..6340)
                     /gene="ubiI"
                     /locus_tag="OPV72_002478"
                     /gene_synonym="visC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent 2-octaprenylphenol hydroxylase"
                     /protein_id="HCR9914749.1"
                     /translation="MQSVDVAIVGGGMVGLAVACGLQGSGLRVAVLDHVVPQQLANDA
                     PPQLRVSAINAASEKLLTRLGVWSNIVARRASCYHGMEVWDKDSFGRITFDDASMGYS
                     HLGHIVENSVIHYALWQKAQQAADITLMAPAELQQVAWGENDAFLTLKDGAMLTARLV
                     IAADGANSWLRNKADIPLTFWDYRHHALVATIRTEEPHGAVARQVFHGEGILAFLPLS
                     DPHLCSIVWSLSPQDAERMQQSGDEAFNQALTIAFDNRLGLCRLESERQVFPLTGRYA
                     RQFAAHRLALVGDAAHTIHPLAGQGVNLGFMDAAELVDDLCRLQRQGKDIGQHLYLRR
                     YERSRKHSAAMMLAGMQGFRDLFAGENPAKKLLRDIGLKLADTLPGVKPQLLRQAMGL
                     NDLPQWLR"
     gene            complement(6469..7647)
                     /gene="ubiH"
                     /locus_tag="OPV72_002479"
                     /gene_synonym="visB"
     CDS             complement(6469..7647)
                     /gene="ubiH"
                     /locus_tag="OPV72_002479"
                     /gene_synonym="visB"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461973.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-octaprenyl-6-methoxyphenyl hydroxylase"
                     /protein_id="HCR9914750.1"
                     /translation="MSVIIVGGGMAGATLALAISQFSHGTLPVHLIEAKAPEADGHPG
                     FDARAIALAAGTCQQLARIGVWQAISDCATAINTVHVSDRGHAGFVTLDAQDYSLAAL
                     GHVAELHDIGLRLFALLRKAPGVTLHCPERVASVSRTQQQVNVTLENGNVIAGSVLVA
                     ANGTHSALASACGVDWHQEPYEQLAVIANVATAIPHQGRAFERFTPNGPLAMLPMSHG
                     RCSLVWCHPLDQRDEVLSWSDAQFCHALQAAFGWRLGRITQAGKRSAYPLALTTAAKV
                     FTHRTVVVGNAAQTLHPIAGQGFNLGLRDVMSLAETLVAAQDAGEDIGAWHVLSRYQQ
                     RRQVDRDTTIGVTNGLVHLFANRWAPLVIGRNIGLMAMELLPPARDALAQRTLGWVAR
                     "
     gene            complement(7644..8960)
                     /gene="pepP"
                     /locus_tag="OPV72_002480"
     CDS             complement(7644..8960)
                     /gene="pepP"
                     /locus_tag="OPV72_002480"
                     /EC_number="3.4.11.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro aminopeptidase"
                     /protein_id="HCR9914751.1"
                     /translation="MTQQEYQRRRQALLAQMQPGSAALIFAAPEATRSADSEYPYRQS
                     SDFWYFTGFNEPEAVLVLIKSDDTHNHSVLFNRVRDLTAEIWFGRRLGQDAAPEKLGV
                     DRALAFSEINQQLFQLLNGLDVVYHAQGEYAYADEIVLAALEKLRKGSRQNLTAPATM
                     TDWRPIVHEMRLFKSPEEIAVLRRAGEISALAHIRAMEKCRPGMFEYQLEGEIHHEFN
                     RHGARYPSYNTIVGSGENGCILHYTENESEMRDGDLVLIDAGCEYKGYAGDITRTFPV
                     NGKFTPAQREIYDIVLESLETSLRLFRPGTSIQQVTGEVVRIMITGLVKLGILQGEVD
                     QLIAENAHRPFFMHGLSHWLGLDVHDVGVYGPDRSRILEPGMVLTVEPGLYIAPDADV
                     PEAYRGIGVRIEDDIVITETGNENLTAGVVKKADDIEALMAAARQQ"
     gene            complement(8986..9564)
                     /locus_tag="OPV72_002481"
     CDS             complement(8986..9564)
                     /locus_tag="OPV72_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708672.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YecA family protein"
                     /protein_id="HCR9914752.1"
                     /translation="MSIQNEMPGYDEMNRFLNQQGAGLTPAEMHGLISGMICGGNNDS
                     SWQPLLHDLTNEGLAFGHELAQALRKMHAATSDALEDDGFLFQLYLPEGDDVSVFDRA
                     DALAGWVNHFLLGLGVTQPKLDKVTGETGEAIDDLRNIAQLGYDESEDQEELEMSLEE
                     IIEYVRVAALLCHDTFTRQQPTAPEVRKPTLH"
     gene            9731..10060
                     /gene="zapA"
                     /locus_tag="OPV72_002482"
     CDS             9731..10060
                     /gene="zapA"
                     /locus_tag="OPV72_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HCR9914753.1"
                     /translation="MSAQPVDIQIFGRSLRVNCPPDQRDALNQAADDLNQRLQDLKVR
                     TRVTNTEQLVFIAALNISYELTQEKAKTRDYAASMEQRIRMLQQTIEQALLDQGRITE
                     KTGQNFE"
     gene            10102..10285
                     /gene="ssrS"
                     /locus_tag="OPV72_002483"
     ncRNA           10102..10285
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="OPV72_002483"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            10306..10902
                     /locus_tag="OPV72_002484"
     CDS             10306..10902
                     /locus_tag="OPV72_002484"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311809.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HCR9914754.1"
                     /translation="MTQLPELSLSRQEIRRMIRQRRRALTPEQQRRFGQQAAARMLSF
                     PPVVMAHTVAVFLSFDGELDTQPLIEQLWQAGKRVYLPVLHPFSPGNLLFLHYHPQSA
                     LVTNRLNIREPRLDVRDVLPLAKLDVLVTPLVAFDEGGQRLGMGGGFYDRTLQNWQQH
                     KILPVGYAHDCQLVEKLPVEEWDIPLPAVVTPSKIWEW"
     gene            complement(11283..12515)
                     /gene="serA"
                     /locus_tag="OPV72_002485"
     CDS             complement(11283..12515)
                     /gene="serA"
                     /locus_tag="OPV72_002485"
                     /EC_number="1.1.1.95"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HCR9914755.1"
                     /translation="MAKVSLEKDKIKFLLVEGVHQKALESLRAAGYTNIEYHKGALDA
                     EQLKASIRDAHFIGLRSRTHLTEEVINAAEKLVAIGCFCIGTNQVDLNAAAKRGIPVF
                     NAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYG
                     HIGTQLGILAESLGMHIYFYDIENKLPLGNATQVQHLSELLNMSDVVSLHVPENASTK
                     NMMGAKEIALMKPGSLLINAARGTVVDIPALCDALATKHLAGAAIDVFPTEPATNSDP
                     FTSPLCEFDNVILTPHIGGSTQEAQENIGLEVAGKLIKYSDNGSTLSAVNFPEVSLPL
                     HGGRRLMHIHENRPGVLTALNQIFAEQGVNIAAQYLQTSARMGYVVIDIEADGDVAEK
                     ALLAMKAIPGTIRARLLY"
     gene            complement(12781..13440)
                     /gene="rpiA"
                     /locus_tag="OPV72_002486"
     CDS             complement(12781..13440)
                     /gene="rpiA"
                     /locus_tag="OPV72_002486"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HCR9914756.1"
                     /translation="MTQDELKKAVGWAALQYVQPGTIVGVGTGSTAAHFIDALGTMKG
                     QIEGAVSSSDASTEKLKGLGIHVFDLNEVDSLGIYVDGADEINGHMQMIKGGGAALTR
                     EKIIASVAEKFICIADASKQVDILGKFPLPVEVIPMARSAVARQLVKLGGRPEYRQNV
                     VTDNGNVILDVYGMEILDPIALENAINAIPGVVTVGLFANRGADVALIGTPDGVKTIV
                     K"
     gene            13593..14486
                     /gene="argP"
                     /locus_tag="OPV72_002487"
     CDS             13593..14486
                     /gene="argP"
                     /locus_tag="OPV72_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator ArgP"
                     /protein_id="HCR9914757.1"
                     /translation="MKRPDYRTLQALDAVIRERGFERAAQKLCITQSAVSQRIKQLEN
                     MFGQPLLVRTVPPRPTEQGQKLLALLRQVELLEEEWLGDEQTGSTPLLLSLAVNADSL
                     ATWLLPALAPVLADSPIRLNLQVEDETRTQERLRRGEVVGAVSIQHQALPSCLVDKLG
                     ALDYLFVASKPFAERYFPNGVTRSSLLKAPAVAFDHLDDMHQAFLQQNFDLPPGSVPC
                     HIVNSSEAFVQLARQGTACCMIPHLQIEKELESGELINLTPGLLQRRMLYWHRFAPES
                     RMMRKVTDALLEYGHKVLRQD"
     gene            complement(14752..15498)
                     /locus_tag="OPV72_002488"
     CDS             complement(14752..15498)
                     /locus_tag="OPV72_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidative stress defense protein"
                     /protein_id="HCR9914758.1"
                     /translation="MKFKVMALAALVGLSAMSAQASELPEGPHIVTSGTASVDAVPDI
                     ATLAIEVNVAAKDAATAKKQADERVAQYLSFLEQNQIAKKDISAANLRTQPDYDYQNG
                     KSILKGYRAVRTVEVTLRQLDKLNSLLDGALKAGLNEIRSVSLGVAQPDAYKDKARKA
                     AIDDAIHQAQALAAGFNSKLGPVYSVRYHVSNYQPSPVVRMMKAADAAPVSAQETYEQ
                     PTIQFDDQVDVVFQLEPGTGQTSTTAASTQ"
     gene            complement(15592..16227)
                     /gene="argO"
                     /locus_tag="OPV72_002489"
     CDS             complement(15592..16227)
                     /gene="argO"
                     /locus_tag="OPV72_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine exporter ArgO"
                     /protein_id="HCR9914759.1"
                     /translation="MISYYFQGVALGAAMILPLGPQNAFVMNQGIRRQYHLMIALLCA
                     LSDLVLISAGIFGGSALLMQSPWLLALVTWGGVAFLLWYGFGALKTAMSSNLELASAE
                     VMKQGRWKIIATMLAVTWLNPHVYLDTFVVLGSLGGQLAMEPKRWFALGTISASFLWF
                     FGLALLAAWLAPRLRTAKAQRIINILVGVVMWLIAFQLAREGVAHMHALFN"
     gene            complement(16428..17288)
                     /locus_tag="OPV72_002490"
     CDS             complement(16428..17288)
                     /locus_tag="OPV72_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small-conductance mechanosensitive channel MscS"
                     /protein_id="HCR9914760.1"
                     /translation="MEDLNVVDSINGAGTWLVRNQALLLSYAVNIVAAIAIIIIGLIV
                     ARVISNTVNRLMRARHIDATVADFLSALVRYGVIAFTLIAALGRVGVQTASVIAVLGA
                     AGLAVGLALQGSLSNLAAGVLLVMFRPFRAGEYVDLGGVAGTVLNVQIFSTTMRAVDG
                     KIIVIPNGKIIAGNIINYSREPVRRNEFIIGVAYDSDIDQVKQLLTTIIESDDRILKD
                     REMTVRLNELGASSINFVVRVWSKSSDLQNVYWDVLERIKREFDAAGISFPYPQMDVN
                     FKRVKDNAAE"
BASE COUNT         4083 a         5056 c         4469 g         3894 t
ORIGIN      
        1 tactgtaata tattgaatta gtaacacttt gtagcctgaa taaggcactc acactgcatc
       61 cgacataaac aaaacgcact ttattaacaa gctgaaaagg cgccgaagcg cctttagaaa
      121 acagtcgaat cagtaaatta ctggtagtcg ctaatcggta cgcaggagca gaacaggtta
      181 cggtcgccat aaacatcatc cagacgtttc accgtcggcc agtatttgtc tgccacgcct
      241 gccgggaata cggcaacttc acggctgtac ggatgcgccc actcggcgac cagttcgctc
      301 tgaatgtgcg gcgcgttcac cagcgggtta tcttccagcg gccagacacc ggctttcacc
      361 tggtcaatct ctgcgcggat agccagcatc gcatcgataa agcgatccag ctcagcctta
      421 ccttcagatt ccgtcggctc taccatcagc gtgcccgcca ccgggaacga catggttggc
      481 gcatggaaac catagtcgat cagacgcttg gcaatatcca gctcgctgat gccggtttct
      541 tctttcaatg ggcgaatatc aagaatacat tcgtgcgcca ctcggccatc gcgaccggta
      601 tacagtaccg ggtacgcgtc tttcagacgg ctggcaatgt agttagcgtt aagaatcgcg
      661 acctgacttg cctgcttcag gccttctgcg cccatcatgc ggatgtacat ccaactaatc
      721 ggcaaaatgg aggcgctgcc gaacggcgcc gcagacaccg cgccctgacg ggtgagcatc
      781 ccttcaattt gcaccacgct atgacccggt acgaatggcg ccagatgcgc tttcacgccg
      841 atcggtccca tgcctgggcc accgccgccg tgcggaatgc agaaagtttt atgcaggtta
      901 agatgcgaaa cgtccgcgcc aataaagccc ggtgaggtaa tgccgacctg agcgttcatg
      961 ttcgcgccgt caaggtaaac ctgaccgccg aactggtgca caacttcaca cacttcacgg
     1021 atcgtttctt catagacgcc gtgggtggac ggataggtca ccatgatgca agagaggttc
     1081 gcagcatgtt gttctgcttt ggcccgcaga tcgtccaggt cgatgttgcc gttcttatca
     1141 cacgccacaa ccaccacctg cattcctgcc atatgtgcag aagcagggtt agtgccgtga
     1201 gcagaggccg gaatcaggca gatatcgcga tgcccttcgt tgcggcttcc gtgataatga
     1261 cgaatcgcca gcagccccgc gtactccccc tgcgcgccgg agttcggctg catacagacg
     1321 gcgtcgtacc cggtgagttt caccagccag tcagaaagct ggctaatcat ctgatgatat
     1381 ccttcggcct gctccggcgg gcagaacggg tgcagttcag cgaattccgg ccaggtgata
     1441 gggatcatct cggcggcggc gttcagcttc atggtgcagg aacccagcgg gatcatcgcc
     1501 tggttcagcg ccagatcttt acgctccagc gagtgcatat agcgcatcat ctcggtttcg
     1561 ctgtggtagc ggttaaatac cggatgcgtc agaatcgcat cgtcacgcag cataccttgc
     1621 tgaatggaac ggctatcaag cgccacgtct ttatccagtg tttcaatgtt cagaccgtgg
     1681 ctgtcgccca gcaaaacatt gaacaactgc gccacattct cacgggtggt ggtttcatca
     1741 agggtaatac ccaccgcgtt atgaatatcg ctgcgcagat tgatctctgc cgcttccgca
     1801 cgcgccagta ccgcagcttt atcagctact tccacacaca gcgtgtcaaa gtagtgcgca
     1861 tgacgcagct ttaagccttt ctgttgcaga ccggccgcca gaatatcggt caggcggtgg
     1921 atacgattcg caatgcgttt caggccaacc ggtccatgat aaacggcata cagactggcg
     1981 atgttagcca gcagtacctg cgaggtacaa atgttggagt tcgctttctc acggcggata
     2041 tgctgctcgc gagtctgcat cgccatgcgc agtgcggtat tgcccgccgc atcttttgag
     2101 acgccgataa tacggcctgg catggagcgt ttaaattcgt ctttggcggc aaagaacgcc
     2161 gcgtgcgggc caccgtaacc catcggtacg ccaaaacgtt gcgcagagcc gaaaacaata
     2221 tccgcgccct gtttgcccgg cgcggtaagc agcaccaacg ccataaaatc ggcggcgacg
     2281 ctgacaatca ccttacgggc tttgagttcg ctaatcagcg tgccgtagtc gtgaatttcg
     2341 cccgtggtgc ctacctgttg taacagcacg ccaaatacgt cctgatgatc cagcactttg
     2401 tccgcgtcat cgacaatcac gtcaaagcca aaggttttgg cgcgtgtacg taccacgtcc
     2461 agcgtttgcg gatggacgtc agccgccaca aagaaacggt tggcattttt cagtttgctg
     2521 acgcgctttg ccatcgccat tgcttcggcg gcagcggtgg cttcgtcaag aagagaagcc
     2581 gaagccatat ccagtccggt cagatccagc gtcacctgtt ggaagttgag cagcgcttcc
     2641 aggcgcccct gagagacttc cggctgataa ggagtgtagg cggtatacca gcctggattt
     2701 tccagcatgt tgcgcaggat aaccggcggt agctgcacgg cggtgtagcc catgccaatg
     2761 taggacgtga agcgcttgtt acgcccggcg atggctttta attccgccag tgcggcatat
     2821 tcggttgccg cctcgccaac ctgcggcgga gtcgcgagct gaatgtcttt cggcacaatc
     2881 tgacctgtca gcgcgtttaa cgactcggcg ccaaccgcat tcagcatctc ttgctgctgc
     2941 gcggcgtccg gtccgatgtg gcgttcaatg aaagcgccgc ggttttcaag ctggcttagc
     3001 gtctgtgtca tgggcgatgg ttcctgaaac gtgcagtgaa tcgtaggtgt ctctaactca
     3061 attgcccggt ggcgctgacg cttaccgggc ctacgcgtgc gaaaacgaat acgcaaaatc
     3121 attcgcgttg cagtgagtag gccggataag cattagcgcc atccggcaca acattattcg
     3181 tcttctaaca atgcctcata cgcggtggca tccagcagcg attcaagctc gctttcatcg
     3241 ctggctttga ttttaaagat ccagccaccg gcatacggtt cgctgttcac cagctccggg
     3301 gagtcgctca gcgcatcgtt taccgccacg atctcgccgc ttaccggcgc ataaatgtcg
     3361 gacgccgctt ttacggactc cgccacggcg cagtcgtcgc ccgcgcttac ggtcgcgccg
     3421 acttccggca gatcaacaaa aaccatatcg cccaacagct cctgagcgtg ttcagtaatg
     3481 ccaacggtgt aagtgccatc cgcttcttta cgcagccatt cgtgttcttt gctgtatttc
     3541 agttctgcgg gtacgttgct catcaattaa tctccaaaaa aggatgaatc acgcgacggc
     3601 tttgccgtta cgcacaaaaa caggtttagt cacttttacc ggcatttcac ggttacgaat
     3661 ttgtacaatc gccgtctcgc cgatgcccgc cggaacgcgc gccagcgcaa tgctgtagcc
     3721 caacgttggg gaaaacgtcc cgctggtgat aatgccttct tgctgattgc cctgcgcatc
     3781 ggtaaaacgc accggcagtt cattacgcaa tacgcctttc tcggtcatca ccagaccgac
     3841 aagctgctca tggccttttt cacgctgcat ctccagcgcc tcacggccaa taaagtcgcg
     3901 gtcagcaggt tcccaggcga tagtccatcc catattagcc gccagcggag agataccttc
     3961 atccatctcc tgaccgtaca ggttcatgcc tgcttccaga cgcagcgtgt cgcgcgcgcc
     4021 aagaccgcac ggcttcacgc ccgcctccac cagcgcacgc cagaaatccg ccgctttttc
     4081 attcggcatg gcgatttcat agcccgcttc gccggtataa ccggtggtgg cgataaacag
     4141 atcgcccgcc tgaacgccga agaacggctt cataccttct actgcatggc gctgttggtc
     4201 agtaaacaga gtcgccgctt tttcctgcgc attcggcccc tgtaccgcaa tcagcgacag
     4261 gtcgtcacga acggtgatgt cgatggcata aggttcagcg tgttgggtaa tccaggagag
     4321 gtctttttcg cgggtggcgg agttaacaac gagacggaag aaatcttcag tgaagtagta
     4381 gacaatcagg tcatctatca caccgcccga tgcgttaagc ataccggagt agagggcttt
     4441 acccgtcttc gttagcttcg cgacgtcgtt tgccagcaga taacgtagaa actctcgtgt
     4501 acggctacca tgaagatcga caatggtcat atgcgataca tcaaacatcc cggcatcggt
     4561 gcgcacagcg tggtgttcat caagctgaga gccgtaatgc aggggcatca tccagccatg
     4621 aaaatcgacc atgcgggcgc cgcatagcgt gtgttgttcg tacaaaggcg tctgttgggc
     4681 catcttttcc tcgttgaatt agcgggggct aacaaccatt ttcatgggaa atcttcgcca
     4741 cgaaacctgg catcgacgcc ctttttcctg cgccgacgca aacgttctct tgctcctgaa
     4801 cttaccaccg aaccaggcgc taaaccataa ggctgaattt accatcacat tagcttatga
     4861 ctaaaaaacg ctaaaatccc atcagcacaa aaaaccacta ttacgctaaa taacttccat
     4921 aaaaatgaag ctgatacgat ttatcacaac ataaattaat attaaatgcg gaaaaaatgt
     4981 cgaaaatcgc gttctccaaa aatagtggca ttagaaaata taatgcgaaa taagcggtga
     5041 aattagatta tttcaaacga ggaaagcccc ccggcgcgat agccgggaaa gcaaagtgtg
     5101 acgggtttca aactcttgct ggcgtgcagt cagacgctta acgaagccat tgcggaaggt
     5161 cgtttagccc cattgcctgg cgaagcagtt ggggtttgac gccggggagc gtgtccgcca
     5221 gtttcagtcc gatgtcgcgc agcaattttt ttgccgggtt ttcgccggca aacaggtcac
     5281 gaaaaccttg catcccggca agcatcatcg ccgcgctatg tttacggcta cgctcataac
     5341 gacggagata aagatgttgg ccaatgtctt tgccctggcg ctgaagccgg cacagatcgt
     5401 ccaccagttc ggccgcgtcc ataaaaccga ggttgacgcc ttgccctgcc agcggatgga
     5461 tggtgtgcgc ggcatcgccg accaacgcca gacgatgcgc ggcaaactgg cgagcatagc
     5521 ggcccgtcag cggaaaaacc tgccgttcgc tttccaggcg gcataagccc agccgattat
     5581 cgaaggcgat agtcaacgcc tggttaaacg cctcgtcgcc gctctgttgc atacgctccg
     5641 catcctgcgg agaaagcgac cagacaatgg aacacagatg cggatcgctt aacggcaaaa
     5701 acgccagaat accttcacca tgaaacacct ggcgagcaac cgcgccgtgc ggctcttcgg
     5761 tgcggatagt cgctaccagc gcatggtgac ggtagtccca gaaagttaag ggaatatccg
     5821 ctttgttacg cagccaggag ttggcgccat ccgcggcaat caccagacgc gcggttaaca
     5881 tcgcgccgtc ttttaaagtc aggaaggcgt cattctctcc ccaggcaacc tgctgtaact
     5941 ccgctggcgc cattaaggtg atatccgccg cttgctgcgc tttttgccac agtgcatagt
     6001 gaatgacgct gttttcaaca atatgcccca gatggctata tcccatgctt gcgtcatcaa
     6061 acgtaatacg gccaaagctg tctttatccc agacttccat accgtggtag caacttgccc
     6121 gtcgcgccac aatgtttgac catacgccaa gacgggtaag cagtttttcg ctggcggcat
     6181 taatcgccga cacccgaagc tgaggcggcg catcgttcgc caactgctgg ggaacaacgt
     6241 gatccagtac cgcaacgcgc aaaccgctcc cctgcaagcc gcaggcgaca gccagtccca
     6301 ccatgcctcc gccaactatt gctacatcaa cactttgcac tatttactcc tggaaaccgg
     6361 aacaatcaaa accgtaggcc ggataaggcg tttacgccgc catccggcat ttttacgaac
     6421 acgatgccgg atggcggcgt aaacgcctta tccggcctac agatctgctt aacgcgcaac
     6481 ccaacctaag gttcgctgtg ccagcgcatc gcgcgcaggt ggtaataatt ccatcgccat
     6541 taaaccgata ttgcgcccaa taaccagcgg cgcccaacga tttgcaaaca gatggaccag
     6601 accgttcgtt acgccaatcg tcgtatcccg gtcaacctga cgacgctgct gatagcgcga
     6661 taacacgtgc caggcgccaa tatcctcgcc cgcgtcctgt gccgcgacca gcgtttccgc
     6721 caggctcatg acatcgcgca gaccgagatt aaacccttgt ccggcgatag gatgcaacgt
     6781 ctgcgccgca ttgccgacca cgacagtccg gtgagtaaac actttcgccg ccgtagtcag
     6841 ggcaagcgga tacgcgctgc gcttacccgc ctgagtaatt cgccccagcc gccagccgaa
     6901 cgcggcctgc aacgcatgac agaactgcgc gtcggaccag ctcagcacct catcgcgctg
     6961 gtcgagcggg tgacaccaaa ccagcgaaca tcggccatgc gacatcggca acatcgccag
     7021 cgggccattg ggggtaaaac gttcaaaggc gcgtccctgg tgcgggatag cggtcgcgac
     7081 attcgctatc accgctaact gttcgtaagg ctcctgatgc cagtcaacgc cgcaggctga
     7141 tgccagcgcg gagtgggtac cgttagccgc caccagcacg ctgccagcta tcacattgcc
     7201 gttttccaga gtgacgttaa cctgctgttg ggtacgcgac acgctggcta cgcgctccgg
     7261 gcagtgcagc gtaacgcctg gcgctttacg caagagcgca aacagacgca gcccgatatc
     7321 atgcagctcc gcaacgtgac ccaacgctgc caggctgtaa tcctgcgcgt ctagagtcac
     7381 aaatccggca tgaccgcgat cgctgacgtg tacggtgttg attgccgttg cgcaatcgga
     7441 aatcgcctgc cagacgccaa ttcgcgccag ttgctggcaa gtgcccgccg ccagcgcaat
     7501 cgctctggcg tcaaagccgg gatgaccgtc ggcttcaggc gctttcgctt caatcaggtg
     7561 taccggcaac gtcccatgac tgaactgaga gatggccagc gccagcgttg cgcctgccat
     7621 gccgccgcca acgataatga cgctcattgc tgccgcgccg ccgccattaa tgcctcaatg
     7681 tcatccgcct tcttcacaac gccagcggtc aggttttcat taccggtttc ggtaatgaca
     7741 atgtcatctt caattcgaac gccaatgccg cgatacgctt ccggcacgtc ggcatccggc
     7801 gcgatataga ggcctggctc tacggtcagc accatgcccg gctccaggat gcgggagcga
     7861 tccggcccat aaacgccgac atcatgaaca tccagcccca gccagtggct caagccatgc
     7921 ataaagaaag gacgatgcgc attctcggca atcagttgat caacctctcc ttgcaaaatc
     7981 cccaacttca ccagcccggt tatcatgatg cgcactactt cgccggtcac ctgctgaata
     8041 gaggtaccag gacggaacag tcgcaggctg gtctccagcg attccagaac gatgtcataa
     8101 atttcacgct gagctggcgt aaatttcccg ttcaccggga aagtacgcgt gatgtcgccc
     8161 gcgtaacctt tatattcaca gcccgcgtcg ataagcacta aatcgccgtc gcgcatttca
     8221 ctttcgtttt cagtgtaatg caggatacag ccattttcgc cgctgccgac aatggtgtta
     8281 taggagggat agcgcgcgcc atggcgatta aattcgtggt gaatttcacc ctccagctga
     8341 tactcaaaca tccccggacg gcatttttcc atcgcgcgga tatgcgccag agcgctaatt
     8401 tccccggcgc ggcgcaggac agcaatctct tccggcgatt tgaacaggcg catctcatgg
     8461 acgatcggtc gccagtcagt catggtggcc ggcgcggtca gattctggcg ggagccttta
     8521 cgcagcttct ccagcgcagc cagaacaatc tcgtcggcat acgcatattc gccctgcgcg
     8581 tggtacacca catccagacc attaagcaac tgaaagagtt gctggttgat ttcgctaaac
     8641 gccagcgccc ggtcaacgcc cagtttttcc ggcgcggcat cctgtcctaa acggcgacca
     8701 aaccagattt ccgccgtcag gtcgcgaacg cggttgaaca aaacgctgtg gttgtgggtg
     8761 tcatcactct taatcagtac cagcacggct tccggttcgt taaaaccggt gaaataccag
     8821 aagtcgctac tctggcgata cggatattca ctgtctgcgc tgcgcgtcgc ctccggcgcg
     8881 gcaaagatca gcgcggcgct gccgggctgc atttgcgcca gtaatgcctg gcgacggcgt
     8941 tggtattcct gctgagtcat gacatggcct ccatttcgtt ttttcttagt gtagcgtcgg
     9001 tttacgcact tccggcgcgg tcggctgttg gcgcgtgaaa gtgtcatgac ataacagcgc
     9061 cgcaacacgg acatattcga tgatctcttc gagcgacatc tccagctctt cctgatcttc
     9121 gctctcatca taaccaagct gcgcaatatt acgcaggtcg tcaatcgctt cacccgtttc
     9181 gccggtgact ttatcaagtt taggctgcgt tacgccgagg ccaagcaaaa agtggttaac
     9241 ccacccggct aatgcatctg cgcgatcgaa tacgctgaca tcgtcgcctt caggcagata
     9301 aagctgaaaa agaaagccgt cgtcttccag cgcgtcgctg gtcgccgcgt gcattttgcg
     9361 cagcgcctga gcaagctcat gcccgaaggc cagaccttcg ttcgtcaggt catgcaacag
     9421 cggctgccat gagctgtcgt tgttgccgcc gcaaatcatc ccgctgatta aaccatgcat
     9481 ttcagccggg gtcagaccgg ccccttgttg attcaaaaac cggttcattt cgtcgtaacc
     9541 aggcatttcg ttctgtatag acataagcat tcgtcatcaa agggaggata ttcatgatat
     9601 gctaccactt tggaccctgg tgaaccagaa aagggcttgt atcttcacac cagggtagct
     9661 atagtgtcgc cccttcgcgg accctgggtc tggagacgaa ggcagcgcag tcaatcagca
     9721 ggaaggtggc atgtctgcac aacccgtcga tatccaaata tttggccgtt cactgcgagt
     9781 gaattgcccg cctgaccaaa gggatgcgtt gaatcaggct gcggacgatc tgaatcagcg
     9841 gttgcaagat ctgaaagttc gtactagagt cacaaatact gagcagttgg ttttcattgc
     9901 cgcattgaat atcagctatg agttaactca ggaaaaagcg aagacccgcg attacgcggc
     9961 gagcatggaa caacgtattc ggatgctaca acagaccatc gaacaggcgt tgcttgatca
    10021 aggtcgcata accgaaaaaa cgggccaaaa ctttgaataa cacttttcgc tttactatgg
    10081 taaagtgatt gtgaaaacag tatttctctg agatgtttgc aagcgggcca gtcccctgag
    10141 ccgatatttc ataccacaag aatgtggcgc tccgcggttg gtgagcatgc tcggttcgtc
    10201 cgagaagcct taaaactgtg acgacacatt caccttgaac caagggttca agggttacag
    10261 cctgcggcgg catctcggag attccccttc tgactggcga cagccatgac gcaacttccc
    10321 gaactctctt tatcacgaca agaaatccgc cgaatgattc ggcaacgtcg ccgtgcgctg
    10381 acgccagagc agcaacgccg ctttggtcaa caggccgccg cccgaatgct cagctttcct
    10441 cccgtcgtga tggcgcacac tgtcgccgtg tttctctcct ttgatggcga actcgacacc
    10501 cagccgctga tagaacagct atggcaagcg ggcaagcgcg tctaccttcc ggttcttcat
    10561 cccttcagcc ctggcaacct cctgtttctg cactatcatc cgcagagtgc gctggtgacc
    10621 aaccgcttaa atatccggga gccacggctt gatgtccgcg acgtattgcc gctggcaaag
    10681 ctggatgtgc tggtaacgcc gttagtcgcg tttgacgaag gcgggcagcg tttaggcatg
    10741 ggcggcggtt tttatgaccg cacgctacaa aactggcagc agcataagat cctacctgtg
    10801 ggctacgcgc atgattgcca gttagtagaa aaactgccgg ttgaagagtg ggatatcccg
    10861 ctgcctgcgg tggtgacgcc gtccaaaatt tgggagtggt agccgtgttt tgtcgattga
    10921 cagcgtcgct tttttgacct aaatttctcg gtgaagggtg agggaggcga acctccctcc
    10981 tgcgtactca ctgttaatat gctgggcaag cgatgattaa caggatcagc agcatgatga
    11041 cgtatctcat catcgtccct ttccttttta gagcccctgc ctcggtaggg gctttcccgt
    11101 ttcagcgcta tgctgagccc ttatcgtaaa ttccttttat tgctgtacaa cacgcaacgc
    11161 tgcctttaat taccaattgc ggcaaggctc gaaaacagaa tgtatgcgtt acacgaagag
    11221 atgttgaggc agggaaacca gagaaaggat gggcaggtca tctcctgccc atttagagga
    11281 aattagtaca gcagacgggc gcgaatggtg cccggaatcg ccttcatcgc cagcagcgct
    11341 ttctccgcca catcgccatc ggcttctata tcaattacca cataccccat tcgggcggag
    11401 gtttgcagat actgtgcggc aatgttaacg ccctgctcgg caaagatctg gttaagcgcg
    11461 gtcaatacgc ccgggcggtt ttcgtggatg tgcatcaggc gacgaccgcc gtgcagcggc
    11521 agcgacactt ccgggaagtt cacggcggac agcgtcgagc cgttatccga gtacttaatc
    11581 agttttcctg cgacttccag accgatgttt tcttgcgcct cctgcgtcga gccgccgata
    11641 tgcggcgtca ggatcacgtt atcgaattcg cacagcggag aggtaaacgg atcgctatta
    11701 gtggccggtt ccgtcgggaa gacgtcgata gccgcccccg ccagatgttt cgtcgccagc
    11761 gcgtcgcaca aagccgggat atccactacc gtaccgcgcg cggcgttaat cagcagcgaa
    11821 cccggcttca tcagggctat ctcttttgcg cccatcatgt ttttggtgga ggcgttttca
    11881 ggtacgtgca gactgaccac atcgctcata ttcagcaatt cagacaggtg ctgcacctga
    11941 gttgcattac cgagcggcag tttattttca atatcataga aatagatatg catccccagc
    12001 gattccgcca gaatgcccaa ctgcgttccg atatggccgt aaccgataat gccaagcttt
    12061 ttaccgcgtg cttcgaacga tcccgccgcc agtttattcc atacgccgcg gtgcgctttg
    12121 gcgttcgctt ccggcacgcc gcgcagcagc agcaatagct cgccaatcac cagctccgcc
    12181 acggaacggg tattcgagaa tggcgcgtta aagaccggaa taccgcgttt tgccgccgca
    12241 tttaaatcca cctggttggt gccgatgcaa aaacagccaa tcgccaccag cttctctgcg
    12301 gcgttaatca cttcttctgt cagatgagta cgggatcgca gaccgatgaa gtgggcatcg
    12361 cggatggacg ctttcaactg ttcagcgtcc agcgcgccct tgtgatattc aatgttggtg
    12421 taacctgccg cacgaaggct ttccagcgcc ttttgatgca ccccttcaac cagcagaaat
    12481 ttaattttat ctttctccag cgataccttt gccatttccc cgatcctgtc tttttttgcc
    12541 atctgatgtt gtgtgtggat ttgcatccgt ccttcaacat atcaaaaaaa attatcacgg
    12601 caatatgaac gtttgcgcca acgccgtgaa ggaatcgcat acagcgggaa atagcagatg
    12661 aaaataccgg gaataacttt tctttggagg gatcggcagg gcaaacgatt aaacgtgata
    12721 catgtcacca aatttgccct gaccgaattc tttacgcggc aggaaatacg cctggcggga
    12781 tcattttacg atggttttca ccccgtccgg cgtgccgatc agtgcgacat cggcgccacg
    12841 gttggcgaac aaccctacgg tcacgacgcc cggaatcgcg ttaatggcgt tttccagcgc
    12901 gatgggatca aggatttcca taccataaac atccagaatc acgttgccgt tatccgtgac
    12961 cacgttctga cggtactccg gacgcccgcc cagcttcacc agttgacgag caaccgcgct
    13021 gcgcgccatc ggaatcactt cgaccggcaa cgggaatttg ccaagaatat ccacctgttt
    13081 agaggcatcc gcaatacaga taaatttctc cgccacggaa gcaataattt tctcacgggt
    13141 taatgccgcg ccgccgcctt tgatcatctg catatgaccg ttgatttcgt ccgcgccatc
    13201 gacatagata cccaggctat ccacttcgtt gagatcaaac acatgaatac cgaggccttt
    13261 gagtttttca gtcgaggcgt ccgagctgga gaccgcgcct tcaatctggc ctttcattgt
    13321 gcccagcgca tcaataaagt gtgcggccgt tgagcctgta ccaacgccca caatggtgcc
    13381 gggctgtaca tactgaagtg ccgcccatcc taccgctttt ttcagttcat cctgcgtcat
    13441 agatcgtttc gcctgtggtg tgaaaataca gccgcattat agaacattgt cgggaaaaat
    13501 ctccgtgtcc gtacacaggc tacggatttc atctgtaccg acggcaaatt tatgtcatag
    13561 tgcggaaaaa ataacaggag catgacacaa caatgaaacg tccggactac agaacactac
    13621 aggcgctgga tgccgttata cgtgaacgag gattcgagcg cgccgcccag aagctgtgca
    13681 tcacgcaatc cgccgtctca cagcgcataa aacagcttga gaatatgttc ggacaacctt
    13741 tgttggtgcg taccgttcct cctcgcccca cggagcaagg gcaaaaatta ctggctctgc
    13801 tgcgtcaggt tgaactgctg gaagaagagt ggctgggcga tgaacaaacc ggctctacgc
    13861 cgctactgct gtcgctggcg gttaacgccg acagtctggc gacctggctg cttccggcgc
    13921 tggcgccagt actggcggac tcccctatcc gtctcaattt acaggtggaa gatgaaacgc
    13981 gcacgcaaga acgtctgcgt cgcggcgagg tggtgggcgc ggtgagtatt cagcatcagg
    14041 cgctgcccag ttgcctggta gacaaactgg gcgcgctcga ctatctgttt gtcgcgtcaa
    14101 agccgtttgc cgagcgctat tttcccaatg gcgttacccg gtcgtcgctg ctgaaagcgc
    14161 ccgccgtcgc gttcgaccat ctggatgata tgcatcaggc ttttttgcaa cagaatttcg
    14221 atctaccgcc cggcagcgtg ccgtgccata tcgttaattc atccgaagcg tttgtacagc
    14281 ttgcgcgtca gggcacggcc tgctgcatga tccctcacct gcagattgag aaagagctgg
    14341 aaagcggcga gttgatcaac ttaacgcctg gcttgctaca acgccggatg ctttactggc
    14401 accgctttgc cccggaaagc cggatgatgc gcaaagtgac cgacgcgctg ctggagtacg
    14461 ggcacaaggt gctgcgtcag gattagcctc tctatgaatg ccggatggcg gcgtgaacgt
    14521 cttatccggc ctgcatgacc cattattccc ccgtcgcttc tttgaaattg atcacaaaat
    14581 cattgcgttc aggcggcaaa aaacgacgcg ccattggcta ttttttgctg gcggcaaggc
    14641 gactcaaaac gctcaccgta ttatcaaatc ttcatttcat tgcgtaatac ggagcaaaaa
    14701 atgagaacac cgggagaaaa cgcggcctgg aagcgcccag gccgggcgag attactgcgt
    14761 gctggcggcc gttgtcgacg tctgccctgt tccaggttca agctggaata ccacatcgac
    14821 ctgatcgtcg aactgaatag tcggctgctc gtaagtttcc tgcgcggata ccggcgcagc
    14881 atctgcggct ttcatcattc gcaccaccgg actcggctga taattagaga catggtaacg
    14941 aacgctgtaa accggcccca atttgctgtt aaaaccggct gccagcgctt gcgcctgatg
    15001 aatcgcgtca tcaatggcgg ctttgcgggc cttgtcttta taggcgtccg gttgcgccac
    15061 gcccagcgat accgaacgaa tctcgttcag acccgccttc agcgcgccgt ccagcagcga
    15121 attgagttta tctaactgac gcagcgtcac ctcaacggtt cgcaccgcgc gatacccttt
    15181 cagaatgctt ttaccgtttt ggtaatcata atccggctgc gtgcgcagat tcgccgcgct
    15241 aatgtctttt ttcgcaatct gattttgctc aaggaaggaa agatattgcg ccacgcgctc
    15301 atcggcctgc ttcttcgccg tcgccgcatc cttcgccgcg acgttcactt caatcgctaa
    15361 ggtggcgata tcaggcacag catcgacgct tgctgtaccg gaagtcacga tgtgcgggcc
    15421 ttccggcaat tcgcttgcct gcgccgacat tgcacttaaa cccactaatg ccgccagggc
    15481 catcactttg aacttcacag tctctcctcc atattgcagt cattgccctg atatacaggg
    15541 cgcatgcagg caagcttagc ggatatcggt ctgttgtcca tcagacaacg cttagttgaa
    15601 aagcgcgtgc atatgcgcga cgccttcccg cgccagttgg aaggcgataa gccacatcac
    15661 cacccctacc agaatgttga taatgcgttg agctttcgcc gtacgcagtc gaggcgcaag
    15721 ccaggccgcc agtagcgcta acccaaaaaa ccataagaac gacgcgctaa tcgtgccgag
    15781 agcaaaccag cgctttggct ccatagccag ttgtccgccg agactgccca acacgacaaa
    15841 cgtatccaga taaacgtgcg gattcagcca ggttaccgcc agcatcgtag caataatttt
    15901 ccagcgcccc tgcttcataa cctcggcgct ggccagctcc agattactgc tcattgccgt
    15961 tttcagcgcg ccaaaaccgt accataacaa gaacgcaacc ccgccccatg tgaccagcgc
    16021 cagcagccac ggcgactgca tcagcaacgc gctaccgcca aaaataccgg cgctaatcag
    16081 gactaaatca cttaacgcgc aaagcagcgc tatcatgagg tggtactggc gacgaattcc
    16141 ctgattcatc acaaacgcat tttgcgggcc aagcggaagg atcatggcgg cgccaagggc
    16201 aaccccttga aaataataag atatcacgtt aactaccctg agctgttttt cttaaaggca
    16261 gactatagcg cgggaatatt attagcggaa attgataatt ttaatcacta ataagaaaag
    16321 ctaataaaga gactgaataa cggatggcgg ctacgcttat ccgctcaata accagagaat
    16381 actggaggcg gataagcgca gcgccggcag gcagcacggg aggaaaatta ctccgcggcg
    16441 ttatctttca cgcgtttaaa attgacgtcc atctgcgggt acgggaagct aataccagcg
    16501 gcgtcgaatt cacgtttaat acgttccagc acgtcccaat agacattttg caggtcgctg
    16561 cttttactcc agacacgcac cacaaaatta attgatgagg cgcccagctc attcaaacgc
    16621 accgtcattt cgcgatcttt taaaatacga tcgtcggact cgataatcgt cgttagcagc
    16681 tgtttcacct gatcgatatc cgaatcgtag gccaccccaa taatgaattc gttacggcga
    16741 accggctcac gagaatagtt gatgatattt cccgcgataa ttttgccatt cggaatcaca
    16801 ataattttgc cgtctaccgc gcgcattgtc gtggaaaaga tttgcacgtt cagtaccgta
    16861 ccggcaacgc cgcccaaatc gacatactca ccggcgcgga acggacggaa cataaccagc
    16921 aataccccag ccgcaaggtt agaaagcgat ccctgtaatg ccaggccaac ggctaaacca
    16981 gcggcgccca gtacggcaat aaccgaggcg gtttgaaccc ccacgcgacc cagagccgca
    17041 atcagcgtaa aagcgataac cccatagcgc accagcgcag aaagaaagtc ggctactgtc
    17101 gcatcaatat gacgcgcacg catcagacga tttaccgtat tggagatcac gcgcgctaca
    17161 atcaagccga tgatgataat agcgatagcc gcaacaatat tcacagcata gctgagcaat
    17221 aacgcctggt tgcgtaccag ccaggtgccc gcaccattta tgctgtcgac aacattcaaa
    17281 tcttccattc aatattcctt ggtcatagca aaacaagcaa atgagatcat tctcacgaaa
    17341 agaacttttt aaaggtaaac aaaaacagag gaatatgcca tttttcggca tcatcccaaa
    17401 aaaggcaggt acactgtgag ttggccggat gaaagcgcta actaacgccg ctctccggaa
    17461 ataacgataa taaatatcct ccggcatagc cggaggtttt tc
//
LOCUS       DAJVBX010000088        17427 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.088, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000088 DAJVBX010000000
VERSION     DAJVBX010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 17427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17427
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.088"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            149..2140
                     /gene="cirA"
                     /locus_tag="OPV72_002491"
     CDS             149..2140
                     /gene="cirA"
                     /locus_tag="OPV72_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catecholate siderophore receptor CirA"
                     /protein_id="HCR9914761.1"
                     /translation="MFRFNPFVRVGLCMSAVTLAWPVAAATDDGETMVVTASAIEQNL
                     KDAPASISVITQQDLQRRPVQNLKDVLKEVPGVQLTNEGDNRKGVSIRGLDSSYTLIL
                     IDGKRVNSRNAVFRHNDFDLNWIPVDAIERIEVVRGPMSSLYGSDALGGVVNIITKKI
                     GQKWHGSVTVDSTIQEHRDRGDTYNGQFFTSGPLIDGVLGMKAYGSLAKREKDEQQSS
                     ATTATGETPRIEGFTSRDGNVEFAWTPNENHDVTAGYGFDRQDRDSDSLDKNRLERQN
                     YALSHNGRWDLGNSELKFYGEKVENKNPGNSSPITSESNSIDGKYVLPLASVNQFLTF
                     GGEWRHDKLSDAVSLTGGSSTKTSASQYALFLEDEWRIFEPLALTTGIRMDDHETYGD
                     HWSPRAYLVYNATDTLTVKGGWATAFKAPSLLQLSPDWATNSCRGGCRIVGSPDLKPE
                     TSESWELGLYYRGEEGILEGVEASVTTFRNDVDNRISISRTPDVNAAPGYSNFVGFET
                     NSRGQRVPVFRYYNVNKARIQGVETELKVPFNEAWKLSLNYTYNDGRDVSNGGNKPLS
                     DLPFHTANGTLDWKPAQLEDWSFYVSGNYTGRKRADSATAKTPGGYVVWDTGAAWQAT
                     KNVKLRAGVLNVGDKDLKRDDYGYTEDGRRYFMAVDYRF"
     gene            complement(2184..3506)
                     /locus_tag="OPV72_002492"
                     /pseudo
     CDS             complement(2184..3506)
                     /locus_tag="OPV72_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461143.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(3539..4426)
                     /gene="serB"
                     /locus_tag="OPV72_002493"
     CDS             complement(3539..4426)
                     /gene="serB"
                     /locus_tag="OPV72_002493"
                     /EC_number="3.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoserine phosphatase SerB"
                     /protein_id="HCR9914762.1"
                     /translation="MSIIYFITTQDIDTFQKKLQETLFNAVTMPFPLLFDKRYAALIN
                     TAYLKLTLPAECLTPEFYRYLRELSLQWQFDFFIKPQPLPANGIIAFDMDSTFIAEEG
                     VDEIARELGMSTQITAITQQAMEGKLDFNASFTRRIGMLKGTPKAVLNAVCDRMTLSP
                     GLLTILPVIKAKGFKTAIISGGLDIFTQRLKARYQLDYAFSNTVEIRDNVLTDNITLP
                     IMNAANKKQTLVDLAARLNIATENIIACGDGANDLPMLEHAGTGIAWKAKPVVREKIH
                     HQINYHGFELLLFLIEDEL"
     gene            4643..6010
                     /locus_tag="OPV72_002494"
     CDS             4643..6010
                     /locus_tag="OPV72_002494"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HCR9914763.1"
                     /translation="MESCLDIFKIVIGPSSSRTVGPMRAACHFISLLREQETLPLIRE
                     IEIELYGALSLSRKCHNVDTALYLGLLGCQPENVDLRSHMAVIKRAENENKIELPLSD
                     AGGITIKVKIIANHQAHPGHPYAMTFCARDDYFTVYEETWFSTGAGQVRKHGEPLTPS
                     LPLRTVSPFEFSHAAQLLALCRRNGLSVAALMMKNELCRHSPQTLQNYLAQIWDVMQQ
                     AVYRGLHTEGVLPGPYQVPRRACALHKTLQANRSASDFLTALNWVNAFAIAVSEENAS
                     GGQIVTAPTNGACGIIPAALCWYDKFVTPLEPGALTRFFLTAAAIAMLFKQNASILGS
                     EVGCQGEIGVACSMAAAGLAELMGASVEQTLSAAEIAMEHHLGLTCDPLGGQVQIPCI
                     ERNAISAVKAINAATMAMSRVSEPCISLDEIIAAMYETGKDMSAKYRETYHGSLGKIQ
                     PRKRG"
     gene            6015..6404
                     /locus_tag="OPV72_002495"
     CDS             6015..6404
                     /locus_tag="OPV72_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCR9914764.1"
                     /translation="MKYNTMNNDEIILSLCARLKETRLSLAMTQQQLADRAHVGIATI
                     KRIEKGGGLNLDTLISLLRALDKLHNLDAVLFESELRNFHESYEGGEGSGRLQVRQQA
                     ADLNNKSSAPQSEEVNYSAALENSLCW"
     gene            complement(6393..7250)
                     /gene="fghA"
                     /locus_tag="OPV72_002496"
     CDS             complement(6393..7250)
                     /gene="fghA"
                     /locus_tag="OPV72_002496"
                     /EC_number="3.1.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461139.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-formylglutathione hydrolase"
                     /protein_id="HCR9914765.1"
                     /translation="MEMLEEHRCFGGWQQRWRHHAATLNCAMTFSIFLPPTQDNEPPP
                     VLYWLSGLTCNDENFTTKAGAQRIAAELGIVLVMPDTSPRGEQVADDSGYDLGHGAGF
                     YLNATQPPWASHYRMYDYLRDELPALIQTQFNVSDRCAISGHSMGGHGALIMALKNPG
                     KYTSISAFAPIVNPSRVPWGIKALTAYLGEDESAWTEWDSCELMLASQPQDAIPVLID
                     QGDSDQFLADQLQPAVLAEAARQTAWPMTLRIQPGYDHSYYFIASFIEDHLRFHARYL
                     RDEHETSPT"
     gene            7580..8248
                     /gene="folE"
                     /locus_tag="OPV72_002497"
     CDS             7580..8248
                     /gene="folE"
                     /locus_tag="OPV72_002497"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HCR9914766.1"
                     /translation="MPSLSKEAALVHDALVARGLETPLRPPMDELDNETRKSLIAGHM
                     TEIMQLLNLDLSDDSLMETPHRIAKMYVDEIFAGLDYANFPKITLIENKMKVDEMVTV
                     RDITLTSTCEHHFVTIDGKATVAYIPKDSVIGLSKINRIVQFFAQRPQVQERLTQQIL
                     TALQTLLGTNNVAVSIDAVHYCVKARGIRDATSATTTTSLGGLFKSSQNTRQEFLRAV
                     RHHP"
     gene            8263..9405
                     /locus_tag="OPV72_002498"
     CDS             8263..9405
                     /locus_tag="OPV72_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF418 family protein"
                     /protein_id="HCR9914767.1"
                     /translation="MERNVTLDFVRGVAILGILLLNISAFGLPKAAYLNPAWYGAIVP
                     EDAWSWAILDIVAQAKFLTLFALLFGAGLQMLLPRGKQWIQSRLTLLVLLGFIHALFF
                     WDGDILLAYGLVGLICWRLVRDAPSVKSLFNTGILLYLVGIGVLLLLGVVSSSETSRA
                     WTPDASAILYEKYWKLNGGMEAISNRAEMLSNSLLALGAQYGWQLAGMILLGAALMRS
                     GWLKGQYSLRHYRRTGVLLVALGLMINLPAVILQWRLDWAYRWCAFLLQAPRELSAPL
                     QTLGYAALMFGFWPQLSRCRLTLAIACVGRMALTNYLLQTIICTTLFYQFGLFMKFNR
                     LELLFFVVPVWAINLLFSVIWLRFWRQGPVEWLWRQLTLRASGSLR"
     gene            9555..10577
                     /gene="galS"
                     /locus_tag="OPV72_002499"
     CDS             9555..10577
                     /gene="galS"
                     /locus_tag="OPV72_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator GalS"
                     /protein_id="HCR9914768.1"
                     /translation="MITIRDVARQAGVSVATVSRVLNNSALVSPDTRDAVMQAVTLLG
                     YRPNANAQALATQVSDTIGVVVMDVSDAFFGALVKAVDLVAQQHQKYVLIGNSYHEAE
                     KERHAIEVLIRQRCNALIVHSKALTDRELSDFMDQIPGMVLINRIVPGYAHRCVCLDN
                     VSGARMATRMLLNNGHQRIGYLAFSHRIEDDAMRREGWLHALQEQGVAASESWIGTGT
                     PDMQGGESAMVELLGRNLQLTAVFAYNDNMASGALTALKDNGIAIPLHLSVIGFDDIP
                     IARYTDPQLTTVRYPIASMAKIATELALQGAAGTLDITATHCFMPTLVRRHSVAWRQN
                     AVLITN"
     gene            11076..12074
                     /gene="mglB"
                     /locus_tag="OPV72_002500"
     CDS             11076..12074
                     /gene="mglB"
                     /locus_tag="OPV72_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/glucose ABC transporter
                     substrate-binding protein MglB"
                     /protein_id="HCR9914769.1"
                     /translation="MNKKVLTLSAVMASLLFGAHAHAADTRIGVTIYKYDDNFMSVVR
                     KVIEKDGKSAPDVQLLMNDSQNDQSKQNDQIDVLLAKGVKALAINLVDPAAAGTVIEK
                     ARGQNVPVVFFNKEPSRKALDSYDKAYYVGTDSKESGVIQGDLIAKHWQANQGWDLNK
                     DGKIQYVLLKGEPGHPDAEARTTYVVKELNDKGIQTEQLALDTAVWDTAQAKDKMDAW
                     LSGPNANKIEVVIANNDAMAMGAVEALKAHNKSSIPVFGVDALPEALALVKSGAMAGT
                     VLNDANNQAKATFDLAKNLAEGKGAADGTSWKIENKIVRVPYVGVDKDNLSEFTQK"
     gene            12208..13726
                     /gene="mglA"
                     /locus_tag="OPV72_002501"
                     /pseudo
     CDS             12208..13726
                     /gene="mglA"
                     /locus_tag="OPV72_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020883197.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/methyl galactoside ABC transporter
                     ATP-binding protein MglA"
     gene            13742..14752
                     /gene="mglC"
                     /locus_tag="OPV72_002502"
     CDS             13742..14752
                     /gene="mglC"
                     /locus_tag="OPV72_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/methyl galactoside ABC transporter
                     permease MglC"
                     /protein_id="HCR9914770.1"
                     /translation="MSALNKKSFLTWLKEGGIYVVLLVLLAIIIFQDPTFLSLLNLSN
                     ILTQSSVRIIIALGVAGLIVTQGTDLSAGRQVGLAAVVAATLLQSMENANKVFPEMAT
                     MPIALVILIVCAIGAVIGLVNGIIIAYLNVTPFITTLGTMIIVYGINSLYYDFVGASP
                     ISGFDSGFSTFAQGFVAMGSFRLSYITFYALIAVVFVWVLWNKTRFGKNIFAIGGNPE
                     AAKVSGVNVALNLLMIYALSGVFYAFGGLLEAGRIGSATNNLGFMYELDAIAACVVGG
                     VSFSGGVGTVFGVVTGVIIFTVINYGLTYIGVNPYWQYIIKGGIIIFAVALDSLKYAR
                     KK"
     gene            complement(14827..16061)
                     /gene="preA"
                     /locus_tag="OPV72_002503"
                     /pseudo
     CDS             complement(14827..16061)
                     /gene="preA"
                     /locus_tag="OPV72_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461132.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent dihydropyrimidine dehydrogenase
                     subunit PreA"
     gene            complement(16055..17296)
                     /locus_tag="OPV72_002504"
     CDS             complement(16055..17296)
                     /locus_tag="OPV72_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HCR9914771.1"
                     /translation="MPQQNYLDELTPGFTPLLAIKEASRCLLCHDAPCSQACPAQTDP
                     GKFIRSIYFRNFKGAAETIRENNALGAVCARVCPTEKLCQRGCTRSGIDKPIDIARLQ
                     RFITDFEQQTAMQIYQPGSKTRGKVAIIGAGPAGLQASVTLTHLGYDVTIYEKQPQPG
                     GWLRHGIPAFRLPQSVLDQEIARIVEMGVNIKCNCDVGGSLSLAQLKAEYRAVLMTVG
                     MSCGSDLPLFEQASHVEIAVDFLQRARQADGDISVPRSALIIGGGDVAMDVASTLKIL
                     GCPSVTCVAREELAEFPASEKEFTSTQALGVSIIDGFTPVAVSGNKVTFHHVRHSGEL
                     TLEAENIILAVGQHARLDNFAEIKAQHNIIDTHNYQTDDPAIFAAGDIVKGDKTVVYA
                     VKTGKEAAQAIHHYLEEACSC"
BASE COUNT         4256 a         4310 c         4648 g         4213 t
ORIGIN      
        1 gatgaagatt cgggcgcgac cgtcactcat gagcccgact cgcctgcata aaaagagttc
       61 gccgtgataa ccgttatcgc aggcgaaacg taatgcgttg tgagcgataa ccgatttttt
      121 tgtcgtattt acctcatgga gaaatggaat gtttaggttt aaccctttcg ttcgggtagg
      181 gctttgtatg tccgcagtta cgttggcctg gccggttgcc gcggcaacgg atgatggtga
      241 aaccatggtc gttaccgcgt ccgccatcga acaaaatctg aaagatgcgc cagcaagtat
      301 cagcgtcatt acccagcaag atttacagcg caggcccgtg caaaacctga aagatgtcct
      361 gaaagaggtg ccgggcgtac agctcactaa cgaaggggat aaccgtaaag gcgtgagtat
      421 tcgtggtctg gacagcagtt atacgctgat cctgatcgac ggtaagcgcg ttaactcccg
      481 taacgcggtc ttccgccata atgattttga tctgaactgg ataccggttg acgctatcga
      541 acgcattgaa gtggtgcgtg gccccatgtc ctcgctgtat ggctccgatg cgctgggcgg
      601 cgtggtcaac attatcacca aaaaaattgg tcagaaatgg cacggcagcg tcacggttga
      661 ctccactatt caggaacatc gcgaccgtgg cgatacctat aacggtcagt tctttaccag
      721 cggtccgctg atcgacggcg tgctgggaat gaaagcctac ggtagcctgg cgaaacgcga
      781 aaaagacgag cagcagagtt ccgccaccac cgctacgggt gaaacgccgc gcattgaagg
      841 atttaccagc cgggatggaa acgtcgagtt tgcctggaca ccaaacgaaa atcatgacgt
      901 taccgcaggc tacggttttg atcgccagga ccgggactcc gactcgctgg ataaaaaccg
      961 actggaacgg caaaactacg cgttgagcca taacggacgt tgggatctcg gcaatagcga
     1021 gctcaagttc tacggcgaaa aggtggaaaa caaaaacccc ggcaacagta gccctatcac
     1081 gtcagaaagc aattcgattg acgggaaata cgttctgccg ttagcgtctg tcaaccagtt
     1141 cctcaccttc ggcggcgaat ggcgtcacga taaactgagt gatgcggtga gcctgaccgg
     1201 cggttccagt actaaaacct ccgccagcca gtacgctctg ttccttgaag atgagtggcg
     1261 catcttcgaa ccgctggcgc tgaccaccgg tattcgtatg gatgaccatg aaacctatgg
     1321 cgatcactgg agcccgcgtg cttatctggt ctataacgca acggataccc tgacggtgaa
     1381 aggtgggtgg gccacggcct ttaaagcgcc gtcgctattg caattaagtc cggactgggc
     1441 gaccaactcc tgccgtggcg gatgccgcat tgtcggtagc ccggatctga aacctgaaac
     1501 tagtgaaagc tgggagctcg gcctttatta ccggggcgaa gaaggcatac tggagggcgt
     1561 ggaagcgagc gttaccacgt tccgtaacga tgtggacaat cgcatcagca ttagccgtac
     1621 ccctgacgtt aacgccgcgc ccggctattc caactttgtc ggcttcgaaa ccaacagtcg
     1681 gggacagcgc gttccggtct tccgttatta caacgtgaat aaagcacgta ttcagggtgt
     1741 ggaaaccgag ttgaaagttc cgtttaacga ggcgtggaaa ctgtcgttga attacaccta
     1801 taacgacgga cgcgatgtca gtaatggcgg gaacaagccg ctttccgatc tgccgttcca
     1861 caccgcgaac ggtacgcttg actggaaacc ggcgcagctt gaagactggt cattctacgt
     1921 atcagggaat tataccggac gtaagcgggc cgacagcgca acggcgaaaa cgccgggcgg
     1981 gtacgtggtc tgggataccg gcgcggcatg gcaggcgacg aaaaacgtta aactgcgtgc
     2041 gggcgttctg aacgtgggcg ataaagatct caaacgcgac gactacggtt ataccgaaga
     2101 cggacgtcgt tactttatgg cggtggatta ccgtttctga cagagactgg cgacagccgc
     2161 gttttgccgc tgtcgccaga atgttataac cgatgcagcc tggagagcag cgccagcgac
     2221 agagtcgtta gcagaatggc gattaacgca tagatataaa cgcccgacca cgcccagcta
     2281 tttttcacca taattaccgg cacaccggcc attgccgcgc cgacatagct gaacaatccc
     2341 cgaaagccgg taatcgatcc cgccgcatcc ttatgggtca catccagaca gccgacggca
     2401 aaaagcatat gcggtccgta taaggcgaag cccatgatgg tgaacagaat cgcgctgagg
     2461 gtgtaagagg tatcctgaac cagcggcacc agcacgatgc atatgcacag cgctaacgcg
     2521 aagattaacc cggtcatcca gcggttactt ttgaacataa agtcagacaa gtagcctgcc
     2581 agcaacccac ctgccagtcc gcccgcctca aatcaggaaa taatcgagtt cgcttttatc
     2641 agactccagc cgtgaacctg cgaatagtaa atctgcggcc agtcgttaag aatagtgcgc
     2701 gcaatataaa ccgacatatc accgataata atgatccata ccagtggatt ggtcaggata
     2761 tatttcacaa aaatctgcca gaagctcagg ttgaccgggc tggccttgac ctgggccagt
     2821 tccgtcgggt cgttacgcca ctgccccacg ttgggcaaac ctaacgtacc gggacgatct
     2881 ttaatggtaa atagcgccac tatccccatc agcagcgaaa tggcgccggg aacataaaat
     2941 cccattttcc agctaccgct aaaggcgata gcaaaactgg tcagcagcgg cgcgaggctg
     3001 ccgccgatat tgtgcgccgc ttcaacgata gcccaccagc gtccccgttc gtttttcgaa
     3061 aaccacgagg ccataatttt cgccatcggc ggaaagctgg tgccctgtaa tatcgcgttg
     3121 agactgtaca gcacgtagaa tgccgccacg ctgtcggaaa agccgaacag aatatttaca
     3181 atccccacgc caatcagcac cgggccggtc atggctttcg ggttaatttt atcgaccagc
     3241 atcccgccga caaacttcat cgcgccataa agaatgtaaa aaatagaaga cataatggcg
     3301 aagtcttctg cggtcagcga cgtttccgtc agcatggccg gcatcgcggc ggagaagttt
     3361 ttacgggtaa gataaaagac ggcataagag ataaagaccg aggcgataat ctcaaaacga
     3421 aattttttat aggtctggtc tatctctttt ttctctttta caatcggctt atcgggctgg
     3481 ctgaaaataa atgtttttat actcatttta aaattccctt ccggcgaggt gagtcgcgtt
     3541 ataattcatc ttcaataaga aaaagaagca attcgaaacc gtgataatta atctgatggt
     3601 ggattttttc ccgtacaacc ggcttcgctt tccaggcaat accggtgcca gcatgttcta
     3661 acatcggcag atcgttggcg ccatcaccgc aggcaataat attctccgtg gcaatattta
     3721 accgggcagc caggtcaacc agcgtctgtt ttttgtttgc ggcgttcata atcggcaagg
     3781 taatgttatc cgtcagaacg ttatcgcgta tttcaaccgt attcgaaaag gcataatcca
     3841 gttgataccg cgcttttaga cgctgggtga atatatccag tcccccggag ataatcgcgg
     3901 ttttaaatcc tttggccttg atgactggca gaatagttaa caggcctggc gaaagggtca
     3961 tgcgatcgca tacggcgttc agcactgctt tcggtgtgcc tttcaacatt ccgatacgtc
     4021 gggtaaaact ggcgttaaaa tcaagcttgc cctccatcgc ctgttgggta atggcggtga
     4081 tttgcgtcga catgccaagc tcgcgggcaa tttcatccac gccttcttcc gcaataaatg
     4141 tcgagtccat atcaaacgcg ataataccgt tagcaggcag tggctgcggc ttaataaaaa
     4201 aatcaaactg ccattgcaat gagagttcgc gtaaatagcg ataaaattca ggcgtcagac
     4261 attccgctgg cagcgtaagc tttaaataag cggtattgat aagcgcggca taacgtttat
     4321 caaataatag cggaaacggc atggtgacgg cattaaataa cgtttcctgt aattttttct
     4381 gaaacgtatc gatatcctgt gtagtaataa aataaataat gctcatatga taactccctt
     4441 aatttacggg tattataatg gctcttttgc ggcgtggaat ctcgtgctat cacagatatc
     4501 acagccagaa aagggctaaa aaagcgttgt ttttgatacc aggtaaagtt cagacacaaa
     4561 aggtatcact tttgatatgc caactgtgcg aggatgttat ttattactga acgcgaatga
     4621 gactgaaagg attgatataa cgatggagag ttgccttgat atattcaaaa tagtaatagg
     4681 tccatccagc tcacgtaccg tagggccgat gcgcgccgcc tgtcacttta tttcattgct
     4741 cagagaacaa gagacgttgc cgctaattcg ggaaattgaa atcgagctgt atggcgcgtt
     4801 atcgttaagc cgcaagtgcc acaatgtgga taccgccctg tatcttgggc tgctgggttg
     4861 ccagccggag aatgtcgatc tccgttcgca tatggcggtg attaagcgtg cggaaaatga
     4921 aaacaaaatc gaactcccgc tctctgacgc gggcggaatc acgataaaag tcaagattat
     4981 cgccaatcac caggcgcatc caggccatcc ttatgccatg acgttttgcg ccagggatga
     5041 ttattttacg gtgtatgaag agacctggtt ttctaccggc gccgggcagg ttcgtaaaca
     5101 tggcgagccg ctgacgccat cgcttccttt gcgtacagtg tcgccctttg aatttagtca
     5161 tgccgcgcag ttgctggcgc tgtgtcggcg taacggcctg tccgtggcgg cgctgatgat
     5221 gaaaaatgag ctgtgccgcc actcgccaca gacgttgcag aattatctgg cgcaaatatg
     5281 ggacgtgatg cagcaggcgg tttatcgcgg cctgcatact gagggggtat tacccggtcc
     5341 ctatcaggta ccgcggcgcg cctgtgcgtt acataagacg ttacaggcta accgctccgc
     5401 cagcgatttt ttaaccgcgc tgaactgggt caatgccttc gcgattgcgg taagcgaaga
     5461 aaatgccagc ggcggacaga ttgttaccgc gccaaccaat ggcgcgtgcg gcatcattcc
     5521 ggcagcgctc tgctggtatg ataaatttgt cacgccgctg gagcccggtg ctctgacccg
     5581 tttcttcctg accgccgccg ctatcgcgat gctgtttaaa caaaacgcct ctattctggg
     5641 atctgaagtt ggctgtcagg gggaaatcgg cgtggcgtgc tcaatggcgg cggcgggcct
     5701 ggctgaactg atgggtgcat ccgtggagca aacgctgagc gccgctgaaa ttgccatgga
     5761 acatcatctg ggattgacct gcgatccgct gggcgggcag gtacaaattc cctgcataga
     5821 gagaaatgcc atctctgccg tgaaagcgat aaacgcggcg acgatggcga tgagtcgcgt
     5881 aagcgaaccc tgtatttcgc tcgatgagat cattgctgcg atgtacgaga ccggtaaaga
     5941 catgagcgct aaataccgtg aaacgtatca tggttcgctg gggaaaattc agccgcgcaa
     6001 gagagggtaa cagcgtgaaa tacaatacga tgaataacga tgagattatc ctgtcgttgt
     6061 gcgcccgctt aaaggagacg cgtctgtctc ttgcgatgac ccagcagcag cttgccgatc
     6121 gcgcgcacgt tggcattgcc accatcaagc gtatcgagaa ggggggaggg ctcaatcttg
     6181 atacgctaat ttctctcctg cgggcgctgg ataagttgca taatcttgat gcggtgctgt
     6241 ttgaatccga actgcgtaat tttcacgaaa gttatgaagg cggagagggc agcggccgcc
     6301 ttcaggtacg ccagcaggcc gcggatttaa ataataaatc ttccgcgccg cagtcggagg
     6361 aggtgaacta cagcgcggcg ctggaaaatt cattatgttg gtgacgtctc atgctcgtcc
     6421 cgtaaatacc gggcatgaaa gcgcagatgg tcctcaatga aggacgcaat aaaataatag
     6481 ctatgatcgt aaccgggctg gattcgtagc gtcatcggcc aggcggtttg ccgcgcggct
     6541 tccgccagta cggcgggctg aagctgatcg gcgaggaatt gatcgctgtc accctgatcg
     6601 atgagcacag gaatggcgtc ctgcggctgg ctggccagca ttaattcgca gctatcccac
     6661 tcagtccagg ctgattcatc ttcgccgaga taagcggtaa gcgctttgat tccccacggc
     6721 acgcggctgg ggttgacgat gggcgcaaaa gcagagatgc tggtgtattt gcccggattt
     6781 ttcagcgcca tgattaacgc gccgtggccg cccatcgagt gcccgctgat ggcgcaacgg
     6841 tcgctgacgt taaactgtgt ctggataagc gccggaagct catcgcgcag gtaatcgtac
     6901 atgcgataat ggctggccca gggcggctgt gtggcattga gataaaaccc ggcgccgtgg
     6961 cctaaatcgt atccgctatc gtcggcgacc tgttcaccgc gtggactggt atccggcatc
     7021 accaatacaa tgcccagttc tgctgcgata cgctgcgcgc ctgctttggt ggtaaaattc
     7081 tcatcattgc aggtcaaccc ggacaaccag tacagtaccg gaggcggttc attatcctga
     7141 gtcggcggaa gaaaaatgct gaatgtcatg gcgcagttta gcgtggcggc atgatgacgc
     7201 cagcgctgct gccagccgcc aaaacatcgg tgctcttcga gcatttccat gcgggggctc
     7261 cttttatagt gaacctgata aggtatgcag attcttcata atacagatta ttcaccgcgt
     7321 tgtgagtaac tttcacttcc gtaatacata aacatgcttc atcatttaaa taacgttgcg
     7381 ttaacaaata tgccctttgt cctgccagca ttctcgcacc ggaaaagatg tcatgaaagg
     7441 cagcgacaat ttcaacaatt atgggcgtga atactggatt atgtgcgcta cctcacgcac
     7501 aataatcaca ctgtcacaat attgacaaac tttgccccat gcagggcaga ggcgccacac
     7561 ctgcaggaga acacgattaa tgccatcact cagtaaagaa gcggccctgg ttcatgacgc
     7621 gctggttgcc cgggggctgg aaacgccgct gcgcccgcct atggatgaac tggataatga
     7681 aacgcgaaaa agccttatcg cagggcatat gactgagatt atgcagttgc tgaatctcga
     7741 tttgagcgat gacagtctga tggaaacgcc gcatcgtatc gctaagatgt acgttgacga
     7801 gatttttgct ggcctcgact atgctaattt cccgaaaatt accctcattg aaaataaaat
     7861 gaaggtggat gaaatggtca ccgtccgcga tatcacgctg accagcacct gtgaacatca
     7921 cttcgtgacc attgatggca aagcgaccgt cgcgtatatc cccaaagatt ccgtgatcgg
     7981 cctgtcgaaa attaaccgca tcgtgcaatt cttcgcccag cgtccgcagg ttcaggaacg
     8041 tttgacccaa caaattctga cggcgctgca aaccttgctc ggcaccaata atgtagcggt
     8101 atcgattgat gcggtgcatt actgcgtgaa agcgcgcggt attcgtgacg caaccagcgc
     8161 cacgacgacg acgtcgctgg gcggattgtt taagtccagc cagaatacgc gccaggagtt
     8221 tctgcgtgcc gttcgccatc atccatgatt aaggcggaga cgatggagcg taatgtcacg
     8281 ctggattttg tacgtggcgt cgctatcctc ggtatcctgc ttcttaacat tagcgccttt
     8341 ggattgccga aggcggctta tctcaatccc gcctggtacg gcgcgatcgt tcccgaagac
     8401 gcctggtcct gggcgattct cgatattgtg gcgcaggcta agtttcttac gctgttcgcg
     8461 ttgttgtttg gcgcggggct acaaatgctg cttccgcgtg gtaaacagtg gattcagtcg
     8521 cgcttaacgc tattggtact gttaggtttt atccatgcgt tattcttttg ggacggcgac
     8581 attctgctgg cctacggtct ggtcggatta atttgctggc gactggtacg cgacgcgcct
     8641 tcggtaaaaa gcctgttcaa taccggcata ctcctttatc tggtcgggat tggcgtacta
     8701 ctgctgctgg gtgtggtatc gagtagcgaa accagccgcg cctggacgcc ggatgcgtcg
     8761 gcaatattgt atgaaaaata ctggaagctg aacggcggca tggaggctat cagcaaccgg
     8821 gcagagatgc tgtcaaatag tttactggcg ctcggcgcgc agtatggctg gcaactggca
     8881 ggtatgatac tgctgggcgc cgcgctaatg cgtagcggct ggctgaaagg ccagtacagt
     8941 ctgcggcact atcgccgtac cggggttctg ctggtggcgt tagggctaat gatcaacctg
     9001 cctgcggtca ttttacaatg gcggctggac tgggcgtacc gctggtgcgc cttcttattg
     9061 caggcgccgc gcgaactgag cgcgccgttg caaacgctgg gctatgccgc gctgatgttt
     9121 ggcttctggc cgcagcttag ccgatgcaga ctgacgcttg ccattgcctg cgtagggcga
     9181 atggcgctga ccaattattt gctgcagacg atcatctgta ccacgctgtt ttatcagttt
     9241 ggcttattta tgaaattcaa tcgactggaa ctcttgttct ttgtcgttcc ggtatgggca
     9301 ataaaccttc tcttttccgt catctggcta cgtttctggc gacagggacc ggtcgagtgg
     9361 ttatggcgtc aactcacgtt gcgcgcgtca ggatcgctca gataacgatc tggatcacat
     9421 tcattaacaa aatggctgta accgtttcca tccctgtgat gtttctcacg cagccctggg
     9481 cagggtgctg acaaaatagc cgcctgctaa cggggcattt gtgagcattt ttgaactcaa
     9541 acagggcagt gaatatgatc accattcgtg atgtagcgcg ccaggctggc gtgtctgtag
     9601 cgaccgtttc ccgcgtactg aataacagcg cgttggtcag tcccgacacc cgtgacgccg
     9661 ttatgcaggc cgtcaccctg ctgggatatc ggccaaatgc gaatgcgcaa gcgctggcca
     9721 ctcaggtgag cgataccatc ggcgtcgtag tcatggatgt ttccgatgcc tttttcggcg
     9781 ctctggtgaa agccgtagat ctggtcgcgc agcagcacca gaaatatgtt ctcattggca
     9841 acagttatca tgaggcggaa aaagagcgcc atgcgattga agtcttgatc cgtcagcgtt
     9901 gtaacgcatt gattgttcac tcaaaagcct taaccgatcg cgagctgagc gactttatgg
     9961 atcagatccc cggtatggtg ctgattaacc gtatcgtgcc gggttatgcg catcgttgtg
    10021 tctgtctcga caatgtgagc ggcgccagaa tggcgacccg aatgttgctg aataatggac
    10081 atcaacgcat cggctacctg gccttcagcc accgtattga agatgacgcg atgcgcagag
    10141 aagggtggtt acacgcgctg caagagcagg gggttgctgc gtcggagagc tggattggca
    10201 ccggcacgcc ggatatgcag ggcggcgagt cggcaatggt tgagttgctg ggacgcaatc
    10261 tgcaactgac ggcggtattt gcctataacg ataacatggc gtcgggcgcg ctgacggcgt
    10321 taaaagataa cggcatcgcc attcccttgc atctgtctgt catcggtttc gatgatatcc
    10381 ctattgctcg ttataccgat cctcagttga ctaccgtgcg ctatcctatt gcttctatgg
    10441 cgaaaatcgc gaccgagctg gcgttacagg gggccgcagg cacgctggat atcacggcga
    10501 cgcactgctt catgccgacg ctggtacggc gccattcggt ggcgtggcga cagaatgcgg
    10561 tactgatcac taactgatta cgccccgcat gtaaccgttt tcaatctgtg agtaaattca
    10621 cagtttatta acattgtgat agctatgatg acaacgtttg tcgcactgta actaatgtgt
    10681 aacagttagt tgttagtttt gctggggtat ttcgcttata aaaaccatta tcacaatatc
    10741 ccgcgactac cggacaaaaa taaagagttg aataagagct tatcccatta gggctatttt
    10801 acttgccatt ttggacctgg gcagtgctcg ccaaaacgcg ttagcgtttt gaacgccgct
    10861 agcagcggcc cgaagggcga gcgtagcgag tcaaacctca cgtactacgt gtacgctccg
    10921 gtttttgcgc gctgtccgtg tccaaactgg ctgcgccaat aacgcctggt gggataggct
    10981 ctaaatacgc ttcggcgttc agtaacatgc gttaacgtgc tgaacagccg ggcatttttt
    11041 tacgctatac cctacataat aaaaccggag ctaccatgaa taagaaggta ctgacccttt
    11101 ctgccgtgat ggcaagtctg ttattcggcg cgcacgcaca cgcggctgat actcgtattg
    11161 gcgtgacgat ttataaatat gacgataact ttatgtccgt ggtgcgtaag gttattgaaa
    11221 aagatggcaa atccgcgccg gatgttcagc tactgatgaa tgactcgcaa aacgatcaat
    11281 ctaaacagaa tgatcaaatt gacgttttat tggcgaaagg ggttaaagct ctggcgatta
    11341 acctggtcga cccggcagcc gccggtacgg tgattgagaa agcgcgcggg caaaatgtgc
    11401 cggtggtgtt ctttaacaaa gagccttccc gcaaagcgct ggacagctat gacaaggcgt
    11461 attatgtcgg gactgactct aaagaatccg gtgtgattca gggcgacttg attgccaaac
    11521 actggcaggc gaatcagggt tgggatctga ataaagacgg taaaattcag tatgttctgc
    11581 tgaaaggcga gccggggcac ccggatgctg aagcccgtac gacgtatgtg gtgaaagagt
    11641 taaatgataa aggtattcag accgagcaac tggcgttaga caccgctgtg tgggataccg
    11701 cgcaggcaaa agataagatg gatgcctggc tgtctggccc gaacgctaac aagattgagg
    11761 tggttatcgc gaataacgat gcgatggcga tgggcgcggt agaggcgctg aaagcgcata
    11821 ataaatcgtc gattccggtc tttggcgtcg atgcgttacc ggaagctttg gcgctggtga
    11881 aatcgggcgc gatggccggt acggtactga atgacgccaa caatcaggcg aaagcgacat
    11941 tcgatctggc gaaaaacctc gccgaaggca agggcgcggc tgacggcacc agctggaaga
    12001 ttgagaacaa aatcgtgcgc gtgccttatg tcggcgtgga caaagacaat ctgagcgaat
    12061 ttacccaaaa ataacttttc cgtctgtggg cgcaattttg ttgcgccctg aaaccgtgga
    12121 agggtgacgt gccgcagacc ggataacgta tttcttttgc catccggcgc ggatagtcat
    12181 aattaaaaag gccgacaggg tatcattatg ggcagcacga tctctccgtc gtcgggtgaa
    12241 tatttgttgg aaatgcgtgg cattaacaaa tcatttcccg gcgtgaaagc gcttgataat
    12301 gtcaacttaa acgttcgtcc gcactctatt catgcattaa tgggcgaaaa cggcgcaggc
    12361 aaatcaacat tattaaaatg tcttttcggt atttatcaaa aagactccgg cagcattgta
    12421 tttcagggaa aagaagtgga cttccattcg gcgaaagaag cgctggagaa tgggatttcg
    12481 atggtacacc aggagttaaa cctggtatta caacgttcgg tcatggataa catgtggctg
    12541 gggcgttatc ccaccaaagg tatgtttgtc gaccaggata aaatgtacca ggataccaaa
    12601 gcgatatttg atgagctgga tatcgatatt gacccgcgcg cgcgtgggaa cgttatccgt
    12661 ttcgcaaatg cagatgattg aaattgcgaa ggcgttttcc tataacgcta agatcgttat
    12721 tatggatgaa ccgacctcat cgttaactga gaaagaggtt aatcatctgt tcaccattat
    12781 tcgcaagctg aaagaacgcg gctgcggcat tgtttatatc tcgcataaaa tggaagaaat
    12841 ttttcaattg tgcgatgaaa ttactatctt gcgcgacggt cagtggattg ccacccagcc
    12901 gctggaaggg ctggatatgg ataagatcat tgcgatgatg gtcgggcgtt ccctgaacca
    12961 gcgctttccg gataaagaaa ataagccggg cgacgtgatt ctggaggttc gtcacctgac
    13021 ctcgctgcgc cagccttcca ttcgcgatgt ctcctttgat ttgcacaagg gcgaaattct
    13081 gggcattgcc ggtctggttg gggcaaagcg taccgatatc gtcgaaacgc tgtttggcat
    13141 tcgtgagaag tcgtccggga caatcacttt acatggcaag aaaattaata atcacactgc
    13201 gaacgaagcg attaaccacg gttttgcgct ggtgacggaa gagcgtcgtt ccaccggaat
    13261 ttacgcctat ctggatatcg gatttaactc attaatttcg aatatccgta attataaaaa
    13321 taaagtgggg ttactggata attcccggat gaaaagcgac acccaatggg tcattgattc
    13381 catgcgggta aaaacgccgg ggcatcgcgc gcaaattggt tcactttccg gcggcaatca
    13441 gcaaaaggtg atcattggtc gctggctatt aacgcagccg gaaatattaa tgctggacga
    13501 accgacccgc ggcattgatg tcggcgcaaa atttgaaatt tatcagctta ttgcggaact
    13561 ggcgaaaaaa ggcaagggga tcatcattat atcttctgaa atgccggagc tgttagggat
    13621 taccgatcgt atcctggtga tgagtaacgg tctcgtttcc ggcattgtcg atactaaaac
    13681 aacaacgcaa aacgaaattt tgcgtcttgc ttctttgcac ctttaagatc aggggctcct
    13741 tatgagtgcg ttaaacaaga aaagcttttt gacctggctg aaagagggcg gaatttacgt
    13801 cgttctttta gtgctgctgg cgattattat tttccaggac ccgacttttt taagtttgct
    13861 gaatttaagt aatattctga cgcaatcttc ggtacgtatt attatcgcgc tgggcgtggc
    13921 gggactcatc gtcacccagg ggacagacct gtcggcgggg cgtcaggtag ggctggcggc
    13981 ggttgtggcg gcaacattac tgcaatcaat ggaaaacgcc aacaaagtgt ttccggaaat
    14041 ggcgaccatg ccgattgcgc tggtcatcct gattgtctgc gcgattggcg cggtgattgg
    14101 cctggtgaac ggcatcatca ttgcttacct gaacgtgacg ccgtttatta ccacgcttgg
    14161 cacgatgatt atcgtttatg gaatcaactc cctttactat gactttgtcg gcgcttcgcc
    14221 catttccggc tttgacagcg gcttttccac ctttgcgcag ggctttgtgg cgatgggcag
    14281 tttccggctc tcctacatca ccttttacgc tctgattgcg gtagtgtttg tctgggtgct
    14341 gtggaataag acccgctttg gtaaaaacat ttttgctatt ggcggcaacc cggaagcggc
    14401 gaaagtttct ggcgtaaacg tggcgctgaa cctgctgatg atttatgcgc tctccggcgt
    14461 gttttatgcc ttcggcggct tactggaagc agggcgtatt ggttctgcca ccaacaacct
    14521 cggctttatg tatgaactgg atgcgattgc cgcgtgcgtg gtcgggggcg tatcgtttag
    14581 cggcggagtg gggacggtct tcggcgtggt gaccggcgtc attatcttta ccgtcatcaa
    14641 ctatggcctg acctatatcg gggtaaaccc gtactggcag tacattatca aaggcggcat
    14701 tatcattttc gccgtggcgc tggactcgct gaaatacgcg cgtaagaagt agttatccag
    14761 acgtattacc ttgcttatca gataacccgg cgcagcgaaa ctgcgcgccg ggcttcatac
    14821 cgtgagctac agcgttaacg cgtgttcttt ttcgcctttt ttaaatttga cctcgcctaa
    14881 atcaatacag gcgaccgggc agacatgacc gcacagcaga caaccgacgc atttttccgt
    14941 attgcaatgc ggcgtgtggc tgtgttcatc ccactccatc gcctgatgac cgccgtcata
    15001 gcaggagata tagcaacgtc cgcagccgac gcatttctcc tgattaatcc gcggatagac
    15061 gatatagctg cgatccaggt cttccgccgg gataatattg ccattcgcca gcccgatcat
    15121 ctcctgtaat gaggcaaatc cctgatcggc cagatagtgg ctgaggccgc tcgccatatc
    15181 ttctacaatg cggtaaccgt attgcataat gcctgtcgtc acctgtaggg tcgccgcgcc
    15241 cagcagcaga aattcggcag cgtcttccca ggtttcaatg ccgccgatac cgctaatcgg
    15301 gaaatcgcgc agttcagggt gcattcgcaa ctgctggata aaacgcagcg caatgggttt
    15361 caccgctttt cctgaataac cggagatgct ggatttaccg ttaaccaccg gcatcccgat
    15421 tttgcggttc aggtcgatgt tagtaatgga tttcacggtg ttgatggtgg cgataccgtc
    15481 ggccccgccg cgtttggcgg ccagcgcgac ttcacacata tcgccaatat tcggcgtcat
    15541 tttcgccagc attggcaaag atgaaccgcg ttttacggcg cggcagtatt tttcaaccag
    15601 ttccgggctt tgccctacat cgcttcccat ggcgtgcgag gtcatctgcg ggcaagagaa
    15661 gttacactca atcatatccg cgccggcttc ttcaaccaga cgcgccagtt cctgccactg
    15721 ctgctcattt tcccccatga tggaagcaat cagcacctta tccggataat cctgttttag
    15781 ccgtcgaatg gcggccagat tctcttccag cggatgctca gcaatttgct ccatgttttt
    15841 gaaaccaata aaaccggtat cttctttcgt caggtggtca aaacgtggag agacttcgtt
    15901 ggcaataaaa aaccaatggt tttaaaaacg atcccgcccc agccggtatc ataggctttg
    15961 gcgcacatct cataacaatt gcctaccgga gaagaagaaa ggcaaaacgg attgggaaac
    16021 ttaacgccgc aaaaggtaac agacaaatct tttgttaaca tgagcaggcc tcctctaaat
    16081 aatgatgaat agcctgagcg gcttcttttc cggtttttac cgcataaacg acggtcttat
    16141 cacctttaac aatatcgcca gcggcaaaga tcgccgggtc gtcggtttga taattgtgcg
    16201 tgtcgataat attatgctgc gcttttatct ccgcaaagtt atccagtcgc gcgtgctgcc
    16261 ccacggccaa aataatattt tccgcttcca gcgtcagttc tcctgagtgg cgtacatggt
    16321 ggaaggtcac tttatttccg ctgacggcga caggcgtaaa accatcaata atcgatacgc
    16381 ctaatgcctg cgtgctggta aattcttttt cgctggcggg gaattcggct aattcttccc
    16441 gcgccacgca ggtgacggaa ggacagccga gaatttttaa cgtactggcg acatccatcg
    16501 ctacgtcgcc gccgccaata attaatgcgc tacgcggaac gctaatatcg ccgtcggcct
    16561 gacgggcgcg ctgtaaaaaa tcaacggcaa tctctacgtg actggcttgc tcaaataacg
    16621 gtaaatcaga gccacaggac atcccgacgg tcatcagcac ggcgcgatat tcggctttga
    16681 gttgcgcaag cgatagcgac ccgcccacgt cacaattaca tttaatattg acgcccattt
    16741 ctacaatgcg ggcaatttcc tgatcgagta cgctttgcgg cagacgaaat gccgggatgc
    16801 cgtgacgcag ccatccgccg ggctgcggct gtttttcgta aatggtgacg tcatagccta
    16861 aatgtgtgag cgtcacgctt gcctgcaaac ctgccggacc cgcgccaata atcgcgactt
    16921 tcccgcgtgt tttactcccg ggctgataaa tctgcatggc agtctgctgt tcaaaatcgg
    16981 taataaaacg ttgcaggcgt gcaatatcaa taggtttatc tattccggaa cgtgtacatc
    17041 cgcgctggca taatttttcc gtcggacaga ctctggcgca gacggcgcca agcgcattat
    17101 tttcccggat agtttccgct gcgcctttaa aattgcgaaa gtaaatagaa cgaataaatt
    17161 tccccggatc ggtttgcgcc gggcaagcct gactacaggg cgcatcgtga cataataaac
    17221 aacgggaagc ctcttttatt gccagtaatg gcgtaaaacc aggcgtgagt tcatccagat
    17281 aattttgttg cggcatataa tcttccttaa tgcttgaata aattaaggcg aaacgcaaat
    17341 aacgcgtttt aatgatctaa aatctaccgc cagcctaagc attgaaagaa gggcattctg
    17401 tgaaagaatt cacaaaaaaa tgaaacc
//
LOCUS       DAJVBX010000089        17403 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.089, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000089 DAJVBX010000000
VERSION     DAJVBX010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 17403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17403
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.089"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(104..205)
                     /locus_tag="OPV72_002505"
                     /pseudo
     CDS             complement(104..205)
                     /locus_tag="OPV72_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477181.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
     gene            complement(206..7473)
                     /locus_tag="OPV72_002506"
                     /pseudo
     CDS             complement(206..7473)
                     /locus_tag="OPV72_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001528616.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7585..13977)
                     /locus_tag="OPV72_002507"
     CDS             complement(7585..13977)
                     /locus_tag="OPV72_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016505166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914772.1"
                     /translation="MDRNRQVNKVVHFLLTLLIMFVASIAPAQALLKGGTWQELNSAT
                     AAVNGTVPRADGAIIPVYQGSMLLDPTKTYDVAFTAMPRDFSADATSTSMRAVNSTDT
                     EGDLFSDPPTIAWENQQPPSVGLLWADAATPDTPLSPQPTPNQTFCAQNLAGRKLVVW
                     PQPDDETTVPALWLYTHTGVPNNAAIPLLSPKVTVNIAQAVGNPVSVSGDHVDASFKA
                     SKVKVGESITLTVTTRGCDGKLVKNAPFVIRREDAKNRQGVVNNTNPVHVGDAELTTV
                     QTEYRGVTDAEGKATVVVTQDEGPGVKTHLIVASQSYPTLTDGVDVIFTTITSPDTAQ
                     ANMYGHMLESASATLNGATYTFTRPKLAVEAGNADESVNDTNETWAQFTWSGADNHCD
                     VLPDAEQLVALRHAHSTLATYTGWPASGDAEYWSSTKDQMNNYHAAVHMNSASVVRAP
                     NSDTLLVSCVDKAQPAAHPQITLSPEGPYKAQVGESIDLVMTVVDKDTQKPLPYRYME
                     LFIDPAKNRKGEHQDAWDNQRVTVSSEDMRASSPEHYTGVTDVNGQAHLTLQHDSGMG
                     GETPIRIVMPDDEGGNVELPFSVIFTVITSPDVDGANMWGHMRGVVDAGNLYKRPLLA
                     VEASHKDGQFSENNEEWATFNSVASATAQCGVGQVPDQSSLAHLYSEHPSGKMEIEHG
                     WPTEDYFIAADSDASGTVHVNLANGDSNKFTNQPNYLTCSANEMVAVLDVYFNDDPTT
                     KNADMTAKVGEQIKLNIHSRNALNDMAIAYTDFTITMANGKRRDGLTTGFTDPSNGEM
                     QFDGVGYLAGQVYHGITDANGDATIILTQNKGVGLLTPLSIAPVDSLIKTPISRSVKF
                     TVATSPDTVKAKMWGHMADTLTVGDWTFERPKLASEVNSPLRTQEESNETWTRVAHID
                     AAGNPDAGGCAANRLPRIDQLEALYSANSGGAMKKTQGWPTLINYWSSTYQSATTWKL
                     IALASGSEFPGSNTSVYTSCLASDNPVPAAITIEPVDPSQWYDGSGVHALKVKKGDTL
                     QLKVTVKDASGKPVPEAPFVLTRGDGYDRKGEKYTAQDGSDLQNIVTPVVIDGESLAW
                     TTTKMGSQTGPDGTRIISVTRPDTHGTRTAITATLYENVAVSASIDTIFTVVTSPDVS
                     VARMWGHMTPSLTAADSAVYKRPLLYDELASKTGAAEYPEDNERWVVFYGPNTTKTVS
                     PEACSKGYFPSVEQLDSLYSKYPNGAIKTAQGWPIIRSYWSGTNAGTITPGAPPYDYY
                     TVDLNDDAHRKVPNISDSDRQYQICAATPQPLAGRITLTSTLATDSDIQAVKAKNSDS
                     IPLVITTTDAAGNPVPYTPFSLIRDAGTARNTSYTFTGSTNMMLAPPTGSAQQFYYNG
                     YTIYGATGADGTAVLTLTQAAGPGVKNVITAALTDTPTVTSTLPVVFTTVTSPDSPQA
                     NMYGHMPETFTASNGAEFKRPLLYSELASTLGVKSYADTNENWPIVNNFDTSNYGACS
                     INQMATLDDLKALYGDHPSGKVTTDIGLPVRKKWWAGDSLLQGQVIYWRYIDLSTGID
                     YSMSGTPGNYYYQLCLTKPRQMNIALSTDAWNADKSAAVAKKGETIPMTVKVTNAAGQ
                     PVSNATVKITRGDALTRAGSVYTTNNADDITLSNIQPSGTATYLLGSVDKYMYAQTDA
                     QGQITFSVSQNNTMGLKTPIRVTVANDITATSSKDVIFTVLTSPDVASANYWGHMPET
                     VEGPDGLRYQRPHLQAEAPSGVNYITVNGEKWAAPTGVQTYTAGQSACDVEYMPLMND
                     LKALQQLYPDGALEDQFGWPVKTGKLWWSADLNSSKAHQAINLKTGQISAPTSTSLQA
                     CLVNARNVPASITLTSTAMDAEKGAAVAKKGEAIPLTVTVKNRAGVPIANEPFTLKRG
                     DANDRLDIKYTWNTTADDLTLQELTPSPTTKSMTASGNVFSGVTGADGTATFTVNQDG
                     SVGLKTELTASATGDVTQSTNTALGVIFNVITSPDTDKAQYWGHMPDTLTVGGVTLHR
                     PLLMKEAPAGATDSRKENNETWVSVYTKADGLTYDMSKNCGGVAGFPAKGVLEKIRDE
                     QMAVANGWPTVSLPYASSTPGTYNYCWVSLAKGGTTHCPTTSSDYSIGYAACLVQP"
     gene            complement(14097..15062)
                     /locus_tag="OPV72_002508"
     CDS             complement(14097..15062)
                     /locus_tag="OPV72_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914773.1"
                     /translation="MQATVKRRLTKVALALVVAGYCAAPAVAANGNLKSGQWQIVSEQ
                     TGTIQGTVPWITRAADKTADTDKDHVTVTIDRGDRKIVTEGDKQFHVGDKVTVNWAIG
                     DTEGDLDVDNAATKLTVQWMRYSDQNGSNPEEIGAKGSDTYEIQAGDADHYIGIKITP
                     TTTTGDPAVATELLLKDLSTDAGGGADGDDIPEGPVVDENVHVVIHEKDSNTNLLKNS
                     GTTLKTNTTYQVLLWSDKNGNGTYDAGENVTDQYDYRWKFVGTSKIAGTGTGGIVNEN
                     WNDKDLVIPLTNAEAKEAFEGAEGGVTVGSDGVQGFGLSIDYKRK"
     gene            complement(15120..17312)
                     /gene="sinH"
                     /locus_tag="OPV72_002509"
                     /pseudo
     CDS             complement(15120..17312)
                     /gene="sinH"
                     /locus_tag="OPV72_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461452.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="intimin-like inverse autotransporter SinH"
BASE COUNT         3253 a         5012 c         4879 g         4259 t
ORIGIN      
        1 atgcgacacc tggtgttatt ttgtatatag gtagcgccag ataccgggtt acagaaggga
       61 aacggcgcat ctacacacca gcggcaaacg gtgatgactc caattagcag aacatatact
      121 tttcaatgaa tgctccgatc actttttcat gaagctcaat tgaacgtgaa aaacaaatta
      181 tttttcgtgc cagacgctta atacgttact ccacgcacgt cgcataacct gctgtacttg
      241 ccggctgaat ggcgcagttt tgctgcttag tattctcatc cacgccgcaa tacatgccgc
      301 cgcccgaggt tgatttagat aaatagggat agcccagcgt cggccagcct aacgagctaa
      361 ttgaatgata cagcgtcaac aggtcgttat tatccggtgc tttgctcagg ctaccgcact
      421 gtttagcaat atcccattta gtgttgtcca ccgtatgcgt catcgcccag tactcgttat
      481 ttgcatgaac tccgttggta aatactggcg tcacgcctga cggtagctca gcctgcagcc
      541 acggacgatg cagcgttttt ccgttgacgg atgtcgtatc cgacatattt ccccagaaca
      601 acgctttatc cgtatccggg ctggtaagta ccataaaaat cacatccagt gaggcgtgaa
      661 gagccgtatt gtccgtcagt ttcaccgtga gtggcgtttt taaccccaga cttttatcct
      721 gattaagcgt aaacgttgcc gtaccgtcgc tgccggtagt gccggtaaag acaatcccgg
      781 tggtggtcat acttcggctg gcgcttgcgg gagtcagctc tttaagcatg agatcatctg
      841 ctccggcatc cgctgccacg tcgccatccg ttaccaccgt acctgcccga tttttcgaat
      901 cgccacgtga caacgtaaaa ccgacgttgg cgaccgggtt accgctgcta tcttttaccg
      961 tcaccgttaa cggcatcgcg cttcccttct ccactaccgc cgcgtttttc gcgctgtcca
     1021 tcgccgtcga ggtcagcgta atattggcag gagtagacgt atgcggctcg accagacaca
     1081 cctgcgcgcc agacacgctc gtggaactgg tgtggccttt ggcgccggta tccagccgca
     1141 gatactggta atacccggtt ccaggctcct ggtccaccgc cagccagctt ttacccgccc
     1201 ctaccggcca gccgaatgcc gtattgagag cgctgtctgg atggtcgcta tacagcgttt
     1261 gcaggtcatt aaacaacggc tgatatgcag catcacaggt ggtcgcgccc gctttctggg
     1321 tgttcgcgat agtcaccaga ggccatgttt cgttattgta atagtaggtg ccgctattcg
     1381 acgtcatctc cgcagccagc agcgggcggt ggaatttcac ccccgcgctg ttggccgccg
     1441 tttccggcat atggccccac attttggctt tatcgctgtc cgggctggta atgacggtaa
     1501 aaatgacatc catattgctg acggtcggcg gattgtcgga cagcatcgcc tgcagcgctg
     1561 ttttcaggcc gggggtatta tcctgcgtca gctcaaactg caccctgccg ctctcatccg
     1621 tagtgccgta ccagtaccag agctgctccc cggaataatg gtaggcaaat actttagcat
     1681 ccgctggcgg cgcaatcggc gttaacagca tgtcgctgtt gttggtgctg tcactaccgc
     1741 cagcccggtt ttgcgaatag tttcctcgcc ccagccgaat gggcacattg ggctacggcg
     1801 tgccggcgcc gtccgtgacg gtcaccgtca gcgggatttt atcccctttt ttcgccagcg
     1861 cggcggattt ttcggcattc atggcgctgg aggtcaacgc tatcgccaac accctgcgct
     1921 tcgccagaca gagctgcgcc gttgaggtat tcgtatttgt gacctgcgta acgccgttat
     1981 ttagcctgat atactggaaa ttattcgtcg agtgcgtatc gttgactttc gaatcccctg
     2041 ctccccagta tttccccgcg tctacaggca acccaaaggc ggccgttagt ccaccattcg
     2101 gatagtcgtt atacaacgtt tttaaatcat ccagcgtcgg caatcccagc cgatcgcacg
     2161 ggctggcgga gtcctgatac aggtttggat agcggttcca ggtgtaccag tgctcattat
     2221 ttgacaggaa ggacgtggta tccgtcgttg aagaaagctc ggcgcgcagc agcggccgcg
     2281 caaactcaac gcccttactg ttggtaaagg tttccggcat atggccccag tatgaggcct
     2341 tgtcgctatc cgggctggtg ataacggtaa agatagcgtc tttgctgtct gtcaggttgc
     2401 tgccgtccat cgtggcggcg ctgatggtgg tctttaaacc tgcggtactg tcctgcgcaa
     2461 gggtaaatgt cacctgtccc tgggcatcgg tttgcgcata cagatatttc gcggaggtat
     2521 ccagcaggta tgtcgccggg ccggacggca tcacattacg cagcgtaata tcgtctgcag
     2581 cgcttgagga cgatgtggcg ctgttgacgc ggttgtacga agatccccgg ctgattttca
     2641 ccatcacgtt tttcatcggc tgacctgcgg cgtctttcac cgtgacggtg gcggccatct
     2701 gctcgccctt tttcgctttt gcgatcccgg tggctgcatc ctggcctgcc agcgtcagcg
     2761 tcaggctggc ggcggcgctg cgtggcgagg taaggcaggt ctgcatatag tacgtcgtgg
     2821 tgctggtcgt cgttttgaca tcattgccgt cgttaaacag gttgaccgcc gcgtagagcg
     2881 actgcgcgcc gtctgacgac atcacgtaat cccccgccca ccagtagcgg ctgacgttat
     2941 tgttgccaga actggtcatc ggccagccgt tacaactgcg catggcgtta tcaggccagg
     3001 tactgtacag cgtctggagg ttgctgacgg tgggcagata attgcgcccg cagccgccgc
     3061 cggcgccgtt ctaggcttta tcgacggtta tcatgcccca ggtttcgcct ttgtcgtagt
     3121 aaccgttggc gatggtcagc gatttgccgg gcgtgacgct gaactcgctg gccagcaacg
     3181 ggcgcttgta caccacgccg ctgctgtcgg tcagcgtttc cgccatatgg ccccagtagt
     3241 tggctttcgg cgtgtccggg ctggtgacga cggtaaaaat gaccggtagc agcgcgctcg
     3301 ttacgccgtt gtgctctatc accgccgtca gcggcgtttt aaagcccgcg ccgctgtcct
     3361 ggctgatatt cagcgtcagc gtgccgtcag cgccggtggc ggtgtaatat ttaacgccgc
     3421 tgctacgccc gtcgctgtgg tttatctgta tctccgccgc cgacgcgcta ttcacttcct
     3481 gattcgcgcg cccgacgctg tcgccgcgcg taaagataac cggcgtgtcg gcggccaggt
     3541 tgccctgggc gtcccgcgtg gtgatgatga ccgggatggt ctcgccgact ttcgctttgg
     3601 caaatccgtc gctgtcgtta tacaaaggcg aagtgagcgt tatctgcgtc gccgccggat
     3661 gggcgttttg caagcagacg aaatagagtt gttcactcca cgccagcgag ctaataccgc
     3721 catcgcgcag atcaatcgac ttaacgtagc ggttttccgt actcctgctc aaatcagcgg
     3781 tgctgttctg gtagttttta ccatccagcg gccagccctg ctgcgtattc atggtgccgc
     3841 cgggcctggc gtcgtacagc gattgcagat cggcaagtgt cggtacgtat cccgcgccac
     3901 aggcgtcgtt cgccacttca aaatcgacga ttccccaggc ttcgttgttt tccgtattgt
     3961 cgccgtgggt aaagccgctg gcgatttcag ccgataacag cgggcgctta aacaccacgc
     4021 cgttggccgc cgtggtcgtt tccggcatat ggccccacat tttggctttg tcgctattag
     4081 ggctggtgac cacagtaaaa atagtgtcga tgctggccgt cgcgctggcg ttatcgtaca
     4141 gcgccgccgt aatcgcgact ttcgtcccgt gggcatccgg gcgggtgacg ttgatgattt
     4201 tgctgccgtt ttcaccggtc atgccgccga ttttggtggc ggtgtcgttg agcgaatcgc
     4261 cgtcaatcac taccgccgag acgatgccgt cgccgcggct gagcacgaac ggcgcttgcg
     4321 gcagcggatt gccgctggcg tcttttaccg tcactttaag ctggagcgta tctccctttt
     4381 tcaccttcac cgcgtgttcg ctgttctcgt cataccacaa tgacgtattc accggctcaa
     4441 tggtgatgga ggctgccgtc gggttatcgc tggcaaggca actgacgtaa tcggatgcgc
     4501 cagcgccgcc cggaaattcg ctaccgttag aaagcgctat cagtttccac gttgtggcgc
     4561 tttgccaggt ggaggtccag taattaatca gcaccggcca gccgtgcgtg ctattgatag
     4621 ccccgtcgcg gttagcggcg taaagcgcct ccagttgatc ggcgcgcggc aatcggttag
     4681 cggcgcagcc gcccgccgcc gtattgccta ccgcatcggc atgggtagcg cgcgcccagc
     4741 tctcgttggc ctcggtttgg gtgcgggtcg cggcaacctc cgccgccagt ttcggtcgct
     4801 caaaggtcat atcgcccacc gtgatggcgt cggacatatg gccccacatt tgcgcatccg
     4861 gcgtatcggg gctggtggga acggtaaact tcacgctgcg gttaacgggg gtggtgatca
     4921 gcgagttaac cggcagtacg gtcagcggcg tcagcaagcc gacaccctgc ggttgttcaa
     4981 tgaccagcgt ggcgttgcct gcggcatcgg tcatgccctg gtacgtcatc gacgccaggg
     5041 aagagccgaa agacgttccg cccatcacca gcgttccgtc gctgggatcg gtaaagcccg
     5101 tggtggcgtt ggcgcgattt ttaccgtgcg acatggtgac ggtaaagctg gcgttgggca
     5161 cgcttaaccc gttcagcgcg ttgacggaat ggacgttcat cgtaattttt tcgcccactt
     5221 tggctaccgc attacgtaac gactcgttgc catcaaagta cacgtccagg ctggtcacca
     5281 actcgttacc ggagcaggag agatagttcg gttcagcgcc gctgaacagg ctgtccgcgc
     5341 cggtcgccag gttaacgtgc gcagtggtgg aaccatcggt atccgccgca atatagctat
     5401 gtttctgtgt cggccagccg taagtcgttt ccatcgtatt gccggaatgg gcttcataca
     5461 gcgtatccag cagcagttgt cccggcacct ggcctgcgcc gcactggttt gtcgctgccg
     5521 tcactgagtt aaacgtggcc cagtactcgt tattctcaaa ttcggaaccg gtatcctgcg
     5581 cggcctcttc cgccagcagc ggacgtttgt aaatattgcc cgcttccacc acgccctgca
     5641 tatggcccca catacgggcc tgcgtcacgt ccgggctggt gacgacggta aaaatcacat
     5701 tctgcgtcgc ttccgtgccg tcgaacagca ccacgcgcac cggggttaat acgccagcgc
     5761 ccttgtcctg ggtcagcgcc agcgaaaact ggccgttggc gtcggtgacg ccgtgatagt
     5821 gaccgtcgcc gccgtccaga ttggcgataa ctaccggttc atccgtccac tgatgcgcgg
     5881 catcaagatc ggcgttcttc tgattctggc gattttgctc gtcgcccagg tagacattaa
     5941 agtagcgata aggcagcggt ttattggtgg cgctgtcggt gacggcgatc ttcatgttga
     6001 tctcttcgcc caccttcact ttcgccgcgt tggccgtcga atcaaaatta tcggtgctaa
     6061 tcactaattt cggcgtgacc gcaggcgagg ctttatccac acagctcacc agcgattgcg
     6121 tggcgtccgg catctgcgta agggcgcggc tgcgcatatc aatgctgatg tggtcagttg
     6181 cgctcgcccc ctgtgaggag gaccagtgct cttcgtcacc ggatgtcacc ccaccggcca
     6241 gccgagagtg gtggctaaat cgccgcgctc gatttttaac ccttccagtt ggcgcgcatc
     6301 cggcagaata tcgcagtgtt tatccgcatg gccccaggtg aactgcgccc agttttcatt
     6361 attgatactg gcgacgcggt cttcgccctc ggtttccgcc gccagtttgg ggcggtcaaa
     6421 agtgtagctt gcgccgtcca ccgtggcggt ggaactgtcc gccatatggc cgtacatgtt
     6481 ggcgctgctg ctgtccgggc tggtgagggt ggtaaaaatc acatccgcgc tggctttcag
     6541 cgcaggcgcg ttcgacgggt gcgccatcag cggggtttta acgcccggcc cgttagcctg
     6601 ggtgacggtc accgtcgcca ccccttccgc gttggtcgtg ccgtggtatt cggtggcagt
     6661 ggtggtgagt tcggtgttgc cgacgcgtac cggcgcggta ttgttcacca cgccctggcg
     6721 gttttgcgca tcgccgcggg taatcacaaa cgcgatattg cccgctggct caccgttaca
     6781 acctttggta ttcaccgtca gcgtgatgct ttcgcccgct ttcaccttcg cggcgttaag
     6841 cgactcatcc agatgatcgg cggtaagggt taccgggtca cccacggcgg gcgcgatatc
     6901 cacggcaaac ttttgttcaa gcacttcgac cgccgtgtta taaggcacgc cggtgcgggt
     6961 aagcaaccac agcggcggca tagcggttga ggtatccagt tgcgaccaga ctaccagatg
     7021 gcggcctgcc atattttgct cacagaacgt caggtttgcc gacgattgtg gagacagcgg
     7081 cgtctccggc gtggcggcgt cggcccatac cagcgtgacg gagggtatcc gttcactctg
     7141 ccagaccagc ggcggctcgg cgaaaatatc gccttcggca tcgcgcggat tggttaaggt
     7201 cagcgcgctg ccgacatcac tggtgctgaa ctggctgggt ttcgcggaat aatcgacggg
     7261 attcgctgca tcagatcgca actgaacgct gccctgataa accgggatcg tcacgccgtc
     7321 agccagcggc ggcgtgccgt taatggcggc agttgagacg tcaggctcct gccatggggc
     7381 gctgctttgc gccgcctggg caaaaaaagc ggtaacacaa aacagacatg cctgtagccc
     7441 ggataaaaga tgggtattcg ttttcagttt caatgcagca cctggaatac atccctttct
     7501 gactattcat tccatcggcg gtaaaaatgc gaaacgtttc actaccggta ccaacgacaa
     7561 tttaccgaaa cccaaccatc ccgatcacgg ctgtacaaga caggcggcat agcctatcga
     7621 gtaatcgctg ctggtggtcg ggcaatgtgt tgtgccccct ttcgctaacg aaacccagca
     7681 ataattatac gtcccaggcg tactgctagc gtaaggcaac gaaactgtcg gccatccgtt
     7741 agcgaccgcc atctgctcat cgcgtatttt ttccagcacg ccttttgccg ggaacccggc
     7801 caccccgcca cagttcttgc tcatatcata ggtaagacca tcggctttcg tataaaccga
     7861 aacccaggtt tcgttatttt ctttccggct atccgtcgcg ccagcaggcg cttctttcat
     7921 caacaagggg cgatgcagcg tcacgccacc aaccgtcagc gtatccggca tatgccccca
     7981 gtactgcgct ttatcggtat ccgggctggt aatcacgtta aagatcacgc ccagcgctgt
     8041 gttggttgat tgcgtgacat cccccgtcgc gctggccgtc agctcggttt ttagccccac
     8101 actgccgtcc tggttcaccg taaacgttgc cgtcccgtca gcccccgtga cgccgctaaa
     8161 cacattgccg gaagccgtca ttgatttcgt tgtcggcgac ggcgtcagtt cctgcaacgt
     8221 caaatcgtct gctgtagtat tccacgtata tttaatgtcg aggcgatcat tcgcatcgcc
     8281 ccgtttcagg gtaaacggtt cattcgctat gggaacgccc gcgcggtttt tcaccgtcac
     8341 cgtcaaggga atagcctcgc cttttttcgc caccgccgcg cctttctccg catccatcgc
     8401 cgtcgaggtt agcgtaatgg aggcagggac attacgcgca ttgaccaaac aggcctgcaa
     8461 gctggtggag gttggcgccg atatctgacc ggttttcagg tttatcgcct ggtgtgcttt
     8521 cgagctattc agatcggcag accaccagag tttaccggtt ttcaccggcc agccgaattg
     8581 atcctccagc gcgccgtcag gatacagttg ctgtagcgcc tttaagtcat tcatcagcgg
     8641 catatactca acgtcgcacg cagactggcc tgccgtatac gtctgtacgc cggtcggcgc
     8701 cgcccatttt tcaccgttca cggtgatgta gttgacgccc gacggcgctt ccgcctgcaa
     8761 atgcgggcgc tggtagcgga ggccgtccgg cccttccacg gtttccggca tatgccccca
     8821 gtagttggcg ctggcgacgt ccgggctggt aaggacggta aatatcacgt ccttactgct
     8881 cgttgcggta atgtcattcg caacggtgac gcggatgggc gttttaagac ccatagtatt
     8941 attttgcgac acgctaaacg ttatttgccc ctgggcgtcc gtttgcgcat acatatattt
     9001 atccaccgac cccagcaagt acgtcgccgt accggaaggc tggatattac ttaaggtaat
     9061 atcgtccgcg ttgttggtgg tatacacgct ccccgcacgc gtcagcgcat cgccgcgcgt
     9121 gattttcacc gtcgcgttgc taacaggctg cccggcagcg ttcgtcacct tcaccgtcat
     9181 ggggatcgtt tcgccttttt tcgccacggc cgccgatttg tccgcgttcc aggcgtccgt
     9241 agagagcgcg atattcatct ggcgcggttt ggtcaggcag agctggtaat agtaattacc
     9301 cggcgttccc gacatggagt aatctatgcc cgtactgaga tcgatatatc gccagtatat
     9361 gacttgacct tgcagcaggc tgtcgcccgc ccaccatttc ttcctgacgg gtaagcctat
     9421 gtcggtcgtg accttgccgc tggggtgatc gccgtacagc gccttgagat catccagcgt
     9481 ggccatctga tttatcgaac aggcgccata attactggta tcaaaattat tcactatagg
     9541 ccagttttca tttgtgtcgg catagctctt cacacctaac gtcgacgcca gctcgctata
     9601 cagcagcggg cgcttaaact ccgcgccgtt gctggcggtg aaggtttccg gcatatggcc
     9661 atacatattg gcctgcgggc tgtccgggct ggtcacggtg gtgaacacca ccggcagcgt
     9721 cgaggttacc gtcggcgtgt cggtcagggc tgcggttatc acgtttttca cccccggccc
     9781 tgcggcctgc gtcagcgtga ggaccgccgt gccgtccgcg ccggtggcac cgtaaatagt
     9841 gtagccatta tagtagaact gttgcgccga accggtgggc ggcgccagca tcatgttagt
     9901 gctgccggta aaggtatagc tggtgttgcg cgccgtcccg gcgtcgcgta tgagggaaaa
     9961 tggcgtataa ggcaccgggt tgcccgccgc atcggtggtg gtgatcacca gcggaatcga
    10021 gtcgctgttt tttgccttca ccgcctggat atcgctatcc gtcgccagcg tagaagtgag
    10081 ggtaatccgc ccggccagag gctgcggcgt cgcggcgcaa atctggtatt gcctgtcgct
    10141 atcactaata ttgggaacct tccggtgcgc atcatcattc agatcgaccg tgtaatagtc
    10201 atagggtggc gcgccggggg tgattgtccc ggcgtttgtg ccgctccagt aagaacggat
    10261 gatcggccag ccctgggcgg tttttatcgc tccgttcggg tatttgctgt acagagaatc
    10321 cagttgctca acggacggga aatacccctt ggagcaagct tccggactaa cggttttggt
    10381 cgtattcggc ccatagaaca ccacccagcg ttcgttgtct tccgggtact ccgcagcacc
    10441 ggtcttgctg gccagttcat cgtagagcag cgggcgcttg tacaccgcgc tatccgcagc
    10501 cgtcagcgac ggcgtcatat gcccccacat gcgggcgacg ctgacatccg ggctggtgac
    10561 gacggtaaag atggtgtcga tgctggcgct cacggcgaca ttttcataca gcgtggcggt
    10621 aatggccgtg cgggtgccgt gggtgtccgg gcgggtgacg ctgatgatgc gggtgccatc
    10681 agggccggtc tgcgacccca ttttggtggt agtccaggcc agcgattcgc cgtcgatcac
    10741 cacgggcgtc acgatatttt gcaaatcgga gccgtcctgg gcggtgtact tttccccttt
    10801 gcgatcgtag ccgtcgccgc gggtgagcac aaacggcgct tccggcaccg gtttgccgct
    10861 ggcgtccttc accgtcacct tcaactgtag ggtatcgccc tttttcactt tcagcgcatg
    10921 gacgccactg ccgtcgtacc actgcgacgg atcgaccggt tcaatggtga tggcggctgg
    10981 caccgggtta tcgctggcca gacaactggt gtaaaccgag gtgttgctgc ccggaaattc
    11041 actgccgctc gccagcgcga tcagtttcca ggtggtggcg ctctggtagg tggacgacca
    11101 gtagttaatt aaggttggcc agccctgagt ctttttcatc gcgccgccgc tgttggcgct
    11161 gtataacgcc tcaagctggt cgatacgcgg caggcggttc gccgcgcagc cgcccgcatc
    11221 cgggttgccc gccgcgtcga tatgggccac gcgcgtccag gtttcattgc tctcttcctg
    11281 agtacgcagc gggctattta cttcactcgc aagcttaggc cgctcaaaag tccagtcgcc
    11341 gacggtaaga gtgtcggcca tgtggcccca cattttggct tttaccgtgt ccgggctggt
    11401 ggcgacggta aacttgacgc tgcgggaaat cggcgtcttg attaatgaat cgacgggcgc
    11461 gatgcttaac ggcgtcagta gccccacgcc cttattctgg gtgaggataa tggtcgcatc
    11521 gccgttggcg tcggtgatcc cgtgataaac ctgcccggca aggtagccca cgccgtcaaa
    11581 ctgcatctcg ccgttgctgg gatcggtaaa gccggtcgtc aatccgtcgc gccgcttgcc
    11641 gttcgccatg gtgatggtga agtcggtata ggcaatcgcc atgtcgttaa gggcgttgcg
    11701 cgaatgaata ttcagcttaa tctgttcgcc gactttggcg gtcatatcag catttttagt
    11761 cgttgggtcg tcgttgaagt agacgtccag caccgccacc atttcattgg ccgagcaggt
    11821 caggtagttc ggctgattgg taaatttgtt gctgtcgccg tttgccaggt tgacgtgtac
    11881 cgttcccgag gcgtcgctat ccgcggcgat gaagtagtct tcggtcggcc agccgtgttc
    11941 gatttccatc ttgccgctgg ggtgctcgct gtataaatgc gccagcgatg actgatccgg
    12001 cacctggccg acgccgcact gcgcggtggc cgacgccacg gagttaaacg tcgcccactc
    12061 ttcgttgttt tcgctgaact gaccgtcttt atggctggct tccaccgcca gcagcgggcg
    12121 tttatacagg ttgccggcat ccaccacgcc gcgcatatgg ccccacatgt tggcgccgtc
    12181 cacatccggg ctggttatta cggtgaaaat gacgctaaag ggcagctcga cgttgccgcc
    12241 ttcatcgtcc ggcatcacga tgcggatggg cgtctcgccc cccatgccgc tgtcgtgctg
    12301 tagcgtcagg tgcgcctgac cgttgacgtc ggtcacgccg gtatagtgtt ccggcgaaga
    12361 ggcgcgcata tcttcggagc tgacggtaac ccgctggtta tcccacgcgt cctgatgctc
    12421 ccctttgcgg tttttcgccg ggtcgataaa cagctccatg taacggtaag gcagcggttt
    12481 ttgcgtgtct ttatcgacta ccgtcatgac cagatcaatc gattccccca cctgcgcctt
    12541 ataaggcccc tccggagaga gggtaatctg cgggtgcgcc gcaggctggg ctttatccac
    12601 acagctaacc agcagcgtat cgctgttggg cgctctgacg accgacgcgc tgttcatatg
    12661 cacggcagcg tggtagttgt tcatctgatc tttggttgac gaccagtatt ccgcatcgcc
    12721 cgacgccggc cagccggtgt acgttgccag cgtactatgc gcatgtctta gcgccaccag
    12781 ttgttcggcg tccggcagaa cgtcgcaatg gttatccgcg ccgctccagg taaactgcgc
    12841 ccaggtttcg ttagtatcgt tgacgctttc gtcagcgtta cccgcctcca ccgccagctt
    12901 cggtcgagtg aaagtgtagg tcgcgccgtt cagcgtggcg ctggcgctct ccagcatgtg
    12961 gccgtacatg ttggcctggg cggtgtcggg gctggtgatg gtggtgaaaa taacgtccac
    13021 gccgtccgtc agcgtaggat aactttgcga agcgacgata agatgcgttt ttacgccggg
    13081 gccttcatcc tgcgtcacca ccacagtggc tttaccctcg gcatcggtga cgccgcgata
    13141 ctccgtttgc acggtcgtta gctcggcatc gccaacgtgc accgggttag tgttattgac
    13201 cacaccctga cggtttttgg catcctcacg gcggatgaca aacggcgcat ttttcaccag
    13261 tttgccatca caccctctgg tcgtgacggt gagggtgatg ctctctccta ctttcacttt
    13321 tgaggcttta aagctggcat caacatgatc gccgctgacc gacacgggat tgcctactgc
    13381 ctgggcaata ttgacagtca ctttcgggct gagcagcggg atggccgcat tattcggcac
    13441 gccggtgtga gtatagagcc acagcgcggg gacggtcgtt tcatcgtctg gctgcggcca
    13501 gacaaccagt ttccgtccgg ccaggttctg ggcgcaaaag gtctggttag gcgtcggctg
    13561 cggcgaaagc ggcgtgtcgg gcgtggcggc atcggcccat aacaggccca cgctcggcgg
    13621 ctgttgattt tcccaggcaa tggtcggcgg atcgctaaag agatcgcctt cggtatcggt
    13681 ggaattgacc gcacgcatcg aggttgaggt ggcatccgcg ctaaaatcgc gcggcatggc
    13741 ggtaaacgca acatcgtagg ttttggtcgg gtcaagcagc atacttccct gatacacggg
    13801 aataatcgcg ccgtcggcgc ggggcacggt gccgttaact gcggcagtgg ctgagttcaa
    13861 ttcttgccag gtcccgcctt tcagtaaggc ctgcgcaggc gcgatcgacg ctacaaacat
    13921 gatcagtaat gtcagtaaga aatgtacaac tttattcact tgccgattcc tgtccatgag
    13981 cgatagccac ccgttttcat tctctgtcgt aattcaaccc actttgctta gcgcgcggct
    14041 aagcaaagtg cgcggaaaat accactcccc gcggggagtg gtatgttgag gacaacttat
    14101 ttgcgtttgt agtcgatgga cagaccaaag ccctggacac cgtcgctacc cacggtaacg
    14161 ccgccttccg caccctcgaa cgcctctttc gcttcggcgt tggtaagcgg gatgacaagg
    14221 tctttatcgt tccagttttc gttgacgata ccaccagtac cggtacctgc aattttactg
    14281 gtgccgacga atttccagcg gtagtcatac tggtcggtaa cgttttcacc ggcatcatag
    14341 gtgccgttgc cgttcttatc gctccacagc aatacctgat aggtagtatt cgttttgagt
    14401 gtcgtccctg aattcttcaa caggttggta ttcgaatctt tctcatgaat aaccacatgg
    14461 acgttttcat ccaccaccgg accttccgga atgtcgtcgc catccgcacc accgcccgca
    14521 tcggtcgaca ggtctttcaa cagcagttcg gttgccacgg cagggtcacc ggtggtggtg
    14581 gttggcgtga ttttgatacc gatataatgg tctgcgtcac ccgcctgaat ttcataggta
    14641 tcgctgcctt tggcgccaat ctcttcggga ttgctaccat tctggtcgct gtatctcatc
    14701 cactgcaccg tcagtttcgt ggcggcgttg tcgacatcca ggtcgccttc cgtatcgcca
    14761 atcgcccagt tgaccgtgac cttatcgcca acgtggaact gcttatcgcc ttcggtcaca
    14821 attttacgat cgccgcgatc gatagttacc gttacgtgat ctttgtcggt atccgcggtc
    14881 ttatccgccg cacgggtaat ccacggcacc gtaccctgaa tggtgcccgt ctgttcagag
    14941 acaatctgcc actgccccga tttcagatta ccgtttgccg ccaccgctgg cgcggcgcaa
    15001 tacccggcaa ctactaatgc taaagcgacc ttcgtcagcc gccgttttac tgttgcttgc
    15061 attcagactc tcttttttct caaaattcag cggctggctg gtcagccata acgctgacgc
    15121 tatttctgac tatacgtaac gcgtataccg taaccctgaa cgccatcttc cacattggcg
    15181 gcaaacttct gcgccgcctc tttattggtt actggcagaa caagatcttc atttatggtg
    15241 ttggccagcg cgccggtatg tccgtttgta ctctgtccgg taaactccca ctggtagtcg
    15301 tacagggcca tctcttcttc cgtgagctgc tcggacatct ggaatacgcc gtctttattc
    15361 ttgtcgcgcc acagcaggaa acggtaggtg ttattaaccg taggatgttt atcttctttg
    15421 ccgatcaggt tgacagggtt ggcggctttg acctgataaa tcaccgcatt cagcgcgctc
    15481 aggttgtcgc cgataaaagt gacatcaacg tagttactgt cgccataggc gtcttctttc
    15541 gccttccagc ggaaagtgcc cggcagggtg ctggaaagcg tcaccgtccc cgcttctttg
    15601 tcacggctgg caataaacac gcagggggtt tccgtggtgc agggcgtctg ggccagcgtg
    15661 acttttttat cattgctgtc gtacaacacg ggcgtcatag catcgtccac cagttcgtta
    15721 ccattgcgat ccgtggagtc gccaaaggag tcggtgatca ggagatccat caccacgccg
    15781 tcttcgccat cggccagcgc gctggcttca tggctgtgat cgctgcgatc gttatcggca
    15841 atgttgtcga cgatcagctc aattttgcga tcctgctgga cggtgatttc caccacgccg
    15901 gagttctgct tattgccctt ttcgtcttcc agcgtcatgc gtactttcca ggtgttcagg
    15961 gcggtgcgct gcgcctcggt atcggcgtta acccaggcag gaagcaccag attccagctg
    16021 ttattgttgc cttcggtcag cgcatccgct tttaccaccg gcatcaccag agtacgggcg
    16081 gcgttgtttt tcgcctgcca ggaagcagaa ataattttgt aatgatggtt aatcagcgcg
    16141 ttgaccgtcc acttacattt ctccagcccc accgcggcct caggcgtatc ttcaatcacg
    16201 cattccgggt gttcgttggt ggcgtcggcc ttcagccaca acgtgacgtc cagcggatct
    16261 ttctcgcggt attcgagaat gatgaaattg ttacgatcga caaaatcggt gcggctgccc
    16321 attaaagagt gctggatttt aacgttttcc ggatcgagtt gcgccgccag cggcgttcct
    16381 atctggtagt tcacagtcgc tttaacgcta aaatcgttat tatcgccagt accggctttg
    16441 taatccgaac caaccgtaac cagcggtacc ggcgtatatt ccagccccaa ggtaacggca
    16501 tgaggatctt tttgcagatt atcggtgcca aacagcgcca cttcatcgcc gtagtactgt
    16561 tcgtaaacta atttagcgcc aagctgcgga taaaagggca gccagctttc catgcggata
    16621 tcccaaccgc gcgcgggtcg ttcttcataa aagtcgaaat cttcggaatc cttccagtca
    16681 gaaagaggat ggtaatagtt gccggagaat ttcaggtaat ccgtccaggc ttcggttccc
    16741 agacctagtc gacggtgacc gcgcgtaaaa tcgtagtcat agaatgcgtt gccgccaagc
    16801 agccagttgc cgacgttctg gcgcacgcca agcccaaagt taccaatagt gcggtcttct
    16861 ttacgttggg ctgagagttg gctaaaaagt aaggtttttt cgttatcata ccagggaacg
    16921 aaataatcca gcgaactgcc gtccagatcg ccgccttcgc ctacggagag gctggtacgg
    16981 atcttgccat aaggtgacat tacgccttca agatatgact gtgctgatga agtgatttgg
    17041 ttttgcaaat agctacgcgc ctaggattcc agcgcttccg gggtgagatt atcaaagccc
    17101 tgggtggcgg aattaataaa gtagtcagcg ccctgttctt taaaggactt tcctttattt
    17161 tcctgttctt cttttttcgc ggattcgctg gctaaatcag gcagggagga gtggctttca
    17221 tcgtttgcag gtacagagtt acctgcgccg gaagccgcaa ctgatactcc agacactaat
    17281 agcaaaacca gaatgcgaat ccttcgcacc atatgatatc cctgttgtta aataaacacg
    17341 ctgctatgag acgatattat atggatgatt catagggaat cataactaac aggcctaaat
    17401 ata
//
LOCUS       DAJVBX010000090        17295 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.090, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000090 DAJVBX010000000
VERSION     DAJVBX010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 17295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17295
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.090"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            12..407
                     /locus_tag="OPV72_002510"
     CDS             12..407
                     /locus_tag="OPV72_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001529886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4751 family protein"
                     /protein_id="HCR9914774.1"
                     /translation="MVGSDRYLFVNTQRANPSIKTVSRFFEYKTWTEQIWRTEIIENG
                     NAFFHWQGHDRKDGHRDTIINYLLNGQRWQSTIEDYIFFHALEGKAWQGHYDNIIEYV
                     SSDHYVYQSAFAEYITDQIHQRAPHGTRF"
     gene            complement(413..1108)
                     /gene="araD"
                     /locus_tag="OPV72_002511"
     CDS             complement(413..1108)
                     /gene="araD"
                     /locus_tag="OPV72_002511"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HCR9914775.1"
                     /translation="MLEDLKHQVLEANLALPKHNLVTLTWGNVSAVDRERGVLVIKPS
                     GVDYSVMTADDMVVVSLETGEVVEGHKKPSSDTPTHRLLYQAFPTIGSIVHTHSRHAT
                     IWAQAGQPIPATGTTHADYFYGTIPCTRKMTEAEINGEYEWETGNVIVEAFEKQGINA
                     AQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEVAYMGIFCRQLAPQLPDMQQSLLDKH
                     YLRKHGAKAYYGQ"
     gene            complement(1249..2751)
                     /gene="araA"
                     /locus_tag="OPV72_002512"
     CDS             complement(1249..2751)
                     /gene="araA"
                     /locus_tag="OPV72_002512"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HCR9914776.1"
                     /translation="MTIFDNYEVWFVIGSQHLYGAETLRQVTQHAEHVVNALNTEAKL
                     PCKLVLKPLGTSPDEITAICRDANYDDRCAGLVVWLHTFSPAKMWINGLSILNKPLLQ
                     FHTQFNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHAVVTGHWQDKEAHTRI
                     GAWMRQAVSKQDTRQLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVV
                     NSIGDGDISALIDEYESSYTLTPATQIHGDKRQNVREAARIELGMKRFLEQGGFHAFT
                     TTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMED
                     YTDHFEKGNDLVLGSHMLEVCPSIAVEEKPILDVQHLGIGGKEDPARLIFNTQTGPAI
                     VASLIDLGDRYRLLVNCIDTVKTPHSLPKLPVANALWKAQPDLPTASEAWILAGGAHH
                     TVFSHALDLNDMRQFAEIHDIEIAVIDNDTRLPAFKDALRWNEVYYGLKR"
     gene            complement(2762..4471)
                     /gene="araB"
                     /locus_tag="OPV72_002513"
     CDS             complement(2762..4471)
                     /gene="araB"
                     /locus_tag="OPV72_002513"
                     /EC_number="2.7.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulokinase"
                     /protein_id="HCR9914777.1"
                     /translation="MAIAIGLDFGSDSVRALAVDCATGDEIATSVEWYLRWQEGRYCD
                     GPNNQFRHHPRDYMESMEAALKAVLAQLSAAQRANVVGIGVDSTGSTPAPIDADGNVL
                     ALRPEFAENPNAMFVLWKDHTAVEEADEITRLCHKPGKVDYSRYIGGIYSSEWFWAKI
                     LHVTRQDSAVAQAAVSWIELCDWVPALLSGTTRPQDIRRGRCSAGHKTLWHESWGGLP
                     PASFFDELDPCINRHLRYPLFSETFTADLPVGTLCAEWAQRLGLPESVVISGGAFDCH
                     MGAVGAGAQPNTLVKVIGTSTCDILIADKQSVGDRAVKGICGQVDGSVVPNFIGLEAG
                     QSAFGDIYAWFSRVLSWPLEQLAAQHPELKTQINASQKQLLPALTDAWAKNPSLDHLP
                     VVLDWFNGRRTPNANQRLKGVITDLNLATDAPALFGGLVASTAFGARAIQECFTEQGI
                     AVNNVMALGGIARKNQVIMQVCCDVLNRPLQIVASDQCCALGAAIFAAVAAKVHADIP
                     AAQQSMASAVERTLRPRPEQAQRFERLYRRYQQWALSAEQHYLPTAAPAPTTPANQAI
                     LTH"
     gene            4812..5657
                     /gene="araC"
                     /locus_tag="OPV72_002514"
     CDS             4812..5657
                     /gene="araC"
                     /locus_tag="OPV72_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose operon transcriptional regulator AraC"
                     /protein_id="HCR9914778.1"
                     /translation="MAETQNDPLLPGYSFNAHLVAGLTPIEANGYLDFFIDRPLGMKG
                     YILNLTIRGEGVINNNGEQFVCRPGDILLFPPGEIHHYGRHPDASGWYHQWVYFRPRA
                     YWQEWLTWPTIFAQTGFFRPDEARQPHFSELFGQIISAGQGEGRYSELLAINLLEQLL
                     LRRMAVINESLHPPMDSRVRDACQYISDHLADSHFDIASVAQHVCLSPSRLSHLFRQQ
                     LGISVLSWREDQRISQAKLLLSTTRMPIATVGRNVGFDDQLYFSRVFKKCTGASPSEF
                     RARCE"
     gene            5776..6543
                     /locus_tag="OPV72_002515"
     CDS             5776..6543
                     /locus_tag="OPV72_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HCR9914779.1"
                     /translation="MQALLEHFITQSTLYSLIAVLLVAFLESLALVGLILPGTVLMAG
                     LGALIGSGELNFWHTWLVGIIGCLMGDWISFWLGWRFKKPLHRWSFMKKNKSLLDKTE
                     HALHQHSMFTILVGRFVGPTRPLVPMVAGMLDLPVAKFIGPNLIGCLLWPPFYFLPGI
                     LAGAAIDIPSDMQSGDFKWLLLATALLLWVGGWLCWRLWRSGKAAVDRLTAYLPRSRL
                     LYLAPLTLGIGVVALVVLVRHPLMPVYIDILRKVVGY"
     gene            complement(6582..7289)
                     /gene="thiQ"
                     /locus_tag="OPV72_002516"
     CDS             complement(6582..7289)
                     /gene="thiQ"
                     /locus_tag="OPV72_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine ABC transporter ATP-binding protein
                     ThiQ"
                     /protein_id="HCR9914780.1"
                     /translation="MLKLIDITWLYHHLPMRFTLAVERGEQVAILGPSGAGKSTLLNL
                     IAGFLAPASGTLLIAGEDHTLTPPSRRPVSMLFQENNLFSHLNVQQNIGLGLNPGLTL
                     NASQREKRDAIARQMGIESLMARLPGELSGGQRQRVALARCLVREQPVLLLDEPFSAL
                     DPALRQEMLTLVSDICRERQLTLLMVSHSVEDAARIAPRSIVVADGRIAWQGKTDELL
                     SGQASASALLGIKSHIL"
     gene            complement(7273..8883)
                     /gene="thiP"
                     /locus_tag="OPV72_002517"
     CDS             complement(7273..8883)
                     /gene="thiP"
                     /locus_tag="OPV72_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine/thiamine pyrophosphate ABC transporter
                     permease ThiP"
                     /protein_id="HCR9914781.1"
                     /translation="MATRRQPLIPGWLIPGLCAAALMITVSLAAFLALWLNAPSGAWS
                     TLWRDSYLWHVVRFSFWQAFLSAVLSVVPAVFLARALYRRRFPGRLALLRLCAMTLIL
                     PVLVAVFGILSVYGRQGWLASLWQMLGLQWTFSPYGLQGILLAHVFFNLPMASRLLLQ
                     SLESIPGEQRQLAAQLGMRGWHFFRFVEWPWLRRQIPPVAALIFMLCFASFATVLSLG
                     GGPQATTIELAIFQALSYDYDPARAAMLALIQMVCCLALVLLSQRLSKAIAPGMTLTQ
                     GWRDPDDRLHSRLTDALLIVLALLLLLPPLVAVVVDGVNRSLPEVLAQPILWQAVWTS
                     LRIALAAGVLCVVLTMMLLWSSRELHQRQQLFAGQTLELSGMLILAMPGIVLATGFFL
                     LLNNSVGLPESADGIVIFTNALMAIPYALKVLENPMRDITARYGMLCQSLGIEGWSRL
                     KVVELRALKRPLAQALAFACVLSIGDFGVVALFGNDNFRTLPFYLYQQIGSYRSQDGA
                     VTALILLLLCFTLFTLIEKLPGRHAKTD"
     gene            complement(8859..9842)
                     /locus_tag="OPV72_002518"
     CDS             complement(8859..9842)
                     /locus_tag="OPV72_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine ABC transporter substrate binding
                     subunit"
                     /protein_id="HCR9914782.1"
                     /translation="MLKKYLPLLLLCAAPAFAKPVLTVYTYDSFAADWGPGPAVKKAF
                     EADCNCELKLVALEDGVSLLNRLRMEGKNSKADVVLGLDNNLLEAATQTKLFAKSGVA
                     NEAVKVPGGWKNDTFVPFDYGYFAFVYDKSKLKNPPKSLKELVESDQKWRVIYQDPRT
                     STPGLGLLLWMRKVYGDNAPQAWQKLAAKTVTVTKGWSEAYGLFLKGESDLVLSYTTS
                     PAYHIIEEKKDNYAAANFSEGHYLQVEVAARTVASKQPELAEKFLKFMVSPAFQNAIP
                     TGNWMYPVADVALPAGFESLAKPATTLEFTPQQVAAQRQAWISEWQRAVSR"
     regulatory      complement(9874..9973)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(10020..11678)
                     /gene="sgrR"
                     /locus_tag="OPV72_002519"
     CDS             complement(10020..11678)
                     /gene="sgrR"
                     /locus_tag="OPV72_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator SgrR"
                     /protein_id="HCR9914783.1"
                     /translation="MPSGRLQQQFIRLWQCCDGKTQDTTLNELADLLNCSRRHMRTLL
                     NTMQARGWLTWEAEVGRGKRSRLTFLYTGLALQQQRAEDLLEQDRIDQLVQLVGDKSA
                     VRQMLISHLGRSFRQGRHILRVLYYRPMHNLLPGTALRRSETHIARQIFSSLTRVNEE
                     NGELEADIAHHWQQISPLLWRFYLRPGIHFHHGRELEMEDVIASLTRINTLPLYSHIT
                     KIDSPTAWTLDIHLSQPDRWLPWLLGQVPAMILPREWETLANFASHPIGTGPYAVRRN
                     TPNQLKILAFDDYFGYRALIDEVNVWVLPDISEEPACGLMLEGPIQGGEKAIESRLEE
                     GCYYLLFDARTPRGAHPQVREWVSHVLSPTNLLYHADEPLQQLWFPAYGLLPRWHHAR
                     PGPGEKPAGLETLTLTFYREHIEHRVIARIMSALLAEHQVHLHIQEIDYDQWHAGEIE
                     SDIWLNSANFTLPLDFSLFAHLCEVPLLQNCIPRDWQDDAAQWRAGEMNLANWCQQLL
                     ANKAIVPLIHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDP"
     gene            11771..11893
                     /gene="sgrT"
                     /locus_tag="OPV72_002520"
     CDS             11771..11893
                     /gene="sgrT"
                     /locus_tag="OPV72_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001248755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake inhibitor SgrT"
                     /protein_id="HCR9914784.1"
                     /translation="MRQFWLRYFAATEKTSWLACLSAPQRLKMLAELMQWEATD"
     gene            complement(12228..12833)
                     /gene="leuD"
                     /locus_tag="OPV72_002521"
     CDS             complement(12228..12833)
                     /gene="leuD"
                     /locus_tag="OPV72_002521"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HCR9914785.1"
                     /translation="MAEKFTQHTGLVVPLDAANVDTDAIIPKQFLQKVTRTGFGAHLF
                     NDWRFLDEKGQQPNPEFVLNFPEYQGASILLARENFGCGSSREHAPWALTDYGFKVVI
                     APSFADIFYGNSFNNQLLPVKLSDEQVDELFTLVKANPGIKFEVDLEAQVVKAGDKTY
                     SFKIDDFRRHCMLNGLDSIGLTLQHEDAIAEYENKQPAFMR"
     gene            complement(12844..14244)
                     /gene="leuC"
                     /locus_tag="OPV72_002522"
     CDS             complement(12844..14244)
                     /gene="leuC"
                     /locus_tag="OPV72_002522"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HCR9914786.1"
                     /translation="MAKTLYEKLFDAHVVFEAPNETPLLYIDRHLVHEVTSPQAFDGL
                     RAHHRPVRQPGKTFATMDHNVSTQTKDINASGEMARIQMQELIKNCNEFGVELYDLNH
                     PYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQ
                     GRAKTMKIEVTGNAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGDAIRALSMEGRMT
                     LCNMAIEMGAKAGLVAPDETTFNYVKGRLHAPKGRDFDEAVEYWKTLKTDDGATFDTV
                     VTLRAEEIAPQVTWGTNPGQVISVTDIIPDPASFSDPVERASAEKALAYMGLQPGVPL
                     TDVAIDKVFIGSCTNSRIEDLRAAAEVAKGRKVAPGVQALVVPGSGPVKAQAEAEGLD
                     KIFIEAGFEWRLPGCSMCLAMNNDRLNPGERCASTSNRNFEGRQGRGGRTHLVSPAMA
                     AAAAVTGHFADIRSIK"
     gene            complement(14247..15338)
                     /gene="leuB"
                     /locus_tag="OPV72_002523"
     CDS             complement(14247..15338)
                     /gene="leuB"
                     /locus_tag="OPV72_002523"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HCR9914787.1"
                     /translation="MSKNYHIAVLPGDGIGPEVMAQALKVMDAVRSRFDMRITTSRYD
                     VGGIAIDNHGHPLPKATVEGCEQADAILFGSVGGPKWENLPPESQPERGALLPLRKHF
                     KLFSNLRPAKLYQGLEAFCPLRADIAANGFDILCVRELTGGIYFGQPKGREGSGQYEK
                     AFDTEVYHRFEIERIARIAFESARKRRRKVTSIDKANVLQSSILWREIVNDVAKAYPD
                     VELAHMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQE
                     FGLYEPAGGSAPDIAGKNIANPIAQILSLALLLRYSLDADEAATAIEQAINRALEEGV
                     RTSDLARGAAAVSTDEMGDIIARYVAEGV"
     gene            complement(15338..16909)
                     /gene="leuA"
                     /locus_tag="OPV72_002524"
     CDS             complement(15338..16909)
                     /gene="leuA"
                     /locus_tag="OPV72_002524"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016831521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HCR9914788.1"
                     /translation="MSQQVIIFDTTLRDGEQALQASLSAKEKLQIALALERMGVDVME
                     VGFPVSSPGDFESVQTIARTIKNSRVCALARCVEKDIDVAAQALKVADAFRIHTFIAT
                     SPMHIATKLRSTLDEVIERAVYMVKRARNYTDDVEFSCEDAGRTPVDDLARVVEAAIN
                     AGARTINIPDTVGYTMPFEFAGIISGLYERVPNIDKAIISVHTHDDLGIAVGNSLAAV
                     HAGARQVEGAMNGIGERAGNCALEEVIMAIKVRKDIINVHTNINHHEIWRTSQTVSQI
                     CNMPIPANKAIVGSGAFAHSSGIHQDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGR
                     AAVKHRMEEMGYKDTDYNMGHLYDAFLKLADKKGQVFDYDLEALAFINKQQEEPEHFR
                     LDYFSVQSGSSDIATASVKLACGEEIKAEAANGNGPVDAIYQAINRITGYDVELVKYD
                     LNAKGQGKDALGQVDIVVNHHGRRFHGVGLATDIVESSAKAMVHVLNNIWRAAEVEKE
                     LQRKAQNKENNKETV"
     gene            complement(16997..17083)
                     /gene="leuL"
                     /locus_tag="OPV72_002525"
     CDS             complement(16997..17083)
                     /gene="leuL"
                     /locus_tag="OPV72_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leu operon leader peptide"
                     /protein_id="HCR9914789.1"
                     /translation="MSYIVRFTGLLLLNAFIVRGRPVGGIQH"
BASE COUNT         3697 a         4783 c         4873 g         3942 t
ORIGIN      
        1 tgcaggcgcg tctggtaggg agcgaccgtt atcttttcgt caatactcaa cgcgctaacc
       61 cttccataaa aaccgtgagt cgattttttg agtataaaac atggacagaa cagatttggc
      121 gtaccgagat tattgaaaac ggcaatgctt tttttcactg gcaaggacac gacagaaaag
      181 acggacatcg ggataccatt attaattatc tgttaaatgg gcaacgctgg cagtcaacaa
      241 tcgaagatta tattttcttc catgcgctgg aaggaaaagc gtggcaggga cattatgata
      301 atattattga atatgtgagt tctgatcatt acgtctatca aagcgcattt gctgaatata
      361 tcaccgacca gattcatcaa cgcgcccccc atgggacgcg tttttagagg cattactgcc
      421 cgtaataggc ttttgcgccg tgtttgcgta aatagtgttt atccagcagg gattgctgca
      481 tgtcgggcaa ctgcggcgca agctggcggc agaagatccc catataggcc acttcttcca
      541 gcacgatggc gttatgcacg gcatcctcgg catttttacc ccaggcaaac gggccgtgcg
      601 aatggacaag cacgccgggc atttgagcgg cgttaatgcc ttgtttttca aaggcttcaa
      661 caatgacatt gcccgtttcc cattcatact cgccattaat ttccgcctcg gtcattttgc
      721 gagtgcaggg aatcgtaccg tagaaatagt cggcgtgggt ggtgcccgtc gccggaatcg
      781 gctgacccgc ctgcgcccag atagtcgcgt ggcgcgaatg ggtgtgtacg atgctgccga
      841 tagtcggaaa tgcctgatat aacagacggt gggttggcgt atcggacgac ggtttcttat
      901 gaccttcaac gacttcaccg gtctccaggc tgaccaccac catatcgtca gcggtcatga
      961 cgctataatc gacgccggac ggcttaatca ccagtacgcc gcgttcgcga tcgacggcgc
     1021 taacgttacc ccaggtgagg gtgaccaggt tgtgttttgg cagcgccaga ttggcttcca
     1081 gtacctggtg tttgagatct tctaacattg ttttctccct gccggatggc gcttcgctta
     1141 tccggcctac gagcgacggt gtgccggatg gcgacataaa tgccttattc ggcctacagg
     1201 accgtaggcc cggtaaacgc agtgccaccg ggcattcaga caccactttt agcgttttaa
     1261 accgtaatac acctcgttcc agcgcagcgc gtccttaaag gctggcagac gggtatcgtt
     1321 atcaatcacc gcgatttcga tatcgtgtat ttctgcgaac tggcgcatat cgttcagatc
     1381 cagcgcgtgg ctgaagacgg tatggtgcgc gccgccagcc agaatccacg cttcggaggc
     1441 ggtcggcaga tccggctgcg ccttccacag cgcgttagcc accggcagtt tcggcaggga
     1501 gtgcggcgtt tttacggtgt caatgcagtt gaccagcagg cggtaacgat cgccgaggtc
     1561 gatcaggctg gcgacgatcg ccgggccggt ttgggtattg aaaatcaaac gcgccggatc
     1621 ttccttgccg ccaatgccga ggtgctggac gtcgaggatc ggtttctctt ccaccgcgat
     1681 ggagggacac acttccagca tgtgcgagcc gagcaccaga tcgttgcctt tctcgaagtg
     1741 gtcagtgtaa tcctccataa atgaggtgcc gccctgcaga ccggttgaca tcactttcat
     1801 aatgcgaagc agagcggcgg ttttccagtc gccttcgccc gcaaagccgt agccctgctg
     1861 catcagacgc tgtacggcca gacccggaag ttgtttcaga ccgtgtaaat cttcaaaagt
     1921 agtagtgaat gcgtggaagc cgccctgttc caggaaacgc ttcatcccca gttcaatgcg
     1981 cgccgcttcc cgcacgttct ggcgtttatc gccgtggatc tgggtggcgg gcgtcagggt
     2041 atagctgctt tcatactcgt caatcagagc gctgatatcg ccgtcgccga tagaattcac
     2101 cacctgcacc agatcgccga ccgcccaggt attgaccgaa aagccaaatt tgatttgcgc
     2161 ggccacttta tcaccgtcag tcactgcgac ttcacgcata ttgtcgccga agcggcagac
     2221 ttttagctgg cgggtatcct gtttagagac cgcctggcgc atccaggcgc cgatacgcgt
     2281 atgggcctct ttatcctgcc agtggccagt gacgaccgcg tgctgctggc gcatccgcgc
     2341 gccgataaaa ccgaactctc ggccgccatg cgcagtctgg ttcaggttca taaagtccat
     2401 atcgatgctg tcccacggca gggcggcgtt aaattgggta tggaattgca gtagtggttt
     2461 gttaaggata ctcagcccgt tgatccacat tttggccggg gagaaggtgt gcagccagac
     2521 caccagcccc gcgcagcgat cgtcataatt ggcgtcacga caaatggcgg taatctcatc
     2581 cggcgaggtg cccagcggtt ttaataccag tttacatggc agtttggctt cggtattcag
     2641 cgcgttgacc acatgctcgg catgttgggt gacctggcgc agggtttctg cgccatacaa
     2701 atgctggctg ccaatcacaa accatacttc ataattatca aaaatcgtca ttgtcgtgtc
     2761 cttaatgagt caggattgcc tgattggccg gggtcgttgg cgccggcgcg gcagtcggaa
     2821 gataatgttg ttctgcgctt agcgcccact gctggtagcg gcggtaaagc cgttcgaagc
     2881 gttgcgcctg ttcagggcgg ggacgcagag tgcgttctac cgcgctcgcc atgctttgct
     2941 gggcggcagg aatatcggca tggactttcg cggcaacggc ggcaaagata gcggcgccta
     3001 atgcgcaaca ttggtcggaa gcgacgatct gcaacggacg attcagtacg tcgcagcaga
     3061 cctgcataat gacctgattt ttacgggcga tgccgccaag cgccatcacg ttattgaccg
     3121 cgataccctg ctcggtaaaa cactcctgaa tggcgcgcgc gccgaaggcg gtcgaggcga
     3181 ccagaccgcc aaacagcgct ggcgcgtcgg tggcgagatt gagatcggta atgacgcctt
     3241 tcagacgctg gttggcattg ggtgtacggc gaccattgaa ccagtcgagc accaccggca
     3301 ggtgatccag ggacggattt ttcgcccagg cgtcggtgag cgctggcaat agctgcttct
     3361 ggctggcgtt aatctgggtt ttcagttccg ggtgctgcgc ggcaagttgt tccagcggcc
     3421 agctcaacac gcggctaaac caggcgtaga tgtcgccgaa agcggactgg cccgcttcca
     3481 gaccgataaa gttcggcacc acgctgccgt caacctgacc gcaaatgcct ttcacggcgc
     3541 gatccccgac gctctgttta tccgcaatca gaatgtcgca ggttgacgtg ccgatgactt
     3601 ttaccagcgt attgggctgt gcgcccgcgc cgaccgcgcc catgtgacag tcgaacgcgc
     3661 cgccggaaat caccacgctt tccggcaagc cgaggcgctg cgcccattcg gcgcacaggg
     3721 tgcccacggg cagatcggcg gtgaaggttt cgctaaataa cgggtagcgc agatgacggt
     3781 taatgcacgg atcgagttca tcaaagaagc tcgcgggcgg cagaccgccc cagctttcat
     3841 gccacagtgt tttgtgccca gcgctgcagc ggccacggcg gatatcctgc gggcgagtgg
     3901 tgccggaaag cagcgccggc acccagtcac acagttcaat ccacgagacg gcggcctgcg
     3961 cgacggcgct atcctggcgg gtgacgtgca gaatcttcgc ccagaaccat tcgctggagt
     4021 aaatgccgcc aatatagcgg gagtagtcga ccttacctgg cttatggcac agacgagtga
     4081 tttcgtcggc ttcttccacg gcggtgtgat ctttccacag cacaaacatc gcattcgggt
     4141 tctcggcgaa ctccggacgc agcgccagga cgttaccgtc ggcgtcaatc ggcgctggcg
     4201 tagaaccggt gctgtcaacg ccaatgccaa cgacatttgc gcgttgcgcg gcgcttaatt
     4261 gtgccagaac ggctttcagc gcggcctcca ttgactccat gtagtcgcgc ggatgatgac
     4321 ggaactggtt gttcgggccg tcgcaataac ggccttcttg ccagcgcaga taccactcta
     4381 cgctggtggc gatctcgtcg ccggtggcgc agtccactgc cagagcgcgc actgaatcac
     4441 tgccaaaatc gaggccaatt gcaattgcca tcgtcttact ccatccagaa aaacaggtat
     4501 ggagaaacag tagagagtcg cggcaaaaac cgtcaggcag gatccgctaa tcttatggac
     4561 aaaaatgcta atgctttgca aagtgtgacg ctgtgcaaat attcaatgtg gacattccag
     4621 ccatagttat agacacttct gttacttaat tttatcgcct gaactgtacg cttttgttac
     4681 aaagcgcttt tcacaagcgg ggttgatacg tgctttcatc aagcgcaagg tcttgcggag
     4741 acggaagctc tgtcgtcctg gtcaatatgg acaatttgtt tcttctctga acatcggggg
     4801 gtagagaaat catggctgaa acgcaaaatg atccgctatt gccgggatat tcatttaatg
     4861 cccatctggt cgccgggctg acgccaattg aagcgaatgg atatctggat ttttttatcg
     4921 atcgtccgtt gggcatgaag ggatatattc ttaacctgac catccgcgga gagggcgtca
     4981 ttaataataa tggcgagcag tttgtctgtc ggcctggcga tatattattg tttccgccgg
     5041 gcgagattca tcactatgga cggcatccgg atgccagcgg gtggtatcac cagtgggttt
     5101 atttccggcc tcgcgcctac tggcaggagt ggctgacctg gccgacaatc tttgctcaga
     5161 caggattttt ccgcccggac gaggcgcgcc agccgcattt cagcgaactg ttcgggcaga
     5221 tcatcagcgc cgggcaaggg gaaggtcgct attctgagct actggcgatc aatctgctgg
     5281 agcagttgtt gctcagacgt atggcggtaa ttaatgagtc gttgcatccg ccgatggata
     5341 gccgtgtgcg cgatgcctgc cagtatatca gcgaccatct ggcagacagt cattttgata
     5401 tcgccagcgt cgcccagcat gtctgcctgt cgccctcccg gttatcgcat ctgttccgcc
     5461 agcagttagg cattagcgta ttgagctggc gcgaagatca gcgtatcagc caggcgaaac
     5521 tcctgcttag caccacgcga atgccgatag cgaccgttgg gcgcaatgtt ggatttgacg
     5581 atcagctcta tttttcgcgg gtatttaaaa aatgcaccgg ggcaagtcct agcgagttca
     5641 gggccagatg tgaataaaaa gtgaatgatg tgtccacaaa gatgtcataa gccgtaacta
     5701 ttcggataat tgacggcttg acgaaggggg acggggtaag cagaatccct gcttcatcac
     5761 gctgacggac acactatgca agcactgctg gaacacttta tcacccaatc cactctgtat
     5821 tcgctcatcg ccgtgttgct ggtcgccttc ctggaatcgc tggcgctggt ggggttgatt
     5881 ttacccggca cggtactgat ggcggggctg ggcgcgctta tcggcagcgg cgagctcaat
     5941 ttttggcata cctggctggt gggtattatc ggctgtctga tgggcgactg gatttcgttc
     6001 tggctggggt ggcgctttaa aaagccgcta caccgctggt cttttatgaa aaagaacaag
     6061 tcgctgctgg ataaaaccga acatgcgctg catcagcaca gtatgttcac gatcctggtc
     6121 ggacgttttg tcggtccgac gaggccgctg gtgccgatgg tggcagggat gctggatctt
     6181 cccgtagcga aatttattgg gccaaacttg attggctgtt tgctgtggcc gccgttttat
     6241 ttcctgccgg gcattctggc gggagcggca atcgatattc cttccgatat gcagagcgga
     6301 gatttcaaat ggctgctgct ggcgacggcg ttgctgctgt gggtcggagg ctggctatgc
     6361 tggcggctgt ggcgcagcgg caaagcggca gtcgatcgtt taaccgcgta tctcccccgc
     6421 agccgtttgc tgtatctggc gccgttgacg ctcgggatcg gcgtggtcgc gctggtggtg
     6481 ctggttcgcc acccgctgat gccggtgtat atcgatattc tgcgcaaagt tgtgggttac
     6541 taacgattcc tttgccggat ggcggcttcg ccttatccgg cctacaaaat atgggatttg
     6601 atgcccaata gcgctgaggc gctggcttga ccgcttagta gctcgtctgt tttgccttgc
     6661 cacgcaatgc gtccgtcggc gacgacgatt gaccggggcg caatccgcgc cgcatcttcc
     6721 acgctgtgcg agaccatcaa cagcgtgagc tgtcgctcgc ggcagatatc gctgaccaac
     6781 gtcagcatct cctggcgcag cgcgggatcg agcgcggaga acggttcatc cagcagcagc
     6841 accggctgtt cacgtaccag gcagcgcgcc agcgctaccc gctgacgctg cccgccggac
     6901 agttcgcccg gtaaacgcgc catcagactc tcaatgccca tctgacgtgc gatagcgtcc
     6961 cgtttttccc gctggctggc gttgagcgtt aacccagggt ttagccccag accgatattt
     7021 tgctgcacat tcaggtggct gaataaatta ttctcctgaa acagcattga gaccggacgg
     7081 cgtgagggcg gcgtaagcgt atggtcttcg ccggcaatca gtagcgtacc gctggcaggc
     7141 gcaagaaaac cggcaattaa attcaacaac gtgcttttcc ccgcgccgct ggggccaaga
     7201 atcgccacct gctcgccgcg ttctaccgcc agcgtaaaac gcatcggcaa atgatggtaa
     7261 agccaggtga tatcaatcag ttttagcatg tcggcccggt agtttctcta tgagggtaaa
     7321 taacgtaaaa cagagcagca acagtatcag cgcggtcacc gcgccgtcct ggctgcggta
     7381 ggagccgatc tgctgataca gataaaacgg cagcgtgcgg aaattgtcat tgccgaaaag
     7441 cgcgacgacg ccaaaatcac cgatagaaag tacgcaggca aacgccagcg cctgcgccag
     7501 cggacgtttc agcgcccgca gttccacgac ctttaaccgc gaccagcctt caattcccaa
     7561 tgactggcac agcattccat aacgggcggt aatatcgcgc attgggtttt ccaggacttt
     7621 tagcgcgtag gggattgcca tcagcgcatt ggtgaaaatc acgatgccgt cggcggattc
     7681 cggtaagcca acgctgttat tgagcagtaa aaagaagcct gtcgccagca cgatccccgg
     7741 catcgcgagg atcaacattc cgctgagttc cagcgtttgt ccggcgaata gttgctggcg
     7801 ttggtgtagc tcgcggctac tccacagcag catcatggtc agcaccacac acagaacgcc
     7861 cgccgccagc gcaatgcgta gcgatgtcca gacagcctgc cacagaatgg gttgcgccag
     7921 cacttccggc aggctgcggt tgacgccatc gaccaccacg gcgaccagcg gcggaagcag
     7981 caatagtagc gccagcacga ttaataaggc gtccgtcaga cggctgtgga gacgatcgtc
     8041 aggatcgcgc cagccctgcg tcagcgtcat ccccggcgca atcgctttgc tcaaccgttg
     8101 acttagcagt accagcgcca ggcagcagac catctggatt aatgccagca tcgccgcgcg
     8161 ggcgggatcg tagtcataac tgagcgcctg aaagatagcc agttcgatag tggtggcctg
     8221 cgggccgccg ccgagcgaca ggaccgttgc gaaactggcg aagcagagca taaaaatcag
     8281 cgccgcgacg ggcggaattt ggcggcgcag ccacggccat tcgacaaaac ggaaaaaatg
     8341 ccagccgcgc ataccgagct gggcggcgag ctggcgctgc tcgccgggaa tgctttccaa
     8401 cgattgcagc aacaaacggc tcgccattgg cagattaaaa aagacgtgcg ccagtaaaat
     8461 gccctgcaag ccgtaggggg agaatgtcca ctgaagcccc agcatctgcc acagcgaggc
     8521 cagccagccc tgacgtccat acacgctaag aatgccgaac acggcaacca gtaccggcag
     8581 aatcagcgtc atggcgcaca gacgcagcag cgccagacgt ccaggaaaac ggcgtcgata
     8641 aagcgcgcgg gcgagaaaaa ccgccgggac cacagacagc actgcggaca gaaacgcctg
     8701 ccagaatgag aagcgcacca catgccacag atagctatcc cgccagagtg tcgaccacgc
     8761 gcccgacggc gcgttcagcc aaagcgccag aaaggccgcc agcgagacgg ttatcatcag
     8821 cgcggcggcg cacagccccg gaatcagcca gccgggaatt aacggctgac ggcgcgttgc
     8881 cattcgctaa tccatgcctg gcgttgtgct gccacttgtt gcggcgtgaa ttccagcgtt
     8941 gtggcgggtt tggccaatga ttcaaaccct gcgggtaagg cgacgtccgc taccgggtac
     9001 atccagttgc cggtgggtat ggcgttctga aacgccggag aaaccataaa tttgaggaat
     9061 ttctccgcca gttccggctg cttactggcg acggtacgcg ccgcgacttc tacctgtaag
     9121 taatggcctt cgctgaagtt cgcggcggcg taattgtcct tcttctcttc aataatgtga
     9181 tacgccggag aggtggtgta actgagcacc aaatcgcttt cacctttcag aaataaaccg
     9241 taggcctcgc tccagccttt cgtcaccgtc accgttttgg ccgccagttt ttgccaggcc
     9301 tgcggcgcgt tatcgccata aactttgcgc atccacagta acagccccag ccctggcgta
     9361 ctggtacgcg gatcctgata aatcacccgc catttttgat cgctctcgac cagttctttc
     9421 aggcttttcg gcggattttt cagcttgctt ttatcgtaga caaaggcgaa atagccgtaa
     9481 tcgaacggca caaatgtgtc gtttttccag ccgccgggca ccttgaccgc ctcattcgcc
     9541 acgccgcttt tggcaaagag tttagtttgc gtggccgcct ccagcagatt attgtccagc
     9601 cccaacacca catcggcttt gctgttcttc ccctccatcc gcaggcggtt gagcagcgaa
     9661 acgccatcct ccagcgccac cagtttcagc tcgcagttgc aatcggcttc aaacgctttt
     9721 ttcaccgccg ggcctggccc ccagtcggcg gcgaacgagt cgtaggtata gacggtgaga
     9781 acgggtttgg cgaaagcagg cgccgcgcac aggagtaaaa gcggaagata tttttttaac
     9841 actttgcacc tcagttaaag agtggcaaag gacttgagag gtagcctcaa atcccttcgc
     9901 cggcattatc cggatcaggt tcgacgggta ttttctcagc gcgcgcatga gcgcggcacc
     9961 ccgttgagtt cggcgttagt gtagtgattt tgttgccggg cagcaatcaa gagctggcgt
    10021 taaggatctg gcggcgcaaa ccacgccgat ttaaaatcaa accagccgag ggtattcatg
    10081 cgcagcccgc gcatactgcg ttgtccctgg ataatcagcc agtggtggat caacggcaca
    10141 atcgctttgt tggccagcag ttgctggcac cagttcgcca ggttcatctc gccagcgcgc
    10201 cactgcgcgg cgtcgtcctg ccagtcgcgc ggaatgcagt tctgcaagag cggtacttcg
    10261 cacaggtgcg cgaacagcga gaaatccagc ggcagcgtaa agttagcgct attgagccag
    10321 atatcgcttt cgatctcgcc ggcgtgccat tgatcgtagt cgatctcctg aatatgcaga
    10381 tgcacctgat gttcagccag aagcgcgctc atgatacggg cgataacccg gtgctcaatg
    10441 tgttcgcgat agaaggtcag cgtgagggtt tccagcccgg cgggtttttc gcccgggcct
    10501 ggacgggcgt ggtgccagcg cggtaaaagc ccataggccg ggaaccagag ctgctgtagc
    10561 ggttcatcgg catgatagag taaattggtg ggggagagga cgtggcttac ccattctctg
    10621 acctgcggat gcgcgccgcg cggcgttctg gcgtcgaata gcaggtaata gcacccctct
    10681 tccagtcggc tttctatcgc tttttcaccg ccttgtattg gcccttccag catcaagccg
    10741 caggccggtt cttcactgat atccggcagt acccagacgt tcacttcgtc tatcaacgcc
    10801 cgatagccga agtaatcatc aaaggcgagt atcttgagct ggtttggcgt attacgccgc
    10861 acggcataag gcccggtgcc gatagggtgg ctggcgaaat tagccagcgt ttcccactcc
    10921 cgcggcaaaa tcatcgccgg gacctggccc agcagccacg gcaaccagcg atccggctgg
    10981 gaaagatgaa tatccagcgt ccacgcggta ggggagtcta tctttgtgat gtgcgagtaa
    11041 agcggaagcg tattgatacg cgtcagcgag gcgatgacat cttccatctc cagctcgcgg
    11101 ccatgatgaa aatgaatgcc ggggcgcagg tagaagcgcc acagtaaagg ggaaatttgc
    11161 tgccagtggt gcgcaatgtc cgcttccagt tccccgtttt cctcatttac ccgcgtgagc
    11221 gaactgaaaa tttgccgggc aatatgagtt tccgagcgac gtaatgcggt tcccggcagg
    11281 agattgtgca tcggacgata gtaaagaacc cgcagaatat gccgcccctg gcggaagctg
    11341 cgtcccagat gggaaatcag catttgcctg acagcgcttt tatcgccgac cagttgtacc
    11401 agttgatcga ttcgatcttg ttccagcagg tcttccgccc gctgctgttg cagcgccagt
    11461 ccggtataca ggaacgtcag acgcgaacgc tttccgcgtc cgacctcggc ttcccatgtt
    11521 agccaaccgc gcgcctgcat cgtatttagc agcgtacgca tatggcgacg cgaacagttc
    11581 agcagatccg ccagctcatt aagcgtggtg tcttgcgttt taccgtcaca acattgccag
    11641 agacggataa attgttgttg caggcgacct gagggcataa aaggggaact ccgatgaaaa
    11701 actcagcaat tttattatcc ctatattagg ccaataatat ctttcgatga agcaagagga
    11761 agaggtcact atgcgccagt tctggttgag atattttgcc gcgacggaaa aaacgtcctg
    11821 gctggcttgc ctgagcgcgc cgcagcgctt aaaaatgctc gcggaactga tgcagtggga
    11881 ggcgaccgat tgaagccaat tgcagacatc atgtgtgact gagtattggt gtaggcgata
    11941 gcctaaaatc acccgccagc agataatatc tgctggcttt tttatttcgg ctgtttctgg
    12001 atgacgacga tgggacggcg tctcaacggg atttctgcgg cggtttctgt ggtcacgcgg
    12061 gtgatgaccg ggcgagtaaa agacgtataa aaaatgccgg aatatccccg gcatgagcga
    12121 ctgatgagta accaggcgct tgatggcgct acgcttatca ggcctacaga atatagtggc
    12181 aacctggtga tattgcatac cctgtaggcc cggtaaggcg tgaaaggtta ccgcataaat
    12241 gccggttgtt tattttcgta ctcggcaatc gcgtcttcgt gctgcagcgt cagcccgatg
    12301 ctgtccagac cgttcaacat gcagtggcgg cggaagtcgt cgattttaaa actgtaggtc
    12361 ttatcgcctg ctttcaccac ctgtgcttcc agatccactt caaatttaat gcccggattg
    12421 gctttcacca gcgtaaacag ctcatcgacc tgttcgtcgc ttaacttcac cggcagcagt
    12481 tggttattga aactgttgcc gtagaagatg tcggcgaagc ttggcgcgat caccacttta
    12541 aaaccgtaat cggtcaacgc ccacggcgcg tgttcgcgtg aagagccgca gccaaagttt
    12601 tcccgcgcca acagtatcga cgcgccttga tattccggaa agttcaacac gaattccgga
    12661 tttggctgtt ggcccttttc gtccaggaaa cgccagtcgt taaacagatg ggcgccaaaa
    12721 ccggtgcgcg taaccttctg caaaaactgt ttagggataa ttgcatcggt atcgacgttg
    12781 gcggcatcca gtgggacaac caggccggta tgctgggtaa atttctctgc catggtagtt
    12841 tccttatttg atgctgcgaa tatcggcgaa gtggccggta acggcggcag cggcggccat
    12901 cgccgggctg actaaatgcg tgcgaccccc gcggccctga cgaccttcaa agttacggtt
    12961 gctggtggag gcgcagcgct cgcccgggtt caggcggtca ttattcatgg ccaggcacat
    13021 ggaacagcct ggtaagcgcc attcaaatcc tgcttcgata aagatcttgt ccagaccttc
    13081 cgcttccgcc tgcgctttca ccggacctga acccggcacc accagcgcct gcacgccagg
    13141 cgcaactttg cgccctttgg cgacttccgc cgccgcgcgc aaatcttcaa tacgcgaatt
    13201 ggtacaagag ccgataaaga ctttatcaat agcaacgtct gttaacggta cgcccggctg
    13261 taagcccata taagccagcg ctttttcggc gctggcgcgc tcaaccggat cgctaaaaga
    13321 ggcgggatcg gggatgatgt cggtgacgga aatcacctgg cccggattag tgccccaggt
    13381 cacctgcggc gcgatctctt ctgctcgcag ggtgacgaca gtatcaaagg tcgcgccgtc
    13441 atcggttttc agcgttttcc agtactcgac ggcttcgtca aaatcgcggc ccttcggcgc
    13501 gtgcaaacgc ccttttacgt agttgaaagt ggtttcatcc ggggcgacca gaccggcttt
    13561 ggcgcccatc tcaatcgcca tattgcacag cgtcatgcgg ccttccatac tcagcgcgcg
    13621 gatagcgtcg ccgcaaaatt caaccacgtg tccggtgccg ccggcgctac cagttttacc
    13681 gatgatcgcc agcacgatgt ctttggcggt aatgcccggt gcggcgttgc ccgtgacttc
    13741 aatcttcatg gttttagcgc gcccctgttt cagggtttgc gtcgccagta catgttctac
    13801 ctcagaagtg ccgatgccga aggccaacgc gccaaacgcg ccgtgggtag cggtgtggga
    13861 gtcgccgcag acgatggtca tacccggcag ggtaacgccc tgttccggcc ccatcacatg
    13921 gacgatgccc tgatatgggt gattcaggtc atacagctcg acgccgaact cgttacagtt
    13981 cttaatcagc tcttgcatct ggatacgcgc catttcacca gaagcattaa tgtctttagt
    14041 ctgcgtcgag acgttgtgat ccatcgtggc gaaggttttc cccggctgac gtaccggacg
    14101 atggtgcgcg cgcagaccgt caaacgcctg cggcgaggtc acttcgtgta ccaggtggcg
    14161 atcgatgtac agcagcggcg tttcgtttgg cgcctcaaag accacgtggg catcaaataa
    14221 tttttcgtat aacgttttgg ccatgattac accccttctg cgacatagcg ggcgataata
    14281 tcgcccatct catcggtact gactgcggca gcgcccctgg ctaaatcgct ggtgcgaacc
    14341 ccctcttcta atgcgcgatt gatcgcctgt tcaatggccg ttgccgcctc atcggcatcc
    14401 aggctgtagc gcagcagcag cgccagcgac aggatctgcg caattgggtt ggcgatattt
    14461 ttcccagcga tatccggcgc ggagccgcca gccggttcat acaggccaaa ctcttgctcg
    14521 ttcaggctgg cggagggcaa catccccatt gagccggtga tcatggcgca ttcgtcggac
    14581 agaatgtcgc cgaacaggtt agagcacagc aggacgtcaa actgcgacgg gtctttaatc
    14641 aactgcatgg tggcgttatc gatatacatg tgcgcgagtt ccacatcggg atacgctttc
    14701 gcgacatcat tgacgatctc acgccacagg atagagcttt gcagtacgtt ggctttatct
    14761 atagaggtga ctttacggcg gcgtttacgc gccgattcaa aggcgatacg ggcaatgcgc
    14821 tcgatctcaa agcggtgata aacttcggta tcaaaggctt tttcgtactg accgctgcct
    14881 tcacggcctt ttggctgtcc gaaatagatc ccgccggtca gctcgcgcac gcacaggata
    14941 tcgaaaccgt tagcggcgat atcggcgcgc aacgggcaaa atgcttccag tccctgatac
    15001 agtttcgccg gacgcaggtt actgaataat ttgaaatgtt tgcgcagcgg cagcagggcg
    15061 ccgcgctccg gctggctttc cgggggcaaa ttttcccatt tcgggccgcc gacggagcca
    15121 aacagaatgg catccgcctg ctcacaccct tcaacggtgg ctttcggcag tggatgacca
    15181 tgattgtcga tagcaatacc gccgacgtca tagcggctgg tggtgatacg catatcaaaa
    15241 cggctgcgta ccgcatccat aactttcagg gcttgcgcca tgacttccgg gccgataccg
    15301 tcgcccggca gtacggcaat atgatagttc ttcgacatta cacggtttcc ttgttgttct
    15361 ctttattttg agctttgcgt tgcaattctt tttcaacttc ggcggcgcgc cagatattgt
    15421 tcagtacgtg taccatcgct ttggcggagg attcgacgat atccgtcgcc agcccgacgc
    15481 cgtggaagcg gcgaccatga tggttcacga cgatatcgac ctgacccagc gcgtctttgc
    15541 cctggccttt ggcgttcagg tcgtatttaa ccaactcaac gtcgtagcca gtgatgcggt
    15601 taatcgcctg atagatggcg tcgaccgggc cgttgccgtt cgccgcctcg gccttgatct
    15661 cttcaccaca ggccagcttc acggaagcgg tggcgatatc gctggagccg gactgcacgc
    15721 tgaagtaatc cagacggaaa tgctctggtt cttcttgctg tttattaata aacgccagcg
    15781 cttccaggtc atagtcgaac acctggcctt ttttgtccgc cagcttcagg aacgcgtcgt
    15841 acaggtggcc catgttgtag tctgtgtcct tgtaacccat ctcttccatg cgatgtttca
    15901 cggcggcacg gccagagcgg gaggtcaggt tcagctgtat ctggttcaga ccgatggact
    15961 ctggcgtcat gatttcatag ttttcgcggt tcttgaggac gccatcctgg tggatgccgg
    16021 aagagtgggc aaaagcgccg ctgccaacaa tcgctttgtt ggccgggatc ggcatgttac
    16081 agatctggct gacggtctgg ctggtgcgcc agatttcgtg gtgattgatg ttggtgtgta
    16141 cgtttatgat gtctttgcgc actttaatcg ccatgatcac ctcttccagc gcgcagttac
    16201 cggcacgttc tccgataccg ttcatcgcgc cttcaacttg acgcgcgccc gcatgtactg
    16261 ccgccagcga gttgcctacc gctatcccta aatcgtcgtg ggtatgaacg gagatgatag
    16321 ctttgtcgat attggggaca cgttcataca gaccggaaat gattcccgcg aactcaaacg
    16381 gcatggtata gcccacggta tcgggaatat tgatggttct cgcgccggcg tttatagcgg
    16441 cttccaccac gcgcgccaga tcgtcaacag gcgtccggcc agcatcctcg caggagaact
    16501 ccacgtcatc agtgtaatta cgcgcccgct taaccatgta taccgcgcgt tcgatgacct
    16561 catccagcgt gctgcgcagc ttggtggcga tgtgcattgg cgaggtggcg ataaaagtat
    16621 ggatacgaaa cgcgtcggcg accttcagcg cctgtgccgc aacgtcgatg tctttttcta
    16681 cacaacgcgc cagggcgcaa acgcggctgt ttttgatggt gcgggcgatg gtttggacgg
    16741 attcaaaatc acccggagaa gagaccggga agcccacttc catgacatcg acacccatgc
    16801 gctcaagggc cagggcaatc tgcagcttct ctttcgcgct caggctggcc tgtaacgctt
    16861 gttcgccgtc gcgtaaggtc gtatcaaaaa taatgacttg ctggctcatg atgtggtcct
    16921 tgtctccagg ggcgccttgc gtcaggcata aaaaaacccg cacaacggcg cgggttttgt
    16981 ttgacttcga gctgacttaa tgttgaatgc cgcccaccgg tctaccgcgc acaataaatg
    17041 cgttgagtag tagtagccca gtgaaacgaa cgatatatga cattaattca gctccagcga
    17101 atgcgttatg cttttagtgg tactggatat gccgtttaat gtcaactcta ttttctgtcg
    17161 ccattgcatt ttgttgacga tatccggata cgtactttag ctaattgtgc tgggctgcgc
    17221 gtccaataaa ggataaaaga acgagtggac attcatactt ttcattgttt gaaatattta
    17281 ggcatttttg tttgc
//
LOCUS       DAJVBX010000091        17121 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.091, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000091 DAJVBX010000000
VERSION     DAJVBX010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 17121)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17121)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17121
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.091"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            71..325
                     /gene="bssS"
                     /locus_tag="OPV72_002526"
     CDS             71..325
                     /gene="bssS"
                     /locus_tag="OPV72_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460132.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm formation regulator BssS"
                     /protein_id="HCR9914790.1"
                     /translation="MEKNNEVIQTHPLVGWDISTVDSYDALMLRLHYQTPNRPEPEGT
                     EVGQTLWLTTDVARQFISILEAGIAKIESGDYQENEYRHH"
     gene            438..1556
                     /gene="solA"
                     /locus_tag="OPV72_002527"
     CDS             438..1556
                     /gene="solA"
                     /locus_tag="OPV72_002527"
                     /EC_number="1.5.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-methyl-L-tryptophan oxidase"
                     /protein_id="HCR9914791.1"
                     /translation="MKYDLIIIGSGSVGAAAGYYATRAGLKVLMTDAHMPPYQQGSHH
                     GDTRLIRHAYGEGEKYVPLVLRAQTLWDELSTHNEEPIFVRSGVVNLGPADSAFLANV
                     ARSAQQWQLNVERLDATALMTRWPEIRVPDNYIGLFEADSGFLRSELAITTWLRLARE
                     AGCAQLFNSPVSHIHHDDNGVTIETSEGCYHASKALISAGTWVKTLVPELPVQPVRKV
                     FAWFKADGRYSTKNRFPAFTGEMPNGDHYYGFPAENDELKIGKHNGGQRIQAPEERKP
                     FAAVASDGAEAFPFLRNVLPGIGGCLHGAACTYDNSPDEDFIIDTLPGHENTLVITGL
                     SGHGFKFAPVLGEIAADFALGKTPSFDLTPFRLSRFSQ"
     gene            1597..1710
                     /locus_tag="OPV72_002528"
     CDS             1597..1710
                     /locus_tag="OPV72_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceO family protein"
                     /protein_id="HCR9914792.1"
                     /translation="MRRLFHFLMNNIREHFMLYVILWSLLAVMDIVYLLFF"
     gene            1973..2545
                     /locus_tag="OPV72_002529"
                     /pseudo
     CDS             1973..2545
                     /locus_tag="OPV72_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460129.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b"
     gene            2542..3117
                     /locus_tag="OPV72_002530"
     CDS             2542..3117
                     /locus_tag="OPV72_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceI family protein"
                     /protein_id="HCR9914793.1"
                     /translation="MKKNLLGFTLASLLFTTGSAVAAEYKIDKEGQHAFVNFRIQHLG
                     YSWLYGTFKDFDGTFTFDEKNPSADKVNVTINTNSVDTNHAERDKHLRSAEFLNVAKF
                     PQATFTSTSVKKEGDELDITGNLTLNGVTKPVTLEAKLMGQGDDPWGGKRAGFEAEGK
                     IKLKDFNITTDLGPASQEVELIISVEGVQQK"
     gene            complement(3169..4221)
                     /locus_tag="OPV72_002531"
     CDS             complement(3169..4221)
                     /locus_tag="OPV72_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HCR9914794.1"
                     /translation="MPVLHNRISNDELKAKMLAESEPRTTISFYKYFTIASPQQTRDA
                     LYQVFTALDVFGRVYLAHEGINAQISVPQSKVETFRQQLYTFDPALDGVRLNIALEDD
                     GKSFWVLRMKVRDRIVADGIDDPSFDASNVGDYLKAADVNAMLDDPDAVFIDMRNHYE
                     YEVGHFENALEIPADTFREQLPKAVEMLREHADKKIVMYCTGGIRCEKASAWMKHNGF
                     NKVWHIEGGIIEYARRAREQGLPVRFIGKNFVFDERMGERISDEVIAHCHQCGVSCDS
                     HTNCKNDGCHLLFIQCPQCASKFNGCCSEQCCEELALPEEEQRRRRAGRENGNKIFNK
                     SRGRLNSKLSIPDPAE"
     gene            4441..5361
                     /locus_tag="OPV72_002532"
     CDS             4441..5361
                     /locus_tag="OPV72_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LpxL/LpxP family Kdo(2)-lipid IV(A)
                     lauroyl/palmitoleoyl acyltransferasee"
                     /protein_id="HCR9914795.1"
                     /translation="MTKLPKFSVALLHPRYWLTWLGIGALWLVVQLPYPVIYKLGCAL
                     GHLARRVMKRRAKIAYRNLELCFPEMSAQERHTMVVKNFESVGMGVMETGMAWFWPDR
                     RVNRWMEASGLEHIREVKAQGLGFILVGIHFLTLEFGARMFGMHNPGIGVYRPNDNPL
                     LDWLQTWGRLRSNKSMLDRKDLKGMVKALKSGELIWYAPDHDYGPRASVFVPLFAVDQ
                     AATTSGTWMLARMSKACIIPSVPRRKPDGKGYELIILPAEYSPPLESAEATAAWMNKI
                     VEQCIMMAPEQYMWLHRRFKTRPEGVPSRY"
     gene            5516..6730
                     /gene="mdtG"
                     /locus_tag="OPV72_002533"
     CDS             5516..6730
                     /gene="mdtG"
                     /locus_tag="OPV72_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdtG"
                     /protein_id="HCR9914796.1"
                     /translation="MSPSDVPINWKRNLTVTWLGCFLTGAAFSLVMPFLPLYVEQLGV
                     TGHSALNMWSGLVFSITFLFSAIASPFWGGLADRKGRKIILLRSALGMAIVMLLMGMA
                     QNIWQFLILRALLGLLGGFIPNANALIATQVPRHKSGWALGTLSTGGVSGALLGPLAG
                     GLLADHYGLRPVFFITASVLFICFLLTFFFIRENFLPVSKKEMLHVREVVASLKNPRL
                     VLSLFVTTLIIQVATGSIAPILTLYVRELAGNVSNIAFISGMIASVPGVAALLSAPRL
                     GKLGDRIGPEKILIVALIISVLLLIPMSFVQTPWQLALLRFLLGAADGALLPAVQTLL
                     VYNSTNQIAGRIFSYNQSFRDIGNVTGPLMGAAISASYGFRAVFCVTAGVVLFNAIYS
                     WNSLRRRRLAIE"
     gene            6812..7186
                     /locus_tag="OPV72_002534"
     CDS             6812..7186
                     /locus_tag="OPV72_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="secY/secA suppressor protein"
                     /protein_id="HCR9914797.1"
                     /translation="MTMYATLEEAIDAAREEFLADHPGLEQDEANVQQFNVQKYVLQD
                     GDIMWQVEFFADEGEDGECLPMLSGEAAQSVFDGDYDEIEIRQEWQEENTLHEWDEGE
                     FQLEPPLDTEEGRTAADEWDER"
     gene            complement(7187..7414)
                     /locus_tag="OPV72_002535"
     CDS             complement(7187..7414)
                     /locus_tag="OPV72_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceK/YidQ family lipoprotein"
                     /protein_id="HCR9914798.1"
                     /translation="MRIFAVSIMVITLSGCGSIISRTIPGQGHGNQYYPGVQWDMRDS
                     AWRYITILDLPFSLIFDTLLLPLDIHHGPYE"
     gene            complement(7488..10031)
                     /gene="mdoH"
                     /locus_tag="OPV72_002536"
     CDS             complement(7488..10031)
                     /gene="mdoH"
                     /locus_tag="OPV72_002536"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001044602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucans biosynthesis glucosyltransferase MdoH"
                     /protein_id="HCR9914799.1"
                     /translation="MNKTTEYIDALLLSEREKAALPKTDIRAVHQALDAEHRTYSRED
                     DSPQGSVKARLEHAWPDSLAKGQLIKDDEGRDQLQAMPKATRSSMFPDPWRTNPVGRF
                     WDRLRGRDVTPRYVSRLTKEEQASEQKWRTVGTIRRYILLILTLAQTVVATWYMKTIL
                     PYQGWALINPMDMVGQDIWVSFMQLLPYMLQTGILILFAVLFCWVSAGFWTALMGFLQ
                     LLIGRDKYSISASTVGDEPLNPEHQTALIMPICNEDVSRVFAGLRATWESVKATGNAA
                     HFDVYILSDSYNPDICVAEQKAWMELIAEVQGEGQIFYRRRRRRMKRKSGNIDDFCRR
                     WGNQYSYMVVLDADSVMSGECLSGLVRLMEANPNAGIIQSSPKASGMDTLYARCQQFA
                     TRVYGPLFTAGLHFWQLGESHYWGHNAIIRVKPFIEHCALAPLPGEGSFAGSILSHDF
                     VEAALMRRAGWGVWIAYDLPGSYEELPPNLLDELKRDRRWCHGNLMNFRLFLVKGMHP
                     VHRAVFLTGVMSYLSAPLWFMFLALSTALQVVHALTEPQYFLQPRQLFPVWPQWRPEL
                     AIALFASTMVLLFLPKLLSIMLIWCKGTKEYGGFWRVTLSLLLEVLFSVLLAPVRMLF
                     HTVFVVSAFLGWEVVWNSPQRDDDSTPWGEAFMRHGSQLLLGLVWAVGMAWLDLRFLF
                     WLAPIVFSLILSPFVSVISSRSTVGLRTKRWKLFLIPEEYSPPQVLVDTDKYLEMNRR
                     RILDDGFMHAVFNPSLNALATAMATARHRASKVLEIARDRHVEQALNETPEKLNRDRR
                     LVLLSDPVTMARLHYRVWNAPERYSSWVNHYQSLVLNPQALQGRTSSAG"
     gene            complement(10024..11559)
                     /gene="mdoG"
                     /locus_tag="OPV72_002537"
     CDS             complement(10024..11559)
                     /gene="mdoG"
                     /locus_tag="OPV72_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucans biosynthesis protein MdoG"
                     /protein_id="HCR9914800.1"
                     /translation="MMKMRWLGAAIMLTLYASSSWAFSIDDVAKQAQSLAGKGYEAPK
                     SNLPSVFRDMKYADYQQIQFNSDKAYWNNLKTPFKLEFYHQGMYFDTPVKINEVTATT
                     VKRIKYSPDYFNFGNVQHDKDTVKDLGFAGFKVLYPINSKDKNDEIVSMLGASYFRVI
                     GAGQVYGLSARGLAIDTALPSGEEFPRFREFWIERPKPTDKRLTVYALLDSPRATGAY
                     RFVIIPGRDTVVDVQSKVYLRDKVGKLGVAPLTSMFLFGPNQPSPTTNYRPELHDSNG
                     LSIHAGNGEWIWRPLNNPKHLAVSSYAMENPQGFGLLQRGREFSRFEDLDDRYDLRPS
                     AWITPKGDWGKGKVELVEIPTNDETNDNIVAYWTPDQLPEPGKEMNFKYTLTFSRDED
                     KLHAPDNAWVLQTRRSTGDVKQSNLIRQPDGTIAFVVDFVGADMKKLPPDTPVAAQTS
                     IGDNGEIVDSNVRYNPVTKGWRLMLRVKVKDAKKTTEMRAALVNADQTLSETWSYQLP
                     ANE"
     gene            11831..12985
                     /gene="mdoC"
                     /locus_tag="OPV72_002538"
     CDS             11831..12985
                     /gene="mdoC"
                     /locus_tag="OPV72_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucans biosynthesis protein MdoC"
                     /protein_id="HCR9914801.1"
                     /translation="MSSVPAPREYFLDSIRAWLMLLGIPFHISLIYSTHSWHVNSAAP
                     SWWLTLFNDFIHAFRMQVFFVISGYFSYMLFLRYPLKHWWKVRVERVGIPMLTAIPLL
                     TLPQFILLQYVKEKTENWPTLSAYEKYNTLAWELISHLWFLLVLVILTTVSIGIFTWF
                     QKRQETSKPRPAAISLAKLSLIFFLLGVAYAAIRRIIFIVYPAILSDGMFNFIVMQTL
                     FYVPFFILGALAFIHPDLKARFTTPSRGCTLGAAVAFIAYLLNQRYGSGDAWMYETES
                     VITMVMGLWMVNVVFSLGHRLLNFQSARVTYFVNASLFIYLVHHPLTLFFGAYITPHI
                     SSNLIGFLCGLIFVMGIALILYEIHLRIPLLKFLFSGKPPVKQESRAAIG"
     gene            complement(13002..14489)
                     /locus_tag="OPV72_002539"
     CDS             complement(13002..14489)
                     /locus_tag="OPV72_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706957.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase D family protein"
                     /protein_id="HCR9914802.1"
                     /translation="MMKKLPGFTQDYLLSKATTLPDKTRLERAVEPLCARHPGECGIL
                     ALDNSLDAFAARYRLTEMAARTLDVQYYIWEDDMSGRLLFSVLLSAAKRGVHVRLLLD
                     DNNTPGLDDTLRLLDSHPNIEVRLFNPFSFRTLRALGYLTDFARLNRRMHNKSYTADG
                     VVTLVGGRNIGDAYFGAGEEPLFSDLDVMAIGPVVNDVANDFERYWRCSSVSTLQQVL
                     SLSEQELTQRIELPESWYNDEITRRYLHKLETSQFMADLDRGTLPLIWAKTRLLSDDP
                     SKGEGKAQRHSLLPQRLFDVMGSPTERIDIISAYFVPTRAGVAQLLNLVRKGVKIAIL
                     TNSLAANDVAVVHAGYARWRKKLLRYGVELYELKPTREHETAVHDRGLTGNSGSSLHA
                     KTFSIDGSKVFIGSLNFDPRSTLLNTEMGFVIESETLATLIHKRFTQSQRDAAWQLRL
                     DRWGRINWIDRQQEEEKVLKKEPATRFWQRVLVRLAAILPVEWLL"
     gene            complement(14425..14964)
                     /gene="ymdB"
                     /locus_tag="OPV72_002540"
     CDS             complement(14425..14964)
                     /gene="ymdB"
                     /locus_tag="OPV72_002540"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetyl-ADP-ribose deacetylase"
                     /protein_id="HCR9914803.1"
                     /translation="MTSRLQVIQGDITQLSVDAIVNAANASLMGGGGVDGAIHRAAGP
                     ALLDACKLIRQQQGECQTGHAVITPAGKLSAKAVIHTVGPVWRGGEHQEAELLEEAYR
                     NCLLLAEANHFRSIAFPAISTGVYGYPRAQAAEVAVRTVSDFITRYALPEQVYFVCYD
                     EETARLYARLLTQQGDDPA"
     gene            complement(15052..15372)
                     /locus_tag="OPV72_002541"
     CDS             complement(15052..15372)
                     /locus_tag="OPV72_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HCR9914804.1"
                     /translation="MSVIKKNIPAIGLCICAFFIHSAVGQQTVQGGVIHFRGAIVEPL
                     CDISTHAENIDLTCLREGKKQMHRIDLRQASGLPQDIQSIATVRLHYLDAQKSLAVMN
                     IEYR"
     gene            complement(15504..15830)
                     /gene="csgC"
                     /locus_tag="OPV72_002542"
     CDS             complement(15504..15830)
                     /gene="csgC"
                     /locus_tag="OPV72_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli assembly protein CsgC"
                     /protein_id="HCR9914805.1"
                     /translation="MHTLLLLAALSNQITFTTTQQGDIYTVIPQVTLNEPCVCLVQIL
                     SVRDGVGGQSHTQQKQTLSLPANQPIELSRLSVNISSEDSVKIIVTVSDGQSLHLSQQ
                     WPPSAQ"
     gene            complement(15892..16347)
                     /gene="csgA"
                     /locus_tag="OPV72_002543"
     CDS             complement(15892..16347)
                     /gene="csgA"
                     /locus_tag="OPV72_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curlin major subunit CsgA"
                     /protein_id="HCR9914806.1"
                     /translation="MKLLKVAAFAAIVVSGSALAGVVPQWGGGGNHNGGGNSSGPDST
                     LSIYQYGSANAALALQSDARKSETTITQSGYGNGADVGQGADNSTIELTQNGFRNNAT
                     IDQWNAKNSDITVGQYGGNNAALVNQTASDSSVMVRQVGFGNNATANQY"
     gene            complement(16389..16844)
                     /gene="csgB"
                     /locus_tag="OPV72_002544"
     CDS             complement(16389..16844)
                     /gene="csgB"
                     /locus_tag="OPV72_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curlin minor subunit CsgB"
                     /protein_id="HCR9914807.1"
                     /translation="MKNKLLFMMLTILGAPGIATATNYDLARSEYNFAVNELSKSSFN
                     QAAIIGQVGTDNSARVRQEGSKLLSVISQEGENNRAKVDQAGNYNFAYIEQTGNANDA
                     SISQSAYGNSAAIIQKGSGNKANITQYGTQKTAVVVQKQSHMAIRVTQR"
BASE COUNT         4073 a         4535 c         4242 g         4271 t
ORIGIN      
        1 ttgcttcaga agaaaaacac gcattgaacc tcgagaaccg ttgtcttata acacgtacca
       61 ggggggcatg atggaaaaga ataatgaagt cattcagacc catccgcttg taggatggga
      121 catcagcacc gtcgatagct atgatgcgct gatgctgcgt ttacactacc agaccccaaa
      181 tcgtccggaa ccggaaggga ctgaagttgg tcaaacgctc tggttaacga cagatgtagc
      241 caggcaattt atttcaatat tagaagccgg catcgccaaa atagaatcag gcgattacca
      301 ggaaaacgag tatcgtcacc attagcgtga cgcgctcccc ctctctcagg caccgtaagg
      361 tgcctcactt atttctggct tgtatatctc agcgcagtta tttaccttga aatcatcgcg
      421 atagcagaga gaagctgatg aaatacgacc ttattattat cggcagcggt tcggttggcg
      481 ccgccgctgg ttattacgcc acccgcgccg ggctaaaggt cctgatgacc gatgcgcata
      541 tgccgcctta tcaacagggc agccaccacg gcgatacccg tcttatccgc cacgcttatg
      601 gtgaaggcga aaaatatgtc ccgctggtgc ttcgcgccca gacgctttgg gatgagctct
      661 ccacacacaa tgaagagcct atttttgtcc gctccggcgt cgtcaacctc ggcccggccg
      721 attccgcttt cttagccaac gtcgcacgaa gcgcgcaaca gtggcaattg aacgtcgagc
      781 gcctggacgc gacggccctc atgacgcgct ggccggaaat tcgcgtgccc gataattata
      841 tcgggctgtt tgaagctgac tccggtttcc tgcgcagcga attagccatt accacatggc
      901 ttcgtctggc ccgagaggca ggctgcgcac agctattcaa cagcccggta agccatattc
      961 accatgatga taacggtgtg acgatagaga cgagtgaagg ctgctaccac gccagcaaag
     1021 cgctgattag cgcgggcacc tgggtcaaaa cgctggtacc ggagctgccc gttcagcccg
     1081 tacgtaaagt ttttgcctgg tttaaggcgg atggacgtta cagcactaaa aaccgctttc
     1141 cggcctttac cggcgaaatg cccaacggcg atcactatta cggtttcccg gcggagaacg
     1201 acgagttaaa aatcggcaaa cacaatggcg ggcagcgaat acaggcaccg gaagagcgca
     1261 agccctttgc cgccgttgcc agcgatggcg cggaagcatt tcctttcctg cgtaacgtac
     1321 tgccgggtat cggcggttgt ttacatgggg cggcatgtac ctatgataat tcgccggacg
     1381 aggattttat tatcgatacg ctgcctggcc atgagaatac gcttgtcatc actggactca
     1441 gcggacatgg ttttaaattc gccccggtgt taggagaaat cgctgcggat tttgcgttgg
     1501 gaaaaacgcc ctcctttgat ctgacgccgt tccggctttc ccgttttagc caataatttg
     1561 tcggccccgt aaaggggctg tttattaagg taagctatgc gtcgtctctt tcattttctg
     1621 atgaataata ttcgcgaaca tttcatgctt tacgttattc tttggtcgct gctggcggtg
     1681 atggatattg tttatctcct tttcttctga ttgcttttca ttgacgttaa ctaacacttc
     1741 ctgaaagttc ctcacttttt atttcataat gttgaagcac ggcaataatg ccaactcctg
     1801 ccgttgtgcg gttacaggag tgaaatatct cgaaacttct gaagctgaat cgcaaacaac
     1861 atcaaaatta ttgaaataaa aataaatatc attcaaattc ttatttataa gttgcattcg
     1921 gcgcttttcc acgccatttt cattctctcg tgaaatattc attggtgtgt ttatgcaatt
     1981 taaaaatact ccacaacgtt atggcgtagt ttccgccgcc ctccactggc tgaccgccct
     2041 agtggtctat ggcatgtttg cgttgggttt atggatggtc acgctcagtt attacgacgg
     2101 ctggtatcac taggcgccgg aaatacataa aagtattggc atgttactga tgatggcgct
     2161 gatcgtgcgt attatctggc ggctttattc tccgccgccc gttgcgttga ccagctattc
     2221 ccgtttaacg cgcattggcg ccgccgcggg tcatatcctt ctgtatctcc tgctctttgc
     2281 gataatcatt agcggctacc tgatttccac cgccgacggt aaaccgatta gcgtctttgg
     2341 ctggtttgag attccggcca cgcttacgga cgcgggcgcg caggctgaca tcgccggaac
     2401 actgcatctg tggtttgcct ggtcgctggt cattatctcg ctctcgcatg gggttatggc
     2461 gctaaaacac catttcatcg ataaagacga cacactgaaa cgtatgacag gaatgtcgtc
     2521 atctgactat ggagctcaaa aatgaaaaaa aacctgctgg gattcaccct cgcatccttg
     2581 ttattcacga ccggttccgc cgtggcggcg gagtataaaa ttgataaaga aggccaacat
     2641 gcgttcgtca atttccgcat ccagcatctg ggctacagct ggctatacgg cacctttaaa
     2701 gatttcgacg gcacgttcac ttttgacgaa aaaaatccgt cagcagacaa agtgaatgtg
     2761 accattaaca ccaatagcgt cgacactaac catgccgaac gtgacaaaca cctgcgtagc
     2821 gcggagtttc ttaatgttgc gaaattcccg caggcaacct tcacctctac cagcgtgaaa
     2881 aaagagggcg atgaactgga tattaccggc aatctgacgc tcaatggcgt gactaaaccg
     2941 gtgacgctgg aagcgaagct gatgggccag ggcgacgatc cgtggggcgg taagcgcgcg
     3001 ggctttgagg ccgaaggaaa aattaagctg aaagatttca atataactac cgatctcggc
     3061 ccagcctcac aagaggtgga gcttatcatc tcagtagaag gcgttcagca gaagtaacgc
     3121 ctggcgaaat gccggatagc agcctttacg ccgctatccg gcaaaatatt actcagccgg
     3181 atcgggaatg ctcagtttgc tattaagccg accccgcgat ttattaaaaa ttttgttgcc
     3241 gttctcacga cccgcgcgac gtcggcgctg ttcttcctcc ggcaaggcca actcttcaca
     3301 gcattgttca ctacagcagc cgttaaattt actggcgcac tgcggacact ggataaacag
     3361 cagatggcaa ccgtcgtttt tgcagttggt atggctatcg caggacacgc cgcactgatg
     3421 gcaatgcgcg ataacctcat ccgagatgcg ctcgcccatt cgctcatcaa atacaaagtt
     3481 tttgccgata aagcgaacgg gaagcccctg ctcgcgcgcg cgacgggcgt actcaatgat
     3541 gccaccctca atatgccaga ctttattgaa accgttgtgt ttcatccagg cgctggcttt
     3601 ctcacaacga ataccgccgg tacagtacat cactatcttt ttatctgcat gttcccgcag
     3661 catttcaacc gcttttggca actgttcacg aaacgtatcc gccgggattt ccagagcatt
     3721 ttcgaaatgg ccgacttcat actcatagtg gttgcgcata tcaataaaga ccgcgtcagg
     3781 atcgtccagc atcgcattca catctgccgc cttcagataa tcgccgacat tactggcgtc
     3841 aaaactcgga tcgtcaatac cgtcagcgac gatacggtcg cgaactttca tacgcagcac
     3901 ccaaaatgac tttccgtcat cctccagcgc gatatttaaa cgcaccccgt ccagcgcggg
     3961 gtcgaacgta taaagctgtt gacgaaaggt ctcaaccttg ctttgcggca cgctgatttg
     4021 cgcattgatg ccctcatgcg ccaggtaaac gcgaccaaaa acgtccaacg ccgtaaacac
     4081 ctgatacaac gcgtcccgcg tctgttgcgg cgaggcgata gtgaaatatt tataaaaaga
     4141 aattgtcgta cgcggctcgc tttccgccag cattttggct ttcagctcgt cattagagat
     4201 gcggttgtgt aacactggca tggtgtacgt atcctgcaat cagcaaaaaa taaagtgggc
     4261 aggcatgata aggcaagtct cgccaattta catccacaca ttttgcgcta catttcctgc
     4321 tttacgctaa ataattaaca acaattgtcg atttaatcgc cactctcctg ctacatattt
     4381 ttgctcaacg caaaaagatg cgagaatacg gagaattgtt cgttgaaaga caggatagaa
     4441 atgacgaagt tgcctaagtt ctccgtggcc ttactgcacc cgcgctattg gttaacctgg
     4501 ttgggtatag gcgcgctttg gttggtcgtg caactcccct acccggtcat ctataaattg
     4561 ggttgcgcat tgggccacct ggcgcgacgc gtaatgaaac gccgcgcgaa aatcgcctat
     4621 cgcaaccttg aattatgctt tccggaaatg agcgcgcagg aacgccacac catggtggtc
     4681 aaaaactttg aatccgtcgg tatgggcgtg atggaaaccg gcatggcctg gttctggccc
     4741 gatcggcgag tgaaccgctg gatggaagcg agcggtctgg agcatatccg tgaagttaag
     4801 gcgcaggggc tggggttcat tctggtagga atacatttcc ttacccttga gtttggcgcc
     4861 cgcatgtttg gtatgcataa cccgggtatc ggcgtttatc gcccgaatga taatccgttg
     4921 ctcgactggt tacagacctg ggggcgctta cgctccaata aatcgatgtt ggatcgcaaa
     4981 gatctgaaag gtatggttaa ggcattgaaa agcggcgaat tgatctggta tgcgccggat
     5041 cacgattatg gcccgcgcgc cagcgtcttt gtaccgttat tcgccgtcga ccaggccgct
     5101 acgacctccg gtacctggat gctcgcgcgc atgtctaaag cctgtattat cccctccgtg
     5161 cctcgccgta aacccgacgg gaaaggctac gaactgatca tccttcctgc ggaatattcg
     5221 cctccgctgg agagcgcaga agcgactgcc gcatggatga ataagattgt tgagcagtgc
     5281 attatgatgg cgccagagca gtatatgtgg ctgcatcgcc gctttaaaac tcgccctgaa
     5341 ggcgtaccgt cgcgctattg acaggattgc agccgtcagg ctgcaatttt tcccctcttt
     5401 tagctttaaa agctccccac attgcgaggc tggtaaggtc ggcgcataat tataattagt
     5461 acgctcataa ttaaattgat gatagcgcaa aacgcgcatc atactgtgga acactatgtc
     5521 accctctgat gtccccataa actggaaacg caatctaacc gttacctggc tgggctgttt
     5581 tttaaccggc gcggcattca gtctggtcat gccttttctc cctctctacg ttgagcaact
     5641 cggcgtaaca ggccatagcg cgctcaacat gtggtccggg ctggtcttta gtattacgtt
     5701 cctcttttca gctatcgctt cccctttttg gggcggtctg gcggatcgta aagggcgtaa
     5761 gatcatactg ttgcgttccg ctctcggcat ggccattgtg atgctgttaa tgggcatggc
     5821 gcaaaatatc tggcaatttc tgatcctccg cgcgttatta ggcctgctgg gcggatttat
     5881 tcccaacgcc aatgcgctca tcgccactca ggtgccgcgc cacaaaagcg gctgggcgtt
     5941 agggacgctc tctactggcg gcgtcagcgg cgctctgctt ggcccacttg cgggcggtct
     6001 gctcgccgac cattacggcc ttcgcccggt cttttttatt accgccagcg ttttgtttat
     6061 ctgttttctg ctcaccttct tttttattcg cgagaatttc ctgccggtga gcaaaaaaga
     6121 gatgcttcac gttcgggaag tggtcgcctc gttaaaaaat ccccgcctgg tgttaagcct
     6181 gtttgtcacc acgctgatta ttcaggtggc gacggggtct attgcgccca tcctgacgct
     6241 ctatgtgcgc gaactcgcgg gaaatgtcag taatattgcg ttcattagcg ggatgatagc
     6301 gtccgttccc ggcgtggcgg cattacttag cgccccccgg ctcggcaagc tcggcgacag
     6361 aattggcccg gaaaagatcc ttatcgtcgc gctgattatt tccgtactgc tgctgattcc
     6421 aatgtctttt gtgcaaacgc cgtggcagct cgcgctattg cggtttctgc ttggcgcggc
     6481 ggatggcgcg ctgctgccag ccgttcaaac tctgctggtt tacaactcta ccaaccagat
     6541 agccgggcgc atattcagtt acaaccaatc tttccgcgat atcggcaacg tcaccggccc
     6601 tctcatgggt gccgcaattt ccgcgagcta tggcttccgc gccgtattct gcgtcacggc
     6661 aggcgtggtg ttgttcaatg ctatctattc atggaacagc ttacgacggc gcagactggc
     6721 aatagaatga tttttgcgct ttcatacttg caatatcaca gaatcagcta ttctttccct
     6781 aaatacctcg tcaaatcaaa gggagacact gatgaccatg tatgccacgc tggaagaagc
     6841 tatcgatgca gcccgggaag aatttctggc tgaccatcca ggcctcgaac aagacgaagc
     6901 gaatgtgcag cagttcaacg ttcagaaata tgtactgcag gatggggaca tcatgtggca
     6961 ggtcgaattt ttcgccgatg aaggtgaaga tggcgaatgt ctgccgatgc tgagtggtga
     7021 agccgcacag agcgtgtttg acggcgatta tgatgagata gagatccgcc aggaatggca
     7081 ggaagagaat actttgcatg aatgggatga aggggaattc cagcttgaac ccccgcttga
     7141 taccgaggaa ggccgtactg cggcagacga atgggatgag cgttaattac tcataaggcc
     7201 cgtggtgaat atcgagcggc agtagcagtg tatcgaagat cagtgagaag ggcagatcga
     7261 ggatagtgat atagcgccat gcggaatcac gcatatccca ctgcacgcca gggtaatact
     7321 ggttgccgtg tccttgtccg gggatcgttc tgctgataat actgccgcag ccgctcaggg
     7381 taatcaccat tatgctcacc gcgaatatac gcacctgata cctcatttca ctataaaaat
     7441 accggcatca cgccggtatt tttcacctca ctccagacct gaagacctta tcccgctgac
     7501 gatgttcgtc cctgcaacgc ctgcggattc aggacgagag actgataatg gtttacccag
     7561 gaagagtatc tctctggcgc attccagacc cgatagtgta aacgcgccat cgtcaccgga
     7621 tcgctgagca aaaccagacg ccgatcgcgg ttcagtttct ccggcgtttc gtttagcgcc
     7681 tgctccacat gacgatcgcg ggctatttcc agcaccttac tggcgcggtg acgcgcggtg
     7741 gccatcgcgg tcgccagcgc attaagcgac gggttaaata ccgcatgcat aaagccatcg
     7801 tccagaatac ggcggcgatt catctccaga tatttatcgg tatcgaccaa cacctgaggc
     7861 ggcgaatact cttccgggat caggaacagc ttccagcgtt tggtgcgtaa tcctaccgtt
     7921 gaacgactgg agatcaccga aacaaatggc gacagaatca gcgaaaagac aatcggcgcc
     7981 agccagaaca gaaagcgtaa atccagccac gccataccca ccgcccagac cagccccagc
     8041 agcagttgag agccgtgacg cataaaggct tctccccacg gcgtagaatc atcgtcgcgt
     8101 tgcggtgagt tccagaccac ttcccagccg aggaacgcgc tgaccacaaa cacggtatga
     8161 aacagcatac gcaccggcgc cagcaacacg gagaacagca cttccagcaa tagcgacagc
     8221 gtaacgcgcc agaaaccgcc atactctttg gtgcctttac accagatcag cataatactg
     8281 agcagcttcg gcaggaacag cagcaccatc gttgacgcaa acagcgcgat tgccagttcc
     8341 ggacgccact gcggccagac cggaaaaagc tggcgcggct gaaggaaata ttgcggctct
     8401 gttaacgcat gaacgacctg cagcgcggta gaaagcgcga ggaacataaa ccataacggc
     8461 gcggacaggt atgacattac cccggtcagg aacacggcgc gatgcaccgg gtgcattcct
     8521 ttcaccagga acagacgaaa gttcatcagg ttgccgtgac accagcggcg gtcgcgttta
     8581 agctcatcca gcaggtttgg cggcagctct tcataggagc cggggagatc gtaggcaatc
     8641 cagacgcccc accctgcccg acgcattagc gccgcctcca caaagtcgtg ggaaagaatc
     8701 gatccggcga acgaaccttc tcccggcagc ggcgccagag cgcagtgctc gataaacggc
     8761 ttcacgcgga taatggcatt gtgcccccag tagtgcgact cccccaactg ccagaagtgc
     8821 agcccggcgg taaacagcgg tccataaaca cgggtcgcga actgttggca gcgggcatac
     8881 agagtatcca tccccgacgc tttcggcgaa gactggataa tcccggcgtt agggttcgct
     8941 tccatcaggc gcaccagccc gctcagacac tcgccgctca tcactgagtc cgcgtccagc
     9001 accaccatat agctgtactg attgccccag cggcggcaaa aatcgtcaat attgccgctt
     9061 ttgcgtttca tacggcggcg gcggcgacgg taaaaaattt ggccttcgcc ctgcacttcc
     9121 gcgatgagct ccatccacgc cttttgctcc gccacgcaga tatccgggtt ataactatcg
     9181 ctaaggatat agacgtcaaa atgcgcggcg ttgcctgtgg ctttaacgga ctcccaggtc
     9241 gcgcgcagac cggcgaaaac gcggctaacg tcttcattac agataggcat gatcagcgcc
     9301 gtctggtgtt ccggattgag gggctcatcg ccaaccgtag acgcggagat actgtactta
     9361 tcgcgcccga taagcagttg caggaagccc atcagcgccg tccagaatcc ggcagacacc
     9421 cagcagaaca gcacggcaaa caaaatcagg ataccggttt gcagcatgta gggcaggagc
     9481 tgcataaagg agacccaaat atcctgcccc accatatcca taggattgat gagcgcccat
     9541 ccctgatagg gcagaatggt cttcatatac caggtcgcga cgacggtttg cgccagagtc
     9601 aaaattaaca aaatatagcg gcgtatagtg ccgacggtac gccatttttg ctcactcgcc
     9661 tgctcttctt ttgtcagacg agaaacatag cgcggcgtta catcccgccc acgcaggcga
     9721 tcccagaaac ggccaaccgg gttggttcgc cagggatcag gaaacatcga agagcgcgtc
     9781 gcttttggca tagcctgcaa ctgatcgcgc ccttcatcat ctttaattaa ctgccccttc
     9841 gccaatgaat ccggccaggc gtgttcaagg cgggctttta cggaaccctg cggtgaatcg
     9901 tcttctcgcg agtaagtccg atgctcggca tccagcgcct gatgcacggc gcggatgtca
     9961 gttttcggca atgccgcttt ctcacgttca gaaagcagca gtgcgtcaat atactcagtt
    10021 gttttattca ttggcaggta actggtagct ccaggtttca cttagcgtct gatcggcatt
    10081 caccaatgcg gcacgcattt ccgtggtttt cttcgcgtct ttgactttca cgcgcagcat
    10141 taaacgccag cctttagtga ctgggttata gcgtacatta ctgtcaacga tttcaccgtt
    10201 atcgccaatg ctggtttgtg cagcgacggg cgtatccggc ggcagttttt tcatgtcggc
    10261 gccaacgaaa tccaccacaa aggcaatagt gccgtcgggc tggcgaatca gattcgactg
    10321 tttaacgtcg cccgttgagc ggcgtgtttg cagcacccag gcattatccg gcgcatgaag
    10381 tttatcttca tcgcggctga aggtcagagt gtacttgaag ttcatctctt tacccggttc
    10441 cggcagttga tccggagtcc agtaagcgac gatgttatcg ttggtttcat cattggtcgg
    10501 aatttcaacc agttcaacct tacctttgcc ccagtcgcct ttcggggtaa tccaggcgct
    10561 tggacgcagg tcatagcgat cgtctaaatc ttcaaagcgc gagaactcgc gaccacgctg
    10621 caacaggccg aatccctgag ggttttccat cgcatagctg ctcacagcga ggtgttttgg
    10681 attgttcagc ggacgccaaa tccactcgcc attacccgca tgaatggata agccgttcga
    10741 gtcatgcaat tccggacgat agttggtcgt cggcgacggc tggtttggcc caaacaggaa
    10801 catactggtt aatggcgcaa cgcccagctt gcccacctta tcgcgcagat agacttttga
    10861 ctgcacgtcc accacggtat cgcggccagg aatgatcaca aaacggtaag cgccggtcgc
    10921 gcgcggagaa tccagtaatg catagacggt caaacgctta tcggtgggtt ttggacgctc
    10981 aatccagaac tcgcgaaagc ggggaaactc ttcaccagat ggtaaggcgg tatcaatcgc
    11041 caggccgcgc gcagataagc catacacctg gcctgcgccg ataacgcgga aatagctggc
    11101 gccaagcata ctgacgattt cgtcgttctt atctttactg ttaatggggt acaggacttt
    11161 gaacccggcg aagcctaaat cttttaccgt gtctttatcg tgctgaacat tgccaaaatt
    11221 gaagtaatcc gggctgtatt tgattctttt gaccgtcgtc gccgtcactt cgttaatctt
    11281 gaccggcgta tcgaagtaca tcccctgatg gtaaaattcg agcttaaaag gggtctttaa
    11341 gttgttccag taggctttat cgctgttaaa ctggatctgc tgataatccg catatttcat
    11401 gtcgcggaaa acggagggca agttgctttt aggcgcctca tagcctttcc cggctaaaga
    11461 ttgagcttgt tttgccacgt catcaatact gaacgcccag ctcgatgatg cgtagagcgt
    11521 taacataata gctgcgccca accaacgcat tttcatcatt tgtcgtttat gtttcataat
    11581 aagtaagcac ttcccccttt gtgtgcttat atcgatccga tccattttaa tggataatca
    11641 ggcattacga caactgaatc caggctttgt tcagcgcgct ggctcatgga ttaagcacct
    11701 cccgcgcctg ttttcacttt gcgtgcttat cctggagaca ggttgtcgga gttggtgtag
    11761 ggttgctacc gaatgtaact ataattcgcc ttatggataa ggtgaaaaat ctgagaatac
    11821 gtgaccttat atgagctctg tacccgcgcc gcgtgaatat tttcttgact ctatccgcgc
    11881 atggctgatg ttgttaggga ttccctttca tatctcgttg atctattcca ctcacagttg
    11941 gcatgtcaat agcgccgcgc catcgtggtg gctaaccctg tttaacgatt ttatccacgc
    12001 ttttcgtatg caggtgtttt ttgttatttc tggttatttt tcgtacatgt tatttttacg
    12061 ttatccatta aaacactggt ggaaagtacg ggtagaacgt gtgggtattc ccatgcttac
    12121 cgcaatccct ttgcttacct tgccgcaatt tatcctgttg caatatgtca aagagaaaac
    12181 agagaactgg cctacactct ctgcctatga aaaatataat acgttagcgt gggaactcat
    12241 ttcacatctg tggtttttac tggtgctggt gatattaacc accgtcagca tcgggatttt
    12301 tacctggttc caaaaaaggc aggaaacaag caagcctcgt cccgccgcta tttcgctggc
    12361 caaactttcg cttatttttt tcctgctggg ggtggcgtac gctgctatca ggcgcattat
    12421 attcatcgta tatccggcaa tcctcagtga cggcatgttc aattttattg tgatgcaaac
    12481 gctattttat gtgccgtttt ttattctcgg cgcgttggcc ttcattcacc ccgatctgaa
    12541 agcgcgcttc accacgccct cacgcggatg cactttaggc gctgccgttg cttttatcgc
    12601 gtatctgctg aatcaacgtt atgggagcgg cgacgcctgg atgtacgaaa ccgaatccgt
    12661 gattacgatg gtaatggggc tatggatggt gaacgtggta ttttcactgg ggcatcgctt
    12721 gttaaacttt cagtccgcgc gtgtcaccta tttcgtgaat gcttcgctgt ttatttatct
    12781 ggtgcatcat cccttaacgc ttttctttgg cgcgtatatt acaccgcata tctcctccaa
    12841 cctgatcggg ttcttgtgcg ggctgatatt tgttatgggt attgcgttaa ttctgtatga
    12901 aattcattta cgcatcccgc tcctgaaatt tctcttttca ggtaaaccgc cggtaaaaca
    12961 agaaagccgc gccgcgatcg ggtagttttc cgcgcgcggg ttcacagcaa ccattccaca
    13021 ggtaaaattg ccgccaaccg taccagaact cgctgccaga aacgcgtagc gggttctttc
    13081 tttaacacct tttcctcttc ttgctgacga tcgatccagt taattcgtcc ccagcgatcc
    13141 agccgcagtt gccaggccgc atcgcgttgg ctctgcgtaa aacgcttatg aataagcgtc
    13201 gccagcgttt cactttcaat gacaaagccc atttcggtat ttaaaagcgt tgaacgggga
    13261 tcaaaattaa gcgacccgat aaacacctta ctaccatcaa tactgaacgt tttagcatgt
    13321 aagctggaac ctgagttccc ggtgagtccg cgatcatgta cggcggtttc atgttcgcgg
    13381 gtcggtttca gttcgtagag ctccacgcca tagcgcagta atttcttgcg ccagcgcgcg
    13441 taccctgcgt gaacgaccgc cacatcgttg gccgccagag agttagttaa gatggcgatc
    13501 ttcacacctt tcctgaccag attaagcaac tgcgccacgc ctgcgcgcgt agggacaaag
    13561 taagcggaaa taatgtcgat acgctccgtc ggcgacccca tcacgtcaaa taatcgctgc
    13621 ggaagaagcg aatggcgctg cgccttcccc tcgcctttag aagggtcatc gctaagcaag
    13681 cgtgtttttg cccaaatcag cggcaacgtt ccgcgatcga gatccgccat aaactggctg
    13741 gtttccagct tatgcagata acggcgggtg atctcatcgt tataccagga ttcgggaagt
    13801 tcgatacgct gcgtcagttc ctgctcagaa agggataata cttgctgcaa tgtcgacact
    13861 gaactacagc gccagtaacg ttcaaaatca ttggcgacat cattgaccac cgggccaatg
    13921 gccatcacgt ccagatcgga aaatagcggc tcctcgccag cgccgaaata ggcatcgccg
    13981 atgttgcgcc caccgaccag cgtcactacg ccgtcggcag tgtaactttt attgtgcatc
    14041 cgccgattca gccgcgcaaa atccgtcaaa tatcccagcg cgcgtagcgt acgaaaagag
    14101 aaaggattaa acagacgaac ttcgatatta ggatggctat ccagcaagcg caacgtatca
    14161 tccagaccag gcgtattgtt atcatccagc agcagacgaa catgaacgcc gcgcttcgcc
    14221 gccgacagca gaaccgaaaa gagcagccgc ccggacatat cgtcttccca aatataatac
    14281 tgcacatcca gcgtccgcgc cgccatttcg gtcaggcggt agcgggcggc aaaagcgtcc
    14341 agactgttat ccagcgcaag aatgccgcac tctccgggat ggcgcgcgca tagcggttca
    14401 acggcacgct ccaggcgtgt tttatcaggc agggtcgtcg ccttgctgag taagtaatct
    14461 tgcgtaaagc cgggcagttt cttcatcata acagacaaag tatacctgtt caggcagagc
    14521 gtaacgggta ataaaatctg aaaccgtcct gacggcgact tcagcggcct gggcgcgtgg
    14581 atagccataa acgccggtac tgattgccgg aaaagcgatg gaacgaaagt gattcgcctc
    14641 ggcaagcagc aaacaattcc ggtatgcctc ttcgagtagc tcagcttcct ggtgttcgcc
    14701 gcctcgccag acgggcccca ctgtgtgaat aaccgccttt gccgaaagct tgccagcagg
    14761 cgtgataacc gcatgtcccg tctgacattc gccctgttgc tgacggatga gtttacaggc
    14821 gtccagcaat gccggccccg ccgcgcgatg aattgcgccg tctacgccac cgccgcccat
    14881 taatgatgcg ttagcggcat tcacaatcgc atcgacgcta agttgagtga tatcaccctg
    14941 tatgacctga agacgtgatg tcataacccc ccccttttgt ctcaccttat ctgcaaagtg
    15001 tacagcaggg ctttcaacag agtcgctctt tttatatcta tgacaccgcc gttaacggta
    15061 ctcaatattc atcaccgcca ggcttttttg cgcatcgaga taatgcagcc gtaccgtcgc
    15121 aatggactga atatcctgcg gtaatccaga tgcctgccga aggtctatcc ggtgcatttg
    15181 ctttttacct tcgcgtaggc aggttaaatc aatattttcg gcgtgagtag aaatatcgca
    15241 cagtggctca acaatcgcgc cgcgaaaatg gataacgccg ccctgtaccg tttgttgccc
    15301 taccgcagaa tggataaaaa aagcgcagat acacaggcct atggcaggga tatttttctt
    15361 gattacggac atgttaactc ctcaatgatt agtcatcctc gagggttcgg cgttaccttt
    15421 tagcgacatg ccgagacgat gagacgcttt tatcgcctct ttaataccca ggtcagccaa
    15481 tccatttccg ccaccatcaa aaactactgt gcagaaggcg gccattgttg tgataaatgc
    15541 agtgattgtc cgtccgaaac agtaacaata attttaaccg agtcctctga agatatattt
    15601 acactaagac gagacaactc aatcggttga ttagcaggta aagatagcgt ttgtttttgc
    15661 tgtgtatggc tttgtccccc gacgccgtcg cgcacagaga gaatttgcac cagacagacg
    15721 cagggttcgt ttaatgtgac ctgagggatc accgtgtaaa tatcgccttg ctgagtcgtg
    15781 gtaaacgtaa tctgatttga aagtgcggca aggagcaata aagtatgcat aatttcctcc
    15841 cgaaaaaaaa cagggcttac gccctgtttt tttattagcg cagacgctaa attaatactg
    15901 gttagccgtg gcgttgttgc caaaaccaac ctgacgcacc attacgctgg aatcagatgc
    15961 ggtctgatta accagcgcgg cgttattacc gccgtattga ccgacagtaa tatcggagtt
    16021 tttagcgttc cactggtcga tggtggcatt gtttctgaaa ccattctgag tcagttcaat
    16081 agtactgtta tccgcaccct ggcctacatc ggcgccgtta ccataaccgc tctgggtaat
    16141 ggtcgtttca gatttacggg catcgctttg cagagcaagc gcagcgttag cggaaccgta
    16201 ctgataaatg ctcaacgtgg aatccggccc ggaactattg ccgccgccgt tatgattacc
    16261 gccgccgccc cattgtggaa cgacgccagc cagagcactg ccagaaacta cgattgctgc
    16321 gaatgctgcc acttttaaaa gtttcatggt aaaaccccca tcggattgat ttaaaagtcg
    16381 taacggtatt agcgttgggt gacgcgaata gccatatgcg actgtttctg cactacaact
    16441 gctgttttct gcgtaccgta ctgggtaata ttggccttat ttccagaacc tttctggata
    16501 atagccgcac tattaccgta agcgctttgc gatatactgg catcgttggc attgcccgtt
    16561 tgctcaatat acgcaaagtt ataattccct gcctggtcga ctttcgcccg attattttct
    16621 ccttcttgtg aaataacgga caatagtttt gatccttcct ggcgtactct ggcactatta
    16681 tccgtgccga cttgaccaat aatggccgcc tgattaaatg aagacttgct taattcattt
    16741 accgcaaaat tatactctga acgagccaga tcataatttg tcgcggttgc aatcccaggc
    16801 gcacccagta ttgtcaacat cataaataac aatttgtttt tcatgctgtc accctggacc
    16861 tggtcgtaca tagcgaaaat tatctattac cttgttagcg acatgcgttt tttgttaacg
    16921 cgtcgttacg atgaagagta tgtccgtgga aacattttta ataactcacc cacgcgtggt
    16981 attttgttat ttaagctcat accaaagtgc taataaaacg atagccatgt gattttttat
    17041 aattgatttt tggccacaga agatagtgta tcgcgcacct aaaaaatgaa gtgttggtgt
    17101 gtgttatgcc gccatgggga t
//
LOCUS       DAJVBX010000092        16845 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.092, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000092 DAJVBX010000000
VERSION     DAJVBX010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 16845)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16845)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16845
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.092"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(127..3240)
                     /gene="acrD"
                     /locus_tag="OPV72_002545"
     CDS             complement(127..3240)
                     /gene="acrD"
                     /locus_tag="OPV72_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease AcrD"
                     /protein_id="HCR9914808.1"
                     /translation="MANFFIDRPIFAWVLAILLCLTGALAIFSLPVEQYPDLAPPNVR
                     ITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSQSSGTGQATITLSFIAGTDPDE
                     AVQQVQNQLQSAMRKLPQAVQDQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVAS
                     NIQDPLSRVNGVGDIDAYGSQYSMRIWLDPAKLNSFQMTTKDVTDAIESQNAQIAVGQ
                     LGGTPSVDKQALNATINAQSLLQTPQQFRDITLRVNQDGSEVKLGDVATVELGAEKYD
                     YLSRFNGNPASGLGVKLASGANEMATAKLVLDRLNELAQYFPHGLEYKIAYETTSFVK
                     ASIIDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINT
                     LTMFAMVLAIGLLVDDAIVVVENVERIMSEEGLTPREATRKSMGQIQGALVGIAMVLS
                     AVFVPMAFFGGTTGAIYRQFSITIVSAMVLSVLVAMILTPALCATLLKPLHKGEQHGQ
                     RGFFGWFNRTFNRNAERYEKGVAKILHRSLRWILIYVLLLGGMVFLFLRLPTSFLPQE
                     DRGMFTTSIQLPSGSTQQQTLKVVEKVENYYFTHEKNNIMSVFSTVGSGPGGNGQNVA
                     RMFVRLKDWDARDPTTGSSFAIIERATKAFNQIKEARVFASSPPAISGLGSSAGFDME
                     LQDHAGAGHDALMAARDQLIELAGKNSSLTRVRHNGLDDSPQLQIDIDQRKAQALGVS
                     IDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAKYRMLPDDINLWYVRNKDGGMVP
                     FSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDVMESLVHQLPGGFGLE
                     WTAMSYQERLSGAQAPALYAISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLAT
                     WMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQKGHALLDATLYASRQRLRPI
                     LMTSLAFIFGVLPMATSTGAGSGSQHAVGTGVMGGMISATILAIFFVPLFFVLIRRRF
                     PLKPRPE"
     gene            complement(3425..5125)
                     /gene="narQ"
                     /locus_tag="OPV72_002546"
     CDS             complement(3425..5125)
                     /gene="narQ"
                     /locus_tag="OPV72_002546"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite two-component system sensor
                     histidine kinase NarQ"
                     /protein_id="HCR9914809.1"
                     /translation="MTVKRPVSASLAKAFFYIVLLSILSTGSALLTLTSSLRDAEAIN
                     IAGSLRMQSYRLGYDLQSRSPQINAHRQLFQHALNSPVLQNLNAWYVPQAVKTRYARL
                     HANWLEMNSRLQDGDIVWYQSNINNYVDQIDLFVLALQHYAERKVMLVVAISLAGGIG
                     IFTLVFFTLRRIRQQVVRPLNQLVTASQRIEHGQFAPLPLDTSLPNELGLLAKTFSQM
                     SSELHKLYRSLEASVEEKTHDLHEAHRRLEVLYQCSQALNTSQIDVHCFRHILQIVRE
                     HDAAWYLELTVGDNWRISEGTQSPDLPMQMLPVTMQDTVYGELHWQSPNVNASTPLLN
                     SVSTMLGRGLYFNQAQKHFQQLLLMEERATIARELHDSLAQVLSYLRIQLTLLKRAIP
                     EDNAGAQSIMADFSRALNDAYRQLRELLTTFRLTLQQADLPSALHEMLEDLQSQTPAK
                     LKLDCRLPTLALDAQMQVHLLQIVREAVLNAIKHANASEIAVSCVTAPDGDHTVYIRD
                     NGIGIGEPHEPAGHYGLNIMRERAERLGGTLNFSQPSGGGTLVSISFRSSNKEESQLT
                     "
     gene            5311..7170
                     /locus_tag="OPV72_002547"
     CDS             5311..7170
                     /locus_tag="OPV72_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase FeS-binding subunit"
                     /protein_id="HCR9914810.1"
                     /translation="MNRFIMANSQQCLGCHACEVACVMAHNDERHVLTPQRYQPRITV
                     IKHQRQRSAVTCHHCEDAPCARSCPNGAIAHINDSVQVNAQKCIGCKSCVVACPFGTM
                     QMVLTPVAPNQFKASAHKCDLCQGREQGPACVENCPADALQLVTEDSLTRLAKTRRLR
                     TARQEIRPWHTVDTQHSGTACSKVERMQATPPRGEPDKLAIEARKTTFEEIYLPFRAA
                     QAEREAARCLTCGEHSICEWTCPLHNHIPQWIELVKAGDIDAAVELSHQTNCLPEITG
                     RVCPQDRLCEGACTLRDEYGAVTIGNIERYISDRALSKGWRPDLSDVQKSDKRVAIIG
                     AGPAGLACADVLARRREIFSAMGIRFELNCEVGKDISLETLLESYDAVFVGVGTYRSM
                     KADLPNEDAPGVYDALPFLIANTKQVMGLPALPDEPFIDTAGLNVVVLGGGDTAMDCV
                     RTALRHGAANVTCAYRRDEANMPGSKKEVKNAREEGANFEFNVQPVELVLDTHGRASG
                     IRFLRTRLGEPDGQGRRRPVPVPDSEFVMPADAVIMAFGFHPHGMSWLESHGVKVDNW
                     GRIAASVESEFRYQTSNPKIFAGGDAVRGADLVVTAMAEGRHAAQGILDWLAK"
     gene            complement(7619..8917)
                     /gene="pbp4b"
                     /locus_tag="OPV72_002548"
     CDS             complement(7619..8917)
                     /gene="pbp4b"
                     /locus_tag="OPV72_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin binding protein PBP4B"
                     /protein_id="HCR9914811.1"
                     /translation="MKFTLVATVLLTFSLSAFAVEYPVLTTASPDQVGFDSQKLHRLD
                     GWIQNQIDAGYPSINLLVIKDNHIVLQKAWGYAKKYDGSTLLAHPIRATTNTMYDLAS
                     NTKMYATNFALQKLVYEGKIDVNDLVSKYIPGFKDMPGDKIKGKDKLRIIDILHHVAG
                     FPADPQYPNKNVAGKLFSQSKSTTLEMIKKTPLEYQPGSKHIYSDVDYMILGFIIESI
                     TAMPLDRYVETTIYKPLGLKHTVFNPLMKGFTPPQIAATELHGNTRDGVIHFPNIRTN
                     TLWGQVHDEKAWYSMGGVSGHAGLFSDTHDMAVLMQVMLNGGGYGNVKLFDNKTVAQF
                     TRRSPEDATFGLGWRVNGNASMTPTFGVLASPQTYGHTGWTGTLTSIDPVNHMAIVIL
                     GNRPHSPVANPKVNPNVFVSGLLPAATYGWIVDQIYGSLK"
     gene            9121..9696
                     /gene="nudK"
                     /locus_tag="OPV72_002549"
     CDS             9121..9696
                     /gene="nudK"
                     /locus_tag="OPV72_002549"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose pyrophosphatase NudK"
                     /protein_id="HCR9914812.1"
                     /translation="MSQTITLIKDKILSDNYFTLRNITYDLTRRNGEVIRHKREVYDR
                     GNGATILLYNSTKKTVVLVRQFRVATWVNGNQDGMLIETCAGLLDNDEPEVCIRKEAI
                     EETGYDVGEVRKIFELYMSPGGVTELIHFFIAEYHDSERASIGGGVEDEEIEVLELPF
                     SRALEMVRSGEIRDGKTVLLLNYLQTSHLMD"
     gene            9821..10864
                     /locus_tag="OPV72_002550"
     CDS             9821..10864
                     /locus_tag="OPV72_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1176 domain-containing protein"
                     /protein_id="HCR9914813.1"
                     /translation="MRYRVILFCLFGLLPVQLLWAAPAQRTFSDWQVTCNNQNFCVAR
                     NTGEHHGLVMTLSRSAGARTDAVLRIDRGGLAPPDAKEAAIAPRLLLDGKPLSFNSSH
                     WRVSPWHLMTGDPATITAFLQTIQDAQAITLKNGVQTLSLAGLKAALLFIDAQQKRVG
                     SETAWIEKGNEPPLSVPPAPALKGIAVINPTPVPLSEEERDDLLDYAAWRVNGIRCSL
                     DPLRRETQVSALTDDKALLIVNCEAGAYNTIDLAWVVSRKKTLVSRAVRLRLPFNRGV
                     ESNDMELMNAFFDEKTRELVTLAKGRGLTDCGIQTRWRYDGDRFRLVRYAEEPSCDSW
                     HGPDAWPTLWITR"
     gene            10992..11222
                     /locus_tag="OPV72_002551"
     CDS             10992..11222
                     /locus_tag="OPV72_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914814.1"
                     /translation="MKINNGPVLCPHCGCLSAYYEIDRLAAIREKVNKEGGSAAWDST
                     LQAHKKKAFCLMCHKSIDEVVIGQSDAPESTK"
     gene            complement(11285..13285)
                     /gene="tkt"
                     /locus_tag="OPV72_002552"
     CDS             complement(11285..13285)
                     /gene="tkt"
                     /locus_tag="OPV72_002552"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HCR9914815.1"
                     /translation="MSRKDLANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWNDFL
                     KHNPTDPTWYDRDRFILSNSHASMLLYSLLHLTGYDLPLEELKNFRQLHSKTPGHPEI
                     GYTPGVETTTGPLGQGLANAVGLAIAERTLGAQFNRPDHEIVDHYTYVFMGDGCLMEG
                     ISHEVCSLAGTLGLGKLIGFYDHNGISIDGETEGWFTDDTAKRFEAYHWHVVHDIDGH
                     APEAVKKAILEAQSVKDKPSLIICRTVIGFGSPNKAGKEESHGAALGEEEVALTRQKL
                     GWHHPAFEIPKEIYRAWDGREKGEKAQQQWQEKFAAYEKAYPELAAEFTRRMSGGLPE
                     AWESATQKFINDLQANPAKIATRKASQNTLNAYGPLLPELLGGSADLAPSNLTIWKGL
                     TSLKEDPAGNYIHYGVREFGMTAIANGIAHHGGFVPYTATFLMFVEYARNAARMAALM
                     KARQIMVYTHDSIGLGEDGPTHQAMEQLASLRLTPNFSTWRPCDQVEAAVGWKLAIER
                     QHGPTALILSRQNLAQVERTPEQVKAIARGGYILKDSGGKPDIILIATGSEMEITLQA
                     AEKLTGEGHNVRVVSLPSTDIFDAQDEAYRESVLPAHVTARVAVEAGIADYWYKYVGL
                     KGAIIGMTGYGESAPADKLFPYFGFTVENIVEKARRVLNIKG"
     gene            complement(13305..14255)
                     /gene="tal"
                     /locus_tag="OPV72_002553"
     CDS             complement(13305..14255)
                     /gene="tal"
                     /locus_tag="OPV72_002553"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase"
                     /protein_id="HCR9914816.1"
                     /translation="MNQLDGIKQFTTVVADSGDIESIRHYQPQDATTNPSLLLKAAGL
                     EQYGHLIEDAIAWGKKHGGTQEQQVAAASDKLAVNFGAEILKSIPGRVSTEVDVRLSF
                     DKEKSIEKARHLVDLYQQQDVDKSRILIKLAATWEGIRAAEQLEKEGINCNLTLLFSF
                     AQARACAEAGVYLISPFVGRIYDWYQARSPLEPYVVEEDPGVKSVRNIYDYFKQHRYE
                     TIVMGASFRRTEQILALTGCDRLTISPNLLKELKEKEEPVIRKLVPSSQMFHRPTPMT
                     EAEFRWEHNQDAMAVEKLSEGIRLFAVDQRKLEDLLAAKL"
     gene            14527..16806
                     /gene="maeB"
                     /locus_tag="OPV72_002554"
     CDS             14527..16806
                     /gene="maeB"
                     /locus_tag="OPV72_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxaloacetate-decarboxylating
                     malate dehydrogenase"
                     /protein_id="HCR9914817.1"
                     /translation="MDEQLKQSALDFHEFPVPGKIQVSPTKPLATQRDLALAYSPGVA
                     APCLEIEKDPLAAYKYTARGNLVAVISNGTAVLGLGNIGALAGKPVMEGKGVLFKKFA
                     GIDVFDIEVDELDPDKFINVVAALEPTFGGINLEDIKAPECFYIEQKLRERMNIPVFH
                     DDQHGTAIISTAAILNGLRVVEKNISDVRMVVSGAGAAAIACMNLLVALGMQKHNIVV
                     CDSKGVIYKGREPNMAETKAAYAVDDSGKRTLDEVIDGADIFLGCSGPKVLTQEMVKK
                     MARAPMILALANPEPEILPPLAKEVRPDAIICTGRSDYPNQVNNVLCFPFIFRGALDV
                     GATAINEEMKLAAVRAIAELAHAEQSEVVASAYGDQDLSFGPEYIIPKPFDPRLIVKI
                     APAVAKAAMDSGVATRPIADFDAYIDKLTEFVYKTNLFMKPIFSQARKDPKRVVLPEG
                     EEARVLHATQELITLGLAKPILIGRPSVIEMRIQKLGLQIKAGVDFEIVNNESDPRFK
                     EYWSEYYQIMKRRGVTQEQAQRAMIGNHTAIGAIMVQRGEADAMICGTIGDYHEHFSV
                     VKAVFGYRDGVHTAGAMNALLLPSGNTFIADTYVNEDPTPEQLAEIAVMAAETVRRFG
                     IEPKVALLSHSNFGSSNSLSASKMRETLERVRERAPDLMIDGEMHGDAALVESIRNDR
                     MPDSPLKGAANILVMPNMEAARISYNLLRVSSSEGVTVGPVLMGVSKPVHVLTPIASV
                     RRIVNMVALAVVEAQTTPL"
BASE COUNT         3896 a         4429 c         4626 g         3894 t
ORIGIN      
        1 tatcgaagtc atgcttcgta aataaatgcc tggaaggcac cgcgctccca taggggataa
       61 gaaaaggcga ctcaacgaaa gtcgcctttt ttgtgcccga cacctcgtat caggctggcc
      121 aggagcttat tccgggcgcg gcttcagcgg gaagcggcga cgtatcagca cgaaaaacag
      181 gggtacaaag aagatagcca gaatggttgc tgagatcatt ccccccatca cgccggttcc
      241 gacagcatgt tggctacccg agcctgcccc ggtgctggtg gccatcggca atacgccaaa
      301 gataaacgcc agcgaagtca tcagtatcgg tcgcaggcgc tggcggctgg cgtacagcgt
      361 ggcgtctaac agcgcgtgtc ccttctgatt catttcgttg gcgaattcca caatcagaat
      421 cgcgtttttc gccgagaggc cgataacggt caacagcccc acctggaagt aaacatcgtt
      481 ttccagcccg cgcatccagg tggcgagtaa cgcgccgatg accccgagcg gcacaaccag
      541 catcaccgag aagggcaccg accagctttc atacaatgcc gccagacaca ggaagacgac
      601 taatagcgaa atagcgtaca gcgcaggcgc ctgcgcgccg gagagccgtt cctggtaaga
      661 catggctgtc cattccaggc caaaaccgcc cggtagctga tgcaccaacg actccatgac
      721 atccatcgcc gtcccggtac tgacccccgg cgcggcctct ccgacaattt ctaccgccga
      781 atagccgtta tagcgttcca gacgcggcga tccggtttcc cagcgcgagg tggcgaaggc
      841 ggagaagggg accatgccgc cgtctttgtt acggacatac caaagattaa tatcgtccgg
      901 caacatacga tatttcgctg cggcctgaac atagaccttc ttcacgcggc cccggtccat
      961 aaagtcgttg acgtagctcg atccccaggc tgtttgcagg gtgtcgttga tatcgtcaat
     1021 cgatacgccc agcgcctgcg ctttccgttg gtcaatatca atttgcagtt gcgggctgtc
     1081 gtccaggccg ttgtggcgca cgcgggtcaa ggaactgttt ttcccggcca gctcaatgag
     1141 ttgatctcgt gcggccatca gcgcgtcatg gcctgctccg gcgtgatcct gtaattccat
     1201 atcaaaaccg gcggagctgc ccagaccgct aattgccggc gggctgctgg cgaagacgcg
     1261 agcttcttta atctggttaa atgcttttgt cgcccgctca ataatggcga acgaggagcc
     1321 ggtggtggga tcgcgcgcgt cccagtcttt caagcgaaca aacatacgcg cgacgttttg
     1381 cccgttcccg ccagggccgg aaccgaccgt cgagaagacc gacataatgt tgtttttctc
     1441 atgggtgaag taatagtttt caaccttttc aacgactttc agggtctgct gttgcgtaga
     1501 gccgctcggt agctggatag acgtagtgaa catgccccga tcttcttgcg gcagaaagga
     1561 ggtggggaga cgcaaaaaca ggaacaccat gccgccaagc aacagaacat aaatcagaat
     1621 ccagcgcagg ctgcgatgca aaattttcgc tacgcctttc tcataacgtt cggcattacg
     1681 attgaaggta cggttaaacc agccgaaaaa tccgcgttgc ccgtgctgtt cgcctttgtg
     1741 cagcggtttt aataacgttg cgcacagcgc cggcgtcagg atcatggcga ccagcaccga
     1801 cagcaccatt gccgagacaa tggtgataga aaactgacga taaatcgccc cggtggtacc
     1861 gccaaagaac gccatcggta cgaataccgc agacagcacc atcgcgatac cgaccagcgc
     1921 cccctggatt tgtcccatgg atttgcgcgt cgcttcacgc ggcgtgagcc cttcttcgct
     1981 catgatacgt tcgacgtttt ccaccaccac gatggcatcg tcgaccagga gcccgatcgc
     2041 cagcaccatc gcgaacatgg ttaatgtgtt aatactgtag ccgaacgcgt aaagcacgga
     2101 gaaggtgccc attaatacta ctggcacggc gatcgtcgga atgagcgtgg cgcgaaagtt
     2161 ttgcaggaac agatacatca ccaggaaaac cagcgcgata gcttccagca acgttttgac
     2221 cacatcgata atcgaggctt tgacaaagga ggtggtttca tacgcgatct tgtattccag
     2281 gccgtgaggg aagtactgcg ccagctcgtt gaggcgatcc agtaccagct tcgcggtcgc
     2341 catttcgttc gcgccggagg ccagcttaac gccaaggccg gaagccggat tgccgttaaa
     2401 acggctgagg tagtcatatt tttccgcccc cagctccacg gtggcgacat cgcccagttt
     2461 gacctcggaa ccgtcctgat taacgcgcag ggtgatatcg cgaaattgtt gcggcgtttg
     2521 cagcagcgac tgcgcattga tggtggcgtt cagcgcctgc ttgtcgaccg aaggcgtacc
     2581 gccaagctgc ccgacggcga tttgcgcatt ctgcgactca atcgcatcgg tcacgtcttt
     2641 cgtggtcatc tgaaaactat tcaatttggc cggatcgagc cagatacgca tagagtactg
     2701 tgaaccataa gcgtcaatat cgcccacgcc gttgacgcgg ctgagcgggt cctgaatatt
     2761 actggcgacg tagtcggcga tatcctgctt gtccatagaa ccgtcggtag agacgaaagc
     2821 gatggtcaaa atattggtat cgcccgtttt gcgtaccgtg acgccttgat cctgtaccgc
     2881 ctgcggcagt ttacgcatcg cggactgtaa ctggttttgc acctgctgaa ccgcctcatc
     2941 aggatcggtt cccgcaatga agctcagcgt aatggtcgcc tgtccggttc cgctgctttg
     3001 tgatgacatg tacatcagat tatcgaggcc cgtcatattc tgctcaataa cctgggttac
     3061 ggtattttcc agcgtttgcg ccgacgctcc cggataattc gcggtaatac gtacgttggg
     3121 cggcgccaga tcgggatatt gttcaacagg taaagaaaaa atggctaacg cccctgtcag
     3181 acacaacagg atagccagca cccaggcaaa aatggggcga tcgataaaaa aattcgccat
     3241 taaaggggaa cctcgtgttt ctacatatcg ttatagattt gaactgcttc actgtagcgg
     3301 caagctacga gccaaacgtg gagaaataaa ggagataatg taaattatca tgcgctttta
     3361 cagcatactt tttgtgccaa cgccggaaag cctgacatct ggccttccgg tgatttgccg
     3421 ttctttacgt taactgactc tcttccttgt tggaggagcg aaaactgata ctgaccagcg
     3481 tgccgccgcc ggagggttgc gaaaaattca gcgtgccgcc aagccgttcc gcgcgctcac
     3541 gcattatatt cagaccatag tgtccggcag gctcatgcgg ttcgccgata ccaatgccat
     3601 tatcgcgaat ataaacggta tgatcgccgt caggcgcggt gacgcagctc acggcgattt
     3661 cgctcgcgtt ggcgtgttta atggcgttca ggacagcttc acgcacaatt tgcaataaat
     3721 gcacctgcat ttgcgcatcc agcgccagcg tgggtaaacg gcaatccaac ttgagtttag
     3781 ccggagtctg actctgtaaa tcttccagca tctcatgcaa tgcggagggt aaatcggcct
     3841 gctgtaacgt cagacggaac gtggtgagta gctcgcgaag ctgacggtag gcgtcgttca
     3901 gcgctctgga aaaatccgcc atgatgcttt gcgcgccggc gttatcttct ggaatggcgc
     3961 gcttcaaaag cgttaattga atacgtaaat aagaaagtac ctgcgccagc gaatcgtgta
     4021 actcacgggc aatcgtcgcg cgctcttcca ttaacaaaag ttgctggaag tgtttttgcg
     4081 cctgattaaa gtacaaacca cgccccagca tcgtggagac gctgttcagc aacggcgtag
     4141 aggcattaac gttggggctt tgccagtgga gttcgccata gaccgtgtcc tgcatcgtca
     4201 ctggcagcat ttgcatcggc aggtcggggc tttgcgtgcc ttcgctaatc cgccagttat
     4261 cgcccacggt taactccaga taccaggcgg cgtcatgttc acggacaatt tgcaaaatat
     4321 ggcgaaaaca gtggacatcg atttggctgg tattcagcgc ctgggagcac tggtataaca
     4381 cctccaggcg gcggtgcgct tcgtgcagat cgtgcgtttt ttcttccacc gaggcttcca
     4441 gcgaacgata aagtttatgc agctcgctcg acatctgact aaacgttttc gccaacaatc
     4501 ccagctcatt gggtaagctg gtatccagcg gcagcggggc gaactgacca tgttcaattc
     4561 gctgactggc ggtgaccagt tgattcagcg ggcgaacgac ctgctggcga atacgccgta
     4621 gggtaaaaaa gaccagcgta aatatgccga taccgcccgc cagcgatatg gcgacgacca
     4681 gcatgacttt acgctcggcg taatgctgta acgccagaac gaagagatca atttgatcga
     4741 cgtaattgtt gatattggac tgataccaga caatgtcgcc atcctgtagg cggctattca
     4801 tctccagcca gttggcgtgc aggcgcgcgt agcgagtttt caccgcctgc ggcacatacc
     4861 aggcgttgag attttgcagt accggcgagt tgagcgcgtg ctggaaaagt tgacgatgcg
     4921 cattaatctg cgggctacgg ctttgcagat cgtaacccag ccgatagctc tgcattcgta
     4981 gcgaaccggc gatattgatc gcttcggcat cccgtaaact gctggtcagc gtcagtaatg
     5041 cgctgccggt ggacagaata gacaacagca caatatagaa aaaagcctta gccagactgg
     5101 ccgagaccgg gcgtttaacc gtcacactgg tactccccgc atttagctga accgcaattt
     5161 catttgcttt gaaataaatt gatctgccac aggttctgga cagatagttg tgcttcctgg
     5221 gcagatgaac attgccgacc ccgccttcgt cagttaataa caatgctcat ataaagaata
     5281 aggtttttgc aaccaaaaca gaaggacgcc atgaatcgtt ttattatggc caatagccag
     5341 cagtgtctgg gatgccatgc ctgcgaggtc gcctgcgtaa tggctcacaa tgatgagcga
     5401 catgttctga cgccacagcg ctatcagccc cgaattactg tcatcaaaca tcagcgccag
     5461 cgcagcgcgg ttacatgtca ccattgcgaa gatgcgccct gcgcccgtag ctgtccgaac
     5521 ggcgcgatcg cgcatattaa cgacagcgtg caggtcaatg cgcagaagtg catcggctgt
     5581 aagtcctgcg tcgtcgcctg cccattcggc accatgcaga tggtattgac gcccgtcgcg
     5641 ccaaaccagt tcaaagccag cgcgcataaa tgcgatctgt gtcagggacg tgaacagggt
     5701 ccggcctgtg tggaaaattg cccggcggat gcgctgcaac tggtcaccga agactcgttg
     5761 acccgtctgg ctaaaacgcg acggctgcgt accgcccggc aggagattcg cccctggcat
     5821 accgtggata cacaacacag tgggacagca tgcagcaaag tcgagcgtat gcaggcgacg
     5881 ccgccgcgcg gcgaaccgga taaactggcg attgaagcgc gtaaaaccac ctttgaggaa
     5941 atttatctgc cgtttcgcgc cgcgcaggcg gagcgtgaag cggcccgctg cctcacatgc
     6001 ggggaacaca gtatctgcga atggacctgt ccgctgcata accatattcc ccagtggatc
     6061 gaactggtga aagccggcga tattgatgcg gcggtagagc tttcccacca gaccaactgt
     6121 ctgccggaaa ttaccgggcg cgtctgtccg caggatcggc tatgcgaagg cgcgtgtaca
     6181 ctccgcgatg agtatggcgc ggttaccatc ggcaacattg agcgctatat ctccgatcgc
     6241 gctctgagca aaggctggcg tcccgacctg tcggacgtac agaagagcga taagcgcgtg
     6301 gcgattatcg gcgcggggcc ggcaggtctt gcctgcgctg acgtgctggc gcgccgtcgg
     6361 gaaatcttca gcgcgatggg gattcgtttc gaacttaact gcgaagtagg gaaagatatt
     6421 tctctggaga cgctgctgga gagttatgac gccgtctttg tcggggtagg aacctatcgt
     6481 tccatgaagg ctgatttacc gaatgaagac gcgccggggg tatatgatgc gttgccattc
     6541 ctcatcgcca ataccaaaca ggtgatgggg cttccggcgt tgcctgacga gccgtttatt
     6601 gatactgcgg gccttaacgt ggttgtgctg ggcggcggtg acaccgcaat ggactgcgta
     6661 cgtacggcgt tgcgtcatgg cgctgccaac gtcacctgcg cttatcgccg cgatgaggcc
     6721 aatatgccag ggtcgaaaaa agaggtgaaa aacgcgcggg aagagggcgc gaactttgaa
     6781 tttaacgttc agccagttga gttggtgctg gatacgcacg ggcgcgccag cggtattcgc
     6841 tttttgcgta cgcggcttgg cgaaccggat ggtcaggggc gacgccgtcc ggtacctgta
     6901 ccggacagcg agttcgtgat gccggcggat gcggtcatta tggcgtttgg ttttcatccg
     6961 catggtatgt cgtggctgga atcgcatggc gtgaaggtgg ataactgggg acgtattgcc
     7021 gccagcgtcg agagcgagtt tcgttaccag acgtccaacc cgaaaatttt cgctggcggc
     7081 gatgcggtgc gcggcgccga tctggtggtg acggcgatgg cagaaggccg acatgccgcg
     7141 caggggatac tcgactggtt agctaaataa gcgtatttgt aggccggtta aggcctggaa
     7201 cggttaaatg atttagtgat aaaaaatctt aaacttattg gctaacctta ctccgtttgc
     7261 agaaatgttg acgctcgcag ggctggacgc cctgcgataa acattttccc gctgggtcga
     7321 tgtttaacag gcctgataag gtcaatctta gtattgaaaa tagagtgtaa attgaaggaa
     7381 gggacgctat cagaatccct tcttagagcc tatcccatta gggctatttt acgtgccatt
     7441 ttggacctgg gcagtgctcg ccaaaacgcg ttagcgtttt gaacgccgct tgcggcggcc
     7501 cgaaggacga gcgtagcgag tcaaacctca cgtactacgt gtacgctccg gtttttgcgc
     7561 gctgtccgtg tccaaactgg ctgcgccaat aacgtctggt gggataggct cttaattttt
     7621 attttaagga accatatatc tggtcaacaa tccagccata cgtcgccgca ggtaataatc
     7681 cactgacaaa aacattcggg ttcactttag gatttgctac cggcgagtgc ggcctgttac
     7741 ctaaaataac aatcgccata tgattaaccg gatcgataga cgtcagcgtt ccggtccatc
     7801 cggtatgtcc atacgtttgc ggactggcta ataccccgaa cgttggggtc attgaggcgt
     7861 tgccgttaac gcgccacccc agaccaaagg tagcatcttc tggcgagcgg cgagtaaact
     7921 gcgcaaccgt tttgttgtcg aatagcttca cgttaccgta gccgccccca ttgagcatga
     7981 cttgcattaa cacagccata tcatgggtgt cagaaaacag tccggcgtgt cctgaaacgc
     8041 cgcccattga gtaccaggct ttttcgtcat gcacctggcc ccatagtgta ttggtgcgaa
     8101 tattggggaa atgaatcacg ccgtcacgcg tgttgccgtg tagttccgtt gcggcgattt
     8161 gcggcggcgt gaagcctttc atcagcgggt taaagacggt atgttttaat ccgagcggtt
     8221 tataaatggt ggtttcgacg tagcgatcta atggcattgc cgttatcgat tcaatgataa
     8281 aaccaagaat catataatcc acgtcgctgt agatatgctt cgacccaggt tgatattcca
     8341 gcggtgtctt tttaatcatc tccagagtag tgcttttact ctgtgaaaat aatttaccgg
     8401 cgacgttttt attgggatat tgtgggtcgg caggaaagcc cgcgacgtga tgaagaatat
     8461 caataatgcg gagtttatct ttgcctttta ttttatcccc aggcatatcc ttaaagccgg
     8521 ggatatattt tgataccaaa tcattgacat ctatttttcc ttcatacacc agtttttgca
     8581 atgcaaagtt agtggcatac atttttgtgt ttgaagccag gtcatacatc gtgttagtgg
     8641 tcgcccgaat gggatgggct aacagcgtgg aaccgtcata ttttttggca tagccccagg
     8701 ctttttgtag aacaatatga ttatctttta tcaccagaag attgatgctg ggatatccgg
     8761 catcaatttg attttgaatc cagccatcaa gtcggtgaag tttttggcta tcaaacccca
     8821 cctgatcagg gctcgcggtg gtcaataccg gatactcaac ggcaaaagct gaaagggaaa
     8881 acgtcagtag aaccgtcgca acgagagtaa atttcatgat gattccctca gtctcactcc
     8941 ggccgtcaaa tcatatcgcg agcatggact ctgcggcccg gagaagcaga atgtggtcat
     9001 ggcagtgaca gaaaaatatg gctgtacatc cgttcagtcg gcattaagga ttaacccttc
     9061 agcagacaaa accgacctca cggcgtaata ttaatgctct ttttacaccc tggagccagc
     9121 atgtcgcaaa ccattacgct tattaaggat aaaattcttt ctgataatta ttttactctg
     9181 cgcaacatta cctatgacct gacccgtcgt aatggcgagg ttatccgtca caagcgtgag
     9241 gtttacgatc gcgggaatgg cgcaaccatt ctgctttaca actcaactaa aaaaaccgtg
     9301 gttctggttc gccagtttcg cgtggcgaca tgggtcaatg gtaatcaaga cggtatgtta
     9361 attgaaacct gcgctggcct gcttgataac gacgagccgg aggtctgtat ccgtaaagag
     9421 gccattgaag agacagggta tgacgttggt gaggtacgca agatatttga gctgtatatg
     9481 tcgccaggcg gcgtcacgga gctgattcat ttcttcattg ccgaatatca tgatagcgag
     9541 cgtgccagca tcggcggcgg cgtggaggac gaagagattg aggtgcttga actaccgttt
     9601 tcccgggcgc tggaaatggt gcgctcaggc gagattcggg acggtaagac cgtgttattg
     9661 cttaactatt tacagacgtc tcatctaatg gactgaaaaa aaagaaatat atttctttac
     9721 acaaaaaaga ccaatccgat aaatctgatt gagaaccctg aggcgcgcaa ggaagatacc
     9781 gcctgagctg tgttgttctg aatctggggt tgttccgttc atgcgctacc gcgttattct
     9841 tttttgtctg tttggcctgt tgccggtcca gctactgtgg gctgcgccag cgcaacggac
     9901 tttttccgac tggcaggtca cctgcaataa ccaaaatttt tgcgtagcgc gcaatactgg
     9961 cgaacatcat gggctggtga tgacattaag ccgcagcgcc ggggcgcgta ccgatgcggt
    10021 actgcgtatc gaccgcggcg gtttggcgcc gcccgacgct aaagaagccg caattgcgcc
    10081 tcgcttattg ctggatggca aaccgctttc gttcaacagt tcacactggc gcgtgtcgcc
    10141 ctggcatctc atgaccggcg atcctgccac catcaccgca tttttacaga cgattcagga
    10201 tgcgcaggcc atcaccttaa aaaacggcgt tcagacgctt tcgctggcgg gattaaaagc
    10261 ggcattactg tttatcgacg cgcaacaaaa acgtgtgggc agcgaaaccg cctggattga
    10321 aaaaggaaac gaaccgccgc tcagcgtgcc cccggcaccg gcattaaagg ggatcgccgt
    10381 tattaatcca acgcccgtac cgctgagtga ggaagaacgc gacgatctgc tggactacgc
    10441 cgcatggcgg gtaaacggca ttcgttgttc gcttgacccg ctgcgtcgcg agacgcaggt
    10501 cagcgcgttg acggatgata aagcgttatt gattgttaac tgcgaagccg gcgcctataa
    10561 cactattgat ctcgcctggg tagtttcacg caaaaaaacg ctcgtctcgc gcgccgtacg
    10621 tttgcggctg ccgtttaatc gcggcgtcga aagtaatgac atggagttga tgaacgcctt
    10681 ctttgacgag aaaacgcgcg agctggtgac gttggcgaaa gggcgggggt taaccgactg
    10741 tggtatccag acgcgctggc gctatgatgg cgatcgtttt cgtctggtac gttatgccga
    10801 agaaccgagc tgcgatagct ggcacgggcc ggatgcctgg cctacgctgt ggatcacgcg
    10861 ttgaatcctg gttgttatcc ccttttcaga atagggatac acctattgag gtttcattta
    10921 tggtatagag attgctacgt tacggtagga ttgttacttt acccgatagc ctcaccacag
    10981 caggaaatag tatgaaaata aataatggcc ccgtattatg cccccattgt ggctgcctga
    11041 gcgcttatta tgaaatagat cggctggcgg cgataagaga aaaagtgaat aaagaaggcg
    11101 gatcagcggc gtgggattca acattgcagg cgcataaaaa aaaggccttt tgcctgatgt
    11161 gccataaatc cattgatgag gtcgtcatcg ggcagtcaga tgcgcctgag tctacgaagt
    11221 aattttgcac agcctacaga acaggtctgc agactgtgca aagtctgtgt tgctaacgcc
    11281 cgccttagcc tttgatgttc agcacccggc gggctttttc cacaatattt tccacggtaa
    11341 agccaaaata cgggaacagt ttgtcagccg gggcggattc accgtatccc gtcatgccga
    11401 taattgcgcc ttttaggcca acatatttat accagtagtc ggctataccg gcctccaccg
    11461 cgacgcgggc ggttacgtgc gccggtagca ctgattcgcg atatgcctcg tcctgcgcat
    11521 cgaaaatatc cgttgaaggc aacgacacca cccgaacgtt atgcccctcg ccagtcaatt
    11581 tttccgccgc ctggagggta atttccattt ccgatccggt agcgatcaga atgatatccg
    11641 gcttgccgcc gctatctttc agaatataac cgccgcgggc aatcgctttc acctgttccg
    11701 gcgtgcgttc cacctgcgcc agattctgcc gcgagagaat caacgccgtc ggcccgtgct
    11761 gacgttcaat ggccagcttc caaccgactg ccgcctcaac ctgatcgcag ggacgccagg
    11821 tgctgaagtt aggcgttaag cgcaggctcg ccagttgttc catggcctgg tgcgtcgggc
    11881 catcttcgcc caaaccgatg gagtcgtggg tatagaccat aatctgccgg gctttcatta
    11941 aggccgccat acgcgccgcg ttacgcgcat attcgacaaa catcagaaac gtggcggtat
    12001 acggtacaaa gccgccgtgg tgggcgatgc cgttggcaat ggcggtcatg ccgaattcgc
    12061 gcacgccata gtggatgtaa ttacctgccg gatcctcttt caacgaggtc aaacctttcc
    12121 agatagtcag gttgctcggc gccagatccg ccgatccgcc caacagttcc ggcaacaggg
    12181 gaccataggc attgagcgta ttttgcgatg ctttacgggt ggcgattttg gccggattag
    12241 cctgcaagtc gttaataaat ttttgcgtgg cggattccca tgcctccggc aatccgccgc
    12301 tcatccggcg ggtaaactcc gcggccagct caggataagc cttctcataa gcagcaaact
    12361 tttcctgcca ctgctgctgc gctttctcgc ctttttcacg gccatcccac gcgcggtaaa
    12421 tctcttttgg gatctcaaac gccggatgat gccatcccag cttctggcgg gtcagcgcca
    12481 cctcttcttc gcccagcgcc gcgccgtgcg actcctcctt cccggcttta ttcggcgagc
    12541 caaaacctat caccgtccga cagataatta gcgaaggttt atcttttacg ctctgggctt
    12601 ccagaatggc ttttttcacc gcctccggag cgtgcccgtc aatgtcatgc acgacatgcc
    12661 agtggtaggc ttcaaaacgt ttggctgtat cgtcggtaaa ccagccttcg gtttcgccat
    12721 caatggagat gccgttgtga tcgtaaaagc cgatcagttt gcccagtccc agcgtaccag
    12781 ccagcgaaca cacctcatgc gagatcccct ccatcagaca gccgtcgccc ataaagacat
    12841 aggtgtagtg gtcgacaatc tcatggtccg gccggttgaa ctgtgcgcct aacgtacgct
    12901 cggcaatcgc cagcccgacg gcattcgcca gcccctggcc cagcggcccg gtggtggttt
    12961 caacgccagg cgtatagcca atctccgggt gaccaggcgt tttagagtgc agttgacgga
    13021 agttttttag ctcctccagc ggcaggtcat acccggttaa atgcagcaga ctatagagca
    13081 gcatggaggc gtgactgttg gaaaggataa aacgatcacg gtcataccag gtcggatcgg
    13141 tggggttatg tttaagaaaa tcgttccata gcacttcagc gatatccgcc atccccatcg
    13201 gcgcgccggg gtgcccggaa ttggcttttt gaacggcatc catgctcagc gcacgaatcg
    13261 cattggcaag gtctttacgg gacataaatc actccatgca aggtttatag tttggcggca
    13321 agcaggtctt ccagtttgcg ctggtcaacg gcgaaaaggc ggataccttc cgacagcttc
    13381 tctacggcca tcgcgtcctg attatgttcc cagcggaact ccgcttccgt cattggcgta
    13441 ggacggtgga acatctgcga ggaaggcacc agtttacgga tcaccggttc ttctttttct
    13501 ttcagctctt taagcaggtt aggggagata gtcagtcgat cgcagccggt tagcgcgagg
    13561 atttgctcag tacggcggaa acttgcaccc atcacgatgg tttcatagcg atgctgttta
    13621 aagtaatcgt agatattgcg taccgatttc acgccgggat cttcctccac gacatacggc
    13681 tccagcggac tacgcgcctg ataccagtcg taaattcggc ccacgaacgg agagattaaa
    13741 tagacgcccg cttcggcgca ggcgcgcgcc tgggcaaaag agaacaacaa cgtcaggttg
    13801 caattaatgc cttctttttc gagctgttcg gcggcgcgaa taccttccca ggtcgcggcg
    13861 agcttgatca gaatgcgtga tttatcaaca tcctgctgct ggtagagatc caccagatgg
    13921 cgtgctttct cgatactttt ttctttatcg aacgataacc gcacgtcgac ttcagtggag
    13981 acgcgaccgg gaatactttt cagtatttcc gcgccaaaat taaccgccag tttatcgctg
    14041 gctgccgcaa cctgctgttc ctgcgtaccg ccgtgttttt ttccccaggc aatcgcatcc
    14101 tcaatcaaat gaccatactg ctcaagcccg gcggctttta acagtaaaga gggatttgtc
    14161 gtggcatcct gcggctggta gtggcggatg gactcgatgt cgccgctgtc ggcgacgacg
    14221 gtagtgaatt gtttgatgcc gtctagctgg ttcataggaa atactccttg aaaagtaaag
    14281 tgttagatga gtgtgttgat tcacacttct gaaagattga tacactacat aaccaaaaag
    14341 catagcagac aggcatggta ttgctggtat aagcaggtaa catggctgtt ataagttgat
    14401 aacaaactct tgcgccgcgt cgtgatagtt tgcagacctt caaagtttgt gttgcgcagt
    14461 acggtgataa tgtgcggcgc accaggccgc gtcacttttt gaacgatacg tgaaaggaac
    14521 aacaaaatgg atgagcagtt aaaacaaagc gcccttgatt tccacgaatt tccggtaccc
    14581 ggtaaaattc aggtttctcc gactaagccc cttgccaccc aacgcgatct ggcgttggct
    14641 tactcgccag gcgtggcggc gccctgcctg gaaatcgaaa aagatccgct ggcagcctac
    14701 aaatacaccg cgcgcggcaa ccttgtcgcg gtcatttcca acggtacagc ggtgctgggg
    14761 ttaggcaaca tcggcgcgct ggccggcaag ccggtcatgg aaggcaaagg cgttctgttt
    14821 aaaaaattcg ccggcatcga tgtgtttgac attgaagtcg atgagcttga tccggacaaa
    14881 tttatcaatg tggtcgcagc gctggagccg acctttggcg gcattaacct cgaagacatt
    14941 aaagcgccgg aatgtttcta tattgagcag aaactgcgcg agcgcatgaa catcccggtt
    15001 ttccatgacg atcagcacgg aacggcgatc atcagtacgg ccgccattct taatggcctg
    15061 cgagtcgtag agaaaaatat ttccgacgtg cggatggtcg tctccggcgc aggggcggcg
    15121 gcaatcgctt gtatgaacct gctggtcgcg ttggggatgc agaagcacaa catcgtggtg
    15181 tgcgactcta agggcgttat ttacaaaggc cgtgagccga atatggcgga gaccaaagcg
    15241 gcctatgcgg tagacgacag cggcaagcgc acgctggatg aggtcattga cggcgcggat
    15301 attttcctcg gctgttcagg cccgaaagtg ctgactcagg agatggtgaa gaaaatggcc
    15361 cgcgcgccaa tgattctggc gctggctaac ccggaaccgg aaattctgcc gccgctggcg
    15421 aaagaagtgc gtccggacgc catcatctgt accggtcgtt ccgactatcc gaaccaggtg
    15481 aacaacgtat tgtgcttccc gtttatcttc cgcggcgcac tggacgtcgg cgcgacggcg
    15541 atcaacgaag agatgaaact ggcggcggtc cgtgcgattg ccgagctggc gcacgccgaa
    15601 cagagcgaag tggtggcctc ggcctatggc gatcaggacc tgagctttgg gccggaatac
    15661 attattccga aaccgtttga cccgcgtctg attgtcaaaa tcgctccggc ggtcgcgaaa
    15721 gcggcaatgg attccggcgt ggcgacgcgc ccgattgctg actttgatgc ctatatcgat
    15781 aaactgaccg agtttgtcta caaaactaac ctgttcatga agccgatctt ctcgcaggca
    15841 cgcaaagatc cgaagcgcgt agtgctgccg gaaggggaag aggcgcgcgt gctgcacgca
    15901 acccaggagt tgataaccct ggggctggcg aagcccatcc tgatcgggcg tccgagcgtg
    15961 atcgaaatgc gtatccagaa actggggtta cagatcaaag cgggcgttga tttcgagatc
    16021 gtgaataatg aatccgatcc gcgcttcaaa gagtactgga gcgagtatta ccagatcatg
    16081 aagcgtcgcg gggtaactca ggaacaggcg cagcgtgcga tgatcggcaa ccatacggcc
    16141 attggcgcga tcatggtgca gcgtggagaa gcggatgcga tgatctgcgg caccatcggc
    16201 gactaccatg agcatttcag cgtcgtgaaa gccgtctttg gctaccgtga cggcgtgcat
    16261 acggcagggg cgatgaacgc cttactgctg ccaagcggca acacttttat cgccgatact
    16321 tatgttaacg aagatcccac gccggaacag ttggcggaga tcgccgtaat ggcggcggaa
    16381 accgttcgcc gctttggtat tgagccgaaa gtcgcgctgt tgtcgcactc taactttggt
    16441 tcctcaaatt cgctgtccgc cagcaaaatg cgcgaaaccc ttgagcgggt acgcgaacga
    16501 gcgcccgatc tgatgattga cggtgagatg cacggtgatg cggcgttggt ggaaagtatt
    16561 cgtaatgacc ggatgccgga tagtccgctg aagggagccg ccaatattct ggtgatgccg
    16621 aatatggaag ccgcccgcat tagttacaac ttactccgcg tctccagttc cgaaggcgtc
    16681 acggtcggcc cggtcctgat gggcgtgtct aaaccggtac atgtattaac gccgatcgcc
    16741 tctgtacgcc gtatcgtgaa tatggtggcg ttagcggtag ttgaagcgca aaccacgccg
    16801 ctttaataac gcattactct ctcttctggc gcaggttctc ctgcg
//
LOCUS       DAJVBX010000093        16843 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.093, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000093 DAJVBX010000000
VERSION     DAJVBX010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 16843)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16843)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16843
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.093"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            4..1218
                     /locus_tag="OPV72_002555"
     CDS             4..1218
                     /locus_tag="OPV72_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462448.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HCR9914818.1"
                     /translation="MKFERHHRILKELSISGVVKVSNLAKSLKVTKETIRSDLNELAG
                     QGYLTRCHGGAFITLDSLDNVAKNEIAYVLEKYESAQKIKKGLSAMKNNVCVIGSFNV
                     DIISYLPRLPSTGESLLADKFIFSPGGKGCNQALAASYADSDVHFITKVGSDHFSDYA
                     INFINSSKIHKSVIYQTKETQTGTATIMVNGDTGDNVIAIYPGANMTISPDEITIQKE
                     AIVHSDIVLVQLETNYEALQQTIRLAQKNDIPVIINPAPYNDMVNTIIDNIDYITPNE
                     TEAGLLANMAVNDIESAKCAAKIIHQKGVKNTIITLGSKGSLAYDGTQFIYSPAFPAV
                     VKNTAGAGDAFNGALSSGLAKGKSLASALCYASAFASLAVETPNASDMPENDSVLHRI
                     QGSHYKQTISTH"
     gene            1234..1995
                     /locus_tag="OPV72_002556"
     CDS             1234..1995
                     /locus_tag="OPV72_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HCR9914819.1"
                     /translation="MNNTQKKLKVLFIGESWHIHMIHSKGYDSFTSSKYEEGATWLLE
                     CLRKGGVDIDYMPAHTVQIAFPESIDELNRYDVIVISDIGSNTFLLQNETFYQLKIKP
                     NALESIKEYVKNGGGLLMIGGYLSFMGIEAKANYKNTVLAEVLPVIMLDGDDRVEKPE
                     GICAEAVSPEHPVVNGFSDYPVFLGYNQVVARDDADVVLTINNDPLLVFGEYQQGKTA
                     CFMSDCSPHWGTQQFMSWPFYTDLWVNTLQFIARK"
     gene            2049..3020
                     /locus_tag="OPV72_002557"
     CDS             2049..3020
                     /locus_tag="OPV72_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HCR9914820.1"
                     /translation="MNKNKYSTPLLMLATILAGMLSPMQSAVNGQLGHWLQDGNACAV
                     ISFASGLVVMFFIIIARKETRQQFASIPTLIKKRKIPLWNWFAGLCGAMVVFSEGASA
                     SALGVATFQTALISALLLSGLLCDRFGIGVEEKKYFTPWRITGALFAVIATIFVVSPQ
                     WHSTSFILLAILPFLAGLLAGWQPAGNAKVAEATGSMLVSITWNFIVGFCVLGAALAI
                     RIALGHVTIQLPDTWWMYLGGPLGLLSIGLMAILVRGLGLLMLGVASTAGQLLGSVLI
                     DELIPSLGNTVYLVTIIGTLFALVGAIVTTIPEYRASKMAQKMEVSE"
     gene            3017..4051
                     /locus_tag="OPV72_002558"
     CDS             3017..4051
                     /locus_tag="OPV72_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotriesterase"
                     /protein_id="HCR9914821.1"
                     /translation="MKGFLQTVTGPVAHTDMGLTLPHEHLFNDLSSVVDEPHYAFSQQ
                     LVGKKVSADLQWGLKHDPYCCADNMDRKEIDDVIFEINNFMSLGGRTIVDATGSESIG
                     RDASALREVALKTGLNIVASSGPYLEKFESTRIHKPVELLASLIDKELNQGIGETDIR
                     AGMIGEIGVSPAFTQAERNSLRAASLAQCNNPHTAMNIHMPGWLRLGDEVLDIVLEEM
                     NVSPAKVSLAHSDPSGKDVVYQRKMLDRGVWLEFDMIGLDITFPKEGVAPGVQETADA
                     VANLIALGYADQIVLSHDVFLKQMWAKNGGNGWGFVPNVFLAYLAARGVDNDTLRKLC
                     IDNPARLLTA"
     gene            complement(4096..5838)
                     /gene="ggt"
                     /locus_tag="OPV72_002559"
     CDS             complement(4096..5838)
                     /gene="ggt"
                     /locus_tag="OPV72_002559"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="HCR9914822.1"
                     /translation="MKPTFMRWVAIAALLAGGTFSAVANPPVAPPVSYGVEEDVFHPV
                     RATQGMVASVDAMATQVGVDILKQGGNAVDAAVAVGYALAVTHPQAGNLGGGGFMLLR
                     TKDGATTAIDFREMAPAAATRDMFLDDQGNADAKKSLTSHLASGTPGTVAGFSLALEK
                     YGTMPLNKVVRPAMKLAEEGFVVNDALADDLKTYGSEVIPNHENSKAIFWKDGEPLKK
                     GDKLIQKNLAKSLEMIAENGPAAFYKGAIADQIAGEMQKNGGLMTKEDLASYKAVERT
                     PISGDYRGYQVFSMPPPSSGGIHIVQILNILENFDMKKYGFGSADAMQIMAEAEKYAY
                     ADRSEYLGDPDFVKVPWQALTNKAYAKTLADQIDINKAKPSSQIKPGKLAPYESNQTT
                     HFSVVDKDGNAVAVTYTLNTTFGTGIVAGNTGILLNNQMDDFSAKPGVPNVYGLVGGD
                     ANAVEPKKRPLSSMSPTIVVKDGKTWLVTGSPGGSRIITTVLQMVVNSIDFGMNVAEA
                     TNAPRFHHQWLPDELRVEKGFSPDTLKLLEQKGQKVALKEAMGSTQSIMVGPDGELYG
                     ASDPRSVDDLTAGY"
     gene            5964..6335
                     /locus_tag="OPV72_002560"
     CDS             5964..6335
                     /locus_tag="OPV72_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2756 family protein"
                     /protein_id="HCR9914823.1"
                     /translation="MKRLLLITALLPFAVLAQPINTMNNPNQPGYQIPSQQRMQTQMQ
                     TQARSQQQNLQSQLNANTQRVQQGQPGNGMLGQQTLPNTQGGMLSGSGNPDRMLNHSQ
                     PMLQQDSGTPQPDIPLKTISP"
     gene            complement(6332..7072)
                     /gene="ugpQ"
                     /locus_tag="OPV72_002561"
     CDS             complement(6332..7072)
                     /gene="ugpQ"
                     /locus_tag="OPV72_002561"
                     /EC_number="3.1.4.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HCR9914824.1"
                     /translation="MSNWPYPHIVAHRGGGKLAPENTLAAIDVGARYGHTMIEFDAKL
                     SKDGEIFLLHDDNLERTSNGWGVAGELNWQDLLRVDAGGWFSGEFKGEPLPLLSQVAE
                     RCRKHGMMANIEIKPTTGSGRLTGRVVALAARELWAGMTPPLLSSFEIEALEAAQAAV
                     PELPRGLLLDKWREDWRELTTRLGCVSLHLNHKLLDETRVQEIKAAGLRILVYTVNQP
                     QRAAELLRWGVDCICTDRIDDIGPHFQF"
     gene            complement(7069..8139)
                     /locus_tag="OPV72_002562"
     CDS             complement(7069..8139)
                     /locus_tag="OPV72_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate import ATP-binding
                     protein UgpC"
                     /protein_id="HCR9914825.1"
                     /translation="MAGLKLQAVTKSWGGKTQVIQPLTLDVADGEFIVMVGPSGCGKS
                     TLLRMVAGLERVTSGDIWIDRKRVTEMEPKDRGIAMVFQNYALYPHMSVEENMAWGLK
                     IRGMSKAHIEERVREAARILELDGLLKRRPRELSGGQRQRVAMGRAIVREPAVFLFDE
                     PLSNLDAKLRVQMRLELQHLHRRLRTTSLYVTHDQVEAMTLAQRVMVMNKGVAEQIGT
                     PVEVYEKPASRFVASFIGSPAMNLLDGVISASGDRFELPGGLALPIGAGYRGHAGRKM
                     TLGIRPEHIALSSQAEGGVPLTVDTLEILGADNLAHGRWGDQKLVVRLAHQQRPAAGS
                     TLWLRLPEHQRHLFDGETGQRV"
     gene            complement(8142..8987)
                     /gene="ugpE"
                     /locus_tag="OPV72_002563"
     CDS             complement(8142..8987)
                     /gene="ugpE"
                     /locus_tag="OPV72_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter permease
                     UgpE"
                     /protein_id="HCR9914826.1"
                     /translation="MIENRRGLTIFSHTMLILGIAVILFPLYVAFVAATLDDRAVFET
                     PMTLLPGTQLLENIKTIWVNGVGVNSAPFWLMMLNSFIMAFSITVGKITVSMLSAFAI
                     VWFRFPLRNLFFWMIFITLMLPVEVRIFPTVEVIANLKMLNSYAGLTLPLMASATATF
                     LFRQFFMTLPDELVEAARIDGASPMRFFRDIVLPLSKTNLAALFVITFIYGWNQYLWP
                     LLIITDVNLGTAVAGIKGMIATGEGTTQWNQVMAAMLLTLIPPVVIVLAMQRAFVRGL
                     VDSEK"
     gene            complement(8984..9871)
                     /gene="ugpA"
                     /locus_tag="OPV72_002564"
     CDS             complement(8984..9871)
                     /gene="ugpA"
                     /locus_tag="OPV72_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter permease
                     UgpA"
                     /protein_id="HCR9914827.1"
                     /translation="MSSSRPVFRSRWLPYLLVAPQLVITVIFFIWPAGEALWYSLQSV
                     DPFGFSSQFVGLENFVALFHDSYYLDAFWTTIKFSALVTFSGLLVSLFFAALVDYVVR
                     GSRFYQTLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLGEFGYDWNHAQNSGQAMFL
                     VVFASVWKQISYNFLFFFAALQSIPRSLVEAAAIDGAGPIRRFFRLSLPLIAPVSFFL
                     LVVNLVYAFFDTFPVIDAATAGGPVQATTTLIYKIYCEGFTGLDLSASAAQSVVLMFL
                     VIILTVVQFRYVESKVRYQ"
     gene            complement(9976..11292)
                     /gene="ugpB"
                     /locus_tag="OPV72_002565"
     CDS             complement(9976..11292)
                     /gene="ugpB"
                     /locus_tag="OPV72_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     substrate-binding protein UgpB"
                     /protein_id="HCR9914828.1"
                     /translation="MISLRHTALGLALSLAFTGQALAVTTIPFWHSMEGELGKEVDSL
                     AQRFNQANPDYKIVPVYKGNYEQNLSAGIAAFRTGNAPAILQVYEVGTATMMASKAIK
                     PVYEVFKDAGINFDESQFVPTVAGYYTDAKSGHLLSQPFNSSTPVLYYNKDAFKKAGL
                     DPEQPPKTWQELADYTAKLRAAGMKCGYASGWQGWIQLENFSAWNGLPFASKNNGFDG
                     TDAVLEFNKPEQVKHIALLEEMNKKGDFSYVGRKDESTEKFYNGDCAMTTASSGSLAN
                     IRQYAKFNYGVGMMPYDADIKGAPQNAIIGGASLWVMQGKDKETYTGVAKFLDFLAKP
                     ENAAEWHQKTGYLPITTAAYELTREQGYYDKNPGADIATRQMLNKPPLPFTKGLRLGN
                     MPQIRTIVDEELESVWTGKKTPQQALDTAVDRGNQLLRRFEKASKS"
     gene            complement(11524..11802)
                     /locus_tag="OPV72_002566"
     CDS             complement(11524..11802)
                     /locus_tag="OPV72_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000621258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914829.1"
                     /translation="MIRSGACIMGTLLFAASFSVNALTSNDFDPRDPAIWQEETATPY
                     PLAATTCEVRHHPDCATWEDEKSDIQRERERRDQRRLQNLYKKYSHRD"
     gene            complement(11966..12679)
                     /gene="livF"
                     /locus_tag="OPV72_002567"
     CDS             complement(11966..12679)
                     /gene="livF"
                     /locus_tag="OPV72_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter ATP-binding protein LivF"
                     /protein_id="HCR9914830.1"
                     /translation="MEKTMLTFEKVSAHYGKIQALHDVSLHINQGEIVTLIGANGAGK
                     TTLLGTLCGDPRASSGRVVFDGKDITDWQTAKIMREAVAIVPEGRRVFSRMTVEENLA
                     MGGFFAERDRFQERIKWVYELFPRLHERRIQRAGTMSGGEQQMLAIGRALMSQPRLLL
                     LDEPSLGLAPIIIQQIFDTIEQLREQGMTIFLVEQNANQALKLADRGYVLENGHVVLS
                     DTGDALLANEAVRSAYLGG"
     gene            complement(12681..13448)
                     /gene="livG"
                     /locus_tag="OPV72_002568"
     CDS             complement(12681..13448)
                     /gene="livG"
                     /locus_tag="OPV72_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter ATP-binding protein LivG"
                     /protein_id="HCR9914831.1"
                     /translation="MSQPLLAVNGLMMRFGGLLAVNNVSLELREREIVSLIGPNGAGK
                     TTVFNCLTGFYKPTGGTITLRERHLEGLPGQQIARMGVVRTFQHVRLFREMTVIENLL
                     VAQHQQLKTGLFSGLLKTPAFRRAQSEALDRAATWLERIGLLEHANRQASNLAYGDQR
                     RLEIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNHHNTTILLIEHDMKLVM
                     GISDRIYVVNQGTPLANGTPEEIRNNPDVIRAYLGEA"
     gene            complement(13445..14722)
                     /gene="livM"
                     /locus_tag="OPV72_002569"
     CDS             complement(13445..14722)
                     /gene="livM"
                     /locus_tag="OPV72_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched chain amino acid ABC transporter
                     permease LivM"
                     /protein_id="HCR9914832.1"
                     /translation="MKPMHIAMALFSAAMFFVLAGVFMGVQLELDGTKLVVDTAADIR
                     WQWIFIGTAVVFFFQLLRPMFQKAVKHVSGPKFILPAIDGSTVKQKLFLMALLVIAVA
                     WPFMVSRGSVDIATMTMIYIILGLGLNVVVGLSGLLVLGYGGFYAIGAYTFALLNHYY
                     GLGFWTCLPLAGLVSAAAGFLLGFPVLRLRGDYLAIVTLGFGEIVRILLLNNTEITGG
                     PNGISQIPKPTLFGLEFSRNTREGGWDTFSNFFGVKYDPSDRVIFLYLVALLLVVLSL
                     FVINRLLRMPLGRAWEALREDEIACRSLGLSPTRIKLTAFTISAAFAGFAGTLFAARQ
                     GFVSPESFTFAESAFVLAIVVLGGMGSQFAVILAAVLLVVSRELMRDFNEYSMLMLGG
                     LMVLMMIWRPQGLLPMTRPQLKLKSGQAKGEQA"
     gene            complement(14719..15645)
                     /gene="livH"
                     /locus_tag="OPV72_002570"
     CDS             complement(14719..15645)
                     /gene="livH"
                     /locus_tag="OPV72_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010436488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter permease LivH"
                     /protein_id="HCR9914833.1"
                     /translation="MSEQFLYFLQQMFNGVTLGSTYALIAIGYTMVYGIIGMINFAHG
                     EVYMIGSYVSFMIIAALMMMGIDTSWLLVAAGFIGAIIIASAYGWSIERVAYRPVRNS
                     KRLIALISAIGMSIFLQNYVSLTEGSRDVALPSLFNGQWIVGSSENFSASITTMQAVI
                     WIVTFLAMLALTIFIRYSRMGRACRACAEDLKMASLLGINTDRVIALTFVIGAAMAAV
                     AGVLLGQFYGVINPYIGFMAGMKAFTAAVLGGIGSIPGAMIGGLILGVAEALSSAYLS
                     TEYKDVVSFALLILVLLVMPTGILGRPEVEKV"
     gene            complement(15705..16814)
                     /gene="livK"
                     /locus_tag="OPV72_002571"
     CDS             complement(15705..16814)
                     /gene="livK"
                     /locus_tag="OPV72_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter substrate-binding protein LivK"
                     /protein_id="HCR9914834.1"
                     /translation="MKRKAKTIIAGIVALAVSQGAMADDIKVAIVGAMSGPVAQWGDM
                     EFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVAVANKIVNDGIQYVIGHLCS
                     SSTQPASDIYEDEGILMISPGATNPELTQRGYQYIMRTAGLDSSQGPTAAKYILETVK
                     PQRIAIIHDKQQYGEGLARSVQDGLKQGNANIVFFDGITAGEKDFSALIARLQKENID
                     FVYYGGYYPEMGQMLRQARANGLKTQFMGPEGVGNASLSNIAGGAAEGMLVTMPKRYD
                     QDPANKAIVEALKADKKDPSGPYVWITYAAVQSLATAMTRSASHAPLDLVKDLKANGA
                     DTVIGPLKWDEKGDLKGFEFGVFQWHADGSSTVAK"
BASE COUNT         4066 a         4723 c         4252 g         3802 t
ORIGIN      
        1 aaaatgaaat ttgaacgcca tcatagaata ttgaaggaac tcagtatttc gggagttgta
       61 aaagtttcaa atctggcgaa aagtctcaag gtaacaaagg aaactattcg ttcagatctc
      121 aatgaacttg ccggacaggg atatcttact cgctgtcatg gtggtgcatt tattaccctt
      181 gattctcttg ataacgtcgc aaaaaatgaa attgcttatg tgctggaaaa atatgaatca
      241 gcgcagaaaa taaaaaaagg tctctctgcc atgaaaaata atgtatgtgt tattggctcg
      301 ttcaatgttg atattatcag ttatctaccg agattaccct caacgggaga atcattgctg
      361 gccgataaat ttattttttc acccggcggt aagggatgta atcaggcatt agcagcaagc
      421 tatgccgatt ctgatgtgca ttttattact aaagtcggct cagatcattt tagcgattac
      481 gccattaatt ttataaactc atcaaaaatc cataaaagtg ttatctacca gaccaaagaa
      541 acacaaacag gtacagcaac catcatggtg aatggtgata ccggagataa tgtcatcgct
      601 atctaccctg gcgccaacat gacaatttcc cctgatgaaa tcaccattca aaaagaagcc
      661 attgttcatt cagatattgt tcttgtccaa ctggagacga attacgaagc gctgcagcaa
      721 acaattcgtc tcgcacaaaa aaatgacata ccggtcatca tcaatccagc gccgtacaat
      781 gacatggtta acaccatcat tgataacatt gactatatta cgccaaatga aacggaagcc
      841 ggcctgctgg ccaatatggc ggttaatgat atcgaatcag ccaaatgcgc ggccaaaatt
      901 attcaccaga aaggcgtcaa aaataccatt attacattag gtagcaaagg ttcgcttgct
      961 tatgacggca cacaattcat ctattccccg gcatttccgg cagttgtaaa aaatacggcg
     1021 ggagcgggtg acgctttcaa tggcgccctc tcatctggcc ttgcaaaagg aaagtcactg
     1081 gcatccgcat tgtgctacgc cagcgcattt gcctcacttg cggttgaaac gcctaatgcc
     1141 tctgatatgc cggaaaacga ctccgttctt catcgtattc agggttcaca ttacaaacaa
     1201 actatctcta ctcactaaat caaggagcag actatgaaca atacgcagaa aaaactaaag
     1261 gtgctcttta ttggagaatc ctggcatatt catatgattc attcaaaagg ttatgacagt
     1321 ttcacctcca gtaaatatga agaaggcgcg acatggttac tggaatgcct gaggaaaggc
     1381 ggcgttgata ttgattacat gcctgcccac acggtacaaa ttgcctttcc agagagtatt
     1441 gacgaattaa atcgttatga tgtgattgtt attagcgaca ttggtagtaa taccttcctg
     1501 ctacaaaatg aaaccttcta tcagctaaaa ataaaaccaa acgctctgga atccattaaa
     1561 gagtacgtca aaaatggcgg tggactactc atgattggcg gttatctgtc atttatgggt
     1621 attgaggcaa aagccaatta taagaacacc gttcttgctg aggttctgcc agttattatg
     1681 cttgacggcg atgaccgggt agaaaagcca gagggtattt gtgctgaggc tgtctcacct
     1741 gaacatcctg ttgttaacgg gttctcagat tacccggtat ttcttggata taaccaggtc
     1801 gtcgccagag acgatgccga tgtcgtatta acaataaata atgacccatt gttagtgttc
     1861 ggtgaatacc aacagggtaa aaccgcctgc tttatgagtg actgctcccc acactgggga
     1921 acccagcagt ttatgtcatg gccattttat accgacctgt gggtcaacac gcttcaattc
     1981 atcgccagaa aataaaaaac aatggagtaa cgaaagttac tccttttata aaatataagg
     2041 attgatgtat gaacaagaat aagtactcaa cccccttact gatgcttgcc accatcttag
     2101 ccggtatgct ttccccgatg cagtctgccg ttaatgggca gttaggacat tggttacaag
     2161 acggtaatgc ttgcgcagta atctcgtttg ccagcggtct ggtcgtcatg ttttttatta
     2221 ttattgcgcg caaagaaaca cgccagcaat tcgcctcaat ccctactctg attaaaaaga
     2281 gaaaaatccc gctatggaat tggtttgcag gattatgcgg ggcgatggtc gtattttctg
     2341 aaggcgcatc cgccagcgcg ctgggcgttg ccacctttca aacggcatta atttccgctc
     2401 tgcttctttc cggcctgctg tgcgaccgtt ttggcatcgg cgtggaggag aaaaaatatt
     2461 ttacgccatg gcgcattact ggcgcattgt tcgccgttat cgccaccatt tttgtcgtgt
     2521 cgccacagtg gcactcaacc tcgtttatcc tgctcgctat cctccccttt ttggcagggt
     2581 tactcgctgg ctggcagcct gcggggaatg cgaaagtcgc cgaggcaacg ggctccatgc
     2641 tggtgtccat tacatggaac ttcatcgtcg gcttttgtgt cctgggcgcg gcgctggcga
     2701 tacgtatcgc attaggccat gtcaccatcc agttacccga tacatggtgg atgtatctcg
     2761 gtggtccgct gggtctgcta tccatcgggc taatggcgat tctggtgaga ggcttagggc
     2821 tattgatgct gggcgtagcg tcaacagcag gccaactgct tggctcagtg ctaattgatg
     2881 aattgatccc ttcattaggc aatacggtct acctggtcac catcatcggt acgctgttcg
     2941 cgttagtcgg tgcgattgtg accaccatcc ctgaatacag agcatccaaa atggcgcaaa
     3001 aaatggaggt gtcagaatga aaggtttcct gcaaaccgta acaggcccgg tggcgcatac
     3061 ggatatgggg ctgacgctac cgcatgaaca tctgtttaac gatctgtctt cggtcgtaga
     3121 cgagccacat tatgcttttt cacagcaact ggtgggaaag aaagtcagtg ctgacctgca
     3181 gtgggggctg aaacacgacc catactgctg cgccgataac atggacagaa aagagattga
     3241 tgatgttatc ttcgaaatca ataactttat gtctttgggc ggcaggacga ttgtcgacgc
     3301 caccggttca gaatccattg gacgggatgc ctcagcgcta cgagaagttg ccttaaaaac
     3361 gggtttgaat atcgttgcgt catccgggcc ttatctggag aaatttgaaa gcacccggat
     3421 ccataaacct gttgagctgt tagcctcact cattgataaa gaactgaatc agggtattgg
     3481 cgagacggat attcgcgctg gcatgatcgg tgaaatcggc gtatctcccg cgtttaccca
     3541 agcggagcgt aacagcctgc gggcagcgtc tctggcacaa tgtaacaacc cccacacggc
     3601 gatgaatatc catatgccag ggtggctgcg actgggtgat gaggtgctgg atatcgtgct
     3661 ggaagaaatg aacgtctctc cggcaaaagt ctcgctggcg cattcggacc cttcaggaaa
     3721 agatgtcgtc tatcaacgta aaatgctcga ccgcggcgta tggcttgaat ttgacatgat
     3781 tggtctggac atcacctttc caaaagaagg tgtcgcgccg ggcgttcagg agaccgcaga
     3841 tgcagtagcg aatctgattg cactgggtta cgccgaccaa atcgttttaa gccatgatgt
     3901 ttttctcaaa cagatgtggg cgaaaaatgg cggaaatggc tgggggtttg tcccgaatgt
     3961 tttcctcgcc tatttggctg ctcgcggagt agacaacgat actctgcgca agctttgtat
     4021 tgataatcca gcccgattac tcacggcata atctgcaaat agcccggtgt ctgacaccgg
     4081 gcctggaatt aaaaatcagt atcccgccgt taaatcatcc acggaacgcg ggtcagacgc
     4141 accgtacagt tcgccatccg gtccaaccat aatactttgg gtgctgccca tcgcttcttt
     4201 cagcgcgact ttctgccctt tctgttccag caacttcagc gtatcggggc tgaagccctt
     4261 ttctacccgc agttcgtccg gcaaccattg atgatggaaa cgcggcgcgt tggtcgcttc
     4321 ggcgacgttc atgccaaaat caatgctgtt cactaccatt tgcagcacag tagtgatgat
     4381 tcgactcccg ccagggctac cggtcaccag ccaggttttg ccgtctttta ccacgatagt
     4441 cggcgacatc gacgacagcg gacgtttttt tggttcgacc gcgttagcat cgccgcccac
     4501 taggccataa acattgggta caccaggctt agcagaaaaa tcatccattt gattattcag
     4561 cagaataccg gtatttcccg ccacaattcc tgtgccgaag gtggtgttca gggtataggt
     4621 caccgccaca gcattgccgt ctttatccac caccgagaag tgggtggtct ggttgctttc
     4681 atacggggcg agcttgcccg gtttgatctg gctggaaggt tttgccttat taatatctat
     4741 ttgatcggcc aacgttttcg cataggcttt gttggtcagc gcctgccacg gcactttcac
     4801 aaagtccgga tcgcccagat actctgagcg gtcagcgtag gcgtattttt ccgcttccgc
     4861 catgatttgc atggcatcgg cgctgccaaa gccgtacttc ttcatgtcga aattttcaag
     4921 aatattgagg atttgcacga tgtgaatacc gcccgaggac ggcggcggca tggagaaaac
     4981 ctgatacccg cgatagtcac cgctgattgg cgtacgctca acggctttat agctggctaa
     5041 atcctctttg gtcatcagac cgccgttctt ctgcatttcc ccggcaatct ggtcggcaat
     5101 cgccccttta taaaacgcag ccgggccgtt ttcggcaatc atttccaggc ttttcgccag
     5161 attcttctgg atcagcttat cgcctttttt cagcggctcg ccgtctttcc agaaaatggc
     5221 tttgctgttc tcatggttgg ggatcacttc gctgccgtaa gtttttaagt cgtcggccag
     5281 cgcatcgtta accacaaaac cctcttccgc cagcttcatc gccggacgca ccactttatt
     5341 cagcggcatc gtgccgtatt tctccagcgc cagcgagaaa cccgccacgg tacccggcgt
     5401 accggatgcc agatgcgacg tcagcgactt tttcgcatcg gcgttaccct gatcgtcgag
     5461 gaacatatca cgggtcgcgg cagccggcgc catttcacga aaatcgatcg ccgtggtagc
     5521 gccatcttta gtgcgcagca gcataaatcc cccgccgccc agattcccgg cttgcggatg
     5581 cgtgacagcc agcgcatagc ccacggcgac ggcggcatcc acggcattac cgccctgctt
     5641 taagatatcc acgccaacct gcgtcgccat tgcatccacg gacgccacca tcccttgcgt
     5701 cgcccgtaca ggatgaaaga catcttcttc aacaccatag gagactggcg gcgcgacggg
     5761 aggattggcc accgcgctaa acgtcccccc ggccagcaga gcggcgatcg ccacccagcg
     5821 cataaacgtt ggtttcatcg ttgtttttct ccagataaag gggtgtatgt cccgtttaat
     5881 cctggtccac aacgcttaaa aaatcatcat catggcgaaa tagaggtaca cttaaaaaga
     5941 ggcctcatcg ggaggagacg acaatgaaac gcttactact tattacggct ttattaccct
     6001 ttgctgtatt ggcccagcca attaacacta tgaataatcc taatcagcca ggttatcaaa
     6061 tccccagcca gcagcgtatg cagacgcaga tgcaaacgca ggcgcgcagc cagcagcaaa
     6121 atctacagtc gcagttgaat gccaatacgc agcgggttca gcagggacag ccgggcaacg
     6181 gtatgctcgg tcagcaaacg ctgcccaata cgcagggcgg aatgctcagc ggcagcggaa
     6241 atccggaccg gatgctaaac cattcccagc caatgttgca gcaggacagc gggacgccgc
     6301 agcctgacat cccgctgaaa actatcagcc cttaaaactg aaagtgaggg ccgatgtcat
     6361 caatgcgatc ggtgcagata caatccacgc cccagcgcag cagctctgcc gcccgctggg
     6421 gctgattgac ggtatacacc agaatccgca gacccgcggc cttaatctct tgcactcgcg
     6481 tctcatcgag taatttatgg ttgagatgga gggaaacaca gcccagacgg gtcgtcagtt
     6541 cacgccagtc ttcacgccat ttatccagta gtaacccgcg cggcagttca ggtactgccg
     6601 cctgcgccgc ttccagcgcc tctatctcaa aggaagaaag cagcggcggc gtcatcccgg
     6661 cccacagttc gcgggcggcc aacgccacga cacgtcctgt tagccttccg ctccccgttg
     6721 tcggtttgat ctcaatattc gccatcatgc cgtgtttacg gcagcgctcc gccacctgcg
     6781 agagcaacgg cagcggctcg cctttaaatt cgccgctaaa ccaaccgcca gcgtccacac
     6841 gcaataaatc ctgccagttc aactcgcccg ccacacccca accattgctg gtgcgctcca
     6901 ggttatcgtc atgcagcagg aaaatttcgc cgtctttcga cagcttggca tcaaactcaa
     6961 tcatggtgtg cccgtatcgc gcgcccacgt caatcgccgc cagagtgttt tccggcgcca
     7021 gtttaccgcc gccgcgatgg gcgacaatgt gaggataagg ccagttactc atacacgttg
     7081 tcctgtttcg ccatcaaaaa gatgtcgctg atgttccggc agacgcagcc atagcgtact
     7141 gcccgccgcc gggcgctgct gatgcgccaa ccgcaccacc agtttctgat cgccccagcg
     7201 cccatgcgcc agattatccg cgcccagaat ctccagcgtg tctaccgtta acggcacgcc
     7261 gccttccgcc tgcgagctta acgcaatatg ctccgggcgg atacccagcg tcattttacg
     7321 tccagcatga ccccgatagc ccgcaccaat cggcaacgcc agaccgccag gcaattcgaa
     7381 acggtcgccg gaagcgctga taacgccgtc caacagattc atcgccgggc tgccaataaa
     7441 gctcgccacg aagcgactgg ccggtttttc atacacctct accggcgtgc caatctgttc
     7501 tgcgacgcct ttattcatca ccatcacccg ctgggccagc gtcatcgcct ctacctgatc
     7561 gtgagtaaca tagagcgagg tggtacgaag gcgacgatgc agatgttgta actccagacg
     7621 catctgcacg cgcagcttgg cgtcgaggtt agagagcggt tcgtcgaata aaaagactgc
     7681 cggctcgcgg acgatcgcgc gccccattgc cacgcgctgc cgttgaccgc cggaaagctc
     7741 gcgtggacgg cgtttaagca ggccgtccag ctccagaatg cgcgccgcct cccgcacgcg
     7801 ttcttcaata tgcgctttgc tcataccgcg aattttcagc ccccacgcca tgttctcctc
     7861 tacgctcata tggggataga gagcatagtt ctgaaatacc atcgcgatgc cgcgatcttt
     7921 gggctccatc tcggtgaccc gtttgcgatc aatccagata tcgccgctgg tcacgcgttc
     7981 cagaccggcc accatccgca acaacgttga tttgccgcag ccggacggcc cgaccatcac
     8041 gataaattcg ccatccgcca cgtccagcgt cagcggttga atgacctggg ttttgccgcc
     8101 ccagcttttg gttactgcct gtagttttaa accagccatt tttatttctc actgtccact
     8161 aaaccacgca caaacgcccg ttgcatggct aacacaatta cgaccggggg aatcagagtc
     8221 agcagcattg ccgccatcac ctggttccat tgcgtggtac cttcgccagt ggcgatcatc
     8281 cctttgatac ccgctacggc agtgccaaga ttcacgtcgg tgataatcaa cagcggccac
     8341 agatactggt tccagccgta gataaaggtg atgacgaata acgccgccag gttggttttt
     8401 gacagcggca acacgatgtc gcggaaaaag cgcatcggcg acgcgccgtc aatacgggcc
     8461 gcctccacca gttcatccgg aagcgtcatg aagaattgac gaaacaggaa agtggcggta
     8521 gcggacgcca tcagcggtaa cgtcagaccg gcatagctgt tgagcatttt caggttggcg
     8581 atcacttcca ccgtcgggaa gatacgcact tcaaccggca acatcagggt gataaaaatc
     8641 atccagaaga acaggttacg caggggaaaa cgaaaccaga cgatggcgaa tgcggaaagc
     8701 atagataccg tgattttgcc taccgtaatg ctgaacgcca taatgaaact gttaagcatc
     8761 atcagccaga atggcgcgct attaacaccg acgccgttga cccaaatagt tttgatattc
     8821 tccagtaact gcgtgccggg aagcagcgtc atcggcgtct caaacaccgc gcggtcgtcc
     8881 agcgtcgccg cgacaaacgc gacatacagc ggaaacaaaa tgaccgcgat ccccagaatc
     8941 agcatggtat ggctgaatat tgtcagcccg cgacgattct ctatcattgg taacgcacct
     9001 tactttccac atagcggaac tgcaccaccg tcagaatgat gacgaggaac atcaacacca
     9061 ccgactgcgc ggcggacgcc gagagatcca ggccggtaaa cccttcgcaa taaatcttat
     9121 aaatcagcgt cgtggtggct tgtaccggcc cgccggcggt cgcggcgtca atcaccggga
     9181 aggtgtcgaa aaaggcatac accaggttga ccaccagcag gaagaaactg accggcgcaa
     9241 taagcggcaa agaaagccgg aagaaacgac gaatcggccc ggcgccgtca atggccgccg
     9301 cttccaccag cgagcgggga atagattgca gcgcggcaaa gaagaataaa aagttgtaac
     9361 taatctgctt ccagactgac gcaaatacca ccaggaacat cgcctgaccg ctgttttgcg
     9421 cgtggttcca gtcatagccg aattcgccga ggaaatgggt gattaatccc cgccccgggt
     9481 taaacaggaa aatccacaat acggcggcga cggcgggcgc gacggcataa ggcagcagca
     9541 tcagcgtctg ataaaaacgg ctgccgcgca ccacgtaatc caccagggcg gcgaaaaaca
     9601 atgagaccag caggccgcta aacgtgacca gcgcgctgaa tttaatcgtc gtccagaagg
     9661 cgtcgagata ataactgtcg tgaaaaagcg cgacgaaatt ctccagcccg acaaattggc
     9721 tggaaaaacc aaacggatcg acgctttgca gcgaatacca cagcgcttcg cccgcaggcc
     9781 agataaagaa aataacggtg ataaccaact gcggagcaac cagtaaatac ggcagccagc
     9841 gcgagcggaa caccggacgg gatgatgaca tgaaggttct tttcctggaa ggtgccggat
     9901 ggcggtgcaa gcaccttatc cggcctacaa acgctgtagg cctgataagc gcagcgccat
     9961 caggcactta tacacttaag atttgctcgc tttctcaaaa cgacgcagta actgattccc
    10021 gcgatccacc gcggtatcca acgcctgttg tggggttttc ttcccggtcc agacgctttc
    10081 cagctcttcg tccacgatgg tacgaatctg cggcatattg cccagacgca agcctttggt
    10141 gaagggtaac ggcggcttat tcaacatctg gcgagtggcg atatccgcac cggggttttt
    10201 atcgtaataa ccctgctctc gggtcagctc gtaggcggcg gtggtaatcg gcaggtagcc
    10261 ggttttttga tgccattcag cagcgttttc cggttttgcc aggaagtcga ggaatttggc
    10321 gacgccggta taggtttctt tatctttacc ctgcatgacc cataggctgg ctccgccgat
    10381 aatggcgttt tgcggcgcgc ccttgatatc agcgtcatac ggcatcatac ccacgccata
    10441 gttaaatttg gcatactggc ggatattggc gagcgagccg gaggacgcgg ttgtcatcgc
    10501 gcagtcaccg ttataaaact tctcggtaga ctcgtcctta cgcccaacat agctaaaatc
    10561 gcctttctta ttcatctctt ccagcagcgc gatatgtttc acctgctctg gcttattaaa
    10621 ctccagcacc gcatctgtac cgtcaaagcc attgttttta ctggcgaagg ggagaccgtt
    10681 ccaggcgctg aagttttcca gttggatcca gccttgccag ccgctggcgt aaccgcattt
    10741 catgcctgcc gctctcaatt tcgcggtata gtcagccagc tcctgccaag ttttcggcgg
    10801 ctgctccgga tctaaaccgg ctttcttaaa ggcgtctttg ttgtagtaca gtaccggcgt
    10861 ggagctgtta aagggctggg agagcagatg cccgctttta gcatcggtgt agtagcctgc
    10921 aacggttggt acaaactggg actcgtcaaa gttaataccg gcgtctttaa acacttcata
    10981 aaccggctta atggctttcg aggccatcat ggtcgctgtc ccaacctcat aaacctgcaa
    11041 tattgccggc gcgttgccgg tacggaatgc cgcgatcccg gcgctcaggt tctgttcata
    11101 gttcccctta tagaccggaa cgattttgta atccggattg gcctggttga aacgttgcgc
    11161 cagtgaatca acttctttgc ctaactcccc ttccattgaa tgccagaatg gaatagtggt
    11221 gacggccaac gcctgacccg taaatgccag actcagcgcc agtcctaaag ctgtatgtcg
    11281 taacgatatc atcggttatc tctctttttg tgccgggatg cgcgatatca cgcgttttat
    11341 gttcgcgggg gtaacatgac atgctcgaat gacagaaaaa taactttttt attacaaaaa
    11401 aagatagtaa ggcgacagag agatggcaag gcagtgaaag cgccggaaaa gaaaagtggg
    11461 agctacggca cgtctgacag cgtaatgctg accagacatg cgttatttgg ctggcgtcag
    11521 cagttaatca cgatgagaat actttttgta cagattttgt aagcgccgct gatctcgccg
    11581 ctcgcgttca cgctgaatgt cggatttttc atcctcccac gttgcacaat ccggatgatg
    11641 acgcacttcg caggtcgttg cggccagtgg ataaggcgtt gcggtttctt cttgccagat
    11701 agcaggatcg cggggatcaa aatcgtttga ggttaaggcg ttaacactga acgaagccgc
    11761 gaacaacagc gttcccatta tgcaggcgcc tgaacgtatc atccttgctc cttcttcggt
    11821 ggttatagtt gataactatt ctcaactata acatattggt acgaaaaatg ttctactgat
    11881 ttgccgaatg ccgagtaatc cgccaggtcc ggtaagcggt agcgccaccg ggcgcgtttg
    11941 ccagatggca gctgtaaact gcgccttatc cgcccagata ggcgctgcgc accgcttcgt
    12001 tcgccagcag cgcatcaccg gtatcggata gcaccacgtg gccgttttcc agcacataac
    12061 cgcggtcggc gagcttcagc gcctggttag cgttttgctc gacaaggaag atggtcatac
    12121 cctgctcgcg caactgctca atggtgtcga agatctgctg gatgatgatc ggcgccagcc
    12181 ccagcgacgg ttcatccagc agcaacaggc gcggctggct catcagcgcg cgaccaatcg
    12241 ccagcatctg ctgttcgccg ccggacatgg tgcccgctcg ctggatacgg cgttcatgca
    12301 ggcgcggaaa cagctcgtac acccatttga tacgctcctg aaaccgatcg cgctcggcaa
    12361 aaaaaccgcc catcgccagg ttctcttcca ccgtcatccg cgagaagacg cgccgccctt
    12421 ccggcactat cgccaccgct tcacgcatga ttttcgccgt ctgccagtcg gtgatgtctt
    12481 taccgtcaaa caccacccgt ccgctggagg cgcgcggatc gccgcacaag gtgccaagca
    12541 gcgtcgtttt ccccgcgccg ttagcgccaa tcagggtaac gatttccccc tggttgatgt
    12601 gcagactgac gtcgtgcagc gcctgaatct tgccgtagtg ggcgctgact ttttcaaacg
    12661 ttaacatcgt tttttccatc ttatgcctca cccagataag cgcggatgac gtccgggttg
    12721 ttgcggatct cttccggcgt gccgttcgcc agcggcgtgc cctggttcac cacgtaaatg
    12781 cgatcggaaa tgcccatcac cagcttcata tcgtgttcaa tcagcaagat agtggtgttg
    12841 tgatggttac gtagttcggc aatcagctca tccagctctt tggtctcttt cgggttaagg
    12901 ccggccgccg gttcgtcgag catcagaatt tctggctgcg tcaccatgca gcgggcaatc
    12961 tccagccggc gctggtcgcc gtaggccaga ttactggcct ggcggttggc atgttccagc
    13021 aggccaatac gctcaagcca ggtcgccgcg cggtccagcg cttcactttg cgcgcggcgg
    13081 aaagcgggcg ttttcaacag gccggaaaag aggcccgttt tcagttgctg gtgctgcgcc
    13141 accagcaggt tttcaatcac cgtcatttcg cgaaacaggc gcacatgctg gaaagtgcgt
    13201 accacgccca tgcgggcgat ctgctggccc ggcaatcctt ccagatgccg ctcgcgcaac
    13261 gtgatcgtac cgcctgtcgg cttataaaaa ccggtcaggc agttaaacac cgtcgtttta
    13321 cccgcgccgt tagggccaat cagcgacaca atttcccgct cacgcaattc cagcgataca
    13381 ttgttgaccg ccagcaaacc gccaaagcgc atcatcaggc cgttaaccgc taataatggc
    13441 tgactcatgc ctgctctcct ttcgcctgac cacttttcag cttcaactgc ggacgcgtca
    13501 tcggcagcaa tccctgcggg cgccagatca tcatcaacac cattaaaccg ccgagcatca
    13561 acatgctgta ttcgttgaaa tcgcgcatca actcgcgcga caccaccaac agaaccgccg
    13621 ccaggatcac cgcaaactgc gagcccattc cgcccagcac cacaatcgcc agcacgaagg
    13681 cggattcggc gaaagtgaag gattccgggc tgacaaagcc ctggcgggcg gcaaacaacg
    13741 tcccggcgaa accggcaaac gcggcgctga tagtaaaagc ggtcagcttg atgcgcgtcg
    13801 ggcttaaacc taatgagcga caggcgatct catcttcacg caacgcttcc cacgcccggc
    13861 ccagcggcat acgcagcagg cggttaatga caaacagcga caggaccacc agcaacaggg
    13921 ccaccagata gaggaaaatg acccggtcgg atgggtcgta cttcacgcca aagaaattgc
    13981 tgaaggtatc ccagccgcct tctcgggtgt tgcggctaaa ctccagacca aacagcgtcg
    14041 gtttggggat ctggctgatg ccgttcgggc cgccggtaat ttcagtgttg ttgagcaaca
    14101 ggatacggac gatttcgccg aagccgagcg tcacaatcgc cagatagtcg ccgcgcaggc
    14161 gcagtaccgg gaagccgagc aggaaaccgg cggcggcgga gaccagtccc gccagcggca
    14221 ggcaggtcca gaaacccaaa ccgtaatagt ggttaagcag cgcaaaggta taagcgccga
    14281 tggcgtaaaa gccgccgtag cccaatacca gcaggccgga cagccccacc accacgttca
    14341 gccccagacc gaggatgata taaatcatgg tcatagtggc gatatcgacg ctaccgcgcg
    14401 acaccataaa cggccacgcc acggcgataa ccaacagcgc catcagaaac agcttttgct
    14461 taacggtaga gccatcgatc gccggcagaa taaacttcgg tccggagacg tgcttcaccg
    14521 ctttctggaa catcggacgc agcaactgaa agaaaaaaac cactgccgta ccgataaaga
    14581 tccactgcca gcggatgtcg gcggcggtat ccaccaccag tttggtgccg tccagctcca
    14641 gttgtacgcc cataaagacg ccagccagaa cgaagaacat cgccgcagag aacagagcca
    14701 tcgcaatatg catcggtttc atactttctc tacctccgga cgccccagga taccggtcgg
    14761 catcaccagc agtaccagaa tcagcagagc gaacgacacg acatctttat attcggtact
    14821 taaatatgca gacgagagcg cttcggcgac gcccaaaatc agaccgccga tcatcgcgcc
    14881 cggaatgctg ccaataccgc ccagcaccgc cgcggtgaac gctttcatcc cggccataaa
    14941 accgatgtag gggttaatca cgccatagaa ctgaccgagc agcacgcccg ccaccgccgc
    15001 cattgccgcg ccgataacaa acgttagcgc aatgacgcgg tcggtattaa tgccgagcag
    15061 gctggccatt ttcagatcct ccgcgcaggc gcggcaggcg cggcccatcc gggagtagcg
    15121 aatgaaaatg gtgagcgcca gcatagccag aaaggtgact atccagataa ccgcctgcat
    15181 ggtggtgatg gacgcggaaa agttttcgct gctgcccaca atccactggc cgttaaacag
    15241 gctgggtaac gccacgtcgc gcgaaccttc cgtcaggctg acgtagtttt gcagaaagat
    15301 ggacatcccg atggcggaaa tcagggcgat caggcgcttg gaattgcgca caggccggta
    15361 agcgactcgc tcgatactcc agccgtaggc gctggcaata ataatcgcgc cgataaatcc
    15421 ggcggccacc agtagccaac tggtgtctat tcccatcatc attagcgcgg cgatgatcat
    15481 aaaagagacg tagctgccga tcatatacac ctcgccatga gcgaagttga tcatgccgat
    15541 aatgccgtac accatcgtat aaccgatagc aatcagcgcg taggtgctcc ccagcgtgac
    15601 gccgttaaac atctgctgca agaaatagag aaactgctcg gacataaggt aaccttttta
    15661 aacccgcccg gcgtgcgggc ggtgggataa cttatcttct ggcattactt cgcgacggtt
    15721 gacgagccgt cggcgtgcca ctggaagacg ccaaattcaa atcccttaag atcgcctttt
    15781 tcatcccatt tcagcggccc aataacggta tcagccccgt tcgctttaag atctttcacc
    15841 agatccagcg gagcatggct ggcgctacgc gtcattgcgg tcgccagcga ctggacggcg
    15901 gcgtaggtga tccagacata cggaccgctg ggatctttct tgtcggcttt cagcgcctcg
    15961 acaatcgctt tattcgccgg gtcctggtca taacgttttg gcatcgtcac caacatgcct
    16021 tccgccgcac cgcccgcaat attggacagc gacgcgttac ccacgccttc cggccccata
    16081 aattgcgttt tcaggccatt agcccgcgcc tggcgcagca tctgccccat ttccgggtag
    16141 tagccgccgt aatacacaaa gtcgatattc tctttttgca agcgagcaat cagggcggag
    16201 aaatcttttt cgccggcggt aataccatca aaaaagacaa tattggcatt gccctgcttc
    16261 aggccatcct gcacggagcg cgccagtcct tcgccgtatt gctgtttatc gtgaatgata
    16321 gcgatgcgct gcggtttcac cgtttccagg atgtatttcg cggccgttgg cccctgggag
    16381 gagtccaggc cggcggtacg cataatgtac tgatagccgc gctgggtcag ctccgggtta
    16441 gtcgcccccg gggagatcat cagaatacct tcatcttcat agatatcgga tgctggctga
    16501 gtagaagaag aacacaagtg accaataacg tactgaatac cgtcgttaac gattttgttg
    16561 gccaccgcca ccgcctgttt tggatcgcag gcatcatcgt actctacgcc gaccagctta
    16621 tcgcctttaa taccgccttt agcattgatg tctttaatgg cctggcgcgc gccgttaaat
    16681 tccatatcgc cccattgcgc taccgggccg gacatcgccc cgactatggc gactttaata
    16741 tcatctgcca ttgccccctg cgagactgct aatgcaacaa tccctgcgat tattgttttc
    16801 gctttccgtt tcatgtgcct gtatccccat tcgtgatgtt ata
//
LOCUS       DAJVBX010000094        16636 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.094, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000094 DAJVBX010000000
VERSION     DAJVBX010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 16636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16636
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.094"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            126..1532
                     /gene="chiP"
                     /locus_tag="OPV72_002572"
     CDS             126..1532
                     /gene="chiP"
                     /locus_tag="OPV72_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitoporin"
                     /protein_id="HCR9914835.1"
                     /translation="MRTFSGKRSTLALAIAGITAMSGWIVVPQAQASGFFDDSTLTGG
                     IYYWQRERDRKDVTDGDKYKTNLSHATWNANLDFQSGYAADMFGLDIAAFTAIEMAEN
                     GDSGHPNEIAFSKKNKGYDEDYSGDKSGISLYKAAAKFKYGPVWARAGYIQPTGQTLL
                     APHWSFMPGTYQGAEAGASFDYGDAGALSFSYMWTNEYKAPWHTEMDKFYQADKKTNV
                     DYLHSIGAKYDFKNDLVLEAAFGQSEGYVDQYFAKASYKFDLGGNPFTTSYQFYGARD
                     KVDDRSVNDIYDGTAWLQALTFGYKVAEVVDLRLEGTWVKADGQQGYFLQRMTPTYAS
                     SNGRLDIWWDNRSDFNANGEKAVFFGAMYDLKNWNLPGWAVGASYVYAWDAKPATWQS
                     NPDAYYDKNRTIEESSYSLDAVYTLQEGRAKGTMFKLHFTEYDNHSNIPSWGGGYGNI
                     FQDERDVKFIVIAPFTIF"
     gene            1582..1914
                     /locus_tag="OPV72_002573"
     CDS             1582..1914
                     /locus_tag="OPV72_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCR9914836.1"
                     /translation="MKKILLIASMTAGLTACASSPAPEEDSRLKEAYSACINTAQGSP
                     EKIEACQSVLNVLKKERKHQQFANEESVRVLDYQQCIQATRTGNDQAVKADCDKVWQE
                     IRSHNNVQ"
     gene            complement(1963..3267)
                     /gene="tcuC"
                     /locus_tag="OPV72_002574"
     CDS             complement(1963..3267)
                     /gene="tcuC"
                     /locus_tag="OPV72_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tricarballylate/proton symporter TcuC"
                     /protein_id="HCR9914837.1"
                     /translation="MAQHTPATSRAGTFGAILRVTSGNFLEQFDFFLFGFYATYIART
                     FFPAESEFASLMLTFAVFGSGFLMRPVGAIVLGAYIDRIGRRKGLMVTLAIMGCGTLL
                     IALVPGYQTIGLAAPALVLLGRLLQGFSAGVELGGVSVYLSEIATPGNKGFYTSWQSA
                     SQQVAIVVAALIGYSLNITLGHDAISEWGWRIPFFIGCMIIPLIFVLRRSLQETEAFL
                     QRKHRPDTREIFATIAKNWRIITAGTLLVAMTTTTFYFITVYTPTYGRTVLNLSARDS
                     LIVTMLVGVSNFIWLPIGGAISDRIGRRAVLMGITLLALITTWPVMQWLTAAPDFTRM
                     TLVLLWFSFFFGMYNGAMVAALTEVMPVYVRTVGFSLAFSLATAIFGGLTPAISTALV
                     KLTGDKSSPGWWLMCAALCGLAATAMLFVRLSRGYIAAENKA"
     gene            complement(3318..4457)
                     /gene="tcuB"
                     /locus_tag="OPV72_002575"
     CDS             complement(3318..4457)
                     /gene="tcuB"
                     /locus_tag="OPV72_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tricarballylate utilization protein TcuB"
                     /protein_id="HCR9914838.1"
                     /translation="MKQLEKLIIEATVLTEPEAEVERVMQVCNACRYCEGFCAVFPAM
                     TQRLEFGKADIHYLANLCHNCGACLHACQYAPPHEFAINVPKAMAQARLETYQQYAQP
                     AAFGALYRRAGITVALALIVGLTLFLLLAMALKGSLIHPPLAGDFYQIFPHSLLAWMF
                     GSVFVLAIGLLMAGVISFWREISPGVPRSAEIAEASHNALTLKYLDGGHGKGCNEADD
                     AFTLLRRRFHHFTFYGFMLCFAATVVATGYHYVAGWEAPYPFFSLPVMLGTLGGIGLL
                     IGPAGLLWLNLRRSPLHSDARQKPMDRGFILLLFLTSLTGLALLAGRDTSGMGILLAL
                     HLGVVMALFLTLPYGKFAHGFFRCAALLKWAVEKRRGKHAGDTGN"
     gene            complement(4444..5847)
                     /gene="tcuA"
                     /locus_tag="OPV72_002576"
     CDS             complement(4444..5847)
                     /gene="tcuA"
                     /locus_tag="OPV72_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent tricarballylate dehydrogenase
                     TcuA"
                     /protein_id="HCR9914839.1"
                     /translation="MVDVLVIGGGNAALCAALTAREAGASVLLLEAAPREWRGGNSQH
                     TRNLRCMHDAPQDVLVESYPEEEFWQDLWRVTDGNTNEALARLVIRTSSQCRDWMRKH
                     GVNFQPPLSGALHVARTNAFFMGGGKALVNAYYRSAERLGVQIRYNTPVHALELHDGE
                     FVAALAGSERITAKACVLAAGGFESNREWLREAWGENARGEWPADNFLIRGTRFNQGV
                     LLKFMMDAGADIIGDPSQSHCVAIDARAPLYDGGICTRVDCVSLGIVVNRDAERFYDE
                     GEDFWPKRYAIWGRLVAQQPGQIGYSIIDSKAIGHFMPPVFPGAQANTLAELACQLGL
                     DAEKFTHTVTQYNQACQPGHFDHTLLDDCATKNLTPAKTHWARPLDAPPYYGYALRPG
                     ITFTYLGLKVNERAAVHFAGHPSRNLFVAGEMMAGNVLGKGYTAGVGMSIGTTFGRIA
                     GIEAARAAHKEAQHETA"
     gene            complement(5945..6871)
                     /gene="tcuR"
                     /locus_tag="OPV72_002577"
     CDS             complement(5945..6871)
                     /gene="tcuR"
                     /locus_tag="OPV72_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tricarballylate utilization LysR family
                     transcriptional regulator TcuR"
                     /protein_id="HCR9914840.1"
                     /translation="MELRQLRYFVRIIETGSMGSAAQDLDIGVSALSQQMSRLENELA
                     IRLLQRTSRGVTPTNAGLAFYSQAQLALRHADDAILAAREARLSGHVSVGMAPSTASI
                     LGIPFIHAMQENYADVRLHVVESLSGNLERMINTRQIDLAVVFQKDKILRWSARPILE
                     EQLFLIGSHALLAALPDNPITPEQLAGIPLIMPSQGHGLRGRLDAVCKEHALNVEIVA
                     EIDGLALLMRAVRDGLGATLQPGAAISHLDNDALRVIGVHNPVLSRPNFLVSLSDDEL
                     TPAGLAARVVLTKVMRQLVDAGEWPGATLYAY"
     gene            complement(6986..7438)
                     /gene="fur"
                     /locus_tag="OPV72_002578"
     CDS             complement(6986..7438)
                     /gene="fur"
                     /locus_tag="OPV72_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric iron uptake transcriptional regulator"
                     /protein_id="HCR9914841.1"
                     /translation="MTDNNTALKKAGLKVTLPRLKILEVLQEPDNHHVSAEDLYKRLI
                     DMGEEIGLATVYRVLNQFDDAGIVTRHNFEGGKSVFELTQQHHHDHLICLDCGKVIEF
                     SDDSIEARQREIAAKHGIRLTNHSLYLYGHCAEGDCREDEHAHDDATK"
     gene            complement(7431..7516)
                     /locus_tag="OPV72_002579"
                     /pseudo
     CDS             complement(7431..7516)
                     /locus_tag="OPV72_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001491546.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ryhB-regulated fur leader peptide"
     gene            complement(7720..8250)
                     /gene="fldA"
                     /locus_tag="OPV72_002580"
     CDS             complement(7720..8250)
                     /gene="fldA"
                     /locus_tag="OPV72_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin FldA"
                     /protein_id="HCR9914842.1"
                     /translation="MAITGIFFGSDTGNTENIAKMIQKQLGKDVADVHDIAKSSKEDL
                     EGYDILLLGIPTWYYGEAQCDWDDFFPTLEEIDFNGKLVALFGCGDQEDYAEYFCDAL
                     GTIRDIIEPRGATIVGHWPTAGYHFEASKGLADDDHFVGLAIDEDRQPELTAERVEKW
                     VKQVSAELHLGDILNA"
     gene            complement(8401..8694)
                     /gene="ybfE"
                     /locus_tag="OPV72_002581"
     CDS             complement(8401..8694)
                     /gene="ybfE"
                     /locus_tag="OPV72_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA regulated protein"
                     /protein_id="HCR9914843.1"
                     /translation="MAKEQTDRTTLDLFAHERRPGRPKTNPLSRDEQLRINKRNQLKR
                     DKVRGLKRVELKLNAQAVDALNELAEARNISRSELIEEILMKQLMALRGQGLV"
     gene            complement(8828..9598)
                     /gene="ybfF"
                     /locus_tag="OPV72_002582"
     CDS             complement(8828..9598)
                     /gene="ybfF"
                     /locus_tag="OPV72_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HCR9914844.1"
                     /translation="MKLNIRAQSAQNLHNNSPIVLVHGLFGSLDNLGVLARDLVTDHD
                     IIQVDMRNHGLSPRDPVMDYPAMAQDLLDTLDAQQIEKATFIGHSMGGKAVMALTALA
                     PDRIDRLVAIDIAPVDYHVRRHDRIFAAINAVSESDATSRQQAAGIMRQHLNKEGVIQ
                     FLLKSWAEGEWRFNVPVLWEQYPHIVGWETIPPWEHPALFIPGGNSPYVTEAYRDALL
                     AQFPLARAHVIAGAGHWVHAEKPEAVLRAIRRYLHDKR"
     gene            9783..10325
                     /gene="seqA"
                     /locus_tag="OPV72_002583"
     CDS             9783..10325
                     /gene="seqA"
                     /locus_tag="OPV72_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation negative regulator SeqA"
                     /protein_id="HCR9914845.1"
                     /translation="MKTIEVDDELYSYIASHTKHIGESASDILRRMLKFSATTQPTAS
                     AVKGTPAAQPVAEAKPVNPVKDKVRAMRELLLSDEYAEQKKAVNRFMLILTTLYSLDH
                     HAFAEATESLHGRTRVYFAADEQTLLKNGNQTKPKHVPGTPYWVITNTNTGRKCSMIE
                     HIMQSMQFPAELIEKVCGTI"
     gene            10350..11990
                     /gene="pgm"
                     /locus_tag="OPV72_002584"
     CDS             10350..11990
                     /gene="pgm"
                     /locus_tag="OPV72_002584"
                     /EC_number="5.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-glucose phosphate-specific
                     phosphoglucomutase"
                     /protein_id="HCR9914846.1"
                     /translation="MAIHNRAGQPAQQSDLINVAQLTAQYYVLKPEAGNAEHAVKFGT
                     SGHRGSAGRHSFNEPHILAIAQAIAEERAKNGITGPCYVGKDTHALSEPAFISVLEVL
                     AANGVDVIVQENNGFTPTPAVSNAILVHNKKGGPLADGIVITPSHNPPEDGGIKYNPP
                     NGGPADTNVTKVVEDRANALLADGLQGVKRISLDAAMASGHVKAVDLVQPFVEGLADI
                     VDMAAIQKAGLTLGVDPLGGSGIEYWKRIAEHYKLNLTLVNDQVDQTFRFMHLDKDGA
                     IRMDCSSECAMAGLLALRDKFDLAFANDPDYDRHGIVTPAGLMNPNHYLAVAINYLFQ
                     HRPLWGKDVAVGKTLVSSAMIDRVVNDLGRKLVEVPVGFKWFVDGLFDGSFGFGGEES
                     AGASFLRFDGTPWSTDKDGIIMCLLAAEITAVTGKNPQEHYNELAARFGAPSYNRLQA
                     AATSAQKAALSKLSPEMVSASTLAGDPITARLTAAPGNGASIGGLKVMTDNGWFAARP
                     SGTEDAYKIYCESFLGEEHRKQIEKEAVEIVSEVLKNA"
     gene            complement(12105..12590)
                     /locus_tag="OPV72_002585"
     CDS             complement(12105..12590)
                     /locus_tag="OPV72_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HCR9914847.1"
                     /translation="MSNPEREVTDIAEILAILSKHEVCRIGFNDNLCPYVVPVNFGYE
                     YQNGRWIFYFHGARTGKKMRLLRKNPAVCIEMDGDHALLRADDPCDYSYAYTSVFATG
                     LASILQTREEMRHGLDVIMRQTDPGKTFSYREDMMKAVCVVRIECDALTCRRHLATQS
                     E"
     gene            complement(12655..13974)
                     /gene="potE"
                     /locus_tag="OPV72_002586"
     CDS             complement(12655..13974)
                     /gene="potE"
                     /locus_tag="OPV72_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine-ornithine antiporter"
                     /protein_id="HCR9914848.1"
                     /translation="MSKPKSNKMGVVQLTILTMVNMMGSGIIMLPTKLSEVGTISIIS
                     WLVTAVGSMALAWAFAKCGMFSRKSGGMGGYAEYAFGKSGNFMANYTYGVSLLIANVA
                     IAISAVGYGTELFGAALTPLQIGLATIAVLWVCTIANFGGARITGQISSVTVWGVIIP
                     VVGLCIIGWFWFSPSMYVASWNPHHVPFFSAVGSSIAMTLWAFLGLESACANADVVEN
                     PEKNVPIAVLGGTLGAAVIYIVSTNVIAGIVPNMDLANSTAPFGLAFAQMFTPAVGKV
                     IMALMVMSCCGSLLGWQFTIAQVFKSSADEGYFPKVFSRVTKVDAPVQGMLIIVIIQT
                     GLSLMTISPSLNSQFNVLVNLAVVTNIIPYILSMAALVIIQKMANVPSSKAKVANFVA
                     FVGAMYSFYALYSSGEEAMLYGSIVTFLGWTLYGLVSPRFELKNKHG"
     gene            complement(13971..16039)
                     /locus_tag="OPV72_002587"
                     /pseudo
     CDS             complement(13971..16039)
                     /locus_tag="OPV72_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459686.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine decarboxylase"
     gene            complement(16422..16523)
                     /locus_tag="OPV72_002588"
                     /pseudo
     CDS             complement(16422..16523)
                     /locus_tag="OPV72_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001312672.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2618 domain-containing protein"
BASE COUNT         4063 a         4371 c         4457 g         3745 t
ORIGIN      
        1 attcgcatcg cgaaaaatag tctatttaac gtagtaaatg aggtttctca gcgctacttt
       61 ttatttttat tttttcgctg ttcgcttttg tcggcagcaa tttatacgtc aaagaggatt
      121 aacttatgcg tacgtttagt ggcaaacgta gtacgctggc tctggctatc gccggtatca
      181 cagcaatgtc ggggtggatc gttgttccgc aggcgcaagc ctccggcttt ttcgacgact
      241 ccacgttaac gggcggcatc tattattggc agcgtgaacg cgatcgcaaa gatgtgaccg
      301 acggcgacaa atataaaact aacctttctc atgcgacctg gaacgctaac ctggattttc
      361 agtctggtta cgctgcggat atgttcggtc tggatatcgc ggcgtttacc gcgattgaaa
      421 tggcagaaaa cggcgacagc ggtcatccaa acgaaattgc cttctcgaaa aagaataaag
      481 gctacgacga agactattcc ggcgataaga gcggtatcag tctttataaa gccgccgcga
      541 aatttaaata tggcccggtc tgggcgcgcg ccggttatat tcagcctacc ggtcagacgc
      601 tgttagcgcc gcactggagt tttatgccgg gtacctatca gggtgcggaa gccggcgcca
      661 gttttgacta tggcgatgcg ggcgcgttaa gtttttccta catgtggact aacgaatata
      721 aagcgccgtg gcataccgaa atggataagt tttatcaggc ggataaaaaa accaatgtag
      781 actatctcca ctccatcggc gcgaagtacg acttcaaaaa tgatctggtg ctggaagcgg
      841 cgtttggtca gtccgaaggc tatgtcgatc aatatttcgc aaaggccagc tataaatttg
      901 atttaggcgg caatccgttc accaccagtt accagttcta cggcgcgcgc gacaaagtag
      961 acgatcgcag cgtgaatgac atttacgacg gtacggcctg gctgcaggcg ttgaccttcg
     1021 gctacaaagt cgcggaagtg gttgacctgc gtctggaggg cacctgggtg aaagcggacg
     1081 gtcagcaggg ctattttctg caacgtatga cgccaaccta cgcctcttca aacggtcgtc
     1141 tggatatctg gtgggataac cgctccgact ttaacgctaa cggtgaaaag gcggttttct
     1201 tcggcgcgat gtatgacctg aaaaactgga atctgccggg ctgggctgtg ggcgcgtctt
     1261 acgtttacgc ctgggatgct aaaccggcaa cctggcaaag taacccggat gcttactacg
     1321 acaaaaaccg cactatcgaa gagtcctcat acagtctgga tgcggtctat accctgcagg
     1381 aggggcgtgc caaaggcacc atgttcaaac tgcacttcac cgaatatgac aaccactcca
     1441 atattccaag ctggggcggt ggttacggca acatcttcca ggatgaacgt gacgtgaaat
     1501 ttatcgttat tgcgccattc actattttct gatgtcagat gcggcaggct gccggtctgc
     1561 cgcgctgttg aggaacgacc tatgaaaaaa attttactca tcgccagcat gaccgccggt
     1621 ttgacggcct gcgcgtcatc acccgcgccg gaagaagata gtcggctgaa agaggcgtac
     1681 agcgcctgta tcaataccgc acagggctcg cctgagaaga tagaggcctg ccaaagcgta
     1741 ctgaatgtcc ttaaaaaaga gcgcaaacat cagcaatttg ctaacgaaga aagcgtgcgg
     1801 gtactggact atcagcagtg cattcaggcg acgcgcacgg gtaacgatca ggcggtcaag
     1861 gctgactgcg ataaggtctg gcaggaaatt cgcagtcata ataacgtgca ataaaaccct
     1921 gccttgccac ccacgggcga atgttttccg cctgtggttt tttcaggctt tattttctgc
     1981 cgcgatatag ccgcgactca gacgtacaaa cagcatcgcc gtcgcggcaa gtccacataa
     2041 cgctgcgcac atcagccacc agccgggcga gcttttatcg ccggttaact ttaccagcgc
     2101 ggtagagatg gccggcgtca ggccgccaaa aattgccgtc gccaggctaa aggccagcga
     2161 gaaaccaacg gtacgcacat agactggcat cacttcggtt aacgccgcga ccattgcgcc
     2221 gttatacatg ccaaaaaaga aagagaacca cagcagtacc agcgtcatgc gggtaaagtc
     2281 gggcgcggcg gtcagccact gcatgacggg ccaggtggtg atcagcgcca gcaacgtaat
     2341 gcccattaac acggcgcgac ggccaatccg gtcggaaatc gcgccgccaa tgggtaacca
     2401 gataaaattg gacaccccca ctaacatggt gacgatcaaa ctgtcccgcg cgctgagatt
     2461 aagcacggtt ctgccatagg tcggcgtata aacggtgata aaataaaacg ttgtggtggt
     2521 catcgccacc agcagcgttc cggccgtaat aatgcgccag tttttggcga tagttgcaaa
     2581 aatttcccta gtgtcggggc gatgcttgcg ttgtaaaaac gcttctgttt cttgtaatga
     2641 acgacgtaaa acaaaaatca gcggaatgat catacagccg ataaagaacg gaattcgcca
     2701 gccccactcc gatatcgcgt cgtgtcccag cgtgatattc aggctataac caatcaacgc
     2761 ggcgacaacg atcgcaacct gctgactggc ggattgccag ctggtataaa accctttatt
     2821 gcctggcgtt gcgatttcgg acagatagac cgagacgccg cctaactcaa cgcccgcaga
     2881 aaatccttgt aataaccggc ccaacaacac caacgcaggc gctgccaggc cgatcgtctg
     2941 gtagccgggg acgagggcga tgagcaacgt accgcagccc ataatcgcca gcgtcaccat
     3001 cagcccttta cgacgtccga ttctgtcaat ataggcgcca agcacaatcg cgccgacggg
     3061 gcgcattaaa aaaccggagc caaagacggc aaaggtcaac attaatgagg caaattcgct
     3121 ttccgccgga aaaaacgttc tggcgatata ggtggcgtaa aatccgaaca agaaaaaatc
     3181 aaactgttca aggaaattgc cgcttgtcac gcgcagtatt gcgccgaacg tgccggcgcg
     3241 cgatgttgca ggtgtgtgtt gtgccatagg gtttgctctc cactgtcttt attgttttat
     3301 aggtaagatg ttgcgggtca gttgcctgta tcccccgcat gttttccgcg tcgcttctca
     3361 actgcccatt tgagtaaggc cgcgcagcgg aaaaatccgt gggcgaattt tccgtaggga
     3421 agggtgagaa agagcgccat caccacgcct aaatggagcg ccagcagtat gcccattccg
     3481 ctggtgtctc tgcctgccag cagcgccagc ccggtaagac tggttaagaa cagcagcaga
     3541 ataaagccgc gatccatggg tttctggcgc gcatcgctat gtaacggcga ccgccgcaga
     3601 ttgagccaca gtagcccggc cgggccgata agcagaccga taccgcccag cgtgccgagc
     3661 atgaccggca ggctaaagaa cgggtagggc gcttcccaac cggcgacgta gtgatagccc
     3721 gtcgccacga ccgtggcggc aaaacagagc ataaaaccgt aaaaggtaaa gtgatgaaag
     3781 cgacggcgca gcagcgtgaa cgcatcgtcc gcttcgttac agcctttgcc gtgaccgccg
     3841 tcgagatatt tcagcgttaa cgcattgtgc gacgcttccg caatctccgc cgaacgcggt
     3901 acacccggcg agatctcacg ccagaagctg attacgcccg ccataagcaa accgattgcc
     3961 agcacaaaaa ctgagccaaa catccatgcc agcaggctat gcggaaaaat ttgatagaag
     4021 tcaccggcca gcggcggatg aatcagcgac cctttcagcg ccatcgccag taataaaaag
     4081 agcgtcagac cgactatcag cgccagcgcg acggtgatcc ccgcccgacg gtataacgcg
     4141 ccaaaagcgg cgggctgggc atactgttga tacgtctcca ggcgggcttg cgccatcgct
     4201 ttcggcacgt taatggcaaa ttcatggggc ggcgcgtact ggcacgcgtg caggcaggcg
     4261 ccgcagttat gacataaatt cgccagataa tgaatatcgg ctttaccgaa ttcgagccgc
     4321 tgggtcatcg ccggaaatac cgcgcaaaaa ccttcgcagt agcgacacgc gttacacact
     4381 tgcatgacgc gttcgacctc ggcttccggt tcggtaagca cggtggcctc aatgattaat
     4441 ttttcaagct gtttcatgct gcgcctcctt gtgcgccgcg cgagcggctt ctattcccgc
     4501 aatgcggcca aaggttgtgc cgatagacat gcctacgcct gcggtatacc ccttgcccag
     4561 aacatttcct gccatcatct cgccggcaac aaacaggttg cggcttggat gaccggcaaa
     4621 atgcaccgcg gcacgttcat tgactttcag gcccaggtag gtaaacgtga tgccgggtcg
     4681 cagcgcataa ccgtagtagg gcggcgcatc aagcgggcgc gcccagtggg ttttcgccgg
     4741 cgtcaggttt ttggtggcgc agtcatcaag caaggtatga tcaaaatgac cgggctggca
     4801 ggcctggtta tactgcgtga cggtatgggt aaatttttcc gcgtccagcc ccaactggca
     4861 ggccagttca gccagcgtat tggcctgcgc gccaggaaaa accggcggca taaagtggcc
     4921 aatggctttg ctgtcaataa tcgaatagcc aatttgtcct ggctgttgag ccaccagccg
     4981 cccccaaatg gcgtaacgct tcggccagaa atcttcgcct tcatcataaa aacgctcggc
     5041 gtcgcgattc acgacaatac ccagcgatac gcaatccacg cgagtacaaa taccgccgtc
     5101 gtacagcggc gccctggcat caatcgctac gcagtgcgac tgggacggat cgccaatgat
     5161 atccgcgccg gcatccatca taaatttgag taatacgccc tggttaaaac gcgtgccgcg
     5221 aatcaggaaa ttatccgcgg gccattcgcc gcgggcgttt tctccccagg cctcccgcag
     5281 ccattcacgg tttgattcga aaccgccagc cgctaatacg caggctttgg cggtaatacg
     5341 ttcgctaccc gccagcgccg ccacgaattc gccgtcatga agttcaagcg cgtgaaccgg
     5401 cgtgttatag cgaatctgta cgcccagccg ttcggcgcta cggtaatagg cattgacgag
     5461 cgctttcccg ccgcccataa aaaacgcatt ggtgcgcgca acgtggagcg ccccagatag
     5521 tggcggttga aagttaacgc catgtttgcg catccagtcg cggcattgcg aagaggtgcg
     5581 aatgaccagc cgcgccagcg cctcgttggt gttgccgtcg gtgactcgcc acagatcctg
     5641 ccagaattcc tcttcaggat agctttccac cagcacatcc tgcggcgcat catgcataca
     5701 gcgcaggttt cgtgtgtgct gagaatttcc gccgcgccat tctcgcgggg cagcctccag
     5761 cagcagaacc gatgcgcccg cttcccgtgc ggtcagggcg gcgcataatg cggcattgcc
     5821 tccgcctatc accagtacat caaccatctt atactcccgt accatttaac tatttgttaa
     5881 atttgtaatt gaaatgtata cggataaata agcggcgcgc tatcaggtag cgctaaacag
     5941 gggtttagta agcgtaaagg gttgcgcctg gccattcacc ggcgtcgact aactgacgca
     6001 taactttggt aaggactact ctggcggcaa ggccggcggg cgtcagttca tcatccgaca
     6061 ggctgactaa aaaattgggg cggctgagta ccggattatg gacgccgatc acgcgtagcg
     6121 cgtcgttatc cagatgagaa atcgccgcgc cgggctgcaa cgtggcgcca agaccgtcgc
     6181 gcacggcgcg catcaacaac gccaggccgt caatttccgc gacgatttca acattaagcg
     6241 catgttcctt gcagacagcg tccagcctgc cgcgcagccc atgtccctgg cttggcataa
     6301 tgagcggaat gcctgccagt tgttcaggtg tgatcgggtt atcaggaagc gccgccagca
     6361 gggcatggga gccaatcaga aaaagctgtt cttcaaggat cggtctggcg ctccagcgca
     6421 ggattttatc tttttgaaag acaacggcta aatcaatctg gcgggtattg atcattcttt
     6481 ccagattacc ggacaagctt tccaccacat gcagtcggac atcggcatag ttttcctgca
     6541 tggcatggat aaacggtata cccagtatgg aggcggtact gggggccatt cctacgctca
     6601 catgaccgga aaggcgcgct tctctggcgg cgagaatcgc gtcgtcggca tgacgcaggg
     6661 cgagttgcgc ctgtgaataa aaggccagcc cggcgttggt tggcgttacg ccgcgcgagg
     6721 tgcgctgcag cagacggatg gcgagctcgt tttccagacg ggacatctgt tgactcaatg
     6781 ctgaaacgcc aatatcaaga tcctgtgcgg cgctgcccat actgccggtt tcaataatac
     6841 gcacgaaata gcgtaactgg cgaagctcca ttcctgctct cctgagatgc gatagcgttt
     6901 tttacattaa atcaacatca agcggcagga aagaggagga tataaaaaag ccaaccgggc
     6961 ggttggctct tcgaaagatt tacacttatt tagtcgcgtc atcgtgcgcg tgctcgtctt
     7021 cgcggcagtc gccttcagcg cagtggccgt aaagatagag gctgtgatta gttaaacgaa
     7081 taccgtgttt cgccgcaatt tcacgctggc gcgcttcaat agagtcatca ctaaattcaa
     7141 tcacttttcc gcagtcaagg cagataagat ggtcgtgatg atgctgttgc gtcagttcaa
     7201 aaacggattt accgccttca aagttatggc gggtcacgat accggcatcg tcaaactggt
     7261 tcagcacacg gtatacggtt gccagaccga tttcttcacc catgtcgatc aggcgtttgt
     7321 ataaatcttc cgcactgacg tgatggttat ctggttcctg aagaacttcc agaattttta
     7381 aacgaggaag cgttactttc aggccagcct tctttaatgc ggtattgttg tcagtcatgc
     7441 ggaatctgtc ctgttgctaa acgattcact tcattagaga agtgacagaa attgcactca
     7501 agataatgcg tatcattata ggactgccat gccgaaatga aaaccgcaag tctctcgcag
     7561 atgttaataa aactgtggtt ttgcctgcaa attctggcgc cacctgatta cacccggaca
     7621 ttgtacaggg atgggtgcga aagttacaaa tttgtagcaa ttattttgat tggtcttgtc
     7681 tattgatgcg gcgcagatat aacgctgcgc cgcataagat taggcgttga ggatgtcgcc
     7741 gaggtgcaat tcagccgaaa cttgcttaac ccatttttca acacgctcgg cggtcagttc
     7801 aggctgacgg tcttcgtcaa tcgccaggcc gacaaaatga tcgtcgtcag ccagaccttt
     7861 agaggcttca aaatgatagc ctgcggttgg ccagtgaccc acaatcgtgg cgccgcgcgg
     7921 ctcaataatg tcgcgaatcg tgcccagcgc atcacagaag tattccgcgt agtcttcctg
     7981 atcgccacag ccaaacagcg ccaccagctt accgttaaag tcaatctctt cgagagtcgg
     8041 gaagaagtca tcccagtcac attgcgcttc gccatagtac caggttggga tgcccagcag
     8101 cagaatgtca tacccttcta ggtcttcttt actgcttttt gcaatgtcat gcacatcggc
     8161 aacgtcttta ccaagctgtt tttgaatcat ttttgcgata ttttcggtat taccggtgtc
     8221 gctgccgaaa aagatgccag tgattgccat gagtaaaata acctcttgaa acttattgaa
     8281 atggtggtgg cgaattgccc acggataagg gcaatcatag cagaacaggc agatatgcgg
     8341 aaacagcaat cacgcgggac tgcacgctct gctacacgaa atatgaaaca aaacttattt
     8401 tcagactaaa ccctggccgc gcagcgccat aagctgcttc attaatattt cttcaatgag
     8461 ctcgctgcgg ctaatgttgc gcgcttcggc cagctcattc agcgcgtcaa ccgcttgtgc
     8521 gttgagtttt aattcgacac gcttgaggcc acgaactttg tcgcgtttta actggttgcg
     8581 cttgttgatg cgtaactgtt catcgcgcga aagcggattc gttttaggtc gtcccgggcg
     8641 acgctcgtgc gcgaacagat ctaatgtcgt acggtccgtt tgttctttgg ccatgatttt
     8701 ggtgacttcg ggggaaacaa tcagccaggc ttatgcccgg atggatagcg cgccatcata
     8761 catcagcgag gaagcgacgc caacgctcgc gcgcgtaatc gcgcacaggc gatgagtttt
     8821 taatcagtta gcgtttatcg tgcagataac ggcggatggc gcgcagaacc gcctctggtt
     8881 tttcggcatg tacccagtgg cccgcgccgg cgatcacatg cgcgcgcgcc aaagggaatt
     8941 gcgccagcag cgcgtcgcgg tacgcttcgg tcacgtacgg cgagttaccg cctggaataa
     9001 acagcgccgg atgttcccag ggcggaatgg tttcccagcc gacgatatgc ggatactgct
     9061 cccataatac cggaacatta aaacgccatt cgccttcagc ccaggatttt aacagaaact
     9121 ggatcacgcc ttctttgttg aggtgctggc gcataatccc tgccgcctgt tggcgggatg
     9181 tcgcgtcgga ttcgctgacg gcgttaatgg ccgcgaaaat gcgatcgtgg cggcgaacgt
     9241 gataatccac gggggcgata tcaatcgcga ccagacgatc gatgcgatcg ggcgccagcg
     9301 ccgtcagcgc cattaccgct tttccaccca tggaatgacc aataaacgtc gctttttcaa
     9361 tctgctgcgc gtcaagcgta tccagaagat cctgggccat tgccggataa tccatgaccg
     9421 gatcgcgcgg cgataaacca tgattgcgca tatcgacctg aataatgtcg tgatcggtca
     9481 ccagatcgcg cgccagtacg ccgaggttgt ccaggctgcc aaacaggcca tgaacgagaa
     9541 cgatggggga attattgtgc aggttttgtg cagattgcgc tcggatgttt aatttcatgg
     9601 caaagttctt tttttcgctc tgtcgggtta gggtattatg ttgaccattc tgccactggg
     9661 ctgcaacctc taaggtttac tccgagtttt tttgtcagcc gggcttaacg ctatccgctg
     9721 ttgggatttg ttcctataat cccaatgact tgtattcagc aaagacatcg cactggatta
     9781 agatgaaaac gattgaagtt gatgatgaac tctatagcta tattgccagc cacaccaagc
     9841 atatcggcga gagcgcatcc gacattttac ggcgtatgtt gaagttttcc gccacgacac
     9901 agccaacggc ttcagcggtg aaggggacgc ctgcggcgca acccgttgcc gaagcgaaac
     9961 cggttaaccc ggtaaaagac aaagttcgcg cgatgcgtga gctgttgttg tctgatgaat
    10021 atgccgagca gaaaaaagcg gtcaaccgct ttatgctgat tctgactaca ctctattcac
    10081 tggatcacca cgcgtttgcg gaggcgacgg agtcgttgca tggccgcacg cgcgtctatt
    10141 ttgcggcgga tgaacaaacg ctgctgaaaa atgggaatca aactaaacct aagcacgttc
    10201 ccggcacgcc gtactgggtg atcaccaaca ccaacaccgg ccgtaaatgc agcatgatcg
    10261 aacacatcat gcagtcaatg caattcccgg cggaattgat tgaaaaggtt tgcggaacaa
    10321 tttaatcctt gcattagaag gaccaggcaa tggcaatcca caaccgcgca ggacaacccg
    10381 cgcaacagag tgatttgatt aacgtcgccc aactgacagc gcagtattat gtactgaaac
    10441 cggaggcagg gaatgcagaa catgccgtga aatttggcac ttccggccat cgcggcagcg
    10501 caggtcgtca cagtttcaac gaaccgcata ttctggcgat cgcccaggcg attgctgaag
    10561 agcgggcgaa aaatggcatt accggcccct gctatgtggg gaaagacacc catgcgctct
    10621 cggaaccggc cttcatttcc gtgctggaag tgctggcggc aaacggcgta gacgttatcg
    10681 tgcaggaaaa taatggcttc acgccaacgc ctgccgtgtc aaatgctatc ctggtccata
    10741 acaaaaaagg cggcccgctg gcagatggta ttgtcattac accgtcgcac aacccgccgg
    10801 aagatggcgg tattaaatat aatccgccca atggcggccc ggcggatacc aacgtcacta
    10861 aagtggtaga agatcgcgcc aatgcgctgc tggcggatgg cctgcaaggc gttaagcgca
    10921 tctctctgga tgcggcaatg gcctcgggtc acgttaaagc ggtagatctg gtacagccgt
    10981 ttgtcgaagg gctggcggat atcgttgata tggcggcgat tcagaaagcc ggtctgacgc
    11041 tgggcgttga tccgctgggc ggctctggta ttgaatactg gaaacgtatc gctgagcatt
    11101 acaagcttaa cctgacgtta gtcaacgatc aggttgatca aaccttccgc tttatgcacc
    11161 ttgataaaga tggcgcgatc cgcatggatt gctcctccga atgtgcgatg gcgggtttgc
    11221 tggcgctgcg tgacaagttt gacctggcct tcgccaacga cccggactac gaccgtcatg
    11281 gcatcgtgac gcctgcaggg ctgatgaacc cgaaccatta tctggcggtc gccattaact
    11341 atctgttcca gcatcgtccg ctgtggggca aagacgtggc tgtcggtaaa acgctggtct
    11401 cttccgcgat gattgaccgc gtggtgaatg atttgggacg caagctggta gaagtgccgg
    11461 ttggcttcaa atggtttgtt gacggtttgt tcgacggcag ctttggtttc ggcggggaag
    11521 agagcgcggg cgcttcgttc ctgcgtttcg acggtacgcc gtggtctacc gataaagacg
    11581 ggatcatcat gtgcctgctg gcggcggaaa tcaccgccgt taccgggaaa aacccgcaag
    11641 agcattacaa tgaactggca gcgcgttttg gcgcgccgag ctataaccgt ctgcaggcgg
    11701 cagcgacctc ggcccagaaa gcggcattgt ctaaactgtc tccggaaatg gtgagcgcca
    11761 gcacgctggc aggcgacccg attaccgcgc gtcttaccgc agcgccgggt aatggcgcat
    11821 cgattggcgg cctgaaggta atgaccgaca acggctggtt cgccgcgcgt ccatccggta
    11881 cggaagacgc ttacaagatc tattgcgaaa gcttcctggg ggaagaacat cgcaagcaga
    11941 ttgagaaaga agccgttgaa atcgttagcg aagtattgaa aaacgcctga tgggcgatat
    12001 ggaagaaaaa ggagccttac ggctcctttt ttgtattaac ggcgctgcgc ttatcaggcc
    12061 tgtaaaccgc ctccaggccg gataaggcgc ttgtgatatc tgacttattc gctctgagtc
    12121 gccagatgtc ggcggcaggt gagggcgtcg cattcgatac gcaccacgca aaccgctttc
    12181 atcatatctt cccgataact gaaggttttt cccggatcgg tctggcgcat aatgacgtcc
    12241 aggccgtggc gcatctcctc gcgcgtttgc aatatcgatg ccagtccggt ggcgaaaacg
    12301 ctggtgtagg cgtagctata atcacagggg tcatcggcac gtagtaatgc atggtcgccg
    12361 tccatttcaa tgcatactgc cgggttctta cgtaacagac gcatcttttt cccggtgcgt
    12421 gcgccgtgaa aataaaatat ccagcgtccg ttctgatact cgtagccaaa atttacgggg
    12481 acaacatacg gacagagatt gtcgttaaac cctatccgac acacttcgtg tttactgaga
    12541 atagccagta tttctgctat atcagtgact tcccgttctg gattactcat ttctattatc
    12601 ttattcaaag agtgaaaatg cccgggctat cgttaccgca gcccgggcgc gccatcagcc
    12661 gtgtttattt ttcaattcaa aacgcggtga gaccaggccg tataacgtcc agccgaggaa
    12721 ggtcacaatt gagccgtaca gcatggcttc ttcaccggag gaatatagcg cgtagaagct
    12781 atacatggcg ccaacgaagg ccacgaagtt agcgactttc gcttttgatg atggcacatt
    12841 cgccattttc tgaatgataa ccagcgcggc catcgacaga atatacggaa taatgttcgt
    12901 caccaccgcc aggttaacca ggacgttaaa ctgactattc agcgacgggc taatggtcat
    12961 cagcgacagg ccagtctgaa taatcacaat aatcagcatc ccctgtaccg gcgcgtcgac
    13021 tttcgttaca cgagagaaga ctttcgggaa atagccttcg tcagcggagg atttaaagac
    13081 ctgggcgata gtgaactgcc agcccagcag cgagccgcag caggacatta ccatcagcgc
    13141 catgatcact ttacctaccg caggcgtgaa catctgtgca aacgccagac caaacggcgc
    13201 cgtggagttc gccagatcca tgttcggcac aatcccggca atcacgttag tcgaaacgat
    13261 atagatgacc gccgcgccca gcgtaccgcc cagtaccgcg atggggacgt tcttttccgg
    13321 attctcgacc acgtctgcgt tagcgcaggc ggattccagt ccaagaaatg cccacaacgt
    13381 catggcgatg gaagagccga ccgcgctaaa gaacggaaca tggtgcgggt tccatgacgc
    13441 tacgtacatg ctggggctaa accagaacca gccaatgatg cacaggccga caaccggaat
    13501 gatgacgccc caaacggtaa cgctactgat ctgtccggta atacgcgcgc cgccaaagtt
    13561 tgcgatggta caaacccaca atacggcgat agtcgccaga ccgatctgga gcggcgtcag
    13621 cgcggcgccg aacagttcgg taccatagcc gacagcggag atggcgatag ccacgttggc
    13681 gatcagcagc gagacgccgt aggtatagtt cgccataaag ttgccggatt taccgaaggc
    13741 atattcggcg taaccgccca tgccgccgga tttacggcta aacataccgc atttcgcaaa
    13801 cgcccaggcc agcgccatcg agccgacggc ggtgaccagc caggagataa tggatatcgt
    13861 gccgacttca gacagtttgg tcggtagcat gatgatcccg gagcccatca tgttgaccat
    13921 agtcagaatt gtgagctgca cgacacccat tttattggat ttaggtttac tcataatttt
    13981 tcctccttca gcagggagcg ctgcgcgtca cgaggtttaa tgacgtagca ccagacctgc
    14041 ttacggccgt cgtgttcttc gatataaacg ccctgcagtt caggcgcaaa gcccggcagc
    14101 aggttgatcc cttcttccag ggcgctgaag taacgcagga cagaaccgcc ccagatttca
    14161 cccggaacta cacacagcac tcccggcggg taaggcagag cgccttcagc cgcgatacga
    14221 ccttccgctt ccggcaggcg aaccagttcg acctcgccgc gcagataggc atagttggcc
    14281 tcttgcgggt tcatactgac tttcgggaaa tgcgatttac ggaacatctc tttttgcagc
    14341 tgtttcacgt tgtgccgcgc atagagatcg tgcatctcct ggcaaagctg acgcagggta
    14401 tagccggcat aacgcgcttc atgctgtttg tagatggacg gtaatacttc cgctaacggc
    14461 gcatcagctt ccagcagttt ttcgaaacga gccagcagag cgacaagctg ttgtaacttc
    14521 gccatgtctt ctgccggcgt cagcaggaac agaatggagt tgaggtcgca tttttccggc
    14581 acaacgccgt tctcgcgcag gaagttggcg aggatcgtgg caggaacgcc aaagtcttca
    14641 tattcgccgc tcgctgcatt aatgcccggt gtggtgagca gcagtttgca agggtcgaca
    14701 aagtactgat gttcggcata gccttcaaac gcatgccagt gttctcccgg aacgaagtgg
    14761 aagaagcgca gatcgctggc gatctctgac gttgggtatg actgccacgg cttaccatca
    14821 atcagttccg gtacgaacgg acggatgtgg tgacagtttt cgaggatcaa tttacgggca
    14881 tcgatgccgt taactacgca atccatccac atattgcgac cgctgacgcc ttcgtgcatt
    14941 ttggcgttaa cgtccagcgc ggcgaacagc ggatagaacg ggctggtgga ggcgtgcatc
    15001 ataaaggcgt tgttcatgcg cttatgcgga acgtagcgcg attgcccttt gatatggcta
    15061 tcttttttat ggatctgcga ggtctgggag aaaccggctt gttgtttgtg aacggactgc
    15121 gtcaccagaa tacccggatc gttttcgttc agttccagca gcagcggcga acaatcggcc
    15181 atcatcggaa taaattgttc atagccgacc caggcggagt caaacaggat gtagtcgcac
    15241 agatgaccaa ttttatcgac gacctgacag gcgttataaa tggtaccgtc gtaggtgcct
    15301 aagtaccgtc gtaggtgcct aactggatga cggccagacg gaatggacgt gcttcgtggg
    15361 cacgctgcgg cgcgacttcg ctaatcagct cgcgcaggta atcttcttcg aagcagtgag
    15421 cgtcgatccc gccgataaaa ccatacggtt acgcgcggtt tccagataaa ctggcgttgc
    15481 gcccgcctgc aataatgcgc cgtggtggtt agatttgtgg ttgttacggt caaacagtac
    15541 cagatcgccc ggcgttaaca gcgcgttgag tacgactttg ttagaggagg aggtcccgtt
    15601 cagcacaaag taggtcttat cggcgttaaa gactttcgcc gccctgatgc cccgggcagt
    15661 caaatgcgct gttgccctgg ttgacataat ccaccagcgc gcggaaaaac ggcggacgta
    15721 actgcgtttc gtagtggctt gctgcggttt ccaactggcg accatagaag gcagtacggg
    15781 attcattata ttcgaataca ccagagatac gcggcaaata ctcaggcggt acgcgtcctt
    15841 cgtcatgagt cgcgacaaac acgggaatac cgtaacccgt tgcgtcgatt tcatcgagtt
    15901 ttccgtgttc aatgtcgtcg atggataaca cggatgcagc cacgtcgatg aaacgactct
    15961 catcaacatt tacaatatta cggtgtgtag aaaaacaatc cgggcaatga cggctaacgg
    16021 caatttttaa ttctgacatt tttcatctct ttatttcagg taatagcagg ccctcaattt
    16081 ctcgcatgag aaactgattc ttccggaaaa aatcaaagct atcccgctga taaaaaaatc
    16141 agtaaattag ctttatttta gatgtaataa atcccaaccc gtccggttgc aggaaattca
    16201 ggatttaagg agttgagtac tacgatatac aggcagaaac cgcgataact aaaattgcgc
    16261 tgagtcggaa tttcttctgt caaaccacat agttagctgg ctgggcgtaa aggaattacc
    16321 gtactgtcgc ttttaacaat tcgagttatt taggcaatag acctgaatga cataagggtc
    16381 ggaaagacct gtatgctgaa gtacccgtag cagaaaaaat accgggcatt aaagaaatga
    16441 aagtcgaaac tattacggtg ggcaaacatc ataatatgcg ttgtccgcct tatatggggc
    16501 ataaaacgat tattattttc cattttgagg tcctttcatt gatttattga aagcatggat
    16561 attttatcca gggagcgcca gcaatctgtg aaccagatca acaaaaaacg atcatttgaa
    16621 aaataattag tcggcg
//
LOCUS       DAJVBX010000095        16440 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.095, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000095 DAJVBX010000000
VERSION     DAJVBX010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 16440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16440
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.095"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(5..1405)
                     /locus_tag="OPV72_002589"
     CDS             complement(5..1405)
                     /locus_tag="OPV72_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome-c peroxidase"
                     /protein_id="HCR9914849.1"
                     /translation="MKKITLYATTVITVGLLCYLGLSGYVWYYDKQRSKKSDVQASVV
                     GENNKILGYFREKGCDYCHTPSAELPFYSSFPVAKQLMDYDIQLGYKSFNLEAVRAAL
                     IADTPVPQSELNKIEWVMQHQTMPPTRYVALHWAGGVSDKERTDILNWIADQRERNYA
                     SADTDPAHRNEPVQPIPRNIPVDAKKVDLGFRLYHDERLSGDSTISCAHCHALNAGGV
                     DGRKTSIGVGGAVGPINAPTVFNSVFNIEQFWDGRAATLQEQAGGPPLNPIEMASKSW
                     DEIISKLDKDPVLKKDFQAVYPQGFTGENITDAIAEFEKTLITPDSAFDKWLRGDENA
                     LTAQQKHGYQLFKENKCATCHGGIILGGRSFEPLGLKRDFNFGEITAADIGRMNVTKE
                     VRDKLRQKVPGLRNVALTAPYFHRGDVPTLDGAVKLMLRYQVGTDLPQNDIDDIVAFL
                     ESLTGVYTPYQPEYAQ"
     gene            complement(1595..2227)
                     /gene="torD"
                     /locus_tag="OPV72_002590"
     CDS             complement(1595..2227)
                     /gene="torD"
                     /locus_tag="OPV72_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone TorD"
                     /protein_id="HCR9914850.1"
                     /translation="MIKQPALAQEQYACVYAWLALLFFREVDDEGLIQLQSAEIADWL
                     ALLKRQPALAASVALLEQKIAALSLRQDAQLELAADFCGLFLMTDKKSALPYASQYPQ
                     QEPGMIKHLLLEAGMEVNDDFKEPADHLAIYLELLSHLHFSLGESFQQRRMNKLRQKT
                     LSSLLEWLPEFTNNCLKHDPYGFYAALSQLLLAIVRFDDGKEDLSIVAVE"
     gene            complement(2220..4772)
                     /gene="torA"
                     /locus_tag="OPV72_002591"
     CDS             complement(2220..4772)
                     /gene="torA"
                     /locus_tag="OPV72_002591"
                     /EC_number="1.7.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethylamine-N-oxide reductase TorA"
                     /protein_id="HCR9914851.1"
                     /translation="MKNKDSLHVSRRRFLAQLGGLTVAGMLGPSLLTPRSARAADAVA
                     PGAATKEGILTGSHWGAIRATVVDGRFVAAKPFEQDKYPSKMIAGLPDHVHNAARIRY
                     PMVRVDWMRKGHQSDTSQRGDNRFVRVSWDEALDLFYQELERVQKTYGPSALLTASGW
                     QSTGMFHNASGMLARAIALHGNSVSTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLV
                     LQNSKTIVLWGSDMVKNQQANWWCPDHDVYQYYEQLKEKVASGAISVISIDPVVTSTH
                     DYLGRDKVKHIAINPQTDVPLQLALAHTLYSEKLYDKNFLDNYCVGFDQFLPYLLGEK
                     DGQPKDAAWAEKLCGIDADTIRALARQMAGDRTQIIAGWCVQRMQHGEQWSWMVVVLA
                     AMLGQIGLPGGGFGFGWHYNGAGTPGRKGIILSGFSGSTTVPPVHDSTDYKGYSSTIP
                     IARFMDAILEPGKIINWNGKSVKLPPLKMCVFAGTNPFHRHQQINRIIEGWRKLETVI
                     AIDNQWTSTCRFADIVLPATTQFERNDLDQFGNHSNRGIIAMKQVVSPQFEARNDFDI
                     FRDLCRRFNREAAFTEGLDEMGWLKRIWQEGSQQGKGRGIHLPTFEVFWNQQEYIEFD
                     HPQMFVRHQAFREDPDLEPLGTPSGLIEIYSKTIADMQYDDCQGHPMWFEKIERSHGG
                     PGSQRWPLHLQSVHPDFRLHSQLCESETLRQQYAVGGKEPVFINPQDASARGIRNGDI
                     VRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGDLNALCKYGNPNVLTLDTG
                     TSQLAQATSAHTTLVEIEKYTGPMDNVTAFNGPAEMVAQCEYVPASQGNPHD"
     gene            complement(4762..5946)
                     /gene="torC"
                     /locus_tag="OPV72_002592"
     CDS             complement(4762..5946)
                     /gene="torC"
                     /locus_tag="OPV72_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentaheme c-type cytochrome TorC"
                     /protein_id="HCR9914852.1"
                     /translation="MRKLWRALLRPSTRWSILALVIVGIVIGVALIVLPHVGIKLTST
                     TEFCVSCHSVQPVYQEYKQSVHFQNASGVRAECHDCHIPPDIPGMVKRKLEASNDLYQ
                     TFIAHSIDTPEKFEAKRAELAEREWARMKENNSATCRSCHNYDAMDHAKQNPEAARQM
                     KIAAKENQSCIDCHKGIAHQLPDMSSGFRKQFDELRASASTHNDGDTLYSLDIKPIYA
                     AKGDKEPAGSLLPASEVKVLKRDGDWLQVQIEGWTETDGRQRVLTQLPGKRIFVASIR
                     GDVQQHVKTLEETTVAATNTQWSKLQATAWMQKGDMVNDIKPIWAYADSLYNGTCNQC
                     HGAPDKAHFDANGWIGTLNGMIGFTSLDKRDERTLLKYLQMNASDTTNTPHSDKGEHN
                     EK"
     gene            6076..6770
                     /gene="torR"
                     /locus_tag="OPV72_002593"
                     /pseudo
     CDS             6076..6770
                     /gene="torR"
                     /locus_tag="OPV72_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462724.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator TorR"
     gene            complement(6743..7783)
                     /gene="torT"
                     /locus_tag="OPV72_002594"
     CDS             complement(6743..7783)
                     /gene="torT"
                     /locus_tag="OPV72_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TMAO reductase system periplasmic protein TorT"
                     /protein_id="HCR9914853.1"
                     /translation="MRTLISFFFLIIIVSNVETASAETGLLHWTRADRAIPWRQTSVN
                     ASKPWKLCALYPSLKDSYWLSVNYGMQKAAKLYGVDLKVLEANGYRQLATQQQQMTQC
                     REWGADAILLGSSTDRFPELERYAGNVPVIELVNMIHDASVATRIGLPWFQMGYLPGR
                     FLVQWSKGKTLNVLLFPGPEEAGGSQEMVAGFRQAIKGSAINIVDIAWGDNDIEVQRN
                     LLQEMLERHPDANVVAGSAIAAEAAMGEGRNLTTPLTIVSFYLTHQVYRGLKRGHILM
                     ALSDQMAWQGELAITQSIKVLQGQPVPENISPPVLILTHNNADSARVRRSLSPPGFRP
                     VYLYQYTSEAKK"
     gene            7863..10598
                     /gene="torS"
                     /locus_tag="OPV72_002595"
     CDS             7863..10598
                     /gene="torS"
                     /locus_tag="OPV72_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TMAO reductase system sensor histidine
                     kinase/response regulator TorS"
                     /protein_id="HCR9914854.1"
                     /translation="MSTPSLTHRLWLAFALMAALTLLSTVIGWISLRVISQVEQTNTQ
                     ALLPTMNMARQLSEASAYELFSAQNLTNADSEGVWLAQGKMLKAQSLKINHLLQALSE
                     QGFNTSAIARQEKEIAQTLGQQGTLVGEILTLRAQQQQLSRQIAEAAESIAAQAHGQA
                     NNAATSAGATQAGIYDLIESGKGDQAERALDRLIDIDLEYVNQMNELRVNALRFKQLI
                     VTLKDAQGLSDAEETDEKLNQLVKILSRRQQRIEDPTVRAQIADALGKINQYTTLVTL
                     FRKENAIRDQLQTLMANNLFQFTRFSTEVSQLVNAIEKRNEAGLARLTHASQRGQIGL
                     VILGILALCSLSFILWRVVYRSVSRPLAQQTQALQRLLEGDIDSPFPEAAGVSELDTI
                     SRLMEAFRANVRKLNRHREDLAEQVRSQTAELHALVLEHRQARAEAEKANEAKSTFLA
                     AMSHEIRTPLYGILGTVQLLADKPLMANYRDDLQAINDSGESLLAILNDILDYSAIEV
                     GGTNVSISEEPFEPRQLLNSALHLMHSRVQVALITDFSEQLPSTLQGDPRRIRQIVIN
                     LLSNAAKFTDRGSIVLRTFCDDQSWFIEVEDTGCGIPEAKLTAIFKPFVQATGCRGGT
                     GLGLAISASLAEAMGGTLTVTSTLHVGSCFRLQLPVRHPKPASKSAFREPVNLNGLRL
                     LLIEDNMLTQRITAEMLTGKGVKVSVAESANDALRCLAEGEPFDVALVDFDLPDYDGL
                     TLAQQLMSLYPAMKRIGFSAHVIDDNLRQRTAGLFCGIIQKPVPREELYRMIAHYLQG
                     KSHNARVMLNEHQLAGDMASVGPEKLRQWVALFKDSALPLVEEIEAARAMNDDVNIKR
                     LAHKLKSGCASLGMTQATEACRELELQPLSDIDIKTIVTQGVTALDAWIAGHPSP"
     gene            complement(10703..11830)
                     /locus_tag="OPV72_002596"
     CDS             complement(10703..11830)
                     /locus_tag="OPV72_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006762570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4056 domain-containing protein"
                     /protein_id="HCR9914855.1"
                     /translation="MRTIVRVIFLALLFLAGSARAALPLTLYLSTLPMPAASEAWPTM
                     PPQPLPKGLRPCCAFGYDLHAELLGLPVPFYQLNNVVTVDSLGHHQYNDHLYSGVANL
                     IGLSGENNGIVYTLRGGFIDTAHVRDTADMTVYIFSQLLPKLGQAFTLNLGEELAERR
                     LVFTAFTPPVDARERYTLAAWLSAHLAFQVAEWHEIAQWYGFESVRGFSEGVSAFSPE
                     DLYSNLAGARLAASLIVDGQTKTQEMYNTAMETALRQALTQLAAQPAQITRFQFDMLD
                     GRWWNSQRRVPEKYLVLHRNYQMGDDRLPTAVPGEITSLLPLSLPHRWRGIQLSTLAQ
                     LQLWPSEDMAQLPPPAHYYSEKDFAALAEQARLQDEKTQNH"
     gene            complement(11827..12966)
                     /locus_tag="OPV72_002597"
     CDS             complement(11827..12966)
                     /locus_tag="OPV72_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001528293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BamA/TamA family outer membrane protein"
                     /protein_id="HCR9914856.1"
                     /translation="MNRCHCRQLLCVAGVLSGVAQAALPSRSQVDGWLQQMGDSDTYD
                     AAKGVNWGVMPGPFYTPELGLGIGTAIVGMYRPDPADKVSQISTLSLSGYFSSTGAFG
                     VSLQNYAFFAQDRWRFFLTGALSDTPTYYWGQGFAAGDKDSHKQAYTAQVLDLQPMLY
                     RRLVNNIYLGVGWTLDVQHAAQINEDDPPRIQHTAQGGSSLSNGGSVEISWDDRDFMP
                     NPRKGQYATLRYTHFAPDIGSDTRFDEYQLHYSQYHAVDDKDVLAWEADGAFTQGYVP
                     WNMLPLLGSNHRMRGYYEGRYRDKNAVSGQLEYRHKLSWRHGVVGWVGAGTMGSSLHH
                     LDDGRWLPSAGVGYRFEFKPRVNVRLDYGVGKGSSGFYFQVGEAF"
     gene            complement(12963..13985)
                     /locus_tag="OPV72_002598"
     CDS             complement(12963..13985)
                     /locus_tag="OPV72_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001528257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914857.1"
                     /translation="MKKRSLLLLALPAMAFSTWAATSPPANLSPVYSYQDDVPSAATP
                     PVATTPVAKPASTSVLPFLGDEARKRGYELPEPFGLNINYMNIGQNINVDSINFNGLA
                     LGPNGGIPLDNAFKINVGHTREKSKTETVKLDAWLLPFMNVYGLVGYTDGHSVSQIGV
                     GLMTKNGHVFHPADLQNLKFKLDFKGTTYGIGTTLVGGVGNWFTAVDANYTQTQFDIL
                     DGSIDAFTVSPRVGYRFTTPGIDKMHLPSGKLNVWVGSMYQDVQQEFKGSLDDLTMPS
                     ATLQRLVSMANYNNNGRFDVKQHLQSPWNMLLGAQYEITRHFNVTTEFGFAERNSFFV
                     AGEYRF"
     gene            complement(14187..14999)
                     /gene="yidA"
                     /locus_tag="OPV72_002599"
     CDS             complement(14187..14999)
                     /gene="yidA"
                     /locus_tag="OPV72_002599"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HCR9914858.1"
                     /translation="MAIKLIAIDMDGTLLLPDHTISPAVKNAIAAAREKGVNVVLTTG
                     RPYAGVHSYLKELHMEQPGDYCITYNGALVQKAGDGSTVAQTALSYDDYRYLEKLSRE
                     VGSHFHALDRNTLYTANRDISYYTVHESYVATIPLVFCEAEKMDPNTQFLKVMMIDEP
                     AVLDRAIARIPAEVKEKYTVLKSAPYFLEILDKRVNKGTGVKSLAEALGIKPEEVMAI
                     GDQENDIAMIEYAGMGVAMDNAIPSVKEVANFVTKSNLEDGVAWAIEQHVLS"
     gene            15288..>16440
                     /locus_tag="OPV72_002600"
     CDS             15288..>16440
                     /locus_tag="OPV72_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR9914859.1"
                     /translation="MSMALTAPPGRKRFLIVACLFIGIFIAYLDRVNVSVLAANEPFL
                     AYMGIEGMPLQIGMMMTVFLAAYGIANVVLSPLGDYLGPRKAMMLCILIWTIALIIGG
                     VATSFALIIICRILLGIGEGFYYPLQSVFIKNWFPKQERGRANAAWIVGQSVAPAIAM
                     PFFTWWIGTHGWRSNFFLCAALGLIPLWLLWRYVADKPEQHKSISEQELAYIKAGQET
                     ESASSSESFMLRVKPVITNYCYWLLVLWYLCLQCLYWGMITWLPTYLKSARGFSWAEM
                     GWLASLPFVLSIFSKAAAGVFVDKIGRSAPILMVLMFFAGISIYFGTITEHKYMSAVL
                     LSFAVAFCTMGTPVAWTLLQGMVSGKSISAASGVMNGVANGLSSLSPVFI"
BASE COUNT         3845 a         4433 c         4255 g         3907 t
ORIGIN      
        1 attgtcattg cgcatattca ggttgatatg gcgtataaac accggtcagg ctttccagga
       61 aggcgacgat atcgtcaata tcgttttgcg gcagatcggt gccaacctgg taacgcagca
      121 tcagttttac cgcgccatcc agcgtcggta cgtcgccccg atggaaataa ggcgctgtta
      181 acgcgacgtt gcgtaagcct gggacttttt gccgtaattt atcgcgaacc tctttggtga
      241 cgttcatacg accaatatcc gctgcggtaa tttcgccaaa attaaagtct cgctttaatc
      301 ccaatggttc aaaagagcgc ccgcctaaaa tgataccgcc gtgacaggtt gcacatttat
      361 tttctttaaa taattgataa ccgtgtttct gttgcgcggt cagcgcattt tcatctccac
      421 gtagccattt atcaaaagcg gaatccggcg ttatcaacgt tttttcgaat tcggcgatcg
      481 catcagtaat attttccccg gtaaatcctt gcggataaac cgcctggaaa tcttttttca
      541 ggacagggtc tttatcaagc ttgctaataa tttcatccca ggatttagag gccatttcaa
      601 taggatttaa cggcggtccg cctgcttgct cctgcagggt tgcagcacga ccatcccaaa
      661 attgttcgat attaaatacg gagttgaata ccgtcggcgc atttattggc cctaccgcac
      721 cgccaacgcc aattgaggtt tttctgccat cgacaccgcc cgcatttaac gcgtgacaat
      781 gcgcacagga tattgtgctg tcgccggata aacgttcatc atgataaagt cggaaaccta
      841 agtcgacttt tttcgcatcg acgggaatat tgcgcggaat aggctgaacg ggttcattcc
      901 ggtgtgcggg gtcggtatcg gcgctggcat agttgcgctc acgctgatcg gctatccagt
      961 tcaggatgtc agtacgctct ttatcgctga cgccccccgc ccagtgcagc gcgacatagc
     1021 gggttggtgg catagtctga tgttgcataa cccattcaat tttattcagt tcgctttgcg
     1081 gcaccggcgt atccgcaatc agggcggccc gtaccgcctc caggttaaac gacttgtagc
     1141 cgagctggat atcgtaatcc attagctgct ttgccaccgg aaaagaggaa taaaaaggca
     1201 attcagcgga aggcgtatga caataatcac atcctttctc cctgaaataa cccagtattt
     1261 tattattttc acccacaacc gaggcctgca catcgctttt tttactgcgc tgtttgtcgt
     1321 aataccatac atacccggac aaacctaaat aacataacag cccaacggtg ataaccgttg
     1381 tcgcatagag ggtaattttt ttcatatcac tatccttatg gggtattgcg gcataattaa
     1441 ttaaatttta tttttttact catgaggccc gtcaatacta aatacaaacc catcatggat
     1501 attgattggt atcaataatt acaattggct aaacctatag atatgataac ccccgactat
     1561 cgtaagattt attttgcgat gcccgtcaca gggtttattc aaccgcaaca atggataaat
     1621 cctcttttcc gtcatcaaaa cgaacgatag ccaacaataa ttgacttaac gcagcataaa
     1681 aaccataggg atcatgctta aggcaattat ttgtaaattc cggaagccac tccagtaatg
     1741 acgataatgt tttctggcgt aatttattca ttctccgttg ttggaacgat tcacccaatg
     1801 aaaaatgtaa atggctgagt aattccagat aaatcgccaa gtggtcggcc ggctctttaa
     1861 aatcgtcgtt gacttccatc ccggcttcaa gcaataaatg tttaatcatg ccgggttcct
     1921 gctgcgggta ttgcgaggcg tagggcaagg ccgatttttt atccgtcatc aggaacaatc
     1981 cgcaaaaatc cgcggccagc tccagctgcg catcctgacg caggctaagc gcggcaattt
     2041 tttgttcgag taacgccacc gacgccgcca gcgctggctg acgctttaac agcgccagcc
     2101 agtccgcgat ttccgcggac tgtaattgta ttaacccttc atcatccact tcccggaaaa
     2161 agagtaacgc cagccatgca tatacgcagg cgtactgttc ctgagcaagc gctggctgct
     2221 taatcatgcg gattcccctg cgatgcgggt acatattcac actgcgcgac catctcggcc
     2281 ggaccgttaa acgccgtgac gttatccata ggaccggtat atttttcaat ttccaccagc
     2341 gtcgtatgcg cgctggtcgc ctgcgcgagc tgtgatgtac cggtatccag cgttaatacg
     2401 ttagggttgc cgtacttaca taacgcgttg agatcgccgc ctttatcagg atcgtaccag
     2461 gcaccttcat gaattcgcgc cacgcccggc gcatagcgat cggaaactac cgctcccgcc
     2521 agtacctgcc cgcgtgcatt gaatacccgc acgatgtcac cgttgcggat cccgcgcgcg
     2581 ctggcatcct gtgggttaat aaagaccggc tccttgccgc caacggcata ttgctgacgc
     2641 agcgtttccg actcgcacag ttgggaatgc agacggaaat cagggtggac ggactgtaag
     2701 tgcagcggcc agcgctgcga tcccggcccg ccatgcgagc gttcgatttt ttcgaaccac
     2761 atgggatggc cctgacaatc gtcgtattgc atgtcggcga tcgttttgga gtaaatctcg
     2821 atcaaaccgc ttggcgtgcc caacggctcc aggtccggat cttcacggaa agcctgatgg
     2881 cgcacaaaca tctgcggatg atcaaactcg atgtactcct gttgattcca gaacacctcg
     2941 aaagtcggta agtggatacc gcgacctttt ccctgctggc tcccttcctg ccagatgcgt
     3001 ttcagccagc ccatttcatc aagaccttcc gtgaatgccg cttcacggtt aaagcgtcgg
     3061 cagagatcgc ggaaaatatc aaagtcgtta cgcgcttcaa actgcggcga caccacctgt
     3121 ttcatggcga taatgccgcg gttagagtgg ttgccgaact gatcgaggtc gttacgctca
     3181 aattgggtgg tagccggcaa aacgatatcc gcaaagcggc aggtcgacgt ccactggtta
     3241 tcaatagcga tgaccgtttc cagcttgcgc cagccttcaa ttatgcggtt aatttgttgg
     3301 tgtcggtgga acgggttggt cccggcgaac acgcacatct tcagcggcgg taatttaacc
     3361 gatttcccgt tccagttaat gatcttgccc ggttcaagaa tggcatccat aaaacgcgca
     3421 ataggaatgg tgctgctgta gcctttgtaa tccgtgctgt cgtgcactgg cggaacggtc
     3481 gtcgaaccgg aaaagccgct taaaatgatc cctttacgac caggcgtccc ggcgccgtta
     3541 tagtgccagc caaaaccaaa gccgccgccc ggtaaaccaa tctgtcccag cattgccgcc
     3601 agcacgacga ccatccatga ccactgttcg ccatgctgca tacgttgtac gcaccagcca
     3661 gcgatgattt gcgttctgtc gcccgccatc tgccgcgcca acgcgcggat ggtgtcggcg
     3721 tcaataccgc acagtttttc cgcccaggcg gcatctttgg gctgtccatc tttctcgccc
     3781 agcaaatagg ggaggaactg gtcaaaaccg acgcagtagt tatcgaggaa atttttatcg
     3841 tacagtttct cgctgtacag ggtatgcgcc agcgccagtt gtaacgggac atccgtctgc
     3901 gggttaatgg cgatatgttt gaccttatcg cgccccagat aatcgtgcgt ggaggtgacg
     3961 accgggtcga tgctgatgac cgagatagcg ccgctggcaa ccttctcttt taattgttca
     4021 tagtactgat agacatcgtg atccgggcac caccagtttg cctgctggtt tttcaccata
     4081 tcagaacccc atagcacaat cgttttactg ttctgtaaaa ccagaggcca tgacgtttgc
     4141 tgctcgtaca cttccattga acccaccaca cgcggcagaa tcacctgcgc cgcgccggtc
     4201 gaatagtccc ctcccgtgct gacgctattg ccatgtagcg caatcgcgcg cgccagcatc
     4261 ccggaggcgt tatggaacat gccggtagat tgccaaccgc tcgccgtcag taacgcgctc
     4321 ggcccgtagg ttttttgcac ccgctccagt tcctgataga acagatccag cgcttcatcc
     4381 caggagacgc gcacaaaacg attatcgccg cgctgcgagg tgtcgctttg atgacctttg
     4441 cgcatccagt cgacgcgcac catcggatag cgaatacgcg ccgcgttgtg gacgtgatcg
     4501 ggcagaccgg cgatcatttt ggacgggtat ttatcctgtt caaacggttt tgccgccaca
     4561 aatcgaccgt caaccaccgt ggcgcgaatc gccccccagt gagaaccggt aaggataccc
     4621 tctttcgtcg cggcgcctgg cgcaacggca tccgctgcgc gggcgctacg gggcgtcagt
     4681 agtgacggcc ccagcattcc tgccaccgtc aagccgccaa gctgcgccag aaaacgtcga
     4741 cgagagacgt gtaacgagtc cttatttttc attgtgttct cccttatcgc tgtgcggcgt
     4801 gttggtggta tcagacgcat tcatctggag atatttcaac aaggtacgtt catcacgctt
     4861 atccagactg gtgaaaccga tcatgccgtt gagcgtgccg atccagccgt tagcgtcaaa
     4921 gtgcgctttg tccggcgcac cgtgacactg attacaggtg ccgttataga gggagtcggc
     4981 ataggcccaa atcggtttaa tgtcatttac catgtcacct ttttgcatcc acgcggttgc
     5041 ctgtaatttg ctccactgag tattggtcgc cgcgacggtg gtctcttcca gcgttttcac
     5101 atgctgttgc acatcgccgc gaatcgaggc gacaaaaata cgtttaccgg gcaactgcgt
     5161 cagcacgcgc tggcgaccgt ccgtctccgt ccagccttcg atttgcactt gcagccagtc
     5221 accgtcccgt ttaaggactt tcacttcaga agcaggcaac agcgaacctg ccggttcttt
     5281 atcgccttta gcggcgtaaa tcggcttgat atccagcgaa tagagcgtat cgccgtcatt
     5341 atgcgtactg gcgctggcgc gcagttcatc aaactgtttg cggaaaccgc tgctcatatc
     5401 cggtagctgg tgggcaatcc ctttatggca gtcgatgcag gattgatttt ctttcgcggc
     5461 gattttcatt tgccgcgccg cttccgggtt ctgtttcgcg tgatccatcg catcgtagtt
     5521 atggcaggaa cgacaggtcg cggagttatt ctctttcatg cgcgcccatt ctcgctcggc
     5581 aagctcggcg cgtttagctt caaatttttc cggggtatca atcgagtggg cgataaatgt
     5641 ctggtaaaga tcgttgctgg cttccagctt acgtttcacc atgcctggaa tatcgggggg
     5701 gatatggcaa tcgtggcatt ccgcgcgtac gccggaagcg ttctggaaat gtacggactg
     5761 tttatattcc tgatacaccg gctgcacact atggcagctg acgcaaaact ctgtcgtact
     5821 ggtcagtttg ataccgacgt gaggtaacac gatcagcgca acgccgatca caatcccgac
     5881 aatgaccagc gccagtatcg accaacgggt gcttggcctg agtaacgctc tccagagttt
     5941 tcgcataata gcccctgtaa ttatatggtt taatgcgcag atcttattcc gcaaatatga
     6001 acagcgtcac tggtcaggat gaacgggata cggcaatata tgaacagata tgaacagaaa
     6061 gagaccgcgc gcaggatgtc acatcacatt gttattgttg aggatgaacc tgttactcag
     6121 gccaggttac aggcctattt tgagcaggag gggtatcgcg tttcggtgac cgacagcggc
     6181 gcgggcctgc gcgtgacatc atggagcatg agcacgtttc gctgatcctg ctggatatca
     6241 acctccccga tgaaaacggg ttgatgctga ccagggcgct acgcgaacgc tccacggtgg
     6301 gcattattct ggtgacgggg cgttgcgacc aaatcgaccg catcgtcggg ctggagatgg
     6361 gcgcggacga ctacgtcacc aagccgctgg aactgcgcga gctggtagtg cgggtgaaaa
     6421 atcttttgtg gcgtatcgat ctggcccgcc ccacgccgca aaatgccagt gaaaactgct
     6481 atatgttttc cggctactgc ctgaacgtga tgaatcacac gctggagcac aacggtgaag
     6541 ccattaagct tacgcgcgcg gagtacgagc tgctgctggc ctttgtgacc aacccaggca
     6601 aagtgctgca tcgcgaacgt ctgctgcgaa tgctttccgc ccgccgcgta gagaccccgg
     6661 atctccgcac gattgatgtc ctggttcgcc gcttacgtca taaaattacg ccggaactgc
     6721 tggtcacaca gcatggcgaa ggctactttt tagcctcgga ggtgtattga tacagataga
     6781 cgggccgaaa tcccggaggc gatagcgaac ggcgaacgcg cgcgctgtcg gcgttgttat
     6841 gcgtcaaaat aagtaccggc gggctgatat tttcaggcac cggttgcccc tgtaagacct
     6901 taatcgactg cgttatcgct aattctccct gccaggccat ctgatcgctg agcgccatca
     6961 ggatatggcc gcgttttaaa ccgcgataaa cttgatgcgt cagataaaat gagacgatcg
     7021 tgagcggagt cgtcaaattt cgcccttcgc ccatcgccgc ctccgccgct atcgccgacc
     7081 cggcgaccac attggcgtcc ggatggcgtt ccagcatttc ctggagtaag tttcgctgca
     7141 cttcaatgtc gttatcgccc caggcgatat ccacaatgtt gatggcgctg cctttaattg
     7201 cctgacgaaa acccgccacc atctcctgac tgccgccggc ttcttccggc cccgggaaga
     7261 gtaaaacgtt aagcgttttt cctttgctcc actgcaccag gaaacgtccc ggcagataac
     7321 ccatctgaaa ccacggcaga ccaatgcggg ttgcgacgct ggcatcgtga atcatgttca
     7381 ccagttcaat aaccggcaca ttaccggcat atcgttccag ctccgggaaa cgatcggtac
     7441 tgctgccaag cagaatagcg tcggcgcccc actcccggca ctgcgtcatt tgctgttgtt
     7501 gcgtcgccag ttgccgatag ccattcgctt ccagcacttt taaatcaacg ccatacaatt
     7561 tggccgcttt ttgcatcccg tagttgacgg acaaccagta agaatctttc aggctggggt
     7621 ataatgcgca cagtttccag ggtttactcg cattgactga cgtttgccgc cagggaatcg
     7681 cccgatcggc gcgcgtccag tgtagcaacc cggtttcggc tgacgccgtt tctacattcg
     7741 agacgatgat tatcaaaaaa aagaacgaaa taagcgtgcg catgatagcc ccaccagcaa
     7801 caaggtttta tcctaatggt ttttccggcg gcaactcaac ccatttcacc cgcggcgcat
     7861 aaatgtcaac gccttcactg acccacagat tatggctggc cttcgctctg atggcggcac
     7921 tcaccctgct cagcaccgtg atcggctgga taagcctgcg cgtcattagt caggtggagc
     7981 aaaccaatac gcaagcgctg ctccccacga tgaatatggc caggcagtta agcgaagcca
     8041 gcgcttacga gctcttttcc gcgcaaaatc tgaccaatgc cgacagcgag ggcgtttggc
     8101 tggcgcaggg gaagatgctg aaagcgcaaa gccttaaaat taaccatctt ttgcaggcat
     8161 taagcgagca ggggtttaat acctcggcca tcgcccggca agaaaaagag attgcgcaaa
     8221 cgcttgggca gcagggaacg ctggtcggtg aaattctcac gctgcgcgca cagcaacagc
     8281 agttaagccg ccagattgcg gaggcggcgg aaagcattgc cgcccaggct cacggtcaag
     8341 ccaataatgc agcgacatct gcgggcgcca cccaggccgg tatttacgat cttatcgaaa
     8401 gcggtaaagg ggatcaggct gaacgcgcgc ttgaccgact gattgatatc gaccttgagt
     8461 atgtgaatca gatgaatgag ttgcgggtca atgccctgcg gtttaagcag ctcattgtga
     8521 ccttaaaaga cgcgcaaggg ctgagcgatg ccgaggaaac cgatgaaaaa cttaatcagt
     8581 tggttaaaat tttatcccgc cgccagcagc gtatagaaga tcctaccgtt cgcgcccaaa
     8641 tcgccgacgc gctggggaaa ataaaccagt acacgacact ggttaccctg tttcgtaagg
     8701 aaaacgccat ccgcgaccag cttcaaacgc ttatggccaa taacctcttt cagtttaccc
     8761 gcttcagtac ggaagtgtcg cagttggtga acgccatcga aaaacgaaac gaggctgggt
     8821 tagcgcgtct tacacacgcc agtcagcgtg ggcaaatagg gttagtgatc ttaggtatcc
     8881 tggcgctgtg ctcattaagt tttattcttt ggcgagtggt ttaccgttcc gtatcccgcc
     8941 cgctggcgca acaaacgcag gccttacagc ggctactgga gggcgatatt gactcgccgt
     9001 ttccggaggc ggctggcgtc agcgaactgg ataccatcag ccgtctgatg gaagcgtttc
     9061 gcgccaacgt gcgcaaattg aaccgccatc gtgaggattt ggcggaacag gtgcgatcgc
     9121 aaacggcgga gcttcatgcg ctggtgctgg aacaccggca ggcgcgcgcc gaagcggaaa
     9181 aggccaacga ggcgaaatcg acgttccttg ccgccatgag ccatgaaatt cgcacgccgc
     9241 tttacggcat tctcggtacg gtacaattgc tggccgataa accgctcatg gcaaactacc
     9301 gcgacgattt acaggccatt aatgattcag gcgaatcgct actggcgatt cttaacgata
     9361 ttcttgatta ctcggcgatt gaagtaggcg gcaccaacgt ttccattagc gaggaaccgt
     9421 ttgaaccgcg acaattgttg aatagcgcgc tgcatttaat gcacagccgc gtgcaggtgg
     9481 cgctcatcac cgactttagc gagcaactcc cttccacgct acaaggcgat ccgcgccgga
     9541 tacgtcaaat tgtgattaat cttttaagta atgcggcgaa atttaccgat cgcggcagca
     9601 tagtgctgcg cacgttttgc gacgatcaga gctggtttat tgaggttgaa gataccggat
     9661 gcggtatccc tgaagcgaag ctgacggcta ttttcaaacc gtttgtgcag gcgacaggat
     9721 gccggggcgg gacgggcctg gggctggcta tcagcgccag cctggcagag gcgatgggcg
     9781 ggacgctaac cgtcaccagt acgcttcatg ttggcagttg ttttcgctta caactgccgg
     9841 ttcgccaccc caaacctgca agcaaaagtg cgttcaggga accggtaaat cttaacggac
     9901 tacgcctgtt gctgattgaa gataatatgc tgacgcagcg tattaccgct gaaatgctca
     9961 cgggtaaagg ggtgaaggtc tcagtagctg aaagcgcgaa tgacgcgcta cgctgtttag
    10021 ccgaaggcga gccctttgat gtggcgctgg tggattttga tttaccggat tatgacggct
    10081 taaccctggc gcagcagttg atgagcctgt atcccgccat gaaacgcatt ggttttagcg
    10141 cgcatgtgat agacgataat cttcgtcagc gtaccgccgg tcttttctgc gggattattc
    10201 aaaagcccgt tccccgcgag gagctttacc gcatgatagc gcactattta cagggcaaat
    10261 ctcacaacgc gcgggtgatg ttgaatgaac atcagcttgc cggcgatatg gcgtctgtcg
    10321 gcccggaaaa gctccggcaa tgggtcgcct tattcaaaga cagcgcgctg cctttagtcg
    10381 aggagatcga ggcggcgcgc gccatgaatg acgacgttaa cattaagcgg ctggcgcata
    10441 aattaaaaag cggctgcgcc agcctgggga tgacgcaggc aaccgaagcc tgtcgggagc
    10501 tggaattgca accgcttagc gatatagata ttaaaactat cgtgacgcag ggagtgacgg
    10561 cgctcgacgc atggatagcc ggtcatcctt cgccatgatg atttccggct cgccaaacga
    10621 cgcgtttcac atcgccagtt atcaggacat aaaacagtac gccgagggta taagagggaa
    10681 atagcctacg gctaccgcct gtttaatgat tctgtgtttt ttcgtcctgt agccgtgcct
    10741 gctccgccag ggcggcaaaa tctttttcgc tgtaatagtg cgcgggaggc ggtagctgcg
    10801 ccatatcctc gctgggccac aattgtagct gcgccagcgt gctaagctgg ataccgcgcc
    10861 agcgatgggg caagctcagc ggcaatagcg acgttatctc gccaggaacc gcggtcggca
    10921 ggcggtcatc gcccatctga taattacgat gcagcaccag atatttttcc ggtacccgcc
    10981 gctggctgtt ccaccaacga ccatcaagca tatcaaactg aaaacgggtg atctgcgccg
    11041 gctgcgctgc cagctgcgtc agcgcttgcc gcagcgcagt ttccatcgcc gtgttgtaca
    11101 tctcttgcgt tttcgtctgg ccgtcgacaa ttaaagacgc cgccagacgg gcacccgcga
    11161 ggttagaata gagatcttcc ggcgaaaagg ccgatactcc ctcagaaaat ccgcgaacgg
    11221 actcgaaacc gtaccattgg gcgatttcgt gccactccgc cacctggaac gccagatgcg
    11281 ccgacagcca ggcggccagc gtgtaacgct cgcgtgcatc gaccggaggg gtaaaagcag
    11341 taaagaccag acgccgttcg gccagctcct cgcccagatt cagcgtaaaa gcctgcccca
    11401 gctttggtag tagttggctg aagatataca ctgtcatatc agcggtatcc cgcacatgtg
    11461 cggtgtcgat gaatccgcca cgcaaggtat acacaatacc gttattctca ccgctaaggc
    11521 cgatcaggtt tgccacgccc gagtacagat ggtcgttgta ctgatgatgc cccagcgagt
    11581 ctaccgtcac gacgttattt aactgataaa acggaaccgg cagtcccagc agctcggcat
    11641 gcaggtcgta accaaaagcg caacacggac gcaacccctt tggcagcggc tgtggcggca
    11701 tcgttggcca ggcttcactg gcagcaggca ttgggagcgt ggacagatag agcgtcagtg
    11761 gtaaggcggc gcgggcgctc cccgccagaa acagcagcgc cagaaagata acccgaacga
    11821 tagtcctcaa aatgcctctc ctacctgaaa ataaaaaccg ctgctgcctt tgcccacgcc
    11881 gtaatccagc cgcacgttga cgcgcggctt gaactcaaag cgatagccca cgcccgcaga
    11941 aggcagccat cgcccgtcat ccagatggtg caaagacgat cccatggtgc ccgctcccac
    12001 ccaaccgaca acgccatgcc gccagctcaa cttatggcga tattccagtt ggccactgac
    12061 ggcgttttta tcgcgatagc gcccttcata atagccgcgc atacgatggt tactgcccag
    12121 cagcggcagc atattccatg gcacgtagcc ctgggtaaag gcaccgtcag cttcccaggc
    12181 cagcacgtct ttatcatcaa cggcgtggta ttgactgtag tgcaactggt attcatcgaa
    12241 ccgcgtatcg ctaccgatgt ctggcgcgaa gtgggtatag cgaagggtgg catactgtcc
    12301 tttgcgtggg ttaggcataa aatcacggtc gtcccaacta atctcaacgc taccgccgtt
    12361 actcagtgaa gaaccgccct gcgctgtatg ttgaattctg ggcggatcgt cctcattgat
    12421 ttgcgcggcg tgctgtacat ccagcgtcca gccaacgcca agatagatat tgttgaccag
    12481 ccgacgatac agcatgggtt gcagatccag cacctgcgcg gtataggcct gcttatggct
    12541 gtctttatca ccggcggcaa aaccctgccc ccaatagtaa gtgggcgtgt cgctcaatgc
    12601 gccagtaagg aagaaacgcc agcgatcttg cgcgaaaaag gcgtaatttt gcaggcttac
    12661 gccgaaagcg cccgtggagc taaaatagcc gctcagcgac agcgtggata tctggctaac
    12721 cttatcggca ggatcggggc gatacatacc gacaatggcg gtgccgatgc ccagccccag
    12781 ttcaggggta taaaatggcc cgggcattac tccccagttg acgcctttgg cggcatcgta
    12841 agtatcgcta tcccccattt gttgtagcca gccgtccacc tgactgcggc tgggcagcgc
    12901 cgcctgcgcc acgccggaca gcacaccggc gacgcaaagc aactgtcggc aatggcagcg
    12961 gttcaaaagc gatactcacc ggccacaaag aagctgttgc gctcggcaaa gccaaactcg
    13021 gtggtaacgt tgaaatggcg ggttatttca tactgagcgc ccagcagcat gttccacggt
    13081 gattgcagat gctgtttgac gtcaaagcgg ccgttattgt tatagttagc catactcacc
    13141 agcctttgta gcgtcgctga tggcatggtc aggtcgtcga ggctgccttt aaactcctgc
    13201 tgcacatcct gatacatgct gccgacccag acgtttagct tgcccgacgg cagatgcatc
    13261 ttatctatac ccggggtggt aaaacggtaa ccaacgcgag gtgagacggt aaaggcgtcg
    13321 atgctgccat caagaatatc gaactgtgtc tgggtgtagt tagcatcaac agcggtaaac
    13381 cagttaccta cgccgccgac cagcgtggtg ccgataccat aggtagtgcc tttaaagtcg
    13441 agtttaaact tgaggttttg cagatcggcg ggatgaaaaa cgtggccatt tttcgtcatc
    13501 aacccaacac caatttgcga aacggaatga ccatcggtat agcccaccag gccgtacaca
    13561 ttcataaatg gcagcagcca ggcatccagc ttgaccgttt cggtcttgct cttttcacgg
    13621 gtatgaccga cgttaatttt aaacgcgtta tctaatggaa ttcccccgtt gggacctaaa
    13681 gccaggccat taaagttgat gctatcaacg ttaatattct gcccaatatt catgtagtta
    13741 atattgaggc caaatggctc gggaagctca tagccacgct ttcgggcttc atcacccaga
    13801 aaaggcaaca ctgatgtact ggcaggcttt gccaccggcg ttgtcgcgac tggcggtgtg
    13861 gcagcagatg ggacgtcatc ctgatagcta taaaccggcg acaggttcgc cggggggctg
    13921 gtagccgccc aggtagaaaa agccatagcg ggcagcgcca acagcaaaag ggagcgtttt
    13981 ttcataatga tgaagcgttt attctggcga gaagcgccgc cggatcgaaa ggaggaggga
    14041 gaatatagta atcgtcgcct ggtgggcggg atttctgtgc gaattaatct tttgaaataa
    14101 aaaactattt tctacaacgt ctttgttgca acacattagc ttcatgagtg gaactatcgg
    14161 cccgacggcg atcgggccgg agtgaatcag gacagaacat gttgttcaat cgcccaggca
    14221 acaccatctt caaggttcga tttagtcaca aagttagcca cctctttgac cgacggaatg
    14281 gcgttgtcca ttgccacgcc cataccggcg tattcgatca tcgcaatgtc gttttcctga
    14341 tcgccaatcg ccatcacctc ctctggctta atacccagcg cctcggccag tgattttacg
    14401 ccggtgcctt tattaacccg tttatcgagg atttcaagga agtacggcgc acttttcagc
    14461 acggtatact tttccttcac ctctgccggt atacgcgcaa tcgctcggtc gagaacggca
    14521 ggctcatcga tcatcataac tttcaggaac tgagtgttcg ggtccatctt ctccgcttca
    14581 caaaatacca gcggaatggt cgccacatac gactcatgca ccgtgtagta gctgatatcg
    14641 cggttagcgg tataaagcgt atttcgatct aatgcgtgga agtgagaacc cacctcacgg
    14701 gatagttttt ccagataacg gtagtcatca tagctgagcg ctgtttgcgc taccgtactg
    14761 ccatcccctg ctttctgcac cagcgccccg ttgtaggtga tgcagtagtc gccgggttgt
    14821 tccatatgaa gttctttcag atagctgtgc acacccgcat acggacggcc tgtggtcagc
    14881 accacgttta cccctttttc acgcgcagcg gcaatggcgt ttttaaccgc cggagaaatg
    14941 gtgtgatcgg gcagcaaaag ggtgccatcc atgtcgatag caatgagttt aatagccatg
    15001 aaatccccgc attaaatgag tcctgactca tgctaacgcg attccgctca aaaaacagca
    15061 aaagagtcag ggataaacgg ggctaaagaa taagacaaac cttcctcttt tgctcagtac
    15121 agaaggcgag ttttgtgcag tgaatactca catttattag ataacctcat taatcaaaca
    15181 gaaaataccg tttttctaat ctcatcgata ttgttaccct ggtcatgaat caccctattg
    15241 taaaaataaa caaaaatgat gttaatttaa ttaaaggaga tcgccaaatg tcgatggccc
    15301 ttaccgcccc gcctggcagg aaaagatttt taatcgttgc ctgtctgttt attggaatat
    15361 tcattgccta tctcgaccgc gttaatgttt cggtattagc cgcaaacgaa cccttcttag
    15421 cctatatggg tattgaaggc atgccattgc aaattggcat gatgatgacc gtttttcttg
    15481 ccgcttatgg tatcgctaat gttgtattat caccacttgg cgactacctt ggtccgagaa
    15541 aagcgatgat gctttgtatc ctaatctgga ccatcgcctt aattattggc ggagttgcga
    15601 catcgtttgc attaattatt atttgccgca tattactggg tatcggagag ggtttttatt
    15661 atccgctgca aagcgtattt attaaaaact ggtttccgaa gcaggagcgt ggccgggcaa
    15721 acgcagcgtg gatcgtcggc cagtcggtcg cgcccgccat tgcgatgcct tttttcacct
    15781 ggtggatagg cacccacggc tggcgttcca acttcttttt atgcgccgct ctcgggttaa
    15841 tcccactctg gctactttgg cgatatgttg ctgataaacc agaacaacat aaaagtatca
    15901 gcgagcagga actggcttat atcaaagccg ggcaggaaac ggaaagcgca agcagcagcg
    15961 aaagttttat gttgcgggta aaaccggtga ttaccaacta ttgctactgg ttgctggtgc
    16021 tgtggtacct gtgtctgcaa tgcctgtact gggggatgat tacctggctg ccaacctatc
    16081 ttaaatcagc cagaggattt agctgggcag aaatgggctg gctagcgtcg ctgccgtttg
    16141 tcttgtcgat attttccaaa gccgccgcgg gcgtcttcgt cgataaaata ggacgcagcg
    16201 cccccatatt aatggtgtta atgtttttcg ccggtatcag tatctatttc ggcacaataa
    16261 ccgaacacaa atatatgtca gcggtactac tctccttcgc cgtcgctttt tgcacgatgg
    16321 gtacgcctgt tgcgtggaca ttattacaag ggatggtgtc cgggaaatct atttccgccg
    16381 ccagcggcgt aatgaacggc gtcgcgaacg gcctgtcatc attatcacca gtatttatcg
//
LOCUS       DAJVBX010000096        16439 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.096, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000096 DAJVBX010000000
VERSION     DAJVBX010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 16439)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16439)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16439
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.096"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(62..880)
                     /gene="cof"
                     /locus_tag="OPV72_002601"
     CDS             complement(62..880)
                     /gene="cof"
                     /locus_tag="OPV72_002601"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HMP-PP phosphatase"
                     /protein_id="HCR9914860.1"
                     /translation="MARLAAFDMDGTLLMPDHHLGRETIATLSRLRERDITLTFATGR
                     HVLEMRHILGTLSLDAYLITGNGTRIHSLEGDVLHRQDLDPQVADTVMHHAWDTRASM
                     HVFNDNGWFTGQEIPALLQAHVYSGFRYQVIDIKSIPAHQVTKICFCGDHDDLIRLRI
                     QLNEALEERAHLCFSAVDCLEVLPLGCNKGSALAVLSNHLGLSLADCMAFGDAMNDRE
                     MLGSVGRGLIMGNAMPQLIAALPHLSVIGHCGNQAVSHFLTHWLDNPHLPYSPE"
     gene            980..2680
                     /locus_tag="OPV72_002602"
     CDS             980..2680
                     /locus_tag="OPV72_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SgrR family transcriptional regulator"
                     /protein_id="HCR9914861.1"
                     /translation="MRLLNRLNQYQRLWQPSAGETQHVTVSELAERCFCSERHLRTLL
                     RQAQQAGWLRWEAQSGRGKRGRLQFLVTPESLRTAMMEQALEKGQQLNVLELAQLAPG
                     ELRAMLQPFMGGQWQNDTPTLRIPYYRPLDPLQPGFLPGRAEQHLAGQVFSGLTRFDR
                     DSQYPCGDLAHHWKVSADGLRWDFYIRSTLHWHNGDAVDTAQLHERLERLLTLPALSK
                     LFISVARIEVTHPQCLTFLLHRPDYWLAHRLASYCSGLAHPDLPLIGTGPFRLALFTP
                     ELVRLESHDHYHLSHPLLKAIEFWITPQLFAQDLGTSCRHPVQIAIGKPEELATLSQV
                     SSGISLGFCYLTLKKGSRLNVQQARRLIHIIHHTSLLKTLPVDENLIMPSQGLLPGWT
                     IPQWQDVDETPLPKKLTLAYHLPVELHTMAEQLRHYLATLGCELTLIFHNAKNWNNCP
                     ALAQADLMMGDRLIGEAPEYTLEQWLRCDQIWSHVLDAPAFSHLQATLDALQIQPNEK
                     DRRAALQQVFANLMDDATLTPLFNYHYRISAPPGVNGVRLTPRGWFEFSEAWLPPPSP
                     "
     gene            2745..3440
                     /gene="queC"
                     /locus_tag="OPV72_002603"
     CDS             2745..3440
                     /gene="queC"
                     /locus_tag="OPV72_002603"
                     /EC_number="6.3.4.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-cyano-7-deazaguanine synthase QueC"
                     /protein_id="HCR9914862.1"
                     /translation="MKRAVVVFSGGQDSTTCLAQARHQYDEVHCVTFDYGQRHRAEID
                     VARALALKLGARAHKVLDVTLLNELAVSSLTRDSIPVPDYEPNADGIPNTFVPGRNIL
                     FLTLAAIYAYQVKAEAVITGVCETDFSGYPDCRDEFVKALNHAVNLGMAKDIRFETPL
                     MWIDKAETWALADYWGQLDLVREETLTCYNGIKGDGCGHCAACNLRANGLNHYLSNKA
                     AVMAAMKQKTGLR"
     gene            complement(3547..3945)
                     /gene="fadM"
                     /locus_tag="OPV72_002604"
     CDS             complement(3547..3945)
                     /gene="fadM"
                     /locus_tag="OPV72_002604"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="long-chain acyl-CoA thioesterase FadM"
                     /protein_id="HCR9914863.1"
                     /translation="MQTQIKVRGYHLDVYQHVNNARYLEFLEEARWDGLENSDSFQWM
                     TARNIAFVVVNININYRRPAVLSDLLTVTSQVQQLNGKSGVLSQTITLEPEGQVVADA
                     LITFVCIDLKTQKALPLEGELREKLEQMVQ"
     gene            complement(4049..4423)
                     /locus_tag="OPV72_002605"
     CDS             complement(4049..4423)
                     /locus_tag="OPV72_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HCR9914864.1"
                     /translation="MKHGIKALLITLSLTCAGMAHSALAATPVAKNAAVETKADTPSS
                     SSAKAALPAKASDDEGTRVSINTASAEDLARVMNGVGLKKAQAIVSYREEYGPFKTVD
                     DLKQVPGMGSALVERNLAVLTL"
     gene            complement(4573..6444)
                     /gene="ppiD"
                     /locus_tag="OPV72_002606"
     CDS             complement(4573..6444)
                     /gene="ppiD"
                     /locus_tag="OPV72_002606"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCR9914865.1"
                     /translation="MMDSLRTAANSLVLKIIFVIIIVSFILTGVSGYLIGGSNNYAAK
                     VNGQEISRAQFENAFNNERNRMQQQLGDRYSELAANEGYMKSLRQQVLNRLIDEALLD
                     QYSRELKLGISDEQVKQAIFATPAFQVDGKFDNNRYNAIVNQMGMTADQYTQALRNQL
                     TTQQLINGVAGTDFMLKGETDELAALVSQQRVVREAVIDVNALAAKQQVTDQEVSSYY
                     DQNKVRFMTPEQFRVSYIKLDAATMQAPVSDADIQAYYDQHVDQFTQPERIRYSIIQT
                     KTEDDAKAVLDALNKGEDFATLAKEKSTDIISARNGGDMGWLEESATVPELKNAGLKE
                     KGQISGVIKSSVGFLVARLDDIQPAKVKPLSEVRDDIAAKVKQEKALDAYYALQQKVS
                     DAASNDNESLAGAEQVAGVKAVETGWFSRDTLPEELNFKPVADAIFNGGLVGENGTPG
                     PNSDIITVDGDRAFVVRVSEHKPEAVKPLAEVKEQVTALVKHNKAEQQAKLDAEKLLV
                     ELKAGKGAEAMKAAGLSFGEPKTLSRTSQDPVSQAAFALSLPTKDKPVYGVANDMQGN
                     VVLLAFDEVKAGAMPEAQKKAMVQGITQNNAQIVFEALMSNLRKEAKIKIGDALEQQ"
     gene            complement(6735..7007)
                     /gene="hupB"
                     /locus_tag="OPV72_002607"
     CDS             complement(6735..7007)
                     /gene="hupB"
                     /locus_tag="OPV72_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016535194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein HU-beta"
                     /protein_id="HCR9914866.1"
                     /translation="MNKSQLIEKIAAGADISKAAAGRALDAIIASVTESLKEGDDVAL
                     VGFGTFAVKERAARTGRNPQTGKEITIAAAKVPSFRAGKALKDAVN"
     gene            complement(7216..9570)
                     /gene="lon"
                     /locus_tag="OPV72_002608"
     CDS             complement(7216..9570)
                     /gene="lon"
                     /locus_tag="OPV72_002608"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001469947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HCR9914867.1"
                     /translation="MNPERSERIEIPVLPLRDVVVYPHMVIPLFVGREKSIRCLEAAM
                     DHDKKIMLVAQKEASTDEPGVNDLFTVGTVASILQMLKLPDGTVKVLVEGLQRARISA
                     LSDNGEHFSAKAEYLDSPAIDEREQEVLVRTAISQFEGYIKLNKKIPPEVLTSLNSID
                     DPARLADTIAAHMPLKLADKQSVLEMSDVNERLEYLMAMMESEIDLLQVEKRIRNRVK
                     KQMEKSQREYYLNEQMKAIQKELGEMDDAPDENEALKRKIDAAKMPKEAKEKAEAELQ
                     KLKMMSPMSAEATVVRGYIDWMVQVPWNARSKVKKDLRQAQEILDTDHYGLERVKDRI
                     LEYLAVQSRVNKIKGPILCLVGPPGVGKTSLGQSIAKATGRKYVRMALGGVRDEAEIR
                     GHRRTYIGSMPGKLIQKMAKVGVKNPLFLLDEIDKMSSDMRGDPASALLEVLDPEQNV
                     AFSDHYLEVDYDLSDVMFVATSNSMNIPAPLLDRMEVIRLSGYTEDEKLNIAKRHLLP
                     KQIERNALKKGELTVDDSAIIGIIRYYTREAGVRSLEREISKLCRKAVKQLLLDKSLK
                     HIEINGDNLHDYLGVQRFDYGRADSENRVGQVTGLAWTEVGGDLLTIETACVPGKGKL
                     TYTGSLGEVMQESIQAALTVVRARAEKLGINPDFYEKRDIHVHVPEGATPKDGPSAGI
                     AMCTALVSCLTGNPVRADVAMTGEITLRGQVLPIGGLKEKLLAAHRGGIKTVLIPFEN
                     KRDLEEIPDNVIADLDIHPVKRIEEVLTLALQNEPSGMQVVTAK"
     gene            complement(9756..11027)
                     /gene="clpX"
                     /locus_tag="OPV72_002609"
     CDS             complement(9756..11027)
                     /gene="clpX"
                     /locus_tag="OPV72_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001396736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATP-binding subunit ClpX"
                     /protein_id="HCR9914868.1"
                     /translation="MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLC
                     NDIIREEIKEVAPHRERSALPTPHEIRTHLDDYVIGQEQAKKVLAVAVYNHYKRLRNG
                     DTSNGVELGKSNILLTGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVEN
                     IIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGT
                     VAAVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVIANRVETGSGIGFGATVKA
                     KSDKASEGELLSQVEPEDLIKFGLIPEFIGRLPVVATLNELSEEALVQILKEPKNALT
                     KQYQALFNLEGVDLEFRDEALNAIARKAMARKTGARGLRSIVEAALLDTMYDLPSMED
                     VEKVVIDESVIAGQSKPLLIYGKPEAQASGE"
     gene            complement(11279..11902)
                     /gene="clpP"
                     /locus_tag="OPV72_002610"
     CDS             complement(11279..11902)
                     /gene="clpP"
                     /locus_tag="OPV72_002610"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006809880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HCR9914869.1"
                     /translation="MSYSGERDNLAPHMALVPMVIEQTSRGERSFDIYSRLLKERVIF
                     LTGQVEDHMANLIVAQMLFLEAENPEKDIYLYINSPGGVITAGMSIYDTMQFIKPDVS
                     TICMGQAASMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGYQGQATDIEIHAREILKVK
                     GRMNELMAHHTGQSLEQIERDTERDRFLSAPEAVEYGLVDSILTHRN"
     gene            complement(12149..13447)
                     /gene="tig"
                     /locus_tag="OPV72_002611"
     CDS             complement(12149..13447)
                     /gene="tig"
                     /locus_tag="OPV72_002611"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001716227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HCR9914870.1"
                     /translation="MQVSVETTQGLGRRVTITIAADSIETAVKSELVNVAKKVRIDGF
                     RKGKVPMNIVAQRYGASVRQDVLGDLMSRNFVDAIIKEKINPAGAPNYVPGEYKVGED
                     FTYSVEFEVYPEVELTGLESIEVEKPVVEVTDADVDVMLDTLRKQQATWKEKDGAADA
                     EDRVTIDFTGSVDGEEFEGGKATDFVLAMGQGRMIPGFEDGVKGHKAGEEFTIDVTFP
                     EEYHAENLKGKAAKFVINLKKVEERELPELTEEFIKRFGVEDGSVAGLRAEVRKNMER
                     ELKGAVRNRVKSQAIEGLVKANDIDVPSALIDSEIDVLRRQAAQRFGGNEKQALELPR
                     ELFEEQAKRRVVVGLLLGEVIRTNELKADEERVKGLIEEMASAYEDPKEVIEFYSKNK
                     ELMDNMRNVALEEQAVEAVLAKAKVSEKATSFNELMNQQA"
     gene            complement(13794..14111)
                     /gene="bolA"
                     /locus_tag="OPV72_002612"
     CDS             complement(13794..14111)
                     /gene="bolA"
                     /locus_tag="OPV72_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator BolA"
                     /protein_id="HCR9914871.1"
                     /translation="MMIREQIEEKLRTAFDPVFLEVVDESYRHNVPAGSESHFKVVLV
                     SDRFTGERFLNRHRMIYGTLTAELSTTVHALALHTYTLKEWEGLQDTIFASPPCRGAG
                     SIA"
     gene            14415..14993
                     /locus_tag="OPV72_002613"
     CDS             14415..14993
                     /locus_tag="OPV72_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005225436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCR9914872.1"
                     /translation="MLKKLLFPLVALFMLAGCATPPTTIDVAPKITLPQQDPSLMGVT
                     VSITGADQRQDQALAKVTRNNQLVTLTASRDLRFLLQEVLEKQMTARGYMIGPNGAVN
                     LQIIVNQLYADVSQGSVRYNIATKADIAIIATAANGNKMTKNYRANYSIEGAFQASNQ
                     NIADAVNSVLTDTIADMSQDTSIHDFIKQNAR"
     gene            15037..>16439
                     /gene="ampG"
                     /locus_tag="OPV72_002614"
     CDS             15037..>16439
                     /gene="ampG"
                     /locus_tag="OPV72_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="muropeptide MFS transporter AmpG"
                     /protein_id="HCR9914873.1"
                     /translation="MSSQYLRIFQQPRSAILLILGFASGLPLALTSGTLQAWMTVENI
                     DLKTIGFFSLVGQAYVFKFLWSPLMDRYTPPFLGRRRGWLLATQLLLLAAIAAMGFLE
                     PGTQLRWMAALAVVIAFCSASQDIVFDAWKTDVLPAEERGAGAAISVLGYRLGMLVSG
                     GLALWLADRWLGWQGMYWLMAALLIPCIIATLLAPEPTDTIPSPKSLEQAVVAPLRDF
                     FGRNNAWLILLLIVLYKLGDAFAMSLTTTFLIRGVGFDAGEVGVVNKTLGLLATIVGA
                     LYGGILMQRLSLFRALLIFGILQGASNAGYWLLSITDKNMFSMGAAVFFENLCGGMGT
                     AAFVALLMTLCNKSFSATQFALLSALSAVGRVYVGPVAGWFVEAHGWPTFYLFSVVAA
                     VPGLLLLLVCRQTLEYSWQSERFIPRTQYRGTYNFALSILLAGVALLAVWVLLLTMNA
                     LDYTNFSFLPELLETAVA"
BASE COUNT         3654 a         4612 c         4001 g         4172 t
ORIGIN      
        1 tgggggtttt ccatagacaa aaaaagccag actgaatgtt tggcttgctg gaagagatct
       61 ctcattcggg ggaataaggt agatgcggat tgtccagcca atgcgtcaaa aagtgtgata
      121 ccgcttgatt accacaatgt ccgataaccg aaaggtgtgg cagcgcggcg ataagctgcg
      181 gcatggcatt gcccataatg agcccccgcc cgacgctgcc cagcatttcc cgatcgttca
      241 tcgcgtcgcc aaacgccatg caatctgcca gtgaaagccc taaatggttg ctcaataccg
      301 ccagcgccga tcctttattg caccccagcg gtagcacttc caggcagtcg acggcagaga
      361 aacagaggtg cgcgcgttct tccagcgcct cattgagctg aatgcgcaaa cggatcagat
      421 cgtcatgatc gccgcaaaaa cagatcttcg tcacctgatg ggccggaata ctttttatat
      481 cgataacctg ataacgaaag ccgctgtaga cgtgcgcctg gagtagcgcg gggatctcct
      541 ggcctgtaaa ccagccgttg tcattaaaca catgcatact ggctcgggta tcccaggcat
      601 ggtgcatcac cgtatcggca acctgaggat cgagatcctg acgatgcagc acgtcgcctt
      661 ccagcgagtg aattcgcgtc ccgttaccgg taataagata agcatccagt gaaagcgtcc
      721 ccagaatatg ccgcatctcc agcacgtgac gacccgtagc gaatgtcaga gtgatatcgc
      781 gttcgcgcag acgcgacagc gtggcgatcg tttctctacc caaatggtga tcgggcatta
      841 ataacgtgcc atccatatca aatgctgcca gacgggccat ctctttctcc acactgtaac
      901 gcggttaact tgttgttcag tattacctga gatatacgga agtaatagtg aacagataaa
      961 aggaagtgtt ccgggtttta tgaggctact gaatcggctt aatcaatatc aacgcctctg
     1021 gcagccttcc gccggggaaa cgcaacatgt caccgttagc gaactggccg aacgctgttt
     1081 ttgtagcgag cgccatctgc gaacgctgct gcgtcaggcc cagcaggcgg gttggctaag
     1141 atgggaggcg cagtccgggc gcgggaaacg tggacggctc cagtttctgg tcacgccgga
     1201 atcgctccgc accgccatga tggaacaggc gctggaaaaa gggcagcagc tcaacgtact
     1261 ggaactggcg cagctggcgc ctggcgagtt acgggcgatg ctccagcctt ttatgggcgg
     1321 ccaatggcaa aacgatacgc caacattgcg tattccctac tatcgtccgc ttgatccgct
     1381 gcagccgggt ttcctgccag gacgcgcgga acagcatctc gcagggcaag ttttttccgg
     1441 gttaacgcgc ttcgatcgcg atagccaata tccttgcggg gatttggcgc atcactggaa
     1501 ggtttccgcc gacggtttac gctgggattt ttatattcgc tccacgctgc actggcataa
     1561 tggcgatgcg gtggataccg cgcagttaca cgaacgcctg gaaaggctgc ttaccctacc
     1621 ggcgctaagc aaattgttta ttagcgtcgc acggatcgaa gtaacgcatc ctcagtgcct
     1681 gacctttctc cttcaccgac ctgattactg gctggcgcat cgtctggcga gctattgtag
     1741 cggtctggcg catcctgacc tgccgcttat cggcaccggt ccttttcgcc tggcgttgtt
     1801 cacgccggaa ctggtgcgtc tggaaagtca tgaccattat cacctcagcc atccgctgct
     1861 gaaagcgatt gaattctgga tcaccccgca actgtttgcc caggatctgg gcaccagttg
     1921 ccgccatccg gtgcagattg ccatcggcaa accggaagag ctggcgacgc tgagtcaggt
     1981 aagtagtggt atcagtcttg gcttttgtta tttaaccctc aaaaagggct cacggctcaa
     2041 cgtacagcag gcgcggcgtc tgatacatat tatccatcat acttcgctgc tgaaaacctt
     2101 accggtagat gagaacttga ttatgccaag tcaggggctg ctacccggct ggacaatccc
     2161 gcaatggcag gacgttgatg aaacaccatt gccgaaaaaa cttaccctgg cgtatcacct
     2221 tcccgtagag ctgcatacga tggcggaaca gcttcgacat tacctggcga cgctcggctg
     2281 tgagttaacg ttgatttttc ataatgccaa aaactggaat aactgccctg cgttggcgca
     2341 agcggatctg atgatgggcg acaggctgat cggcgaagcg ccggaatata cgctggagca
     2401 gtggctacgt tgcgatcaga tctggtcaca tgtcctggac gcgcctgcgt tttcccatct
     2461 gcaggctacg cttgacgctc tgcaaattca gcccaatgaa aaagatcgcc gcgccgcgct
     2521 acaacaagtt tttgccaacc tgatggatga cgccacactt acgccgctgt ttaattatca
     2581 ctatcgcatc agcgccccac cgggcgttaa cggcgttcga ctcacccctc gcggctggtt
     2641 tgaatttagc gaagcctggc ttccgccgcc ttcgccgtga agaagctggt cgggattatc
     2701 cgtacgcgtt accatattgg ctttcgtcat tgatcaggat aactatgaaa cgcgccgttg
     2761 ttgtatttag tggaggtcag gactccacca cttgtctggc gcaagcgcgg catcagtatg
     2821 atgaagtgca ttgtgtcacg tttgattatg gtcagcgcca ccgcgcagag attgatgttg
     2881 cgcgcgcact ggcgttaaaa cttggcgcac gcgcgcataa agtgctggat gtcactttgc
     2941 tgaacgaact ggcggtcagc agcctgacgc gggatagcat tccggtgccg gactatgaac
     3001 cgaacgctga cggtatcccc aacactttcg taccgggacg caatattctc tttctgacgc
     3061 tggcggcgat ttacgcttat caggtcaaag ccgaggcggt gatcaccggc gtttgcgaga
     3121 ccgatttttc cggctatcca gactgtcgcg atgagttcgt caaagcgctg aatcacgcgg
     3181 tgaatctggg catggcgaaa gatatccgtt tcgaaacgcc cctaatgtgg attgataaag
     3241 ctgaaacctg ggcgctggcc gattattggg gccaactgga tttagttcgc gaagagacgc
     3301 tgacctgcta taacggcatt aaaggcgatg gctgtggtca ttgcgcagcc tgtaatctgc
     3361 gcgctaacgg cctgaatcat tatctgtcga ataaagcggc ggtgatggcg gcaatgaagc
     3421 aaaaaaccgg gttaaggtga ttgttttgcc ggatggcggc gcacgcacct tatccgtgcc
     3481 tggcgatatg caccatggtc aatatcgcca ggccggacaa gttcaacgcc atcagacagc
     3541 gaggcgttat tgcaccatct gttccagctt ttcacgcaat tcgccttcca gcggcagcgc
     3601 tttttgcgtt tttaaatcaa tacaaacaaa cgtgatgagc gcatcggcca ccacctgccc
     3661 ttctggctcc agcgtaatcg tctggcttaa tacgccgctt ttaccgttaa gctgttgtac
     3721 ctggctggtc acggtcagta gatcgctcaa taccgccggg cgacggtaat ttatattgat
     3781 gtttaccacc acaaaggcaa tattgcgggc cgtcatccac tgaaagctgt cgctgttttc
     3841 cagcccatcc caacgggcct cttccagaaa ttccagatag cgggcattat taacatgttg
     3901 ataaacatca agatgatatc cacgaacttt gatttgtgtt tgcatagcgc aataacctta
     3961 cgttgttgtt ataagtaagc gacaagtaca gaggtcataa ctggtatgac ctctacagtc
     4021 tggcaaattt tggccactgt gcaagtgatt acaatgttaa aactgccaga ttacgctcca
     4081 ccagcgcgct tcccattccc ggcacctgct ttaaatcatc caccgtttta aaaggaccat
     4141 actcctcccg atagctcaca atagcctgcg cttttttcag cccaacgccg ttcatcaccc
     4201 gcgccagatc ctccgcagac gcggtattaa tgctcaccct agtaccttca tcatcgctgg
     4261 ctttagcagg taatgccgct ttggcggagg atgaagaagg cgtatccgct tttgtttcca
     4321 ccgctgcatt ttttgcgaca ggcgtcgccg ccagcgcgct atgggccatg cccgcgcagg
     4381 ttaaagaaag cgtaataagc agtgctttaa ttccgtgttt catactgttt tctccttgtt
     4441 tgttaacagt gcagccacga tagcggggcg gagaaaaacg aacaaatggc aattctcaga
     4501 aatggaaaag gccgcgaaag cggcctttgt gggatacaac gttttgcaat tttttgcgaa
     4561 gcgcctcgac gattactgct gttccagagc gtcgccgatt ttgattttcg cctctttacg
     4621 cagattgctc atcagcgcct caaagacaat ttgcgcattg ttctgcgtga tgccctgcac
     4681 catcgctttt ttctgcgctt ccggcatggc gcccgctttc acctcgtcaa acgccagcag
     4741 aacgacgtta ccctgcatat cgttcgccac gccataaact ggcttatctt tcgtcggaag
     4801 gcttaacgca aaggccgcct gactcaccgg atcctgactg gtacgactta acgttttagg
     4861 ctcgccaaaa ctcagacccg ccgctttcat cgcttccgcg cctttgcccg ctttcagctc
     4921 gaccagcagt ttttccgcat ccagcttcgc ctgttgttcc gctttgttat gcttcaccag
     4981 ggcagtgacc tgttctttca cttctgccaa cggcttcacg gcttcaggtt tatgttcgct
     5041 cacgcgcaca acaaaagccc ggtcgccatc tacggtgata atgtctgaat tcggccccgg
     5101 cgtaccgttt tcgcctacca gaccgccatt aaagatagca tcggctaccg gtttgaagtt
     5161 cagctcttcc ggtaaggtgt cacggctaaa ccagccggtt tcaacggctt ttacgccagc
     5221 gacctgttca gcgcctgcta acgactcatt gtcgttgctt gccgcatcgc tcaccttctg
     5281 ctgcaacgca tagtaagcat ccagcgcttt ttcctgtttc actttcgcgg caatgtcgtc
     5341 gcgaacctcg cttaacggtt tcactttggc aggctgaata tcatccagac gcgccaccag
     5401 aaaaccgaca gacgacttaa tcacgccaga tatctggcct ttttctttta atccggcgtt
     5461 tttcagttcc ggcaccgtgg cagactcttc cagccagccc atatcgccgc cattacgcgc
     5521 agagatgata tcggtagatt tctctttcgc cagcgtggcg aaatcttcgc ccttgttcag
     5581 cgcatccagt accgctttcg catcatcttc cgttttggtc tgaataatgc tgtaacgaat
     5641 gcgctccggc tgagtaaact gatctacatg ctggtcataa taggcctgaa tatccgcatc
     5701 gctgaccggt gcctgcatcg tcgcggcatc cagcttgata tagcttacgc ggaactgttc
     5761 cggcgtcata aagcggactt tattctgatc gtagtagctg gacacttcct gatcggtcac
     5821 ctgctgcttc gccgccagcg cgttgacatc aataacggct tcacgcacca cgcgctgttg
     5881 agagactaat gccgccagtt cgtcggtttc ccctttcagc ataaaatcag taccggccac
     5941 gccgttgatc agttgctgag tggtaagctg gttacgcagc gcctgagtat actgatcggc
     6001 cgtcattccc atctgattca caatcgcgtt atagcggttg ttgtcaaact taccgtccac
     6061 ctgaaaagcg ggagtggcga aaatcgcctg ctttacctgc tcatcgctga tgcccagttt
     6121 cagttcgcgg gaatattgat ccaacagcgc ttcatctatc agacgattca gcacctgctg
     6181 gcgcaggctt ttcatataac cttcgttggc cgccagttca gaatacctgt cgcccaactg
     6241 ctgctgcata cggttacgtt cgttgttaaa cgcattctca aactgtgccc ggctgatttc
     6301 ctggccattc acttttgcgg cgtagttatt gcttccgcca atcaggtaac cactaacgcc
     6361 ggtcaaaatg aacgacacga taatgataac gaaaataatc ttgagcacga gactgtttgc
     6421 agccgtgcgt aagctgtcca tcatggtgta accacactcc gctgtaggtg actttacact
     6481 ttatctttca ggcggcttct ctgctggcta ctgagtgctt cgctcagtag ccgcgtcgac
     6541 gcaacctgaa tgatttgcgt atatagactt cacgcgcatc gcattttctg aacgcggcgc
     6601 acaaaagcct attgtgacaa gaaacgaggg caattgtcag cccgcaacgc acagaaagtc
     6661 ccgaatcgcc aataaaaaag gcacatcagt tgatgcgccc ttgtactttg tcacatcccc
     6721 cgaggggatc acgcttagtt taccgcgtct ttcagcgctt tacctgcacg gaaactcggc
     6781 actttggcag cggcgatggt gatctcttta cctgtttgcg ggttgcgacc agtacgggca
     6841 gcacgctctt taacagcaaa agtaccaaag cctaccagtg caacgtcatc cccttctttc
     6901 agagattcgg taacagaagc aataatcgca tctaacgcac gtccagccgc agccttagag
     6961 atatcagccc ctgcagcaat tttttcgatc agttgagatt tattcactct tctcttcctc
     7021 tttataattt atatcgcacc tgaatccttc gaagtacgac cgcgcagcag ttatatcagg
     7081 cctgccacgc ccttacaaca cccgttaatg gtggcagacc caatcaacca tctaaattag
     7141 ctatacaaaa aaaggctggc aagtccgaaa tagcctgcca gccctgtttt tattagcgct
     7201 atttgcgcga ggtcactatt ttgcggttac aacctgcatt ccagacggtt cgttttgcag
     7261 agcaagcgtc agaacttcct caatgcgctt cacaggatga atatccagat cggcaatcac
     7321 gttgtccgga atttcctcca gatcacgttt attttcgaat ggaattaaga ccgttttaat
     7381 cccgccgcga tgcgccgcca acagtttttc tttcaggccg ccgatcggca acacctgacc
     7441 acgcagcgtg atctcaccgg tcattgccac atctgcgcgc accggattac cggtcaggca
     7501 ggaaaccagc gcggtacaca tcgcgatacc ggcgcttgga ccgtctttcg gcgttgcgcc
     7561 ttccggcacg tgaacgtgga tatcgcgttt ttcgtaaaag tccggattaa tacccagttt
     7621 ttccgcgcgc gcgcgcacca cggtcagcgc cgcctgaata gattcctgca tcacttcacc
     7681 gagcgagccg gtgtaggtca gcttgccttt gcccggtacg caggcggttt cgatggtcaa
     7741 cagatcgccg cccacttccg tccacgccag ccccgtcacc tgacccacgc ggttttcgct
     7801 atccgcgcgg ccataatcaa agcgctgcac accgaggtag tcgtgcagat tatcgccgtt
     7861 aatttcaata tgttttaacg acttatcgag caacagttgt ttaaccgctt tacggcacag
     7921 tttggagatt tcacgctcca gactacgaac gcccgcttca cgcgtgtaat agcggataat
     7981 accgataatc gcgctatcgt cgaccgtcag ttcgcctttc ttcagcgcgt tacgctcgat
     8041 ctgcttcggc agcaggtgac gtttagcaat attcagcttc tcgtcttcgg tataaccgga
     8101 cagacggatc acttccatac gatccagcag cggcgccgga atgttcatgg agttggaggt
     8161 ggcgacgaac atcacatcgc tgagatcgta atccacttcc aggtaatgat cgctgaacgc
     8221 cacgttctgc tccgggtcca gcacctcaag cagtgcggaa gccggatcgc cgcgcatgtc
     8281 cgaggacatt ttgtcgatct catcgagcag gaatagtggg tttttaaccc ccactttggc
     8341 cattttttgg atcagtttac ccggcataga gccaatgtaa gtccggcgat gaccgcggat
     8401 ttccgcttca tcacgcacgc cgcccagcgc catacggacg tatttacgcc ctgtggcttt
     8461 agcgatggac tggcccaacg aggttttacc tacccccggc ggccccacca gacacaggat
     8521 cggccccttg attttattta cacggctttg taccgcgaga tactcaagga tgcggtcttt
     8581 cacacgctcc agaccataat ggtcagtatc gaggatttcc tgcgcctgac gcaggtcttt
     8641 tttgaccttg ctacgcgcat tccacggcac ctgcaccatc cagtcgatgt agccgcgcac
     8701 cacggtcgct tccgccgaca tcggagacat cattttcagc ttctgcagtt ccgcttccgc
     8761 tttctctttc gcctctttcg gcattttcgc cgcgtcgatc ttacgcttca gcgcttcgtt
     8821 ttcgtccggc gcgtcgtcca tctcgccaag ttctttctga atcgctttca tttgctcgtt
     8881 cagatagtac tcgcgctggg atttctccat ctgctttttc acgcggttgc gaatgcgttt
     8941 ctcaacctgc agcagatcga tttcagattc catcatcgcc atcagatatt ccagacgttc
     9001 gttaacgtcg gacatctcca gtacggactg tttatccgcc agtttcagcg gcatatgcgc
     9061 ggcgatggtg tcagccagac gtgcagggtc gtcaatgcta ttgagtgacg tcagcacttc
     9121 cggcggaatt tttttgttca gcttgatgta gccttcgaac tggctgatag cggtacgcac
     9181 cagcacttct tgttcacgct catcaatggc tggcgaatca aggtactccg ccttcgcgga
     9241 gaaatgttcg ccgttgtcag acagcgcgga aatacgcgcg cgctgtaacc cctcaaccag
     9301 cacttttacg gtgccgtcag gcagtttcag catctgcaaa atagaggcca cggtcccgac
     9361 ggtgaaaaga tcgtttacac ccggctcatc cgttgatgct tccttctggg cgaccagcat
     9421 gattttttta tcatggtcca tagccgcttc cagacaacgg atagattttt cccgccctac
     9481 aaataagggt atgaccatgt gcggataaac caccacatcg cgcaagggca atacggggat
     9541 ttcaatgcgt tcagaacgct caggattcat agagctctct cttagtttag tgtccgccag
     9601 gtaatcagat agtatagctg tgctccatac cacctataac atgtacgtca gtatatgggg
     9661 atgtttccca cacattcaac ggcgtgttta caggaaaaac gaaaggggag ataaaatccc
     9721 cccttttttg gctaactgat tgtatgaatg tttaattatt cgccagaagc ctgcgcttcc
     9781 ggtttgccgt aaatcagcaa cggcttactc tgaccggcaa taacggactc gtcaatcacc
     9841 actttttcga cgtcttccat agatggcaaa tcgtacatgg tatccagcag cgccgcttcg
     9901 acgatagaac gcaggccacg ggcaccagtt ttacgcgcca tcgctttcct ggcgatagcg
     9961 ttcagcgctt cgtcacggaa ttccagatcg acgccttcca ggttaaacag cgcctgatac
    10021 tgcttggtca gcgcattttt cggctctttc aggatttgaa ccagcgcttc ttcgctgagt
    10081 tcgttcagcg tcgccaccac tggcagacga ccgataaact caggaatcag accaaatttg
    10141 atcaaatctt ccggttcaac ctgcgacaac agctcgcctt cactggcttt gtcggacttc
    10201 gctttcaccg tcgcgccaaa accaatgccg gagccggttt caacacggtt agcgatcact
    10261 ttatccagac cggcaaacgc gccgccgcag ataaacagaa tcttagaggt atctacctgt
    10321 aagaactcct gctgcggatg tttgcgaccg ccctgcggtg gaaccgcggc gacggtgcct
    10381 tcgatcagtt tcagcaacgc ctgctgtacg ccttcgccgg aaacatcgcg ggtaatggac
    10441 ggattgtctg atttacgcga aatcttatcg atttcatcaa tgtagacaat cccacgctgc
    10501 gctttttgca cgtcgtagtc gcatttctgc aacagtttct gaatgatatt ctcgacgtct
    10561 tcccccacgt aacccgcttc ggtcagcgtg gtcgcatccg ccatagtgaa cggcacatcc
    10621 agcaagcgcg ccagcgtttc cgccagcagc gttttaccgg aaccggtcgg tccagtcagc
    10681 agaatgttgc ttttgcctaa ctcgacgcca ttgctggtat cgccgttacg cagacgcttg
    10741 tagtggttat agaccgccac cgccagcact tttttcgcct gctcctggcc gataacgtaa
    10801 tcgtccaggt gagtacgaat ttcatgcggc gtcggcagcg cactacgttc acggtgcgga
    10861 gcaacttctt taatttcttc gcgaataatg tcgttacata aatcgacgca ttcgtcgcag
    10921 atatacacgg atggaccggc aatcagcttg cgcacttcat gctggctttt gccgcaaaaa
    10981 gagcagtaca acaatttgcc cgagccatct ttgcgtttat ctgtcatgag tcaaaacctc
    11041 ttctttgttc tttgtgccgc acacgacgac gcaaatgcca ttctcaggcg caagccgcta
    11101 atcagcgttg tgccgccctt cattagtata tacacaaaat cattcgagct acatcaaggc
    11161 ggcaactcag cgactccgca ggcgcttaca taagtaagtc actgggaggc gcgctggcaa
    11221 ccaacaccga ggtagcgtga aggatgaagt gtatagcggc acacttgcgt ccagggcatc
    11281 aattacgatg ggtcaaaatt gagtcaacca aaccgtactc taccgcttca ggcgcggaga
    11341 ggaagcgatc gcgctcagta tcacgttcaa tctgctcaag agattgaccc gtatgatgcg
    11401 ccataagttc attcatgcgc ccttttactt tcaaaatttc gcgggcgtga atttcaatat
    11461 ccgtcgcctg gccctgatag ccgcccagcg gctggtggat catgacgcga gagttcggca
    11521 agcagaaacg tttgcctttc gccccggcag tcagcagaaa cgcccccata gaggccgcct
    11581 gtcccataca aatggtgctg acgtctggct taataaactg catggtgtca tagatggaca
    11641 tccccgcagt aattacgccg ccaggagaat taatgtacag atagatatct ttttccgggt
    11701 tttccgcttc caggaacagc atctgcgcca cgatcaggtt agccatatgg tcttcgacct
    11761 ggccggtcag aaatatgacg cgttccttaa gtagacgaga atagatatca aaagagcgct
    11821 caccgcgtga ggtctgttca atgaccatcg gcaccagcgc catatgaggg gccaaattat
    11881 ctcgttctcc gctgtatgac atttccgtct cctggataaa aattgaaaaa atctgctgta
    11941 ctgattgtaa cctgatggac ggattatcag ccagtccctc tgtaatgggt acggcatcgc
    12001 cataattcaa gcataacaat cttttgctct aacgctaaca ctgaaacgcg gttttcgcac
    12061 ccttaccacg caaaatgcgt gacaaaaaaa acccgtcact gaaaggtgac gggtttttgt
    12121 gcaaatttcg tgcttttaac gcgaaaaatt acgcctgctg gttcatcagc tcattgaagg
    12181 aagtggcttt ttcagacact ttcgcttttg ccagaaccgc ttcaacagcc tgttcttcca
    12241 gagcgacgtt acgcatattg tccatcagct ctttattttt gctgtagaac tcaatcactt
    12301 ctttcggatc ttcgtaagca gaggccatct cttcgatcag gcctttaacg cgttcttcgt
    12361 ccgctttcag ctcgttggta cgaatgactt cgccgagcag cagaccgaca actacacgac
    12421 gcttagcctg ttcttcgaac agttcgcgcg gcagctccag agcctgtttc tcgttaccac
    12481 caaaacgctg cgcagcctga cgacgcagaa cgtcgatttc gctgtcgatc agcgcagacg
    12541 gtacgtcgat gtcgttagct tttaccagac cttcgatcgc ctgagactta acgcggttac
    12601 gcaccgcgcc tttcagctcg cgttccatgt ttttacgtac ttcagcgcgc agaccggcta
    12661 cggaaccatc ttcaacgccg aaacgtttga tgaattcttc ggtcagttcc ggcagttcgc
    12721 gttcttcaac tttcttcagg ttgataacga acttagccgc tttacctttc aggttttcag
    12781 cgtggtactc ttccgggaag gtcacatcga tagtgaactc ttcgccagct ttgtggcctt
    12841 taacgccgtc ttcaaagccc ggaatcatac gaccctggcc catcgccaga acgaaatcgg
    12901 tcgctttgcc gccttcgaac tcttcgccgt ctacagagcc ggtgaaatcg atggtcacgc
    12961 ggtcttccgc atccgcagcg ccgtcttttt ctttccaggt cgcctgctgc ttacgcaggg
    13021 tgtccagcat cacatcaacg tcagcgtcgg tgacttcaac aaccggcttt tcaacttcga
    13081 tggattcgag gccagtcagc tcaacttccg gatagacttc aaactcgacg gagtaagtga
    13141 agtcttcacc cactttgtat tcgcccggaa catagttcgg cgcgcctgcc gggttaattt
    13201 tttctttgat gatcgcgtca acgaagttgc ggctcatcag atcgcccagc acgtcctggc
    13261 gaacagaagc gccataacgc tgagcgacga tattcatcgg tactttgcct ttacggaagc
    13321 cgtcaatacg tacttttttc gctacgttga ccagctcgct ttttacagcg gtctcgatgc
    13381 tgtcagcagc gattgtaatc gttacacggc ggccaaggcc ctgagtggtt tcaactgaaa
    13441 cttgcatctt gttacctcaa aaaatcacag tgctcggtca actctactcc gcaagcacgt
    13501 gctatttgct tcgcggaacc gggatgttct cataatcaat cacattccct gtcgtcagaa
    13561 tcatcccgaa gacgttcata tataagacgg cgcattatag cggcatcact tttgtgagtc
    13621 gagaacggtg attgtgcgat gctgcggcgg ttttcacaat tctcggctaa tttttgtctg
    13681 aatactgtac gacacgctca aaattcagac aaaataaaac ggcccgcagg ccgttttcac
    13741 ataattctgt agcaacatac tggaaaagcg gaggtagttg caaatccgtt ttgctacgcg
    13801 atgcttcccg cgccgcgaca aggaggcgac gcgaagatag tatcctgcaa tccttcccac
    13861 tctttgaggg tataagtatg cagtgccagc gcatgtacgg ttgtggaaag ttccgccgtt
    13921 aacgtaccgt aaatcatccg atgacgatta agaaaacgtt cgcctgtaaa gcgatcgctc
    13981 accagcacga ccttaaaatg gctttccgat cctgctggaa cattgtgacg atagctttca
    14041 tccacaactt cgagaaacac ggggtcgaac gctgtcctta atttttcttc tatttgctca
    14101 cgtatcatca tgaaaatctc ctccgacaac gctgtgatgt cacccatccc tttaaatact
    14161 agccgctttt accgtttcca ttacagcatg acaacaaaaa tttagctttc gtctgattat
    14221 ttcagccaaa cgtatgaagt ttactgcctt aatcattctt ttagcgctca aaatccccgc
    14281 tcgcgccgtt atcaatacca aatcggacat tacgacgaat ttacctgcgt tgaccacttc
    14341 ccctcgccgt tagcggtgtt atgatggcgg gaatttttac ctatcacgtt ttaagcgtca
    14401 ttgagagcct gaatatgtta aaaaaacttc tctttccgtt agtcgctctg tttatgctgg
    14461 caggatgcgc cacaccgccg acgaccattg acgtcgcgcc gaagatcacc ttgccacagc
    14521 aggacccgag cctgatgggc gtcaccgtta gcattaccgg cgcggaccaa cgccaggatc
    14581 aagcgttagc gaaagtcacg cgtaacaacc agttggtaac gttaaccgcc tcccgcgatt
    14641 tacgcttcct gttacaagaa gtcctggaaa aacagatgac ggcgcggggc tatatgatcg
    14701 ggcctaacgg cgcggttaat ctgcagatta ttgttaacca actgtatgct gatgtttccc
    14761 agggcagcgt gcgctacaac atcgcgacca aagcggatat cgcgattatt gcgaccgcgg
    14821 caaatggcaa caagatgacc aaaaactatc gcgccaacta ctctattgaa ggggcgttcc
    14881 aggcctctaa ccagaatatt gccgacgcgg tgaacagcgt tctgaccgat accattgctg
    14941 atatgtctca ggacaccagc attcacgatt ttatcaagca aaacgcccgt taatagcaac
    15001 aacaagaccc ggcagaagcc gggtctgtag atgcctatgt caagtcaata tttacgtatt
    15061 ttccagcaac cgcgttcagc cattctgctg atattgggtt ttgcctccgg tctcccgctg
    15121 gcgctcactt ccggtacgct acaggcgtgg atgaccgtcg agaatatcga tcttaaaacg
    15181 attggcttct tctcgctggt tggtcaggcc tatgtgttta agtttctctg gtctccgctg
    15241 atggaccgct acacgccgcc ttttttaggt cgacgtcgcg gttggttact cgccacccaa
    15301 ctgttgttac tggcggcgat tgcggcgatg ggctttcttg aacccggcac gcagctacgc
    15361 tggatggcgg cgctggcggt ggtgattgct ttttgctccg cctcgcagga tatcgtgttc
    15421 gacgcctgga aaaccgatgt gttacccgca gaagaacgcg gcgctggcgc ggcaatcagc
    15481 gtgcttggct accggttggg gatgctggtt tccggcggac tggcgctatg gctggccgat
    15541 cgctggctcg gctggcaggg catgtactgg ctgatggcgg cattgttgat cccctgcatt
    15601 atcgccacct tactggcgcc ggaaccgacc gatactatcc cctccccgaa atcgctggaa
    15661 caggccgtcg tcgcgccgct acgcgatttc tttggccgta acaacgcctg gctgatttta
    15721 ctgctcattg tgctttataa actgggtgac gccttcgcca tgagcctgac caccaccttt
    15781 ttgattcgcg gcgtcggctt tgacgccggc gaagtcggtg tggtcaataa aacgttgggc
    15841 ctgctggcga cgatcgtcgg cgcgttatac ggcggcatat taatgcagcg tctttcgctg
    15901 tttcgcgcgc tgctgatttt cggcattttg caaggcgcgt ccaacgccgg ttactggttg
    15961 ctctccatta ccgataaaaa catgttcagc atgggcgcgg cggtcttttt cgaaaatctg
    16021 tgcggcggga tgggtactgc cgcctttgtc gccttattaa tgacgctatg taataagtcg
    16081 ttttccgcaa cacagtttgc cctactgtcg gccctctccg cagtaggccg ggtttatgtt
    16141 ggtcctgtag cgggctggtt cgttgaagcg cacggctggc cgacattcta cctcttctcg
    16201 gttgtcgccg ccgttcccgg gctgttactg ttgctggtct gtcggcaaac gctggaatat
    16261 agctggcaga gcgagcgttt cattccccgc acgcaatacc gtggcaccta caatttcgcg
    16321 ctttcaatcc tgctcgcggg cgtcgctttg ctggcggtgt gggtactcct gctgaccatg
    16381 aacgcgttgg attacactaa cttttcattc ctgcccgaat tgcttgagac tgcggtagc
//
LOCUS       DAJVBX010000097        16367 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.097, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000097 DAJVBX010000000
VERSION     DAJVBX010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 16367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16367
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.097"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(12..1481)
                     /locus_tag="OPV72_002615"
     CDS             complement(12..1481)
                     /locus_tag="OPV72_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HCR9914874.1"
                     /translation="MKKYLAFAVTLLGMGKVIACTTLLVGNQASADGSFIIARNEDGS
                     ANNAKHKVIHPVAFHQQGEYKAHRNNFSWPLPETAMRYTAIHDFDTNDNAMGEAGFNS
                     AGVGMSATETIYNGRAALAADPYVTKTGITEDAIESVILPVAQSARQGAKLLGDIIEQ
                     KGAGEGFGVAFIDSKEIWYLETGSGHQWLAVRLPADSYFVSANQGRLRHYDPNDNANY
                     MASPTLVSFAKKQGLYDPARGEFDFHQAYSQDNKNDTTYNYPRVWTLQHQFNPHLDTV
                     VSEGETFSVFLTPITKISVAAVKNALRNHYQGTSHDPYASHNPQEPWRPISVFRTQES
                     HILQVRPKLPQAIGNVEYIAYGMPSLSVYLPYYQGMRHYQPGDDKGTDRASNDSTYWT
                     FRTLQTLVMQDYNTFAPDVQHAWKTFEQQTAKQQYKMEQSYLRLYASHPKEAQRLLQN
                     FEDKTMQNAQTLARRLTNNIITTMTYRTDMKYHFSSTQP"
     gene            complement(1654..3018)
                     /locus_tag="OPV72_002616"
     CDS             complement(1654..3018)
                     /locus_tag="OPV72_002616"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_447527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal sensor histidine kinase"
                     /protein_id="HCR9914875.1"
                     /translation="MVKLSMTLRLTISFIAILILACTGISWTLYNALSKELTYRDDMT
                     LINRAAQMQQLLLDGARPENLPLYFNRMVDTKQDILLIHSATGHNVAINHSGIPDQRF
                     NEIPLAKNITRETLFRQAVQGTELTAVRVNARSGDNPLTLTIARLATERRQMLAQYRR
                     NSLLISLIAILVCSALSPLVIRNGLRAITSLSRLTAATDSGTLRQPLAEQALPVELRP
                     LGQALNTMRQKLSDDFERLNQFADDLAHELRTPVNILLGKNQVMLSQERSAEEYQQAL
                     VDNIEELEGLSRLTENILFLARAEHQNIAVKKQPVSLNALVENMLDYLSPLAEEKHIC
                     FINQCQGTVWADEILLQRVLSNLLTNAIRYSDENAVIRIESAYDDNVAEIRVANPGSP
                     TADADKLFRRFWRGDNARYTAGFGLGLSLVNAIALLHGGSASYRYADEHNIFSVRLPD
                     SGDS"
     gene            complement(3011..3691)
                     /gene="hprR"
                     /locus_tag="OPV72_002617"
     CDS             complement(3011..3691)
                     /gene="hprR"
                     /locus_tag="OPV72_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor HprR"
                     /protein_id="HCR9914876.1"
                     /translation="MKILLIEDNQKTIEWVRQGLTEAGYVVDYACDGRDGLHLALQEH
                     YSLIILDIMLPGLDGWQVLRALRTAYQPPVICLTARDSVEDRVKGLEAGANDYLVKPF
                     SFAELLARVRAQLRQHVPVFTRLTINGLDMDATKQSVLRNGKPISLTRKEFLLLWLLA
                     SRAGEIVPRTAIASEVWGINFDSETNTVDVAIRRLRAKVDDPFEKKLIMTVQGMGYRL
                     QAETSQNG"
     gene            3827..4237
                     /gene="hiuH"
                     /locus_tag="OPV72_002618"
     CDS             3827..4237
                     /gene="hiuH"
                     /locus_tag="OPV72_002618"
                     /EC_number="3.5.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyisourate hydrolase"
                     /protein_id="HCR9914877.1"
                     /translation="MKRYILATAIASLVAAPAMALAAGSNILSVHILDQQTGKPAPGV
                     EVVLEQKKDNGWTQLNTGHTDQDGRIKALWPEKAAAPGDYRVIFKTGQYFESKKLDTF
                     FPEIPVEFHISKTNEHYHVPLLLSQYGYSTYRGS"
     gene            complement(4570..5082)
                     /locus_tag="OPV72_002619"
     CDS             complement(4570..5082)
                     /locus_tag="OPV72_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate 3-monooxygenase reductase
                     subunit"
                     /protein_id="HCR9914878.1"
                     /translation="MQVDEQRLRFRDAMASLAAAVNIVTTAGHAGRCGITATAVCSVT
                     DTPPSVMVCINANSAMNPVFQGNGRLCINVLNHEQELMARHFAGMTGMAMEERFHQPC
                     WQNGPLGQPVLNGALASLEGEISEVQTIGTHLVYLVAIKNIILSQEGHGLIYFKRRFH
                     PVRLEMEAPV"
     gene            complement(5100..6461)
                     /gene="hpaB"
                     /locus_tag="OPV72_002620"
                     /pseudo
     CDS             complement(5100..6461)
                     /gene="hpaB"
                     /locus_tag="OPV72_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801462.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate 3-monooxygenase,
                     oxygenase component"
     gene            complement(6513..6953)
                     /gene="hpaR"
                     /locus_tag="OPV72_002621"
     CDS             complement(6513..6953)
                     /gene="hpaR"
                     /locus_tag="OPV72_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoprotocatechuate degradation operon regulator
                     HpaR"
                     /protein_id="HCR9914879.1"
                     /translation="MHDSLTIALLQAREAAMTYFRPIVKSHNLTDQQWRIVRILADSP
                     SMDFHELAFRTCILRPSLTGILTRMERDGLVLRLKPVNDQRKLYVMLTEQGQTLYARA
                     RSEVEEAYRKIEADFTPEKTQQLMLLLDDLIALGRQHPDSEAEA"
     gene            7228..8517
                     /locus_tag="OPV72_002622"
     CDS             7228..8517
                     /locus_tag="OPV72_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate degradation bifunctional
                     isomerase/decarboxylase"
                     /protein_id="HCR9914880.1"
                     /translation="MKGTVFAVALNHRSQLDAWQEAFSQPPYNAPPKTAVWFIKPRNT
                     VIRHGEPIPYPQGEKVLSGATVALIVGKTASRIRPEAAADYIAGYALANEVSLPEESF
                     YRPAIKAKCRDGFCPLGEMAPLSDVDNLTIITEINGREADHWNTADLQRSAAQLLSAL
                     SEFATLNPGDAILLGTPQNRVALRPGDRVRILAKGLPALENPVVAEDEFARHQTFTWP
                     LSATGTLFALGLNYADHASELAFTPPKEPLVFIKAPNTFTEHHQTSVRPNNVEYMHYE
                     AELVVVIGKTARKVSEAEAMEYVAGYTVCNDYAIRDYLENYYRPNLRVKSRDGLTPIG
                     PWIVDKEAVSDPHNLTLRTFVNGELRQEGTTADLIFSIPFLISYLSEFMTLQPGDMIA
                     TGTPKGLSDVVPGDEVVVEVEGVGRLVNRIVSEESAK"
     gene            8514..9979
                     /gene="hpaE"
                     /locus_tag="OPV72_002623"
                     /pseudo
     CDS             8514..9979
                     /gene="hpaE"
                     /locus_tag="OPV72_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460075.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="5-carboxymethyl-2-hydroxymuconate semialdehyde
                     dehydrogenase"
     gene            9981..10832
                     /gene="hpaD"
                     /locus_tag="OPV72_002624"
     CDS             9981..10832
                     /gene="hpaD"
                     /locus_tag="OPV72_002624"
                     /EC_number="1.13.11.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3,4-dihydroxyphenylacetate 2,3-dioxygenase"
                     /protein_id="HCR9914881.1"
                     /translation="MGKLALAAKITHVPSMYLSELPGKNHGCRQAAIDGHIEIGKRCR
                     EMGVDTIIVFDTHWLVNSAYHINCADHFQGVYTSNELPHFIRDMTYDYDGNPALGHLI
                     ADEAVKLGVRAKAHNIPSLKLEYGTLVPMRYMNSDKHFKVVSISAFCTVHDFADSRKL
                     GEAILKAIEKYDGTVAVFASGSLSHRFIDDQRAEEGMNSYTREFDHQMDERVVKLWRE
                     GKFKEFCTMLPEYADYCYGEGNMHDTVMLLGMLGWDKYDGKVEFITDLFASSGTGQVN
                     AVFPLPA"
     gene            10842..11222
                     /locus_tag="OPV72_002625"
     CDS             10842..11222
                     /locus_tag="OPV72_002625"
                     /EC_number="5.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-carboxymethyl-2-hydroxymuconate
                     Delta-isomerase"
                     /protein_id="HCR9914882.1"
                     /translation="MPHFIAECTENIREQADLPSLFSKVNEALAATGIFPIGGIRSRA
                     HWLDTWQMADGKHDYAFVHMTLKIGAGRSLESRQEVGEMLFGLIKAHFADLMENRYLA
                     LSFEIAELHPTLNYKQNNVHALFK"
     gene            11366..12169
                     /gene="hpaH"
                     /locus_tag="OPV72_002626"
     CDS             11366..12169
                     /gene="hpaH"
                     /locus_tag="OPV72_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo-hepta-3-ene-1,7-dioic acid hydratase"
                     /protein_id="HCR9914883.1"
                     /translation="MLDKQTHTLIAQRLNQAEKQREQIRAVSLDYPNITIEDAYAVQR
                     EWVNIKIAEGRTLKGHKIGLTSKAMQASSQISEPDYGALLDDMFFHDGGDIPTDRFIV
                     PRIEVELAFVLAKPLRGPHCTLFDVYNATDYVIPALELIDARSHNIDPETQRPRKVFD
                     TISDNAANAGVILGGRPIKPDELDLRWISALLYRNGVIEETGVAAGVLNHPANGVAWL
                     ANKLAPYDVQLEAGQIILGGSFTRPVPARKGDTFHVDYGNMGAISCRFV"
     gene            12180..12971
                     /gene="hpaI"
                     /locus_tag="OPV72_002627"
     CDS             12180..12971
                     /gene="hpaI"
                     /locus_tag="OPV72_002627"
                     /EC_number="4.1.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-2-oxoheptanedioate aldolase"
                     /protein_id="HCR9914884.1"
                     /translation="MKNAFKDALKAGRPQIGLWLGLANSYSAELLAGAGFDWLLIDGE
                     HAPNNVQTVLTQLQAIAPYPSQPVVRPSWNDPVQIKQLLDVGAQTLLIPMVQNADEAR
                     NAVAATRYPPAGIRGVGSALARASRWNRIPDYLHQANDAMCVLVQIETREAMSNLASI
                     LDVDGIDGVFIGPADLSADMGFAGNPQHPEVQAAIENAIVQIRAAGKAPGILMANEAL
                     AKRYLELGALFVAVGVDTTLLARGAEALAARFGAEKKLSGASGVY"
     gene            13043..14419
                     /gene="hpaX"
                     /locus_tag="OPV72_002628"
     CDS             13043..14419
                     /gene="hpaX"
                     /locus_tag="OPV72_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate permease"
                     /protein_id="HCR9914885.1"
                     /translation="MSDTSSALPESPESVGSHNALSTGQQTVINKLFRRLIVFLFVLF
                     IFSFLDRINIGFAGLTMGQDLGLSATMFGLATTLFYATYVIFGIPSNVMLSIVGARRW
                     IATIMVLWGIASTATMFAVGPKSLYVLRMLVGITEAGFLPGILLYLTYWFPAFFRARA
                     NALFMIAMPATTALGSIVSGYILSLDGIFNLHGWQWLFLLEGFPSVLLGIMVWFYLDD
                     TPAKAKWLTAEDKKCLQEMMDNDRLTLVQPEGAISHNAMQQRSLWREVFTPIVLMYTL
                     AYFCLTNTLSAISIWTPQILKSFNEGSSNITIGLLAAIPQICTVLGMIYWSRHSDKHQ
                     ERKHHTALPFLFAAAGWLLASATDRNLIQLLGIVMASTGSFSAMAIFWTTPDQSISLR
                     ARAIGIAVINATGNIGSALSPVMIGWLKDITGSFNSGLWFVASLLVVGAAIIWLIPMK
                     ASRPRATP"
     gene            14429..15325
                     /gene="hpaA"
                     /locus_tag="OPV72_002629"
     CDS             14429..15325
                     /gene="hpaA"
                     /locus_tag="OPV72_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate catabolism regulatory
                     protein HpaA"
                     /protein_id="HCR9914886.1"
                     /translation="MCQRAIANIDISKEYDESMGSNDVHYQSFARMADFFGRDMQAHR
                     HDQFFQMHFLDTGQIELQLDDHRYSVQAPLFVLTPPSVPHAFITESDSDGHVLTVREE
                     LVWPLLEVLYPGTREAFGLPGICLSLADKLNELAALKHYWQLIERESTEQLAGCEHTL
                     VLLAQAVFTLLLRNAKLDDHAATGMRGELKLFQRFTLLIDNHFHQHWTVPDYACELHI
                     TESRLTDICRRFANRPPKRLIFDRQLREAKRLLLFSDNAVNEIAWQLGFKDPAYFARF
                     FNRLAGCSPSQFRQREVPSFLN"
     gene            15339..16277
                     /locus_tag="OPV72_002630"
     CDS             15339..16277
                     /locus_tag="OPV72_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCR9914887.1"
                     /translation="MMKKSVAMLAVCMLAQSHLAIAAGAPAPQEINIVLLGTKGGPSL
                     LNTARLPQATALTIGDKIWLIDAGYGASLQLVKNGIPLRNINTILLTHLHSDHILDYP
                     SLLMNAWASGLKDHTIQVYGPPGTQAMTKASWKVFDRDITLRMEEEGKPDPRNLVKAT
                     DIGQGVIYKDELVTISALKVPHSPFPDGEAFAYRFDTQGKRIVFSGDTSWFPPLATFA
                     QGADILVHEAVHVPSVAKLANSIGNGKTLAEAIASHHTTIEDVGKIAREAHVKKLVLS
                     HLVPATVADDVWQQEAMKNYPGPVIVGHDNMTISVP"
BASE COUNT         3787 a         4312 c         4428 g         3840 t
ORIGIN      
        1 tgtcattaaa tttatggctg cgtacttgaa aagtgatatt tcatatctgt gcggtaagtc
       61 attgtcgtaa taatattatt ggtcaggcga cgggcgagcg tctgcgcatt ttgcatcgtt
      121 ttatcttcaa aattttgcag taagcgttgt gcttctttcg gatgcgacgc atataatctc
      181 agatagctct gctccatctt atactgttgc ttagctgttt gctgttcaaa tgttttccag
      241 gcatgttgca catctggcgc aaacgtattg tagtcttgca taaccagtgt ttgcagcgtg
      301 cggaatgtcc agtaggtaga gtcgttgctc gcccgatcgg ttcctttatc atctccgggt
      361 tgataatgac gcatcccctg gtaatagggg agatagacgc taagagatgg cattccatag
      421 gcgatgtatt ctacgttgcc gatagcctgc ggtaatttcg gtctgacctg taaaatatgt
      481 gactcctggg tacgaaaaac ggatataggt cgccatggtt cttgtggatt atgactggca
      541 taagggtcgt gcgacgttcc ctgatagtga ttgcgtaacg cgttttttac tgccgccacg
      601 ctgatcttcg ttattggcgt taaaaaaaca gaaaatgttt ccccttcgct aacgaccgta
      661 tccagatgcg gattaaactg gtgttgtagc gtccagacgc gcggataatt ataggtggta
      721 tcgtttttgt tatcctgcga ataggcttga tgaaagtcga attcgccgcg ggccggatca
      781 tataatccct gctttttcgc aaagcttact aacgttggtg acgccatata attcgcgtta
      841 tcattcggat cgtaatggcg taaacgtccc tgattggcgg aaacgaaata gctatctgcc
      901 ggaagtcgta ctgccagcca ttgatgtccg cttcccgtct ccagatacca tatctctttg
      961 ctatcaataa acgcgacgcc gaaaccttcg cccgcgcctt tttgttcaat aatatctccc
     1021 agtaatttgg cgccctgacg cgccgattgc gccactggca ggatcacgga ctcaatggcg
     1081 tcttccgtga ttcccgtttt tgtcacgtaa ggatcggcag ccagcgccgc tctgccgttg
     1141 taaatggttt ccgttgcgct cattccgacg cccgccgaat tgaaaccggc ttcacccatg
     1201 gcgttatcgt tagtatcaaa gtcatgaatc gccgtatagc gcatcgctgt ctccggaagc
     1261 ggccagctaa aattgttgcg atgtgcttta tactcgcctt gttgatgaaa cgcgacggga
     1321 tgaataacct tatgcttggc gttatttgcc gagccatcct cgttgcgcgc gataataaag
     1381 gagccgtcag ccgaagcctg attgcctacc aaaagggtag tacaggcgat gactttaccc
     1441 atacccagca gcgtaacggc gaaagcaaga tactttttca taaaggttcc cactgaataa
     1501 cgcgttatgg gatgaattga ccctggattg gaaaccgaga aagtgatcga gccagcaata
     1561 ttctttaccg gcatccttta ttttcttttt attgaggttg tattgataac cacagccctg
     1621 tggcagggaa ggggaacaga acctgtactg accttagcta tcaccgctat caggcagacg
     1681 aaccgaaaag atattatgtt catcggcata gcggtaagat gccgagccac cgtgcaatag
     1741 ggcaatcgcg ttaactaacg ataaccccag gccgaaaccg gcagtgtagc gggcattatc
     1801 tcctcgccaa aaacgccgga aaagcttatc cgcatcggcg gtggggctgc ccggattagc
     1861 gacccgaatt tctgcaacgt tatcatcata agcgctttca atacgtatca cggcgttttc
     1921 atcagaataa cggatggcat tcgtcagcag gtttgagagc actctttgta ataatatttc
     1981 gtcagcccat accgttccct gacattgatt tataaaacag atgtgcttct cttcggcaag
     2041 ggggctaaga taatccagca tattttcgac cagcgcattg agcgaaacag gctgtttttt
     2101 taccgctata ttctggtgct ccgcgcgtgc cagaaagaga atattttctg tcagtcgcga
     2161 cagtccctcc agctcttcaa tattatcgac aagggcttgt tgatactctt cggcgctgcg
     2221 ttcctgactc agcataacct gattcttccc cagtaaaata ttaaccggcg tgcgcagctc
     2281 atgcgccaga tcgtcggcaa attggttcag gcgttcaaaa tcgtcggaaa gcttctggcg
     2341 catggtattt agcgcttgcc caagcggcct gagctcgacg ggtaacgcct gttccgccag
     2401 cggctggcga agtgtgccgc tatctgtcgc cgcggtgagt cggctgagcg acgtaatggc
     2461 ccgcagcccg tttctgatga ctaatggact gagcgccgaa cagacgagga tcgcgataag
     2521 gctaatcagc aaactgttgc ggcgatattg cgccagcatt tgccgccttt ccgtcgccag
     2581 cctggcaata gtaagggtca gcgggttatc gccgcttctg gcgtttactc gtaccgcggt
     2641 cagctccgtg ccttgtaccg cctggcgaaa taaggtttcg cgggtgatgt ttttagccag
     2701 cggaatctcg ttaaagcgtt ggtcggggat gccgctatga ttaatcgcaa cattatggcc
     2761 tgttgctgag tggatcaata agatatcctg cttcgtatcc accatccgat tgaaatagag
     2821 cggcagattt tccggcctgg cgccatccag taacagttgc tgcatttgcg ccgcccgatt
     2881 tattagcgtc atatcatccc gatacgttaa ttctttgctc agcgcgttat agagcgtcca
     2941 gctaatgccg gtacaggcga ggataagtat ggcgataaaa gaaattgtca ggcgcagcgt
     3001 cattgataac ttaaccattc tgcgacgttt ccgcctgtaa tcgataaccc atcccctgga
     3061 cggtcataat gagcttcttt tcaaatggat cgtctacttt ggcgcgcagc cgacgaatcg
     3121 cgacatcaac ggtgttggtt tcactatcaa agttaattcc ccaaacttcg ctggcgatcg
     3181 cggttcgggg cacgatttcc cctgcccggg acgccagtaa ccagaggagc aggaattctt
     3241 tgcgggtcag ggaaatcggt ttgccatttc gtaacaccga ttgctttgtg gcatccatgt
     3301 ccagaccatt gatcgtcagt cgggtaaaga ccgggacatg ctgtctgagt tgagctctca
     3361 cccgggccag cagttcggcg aaggaaaaag gcttaacaag gtaatcatta gcgcccgcct
     3421 caagaccttt gacgcgatcc tcaaccgagt cgcgcgccgt caggcaaata acagggggct
     3481 gatatgcagt gcgcaacgcg cgtaaaacct gccatccatc aagccccggc agcataatat
     3541 caagaataat caatgaataa tgttcctgaa gggctaggtg taatccgtct cgtccatcac
     3601 aggcataatc aaccacatag cctgcctccg tgagtccctg acgtacccac tcaatggttt
     3661 tctggttatc ttcaatcaat aaaatcttca tcaacgcagt atgccatagg cttgttagcg
     3721 aatccgtaaa tctccaacaa gatgacataa ttgtcatgtc cgtgtaaggt taatcctgga
     3781 cgcgccagat atattttcct gcatcaatac cgtaaaggag tgaagcatga aacgatatat
     3841 actggctacc gcgatagcgt ctcttgttgc agccccggca atggcgctgg ccgctggcag
     3901 caatattctc agcgtacata ttctcgatca gcaaacaggc aaaccagcgc ccggcgtgga
     3961 ggtggtactg gagcagaaaa aggataacgg atggacgcaa ttaaacaccg ggcataccga
     4021 ccaggatgga cgaattaaag cactgtggcc cgaaaaagct gccgcgccgg gggattatcg
     4081 cgttattttt aaaaccggcc agtattttga aagtaaaaaa ctggacacgt ttttcccgga
     4141 gattcccgtc gagtttcata tcagcaaaac gaatgagcac tatcatgtgc cgctgttatt
     4201 aagtcagtat ggttattcaa cctatcgcgg gagctaattt agagcctatc ctattagggc
     4261 tattttactt gccattttgg tcctgggcag tgctcgccaa aacgcgttag cgttttgaac
     4321 gccgcttgcg gcggcccgaa gggcgagcgt agcgagtcaa acctcacgta caacgtgtac
     4381 gctccggttt ttgcgcgctg tccgtgtcca aacaggctgc gccaataacg cctggtggga
     4441 caggctctta gattttatta atcgccggga tttatggcga gcaaacatcg cggcgggaat
     4501 aaaaatcttc agcgtatcga ctctcctccc acaagcggtg gttatcccgc ttgtgggtat
     4561 gagtgacggt taaacaggcg cttccatctc aagtctgacc ggatgaaaac ggcgtttgaa
     4621 ataaatcagg ccatgcccct cctggctaag aataatattt ttgatcgcca ccagatacac
     4681 cagatgcgtg ccaatggttt gtacctcgct gatctcgcct tcaagactgg ccagcgcgcc
     4741 gttaagtacc ggctggccca gcggcccgtt ttgccaacat ggctggtgaa aacgctcctc
     4801 catcgccatc cccgtcatac cggcaaagtg gcgcgccatc agctcctgct catggttaag
     4861 tacattaatg cacagcctgc cgttgccctg aaaaacgggg ttcatggcgc tattggcatt
     4921 aatacatacc atcacggagg gcggcgtatc agtgactgag caaaccgctg ttgcggtgat
     4981 accgcagcgt ccggcgtgac ccgccgtggt tacgatgttg accgctgccg ccagacttgc
     5041 catcgcatcg cgaaaacgca gacgttgttc atctacttgc atgagaacct cctgccgcgt
     5101 tatttcagca gcttatccag ttgattgatg tcgtcgttat tgtgcaaatg cgaaaccgtc
     5161 cagccattct gatcgtattc ggagaggcag cgatcgacca ttgccatcat cttatccata
     5221 ttgccggagc tctgggcctg acgcagacac tgcagacgaa tttcatcctg gctgcccgag
     5281 tagttaatct cgtacagctc atggcgaccg ccaaactcgc tgccgatggc atcccacatc
     5341 aatttaagaa ttttgatacg ttcaacatgg tccattccgt tagagccgcg tacgtatttc
     5401 gccaggtact ggtcgatttg cggattattc agatcgcggg cgctggaagg caggtaaatc
     5461 aggccgctgg taacgttacg ttcaataata tttttaattt tcgcgtaggc cattggggcc
     5521 atcacacgat aggtttgcag cgcggcgtgg tccggtagcc aggcgccgtt tacccacggg
     5581 gttgcttcag aacacataga atcgctcaat gcccagaaca tattgcgcca ggccacgact
     5641 tcgccgagat cggcctgcac gccccggaac tctacggtac ccgtacattc gagcgatttt
     5701 ttcagcagcg cggtaatgaa atcaagtttt accgccagac gaacacaggc ttgcagtgga
     5761 tacatacggg caaagccgcc ttccatcgtc cagcgacgac aacgatcgaa atcacggtaa
     5821 attaatacgt tttcccacgg gatcagcacc ttgtccatca ccagaatggc atcgttttca
     5881 tcaaaacggc tggagagggg ataatcaaac ggcgagcccg tcgcgcccgc gaccatttca
     5941 tacgaggcgc gcgaaataag ttttacgcct tcggcatcca ttggcgcgac aaacatcaga
     6001 gcaaaatccg ggttttcgcc catcacctgg gctgagccga aaccaatcat gttgtagtga
     6061 gtcagggcgg agttagtggc gacaactttc gccccgctga caataatccc ggcgtccgtc
     6121 tctttctcca gcttgatata gacgtctttc acttcgtcgg caggtttgtg gcggtcaatg
     6181 ggcgggttga cgattgcatg gttaaagtac aggccggtct cctgaatacg ggtgtaccag
     6241 ttacgggcgt tctgctcaaa ctggccgtag aaggctgggt tagcgcccag agcgcagcca
     6301 aaggcggctt tgtaatccgg tgtgcgtccc atccagccgt aactcaggcg tgaccactcg
     6361 gcgatagcat cacgctgttg gcgcagatcg tctgcgcttt tcgccacgcg gaaaaattta
     6421 tgcgtataac cgccgctgcc ggtatcggta ttccagcaca gggtgtaagc gggaggggat
     6481 tcccgtgtcg gcggcgtggg aaggtaagaa tactatgctt ccgcttcgct atcaggatgc
     6541 tggcgcccca gagcaataag atcgtccagc agcagcatca attgctgtgt tttttcgggc
     6601 gtgaaatcgg cctcaatttt tcgataagcc tcttctacct cgctccgggc acgggcgtac
     6661 aacgtttgtc cctgctccgt caacatgaca tataacttac gctgatcgtt aaccggcttg
     6721 agtcgcaaca ccagtccgtc tcgctccatg cgcgtcaata ttccggtcag acttggacgc
     6781 aaaatacagg tacgaaaggc cagctcgtga aaatccatag aggggctatc ggccaggatt
     6841 cgcacaatgc gccattgctg gtcggtcaga ttgtggcttt taacgatggg gcggaaatag
     6901 gtcattgccg cttcgcgcgc ctgaagcaag gcgatggtta atgaatcatg cataagcgtt
     6961 tctcttttgc agaattatta atacctgaat aatcgtgttt accgatgtga gctatgacat
     7021 ctgttttatg tccaaagttt aacagaaaca aggggtttta tttaactatt tgatatatat
     7081 gtatttaata ataaatttgt gaaaatattg ttaatcacat cataaatact ttacttaagc
     7141 ttgctaaatg tacagcgaaa gcataaatct aatcattaat atgttaatga aatcacagcc
     7201 cgttaaatcg gcctgaggag tttatgtatg aagggtactg ttttcgccgt tgcgttaaac
     7261 catcgcagcc agcttgatgc ctggcaagag gctttctctc agcctcccta taatgcgccg
     7321 cctaaaaccg cagtgtggtt catcaagccg cgtaatacgg tgattcgtca cggcgaaccc
     7381 attccttatc cgcagggaga aaaggtactg agcggcgcga cagtggcgct cattgtgggg
     7441 aaaaccgcca gccggatacg ccctgaagcg gcggcggact atatcgccgg gtatgcgctg
     7501 gctaacgagg tcagcctgcc ggaagagagc ttttatcgcc cggcgattaa agcgaaatgt
     7561 cgcgatggct tttgcccgct gggtgaaatg gcgccgctga gtgatgtgga taatctcacc
     7621 attatcactg aaatcaacgg acgagaagcg gaccactgga atactgccga tttacagcgt
     7681 agcgccgcac aactgcttag cgcgttaagt gagttcgcta cacttaaccc tggcgatgcg
     7741 atcttacttg gtacgccgca gaatcgcgtt gcgctgcgtc ccggcgatcg ggtgcgtatt
     7801 ctggcgaaag gtttacccgc gctggaaaat ccggttgtcg cagaagatga attcgcccgc
     7861 caccagacgt ttacgtggcc gctgtcagcg acgggaacgt tatttgcgct ggggttgaac
     7921 tacgccgatc acgccagcga gctggcattt acgccgccga aagagccgct ggtatttatc
     7981 aaagcgccaa acacctttac cgaacatcac caaacgtcgg tgcgcccgaa caacgtcgaa
     8041 tatatgcact acgaagccga gctggtcgtg gtgattggca aaacggcgcg taaggtgagc
     8101 gaagccgaag ccatggagta tgtggccggt tacaccgtct gtaacgacta cgcgatccgc
     8161 gactatctgg aaaactacta ccgtccgaat ctgcgggtaa aaagccgcga cggcctgacg
     8221 ccgataggcc cgtggattgt ggataaagag gcggtttctg atccgcacaa cctgacgtta
     8281 cgcacctttg tcaacggtga gctgcggcag gaagggacga ccgccgatct gatcttcagc
     8341 atcccgttcc tgatttctta tctgagcgaa tttatgacgt tgcaaccggg cgacatgatt
     8401 gccaccggta cgccgaaagg gctgtccgat gtggtgccgg gggatgaagt tgtcgttgaa
     8461 gtagaaggcg tgggtcgcct ggttaaccga atcgtcagtg aggagagcgc aaaatgaaga
     8521 aaataaatca ttgaattaac ggcaaaaacg ttgcaggtaa cgactacttc cagaccacta
     8581 acccggcgac cggtgatgtg ctggcggaag tagcctccgg cggtgaagca gaagtgaacc
     8641 aggctgtcgc ggcggcaaaa gaggcgttcc cgaaatgggc caacctgccg atgaaagagc
     8701 gcgcgcgcct gatgcgccgc cttggcgacc tgattgacca gcatgtgccg gaaatcgcgg
     8761 cgatggaaac cgccgacacc ggcctgccta ttcaccagac taaaacgtgc tgatcccgcg
     8821 cgcctcgcat aacttcgaat tcttcgccga agtgtgccag cagatgaacg gcaagaccta
     8881 tccggttgac gataaaatgc tcaattatac gctggtgcag cccgtcggcg tctgcgcgct
     8941 ggtgtcgccg tggaacgtgc cgtttatgac cgcgacttgg aaagttgcgc cgtgcctggc
     9001 gctgggtaac accgcggtgc tcaaaatgtc cgagctgtcg ccgctgactg ccgacaggct
     9061 gggcgagctg gcactggagg caggaattcc ggcaggcgtg ctgaacgtgg tgcagggcta
     9121 cggcgcgacg gcgggcgatg cgctggtacg ccaccatgac gtgcgtgcgg tgtcgtttac
     9181 cggcggtacc gccaccggtc gcaatatcat gaaaaatgcc gggctgaaaa aatactcgat
     9241 ggagctgggc ggcaaatcgc cggtgctgat ttttgaagac gccgacattg agcgcgcgct
     9301 ggacgccgcg ctgttcacca tcttctcgat caacggcgaa cgctgcaccg ctgggtcgcg
     9361 catctttatc cagcagagca tttaccctga gttcgtgaag cgctttgccg aacgcgcgaa
     9421 tcgcctgcgt gtcggcgatc cgaccgaccc gaacacccag gtcggcgcgc tgattagcca
     9481 acagcactgg gagaaagtct ccggttatat ccgcctcggc attgaagagg gggcaacgct
     9541 gctggcgggc ggtgcggaaa aacccactga cctgcctgcg catctgaaag gcggtaactt
     9601 cctgcgccca accgtgctgg ccgatgtcga caaccgtatg cgcgttgcgc aggaagagat
     9661 ctttgggccg gtcgcctgcc tgctgccatt caaagacgaa gcggaagggt tacgtttggc
     9721 gaacgatgtg gaatacggtc tggcctctta tatctggacc caggacgtga gcaaagtgtt
     9781 gcgcctggcg cgtgggattg aagccggcat ggtcttcgtc aacacccaga acgtccgcga
     9841 cctgcgccag ccgttcggcg gcgtgaaagc ctccggtacc gggcgcgaag gcggcgaata
     9901 tagcttcgaa gtgtttgcgg aaatgaaaaa cgtctgcatc tcaatgggcg accatcctat
     9961 cccaaaatgg ggagtttgat atgggcaagt tagcgttagc agcaaaaatt acccacgtgc
    10021 cgtcgatgta tctttctgaa ctgccaggaa aaaatcacgg ttgtcgtcag gcagccattg
    10081 atgggcatat tgaaattggc aagcgttgcc gcgaaatggg cgttgacacc attatcgtat
    10141 tcgacaccca ctggctggtg aatagcgctt accacattaa ttgtgccgac catttccagg
    10201 gcgtctatac cagcaacgaa ttgccgcact ttattcgcga catgacctat gactatgacg
    10261 gtaatccggc gctcggccat ctgatcgccg acgaggcggt caaactgggc gtgcgcgcca
    10321 aagcgcacaa catcccgagc ctgaagctgg agtatggcac gctggtgccg atgcgctaca
    10381 tgaacagcga caagcacttc aaagtggtct ccatctcggc gttctgcact gtgcatgatt
    10441 ttgccgacag ccgcaaactg ggcgaagcca ttctcaaggc gattgagaaa tatgacggta
    10501 ccgtagcggt attcgccagt ggttctctgt cgcaccgttt tattgacgac caacgggcgg
    10561 aagaggggat gaacagctac acccgcgagt tcgatcatca aatggacgag cgcgtggtca
    10621 agctgtggcg cgaaggcaaa ttcaaggagt tttgcaccat gttgccggag tacgccgact
    10681 actgctacgg cgaaggcaac atgcacgaca cggtcatgct actgggaatg ctggggtggg
    10741 acaaatacga cggcaaggtg gagttcatca ccgacctgtt cgccagctcc ggtaccggcc
    10801 aggtaaacgc tgttttcccg ctgcctgcgt aaggggggtt tatgccgcac tttattgctg
    10861 aatgtactga aaatattcgc gagcaggctg atttaccaag cctgttcagc aaggtaaacg
    10921 aggcgctggc cgccaccggg attttcccca tcggcggtat ccgcagtcgc gcccactggc
    10981 tggatacctg gcagatggct gacggtaagc atgattacgc gtttgtgcat atgacgctga
    11041 aaatcggcgc cgggcgcagc ctggagagcc gtcaggaagt cggcgaaatg ctgtttgggc
    11101 tgattaaagc ccacttcgcc gacctgatgg agaaccgcta tctggcgctg tcgtttgaga
    11161 ttgccgagtt acatccaacg ctcaattaca aacaaaacaa cgtacacgcg ttatttaaat
    11221 agcacactct ttcgcccggt ggcgctgcgc tgaccgggcc tacaaaaaaa cgatgcacga
    11281 agcagtaccg aaccgtaggc cgggtaagac gcacccgcgt cgccacccgg cgcagcagca
    11341 ccgaatgagg taacaggaag caactatgct cgataaacag acccataccc tgatcgctca
    11401 gcgacttaat caggctgaaa aacagcgtga acagattcgc gcagtgtcgc tggattatcc
    11461 caacatcact attgaagatg cctatgccgt acagcgtgaa tgggtcaata tcaagattgc
    11521 cgaagggcgc acgctcaaag gccacaaaat cggcctgacc tcaaaagcga tgcaggccag
    11581 ctcgcaaatc agcgaaccgg attacggcgc gctgcttgac gatatgttct tccatgacgg
    11641 cggagatatc cccaccgacc gttttatcgt cccgcgtatt gaagtggagc tggcgttcgt
    11701 gctggcgaaa ccgctgcgcg gccctcactg cacgctgttc gacgtctaca acgccacgga
    11761 ttatgtgatt ccggcgctgg aactgattga cgcccgcagc cacaacatcg acccggaaac
    11821 ccagcgcccg cgcaaagtgt tcgacaccat ttccgacaac gccgccaacg ccggggtgat
    11881 cctcggtggt cgccccatca aaccagacga gctggatctg cgctggatct ccgcgctgct
    11941 ctatcgcaac ggcgtgatcg aagaaaccgg cgtcgccgca ggcgtgctga atcatccggc
    12001 caacggcgtg gcgtggctgg cgaacaagct tgccccctac gatgtccagc ttgaagccgg
    12061 gcagatcatc ctcggcggct cgttcacccg cccggtgccg gcgcgcaagg gcgacacctt
    12121 ccatgtcgat tacggcaaca tgggcgcgat cagttgccgg tttgtgtaag gaaaaaacga
    12181 tgaaaaatgc tttcaaagac gcgttaaaag cggggcgccc gcaaatcggt ttgtggctgg
    12241 ggcttgccaa cagttacagc gctgaactgt tagcgggcgc cggcttcgac tggctactga
    12301 ttgacggtga acacgcgcca aacaacgtgc agacggtgtt gacccagttg caggcgattg
    12361 cgccttatcc cagccagccg gtggtgcgtc cgtcatggaa cgatccggta cagattaagc
    12421 aactgctcga cgtcggcgcg caaacgctgc tgataccgat ggtgcagaat gccgatgaag
    12481 cgcgaaacgc cgtggcggct acgcgttatc cgcctgccgg tattcgcggc gtgggcagcg
    12541 cgctggcgcg ggcatcgcgc tggaatcgca ttccggacta tctccaccag gccaacgacg
    12601 ccatgtgcgt actggtgcag attgaaacgc gtgaggcgat gagcaatctg gcgtcaattc
    12661 tcgacgtgga tggcattgac ggcgtgttta ttggcccggc ggatctcagc gccgatatgg
    12721 gctttgccgg caatccgcag cacccggaag tgcaggcggc gattgagaac gccatcgtgc
    12781 agatacgcgc ggcggggaaa gcgccgggga ttctgatggc caatgaagca ctggcgaaac
    12841 gttatctgga actgggggcg ctatttgtcg ccgtcggcgt tgacaccacg ctgctggcgc
    12901 gcggagcgga ggcgctggcg gcgcgctttg gcgcagaaaa aaaactgtcc ggtgcgtccg
    12961 gcgtctatta agcctgggcc ggtaagcgca gcgctaccgg gcaaccgtag taccctacaa
    13021 aattcccatc agaggaaaaa aaatgagcga cacatcatct gcacttccgg aaagccccga
    13081 gtctgtcggt tcgcacaacg cgctcagcac gggtcaacaa accgtcataa ataaactgtt
    13141 ccgccgactg atcgtatttt tattcgtgtt gtttatcttc tcgtttttag accgtatcaa
    13201 catcggtttt gccgggttga cgatggggca ggatctgggg ttaagcgcca ccatgtttgg
    13261 tcttgccacg acgctgtttt acgccaccta cgtcattttc ggcattccca gcaacgtgat
    13321 gttgagcatc gtcggcgccc gccgctggat tgcgaccatt atggtgctat ggggcattgc
    13381 atctaccgcc acgatgttcg cggtgggacc gaaaagcctg tatgtgctgc gaatgctggt
    13441 gggcattacc gaagcgggct ttttgccagg aatattgctc tatttaacct actggttccc
    13501 ggcatttttc cgcgcccgcg ccaacgcatt atttatgatt gccatgccgg ccactaccgc
    13561 gttggggtca attgtctccg gctatatttt atcgctggac ggcatattca atctgcatgg
    13621 atggcagtgg ttattcctgt tggaaggatt tccgtcagtt ttgttaggca ttatggtctg
    13681 gttttacctg gatgataccc cggcaaaagc caaatggctg acggcagagg ataaaaaatg
    13741 tttgcaggag atgatggata atgatcgcct gacgctggtt cagcctgagg gggccatcag
    13801 ccataacgcc atgcagcagc gtagcctgtg gcgcgaagta ttcacgccaa ttgtactgat
    13861 gtatacgctg gcctattttt gccttaccaa tacgcttagc gccattagta tctggacgcc
    13921 gcaaatcctg aaaagtttta atgaaggcag cagcaatatc accatcggcc tgctggcggc
    13981 gatcccgcag atttgtactg ttctgggcat gatttactgg agccgccatt cggacaaaca
    14041 tcaggagcgt aaacaccaca ctgcgttacc gttcctgttt gccgccgcgg gctggctgct
    14101 ggcgtcggcg accgaccgta acctgatcca gctcctgggg atcgtgatgg catccacggg
    14161 ttcctttagc gcgatggcga tcttctggac cacgccggat cagtcgatca gtttacgcgc
    14221 cagggcgata ggcattgcgg tcatcaatgc caccggcaat attggctccg cgctcagccc
    14281 ggttatgatt ggctggctaa aagatatcac tggtagcttc aatagcggac tctggtttgt
    14341 cgcttctctg ttagtcgtcg gcgccgccat tatctggctc attcccatga aagcatcgcg
    14401 tccgcgcgcc accccttgag gagaaactat gtgccaacgt gcgatcgcca atattgatat
    14461 cagcaaagag tatgacgaaa gcatgggcag taacgatgtg cattatcagt cgtttgctcg
    14521 tatggcggat ttctttggtc gtgatatgca ggcgcatcgc cacgaccagt tttttcaaat
    14581 gcactttctt gataccgggc agattgagct acagctcgac gatcatcgct attcggtgca
    14641 ggcgccgcta tttgtgctaa cgccgccctc ggtgccgcat gcttttatta ccgaatcgga
    14701 tagcgatggt catgttctga cggtacgcga agagctggtt tggccgctgc tggaagtgct
    14761 ttatcccggc accagagagg ccttcggcct gccgggaatc tgcctgtcgc tggcggataa
    14821 actcaacgag ctggcggcgc tcaaacatta ctggcagcta attgagcggg agtccacgga
    14881 acaactggct ggctgcgaac ataccttggt actactggcg caggcggtat ttaccttgct
    14941 gttgcgtaat gcgaagctgg acgatcatgc cgcaaccggg atgcgcggtg aactgaaact
    15001 ttttcagcgc tttaccctgt taattgacaa ccacttccat cagcactgga cggtgcccga
    15061 ttatgcctgt gagttgcata ttaccgaatc tcgtttgacc gatatttgcc gacgttttgc
    15121 taatcgcccg cctaaacgcc tgatttttga tcggcaatta cgcgaggcga aacgactgct
    15181 gcttttttcc gacaatgctg tcaacgagat cgcctggcaa ttaggtttta aagatccggc
    15241 ttatttcgcc cgtttcttta atcgccttgc tggctgttct ccttcgcagt ttcgccaacg
    15301 tgaagttcct tcttttctca actaagaaga gtaaaaacat gatgaaaaaa agcgtcgcta
    15361 tgctggcggt ttgtatgctg gcgcaaagcc accttgccat tgctgccggt gctcctgcgc
    15421 ctcaagagat caacattgtt ttactgggca ccaaaggcgg gccttctttg ctcaatacag
    15481 ccagactacc gcaagcgacg gcgctcacta tcggcgataa gatatggctg atagatgccg
    15541 gctacggcgc cagtctgcaa ctggtgaaaa atggcattcc actgcgcaac atcaatacta
    15601 ttttgctcac ccatctgcac agcgaccaca tactggatta tccttccttg ctgatgaatg
    15661 cctgggcaag tggcctgaaa gaccatacca tacaggttta tggcccgccg ggaacccagg
    15721 cgatgacgaa ggctagctgg aaggtctttg acagggatat cacgttacgc atggaagaag
    15781 aggggaaacc cgatccgcgc aacctggtta aggcgaccga tatcggccag ggcgtcatct
    15841 ataaagatga actggtcaca ataagcgcgc tgaaagtgcc tcattcccct ttcccggacg
    15901 gtgaagcgtt tgcttaccgt tttgatactc agggtaagcg aatcgtcttc tctggcgata
    15961 cgtcctggtt tcctccgctt gcaacgtttg cccagggggc ggatatcctg gtacatgagg
    16021 cggtacatgt cccttcggta gcaaaactgg ctaatagtat tggcaacgga aaaacgctgg
    16081 ctgaagcgat tgcgtcgcat cacaccacga ttgaagatgt cggtaagatt gctcgcgagg
    16141 cccacgtgaa aaaactggtg ttaagtcatc tggtgcctgc gacggttgcg gatgacgtct
    16201 ggcaacagga agccatgaaa aattacccgg gccctgtcat tgtcggtcat gacaatatga
    16261 cgataagcgt accgtaagca tcagggcagg ggtaaaccaa cgggctgaca tcatgtcagc
    16321 ccgttatgct tttggcgatc agcatgacgc gcagagcttt tgtctaa
//
LOCUS       DAJVBX010000098        16365 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.098, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000098 DAJVBX010000000
VERSION     DAJVBX010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 16365)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16365)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16365
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.098"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            80..814
                     /locus_tag="OPV72_002631"
     CDS             80..814
                     /locus_tag="OPV72_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001520921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HCR9914888.1"
                     /translation="MNSSFRDKDHQIEGHGSPDVYSQIWLLKIRYGLTDRLELSTVGS
                     YINNKRDNLSPEHIEGMSDQSVGVNYALMSQRRGDPFWVTVGGAVLLPTGQDGDNHLP
                     GNSAWGGRVTLTLTKLFTPNIKGDMGFVYQGPFERGNQDVKRGNEFQWNTQVRYMFSD
                     LPLDLGLESAYSNNASGTKKLSNGSVINNHSGTTEWVVGPSFNIAVDSLKLWFGAGAF
                     FPVMQEAKSPTKMEDVRWEFKIGKTW"
     gene            complement(862..2295)
                     /gene="bglA"
                     /locus_tag="OPV72_002632"
     CDS             complement(862..2295)
                     /gene="bglA"
                     /locus_tag="OPV72_002632"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase BglA"
                     /protein_id="HCR9914889.1"
                     /translation="MRKLTLPKDFLWGGAVAAHQVEGGWNKDGKGPSICDVLTSGAHG
                     VPREITQNVVAGKYYPNHEAVDFYGHYKEDIRLFAEMGFKCFRTSIAWTRIFPNGDES
                     QPNEAGLKFYDDMFDELLKYNIEPVITLSHFEMPLHLVQHYGGWTNRKVVDFFVRFAE
                     VVFERYKHKVKYWMTFNEINNQRNWRAPLFGYCCSGVVYTEHENPEETMYQVLHHQFV
                     ASTLAVKAARRINPQMKVGCMLAMVALYPFSCKPEDVMFAQESMRERYVFTDVQLRGY
                     YPSYVLNEWERRGFNIKMEDGDLEVLREGTCDYLGFSYYMTNAVKAEGGSGDAISGFE
                     GSVPNPYVKASDWGWQIDPVGLRYSLCELYERYQKPLFIVENGFGAYDKVEEDGSIND
                     DYRIDYLRAHIEEMKKAVTYDGVDLMGYTPWGCIDCVSFTTGQYSKRYGLIYVNKHDD
                     GTGDMSRSRKKSFNWYKEVIASNGEKL"
     gene            2454..2765
                     /locus_tag="OPV72_002633"
     CDS             2454..2765
                     /locus_tag="OPV72_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HCR9914890.1"
                     /translation="MQPNDITFFQRFQNDILAGRKTITIRDASESHFKAGDALRVGRF
                     EDDGYFCTIEVTGTSTVTLDTLNEKHAQQENMSLDELKRVIAEIYPNQTQFYVIDFKC
                     L"
     gene            2929..3588
                     /locus_tag="OPV72_002634"
     CDS             2929..3588
                     /locus_tag="OPV72_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HCR9914891.1"
                     /translation="MVQKPLMTQGYSLAEEIANSISHGIGLVFGIVGLVLLLVQAVEA
                     NAGMTAIASYSLYGGSMILLFLASTLYHAIPHQRAKIWLKKFDHCAIYLLIAGTYTPF
                     LLVGLDSPLARGLMIVIWSLALFGILFKLTIAHRFKVLSLVTYLAMGWLSLIVVYQLA
                     IKLAIGGVTLLAVGGVVYSLGVIFYVCKRIPYNHAIWHGFVLGGSVCHFLAIYLYVGQ
                     A"
     gene            complement(3704..4684)
                     /gene="ygfZ"
                     /locus_tag="OPV72_002635"
     CDS             complement(3704..4684)
                     /gene="ygfZ"
                     /locus_tag="OPV72_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-modifying protein YgfZ"
                     /protein_id="HCR9914892.1"
                     /translation="MAFISFPPRHPSSSARLPLTLIALDDWALSSITGVDSEKYIQGQ
                     VTADVSQMTEQQHLLAAHCDAKGKMWSTLRLFRERDGFAWIERRSVREAQLTELKKYA
                     VFSKVVIAPDDERVLLGVAGFQARAALANVFSELPNSENQVVRDGASTLLWFEHPAER
                     FLLVTDVATANMLTEKLHGEAELNNSQQWLALDIEAGIPVIDAANSGQFIPQATNLQA
                     LGGISFKKGCYTGQEMVARAKFRGANKRALWLLAGKASRVPEAGEDLELQMGENWRRT
                     GAILAATQLDDGQLLVQAVMNNDLEAESVFRVRDDANTLHIVPLPYSLEE"
     gene            4934..5200
                     /gene="sdhE"
                     /locus_tag="OPV72_002636"
     CDS             4934..5200
                     /gene="sdhE"
                     /locus_tag="OPV72_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD assembly factor SdhE"
                     /protein_id="HCR9914893.1"
                     /translation="MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFV
                     RLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRNRERGPVAI"
     gene            5181..5582
                     /locus_tag="OPV72_002637"
     CDS             5181..5582
                     /locus_tag="OPV72_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YgfX"
                     /protein_id="HCR9914894.1"
                     /translation="MVLWQSDLRVSWRAQWISLLLHGLVAAVILLMPWPLSYTPLWMI
                     LLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQDWTLLRPPWLLKSGMVLRLRAE
                     SGRHQHLWLAADSMEEAEWRELRRILLQQPI"
     gene            complement(5647..6168)
                     /gene="fldB"
                     /locus_tag="OPV72_002638"
     CDS             complement(5647..6168)
                     /gene="fldB"
                     /locus_tag="OPV72_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin FldB"
                     /protein_id="HCR9914895.1"
                     /translation="MNMGLFYGSSTCYTEMAAEKIRDILGPELVTLHNLKDDAPALME
                     QYDVLILGIPTWDFGEIQEDWEAVWEQLDDLNLEGKIVALYGMGDQLGYGEWFLDALG
                     MLHDKLALKGVKFVGYWPTEGYEFTSNKPVIADGQLFVGLALDETNQYDLSDERIQTW
                     CEQILGEMAEHYA"
     gene            6281..7177
                     /gene="xerD"
                     /locus_tag="OPV72_002639"
     CDS             6281..7177
                     /gene="xerD"
                     /locus_tag="OPV72_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HCR9914896.1"
                     /translation="MEQDLARIEQFLDALWLERNLAENTLSAYRRDLSMVVAWLHHRG
                     KTLATAQADDLQTLLAERVEGGYKATSSARLLSAMRRFFQHLYREKYREDDPSAQLAS
                     PKLPQRLPKDLSEAQVERLLQAPLIDQPLELRDKAMLEVLYATGLRVSELVGLTMSDI
                     SLRQGVVRVIGKGNKERLVPLGEEAVYWLETYLEHGRPWLLNGVSIDVLFPSQRAQQM
                     TRQTFWHRIKHYAVLAGIDSEKLSPHVLRHAFATHLLNHGADLRVVQMLLGHSDLSTT
                     QIYTHVATERLRQLHQQHHPRA"
     gene            7201..7914
                     /gene="dsbC"
                     /locus_tag="OPV72_002640"
     CDS             7201..7914
                     /gene="dsbC"
                     /locus_tag="OPV72_002640"
                     /EC_number="5.3.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional protein-disulfide
                     isomerase/oxidoreductase DsbC"
                     /protein_id="HCR9914897.1"
                     /translation="MKKRFMMFTLLAAAFSGVAHADDAAIRQSLAKLGVQSTEIQASP
                     VAGMKTVLTHSGVLYVTDDGKHIIQGPMYDVSGAHPVNVTNKLLMSQLNALEKEMIVY
                     KAPDEKHVITVFTDITCGYCHKLHEEMKDYNALGITVRYLAFPRQGLESQAEQDMKSI
                     WCAKDKNKAFDDAMAGKGVKPASCDVNIADHYALGVQLGVSGTPAIVLSNGYVVPGYQ
                     GPKEMKAFLDEHQKQTSGK"
     gene            7920..9653
                     /gene="recJ"
                     /locus_tag="OPV72_002641"
     CDS             7920..9653
                     /gene="recJ"
                     /locus_tag="OPV72_002641"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HCR9914898.1"
                     /translation="MKQQRQLRRREADETAELPADLPPLLRRLYASRGVRSARELERS
                     VKGMLPWQQLSGIDNAVEILYNAFREGTRIIVVGDFDADGATSTALSVLGMRALGCDN
                     ISYLVPNRFEDGYGLSPEVVDQAKARGAQLIVTVDNGISSHAGVAHAKTLRIPVIVTD
                     HHLPGDTLPDAEAIINPNLRDCEFPSKSLAGVGVAFYLMLALRTFLRDKGWFDERGIA
                     PPNLAELLDLVALGTVADVVPLDANNRILTWQGLSRIRAGKCRPGIKALLEISNRDPQ
                     QLAASDLGFALGPRLNAAGRLDDMSVGVALLLCDNLGEARVLASELDALNQTRKEIEQ
                     GMQAEALILCEKLERSSETLPGGLAMYHPEWHQGVVGILASRIKERFHRPVIAFAPAG
                     DGTLKGSGRSIQGLHMRDALERLDTLYPDLMIKFGGHAMAAGLSLEEHKFEQFQQRFG
                     ELVTEWLDPALLQGEVISDGPLSAAEMSMEVAQLLRDAGPWGQMFPEPLFDGRFRLLQ
                     QRLVGERHLKVMVEPVGGGPLLDGIAFNIDTTCWPDNGVREVELAYKLDINEFRGNRS
                     LQIIIDDIWPL"
     gene            9758..10856
                     /gene="prfB"
                     /locus_tag="OPV72_002642"
     CDS             join(9758..9832,9834..10856)
                     /gene="prfB"
                     /locus_tag="OPV72_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311790.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HCR9914899.1"
                     /translation="MFEINPVNNRIQDLTERTNVLRGYLDYDAKKERLEEVNAELEQP
                     DVWNEPERAQALGKERSSLEAIVDTLDQMTQGLDDVSGLLELAVEADDEETFNEAVAE
                     LNTLEEKLAQLEFRRMFSGEYDSADCYLDIQAGSGGTEAQDWASMLLRMYLRWAEARG
                     FKTEVIEESEGEVAGIKSATIKISGEYAYGWLRTETGVHRLVRKSPFDSGGRRHTSFS
                     SAFVYPEVDDDIDIDINPADLRIDVYRASGAGGQHVNRTESAVRITHIPTGIVTQCQN
                     DRSQHKNKDQAMKQMKAKLYELEMQKKNAEKQAMEDTKSDIGWGSQIRSYVLDDSRIK
                     DLRTGVETRNTQAVLDGSLDQFIEASLKAGL"
     gene            10866..12383
                     /gene="lysS"
                     /locus_tag="OPV72_002643"
     CDS             10866..12383
                     /gene="lysS"
                     /locus_tag="OPV72_002643"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001740376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HCR9914900.1"
                     /translation="MSEQNAQGADEVVDLNNEMKARREKLAALREQGIPFPNDFRRDR
                     TSDQLHAEFDAKEAEELEALNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARD
                     DLPEGVYNEQFKKWDLGDILGAKGKLFKTKTGELSIHCTELRLLTKALRPLPDKFHGL
                     QDQEARYRQRYLDLISNDESRNTFKTRSKILAGIRQFMVARGFMEVETPMMQVIPGGA
                     SARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFT
                     MMELYMAYADYKDLIELTESLFRTLAQDVLGTTQVPYGDEVFDFGKPFEKLTMHEAIK
                     KYRPETDMADLDNFDSAKAIAESIGIHVEKSWGLGRIVTEIFDEVAEAHLIQPTFITE
                     YPAEVSPLARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAQRFLDQVNAKAAG
                     DDEAMFYDEDYVTALEHGLPPTAGLGIGIDRMVMLFTNSHTIRDVILFPAMRPVK"
     gene            complement(12459..13004)
                     /gene="idi"
                     /locus_tag="OPV72_002644"
     CDS             complement(12459..13004)
                     /gene="idi"
                     /locus_tag="OPV72_002644"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HCR9914901.1"
                     /translation="MTEEHVVLLDEQDKPSGTLEKYAAHTLNTPLHLAFSCWLFNEDG
                     QLLVTRRSLSKKAWPGVWTNSVCGHPQQGETTEEAIIRRCRFELGVEITDLTPVYPHF
                     SYRATDPNGIVENEVCPVFAARATSVLQVNSEEVMDYQWSEFKSVWQSLLATPWAFSP
                     WMVMQASDEQARKRLLNYCQR"
     gene            13269..14027
                     /locus_tag="OPV72_002645"
     CDS             13269..14027
                     /locus_tag="OPV72_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HCR9914902.1"
                     /translation="MVLSAGRLNKNSLGIAVLLCTGLLLAGCSSNSGSGTYSGSVYTV
                     KRGDTLYRISRATGTSVKELARLNGISPPYTIEVGQRIKVRGSAKSSSSTRKTSNKTA
                     TKTAAVRPSSSVPKSSWPPVGQRCWVWPANGKVILPYSTAEGGNKGIDIAGARGTPVY
                     AAGAGKVVYVGNQLRGYGNLIMIKHNEDYITAYAHNDTMLVNNGQSVKAGQKIATMGS
                     TDAASVRLHFQIRYRATAIDPLRYLPPQGSKPKC"
     gene            14107..14180
                     /locus_tag="OPV72_002646"
     tRNA            14107..14180
                     /locus_tag="OPV72_002646"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:14139..14141,aa:Gly,seq:ccc)
     gene            14315..15934
                     /locus_tag="OPV72_002647"
     CDS             14315..15934
                     /locus_tag="OPV72_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000935132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCR9914903.1"
                     /translation="MLNSKTYLYQRNGVFYIRLRMKSTDRLTVSHPSHSRYKIASVSL
                     RTKDRRTAMAYSRHIKAALRAIHADRPNASYEEMREHLRDIAEWELSTGRSDLFEPDM
                     RDLYRDQYGEVGENLVHSEPLTIDQHRYINEALNVLKACMKRIEAGDSQPLIDYIDGF
                     DAAAGANDQASATLSVSAPQKTSITEGKHCVTVASLFEQYEQENAQNWKPATLRENKA
                     SHAALIEVFDYLGLNADANVLARADMLRVRDILQQLPKNRKQRFKDVPLVDLLGREDK
                     TDCLDIVTINNKYLIKMAAVFKWAVRNDLIKKNMTEGLELKVPQRKASEARNAFSTEQ
                     VGQLLAAAQVYSQRPSGKPYHYYVTALAAITGARLNEIAQLQVKDVRTTEAGTVYIHI
                     NEDDSSLPGKSIKNAHSDRCVPLVDGAYGFILADFMRLVETRRGADGDDAMVFDGLRL
                     MKNGYGEQVSKWFNRTLLPKVLADRSGLAFHSFRHTVATQLKQHGVELAYAQAIMGHS
                     SGSITYDRYAKEVEVDRLVNVMADVYKEIVG"
BASE COUNT         3994 a         3944 c         4444 g         3983 t
ORIGIN      
        1 cagtaatcta ttaggtgcac cagttaatac cgctatttct ggtggttcag tattgccgga
       61 aggaaagtta ttaaccgccg tgaatagctc atttcgcgat aaagatcatc aaatcgaggg
      121 gcacggaagt ccggatgttt actcccagat atggttattg aagattcgtt acggtttgac
      181 cgacagactg gaattatcaa ctgtgggttc ctatatcaat aacaaacgag acaatctgtc
      241 tcctgagcac atagagggaa tgagcgacca atcggtgggg gtcaattatg ctttaatgag
      301 ccagcgaaga ggtgatccgt tttgggttac ggtaggtggg gcagtattac tacccaccgg
      361 gcaagatgga gataatcatt tgcctgggaa tagcgcctgg ggaggaagag taacactcac
      421 tttaacaaaa ttatttactc ctaacattaa aggggatatg ggttttgtat atcagggacc
      481 atttgagcgc ggtaaccagg acgtgaaacg aggtaacgaa ttccagtgga atacccaggt
      541 gcggtatatg tttagcgatt taccgctgga tcttggtctg gaaagtgcct acagcaataa
      601 tgcctctgga acgaaaaaac tgtctaatgg cagcgtaatt aataaccatt ctggaactac
      661 cgaatgggtt gttggtccgt catttaatat tgccgtcgat tcactgaaat tatggtttgg
      721 tgccggagcc ttcttcccgg taatgcagga agcgaagtcg ccaaccaaaa tggaagatgt
      781 acgctgggaa tttaaaatag gtaagacctg gtaagactcg ttcaaagtgt tacccgccga
      841 ctggcgggta acgtgcagga gttaaagctt ctcgccgttg ctggcaatca cctctttgta
      901 ccagttgaag ctcttcttac gcgaacgcga catatcgccc gtaccgtcat cgtgcttgtt
      961 cacgtagatt aagccgtagc gcttgctgta ctgaccggtg gtgaacgaca cgcagtcgat
     1021 gcagccccac ggcgtgtagc ccatcaggtc gacaccatcg taagtcaccg cttttttcat
     1081 ctcttcaata tgggcgcgca ggtagtcaat gcgatagtcg tcgttgatgc tgccatcttc
     1141 ttctactttg tcgtaagcac caaaaccgtt ttcgacaata aatagcggct tttgatagcg
     1201 ttcgtacagt tcacacaatg aatagcgcag acccaccggg tcaatctgcc agccccagtc
     1261 agatgcttta acataggggt tcggtacgct gccttcaaaa ccggaaatcg catcgccgct
     1321 accgccttcg gctttgaccg cgttggtcat gtaataactg aaaccaagat aatcgcaggt
     1381 gccttcgcgc agcacttcaa gatcgccatc ttccattttg atgttaaatc cgcggcgctc
     1441 ccactcgttc aacacatagg acgggtaata gccgcgcagc tgcacatcgg taaagacgta
     1501 gcgttcacgc atcgattcct gagcaaacat cacatcttct ggtttacagg agaaaggata
     1561 cagcgcgacc atcgccagca tacagccaac tttcatctgt ggattaatac gacgtgccgc
     1621 ttttaccgcc agcgtgctgg cgacaaactg atgatgtaag acctgataca tggtttcttc
     1681 tggattctca tgctcggtat acaccacgcc ggaacagcag tagccaaaca gcggcgcgcg
     1741 ccagtttcgc tggttgttaa tttcgttgaa ggtcatccag tatttgacct tatgtttgta
     1801 gcgttcaaac acgacttcag caaaacggac aaagaaatca accactttac gattggtcca
     1861 gccgccgtag tgctgtacca gatgtaatgg catttcaaag tgagaaaggg tgatgaccgg
     1921 ttcgatgttg tatttgagta actcatcaaa catgtcgtcg tagaatttca gaccggcctc
     1981 gtttggctgg gattcgtcgc cattcgggaa gatacgcgtc caggcaatag aagtacggaa
     2041 gcatttgaac cccatttcgg cgaaaagacg gatgtcttct ttgtaatgtc cgtaaaaatc
     2101 caccgcctcg tggttcggat agtatttgcc agcaacgaca ttctgggtga tttcgcgtgg
     2161 cacgccgtgt gcgccgctgg ttagcacgtc gcagatgctg gggcctttac cgtctttatt
     2221 ccagccgcct tcaacctggt gtgcggcaac cgcgccgccc cataaaaaat cttttggcag
     2281 ggtgagtttt ctcattgttg cataatctca atttatttag tctgttatca ttcattctgc
     2341 accaagtggc atgtaaagcg tacgcaaaat tccaggatgc tcgcgtgtcg gggcaagaac
     2401 acattcagat cgtaacatcc acttcaaggg gccatattca gggggataac cacatgcagc
     2461 caaatgacat tactttcttt caacgtttcc agaatgacat tctggcaggg cgtaaaacca
     2521 tcactattcg tgatgcctcc gagtcccact ttaaagcagg cgatgctcta cgcgtggggc
     2581 ggttcgaaga tgatggctat ttttgcacaa tcgaagtgac aggaacgtca actgtgacgc
     2641 tggatacgtt gaacgaaaaa catgcgcaac aggaaaatat gtcgcttgat gagctgaaac
     2701 gggtcattgc tgaaatctat cccaaccaga cgcaatttta tgtgattgat tttaaatgcc
     2761 tttgataaat atgaacgcgt gttagttgag tttttgtagt taatttgttg aataataaac
     2821 aaaatttaat tttgcgaatt tattttagct aacatgtgtt cactggaacc attctcagtt
     2881 acgctagagg tgcagttcat cgttatgaac gtttctccgg agtaagttat ggtgcaaaaa
     2941 ccattaatga cgcagggata ttcgctggct gaggaaatcg ccaacagtat tagccacggc
     3001 attggattgg tatttggtat tgtcggcctg gtgctgttgt tggttcaggc ggtagaggcg
     3061 aatgcgggta tgacggctat cgccagctac agtttatatg gcgggagcat gatcctgctt
     3121 tttcttgcct caacgcttta tcatgccatt cctcatcagc gggcaaaaat ctggttaaag
     3181 aaatttgatc actgcgctat ctatctgctc attgccggaa cctatacgcc atttctgctg
     3241 gtaggtctgg attcgccgct ggcgcgcgga ctaatgattg tgatctggag cctggcgcta
     3301 ttcggtatcc tcttcaagtt gacgattgcg caccgattta aagtgctttc actggttacg
     3361 tatctggcaa tgggctggct gtcgctgata gtggtttatc agttggcgat taagctggcg
     3421 ataggcggcg tgacgctgct ggcggtaggt ggcgtcgttt actcgctggg cgtaattttc
     3481 tatgtttgca aacgcatacc ttataaccac gccatctggc atggctttgt gctgggcggc
     3541 agcgtgtgcc acttcctggc catctatttg tatgtgggac aggcgtaatt cccggatgcc
     3601 cgtgccggat ggcggcgctg tcgtacctta tccggcctac gagagcagca cgtgcgagcc
     3661 tgatggcgtt gcgctatcag gctatccgac ttttaacgtg atatcactct tccaacgagt
     3721 aaggcagcgg gacgatatgc agggtgttgg catcgtcgcg aacgcggaag acgctttcgg
     3781 cttctaaatc gttattcatg acggcctgaa ccagtaactg accatcgtcc aactgtgtcg
     3841 ccgccagaat agcgccggta cgacgccagt tctcgcccat ctgtagctcc agatcttctc
     3901 ctgcttccgg tacccggctg gctttgcccg ccagcaacca aagcgcgcgt ttattggcgc
     3961 cgcggaattt tgcccgtgcg accatctcct gtccggtgta gcagcctttc ttgaagctga
     4021 tgccgcccag cgcctgtagg ttagtcgcct gggggataaa ctgaccgctg ttcgccgcgt
     4081 caatcaccgg aatgcctgct tcaatatcca acgccagcca ctgttgactg ttattcagtt
     4141 cggcttcgcc atgcaacttc tccgttaaca tgttggccgt cgcgacatcg gtgacaagca
     4201 ggaatcgttc cgcaggatgt tcaaaccata gcagcgtgga ggcgccgtct ctgaccacct
     4261 gattttcact attgggcagt tcgctaaaga cattagccag cgccgcgcgg gcctgaaaac
     4321 cggccacgcc aagcaatacg cgttcgtcat ccggcgcgat gactactttg gaaaatacgg
     4381 cgtacttttt cagctccgtt aattgcgctt cacgcacgct acggcgttca atccaggcga
     4441 aaccgtcgcg ctcacggaac agtcgcagag tgctccacat cttaccttta gcatcgcagt
     4501 gggcggcgag aaggtgttgc tgttcagtca tctggcttac gtcagcggtg acctggccct
     4561 gaatatactt ttcactgtct acgccggtaa tggacgacag cgcccagtcg tcaagcgcga
     4621 tcagcgtcag cggcaggcgg gctgacgatg agggatgacg tggtggaaag gagataaaag
     4681 ccataaataa tgtcctggtt agctgcaaca ataatggtta atggtaaaag agccatcggt
     4741 cattgcaagt gctttaaata gcccattgaa agcggattga tcgttttgcg aggtggtatc
     4801 caaaacggat gaacatattg attcccagcc ttctatttcg cgatcgcgtt ccagattact
     4861 gagattcccg taaaacaacg ccaaaaacac gttacaatag cccggtactt cattttcgcg
     4921 aggcaggaag aacatggata ttcacaataa agcacgtatt cactgggcat gtcgtcgcgg
     4981 tatgcgcgaa cttgatattt ccatcatgcc gttttttgaa catgagtacg atagtttaag
     5041 tgatgaagaa aagcgtattt ttgtccgttt gttgcagagt gatgacccgg atttatttaa
     5101 ctggttaatg aatcacggta aaccggctga cgctgaactg gaacagatgg tccgactcat
     5161 tcagacacgg aatcgggaac gtggtcctgt ggcaatctga tttacgcgtc tcatggcgcg
     5221 ctcagtggat ctcattgctc cttcatgggc tggttgccgc ggtgatttta ttgatgccct
     5281 ggccgctgag ttataccccg ttatggatga tactactgtc gctggtcgtg tttgactgtg
     5341 tacgtagcca gcgcaggatt aatacctgcc agggagagat caagctactc atggacgggc
     5401 gcttacgctg gcagggacag gactggacgc tcttgcgtcc tccctggtta ctgaagagcg
     5461 ggatggtgtt gcgtttacgc gcagagtctg gacgtcatca gcatttatgg ctggcggcgg
     5521 atagcatgga agaagcggaa tggcgtgagt tgcgtcggat actgttacag cagccgatat
     5581 agcgccaaca ctgacggaac gacgcaaacg cggttccgtc gagagggaaa tacagcgagt
     5641 aaggcttcag gcgtagtgtt cggccatttc gccgagaatt tgttcacacc aggtctgtat
     5701 acgctcatcg ctgagatcgt actggttcgt ttcatccagc gccaggccga caaacagttg
     5761 cccatccgca atgaccggtt tattgctggt aaattcgtag ccttctgtgg gccagtagcc
     5821 gacaaattta acgcctttga gggcaagttt gtcatgcaac atacccagcg catccaggaa
     5881 ccactcgccg tagccgagtt ggtcgcccat accgtaaagc gcaacgattt tgccttccag
     5941 attgagatcg tccagttgct cccagacggc ttcccagtcc tcctgaattt cgccaaaatc
     6001 ccaggtgggg atgcctaaaa tgagcacgtc gtactgctcc attaaggcgg gggcgtcatc
     6061 cttgaggtta tgtaatgtca ccagctccgg gccgaggata tcgcgaattt tctctgcggc
     6121 catctcggtg tagcacgtgc tggaaccgta aaaaagaccc atgttcatta cgttacatct
     6181 cgattctgct atagcgttgc gggtagtgta acagaatcgc tgcattcacg gcacaatgag
     6241 gcataatgca ccaaaagtaa gcgtgaagta gggagcgcga atggaacagg atttagcgcg
     6301 tattgagcag tttctggatg ccctgtggct ggaacgaaat ctggcggaaa atacattaag
     6361 cgcgtatcgt cgcgatttat cgatggtcgt tgcgtggttg catcatcgcg gaaaaacgct
     6421 tgcgacggcg caggctgatg atttacaaac gctattggct gaacgggtgg agggcggata
     6481 caaagcgacc agctccgcac gcctgttaag cgctatgcgg cgctttttcc agcatctgta
     6541 ccgtgaaaag tatcgtgagg atgatccgag cgcacagttg gcctcgccta agcttccgca
     6601 gcgtttaccg aaagacctta gcgaggcgca ggttgaacgg ctcttgcagg cgccgcttat
     6661 tgatcaacct ttggagttgc gcgataaagc tatgttggaa gtgctgtatg ccaccggttt
     6721 gcgcgtgtcg gaactggtgg ggctgacaat gagcgatatc agtctgcggc agggcgtggt
     6781 gcgggttatc ggtaaaggca ataaagagcg gttggtgccg ttaggcgaag aggcggtata
     6841 ttggctggaa acgtatctgg agcatgggcg tccctggtta ctcaatggcg tatcgattga
     6901 cgtattattc cccagtcagc gtgcgcagca gatgacgcga cagaccttct ggcaccgtat
     6961 taaacattat gcggtactgg ctggaattga tagcgaaaaa ctatcgccgc atgttttacg
     7021 tcacgctttc gccacgcatt tgctgaatca cggcgccgac ttgcgcgttg tacaaatgct
     7081 acttgggcat agcgatcttt cgacgacaca aatttatacg catgtcgcaa cggagcgttt
     7141 gcgtcaactt catcaacagc accatccgcg ggcatgagtg ctgacaggaa aggatagttt
     7201 atgaaaaagc gttttatgat gttcacttta ctggcggcgg cgttttcagg cgtggcccat
     7261 gcggatgatg cggctatccg tcagtcgctg gctaagctgg gcgttcagag tacggaaatt
     7321 caggcctcgc cagtggcagg gatgaaaacc gtcctcactc acagcggcgt actgtacgtc
     7381 actgacgacg gcaaacatat tattcaaggg ccgatgtatg acgtgagcgg cgcgcatccg
     7441 gtaaatgtga cgaacaaact gctgatgagc cagctaaatg cgctggaaaa agagatgatc
     7501 gtctataaag cgccggatga gaaacatgtc attactgttt ttaccgatat cacctgcggc
     7561 tattgtcata agctacatga agagatgaaa gattataacg cgctggggat cacggtacgt
     7621 tatctggctt ttccgcgcca ggggctggaa agccaggcgg agcaggatat gaaatctatc
     7681 tggtgcgcca aagacaaaaa caaagcgttt gatgacgcca tggcaggtaa gggcgtgaaa
     7741 ccggcaagct gtgacgtgaa cattgctgat cattatgcgt tgggcgtgca gttgggcgtt
     7801 agcggtacgc cagccattgt attgagtaac ggctatgtgg tgcctggcta tcagggaccg
     7861 aaagagatga aagcgtttct tgatgagcat caaaaacaga ccagtggtaa ataatacgcg
     7921 tgaaacaaca gagacaactt cgtcggcgcg aggctgatga gacggcggaa ctccccgccg
     7981 atcttcctcc attactacga cgtctatatg ccagccgggg cgttcgtagc gcccgcgaac
     8041 tggagcgcag cgtgaaagga atgctgccct ggcaacagct tagcggcata gataacgcgg
     8101 tggagatcct ctacaacgcc tttcgcgaag gtacccgcat tattgttgtt ggcgattttg
     8161 acgccgacgg cgcgaccagt actgcgctaa gcgtattggg aatgcgtgcg ttgggatgtg
     8221 acaacatcag ttatctggtg cctaatcgct ttgaggacgg ctacggttta agcccggaag
     8281 tggtcgatca ggcgaaggcg cgcggcgcac agcttatcgt caccgtagac aacggcattt
     8341 catcccacgc tggcgtagcg catgcaaaga cgttgaggat tccggtgatc gtgaccgatc
     8401 accacctgcc tggcgacacg ttgccggatg ccgaagcgat tattaatccc aatctgcgcg
     8461 actgcgaatt cccgtctaag tcgctggcgg gcgtcggcgt ggcgttttac ctgatgctgg
     8521 cgttgcgaac atttttgcgc gacaaaggat ggttcgacga gcgcggcatc gcgccgccga
     8581 atctggcgga gctgctggat ttagtggcgt tgggaacggt agcagacgtt gtgccgctgg
     8641 acgccaacaa ccgtattctg acctggcaag ggctaagtcg tattcgtgcc gggaaatgcc
     8701 gtccgggaat taaagcgttg ctggagatat cgaatcgcga tccgcagcag cttgccgcca
     8761 gtgatttagg cttcgcgttg gggcctcgtc tgaatgccgc cggcaggctg gatgatatgt
     8821 ccgttggcgt ggcgttactg ttgtgcgaca acctcggcga agcgcgtgtt ctggccagcg
     8881 agctggatgc gcttaaccag acgcgcaaag aaatagagca ggggatgcag gcggaagcgc
     8941 ttatcctgtg cgaaaagctt gagcgcagta gtgaaacgct tccgggcggt ctggcgatgt
     9001 atcatcctga atggcatcag ggcgtggtcg gaattctggc gtcgcgcatt aaagagcgtt
     9061 ttcaccgccc ggtgatcgcc tttgcacctg cgggcgacgg cacgctaaaa ggctcaggcc
     9121 gttcgattca ggggttgcat atgcgcgatg cgctggaaag gctggatacg ctttaccctg
     9181 atctgatgat caagttcggc ggtcatgcga tggcggcggg attgtcgctg gaagagcata
     9241 aattcgagca gtttcagcaa cgttttggcg agctggtgac ggaatggctc gatcctgccc
     9301 tgttgcaagg cgaggtgatc tccgatggtc cattaagcgc ggcggagatg tctatggaag
     9361 tggcgcaact gttgcgggat gccggaccgt gggggcaaat gttcccggaa ccgttattcg
     9421 atggtcgttt ccgtctgcta caacagcgtc tggtgggcga gcgccacctc aaggtgatgg
     9481 tggagcctgt cggcggcggc ccgctgttgg atggcatcgc atttaatatt gatacgacct
     9541 gttggccgga taacggcgtg cgggaggtag aactggctta taaactggac attaacgagt
     9601 ttcgcggcaa ccgtagttta cagattatta tcgatgatat ttggccgcta tgatcggggc
     9661 gatttaacaa cactttcgct gtaattaagg ggcgaaatcc gctaatattt cacccttata
     9721 accgcatttt gacaagtcaa ataaaagaaa tcagaccatg tttgaaatta acccggtgaa
     9781 taaccgcatt caggacctca cggaacgcac caacgttctt agggggtatc tttgactacg
     9841 atgctaagaa agagcgtctg gaagaagtaa acgccgagct ggaacagccg gatgtctgga
     9901 acgaacctga gcgcgcgcag gcgctgggaa aagaacgttc atcgctcgaa gcgattgtcg
     9961 atacgcttga tcaaatgact caggggctgg acgacgtttc cgggctgctg gaactagcgg
    10021 tagaagctga cgacgaagag acgtttaacg aagccgtcgc ggaactgaat acgctggaag
    10081 agaagctggc gcagttggaa ttccgccgga tgttctccgg cgagtacgat agcgccgatt
    10141 gctatctcga tattcaggcc ggttccggtg gtactgaagc acaggactgg gccagcatgt
    10201 tgctgcgtat gtatctgcgt tgggcggaag cgcgcggctt caagacggaa gtcattgaag
    10261 agtcggaagg ggaagtcgcc ggcattaagt ccgcgactat caaaatctcc ggcgaatatg
    10321 cctatggctg gctgcgcact gaaaccggcg tacatcgtct ggtgcgtaaa agcccgttcg
    10381 actccggcgg tcgccgtcat acctcgttta gctccgcgtt tgtgtatccg gaagtggacg
    10441 acgatatcga tatcgacatt aacccggcgg atctgcgtat cgacgtctat cgcgcgtctg
    10501 gcgcaggcgg tcagcacgtt aaccgtacgg aatccgcagt gcgtatcacc catattccca
    10561 ccgggatcgt gacgcagtgc cagaacgacc gttcgcagca caaaaacaaa gaccaggcca
    10621 tgaagcagat gaaagcgaag ctttatgaac tggagatgca gaaaaagaac gctgaaaaac
    10681 aggcgatgga agacactaag tctgatatcg gctggggaag ccagattcgt tcctatgtcc
    10741 tggacgattc ccgcattaaa gacctgcgta ctggggtgga aacccgcaat acacaggcgg
    10801 tactggacgg tagtctggat caatttatcg aagcaagttt gaaagcaggg ctatgaggaa
    10861 tcaacatgtc tgaacaaaac gcacagggcg ctgacgaggt agtcgatctt aacaatgaaa
    10921 tgaaggcacg tcgcgagaag ctggctgcac tgcgtgagca gggtatcccg ttcccgaacg
    10981 atttccgtcg tgaccgtacc tcagaccaac tgcacgcaga gtttgacgcg aaagaagctg
    11041 aagaactgga agcgctgaat attgaagtgt ccgtcgcggg ccgtatgatg actcgccgta
    11101 ttatgggtaa agcctctttt gttaccctgc aagacgtagg cggccgcatt cagctgtatg
    11161 tggcgcgcga tgatctgccg gaaggcgttt acaacgagca gttcaagaag tgggatcttg
    11221 gcgatatcct cggcgcgaaa ggtaagctgt tcaaaaccaa aaccggcgag ctgtctatcc
    11281 actgcaccga actgcgcctg ctgacgaaag cgctgcgtcc gttgccggat aaattccacg
    11341 gcctgcagga ccaggaagcg cgctatcgcc agcgttatct ggatctcatc tctaacgatg
    11401 aatcccgtaa taccttcaaa acccgttcga agatcctggc cggtattcgc cagtttatgg
    11461 ttgctcgcgg ctttatggaa gtcgaaacgc cgatgatgca ggtgatccca ggcggcgcgt
    11521 ctgcccgtcc gtttatcacc catcacaacg cgctggatct ggacatgtac ctgcgtatcg
    11581 cgccagaact gtacctgaag cgtctggtgg ttggcggctt cgaacgcgta ttcgaaatta
    11641 accgtaactt ccgtaacgaa ggcatctccg tgcgccataa tcctgagttc accatgatgg
    11701 aactctatat ggcgtatgcg gactacaaag acctgatcga gctgactgag tctctgttcc
    11761 gtacgctggc gcaggatgtt ctgggcacca cccaggttcc atacggtgat gaagtgtttg
    11821 acttcggtaa gccgttcgaa aaactgacca tgcatgaagc gatcaagaaa tatcgtccgg
    11881 aaacggatat ggctgatctg gacaacttcg actccgcgaa ggcgattgct gaaagcatcg
    11941 gcattcacgt cgagaagagc tggggtctgg gccgtatcgt caccgagatc tttgacgaag
    12001 tcgctgaagc gcatctgatt cagccgacct tcatcaccga atatccggct gaagtgtctc
    12061 cgctggcgcg tcgtaatgat gtgaacccgg aaatcactga ccgcttcgag ttctttatcg
    12121 gcggtcgtga aatcggcaat ggctttagcg agttgaacga tgcggaagac caggcgcagc
    12181 gtttcctgga tcaggttaat gcaaaagcgg cgggcgacga cgaagccatg ttctacgacg
    12241 aagactacgt gacggcgctg gaacacggtt taccgccgac agcgggtctg ggaattggta
    12301 tcgaccgtat ggtgatgctg tttactaaca gccacacgat tcgcgacgtt attctgttcc
    12361 cggcgatgcg tccggtgaaa taagatgtaa attgccggat ggggcattag ccgccatccg
    12421 gcatctcttc gttcagacgt agcgccatca ggcaatcttt aacgctggca gtaattgagc
    12481 agtcgtttac gcgcttgttc gtctgacgct tgcatgacca tccacgggct aaatgcccac
    12541 ggcgtagcga gaaggctttg ccatacgctt ttaaattcgc tccactgata gtccatcacc
    12601 tcttcgctgt taacctgtaa cacactggtt gcccgcgcgg caaataccgg acagacttca
    12661 ttttccacaa taccgtttgg atctgtcgcc cgatagctga agtgcggata gacgggggtg
    12721 agatcggtaa tttccacgcc gagttcgaac cgacaacggc ggatgatcgc ctcttcggtg
    12781 gtttcgcctt gttgcggatg accgcaaacc gaattcgtcc acacgcctgg ccaggctttc
    12841 ttgctcagcg accgtcgtgt taccagcaat tggccatctt cgttaaatag ccagcaggag
    12901 aaagccagat gcaaaggcgt attaagcgta tgagccgcat acttttccag tgtgccggaa
    12961 ggcttatcct gctcatccaa taaaacgaca tgttcctcag tcatgaaagc tcctgaaaat
    13021 taaaatgacc cggcagcatg gccaggccat atactcagac gatcagcgta gcgcataaca
    13081 gaaagaaagg cattaccaaa acaggccctg acagaacgca gacgagcgct attgtgccgt
    13141 gattcgatat tatgctggca tatcggatat tcgcggcatc atcatccaca cggacccttt
    13201 ccggcgtcaa tggattgggc atacggcatt tggctgctat cataaggcgt ctgtcaatag
    13261 agtgaggaat ggttttgagc gcaggacgcc tgaacaaaaa tagcctgggt attgcggtgc
    13321 tgttatgcac agggctgctg ctggcggggt gttccagtaa ttccggctca ggaacgtatt
    13381 ccggctccgt ctataccgtt aagcgcggcg atacgttgta tcgtatatcg cgcgctacgg
    13441 gaaccagcgt gaaagaactg gcccgactga atggcatttc tccgccttat actattgagg
    13501 tggggcagcg aattaaagtg cgcggcagcg caaagagtag cagttcaaca cgcaaaacca
    13561 gcaataaaac agcaacaaaa actgctgcgg tcagaccgtc atcttcggtg ccaaaatcct
    13621 cctggccgcc ggtggggcag cgttgttggg tatggcctgc taacggtaaa gtgattttac
    13681 cttattccac cgcggagggc ggaaataagg ggatcgatat tgcgggcgcg cgcggaacgc
    13741 ctgtttatgc ggcgggagcg ggtaaagttg tctatgtcgg gaaccagctg cgcggttacg
    13801 gcaatctcat catgattaag cacaatgaag attacattac ggcttacgct cataatgaca
    13861 ccatgctggt taataatgga caaagcgtta aagcggggca aaaaatcgct acgatgggca
    13921 gcacggatgc cgcatccgta agactacact tccagattcg ctaccgggcg acggccatcg
    13981 atccgctgcg ttatctgccg ccgcagggga gtaaaccgaa gtgctgacgg cgaattaatc
    14041 gccagtcagc cagtaagtct cttgccaacc agagcgtaag gtttataatg ccttacgcat
    14101 ctcaaagcgg gcgtagttca atggtagaac gagagcttcc caagctctat acgagggttc
    14161 gattcccttc gcccgctcca tgacctttct taaagtactc caacctactg aatcctaagg
    14221 gatacggctt taagccttcc gctagtttta ctcactgtaa ccaacactgt aactaaattt
    14281 gttgaaatag tgagcagact taagatctca gtacatgctc aactcaaaaa cctatcttta
    14341 tcagcgcaat ggcgtctttt atatccgcct caggatgaag tccacagatc gcctgaccgt
    14401 ttcacatcct tcccatagcc gttataaaat agcgtcagta tcactacgga ctaaggatag
    14461 acgtacagct atggcttact cacggcatat caaggcagca cttagggcaa tccatgcaga
    14521 cagacccaac gcctcctatg aggaaatgag ggaacacctg agggacatcg cagagtggga
    14581 gttgtctaca ggtcgttcag acctcttcga gccagatatg agagatctat accgtgacca
    14641 gtatggggaa gtgggagaga atcttgtcca tagcgagcca ctgactattg accagcatcg
    14701 ctatattaat gaggctctta atgtactcaa ggcctgcatg aagcgcattg aagcgggaga
    14761 tagccagcca cttatagatt atatagatgg atttgatgct gctgctggtg ctaatgacca
    14821 agcctctgca actctatctg ttagtgctcc ccaaaaaaca agcattactg aaggcaaaca
    14881 ctgcgtaacc gttgcttctc tctttgagca gtacgagcag gaaaacgccc agaactggaa
    14941 gccagcaaca ttacgagaaa acaaagcttc tcatgctgcg ttaatcgagg tttttgatta
    15001 tctgggcctc aatgctgacg ccaatgtgtt agctcgtgcg gatatgctta gggttcggga
    15061 tatcctccag caattgccga agaatcgtaa gcagcgtttc aaagatgttc cgttggttga
    15121 cctgctaggt cgtgaggata aaaccgattg tctggatatt gttaccatca ataataaata
    15181 tctcattaag atggcggctg ttttcaagtg ggccgtgcgt aatgacctga ttaaaaagaa
    15241 tatgacagaa gggctagagc ttaaggttcc ccagcgtaaa gcctctgagg cgcgtaatgc
    15301 tttctctacg gagcaggtag gacaactact ggctgccgcc caagtttact cacagagacc
    15361 ttctggtaag ccgtatcatt attatgttac cgccttggct gctatcactg gggcgagact
    15421 caatgaaata gcccaactac aggtcaaaga cgtcaggacc actgaggcgg gaaccgttta
    15481 tattcatatc aatgaagacg atagtagtct acccggtaag agcatcaaga acgctcatag
    15541 tgaccgctgt gtgcctctgg tcgatggggc ctatggtttt atattggctg actttatgag
    15601 gttggttgag acccgtagag gcgctgatgg tgatgacgct atggtgttcg atggtcttcg
    15661 cctcatgaag aacggttacg gtgagcaggt gagtaaatgg tttaatcgga cgttgttgcc
    15721 taaagtcctc gcagatcgta gcggcttagc gtttcactcg tttagacata cagttgcgac
    15781 ccagttaaaa caacatgggg tcgagttggc gtatgcacag gcgatcatgg ggcatagttc
    15841 agggtctatt acttacgacc gttatgctaa agaggttgag gttgataggc tggtcaatgt
    15901 gatggctgat gtttataagg agattgtggg gtaaccaagc tgtccccccc cggggagatt
    15961 tgccttgagg ctgaccatag tcgatgacca tattgctaca ggcctgtgtg gtcatgtttt
    16021 tgactcacag ttttcactac ttgtcaagga tttctaatac gactcactat agggagaagg
    16081 gacacaaaaa gttttctctc tttctctctc ttctgggaca cttgctacta ctactacagg
    16141 tagctctaac tctaactcta accgtaactt atcgcatcct ttcaggggcg ggatgaccaa
    16201 ttacagacac caagcgttct acttaaagtg aatgcttcct gtgtgctctg ggtcagtcga
    16261 taagtgaata gcaatagaca tcatattaaa tatggtctct accctacagg ggcttaactt
    16321 aaagttaact taaagacaca attaaagatt aacttatagt attaa
//
LOCUS       DAJVBX010000099        16188 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.099, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000099 DAJVBX010000000
VERSION     DAJVBX010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 16188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16188
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.099"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            121..1518
                     /locus_tag="OPV72_002648"
     CDS             121..1518
                     /locus_tag="OPV72_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HCR9914904.1"
                     /translation="MTDSIMQNYNQLREQVINGDRRFQHKDGHLCFEGVDLDALARQY
                     PTPFYVFSEPEIIRNIHEIQQAFAAHKNTKTFFASKTCSVMGVLKAIRDAGICAEANS
                     QYEVRKCLEIGFRGDQIVFNGVVKKPADLEYAIANDLYLINVDSLYELEHIDAISRKL
                     KKVANVCVRVEPNVPSATHAELVTAFHAKSGLDLEQAEETCRRILAMPYVHLRGLHMH
                     VGDQVPESEPFAKATKVLVDESRRLEEVLGIKFDLINVGGGIPVPYKYDDENGDPLKD
                     NMYAGITAQDFADAVIREVHKWRTDVEICIEPGRKVTGSAAVLLTEVSCEKRKTNYDL
                     NGNVECHVEWKFVDAGYSVLSDSQHFDWFFYVYNASRMTAAHDAWIKLAGPLCDGGDY
                     FHMGVKGEEFLLPKETHVGDIVAFLDAGAYTIESQTVYNNRPRTGVVMIDKNGETRLI
                     RREDSYEDMVKYDIY"
     gene            1609..3030
                     /locus_tag="OPV72_002649"
     CDS             1609..3030
                     /locus_tag="OPV72_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCR9914905.1"
                     /translation="MSNTNSGLLGIKDIVFMNVIAILSLRQIPNVAPYGASAMLLWVI
                     AAFCLFFPLAMVCGELSTGWPKDGGIFVWIKEAFGKRIAWIVVVCFLFSCVLFFPLML
                     QFGFTALGYMIGGGLAENKAFIGIGSAVIFWLLTLMNIRGMEWTKIINSISAWCGVFI
                     PSAILILLAVVWLCTGHQMQTDYTTAKNWIPDLGHWDTIVFLSSMMFAFAGLEVAPMI
                     AGRTRNPQRDFPRAMAVSAAVIVGIYMVGTWALNTLLPAGKTDIVAGVMQAMHAAADT
                     LHMPWLIPVMAICMFFGALGQINSWLVGPIYMLQEASREDNLLGDRIGKLHPVWKTPA
                     FALTIQAIIVTVLCFSTFISPSVAAAYWMLTALTTITYFIPYLVMFPAFWRLRKTQPD
                     TPRSFKIPGKVLPAILPALGFLSIAFAVALLFIPPSQIDMGGYFQYAGKIIGGAVLAV
                     VVAEYIYHRAQKRNARLSMAGGK"
     gene            3032..4135
                     /locus_tag="OPV72_002650"
     CDS             3032..4135
                     /locus_tag="OPV72_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/ornithine racemase family PLP-dependent
                     enzyme"
                     /protein_id="HCR9914906.1"
                     /translation="MYMPVLEINLRKLEENARTEKALLASSGIDVMAVNKVFDGCVET
                     AQAVLNGGITVIAESRTYNLKKIRETGCTTCLLRSPCLSEIEDVVRYADISLNSEPVV
                     LRALSQEAQRQGKTHQVLLMVDMGDLREGIWFGEYQRILETVTLITGLPGLELYGLGT
                     NFNCYGTVLPTVKNGEDFLALAARLEADSGIPVRRLSAGNCTSYHLLDKGIWPQGLNH
                     LRIGGLHEFGIEYVDMKYLNEFHHSAKPVDKACSDMYILEAEIIELNSKPTVPVGELG
                     VDAFLQSKTFVDRGIRRRALLAFGRQDVPSDNCVPCDDAITILGQTSDHTLVDIEDCR
                     QSLKVGDVVRFELDYTGLLMACQTKGVAWRFTR"
     gene            4199..5605
                     /locus_tag="OPV72_002651"
                     /pseudo
     CDS             4199..5605
                     /locus_tag="OPV72_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461299.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
     gene            5632..6201
                     /locus_tag="OPV72_002652"
     CDS             5632..6201
                     /locus_tag="OPV72_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HCR9914907.1"
                     /translation="MKRLIVGISGASGAIYGVRLLQILRDVDSVETHLVMSQAARQTL
                     ALETHFSLREVQALADVTHDARDIAASISSGSYPTAGMVILPCSIKTLSGIVHSYTDG
                     LLTRAADVILKERRPLVLCVRETPLHIGHLRLMTQAAEIGAVIMPPVPAFYHLPQTLD
                     DVINQTVNRVLDQFDIPLPHDLFVRWQGA"
     gene            6490..7272
                     /gene="argT"
                     /locus_tag="OPV72_002653"
     CDS             6490..7272
                     /gene="argT"
                     /locus_tag="OPV72_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine/arginine/ornithine ABC transporter
                     substrate-binding protein ArgT"
                     /protein_id="HCR9914908.1"
                     /translation="MKKTVLALSLLIGLGATAASYAALPQTVRIGTDTTYAPFSSKDA
                     KGDFIGFDIDLGNEMCKRMQVKCTWVASDFDALIPSLKAKKIDAIISSLSITDKRQQE
                     IAFSDKLYAADSRLIAAKGSPIQPTLESLKGKHVGVLQGSTQEAYANDNWRTKGVDVV
                     AYANQDLIYSDLTAGRLDAALQDEVAASEGFLKQPAGKEYAFAGPSVKDKKYFGDGTG
                     VGLRKDDTELKAAFDKALTELRQDGTYDKMAKKYFDFNVYGD"
     gene            7510..8292
                     /gene="hisJ"
                     /locus_tag="OPV72_002654"
     CDS             7510..8292
                     /gene="hisJ"
                     /locus_tag="OPV72_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ABC transporter substrate-binding
                     protein HisJ"
                     /protein_id="HCR9914909.1"
                     /translation="MKKLALSLSLVLAFSSATAAFAAIPQKIRIGTDPTYAPFESKNA
                     QGELVGFDIDLAKELCNRINTQCTFVENPLDALIPSLKAKKIDAIMSSLSITEKRQQE
                     IAFTDKLYAADSRLVVAKNSDIQPTVASLKGKRVGVLQGTTQETFGNEHWAPKGIEIV
                     SYQGQDNIYSDLTAGRIDAAFQDEVAASEGFLKQPIGKDYKFGGPAVKDEKLFGVGTG
                     MGLRKEDNELREALNKAFAEMRADGTYEKLAKKYFDFDVYGG"
     gene            8475..9161
                     /locus_tag="OPV72_002655"
     CDS             8475..9161
                     /locus_tag="OPV72_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012124147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ABC transporter permease HisQ"
                     /protein_id="HCR9914910.1"
                     /translation="MLYGFSGVILQGAIVTLELALSSVVLAVLIGLVGAGAKLSQNRV
                     TGLIFEGYTTLIRGVPDLVLMLLIFYGLQIALNVVTDSLGIDQIDIDPMVAGIITLGF
                     IYGAYFTETFRGAFMAVPKGHIEAATAFGFTHGQTFRRIMFPAMMRYALPGIGNNWQV
                     ILKATALVSLLGLEDVVKATQLAGKSTWEPFYFAVVCGLIYLVFTTVSNGVLLLLERR
                     YSVGVKRADL"
     gene            9158..9865
                     /gene="hisM"
                     /locus_tag="OPV72_002656"
     CDS             9158..9865
                     /gene="hisM"
                     /locus_tag="OPV72_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ABC transporter permease HisM"
                     /protein_id="HCR9914911.1"
                     /translation="MIEIIQEYWKSLLWTDGYRFTGVAITLWLLISSVVMGGLLAVIL
                     AVGRVSSNKFIRFPIWLFTYIFRGTPLYVQLLVFYSGMYTLEIVKGTDLLNAFFRSGL
                     NCTVLALTLNTCAYTTEIFAGAIRSVPHGEIEAARAYGFSSFKMYRCIILPSALRIAL
                     PAYSNEVILMLHSTALAFTATVPDLLKIARDINSATYQPFTAFGIAAVLYLLISYVLI
                     SLFRRAERRWLQHVSSK"
     gene            9879..10652
                     /gene="hisP"
                     /locus_tag="OPV72_002657"
     CDS             9879..10652
                     /gene="hisP"
                     /locus_tag="OPV72_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ABC transporter ATP-binding protein
                     HisP"
                     /protein_id="HCR9914912.1"
                     /translation="MSENKLHVIDLHKRYGGHEVLKGVSLQARAGDVISIIGSSGSGK
                     STFLRCINFLEKSSEGAIIVNGQNINLVRDKDGQLKVADKNQLRLLRTRLTMVFQHFN
                     LWNHMTVLENVMEAPIQVLGLSKHDARERALKYLAKVGIDERAQGKYPVHLSGGQQQR
                     VSIARALAMEPDVLLFDEPTSALDPELVGEVLRIMQQLAEEGKTMVVVTHEMGFARHV
                     SSHVIFLHQGKIEEEGNPEQVFGNPQSPRLQQFLKGSLK"
     gene            complement(10704..11597)
                     /locus_tag="OPV72_002658"
     CDS             complement(10704..11597)
                     /locus_tag="OPV72_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01777 family oxidoreductase"
                     /protein_id="HCR9914913.1"
                     /translation="MQILITGGTGLIGRHLIPRLLILGHQVTVVTRNPDNARQILDSR
                     VTLWKGLAEREHLNEIDAIINLAGEPIADKRWTSQQKERLCQSRWAITQKLVDLIHAS
                     ATPPSVLISGSATGYYGDLGDVVVTEDEPPHNEFTHKLCARWEQIACRAQSDQTRVCL
                     LRTGVVLAPQGGILGKMVPPFRLGLGGPVGNGRQYLAWIHIDDMVNGILWLLDNDLRG
                     PFNMVSPYPVHNEQFAHALGRALRRPAIIRIPATAIRLLMGESSVLVLGGQRALPKRL
                     EAAGFAFRWYDLEEALADVIR"
     gene            complement(11721..12368)
                     /gene="yfcG"
                     /locus_tag="OPV72_002659"
     CDS             complement(11721..12368)
                     /gene="yfcG"
                     /locus_tag="OPV72_002659"
                     /EC_number="1.8.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GSH-dependent disulfide bond oxidoreductase"
                     /protein_id="HCR9914914.1"
                     /translation="MIDLYYAPTPNGHKIMLFLEEAELAYRLLKVDISKGNQFRPDFL
                     AISPNNKIPAIVDHAPADGGQPLSLFESGEILLYLAEKSGKLLSGELRERHTTLQWLF
                     WQVGGLGPMLGQNHHFNHFAPQAIPYAIERYQVETQRLYNVLNKRLETSPWLGGDHYS
                     IADIASWPWVNAHQRQRIDLDTYPAVYNWFERIRTRPATARALLQAQLHCNSTKA"
     gene            12511..13155
                     /gene="yfcF"
                     /locus_tag="OPV72_002660"
     CDS             12511..13155
                     /gene="yfcF"
                     /locus_tag="OPV72_002660"
                     /EC_number="2.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione transferase"
                     /protein_id="HCR9914915.1"
                     /translation="MSKPVIVLWSDANFFSPYVLSAWVALQEKGLSFTLKTRDLDQGE
                     HLQPGWRGYALTQRVPVLEADNFELSESSAIAEYLEERFAPPQWERIYPHDLQKRARA
                     RQIQAWLRSDLLPLREERPTDVVFAGAKKAPLSEAGKASAAKLFATAEALLGQGTQNL
                     FGEWCIADTDLALMINRLVLHGDDVPASLAAYATFQWQRASVQRFIALSSKRSG"
     gene            13211..13762
                     /gene="yfcE"
                     /locus_tag="OPV72_002661"
     CDS             13211..13762
                     /gene="yfcE"
                     /locus_tag="OPV72_002661"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase"
                     /protein_id="HCR9914916.1"
                     /translation="MKLMFASDIHGSLPATERVLERFAQSGARWLVILGDVLNHGPRN
                     ALPEGYAPAQVAERLNAVATQIIAVRGNCDSEVDQMLLHFPITAPWQQILTQERRLFL
                     THGHLFGPTNLPALHTGDVLVYGHTHLPVAQQQEGLYHFNPGSVSIPKGGYAASYGIL
                     DDNVLSVIALNDQSIIAQVAINS"
     gene            13819..14373
                     /gene="yfcD"
                     /locus_tag="OPV72_002662"
     CDS             13819..14373
                     /gene="yfcD"
                     /locus_tag="OPV72_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase YfcD"
                     /protein_id="HCR9914917.1"
                     /translation="MVEQRRLASTEWVDIVNEDNEVIAQSSREQMRAQRLRHRATYIV
                     VHDGMGKILVQRRTETKDFLPGMLDATAGGVVQADEQLLESARREAEEELGIAGVPFA
                     EHGLFYFEDQHCRVWGALFSCVSHGPFALQEDEVSEVCWLTPEEITARCDEFTPDSLK
                     ALALWMTRNAKNEAALQEKPEETE"
     gene            complement(14379..15398)
                     /locus_tag="OPV72_002663"
     CDS             complement(14379..15398)
                     /locus_tag="OPV72_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCR9914918.1"
                     /translation="MSIPRKRRSTGKVTIADVAQLAGVGTMTVSRALRTPEQVSDKLR
                     EKIEAAVHELGYMPNLAASALASASSHTIAMVVPNLAEAGCSEMFAGLQQILQPAGYQ
                     IMLAESQHRVEQEEKLLETLLASNIAAAILLSVEHSTTVRQWLKNASIPVMEMGAIRS
                     DPIDMNIGIDNVAAMYELTEMLIQRGYQNIGLLCANQEQWIFQQHLHGWYKAMLRHHM
                     SPNRVINAALPPNFSTGASQLPEFLLAWPELDALVCVSDELACGALYECQRRRIKVPD
                     DLAVVGFGDSDVSRVCQPPLTTMAVPHRKIGSEAGRALLERLNQGNWSDRKSIASSLC
                     MRESC"
     gene            15651..16094
                     /locus_tag="OPV72_002664"
     CDS             15651..16094
                     /locus_tag="OPV72_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCR9914919.1"
                     /translation="MLGTWLSDATITLRESVETWPQALEICGKPLLDAGVIAPEYITA
                     IVQQHQKLGPYYVLAPGLAMPHARPEEGAKGLGLSLLKLQRGVSFGADEFDPVDIIIM
                     LAAPDKHSHIEMISALAELFSSDVDMEKLHQAKNLEDIKTIIDRF"
BASE COUNT         3717 a         3944 c         4478 g         4049 t
ORIGIN      
        1 atgagaaaca gcttattttt ataaataatt gattattttg ataaaaaata gtggcatgcc
       61 ttttgcttta tccctgtaaa gaatgcggat ttttaccata aacattaagc agagggcgtt
      121 atgactgact cgattatgca gaattacaac cagctacgtg agcaggtaat caacggcgat
      181 cgccgtttcc agcacaaaga cggtcatttg tgttttgaag gggtcgatct ggacgctctg
      241 gcgcgccagt accccacgcc gttctatgtg ttttctgagc cggagattat tcgtaacatt
      301 catgaaatcc agcaggcatt tgcggcgcat aaaaatacca aaaccttctt tgcgtcaaaa
      361 acctgctcgg tcatgggggt gttgaaagcc attcgtgacg ccggaatttg cgcggaggca
      421 aactcacaat atgaggttcg caagtgcctg gagataggct ttcgcggcga tcagatcgtc
      481 ttcaacggcg tggtgaaaaa gcctgccgat ctggaatatg ccatcgccaa cgatctgtat
      541 cttattaatg ttgatagcct gtatgagctg gaacatattg atgccatctc tcgcaagctg
      601 aagaaagtcg ccaatgtttg cgtccgcgta gagccgaatg ttccctcggc gacgcatgcg
      661 gaactggtta ccgctttcca tgcgaagtcg ggtctcgacc tggaacaggc ggaagaaacc
      721 tgccgccgca ttctggcgat gccttatgtg catttacgcg gcttgcatat gcatgtgggc
      781 gatcaggtgc cggagtcaga gcctttcgca aaagcgacta aagtgctggt ggatgaatcc
      841 cgtcgcctgg aagaggtgct cggtattaaa tttgatttga tcaacgtggg cggcggaatt
      901 ccggttccct ataaatatga cgacgagaat ggcgacccgt taaaagataa tatgtatgcc
      961 ggtattaccg cccaggattt tgccgatgcg gtcattcgcg aagtgcataa atggcgtacc
     1021 gatgtggaaa tatgtattga accgggacgt aaagtgaccg ggtcggcggc ggttttactg
     1081 acggaagtct cctgcgaaaa acgtaaaaca aattacgatc ttaacggcaa tgtggaatgc
     1141 cacgttgaat ggaaatttgt cgatgctggt tacagcgtac tctctgatag ccagcatttt
     1201 gactggttct tttatgtcta taacgcctct cgcatgacgg cagcgcacga cgcctggata
     1261 aaattagccg ggccgctgtg tgatggcggg gattatttcc acatgggagt gaaaggcgaa
     1321 gagtttttac tgccgaagga gactcatgtt ggcgatattg tcgcgtttct tgatgccggg
     1381 gcatacacca ttgaaagtca aaccgtttat aacaaccgtc cgcgcacggg ggtggtgatg
     1441 atcgataaaa atggtgagac gcgtctgatt cgtcgggaag acagttacga agatatggtc
     1501 aagtacgaca tttattaata ctgttttggg cttcagtttc atgctgaagc ccgtcgtcag
     1561 atgataagaa gagggcagtg atgcctgaat gcataacagg agatggccat gagtaacacg
     1621 aattctggct tacttggcat caaagacatt gtctttatga atgtcatcgc tattctgagt
     1681 ttgcggcaaa tccctaacgt ggcgccttac ggggcatcgg ccatgttgct atgggtgata
     1741 gccgcattct gcttgttttt tcctttagcg atggtatgcg gcgagctgtc aaccggctgg
     1801 ccgaaagatg gcgggatatt tgtctggatt aaagaggcat ttggtaaacg tattgcatgg
     1861 attgtcgtgg tttgttttct cttttcctgc gtactgtttt tcccattaat gctgcaattc
     1921 ggctttaccg cgttgggcta tatgatcggc ggcggcctgg cggaaaataa agcgtttatc
     1981 ggtattggtt ccgcggtaat tttctggcta ttaacgctga tgaatatccg cgggatggaa
     2041 tggacaaaaa ttattaatag catcagcgcc tggtgcggcg tatttattcc ctccgccatc
     2101 ctcattttgc tggcggtggt atggctatgt accggacacc agatgcagac ggactacact
     2161 acagcgaaaa actggattcc ggatctcgga cactgggata cgatcgtttt cttatccagc
     2221 atgatgtttg cgtttgccgg actggaggtc gccccgatga ttgccgggcg tacccgtaat
     2281 ccacagcgtg attttccgcg agcgatggcc gtctctgccg ccgttatcgt tgggatctat
     2341 atggtcggca cctgggcgct aaatacgctt ttacccgccg ggaaaaccga catcgtggca
     2401 ggcgtcatgc aggctatgca tgctgctgcg gacacgctgc atatgccgtg gttaattcct
     2461 gttatggcca tctgtatgtt ttttggcgct ctcgggcaga ttaactcctg gctggtgggg
     2521 ccgatttata tgctccagga agcctcgcgt gaagataatc tgctggggga ccgaatcggc
     2581 aaattacatc cggtgtggaa aacgcccgcc tttgccttga ctatacaggc gattattgtc
     2641 acggtcctgt gtttttcgac ttttatttcg ccaagcgttg cggcggctta ctggatgtta
     2701 acggcgctaa cgaccatcac ctattttatt ccttatctgg tgatgttccc ggcgttctgg
     2761 cgtttacgta agactcagcc agatacgcca agaagtttta aaattccggg caaggtttta
     2821 ccggctattt tacccgcgct gggctttctt tctatcgcct ttgccgttgc gctgttattt
     2881 attccgcctt ctcaaattga tatgggcgga tatttccagt acgccgggaa aattattggc
     2941 ggagccgtgc tggcggttgt cgtcgcggag tacatttacc atcgggcgca gaaacgtaat
     3001 gcccgtttaa gcatggcggg aggaaaataa aatgtatatg ccagttctgg aaataaatct
     3061 acgcaagctg gaagaaaacg cacgcacgga aaaagctctg ctggcaagca gcggtattga
     3121 cgtgatggct gtcaataaag tttttgacgg ctgcgtggaa accgcgcagg cggtgttaaa
     3181 cggcggaatt accgttattg ctgaatcacg aacctataat ttgaaaaaaa tacgcgagac
     3241 aggatgtacg acctgcctgt tacgcagccc gtgtctgagt gaaatcgaag atgtggtgcg
     3301 ctacgcggat attagtttaa atagcgagcc ggtggtatta cgggcattat cgcaagaagc
     3361 ccaacgccag gggaaaacgc atcaggtatt actgatggtg gatatgggcg atttacgcga
     3421 gggtatctgg tttggtgaat atcaacgcat tcttgagacc gtgactctga ttactggtct
     3481 gcccggtctg gaattatatg gactgggcac caactttaat tgttacggca ccgtgttgcc
     3541 aacggtaaaa aatggcgagg attttctggc gctggccgcc cggctggaag ctgacagcgg
     3601 tattcctgtc cggcggcttt ctgcgggaaa ctgcaccagc tatcacctgc tggataaagg
     3661 tatctggccg cagggactga atcatctgcg catcggcgga ctgcatgaat tcggcattga
     3721 atatgtggac atgaaatacc tgaatgaatt tcaccactcc gcaaaaccgg tcgataaagc
     3781 ctgttccgat atgtatatcc tggaagcgga aatcatcgaa ctgaacagta aaccgaccgt
     3841 cccggtcggg gagctgggcg tcgatgcctt tttgcaaagt aaaacctttg tcgatcgtgg
     3901 catacgccga cgcgcattgc tggcgtttgg tcgtcaggat gtgccgtcgg ataactgtgt
     3961 gccatgcgac gacgctatca ctatcttagg gcaaaccagc gatcatacgc tggtggatat
     4021 tgaagattgt cgtcagtcgc taaaagtagg cgatgtggtt cgctttgagc tggattatac
     4081 gggcctgtta atggcctgcc agaccaaagg cgtcgcctgg aggtttacgc gttaacgcat
     4141 aaccgccgcg gctatgtcgc ggcggcatct ttgacctcac gaaagacagg gagtaacgat
     4201 ggataccctg caacaatctc cgccagcaga gcctgaaggc ggtctgcggc gtaacctgaa
     4261 gaagcggcac ctgctgatga tgtcgctggg cggcacgatt ggcaccggct tatttatcgg
     4321 cattgccgaa ccgttaagca gcgtcgggcc ggcgggaacc ttactggcct atctgtttgc
     4381 cggaaccatt atgctggcga cgatgatgtg tcttggcgaa ttatcatgcg cctttcctca
     4441 ctccggttca tttcaacatt acgcgctgat gtttatgccg tcaccttgct ggagctatac
     4501 cattggctgg ctttactggt ttagctgggt cttttccctg gcagccgacc tcactgccgc
     4561 agggtttatt gctcaccagt ttttccccgc ggttccggta tatatgttct gcctggcgat
     4621 tctgctcatc ctgacggcta tcaatctcac ctccgcaaaa agttttggcg aatgcgaata
     4681 ctggctttcg gccattaagg tcttcgcgat cgtgctgttt atctgcgcgg gcggggtcat
     4741 gatctactcg ctaatgggcc atagtgactg gcacccgacg ttaaaaacag acggaatgtg
     4801 gtttccccac ggttgggagc aaattgtggt ctgtatgacg atcgtgattt actccttcca
     4861 gggggtggaa ctggtcggaa atgcggcagg ggagaccgaa tcgccgcaca ttattttacc
     4921 gaaggtgatc ctggggatcg gtctcagaat cattttgttt tacggcctgg cgattgcggt
     4981 gctggcgctg gtctatccgc atgaactgac gccaaatgga caaagtccct ttgtatgggt
     5041 attctcccac gcgggcattc cgggggcgga tacgctgatg acgctggtga tcttttccgc
     5101 cgcggtttct gccgctaact cggccattta cgccagttcg cgtatgctgt ggtctatggc
     5161 gggcgatcgc tttgcgccag cctgctttgg taaaacgaac ggcggcggcg tgccggtgta
     5221 tgctatttta atcacggcct tgctggcgtt ggtgtcgttg ctgacccgct atattcccgc
     5281 acagcaattt tatttatatc tgatcgccag taccgggcag gtgggttgcc tggcatggat
     5341 aaccatcgga tggtgccagt atcgcttccg acaatcggtg cgtaatggca cgtacgccag
     5401 cgatttgcta cgctatcgat cgccgctttt tccctggacg gcccgatttg tcattatcac
     5461 caattttgcc attatggtcg gcacctagtt tagtgagcag ggagtagtga taatgttggt
     5521 tgagctggct tttatgatag ggattctttt gtcatggtat ctcttcagac ccactttgag
     5581 ccggttacgt aacacagtgg gatgaacggc gctcgtaaac ggtaagagga catgaaacga
     5641 ctcattgtag gtattagcgg cgccagcgga gcgatttatg gcgtgcgctt attacaaatt
     5701 ttgcgcgatg tcgatagcgt ggaaacgcat ctggtgatga gccaggcggc ccggcaaacg
     5761 ctggcgctgg agacccattt ttcgctgcgc gaggtgcagg cgctggccga tgtgacgcac
     5821 gatgcgcgcg acattgccgc cagcatttcc tccggctctt acccgacggc aggaatggtt
     5881 atcctgccct gttcgattaa aacgctgtcg gggattgtcc acagttatac tgacggactg
     5941 cttacccgcg cggcggatgt gatattaaaa gagcggcgac ctctggtgct gtgtgtgcgc
     6001 gaaacgccgc tgcatatcgg gcatttgcgt ttaatgaccc aggccgctga gataggcgcg
     6061 gtgattatgc cgccggttcc ggctttttat caccttcctc agacgttaga tgatgttata
     6121 aatcaaacgg ttaaccgagt gttggatcaa tttgacatcc cccttccgca cgaccttttt
     6181 gttcgctggc agggcgcata gcgttgtctg tttagcgtgc attattgtcc ctgttgccct
     6241 gtttcagggc aattttgtaa ccgcgatcat atcctcaaca tttaattcgt taaaagccgc
     6301 cgaaacgctg cggttcaacc gtcatacctg ctatcttcaa catcaggaca atattgcaac
     6361 gttttattaa caaatttaac gtcgaatcgt tttgctgacg tgaaaatggc ataagacctg
     6421 catgaaaaag tctgcaaaca cacaacgcca cgtaaaacat aagaaaatga cgccacttga
     6481 ggggtatgta tgaagaagac cgttctcgct ttgtctttgc tgataggtct gggcgcgacg
     6541 gcggccagtt acgccgcgct cccgcaaacg gttcgtattg gaacagatac cacctacgcg
     6601 cctttctcat cgaaagatgc caaaggcgac tttattggct ttgatatcga tctcggtaat
     6661 gaaatgtgta agcgtatgca ggtgaaatgt acctgggtcg ccagcgactt tgatgcgctt
     6721 attccctcac taaaagcgaa aaaaatcgat gccattattt catcgctctc tattaccgat
     6781 aaacgccagc aagaaattgc gttttccgac aaactttacg cggcggattc acgcctgatt
     6841 gcggcaaaag ggtctcccat tcagccgacg ctggaatcgc tgaaaggcaa gcatgtcggc
     6901 gtgctgcaag ggtccacgca agaggcttac gccaatgata actggcgcac taaaggtgtg
     6961 gatgtggtgg cttatgccaa ccaggatctt atctattccg atttaaccgc cggtcgtctg
     7021 gatgccgcat tgcaggatga agtcgccgcc agcgaaggtt tcctgaagca gccagcgggc
     7081 aaagagtatg cgtttgccgg tccttccgtg aaggataaaa aatattttgg cgacgggacg
     7141 ggggttgggc tgcgcaaaga cgataccgag ctaaaagccg cgtttgataa agcgctgacc
     7201 gaactgcgcc aggacggaac ttacgacaaa atggccaaaa agtacttcga ttttaatgtc
     7261 tacggcgatt gagggaaggg gataacgcgc cgcgctgggg aactatcacg gtgcaaaata
     7321 gatgttttgc acctttttgg tgcataagcc gttgcggaac aggcgcataa atgcatactt
     7381 aatcgatttt tatgcaaaat aaaccggctg acaaggtaga atgctttgcc ttgtcggcct
     7441 gattaatggc acgatagtcg catcggatct gtaaagatct cctggaaaga cagtctgttg
     7501 aggatagtta tgaaaaaact ggcgttatcc ctttctctgg tgctggcatt ttccagcgct
     7561 accgcagcat ttgccgctat tccacaaaag attcgcatcg gtaccgatcc tacatacgca
     7621 ccgtttgaat ccaaaaatgc acaaggtgaa ttggtcggct ttgatatcga tctggccaaa
     7681 gaactgtgca accgtatcaa cacacagtgt acgttcgtgg aaaacccgct ggatgcgctg
     7741 attccgtctt taaaagcgaa gaaaattgat gccatcatgt cctcgctgtc catcactgaa
     7801 aagcgccagc aggaaatcgc gtttaccgac aagctttacg ccgctgattc ccgtctggtg
     7861 gtggcgaaga actctgatat tcagccgacc gtcgcgtcgc tgaaaggcaa gcgcgtcggc
     7921 gtgctacagg ggacgacgca ggagaccttc ggcaatgagc actgggcgcc gaaagggatt
     7981 gagatcgtct cttaccaggg gcaggacaac atttattccg acctgacggc tggccgtatt
     8041 gatgcggcgt tccaggacga ggtcgcggcc agcgaaggtt tccttaaaca gcccatcgga
     8101 aaagactata aattcggcgg cccggcggtg aaagatgaga agttattcgg cgtaggaacc
     8161 ggtatggggc tgcgcaaaga ggataacgag ctgcgcgaag cgctgaacaa agcctttgct
     8221 gaaatgcgtg ctgacggtac ttacgaaaag ttggcgaaaa agtactttga ttttgatgtt
     8281 tatggcggtt aatcaccgtc ggtgcagata aagcccaaag aatattgact gtctgcattg
     8341 cctgagggcg ctgtgcgcgt caggcctacg gggagcatcg taggccgggc aaggcacagc
     8401 cgccatccgg cgtgatgtga ggcaaaaatg caaaagaggc ttcttacttc accacacaca
     8461 acaggacagg ctgcatgttg tacgggtttt caggcgtaat tttacagggc gcgatcgtca
     8521 cgctggaact ggcgctcagt tccgtggtgc tggccgtgct tatcggtctc gtcggcgcgg
     8581 gggcgaagct ttcgcaaaac cgggtaacgg ggcttatttt tgaagggtac accaccctga
     8641 ttcgcggggt gccggatctg gtattaatgc tgctgatatt ttacggattg caaatcgcgc
     8701 ttaacgtggt gaccgattcg ctgggtatcg accagataga tattgatccg atggtggccg
     8761 gtattatcac ccttggtttc atctacggcg cctattttac cgaaaccttt cgcggcgcgt
     8821 ttatggcggt accgaaaggc catatcgagg cggcgacggc ctttggtttt acccacgggc
     8881 aaaccttccg gcggattatg ttcccggcga tgatgcgtta cgccctgccg gggatcggca
     8941 ataactggca ggtgatactc aaagcgacag cgctggtgtc gctgctgggc ctggaagatg
     9001 tcgtcaaagc cacgcagctt gccggtaaaa gcacctggga gcctttctat tttgccgtgg
     9061 tctgtggact tatctacctg gtatttacca ccgtttccaa tggtgtgctg ctcttacttg
     9121 agcgtcgcta ttccgtaggc gtgaagaggg ccgatttgtg attgagatca ttcaggagta
     9181 ctggaaatcc ctgctgtgga cggatggcta tcgttttaca ggcgtggcga ttacgctgtg
     9241 gttgttaatt tcatcggtgg tgatgggcgg tcttctggcg gtgattctgg cggtgggtcg
     9301 cgtttccagt aataaattca tccgttttcc catctggctg tttacgtata tttttcgcgg
     9361 cacgccgctg tacgtacagc tactggtgtt ctattcgggg atgtatacgc tggagatagt
     9421 caaaggcacc gatcttctta acgcgttttt ccgcagcgga ctgaactgta ccgtactggc
     9481 gctgacgctg aatacctgcg catacactac ggagattttc gccggagcga ttcgttcggt
     9541 accgcacggt gaaattgaag cggcaagagc gtatggcttc tcgtcattta aaatgtatcg
     9601 ctgcattatt ttgccgtcgg cattacgcat cgccttgcct gcctacagca acgaagtgat
     9661 tttaatgctg cactctacgg cgctggcgtt taccgcgacg gtgccggatt tgttgaaaat
     9721 cgcccgcgat attaactcag cgacttacca gccgtttacc gcgtttggca ttgccgccgt
     9781 gttgtattta ctcatttcgt atgtcctgat aagcctgttc cgccgggcgg aaagacgctg
     9841 gttgcagcac gtgtcctcta aataattcga gtaacatgat gtcagaaaat aaattacacg
     9901 ttatcgattt gcacaaacgc tacggcggtc atgaagtgct gaaaggggta tcgctgcagg
     9961 cccgcgccgg agatgtgatt agcattatcg gctcgtccgg ttccggtaaa agcacttttt
    10021 tgcgctgcat taacttcctc gaaaaatcga gcgaaggcgc gattatcgtg aacggtcaga
    10081 acattaatct ggtgcgcgac aaagacgggc agctcaaagt ggcggataaa aatcagctac
    10141 gcttgttgcg tacccgcctg acgatggtgt ttcagcactt taacctctgg aaccacatga
    10201 cggtgctgga aaatgtgatg gaagcgccga ttcaggtact gggattaagc aagcacgacg
    10261 cgcgcgagcg ggcgttgaaa tatctggcga aggtggggat tgatgagcgc gctcagggca
    10321 aatatcccgt ccatctctcc ggcggccaac agcagcgcgt ttctattgcg cgcgcgctgg
    10381 cgatggaacc tgacgtttta ctgttcgatg aacccacatc ggcgctcgat cctgaactgg
    10441 tcggcgaagt gttgcgcatc atgcaacaac tggcggaaga aggcaaaacg atggtggtgg
    10501 tcacgcatga aatgggcttc gcccgccatg tctcttcgca cgtgattttt ctgcatcagg
    10561 ggaaaattga agaagagggc aatccggagc aggtgttcgg caatccgcaa agcccgcgtt
    10621 tacagcaatt cctgaaaggc tcgctgaaat aaaagaagcc cggcggcgca tcgcttaccg
    10681 ggcaggatac ggcgctttgg gaattagcga atcacatccg ccagcgcctc ttctaaatca
    10741 taccagcgaa atgcgaatcc ggcggcttca agccgttttg gcagcgcccg ctgtccgccc
    10801 agtaccagca ctgacgactc tcccatcaat aagcgaattg ccgtcgccgg aatgcgaata
    10861 atcgccgggc ggcgcagcgc gcgacccagc gcatgagcaa actgctcatt atggacggga
    10921 tacggcgaga ccatattgaa gggaccgcga agatcgttat ccagcagcca caggatgccg
    10981 ttgaccatat cgtcaatgtg aatccaggcc agatattgcc gaccattacc caccggaccg
    11041 ccgagtccga ggcgaaacgg cggaaccatt ttccccagaa tcccgccttg cggcgccagg
    11101 acaacgccgg tacgcagcag gcagacgcgg gtctggtcgc tctgcgcacg acaggcaatc
    11161 tgttcccagc gggcgcaaag tttatgcgta aattcgttgt gcggcggctc atcttcagtg
    11221 acgacaacgt cgcccagatc gccgtaatag cccgtggcgg agccggatat caacaccgag
    11281 ggcggcgtag cgctggcatg aattaaatcc accaactttt gcgtgatagc ccagcggctt
    11341 tggcacaacc gttctttttg ttgcgacgtc cagcgcttgt cggcaatcgg ttcgcccgcc
    11401 agattgatga tggcatcaat ctcattgagg tgctcacgtt ccgccagccc tttccataat
    11461 gtcactctgg aatcgagaat ctgacgcgcg ttatcgggat tgcgcgtaac gaccgtcacc
    11521 tggtgcccca gtattaacag ccggggaatg agatgacgcc ctatcaggcc cgtaccgccg
    11581 gtaatcagaa tctgcatatg acctccagag tagggaggat ttcctcttcc ctaatgtcag
    11641 gtttttaata cgaataaggg tgccggacgc aggttttccg tgtatacacc tctacatcat
    11701 acatgatgta tgctaccgcg ttacgctttc gtactgttac agtgcagttg cgcttgtaac
    11761 agtgcgcgcg ctgtcgcagg acgcgtgcga atgcgttcaa accagttata caccgccggg
    11821 taagtatcaa gatcgattcg ctgacgctga tgtgcgttaa cccacggcca actggcgata
    11881 tccgcaatac tgtagtggtc gccgcccagc cacggggagg tttccaggcg tttattcagg
    11941 acgttgtata agcgttgcgt ttcaacctga tagcgttcaa tcgcataggg gatggcctgt
    12001 ggcgcaaagt ggttaaagtg atgattctgg cccagcatcg gccctaaccc gccgacctgc
    12061 cagaacagcc attgcagcgt ggtatggcgt tcacgcagct ccccgctaag cagtttgccg
    12121 cttttttccg ctaggtagag aagaatttcg ccggattcaa aaagactaag cggttgaccg
    12181 ccgtctgccg gggcgtgatc gacgatggca ggaattttat tattgggaga gatagccaaa
    12241 aaatcagggc gaaactgatt gcccttgctg atatctactt ttagcaaacg atacgccagc
    12301 tccgcctctt ccagaaacag cattatttta tgcccgttgg gcgtgggggc gtagtaaagg
    12361 tcaatcattt tggctcctgc atgtgcgtaa agagtctggg ctgaattaag tatagaaagc
    12421 ctcctgatgt gtgtgagttt tcatcaggtg acagcaggcg aaagacgcta tattttggga
    12481 agaaacctaa tacgccctca agaggacatt atgagtaagc ctgttattgt gctgtggtcg
    12541 gatgcgaact ttttctctcc ctacgtcttg tccgcctggg tggcattaca agaaaaaggg
    12601 ctttccttta ctctgaaaac ccgcgatctg gaccagggag aacatctgca acctggctgg
    12661 cggggatatg cgctgacgca gcgcgtcccg gtgcttgagg ccgacaattt tgagctgagc
    12721 gagtcgtccg ctattgcgga atacctggag gagcgtttcg cgccgccgca gtgggagcgt
    12781 atctacccgc acgatttaca aaaacgcgcc cgcgcgcgac agattcaggc gtggctacgc
    12841 agcgatttac tgccgcttcg cgaagaacgg cctaccgacg tggtgtttgc cggggcgaaa
    12901 aaagcgccgc taagcgaggc tggaaaagcc agtgcggcaa aactgtttgc gacggctgaa
    12961 gcgctattgg ggcaggggac gcaaaattta tttggtgaat ggtgcattgc cgataccgat
    13021 ctggcattga tgatcaatcg tctggtgctg catggcgatg acgtgccggc gtcgctggcg
    13081 gcgtatgcga catttcagtg gcagcgtgct tccgtacagc gttttattgc gctttcctcg
    13141 aagcgttcag gctgaaaatc tattcatatt ccagtatcat aacgccgttt ttcacaatga
    13201 ggagtgagcg atgaaactga tgttcgcatc ggacattcat ggttctttac ccgccacgga
    13261 acgcgtgctt gagcggttcg cgcaaagcgg cgcgcgttgg ctggtgatat taggcgatgt
    13321 ccttaaccac gggccgcgca atgcgctgcc tgaaggctat gcgcccgccc aggttgccga
    13381 acgcctgaac gcggtggcga cgcaaatcat tgccgtgcgc ggcaactgcg atagcgaagt
    13441 ggatcagatg ctgctgcatt tcccgataac tgcaccgtgg cagcaaatat tgacgcaaga
    13501 gaggcggcta tttttaacgc atgggcacct cttcgggccg acgaatctgc ccgctctgca
    13561 tactggcgat gtgttggtct atggtcatac gcatctgccg gtggcgcaac agcaggaagg
    13621 actgtatcac tttaatcctg ggtcagtgag catcccgaaa ggcgggtatg cagcaagcta
    13681 cggtattctg gatgataatg tgttgagcgt aatcgcactc aatgatcaaa gtatcattgc
    13741 gcaggttgca attaactcgt aatttacctc acaaacgtaa atgcgccgta agagcgccag
    13801 aaataagaag gtttcctgat ggtggaacag cgtcgtttgg caagtacgga atgggtggat
    13861 attgtgaatg aagacaatga agtcattgca cagtccagcc gggaacagat gcgtgcgcaa
    13921 cgcttacggc atcgtgcgac gtatatcgtc gttcatgatg gtatgggtaa aattctggtg
    13981 cagcgtcgta ccgaaacaaa agattttttg cccggtatgt tagatgctac cgcaggcggc
    14041 gtggtccagg ctgatgagca gctactggaa tctgcccgcc gcgaagcgga agaagagttg
    14101 ggtattgcag gcgtgccgtt tgccgaacac ggtctgtttt actttgaaga ccaacattgc
    14161 cgggtttggg gcgcgctgtt tagctgcgtt tcccacgggc ctttcgcgct tcaggaagat
    14221 gaagtcagcg aagtgtgttg gctgactccg gaggagatca ccgcgcgctg tgatgaattt
    14281 acgccggact cgctcaaagc gctggcgctg tggatgaccc gcaacgccaa aaacgaagcc
    14341 gcgcttcagg agaaaccgga agagacggaa taagcgtttt agcagctttc ccgcatacat
    14401 aaactggagg cgatagattt tcgatcgctc cagtttccct gatttaacct ttccaacagc
    14461 gcccgtccgg cttcactgcc aatcttacgg tgcggtacgg ccatggtggt taacggcggc
    14521 tggcagaccc ggctgacatc gctatcgcca aacccgacca ccgctaaatc gtccggaact
    14581 ttgatccgcc gtcgttggca ctcgtataac gcgccgcagg ccagctcatc cgatacgcat
    14641 accagcgcgt ccagctccgg ccatgctagt aaaaactccg gcagttgcga cgcgccggta
    14701 gaaaaattgg gcggcaaggc ggcattaatc acccggtttg gcgacatatg gtggcgaagc
    14761 atcgctttgt accagccgtg cagatgttgc tgaaaaatcc actgctcctg attggcgcat
    14821 agcagcccga tattctggta accgcgctga atcagcattt ccgtcagctc atacattgct
    14881 gcaacgttat caataccgat attcatatca ataggatcgc tgcgaatcgc gcccatctcc
    14941 atcaccggga tagaggcatt tttcagccac tggcgcacgg tagtgctatg ttcgacgcta
    15001 agcagaatcg ccgcggcaat gttggaagcc agcagcgttt cgagcagctt ctcctcttgt
    15061 tccacgcgat gctgcgattc cgccagcatt atctggtagc ctgcgggctg taaaatttgt
    15121 tgcagcccgg cgaacatttc agaacacccc gcttccgcaa ggttcggtac gaccatcgcg
    15181 atggtgtgcg aggaggcaga cgccagcgcg ctggcggcga gattaggcat atagcccagc
    15241 tcatgcactg ccgcttcgat tttttcccgg agtttatcag agacctgttc cggcgtgcgt
    15301 aaggctcgtg atacggtcat cgtgcctaca ccggcaagtt gggctacatc ggcgatagtc
    15361 actttaccgg tactgcgccg tttacggggt atcgacatac aaattcctgc gtcattacaa
    15421 catgttgaga tgctttttta ttgtcgttct ttgcttcgca tgactggcag tatacgcctt
    15481 aaatccgctt ttttgctgtg atttcacacc atgattttaa tttgatagcg ctatcacaat
    15541 tctgagtaat agtcgctggt agcgctatct ttgtgataac gatcgcagct aatatcgaat
    15601 ggcttgaata aagtttgttc ataatttcat acaccgtggg ggcgaataac atgctgggaa
    15661 cctggttatc tgacgcaacc atcacgctac gggagagcgt ggaaacgtgg ccgcaggcgc
    15721 tggaaatttg cggcaaaccc ctgctggacg caggtgttat cgcaccggaa tacattacgg
    15781 cgattgttca gcagcaccaa aagcttgggc cgtattatgt attagcgcca gggttagcga
    15841 tgccgcatgc gaggccggaa gagggggcga aagggttagg tttatcgtta ctgaaactac
    15901 agcgcggcgt ttcatttggc gcagacgaat tcgatccggt tgacatcatt attatgctgg
    15961 cggcgcctga taagcacagt catatcgaaa tgatatcggc tctggcggaa ttattttcca
    16021 gtgatgtaga tatggaaaaa ttacatcagg caaaaaacct ggaggacatt aaaacgatta
    16081 ttgaccgttt ctgattttat tccattttct tgcggtaaat aacattgcgc ccgtgcgtga
    16141 tgcagaccaa ctctactttt aaaaggtgac aataatgaaa atcatggc
//
LOCUS       DAJVBX010000100        16027 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.100, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000100 DAJVBX010000000
VERSION     DAJVBX010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 16027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16027
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.100"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            111..1013
                     /gene="tagK"
                     /locus_tag="OPV72_002665"
     CDS             111..1013
                     /gene="tagK"
                     /locus_tag="OPV72_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system-associated protein
                     TagK"
                     /protein_id="HCR9914920.1"
                     /translation="MKQDMWELRKIQSQGITDNAQYPAGTYIVFTAAAPYIPLFEQHG
                     KDDIALSLVRHEEAWWIVNHSDELCCAVNEQVMEPHHRMRLNDGDTIEWGLSSWCLAR
                     TNDESRPDVSFPQLVQSSESVAEYLDLDWFKQQQLNPQNPFDIIPVRETAPSYTGHEA
                     DSTLHQLYQEYQQALRPSGQEKPLRPKPFPRNEDAVTQDLTSLYDKKGDTDTLQDMVA
                     GAPGIDAILDTLDTTGEGEMHWLAMESMPDILQLLSPEMGGKTAHSEILPDLTRREHR
                     IIGIDSHYRITPTQKNGNTAHEKN"
     gene            1000..1824
                     /locus_tag="OPV72_002666"
     CDS             1000..1824
                     /locus_tag="OPV72_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="impE family protein"
                     /protein_id="HCR9914921.1"
                     /translation="MKKTDTLPATLSALLQEYSIAEGIQMAEQQVRENPAKALCRHSL
                     FQLLCVAGDWARALHQLQLCARMEANYTQEARLYRELVCCEMFRHTVFQGEQRPGFLL
                     PQPVWVESLLAALACHDDTGEVDKHRNTALEAITDTGGQWNGGAFDWASDSDSRLGPV
                     LELVTGGVYIWLPFSQIRSLESPQPTRLTDLLWKPVNITLVNGDTHGAWLFTRYSGSE
                     SASDALRLCRETAWQDGPGETTVRALGQKVWLTSHGDISLLDMTHCTFHAQENDGA"
     gene            1821..2315
                     /gene="tssE"
                     /locus_tag="OPV72_002667"
     CDS             1821..2315
                     /gene="tssE"
                     /locus_tag="OPV72_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssE"
                     /protein_id="HCR9914922.1"
                     /translation="MSTSRFTPANHLLPTLFDRLCDNAPYQKIDRDISVTPVQLKEII
                     RRDLSFLLNTISHEGDIDARRYPQAAASVLNYGLPPLAGSFMYEHKWDDISEAIRRAI
                     IRFEPRLNAATLRVTPLLDEARQGSYNTLQFEIRGQILTQPYPTEFLVRSALDMELSR
                     ITFF"
     gene            2331..4214
                     /gene="tssF"
                     /locus_tag="OPV72_002668"
     CDS             2331..4214
                     /gene="tssF"
                     /locus_tag="OPV72_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssF"
                     /protein_id="HCR9914923.1"
                     /translation="MDPRLLEYYNRELSYLRETGAEFATLHPKIAARLGMQGTDIADP
                     YVERMIEAFSFLSARTQLKIDAEFPRFTQRLLEVVNPNYVTPTPSMAVVKLYPDTQEG
                     DLAKGVTVPRDTAFVSPIPEGENTACQFRSSQDVTLWPLSIEEVRLTAAPPDMPALHR
                     YLPPNIHVAGALRITLRTFGELAFSELAGPARLPFYLCGEERIASHLFELLHTSAVAT
                     LAGEPGHFDGELNVNLQHPVAHEGLEPGQGLLPLAWNVFHGHNLLHEFFACPERFYFF
                     TPTGLSAGLQKVQGNVAEIVILLNRLPPDWLIHQTDAAQFSLFCTPVINLFPRTTTRI
                     EVTHSVTEQHLVVDRTRPLDYEVFSVQEVEGLEAETTRKMIFRPLYHTRNNDEGNHGR
                     YFSLRREPRRSSESARRYGTRTPYTGSEVFLSLVDQHEAPYPENLRHITVTAMVTNRD
                     LPCLIPRNGRDDLTVDAAIPVAGVGLIRPPRPPQPPLAEREMAWRLIRQLSFNYLPLA
                     DLDHRTGGQALRDLLNLFIPAHDSPQSRQVRSLIGCKTTPVTRRLPGSGLLVYGRGVS
                     CELTVDEEGFSGISPYLFGLVLEHYIARHVSINTFSQMTLHSMQRGHVMTWPVRTGQR
                     GSV"
     gene            4211..5206
                     /gene="tssG"
                     /locus_tag="OPV72_002669"
     CDS             4211..5206
                     /gene="tssG"
                     /locus_tag="OPV72_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssG"
                     /protein_id="HCR9914924.1"
                     /translation="MTGALDQAQKAPWRYGFLNLMRRVDAQLCDTPAGSIWQPRMEKF
                     RLGQTPTMTFAPREIAQVSWQDGRLHLSLYSLGLWGPNGPLPLHYTELALNRSESRHD
                     PTLVHFSNIFHYRWLTQFWQAWRSGQSAGGGLDKPEHDRFAFYIASISGQDLRESAES
                     PLSDHVRLAASAHLVRESRNPDGLAATLAHYFSVPFAVKEFALHWITVANDEITRLGT
                     PAQSSVLGNGALIGQAVPDMQYKFRLIIGPLTLEDYLRFLPGGNNLPVLTELVRTFIG
                     FEYCWEIELQLKPHAAPPAVIGGAQRLGWTAWAGKAMHDRPVTGMIFEPEHGLTH"
     gene            5217..6271
                     /locus_tag="OPV72_002670"
                     /pseudo
     CDS             5217..6271
                     /locus_tag="OPV72_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459263.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ImpA family type VI secretion system protein"
     gene            complement(6591..6667)
                     /locus_tag="OPV72_002671"
     tRNA            complement(6591..6667)
                     /locus_tag="OPV72_002671"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6631..6633),aa:Asp,seq:gtc)
     gene            complement(6801..7532)
                     /gene="dnaQ"
                     /locus_tag="OPV72_002672"
     CDS             complement(6801..7532)
                     /gene="dnaQ"
                     /locus_tag="OPV72_002672"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit epsilon"
                     /protein_id="HCR9914925.1"
                     /translation="MSTAITRQIVLDTETTGMNQIGAHYEGHKIIEIGAVEVINRRLT
                     GNNFHVYLKPDRLVDPEAFGVHGIADEFLLDKPVFADVVDEFLDYIRGAELVIHNASF
                     DIGFMDYEFGLLKRDIPKTNTFCKVTDSLALARKMFPGKRNSLDALCSRYEIDNSKRT
                     LHGALLDAQILAEVYLAMTGGQTSMTFAMEGETQRQQGEATIQRIVRQASRLRVVFAS
                     EEELAAHESRLDLVQKKGGSCLWRA"
     gene            7596..8063
                     /gene="rnhA"
                     /locus_tag="OPV72_002673"
     CDS             7596..8063
                     /gene="rnhA"
                     /locus_tag="OPV72_002673"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI"
                     /protein_id="HCR9914926.1"
                     /translation="MLKQVEIFTDGSCLGNPGPGGYGAILRYRGHEKTFSEGYTLTTN
                     NRMELMAAIVALEALKEHCEVTLSTDSQYVRQGITQWIHNWKKRGWKTAEKKPVKNVD
                     LWKRLDAALGQHQIKWVWVKGHAGHPENERCDELARAAAMNPTQEDSGYQAEA"
     gene            complement(8060..8782)
                     /locus_tag="OPV72_002674"
     CDS             complement(8060..8782)
                     /locus_tag="OPV72_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCR9914927.1"
                     /translation="MKPARLSQTVVAPGCWGELPWGNYYREALEQQLNPWFAKMYGFH
                     LLKIGNLSAEINSEACAVSHQVNVSSQGSPMQVLADPLHLPFADKSVDVCLLAHTLPW
                     CTDPHRLLREADRVLIDDGWLVISGFNPLSLMGLRKLVLVLRKTPPYNSRMFTLMRQL
                     DWLSLLNFEVLHYSRFHVLPWKKQGGRLLNTHIPALGCLQLIVARKRTIPLTLNPLRH
                     NKSKTPIRQTVGATRQYRKPDG"
     gene            8817..9572
                     /gene="gloB"
                     /locus_tag="OPV72_002675"
     CDS             8817..9572
                     /gene="gloB"
                     /locus_tag="OPV72_002675"
                     /EC_number="3.1.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacylglutathione hydrolase"
                     /protein_id="HCR9914928.1"
                     /translation="MNLNSIPAFQDNYIWVLTNDEGRCVIVDPGEAAPVLKAIAAHKW
                     MPEAIFLTHHHYDHVGGVKELLQHFPQMTVYGPAETQDKGATHLVGDGDTIRVLGEKF
                     TLFATPGHTLGHVCYFSHPYLFCGDTLFSGGCGRLFEGTPSQMYQSLMKINSLPDDTL
                     ICSAHEYTLANIKFALSILPHDSFINEYYRKVKELRVKKQMTLPVILKNERKINLFLR
                     TEDIDLINEINKETILQQPEARFAWLRSKKDTF"
     gene            9644..11011
                     /gene="mltD"
                     /locus_tag="OPV72_002676"
     CDS             9644..11011
                     /gene="mltD"
                     /locus_tag="OPV72_002676"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein transglycosylase D"
                     /protein_id="HCR9914929.1"
                     /translation="MKAKAILLASVLLVGCQTSQNTGNVQQHAQSLSAAGQGEAGKFT
                     SQARWMDDGTSIAPDQDLWAFIGDELKMGIPENSRIREQKQKYLRNKSYLHDVTLRAE
                     PYMYWIAGQVKKRNMPMELVLLPIVESAFDPHATSGANAAGIWQIIPSTGRNYGLKQT
                     RNYDARRDVVASTTAALDMMQRLNKMFDGDWLLTVAAYNSGEGRVMRAIKANKARGKP
                     TDFWSLSLPRETKLYVPKMLALSEILKNSKRYGVRLPTTDESRALARVRLNSPVEMAQ
                     VADMAGMSISKLKTFNAGVKGSTLGVSGPQYVMVPKKHAEQLRESLASGEIDAVQSQL
                     IADNTPLNSRSYKVRSGDTLSGIASRLGVSTKDLQQWNNLRGSRLKIGQSLTVGAGSS
                     AQRLANNSDSITYRVRKGDSLSSIARRHGVNIKDVMRWNHDTDNLQPGDQLTLFVKDN
                     STPDS"
     gene            complement(11067..11837)
                     /locus_tag="OPV72_002677"
     CDS             complement(11067..11837)
                     /locus_tag="OPV72_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCR9914930.1"
                     /translation="MTTHSHHDNVEKQFGSQANAYLHSAVHAAGRDLARLAQRLSDFS
                     HASVLDMGCGAGHASFVAAQHVNSVVAYDLSASMLEVVAGAAEERHLSNITLRQGYAE
                     KLPFEDASFEVVISRYSAHHWHDVGQALREVYRVLKPGGVLIIMDVMSPGHPVRDIWL
                     QTVEALRDTSHVRNYSSGEWLAMVNNAMLVTNTVITDRLSLEFRSWVTRMRTPAPLVE
                     AIRLYQASAPVEVKRYFELQDDGSFSSDTIMLEAHKAV"
     gene            complement(11915..12715)
                     /locus_tag="OPV72_002678"
     CDS             complement(11915..12715)
                     /locus_tag="OPV72_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HCR9914931.1"
                     /translation="MRKNTYAMRYVAGQPAERILPLGSFASIGQALPAGEPLSSEERI
                     RILVWNIFKQQRAEWLSVLKNYGKDAHLVLLQEAQTTPELVQFATANYLAADQVPAFV
                     LPQHPSGVMTLSAAHPVYCCPLREREPILRLAKSALVTVYPLPDTRLLMVVNVHAVNF
                     SLGVDVYSKQLLPIGDQIAHHSGPVIMAGDFNAWSRPRMNALYRFAREMSLRQVRFTD
                     DQRRRAFGRPLDFVFYRGLNVNEASVLVTRASDHNPLLVEFSPGKPEQ"
     gene            complement(12847..14022)
                     /locus_tag="OPV72_002679"
     CDS             complement(12847..14022)
                     /locus_tag="OPV72_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR9914932.1"
                     /translation="MPLALFALTISAFAIGTTEFVIVGLVPTIAQQLAVSLPSAGMLV
                     LIYALGVAIGAPVLTALTGRLPRKQLLVALMVLFTAGNLLAWQAPGYMTLIAARLLTG
                     LAHGVFFSIGSTIATSLVPKEKAASAIAIMFGGLTVALVTGVPLGTFIGQHFGWRETF
                     LAVSLLGVIALMSSQLLIPANIPGRAAASIRDQVKVLTHPRLLLIYAVTALGYGGVFT
                     AFTFLAPMMQDLAGFSPAAVSWILLGYGVSVAIGNIWGGKLADKHGAVPALKFIFAAL
                     FVLLMVFQVTASTQYAALATILVMGIFAFGNVPGLQVYVVQKAEQFTPNAVDVASGLN
                     IAAFNIGIALGSVIGGQTVAHYGLAQTPWIGALIVLVAFLLMGVSGRLDKPVRIALE"
     gene            14127..15041
                     /locus_tag="OPV72_002680"
     CDS             14127..15041
                     /locus_tag="OPV72_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCR9914933.1"
                     /translation="MKATSEELAIFVAVVESGSFSRAAEQLGQANSAVSRAVKKLEMK
                     LGVSLLNRTTRQLSLTEEGERYFRRVQQILQEMAAAETEIMESRNTPRGLLRIDAATP
                     VMLHFLMPLIKPFRERYPEITLSLVSSETFINLIERKVDVAIRAGTLTDSSLRARPLF
                     TSYRKVIASPDYIARFGKPESVEELKQHLCLGFSEPISLNTWPIACSDGQLHEIECGI
                     SSNSGETLKQLCLNGNGIACLSDYMIDKEIARGELVELLADKRLPVEMPFSAVYYSDR
                     AVSTRIRAFIDFLSEYIRTAPAGAVKEG"
     gene            complement(15062..15865)
                     /gene="dkgB"
                     /locus_tag="OPV72_002681"
     CDS             complement(15062..15865)
                     /gene="dkgB"
                     /locus_tag="OPV72_002681"
                     /EC_number="1.1.1.346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,5-didehydrogluconate reductase DkgB"
                     /protein_id="HCR9914934.1"
                     /translation="MTIPAFGLGTFRLKDDVVIASVKTALELGYRAVDTAQIYDNEAA
                     VGQAIAESGVPRNELYITTKIWIENLSKDKLIPSLKESLKKLRTDYVDLTLIHWPSPG
                     DAVSVEEFMQALLEAKKQGLTREIGISNFTIPLMEKAIAAVGADHIATNQIELSPYLQ
                     NRKVVDWAKAHGIHITSYMTLAYGKALKDEVIARIAVKHNATPVQVILAWAMGEGYSV
                     IPSSTRRENLASNLLAQDLHLDAEDKNAIAALDCNDRLVSPEGLAPAWD"
BASE COUNT         3919 a         4376 c         4210 g         3522 t
ORIGIN      
        1 taaaaagggt gtcatcaata atgactccct atgaatttag ttaaaattat ttatgaatta
       61 aaactcccta aacgtttcct ccagaaaaat aaatacattt aagggacata atgaaacaag
      121 acatgtggga attacggaaa atacagtcgc agggtataac ggataacgca cagtatcccg
      181 cagggacata catcgtattt actgccgccg ccccctacat tccgcttttt gagcaacatg
      241 ggaaagacga tatcgcgctc agtcttgttc gccacgaaga ggcgtggtgg attgttaatc
      301 actcggatga actgtgctgt gccgtcaatg agcaggtgat ggaacctcat caccgtatgc
      361 ggctgaatga tggagatacg attgaatggg gtctgtcatc ctggtgcctt gcccgcacca
      421 atgatgagtc ccgtcccgat gtttcgtttc ctcagttggt tcagtcatct gaatccgttg
      481 ctgagtacct ggatctggac tggtttaaac aacaacagct caatccgcag aacccgttcg
      541 atattattcc cgtccgggaa accgcgccct cttacaccgg ccatgaagcg gatagcacgc
      601 tacaccagct ttaccaggaa tatcagcagg ccttgcggcc ctccgggcag gaaaagcccc
      661 tccgtcctaa accgtttccc cgaaatgaag acgctgtcac ccaggatttg acgtcgttat
      721 acgataaaaa gggcgatacc gacacgttac aggatatggt ggcaggcgcg cccggtattg
      781 atgccattct ggatacgctg gacacgaccg gtgagggtga aatgcactgg ctggcgatgg
      841 aatcaatgcc cgatatccta caactgctct cgccggaaat gggggggaaa accgcacata
      901 gcgagatact gcccgatctg acccgccgcg agcatcgtat tattggcatc gatagccact
      961 accgaatcac tccgacacag aaaaatggaa ataccgccca tgaaaaaaac tgacacgctt
     1021 cctgctaccc tgtccgcgct gctacaggaa tactctattg cggaggggat tcagatggcg
     1081 gagcagcagg ttcgggaaaa tccggcgaag gcgctctgcc gccacagcct gtttcagttg
     1141 ctgtgtgtgg ccggagactg ggcgcgggcg ctacaccagc ttcagctctg tgccaggatg
     1201 gaggcaaatt atacccagga ggcccggctg taccgggagc tggtttgctg cgaaatgttc
     1261 cgccacaccg tttttcaggg tgaacaacga cccggttttc ttctgccgca gcccgtttgg
     1321 gtggagtcac tgctggcggc actcgcctgt catgacgata ccggtgaggt tgataaacac
     1381 cgtaataccg cactggaagc cataacagac acgggcgggc agtggaacgg cggcgcattt
     1441 gactgggcga gcgacagcga ttcccgcctt ggcccggtac ttgagctggt caccggcggc
     1501 gtgtatatct ggctaccgtt ttcgcaaata cgctcgctgg aatcgccgca accgacgcgc
     1561 ctgaccgatc tgctgtggaa acccgttaat atcaccctgg tgaatggcga tacgcacggt
     1621 gcctggctct ttacccgtta cagcggttcg gaaagtgcat ctgacgccct gcgtctgtgc
     1681 cgggaaaccg cctggcagga cggccccggc gaaaccaccg tgcgagcgct ggggcagaaa
     1741 gtgtggctga ccagccacgg cgatatcagc ctgctggaca tgacccattg tacctttcat
     1801 gctcaggaaa acgatggcgc atgagcacgt ctcgttttac acccgctaac cacctgctgc
     1861 ctacgctgtt tgatcggctg tgtgacaatg ctccgtatca gaaaattgac cgggatatca
     1921 gcgtcacgcc ggtacaactg aaggagatca ttcgtcggga tctctccttt ttgctcaata
     1981 ccattagcca cgagggtgac atcgacgccc ggcgctatcc gcaggcggcg gcgtcagtgc
     2041 tcaactatgg cctgccgccg ctggcgggca gctttatgta tgagcacaag tgggacgata
     2101 tcagcgaggc gatccggcgc gccattatcc gtttcgaacc ccggctgaac gccgccacac
     2161 tcagggtcac gcccttgctc gatgaagccc ggcagggtag ctataacacg ctacagtttg
     2221 aaattcgcgg acaaattctg acgcagccgt atcccacgga gtttctggta cgcagcgcgc
     2281 tggatatgga gctgagccgc attacgttct tttaatacag ggcattattc atggatccac
     2341 ggctactgga gtattacaac cgcgaactga gttacctgcg ggagaccggt gctgagttcg
     2401 ccaccctcca tcccaaaatt gccgcccgac tggggatgca gggaaccgat attgccgacc
     2461 cgtatgtgga acgcatgatc gaggcgttca gctttctgag cgcccgcact cagctaaaaa
     2521 ttgacgccga atttccccgc ttcacacagc ggttactgga agtcgtcaac cccaattacg
     2581 tcacccccac gccatcgatg gcagtggtaa agctgtatcc cgatacgcag gaaggcgacc
     2641 tggcgaaagg ggtcaccgtg ccgcgcgata ccgcgttcgt ttcccccatc ccggaaggcg
     2701 aaaataccgc ctgccagttt cgcagcagcc aggacgtcac gctgtggccg ctgtccatcg
     2761 aggaggtacg cctgaccgcc gcgccgccgg atatgcccgc cctgcaccgc tatctgccgc
     2821 ctaatattca tgtcgccggg gcattgcgca tcaccctgcg aaccttcggg gaactggctt
     2881 tcagcgagct ggccggtccg gcacggctgc ccttttacct ctgcggcgaa gaacgcattg
     2941 cgtcacacct gtttgagctg ctacatacca gcgccgtcgc cacactggcc ggagaacccg
     3001 gtcactttga cggcgaactg aatgtgaatc ttcaacaccc ggtggcgcac gaagggctgg
     3061 agccagggca ggggctgctg ccgctcgcct ggaacgtgtt tcatgggcat aatctgctgc
     3121 atgaattttt cgcctgtccg gaacggtttt acttcttcac cccgaccgga ttgtctgccg
     3181 gtctacaaaa ggtgcagggc aatgtggcgg aaattgttat actgcttaac cgcctgccgc
     3241 cggactggct gattcatcag acggacgccg cacagttcag cctgttctgt acgccggtga
     3301 tcaacctgtt tccccgcacc accacccgga ttgaagtcac tcacagcgtg acggaacagc
     3361 atctggtggt ggatcgtacc cgtccgctgg attacgaggt gttttctgtc caggaagtcg
     3421 aaggcctgga agcggaaacc acacggaaga tgatttttcg tccgctgtat cacacccgta
     3481 ataatgacga aggcaaccac gggcgttatt tttcactgcg tcgtgagccg cgccgatcgt
     3541 cagaaagcgc ccgccgctat ggcacccgaa ccccctatac cggctcggaa gtcttcctct
     3601 cgctggttga tcagcatgaa gcgccctacc cggaaaatct gcgccatatc accgtcacgg
     3661 caatggtgac taaccgcgat ctgccctgcc ttattccacg taatggccgg gatgatctga
     3721 ccgtagatgc ggcgattccg gtggcgggcg tgggtcttat cagaccgccg cgcccgccgc
     3781 agccgccgct ggctgaacgc gaaatggcct ggcggctgat ccggcagttg tcgtttaatt
     3841 atctgccgct ggccgatctg gatcaccgca ccggcggcca ggcgctgcgc gatctgctga
     3901 acctgtttat cccggctcac gacagcccgc agtcgcgcca ggtgcgcagc ctgattggct
     3961 gcaaaaccac cccggtgacc cgccgcctac ccggctccgg cctgttggtc tatggccggg
     4021 gcgtcagttg cgaactgacc gtggacgaag aaggattttc cggtatcagt ccttacctgt
     4081 tcggtctggt gctggaacac tatattgccc gccatgtttc cattaatacc ttctcgcaga
     4141 tgacactgca ctcgatgcaa cgcgggcatg tcatgacctg gccggtcaga accgggcaac
     4201 gggggagcgt atgaccggcg ctctcgacca ggcgcagaaa gccccctggc gttacggatt
     4261 cctgaacctg atgcgacgcg tggatgccca gctctgtgat actccggcag gcagtatctg
     4321 gcagcctcgg atggaaaaat tccgtctggg acagacgccg acgatgacct ttgcaccacg
     4381 ggaaatcgcc caggtcagct ggcaggatgg acgcctgcac ctgagcctgt acagcctcgg
     4441 actatggggg ccaaacggcc cgttgccgct gcactatacc gagctggcgc taaatcgctc
     4501 agagagtcgt cacgatccga cgctggttca tttttccaat atttttcact accgctggct
     4561 gacgcagttc tggcaggcat ggcgcagcgg ccagtccgct ggtggcgggc tggacaaacc
     4621 ggaacacgac cgttttgcgt tttatatcgc cagtatcagc gggcaggatc tacgggaaag
     4681 cgccgaaagc ccgctgtcag atcatgttcg cctggcggcc tccgcccatc tggtacgcga
     4741 gtcgcgcaat cctgacgggc tggccgccac gctggcgcac tatttcagcg taccttttgc
     4801 ggtgaaagag tttgccctgc actggataac ggtggcgaac gatgaaatca cccgtctggg
     4861 cacgcccgcg cagtcttcgg tgctgggcaa cggggcgctt atcggccagg ccgtaccgga
     4921 tatgcagtac aaattccggc taattatcgg cccgctcacg ctggaggatt acctgcgttt
     4981 tctgcccggc ggcaacaatc tgcccgtgct gacagaactg gtgcgtacgt tcatcggttt
     5041 tgaatattgc tgggaaattg agctgcagtt gaagccccat gccgcaccgc ctgcggtgat
     5101 cggcggcgcg cagcggcttg gctggacggc ctgggcaggt aaagccatgc atgaccgtcc
     5161 ggtgaccggc atgatttttg aacctgaaca cggcttaacc cactgagagt aatgatatgg
     5221 acatgtccct gactaaaccg gtaagcgcgg aacaaccctg cggccccgat ccggagtacg
     5281 atccggaata cctgctgctg ttcagccgcg ccgcccccca ggcggaggcg caatatggtg
     5341 attttgtcag tacgccggaa gccgtgaact ggccggaaat tgagcgtgat gcgcgccgtc
     5401 tgctcacgcg cagtaaggat atccgggtgt tgatcctgct gctgcgcagt cgcatccagc
     5461 aggctggcgc acagggactg gcggaaatgc tcacacaact ggcagaactg agcgtaatct
     5521 ggtctgatgc actccatcca cagctgctta ccggcgaagg cgcatccgca gaatctattg
     5581 aagatgcggc gctggcgcgc agtaatgccc tggcggcgcg ctggatcacg aaggcgtgat
     5641 ggcagacatt cgcggtatca cgctgtcaaa cagtgccgcc ctgcacctgc aggtacggga
     5701 cgtggagcgc gcgttatccg cccctcgccc ggctgatgcg ctggcccccg aatccgtccg
     5761 ccagcaactg gcagacctcg aagcccgtgg ggcattaccg ctagcggcgt ttcgcgaagc
     5821 gcaggaaagc gcagaacgcc tgcaagtgtg ggcgcgtgag acattaggcg atctggctcc
     5881 agatttttca cgcctgcggc agttgttagc gctgctgcct gacgtggtac agacaaccac
     5941 gccggaaatc cctccgtcgc cagcgccagc gccagctccc gcaggcacgg ttatggataa
     6001 tgccattcct gcacgggcag aggatgtgcc gcctgtcaac gcgccacccg gtatatctat
     6061 cccacacaat gctgaaccgg ggccaattcg cgatcgtaat gatgcgctgg aacgcctgcg
     6121 gtgcattcgt cgctggtttg agagcagtga acccagcagc ccgaccatcc cactattacg
     6181 tcaggctgaa agactggtgg gaaaacggtt ctcggaggtg atcaatgaga tcccggtgga
     6241 gttgctggag aagtgggatg ccctggagtg atgatgcgca tgtctggcgg ttctccgtga
     6301 ttatctgagt gacatcaaca ttactcggtc tgcttctgcg ctgaacatgt cccgatcccg
     6361 gttaagcacc gccatgaggc cgcgccttaa atgtcagtgg gacaaaataa ccatgacagt
     6421 gaaagaagtg gcggtaatat cctgttcgtc atccaggcgt aggcccattt gcgccagatt
     6481 ccacgataga cggtggaact tcttgaagac gaaaaaaaac cgtatccctt ttacagtgat
     6541 acggtttttt tacttcacag gatgtataaa aacaccctga gatttgtatc tggcggaacg
     6601 gacgggactc gaacccgcgc ccccctgcgt gacaggcagg tattctaacc aactgaacta
     6661 ccgctccgtg atgttcccgc tgggaacgag gcgaatatta cggtttgcgg tgtcgcccgt
     6721 caacgctttt tctcaccttt tgaatcagtt gctgcaaaaa tcgcccgaag gatgattttt
     6781 atagcctaaa aaggaataaa ttatgcccgc caaaggcaac ttccgccctt tttctgcacc
     6841 agatcaagcc gcgattcatg cgcagccagc tcttcctcag aggcaaaaac gacccgtaac
     6901 cggctggcct ggcgaacgat tcgctgaatg gtcgcttcac cttgctgccg ttgcgtctct
     6961 ccttccatcg caaacgtcat ggacgtttgt ccgcccgtca tcgccagata cacttcggca
     7021 aggatctggg catcgagcaa tgcgccgtgc aaagtacgtt tgctattatc tatctcataa
     7081 cgcgaacaca gcgcatcaag gctgttacgc ttgccgggga acattttccg cgccaacgcc
     7141 aggctatcgg taactttgca gaaagtattg gttttaggaa tatcgcgttt aagcagacca
     7201 aactcataat ccataaagcc gatatcgaac gatgcgttat ggatgaccag ctccgcgccg
     7261 cggatataat cgagaaactc atcgaccaca tcagcaaaaa ccggcttatc cagcagaaac
     7321 tcatcggcaa taccgtgtac gccaaacgct tccggatcca ccagccgatc cggcttcagg
     7381 taaacatgaa aattgttgcc ggtcagacga cggtttatca cctcaaccgc accgatctca
     7441 ataatcttgt gaccttcata gtgcgcgcct atctggttca taccggtggt ttcggtatcg
     7501 aggacaatct gtcgtgtaat tgcagtgctc atatcggtca tttatgtcag acttgcgttt
     7561 tgttatcgat ttcaattaca ggaagtctac cagagatgct taaacaggta gaaattttca
     7621 ccgatggctc ttgcctgggg aatccagggc ctggtggtta tggcgctatc ttacgctatc
     7681 gcggtcatga aaaaacgttt agtgaaggtt acacgctgac caccaataac cgtatggaac
     7741 tgatggcggc gatcgtcgcg cttgaagcgt taaaagaaca ttgcgaagtg acattgagca
     7801 ccgacagcca atatgtgcgg caaggaatta cccaatggat tcataactgg aagaaacgcg
     7861 gctggaaaac agcggaaaag aaacctgtaa aaaatgtcga tctctggaaa cgtctcgatg
     7921 ctgcgttagg ccagcatcag atcaaatggg tatgggtcaa aggccatgca ggccatcccg
     7981 aaaacgagcg ttgtgatgaa ctggcgcgcg ccgcggcaat gaatcccacg caggaagata
     8041 gtggctacca ggcagaagct tagccatccg gtttgcgata ttgccgggtg gcgccaacgg
     8101 tctggcggat aggggtttta cttttattat gtcgcagcgg attaagcgta agcggaatgg
     8161 tccgcttacg ggccacaata agctgtaaac agcccagcgc cgggatatgc gtatttaaaa
     8221 gccgccctcc ctgctttttc cagggtaaga catgaaaacg gctataatgt agcacttcga
     8281 aattgagtaa agacagccag tccagttgcc gcataagggt aaacatccga ctattatagg
     8341 gcggtgtttt acgtaaaacg agtaccagtt tacgtaaccc catcaaactc agcgggttaa
     8401 atccactgat gaccagccaa ccgtcatcaa tcaatacgcg gtcggcttcc cgcaataaac
     8461 ggtgcgggtc ggtacaccac ggcaaagtat gcgccagcag acaaacatcg acggatttat
     8521 ccgcaaaagg aagatgtagc ggatcggcca gaacctgcat cggcgacccc tgcgatgaaa
     8581 cattcacttg atgggagacc gcgcacgctt cggaattgat ttctgcgctt aaattaccga
     8641 ttttaagcaa atggaaacca tacatttttg caaaccacgg atttagctgc tgttccagcg
     8701 cctcacggta gtaattgccc cagggcaact caccccaaca tccgggcgca acgacagttt
     8761 gagagagcct tgccggtttc atcgcaacct tccgctaatt atttgagagg taatatatga
     8821 atcttaacag tattcccgcg tttcaggaca attacatctg ggtgctgacc aatgatgaag
     8881 gccgctgtgt gattgttgat cccggcgaag cggcccccgt cttaaaggcc attgctgcac
     8941 ataagtggat gccggaggcg atttttctga cgcatcacca ttacgaccat gttggcggag
     9001 tcaaagagct gttgcaacac ttcccgcaaa tgacggttta tggaccggcg gaaacgcaag
     9061 acaagggagc aacccatctt gttggcgatg gcgatactat tcgcgtttta ggcgagaaat
     9121 ttactctttt tgccacgccg ggccacacgt taggacacgt ctgttacttt agccatcctt
     9181 acttgttctg cggcgacacg ctgttctctg gcggctgtgg tagattgttt gaaggcacgc
     9241 catcacagat gtatcagtca cttatgaaaa ttaactctct gcctgacgac acactcattt
     9301 gcagcgctca cgaatacact ttagctaaca ttaagttcgc attgagcata cttccgcacg
     9361 attcgttcat aaatgaatat tatcgtaaag ttaaagagtt acgtgtaaaa aaacaaatga
     9421 cactacccgt tattcttaaa aatgagcgta agattaatct ttttttaaga actgaagata
     9481 ttgatttaat taatgaaata aacaaagaaa caatattgca acaaccagaa gcgcgttttg
     9541 catggttaag gtcaaagaaa gacacgttct gataattctt acttgtcatt cgctaacttc
     9601 gccgttatga tcggtcgtct tttaagcaac tattgacaca cacatgaagg caaaagcgat
     9661 attactcgcc tctgtcctgc ttgtggggtg ccagacatct cagaacactg gcaacgtcca
     9721 acagcacgca cagagccttt ctgcagctgg tcaaggggaa gcaggaaagt ttacgagtca
     9781 ggcacgatgg atggacgacg gaacgtctat cgcgccagat caggacttgt gggctttcat
     9841 tggcgacgag ctaaagatgg gaattccgga aaacagccgg attcgcgaac agaaacagaa
     9901 gtatttacgc aataagagct atctccacga tgtaacttta cgggcagagc cgtatatgta
     9961 ctggatagcg gggcaggtta agaaacgtaa catgcctatg gagctggtac tactacccat
    10021 agtggagagc gcttttgatc ctcacgcaac gtctggcgcc aatgccgcag gcatctggca
    10081 gatcataccg agcacagggc gcaattatgg tttaaagcag acccgtaatt atgacgcgcg
    10141 tcgcgatgtt gtagcctcta cgaccgccgc gttagacatg atgcagcgtc tgaacaaaat
    10201 gtttgacggc gactggctgt taactgttgc agcgtataac agcggcgaag gccgtgttat
    10261 gcgggcaatt aaagcaaaca aagcgcgtgg aaaaccgacg gatttctggt cgctttcttt
    10321 gcccagagaa acgaaactct acgtacctaa gatgctggca ttgagtgaaa ttctcaaaaa
    10381 cagcaaacgc tacggcgtac gtctgccaac aacagatgaa agccgagcgc tggcacgagt
    10441 tcgtttaaac agtccagttg aaatggccca ggttgcggat atggcgggca tgtctatcag
    10501 caagctgaag acgtttaatg ccggtgtaaa agggtctacc ttaggcgtaa gcggtccgca
    10561 atatgttatg gtgcccaaaa agcatgccga gcagttgcgt gagtcgctgg cttccggtga
    10621 gattgacgcc gttcagtccc aactgatcgc cgacaatacg ccgttgaata gccgtagcta
    10681 taaggtgcgc tctggcgata cgctttccgg tattgcttcg cggcttggcg taagcacgaa
    10741 ggacttgcag cagtggaaca acctgcgtgg ttcccgcctg aaaatcgggc aaagcctgac
    10801 cgtgggcgct ggcagcagcg cgcaacgact ggcaaacaat agcgatagca ttacctatcg
    10861 tgtccgtaaa ggcgattcgc tttccagtat cgccagacgt cacggggtga atatcaaaga
    10921 tgtgatgcgc tggaaccatg atacggataa tctacaaccg ggcgatcagc ttacgttgtt
    10981 tgtgaaggac aatagcacgc cagactcctg atattgtccg acgaaaaagc caaaaggcgc
    11041 cgcttccccc ggcgcctttt aaattgttat accgctttat gcgcttccag catgatagta
    11101 tcgctgctaa acgagccgtc atcctgcaac tcaaaataac gcttcacctc taccggggcg
    11161 ctcgcctgat ataatcgaat cgcctcaacc aacggcgctg gcgtacgcat ccgcgttacc
    11221 catgagcgaa actccagcga taaacgatcg gttatcacgg tattcgttac cagcatcgcg
    11281 ttattgacca tcgccagcca ttcaccactg gaatagttac ggacatgcga cgtgtcgcgt
    11341 aacgcctcca ccgtttgcag ccagatatcg cgtacaggat gtccaggcga catgacatcc
    11401 atgataatca gcacgccgcc gggttttaat acacgataaa cctcacgcaa tgcctgacca
    11461 acgtcgtgcc agtgatgcgc ggaatagcgg ctaatcacca cctcaaacga tgcatcttca
    11521 aagggcagtt tttcggcata gccttgccgg agagtaatat tacttaaatg tctttcttcc
    11581 gccgctccag cgacaacctc aagcatgctg gcggataaat cgtatgccac gaccgaattg
    11641 acatgttgcg cagcgacaaa actcgcgtgt ccagccccac atcccatatc cagtacgctc
    11701 gcgtgggaaa aatcagacaa cctttgcgcc agccgcgcta agtcacgacc cgctgcgtga
    11761 acggcgctat gtaaataggc gttcgcctgt gaaccaaact gcttttcaac attgtcatgg
    11821 tgggaatgcg ttgtcatggt agtgcccttc tgttatgaga aaaatagagg gcagcacccg
    11881 cagaggcctg ccccacggca gacctgactc acctttattg ctcaggtttg ccgggactga
    11941 attcaacgag tagcggattg tgatcggaag cgcgcgtcac cagtacggag gcttcattca
    12001 cgtttaaacc acgataaaaa acaaaatcca gcggtcgtcc aaacgcacga cggcgttgat
    12061 cgtcagtgaa acgcacctgg cgcagcgaca tctcacgtgc aaagcggtac aacgcattca
    12121 tacgtgggcg gctccaggca ttaaaatcac ccgccataat gacagggccg ctatggtgcg
    12181 caatctggtc gccgatcgga agtaactgct tactgtatac gtccacgccc agactaaaat
    12241 ttaccgcatg aacatttact accattaata aacgggtatc cggcaaggga tataccgtca
    12301 ccagggctga tttcgccaaa cgtaaaattg gttctctttc ccgtaaaggg cagcagtaaa
    12361 caggatgggc ggcagaaagc gtcataacgc cagacgggtg ctgaggtaat acaaaagcgg
    12421 gaacctgatc ggcggcaaga tagttagcgg tggcaaactg taccagttca ggcgtcgtct
    12481 gggcctcctg caacaggacc agatgcgcat ctttgccgta gttcttcagc accgataacc
    12541 attcggctcg ctgctgcttg aatatattcc acacgaggat acggatccgc tcttcactgc
    12601 ttagcggttc cccggcgggc aatgcctggc caatgctcgc aaacgaccct agcggcaaaa
    12661 tccgctcggc gggctgtccg gcaacatagc gcatcgcata ggtgtttttt cgcacttttg
    12721 actttcaaac ctctgtaacg tcaaccagtc ctcaaccgga ctggttcttc tgttataggg
    12781 attttagcac tcactttcaa cgaacaattg cagtttgttt tgtaagtagg cgcttacatc
    12841 aataatttac tccagagcaa tgcgcacagg tttatcaaga cgtccgctga cgcccatcag
    12901 cagaaaagcc accagaacaa tgagggcgcc aatccacggc gtctgcgcca aaccgtaatg
    12961 cgccaccgtt tgtccgccaa tcacggaacc cagcgcaata ccaatgttaa acgccgcaat
    13021 gttcagacct gacgccacat caacggcatt aggcgtgaat tgttccgctt tctgtaccac
    13081 gtagacctgc aaccccggta cgttaccgaa ggcaaagatc cccatcacca gaatggtagc
    13141 cagcgcggca tactgcgtgg aggccgtcac ctggaagacc atcagcagaa caaacagcgc
    13201 ggcgaaaatg aatttcagag ccggcacggc accatgctta tccgccagtt taccgcccca
    13261 gatattgccg atagccactg atacgccata acccagtagg atccagctta ctgctgccgg
    13321 agagaatccc gccagatcct gcatcatcgg cgccaggaag gtgaatgccg tgaatacccc
    13381 gccgtagccc agcgccgtaa cggcgtaaat cagcagcaga cgaggatgag tcagtacttt
    13441 cacctggtca cgaatgctgg cggccgcccg accaggaata ttggcaggga tcagcagttg
    13501 actgctcatc agcgcaatca cgcctaacag tgataccgca aggaaggtct cacgccagcc
    13561 aaaatgctga ccgataaatg tccccagcgg aacacctgtt accagcgcta ctgttaaacc
    13621 accaaacata atagcgatag cagaagccgc tttctctttc ggcaccagac ttgtcgcgat
    13681 ggtagagcca atcgagaaga acacgccgtg cgccaggccc gtcagcagac gggcggcgat
    13741 taatgtcata tagcccggag cctgccacgc cagcaaattc cccgccgtaa acaagaccat
    13801 cagcgcgacc agtaactgtt tacgcggcag gcgtccggtc agagcggtta gcaccggcgc
    13861 gccaatagcc acacccagtg catagattaa aaccagcatt ccggcagaag gtaacgagac
    13921 agccagttgt tgtgcaatgg tcggcaccag gccgacaatc acgaactcag tcgtgccaat
    13981 agcgaaggca cttattgtca gtgcaaataa agcgagaggc atacataact ccataacagc
    14041 agtaatcaga tgacacgcag tatgccagga tgttttaatg acaaaaatag ccaaaatata
    14101 aatttaattt tgctgcagga gcagaaatga aagccacctc cgaagaactt gcaatttttg
    14161 tcgctgtcgt ggaaagcggc agcttcagcc gggcggcaga gcagctcgga caggccaatt
    14221 ccgctgtcag tcgggcagtt aaaaagctgg agatgaagct cggcgtcagt ctgcttaatc
    14281 gaacgacccg acagttgagc ctgactgaag aaggagagcg atacttcagg cgtgtgcagc
    14341 agatactgca agaaatggct gccgcagaaa cggaaatcat ggagtcgcgt aataccccac
    14401 gcggcttact gcgtatcgat gcggcaacgc cggtaatgct gcatttcctg atgccgctga
    14461 ttaaaccttt tcgtgaacgg tatccggaaa taaccttgtc tcttgtctcc tcagaaacgt
    14521 tcatcaatct tattgaacga aaagtggatg ttgcgatacg cgcaggcacg ttgacagatt
    14581 caagtctgcg cgcacgtccg ttatttacca gctatcgtaa ggttatcgcc tcaccggatt
    14641 atattgcccg ttttggcaag cctgagagcg ttgaagagtt aaaacagcat ctgtgcctgg
    14701 ggttttctga acctatctcg ctcaatacct ggccgatagc ctgtagtgac ggacagctcc
    14761 atgagatcga atgtgggatt tcgtccaaca gcggggaaac gttaaaacaa ctttgcctga
    14821 acggtaacgg cattgcatgt ctttcagatt atatgattga taaagagatc gcgcggggag
    14881 aactggtgga actgctggcc gataaacgtc tgccggtaga aatgcctttc agcgccgttt
    14941 actacagcga tcgcgccgtc agcacacgta ttcgggcatt tatcgacttt ttgagcgaat
    15001 atataagaac agcccccgca ggagctgtga aagaggggta aaggtacaaa ggatcgggta
    15061 attaatccca ggcaggagcc agtccttccg ggctaaccag acgatcgttg cagtccagcg
    15121 ccgcgatcgc atttttatct tcggcatcca gatgcagatc ctgcgccagc aggttgcttg
    15181 ccaggttttc acgcctggtg gatgaaggga tcaccgagta accttcgccc attgcccatg
    15241 ccagaataac ctgcaccggg gtcgcattat gtttaaccgc aatgcgcgca atcacttcat
    15301 ctttcagcgc tttaccgtat gccagcgtca tgtaagaggt gatatggata ccgtgcgctt
    15361 tcgcccagtc aaccacctta cgattctgca gatacggaga tagctcaatc tggttggtgg
    15421 cgatatggtc tgcgcccacc gcggcaatag ccttttccat caacggaata gtgaagtttg
    15481 agatgccaat ttcgcgagtc agcccttgtt ttttagcttc cagcaatgcc tgcataaatt
    15541 cttcgacaga cacggcatca cccggagatg gccagtggat cagcgtcaga tcgacataat
    15601 cggtacgcag ttttttcagg ctctctttca ggcttgggat tagcttgtct ttgctaaggt
    15661 tttcaatcca gatcttggtg gtgatgtaca gctcattacg cggtacgccg ctctcagcaa
    15721 tcgcctgtcc aacagccgct tcattatcat agatttgcgc agtgtcgaca gcacggtagc
    15781 ccagttcaag cgccgttttc acagaagcga taaccacgtc gtctttcagg cgaaaagtac
    15841 ctaaaccgaa tgcagggata gtcatagaat tcctcttttt aatcactatg ttcgttaact
    15901 gaggggatta tgaccttcag cgctttgtag aaaaagagcg agaaatgcag aggatttttg
    15961 cgaattgagc aataattaaa tcgcaggcaa agaaaaagcc ctgagctaat gctcagggct
    16021 cttaata
//
LOCUS       DAJVBX010000101        16014 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.101, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000101 DAJVBX010000000
VERSION     DAJVBX010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 16014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16014
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.101"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(25..3549)
                     /gene="nifJ"
                     /locus_tag="OPV72_002682"
     CDS             complement(25..3549)
                     /gene="nifJ"
                     /locus_tag="OPV72_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HCR9914935.1"
                     /translation="MQTIDGNGAVASVAFRTSEVIAIYPITPSSTMAEQADAWAGNGL
                     KNVWGDTPRVVEMQSEGGAIAAVHGALQTGSLSTSFTSSQGLLLMIPTLYKLAGQLTP
                     FVLHVAARTVATHALSIFGDHSDVMAVRQTGCAMLCAASVQEAQDFALIAHRATLKSR
                     VPFIHFFDGFRTSHEINKIIPLTDETILNLMPQAEIDAHRARALNPEHPVIRGTSANP
                     DTYFQSREATNPWYNAVYDHVEEAMKAFGDATGRQYQPFEYYGHPQAERVIIMMGSAL
                     GTCEEVVDELLIRGEKVGVLKVRLFRPFSAKHLLQALPETVRAIAVLDRTKEPGAQAE
                     PLYLDVMTALAEAFNNGERETLPRTIGGRYGLSSKEFGPACVLAVFNELSRAKPKPRF
                     TVGIYDDVTNLSLPLPENTLPGSAKLEALFYGLGSDGSVSATKNNIKIIGNSTPWYAQ
                     GYFVYDSKKAGGLTVSHLRVSEKPIRSAYLIAQADFVGCHQLQFIDKYQMAERLKPGG
                     IFLLNTPYSADEVWSRLPQEVQAVLNQKKARFYVVNAAKIARECGLGARINTVMQMAF
                     FHLTHILPGDSALVELQGAIAKSYSSKGQDLVERNWQALALAQESLAEVPLQAVNPHS
                     AHRPPVVSDAAPDFVKTVTAAMLAGLGDALPVSALPPDGTWPMGTTRWEKRNIAEEIP
                     VWKEELCTQCNHCVAACPHSAIRAKVVSPQAMENAPASLHSLDVKSRDMRGQKYVLQV
                     APEDCTGCNLCVEVCPAKDRQNPQIKAINMMSRLEHVEEEKVNYDFFLDLPEIDRSKL
                     ERIDIRTSQLITPLFEYSGACSGCGETPYIKLLTQLYGDRMLIANATGCSSIYGGNLP
                     STPYTTDANGRGPAWTNSLFEDNAEFGLGFRLSVDQHRARVMRLLAQFADRIPAELND
                     ALHAEATPDVRREQVAALRQHLKSVAGAEELLKDADALVEKSIWLIGGDGWAYDIGFG
                     GLDHVLSLTENVNILVLDTQCYSNTGGQASKATPLGAVTKFGEHGKRKARKDLGVSMM
                     MYGHVYVAQISLGAQLNQTVKAIQEAEAWPGPSLIIAYSPCEEHGYDLALSHDQMRQL
                     TATGFWPLYRFDPRRADEGKPPLALDSRPPSDALAETLLNEQRFRRLNAQQPEVAEQL
                     WRDAALDLQKRYDFLALLAGKAEKPSAD"
     gene            complement(3610..3921)
                     /locus_tag="OPV72_002683"
     CDS             complement(3610..3921)
                     /locus_tag="OPV72_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="reverse transcriptase"
                     /protein_id="HCR9914936.1"
                     /translation="MAKHAPQLPAEQVRYCKPTIITRHIPPKTLRAFLSPLFIHPNDT
                     ALNNRQQKLTRREAKRAFMRFINIYWQFFTSFRQEIAILLPPGTQKRKWGLKGFAKIK
                     G"
     gene            3825..4091
                     /locus_tag="OPV72_002684"
     CDS             3825..4091
                     /locus_tag="OPV72_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015964583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF333 domain-containing protein"
                     /protein_id="HCR9914937.1"
                     /translation="MRAAFWVGCAALLLSACSSEPVQQATAAHVSPGMKAAMSSAGEA
                     NCAMIGGSLSAARQLDGSVIGMCALPNGKRCSEQSLAAGSCGSY"
     gene            complement(4135..4545)
                     /gene="hslJ"
                     /locus_tag="OPV72_002685"
     CDS             complement(4135..4545)
                     /gene="hslJ"
                     /locus_tag="OPV72_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock protein HslJ"
                     /protein_id="HCR9914938.1"
                     /translation="MKKIVTLVALSIIMTGCVSSGKVSVKREQLEHHRFVLESVNGKT
                     VTGPELSFGEDMTVSGKMCNQFTGEGKLSDGELKVKNLAMTRMMCADPQLNALDGTLS
                     ELFSKGAQVDLTANQLTLATAETTLMYKLADLAH"
     gene            complement(4656..5645)
                     /gene="ldhA"
                     /locus_tag="OPV72_002686"
     CDS             complement(4656..5645)
                     /gene="ldhA"
                     /locus_tag="OPV72_002686"
                     /EC_number="1.1.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase"
                     /protein_id="HCR9914939.1"
                     /translation="MKLAVYSTKQYDKKYLQQVNEAFGFELEFFDFLLTEKTAKTANG
                     CEAVCIFVNDDGSRPVLEELKKHGVKYIALRCAGFNNVDLDAAKELGLQVVRVPAYSP
                     EAVAEHAIGMMMTLNRRIHRAYQRTRDANFSLEGLTGFTMHGKTAGVIGTGKIGVAAL
                     RILKGFGMRLLAFDPYPSTAALDLGVEYVDLQTLFAESDVISLHCPLTPENYHLLNHA
                     AFDQMKNGVMIINTSRGALIDSQAAIEALKNQKIGSLGMDVYENERDLFFEDKSNDVI
                     QDDVFRRLSACHNVLFTGHQAFLTAEALISISETTLQNLSQLEKGEACPNALF"
     gene            5912..8548
                     /locus_tag="OPV72_002687"
     CDS             5912..8548
                     /locus_tag="OPV72_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbH family protein"
                     /protein_id="HCR9914940.1"
                     /translation="MKGKYKAALALLLLLILVPLTLLMTLGLWVPTLAGIWLPVGTRI
                     ALEQSPRLTRHGLVIPDLRYLVNDCSLAHITQAELTHPSRWLLNIKSLKLDAACLAKL
                     PASEASPAAPRTLAQWQSMLPNTWINIDNVILAPWPEWQGKLAISMTPVIQQIRYQGE
                     KVKFQGQLRGQALTVSQLEIAALANQPPVSLAGEFMLPLVPDGLPVSGHAAATLRLPQ
                     EPSLVDAELEWRDNAGQLIVMARGNPDPILDLPWAVTRQRLTVSDGRWNWPYQGFPLS
                     GRLAFNIDNWQAGPDNARVSGRLNILTQGDAGKANAVLTIGPGKLSMDSSEMPLQLTG
                     EAKQKDLIFYAVLPAMFRGSLADPQLTFAPGALLRSRGRVIDALDIDEIRWPLAGVKV
                     TPRGVDGRLQAILRAHENEMGDFVLHLDGLANDFLPDAGRWRWRYWGQGSFTPMRARW
                     DIAGQGEWHDNTIRLTSLSTGFDQLHYGAMTVTSPRLALDKPIVWVRDATTPSLQGAL
                     SLEAGKTVFTSGSVLPPSTLNFSVEGREPTLFQFKGDLRAGAIGPVRLNGRWDGERLR
                     GQAWWPKQSLIVFQPLLPPDWKMTLREGSLYAQVAFSAAQGQGFEAGGHGVLKGGSAW
                     MPDNKINGVDFILPFRFHNGAWQLGTRGPVSLRIAGIVNQVTAKNITADLQGGYPWSE
                     SNPLLLSDVSVDVLGGQIIMKQLRMPQHDPALLRVQNISSSELISAINPKQFAMSGPV
                     SGALPLWLNNEKWIIKDGWLTNPGPMTLRIDKDTADAVVKDNVTAGSAINWLRYMEIT
                     HSWTKINVDNLGVLTMQAAITGKSRVDGKTAIVNLNYTHEENVFTLWRSLRFGDNLQA
                     WLEQNTALPQPPCRKDKDCEDK"
     gene            8548..8739
                     /locus_tag="OPV72_002688"
     CDS             8548..8739
                     /locus_tag="OPV72_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnbE family lipoprotein"
                     /protein_id="HCR9914941.1"
                     /translation="MKMSIAMLSALASFIVVGCTPRIEVAAPEQPITINMNVKIEHEI
                     HIKVDKDVEELLKSRSDLF"
     gene            8747..9070
                     /locus_tag="OPV72_002689"
     CDS             8747..9070
                     /locus_tag="OPV72_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbL family protein"
                     /protein_id="HCR9914942.1"
                     /translation="MKKYLILWVLTLSLLTPSVWALTLDEARTQGRVGETLNGYLVAL
                     KNDAETQKLVLDINHARRASYQQLADSNHLPVDEVAKMAGQKLVKRARPGEYVQGING
                     KWMRK"
     gene            9213..9662
                     /locus_tag="OPV72_002690"
     CDS             9213..9662
                     /locus_tag="OPV72_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GFA family protein"
                     /protein_id="HCR9914943.1"
                     /translation="MTSEKLSAACHCGSVVFTVQLSDGFHTARRCNCSFCRMRGAVAV
                     SAPLSGIKVLKGQDKLTEYRFNTGKAVHFFCSVCGIYTFHQRRSNPDQYGVNVACIEN
                     VSPFDFACVEVNDGVTHPSDGGSSGVVGYLRYEPKKSPPVETGGKNI"
     gene            complement(9659..10264)
                     /gene="azoR"
                     /locus_tag="OPV72_002691"
     CDS             complement(9659..10264)
                     /gene="azoR"
                     /locus_tag="OPV72_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HCR9914944.1"
                     /translation="MSKVLVLKSSILAGYSQSGQLTDYFIEQWREKHVADEITVRDLA
                     ANPVPVLDGELVGAMRPGDAPLTPRQQDALALSDELIAELKAHDVIVIAAPMYNFNIP
                     TQLKNYFDLIARAGITFRYTEKGPEGLVTGKRAVVLSSRGGIHKDTPTDLIAPYLKVF
                     LGFIGITDVNFVFAEGIAYGPEVAAKAQADAKAAIDSVVAA"
     gene            10465..14367
                     /gene="hrpA"
                     /locus_tag="OPV72_002692"
     CDS             10465..14367
                     /gene="hrpA"
                     /locus_tag="OPV72_002692"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460600.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase HrpA"
                     /protein_id="HCR9914945.1"
                     /translation="MTEQSTLTLQVLQQRLDALMLRDKQRFSRRLHGVKKVKNPDAQQ
                     AIFQTMAKEIEQAATQVALREAARPSITYPQNLPVSQKKQDILEAVRDHQVVIVAGET
                     GSGKTTQLPKICMELGRGIKGLIGHTQPRRLAARTVANRIAEELQTEPGGCIGYKVRF
                     SDHVSSNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLKELLP
                     RRPDLKVIITSATIDPERFSRHFNNAPIIEVSGRTYPVEVRYRPIVEEADDTERDQLQ
                     AIFDAVDELGRESPGDILIFMSGEREIRDTADALNKLNLRHTEVLPLYARLSNSEQNR
                     VFQSHSGRRIVLATNVAETSLTVPGIKYVIDPGTARISRYSYRTKVQRLPIEPISQAS
                     ANQRKGRCGRVSEGICIRLYSEDDFLSRPEFTDPEILRTNLASVILQMTALGLGDIAA
                     FPFVEAPDKRNIQDGVRLLEELGAITADEQQTAYKLTPLGRQLSQLPVDPRLARMVLE
                     AQKHGCVREAMIITSALSIQDPRERPVDKQQASDEKHRRFHDKESDFLAFVNLWNYLG
                     EQQKALSSNQFRRLCRTDYLNYLRVREWQDIYTQLRQVVKELGIPVNSEPAEYREIHV
                     ALLTGLLSHIGMKDADKQEYTGARNARFSIFPGSGLFKKPPKWTMVAELVETSRLWGR
                     IAARIEPEWVEPVAQHLIKRSYSEPHWERAQGAVMATEKVTVYGLPIVAARKVNYSQI
                     DPALCRELFIRHALVEGDWQTRHAFFRENLKLRAEVEELEHKSRRRDILVDDDTLFEF
                     YDQRISHDVISARHFDSWWKKISRETPDLLNFEKSMLIKEGAEKISKLDYPNFWHQGN
                     LKLRLSYQFEPGADADGVTVHIPLPLLNQVDESGFEWQIPGLRRELVIALIKSLPKPV
                     RRNFVPAPNYAEAFLGRVTPLELPLLDALERELRRMTGVTVDREDWHWDQVPEHLKIT
                     FRVVNDKNKKLQEGRSLAELKNALKGKVQETLSAVADDGIEQSGLHIWSFGELPESYE
                     QKRGNYKVKAWPALVDERDSVAIKLFDNPLEQQQAMWCGLRRLLLLNIPSPIKYLHEK
                     LPNKAKLGLYFNPYGKVLELIDDCIACGVDKLIDANGGPVWSEAGFTALHEKVRAELN
                     DTVVDIAKQVERILTTVFNINKRLKGRVDMSMALGLSDIKAQMSGLVYRGFVTGNGFK
                     RLGDTLRYLQAIEKRLEKLAVDPHRDREQMLKVESVQQAWQQWINKLPPARREDDDVK
                     EIRWMIEELRVSYFAQQLGTPYPISDKRILQAMDQITA"
     gene            14431..15231
                     /locus_tag="OPV72_002693"
     CDS             14431..15231
                     /locus_tag="OPV72_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HCR9914946.1"
                     /translation="MNTTPFPALSAETLLAVNTVGQWLAQNDFSGEQPYSSDCVVLAG
                     NAVIPTIDAACRIAKAQGVPLLISGGIGHSTPFLYAVIARHPRYHTIRTTGRAEAAIL
                     ADIANQFWHIPAEKIWLEDRSTNCGENARFSCALIRQAKENINTAIVVQDPTMQRRTI
                     AAFRRVTNDDTDAPRWLSFPGFVPVLRHLNGGTRFANVEEGIWTVERYLSLIAGELPR
                     LRDDETGYGPRGKDFIIHVDIPRDIEKAWQVLQADTTLRSALEQRALR"
     gene            15348..15878
                     /gene="cybB"
                     /locus_tag="OPV72_002694"
                     /pseudo
     CDS             15348..15878
                     /gene="cybB"
                     /locus_tag="OPV72_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460598.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b561"
BASE COUNT         3749 a         4074 c         4395 g         3796 t
ORIGIN      
        1 ccaggttaat ccttagaatg ttttttaatc tgcgctgggt ttttccgctt ttcctgccag
       61 caaggcaaga aagtcatagc gtttttgcaa atccaatgcg gcatctcgcc ataattgttc
      121 agctacttca ggctgttgcg cattcaggcg acggaaacgc tgttcattaa gcaacgtttc
      181 cgctagggca tcagacggtg gccgagagtc cagcgccagc ggcggcttgc cttcatccgc
      241 acggcgggga tcaaagcggt ataacggcca gaaaccggtc gccgttaact ggcgcatctg
      301 gtcatggctt agcgccagat cgtagccatg ttcctcacag ggactatagg caatgatcag
      361 cgacggtcct ggccaggctt cggcctcctg gatggctttc accgtctggt ttaactgcgc
      421 gcccagcgaa atttgcgcga cataaacatg accatacatc atcatgctga cgccaagatc
      481 tttacgggct ttacgcttgc catgttcgcc aaacttagtg acggcgccaa gcggcgtcgc
      541 cttcgacgcc tggccgccag tattggaata acactgcgta tccagaacca gaatattgac
      601 attctccgtc aggcttaaca catggtctaa accgccaaag ccgatgtcgt atgcccaacc
      661 atcgccgcca atcagccaga ttgatttttc taccagcgca tcagcatctt ttaacagttc
      721 ctctgcgccc gcaaccgatt tcagatgttg gcgtaatgcg gcgacctgtt cacgccgaac
      781 gtcaggcgtt gcttcggcat gcagcgcatc gtttaattcc gccggaatgc gatcggcgaa
      841 ttgcgccagt aaacgcatga cgcgcgcccg gtgctgatcc acactcagac ggaaaccgag
      901 gccaaattcc gcgttatctt caaatagcga attcgtccac gccgggccgc gtccgttggc
      961 atcggtggta taaggcgtag agggtaagtt accgccgtaa atagaggaac accccgtggc
     1021 gttagcgatt aacattctgt cgccatataa ctgagtcagc agtttaatat acggcgtttc
     1081 accgcagccg gaacaggcgc cggaatattc aaacagcggc gtaatgagct gcgatgtgcg
     1141 gatatcaatc cgttccagtt tgctgcgatc gatttccggc aagtcgagga agaagtcata
     1201 attcactttc tcttcttcca catgctcaag gcgcgacatc atgttaatcg ccttgatctg
     1261 tggattttgc cgatctttag ccgggcagac ctctacgcat aaattacagc cagtacagtc
     1321 ttccggcgcg acctgcagca catatttctg gccgcgcata tcgcgggact tcacgtccag
     1381 cgaatgcaga ctggctggcg cgttctccat cgcctgcggg gaaacgactt tcgcacgaat
     1441 cgccgagtga gggcaggcgg cgacgcagtg attacattgt gtacacagtt cctctttcca
     1501 gacaggaatc tcttcggcga tattgcgttt ttcccagcgg gtggtgccca ttggccatgt
     1561 tccgtccggc ggcagcgcgg aaacaggcag tgcgtcgccg aggcccgcca acatggcggc
     1621 ggtaacggtt ttcacgaaat ccggcgcggc gtcggagacg accggcgggc gatgcgcgct
     1681 gtgtggatta accgcctgca acggcacttc cgccagcgat tcctgcgcca gagccaatgc
     1741 ctgccagtta cgctcaacca gatcctgacc tttgctgcta tagcttttgg caatcgcgcc
     1801 ctgcagctca accagagcgc tatcgcccgg aagaatatgc gtcaggtgga agaacgccat
     1861 ttgcatgacg gtattgatgc gggcgcccag tccacattcg cgggcgattt tcgccgcgtt
     1921 gaccacgtaa aaacgcgcct ttttctgatt caataccgcc tgaacttctt gcggcagacg
     1981 cgaccagacc tcgtcggcgc tgtacggcgt attaagcaga aagataccgc ctggcttcag
     2041 acgctccgcc atctgatatt tatcgataaa ctgtaattga tggcagccga caaaatccgc
     2101 ctgagcaatt aagtaagcgg aacgaatggg tttttcgctg acgcgcaggt gcgataccgt
     2161 gagtccgcca gcttttttag agtcataaac gaaataacct tgcgcatacc acggcgtaga
     2221 attaccgata attttaatat tatttttcgt ggcggatacg ctgccgtcgc ttcccagacc
     2281 gtaaaataac gcttccagtt tagcgctgcc gggcagggta ttttccggta atggcagcga
     2341 gagattagtg acgtcatcat aaatgcccac cgtaaaccgt ggcttgggtt tcgcgcggct
     2401 gagttcatta aagaccgcca gtacgcacgc cgggccgaac tctttggatg atagcccata
     2461 acggccgcca atggtgcgcg gcaatgtttc gcgctcgcca ttattaaagg cttccgccag
     2521 tgcggtcatc acgtccagat aaagcggctc ggcctgggcg ccaggctctt tggtgcgatc
     2581 cagcacggcg atagcgcgaa cggtttccgg taatgcttgt aacaaatgtt tggcggagaa
     2641 ggggcggaac agacggactt tcagaacgcc gaccttttct ccgcgtatca gtagctcgtc
     2701 cacgacctct tcgcaggtgc cgagggcgga gcccatcata atgatgaccc gttcagcctg
     2761 gggatgacca taatattcaa atggctggta ctggcggcct gtagcatcgc caaatgcctt
     2821 catcgcctct tcaacatgat cataaacggc gttgtaccac gggttggtcg cttcgcgaga
     2881 ctggaagtag gtatccggat tcgcagaagt tccacgaatc accggatgct ccggattcag
     2941 cgcgcgggcg cggtgagcgt cgatctccgc ctgcggcatc aggttcagaa tggtttcatc
     3001 cgttagcggt ataattttgt tgatttcatg cgatgtacgg aagccatcaa aaaaatgaat
     3061 aaacggaacg cggcttttca gcgtagccct gtgcgcgatc agcgcaaaat cctgcgcttc
     3121 ctgaacgctg gcggcgcata acatcgcgca gcctgtctgg cggaccgcca tcacatcgga
     3181 atggtcgcca aaaatagaaa gcgcgtgtgt ggcgacggtg cgtgcggcaa cgtgcagtac
     3241 aaacggcgtg agctgccccg ccagtttata cagcgttggg atcatcagca gcagcccctg
     3301 cgatgatgta aatgacgtag aaagcgaacc ggtttgtaac gcaccgtgaa cggcggcgat
     3361 cgcaccgcct tccgactgca tctctaccac acgcggcgta tcgccccaga catttttaag
     3421 cccattgccg gcccaggcat ccgcttgttc agccattgtt gaactgggcg taatcgggta
     3481 aatggcgata acctcgctgg tacggaacgc caccgacgct actgcgccat taccgtcaat
     3541 cgtttgcata tgacaccctt acattgcgca aaaaagaggg acacgcataa tcgtgagcgt
     3601 atcctgtagt tatcctttta ttttagcaaa gcccttcaag ccccattttc gcttttgtgt
     3661 ccctggcggg aggagaatgg cgatttcttg ccgaaaagac gtaaaaaatt gccaataaat
     3721 gttaatgaag cgcataaatg cgcgctttgc ctctcgacgc gtcagtttct gctgcctatt
     3781 atttagggcg gtgtcgtttg gatgaataaa cagaggggag agaaatgcgc gcagcgtttt
     3841 gggtgggatg tgccgcgtta ttattgtcgg cttgcagtag cgaacctgtt cagcaggcaa
     3901 ctgcggcgca tgtttcgcca gggatgaaag cggcgatgtc cagcgccggc gaagcgaatt
     3961 gcgctatgat tggcggttcg ctttcagcgg cccggcagct tgatggttca gtaattggta
     4021 tgtgcgcgct acccaacggc aaacgttgta gcgaacagtc gcttgccgcc ggaagctgcg
     4081 ggagttatta agcgcggcgt ttcgcctgac gcgtataact tttcacttaa tggcttagtg
     4141 cgctaaatcc gccagtttat acattagcgt tgtttctgcc gtcgccagcg ttaattggtt
     4201 cgcagttaaa tcgacttgcg ctcctttgct gaagagctcg ctgagggtgc cgtccagcgc
     4261 attaagctgc ggatcggcgc acatcattcg ggtcatcgct aaatttttca cttttaattc
     4321 gccgtccgat agttttcctt cgccggtgaa ttgattgcac attttgccgg ataccgtcat
     4381 gtcctcgcca aagctgagct ccgggccggt gaccgtttta ccgtttacgc tttccagaac
     4441 aaagcggtgg tgctccagtt gctcgcgttt gacggacact tttccactgc tcacacaccc
     4501 tgtcattatg atgctcaggg cgaccagcgt gacgattttc ttcattgata ttctctgtaa
     4561 tctgatagtt aacactgact atagtaatga tatgaccgga tagatcttca ggggttatcc
     4621 gaaaatgctc ctctgagcgc aggggagcga caggattaga acagcgcgtt cgggcaggct
     4681 tcgcccttct caagctggct taagttttgt aacgtggttt cagagatgct gatcagcgct
     4741 tctgcggtca ggaatgcctg atgccccgta aacagtacgt tatggcaggc cgacagacgg
     4801 cggaaaacat catcctgaat aacatcgttt gacttgtcct caaagaacag gtcgcgttcg
     4861 ttttcataca catccatccc cagcgagccg attttctgat tcttcagagc ttcgatagcc
     4921 gcctgggaat caatcagcgc gccacgactg gtattaatga tcataacgcc atttttcatt
     4981 tgatcgaatg ccgcatggtt cagtaaatgg tagttttccg gcgtgagcgg gcagtgcagg
     5041 gaaatgacat ccgattcggc aaacaacgtt tgcagatcca catactcgac gccgaggtca
     5101 agcgcggcag tgctgggata gggatcaaac gccagtaaac gcattccaaa gcctttcagg
     5161 atacgcagcg cggcgacgcc gattttaccg gtaccaatga cgccagcggt ttttccgtgc
     5221 atggtaaagc cggtcagtcc ctcaagggaa aagttagcgt cgcgggtgcg ttgataagcg
     5281 cggtgaatac ggcggttcaa tgtcatcatc atgccaatcg catgttcagc gacggcttcc
     5341 ggagaataag ccggtacgcg caccacctgc aagccgagtt ctttagcggc atccaggtcg
     5401 acattattaa atccggcgca acgcagcgcg atgtatttca cgccgtgttt tttcagctct
     5461 tccagtaccg gtcggctccc gtcgtcattc acgaagatac aaactgcttc acatccattg
     5521 gcggttttcg ccgttttctc ggttagcaga aaatcaaaaa actccagttc aaaaccgaac
     5581 gcttcgttca cttgctgtag atatttcttg tcatactgtt tggtactata gacggcgagt
     5641 ttcatatgac cttctccagt gatgttagaa tcacacaaat atgcttaaaa ttatcttaca
     5701 aaaaatcaaa aataattgat agtcatacat atgatgaata attttaggtt atcattctcc
     5761 acgacgcctc aaatagtcgg agggcggccc tgcaacacgc ataacgtatc acccgtttgc
     5821 aacatgaact attaggctat gtacgggcaa tcatgccaaa ataaagagat agccgactga
     5881 atttttcgtt aaatcaggaa attaatggcc catgaagggt aaatataaag ccgcccttgc
     5941 gctactgtta ctgctgattc ttgtccctct gacgctactg atgaccctcg ggctgtgggt
     6001 tcccactctg gcgggaattt ggctacccgt cggtacccgt atcgctctgg aacaaagtcc
     6061 acgcctgaca cgtcatgggt tagtgattcc cgatcttcgc tatctggtca atgattgttc
     6121 gttagcgcat attacccagg cggaactgac gcatcccagc cgttggttgc tgaatattaa
     6181 aagcctcaaa ctggatgccg catgcctggc gaaactgccg gcttcggaag cttctcccgc
     6241 cgcgccgcgt acgctggcgc agtggcagtc aatgctgccc aatacctgga ttaacatcga
     6301 taatgtcatt ctcgcgccct ggccggaatg gcagggcaag ctggcgatct ccatgacgcc
     6361 ggtcattcag cagatacgtt atcagggcga aaaagtaaaa tttcaagggc agctacgcgg
     6421 tcaggcattg acggtgagcc aactggagat cgccgcgctg gccaaccagc ctcccgttag
     6481 cctggcgggg gagtttatgt tgccgctggt accggatggc ctgccggtca gcggtcatgc
     6541 ggcagcgacc ttgcgtctgc cgcaggaacc gtcgctggtg gatgcggaac tggagtggcg
     6601 tgataatgcc ggacagctca tcgtgatggc gcgaggtaat cctgatccga ttctcgatct
     6661 cccctgggcg gtaacgcgtc agcggcttac cgtcagcgat ggccgctgga actggccata
     6721 tcagggattc cccttgagcg gacgtctggc ttttaatatc gataactggc aagccgggcc
     6781 ggataatgcg cgagtcagcg gacgcctgaa tattctgacc cagggcgatg ccggtaaagc
     6841 gaacgcggta ctgactatcg gcccgggaaa actcagcatg gatagcagtg agatgcctct
     6901 acagcttacc ggcgaggcta aacagaagga tttaatcttt tatgccgtat tgcccgctat
     6961 gttccgcggc agtctggccg atccgcagct cacctttgca cctggcgcat tgctacgctc
     7021 acgcggacgg gtgattgatg cgttagatat tgatgaaatt cgttggccgc tggcgggcgt
     7081 taaggtaacg ccgcgcggcg ttgatggtcg attacaggct attttacggg cgcacgaaaa
     7141 tgagatgggc gatttcgttc ttcatcttga tggcctggcc aatgattttc tccctgatgc
     7201 tggtcgctgg cggtggcgct attgggggca aggaagcttt acgccaatgc gcgcccgctg
     7261 ggatattgcc ggacagggcg aatggcatga taacaccatc aggttgacca gtttgtccac
     7321 cggttttgat cagttgcact atggcgcaat gaccgtcaca tcgccaagac tggcgctgga
     7381 taaacctatt gtctgggttc gcgacgccac aacgccgtcg ctacagggcg cgctgtctct
     7441 ggaggcggga aaaaccgtat ttaccagcgg gagcgtgctg ccgccttcta cccttaattt
     7501 tagcgttgaa gggcgcgagc caaccctgtt ccagtttaaa ggcgaccttc gggcgggggc
     7561 gatagggccg gtacggctga acgggcgctg ggatggcgaa cgccttcgcg gacaggcctg
     7621 gtggccgaag cagtcgctta tcgttttcca gccgttgctt ccaccggact ggaaaatgac
     7681 gctgcgcgaa ggctcactgt atgcgcaggt ggctttttcc gctgcgcagg ggcagggatt
     7741 tgaagcaggt ggacacggcg tgttaaaggg cggtagcgcc tggatgccgg ataacaaaat
     7801 caacggcgtc gatttcattc tgccatttcg cttccacaac ggcgcgtggc aattggggac
     7861 gcgcgggccc gtctcgctgc gtattgccgg gatagtcaac caggtcacgg cgaaaaatat
     7921 caccgccgat ttacagggcg gttatccctg gagcgagtcg aatccattac tgctaagcga
     7981 tgtcagcgta gacgtgctgg gcggtcaaat tattatgaaa cagttgcgaa tgccgcagca
     8041 cgacccggcg cttttgcggg tgcaaaatat ttcatccagc gaattgatta gcgccataaa
     8101 tccaaagcaa ttcgccatgt ctggtccggt tagcggcgcg ctgccgctgt ggctgaacaa
     8161 tgaaaaatgg ataatcaaag atggctggct tacgaatcct gggccaatga cgttgcgtat
     8221 cgataaagat actgcggatg cggtggtgaa ggataatgtc acggcaggct cggcgattaa
     8281 ctggctacgt tatatggaga ttacgcattc gtggacaaaa attaacgttg ataacctggg
     8341 cgtactaacg atgcaggcgg ccattaccgg caaaagccgg gtagatggta aaaccgcgat
     8401 cgttaacttg aactataccc atgaagaaaa tgtgtttacg ctgtggcgca gtttgcgttt
     8461 tggcgacaat ttacaggcat ggcttgaaca aaatacagcg ttgccgcaac ctccttgccg
     8521 gaaagacaag gactgtgagg ataaataatg aaaatgagta ttgccatgct gtcagcgctt
     8581 gcgtcattta tcgtggtggg gtgcacgcca cgtattgaag tcgccgcgcc ggaacagccg
     8641 attaccatca acatgaatgt aaagatcgag catgaaatac atatcaaagt cgataaagac
     8701 gttgaagaac tcctgaaatc acgcagcgat ctattctgag gccataatga aaaagtattt
     8761 aatactatgg gtgctgacgc tgagcttgct cacaccttct gtgtgggcct taaccctgga
     8821 cgaagcgcgc acgcagggcc gggtcgggga aacgctgaat ggctatctgg tggccttaaa
     8881 gaatgatgcc gaaacccaga agctggtgct tgatatcaat catgcccgtc gcgccagtta
     8941 tcagcagtta gcggatagca atcatcttcc cgtggatgag gtggcgaaga tggcagggca
     9001 aaaactggtt aagcgcgcca ggccgggaga atatgtccag ggaattaatg gcaaatggat
     9061 gcgtaaataa ccgcttcccg acaatttttt taccgcaaaa tgcattttta tatgggtaat
     9121 ttttgaatac ggaggtcgta tttacattag gcgaaccgga aggctatttc tatactgtcg
     9181 actggtatca ctattcgcgt gagtaaccag gtatgacgtc tgaaaaatta tctgctgcct
     9241 gccattgtgg cagcgtcgtg tttaccgttc aacttagcga tggctttcat accgccaggc
     9301 gctgcaactg ttcgttttgc cggatgcgcg gagcggtggc agtgtctgcg ccgctatcgg
     9361 gtattaaagt gctaaaaggg caggataagc ttaccgaata tcgcttcaat acgggcaagg
     9421 cggtgcattt tttctgttcg gtatgcggga tatatacttt tcatcagcgc cgatccaatc
     9481 ccgatcaata tggggtcaat gtggcgtgca ttgaaaatgt gtcgcctttt gatttcgcct
     9541 gcgttgaagt caatgatggg gtaacgcatc ccagcgatgg cggcagtagc ggcgtggtag
     9601 gatatttgcg ctacgaacct aagaagtcac ctcccgtcga aacgggaggc aaaaatattt
     9661 aagcggccac gacgctgtca atcgcggctt ttgcatcggc ctgggcttta gctgccactt
     9721 ccggcccgta ggcgatgcct tcggcaaaga caaaattcac gtcggtgata ccgataaaac
     9781 caaggaacac tttcaggtaa ggcgcaatca aatccgtcgg ggtgtcttta tggataccgc
     9841 cgcggctgga gagaaccacc gcgcgtttgc cggttaccag accttccggg cctttttcgg
     9901 tatagcggaa agtgataccg gcgcgggcaa tcagatcaaa gtagtttttc agctgcgtcg
     9961 ggatattgaa attgtacatc ggtgccgcaa taacgatgac gtcgtgggct ttcagttcag
    10021 caatgagttc atcagacagc gccagagcgt cctgctgacg tggcgttaaa ggcgcatcgc
    10081 ccggacgcat cgcgcccacc agctcgccat ccagcaccgg aacagggttg gccgccagat
    10141 cgcggacagt aatttcatct gcgacgtgtt tttcgcgcca ttgttcaata aaatagtcag
    10201 tcaactgacc agactgagag taccctgcca gaatactgga tttaagaact aataccttgc
    10261 tcatgggtgt ttccttttat gtgtttgaag gggcgtgccc cgttgcttgt tgacacttta
    10321 ttcacaaata tgtcgcaggg atagcgcaat atatcgaacc ctttgttcga aattattgaa
    10381 caacacaaaa aaagccccaa tgtggtactc tatacctatc atttaaaacg attttaaaca
    10441 ggcagaatgc tgcccaagag ctttatgact gaacaatcta cgttgacgct tcaggtgtta
    10501 cagcagcggc tggatgcact gatgctgcgc gacaaacagc gcttttcgcg ccgcctgcat
    10561 ggcgtaaaga aagtaaaaaa tcctgatgcg caacaggcca ttttccagac gatggcgaaa
    10621 gaaattgaac aggctgcgac gcaggtcgct ctccgcgaag cggcgcgccc ctcaatcact
    10681 tatccgcaaa atctgcctgt tagccagaag aaacaggaca ttctggaagc ggtccgcgat
    10741 catcaggtgg tgatcgtggc aggggaaacc ggttccggta aaaccaccca gttgccgaaa
    10801 atttgtatgg aactgggacg cggaattaaa ggacttattg gacatactca accgcgtcgt
    10861 ctggcggcgc gcaccgtcgc taaccgcatt gccgaagagt tgcaaacgga gcctggcggc
    10921 tgcatcggct ataaagttcg tttcagcgat catgtcagta gcaacaccat ggtcaaactg
    10981 atgacggacg gtatcctgct ggcggaaatc cagcaggaca ggctattgat gcagtacgac
    11041 accatcatta ttgatgaagc gcatgaacgc agcctgaata ttgacttctt gctcggctat
    11101 ctgaaagagc ttctgccgcg tcgccccgat ctgaaagtga ttattacctc tgcgaccatc
    11161 gacccggaac gcttctcgcg ccactttaat aacgcgccga ttatcgaagt ctctggccga
    11221 acgtatcccg tagaagttcg ttatcgcccc atcgtggaag aggctgacga cactgaacgc
    11281 gatcagctac aggcaatttt cgacgctgtt gatgaactgg ggcgtgaaag tcctggcgat
    11341 atcctgattt ttatgagcgg agagcgggaa atccgcgata ccgccgatgc cctgaacaag
    11401 ctgaacttac ggcataccga agtgttgccg ctgtatgcac gcttgtcgaa cagcgaacag
    11461 aaccgcgttt tccagtcgca cagcggacgc cgtatcgtgc tggcgactaa cgtggcggaa
    11521 acctcgctga cggtgccggg tatcaaatat gtgatcgatc ctggcactgc gcgcatcagc
    11581 cgctacagct accgcactaa agtgcagcgc ctgccgattg aaccgatctc acaggcttcc
    11641 gccaatcagc gtaaagggcg ttgcggacgc gtatcggaag ggatctgcat tcgtctgtat
    11701 tcggaagatg actttttgtc acgcccggaa tttaccgacc cggaaattct acgtaccaac
    11761 ctggcgtcgg ttattttgca gatgaccgcc ctgggactgg gtgacatagc cgccttcccg
    11821 tttgtcgaag cgccggataa gcgcaatatt caggatggcg tgcgtttgtt ggaagagctg
    11881 ggggcgatta ccgccgacga acagcaaacg gcatataagc tgacgccgct gggccgacaa
    11941 ttatcccagt tgccggtcga cccgcgcctg gcgcgtatgg ttctggaagc gcaaaaacat
    12001 ggctgtgtgc gcgaagcgat gatcattact tccgcactct ctattcagga tccgcgcgag
    12061 cgcccagtgg ataagcagca ggcttccgat gagaaacacc ggcgtttcca tgataaggaa
    12121 tccgattttc tggcgtttgt taacctgtgg aattacctcg gcgagcaaca aaaggccctg
    12181 tcgtcgaatc aattccgccg tctgtgtcgc accgactatc tgaactattt acgcgtgcgt
    12241 gagtggcagg atatctatac ccaactgcgt caggtggtaa aagaactggg gattccggta
    12301 aacagcgaac ccgcagaata ccgggaaatt cacgttgcgt tgttaacggg gctgttgtcg
    12361 catatcggga tgaaagatgc cgataaacaa gagtacaccg gcgcgcgtaa cgcccgattc
    12421 tctattttcc ccggatccgg tttattcaaa aaaccgccga aatggacaat ggtcgccgag
    12481 ctggtggaaa ccagccgttt gtgggggcgc atcgctgccc gcattgagcc agaatgggtg
    12541 gaaccggtag cccagcacct gattaaacgt tcatatagcg aaccgcactg ggagcgggcg
    12601 caaggcgcgg tgatggcgac ggaaaaggtt actgtctacg gtctgccgat tgtcgccgcg
    12661 cgcaaggtga attatagcca gattgacccg gcgttgtgtc gcgagttgtt tatccgccat
    12721 gcgctggtgg agggggactg gcaaacccgt cacgccttct tccgtgagaa tctaaaattg
    12781 cgtgcggaag tcgaggaact tgagcacaaa tctcgccgcc gcgatatcct ggtggatgac
    12841 gataccctgt ttgagtttta tgaccagcgt attagccatg acgttatttc cgcccgccac
    12901 tttgatagtt ggtggaaaaa aatcagccgc gagacgccgg atctgctcaa ctttgaaaaa
    12961 agtatgctga ttaaagaagg cgcggaaaaa atcagcaaac tggattaccc gaatttctgg
    13021 caccagggca atctcaagct gcgtttgagc tatcagtttg aaccgggcgc ggatgctgac
    13081 ggcgtgaccg tccatattcc gttgccgcta cttaaccagg ttgacgagag cggttttgaa
    13141 tggcagatcc cagggctgcg ccgtgaatta gtgattgcgc tgattaaatc gttgccaaaa
    13201 ccggtacgtc gcaactttgt tccggcgcca aactatgctg aagcgttttt aggtcgcgta
    13261 acgccgctgg agctgccgct gctggacgct ctggagcgtg aactgcgccg gatgaccggc
    13321 gtcacggtcg atcgggaaga ctggcattgg gatcaggtgc ccgagcatct gaaaatcacg
    13381 tttcgcgtgg tgaatgacaa aaacaagaaa ctgcaggaag ggcgttcgct cgccgagctt
    13441 aaaaatgcgc tgaaaggcaa agtgcaggag acgctctcgg cggtagcgga tgacggcatc
    13501 gagcagagcg ggctgcatat ctggagtttc ggcgagctgc cggaaagcta cgaacagaaa
    13561 cgcggtaatt ataaagtgaa ggcgtggccg gcgttagtgg atgagcgtga cagcgtcgct
    13621 atcaaattgt ttgataatcc gctggaacaa caacaggcga tgtggtgcgg tttacgccgt
    13681 ctgctgttgc tcaatattcc ttcaccgatt aagtatctgc atgagaaatt gccgaataaa
    13741 gccaagctgg ggctgtactt taacccgtac ggcaaagtac tggagttgat tgatgactgt
    13801 atcgcctgcg gggtagataa gctgatagat gccaacggcg ggccggtgtg gagcgaagca
    13861 ggtttcaccg cgctgcacga aaaggtacgc gccgagctga atgatactgt ggtggatatc
    13921 gcgaagcagg ttgagcggat cctgacgacc gtattcaata tcaataagcg tctgaaaggg
    13981 cgggtggata tgagcatggc gttggggctt tccgatatca aggcgcagat gagcggtctg
    14041 gtataccgtg gttttgtgac tggcaacggc tttaaacgtc tcggcgatac gctgcgttat
    14101 ctgcaggcaa ttgaaaagcg gctggagaaa ctggctgtcg atccgcaccg cgatcgggag
    14161 caaatgctga aagtcgaaag cgtccagcag gcgtggcaac aatggataaa taaattgcct
    14221 ccagcgcgtc gcgaagatga tgatgttaaa gagatccgtt ggatgattga agaactgcgt
    14281 gtcagttatt tcgcccaaca gctcggtacg ccttatccta tttccgataa gcgtatttta
    14341 caggccatgg atcagattac ggcctaaaaa gccaggcgac gatatctttc aaagagatcc
    14401 ggtacaagtt cggaacaaaa aggaggaatt atgaatacaa cgccatttcc ggcgctctct
    14461 gcggaaacat tgctggcggt gaataccgtc ggacagtggc tggcgcaaaa tgatttttcc
    14521 ggcgaacaac cttattcgtc ggattgcgtc gtcctggcgg gcaatgcggt gatccccact
    14581 atcgacgcgg cctgtcgcat cgccaaagcg caaggcgttc ctttactgat tagcggcggt
    14641 ataggtcatt cgacgccgtt tttgtacgcc gtgattgccc ggcatccgcg ctaccatact
    14701 attcgcacaa ccggacgcgc tgaagccgct atcctcgcgg atatcgcgaa ccagttctgg
    14761 catattccgg ctgagaaaat ttggctggaa gatcggtcaa ctaattgcgg cgaaaatgcc
    14821 cgtttctcct gcgcactgat ccgtcaggcg aaagaaaaca ttaacacggc tatcgttgtg
    14881 caagacccca ccatgcagcg gcgcactatc gcggcgtttc ggcgcgtgac aaacgacgac
    14941 accgatgcgc cgcgctggct gagttttcct ggttttgttc cggtactgcg ccaccttaac
    15001 ggcggtacac gttttgccaa cgttgaagag ggcatctgga cggtggagcg ttatctgtct
    15061 ctgattgccg gcgagctgcc acgtttgcgt gacgatgaaa cagggtatgg accgcgtggt
    15121 aaagatttta tcattcacgt tgatatccca cgcgatattg aaaaggcatg gcaggtattg
    15181 caggcagata cgacgctgcg cagtgcgtta gaacagagag ctttacgcta aaaatcgccc
    15241 gtttgcgagg gtgaacgggc aagtgcgacc accatttcat aaatttgatg aattatttat
    15301 aaaagctggt tatgttgtcg ctttacggtt ttcattcagg acgcgctatg ggcaataagt
    15361 attccggcct gcaaattggt attcactggt tagtcttttt tctggttatt gtggcttacg
    15421 ccgcgatgga gctacgcggt tttgcgccgc gtagttatcg gccctagttt aatatgacgc
    15481 atgtttcatg tggtatcact attttgcttt taatggtggc gcgcttgatt attcggctga
    15541 aatatcccac gccgcccatt gttcctcgtc caaaaccgat gatgaccgga atggcgcatt
    15601 taggacatct ggtgatttac ctgttattta tcgtgctgcc tgttattggt ctggtcatga
    15661 tgtataaccg cggcaatccc tggttcgcat ttggcattac tatgccgcat gccgccgaag
    15721 ctaactttga acgcgtagat atgctgaaat cctggcacgt cacgctggcg aatctgggct
    15781 attttgttat tggacttcat gccatcgctg ctttgatgca tcactatttc tggaaagaca
    15841 atacgctgtt acggatgatg ccgcgtaagc gtaactgacc gtcctgtatg acgtttgcta
    15901 caggcggggt taactgcttt aggcaaacaa ggcatctatc agaggggatg gcgtattcca
    15961 tacagaaaac gcctgcgtct aaccaggacc cgtgacgcag gcgaaggagg acgg
//
LOCUS       DAJVBX010000102        15859 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.102, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000102 DAJVBX010000000
VERSION     DAJVBX010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 15859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15859
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.102"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(253..1059)
                     /gene="trpA"
                     /locus_tag="OPV72_002695"
     CDS             complement(253..1059)
                     /gene="trpA"
                     /locus_tag="OPV72_002695"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HCR9914947.1"
                     /translation="MERYENLFAQLNDRREGAFVPFVTLGDPGIEQSLKIIDTLIDAG
                     ADALELGVPFSDPLADGPTIQNANLRAFAAGVTPAQCFEMLALIREKHPTIPIGLLMY
                     ANLVFNNGIDAFYARCEQVGVDSVLVADVPVEESAPFRQAALRHNIAPIFICPPNADD
                     DLLRQVASYGRGYTYLLSRSGVTGAENRGALPLHHLIEKLKEYHAAPALQGFGISSPE
                     QVSAAVRAGAAGAISGSAIVKIIEKNLASPEQMLAELRSFVSAMKAASRA"
     gene            complement(1059..2252)
                     /gene="trpB"
                     /locus_tag="OPV72_002696"
     CDS             complement(1059..2252)
                     /gene="trpB"
                     /locus_tag="OPV72_002696"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HCR9914948.1"
                     /translation="MTTLLNPYFGEFGGMYVPQILMPALNQLEEAFVSAQKDPEFQAQ
                     FADLLKNYAGRPTALTKCQNITAGTRTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG
                     KSEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVH
                     SGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILD
                     KEGRLPDAVIACVGGGSNAIGMFADFINDTSVGLIGVEPGGHGIETGEHGAPLKHGRV
                     GIYFGMKAPMMQTADGQIEESYSISAGLDFPSVGPQHAYLNSIGRADYVSITDDEALE
                     AFKTLCRHEGIIPALESSHALAHALKMMREQPEKEQLLVVNLSGRGDKDIFTVHDILK
                     ARGEI"
     gene            complement(2262..3620)
                     /gene="trpCF"
                     /locus_tag="OPV72_002697"
     CDS             complement(2262..3620)
                     /gene="trpCF"
                     /locus_tag="OPV72_002697"
                     /EC_number="4.1.1.48"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional indole-3-glycerol-phosphate
                     synthase TrpC/phosphoribosylanthranilate isomerase TrpF"
                     /protein_id="HCR9914949.1"
                     /translation="MQTVLAKIVADKAICVEARKQQQPLASFQNEIQPSTRHFYDALQ
                     GARTAFILECKKASPSKGVIRDDFDPARIASIYQHYASAISVLTDEKYFQGSFDFLPV
                     VSQSAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDEQYRQLSAVAHSLKMGV
                     LTEISNDEERERAIALGAKVVGINNRDLRDLSIDLNRTRQLAPKLGHGVTVISESGIN
                     TYGQVRELSHFANGFLIGSALMAHDDLNAAVRRVLLGENKVCGLTRAQDAKAACDAGA
                     IYGGLIFVPSSPRAVSVEQAREVISGAPLQYVGVFKNADIADVCQKAAVLSLSAVQLH
                     GSEDQAYVNALREALPRNVQIWKALSVSNALPARDYHHVDKYIFDNGQGGSGQRFDWS
                     LLQGQPLDDVLLAGGLAADNCVQAAQVGCAGLDFNSGVESQPGIKDARLLASVFQTLR
                     AY"
     gene            complement(3624..5219)
                     /gene="trpD"
                     /locus_tag="OPV72_002698"
     CDS             complement(3624..5219)
                     /gene="trpD"
                     /locus_tag="OPV72_002698"
                     /EC_number="2.4.2.18"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008784940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional anthranilate synthase glutamate
                     amidotransferase component TrpG/anthranilate
                     phosphoribosyltransferase TrpD"
                     /protein_id="HCR9914950.1"
                     /translation="MADILLLDNIDSFTWNLADQLRTNGHNVVIYRNHIPAQTLIDRL
                     ATMKNPVLMLSPGPGIPSEAGCMPELLTRLRGKLPIIGICLGHQAIVEAYGGYVGQAG
                     EILHGKASSIEHDGQAMFAGLANPLPVARYHSLVGSNVPAGLTINAHFNGMVMAVRHD
                     ADRVCGFQFHPESILTTQGARLLEQTLAWAQQKLEPTNTLQPILEKLYQAQTLTQQES
                     HQLFSAVVRGELKPEQLAAALVSMKIRGEHPNEIAGAATALLENAAPFPRPDYLFADI
                     VGTGGDGSNSINISTASAFVAAACGLKVAKHGNRSVSSKSGSSDLLAAFGINLDMNAD
                     KSRQALDELGVCFLFAPKYHTGFRHAMPVRQQLKTRTLFNVLGPLINPAHPPLALIGV
                     YSPELVLPIAETLRVLGYQRAAVVHSGGMDEVSLHAPTIVAELHDGEIKSYQLTAEDF
                     GLTPYHQDQLAGGTPEENRDILTRLLQGKGDAAHEAAVAANVAMLMRLHGQEDLKANA
                     QTVLDVLRNGTAYDRVTALAARG"
     gene            complement(5219..6781)
                     /locus_tag="OPV72_002699"
     CDS             complement(5219..6781)
                     /locus_tag="OPV72_002699"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component 1"
                     /protein_id="HCR9914951.1"
                     /translation="MQTPKPTLELLTCDAAYRENPTALFHQVCGDRPATLLLESADID
                     SKDDLKSLLLVDSALRITALGDTVTIQALSDNGASLLPLLDTALPAGVENEVLPAGRI
                     LRFPPVSPLLDEDARLCSLSVFDAFRLLQGVVNIPTQEREAMFFGGLFAYDLVAGFEA
                     LPHLEAGNNCPDYCFYLAETLMVIDHQKKSTRIQASLFTASDLEKQRLNARLAYLSQQ
                     LTQPAPPLPVTPVPDMRCECNQSDDAFGAVVRQLQKAIRAGEIFQVVPSRRFSLPCPS
                     PLAAYYVLKKSNPSPYMFFMQDNDFTLFGASPESSLKYDAASRQIEIYPIAGTRPRGR
                     RADGTLDRDLDSRIELDMRTDQKELSEHLMLVDLARNDLARICTPGSRYVADLTKVDR
                     YSYVMHLVSRVVGELRHDLDALHAYRACMNMGTLSGAPKVRAMQLIADAEGQRRGSYG
                     GAVGYFTAHGDLDTCIVIRSALVENGIATVQAGAGIVLDSVPQSEADETRNKARAVLR
                     AIATAHHAQETF"
     misc_feature    complement(6804..6899)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00513"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Trp leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF00513"
     gene            complement(6876..6920)
                     /gene="trpL"
                     /locus_tag="OPV72_002700"
     CDS             complement(6876..6920)
                     /gene="trpL"
                     /locus_tag="OPV72_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_448140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trp operon leader peptide"
                     /protein_id="HCR9914952.1"
                     /translation="MAATFALHGWWRTS"
     gene            7042..7923
                     /gene="yciV"
                     /locus_tag="OPV72_002701"
     CDS             7042..7923
                     /gene="yciV"
                     /locus_tag="OPV72_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-3' exoribonuclease"
                     /protein_id="HCR9914953.1"
                     /translation="MGAALSDTNYAVIYDLHSHTTASDGLLTPETLVHRAVEMRVGTL
                     AITDHDTTAAIPAAREEISRCGLALNLIPGVEISTVWENHEIHIVGLNIDIAHPAMRD
                     FLAQQTHRRQARGRLIAERLEKAHIPGAWEGALRLANGGAVTRGHFARFLVECGKATT
                     MAEVFKKYLARGKTGYVPPQWCTIEQAIDVIHHSGGKAVLAHPGRYDLSAKWLKRLVA
                     HFADHHGDAMEVAQCQQSPNERTQLATLARQHHLWASLGSDFHQPCPWIELGRKLWLP
                     AGVEGVWQAWEQPQISQ"
     gene            7931..8551
                     /locus_tag="OPV72_002702"
     CDS             7931..8551
                     /locus_tag="OPV72_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HCR9914954.1"
                     /translation="MSQFFYIHPDNPQQRLINQAVDIVRKGGVIVYPTDSGYALGCKI
                     EDKGAMERICRIRHLPDGHNFTLMCRDLSELSTYSYVDNVAFRLMKNNTPGNYTFILK
                     GTKEVPRRLLQEKRKTIGLRVPSNPIALALLDTLGEPMLSTSLMLPGSDFTESDPEEI
                     KDRLEKQVDLIIHGGYLGQQPTTVIDLTNDSPVVLREGVGDVTPFL"
     gene            8652..9527
                     /gene="rluB"
                     /locus_tag="OPV72_002703"
     CDS             8652..9527
                     /gene="rluB"
                     /locus_tag="OPV72_002703"
                     /EC_number="5.4.99.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(2605) synthase RluB"
                     /protein_id="HCR9914955.1"
                     /translation="MSEKLQKVLARAGHGSRREIESIIEAGRVSVDGKIATLGDRVEV
                     TPGLKIRIDGHLISVKESAEQICRVLAYYKPEGELCTRNDPEGRPTVFDRLPKLRGAR
                     WIAVGRLDVNTCGLLLFTTDGELANRLMHPSREVEREYAVRVFGQVDESKLRDLSRGV
                     QLEDGPAAFKTIKFSGGEGINQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDI
                     PLPKGLPRGGWTELDLAQTNYLRGLVELPPETSSKVAVEKDRRRMKANQIRRAVKRHS
                     QIAGGRRSGGRNNNG"
     gene            complement(9614..10204)
                     /gene="cobO"
                     /locus_tag="OPV72_002704"
     CDS             complement(9614..10204)
                     /gene="cobO"
                     /locus_tag="OPV72_002704"
                     /EC_number="2.5.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cob(I)yrinic acid a,c-diamide
                     adenosyltransferase"
                     /protein_id="HCR9914956.1"
                     /translation="MSDERYQQRQQKVKDRVDARVAQAQEERGIIIVFTGNGKGKTTA
                     AFGTAARAVGHGKNVGVVQFIKGTWPNGERNLLEPHGVEFQVMATGFTWETQNREADT
                     AACMAVWQHGKRMLADPLLDMVVLDELTYMVAYDYLPLEEVISALNARPGHQTVIITG
                     RGCHRDILDFADTVSELRPVKHAFDAGVKAQMGIDY"
     gene            complement(10201..10962)
                     /locus_tag="OPV72_002705"
     CDS             complement(10201..10962)
                     /locus_tag="OPV72_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciK family oxidoreductase"
                     /protein_id="HCR9914957.1"
                     /translation="MHYQPKQDLLQNRIILVTGASDGIGREAALTYARYGATVILLGR
                     NEEKLRRVAQHIADEQHVQPQWFTLDLLTCTAEECRQVADRIAAHYPRLDGVLHNAGL
                     LGEIGPMSEQDPQIWQDVMQVNVNATFMLTQALLPLLLKSDAGSLVFTSSSVGRQGRA
                     NWGAYATSKFATEGMMQVLADEYQNRSLRVNCINPGGTRTSMRASAFPTEDPQKLKTP
                     ADIMPLYLWLMGDDSRRKTGMTFDAQPGRKPGIAQ"
     gene            11200..12246
                     /gene="sohB"
                     /locus_tag="OPV72_002706"
     CDS             11200..12246
                     /gene="sohB"
                     /locus_tag="OPV72_002706"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease SohB"
                     /protein_id="HCR9914958.1"
                     /translation="MELLSEYGLFLAKIVTVVVAIAVIVLLIVNATQRKRQRGELRVT
                     NLSEQYQEMKDDLAAALMDGHQQKLWHKAQKKKHKQEAKAAKAKAKLGDIATSDKPRV
                     WVIDFKSSMDAHEVNALREEVTAVLAVAKPGDRAVVRLESPGGVVHGYGLAASQLQRL
                     RDKNIPLTVTVDKVAASGGYMMACVAEKIIAAPFAIVGSIGVVAQIPNFNRFLKSKDI
                     DIELHTAGQYKRTLTLLGENTEEGRQKFREDLNETHHLFKEFVQRMRPALDIEQVATG
                     EHWYGQQALEKGLVDEINTSDEVILGLMEGREVLNVRYMQRKKLIDRVTGSAAESADR
                     LLLRWWQRGQKPLM"
     gene            complement(12288..12539)
                     /locus_tag="OPV72_002707"
     CDS             complement(12288..12539)
                     /locus_tag="OPV72_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciN family protein"
                     /protein_id="HCR9914959.1"
                     /translation="MHKETQPIDRETLLLEANKIIREHEDTMAGIVATGVTQRNGVLV
                     FSGDYFLDEQGLPTPKSTAVFNMFKHLAHVLSEKYHLVD"
     gene            12942..15539
                     /gene="topA"
                     /locus_tag="OPV72_002708"
     CDS             12942..15539
                     /gene="topA"
                     /locus_tag="OPV72_002708"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000513601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HCR9914960.1"
                     /translation="MGKALVIVESPAKAKTINKYLGNDYVVKSSVGHIRDLPTSGSAA
                     KKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWDAHYEVLPGKEKVVSELKQLAEK
                     ADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFEQPGELNIN
                     RVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEE
                     FWEIDANTTTPSGEALPLQVTHQNDKPFRPVNREQTLAAVSLLEKARYSVLEREDKPT
                     SSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNM
                     VRGYIGDNFGKKYLPDNPNQYASKENSQEAHEAIRPSDVAVMAESLKDMEADAQKLYQ
                     LIWRQFVACQMTPAQYDSTTLTVGAGEFRLKARGRILRFDGWTKVMPALRKGDEDRTL
                     PAVNKGDALTLLELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRG
                     YVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMEDSLDQVANHQAEWKAVLDN
                     FFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYAL
                     SPKERCKTTINLVPENEVLNVLEGDDAETNALRAKRRCQKCGTAMDSYLIDPKRKLHV
                     CGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNDECKNTR
                     KILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGIFLAANTFPKSRETRAPLVE
                     ELYRFRDRLPEKLRYLADAPQQDPEGNKTVVRFSRKTKQQYVAAEKDGKATGWSAFFV
                     DGKWVEGKK"
BASE COUNT         3628 a         4197 c         4478 g         3556 t
ORIGIN      
        1 tatctgcggc cctggaaacg ttaatgcatt gtttgttgac atttctttac ataaaggcgg
       61 gggaaattga cgtgaaaacg ctaaattttt cggcgtgatt aggagttttc ttagcaaaaa
      121 ttgacttcag actttttgaa agctggacgg ggaataacac caaaaagatt gatgatgtac
      181 gcctgaatcg tgattctggt ttggcgccaa cctctcatta agccgccagc gttatgctga
      241 cggcttaacc cgttatgcgc ggctggcggc tttcatcgct gagacaaagg acctgagctc
      301 cgccaacatc tgttcgggag acgcgaggtt tttctcgata atcttgacaa tggctgagcc
      361 ggagatagcg ccagccgccc cggcacgcac ggccgcagac acctgttccg gcgaggagat
      421 accgaagccc tgtaacgcag gcgcggcgtg gtactcttta agcttctcaa tgagatgatg
      481 caacggcaat gcgccacggt tttccgcgcc ggtgacgccc gaacgcgaaa gcaggtaggt
      541 ataaccgcgg ccgtaagatg cgacctggcg cagaagatcg tcatccgcat ttggcgggca
      601 gatgaagatc ggcgcgatat tatgccgtaa cgccgcctgg cggaaggggg ccgattcttc
      661 aaccgggaca tctgcgacca gcacggaatc tacgccaacc tgttcacaac gggcatagaa
      721 cgcatctatg ccgttattga acaccagatt cgcgtacatt agcaggccaa tcggaatggt
      781 cgggtgtttt tcacgaatca gcgccagcat ttcaaaacac tgagctggcg tgacgccagc
      841 ggcgaaggcg cgtaagttcg cattctggat ggtagggcca tcggccagag gatcggagaa
      901 gggaaccccc agctccagag cgtcggcgcc agcgtcaatc agtgtgtcaa taattttcag
      961 tgactgttca atgccagggt cgcccagggt cacgaagggg acaaaagcgc cttcccggcg
     1021 atcgttgagt tgggcaaata aattttcgta gcgttccatc agatttcccc tcgcgctttc
     1081 aggatatcgt gtacggtaaa gatgtcttta tctccgcggc cagagagatt gaccaccagc
     1141 agttgctctt tttccggctg ctcgcgcatc attttcagag cgtgcgccaa cgcgtgggag
     1201 gactccagcg ccgggataat tccctcatgg cggcacaacg ttttgaaggc ttccagcgcc
     1261 tcatcatcgg taatggagac ataatccgcg cgtccgatgc tgttcaggta cgcatgttgc
     1321 ggcccaacgg acgggaaatc gagtccggcg gaaatggaat aggactcttc aatttgcccg
     1381 tctgctgttt gcatcatcgg cgctttcatc ccgaaataga tgccaacgcg accatgttta
     1441 agcggcgcac catgctcgcc ggtttcaata ccgtgaccgc caggttcaac gcctattagc
     1501 ccgacgctgg tatcattaat aaaatccgca aacatcccga tagcgtttga gccgccaccg
     1561 acgcaagcga taacggcatc tggcagacgg ccctctttgt cgaggatttg cgctttcgtc
     1621 tcttcgccaa tcatgcgttg gaactcgcga acgatggtag gatagggatg cggtcctgcc
     1681 gccgtgccga gcatatagtg cgcggtttcg taactaccgg accagtcgcg cagcgcctcg
     1741 ttacaggcat cttttagcgt agcggagccg ctatgaaccg ggatgacctc agcgcccatc
     1801 agacgcatac ggaagacgtt cggcgactgg cgctcaacgt ctttggcacc catatagata
     1861 cggcatttca gacccagcag ggcgctggcg agcgcagagg cgacgccgtg ctgaccggcg
     1921 ccggtttcag cgataatctc gcttttaccc atccgtttgg ccagcagcgc ctgacccagt
     1981 acctgattgg ttttgtgtgc gccgccgtgc agtaaatctt cgcgctttaa atacaacgtg
     2041 gtacgcgtac cggcggtaat gttctggcat ttcgtcagcg cggtggggcg tcccgcgtag
     2101 ttttttagca gatcggcgaa ttgcgcctga aattcaggat ctttttgcgc gctgacgaag
     2161 gcctcttcaa gctggttcag cgcaggcatc aggatctgcg gcacatacat gccgccgaat
     2221 tcaccaaagt aggggttgag aagtgttgtc atgttttttc cttaatatgc gcgcagtgtc
     2281 tgaaaaaccg aggccagaag acgagcatct ttgatgcccg gctgtgactc cacacctgaa
     2341 ttaaaatcga gaccggcaca gccgacttgc gccgcctgga cgcagttatc ggccgccagc
     2401 ccgcccgcca gtaacacatc atccagcggt tgcccctgta gcagtgacca gtcgaagcgc
     2461 tgcccgctgc cgccttgccc attgtcgaaa atgtatttat cgacatggtg ataatcgcgt
     2521 gcgggaaggg cattgctaac gctcagcgcc ttccagattt gcacattgcg cggcaacgcc
     2581 tcgcgcagcg cgttgacata cgcctggtct tcgctgccat gtagctgtac ggcagaaagc
     2641 gacaggacgg cggctttctg gcaaacatcg gcgatatcag cgttcttgaa aacgccgaca
     2701 tactgcaatg gcgcgccgct tatcacttct cgcgcctgct caacgctaac cgcgcgcgga
     2761 gatgagggca caaaaatcaa cccgccatat attgcgccag cgtcacaggc cgctttagcg
     2821 tcctgggcgc gggtcaggcc gcagacttta ttttcgccaa gcagcacgcg acggacggcg
     2881 gcgttaagat cgtcatgcgc cattaacgcg gagccaatta aaaaaccgtt ggcgaagtgg
     2941 ctcagttcgc gtacctgacc ataggtgtta atcccggact cgctgatgac agtcacgccg
     3001 tggcccagtt ttggcgccag ctggcgggtg cgattcaaat caatcgacag atcgcgcaga
     3061 tcgcgattgt tgatacctac cacttttgcg cctaacgcta tcgcgcgctc ccgttcttcg
     3121 tcattactga tctccgtgag cacgcccatt ttcagactgt gcgcgacggc ggagagttgg
     3181 cgatactgtt cgtcatccag aaccgagagc atcagtaaac aggcatcggc ctgatagtaa
     3241 cgggcaaggt agatctgata gggatcgata ataaaatcct tacacagaat cggctgcggc
     3301 gcgctttggc taacgaccgg cagaaaatcg aagctcccct gaaaatattt ttcgtcggtg
     3361 agcaccgaga tcgccgaggc gtaatgttga taaatactgg caatacgcgc cggatcgaaa
     3421 tcgtcgcgaa tcacgccttt tgatggcgat gctttcttac actccagaat aaaggcggta
     3481 cgcgcgccct ggagcgcatc ataaaaatgg cgtgtacttg gctggatctc attttgaaaa
     3541 ctggccagcg gctgttgctg tttgcgggct tctacacaaa tcgccttgtc tgcgacgatt
     3601 ttcgctaaaa cggtttgcat tatttaccct cttgccgcca gtgcggtgac tctgtcatat
     3661 gcggtgccgt tgcgcagaac atcaagcacg gtttgcgcgt tggccttgag atcttcctga
     3721 ccatgcagac gcatcagcat cgccacgttg gcggcgacgg cggcctcatg cgcggcatcg
     3781 cctttacctt gtaataaccg cgtcagaatg tcacggtttt cttccggcgt gccgccagcc
     3841 aactgatcct gatggtaagg cgtcaggcca aaatcctccg ccgtaagttg atagctttta
     3901 atttcgccgt catgcagctc cgcgacaatc gtcggcgcat ggagcgaaac ctcatccatg
     3961 ccgccgctat gtaccaccgc cgcgcgctga tagcccagta cccgtaaggt ttccgcaatc
     4021 ggcagcacca gttccgggct atagacgcca atcaatgcca gcggcggatg cgctgggttg
     4081 atcagcgggc cgagtacgtt gaacagggtt cgcgttttta actgttggcg aaccggcatc
     4141 gcgtgacgga atccggtgtg atatttcggc gcgaacagga aacagacgcc cagttcatct
     4201 aacgcctgac gtgatttatc ggcgttcata tccagattaa taccgaacgc cgccaacaga
     4261 tcggatgacc ccgatttgct ggatacgctg cggttgccgt gtttcgccac tttcagtcca
     4321 caggccgccg cgacaaaggc gctggcggta gagatattga tactgttact gccatcgccg
     4381 ccggtaccaa cgatatccgc aaacagatag tccgggcgcg ggaacggggc ggcattttcc
     4441 agcaacgcag tggcggcgcc ggcaatttca ttgggatgct cgccgcgaat tttcatgctc
     4501 accagcgcgg cggcgagctg ttcaggctta agttcgccgc ggacgaccgc cgaaaacaac
     4561 tgatggctct cttgttgcgt cagagtttgc gcctgataga gtttctccag aattggctgt
     4621 agggtgttgg tcggttccag cttttgctgc gcccaggcta atgtttgctc cagtagacgc
     4681 gcgccctgtg tcgtcaggat ggactcagga tgaaattgaa aaccgcaaac gcgatccgca
     4741 tcatgacgta ccgccatcac catgccgttg aaatgggcgt taatggttag cccggcagga
     4801 acattactgc cgaccagcga atgataacgc gcgaccggta gcggattcgc cagaccggcg
     4861 aacatcgcct gaccgtcatg ttcaatgctg gaggctttgc catgcaggat ttctcccgcc
     4921 tgaccgacat aaccgccgta agcttcgaca atcgcctgat gccccagaca aatgccgatg
     4981 atcggtaact tgccgcgtag tcgggtcagc agctccggca tacagcctgc ctcgctggga
     5041 atgcccggac cgggggagag cattagcacc ggatttttca ttgtcgccag gcgatcgata
     5101 agcgtctgcg ccggaatatg gttacggtaa atcaccacgt tatgaccgtt ggtccgtagc
     5161 tgatctgcca ggttccaggt aaacgagtcg atgttatcga gcagcagaat atcagccatc
     5221 agaaggtctc ctgtgcatga tgcgcggtgg cgatagcacg caatacggcg cgcgctttat
     5281 tacgggtttc atcggcttca gactgcggaa cagagtccag cacgattccg gcgcccgcct
     5341 gtacggtggc gataccgttc tccaccagcg cggagcggat aacaatacag gtgtccagat
     5401 cgccgtgggc ggtgaagtaa ccgaccgcgc cgccatagct gccgcggcgc tgtccttccg
     5461 catcggcaat caactgcatg gcgcgtactt tcggcgcgcc gctcagggtg cccatgttca
     5521 tgcaggcgcg ataggcgtgc agcgcgtcga gatcgtgacg cagttcgccc actacccggg
     5581 aaaccagatg catcacgtac gaatagcggt caactttggt cagatcggca acgtagcgac
     5641 tgcccggcgt acagatgcgc gccaggtcat tgcgcgccag atcgaccagc atcagatgtt
     5701 cggaaagctc tttctggtcg gtacgcatgt ccagctcaat acggctgtcg agatctctgt
     5761 ccagcgtacc atcggcgcgg cgaccgcgtg gacgggtacc cgcgatgggg taaatctcaa
     5821 tctgacggct ggcggcgtca tatttcagcg agctttccgg cgacgcgccg aaaagcgtga
     5881 aatcattatc ctgcataaag aacatatacg ggctggggtt gctctttttc agcacgtagt
     5941 aggcagccaa cggcgacggg cagggcagtg aaaagcggcg cgacggcacc acctgaaata
     6001 tctcgcccgc gcggatggct ttttgcaact ggcgtaccac cgcgccgaac gcgtcatcgc
     6061 tctgattgca ttcacagcgc atgtccggca ccggcgtcac cggcaacggc ggcgcaggct
     6121 gggttaactg ttggctaagg tacgccaggc gggcgttgag gcgctgtttt tccaggtcgc
     6181 tggcggtgaa cagactggcc tgaatacggg tgcttttttt ctgatgatct atcaccatca
     6241 gcgtttccgc taaataaaag cagtagtccg ggcagttatt gccagcctca aggtgtggca
     6301 gcgcttcaaa gccagcgacc aggtcgtagg caaacagacc gccgaaaaac atagcctccc
     6361 gctcttgcgt cggtatgttc accactccct gtaacaggcg gaacgcatca aataccgaca
     6421 gagagcataa acgggcgtct tcatctaata atgggctgac gggcggaaag cgtagaatgc
     6481 gaccggcagg caggacttcg ttctccacgc cagcgggcag ggcggtatcc agtagcggca
     6541 ataacgaggc gccattatca gataacgcct gaatagtgac agtgtcacct aaagcggtaa
     6601 tgcgcagcgc gctatctacc agcagcaggc tttttaaatc gtctttactg tcgatatccg
     6661 cggattccag cagcagcgtt gccgggcgat cgccgcagac ctggtgaaaa agcgccgttg
     6721 ggttttcccg gtaggcggca tcgcaggtca atagttcgag cgtgggtttt ggtgtttgca
     6781 tggttattct cattattttg ttcaaaaaaa agcccgctta acaggcgggc cgggtatcgt
     6841 ttggctgatt acagctgttc atacaccgcc cgctatcagg aagtgcgcca ccaaccgtgt
     6901 aatgcaaatg tcgctgccat tttagatacc ctcttcatgt gaactttcgt actagttaac
     6961 tggttcaatg gaataatgtc aacacctatt tcagtatatt tgccggaacc gttatgatgt
     7021 acatgacata cctttatctc tatgggagcc gccttgagcg acacgaatta cgcagtgatt
     7081 tacgatctgc acagtcatac cacggcgtcc gatggactgt tgacgccaga aacattagta
     7141 caccgtgcgg tagagatgcg agtcggcacg ctggcgatta ccgatcatga caccacagct
     7201 gcgattcctg cggcaagaga agaaatttca cgttgcgggc tggccctgaa tctgattccc
     7261 ggcgtggaga tttcaacggt ctgggagaat catgagattc acattgtggg tctgaatatt
     7321 gatattgcgc acccggcaat gcgcgatttt ctagcgcagc agacacatcg gcgtcaggcg
     7381 cgtggtcggc tcattgcgga gcgtctggaa aaagcccata ttcccggcgc gtgggaaggg
     7441 gcattgagac tggccaatgg cggcgcggtg acgcgcggcc acttcgcccg ctttctggtg
     7501 gagtgcggca aagccacgac catggcggag gtttttaaaa aatatctcgc gcgtgggaaa
     7561 accggttacg ttccgccgca gtggtgtaca atagaacaag ctattgatgt cattcatcat
     7621 tctggcggta aggcggtgtt ggcccacccg ggacgctacg accttagcgc taagtggctg
     7681 aaaagattag tggcgcattt tgccgaccat cacggcgacg cgatggaagt ggcgcagtgc
     7741 caacaatcac ccaatgaacg cacccaactg gcgacgcttg cgcgtcagca tcatttatgg
     7801 gcatcgcttg gatctgattt ccatcagccc tgcccgtgga ttgagttggg gcgtaaactc
     7861 tggctgcccg ctggcgttga aggcgtatgg caggcatggg aacagccgca aatatcacag
     7921 tgagggaagt atgagccagt ttttttatat ccatccggat aacccacagc aacggctgat
     7981 taatcaggcc gtcgacattg tgcgtaaagg cggtgttatt gtttatccaa ccgattccgg
     8041 ctatgccctt ggttgtaaaa ttgaagacaa aggcgcaatg gagcgcattt gccgcatccg
     8101 tcatctgccg gacggccaca acttcacgct gatgtgccgc gatttgtccg agttgtcgac
     8161 ctactcctac gtcgacaacg tggcatttcg tctgatgaaa aacaatacgc cgggtaatta
     8221 cacctttatc ctgaagggga caaaagaggt gccgcgccgt ctgttgcagg aaaagcgtaa
     8281 aactatcggc ctgcgcgtac cgtcaaaccc gattgcgctg gcgttattgg atacgctggg
     8341 cgaaccgatg ctctcgacgt cgttgatgct gcctggcagc gattttaccg agtcggaccc
     8401 ggaggagatt aaagatcggc tggagaagca ggtggatctg atcatccacg gtggttacct
     8461 cggtcaacag cctaccacgg taatcgattt gaccaatgac tccccggtgg tgctgcgcga
     8521 aggcgtcggc gacgttacac ctttcttata agggcgtaag cctgtatact acgcggcctt
     8581 aaaatggcgc ggcaacgcgc cgttcattct cctgttcgac gcctgtgaag gcgacacctg
     8641 aaggaagctc tatgagcgaa aagttacaaa aagtgctggc gcgcgctggc cacggctctc
     8701 gccgtgaaat cgaatccatt attgaagcgg gacgtgtcag cgttgacggt aaaatcgcca
     8761 cgcttggcga tcgtgttgaa gtcactcccg gtttgaaaat ccgtatcgac ggtcacctga
     8821 tttcggtgaa agagtcggcg gaacaaattt gccgcgttct ggcctattac aaaccagaag
     8881 gtgaactgtg tacccgcaat gaccctgaag ggcggccaac cgtttttgat cgcttaccga
     8941 aactgcgcgg cgcgcggtgg attgcggtag gacgtctgga tgtcaacacc tgcgggctat
     9001 tgttgtttac caccgacggt gaactggcga accgcctgat gcatcctagt cgcgaagttg
     9061 aacgtgaata tgccgtgcgc gtgttcggtc aggtggatga atcgaaactg cgtgatttaa
     9121 gccgtggcgt acagttggaa gatggtccgg cggcatttaa gaccattaaa ttcagcggcg
     9181 gcgaaggcat taaccagtgg tataacgtga cgctgacgga agggcgcaac cgcgaagttc
     9241 gccgactgtg ggaagcggta ggcgttcagg tcagccgtct gatccgcgtt cgttacggcg
     9301 atatcccgct gccgaaaggc ctgccgcgcg gcggctggac tgagctcgac ctcgcgcaaa
     9361 cgaactatct gcgtggtctg gtagagctcc cgccggaaac ctcgtcgaag gttgccgtcg
     9421 aaaaagaccg tcgtcgtatg aaagcgaacc agatccgtcg ggcggtaaaa cgccacagcc
     9481 agatagctgg cggacgccgc tccggtgggc gtaataacaa cgggtaatct ctaccgtggt
     9541 ttataggccg agagtcatca gacaagaggg tttgtgccgg atggcggcgc aaacgcctta
     9601 atccggccta cggttaataa tcaattccca tctgggcttt tacgcccgcg tcgaaagcat
     9661 gtttaaccgg acgcagttcg ctgacggtat ccgcaaaatc aagaatatcc cggtgacagc
     9721 cgcgacctgt aataatcacc gtctggtgac cagggcgcgc gtttagcgcg cttatgacct
     9781 cttccagcgg taaatagtca tacgccacca tataggtcag ctcatccagc actaccatat
     9841 caagcagcgg atcggccagc attcgtttcc catgctgcca aacggccata catgctgcgg
     9901 tgtctgcctc gcgattttgc gtctcccagg taaatcccgt tgccatcacc tgaaattcga
     9961 cgccatgcgg ttccagcaga ttacgctcgc cgttgggcca ggtgccttta ataaattgca
    10021 ccacgcctac gtttttaccg tgtcctacgg cgcgggcggc agttccgaaa gccgccgtgg
    10081 ttttgccctt accattgcca gtaaacacga taataatacc gcgctcttcc tgtgcctggg
    10141 cgacacgggc gtcaacccga tcttttacct tctgctggcg ctgctgataa cgttcatcac
    10201 tcattgggcg attcctggtt tacggcccgg ttgggcgtca aaggtcatac cggttttacg
    10261 gcgactgtcg tcgcccataa gccacaggta aagcggcata atatcggcag gcgtttttaa
    10321 tttctgtgga tcttccgtcg gaaaggcgct ggcgcgcata ctggtgcgcg tgccgcccgg
    10381 gttaatgcag ttaacacgca gagaacggtt ctggtattcg tccgccagca cctgcatcat
    10441 tccttcagta gcaaacttcg aggtggcata ggcgccccag ttggcgcgtc cctgacggcc
    10501 aacgcttgat gacgtaaaga ccagcgagcc ggcatcggac ttcaataata acggtaacag
    10561 cgcctgggtg agcataaagg tggcgttaac gtttacctgc atgacatcct gccagatctg
    10621 cggatcttgt tcgctcattg ggccgatttc ccccagtaac ccggcattgt gcaggacgcc
    10681 atccaggcgg ggatagtgcg cggcgatgcg gtcggccact tgccggcact cttcagcggt
    10741 gcaggtcagc agatcgagcg taaaccactg tggttgaaca tgttgctcgt cagcaatgtg
    10801 ctgcgcgacc cgacgcagtt tctcttcgtt gcgtcccagc agaatcaccg ttgcgccgta
    10861 acgcgcatac gtgagcgcgg cttcccgccc aatgccatcg ctggcaccag tgaccagaat
    10921 aatgcggttt tgcaatagat cttgtttcgg ttggtaatgc atggctactc ctcaacggtg
    10981 tggtgcaccg tcctgccagg ttgtcttatc ttcgcgttaa cttttcgggt ttatgcctga
    11041 aagcgccttt tttttcaatc agacaggggc gataacgccg taaaatgaac gtcttgtcat
    11101 actttttctt cctcaacagg catacggatg aagagagact gacttcgatg cctgttgtac
    11161 actgagcgca agtcgcgtta tttaatcaag gtgggagtcg tggaattgtt gtctgaatat
    11221 ggcttatttt tggcaaaaat cgtcaccgtt gtggtggcca ttgccgtcat tgtgctgctg
    11281 atcgtgaatg ctacgcaacg caaacgtcag cgcggcgagc tgcgcgtgac caatttgagt
    11341 gagcagtatc aggagatgaa ggatgacctt gctgcggcgt tgatggatgg ccatcagcaa
    11401 aaactgtggc ataaagcgca gaaaaaaaag cataagcagg aggcgaaagc cgccaaagcg
    11461 aaagcgaagc tgggggacat tgcgacatcg gacaaaccgc gcgtatgggt gatagatttc
    11521 aaaagcagta tggacgctca cgaagttaat gcgttacgcg aagaggtcac ggcggtgctg
    11581 gcagtggcga aacccggcga tcgggcggtt gtgcgtctgg aaagccccgg tggcgttgtg
    11641 cacggctatg gcctggcggc atcgcaattg cagcgcctgc gcgataaaaa tattccgctg
    11701 accgtgacgg tggataaagt cgcggcaagc ggaggctaca tgatggcctg cgtggcggaa
    11761 aaaattatcg cggcgccgtt cgctattgtg gggtcaattg gtgttgtcgc gcaaatcccg
    11821 aactttaacc gctttctcaa aagtaaagac attgatattg aactgcatac cgcagggcag
    11881 tacaaacgta ccctgacttt gttaggcgag aatacggaag aagggcggca gaagtttcgt
    11941 gaagatctca acgaaacgca ccatctgttc aaagagtttg tgcagcggat gcgtccggct
    12001 ctggacattg aacaggtcgc cacgggcgaa cactggtacg gtcagcaggc gctggagaag
    12061 ggactggttg atgagattaa caccagcgat gaggttatcc tcggcctgat ggaagggcgc
    12121 gaggtgctga atgtgcgcta tatgcagcgt aaaaaactga tcgatcgtgt taccggcagc
    12181 gcggcggaaa gcgcggatcg gctgctgctg cgctggtggc agcgtggaca aaagccgttg
    12241 atgtaaaccg ctattgccgg atggcattca gcgccatccg gcatggatta atcaaccagg
    12301 tgatacttct cagacagcac atgcgccagg tgtttaaaca tgttaaacac cgcggtgctt
    12361 ttaggggtcg gtaacccttg ctcgtctaaa aagtaatcgc cgctgaaaac cagcacgcca
    12421 tttctctgcg ttacgccggt ggcgacaata cctgccatcg tgtcttcatg ttcccgaata
    12481 attttgttgg cttcaagcaa cagtgtttcg cgatcgatag gttgcgtctc tttatgcatt
    12541 ttttactcct taaacaagga gattagtcta cgctgagcac ttctgatggg caaatattct
    12601 cacaggaaat tgatggattt gtcatgttgc gttcactggc aagatttgtt tttgcatgct
    12661 aataaagttg cgtatcgaat tttatcaggt acagtgtgac gctttcgtca atctggcaac
    12721 agaattgctt gacattcgac caaaattccg tcgtgctata gcgcgtgtgt gcaaaaaagc
    12781 ctgttaactc agtcacctga gggttacatt tcgtacacaa agccagtaca aggggttgat
    12841 atccgcagac gcagagacca tatatcgttg tctcgtcgcc agtggaaggt gaatcaacgt
    12901 gcgacgcatt cctggaagaa tcaacttagg taaaggtgaa tatgggtaaa gctcttgtca
    12961 tcgttgagtc cccggcaaaa gccaaaacga tcaacaagta tctgggtaat gactacgtgg
    13021 tgaaatccag cgtgggtcat atccgtgatt tgccgaccag tggctcagca gctaaaaaga
    13081 gcgccgactc tacctccacc aaaacggcta aaaagcccaa aaaggatgaa cgtggcgctc
    13141 tcgtcaaccg tatgggggtt gacccgtggc acaactggga tgcgcactat gaagtgctgc
    13201 ccggtaaaga gaaggtcgtc tctgaactga aacagttggc ggaaaaagcc gaccacatct
    13261 atctcgcaac cgaccttgac cgcgaagggg aagccattgc atggcacctg cgggaagtga
    13321 tcggcggcga tgacgcgcgc tacagtcgcg tagtctttaa cgaaataacc aaaaatgcca
    13381 ttcgccaggc gtttgaacag ccgggcgagc tgaacattaa cagggtcaac gcccagcaag
    13441 cgcgccgctt tatggaccgc gtggtaggct atatggtctc gccgctgctg tggaaaaaga
    13501 tcgcccgtgg tttgtcggca ggtcgcgttc agtctgtcgc ggtccgtctg gtcgttgagc
    13561 gcgagcgcga gattaaagcg tttgttccgg aagagttctg ggagattgac gctaatacga
    13621 cgacgccgtc tggcgaggca ctaccgctac aggtcacgca tcagaacgac aagccattcc
    13681 ggccggtaaa tcgcgagcag acgcttgccg ccgtcagctt gttggaaaaa gcgcgctata
    13741 gcgtactgga gcgtgaagac aaaccgacca gcagcaaacc tggcgcgccg tttatcacct
    13801 ccacgctaca acaggcggcc agcacccggc tgggctttgg cgtgaagaaa accatgatga
    13861 tggcgcagcg tctgtatgag gcgggctaca tcacctatat gcgtaccgac tccaccaacc
    13921 tgagtcagga tgcggtcaac atggtgcgcg gctatattgg cgataatttc ggcaagaaat
    13981 acctgccgga taacccgaac caatacgcca gcaaagaaaa ctctcaggaa gcgcacgaag
    14041 cgatccgtcc ttccgacgtt gctgtcatgg cggagtcgct gaaagacatg gaggctgacg
    14101 cgcagaagtt gtatcagcta atttggcgtc agtttgtcgc ctgtcagatg acgccagcac
    14161 aatatgactc cactacgctt accgttggcg caggcgaatt ccgtctgaaa gcgcgtgggc
    14221 gtattttgcg ctttgacggc tggacaaaag tgatgccggc gctgcgtaaa ggcgatgaag
    14281 atcgcacatt gcctgccgtg aataagggcg atgcgctgac gctacttgaa ttgacgcctg
    14341 ctcagcactt tactaaaccg ccagcccgtt tcagcgaggc ttctctggtt aaagagcttg
    14401 agaagcgcgg tattggtcgt ccgtctacct atgcgtcgat tatctcgacc attcaggatc
    14461 gcggctatgt tcgcgttgaa aaccgtcgct tctatgcgga aaaaatgggt gaaatcgtca
    14521 ccgaccggct ggaagaaaac ttccgcgaat tgatgaacta cgattttacc gcgcagatgg
    14581 aagatagtct ggatcaggtt gcgaatcacc aggccgagtg gaaagcggtg ctggataact
    14641 tcttcagcga ttttactcag cagctcgata aagccgagaa agatccggaa gaagggggga
    14701 tgcgtcctaa ccagatggtg ctgaccagca tcgactgtcc aacctgtggc cgtaaaatgg
    14761 gaattcgtac tgccagtacg ggggttttcc ttggttgttc aggttatgcg ctttcgccga
    14821 aagagcgttg taaaacgacc attaacctgg tgccggaaaa tgaagttctg aacgtgctgg
    14881 aaggcgacga cgccgaaacc aacgccctgc gcgccaaacg tcgctgtcag aagtgcggta
    14941 cggcgatgga cagctatctg atcgatccga agcgtaaatt gcatgtgtgt ggtaataacc
    15001 cgacctgtga cggctacgag attgaagaag gcgagttccg catcaaaggg tatgacggcc
    15061 cgatcgttga gtgtgagaaa tgtggttccg aaatgcacct gaaaatgggg cgttttggta
    15121 agtacatggc ctgtactaac gacgaatgta aaaatacccg taagatcttg cgtaacggcg
    15181 aagttgcgcc gccgaaggaa gatcctgttc cattgccgga actgccgtgt gaaaaatcgg
    15241 acgcgtactt tgtgctgcgc gatggcgccg cagggatatt cctggcggcc aatacgttcc
    15301 cgaaatcacg tgaaacgcgc gcgccattag tcgaggagct ttaccggttc cgcgatcgcc
    15361 tgccggaaaa actgcgttat ctggcggatg cgccgcagca ggatccagaa ggcaataaaa
    15421 ccgttgttcg ctttagccgc aaaacaaaac agcagtacgt tgcggcggaa aaagacggga
    15481 aggcgacggg atggtcagcg ttcttcgtcg acggcaagtg ggttgaaggt aagaaataac
    15541 cccggcctgt cgccactgta gtcaagcggg ccgcgtaagc ggcccttttt tatatcccct
    15601 tcatatttca agtggcttat gtgttggcta cggattactc ggcccatcta tgggcctcgc
    15661 cctgacgggc cgtcgcacgc gacgttcaaa tctgctcccg gctgatttgt cgctcacccc
    15721 agtcccctgg ttatctatgc tccagggaac tcactcgctt gttgccttta atcactcgaa
    15781 ttattttggg tatagcgggc ttattatttt atcgcgctgg ctatacagtt cagatataaa
    15841 tgatatagtg gttatagtt
//
LOCUS       DAJVBX010000103        15595 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.103, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000103 DAJVBX010000000
VERSION     DAJVBX010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 15595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15595
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.103"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..771)
                     /gene="sifA"
                     /locus_tag="OPV72_002709"
     CDS             complement(<1..771)
                     /gene="sifA"
                     /locus_tag="OPV72_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system effector SifA"
                     /protein_id="HCR9914961.1"
                     /translation="MPITIGNGFLKSEILTNSPRNTKEAWWKVLWKKIKDFFFSTGKA
                     KADRCLHEMLFADRTPTRERFTEIFFELKELACASQRDRFQVHNPHENDDTIILRIMD
                     QNEENELLRITQNTDTFSCEVMGNAYFLIKDRPDILKPHPQMTAMINRRYSEIVDYPL
                     PSTLCLNPAGAPTLSVPLDNIEGYLYSEWRKGNLDEWKTQEKATYLAAKIQSGIEKTT
                     RILQHANISESTQQNAFLETMTMCGLKQLEIPPPHTHIP"
     gene            complement(1100..1963)
                     /gene="potB"
                     /locus_tag="OPV72_002710"
     CDS             complement(1100..1963)
                     /gene="potB"
                     /locus_tag="OPV72_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter permease
                     PotB"
                     /protein_id="HCR9914962.1"
                     /translation="MKNTSKFQNVVIVTIVGWLVLFVFLPNLMIIGTSFLTRDDASFV
                     KMVFTLDNYARLLDPLYFEVLLHSLNMALIATLSCLVLGYPFAWFLAKLPEKIRPLLL
                     FLLIVPFWTNSLIRIYGLKIFLSTKGYLNEFLLWLGVIDTPIRIMFTPSAVIIGLVYI
                     LLPFMVMPLYSSIEKLDKPLLEAARDLGASKMQTFIRIIIPLTMPGIVAGCLLVMLPA
                     MGLFYVSDLMGGAKNLLIGNVIKVQFLNIRDWPFGAATSITLTIVMGLMLLIYWRASR
                     LLNKKVSDISD"
     gene            complement(1947..3083)
                     /gene="potA"
                     /locus_tag="OPV72_002711"
     CDS             complement(1947..3083)
                     /gene="potA"
                     /locus_tag="OPV72_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     ATP-binding protein PotA"
                     /protein_id="HCR9914963.1"
                     /translation="MGQSKKLNKQPRSLSPLVLLSGISKSFDGKEVISQLDLTINNGE
                     FLTLLGPSGCGKTTVLRLIAGLETVDAGHIMLDNQDITHVPAENRYVNTVFQSYALFP
                     HMTVFENVAFGLRMQKTPAAEIAPRVTDALRMVQLEEFAQRKPHQLSGGQQQRVAIAR
                     AVVNKPRLLLLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRI
                     VVMRNGVIEQDGTPREIYEEPKSLFVAGFIGEINRFDATVIERLDEQRVRASVEGREC
                     NIYVNFAVELGQKLNVLLRPEDLRVEEINDDNHIEGLIGYVRERNYKGMTLESVVELE
                     NGKMVMVSEFFNEDDPDFDHSLDQKMAISWVESWEVVLADEEHK"
     gene            3334..4563
                     /gene="pepT"
                     /locus_tag="OPV72_002712"
     CDS             3334..4563
                     /gene="pepT"
                     /locus_tag="OPV72_002712"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HCR9914964.1"
                     /translation="MDKLLERFLHYVSLDTQSKSGVRQVPSTEGQWKLLRLLKQQLEE
                     MGLVNITLSEKGTLMATLPANVEGDIPAIGFISHVDTSPDFSGKNVNPQIVENYRGGD
                     IALGIGDEVLSPVMFPVLHQLLGQTLITTDGKTLLGADDKAGVAEIMTALAVLKGNPI
                     PHGEIKVAFTPDEEVGKGAKHFDVEEFGAQWAYTVDGGGVGELEFENFNAASVNIKIV
                     GNNVHPGTAKGVMVNALSLAARIHAEVPADEAPETTEGYEGFYHLASMKGTVDRAEMH
                     YIIRDFDRKQFEARKRKMMEIAKKVGKGLHPDCYIELVIEDSYYNMREKVVEHPHILD
                     IAQQAMRDCHITPEMKPIRGGTDGAQLSFMGLPCPNLFTGGYNYHGKHEFVTLEGMEK
                     AVQVIVRIAELTGKRGQ"
     gene            4567..5901
                     /locus_tag="OPV72_002713"
     CDS             4567..5901
                     /locus_tag="OPV72_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914965.1"
                     /translation="MLHIVVKRFIIYGGIFSAINFSAWSAEYTPSWSQRQQQSAACFM
                     TGDETCMTFIDDAVRLASRQYGKRSIQLVRSLLLQSDIYQWLGKPELTPQMLLRARAI
                     MKTFPAGTYPGDRADMFEHLAAFYVYGDDRHIEYSPTEQWRYEIKVDYRQRIAWQEQA
                     LTWRLKDKKTSTEALVYTLNRMRDAYSDALEERDVECDSARKAYYLAKIDAAERQWLS
                     VILRDKTWDNRERVASFLQQKADIAYNAGHISEAINALSQALKIEQTLYGTEFGEMTV
                     DSNNLAGFYAQGHHYKEAKDLYLKLIAYYQSRLTPMATVISRLRFYLPENIDLDSTSP
                     YLPLLEEYKRRQSDVSMVLYGISLLYKNNQQLEQAKDFAERAFTLDAVAYPAKMQYER
                     LQQLANIAEGLGDNAQARRYRQMSFRHRMAHSIYPGDPQYNDFAKPGGDRCG"
     gene            complement(5941..7062)
                     /locus_tag="OPV72_002714"
     CDS             complement(5941..7062)
                     /locus_tag="OPV72_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HCR9914966.1"
                     /translation="MEYQLTLNWPDFLERHWQKRPVVLKRGFTNFIDPLSPDELAGLA
                     MESEIDSRLVSHQDGKWQVSHGPFESYDHLGESNWSLLVQAVNHWHEPTAALMRPFRA
                     LPDWRIDDLMISFSVPGGGVGPHLDQYDVFIIQGTGRRRWRVGEKLQMRQHCPHPDLL
                     QVDPFEAIIDEELEPGDILYIPPGFPHEGYALENAMNYSVGFRAPNSRELISGFADYV
                     LQRDLGNTYYSDPDMPSRKHPADILPQEMDKLRNMMLDLINQPAHFQQWLGEFISQSR
                     HELDIAPPEPPYQPDEIYDALKQGEALVRLGGLRVLRIGDEVYANGEKIDSPHRPALE
                     ALTSHIVLTAENFGDALEDPSFLAMLAALVNSGYWFFEG"
     gene            complement(7143..8606)
                     /gene="phoQ"
                     /locus_tag="OPV72_002715"
     CDS             complement(7143..8606)
                     /gene="phoQ"
                     /locus_tag="OPV72_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     PhoQ"
                     /protein_id="HCR9914967.1"
                     /translation="MNKFARHFLPLSLRVRFLLATAGVVLVLSLAYGIVALVGYSVSF
                     DKTTFRLLRGESNLFYTLAKWENNKISVELPENLDMQSPTMTLIYDETGKLLWTQRNI
                     PWLIKSIQPEWLKTNGFHEIETNVDATSTLLSEDHSAQEKLKEVREDDDDAEMTHSVA
                     VNIYPATTRMPQLTIVVVDTIPIELKRSYMVWSWFVYVLAANLLLVIPLLWIAAWWSL
                     RPIEALAREVRELEDHHREMLNPETTRELTSLVRNLNQLLKSERERYNKYRTTLTDLT
                     HSLKTPLAVLQSTLRSLRNEKMSVSKAEPVMLEQISRISQQIGYYLHRASMRGSGVLL
                     SRELHPVAPLLDNLISALNKVYQRKGVNISMDISPEISFVGEQNDFVEVMGNVLDNAC
                     KYCLEFVEISARQTDDHLHIFVEDDGPGIPHSKRSLVFDRGQRADTLRPGQGVGLAVA
                     REITEQYAGQIIASDSLLGGARMEVVFGRQHPTQKEE"
     gene            complement(8606..9277)
                     /gene="phoP"
                     /locus_tag="OPV72_002716"
     CDS             complement(8606..9277)
                     /gene="phoP"
                     /locus_tag="OPV72_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator PhoP"
                     /protein_id="HCR9914968.1"
                     /translation="MRVLVVEDNALLRHHLKVQLQDSGHQVDAAEDAREADYYLNEHL
                     PDIAIVDLGLPDEDGLSLIRRWRSSDVSLPVLVLTAREGWQDKVEVLSSGADDYVTKP
                     FHIEEVMARMQALMRRNSGLASQVINISPFQVDLSRRELSVNEEVIKLTAFEYTIMET
                     LIRNNGKVVSKDSLMLQLYPDAELRESHTIDVLMGRLRKKIQAQYPHDVITTVRGQGY
                     LFELR"
     gene            complement(9404..10774)
                     /gene="purB"
                     /locus_tag="OPV72_002717"
     CDS             complement(9404..10774)
                     /gene="purB"
                     /locus_tag="OPV72_002717"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HCR9914969.1"
                     /translation="MELSSLTAVSPVDGRYGDKVSALRGIFSEYGLLKFRVQVEVRWL
                     QKLAAHAAIKEVPAFAADANGYLDTLVANFNEEDAARIKTIERTTNHDVKAVEYFLKE
                     KAAAIPALHDVSEFIHFACTSEDINNLSHALMLKTARDEVILPYWRQVINAVKDLATQ
                     YRDIPLLSRTHGQPATPSTLGKEMANVAYRMERQFRQLNQVEILGKINGAVGNYNAHI
                     AAYPEVDWHQFSEEFVTSLGIQWNPYTTQIEPHDYIAELFDCIARFNTILIDFDRDVW
                     GYIALNHFKQKTIAGEIGSSTMPHKVNPIDFENSEGNLGLSNAVLHHLANKLPVSRWQ
                     RDLTDSTVLRNLGVGIGYALIAYQSTLKGVSKLEVNRDHLLDELDHNWEVLAEPIQTV
                     MRRYGIEKPYEKLKELTRGKRVDAEGMKQLIDSLALPEAEKTRLKAMTPANYIGRAVN
                     LVDELK"
     gene            complement(10778..11419)
                     /gene="hflD"
                     /locus_tag="OPV72_002718"
     CDS             complement(10778..11419)
                     /gene="hflD"
                     /locus_tag="OPV72_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high frequency lysogenization protein HflD"
                     /protein_id="HCR9914970.1"
                     /translation="MAKNYYDITLALSGICQSARLVQQLAHQGHCDADALHVSLNSVI
                     DMNPSSTLGVFGGSEANLRLGLETLLGVLNASSRQGLNAELTRYTLSLMVLERKLSSA
                     KGALNTLGDRINGLQRQLDHFDLQSDTLMSAMAGIYVDVISPLGPRIQVTGSPAVLQS
                     PQVQAKVRASLLAGIRAAVLWHQVGGGRLQLMFSRHRLTTQAKQILAYLTPEL"
     gene            complement(11506..12612)
                     /gene="mnmA"
                     /locus_tag="OPV72_002719"
     CDS             complement(11506..12612)
                     /gene="mnmA"
                     /locus_tag="OPV72_002719"
                     /EC_number="2.1.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309632.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HCR9914971.1"
                     /translation="MSESPKKVIVGMSGGVDSSVSAWLLQQQGYQVEGLFMKNWEEDD
                     GEEYCTAAADLADAQAVCDKLGIELHTVNFAAEYWDNVFELFLEEYKAGRTPNPDILC
                     NKEIKFKAFLEFAAEDLGADYIATGHYVRRADVNGKSRLLRGLDGNKDQSYFLYTLGH
                     EQIAQSLFPVGELEKPQVRKIAEDLGLVTAKKKDSTGICFIGERKFRDFLGRYLPAQP
                     GKIITVDGDEIGEHQGLMYHTLGQRKGLGIGGTKDGSEDPWYVVDKDVENNVLIVAQG
                     HEHPRLMSVGLIAQQLHWVDREPFTGTLRCTVKTRYRQTDIPCTINALDDDRIEVIFD
                     EPVAAVTPGQSAVFYSGEVCLGGGIIEQRLPLTV"
     gene            complement(12666..13127)
                     /locus_tag="OPV72_002720"
     CDS             complement(12666..13127)
                     /locus_tag="OPV72_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HCR9914972.1"
                     /translation="MFKPHVTVACIVHAEDKFLVVEETINGKSLWNQPAGHLEADETL
                     AQAAARELWEETGITAQPQYFIRMHQWIAPDKTPFLRFLFAIKLDHICATAPHDNDID
                     CCRWVSADEILNAPNLRSPLVAESIRSYQTGQRYPLSIVGEFNWPFTEGVK"
     gene            complement(13139..13468)
                     /locus_tag="OPV72_002721"
     CDS             complement(13139..13468)
                     /locus_tag="OPV72_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1311 domain-containing protein"
                     /protein_id="HCR9914973.1"
                     /translation="MKRLLIAFALLTPLSVNAASFDCQKAQAADEKAICAHLTLNDKD
                     VEMHTKYQFLKGLFAMGSRGALQDAQQSWLKQRQQCKADVTCLTKAYNERLKQLDAIY
                     DHIDKPL"
     gene            complement(13465..14130)
                     /gene="rluE"
                     /locus_tag="OPV72_002722"
     CDS             complement(13465..14130)
                     /gene="rluE"
                     /locus_tag="OPV72_002722"
                     /EC_number="5.4.99.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(2457) synthase RluE"
                     /protein_id="HCR9914974.1"
                     /translation="MRQLISSENTMQKTSFRNHYVKRFSSRQASKSRKENQPKRVVLF
                     NKPYDVLPQFTDEAGRRTLKDFIPVQGVYAAGRLDRDSEGLLVLTNDGALQARLTQPG
                     KRTGKIYYVQVEGIPDNAALQALRTGVTLNDGPTLPAGIEIVAEPDWLWPRTPPIRER
                     KNIPTSWLKVTLYEGRNHQVRRMTAHVGHPTLRLIRYSMGDYTLNGLDNGQWCEIAQE
                     KDR"
     gene            14302..15552
                     /gene="icd"
                     /locus_tag="OPV72_002723"
     CDS             14302..15552
                     /gene="icd"
                     /locus_tag="OPV72_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent isocitrate dehydrogenase"
                     /protein_id="HCR9914975.1"
                     /translation="MESKVVVPVEGKKITLQNGKLNVPENPIIPFIEGDGIGVDVTPA
                     MLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAETLDLIRDYRVAIKGP
                     LTTPVGGGIRSLNVALRQELDLYVCLRPVRYYQGTPSPVKHPELTDMVIFRENSEDIY
                     AGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAI
                     TNDRDSVTLVHKGNIMKFTEGAFKDWGYQLARDEFGGELIDGGPWLKIKNPNTGKEIV
                     VKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGIGIAPGANIGDECAL
                     FEATHGTAPKYAGQDKVNPGSIILSAEMMLRHMQWFEAADLIVKGMEGAIAAKTVTYD
                     FERLMDGAKLLKCSEFGDAIIANM"
BASE COUNT         3812 a         3852 c         4044 g         3887 t
ORIGIN      
        1 aggtatgtgg gtatgtggtg gtggtatttc aagctgtttt aagccacaca tcgtcattgt
       61 ttctaaaaat gcgttttgct gagtactttc ggatatattc gcatgctgta aaatgcgcgt
      121 tgtcttttca atcccagact gaattttcgc tgccaggtag gttgcctttt cttgcgtttt
      181 ccactcatct aaatttcctt ttctccattc agaatataaa tacccctcta tgttgtctaa
      241 tggaaccgat aatgtcggcg cgccagcagg gttgagacat aatgtcgaag ggagggggta
      301 atctacgatt tcgctatatc ttctattaat catggccgtc atttgtggat gcggttttaa
      361 aatatcgggg cgatctttta ttaaaaaata agcattcccc atgacttcac agctaaaggt
      421 atcggtattt tgagtgatac gtaacaattc gttttcttcg ttttgatcca tgatgcgaag
      481 aataatcgtg tcatcatttt catgaggatt atgaacctga aatctatctc tttgcgatgc
      541 gcaggctaac tcttttaact caaaaaaaat ctctgtaaat cgctctcgtg tgggggtgcg
      601 atcggcaaac aacatctcat gtagacaacg gtccgctttt gctttgccag tagaaaaaaa
      661 gaagtcttta atttttttcc ataaaacttt ccaccatgct tctttcgtat tccttgggga
      721 gttggtaagg atttcacttt ttaaaaaacc attccctata gtaatcggca tattaatctc
      781 acttatactg gagtaaaaat gactacataa ttgattaaat caactctttt tatctcaact
      841 gcgggcgcat cggatgtaat ataattttta aaagagactg gcaatcagta taaaacctga
      901 gagcttcgcg tataaacgca ttactgtctg cgatagcgtc gctacaggta aaaataaaag
      961 aaggcctacc gcggatgatg ttgtagattt gcaatactgg cggcaacttc tttcatgcgt
     1021 tttttatgcc ggaggcatga agtttaccct tgaataaact tcatgcctgg atgcgtgtgg
     1081 atttgttagc gttgcgcaat taatcgctta tatcactcac cttcttattc aataagcggg
     1141 aagcccgcca gtaaatcaac agcatgagtc ccatcacaat ggtcagcgta atgctggtag
     1201 ccgcgccaaa cggccagtcg cgaatattca ggaactgtac cttaatgacg ttaccaatca
     1261 gcaggttttt cgcgccaccc attaaatcgg agacgtagaa caggcccatt gccggtagca
     1321 tcacgagcag gcaaccggcg acaatgcccg gcatggttaa tggaataatg atgcggatga
     1381 acgtttgcat tttactggca ccgagatcgc gagcggcctc cagtagcggt ttgtcgagct
     1441 tctcaatgct ggagtagagc ggcatgacca taaacggcag caaaatgtaa accaggccga
     1501 taataacggc gctcggggtg aacatgatgc gaatcggcgt atcaatcacg cccagccaca
     1561 gcaggaattc attgagataa cctttagtgc tcaggaatat ttttagccca tagatgcgga
     1621 tcagtgagtt ggtccagaaa ggaacaatca gcaaaaacag caataacgga cgtatctttt
     1681 ccggtaactt cgccagaaac caggcgaaag gatagcccag caccaggcag gagagggtgg
     1741 cgatcagcgc catattcaga gagtgcagga gcacttcaaa atagagcgga tcgagcaggc
     1801 gtgcgtagtt atccagcgta aagaccatct tgacgaaact ggcgtcgtca cgggtcagaa
     1861 agctggtgcc aatgatcatc aggttgggca gaaaaacaaa caacacaagc caaccgacga
     1921 tagtgacaat cactacattc tggaatttac ttgtgttctt catcagccag tacgacctcc
     1981 cagctttcta cccaactaat ggccattttt tggtcaagtg aatggtcgaa gtcaggatcg
     2041 tcttcgttga agaattcgct gaccatcacc attttgccat tttccagttc aaccaccgac
     2101 tccagcgtca tacctttgta attgcgctcg cgcacgtagc cgataagccc ttcgatgtgg
     2161 ttatcatcgt tgatctcttc gacgcgtaga tcttccggtc gcagcaggac gttcagtttt
     2221 tggcccagtt cgacagcgaa attgacgtat atattgcact cccgaccttc tacgctggcg
     2281 cggacgcgct gttcatcaag ccgttcaatg acggttgcgt caaagcggtt aatttcgccg
     2341 ataaaaccgg cgacaaacag gctttttggc tcttcataga tttcacgcgg cgtgccgtct
     2401 tgctcaatca cgccattacg cattaccacg atacgatcgg acatggtgag cgcttcttcc
     2461 tgatcgtgag tgacaaaaac aaacgtgata ccgagtttac gctgtaatgc tttaagctcg
     2521 ttctgcattt gtttgcgcaa tttatagtcc agcgcggaga gcgattcgtc cagtaataac
     2581 aggcgaggtt tattcaccac cgcgcgagcg atagccacac gctgctgctg tccgccggaa
     2641 agctggtgcg gtttacgttg tgcaaactct tcaagctgca ccatacgcag cgcatcggtc
     2701 acgcgaggcg ctatctcggc ggctggtgtt ttttgcattc gtaagccaaa cgcgacattt
     2761 tcaaacaccg tcatatgcgg aaataaagcg tagctttgaa atacggtatt tacataacga
     2821 ttttcggcgg gaacgtgggt gatatcctgg ttatccaaca tgatatgccc ggcatcaacg
     2881 gtttccaggc cggcaatcag gcgaagaacg gttgttttac cgcagccgga agggccaagc
     2941 agcgtgagga attcgccatt gttaatggtc aaatccagct gtgaaatgac ctctttgcca
     3001 tcgaaacttt tgctaattcc cgacaaaagc accagcggtg aaagcgaacg cggttgttta
     3061 ttcaatttct tactctgtcc catgtaaacg caacggatgg ctgaccgctg cggggtttgt
     3121 ggttaaccac cttaatcact cttaatgagg gcggtcattc tacggcaaac caccgtgatc
     3181 gccaatcctt gttgcgaatt actgacttag ctttatagtc agaaagcgtg tcaaagtgaa
     3241 atattcttgt ttgcagggat aaaagtgacc tgacgcaata tttgtctttt cttgcttatt
     3301 aataatgttg tcacgaaaag tgagggtgac tgcatggata aactacttga gcgtttttta
     3361 cactacgtat cgctggatac ccaatcaaag tcgggtgttc ggcaggttcc cagcactgag
     3421 gggcagtgga agttactacg tttgctcaaa cagcagctcg aagagatggg gctggttaac
     3481 attacattaa gtgaaaaagg gacgttgatg gcgacgctcc cggccaatgt tgagggggat
     3541 attcccgcca ttggttttat ctcccatgtg gatacctctc cggatttcag cggtaaaaac
     3601 gttaacccgc agattgtcga gaattatcgc ggcggcgata tagcattagg gattggcgat
     3661 gaggtgttgt cacccgtgat gttcccggta ctgcatcaat tactgggaca gacgctgatt
     3721 actaccgatg gtaagacatt gctgggcgcg gacgataaag ccggtgttgc ggagatcatg
     3781 accgcgctgg cggtgctgaa aggtaatcct attccccacg gcgaaattaa agtggcgttt
     3841 acgcctgacg aagaggtagg gaaaggcgcg aagcacttcg atgttgagga atttggcgcg
     3901 cagtgggcct atacggtcga cggcggcggc gtgggagaac tggagtttga aaacttcaat
     3961 gccgcctcgg tgaatatcaa aatcgtcggc aataacgtgc atcctggtac ggcgaaaggc
     4021 gtgatggtca atgcgctgtc gttggcggcg aggattcacg cggaagtgcc ggcggatgaa
     4081 gcgcctgaaa ccactgaagg ttacgaaggg ttttatcatc tggccagcat gaaaggcacc
     4141 gttgaccggg ccgaaatgca ctacatcatt cgcgatttcg accgtaagca gtttgaagcg
     4201 cgtaaacgca aaatgatgga gattgccaaa aaagtcggca aggggctgca tccggactgc
     4261 tatatcgaac tggtgattga agacagttat tacaatatgc gcgaaaaagt ggttgagcat
     4321 ccgcatattc tcgatatcgc ccagcaggcc atgcgcgact gtcatattac gccggagatg
     4381 aaaccaattc gcggcggtac agacggggcg caactgtcgt ttatgggcct gccgtgtcct
     4441 aatctcttta ccggcggata taactatcat ggtaaacatg agtttgtgac gctggagggg
     4501 atggaaaaag cggtacaggt gattgtacgt atcgcggagc tgacgggtaa gcgcggccag
     4561 tagcgaatgt tacacattgt ggtgaagcgt tttattattt atggcgggat attttccgcc
     4621 ataaattttt ctgcctggag cgccgaatat acgccttcct ggtcccagcg ccagcaacaa
     4681 tctgcagcat gttttatgac cggcgatgaa acctgcatga cgtttattga tgatgcggtg
     4741 aggctggcct cgcggcaata tggcaaacgc tcaatacagc ttgttcgtag cctgctatta
     4801 caaagcgata tttatcaatg gctgggtaaa ccggagttaa cgccgcaaat gctgctgcga
     4861 gcgcgggcaa tcatgaaaac atttccggcg ggcacttatc cgggcgatcg ggccgatatg
     4921 tttgaacacc tggcggcctt ttatgtttac ggtgacgatc gccatataga gtattcaccg
     4981 acagagcagt ggcgatacga gatcaaggtt gattaccgtc agcggatagc ctggcaagag
     5041 caggcattaa cgtggcgtct taaagacaaa aagacatcga cggaagcgtt ggtttatacc
     5101 ttaaacagga tgcgcgacgc ttattctgat gcgctggaag agcgggatgt cgaatgtgat
     5161 agtgcgcgta aagcctatta tttggcgaag atagacgcag cggagcggca gtggctgagc
     5221 gttattttac gggataaaac ctgggataat cgtgagcgcg tcgcctcttt tttgcagcag
     5281 aaagcggata ttgcttataa tgcagggcat attagcgagg cgattaatgc gctaagtcag
     5341 gcgctaaaaa ttgagcaaac gctttatggc accgaattcg gcgaaatgac ggttgacagc
     5401 aataatcttg ctggctttta tgcacagggc catcattata aggaagcgaa agatctctac
     5461 cttaaactta tcgcgtatta ccagagccgt ttaacgccaa tggcgacggt aatatcacga
     5521 ttacgctttt atttgcccga aaacatcgac ctggacagta cctcccccta tctcccattg
     5581 ctggaagaat ataaacgtcg gcagtccgac gtatccatgg tgttgtatgg tatttcgctg
     5641 ctttataaga ataatcaaca gcttgaacaa gcaaaagact ttgcggaacg cgcctttacg
     5701 cttgatgccg tagcttatcc agcaaagatg cagtatgaac gattacagca actggctaat
     5761 attgccgaag gtcttggaga taacgcgcag gcgcggcgct atcggcaaat gtcatttcgc
     5821 catcgaatgg cccactcgat ttatccgggc gatccgcaat ataacgattt cgccaaacct
     5881 ggcggcgatc gttgtggata gtttgcgtca gcccggcggt cgccgggcat tgcgatgttc
     5941 ttatccttcg aaaaaccagt atccgctatt caccagcgcc gccagcatcg cgaggaagga
     6001 agggtcttcc agcgcatcgc cgaagttttc agcggtcagt acaatatgac tggtgagcgc
     6061 ttccagagcg gggcgatgcg gagagtctat tttttcgcca ttcgcataga cttcatcgcc
     6121 gatacgcaat acgcgaagcc cgccgagacg tactaatgcc tcgccttgct ttaaggcatc
     6181 gtaaatttcg tctggctgat acggcggctc cggcggcgca atatccagtt cgtggcgtga
     6241 ctgagagata aactcgccaa gccactgttg gaaatgcgcg ggctgattga tcaaatcgag
     6301 catcatatta cgcagtttat ccatctcctg cggcaggata tccgccggat gtttgcggga
     6361 cggcatatcc ggatcgctgt agtatgtgtt gcccagatcc cgttgcagga cgtaatcggc
     6421 aaaaccgctg atcagctcac ggctattggg cgcgcgaaaa ccgactgaat agttcatggc
     6481 gttttccagc gcataccctt catgcgggaa tccaggcgga atatacagaa tgtcgcccgg
     6541 ctccagctct tcgtcaataa tggcctcgaa cggatcgact tgtaacaggt cgggatgcgg
     6601 gcagtgctga cgcatttgca gcttttcgcc cacgcgccag cgacggcgac cggttccctg
     6661 gataataaac acatcatact gatccagatg cgggccaacg ccgccaccgg gaacggaaaa
     6721 ggagatcatc agatcgtcga tacgccagtc cggcagagcg cggaacgggc gcatcagcgc
     6781 ggcggtgggt tcatgccagt ggtttaccgc ctgtaccagc agcgaccagt tgctctcacc
     6841 cagatgatcg tagctttcga aagggccatg gctgacctgc catttgccat cctgatggct
     6901 aacgagacgg ctgtcgattt cgctttccat cgccagcccc gccagctcat ccggcgagag
     6961 cggatcaata aagttggtaa acccacgttt taagaccacc gggcgttttt gccagtggcg
     7021 ttcaagaaag tcgggccagt taagagttaa ttggtattcc atgttaagta tccgcaggct
     7081 ggtatctgac accgattata acggatgctt aacgagatgc gtggaagaac gcacagaaat
     7141 gtttattcct ctttctgtgt gggatgctgt cggccaaaaa cgacctccat acgggcgcca
     7201 ccgagcagac tgtcgctggc aatgatctgc ccggcgtatt gttccgtaat ctcgcgcgcg
     7261 acagccagcc ccacgccttg tcctggtcgt agggtatcgg cgcgctgacc gcgatcaaac
     7321 accagggaac gtttgctgtg gggtatgcct gggccgtcat cttcgacgaa aatatgcaaa
     7381 tgatcgtcgg tctggcgagc cgaaatctcg acaaactcca gacaatattt acaagcgttg
     7441 tccagtacgt tgcccattac ttcgacaaag tcgttttgct cgccgacaaa actgatctct
     7501 ggtgaaatat ccatactgat attcacccct ttacgctgat aaactttatt gagcgcggag
     7561 atcaggttat ctaacaacgg cgcgacggga tgcagttcgc ggcttaacaa cacgccgcta
     7621 ccgcgcatac tggcgcgatg cagataatag ccgatctgct gggaaatccg actgatctgt
     7681 tccagcatca ccggttcagc tttgctgacg ctcatctttt cgttgcgtaa agagcgtaac
     7741 gtactctgca aaaccgcgag cggcgttttt aaactgtgcg tcaggtcggt tagggtcgtg
     7801 cggtatttgt tataacgttc gcgctcgctt ttgagcagtt gattaaggtt gcgcacaagg
     7861 ctggtcagct cacgcgtcgt ctccggattg agcatttcgc ggtgatgatc ttcaagttcg
     7921 cggacttccc gcgccagcgc ctcgataggg cgtaagctcc accaggcggc gatccacagt
     7981 aaaggaatga ctaacagtaa attggcggcc agcacgtata cgaaccagct ccacaccata
     8041 taggagcgtt ttagctctat cggaatggta tcgaccacca cgatggttaa ctgcggcatc
     8101 cgcgtcgtgg caggataaat atttaccgct accgagtggg tcatctccgc atcatcgtca
     8161 tcttcacgta cttctttgag tttttcctgc gcggaatggt cctcgctcaa cagcgtgctg
     8221 gtggcgtcta cgttggtttc aatttcatgg aagccgttcg tttttaacca ttccggttga
     8281 atgcttttaa tcagccaggg gatgttgcgc tgcgtccata ataatttgcc cgtttcatcg
     8341 taaatcagcg tcatggtcgg gctttgcatg tccagatttt caggcagctc aacgctgatt
     8401 ttattatttt cccatttggc gagggtataa aacaggttgc tttcgccgcg cagcagacga
     8461 aacgtggttt tatcaaaact tacgctatag ccgaccagcg ccactatgcc atatgccaga
     8521 gaaagcacca gcacgacgcc ggctgtcgcc agcaaaaaac gaacccgcag cgacagcggc
     8581 agaaaatggc gagcaaattt attcattagc gcaattcaaa aagatatcct tgtccgcgta
     8641 cggtggtaat gacatcgtgc ggatactggg cctgtatttt tttccgcaga cgccccatga
     8701 gaacatcaat ggtatgactt tcccgcagtt ccgcatccgg atacagctga agcatcagag
     8761 aatctttgct gaccacttta ccgttgttac ggataagcgt ttccataatg gtgtattcga
     8821 acgccgtgag tttgatgacc tcttcattga cggataattc ccggcgtgag agatccacct
     8881 ggaaaggcga gatgttgatc acctgggagg ccagaccgct attacggcgc attaacgcct
     8941 gcatacgcgc cattacctct tcgatgtgga atggcttcgt cacgtagtca tcggccccgg
     9001 agctgagaac ctcgacttta tcctgccagc cttcgcgcgc ggttaacacc agaaccggca
     9061 gtgaaacatc actgctgcgc cagcggcgta ttaaggaaag gccgtcttca tccggcagac
     9121 ctaaatcgac aatagcgata tccggaaggt gttcattaag gtagtaatca gcttccctgg
     9181 catcttctgc ggcatcgacc tggtgacctg aatcctggag ctgaaccttc aggtggtggc
     9241 gtaataatgc attatcctct acaaccagta cgcgcatcat ctcttctccc ttgtgttaac
     9301 aataagaaca gtctagcgtt gattatggtg ctttggggat aaacagttaa taaaccagac
     9361 aaatagtcac cctctttctg aagaaaagag ggtgaggcac acattattta agttcgtcga
     9421 ccagattcac agcgcgaccg atataatttg ccggcgtcat ggctttaagg cgcgtttttt
     9481 ctgcttccgg cagggccaga ctatcaataa gctgtttcat tccttcggca tcgacacgct
     9541 tgccacgggt caactctttc agtttttcat atggtttttc aatgccatag cggcgcatga
     9601 cggtctggat cggttcggct aatacttccc agttgtgatc cagttcgtca agcagatgat
     9661 cgcggttcac ttccagcttg ctgacgccct tcagggtcga ctgataagcg ataagcgcat
     9721 agccgatgcc gacacccagg ttacgcagga cggttgagtc ggtcagatcg cgctgccagc
     9781 gggaaaccgg cagtttgttt gccagatggt gcaacactgc attagacaga ccgaggttgc
     9841 cttctgagtt ttcaaagtca atggggttaa ctttatgcgg catggtagaa gaaccgatct
     9901 ctccggcgat ggttttctgt ttgaaatggt tcaacgcaat atagccccag acatcgcgat
     9961 cgaaatcgat caggatggtg ttaaagcgcg cgatacagtc aaacagttcc gcaatataat
    10021 catgcggttc aatctgggtg gtgtaagggt tccactggat gcccagcgag gtgacgaact
    10081 cttcgctgaa ctgatgccag tcaacttccg gataggcggc gatatgcgcg ttatagttgc
    10141 ctacggcgcc gttaatttta ccgaggatct ccacctgatt gagctggcgg aactgacgct
    10201 ccatccgata cgccacgttc gccatctctt tacccagagt ggaaggtgtt gccggctggc
    10261 cgtgggtgcg ggagagcaga ggaatatcgc gatactgcgt ggcgagatct ttaaccgcgt
    10321 taatcacctg acgccagtaa ggcaggatca cttcatcgcg cgcagttttg agcattaacg
    10381 cgtgcgacag gttgttaata tcctcagagg tgcaggcaaa gtggataaat tcggaaacgt
    10441 catgtagcgc cgggatcgcg gcggcttttt ctttcagaaa atactcaacc gctttcacat
    10501 cgtgattcgt ggtgcgctca atggttttaa tgcgcgcggc atcttcttca ttgaagtttg
    10561 ccacaagcgt atccaggtaa ccgtttgcgt cggcagcaaa agcaggaact tccttgatcg
    10621 ctgcgtgcgc ggctaatttc tgcagccaac gtacttcgac ttgtacacga aatttcagca
    10681 aaccgtattc gctaaaaatt ccgcgcagcg cgctgacttt atcgccgtag cgtccatcga
    10741 caggggaaac ggcggtcagt gaggataatt ccatagatca taactccggg gttaaataag
    10801 caagaatttg ttttgcctga gtcgtcaggc gatgacgaga aaacataagc tgtaggcgac
    10861 caccgcctac ctgatgccag agcacggctg cacggatgcc tgccagtagc gaggcgcgga
    10921 ctttggcctg cacctgcgga ctttgcagaa cggccgggga gcccgtcacc tgaatgcgcg
    10981 ggcccaatgg gctaatcaca tccacgtaga tgcccgccat ggcgctcatt aacgtgtctg
    11041 actgtaaatc aaaatggtca agctggcgct gcaggccgtt aatgcgatcg cctaacgtat
    11101 tcaacgcgcc tttggcggat gacagcttgc gctccagcac catcaggcta agcgtataac
    11161 gcgtcagttc ggcgttaagt ccttgtcggc tgctggcatt cagcacgccg agcagtgttt
    11221 ccagaccaag acgcaggtta gcttcgctgc cgccgaacac gcccagagta gaactgggat
    11281 tcatatcaat gacactgttg agtgaaacgt gcaacgcgtc ggcatcacag tgtccctggt
    11341 gcgccagttg ttgcaccagg cgtgccgact ggcaaatgcc agacagcgcg agggtgatgt
    11401 cataataatt ctttgccaca atcactgctt ccttgtatca aataaaatac acttcatctt
    11461 ttaagccgct ttgaggtgac ttgaatggtg ttgtgtattg aataatcaga ccgtcagcgg
    11521 cagtcgctgc tcgataatgc cgccgcccag gcagacttct ccgctgtaaa agacagcgga
    11581 ctggcccggc gtaacggcgg caaccggctc gtcaaaaatg acctcgatac gatcgtcatc
    11641 cagcgcgtta atcgtgcacg gaatatcggt ctggcggtag cgggttttta ccgtacagcg
    11701 cagggtgccg gtgaacggtt cgcgatcgac ccaatgtagc tgctgggcga tgaggcctac
    11761 cgacatcagg cgtgggtgct catgcccctg ggcgacaatt aacacattgt tttcaacgtc
    11821 tttatccacc acataccagg ggtcttcgct accgtctttg gtgccgccaa ttcccagccc
    11881 tttacgctga ccgagcgtat gatacatcag accctgatgc tcgccgattt catcgccgtc
    11941 aacagtaatg attttccccg gctgcgcagg cagatagcgc cctaaaaagt cgcggaattt
    12001 gcgctcgccg ataaagcaga taccggtaga atcttttttc ttggcggtta ccagccccaa
    12061 atcttcggcg attttacgca cctgcggttt ttccagctcg ccaaccggga acagactttg
    12121 cgcaatctgc tcatggccaa gcgtatagag gaagtagctc tgatctttgt taccgtcgag
    12181 cccgcgcaac aaccggcttt tgccgtttac atccgcgcgg cgaacgtagt gaccggtggc
    12241 gatatagtcg gcgcctaaat cttctgcggc aaattcaagg aaggctttaa atttgatctc
    12301 tttattgcac agaatatccg gattcggcgt acggcccgct ttgtactctt caaggaacag
    12361 ttcaaagacg ttatcccaat attctgcggc aaaattaacg gtatgcagtt caatgccaag
    12421 cttgtcgcac acggcctgcg cgtcagccag atcggctgcc gcggtgcagt attcctcacc
    12481 atcgtcctct tcccagttct tcatgaacag gccttctacc tgataaccct gttgttgcaa
    12541 cagccaggcg gaaacggagg aatcgacacc gccggacatg ccgacgatca ctttttttgg
    12601 gctttctgac attggaatac tcgcgacatt gaacttcaag gcggcgtatt ctatcacgca
    12661 gccctttact tgacaccctc tgtaaacggc cagttaaatt cgcccactat agataagggg
    12721 taacgttgtc ccgtttgata actgcgaatg ctttcagcca ccagcggaga acgtaaattc
    12781 ggcgcgttca gaatctcgtc ggcgctcacc caacggcagc aatcgatgtc attgtcatgg
    12841 ggggcggtcg cgcaaatatg atcaagcttg atagcgaata aaaagcgcag gaacggggtt
    12901 ttatccggcg caatccactg atgcatacgg ataaaatact gtggttgcgc cgtgatgcca
    12961 gtctcttccc acagttctcg cgcggcggcc tgcgccagcg tttcatctgc ctccaggtgt
    13021 ccggcaggtt gattccataa cgatttaccg ttgatggtct cttccaccac cagaaattta
    13081 tcttcggcat gtacgatgca ggcaacggtc acgtgcggct tgaacatagg catccttatt
    13141 aaagcggttt atcaatgtgg tcatagatcg cgtcaagctg tttcagacgc tcgttataag
    13201 cttttgtcag gcaggtgacg tcggccttgc actgctgacg ctgtttaagc cagctctgct
    13261 gggcgtcctg cagcgcgccg cgactgccca tcgcgaacaa ccctttcaga aactgatatt
    13321 tggtgtgcat ttccacgtct ttatcattca gcgtcaggtg cgcgcagata gccttttcat
    13381 ccgcagcctg cgctttctgg cagtcgaagc tggccgcatt aacggataac ggtgttaata
    13441 aagcaaaagc aatgagaagc cgtttcatct gtctttctcc tgtgcgatct cgcaccactg
    13501 tccattatcg aggccgttga gcgtgtagtc gcccatgctg taacgaatta atcgtagagt
    13561 gggatgaccg acatgcgctg tcatgcgtct tacctggtgg ttgcggcctt catataaggt
    13621 gacttttagc caactggtgg gaatattctt ccgttcgcga atcggcgggg tgcgcggcca
    13681 cagccagtca ggctccgcga caatctcaat accggcgggc agggtagggc catcgttgag
    13741 cgtgacgcca gtacgaagcg cctgcagcgc tgcattatcc gggatgcctt ctacctgaac
    13801 atagtaaatc ttgccggtgc gtttgcccgg ttgcgtgagg cgcgcctgca gcgcgccgtc
    13861 attagtcagc accaaaagcc cttcgctgtc gcggtccagg cggcctgcgg cataaacgcc
    13921 ttgcacagga ataaaatctt ttaacgtgcg gcgacctgct tcatccgtga actgcggcaa
    13981 cacatcgtaa ggtttattga acaaaaccac gcgttttggc tggttttctt tccgtgattt
    14041 agatgcttgt cgtgagctga atcgcttaac gtagtgattt ctaaaagaag ttttttgcat
    14101 ggtgttttca gaacttatta attgccgcat tatagcgcaa taatgagtgt ctttcatggc
    14161 ggcaaacaat agggtagtat tgacatgctc attacaaaac attaacaaaa aattgctcta
    14221 acgcagtcgt gcagcaggac gccattgcac atgcagcgcg atgacagacg agcaaaccag
    14281 aagcgctcga aggagaggtg aatggaaagc aaagtagttg ttccggtgga aggtaagaag
    14341 atcaccctgc aaaacggcaa actcaacgtt cctgagaatc cgattatccc gtttattgaa
    14401 ggcgatggta tcggtgttga tgtcactcca gccatgctta aagtggtcga tgccgccgtc
    14461 gagaaagcct ataaaggcga gcgtaaaatt tcctggatgg aaatttacac cggagaaaaa
    14521 tccacacagg tttacggcca ggatgtctgg cttcccgctg aaacccttga tttaattcgt
    14581 gactaccgcg tagcgattaa aggtccattg accacgccgg ttggcggcgg tatccgctct
    14641 ctgaacgttg ccctgcgtca ggagcttgac ctgtacgttt gtctgcgtcc cgttcgttac
    14701 tatcagggca cgccaagtcc ggtgaaacat ccggagctga ccgatatggt catcttccgt
    14761 gaaaactctg aagacatcta cgccggaatt gaatggaaag ctgactctgc agacgctgag
    14821 aaagtgatca agttcctgcg cgaagagatg ggcgtgaaga aaattcgctt cccggagcac
    14881 tgcggtatcg gtatcaaacc gtgttctgaa gaaggcacta aacgtctggt tcgcgcggcg
    14941 attgaatacg ctattaccaa cgatcgcgat tccgtcacgc tggtacataa aggcaatatc
    15001 atgaagttca ccgaaggcgc gtttaaagac tggggctacc agttggcgcg cgacgagttc
    15061 ggcggtgagc ttattgacgg cggtccgtgg ctgaaaatta agaacccgaa cacgggtaaa
    15121 gagatcgtgg ttaaagacgt tatcgccgat gcgttcctgc aacaaatcct gttgcgtccg
    15181 gcggaatacg acgttatcgc ctgtatgaac ctgaacggtg actatatttc cgatgccctg
    15241 gcggctcagg ttggcggtat cggtattgca ccgggtgcga atatcggcga cgaatgcgcg
    15301 ttgtttgaag cgactcacgg gactgcgccg aaatatgcgg gccaggataa agtcaaccca
    15361 ggctccatta ttctgtctgc ggagatgatg ctgcgccaca tgcagtggtt cgaagcggcg
    15421 gatctgattg ttaaaggtat ggaaggcgcg attgccgcga agaccgtgac ctatgacttt
    15481 gaacgcctga tggacggcgc taagctgctg aaatgtagtg agtttggcga cgcgattatc
    15541 gcaaatatgt aatatcgata attgttaaaa acaaaaacgg gggcttaacg tcccc
//
LOCUS       DAJVBX010000104        15283 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.104, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000104 DAJVBX010000000
VERSION     DAJVBX010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 15283)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15283)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15283
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.104"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            46..1647
                     /gene="aceB"
                     /locus_tag="OPV72_002724"
     CDS             46..1647
                     /gene="aceB"
                     /locus_tag="OPV72_002724"
                     /EC_number="2.3.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate synthase A"
                     /protein_id="HCR9914976.1"
                     /translation="MNPQATTTDELTFTRPQGELEKQVLTAEAVEFLTELVTRFTPKR
                     NKLLAARIQQQQDIDNGKLPDFISETTSIRESNWQIRGIPADLQDRRVEITGPVERKM
                     VINALNANVKVFMADFEDSLAPDWNKVIDGQINLRDAVNGTISYTNEAGKIYQLKPDP
                     AVLICRVRGLHLPEKHVTWRGEAIPGSLFDFALYFFHNYKALLAKGSGPYFYLPKTQA
                     WQEAAWWSEVFSYAEDRFNLPRGTIKATLLIETLPAVFQMDEILHALRDHIVGLNCGR
                     WDYIFSYIKTLKNHPDRVLPDRQVVTMDKPFLSAYSRLLIKTCHKRGAFAMGGMAAFI
                     PSKDVERNNQVLAKVKADKALEANNGHDGTWIAHPGLADTAMAVFNEVLGEYKNQLFI
                     TRDEDAPITAEQLLEPCEGERTEAGMRANIRVAVQYIEAWIPGNGCVPIYGLMEDAAT
                     AEISRTSIWQWIHHEKTLSNGKPVTKALFREMLAEEMRVIQDELGEHRYSSGRFDDAA
                     RLMEQITTSDDLIDFLTLPGYRLLA"
     gene            1679..2983
                     /gene="aceA"
                     /locus_tag="OPV72_002725"
     CDS             1679..2983
                     /gene="aceA"
                     /locus_tag="OPV72_002725"
                     /EC_number="4.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate lyase"
                     /protein_id="HCR9914977.1"
                     /translation="MKTRTQQIEELQKEWTQPRWEGITRPYSAEEVVKLRGSVNPECT
                     LAQLGAAKMWRLLHGEAKKGYINSLGALTGGQALQQAKAGIEAIYLSGWQVVADANLA
                     SSMYPDQSLYPANSVPAVVDRINNTFRRADQIQWASGIEPNDPRYVDYFLPIVADAEA
                     GFGGVLNAFELMKSMIEAGAAAVHFEDQLASVKKCGHMGGKVLVPTQEAIQKLVAARL
                     AADVMGVPTLVIARTDADAADLITSDCDPYDSGFITGERTSEGFYRTHAGIEQAISRG
                     LAYAPYADLVWCETSTPDLELARRFADAIHAKYPGKLLAYNCSPSFNWQKNLDDKTIA
                     SFQQQLSDMGYKYQFITLAGIHSMWFNMFDLAHAYAQGEGMKHYVEKVQQPEFAAAKD
                     GYTFVSHQQEVGTGYFDKVTTIIQGGASSVTALTGSTEESQF"
     gene            3084..4865
                     /gene="aceK"
                     /locus_tag="OPV72_002726"
     CDS             3084..4865
                     /gene="aceK"
                     /locus_tag="OPV72_002726"
                     /EC_number="2.7.11.5"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005224531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional isocitrate dehydrogenase
                     kinase/phosphatase"
                     /protein_id="HCR9914978.1"
                     /translation="MPRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQ
                     QAMKSRIHLYDHHVGLVVEQLRCITDGKSTDADFLLRVKEHYTRLLPDYPRFEIAESF
                     FNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFFPDHGWEPLLMRILSDL
                     PLCLPWQNKSRDIRYIIAHLTETLGEDALPRCHVQVANELFYRNKAAWLVGKLTTPDG
                     TLPFLLPIHRTDEGELFVDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILP
                     GKTTAELYMAIGCQKHAKTESYREYLCYLAESDEKFIEAPGIRGMVMLVFTLPGFDRV
                     FKIIKDKFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLDKRQIDPALMAL
                     LRQEAPEKITDLGEHIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAA
                     ANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPPARYPEDELASEPWYSV
                     SPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQTRIKEGHVEDVYAYRRR
                     QRFSVRYETDRRPDKAFAPPSGNVRRA"
     gene            complement(4910..5734)
                     /gene="iclR"
                     /locus_tag="OPV72_002727"
     CDS             complement(4910..5734)
                     /gene="iclR"
                     /locus_tag="OPV72_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate bypass operon transcriptional
                     repressor IclR"
                     /protein_id="HCR9914979.1"
                     /translation="MVAPVPAKRGRKPAATTAPVTGQVQSLTRGLKLLEWIAESNGSV
                     ALTELAQQAGLPNSTTHRLLTTMQQQGFVRQVGELGHWAVGAHAFIVGSSFLQSRNLL
                     AIVHPILRKLMEDSGETVNLAVLDQSDHQAIIIDQVQCTQLMRMSAPIGGKLPMHASG
                     AGKAFLSQLSEEQVTSLLHRKGLHAYTHATLVSPLHLKDDLAQTRKRGYSFDDEEHAL
                     GLRCVASCIYDEHREPFAALSISGPCSRITDDRVTELGAMVIKAAKEVTLAYGGFR"
     gene            6038..9721
                     /gene="metH"
                     /locus_tag="OPV72_002728"
     CDS             6038..9721
                     /gene="metH"
                     /locus_tag="OPV72_002728"
                     /EC_number="2.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HCR9914980.1"
                     /translation="MSSKVEQLRAQLNERILVLDGGMGTMIQSYRLHEEDFRGERFAD
                     WPCDLKGNNDLLVLSKPEVIAAIHNAYFEAGADIIETNTFNSTTIAMADYRMESLSAE
                     INYAAAKLARACADEWTARTPEKPRFVAGVLGPTNRTASISPDVNDPAFRNITFDQLV
                     AAYRESTKALVEGGADLILIETVFDTLNAKAAVFAVKEEFEALGVDLPIMISGTITDA
                     SGRTLSGQTTEAFYNSLRHAEALTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAG
                     LPNAFGEYDLDADTMAKQIREWAEAGFLNIVGGCCGTTPEHIAAMSRAVAGLSPRQLP
                     DIPVACRLSGLEPLNIGDDSLFVNVGERTNVTGSAKFKRLIKEEKYSEALDVARQQVE
                     SGAQIIDINMDEGMLDAEAAMVRFLSLIAGEPDIARVPIMIDSSKWEVIEKGLKCIQG
                     KGIVNSISMKEGVEAFIHHAKLLRRYGAAVVVMAFDEQGQADTRERKIEICRRAYKIL
                     LEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQDFIGACEDIKRELPHALISGGVSNVS
                     FSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDNLPAELRDAVEDVILNRR
                     DDGTERLLDLAEKYRGSKTDEAASAQQAEWRSWDVKKRLEYSLVKGITEFIEQDTEEA
                     RQQAARPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPFIEASK
                     EKGSSNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDLGVMVPAEKILRTAREVNA
                     DLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKAHTAVKIEQNYSGPTVY
                     VQNASRTVGVVAALLSDTQRDDFVARTRKEYETVRIQHARKKPRTPPVTLEAARDNDL
                     AFDWERYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKYPRILEDEVVGVE
                     AQRLFKDANDMLDKLSAEKLLNPRGVVGLFPANRVGDDIEIYRDETRTHVLTVSHHLR
                     QQTEKVGFANYCLADFVAPKLSGKADYIGAFAVTGGLKEDALADAFEAQHDDYNKIMV
                     KAIADRLAEAFAEYLHERVRKVYWGYAPNESLSNDELIRENYQGIRPAPGYPACPEHT
                     EKGTIWQLLDVEKHTGMKLTESFAMWPGASVSGWYFSHPESKYFAVAQIQRDQVTDYA
                     FRKGMSVEDVERWLAPNLGYDAD"
     gene            9978..11609
                     /locus_tag="OPV72_002729"
     CDS             9978..11609
                     /locus_tag="OPV72_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HCR9914981.1"
                     /translation="MLTLLHLLSAVALLVWGTHIVRTGVMRVFGARLRTVLSRSVEKK
                     PLAFCAGIGVTALVQSSNATTLLVTSFVAQDLVALTPALVIVLGADVGTALMARILTF
                     DLSWLSPLLIFIGVIFFLGRKQSRAGQLGRVGIGLGLILLALELIVQAVTPITQANGV
                     QVIFASLTGDIMLDALIGAMFAIISYSSLAAVLLTATLTAAGIISFPVALCLVIGANL
                     GSGLLAMLNNSAANAAARRVALGSLLFKLIGSLVILPFVHPLANLMDELPLPKSELVI
                     YFHVFYNLVRCLAMVPFAELMARFCKRIIRDEPELDTHLKPKHLDVSALDTPTLALAN
                     AAREVLRIGDAMEQMMEGLKKVMHGEPREEKALRKLADDVNVLYTAIKLYLARMPKDE
                     LAAEESRRWAEIIEMALNLEQASDIIERMGSEIADKSLAARRAFSEEGLKELDALYDQ
                     LLSNLQLAMSVFFSGDVTSARRLRRSKHRFRILNRRCSHAHVDRLHQQNVQSIETSSL
                     HLGLLGDMKRLNSLFCSVAYSVLEQPDQDEERGEY"
     gene            complement(11699..12388)
                     /gene="pepE"
                     /locus_tag="OPV72_002730"
     CDS             complement(11699..12388)
                     /gene="pepE"
                     /locus_tag="OPV72_002730"
                     /EC_number="3.4.13.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepE"
                     /protein_id="HCR9914982.1"
                     /translation="MELLLLSNSTLPGKAWLEHALPLIANQLNGRRSAVFIPFAGVTQ
                     TWDEYTDKTAEVLAPLGINVTGIHRVADPLAAIEKAEIVIVGGGNTFQLLKESRERGL
                     LAPVADRVKRGALYIGWSAGANLACPTIRTTNDMPIVDPNGFDALDLFPLQINPHFTN
                     ALPEGHKGETREQHIRELLVVAPELTVIGLPEGNWIQVSNGQAVLGGPNTTWVFKAGE
                     EAVALEAGHRF"
     gene            12460..12561
                     /locus_tag="OPV72_002731"
     CDS             12460..12561
                     /locus_tag="OPV72_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914983.1"
                     /translation="MAHDVARVTGNARSLKVTPGQICHLVSPEKLQV"
     gene            12596..13135
                     /locus_tag="OPV72_002732"
     CDS             12596..13135
                     /locus_tag="OPV72_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2058 domain-containing protein"
                     /protein_id="HCR9914984.1"
                     /translation="MAKLTLQEQLLQAGLVTSKKMAKVQRTAKKSRVQAREAREAVEE
                     NKKAQLERDKQLSEQQKQAVLAKEFKAQVKQLIEMNRINVSKGDIGFNFTDNNVIKKI
                     DVDKLTQTQLINGRLAIARLVINNSGECEYAIIPASVADKIAQRDADSIVVNSALSQE
                     EQDEDDPYADFKVPDDLMW"
     gene            13182..14051
                     /gene="rluF"
                     /locus_tag="OPV72_002733"
     CDS             13182..14051
                     /gene="rluF"
                     /locus_tag="OPV72_002733"
                     /EC_number="5.4.99.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(2604) synthase RluF"
                     /protein_id="HCR9914985.1"
                     /translation="MLTDTSTRLNKYISESGICSRREADRFIEQGNVFINGKRAAIGD
                     QVVAGDVVKVNGRLIEPREADDLVLIALNKPVGIVSTTEDGERDNIVDFVNHSKRIFP
                     IGRLDKDSQGLIFLTNHGDLVNKILRAGNDHEKEYLVTVDKPITDEFIRGMGAGVPIL
                     GTVTKKCKVKKEAPFVFRITLVQGLNRQIRRMCEYFGYEVTKLERTRIMNVSLSGIPL
                     GEWRDLTDDELIDLFKLIEGSSSEAKPKAKAKPKTAGIKRPVVAIEKSNEKARPASSG
                     KRFTSPGRKKKGR"
     gene            complement(14048..14320)
                     /locus_tag="OPV72_002734"
     CDS             complement(14048..14320)
                     /locus_tag="OPV72_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3811 domain-containing protein"
                     /protein_id="HCR9914986.1"
                     /translation="MALPRITQKEMTEREQRELKTLLDRARIAHGRPLTNSETNSVKK
                     EYIDKLMALREAEAKKARQLKKKQAYKPDTEASFSWSANTPTRGRR"
     gene            complement(14383..15141)
                     /locus_tag="OPV72_002735"
     CDS             complement(14383..15141)
                     /locus_tag="OPV72_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCR9914987.1"
                     /translation="MNPIKRRKHILDELNKFGEVTVIKLSEMLNVTSETIRRDLSLLE
                     SEGKITKIHGGAVKKQVVQEDAFSARIEAHREEKIAIGKLAAEMISERDTLFIDSCTT
                     NLILAEQLPPLAFSVITNSALIADKIKEHNLQARVYVLGGEYDYHFRANLGVSVCQQI
                     NAIHADICFIGAGGISPQHGVLVKSFEEAYVAKAMIAMSKKSVILADHTKFGQDGVMC
                     IASVKEIDNIITDKGFTSTGYTPQDFAGKLRIAD"
BASE COUNT         3545 a         3948 c         4306 g         3484 t
ORIGIN      
        1 gttcgcattg gggatgtatc tggatcaaca acgaggagct gcatgatgaa tccacaggca
       61 accacaactg atgaattaac ctttaccagg ccgcaaggcg agctggaaaa gcaagtcctg
      121 accgctgagg cagtcgagtt tttgacggag ttagtcaccc gttttacgcc aaaacgcaat
      181 aaactcctgg ctgcacgtat ccagcaacag caggatattg ataacggtaa gttgcctgat
      241 tttatttcgg aaaccacttc cattagagaa agtaattggc agattcgtgg tattccggcg
      301 gatttacagg atcgccgagt agaaattacc gggccggttg aacgtaaaat ggtgattaat
      361 gccctgaacg caaatgtgaa agtgtttatg gcggattttg aagactcgct ggcgccggac
      421 tggaataaag ttattgatgg tcaaatcaac ctgcgtgatg cggtgaacgg caccattagc
      481 tataccaacg aagccggaaa aatctatcag ctcaagcccg atccggccgt attgatttgt
      541 cgtgtacgcg gtctacatct gccagaaaaa catgttacct ggcgggggga agccattccc
      601 ggcagcctgt ttgattttgc tctgtacttt ttccacaact acaaagcgct gctcgctaaa
      661 ggtagcggcc cgtattttta cctgccgaaa acgcaagcct ggcaggaggc agcctggtgg
      721 agtgaagttt tcagctacgc cgaagaccgc ttcaatctac cgcgcggtac gatcaaagcg
      781 accctgttga ttgaaacgct gcctgctgtt ttccagatgg atgagattct tcatgcgttg
      841 cgtgatcata tcgtcggtct caactgtggt cgctgggatt atattttcag ctatatcaaa
      901 acgttgaaaa atcacccgga tcgcgtcctg ccggacaggc aggtggtaac gatggacaaa
      961 ccgtttctga gtgcctactc gcgcctgctg atcaaaacct gtcacaagcg cggcgcgttc
     1021 gcgatgggcg gtatggcggc gtttatcccg agcaaagacg ttgaacgcaa taatcaggtc
     1081 cttgccaaag tgaaagcgga taaagcgctg gaagcgaaca acggccacga cggcacgtgg
     1141 attgcgcatc ccgggttggc ggatacggca atggccgtct ttaacgaggt actgggcgag
     1201 tacaaaaatc agctgttcat tacccgtgat gaagatgcgc cgattaccgc tgagcagtta
     1261 ctggagccat gtgaaggcga acgcacagaa gcgggaatgc gcgccaatat tcgcgtggca
     1321 gtgcagtaca ttgaagcgtg gatccccggc aatggctgtg taccgattta cggtctgatg
     1381 gaggatgccg cgacggcgga aatctcacga acctctatct ggcagtggat tcaccatgag
     1441 aaaacactga gcaatggaaa acccgtaacg aaagcgcttt tccgcgaaat gttggcggaa
     1501 gagatgcggg taatccagga cgaactgggc gagcaccgct acagcagcgg gcgcttcgac
     1561 gatgccgcac gtctgatgga gcaaatcacc acatcagatg acttaatcga cttcctcacc
     1621 ctgccgggct atcgcttact ggcttaattc accacataac aatatggagc atctgcacat
     1681 gaaaacccgt actcaacaaa tcgaagaatt acagaaagag tggacacaac cgcgctggga
     1741 aggcatcacc cgcccgtaca gcgcggagga ggtggtgaaa ttacgcggct cggttaaccc
     1801 ggaatgcacg ctggcgcagc tcggcgccgc gaaaatgtgg cggctgttgc acggtgaagc
     1861 gaaaaaaggc tatatcaaca gcctgggcgc gctgactggc ggtcaggcgc tgcagcaggc
     1921 gaaagccggt attgaggcga tttatctttc aggctggcag gtggtggcag atgccaacct
     1981 ggcatccagc atgtatccgg atcaatcgtt gtacccggca aactctgttc cggcggtagt
     2041 ggatcggatc aacaacactt tccgtcgtgc agatcagatc cagtgggcat ccggtattga
     2101 acccaacgat ccgcgctatg tggattactt cctgccgatc gttgctgatg cggaagccgg
     2161 ttttggcggc gttctgaatg ccttcgaact gatgaaatcg atgattgaag ccggtgcagc
     2221 ggccgttcac ttcgaagatc agctggcgtc ggtgaagaaa tgcggccata tgggcggcaa
     2281 ggtgctggtc cccacgcagg aggcgattca gaaactggtt gctgcgcgtc tggccgctga
     2341 tgtgatgggc gtcccgacgc tggtgattgc gcgtaccgat gcggatgcgg cagatctgat
     2401 cacctccgac tgcgatccct atgacagcgg ttttattacc ggcgaacgca ccagcgaagg
     2461 tttttaccgc acccatgcgg gcattgagca ggcgatcagc cgcggtctgg cgtatgcccc
     2521 gtatgccgat ctggtatggt gcgaaacttc tacgccggat ctcgaactgg cgcgtcgttt
     2581 tgccgatgct atccacgcga agtatccggg caaactgctg gcctataact gttcgccatc
     2641 cttcaactgg cagaagaatc tggacgacaa gaccattgcc agcttccagc agcagttgtc
     2701 ggacatgggt tacaaatacc agtttattac cctggcgggc atccacagca tgtggttcaa
     2761 catgttcgac ctggcgcatg catacgctca gggtgagggc atgaaacact atgttgagaa
     2821 ggttcaacaa cccgagttcg ccgcagcgaa agacggttac acctttgttt cccaccagca
     2881 ggaagtgggt actggttact tcgacaaagt caccaccatt attcagggcg gcgcgtcatc
     2941 cgttaccgcg ttaacgggtt ccaccgaaga atcgcagttt tgattgatgc ccggtggcgc
     3001 tgcgcttacc gggcctacag atagcgtagg ccggataagc gaacgcgcca tccggcatga
     3061 tgtggtgccg gatgagggaa aaaatgccgc gtggcctgga attactgatt gctcaaacca
     3121 tcctgcaagg ctttgacgcg cagtatggtc gatttctgga agtgacttcc ggcgcgcagc
     3181 agcgttttga acaggccgac tggcacgccg tccagcaggc gatgaaaagc cgtatccacc
     3241 tctatgatca tcatgtgggt ctggtggtgg agcaactgcg ctgtattacc gatggcaaaa
     3301 gtaccgacgc ggatttcctt ttacgcgtta aagagcatta cacccggctg ttgccggatt
     3361 acccgcgctt cgagattgcg gagagctttt tcaactccgt ttattgccgg ttatttgacc
     3421 accgctcgtt aacacccgag cggttgttta ttttcagttc gcaaccggag cgtcgcttcc
     3481 gtactatccc gcgcccgctg gccaaagact tctttcccga tcacggttgg gagccgctgt
     3541 tgatgcgcat actcagtgac ttaccgctgt gtctaccctg gcagaataaa agccgggata
     3601 tccgctatat tatcgcgcac ctgactgaaa cactgggcga ggacgcgcta cctcgctgcc
     3661 atgtccaggt ggcgaacgag ttgttttacc gtaataaagc ggcctggctg gtaggtaaat
     3721 taaccacacc tgacggtacg ctgccgtttt tattgccgat tcatcgcact gatgaggggg
     3781 aactgtttgt cgatacctgc ctgaccacca cggcagaagc gagcattgtg tttggttttg
     3841 cccgctctta ttttatggtg tatgcgccgc tgcctgccgc gctggttgag tggttgcgtg
     3901 aaatcctgcc gggtaaaacc actgccgaac tgtatatggc gattggctgc cagaaacatg
     3961 cgaaaaccga aagctaccgc gaatatttat gttatctggc tgaaagcgat gagaaattca
     4021 ttgaggcgcc tggaatccgc ggcatggtga tgctggtatt taccctgcca ggcttcgacc
     4081 gggtatttaa aatcattaaa gacaaattcg ccccgcagaa agagatgtct gccgcccatg
     4141 tgcgtgcctg ttatcaactg gtaaaagagc atgatcgcgt cggtcgtatg gcggataccc
     4201 aggagtttga gaatttcgta ctggataaac ggcaaatcga tccggcgctg atggcgctgt
     4261 tacgacaaga agcgccagag aagattaccg atcttgggga acatatcgtc attcgccatc
     4321 tctatattga acgtcgcatg gtgccgctca atatctggct ggaacaggta gaaggccagc
     4381 agttgcgcga tgcgatagaa gaatatggta atgcgattcg ccagcttgcc gccgctaata
     4441 ttttccccgg cgatatgttg tttaaaaact ttggcgttac ccgtcatggt cgcgtggtgt
     4501 tctacgacta cgatgaaatt tgctacatga cggaagtgaa tttccgcgat attccgccag
     4561 cgcgttatcc ggaagacgaa ctggccagcg aaccctggta tagcgtctcg ccgggtgatg
     4621 ttttcccgga ggagtttcgc cactggctgt gtgccgatcc gcgtatcggg ccattgtttg
     4681 aagagatgca tgccgacctg tttcgcgccg attactggcg cgcgctacag acgcgtatta
     4741 aagaagggca tgtagaagat gtgtatgcct atcgtcgccg ccagcgcttt agcgtgcgtt
     4801 atgaaaccga ccgtaggccg gataaggcct ttgcgccgcc atccggcaat gtacgccgtg
     4861 cctgatggcg ctgcgcttat caggcctaca aatcagttcc aacccttgct tatctaaacc
     4921 caccataggc cagcgtcacc tctttcgccg ctttaatcac catggcgcca agttcggtga
     4981 cgcgatcgtc ggtaatgcgt gagcaggggc cggaaataga gagggccgca aacggttcgc
     5041 ggtgttcgtc ataaatacac gaggccacgc agcgcagacc gagcgcatgt tcttcgtcgt
     5101 caaaggaata gccgcgcttg cgtgtttggg cgaggtcatc tttcagatgc agcggcgaca
     5161 ccagcgtcgc atgggtataa gcgtgcaacc ccttgcggtg cagcagactg gtaacctgtt
     5221 cctcactgag ctgtgataaa aacgccttgc ccgcgccaga ggcgtgcatg ggcagcttgc
     5281 cgccaatagg ggcggacatg cgcatcaatt gtgtgcactg cacctggtcg ataataatag
     5341 cctgatggtc gctctggtcg agtacggcaa ggtttaccgt ttcgccggag tcctccatca
     5401 gcttgcgcaa aatcggatgg acaatcgcca gcagattacg gctctgtaag aagctgctac
     5461 cgacgataaa cgcgtgtgcg cctacggccc agtggcccag ctcaccaacc tggcggacaa
     5521 aaccctgttg ctgcatggtg gtgagtagac ggtgagtcgt ggaattaggc aaacccgcct
     5581 gttgcgccag ttcggtcagc gcgacgctgc cgttggactc ggcaatccac tccagcagct
     5641 tcagaccgcg agttaaagac tgaacctgcc cggttacggg tgcagtggta gcggcaggtt
     5701 ttctcccgcg ttttgcggga acaggggcaa ccatggcaga ctcctttttc tgtatcgtgg
     5761 aaatcatttt cgttttattc aattataatg caagagttcc tgaactgatc ggatgagtga
     5821 catcacagga tgcccgatgg cgctgcgctt atcaggccta cgctttggga gccgccaaag
     5881 taatttgtag actgataagg cgcttgcgcc gccatccggc aaagcgacag aagtgggtgg
     5941 caagctgaac atgtctcatg ttgcccgttg ttctcttttc cgccagcacg ctttgtgcca
     6001 gtatggctcg ttacgtggag cgttgtcggg agcgagtgtg agcagcaaag ttgaacaact
     6061 gcgtgcgcag ttaaatgaac gtattctggt gctggacggc ggtatgggca ccatgatcca
     6121 gagctatcgt ctacatgaag aagatttccg cggggagcgc tttgccgact ggccctgcga
     6181 cctgaaaggc aacaatgacc tgctggtcct cagcaagccg gaggtgatcg ccgctatcca
     6241 caacgcctac tttgaggctg gcgcggatat catcgaaacc aacaccttta actcgacaac
     6301 cattgcgatg gcggattacc ggatggaatc cctgtcggcg gaaattaact atgcggcggc
     6361 caaactggcg cgcgcctgcg ccgatgaatg gacggcgcga acaccagaaa aaccacgctt
     6421 tgttgcgggc gtgcttggtc caactaaccg cacggcctcc atttcgccgg acgtcaacga
     6481 cccggcgttt cgtaatatca ccttcgatca gctggtggcg gcctaccgtg aatccaccaa
     6541 agcgctggtg gaaggcgggg cggacctgat cctgattgaa actgtcttcg acaccctcaa
     6601 cgccaaagcg gcggtgtttg cggtgaaaga agagtttgaa gcgctgggcg ttgatctgcc
     6661 gatcatgatt tccggcacca tcaccgacgc ctctggccgt acgctttccg gccagacgac
     6721 cgaagccttt tataactcgc tgcgccacgc cgaggcgctc acttttggcc ttaactgcgc
     6781 gctggggcca gatgaactgc gccagtacgt ccaggaactg tcgcggattg ccgaatgcta
     6841 cgtcaccgcg cacccgaacg ccggcctgcc gaacgctttc ggcgagtacg acctcgacgc
     6901 cgacaccatg gcgaaacaga ttcgcgaatg ggcggaagcg ggcttcctga atatcgttgg
     6961 cggctgctgc ggcaccacgc cggagcatat tgcggcgatg agccgcgccg ttgccggttt
     7021 gtcgccgcgc cagctgccgg atatcccggt ggcctgccgc ctttccggcc tggagccgct
     7081 gaacattggt gacgatagcc tgtttgtcaa cgtcggcgaa cgtactaacg tcaccggctc
     7141 ggccaaattt aaacgcttga tcaaagaaga gaaatacagc gaagcgctgg atgtcgcccg
     7201 tcagcaggtc gaaagcggcg cgcagattat tgatatcaat atggatgagg ggatgctcga
     7261 cgccgaagcg gcgatggtgc gtttcctcag cctgattgcc ggtgagccgg acattgcccg
     7321 tgtaccaatc atgattgact cctccaaatg ggaggttatc gaaaaagggc tgaagtgcat
     7381 tcagggtaaa ggcatcgtca actctatttc gatgaaagag ggcgtggaag cctttattca
     7441 tcatgcgaag ttgctacgtc gctacggcgc cgcagtggtg gtgatggctt ttgatgagca
     7501 ggggcaggcc gacacccgcg aacgtaaaat cgagatttgc cgccgcgctt acaaaatttt
     7561 gctcgaagag gtaggctttc cgccggaaga catcatcttc gacccgaata tcttcgccgt
     7621 cgccaccggt attgaagagc acaacaacta cgcgcaggac tttatcggcg cttgtgaaga
     7681 catcaaacgc gagctgccgc acgcgctgat ctccggcggc gtgtctaacg tgtccttctc
     7741 gtttcgcggc aacgacccgg tacgtgaggc tatccacgcg gtattcctct actacgccat
     7801 ccgcaacggc atggacatgg gcatcgtcaa cgccgggcaa ctggcgattt atgacaacct
     7861 gcctgccgaa ctgcgcgatg cagttgaaga tgtcattctt aaccgtcgcg atgacggcac
     7921 cgagcgtttg ctggatttgg cggagaaata tcgcggcagc aaaaccgacg aggctgccag
     7981 tgcccagcag gcggaatggc gtagctggga cgtgaaaaag cgtctcgaat actcgctggt
     8041 gaaaggcatt accgagttta tcgaacagga taccgaagaa gcccgtcagc aggccgcccg
     8101 cccgattgag gtgattgaag ggccgctgat ggacggcatg aacgtggtcg gcgacctgtt
     8161 cggcgaaggg aaaatgttcc tgccgcaggt ggtgaaatcc gctcgcgtga tgaaacaagc
     8221 ggtggcctac ctggagccgt ttattgaagc cagcaaagaa aaaggctcca gcaacggcaa
     8281 gatggtgatt gccaccgtga agggcgatgt gcacgacatt ggcaagaaca ttgtcggcgt
     8341 ggtgctgcaa tgcaacaact acgaaatcgt cgatcttggc gtgatggtgc cagcggagaa
     8401 aatcctcaga acggcgcgtg aagtgaatgc cgatctgatt ggtctttccg ggcttatcac
     8461 cccgtcgctg gacgaaatgg tcaacgtggc gaaagagatg gagcgtcagg gctttactat
     8521 cccgctactg atcggcggcg caaccacttc gaaagcgcat acggcggtga aaatcgagca
     8581 gaactacagc ggtccgacgg tctacgtgca gaatgcttcg cgtaccgtgg gcgtggtggc
     8641 ggcgctactc tccgacaccc agcgtgatga ctttgtcgcc cgtacccgca aagagtacga
     8701 aaccgtgcgt attcagcacg cccgcaaaaa accgcgcacg ccgccggtca cgctggaagc
     8761 ggcgcgcgat aatgatctgg catttgattg ggaacgctac accccgccgg tagcccaccg
     8821 tctgggcgtg caggaggtgg aagccagcat cgaaacgctg cgcaactaca tcgactggac
     8881 gccgttcttt atgacctggt cgctggccgg caaatacccg cgcattctgg aagatgaggt
     8941 ggtgggcgtt gaggcgcagc gtctgtttaa agacgccaat gatatgctgg ataaactgag
     9001 cgccgagaaa ctgttgaatc cgcgtggcgt ggtgggcctg ttcccggcga accgtgtggg
     9061 tgacgacatc gaaatctatc gcgacgaaac ccgtactcat gttctgacgg tcagccacca
     9121 cctgcgccag cagaccgaga aagttggttt tgctaactac tgtctggcgg attttgtcgc
     9181 gccgaaactg agcggcaaag cggactacat cggtgctttc gcggtgaccg gcggtctgaa
     9241 ggaggatgcg ctggcggacg ccttcgaagc gcaacacgac gactataaca agatcatggt
     9301 gaaagcgatt gccgaccgtc tggcggaagc gtttgccgag tatctgcatg agcgtgtacg
     9361 taaggtttac tggggatatg cgccgaacga gagcctgagt aacgacgaat taatccgcga
     9421 aaactaccag gggattcgcc cggcgccggg ttatcctgcc tgcccggaac ataccgaaaa
     9481 aggcactatc tggcagctac tggatgtcga aaaacacacc gggatgaagc tcaccgaatc
     9541 tttcgccatg tggcctggcg cgtcggtctc cggctggtac ttcagccatc ctgagagcaa
     9601 atacttcgcg gtagcgcaga tccaacgcga tcaggtgaca gattatgctt tccgtaaagg
     9661 aatgagcgtt gaggacgttg agcggtggct cgcgccgaac ctgggttacg atgcggactg
     9721 attcataaaa tcgtcacttt tccttacaac atacaaggca ctcattgggt gccttgtctc
     9781 tttcttacaa ttaaaccctt atactgaagg aaggctctac gctgaatttg ccggatggcg
     9841 gcgtaaacgc cttatccagc atgtatggta agcctggtgg cgtgcaacgc caccaggcct
     9901 taacgctgtg cgccatcagg caatttatcg caagtgagct tcaggaaaac gtataacgat
     9961 aaggagaacc tgacgccgtg ttaactttgc tccatctact ttctgccgtt gcgctgttgg
    10021 tatggggaac acatatcgtt cgtactggcg taatgcgcgt gtttggcgcg cgtctacgca
    10081 ctgtcctcag ccgcagcgtg gaaaagaaac cgctcgcctt ttgtgcgggt atcggtgtta
    10141 ccgcgctggt acaaagcagt aacgccacca ctttattggt aacgtcgttt gtcgcccagg
    10201 atcttgtcgc cctgacgcca gctctggtga ttgtgctggg cgccgatgtg ggtactgcgc
    10261 taatggcgcg tattctcacc tttgatttgt cgtggctatc gccgctgctg atttttattg
    10321 gcgtgatttt ctttttggga cgtaagcagt cccgcgccgg gcagctgggt cgcgtcggta
    10381 tcgggcttgg cctgattcta ctggcgctgg agctgattgt gcaggcagtg acgccgatca
    10441 ctcaagctaa tggcgtgcag gtcattttcg cgtcgctgac gggcgacatt atgctggatg
    10501 cgctgattgg cgcgatgttc gctattatca gttattccag cctggcggcg gtgttgctga
    10561 cggcgaccct gacggcggcg gggattatat cgttcccggt ggcgttgtgc ctggtcatcg
    10621 gcgccaatct gggatcgggc ctgttggcga tgctcaacaa cagcgccgcc aatgctgccg
    10681 cgcgtcgcgt agcgctcggc agcctattgt tcaaattgat cggcagcctg gtcatcctgc
    10741 cgtttgtcca tccgctggcg aatttgatgg atgagctacc gctaccgaaa tcagagctgg
    10801 tgatctattt ccacgttttc tataacctgg tgcgctgcct ggcgatggtg ccatttgccg
    10861 agctgatggc gcgtttttgt aaacgaatta ttcgtgatga gcctgaactg gatacccatc
    10921 tgaagccgaa acatctggat gtcagcgcgc tggatacgcc aacgctggcg ctggctaatg
    10981 ctgcccgtga ggtgttgcgc attggcgatg cgatggaaca gatgatggaa gggctaaaaa
    11041 aggtcatgca cggcgaaccg cgtgaagaga aagcgctgcg caagctggcg gatgacgtta
    11101 acgtgctcta caccgcgatt aagctttatc tggcgcgaat gccgaaagac gagctggcgg
    11161 cggaggagtc ccgccggtgg gcggagatta ttgagatggc cctgaacctc gaacaggcgt
    11221 cggatattat cgagcgaatg ggcagtgaga ttgccgacaa gtcgctggcg gcgcgtcggg
    11281 cattttcaga agaaggattg aaagagctgg atgcgcttta cgatcaactg ctcagtaatc
    11341 tgcaactggc gatgtcggtc tttttctccg gcgatgtcac cagcgcccgt cggttgcgcc
    11401 gcagtaaaca tcgcttccgt atacttaatc gccgatgctc acatgcgcat gtcgaccgcc
    11461 tgcaccagca gaacgtgcaa agtattgaaa ccagctcgct ccatttaggg ctgctgggcg
    11521 atatgaagcg tcttaactca ctgttctgtt cggtcgccta tagcgtactg gaacagccgg
    11581 atcaggacga ggaacggggc gagtattaag tgaaatgccg gatggcggtg taaacgtctt
    11641 ccggcctacg gaaaacatgc gcgtaggccc gccattcggc attcaatgtg gcctgggatt
    11701 aaaagcgatg acccgcttcc agcgccacgg cctcttcgcc cgctttaaac acccaggtgg
    11761 tattcgggcc gccgagaacc gcttggccgt tgctcacctg aatccagttg ccttccggca
    11821 aaccaatcac tgtcagttcc ggcgcgacca ccagcagttc gcgaatatgc tgctcgcggg
    11881 tctcgccctt atgaccctcc ggcaaggcgt tagtgaagtg aggattaatt tgcagcggga
    11941 acagatccag cgcgtcgaaa ccgtttggat cgacgatcgg catatcgttg gtcgtgcgga
    12001 tagtcgggca ggcaaggttg gcgcccgcgc tccagccgat atacagcgcg ccgcgtttta
    12061 ccctgtccgc caccggcgcc agcagcccgc gttcacgcga ttctttcagt agctggaagg
    12121 tatttccgcc gccgacaata acgatttccg ctttctcaat cgccgcaagc ggatcggcga
    12181 cacgatgaat ccctgtgacg tttatcccta atggcgcaag cacctctgcg gttttatccg
    12241 tgtactcgtc ccatgtttgc gtgacgccgg caaacggaat aaacacggct gagcgtcgac
    12301 cgttcaactg attcgctatc agcggcagag cgtgttccag ccaggcttta cccggcagcg
    12361 tcgagttact taataaaagc agttccatta tttctccacc tcatcaggaa atgtcaaaac
    12421 gtaataatgc taccattatc catttaatgt cttactgata tggctcatga tgttgcgcgt
    12481 gttacaggca acgcgcggtc gctaaaagtg acgccaggcc agatctgcca tctggtatcg
    12541 cctgaaaaat tacaggtata atccgcaaaa ttatttaaca cgtttagaga cgaaaatggc
    12601 aaaactgacc ttacaagagc aactgctaca agcgggatta gtgaccagca aaaaaatggc
    12661 caaagtccaa cgcacggcta aaaaatcacg cgttcaggct cgtgaggcca gagaagcggt
    12721 ggaagaaaat aaaaaggcgc aacttgagcg tgataaacaa ctcagtgaac agcaaaaaca
    12781 agcggtttta gcgaaagagt ttaaagctca ggttaagcaa cttattgaaa tgaatagaat
    12841 caatgtatct aaaggcgata ttggttttaa cttcaccgat aataacgtca tcaaaaaaat
    12901 agacgtggat aagcttaccc agacacaact gattaatggg cgtctcgcga ttgcgcgtct
    12961 ggttatcaat aacagcggtg aatgtgaata tgcgattatt cccgcgagcg tcgccgataa
    13021 aatcgcacaa cgagatgcgg acagtattgt cgtaaacagt gcgctgagtc aggaagagca
    13081 ggacgaagat gatccgtatg ccgattttaa agttcctgac gatttgatgt ggtaagtcac
    13141 attcccaacg tttatgtaga aaaatttctc agagagtaaa tatgctgacc gacacatcta
    13201 cccggcttaa taaatatatc agtgaaagcg gcatctgttc gcgtcgcgag gcggaccgtt
    13261 ttatcgaaca gggcaatgtc tttatcaacg gcaaacgcgc cgccattggc gatcaggtgg
    13321 tcgccgggga tgttgttaaa gtaaatggtc ggttgattga gccgcgagaa gcggatgatt
    13381 tagtgctgat tgcgctgaat aaaccggttg gcattgtcag taccactgaa gacggcgaac
    13441 gcgacaatat tgtcgatttt gtgaaccaca gcaaacgtat cttcccgatt ggtcgtctgg
    13501 ataaagactc gcaggggctg atatttctga ctaaccacgg cgatctggtc aataagattc
    13561 tgcgtgccgg taacgatcac gaaaaagagt atctggtgac ggtggataaa ccgattaccg
    13621 acgagtttat tcgcggtatg ggcgctggcg tgccgattct gggtaccgtc accaaaaaat
    13681 gtaaggtgaa aaaagaggcg ccgtttgtct ttcgcattac cctggtgcag ggattaaacc
    13741 gtcagatccg tcgtatgtgt gaatactttg gttatgaagt gacgaaactg gagcgtacgc
    13801 gcattatgaa cgtcagcctg agcgggattc cgctgggcga gtggcgcgat ctgacggacg
    13861 atgagctgat cgatctgttt aaattgattg agggttcctc ttccgaagcc aaaccaaagg
    13921 ccaaagcgaa gccgaagacc gcgggtatta agcgaccggt cgtggcgatc gaaaaaagca
    13981 atgagaaagc gcgcccggca tcaagcggta agcgctttac ctcaccggga cgaaagaaga
    14041 aaggacgtta acgtctgccg cgcgtcggcg tattcgccga ccaggagaat gacgcttccg
    14101 tatcgggttt atacgcctgc tttttcttca actggcgggc ttttttcgct tcagcctcac
    14161 gcagcgccat cagcttatcg atgtactcct tttttacgct gttggtctca gaattggtca
    14221 gcggacgccc gtgcgcaata cgggcgcggt ccagcaacgt tttcagttcg cgctgttcgc
    14281 gctcggtcat ctctttttgg gtaatgcggg ggagtgccat acgggtgccc tcagttagcc
    14341 gatgcattta gtctacggca atacgcaacg ggcggatagc gctcagtcag caatccgcag
    14401 ctttccagcg aaatcctgtg gcgtataacc cgttgacgta aatcctttat ccgtgatgat
    14461 gttatcgatt tcttttacgc ttgcgatgca catcacaccg tcctgaccaa atttggtatg
    14521 gtcagcgaga atcactgatt ttttgctcat cgcaatcatg gctttggcaa cgtaggcttc
    14581 ttcaaagctc ttcaccaaca cgccatgctg gggagaaatg ccgccagcgc caataaaaca
    14641 gatatccgcg tgaatcgcgt taatctgctg acataccgag acgccgagat tagcgcgaaa
    14701 atggtaatca tattcgccgc ctaatacata cacgcgggcc tgcaggttat gctctttaat
    14761 tttatcggca atcagtgctg aattggtaat cacggaaaaa gcgagaggcg gtaattgctc
    14821 ggccagaata aggttagttg tacaggaatc aataaacaat gtatcccgtt cactgatcat
    14881 ttcggcggca agtttgccaa tcgctatttt ctcttcgcga tgcgcctcta ttcttgcgct
    14941 aaacgcatct tcctggacaa cttgcttttt gaccgcgccc ccatgaatct tagtgatttt
    15001 gccttctgat tccagtaagg agagatcgcg acgaatggtt tccgaggtga cgttgagcat
    15061 ttccgataat ttaataacgg tgacttcacc gaatttgttt aattcatcaa gaatatgttt
    15121 tcgtctttta attggattca ttatctttcg ccgctgtcaa cctttggcgc atggtaactg
    15181 gatgcgtaag gcaacgcaac cactccaacg catggacgat accctcctca tcattcgtgg
    15241 cagtcacata gtcggcctgc cgctttactg catccggcgc gtt
//
LOCUS       DAJVBX010000105        15216 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.105, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000105 DAJVBX010000000
VERSION     DAJVBX010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 15216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15216
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.105"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(331..1206)
                     /locus_tag="OPV72_002736"
     CDS             complement(331..1206)
                     /locus_tag="OPV72_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HCR9914988.1"
                     /translation="MTSDKTLKQAISNITIWRKGEQRAPHKPLLLLYVLSHYRQGHDR
                     LFDYGSEIHEQLLDLLERYGPQRREQRPDMPFWRLKGDGFWELQNAEFCSTSGSRQPP
                     KRELIEYNVAGGFDAVNFALVTKKRKLIDTLAQQILEAHFPTSIQEDIADEMGFDIRT
                     SFRQRDPKFRQAVLRAYNYQCAVCGFNMRHDNAPIALEAAHIRWKQHHGPCEVPNGLA
                     LCAIHHKAFDRGSIGLDENMRVVVSDAVNGGGVVQRLFWDFAGKEIALPPVKENYPGE
                     RFVEWHRKEVFRGEH"
     gene            complement(1284..1523)
                     /locus_tag="OPV72_002737"
     CDS             complement(1284..1523)
                     /locus_tag="OPV72_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010989316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914989.1"
                     /translation="MVPAFFLPACLQRSDMELNNEYQNYEDEDDESADDLPPSHHPRS
                     FQSIIGWLYDKAVSGIAGIESAEMLAARYLEDAKG"
     gene            1787..5086
                     /locus_tag="OPV72_002738"
     CDS             1787..5086
                     /locus_tag="OPV72_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016505867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914990.1"
                     /translation="MSQSEYASILKCTPWLAKFLTRRGLKQPDHRPLYEYHATSEEYD
                     ELKRLLRAIGVPDGYKSDKGYAACFTLFCSEWYRRDYEREYGWAWEPIYKTIGISASS
                     SKMGKIIPKGLDGYWGRPVRFYDTERRNFLGSLFSEGGLPFRLLKESNSRFQSMFSLI
                     LNQYDQAKSSNISTFALVHAAVEKSSLPVVFKEDTSVELISRMAEQLVSLVQIYDLSN
                     HTEPVKELERVHPKWRDSFPVPLDDDTGTSFLNGLLRTASTESKPRLQKNKTTLCQFL
                     WSENHPEALQALISLPEELSFSIDIEPSTTRFELAIYEDGNEIASLGPAYATLSNSQA
                     KIKVRKREIKFYRRNPTVSLFIVARAGGMFFGSNLLEGSEVAVGDVPLVFVSDKNEWL
                     LQGQASCSVRGSHVLIVLPKDGCLASEHEDCDSGFSALGCHALTIKGRQDIIIKGDET
                     YRIKIGRDQIIHTGFSFQGKRLNWTSYPDELFLGVPGITQHSENLSTRHYKRFFNGTF
                     IENCDVQEKMGAQFISVRNENDETLLRKKIGILPNDFSLEIKNGQQANEGSVIITTQH
                     PCLYSLKEKTLEVGRKRLPDSTEIMMKAEGIPPASISLQITPNLTANPIVIWLPFPAR
                     GCLAFDKDEKPLPKNLTINDLLGARAYLFGKNGEPTRYQLELRLRSRSGMQAWYEWHY
                     SAGECPVELTLYSLREHIDNLLSLEEGIDQTVDMRIKGGGSSFTWQIRRYKYSLDYDR
                     GRQILLANSISNRTGQIPSPVIMLLSEPERKVVLLTSRMSEGVPVGEFELSSIIQKNG
                     PWLVLPKPGEEASFRPCFIAGEPVIQSDATAIQSLQKATQLFNPRSDVNTIMLVLEQM
                     ASDPAHSGWQFLRNLYDQFGYLPLATFEVWRALVQHPQALAMSLFKFEMSIDYLSRIE
                     SEFPVFWEFLSITEVKRSATRFRAFLTHKGAPEEMQIRLLYRMYQQLGTTFPTYASEV
                     QLWLSQGKLPPVFPELTMKGIILEWYQELLREHGESRWPEFGGPGLLRWYMSQQNPVI
                     DISPDASYRYSVTLLPVFAAAVASGKTTFESVFENKPGAVFFLRQVRDFDSRWFNAIF
                     QYCLLRNVTEK"
     gene            5099..7636
                     /locus_tag="OPV72_002739"
     CDS             5099..7636
                     /locus_tag="OPV72_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HCR9914991.1"
                     /translation="MTTRYFSSLIEQSLSRSTEATLSIMGVTNPNLREHLTQQMAADC
                     GKEGSFLASPVFEQTFGWKESNSTMKDLATKQTLLSKEVVDSLDSEENGRYRFGSDWK
                     PFTHQLASWQSLLEKKHSVVVTSGTGSGKTECFMVPVLEDLYRELQVKNKKPLIGVRA
                     LFLYPLNALINSQRERLDAWTRSFGSGIRYCLYNGNTEELHALVKSEQANRPNEVLSR
                     EKMREEPAPILVTNGTMLEYMMVRQVDAPIIQKSKAEKSLRWIVLDEAHTYVGSQAAE
                     LALQLRRVMTAFGVTPDDVRFVATSATIAGSDAEKQLKKFLSELSGVPQERIDVLGGS
                     RVIPELEPCKQYSLSLDEIEHIPDSESEGISPERYSALTHSPEARCLREMLVSQPRPM
                     KLDTLTQRLNELTKHQYTQQDVLRWIDLCSGTLPNAKDPAFLKVRAHIFQRNTQGIWT
                     CVDKNCAAKKNTALEKNWSFGNVYVNQRQNCECGSPVFELAFCNECNEPHLLARDKKG
                     KLVQWDNKGGDEFSLQDEISDDFETSGEKIQKDFVFQSPQIIAAECNTEAGYIMQRLD
                     RQTRSIGVVNPDSIPLAINDIEQICSASNCGYKGGKGKQPFRRALLGGPFYVTNIVPT
                     VLEYCQDFTSDEGKDGVGPLSLPGRGRRLITFTDSRQGTARMAVRMQQEAERSRLRGS
                     VVEILGWHQRKQPTSAPNDQADVMKLVARVTQYREEAREYREWGMPEEAKLSEAQAER
                     LEQAIQTATGGKAATILVCRTWTEMVNDLKEKADIQGPILQYNHYLKPEIFTENGGPL
                     KLAEMLLFREFMRRPKRTNSLETQGLVQVGYQGLEKAGSQCSYSLAG"
     gene            7674..11423
                     /locus_tag="OPV72_002740"
     CDS             7674..11423
                     /locus_tag="OPV72_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010989315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1998 domain-containing protein"
                     /protein_id="HCR9914992.1"
                     /translation="MTLDFYVRESNYIQLDDDLRNWIGSRFSSKFVRNPDSKEPDDNQ
                     VKRWPQIRHGNVTQRLVKLLILGAKFNTVNTVTIDIVNAWLKEAWLQLTGSLAVLKPD
                     GNRFYLPKEHLTFSLVQKARICPVTNKLLATTFKGLTPYLPMHIQFERLTSAQYDAFL
                     AQEVTLPAIWEHDRSQDDYVDGLTKVRDWVSQDPQVLPLRSQNLWTDINDRVVEGGFY
                     YRTAEHSAQQSSERLQSYERMFKNGQLNVLNCSTTMEMGVDIGGISAVVMNNVPPHPA
                     NYLQRAGRAGRSKESRAISYTLCKGNPHDQQVFANPLWPFETVIPAPMVAMNSERLVQ
                     RHVNSLLLSEYLCHVVGETEKERTSLNSQWFFGEELDQSVCNRFKAWLERPTLSIDNA
                     LERLVKGTALHGVTAEKLRDKTQEAIAVLQTRWLGIFRDLVKQESESQPNTPYRRRLE
                     LEKKRHCGEYLLRDLAARTFLPGYGFPTDVVTFDNFTMEDYIREKTHKSRDKNDREDN
                     VSRYKGLPSRNLSVAIREYAPGAEIILDGRVFRSAGVSLHWHNLNADTNEAQRLDSAW
                     RCHKCGTLGYEEGIGGSGDLFCTNSACGERITLDNRRQVLQPAGFVTDAHTPVTNNIE
                     TMKFIPVVPAWVFVKAERVPLPNPLMGFMASGADGHVFQQSMGEGGHGYALCLSCGRA
                     ESMLNATDTPKSMEAHYPPRPGKSDRDSQNQRIICPGSTALNKNVTLGALARTDVFEL
                     ILRRPQNGEYIPDNSDEGRIVAMTLAVALRRALASVLGVSATELGYAVRPVRLDNEQS
                     VLAVQLYDIISGGAGFASSAPLHIEAVLKGMVKQLGCRHCDTACSECLLDSQTRHDHD
                     QLDRKAAQAWLGEDFSHYIGLPEAEKFSLADAQYCPGSIEDAIRRAINDGARKLTLWM
                     NGPLNEWDLYARQFRTAIQNYRLKDEVEVTLVVPGHIEDPELLQEIAQFAAIGMQLCQ
                     SELNTDTPVVAQVAFNDRLMMLISRSPEATIPGPNWHLNSQMVIRSHAFEPITLSKAE
                     LLSDAAGSRGLVNDIEIHKQLNGPVSQFGQRFWGVLTGAQEDIQTLLKENQVTRIHYS
                     DRYLQNPVALALLGGLLKPLKSILAQDAQVTIDTLFKSKERPGNKPFHDWMSEADFQD
                     FADQWFAASMGRAVVVNTVGSPRDIPHHRKLMVTFSNGQALKIRFDQGMGYWRIVFAR
                     AYRDFDFNDDVAFQLGNMAKACVEGQVVNSEESWATDVLVQVIVP"
     gene            complement(11534..12368)
                     /locus_tag="OPV72_002741"
                     /pseudo
     CDS             complement(11534..12368)
                     /locus_tag="OPV72_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611505.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(12631..13476)
                     /locus_tag="OPV72_002742"
     CDS             complement(12631..13476)
                     /locus_tag="OPV72_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000490324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiK family protein"
                     /protein_id="HCR9914993.1"
                     /translation="MFRYLCNQKAALLTAILLMAAGVLTLCFPESWYPQETEWQLTAE
                     KEITGIHGGLSGLTWNPDSRTLFAVTDHPSSVVELDTEGNVLRVIPSDGDHDFEAIEY
                     LGGNRYALSRERERTLTTHCIDSSTTVLPPATYSLTLDVNRHSDNAGFEGLAWGRGEH
                     ALMVAQEKKPLRLYVTDRSPDALSVSDSLTHRASLPWFLKDISGLHYDRNNGLLYVLS
                     HESAVVVVSDLDGGRKVMSLRRGHCGLRRDIPQAEGIASDDRDTLWIVSEPNLFYRFT
                     RTASS"
     gene            complement(13527..13673)
                     /locus_tag="OPV72_002743"
     CDS             complement(13527..13673)
                     /locus_tag="OPV72_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914994.1"
                     /translation="MPTDDKGTIQAGDIPPLRALILLLLTSVFISGFLTGVLAMLWLI
                     CRGA"
     gene            complement(13663..14199)
                     /locus_tag="OPV72_002744"
     CDS             complement(13663..14199)
                     /locus_tag="OPV72_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HCR9914995.1"
                     /translation="MADAPAEVELFFFYCPPCYAFSQTMGVARAIRHVLPHGDRMIKY
                     HVSLLGPLGHELTQAWALAMMMKETDVVEKAFFTADMVEKRLHSPDDVRRVFMSATGI
                     SRGEYDRSIKSPAVNDMVALQERLFKEYGVRGTPSVYVRGRYHINNAAFGAFSVEDFR
                     SRYAAVVRKLLAGNPDAD"
     gene            complement(14562..14912)
                     /locus_tag="OPV72_002745"
     CDS             complement(14562..14912)
                     /locus_tag="OPV72_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCR9914996.1"
                     /translation="MASALTAFPEDGDISRIWYDRLCIEFNSDGGLSPAELRVIRLLL
                     QGYNCGQIAALCFRSVKTISAQKGLAFRRLGVRNDATLLPTLMLLGMVTLYTDLNRCH
                     SLEESGPECGSEAG"
     gene            complement(14897..15106)
                     /gene="pefI"
                     /locus_tag="OPV72_002746"
     CDS             complement(14897..15106)
                     /gene="pefI"
                     /locus_tag="OPV72_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator PefI"
                     /protein_id="HCR9914997.1"
                     /translation="MGESIITNIISIIRERQSTDNAPVKIRDIADAAGLSIYQVRSYL
                     EQLRAVGVLEKVNAGKGAPGLWRLL"
BASE COUNT         3882 a         3747 c         3873 g         3714 t
ORIGIN      
        1 taccggtttt gatatggtgt tgaatcctta tataaaacat gaggtaattc tcatgcttca
       61 tacgacgaat cccgtcagca agataagcaa aagccagcaa tatcgggcta cttacaatct
      121 ccctgtgctc tttaagatgc cgcgcctcat aaattccgct tgcgctcatg atggctcatc
      181 tggcgctcta cgcgtcgcct gactacaggt gtgactccac cagcgcgcta cagaccatag
      241 tgcgagaacc gtggccgatt acttcgatgc ttttgatgtg gagctatttt taacagataa
      301 cgtataccac actcaaaata ctcccccaga tcaatgctct cctctgaaca cctctttcct
      361 atgccattcc acaaaccgct cacccggata attttcttta accgggggca acgcgatctc
      421 tttccccgca aaatcccaga acaaccgctg taccactccg ccaccattca ccgcgtcgga
      481 aaccactacg cgcatatttt catccaggcc aatcgaacca cgatcgaacg ctttatgatg
      541 gattgcgcac aacgccaggc cattaggtac ttcacaagga ccatgatgct gcttccatct
      601 gatatgggct gcttcaaggg ctataggggc gttgtcgtgg cgcatattga agccgcagac
      661 cgcacattga taattgtaag ctcgtagcac cgcctggcga aacttcggat cgcgttgacg
      721 gaaagaggtg cgaatatcaa aacccatctc gtcagcgatg tcttcctgaa tactggtcgg
      781 aaaatgcgcc tcaaggatct gctgcgccag cgtgtcgatt agcttacgtt tttttgttac
      841 cagcgcgaaa ttgacggcat caaacccacc agcaacatta tattcaatga gttcacgttt
      901 aggtggctgg cggctaccgc tggttgagca gaattccgcg ttttgcaatt cccagaaacc
      961 atcgcccttc agacgccaga acggcatatc cgggcgctgt tcacggcgct gtggcccata
     1021 gcgctccagc aaatccagca attgctcatg aatttcagaa ccataatcaa acagacgatc
     1081 gtgaccctgc cgatagtgcg agagaacata taacagcaat aacggcttat gcggcgctcg
     1141 ctgttcgcct ttgcgccaaa tagtaatatt tgatatcgct tgctttaggg ttttgtcaga
     1201 ggtcattaca ttgaagaatt catgagcaca tagttgcgat gatgctctcc cagtggatca
     1261 tggtgcgggc ggcgagctgt gcatcaccct ttcgcgtcct caagataacg ggcggcaagc
     1321 atttcagcgg attcgatgcc tgcgatacca ctgactgctt tgtcgtagag ccaaccgatg
     1381 atggactgga aagagcgcgg gtggtgggat ggagggaggt cgtcagcgct ttcgtcgtcc
     1441 tcgtcttcgt agttttggta ttcgttattc agctccatat cactcctttg taggcaggca
     1501 ggtaaaaaga aggccggaac catcgtaaag acggttccgg ccggaggttc aatgggatga
     1561 tatggggttg aaaagatttg tagctacaaa tcatctcctt acagattaaa acaaatggcg
     1621 agtagcccct ccgtataata aacttaactt attgattaaa atcaaactaa tatcaatttc
     1681 aaatttaatt aaattcataa ttcaattatt gttatctgtt ttttcaaaat aacaaaaagt
     1741 tataataact ttcagccatt cactgttcta atgcaaggag cttgctttga gtcagtccga
     1801 atacgcatcc attctaaagt gtaccccatg gctagctaaa ttcctcaccc gcagaggatt
     1861 gaagcaacca gaccatcgtc cgttatatga ataccacgca acgagtgaag aatatgatga
     1921 attgaaacgg ctgctgcgag ctataggggt acccgatggt tataaaagtg ataaagggta
     1981 cgcagcctgt ttcacattgt tctgctcaga gtggtatcga agagattatg aaagagagta
     2041 tggatgggca tgggagccaa tttacaagac gataggtatc tcagcatctt cctcgaaaat
     2101 ggggaaaatt atccctaaag gcctggatgg ttactggggg cgtccagtgc ggttttatga
     2161 cacagaaagg cggaatttct taggctcctt attcagtgaa ggcggtctac ctttcaggtt
     2221 gctaaaggaa tctaatagcc gttttcagtc gatgttttct ctcattctaa atcaatacga
     2281 tcaggctaaa tcttctaaca tttccacgtt cgcgttagtc catgcagcgg tagaaaaatc
     2341 atccctgcca gtcgttttca aagaggatac ttcagttgag cttattagtc ggatggctga
     2401 acagttagta tctcttgttc aaatttatga tttaagtaat cataccgaac ccgtaaaaga
     2461 acttgaacgt gttcatccta agtggcgtga cagtttccct gtccctctcg atgatgatac
     2521 gggtaccagt ttccttaatg gacttttacg aacagcttct actgaatcaa aaccccgcct
     2581 tcaaaagaat aaaaccactc tctgtcagtt tttatggtca gaaaatcatc ctgaagccct
     2641 ccaggcactc atttctctgc ctgaagaact gagtttttca attgatattg agccttcaac
     2701 aacgcgcttc gagcttgcta tctatgaaga tggtaacgaa atcgcaagtc tgggacctgc
     2761 atatgcaacg ctaagtaact cccaggcaaa aataaaagtt cgtaagcgcg agattaaatt
     2821 ttaccgaaga aatcccacgg tcagtttgtt tattgtggcg agagctgggg gtatgttttt
     2881 cggctccaat cttttagaag gcagtgaagt tgcggttggc gatgttccat tggtttttgt
     2941 ttctgataaa aatgaatggc tgttacaggg acaagcctct tgcagcgtac gtggcagcca
     3001 tgtacttatt gtgctgccaa aggatggctg tctggcttca gaacatgagg attgtgactc
     3061 tggcttttcg gctttgggat gccatgctct gaccatcaaa ggtcgccagg atatcatcat
     3121 taaaggcgat gaaacgtacc ggataaagat aggaagagat cagattatcc atactggatt
     3181 ctctttccag gggaagcgat taaattggac aagttatccg gatgaactct tcctcggtgt
     3241 tcctggaatt actcaacatt ctgagaatct atcaacgcgc cattacaagc gttttttcaa
     3301 cggaacattt atagaaaatt gtgatgtaca agaaaaaatg ggagcacagt ttatttcggt
     3361 gcgtaacgaa aatgatgaaa cgttactgcg taagaaaatt ggcattctcc ccaatgattt
     3421 tagtctggaa ataaaaaatg gacaacaggc gaacgaaggt tctgtcatta ttactactca
     3481 gcacccttgt ttgtatagct tgaaggaaaa aacacttgaa gttggacgga agcggttgcc
     3541 cgatagtaca gaaataatga tgaaggcgga gggcattcct cctgcatcaa tttcattaca
     3601 aataacgcca aacctcactg caaacccgat tgttatttgg ttaccatttc ctgcacgagg
     3661 ctgtcttgcg ttcgataaag atgagaaacc tctcccgaaa aatttaacga ttaacgatct
     3721 tctgggtgcc agagcatatc ttttcggaaa aaatggtgag cctacgcgat accagcttga
     3781 actacgttta cgttcgcgta gtggaatgca ggcctggtat gagtggcact acagtgcggg
     3841 agaatgtccg gtagagctta ctttatatag cttaagggaa catattgata atttactctc
     3901 cctggaggaa ggaattgatc aaacagttga tatgcgcata aaaggaggtg gtagttcttt
     3961 tacctggcag atccgacgtt ataaatatag tctggactat gatcgtggca ggcagattct
     4021 tctcgcaaac tcaataagta atcgtacagg ccagatccct tcgcccgtca ttatgttact
     4081 cagcgaaccg gagagaaaag ttgtactgct gacgtcaaga atgagcgaag gtgtaccagt
     4141 tggtgaattt gaactaagtt cgataataca aaagaatggc ccatggctgg tgctgccgaa
     4201 accaggtgaa gaagcctcat ttcgaccttg ctttattgca ggtgagccgg taattcaaag
     4261 cgacgcgaca gcaatacagt ctttacaaaa agcaacgcag ctttttaatc ctcgttcaga
     4321 tgtcaacacc attatgttag ttctggaaca aatggcgagc gacccggcac actcgggctg
     4381 gcagttctta cgcaatttat acgatcagtt cgggtattta cctttggcta cctttgaagt
     4441 atggcgggca cttgttcagc atccacaagc gttggcgatg tcgctgttca aatttgaaat
     4501 gtccattgat tatctcagcc gtattgaaag tgagtttccc gttttctggg agtttttatc
     4561 cattacagaa gttaaacgtt ccgccacacg ttttcgtgct tttttgactc ataaaggtgc
     4621 accggaggaa atgcagataa ggttgctgta cagaatgtat caacagctgg gcacaacatt
     4681 cccgacttat gccagtgagg tgcaattatg gttgagtcaa gggaaattac caccggtttt
     4741 tcctgagttg acgatgaaag gtattatcct tgagtggtat caggaacttc tacgcgaaca
     4801 tggtgaatct cgctggccag aatttggtgg cccaggcctt ttacgttggt atatgtcgca
     4861 acaaaatcct gttatcgata tttcccctga tgccagctac cgctattccg tcaccttgct
     4921 ccccgtattt gctgctgctg ttgccagcgg taaaacaaca tttgaaagtg tttttgagaa
     4981 taagcccggc gccgtatttt tcttgagaca ggttagagat tttgactcac gatggtttaa
     5041 cgccattttc caatactgtc tattgcgtaa tgttactgaa aaataaaaag gaataagaat
     5101 gactacacgc tatttttctt cgctgattga acaatcactg tcgcgttcta cggaggcgac
     5161 gctgagtatt atgggggtga ccaacccgaa tcttcgcgag catctcacgc aacaaatggc
     5221 ggccgattgc gggaaagaag gatcgtttct tgcctccccc gtatttgaac agacatttgg
     5281 ctggaaagag tccaacagca caatgaaaga ccttgcaaca aaacaaacgt tgctaagcaa
     5341 ggaggtggtg gactcgctgg atagtgagga aaatggtcgt tatcgttttg gctctgactg
     5401 gaaacctttc acgcatcagt tagccagctg gcaatcatta cttgagaaaa aacactcagt
     5461 cgtggtgacc agcgggacag gctctggcaa aacggaatgc tttatggtcc cggtactgga
     5521 agacctctat cgtgagcttc aggtcaagaa caaaaaaccg ttgataggtg tgagagcact
     5581 ttttctttac ccactgaatg ccctgattaa ttcccagcgc gagcgtttag atgcgtggac
     5641 ccgtagtttt ggttccggaa ttcggtactg tctgtataac ggtaacacag aagaattgca
     5701 cgctttggtc aaaagtgagc aggcaaacag gcctaatgag gttttgtcac gagagaagat
     5761 gcgtgaagaa cccgccccca ttttagtgac caacggtacc atgctggaat acatgatggt
     5821 tcgtcaggtt gatgcaccga ttattcagaa atcaaaagct gaaaaatcat tacgctggat
     5881 agttctggat gaagcccata cctacgttgg ttctcaggcc gctgagttgg ctctacagct
     5941 ccgtcgcgtc atgacggcat ttggcgtcac gcctgatgat gttcgctttg tggcgacgtc
     6001 ggccaccatt gccggaagtg atgctgaaaa gcagctgaaa aaattcttgt ctgagctgtc
     6061 aggagtgcca caggaacgta ttgatgttct gggcggaagc cgcgttattc ctgagctcga
     6121 accctgcaaa caatattctc tgtcactgga tgagattgag catatccctg attcggagag
     6181 tgaagggatc agtccggagc gttatagtgc gttgacccac tctccggaag cgcgctgttt
     6241 acgcgaaatg ctggttagcc aaccccgacc aatgaaactt gatacgctga cccagcgttt
     6301 gaacgagctg accaaacatc agtacacgca gcaggatgtt ttacgctgga tcgatctttg
     6361 ctctggcaca ctccctaatg caaaggatcc tgcatttctg aaagtcagag cacatatttt
     6421 ccagcgaaac acccagggca tctggacatg tgtggataag aactgtgcag ctaaaaaaaa
     6481 taccgcgctg gaaaaaaact ggtcttttgg caatgtgtat gtaaatcagc ggcaaaactg
     6541 cgagtgcggc agtcccgttt ttgaactggc attctgcaat gagtgtaatg aaccgcatct
     6601 tcttgcacgg gataaaaaag gcaaactcgt acagtgggat aataaaggtg gagatgaatt
     6661 ctccctacag gatgaaattt ctgacgattt tgaaacatcc ggagaaaaga ttcagaagga
     6721 ttttgtattc cagtcgccac aaattattgc tgcggaatgt aatacggaag ctggctatat
     6781 tatgcagcgg ctcgatcgtc agacccgcag tatcggcgtg gtgaacccgg acagtattcc
     6841 gctggcaatt aatgatatcg aacaaatctg tagtgccagc aattgtggct ataaaggcgg
     6901 aaagggtaaa cagcccttcc gaagggcgtt actgggcggg cctttttatg tcaccaatat
     6961 tgtgcctacg gtgctggagt attgtcagga cttcactagt gatgaaggta aagatggtgt
     7021 cggcccgctc tctttgcctg gtcgaggtcg tcgcctgatt acctttaccg acagtcgtca
     7081 ggggacggcg cgaatggcag tacgtatgca gcaggaagca gagcgcagcc gattacgtgg
     7141 tagcgtagta gaaattcttg gctggcacca acgaaaacag ccaacgagtg ctccgaatga
     7201 ccaggctgac gtgatgaaac tggttgcaag ggtgacacaa taccgtgaag aagcccggga
     7261 gtatcgcgag tggggaatgc ccgaggaagc aaaactttct gaagctcagg ccgaacgcct
     7321 tgaacaggca atccagacgg cgacgggggg aaaggctgca accattttag tttgccgaac
     7381 ctggacggaa atggtcaatg atctgaaaga gaaagccgat atacagggac caattttaca
     7441 atataaccat tatctgaagc ctgaaatttt caccgaaaat ggcggccctt tgaaactcgc
     7501 cgaaatgctg cttttccgtg agtttatgcg acgcccgaaa cgaaccaaca gcctggaaac
     7561 ccaggggctg gttcaggttg gctatcaggg gctggagaag gcaggctcac agtgttccta
     7621 ctcactggca ggctaaaggc ttaacccttg atgactggcg cgattttctg aaggtgacgc
     7681 tggatttcta tgtcagagaa agcaactaca tccaactgga tgacgatcta agaaactgga
     7741 tcggtagccg tttctcttcc aaatttgtcc gcaacccaga ttcgaaagag ccagatgaca
     7801 accaggttaa acgctggccg caaattcgcc acggtaatgt gactcagcgc ctggtcaagc
     7861 tgttgatttt aggggccaaa tttaacaccg taaatacggt aactattgat attgttaacg
     7921 cctggctgaa agaagcctgg ctccagctaa caggatctct ggcggtattg aagcctgatg
     7981 gaaaccgttt ttatttaccg aaagagcatc tgacattctc tctggtgcaa aaagcacgca
     8041 tttgtccagt gaccaataaa ttactggcga caaccttcaa aggtctgacc ccctatttgc
     8101 ccatgcatat ccagttcgag cgactgacga gtgcacagta cgacgcgttt ttggctcagg
     8161 aagtcacgct gccagcgatc tgggaacacg atcgctctca ggatgattat gtcgacgggt
     8221 taacaaaagt gcgtgactgg gtaagccagg atccgcaagt gctaccatta cgctcgcaaa
     8281 acctctggac ggacattaac gatcgcgtgg tagaaggtgg attttactac cgcaccgcag
     8341 aacactcggc acagcaatcg tcggagcgcc tgcaaagcta cgaaagaatg tttaaaaacg
     8401 ggcagcttaa cgtccttaac tgctcaacca cgatggaaat gggtgtggat attggcggta
     8461 tttctgcagt ggtgatgaac aacgttcctc cgcatccggc caactattta cagcgagccg
     8521 ggcgtgccgg gcgtagtaaa gagtcacgcg ctatttcgta caccttgtgc aaagggaacc
     8581 cgcacgatca gcaggttttt gctaatcccc tctggccgtt tgagacggtg atcccggctc
     8641 caatggtggc aatgaactca gagcgtctgg tgcagcgtca cgtcaattcc ctgttactgt
     8701 cagaatactt atgccatgtg gtcggtgaaa ccgaaaaaga gcgtaccagc cttaatagcc
     8761 agtggttctt tggcgaagag ctcgaccagt cggtatgcaa tcgttttaaa gcctggctcg
     8821 aacgtccgac gctgagcatt gataacgcgc tggagcgtct ggttaaaggg acggcattgc
     8881 acggcgttac ggcagaaaaa ctgcgggata aaacgcagga ggctattgcc gtcttacaga
     8941 cacgctggct ggggatcttc cgcgatctcg tgaaacagga aagtgaatcg cagcccaata
     9001 cgccgtaccg caggcgactg gaactggaga aaaaacggca ttgtggtgaa tacctgttac
     9061 gcgatctggc ggcccgaact ttcctacccg gatatggctt cccaacggat gttgtcactt
     9121 ttgataactt caccatggaa gattatatcc gcgagaaaac gcacaaaagc cgtgataaga
     9181 atgaccggga ggataacgtt tcgcgttata aagggctgcc ttcgcgcaac ctttccgttg
     9241 cgatccgtga gtatgcgccg ggcgcggaga ttatccttga tggtcgggta ttccgctcgg
     9301 ccggtgtttc gctgcactgg cataacctta acgccgatac taacgaagcc cagcgtctgg
     9361 acagcgcctg gcgttgccat aaatgcggta ctttaggcta tgaggaaggt attggtggct
     9421 cgggggattt attctgtacc aatagcgcgt gcggggagcg gatcacgctg gataaccgac
     9481 gtcaggtatt acagcccgcc ggttttgtca ccgatgccca tactcccgtt acgaacaaca
     9541 ttgaaacaat gaaattcatc ccggtggtgc ctgcctgggt gtttgtgaaa gcagaacgcg
     9601 tgccactgcc aaacccgctg atgggtttta tggcgtcagg cgcggatggt catgttttcc
     9661 agcagagcat gggcgaaggt ggacacggtt atgcgctgtg cctgagctgc ggccgggcgg
     9721 agtcaatgct caatgccacc gatacgccga aatcgatgga agcgcattat cctccgcgcc
     9781 ccggtaaatc tgatcgcgac agccagaatc agcggattat ctgccctggc tccacggcgc
     9841 tgaataagaa tgtcacgctg ggtgcgctgg cgcgcaccga tgtgtttgaa ctcattttgc
     9901 gccgtccgca aaacggggag tatatccccg ataattctga tgaaggccgt attgtggcca
     9961 tgacgctggc ggttgcacta cgtcgagcgc tggccagcgt gctgggggta tcggcgacag
    10021 aactgggcta tgcggtgcgt ccggtcagac tggataatga gcaatcggtc ctggcggtgc
    10081 agctttacga cattatcagc ggcggtgcgg ggtttgcttc cagtgcgcca ttgcatattg
    10141 aagcggtcct caaagggatg gtgaaacagc tgggatgccg ccactgtgat accgcctgta
    10201 gcgaatgtct gctcgattcg cagacccgcc acgatcacga tcagctggat cgtaaagccg
    10261 cgcaggcctg gctgggggag gatttcagtc actatatcgg tttgccggag gcggaaaaat
    10321 tctccctggc cgacgcgcag tattgcccag gcagcattga ggatgctatc cgtcgtgcca
    10381 ttaacgacgg ggcgcgcaaa ctcacgttgt ggatgaatgg gccgcttaac gagtgggatt
    10441 tgtatgcccg ccagttccga acggcgatcc agaactatcg gctgaaagat gaggttgagg
    10501 ttacgctggt tgtgcccggt catattgaag atccggagct tttacaggag attgcgcagt
    10561 ttgccgccat tggtatgcag ctttgccagt ctgagctgaa tacggatacg ccggttgtcg
    10621 cacaggtagc attcaacgat cgcctgatga tgttgatttc tcgcagccca gaggccacca
    10681 tccccggccc gaactggcat ctgaatagcc agatggttat tcgcagccat gcgtttgagc
    10741 cgataacgct tagtaaagca gagctattat ccgatgccgc aggtagcaga ggcctggtca
    10801 acgatattga gatccataag cagcttaatg gcccggtttc tcaatttggt cagcgtttct
    10861 ggggcgtgtt aaccggggcg caggaagata ttcagacgct gctgaaggaa aaccaggtga
    10921 cgcgcattca ctatagcgat cgttatctgc aaaacccggt ggcgctggcg ttattaggcg
    10981 ggctgttaaa accgctgaaa tcgatcctgg cgcaggatgc gcaagtgacg attgatacgc
    11041 tgtttaagag taaagagcgg ccaggcaaca agccgttcca tgactggatg agtgaagcgg
    11101 attttcagga ttttgccgac cagtggtttg cggcatctat gggcagagcc gtcgtggtta
    11161 acaccgttgg ctcgccgcgt gatattccac accatcgtaa actgatggtg accttcagta
    11221 atggtcaggc gctgaagatc cgttttgacc aagggatggg atactggcgc atcgtctttg
    11281 cgcgagcgta tcgcgatttt gattttaacg atgatgtggc tttccagctc gggaatatgg
    11341 caaaagcctg cgttgaaggt caggtggtca acagcgagga aagttgggca accgatgtgc
    11401 tggtgcaggt gatagtccct taatgcgaaa ccgctcccga ttaaacatcg ggagcggcta
    11461 acatcaggcg gtggtgcgct tgccggtaat catgtcgata atgaccctgg cacaaattca
    11521 gtacagtgct aaatcagaga gcttcgtctt tccggagact tcggataaat tcagccggag
    11581 tcatgtcatt taatgatgaa tgcgttctct catgattgta ttccctgcgc cagttgtcgg
    11641 gtttttcctg cgcatcttcc agtgacagga accagtgaat gttcaggcat tcatcccgca
    11701 gactgccgtt aaatggttca ataaacgggt tatctgtcgg ctttccgggg cgcgagaagt
    11761 ccattgtgac gccgtgttca tacgcccatt tatccagact ttttgagata aactcgctgc
    11821 cgttatccgt ctggattcgt accggcagcc gcttatccgg cacccgcagt gcctccatta
    11881 ttctgaccac atcctcgcct tttaacgatt ttccggcatg gatcgccagg cattcccgac
    11941 taaaattatc cactacagcc agcgcccgaa aacgccgccc gttaaacaga ttatctgaca
    12001 caaaatccat actccggcac tgatcgacat gcgtcagaac cgggcgctga tacagtaagc
    12061 ctcccgcaaa aatgtaaccg cctggcgctt ctgagccggc ctcagaactt ttgcttcagt
    12121 acctcctgca gcatctcctt gtcgagactc agctcagcga ccagcttctt cagccgctga
    12181 ttctcatcct ccagttgccg cagacgccgc tgttccgtca cgcccggccc ggcaaatttt
    12241 ttcttccagt tgtaaaatgt ggcctcagaa attcccatct ttctgcagac ttccccgacg
    12301 cgggtgccgg tttcagcctg tttcagggca aatgcagtct gttcttcggt ataacgggtc
    12361 tttttcatgg caatgcgcct ctctgtgaga tggaagaaag accggaaact tcagtttaga
    12421 ctggcactgt ttacaggggg aaggtcaggg gaaggtcatc aaccagcttc ccaccatcac
    12481 cacaaaccag aataattccc tgaaaaaaga tgcgctgaat gttatgtttt tcatcatctt
    12541 tccactgtca gaatccaccg ctgacaccgg caccaacacc ggtcggcttc acgcggcgaa
    12601 ttttacttca ccttccgcgc cgcctcatcc tcaggacgaa gccgtgcggg tgaagcggta
    12661 aaacagattc ggttcactga ctatccacag cgtgtcccgg tcatctgagg ctatcccctc
    12721 cgcctgcggg atatcccttc gcaggccaca gtgtccccgg cgcagcgaca tcaccttcct
    12781 cccgccgtcc agatccgaca ccacgaccac ggcagattca tgggaaagta catacaggag
    12841 cccgttgttc cggtcataat gcagaccgga gatatccttc aggaaccatg gcagggacgc
    12901 ccggtgtgtc agcgagtcac tcaccgacag cgcatcaggg ctccggtccg tcacgtaaag
    12961 ccgcagcggt tttttctcct gcgccaccat cagggcatgc tctccccgtc cccaggcaag
    13021 gccttcaaaa ccggcattgt cgctgtgcct gttcacatcc agcgtcaggc tgtatgttgc
    13081 cggcgggagg acggtcgtgc tgctgtcaat gcagtgggtg gtgagcgtcc gctcccgctc
    13141 ccgggacagg gcatagcggt tcccgccgag gtattcgatg gcctcaaaat cgtggtcgcc
    13201 gtctgacggt atcacccgca gcacgttccc ttccgtgtcc agctccacca ccgaggaggg
    13261 gtggtcggtc acggcaaaca gcgttctgct gtccgggttc catgtcaggc cggagaggcc
    13321 gccgtgtatc ccggtaattt ctttttctgc cgtgagctgc cattctgttt cctgcgggta
    13381 ccaggactcc gggaaacaca gggtgagcac gccggccgcc atcaggagaa tggcggtcag
    13441 cagtgcagct ttctggttac ataaatatct gaacatcgtg gtggtgaaag ttatgttttc
    13501 tgttacaggg gagaccggac ttcacatcat gccccacggc agataagcca gagcatggcc
    13561 aagacgccgg tcagaaagcc ggagataaag acgctggtca gcagcaggag aatcagcgcg
    13621 cggagcgggg ggatatctcc ggcctgtatg gtgcctttat catcagtcgg catcagggtt
    13681 accggccagc agtttccgga ccaccgcggc ataacggctc ctgaaatctt cgacggagaa
    13741 tgcaccgaag gcggcattgt tgatatggta acggccacgg acatacacgg aaggcgtccc
    13801 cctcacgcca tattccttaa acaaccgttc ctgtaatgcc accatgtcat tcacggcggg
    13861 actttttata cttctgtcat actccccgcg actgataccg gtagcagaca taaacacccg
    13921 acggacatcg tccggggaat gcaggcgttt ctccaccatg tcggccgtga agaaggcctt
    13981 ctcgaccacg tcagtttcct tcatcatcat ggccagcgcc caggcctgtg tcagctcatg
    14041 gccgaggggg cccagcaggc tgacatggta cttgatcatc cggtcaccgt gcggcagtac
    14101 gtgccggatg gcccgggcca cgcccatcgt ctgtgagaac gcatagcagg gcggacagta
    14161 aaagaaaaat agttccacct cggcgggggc atcagccacc aagggagtta tgaactccca
    14221 ctcctgcgca atcacaggac gggcgcggcc aggtaaaaaa aaaagaaaat aatattcccc
    14281 tcaggaaaaa cagctcccgg gcataattca tcgtcacgga aacactccat ggataacaga
    14341 tatacagaat gaaaggccgc ttaacggtac cgcctgacag cagcagtaaa tcttaattca
    14401 tccggcacgg tcattaagcc ggcagccgga atattccggt catgagtttt ccagaataaa
    14461 aagcactgac acacaaaaga ccattgccat taatatgacg acggccagac aggcgtaata
    14521 aacgaatttc atgaacatga taaaataact ttcagtgata cttatccagc ttccgaccca
    14581 cattccgggc cgctctcctc cagtgaatga caccggttca ggtctgtata cagtgtcacc
    14641 atccccagaa gcatcagggt tggcaacagg gtggcatcat tcctgacgcc gaggcgcctg
    14701 aaagccaggc ctttctgggc tgaaatggtt ttgacgctgc gaaaacagag ggcagcaatc
    14761 tgcccgcagt tatagccctg cagcagcagt cggataaccc gcagttcagc cggactcagt
    14821 ccgccgtcgc tgttaaattc gatacaaagc cgatcgtacc atatccggct gatgtccccg
    14881 tcttccggga aagcggtcaa agcagacgcc ataatccggg cgctcccttt ccggcattta
    14941 ctttctcaag caccccgaca gcacggagtt gctcaagata tgagcggacc tggtagatac
    15001 tgagtccggc agcatcagca atatcgcgga ttttaacagg cgcgttgtcc gtactctgac
    15061 gctcccggat gatggagatg atgtttgtaa tgatggattc acccataaac ggccccactc
    15121 ttcaaggtta aaataaatgt atttaccact accacaaaat aatactaatc cattctatag
    15181 caacctcatt acgatatggt caaaccaaga cgaaaa
//
LOCUS       DAJVBX010000106        15136 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.106, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000106 DAJVBX010000000
VERSION     DAJVBX010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 15136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15136
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.106"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..417
                     /locus_tag="OPV72_002747"
     CDS             <1..417
                     /locus_tag="OPV72_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HCR9914998.1"
                     /translation="IGYKKTDNGIIPVREDSSGSEIEYLKKAARLQSGIISFFEYVKP
                     LIQKGNYAALSSVVLSEPFFELIARPSSAQLDALSSLTHSESAGSNAERIVLAKKLPL
                     KDKLFPGENYIKELNASYWKEGFKRLNRKKFWAKYN"
     gene            485..637
                     /locus_tag="OPV72_002748"
     CDS             485..637
                     /locus_tag="OPV72_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001528779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9914999.1"
                     /translation="MPWRDHVNPDGEVVSCCDNVIITGYHRLFVHPLWIFIMAFDVHS
                     RQSEAG"
     gene            671..1462
                     /gene="nei"
                     /locus_tag="OPV72_002749"
     CDS             671..1462
                     /gene="nei"
                     /locus_tag="OPV72_002749"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease VIII"
                     /protein_id="HCR9915000.1"
                     /translation="MPEGPEIRRAADNLEAAIKGKPLTDVWFAFAQLKPYESQLTGQL
                     VTRIETRGKALLTHFSNGLTLYSHNQLYGVWRVIDTGEIPQTTRILRVRLQTADKIIL
                     LYSASDIEMLTAEQLMTHPFLQRVGPDVLDARLTPEEVKARLLSPRFRNRQFSGLLLD
                     QSFLAGLGNYLRVEILWQVGLTGQHKAKDLNEAQLNALSHALLDIPRLSYTTRGQADE
                     NKHHGALFRFKVFHRDGEACERCGGIIEKTTLSSRPFYWCAHCQK"
     gene            complement(1517..2563)
                     /locus_tag="OPV72_002750"
     CDS             complement(1517..2563)
                     /locus_tag="OPV72_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HCR9915001.1"
                     /translation="MPILQWFLLFLLSLLISLIFLYLHLPAAMLLGPMIAGIVLSLRG
                     STLQLPRGIFLAAQAILGCMIAQNLTGSILTTLALYWPVVLFVLLVTLLSSAVVGWLL
                     VRYSSLPGNTGAWGSSPGGAAAMVAMAQDYGADIRLVAFMQYLRVLFVAGAAVLVTRL
                     ILGDSAATVSQQVVWFPPLSGNLLTTLLLAIVAGIAGRLMRIPSGTMLLPMLAGALLH
                     SQGIIEIELPEWLLAVAYMAIGWRIGLGFDRQVFFMALRPLPQILLSIFALMAICAAM
                     AWGMAYYMQIDFMTAYLATSPGGLDTVAAIAAGSSADMALIMAMQTLRLFSILLTGPA
                     VARFISTYAPKQPL"
     gene            complement(2700..3983)
                     /locus_tag="OPV72_002751"
     CDS             complement(2700..3983)
                     /locus_tag="OPV72_002751"
                     /EC_number="2.3.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate synthase"
                     /protein_id="HCR9915002.1"
                     /translation="MADTKAKITLTGDTAIELDVLKGTLGQDVIDIRSLGSKGVFTFD
                     PGFTSTASCESKITFIDGDEGILLHRGFPIDQLATDSNYLEVCYILLYGEKPTQEEYD
                     EFRTTVTRHTMIHEQITRLFHAFRRDSHPMAVMCGITGALAAFYHDSLDVNNPRHREI
                     AAFRLLSKMPTMAAMCYKYSIGQPFVYPRNDLSYAGNFLNMMFSTPCETYEVNPVLER
                     AMDRILILHADHEQNASTSTVRTAGSSGANPFACIAAGIASLWGPAHGGANEAALKML
                     EEISSVKHIPEFVRRAKDKNDSFRLMGFGHRVYKNYDPRATVMRETCHEVLKELGTKD
                     DLLEVAMGLEHIALNDPYFIEKKLYPNVDFYSGIILKAMGIPSSMFTVIFAMARTVGW
                     IAHWNEMHTDGMKIARPRQLYTGYDKRDFKSALKR"
     gene            4084..4329
                     /locus_tag="OPV72_002752"
     CDS             4084..4329
                     /locus_tag="OPV72_002752"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915003.1"
                     /translation="MHQSTVTSLLFGSPLCERGDDLGTEQWAFAGNGLINFELAANQE
                     RSNPSNVTCLSLITVLKEWVNIIVLLHNLLTGERVTP"
     gene            4723..5127
                     /gene="sdhC"
                     /locus_tag="OPV72_002753"
                     /gene_synonym="cybA"
                     /gene_synonym="dhsC"
     CDS             4723..5127
                     /gene="sdhC"
                     /locus_tag="OPV72_002753"
                     /gene_synonym="cybA"
                     /gene_synonym="dhsC"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase cytochrome b556 subunit"
                     /protein_id="HCR9915004.1"
                     /translation="MWALFMIRNVKKQRPVNLDLQTIRFPITAIASILHRVSGVITFI
                     AVGILLWLLGTSLSSPEGFQQAADIMDGFIVKFIMWGILTALAYHVIVGIRHMLMDFG
                     YLEETFEAGQRSAKISFVITVVLSLLAGVLVW"
     gene            5121..5468
                     /gene="sdhD"
                     /locus_tag="OPV72_002754"
                     /gene_synonym="cybS"
                     /gene_synonym="dhsD"
     CDS             5121..5468
                     /gene="sdhD"
                     /locus_tag="OPV72_002754"
                     /gene_synonym="cybS"
                     /gene_synonym="dhsD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017455938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase membrane anchor subunit"
                     /protein_id="HCR9915005.1"
                     /translation="MVSNASALGRNGVHDFILVRATAIVLTLYIIYMVGFFATSGELT
                     FEAWTGFFSSAFTKVFTLLALFSILIHAWIGMWQVLTDYVKPLAVRLILQLVIVVALV
                     VYVIYGFVVVWGV"
     gene            5468..7234
                     /gene="sdhA"
                     /locus_tag="OPV72_002755"
     CDS             5468..7234
                     /gene="sdhA"
                     /locus_tag="OPV72_002755"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase flavoprotein subunit"
                     /protein_id="HCR9915006.1"
                     /translation="MKLPVREFDAVVIGAGGAGMRAALQISQSGQTCALLSKVFPTRS
                     HTVSAQGGITVALGNTHEDNWEWHMYDTVKGSDYIGDQDAIEYMCKTGPEAILELEHM
                     GLPFSRLDDGRIYQRPFGGQSKNFGGEQAARTAAAADRTGHALLHTLYQQNLKNHTTI
                     FSEWYALDLVKNQDGAVVGCTALCIETCEVVYFKARATVLATGGAGRIYQSTTNAHIN
                     TGDGVGMALRAGVPVQDMEMWQFHPTGIAGAGVLVTEGCRGEGGYLLNKHGERFMECY
                     APNAKDLAGRDVVARSIMIEIREGRGCDGPWGPHAKLKLDHLGKEVLESRLPGILELS
                     RTFAHVDPVKEPIPVIPTCHYMMGGIPTKVTGQALTVNEQGEDVVIPGLFAVGEIACV
                     SVHGANRLGGNSLLDLVVFGRAAGLHLQESIAEQGVLRDASESDVEGSLDRLNRWNNN
                     RNGEDPVAIRKALQECMQHNFSVFREGDAMAKGLEQLKVIRERLKNARLDDTSSEFNT
                     QRVECLELDNLMETAYATAVSANFRTESRGAHSRFDFPERDDANWLCHTLYQPQTESM
                     TRRSVNMEPKLRPAFPPKIRTY"
     gene            7251..7967
                     /gene="sdhB"
                     /locus_tag="OPV72_002756"
     CDS             7251..7967
                     /gene="sdhB"
                     /locus_tag="OPV72_002756"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase iron-sulfur subunit
                     SdhB"
                     /protein_id="HCR9915007.1"
                     /translation="MKLEFSIYRYNPDVDNAPRMQDYTLEGEEGRDMMLLDALIQLKE
                     KDPSLSFRRSCREGVCGSDGLNMNGKNGLACITPISALTQSGKKIVIRPLPGLPVIRD
                     LVVDMGQFYAQYEKIKPYLLNNGQNPPAREHLQMPEQREKLDGLYECILCACCSTSCP
                     SFWWNPDKFIGPAGLLAAYRFLIDSRDTETDSRLEGMSDAFSVFRCHSIMNCVSVCPK
                     GLNPTRAIGHIKSMLLQRSA"
     gene            8493..11294
                     /gene="sucA"
                     /locus_tag="OPV72_002757"
     CDS             8493..11294
                     /gene="sucA"
                     /locus_tag="OPV72_002757"
                     /EC_number="1.2.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate dehydrogenase E1 component"
                     /protein_id="HCR9915008.1"
                     /translation="MQNSALKAWLDSSYLSGSNQSWIEQLYEDFLTDPDSVDANWRLT
                     FQQLPGTGVKPDQLHSKTREYFRRQALAGSRHSSTISDPDTNVKQVKVLQLINAYRFR
                     GHQHANLDPLGLWKQERVADLDPSFHDLTEADFQETFNVGSFASGKETMKLGELLDAL
                     KQTYCGPIGAEYMHITSTEEKRWIQQRIESGRAAFSADEKKRFLNELTAAEGLERYLG
                     AKFPGAKRFSLEGGDALIPMLKEMVRHAGNSGTREVVLGMAHRGRLNVLINVLGKKPQ
                     DLFDEFAGKHKEHLGTGDVKYHMGFSSDIETEGGLVHLALAFNPSHLEIVSPVVMGSV
                     RARLDRLDEPSSNKVLPITIHGDAAVTGQGVVQETLNMSKARGYEVGGTVRIVINNQV
                     GFTTSNPLDARSTPYCTDIGKMVQAPIFHVNADDPEAVAFVTRLALDFRNTFKRDVFI
                     DLVCYRRHGHNEADEPSATQPLMYQKIKKHPTPRKIYADKLEADKVATLEDATEMVNL
                     YRDALDAGECVVKEWRPMNMHSFTWSPYLNHEWDEAYPNKVEMKRLQELAKRISTVPE
                     AIEMQSRVAKIYGDRQAMAAGEKLFDWGGAENLAYATLVDEGIPVRLSGEDSGRGTFF
                     HRHAVIHNQTNGSTYTPLQHIHSGQGQFKVWDSVLSEEAVLAFEYGYATAEPRTLTIW
                     EAQFGDFANGAQVVIDQFISSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQL
                     CAEQNMQVCVPSTPAQVYHMLRRQALRGMRRPLVVMSPKSLLRHPLAVSTLDELANGS
                     FQPAIGEIDELDPKAVKRVVMCSGKVYYDLLEQRRKNDQKDVAIVRIEQLYPFPHKAV
                     QEALQPYAHVHDFVWCQEEPLNQGAWYCSQHHFREVIPFGAALRYAGRPASASPAVGY
                     MSVHQKQQQDLVNDALNVD"
     gene            11309..12517
                     /gene="odhB"
                     /locus_tag="OPV72_002758"
     CDS             11309..12517
                     /gene="odhB"
                     /locus_tag="OPV72_002758"
                     /EC_number="2.3.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate dehydrogenase complex
                     dihydrolipoyllysine-residue succinyltransferase"
                     /protein_id="HCR9915009.1"
                     /translation="MSSVDILVPDLPESVADATVATWHKKPGDAVVRDEVLVEIETDK
                     VVLEVPASADGILDAVLEEEGTTVTSRQILGRLREGNSAGKETSAKSEEKASTPAQRQ
                     QASLEEQNNDALSPAIRRLLAEHNLEASAIKGTGVGGRLTREDVEKHLAKGESKAPAV
                     EPAAQPALGARGEKRVPMTRLRKRVAERLLEAKNSTAMLTTFNEVNMKPIMDLRKQYG
                     EVFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTPRGL
                     VTPVLRDVDTLGMADIEKKIKELAVKGRDGKLTVEDLTGGNFTITNGGVFGSLMSTPI
                     INPPQSAILGMHAIKDRPMAVDGKVEILPMMYLALSYDHRLIDGRESVGFLVTIKELL
                     EDPTRLLLDV"
     gene            12659..13825
                     /gene="sucC"
                     /locus_tag="OPV72_002759"
     CDS             12659..13825
                     /gene="sucC"
                     /locus_tag="OPV72_002759"
                     /EC_number="6.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-forming succinate--CoA ligase subunit beta"
                     /protein_id="HCR9915010.1"
                     /translation="MNLHEYQAKQLFARYGLPAPVGYACTTPREAEEAASKIGAGPWV
                     VKCQVHAGGRGKAGGVKVVKSKEEIRAFAENWLGKRLVTYQTDANGQPVNQILVEAAT
                     DIGKELYLGAVVDRSSRRVVFMASTEGGVEIEKVAEETPHLIHKVALDPLTGPMPYQG
                     RELAFKLGLEGKLVQQFTKIFMGLATIFLERDLALIEINPLVITKQGDLICLDGKLGA
                     DGNALFRQPDLREMRDQSQEDPREAQAAQWELNYVALDGNIGCMVNGAGLAMGTMDIV
                     KLHGGEPANFLDVGGGATKERVTEAFKIILSDDNVKAVLVNIFGGIVRCDLIADGIIG
                     AVEEVGVNVPVVVRLEGNNAELGAKKLADSGLNIIAAKSLTDAAQQVVAAVEGK"
     gene            13825..14694
                     /gene="sucD"
                     /locus_tag="OPV72_002760"
     CDS             13825..14694
                     /gene="sucD"
                     /locus_tag="OPV72_002760"
                     /EC_number="6.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate--CoA ligase subunit alpha"
                     /protein_id="HCR9915011.1"
                     /translation="MSVLINKDTNVICQGFTGSQGTFHSEQAIAYGTQMVGGVTPGKG
                     GTTHLGLPVFNTVREAVEATGATASVIYVPAPFCKDSILEAIDAGIKLIITITEGIPT
                     LDMLTVKVKLDEAGVRMIGPNCPGVITPGECKIGIMPGHIHKPGKVGIVSRSGTLTYE
                     AVKQTTDYGFGQSTCVGIGGDPIPGSNFIDILKLFQEDPQTEAIVMIGEIGGSAEEEA
                     AAYIKDHVTKPVVGYIAGVTAPKGKRMGHAGAIIAGGKGTADEKFAALEAAGVKTVRS
                     LADIGEALKAIIK"
BASE COUNT         3665 a         3833 c         4233 g         3405 t
ORIGIN      
        1 attggctata aaaaaacgga taatggaata attcctgtac gtgaagatag cagtggttct
       61 gaaattgagt atttaaaaaa agcggcaaga ttgcaatcag ggattatttc tttttttgag
      121 tacgtcaaac cgctcataca aaaaggaaat tatgcagcac ttagtagtgt tgtattgtca
      181 gaaccttttt ttgaattgat agccagaccc tcaagcgctc aactggacgc cttatcttcc
      241 ctcacacatt cagagtccgc gggatctaac gcagaaagaa tcgtgctagc caaaaaactg
      301 cctttaaagg ataaactttt tcccggagaa aattatatca aagagttgaa tgccagttat
      361 tggaaagaag gctttaaaag gctcaacaga aaaaaatttt gggcaaaata taactaagcg
      421 tcatttaatt tcggtaggca gacaatcatt attaggcgct cgcccgacaa gggctgagtc
      481 gattatgccc tggcgcgatc acgttaaccc tgacggggaa gtggtctcgt gctgcgataa
      541 tgttattatc actggatacc accgcctgtt tgtccatccg ctgtggatat tcattatggc
      601 gttcgatgtg cattccagac agtcagaggc ggggtagtcc attaatcaac tgttaacaaa
      661 ggatattatc atgcctgaag gcccggaaat tcgtcgtgcg gcggataatc tggaggcggc
      721 aatcaaaggc aaacccttaa ccgatgtctg gtttgccttt gcacagttaa aaccgtatga
      781 atcgcagctt accggtcaac ttgttacccg gatagagacg cggggaaaag cgttattgac
      841 ccacttttca aatggcctga cgctctacag ccacaaccaa ctctatggcg tatggcgggt
      901 gatcgacacc ggtgaaatac cgcagaccac gcgtatatta cgcgtcaggc tacaaacggc
      961 ggataaaatt attctgcttt atagcgcgtc tgatatcgaa atgctgacag cagagcagct
     1021 catgacgcac ccttttttac agcgagtcgg tccggatgtg ttggacgcgc gtcttactcc
     1081 ggaagaggtt aaagctcgat tgctgtcgcc gcgttttcgc aaccgacaat tttccgggct
     1141 gttgctggat cagtcctttc tggcgggact ggggaattat ctgcgcgttg aaatcctctg
     1201 gcaggtagga ttaaccggac agcataaagc gaaagatctc aacgaggcgc aactgaatgc
     1261 gctttctcac gcgctgttgg atattccgcg cctttcctac acgactcgcg gtcaggcgga
     1321 tgagaacaag catcatggcg cactgtttcg ctttaaggtt ttccaccgtg acggtgaagc
     1381 gtgcgagcgg tgcggcggca ttattgaaaa gacaacactt tcctcacgcc cgttttactg
     1441 gtgcgcgcat tgccagaaat agccggaacc gccatcggcg agcggctatt gtctgatggc
     1501 gcgacgctta tcagccctac aaaggttgtt tgggcgcata ggttgatata aaacgggcca
     1561 ctgctggccc agttaacaga atgctgaaca gccgtagggt ttgcattgcc atgatgagcg
     1621 ccatatcggc actgcttcct gccgcgatcg cggcaaccgt atccagaccc ccgggactgg
     1681 tggcgagata agccgtcata aaatcaatct gcatgtagta agccattccc cacgccatcg
     1741 cggcgcaaat cgccatcagc gcgaaaattg acaataagat ttgcggcaat ggccgcagcg
     1801 ccataaaaaa cacctgtctg tcaaaaccca gcccaatacg ccagcctatc gccatatacg
     1861 ccacggccag cagccattcg ggtaattcaa tttcaatgat gccttgcgaa tggagaagcg
     1921 cgcctgccaa catggggagc agcatcgtgc cggaagggat acgcatcagg cgaccggcaa
     1981 tgcccgccac gatcgctaat agcagcgtcg tcaataaatt accgctaagc ggcggaaacc
     2041 agaccacctg ttggctgacc gttgccgcgc tgtcgccgag tatcaggcgt gtcaccagca
     2101 ccgccgcgcc agccacaaac agtacccgta gatactgcat aaacgccacc aggcggatat
     2161 ccgccccgta atcttgcgcc atcgctacca ttgccgccgc gccgcccggc gaagaccccc
     2221 atgcgccggt gttgccgggc agcgagctgt aacgtaccag cagccagccg actaccgcgc
     2281 tggaaagcag cgtcaccagc aacacaaaaa gcacgaccgg ccagtagagg gcgagggtgg
     2341 tcaatatcga accggttaga ttttgggcga tcatacagcc gagaatcgcc tgcgcggcga
     2401 gaaaaatacc gcgaggaagt tgtagcgtgc tacctcgcaa actcaacacg atacccgcaa
     2461 tcattggacc aagcagcatc gccgccggaa ggtgcagata gagaaaaata agggaaatga
     2521 gcagcgataa caggaacaac aaaaaccact gcaaaatcgg cattccatgc tccctgaatg
     2581 atatttagcg aaaccttaat taatcataga gagtaacggg gtaagaataa aataatgagg
     2641 ataagaaaaa agggaaaatg taccggatgg cgagggttgc gtcgccatcc ggttgtcaat
     2701 taacgcttca gcgccgattt aaaatcgcgt ttatcgtagc cggtatacag ctgacgagga
     2761 cgggcgattt tcatgccgtc agtgtgcatt tcattccagt gtgcaatcca gccaacggta
     2821 cgcgccatgg cgaagatcac ggtgaacata gaggacggaa tgcccatcgc tttcagaatg
     2881 atgccggagt agaagtctac gttcgggtac agtttcttct cgatgaagta cgggtcgttg
     2941 agcgcaatgt gctcaagccc catcgccact tccagcagat cgtctttggt gcccagctct
     3001 ttcagcactt cgtggcaggt ttcacgcatc acggtggcgc gcggatcgta gtttttgtaa
     3061 acacggtgac cgaagcccat caggcggaaa gaatcattct tgtctttcgc acggcgaaca
     3121 aattccggaa tgtgtttaac agagctgatt tcttccagca ttttcagcgc ggcttcgttg
     3181 gcgccgccgt gcgcgggtcc ccacagggag gcgatcccgg cggcaatgca ggcgaacggg
     3241 ttggcgccgc ttgaacctgc ggtacgtacc gttgacgtag aggcgttctg ctcatggtca
     3301 gcgtgcagga tcagaatacg gtccatcgcg cgctccagta ccggattcac ttcataggtt
     3361 tcacacggcg tggagaacat catgttcagg aagttaccgg cgtaggaaag gtcgttgcgc
     3421 ggataaacaa acggctgacc gattgaatat ttgtaacaca tcgccgccat ggtcggcatt
     3481 ttggacagca ggcggaacgc cgcgatttca cggtggcgcg gattgttcac atccagcgag
     3541 tcgtggtaga acgccgccag cgcgccagtg atcccgcaca ttaccgccat cggatgtgag
     3601 tcgcgacgga aagcatggaa caggcgagtg atttgctcat ggatcatcgt atggcgggtg
     3661 actgtcgttc tgaactcgtc atactcttcc tgcgtcggtt tttcgccgta cagcaggatg
     3721 taacagactt ccagatagtt ggaatcggta gcaagctggt caatcgggaa accgcgatgc
     3781 aacaaaatgc cttcgtcgcc gtcgatgaag gtgattttag attcgcagga tgcggtagag
     3841 gtgaaaccag ggtcaaaagt aaaaactcct tttgaaccga gactacgaat atcaataaca
     3901 tcttgaccga gtgtgccttt tagcacatcc agttcaatag cagtgtcacc agtaagggtg
     3961 atttttgcct ttgtatcagc catttacggt ctccttagcg ccttattgct taagactgcc
     4021 ggaactcaga cttgccttct ccacgtcatc ttcctcgtcg ttagtgcagg gaaaattctg
     4081 tgtatgcatc aatcaaccgt taccagtttg ttatttggct cgccgctctg tgaaagaggg
     4141 gatgacctgg gtacagagca atgggcgttt gcaggtaacg gcttgattaa tttcgaatta
     4201 gcagcaaatc aggaacgtag caatccgagt aatgtaacct gtctatcact aataactgtc
     4261 ctgaaagaat gggtcaatat cattgtactg ttacataact tattaacagg tgaaagagtg
     4321 accccataac ttttacgcat tatatgcttt ttctggtgtt gtttgtaaca attttgttta
     4381 atgtttgtca aatcagatga ttgaaaatta aaaaaatgtt gttatcgtga cctgtgtcac
     4441 tgttcaggat aaaacccgac aaactatatg taggttaatt gtaatgattt tgtgaacgtc
     4501 ctatactgcc gccaggtctc cggaataccc tgcaatcccg agccacccag cgttgtaacg
     4561 tgtcgtttta gctactggaa gcagtgtttt acatgacgcg cagttataga aaggacgctg
     4621 tctgacccgc acgcagaccg gaggaaggaa atcccgtcgt ctttctggct acaggtagat
     4681 tcacctctgt aaccgaagtc ttaagggaat aataagaaca gcatgtgggc gttattcatg
     4741 ataagaaatg tgaaaaaaca aagacctgtc aatctggatc tacaaacgat tcggttcccc
     4801 atcacagcga tagcgtccat tctccatcgc gtatccggtg tgattacttt catcgccgtc
     4861 ggcatactac tgtggctact gggcaccagc ctctcttctc cggaaggatt ccagcaggcc
     4921 gccgacatca tggacggctt catcgttaaa tttatcatgt ggggcatcct taccgcgctg
     4981 gcgtatcacg tcatcgtggg aattcgtcac atgttaatgg attttggcta tctggaagaa
     5041 acattcgaag cgggtcaacg ctctgccaaa atctcttttg ttatcactgt cgtgctttca
     5101 cttctcgcag gagtcctcgt atggtaagca acgcctccgc attaggacgc aatggcgtac
     5161 atgacttcat cctggtccgt gctaccgcta tcgttctgac gttatacatc atctacatgg
     5221 tgggtttttt cgccacgagc ggcgaactga cctttgaagc ctggaccggt ttcttctcat
     5281 cggccttcac caaagtcttc actctgctgg cgcttttttc catcttaatt catgcctgga
     5341 tcggcatgtg gcaggtgtta accgactacg ttaaaccact ggcagtgcgt ctgatactgc
     5401 aactcgttat tgttgttgcg ctggtggttt acgtcatcta tggatttgtt gtggtgtggg
     5461 gtgtgtaatg aaactgccag tcagagaatt tgatgctgtt gtgattggtg ccggtggcgc
     5521 aggtatgcgc gcggcgctgc aaatttccca gagcggccaa acctgtgcgc tgctctcgaa
     5581 agtcttcccg acccgttccc ataccgtttc cgcgcagggc ggtatcaccg tggcgctcgg
     5641 caatacccat gaagataact gggaatggca catgtacgac accgtaaaag ggtcggacta
     5701 cattggtgac caggatgcca tcgaatatat gtgtaagacc ggaccggaag cgattctgga
     5761 actggagcac atggggctac cgttctcccg tcttgatgat ggacgtatct atcagcgccc
     5821 gttcggcggc cagtcgaaaa actttggcgg cgagcaggcg gcacgtaccg cggcggcggc
     5881 tgaccgtacc ggtcacgcct tgctacatac gctgtatcaa cagaatttga aaaaccacac
     5941 cacgattttc tccgaatggt atgcgctgga tctggtgaaa aaccaggatg gcgcggtggt
     6001 ggggtgtacc gcactgtgca tcgaaacctg tgaagtggtg tacttcaaag ctcgcgcgac
     6061 ggtgctggcg accggcggcg caggccgtat ctaccagtcc accaccaacg ctcatatcaa
     6121 taccggtgac ggtgtcggta tggcgctgcg tgccggtgtc ccggtgcagg atatggaaat
     6181 gtggcagttc cacccgaccg gcatcgccgg ggcgggcgtg ctggtgacag aaggctgccg
     6241 cggcgaaggc ggttacctgc tgaacaaaca cggcgagcgc tttatggagt gttatgcgcc
     6301 gaacgccaaa gaccttgcgg gtcgtgacgt ggtggcgcgt tccatcatga tcgaaatccg
     6361 tgaaggtcgc ggctgtgatg gtccgtgggg gccgcacgct aaactgaaac tggatcatct
     6421 gggtaaagag gtgctggaat ctcgcctgcc gggtatcctg gagctgtccc gcactttcgc
     6481 tcacgtcgat ccggtgaaag agccgattcc ggttatcccg acctgccact acatgatggg
     6541 cggtattccg actaaagtga ccggtcaggc gctgaccgtg aacgagcagg gcgaagacgt
     6601 ggtgattccg gggctgtttg cggtaggcga aatcgcctgt gtatcggttc acggcgccaa
     6661 ccgtctgggc ggtaactcac tgctggatct ggtggtcttt ggccgcgcgg cggggctgca
     6721 tttacaggaa tccatcgccg agcagggcgt gctgcgcgac gccagcgagt ctgacgttga
     6781 aggttctctg gatcgcctga atcgctggaa caataaccgc aatggcgaag atccggtggc
     6841 tatccgcaaa gcattgcagg agtgtatgca gcataacttc tccgtattcc gtgaaggcga
     6901 cgcgatggcg aaagggcttg agcagttgaa agtgatccgc gagcgtctga aaaacgcccg
     6961 tctggatgac acgtccagcg agtttaatac ccagcgtgtt gagtgtctgg agctggataa
     7021 cctgatggaa accgcctacg ccactgccgt atcagccaac ttccggacgg aaagccgcgg
     7081 cgcgcatagc cgcttcgatt tcccggagcg tgatgatgcc aactggttgt gtcataccct
     7141 gtatcagccg caaacggaat ccatgacgcg ccgaagcgtc aatatggaac cgaaactgcg
     7201 tccggcgttc ccgccgaaga ttcgtactta ttaattgcgg agacaggatg atgaaactcg
     7261 aattttcgat ttatcgttat aacccggatg tcgataacgc tccgcgtatg caggattaca
     7321 ccctggaagg cgaagaaggg cgcgacatga tgctgctgga tgcgttaatc cagcttaaag
     7381 aaaaagatcc cagcctttct ttccgccgtt cctgccgcga aggtgtgtgt ggttctgatg
     7441 gtttgaatat gaacggtaag aatggtctgg cctgtattac tcctatttcg gcgctgactc
     7501 agtcgggtaa gaagattgtg attcgcccgc tgcccggttt gccggtgatc cgcgatttgg
     7561 tggtagacat ggggcaattc tacgcacaat atgagaagat taagccttac ttattgaata
     7621 atgggcaaaa tccaccggca cgtgagcatt tacagatgcc ggagcagcgt gaaaaactcg
     7681 atgggctgta tgaatgtatt ctttgcgcct gttgctcaac atcctgcccg tcattctggt
     7741 ggaacccgga taagtttatc ggtccggcgg ggctgctcgc ggcgtatcga ttcctgatcg
     7801 atagtcgtga taccgagact gacagtcgtc tggaagggat gagcgatgca ttcagcgtat
     7861 tccgctgtca cagcattatg aactgcgtca gtgtatgtcc taagggactg aacccgacgc
     7921 gcgctatcgg ccatattaag tcgatgctgt tgcagcgtag cgcgtaagta gttgtagtgg
     7981 ttgccggatg gcgacgtacc gtcttatccg gcctacgggt tacgtattct gtaggcctga
     8041 taagccaggt gccatcgggc aatagaagtg caggaaacct ctaaaaactg ccatatgatt
     8101 agtaataatc gagatgttca gagcgagaca aggcgcggtc tgaacgaatc ttcgggagca
     8161 tagttaacta tgtgaccgga gtgagcgaag gccgcaacgc agtcgtagcc tgaacagcga
     8221 agattattag acagttttta aaggttcctt agcggacgca gatgacacga cagtccgcaa
     8281 caagtgaacc ccggcacgca tacagcgtat gcgtggttag tatccacggc gaaatactcg
     8341 tcatagttca cgttgcatgt gcgttggctg cacttgctca ccccagtcac ttactggatg
     8401 taagctccca gggattcgca agcttgccgc cttcctgaaa cgtgacctat ttagagtatt
     8461 aaataagcag aaaagatgct taagggatca cgatgcagaa cagcgctttg aaagcctggt
     8521 tggactcttc ttacctctct ggttcgaatc agagctggat agaacagctc tatgaagact
     8581 tcttaaccga tcctgactcg gtagacgcta actggcgttt gacgttccag cagttacctg
     8641 gtaccggagt caaaccggat caactccatt caaaaacacg tgaatatttc cggcggcagg
     8701 cgttggctgg ctcacgtcac tcttctacga tttccgaccc tgacaccaat gtgaagcagg
     8761 ttaaagtcct gcagcttatc aacgcttatc gtttccgtgg ccatcagcat gcaaacctcg
     8821 atccgctggg actgtggaaa caagaacgcg tggcggatct ggacccttct ttccatgatt
     8881 tgaccgaggc cgatttccag gaaaccttca atgtcggctc ctttgccagc ggcaaagaga
     8941 cgatgaagct gggggagctg ctcgacgcgc tcaaacagac ctactgcggc ccgattggcg
     9001 ctgagtatat gcacatcacc agcaccgaag agaaacgctg gatccaacag cgcatcgaat
     9061 ccggtcgtgc ggcctttagc gctgacgaga aaaaacgctt cctgaacgaa ctgaccgccg
     9121 ctgaagggct ggaacgttat ctgggcgcca aattcccggg tgcgaaacgt ttctcgctcg
     9181 aggggggaga tgcgctgata cctatgctga aagagatggt tcgccatgcg ggtaacagcg
     9241 gcactcgcga agtggtgctg gggatggcgc accgcggtcg tctgaacgtg ctgatcaacg
     9301 tactgggtaa aaaaccgcag gatctgttcg acgagtttgc cggtaaacat aaagaacatc
     9361 tgggtaccgg cgacgtgaag tatcacatgg gcttctcgtc agatatcgaa actgaaggcg
     9421 gtctggttca cctggcgctg gcgtttaacc catcgcatct ggaaattgtg agcccggtgg
     9481 tgatgggctc cgtgcgcgcc cgtctggacc gactggacga accgagcagt aataaagtgc
     9541 tgccgatcac tattcacggc gacgccgcgg tgaccggcca gggcgtggtt caggaaaccc
     9601 tgaacatgtc gaaagcgcgc ggttacgaag tgggcggtac ggtacgtatc gttatcaaca
     9661 accaggtggg cttcactacc tctaacccac tggatgcgcg ttcaacgcct tactgcaccg
     9721 atatcggtaa aatggtccag gcgccgattt tccacgtcaa tgcggacgat ccggaagccg
     9781 tcgcttttgt gacccgtctg gcgctggact tccgtaatac ctttaaacgc gatgtgttca
     9841 tcgatctggt gtgctaccgc cgtcacggcc acaacgaagc cgacgagcca agcgcaaccc
     9901 agccgctgat gtaccagaaa atcaaaaagc atccgacgcc gcgtaaaatc tacgccgaca
     9961 agctggaagc tgataaggtc gcaacgctgg aagatgccac cgaaatggtc aacctctatc
    10021 gcgatgcgct ggatgcaggc gaatgcgtgg tgaaagagtg gcgtccgatg aatatgcact
    10081 cgttcacctg gtcgccgtat ctaaaccacg aatgggatga agcatacccg aacaaggtag
    10141 aaatgaagcg tctgcaggag ctggcaaaac gtatcagcac cgtgccggaa gccattgaaa
    10201 tgcagtctcg cgtggcgaaa atttatggcg accgtcaggc aatggcggca ggcgagaaat
    10261 tgtttgactg gggcggcgcg gaaaatctgg cttacgccac gctggtcgat gaaggcattc
    10321 cggtgcgcct gtccggggaa gactccggtc gcggcacctt cttccatcgt catgcggtga
    10381 tccacaacca gacgaacggc tcaacgtata cgccgttgca gcatattcac agcggtcagg
    10441 gacagtttaa agtctgggac tccgtgctgt ctgaagaagc ggtactggct tttgaatacg
    10501 gttatgccac ggcggaacca cgtaccctga ctatctggga agcgcagttt ggcgattttg
    10561 ccaacggcgc gcaggtagtg attgaccagt tcatctcctc tggcgagcag aaatggggcc
    10621 ggatgtgcgg tctggtgatg ctgttgccgc acggctatga agggcagggg ccggagcact
    10681 cctccgcgcg tctggaacgt tatctgcaac tttgcgccga gcagaatatg caggtttgcg
    10741 taccgtccac tccggcgcag gtctaccata tgctgcgccg tcaggcgctg cgcgggatgc
    10801 gtcgtccgct ggtggtgatg tcgccgaaat cgctgctgcg tcacccgctg gcggtttcca
    10861 cgcttgatga actggcgaac ggttccttcc agccggccat tggcgaaatt gacgagctgg
    10921 accctaaagc cgtaaaacgc gtggtaatgt gttctggtaa ggtttattac gacctgctgg
    10981 aacaacgtcg caaaaacgac cagaaagatg tcgctatcgt gcgcatcgaa cagctctatc
    11041 cgttcccgca taaagcggtg caggaagcgc tgcaaccata cgctcacgtc catgattttg
    11101 tctggtgcca ggaagagccg ctcaaccagg gcgcatggta ctgcagtcag catcatttcc
    11161 gtgaagtgat tccgtttggg gccgctctgc gttatgcagg tcgcccggcc tccgcctctc
    11221 cggcggtagg gtatatgtcc gttcaccaga aacagcaaca agatctggtt aatgacgcgc
    11281 tgaacgtcga ttaaataaag gataaataat gagtagcgta gatattcttg ttcccgacct
    11341 gcctgagtcc gtagcggacg cgaccgtcgc cacctggcat aaaaaaccgg gcgatgcggt
    11401 tgttcgtgac gaagtgctgg tagaaatcga aactgacaaa gtggtactgg aagtaccggc
    11461 atcagcggac ggcattctgg atgcggttct ggaagaagag gggacgactg tcacctctcg
    11521 ccagatcctg ggtcgcctgc gtgaaggcaa cagcgcgggt aaagagacca gcgcgaaatc
    11581 tgaagagaaa gcgtctacgc cggcacagcg ccagcaggcg tcgctggaag aacaaaacaa
    11641 cgatgcgctc agcccggcga tccgtcgcct gctggctgaa cacaatctgg aagccagcgc
    11701 cattaaaggc actggtgtgg gtgggcgtct gacccgtgaa gatgtggaaa aacatctggc
    11761 gaaaggcgag tctaaagcac ccgctgttga acctgcagca caacccgctc tgggcgcgcg
    11821 cggcgaaaaa cgcgtgccaa tgacccgcct gcgtaagcgc gtggccgagc gtctgctgga
    11881 agcgaaaaat tccaccgcca tgctgacgac cttcaatgaa gtcaacatga agccgattat
    11941 ggatttgcgt aagcagtatg gcgaagtgtt tgaaaaacgt catggtatcc gcctgggctt
    12001 tatgtccttc tacgtgaaag cggtagtgga agcgctgaag cgttatccgg aagtgaacgc
    12061 ctctatcgac ggcgatgacg tggtgtatca caactacttt gatgtgagca tggcggtgtc
    12121 tacgccgcgc ggcctggtca cgccggtcct gcgtgacgtg gatacgctgg gcatggctga
    12181 catcgagaaa aaaattaaag aactggctgt caaaggccgc gacggcaagc tgaccgtaga
    12241 agacctgacc ggcggtaact ttaccattac caacggcggc gtattcggtt cgctgatgtc
    12301 taccccgatc atcaacccgc cgcagagcgc gattctggga atgcatgcta ttaaagacag
    12361 gccgatggcg gtggatggca aggtggaaat cctgccgatg atgtacctgg cgctctctta
    12421 cgatcatcgc ctgatcgatg gtcgcgaatc cgtgggcttc ctggtcacca tcaaagagtt
    12481 gctggaagat ccgacccgtc tgctgttgga cgtgtagtca gcaagagcat cacctgctac
    12541 ctgtaggccg gataaggcgt tcacgccgcc atccggcgat ggtgtaatgc ctgatggcgc
    12601 gcagctttca ggcctacagg tctaaagata acgattacct gaaggatgga cagaacacat
    12661 gaacttacat gaatatcagg caaaacaact ttttgcccgc tatggcttac cggcgccggt
    12721 gggttatgcc tgtactactc cgcgtgaagc cgaagaagcc gcgtctaaaa tcggtgccgg
    12781 cccgtgggta gtgaaatgtc aggttcacgc tggcggccgc ggcaaagcgg gcggtgtgaa
    12841 ggtagtaaaa agcaaagaag agattcgcgc ctttgcggaa aactggctgg gcaaacgtct
    12901 ggtgacctat caaacagacg ctaatggcca accggtaaac cagattctgg ttgaagcggc
    12961 gaccgacatc ggcaaagaac tgtacctcgg cgcggtggtt gaccgtagtt ctcgtcgcgt
    13021 ggtctttatg gcgtctaccg aaggtggcgt agagatcgaa aaagttgcgg aggaaacccc
    13081 gcatctgatc cataaagtcg cgctcgatcc gctgaccggc ccgatgccgt atcagggacg
    13141 ggaactggcg ttcaaattgg gtctggaagg taaactggtg cagcagttca ccaaaatctt
    13201 tatgggcctg gcaaccattt ttcttgagcg cgacctggcg ctaatcgaaa ttaatccgct
    13261 ggtgatcact aagcagggcg atctgatttg cctcgacggc aagctgggcg ctgacggcaa
    13321 cgcgctgttc cgccagccgg atctgcgcga aatgcgcgac cagtctcagg aagacccgcg
    13381 tgaagcgcag gcggcacagt gggaactgaa ctacgtcgcg ctggacggca acatcggttg
    13441 catggtgaac ggcgcgggcc tggcgatggg caccatggac atcgttaagc tgcatggcgg
    13501 cgaaccggct aacttccttg acgtaggcgg cggcgcaacc aaagagcgcg tcaccgaagc
    13561 gtttaaaatt atcctctcgg atgacaacgt gaaagcggtt ctggttaaca tcttcggcgg
    13621 tatcgtccgt tgtgacctga ttgccgacgg tatcatcggc gcggtggaag aagtgggcgt
    13681 gaacgttccg gtggtggtgc gtctggaagg caacaacgcc gaactcggcg cgaagaaact
    13741 ggctgacagt ggcctgaata ttattgcagc gaaaagtctg acggatgcag ctcagcaggt
    13801 tgttgccgca gtggagggga aataatgtcc gttttaatta ataaagatac caacgttatc
    13861 tgccagggct tcaccggtag ccaggggact ttccactccg aacaggcgat tgcttacggt
    13921 acgcaaatgg tcggcggcgt aacgccgggc aaaggcggca ccacgcatct gggtctgccg
    13981 gtgttcaaca ccgtgcgcga agcggtagaa gctaccggtg cgaccgcatc cgttatctac
    14041 gtcccggcgc cgttctgcaa agactccatt ctggaagcga tcgacgcagg catcaaactg
    14101 attatcacca tcaccgaagg tattccgacg ctggatatgc tgaccgtgaa agtgaagctg
    14161 gacgaagcgg gcgtacgcat gatcggcccg aactgcccag gtgtgatcac cccgggcgaa
    14221 tgcaaaatcg gcatcatgcc gggtcacatt cataagccgg gtaaagtggg tatcgtttcc
    14281 cgttccggca cgctgaccta tgaagcggtt aagcagacca ccgactacgg tttcggccag
    14341 tccacctgcg tgggtatcgg cggcgacccg attccgggct ctaacttcat cgacattctg
    14401 aaactgttcc aggaagatcc gcagactgaa gcgatcgtga tgatcggcga gatcggcggc
    14461 agcgcggaag aagaagcggc ggcttatatt aaagaccacg tgaccaagcc ggttgttggc
    14521 tatatcgcgg gcgttaccgc gccgaaaggc aaacgtatgg gccacgctgg cgccatcatt
    14581 gccggtggta aaggtaccgc tgatgagaaa ttcgctgctc tggaagcggc tggcgtgaag
    14641 acggttcgca gcctggccga tatcggcgaa gcgctgaaag caattataaa ataaaaactc
    14701 gctgttcctg cgggaacaga taaatgtccg ttttcgacat ggttggccac ctttacggtg
    14761 gcctttttta tggttttatt gtttgtggca aagtacgggt gaagcatccg ggatataaaa
    14821 ttattggctt tgtaaatatt gaggtatagg aaaatgatga ctcattaaaa aaacatggtg
    14881 gagtctgaaa ataattgata ataaccgtct ggcagcggca gtaaatttac tcagtttgcc
    14941 ggttaactct ttttcagcaa atacagatgc tgtcttagtg aaagacctgc cgacctcact
    15001 ggagacggat tatgcgcttt ccgccatgaa aaaaacgcat tgcagcatta cactatgttg
    15061 atgctaacct ctatagtaaa ttgacgcttg actctgtggc cgcgcatgtt tgcctgagcg
    15121 cgaactacac gtctcc
//
LOCUS       DAJVBX010000107        15126 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.107, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000107 DAJVBX010000000
VERSION     DAJVBX010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 15126)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15126
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.107"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(40..1335)
                     /gene="phoR"
                     /locus_tag="OPV72_002761"
     CDS             complement(40..1335)
                     /gene="phoR"
                     /locus_tag="OPV72_002761"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate regulon sensor histidine kinase PhoR"
                     /protein_id="HCR9915012.1"
                     /translation="MLERLSWKRLVLELVLCCIPALILSAFFGYLPWFLLAAVTGLLV
                     WHFWNLLRLSWWLWVDRSMTPPPGRGSWEPLLYGLHQMQLRNKKRRRELGNLIKRFRS
                     GAESLPDAVVLTTEEGGIFWCNGLAQQILGLRWPDDNGQNILNLLRYPEFTQYLKTRD
                     FTRPLHLVLNTGRHLEIRVMPYTDKQLLMVARDVTQMHQLEGARRNFFANVSHELRTP
                     LTVLQGYLEMMQEQALEGATREKALHTMREQTYRMEGLVKQLLTLSKIEVAPALLLNE
                     KVDVPMMLRVVEREAQTLSQQKHTFTFAVDDSLSVLGNEEQLRSAISNLVYNAVNHTP
                     AGTHITVSWRRAAHGAEFCIQDNGPGIAAEHIPRLTERFYRVDKARSRQTGGSGLGLA
                     IVKHALNHHESRLEIDSSPGKGTRFSFVLPERLIAKNSD"
     gene            complement(1405..2094)
                     /gene="phoB"
                     /locus_tag="OPV72_002762"
     CDS             complement(1405..2094)
                     /gene="phoB"
                     /locus_tag="OPV72_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000113934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate response regulator transcription
                     factor PhoB"
                     /protein_id="HCR9915013.1"
                     /translation="MARRILVVEDEAPIREMVCFVLEQNGFQPVEAEDYDSAVNKLNE
                     PWPDLILLDWMLPGGSGLQFIKHLKREAMTRDIPVVMLTARGEEEDRVRGLETGADDY
                     ITKPFSPKELVARIKAVMRRISPMAVEEVIEMQGLSLDPGSHRVMTGDSPLDMGPTEF
                     KLLHFFMTHPERVYSREQLLNHVWGTNVYVEDRTVDVHIRRLRKALEHSGHDRMVQTV
                     RGTGYRFSTRF"
     gene            2309..3511
                     /gene="sbcD"
                     /locus_tag="OPV72_002763"
     CDS             2309..3511
                     /gene="sbcD"
                     /locus_tag="OPV72_002763"
                     /EC_number="3.1.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease subunit SbcD"
                     /protein_id="HCR9915014.1"
                     /translation="MRILHTSDWHLGQNFYSKSRAAEHQAFLDWLLETAQAHQVDAII
                     VAGDIFDTDSPPSYARELYNRFVVNLQQTGCHLVVLAGNHDSVATLNESRDILAFLNT
                     TVIASAGYAPRLLHRRDGSPGAVLCPIPFLRPRDIITSQAGLSGSEKQQQLLHAIADY
                     YQQQYQEACLLRGERKLPVIATGHLTTVGASKSDAVRDIYIGTLDAFPAQHFPPADYI
                     ALGHIHRAQCVGGTEHIRYCGSPIALSFDECGKSKCVHLVTFDQGKWQSTESLAVPVT
                     QLLAVLKGDLASITEQLEQWRGVEQSPPVWLDIEITTDDYLHDIQRRIQALTESLPVE
                     VLLVRRSREQRERSLANERRETLSELSVEEVFARRLALEALDTPQRERLNQLFSSTLY
                     ALNEEHEA"
     gene            3508..6649
                     /gene="sbcC"
                     /locus_tag="OPV72_002764"
                     /pseudo
     CDS             3508..6649
                     /gene="sbcC"
                     /locus_tag="OPV72_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459390.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease subunit SbcC"
     gene            6822..7994
                     /gene="araJ"
                     /locus_tag="OPV72_002765"
                     /pseudo
     CDS             6822..7994
                     /gene="araJ"
                     /locus_tag="OPV72_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459389.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter AraJ"
     gene            complement(8014..8922)
                     /gene="mak"
                     /locus_tag="OPV72_002766"
     CDS             complement(8014..8922)
                     /gene="mak"
                     /locus_tag="OPV72_002766"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase"
                     /protein_id="HCR9915015.1"
                     /translation="MRIGIDLGGTKTEVIALDDAGEQRFRHRLPTPREDYQQTIETIA
                     TLVDMAEQATGQTGSVGIGIPGSLSPYTGVVKNANSTWLNGQPFDSDVSRRLKREVRL
                     ANDANCLAVSEAVDGAAAGAQTVFAVIIGTGCGAGVALNGRAHIGGNGTAGEWGHNPL
                     PWMDDDELRYREEIPCYCGKQGCIETFISGTGFATDYQRLSGKTLKGDEIIRLVDAQD
                     AVAELAISRYELRLAKALSHVVNILDPDVIVLGGGMSNVERLYKTVPSLMKSFVFGGE
                     CETPVRKARHGDSSGVRGAAWLWPLA"
     gene            9048..9959
                     /gene="rdgC"
                     /locus_tag="OPV72_002767"
     CDS             9048..9959
                     /gene="rdgC"
                     /locus_tag="OPV72_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination-associated protein RdgC"
                     /protein_id="HCR9915016.1"
                     /translation="MLWFKNLMVYRLSRDITLRAEEMEKQLASMTFTPCGSQDMAKMG
                     WVPPMGSHSDALTHTANGQIIICARKEEKILPSPVIKQALEAKIQKLEADQGRKLKKT
                     EKDSLKDEVLHSLLPRAFSRFSQTMMWIDTVNGLIMVDCASAKKAEDTLALLRKSLGS
                     LPVVPLALENPIELTLTEWVRSGTVAQGFQLLDEAELKAMLEDGGVIRAKKQDLVSDE
                     IAVHIEAGKVVTKLALDWQQRIQFVMCDDGSIKRLKFCDELRDQNEDIDREDFAQRFD
                     ADFILMTGELAALIQSLVEGLGGEAQR"
     gene            complement(9997..10281)
                     /gene="ppnP"
                     /locus_tag="OPV72_002768"
     CDS             complement(9997..10281)
                     /gene="ppnP"
                     /locus_tag="OPV72_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine/purine nucleoside phosphorylase"
                     /protein_id="HCR9915017.1"
                     /translation="MLQSNEYFSGKVKSIGFTSSSTGRASVGVMAEGEYTFGTAEPEE
                     MTVVSGALKVLLPGTVEWKVYTAGEVFNVPGHSEFHLQVAEPTSYLCRYL"
     gene            complement(10352..11029)
                     /locus_tag="OPV72_002769"
     CDS             complement(10352..11029)
                     /locus_tag="OPV72_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AroM family protein"
                     /protein_id="HCR9915018.1"
                     /translation="MSASLAILTIGVVPMSEVLPLLTEYIDEQHITHHSLLGKMSRED
                     VMADYAVEPGDDLLLTLLNDNQIAHVSRQKVERDLQSVVEVLDNQGYDVIILMSTAAI
                     KSTAARNSILLEPLRIIPPLVASIVDGHQVGAIVPVAELLAAQEKKWQVLQMPPVYSL
                     ANPVHGSEQQLIDAGQALLDQGADVIMLDCLGFHQRHRDILQQALDVPVLLSNVLIAR
                     LASELLV"
     gene            complement(11280..11471)
                     /gene="yaiA"
                     /locus_tag="OPV72_002770"
     CDS             complement(11280..11471)
                     /gene="yaiA"
                     /locus_tag="OPV72_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YaiA"
                     /protein_id="HCR9915019.1"
                     /translation="MPTRPPYPREAYIVTIEKGTPGQTVTWYQLRADHPKPDSLISEH
                     PTAEEAMDAKKRYEDPDKS"
     gene            complement(11498..12043)
                     /gene="aroL"
                     /locus_tag="OPV72_002771"
     CDS             complement(11498..12043)
                     /gene="aroL"
                     /locus_tag="OPV72_002771"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase AroL"
                     /protein_id="HCR9915020.1"
                     /translation="MMQPLYLVGPRGCGKTTIGMALAQATGFRFADTDRWLQSHVQMS
                     VADIVEKEGWGGFRARETAALEAVSAPSTVVATGGGIILTEYNRRYMHRVGVVIYLCA
                     PVSTLVNRLEAEPEADLRPTLTGKPLSEEVREVLEQRDALYRETAHYIIDATKAPAQV
                     VSEIIAALPPSTQRLQGDVYT"
     gene            complement(12228..12683)
                     /locus_tag="OPV72_002772"
     CDS             complement(12228..12683)
                     /locus_tag="OPV72_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HCR9915021.1"
                     /translation="MTIWVDADACPNVIKEILYRAAERMQLPLILVANQALRVPPSRF
                     IRTLRVAAGFDVADNEIVRQCEAGDLVITADIPLAAEVLEKGAAALNPRGERYSDATI
                     RERLTMRDFMDTLRASGVQTGGPNTLSPRDRQHFAAELDKWWLESQRKK"
     gene            12823..13632
                     /gene="proC"
                     /locus_tag="OPV72_002773"
     CDS             12823..13632
                     /gene="proC"
                     /locus_tag="OPV72_002773"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HCR9915022.1"
                     /translation="MEKKIGFIGCGNMGKAILGGLIASGQVLPGQIWVYTPSPDKVAA
                     LHDQYGINAAQSAQEVAQVADIVFGAVKPGIMVKVLSEISSSLNKDSLVVSIAAGVTL
                     DQLARALGHDRKIIRAMPNTPSLVNAGMTSVTPNALVTPEDTADVLNIFRCFGEAEVI
                     AEPMIHPVVGVSGSSPAYVFMFIEAMADAAVLGGMPRAQAYKFAAQAVMGSAKIVLET
                     GKHPGELKDMVCSPGGTTIEAVRVLEERGFRAAVIEAMTKCMEKSEALSKS"
     gene            complement(13647..14759)
                     /gene="adrA"
                     /locus_tag="OPV72_002774"
                     /gene_synonym="dgcC"
     CDS             complement(13647..14759)
                     /gene="adrA"
                     /locus_tag="OPV72_002774"
                     /gene_synonym="dgcC"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase AdrA"
                     /protein_id="HCR9915023.1"
                     /translation="MFPKIMNDENFYRKAVEQAVAPPDPSDDRQRSGLRFARRIRLPR
                     AVGLGGMLLPVAAVLVSQPVFGGWWLLLVGWSFVWPHLAWQWAAKALDPLRQEIYNLK
                     VDAILSGMWIALMGVNMLPAAALFMMMSMNLMGAGGRRLFTVGMGLLLASCLVTLQLT
                     GLPVAMRSSSLEVTLSLPVIMLYPLLFAWVSYQTAIKLAEHKRRLQAMSSRDGMTGVY
                     NRRHWEILLRNEFDHSRRHHREATLLIIDIDHFKSINDTWGHDAGDEAIIALTRQLQI
                     TLRGSDIIGRFGGDEFAVIMCGTPADSAITAMSRVHERLNTLRLPGAPQVMLRISVGV
                     APLTPQIGHYREWLKSADMALYKAKNAGRNRTEVAA"
     gene            complement(14851..>15126)
                     /gene="psiF"
                     /locus_tag="OPV72_002775"
     CDS             complement(14851..>15126)
                     /gene="psiF"
                     /locus_tag="OPV72_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate starvation-inducible protein PsiF"
                     /protein_id="HCR9915024.1"
                     /translation="LTAVGATEKPLTPQQQRMTTCNQQATAQALKGDARKTYLSDCLK
                     NSQSAPGEKSLTPQQQKMRECNVQATEQSLKGDDRSKFMSACLKKAA"
BASE COUNT         3527 a         4280 c         3998 g         3321 t
ORIGIN      
        1 atccgctggc ttatggaaag ttatacttac gaaaggcaat taatcactat ttttggcaat
       61 taaacgttcc ggcagcacaa agctaaatcg cgttcctttg ccaggcgaac tgtcgatttc
      121 aaggcggctt tcatggtgat tcaacgcatg tttcacaatc gccaatccca ggccgctgcc
      181 gcccgtttgc cgcgaacgcg ctttatcgac gcggtagaag cgttcggtca gacgaggaat
      241 atgctcggca gcaatccccg gaccgttatc ttgaatgcaa aattcagcgc catgcgcggc
      301 acgtcgccag ctcaccgtaa tatgcgttcc cgccggcgta tggtttactg cgttatatac
      361 caggtttgag atcgcgctac gtagctgctc ttcattgccc agaacgctaa gactatcgtc
      421 gaccgcaaac gtaaaggtat gtttctgctg gctgagcgtc tgcgcttcac gctccacgac
      481 ccgcagcatc atcggtacat ccactttttc atttaataac agcgccgggg ccacctcaat
      541 tttagacagc gtaagcagtt gttttaccag cccttccata cgatacgttt gctcgcgcat
      601 cgtatgcagc gctttctctc gcgtcgcccc ttccagcgcc tgttcctgca tcatttccag
      661 atagccttgc aataccgtca atggcgtacg caactcatgg ctaacgttgg cgaaaaagtt
      721 acgtctggcg ccttcaagct gatgcatttg cgtcacatcg cgcgccacca tcaggagttg
      781 tttatcggta taaggcatga cgcggatctc cagatgccgc ccggtattga gcaccaaatg
      841 aagcggacgg gtgaaatcac gcgtttttaa atactgggta aactccggat aacgcagtag
      901 attgagaata ttctgcccgt tgtcatccgg ccagcgtagc cccagtatct gttgcgccaa
      961 accgttacac caaaaaatgc cgccctcttc tgtggtcagt accacggcat caggcagcga
     1021 ctccgcgccg ctgcgaaaac gtttaatcag gttccccagc tcgcggcgac gcttcttatt
     1081 tcgcaactgc atctggtgta aaccgtataa cagcggttcc caacttcccc gccccggcgg
     1141 cggcgtcata cttctgtcga cccaaagcca ccaggagagg cgtaacaaat tccagaaatg
     1201 ccagacaagc agtcccgtca ccgccgccag taaaaaccac ggcagataac caaaaaaagc
     1261 gctaaggata agcgcgggga tgcaacagag caccagctcc agcaccagcc ttttccatga
     1321 cagccgttcc agcacgcgtc atactccctc aagaatggaa agccttctcc gccagaaacc
     1381 tgtgatcaac tggcggaaaa ggcattaaaa gcgggtcgaa aaacgatacc ctgtcccgcg
     1441 taccgtttgc accatccggt cgtggccgct gtgctccagc gccttacgca aacggcgaat
     1501 atgcacgtcg accgtccggt cttcaacgta cacattggtg ccccagacat gattgagcag
     1561 ctgttcgcgg ctgtaaaccc gttccgggtg cgtcataaag aaatggagta atttaaattc
     1621 ggtcggcccc atatccagcg ggctgtcgcc ggtcatcacg cggtgagagc caggatcaag
     1681 gctcagtccc tgcatctcga tcacctcttc gaccgccatc ggcgagatac gccgcataac
     1741 ggctttaatg cgcgccacca actccttggg ggaaaacggc ttggtaatgt aatcgtcagc
     1801 gccggtttcc agcccgcgca cacgatcttc ttcctcacct ctcgcggtca gcataaccac
     1861 aggaatatcc cgggtcatgg cctcacgttt gagatgttta ataaactgta accctgaccc
     1921 gccgggcaac atccagtcaa gaaggatgag atccggccag ggttcattaa gtttattcac
     1981 cgcactgtca taatcttcgg cttctacggg ctgaaagcca ttttgttcga gcacgaagca
     2041 caccatttca cggatcggcg cctcatcttc tacgaccaga atacgtctcg ccataatttg
     2101 ccctgttagt cgttagttat caatgccgcg ccattatgcg tcagatttat gacagattta
     2161 tgaaaaaaaa aggcggcatt gacagcatgt tgatgattta tgacaccggt gaaaccgtgc
     2221 attaccgtgt accggcggta aattgcgccc aaaaatggag gggatgacgt gtataatccc
     2281 gttcacgctt tttttgcatg gaacaattat gcgcatcctc cacacctctg actggcatct
     2341 gggacaaaac ttctacagta aaagccgcgc cgcggagcat caggcttttc tggactggct
     2401 gctggagacc gcgcaggccc atcaggtgga tgccattatt gtcgctggcg atatttttga
     2461 taccgattcg ccgccaagct atgcccgaga actttataac cgtttcgtcg ttaatttaca
     2521 gcaaacgggc tgtcatctgg tggtgctggc cggtaatcat gattccgtcg ccacgctaaa
     2581 cgaatcgcgc gacattctgg cgtttctcaa tacaaccgtg atcgccagcg cgggctatgc
     2641 gcctcggcta cttcatcgtc gcgacgggtc tccgggcgcc gtactgtgcc ccattccctt
     2701 tttgcgcccg cgcgacatta ttaccagtca ggcgggatta tccggcagcg agaaacagca
     2761 gcaacttctt catgcaattg ccgattatta tcaacagcag tatcaggaag cgtgcctgct
     2821 acgcggcgaa cgaaagctgc cggttatcgc aacgggacat ttaaccaccg tcggcgccag
     2881 caaaagcgat gcggttcgcg acatttatat cggtacgctg gatgcctttc cggcgcagca
     2941 tttcccccct gcggattata tcgcattggg acacattcac cgcgcgcaat gtgtcggcgg
     3001 cacagagcat atccgctatt gcggctcgcc catcgccctc agctttgatg agtgcggcaa
     3061 aagcaaatgc gtgcatctgg tgaccttcga ccagggaaaa tggcaaagta ccgaaagtct
     3121 ggctgtcccc gtgactcaac tgttggcggt tttaaaaggc gacctggcgt caattaccga
     3181 acagcttgag cagtggcgcg gcgttgagca atcgcccccc gtctggctgg atattgaaat
     3241 caccaccgat gattatctgc atgatatcca acgcagaata caggcattaa cggagtcact
     3301 ccccgtagag gtattactgg tgcgccgtag ccgcgaacag cgtgagcgct cgctggcgaa
     3361 cgagcggcgg gaaacattaa gcgagcttag cgtggaagag gtttttgcgc ggcgtctggc
     3421 gctggaagcg ttagataccc cgcagcgcga gcgcctgaat cagctctttt ccagcacgct
     3481 ctacgcgttg aatgaggagc atgaggcatg aaaattctca gtttgcgtct gaaaaacctg
     3541 aactcgctga aaggagaatg gaaggtcgac tttaccgccg aaccgtttgc cagtaacggg
     3601 ttattcgcca ttaccggccc gaccggcgcg ggaaaaacca ccttgcttga cgccatctgc
     3661 ctggcgctgt accacgaaac gccgcgcctg aatacggtat cgcaatcgca aaacgatttg
     3721 atgacgcgcg atacggcgga atgtctggcc gaagtggagt ttgaggtaaa aggcgaagcc
     3781 tggcgcgcgt tctggagcca gaaccgagcc cgaaatcggc ctgacggcaa tctccaggcc
     3841 ccacgcgtgg agctggcgcg gtgttcagac ggaaagatct ttgccgataa ggtaaaggat
     3901 aaactggaga tgatcgccac gttgaccggg ctggactacg ggcgcttcac ccgttcaatg
     3961 ttgttatcac aggggcagtt cgccgccttt cttaacgcca aagcgaaaga gcgcgcagag
     4021 cttctggagg agctcaccgg cactgagatt tacgggcaga tctccgcaca ggtatttgaa
     4081 aaacataaat cagcccgtct cgaactggaa aagttacaag cgcaggccag cggcgtcgcc
     4141 ctattggcgg acgaacagtt acagcaactg gaagccagtt tgcaggcgct tactgacgaa
     4201 gagaaacgcc tgctggccga ccagcaggga cagcagcagc accttcactg gctgacccga
     4261 aaaaacgagc tccacactga attacacgcc cgacagcagg cgctgtacgc ggcgcaagag
     4321 gcgcgagaaa aagcgcagcc gcagctcgcg gcgctgacgc tggcgcaacc tgctcgccag
     4381 ttgcgtccgc attgggagcg cattcaggaa caaacccgcg ccgttgagcg tgttcgccag
     4441 cacagtgatg aagtgaatgc tcgcttacaa agcgcgtatc gcctgcgcca gcgtatccgc
     4501 gcctgcgcgc atcgacaatt cacgcaactg aacgccacag ggcagcggtt gaagacatgg
     4561 ctggcggaac acgacggcat ccgcgtctgg cgcagcgaac tggcggggtg gcgagcatta
     4621 ttaacacaac aatcccacga ccgggcgcaa ctgagccaat ggcaacagca gttgctgagc
     4681 gatatgcgtc agcgtgatgc gctaccgccg ctcacgctcg acctcacgcc acaggcgctg
     4741 gcggaagcca gggcattgca tacccggcag cgtccgctac gccatcgtct cgccgcgctt
     4801 caggggcaaa ttctcccgaa acaaaagcgt caggcgcagc tacaggcagc tatcgcgcgt
     4861 catcatcagg agcagacgca atacacccaa cgtctggcag ataagcgcct gagttataag
     4921 actaaagcgc aggagcttgc ggacgttcgc actatttgcg agcaggaggc gcgcatcaaa
     4981 gatctggaaa gccagcgggc gcacttacag tccggccagc cgtgtccgct ttgcggctcg
     5041 acgacgcacc ccgccatcgc cgcctatcag gcgctggaac tgagcgcgaa tcaaacccgc
     5101 cgcgacgcgc tggaaaaaga ggtcaaaacg ctggcggaag aaggcgctgc gctgcgagga
     5161 cagttagatg ccttaacgca acaattacag cgggatgaaa gcgaggcgca gtcgttgttg
     5221 caggaggagc aagcgcttac tgaggaatgg caaacgctgt gcgctacgct gggcgttcag
     5281 ctccagccgc aagaagacct cgctggctgg ctgaccgccg cggaagagca tgagcaacag
     5341 ttggatcagc tcagccagcg tcatgctcta caaacgcaaa tcgcggcgca tactgaacag
     5401 gtagcgcgct ttaccgcgca gattgcacag cgtcaggcgt cgctgacggc tgatttggcg
     5461 cagtatacgc tttcccttcc tgcgccagaa gacgaggcat cctggctgaa tgagcgcgcc
     5521 gacgaagcga aaatatggca acagcgtcag acagagttcg cggatttgca aacgcagatc
     5581 gacaggcttg ccccgttgct ggagacgcta ccgcaaacgg ataccgcgga ttccgacgac
     5641 gacgtgccgc tggataactg gcggcagacg catgatgagt gcgtgtcatt acaaagccag
     5701 ttgcaaaccc tgcaggaaca gacgacgcag gaacagcagc gcgccgccga ggcgatagcg
     5761 cactttgatg cggcgttaaa aaatagcccg tttgacagcc aggcaacgtt cctggcggcg
     5821 ttgctggatg aagagaccgt gacccgtctg gaaaaacaac aacaaacgct ggaaagtcag
     5881 ctacaacaag cgaaggcgtt aagcgcgcag tccgcgcagg cgctggctga ccatcagcaa
     5941 cagccacccg ccggtctgga cccaacgtgt acggcggagc agctcgcgca gcggctggcg
     6001 cagttggcgc aacaactgcg cgagaacacg acacgccagg gggaaatccg ccagcaaatt
     6061 aaacaggatg cagataatcg gcagcgccaa cgggcgctga tggcggaaat gaagcaagcc
     6121 tctcagcaag tggaagactg gggctatctc aatgcgctga tcggctctaa agaaggtgat
     6181 aagttccgca aattcgccca gggactgacg ctggataatc tggtctggct ggcgaatcat
     6241 cagctcaccc gcctgcatgg ccgctattta ttgcagcgca aagccagcga cgcgctggaa
     6301 ctggaggttg tcgatacctg gcaggccgac gccgtgcgcg atacgcgaac gttatcaggc
     6361 ggcgaaagct tcctggtcag cctggcgctg gcgctggcgt tatcagattt ggtcagccat
     6421 aaaacgcgca ttgattcctt gttcctggac gaaggcttcg gcacgcttga tagcgaaacg
     6481 ctggacgccg cgctggatgc gctcgacgcg ctgaatgcca gcgggaagac catcggtgtg
     6541 attagccacg tggaagccat gaaagaacgt atccccgtgc agataaaagt gaaaaaaaat
     6601 caatgggctt ggttatagca aactggacaa agcgtttgcc gtggagtaac gcgagtgtca
     6661 tcctgcgcac agcataccgt catgacatag cataataatg aatacacaaa gacgaataag
     6721 gaatggtatt acctcgcgct tatccgcaag ctatacgttg attggctgtg acaattcata
     6781 gccacagcgc gcgacatgcg tcttcatttt cggcaggtgg tatgaaaaaa gttatttttt
     6841 ctttggcgct gggtacgttc ggactgggga tggccgagtt tggcattatg ggcgtgctga
     6901 cggagctggc acgcgatgtc gggataacga ttcccgccgc cgggcatatg atctcgtttt
     6961 acgccttcgg cgtcgtgctg ggcgcgcctg taatggcgct cttttccagc cgcttttcgc
     7021 ttaaacatat actgctgttt ctggtcatac tgtgcgtgat gggcaatgcc atatttacct
     7081 tttcctcgtc atatctgatg ctcgccgtcg gcagactggt ttccggcttt ccacacggcg
     7141 ccttttttgg cgtcggtgcc attgtcttgt caaagattat ccgccccggg aaggtcaccg
     7201 ccgccgtcgc gggtatggtt tcagggatga cggtggcgaa tctggtgggc attccgttcg
     7261 gcacttacct gagccaggaa tttagctggc gctacacctt tttattgatc gcggttttca
     7321 acatcgccgt gctcaccgcg attttcttct gggtgccgga tattcgcgac aaagcccaag
     7381 gcagcctgcg cgagcagttc cacttcttgc gtagccccgc gccgtgactc attttcgccg
     7441 ccacgatgtt cggcaatgcg ggcgtttttg cctggttcag ctatatcaag ccatttatga
     7501 tgtacatctc cggtttttcg gagacgagca tgacgtttat tatgatgctg gtcgggctgg
     7561 ggatggtgtt aggcaatctg ttaagcggca aactctccgg tagatatacg ccgctgcgca
     7621 tcgcggtagt gactgacctc gttatcgtgc tctctctcat ggcgctcttt ttcttcagcg
     7681 gatacaaaac ggcatcgctg actttcgcgt ttatctgctg tgctggtctg tttgcgctct
     7741 ctgcgccgct gcaaatcctg ctgctgcaaa acgccaaagg cggcgaactg ctgggcgcgg
     7801 cgggagggca aatcgcgttt aatctcggta gcgcgattgg cgcctggtgc ggcgggctga
     7861 tgctgacgct aggttttgcg taccactatg tggcgcttcc cgccgccctg ctctcgtttt
     7921 ccgccatgtc gtcgttgctg gtatacggac gtctaaaaca caagcagcca tcggtcacgc
     7981 cggttgccgg atgacgccat ccggctagaa acgttacgcc agcggccaca gccaggccgc
     8041 gccgcgcacg ccgctcgaat cgccatgccg cgccttacgt accggcgtct cgcactcgcc
     8101 gccaaaaaca aacgatttca tcagcgacgg aaccgttttg tacaggcgct caacattgct
     8161 cataccgccg cccagcacaa tgacatccgg atccagaata ttcacgacat gagataatgc
     8221 cttcgccagc cgtagctcat aacggcttat cgccagttcc gccacggcgt cctgcgcgtc
     8281 gaccagacga ataatctcat cgccttttag cgttttaccg ctcaaacgct ggtaatccgt
     8341 ggcgaatccc gtaccggaaa taaaggtttc gatacagcct tgtttaccgc aataacaggg
     8401 aatttcttcg cggtaacgca actcatcgtc atccatccac ggcaacggat tgtggcccca
     8461 ttcgcctgcc gtaccgttgc cgccgatgtg cgcccggcca tttagcgcta cgcccgcgcc
     8521 gcacccggta ccgataatca ccgcaaatac cgtttgcgcc cccgccgccg cgccatctac
     8581 cgcctctgat accgccaggc aattggcatc gttggctaac cgcacttcac gcttcagacg
     8641 acggctcaca tcgctatcga acggctggcc gttaagccac gtagagttag cgttttttac
     8701 cacgccggtg taaggcgaga gagaaccggg aatgccaatg ccaacgctac cggtctggcc
     8761 ggtcgcctgt tccgccatgt cgaccagcgt agcgatggtt tctatcgttt gctgataatc
     8821 ctcccgcggc gtaggcagac gatggcgaaa ccgctgctct cctgcatcat caagcgcaat
     8881 gacttccgtt tttgtgccgc ctaaatcgat accaatacgc acataccgct cctcattttt
     8941 tgggaatatc aacagggtag aattcaccgt tctgattggc aatgcaagcc tgccgacaat
     9001 tcgttactat accgactgga tttaacgaca aggccgtgga aattatcatg ctgtggttca
     9061 aaaatttaat ggtttaccgt cttagccgcg atatcacatt acgcgccgaa gagatggaga
     9121 aacagctcgc ctcaatgacg tttaccccat gcggtagcca ggatatggcc aaaatgggct
     9181 gggttccgcc gatgggctct cacagcgatg cgttaacgca caccgccaat ggccaaatta
     9241 ttatttgcgc gcgcaaagaa gagaaaatcc tgccatcgcc agtgatcaaa caggcactgg
     9301 aggcgaaaat ccagaaactg gaagccgatc agggacgcaa gctgaagaag acggaaaaag
     9361 attccctgaa ggatgaagtg ttgcattcgt tgctgccgcg cgcgtttagc cgcttcagtc
     9421 agacaatgat gtggattgat accgttaacg gcctgattat ggttgactgc gccagcgcga
     9481 aaaaagcgga agatactttg gcgctactgc gtaaaagtct tggctcgctg ccggtcgtcc
     9541 cgctggcgct ggaaaatccg attgagctga cgctcaccga gtgggtgcgc tccggtacgg
     9601 tcgctcaggg tttccagttg ctggacgaag ccgaattgaa agcgatgctg gaagatggcg
     9661 gcgtgatccg cgcgaaaaag caggatctgg tcagcgacga gatcgccgtt catattgaag
     9721 cgggtaaagt ggtcacgaag ctggcgctcg actggcagca gcgtattcaa ttcgtcatgt
     9781 gcgacgacgg ctccattaag cgtctgaaat tctgcgatga gctgcgcgat cagaacgaag
     9841 atatcgaccg ggaagatttt gcccaacgtt ttgatgcgga ctttatcctg atgaccggcg
     9901 agctggcggc gctgattcaa agcctggtgg aaggattagg cggcgaagcg cagcgctaac
     9961 cagagggtcc ctctccgccg gagaggggac tcaccgttac aaatagcggc acagatacga
    10021 ggtgggctca gcgacctgta gatgaaactc gctgtggcca ggcacgttaa acacctcacc
    10081 ggctgtatac actttccatt cgacagttcc cggcaacagt accttcaacg cgccgctcac
    10141 aaccgtcatc tcttcgggtt cggcggtgcc aaatgtatac tccccttccg ccatcacacc
    10201 aacgctggcc cggccggtgc tactgctggt aaatccaata gacttcactt tcccggaaaa
    10261 gtattcattg ctttgtagca taatcaggcc ccgtctcatt attaaattaa cacccaatat
    10321 agagtcctga cgttcggcct gtcacgtaaa attagacaag cagttctgaa gctaaccgcg
    10381 caatcaaaac attagagagt aaaaccggca catccagcgc ctgctgtaaa atatcccgat
    10441 gacgctgatg aaaacccaga caatccagca taatgacgtc cgcgccttga tccagtagcg
    10501 cctgcccggc atcaattaac tgttgctcag aaccgtgaac cggattcgcc agcgaataca
    10561 ccggcggcat ttgcaatacc tgccattttt tctcctgggc cgccagaagt tctgcaacag
    10621 gcacaatcgc gcccacctga tgtccatcca caatagaggc gacaagcggt ggaataatac
    10681 gcagcggttc aagcaaaata gaattacggg ctgccgtact tttaatcgcc gcggtgctca
    10741 tcagtataat gacatcgtaa ccctgattat ccagcacctc gacaacgctc tgtaaatctc
    10801 gctccacttt ctggcgggaa acatgggcta tctggttatc attcagcaac gtcaaaagca
    10861 gatcgtcgcc aggctctaca gcgtaatccg ccataacgtc ttcccggctc atttttccca
    10921 gcaggctatg atgggttatg tgttgttcgt cgatgtattc cgtcagaagc ggtaacactt
    10981 cgctcattgg cacaacgccg attgtgagga ttgccaacga cgcactcatt tttattccac
    11041 cttattactt cgtcgtaatt cccgggcaaa tattcacacg ctcaccgcgc tacctgccct
    11101 acaaatctca gaaagcgtag cagcagatga gcaacgtatt gtgtaaagat tccaaataac
    11161 tccaatattg tattgttatc gcttaattta tggttttagt tgccagtata aatgtttcaa
    11221 gaatgtgatg gagatacaat ttaggggtac tcagaatccc ttccgagtgg ttcatgcgtc
    11281 tatgatttat ccggatcttc gtaacgtttt ttcgcatcca tcgcttcttc tgcggtcgga
    11341 tgctcgctga tgagcgaatc aggtttcgga tggtcagccc gtagctgata ccacgtcacc
    11401 gtctggcccg gcgtgccttt ttcaatggtg acgatataag cttcccgcgg ataaggtggt
    11461 ctggttggca tagcgtttcc tttattctgg gtgagcgtta agtatagaca tctccctgta
    11521 accgttgcgt cgacggcggc agcgccgcaa taatttcaga aacgacctgg gccggcgctt
    11581 tcgtcgcgtc aataatgtaa tgcgccgttt cgcgatacaa cgcgtcacgc tgctcaagca
    11641 cttcccgaac ctcttcgctc aacggcttgc cggtgagggt cgggcgcaga tccgcttcag
    11701 gttcagcctc aagccggtta accagcgtgg ataccggcgc gcacagataa atcactacgc
    11761 caacacggtg catataacgt cggttatact ccgtgagaat aataccgcct cccgtcgcca
    11821 cgacagtcga aggcgcgctt accgcctcca gggccgcggt ttcccgggcg cggaaccctc
    11881 cccagccttc tttttcaacg atatcagcga cgctcatctg cacgtgcgat tgcagccagc
    11941 ggtcggtatc tgcaaaccga aaaccggttg cctgcgccag cgccataccg atggtggttt
    12001 tcccacagcc ccgcgggcca acaagataaa gaggttgcat catagcaggc gttcccccag
    12061 gaactgcgca tacgcaggat ttgatatcag taatgttata atcatatcat ctaactagta
    12121 caacgcataa atgtaaataa taatttacac aaaggtacta aagtcacaat attagtacta
    12181 tagcaagaat cagaaatgaa taaactgtaa atttttcatt acatgattta ttttttacgc
    12241 tggctttcca gccaccactt atccagctcg gcggcaaaat gctgacgatc gcgcggcgag
    12301 agagtgtttg gtccccccgt ttgtacgccg ctggcgcgta gcgtgtccat aaagtcacgc
    12361 atcgtcagac gttcgcgaat cgtggcgtcg ctatagcgtt ctccccgggg attaagagcc
    12421 gcagcgcctt tttccagcac ttcagccgcc agcggaatat ccgcggtaat caccagatcg
    12481 cccgcttcgc attgacgcac aatttcattg tccgccacgt caaacccggc ggccacgcga
    12541 agcgtgcgga taaaacgcga aggcggcacg cgcaaggcct gattggcaac cagaataagc
    12601 ggcaactgca tccgctcggc ggcgcggtac aaaatttctt taatgacatt cggacacgca
    12661 tccgcatcca cccagatggt cataatgtct cccgtacggt atacaatctt ttattgtctc
    12721 gcgcttttgt ctttcatcaa agtgctgttt ctccttctgc ccgttttcaa tccgcgttaa
    12781 gctaaccatt ccccataaca cacaaacata gggagtgacg agatggagaa gaaaatcggt
    12841 tttattggct gcggtaatat gggcaaggct attcttggcg gactgattgc cagcggtcag
    12901 gtacttcccg gccagatctg ggtctacacc ccctcccccg ataaagttgc cgccctgcat
    12961 gatcagtacg gcattaatgc ggcgcaaagc gcgcaggagg tcgctcaggt cgcggatatc
    13021 gttttcggcg cggtaaaacc gggcattatg gtgaaagtgc tcagtgaaat ctcctccagc
    13081 ctgaacaaag actcgctggt ggtctctatc gccgcaggcg taacgcttga tcagcttgcg
    13141 cgcgcgctgg gacacgaccg taaaatcatt cgcgctatgc cgaatacgcc gtcgctggtc
    13201 aacgcaggaa tgacctccgt cacgcccaac gcgctggtca caccggaaga tacggctgat
    13261 gtgctgaata ttttccgctg ctttggcgag gcggaagtga ttgctgagcc gatgatccat
    13321 ccggtggttg gcgtgagcgg atcttcgccg gcctatgtct ttatgtttat cgaggcgatg
    13381 gcggacgctg ccgttctggg cggtatgcct cgcgctcagg cttataaatt cgccgcgcag
    13441 gccgtcatgg ggtcggcgaa aatagtactc gaaaccggaa agcatcccgg cgaactgaaa
    13501 gatatggtgt gctcgcctgg cggaacgacg attgaagccg tacgcgttct ggaagaacgt
    13561 ggcttccgcg ctgcggtaat agaagcgatg acgaaatgta tggaaaaatc agaggcgctc
    13621 agtaaatcct gaagcccggc tggacgtcat gccgccactt cggtgcggtt acgtccggca
    13681 ttctttgctt tgtaaagcgc catatccgca gactttaacc attcccgata atgaccgatt
    13741 tgtggcgtta acggcgccac gcccacgctg atacgtaaca tgacctgcgg cgcgcccggc
    13801 aagcgtaagg tatttagccg ttcatgcact cgcgacatgg cggtaatcgc gctgtctgcc
    13861 ggcgttccgc acataatcac cgcaaattcg tcgccgccaa agcgcccgat aatatcactc
    13921 ccgcgtagcg ttatctgtaa ttgacgcgtc agggcgataa tagcctcatc cccagcatca
    13981 tgtccccagg tgtcgttaat gctcttaaaa tgatcgatat cgataatcaa caatgtcgcc
    14041 tcccgatggt ggcgtcggct gtgatcgaat tcattacgta ataaaatttc ccagtggcgt
    14101 cggttataga cgccggtcat gccatcccgc gaactcatcg cctgcaagcg tcgcttatgt
    14161 tccgctaatt taatggccgt ttgataactt acccaggcga acagaagcgg atacaacata
    14221 atgacgggca aagagagcgt gacttccagc gacgagcttc gcatcgcgac gggtagcccg
    14281 gtaagctgca acgtcaccag acatgacgcc agcaaaaggc ccattccgac agtgaatagc
    14341 cgccgcccgc cagcgcccat cagattcatg ctcatcatca taaacagcgc ggcggcaggc
    14401 aacatattga cgcccatcaa cgcgatccac atgccggaga ggatcgcatc cactttcagg
    14461 ttgtaaattt cctggcgtag cggatcaagg gctttcgccg cccactgcca cgccagatgc
    14521 ggccagacaa aagaccagcc gaccagcaat aaccaccagc cgccaaagac aggttgcgac
    14581 actaacacgg cggccaccgg taaaagcatc ccccctaacc ccaccgcgcg cggtagcctg
    14641 atgcgccggg cgaagcgcaa tccggagcgc tgacgatcat cagaagggtc aggcggcgct
    14701 accgcctgct caaccgcttt tcggtaaaaa ttttcatcat tcattatttt tgggaacatt
    14761 tagaaacaat tttcccaaat tatagaaaca gagcgcatgg agggagtatg aaatttcggg
    14821 tgagtgtttt tcagggctca cccgatagca ctacgccgct tttttcaggc aggcgctcat
    14881 aaacttgcta cggtcatcgc ctttcagtga ttgttccgtc gcctgaacat tgcattcacg
    14941 cattttctgc tgttgcggcg tcaggctttt ctcgccaggg gctgactggc tgtttttcag
    15001 gcagtcgcta aggtaggttt tacgcgcatc gcctttcaac gcttgcgctg tcgcctgctg
    15061 attacaggtc gtcatgcgct gctgttgcgg cgttaacggt ttctcggttg cgccgacggc
    15121 ggttaa
//
LOCUS       DAJVBX010000108        14839 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.108, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000108 DAJVBX010000000
VERSION     DAJVBX010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 14839)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14839)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14839
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.108"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            287..1501
                     /gene="alaA"
                     /locus_tag="OPV72_002776"
     CDS             287..1501
                     /gene="alaA"
                     /locus_tag="OPV72_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine transaminase AlaA"
                     /protein_id="HCR9915025.1"
                     /translation="MSPIEKSSKLENVCYDIRGPVLKEAKRLEEEGNKVLKLNIGNPA
                     PFGFEAPDEILVDVIRNLPTAQGYCDSKGLYSARKAIMQHYQARGMRDVTVEDIYIGN
                     GVSELIVQAMQALLNSGDEMLVPAPDYPLWTAAVSLSSGKAVHYLCDESSDWFPDLDD
                     IRAKITPRTRGIVIINPNNPTGAVYSKELLMEIVNIAREHNLIIFADEIYDKILYDDA
                     EHHSIAALAPDLLTITFNGLSKTYRVAGFRQGWMVLNGPKKHAKGYIEGLEMLASMRL
                     CANVPAQHAIQTALGGYQSISEFILPGGRLYEQRNRAWELINDIPGVSCVKPRGALYM
                     FPRIDAKRFNIHDDQKMVLDFLLQEKVLLVQGTAFNWPWPDHFRIVTLPREDDLEMAI
                     NRFGRFLSGYHQ"
     gene            1595..2194
                     /gene="yfbR"
                     /locus_tag="OPV72_002777"
     CDS             1595..2194
                     /gene="yfbR"
                     /locus_tag="OPV72_002777"
                     /EC_number="3.1.3.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-deoxynucleotidase"
                     /protein_id="HCR9915026.1"
                     /translation="MKQSHFFAHLSRMKLINRWPLMRNVRTENVSEHSLQVAMVAHAL
                     AAIKNRKFGGQLNAERIALLAMYHDASEVLTGDLPTPVKYFNSQIAQEYKAIEKIAQQ
                     KLVDMAPDELHDIFAPLIDENAWSKEEQAIVKQADALCAYLKCLEELSAGNNEFRLAK
                     TRLEKTLELRRSQEMDYFMAVFVPSFHLSLDEISQDSPL"
     gene            complement(2286..4112)
                     /locus_tag="OPV72_002778"
     CDS             complement(2286..4112)
                     /locus_tag="OPV72_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HCR9915027.1"
                     /translation="MNGELIWVLSLLAIAVVLFATGKVRMDAVALFVIVAFVLSGTLT
                     LSEAFSGFSDPNVILIAALFIIGDGLVRTGVATVVGTWLVKMAGSSEIKMLVLLMITV
                     AGLGAFMSSTGVVAIFIPVVLSVSMHMQTSPSRLMMPLSFAGLISGMMTLVATPPNLV
                     VNSELLREGLHGFNFFSVTPLGVVVLALGIVYMLVMRFMLKGDAPGQQAGKRRTFRDL
                     IREYRLTGRARRLAIRPGSPMVGQRLDDLKLRERYGANVIGVERWRRFRRVIVNVNGV
                     SEFRARDVLLIDMSAAEVDLREFCAEQLLEPMVLRGEYFSDQALDVGMAEISLIPKSE
                     LIGKSVREIAFRTRYGLNVVGLKRDGVALEGSLADEPLLMGDIILVVGNWKLISLLGQ
                     KGRDFVVLNMPVEVSEASPAHSQAPHAIFCLVLMVALMLTDEIPNPSAAIIACLLMGK
                     FRCIDAESAYKAIHWPSIILIVGMMPFALALQKTGGVSLVVQGLMDIGGGYGPYMMLG
                     CLFVLCAVIGLFISNTATAVLMAPIALAAAKSMGVSPYPFAMAVAMAASAAFMTPVSS
                     PVNTLVLGPGNYSFSDFVKLGVPFTLIVMAVCIVMIPMLFPF"
     gene            complement(4188..4865)
                     /locus_tag="OPV72_002779"
     CDS             complement(4188..4865)
                     /locus_tag="OPV72_002779"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461276.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphatase"
                     /protein_id="HCR9915028.1"
                     /translation="MPEEAHVQCKGFLFDLDGTLVDSLPAVERAWCSWADRFNLAHDE
                     VLGFIHGKQAITSLRHFMAGKSEAEIAAEFTRLEQIEATETAGITALPGAVDLLNHLN
                     KAGIPWAIVTSGSMPVARARHQVAGLPAPEVFVTAERVKRGKPEPDAYLLGAQLLGLA
                     PQECVVVEDAPAGVLSGLAAGCHVIAVNAPADTPRLADVDFALDSLTQLSVAKQPNGD
                     VVVLRKT"
     gene            complement(4858..5352)
                     /locus_tag="OPV72_002780"
     CDS             complement(4858..5352)
                     /locus_tag="OPV72_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007371080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbU family protein"
                     /protein_id="HCR9915029.1"
                     /translation="MEMTNAQRLILSNQYKMMTMLDPTNAERYRRLQTIIERGYGLQM
                     RELDREFGELTEETCRTIIDIMEMYHALHVSWTNLKDTQAIDERRVTFLGFDAATEAR
                     YLGYVRFMVNIEGRYTHFDAGTHGFNAQTPMWEKYQRMLNVWHACPRQYHLSANEINQ
                     IINA"
     gene            complement(5435..5890)
                     /locus_tag="OPV72_002781"
     CDS             complement(5435..5890)
                     /locus_tag="OPV72_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF412 domain-containing protein"
                     /protein_id="HCR9915030.1"
                     /translation="MSTPDNRSVNFFSLFRRGQHYAKTWPMEKRLAPVFVENRVIRMT
                     RYAIRFMPPVAVFTLCWQIALGGQLGPAVATALFALSLPMQGLWWLGKRSLTPLPPSI
                     LNWFYEVRGKLQEAGQALAPVEGKPDYQALADTLKRAFKQLDKTFLDDL"
     gene            6230..7432
                     /gene="ackA"
                     /locus_tag="OPV72_002782"
     CDS             6230..7432
                     /gene="ackA"
                     /locus_tag="OPV72_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HCR9915031.1"
                     /translation="MSSKLVLVLNCGSSSLKFAIIDAVNGDEYLSGLAECFHLPEARI
                     KWKMDGSKQEAALGAGAAHSEALNFIVNTILAQKPELSAQLTAIGHRIVHGGEKYTSS
                     VVIDESVIQGIKDSASFAPLHNPAHLIGIAEALKSFPQLKDKNVAVFDTAFHQTMPEE
                     SYLYALPYSLYKEHGVRRYGAHGTSHFYVTQEAAKMLNKPVEELNIITCHLGNGGSVS
                     AIRNGKCVDTSMGLTPLEGLVMGTRSGDIDPAIIFHLHDTLGMSVDQINKMLTKESGL
                     LGLTEVTSDCRYVEDNYATKEDAKRAMDVYCHRLAKYIGSYTALMDGRLDAVVFTGGI
                     GENAAMVRELSLGKLGVLGFEVDHERNLAARFGKSGFINKEGTRPAVVIPTNEELVIA
                     QDASRLTA"
     gene            7509..9653
                     /gene="pta"
                     /locus_tag="OPV72_002783"
     CDS             7509..9653
                     /gene="pta"
                     /locus_tag="OPV72_002783"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HCR9915032.1"
                     /translation="MSRIIMLIPTGTSVGLTSVSLGVIRAMERKGVRLSVFKPIAQPR
                     AGGDAPDQTTTIVRANSTLPAAEPLKMSHVESLLSSNQKDVLMEEIIANYHANTKDAE
                     VVLVEGLVPTRKHQFAQSLNYEIAKTLNAEIVFVMSQGTDTPEQLNERIELTRSSFGG
                     AKNTNITGVIINKLNAPVDEQGRTRPDLSEIFDDSSKAQVIKIDPAKLQESSPLPVLG
                     AVPWSFDLIATRAIDMARHLNATIINEGDIKTRRVKSVTFCARSIPHMLEHFRAGSLL
                     VTSADRPDVLVAACLAAMNGVEIGALLLTGGYEMDARISKLCERAFATGLPVFMVNTN
                     TWQTSLSLQSFNLEVPVDDHERIEKVQEYVANYVNADWIESLTATSERSRRLSPPAFR
                     YQLTELARKAGKRVVLPEGDEPRTVKAAAICAERGIATCVLLGNPDEINRVAASQGVE
                     LGAGIEIVDPEVVRESYVARLVELRKSKGMTEPVAREQLEDNVVLGTLMLEQDEVDGL
                     VSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPEQVYVYGDCAINPDPTAEQLA
                     EIAIQSADSAIAFGIEPRVAMLSYSTGTSGAGSDVEKVREATRLAQEKRPDLMIDGPL
                     QYDAAVMADVAKSKAPNSPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQGM
                     RKPVNDLSRGALVDDIVYTIALTAIQASQQQQ"
     gene            9871..11391
                     /gene="yfcC"
                     /locus_tag="OPV72_002784"
     CDS             9871..11391
                     /gene="yfcC"
                     /locus_tag="OPV72_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HCR9915033.1"
                     /translation="MSVVTESKTARKWAMPDTLVIIFFVAILTSIATWVVPVGMFDSQ
                     EVQYQVDGQTKTRKVVDPHSFRIVTNEAGEAQYHRVQFFTTGDERPGLMNFPFEGLTS
                     GSKFGTAVGIIMFMLVIGGAFGIVMRTGTVDNGILALIRHTRGNEVLFIPVLFVLFSL
                     GGAVFGMGEEAVAFAIIIAPLMVRLGYDSITTVLVTYIATQIGFASSWMNPFCVVVAQ
                     GIAGVPVLSGSGLRIVVWIVATLIGLVFTLVYASRVKKNPLLSRVHESDRYFREQQDE
                     VVQRPFTFGDWLVLLVLTGVMIWVVWGVIVHAWFIPEIASQFFTMGVVIGLIGVIFRL
                     NGMTVNVMASSFTEGARMMIAPALLVGFAKGILLLVGNGEAGEPSVLNTLLNSIAHGI
                     SGLNNAIAAWFMLLFQAVFNFFVTSGSGQAALTMPLLAPLGDLVGVNRQVTVLAFQFG
                     DGFSHIIYPTSASLMATLGVCRVDFRNWLKVGASLLGLLFIMSSVVVIGAQMMGYH"
     gene            complement(11440..12393)
                     /locus_tag="OPV72_002785"
     CDS             complement(11440..12393)
                     /locus_tag="OPV72_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HCR9915034.1"
                     /translation="MIKLAPAGLKDDIEMRKVYAGFVAGQIEAGSPIIALEADLMSSM
                     AMDSVARDYPQHVINCGIMEANVIGTAAGLALTGRKPFVHTFTAFASRRCFDQLFMAL
                     DYQRNNVKVIASDAGVTACHNGGTHMSFEDMGIVRGLAHSVVLEVTDAVMFANILRQL
                     MDLDGFYWLRTIRKQATSIYAPGSTFTIGKGNVLREGDDITLIANGIMVAEALEAARQ
                     LEQEGVSAAVIDMFTLKPIDRMLVKNYAEKTRRIVTCENHSIHNGLGSAVAEVLVENC
                     PVPMRRVGVKERYGQVGTQDFLQQEYGLTAAAIVEAAKSLL"
     gene            complement(12386..13216)
                     /locus_tag="OPV72_002786"
     CDS             complement(12386..13216)
                     /locus_tag="OPV72_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HCR9915035.1"
                     /translation="MNVTEITQLARDIRVATLKSLNHLGFGHYGGSMSVVETLAVLYG
                     AVMKIDPADPDWPERDYFVLSKGHAGPALYSTLAIKGYFPREELNTLNQNGTRLPSHP
                     DRLKTHGVDATTGSLGQGISIAGGMALSHKLARRPNRVFCIVGDGELNEGQCWEAFQF
                     IAHHRLNNLTVFIDWNKQQLDGELEEIINPFDLEGKFRAFGFDVVTVKGDDIAGLLAV
                     VQPVPPADARPRVVILDSIKGQGVPCLEQLTNSHHLRLTDGMKQTLNEAIHQLEVMHD
                     "
     gene            complement(13213..14604)
                     /locus_tag="OPV72_002787"
     CDS             complement(13213..14604)
                     /locus_tag="OPV72_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461284.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HCR9915036.1"
                     /translation="MFILETLNFVVDILKVPSVLVGLIALIGLVAQKKAFSDVVKGTI
                     KTILGFIVLGGGATVLVGSLNPLGGMFEHAFNIQGIIPNNEAIVSIALEKYGASTALI
                     MAFGMVANIVVARFTRLKYIFLTGHHTFYMACMIGVILTVAGFEGVGLVFTGSLILGL
                     VMAFFPALAQRYMRRITGTDDIAFGHFGTLGYVLSGWIGSLCGKGSRSTEEMNLPKNL
                     SFLRDSSISISLTMMIIYLIMAVSAGREYVEATFSGGQNYLVYAIIMAITFAAGVFII
                     LQGVRLILAEIVPAFTGFSEKLVPNARPALDCPVVYPYAPNAVLIGFLFSFLGGLVGL
                     FLLGQMKLVLILPGVVPHFFTGATAGVFGNATGGRRGAMIGAFANGLLITFLPVLLLP
                     VLGAIGFANTTFSDADFGVIGILLGNLARYLSPMAITGLVVALFALLVAYNVLAKSKK
                     ATAEVQENSGAKE"
     gene            complement(14625..>14839)
                     /locus_tag="OPV72_002788"
     CDS             complement(14625..>14839)
                     /locus_tag="OPV72_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCR9915037.1"
                     /translation="IKKVLKKLNIDAEVEHSDLSSATPGAADLFVMAKDIAASASVPE
                     SQLVVINNIIDINELETQLRAWFAKQ"
BASE COUNT         3596 a         4186 c         3765 g         3292 t
ORIGIN      
        1 cgacactaat gatgaatgct tatctctcat aaaacagata atttctgaca acataaaaaa
       61 ccacattacg cgcaaccaca tagaacaaaa cactatacat acagacaaaa atagaaaatg
      121 catctaacca aatgatttta tgaagtttta aacagtacga aagcgcgtta aaaataaaca
      181 aaatcttctt ctgttcactc ttcaaaactc accgtcgtgg gagtacattg tttcgtgctg
      241 acttccacgg cagggagtgg caataacagc taaaaggtca agattcatgt cccccattga
      301 aaaatccagc aaactcgaaa atgtctgtta tgacattcgt ggccccgttc tgaaagaagc
      361 gaaacgcctt gaggaagaag gtaataaagt tcttaaactg aatatcggca accccgcccc
      421 cttcggattc gaagcgccgg acgaaattct ggtcgatgtc attcgtaatt tgccgacggc
      481 gcaaggatat tgcgactcga aagggcttta ttccgcccgt aaagcgatta tgcagcatta
      541 tcaggcccgt ggaatgcgcg atgtaaccgt ggaagatatc tatatcggta acggcgtttc
      601 cgagctgatc gttcaggcga tgcaggcgtt gcttaacagt ggcgatgaaa tgctggttcc
      661 cgcgcccgat tatccgttat ggacagcagc ggtatcgctc tccagcggca aggcggtaca
      721 ttatctttgc gatgaatctt ccgactggtt cccggacctt gacgatatcc gcgccaaaat
      781 caccccacgt acgcgtggta ttgtcattat taatccaaac aaccctactg gcgccgtcta
      841 ttctaaagaa ttgttgatgg aaattgtcaa cattgcgcgc gagcataatc tcatcatctt
      901 cgccgatgaa atttatgaca agattctcta tgacgatgcc gaacatcact ctatcgccgc
      961 actggcgcct gatctgctga ccatcacctt taatggtttg tctaaaacct atcgcgtcgc
     1021 cggcttccgc cagggctgga tggtgctgaa cgggccgaaa aaacatgcga aaggctatat
     1081 tgaagggctg gagatgttag cctcaatgcg cctgtgcgcc aacgtcccgg cgcaacatgc
     1141 tattcagacc gcgctcggcg gctatcaaag cattagcgaa tttattctgc cgggcggtcg
     1201 actgtatgaa cagcgtaacc gcgcctggga gttgattaac gatattcccg gcgtttcctg
     1261 cgtaaaaccg cgcggcgcgt tgtacatgtt ccccaggatc gacgctaaac gttttaatat
     1321 tcacgacgac cagaagatgg tgctggactt cctgctacag gaaaaggtgc tgctggtgca
     1381 aggtaccgcc tttaactggc cgtggccgga tcacttccgc attgtgacgc taccgcgtga
     1441 agatgacctg gagatggcca tcaaccgctt tgggcgtttc ctctcaggct accatcaata
     1501 atcttaaatt caggctactt cggtagcctg aattgcatct tcatcaccct ccccgcacaa
     1561 tgaagtctgc cgcagtgaaa acaaaaggta atctatgaag cagagccatt ttttcgccca
     1621 tctctcccgc atgaagttga ttaaccgctg gccgctgatg cgtaacgtgc gtacggaaaa
     1681 cgtctccgaa catagtctgc aggtggcgat ggtcgcccat gcgttggcgg cgataaaaaa
     1741 ccgtaaattt ggcggccagc tcaatgctga acgcatcgcg cttctggcga tgtatcatga
     1801 tgcctcggaa gtactgaccg gcgatctgcc aacgccggta aaatatttta attcccagat
     1861 agctcaggaa tataaagcga tcgaaaaaat cgcccagcaa aagctggttg atatggcgcc
     1921 ggatgaatta cacgatattt tcgcaccgct tattgatgag aatgcctgga gcaaagaaga
     1981 acaggcaatc gtaaagcagg ccgatgcgct ttgcgcctac ctgaaatgcc tggaggagct
     2041 ctcagcggga aataatgagt ttagactggc aaaaacgcgg ctggaaaaaa cgctggaatt
     2101 acgtcgcagc caggagatgg actattttat ggcggtgttc gtgccaagtt tccatctctc
     2161 tcttgacgag ataagccagg attcaccgct ttagttgccg gatggcggct aacgccttat
     2221 ccggcctacc gttcttcccg taggcctgat aagcgtagcg ccatcaggcc ttttccagcc
     2281 tggggttaaa acggaaacaa catcggaatc atcacaatac aaaccgccat cacaataagc
     2341 gtgaacggca cgccaagctt cacaaaatcg ctaaagctat agtttcccgg ccccagaacc
     2401 agagtattga ccggcgatga aaccggcgtc ataaaggcgg cggatgccgc catcgctact
     2461 gccatcgcaa acggataggg cgacaccccc atcgatttcg ccgccgccag cgcaatcggc
     2521 gccatcagca ccgccgttgc cgtgttagaa atgaacagtc ctatgacggc gcacagcacg
     2581 aacaggcatc ccagcatcat atacggccca tagccgccgc cgatatccat taacccttgc
     2641 acgaccagag agacgccgcc ggttttttgc aacgccagcg caaacggcat catacccaca
     2701 atcaagataa tactcggcca gtggatcgct ttatacgcgc tttcagcatc aatacagcga
     2761 aatttcccca tcagcaggca ggcgataatc gccgcgctcg gattgggaat ttcatcggtc
     2821 aacatcagcg ccaccatcag taccaggcag aaaatggcgt gcggcgcctg gctgtgcgcc
     2881 ggcgaggctt cgctgacctc gaccggcata ttcagcacca caaagtcgcg gcctttttgc
     2941 cccagcaggc tgattaactt ccagttcccc acgaccagaa tgatatcgcc catcaataac
     3001 ggttcatcgg ccagcgaccc ttccagcgcg acgccgtcgc gtttcaggcc gaccacattc
     3061 agcccgtaac gtgtacggaa ggcgatttca cgcaccgact tgcctatcag ttcagacttc
     3121 ggaataagcg aaatttccgc catgccaaca tccaacgcct gatcggaaaa atattctcca
     3181 cgcaatacca tcggttccag cagttgctcg gcgcagaact ctctgaggtc aacctccgcc
     3241 gccgacatat caatcagcag aacgtcgcga gcgcgaaact ccgatacgcc gttcacattg
     3301 acgataaccc gccgaaagcg ccgccagcgt tcaacgccga tgacattggc gccgtaacgt
     3361 tcgcgcagtt taaggtcgtc cagccgctgt cccaccatcg gcgaaccggg gcgaatcgcc
     3421 agacgacgcg cgcgccccgt cagacggtac tcgcggataa gatcgcggaa agtgcgacgc
     3481 ttaccggcct gttgtccggg cgcatcgcct tttagcatga agcgcatcac cagcatataa
     3541 acaatgccga gcgccaacac cactaccccc agcggcgtca cgctaaaaaa gttgaacccg
     3601 tgcaggcctt cacgcagcag ttcactgtta accaccaggt tcggcggcgt cgccaccagc
     3661 gtcatcattc cgctgataag cccggcaaaa ctcagcggca tcatcaggcg cgaaggcgag
     3721 gtctgcatat gcatagaaac gctaagaaca acggggataa aaatcgccac cacgccggtt
     3781 gaactcatga aagcaccaag tccggcgacg gtgatcatca gtaaaaccag catcttgatt
     3841 tcactgctgc ccgccatttt aaccagccag gtaccgacca ccgtcgcaac gccggtgcgc
     3901 acgaggccgt cgccaataat aaataaggcg gcgataagaa tgacattcgg atcgctaaag
     3961 ccggagaagg cttccgaaag ggtcaaggta ccgctaagga caaaagcaac aatgacgaat
     4021 aaagccaccg catccatacg tactttgccc gtcgcaaaca acacgacggc aatcgccagt
     4081 aaagagagaa cccaaatcaa ttcaccgttc acaacatatc cttgtcagat gagaagataa
     4141 cgtgattctg ccataaatat gccccgccag ggcggggcat atcatgatca ggtctttctt
     4201 aacaccacca catcgccgtt tggttgttta gcgaccgata attgcgtcag gctatccaac
     4261 gcaaaatcaa catccgccag acgcggcgtg tcggccggcg cattgaccgc aatgacgtgg
     4321 cagcccgcag ccagtccgga cagcacgcca gccggggcat cttctactac gacgcactcc
     4381 tgaggggcca ggccaagcag ttgtgcgccc agcaaatacg catccggctc cggtttgccg
     4441 cgtttgactc gttcggcggt gacaaacacc tctggcgctg gaaggcccgc gacctgatgg
     4501 cgcgcacgcg cgaccggcat tgaaccggag gtgacgatag cccacggaat gcccgcttta
     4561 ttcaggtgat tgagtaaatc gactgccccc ggcaacgcgg tgatccctgc ggtttcagtg
     4621 gcttctattt gctccaggcg cgtaaactca gcggcaattt ccgcctccga tttacccgcc
     4681 ataaaatgcc gcaacgaggt gatcgcctgt ttgccatgaa taaagcccag cacctcatca
     4741 tgagcaaggt taaaacgatc ggcccagcta caccacgcgc gttcgacggc aggtaatgag
     4801 tcaaccaacg ttccatccag atcaaacaga aaacctttac actgcacgtg agcctcctca
     4861 ggcattaatg atttgattga tttcattcgc gctcaggtgg tactgacgcg ggcaggcatg
     4921 ccagacattc aacatccgct ggtatttttc ccacatcggc gtctgggcat taaagccgtg
     4981 cgtcccggcg tcaaagtgag tgtagcgtcc ttctatattc accataaaac ggacatagcc
     5041 gaggtaacgc gcttccgtcg cggcgtcaaa ccccaggaag gtgacgcgac gttcgtcgat
     5101 ggcttgcgta tctttgaggt tggtccagga gacgtgcagc gcatggtaca tctccataat
     5161 atcgatgatg gtacgacagg tctcttccgt cagctcgcca aactcgcgat ccagctcgcg
     5221 catctgcagg ccgtagccgc gttcaataat tgtttgtaag cgacggtaac gctcggcgtt
     5281 ggtgggatcg agcatcgtca tcattttgta ctggttagac aaaatcagac gttgcgcgtt
     5341 ggtcatttcc attttgaact cctgtatcac gctatggcga tgaaaaaaag aaggcattgg
     5401 tatgccttct tttatatgcg taatccgggg tcaattacaa atcatccaag aaagttttat
     5461 ccagttgttt gaaggcgcgc ttaagcgtgt cagctaatgc ctggtaatcc ggctttcctt
     5521 ctaccggcgc cagcgcttgt ccagcctcct gcaatttacc gcgaacttcg taaaaccagt
     5581 taaggattga aggcggcaat ggcgtcaagg aacgtttccc taaccaccat aatccctgca
     5641 taggcaagct cagggcgaac agggcggtcg ccacggccgg acctaactga ccgcccagcg
     5701 ctatctgcca gcataatgta aagacggcga caggcggcat aaatcgtatg gcatagcgcg
     5761 tcatacgaat gacgcggttt tcgacgaaaa cgggcgccag ccgcttttcc atcggccacg
     5821 tcttcgcgta gtgctgcccc cggcgaaata agctaaaaaa atttacggag cgattatccg
     5881 gcgtcgacat ggcctacctc aatttcacat ataaaattta aaaaatttgt gcaaaacaac
     5941 aactgcgagg gacaacgttc aaaacatttt gtcttcgata cccactatca ggtatcctgt
     6001 gtcggcctgt caaaggccgg tagtttaaaa tcattgagtc gtcaatatta cacatagtat
     6061 gccattggct gaaaaatacg caaaatggca tagactcaaa ggtatttctt ccatcatgcc
     6121 caaaaaaact cctgcgcatg atgttaatca taaatgtcag ggctatcatg cgctacgctc
     6181 tatggctcac tgacgttttt ttagccacgt atcataaata ggtacttcca tgtcgagtaa
     6241 gttagtactg gttctgaact gcggtagttc ttcactgaaa tttgcaatta ttgatgcagt
     6301 taatggtgat gaataccttt ctggtttagc cgaatgtttc catctgccag aagcacgcat
     6361 caaatggaaa atggacggca gtaaacaaga agcggcttta ggtgcaggcg ccgctcacag
     6421 tgaagcgctg aactttatcg ttaacactat tctggcacaa aaaccagaac tgtctgcgca
     6481 gttaactgca attggtcacc gtatcgtaca cggcggcgag aagtatacca gctccgtagt
     6541 cattgatgag tccgtcattc agggcatcaa agattccgcc tctttcgcac cgctgcataa
     6601 cccggctcac ctgattggta tcgccgaagc gctgaaatct ttcccgcagc tgaaagataa
     6661 aaacgtcgcc gtgttcgaca ccgccttcca tcagaccatg ccggaagaat cttacctgta
     6721 tgccctgccg tacagcctgt ataaagaaca tggcgttcgt cgctatggcg cacacggcac
     6781 cagccacttc tatgtaactc aggaagcggc aaaaatgctg aacaagccgg tagaagaact
     6841 gaacattatc acctgccacc tgggcaacgg cggttctgtt tccgctatcc gtaacggtaa
     6901 atgcgtggat acctctatgg gtctgacccc gctggaaggc ctggtcatgg gtacccgttc
     6961 cggcgatatc gaccctgcga ttatcttcca cctgcacgac actctgggca tgagcgtgga
     7021 tcagatcaac aaaatgctga ccaaagagtc cggtctgctg ggtctgactg aagtgaccag
     7081 cgactgccgt tatgttgaag acaactacgc caccaaagaa gacgcaaaac gtgcgatgga
     7141 cgtttactgc caccgcctgg cgaaatacat cggttcttac accgctctga tggacggtcg
     7201 tctggatgca gtcgtgttca ccggcggtat cggtgaaaac gccgcgatgg ttcgcgagct
     7261 gtctctgggc aaactgggcg tactgggctt tgaagtcgac cacgaacgta acctggcggc
     7321 ccgcttcggc aaatctggtt tcatcaacaa agaaggtacc cgtccggcgg tggtgatccc
     7381 aaccaacgaa gaactggtta tcgcgcagga cgcgagccgt ctgactgcct gatttcacac
     7441 cgccagcctc gctggcggtg ctgttttgta acccgtcccc aaaagacggt aacgaaagag
     7501 gataaaccgt gtcccgtatt attatgctga tccctaccgg aaccagcgtc ggtctgacca
     7561 gcgtcagcct cggcgtcatc cgtgctatgg aacgcaaagg cgttcgtctg agcgtcttta
     7621 agcctatcgc ccagcctcgc gctggcggcg atgcgcctga ccagaccacc actatcgttc
     7681 gcgcgaactc taccctgccg gcggctgaac cgctgaagat gagccacgtt gaatctctgc
     7741 tctccagcaa ccagaaagac gtgctgatgg aagagatcat cgcaaactac catgcgaata
     7801 ccaaagacgc ggaagtggtg ctggttgaag gtctggttcc gacccgtaaa catcagttcg
     7861 ctcagtctct gaactatgaa atcgcgaaaa cgctgaatgc ggaaatcgtt tttgtcatgt
     7921 ctcagggtac cgacacgcca gaacagctga acgagcgtat cgaactgacg cgcagcagct
     7981 tcggcggcgc gaaaaacacc aacatcaccg gcgttatcat caacaaactg aatgcgccgg
     8041 ttgatgaaca aggccgtact cgcccggatc tgtcagagat ttttgacgac tcttccaaag
     8101 cgcaggtgat caaaatcgat cctgctaaac tgcaggaatc cagcccgctg ccggttctgg
     8161 gcgcggtgcc gtggagcttc gacctgattg cgacccgcgc tatcgatatg gcgcgtcacc
     8221 tgaacgccac catcattaac gaaggcgata tcaaaacccg ccgcgttaaa tccgttacgt
     8281 tctgcgcgcg cagtattccg catatgctgg agcatttccg cgcaggatcg ttgttagtga
     8341 cctcagctga ccgtccggac gtactggtcg cagcttgcct ggccgcgatg aacggcgtag
     8401 aaatcggcgc cctgctgctg accggcggct atgaaatgga cgcgcgcatt tctaaactgt
     8461 gcgaacgcgc attcgccacc ggtctgccgg tctttatggt gaacaccaac acctggcaga
     8521 cttcgctgag cctgcaaagc ttcaatctgg aagttccggt tgatgaccat gagcgcatcg
     8581 agaaagttca ggaatacgtc gcgaactacg ttaacgctga ctggatcgag tcgctgaccg
     8641 ccacttccga gcgtagccgt cgtctctctc cgccggcgtt ccgctaccaa ctgactgagc
     8701 tggcgcgtaa agccggtaaa cgcgtagtgc tgccggaagg cgacgaaccg cgtaccgtca
     8761 aagcggcggc aatctgcgct gaacgcggca tcgccacttg cgtactgctg ggcaacccgg
     8821 atgaaatcaa ccgcgtcgcg gcatctcagg gcgtagagct gggcgcaggt attgaaatcg
     8881 tcgatccgga agtggtgcgt gaaagctatg tcgctcgcct ggttgagctg cgtaagagca
     8941 aaggcatgac cgaaccggtt gcccgcgaac agctggaaga caacgtggtg ctcggcacgc
     9001 tgatgctgga gcaagacgaa gtcgacggcc tggtttccgg cgcggttcat accaccgcca
     9061 acaccatccg tccgccgctg cagcttatta aaacggcgcc gggtagctcc ctggtctctt
     9121 ctgtgttctt tatgctactg ccggaacagg tttacgttta cggcgactgc gcaatcaacc
     9181 cagacccgac tgcagagcag ctggcagaaa tcgcgattca gtctgcggat tccgccattg
     9241 ccttcggcat cgaaccgcgt gtggcaatgc tctcctactc caccggcacc tctggcgcgg
     9301 gcagcgacgt agagaaagta cgtgaagcga cgcgtctggc gcaggaaaaa cgtcctgacc
     9361 tgatgatcga cggtccgttg cagtacgacg ccgcggtcat ggctgacgta gcgaaatcca
     9421 aagcgccgaa ctcgccggtt gcgggtcgcg ctaccgtgtt cattttcccg gatctgaaca
     9481 ccggtaacac cacctacaaa gcggtacagc gttctgccga cctgatctcc atcgggccga
     9541 tgctgcaggg tatgcgcaag ccggtgaacg acctgtcccg tggcgcgctg gttgacgata
     9601 tcgtctacac catcgccctg acggcgatcc aggcttctca acagcagcag taacagtaaa
     9661 agctaatgcc ggatggcggc gtgaacgcct tgtccggcct acaggtgaga taccgttgta
     9721 ggccggataa gacgcgttag catcgccatc cggcattctg ctatttaccc tgcaaagcgg
     9781 aattttttgc ttaactgcgc tgcatcaatg aataactatt cccttcttct catacttggc
     9841 ctctttgctt tgcaacaggg atagtccgtc atgtctgtcg ttacagaatc aaaaacagcc
     9901 agaaaatggg caatgcccga tacgctggtc atcatctttt ttgtcgccat tttaaccagt
     9961 atcgccacct gggtcgtccc cgttgggatg tttgatagcc aggaagtgca gtatcaggtc
    10021 gatggtcaga caaaaacccg caaagtcgtc gacccgcact cttttcgcat tgtgaccaat
    10081 gaggccgggg aagcgcagta tcatcgcgta caatttttca ctaccggcga tgaaagacca
    10141 gggctgatga attttccgtt tgaagggtta acatccggat cgaaattcgg cactgccgtc
    10201 ggcatcatta tgtttatgtt ggtgattggc ggcgcattcg gcatcgtgat gcgtaccggc
    10261 accgtggata acggcattct ggcgcttatt cgccacacgc ggggcaacga agtcctgttt
    10321 attccggtgc tatttgtcct cttttcgtta gggggcgccg tatttggcat gggcgaagag
    10381 gcggtcgcct ttgcaattat catagccccg ctgatggtca ggctgggcta tgacagcatt
    10441 accaccgtcc tggtgaccta tatcgccacc caaattggct ttgccagttc gtggatgaac
    10501 ccgttttgcg tagtcgtcgc ccaggggatt gccggcgtgc cggtactttc cggctccggg
    10561 ctgcgtattg tggtctggat tgtcgccacg ctgattgggc tggtttttac gctggtctac
    10621 gcctcacgcg tgaaaaagaa tccgctgctt tcccgcgtcc acgaatccga tcgctatttc
    10681 cgcgaacagc aggatgaagt cgtccagcgc cctttcacct tcggcgactg gctggtactg
    10741 ctggttctga ccggcgtaat gatttgggtc gtctggggcg tgattgtcca cgcctggttt
    10801 attccggaga tcgccagcca gtttttcacc atgggcgtgg tgatcggcct catcggcgtt
    10861 atcttccgcc tcaacggtat gacggtcaac gtgatggcgt cctcattcac cgaaggggcg
    10921 aggatgatga tcgcgcccgc cttgctggtg ggttttgcca aaggcattct gctgctggtc
    10981 ggcaacggcg aagccgggga acccagcgtg ctcaatacgt tgcttaacag tatcgcgcat
    11041 ggcatcagcg ggcttaataa tgctatcgcc gcctggttta tgctgctctt ccaggcggta
    11101 tttaatttct ttgtcacgtc cggttcgggc caggcggcgt taaccatgcc attactggcg
    11161 ccgctcggcg atctggtcgg cgttaaccgt caggtgactg ttcttgcctt ccagtttggc
    11221 gatggcttca gccatattat ctatccgaca tcagcttcgc tgatggccac gctgggcgtg
    11281 tgccgggtcg attttcgcaa ctggcttaaa gtgggggcgt cgctgctggg actgctgttt
    11341 atcatgtcca gcgtggtcgt gattggcgcg cagatgatgg gatatcattg atccaaaatg
    11401 ccggatgagc atcagcgcca tccggcaata tctccatgat taaagcagtg atttcgcggc
    11461 ttctacaatc gctgcggcgg tgagtccgta ctcttgttgt aagaaatcct gcgttcctac
    11521 ctgcccataa cgctctttga cgccaacacg gcgcatcggc accgggcagt tttccaccag
    11581 cacttccgct accgctgacc ctagtccatt atggatactg tggttttcac acgtgacgat
    11641 acgccgcgtt ttttccgcgt agtttttcac caacatgcga tcgataggct ttaaggtgaa
    11701 catatcaatg accgcagcgc tcacgccttc ctgctccagt tggcgcgccg cctccagcgc
    11761 ctccgccacc ataatgccgt tggcgataag tgtaatatca tcgccctcgc gcagtacgtt
    11821 gcccttgcca atggtaaagg tagagcctgg cgcatagata ctcgtcgcct gcttacggat
    11881 ggtacgcagc cagtaaaaac cgtccaggtc cattagctgg cgtaaaatat tcgcgaacat
    11941 caccgcatcc gtcacctcca gtactacaga gtgcgccagc ccgcgaacaa tccccatatc
    12001 ttcaaaagac atatgagtgc cgccgttatg gcacgccgtc actccggcat cggaggcgat
    12061 cactttgacg ttgttacgct gataatccag cgccataaag agctgatcaa aacagcgacg
    12121 gctggcaaaa gcggtaaagg tatgcacaaa cggtttgcga ccggtcagcg ccagtcccgc
    12181 cgccgtgcca atcacattcg cctccataat accgcagtta atgacatgct gcgggtagtc
    12241 acgcgccacg ctgtccatcg ccatcgagct cattaaatca gcctcaagcg caataattgg
    12301 gcttccggcc tcaatctgcc cggcgacaaa accggcataa actttgcgca tttcgatatc
    12361 gtctttaagc cctgcgggcg caagcttaat catgcatgac ctccagttga tgaatggcct
    12421 cattgagcgt ctgcttcatg ccatccgtca ggcgtaagtg gtgagaattc gttaactgct
    12481 ccaggcatgg caccccctgc cctttaatgc tgtcaaggat cacaacccgt ggccgggcat
    12541 cagcgggcgg cacaggctga accaccgcca gtagtccggc gatatcatcg cctttgacgg
    12601 tgacgacatc gaaaccaaac gcgcggaatt tcccttccag atcgaatgga ttgataatct
    12661 cctccagctc gccgtcaagc tgttgtttgt tccagtcaat gaaaacggtc agattattca
    12721 ggcggtggtg ggcaataaac tgaaacgcct cccagcactg cccttcattc agctccccat
    12781 cgccgacaat gcaaaatacc cggttgggtc gccgcgccag tttatgcgac aacgccattc
    12841 cgcccgcaat agagatgcct tgtcccagtg agccggtcgt ggcgtccacg ccgtgcgttt
    12901 ttagccgatc cggatggctg ggaagacggg tgccgttctg gttaagcgta ttcagctctt
    12961 cgcgcgggaa atagccttta atcgccaggg tactgtacaa cgcggggccc gcatggcctt
    13021 tcgacagtac gaagtaatcg cgctccggcc agtccgggtc ggcagggtcg attttcatca
    13081 ccgcgccgta cagaaccgcc agagtctcca ctaccgacat gctgccgcca tagtgaccaa
    13141 agccaagatg gtttaaggat ttgagcgtgg cgacgcgaat gtcgcgcgcc agttgggtga
    13201 tttcggttac gttcattctt tcgctccgct attttcctgc acttcggcag tcgctttttt
    13261 gcttttggcc aacacgttgt acgccaccag tagcgcgaat agcgccacca ccagccccgt
    13321 gatagccatc ggcgacagat aacgcgccag gttgcccagc aaaataccga ttacgccaaa
    13381 gtcagcatcc gagaacgtgg tattggcgaa gccgatcgcg ccgagaaccg gcagtaacag
    13441 cactggcagg aaagtgatta atagaccatt agcaaatgcg ccgatcatcg ccccgcggcg
    13501 accgccggtg gcattgccaa agacgcctgc ggtcgcgccg gtaaagaagt gcggcacaac
    13561 gccaggcagg attaacacaa gcttcatctg tccaagcagg aacagcccca ccagcccgcc
    13621 gagaaaactg aacaggaagc caatcagtac cgcgttaggg gcatagggat acaccaccgg
    13681 gcagtccagc gccggacgcg cgtttggcac cagtttttct gaaaagccgg taaaggccgg
    13741 aacaatttcc gccagaatca gacggacgcc ttgcagaatg atgaatacgc cggcggcgaa
    13801 ggtgattgcc atgataatgg cgtacaccag atagttttgc ccgccgctaa acgtcgcttc
    13861 gacatactca cgccctgcgc tgactgccat gatcagatag ataatcatca tggtcagcga
    13921 aatcgagata gaactgtcgc gtaaaaaact gaggtttttc ggcaggttca tctcttccgt
    13981 ggagcgggag cctttaccac acaggctgcc aatccagccg gaaagcacat atcccagggt
    14041 accgaagtga ccaaacgcaa tgtcatcggt accggtaatc cgcctcatat aacgttgggc
    14101 caacgccggg aagaaggcca tcaccagccc caggattagc gatccggtga agaccagccc
    14161 tacgccctca aaccccgcca cggtcaggat tacgccaatc atacaggcca tgtaaaaggt
    14221 gtgatgtccg gtcaaaaaga tatatttaag acgcgtaaag cgcgccacga caatattggc
    14281 caccatacca aatgccataa ttaacgccgt ggacgcgcca tatttttcca gcgcgattga
    14341 gactatcgct tcattattag gaataatacc ctgaatatta aaagcgtgtt caaacatacc
    14401 ccctagcggg tttaatgaac ccaccagtac ggttgcgcca ccgccaagca caataaaacc
    14461 taaaatggtt ttaatcgtgc cttttaccac atcggaaaac gcttttttct gcgccaccag
    14521 accaatcagc gcaattaacc ctacaagcac cgatggcact tttaaaatat caacaacaaa
    14581 attcagcgtt tcaaggataa acatatccac ctcgccagca ataattattg tttagcgaac
    14641 catgcgcgca gctgcgtttc cagttcgttg atgtcgatga tgttattgat caccaccagt
    14701 tggctttccg gtacgctggc gctggccgcg atatctttgg ccattacaaa aagatcggca
    14761 gccccgggtg tggccgatga gagatcggag tgttccactt cagcgtcaat attgagtttc
    14821 tttaatactt ttttaatgt
//
LOCUS       DAJVBX010000109        14708 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.109, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000109 DAJVBX010000000
VERSION     DAJVBX010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 14708)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14708)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14708
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.109"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(14..1594)
                     /locus_tag="OPV72_002789"
     CDS             complement(14..1594)
                     /locus_tag="OPV72_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase"
                     /protein_id="HCR9915038.1"
                     /translation="MNSTLIDSLLARRRAVSPWAGLYFLQSLLINLALGYPFSLLYTA
                     AFTCLLLLLWRYLPRGQKALLGICSLVAACYFPFGQAYGAPNFNTLLALHSTNMEESS
                     EILTIFPWYSYLTGLFIFALGIIALRRRKEEVRPRWNSLDSLCLLISVAAFFVAPVQN
                     LAWGGVFKVIDTGYPVFRFAKDVIVNNNEVIEEQHRMAQLSGIKDSWTVTAVKPRYHI
                     YVVVIGESARRDAMGAFGGHWDNTPFASHVNGDFFMDYIAASGSTQKSLGLTLNRVVD
                     NKPQYQDNFVTLANRAGFQTWWFSNQGQIGEYDTAIASIAKRADEAHFLKNGDFEADK
                     NTRDDALLTMTAQVLATERTQPQLIVLHLMGSHPQACDRTHGKYATFVQSKETSCYLY
                     TMTQTDDLLRQLYTQLRHSGDSFSLVYFSDHRLAFKERGKAVQYLAHDDKFQQNFQVP
                     FMVLSSDSKAHRIIKARRSANDFLSFFSQWTGISAKEIKNRYRFISEQKAGPVYITNF
                     KLQKVDYNHLGSDIFSLK"
     gene            complement(1860..1988)
                     /gene="mntS"
                     /locus_tag="OPV72_002790"
     CDS             complement(1860..1988)
                     /gene="mntS"
                     /locus_tag="OPV72_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganase accumulation protein MntS"
                     /protein_id="HCR9915039.1"
                     /translation="MNEFKRCIRVFSHSPFKVRLMLLSMLCDMINGKPEQDNPSTK"
     gene            2174..2647
                     /gene="mntR"
                     /locus_tag="OPV72_002791"
     CDS             2174..2647
                     /gene="mntR"
                     /locus_tag="OPV72_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-binding transcriptional regulator
                     MntR"
                     /protein_id="HCR9915040.1"
                     /translation="MGRRAGTPTTKKVTQLVNVEEHVEGFRQVREAHRRELIDDYVEL
                     ISDLIIEVGEARQVDMAARLGVSQPTVAKMLKRLASLGFIQMIPWRGVFLTPEGEKLA
                     QESRERHQIVENFLLVLGVSPEIARRDAEGMEHHVSQETLDAFLAFTQQHGTSAE"
     gene            2644..3756
                     /locus_tag="OPV72_002792"
     CDS             2644..3756
                     /locus_tag="OPV72_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anion transporter"
                     /protein_id="HCR9915041.1"
                     /translation="MNLAFLRALRRDRFFQLLIIVGMALSLFVPFAPRAWPGAIDWHT
                     IITLSGLMLLTKGVELSGYFDVLGRKMTRRFHTERQLAMFLVLAAAALSTFLTNDVAL
                     FIVVPLTITLKKLCAIPVNRLIIFEALAVNAGSLLTPVGNPQNILLWGRSGLSFAEFS
                     GQMAPLAVMMMLTLLLLCWFCFPGRALQYHTGTRSPQWQPRLVWSCLALYVVFLTALE
                     LRQELWGLVLVAAGFIVLARRVIVSVDWTLLLVFMAMFIDVHLLTQLPALQGVFNQVG
                     ALSHLGLWLTAIGLSQVISNVPSTILLLNYVPASTLLAWAVNIGGFGLLPGSLANLIA
                     LRMANDRRIWWRFHFYSLPMLAWAALVGYGLLQLMP"
     gene            complement(3800..4720)
                     /gene="ldtB"
                     /locus_tag="OPV72_002793"
     CDS             complement(3800..4720)
                     /gene="ldtB"
                     /locus_tag="OPV72_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HCR9915042.1"
                     /translation="MNMKLTTLFAAAFAVVGFCKTASAVTYPLPTDGSRLIGQNQVIT
                     VPEGNTQPLEYFAAEYQMGLSNMLEANPGVDTFLPKGGTVLNIPQQLILPDTVHEGII
                     INSAEMRLYYYPKGTNTVIVLPIGIGQLGKDTPINWTTKVERKKAGPTWTPTAKMHAE
                     YRAAGEPLPAVVPAGPDNPMGLYALYIGRLYAIHGTNANFGIGLRVSHGCVRLRNDDI
                     KFLFENVPVGTRVQFIDEPVKATTEPDGSRYIEVHNPLSTTEAQFEGKEAVPITLNKS
                     ILAVTNEPDVDQTVVQQAVQDRSGMPVRLN"
     gene            4940..6535
                     /locus_tag="OPV72_002794"
     CDS             4940..6535
                     /locus_tag="OPV72_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATPase"
                     /protein_id="HCR9915043.1"
                     /translation="MLVSSNVTMQFGSKPLFENISVKFGGGNRYGLIGANGSGKSTFM
                     KILGGDLEPTLGNVSLDPNERIGKLRQDQFAFETFTVLDTVIMGHGELWEVKQERDRI
                     YALPEMSEEDGYKVADLEVKYGEMDGYSAEARAGELLLGVGIPLEQHYGLMSEVAPGW
                     KLRVLLAQALFSNPDILLLDEPTNNLDIDTIRWLEQVLNERDSTMIIISHDRHFLNMV
                     CTHMADLDYGDLRVYPGNYDEYMTAATQARERLLADNAKKKAQIAELQSFVSRFSANA
                     SKSRQATSRARQIDKIKLEEVKASSRQNPFIRFEQDKKLFRNALEVEALTKGFDNGPL
                     FKNVNLLLEVGEKLAVLGTNGVGKSTLLKTLVGDLDADHGTVKWSENARIGYYAQDHE
                     YEFENDLTVFEWMSQWKQEGDDEQAVRSILGRLLFSQDDIKKPAKVLSGGEKGRMLFG
                     KLMMQKPNILIMDEPTNHLDMESIESLNMALELYQGTLIFVSHDREFVSSLATRVIEI
                     TPERVVDFSGNYDDYLRSKGIES"
     gene            complement(6657..7922)
                     /locus_tag="OPV72_002795"
     CDS             complement(6657..7922)
                     /locus_tag="OPV72_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1479 domain-containing protein"
                     /protein_id="HCR9915044.1"
                     /translation="MTTPFTYETLPADPKAAIRQMKQALRAQIGDVQAVFDRLSATIA
                     ARVAEINDLKAQGQPVWPIIPFSELATGNISDATRAEVKRRGCAVIKGHFPREQALAW
                     DQSMLDYLDKNHFDEVYKGPGDNFFGTLSASRPEIYPVYWSQAQMQARQSEEMALAQS
                     FLNRLWQVERDGKRWFNPDISIIYPDRIRRRPPGTTSKGLGAHTDSGALERWLLPAYQ
                     QVFASVFNGNVEQYDPWNAAHRTEVEEYTVDNTTKCSVFRTFQGWTALSDMLPGQGLL
                     HVVPIPEAMAYILLRPLLDDVPEDELCGVAPGRVLPISEQWHPLLMAALTSIPPLEAG
                     DSVWWHCDVIHSVAPVENQQGWGNVMYIPAAPMCEKNLAYARKVKAALETGASPDDFP
                     REDYETTWEGRFTLRDLNIHGKRALGMDV"
     gene            8184..8993
                     /locus_tag="OPV72_002796"
     CDS             8184..8993
                     /locus_tag="OPV72_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HCR9915045.1"
                     /translation="MTVNVVVTDMDGTFLDDAKQYDRVRFMAQYQELKKRNIEFVVAS
                     GNQYYQLISFFPELKDEISFVAENGALVYEHGKQLFHGELTRHESRIVIGELLKDKQL
                     NFVACGLKSAYVSKNAPETFVALMAKHYHRLQPVNDYHDIDDILFKFSLNLPDEQIPL
                     VIDKLHVSLDGIMKPVTSGFGFIDLIIPGLHKANGISRLLKRWNRSPQNVVAIGDSGN
                     DAEMLKMAHYSFAMGNAADNIKALSRYHTDDNNHQGALNVIQAVLDGTDPF"
     gene            complement(9071..11503)
                     /locus_tag="OPV72_002797"
     CDS             complement(9071..11503)
                     /locus_tag="OPV72_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HCR9915046.1"
                     /translation="MTQLKLDTLSDRIKAHKTALVHIVKPPVCTERAQHYTEMYQQHL
                     DKPIPVRRALALAHHLAERTIWIKHDELIVGNQASEVRAAPIFPEYTVSWIEKEIDDL
                     ADRPGAGFSVSEENKRILHDVCPWWRGQTVQDRCYGMFTDEQKGLLATGIIKAEGNMT
                     SGDAHLAVNFPLLLEKGLDDLRDKVAERRSRINLTVLEDLHGEQFLKAIDIVLDAVSQ
                     HITRFAALARQMAGEESRESRRKELLTIAENCEVIAHQPPQTFWQALQLCYFIQLILQ
                     IESNGHSVSFGRMDQYLYPYYRRDVELNQTLDREHAIELLHSCWLKLLEVNKIRSGSH
                     SKASAGSPLYQNVTIGGQNLINGQPMDAVNPLSYAILESCGRLRSTQPNLSVRYHAGM
                     SNDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLGIEPQDAYDYAAIGCIETAVGGKW
                     GYRCTGMSFINFARVMLAALEGGRDATSGKVFLPQEKALSAGNFNNFDEVMAAWDTQI
                     RYYTRKSIEIEYVVDTMLEENVHDILCSALVDDCIERAKSIKQGGAKYDWVSGLQVGI
                     ANLGNSLAAVKKLVFEQGVIGQQQLAAALADDFDGLPHEQLRQRLINGAPKYGNDDDS
                     VDTLLARAYQTYIDELKQYHNPRYGRGPVGGNYYAGTSSISANVPFGAATMATPDGRK
                     AHTPLAEGASPASGTDHLGPTAVIGSVGKLPTGSILGGVLLNQKLNPTTLENESDKQK
                     LMVLLRTFFEVHKGWHIQYNIVSRETLLDAKKHPDQYRDLVVRVAGYSAFFTALSPDA
                     QDDIIARTEHML"
     gene            complement(11509..12408)
                     /locus_tag="OPV72_002798"
     CDS             complement(11509..12408)
                     /locus_tag="OPV72_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HCR9915047.1"
                     /translation="MIFNIQRYSTHDGPGIRTVVFLKGCSLGCRWCQNPESRARAQDL
                     LYDARLCLEGCDLCAQAAPDVIERALNGLLIHREKLTDAHFSILAHCCPTQALTVCGE
                     IKSVDEIMATVLRDKPFYDRSGGGLTLSGGEPFMQPELAAELFKASHDAGIHTAVETC
                     LHVPWKYIAPSLPYIDLFLADLKHVADGPFKQWTDGSASRVLENLRKLAAAGKKMVIR
                     VPLIQGFNADEETIKAITDFAADELHVGEIHFLPYHTLGINKYHLLSQPYHAPDKPLD
                     APALLDFAQKYACQKGLTATLRG"
     gene            complement(12686..13435)
                     /gene="moeB"
                     /locus_tag="OPV72_002799"
     CDS             complement(12686..13435)
                     /gene="moeB"
                     /locus_tag="OPV72_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-synthase adenylyltransferase MoeB"
                     /protein_id="HCR9915048.1"
                     /translation="MAELSDQEMLRYNRQIILRGFDFEGQEALKDARVLVVGLGGLGC
                     AATQYLAGAGVGQLTLLDFDTVSVSNLQRQTLHSDATVGQPKVESARDALARINPHIT
                     ITPVNARLDDDAMTSLIAGHSLVLDCTDNVSVRNQLNAGCYIAKVPLISGAAIRMEGQ
                     VTVFTYRENEPCYRCLSRLFGENALTCVEAGVMAPLIGVIGSLQAMEAIKLLAHYGQP
                     ASGKIVMYDAMTCQFREMKLMRNPGCEVCGQ"
     gene            complement(13435..14670)
                     /gene="moeA"
                     /locus_tag="OPV72_002800"
     CDS             complement(13435..14670)
                     /gene="moeA"
                     /locus_tag="OPV72_002800"
                     /EC_number="2.10.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HCR9915049.1"
                     /translation="MEFSAGLMPLETALTQMLSRITPLTAVETLPLMNCFGRILATDI
                     VSPLDVPGFDNSAMDGYAVRVADLSADKPLPVAGKAFAGQPYQGEWPAGTCIRIMTGA
                     PVPAGCEAVVMQEQTEQTDDGVRFTTDVRCGQNIRRRGEDIRQDAVVFPAGTRLTTAE
                     LPVLASLGIADAQVVRKVRVALFSTGDELQLPGQLLEAGQIYDTNRLTIHLMLQQLGC
                     EVINLGIIPDDPGKLRAAFVDADSQADVVISSGGVSVGEADYTKTILEELGEIAFWKL
                     AIKPGKPFAFGKLSNSWFCGLPGNPVSAALTFYQLVQPLLAKLGGNTASAVPPRQRVR
                     TTSRLKKTPGRLDFQRGILQRSANGELEVTTTGHQGSHIFSSFNLGNCFIVLERERGN
                     VEPGEWVEVEPFNALFGGL"
BASE COUNT         3323 a         3812 c         4111 g         3462 t
ORIGIN      
        1 cctgaaacgt gcattatttt agtgaaaaaa tatcgctgcc cagatggtta tagtccactt
       61 tctgtaattt gaaattggtg atataaacgg gcccggcttt ctgttccgaa ataaatcgat
      121 agcgattttt gatctcttta gcgctaattc ctgtccattg cgagaaaaaa ctcaggaaat
      181 cgttcgcgga acggcgagct ttaatgatcc gatgcgcttt actgtcgctg gatagcacca
      241 taaacggcac ctggaagttt tgctggaatt tgtcgtcatg cgccaggtac tgtaccgctt
      301 tgccgcgctc tttaaacgcc agcctgtgat cggagaaata gacgagcgaa aaactgtcgc
      361 cgctatgacg aagctgagta tagagctgac ggagcaaatc gtcggtttgc gtcatggtgt
      421 ataaataaca agacgtctct ttcgactgga caaacgtcgc gtattttcca tgagtacggt
      481 cgcaggcctg gggatgcgat cccattaaat gcaacacaat caactgcggt tgcgtgcgtt
      541 ctgtcgccaa tacctgcgcc gtcatggtta acagcgcgtc gtcgcgagta tttttatccg
      601 cttcaaaatc gccgtttttc aggaaatgcg cttcatcggc gcgtttggcg atactggcga
      661 tggccgtgtc gtattcgccg atttgcccct gattggaaaa ccaccatgtc tgaaaaccgg
      721 cgcggttagc cagcgtgacg aagttatcct gatactgcgg tttgttatcc accacgcgat
      781 tgagcgttaa accgagcgat ttttgcgttg agccgctggc ggcgatgtaa tccataaaga
      841 agtcgccatt cacatggctg gcgaaggggg tattatccca gtggccgccg aaagcgccca
      901 tggcatcccg tcgcgcgctt tcaccaatca ccacgacata gatgtgatat ctgggtttca
      961 ccgcagtaac cgtccagcta tcttttatgc cggatagctg cgccatacgg tgctgctctt
     1021 caatgacttc gttgttattg acgataacgt ctttggcgaa gcgaaaaacc ggatagccgg
     1081 tatcaataac cttaaaaacg ccgccccagg ccagattttg taccggcgcg acgaaaaatg
     1141 ccgcgacgct aatcagcagg cacaggctgt cgaggctatt ccagcgcggc ctgacctctt
     1201 cttttcggcg gcgaagcgca ataataccca gcgcaaaaat aaaaagtccg gtcaggtagc
     1261 tataccacgg gaagatggtc aggatttcgc tcgactcttc catattggtg gagtgcagcg
     1321 ccagcagcgt attaaagttc ggcgcgccgt aagcctggcc aaagggaaaa tagcaagcgg
     1381 ctaccagcga acagatgccg agcagcgctt tttgtccgcg aggcaggtag cgccagagca
     1441 gcagcaacag gcaggtaaac gccgcggtat aaagcaggct aaaggggtag ccgagcgcga
     1501 ggttaatcag cagcgactgt aaaaagtaga ggcccgccca tgggcttaca gcccgacgac
     1561 gggccagaag tgaatcgata agggttgaat tcatatgcca ctattgcaaa aacgccatgt
     1621 gctaaccctg gcgcgaaggg tcattacctg cctgattatg cgtaaaaaag gtattgggtt
     1681 cgcaacggcg agtcgcaaaa tattcaaggc tgccagaaga tagagcgtgc gggtaagaag
     1741 gccaaccgcc ggaaagaaaa tgttttgcga agagaatagc aaaaccacaa aaaaaacagg
     1801 ggaaatgggc gccatttccg ttgaggatgc aaaataaagc ggcgtaccgc accgccgcgt
     1861 tatttcgtgg aagggttatc ctgttccggt ttgccgttga tcatatcgca caacatagag
     1921 agcagcatta accggacttt aaagggagag tgactgaaca cgcgtataca cctcttaaat
     1981 tcgttcatat aaacctcctg atgtttctat cccatcgatc cgtgagggat gtctgcatta
     2041 catacagata tagcacaggc tatgttttat agctattgct aaaacgttaa ttttttgtgc
     2101 ccggacaact ctggtttaca atgagcgctc tgtcagctga cgcgttaacg cgtcacagaa
     2161 acgaggaagc aaaatgggtc gtcgcgcagg tacgccaaca acaaaaaaag tgacgcaatt
     2221 ggtgaacgta gaagaacacg ttgaaggatt tcgtcaggtc agagaggcgc atcggcgtga
     2281 gttgatagac gactacgttg agctgatttc cgatttaatt attgaggtag gggaagcgcg
     2341 tcaggtggat atggcggcgc ggctcggcgt ctcccagccg actgtggcca aaatgcttaa
     2401 gcgcctggca tcgttaggat ttattcaaat gatcccctgg cgcggcgttt ttctgacgcc
     2461 ggaaggggag aagctggcgc aggaaagccg cgagcggcat caaattgtcg aaaatttttt
     2521 actggtatta ggcgtaagcc cggaaatcgc gcgtcgtgat gcggaaggga tggaacacca
     2581 tgtcagccaa gagacattag atgccttttt ggccttcacg caacagcatg gaacatctgc
     2641 agaatgaatc tggccttttt acgggcgctg cggcgtgacc gtttttttca gttgttgatc
     2701 attgtgggga tggcgttaag cctgtttgtt ccttttgcgc cccgcgcctg gcctggcgcg
     2761 attgactggc acaccattat taccctcagt gggttaatgt tgctcactaa aggcgttgag
     2821 ctgagcggct attttgatgt gctgggacgc aagatgacgc gccgatttca taccgagcgg
     2881 caactggcga tgttcctggt gctggctgcg gcggcgctgt cgacctttct gacaaacgat
     2941 gtcgcgctgt ttatcgttgt gccgctgacg ataacgttaa aaaaactgtg cgcgattccg
     3001 gtcaaccgat tgattatttt tgaagcgtta gcggtgaacg ccggttcgct gctgacgcct
     3061 gtcggtaatc cgcaaaatat tctgttgtgg ggacgctccg gcttaagctt tgctgaattt
     3121 agcgggcaaa tggcgccgct tgccgtcatg atgatgctga cgttactgct cctgtgctgg
     3181 ttttgttttc cgggtagggc gttacagtat cataccggta cgcgttcgcc gcagtggcag
     3241 ccccgtctgg tgtggagttg cctggcatta tatgtcgttt ttcttaccgc gctggagctc
     3301 aggcaagagt tatggggact ggtgttggtg gcggctgggt ttattgtgct ggcgcgcagg
     3361 gtgatagtca gcgtggactg gacgctgctg ctggtattta tggcgatgtt tattgatgtc
     3421 catctgctaa cgcaattgcc ggcgttgcag ggcgttttca accaagttgg cgcactgtct
     3481 cacctgggac tttggctaac cgctatcggc ctgtcgcagg ttatcagtaa tgtgcccagt
     3541 accattctcc tgctgaacta tgtaccggcc tcgacgttgc tggcgtgggc ggtgaatatc
     3601 ggcgggtttg gtctgctgcc ggggtcgctg gcaaatctta ttgctttacg gatggcgaac
     3661 gatcgccgaa tctggtggcg atttcatttc tattcgctgc cgatgctggc atgggcggcg
     3721 ctggtgggat atggattatt gcaactgatg ccgtaagaga agcccgatag tgtctatcgg
     3781 gcttcgcagg cagagtctgt cagttcagac gaaccggcat cccggaacga tcctgaactg
     3841 cctgttgtac gacggtctga tcaacgtcag gctcgttggt gacggccagg atactcttat
     3901 taagcgtgat cggcaccgct tccttacctt caaactgcgc ttccgtcgtt gacagcgggt
     3961 tatgcacctc aatgtaacgg ctaccgtccg gctcggtggt ggcttttacc ggttcatcga
     4021 taaactgcac gcgggtaccg accggcacat tttcaaacag gaatttgata tcgtcgttgc
     4081 gcagacgtac gcagccgtgg ctcacgcgaa gcccgatgcc gaagttggcg ttggtgccgt
     4141 gaatagcata caggcgaccg atgtacagcg cgtacaggcc catcgggtta tccgggcccg
     4201 caggcacgac ggcaggcagc ggctcgccgg cggcgcgata ttcagcgtgc atttttgccg
     4261 taggcgtcca ggtcggaccg gcttttttac gttcaacttt ggtcgtccag ttgataggcg
     4321 tgtctttacc taactgaccg atcccaatcg gcaggacgat aacggtgttt gtgcctttcg
     4381 ggtagtaata gaggcgcatt tccgcgctat tgatgataat gccttcgtgt acggtatccg
     4441 gcaggatcag ctgctgcgga atattcagca cggtaccgcc cttcggcagg aaggtatcca
     4501 cgccagggtt ggcttccagc atgttggaga gccccatctg atactccgcg gcaaaatact
     4561 ccagcggctg ggtattgccc tccggaacgg tgatgacctg attttgccca attaaacggc
     4621 taccatcggt aggcagcggg taagtgactg ctgaggctgt tttacaaaaa ccaactacag
     4681 cgaaagccgc cgcgaaaagc gttgttaatt tcatattcat gttatgcgag attctgtgcc
     4741 aagcaggcta gtaggttgag aattctgtca tgttgggagc gcattatagg tgcattccag
     4801 taaacaggga attcagatgt gtacgaaatc acgttttttt ccccttacgg ttcagtgtag
     4861 ccctttgtat agggcgcgat cttatttcag acttgtggca taataagcgg tttgtcacat
     4921 cttttttcag gataagcctg tgttagtttc cagcaacgtt accatgcagt tcggcagtaa
     4981 gccgctgttc gaaaatattt ccgtcaaatt tggcggcggc aaccgttacg gcctgatcgg
     5041 cgccaacggt agcggaaagt ccacttttat gaaaatcctc ggcggcgacc tggagccgac
     5101 gctgggcaat gtttccctcg atccgaatga gcgcatcggt aagctgcgtc aggaccagtt
     5161 cgcttttgaa acattcaccg tacttgatac tgtcattatg gggcatggcg aactgtggga
     5221 agtcaagcag gagcgcgacc gtatctatgc cttgccggaa atgagcgaag aagacggcta
     5281 taaagtcgcc gatctggaag taaaatacgg cgagatggac ggttattccg ctgaggcgcg
     5341 tgcgggcgaa ctgctgttgg gggtgggcat cccgctggag cagcattacg gtctgatgag
     5401 tgaagtcgcg ccaggctgga aattgcgtgt gctactggcg caggcgttat tctctaatcc
     5461 ggacatcctg ttgctcgacg aaccgaccaa caacctggat attgatacta tccgttggct
     5521 ggagcaggtg ctgaacgagc gcgatagcac gatgatcatc atttcgcacg accgtcactt
     5581 cctgaacatg gtttgtacgc atatggcgga tctggattac ggtgacttgc gcgtctatcc
     5641 gggtaactat gatgagtata tgacggcggc gacccaggcg cgtgaacgtc tgttggccga
     5701 taatgcgaag aaaaaagcgc aaattgccga gctgcaatct tttgttagcc gttttagcgc
     5761 caatgcctct aaatcgcgtc aggcaacgtc gcgcgcgcgg cagattgata aaatcaagct
     5821 ggaagaggtg aaagcctcca gccgtcagaa cccgttcatc cgttttgagc aggataaaaa
     5881 actgttccgt aacgctctgg aagtggaggc gctgacgaaa ggttttgata acggtccgct
     5941 gtttaaaaat gtcaatttgc tgctcgaagt cggcgagaag ctggcggtac tcggcaccaa
     6001 tggcgtgggt aaatctacgc tgctgaagac gctggttggc gatctggacg ccgatcacgg
     6061 caccgttaaa tggtcggaaa acgcgcgtat tggttactac gcgcaggacc acgaatatga
     6121 attcgaaaat gacctgacgg tgtttgaatg gatgagtcag tggaaacagg aaggcgacga
     6181 cgagcaggca gtgcgcagta ttctgggccg cctgttattt agccaggatg atatcaaaaa
     6241 gcctgcgaaa gtcctctccg gtggcgagaa gggccgtatg ctgttcggca aactgatgat
     6301 gcaaaagccg aatatcctga tcatggacga accgactaac cacctggata tggagtcgat
     6361 cgaatcgctg aatatggcgc tggagctgta tcagggcacg ctgatctttg tttcgcacga
     6421 ccgtgagttc gtcagctcgc tggcaacccg cgtcattgaa attacgccgg agcgcgtggt
     6481 ggacttcagc ggtaactacg acgattattt gcgtagtaaa gggattgaaa gctaaacact
     6541 gacgcccggt ggcgctgtgc ttaccgggcc tacgtatcct ggcgcgtaga tctggtaaga
     6601 cgggtgcgcc cagacaaagg gcacaccgca gttgagcggg cagggctgta cgaccgtcaa
     6661 acgtccatac ctaatgcccg cttgccgtga atattcagat cgcgcagcgt gaaacgccct
     6721 tcccaggtgg tttcatagtc ctcgcgcggg aaatcgtccg gtgatgcgcc tgtctccagc
     6781 gccgctttca ccttacgcgc ataggccaga tttttctcac acattggcgc ggcaggaatg
     6841 tacatcacat tgccccagcc ctgctgattt tcgacggggg cgacggagtg gatgacatcg
     6901 caatgccacc acacggaatc cccggcttcc agcggcggaa tgctggttaa cgccgccatc
     6961 agtaaaggat gccactgttc agaaatcggc agcacccggc ccggcgcgac gccgcataat
     7021 tcatcttccg ggacatcatc cagcagcggg cgcagcagaa tatacgccat cgcctccgga
     7081 atagggacga catgaagcaa cccctgaccg ggcagcatat cggagagcgc ggtccagccc
     7141 tggaaggtgc gaaataccga gcattttgtg gtgttatcca ccgtgtactc ttcaacttcg
     7201 gtacggtgcg ccgcattcca cggatcgtac tgctcgacgt tgccgttaaa cacgctggcg
     7261 aatacctgct gataggctgg tagcagccag cgctccagcg cgccggagtc ggtatgcgct
     7321 cccagtcctt tggatgtggt gcccggcggg cggcgacgga tgcgatccgg gtaaatgatg
     7381 ctgatatccg gattaaacca tcgcttgccg tcgcgctcta cctgccacag acggttgagg
     7441 aacgactgcg ccagcgccat ctcttcactt tggcgggcct gcatttgcgc ctgcgaccag
     7501 tagacaggat agatttcagg ccgggaggcg ctcagcgtac cgaaaaaatt atcccccggt
     7561 cctttataca cctcgtcaaa atggttcttg tccagatagt cgagcatcga ctggtcccat
     7621 gccagcgcct gttcgcgtgg aaaatgacct ttaatcaccg cgcacccgcg gcgcttaacc
     7681 tcggcgcggg tagcatcgct aatgttgccc gtcgccagtt cgctaaaagg gataattggc
     7741 cataccggct gtccctgcgc cttcagatcg ttaatttccg ccacccgggc tgctatggtg
     7801 gcgctcaaac ggtcgaacac cgcctgtacg tcgccgattt gcgcgcgtag cgcctgcttc
     7861 atctgacgaa tggccgcttt tgggtcggcg ggcagcgttt cgtaggtaaa aggagtcgtc
     7921 atatcaacct caccatcttt cgttcgaaag taaaattagt tacatgtgat actttaagtt
     7981 aaaataaggt taatgcaagt ttaaaatatt gcaggggcgc acaaggaggg aagcgagagg
     8041 aaaacgtaag gtggccagga cgccttaatg tcttatgcgg ctattccttt cgttcagcca
     8101 cttttcattc gaaataaatt tgtggttctg ctcacattgt tattaaaatg tttctggtcg
     8161 cagttacagc caggagctta agtatgaccg ttaacgttgt cgttaccgat atggacggca
     8221 cttttctcga cgatgccaag cagtacgatc gtgtacgctt catggcgcaa taccaggaac
     8281 tgaaaaaacg taatatcgaa tttgtggtcg ccagcggtaa tcagtactat cagttgatct
     8341 ccttcttccc cgagctgaaa gacgaaattt ccttcgtcgc agaaaatggc gcgctggtgt
     8401 atgaacatgg caagcagttg tttcacggag agctaacccg gcatgaatcg cgtattgtga
     8461 ttggcgaact gctgaaggat aagcagctta acttcgtcgc ctgcggtctg aaaagcgctt
     8521 atgtcagcaa aaacgctccc gagactttcg tggcgctgat ggccaaacat tatcaccgcc
     8581 tgcagccggt aaacgattat cacgacattg acgatatcct gtttaagttc tccctgaatt
     8641 tgcccgatga acaaattccg ctggttatcg acaaactgca cgtatctctg gatggcatca
     8701 tgaagcctgt caccagcggc ttcggtttta tcgacctgat tatcccggga ctgcataaag
     8761 cgaatggcat cagtcgtctg ttaaagcgct ggaacaggtc gccacagaat gtcgtcgcca
     8821 ttggcgacag cggtaatgat gcggaaatgt tgaaaatggc gcattactct tttgccatgg
     8881 gcaatgccgc agacaatatc aaagcgcttt cacgttatca cactgatgat aataaccatc
     8941 aaggcgcgct caacgtcatt caggccgtgc ttgacggcac cgatcccttc tgattaacag
     9001 gcctgcgtag gcctgttaag cgtagcgcca tcaggcagtt cggacatatt gccgatggcg
     9061 cctgggcaaa ttacagcata tgttcggtac gggcgatgat atcgtcctgc gcgtccggcg
     9121 acagcgcggt gaagaaggcg gagtagcctg ccacacgcac gaccagatcg cggtactggt
     9181 ccggatgttt tttcgcatcc agcagcgttt cgcgtgacac gatgttgtac tgaatatgcc
     9241 agcctttatg cacctcaaag aacgtccgta gcagaaccat cagtttctgt ttgtcggatt
     9301 cgttttccag cgtcgttggg ttcagtttct gattgagcag cacgccgccg agaatggaac
     9361 cggtaggtaa tttgcctacg gaaccaatca ccgccgtcgg gccgagatga tccgtacccg
     9421 atgcagggct tgcgccttcc gccagcggtg tatgcgcttt gcgaccatcc ggggtagcca
     9481 tagttgcggc gccaaatggc acgtttgctg agatagagga cgtaccggcg taatagttgc
     9541 cgcccacagg gccacgacca tagcgcgggt tatggtattg cttcagctca tcaatatagg
     9601 tctgataagc gcgcgccagc agggtatcga cactgtcatc gtcgttaccg tatttcggcg
     9661 cgccgttaat cagacgctgg cgcagctgct catggggcag cccgtcaaag tcatcggcca
     9721 gcgcggcggc aagctgctgt tgaccgataa cgccctgttc gaagaccagt tttttcacgg
     9781 cggcgaggct gttgcccagg ttggcgatac cgacctgcag accggatacc cagtcatatt
     9841 ttgcgccgcc ttgcttgata ctcttcgcgc gttcaataca gtcgtctacc agcgctgagc
     9901 acagaatatc gtggacgttc tcttccagca tggtgtcgac cacatactca atttcgatcg
     9961 atttgcgcgt gtagtagcga atttgggtat cccaggcggc catcacttcg tcaaaattgt
    10021 taaagttgcc tgcggagagc gccttttcct gcggcagaaa taccttgccg ctggtggcgt
    10081 cgcgaccgcc ttccagcgcc gccagcatga cgcgggcgaa gttaataaag ctcatgccgg
    10141 tgcagcgata accccatttc ccgccgacgg cggtttcgat acagccgatc gccgcgtaat
    10201 cgtaagcgtc ctgtggttcg atccccaact tgataaattc cgggatgacg atttcatcat
    10261 tgttaaacgc cggcatccca aagccgcagc ggatgacctg gacgcaggcg tcaaggaaat
    10321 cgttactcat tccggcgtga taacgcacac tgaggttggg ctgggtagaa cgcaaacgtc
    10381 cgcaggactc cagaatagcg taagacagcg gattcactgc gtccattggc tgaccgttga
    10441 taagattctg accgccaatg gtgacgtttt gatacagcgg gctgcccgcg gaagctttag
    10501 agtgcgaacc ggagcggatc ttgtttactt ccagcagttt cagccagcag ctgtgcagca
    10561 gttcaatggc gtgctcacga tccagcgtct ggtttagttc gacatcgcga cgataatagg
    10621 ggtaaagata ctggtccata cgaccaaatg acaccgagtg accgttagac tcaatttgta
    10681 gaatcagttg gatgaagtag cacaattgca gtgcttgcca gaaggtctgc ggcggttggt
    10741 gggcgatcac ctcgcagttt tccgcgatgg taagtagctc tttacgacgg ctttcacggg
    10801 actcttcgcc cgccatctgg cgcgccagcg cggcaaagcg cgtgatatgc tggcttaccg
    10861 cgtccagcac aatatcaatc gccttcagga actgctcgcc atgcagatct tccagcacgg
    10921 tcaggttgat gcgtgagcgg cgctcggcga ctttatcgcg caggtcatca agcccttttt
    10981 ccagcagcag cgggaagttc accgccaggt gcgcgtcacc ggaagtcata ttaccttcgg
    11041 ctttgataat gccagtcgcc agaagccctt tttgttcatc ggtaaacatg ccgtagcagc
    11101 gatcctggac ggtttgaccg cgccaccacg gacagacgtc gtgcagaata cgtttgtttt
    11161 cttcacttac ggaaaaacct gcgccgggcc ggtctgccag gtcgtcgatc tctttttcaa
    11221 tccacgagac ggtatattcc gggaaaatcg gcgcggcgcg gacttcactt gcctggttgc
    11281 cgacgatcag ttcatcgtgt tttatccaga tagtgcgttc cgccaggtga tgggccagcg
    11341 ccagcgcgcg gcgtaccgga atcggtttat ccagatgttg ctgatacatt tcggtataat
    11401 gctgcgcgcg ctcggtacag accggcggtt tcacgatatg taccagcgcg gttttgtgcg
    11461 ccttaatgcg gtcactgagc gtgtccagtt tcagttgggt catgataatt atcctcgtag
    11521 ggtcgcggtt aaaccttttt ggcaggcgta cttctgggca aaatcaagta acgccggtgc
    11581 atccagtggt ttatccgggg catgataggg ctgactgagt aagtggtatt tattgatgcc
    11641 cagcgtgtgg tagggcagaa aatgaatttc cccgacgtgc agttcgtcgg cggcaaagtc
    11701 ggtaatggct ttaatggtct cctcatcggc attaaatccc tgaatcagcg ggacgcgaat
    11761 caccattttt ttgcccgcgg cggcgagttt cctgagattt tccagcaccc gcgaggcgct
    11821 gccatcggtc cactgcttaa acggcccgtc ggcgacgtgt ttcaaatcag ccagaaacag
    11881 atcgatataa ggcagtgagg gcgcaatgta tttccatggg acatgcagac aggtctcaac
    11941 cgctgtatga ataccggcgt catggctggc tttaaacagc tctgccgcca gctccggctg
    12001 cataaacggt tcgccgccgg aaagcgtaag accgccgccg ctgcgatcgt aaaaaggttt
    12061 atcgcgcagt accgtcgcca tgatctcatc cacgcttttt atttcgccgc acacggttaa
    12121 cgcctgtgtg gggcagcaat gcgccaggat ggaaaaatgg gcgtcggtca gtttctcgcg
    12181 atggatgagc aggccgttta gcgcgcgctc aatgacgtcc ggcgcggctt gcgcgcacag
    12241 gtcgcatcct tcgagacaca gccgcgcgtc gtataacaga tcctgagcgc gggcgcggct
    12301 ttccgggttc tggcaccagc gacagcccaa cgaacagcct ttgagaaata ctacggtacg
    12361 gataccgggg ccatcgtggg tggaatagcg ctgaatattg aagatcataa acggcctctc
    12421 ttatttcatg taaagattaa attactttcg aatgaaagtt atcttgatgt gcgtcaacga
    12481 atggagaggt tctgacaaag aggcgttaaa tgaggtacaa catcacgggt tgaggctgtg
    12541 atatggcgtt taagatgatg ccgcgctgct tgagccgatc gtcagtcgga gcttgggtaa
    12601 gctggctttg cgtctgatgg cagtaattat ctgttgatac agcacggcca tagaccgtgc
    12661 tttggtatgt ttatccgtaa agtgactact gcccgcagac ctcacagccg gggttgcgca
    12721 tcaacttcat ttcgcggaac tgacaggtca tcgcatcgta catgacgatt tttccgctgg
    12781 caggctgacc gtaatgcgcc agtagcttaa tggcctccat tgcctgtagc gaaccgatca
    12841 cgccaatcag cggcgccatc actccagctt ctacgcaggt cagagcgttt tcgccaaaca
    12901 gacggctcag gcagcggtaa cagggttcgt tttcccgata cgtaaagacg gtaacttgtc
    12961 cttccatacg aatggccgcg ccggagatta gcggcacttt cgcgatatag cacccggcgt
    13021 taagttgatt acgtacgcta acgttatcgg tacagtccag caccagcgaa tgcccggcaa
    13081 tcaggctggt catagcgtcg tcgtccagcc gcgcgttaac gggcgtaatg gtaatatgcg
    13141 ggttgattcg cgccagcgcg tcgcgggcgg actctacctt tggctgcccg accgtggcgt
    13201 cgctgtgcaa ggtttgacgc tggagattgg aaacggaaac ggtatcaaaa tcgagtagcg
    13261 tcagttgccc gacgccagcg ccggccagat actgcgttgc cgcgcagccg agtccgccca
    13321 gcccgaccac taatacccgc gcatctttta acgcttcctg cccttcaaaa tcgaagccgc
    13381 gcagaataat ttgtcggtta tagcgcagca tctcctggtc gctaagttcc gccattacag
    13441 gcctccgaac agagcattaa acggctcgac ttccacccat tctcccggct caacattgcc
    13501 gcgttcacgc tccagcacaa taaagcagtt gcccagatta aacgagctga aaatatgtga
    13561 gccctggtgt ccggtggtcg tgacctccag ttcgccgttg gcgctacgtt gcaggatgcc
    13621 gcgctggaaa tcgagacgcc ccggcgtttt cttcaggcga gatgttgtgc gtacacgctg
    13681 gcgcggcggt acagcgcttg ccgtattgcc gccaagcttc gccagtaagg gctgaaccag
    13741 ttgataaaac gtgagcgccg cagagactgg attccccggc aggccacaga accagctatt
    13801 actgagcttg ccgaaggcaa acggtttgcc tggcttgata gccagcttcc agaaggcgat
    13861 ttcgcccagc tcctcaagga tggttttggt atagtccgct tcaccaaccg agacgccgcc
    13921 ggagcttatc actacatcgg cctggctgtc ggcgtcgaca aacgcggcgc gaagcttacc
    13981 gggatcgtca ggaataatgc ctaaattgat cacttcgcag ccaagctgtt gcagcatcaa
    14041 atgtatagtt agacggttag tgtcataaat ttgtcccgcc tccagcagct ggcccggaag
    14101 ctggagctcg tcgccggtcg agaacagcgc tacgcgcact ttacgtacta cctgcgcatc
    14161 ggcaattccc agcgacgcca gcaccggcag ttcggcagta gtcaggcgcg taccggctgg
    14221 aaagaccacc gcatcctggc gaatatcctc gccgcggcgg cggatgtttt gtccgcaacg
    14281 aacatcggtg gtaaaacgca cgccgtcatc agtttgttcc gtctgctctt gcatgacgac
    14341 cgcctcgcaa cctgccggca ccggggcgcc ggtcataatg cgaatacagg ttcccgcagg
    14401 ccattctcct tggtaaggct gaccggcaaa tgctttgccg gcgacgggca gcggcttatc
    14461 ggcggacaaa tccgccacac gtaccgcata accatccata gctgaattat caaagccggg
    14521 gacatcaagg ggagatacga tatcggtcgc caggatgcgg ccaaagcagt tcatcagcgg
    14581 caacgtttct acggcggtga gcggggtaat acgtgaaagc atctgggtca gcgccgtttc
    14641 aagcggcatc aatccggcgg aaaattccat gaacatactc ctgcgaggca aaatcgaatc
    14701 cggctatt
//
LOCUS       DAJVBX010000110        14669 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.110, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000110 DAJVBX010000000
VERSION     DAJVBX010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 14669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14669
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.110"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            231..1306
                     /gene="citC"
                     /locus_tag="OPV72_002801"
                     /pseudo
     CDS             231..1306
                     /gene="citC"
                     /locus_tag="OPV72_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459616.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
     gene            1303..1599
                     /gene="citD"
                     /locus_tag="OPV72_002802"
     CDS             1303..1599
                     /gene="citD"
                     /locus_tag="OPV72_002802"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HCR9915050.1"
                     /translation="MKINQLAVAGTLESGDVMIRIAPLDTQDIDLQINSSVEKQFGEA
                     IRATILEVLSRYDVRGVQLNVDDKGALDCILRARLETLLARASGIAALPWEDRQ"
     gene            1596..2504
                     /gene="citE"
                     /locus_tag="OPV72_002803"
     CDS             1596..2504
                     /gene="citE"
                     /locus_tag="OPV72_002803"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HCR9915051.1"
                     /translation="MISASLQQRKTRTRRSMLFVPGANAAMVNNSFIYPADALMFDLE
                     DSVALREKDAARRLVYHALQHPLYRDVETIVRVNALDSEWGVNDLEAVVRGGADVVRL
                     PKTDTAQDVIDIENEILRIENACGREPGSTGLLAAVESPLGITRAVEIAHASERLIGI
                     ALGAEDYVRNLRTERSPEGTELLFARCAILQAARSAGIQAFDTVYSDANNEAGFLQEA
                     AHIKQLGFDGKSLINPRQIELLHNLYAPTRKEVAHARLVVEAAEAAAREGLGVVSLNG
                     KMVDSPVIERARLVLSRAELSGIREE"
     gene            2514..4043
                     /gene="citF"
                     /locus_tag="OPV72_002804"
     CDS             2514..4043
                     /gene="citF"
                     /locus_tag="OPV72_002804"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HCR9915052.1"
                     /translation="MTQKNESQRQDRVVAWSRHAESELSAYQSAAKLDLQAQKPRDHK
                     LCASLEEAIRRSGLRDGMTLSFHHAFRGGDLTINLVMETIAKMGFKNLTLASSSLSDC
                     HAPLVEHIRNGVVSRIYTSGLRGPLAEEISRGLLAEPVQIHSHGGRVHLVQSGELNID
                     VAFLGVPSCDEFGNANGYTGKACCGSLGYAMVDADSAKQVVMLTEQLLPYPHNPASIA
                     QDQVDLIVQIEEVGDANKIGAGATRMTTNPRELLIARSAAEVIAHSGYFNEGFSLQTG
                     TGGASLAVTRFLEDKMRSRNIVANFALGGITATMVNLHEKGLIRKLLDVQSFDRNAAQ
                     SLARNPNHIEISANQYANWGSKGASVDRLDVVVLSALEVDTHFNVNVLTGSDGVLRGA
                     SGGHCDTAVAAALSIIVAPLVRGRIPTLVDNVTTCVTPGSSVDILVTDHGIAVNPARP
                     ELAERLKAAGMKVVSIEWLRERAQLLTGQPRPIEFTDRVIAVVRYRDGSVIDVVHQVK
                     E"
     gene            4046..4492
                     /gene="citX"
                     /locus_tag="OPV72_002805"
                     /pseudo
     CDS             4046..4492
                     /gene="citX"
                     /locus_tag="OPV72_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459612.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
     gene            4464..5360
                     /gene="citG"
                     /locus_tag="OPV72_002806"
     CDS             4464..5360
                     /gene="citG"
                     /locus_tag="OPV72_002806"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HCR9915053.1"
                     /translation="MMPIPVNPTNASIQPQSLYDAWADLAWRAMLTEVNLSPKPGLVD
                     RLNCGAHKDMALADFHRSAEAIRHWLPRFMEYGASCTRLPPESVLAGLRPLGMACEAA
                     MFRATAGVNTHKGSIFSLGLLCAAIGRLYQLRQPIAAETLCATAADFCRGLTTRELRQ
                     NNLQLTAGQRLYQQLGLTGARGEAEAGYPLVIRHALPHYRALLAQGRDPELALLDTLL
                     LLMSLNGDTNVASRGGADGLRWLQQQAAVLLHQGGIRTPDDLVYLHRFDQQCIERNLS
                     PGGSADLLIVTWFLAQISQVNH"
     gene            5398..6963
                     /locus_tag="OPV72_002807"
     CDS             5398..6963
                     /locus_tag="OPV72_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000059035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anion permease"
                     /protein_id="HCR9915054.1"
                     /translation="MSLSKDNIWKLLAPLVVMGVMLLIPVPDGMPPQAWHYFAVFVAM
                     IVGMILEPIPATAISFIAVTICVIGSNYLLFDASELADPAFKASKQALKWGLAGFSST
                     TVWLVFGAFIFALGYEVTGLGRRIALFLVKFMGKRTLTLGYAIVIIDILLAPFTPSNT
                     ARTGGTVFPVIKNLPPLFKSFPNDPSARRIGGYLMWMMVISTSLSSSMFVTGAAPNVL
                     GLEFVSKIAGVQISWLQWFLSFLPVGIILLIVAPWLSYVLYKPEVTHSAEVAAWAGGE
                     LKNMGRLSRKEWTLIGLVLLSLGLWVFGGKIINATAVGLLAVSLMLALHVVPWKDITR
                     YNSAWNTLVNLATLVVMANGLTRSGFIDWFANTMSTHLEGFSPDATVIVLVLVLVLVL
                     VLVLVLVLVLVLVLVLVLVLVLVLVLVLVFYFAHYLFASLSAHTATMLPVILAVGKGI
                     PGVPMEQLCILLVLSIGIMGCLTPYATGPGVIIYGCGYVKSRDYWRLGAIFGVIYIAM
                     LLLVGWPILAMWN"
     gene            7073..7879
                     /gene="rna"
                     /locus_tag="OPV72_002808"
     CDS             7073..7879
                     /gene="rna"
                     /locus_tag="OPV72_002808"
                     /EC_number="4.6.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease I"
                     /protein_id="HCR9915055.1"
                     /translation="MNTIWHYSPLLAVLLTPIFAANADELQAQQYGDFTDYVLALSWQ
                     TGFCQSQHERRHREPDECRLQKEPANKADFLTVHGLWPGLPKSIAARGVDQRRWQRFG
                     CATRPIPNLPEVKASRKCSAPAPGLSPDIATALKEVMPGAGGNSCLERYEYAKHGACF
                     GFDPNAYFGTMIRLDKAIKDSALGQFLADNYGKTVSRAEFDSVVAQTWGQDNVKAVKV
                     NCHGNPAYLTEIQFSLKASMINAPLSSASFQPQPHPGNCGKQFIIDKAGY"
     gene            8114..8524
                     /gene="rnk"
                     /locus_tag="OPV72_002809"
     CDS             8114..8524
                     /gene="rnk"
                     /locus_tag="OPV72_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside diphosphate kinase regulator"
                     /protein_id="HCR9915056.1"
                     /translation="MSRPTIIINDLDAERIDRLLEQPAYADLPIADALNAELDRAQMC
                     SPQEMPNDVVTMNSRVKFRNLSDGETRVRTLVYPANMTDSSTQLSVMAPVGAALLGLR
                     VGDTIHWELPGGASTHLEVLELEYQPEAAGDFLR"
     gene            complement(8607..9845)
                     /locus_tag="OPV72_002810"
     CDS             complement(8607..9845)
                     /locus_tag="OPV72_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent formaldehyde
                     dehydrogenase"
                     /protein_id="HCR9915057.1"
                     /translation="MKALTYHGPHHVKVENVPDPGIEQPDDIILRVTATAICGSDLHL
                     YRGKIPQVKHGDIFGHEFMGEVVETGHDVKNIRKGDRVVIPFVIACGDCFFCRLQQYS
                     ACENTNDGHGAAMNKKQIPPPAALFGYSHLYGGVPGGQAEYVRVPKGNVGPFKVPPLL
                     SDDKALFLSDILPTAWQAAKNAQIQQRSSVAVFGAGPVGLLTIACARLLGAEQIFVVD
                     HHAWRLRFAEERYGAIPINFDDENDPAEKIIEQTAGHRGVDAVIDAVGFEAKGSMTET
                     VLTNLKLEGSSGKALRQCIAAVGRGGVVSVPGVYAGFIHGFLFGDAFDKGLTFKMGQT
                     HVHAWLGELLPLIEKGLLKPEEIVTHYMPFEEAARGYEIFEKREEECRKVILVPGAMS
                     AQAAQKQATGVINPMPGGVV"
     gene            10068..10496
                     /gene="uspG"
                     /locus_tag="OPV72_002811"
     CDS             10068..10496
                     /gene="uspG"
                     /locus_tag="OPV72_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspG"
                     /protein_id="HCR9915058.1"
                     /translation="MYKTIIMPVDVFEMELSDKAIRHAEFLAQQDGVIHLLHVLPGSA
                     SMSLHRFAADVRRFEEHLQHEAETRLQTMVGHFSIDPSRIKTHVRFGSVRDVVNEMGE
                     ELDADVVVIGSRNPSITTHLLGSNASSVVRHATLPVLVVR"
     gene            complement(10564..11331)
                     /locus_tag="OPV72_002812"
     CDS             complement(10564..11331)
                     /locus_tag="OPV72_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase anchor subunit
                     family protein"
                     /protein_id="HCR9915059.1"
                     /translation="MEKYELPLVFFTVLSQMSVGMALVLTWRTLRGEVEGQRFYWLAT
                     GLVLALASIAAILHLAHPDRAYNALINLRHAWLSREILGATLFGAAVGVTFLAKGHKA
                     MALIASVFGVLLVAVQGMTYAAPAMVAIANGFTMLLFFITVWVMGCAAIPLLRLRPAV
                     PALRQGIVVCIAVLIAAPLVWLSGGTVMQMTARSWLASPFYLASLVCLALAFVASRHG
                     DSRPKLLFVLLFVGVFLSRLVFFGDTVSTIVNIGHLY"
     gene            complement(11331..11888)
                     /locus_tag="OPV72_002813"
     CDS             complement(11331..11888)
                     /locus_tag="OPV72_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HCR9915060.1"
                     /translation="MRRAFLVNSDKCIGCRGCAMACKSFNQLEPDRFWRYVYPLDKDI
                     YPHEERAFYSLACNHCEHPACVAACPVEAYTKREDGVVVHNPERCIGCKNCIRNCPYG
                     APRFNEETRKAEKCSICYERLDIGMNPACVNACPVGALSIIDLDADPVPDNAVQYPPG
                     FPHMPQLNPGTRFILARQPKQPEDK"
     gene            complement(11885..14164)
                     /locus_tag="OPV72_002814"
     CDS             complement(11885..14164)
                     /locus_tag="OPV72_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HCR9915061.1"
                     /translation="MSNETGHLNRRSFLKGIVALGTVAALPGGLLTSRCALAQPPVPF
                     NPKTYKIYRNACPRNCYDTCSLKTWVKDGVITFVEGAPESTFTHGTPYVKGLSYPRRV
                     YSPDRIKYPMAQDVRGSGNWRRISWEEAMQRIAAKMLEIKKKDSSMLGLALTKYSGKF
                     GVLNYAVEGMMSSLGYTTRFAGTPCWPAGIDAQNYDMGDMWCNDPEDMVKAKYIIIWG
                     ANPAWCSMHSMKYIYQAREKGAKVVVIDPLLSQTAAKADLYLRVRPGSDGALALGMAR
                     HLVDKGLVDQDFVNNDAHGYPEFEAYLRNHVTVEWAAEICGLSAQVIRQLAEEFTAVN
                     PATAWIGYGMQRHVNGGANVRAIDAFVAMSGNIGVEGGGARYGHLHTWGFNYNAMLQK
                     PPVGAIGIPGAAGTTSEFGAAAGSDAVQYSDRSLNINQTAQGILEANDPPVRMLWVAC
                     KNPFAQDFDRSKMKKAFEKLEMVVCADQFFNETVQHADIVLPVTTAFEEWNVDASYWH
                     YWLSINQPAIKPMYEAKCDLEIATMLSRTINKMAPGSCTFPQEFDHKRWLDQEFNDGM
                     AKMFGISSWDDLLDGPKKAILPSSAAWYDRKFKTPSGKYEFKSELAEKNGHTALPEYK
                     PEAESKLPFHLFTPHVQFGLHSQFINLDWMQVFYPEPFVYIHPSSAKKKGISENDRVK
                     VFNNIGEVELRAKVTTNVPEDFLVMYEAWFPKRQYNVQNVVADTPADMGLMKTGAPGA
                     AIHSQFADVVLIGKGESVA"
     gene            complement(14235..>14669)
                     /locus_tag="OPV72_002815"
     CDS             complement(14235..>14669)
                     /locus_tag="OPV72_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HCR9915062.1"
                     /translation="TLRDFFNSHDSHSLKSAYVRLNPSAAVNLTDRAWLEAEYDFNAL
                     FVGPGKLLAAPFASVYLEEDALVMGKATLEIRDFMAALGLSVNQESNIPDDHISCVLE
                     LTTLLLANTRQTSQYCSTLTQYINNYLTKWVPLYIEKIKTHA"
BASE COUNT         3358 a         4122 c         3842 g         3347 t
ORIGIN      
        1 attaaaaaac ttaaaaccat aaaacactta aaaaccatct aacgctttgt gaaataaatc
       61 aaaatttacc accaaaatac tccttacgat gtatacgtca gagagaaaaa taaataactc
      121 gtcataaaaa tactcccact ctgactgaaa agaaaaagtt atcaagttgc aacacaacgc
      181 aacatataca gaaaagtggc aacaagcata tcaccaggat atttcttact atgtttggca
      241 ataatgtatt cactcgggta aaacgctctg aaaataaaaa atggcggaga tcgctcactt
      301 tctcaaagag aatgatttaa gcgtcgatac cactgtagaa gtgtttatta ccgtcagccg
      361 tgatgaccgt cttattgcct gcggcggtat tgccggaaat atcattaaat gcgtggccat
      421 tagcgaatca gtacgcggtg aaggcttagc gttaacgctg gcgacggaat tgattaatct
      481 cgcctgggaa cggcactgca cccatctttt tatttatacc aaaacggaat acgaagcgct
      541 gtttaaacag tgcagctttt cgacgatagc cagcgtccct ggcgtgatgg tcttaatgga
      601 aaatagcgcg acccggttga aacggtatgc ggaatcgctg gcgacattgc gtcacgaggg
      661 aaagaaaatt ggctgtattg tgatgaacgc caatcctttc acgcacggcc atcgctatct
      721 gatccaacag gcggcggcac agtgcgactg gctgcatctg ttcctggtca aagaagatac
      781 gtcacgcttt ccctatgaag accgactcga tctggtcctt aaagggacta ccgatatccc
      841 gcgcttaacc gttcatcgcg gctccgaata cattatttct cgtgcgacgt tcccctgcta
      901 tttcattaaa gagcagagcg tcattaatca ctgttatacc gaaatcgacc tgaagatttt
      961 ccgccagtat ctggcgcccg cgcttggcat cacacaccgc tttgtcggta cggagccgtt
     1021 ttgtaccgtt accgcccagt acaaccttga tatgcgtttc tggctggaga cgccaacgct
     1081 tcccgcccca cccattacgc tggtggaaat agagcggctt tgcttccagg agacgccgat
     1141 atccgcctcc tgggtacgca agctgctggt taaacacgat ctcacggcta tcgcgccgct
     1201 ggttcccgac gccaccctgc gctatttgca gggcatggtc gaacgccatc cgggcagcgc
     1261 ggcagcccgt caaaagtccc ccgtattagc aacaggtgaa aaatgaaaat aaaccagcta
     1321 gccgtcgcag gcacgcttga gtccggcgat gtgatgatac gcattgcgcc gctcgatacg
     1381 caggatattg acctgcaaat taacagtagc gttgaaaaac agtttggcga ggccattcgc
     1441 gccaccatcc tggaggtgct ttctcgctac gacgtgcgcg gcgtacaact gaacgtcgat
     1501 gataaaggcg ctctggactg cattttgcgc gcccgactgg aaacgctact ggcgcgcgcc
     1561 agcggtattg ccgctctgcc ctgggaggat cgccaatgat ttccgcctct ctgcaacaac
     1621 gtaaaacccg cacccgccgc agtatgttat tcgtaccggg cgccaacgcg gcgatggtga
     1681 acaattcgtt tatctacccg gccgacgcgc tgatgttcga cctggaagac tccgttgcat
     1741 tacgcgaaaa agacgcggcg cgccgtctgg tatatcacgc gctgcaacat ccgctttacc
     1801 gtgacgtcga aaccatcgtc cgcgtgaatg cgctggactc cgaatggggc gtcaacgatc
     1861 tggaagcggt cgtgcgcggc ggcgcggacg tggtgcgttt accgaaaacc gacaccgcgc
     1921 aggacgtcat tgatatcgaa aacgaaattc tgcgcattga aaacgcctgc ggtcgcgaac
     1981 cgggcagtac cggcctgtta gccgccgtgg aatcgccgct gggtattacc cgcgcggtag
     2041 aaatcgccca cgcctctgaa cggttgatcg ggattgcgct gggcgcggaa gactatgttc
     2101 gcaacctgcg caccgaacgc tctccggaag gcaccgaact gctgttcgcc cgctgcgcca
     2161 ttttgcaggc cgcgcgttcc gccggcattc aggccttcga taccgtctat tccgacgcca
     2221 acaacgaagc cggtttcctg caagaagccg cccacattaa acagttgggc tttgacggta
     2281 agtcactgat caacccccgc cagatagaac tgctgcacaa cctttatgcg ccgacgcgta
     2341 aagaggtcgc ccatgcgcgt ctggtcgttg aggccgcaga agccgccgcc cgcgaaggtc
     2401 tcggcgtcgt ttcccttaac ggcaagatgg tcgacagccc ggtgattgaa cgcgcccgtc
     2461 tggtgctctc ccgtgcagaa ctttccggta ttcgcgaaga ataaggcaaa aaaatgacgc
     2521 agaaaaatga atctcaacgc caggatcgcg tagtagcctg gagccgtcac gctgaaagcg
     2581 aactgagcgc ttaccaaagt gcggcaaaat tggatctaca agcgcaaaaa ccgcgcgacc
     2641 acaaactgtg cgccagcctg gaagaggcca tccgccgttc cggtttacgc gacggcatga
     2701 cgctttcctt tcaccacgct tttcgcggcg gcgatctgac gattaacctg gtgatggaaa
     2761 ccatcgcgaa gatgggcttc aaaaatctga ccctggcctc cagctcgctg agcgactgcc
     2821 acgcgccgct ggttgaacac attcgtaacg gggtggtcag ccgcatctac acgtcaggcc
     2881 tgcgcggccc gctggcggaa gaaatttctc gcggcctgct ggctgagccg gttcagattc
     2941 actcccacgg cggtcgtgtg catctggtac aaagcggcga actcaatatt gatgttgcgt
     3001 ttcttggcgt gccctcctgc gatgaattcg gtaatgctaa cggttatacc ggcaaagcct
     3061 gttgcggttc tctgggctac gcgatggtgg atgccgacag cgcgaagcag gtcgtgatgc
     3121 tgacggagca actgctgccg tatccgcata acccggcaag catcgctcag gatcaggttg
     3181 atctgatcgt gcaaatcgaa gaagtcggtg atgcaaacaa aatcggcgct ggcgcgaccc
     3241 gcatgaccac taatccgcgt gaactgctga tcgcccgcag cgcggcggaa gtcattgctc
     3301 actccggcta cttcaacgaa ggtttctccc tgcaaaccgg caccggcggc gcatcgctgg
     3361 cggtcacccg cttcctggaa gacaaaatgc gtagccgcaa cattgtggct aatttcgcgc
     3421 tgggcggtat caccgccacc atggtcaacc tgcatgaaaa gggcttaatc cgcaaactgc
     3481 ttgacgtgca gagcttcgat cgtaacgctg cgcaatcttt ggcccgcaac ccgaaccata
     3541 tcgaaatcag cgctaaccag tacgccaact ggggctctaa aggcgcttcc gtcgaccgtc
     3601 tggacgtggt ggtactgagc gcgctggaag tagacaccca cttcaatgtt aacgtgctga
     3661 ccggctccga cggcgttcta cgcggcgcgt ccggcggtca ctgcgatacc gccgtcgcgg
     3721 cggcgctgtc catcatcgtc gcgccgctgg tgcgcggtcg catcccaacg ctggttgata
     3781 acgtcaccac ctgcgtcaca ccgggctcca gcgttgacat tctggtcacc gatcacggta
     3841 tcgccgtcaa tccggcgcgt ccggagttgg ctgaacgcct gaaagcagcg ggaatgaaag
     3901 tggtatcgat tgagtggctg cgcgaacgcg cgcaactgct taccggtcag ccccgcccta
     3961 tcgaattcac cgaccgcgtg attgctgtcg tgcgttatcg cgacggttca gtgatcgatg
     4021 tggtgcatca ggtgaaggaa taagccacgc cactccactg gtctccttta ccgtggtggc
     4081 gccaggcccg atgaaagaca gcgcgttaac ccgccggatc tttaatcacg gcgtgactgc
     4141 cctgcacacg ctggcagaag agtatggctg gaccatccgg gagcaggctg cactggcttc
     4201 cgccagcggg ccggaagggt tgctggcgat tgacgcgccc gctcaggcgc tcaaacaggc
     4261 gaccatcgcg ctggaacagc gttatccact ggggcgcctg tgggatatcg atgtcctgac
     4321 ggcggaaggc gaaatactct ctcgccgcca tttcgcgctt cccgctcgcc gctgtctgct
     4381 gtgcgggcaa agcgcggctg aatgcgcgcg gggtaaaacc cacgcgctga ctgatttact
     4441 gactcatatg gaggcgctgc tgcatgatgc cgattcccgt caacccgact aacgcctcca
     4501 ttcagcctca gtcgctgtat gacgcctggg ccgatttggc ctggcgcgcc atgctgaccg
     4561 aggtaaattt atcgccaaaa cccggtctgg tagaccgact aaactgcggc gcgcacaaag
     4621 atatggcgct ggcggatttt caccgcagcg cggaggcgat tcgacactgg ctgccgcgct
     4681 ttatggaata tggcgccagc tgcacgcgcc tgccaccaga gtcagttctg gcgggcctgc
     4741 gtccattggg gatggcctgt gaagcagcga tgtttcgcgc aacggcgggc gtcaataccc
     4801 ataaaggcag cattttctcg ctggggttac tgtgcgccgc cattggccgc ctgtatcagc
     4861 tacgccagcc gatcgccgca gaaacactct gcgctaccgc cgccgatttt tgccgcggcc
     4921 tgaccacgcg cgaactgcgc cagaacaacc tacagctcac cgcaggccag cggctgtatc
     4981 agcaactggg attaaccggc gcgcgcggtg aagcggaagc gggctatccg ctggtcatcc
     5041 gccacgcgtt gccgcactac cgcgcattgc tggcgcaggg gcgcgatccg gaactggcgc
     5101 tgcttgatac cttactgctg ctgatgtcgc ttaacggcga taccaacgtc gcttcgcgcg
     5161 gcggggcgga cggtctgcgc tggttacagc agcaggcggc ggtcttatta catcagggcg
     5221 gcatacggac gcctgatgat ctcgtttatc tccaccggtt cgatcagcaa tgcattgaac
     5281 gcaatctcag cccaggcggt agcgccgatc tgctgatcgt gacctggttt ttagcgcaaa
     5341 tttcgcaagt taatcattaa cacaattata gaaaatatcc tttccggaga gtcatttatg
     5401 tctttatcca aagataatat atggaagttg ttggccccat tagtggtgat gggcgtcatg
     5461 ttgctaattc ctgttccaga tggtatgccg ccgcaggcct ggcactattt tgcggttttc
     5521 gtcgcgatga ttgtcggtat gatcctggag ccgatcccgg cgacagcgat cagttttatc
     5581 gccgtaacca tttgcgttat cggcagcaat tacctgctat ttgacgcttc agaactggcc
     5641 gatccggcgt ttaaagccag taaacaggcg ctgaaatggg ggcttgccgg tttctccagc
     5701 accacggtct ggctggtttt cggcgcgttt attttcgcgc tgggctacga agtgaccgga
     5761 ctggggcgcc gcattgcgct gtttctggta aaattcatgg gtaaacgcac gctgacgctc
     5821 ggctatgcga ttgtcattat cgatattttg ctggcgccgt ttactccctc caatacggct
     5881 cgtaccggcg ggactgtctt cccggttatc aagaacctgc cgccgctgtt taaatcgttt
     5941 ccaaacgatc cttccgcacg ccgcatcggc ggttatttga tgtggatgat ggtgatcagt
     6001 accagcctga gctcttcgat gtttgtcact ggcgcggcgc caaacgtgtt aggtctggag
     6061 ttcgtcagca agatcgccgg ggtccagatt agctggctgc agtggtttct cagctttctg
     6121 ccggtaggga ttattttact gatcgttgcg ccgtggctct cctatgtgct ttataaacct
     6181 gaagtgaccc acagtgcgga agtcgcggcc tgggctggcg gcgagttaaa aaacatgggg
     6241 cgtctgtccc gcaaagagtg gacgctgatt ggcctggtgc tgcttagctt aggattgtgg
     6301 gtttttggtg gaaaaatcat caacgccact gccgtgggtc tgctggccgt ctcgctgatg
     6361 ctggcgctgc atgttgtgcc gtggaaagat attacgcgct acaacagcgc ctggaacacc
     6421 ctggtgaacc tcgctacgct ggtggtcatg gccaatggct taacccgctc cggctttatt
     6481 gactggttcg ccaataccat gagtacgcat ctggaaggtt tctcgccgga tgcaaccgtc
     6541 attgtactgg tactggtact ggtactggta ctggtactgg tactggtact ggtactggta
     6601 ctggtactgg tactggtact ggtactggta ctggtactgg tactggtact ggtactggta
     6661 ttctatttcg cgcactattt gttcgccagt ctttccgctc acaccgcgac catgctgccg
     6721 gtcattctgg cggtgggtaa aggcattccg ggcgttccga tggaacaact gtgtattctg
     6781 ctggtgctgt ctatcggtat catgggctgt ctgacgccgt atgccaccgg ccctggtgtg
     6841 attatctacg gctgcggtta cgtgaaatcc agagactact ggcggcttgg cgcaatcttt
     6901 ggcgttatct atatcgcaat gctgttgctg gtgggctggc cgattctggc aatgtggaat
     6961 taaacattac gccaacgtag gttaaaaatg atgccgttca ggttcacctg agcggcattt
     7021 tttatgatta aatgagtaac attcataatg tctataaatt atcgaattca tcatgaacac
     7081 aatatggcat tacagtccgc tgctggctgt cctcttaacc ccgatttttg ccgccaacgc
     7141 cgacgaactt caggcgcaac agtacggtga tttcactgac tatgtgctgg cgctttcctg
     7201 gcaaaccggt ttttgtcaaa gccagcatga acgccgccat cgggaacccg atgagtgccg
     7261 tctgcaaaaa gagccagcca acaaagcaga ctttctgacc gtccacggcc tgtggccagg
     7321 attacccaaa tctatcgccg cacgcggtgt tgaccagaga cgctggcagc gctttggttg
     7381 tgcgacgcgg ccaatcccga atctgcctga agtcaaggcc agccggaaat gctccgcccc
     7441 cgcccccgga ctttcgcctg acatcgcgac agcgcttaag gaagtgatgc ccggcgcggg
     7501 ggggaattcc tgtctggagc gctacgaata tgccaaacat ggcgcctgtt tcgggtttga
     7561 tcccaatgcc tatttcggca ccatgatacg gctggataag gcgataaaag acagcgcgct
     7621 ggggcagttt ctggcggata attacggcaa gaccgttagc cgcgctgagt ttgatagcgt
     7681 cgtcgcacaa acgtggggcc aggataatgt caaagccgtt aaagtaaact gccatggcaa
     7741 tcccgcctat ttaacagaga ttcagttttc attaaaggcg tcgatgatta acgccccgct
     7801 ctcctctgcc tcattccagc cgcagccgca tcccggcaac tgcgggaaac agtttattat
     7861 cgataaagcc ggttattgac gaagcagagg tttaaaaccg tagccacatt tgagaacacg
     7921 cccgaatgta gactaaaatt cactcagggc tatgacgttt gaggatttac ccgaatgtga
     7981 actaaatcac ttcaaagacg gggtaagtct cagtatcatc atgagagtta aaccctcgcc
     8041 gccagacggt gagggttttc ttttgggacc atttacctgc actactcgca gtatcgatga
     8101 catggagtaa gaaatgtcca gacccactat tatcattaac gaccttgacg ccgaacgtat
     8161 tgatcgtctt ctggaacagc ctgcgtatgc ggatctgccg attgccgacg cgctcaacgc
     8221 cgaactggat cgcgcgcaaa tgtgttcgcc acaagagatg ccgaacgatg tcgtcaccat
     8281 gaacagccgc gttaaattcc gcaatttgag cgatggtgaa acacgcgtgc ggacgctggt
     8341 gtaccccgcc aatatgacgg acagcagtac ccagctttcg gtaatggcgc ccgtcggcgc
     8401 ggcgttgctg ggactgcgcg tcggcgacac cattcactgg gaactgccgg gcggcgcctc
     8461 cacccatctc gaagtgctgg aactcgaata tcagcctgaa gccgcgggcg acttcctgcg
     8521 ttaaaccatc tgcataagcg ttaatgcgtt tacacagagg atgcctgcgc atcctctttc
     8581 cgttagctct ttcatttctg cctgcttcag acaacgccgc ctggcatcgg gttgattact
     8641 cccgtcgcct gtttctgcgc cgcttgtgcc gacatcgctc ccggcaccag gataaccttc
     8701 cggcactctt cttcgcgttt ttcgaaaatt tcgtagccgc gcgccgcctc ttcaaacggc
     8761 atatagtgcg tgacaatctc ctccggcttc agcaaccctt tttcaataag cggtaataat
     8821 tcccccagcc acgcgtgaac atgggtttga cccattttaa aagttagccc cttatcaaag
     8881 gcgtcgccga ataaaaagcc gtgaataaaa ccggcataca cgccgggcac gctgaccacg
     8941 ccgccgcgtc ctaccgccgc gatacattgt cgcagcgctt tgccgctgct gccttccagt
     9001 ttaaggttcg tcagcaccgt ctccgtcatg ctgcctttcg cttcaaagcc tacggcatca
     9061 attaccgcgt ccacgccgcg gtgtcctgcc gtctgctcga tgattttttc cgccggatcg
     9121 ttctcatcat cgaagttgat cggtatcgcg ccgtaacgtt cttcggcgaa acgcaggcgc
     9181 caggcgtggt gatcaacgac gaagatctgc tccgcgccca gcagtcgcgc acaggcgata
     9241 gtcagtaatc ctaccggccc tgcgccaaaa accgccacgc tggaacgttg ctgaatctgg
     9301 gcattttttg ccgcctgcca ggcggtaggc aaaatatcag aaagaaacag cgctttatcg
     9361 tcagataaca gcggcggcac cttaaatgga ccgacattac cttttggcac gcgaacatat
     9421 tcggcctgtc cgccgggaac gccgccatac agatggctat aaccaaacag cgccgccggc
     9481 ggcgggatct gttttttatt catcgccgcg ccgtgtccgt cgttagtgtt ttcacacgct
     9541 gaatattgct gtagtcgaca gaaaaagcag tcgccacaag caatgacgaa cgggataaca
     9601 acccgatccc ctttccgaat attcttcaca tcatgtccgg tttccaccac ctcgcccata
     9661 aattcatggc cgaaaatatc accatgtttt acctgtggga tcttgccgcg atagagatgc
     9721 aaatcagatc cgcaaatcgc ggtggcggta acacgcaaaa tgatatcgtc aggctgctca
     9781 atgccgggat cgggtacgtt ttcaaccttt acgtgatgtg gaccgtgata cgtcaatgct
     9841 ttcatgcagc ctccggggta acggtgaatg ttgcgttcga ctataaaagg gtagctatcc
     9901 cggagagact accggaaaaa caggcggctt taggattttt cctggaaaat acacgacttt
     9961 tttaacgtca ggttgtcgca atatttaaaa ttgccagaca aatagcagaa agaaacatta
    10021 ttatatgctt gaataaattc agtattgatt aacagggagt aacgggtatg tataagacaa
    10081 tcattatgcc ggttgatgtt tttgaaatgg aacttagcga taaagccatt cgccacgctg
    10141 agtttctggc gcaacaggat ggcgtcattc atctgttgca tgtactgcct gggtccgcga
    10201 gcatgagtct gcaccgcttt gccgccgacg tgcgtcgctt tgaagaacat ttacagcatg
    10261 aggcggaaac gcgtctgcaa acgatggtgg gacacttcag tatcgatcct tcacgaatta
    10321 aaacgcatgt tcgctttggt agcgtgcgcg atgtcgtcaa tgagatgggc gaagaactgg
    10381 atgcggatgt cgtggtaatc ggttcgcgta atccgtctat cacgacacac ctgttggggt
    10441 ctaacgcctc aagcgtggtg cgccatgcga cgctgccagt attggttgtg cgttaaccct
    10501 ggtggctaaa aactgacacg ccctgccagg tcacgcctgg cagggctttt tactgcatca
    10561 tcgttagtac aaatgcccga tattcacaat agtactcacc gtgtcgccaa aaaagaccag
    10621 ccgactcaga aatacgccaa cgaataacaa gacgaacagg agtttcgggc gcgaatcacc
    10681 gtgacggctg gcgacaaaag cgagcgcaag gcaaaccagg cttgccagat aaaacgggga
    10741 agccagccat gaacgcgccg tcatctgcat gaccgttccc ccgcttaacc acaccagcgg
    10801 cgccgcgata agtaccgcga tacacaccac aattccctgg cgtaacgcag gaacggcagg
    10861 cctgagtctt aacagcggaa tcgccgcgca acccatgacc cataccgtaa taaaaaataa
    10921 cagcatggta aatccattag cgatagctac catcgctggc gcggcgtagg tcatcccctg
    10981 caccgccacc agtaacacgc cgaacacgga ggcgataaga gccatcgctt tatgtccctt
    11041 tgccaggaac gttacgccga ccgctgcgcc aaacaacgtg gcgccaagga tttcccgact
    11101 taaccaggca tgtcgcaggt taatcagcgc attataagcg cgatcgggat gcgccagatg
    11161 cagaatcgcg gcaatagacg ccaatgccag caccagcccg gtggccaacc aatagaaacg
    11221 ctggccttcc acttcaccac gcagcgtacg ccatgtcagt accaaagcca tcccgacaga
    11281 catctggctt aataccgtaa aaaacaccag cggcagttca tatttttcca ttacttgtcc
    11341 tccggctgct taggctggcg cgccagaata aagcgcgttc ctggattgag ctgtggcata
    11401 tgcgggaacc ctggcggata ctgcaccgca ttatcgggca caggatcggc atccaaatcg
    11461 ataatcgaca aggcgcccac cggacaggcg ttcacgcacg ccggattcat accgatatca
    11521 agacgctcgt agcatatact gcatttttcc gctttacgcg tctcttcatt aaaacgcggc
    11581 gcgccataag gacagttacg aatacagttt ttacagccga tgcagcgctc agggttatgc
    11641 accaccacgc catcttcacg tttggtatag gcttcgaccg gacaggcggc gacgcaggcc
    11701 ggatgttcgc agtggttaca ggccagcgag taaaacgccc gctcttcatg tggatagatg
    11761 tctttatcca acggataaac gtagcgccag aagcgatccg gctccagttg gttaaagctt
    11821 ttacacgcca tagcacagcc gcggcagccg atgcacttat cgctattcac taaaaacgca
    11881 cgtctcatgc tacggattcc cctttaccga tcaatacaac gtcagcaaac tgactgtgga
    11941 tagcggcgcc cggcgcgcca gttttcatca gccccatatc agcaggcgta tcggccacga
    12001 cgttttgcac gttgtactgc cgtttcggga accacgcttc atacatcacc agaaaatctt
    12061 ccggcacgtt ggtggtgact tttgcccgca gttccacctc gccaatgttg ttgaaaactt
    12121 tgacccggtc attttcgcta atgccttttt tcttcgcgga agaaggatgg atataaacaa
    12181 acggttccgg atagaacacc tgcatccagt ccaggttgat aaactgcgag tgcaggccaa
    12241 actgcacgtg cggcgtaaac agatggaaag gcagtttgct ctcggcttcc ggtttgtatt
    12301 ccggcagcgc ggtgtggccg tttttctccg ccagttcaga tttaaattca tacttgcctg
    12361 acggcgtttt gaacttgcga tcgtaccagg cggcagagct tggcaggatc gctttttttg
    12421 gcccgtccag cagatcgtcc caggaagaga tgccgaacat tttcgccata ccgtcgttga
    12481 actcctgatc cagccagcgc ttgtgatcga actcttgcgg gaaggtacag gaacccggcg
    12541 ccatcttatt aatggtgcgc gacagcatgg tagcgatttc aaggtcgcat tttgcttcat
    12601 acatcggctt aatcgccggc tgattaatgg aaagccagta gtgccagtaa gaagcatcca
    12661 cgttccactc ttcaaacgcg gtggtaacgg gcagcacgat atcagcgtgt tgcaccgttt
    12721 cgttgaagaa ctgatcggcg cagaccacca tttccagttt ttcaaacgct tttttcatct
    12781 tgctgcgatc gaaatcctgg gcaaacgggt ttttacaggc gacccacagc atacgaaccg
    12841 gcggatcgtt ggcctccaga atcccctgcg ccgtctggtt aatattcaga gagcgatcgg
    12901 agtactgcac ggcgtcgctg ccagcggcag ccccgaattc actggtggtg cccgccgctc
    12961 ccggtatgcc aatagcgccc accggcggct tctgcagcat ggcgttatag ttaaagcccc
    13021 aggtatgcag atggccataa cgcgcgccgc cgccttcgac accgatgttg ccggacatag
    13081 cgacaaaggc atcgatagcg cgaacgttgg cgccgccgtt gacatgacgc tgcatcccgt
    13141 aaccaatcca ggccgtggcc gggttaaccg ccgtaaactc ttccgccagt tgacgaatca
    13201 cctgtgccga caacccgcag atttctgccg cccactccac ggttacatgg ttacgcagat
    13261 aggcttcaaa ttccggatag ccatgagcgt cgttgttgac aaaatcctga tccaccaggc
    13321 ccttatccac cagatggcgc gccatcccca gcgccagcgc gccgtctgag ccaggccgta
    13381 cgcgcaggta gagatcggct ttggcggcag tctgcgacag cagcgggtcg ataaccacga
    13441 ccttcgcccc tttctcgcgc gcctgataga tatatttcat ggagtgcatt gagcaccagg
    13501 ctgggttcgc gccccagata atgatgtatt ttgctttcac catatcttcc gggtcgttac
    13561 accacatgtc gcccatgtcg tagttttgcg cgtcaatacc ggcaggccag cacggcgtac
    13621 cggcaaaacg ggtggtatag ccaagcgagg acatcatccc ttcaacggca tagttcagca
    13681 cgccaaactt accggaatat ttggtcagcg ccagaccgag catagaactg tcttttttct
    13741 taatctccag cattttggcg gcaatacgct gcatcgcctc ttcccatgag atgcgacgcc
    13801 agttgccgct accgcgaacg tcctgcgcca tgggatattt aatacgatcg ggactataaa
    13861 cccggcgcgg atagctcaac cctttgacgt aaggcgtacc gtgagtaaat gttgattccg
    13921 gcgcaccttc cacgaaagta atgaccccgt cctttaccca cgtcttgagg ctacaggtgt
    13981 catagcagtt acgcggacac gcgttacgat aaattttgta cgttttaggg ttaaagggaa
    14041 caggcggctg cgcaagcgcg catcgggagg tcagtaatcc tccgggtaaa gccgcaacgg
    14101 tgcccagcgc cactatcccc tttaaaaaag aacgtctgtt cagatgtccc gtctcattac
    14161 tcatattgat actctcgttt taattcatca aaccaataaa ataagatgtc cgccaccgta
    14221 tataacgtgg tcgtttatgc atgagttttt attttttcga tatataatgg cacccacttt
    14281 gttaaatagt tattgatata ttgagtgagg gtagagcagt attgtgacgt ttgccgggta
    14341 ttagccagta atagtgtggt caattccagc acgcaggaaa tatgatcgtc aggaatattg
    14401 ctttcctgat taaccgataa tcccaacgct gccataaaat cccgtatctc cagcgtcgcc
    14461 tttcccatca ccagcgcatc ctcttccaga tacactgaag cgaaaggcgc agccagcagc
    14521 ttgccagggc cgacgaatag cgcattaaag tcatactccg cttccagcca cgcccggtcg
    14581 gtaaggttta ccgcagcaga tggatttaat ctcacgtagg cagatttcag tgaatgacta
    14641 tcatgagaat taaaaaaatc acgcaatgt
//
LOCUS       DAJVBX010000111        14619 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.111, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000111 DAJVBX010000000
VERSION     DAJVBX010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 14619)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14619)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14619
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.111"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(156..1061)
                     /locus_tag="OPV72_002816"
     CDS             complement(156..1061)
                     /locus_tag="OPV72_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001574833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HoxN/HupN/NixA family nickel/cobalt transporter"
                     /protein_id="HCR9915063.1"
                     /translation="MLSAAILAYSFGLRHAVDADHIAAIDTVTRKLMQQGKTPLGVGA
                     FFSLGHSTIVVLACLAIVVTSMAFRDRIDVLHQYGSLIGTAVSAFFLLAMALLNLFIL
                     FNVWRQFRSVTRGESVGAHDEAIPGGLMTRIFQRTFRLVTSSWHMYFVGFLFGLGFDT
                     ATEVGLLGISASAANQGLSLWSMMIFPVLFTAGMALVDSLDNFVMVGAYGWAFSHPLR
                     KLYYNITITAASVIVALAIGGLEALGLIDDALQLSGTFWQTVSTLNDHMGNVGFWVVG
                     AFVLFWLLSLLNYRWRGYDKITLNT"
     gene            complement(1302..2717)
                     /locus_tag="OPV72_002817"
     CDS             complement(1302..2717)
                     /locus_tag="OPV72_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCR9915064.1"
                     /translation="MKWVKPQSLYLQLLLFLGLPLILLWGLSAFNSYVNALQAATQAY
                     DRTLLSSARTVSERLVVRNNHLEVNVPWVVLDSFELNMNDRLYYKVVDPSGKVISGYD
                     DLPAMPPATPRTRLYPALAWFYHTEYRGEAIRVARLLQPVNEGGIIGMAEVYVAETLQ
                     SRRYLAGQLLFSSWISQGLLVLLTLVLVGWLLRRILRPMRQLSSLMVRREPGLLTPLP
                     ELLPWSETRLLIVAFNRYIDRLRGILSRQERFSADASHQLKTPLAVLKTQAAVALASQ
                     HPHHWYESLQAMSVTLDSTIQLTERLLQLSAVKHKEQGERRFSPVNLYDIVQSGCFTR
                     LAQARSKHIDLGYEGEQEAMWIEGDEVLLSELCGNLLDNALKYTPEQGIVTARLERDG
                     DAVTLVVEDSGPGIDNEHIHLALQPFHRLDNVGNVAGAGIGLALVNDIARLHRTHPHF
                     SRSEALGGLYVRIRFLSLVPQ"
     gene            complement(2704..3378)
                     /gene="tctD"
                     /locus_tag="OPV72_002818"
     CDS             complement(2704..3378)
                     /gene="tctD"
                     /locus_tag="OPV72_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator TctD"
                     /protein_id="HCR9915065.1"
                     /translation="MRLLLAEDNRELAHWLEKALVQNGFAVDCVFDGLAADHLLHSEM
                     YALMVLDINMPGMDGLEVVQRLRKRGQTLPVLLLTARSAVADRVKGLNVGADDYLPKP
                     FELEELDARLRALLRRSAGLVHEVQQLGELIFHDEGYFLLQGQPLALTPREQALLTVL
                     MYRRTRPVSRQQLFEQVFSLNDEVSPESIELYIHRLRKKLQGSDVRITTLRGLGYVLE
                     RGDEVG"
     gene            3533..4342
                     /locus_tag="OPV72_002819"
     CDS             3533..4342
                     /locus_tag="OPV72_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tripartite tricarboxylate transporter substrate
                     binding protein"
                     /protein_id="HCR9915066.1"
                     /translation="MKKQLLRTLTASILLMSTSVLAQEAPSRTECIAPAKPGGGSLLN
                     LSQGKFGRYGVDDVRWLASVGTDYGMIAVRADSPWKTLKDLMTAMEKDPNSVVIGAGA
                     SIGSQDWMKSALLAQKANVDPHKMRYVAFEGGGEPVTALMGNHVQVVSGDLSEMVPYL
                     GGDKIRVLAVFSENRLLGQLANVPTAKEQGYDLVWPIIRGFYVGPKVSDADYQWWVDT
                     FKKLQQTDEFKKQRDLRGLFEFDMTGQQLDDYVKKQVTDYREQAKAFGLAK"
     gene            4354..4788
                     /locus_tag="OPV72_002820"
     CDS             4354..4788
                     /locus_tag="OPV72_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461713.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tripartite tricarboxylate transporter TctB
                     family protein"
                     /protein_id="HCR9915067.1"
                     /translation="MMSDRIFAGIWLLLCIAGLFIAWQIQSEYSYEPVGPRPFPLGII
                     GLMALCALALLLRHPDTVSWPRRHVLQKLITMIIILLMYAWGFEWLGFPIATALLTMV
                     IGMLFGATIPAAGISGAVLGILLWYAFDRLLDVTLPLGAWLS"
     gene            4799..6313
                     /locus_tag="OPV72_002821"
     CDS             4799..6313
                     /locus_tag="OPV72_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003846009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tripartite tricarboxylate transporter permease"
                     /protein_id="HCR9915068.1"
                     /translation="MDTWICLSQGFAVAMTPENLVIALIGCFVGTIVGLLPGLGPING
                     VAILLPLAFALHLPAESALILLATVYIGCEYGGRISSILLNVPGDAAAIMTALDGYPM
                     AQQGKGGVALSISAVSSFFGSLIAIGGIILFAPLLAQWSLAFGPAEYFALMVFAIACL
                     GSMMAQNPLKSFLAALIGLGLATVGVDANTGVYRFTFDSVHLSDGVQFIVVVIGLFSV
                     SEILLMLEHTSSGQTMVRKTGRMLFNLKEGAQCIGTTLRSSVIGFFVGVLPGAGATIA
                     SAITYMTEKKLSGNSDSFGKGDIRGVAAPEAANNASACGSFIPMLTLGVPGSGTTAVM
                     MGALTLYNITPGPAMFTEQPDIVWGLIAALLIANVMLLIMNIPLIGLFTRMLTIPLWF
                     LVPAIAAVSAVGVYAVHSPTFDLVLMVALGVLGYILRKMHFPMSPLILGCVLGEMLEQ
                     NLRRALSISNGNMAILWQSGVAKALLIMAIIVIVVPPVLRLIRKHSRKPQVDAS"
     gene            6616..7593
                     /gene="csiD"
                     /locus_tag="OPV72_002822"
     CDS             6616..7593
                     /gene="csiD"
                     /locus_tag="OPV72_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417145.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation induced protein CsiD"
                     /protein_id="HCR9915069.1"
                     /translation="MNALTAVKANTDDLAQRHTGFILAPSAQSPRLLALTFTADTTRQ
                     FLHQVAQWPVQALEYKSFLRFKIGKILDDLCGNQLQPLLIKTLLNRAQGALLISAEGI
                     DDVAQAEEMVKLATAVAHLIGRSNYDAMSGQYYARFVVKNVDNSDSYLRQPHRVMELH
                     NDGTYVEEVTDYVLMMKIDEQNMEGGNSLLLHLDDWEHLESFFTHPLARRVMRWAAPP
                     SKNVSHDVWHPVFDVDQQGRPVMRYIDQFVQPKDFEEGVWLSELSDALETSQNILSVP
                     VPVGKFLLINNLFWLHGRDRFTPHPDLRRELMRQRGYFAYAASHYQTHQ"
     gene            7619..8887
                     /gene="lhgO"
                     /locus_tag="OPV72_002823"
     CDS             7619..8887
                     /gene="lhgO"
                     /locus_tag="OPV72_002823"
                     /EC_number="1.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-2-hydroxyglutarate oxidase"
                     /protein_id="HCR9915070.1"
                     /translation="MYDFVIIGGGIIGMSTAMQLIDVYPDARIALLEKESAPACHQTG
                     HNSGVIHAGVYYTPGSLKARFCLAGNQATKTFCDQNNIRYDTCGKMLVATSELEMARM
                     RALWERTAANGLEREWLNAAELREREPNIIGLGGIFVPSSGIVSYRDVATAMANRFQA
                     KGGEIIYHAEVSALTEHAAGVIIRTSQGREIETATLIGCAGLMADRLVKMLGVEPGFI
                     ICPFRGEYFRLAPRHNRIVNHLIYPIPDPAMPFLGVHLTRMIDGSVTVGPNAVLALKR
                     EGYRKRDVSFTDTLEIFRSAGIRRVLQNHLLSGLGEMKNSLCKSGYLRRVQKYCPSLT
                     VNDLQPWPAGVRAQAVSPDGKLIDDFLFVTTPRSIHTCNAPSPAATSAIPIGAHIVSK
                     VQALRASQSNPGRTLRAARSVDALHAAFTR"
     gene            8909..10357
                     /gene="gabD"
                     /locus_tag="OPV72_002824"
     CDS             8909..10357
                     /gene="gabD"
                     /locus_tag="OPV72_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent succinate-semialdehyde
                     dehydrogenase"
                     /protein_id="HCR9915071.1"
                     /translation="MQLNDSTLFRQQAFIDGDWRDARGGDVIPVSNPANGKPLGNVPK
                     MGAEETRDAINAANRALPAWRALTAKERANILRRWFNLMMEHQDDLARLMTLEQGKPL
                     AEAKGEISYAASFIEWFAEEGKRIYGDTIPGHQTDKRLLVIKQPIGVTAAITPWNFPS
                     AMITRKAGPALAAGCTMVLKPASQTPFSALALAELAQRAGILAGVFNVVTGSAGDIGG
                     ELTSNPLVRKLSFTGSTEIGRQLMEQCAKDIKKVSLELGGNAPFIVFDDADLDKAVEG
                     ALASKFRNAGQTCVCANRLYVQDGVYDRFAEKLNQAVNKLAVGDGLQADVAIGPLIDE
                     KAVAKVQEHIADALEKGARVITGGEAHKLGGNFFQPTILADVPDNAKVAKEETFGPLA
                     PLFRFSDEADVIRQANDTEFGLAAYFYARDLSRVFRVGEALEYGIVGINTGIISNEVA
                     PFGGIKASGLGREGSKYGIEDYLEIKYMCIGL"
     gene            10372..11655
                     /gene="gabT"
                     /locus_tag="OPV72_002825"
     CDS             10372..11655
                     /gene="gabT"
                     /locus_tag="OPV72_002825"
                     /EC_number="2.6.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-aminobutyrate--2-oxoglutarate transaminase"
                     /protein_id="HCR9915072.1"
                     /translation="MNTNNTLMQRCHNAVPRGVGQIHPIFAERAENCRVWDVEGREYL
                     DFAGGIAVLNTGHLHPGIVSAVEAQLKKLSHTCFQVLAYEPYLALCERMNQKVPGDFA
                     KKTLLVTTGSEAVENAVKIARAATKRSGAIAFSGAYHGRTHYTLSLTGKVHPYSAGMG
                     LMPGHVYRALYPCPLHNISDDDAIASIERIFKNDAAPEDIAAIIIEPVQGEGGFYAAS
                     PAFMQRLRALCDQHGIMLIADEVQSGAGRTGTLFAMEQMGVAADITTFAKSIAGGFPL
                     AGVTGRADVMDAIAPGGLGGTYAGNPIACVAALAVLDIFEQENLLQKANTLGKTLRDG
                     LMEIAETHREIGDVRGLGAMIAIELFENGDPGKPNATLTADIVARAREKGLILLSCGP
                     YYNILRILVPLTIEASQIRQGLEIIAQCFDEAKQA"
     gene            11785..13185
                     /gene="gabP"
                     /locus_tag="OPV72_002826"
     CDS             11785..13185
                     /gene="gabP"
                     /locus_tag="OPV72_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GABA permease"
                     /protein_id="HCR9915073.1"
                     /translation="MGQLSESHALGGGLKSRHVTMLSIAGVIGASLFVGSSVAIAEAG
                     PAVLLAYLFAGLLVVMIMRMLAEMAVATPDTGSFSTYADKAIGPWAGYTIGWLYWWFW
                     VLVIPLEANIAAIILNSWIPGIPVWLFSLVITLALTGSNLLSVKNYGEFEFWLALSKV
                     IAILAFIALGAAAISGFYPYAEVSGISRLWDHGGFMPNGFGAVLSAMLITMFSFMGAE
                     IVTIAAAESDTPDKHIVRATNSVIWRISIFYLCSIFVVVALIPWNMPGLKSVGSYRSV
                     LELLHIPHAKFIMDCVILLSVTSCLNSALYTASRMLYSLSRRGDAPAIMGKTNRSKTP
                     WVAVLLSTGAAFLTVIVNYYAPAKVFKFLIDSSGAIALLVYLVIAISQLRMRKILLAQ
                     GGEIKLKMWLYPWLTWLVIGFICFVLVVMLFRPAQQLEVISTGLLGLGIIGTVPIMSR
                     WKKLIRWQKAPLQNLR"
     gene            13227..13904
                     /gene="csiR"
                     /locus_tag="OPV72_002827"
     CDS             13227..13904
                     /gene="csiR"
                     /locus_tag="OPV72_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator CsiR"
                     /protein_id="HCR9915074.1"
                     /translation="MTALSQPTAIDGYRWLKNDIIRGTYQPDEKLRMSLLTARYALGV
                     GPLREALSQLVAERLVTVVNQKGYRVASMSEAELLDIFDARANMEAMLVRLAIERGDD
                     AWEAEILARAHMLSKLEASDASEHMLDEWDQRHQAFHSAIVAGCGSHYLLQMRERLFD
                     LAARYRFIWLRETVLSVEMLEDKHIQHHTLTEAILAREAARASELMRQHLLTPIPIIR
                     QAMAGKM"
     gene            complement(13926..14375)
                     /gene="lysM"
                     /locus_tag="OPV72_002828"
                     /pseudo
     CDS             complement(13926..14375)
                     /gene="lysM"
                     /locus_tag="OPV72_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461721.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding protein LysM"
     gene            complement(14475..>14619)
                     /locus_tag="OPV72_002829"
     CDS             complement(14475..>14619)
                     /locus_tag="OPV72_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="YqaE/Pmp3 family membrane protein"
                     /protein_id="HCR9915075.1"
                     /translation="IVFTIILPPLGVLLGKGFGWAFILNILLTLLGYIPGLIHAFWVQ
                     MRH"
BASE COUNT         3353 a         4043 c         3919 g         3304 t
ORIGIN      
        1 tttggtattg tatgttatat cggattgctt aaattgataa cgaaaggcaa gcatgaaaaa
       61 taacgcactt accgggaaga atatactctc aggagataaa atgcttcggc aatgatatga
      121 caccactgcc gaaatgctat ttttacagaa atcaatcagg tattgagggt gattttatca
      181 tagccgcgcc agcgataatt caacaacgag agcagccaga atagcacaaa agcacccact
      241 acccagaagc ccacattccc catatgatcg ttaagcgtgc tgacggtctg ccaaaatgtt
      301 ccgcttaact gtaacgcatc atcaatcaac cccagcgctt caagcccgcc aatcgccagc
      361 gcgacaatga cggatgcggc ggtaatggtt atattataat aaagcttacg taatggatgc
      421 gagaaagccc aaccgtaagc gccgaccatg acaaagttat ccagggaatc taccagcgcc
      481 atcccggcgg taaacagcac aggaaaaatc atcattgacc agagagatag cccctggtta
      541 gctgctgaag cggaaatgcc cagcaaccca acctcggttg cggtatcaaa tcccaagcca
      601 aacagaaaac cgacaaaata catatgccaa ctggaagtga ccaaacgaaa cgtacgctga
      661 aatatacgcg tcatcagccc gccaggtatc gcctcgtcat gcgcccccac tgactcgccg
      721 cgggtaaccg agcgaaattg ccgccagacg ttgaacaaaa taaacaggtt gagcagggcc
      781 atcgccagca gaaaaaaagc ggaaacagcc gtaccaatca acgaaccata ttgatgcaaa
      841 acatcaatac gatcgcgaaa tgccatcgac gtcacaacaa tcgccagaca tgccagaacg
      901 acaatggtcg aatgacccaa tgaaaaaaac gcccccacgc ctaaaggcgt tttaccctgc
      961 tgcatcagtt tacgggtgac ggtatcgatg gctgcgatat gatcggcatc aaccgcatga
     1021 cgcagcccaa agctatacgc cagtatggct gcgcttagca tgactgcatg gtgatgaaaa
     1081 acacagaacg cccaaatcta ggccaggatg ttaaccccga caagaaagac ggttaatgct
     1141 attccccgtc gtttagtatg attattcatg cccctgcacc cactatagtt ttaattaacg
     1201 ctacggtttg tagggggaat gtatgatcat ttgattaaaa cgtcacacct caagatgcga
     1261 ctttttgtaa acgtgcttta ccgctgacac atttgtgcgc attactgcgg gacaaggctt
     1321 aaaaagcgta tccgaacgta taaccctccc aacgcttcgc tacgggaaaa atggggatga
     1381 gtacggtgca agcgtgcgat atcattgacc aaagccagac caatgcccgc cccggccaca
     1441 tttcctacgt tatcgagccg gtggaacggc tgtagcgcca gatggatgtg ttcattatca
     1501 atgccggggc cgctatcttc gacaaccagc gtcacggcat cgccatcccg ttcaagccgc
     1561 gcggtgacaa tgccttgctc aggcgtgtat ttcagcgcat tatccagcaa gtttccgcac
     1621 agctcgctaa gcagtacctc atccccctcg atccacatcg cttcctgttc gccttcgtag
     1681 cccaggtcga tatgtttact gcgcgcctgc gccaggcggg taaagcagcc gctctgtacg
     1741 atatcgtaca gattcaccgg ggaaaaacgc ctctcgccct gctctttatg ctttaccgca
     1801 gaaagttgca acaatctttc cgtgagctga atggtgctat ccagcgttac gctcatcgcc
     1861 tgcagacttt cgtaccagtg atgagggtgc tggctggcta acgccaccgc cgcctgcgtt
     1921 tttaacaccg ccagcggcgt ttttaactgg tgagaagcat cggcgctaaa gcgttcctgc
     1981 cgggaaagga tgccgcggag cctgtcaatg tagcgattaa acgccacgat taacaagcgt
     2041 gtttccgacc acggcagcag ttccggcagc ggcgttaaca gacccggttc gcggcgtacc
     2101 attaatgacg aaagttgacg catagggcgc aggatccggc gtaataacca gccaaccagc
     2161 accagggtca gcaacaccag cagcccctgt gagatccagg aagagaacag cagttggccc
     2221 gccagataac gacgggactg cagcgtttct gcgacataaa cctccgccat gccgataatg
     2281 ccgccttcgt tgaccggctg tagcaaacgc gctacgcgga tcgcctcgcc gcgatactcg
     2341 gtatgataga accacgccag cgccggataa agccgggtac ggggcgtagc gggcggcatg
     2401 gcaggcagat cgtcataacc ggaaatgacc ttcccggaag ggtcgacgac tttgtaatag
     2461 agtcgatcat tcatattaag ctcgaagcta tccagcacca cccagggcac gttaacttcc
     2521 agatggttat tgcgcaccac cagccgttcc gataccgttc gcgccgagga gagcaacgta
     2581 cgatcataag cctgagtggc ggcctgtagc gcattgacat aactgttaaa cgccgacagc
     2641 ccccatagca gaatcagcgg caaccccagg aacagtaaga gttgcaggta caacgattgc
     2701 ggcttaaccc acttcatcgc cgcgctccag cacataaccc aggccgcgca gcgtcgtaat
     2761 tcgtacatcg cttccctgaa gttttttacg cagtcgatga atataaagtt cgatgctttc
     2821 agggcttacc tcatcgttca ggctgaacac ctgttcaaaa agctgctgac gcgagacagg
     2881 ccgcgttcgt cggtacatca atacggttaa gagcgcctgc tcacgcggcg tcagcgctaa
     2941 cggctgtccc tgtaacagaa aatacccttc atcatgaaag atcaattcac ccagttgctg
     3001 aacttcatga accagcccag cgctgcgtcg gagcaaggcc cgtaaacggg catccagctc
     3061 ttccagttca aagggtttcg gcagatagtc atccgcgccg acgttgagac cttttacgcg
     3121 atccgccacc gcgcttcgcg ccgtgagcag caaaacgggc aaggtctgac cgcgtttacg
     3181 cagccgttgc accacctcca gtccatccat tcccggcata ttgatatcca gcaccatcag
     3241 cgcatacatt tcactgtgca gaagatggtc agccgccagg ccgtcaaata cgcagtccac
     3301 ggcaaagccg ttttgcacca gcgctttctc cagccagtga gccagctcac ggttatcttc
     3361 cgccaataag agacgcatat cacatcctgt aaagtttctg ccgcattgaa agggaattga
     3421 aaggttattg ttttaacaat cacgcaaccg aactgctaca tgtcggctca cataatcaca
     3481 aaaatcttct tccgaacctg aaaaatccgg acgtccggcg tgaggataaa aaatgaaaaa
     3541 acaattactt cgtaccctta ctgcaagcat tttattaatg agtacctctg ttctggcaca
     3601 ggaggcgccg tcgcgaacgg aatgtatcgc gccagccaaa cctggcggcg gttcgctgct
     3661 caacctgtcg caggggaaat ttggtcgcta cggcgtggat gatgtgcgct ggctggcaag
     3721 cgtgggcact gattacggca tgatcgccgt gcgtgcggat tccccgtgga agacgctgaa
     3781 agatctgatg acggcgatgg aaaaagatcc caacagcgtg gtcatcggcg ctggcgcctc
     3841 tattggcagc caggactgga tgaagtcggc gttgctggcg caaaaggcga acgtcgatcc
     3901 gcacaagatg cgctacgttg cctttgaggg cggcggcgag ccggtgacgg cattaatggg
     3961 caaccatgtt caggttgtct ccggcgatct cagtgaaatg gtgccttatc tgggcggcga
     4021 caaaatccgc gtccttgccg tcttttcaga aaatcgtctg ctgggccagc ttgccaatgt
     4081 ccctaccgct aaagaacagg gctacgacct agtgtggccg attattcgcg gcttctatgt
     4141 cgggcccaaa gtcagcgatg ccgattacca gtggtgggtg gataccttca agaagctcca
     4201 gcaaaccgac gagtttaaaa agcagcgcga tctgcgcggc ctgtttgagt tcgacatgac
     4261 cggccagcag ctcgatgact acgtgaaaaa acaggttact gattaccgtg aacaggcgaa
     4321 agccttcgga ctcgcgaaat aatcgcggag gcaatgatga gcgatcgtat ctttgcgggt
     4381 atctggctgt tgctctgtat cgccgggcta ttcatcgcct ggcagatcca aagcgaatac
     4441 agctatgaac ccgtcggccc ccgccctttt ccgctgggga ttatcggcct gatggcgctc
     4501 tgcgcgctgg cgctgttatt gcgccatccc gacacggtga gctggccgcg ccgccatgtt
     4561 ctgcaaaagc taattaccat gatcatcatc ctgttgatgt atgcctgggg attcgaatgg
     4621 ctgggttttc ccatcgccac cgcgcttctc accatggtta tcgggatgct gttcggcgcc
     4681 acgattccgg cggcgggtat ctccggcgcg gtattaggca ttctgctgtg gtatgccttt
     4741 gaccggctgc ttgatgtcac cttacctctc ggcgcctggc tgagttaacg gagcaacgat
     4801 ggatacctgg atatgtcttt ctcagggctt tgcggtggca atgacgccgg aaaacctggt
     4861 tatcgcgttg attggctgct tcgtgggcac gatcgtcggt ctgctgccgg gcctgggacc
     4921 gatcaacggc gtggcaatct tactgccgct ggcctttgcg ttgcatctgc ctgcggagtc
     4981 ggcgctaatt ctgctggcga cggtgtacat tggctgtgag tatggcggca ggatctcctc
     5041 catattgctc aacgtccccg gcgatgcggc ggcgatcatg acggcgctgg acggttaccc
     5101 aatggcgcag caagggaaag gcggcgtagc gctgtcgatt tccgcagtca gctcattttt
     5161 cggttcatta atcgctatcg gcggcatcat tctgttcgcc cctttactgg cgcaatggtc
     5221 gctggccttc ggtccggcgg aatatttcgc cttaatggtt tttgctatcg cctgtcttgg
     5281 cagcatgatg gcgcaaaacc cgcttaaatc atttctggca gctctgatcg gtcttggcct
     5341 tgcgaccgtc ggcgtggacg ccaacaccgg ggtttatcgc tttacctttg acagcgttca
     5401 tctttccgac ggcgtacagt ttatcgtcgt ggtgatcggc ctgttctcgg tatcagaaat
     5461 acttttaatg ctggaacata ccagcagcgg gcaaacaatg gtccgcaaaa cgggtcgaat
     5521 gttgttcaac ctgaaagaag gcgcgcagtg tatcggcacc accctgcgtt cttcggtaat
     5581 cggctttttt gtcggcgtat tgcccggcgc cggggcgacc attgccagcg ccattaccta
     5641 tatgaccgag aaaaaactca gcggcaacag cgatagcttc ggcaaagggg atattcgcgg
     5701 cgtcgcggcg ccggaggcgg caaacaacgc ctctgcctgc ggctccttca tcccgatgct
     5761 gacgctgggc gttcccggtt ccggcactac ggcagtgatg atgggggcgc tgacgctgta
     5821 taacatcacg ccaggcccgg cgatgttcac cgaacagccg gatatcgtct ggggactcat
     5881 cgctgcgctg ctgattgcga acgtgatgct gctgatcatg aatatcccgt tgatcggtct
     5941 gttcacccgt atgctcacca ttccgctgtg gttcctggta cccgccatcg ctgccgtatc
     6001 ggcggtaggg gtatatgcgg tacacagccc caccttcgat ctggtgctga tggtcgcgct
     6061 tggcgtgtta gggtacattt tacgtaaaat gcacttcccc atgtcgccgc tgatcctggg
     6121 atgcgtactg ggggaaatgc tggagcagaa cctgcgtcgc gcactctcca tcagtaacgg
     6181 caatatggcg attttgtggc aaagcggcgt tgccaaagcc ctgctgatca tggcgatcat
     6241 agtcattgtc gtaccgccag tgttacgtct gatccgtaaa cacagccgta aaccgcaggt
     6301 tgacgccagt taattgactg ctgaaatacg ttgtacttgt ccggcctacg cgctcatgtg
     6361 ccaggccggg caaccccgcc agcatcactc tttccataac tcgctcattt tacacccctt
     6421 cttgccgttg tcaggctcgt ggcgccgtta acctcacctt tcgcattgtt aaatatttgt
     6481 tgtttttgat cacaataatt aaacaaaagc ggttatttca tacgcgttcc tggaaaatgt
     6541 cgatattttt aatttatggc tacgaaatga gcatcgccat gtctccctga ccatctaccg
     6601 agaggaatga ttctgatgaa tgcactgact gccgtaaaag cgaacacaga tgatttagcc
     6661 caacgccata ctggtttcat ccttgcccct tcggcgcagt cgccgcgcct gctggcgtta
     6721 acgtttacgg cggataccac aagacaattt ctccatcagg ttgcgcagtg gccggtgcag
     6781 gcgctggaat acaaatcttt cttacgtttc aaaatcggca agatcctcga cgatctgtgc
     6841 ggcaatcagc tacaaccgct gttgatcaaa acgctcctca accgtgcaca aggcgcgctg
     6901 ttgatcagcg ccgaagggat cgatgatgtc gcacaggcag aagagatggt caaactggcg
     6961 acggcggtgg cgcatcttat tggtcgctcc aactacgatg cgatgagcgg ccagtattac
     7021 gcgcgtttcg tggtcaaaaa cgtcgacaac tccgacagtt atctgcgcca gccccaccgc
     7081 gtaatggaac tgcacaatga cggtacctat gttgaggagg tgaccgacta cgtgctgatg
     7141 atgaaaatcg acgaacaaaa tatggaaggc ggtaattcgc tgctgctgca ccttgatgac
     7201 tgggaacatc tggagtcgtt ttttacccat ccgctggcgc gtcgcgtcat gcgctgggcg
     7261 gcgccgccaa gcaagaatgt tagccatgac gtctggcacc cggtgtttga tgtcgaccaa
     7321 caaggccgcc cggtcatgcg ttatatcgac cagttcgtcc agccaaaaga ctttgaagaa
     7381 ggcgtctggc tcagcgagct ttcagacgcg ctggaaacca gtcaaaacat cctctccgtg
     7441 ccggtaccgg tcggcaaatt cctgctgatt aacaatctgt tctggctaca tggacgcgat
     7501 cgttttacgc cgcatcctga cttgcgtcgc gagctgatgc gccagcgcgg ttacttcgcc
     7561 tacgccgcca gccattatca aactcaccaa taagcgccac ggcgaaggaa ttacgcggat
     7621 gtatgatttt gtgattatcg gcggcggcat tatcggcatg tcgaccgcca tgcaacttat
     7681 tgatgtctac ccggatgcgc gcatcgcgtt gctggaaaaa gagtccgcgc cagcctgcca
     7741 ccagaccggg cataacagcg gcgtgatcca tgccggggtg tactacacgc ccggcagcct
     7801 caaagcgcgg ttttgtctgg cgggcaatca ggcgaccaaa accttttgcg atcaaaacaa
     7861 catccgctac gacacctgcg gcaaaatgtt ggtcgccacc tcggagctgg aaatggcgcg
     7921 gatgcgcgcg ctatgggagc ggacggcggc caacggctta gagcgcgagt ggttaaacgc
     7981 ggcggagctg cgtgaacgcg aacccaatat cattggcctg ggcgggattt ttgtcccttc
     8041 cagcgggatt gtcagctatc gcgatgtcgc gacggccatg gcgaaccgct ttcaggccaa
     8101 aggcggcgag atcatctacc atgccgaggt cagcgcgcta acagaacatg ccgctggcgt
     8161 tatcattcgc acttcgcaag gccgagaaat cgaaaccgct acgcttatcg gctgtgcagg
     8221 gctgatggcg gatcggctgg tcaaaatgct gggcgtggag cccggtttta ttatctgccc
     8281 tttccgcggc gagtactttc gtctggcccc gcgacacaac cggatcgtta accatttgat
     8341 ctacccgatc cccgatccgg caatgccgtt tctcggcgtc caccttaccc gcatgatcga
     8401 cggcagcgtc acggtcgggc cgaatgcggt gctggcgctt aaacgcgaag gctaccgtaa
     8461 gcgcgacgtt tccttcaccg acaccctgga gattttccgc tccgccggca ttcgccgcgt
     8521 actgcaaaac catctgcttt ccggactggg cgagatgaaa aactcgctgt gcaaaagcgg
     8581 ctatttgcgg cgagtacaaa agtattgccc cagcctgacc gtcaacgatc tccagccctg
     8641 gccggcaggc gtgcgggcgc aggcggtttc gccggacggc aaactgattg atgattttct
     8701 gtttgtcacg acgccgcgtt ccattcacac ctgtaacgca ccctccccgg cggcgacatc
     8761 agcgatacct atcggcgcgc atatcgtcag taaagttcag gcgctacgcg caagccagag
     8821 caaccccgga cgtacgctgc gtgcggcacg cagcgtggac gcattacacg ccgcatttac
     8881 ccgttaaccc ttcagacagg aagcaattat gcaacttaac gactctaccc tgttccgcca
     8941 gcaggccttt atcgatggcg actggcgcga cgcgcgcggc ggcgatgtca tccccgtgag
     9001 caaccccgcc aacgggaaac cgcttggcaa tgtgcccaaa atgggggcgg aagagacgcg
     9061 cgacgccatc aacgccgcca atcgcgccct gcccgcctgg cgcgcgctca ccgccaaaga
     9121 gcgagccaat atcctgcgtc gctggttcaa tctgatgatg gaacatcagg acgatttggc
     9181 gcgtctgatg acgctggaac agggcaaacc gctggcggaa gcgaaaggcg aaattagcta
     9241 cgccgcctcg tttattgaat ggttcgccga agaggggaag cgtatctatg gcgacacgat
     9301 tccaggtcat cagaccgata aacggctgct ggtgattaaa cagcccatcg gcgtcaccgc
     9361 cgcgattacc ccgtggaact ttccctcggc aatgatcacc cgtaaagccg gccccgcgct
     9421 ggccgcaggc tgcacaatgg tactcaaacc cgccagccag acgccgtttt ccgcgctggc
     9481 gctggcggaa ctggcccagc gcgccggaat tctcgcaggc gtatttaacg tcgttaccgg
     9541 ttcggcaggc gatatcggcg gcgagctgac cagcaacccg ctggtacgca aactgtcgtt
     9601 taccggctcg acggagattg gccgccagct aatggaacaa tgcgccaaag acattaaaaa
     9661 agtatcgctg gagttgggcg gcaatgcgcc gtttatcgtc tttgacgatg ccgatctgga
     9721 taaagccgtc gagggcgcgc tggcttcgaa gtttcgcaac gccgggcaga cctgtgtctg
     9781 cgccaataga ttgtatgttc aggacggcgt ttacgatcgt tttgcggaaa aactcaacca
     9841 ggcggtaaat aagctcgcgg tcggcgacgg cctgcaagcc gacgtcgcta tcgggccgct
     9901 gattgatgaa aaagccgtgg ctaaagtcca ggagcatatc gccgacgcgc tggaaaaagg
     9961 cgcccgcgta attacgggcg gtgaagcgca caaattaggc ggcaacttct ttcaaccgac
    10021 cattctggcg gatgttcctg ataacgcgaa agtcgccaaa gaagagacat tcgggccgct
    10081 cgcgcctctg ttccgcttca gcgacgaggc ggatgtcatc aggcaggcta acgataccga
    10141 gttcggcctg gcagcctatt tttatgcacg cgatttaagc cgcgttttcc gcgtcggcga
    10201 agcgctggaa tacggcatcg tcggtattaa taccggcatt atctccaacg aagtcgcgcc
    10261 tttcggcggt attaaggcct ccggattagg ccgtgaaggt tccaaatacg gcatcgaaga
    10321 ttatttagaa atcaaatata tgtgcatcgg cctttaacag gagagtcgct aatgaatacc
    10381 aataacactt taatgcagcg ctgtcataac gccgttcctc gcggcgtggg ccagattcac
    10441 ccgattttcg ccgagcgggc ggaaaattgt cgggtctggg atgtcgaagg ccgtgagtat
    10501 ctcgatttcg cgggcggcat tgccgtcctg aacaccggtc atttacatcc gggcattgtt
    10561 tcagcggtcg aagcgcagtt gaagaaattg tcgcatacct gttttcaggt gctggcctat
    10621 gaaccgtacc tggcgctgtg cgaacgcatg aaccagaagg taccgggcga tttcgccaaa
    10681 aaaacgttgc tggtcacgac cggttcagaa gcagttgaaa acgcggtgaa aatcgcccgc
    10741 gcggcgacaa aacgcagcgg cgctatcgcg tttagcggcg cttaccacgg tcgtacccac
    10801 tacacgctct ctctgaccgg gaaagtacac ccgtactctg cgggtatggg attgatgcca
    10861 ggccatgtct accgcgcgct ttatccttgc ccgctacaca acatcagcga cgacgacgcg
    10921 atcgccagca ttgaacgcat ctttaaaaat gatgccgcgc cggaagatat cgccgccatt
    10981 attattgagc cggtacaggg cgaaggcgga ttttacgccg cctctcccgc gtttatgcag
    11041 cgactgcgcg cgctatgcga ccaacacggc attatgttga ttgccgacga agtgcaaagc
    11101 ggcgcgggcc ggaccggtac gctgttcgcc atggaacaga tgggcgttgc ggcagatatt
    11161 accacgtttg cgaaatcgat cgccggcggc tttccgctgg caggcgttac cggccgggca
    11221 gacgtgatgg acgctatcgc gccgggcggt ctgggcggca cctatgccgg aaacccgatt
    11281 gcctgcgtcg ccgcgctggc ggtactggac attttcgagc aggaaaatct actgcaaaag
    11341 gcgaatacgc ttggcaaaac gctgcgcgat ggcctgatgg agatagcgga aacgcaccgt
    11401 gagattggcg acgtgcgcgg actgggcgcc atgatcgcca ttgagttgtt cgaaaatggc
    11461 gaccccggca aaccgaacgc gactctgacc gccgacattg tggcccgcgc ccgcgagaaa
    11521 gggttaattc tgctctcctg cggtccttac tacaacatct tgcgcatcct cgttccactc
    11581 actattgagg cctcgcagat tcggcaaggc ctggagatta tcgcccagtg ctttgatgag
    11641 gcgaaacaag cgtaatgtcc aataagcagc gtcggatggc gacgtaactg tcttatccgg
    11701 cctacaaaaa ccgtttcgat tgtaggccga ataagccagg caccatccgg taaacgagcg
    11761 caataacaat aaagaggttt taggatgggg caattgtcag aatcacatgc attagggggc
    11821 gggctgaaat cacgccacgt caccatgtta tcgatcgccg gcgtcatcgg cgccagcctg
    11881 tttgtcggtt ccagcgtggc gattgcggag gccggccctg cggtactgct ggcctatctg
    11941 ttcgcaggac ttttagtcgt catgattatg cgaatgctgg ctgaaatggc cgtcgccaca
    12001 ccggataccg gttctttttc cacctatgcg gataaagcga tcggcccctg ggccgggtat
    12061 accatcggct ggttatactg gtggttttgg gtgctggtta ttccgctgga ggccaatatt
    12121 gccgccatta ttctgaattc atggataccg ggtattccgg tgtggctatt ttcattagtg
    12181 attacgcttg ccttaaccgg aagcaattta ttgagcgtca aaaattacgg tgaattcgaa
    12241 ttctggctgg cgctatctaa agtaattgcc attctggcgt ttatcgcgct gggcgcggcg
    12301 gcgattagcg gtttttatcc gtatgccgag gtaagcggta tttcccggct ctgggatcac
    12361 ggcggtttta tgcctaacgg cttcggtgcg gtgttaagcg ccatgttgat caccatgttc
    12421 tcttttatgg gcgcggaaat cgtcactatt gctgccgcgg aatccgatac gccggataaa
    12481 catatcgtac gcgccaccaa ttctgttatc tggcgaattt ccatctttta cctgtgttcc
    12541 atttttgtgg tagtggcgct gatcccgtgg aatatgccgg gtctgaaaag cgtaggttcg
    12601 taccgttcgg tactggagct gcttcatatt ccgcacgcaa aattcattat ggactgcgtg
    12661 attttattgt cggtgaccag ttgtctgaac tccgcattat ataccgcctc ccggatgctc
    12721 tattccctta gccgccgcgg cgatgcgcct gcgataatgg gaaaaactaa ccgtagcaaa
    12781 acgccctggg tggcggttct cctctctacc ggcgcggcct ttttaaccgt tatcgtcaat
    12841 tattacgccc cggcaaaagt gtttaaattt cttatcgaca gttccggcgc catcgcgctg
    12901 ctggtctatc tggtgattgc gatttcgcaa ttgcggatgc gtaaaattct gctggcgcag
    12961 ggcggagaaa ttaagttgaa aatgtggctt tatccgtggc tcacctggct ggttatcggc
    13021 tttatctgct ttgttctggt ggtgatgcta tttcgaccgg cacagcaact agaagtcatt
    13081 tcaacggggc tgttagggct gggcataata ggtactgtcc ccattatgtc tcgctggaaa
    13141 aaactgataa ggtggcaaaa agcccccctg caaaacctac gttagttatt cccggcgtca
    13201 gccgggaagc ttctcaggag taaaagatga ccgccctttc ccaaccgacg gccatagatg
    13261 gctatcgctg gcttaaaaat gacattattc gcggcactta tcagccggat gagaaactgc
    13321 ggatgagttt attaaccgcc cgctatgcgc tcggcgtagg gccgctgcgc gaggcgctgt
    13381 cacaactggt ggcggaacgg ctggtcaccg tggtgaatca aaaaggctat cgcgtggcat
    13441 ccatgtcaga ggcggaactc ctcgatattt ttgacgcgcg cgccaatatg gaagcgatgc
    13501 tggtgcgcct ggcgattgaa cgcggcgatg atgcgtggga ggcggagatc ctggcgcgag
    13561 cgcatatgct cagtaaactg gaagccagcg atgccagtga acatatgctc gatgaatggg
    13621 atcagcgcca ccaggcgttt cattccgcca ttgtcgccgg gtgcggctcc cactatctgc
    13681 tacagatgcg cgaacgctta tttgacctgg cggcccgcta ccgctttatt tggttacgtg
    13741 aaaccgttct gtccgtcgag atgctggaag ataaacatat ccagcatcac acgctaaccg
    13801 aagcgatact ggcgcgcgag gcggcacgcg ccagcgaatt aatgcgtcag catttgctga
    13861 cgccgattcc cattattcgc caggcgatgg caggaaaaat gtagccaggc acggcctgat
    13921 agccattatt cttcaggaat acgcaacact tgtcccggat atattttttc cgggcttttc
    13981 agcatcggtt tatttgcctc gaagatttta ttatacagat tggcgttacc atacacttgc
    14041 tttgaaatag cgctcagggt gtcgcctgat tttacggtat aaaactgact ttcagccgct
    14101 ggcgtcgtgg ttttaacctg atcgtcaacg ctgctaatcc cggcgatatt ccccacggca
    14161 accagaattt tttcttttgc ctcctgactc agcccatcac ccgtcactgt cgcttttcca
    14221 tcagcaattt gcacattcac tttgtcagcg tcgggtattc ccgttttatt taaatgttcc
    14281 tagacttttt tcgcctgatc gtccttatca tgattagcgg ttaccgcgtc ccagagtttt
    14341 tcacctgcat cttttacaaa attgaaaagt cccatattca cctcgcttgt caaaaataca
    14401 cacaaagaaa agtgtagcag agggaatgag gttatcctga taagcggcgc ttatgcgccg
    14461 ccggtggccg gtaattaatg acgcatctga acccaaaatg catggataag ccccggaata
    14521 tatccgagta atgtcagcag gatattaagg ataaatgccc aaccgaaccc ttttcctaaa
    14581 agtacgccga gcggaggcaa aataatcgta aatacaatt
//
LOCUS       DAJVBX010000112        14618 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.112, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000112 DAJVBX010000000
VERSION     DAJVBX010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 14618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14618
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.112"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(26..484)
                     /locus_tag="OPV72_002830"
     CDS             complement(26..484)
                     /locus_tag="OPV72_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF986 domain-containing protein"
                     /protein_id="HCR9915076.1"
                     /translation="MTITDLVLILFIAALLAYALYDQFIMPRRNGPTLLSIALLRRGR
                     IDSVIFVGLVAILIYNNVTSHGAQMTTWLLSALALMGFYIFWIRTPRIIFKQRGFFFA
                     NVWIEYNRIKEMNLSEDGVLVMQLEQRRLLIRVRNIDDLEKIYKLLIENQ"
     gene            complement(543..1394)
                     /locus_tag="OPV72_002831"
     CDS             complement(543..1394)
                     /locus_tag="OPV72_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IID"
                     /protein_id="HCR9915077.1"
                     /translation="MVDMTKTTTEKKLTPSDIRGVFLRSNLFQGSWNFERMQALGFCF
                     SMVPAIRRLYPENNDARKQAIKRHLEFFNTHPYVAAPVLGVTLAMEEKRANGAEIDDG
                     AINGIKVGLMGPLAGVGDPIFWGTVRPVFAALGAGIAMSGSLLGPLLFFILFNLVRLA
                     TRYYGVAYGYRKGVDIVKDMGGGFLQKLTEGASILGLFVMGALVNKWTHVNIPLVVST
                     ITGQDGQTRVTTVQTILDQLMPGLVPLLLTFACMWLLRKKVNPLWIIVGFFVIGIAGY
                     SVGLLGQ"
     gene            complement(1407..2207)
                     /gene="manY"
                     /locus_tag="OPV72_002832"
     CDS             complement(1407..2207)
                     /gene="manY"
                     /locus_tag="OPV72_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002910918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIC"
                     /protein_id="HCR9915078.1"
                     /translation="MEITTLQIVLVFIVACIAGMESVLDEFQFHRPLIACTLIGAVLG
                     DMKTGIIIGGTLEMIALGWMNIGAAVAPDAALASIISTVLVIAGHQSIGAGIALAIPL
                     AAAGQVLTIIVRTITVAFQHAADKAAENGNLTALSWLHVSSLFLQAMRIAIPAVIVAI
                     SVGTSEVQGMLNAIPEVVTGGLNIAGGMIVVVGYAMVINMMRAGYLMPFFYLGFVTAA
                     FTNFNLVALGVIGAVMAILYIQLSPKYNRVAGAPAAAAGNNDLDNELD"
     gene            complement(2260..3228)
                     /gene="manX"
                     /locus_tag="OPV72_002833"
     CDS             complement(2260..3228)
                     /gene="manX"
                     /locus_tag="OPV72_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HCR9915079.1"
                     /translation="MTIAIVIGTHGWAAEQLLKTAEMLLGEQENVGWIDFVPGENAET
                     LIEKYNAQLAKLDTSKGVLFLVDTWGGSPFNAASRIVVDKERYEVIAGVNIPMLVETF
                     MARDDDPSFDELVALAVETGREGVKALKAKPVEKAAPAPVAAAPKAATPAKPMGPNDY
                     MVIGLARIDDRLIHGQVATRWTKETNVSRIIVVSDEVAADTVRKTLLTQVAPPGVTAH
                     VVDVAKMIRVYNNPKYAGERVMLLFTNPTDVERIVEGGVKVTSVNIGGMAYRQGKTQV
                     NNAVSVDEKDIEAFKKLNERGIELEVRKVSTDPKLKMMDLIAKVAK"
     gene            3701..5260
                     /gene="yoaE"
                     /locus_tag="OPV72_002834"
     CDS             3701..5260
                     /gene="yoaE"
                     /locus_tag="OPV72_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460784.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CNNM family cation transport protein YoaE"
                     /protein_id="HCR9915080.1"
                     /translation="MELLMDPSIWVGLLTLVVLEIVLGIDNLVFIAILADKLPPKQRD
                     KARLIGLSLALIMRLALLSIISWLVTLTKSLFTVWDFTFSGRDLIMLLGGIFLLFKAT
                     TELHERLENREHDTGHGKGYASFWVVVTQIVILDAVFSLDAVITAVGMVNHLPVMMAA
                     VVIAMAVMLLASKPLTRFVNQHPTVVVLCLSFLLMIGLSLVAEGFGFHIPKGYLYAAI
                     GFSIVIEVFNQIARRNFIRHQSTLPLRARTADAILRLMGGKRQASMQHETDSPAAISV
                     SEGAFAEEERYMINGVLTLASRSLRGIMTPRGEISWVDANLSVAEIRQQLLSSPHSLF
                     PVCRGELDEIIGIVRAKELLVALEEGADVAAIAASSPAIVVPETLDPINLLGVLRRAR
                     GSFVIVTNEFGVVQGLVTPLDVLEAIAGEFPDADETPEIVADAEGWIVKGGTDLHALQ
                     QALEVDHLVNEEGDIATVAGLVIAANGHIPRVGDVIDVPPLRITIVEANDYRVDLVRI
                     VKEQPAHDEEE"
     gene            complement(5282..6883)
                     /locus_tag="OPV72_002835"
     CDS             complement(5282..6883)
                     /locus_tag="OPV72_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001192512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HCR9915081.1"
                     /translation="MQTAQRIINHYRRNRFIVCTICALVTLILTLNIRFISERNLNHH
                     RTVAFANHAVDALDNVLHPLLVGRNILLPLLELPCATAHLPLRKQAARLQTIRSIGLV
                     KEGILYCSSIFGARNTPIRQLQPDLPAAGDLLLLSTDQSLLKGSPILIQWYPASADGQ
                     DGVMEIVNIDLLATMLLEPQQPQITSASLTVGKRHLLYGRGVVDTLPELKKDEERYQL
                     SSRHFPFTISVSGPSAGVLAFKHLPTQLPLAVLLSLLIGYIAWLATASRMSFSWEINL
                     ALAEREFELFCQPLLNARTQQCTGVEILLRWNNPRQGWISPDVFIPITEEHNLIAPLT
                     RYVIAETIRQRHYFPINHQFHIGINVAASHFRHGVLLKDLNQYWFSAEPVQQLVLELT
                     ERDALLDVDYRLMRELHRKGVKLAIDDFGTGNSSLSWLEKLRPDILKIDKFFTAVIGT
                     DAVNSTVTDIIIALGQRLNIELVAEGVENQTQAQHLRQHGVQMLQGYLYAKPMPISEF
                     PQWLAGSAPPPARHNGQIMSAMPHL"
     gene            complement(7021..8385)
                     /gene="sdaA"
                     /locus_tag="OPV72_002836"
     CDS             complement(7021..8385)
                     /gene="sdaA"
                     /locus_tag="OPV72_002836"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HCR9915082.1"
                     /translation="MISLFDMFKVGIGPSSSHTVGPMKAGKQFVDDLVEKGLLDNVTR
                     VAVDVYGSLSLTGKGHHTDIAIIMGLAGNEPATVDIDSIPGFIRDVETRERLLLAQGR
                     HEVDFPKDDGMRFHNGNLPLHENGMQIHAWHDDTVIYSKTYYSIGGGFIVDEAHFGQE
                     ATNEVTVPYPFKSAKEMLEYCNSTGLSLSGMVMQNELALHSKKEIEEYFGHVWQTMQA
                     CIDRGMNTEGVLPGPLRVPRRASALRRMLVSSDKLSSDPMNVIDWVNMFALAVNEENA
                     AGGRVVTAPTNGACGIVPAVLAYYDHFIESVSPDIYTRYFLAAGAIGALYKMNASISG
                     AEVGCQGEVGVACSMAAAGLAELLGASPEQVCVAAEIGMEHNLGLTCDPVAGQVQVPC
                     IERNAIASVKAINAARMAMRRTSAPRVSLDKVIETMYETGKDMNAKYRETSRGGLAIK
                     VQCD"
     gene            complement(8649..9227)
                     /locus_tag="OPV72_002837"
     CDS             complement(8649..9227)
                     /locus_tag="OPV72_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HCR9915083.1"
                     /translation="MDTSRLTLDHFLSRFQLLRPQMTHETLNQRQAAVLIPVVRRPQP
                     GLLLTQRAIHLRKHAGQVAFPGGAVDSTDASLIAAALREAQEEVAIPPQAVEVIGVLP
                     PVDSVTGFQVTPVVGIIPPNLPWRASEDEVSAVFEMPLAQALQLGRYHPLDVYRRGNS
                     HRVWLSWYEHYFVWGMTANILRELALQIGVKP"
     gene            complement(9231..10595)
                     /gene="pabB"
                     /locus_tag="OPV72_002838"
     CDS             complement(9231..10595)
                     /gene="pabB"
                     /locus_tag="OPV72_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component 1"
                     /protein_id="HCR9915084.1"
                     /translation="MMKTLSPTVITLPWRPDAAEHYFAPVNHLPWAMLLHSGDAIHPY
                     NRFDILVADPVTTLTTRAQETTVCTARTTTVTLDDPLHVLQTQLEALPFHPQPDPDLP
                     FQGGALGLFGYDLGRRFEILPDTAARDIALPDMAIGLYDWALIVDHHKQVVSLISYHD
                     ADARYRWLTGQRAPTRTPFRLTSAWQSNMTRCEYGEKFRQVQAWLHSGDCYQVNLSQR
                     FQASYEGDEWQAFERLNRANRAPFSAFLRLHDGAILSLSPERFIQLENGHIQTRPIKG
                     TLPRLNDPQADRQQAQKLANSMKDRAENLMIVDLMRNDIGRVAVPGSVKVPELFVVEP
                     FPAVHHLVSTITARLPDSLHATDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWC
                     GSIGYLSFCGKMDTSITIRTVTATQGQLYCSAGGGIVADSNEEAEYQETFDKVNRILH
                     PLEN"
     gene            10676..10855
                     /locus_tag="OPV72_002839"
     CDS             10676..10855
                     /locus_tag="OPV72_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoaH family protein"
                     /protein_id="HCR9915085.1"
                     /translation="MFAGLPSLSHEQQQKAVERIQELMSQGMSSGEAIAQVAGELRAN
                     HTGERIVARFEDEDE"
     gene            complement(10861..11205)
                     /locus_tag="OPV72_002840"
     CDS             complement(10861..11205)
                     /locus_tag="OPV72_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HCR9915086.1"
                     /translation="MSIVRIDAEDRWSDVVIYNNTLWYIGVPENLDADAFEQTANTLA
                     QIDAVLEKQGSSKSRILDATIFLSDKADFAAMNKAWDAWVVAGHAPVRCTVQAGLMNP
                     KYKVEIKIVAAV"
     gene            11337..13247
                     /locus_tag="OPV72_002841"
     CDS             11337..13247
                     /locus_tag="OPV72_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HCR9915087.1"
                     /translation="MTDDFAADGQLAKAITGFKPREPQRQMAVAVTQAIENAQPLVVE
                     AGTGTGKTYAYLAPALRAGKKVIISTGSKALQDQLYSRDLPTVAKALAFTGKTALLKG
                     RSNYLCLERLEQQALAGGDLPVQTLSDVILLRSWSNQTRDGDISTCVSVAEDSQAWPL
                     VTSTNDNCLGSDCPLYKECFVVKARKKAMDADVVIVNHHLFLADMVVKESGFGELIPQ
                     AEVMIFDEAHQLPDIASQYFGQSLSSRQLLDLAKDITIAYRTELKDTQQLQKCADRLA
                     QSAQDFRLQLGEPGYRGNLRELLADSRIQRAFLLLDDTLELCYDVAKLSLGRSALLDA
                     AFERATLYRSRLKRLKEINQPGYSYWYECTSRHFTLALTPLTVADKFKEVMEQKPGSW
                     IFTSATLSVNDDLHHFTARLGIEQAESMLLPSPFDYTRQALLCVPRNLPQTNQPGAAR
                     QLAAMLRPIIEANNGRCFMLCTSHAMMRDLAEQFRATMTLPVLLQGETSKGQLLQQFV
                     SAGNALLVATSSFWEGVDVRGDTLSLVIIDKLPFTSPDDPLLKARMEDCRLRGGDPFD
                     EVQLPDAVITLKQGVGRLIRDADDRGVLVICDNRLVMRPYGATFLASLPPAPRTRDIA
                     RAVRFLAIPSAE"
     gene            13305..14000
                     /gene="tsaB"
                     /locus_tag="OPV72_002842"
     CDS             13305..14000
                     /gene="tsaB"
                     /locus_tag="OPV72_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HCR9915088.1"
                     /translation="MRILAIDTATEACSVALWNNGTINAHFELCPREHTQRILPMVQE
                     ILAASGASLNEIDALAFGRGPGSFTGVRIGIGIAQGLALGANLPMIGVSTLATMAQGA
                     WRKTGATRVLAAIDARMGEVYWAEYQRDAQGVWQGEETEAVLKPERVGERLKQLSGEW
                     ATVGTGWSAWPDLAKECGLTLHDGEVSLPAAEDMLPIASQKLAAGETVAVEHAEPVYL
                     RNEVAWKKLPGKE"
     gene            14071..>14618
                     /locus_tag="OPV72_002843"
     CDS             14071..>14618
                     /locus_tag="OPV72_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Slp family lipoprotein"
                     /protein_id="HCR9915089.1"
                     /translation="MAVQKRLIKGALACAFALMLSGCVTIPDAIKGSSPTPQQDLVRV
                     MNAPQLYIGQEARFGGKVVAVQNQQGKTRLEIATVPLDSGARPVLGEASRGRIFADVN
                     GFLDPVDFRGQLVTVVGPITGTVDGKIGNTPYKFMLMQATGYKRWHLVQQVVMPPQPI
                     DPWFYGGRAWPYGYGGWGWYNPG"
BASE COUNT         3385 a         3852 c         4058 g         3323 t
ORIGIN      
        1 aacatagttg aggctatatc ttaagctatt gattttcaat aagaagttta tatatttttt
       61 ccagatcgtc gatattgcgt acacggataa gcaagcgtcg ttgttctaat tgcatcacca
      121 gtacgccgtc ctccgataaa ttcatctctt taatacggtt atattctatc cagacattgg
      181 caaagaaaaa gccacgttgt ttaaagatga tccgtggcgt gcggatccag aatatataaa
      241 accccattaa cgccagcgcg cttaataacc atgtggtcat ctgcgctccg tggctggtta
      301 cgttgttata aataaggatg gcgaccagcc caacgaagat aacgctgtct atgcgaccgc
      361 ggcggagcag ggctatagaa agcagagtgg ggccattgcg acggggcatg atgaactgat
      421 cgtagagagc gtaagccaat aatgcggcaa taaagagaat cagcaccagg tccgtgatag
      481 tcatttatcc tccagagaaa taaaaaaacg gggccgtttg gccccggtag tgtacaacag
      541 ccttactggc ccagcagtcc tacggagtag ccggcgatac caatgacgaa gaagcccacg
      601 ataatccaca gcgggttaac tttcttacgc agcagccaca tacaggcaaa ggtcaacagt
      661 agcggaacca gacccggcat cagctggtcg agaatggttt gcacggtggt aacgcgtgtc
      721 tgaccatcct gaccggtgat ggtggagacc accagcggga tattcacatg cgtccacttg
      781 ttaaccaatg cccccatgac aaacaggccg aggattgacg ccccctcagt cagtttttgc
      841 aggaagccgc cgcccatatc tttaacgata tcgacgcctt tgcggtagcc ataagccacg
      901 ccataataac gggtcgccag acgcaccagg ttaaacagga tgaaaaacag cagcggacca
      961 agcaggctgc cgctcattgc aatacctgcg cccagcgccg cgaatactgg acggacggta
     1021 ccccagaaga tagggtcgcc gacgcctgcc agcggtccca tcagaccgac tttgataccg
     1081 ttgatagcac catcgtcaat ctctgcgccg ttcgcacgct tttcttccat tgccagcgtt
     1141 acgcccagta ccggcgccgc aacgtaagga tgagtgttaa agaactccag gtgacgctta
     1201 atcgcctgtt tacgcgcgtc attattctcc ggatacaggc gacgaatcgc cggcaccata
     1261 gagaagcaga agcccagcgc ttgcatacgt tcgaagttcc atgacccctg gaacaggtta
     1321 gaacgaagaa atacgccgcg aatatcgctc ggagtgagtt ttttctcggt ggtagtttta
     1381 gtcatatcaa ccatttcgct cacctgttag tccagttcgt tatcgagatc gttattgcca
     1441 gcagccgctg caggcgcgcc cgctacacgg ttgtatttcg ggctcagctg gatgtaaaga
     1501 atagccatca ctgcgccgat gacacccagt gcgaccaggt tgaagtttgt gaaagccgcg
     1561 gtgacgaaac cgaggtagaa gaacggcatc aggtagcctg cgcgcatcat gttgataacc
     1621 atcgcataac caaccacgac gatcatgccg ccggcgatgt tcagaccgcc tgtgacgact
     1681 tcaggaatcg cattcagcat tccctgtact tcgctggtgc ctacggagat ggcaacgata
     1741 accgccggga tggcgatacg cattgcctgc aggaacagag aagaaacgtg cagccaggag
     1801 agcgccgtca ggttgccgtt ttcagccgcc ttgtccgccg cgtgctggaa tgccacggtg
     1861 atggtacgaa cgataatggt cagtacctgg cctgccgccg ccagcggaat cgccagcgcg
     1921 ataccggcgc caatgctttg atgcccagcg atgaccagaa cggtagagat gatggacgcc
     1981 agtgcggcat caggcgcaac ggcagcaccg atgttcatcc agcccagagc gatcatttcc
     2041 agagtaccgc cgatgataat accggttttc atgtccccca gaacggcgcc gattaaggta
     2101 caggcgatca gcggacggtg gaactgaaat tcatcaagta ccgactccat acccgcgata
     2161 catgcgacga tgaacaccag cacaatctga agagtggtaa tctccattgt acttctccta
     2221 ttgctatctt aagtgtgaaa gctaattaaa tgccggcggt tatttcgcca ctttggcaat
     2281 taaatccatc attttcagtt tcggatcggt ggaaacttta cgcacctcaa gctcgatgcc
     2341 gcgctcgttg agctttttaa aggcttcgat atccttttca tcgacggaaa cggcgttgtt
     2401 cacctgcgtt ttaccttgac gataggccat accgccaatg ttcacggagg tgactttcac
     2461 gccgccctca acgatgcgct cgacgtcggt aggattggta aacagaagca tcacgcgttc
     2521 gccggcgtat ttcgggttat tgtagacgcg aatcatcttc gcgacgtcaa ccacatgcgc
     2581 cgtaacgccc ggcggcgcaa cttgcgtcag cagcgtttta cgtacggtat ccgccgcgac
     2641 ttcatcgctc acaacaataa tacggctgac attggtctct ttggtccagc gggtagcgac
     2701 ctgaccgtga atgaggcggt catcaatacg ggcaagcccg ataaccatat aatcattcgg
     2761 gcccatcggt tttgccggcg tggccgcttt tggcgcggcg gcgaccggcg ctggcgcggc
     2821 tttttctacc ggtttcgctt tcagcgcttt tacgccttca cgaccggttt ctaccgccag
     2881 tgcgaccagc tcgtcaaagc tcggatcgtc gtcacgagcc ataaacgttt cgaccagcat
     2941 cgggatgttg acgccggcaa taacttcata gcgctcttta tcgacgacaa tgcggctggc
     3001 agcattaaac ggactgcctc cccatgtatc aacgagaaat agcacgcctt tactggtatc
     3061 gagtttagcc aactgagcgt tgtacttttc gatcagcgtt tcggcatttt cgcctggaac
     3121 gaaatcgatc cagccgacgt tttcctgctc gcctaacagc atttcggctg ttttaagtaa
     3181 ctgctctgca gcccaaccat gtgtgcctat aacaatagca atggtcactt gctacctcct
     3241 ttattattgt caacacatca acttgacaga tgtatttttt gaatcgccgt ccgcaagcga
     3301 atcgattcag atgagggtta caacgaaaaa cgcatgattt tcgtgaatta ttttagatat
     3361 cgaaaaaaat attttgtgtg atggagatct gtaattttgt tttcgataat gagaaatttc
     3421 gaagtgtaaa atatcctggt tacatctctt tgcaaaggaa ggtaaatctt tgccaaaaac
     3481 cagttgtctc tgttatgttt agcttccgtt taattagaat ggggtatagg gcagcagccc
     3541 gttgtatgga tcgtcaccga cgtcatttca ctctttggcc gttttgcgcc tgtcaatctg
     3601 gcatatcttg ccatagcctt actttgttta ttgcgttacc gcctgcatcc tttgagatgt
     3661 tgtgggcgcc gtttagtcat tccttaagca ggagcttgtc atggaattat taatggatcc
     3721 ctcaatttgg gtgggtttac tcacgctcgt cgtcctggaa attgtcctag gtatcgataa
     3781 cctggtcttt atcgcgatcc tcgccgataa attgccgcca aagcagcgtg acaaagcgcg
     3841 tcttatcggg ctctcgctgg cgctgattat gcgtctggcg ctgctgtcca ttatttcgtg
     3901 gctggtgacc ttaacaaagt cgctctttac tgtctgggat tttaccttct ccggccgcga
     3961 tttaattatg ctgctgggcg gtatattcct gctgtttaaa gcgaccaccg agctgcatga
     4021 acgtctggaa aaccgcgagc atgacaccgg acacggtaaa ggctatgcga gcttctgggt
     4081 ggtagtcacg cagattgtca tcctggatgc ggtcttctcg ctggacgccg tgattacggc
     4141 ggtaggtatg gtaaaccatc tgccggttat gatggcggcg gtggtgattg cgatggcggt
     4201 gatgctactg gcgtcaaaac cgctgacccg ttttgtcaac cagcatccga cggtggtggt
     4261 gctctgtctg agtttcctgc tgatgatcgg cttgagcctg gtggcggaag gatttggttt
     4321 ccatattccg aaaggctacc tgtacgcggc aattggtttc tcgatcgtta tcgaggtgtt
     4381 taaccagatt gcgcgccgca actttattcg tcatcagtcc acgttgccgc tgcgcgcgcg
     4441 tactgcggac gctatcctgc gtctgatggg cggtaaacgt caggcgagta tgcaacatga
     4501 gacggatagc ccggccgcga tatcggtgtc ggaaggcgcc ttcgccgaag aagaacgcta
     4561 catgattaac ggcgtactga ctctggcgtc gcgctccctg cgcggcatta tgacgccgcg
     4621 aggcgaaatt agttgggtgg atgcgaatct cagcgtagct gaaatccgtc agcagttact
     4681 ctcttctccg catagcctgt tcccggtatg tcggggcgag ctggatgaaa ttatcggtat
     4741 cgttcgggcg aaagagttgc tggtggcgct ggaagagggc gcggacgttg cggctatcgc
     4801 cgcctcttcc ccggcgatag tggtgccgga aacgcttgat cctatcaatc tgttaggcgt
     4861 tttgcgtcgc gcgcgcggca gtttcgttat cgtcactaac gagttcggcg tggtgcaggg
     4921 gctggttacg ccgctggatg tgctggaagc gattgccggt gagttcccgg atgccgatga
     4981 aacgccggaa atcgttgccg atgccgaggg ctggatagtg aagggcggca ccgatcttca
     5041 tgcgttacag caggcgctgg aagttgacca tctggtgaac gaagagggtg atattgcgac
     5101 ggtcgcgggg ttagtgatcg ccgctaatgg ccatattcct cgtgtaggcg atgtcattga
     5161 tgttccgccc ctgcggatca ccattgtcga ggccaacgac taccgtgtcg atctggttcg
     5221 aattgttaaa gaacagcctg cccacgacga agaggaataa cgtcacacgc aggaatcaag
     5281 tctatagatg cggcatcgcg gacataatct gtccgttatg ccgggcgggc ggcggcgcgc
     5341 tgcccgccag ccactgtgga aattcgctaa tgggcatcgg cttcgcatag agatagccct
     5401 gtaacatttg cacgccatgc tggcgcaaat gctgtgcctg cgtctggttt tcgacccctt
     5461 ccgcaaccag ttcaatattc agtctttgcc ccagcgcgat aataatatcg gtcaccgttg
     5521 aattgaccgc atcggtaccg atgacggcgg tgaagaattt atcgattttc aaaatatccg
     5581 gacgcagttt ttccagccag gagagcgagc tgtttcctgt gccaaaatca tcgatggcta
     5641 acttcacgcc tttacgatgc agctcgcgca tcaggcggta atcaacgtca agcaacgcgt
     5701 cgcgttccgt gagctccagc accagttgct gaacaggttc cgcactaaac cagtactgat
     5761 taagatcctt gagaagcacg ccgtgtcgga aatggcttgc cgccacattg atgccgatat
     5821 gaaactgatg gttgatgggg aagtagtgcc gctgccgaat ggtttccgca atcacatagc
     5881 gggtcagcgg cgctatcagg ttatgctcct cggtgatagg aataaaaaca tccggtgaga
     5941 tccagccctg gcgcgggtta ttccagcgta acaggatctc aacgccggta cactgctgcg
     6001 tgcgggcatt aagcaacggc tgacaaaata gctcaaactc ccgttcggca agggccagat
     6061 taatttccca ggaaaagctc attctgctgg cggttgccag ccaggcgata taaccgatca
     6121 acaggctaag caatacggcc agcggtaact gcgtcgggag atgtttgaac gccagtacgc
     6181 ctgccgacgg cccgctgacg ctgatagtaa aagggaaatg ccgcgatgaa agctggtaac
     6241 gctcttcatc tttttttaat tccggaagag tatcgaccac gccccgacca tataacaggt
     6301 gccgtttgcc gaccgtcagg ctggcgctgg taatttgcgg ctgctgcggc tcaagtagca
     6361 tagtcgccag caagtcaata ttcacaattt ccatcacgcc atcctgtcca tcggcagagg
     6421 cgggatacca ctgaatgagg atcgggcttc ccttgagtaa cgattggtcc gtggaaagta
     6481 gcagcagatc gccagctgcg ggaagatcgg gctgaagctg gcgtatggga gtattacggg
     6541 cgccaaaaat gcttgagcag tagagaattc cctcttttac cagcccgata gaacgaatgg
     6601 tttgcaggcg ggcggcttgc ttacgcaacg gcagatgcgc ggtcgcgcac ggaagctcaa
     6661 gtaagggtag cagtatgttt cgtccgacca ggagaggatg cagcacatta tccagcgcat
     6721 caacggcatg attcgcgaat gcaaccgtgc gatggtgatt taagttccgc tccgaaataa
     6781 atcggatgtt cagcgtaaga atgagcgtga ccagtgcaca aatcgtgcaa acaatgaaac
     6841 gattacggcg ataatgattg atgatccgtt gtgctgtttg catgcgggcc gcccaataag
     6901 cgttggcgac aaaagccaac cgcgacacag caagtgtagt ggggaaacgt ggagtcgacg
     6961 aggaagagat aaaaatttcg cccatccgta gcagatgggc gaagggaggg gaaatggcgt
     7021 ttaatcacac tggactttaa tagccaaccc gccgcgcgac gtttcgcggt atttggcgtt
     7081 catgtctttt ccggtctcgt acatcgtttc gatgacttta tccagcgaga cgcgcggcgc
     7141 gctggttcga cgcatggcca tacgcgcagc gttgatcgct ttaaccgaag caatggcgtt
     7201 acgctcgata cacggcacct gcacctgacc ggcaaccggg tcgcaggtca gccccaggtt
     7261 atgctccatg ccgatttcag cggcaacgca aacctgttcc gggctggcgc ccaacagttc
     7321 agcaaggcct gccgccgcca tcgaacaggc gaccccgact tcgccctgac agccgacttc
     7381 cgcgccggaa atagacgcgt tcatcttata cagcgcgcca atagcgcctg ccgccaggaa
     7441 gtagcgggtg taaatatccg ggctgacaga ctcaataaaa tggtcgtagt aagccagtac
     7501 cgcaggaacg atgccgcacg cgccgttggt tggcgccgtc acgacgcgac cgcctgcggc
     7561 gttctcttcg ttcaccgcca gagcaaacat gttcacccag tcaatgacgt tcatcggatc
     7621 gctggaaagc ttatcgctgg aaaccagcat acgacgcagc gcagaggcgc gacgcggtac
     7681 gcgcagcggc cccggcagaa cgccttcggt attcataccg cgatcaatac aagcctgcat
     7741 ggtttgccag acgtgaccga aatactcttc aatctctttc ttgctatgca gcgccagttc
     7801 gttttgcatc accatgccgg agagtgaaag gccggtgctg ttgcaatact ccagcatttc
     7861 tttcgccgat ttaaacggat aaggtacagt aacctcattc gtcgcttcct ggccgaaatg
     7921 cgcttcatca acgataaagc cgccgccgat ggaatagtac gtcttgctat aaatgaccgt
     7981 gtcgtcatgc caggcgtgga tctgcatccc gttttcatgc agcggcaaat tgccgttgtg
     8041 aaaacgcatt ccgtcatctt tcgggaagtc gacttcgtga cgtccctggg ccagtaacag
     8101 acgctcgcgc gtttcgacgt cgcgaataaa accggggata ctatcaatat ccacggtagc
     8161 gggttcatta cccgccagac ccataataat ggcgatatcg gtatggtgac ctttccccgt
     8221 cagcgacagc gagccgtaga catcgacagc gacgcgggta acgttatcca gtaatccttt
     8281 ttcgactagg tcatcgacga actgtttacc ggccttcatc gggccaacag tgtgggaaga
     8341 ggagggacca atccctacct taaacatgtc gaataggcta atcacgataa tactcctgac
     8401 agggcaaccg gggcttccgg ttacgatgtt ataactgcgc atagtgtaag agggaacgct
     8461 ggcatcagct taactattca catgaattaa actaatgaat aaccgcgttt ttactaatat
     8521 tgcgacagta atctcaagtc gtgtcttgcg cgcgtaaagt taagtatata cacgttgccc
     8581 ttcaggctgc ctctttgggg gaggcgattg ttaccgcctt gaggcaacgt gaatggcgtt
     8641 gtgtacagtc agggctttac gccgatttgc agcgccagct cacgaagaat gtttgcggtc
     8701 atgccccaga cgaaataatg ctcataccag gagagccata cgcggtgcga attgccgcga
     8761 cggtaaacat caagcggatg atatcgaccc agttgcaacg cttgcgccag cggcatttca
     8821 aacaccgcag acacttcgtc ttcactggcg cgccagggga gatttggcgg aataatgccg
     8881 accaccgggg tgacctgaaa accggtcacg ctgtctaccg gcggtaaaac gccaatcact
     8941 tccacggctt gcggcgggat ggcgacttcc tcctgcgctt cgcgaagcgc tgcggcgata
     9001 agcgaagcat cggtactgtc cacggccccg ccgggaaagg cgacctgtcc ggcgtgtttg
     9061 cgcaaatgaa tagcccgctg ggtcaacagc agccccggct gggggcggcg aaccacaggg
     9121 atcagtacgg cggcctgacg ttgatttaac gtttcatgag tcatctgcgg gcgcaaaagc
     9181 tgaaagcgcg ataagaaatg atcgagcgtc agacggctgg tatccacgta ttagttctcc
     9241 agtgggtgca ggatacgatt aactttatca aaagtttcct gatattccgc ttcttcgttg
     9301 ctatcggcca cgataccgcc gccggctgag caatagagtt ggccctgcgt tgccgtgacg
     9361 gtgcggatag taatactggt atccatcttg ccgcagaaac tcagataacc gatgctaccg
     9421 caccaggcgt tgcgtcgctg cggctccagt tcgtcgataa tttccattgc ccgcacttta
     9481 ggcgcgccgg taatggagcc gccggggaaa gccgcgcgca gcagatcggt ggcatgaagc
     9541 gagtctggta aacgggcagt aatggtgcta accagatggt gaacggcagg aaatggttcg
     9601 acgacgaaca gttccggcac tttcaccgaa cctggtacgg cgacccggcc aatgtcgtta
     9661 cgcatcaaat cgacaatcat caaattttca gcgcgatctt tcattgaatt agccagtttc
     9721 tgcgcctgct gacgatccgc ctgcggatcg ttaagccgtg gaagcgtacc tttgatcggg
     9781 cgcgtctgaa tatgaccgtt ctccagttgg ataaaacgct cgggagaaag gctcaatatg
     9841 gcgccgtcat gtaaacgaag aaaggcgctg aacggggcgc gatttgcgcg gttaaggcgt
     9901 tcgaaagcct gccattcatc accctcgtag ctcgcctgaa aacgctggga aagattgacc
     9961 tgatagcagt ccccgctgtg cagccaggcc tgcacctgac gaaacttctc gccatactcg
    10021 caacgcgtca tattggattg ccaggccgag gtaagcctga agggcgttcg ggtcggcgcg
    10081 cgctggccgg tgagccagcg atatcgggcg tctgcatcgt gatagcttat cagcgacact
    10141 acctgtttat ggtgatcgac aatcagcgcc cagtcgtaaa ggccaatcgc catatcgggt
    10201 aaagcgatat cgcgcgcggc agtatcgggc agaatttcga aacgccgccc taaatcataa
    10261 ccaaacagac ccagcgcgcc gccctgaaag ggtaagtcag ggtcaggctg aggatgaaaa
    10321 ggcagcgcct ccagttgagt ctgcaaaacg tgtaacggat cgtcgagagt gacggtagtc
    10381 gtgcgcgcag tacataccgt ggtttcctgg gcgcgcgtgg tcagtgtggt gacaggatcg
    10441 gcgaccagaa tatcaaaacg gttataggga tgaatagcat cacctgaatg cagcagcatc
    10501 gcccagggca aatggtttac gggcgcaaaa tagtgttcag cggcgtccgg acgccagggt
    10561 aaggtgataa cagtgggaga taacgtcttc atcattcctg actcgttaca acactactgg
    10621 cttaccgccg ggtagcgtga aataattagc gctaacaatt tagcaggagt taatcatgtt
    10681 tgcaggttta ccttcactca gtcatgaaca acagcaaaaa gccgtagaac gtatccagga
    10741 attgatgtcg caaggtatga gtagcggaga agcgattgcc caggtggcag gcgaacttcg
    10801 cgccaaccat accggcgaac ggatagtggc gcgttttgag gatgaagacg aataaccggc
    10861 ttataccgcc gcgacaatct taatctcaac tttatatttc gggttcatca acccggcctg
    10921 tacggtacag cgtaccggcg catggcctgc gacgacccac gcatcccacg ccttattcat
    10981 ggcggcaaaa tccgctttat cgctcaggaa aatagtggca tccagaatac gtgacttact
    11041 ggagccctgt ttttccagca ccgcatcaat ttgcgccaga gtattcgccg tttgctcaaa
    11101 agcatcggcg tccaggtttt ccggcacgcc gatataccac agcgtattat tgtagatcac
    11161 cacgtctgac caacgatctt cggcatcaat acgcacgata gacatcactt attcctcatt
    11221 tgctttccat ttgaatggct caagactgcc acaatgtggc gccgccgtca cctctgtaac
    11281 tggcgtaagc ctttctaccc tgacataatc ccctgtgcaa attaacaggg ggcagtgtga
    11341 cggacgattt tgcagcagat ggccaactgg ccaaagcgat aaccggcttt aaaccgcgcg
    11401 aaccacagcg acaaatggcg gttgccgtga cacaagcgat tgaaaatgcg cagcctttgg
    11461 ttgttgaagc cggcaccgga accgggaaga cctatgctta cctcgctccg gcgttgcgcg
    11521 ccgggaaaaa agtcattatt tcgaccgggt cgaaagcgtt gcaggatcaa ctctacagcc
    11581 gcgatctgcc gacggtagca aaagcgttgg cgtttaccgg taagacggcc ctgttgaaag
    11641 gacgttcaaa ctacctctgc ctggagcgtc tggaacaaca agcgctggcg ggcggcgatt
    11701 taccggtaca aacgttaagc gacgtgatat tgctgcgctc ctggtcaaat cagacgcggg
    11761 atggcgatat cagcacctgc gtcagcgtgg cggaggattc ccaggcctgg ccgctggtca
    11821 ccagtaccaa cgacaactgc cttggcagcg attgtccgct ttacaaagag tgctttgtgg
    11881 tgaaagcgcg taaaaaggcg atggacgcgg atgtggtgat tgtaaaccac cacctttttc
    11941 ttgcggatat ggtggttaaa gagagcgggt ttggcgaact tatccctcag gctgaagtaa
    12001 tgatcttcga tgaagcccac caactgcctg acatcgccag ccagtatttc ggacaatcgc
    12061 tctctagccg tcagttgctg gatttagcaa aagacatcac catcgcctac cggacggaac
    12121 tgaaagacac tcaacagttg caaaaatgcg ccgatcgcct tgcccagagc gcccaggatt
    12181 ttcgtctgca actgggggag cccggctacc ggggaaattt gcgtgaactg ttagccgact
    12241 ctcgtatcca acgggcattt ttactgctgg atgatacgct ggagctttgt tacgacgtgg
    12301 cgaaactgtc gctgggccgt tcggcgctgc tggatgcggc ttttgaacgc gccacgctat
    12361 accgttcacg gctgaaacgc ttaaaagaga tcaatcagcc gggatacagc tactggtatg
    12421 agtgcacctc gcgccatttc actctggcgc tgacgccgct caccgtggcg gacaaattca
    12481 aagaggtgat ggaacagaag cccggtagct ggatttttac ctcggccacg ttgtcggtaa
    12541 atgatgatct ccaccacttt accgcccgtc tgggaattga acaggcagaa tccatgctgt
    12601 tgcccagccc attcgactat acgcgccagg cgttactctg cgtaccgcgt aacctaccgc
    12661 aaaccaacca gcccggcgcg gcgcgacagt tggcggctat gctcaggccg attatcgaag
    12721 ccaataacgg gcgatgtttt atgctgtgca cctcacacgc catgatgcgc gatctggcgg
    12781 agcagtttcg cgccaccatg acgctgccgg tattgttgca aggggaaacc agtaaaggcc
    12841 aactgttaca gcaatttgtt agcgccggca acgcgctgct cgtcgccacc agcagcttct
    12901 gggaaggggt ggacgtgcgc ggcgatacgt tatctttggt gattatcgac aaattgccgt
    12961 ttacttcccc ggacgacccg ctgttaaaag cgcgaatgga agactgtcgt ttgcgcggtg
    13021 gcgatccgtt tgatgaggtt caactgcccg atgcggtgat tacgctgaag cagggagtgg
    13081 ggcggctaat tcgcgatgcg gacgatcgcg gggtgttagt gatttgtgat aaccggctgg
    13141 tgatgcggcc ctatggcgcc acgtttctcg ccagcctgcc tcctgcgccg cgcacgcgtg
    13201 atatcgcccg tgccgttcgc tttcttgcga ttccatccgc cgagtaattt gttacggagt
    13261 atggtaagat gcgcgctatt ttattgatct aagcacgaaa cctcatgcga attctggcta
    13321 tcgataccgc cacagaggcc tgttctgtcg ccctgtggaa caacggtact atcaatgctc
    13381 actttgagct ttgtccacga gaacacactc aacgtatcct gcccatggtg caggagattc
    13441 tggccgccag cggcgcctcg ctcaatgaga tagatgcgct ggcgtttggg cgcggtccgg
    13501 gcagctttac cggcgtgcgt atcggcattg ggattgcgca agggctggcg ttaggggcaa
    13561 atctgccgat gatcggtgtt tcgacgcttg ccacgatggc gcagggcgca tggcgtaaaa
    13621 ctggcgcgac ccgcgtactc gccgcgattg acgcgcggat gggcgaagtg tactgggcgg
    13681 aataccagcg tgatgcgcag ggcgtctggc agggcgaaga gacggaagcg gtgctgaaac
    13741 cggaacgggt cggcgagcgg ttgaaacagc tttccggcga gtgggcgacc gtaggaacgg
    13801 gttggtccgc atggcccgat ctggcgaagg agtgcggcct gacgcttcat gatggggagg
    13861 tgtcgctccc ggcagcggaa gatatgttgc ccatcgccag tcaaaagctg gcggcaggag
    13921 agaccgttgc cgtggaacat gccgagccgg tttatttgcg taacgaagtg gcgtggaaga
    13981 aacttcccgg caaagaatga ctctcactac tattaccccc atactttatg ctgtggggtg
    14041 gaatagaggt cgagaaaaag gagtcgcatc atggcggttc aaaaacggtt aataaaaggg
    14101 gcgctggcgt gcgcttttgc gcttatgctg agcggttgcg tgactatccc ggatgccatt
    14161 aaaggttcga gtccgacgcc gcagcaggat ttggtgcggg tgatgaatgc gccgcagctc
    14221 tatatcgggc aagaggcgcg ttttggcggc aaagttgtgg cggtacaaaa tcagcaggga
    14281 aaaacccggc ttgaaatcgc gaccgtaccg ctcgacagcg gcgcgcgtcc tgttctgggc
    14341 gaagcctcgc gcggcagaat ttttgccgat gtgaacggtt ttctggaccc ggtggacttc
    14401 cgtggccagt tagttaccgt tgtcggcccg ataaccggca cggttgacgg taaaatcggc
    14461 aatacgccgt ataaatttat gctgatgcag gctaccggct ataaacgctg gcatcttgtt
    14521 cagcaggtcg tcatgcctcc acagccgatc gatccgtggt tttacggcgg acgcgcctgg
    14581 ccttatggat atggcggttg gggatggtat aaccctgg
//
LOCUS       DAJVBX010000113        14585 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.113, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000113 DAJVBX010000000
VERSION     DAJVBX010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 14585)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14585)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14585
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.113"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            1..552
                     /locus_tag="OPV72_002844"
     CDS             1..552
                     /locus_tag="OPV72_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001517764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HCR9915090.1"
                     /translation="MAMGSTSAMAVEGGQIEFHGLVSATTCSKVVSSSRGNQATDGDV
                     YLTTAAPGDITEGVAANAYGALPAPFSIILDCSGAADVTDATKASLVMDSSFSNTTGT
                     LDNDTTLSVAGETGAENVNIAIHDADTKTQVKIDGAEIHEASFKNKVATYNFMASYVR
                     ADASKEVTTGHVTTNAMYTFTYQ"
     gene            731..1465
                     /locus_tag="OPV72_002845"
     CDS             731..1465
                     /locus_tag="OPV72_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000967611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone"
                     /protein_id="HCR9915091.1"
                     /translation="MLYVKKSLTAIVLASAVFSTFSYADIIISGTRIVYDENKKDVSI
                     RLENKGTRPLLVQNWIDLGNDNDDPGSIKAPFVSTPPVSRVEPKRGQSVKIMYTQASA
                     LPKDRESVFWFNVLEVPPKADTSKEENKSLLQLAFRTRIKLFYRPTGLKGQPAEAAKQ
                     LKWQIASEQGYAVLRADNSTPYFVSFNDATYTAGGKRYDVEATMVAPFSKSSFTVKGL
                     SGASAGKLEYHAINDFGGLIEGSVSL"
     gene            1525..4131
                     /locus_tag="OPV72_002846"
     CDS             1525..4131
                     /locus_tag="OPV72_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015406108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane usher protein"
                     /protein_id="HCR9915092.1"
                     /translation="MPKKTMLAVCCALFYSQSSISAESVEYDSSFLMGSSASTIDISK
                     YSDGNPTPVGTYSVKVFVNENPVSSLSIPFIDIGKVSAEACLTQKNLAQLHIKQPEIN
                     ATNQILKKGEEEDQDCLNLPVAIAHSEVNFDMGEQRLDITVPQAWLIEGYDGYVEPSL
                     WEDGIPAALLSYSANGYHSTNGSADNDSMYAAFNTGINLGAWRFRANGNYNWTKDSGS
                     SFDYQNRYLQRDLPSMRSQLVVGETYTTGETFDSVSIRGARLYSDNRMLPSQLANYAP
                     IIRGVANSNAKVSITQGGYKIYESTVPPGPFEISDISPSGYGSDLIVTVEEADGSKRT
                     FSQPFSSVMQMQRPGVGRWDFSAGEVNDDELHDKPYMAQGSYYYGLNNFLTLYTGVQG
                     TDNNYLAGLLGVGLNTPLGAFALDVTQSRTEIPEDKTYKGQSYRLTWNKLIEPTATSF
                     NVAAYRYSTQDYLGLNDALQLIDDAKHKDADDRNTMLNYSRMKNQVTVSINQPLRFKE
                     VDYGSFFLSGSWTDYWATNESRTDYSLGYGRGFSWGSLSINLQRSWDEDGEKDDSLYI
                     NFNVPLENLLGGGRRKSGFSSLTAQMRTDFDGGYQLSMNSNGSSEDHTLNYSVNTGYT
                     MQKNEKNITDVSGYASYQSPWGDVTASASANNDSSRQYSLATTGDFVLHGGGVTFTND
                     NFGNSDAIVLVKAPGAKGARINGGNSTIDRWGYGATNSLSAYRENQVNIDIDTLENDV
                     ELKSTSTTLIPRDGAVVLASFETDQGRSVILNMSRNDGKALPFGAEVYENDVQIDNMG
                     QGGQAFVRGISDAGELSVRWFEENQPATCLATFALPATQQTVGSSQTLLLDHITCRVN
                     NLKSNGIDNEKE"
     gene            4118..4684
                     /locus_tag="OPV72_002847"
     CDS             4118..4684
                     /locus_tag="OPV72_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000827925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HCR9915093.1"
                     /translation="MKRNKYLLAASVLAVIFPLTSQAENINVDFTATVLATTCSMSIA
                     ALDGSNLSGDATSGYTLNVGDVGLDKIIKKSAESQKNFKFVAKDCSAALTKITTTLAS
                     STDASGNFIKNQSAASGAATNVGMGFKRKSTTDETYFTPGSGSFSWTSDERAANEVEM
                     TVALRELTDGAGTTGAFSSTATFNFTYQ"
     gene            4699..5307
                     /gene="staE"
                     /locus_tag="OPV72_002848"
     CDS             4699..5307
                     /gene="staE"
                     /locus_tag="OPV72_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein StaE"
                     /protein_id="HCR9915094.1"
                     /translation="MKKQILRVVIFSSLIATGAGISTMTYADGTNSLDLTVNANITAG
                     TCSASVVEGDTITDTIAFGNVYISEVYAKSKIKLFKLRFSDCVGLKDKKAKFRLAPNN
                     VACPGSSGTDGQFANASTSTTKAAMVAMEVWTTETPGGTGAVKLHCWSKPEQTVDLSG
                     ASVTTPVDFPLSAMMVAQSGGTLQNMTAGDFYSPTTFTITYQ"
     gene            5319..5903
                     /locus_tag="OPV72_002849"
     CDS             5319..5903
                     /locus_tag="OPV72_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001253684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HCR9915095.1"
                     /translation="MRRLREPTLATLFSGLATALFSATLYADTNVNFTASVQKDTCQI
                     KIDGNGTVNFATIAPAYFADGITAETDYEGGKEFTIKLISCPISDGKITNVTFNFAPL
                     NGQFSPENQQVFPNDIATDAGGVDNVGVVIFTTDSPRTNVLNTDGSSRATFAASTYSD
                     TVWTFYSRMQKIRSAEKVTTGELSSRVLVNVSYE"
     gene            5940..7115
                     /locus_tag="OPV72_002850"
     CDS             5940..7115
                     /locus_tag="OPV72_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000925246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial-like adhesin"
                     /protein_id="HCR9915096.1"
                     /translation="MLLKNTTWFAAFFLMMAIMSNCYAINTTLAVGDYASSEHDGPSG
                     DSVFTDNSHNFGQTIAIHKETALRQITVFNWSGIQYVMEMFCNGSGNHTYLQLTHNYI
                     SAGKSYNGHPLYKTSIPGFYFTIEMTFLQPAENMTSSTFWFDKTSTPITSEFTEFPSA
                     CSRTNVYSNLGKLMYGLKIYAYVDSDFAPTEAQLQSFTLSKNGDSDFYIDNPGSGLSN
                     YKMKFNLAATGLKAVWPTCSASTISGTNVSGSTVKLGSFYPKQIMEGLSPTKFQINLS
                     SCQYINNIEVKLASNNVGTKNTSLLTNNSTSNTKASGIGVLIEGLKSSSSAQMVLKPN
                     DSSSIYKDTTNNTGDGSPVGSATKSLYFQATLKPDGDNPTINPGDFKATAQFSITYP"
     gene            7225..8019
                     /gene="panB"
                     /locus_tag="OPV72_002851"
     CDS             7225..8019
                     /gene="panB"
                     /locus_tag="OPV72_002851"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HCR9915097.1"
                     /translation="MSKPTTIAVLQKCKQEKKRFATITAYDYSFAKLFADEGINVMLV
                     GDSLGMTIQGHDSTLPVTVEDIAYHTRAVRRGAPNCLLLSDLPFMAYATPEQAFENAA
                     IVMRAGANMVKIEGGAWLVDTVKMLTERAVPVCGHLGLTPQSVNIFGGYKIQGRGDAG
                     QILLDDALALEAAGAQLLVLECVPVELAKRVTEALSIPVIGIGAGNVTDGQILVMHDA
                     FGITGGHIPKFAKNFLAEAGDMRAAVRQYMAEVESGVYPGEEHSFH"
     gene            8145..8999
                     /gene="panC"
                     /locus_tag="OPV72_002852"
     CDS             8145..8999
                     /gene="panC"
                     /locus_tag="OPV72_002852"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HCR9915098.1"
                     /translation="MLIIETLPLLRQHIRRLRQEGKRVALVPTMGNLHDGHMKLVDEA
                     KARADVVIVSIFVNPMQFDRPDDLVRYPRTLQEDCEKLNKRKVDYVFAPAVEEIYPQG
                     LEGQTYVDVPGLSTMLEGTSRPGHFRGVSTIVSKLFNLIQPDIACFGEKDFQQLALIR
                     KMVADMGYDIEIVGVPIIRAKDGLALSSRNAYLTAEQRKIAPGLYNVMNSIAEKLIAG
                     NRELQEIIAIAEQELNEKGFRADDIQIRDADTLLELTETSKRAVILAAAWLGQARLID
                     NQSVTLAQ"
     gene            9094..9474
                     /gene="panD"
                     /locus_tag="OPV72_002853"
     CDS             9094..9474
                     /gene="panD"
                     /locus_tag="OPV72_002853"
                     /EC_number="4.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase"
                     /protein_id="HCR9915099.1"
                     /translation="MIRTMLQGKLHRVKVTQADLHYEGSCAIDQDFLDASGILENEAI
                     DIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCAEVGDIVIIASFVTMSDEEARTWR
                     PKVAYFEGDNEMKRTAKAIPVQVA"
     gene            complement(9481..10710)
                     /locus_tag="OPV72_002854"
     CDS             complement(9481..10710)
                     /locus_tag="OPV72_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HCR9915100.1"
                     /translation="MVMRVVLILLFFFAGNVLAALPARYMQTTKDAAIWSQIGDKMVT
                     VGNIRAGQILSVTPVAVDYYAFKFGFGVGFIDKGHLGPVQGKQKVEDGLGDLNKPLSN
                     QNLVTWKDTPVYNAPDISSAPFGVLVDNLRYPIISKLKGRLHQTWNQIRIGDRLAYVN
                     AMDAQEDNGIPILTYHHILRDEENTRFRHTSTTTSVRAFSNQMTWLRDRGYATLTMYQ
                     LEDYIYNRANFPARAVAITFDDGLKSVSRYAYPVLKQYDMKATAFIISSRIKRHPQKW
                     NPRSLQFMSVSELRKISDVFDFQSHTHFLHRVDGHRRPILYSRSYHNILFDFERSRRA
                     LTQFTPHVFYLSYPFGGYNATAIKAAKDAGFHLAVTTVRGKVKPGDNPMLLKRLYILR
                     TDSLETMSRLIVNQPQG"
     gene            complement(10772..11212)
                     /locus_tag="OPV72_002855"
     CDS             complement(10772..11212)
                     /locus_tag="OPV72_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCR9915101.1"
                     /translation="MLGWVITCHDDRAQDMLDRLERKNGPLAQCRAVNFWRGLSSNML
                     SRMMCDALHATDSGEGVIFLTDISGAAPYRVASLMSHKHPQCEVISGISYSLIEEMIP
                     LRESMSSSAFRDQIVALGAPDVTSLWHQQQKNPPFVLLHDLYEF"
     gene            complement(11317..12087)
                     /locus_tag="OPV72_002856"
     CDS             complement(11317..12087)
                     /locus_tag="OPV72_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001747261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR9915102.1"
                     /translation="MMQLYWVALKSIWAKEIHRFMRIWVQTLVPPVITMTLYFIIFGN
                     LIGSRIGEMHGFSYMQFIVPGLIMMAVITNSYANVASSFFSAKFQRNIEELLVAPVPT
                     HVIIAGFVGGGVARGLCVGILVTAISLFFVPFQVHSWVFVALTLILTAILFSLAGLLN
                     AVFAKTFDDISLIPTFVLTPLTYLGGVFYSLTLLPPFWQGLSHLNPIVYMISGFRYGF
                     LGIHDVPLVTTFGVLVIFIATFYLLCWSLIQRGRGLRS"
     gene            complement(12084..13010)
                     /locus_tag="OPV72_002857"
     CDS             complement(12084..13010)
                     /locus_tag="OPV72_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR9915103.1"
                     /translation="MTIALELQQLKKTYPGGVQALRGIDLQVEAGDFYALPGPNGAGK
                     STTIGIISSLVNKTSGRVNVFGYDLEKDVVNAKRQLGLVSQEFNFNPFETVQQIVVNQ
                     AGYYGVEHKEAVLRSEKYLKQLDLWEKRHERARMLSGGMKRRLMIARALMHEPKLLIL
                     DEPTAGVDIELRRSMWGFLKDLNAKGTTIILTTHYLEEAEMLCRNIGIIQHGELVENT
                     SMKNLLSKLKSETFILDLAPKSPLPKLTGYQYRLVDTSTLEVEVLREQGVNSVFSQLS
                     EQGVQVLSMRNKANRLEELFVSLVHEKQGDRA"
     gene            13119..13781
                     /gene="can"
                     /locus_tag="OPV72_002858"
     CDS             13119..13781
                     /gene="can"
                     /locus_tag="OPV72_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonate dehydratase"
                     /protein_id="HCR9915104.1"
                     /translation="MKDIDTLISNNALWSKMLVEEDPGFFEKLAQAQKPRFLWIGCSD
                     SRVPAERLTGLEPGELFVHRNVANLVIHTDLNCLSVVQYAVDALEVEHIIICGHSGCG
                     GIKAAVENPELGLINNWLLHIRDIWLKHSSLLGKMPEEQRLDALYELNVMEQVYNLGH
                     STIMQSAWKRGQNVTIHGWAYSINDGLLRDLDVTATNRETLENGYHKGISALSLKYIP
                     HQ"
     gene            complement(13839..14375)
                     /gene="hpt"
                     /locus_tag="OPV72_002859"
     CDS             complement(13839..14375)
                     /gene="hpt"
                     /locus_tag="OPV72_002859"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004204384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HCR9915105.1"
                     /translation="MKHTVEVMIPEAEIKARIAELGRQITERYKDSDSEMVLVGLLRG
                     SFMFMADLCREVQVPHEVDFMTASSYGSGMSTTRDVKILKDLDEDIRGKDVLIVEDII
                     DSGNTLSKVREILGLREPKSLAICTLLDKPSRREVDVPVEFVGFSIPDEFVVGYGIDY
                     AQRYRHLPYVGKVVLLDE"
BASE COUNT         3897 a         3800 c         3524 g         3364 t
ORIGIN      
        1 atggctatgg gttctacttc cgcaatggca gttgaaggcg gccagatcga attccacggt
       61 ttagtgagcg caacaacctg ttctaaagta gtttcctctt cacgcggtaa tcaagcgact
      121 gatggtgacg tatatctgac tacagcagcc ccaggcgata tcactgaagg cgttgctgct
      181 aacgcatacg gcgcgcttcc ggctccgttc tctatcatcc tggattgctc aggcgcggct
      241 gatgtaactg atgccactaa ggcttctctg gtaatggatt cgtcattctc taacactacc
      301 ggcactcttg acaatgacac cacactgtcc gtggctggtg aaactggggc tgaaaacgtg
      361 aatatcgcca tccatgatgc cgataccaaa actcaggtta aaatcgatgg cgctgaaatt
      421 catgaagcgt ccttcaaaaa caaagttgca acctataact ttatggcgtc ttacgttcgt
      481 gccgatgctt ctaaagaagt gactaccggt catgtaacca cgaacgcaat gtataccttt
      541 acttaccagt aacaggacat acggttatca ctaataagta ctcgtacctt tccttgagtt
      601 agcgtgctta tcagttattg atctcatata accttcgggg tccaggaatt atttcaacga
      661 ttccgggggt tcattcaatt taattaaatt caaagttgat ttcattatct tctacaggca
      721 aggaacgctt atgttgtatg taaaaaaaag cctgaccgcc atcgtattag ccagtgctgt
      781 atttagtacc tttagctatg cggatattat tatctcgggc accagaatcg tttatgacga
      841 aaataaaaaa gacgtcagta tacgactgga aaataagggt acccgcccat tattagtcca
      901 aaactggata gacctgggta acgataacga cgatcccggg agtattaaag cgcctttcgt
      961 ttctaccccc ccggtttcac gcgttgagcc taaacgtggg caatcggtaa aaattatgta
     1021 tacccaggcc agcgcgctgc cgaaagaccg ggaaagcgtc ttctggttta acgtactgga
     1081 agtaccgcca aaagcggata ccagcaaaga agagaataaa agcttactgc aactggcttt
     1141 tcgtacccgt atcaaactgt tctatcgccc aacaggacta aaaggccagc ctgctgaagc
     1201 ggcaaaacaa ctgaagtggc aaatagcgag cgaacaaggc tacgcggtac tacgtgctga
     1261 taactcaact ccgtatttcg tctcatttaa tgacgctacc tacactgcag gcggtaaacg
     1321 ttatgacgtt gaagccacca tggttgcgcc tttcagtaaa tcatccttca ccgtgaaagg
     1381 cttgtcaggc gctagcgccg gaaaactgga gtatcacgcc attaatgatt ttggcggttt
     1441 gattgaaggt tccgtatcgc tgtaacggat taaccaagaa tcaggatgaa gaaatcggtg
     1501 taaaactttc cacattccaa ggccatgccg aagaaaacga tgctcgcagt ttgctgtgcg
     1561 ctattttata gccagagcag tatttccgct gaaagcgttg aatacgacag ttccttttta
     1621 atggggagta gcgcctccac aatcgatatc agcaaatact ccgacggcaa cccaacgcct
     1681 gtcggaacgt atagcgtgaa agtttttgtc aacgaaaacc ccgtatcaag cctgtccata
     1741 ccctttatcg atatcggcaa ggtcagtgca gaagcctgcc tgacacaaaa aaatctggcg
     1801 cagttgcata tcaaacagcc agaaatcaat gcgaccaatc aaattctgaa aaaaggggag
     1861 gaagaagatc aagattgtct gaaccttccc gtcgccatcg cgcattcaga ggtcaatttt
     1921 gatatgggcg aacagcgtct ggatattacc gtacctcagg cgtggctcat tgaaggttat
     1981 gacggctatg ttgagccttc gctgtgggaa gatggtattc cggcagcgct tctgtcctac
     2041 tcggctaacg gctatcacag caccaatggc agcgccgata atgacagtat gtatgcggcg
     2101 tttaacaccg gtattaacct cggcgcatgg cgttttcgcg ccaacggcaa ctataactgg
     2161 acgaaagact caggaagctc ctttgactat cagaatcgct acttgcagcg cgatctgcct
     2221 tcaatgcgct ctcaacttgt tgtcggtgaa acctatacca cgggcgaaac atttgactcc
     2281 gtaagcattc gcggggctcg tctgtatagc gacaaccgaa tgctaccttc gcagcttgcc
     2341 aactatgcgc cgattattcg cggcgtagca aacagtaacg ccaaggtcag cataacccag
     2401 ggcggctaca aaatttatga gtccacggta ccgccaggcc cctttgaaat cagcgacatc
     2461 agtccttccg gctacggtag cgacctcatc gtcaccgttg aggaggccga cggcagtaaa
     2521 cgcaccttta gccagccatt ctcctcggtt atgcagatgc agcgcccggg cgtcggacgt
     2581 tgggatttca gcgccggtga agtgaatgac gatgagcttc atgacaagcc ctatatggcg
     2641 caaggttcat attactacgg ccttaataac tttttgaccc tctatacagg tgttcaggga
     2701 acagataata actatcttgc cgggttgctg ggtgtcggcc tcaacacccc tcttggcgca
     2761 tttgcacttg atgtcactca gtctcgtaca gagatccctg aggataaaac ctataagggc
     2821 cagagctacc gactgacgtg gaacaagctg attgaaccga cggcaacctc ctttaacgta
     2881 gcggcatatc gttattcaac gcaggactac ctgggcctga atgatgcgct acagctgatt
     2941 gatgacgcga aacataaaga cgcggacgat cgcaacacca tgcttaacta ttcgcgcatg
     3001 aaaaaccagg tcacggtcag cataaaccaa ccgttgaggt ttaaggaagt cgactacggt
     3061 tcctttttcc tctcaggctc ctggaccgac tactgggcta ccaatgaaag ccgtaccgac
     3121 tatagcctcg gttacggaag aggtttttcg tggggcagcc tcagtatcaa cctccagaga
     3181 tcctgggatg aagatggcga aaaagatgat tcgctctata tcaacttcaa cgttccgctg
     3241 gagaatctgc tgggcggcgg tcgccgtaag tcgggtttca gctcactgac ggcgcaaatg
     3301 cgcactgatt ttgacggcgg gtaccagttg agcatgaaca gcaacggcag cagtgaagac
     3361 cacacgctga actacagcgt taacaccggc tacaccatgc agaaaaatga aaagaacatc
     3421 accgatgtca gcggctacgc cagctatcag tccccctggg gagatgttac tgcttcagcc
     3481 tctgccaata atgacagcag ccgacaatat tcgctcgcca caaccggaga ctttgtcctg
     3541 catggcggtg gagtgacgtt cactaacgat aacttcggta atagcgatgc catcgtgctg
     3601 gtaaaagccc ctggcgcgaa aggcgcgcgc atcaatggcg gcaacagcac catcgatcgc
     3661 tggggctacg gcgcgacgaa ctcgctttcc gcctacagag aaaaccaggt caatattgat
     3721 atcgacacgc tggaaaacga tgtcgaacta aagagcacca gtacaaccct gataccgcgt
     3781 gatggcgcgg tagtcttagc cagtttcgaa actgaccagg gacgctcggt cattctcaac
     3841 atgtcccgta atgacggaaa agccctacca tttggcgcag aagtctacga gaacgatgtg
     3901 cagatcgaca acatgggcca gggcggtcag gcttttgttc gcggcatcag cgatgcaggc
     3961 gaactctcag tacgctggtt tgaagaaaac cagccagcaa cttgtttagc aacctttgcg
     4021 ttgccggcaa cgcaacaaac ggtagggtcc agccagacct tactgttaga ccacataacc
     4081 tgtcgtgtta ataaccttaa atcaaatgga atagacaatg aaaaggaata aatacctttt
     4141 agcagcctct gtgctcgccg tgatatttcc gcttaccagt caggcggaaa atatcaacgt
     4201 cgactttacc gccaccgtgt tagccacgac ctgcagcatg tcaattgcgg cgttagatgg
     4261 ctcgaactta tcgggtgatg ccaccagcgg ctatacgctg aacgtcggcg atgtcgggtt
     4321 ggataaaatt ataaaaaaat cagcggaatc gcagaaaaac tttaagtttg tcgcgaagga
     4381 ttgcagtgcc gctctgacca aaatcaccac cacgcttgcc agctccacag atgccagcgg
     4441 caattttatc aaaaaccaat cagcggcaag cggcgctgcc accaatgttg gcatgggctt
     4501 taagcgcaaa agcactaccg atgaaaccta tttcacgccc ggctcaggct catttagctg
     4561 gacttccgac gagcgcgcag caaacgaagt ggaaatgacg gtcgcgctgc gtgaactgac
     4621 cgacggcgcg ggtaccacag gtgctttcag ctcaaccgct acgtttaact tcacttatca
     4681 ataacaagga cgatgataat gaaaaagcaa atattgcgcg tcgtgatttt tagctcgctg
     4741 attgccacgg gagctggcat atcaacgatg acatatgccg atggaaccaa cagtctggac
     4801 ctgaccgtga acgccaatat cactgcgggt acgtgttctg catccgtggt tgaaggtgat
     4861 accattaccg atactatcgc ttttggcaac gtttacattt ctgaagtata tgcaaaaagt
     4921 aaaataaaac ttttcaagtt acggttcagt gattgtgtcg gtctcaaaga taaaaaagct
     4981 aagttcagac tagccccaaa taatgtagca tgcccgggga gcagcggcac tgatgggcaa
     5041 ttcgcaaatg cctcgacttc aacaacaaag gcagcaatgg tcgccatgga agtatggacg
     5101 acagaaaccc ctggaggcac tggcgcggta aaacttcact gctggtcgaa accagaacaa
     5161 accgtggatt tatctggtgc aagtgtaaca acgcctgttg attttccttt aagcgctatg
     5221 atggtcgctc aaagcggcgg tacgcttcaa aatatgacag cgggagattt ctactcgccc
     5281 accaccttca ccatcactta ccagtaatgg tgataccaat gagacgtttg cgcgaaccca
     5341 cgctcgccac gttattttca gggctggcaa cagccctgtt tagcgcgacg ctgtacgccg
     5401 ataccaatgt gaatttcacc gccagcgtgc agaaggacac ctgccagata aagatagatg
     5461 gcaatggaac ggtaaacttc gccaccatag cgcccgccta ttttgccgat ggcattaccg
     5521 cggaaaccga ttatgagggg gggaaagagt tcaccattaa gcttatttct tgcccgatca
     5581 gtgatggtaa aataaccaat gtcaccttta atttcgcacc actaaacggg cagttctcac
     5641 ctgagaatca acaagttttt cctaatgaca tcgctaccga tgctggtggc gtagacaatg
     5701 tcggcgtggt gattttcacc accgattcac cacgcaccaa cgtgcttaat acggatggtt
     5761 catcgcgggc gacttttgct gccagcacct acagcgacac cgtctggacc ttttactcca
     5821 gaatgcaaaa aatacgcagt gccgaaaaag tgacgaccgg tgaacttagc agccgtgtac
     5881 tggtgaatgt ctcctatgaa taatcaggag attttattaa acgaaaggat atcgttaata
     5941 tgcttttaaa aaacacaaca tggtttgccg cctttttcct gatgatggct atcatgtcca
     6001 actgttatgc cataaatact accctggccg ttggcgacta cgcctccagt gaacatgatg
     6061 gcccaagcgg ggattcggta ttcactgata acagccacaa ttttgggcag accatcgcga
     6121 ttcataagga aacggcgctg cgccagatta ccgtttttaa ctggtccggc atccagtacg
     6181 ttatggagat gttctgtaac ggcagcggca accacaccta ccttcaactg acccataatt
     6241 atatctctgc tggcaaaagc tataatggac atccgctgta taaaacctca attcccggtt
     6301 tttatttcac cattgagatg accttccttc agccagcaga gaatatgacc tcaagcacct
     6361 tctggtttga taagacctca acgccgatca ccagcgagtt cacggaattt ccgtcagcct
     6421 gctccagaac aaatgtttat agcaaccttg gcaaattaat gtatggcctg aaaatctatg
     6481 cctatgtcga ctctgacttc gcgccgacgg aagcccagct tcaaagcttt acgctgtcta
     6541 aaaacggcga ctccgatttc tacattgata acccgggcag cggattatca aactataaaa
     6601 tgaagtttaa cctcgccgcc acaggactta aggccgtctg gccaacctgc tcggccagca
     6661 ccattagcgg caccaatgtt tcgggatcaa cggttaagct gggtagcttt tatccaaagc
     6721 agattatgga agggctgtcg ccgaccaagt tccagatcaa tctctcctcc tgccagtaca
     6781 tcaataatat tgaagttaaa ttggccagta ataatgtcgg gacgaaaaac acctcgctac
     6841 taaccaacaa ttcaaccagc aacacgaaag ccagcggcat tggcgtttta attgaaggtt
     6901 tgaaaagtag ttcgagcgcc cagatggtac tcaaacctaa cgactcaagc tcaatttata
     6961 aagataccac caataacacc ggagacggca gcccggtagg aagcgcgaca aaatcgttgt
     7021 atttccaggc aaccttaaag cccgatggtg acaatccaac aatcaatcca ggtgatttca
     7081 aagccaccgc tcaattttca atcacctatc cgtaaaatcc tataacgaac cgcaacgcaa
     7141 tttgcccaga aaaggctaac gcttgcggtt ctcttcccct acaatgcggc cattctattc
     7201 atcaatatta tggccggaga ggttatgagc aaacccacta ctatcgctgt gctgcagaaa
     7261 tgcaaacaag agaaaaagcg cttcgccacc attaccgcgt acgattacag cttcgccaaa
     7321 ctcttcgccg atgaaggcat caatgtgatg ctggttggcg actcgctggg catgacaatt
     7381 caggggcacg actccaccct gcctgtcacc gtggaagata tcgcctacca cacccgcgcg
     7441 gtacgccgcg gcgcgccgaa ctgcctgctg ctctccgacc tgccgtttat ggcttacgcc
     7501 acgccggaac aggcgtttga aaacgcggct atcgtgatgc gtgcgggggc caacatggtc
     7561 aaaatcgaag gcggcgcatg gttggttgat acggtgaaaa tgctcaccga acgcgccgtg
     7621 ccggtgtgtg gccatctggg attaactccc cagtcggtga atatcttcgg cggctataaa
     7681 attcagggcc gcggcgatgc cgggcagata ctgctggatg atgcgctggc cttagaagca
     7741 gcgggcgctc aactgctggt gctggagtgc gtgccggttg aactggcgaa gcgcgtcacg
     7801 gaagcgctgt cgattccggt gatcggcatc ggcgcgggca acgtcaccga cggtcagatc
     7861 ctggtgatgc acgatgcgtt tggcatcacc ggcggtcata ttccaaaatt cgcgaaaaat
     7921 ttccttgccg aggcgggcga catgcgcgcc gccgtacggc agtatatggc agaagtggag
     7981 tccggcgttt atccgggcga agaacacagc tttcactaat ttttctgacc gtgccggata
     8041 gcgacgcgac gcgtcttatc cggcctacag atcctcaacg gatgtaggcc tgataagcgc
     8101 agcgccatcg ggctggatca tcaagcaact caaggagtct tgttgtgtta atcattgaaa
     8161 ccctgccgct gctgcgccag catattcgcc gtctgcgtca ggaaggcaaa cgcgtcgcac
     8221 tggttcccac tatgggcaac ctgcacgacg gccatatgaa gctggtcgat gaggcaaaag
     8281 cccgggccga tgtggtcatc gtcagcattt tcgtcaaccc gatgcaattt gatcggccgg
     8341 acgatctggt gcgctatccg cgcacgttgc aggaagattg tgaaaagctg aacaaacgca
     8401 aagtcgatta tgtctttgcc ccagccgttg aggaaatcta ccctcagggg ctggaaggac
     8461 agacatacgt tgacgttccc ggcctctcta ccatgctgga aggcaccagc cgtccgggcc
     8521 acttccgcgg cgtctcgacc atcgtcagca agctgttcaa ccttatccag ccggatatcg
     8581 cctgctttgg cgagaaagat ttccagcagc tggcgctgat ccgcaaaatg gtggcggata
     8641 tgggttatga cattgagatc gtcggtgtgc cgattattcg cgctaaagac ggtctggcgc
     8701 tcagctcacg taacgcttat ctgactgcag agcagcgcaa aattgcgccg ggtctataca
     8761 acgtgatgaa tagcatcgct gaaaaactga ttgcgggtaa tcgtgagctg caagagatta
     8821 ttgccattgc cgagcaggaa ctgaatgaaa aaggcttccg tgccgacgac attcaaatcc
     8881 gtgatgccga cacgctgctg gagctgacgg aaaccagcaa acgcgcagtg attctggctg
     8941 ccgcctggct gggacaggcg cgtctgatcg ataatcaaag cgttacatta gcccagtaga
     9001 caggggttaa aaatcgggca atactgcctg agaatttcca aagcaggcta caagcgcctg
     9061 cttagccaag ataaacgaca gggtatagaa gttatgattc gcaccatgct gcaaggcaag
     9121 ctccaccgcg taaaagtcac gcaggcggac ctgcactacg aaggctcctg cgccattgac
     9181 caggatttcc ttgatgcctc cggtattctg gaaaacgaag cgattgatat ctggaacgtg
     9241 accaatggga aacgtttctc aacctatgcg attgcggctg aacgcggctc cagaatcatc
     9301 tcggtgaacg gtgcggcggc gcactgcgct gaagttggcg acattgtgat tatcgccagc
     9361 ttcgtcacca tgtctgatga agaagcgcgt acatggcgtc cgaaagtggc ctactttgaa
     9421 ggcgacaacg aaatgaagcg caccgcgaaa gccattccgg ttcaggttgc ctgatagtcc
     9481 ttacccctgc ggctgattga ctatcagccg cgacatcgtt tccagcgaat ccgtgcgtaa
     9541 aatatacagc cttttgagca gcatcggatt atctcccggc ttcaccttcc ctctcaccgt
     9601 ggtgaccgcc agatggaaac cggcgtcttt tgctgctttg atcgcggtcg cgttatagcc
     9661 gccaaaggga taagaaagat aaaatacgtg cggagtaaac tgtgtgagcg cccgccgcga
     9721 acgttcaaaa tcaaacagaa tattatggta actgcggcta tataaaatcg ggcggcgatg
     9781 cccgtctacc cggtgtaaaa aatgggtatg cgactgaaaa tcaaaaacat cgcttatctt
     9841 gcgcaattcg gacacgctca taaattgcag cgacctggga ttccattttt gcggatggcg
     9901 cttaatacgc gatgagataa taaatgccgt cgctttcata tcgtactgct ttaataccgg
     9961 atatgcatag cgactcaccg atttaaggcc atcatcaaag gtgatagcca ccgcgcgcgc
    10021 cgggaaatta gcgcggttat agatgtaatc ctccagttgg tacatcgtca acgtggcata
    10081 gccgcgatcg cgaagccagg tcatttggtt gctgaatgcc cgaaccgaag tcgtggtgga
    10141 ggtatggcga aaacgggtat tctcttcatc acgtaaaatg tgatgatagg tcaaaatcgg
    10201 aatgccgttg tcttcctgcg catccatggc gttgacataa gccagcctgt cgccaatacg
    10261 gatctgattc caggtttgat gtagccggcc tttcagcttg ctaataatgg ggtaacgcaa
    10321 attatccacc aatacgccaa acggggcgct actgatgtcc ggcgcgttat acaccggcgt
    10381 gtccttccag gtcaccagat tctgattgct gagcggcttg ttaagatcgc ccagcccatc
    10441 ttccactttt tgttttccct gcacgggtcc cagatggcct ttatcgataa accccacacc
    10501 gaagccaaat ttaaaggcat aataatcaac cgcaacaggc gttacggaaa gaatttgtcc
    10561 ggcgcggata ttccctacgg tcaccatttt gtcgccaatc tgcgaccaga tggcggcatc
    10621 tttcgtcgtt tgcatataac gagcgggcaa ggcagccaac acattaccgg cgaaaaagaa
    10681 cagcaagata agaacaacac gcataaccat atatcataac cgaggcgaaa aaacgccgtt
    10741 attgtagcaa aagcgtcgtc aatggtattg atcaaaactc atacaaatca tgcagcaata
    10801 caaaaggcgg atttttctgc tgctgatgcc agagactggt gacatccggc gcgccaagcg
    10861 cgacaatctg gtcacgaaat gctgaactgc tcatcgactc tcgcaaagga atcatttcct
    10921 ctatcaatga atagctaatg cctgaaataa cttcacattg aggatgttta tggctcatca
    10981 gcgacgctac acgataaggc gccgcgccgg aaatgtcggt taaaaatatc acgccttcac
    11041 cggaatcggt ggcatggagg gcatcacaca tcatgcggct cagcatgttt gagctcagac
    11101 cgcgccaaaa attgaccgcc cggcattgcg ccagcggacc attttttctc tccaggcgat
    11161 caagcatatc ctgtgcacga tcgtcatggc aggtaatcac ccaacctaac ataacctacc
    11221 tccttagcag gcaagtagtt tatcagggtg atcaatcggg aatgatgaca gccgtcaaaa
    11281 gtctcctctt ccctccagga gaagaggaga atcgtatcag ctacgcaaac cgcgtccgcg
    11341 ctggatcagc gaccaacaca gcagatagaa agtagcgata aagatcacca gtacgccaaa
    11401 cgttgtcacc agcggcacat catggatacc cagaaaacca taacggaaac cgctgatcat
    11461 gtagacgatc gggttcaggt gcgacaaccc ttgccagaac ggcggcagca gcgtcagcga
    11521 gtaaaatacc ccgccgaggt aggtcagcgg cgtcagcaca aaggtcggga tcagactgat
    11581 atcgtcaaag gttttggcaa acacggcgtt cagcagtccg gccagcgaga acagaatcgc
    11641 ggtcagaatc agcgttagcg cgacaaatac ccaggaatgc acctggaaag gcacgaaaaa
    11701 gagcgaaatc gccgtcacca gaatccccac gcacagcccg cgcgccacgc cgccgccgac
    11761 aaatccggcg atgatcacgt gcgttggcac cggcgcgacc agcagttcct caatattgcg
    11821 ctgaaacttg gcgctaaaga acgaggaggc cacattggcg taggagttag taatgaccgc
    11881 catcataatc aggcccggca caataaattg catatagcta aagccatgca tttcgccgat
    11941 gcgcgaaccg atcaggttac cgaaaataat aaaatagagc gtcatggtga tgacaggcgg
    12001 caccagcgtt tgcacccaga tccgcataaa gcggtggatc tctttcgccc agatgctttt
    12061 aagggcaacc cagtaaagct gcatcatgcg cgatctcctt gtttttcatg caccagcgac
    12121 acaaacagtt cttccagacg gttggcttta ttacgcatac ttaatacctg aaccccctgc
    12181 tcgctcagtt ggctaaagac gctgttaacc ccctgctcgc gtaacacttc cacctccaga
    12241 gtcgaggtat ccaccagacg atattgataa cccgtaagct taggtagcgg gcttttgggc
    12301 gctaaatcca gaataaatgt ctccgatttc agctttgaaa gcagattttt catggaagta
    12361 ttttccacca gctcgccgtg ctgaataata ccgatattgc ggcacagcat ttccgcctct
    12421 tccagatagt gggtggtgag aataatggtg gtgcctttgg cgtttaagtc tttcaggaac
    12481 ccccacattg agcgacgtaa ttcgatatcg acgcccgccg tcggctcgtc gagaatcaat
    12541 agtttaggct catgcatcaa tgcgcgggcg atcatcaggc ggcgtttcat cccaccggac
    12601 agcatccgcg cgcgttcatg acgtttttcc cacagatcga gctgttttaa atacttttcg
    12661 ctacgtaaaa ccgcctcttt atgctccacg ccgtaataac ccgcctgatt cactacgatc
    12721 tgttgcaccg tttcaaacgg gttaaagtta aactcctgtg acaccagtcc aagctgtcgc
    12781 ttggcgttaa ccacgtcttt ttccaggtcg taaccaaaaa cgttaacgcg cccggacgtt
    12841 ttattaacca atgagctgat aataccgatg gtggtcgatt tccctgctcc atttggcccc
    12901 ggaagcgcgt aaaaatcccc cgcttcgacc tgcaaatcta tgccgcgcag cgcctgaacg
    12961 ccgccgggat aggttttttt aagttgttga agttccagcg caatggtcat aaattctcac
    13021 ttactttacg ttcttacact ttatatatgg tttaaataat tacggagttg ccctatatta
    13081 gcccaacgca cttatttggt tacaggtcgt taacttccat gaaagacata gatacactca
    13141 tcagcaacaa tgcactatgg tcaaaaatgc tggtggaaga ggaccccgga ttttttgaga
    13201 aactggcgca agcgcaaaaa ccgcgctttc tatggattgg atgttccgac agccgcgttc
    13261 ccgcagagcg tttaaccggg cttgaaccgg gcgaattgtt tgttcaccgt aatgtggcta
    13321 acctggttat tcacaccgat ctgaactgtc tctccgtggt tcagtatgcg gtagatgctc
    13381 tggaagttga gcatattatc atttgcggcc actccggttg cggcggtatc aaggctgcgg
    13441 tagaaaaccc tgagctgggc ttgattaata actggctgct gcatatccgc gacatctggc
    13501 ttaaacatag ctcgctgttg ggaaaaatgc ccgaagagca acgtctggac gcgctctatg
    13561 aattgaacgt catggagcag gtctataacc tggggcattc caccattatg cagtcagcgt
    13621 ggaaacgcgg gcagaatgtg accattcacg gctgggcgta cagtatcaat gatggcctgc
    13681 tgcgcgatct tgacgtcacc gccaccaaca gagaaacgct ggagaacggc tatcataagg
    13741 gtatctccgc cctaagtctg aaatacattc cccaccaata agccattagc tataggccgg
    13801 ataagtcgct ttagcgacgc catccggcat ttctgcgctt actcgtccag cagcaccact
    13861 ttaccaacat acggtagatg gcgataacgc tgggcgtagt cgataccgta accgactaca
    13921 aattcgtccg gaatcgaaaa gccaacgaac tcaaccggca cgtccacttc tcggcgagac
    13981 ggcttatcca gcagcgtaca aatcgccagc gatttcggct cgcgcaggcc caggatttca
    14041 cggaccttcg acagcgtatt accggaatca ataatgtctt cgacaatcag cacgtcttta
    14101 ccacgaatat cctcatccag atctttgagg attttcacgt cgcgggtggt ggacataccg
    14161 ctaccataac tggaggcggt cataaaatcg acttcatgag gaacctgaac ttcacggcac
    14221 aggtccgcca taaacataaa tgagccacgc aacagaccta ccagcaccat ttcactgtcg
    14281 ctgtctttat aacgttcggt aatctgacga cccagctcgg caatacgtgc tttgatctcc
    14341 gcttcgggga tcatgacttc aacagtatgt ttcatattta taaccatatg atttaaaaac
    14401 aaatcactca atgccggtga ctaataacgc cgcattgacg cgcaaggcac gcagtataac
    14461 agcaaacgta ttcattcgcg gcatttgata agaaagctca ttttgtgatg acgatcacac
    14521 atgttaattc ctatgcttaa ttgctactaa aaaattaaca atttgggatg gtgtcttttt
    14581 atggc
//
LOCUS       DAJVBX010000114        14488 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.114, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000114 DAJVBX010000000
VERSION     DAJVBX010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 14488)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14488)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14488
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.114"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(79..813)
                     /gene="pxpA"
                     /locus_tag="OPV72_002860"
     CDS             complement(79..813)
                     /gene="pxpA"
                     /locus_tag="OPV72_002860"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpA"
                     /protein_id="HCR9915106.1"
                     /translation="MNIDLNADLGEGCASDSELLTLVSSANIACGFHAGDAQTMLTCV
                     REALKNGVAIGAHPSFPDRDNFGRTAMVLPPETVYAQTLYQIGALGAIVQAQGGVMRH
                     VKPHGMLYNQAAKDPHLAQAIAKAVHDYDPSLILVGLAGSELIRAGERHRLVTRQEVF
                     ADRGYQADGSLVPRMQPGALIHDEEQALAQTLDMVQAGRVKSVTGVWTTVTAQTVCIH
                     GDGEYALAFARRLRAAFNARNVHVIA"
     gene            complement(803..1735)
                     /locus_tag="OPV72_002861"
     CDS             complement(803..1735)
                     /locus_tag="OPV72_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-dependent carboxyltransferase family
                     protein"
                     /protein_id="HCR9915107.1"
                     /translation="MLNIIRAGIYTSVQDSGRHGFRQSGLSHCGALDKPAFQTANLLV
                     GNDANAPALEITLGQLVVEFENETWFALTGAGCEAQLDDQPVWTGWRLPVKAGQRLTL
                     HRPLHGMRSYLAVAGGIAVPEVMGSCSTDLKSGIGGLEGRLLKDGDRLATGKPSRQLS
                     GPQGVKQLLWGNRIRALPGPEYREFDRASQEAFWRSPWQLSPQSNRMGYRLQGQSLTR
                     TTDRELLSHGLLPGVVQVPYNGQPIVLMNDAQTTGGYPRIACIIEADMYHLAQIPLEQ
                     PIHFVQCSLEEALNARRERRRYLEQLTWRLQHEH"
     gene            complement(1729..2385)
                     /gene="pxpB"
                     /locus_tag="OPV72_002862"
     CDS             complement(1729..2385)
                     /gene="pxpB"
                     /locus_tag="OPV72_002862"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HCR9915108.1"
                     /translation="MQRARCYLLGETAVVLELEPPITLASQKRIWRLTQRLVDMPNVV
                     EAIPGMNNITVILREPQTLALDAIERLQRWWEESEALEPDSRSVEIPVIYGGAGGPDL
                     AAVARHSGLSEKQVVELHASVEYVVWFLGFQPGFPYLGNLPEPLHMPRRAEPRLQVPA
                     GSVGIGGAQTGIYPLSTPGGWQLIGLTPLKLFDPMRETPVLLRPGDSVRFVPQKEGIC
                     "
     gene            complement(2401..3144)
                     /gene="ybgI"
                     /locus_tag="OPV72_002863"
     CDS             complement(2401..3144)
                     /gene="ybgI"
                     /locus_tag="OPV72_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radiation resistance protein YbgI"
                     /protein_id="HCR9915109.1"
                     /translation="MKNTELEQLINDKLNSAAISDYAPNGLQVEGKETVQKIVTGVTA
                     SQALLDEAVRLQADAVIVHHGYFWKGESPVIRGMKRRRLKTLLANDINLYGWHLPLDA
                     HPELGNNAQLAALLGITVKGEIEPLVPWGELSMPVPGLELASWIEARLGRKPLWCGDT
                     GPENVQRVAWCTGGGQSFIDSAARFGVDAFITGEVSEQTIHSAREQGLHFYAAGHHAT
                     ERGGIRALSEWLNENTALDVTFIDIPNPA"
     gene            3473..4954
                     /locus_tag="OPV72_002864"
     CDS             3473..4954
                     /locus_tag="OPV72_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR9915110.1"
                     /translation="MNKQASQPRAIYYVVALQIWEYFSFYGMRALLILYLTNQLKYDD
                     NHAYELFSAYCSLVYVTPILGGYLADKVLGNRMAVMLGAFLMAIGHLVLGASEIAPTF
                     LYLSLAIIVCGYGLFKSNISCLLGELYQPEDPRRDGGFSLLYAAGNIGSIVAPIACGY
                     VQEEYSWAMGFALAAIGMLAGLVIFLCGNRHFTHTTGVNKAVLCARNYLLPNWGWLLI
                     LLVAAPLLITVLFWKEWSVYALIVATAIGLVVLAKIYRQAQTAKQRKELGLIVTLTLF
                     SMLFWAFAQQGGSSISLYIDRFVNRDILGYSVPTAMFQSVNAFAVMLCGVVLAWLVKE
                     SVSGNRTVRIWGKFALGLGLMSAGFCILTLSARWSAAYGHSSMPLMVLGLAVMGFAEL
                     FIDPVAMSQITRIDIPGVTGVLTGIYMLLSGAIANYLAGVIADQTSQSAFDASGAVNY
                     AINAYVDVFEQITWGALACVGVVLLIWLYQSFKFKSRALAVES"
     gene            complement(4993..6414)
                     /gene="phrB"
                     /locus_tag="OPV72_002865"
     CDS             complement(4993..6414)
                     /gene="phrB"
                     /locus_tag="OPV72_002865"
                     /EC_number="4.1.99.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="HCR9915111.1"
                     /translation="MPTHLVWFRRDLRLQDNLALAAACRDASARVLALYISTPAQWQA
                     HDMAPRQAAFISAQLNALQTALAEKGIPLLFHEVADFNASIETVKNVCRQHDVSHLFY
                     NYQYEFNERQRDAAVEKTLPSVICEGFDDSVILAPGAVMTGNHEMYKVFTPFKNAWLK
                     RLKEDIPPCVPAPKIRVSGALSIPLTPVSLNYPQQAFDAALFPVEENAVIAQLRHFCS
                     QGADEYASRRDFPAVDGTSRLSASLATGGLSPRQCLHRLLAEQPQALDGGPGSVWLNE
                     LIWREFYRHLMTWYPALCKHQPFIRWTKRVAWQENPHYFQAWQKGETGYPIVDAAMRQ
                     LNATGWMHNRLRMITASFLVKDLLIDWRLGERYFMSQLIDGDLAANNGGWQWAASTGT
                     DAAPYFRIFNPTTQRERFDRDGEFIRQWLPALRDIPGKAIHEPWRWAEKAGVVLDYPR
                     PIVEHKQARIATLSAYEAARKGA"
     gene            complement(6525..6731)
                     /locus_tag="OPV72_002866"
     CDS             complement(6525..6731)
                     /locus_tag="OPV72_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbfA family protein"
                     /protein_id="HCR9915112.1"
                     /translation="MEHYKDYPAHVIFARRAFAVTAGVLALPVMLFWKDRARFYSYLH
                     RVWSKTSDKPVWMAQAEKATCDFY"
     gene            7068..7157
                     /gene="kdpF"
                     /locus_tag="OPV72_002867"
     CDS             7068..7157
                     /gene="kdpF"
                     /locus_tag="OPV72_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit F"
                     /protein_id="HCR9915113.1"
                     /translation="MSAGVITGIVLVFLLLGYLVYALINAEAF"
     gene            7157..8836
                     /gene="kdpA"
                     /locus_tag="OPV72_002868"
     CDS             7157..8836
                     /gene="kdpA"
                     /locus_tag="OPV72_002868"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpA"
                     /protein_id="HCR9915114.1"
                     /translation="MAAQGFLLIASFLLILLVLAKPLGSGLARLIAAVPLPGVAGVER
                     ILWRTLGITDHEMNWRQYLLALLTLNLLGLGILFCLLFWQEWLPLNPQRLPGLSWDLA
                     LNTAVSFVTNTNWQAYSGESTLSYFSQMAGLTVQNFLSAATGIAVVFALIRAFTRQNV
                     HTLGNAWQDLVRITLWILFPVALIIALFFIQQGVPQNLSAYQPITTLEGAKQLLPMGP
                     VASQEAIKMLGTNGGGFFNANSSHPFENPTALTNLAQMLAIFLIPAALCFAFGEAAGD
                     RRQGRALLWAMSFIFVVCVAVVMWAEVQGNPHLLAAGADSSVNMEGKEARFGVLASSL
                     FAVVTTAASCGAVNAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMLLFVLLAVF
                     IAGLMIGRTPEYLGKKIDVREMKMTALAILVTPMLVLLGSALAMMTDAGRSAMLNPGP
                     HGFSEVLYAVSSAANNNGSAFAGLSANSPFWNCLLAFCMFVGRFGVIIPVMAIAGSLV
                     SKKVQPASQGTLATHGALFIGLLIGTVLLVGALTFIPALALGPVAEHFSLP"
     gene            8857..10566
                     /gene="kdpB"
                     /locus_tag="OPV72_002869"
     CDS             8857..10566
                     /gene="kdpB"
                     /locus_tag="OPV72_002869"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpB"
                     /protein_id="HCR9915115.1"
                     /translation="MSRKQLALFEPVLLVQALTDAVKKLSPRAQWRNPVMFVVWAGSV
                     LATLLTLAMVTGQIAGSALFTGVISLWLWFTVLFANFAEALAEGRSKAQANSLKGVKK
                     TAFARRLRAPRHDAQADNVPAAELRKGDIVLVKAGDIIPCDGEVIEGGASVDESAITG
                     ESAPVIRESGGDFASVTGGRAVEAAGDVDVLLLDKTGTITLGNRQASDFIPARGVDER
                     TLADAAQLASLADETPEGRSIVILAKQRFNLRERDVQSLHATFVPFTAQSRMSGINID
                     NRMIRKGSVDAIRRHVESNGGHFPADVEQNVENVARLGATPLVVVEGARVLGVIALKD
                     IVKGGIKERFAQLRKMGIKTVMITGDNRLTAAAIAAEAGVDDFLAEATPEAKLALIRQ
                     YQAEGRLVAMTGDGTNDAPALAQADVAVAMNSGTQAAKEAGNMVDLDSNPTKLIEVVH
                     IGKQMLMTRGSLTTFSIANDVAKYFAIIPAAFAATYPQLNALNVMGLHSPNSAILSAV
                     IFNALIIIFLIPLALKGVSYKPLSASAMLRRNLWIYGLGGLVVPFIGIKVIDVLLTLL
                     DLA"
     gene            10575..11159
                     /gene="kdpC"
                     /locus_tag="OPV72_002870"
     CDS             10575..11159
                     /gene="kdpC"
                     /locus_tag="OPV72_002870"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpC"
                     /protein_id="HCR9915116.1"
                     /translation="MIGLRPAFSTMLFLLLLTGGVYPLLTTALGQWWFPWQANGSLIH
                     KDNLIRGSALIGQSFTAAGYFHGRPSATADTPYNPLASGGSNLAASNPELDAQIQARV
                     AALRAANPQASSAVPVELTTASASGLDNNLTPGAAAWQIPRVAAARQLPVEQVAQLVA
                     EYTHRPLASFLGQPVVNIVELNLALDALQGHRAK"
     gene            11156..13840
                     /gene="kdpD"
                     /locus_tag="OPV72_002871"
     CDS             11156..13840
                     /gene="kdpD"
                     /locus_tag="OPV72_002871"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     KdpD"
                     /protein_id="HCR9915117.1"
                     /translation="MNDEPLRPDPDRLLEQTPPPHRGKLKIFFGACAGVGKTWAMLAQ
                     AQRLRAQGLDVVIGVVETHGRKETAALLDGLTILPPKRHSHRGRQIREFDLDAALARR
                     PALILMDELAHSNAPGSRHPKRWQDIEELLEAGIDVFTTVNVQHLESLNDVVSGVTGI
                     QVRETVPDPFFDAADEVVLVDLPPDDLRQRLNEGKVYIAGQAERAIEHFFRKGNLIAL
                     RELALRRTADRVDDQMRAWRAHPGEEKVWHTRDAILLCIGHNTGSEKLVRTAARLASR
                     LGSVWHAVYVETPTLHRLPEKQRRAILSALRLAQELGAETATLSDPAEEKAVVRYARE
                     HNLGKIVMGRPASRRWWRRDAFADRLARRAPDLDQVIVALEEPPARALAQTPDNRPFK
                     EKWRGQIQGCLVAVALCAITTFIAMQWLVTFDAANLVMLYLLGVVVIALLYGRWPSVV
                     ATVINVASFDLFFIAPRGTLAVSDVQYLLTFAVMLTVGLVIGNLTAGVRYQARVARYR
                     EQRTRHLYEMSKALAVGRSEHDIAATSERFIASTFQARSQILLPDTNGKLLPLTHQQG
                     MTPWDDAIARWSFDKGQPAGAGTDTLPGVPYQILPLKSADKTYGLAIVEPGNLRQLMV
                     PEQQRLLETFTLLVANALERLTLTASEEQARLASERESIRNALLAALSHDLRTPLTVL
                     FGQAEILTLDLASAGSPHARQASEIRQHILNTTRLVNNLLDMARIQSGGFNLKKEWLT
                     LEEVVGSALQMLEPGLLHPITLSLPQQLTLIHVDGPLFERVLINLLENAVKYAGPQAS
                     IGIDAAVKDNRLQLDVWDNGPGIPAGQEQKIFDKFARGNKESAVPGVGLGLAICHAIV
                     EVHGGTLTAYNRPQGGACFRVTLPQGKPPELDDFHEDM"
     gene            13837..>14488
                     /gene="kdpE"
                     /locus_tag="OPV72_002872"
     CDS             13837..>14488
                     /gene="kdpE"
                     /locus_tag="OPV72_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator KdpE"
                     /protein_id="HCR9915118.1"
                     /translation="MTNVLIVEDEQAIRRFLRAALEGDGLRVYEAETLQRGLLEAATR
                     KPDLIILDLGLPDGDGIDFIRDLRQWSAIPVIVLSARSEESDKIAALDAGADDYLSKP
                     FGIGELQARLRVALRRHAASPCADPIVRFSGVTVDLAARLIHRGDEEIHLTPIEFRLL
                     AVLLNNAGKVLTQRQLLNQVWGPNAVEHSHYLRIYMGHLRQKLEQDPTRPRHFIIET"
BASE COUNT         3010 a         4151 c         4063 g         3264 t
ORIGIN      
        1 tccctcttcc tgacattaag agaacagaac acgataattt ttagcagccg taatataata
       61 gcttcaatcg tcgggctctc aggcaataac gtgtacatta cgcgcattga acgcggcgcg
      121 tagcctgcgt gcgaatgcaa gcgcatactc gccgtcgcca tgaatgcaca ccgtttgcgc
      181 cgtgacagtc gtccacacgc cagtaacgct tttcactctc ccggcttgta ccatatccag
      241 cgtttgcgcc agcgcctgct cttcgtcgtg aatcagcgcg ccaggttgca tgcgcggcac
      301 caggctaccg tcggcctgat agccgcgatc ggcaaacacc tcctgccgcg tcaccaggcg
      361 atggcgttca ccggcccgga tcagctcact tcccgccagt ccaaccagta tcagtgacgg
      421 atcatagtcg tgtaccgctt tcgcaatcgc ctgtgccaga tggggatctt tcgccgcctg
      481 gttatagagc ataccgtgcg gtttgacatg gcgcatcacg ccgccttgcg cctgaacaat
      541 cgcccccagc gcgccgattt ggtacagcgt ctgggcgtat accgtttccg gcggcaaaac
      601 catcgccgtc cgcccaaaat tatcccgatc cggaaagctg ggatgcgcgc cgatcgccac
      661 gccgtttttc agcgcctcgc gcacgcaggt cagcatggtt tgcgcatcac cggcgtgaaa
      721 accacaggcg atattagcgg aggagaccag cgttaataat tcgctgtcgc tggcgcaacc
      781 ttcgcccaaa tccgcattta aatcaatgtt catgctgaag tcgccaggta agctgttcca
      841 gatagcgccg acgctcgcgg cgcgcgttga gcgcctcctc cagcgaacat tgcacaaaat
      901 ggatcggttg ttctagcggg atctgcgcca gatggtacat atctgcctcg atgatgcagg
      961 caatgcgcgg atagccgcca gttgtctggg catcattcat taacacaata ggttggccgt
     1021 tgtaaggcac ctgcacgaca ccgggcagca aaccgtgcga cagcagttcg cgatccgttg
     1081 tccgcgttaa cgattgtccc tgcaaacgat agcccatgcg attactttgc ggactgagct
     1141 gccacggcga acgccagaac gcttcttgcg aggcgcgatc gaactcacgg tattccggcc
     1201 ccggtagcgc acggatgcga ttcccccaca gtaactgctt cacgccctgc ggcccgctaa
     1261 gctgtcgcga tggtttaccc gtcgccagcc gatcgccatc ttttagcagc cgtccttcca
     1321 gcccaccgat gccggacttc agatcggtac tacacgatcc catcacctcc ggcacagcaa
     1381 taccgcccgc caccgccaga tagctacgca tcccgtgaag cggtcgatgc agcgtaagac
     1441 gctgacccgc ttttaccggc aatcgccagc cggtccagac cggttgatca tccaactgcg
     1501 cctcgcagcc tgcgccggta agagcgaacc aggtctcatt ttcaaattcg acaaccagtt
     1561 gaccgagagt gatttccagc gccggggcat tcgcatcgtt cccgaccagg agattagcgg
     1621 tctgaaaggc gggtttatcc agcgcaccgc agtgactcag ccccgactga cgaaagccgt
     1681 gacgcccgct atcctgcacg gaggtgtaaa tccccgcgcg aataatattc agcatattcc
     1741 ctccttttgc ggcacaaagc gtacgctatc gccagggcgt agcagaaccg gggtctcccg
     1801 catcggatcg aataacttca acggcgtgag gccgatcagc tgccagccgc ccggcgtgga
     1861 taatggataa atccccgtct gcgcgccgcc gatgccgaca gaaccggccg gaacctgcag
     1921 gcgcggctct gcgcgtctgg gcatatggag cggttctggt aaattcccaa gatagggaaa
     1981 gccgggctga aagcctaaaa accagacgac atactcaacg gaggcatgta gctccacgac
     2041 ctgcttttca ctcaaaccgc tgtgccgtgc caccgccgcc agatccggcc cgcctgcgcc
     2101 gccatagatc accgggatct caaccgaacg cgagtccggt tccagcgcct cgctctcttc
     2161 ccaccagcgc tgcagacgct caatcgcatc cagcgccaga gtttgcggtt cccgcaagat
     2221 cacggtgata ttgttcatcc cgggaatggc ttccaccacg ttcggcatat cgaccagacg
     2281 ctgcgtcaga cgccagatgc gtttctggct cgccagcgta atcggcggtt caagttccag
     2341 gacgaccgcc gtttcgccta acagataaca acgcgctcgc tgcactttat tacctctcag
     2401 ttatgccggg ttagggatat caataaacgt cacatccaac gccgtgtttt cgttcaacca
     2461 ttcgctcagg gcgcgaatac cgccgcgttc agtggcatgg tgcccggcgg cataaaaatg
     2521 cagcccctgt tcgcgtgcgg aatgaatggt ctgttcagac acctcgccgg taataaaagc
     2581 atccacgccg aagcgggcgg cgctatcaat aaaactttgt ccgccgccgg tacaccaggc
     2641 gacacgctgc acattctctg gcccggtatc gccgcaccat agcggtttac gccccagacg
     2701 cgcttcaatc catgaggcca gttccagccc cggcaccggc attgagagct ctccccacgg
     2761 caccagcggc tcaatttctc ctttcacggt aatgcccaat agcgccgcca actgcgcatt
     2821 gttgcccagc tcagggtgcg catccagcgg cagatgccaa ccgtaaaggt taatatcatt
     2881 tgccagtaac gtttttaagc gacggcgttt catgccgcga ataaccggag actcgccttt
     2941 ccagaagtaa ccatgatgaa caatgaccgc atcggcctgc aaacgcaccg cctcatcgag
     3001 cagcgcctga cttgcggtca cgccggtaac gattttctgt accgtctctt ttccttcgac
     3061 ctgtaaacca ttcggcgcat aatcgcttat tgccgcactg ttcagcttgt cgttaatcag
     3121 ttgttccagc tcggtgtttt tcatcatcgc tccctttaac ccacgttcta ctttcccgtt
     3181 acgggttcag tctccgttaa catagcctcc cgttagccgt tcgtcgataa acatttgttt
     3241 gacacatcaa gaaacaatca cccccgggtt tggcgcaaat tacttagcaa aacacgatcg
     3301 gtttcatgta tatttatgca atcagaacgc atattgcaga aaaaatcagt tctgtatcat
     3361 gttggtaact ttaaggaaac acggcgatac ggcaggctta ataagcccac aaagaaaggc
     3421 attatctgag aatgccgcgt tcttgccgca gcgtctctat cccggaaata cgatgaataa
     3481 acaagcatct caaccccgcg ctatttacta cgttgtcgcc ctgcaaattt gggagtactt
     3541 cagcttttat ggtatgcgcg ccctactgat tctttatctc accaatcagc taaaatacga
     3601 cgataaccac gcctatgagt tattcagcgc ttattgttcg ctggtctacg taacgccaat
     3661 tctcggcggc tatctggcgg ataaggtgct tggcaaccga atggcagtca tgctgggcgc
     3721 atttttaatg gctataggtc atttagtgct gggcgccagt gagatcgcgc cgacattcct
     3781 ttatctgtcg ctggcgatca ttgtctgcgg ctacggcctg tttaaatcga atattagctg
     3841 cctgctgggc gaactgtacc agccggaaga tccgcgccgc gacggcgggt tctcgctgct
     3901 ttacgcagcg ggcaatattg gttcgatcgt ggcgcctatc gcctgcggct atgtgcaaga
     3961 ggagtacagt tgggcgatgg gctttgcgct cgccgccatt ggtatgctgg cggggctggt
     4021 gatcttcctg tgtggaaatc gtcatttcac ccacactacc ggcgtgaata aagccgtgtt
     4081 gtgcgccaga aactacctgc tgccgaactg gggctggctg ttaattctgc tggtagcggc
     4141 gccgttgctg attaccgttc tgttctggaa agaatggtct gtctatgcct taatcgtggc
     4201 gaccgcgatc ggcctggtcg tgctggcaaa aatttatcgt caggcgcaaa cggccaaaca
     4261 acgcaaagaa ctggggctga ttgtcaccct gaccctgttc agtatgctgt tctgggcgtt
     4321 tgcccagcag ggcggcagtt ctatcagcct gtatatcgac cgctttgtga accgcgatat
     4381 tctgggctat tccgttccta ccgccatgtt ccagtcggtg aacgcctttg ccgtgatgct
     4441 gtgtggggtc gtcctggcct ggctggttaa agagagcgta agcggtaatc gcaccgtgcg
     4501 tatctggggc aaattcgcgc tgggtctcgg tctgatgagc gccggattct gtattctgac
     4561 cctgagcgca cgctggtccg ccgcttacgg acactcttca atgccgctaa tggtgctggg
     4621 actggcggtg atgggctttg ccgagctgtt tatcgacccg gtcgccatgt cgcaaattac
     4681 gcgcattgat atccccggcg tcaccggcgt attaaccgga atttatatgc tgctgtccgg
     4741 cgcgatagct aactatctgg caggcgtcat cgctgaccag acctcgcaaa gcgccttcga
     4801 cgccagcggc gcggttaatt acgccatcaa cgcctatgtg gatgtttttg aacagatcac
     4861 ctggggcgcg ttagcctgcg taggggttgt cctgctgatt tggctgtatc agtccttcaa
     4921 attcaaaagc cgcgcgctgg ccgtcgaatc ctgatagcag aaggcccggt agtttgcgct
     4981 accgggcctg tatcacgccc cttttctcgc cgcctcatag gcggaaagcg ttgcgattct
     5041 cgcctgtttg tgctccacaa taggccgagg ataatcaagt acgactcccg ctttttccgc
     5101 ccaccgccac ggctcgtgaa tcgcttttcc aggtatatcg cgtaatgccg gtagccactg
     5161 gcggataaat tcgccgtcgc gatcgaacct ctctctctga gtcgtgggat taaaaatacg
     5221 aaaataaggc gcggcatcgg taccggttga agcggcccac tgccagccgc cattattggc
     5281 ggcaagatcg ccgtcaataa gctgcgacat gaaatagcgc tcccccaacc gccagtcaat
     5341 tagcagatct tttaccagaa agctggcggt aatcatgcgt aaacggttat gcatccagcc
     5401 cgtcgcgtta agctggcgca tcgccgcatc gacaatggga taaccggttt cgcctttctg
     5461 ccatgcctga aaatagtgcg ggttctcctg ccacgcgacg cgttttgtcc agcggataaa
     5521 cggctggtgt ttgcataatg ccggatacca ggtcattaaa tgacggtaaa attcccgcca
     5581 gatgagctca ttcaaccaga cgcttcccgg cccgccgtcc agcgcctgcg gctgctccgc
     5641 cagtaatcgg tgcaggcact gtcgcggcga caggccaccc gtcgccaggc tggcggaaag
     5701 ccgactggtg ccgtcaaccg cagggaaatc gcgccgtgac gcatactcgt ctgcgccctg
     5761 cgagcaaaaa tgacgtagct gcgcgatgac cgcgttttct tccaccggga aaagcgcggc
     5821 gtcaaacgcc tgttgcgggt agttaagcga gactggcgtt aagggtatag aaagcgcgcc
     5881 gctcacccgg atcttcgggg ccggaacgca cggcgggata tcctctttta gccgtttcaa
     5941 ccaggcgttt ttaaacggcg taaaaacttt atacatttca tgattgccgg tcatcaccgc
     6001 gccgggcgcc agaatcacgc tatcgtcaaa gccttcgcag atgacagatg gcagcgtttt
     6061 ttccaccgcc gcatcacgct gacgctcgtt aaactcatac tgatagttat aaaacagatg
     6121 gctgacgtca tgctgccggc aaacgttttt aaccgtctca atactggcgt taaaatccgc
     6181 cacttcatga aacagcagcg gaatcccttt ctctgcaagg gccgtctgta gcgcattgag
     6241 ctgcgcgctg atgaatgccg cctgccgcgg cgccatatca tgggcctgcc actgggcggg
     6301 ggtggaaata taaagcgcca gcacccgcgc ggatgcatcg cggcaggcgg cggccagcgc
     6361 aaggttatcc tgtaaacgca gatcgcgcct gaaccagact aaatgggtgg gcatacaact
     6421 cctgaaagat gaaacgtcac ggcgaatagc gttaaacagt gtagaccctg gcgcataaaa
     6481 aaaccgccag cgtggcggct gacggttttt caggctggtc gcgattaata aaagtcgcag
     6541 gtggcttttt cagcctgcgc catccatacc ggtttatcac tggttttcga ccagacacgg
     6601 tgcagataac tataaaaacg cgcgcggtct ttccagaaga gcatcaccgg caacgccagc
     6661 acgcctgcgg tcaccgcgaa agcacgacgt gcaaaaatga catgcgctgg atagtcttta
     6721 tagtgttcca tacgtttccc ccctttatac cgacgctatc cgccccggta tagattgaat
     6781 cggtgaatag caccgaaaaa ttgaacctcg ttacctgatt aaaatagtac cgctttcggt
     6841 gtaatttcac tactcatccg accacttatt ttcacgcttt tccagcagat ttacattcaa
     6901 agcgtaaatt agttacaaaa aggttaaatt aatactaatc attagttaaa taatggtctt
     6961 tgccattttt atactttttt tacactccgc ccgccaattt ttgcgaaatc tttgcagcca
     7021 aaaaattacc tttctcagga gtaaaacaat gccactggag gtgctctgtg agtgcaggcg
     7081 tgataaccgg catcgtgctg gttttcttac ttttaggtta tctggtctat gccctgatta
     7141 atgcggaggc gttctgatgg ccgcgcaagg atttttactg atcgccagtt ttttactgat
     7201 tttattggta ctggcgaaac cgttgggttc gggcctggca aggctcatcg ccgccgttcc
     7261 gttgccgggc gtggctggcg ttgagcgtat cctctggcgg actcttggca ttaccgacca
     7321 cgaaatgaac tggcgtcagt atttactggc gctactgacg ctcaatctgc tgggactggg
     7381 catcctgttt tgcctgctat tctggcagga gtggctgccc ttaaatccgc agcggctacc
     7441 ggggctgtcc tgggatctgg cgctgaatac cgccgtcagc tttgtcacca ataccaactg
     7501 gcaagcctac agcggcgaaa gcacgctgag ctactttagc cagatggcgg ggctgacggt
     7561 gcaaaatttc ctgtcggcgg cgaccgggat tgcggtggtt tttgcactta tccgcgcctt
     7621 tacgcgccag aatgtgcaca cgctgggtaa tgcctggcag gatctggtac gcattacgct
     7681 atggatatta tttcctgtcg cgttaattat cgcgctgttt tttatccaac agggcgtacc
     7741 gcaaaacctg tcggcttatc agcccatcac cactcttgaa ggcgctaaac aactcttgcc
     7801 gatggggccg gttgcttcgc aggaggcgat caaaatgctt ggcaccaacg gcggaggttt
     7861 ctttaacgcc aactcttcgc atccgttcga aaatcccacc gcgctcacta atctggcgca
     7921 gatgctggcg atatttttga ttccagccgc gctctgtttc gcctttggcg aagcggcggg
     7981 cgatcgccgt cagggacgcg ccctactgtg ggcaatgtca ttcatttttg tggtctgcgt
     8041 agcggtagtg atgtgggcgg aagttcaggg aaatccacat ctgttggcgg caggcgcgga
     8101 cagtagcgtc aacatggaag gtaaagaggc acgctttggc gtgctggcca gcagcctgtt
     8161 tgccgtcgtc acgaccgcgg cgtcctgcgg ggcggtaaat gccatgcacg actcgtttac
     8221 cgctctgggc ggtatggtgc cgatgtggct gatgcaaatt ggcgaagtgg tctttggcgg
     8281 cgtcggttca gggctgtacg gcatgttgct gtttgtcctg ttggcggtgt ttatcgcggg
     8341 gctgatgatc ggtcgcacgc cggagtatct ggggaaaaaa atcgacgtgc gcgaaatgaa
     8401 aatgaccgcg ctggcgattc tggtcacgcc gatgctggtc ttgttgggtt cggcgctggc
     8461 gatgatgacg gatgccggac gcagcgcaat gctgaaccct ggcccgcacg gttttagcga
     8521 agtgctatat gccgtctcct ctgccgccaa caacaacggt agcgcctttg caggtctgag
     8581 cgctaactcg cctttctgga actgtttgct ggcgttctgc atgttcgtcg gacgtttcgg
     8641 cgtgattatt cctgtcatgg ccatcgccgg atcgctggtc agtaaaaaag tacagccggc
     8701 cagtcaggga acgctggcga cccacggcgc gctatttatt ggactgctca ttggcacggt
     8761 actgctggtc ggcgcgctga cgtttattcc tgccctggcg cttggcccgg tagcggaaca
     8821 tttctcttta ccttgagcga tgcggagtac attgatatga gtcgcaagca actggcgctg
     8881 tttgaacctg ttttactcgt acaggcgcta acggatgccg taaaaaaatt aagcccacgc
     8941 gcccagtggc gtaacccggt gatgtttgtg gtctgggccg gcagcgtgct agccactctg
     9001 ttaacgctcg ctatggtaac aggacaaata gcgggaagcg ccttgtttac aggggtgatc
     9061 agcctgtggt tatggttcac cgtactgttc gccaattttg ccgaagcact ggcggaaggc
     9121 cgcagcaaag cccaggcaaa cagtctgaaa ggggtgaaaa agaccgcgtt cgctcgccgt
     9181 ctgcgcgccc cgcgccatga tgcgcaggcc gataacgtgc ccgccgctga actgcggaaa
     9241 ggcgacattg tcctggtcaa agcgggcgat attattccct gcgacggcga ggtcatcgaa
     9301 ggcggcgcct cggtggatga aagtgcgatt accggcgaat ccgcgcccgt gatccgcgag
     9361 tccggcggcg atttcgcctc tgtcaccggc ggccgcgccg tagaagccgc gggcgatgtc
     9421 gacgtgttac tgctggataa aaccggcact atcacgctcg gcaaccgcca ggcgtccgat
     9481 tttatacccg cccgaggggt ggacgaacgc acgctggctg acgccgcgca gctcgcttcg
     9541 ctggccgacg aaacgccgga aggccgcagc attgtgatcc tcgccaaaca gcgctttaac
     9601 ctgcgtgaac gcgatgtgca gtcgcttcat gccacctttg ttccgtttac cgcgcaaagc
     9661 cgcatgagcg ggattaatat cgataaccgg atgatccgta aaggctcggt ggacgcgatt
     9721 cggcgtcatg tcgagagcaa tggcggccat tttcccgccg atgtcgagca aaacgtcgag
     9781 aacgtggcgc gtctgggcgc gacgccgctg gtggtcgtgg aaggcgcgcg cgtactgggt
     9841 gttatcgccc tcaaggatat cgttaaaggc ggcattaaag aacgtttcgc ccagctacga
     9901 aagatgggca ttaaaacggt gatgatcact ggcgataacc gcctgacggc ggcagcgatt
     9961 gccgccgaag ccggtgtgga cgattttctt gccgaagcca cgccggaagc caagctggcg
    10021 ttgatccgtc aatatcaggc ggaaggacgg ctggtcgcca tgaccggcga cggcactaac
    10081 gatgccccgg cgctggcgca ggctgacgtc gcggtggcga tgaactccgg cacccaggcg
    10141 gcgaaagaag ccggtaatat ggtggatctg gactctaacc cgaccaagtt gattgaagtg
    10201 gtgcatatcg gtaagcagat gctgatgacg cgcggctcgc tcaccacctt cagtatcgcg
    10261 aatgatgtag cgaaatattt cgccattatt cccgccgcgt ttgccgctac ctatccgcag
    10321 ctaaacgcgc tcaacgtgat ggggctgcat tcgccgaact ccgccattct gagcgcggtg
    10381 atctttaacg ccctgattat catatttctg atcccgctgg cattaaaagg cgtgagttat
    10441 aagccgcttt ccgcatcggc catgctgcgc cgtaatttat ggatctatgg tctgggtggt
    10501 ctggtggtgc cgtttattgg catcaaagtg attgatgtgc tgctgaccct gctggatctg
    10561 gcgtgaggtg tatgatgatc ggtttacgtc ctgctttttc gacaatgtta tttctgctgt
    10621 tattgaccgg cggcgtgtat ccgcttctga ccacggcgct ggggcagtgg tggtttccct
    10681 ggcaggctaa tggctcgctg attcataaag acaatctgat acgcggctca gcgcttatcg
    10741 gacaatcgtt taccgccgcg ggctattttc atggccggcc ctccgccacc gccgatacgc
    10801 cttataatcc actggcgtcg ggcggaagca acctggccgc cagcaatccc gaactggatg
    10861 cgcaaattca ggcccgcgtc gccgcgctac gcgccgctaa cccccaggcg agttccgcgg
    10921 ttccggttga gctgacgacg gcgtcggcaa gcgggctgga taataatctg acgcccggcg
    10981 ccgcggcatg gcaaatcccc cgcgtggcgg cggctcgcca gcttcccgtt gaacaggtcg
    11041 cgcaactggt tgcagaatat acgcacaggc cgctggcgag ctttcttggg caaccagtgg
    11101 tgaatattgt tgagcttaat ctggcgctgg atgcgctaca gggacacaga gcgaaatgaa
    11161 cgacgaaccc ttgcgtcctg atccggatcg cttgttggaa caaacgcccc cgccccaccg
    11221 ggggaagtta aaaattttct tcggcgcctg cgcaggcgtc ggaaaaacct gggcgatgct
    11281 ggcgcaagcg cagcggctgc gagcgcaggg gctggatgtg gtgatcggcg tggtagagac
    11341 gcacggccgt aaagagaccg ccgcgctact tgacgggctg accattctgc cgccaaaacg
    11401 tcactcgcac cgggggcggc aaattcgcga atttgacctg gatgccgccc tcgcccggcg
    11461 tccggcgctg attttaatgg atgagctggc gcacagtaac gcgcctggct cacgccatcc
    11521 taagcgctgg caggatattg aagagctgct ggaagcggga atcgacgttt tcaccaccgt
    11581 gaacgtacaa catctggaaa gtctgaatga tgtggtgagc ggcgtcacgg ggattcaggt
    11641 gcgcgagacc gtccccgatc ccttttttga tgccgctgat gaagtcgtac tggtcgatct
    11701 gccgcccgac gatctgcgcc aacggctcaa cgaaggtaaa gtgtatatcg ccggtcaggc
    11761 ggaacgcgct attgaacatt ttttccgcaa gggcaatctg atcgccctcc gcgagctggc
    11821 gctacgccgg acagccgatc gcgtggacga tcagatgcgc gcctggcgcg cgcatccggg
    11881 cgaagaaaaa gtatggcata cccgcgatgc gattttactg tgtatcgggc ataacactgg
    11941 cagcgaaaaa ctggtgcgta ccgcggcgcg tctggcctcc cggctcggca gcgtctggca
    12001 cgccgtctat gtcgaaacgc caacgttaca ccgcttaccg gaaaaacaac ggcgggctat
    12061 tttaagcgcg ctgcgcctgg cgcaggagct tggcgcggaa accgccaccc tgtccgatcc
    12121 cgccgaagag aaagcggtcg tgcgctatgc ccgcgagcat aatctgggga aaatcgtcat
    12181 gggccgcccg gcgtcgcgac gctggtggcg acgtgacgct ttcgccgacc gtcttgccag
    12241 gcgcgcgccg gatctcgatc aggtaatcgt cgcgctggaa gagccgccag cgcgcgcgtt
    12301 ggcgcaaacg cctgataacc gaccttttaa agagaaatgg cgtggacaga ttcagggctg
    12361 tctggtcgcc gtggcgcttt gcgccataac cacgtttatc gctatgcagt ggcttgtcac
    12421 cttcgacgcc gccaatctgg tgatgctcta tttgctgggc gtagtggtga ttgcgctgct
    12481 ttacggacgc tggccgtcgg tggtggcgac ggtgattaac gtggcgagtt tcgatctctt
    12541 ttttatcgca ccacgcggta cgctcgccgt ttcggacgtg cagtatttgc tgacctttgc
    12601 cgtgatgctg acggttggtc tggtgattgg caatcttact gccggggtgc gctatcaggc
    12661 gcgcgtcgcc cgttatcggg aacagcgtac ccgccattta tatgaaatgt ctaaagcgct
    12721 ggccgtcggg cgtagcgaac atgatatcgc cgcgaccagc gagcggttta tcgcctcgac
    12781 gtttcaggcg cgcagccaaa ttttattacc tgatactaac ggtaagttgc tgcctctcac
    12841 ccaccagcaa ggcatgacgc cgtgggacga cgcaattgcg cgctggagtt ttgataaagg
    12901 ccagcctgcc ggcgcaggca ccgataccct tcctggcgtg ccttatcaaa tcctgccgct
    12961 gaaaagcgcc gataaaacgt acggtctggc tatcgtcgaa ccgggtaatt tgcgtcagtt
    13021 aatggtgccg gagcagcaac gcctgctgga aacattcact ctgcttgtcg ccaacgcgct
    13081 ggaacgactg acgctgaccg ccagcgaaga acaggcgcgt ctcgccagcg agcgcgaaag
    13141 tattcgcaac gctctgctgg cggctctgtc gcatgattta cgcacgccgc tgacggtatt
    13201 gttcggccag gcggaaattt tgacgctgga tttagccagc gcaggatcgc cccacgcgcg
    13261 tcaggccagt gaaatccgcc agcatattct caacaccacc cggctggtga ataatttgct
    13321 ggatatggcg cgtattcagt ccggcgggtt taatcttaaa aaagagtggc tgacgctgga
    13381 agaggtcgtc ggtagcgcgt tacagatgtt agagccgggt ttattgcatc cgattacatt
    13441 gtcgctgccg caacagttaa cgcttatcca tgtcgatggc cccttatttg agcgtgtcct
    13501 gatcaacttg ctggaaaacg ccgttaagta cgccgggccg caggccagta tcggcattga
    13561 tgctgcggtt aaggacaatc gtttacaact ggatgtctgg gataatgggc cgggtattcc
    13621 tgcggggcaa gaacagaaga ttttcgataa gttcgcccgc ggcaacaaag agtccgccgt
    13681 ccccggcgtg gggctggggc tggcgatttg ccatgctatc gtagaggtac acggcggcac
    13741 gcttaccgcc tataatcgac cgcagggcgg cgcctgtttc cgtgtgacgc tgccgcaagg
    13801 aaagccacct gaacttgacg attttcatga ggatatgtga caaacgttct gattgttgaa
    13861 gatgaacagg ccatccgccg ctttctgcgc gccgcgctgg aaggcgacgg cctgcgcgtg
    13921 tatgaagctg aaacattaca acgtggttta ctggaagccg ccacgcgaaa gcccgatctg
    13981 attattctcg atctcggcct gccggacggc gacggaatcg attttattcg cgacctgcgt
    14041 cagtggagcg caataccggt gattgtcctt tccgcccgca gcgaagaaag cgataagatt
    14101 gccgcgcttg acgccggagc tgatgattac ctgagcaagc cattcggcat tggcgagttg
    14161 caggcgcgtt tgcgtgtcgc gctgcgacgg cacgccgcca gcccttgcgc cgatccgatc
    14221 gtccgctttt ccggcgtgac ggtcgatctc gccgcacggt tgatccaccg tggcgacgaa
    14281 gaaatccatc tgacgccgat tgagttccgc ctgctggcgg tattactcaa taatgccggc
    14341 aaggtattaa cccaacggca gttattaaac caggtctggg gccctaacgc cgtggagcat
    14401 agccactatt tgcgcatcta tatgggacat ttacgccaga aactggaaca agatcccacc
    14461 cgcccacgcc attttattat cgaaaccg
//
LOCUS       DAJVBX010000115        14457 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.115, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000115 DAJVBX010000000
VERSION     DAJVBX010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 14457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14457
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.115"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            71..238
                     /locus_tag="OPV72_002873"
     CDS             71..238
                     /locus_tag="OPV72_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006819399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="general stress protein"
                     /protein_id="HCR9915119.1"
                     /translation="MANHRGGSGNFAEDRERASEAGRKSGQHSGGNFKNDPQRASEAG
                     KKGGKSSNRNR"
     gene            375..1013
                     /gene="rutR"
                     /locus_tag="OPV72_002874"
     CDS             375..1013
                     /gene="rutR"
                     /locus_tag="OPV72_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator RutR"
                     /protein_id="HCR9915120.1"
                     /translation="MSQRTEKKIGKRSQATGAKRQLILTAALAVFSQYGIHGARLEQV
                     AERAGVSKTNLLYYYPSKEALYVAVMRQILDVWLAPLKAFRAEFSPLEAIKEYIRLKL
                     EVSRDYPQASRLFCMEMLAGAPLLMDELTGDLKALIDEKSALIAGWVHSGKLAPVSPH
                     HLIFMIWAATQHYADFAPQVEAVTGATLRDEAFFNQTVESVQRIIIEGIRVR"
     gene            complement(1010..1405)
                     /locus_tag="OPV72_002875"
     CDS             complement(1010..1405)
                     /locus_tag="OPV72_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme inhibitor LprI family protein"
                     /protein_id="HCR9915121.1"
                     /translation="MKRIFLTCAALLFSSQALADECASASTQLEMNRCAAAQYQAADK
                     KLNETYQSAIKRAQPPQRELLQKAQVAWIALRDADCALIRSGTEGGSVQPMIASQCLT
                     DKTNEREAFLASLLQCEEGDLSCPLPPAG"
     gene            complement(1464..5426)
                     /gene="putA"
                     /locus_tag="OPV72_002876"
     CDS             complement(1464..5426)
                     /gene="putA"
                     /locus_tag="OPV72_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_447555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trifunctional transcriptional regulator/proline
                     dehydrogenase/L-glutamate gamma-semialdehyde
                     dehydrogenase"
                     /protein_id="HCR9915122.1"
                     /translation="MGTTTMGVKLDDATRERIKMAASRIDRTPHWLIKQAIFSYLDKL
                     ENSDTLPELPALFAGAANESEEPVAPQDEPHQPFLEFAEQILPQSVSRAAITAAWRRP
                     ETDAVSMLMEQARLSPPVAEQAHKLAYQLAEKLRNQKSASGRAGMVQGLLQEFSLSSQ
                     EGVALMCLAEALLRIPDKATRDALIRDKISNGNWQSHIGRSPSLFVNAATWGLLFTGR
                     LVSTHNEANLSRSLNRIIGKSGEPLIRKGVDMAMRLMGEQFVTGETIAQALANARKLE
                     EKGFRYSYDMLGEAALTAADAQAYMVSYQQAIHAIGKASNGRGIYEGPGISIKLSALH
                     PRYSRAQYDRVMEELYPRLKSLTLLARQYDIGLNIDAEEADRLEISLDLLEKLCFEPE
                     LAGWNGIGFVIQAYQKRCPLVIDYLVDLASRSRRRLMIRLVKGAYWDSEIKRAQMEGL
                     EGYPVYTRKVYTDVSYLACAKKLLAVPNLIYPQFATHNAHTLAAIYHLAGQNYYPGQY
                     EFQCLHGMGEPLYEQVTGKVGDGKLNRPCRIYAPVGTHETLLAYLVRRLLENGANTSF
                     VNRIADATLPLDELVADPVEAVEKLAQQEGQAGIPHPKIPLPRDLYGEGRINSAGLDL
                     ANEHRLASLSSALLSNAMQKWQAKPVLEQPVADGEMTPVINPAEPKDIVGWGREATES
                     EVEQALQNAVNQAPVWFATPPQERAAILQRAAVLMEDQMQQLIGLLVREAGKTFSNAI
                     AEVREAVDFLHYYAGQVRDDFDNETHRPLGPVVCISPWNFPLAIFTGQIAAALAAGNS
                     VLAKPAEQTSLIAAQGIAILLEAGVPPGVVQLLPGRGETVGAQLTADARVRGVMFTGS
                     TEVATLLQRNIATRLDAQGRPIPLIAETGGMNAMIVDSSALTEQVVVDVLASAFDSAG
                     QRCSALRVLCLQDDIAEHTLKMLRGAMAECRMGNPGRLTTDIGPVIDSEAKANIERHI
                     QTMRAKGRPVFQAARENSDDAQEWQTGTFVMPTLIELENFAELEKEVFGPVLHVVRYN
                     RNQLAELIEQINASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVGAVVGVQPF
                     GGEGLSGTGPKAGGPLYLYRLLAHRPPNALNTTLTRQDARYPVDAQLKTTLLAPLTAL
                     TQWAADRPALQTLCRQFADLAQAGTQRLLPGPTGERNTWTLLPRERVLCLADDEQDAL
                     TQLAAVLAVGSQALWSDDAFHRDLAKRLPAAVAARVQFAKAETLMAQPFDAVIFHGDS
                     DKLRTVCEAVAAREGAIVSVQGFARGESNMLLERLYIERSLSVNTAAAGGNASLMTIG
                     "
     gene            5848..7356
                     /gene="putP"
                     /locus_tag="OPV72_002877"
     CDS             5848..7356
                     /gene="putP"
                     /locus_tag="OPV72_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/proline symporter PutP"
                     /protein_id="HCR9915123.1"
                     /translation="MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGP
                     FVTALSAGASDMSGWLLMGLPGAIFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTE
                     FNNNALTLPDYFTGRFEDKSRVLRIISALVILLFFTIYCASGIVAGARLFESTFGMSY
                     ETALWAGAAATIIYTFIGGFLAVSWTDTVQASLMIFALILTPVMVIVGVGGFSESLEV
                     IKQKSIENVDMLKGLNFVAIISLMGWGLGYFGQPHILARFMAADSHHSIVHARRISMT
                     WMILCLAGAVAVGFFGIAYFNNNPALAGAVNQNSERVFIELAQILFNPWIAGVLLSAI
                     LAAVMSTLSCQLLVCSSAITEDLYKAFLRKSASQQELVWVGRVMVLVVALIAIALAAN
                     PDNRVLGLVSYAWAGFGAAFGPVVLFSVMWSRMTRNGALAGMIIGAVTVIVWKQYGWL
                     DLYEIIPGFIFGSLGIVIFSLLGKAPTATMQERFAKADAHYHSAPPSKLQAE"
     gene            8249..9037
                     /gene="phoH"
                     /locus_tag="OPV72_002878"
     CDS             8249..9037
                     /gene="phoH"
                     /locus_tag="OPV72_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate starvation-inducible protein PhoH"
                     /protein_id="HCR9915124.1"
                     /translation="MGRQKAVIKARREAKRVLRRDSRSHKQREEESVTSLVQMGGVEA
                     IGMARDSRDTSPVKARNEAQAHYLNAIDSKQLIFATGEAGCGKTWISAAKAAEALIHK
                     DVERIIVTRPVLQADEDLGFLPGDIAEKFAPYFRPVYDVLLKRLGASFMQYCLRPEIG
                     KVEIAPFAYMRGRTFENAVVILDEAQNVTAAQMKMFLTRLGENVTVIVNGDITQCDLP
                     RGVRSGLSDALERFEEDEMVGIVHFNKDDCVRSALCQRTLHAYS"
     gene            complement(9143..10024)
                     /locus_tag="OPV72_002879"
     CDS             complement(9143..10024)
                     /locus_tag="OPV72_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCR9915125.1"
                     /translation="MEPQPPRLKPGKILDTLGAMQKSLTRASQRIAQYILAFPRQVTQ
                     SSIADLSRDTQAGEATVIRFCRTLGYKGFQDFKMDLAIELATTESDDSSPLLDAEVSE
                     SDDAHAIGLKLQNTISNVLSETLNLLDMQQVLGVVDALRHCHSVYIFGVGSSGITALD
                     MKHKLMRIGLRGDAVSNNHFMYMQATLLKAGDVAMGVSHSGTSPETVHSLRLARQAGA
                     TTVAITHNLGSPLCEEADFCLINGNRQGMLQGDSIGTKAAQLFVFDLLYTLLVQSSPE
                     QARESKLRTMNALDMTK"
     gene            complement(10310..11807)
                     /locus_tag="OPV72_002880"
                     /pseudo
     CDS             complement(10310..11807)
                     /locus_tag="OPV72_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460100.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
     gene            complement(12144..12824)
                     /locus_tag="OPV72_002881"
     CDS             complement(12144..12824)
                     /locus_tag="OPV72_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HCR9915126.1"
                     /translation="MSLLARLEQSVHENGGLIVSCQPVPGSPMDKPEIVAAMAQAAAS
                     AGAVAVRIEGIENLRTVRPHLSVPIIGIIKRDLTGSPVRITPYLQDVDALAQAGADII
                     AFDASFRSRPVDIDSLLTRIRLHGLLAMADCSTVNEGISCHQKGIEFIGTTLSGYTGP
                     ITPVEPDLAMVTQLSHAGCRVIAEGRYNTPALAANAIEHGAWAVTVGSAITRIEHICQ
                     WFSHAVKR"
     gene            13331..>14457
                     /locus_tag="OPV72_002882"
     CDS             13331..>14457
                     /locus_tag="OPV72_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate epimerase"
                     /protein_id="HCR9915127.1"
                     /translation="MGMQMKNFKKMMTLMALCLSVAITTSGYATTLPDIPEPLKNGTG
                     AIDNNGVIYVGLGTAGTSWYKIDLKKQHKDWERIKSFPGGAREQSVSVFLNDKLYVFG
                     GVGKKNSESPLQVYSDVYKYSPVKNTWQKVDTISPVGLTGHTGVKLNETMVLITGGVN
                     EHIFDKYFIDIAAADESEKNKVIYNYFNKPAKDYFFNKIVFIYNAKENTWKNAGELPG
                     AGTAGSSSVMENNFLMLINGELKPGLRTDVIYRAMWDNDKLTWLKNSQLPPSPGEQQQ
                     EGLAGAFSGYSHGVLLVGGGANFPGAKQNYTNGKFYSHEGINKKWRDEVYGLINGHWQ
                     YMGKMKQPLGYGVSVSYGDEVFLIGGENAKGKPVSSVTSFT"
BASE COUNT         3533 a         3560 c         3798 g         3566 t
ORIGIN      
        1 atacgcggcg cgaggagata ctcctcatta cctatgcaat atgatgtcta atctatgacg
       61 gaggtcagta atggcaaacc atcgtggcgg ttccggtaat tttgcggaag accgcgaaag
      121 agcatcagaa gcaggtcgta aaagtggtca gcacagcggg ggcaatttta agaatgaccc
      181 gcagcgtgca tccgaagcag gcaaaaaagg gggcaaaagc agtaaccgta atcgctagcc
      241 tgcgtcacaa cagcaagacg ctgagcgttt cgcgctaaaa agcgtcatgc gccaccgccg
      301 ccggatttcc ggcggttttt ttgtttataa gccggatttg gtatgcttgc gtcctgacga
      361 aaaggagagg gcgcatgtcg caacgcacag agaaaaaaat cgggaaacgt tcgcaggcca
      421 ccggtgcaaa acggcagctt atcttaaccg ccgcgcttgc cgttttttcc cagtatggca
      481 ttcatggcgc gcgtcttgaa caggtcgccg agcgggcagg cgtctccaaa accaatctgc
      541 tttattatta tccctcgaaa gaggcgctgt atgtcgcggt aatgcgacag attctggatg
      601 tctggttggc gccgctcaag gcgtttcgcg cagaattttc ccctctggag gccatcaaag
      661 agtatatccg tctcaagctg gaggtttcgc gtgattatcc gcaggcgtcg cggctcttct
      721 gcatggagat gctggcgggc gcgccgctct taatggatga actgaccggc gatctaaaag
      781 cgttgataga tgaaaaatcc gcgctgattg ccggatgggt gcacagcggg aaactcgcgc
      841 ccgtttctcc gcatcatttg atcttcatga tttgggccgc cacgcaacat tacgccgatt
      901 tcgcccctca ggttgaagcg gtaaccggcg cgacgcttcg cgatgaagcc tttttcaacc
      961 aaacggtcga aagcgttcag cgcattatta ttgaagggat tcgcgtgcgt taaccggctg
     1021 gcggcagtgg gcagctcaaa tcaccctctt cacattgcag cagcgaggct aaaaacgctt
     1081 cgcgttcgtt cgttttatcg gtcaggcact ggctggcgat catgggttga acgctgccgc
     1141 cctccgtacc tgagcgaatc agcgcgcaat cggcgtcgcg cagggcaatc catgccacct
     1201 gcgctttttg caatagctca cgctgcggcg gttgcgcacg cttaatcgcg ctttgatagg
     1261 tttcgttcag ctttttatct gccgcctggt attgcgcggc ggcgcagcga ttcatttcca
     1321 gctgcgtact ggcgctggca cactcatcgg ccaacgcctg actgctgaac aacaacgccg
     1381 cgcaggtaag gaaaattcgt ttcatacggt cctctgacgc gagtaaaaag gctccattga
     1441 cggagcctta attaaccaca gtattagcca attgtcatca ggctggcatt accgccagcg
     1501 gcggcagtgt ttacgctcag cgaacgttca atatagagcc gttccagcag catattgctt
     1561 tcgccgcggg cgaacccctg taccgacact atcgcgcctt cgcgggcggc gacggcttcg
     1621 cacacggttc gcagcttgtc ggagtcgccg tggaaaatca ccgcgtcaaa cggctgcgcc
     1681 atcagcgttt ccgctttcgc aaactggaca cgcgccgcga cggcggcggg gagacgtttc
     1741 gccagatcgc ggtggaaggc gtcgtctgac catagcgcct gactgccgac ggcgagaacg
     1801 gcggcaagct gcgtcaacgc gtcctgttca tcatcagcca ggcataacac ccgttcacgc
     1861 ggcaacagcg tccaggtatt acgctcgccg gtcggccccg gtagcaggcg ctgcgtgccg
     1921 gcctgcgcca gatcggcgaa ttgtcggcag agcgtctgta gcgccgggcg atccgccgcc
     1981 cattgcgtca gagcggtcaa cggcgcgagt agcgtggttt taagctgcgc atccaccggg
     2041 taacgcgcat cctgacgagt cagcgtcgta ttgagcgcat tgggcgggcg gtgtgccagc
     2101 aggcggtaga gatagagcgg ccctcccgct tttggcccgg tgccggacag gccttcgccg
     2161 ccaaacggct ggacgccgac gaccgcgccc accatattac ggttaacgta caggttgccg
     2221 acatgggcgg aaccggtgac ttgcgcaatg gtttcatcaa tacgggtatg tacgcccagc
     2281 gttagcccgt agccggaagc gttaatctgt tcgataagct ccgccagttg gttacggtta
     2341 taacgcacga cgtgcagcac gggcccgaag acctcttttt ccagttctgc gaagttttcc
     2401 agctcaataa gcgtgggcat aacaaacgta ccggtctgcc attcctgcgc gtcatcgctg
     2461 ttttcacgcg cggcctggaa aaccgggcgg cctttggcgc gcatcgtctg gatatgacgt
     2521 tcaatgttgg ctttggcctc gctatcgatc accggcccga tatcggtcgt cagacggcct
     2581 ggattcccca tccgacactc cgccatcgcg ccgcgtaaca ttttcagcgt atgttcggcg
     2641 atatcgtcct gcaaacacag cacgcggagc gcggaacagc gttgtccggc gctgtcgaag
     2701 gcggaagcca gcacatccac gaccacctgc tcggtgagcg cggaagagtc gacaatcata
     2761 gcgttcatac cgccggtttc cgcaatcaac ggaatagggc gcccctgggc gtcaagacgc
     2821 gtggcgatgt tgcgctgcaa caacgtcgcg acctccgtgg aaccggtaaa catcacgccg
     2881 cgtacacgcg catcggcggt aagctgggcg ccgacggttt ctccccgtcc cggcaacagt
     2941 tgcacgacgc ccggcggtac gcccgcttcc agcaaaatgg caatgccctg ggcggcaatc
     3001 agcgatgtct gctctgccgg tttcgccaga acgctgttac ctgccgccag cgcggcggcg
     3061 atttggccag tgaaaatggc cagcggaaag ttccacggac tgatacagac caccggccct
     3121 aacgggcgat gcgtttcgtt atcgaaatcg tcacgcactt gaccggcata ataatggagg
     3181 aagtctaccg cttcgcgcac ttcggcaatg gcgttgctga acgttttccc cgcttcacgc
     3241 accaacaggc caatcaactg ctgcatttgg tcttccatca ataccgccgc ccgctgcaaa
     3301 atagcggcgc gttcttgcgg cggcgtcgca aaccaaaccg gcgcctgatt gaccgcgttt
     3361 tgcaacgcct gttcaacctc gctttctgtc gcttcgcgtc cccagccaac aatatctttc
     3421 ggttccgccg ggttgataac cggcgtcatc tcaccgtcgg ccaccggttg ttccagcaca
     3481 ggtttggcct gccatttctg catggcgttg cttaacaggg cagaagaaag cgaggcgagg
     3541 cgatgttcat tcgctaaatc aagtccggcg gagtttatcc gaccttcgcc gtacagatcg
     3601 cgcggcagcg gaatttttgg atgcggtatg ccagcctgac cttcctgctg cgccagtttt
     3661 tccacggcct cgaccgggtc ggccaccagt tcatcgagcg gtagggtggc atcggcgatg
     3721 cggttgacaa aagaggtgtt ggcgccgttt tccagcaggc gtcgtaccag ataggccagc
     3781 agggtttcgt gtgttcccac cggcgcgtaa atacggcagg gacggttaag ttttccgtcc
     3841 cccactttac cggtgacctg ttcatacagc ggttctccca tgccgtgcag gcactggaat
     3901 tcgtactgac ccggatagta attttgcccg gccagatgat aaatcgccgc cagtgtgtga
     3961 gcgttatggg tcgcgaactg cgggtagatc agattaggga cggcgagcag ttttttcgcg
     4021 caggccagat aagagacatc ggtatacact ttgcgggtat aaactggata gccctccagc
     4081 ccttccattt gcgcgcgttt gatctcgcta tcccagtagg cgcctttcac cagacgaatc
     4141 atcagccgac ggcggctacg ggaggccaga tcgactaaat aatcaatgac cagcgggcag
     4201 cgtttctggt aagcctgaat cacaaagcca atgccgttcc agcccgccag ttcgggttcg
     4261 aagcagagtt tttccagcag atcaagcgag atctccagac gatccgcctc ttcggcgtcg
     4321 atattgagac cgatatcata ctggcgcgcc agcagcgtca gggatttcag gcgcggataa
     4381 agctcctcca ttacccgatc gtattgcgcg cgactatagc gtggatgcag ggcggacagc
     4441 ttaatcgaga tgcctggccc ttcgtaaata ccgcgaccgt tagacgcttt gccgatggca
     4501 tgaatcgctt gctggtaaga gaccatatag gcctgcgcat cggcggcggt taacgcggct
     4561 tcgcccagca tatcgtaaga atagcggaac cctttctctt ccagttttcg ggcattcgcc
     4621 agcgcctgag caatggtttc gccagtcacg aactgctcgc ccattaaacg catcgccatg
     4681 tcgacgcctt tgcggattaa cggttcgccg ctcttgccga taatgcggtt cagcgagcgc
     4741 gaaagattgg cttcgttatg cgttgagacc agtcggccgg taaagagcag cccccaggtg
     4801 gcggcgttta caaacagcga cgggctacgg ccaatatgcg actgccagtt gccattactg
     4861 attttgtcgc gaattaacgc atcgcgcgta gctttgtcgg gaatacgcag cagcgcttcc
     4921 gccagacaca tcagcgctac gccttcttgc gaagagaggg aaaactcctg caacaggcct
     4981 tgcaccatac ccgcgcgacc gctggcggat ttttgattgc gcaatttctc cgccagttga
     5041 tacgccagtt tatgcgcctg ctcagcgaca ggcggcgaca ggcgcgcctg ttccattagc
     5101 attgacaccg catcggtttc cgggcggcgc caggcggcgg tgatggcggc gcgagagacg
     5161 gattggggaa gaatctgttc ggcaaactcc agaaagggct gatgcggctc atcctgcggc
     5221 gcgaccggct cctcgctttc atttgccgcg ccggcaaaca gcgcaggtag ctccggtagc
     5281 gtatcgctat tttccagctt gtccagatag ctaaagattg cctgttttat taaccagtgc
     5341 ggcgtgcgat cgatacgcga cgcggccatt ttgatccgtt cgcgcgtggc gtcgtccagc
     5401 ttaaccccca tcgtggtggt tcccataccc tctactcctg ttattcgctc tatctgctaa
     5461 ccaatagtta gcggaaaata tccactatat tgcaactttg tgcaaccgcg ttaaatgtga
     5521 cctgcgttgc aagcttaaaa atgaataaat tgttaaaaaa agaaagtggg agtctgacgg
     5581 ggaaaaccat ctggatttat tttctctgcg gtagttaaca cttttaaaag gtgcaaccgc
     5641 aaaaaatgtg agagagtgca acctggagaa aaatagtatc cctctgcaat caaatttgat
     5701 gtaaatggtg tgttaaatcg attgtgaata accaccgatt ccggcaggat acggtcgccc
     5761 tggtaaacat aacacccttg ccacgttccg gcagggtaca aaacggcacg ctacggtagt
     5821 gccaataaat aaatttggag aaccttgatg gctattagca caccgatgtt ggtgacattc
     5881 tgtgtctata tttttggcat gatattgatt gggtttatcg cctggcgctc aaccaaaaac
     5941 tttgatgact atattcttgg cggtcgcagc ctggggccgt ttgttacggc tttatcagcc
     6001 ggcgcgtcgg atatgagcgg ctggctgtta atggggctgc ctggcgctat ctttctgtcg
     6061 gggatctctg aaagctggat cgccattggc ctgacgttag gcgcatggat taactggaag
     6121 ctggtggccg ggcgcctgcg cgtgcatacc gaatttaaca ataacgcgct cacgctgccg
     6181 gactatttta ccggtcggtt tgaggataag agccgagtcc tgcgtattat ttccgcgctg
     6241 gtcattctgc tgtttttcac tatctattgc gcatcaggta ttgtcgctgg ggcacgactg
     6301 ttcgaaagca ccttcggtat gagctatgaa accgcactgt gggcgggggc cgcggcaacc
     6361 attatttata cctttatcgg cgggtttctt gccgttagct ggacggatac cgttcaggcc
     6421 agcctgatga tttttgcgtt aatcctgacg ccggtgatgg ttattgtcgg cgtaggcggt
     6481 tttagcgagt cgctggaagt gatcaagcaa aagagcatcg agaatgtcga catgctcaag
     6541 gggctgaatt ttgtcgctat tatttctctg atgggctggg ggctgggtta cttcggtcag
     6601 ccgcatatcc tggcgcgctt tatggcggcg gattcccatc acagtattgt tcatgcgcgt
     6661 cgtatcagta tgacctggat gattctgtgt ctggcgggcg cggtggcggt gggcttcttt
     6721 ggcattgcgt actttaacaa taaccccgcg ctggccgggg cggtgaacca aaactcagaa
     6781 cgcgtattta ttgaactggc gcagatcctg tttaacccgt ggattgccgg tgttctgctg
     6841 tctgctatcc tggcggcggt gatgtcgacg ttgagctgtc agttgctggt atgctccagc
     6901 gcgattacgg aagatttata taaggctttt ctgcgtaaaa gcgccagcca gcaagagctg
     6961 gtatgggtag ggcgagtgat ggtgctggtg gtagcgctga tcgccattgc gctggcggcg
     7021 aatcctgata accgtgtgct ggggctggtg agctacgcct gggctggatt cggcgcggca
     7081 tttggacctg ttgtcctgtt ttctgtgatg tggtcgcgta tgacacgtaa cggcgcgctg
     7141 gcgggaatga ttattggcgc ggtgacggtt atcgtctgga aacaatatgg ctggctggat
     7201 ctgtatgaga ttatccctgg cttcattttc ggcagcctgg ggatcgtaat ctttagcctg
     7261 cttggcaaag cgccgacagc aacgatgcag gaacgctttg caaaagcgga cgcgcattat
     7321 cattccgcgc cgccgtcgaa gctacaggcg gaataaccga catgtccgat agcattattg
     7381 ccatcggata tattttacca ggcggcgtta tacgcctgcc tggtcctctg ataagtcccg
     7441 gaccgattga ctgaaggtgt tcaggtaaat gaggacgctc tctcaaacta tttttagccc
     7501 ttgagcgccg ttaacgcggc cgtaatacgt ctcgagtaat cactaactga ccatatatga
     7561 aatcgcctgt taatggtacc aatagccttg acgcaataga gtaatgacaa aaattaaaac
     7621 gagtcagcgt tactggcgta agtatgccgc acaaaatttt gcataaataa tgccgtttta
     7681 gcgatgggag agaggacacg ttaattactc cgttttaatc ttttatatgt tgaatattca
     7741 atgggttatg ggtgttttca ccattaatac ccatagtagc taatgattat cttttttagt
     7801 ctcctgccaa tgaaataatt gtgtaatctt tctgtaagag actgacaatg acgcaataat
     7861 gtttggttaa tgtttggtga atatattgtt gcattattga tgttttgtgt tgtacttagt
     7921 agtaatagcg gtagttcccc ggcagtgatg gtcactcact atggagatcg cgaatggtaa
     7981 tgtccgcacc aggacacatt gtttacagta gttacaacac cctgtacgga cattctctct
     8041 ccggtggtgg tcttgtcatc ttaaaagctc tcatcatttc ccttactgtc catacccatg
     8101 acgccatatg tggtgcgcgt agccgtgtgt ggcgtcgttt caaaaagcaa gctaaggctt
     8161 acaaggaagc caaccctcag atgtgtgtgc gcataatcgc gttcaagaga acgcgggtga
     8221 tgtataccta caactcaagg tgctatccat gggaagacaa aaagcagtga tcaaagctcg
     8281 tcgtgaagca aagcgtgtgt tgagacgaga ttcgcgtagt cataagcaac gtgaagaaga
     8341 atcggtcacg tcactggtac agatgggcgg agtagaagcc attggcatgg cgcgcgatag
     8401 tcgcgatacc tctcctgtta aggcgcgaaa tgaagcacag gcgcattatc tgaacgctat
     8461 cgacagtaaa cagcttattt ttgcgaccgg cgaagccggc tgcggaaaaa catggatcag
     8521 tgcggcaaag gcggcagaag cattgattca taaggacgtc gagaggatca ttgtgacgcg
     8581 tccggtattg caggctgatg aagatcttgg ttttttgccc ggtgatatcg ctgaaaaatt
     8641 cgcgccttat tttcgtcccg tctacgatgt cctgcttaaa cggttgggcg cgtcctttat
     8701 gcaatattgt ttgcgcccgg aaatcggtaa ggtagaaatt gccccgttcg cctatatgcg
     8761 tgggcgtact tttgaaaatg cggtcgtgat cctcgacgag gcgcaaaatg tgactgcggc
     8821 gcaaatgaaa atgtttttga cgcgattagg cgaaaatgtc acggtcattg tcaatggcga
     8881 tattacgcaa tgcgacctgc cgcgcggtgt gcgttccggg ttgagtgatg cgttggaacg
     8941 ctttgaagaa gatgaaatgg tggggattgt gcatttcaac aaagacgact gcgtgcgctc
     9001 ggcgctttgt cagcgaacgc tccacgcata cagctaatat agcattgact ttcagagccc
     9061 gggagaccgg gctttgttgt ctataaagcg tccagcagac tcatggacaa aaaaggaaaa
     9121 tgacgcctgt acgtgaaggg aattattttg tcatgtccag ggcattcatt gtccgtaatt
     9181 tgctttctcg ggcctgttcc ggcgaggact gtacaagaag ggtatagagc aggtcaaaga
     9241 cgaaaagctg cgcggctttc gtaccgatcg agtcaccctg caacattcct tgccgattac
     9301 cattgatcag gcaaaaatcg gcctcttcac ataatggaga acccagatta tgggtaatgg
     9361 cgactgtggt ggcgccagcc tgtcgggcca atcggagtga atgcactgtt tctggcgatg
     9421 tgcccgagtg actgacaccc atcgcgacat cgcctgcttt taatagcgta gcctgcatgt
     9481 acataaaatg gttattgctt accgcatcgc cccgtaaacc aatacgcatt agcttgtgtt
     9541 tcatatccag cgccgtgatc cccgatgagc ccacaccaaa gatataaact gagtgacagt
     9601 gacgtagggc gtccacgaca ccgagaacct gttgcatatc aagcagattt agcgtttcag
     9661 ataatacatt actaatggtg ttctgcaatt ttaaaccaat ggcgtgggca tcgtcggatt
     9721 cgctaacttc ggcatccagt agaggactac tgtcatcaga ctcggtagtg gcaagttcaa
     9781 tggccaggtc cattttaaaa tcctgaaaac ctttatagcc cagggtgcga caaaagcgaa
     9841 taaccgtggc ttctccggcc tgtgtgtcgc gcgacaaatc ggcaatagat gactgtgtca
     9901 cctgtctggg gaaggctaaa atatattgcg caatacgctg ggaggcacgt gtcaggcttt
     9961 tttgcatagc acccagagtg tcaaggattt ttccgggttt aagacgtggg ggttgaggct
    10021 ccatatagtt cctgctcttg agggctgatt gcggcacaaa gcctgcaata tcgaacagag
    10081 cagagcctat caagtctgcg gcatgaaaaa aagcgcgatg taagtaaagg agggggaata
    10141 tttacatcgc gttgccaact tatgacagaa catcactgga gagtaatctg tttgctctta
    10201 cggtgtttat agcgcgccat ctgtcggatg gtttatatct ggcccggtat tgtcgccccg
    10261 cgcgttggcg tcaccgtgtg ctgtgtcggt atagcgtggt atcatgaaat cataatgtca
    10321 cctttggttc aggtttttca tccagcgtca atggcggtgc cggggcaaat aacggggcga
    10381 aaataacgcc gctgatcacc acgcttagcg agccaatgac cccataaaag aagaagttaa
    10441 ggtcagtggc atagcgtgtg cccagcacgg taatgacgct gataataatt cctaaaaccg
    10501 cactcccggc atttgctcgt ttaaagaaaa tgcccagcat gaacagaccg gtcattggcc
    10561 ctcccatcag acctatcaga ctattaaatg catcccagat ttctgattca tcggccatga
    10621 ccagccatac cgaggccgcg ctacttatca ggcccgcgac cagaataact aacttagcta
    10681 ttttcatacg gttttctggc gttccttttt tatgactcaa acgctgatag atatcggaat
    10741 taaaacaact ggaaatgctg tttaagctgc tggagatgct ggactgcgcg gcagcgaaaa
    10801 tagcggagat tatcaaccct gcaatgccga ctggcatttc ggtgaccacg aataagggca
    10861 aaatgccgcc agtgttgaat cccgccggta ataattgtgg atgttgctga tagtagacaa
    10921 ataatgccga gccgatagca aaaaagaaaa cagggatcac agcaaccagt ttggcatttg
    10981 taagtaatgt tttcttcgtt tcctctatgg agtcagtcac gatatagcgt tggaccacat
    11041 cctgactggc agtaaattgc tgaatattgg caaacagaaa accaatcatc aatacaggta
    11101 ctgtgctttc cgtccagctc cagtggaact gcgtagccgg aaagaattta tccgcctgct
    11161 gcgtcaccgt aaaaatttca ccaatgccgc cctggacttt gagacatatc actataaaaa
    11221 tcagtatcgc gctgccagaa agtaagagac cttgaataac atcagtccat attactcctt
    11281 caattccccc ccatccaggt ataaatgata cacatcacac taatcaacag taccaaaatc
    11341 accgggtcta tagcgatgaa ggggcgcaag gccagcacgg tgaggaaagt gataatggcg
    11401 atacgtccaa tatgaaacaa cataaatgac atgctggcga acagacggca gcgcacatcg
    11461 aaccgtgctt cgagatattc ataggctgat gtgactttca atttccgaaa aaacggaata
    11521 tagaaataaa aaaccagcgg taaaattgcg atagccagat actgaccaat gataaacgtc
    11581 cagtcggaag taaacgcttt ggcaggaatt gacataaatg taattgagct taacgtagta
    11641 gcaaatacac tgaccccagc cgcccaacca ggaacccggc caccaccgcg aaaataatcg
    11701 tctgctgttt tttgccgtct ggaaaaatag acaccgacta acatcatggc caggaggtag
    11761 ccaaataata caaaataatt aacgatgccg aaagaatgtg taatcatagt tctttcctgc
    11821 ttatggtttt gagtagcgtt gcggtcatcg tctgtgtatt tttatcttcc catcattcag
    11881 acgatacgat attcagatca agcaatagtt tttgttaatc tcaatgacgc taatcatgag
    11941 atgtaaaagg cagagcattt atgctccacc aatggtgatg cccagacgta tgtcctgccg
    12001 gatacctgaa atagcagcta tccgatattg cgttcaaaca ggcttcaggc ctgggtatcg
    12061 tatttgccga tagcattctt aacgtcggat tattctctga gacataaata tcaatagtaa
    12121 gcgtgttcat tttcttttcc tgttcagcgt tttactgcgt gactgaacca ctgacagata
    12181 tgctcgatac gggtgatagc ggaaccaacg gtaactgccc aggcaccatg ctcaatagca
    12241 ttggccgcca gtgcaggcgt gttatagcgc ccctcggcaa taacacgaca acctgcatga
    12301 ctcagttgtg tcaccattgc caaatctggc tcaaccggcg tgatgggacc ggtatagcca
    12361 gacagtgttg taccaatgaa ttcgattcct ttctgatggc aacttatgcc ttcattcacg
    12421 gttgaacagt ctgccatcgc cagtaatcca tgcaggcgaa tacgtgtcag taaactatca
    12481 atatcaaccg ggcgagagcg gaatgaggca tcaaaagcga taatatcggc acctgcctgc
    12541 gccagggcgt caacatcctg taaatatgga gtgatacgga ctggcgaccc tgtaaggtca
    12601 cgtttaatta tcccaataat aggaacagaa agatggggac gaacagtccg cagattctca
    12661 atgccttcaa tgcgcacagc gaccgcaccc gccgaagccg ctgcctgtgc cattgcagcc
    12721 acaatttcag gtttatccat agggctgcct ggtaccggtt ggcatgagac aatcagccca
    12781 ccgttttcgt gtacactttg ttccagcctg gctaatagtg acatccagtt ccgccttata
    12841 tattttgaag ttttactccg ttttatatta tgttgtggag tgttgctgca tcaagcaaaa
    12901 agatagaaaa atgtgaacac agtcataagg tatgtttgtc attcaattac tgcgccagcg
    12961 gatttgaggc tataacctga agctacaaga caaatacaat tcattctgac ggcagcatgc
    13021 tgtattttat taactgcttc cggcataaag ataaaatgct cagaaggagc ttatacgcca
    13081 cgggatagcc agtatgaaat gcatcacata attcttgttg tatttattca gaatgcaatc
    13141 actaatgagt ttgcccataa caggtcaccc ataatcactt ctaacatcac catagtgtgc
    13201 ttttacctcg cacatggtaa ccccatgtaa ttatttttag cgcttggtca cattttgtca
    13261 ttttcattgt tgaaattatg caccataaga tcactaatga tgaagcttta ctccagttgt
    13321 atttcttcgc atggggatgc agatgaaaaa ttttaagaaa atgatgacgc taatggcgct
    13381 atgtttatca gttgctatca ccacatcagg atatgcaacc acgcttcctg atataccaga
    13441 accactgaaa aatggtactg gcgctattga taataatggc gtgatttatg tcggcttagg
    13501 taccgcaggg acatcctggt ataaaattga tcttaaaaag caacataaag actgggagcg
    13561 tataaagtcg tttcctggtg gagctcgtga gcaatccgtg tcggtatttt taaatgataa
    13621 gctgtatgtt tttggtggcg tagggaaaaa aaacagtgaa tcaccgttgc aggtttatag
    13681 cgatgtgtac aaatactcac cggtgaaaaa tacatggcaa aaagttgata ctatatctcc
    13741 agttggatta acagggcata cgggagtaaa attaaacgaa acgatggtac ttattaccgg
    13801 aggggttaat gagcatatct ttgataagta ttttattgat atagcggctg cggatgaaag
    13861 tgaaaaaaat aaagtcatct ataattattt taataaacct gccaaagatt atttttttaa
    13921 taaaatcgta tttatctaca atgctaaaga gaacacatgg aagaatgccg gtgagctgcc
    13981 aggcgcgggg acggcaggat cgtcatcggt aatggaaaat aatttcttga tgctgattaa
    14041 tggtgagctc aaaccgggtt tacgtaccga tgtgatttac cgcgccatgt gggataacga
    14101 taagctaaca tggttgaaga acagccagtt accgccatcg cctggagaac aacagcagga
    14161 agggttggcc ggagcatttt cgggctatag ccacggtgtc ctgcttgtcg gtggtggcgc
    14221 gaattttccg ggagcaaaac aaaattatac taatggaaag ttttattccc acgaagggat
    14281 aaataaaaaa tggcgagatg aagtctatgg tttgattaat ggccattggc aatatatggg
    14341 taaaatgaaa caacctctcg gctatggtgt atcagtaagt tatggtgatg aagttttcct
    14401 tattggtggt gaaaatgcta aagggaaacc tgtttcgtct gtaacctcct ttaccat
//
LOCUS       DAJVBX010000116        14369 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.116, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000116 DAJVBX010000000
VERSION     DAJVBX010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 14369)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14369)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14369
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.116"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(196..271)
                     /locus_tag="OPV72_002883"
     tRNA            complement(196..271)
                     /locus_tag="OPV72_002883"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(236..238),aa:Ala,seq:ggc)
     gene            complement(314..389)
                     /locus_tag="OPV72_002884"
     tRNA            complement(314..389)
                     /locus_tag="OPV72_002884"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(354..356),aa:Ala,seq:ggc)
     gene            611..973
                     /locus_tag="OPV72_002885"
     CDS             611..973
                     /locus_tag="OPV72_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding transcriptional regulator"
                     /protein_id="HCR9915128.1"
                     /translation="MFKERMTPEELANLTGYSRQTINKWVRKEGWATSPKPGVQGGKA
                     RLVHVNEQVREYIRSAERSVDHHADTFTPASNASLEALLMTLAKEMTSSEQKQFTSLL
                     VREGITGLLQRLGIRDSK"
     gene            975..1367
                     /locus_tag="OPV72_002886"
     CDS             975..1367
                     /locus_tag="OPV72_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding transcriptional regulator"
                     /protein_id="HCR9915129.1"
                     /translation="MKRLRSKMTTEELAECLGVARQTVNRWIREQHWKTEKFPGVKGG
                     RARLIHIDASVREFILNIPAFRKLPAFYQAEEAFAEYANATHSHAYRQIIDAVENMSA
                     QEQEKLALFLSREGIRGFLTRLGINEAD"
     gene            complement(1421..2836)
                     /gene="gltX"
                     /locus_tag="OPV72_002887"
     CDS             complement(1421..2836)
                     /gene="gltX"
                     /locus_tag="OPV72_002887"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HCR9915130.1"
                     /translation="MKIKTRFAPSPTGYLHVGGARTALYSWLFARHHGGEFVLRIEDT
                     DLERSTPEAIEAIMDGMNWLNLEWDEGPYFQTKRFDRYNAVIDEMLEAGTAYKCYCSK
                     ERLEQLREDQMAKGEKPRYDGRCRHSHEHHADDEPCVVRFANPQDGSVIFDDQIRGPI
                     EFSNQELDDLIIRRTDGSPTYNFCVVVDDWDMEITHVIRGEDHINNTPRQINILKALN
                     APVPMYAHVSMINGDDGKKLSKRHGAVSVMQYRDDGYLPEALLNYLVRLGWSSGDQEI
                     FTREEMIKLFSLGAVSKSASAFNTDKLLWLNHHYINTLAPEYVATHLQWHIEQENIDT
                     RNGPQLAELVKLLGERCKTLKEMAQSCRYFYEDFSEFDADAAKKHLRPVARQPLEVVR
                     DKLSAITDWSAENVHHAIQATADELEVGMGKVGMPLRVAVTGAGQSPALDVTVHAIGK
                     TRSIERINKALGFIAERESQQ"
     gene            3095..3170
                     /locus_tag="OPV72_002888"
     tRNA            3095..3170
                     /locus_tag="OPV72_002888"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3128..3130,aa:Val,seq:tac)
     gene            3216..3291
                     /locus_tag="OPV72_002889"
     tRNA            3216..3291
                     /locus_tag="OPV72_002889"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3249..3251,aa:Val,seq:tac)
     gene            3333..3408
                     /locus_tag="OPV72_002890"
     tRNA            3333..3408
                     /locus_tag="OPV72_002890"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3366..3368,aa:Val,seq:tac)
     gene            3413..3488
                     /locus_tag="OPV72_002891"
     tRNA            3413..3488
                     /locus_tag="OPV72_002891"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3446..3448,aa:Lys,seq:ttt)
     gene            complement(3651..4535)
                     /locus_tag="OPV72_002892"
     CDS             complement(3651..4535)
                     /locus_tag="OPV72_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCR9915131.1"
                     /translation="MERAHRIDLKLLRYFLAVAEELHFGRAAARLNMSQPPLSIHIKE
                     LEQQLGTLLFIRHSRSVALTHAGKVLMEESRRLLANANQALARVEQIGRGEAGRIELG
                     VVGTALWGRMRPAMRHFLKANPNVEVLFREKSPGMQMALLERRELDAGIWRMAIEPAV
                     GFTSIRLHESAFMVAVPEDHDLASRDSVPLSALRNEYFVTLPSVHSDWGFLQRVCQQA
                     GFSPMIIREVVEPQTVLAMISMGIGITLMADGYAQMSWPGVVFRPLEERIPADLYIVY
                     DQQQATPALEKLVAALTV"
     gene            complement(4587..4745)
                     /locus_tag="OPV72_002893"
     CDS             complement(4587..4745)
                     /locus_tag="OPV72_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1427 family protein"
                     /protein_id="HCR9915132.1"
                     /translation="MKEIILSSGIGFGIGAFFTLCRIPIPAPNVLPGVLSIVFMYIGY
                     LVVKSIFY"
     gene            complement(4804..6060)
                     /locus_tag="OPV72_002894"
     CDS             complement(4804..6060)
                     /locus_tag="OPV72_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside permease"
                     /protein_id="HCR9915133.1"
                     /translation="MGITSRLKVMSFLQYFIWGSWLVTLGSYMINTLDFTGANVGMVY
                     SSKGLAAIIMPGIMGIIADKWLRAERAYMLCHLVCAGALLYATTVTDPQTMFWVMLVN
                     AMAYMPTIALSNSVSYSCLAKAGQDPVTSFPPVRVFGTIGFIVAMWTVSLMGLELSSA
                     QLYIASGASLLLALYALTLPKIPVAEKKANTTLVSKLGLDAFVLFKNPRMAIFFLFAM
                     MLGAVLQITNVFGNPFLHDFARNPEFADSFVVKYPSILLSVSQMAEVGFILTIPFFLK
                     RFGIKTVMLMSMLAWTLRFGFFAFGDPSPFGFVLLLLSMIVYGCAFDFFNISGSVFVE
                     QEVDSSIRASAQGLFMTMVNGVGAWIGSLLSGMAVDYFSIDGVKDWQTIWLVFAAYAL
                     ALAVIFALFFKYQHHPEKLSTKSLAH"
     gene            complement(6115..6948)
                     /gene="xapA"
                     /locus_tag="OPV72_002895"
     CDS             complement(6115..6948)
                     /gene="xapA"
                     /locus_tag="OPV72_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_448816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthosine phosphorylase"
                     /protein_id="HCR9915134.1"
                     /translation="MPHALFSHNPEYCIDIIHAHKPAFTPRVAFILGSGLGALADQIE
                     DAVAISYEKLPGFPVSTVHGHAGELVLGHLAGVPVACMKGRGHFYEGRGMAVMTDAIR
                     TLKLLGCEVLFCTNAAGSLRPEVGPGSLVALSDHINTMPGTPMVGPNDDRYGDRFFSL
                     ANAYDADYRAMLQSVAAEKGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVV
                     PEVISARHCGLKVVAVSAITNLAEGLGDVKLSHAQTLAAAELSRQNFINLICGFLRKL
                     A"
     gene            7204..7965
                     /locus_tag="OPV72_002896"
     CDS             7204..7965
                     /locus_tag="OPV72_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915135.1"
                     /translation="MKKILTLTLSSLLIIPALTHAEFKGGFADIGLHYLDWTSDTTEK
                     TSKKSHKDDFGYLELEGGANFSWGEMYGFFDWENFYNGRHAKPSSEQRYTFKNTNRIY
                     LGDTGLNLYLHAYGTYGSPHRANFHDDMFLYGLGYNFTGNGYWFKPFFAKRYTDQTYY
                     TGDNGYVLGWVAGYSFSLGSEKFSVTNWNEYEFDRDASYAAGNGGKDGINGAVALWWN
                     ATPHLTAGVQYRYADNKLGESFLQDGIIYSIKYLF"
     gene            complement(8027..8953)
                     /locus_tag="OPV72_002897"
     CDS             complement(8027..8953)
                     /locus_tag="OPV72_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCR9915136.1"
                     /translation="MNYSLRQLRIFITVAQAKSFSRAGDRIGLSQSAVSHSVKELERQ
                     TGVRLLDRTTREVVLTEAGQQLATRLERVLDELNSILRDAGRVGTQLTGTVRVAASQT
                     ISAHLIPQCIAQSNSLYPAIDFVLHDRPQQWVLESIRQGEVDFGIVIDPGAAVDLQCE
                     AILSEPFLLLCRQDHPLAHQEWVSWQDLKQASLVLQDYASGSRPLIDAALAHFAIEAD
                     IVQEIGHPATLFPMVEAGIGISVLPALALPLPQGSHLQVKRLTPVVERQLMLARRKNR
                     SLSTAAQALWDVVRTQASELTAARAKDPLYQL"
     gene            9043..10041
                     /locus_tag="OPV72_002898"
     CDS             9043..10041
                     /locus_tag="OPV72_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461360.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bile acid:sodium symporter"
                     /protein_id="HCR9915137.1"
                     /translation="MKLFRILDPFTLTLITVVLLASFFPAEGGFVPVVEGITTAAIAL
                     LFFMHGAKLSREAIIAGGSHWRLHLWVMCSTFVLFPVLGVLFAWWAPVNVDPMLYSGF
                     LYLCILPATVQSAIAFTSLAGGNVAAAVCSASASSLLGIFLSPLLVGLVMNIHGAQGS
                     LEEVGKIMLQLLLPFVLGHLSRPWIGNWVARNKKWIAKTDQTSILLVVYSAFSEAVVN
                     GIWHKVGWGSLLFIVVVSLILLAIVIAINVFVARKCGFNKADEITIVFCGSKKSLANG
                     IPMANILFPTSVLGMMVLPLMIFHQIQLMVCAGLARRYKRQTEKLQAQQESRAAKA"
     gene            complement(10038..10256)
                     /locus_tag="OPV72_002899"
     CDS             complement(10038..10256)
                     /locus_tag="OPV72_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3820 family protein"
                     /protein_id="HCR9915138.1"
                     /translation="MEKEQLLEIANTVMPFGKYQGRRLIDLPEEYLLWFARKDQFPAG
                     KLGELMQITLLIKTEGLTQLVQPLKRPL"
     gene            complement(10258..12273)
                     /gene="ligA"
                     /locus_tag="OPV72_002900"
     CDS             complement(10258..12273)
                     /gene="ligA"
                     /locus_tag="OPV72_002900"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HCR9915139.1"
                     /translation="MEPIEQQLTELRTTLRHHEYLYHVMDAPEILDAEYDRLMRELRE
                     LEAQRPDLITPDSPTQRVGAAPLTAFNQIRHEVPMLSLDNVFDEESFLAFNKRVQDRL
                     KSTENVIWCCELKLDGLAVSILYENGVLVSAATRGDGTTGEDITSNVRTIRAIPLKLH
                     GDNIPARLEVRGEVFLPQAGFEKINEDARRTGGKVFANPRNAAAGSLRQLDPRITAKR
                     PLTFFCYGVGILEGGELPDTHLGRLLQFKAWGLPVSDRVTLCDSPQAVLDFYHNVEKD
                     RPTLGFDIDGVVIKVNSLALQEQLGFVARAPRWAVAFKFPAQEQMTFVRDVEFQVGRT
                     GAITPVARLEPVQVAGVLVSNATLHNADEIERLGLRIGDKVVIRRAGDVIPQVVNVVL
                     SERPEETRPIVFPTHCPVCGSDVERVEGEAVTRCTGGLICGAQRKESLKHFVSRRAMD
                     VDGMGDKIIDQLVEREYVHTPADLFRLTAGKLTGLDRMGPKSAQNVVNALEKAKATTF
                     ARFLYALGIREVGEATAAGLAAYFGTLEALQAATIDELQKVPDVGIVVATHVFNFFAE
                     ESNRDVIGQLLAEGVHWPAPVVINAQEIDSPFAGKTVVLTGSLSQMSRDDAKARLVAL
                     GAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGITVIDEAEMIRLLGA"
     gene            complement(12345..13331)
                     /gene="zipA"
                     /locus_tag="OPV72_002901"
     CDS             complement(12345..13331)
                     /gene="zipA"
                     /locus_tag="OPV72_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZipA"
                     /protein_id="HCR9915140.1"
                     /translation="MMQDLRLILIIVGAIAIIALLVHGFWTSRKERSSMFRDRPLKRM
                     KSKRDDDSYDDDVEEDEGVGEVRVHRVNHAPGQSQEHDAPRQSPQHQYQPPYASAQPR
                     PAAPPQPQAPMQQPVQQPVQPAPQPQQVQPSAPPVQPPQQQPAPPSQAPQPVAQPAPP
                     PSAQTFQPAEPVVEAEPVVEEAPVVEKPQRKEAVIIMNVAAHHGSELNGEVLLNSIQQ
                     SGFKFGDMNIFHRHLSPDGSGPALFSLANMVNPGTFDPEMTDFTTPGVTIFMQVPSYG
                     DALQNFKLMLQSAQHIADEVGGVVLDDQRRMMTPQKLREYQDRIREVMDANA"
     gene            13563..14324
                     /gene="cysZ"
                     /locus_tag="OPV72_002902"
     CDS             13563..14324
                     /gene="cysZ"
                     /locus_tag="OPV72_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate transporter CysZ"
                     /protein_id="HCR9915141.1"
                     /translation="MVSSSTTVPRSGVYYFSQGWKLVTLPGIRRFVILPLLVNIVLMG
                     GAFWWLFTQLDAWIPSLMSHVPDWLQWLSYLLWPIAVISVLLVFGYFFSTLANWIAAP
                     FNGLLAEQLEARLTGATPPDTGILGIMKDVPRIMKREWQKLAWYLPRAIVLLVLYFIP
                     GIGQTIAPVLWFLFSAWMLAIQYCDYPFDNHKVPFKTMRAALRTQKVANMQFGALTSL
                     FTMIPVLNLFIMPVAVCGATAMWVDCWRAKHALWK"
BASE COUNT         3536 a         3962 c         3497 g         3374 t
ORIGIN      
        1 ggcattgctt taatgctcac atcattatat aaggcgcatg aataataagt atattcgcat
       61 tatgaagcaa tctaacaaaa gctcatattg accgcaaaag cagcggcaaa cgaacgcacc
      121 tgaagagcag atcagacgcc atgaattttg tgacaaaaag caaaaacccc cgcttttcag
      181 cgagggtttg aacgttggtg gagctaagcg ggatcgaacc gctgacctct tgcatgccat
      241 gcaagcgctc tcccagctga gctatagccc catagtgctt ttacgtatac gccaaattta
      301 tcgggagtaa atttggtgga gctaagcggg atcgaaccgc tgacctcttg catgccatgc
      361 aagcgctctc ccagctgagc tatagcccca ctacgtaaag cttgtcgagt tgacgggcgg
      421 catcatatga attccctcgg catgtgtcaa cggcaaaatg aacttgccga attcaatcgc
      481 tgaaaaagca ttcaaataaa ggacattgcg gcacaactcg cattcagtag ttaaacacgt
      541 cacggtttcg actaaaatgg tgctataaaa tgaaccacta attaacccca cgactattca
      601 gggaatcgtt atgttcaagg aacggatgac gccagaagaa ctcgctaatc tcaccggtta
      661 cagccgacaa accatcaata aatgggtacg gaaagaaggc tgggcaacat cgcccaaacc
      721 tggcgtccag ggcggtaaag cccgtctggt tcatgtaaac gaacaggttc gtgaatatat
      781 ccgcagcgct gaacgttcag ttgaccatca cgcagacaca ttcacgcctg ccagcaacgc
      841 atcgcttgaa gcgctgctca tgacgctcgc caaagagatg acctcatccg agcagaaaca
      901 gtttacctct ctcctcgtgc gtgaagggat taccggtttg ttacaacgct tagggatacg
      961 cgatagcaaa taatatgaaa agattacgca gtaaaatgac cactgaagag ctggctgaat
     1021 gcctcggcgt ggccagacaa accgtcaatc gctggatcag agaacaacac tggaaaaccg
     1081 aaaaatttcc cggcgtcaaa ggcggacgcg caagactcat ccatattgat gccagcgtgc
     1141 gggagtttat tctcaatatt ccggcttttc gcaaactgcc tgcgttttat caggcggaag
     1201 aggctttcgc agaatatgcg aacgcgacgc acagtcacgc ttatcgacaa attattgatg
     1261 ccgttgaaaa tatgtctgct caggaacagg aaaaactggc gctgttttta tcgcgggaag
     1321 gtattcgcgg atttctgacg cgtttaggta tcaatgaggc ggactaacaa ataataaacg
     1381 gcaggcgtct gccctgccgt ttattctgtt tcagctggcg ttactgctga ctttcacgct
     1441 cggcgataaa gcccagcgct ttgttgatac gctcaatgct gcgggtttta ccaatcgcat
     1501 gtacggtgac atccagcgca ggcgactgcc cggcaccggt cacagccaca cgcagcggca
     1561 tccctacttt acccatcccc acttccagct catccgccgt ggcctgaatc gcgtggtgga
     1621 cgttttctgc tgaccagtcc gtaatcgccg acagcttgtc gcgcaccact tccagcggct
     1681 gacgcgccac cgggcggagg tgttttttcg ccgcatcggc gtcaaactcg ctgaagtctt
     1741 catagaagta gcggcagctc tgcgccatct ctttcagagt cttgcagcgt tcgcccagca
     1801 acttcaccag ctcagcaagc tgcgggccgt tacgggtgtc gatattttcc tgctcgatat
     1861 gccactgcaa atgcgtcgcc acatattccg gcgccagcgt attgatatag tggtggttca
     1921 gccacagcag tttatcggtg ttgaacgcgc tcgcagactt gctcaccgca ccgagggaga
     1981 acagcttgat catctcttcg cgggtgaaga tttcctgatc gccgctggac cagcccagac
     2041 gcaccagata gttcagcaac gcttccggca gataaccgtc atcgcgatac tgcatcacgc
     2101 tcaccgcacc gtgacgttta gacagctttt taccgtcgtc gccgttaatc atcgacacat
     2161 gcgcgtacat cggcaccggc gcgtttaacg ctttcagaat gttaatctgg cgcggagtat
     2221 tgttgatatg gtcttcgcca cgaatcacat gggtaatttc catatcccag tcgtccacca
     2281 ccacacagaa gttgtaggtt ggggaaccgt cggtacgacg aatgatcaga tcgtccagtt
     2341 cctgattgct gaattcgatc gggccacgga tctgatcatc aaaaataacg gaaccgtcct
     2401 gcgggttggc aaagcgcacc acgcatggct catcgtcggc atgatgttcg tggctgtgac
     2461 ggcaacgccc gtcataacgc ggcttctcgc ctttcgccat ctgatcttca cgcagttgct
     2521 ccagacgctc tttagagcag tagcatttat aggctgttcc cgcctccagc atctcgtcaa
     2581 tcaccgcgtt atagcgatca aaacgtttgg tctggaaata tgggccttcg tcccattcca
     2641 ggttcagcca gttcatacca tccatgatgg cttcaatggc ttccggcgtg gaacgctcaa
     2701 gatcggtgtc ttcaatacgc agcacgaatt caccgccgtg gtgacgtgcg aaaagccagg
     2761 aataaagagc agtacgcgcg ccgccgacgt gcagataacc tgtcgggcta ggcgcgaagc
     2821 gagttttgat tttcatgaaa tggccttacg tttataaaga tgccgacaac cggcaaatcc
     2881 tggaaagatg aatagccttg tattctatca ctgtggcttg attcctcaat gttgatccgg
     2941 tcagaacgct gcgctttgct atttccgtat agaaatcatg cagtgcgggg taattcacga
     3001 tcgttttgtt taattttacg acgaacaaac aaaaacttta gaaaatgcgt tgactcattt
     3061 tcaactctcc ctataatgcg actccacaca gcgggggtga ttagctcagc tgggagagca
     3121 cctcccttac aaggaggggg tcggcggttc gatcccgtca tcacccacca actactttat
     3181 gtagtctccg ccgtgtagat aagaaattga gaagtgggtg attagctcag ctgggagagc
     3241 acctccctta caaggagggg gtcggcggtt cgatcccgtc atcacccacc actttctcgc
     3301 cagctaaatt tcttattgtg aagtaccgaa gtgggtgatt agctcagctg ggagagcacc
     3361 tcccttacaa ggagggggtc ggcggttcga tcccgtcatc acccaccact tcgggtcgtt
     3421 agctcagttg gtagagcagt tgacttttaa tcaattggtc gcaggttcga atcctgcacg
     3481 acccaccaat gtaaaaaagc gccctaaagg cgcttttttg ctatctgcga tttataagat
     3541 tcgaacctgc cgcaggttcg ggtcttgcct gatgcgctgc gcttatcagg cctacagacg
     3601 acaccgccgc gtaggccgga taagacgtta gtcgccatcc ggcacagaca tcataccgtc
     3661 aacgccgcca ccagtttctc cagtgctggc gttgcctgct gctggtcata cacaatatac
     3721 aaatccgccg gaatacgttc ctctaacgga cggaacacca cacccggcca gctcatttgc
     3781 gcatagccat cagccatcaa cgtaatcccg atccccatac tgatcatcgc caacaccgtt
     3841 tgcggctcaa ccacttcccg aataatcatt ggcgagaaac ccgcctgttg gcatacacgt
     3901 tgtaaaaatc cccaatcaga atgtacggaa ggcaacgtaa caaaatattc attgcgcaac
     3961 gccgacagcg gcacagaatc tctggatgcc agatcgtgat cttccggaac tgcaaccatg
     4021 aatgcagatt catgcaaacg tatgctggta aaaccgactg ctggttcgat agccatacgc
     4081 cagatccctg catcaagttc ccgacgctct aacaacgcca tttgcatacc tggagacttt
     4141 tcgcgaaaaa gtacttcaac attgggattt gctttcaaaa agtgacgcat cgcaggacgc
     4201 attcttcccc acagcgccgt accaaccaca cccagttcaa tgcgccccgc ttcaccgcga
     4261 ccaatctgct ccactcgcgc cagcgcctga tttgcattgg ctaacaagcg acgtgactcc
     4321 tccattaaaa ctttcccggc atgggttaat gcaacgctgc gggaatgacg aataaacagc
     4381 aatgtaccca gttgctgttc aagttctttg atatggatac tcaagggagg ttgtgacata
     4441 tttaaccggg cagcagcccg gccaaaatgc aattcttctg caacagcgag gaaataacgt
     4501 aatagcttta gatcaatacg atgggctcgt tccatcacta tcgcactcca ggaataaggg
     4561 ataacgtctg gaatttacca tattacctag taaaaaatag atttaacgac aagataccca
     4621 atatacataa atacaataga taaaaccccg ggtaaaacat ttggtgcagg aataggtata
     4681 cggcataaag taaaaaatgc gccaatacca aatccaatac cggaggagag aataatttct
     4741 ttcatactgt gtccttgttc ataaaaatgg actggcgaac atcctctcgc cagtcaaata
     4801 aaattaatgt gctaatgatt tggtcgacag tttttctgga tggtgctgat atttaaagaa
     4861 caatgcaaaa ataacggcca atgccagagc gtaggcggca aaaaccagcc agatggtttg
     4921 ccaatctttt acgccatcaa tagaaaaata atccacggcc ataccgctta aaagagaccc
     4981 aatccacgcc cccacgccgt taaccatggt cataaacagc ccctgcgcgc tggcgcgaat
     5041 acttgagtcc acctcctgct ctacaaatac tgaccctgag atgttgaaga aatcaaatgc
     5101 gcagccataa acaatcatcg acagcagcaa tagcacaaag ccaaacgggg atggatcgcc
     5161 aaaggcaaag aagccgaaac gcagcgtcca cgccagcatg ctcatcagca ttaccgtttt
     5221 aataccaaag cgtttaagga agaacggaat ggtgaggata aagcccactt ccgccatctg
     5281 cgaaactgaa agcaagatag agggatactt caccacaaaa ctatcggcaa actcaggatt
     5341 acgggcaaaa tcatgcagga acggattacc gaagacattg gtaatttgca gcaccgcccc
     5401 caacatcatc gcaaacaaaa agaagattgc catgcgtgga tttttaaaca gaacaaaagc
     5461 atccagtccg agcttactga caagcgtggt gttcgccttc ttctcggcta ccggaatttt
     5521 cggtaacgtc agcgcataca gggccagcaa taacgatgcg ccagaagcga tgtataattg
     5581 cgcactgctc agttccagcc ccatcaggct caccgtccac atcgcaacaa taaaacctat
     5641 tgtgccgaaa acgcgcacgg gcggaaatga cgttaccgga tcctgacctg ctttcgccag
     5701 acaggagtac gaaacgctat tggataatgc aatcgttggc atatacgcca tcgcattaac
     5761 caacatcacc cagaacatcg tctggggatc ggtaacggtg gtggcgtaca ataacgcccc
     5821 cgcgcaaacc agatggcaaa gcatataggc tcgctcagcg cgcagccatt tatcagcaat
     5881 gatccccata atgcccggca tgataatcgc tgccagtcct tttgagctgt agaccatacc
     5941 gacattcgcg ccggtaaaat ccagagtgtt gatcatgtaa gagcccaggg taaccagcca
     6001 gctcccccag ataaaatatt gcaagaacga catgactttt aagcgggacg taatacccat
     6061 tttttattcc ttgccgtgag ataaagcccc aatacggggc cgtagtcatt gtgtttaggc
     6121 cagcttacgt aaaaagccgc aaatcagatt gataaagttc tgccgggaaa gttcagccgc
     6181 cgccagcgtt tgcgcatggg agagttttac atcgcccagc ccttccgcca gattggtgat
     6241 cgctgagacg gcaacaactt tgaggccaca atgacgtgcg ctaatcacct cagggacaac
     6301 ggacattccg accacatcgc cgccaataat ctgcatcatg cggatttctg ccgccgtttc
     6361 gaagttcgga cccggataag aaacaaatac gccttcagtg agggggaatc ccttctctgc
     6421 cgcaacggac tgaagcatgg cgcgataatc tgcgtcataa gcattagcca gcgagaagaa
     6481 gcgatcgcca taacgatcat cgtttggccc caccatcggc gtaccgggca tcgtattaat
     6541 gtgatcgcta agcgcaacca ggctacccgg ccccacttcc ggacgcagag atcctgccgc
     6601 attggtgcag aacaacactt cacagcccag taatttcaac gtgcgaatgg catcggtcat
     6661 caccgccatt ccacgccctt cataaaaatg tccgcggcct ttcatacagg ccaccggaac
     6721 acccgccaga tggccgagca ccagttcacc agcatggccg tgtacggtgc tgacgggaaa
     6781 tcccggcaat ttctcgtaag aaatggctac cgcatcttcg atttgatccg ccagagcacc
     6841 caacccggag cctaaaataa acgcgactcg cggggtaaat gccggtttat gtgcatgaat
     6901 aatatcaata caatactcag gattatgaga aaaaagagcg tgaggcataa gtttccttgt
     6961 tctatcggat ttaatttgac tcctttttat aacgaccatc gccccttgct gaccaataca
     7021 cttttcacgt gtcatcaata gccatttaat atcgatagat ttagatcgct tctgtattaa
     7081 tacagaggga aaacagtatt ggtttttgct tgcacttcat attaacaata tgccgctttc
     7141 atatttataa attgcctctt tttaattaac ccattaataa ttatcggcat agggaaatat
     7201 gctatgaaaa aaattcttac tctgacgctt tcttctttac tcattattcc cgcactcacc
     7261 catgcggaat ttaaaggcgg gttcgccgat atcggcctcc attacctcga ctggacatca
     7321 gacaccacgg aaaaaaccag taaaaaatcc cataaagatg attttgggta cctggaactg
     7381 gaaggcggag cgaattttag ctggggagaa atgtacgggt tcttcgactg ggaaaatttt
     7441 tacaatggcc gccacgctaa accaagcagc gaacagcgtt acacctttaa aaataccaac
     7501 cgtatttatc tgggcgatac aggattaaac ctctatctcc atgcctacgg gacgtacggt
     7561 tcacctcatc gcgctaattt ccatgatgac atgtttctct atggtttagg ctataacttc
     7621 acaggtaacg gttactggtt taaacccttc tttgccaaac gttataccga tcagacctac
     7681 tacacaggcg ataatggtta tgtattaggt tgggtggccg gctatagctt ctcgttgggt
     7741 agtgagaaat tcagcgtaac gaactggaat gagtatgagt ttgaccgcga tgcgtcctac
     7801 gctgcgggca atggcgggaa agatggcatt aatggcgcag tagcgctgtg gtggaatgcg
     7861 actcctcacc tgaccgcagg agtacaatat cgttacgctg ataataagtt aggagaatcc
     7921 ttcctgcagg atggcattat ttattccatc aaatacctgt tttaacacac tgccctgtca
     7981 aaaatggcag ggcaagaccg cacctcacac acggacagat agatatttat agctgataca
     8041 gcggatcttt cgccctcgcg gcggttaatt cgctggcctg agtacgcacc acgtcccaca
     8101 acgcctgcgc cgccgtggag agcgatcggt tttttcgccg cgccagcatg agctgccttt
     8161 caactacggg cgtcagccgt ttaacctgta agtggctgcc ctgcgggagc ggtaacgcca
     8221 gcgcgggcag cacgctgatg ccgattcccg cttccaccat tggaaacagc gtggccgggt
     8281 gaccaatctc ctgcacgata tccgcctcaa tagcaaaatg ggccagcgcc gcatcaatca
     8341 gcggtcgact gccggaagca taatcctgta agaccagcga ggcctgttta agatcctgcc
     8401 agctcaccca ttcctgatgc gccagcggat gatcctggcg acacaacagt aaaaaaggct
     8461 ctgataagat ggcttcacac tgtaaatcca ccgctgcgcc gggatcgata acgatgccaa
     8521 aatccacttc accctggcgg atgctctcca gcacccactg ctgcggacga tcgtgcaata
     8581 caaaatcaat agcgggataa agtgaattac tttgggcaat gcattgcgga ataagatgcg
     8641 cagaaatggt ttggctcgcg gcaacgcgca cggtgccggt taattgtgtc cctactctgc
     8701 ctgcatcgcg cagtatgctg ttcagttcat caagcacccg ctccagacgc gtcgccagct
     8761 gttgccccgc ctcggtcagc accacctcac gcgtggtgcg atccaacagt ctgacgccgg
     8821 tttgccgctc cagctctttt acgctatgac tgaccgcaga ctggctcagt ccaatcctgt
     8881 cccctgcccg actaaaactt ttggcctggg cgacggtaat aaaaatccgc agttgacgca
     8941 gtgaatagtt catcgactag attcatatat agatgcaata aatcaatttt atttctcaaa
     9001 gcgaaaaacg caaaatagct gcaccgactt tcaggagttt ttatgaaact ttttcgtatc
     9061 cttgaccctt tcacgctgac acttatcacc gtggtactac tggcctcttt tttcccggcg
     9121 gaaggtggct ttgtgcctgt cgttgaaggc attacgacag cggctatcgc tctgctgttt
     9181 tttatgcatg gcgcgaagct ttcgcgtgaa gcgatcatcg ctggcggcag ccactggcgg
     9241 ttgcatctgt gggtcatgtg cagcactttt gtgctctttc ctgtcctcgg cgtgctgttt
     9301 gcctggtggg cgcctgtcaa tgtcgaccct atgctctaca gcggctttct gtatctgtgt
     9361 attttgcccg ccaccgtgca gtcggcgatt gcatttactt cactcgcggg cggcaacgtc
     9421 gcggccgcgg tgtgctcagc gtctgcgtcc agcctgctgg gcattttcct gtcgccgctg
     9481 ctggtcggtc tggtaatgaa tattcatggc gcgcagggca gtctggaaga ggtgggcaaa
     9541 attatgctgc aactgctgct gccttttgtg ctgggacacc tgtctcgccc gtggatcggc
     9601 aattgggtcg cgcgcaacaa aaagtggatc gcgaaaacgg atcagacctc tattctgttg
     9661 gtggtctact cggcgttcag cgaagcggtg gtcaacggca tctggcacaa agtcggctgg
     9721 ggatcgctgc tgtttatcgt cgtggtcagc ctcatactgc tggcgatcgt catagccatt
     9781 aacgtctttg tcgcccgtaa atgcggcttc aataaagccg acgaaatcac tattgtcttc
     9841 tgcggttcga aaaaaagcct ggccaacggg atcccgatgg ccaatattct gtttccgacg
     9901 tcagtgctgg gtatgatggt attaccgctg atgatcttcc accagatcca actgatggtc
     9961 tgcgcagggc tggcgcggcg ctacaaacgc cagaccgaga agttacaggc gcagcaggaa
    10021 agccgcgccg cgaaagctta aagcgggcgt ttcaggggct gcaccagttg cgtcagcccc
    10081 tcggttttaa tcagcagcgt gatttgcatc aactccccta gtttacccgc cggaaattga
    10141 tctttacggg caaaccacag caaatactct tccggaaggt cgatcaatcg acgtccctga
    10201 tatttgccaa agggcatcac ggtgttggcg atttcaagca gctgctcttt ttccatctca
    10261 ggcacccagt aagcggatca tttccgcttc atcaatcacg gtaataccca gttcctgcgc
    10321 tttggccagt ttggagcccg ccgcttcacc ggcaatcacc agatcggttt tcttcgatac
    10381 gctgcctgcc actttcgcgc ccagagccac taaacgcgct ttagcgtcat cgcgggacat
    10441 ctggctcagg ctaccggtta gtaccacggt tttaccggca aacgggctat cgatctcttg
    10501 cgcattaatg actaccggcg cgggccagtg aaccccttcc gccagtagct gcccaatcac
    10561 gtcacgattg ctctcttcgg caaaaaagtt aaagacgtgc gtagcgacca caatccccac
    10621 gtcgggtact ttctgcaact cgtcaatggt ggcagcctgc agcgcctcca gcgtgccgaa
    10681 gtacgccgcc agccccgccg ccgtcgcttc acccacttca cggatgccca gcgcatagag
    10741 aaaacgcgca aaagtcgtcg ctttggcttt ttccagcgcg ttaacaacat tttgcgcgga
    10801 ctttggcccc attcggtcca ggccggtcag tttacccgcc gtcagacgga acagatccgc
    10861 tggcgtatgg acatactccc tttccaccag ttggtcgatg atcttatcgc ccatcccgtc
    10921 tacatccatc gcccggcgcg acacaaaatg tttcagcgac tctttacgct gcgcgccgca
    10981 aatcagcccg ccggtacaac gggtaacggc ttcgccttcg acgcgctcta cgtccgatcc
    11041 gcacaccgga cagtgcgttg gaaacacaat cggacgcgtc tcttcagggc gttcggacag
    11101 aaccacgttg accacctgag ggatcacatc gcctgcccga cggataacca ccttatcgcc
    11161 aatgcgcaag ccaagccgct caatttcatc ggcattatgc aacgtggcat tgctgaccag
    11221 cacaccagcc acctgaaccg gttctagacg cgccaccggc gtaatcgccc cggtgcgccc
    11281 gacctgaaac tcaacgtcgc gcacaaaagt catctgctcc tgagcaggaa atttaaacgc
    11341 caccgcccag cgcggcgcgc gggccacaaa gcccagctgt tcctgcaaag ccagcgagtt
    11401 gaccttaatc accacgccgt cgatatcaaa accgagcgtg gggcgatctt tttcgacgtt
    11461 gtgataaaaa tccagtactg cctggggaga atcgcacagc gtcacgcgat cgctgaccgg
    11521 taacccccac gctttaaatt gcagcaaccg tcccagatgc gtatccggca actctccgcc
    11581 ttccagaata ccgacgccgt agcagaaaaa tgttagcggt cgcttcgccg taatacgcgg
    11641 atcgagctga cgcaacgagc ccgccgccgc gttacgcgga ttagcaaaca ctttgccgcc
    11701 agtacggcgc gcgtcttcat tgatcttttc gaacccggcc tgcggtaaaa atacctctcc
    11761 gcgaacttca agacgcgccg gaatgttatc gccgtgcagc tttaacggaa tggcgcgaat
    11821 cgtgcgcacg tttgaagtga tatcttcacc ggtggtgccg tcgccacgcg tcgcagcgct
    11881 caccagcacg ccgttttcat acagaatgct gaccgccagg ccatccagtt ttagctcgca
    11941 gcaccagatg acattttccg tgctttttag acgatcctgc actcgcttgt taaacgccag
    12001 gaagctttct tcatcaaata cgttatcgag cgacagcatc ggtacttcat ggcgaatctg
    12061 gttgaatgcc gtcagcggcg ccgcgccaac gcgctgcgtg ggcgaatccg gcgtgataag
    12121 gtccggacgt tgcgcctcca gctctcgcag ttcccgcatc aggcggtcat attcggcgtc
    12181 gagaatctcg ggcgcatcca tcacatgata cagatattca tgatggcgaa gcgtggttcg
    12241 cagttctgtc agttgttgtt cgattggttc catatcacac catcaatgat aaaaaacccc
    12301 cgacaggcgg gggttacgtt aaaaatgtca cacctgcgtt aacctcaggc gttagcgtcc
    12361 atcacctcgc ggatgcggtc ctgatattcg cgcagtttct gcggcgtcat catccgacgc
    12421 tggtcatcca gcacgacgcc accgacctca tcagcgatat gctgcgcgga ttgcagcatc
    12481 agcttgaaat tctgcagcgc atcgccgtaa gacggtacct gcataaagat agtgacgcca
    12541 ggcgtagtga agtccgtcat ttcaggatcg aacgttcccg gattgaccat attcgcgaga
    12601 ctgaacaagg ccgggccgct gccgtccggg ctcaaatgac gatggaaaat attcatatcg
    12661 ccaaatttaa agcctgactg ctgaatactg ttcagtaaca cttcaccatt aagctcgctg
    12721 ccatgatggg ccgcgacgtt cataatgatg accgcctctt tacgctgcgg tttttccaca
    12781 accggcgctt cttccactac cggttccgcc tcaaccacag gttccgcagg ctggaaggtt
    12841 tgcgctgatg gcggcggcgc gggctgcgca acaggctgcg gcgcttgcga cggcggtgca
    12901 ggctgctgtt gcggcggctg taccggcggc gcagatggct gaacctgctg aggctgcggc
    12961 gcaggttgga ccggttgctg aaccggctgt tgcatcggcg cttgcggctg cggcggcgcc
    13021 gctggacgcg gttgcgcaga cgcataaggc ggctggtact ggtgttgcgg cgactgacga
    13081 ggggcatcat gctcctgcga ctggccgggg gcatgattta cgcggtgaac acgaacttca
    13141 cccacgcctt cgtcttcttc gacatcgtcg tcatacgagt cgtcgtcgcg tttcgatttc
    13201 atgcgtttta gtggacgatc gcggaacata gaagatcgtt ctttacggct ggtccagaaa
    13261 ccatgtacca gtaaagcgat tatggcgatc gcgccaacaa tgattaatat cagacgcaaa
    13321 tcctgcatca ttatattctc tgttgttcta acaccttgcc accacggcaa acatttactc
    13381 actaagagta tttgccgatt acgtcaagtg caagtgtact gttggctttc gcagcataaa
    13441 gatgaaggaa aatgtgcttt ttgctgtttt ttcgaacatt tccgaactat ccaccgtctg
    13501 ataaccgggt aagatatccc acgtttaccc agggctttaa gaaaaaggag tatgtcctga
    13561 atatggtttc atcatccaca accgtaccac gtagcggcgt ctattatttc tcgcaaggat
    13621 ggaagttagt caccctaccg ggaatccgcc gctttgttat tttacctttg ctggtcaata
    13681 ttgtgctgat gggcggcgca ttttggtggc tgtttaccca gcttgacgcc tggatacctt
    13741 cgttgatgag tcatgtgccg gactggctgc aatggctgag ctatctgctg tggccgattg
    13801 cggttatctc tgttctgttg gtctttggct attttttctc taccctcgcc aactggatcg
    13861 ccgcgccgtt taacggcctt ttagccgaac agcttgaggc gcggttaacc ggcgctacgc
    13921 cgccagatac cggcatactc ggcatcatga aagatgtacc gcgcattatg aaacgtgaat
    13981 ggcaaaagct ggcgtggtat ctgccgcgcg ctattgtgct gctggttctc tattttattc
    14041 ctggcattgg ccaaaccatc gcgccggtgc tgtggttttt gttcagcgcc tggatgctgg
    14101 cgatccagta ttgcgactac ccgtttgata accacaaagt gccgtttaaa acgatgcgcg
    14161 ccgcgttgcg cacgcagaag gtggcgaata tgcaatttgg cgcgctcacc agcctcttta
    14221 cgatgattcc ggtgcttaac cttttcatta tgcctgtcgc cgtctgtggc gcgacggcaa
    14281 tgtgggttga ttgctggcgt gctaaacacg cgttatggaa ataacgtaaa aatgtataaa
    14341 taagagatgg cttagagcct atcccacca
//
LOCUS       DAJVBX010000117        14319 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.117, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000117 DAJVBX010000000
VERSION     DAJVBX010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 14319)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14319)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14319
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.117"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(197..1387)
                     /locus_tag="OPV72_002903"
     CDS             complement(197..1387)
                     /locus_tag="OPV72_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bcr/CflA family multidrug efflux MFS
                     transporter"
                     /protein_id="HCR9915142.1"
                     /translation="MTTRQHSSFAIVFILGLLAMLMPLSIDMYLPALPVISAQFGVPA
                     GSAQMTLSTYILGFALGQLIYGPMADSLGRKPVILGGTLVFAAAAVACALAQTIDQLI
                     VMRFFHGLVAAAASVVINALMRDIYPKEEFSRMMSFVMLVTTIAPLMAPIVGGWVLVW
                     LSWHYIFWILAIAAILASVMIFALIKETLPVERRQPFHIRTTIGNFAALFRHKRVLSY
                     MLASGFSFAGMFSFLSAGPFVYIEINHVPPQDFGYYFALNIVFLFVMTIINSRFVRRV
                     GALNMFRAGLWIQFAMAVWMVFSALMGIGFWALVVGVAAFVGCVSMVSSNAMAVILDE
                     FPHMAGTASSLAGTFRFGIGAIVGALLSLATFNSAWPMIWSIALCAACSILFYLYASR
                     PKKR"
     gene            complement(1415..2110)
                     /gene="rsuA"
                     /locus_tag="OPV72_002904"
     CDS             complement(1415..2110)
                     /gene="rsuA"
                     /locus_tag="OPV72_002904"
                     /EC_number="5.4.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase RsuA"
                     /protein_id="HCR9915143.1"
                     /translation="MRLDKFIAQQLGVSRAIAGREIRGNRVTVDGDIIKNAAFKLLPE
                     HAVAYDGNPLAQQHGPRYFMLNKPQGYVCSTDDPDHPTVLYFLDEPVAYKLHAAGRLD
                     IDTTGLVLMTDDGQWSHRITSPRHHCEKTYLVTLESPVADDTAAQFAKGVQLHNEKDL
                     TKPATLEVITPVQVRLTISEGRYHQVKRMFAAVGNRVVELHRERIGAITLDENLAPGE
                     YRPLTEEEIASVG"
     gene            2262..4022
                     /locus_tag="OPV72_002905"
     CDS             2262..4022
                     /locus_tag="OPV72_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HCR9915144.1"
                     /translation="MIFTLRPYQQEAVDATLSHFRRHRTPAVIVLPTGAGKSLVIAEL
                     ARVARGRVLVLAHVKELVAQNHAKYCALGLEADIFAAGLKRKESQGKVVFGSVQSVAR
                     NLDAFQEEFSLLIVDECHRIGDDEDSQYQQILTHLSKVNPHLRLLGLTATPFRLGKGW
                     IYQFHYHGMVRGNDNALFRDCIYELPLRYMIKHGYLTPPERLDMPVVQYDFSRLQAQS
                     NGLFSEADLNRELKKQQRITPHIISQIMEFAQTRKGVMIFAATVEHAKEIVGLLPADD
                     AALITGDTPGPERDALIDNFKAQRFRYLVNVSVLTTGFDAPHVDLIAILRPTESVSLY
                     QQIVGRGLRLAPGKTDCLILDYAGNPHDLYAPEVGSPKGKSDNVPVQVFCPACGFANT
                     FWGKTTADGTLIEHFGRRCQGWFEDDDGHREQCDFRFRFKNCPQCNAENDIAARRCRE
                     CDAILVDPDDMLKAALRLKDALVLRCSGMTMQHGQDEKGEWLKITYYDEDGADVSERF
                     RLHTPAQRTAFEQLFIRPHTRTPGVPLRWITAADIVAQQALLRHPDFVVARMKGQYWQ
                     VREKVFDYEGRFRRAHELRG"
     gene            4147..4431
                     /gene="rplY"
                     /locus_tag="OPV72_002906"
     CDS             4147..4431
                     /gene="rplY"
                     /locus_tag="OPV72_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000494192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25"
                     /protein_id="HCR9915145.1"
                     /translation="MFTINAEVRKEQGKGASRRLRAANKFPAIIYGGSEAPIAIELDH
                     DQVMNMQAKAEFYSEVLTLVVDGKEVKVKAQAVQRHAYKPKLTHIDFVRA"
     gene            complement(4540..5160)
                     /locus_tag="OPV72_002907"
     CDS             complement(4540..5160)
                     /locus_tag="OPV72_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915146.1"
                     /translation="MSKGIRQRPPVNFSLFRQVLYAHIVAFLMMLMLGMVFTVLSLVL
                     FYTYGANWLLSLFICPLFLLSGLFITGFAFKSTWSSIRYYYDKGQLKRYGLNLDATLT
                     HKEKVEIRIDNAKRQVRVDELELHVLFDFQFDSKTWSCGDLLTNEKVFDALNDGQTIP
                     IRILPWKPESASVRQRALFNRLKGMNTAAETTDPRLGEALIECGEV"
     gene            complement(5188..6195)
                     /gene="yejK"
                     /locus_tag="OPV72_002908"
     CDS             complement(5188..6195)
                     /gene="yejK"
                     /locus_tag="OPV72_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein YejK"
                     /protein_id="HCR9915147.1"
                     /translation="MSLDINQIALHQLIKRDEQNLELVLRDSLLEPTTTVVEMVAELH
                     RVYSAKNKAYGLFNEESELAQALRLQRQGEEDFLAFSRAATGRLRDELAKYPFADGGI
                     VLFCHYRYLAVEYLLVTVLNNLSSMRVNENLDINPTHYLDINHADIVARIDLTEWETN
                     PQSTRYLTFLKGRVGRKVADFFMDFLGASEGLNAKAQNRGLLQAVDDFTAEAQLDKAE
                     RQNVRQQVYSYCNEQLQAGEEIELESLSKELSGVSEVSFSEFTAEKGYELEESFPADR
                     STLRQLTKYAGSGGGLTINFDAMLLGERIFWDPATDTLTIKGTPPNLRDQLQRRTSGG
                     K"
     gene            6375..6602
                     /locus_tag="OPV72_002909"
     CDS             6375..6602
                     /locus_tag="OPV72_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YejL family protein"
                     /protein_id="HCR9915148.1"
                     /translation="MPQLSRYSDEHVEQLLSELLSVLEKHKAPTDLSLMVLGNMVTNL
                     INTSVAPAQRQAIANSFARALQSSISEDNAH"
     gene            6634..8394
                     /gene="pbgA"
                     /locus_tag="OPV72_002910"
     CDS             6634..8394
                     /gene="pbgA"
                     /locus_tag="OPV72_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin transport protein PbgA"
                     /protein_id="HCR9915149.1"
                     /translation="MVTHRQRYREKVSQMVSWGHWFALFNILLATLLGSRYLFVADWP
                     TTLAGRIYSYLSIVGHFSFLVFATYLLILFPLTFIVMSQRLMRFLSAILATAGMTLLL
                     IDSEVFTRFHLHLNPIVWELVINPDQNEMARDWQLMFISVPVILLIEMLFATWSWQKL
                     RSLTRRRHFARPLAAFFFVSFIASHLIYIWADANFYRPITMQRANLPLSYPMTARRFL
                     EKHGLLDAQEYQRRLVEQGNPEAVSVQYPLSNLHYRDMGTGQNVLLITVDGLNYSRFE
                     KQMPELATFAEQNIDFTRHMSSGNTTDNGIFGLFYGISPGYMDGVLSTRTPAALITAL
                     NQQGYQLGLFSSDGFASPLYRQALLSDFSMPAAQTQSDAQTASQWIDWLGRYAQEDNR
                     WFSWISFNGTNIDDSNQKNFVKRYASAASDVDAQINRVLNALREAGKFDNTVVIITAG
                     RGIPLTPEENRFDWSQGHLQVPLVIHWPGTPAQRINVLTDHTDVMTTLMQRLLHVSTP
                     ANEYSQGQDIFTVPRRHNWVTAADGSTLAITTPQMTLVLNNNGHYQTYDLHGEKIKDQ
                     KPQLSLLLQVLTEEKRFIAN"
     gene            8468..8544
                     /locus_tag="OPV72_002911"
     tRNA            8468..8544
                     /locus_tag="OPV72_002911"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:8502..8504,aa:Pro,seq:ggg)
     gene            complement(8855..9077)
                     /locus_tag="OPV72_002912"
                     /pseudo
     CDS             complement(8855..9077)
                     /locus_tag="OPV72_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000457616.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4113 domain-containing protein"
     gene            complement(9165..11531)
                     /gene="sspH2"
                     /locus_tag="OPV72_002913"
     CDS             complement(9165..11531)
                     /gene="sspH2"
                     /locus_tag="OPV72_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system effector E3
                     ubiquitin transferase SspH2"
                     /protein_id="HCR9915150.1"
                     /translation="MPFHIGSGCLPATISNRRIYRIAWSDTPPEMSSWEKMKEFFCST
                     HQTEALECIWTICHPPAGTTREDVINRFELLRTLAYAGWEESIHSGQHGENYFCILDE
                     DSQEILSVTLDDAGNYTVNCQGYSETHRLTLDTAQGEEGTGHAEGASGTFRTSFLPAT
                     TAPQTPAEYDAVWSAWRRAAPAEESRGRAAAVQKMRACLNNGNAVLNVGESGLTTLPD
                     CLPAHITTLVIPDNNLTSLPALPPELRTLEVSGNQLTSLPVLPPGLLELSIFSNPLTH
                     LPALPSGLCKLWIFGNQLTSLPVLPPGLQELSVSDNQLASLPALPSELCKLWAYNNQL
                     TSLPTLPSGLQELSVSDNQLASLPTLPSELYKLWAYNNRLTSLPALPSGLKELIVSGN
                     RLTSLPVLPSELKELMVSGNRLTSLPMLPSGLLSLSVYRNQLTRLPESLIHLSSETTV
                     NLEGNPLSERTLQALREITSAPGYSGPIIRFDMAGASAPRETRALHLAAADWLVPARE
                     GEPAPADRWHMFGQEDNADAFSLFLDRLSETENFIKDAGFKAQISSWLAQLAEDEALR
                     ANTFAMATEATSSCEDRVTFFLHQMKNVQLVHNAEKGQYDNDLAALVATGREMFRLGK
                     LEQIAREKVRTLALVDEIEVWLAYQNKLKKSLGLTSVTSEMRFFDVSGVTVTDLQDAE
                     LQVKAAEKSEFREWILQWGPLHRVLERKAPKRVNALREKQISDYEETYRMLSDTELRP
                     SGLVGNTDAERTIGARAMESAKKTFLDGLRPLVEEMLGSYLNVQWRRN"
     gene            complement(11700..11903)
                     /locus_tag="OPV72_002914"
     CDS             complement(11700..11903)
                     /locus_tag="OPV72_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCR9915151.1"
                     /translation="MPDTDENRRADIHAAGSLKTVKSFKGFIRRKSCAGRQNRKLNAR
                     ALIPDDLVIVESDPEKIDTLAVK"
     gene            complement(12200..12991)
                     /locus_tag="OPV72_002915"
     CDS             complement(12200..12991)
                     /locus_tag="OPV72_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber protein"
                     /protein_id="HCR9915152.1"
                     /translation="MISLEDASLTKKGIVKLSSATDSDSEALAATPKAVKTVMGEVRT
                     KAPLDSPAFTGTPTTPTPPGDAKGLQTTNAEFVRKLIAALVGSVLEPLDTLQELADAL
                     GNDPNFATTVLNKLAGKQPLDETLTALSGKSVDGLIEYVGLRETISRAADALQKSQNG
                     GDIPDKDLFVRRIGAARAFDGAVIIGCDDNPWTTAEFIVWLESQGAFNHPYWMCRGSW
                     SYAYNKIITDTGCGNICLAGAVIEVMGVRGAMTIRVTTSHSVSGW"
     gene            13107..13265
                     /locus_tag="OPV72_002916"
     CDS             13107..13265
                     /locus_tag="OPV72_002916"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915153.1"
                     /translation="MDAYDADDEAAAAVLAVSADAALADASPAFVVAVPALLSADAAD
                     EAADQNSP"
     gene            13294..13497
                     /locus_tag="OPV72_002917"
     CDS             13294..13497
                     /locus_tag="OPV72_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence protein MsgA"
                     /protein_id="HCR9915154.1"
                     /translation="MPTIKKLADARDVILHELILHELIGHLSCAVVTVKSMQATNVNH
                     VCTKTEKAHLHPILEKMFAVAGK"
     gene            complement(13689..14153)
                     /locus_tag="OPV72_002918"
     CDS             complement(13689..14153)
                     /locus_tag="OPV72_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001724370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyloxyacyl hydrolase"
                     /protein_id="HCR9915155.1"
                     /translation="MSFAAGESIRRGGVEHLYTAFLTYSEPSDFFFLQARNNLELGGF
                     KAKGSDDCSKHSGSVPCNKYNQGVLGISKDVALVHFAGIYTGIGLGAYIKSKSRDDMR
                     VNSAFTFGEKAFLGWNFGAFSTEAYIRHFSNGSLTDKNSGHNFVGASISYNF"
BASE COUNT         3465 a         3950 c         3466 g         3438 t
ORIGIN      
        1 aaccttttta actacaatga tgtgactttt tacataaatg gattttacat aaaataaaca
       61 taaaggagga aaatgatgaa ttggtaattg atatacatca actatgaaag ccgtttggct
      121 ttgccatcgt gtagcggata gcgcccccca acgccgcctg cgcattcttc ggcgccattg
      181 agggacaccg cgcccgtcac cgttttttgg gacggctggc gtagagataa aacagaatgg
      241 aacaggcggc gcaaagcgca atcgaccaga tcatcggcca cgcactgtta aaggtagcca
      301 gcgacagcaa cgcgccgacg atagcgccaa taccaaagcg gaaagtgccc gccaacgaag
      361 acgccgttcc ggccatatgc ggaaactcat ccaaaatgac cgccatcgca ttggacgaaa
      421 ccatcgacac acagccgaca aacgccgcaa cgccaaccac cagcgcccag aatccaatgc
      481 ccatcagcgc gctgaaaacc atccacaccg ccatcgcaaa ctgaatccat agcccggccc
      541 gaaacatgtt tagcgcccct acccgtctga caaaacggct gttgataatc gtcatcacaa
      601 acagaaatac gatgttcaac gcgaagtagt agccgaaatc ctgcggcgga acatgattaa
      661 tttcgatata gacaaacggc cccgcgctca aaaaagagaa cataccggca aaactgaacc
      721 cgctcgccag catatagctc agtacgcgtt tgtggcgaaa caacgcggca aagttaccta
      781 ttgtggtacg aatatgaaaa ggctgacgcc gctcaacggg cagcgtctct ttaatcaaag
      841 caaagatcat gactgacgcc agaatcgccg caatagccag tatccagaag atatagtgcc
      901 agcttaacca taccaacacc cagccgccaa caatgggcgc cattaacggc gctatcgtag
      961 tgaccagcat gacaaatgac atcatgcgcg aaaactcttc ctttggataa atatcccgca
     1021 tcagcgcatt gatgacgacg cttgccgccg cagccaccaa accgtgaaag aaacgcatca
     1081 cgatcagttg atcgatagtc tgcgccaacg cacaggcgac cgccgcagcg gcaaatacca
     1141 gcgtcccgcc caggatgacc ggcttacgcc cgaggctatc cgccatcggt ccatagataa
     1201 gctgacccag cgcaaacccc agaatatagg tgctgagcgt catctgcgcg ctaccggcag
     1261 gcacgccgaa ttgcgcagaa atcaccggca gcgctggaag atacatatca atcgacagcg
     1321 gcattaacat ggccaacagg ccaagaataa agacaatggc aaaggaagag tgctgccggg
     1381 tggtcacatc gaactcctga atttaacgag atagttagcc gacgctggcg atttcttctt
     1441 cagtcaacgg gcggtactcg ccgggagcca gattctcatc cagcgtaatg gcgccaatcc
     1501 gttcgcggtg cagttccaca acgcgattgc ctactgcggc aaacatccgc ttcacctgat
     1561 gataacggcc ttcgctgatg gtcagacgga cctgcacagg tgttatcacc tccagcgtag
     1621 cgggtttagt gagatctttt tcattatgca actgcacgcc tttcgcaaat tgcgctgccg
     1681 tatcgtcggc caccggcgac tccagggtca ccagataggt tttttcacag tgatggcgcg
     1741 gcgacgtaat gcggtgcgac cactgaccgt catctgtcat taacaccaga ccggtagtat
     1801 cgatatccag acgtcctgcg gcatgcagct tatacgccac cggctcatcc aggaaataca
     1861 gcaccgttgg atgatcggga tcatcggttg aacaaacgta tccctgcggc ttgttaagca
     1921 taaaatagcg tggcccgtgt tgctgcgcta agggattgcc gtcatacgca accgcatgtt
     1981 ccgggagcag tttgaaggcc gcatttttaa tgatgtcgcc atcgacggta acgcggttac
     2041 cacgaatttc acgcccggca atagcgcggc tgacgccaag ctgctgagcg ataaatttat
     2101 caagtcgcat gtgtgtgatt tagcctgtaa taatacggaa atcgggcatt ctacccgaaa
     2161 aaagggaatt gctatccgct cagtatagcg ggctaactat atccctcaag ggaaatgatt
     2221 catggcatac tattcccgga accgtttaac gtagtgagac catgattttt acactccgcc
     2281 cctaccagca agaagccgta gacgccacgc tcagccactt tcgccgccac cgtacgcccg
     2341 ccgtgattgt tctgccgacc ggcgcaggta aaagcctggt gatcgccgaa ctggcgcgcg
     2401 tcgcccgcgg acgggtactg gtgctggcgc atgtgaaaga gctggtcgcg cagaaccacg
     2461 ccaaatattg cgcgctgggg ctggaagcgg atattttcgc cgccggactc aaacgtaaag
     2521 agagtcaggg caaagtcgtg ttcggcagcg tacagtcggt ggcgcgtaat cttgacgcct
     2581 tccaggagga gttttcgctg ttgattgtcg atgaatgcca ccgcatcggt gacgatgaag
     2641 acagtcagta tcagcaaatc ctcactcacc tgagtaaagt taatcctcac ttacgtctgc
     2701 ttggactcac cgccacgcct tttcgcctcg gaaaaggctg gatttatcaa tttcattatc
     2761 acggtatggt gcgcggcaac gacaacgctc tgtttcgcga ctgtatttat gaactgccgc
     2821 tgcgctatat gattaaacac ggctatctga cgccgcctga gcggcttgat atgccagtgg
     2881 tccaatacga tttcagccgc ctgcaggccc aaagcaatgg gctgttcagc gaagccgacc
     2941 tgaaccgcga gctgaaaaag cagcagcgga ttacgccgca catcatcagc cagattatgg
     3001 aatttgcgca aacgcgcaaa ggcgtgatga ttttcgccgc cacggtcgaa catgcgaaag
     3061 agattgtcgg tctgcttccg gcggacgacg cggcgctgat taccggcgat acgccagggc
     3121 ccgagcgcga cgcgctgatt gataatttca aggcgcagcg ttttcgctat ctggttaacg
     3181 tctcggtact gaccaccggc tttgacgccc cacacgttga tctcatcgcg attctacgtc
     3241 ccacggagtc agttagtctt taccaacaaa ttgtcgggcg tggtctgcgc cttgcgccgg
     3301 gaaagaccga ttgcctgatt cttgattacg caggcaaccc gcacgacctg tatgccccgg
     3361 aggtcggtag cccgaaggga aaaagcgata acgtccctgt ccaggtattt tgcccggcct
     3421 gcggctttgc caacaccttc tgggggaaaa ccactgccga cggcacgctg attgaacact
     3481 ttggccgtcg ctgccagggc tggtttgagg atgacgacgg ccatcgcgag cagtgcgatt
     3541 ttcgctttcg cttcaaaaac tgcccgcagt gtaatgccga aaacgatatt gccgcccgac
     3601 gctgccggga atgtgacgcc attctggtcg acccggacga tatgttaaaa gcggcgctca
     3661 ggctcaagga tgcgttagtc ctgcgctgta gcggaatgac gatgcagcat gggcaggatg
     3721 agaaaggcga atggctgaaa atcacttact atgacgagga cggcgcggat gtcagtgagc
     3781 gcttccgctt gcacacgccc gcccagcgta ccgctttcga acagctattt attcgcccgc
     3841 atacgcgcac gcccggcgtt cctttacgct ggatcacggc ggcggatatt gtcgcgcagc
     3901 aggcgctgtt gcggcatccc gattttgtgg tcgcgcggat gaaaggccag tactggcagg
     3961 tgcgtgaaaa agtgttcgac tatgaaggcc gcttccgccg ggcgcacgaa ttacgtggtt
     4021 aattgtactt ttcattgatg taacggcgat ttgagtatag aatcccgccc gcctttgcat
     4081 acgcaaagca gatcacttac ctgttgctgg gtcgcctgta gcaggaatta ttaaagagag
     4141 atttaaatgt ttactatcaa cgcagaagta cgtaaagagc agggtaaggg tgcgagccgc
     4201 cgcctgcgcg ccgctaacaa gttcccggca atcatctacg gcggttctga agccccgatt
     4261 gctatcgaac tggaccacga ccaggtgatg aacatgcaag ctaaagctga attctacagc
     4321 gaagttctga ccctcgttgt tgacggtaaa gaagtaaaag ttaaagctca ggctgtacag
     4381 cgtcacgctt acaaaccgaa gctgactcac atcgacttcg ttcgcgcgta atcgcctgga
     4441 agttgaagaa aaaccccgcc ccggcggggt ttttttatgc gtttaattga atttgacgac
     4501 atgcagagca acgagaaccc actttgcttt tctgctttct tacacctcgc cacattcaat
     4561 tagcgcctcc cctaatcgag gatctgtagt ttccgccgcg gtattcatac ctttaagccg
     4621 attgaataat gcccgttgac gaacgctggc actttccggt ttccatggca aaattcgtat
     4681 tggtatcgtt tgcccatcat tcaacgcatc aaataccttt tcattggtca gtaagtcgcc
     4741 gcagctccat gtcttgctat caaactgaaa atcaaataag acatggagtt ccagttcatc
     4801 tacacgcact tgacgctttg cattatcgat gcgtatttcc accttctctt tatgcgtcaa
     4861 agttgcatca agattgagtc cataccgttt caactgcccc ttgtcgtaat agtaacgtat
     4921 gctggaccag gttgatttaa aagcaaatcc agtaatgaat aaaccactta acaagaacag
     4981 cgggcatatg aacaagctca gtaaccagtt ggcgccataa gtataaaaca gtaccaacga
     5041 gagaacggtg aacaccatgc cgagcatcaa catcatcaaa aatgcgacaa tgtgcgcata
     5101 caaaacctgc cgaaataaac tgaaattaac aggcggcctc tgacgtattc ctttactcac
     5161 tacggcgtcc ttttatgtcg tatgccttta tttcccgccc gacgtgcgtc gctgcaactg
     5221 atcgcgcaaa ttcggcggcg tccctttgat agtcagggta tcggtcgccg ggtcccagaa
     5281 aatccgctcg cccagtagca tcgcatcaaa gttaatcgtt aacccgccgc cgctgccggc
     5341 atatttggtt aactggcgta gcgtactgcg atctgccggg aagctctctt ccagctcata
     5401 gcctttttcg gcggtaaatt cgctgaagct gacttcactg acgccggaaa gctctttaga
     5461 cagcgattcc agctcaatct cttccccggc ttgtaactgc tcgttgcagt agctgtacac
     5521 ctgctgacgc acgttctgac gttctgcttt atccaactgc gcttctgcgg tgaaatcatc
     5581 cactgcctgc aacaggccgc gattctgcgc tttggcgttc aacccttcgc tggcgccgag
     5641 gaaatccata aagaagtcag cgaccttgcg ccctacccga cctttcagga acgtcaggta
     5701 gcgggtcgat tgcggattag tttcccactc ggtaagatcg atacgcgcca cgatatccgc
     5761 atggttgata tcaagataat gcgtcgggtt aatgtccaga ttttcattga cccgcatact
     5821 gctcaggttg ttcagtaccg taaccagcag atactccacc gccaggtaac gataatggca
     5881 gaacaataca atgccgccgt ccgcaaaggg atatttcgcc agttcgtcac gcaggcgtcc
     5941 ggtcgccgcc cggctaaagg caagaaaatc ttcttccccc tgacgttgca accgcagcgc
     6001 ttgcgccagt tcactctctt cattaaacag gccatacgcc ttattcttgg cgctatagac
     6061 ccgatgcagt tcagccacca tctcgacaac ggtggttgtc ggctccagca atgaatcgcg
     6121 caagaccagc tcaagatttt gctcatcgcg cttgataagc tggtgcaggg caatctggtt
     6181 gatatccaga ctcatgataa actctccttt aagaccgggc ggtattcaac caccgcctgc
     6241 cggaagacgc aagcaatcgc cctgtcattt caggcgttat ccgtaacgcg aatgatttag
     6301 gggataaaaa tgcagaaaaa aaactgttgc tacggtaata tgttgccctt tcatgaacaa
     6361 acagattttg atttatgcca caactctccc gctatagtga tgaacatgtt gaacaactgc
     6421 tgagcgaact gctcagtgta ctggaaaaac ataaggcgcc gaccgatctt tccctgatgg
     6481 tactgggaaa tatggtcacc aaccttatca acaccagcgt ggcgccggct caacgccagg
     6541 cgattgcgaa ctcttttgcc cgcgccttgc agtcttcgat tagcgaagac aacgcgcact
     6601 aaaaagccga ctccggagaa acaagcgaca ggtatggtaa ctcatcgtca gcgctaccgt
     6661 gaaaaagtct cccagatggt tagctggggg cactggttcg ctctgttcaa tatactgttg
     6721 gctacgttgc tcggcagccg ttacctgttt gtcgccgact ggccgacaac gcttgcgggt
     6781 cgcatatact cctacctgag cattgtcggg cactttagct ttctggtgtt cgccacctat
     6841 ttgcttattc tttttccgct cacgtttatc gtgatgtccc agcggctgat gcggttttta
     6901 tcagccattc tggcgaccgc gggtatgacg ttgttgctta tcgacagcga agtctttacc
     6961 cgttttcacc tgcatcttaa ccccattgtc tgggaactgg tcatcaaccc tgaccagaac
     7021 gaaatggcgc gcgactggca gcttatgttt attagcgtgc cagttatctt attgattgag
     7081 atgctatttg cgacatggag ttggcaaaag ctgcgcagtc tcacgcgccg ccgccatttc
     7141 gcaaggccgc ttgcggcatt ctttttcgtc tcctttatcg catcgcatct tatctacatc
     7201 tgggcagacg ctaattttta ccggccgatt accatgcagc gggcaaacct gccgctctct
     7261 tatccgatga cggcgcgacg ttttcttgaa aaacacggtc tgctggatgc gcaggaatat
     7321 cagcgccgtc tggtagagca aggcaatccg gaagcggtct ccgttcagta cccgctcagc
     7381 aatttgcact atcgcgatat gggcaccggt cagaatgtgc tgctcattac cgtagacggc
     7441 ctgaactatt ctcgctttga gaagcagatg ccggagctgg ctacatttgc cgagcaaaac
     7501 atcgacttca cccgtcatat gagttcaggg aataccactg ataacggtat tttcggcctg
     7561 ttctatggca tatcgccagg ctatatggat ggcgtgttat ccaccagaac gcctgcggcg
     7621 ctcattaccg cgttgaatca gcaaggctac caactgggac tgttttcttc ggatggcttc
     7681 gccagcccgc tttatcgtca ggcattactg tccgatttct cgatgccggc agcgcaaacg
     7741 cagtctgatg cgcaaacggc cagccagtgg atagactggc ttgggcgcta cgcacaggaa
     7801 gataaccgct ggttctcatg gatatcgttt aacggtacta acattgatga cagtaaccag
     7861 aaaaattttg ttaagcgtta cgccagtgcc gccagcgacg tggatgcgca aatcaatcgg
     7921 gttctgaacg cgctgcgaga ggccggtaaa ttcgacaata ctgtcgtgat cattaccgca
     7981 ggacgcggca taccgttgac gccggaagaa aatcgcttcg actggtcgca aggtcatctg
     8041 caagtaccgc tggtgatcca ctggccgggg acgcctgcgc agcgtattaa tgtgcttacc
     8101 gatcataccg atgtgatgac cacgttgatg caacgcctgt tacatgtcag cacgccagcg
     8161 aacgaatatt cacagggcca ggacatcttt accgttccac gtcgtcataa ctgggtaacg
     8221 gcggcagacg gcagtacgct ggcaatcacg acgccgcaaa tgaccctggt gctcaataat
     8281 aacggtcatt atcagaccta tgacttacac ggcgagaaga tcaaagatca gaagccgcag
     8341 ctcagtctgc tgctgcaagt gctaacagaa gagaaacgtt ttatcgctaa ctgattaatt
     8401 ataaatcagt tagcaccgtt tccccttgca ttcgcgttgg aaagaggtag tattagcacc
     8461 cacaagtcgg cacgtagcgc agcctggtag cgcaccgtca tggggtgtcg ggggtcggag
     8521 gttcaaatcc tctcgtgccg accaaaattc cccttaaaag ccagcctgcc agggctggtt
     8581 tttttatata tccaatttgc aaatggtgaa atgatggtga aatagctatc gaaggtcact
     8641 gcaaattgac ttcaagctcc ctccaacgcg aaaagttgaa cagatgactt aaatacattg
     8701 attagtcatc cttaaccagt agaatccgcc acgactggta actattcaat acacgcacta
     8761 tcgaacgatc gccagtttgc cgcagcccgt tcttgcatac aatgtggctg cggcacacca
     8821 tcacatcaga aatttgaaaa tcagggtaaa cctgtcactt aacctgaagc aggtcttcat
     8881 agcgggtggt atatcgggat gacagtatgt ttctcttcat agcccactgt tgctggatac
     8941 cctccccggc aaagtacagc tttcccctgc ccttctttgc attcaggtga tccagtactt
     9001 ccatcggctt ctcgctaccg gcgcgcggcg cgttatcatc gaaaaagttg cgccgcgccc
     9061 tgactgaaga agtctcccct atttcacctg tacatcatcc gtactgtctg atgttgttcg
     9121 tccgggaata tctttgtcgc accgcacctc attcacctgg tgcatcagtt acgacgccac
     9181 tgaacgttca gatagctccc cagcatctcc tccacaagag gtcgcaggcc atccaaaaat
     9241 gtctttttcg cgctctccat cgctcttgct ccgatagtgc gctctgcatc ggtattaccg
     9301 accagcccag acggtctcag ctctgtgtca gacagcatcc ggtacgtttc ctcataatcc
     9361 gatatttgct tttcacgaag cgcgttaacg cgtttcggcg ctttgcgctc cagcactctg
     9421 tgtaacggcc cccactgcag tatccactcc ctgaactcgc ttttttcagc ggctttcacc
     9481 tgaagctccg cgtcctgaag gtctgtaacc gtcacgccgg atacgtcaaa gaaacgcatt
     9541 tctgacgtca cgctggtcag cccgagtgat ttcttcagct tattctgata cgccagccag
     9601 acctcaattt catcaacgag agccagcgtt ctgacctttt cccgggcaat ctgttccagt
     9661 tttcccagac ggaacatctc acgccccgtg gcaaccagcg ccgcgagatc gttatcgtat
     9721 tgcccttttt ctgcattatg taccagctgt acgttcttca tctggtgcaa aaaaaatgtg
     9781 acccggtcct cgcagcttga ggttgcctct gttgccatag caaaggtgtt tgctctcaac
     9841 gcctcatctt cagccagttg tgccagccag gacgatatct gtgccttaaa ccccgcgtcc
     9901 tttatgaagt tttccgtctc actcagtctg tccaggaaga ggctgaaggc gtcggcgtta
     9961 tcttcctgtc cgaacatatg ccatctgtct gcaggagccg gttccccctc ccgggcaggc
    10021 accagccagt cagcggccgc caggtgcagt gcccgagttt cccggggggc ggaggctccc
    10081 gccatatcga atcgtattat ggggcctgaa tagccaggcg cgctggtgat ctcccgcagc
    10141 gcctgcaaag tacgttcaga cagtgggttc ccttccagat ttacggttgt ctctgaagac
    10201 agatgaatga gactttccgg caggcgggtc agctggttac gatagaccga cagcgacagt
    10261 agtcctgacg gcagcatcgg caggctggtc agccggttac cagataccat cagctccttc
    10321 agttctgacg gcagcaccgg cagactggtc agccggttac cagatacaat cagctccttc
    10381 agtcctgacg gcaacgccgg caggctggtc agccgattat tataggccca cagcttatat
    10441 aattctgacg gcagcgtcgg caagctggcc agttggttat cagataccga cagctcctgt
    10501 agccctgacg gcaacgtcgg caggctggtc agctggttat tataggccca cagcttacat
    10561 aattctgacg gcagcgccgg caggctggcc agttggttat cagataccga cagctcctgt
    10621 agccctggcg gcaacaccgg caggctggtc agttgattac caaagatcca cagcttacat
    10681 agtcctgacg gcagcgccgg caggtgggtc agcgggttac taaagatcga cagttccagt
    10741 agtcctggcg gcagcaccgg caggctagtc agctggttac cagagacctc cagcgtccgc
    10801 agttctggcg gcagcgccgg caggctggtc agattattat caggaataac cagtgtggta
    10861 atatgcgcgg gtaaacagtc tggcaaggtg gtaagacctg attctcccac gttaagcact
    10921 gcattgccat tattcaggca ggcacgcatt ttctgtaccg ctgctgcacg gccgcgtgac
    10981 tcttctgcgg gtgcagccct tctccacgct gaccagacag catcatactc tgctggcgtc
    11041 tgtggagccg ttgtggcagg gaggaaggat gtcctgaatg tcccggatgc cccttccgcg
    11101 tgtcctgtgc cctcctcacc ctgtgctgtg tccagggtga ggcgatgtgt ttcactgtac
    11161 ccctggcaat ttacggtata gttcccggca tcatcaaggg tgactgacaa tatctcctga
    11221 ctgtcttcat ccagaataca gaagtaattt tccccgtgct ggccggaatg aatgctttcc
    11281 tcccatccgg catacgcgag cgtcctgagc agttcaaatc tgttgatcac atcctcccgc
    11341 gtcgttccgg ccggcgggtg acaaatcgtc cagatgcact ccagcgcttc agtctggtgc
    11401 gttgagcaaa aaaattcctt cattttttcc caggaactca tttcaggggg ggtatcagac
    11461 caggcaatac gataaatgcg gcgattactg atggtggcgg gaagacatcc gcttccaata
    11521 tgaaagggca taacaaaaaa cctttataaa tttacatata gtatctgtcc ggcagacatc
    11581 atctcttcct ggtcttaatt tcacaataag gttatcggcg gattcatggt cgtcctgaca
    11641 tggcgggctt cagaaggtgc agaagaaaaa tccgttatga tgaccggatg gcgggactgt
    11701 cattttacag ctaaagtgtc gattttttca gggtcgcttt ccacgatgac cagatcatcc
    11761 ggtatcaacg cccgggcgtt caattttcga ttctgcctgc ctgcgcagct cttccggcga
    11821 ataaaccctt tgaacgactt taccgtcttt aaactgccag cagcatgaat atcagcgcga
    11881 cggttttcat ccgtatcagg caactctgca acgctctggc cagcaggcca cagcccggaa
    11941 acatcacgcg taatacacgt aataacatcg ttatcgtcgt aggtaatttt cagcgtgtct
    12001 gctgaaaata attgctggca cccataccag tcctgaccat cctctgattt aagatacgcc
    12061 gcatcggcga ataatgtgtc atctggttcc ggtgcatacg gaatgaaatt tttaatattt
    12121 aaaaactgtt tgttcttttt attttttttc cgctgtcata attattcctt cttatacact
    12181 tggggctgtc acccacgtat caccaaccag atactgaatg ggacgttgtc acccgaatag
    12241 tcatcgcgcc acgcactccc attacctcaa tcactgcgcc agcgagacag atattaccgc
    12301 agccagtatc cgtgatgatt ttgttataag cgtaagacca ggagccacga cacatccagt
    12361 aagggtgatt gaatgcgccc tgagactcca gccagacgat aaactccgcc gtcgtccacg
    12421 gattatcatc acagccgata ataactgcgc catcaaacgc tcgcgcggca ccgatacgac
    12481 gcacaaacaa atccttgtcc ggaatatcgc cgccattctg tgatttttgt aatgcatcgg
    12541 cggcacgact tatggtttct cgcaaaccaa cgtattcgat aagaccgtca acgctttttc
    12601 ctgacagcgc cgtcagggtt tcgtccagcg gctgcttgcc cgccagttta ttcagtaccg
    12661 tggtggcaaa gttcggatca tttcccaacg cgtcagccag ttcctgcagg gtgtccagtg
    12721 gctccagtac ggaaccaacc agcgcggcaa tcagtttgcg gacaaactcc gcgtttgttg
    12781 tctgaagccc tttagcatcg cctggcggcg tcggtgtggt cggcgttcca gtgaatgccg
    12841 ggctgtccag cggcgctttg gtccgtacct cacccataac ggtttttacc gcctttggtg
    12901 tggccgccag cgcttcgctg tcactgtccg tggcactgct taatttaacg ataccttttt
    12961 tcgtcaggct tgcatcttcc agggaaatca cgtctgcgat atcctcggcc cgtttcgcgg
    13021 cctcttcggc tctggttgcc gattctccgg ctgcagctct gctttgcgct gccagtgatg
    13081 cgctggtatc agatgcggcg gcgtgggtgg atgcctacga tgctgatgac gaggcggctg
    13141 ccgccgttct ggctgtgtca gccgacgccg cgctggctga tgcctccccg gcttttgtgg
    13201 tcgccgtacc tgcgctgctc tccgcagatg ctgcggatga agctgccgac caaaattccc
    13261 cttgaaaacc agcctgtcag ggctggtttt tttatgccta caattaaaaa gttagctgat
    13321 gccagagacg ttattttgca tgaactgatt ttgcatgaac tgattggaca tctttcctgt
    13381 gcagtggtca cagtaaagtc aatgcaggca actaacgtaa accatgtttg tactaaaaca
    13441 gaaaaagcgc atctacaccc tatactggaa aaaatgtttg cagtggcagg taaatgagta
    13501 agcaatctgt cgcagcaata ataaaacgtt ctggtaaggt aaacggccta ccacgccttt
    13561 gtcgctaaca attagcctcc ctgtcgccat agggtcgata acgatcggct attcacaaca
    13621 cgttttgtag acaacgtacg gtgattaatt actccttcag ccagcaactc gctaattgtt
    13681 attcaacttc agaaattata actaattgaa gcacctacaa aattatgccc tgaattttta
    13741 tccgtaagtg atccattcga gaaatgccgg atataagctt ctgtagaaaa agccccaaag
    13801 ttccagccaa gaaacgcttt ttctccaaag gtaaatgcag aattgacacg catatcatct
    13861 cgcgacttag attttatata agcccccaga ccaataccgg tatagatacc agcgaaatga
    13921 accagcgcca catccttcga gatacccaat acgccctggt tatatttatt acagggaacg
    13981 ctgccagaat gtttactgca atcatcgcta cccttagcct taaatcctcc taactccaga
    14041 ttatttcttg cctgtaaaaa gaaaaaatcg ctgggttcac tgtatgtcag aaaagccgta
    14101 tataagtgct caacccctcc tcttcttata ctttctcccg cagcaaaaga gatctgatgc
    14161 ttgttgccct tgccaaaaaa acattatcat tagcagaaca tgcgaatgca caaggtaata
    14221 atagatatat aaatattctc ttcatataca ctccaccacc atttcaatgt caatagttat
    14281 ttttaaccgg ctaacatatt taaaattttc tacgccacg
//
LOCUS       DAJVBX010000118        14312 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.118, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000118 DAJVBX010000000
VERSION     DAJVBX010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 14312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14312
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.118"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..714)
                     /gene="rfaP"
                     /locus_tag="OPV72_002919"
     CDS             complement(<1..714)
                     /gene="rfaP"
                     /locus_tag="OPV72_002919"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide core heptose(I) kinase RfaP"
                     /protein_id="HCR9915156.1"
                     /translation="MVELKAPLTTLWRGKDAFEEVKTLQGEVFRELEMRRTLRFELDG
                     KSYFLKWHKGTSLKEIVKNLISLRMPVLGADREWHAIHRLHELGVDTMHGVGFGEKGV
                     NPLTRTSFIITEDLTPTISLEDYCVDWAVNPPDAQVKWMIIKRVATMVRKMHAGGINH
                     RDCYICHFLLHLPFTGREEDLKISVIDLHRAQIRQHVPLRWRDKDLIGLYFSSMNIGL
                     TQRDIFRFMREYFSLPLREI"
     gene            complement(707..1831)
                     /locus_tag="OPV72_002920"
     CDS             complement(707..1831)
                     /locus_tag="OPV72_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HCR9915157.1"
                     /translation="MRVAFCLYKYFPFGGLQRDFMHIAQTVAARGHQVRVYTQSWEGE
                     CPDNFELIRVPVKSRTNHGRNAEYYAWVQHHLRDHPVDRVVGFNKMPGLDVYYAADVC
                     YAEKVAQEKGFFYRLTSRYRHYAAFERATFEHGKQTQLLMLTNKQIADFQKHYQTEAE
                     RFHILPPGIYPDRKYSQQIPNSRQIYRQKNGISEQQKLLLQVGSDFTRKGVDRSIEAL
                     ASLPESLRQNTVLCVVGQDKPKKFAALAERSGVGTNVHFFSGRNDIAELMAAADLLLH
                     PAYQEAAGIVLLEAITAGLPVLTTAVCGYAHYIVDANCGEAMTEPFRQDALNEVLLRA
                     LTQPSLRSAWAENARYYADTQDLYSLPEKAADIITGDLDG"
     gene            complement(1828..2898)
                     /gene="rfaQ"
                     /locus_tag="OPV72_002921"
     CDS             complement(1828..2898)
                     /gene="rfaQ"
                     /locus_tag="OPV72_002921"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001521713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide core heptosyltransferase
                     RfaQ"
                     /protein_id="HCR9915158.1"
                     /translation="MEKPFRRILIIKMRFHGDMLLTTPVISTLKQNYPDAKIDVLLYQ
                     NTIPILSENPEINALYGISNKGAGTKEKIKNALSLIKKLRANSYDLVVNLTDQWSVAL
                     IVRFLNAKIKISQDFGNRQSALWKKSFTHLVPYAGEHAVERTLSALKPLALKQYVTET
                     TMSYRPEHWENMRQQLKQLGVTRQYVVIQPTARQLFKCWDNDKFSQVIDAVQRRGYQV
                     VLTSGPAADEMACVDAIACGCETKPVTGLAGKTRFPELGALIDHADLFIGVDSAPGHI
                     AAAVKTPVICLFGATDHVFWRPWTDDIIQFWAGNYQPMPERHELDRNKKYLSVIPAED
                     VIAATEKMLPHEARPIDLDSLL"
     gene            3307..4584
                     /gene="waaA"
                     /locus_tag="OPV72_002922"
     CDS             3307..4584
                     /gene="waaA"
                     /locus_tag="OPV72_002922"
                     /EC_number="2.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid IV(A) 3-deoxy-D-manno-octulosonic acid
                     transferase"
                     /protein_id="HCR9915159.1"
                     /translation="MLELLYTALLYLIQPLIWIRLWVRGRKAPAYRKRWGERYGFYRR
                     PLKPGGIMLHSVSVGETLAAIPLVRALRHRYPDLPITVTTMTPTGSERVQSAFGNDVQ
                     HVYLPYDLPDALNRFLNKIDPKLVLIMETELWPNLIAALHKRHIPLVIANARLSARSA
                     AGYAKLGKFVRTLLRRITLIAAQNEEDGERFVALGAKNNQVTVTGSLKFDISVTPQLA
                     AKAVTLRSQWAPHRPVWIATSTHDGEESIVIAAHQALLHQFPNLLLILVPRHPERFPD
                     AINLVRQAGLSYITRSSGEVPSASTQVVVGDTMGELMLLYGIADLAFVGGSLVERGGH
                     NPLEAAAHAIPVLMGPHTFNFKDICARLEQASGLITITDAATLAKEVSSLLTDADYRN
                     FYGRHAVEVLYQNQGALQRLLQLLEPYLPPKTH"
     gene            4593..5072
                     /gene="coaD"
                     /locus_tag="OPV72_002923"
     CDS             4593..5072
                     /gene="coaD"
                     /locus_tag="OPV72_002923"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HCR9915160.1"
                     /translation="MQKRAIYPGTFDPITNGHLDIVTRATQMFDHVILAIAASPGKKP
                     MFTLNERVALAQKATAHLGNVEVVGFSDLMANFARDRQANILIRGLRAVADFEYEMQL
                     AHMNRHLMPQLESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPDNVHQALMDKLK"
     gene            complement(5100..5909)
                     /gene="mutM"
                     /locus_tag="OPV72_002924"
     CDS             complement(5100..5909)
                     /gene="mutM"
                     /locus_tag="OPV72_002924"
                     /EC_number="3.2.2.23"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA-formamidopyrimidine
                     glycosylase/DNA-(apurinic or apyrimidinic site) lyase"
                     /protein_id="HCR9915161.1"
                     /translation="MPELPEVETSRRGIEPHLVGATILHAHIRNGRLRWPVSDEIYRL
                     SDTPVLSVQRRAKYLLLELPDGWIIIHLGMSGSLRILSEALPAEKHDHVDLVMSNGKI
                     LRYTDPRRFGAWLWTKELEGHNVLAHLGPEPLSDEFNGEYLQQKCAKKKTAIKPWLMD
                     NKLVVGVGNIYASESLFAAGIHPDRLASSLSTEECDLLARVIKAVLLRSIEQGGTTLK
                     DFLQSDGKPGYFAQELQVYGRKGEPCRVCGTPIVATKHAQRATFYCRHCQK"
     gene            complement(6007..6174)
                     /gene="rpmG"
                     /locus_tag="OPV72_002925"
     CDS             complement(6007..6174)
                     /gene="rpmG"
                     /locus_tag="OPV72_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010847629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HCR9915162.1"
                     /translation="MAKGIREKIKLVSSAGTGHFYTTTKNKRTKPEKLELKKFDPVVR
                     QHVIYKEAKIK"
     gene            complement(6195..6431)
                     /gene="rpmB"
                     /locus_tag="OPV72_002926"
     CDS             complement(6195..6431)
                     /gene="rpmB"
                     /locus_tag="OPV72_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008457442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HCR9915163.1"
                     /translation="MSRVCQVTGKRPVTGNNRSHALNATKRRFLPNLHSHRFWVESEK
                     RFVTLRVSAKGMRIIDKKGIETVLSELRARGEKY"
     gene            complement(6649..7314)
                     /gene="radC"
                     /locus_tag="OPV72_002927"
     CDS             complement(6649..7314)
                     /gene="radC"
                     /locus_tag="OPV72_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HCR9915164.1"
                     /translation="MDTLDELLPREKMLRSGIASLSDVELLALFLRTGTPGKDVMTLA
                     KEILQHFGSLYGLLSADFAQFRGVNGIGLAKFAQLKGIAELARRYYSVRMNEESALLS
                     PEMTREFLQSQLTGEEREIFLVIFLDAQHRVLQHSRLFSGTLNHVEVHPREIVREAIK
                     LNASAVILAHNHPSGCAEPSKADKLITERVIKCCQFMDIRVLDHLIIGRGEYVSFAER
                     GWI"
     gene            7490..8710
                     /gene="coaBC"
                     /locus_tag="OPV72_002928"
     CDS             7490..8710
                     /gene="coaBC"
                     /locus_tag="OPV72_002928"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418096.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HCR9915165.1"
                     /translation="MSLAGKKIVLGVSGGIAAYKTPELVRRLRERGADVRVAMTEAAK
                     AFITPLSLQAVSGYPVSDSLLDPAAEAAMGHIELGKWADLVILAPATADLIARVASGM
                     ANDLVSTICLATPAPVAVLPAMNQQMYRAAATQHNLEVLASRGLFIWGPDSGSQACGD
                     VGPGRMLDPLAIVDKAAAHFAAVNDLRHLNIMITAGPTREPLDPVRYISNYSSGKMGF
                     AIAAAAARRGANVTLVSGPVSLPMPPFVKRVDVITALDMEAAVQAAVQQQHIFISCAA
                     VADYRAETIASEKIKKQAAQSDELIIKMVKNPDIVAGVAALSDNRPYVVGFAAETNNV
                     EEYARQKRTRKNLDLICANDVSLSNQGFNSDKNALHLFWQDGDKVLPLERKELLGQLL
                     LDEIVTRYDEKNRR"
     gene            8688..9146
                     /gene="dut"
                     /locus_tag="OPV72_002929"
     CDS             8688..9146
                     /gene="dut"
                     /locus_tag="OPV72_002929"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HCR9915166.1"
                     /translation="MMKKIDVKILDPRVGQQFPLPTYATSGSAGLDLRACLDDAVELA
                     PGATTLVPTGLAIHIADPSLAAVMLPRSGLGHKHGIVLGNLVGLIDSDYQGQLMVSIW
                     NRGQDSFTIEPGERIAQMVFVPVVQAEFNLVEAFDATERGEGGFGHSGRK"
     gene            9254..9850
                     /gene="slmA"
                     /locus_tag="OPV72_002930"
     CDS             9254..9850
                     /gene="slmA"
                     /locus_tag="OPV72_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid occlusion factor SlmA"
                     /protein_id="HCR9915167.1"
                     /translation="MAEKQTAKRNRREEILQSLALMLESSDGSQRITTAKLAASVGVS
                     EAALYRHFPSKTRMFDSLIEFIEDSLITRINLILKDEKDTSTRLRLIVLLILGFGERN
                     PGLTRILTGHALMFEQDRLQGRINQLFERIEAQLRQVLREKRMREGEGYTTDKNLLAS
                     QLLAFCEGMLSRFVRSEFKYRPTDDFDARWPLIAAQLQ"
     gene            complement(9928..10569)
                     /gene="pyrE"
                     /locus_tag="OPV72_002931"
     CDS             complement(9928..10569)
                     /gene="pyrE"
                     /locus_tag="OPV72_002931"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HCR9915168.1"
                     /translation="MKPYQRQFIEFALNKQVLKFGEFTLKSGRKSPYFFNAGLFNTGR
                     DLALLGRFYAEALVDSGIEFDLLFGPAYKGIPIATTTAVALAEHHDKDLPYCFNRKEA
                     KDHGEGGSLVGSALQGRVMLVDDVITAGTAIRESMEIIQAHRATLAGVLISLDRQERG
                     RGEISAIQEVERDYGCKVISIITLKDLIAYLEEKPDMAEHLAAVRAYREEFGV"
     gene            complement(10648..11364)
                     /gene="rph"
                     /locus_tag="OPV72_002932"
     CDS             complement(10648..11364)
                     /gene="rph"
                     /locus_tag="OPV72_002932"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006803115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HCR9915169.1"
                     /translation="MRPAGRSANQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTASIE
                     EGVPRFLKGQGQGWITAEYGMLPRATHTRNAREAAKGKQGGRTMEIQRLIARALRAAV
                     DLKTLGEFTITLDCDVIQADGGTRTASITGACVALADALNKLVANGKLKTNPMKGMVA
                     AVSVGIVNGEAICDLEYVEDSAAETDMNVVMTEDGRIIEVQGTAEGEPFSHEELLTLL
                     ALARGGIESIVATQKAALEN"
     gene            11490..12353
                     /locus_tag="OPV72_002933"
     CDS             11490..12353
                     /locus_tag="OPV72_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HCR9915170.1"
                     /translation="MIRSMTAYARREIKGEWGSATWEMRSVNQRYLETYFRLPEQFRS
                     LEPVVRERIRTRLTRGKVECMLRFEPDASAQGELILNEKLAKQLVSAANWVKMQSDEG
                     EINPVDILRWPGVMAAQEQDLDAIAAEILAALDGTLDDFIVARETEGQALKALIEQRL
                     EGVSAEVAKVRAHMPEILQWQRERLVAKLEDAQVQLENNRLEQELVMMAQRIDVAEEL
                     DRLEAHVKETYNILKKKEAVGRRLDFMMQEFNRESNTLASKSINADVTNSAIELKVLI
                     EQMREQIQNIE"
     gene            complement(12403..13305)
                     /locus_tag="OPV72_002934"
     CDS             complement(12403..13305)
                     /locus_tag="OPV72_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCR9915171.1"
                     /translation="MNLLQMDMNLLKVLYVLLETSSTGKTAQKLALSPSAVSHALMRL
                     RDALNDPLFRREGNRQIATPYAQALRDKLAPVFVSLNEELFGDKENGSRCFRVVLPPA
                     LNALLTPVLAEKGHLHQAVIECLPFARRPWRDELLDSSVDLVLAIGDHQKQVSALHYE
                     RVGTTRLIAVYGAPLRSRLENAAALNFADLQHYQHIYCLPWTKENNELDRQQARAGFE
                     RPLAFVCHDYSQLAPAVQSAPLMAIVPRPWYENLSDKRGLFVLPLAGEQAEGAIFMQY
                     RASTVEWKRRLIDAIRRKLKTYYR"
     gene            13379..14263
                     /locus_tag="OPV72_002935"
     CDS             13379..14263
                     /locus_tag="OPV72_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HARLDQ motif MBL-fold protein"
                     /protein_id="HCR9915172.1"
                     /translation="MNRYVLFFVCIFSTSALPAMAALDPSQPLSPAPPLSLFKAWAKP
                     MKPFQITEGVWYVGTENLSSILLTTPAGHILIDAGLDESAPQIKANIEAAGFRFTDVR
                     YLLSSHARLDQAGGMARLKAWSGAQLVASQPNADQMARGGRQDFALGDALPFPLVTTD
                     KIIHNQESISLGGVTVTALFTPGHLPGSTSWRVTLRNGKTLIYADSLATPDYLLINNK
                     NYPDLVTDIQSSFKTLAAQHVDIFIANKGDRFGLLEKRQQLRNGDTQAFFDSNGLQQY
                     VERSRQRFITQLTAQQPQ"
BASE COUNT         3480 a         3856 c         3539 g         3437 t
ORIGIN      
        1 aatctctcgc agggggagtg agaaatactc acgcataaac cggaatatat ctcgctgagt
       61 caggccaata ttcattgaag aaaaataaag cccaattaaa tctttgtcac gccagcgaag
      121 gggaacgtgc tgacgtatct gcgcgcgatg caggtcgatt acggagattt ttaaatcctc
      181 ttcgcgacca gtgaaaggta aatgcagaag aaagtggcaa atataacagt cgcgatggtt
      241 aattcccccg gcgtgcattt tacgtaccat agtcgcaaca cgcttaataa tcatccactt
      301 cacctgcgcg tccggtggat taacagccca gtcaacacag tagtcttcaa ggctaatggt
      361 aggcgttaaa tcttcggtga taataaatga tgttctggtt agcgggttta cgcctttttc
      421 accaaaacca acgccgtgca tcgtatcaac gcccagctca tgtagacgat gaatggcgtg
      481 ccattctctg tcagcgccca gaacaggcat acgtaacgaa atcaggttct tcacaatttc
      541 tttcagcgaa gtgcctttat gccacttcag gaagtagctt ttgccgtcca gctcaaaccg
      601 caatgttcga cgcatctcca gttctctgaa cacttcgccc tgtaacgttt tcacttcctc
      661 aaaagcatct ttaccgcgcc atagtgtggt taacggcgct ttcagctcaa ccatctaaat
      721 cacctgtgat aatatctgcg gccttctccg gtaagctgta taaatcctgg gtatcagcat
      781 aataccgcgc attttcagcc caggcgctgc gtaaggaagg ctgtgtcagc gctctgagta
      841 aaacctcatt tagcgcatcc tggcggaaag gttccgtcat cgcttcgcca cagtttgcat
      901 ccacaatata atgtgcataa ccgcacaccg cggttgtcaa caccggcaaa ccagcagtaa
      961 tggcttccag caaaacaata ccagcagctt cctgataggc tggatgcagt aaaaggtcgg
     1021 ctgccgccat taactccgca atatcattac gtccggagaa aaaatgcaca ttcgtgccga
     1081 cgccgcttct ttcagccagt gctgcaaact tcttcggctt atcctgcccg acaacacaga
     1141 gcaccgtatt ttgccgtaaa gattcgggta gcgatgccag cgcttcaata gagcgatcca
     1201 cacctttacg ggtaaagtca gaccctactt gcaacagtaa tttttgctgt tctgagatac
     1261 catttttctg acgataaatt tgacgactgt tcgggatctg ttggctatat tttctatccg
     1321 ggtaaatccc cggaggaaga atatgaaaac gctccgcttc agtctgataa tgtttttgga
     1381 agtcagcaat ctgcttattc gtcagcatta atagttgcgt ctgcttgccg tgttcaaacg
     1441 tggcgcgttc aaaagcagca taatgccgat agcgtgatgt caggcgatag aaaaatcctt
     1501 tttcctgtgc gactttttcg gcgtaacaca cgtctgcggc gtaatacaca tcaaggcctg
     1561 gcatcttatt gaacccaacc acccgatcga caggatggtc gcgcaaatgg tgttgcaccc
     1621 aggcataata ttctgcgtta cgaccgtggt tcgtccggga tttaaccggc acgcggatta
     1681 attcaaagtt atccgggcat tccccttccc atgactgagt ataaacacga acctgatgac
     1741 ctcgcgccgc cacggtttga gcaatatgca taaaatcacg ctgcagaccg ccaaaaggaa
     1801 aatatttata taagcaaaag gcaactctca tagcaggctg tccaaatcta tggggcgtgc
     1861 ctcatgcggc agcatttttt ccgtcgcggc gataacatct tcagccggaa tcacggaaag
     1921 gtatttttta ttacgatcaa gctcatgccg ttcaggcatc ggctgataat ttcctgccca
     1981 aaactgaatg atgtcgtcgg tccagggacg ccagaataca tgatccgtcg cgccaaaaag
     2041 acaaatgacc ggcgttttga ctgctgcggc aatatgaccg ggggccgaat caacgccgat
     2101 aaagagatcc gcatggtcaa tcaatgcgcc caattcagga aagcgagttt tacccgccag
     2161 accagtaacc ggttttgtct cacagccgca tgcaatagca tccacgcagg ccatctcgtc
     2221 tgcggccggg cctgacgtca gtacaacttg ataaccgcgg cgctgcacgg catcaataac
     2281 ctgcgagaat ttatcattat cccagcactt aaatagctgc cgtgccgtag gctgaataac
     2341 aacatattgt cgggtcacac caagttgttt gagctgttgt cgcatgtttt cccaatgttc
     2401 cgggcgatag ctcatggtgg tttccgtgac atactgtttt agcgctaacg gctttagcgc
     2461 ggataatgtg cgctcaacag catgttctcc cgcataaggt actaaatgtg taaagctttt
     2521 tttccataaa gcagactgac gattaccgaa atcttgcgag atttttattt ttgcgtttaa
     2581 aaaacgcaca ataagcgcca cgctccactg atcggtgaga ttgacgacca gatcatacga
     2641 gttagcacgc aattttttga ttaacgatag cgcgtttttg atcttctctt ttgttcctgc
     2701 gcctttgtta ctgatgccgt agagtgcatt aatctccgga ttttccgaca atatcggtat
     2761 ggtgttctgg taaagaagca catcgatttt tgcatcggga taattctgct tcagcgtgct
     2821 gatgacagga gtggtaagta acatgtctcc atgaaaacgc atttttataa tcagaattct
     2881 tcgaaatggc ttttccacaa gcgactcttt ggttgaaatt gtccggataa ataagcagaa
     2941 aaaagcacgc taccgcccca ggcttcacag caacccgatg gctaataccg cactcatttt
     3001 agatgcgcta gtgtaacact tctttcgcag caatccgata cgaataattt ttatacacaa
     3061 tcattttttt aattataaat tcaaagagat aataatttat ccccctcttg tgaatggtca
     3121 ttcccattgt ctggggcgac aagggcggca aatttcaatg gattgcgtaa aaatgcaaaa
     3181 ataatggggt tcagcgcctg gaatcctccc ttctgagcca atttggcgca aaaatgggaa
     3241 aagtaatggt aaagcccagg ctaaatacat agaatcccca gcacatccat aagtcagcta
     3301 tttactatgc tcgaattgct ttacaccgct cttctctacc ttattcagcc tctgatctgg
     3361 atacggcttt gggtgcgtgg acgtaaagcg ccggcctatc gtaagcgctg gggtgaacgc
     3421 tacggattct accgccgtcc gttgaaaccg ggcggaatca tgctgcattc cgtctcggtg
     3481 ggcgaaactc tggcggccat cccattggtc cgcgctctac gtcatcgcta tcccgatctg
     3541 cctattaccg taacgaccat gacgccgacc ggctcggagc gcgtccagtc cgcctttggc
     3601 aacgatgttc agcacgttta cttaccttat gatttgcccg atgcgctcaa tcgtttcctc
     3661 aataagattg atcctaagct ggtattgatc atggagactg agctctggcc aaatctgatt
     3721 gctgcgctgc acaaacgtca tattccgctg gttatcgcta atgcgcggct ttccgcccgc
     3781 tccgccgcgg gttatgcgaa gcttggcaag tttgtccgta cgctcctgcg ccgtatcacc
     3841 ctgattgccg cgcaaaacga agaagatggc gaacgctttg tggcattggg cgcgaagaac
     3901 aatcaggtca cggtcaccgg cagtctgaaa tttgatattt cagttacacc gcaactggcg
     3961 gctaaagccg ttacgctacg tagccagtgg gcgccgcacc gtccggtctg gattgccacc
     4021 agcacccacg atggcgaaga gagtatcgtt atcgccgctc accaggcgtt attacatcaa
     4081 ttcccgaatt tattactgat tctggtgccc cgccatccgg agcgtttccc ggatgctatc
     4141 aatcttgtgc gtcaggcagg gttaagctac atcactcgct cttcgggcga agtgccgtcc
     4201 gccagcaccc aggtcgtggt aggcgatacc atgggcgaat taatgttgct ctatggcatt
     4261 gccgatctcg cctttgttgg tggttcgctg gttgaacgcg gcggtcacaa cccgctggaa
     4321 gccgccgctc atgcgattcc ggtactgatg ggtccgcata cctttaactt taaagatatt
     4381 tgcgcccgtc tggagcaggc gagcgggctt atcacgatta ccgatgcggc tacgctggca
     4441 aaagaagttt cctctttact gaccgacgct gattatcgta atttctacgg acgtcacgca
     4501 gttgaagtgc tgtatcaaaa tcagggcgcg ctccagcgtc tgctgcaact gctggaacct
     4561 tatctgccac cgaaaacgca ttgagggctg tcatgcaaaa acgggcgatt tatccaggca
     4621 cgtttgatcc gattactaac ggtcatctcg atattgtgac gcgcgcaacg cagatgttcg
     4681 accatgtcat tctggccatc gccgccagcc ccggcaagaa acccatgttc accctgaacg
     4741 aacgtgtggc gctggcgcaa aaagcgaccg cacacctggg taacgtagag gtggtgggtt
     4801 ttagcgacct gatggccaat ttcgcccgcg acagacaggc gaatatcctg attcgtggtc
     4861 tgcgcgcggt ggcggatttt gaatatgaaa tgcagttggc gcatatgaat cgccatctga
     4921 tgccgcaact ggaaagcgtt ttcctgatgc cgtccaaaga gtggtcgttt atttcatcgt
     4981 cgctggtcaa agaagtggcg cgccatcagg gcgatgtgac ccactttctg cccgacaatg
     5041 tgcatcaggc gctaatggat aagttgaaat aagtttcctt ccttgccggg cctggcattt
     5101 tacttctgac agtgacggca atagaacgtc gcgcgctgtg cgtgtttcgt tgcgactatc
     5161 ggcgtaccgc atacccgaca cggctcgcct ttgcgcccgt acacctgcaa ctcctgggca
     5221 aaatagcccg gcttcccatc gctttgcaga aaatccttca gcgttgtccc gccttgttca
     5281 atagagcgca gcaaaacggc tttaatcacc cgcgccagca ggtcgcactc ctctgtcgag
     5341 agtgacgacg ccaggcggtc agggtgaata ccagcggcaa acagcgactc gctggcgtag
     5401 atattcccca cgccgaccac cagcttgtta tccatcagcc agggtttaat cgccgtcttc
     5461 ttcttcgcgc atttctgttg caaatattcg ccattaaact catcgcttag cggctccggt
     5521 cccagatgcg ccagtacgtt atgtccttcc agctctttgg tccataacca ggcgccaaag
     5581 cggcgaggat cggtataacg tagaattttg ccattgctca tcaccaaatc gacatggtcg
     5641 tgcttttccg ccggcagcgc ttccgacagt atccgcaagc ttcccgacat ccccaggtga
     5701 ataattatcc agccgtcagg caactccagc agtagatatt tagcacgacg ctgaacgcta
     5761 aggacgggtg tgtcgctcag acgataaatt tcgtctgaaa ccggccagcg cagacgaccg
     5821 ttacggatat gggcgtgcag gatagtagcg ccaactaaat gaggttcaat accccggcgg
     5881 ctggtttcaa cttcgggtaa ttcaggcata acgtctccgg ctgtgtggca ggtctcatta
     5941 atatggggac ggccagaaaa caaaaaaccc cgccgaagcg aggtttttgt tacatcaaag
     6001 cgagaattat ttgattttcg cttctttgta gatcacgtgc tgacggacaa ctggatcgaa
     6061 ttttttcagt tccagttttt ccggcttagt acgtttgttc ttcgtagtgg tatagaagtg
     6121 accagtacca gcagaagaaa ccagcttgat tttctcacga atacctttag ccatgattta
     6181 tttcctctta gtacttagta cttttcgcca cgggcacgca gttcagacag aactgtttcg
     6241 atgccttttt tatcgatgat acgcatacct ttagcagata cacgcagggt gacaaaacgc
     6301 ttctcgctct caacccagaa acggtgagag tgcaggttag gcaggaaacg gcgtttagtc
     6361 gcgttcagtg cgtgggaacg gttgttaccg gtcaccggac gcttgccagt aacttggcag
     6421 actcgggaca tgtctattct ccaaaaatca aattagctcg agcttcgtat ggggtatcgg
     6481 cgcctcgtca ggctttacag cctggtcatc gcgcagttct attgaactct cgattgccag
     6541 gcccaaatgc caaacccgag attctcaaag gtggcgtagt atacgctgac ccggcgatat
     6601 gctcaagtcc cgaacagaca aagatcccga tggatcgcgc aaagaatctt aaatccagcc
     6661 gcgttcggca aaagaaacgt actctccgcg cccaattatc aggtgatcga gcacccggat
     6721 atccataaac tggcaacact ttatcacgcg ctcagtgata agtttatctg ctttacttgg
     6781 ctctgcgcag cctgaagggt gattatgcgc cagaatgacc gctgaagcat tgagtttaat
     6841 cgcttcccga acaatctcac gcggatgcac ctctacgtgg ttaagcgtgc cggaaaacag
     6901 gcggctgtgc tgaagcaccc ggtgctgggc atctaggaag atcaccagaa agatctcacg
     6961 ctcttcgccc gtcagttggc tttgcagaaa ttcccgcgtc atttccggac tcagcaacgc
     7021 actttcctca ttcatgcgca cgctgtaata gcgccttgcc agctcagcaa tgcctttcaa
     7081 ctgcgcgaat ttcgccaggc cgatgccgtt tacgccgcga aactgcgcaa agtccgccga
     7141 cagcaggcca tacagcgacc caaagtgctg caatatctct tttgccaacg tcataacatc
     7201 ttttcccggc gtgccggtac gtaaaaaaag cgccagcagt tccacgtcgc tgagggaagc
     7261 aatgccggat ctgagcattt tttcacgcgg caataattcg tccaacgtat ccatacgcgc
     7321 acctcctttt ttaaggaagc ggcatagtgg cacagccttt gggagagatc gacgccccga
     7381 ttttgttctt gcgtagcgcc tcgcaaagtg gagcgcaggc aaagacacga cgccgtagag
     7441 attgtgataa aatagccgcc tttcaaagtc acccaacagg aaagacatga tgagcctggc
     7501 cggtaaaaaa attgttctcg gcgttagcgg cggtatcgct gcgtataaaa cgccggagct
     7561 ggtgcgccgt ttacgtgagc gcggcgctga cgtgcgcgtg gcaatgaccg aggcggcaaa
     7621 agcctttatt acccccctga gcttacaggc cgtgtcgggc tatcccgtat ccgacagtct
     7681 gcttgaccct gccgccgaag ctgcgatggg gcatatcgag ttggggaaat gggccgacct
     7741 ggtgattctt gcccccgcga ccgccgatct gatcgcccgt gtagcatcgg gtatggctaa
     7801 tgatttagtc tccaccatct gcctggcgac gccagccccg gtggccgttc ttccggccat
     7861 gaaccaacag atgtaccgcg ctgccgccac gcaacataat ctggaggtgc tcgcctctcg
     7921 cggcctgttc atttgggggc cggatagcgg cagtcaggcg tgcggcgatg taggcccagg
     7981 ccgaatgctg gacccattag ctatcgttga taaggccgcc gcgcatttcg ctgccgtcaa
     8041 cgatctgcga catcttaata tcatgattac ggcaggcccg acgcgcgaac cgctcgaccc
     8101 ggtgcgttat atttccaact acagctccgg taaaatgggc ttcgctattg cggcggccgc
     8161 agcgcgtcgc ggcgcaaatg tcacgctggt ctccggtccc gtttcgttac cgatgccgcc
     8221 ttttgtaaaa cgggttgatg tcataaccgc gctggacatg gaagccgctg ttcaggccgc
     8281 cgttcaacag cagcatattt tcattagctg cgccgccgtg gctgactatc gcgcagagac
     8341 tattgccagt gaaaaaatca aaaaacaggc ggcgcaaagt gatgaattaa taataaaaat
     8401 ggtcaaaaac ccggacattg tcgccggggt ggccgcactc agtgacaatc gcccctacgt
     8461 tgttgggttt gccgcggaaa cgaataatgt ggaagaatac gcccggcaaa aacgtacccg
     8521 taagaacctt gacctgattt gtgcaaatga tgtttctctt tcaaatcagg gatttaatag
     8581 cgataaaaac gctttacacc ttttctggca ggatggagat aaagtcttac cgcttgagcg
     8641 aaaagaactc ctgggccaat tattactcga cgagatcgtg acccgttatg atgaaaaaaa
     8701 tcgacgttaa gattctggac ccgcgtgttg gtcagcagtt tccgctgccg acttatgcta
     8761 cttctggttc tgccgggctt gacctgcgcg cctgtctcga cgacgccgta gaactggcgc
     8821 ctggcgcaac gacgttggtg cctaccggac tggccattca tatcgccgat ccatcattgg
     8881 cggcagtcat gttgccgcgt tctggcctgg gccataaaca tggtatcgtg ctgggcaacc
     8941 tggtcgggct gattgattcc gattatcagg ggcaactgat ggtttcgatc tggaaccgtg
     9001 gtcaggacag ttttaccatt gaaccgggcg aacgtatcgc gcaaatggtg tttgttccgg
     9061 tcgttcaggc cgaatttaat ctggtggaag catttgacgc taccgaacgt ggcgagggcg
     9121 gcttcggtca ttctggccgt aagtaaattt tacgcatccc cataacgtca taatactgcc
     9181 gcaagcgctg agtttgcggt tatagcgtgg gtgctcgcct ggcaagtgct tattttcagg
     9241 ggtattttgt aacatggcag aaaaacaaac tgcgaaaagg aatcgtcgcg aagaaatact
     9301 tcagtcactg gcgctgatgc ttgaatccag cgatggaagc caacgcatca cgacggcaaa
     9361 actggcggcc tcggtcggcg tttccgaagc ggcgctatac cgccattttc ccagcaagac
     9421 ccgcatgttc gatagcctga ttgagtttat cgaagatagt ctgattaccc gtatcaatct
     9481 gattttaaaa gatgaaaaag acaccagcac gcgtttgcgc ctgattgtgt tactgattct
     9541 gggttttggc gaacgcaacc ctggcctgac gcgcattctt accgggcatg cgctgatgtt
     9601 tgaacaggat cgcctgcagg ggcgcattaa tcagcttttt gaacgcatcg aagcgcagct
     9661 ccgccaggtg ctacgagaaa aaagaatgcg tgaaggcgaa ggctacacga cggataaaaa
     9721 tctgctggca agccagctgt tagccttctg tgaaggtatg ctttcacggt tcgtgcgtag
     9781 cgaatttaaa taccgcccaa cggacgattt cgacgcccgc tggccgctca ttgccgcgca
     9841 gttgcagtaa cgctgactgg atagtggctc acgccttatc caggcgacag aaatataggc
     9901 ccggtaaagc gccaccgggc aattcgctta cacgccaaat tcttcccggt atgctcgcac
     9961 agccgccaga tgctcagcca tatcaggttt ttcttccaga taggcaatca ggtctttcag
    10021 cgtaatgatg gagataacct tacaaccata gtcgcgctcc acttcctgaa tcgcggaaat
    10081 ctcgccgcgg ccacgttcct gacgatccag cgaaatcagt acgccagcca gtgtagccct
    10141 gtgcgcctga ataatctcca tcgactcgcg aatcgccgta cctgcggtaa tcacgtcatc
    10201 caccagcatc acgcggccct gtagcgcgct gcccaccaga ctcccgcctt cgccatgatc
    10261 ttttgcctct ttgcggttaa agcagtacgg caggtcttta tcgtgatgtt ccgccagcgc
    10321 aaccgccgtc gtcgtcgcga tcggaatacc tttgtacgcg gggccaaaca gcagatcaaa
    10381 ttcaataccg gaatccacca gcgcttcggc ataaaaacgg cctaacaacg ccaggtcgcg
    10441 cccggtatta aacagcccgg cgttgaagaa ataggggctt ttgcgcccgg atttcagcgt
    10501 aaactcgcca aactttagta cctgcttgtt aagcgcaaac tcaataaact ggcgctgata
    10561 cggtttcatg gattcgctcc ttttcttact ttcatcattt acgaaattta cggacaaaaa
    10621 aaaggcgact tttcagtcgc cttaaaatca attttctaac gccgccttct gcgtcgccac
    10681 aatggattca attccccctc gggccagcgc caacaaagtg agaagttctt catggctgaa
    10741 cggctcgcct tccgcggtac cctgaacttc aataatgcgg ccgtcttcag tcatcacgac
    10801 gttcatgtcg gtttctgcgg cggaatcttc aacatattcc agatcgcaga tcgcttcgcc
    10861 gttaacgatg cctacggaaa ccgccgccac catgcctttc atcggattgg ttttcagctt
    10921 accgttggca accaatttat tcagcgcatc cgccaacgcc acgcaggcac cggtaataga
    10981 cgctgtacgc gtaccgccat ctgcctggat tacatcgcag tccagcgtaa tggtaaattc
    11041 gccgagcgtt ttcagatcga ccgccgcacg cagcgcacgc gcgatcaaac gctgaatttc
    11101 catagtacga ccgccctgct taccctttgc cgcttcgcgc gcattacggg tatgggtagc
    11161 gcgaggtaac atgccatact ctgcggtgat ccacccctgg ccttgtcctt tcagaaaacg
    11221 tggaacgcct tcttcaatgg aggcagtgca caacactttg gtatctccaa attcgaccag
    11281 taccgagcct tcagcgtgtt ttgtatagtt acgggtcagg gttacgggac gcacctgatt
    11341 agcgctacgg cctgctggac gcatattgag atctccggct taaaacgaat gtggctgcgc
    11401 attatacgga cttccgatgg ttattcctat cctgacaagg catggatagc tataatcccc
    11461 tcatctctcc tttaaaaacg ggaacatcta tgatccgcag tatgaccgcc tacgcccggc
    11521 gtgaaatcaa gggtgaatgg ggtagcgcga cctgggaaat gcgctcggta aaccagcgtt
    11581 atctggaaac ttactttcgt ctgccggaac agttccgtag tcttgaaccc gtcgtgcgcg
    11641 aacgcattcg tacacgcctg acgcgcggca aagtcgaatg tatgctgcgt tttgaacccg
    11701 atgccagcgc gcaaggcgag cttattctga atgaaaagct cgcgaaacaa ttagttagcg
    11761 ccgcaaactg ggtcaaaatg cagagcgacg aaggggaaat caatccggtt gatattttgc
    11821 gctggccagg tgtcatggcg gcgcaagagc aggatctgga cgcgattgcc gcagaaattt
    11881 tagccgcact ggacggtacg ctggatgact ttatcgtcgc gcgcgaaacg gaaggccagg
    11941 cgctgaaagc gctgattgaa caacgtctgg aaggcgtcag cgccgaagta gcgaaagtcc
    12001 gcgcgcatat gccggaaatc ctgcaatggc agcgtgaacg cctggtcgcg aagctggaag
    12061 atgctcaggt tcagttggaa aacaaccgtc tggagcaaga gctggtgatg atggcgcagc
    12121 gcattgatgt ggcggaagag ctggatcgtc tcgaagcgca cgtcaaagag acttacaaca
    12181 ttctgaagaa aaaagaggcg gtaggtcgcc gtctggactt catgatgcaa gaatttaacc
    12241 gtgagtcgaa caccctggcc tctaaatcca tcaacgctga tgtaactaac tccgctattg
    12301 aattaaaagt gttgatcgag caaatgcgcg agcagatcca gaatattgaa taattctggc
    12361 gctcaatatg tcacagagtc cgccttatgc gggctctcgc gtttatcggt agtacgtttt
    12421 taatttccgg cgaatagcgt cgataaggcg tcgcttccac tctaccgtcg aagcccgata
    12481 ctgcataaaa atagcgcctt ccgcctgctc cccggcaagc ggcaggacaa aaagaccgcg
    12541 cttatcggat aaattttcat accaggggcg cggtacaatc gccattagcg gcgccgactg
    12601 gacagcaggc gcaagttgac tgtaatcatg acaaacaaac gccaacggac gttcaaaccc
    12661 ggcacgagcc tgctgcctgt ccagttcgtt gttctctttt gtccacggca aacagtaaat
    12721 gtgttgataa tgctgcagat cagcaaaatt caacgctgcg gcattctcca gacgtgaacg
    12781 caatggcgcg ccataaaccg cgatcaaacg cgtcgtcccc acccgctcgt aatgcagagc
    12841 gctgacctgc ttttgatggt cgccaattgc cagcaccaaa tcaaccgagc tatccaacag
    12901 ttcatcacgc cagggtcggc gggcaaaagg aaggcactcg atcaccgcct gatgaagatg
    12961 acctttctct gcgagaacgg gcgtaagcag cgcgttcaat gcgggaggaa gtaccacccg
    13021 gaaacaacgg gagccgttct ctttatcgcc aaacagctcc tcattaagcg aaacaaacac
    13081 aggcgccaac ttgtcacgca gcgcctgcgc ataaggcgta gcaatctggc ggttcccctc
    13141 ccgtcgaaac aacggatcgt ttagcgcatc gcgcaatctc attagcgcat gactcaccgc
    13201 agaaggcgac aaagccagct tttgcgccgt tttccccgta gagctcgtct ccagcagcac
    13261 atacagtact tttaacaggt tcatatccat ttgcagcaag ttcattaaac gtctctctta
    13321 ttgaacctga ctaaattact gccaggtata ctgcgggcgc ttcaatcagg agaacattat
    13381 gaatcgctat gtattattct ttgtatgtat attttcaaca tcagcacttc ctgccatggc
    13441 ggcattagat ccttcacaac cgttatcacc cgcgcctccg ttatcactgt ttaaagcgtg
    13501 ggctaagcct atgaagccgt ttcaaatcac agaaggcgtg tggtatgtcg gtacggaaaa
    13561 tctctcttct attctgctga ccactccggc agggcatatt cttattgatg cggggctgga
    13621 tgaaagcgca ccgcaaatta aagcgaatat tgaagcggca ggatttcgct tcactgacgt
    13681 gcgctatctg ttgagcagcc atgcgcggct ggatcaagcg gggggcatgg cacgtttgaa
    13741 agcgtggagc ggcgcacaat tggtcgccag tcaacccaac gccgatcaga tggcgagggg
    13801 tggacgacag gattttgcgc ttggcgatgc gctccccttc ccgctcgtca ccactgataa
    13861 aattatccac aaccaggaaa gcatcagcct cggaggggta accgtgacag cactattcac
    13921 gcctggacat ctgcccggct caacctcctg gcgcgtaacg ctccgcaacg gcaagacgct
    13981 aatttacgca gatagtctcg ccacacctga ctatctgctg attaacaaca aaaattaccc
    14041 tgacctggtt actgatattc agagcagctt taaaacactg gccgcccagc atgttgatat
    14101 ctttattgcc aacaaaggtg accgcttcgg gctactggag aaacgacagc aacttcgcaa
    14161 cggcgataca caggcattct ttgattccaa tggcttgcaa cagtatgtgg aacgctcgcg
    14221 tcagcgcttc atcacacaac ttaccgcaca gcagccacaa tgaaatgact caccggcggc
    14281 gcgtccaggg cgccgttcag gtaatttatc ta
//
LOCUS       DAJVBX010000119        14124 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.119, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000119 DAJVBX010000000
VERSION     DAJVBX010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 14124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14124
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.119"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(186..495)
                     /locus_tag="OPV72_002936"
                     /pseudo
     CDS             complement(186..495)
                     /locus_tag="OPV72_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463453.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(762..1478)
                     /gene="arcA"
                     /locus_tag="OPV72_002937"
     CDS             complement(762..1478)
                     /gene="arcA"
                     /locus_tag="OPV72_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003621071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator ArcA"
                     /protein_id="HCR9915173.1"
                     /translation="MQTPHILIVEDELVTRNTLKSIFEAEGYDVFEATDGAEMHQILS
                     EYDINLVIMDINLPGKNGLLLARELREQANVALMFLTGRDNEVDKILGLEIGADDYIT
                     KPFNPRELTIRARNLLSRTMNLGTVSEERRSVESYKFNGWELDINSRSLIGPDGEQYK
                     LPRSEFRAMLHFCENPGKIQSRAELLKKMTGRELKPHDRTVDVTIRRIRKHFESTPDT
                     PEIIATIHGEGYRFCGDLQD"
     gene            1574..1714
                     /locus_tag="OPV72_002938"
     CDS             1574..1714
                     /locus_tag="OPV72_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915174.1"
                     /translation="MTKVRNCVLDALSINVNNIISLVVGTFPLDPTVSKTAVILTILT
                     AT"
     gene            2114..2800
                     /locus_tag="OPV72_002939"
     CDS             2114..2800
                     /locus_tag="OPV72_002939"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA/rRNA methyltransferase"
                     /protein_id="HCR9915175.1"
                     /translation="MRVTIVLVAPARAENIGAAARAMKTMGFTDLRIVDSQAHLEPAT
                     RWVAHGSGDIIDNIEVFHTLADALHDVDFTVATTARSRAKFHYYASPAELVPLLQEKS
                     RWMRHAALVFGREDSGLTNDELALADVLTGVPMAADYPSLNLGQAVMVYCYQLAGLMQ
                     QTPESVDIADESQLQALRARLLRLLTTLEAADDHKLTDWLQQRIGLLGQRDTAMLHRL
                     VHDIEKKLTK"
     gene            3014..3079
                     /gene="thrL"
                     /locus_tag="OPV72_002940"
     CDS             3014..3079
                     /gene="thrL"
                     /locus_tag="OPV72_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thr operon leader peptide"
                     /protein_id="HCR9915176.1"
                     /translation="MNRISTTTITTITITTGNGAG"
     misc_feature    3015..3135
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00506"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Thr leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF00506"
     gene            3161..5623
                     /gene="thrA"
                     /locus_tag="OPV72_002941"
     CDS             3161..5623
                     /gene="thrA"
                     /locus_tag="OPV72_002941"
                     /EC_number="1.1.1.3"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aspartate kinase/homoserine
                     dehydrogenase I"
                     /protein_id="HCR9915177.1"
                     /translation="MRVLKFGGTSVANAERFLRVADILESNSRQGQVATVLSAPAKIT
                     NHLVAMIEKTIGGQDALPNISDAERIFSDLLAGLASAQPGFPLARLKMVVEQEFAQIK
                     HVLHGISLLGQCPDSINAALICRGEKMSIAIMAGLLEARGHRVTVIDPVEKLLAVGHY
                     LESTVDIAESTRRIAASQIPADHMILMAGFTAGNEKGELVVLGRNGSDYSAAVLAACL
                     RADCCEIWTDVDGVYTCDPRQVPDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQF
                     QIPCLIKNTGNPQAPGTLIGASSDDDNLPVKGISNLNNMAMFSVSGPGMKGMIGMAAR
                     VFAAMSRAGISVVLITQSSSEYSISFCVPQSDCARARRAMQDEFYLELKEGLLEPLAV
                     TERLAIISVVGDGMRTLRGISAKFFAALARANINIVAIAQGSSERSISVVVNNDDATT
                     GVRVTHQMLFNTDQVIEVFVIGVGGVGGALLEQLKRQQTWLKNKHIDLRVCGVANSKA
                     LLTNVHGLNLDNWQAELAQANAPFNLGRLIRLVKEYHLLNPVIVDCTSSQAVADQYAD
                     FLREGFHVVTPNKKANTSSMDYYHQLRFAAAQSRRKFLYDTNVGAGLPVIENLQNLLN
                     AGDELQKFSGILSGSLSFIFGKLEEGMSLSQATALAREMGYTEPDPRDDLSGMDVARK
                     LLILARETGRELELSDIVIEPVLPDEFDASGDVTAFMAHLPQLDDAFAARVAKARDEG
                     KVLRYVGNIEEDGVCRVKIAEVDGNDPLFKVKNGENALAFYSHYYQPLPLVLRGYGAG
                     NDVTAAGVFADLLRTLSWKLGV"
     gene            5625..6554
                     /gene="thrB"
                     /locus_tag="OPV72_002942"
     CDS             5625..6554
                     /gene="thrB"
                     /locus_tag="OPV72_002942"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HCR9915178.1"
                     /translation="MVKVYAPASSANMSVGFDVLGAAVTPVDGTLLGDVVSVEAADHF
                     RLHNLGRFADKLPPEPRENIVYQCWERFCQALGKTIPVAMTLEKNMPIGSGLGSSACS
                     VVAALVAMNEHCGKPLNDTRLLALMGELEGRISGSIHYDNVAPCFLGGMQLMIEENGI
                     ISQQVPGFDEWLWVLAYPGIKVSTAEARAILPAQYRRQDCIAHGRHLAGFIHACYSRQ
                     PQLAAALMKDVIAEPYRARLLPGFSQARQAVSEIGALASGISGSGPTLFALCDKPETA
                     QRVADWLSKHYLQNQEGFVHICRLDTAGARVVG"
     gene            6558..7844
                     /gene="thrC"
                     /locus_tag="OPV72_002943"
     CDS             6558..7844
                     /gene="thrC"
                     /locus_tag="OPV72_002943"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HCR9915179.1"
                     /translation="MKLYNLKDHNEQVSFAQAVTQGLGKQQGLFFPHDLPEFSLTEID
                     EMLNQDFVSRSAKILSAFIGDEIPQQILEERVRAAFAFPAPVAQVESDVGCLELFHGP
                     TLAFKDFGGRFMAQMLTHISGDKPVTILTATSGDTGAAVAHAFYGLENVRVVILYPRG
                     KISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDEELKTALGLNSANSINISR
                     LLAQICYYFEAVAQLPQGARNQLVISVPSGNFGDLTAGLLAKSLGLPVKRFIAATNIN
                     DTVPRFLHDGKWAPKATQATLSNAMDVSQPNNWPRVEELFRRKIWRLTELGYAAVDDT
                     TTQQTMRELKAKGYISEPHAAVAYRALRDQLNPGEYGLFLGTAHPAKFKESVESILGE
                     TLALPEALAERADLPLLSHHLPADFAALRKLMMTRQ"
     gene            complement(7938..8711)
                     /gene="yaaA"
                     /locus_tag="OPV72_002944"
     CDS             complement(7938..8711)
                     /gene="yaaA"
                     /locus_tag="OPV72_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HCR9915180.1"
                     /translation="MLILISPAKTLDYQSPLATTRYTQPELLDHSQQLIQQARQLSAP
                     QISRLMGISDKLADLNATRFHDWQPHFTPDNARQAILAFKGDVYTGLQAETFNDADFD
                     FAQQHLRMLSGLYGVLRPLDLMQPYRLEMGIRLENPRGKDLYQFWGDIITDKLNEALE
                     AQGDRVVVNLASEEYFKSVKPKKLDAELIKPVFLDEKNGKFKVVSFYAKKARGLMSRF
                     IIENRLTKPEQLTAFDREGYFFDEETSTQDELVFKRYEQ"
     gene            complement(8790..10220)
                     /locus_tag="OPV72_002945"
     CDS             complement(8790..10220)
                     /locus_tag="OPV72_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HCR9915181.1"
                     /translation="MPEFFSFINEILWGSVMIYLLLGAGCWFTWRTGFIQFRYIRQFS
                     RSLKGSLSPQPGGLTSFQALCTSLAARIGSGNLAGVALAIAAGGPGAVFWMWVSAIIG
                     MATSFAECSLAQLYKERDPTGQFRGGPAWYMARGLGMRWMGVVFALFLLVAYGLIFNS
                     VQANAVSRALHFAFNIPPLISGIALAFCALLIIIRGIKGVARLMQWLIPLIALLWVAG
                     SVFICLWHIEQMPGVIASIVKSAFGWQEAAAGAAGYTLTQAITSGFQRGMFSNEAGMG
                     STPNAAAAATSYPPHPVAQGIVQMIGVFSDTIIICTASAMIILLAGNHASHSSTEGIQ
                     LLQHAMVSLTGEWGASFVALIVILFAFSSIVANYIYAENNLFFLRLHNAKAIWLLRLA
                     TLGMVIAGTLISFPLIWQLADMIMACMAITNLTAILLLSPVVYTLAGDYLRQRKLGVR
                     PQFDPRRFPDIEPQLAPDTWDAASRD"
     gene            10489..11442
                     /gene="tal"
                     /locus_tag="OPV72_002946"
     CDS             10489..11442
                     /gene="tal"
                     /locus_tag="OPV72_002946"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase"
                     /protein_id="HCR9915182.1"
                     /translation="MTDKLTSLRQFTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQ
                     IPEYRKLIDDAVAWAKQQSSDRAQQVVDATDKLAVNIGLEILKLVPGRISTEVDARLS
                     YDTEASIAKAKRIIKLYNDAGISNDRILIKLASTWQGIRAAEQLEKEGINCNLTLLFS
                     FAQARACAEAGVYLISPFVGRILDWYKANTDKKDYAPAEDPGVVSVTEIYEYYKQHGY
                     ETVVMGASFRNVGEILELAGCDRLTIAPALLKELAESEGAIERKLSFSGEVKARPERI
                     TEAEFLWQHHQDPMAVDKLADGIRKFAVDQEKLEKMIGDLL"
     gene            11553..12143
                     /gene="mog"
                     /locus_tag="OPV72_002947"
     CDS             11553..12143
                     /gene="mog"
                     /locus_tag="OPV72_002947"
                     /EC_number="2.7.7.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin adenylyltransferase"
                     /protein_id="HCR9915183.1"
                     /translation="MNTLRIGLVSISDRASSGVYQDKGIPALEEWLASALTTPFELQT
                     RLIPDEQAIIEQTLCELVDEMSCHLVLTTGGTGPARRDVTPDATLAIADREMPGFGEQ
                     MRQISLRFVPTAILSRQVGVIRKQALILNLPGQPKSIKETLEGVKADDGSVSVPGIFA
                     SVPYCIQLLDGPYVETAPEVVAAFRPKSARRENMSS"
     gene            complement(12200..12766)
                     /gene="satP"
                     /locus_tag="OPV72_002948"
     CDS             complement(12200..12766)
                     /gene="satP"
                     /locus_tag="OPV72_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate uptake transporter"
                     /protein_id="HCR9915184.1"
                     /translation="MGNTKLANPAPLGLMGFGMTTILLNLHNAGFFALDGIILAMGIF
                     YGGIAQIFAGLLEYKKGNTFGLTAFTSYGSFWLTLVAILLMPKMGLTDAPDAQLLGAY
                     LGLWGVFTLFMFFGTLKAARALQFVFLSLTVLFALLAVGNITGNEATIHIAGWVGLVC
                     GASAIYLAMGEVLNEQFGRTILPIGEAH"
     gene            complement(12916..13629)
                     /gene="msyB"
                     /locus_tag="OPV72_002949"
     CDS             complement(12916..13629)
                     /gene="msyB"
                     /locus_tag="OPV72_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acidic protein MsyB"
                     /protein_id="HCR9915185.1"
                     /translation="MNVTYLHDEDLDFLQHCSEEQLADFARLLTHNEKGKARLSSVLS
                     HNELFKAMEGHPEQHRRNWQLIAGEFQHYGGDSIANKLRGHGKQYRAILLDVAKRLKL
                     KADKSMSTFEIEQQLLEHFLRHTWQKMDAAHKQEFLQAVDAKVSELEELLPLLMKDRS
                     LAKGVSHLLSTQLTRILRTHAAMSILGHGLLRGAGLGGPVGAALNGVKAMSGSAYRVT
                     IPAVLQIACLRRMMAAVQA"
     gene            complement(13665..14069)
                     /locus_tag="OPV72_002950"
     CDS             complement(13665..14069)
                     /locus_tag="OPV72_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2541 family protein"
                     /protein_id="HCR9915186.1"
                     /translation="MRSVLTISVGLLFGLALSSVAHANDHKILGVIAMPRNETNDLAL
                     KIPVCRIVKRIQLTADHGDIELSGASVYFKTARSASQSLNVPSSIKEGQTTGWININS
                     DNDNKRCVSKITFSGHTVNSSDMARLKVIGDD"
BASE COUNT         3414 a         3609 c         3850 g         3251 t
ORIGIN      
        1 tcattttatg acagctatca taggtaccgt gcttaacgag cgcgtagagc gtacaggata
       61 gcgaagcgat gaacatcgct gttggaggat acgaatgaga gaaaagtaca aaatgcaagc
      121 gggcggcgtt ttactgagcg aaatcgccgc ctgccggaac tcctcccgtc gggagccata
      181 agcggttagc ggtactggac gatcaggctt tgaatctccg gatgatcttt taacgacacg
      241 tgccgtaccg tggcgattcc attcatcaac gaaatagcgt ttccagacgg tgtggcgact
      301 gtctgcaaat gggggattcc gcaaacatga tacctcgata ttgcgatcgt gaggcgcaag
      361 attacaacca tattcgacaa tctggccttt gaaatgaata acgcctgcgg agaccggcgc
      421 ggtagcagcc agcgcggctg atgaagctga catcgctgca caaaacaggt agcagcataa
      481 tggtgatttt ttcatcctgt gaaacctcac gtcctgtgag catcccctta atttttgggg
      541 accaacaaat cccgtgtatt actctttaat gtaaatacac aaactacctt aactttcgca
      601 agctgagata aacagcgcta tacgacaatt tttatgtaaa agagtacgtc ataacggcag
      661 gtcaggaggg aaagcggggc cgcttagcgg aaggggagca taagaaacag ccagtaagaa
      721 taacttaccg gctgttttta cggtttggcg cctgggccga attaatcctg caggtcgccg
      781 cagaagcgat aaccttcgcc gtgaatggtg gcgatgattt ccggcgtatc cggcgtggat
      841 tcgaaatgct tacgaatacg acgaatggtg acgtcaacag tacggtcatg cggcttcagc
      901 tcgcgtccgg tcattttttt cagcagctcg gcacgagact gaattttgcc agggttttcg
      961 cagaagtgca gcatcgcgcg gaactcgctg cgcggtagtt tatactgctc gccgtccggg
     1021 ccgatcagtg aacggctgtt gatatccagt tcccaaccgt tgaacttata gctttcaacg
     1081 ctacgacgct cttcgctgac ggtacccagg ttcatggtac gggacagcag gttacgggca
     1141 cggatggtca attcgcgtgg attaaacggt ttggtgatgt aatcatccgc gccgatttcg
     1201 aggccgagaa ttttgtcgac ttcgttatcg cggcccgtca ggaacatcag cgcaacatta
     1261 gcctgctcac gcagttcacg cgctaacagg agaccgtttt tccctggcag attgatatcc
     1321 atgatcacca ggttgatgtc atattcagag aggatctgat gcatttccgc gccatctgtc
     1381 gcttcgaata catcatagcc ttccgcttcg aaaatacttt tcaacgtgtt gcgtgttacc
     1441 aactcgtctt caacgataag aatgtgcggg gtctgcatgt ttgctaccta aattgccaac
     1501 taaatcgaaa caggaagtac aaaagtccct gacctgcctg atgcatgtcg caaattaaca
     1561 tgatcggcgt aacatgacta aagtacgtaa ttgcgttctt gatgcacttt ccatcaacgt
     1621 caacaacatc attagcttgg tcgtgggtac tttccctctg gacccgacag tgtcaaaaac
     1681 ggctgtcatc ctaaccattt taacagcaac ataacaggct aagacgtacc ggacacctaa
     1741 taaaactacg cttcgttgac atatatcaag ttcaattgta gcacgttaac agtttgatga
     1801 aatcatcgta gctaaatgct agctttcatc acaaatttgc aatattccaa ctagttacgt
     1861 aagccaacta ataaatgcga tgaatccaaa gaacaggatc tattttaaat taaattatcc
     1921 taaataaaca gcaggataac gatgttctgt taacataaac agcaatagta cagatacgca
     1981 atagtgtagc gtcttttacg aaatcaaaaa tgctttttca gtgatatccg ttaaaatttt
     2041 gtaaatttgc gaagcgtaat atgcttacaa acgccagcta atttcctgta aattagtcaa
     2101 aaagagtaat gaaatgcgtg taacaatcgt tcttgtcgct cccgccagag cggaaaatat
     2161 cggcgcagcc gcccgggcta tgaagaccat gggatttact gacctgcgta ttgtcgacag
     2221 ccaggcgcac ctagagcccg ctacccgttg ggtcgcacat ggatctggag atattattga
     2281 taatattgag gttttccaca cccttgccga cgcgctccac gatgtggatt ttaccgtagc
     2341 gacgacagcc cgcagccggg caaaatttca ttactacgct tcgcccgctg aactggttcc
     2401 cttattacag gaaaaatcac gctggatgcg tcatgccgcg ctggtttttg gccgtgagga
     2461 ttccggtctg accaacgacg agctggcgct ggcggatgta ttgaccggcg tgccgatggc
     2521 ggcggattac ccttcgctca atctgggtca ggcggtcatg gtgtattgct atcaattagc
     2581 aggtttaatg caacagaccc cggaatccgt tgatattgct gatgaatcgc agttacaggc
     2641 gttacgcgcg cgccttttac gcctgctaac cactctggag gcggccgatg accacaaatt
     2701 aaccgactgg ctacaacagc gaatcggcct gctgggacag cgagatacgg caatgttgca
     2761 ccgtttggtc catgatattg aaaaaaaact aacaaaataa cgtgttgtaa tttttaaaat
     2821 aataagagat tacgtctggt tgcaagagat cataacaggg gaaattgatt gaaaataaat
     2881 atatcgccag cagcacatga acaagtttcg gaatgtgatc aatttaaaaa tttattgact
     2941 taggcgggca gatactttaa ccaatatagg aatacaagac agacaaataa aaatgacaga
     3001 gtacacaaca tccatgaacc gcatcagcac caccaccatt accaccatca ccattaccac
     3061 aggtaacggt gcgggctgac gcgtacagga aacacagaaa aaagcccgca cctgaacagt
     3121 gcgggctttt ttttcgacca gagatcacga ggtaacaacc atgcgagtgt tgaagttcgg
     3181 cggtacatca gtggcaaatg cagaacgttt tctgcgtgtt gccgatattc tggaaagcaa
     3241 ttccaggcaa gggcaggtag cgaccgtact ttccgccccc gcgaaaatta ccaaccatct
     3301 ggtggcgatg attgaaaaaa ctatcggcgg ccaggatgct ttgccgaata tcagcgatgc
     3361 cgaacgtatt ttttctgacc tgctcgcagg acttgccagc gcgcagccgg gattcccgct
     3421 tgcacggttg aaaatggttg tcgaacaaga attcgctcag atcaaacatg ttttgcatgg
     3481 tatcagcctg ctgggtcagt gcccggatag catcaacgcc gcgctgattt gccgtggcga
     3541 aaaaatgtcg atcgcgatta tggcgggact cctggaggcg cgtggacatc gcgtcacggt
     3601 gatcgatccg gtagaaaaac tgctggcggt gggccattac cttgaatcta ccgtcgatat
     3661 cgcggaatcg actcgccgta tcgccgccag ccagatcccg gccgatcaca tgatcctgat
     3721 ggcgggcttt actgccggta atgaaaaggg tgaactggtg gtgctgggcc gtaatggttc
     3781 cgactattcc gccgccgtgc tggccgcctg tttacgcgct gactgctgtg aaatctggac
     3841 tgacgtcgat ggcgtgtata cctgtgaccc gcgccaggtg ccggacgcca ggctgttgaa
     3901 atcgatgtcc taccaggaag cgatggagct ctcttacttc ggcgctaaag tccttcaccc
     3961 tcgcaccata acgcctatcg cccagttcca gatcccctgt ctgattaaaa ataccggcaa
     4021 tccgcaggcg ccaggaacgc tgatcggcgc gtccagcgac gatgataatc tgccggttaa
     4081 agggatctct aaccttaaca acatggcgat gtttagcgtc tccggcccgg gaatgaaagg
     4141 gatgattggg atggcggcgc gtgttttcgc cgccatgtct cgcgccggga tctcggtggt
     4201 gctcattacc cagtcctcct ctgagtacag catcagcttc tgtgtgccgc agagtgactg
     4261 cgcgcgtgcc cgccgtgcga tgcaggatga gttctatctg gagctgaaag aggggctgct
     4321 ggagccgctg gcggttacgg agcggttggc gattatctct gttgtcggcg acggtatgcg
     4381 cacgctacgc ggcatttcag cgaaattctt cgccgcgctg gcgcgggcta atatcaatat
     4441 cgtggcgatc gctcagggat cttctgagcg ttccatttct gtggtggtga ataacgacga
     4501 tgccaccacc ggcgtgcggg taacgcacca gatgctgttc aataccgatc aggtgattga
     4561 agtgtttgtc attggcgtcg gcggcgtcgg cggcgcgcta ctggaacagc ttaaacgtca
     4621 gcaaacctgg ctgaagaaca agcacatcga tctacgcgtg tgcggcgtgg cgaactcaaa
     4681 ggcgttgcta accaatgtgc atggcctgaa tctggacaac tggcaggcgg aactggcgca
     4741 agcgaacgcg ccgttcaatc tgggacgttt aattcgcctg gtgaaagaat atcatctact
     4801 caatccggtg attgttgatt gtacctccag tcaggcggtg gccgaccagt atgccgactt
     4861 cctgcgcgaa gggttccatg tggtgacgcc gaacaagaaa gcgaacacct cgtcgatgga
     4921 ctactaccat cagctacgtt tcgccgccgc gcaatcacgg cgcaaattct tgtatgacac
     4981 caacgtcggc gccggtttgc cggtaatcga aaacctgcaa aacctgctga atgcgggtga
     5041 tgaactgcaa aaattttccg gcattctttc cgggtcgctc tcttttattt tcggtaaact
     5101 ggaagagggg atgagtctct cacaggcgac cgctctggcg cgcgagatgg gctataccga
     5161 acccgatccg cgcgacgatc tttccggtat ggatgtggcg cgtaaactgt tgatcctcgc
     5221 ccgcgagacg ggccgcgagc tggagctttc cgatatcgtg attgaaccgg tgttgccgga
     5281 cgagtttgac gcctccggcg atgtgaccgc ctttatggcg catctgccgc agcttgacga
     5341 cgcgtttgcc gcccgtgtgg cgaaagctcg tgatgaaggt aaggtattgc gctatgtggg
     5401 caatatcgaa gaggatggcg tgtgccgcgt gaagattgcc gaagttgatg gtaacgatcc
     5461 gctcttcaaa gtgaaaaacg gtgaaaacgc gctggcgttc tacagccatt attatcagcc
     5521 cttgccgttg gtgctgcgcg gctacggcgc aggcaatgat gtgacggcgg cgggcgtgtt
     5581 tgccgatctg ttacggaccc tctcatggaa gttaggagtt taacatggtg aaagtgtatg
     5641 ccccggcttc cagcgcgaac atgagcgtcg gtttcgacgt gttgggcgcg gccgtcacac
     5701 ccgttgacgg cacgttgctg ggcgatgtgg tatccgttga agcagcggat catttccgtc
     5761 tgcataacct ggggcgattt gccgataaac tgccgccgga gccgcgtgaa aatattgttt
     5821 atcagtgctg ggaacgtttt tgccaggcat tggggaaaac catcccggtg gcgatgacgc
     5881 tggaaaaaaa tatgccgatt ggttccgggt tagggtccag cgcctgttcc gtcgtcgccg
     5941 cgctggtcgc gatgaatgag cactgcggca aaccgttaaa cgacacgcgt ctgttggcgc
     6001 tgatgggcga gctggaaggc cgtatctccg gcagcatcca ttacgataac gtcgcgccgt
     6061 gctttcttgg cggtatgcag ttgatgattg aagaaaacgg cattattagt cagcaggtgc
     6121 cgggctttga tgagtggcta tgggtactgg cttatccggg cattaaagtt tccaccgcag
     6181 aagcacgggc cattttgcct gcgcagtatc gccgtcagga ttgcattgcg catggacggc
     6241 atctggccgg ttttattcac gcctgttact cgcggcagcc gcagcttgcc gccgcgctga
     6301 tgaaagatgt tattgccgaa ccataccgcg cgcgtttact gccgggcttt agccaggcgc
     6361 ggcaggcggt gtcggagatc ggcgcgctgg cgagcgggat ttccggatcg gggccgacgc
     6421 tgtttgcgct atgcgataaa ccggagacgg cgcagcgcgt cgcggactgg ctgagcaaac
     6481 attatctgca aaatcaggaa ggcttcgttc atatttgtcg gctggatacg gcgggcgcac
     6541 gagtagtggg ataatcaatg aaactctata atctgaaaga ccataatgag caggtcagct
     6601 ttgcgcaggc cgtcacgcaa gggctgggca aacagcaggg actttttttt ccgcacgatc
     6661 tgccggagtt tagcctgacg gaaattgatg agatgctcaa ccaggacttt gtcagccgta
     6721 gcgcaaagat cctctcggca tttattggcg atgaaatacc gcagcaaatt ctggaagagc
     6781 gcgtccgcgc ggcgtttgct ttcccggcgc cggtagcgca ggtagaaagt gatgtcggct
     6841 gcctggagct gttccatggt ccgacgctgg cctttaaaga cttcggcggg cgttttatgg
     6901 cgcaaatgct gacgcatatc agcggcgata aaccggtgac gattctgacc gcaacgtcag
     6961 gcgataccgg cgcggcggtg gctcacgcgt tctatggcct ggaaaatgtg cgggtcgtca
     7021 ttctctaccc gcgcggtaaa atcagtccgt tgcaggaaaa actgttctgt acgctgggcg
     7081 gcaacattga gaccgtggcg atcgacggcg atttcgacgc ttgccaggcg ctggtgaaac
     7141 aggcatttga tgacgaagaa ctgaaaacgg cgctggggtt gaattcggct aattcgatta
     7201 atatcagccg cctgctggcg caaatttgct actactttga agccgtggcg caactgccgc
     7261 agggggcgcg taaccaactg gtgatctccg tacccagcgg caactttggc gatttgacgg
     7321 caggactgct ggcgaagtcg ttaggcctac cggtgaaacg ctttatcgcc gccaccaaca
     7381 ttaacgatac ggtgccgcgt tttctgcatg acgggaagtg ggcgccaaaa gcgacgcagg
     7441 cgaccctgtc gaatgcgatg gatgtcagcc agccgaataa ctggccgcgt gtggaggagc
     7501 tattccgccg taaaatctgg cgtctgactg agctgggcta tgcggcggtg gatgacacta
     7561 cgacacaaca gacgatgcgc gagctgaaag cgaaaggtta tatctcggaa cctcatgcgg
     7621 cggtagcgta tcgggcatta cgcgaccagt taaaccctgg cgagtatggc ttgtttctcg
     7681 gaacggcgca tccggcgaag tttaaagaaa gcgtggagtc cattctggga gaaacgctgg
     7741 cattgcctga agcgctcgcc gaacgcgccg atctgccgtt gctttcacat catctgcctg
     7801 cggattttgc cgccctgcgt aagctaatga tgacccgcca gtaaccattg cgcccggtgg
     7861 cgctgtcgct taccgggcct atggggtggt gccgatttgt aggccggata aggcgtaacc
     7921 gccatccggc gatgtcgtta ctgctcgtag cgtttaaaga ccagctcgtc ttgtgtggag
     7981 gtttcttcat caaagaaata cccttcacgg tcaaacgcgg taagctgttc cggcttcgtt
     8041 aagcggtttt caataataaa acgactcatc agtccgcgcg cttttttggc gtagaagctt
     8101 accaccttaa acttgccgtt tttctcatca aggaatacgg gcttaatcag ttcggcatcc
     8161 agtttcttcg gcttcaccga tttaaaatat tcctcggagg ccagattcac caccacccga
     8221 tcgccctgcg cctcaagcgc ttcgttgagc ttatcggtaa tgatatcgcc ccagaattga
     8281 taaagatctt tgccgcgcgg attctccagg cgaatcccca tctccagacg ataaggctgc
     8341 attaaatcca gcgggcgcaa tacgccatac aagccagaga gcatacgcag atgttgttga
     8401 gcaaaatcaa aatccgcgtc gttgaacgtt tccgcctgta ggccggtata aacatcgcct
     8461 ttgaacgcca gaatcgcctg gcgtgcatta tccggcgtaa aatgaggctg ccagtcatga
     8521 aaacgcgtgg cgttgagatc cgccagtttg tcgctaattc ccattagcct ggaaatttgc
     8581 ggcgccgaaa gctggcgggc ctgttgaata agctgctggc tgtgatccaa cagctccggc
     8641 tgggtatagc gggtcgtggc cagcgggctt tgataatcaa gcgtttttgc aggtgaaatc
     8701 agaatcagca tatccagtcc ttgcagggaa ttttctgcga ctttagcaaa aaaacgccgc
     8761 agagttgacc gatggttgcg attgtcggct taatcgcgcg atgccgcatc ccaggtatct
     8821 ggcgccagtt gtggttcgat atccgggaag cgccgcggat cgaactgcgg tcttacgccc
     8881 agtttccgtt gtcgcagata atcgccggcg agggtataca ccaccggtga gagcaacaaa
     8941 atcgccgtca gattggtaat ggccatacag gccatgatca tgtcagcgag ctgccatatc
     9001 agcggaaaac tgataagcgt accggcgatg accatgccaa gcgtcgcaag acgtaatagc
     9061 cagatggcct ttgcgttatg taaccgcaga aaaaagagat tgttttcggc gtaaatatag
     9121 ttggcgacga tagaactgaa cgcgaacaga atgacgataa gcgcgacaaa actggcgccc
     9181 cattcaccgg tcaacgaaac cattgcatgt tggagaagct gaatgccttc tgttgacgaa
     9241 tgggacgcgt gattccccgc cagcaggata atcatcgcgc tggcggtaca gatgataatg
     9301 gtgtcgctga atacgccaat catttgcaca atcccctgcg cgacagggtg agggggatac
     9361 gacgttgccg ctgcggccgc attaggcgtt gaccccattc ccgcttcatt agagaacatc
     9421 ccacgctgaa aaccgctggt aatagcctgg gtgagcgtat atccggctgc gcctgccgcg
     9481 gcttcctgcc agccaaatgc gcttttgact atcgaggcga taacgccagg catttgctca
     9541 atatgccaga ggcaaatgaa tacgctgcca gcgacccaca ataacgcgat gaggggaatc
     9601 agccattgca tcaggcgggc gacgcctttt atgccgcgga tgataattaa cagggcacag
     9661 aacgccaaag caatgccgga gataagcggc ggaatgttga aggcgaaatg gagcgcgcgt
     9721 gagacggcat tcgcctgcac gctattaaaa atcaacccgt aggcgacgag cagaaagagg
     9781 gcgaaaacca cgcccatcca gcgcattccc agcccgcgcg ccatatacca cgccgggccg
     9841 ccgcggaact ggcctgtcgg gtcacgttct ttataaagct gggcaagcga acactcggcg
     9901 aaggaggtcg ccataccaat gatggccgag acccacatcc agaatactgc gccgggaccg
     9961 cctgcggcga tagccagcgc cacgccggcc agattaccgc tgccaatccg cgccgcgagg
    10021 ctggtacaca gcgcctgaaa tgacgtcagg ccgcctggct gcgggctaag gctgcctttc
    10081 agactgcggc taaattggcg aatataacga aactgaatga atccggtacg ccaggtaaac
    10141 caacatcctg cgccgagcag caggtaaatc attaccgagc cccagagtat ttcgttaata
    10201 aaactgaaaa actcaggcat taacgtccct cttgttgatg ccgacacgct ttgatgatcc
    10261 tgtataagcg tgacccatga tgtagatgac cttgtcaggc taatattaac ggtagtttac
    10321 cataaatacg gcggtatcct ttaattgcgc atcaaccgtc ggcagatacg caaacagttc
    10381 acaagggcag ccaggtgcat gtaggcggtt gcgctgtgag tgcgtcgtgt tatcatcagg
    10441 gtagaccggt tacatcccct aacaagctgt ttaaagagaa actctatcat gacggacaaa
    10501 ttgacctccc ttcgtcagtt caccaccgta gtggctgata ccggagatat cgcggcaatg
    10561 aagctgtacc agccgcagga tgctacaact aacccttctc tcattcttaa cgcagcgcaa
    10621 atcccggaat atcgtaagct gattgacgat gctgtcgcct gggcgaaaca gcagagcagc
    10681 gaccgcgcgc agcaggttgt tgacgcgacc gataagctgg cggtgaatat tggcctggaa
    10741 atcctgaagc tggtgccggg gcgtatttct accgaagttg acgcgcgtct atcttatgac
    10801 actgaagcgt ctatcgccaa agcaaaacgt atcattaaac tctacaatga tgcgggtatc
    10861 agcaacgatc gtatcctgat caagctggcg tccacctggc agggcattcg cgcagccgaa
    10921 cagctggaaa aagaaggcat caactgtaac ctgacgctgc tgttctcctt cgcgcaggcg
    10981 cgtgcgtgcg ccgaagcggg cgtctacctg atctcgccgt tcgtaggtcg tattcttgac
    11041 tggtataaag ccaataccga caagaaagac tatgcgccag ctgaagatcc gggcgtggtt
    11101 tccgtaacgg aaatctacga gtactacaaa cagcatggtt acgaaaccgt cgttatgggc
    11161 gcaagcttcc gtaacgtagg cgaaattctg gagctggcgg gctgcgaccg tctgactatc
    11221 gcgccggcat tgctgaaaga actggcggaa agcgaagggg cgattgagcg taagctctct
    11281 ttctccggcg aagtcaaagc gcgtccggaa cgtattaccg aagccgagtt cctgtggcag
    11341 catcaccagg accctatggc ggttgacaaa ctggcggatg gtatccgtaa gtttgcggta
    11401 gaccaggaaa aactggaaaa aatgatcggc gatctgctgt aatcattaac gcgtggccct
    11461 gatatgggtc acgctacctc ttctgaaacc tgtctgtcct tcctttcgca gtgtatcatt
    11521 ctgtttaacg agactgttta aacggaataa tcatgaatac tttacgcatt ggcctggttt
    11581 ccatttctga ccgtgcttcc agcggcgttt accaggataa aggtatcccg gcccttgaag
    11641 agtggctggc atctgccctt accacccctt ttgagctgca aacgcgactg atcccggatg
    11701 aacaggcgat catcgaacag accttatgtg aactggttga tgagatgagc tgtcatctgg
    11761 tgctgaccac tggcggtacc ggtccggcac gtcgcgacgt cacgccggac gcgacccttg
    11821 ccatcgccga ccgtgaaatg cctggttttg gcgaacagat gcgccagatc agcctgcgct
    11881 ttgtgccgac cgccattctt tcccgccagg tgggcgttat ccgtaaacag gcgttaattc
    11941 ttaatctgcc tggacagcca aaatcgatca aagaaacgct ggaaggcgta aaagcggacg
    12001 atggcagcgt tagcgtgccg ggcatttttg cgagcgtgcc gtattgcata cagctgcttg
    12061 acgggccgta tgtcgaaacc gcgccggaag tggttgccgc tttccgtcca aagagcgcca
    12121 gacgtgagaa tatgtcgtcc tgaccgggag atactgatag tagggttatt cctcccggtg
    12181 cgggaggaat aaaagagatt tagtgcgcct cgccgattgg caaaatagtg cggccaaatt
    12241 gctcgtttag cacttcaccc atcgccagat aaatagcgct ggcgccgcaa accagaccaa
    12301 cccagcctgc gatatggata gttgcttcgt taccggtgat attgccgacc gccagcagag
    12361 cgaacagtac ggtcaggctc aggaaaacaa attgcagcgc gcgggcggct ttcagcgtac
    12421 cgaagaacat aaacagcgtg aacacgcccc acagacctaa ataagcgccg agtagctgag
    12481 cgtcaggcgc atccgtcagg cccattttcg gcatcagcag gatagcgacc agcgtcagcc
    12541 agaacgaacc gtaagaagta aaggccgtta aaccaaaggt attgcctttt ttatactcca
    12601 gcagaccggc aaaaatttgc gcgataccgc cgtagaaaat ccccatcgcc agaataatac
    12661 cgtccagggc gaaaaaaccg gcattgtgca ggttaagcag aatggtggtc atgccgaagc
    12721 ccatcaggcc cagcggtgcc ggattagcca acttagtgtt gcccataatt cctcaaaatc
    12781 atcataattg aatggtgaaa tagtttccca gaataacgag ttccgtattc ggggcgcggc
    12841 ataataatca gggggaagag gactgtctat gatctaataa gggggaaaag aaaatatttc
    12901 cccctgtgag ggcattcacg cctgaacggc tgccatcatt cgtcgcaggc aggctatttg
    12961 caagaccgcc ggaatagtca cgcgatacgc gctgccgctc atcgctttga cgccgtttaa
    13021 tgccgcgccg accgggccgc caagacctgc gccgcgcagc aatccgtggc ccaggatgct
    13081 cattgcggca tgggtacgta aaatgcgggt aagctgggtg gaaagcaggt gggagacccc
    13141 ttttgccaga ctgcgatctt tcatgagcag cggcagcagt tcttccagtt cagaaacttt
    13201 ggcgtctacg gcttgcagaa attcctgctt atgcgccgcg tccatcttct gccaggtatg
    13261 acgtaaaaaa tgctccagca gttgctgttc tatttcaaac gtcgacatgc ttttatctgc
    13321 tttaagtttt agccgttttg cgacatccag cagaatcgcg cggtactgtt ttccgtgtcc
    13381 gcgcaatttg ttggcgatac tgtcgccgcc gtaatgctga aactcgccgg caatgagctg
    13441 ccagttacgg cggtgttgct ccgggtgacc ttccatcgct ttgaacagct cgttatgact
    13501 aaggacgctc gacaagcgag ctttgccctt ttcgttatgc gtcagcaaac gggcgaaatc
    13561 ggcgagttgt tcttcgctac aatgctgaag aaagtctaaa tcctcgtcgt gtaaataggt
    13621 gacgttcatt ttcagtctgg cttttggaat agaaataaca gcgattaatc gtcgccaatg
    13681 actttaagtc tcgccatatc ggaagaattt accgtatgac ctgagaaggt aatctttgat
    13741 acgcagcgtt tgttgtcgtt atcgctatta atattgatcc agcctgtcgt ctggccttct
    13801 ttgattgagg aagggacgtt caggctttgg ctggcgctac gcgcagtttt aaaatagacg
    13861 gatgcgccgc taagttcgat atcgccgtga tccgccgtga gttgaatgcg cttcacgatg
    13921 cggcagacgg gaattttcag cgcgagatcg ttcgtttcat ttctgggcat ggcaataaca
    13981 cccagtattt tatggtcgtt cgcgtgcgcg acgctactta acgccaggcc gaaaagcagg
    14041 ccgacggaaa tcgttaacac agatcgcatg aaatttctct ttgacgggtt caataagcaa
    14101 ttaccgtcta tcatactctg ctca
//
LOCUS       DAJVBX010000120        14044 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.120, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000120 DAJVBX010000000
VERSION     DAJVBX010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 14044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14044
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.120"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            46..1473
                     /locus_tag="OPV72_002951"
     CDS             46..1473
                     /locus_tag="OPV72_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent transcriptional regulator"
                     /protein_id="HCR9915187.1"
                     /translation="MASTNQELASALRMFSRFFDLIHQPLAVINERGEYVYYNQESAD
                     LDGYSIERAMGKHMLDVYPGMKETQSTMLSSLKKGVEYIGHYQIYYNARGQAVDYQHT
                     TASLYASDGGMVGVIEIGRNMSGVRRLQEQVVELNQLLYADHHEKHHAIITENPEMLS
                     NIAKAKRLAASNIPVTIVGETGTGKELFSRLIHQCSKRANKPFIALNCGALPPTLIES
                     TLFGTVRGAYTGAENSQGYLELANGGTLFLDELNAMPIEMQSKLLRFLQDKTFWRLGG
                     QQQLHSDVRIVAAMNEAPVKLIQQERLRADLFYRLSVGMLTLPPLRARPEDIPLLANY
                     FIDKYRNDVPQDIHGLSETARADLLNHAWPGNVRMLENAIVRSMIMQEKDGLLKHIIF
                     EQDELNLGVPETAPENPLPSSPDPQYEGSLEVRVANYERHLIETALDTHQGNIAAAAR
                     SLNVSRTTLQYKVQKYAIRFGVVRN"
     gene            complement(1509..3026)
                     /gene="purF"
                     /locus_tag="OPV72_002952"
     CDS             complement(1509..3026)
                     /gene="purF"
                     /locus_tag="OPV72_002952"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006820991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HCR9915188.1"
                     /translation="MCGIVGISGVMPVNQSIYDALTVLQHRGQDAAGIITIDANNCFR
                     LRKANGLVNDIFEARHMQRLQGNMGIGHVRYPTAGSSSASEAQPFYVNSPYGITLAHN
                     GNLTNAHELRKKLFEEKRRHINTTSDSEILLNIFASELDSFRHYPLEADNIFAAIAAT
                     NRQIRGAYACVAMIIGHGMVAFRDPHGIRPLVLGKRDVGDGRTEYMVASESVALDTLG
                     FEFLRDVAPGEAIYITEKGQLFTRQCADNPVSNPCLFEYVYFARPDSFIDKISVYSAR
                     VNMGTKLGEKIAREWEDLDIDVVIPIPETSCDIALEIARILGKPYRQGFVKNRYVGRT
                     FIMPGQQLRRKSVRRKLNANRAEFRDKNVLLVDDSIVRGTTSEQIIEMAREAGAKKVY
                     LASAAPEIRFPNVYGIDMPTANELIAHGREVDEIRQIIGADGLIFQDLNDLIEAVRAE
                     NPDIQQFECSVFNGVYVTKDVDQQYLDFLDSLRNDDAKAVLFQNEMENLEMHNEG"
     gene            complement(3064..3552)
                     /gene="cvpA"
                     /locus_tag="OPV72_002953"
     CDS             complement(3064..3552)
                     /gene="cvpA"
                     /locus_tag="OPV72_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin V production protein"
                     /protein_id="HCR9915189.1"
                     /translation="MVWIDYAIIAVIAFSCLVSLIRGFVREALSLVTWGCAFFVASHY
                     YTYLSVWFTGFEDELVRNGIAIAVLFIATLIVGAIVNFVIGQLVEKTGLSGTDRVLGI
                     CFGALRGALIVAAILFFLDTFTGLSKSEDWSKSQLIPQFSFIIRWFFDYLQSSSSFLP
                     RT"
     gene            complement(3863..4537)
                     /gene="dedD"
                     /locus_tag="OPV72_002954"
     CDS             complement(3863..4537)
                     /gene="dedD"
                     /locus_tag="OPV72_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DedD"
                     /protein_id="HCR9915190.1"
                     /translation="MASKFQNRLVGTIVLVALGVIVLPGLLDGQKKHYQDEFAAIPLV
                     PKPGDRDEPDMMPAATQALPTQPPEGAAEEVRAGDAAAPSLDPSRMASNNVELDPIPV
                     ETPKPKPVEKPKPQPKPQQPVVAVSTPTPAPQPATDDKPAPTGKAYVVQLGALKNADK
                     VNEIVGKLRSAGFRVYTSPSTPVQGKITRILVGPDASKDKMKGSLGELKQISGLSGVV
                     MGYSPN"
     gene            complement(4527..5795)
                     /gene="folC"
                     /locus_tag="OPV72_002955"
     CDS             complement(4527..5795)
                     /gene="folC"
                     /locus_tag="OPV72_002955"
                     /EC_number="6.3.2.12"
                     /EC_number="6.3.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tetrahydrofolate
                     synthase/dihydrofolate synthase"
                     /protein_id="HCR9915191.1"
                     /translation="MKNKSIPQAASPLASWLSYLENLHSKSIDLGLERVSQVAARLDI
                     LKPAPFVFTVAGTNGKGTTCRTLESVLIAAGYRVGVYSSPHLVRYTERVRVQGKELAE
                     SAHTASFAEIEAARGDISLTYFEYGTLSALWLFKQANLDVVILEVGLGGRLDATNIVD
                     ADVAVITSIALDHTDWLGPDRESIGREKAGIFRAEKPAIVGEPEMPATIADVAQETGA
                     LLLRRGVDWRYEVTATHWAFTDGDGTLAGLPLPQVPQPNAATALAALRASGLNIDEQA
                     IRDGIAQATLPGRFQIVSESPRVIFDVAHNPHAAEYLTGRLKMLPKRGRVLAVIGMLH
                     DKDIAGTLAWLKSVVDDWYCAPLEGPRGATAEQLLEHLGKGNVYDSVAQAWQAAIDAA
                     QPEDTVLVCGSFHTVAHVMEVIDAGRIGGE"
     gene            complement(5863..6777)
                     /gene="accD"
                     /locus_tag="OPV72_002956"
     CDS             complement(5863..6777)
                     /gene="accD"
                     /locus_tag="OPV72_002956"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HCR9915192.1"
                     /translation="MSWIERIKSNITPTRKASIPEGVWTKCDSCGQVLYRAELERNLE
                     VCPKCDHHMRMSARNRLHSLLDEGSLVELGSELEPKDVLKFRDSKKYKDRLASAQKET
                     GEKDALVVMKGTLHGMPVVAAAFEFAFMGGSMGSVVGARFVRAVEQALEDNCPLVCFS
                     ASGGARMQEALMSLMQMAKTSAALAKMQERGLPYISVLTDPTMGGVSASFAMLGDLNI
                     AEPKALIGFAGPRVIEQTVREKLPPGFQRSEFLIEKGAIDMIVRRPEMRLKLASILAK
                     LMNLPAPNPDAPREGVVVPPAPDQESEA"
     gene            complement(6927..7586)
                     /locus_tag="OPV72_002957"
     CDS             complement(6927..7586)
                     /locus_tag="OPV72_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HCR9915193.1"
                     /translation="MDLIYFIIDFILHIDVHLAELVAEYGVWVYAILFLILFCETGLV
                     VTPFLPGDSLLFVAGALASLETNDLNVHVMVALMLIAAIVGDAVNYTIGRLFGEKLFS
                     NPNSKIFRRSYLDKTHQFYEKHGGKTIILARFVPIVRTFAPFVAGMGHMSYRHFAAYN
                     VIGALLWVLLFTYAGYFFGTIPLIQDNLKLLIVGIIVVSILPGVIEIVRHKRAASRAA
                     K"
     gene            complement(7635..8447)
                     /gene="truA"
                     /locus_tag="OPV72_002958"
     CDS             complement(7635..8447)
                     /gene="truA"
                     /locus_tag="OPV72_002958"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HCR9915194.1"
                     /translation="MSGQQSSPVYKIALGIEYDGSKYYGWQRQNEVRSVQEKLEKALS
                     QVANEPINVFCAGRTDAGVHGTGQVVHFETTALRKDAAWTLGVNANLPGDIAVRWVKT
                     VPDDFHARFSATARRYRYIIYNHRLRPAVLAKGVTHYYEPLDAERMHRAAQCLLGEND
                     FTSFRAVQCQSRTPWRNVMHINVTRHGPYVVVDIKANAFVHHMVRNIVGSLLEVGAHN
                     QPESWIAELLAARDRTLAAATAKAEGLYLVAVDYPDRFDLPKPPMGPLFLAD"
     gene            complement(8447..9460)
                     /locus_tag="OPV72_002959"
     CDS             complement(8447..9460)
                     /locus_tag="OPV72_002959"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HCR9915195.1"
                     /translation="MSEGWNIAILGATGAVGEALLETLAERQFPVGEIYALARHESAG
                     EHLRFGGKSVIVQDAADFDWTQAQLAFFVAGAEASAAWIDDATNAGCLVIDSSGLFAL
                     EPDVPLVVPEVNPYVLADYRNRNVIAVADSLTSQLLAALKPLIDQGGLSRIAVTSMLS
                     ASAQGKKAVDALAGQSAKLLNGIPIDEDDFFGRQLAFNMLPLLPDREGSVRQERRIVD
                     EVRKILQDDGVMISASVVQSPVFYGHAQMVSFEALRPLAAEEAREAFSRGEDIVLSEE
                     TDYPTQVGDASGNPQLSIGCVHNDYGMPEQIQFWSVADNVRFGGALMAVKIAEKLVQE
                     YLY"
     gene            complement(9528..10664)
                     /gene="pdxB"
                     /locus_tag="OPV72_002960"
     CDS             complement(9528..10664)
                     /gene="pdxB"
                     /locus_tag="OPV72_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-phosphoerythronate dehydrogenase PdxB"
                     /protein_id="HCR9915196.1"
                     /translation="MKILVDENMPYARELFSRLGEVKAVPGRPIPVEELNHADALMVR
                     SVTKVNESLLSGTPINFVGTATAGTDHVDEAWLKQAGIGFSAAPGCNAIAVVEYVFSA
                     LLMLAERDGFSLRDRTIGIVGVGNVGSRLQTRLEALGIRTLLCDPPRAARGDEGDFRT
                     LDELVQEADVLTFHTPLYKDGPYKTLHLADETLIRRLKPGAILINACRGPVVDNAALL
                     ARLNAGQPLSVVLDVWEGEPDLNVALLEAVDIGTSHIAGYTLEGKARGTTQVFEAYSA
                     FIGREQRVALETLLPAPEFGRITLHGPLDQPTLKRLAHLVYDVRRDDAPLRKVAGIPG
                     EFDKLRKNYLERREWSSLYVMCDDETAAALLCKLGFNAVHHPAH"
     gene            10768..11769
                     /gene="flk"
                     /locus_tag="OPV72_002961"
     CDS             10768..11769
                     /gene="flk"
                     /locus_tag="OPV72_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis regulator Flk"
                     /protein_id="HCR9915197.1"
                     /translation="MHPISGAPAQPPGEGRNPLSAASEQPLSMQQRTVLERLITRLIS
                     LTQQQSAEVWAGMKHDLGIKNDAPLLSRHFPAAEQNLTQRLGVAQQNHANRQVLSQLT
                     ELLGVGNNRQAVSDFIRQQYGQTALSQLTPDQLKNVLTLLQQGQLSIPQPQQRPATDR
                     PLLPAEHNTLNQLVTKLAAATGESNKLIWQSMLELSGVKSGELIPAKQFTHLATWLQA
                     RQTLSLQHAPTLHTLQAALKQPLEPDELTAIKEYAQHTYQIQPQTVLTTAQVQDLLNH
                     IFLRRVEREADELEPLSIQPIYRPFAPMIETVKNLSARPGLLFIALIIVLALFWLVS"
     gene            complement(11766..12944)
                     /locus_tag="OPV72_002962"
     CDS             complement(11766..12944)
                     /locus_tag="OPV72_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR9915198.1"
                     /translation="MTAVSQKTTTPSADFSLFRIAFAVFLTYMTVGLPLPVIPLFVHH
                     ELGYSNTMVGIAVGIQFFATVLTRGYAGRLADQYGAKRSALQGMLACGLAGAAWLLAA
                     LLPVSAPVKFALLIVGRLILGFGESQLLTGTLTWGLGLVGPTRSGKVMSWNGMAIYGA
                     LAAGAPLGLLIHSHFGFAALAGTTMVLPLLAWAFNGTVRKVPAYTGERPSLWSVVGLI
                     WKPGLGLALQGVGFAVIGTFISLYFVSNGWTMAGFTLTAFGGAFVLMRILFGWMPDRF
                     GGVKVAVVSLLVETAGLLLLWLAPTAWIALVGAALTGAGCSLIFSALGVEVVKRVPAQ
                     VRGTALGGYAAFQDISYGVTGPLAGMLATSYGYPSVFLAGAISAVVGILVTILSFRRG
                     "
     gene            complement(13124..13498)
                     /locus_tag="OPV72_002963"
     CDS             complement(13124..13498)
                     /locus_tag="OPV72_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915199.1"
                     /translation="MAKEWFTVKECLGLPGFPGSEPAVRERLYKYSEGKAGVRRKRVK
                     SKAEEFHISVFPLYVHRYLDDSGEEPTPEPISLQEAEPEDIWEMMFRLLTPEQRKQVT
                     GRFKVRGMKAVFLFLFDDTPPR"
     gene            13670..13918
                     /locus_tag="OPV72_002964"
     CDS             13670..13918
                     /locus_tag="OPV72_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCR9915200.1"
                     /translation="MEPKSQDWHRADIKSALEKRGITLRDLSRQAGLSPDSLRNVFTR
                     SWPRAERIIADALGITPQEIWPSRYGDMQIKNDADIAE"
BASE COUNT         3422 a         4120 c         3531 g         2971 t
ORIGIN      
        1 atttttataa tggcaacatg aacaatagat atgaggaatg catgtatggc atccaccaat
       61 caggaactgg cctcggcgct caggatgttt tcccgctttt tcgatttgat tcatcagccg
      121 ttggccgtca ttaatgagcg tggtgaatac gtttactaca atcaggaaag cgcggatctg
      181 gacggctaca gcattgaacg ggcaatggga aaacatatgc tggatgtcta tccgggcatg
      241 aaagaaaccc aaagtacgat gctttcatcg ttaaaaaaag gcgtggaata cattggccat
      301 tatcaaattt attacaatgc gcgaggccag gccgttgact atcagcacac caccgcgtcg
      361 ctctatgcaa gcgatggcgg catggtcggc gttatcgaaa tcggcaggaa tatgtccggc
      421 gtcaggcggc tccaggagca ggtggtagaa ctgaaccaac tgctgtatgc cgatcaccat
      481 gagaagcacc atgccattat taccgaaaat ccggaaatgc tcagtaatat cgccaaagcc
      541 aaacggctgg ccgccagtaa tattccggtg acgattgtcg gggagacggg aacgggtaag
      601 gagctatttt cccgcctgat acatcaatgc agcaagcggg cgaataagcc atttatcgcc
      661 ctgaactgcg gcgctctacc gcctacgctt atcgaaagta cgcttttcgg caccgtgcgc
      721 ggcgcctata ccggcgcgga aaatagccag ggctatctgg aactggcaaa cgggggaacg
      781 ctctttcttg atgagctgaa cgccatgccg atagaaatgc aaagtaagct gctgcgattc
      841 ttgcaggata aaaccttctg gcggctcggc ggacaacagc aactccactc tgatgtcagg
      901 atcgttgccg ccatgaacga agcgcccgtc aaattaattc aacaagaacg cctgcgggca
      961 gatctttttt atcggttgag cgtcggaatg ttgacgttac cgccgttgcg cgcccgcccg
     1021 gaagatatcc ccttactggc gaattatttt attgataaat accgtaatga cgtgccgcag
     1081 gacattcacg gattaagcga gacggcgcgt gctgatctgc tcaatcacgc ctggccgggt
     1141 aatgtcagga tgctggaaaa cgcgattgta cgcagcatga tcatgcagga aaaagacggg
     1201 ctgctgaaac acatcatttt tgaacaggac gagttaaatt taggcgtacc ggaaaccgcg
     1261 ccggagaatc cccttccctc gtcacccgat ccgcagtatg aagggtcgct ggaggtacgg
     1321 gttgccaact acgaaaggca tttaatagaa accgcgctgg atacgcatca ggggaacatt
     1381 gccgccgcgg cccgtagcct taacgtatcc cgcaccacgt tacagtacaa agtacaaaaa
     1441 tacgctattc gcttcggcgt ggtgcgtaat tgacatcggc cagcggcatc gcgccgctgg
     1501 caaagccatt agccttcgtt atgcatttcc aagttttcca tttcgttctg gaacagcacc
     1561 gctttggcgt cgtcattacg taatgaatcc aggaagtcga ggtattgctg gtctacgtct
     1621 ttggtgacat ataccccgtt aaataccgaa cattcaaact gctggatatc cgggttttct
     1681 gcgcgtacgg cttcgatcag atcgttcaga tcctggaaga taagcccgtc tgcgccgatg
     1741 atctgccgaa tctcatccac ctcgcgacca tgcgcgatca gctcattggc ggtcggcata
     1801 tcaatgccat agacgttggg gaaacgaatt tccggcgcgg cggacgccag ataaaccttc
     1861 ttcgcgccag cttcccgggc catctcgatg atctgctctg atgtggtgcc acgcacgatg
     1921 gaatcatcca ccagcaggac gttcttatcg cggaattccg cgcgattagc attgagctta
     1981 cggcgcacgg atttacggcg tagctgttgg cccggcatga taaaggtacg tcccacgtaa
     2041 cgatttttga caaatccctg gcggtacggc ttgccgagaa tacgggcaat ttccagggcg
     2101 atatcgcagg aggtttccgg gatagggatc acgacgtcga tgtccagatc ttcccattca
     2161 cgagcgattt tttcgccaag tttggtgccc atattcacac gagcgctgta gacggagatt
     2221 ttgtcgataa aggagtccgg gcgagcaaaa taaacgtact cgaacagaca ggggttactg
     2281 accggattat ccgcgcactg gcgcgtgaac agttgcccct tttcggtaat atagatagct
     2341 tcgcctggcg caacatcgcg caggaattca aagcccagcg tatccagcgc cacgctttca
     2401 gaagcgacca tatactccgt acgaccatcg ccaacgtcac gcttgcccag cactaacggg
     2461 cgaatgccgt gcggatcgcg aaaagccacc atgccgtggc cgataatcat cgctacgcag
     2521 gcataggcgc cgcggatttg acggttagtc gcggcaatcg cggcaaaaat attgtcggct
     2581 tccagcggat agtgacggaa gctgtcgagc tcgctggcga aaatattgag caggatttcg
     2641 gaatcggagg tggtgttgat atgacggcgc ttttcttcaa acagcttttt acgtagctcg
     2701 tgcgcattag tcaggttgcc attatgggcc aacgtgatgc catacggcga gttaacgtaa
     2761 aaaggttgcg cttccgaagc gctggagctg cctgcggtag ggtagcgcac atggccgatc
     2821 cccatgttgc cctgcaaacg ctgcatgtgg cgagcttcaa aaatatcgtt caccagcccg
     2881 tttgccttac gcaagcggaa gcagttattc gcatcaatgg tgatgatacc ggcagcatcc
     2941 tgaccacgat gctggagcac tgttaacgcg tcataaatcg actggttgac cggcataaca
     3001 ccggagatac cgacaatacc gcacatacgt cattttcctc gttaagccac atctcagaac
     3061 ctgttacgtc ctgggcaaga aactcgacga gctttgcaga tagtcaaaga accatctgat
     3121 gatgaagctg aactgcggga tgagctgcga tttgctccag tcttcgcttt tcgacaagcc
     3181 ggtaaaggta tcaaggaaga acagaatggc ggcgacaatc agcgcgcctc gcagtgcgcc
     3241 gaaacagatc cccaacaccc ggtcagttcc cgacaggccg gtcttttcta ctagctgacc
     3301 tatcacaaaa ttcacgatag cgccgacgat aagcgtcgcg ataaacagta ccgcgatagc
     3361 aatcccatta cgaaccagtt cgtcttcaaa gcccgtaaac cagacagaca ggtaagtgta
     3421 gtagtgactg gcgacaaaga aagcacaacc ccacgtcacc agcgataacg cttcacgaac
     3481 aaagccgcgg atcaggctaa ccagacagga aaaagcaatc accgcgataa tggcgtaatc
     3541 aatccagacc atagatgtcc cacgatttta cgccctgtcg tcctgttcgg ggcgcattct
     3601 aacagaaaaa gaaaacgttt gcgtagggat ttccttccca cgcgtaaata aaaatggcgc
     3661 tgaaaaaata ttcaacgcca tcacactttt tatctcttcg ggcacgacca gaagagctgc
     3721 catcggcctg ataagcgcag gatacccggt ttattccttc tgccggatgg cggcgtaaac
     3781 gccttatcca gcctacagaa cttcggctat taccagatga acaccgtagg ccttaacgct
     3841 gcgcgctcag gcaaaacgcg ccttagttcg ggctatatcc catcaccacg ccgcttaacc
     3901 cggaaatctg cttgagctcg ccaagcgatc ctttcatctt atctttcgac gcatccggcc
     3961 cgacgagaat acgggttatt ttaccctgta ccggcgttga gggggaagta taaacccgga
     4021 acccggcgga acgaagcttg ccgactatct cgttgacttt atccgcgttt ttcagcgcgc
     4081 ccaactgtac gacataggct ttgccggtcg gcgcaggttt atcgtcggta gccggttgcg
     4141 gcgcgggcgt cggcgtggaa acggcgacaa ccggctgttg cggtttaggc tgcggcttcg
     4201 gcttttcaac cggcttcggt ttaggcgtct ccaccggtat cggatcaagc tcgacattgt
     4261 tagacgccat gcgcgacggg tccagcgacg gcgctgccgc atctcccgcc cgcacctctt
     4321 cagccgcccc ttccggcggc tgtgtcggca gcgcctgcgt tgcggcaggc atcatatccg
     4381 gctcatcacg gtcgccaggc ttcggtacca gtggaatcgc agcaaattca tcctgataat
     4441 gctttttctg tccgtccagc agaccgggaa gcacaataac ccccagcgcg actaacacaa
     4501 tcgtgccgac taaacgattc tgaaacttac tcgccaccga ttctccccgc gtctatcact
     4561 tccataacat gtgcgacggt gtggaacgat ccgcacacca gcacggtatc ttctggctgc
     4621 gccgcgtcga tagcggcctg ccatgcctgc gcgacgctat catagacatt ccctttcccc
     4681 agatgttcca gaagttgttc cgccgtcgcg ccgcgcggcc cctctaacgg agcacaatac
     4741 cagtcgtcaa ccacgctttt caaccaggct aacgtgccgg cgatatcttt atcatgcagc
     4801 ataccaatca ccgcaagcac gcgcccgcgt ttcggcaaca ttttcagacg acccgtcagg
     4861 tattccgccg cgtggggatt atgggcgaca tcaaagataa cgcgcggcga ctcactcacg
     4921 atttgaaaac gtcccggcaa ggtagcctgc gcaataccgt cgcgaatcgc ctgttcgtca
     4981 atgttcaacc cgctggcgcg cagcgcggcc agagcggtgg cggcattcgg ctggggaacc
     5041 tgcggcaacg gcagtccggc aagcgtgccg tcgccatcgg taaacgccca gtgggtcgct
     5101 gtcacctcat aacgccagtc aacgccgcga cgcagcaaca gcgcgccggt ctcctgcgcg
     5161 acatccgcga tggttgccgg catttccggt tcgccgacga tagcgggttt ttccgcacga
     5221 aaaatcccgg ccttctcgcg gccaatactt tcgcgatccg gccccagcca gtcagtatgg
     5281 tcaagcgcga tgctggtaat taccgctaca tcggcatcca caatgttcgt ggcgtccagg
     5341 cgcccgccca acccgacctc cagaatcacc acgtcaaggt tagcctgttt aaacagccac
     5401 aatgccgaca acgtaccata ttcaaaatag gtcaatgaaa tatcgccgcg cgccgcttct
     5461 atttccgcaa aggacgcggt atgcgcggat tccgctaatt ctttcccctg cacgcgcacg
     5521 cgctcggtgt aacgtaccag atgaggtgaa ctatagacgc ccacacggta tcccgccgcg
     5581 attaacaccg actccagcgt tcgacaggtc gtacctttac cgttggttcc cgcaacggta
     5641 aaaacgaacg gcgcaggctt gaggatgtcc agacgcgctg ccacctggct tacgcgctca
     5701 aggcctaaat cgatactctt gctgtgcagg ttttccagat aagaaagcca cgaggccagg
     5761 ggcgacgcag cttgaggtat agatttgttt ttcattgatt ccgctgcttc tttacggtga
     5821 aaagcaaaag ggcagagcct gcggccctgc ccttttcagt tatcaggcct cagactcctg
     5881 atccggcgcc ggaggcacca ccacgccttc acgcggggcg tccgggttcg gcgcgggcag
     5941 attcatcagc ttcgccagaa tgctcgccag cttcaggcgc atttccggac ggcggactat
     6001 catatcaata gcgccttttt cgatcaggaa ctcactgcgc tggaatcctg gcgggagctt
     6061 ctcacgaacg gtttgttcga taacgcgcgg gccggcgaag ccaatcaggg cttttggctc
     6121 ggcgatgttg agatcgccca gcatcgcaaa actggcggaa acgccgccca ttgtcggatc
     6181 ggtcaatacc gagatgtagg gcagaccacg ttcctgcatt ttagccagcg ccgccgaggt
     6241 tttcgccatc tgcatcagcg acatcagcgc ttcttgcata cgcgcgccgc cggaagcaga
     6301 gaaacacact aacggacagt tgtcttccag cgcctgttca acggcgcgaa cgaagcgtgc
     6361 gccaacgaca gaccccattg agccacccat gaacgcgaat tcaaacgcgg cggcgacaac
     6421 cggcataccg tgaagcgtcc ctttcatgac caccagcgcg tctttctcgc cggtttcttt
     6481 ctgcgcggac gccagtctgt ctttatattt tttggagtcg cgaaacttga gcacgtcttt
     6541 cggctccagc tcgctaccca actccacaag ggaaccttca tctaacaggc tatgcaggcg
     6601 attgcgcgcc gacatgcgca tatgatggtc acacttagga cagacctcaa gattacgttc
     6661 cagctcagcg cggtataaaa cctgaccgca gctatcacac ttggtccaca ccccttcagg
     6721 aatgcttgcc ttgcgggtgg gagtaatgtt gcttttaatt cgttcaatcc agctcattgg
     6781 tgacctttct gcctgaacct tagtcagctt tattataagg ggcgcataat gccatttttg
     6841 cccccaacag accatgaatg ttgcacatta aaacataaca gcccgaaact ttggataaaa
     6901 aagtggtcga accgctgagt tactttctat tttgcggcac gcgacgcagc gcgcttatgc
     6961 cggacaatct caatgacgcc aggtaatatc gaaaccacga taatccccac aatcagcagc
     7021 ttaaggttat cctgaatcaa cggtatcgta ccgaagaaat aaccggcgta ggtaaagagc
     7081 agcacccaca gcagcgcgcc gatgacgtta taggcggcaa aatgccgata ggacatgtgc
     7141 cccatccctg ccacaaacgg cgcaaaggtt ctgacgatcg gcacgaagcg agcgagaatg
     7201 atagttttac cgccgtgttt ttcataaaac tggtgggttt tatccagata actgcggcgg
     7261 aaaattttcg aattcggatt actgaacagt ttttcgccga acagtcgacc aatcgtgtaa
     7321 tttaccgcat cgccgacaat tgcggcgatc agcattaacg ccaccatgac atgcacattg
     7381 agatcgttgg tttccagcga agccagcgcc ccggcgacaa acagcagcga gtcgcccggc
     7441 aggaacggcg tgacgaccag gccggtttca caaaacagaa tcaaaaacaa aatagcgtac
     7501 acccagacgc cgtactccgc gaccagctcc gccagatgca catcgatgtg cagaataaaa
     7561 tcaataataa agtagatcag gtccatattt gtctttgcct ttctacccga cacgtttcgg
     7621 gtgtgcgatt cggattagtc cgccagaaat agcgggccca ttggcggttt tggaaggtca
     7681 aaccggtcag ggtaatccac cgcaaccaaa tatagccctt ccgccttcgc cgttgccgcc
     7741 gccagcgttc tgtccctggc cgctaacagc tctgcgatcc agctctccgg ctggttgtga
     7801 gcgcctactt ccagcaggct gccgacaata ttcctgacca tatgatgaac aaaggcattc
     7861 gctttgatat cgaccaccac ataagggccg tggcgggtaa cgttgatgtg catcacatta
     7921 cgccacggcg tgcgcgactg gcactgcacc gcgcgaaacg aggtaaaatc attttcgcca
     7981 agcagacact gcgccgcgcg atgcatccgc tctgcatcca gcggctcata gtaatgcgtc
     8041 acgccttttg ctaataccgc aggacgcagt cgatgattgt agatgatata gcgataacgg
     8101 cgagccgtag cgctaaatcg cgcgtgaaaa tcatccggta cagttttcac ccagcgcacg
     8161 gcaatgtcac caggcaaatt cgcatttacc cccagcgtcc atgccgcatc tttgcgcaat
     8221 gcggtcgttt cgaaatggac aacctgcccg gtgccgtgaa cgccggcatc ggtgcgcccg
     8281 gcgcagaaca cgttaatagg ttcatttgcc acctgcgaga gcgctttttc cagcttttcc
     8341 tgcacgctgc gcacttcatt ctgacgctgc cagccataat acttgctgcc gtcgtactca
     8401 atacccagcg caattttata gaccggcgat gattgctgtc cggacatcag tacagatact
     8461 cctgcaccag cttctccgca attttaacgg ccatcagcgc gccgccgaaa cgcacgttgt
     8521 ccgccactga ccagaactga atttgttccg gcataccgta atcattatgc acacagccaa
     8581 tagagagctg tggattgccg gaagcgtcgc ccacctgcgt cgggtaatcc gtctcttctg
     8641 acagtacgat atcttcaccg cgggaaaacg cctcgcgcgc ctcttccgcc gccagcggac
     8701 ggagcgcttc aaagctcacc atctgcgcat ggccatagaa caccggcgac tgcacgacac
     8761 tggcggagat catcacgcca tcatcctgca aaattttacg cacttcatcg acgatacgac
     8821 gttcctggcg cacgctgcct tcccgatccg gcagcagcgg cagcatattg aacgccaact
     8881 ggcggccaaa gaaatcatct tcatcaatcg gtatgccgtt aagcagcttc gcactttgtc
     8941 cggccagcgc atcgaccgct tttttcccct gcgcggacgc tgataacata ctggtgacgg
     9001 cgatgcgcga cagtcccccc tgatcgatta acggcttgag cgccgccagc agttgactgg
     9061 tcagactatc ggcgaccgca atcacgttac ggttacggta atccgccagt acatacgggt
     9121 taacttccgg cacgaccagc ggcacatcag gctccagcgc gaacagaccg ctggaatcta
     9181 tcaccaggca acctgcattg gtcgcgtcgt ctatccaggc agccgatgcc tctgcgccgg
     9241 caacgaaaaa cgccaactgc gcctgcgtcc agtcaaagtc cgccgcatcc tggacaatga
     9301 ccgacttgcc accaaaacgg aggtgctcgc ccgcgctttc atgacgcgcc aacgcataaa
     9361 tttcaccgac cgggaactgg cgttcagcca gtgtttcaag cagggcttcg cctacggcgc
     9421 ccgttgcgcc cagaatggca atgttccagc cttcagacat ggtgatttac tccagaaata
     9481 cataagcgtc cctgtcgcat tattcgacag ggagcattaa gaagacatta atgtgccggg
     9541 tgatgaacag cgttaaaacc tagcttacac agcaaggcgg ctgccgtttc gtcgtcacac
     9601 atcacgtata aagacgacca ttcacggcgc tcaagataat ttttacgcaa tttatcaaat
     9661 tcacccggaa ttccagcgac tttacgcagt ggcgcatcgt cgcggcgcac atcatacacc
     9721 aaatgcgcca gtcttttcag cgtcggttga tccagcgggc cgtgaagcgt aatacgacca
     9781 aactcaggcg caggcagtaa tgtctccagc gcgacacgct gctcgcgacc gataaacgcg
     9841 ctatacgcct caaagacctg ggtggtgccg cgcgctttgc cttccagcgt atagccggca
     9901 atatgcgacg tgccgatatc cacggcttcc agtagcgcga cgttaagatc cggttcgccc
     9961 tcccacacat caagcaccac gctcagcggc tgcccggcat tgagtcgcgc cagcaatgcg
    10021 gcgttatcca ccaccgggcc gcggcaggcg ttaatgagaa tggcgccggg tttcagtcga
    10081 cggatcagcg tctcatcggc cagatgcagc gttttgtacg gtccgtcttt atagagcggc
    10141 gtatggaaag tcaggacatc cgcttcctgc accagctcat ccagcgtacg aaaatcaccc
    10201 tcgtccccgc gtgcggcgcg tggcggatcg cacagcaacg tgcggatacc caacgcttca
    10261 agcctggtct gtagccggct tccgacgtta cccacgccga caatccctat agtgcgatcg
    10321 cgtaacgaaa agccgtcacg ttcggccagc atcaacagcg cggaaaacac atactccacc
    10381 acggcgatag cattacagcc gggcgcggct gaaaaaccga tgcccgcctg cttcagccat
    10441 gcctcatcca catgatcggt gcctgccgta gcagtaccaa cgaagttaat cggcgtgccg
    10501 ctcagcagcg attcattcac tttcgtgacc gaacgcacca ttaacgcatc ggcatggttc
    10561 aattcttcaa cggggatcgg gcgacccggc actgccttta cctcacccag gcggctaaat
    10621 aattcgcggg cgtaaggcat attttcatca acgagaattt tcacgactgt cgtacctgtt
    10681 tgagaacgag agttaaccgg acaagtgtgc cataatctgg ccgccaagca tatattgctc
    10741 agatttatgg ttaaaggata attaattatg catcccatct ccggcgcccc tgcacagcct
    10801 ccaggcgaag ggcgtaatcc tctttccgct gcgagcgagc agccgctttc catgcaacag
    10861 cgtacggtac tggaaaggct gatcacgcgc ctgatttcac tgacccagca gcaaagcgcg
    10921 gaagtatggg ccggaatgaa acacgatctg gggataaaaa atgacgcgcc gctactgtcg
    10981 cgccacttcc ccgccgctga acagaatctt acccagcgtc tgggcgtagc gcagcaaaat
    11041 cacgccaatc gtcaggtgct ttcacagcta acagagctgc ttggcgtcgg gaataatcgt
    11101 caggccgtca gcgattttat ccgtcaacaa tacggtcaaa ccgcgcttag ccagcttacg
    11161 cccgatcaac tcaaaaacgt gctgacgctc ctgcaacagg ggcagctttc cattccgcag
    11221 ccgcaacaac gtccggcaac ggatcggcca ttattgcctg ctgaacataa tacgttgaat
    11281 cagttggtga cgaagctggc ggccgcgacc ggcgagtcaa acaaacttat ctggcaatca
    11341 atgctggaac tctccggcgt gaaaagcggc gagctcattc cggcaaaaca gtttacccat
    11401 ctggcgacat ggctacaggc gcggcagacg ctgtcactac aacacgcgcc tacgctacat
    11461 acgctgcaag ctgcgttaaa acaaccgctg gaaccggacg aactcacagc gatcaaagag
    11521 tatgcccaac acacttatca aattcagccg caaacggtgc tgaccaccgc gcaggtgcag
    11581 gatttactta accatatttt cctgcgtcgc gtagagcggg aggcggatga gctcgaaccg
    11641 ctctctattc aacccatcta ccgcccgttt gcgccgatga ttgaaaccgt gaaaaatctg
    11701 tctgcgcgac caggcctgtt gtttatcgcg ctaataattg tactggcgct tttctggctg
    11761 gtttcttaac cgcgccggaa cgataatatc gtcaccagga tgccaaccac cgcggagatc
    11821 gctcccgcga ggaatacgga aggatagccg tatgacgtgg ccagcatgcc cgccagcggg
    11881 ccggtaacgc cgtaggagat atcctgaaac gcggcgtagc cgccgagcgc cgtaccgcgt
    11941 acctgtgcag gtacgcgttt cacaacctcc acgcccagcg ccgagaaaat cagtgaacac
    12001 cctgccccgg tgagcgccgc gcctaccagc gctatccagg ccgtcggcgc cagccacaag
    12061 agcagcaacc ctgccgtctc aaccagcaat gagacaacgg cgaccttcac gccgccaaag
    12121 cgatccggca tccaaccgaa caatatgcgc atcagtacaa acgcaccgcc aaacgcggtc
    12181 agggtgaatc ccgccatcgt ccagccattg ctgacaaaat aaagtgaaat aaacgtaccg
    12241 atgacggcaa agcccacgcc ctgcaatgcc aggcccaggc ccggtttcca gataagcccg
    12301 accacgctcc acagtgaagg tcgctccccc gtatacgcag gcactttacg cacggtgccg
    12361 ttgaatgccc aggccagcag cggtaaaacc atcgtcgtcc ccgccagcgc cgcgaagcca
    12421 aagtggctat ggatcagcaa gcccaacggc gcaccggccg ccagcgcgcc gtaaatcgcc
    12481 atcccgttcc acgacatcac cttaccggaa cgcgttgggc caaccagccc cagtccccag
    12541 gtcagggttc cggtcagcag ctggctttcg ccaaatccga ggatcaaacg cccaacaata
    12601 agcagcgcga attttaccgg cgcggaaacc ggcaacagcg cggccaggag ccaggcggcg
    12661 cccgccagcc cgcaggcaag catcccctgt aacgccgatc gtttagcgcc atattgatcc
    12721 gccagccgtc cggcatagcc gcgcgtcagt accgtcgcaa aaaactgaat gcccacggcg
    12781 atcccaacca tcgtattgct atagcccagt tcgtgatgga caaaaagcgg aatgaccggt
    12841 aacggcaggc cgaccgtcat ataggtcagg aaaaccgcaa aggcgatgcg gaacagcgaa
    12901 aaatccgcag acggggtcgt tgttttttgg ctaactgctg tcatgcatta ctccagaatg
    12961 cagagtaagg cggggaaagg ccacgccccc ctctacctga acgtcaggat taaggtgcgt
    13021 tggataacgt taaacgctta cgcattatcg gaaggataat gtagaaagtg aagtctgcct
    13081 gtgagacgcg aaacttgtca accttgaaat tgcagccagg gtatcaacgc ggcggcgtgt
    13141 catcaaacag aaagagaaag accgctttca tccctctcac cttaaaccgt ccagtcacct
    13201 gcttgcgctg ttctggcgtc agtaacctga acatcatctc ccagatatct tcaggctccg
    13261 cttcctgtaa ggaaatgggt tctggcgtcg gttcctctcc gctgtcgtcc agataacgat
    13321 gaacatagag agggaaaaca gatatatgaa actcctcggc ctttgattta acacgcttac
    13381 gcctgacccc cgctttccct tcactgtact tatataaacg ttcgcgaacc gcaggctcgc
    13441 ttcccggaaa ccccggtaag ccaagacatt ccttaaccgt gaaccattcc tttgccatcg
    13501 gtttctttcc tttcccctga tgaaataaaa atatttcttc tttttcgcga aattttgctt
    13561 tctttctggc actattctta gcgtgaaaaa gaaagtaact tccttttcca tgcgctaatt
    13621 ttatcttaaa aatatcggcg ccgataacac atcttcttag gattacagaa tggaaccaaa
    13681 aagccaagac tggcatcgtg cagatattaa aagtgcactg gaaaaaagag gtattacgct
    13741 cagagatctt tctcgtcagg ccggtttatc acctgattca ctgcgcaatg tctttacccg
    13801 ttcctggccg agagccgaac ggattattgc ggacgcgctg ggcatcacgc cgcaggagat
    13861 ctggccgtcg cgctatggcg atatgcaaat aaaaaatgat gccgatatcg cagaataata
    13921 gttaatgctg aataaattgg ctttaactta tcaatctcaa caattaataa atatttaaac
    13981 ttattatatt gaaaatagta atagcacgat ctgtcatgct tcccgaatca aatactgtta
    14041 aagc
//
LOCUS       DAJVBX010000121        13915 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.121, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000121 DAJVBX010000000
VERSION     DAJVBX010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 13915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13915
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.121"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            919..2847
                     /gene="thrS"
                     /locus_tag="OPV72_002965"
     CDS             919..2847
                     /gene="thrS"
                     /locus_tag="OPV72_002965"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006894721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HCR9915201.1"
                     /translation="MPVITLPDGSQRHYDHPVSPMDVALDIGPGLAKATIAGRVNGEL
                     VDASDLIENDATLSIITAKDEEGLEIIRHSCAHLLGHAIKQLWPHTKMAIGPVVDNGF
                     YYDVDLDRTLTQEDVEALEKRMHELAEKNYDVIKKKVSWHEARETFVKRGESYKVSIL
                     DENIAHDDKPGLYHHEEYVDMCRGPHVPNMRFCHHFKLMKTAGAYWRGDSNNKMLQRI
                     YGTAWADKKALNAYLQRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRE
                     LEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNC
                     PGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGALHGLMRVRGFTQDDAHIFCTEEQ
                     IRDEVNACIRMVYDMYSTFGFEKIVVKLSTRPDKRIGSDEMWDRAEADLAVALEENNI
                     PFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPV
                     MIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVVMNITDSQSEYVNELTQKLQNAG
                     IRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVEAGKVAVRTRRGKDLGSLDVNDV
                     IEKLQQEIRSRSLQQLEE"
     gene            2851..3393
                     /gene="infC"
                     /locus_tag="OPV72_002966"
     CDS             2851..3393
                     /gene="infC"
                     /locus_tag="OPV72_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HCR9915202.1"
                     /translation="MKGGKRVQTARPNRINSEIRAQEVRLTGLEGEQLGIVSLREALE
                     KAEEAGVDLVEISPNAEPPVCRIMDYGKFLYEKSKSSKEQKKKQKVIQVKEIKFRPGT
                     DEGDYQVKLRSLIRFLEEGDKAKITLRFRGREMAHQQIGMEVLNRVKNDLQELAVVES
                     FPTKIEGRQMIMVLAPKKKQ"
     gene            3489..3686
                     /gene="rpmI"
                     /locus_tag="OPV72_002967"
     CDS             3489..3686
                     /gene="rpmI"
                     /locus_tag="OPV72_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006708231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HCR9915203.1"
                     /translation="MPKIKTVRGAAKRFKKTGKGGFKHKHANLRHILTKKATKRKRHL
                     RPKAMVSKGDLGLVIACLPYA"
     gene            3737..4093
                     /gene="rplT"
                     /locus_tag="OPV72_002968"
     CDS             3737..4093
                     /gene="rplT"
                     /locus_tag="OPV72_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HCR9915204.1"
                     /translation="MARVKRGVIARARHKKILKQAKGYYGARSRVYRVAFQAVIKAGQ
                     YAYRDRRQRKRQFRQLWIARINAAARQNGISYSKFINGLKKASVEIDRKILADIAVFD
                     KVAFTALVEKAKAALA"
     misc_feature    4209..4332
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01859"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Phe leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF01859"
     gene            4214..4258
                     /gene="pheM"
                     /locus_tag="OPV72_002969"
     CDS             4214..4258
                     /gene="pheM"
                     /locus_tag="OPV72_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pheST operon leader peptide PheM"
                     /protein_id="HCR9915205.1"
                     /translation="MNAAIFRFFFYFST"
     gene            4395..5378
                     /gene="pheS"
                     /locus_tag="OPV72_002970"
     CDS             4395..5378
                     /gene="pheS"
                     /locus_tag="OPV72_002970"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004851795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HCR9915206.1"
                     /translation="MSHLAELVANAAAAINQASDVAALDNVRVEYLGKKGHLTLQMTT
                     LRDLPPEERPAAGAVINAAKEQVQQALNARKAELESAALNARLAAETIDISLPGRRIE
                     NGGLHPVTRTIDRIESFFGELGFTVATGPEIEDDYHNFDALNIPGHHPARADHDTFWF
                     DATRLLRTQTSGVQIRTMKAQQPPIRIIAPGRVYRNDYDQTHTPMFHQMEGLIVDTNI
                     SFTNLKGTLHDFLRNFFEEDLQIRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVH
                     PNVLRNVGIDPEIYSGFAFGMGMERLTMLRYGVTDLRSFFENDLRFLKQFK"
     gene            5394..7781
                     /gene="pheT"
                     /locus_tag="OPV72_002971"
     CDS             5394..7781
                     /gene="pheT"
                     /locus_tag="OPV72_002971"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HCR9915207.1"
                     /translation="MKFSELWLREWVNPAIDSDALANQITMAGLEVDGVEPVAGSFNG
                     VVVGEVVECAQHPNADKLRVTKVNVGGERLLDIVCGAPNCRQGLKVAVATIGAILPGD
                     FKIKAAKLRGEPSEGMLCSFSELGISDDHSGIIELPADAPLGTDIREYLKLDDNTIEI
                     SVTPNRADCLGIIGVARDVAVLNKAPLQEPEMAPVTATISDTLLITVEAVDACPRYLG
                     RVVKGINVNAPTPLWMKEKLRRCGIRSIDAVVDVTNYVLLELGQPMHAFDKDRIDGGI
                     VVRMAKEGETVVLLDGSEATLNADTLVIADHHKALGIAGIFGGEHSGVNGETQNVLLE
                     CAYFNPLSITGRARRHGLHTDASHRYERGVDPALQYKTIERATRLLLDICGGDAGPII
                     DVSNEATLPKRATITLRRSKLDRLIGHHIADEQVSDILRRLGCEVTEGQDEWKAVAPT
                     WRFDMEIEEDLVEEVARVYGYNNIPDEPIQAGLIMGTHREADLSLKRVKTMLNDKGYQ
                     EVITYSFVDPKVQQLIHPGAEALLLPNPISVEMSAMRLSLWSGLLATVVYNQNRQQNR
                     VRIFETGLRFVPDTQANLGIRQDLMLAGVICGNRYDEHWNLAKETVDFYDLKGDLEAV
                     LDLTGKLGDIQFKAEMNPALHPGQSAAIYLKDERIGFIGVVHPELERKLDLNGRTLVF
                     ELEWNKLADRIVPQAREISRFPANRRDIAVVVAENVPAADILSECKKVGVNQVVGVNL
                     FDVYRGKGVAEGYKSLAISLILQDTNRTLEEEEIAATVAKCVEALKERFQASLRD"
     gene            7786..8085
                     /gene="ihfA"
                     /locus_tag="OPV72_002972"
     CDS             7786..8085
                     /gene="ihfA"
                     /locus_tag="OPV72_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integration host factor subunit alpha"
                     /protein_id="HCR9915208.1"
                     /translation="MALTKAEMSEYLFDKLGLSKRDAKELVELFFEEIRRALENGEQV
                     KLSGFGNFDLRDKNQRPGRNPKTGEDIPITARRVVTFRPGQKLKSRVENASPKEE"
     gene            8288..9268
                     /gene="btuC"
                     /locus_tag="OPV72_002973"
     CDS             8288..9268
                     /gene="btuC"
                     /locus_tag="OPV72_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin B12 ABC transporter permease BtuC"
                     /protein_id="HCR9915209.1"
                     /translation="MLTFARQQQRRNVRWLLSLSLLVLLATLLSLCAGEQWIAPGDWL
                     SARGELFVWQIRLPRTLAVLLVGAALALSGAVMQALFENPLAEPGLLGVSNGAGVGLI
                     AAVLLGQGQLPGWALGLCAIAGALIITLILLRFARRHLSTSRLLLAGVALGIICSALM
                     TWAIYFSTSFDLRQLMYWMMGGFGGVDWQQSWLMIALIPVLIWICCQSQPLNMLALGE
                     TSARQLGLPLWLWRNLLVIATGWMVGVSVAMAGAIGFIGLVIPHILRLCGLTDHRVLL
                     PGCALAGAIALLLADVVARLALASAELPIGVVTATLGAPVFIWLLLKSAR"
     gene            9360..9911
                     /locus_tag="OPV72_002974"
     CDS             9360..9911
                     /locus_tag="OPV72_002974"
                     /EC_number="1.11.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HCR9915210.1"
                     /translation="MQNSLLNTHVTTIDGEVTTLEKYAGKVLLIVNVASRCGLTPQYE
                     QLENIQKAWADQGFVVLGFPCNQFMGQEPGSEEEIKTYCASTWGVTFPMFSKIDVNGD
                     ARHPLYQKLIAAAPTAVAPEKSGFYERMVSKGRTPLYPDDILWNFEKFLVGRDGQVVQ
                     RFSPDMTPEDPIVMESIKIALAK"
     gene            9911..10660
                     /gene="btuD"
                     /locus_tag="OPV72_002975"
     CDS             9911..10660
                     /gene="btuD"
                     /locus_tag="OPV72_002975"
                     /EC_number="7.6.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin B12 ABC transporter ATP-binding protein
                     BtuD"
                     /protein_id="HCR9915211.1"
                     /translation="MSQLMQLKDVAESTRLGPLSGEVSAGEILHLVGPNGAGKSTLLA
                     RMAGLTSGEGSIRFGGAPLEAWATATLAQHRAYLAQQQNPPFAMPVWHYLTLHQPDKT
                     RTGQLNEVADMLGLGDKLGRSVNQLSGGEWQRVRLAAVVLQIHPDANPVGQLLLLDEP
                     MNSLDVAQQNALDRVLHHLCQAGIAIVMSSHDLNHTLRHAHKAWLLKRGKLIACGRRE
                     EVLTPSYLAQAYGLRFRRLDVEGHPMLISAT"
     gene            10737..11201
                     /locus_tag="OPV72_002976"
     CDS             10737..11201
                     /locus_tag="OPV72_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCR9915212.1"
                     /translation="MRFWLLVITALFLAGCSTHRAPAPNARLSDSITVIAGLNDQLQS
                     WRGTPYRYGSMSRRGVDCSGFVVVTMRDKFDLQLPRDTREQSKIGTRIDKDELLPGDL
                     VFFKTGSGESGLHVGIYDTNNEFIHASTSRGVMRSSLDNVYWRKNFWQARRI"
     gene            11515..12228
                     /gene="ydiV"
                     /locus_tag="OPV72_002977"
     CDS             11515..12228
                     /gene="ydiV"
                     /locus_tag="OPV72_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-FlhDC factor YdiV"
                     /protein_id="HCR9915213.1"
                     /translation="MIASLDELYHSELFFLPVMDENARLVGLEIIATFAAEDGAVRMP
                     TELVAPRLSVEEQYCLFVEKLALLETCQHFFIQHKLIAWLNLPPAISDLLLLDSELFS
                     RAARFPFFEVAINENYPGLNQGKNNETLANLAMHFPLILANFGAGEASTKAIFYGLFK
                     RVMLDKNFIQQRAEMISFEPFMHAIVAQISSSCESLMIAGIDTEAMFARAAPLGFSAF
                     QGGLWPPVPVSQLIKLVQR"
     gene            12290..13732
                     /locus_tag="OPV72_002978"
     CDS             12290..13732
                     /locus_tag="OPV72_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdiU family protein"
                     /protein_id="HCR9915214.1"
                     /translation="MTLSFTARWRDELPATYTALLPTPLKNARLIWYNDELAQQLAIP
                     ASLFDATNGAGVWGGETLLPGMSPVAQVYSGHQFGIWAGQLGDGRGILLGEQLLADGS
                     TLDWHLKGAGLTPYSRMGDGRAVLRSTIRESLASEAMHYLGIPTTRALSIVASDTPVQ
                     RETQETGAMLMRLAQSHMRFGHFEHFYYRREPEKVQQLADFAIRHYWPQWQDVAEKYA
                     LWFEEVAARTGRLIAEWQTVGFSHGVMNTDNMSILGLTIDYGPFGFLDDYDPGFIGNH
                     SDHQGRYRFDNQPSVALWNLQRLAQTLTPFIEIDALNRALDRYQDALLTHYGQRMRQK
                     LGFFTEQKDDNALLNELFSLMAREGSDYTRTFRMLSHTEQQSASSPLRDTFIDRAAFD
                     AWFDRYRARLRTEAVDDALRQQQMQRVNPAIVLRNWLAQRAIDAAEQGDMAELHRLHE
                     VLRQPFTDRDDDYASRPPEWGKRLEVSCSS"
     gene            complement(13768..>13915)
                     /gene="hemP"
                     /locus_tag="OPV72_002979"
     CDS             complement(13768..>13915)
                     /gene="hemP"
                     /locus_tag="OPV72_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hemin uptake protein HemP"
                     /protein_id="HCR9915215.1"
                     /translation="DNETLLPAAERRVNSQALLGPDGKVIIDHNGQEYLLRKTQAGKL
                     LLTK"
BASE COUNT         3425 a         3269 c         3773 g         3448 t
ORIGIN      
        1 taatgcaatg tatgaaatta taagcatata gagcctttag aaaaaatgct tagtattaaa
       61 aatattacca tcaggcaaat aaggtgtggt acggaaaatc ttctggcaag atattctgaa
      121 tctggtagtc tataatcatt actcatcact atcttcccga tatcaaaacc gtgttattga
      181 aatattaaca ctcattaaca ctcctatcta ctgcgcctcc gatagcatga agctatcaag
      241 cgtttgcagc acaaacatca aacaatgtaa atgcttttga taattacgca tgattgttac
      301 tgtgtttata tacagtggca ttcgaagatt catcatgagg ttcccgagtc ctgtaaaaga
      361 ctatacagag aaagagctat cactcgacga gtaattcatc tcacatcgtg ccgcgacata
      421 cttcaagcaa cacagacgaa ttacaagtac ggcatcataa gtgagacgtt gctagttata
      481 gaagcttcat agcagcatgt aatggctctt tgctggtatg tgctttggaa agtgggtttc
      541 gtattgtgcg ttatcgcatg ctgccaggtc cccatctgga gaatatagat agcggtcgtc
      601 gtgaaaagct atctgatgtg aatgcctcat acggtggcag taagccgaga ttcagagtga
      661 ccatgtacat cattaacgat acgcgtgccg ggtagtgtgt tgggattcag gttctgtaga
      721 acagaaagat gcaatctccc tttttttagt gttaccatca tcatgccgga cgaaaatagc
      781 gattttcgtc tgtgtcgaag gttgtgcgcc aatttagcaa tggttggcta gatggataca
      841 caactcactg tcaataaatt cattttctct ttgtatgtga tcttgcgtat gggtcaccac
      901 tgcaaataag gatattacat gcctgttatt actcttcctg atggcagcca acgccattat
      961 gaccaccctg taagcccgat ggatgttgct ctggacattg gtcctggcct ggcgaaagcc
     1021 accattgcgg gccgtgtgaa tggcgagctg gttgatgctt ccgatctgat tgaaaatgat
     1081 gcgacgcttt ccatcatcac cgcaaaagat gaagagggtc tggagatcat tcgtcactct
     1141 tgcgcgcatc tgttaggtca cgctatcaag caactttggc cgcacacgaa aatggcgatc
     1201 ggtccggttg tcgacaacgg tttttactat gacgttgatc ttgaccgcac gctaactcag
     1261 gaagatgtcg aagcgctcga aaagcggatg catgagctcg ccgagaaaaa ttacgacgtt
     1321 atcaagaaga aagtcagctg gcacgaagcg cgtgaaacct tcgtgaagcg tggtgaaagc
     1381 tacaaagttt ccattcttga tgaaaacatt gctcatgatg acaagccagg cttgtaccat
     1441 catgaagaat atgtcgacat gtgtcgtggt ccgcacgtgc cgaatatgcg tttctgccat
     1501 cactttaaac tgatgaaaac tgccggcgca tactggcgcg gtgacagcaa taataagatg
     1561 ttgcagcgta tttacggtac ggcatgggca gataaaaaag ccctgaacgc ttatctgcag
     1621 cgcctggaag aggccgcaaa acgcgaccac cgtaaaattg gtaagcagct cgacctgtat
     1681 catatgcagg aagaagcgcc gggcatggtg ttctggcata acgacggctg gactatcttc
     1741 cgcgagctgg aggtctttgt tcgttctaaa ctcaaagagt accagtatca agaagttaaa
     1801 ggcccgttca tgatggaccg tgtgctgtgg gaaaaaaccg ggcactggga caactataaa
     1861 gatgcgatgt tcaccacatc ttcagaaaac cgcgaatatt gcatcaagcc gatgaactgc
     1921 ccgggccacg ttcagatctt taaccagggt ctgaaatcct atcgtgattt gccgctgcgt
     1981 atggcggaat tcggtagctg ccaccgtaac gagccatcag gcgcgctgca tggtctgatg
     2041 cgcgtacgcg gctttacgca ggatgatgcg catatcttct gcaccgaaga gcagatccgc
     2101 gatgaagtta acgcttgtat tcgtatggtc tacgatatgt acagcacctt tggcttcgag
     2161 aagatcgtcg tcaaactttc cactcgtcct gataagcgta tcggcagcga tgagatgtgg
     2221 gatcgtgctg aggcggatct ggcggttgcg ctggaagaaa ataatatccc gtttgagtat
     2281 caactgggtg aaggcgcatt ctacggtccg aaaattgaat ttaccttata tgactgcctc
     2341 gatcgtgcat ggcagtgcgg tacagtacag ctggacttct ccttaccgtc tcgtctgagc
     2401 gcctcctatg taggcgaaga caacgagcgc aaggtgccgg taatgattca ccgtgcgatt
     2461 cttgggtcga tggaacgctt catcggtatc ctgaccgaag agttcgctgg tttcttcccg
     2521 acatggctcg cgcctgttca ggtagtcgtg atgaatatta ccgattcgca gtctgaatac
     2581 gttaacgaat tgacgcagaa actacaaaat gcgggcattc gtgtaaaagc agacttgaga
     2641 aatgagaaga ttggctttaa aatccgcgag cacactttac gtcgtgtccc ttatatgttg
     2701 gtctgtggtg ataaagaggt ggaagcaggc aaagttgccg ttcgcacccg ccgcggtaaa
     2761 gacctgggca gtctggacgt aaatgacgtg attgagaagc tgcaacaaga gattcgcagc
     2821 cgcagtcttc aacaactgga ggaataaagt attaaaggcg gaaaacgagt tcaaacggcg
     2881 cgtccgaatc gtattaatag cgaaattcgc gcgcaagaag ttcgcttaac aggtctggaa
     2941 ggcgagcagc ttggtattgt gagtctgaga gaagctctgg aaaaagctga agaagccgga
     3001 gtagacttag tcgaaatcag ccctaacgcc gagccgccgg tttgtcgtat aatggattac
     3061 ggcaaattcc tctatgaaaa gagtaagtct tctaaggaac agaagaaaaa gcaaaaagtt
     3121 atccaggtga aggaaattaa attccgtcct gggacagatg aaggcgacta tcaggtaaaa
     3181 ctccgcagcc tgattcgctt tctcgaagag ggcgataagg ccaagatcac gctgcgtttc
     3241 cgcggtcgtg aaatggccca ccagcaaatc ggtatggaag tgcttaatcg cgtgaaaaac
     3301 gatttgcaag aactggcagt ggtcgaatcc ttcccaacga agatcgaagg ccgtcagatg
     3361 atcatggtgc ttgctcctaa gaagaaacag taaggccttc aagtaacaat tctgtgaagc
     3421 cttcgggctt cacaggtttt gttcgcctat gtttcgttta ttaacaatgc gaagtggaag
     3481 ttattaaaat gccaaaaatt aagaccgtac gcggtgctgc taagcgcttc aaaaaaaccg
     3541 gtaaaggtgg ttttaagcac aagcacgcta acctgcgtca cattctgacc aaaaaagcga
     3601 ctaaacgtaa acgtcacctg cgtccgaaag ccatggtttc taaaggcgat ctgggcttgg
     3661 ttatcgcgtg cctgccgtac gcataagccg ttaacgtttt taacttttta attagaatag
     3721 atacaggaga gcacatatgg ctcgcgtaaa acgtggtgta attgcacgcg cacgtcacaa
     3781 gaaaattttg aaacaagcca aaggctacta cggtgcgcgt tctcgcgtat accgcgttgc
     3841 cttccaggca gttatcaaag ctggtcagta tgcttaccgt gaccgtcgtc aacgtaagcg
     3901 tcagttccgt caactgtgga ttgcgcgtat caacgcagca gcacgtcaga acggtatttc
     3961 ttacagcaaa ttcatcaacg gcctgaaaaa agcctctgtt gaaatcgacc gtaagatcct
     4021 ggctgatatc gccgtattcg acaaagtcgc gttcaccgcg ctggttgaaa aagcgaaagc
     4081 agctctggca taagccagtg aaaagaggga gcctggctcc ctctctttta tttactgttc
     4141 agtgagttga caattgacct gtaacccttt tcaataaagg atattcggtt ttaccacata
     4201 aggtaacgca agcatgaacg ctgctatttt ccgtttcttt ttttacttta gcacctgatc
     4261 ccaggaggct agcgcgtgaa aaacgaaacg aaaaacagcg taaaaaagcc tcctgatgga
     4321 ggcttttttt gtatctgaaa tcgagagatt acgtccaatg aaccggtgtc ttcaccgaca
     4381 caatgaggaa aaccatgtca catctcgcag agctggttgc caatgcagcg gccgccatta
     4441 accaggcgtc agatgttgcc gcgttagaca atgtacgcgt cgaatatttg ggcaagaaag
     4501 ggcatttaac ccttcagatg acgaccctac gcgatctgcc gccggaagag cgtccggcag
     4561 ccggggcagt cattaacgcc gcgaaagagc aggtacaaca ggcgcttaac gcgcgtaaag
     4621 ccgagctgga aagcgcagcg cttaacgctc gtctggccgc tgaaactatc gatatctccc
     4681 tgccgggacg ccgtattgag aacggcggtc tgcatccggt cacgcgtacc attgaccgta
     4741 ttgaaagttt cttcggcgag cttggtttta ccgtggcgac tggcccggaa atcgaagatg
     4801 actaccataa cttcgatgcg ttaaacattc cgggtcatca cccggcccgc gccgatcatg
     4861 ataccttctg gtttgacgcg acccgtctgc tgcggaccca gacgtctggt gtccagatcc
     4921 ggacgatgaa agcgcagcaa ccgccgatcc gtattattgc gccgggccgt gtataccgta
     4981 atgactacga ccagacgcat actccgatgt tccatcagat ggaaggtctg attgttgata
     5041 ccaacatcag cttcaccaac ctcaaaggta cgctgcacga cttcctgcgt aatttctttg
     5101 aggaggatct gcagattcgc ttccgtcctt cttattttcc gttcaccgaa ccttctgcgg
     5161 aagtggatgt gatgggtaaa aacggcaaat ggctggaagt gctgggctgc gggatggtgc
     5221 atccgaatgt gctgcgtaat gtcggtatcg atccggaaat ctattctggc ttcgcttttg
     5281 gtatggggat ggaacgtctg accatgttgc gttacggcgt caccgacctg cgttcattct
     5341 tcgaaaacga tctgcgtttc cttaaacagt ttaaataaag gcaggataaa acaatgaaat
     5401 tcagcgaact gtggttacgc gagtgggtta acccggcaat tgatagcgat gcgttggcta
     5461 accagattac gatggctggc ctggaagtag acggcgttga gccggtcgcg ggaagcttca
     5521 atggcgttgt ggttggggaa gtggttgagt gcgcccagca tccgaacgct gacaaattgc
     5581 gtgtaacgaa agtcaacgtc ggcggagaac gcctgttgga tatcgtctgc ggcgcgccaa
     5641 actgtcgtca ggggctgaaa gtagcggtgg ccactattgg cgctattctg ccgggcgatt
     5701 tcaaaattaa agcggcgaaa ctgcgcggcg aaccgtctga agggatgctg tgctccttct
     5761 ccgaactggg gatttccgac gatcacagcg gcattatcga actgccggcg gatgcgccgt
     5821 tgggtaccga catccgtgaa tacctgaagc ttgacgacaa taccatcgaa attagcgtca
     5881 cgccgaaccg tgcggattgc ttaggtatca tcggcgttgc gcgtgatgtg gcggtactga
     5941 acaaagcgcc gctccaggag cctgaaatgg cgccggttac ggcaaccatc agcgatacgc
     6001 tgctgattac ggtagaggct gttgatgcgt gtcctcgcta tcttggccgg gtggtaaaag
     6061 gtatcaatgt taacgcgccg acgccgctgt ggatgaaaga gaaactgcgt cgctgcggta
     6121 ttcgctccat cgatgcggtg gttgacgtca cgaactatgt gctgctcgaa ctgggtcagc
     6181 caatgcatgc tttcgataaa gatcgcattg atggcggtat tgtcgtgcgg atggcaaaag
     6241 agggtgaaac cgtcgtcctg ctggacggta gcgaagcgac gttaaatgcg gacacgctgg
     6301 tgatcgccga tcaccataag gcgctgggga tagccggtat ttttggcggc gaacattccg
     6361 gcgtgaacgg cgaaacgcaa aatgtgctgc tggagtgtgc gtactttaat ccgctgtcta
     6421 tcaccggtcg cgctcgccgc cacggtctgc ataccgatgc gtctcaccgc tacgagcgcg
     6481 gggtggaccc ggcgctgcaa tataaaacga tagagcgcgc tactcgtctg cttcttgata
     6541 tctgtggcgg tgatgcgggt ccgataattg atgtgagcaa cgaagcaacg ttgccgaaac
     6601 gcgccaccat tactctgcgt cgcagtaaac tggatcgcct gatcgggcat catattgcgg
     6661 atgagcaggt cagtgatatt ctgcgtcgtc tgggctgtga agtgaccgaa gggcaggacg
     6721 agtggaaagc cgtggcgccg acctggcgtt tcgatatgga gattgaagaa gatctggtgg
     6781 aagaggtggc ccgcgtttac ggctataaca atattccgga cgagccaatc caggccggtt
     6841 taatcatggg aacgcaccgt gaagccgatc tgtcgttgaa gcgggttaaa accatgctga
     6901 acgacaaagg ctatcaggaa gtgattacct atagctttgt cgatcctaaa gtacaacagc
     6961 tcatccatcc aggcgcagaa gcgctgctgc tgccaaaccc tatctccgtt gagatgtcgg
     7021 cgatgcgtct gtctctgtgg agcggattgt tggcgacggt ggtctataac caaaaccgtc
     7081 agcagaatcg cgtgcgtatt tttgaaaccg gtttacgttt cgttccggat acacaagcca
     7141 atctgggtat tcgacaggat ctgatgctgg ctggcgtgat ttgcggtaac cgctatgatg
     7201 agcactggaa cctggcaaaa gagaccgttg atttctatga tttgaaaggc gatctggaag
     7261 cagtattgga tttaaccggc aaactgggtg atatccagtt taaggcggag atgaatccgg
     7321 ctctgcatcc gggacagtct gcggcgattt atctgaaaga tgaacgtatt ggttttattg
     7381 gggttgttca ccctgaactg gaacgtaaac tggatctgaa tggtcgtacg ctggtgtttg
     7441 aactggaatg gaataagctc gcagaccgta tcgtgccgca ggcgcgggag atttcacgct
     7501 tcccggccaa ccgtcgcgat attgcggttg ttgttgcaga aaacgttccc gcagcggata
     7561 ttttatccga atgtaagaaa gttggcgtaa atcaggtagt tggcgtaaac ttatttgacg
     7621 tgtaccgcgg taagggtgtt gcggagggtt ataaaagcct cgctatcagc ctgatccttc
     7681 aggataccaa ccgtacactc gaagaagagg agattgccgc taccgtcgcc aaatgtgtag
     7741 aggcattaaa agagcgattc caggcatcat tgagggattg aacctatggc gcttacaaaa
     7801 gctgaaatgt cagaatatct gtttgataag cttgggctta gcaagcggga tgccaaagaa
     7861 ctggttgaac tgtttttcga agagatccgt cgtgctctgg aaaacggtga gcaggtgaaa
     7921 ctctctggtt ttggtaactt cgatctgcgt gataaaaatc aacgtccggg gcgtaacccg
     7981 aaaacgggtg aagatattcc tattacagca cggcgcgtgg tgaccttcag acccgggcag
     8041 aagttaaaga gccgggtcga aaacgcttcg cccaaagaag agtaatcaga tccaggcata
     8101 acatccatca gggtgtattg cggcagatac gctgccatcc cgaaagtaga tcagcgggat
     8161 gacagcgtat ttgtcagcct gaaagatgac ccgtataact aaaaaggccg cattgcggcc
     8221 ttttttcttt caagtaaagg atacccaccg taaaatcacg ctacctcttt tcagctgaat
     8281 ggataacatg ctgacttttg cccgccaaca acagcgacga aacgttcgct ggcttctgag
     8341 cctgtcactg ctggtgctac tggctacact tctgagctta tgcgcaggcg aacagtggat
     8401 tgcccccggt gactggttaa gcgcccgggg ggaactgttt gtctggcaaa ttcgccttcc
     8461 ccgcacgctt gcggtattgc tggttggcgc tgcgctggcg ctatctggcg ccgtgatgca
     8521 ggcgctgttt gaaaacccac ttgctgaacc gggtctgctc ggcgtttcga atggggccgg
     8581 tgttgggctt attgccgccg tcttactggg gcaggggcaa ctgccaggat gggcgctggg
     8641 gctgtgcgct atagccggcg cgctcattat tacgttaatc ctgctgcgtt ttgcgcgtcg
     8701 ccatctctct accagccgct tgttgttggc gggcgtcgcg ctgggcatta tctgtagcgc
     8761 gctgatgacg tgggctatct atttttccac ctctttcgat ctgcggcaat taatgtactg
     8821 gatgatggga ggatttggcg gcgttgactg gcagcagagc tggctaatga ttgcgctcat
     8881 cccggtactg atctggatat gttgccagtc gcaaccgctg aatatgctgg cgctagggga
     8941 aacctcggcg cggcagcttg gcctgccgct gtggctctgg cgcaatttgt tggtcatcgc
     9001 caccggctgg atggtgggcg tcagcgtggc gatggcgggg gcgattggtt ttatcggtct
     9061 ggttattccg cacatcctgc gcttatgtgg tttaaccgat caccgggttt tacttcccgg
     9121 ctgcgcgctg gccggggcta tcgccctgct attggctgat gtggtcgccc gactggcgct
     9181 ggcgtcggct gaactgccta tcggggtggt caccgccaca ttgggggcac cagtgtttat
     9241 ctggctgcta ctcaaatccg cgcgttagcg catcggtaaa caactgcttt catcattcgc
     9301 agtctatgat taaaggctaa cgatgaaacc cgctattcta ccgacatcag ggagacacca
     9361 tgcaaaactc gcttcttaat actcacgtta cgacgattga tggagaggtc actacacttg
     9421 aaaaatacgc cggaaaagtg ctgctcattg taaacgtcgc ctccagatgt ggcctgacgc
     9481 cgcaatatga acagttggaa aatatccaga aggcgtgggc agatcagggg tttgtcgtgt
     9541 tgggttttcc ctgcaaccag tttatggggc aggagccagg cagcgaagag gagattaaaa
     9601 cctattgtgc cagcacctgg ggcgtcacgt tcccgatgtt cagtaaaatt gatgtgaatg
     9661 gcgacgcgcg ccatccgctg tatcaaaaac tgatagccgc tgcgccaacg gcagtcgcgc
     9721 cggagaagag cggcttttac gaacggatgg taagcaaagg gcgtacgcca ctctatccgg
     9781 atgatattct gtggaatttt gaaaaatttt tggtaggccg ggatggtcag gtggtacagc
     9841 gtttttcgcc ggatatgacg cctgaagatc ctattgtgat ggaaagcata aaaatcgcgt
     9901 tggcaaaata atgtctcaat tgatgcaatt aaaggacgtc gccgagagca cccgcctggg
     9961 gccgctttcc ggcgaagtaa gcgcaggaga gatccttcat cttgtcgggc cgaacggcgc
    10021 cgggaaaagc acgctactgg cgcgtatggc ggggttaacc tccggcgagg ggagcatcag
    10081 gtttggcgga gcgccgctgg aggcatgggc gacggcaacg cttgcccaac accgcgctta
    10141 tcttgcgcaa cagcaaaatc cgccgttcgc catgccggtc tggcattacc tgacattgca
    10201 tcaacctgat aaaacgcgaa ccgggcagct taacgaggtg gccgatatgc ttggattggg
    10261 cgacaaactg gggcgaagcg tgaatcagct ttccggtggc gagtggcagc gcgttcgcct
    10321 tgctgccgtt gtactacaaa ttcatcccga cgctaatccg gtcggtcaat tattgctgct
    10381 tgatgagccg atgaacagtc tcgatgttgc gcaacaaaac gctctggatc gggtattaca
    10441 tcatttatgt caggcaggaa ttgcgattgt gatgagtagc cacgatctga accacacgct
    10501 gcgccatgcg cataaagcct ggttactaaa gcgcggtaaa ctcattgcct gcggccgccg
    10561 ggaagaggtg ctcaccccct cttatctggc gcaagcctac ggtttgcgct ttcgacgact
    10621 cgacgtcgag gggcatccaa tgctcatttc ggccacttaa gtaaaatcgt ttcttgaaaa
    10681 gcaggtaatt tcgacgctaa attaatacca aaataaaaac agaggattgt tgcggcatgc
    10741 gtttttggct tcttgttatc acagcattgt tcctggcagg atgcagtact catcgggcac
    10801 cggcgccaaa tgccagatta tcagactcca ttaccgtcat tgcgggtctg aacgatcagt
    10861 tgcagtcctg gcgcggtacg ccataccgct acggcagcat gagtcgcaga ggcgtggact
    10921 gttccggctt tgtggtagtc actatgcgcg acaagtttga tttgcagttg cctcgtgata
    10981 cgcgtgaaca atcaaaaatc ggcaccagaa tcgataaaga tgaattgctg cccggagatt
    11041 tggttttctt taaaaccggt tcgggcgaaa gtggtttaca tgttggtatt tacgatacaa
    11101 ataatgagtt tattcatgcc tctaccagtc gtggcgtgat gcgttcatcg ctggataatg
    11161 tgtactggcg aaaaaacttc tggcaggcac ggcgaattta acctcgcaga cgatataaat
    11221 tttatagtct atttttaaca tatcgccagt tgaacttatg acatctgttg tcatcatata
    11281 taatgatata accgtagcat ttacaaacgt acttttatta aaaacgggcg tgctcacgcc
    11341 ctgttaaaag tacaacattg gatattggtt tataatcaga gtaagttaaa aaaaggaacc
    11401 ggttcaccgg taaacaagaa aaatgatgac gcttcaatta gtatctgaag ttacgtctgt
    11461 ttccgtccgt agtgactgga tggtgaatag cgccctaacc atgggactgg cgtaatgatt
    11521 gcttcacttg atgagcttta ccattccgaa ctctttttcc ttcccgtcat ggatgaaaac
    11581 gctcggcttg ttggtttaga gattattgca acgtttgccg ctgaagacgg cgccgtgcgg
    11641 atgccgactg agttggtagc gcctcgcctt tcggtggagg aacaatactg tctgtttgtt
    11701 gaaaaactgg cgttgttaga aacctgtcag cactttttta ttcagcataa acttattgca
    11761 tggcttaatt taccgcctgc aattagtgac ttattattat tagatagcga acttttttcc
    11821 cgggcagcgc gctttccgtt ttttgaagta gctataaatg agaattatcc tgggttaaac
    11881 cagggcaaaa acaatgaaac gttagctaat ctggcaatgc atttcccatt aattttggca
    11941 aattttgggg caggcgaggc gtcgactaaa gctattttct atgggctttt caaacgagtc
    12001 atgttggata aaaattttat tcagcagcga gctgaaatga tctcattcga accattcatg
    12061 cacgctattg ttgcccagat ctcctccagc tgcgagtcgc tgatgattgc cggtattgat
    12121 actgaggcga tgtttgcgcg cgcagcgcca ttggggttta gcgcattcca gggcggacta
    12181 tggcctccgg tgccggtaag ccagctcatt aaactcgttc agcgataacc tttctgtttg
    12241 ccggtgttta accggtgatt aaccgtctac actgaagaca ggaggcccta tgaccctgtc
    12301 ttttactgcc cgttggcgcg atgaattgcc agcaacgtat accgcgcttt tacccacacc
    12361 gttaaaaaat gcgcgactga tttggtataa cgacgaactg gcgcagcagt tagccattcc
    12421 cgcttcgtta tttgacgcta ccaatggcgc tggcgtttgg ggcggcgaaa ccttattacc
    12481 cggtatgtcg cctgtcgcgc aggtatatag cgggcatcag ttcggcatct gggcgggaca
    12541 actcggcgac ggacgcggta ttttgctggg cgaacagctc ctggcggatg gctcgaccct
    12601 cgactggcat ctgaaaggcg ccggattaac accctattcg cgaatgggag atggacgcgc
    12661 cgtcctgcgt tcaaccatac gagaaagtct tgccagcgaa gctatgcatt atctgggtat
    12721 tcccactacg cgcgcgttat ctatcgtagc cagcgatacg ccggttcagc gagagacgca
    12781 ggaaacgggc gcgatgttaa tgcgtctggc acaaagtcat atgcgttttg gtcatttcga
    12841 acatttctat taccgccgtg agccggaaaa agttcagcaa ctggctgatt tcgctattcg
    12901 tcattactgg ccgcaatggc aggatgtagc ggaaaaatat gctttgtggt ttgaagaggt
    12961 ggcggcgcgt accggaagac tcatcgccga gtggcaaacc gtcggttttt cgcacggcgt
    13021 tatgaatacg gataacatgt cgattctggg gctgaccatc gactatggcc cctttggttt
    13081 tctcgacgac tacgatcccg gcttcattgg taaccattcc gatcatcagg gacgttaccg
    13141 cttcgataat caaccgtcgg tggcgctgtg gaatttacaa cgtctggcgc agacgttaac
    13201 cccttttatt gagatcgacg cgttaaacag agcgctggat cgttaccagg acgcgttgtt
    13261 aacgcactat gggcagcgaa tgcgccagaa gctgggcttc tttaccgagc aaaaagacga
    13321 taacgcttta ctgaatgaat tgtttagtct gatggcgcgc gaagggagtg attatacccg
    13381 tacatttcgg atgttaagcc atacggagca acagagcgcc tcctcgccgt tgcgggatac
    13441 gtttatcgat cgcgcggcgt tcgatgcctg gttcgaccgc taccgggcgc gattgcgcac
    13501 agaggcggtg gatgacgcgc tgcgccaaca gcagatgcaa cgcgtgaatc ctgcgattgt
    13561 gttgcgcaac tggctggcgc aacgcgcgat agatgcggct gaacaaggag acatggcgga
    13621 actgcatcgg ttgcatgaag ttttacgtca accttttacc gatcgagatg atgactatgc
    13681 cagccgaccg ccggagtggg gaaagcggct ggaggtcagt tgttcaagtt agccagatgc
    13741 cagcagaatc gtctgctggc gggagcgcta tttggttaac agtagcttac cggcctgagt
    13801 tttgcgcaac agatactcct gaccgttgtg atcgataatg actttgccgt ccggacctaa
    13861 tagcgcctga ctgttgacgc gccgttcagc ggcagggaga agcgtttcat tgtct
//
LOCUS       DAJVBX010000122        13790 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.122, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000122 DAJVBX010000000
VERSION     DAJVBX010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 13790)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13790)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13790
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.122"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(255..932)
                     /gene="narI"
                     /locus_tag="OPV72_002980"
     CDS             complement(255..932)
                     /gene="narI"
                     /locus_tag="OPV72_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="respiratory nitrate reductase subunit gamma"
                     /protein_id="HCR9915216.1"
                     /translation="MHFLNMFFFDIYPYIAGSVFLIGSWLRYDYGQYTWRAASSQMLD
                     RKGMNLASNLFHIGILGIFAGHFLGMLTPHWMYEAFLPVDVKQKMAMIAGGACGMLTL
                     VGGILLLKRRLFSPRVRATTTGADILILSLLVIQCALGLLTIPFSAQHMDGSEMMKLV
                     GWAQSVVTFHGGASAHLDGVAFIFRMHLVLGMTLFLLFPFSRLVHIWSVPVEYLTRKY
                     QIVRARH"
     gene            complement(932..1642)
                     /gene="narJ"
                     /locus_tag="OPV72_002981"
     CDS             complement(932..1642)
                     /gene="narJ"
                     /locus_tag="OPV72_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase molybdenum cofactor assembly
                     chaperone"
                     /protein_id="HCR9915217.1"
                     /translation="MIELVIVSRLLEYPDAALWQHQQELFDALASSENLDKEDAQTLG
                     VFLRDLTAQDMLDVQAAYSELFDRGRATSLLLFEHVHGESRDRGQAMVDLMAQYEQHG
                     LQLDSRELPDHLPLYLEYLAQLPKSEALGGVQDIAPILALLSARLQQRDSRYAVLFDL
                     LLKLANTVIDSGKVAEKIANEARDDTPQALDAVWEEEQVKFFADQGCGESEISAHQRR
                     FAGAVAPQYLNITTGGQH"
     gene            complement(1639..3174)
                     /gene="narH"
                     /locus_tag="OPV72_002982"
     CDS             complement(1639..3174)
                     /gene="narH"
                     /locus_tag="OPV72_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit beta"
                     /protein_id="HCR9915218.1"
                     /translation="MKIRSQVGMVLNLDKCIGCHTCSVTCKNVWTSREGMEYAWFNNV
                     ESKPGVGFPNDWENQEKWKGGWIRKINGKLQPRMGNRALLLGKIFANPHLPGIDDYYE
                     PFDYDYQNLHTAPESKHQPIARPRSLITGQRMDKITSGPNWEEILGGEFEKRAKDQNF
                     ENMQKAMYGQFENTFMMYLPRLCEHCLNPACVATCPSGAIYKREEDGIVLIDQDKCRG
                     WRMCITGCPYKKIYFNWKSGKSEKCIFCYPRIEAGQPTVCSETCVGRIRYLGVLLYDA
                     DAIESAASTENEKDLYQRQLDVFLDPNDPAVIEQALKDGVPQSVIDAAQQSPVYKMAM
                     DWKLALPLHPEYRTLPMVWYVPPLSPIQSAADAGELGSNGILPDVDSLRIPVQYLANL
                     LTAGDTQPVLLALKRMLAMRHYKRAETVDGKVDTRALEEVGLSEAQAQEMYRYLAIAN
                     YEDRFVVPSSHRELARDAFPEKSGCGFTFGDGCHGSDTKFNLFNSRRIDAVDVTSKTE
                     PHA"
     gene            complement(3171..6914)
                     /locus_tag="OPV72_002983"
     CDS             complement(3171..6914)
                     /locus_tag="OPV72_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit alpha"
                     /protein_id="HCR9915219.1"
                     /translation="MSKFLDRFRYFKQKGETFADGHGQLLETNRDWEDGYRQRWQHDK
                     IVRSTHGVNCTGSCSWKIYVKNGLVTWETQQTDYPRTRPDMPNHEPRGCPRGASYSWY
                     LYSANRLKYPLMRKRLMKMWREAKKLHRDPVEAWASIIEDADKAKSFKQARGRGGFVR
                     SSWQEVNELIAASNVYTVKTYGPDRVAGFSPIPAMSMVSYASGARYLSLIGGTCLSFY
                     DWYCDLPPASPQTWGEQTDVPESADWYNSSYIIAWGSNVPQTRTPDAHFFTEVRYKGT
                     KTVAVTPDYAEIAKLCDLWLAPKQGTDAAMALAMGHVMLREFHLDNPRQYFTDYVRRY
                     TDMPMLVMLEERDGYYAAGRMLRAADLVDSLGQENNPEWKTVAINSNGEMVAPNGSIG
                     FRWGEKGKWNLEQRDGTTGAETELQLSLLGSQDEIADVGFPYFGGEGSEYFNHVALDN
                     VLLHKLPAKRLQLADGSSALVTTVYDLTMANYGLERGLNDENCAASYDDTKAYTPAWA
                     EQITGVPRAQIIRIAREFADNADKTHGRSMIIVGAGLNHWYHLDMNYRGLINMLVFCG
                     CVGQSGGGWAHYVGQEKLRPQTGWQPLAFALDWQRPARHMNSTSYFYNHSSQWRYETV
                     TAEELLSPMADKSRYSGHLIDFNVRAERMGWLPSAPQLGTNPLYIAREAEKAGMTPVD
                     YTVKSLKDGSIRFAAEQPENGKNHPRNLFIWRSNLLGSSGKGHEYMLKYLLGTEHGIQ
                     GLDLGKQGGVKPEEVEWRDNGLDGKLDLVVTLDFRLSSTCLCSDIVLPTATWYEKDDM
                     NTSDMHPFIHPLSAAVDPAWESKSDWEIYKGIAKKFSEVCVGHLGKETDVVTLPIQHD
                     SAAELAQPLDVKDWKKGECDLIPGKTAPHIMTVERDYPATYERFTSIGPLMEKIGNGG
                     KGIAWNTQSEMDLLRKLNYTKADGPAKGQPMLNTAIDAAEMILTLAPETNGQVAVKAW
                     AALSEFTGRDHTHLATNKEEEKIRFRDIQAQPRKIISSPTWSGLEDEHVSYNAGYTNV
                     HELIPWRTLSGRQQLYQDHQWMRDFGESLLVYRPPIDTRSVKAVMGRKSNGNPEKALN
                     FLTPHQKWGIHSTYSDNLLMLTLSRGGPIVWMSETDAKELGIEDNDWIEVFNSNGALT
                     ARAVVSQRVPAGMTMMYHAQERIVNLPGSEITQQRGGIHNSVTRITPKPTHMIGGYAQ
                     LAYGFNYYGTVGSNRDEFVVVRKMKNINWLDGEGNDQVQESVK"
     gene            complement(7302..8699)
                     /gene="narK"
                     /locus_tag="OPV72_002984"
     CDS             complement(7302..8699)
                     /gene="narK"
                     /locus_tag="OPV72_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate transporter NarK"
                     /protein_id="HCR9915220.1"
                     /translation="MSHSSAPERATGAVITEWRPEDPAFWQQRGHRVASRNLWISVPC
                     LLLAFCVWMLFSAVAVNLPKVGFNFTTDQLFMLTALPSVSGALLRVPYSFMVPLFGGR
                     RWTAFSTGILIVPCVWLGFAVQDTSTPFSTFIIISLLCGFAGANFASSMANISFFFPK
                     QKQGGALGLNGGLGNMGVSVMQLVAPLVVSLSIFAAFGSHGVEQPDGSQLYLANAAWI
                     WVPFLAIFTLAAWFGMNELATSKASLKEQLPVLKRGHLWIMSLLYLATFGSFIGFSAG
                     FAMLSKTQFPDVQILHYAFFGPFIGALARSAGGAISDRLGGTRVTLINFVLMAIFSGL
                     LFLTLPTGGVGGSFIAFYGVFLALFLTAGLGSGSTFQMISVIFRKLTMDRVKAEGGSD
                     ERAMREAATDTAAALGFISAIGAIGGFFIPKAFGSSLALTGSPVGAMKVFLIFYIACV
                     VITWAVYGRHSKNKK"
     gene            9039..10835
                     /gene="narX"
                     /locus_tag="OPV72_002985"
     CDS             9039..10835
                     /gene="narX"
                     /locus_tag="OPV72_002985"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite two-component system sensor
                     histidine kinase NarX"
                     /protein_id="HCR9915221.1"
                     /translation="MFKRCFSPLTLVNQLALIVMLSTAIGVAGMAVSGWLVQGVQGSA
                     HAINKAGSLRMQSYRLLAAVPLDAKDQKLLDEMEQTAFSPELTRAAERDGQQKQLKAL
                     QDYWHNELSPGLQHAQNAHAVAEDITRFVAGLDRLVTSFDHTTELRIERVVLVHRVMA
                     IFMALLLVFTIIWLRVRLLQPWKQLLSMARAVSQRDFTQRANISGRNEMAALGSALNN
                     MSEELAESYAVLEQRVQEKTAGLEHKNQILSFLWQANRRLHSQAPLCERLSPVLNGLQ
                     NLTQLHDIELRVYDLEDEDNHQEFTCQSDISCDDKGCHLCPRSALPMINGGTTLKWRL
                     TDSHTQYGILLATLPYGRHLSHDQQQLVDTLVEQLTATLALDRHQERQQRLIVMEERA
                     TIARELHDSIAQSLSCMKMQVSCLQMQGDALPESSRELLSQIRNELNCSWAQLRELLT
                     TFRLQLTEPGLRPALEASCQEFSARFGFTVKLDYQLPPRLVPSHQAIHLLQIAREAPS
                     NALKHSHADDVVVTVTQCGKQVKLKVQDNGCGVPENAERSNHYGMIIMRDRAQSLRGD
                     CQVRRRETGGTEVTVTFIPETNFTETQGDTHE"
     gene            10828..11478
                     /gene="narL"
                     /locus_tag="OPV72_002986"
     CDS             10828..11478
                     /gene="narL"
                     /locus_tag="OPV72_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator NarL"
                     /protein_id="HCR9915222.1"
                     /translation="MNNQEPATILLIDDHPMLRTGVKQLVSMAPDISVVGEASNGEQG
                     IDLAESLDPDLILLDLNMPGMNGLETLDKLREKALSGRIVVFSVSNHEEDVVTALKRG
                     ADGYLLKDIEPEDLLKALQQAAAGEMVLSEALTPVLAASLRANRATTDRDVTQLTPRE
                     RDILKLIAQGLPNKMIARRLDITESTVKVHVKHMLKKMKLKSRVEAAVWMHQERIF"
     gene            complement(11479..12903)
                     /locus_tag="OPV72_002987"
     CDS             complement(11479..12903)
                     /locus_tag="OPV72_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460724.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YchO/YchP family invasin"
                     /protein_id="HCR9915223.1"
                     /translation="MPFLLSFVVEVADTLSRIVFRSFSLSLLLLAASGTIRAQAQDPF
                     DQNRLPDLGMMPESHEGEKHFAEMAKAFSEASMKNNDLDTGEQARQFAFGQVRDVVSE
                     QVNQQLESWLSAWGSASVDINVDNEGHFNGSRGSWFIPLQDKQRYLTWSQLGLTQQTD
                     GLVSNVGIGQRWAQDGWLLGYNTFYDNLLDENLQRAGFGAEAWGEYLRLSANYYQPFA
                     DWQTHTATLEQRMARGYDINAQVRLPFYQHINTSVSLEQYFGDSVDLFDSGTGYHNPV
                     ALKLGLNYTPVPLLTMTAQHKQGESGVSQNNLGLTLNYRFGVPLKKQLAASEVAQSQS
                     LRGSRYDTPQRNSLPTMEYRQRKTLTVFLATPPWDLTPGETVALKLQVRSVHGIRHLS
                     WQGDTQALSLTAGTDTRSTEGWTIIMPAWDHREGAANRWRLSVVVEDEKGQRVSSNEI
                     TLALTEPFITMPDDNPHWQPFQEQ"
     gene            13080..13433
                     /locus_tag="OPV72_002988"
     CDS             13080..13433
                     /locus_tag="OPV72_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE/DsrF/TusD sulfur relay family protein"
                     /protein_id="HCR9915224.1"
                     /translation="MQNIVIIANGAAYGSESLFNSLRLAIALREQESHLDLRLFLMSD
                     AVTAGLRGQKPAEGYNIQQMLEILTAQNVPVKLCKTCADGRGITPLPLIDGVEIGTLV
                     ELAQWTLAADKVLTF"
     gene            complement(13513..13743)
                     /gene="chaB"
                     /locus_tag="OPV72_002989"
     CDS             complement(13513..13743)
                     /gene="chaB"
                     /locus_tag="OPV72_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative cation transport regulator ChaB"
                     /protein_id="HCR9915225.1"
                     /translation="MPYKAKSDLPDNVRNVLPAHAQDIYKEAFNSAWEQYKDKADRRD
                     DASREETAHKVAWAAVKNDYEKGEDDKWHKKK"
BASE COUNT         3237 a         3828 c         3605 g         3120 t
ORIGIN      
        1 atgaaaaacg catacaacta tccttattgt cgtttatggc gtgattatat gctgcatcat
       61 cctttttctg cttacaaaaa actcgcacag atgctgaata aacccagaaa caaagagtcc
      121 ggattcagat gccagacatg gcagacccgc tgtaaacgaa acaaggcggc ggtcgataag
      181 gcatttatgc tgcactccgg caaacagcca taaaaaaact ccgccgaagc ggagtttagg
      241 gcatcgagag aaaatcagtg acgcgcacgt acaatctggt atttgcgggt caggtactcg
      301 accggcacgc tccagatatg caccaggcgc gagaatggga ataacaggaa cagcgtcatc
      361 cccagtacca ggtgcatacg gaagataaag gctacaccgt ccagatgtgc ggatgcgcca
      421 ccgtggaagg tcacaactga ctgcgcccac ccgaccagct tcatcatttc actcccgtcc
      481 atatgctggg cggagaacgg aatggtcagc agacccagcg cgcactgaat caccagcaat
      541 gagagaatca aaatatctgc accggtagtg gtggcgcgga cacgtgggct gaacagacga
      601 cgcttgagca gtaaaatacc gccaaccagc gtcagcattc cgcaggcgcc gccggcaatc
      661 atcgccatct tctgcttcac gtcgaccggc agaaaagctt catacatcca gtgcggcgtt
      721 aacatgccca ggaaatgacc ggcgaaaata cccagaatcc caatgtggaa caggtttgac
      781 gccaggttca ttcctttgcg atccagcatc tgactggaag ccgcccgcca ggtgtactgg
      841 ccgtagtcgt aacgtaacca gctaccgatc agaaataccg atccggcaat gtacgggtag
      901 atatcaaaga agaacatatt caggaagtgc attagtgctg tcctccggtg gtgatattca
      961 gatattgcgg cgccacggcc ccggcaaaac gacgctggtg agcggagatt tccgactcgc
     1021 cacacccttg atcggcgaag aatttcacct gctcttcttc ccagaccgca tccaacgcct
     1081 gcggggtatc atcacgtgct tcattcgcaa ttttttcagc cactttgccg ctgtcgataa
     1141 cggtattcgc cagttttaac agcagatcga acagcaccgc ataacggctg tcacgctgtt
     1201 gcaaacgtgc gctgagcaac gccagaatcg gcgcgatatc ctgtaccccc cctaacgctt
     1261 cgcttttcgg caactgcgca aggtattcca gatacagcgg cagatgatcg ggcagttcgc
     1321 ggctgtcgag ctgcaaaccg tgctgttcat actgtgccat caggtcaacc atcgcctgac
     1381 cgcgatcgcg ggattccccg tgtacatgtt caaacagaag cagcgatgtg gcgcgaccac
     1441 ggtcaaacag ttcactataa gcggcctgta catccagcat gtcctgcgcg gttaaatcgc
     1501 gcaggaaaac gcccagagtc tgggcatcct ctttatccag gttctcagat gacgcgagcg
     1561 catcgaacaa ctcctgctga tgctgccaca gggcagcatc cgggtactcg agcagacgcg
     1621 aaacaatgac gagttcaatc atgcgtgcgg ctccgttttg ctggtcacat caacagcgtc
     1681 gatgcggcgg ctgttgaaca gattgaattt ggtatcagac ccgtggcaac catcgccgaa
     1741 ggtaaagcca caaccgcttt tctccgggaa tgcgtcacgc gccagttcac gatggctgct
     1801 cggcaccaca aagcgatctt cgtaattagc aatcgccagg taacgataca tttcctgcgc
     1861 ctgggcttcg cttaaaccca cctcttccag cgcgcgggta tccactttac cgtctacggt
     1921 ttccgcacgt ttgtagtgac gcatcgccag catccgtttc agcgccaaca gtaccggctg
     1981 agtgtcgcca gcggtcaaca gattcgccag gtactgcacc gggatacgca gactgtctac
     2041 atccggcaga ataccgttgc tgcccagttc acccgcgtcg gcggcagact gaatcggtga
     2101 caaaggcggc acgtaccaga ccatcggcag cgtgcggtat tccggatgca gcggcagcgc
     2161 cagcttccag tccatcgcca ttttgtacac tggcgattgc tgcgccgcat cgatcacgct
     2221 ctgcggcacg ccgtccttca gcgcctgctc aatgacagcc ggatcgttcg gatcgaggaa
     2281 cacgtccagt tgacgctggt acagatcttt ttcgttttcc gtactggcag cgctttcaat
     2341 ggcatcggcg tcatacagca gtacgccaag ataacggata cggccaacac aggtttcgga
     2401 gcaaacggtc ggctgacccg cttcgatacg cgggtagcag aagatgcact tctcggactt
     2461 cccgctcttc cagttgaagt aaatcttctt gtacgggcag ccggtgatgc acatacgcca
     2521 gccgcggcac ttgtcctggt cgatcagcac gatgccgtct tcttcacgct tgtagatggc
     2581 accgcttggg caggttgcca cgcacgccgg attgaggcag tgctcgcaca ggcgcggcag
     2641 gtacatcatg aaggtgtttt cgaactggcc gtacatcgcc ttctgcatgt tttcgaaatt
     2701 ctgatctttg gcgcgttttt cgaactcgcc gcccagaatc tcttcccagt ttggcccgct
     2761 ggtaattttg tccatccgct ggccggtaat cagcgagcgc ggacgcgcga tcggctgatg
     2821 tttgctttcc ggcgcagtat gcaggttctg gtagtcgtaa tcaaacggct cgtagtagtc
     2881 gtcgatgccc ggcagatgcg ggttagcgaa gattttaccc agcagcagcg cccggttgcc
     2941 catgcgcggc tgtagtttgc cgttgatttt gcggatccag ccgcctttcc atttttcctg
     3001 attttcccag tcattaggaa aaccaacgcc gggcttactt tctacgttgt tgaaccaggc
     3061 gtattccata ccttcgcgac tggtccagac gtttttacag gtgactgaac aggtatgaca
     3121 gccgatgcac ttatcgagat tcagcaccat gccgacttgt gaacgaattt tcattttacg
     3181 ctctcctgta cctggtcatt gccttcgcca tccaaccagt taatgttctt catcttacgt
     3241 accaccacaa actcatcgcg gttggagccg acggtaccgt agtagttaaa gccgtaggct
     3301 aactgcgcat agccgccgat catatgggtc ggtttcggcg taatacgcgt caccgagtta
     3361 tgaataccgc cgcgctgctg ggtaatttcc gaccccggca ggtttacgat acgttcctgc
     3421 gcgtggtaca tcatggtcat gcccgccggt acacgctggc tgaccactgc gcgtgcggtc
     3481 aatgcgccgt tgctgttgaa gacttcgatc caatcgttat cttcaatgcc cagctctttg
     3541 gcgtcggttt cactcatcca tacaatcggg ccgccacgcg acaaggtcag catcaacagg
     3601 ttatcgctgt aggtcgagtg gataccccat ttctggtgcg gcgtcaggaa gttgagcgcc
     3661 ttctccggat taccgttgga tttacgcccc atcaccgctt tcaccgagcg ggtgtcgatc
     3721 ggtgggcgat acaccagcag actttcgccg aagtcgcgca tccactggtg atcctgatac
     3781 aactgttggc gaccagacag cgtacgccac gggatcagct cgtgaacgtt ggtataaccg
     3841 gcgttataag aaacatgctc atcttccaga ccagaccagg tcgggctgga gataattttg
     3901 cgcggctggg cctgaatatc gcggaagcgg attttctctt cttctttatt agttgccaga
     3961 tgcgtatggt cgcgaccggt aaactcgctc agcgccgccc aggctttcac tgccacctga
     4021 ccgttggttt ccggcgctaa cgtcaggatc atctctgccg cgtcaatcgc cgtgttgagc
     4081 atcggctggc ctttcgccgg accgtccgct ttggtgtaat tgagcttacg cagcaagtcc
     4141 atttcgctct gcgtgttcca ggcaatccct ttcccgccgt tgccgatttt ctccatcagc
     4201 gggccaatag aggtaaagcg ctcataggtg gccggataat cgcgctcaac ggtcatgatg
     4261 tgcggcgcgg ttttccctgg gatcagatcg cattcacctt ttttccagtc tttcacgtcc
     4321 agcggctgtg ccagttcagc ggcagagtcg tgctggatcg gcagcgtcac gacgtcagtc
     4381 tctttaccca ggtggcctac acagacttcg gagaatttct tcgcaatgcc tttgtagatt
     4441 tcccagtcgc ttttcgattc ccaggccgga tctacggcgg cagacagcgg atgaataaac
     4501 ggatgcatat ccgaggtatt catatcgtct ttttcatacc aggtggcggt cggcagtacg
     4561 atatcggagc acaggcaggt gctcgacagg cggaagtcca gcgtcaccac cagatccagt
     4621 ttgccgtcca ggccattgtc acgccattcc acttcttccg gcttcacacc gccctgcttg
     4681 ccgagatcca gcccctgaat accatgctca gtacccagca gatatttcag catatactcg
     4741 tgacctttac cggaagaccc aagcaggttg gaacgccaga taaagaggtt acgtggatgg
     4801 tttttaccgt tttccggctg ctcggcggca aagcgaatcg aaccgtcttt cagggatttg
     4861 acggtataat ctaccggcgt cataccggct ttttccgctt cacgcgcaat atacagcggg
     4921 ttggtgccta actgcggtgc cgacggcaac cagcccatac gttcggcgcg cacattgaag
     4981 tcaatcagat ggccgctata gcgggatttg tccgccatcg gcgacagtaa ctcctcggcg
     5041 gtcaccgtct cgtagcgcca ctggctggag tggttataga agtaagaggt gctgttcatg
     5101 tgacgcgcgg gacgctgcca gtcaagggca aacgccagcg gctgccagcc ggtctgcgga
     5161 cgcagttttt cctggccgac gtagtgcgcc cagccgccgc cgctctgacc aacgcaacca
     5221 cagaacacca acatattgat cagcccgcga tagttcatat cgaggtgata ccagtggttc
     5281 agaccggcgc caacgataat cattgaacgc ccgtgcgttt tgtccgcgtt atcggcgaat
     5341 tcccgtgcga tacggatgat ctgcgcccgc ggcacgccgg tgatctgctc ggcccatgct
     5401 ggcgtatatg ctttggtatc atcataactg gcggcacaat tttcatcgtt caggccgcgt
     5461 tccagaccat agttcgccat ggtcagatcg taaacggtag tgactaacgc tgaagaacca
     5521 tcggccagtt gcagacgttt tgccggcagt ttatgcagca ggacgttatc cagcgccaca
     5581 tgattaaagt actctgaacc ctcgccgccg aaatacggga agcccacgtc agcaatctca
     5641 tcctggctgc ccagcaagct gagctgcaat tcagtttctg caccggtagt cccgtcgcgc
     5701 tgttcgaggt tccatttgcc tttttcgccc cagcggaaac caattgaacc gtttggcgcc
     5761 accatttcac cgttgctgtt gatagcgacg gttttccatt ccgggttatt ttcctgcccc
     5821 agcgaatcaa cgagatcggc agcgcgcagc atacgacctg cggcataata accatcacgc
     5881 tcttcaagca tcaccagcat tggcatgtcg gtatagcgac ggacataatc ggtgaagtac
     5941 tggcgcgggt tgtcgaggtg gaactcgcgc agcatgacgt ggcccatcgc cagcgccatc
     6001 gccgcatcgg tcccctgctt cggcgccagc cacagatcgc acagtttggc gatttcggca
     6061 tagtccggcg tcaccgcgac ggttttagtg cctttgtaac gtacttcggt aaagaagtgg
     6121 gcatccggcg tacgggtttg cggcacgtta gagccccagg cgataatata gctggagttg
     6181 taccagtcag cggattccgg cacgtcggtc tgctcgcccc aggtttgcgg ggaggctggc
     6241 ggcaggtcgc agtaccagtc gtagaagctc aggcaggtac cgccaatcag cgaaagataa
     6301 cgtgcgccgg aagcgtagga aaccatcgac atcgccggaa tgggtgagaa gcccgcgacg
     6361 cggtcagggc cataggtttt cacggtgtac acgttggaag cggcgatcag ctcgttcact
     6421 tcctgccatg aggagcgaac aaagccgcca cgaccacgcg cctgtttgaa gcttttggct
     6481 ttatcggcat cttcaatgat ggaggcccat gcctctaccg gatcgcgatg cagttttttc
     6541 gcctcgcgcc acatcttcat cagacgtttg cgcattagcg gatatttcag tcggttagcg
     6601 ctgtagagat accaggagta acttgccccg cgcgggcagc cgcgaggttc atggtttggc
     6661 atatcaggac gggtgcgcgg gtaatcggtt tgctgtgttt cccaggtcac cagaccattt
     6721 ttgacataaa ttttccagct acaagaaccg gtgcagttca ccccatgggt tgagcgcaca
     6781 attttgtcat gctgccaacg ttggcggtat ccgtcctccc agtcccggtt tgtttcgaga
     6841 agctggccgt gcccatcggc aaaggtttcg cccttctgct tgaagtagcg aaaccggtcc
     6901 aggaatttac tcatcgggtt tctcctgtgt ggaaccttac ggctctctga taaatcgaca
     6961 ttgcttaact aagggcgaag gtaacgcgct gaatgggcgt gagaattgat aacgatcaag
     7021 gcggacaggg atgcaaatgg cgcgcaaacc tccggcatac tccttttgga ggaggagttt
     7081 tatttatata tattactgat ttaattacat aaaattaaat ttacgcacga catgaatgtt
     7141 aaattttcaa caagtgggta ttaaggggta tccccctgga tgaccgataa aaatgtgcgt
     7201 ggtcagtcct gtcgcgcctc tcttcttgac tataagtatg ttgtaactaa atgcgggtaa
     7261 aaaaaagcgc ggtctaacgc cgcgcaaagg ataatcaaaa gttacttttt atttttagaa
     7321 tgacgtccat ataccgccca ggtaataacg acgcaggcga tatagaaaat aagaaagact
     7381 ttcatcgcgc cgactggcga accggttaat gctaaagatg aaccaaacgc tttcggaata
     7441 aaaaagccgc caatcgcgcc aatcgcggaa ataaagccca gcgccgccgc cgtatcggtc
     7501 gccgcttcac gcatggctct ttcgtccgac ccgccttccg cttttacccg gtccatcgtc
     7561 agtttacgga agataacgga gatcatctgg aaggtagaac cactccccag ccccgccgtc
     7621 aggaatagcg ccagaaatac cccgtagaat gcgataaagc taccgccaac gccgccagta
     7681 ggtaatgtca ggaacagcag accgctgaaa atcgccatca ggacaaagtt gataagcgtg
     7741 acgcgagtcc cccccagacg gtcagaaatt gcgccgcctg ccgaacgcgc cagcgcgccg
     7801 ataaacggac cgaaaaacgc ataatgcagg atctgcacat ccgggaattg cgttttagac
     7861 agcatagcga accccgcgga gaaaccgata aacgatccga aggtcgccag atacagcaga
     7921 ctcatgatcc acagatgacc acgtttgagc accggcagtt gctcttttag cgaggcctta
     7981 gacgtcgcca gttcgttcat gccgaaccac gctgccagcg taaaaatggc caggaaaggc
     8041 acccaaatcc aggctgcgtt cgccagatag agctgagaac cgtccggctg ctctacaccg
     8101 tggctgccaa aggcggcaaa gatagagagc gaaaccacca gcggcgcaac cagctgcatc
     8161 acgctcacgc ccatattgcc cagaccgccg ttcagaccca gcgcgccgcc ctgcttttgt
     8221 ttaggaaaga aaaagctgat gttcgccata ctggaggcaa agttcgcgcc ggcaaaacca
     8281 cacagcaagg aaataataat gaaagtgcta aatggcgtac tggtatcctg aacggcaaag
     8341 cctaaccata cgcaaggcac gatgaggata ccggtactga acgctgtcca gcgacgtccg
     8401 ccaaatagcg gcaccataaa ggagtaaggc acccgtagca gcgcgccgga aacagatggc
     8461 agcgcagtca acataaagag ctgatcggtc gtaaaattaa atcccacttt cggcaggttc
     8521 accgccactg cgctgaatag catccagacg caaaacgcca gcagtaaaca cgggacagaa
     8581 atccacaaat tacggctagc gacacgatgg ccgcgctgct gccagaacgc cggatcttcc
     8641 ggacgccatt ccgtgataac agcgccagtt gccctttccg gggcggatga gtgactcata
     8701 gacacctctg attcttgatt tgatgtctgc cacattaggg tttactgccg aaggtaagtt
     8761 gatataaatc aaaggaaaag tcgtcatcac cggcgactaa aaatagttat tacccttaat
     8821 gagtaggcta ttttggtaaa aaagctgtgg tttttcacca tgctgtgtct gtctactcct
     8881 tcccgtcgca gatacctctt tacggcggca attaaggagt aactcgttat aggtatgggt
     8941 atactccgct gtatcgttga gaatagcggc acagccgatt gacgccccct tttttgctac
     9001 gttttttcgg cgacattacc ccgaagaaag aaggtaacat gtttaaacgg tgtttctctc
     9061 ctcttacgct ggttaaccaa ctggcgctga ttgtcatgct ctctaccgct atcggcgtgg
     9121 cggggatggc ggtttccggc tggctggttc agggcgtgca gggtagcgct catgcgatta
     9181 ataaagcggg ctcattgcgt atgcaaagct atcgactact ggccgctgtc ccgctggatg
     9241 ctaaagatca aaagctgctg gatgagatgg agcaaacggc attcagccct gaactgaccc
     9301 gcgccgctga gcgagacggg cagcagaagc agcttaaagc gttgcaggat tactggcata
     9361 acgaactctc gccagggcta cagcacgcgc aaaacgcgca cgcggtcgca gaagatatca
     9421 cgcgctttgt ggcgggcctg gatcgcctgg tgacgtcgtt cgaccatacg actgaattgc
     9481 gtatcgaacg agtggtatta gttcaccggg taatggcgat ctttatggcg ctattgctgg
     9541 tatttacgat tatctggcta cgtgttcgcc ttttgcagcc ctggaaacag ttgttatcaa
     9601 tggcgcgcgc cgtcagtcag cgcgacttta cccaacgtgc caatatcagt ggacgcaatg
     9661 agatggccgc gttgggttct gcgctcaata atatgtctga agaactggcc gaaagttatg
     9721 cagtactgga acagcgagta caggaaaaaa cagccggtct ggaacataaa aaccagattc
     9781 tctcgttttt gtggcaagcc aaccgccgac tgcattcaca ggctccgcta tgtgaacgtc
     9841 tttcaccggt actgaatggc ctgcaaaatt taacccagtt gcatgatatt gagctgcgag
     9901 tctatgacct ggaagatgaa gataatcacc aggaatttac ctgtcagtcg gacatcagtt
     9961 gcgatgataa aggctgccac ctttgcccac gtagcgccct gccgatgatt aacggcggca
    10021 ccaccttaaa atggcggctc accgactctc acacccaata cggtattttg ctggcgacgc
    10081 tgccctatgg acgccatctc agccacgatc agcaacagtt ggtggacacg ctggttgaac
    10141 agcttaccgc gactctggcg ctcgacaggc atcaggagcg ccagcagcgg ttgattgtca
    10201 tggaagagcg tgccaccatt gcccgcgaac tgcatgattc tattgcccag tcgctctctt
    10261 gtatgaagat gcaggtgagc tgcctgcaaa tgcagggcga cgcgttaccg gaaagcagcc
    10321 gtgagttact cagccaaatt cgcaatgagc tgaactgctc ctgggcgcaa ctgcgcgaac
    10381 tgttaaccac tttccgctta cagttgacgg aacccgggct acgtccggcg ctggaggcaa
    10441 gctgccagga gttcagcgcc cggtttggct ttacggtaaa actggattat cagcttcccc
    10501 cccgcctggt gccatcacac caggcgatac acctgttgca aattgccagg gaagccccca
    10561 gcaacgccct taaacactct catgccgacg atgtggtggt gacagtgacg caatgtggca
    10621 aacaggtcaa actaaaagtg caggacaatg gctgcggcgt cccggaaaac gccgaacgca
    10681 gtaatcacta cggcatgatc atcatgcgcg atcgggcgca aagtttgcgc ggcgattgcc
    10741 aggtacgccg acgcgagact ggcggaacag aggtcactgt tacttttatt ccagaaacaa
    10801 acttcacaga aacccaggga gatacccatg aataatcagg aaccggcaac catcctgtta
    10861 atcgatgacc atccgatgct acgcacgggt gtaaagcagc ttgtgagtat ggcgcccgat
    10921 atcagcgtgg tcggagaagc cagcaacggt gagcagggta ttgacctggc ggaatcgctc
    10981 gatcccgatc tgatcctcct tgatttgaat atgccgggaa tgaatggtct cgaaacgctg
    11041 gataaattac gcgaaaaagc gctgtcagga cgtattgtcg ttttcagcgt atccaaccat
    11101 gaagaagatg tcgtcacggc gctaaagcgc ggcgcggatg gttatctgtt gaaagacata
    11161 gagccggagg acttgctcaa agcgttacaa caggccgccg ccggcgaaat ggtattaagt
    11221 gaagcgttaa cgccggtact ggcggccagc ctgcgggcca accgcgctac caccgatcgc
    11281 gatgtgacgc aactcacccc gcgtgagcgc gatattctga agctcatcgc gcagggattg
    11341 ccaaataaga tgattgcccg gcgtctggat atcaccgaaa gtacggtcaa agtgcacgtg
    11401 aaacatatgc tcaagaaaat gaagctgaaa tcgcgcgtgg aggccgccgt ctggatgcat
    11461 caggaacgca tcttttaatt attgctcctg gaacggttgc caatgcggat tatcgtccgg
    11521 catcgtgata aacggttcag tcagcgcgag cgtgatctca ttggaagaga cacgctgacc
    11581 tttttcatcc tcaaccacca ccgataaacg ccagcgattt gccgcgcctt cgcggtgatc
    11641 ccaggccggc ataatgattg tccagccctc ggtactgcgg gtgtccgttc ctgccgtcaa
    11701 acttaatgcc tgtgtatcgc cctgccagct caaatgacga ataccgtgca cgctgcgcac
    11761 ctgcaatttt aacgcaaccg tctcaccagg cgtaagatcc cagggcggcg tcgccagaaa
    11821 aaccgttaac gttttacgct gccgatactc cattgtcggc agcgagttac gttgcggcgt
    11881 atcatagcgg ctaccgcgta atgactggct ttgcgccact tcactggcgg caagctgctt
    11941 tttgagcggc acgccgaagc ggtagttaag cgtcagcccc aggttattct gactgacccc
    12001 gctctcgccc tgtttgtgct gggcggtcat agtaagcaaa ggtactggcg tatagttgag
    12061 acccagtttt aacgcgacag gattgtgata ccccgttccg gagtcaaaca gatccacgct
    12121 atcgccaaag tactgctcca gactaacgct ggtattgata tgctggtaaa acggcagccg
    12181 cacttgcgcg ttgatatcat atccgcgcgc cattcgctgt tctaaggtcg ccgtatgcgt
    12241 ctgccagtcg gcaaaaggct gataatagtt ggcggataaa cgcaaatatt ctccccacgc
    12301 ctccgcgcca aagccggcgc gctgcagatt ttcatccagc agattatcgt aaaaggtatt
    12361 atagccaaga agccagccat cctgcgccca gcgctgtcct atgccaacgt tgcttaccag
    12421 tccgtcagtc tgttgcgtaa gaccaagctg gctccaggtc agatagcgct gtttatcctg
    12481 taaagggata aaccagcttc cgcgactgcc gttaaaatga ccttcgttat cgacgttaat
    12541 atccacgctg gcgctgcccc aggctgatag ccagctttca agctgctggt taacctgctc
    12601 gctgaccaca tcgcgtacct gtccgaaagc gaattgccgc gcctgttcac cggtatccag
    12661 atcgttattt ttcatgctgg cttcgctaaa cgctttggcc atctcggcaa aatgcttttc
    12721 cccttcgtgg gattccggca tcatgcctaa atccggcaga cggttttgat cgaaagggtc
    12781 ttgcgcctgc gcacggatcg taccgctggc agccagcaag agaagcgaga gtgagaatga
    12841 acgaaaaaca atacggctca acgtgtcggc aacttctaca acaaaagata agaggaatgg
    12901 catcagagta aaccataacg tgtccggaca ggttttgcag ccttttctcg tgtttccagg
    12961 aatatcctta ttttttccgc agagcgtccc gggattttct ccacgcattt ggcggtaccc
    13021 ggttcccgag gtaacataac gccattgccg acaaaatttc tcaaggagaa gggttatcca
    13081 tgcaaaatat cgtcattatc gctaacggcg ccgcctacgg cagcgaatca ttatttaata
    13141 gcctgcgtct ggccattgcg cttcgcgagc aggaaagcca tctcgattta cgcctgtttt
    13201 tgatgtcaga tgccgtaacc gcagggttac gcggtcaaaa accagccgaa ggctacaata
    13261 ttcagcaaat gctggaaatt ctaaccgcgc aaaacgtacc ggtaaaatta tgcaaaacct
    13321 gtgcggacgg acgtggtatc actcccctgc cgctgattga cggtgtggaa atcggaacgc
    13381 tggtcgagct ggcgcaatgg acgctggcgg cggacaaagt gctgacattt tgaatctgta
    13441 cgcgggaaaa gctcccgcgt caggatagac ttccggcaag aaaatcaggc taacgcgtga
    13501 gtaataccgc gtttattttt tcttatgcca tttatcatcc tcgccttttt cataatcgtt
    13561 tttaaccgcc gcccaagcga ctttgtgtgc ggtttcctcg cgactggcgt catcacgacg
    13621 atcggcttta tctttatatt gctcccaggc gctattaaac gcttctttgt aaatgtcctg
    13681 ggcatgggct ggaagaacat tccgcacatt atcgggtaaa tcacttttgg ctttatacgg
    13741 catcagcgcc tccgtcttca gggaaaacat taagtgtggt aaacaatgcg
//
LOCUS       DAJVBX010000123        13786 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.123, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000123 DAJVBX010000000
VERSION     DAJVBX010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 13786)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13786)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13786
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.123"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            60..1121
                     /locus_tag="OPV72_002990"
     CDS             60..1121
                     /locus_tag="OPV72_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncE family protein"
                     /protein_id="HCR9915226.1"
                     /translation="MHLRHLFSPRLRGSLLLGSLLVASSFSTLAAEDMLRKAVGKGAY
                     EMAWSQQENALWLATSQSRKLDKGGVVYRLDPVTLEITQAIHNDLKPFGATINAATQT
                     LWFGNTINSAVTAIDAKTGDVKGRLVLDARKRTEEVRPLQPRELVADAATNTIYISGV
                     GKESAIWVVDGETIKLKTTIENTGKMSTGLALDSKAQRLYTTNADGEFITIDTASNKI
                     LSRKKLLDDGKEHFFINLSLDTAGHRAFITDSKATEVLVVDTRNGNILAKIAAPASLA
                     VLYNPTRNEAYVTHRQAGQVSVIDAKTYNVVKTFDTPTYPNSLALSADGKTLYVSVKQ
                     KSTREQEATQPDDVIRIAL"
     gene            1266..1487
                     /locus_tag="OPV72_002991"
     CDS             1266..1487
                     /locus_tag="OPV72_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgdI/YgdR family lipoprotein"
                     /protein_id="HCR9915227.1"
                     /translation="MKKLFICSGLGMMFFMLAGCTTNYVMTTKNGQTIVTQGKPQLDK
                     ETGMTSYTDQEGNQREINSNDVAQLIKAD"
     gene            complement(1564..3057)
                     /gene="ansP"
                     /locus_tag="OPV72_002992"
     CDS             complement(1564..3057)
                     /gene="ansP"
                     /locus_tag="OPV72_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-asparagine permease"
                     /protein_id="HCR9915228.1"
                     /translation="MKTQTTHAAEQHAAKRRWLNAHEEGYHKAMGNRQVQMIAIGGAI
                     GTGLFLGAGARLQMAGPALALVYLICGIFSFFILRALGELVLHRPSSGSFVSYAREFL
                     GEKAAYVAGWMYFINWAMTGIVDITAVALYMHYWGAFGDVPQWVFALGALTIVGTMNM
                     IGVKWFAEMEFWFALIKVLAIVIFLVVGTIFLGTGQPLEGNATGFHLITDNGGFFPHG
                     LLPALVLIQGVVFAFASIELVGTAAGECKDPQTMVPKAINSVIWRIGLFYVGSVVLLV
                     LLLPWNAYQAGQSPFVTFFSKLGVPYIGSIMNIVVLTAALSSLNSGLYCTGRILRSMS
                     MGGSAPKFMAKMSRQHVPYAGILATLVVYVVGVFLNYLVPSRVFEIVLNFASLGIIAS
                     WAFIMVCQMRLRQAIKEGKAADVSFKLPGAPFTSWLTLLFLLSVLVLMAFDYPNGTYT
                     IASLPLIAILLVAGWFGVRRRVAEIHRTAPVTADSTESVVLKEEAAT"
     gene            3570..4202
                     /locus_tag="OPV72_002993"
     CDS             3570..4202
                     /locus_tag="OPV72_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector protein steA"
                     /protein_id="HCR9915229.1"
                     /translation="MPYTSVSTYARALSGNKLPHVAAGDYENKLSTKIMKGILYVLTA
                     GLAYGFTRVIEHYCNVTPKVDEFCANAGNIHNHLADAVRDEQFIIDVELSDGRMLTFE
                     QLSLMAGREPIVRISDGEHSVEVKGSFEDICMRLEEGFFEAPAYYGYDIDEKYKTVRE
                     RIAAYNALPQALGAIPSLKYYTDRANDMPEAKAQRAADIKDRYHNYLDKY"
     gene            4485..5330
                     /gene="nhoA"
                     /locus_tag="OPV72_002994"
     CDS             4485..5330
                     /gene="nhoA"
                     /locus_tag="OPV72_002994"
                     /EC_number="2.3.1.118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-hydroxyarylamine O-acetyltransferase"
                     /protein_id="HCR9915230.1"
                     /translation="MTSFLHAYFTRLNCQPLGGPTVEALRTLHLAHNCAIPFENLDVL
                     LPREIQLDETALEEKLLYARRGGYCFELNGLFERALRDIGFNVRSLLGRVILSHPASL
                     PPRTHRLLLVDVEDEQWIADVGFGGQTLTAPLRLQAEIAQQTPHGEYRLIQEGSTWIL
                     QFRHHEHWQSMYCFDLGVQQQSDHVMGNFWSAHWPQSHFRHHLLMCRHLPDGGKLTLT
                     NFHFTRYHQGHAVEQVNIPDVPSLYQLLQQQFGLGVNDVKHGFTEAELAAVMAAFDTH
                     PEAGK"
     gene            complement(5366..6259)
                     /locus_tag="OPV72_002995"
     CDS             complement(5366..6259)
                     /locus_tag="OPV72_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family isomerase"
                     /protein_id="HCR9915231.1"
                     /translation="MKPQIYHVDAFTSEPFRGNSAGVVLHADTLSDAQMQLIARELRH
                     SETAFLLKSEESDVRIRYFTPTVEVPICGHATVAAHYVRATVLGLGNTTVWQTSLAGR
                     HRVEIHAEHNDYRITLEQGQPSFEPPLVGEIRAAIITALNLTEDDIVPGAPIQVASTG
                     HAKVMILLKPDVDIDALSPNLAALTAISQQIGCNGFFPFQIRPGKNETDGRMFSPAIG
                     IVEDPVTGNANGPMGAWLVHHGLMAHDGKTLQIQGHQGRALGKEGTVDVTVTIRDNQP
                     ENVTISGQAVILFHAEWAITF"
     gene            complement(6355..6993)
                     /gene="narJ"
                     /locus_tag="OPV72_002996"
     CDS             complement(6355..6993)
                     /gene="narJ"
                     /locus_tag="OPV72_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001767506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase molybdenum cofactor assembly
                     chaperone"
                     /protein_id="HCR9915232.1"
                     /translation="MQILKAIGLLMEYPDDELWECRDEALALIQHDAPMLANFTRELL
                     YAPLLDKQAEWCEVFDRGRATSLLLFEHVHAESRDRGQAMVDLLSQYETVGLHLNCRE
                     LPDHLPLYLEYLSVLPEAEAREGLQNIAPILALLGGRLKQRGAPWYQLFDALLTLAGS
                     TLTSDSVTKQIVQESRDFSCSSRSPVWFMSGARRSSISPVATRLFVPAANSL"
     gene            complement(6993..8537)
                     /gene="narH"
                     /locus_tag="OPV72_002997"
     CDS             complement(6993..8537)
                     /gene="narH"
                     /locus_tag="OPV72_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit beta"
                     /protein_id="HCR9915233.1"
                     /translation="MKIRSQVGMVLNLDKCIGCHTCSVTCKNVWTGREGMEYAWFNNV
                     ETKPGIGYPKNWEDQQEWQGGWVRDVNGKIRPRLGGKMGVISKIFANPVIPQIDDYYE
                     PFTFDYQHLHTAPESKHQPTARPRSLIDGKRMDKVIWGPNWEELLGGEFEKRARDRNF
                     DNIQKEMYGQFENTFMMYLPRLCEHCLNPSCVATCPSGAIYKREEDGIVLIDQDKCRG
                     WRLCISGCPYKKIYFNWKSGKSEKCIFCYPRIESGQPTVCSETCVGRIRYLGVLLYDA
                     DRIEEAASTEHETDLYERQCDVFLNPHDPAVIEEALKQGIPQNVIDAAQRSPVYKMAM
                     DWKLALPLHPEYRTLPMVWYVPPLSPIQSYADAGGLPHNGNILPAVETLRIPVQYLAN
                     MLSAGDTGPVIRALKRMMAMRHYMRSQTVEGVTDTRAIDEVGLSVQQVEEMYRYLAIA
                     NYEDRFVIPTSHREMARDAFPERNGCGFTFGDGCHGSDTKFNLFNSSRIDAINITEVR
                     DKAEGE"
     gene            complement(8534..12262)
                     /locus_tag="OPV72_002998"
     CDS             complement(8534..12262)
                     /locus_tag="OPV72_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit alpha"
                     /protein_id="HCR9915234.1"
                     /translation="MSKLLDRFRYFKQKGDTFADGHGQMMHTNRDWEDSYRQRWQFDK
                     IVRSTHGVNCTGSCSWKIYVKNGLVTWETQQTDYPRTRPDLPNHEPRGASYSWYLYSA
                     NRLKYPLVRKRLIELWREALSRHSDPVLAWESIMNDPQKCQSYKQVRGHGGFIRSNWK
                     ELNQLIAAANVWTIKTYGPDRVAGFSPIPAMSMVSYAAGTRYLSLLGGTCLSFYDWYC
                     DLPPASPMTWGEQTDVPESADWYNSAYIIAWGSNVPQTRTPDAHFFTEVRYKGTKTIA
                     ITPDYSEVAKLCDQWLAPKQGTDSALAMAMGHVILKEFHLDNPSDYFLNYCRRYTDMP
                     MLVLLDERADGSYVPGRMMRASDLVDGLGEANNPEWKTVALNSTGELVAPNGSIGFRW
                     GEKGKWNLEPVAAGVETELSLSLLGQHDDVAGVAFPYFGDNENPHFRSVRQEPVLVRQ
                     LPVKRLALADGSERMVVSVYDLVLANYGLDRGLDDGHSANNYNDVKAYTPAWGEQITG
                     VPRRHIETIAREFAETAHKTHGRSMIILGAGVNHWYHMDMNYRGMINMLVFCGCVGQT
                     GGGWAHYVGQEKLRPQTGWLPLAFALDWNRPPRQMNSTSFFYNHASQWRYEKLTAQEL
                     LSPLADPTKFTGHLIDFNVRAERMGWLPSAPQLNLNPLSVKASADKAGLSAADYTMQV
                     LKSGAIRFACERPDSGHNHPRNLFVWRSNLLGSSGKGHEYMLKYLLGTDSGIQGEALG
                     SSEGIKPEEVEWQSAAIEGKLDLLVTLDFRMSSTCLFSDIVLPTATWYEKDDMNTSDM
                     HPFIHPLSAAVDPAWESKSDWEIYKGIASAFSEVCVGHLGQETDVVLHPLQHDSPAEL
                     AQPFDILDWRKGECELIPGKTAPNIVVVERDYPATYERFTSLGPLLDKLGNGGKGIAW
                     NTQDEVDFLGKLNYTKHDGPAKGRPRIDTALDASEVILALAPETNGQVAVKAWQALGE
                     MTGREHTHLAINKEDEKIRFRDIQAQPRKIISSPTWSGLESEHVSYNAGYTNVHELIP
                     WRTLSGRQQLYQDHAWMRAFGESLVAYRPPIDTRSVSEMREIPPNGFPEKALNFLTPH
                     QKWGIHSTYSENLLMLTLSRGGPIVWISEADARELGIEDNDWIEAFNANGALTARAVV
                     SQRVPPGMTMMYHAQERIMNIPGSEVTGMRGGIHNSVTRVCPKPTHMIGGYAQLAYGF
                     NYYGTVGSNRDEFIMIRKMKNINWLDDEGRDQVQEAKK"
     gene            complement(12354..13742)
                     /locus_tag="OPV72_002999"
     CDS             complement(12354..13742)
                     /locus_tag="OPV72_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NarK family nitrate/nitrite MFS transporter"
                     /protein_id="HCR9915235.1"
                     /translation="MTRQNENYNRYLLSDWRPENPAFWENKGKGIARRNLWISVSCLL
                     LAFCVWMLFSAVAVNLNKIGFDFTTDQLFLLTALPSLSGAILRVPYSFMVPLFGGRKW
                     TVLSTVILIIPCAWLGFAVQNPATPFGVFILIALLCGFAGANFASSMGNISFFFPKAR
                     QGSALGINDGLGNLGVSVMQLIAPLVIFLPIFTFLGVRGVPQPDGSLLALTNAAWIWV
                     PLLAVATLAAWFGMNDIGSSKASVASQLPVLKRLHLWLLSLLYLATFGSFIGFSAGFA
                     MLAKTQFPDVNILQLAFFGPFIGALARSAGGVISDKFGGVRVTLINFIFMALFTALLF
                     LTLPGSGAGSFSAFYLVFMGLFLTAGLGSGSTFQMIAVIFRQITLYNVKLRGGSDEQA
                     QREAVTDTAAALGFISAIGAVGGFFIPKAFGTSLALTGSPVGAMKIFLLFYIACVLLT
                     WLVYGRLKPKQQ"
BASE COUNT         3380 a         3633 c         3598 g         3175 t
ORIGIN      
        1 atcccgcgca gcgaagtagt gtgaagcagc tatacacgtt tttatcaaaa ggagtcgtca
       61 tgcacttacg tcatcttttt tcgccgcgcc tgcgtggttc tttattgtta ggttcgctcc
      121 tcgtcgcatc ctcatttagc acgctggcgg cggaagacat gctgcgtaaa gcggtaggca
      181 aaggcgctta tgagatggcc tggagtcagc aagaaaacgc gctctggctg gctacatcgc
      241 aaagccgtaa actggataaa ggcggcgtag tttatcgtct cgacccggtg acgctggaaa
      301 tcacgcaagc gattcataac gatctcaagc cgttcggcgc caccatcaat gccgcgaccc
      361 aaacgctgtg gtttggcaat accattaaca gcgcagttac cgcgattgat gccaaaacgg
      421 gtgatgtaaa aggtcgtctg gtacttgatg cgcgcaaacg tactgaagag gttcgtccgt
      481 tacagccccg tgagctggtt gccgatgcgg cgaccaacac gatctacatt agcggtgttg
      541 gtaaagagag tgctatttgg gtagtggatg gcgaaaccat caaactgaaa acgacgatcg
      601 aaaataccgg caaaatgagt acgggtctgg cgctcgacag taaagcacaa cgcctgtaca
      661 ccaccaatgc ggatggcgaa tttatcacca tcgataccgc cagcaataaa attctcagtc
      721 gtaagaagtt gctggatgac ggtaaagaac acttctttat taatctgagt ctcgataccg
      781 caggtcatcg cgcgtttatc accgactcga aggcaactga ggttctggtt gtcgataccc
      841 gtaatggcaa tattcttgcc aaaatcgcgg cgcctgcctc tttggccgtc ctgtataatc
      901 cgacacgtaa cgaggcgtat gtgacgcacc gtcaggcagg gcaggtcagc gtgatcgatg
      961 cgaagaccta taacgttgtt aaaacgttcg atacgccgac gtacccgaat agcctggcgc
     1021 tatcggcaga cggtaaaacg ctctacgtca gcgtgaagca gaaatcgaca cgtgaacaag
     1081 aagcgacgca gccggatgat gttattcgca ttgctctgta aatagggtat ggagggggaa
     1141 acccctccag tcatctcttt aaacgcaccg atacgcctcg ttaaaccccg ccgatagcct
     1201 gatgattctg tgagaattac actacctttt tgcagtcgtt aactcattat attcacgagg
     1261 aaaatatgaa aaagttattt atatgctcag gtttgggcat gatgtttttt atgcttgcgg
     1321 gttgtacaac caactatgtg atgacgacga agaatgggca aacgatcgta actcagggta
     1381 agccgcagtt agataaagag acgggaatga ccagttatac cgatcaggaa ggcaaccagc
     1441 gggaaattaa cagcaatgat gtggcgcagt tgattaaggc tgactaagca ttgggcgcga
     1501 tgcggtgttg gcggcaacgc gcattaaacc cggcaggcct gaggctgccg gggaagggta
     1561 atgttatgtc gctgcttctt ctttcaatac gacactctct gtcgaatccg ccgtcactgg
     1621 cgcagtgcga tggatctccg ccacgcgacg tcgcacgcca aaccagccgg cgaccagcag
     1681 aatagcgatc agcggcaacg aggcgatagt gtaagttcca ttcgggtagt caaacgccat
     1741 gagtaccagc acgcttaata aaaacagcag cgttaaccag gaggtgaaag gcgcgccggg
     1801 cagtttaaaa ctgacgtctg cggctttgcc ttcttttatc gcctggcgta aacgcatctg
     1861 gcacaccatg ataaacgccc acgacgcgat aatgccgagc gaggcaaaat taagaacgat
     1921 ctcaaacacg cgggagggga ccagataatt aaggaacacg ccgaccacgt aaaccaccag
     1981 agtcgccaga atacccgcat agggcacatg ctgacggctc attttcgcca tgaatttcgg
     2041 cgcggacccc cccatcgaca ttgaacgtaa aattctcccc gtacagtaaa gcccggagtt
     2101 caggctggaa agcgcggcgg ttaacaccac gatattcata atactgccga tataaggcac
     2161 gccaagttta gaaaagaagg tgacaaacgg actttgcccc gcctggtagg cgttccacgg
     2221 cagcagcaaa accagcaata cgaccgatcc tacatagaaa agaccaatac gccagatcac
     2281 gctattgatg gcttttggca ccatcgtctg tggatctttg cactccccag cggcggtacc
     2341 gaccaattca atcgaagcaa aagcgaacac cacgccctga atcagtacca gcgcgggcaa
     2401 caggccgtgc gggaaaaagc cgccattatc tgtaatcagg tgaaaaccgg tggcattacc
     2461 ctcaagcggt tgaccggtac cgagaaaaat cgtgcctacc accaggaaga taacaatggc
     2521 gagtactttt atcagcgcga accagaactc catttcggca aaccatttta cgccgatcat
     2581 gttcatggta ccgacaatgg ttaacgcgcc gagcgcaaac acccattgcg gaacgtcgcc
     2641 aaatgcgccc cagtagtgca tgtataacgc cactgcggtg atatcgacga tcccggtcat
     2701 cgcccagtta ataaagtaca tccagcctgc tacgtaggcc gctttttcac ccaaaaattc
     2761 acgggcgtag gagacgaagc tcccgctgga agggcgatgc aataccagtt cgcccagcgc
     2821 gcgtaaaatg aaaaaagaaa aaatgccgca tatcagatag accagcgcca gtgccggtcc
     2881 ggccatttgc aatcgggcgc ctgcacctaa aaataaaccg gtgccaatcg cgccgccgat
     2941 agcaatcatc tgaacctgac gattccccat cgctttgtga tacccctctt catgggcgtt
     3001 cagccagcgt cgtttcgccg catgttgttc tgcggcgtgc gtagtctgtg ttttcattac
     3061 gttacctgtt atagcctgtc ctgacagaaa aattccttat gccgcgacgg gcgctcacca
     3121 atcgattgcc tgcaatggcg aatgccgctt ttccctgatt ctgtgacagg gataaaaccg
     3181 ccggcggagc atcctacctg caattgttaa atgacgcaaa acatacggaa agaacaaaat
     3241 gaggatgtcg tgtttatttg tgcggtcaga tgtggtgcgg tgtggtcacg attcagccag
     3301 ataagctttc agcacaaatc cgcagtgatt gcgttgcgca ataattaatc agagttaatc
     3361 cctgcaggga tttatggtca tagatatgac ctcgaacgat aaaccacctg acgatattga
     3421 agcagcataa gatcaggccg ttgcgcctgt tattctcatt ttctcctgaa aatgtatgcc
     3481 tttgagcaat tttgttgatt gacatatcgt cataatgaga gaggagtagg acatataaag
     3541 ctattgagca aaatttgaag gagcaggata tgccatatac atcagtttct acctatgcca
     3601 gagctttatc aggaaataag ctacctcatg ttgctgcagg agattatgaa aataaattat
     3661 caacaaaaat catgaaaggc atcttgtatg tgcttaccgc aggactggcc tacggattta
     3721 cgcgagtaat tgaacattat tgcaatgtta cgcctaaagt tgatgagttc tgtgccaatg
     3781 cagggaatat ccataatcac cttgcagatg ctgtacgtga tgaacaattt attatagatg
     3841 tcgagctttc tgatggtcgg atgttaacat tcgaacaact ctcgctgatg gctggacgtg
     3901 agccaatcgt caggatatcg gatggcgaac atagcgttga ggttaagggg tcctttgaag
     3961 atatctgtat gagactggaa gagggctttt ttgaagcgcc agcatactat ggttatgata
     4021 ttgatgaaaa atataaaacc gtcagagagc gaatagcagc atataatgcc ttacctcagg
     4081 cattaggcgc cattccgagt ttaaaatatt ataccgatcg ggccaacgac atgccggagg
     4141 cgaaagcgca acgggcggcc gacataaaag atcgttacca taactattta gacaagtatt
     4201 aaaaagcgtt tatgtttagc cagttttgtt agaaatcaga ctcgctgagc tggcgttaaa
     4261 aattttaaca cgccgctatt ttggcggcgt gtcgcaaaga gattctcaga acccgatttc
     4321 cgtttatacg ccaaaattct acgtaccccg gcggctgtag ccggcctgtc ttattttttc
     4381 aaaagtatcc aacgctattc cacggatagg gtatcctgtt gcgcagcgat atccacctca
     4441 gcctgtgtgc cgaacgcaag cattaatgtt aatggaagcc tcagatgacc tcttttttac
     4501 atgcttattt tacgcgatta aattgtcagc cgttgggggg tcctacggtt gaagcgctca
     4561 gaacgcttca cttagcgcac aactgcgcga ttccttttga aaatctggat gtgctactgc
     4621 ctcgtgaaat acagcttgat gagacggcac tagaggagaa actgctttat gcccgacgcg
     4681 gtggatactg ttttgaactg aatggcctgt ttgaacgcgc gttacgcgac atcggtttta
     4741 acgtccgaag cttattgggg cgggtcattc tgtctcatcc cgccagttta ccgccgcgca
     4801 cgcaccgttt gctgctggtt gatgttgagg atgagcagtg gatcgcggac gtggggtttg
     4861 gcggccaaac gctaaccgca ccgcttcgtc tgcaggctga aattgcccag caaacgccgc
     4921 atggcgaata ccgcctgata caggagggga gcacatggat tttacaattc cgccaccatg
     4981 agcactggca gtcgatgtac tgttttgatc tgggggtgca gcagcagagc gatcatgtaa
     5041 tgggcaattt ctggtcggct cactggccgc aatcccattt tcgtcatcat ttgttgatgt
     5101 gccgccattt gcctgatggc ggcaagctga cattaacgaa tttccacttc acgcgttacc
     5161 accagggaca tgccgttgaa caggtcaata taccggatgt accgtcgttg tatcagttac
     5221 ttcagcagca gtttggtctc ggcgtaaatg atgtaaagca cggttttacc gaggcggagc
     5281 tggccgcggt aatggctgca tttgataccc atccggaggc gggaaaataa ttttttgccg
     5341 cgaggatttg cgggcctgac aaagattaaa aagtaatggc ccattcggca tgaaacagaa
     5401 tgaccgcctg gccggagatg gtgacgtttt ccggctggtt atcgcgaatg gtgacggtaa
     5461 catcaacagt accctctttg cctaaagcgc gcccctgatg gccttgaatc tgtagcgttt
     5521 taccgtcatg cgccatcagg ccatgatgga cgagccatgc ccccatcggg ccattggcgt
     5581 ttcccgttac cggatcttcc acaattccta tcgccgggga aaacattcgc ccatcggttt
     5641 cgttttttcc cggacgaatc tggaaaggaa aaaagccgtt acagccaatt tgctggctga
     5701 ttgccgtcag ggctgccaga ttcggcgaaa gggcatcaat atcaacgtct ggtttgagca
     5761 ggatcatcac ttttgcatgt cctgttgaag ccacctgaat tggcgctccc ggcacgatat
     5821 catcttcagt caggttcagt gcggtgatga tggcagcccg aatctctccg actagcggtg
     5881 gttcaaaaga gggctgacct tgttccagcg tgatgcgata gtcgttgtgt tcggcatgaa
     5941 tttcaacgcg atgacggccc gctaacgagg tttgccagac ggtggtgttt cccaacccca
     6001 gtaccgttgc ccgaacataa tgcgcggcca cagtggcatg accacagatg gggacttcta
     6061 ctgtcggtgt aaagtagcgt atgcgcacat cactctcttc gctttttagc aaaaaggcgg
     6121 tttccgagtg acgaagttca cgggcaatca gctgcatctg cgcgtcgctt agcgtatccg
     6181 catgtaagac aacgccagca gagttgccgc gaaagggttc gctggtgaag gcgtcaacat
     6241 ggtaaatctg cggtttcatt gatgttctcc tttgactgaa gaatcatcat agcctgtgcg
     6301 ttgccgaatg acgacgccca ggcgtttttc tttgcccggt aagcgtaccc ccggtcaaag
     6361 agaattagcg gcgggtacga acaatctggt agcgacgggt gaaatactcg aacggcgcgc
     6421 tccagacatg aaccagacgg gtgaacggga agagcaggaa aaatcccgcg attcctgaac
     6481 aatctgcttg gtgacactgt cacttgtaag cgtactgccc gccagcgtca gcagggcgtc
     6541 aaatagttga taccacggcg ctcctcgctg tttcagacga ccgcccagta gcgccagaat
     6601 aggggcaata ttctgtaatc cctcgcgcgc ttccgcttcc ggcaacacgc ttaagtactc
     6661 cagatagagc ggcaggtgat ccggcagttc gcggcagttg aggtgcaggc ccacggtttc
     6721 atactggctt aacaaatcga ccatcgcctg gccgcgatcg cgggactccg catgaacatg
     6781 ctcgaataac agcaatgaag tggcgcgccc gcggtcaaac acttcgcacc attctgcttg
     6841 tttatccagt aacggcgcat aaagcagctc gcgagtgaag ttggccagca ttggcgcatc
     6901 gtgttggatt agggcaagcg cttcatcccg acattcccac aactcgtcgt ccggatactc
     6961 catcaacagg ccaatcgctt tgaggatttg cattattccc cctccgcttt atcacgtact
     7021 tcggtgatat tgatggcatc aatacggcta ctgttgaaca ggttgaattt ggtatccgag
     7081 ccgtgacaac cgtcgccaaa agtaaagccg cagccgttgc gctccggaaa ggcatcgcgc
     7141 gccatttccc ggtggctggt gggaatgaca aaacgatctt cataattggc aatcgccagg
     7201 tagcgataca tctcttcaac ctgttgtacg ctcagaccga cttcgtcaat ggcgcgggta
     7261 tccgtcacgc cttcaaccgt ctgcgagcgc atgtagtggc gcatcgccat catccgcttt
     7321 agcgcccgaa tgaccgggcc ggtatcgccc gcgctgagca tattggccag gtactggacc
     7381 ggaatacgca gcgtctccac cgccggcaga atattgccat tgtgcggcaa cccgcccgcg
     7441 tcggcgtatg actggatggg cgatagcggc ggtacgtacc agaccatcgg cagggtacgg
     7501 tattccgggt gcagcggaag cgccagcttc cagtccatcg ccattttgta caccggcgac
     7561 cgttgggcgg cgtcgatgac gttttgcggg atgccctgtt taagcgcctc ttcgatgacc
     7621 gccggatcgt gcggattgag aaacacatcg cactgacgtt catacaaatc tgtctcgtgt
     7681 tcggtactgg ccgcttcttc aatcctgtcg gcgtcgtaga gcagaacgcc aagataacgg
     7741 atgcgcccga cgcaggtttc cgagcaaacg gtcggctggc cggattcaat acgcggatag
     7801 caaaatatgc atttctcaga cttgccgctc ttccagttaa agtagatttt tttgtatggg
     7861 cagccgctga tacacaaacg ccagccccgg catttatcct ggtcgattag cacgatgccg
     7921 tcttcttcac gcttataaat agcgccactt gggcaggtgg caacacaact ggggttcagg
     7981 cagtgttcgc acaggcgcgg caggtacatc atgaaggtgt tttcgaactg accgtacatc
     8041 tccttttgta tgttgtcgaa gttgcggtcg cgggcgcgtt tttcaaactc gccgccgagc
     8101 agctcttccc agtttggccc ccagatcacc ttgtccatcc gttttccgtc gatcagtgaa
     8161 cgcggacggg cagtgggctg atgcttactc tccggcgctg tatgtaaatg ctgataatcg
     8221 aaggtaaagg gttcatagta atcatcgatt tgcggaatca ccgggttggc gaaaattttg
     8281 ctaattaccc ccattttgcc gcccagacgg ggccttatct tgccattaac atcacgaacc
     8341 caaccgcctt gccactcctg ctggtcttcc caatttttgg gatagccaat acccggttta
     8401 gtttcgacgt tattgaacca tgcgtattcc atcccttcac gtccggtcca gacgttttta
     8461 caggtgacgg agcaggtgtg acagccaata catttatcga gattcagtac catcccaacc
     8521 tgtgagcgta ttttcatttt ttcgcctcct gtacctgatc ccggccctca tcatccagcc
     8581 agttaatgtt tttcatcttc ctgatcatga tgaattcatc gcgattcgaa cccacggttc
     8641 cgtaatagtt gaagccgtaa gccagttgcg catagccgcc gatcatatgc gtcggttttg
     8701 gacagacccg ggtcacggag ttatggatcc cgccgcgcat cccggtgact tccgaacccg
     8761 gaatgttcat aatccgctcc tgggcgtggt acatcatggt catacccggc gggacgcgct
     8821 ggctgaccac cgcgcgagcg gtaagggcgc cattagcgtt gaaggcttca atccagtcgt
     8881 tatcttcaat acccagttca cgggcatcgg cttcgctgat ccagacaatc ggcccgccgc
     8941 gcgacaaggt cagcatcagc aggttttcgc tgtaggtgga gtgaattccc catttctggt
     9001 gcggcgtcag gaagttaagc gctttttccg ggaaaccgtt gggcggaatt tctcgcattt
     9061 cgctgacgct gcgggtatca atcggcgggc gatatgccac caggctttcg ccaaaagcgc
     9121 gcatccacgc atgatcctga tagagttgtt gccgccccga caacgtgcgc cacgggatca
     9181 gttcatgtac gttggtatac ccggcgttat aagagacatg ctcgctttcc agtcctgacc
     9241 aggtcgggct ggagataatt ttgcgcggtt gcgcctggat atcacgaaag cgaattttct
     9301 catcttcttt attgatggcc agatgggtgt gctcgcgccc ggtcatctcg cccaacgcct
     9361 gccaggcttt caccgccacc tggccgttag tttccggcgc taaggcaaga atcacttccg
     9421 aggcatccag cgcggtgtcg atgcgcggac gtcctttcgc cgggccatcg tgtttggtgt
     9481 aattgagctt accgaggaaa tcgacttcat cttgcgtatt ccaggcaata cccttaccgc
     9541 cgttgcctaa tttatccagc aggggaccca gcgaggtaaa acgttcatag gtggccggat
     9601 aatcgcgttc aaccacgacg atattggggg cggttttgcc cggaataagt tcgcactcgc
     9661 ctttacgcca gtcgagaata tcaaatggct gcgccagttc cgccggggaa tcatgctgga
     9721 gcgggtgtaa caccacatcg gtttcctgtc cgaggtgtcc gacacacact tcagaaaagg
     9781 cgctggcgat gcctttgtag atctcccagt cgcttttgga ttcccaggca ggatcgaccg
     9841 cggcggaaag ggggtggata aacggatgca tatccgaggt attcatatcg tctttttcat
     9901 accaggtggc ggtcggcaag acgatatcgg aaaacagaca ggtactggac atacggaaat
     9961 caagcgtgac caacagatcg agcttgccct caatcgcggc ggactgccat tccacctctt
    10021 caggcttaat tccttcgctg gaacccagcg cttcgccctg gataccgctg tcggtgccca
    10081 gcagatattt gagcatgtac tcatgacctt tcccggagga gccgagcagg ttagagcgcc
    10141 agacaaataa atttcgcggg tgattatgac cactgtcagg ccgttcgcag gcaaaacgga
    10201 tagcgcctga tttcaacacc tgcatggtat aatccgccgc agacagcccg gctttatcgg
    10261 cgctcgcttt cacgctgagc gggttaagat taagctgcgg cgccgagggt agccagccca
    10321 tacgttccgc gcgcacgttg aaatcgatca gatgtccggt aaatttagtc ggatcggcca
    10381 acggcgacag caactcttgc gcagtcagtt tttcatagcg ccactggctg gcatggttgt
    10441 agaaaaacga ggtactgttc atctgacgcg gcgggcgatt ccagtccagc gcgaaggcca
    10501 gcggcagcca gccggtttgc ggccgcagct tctcctggcc gacatagtgc gcccagccgc
    10561 caccggtttg tccaacacag ccgcagaaca ccagcatgtt aatcatccca cggtaattca
    10621 tatccatgtg ataccagtga ttcactcccg cgccgaggat gatcatcgaa cgaccgtgag
    10681 ttttatgggc ggtctcggca aattcacgcg caatagtttc gatatgtcga cgcggcacgc
    10741 cggtaatctg ttcgccccag gccggcgtgt aggctttgac atcgttataa ttattggcgc
    10801 tatggccgtc atccagacca cgatccagcc cataattagc cagcaccaga tcgtaaacgc
    10861 tgacgaccat ccgctcgcta ccgtccgcca gagccaggcg tttcaccggt aactgacgta
    10921 ccagcaccgg ttcctgccgc acgctgcgaa aatgtgggtt ttcgttgtcg ccaaaatagg
    10981 ggaaggcgac acccgccacg tcatcatgct gaccgagtaa agagagcgac agttcagttt
    11041 cgacgcccgc cgccaccggt tccaggttcc attttccctt ttcgccccag cgaaaaccga
    11101 tagaaccgtt gggcgcgacc agttcgcccg tactgttgag cgcgacggtt ttccattccg
    11161 gattattggc ttctcccagt ccatccacca gatccgacgc gcgcatcata cgccccggta
    11221 cataactgcc gtctgcgcgc tcatccaaca ggactaacat cggcatgtcg gtataacggc
    11281 ggcaatagtt aaggaaatag tcgctgggat tatcgagatg aaactctttc aaaatgacgt
    11341 gacccatggc catcgccagc gcgctgtcgg taccttgctt tggcgccagc cactgatcgc
    11401 acagtttagc gacttcggaa tagtccgggg tgatggcaat tgtcttggtg cctttgtagc
    11461 gcacttcggt aaagaagtgg gcgtccgggg tacgcgtttg cggcacgtta gagccccagg
    11521 caataatgta ggctgagtta taccagtcgg cggactccgg cacgtcagtc tgctcgcccc
    11581 aggtcattgg cgacgcgggc ggaagatcgc aataccagtc atagaagctc agacaagtac
    11641 cgccaagcaa tgacagataa cgtgttccgg cggcgtaaga aaccatcgac atcgccggaa
    11701 taggtgaaaa acccgccaca cgatccgggc cataggtttt gattgtccag acgttagcgg
    11761 cggcaatgag ctgattcagc tctttccagt tcgaacgaat aaagccgcca tgtccgcgca
    11821 cctgtttgta actttggcat ttttgcgggt cgttcattat agattcccat gccagcaccg
    11881 gatcgctgtg gcgggaaagg gcctctcgcc acagttctat cagccgctta cgcaccagag
    11941 ggtatttcaa acgattggcg ctatagagat accaggagta gctggcgccg cgcggttcat
    12001 ggttcggtaa atcgggacgt gtgcgcgggt agtcggtttg ctgggtttcc cacgtcacca
    12061 gaccattttt gacataaatt ttccaactac aggagcccgt gcagttgacg ccgtgggttg
    12121 agcgcacgat cttatcaaac tgccagcgct ggcgataact gtcttcccag tcgcggttgg
    12181 tatgcatcat ctgaccatgg ccgtcagcaa aggtatcgcc tttttgttta aagtaacgaa
    12241 agcgatccaa cagtttactc atgacatttc tcctgcttcg ataaattttc cgccatcctg
    12301 tcgatttggc gttaaaccat taccggatgg ccgtcctaca agtgcgtatg ttgttattgt
    12361 tgtttaggct taagacgccc gtagaccagc caggtcagca ggacgcaagc gatgtaaaac
    12421 agcaaaaaga ttttcatggc gcccaccggc gagccggtca aggccaaaga ggtgccaaac
    12481 gcttttggaa taaagaagcc gcccacagcg ccaatagcgg agataaaacc gagcgcggcg
    12541 gcggtatccg tcaccgcttc gcgctgcgcc tgctcatcgc tcccgccgcg cagtttgacg
    12601 ttgtagagcg tgatctgccg gaagatcacc gcaatcatct ggaaggtaga accgctgccg
    12661 agacccgctg tcaaaaacag gcccataaaa acaagataga acgcgctaaa gctgcctgcg
    12721 ccggagcctg gcagcgtgag gaatagcagg gcggtaaaca gcgccataaa gataaaatta
    12781 atgagcgtga cgcgaacgcc gccgaattta tcggagatca cgccgcctgc cgatcgcgcc
    12841 agcgcgccga taaaggggcc aaagaacgcc agttgcagaa tgtttacgtc gggaaattgc
    12901 gttttggcga gcatggcgaa acctgcggaa aagccgatga atgacccgaa tgtcgccagg
    12961 tacagcaggc taagcagcca caggtgcaga cgttttagca ccggcaattg cgaggcgaca
    13021 gacgcttttg aactgccgat atcgttcata ccaaaccagg cggcaagcgt cgcaacagcc
    13081 agtaacggca cccagatcca ggcggcgtta gtgagggcga gcagggagcc atcaggttgc
    13141 ggcacgcccc ggacgcctaa aaaagtaaat atcggcaaaa aaataaccag cggcgcaatc
    13201 aactgcatca cactgacgcc aagatttccc agtccgtcgt taatacccaa cgcgctacct
    13261 tgtctggctt ttggaaagaa aaaactgatg ttgcccatac tggacgcgaa atttgccccc
    13321 gcaaaaccgc acaacagagc gatgagtata aataccccga aaggggtggc aggattttgc
    13381 acggcgaatc ccagccaggc gcaaggaata atcaatatta cggtacttaa tacggtccat
    13441 ttacgaccac caaacagtgg taccataaag gagtagggaa cgcgtaatat tgcgccggaa
    13501 agagaaggta atgcggttaa taaaaagagt tggtcggtcg taaaatcaaa tccaatttta
    13561 ttgaggttga cggcaacagc gctaaacaac atccagacgc aaaatgcaag gagcaaacaa
    13621 cttactgaaa tccataagtt tcttctggcg atgcctttcc ctttattctc ccagaaggct
    13681 ggattttcgg gtcgccagtc actcaagaga taacggttat aattctcgtt ttgtcgtgtc
    13741 attttacccc tcacatgcgc atatcatttg aaaaaaaaca caaaaa
//
LOCUS       DAJVBX010000124        13478 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.124, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000124 DAJVBX010000000
VERSION     DAJVBX010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 13478)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13478)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13478
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.124"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            231..1277
                     /gene="ansB"
                     /locus_tag="OPV72_003000"
     CDS             231..1277
                     /gene="ansB"
                     /locus_tag="OPV72_003000"
                     /EC_number="3.5.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-asparaginase 2"
                     /protein_id="HCR9915236.1"
                     /translation="MEFFRKTALAALVMGFSGAAFALPNITILATGGTIAGGGDSATK
                     SNYTAGKVGVENLVDAVPQLKDIAVVKGEQVVNIGSQDMNDEVWLTLAKKINTECDST
                     DGFVITHGTDTMEETAYFLDLTVKCNKPVVLVGAMRPSTSMSADGPFNLYNAVVTAAD
                     KQSANRGVLVVMNDTVMDGRDVTKTNTTDVATFKAVNYGPLGYIHNGKIDYQRTPERK
                     HTTSTPFDVSKLTALPKVGIVYNYANASDLPAKALVDAGYDGIVSAGVGNGNLYKTVF
                     DTLATAAHNGTVVVRSSRVPTGATTQDAEVDDAKYGFVASGTLNPQKARVLLQLALTQ
                     TKDPKQIQTMFNQY"
     gene            1410..2417
                     /locus_tag="OPV72_003001"
     CDS             1410..2417
                     /locus_tag="OPV72_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1202 domain-containing protein"
                     /protein_id="HCR9915237.1"
                     /translation="MVRQWIAGAALFALISGYSWAEVAQPSDNILKEQFSKQYHGILK
                     LDSITLKNLDSTGNQATWSAEGDISSREDMYTGVGMAADYYFVEKTWTKDRPVKFSAM
                     LTSKGTPASGWTVSYYSLQMAASDQGRAIDDIKTNDKYLIVNSDDFNYRFGNIEASWR
                     AQKASIPGLEEQLSALDKKIAVAKKEADAYWGKGADGKPLTRAEAFKKTLKERDDYVK
                     ANDSSVYAEKYEKEVYQPALDACRKQSEPCNEAAIQQKRDLDIHEQRRQVFLKSEELR
                     RKAQNDWITLEKGQYPLNIAVQKLQMQQSDIRMKIMDINDGYERWKKDTDDLRRKGVI
                     K"
     gene            complement(2508..3644)
                     /gene="hemW"
                     /locus_tag="OPV72_003002"
     CDS             complement(2508..3644)
                     /gene="hemW"
                     /locus_tag="OPV72_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HCR9915238.1"
                     /translation="MAKLPPLSLYIHIPWCVQKCPYCDFNSHALKGEVPHDDYVQHLL
                     SDLDADVAWAQGREVKTIFIGGGTPSLLSGPAMQTLLDGVRARLNLAADAEITMEANP
                     GTVEADRFIDYQRAGVNRISIGVQSFSEPKLKRLGRIHGPQEAMRAARLANGLGLRSF
                     NLDLMHGLPDQTLEEALNDLRQAIALNPPHLSWYQLTIEPNTLFGSRPPVLPDDDALW
                     DIFEQGHQLLTAAGYQQYETSAYAKPGYQCQHNLNYWRFGDYLGIGCGAHGKVTFPDG
                     RILRTTKTRHPRGYMQGRYLESQRDVSDDDKPFEFFMNRFRLLERAPRAEFVDYTGLT
                     EAVIRQPIDEAIAQGYLTECEQYWQITRHGKLFLNSLLELFLAE"
     gene            complement(3637..4230)
                     /locus_tag="OPV72_003003"
     CDS             complement(3637..4230)
                     /locus_tag="OPV72_003003"
                     /EC_number="3.6.1.66"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XTP/dITP diphosphatase"
                     /protein_id="HCR9915239.1"
                     /translation="MQKVVLATGNAGKVRELASLLSDFGLDVVAQTKLGVDSAEETGL
                     TFIENAILKARHAAKMTGLPAIADDSGLAVDVLGGAPGIYSARYSGENATDQQNLEKL
                     LHTLRDVPDDKRQARFHCVLVYLRHAEDPTPIVCHGSWPGVITRQAAGNGGFGYDPIF
                     FVPSEGKTAAELTREEKSAISHRGQALKLLLDALRNG"
     gene            complement(4238..4528)
                     /locus_tag="OPV72_003004"
     CDS             complement(4238..4528)
                     /locus_tag="OPV72_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggU family protein"
                     /protein_id="HCR9915240.1"
                     /translation="MSAVTRCEDGLVLRLYIQPKASRDSIVGLHGDEVKVAITAPPVD
                     GQANSHLTKFLGKQFRVAKSQIVIEKGELGRHKQVKIIHPQQIPPEIAALTE"
     gene            complement(4525..5091)
                     /locus_tag="OPV72_003005"
     CDS             complement(4525..5091)
                     /locus_tag="OPV72_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HCR9915241.1"
                     /translation="MNTLTFLLSTVIELYTMVLLLRVWMQWARCDFYNPFSQFVVKIT
                     QPIIGPLRRIIPPMGPIDSASLLVAFILSVIKAIVLFKVITFQAIIWIAAVLILLKTI
                     GLLIFWVLLVMAIMSWVSQGRSPIEYVLIQLAEPLLSPIRRILPAMGGIDFSPMVLVL
                     LLYVVNMGIAEVLQATGNMLLPGLWMAL"
     gene            complement(5110..5814)
                     /locus_tag="OPV72_003006"
     CDS             complement(5110..5814)
                     /locus_tag="OPV72_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HCR9915242.1"
                     /translation="MNDIAHNLAHIRDKISAAATRCGRSSEEVTLLAVSKTKPASDIA
                     EAIAAGQRAFGENYVQEGVEKIRHFQEAKVEGLHWHFIGPLQSNKSRLVAEHFDWCHT
                     IDRLRIASRLSEQRPDNLPALNVLIQINISDENSKSGIPLAELDELAAAVATLPRLRL
                     RGLMAIPAPESDYVRQFEVARQMAVAFAGLKARYPDVDTLSLGMSDDMEAAIAAGSTM
                     VRIGTAIFGARDYTKN"
     gene            5832..6812
                     /locus_tag="OPV72_003007"
     CDS             5832..6812
                     /locus_tag="OPV72_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus twitching motility protein PilT"
                     /protein_id="HCR9915243.1"
                     /translation="MNMEEIVTLSVKHNVSDLHLCNAWPARWRKQGRMETAPFTAPDV
                     DRLLLDWLNDAQQYQWRTHGQLDFAVSLSGTRRLRASAFTHQQGTSLAIRLLPERCPD
                     LAEIQTPPIVPALLASENGLILVTGATGCGKSTTLAAMVGHLNQHADKHILTLEDPIE
                     YRYTSKRCLIQQREIGQHCATFAAGLRAALREDPDVILLGELRDSETIRLALTAAETG
                     HLVLATLHTRGAAQAVERLVDSFPAQEKEPVRSQLAGSLRAVLSQKLEVDRQDGRVAL
                     FELLINTPATGNLIREGKLHQLAHVIQTGQQQGMMTFAQSAQWRQAQGRL"
     gene            6942..7628
                     /locus_tag="OPV72_003008"
     CDS             6942..7628
                     /locus_tag="OPV72_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HCR9915244.1"
                     /translation="MSSQPNQSLIDGIRCLQYLVSSDRAIGCRELARLMDINTTRVNR
                     LLMTMASIGLTMQDEHRRYLPGPGIHALAAQAIRGSALFSHALPILERHAPRDIVVAL
                     GVLWEDQIIYIYHSTPGAQGSQALAGFRMCLAWQSVPGVALLAAESDEALMQRFSPEQ
                     WRNLAPHVAQQRQRGYVLWHHADGEVSMAQPLDKHAAALAFAGMWRIDEAEAAARLQA
                     LKALNQLIAQ"
     gene            complement(7675..8091)
                     /gene="ruvX"
                     /locus_tag="OPV72_003009"
     CDS             complement(7675..8091)
                     /gene="ruvX"
                     /locus_tag="OPV72_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HCR9915245.1"
                     /translation="MSDTLLAFDFGTKSIGVAIGQRITGTARPLPAIKAQDGTPDWTL
                     IERLLKEWQPDEIIVGLPLNMDGTEQPLTARARKFANRIHGRFGVTVTLHDERLSTVE
                     ARSGLFERGGYRALNKGKVDSASAVIILESYFEQGY"
     gene            complement(8091..8654)
                     /locus_tag="OPV72_003010"
     CDS             complement(8091..8654)
                     /locus_tag="OPV72_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgE/AlgH family protein"
                     /protein_id="HCR9915246.1"
                     /translation="MNLQHHFLIAMPALQDPIFRRSVVYICEHNQDGAMGIIINKPLE
                     NLQIEGILEKLKITPEPRDSAIRLDKAVMLGGPLAEDRGFILHTPPSRFASSIRISDN
                     TVITTSRDVLETLGTQQQPSDVLVALGYASWDKGQLEQELLDNAWLTAPADLNILFKT
                     PIAERWREAAKLIGIDILTMPGVAGHA"
     gene            complement(8870..9817)
                     /gene="gshB"
                     /locus_tag="OPV72_003011"
     CDS             complement(8870..9817)
                     /gene="gshB"
                     /locus_tag="OPV72_003011"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione synthase"
                     /protein_id="HCR9915247.1"
                     /translation="MIKLGIVMDPIAHINIKKDTSFAMLLEAQRRGYELHYMEMADLY
                     LINGEARACTRTLSVEQNYDKWYEFGSEQEIKLADLDVILMRKDPPFDTEFIYATYIL
                     ERAEEEGTLIVNKPQSLRDCNEKLYTAWFADLTPETLVTRNKAQLKAFWEKHGDIIMK
                     PLDGMGGASIFRVKEGDPNIGVIAETLTELGNRYCMAQNYLPAIKDGDKRVLVVDGEP
                     VPYCLARIPQGGETRGNLAAGGRGEPRPLSESDWEIARRVGPTLKAKGLIFVGLDIIG
                     DRLTEINVTSPTCVREIEAEYPISITGMLMDAIEARLAK"
     gene            complement(9837..10568)
                     /gene="rsmE"
                     /locus_tag="OPV72_003012"
     CDS             complement(9837..10568)
                     /gene="rsmE"
                     /locus_tag="OPV72_003012"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013319572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HCR9915248.1"
                     /translation="MRIPRIYHPELLTSGTQISLCEDAANHIGRVLRMGAGQALQLFD
                     GSNQVFDAEIISASKKSVEVQVMKGEIDDRESPLHIHLGQVMSRGEKMEFTIQKSIEL
                     GVSLITPLFSERCGVKLDNERLNKKRQQWQKIAIAACEQCGRNRVPEIRPPMALEAWC
                     AEQDSGLRLNLHPRAHASINTLPLPVERVRLLIGPEGGLSADEIAMTARYQFTDILLG
                     PRVLRTETTALTAITALQVRFGDLG"
     gene            complement(10645..11352)
                     /gene="endA"
                     /locus_tag="OPV72_003013"
     CDS             complement(10645..11352)
                     /gene="endA"
                     /locus_tag="OPV72_003013"
                     /EC_number="3.1.21.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease I"
                     /protein_id="HCR9915249.1"
                     /translation="MYRNFSFAAALLAAAFSGQALADGINNFSQAKAASVKVNADAPG
                     SFYCGCQIRWQGKKGVVDLESCGYKVRKNENRARRIEWEHVVPAWQFGHQRQCWQDGG
                     RKNCAKDPVYCKMESDMHNLQPAIGEVNGDRGNFMYSQWNGGEGQYGQCAMKVDFKAK
                     LAEPPARARGAIARTYFYMRDQYQLKLSRQQTQLFNVWDKQYPVTAWECERDARIAKV
                     QGNHNPYVQRACQARKS"
     gene            complement(11448..11945)
                     /locus_tag="OPV72_003014"
     CDS             complement(11448..11945)
                     /locus_tag="OPV72_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family zinc-dependent metalloprotease"
                     /protein_id="HCR9915250.1"
                     /translation="MKTPRLPIAIQQAVMRRLRENLAQANLKLDRHYPEPKLVYTQRG
                     TSAGTAWLESYEIRLNPVLLLENIDTFIAEVVPHELAHLLVWKHFGRKAPHGKEWKWM
                     MESVLGVPARRTHQFALQSVRRNTFPYHCQCQQHQLTVRRHNRVVRGEAVYRCVHCGE
                     PLVAG"
     gene            complement(12024..13418)
                     /gene="galP"
                     /locus_tag="OPV72_003015"
     CDS             complement(12024..13418)
                     /gene="galP"
                     /locus_tag="OPV72_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/proton symporter"
                     /protein_id="HCR9915251.1"
                     /translation="MPDNKKQGRSNKAMTFFVCFLAALAGLLFGLDIGVIAGALPFIT
                     DEFQITAHTQEWVVSSMMFGAAVGAVGSGWLSFKLGRKKSLMIGAILFVAGSLFSAAA
                     PNVEVLIISRVLLGLAVGVASYTAPLYLSEIAPEKIRGSMISMYQLMITIGILGAYLS
                     DTAFSYSGAWRWMLGVIIIPAILLLIGVFFLPDSPRWFAAKRRFHDAERVLLRLRDTS
                     AEAKRELDEIRESLQVKQSGWALFKENSNFRRAVFLGILLQVMQQFTGMNVIMYYAPK
                     IFELAGYTNTTEQMWGTVIVGLTNVLATFIAIGLVDRWGRKPTLTLGFLVMAIGMGIL
                     GTMMHIGIHSPSAQYFAIAMLLMFIIGFAMSAGPLIWVLCSEIQPLKGRDFGITCSTA
                     TNWIANMIVGATFLTMLNNLGNANTFWVYAGLNVLFILLTLWLVPETKHVSLEHIERN
                     LMKGRKLREIGAHD"
BASE COUNT         3176 a         3567 c         3694 g         3041 t
ORIGIN      
        1 cttaaagcta aaagctttcc ggaaccccca gcctagctgg gggttttcca tagacaacaa
       61 tggcgcagat cgtatctgcg cctttttatt ctgttttttc ctgcattttg ttatccatct
      121 ctaaaaaata ctctctgtcg gatatatatc gctggttaat cgtatggcgt cacattattc
      181 gtctgcaata tagggataat gcgaccagtt gacataactg gagatataac atggagtttt
      241 tcaggaaaac ggcattagct gctctggtaa tgggtttcag cggcgcagcg ttcgctttac
      301 cgaatatcac catcttagcg accggcggaa cgatcgctgg cggcggtgat tcagcaacaa
      361 aatcaaatta tacggcaggt aaagtcggcg tcgaaaatct ggtggatgcc gttcctcaat
      421 tgaaggacat tgcggtagtg aaaggcgagc aggtcgttaa cattggctcg caggatatga
      481 acgatgaagt ctggctcacg ctggcgaaaa aaatcaatac cgagtgcgac agcaccgacg
      541 gtttcgtgat cacccacggt actgatacga tggaagagac cgcttatttc ctcgatctga
      601 ccgtgaaatg caataaaccg gtggtactgg tcggcgcgat gcgtccttcc acgtcaatga
      661 gcgcagatgg cccgttcaac ctctataatg cggtagtaac agcggctgat aaacagtctg
      721 ccaaccgcgg cgtgctggtg gtaatgaatg ataccgtcat ggacggacgc gacgtcacta
      781 agaccaatac gactgacgtg gcgacgttta aagcggttaa ctacggcccg ctgggttata
      841 tccacaacgg taaaattgac taccagcgta cgccagagcg taaacatacc acctccaccc
      901 cgttcgacgt gtcgaagctg accgcgttgc cgaaagtcgg tatcgtttat aactatgcga
      961 atgcgtccga tctgccggca aaagcgctgg tagacgcggg ttatgacggg atcgtgagcg
     1021 caggcgtggg taacggcaac ctgtataaaa cggtctttga taccctagcg accgccgcgc
     1081 acaacggtac ggtagtggtg cgttcttcac gtgtgccgac tggcgcaacc acgcaggatg
     1141 cggaagttga cgatgcaaaa tacggctttg tcgcttccgg cacgctgaac ccgcaaaaag
     1201 cgcgtgtctt actgcaactg gcgttaaccc agactaaaga tccaaaacag atccagacga
     1261 tgttcaatca gtattaaaga taatgccccg gtcggaaggc cggggccatc tttggaagac
     1321 ctctcgcaca accaacacta ttatcttgct aattatcatc ctggttatga taattgtggg
     1381 cgtcatgtct ctggacggga ggtccacaag tggttcgaca atggattgct ggcgcagcgc
     1441 tgtttgccct gatttcaggc tatagttggg cagaggttgc tcaaccctcc gataacatct
     1501 taaaagaaca gtttagtaag cagtaccacg gcatacttaa actggattcc attaccttaa
     1561 aaaatcttga ttcgacgggc aatcaggcca cctggtctgc cgaaggggat atttcttccc
     1621 gtgaagatat gtataccggc gttggtatgg cggcggatta ttattttgtt gaaaaaacct
     1681 ggaccaaaga tcgtcccgtt aaattttctg ccatgttaac cagcaaaggg acgccagcct
     1741 ctggctggac ggtgagctat tactcattac aaatggcagc cagcgatcag ggccgggcta
     1801 ttgacgacat taaaacgaat gataaatacc tgatcgtcaa cagtgatgac tttaactatc
     1861 ggtttggcaa cattgaagcc tcctggcgtg cgcagaaagc gtcgatcccc ggtcttgaag
     1921 aacaactctc tgccctggat aagaaaatag cggtagctaa aaaagaagcg gacgcatatt
     1981 ggggaaaagg cgctgatggg aaaccgttga cccgcgccga ggcgtttaaa aagacgttaa
     2041 aagagcgcga tgattatgta aaagccaacg atagcagcgt atatgccgag aaatacgaaa
     2101 aagaggtcta tcaaccagca ttagacgcgt gtcgtaagca gagtgagccg tgcaatgaag
     2161 cggctattca gcagaaaaga gatttagaca tacacgagca acggcggcag gtatttttga
     2221 aatcagaaga gctgcgtcga aaagcgcaga atgactggat aacgttagag aaagggcaat
     2281 atccgctgaa tatagcggta cagaaacttc agatgcaaca gagtgatatc cgcatgaaaa
     2341 tcatggatat taatgacggt tacgagcgct ggaaaaaaga tacggacgat ttgcgtcgta
     2401 aaggcgttat taaataatgc gcttgctggt ggcgcattaa ccgccacagg tcggtaagcg
     2461 tcgcgccatc aggtatttta cccgctggcg cgacaggctt atccttgtta ttccgcgaga
     2521 aacaactcaa gaagagagtt taaaaacagt ttaccgtgac gggtaatctg ccagtattgc
     2581 tcgcattctg tcaggtagcc ctgggcaata gcctcgtcga ttggctgacg aataaccgct
     2641 tccgtaagcc cggtgtagtc gacaaattcg gcgcgaggcg cgcgctccag caaccgaaaa
     2701 cggttcataa agaactcaaa gggtttatcg tcatcactca cgtcacgctg gctttccagg
     2761 taacgtccct gcatataacc gcgtgggtga cgggttttgg tggtgcgcaa gatcctgccg
     2821 tccgggaagg tgactttacc gtgggcgccg cagccaatac ccagatagtc gccaaagcgc
     2881 cagtagttca gattatgctg gcactgataa ccgggtttgg cataggccga cgtttcgtat
     2941 tgctgatagc ccgcggcggt taataactgg tggccctgct caaagatatc ccacagcgcg
     3001 tcatcgtccg gtaaaaccgg cggacgcgaa ccgaacaaag tgttgggttc aatcgtcaat
     3061 tgataccatg agagatgcgg cggattaagc gcaatcgcct gtcgcaaatc attcagcgcc
     3121 tcttccagcg tttgatccgg caatccatgc atcaagtcga ggttaaagct gcgtagccca
     3181 agcccatttg ccagtcttgc tgcccgcatc gcctcttgtg gaccgtgaat acggccaaga
     3241 cgtttcagct taggctcact aaagctctgc acgccaatgg agatccggtt tacgccggcg
     3301 cgctgatagt cgatgaagcg gtcggcttcg accgtgccgg ggttcgcttc catggtaatt
     3361 tccgcatccg ccgccagatt caggcgcgca cgcacgccgt ccagcagcgt ttgcatcgcc
     3421 ggcccggaaa gcaggcttgg cgtaccgccg ccaataaaaa tggtctttac ttcacgccct
     3481 tgcgcccaag cgacgtcggc atccagatcg cttaacagat gctggacgta gtcgtcatgc
     3541 ggcacctcgc ccttcaacgc atgggaattg aagtcgcaat atggacattt ttgtacacac
     3601 cagggaatat gaatataaag actgagcggc ggtagtttag ccattgcgta acgcatccag
     3661 cagcagcttg agcgcttgtc cacggtggga aatcgcgctt ttttcttcac gggtcagttc
     3721 tgcggcggtt ttgccttcag acggtacgaa gaaaatggga tcatagccaa atccgccatt
     3781 tccggccgcc tggcgagtaa tgacgccagg ccagctaccg tgacagacta tcggtgtggg
     3841 atcttcggca tgacgcaaat aaaccagtac acaatggaat cgcgcctggc gtttgtcgtc
     3901 cggaacatct cgtagagtat gcagcagttt ttccagattt tgctgatctg tcgcgttttc
     3961 gccagaatag cgcgcggaat agatacccgg cgcgccgcct aaaacgtcaa cggccagacc
     4021 ggagtcatcg gcaatggcgg gcagaccggt cattttagcg gcatggcgcg ctttgagaat
     4081 cgcgttttca ataaacgtca ggccggtttc ttccgcagag tcaacgccca gtttcgtttg
     4141 cgctaccaca tcaagcccaa aatcgcttaa cagcgacgcg agctcgcgca ctttaccggc
     4201 gttgccggtt gcgagaacaa ctttttgcat ggaataccta ctcagttaac gccgcaattt
     4261 ccggcgggat ctgttgcggg tgaataattt ttacctgttt gtgacggccc agctcgcctt
     4321 tttcgatgac gatctgactt ttcgccacgc gaaactgttt accgagaaac ttggtcagat
     4381 ggctgtttgc ctgaccgtca accggcgggg cggtaatggc gactttcacc tcgtcgccat
     4441 gtaaacccac aatactgtcg cggctggctt tcggctgaat ataaagccgt aacaccagac
     4501 cgtcttcgca gcgagtcaca gcactcatag cgccatccac agccccggca gcaacatgtt
     4561 gcctgtcgct tgtaagactt cagcgatccc catattaacg acatacagca gcagcaccag
     4621 aaccatcggc gagaagtcga tgccgcccat cgcaggcagt atacggcgaa tcgggctgag
     4681 cagcggctcg gcaagctgaa tcaatacata ttcaatcggg ctacgaccct ggctcaccca
     4741 gctcatgata gccatgacca gcagcaccca gaagatcagc aggccgattg ttttaagtaa
     4801 gataagcacc gcggcaatcc agataatcgc ctgaaacgta attaccttaa acagcactat
     4861 cgccttaata acgctaagaa taaacgccac cagcagggaa gcgctgtcga tcggccccat
     4921 tggcgggata atacgacgca gcggtccgat gatgggctgc gtaattttca ccacgaactg
     4981 ggaaaaaggg ttgtaaaagt cacagcgggc ccactgcatc cacacgcgca ataatagcac
     5041 catggtatac agctcaatta ccgttgagag caggaaggtc aacgtattca tggcgttcct
     5101 cagttttcct taattttttg tgtaatcacg agcaccaaag atagcggtgc cgatgcgcac
     5161 cattgtgcta cctgccgcaa tcgcggcttc catatcgtcg ctcataccca gagataaggt
     5221 atcaacgtca gggtagcgcg ctttcagccc ggcaaatgct acagccattt gacgtgcgac
     5281 ttcaaactgc cttacataat ctgactctgg cgccgggatc gccatcagtc cgcgaagccg
     5341 cagacgcggc agtgtagcca ccgcagcggc cagctcatcc agttccgcca gcggaatgcc
     5401 tgatttgctg ttttcatcgc tgatattaat ttggatcaga acatttagcg ccggcagatt
     5461 atccgggcgc tgttcgctca gccgcgaggc gatacgcagg cgatcgatgg tatgacacca
     5521 gtcaaaatgc tcggccacca gccgactttt gttggactgt aaagggccaa taaagtgcca
     5581 gtgcaggcct tccactttcg cttcctgaaa gtggcggatt ttttccaccc cctcttgtac
     5641 ataattttca ccaaatgccc gttgtccggc ggcaatggct tctgcgatgt cgctcgcagg
     5701 tttggtttta ctcactgcaa gcaacgtaac ttcttctgaa gagcggccac aacgcgtcgc
     5761 cgcggcggag attttgtccc ggatgtgtgc caggttatgc gcgatatcgt tcattttccg
     5821 aggatgttta tatgaatatg gaagaaattg tgacgcttag tgtaaagcat aacgtctcgg
     5881 atctacacct gtgtaacgcc tggcctgcgc gatggcgcaa acaaggacgc atggagaccg
     5941 cgccttttac cgcgcctgat gtcgacaggc ttctgcttga ttggcttaat gacgcgcaac
     6001 aatatcagtg gcgaacgcac ggtcagcttg atttcgccgt ctcgctgtct ggcacgcggc
     6061 gcctgcgcgc cagtgcgttc acacatcaac agggaacgtc gctggcgata cggctattgc
     6121 ccgagcgttg tcctgatctg gcggaaatcc agacgccgcc gatagtaccc gcactgcttg
     6181 ccagcgagaa cggactgatt ctggtcactg gcgctactgg ctgcgggaaa tccactacgc
     6241 tggcggcgat ggtgggacat cttaatcaac atgccgataa acacatcctg acgctggaag
     6301 atcctattga gtaccgttac accagcaagc gttgcctgat acagcagcgg gaaatcggcc
     6361 agcattgcgc cacttttgcc gccgggctgc gcgcggcgtt acgtgaagat cccgatgtca
     6421 ttttactggg agagctgcgt gacagcgaga ccattcgcct ggcgctgacg gcggcggaaa
     6481 cggggcatct ggtactggca accctgcata ctcgcggcgc ggcgcaggcg gtggaaagat
     6541 tagtggatag ttttccggcg caggaaaaag aaccggtacg cagtcaactg gcgggtagtc
     6601 tgcgcgccgt actatcgcaa aaactggagg tcgacagaca ggatgggcgc gtggcgttgt
     6661 ttgaattact gattaatacg ccagccacag ggaatttgat ccgtgaaggc aaactccatc
     6721 agttggccca cgtgatacaa accgggcagc agcaggggat gatgacattc gcccagagcg
     6781 cgcaatggcg tcaggcgcag ggacggctgt agcgaagatg gcggcgtagg gaaggggaag
     6841 tgttgactgg cgcggtggat tgaacggcat acaggcttgt atcctggcga accggcgtta
     6901 aaatcgcagc tttgttaaaa ccacagcgaa gtcatttaac gatgtcatca caaccgaatc
     6961 aaagcctgat agatggcatt cgctgtctgc aatatctggt ctccagcgac cgtgctatcg
     7021 gatgtcgcga gcttgcccgg ctgatggata ttaataccac gcgcgttaat cgcctgttaa
     7081 tgacgatggc ctctattgga ctcacgatgc aggatgagca ccgacgctat ttacccgggc
     7141 caggcattca tgctttggcg gcgcaggcga ttcgcggttc agcgctgttc tcccatgcgt
     7201 tgcctatcct tgagcgacat gcgcccagag acatcgtggt ggcattaggc gtgctatggg
     7261 aagaccagat tatctatatt tatcactcta cgccgggggc gcagggaagt caggcgctgg
     7321 cggggtttcg catgtgcctg gcctggcagt cggtacctgg ggtggcgtta ctggcggcag
     7381 aaagcgatga ggcgctaatg cagcgtttta gtccggagca gtggcgtaat ctggcaccgc
     7441 atgtggcgca gcagcgccag cggggatacg tgctgtggca tcacgctgat ggtgaagttt
     7501 ctatggcgca accgctagac aagcacgccg cagcgctggc ctttgcggga atgtggcgga
     7561 ttgatgaggc ggaggcggct gcgcgtttac aggcgttgaa ggcattaaac cagcttattg
     7621 cccagtaagc ctggcaaccg tgaccgcgtt atccgcctgc tgacaaaaac ggctttaata
     7681 cccctgttca aaatagcttt cgaggataat cacggcggag gccgagtcca ctttgccttt
     7741 attcagcgcg cgatacccac ctcgttcaaa cagaccggag cgtgcttcaa cggtgctgag
     7801 tcgttcatcg tgtagcgtga cagttacccc gaagcgccca tgaatacggt tggcgaattt
     7861 acgggcgcgc gccgtcagcg gttgttcagt gccatccata ttgagcggta gcccgacaat
     7921 aatttcgtcc ggctgccact ctttcagcaa acgttcaatg agcgtccagt cgggcgtgcc
     7981 gtcctgtgct ttgattgccg gaagcggacg ggcggtgccg gtaatgcgtt gtcctattgc
     8041 aacgccgatg ctttttgtgc cgaagtcaaa ggccagtaag gtgtcgctca tcaggcgtgc
     8101 cccgcaacgc caggcatggt cagaatatca atgccaataa gttttgccgc ttcgcgccag
     8161 cgctcggcaa tgggcgtttt gaacaaaata ttgagatcgg cgggcgcggt aagccaggcg
     8221 ttatcaagca actcttgttc aagctggcct ttatcccagg aggcgtagcc cagcgcgacc
     8281 agcacatcgg aaggctgttg ttgggtacct aacgtttcca gcacatcgcg ggaggtggta
     8341 atcacggtat tgtctgagat acgaatgctg gaggcgaaac gtgacggcgg agtatggaga
     8401 ataaatccgc gatcttccgc cagcgggccg ccgagcatca cggctttatc aagacgaatt
     8461 gccgaatcgc gcggttccgg cgtaattttt agtttttcca gaatcccttc aatttgcaga
     8521 ttttccaaag gcttattaat aataatcccc atagcgccgt cctggttgtg ctcgcaaata
     8581 tacaccacgg aacggcggaa aatcgggtcc tggagcgcag gcatggcaat aagaaagtga
     8641 tgctgtaaat tcattgtcag aggttctgtt tcctggttca aaaaaacgac agcgttcagt
     8701 atgtggggaa agcggacggt tgtcactcat ataagccgtc ttttgccaaa ggacggcggc
     8761 cttatcgggc aatagactgc cggatggcga tgctgacgcg ccgccttatc cgaccggggc
     8821 ggcgtgattg ctcaggcccg gtaagcgcac gccaccgggc aataaacttt tacttcgcca
     8881 gacgcgcttc gatggcgtcc atcaacatcc cggtgataga gatcgggtat tccgcttcaa
     8941 tttcacgcac gcaggttggg ctggtcacgt taatttccgt taagcggtcg ccgataatat
     9001 ccagaccgac aaaaataagc cctttggctt taagcgttgg tccaacgcgg cgggcgattt
     9061 cccagtcgct ttcgctcaac ggacggggtt cgccgcgacc accagccgct aggttgccgc
     9121 gggtttcgcc gccctgcgga atacgcgcca ggcagtaagg caccggctcg ccgtcgacga
     9181 ccagtacgcg cttatcgcca tctttgatcg cgggcagata gttctgcgcc atgcagtagc
     9241 ggttgcctag ctcggtcagc gtttcggcga taacgcctat gttaggatcg ccttccttaa
     9301 cgcggaaaat ggacgcgccg cccataccgt ccagcggttt cataatgata tcgccgtgct
     9361 tttcccaaaa cgctttgagc tgcgctttat tgcgcgttac cagcgtttcc ggcgtcaggt
     9421 cggcaaacca ggcagtatac agtttttcat tacagtcgcg caggctttgc ggtttgttga
     9481 cgataagcgt cccttcctct tcagcgcgtt ccagaatata ggttgcataa ataaactcgg
     9541 tatcaaacgg cggatctttg cgcatcaaaa tgacgtccag atcggcgagt ttaatctcct
     9601 gctcgctgcc gaactcgtac catttatcgt aattttgctc cacgctcaac gttcgcgtgc
     9661 aggcgcgggc ttcgccgtta atcagataaa ggtcggccat ctccatataa tgaagttcat
     9721 aaccacgacg ttgggcttcc agcagcatag cgaaactggt gtctttcttg atgttgatgt
     9781 gtgcgatggg gtccatcacg atgccgagct tgatcattat tttctccgtt aacgcttcat
     9841 cctaagtcgc caaaacgcac ctgtagcgcg gtaatggcgg tgagcgcggt tgtctcagta
     9901 cgcagaacgc gaggtcctaa cagaatatca gtaaactgat agcgcgcggt catcgcgatt
     9961 tcgtccgccg acagcccgcc ttccgggccg atcagcagtc ggacgcgttc aaccggcagc
    10021 ggcagagtgt tgatgctggc atgggcgcgc ggatgaagat tgagcctcag cccggaatct
    10081 tgctcggcgc accaggcttc cagcgccatc ggcgggcgaa tttccggcac ccggttacgc
    10141 ccgcattgtt cgcaggcggc gatggcgatc ttttgccact gctggcgctt tttgttcaga
    10201 cgttcattat ccagtttaac gccacagcgc tcagagaaca gtggcgtaat gaggcttaca
    10261 cctagttcga tcgatttctg gatagtaaat tccatttttt caccgcgcga catcacctgg
    10321 cccagatgga tatgtagcgg cgattcacga tcgtcgattt cgcctttcat cacttgcact
    10381 tcaacgcttt tcttactggc gctaatgatt tcagcatcga atacctgatt gctgccgtca
    10441 aacagctgta acgcttgtcc cgctcccatg cgcagtacac gaccaatatg gttggccgca
    10501 tcttcgcata acgaaatctg cgtaccggac gtcaacaatt cagggtgata aatgcgggga
    10561 atacgcataa taaaaaaatc cgcgtcatgg ccccggcgtt tggctatcca gggcatgggt
    10621 taacaagaat cccgctagtg taggttagct ctttcgcgcc tggcaagcgc gttgcacata
    10681 gggattatga ttaccctgga ccttcgcgat acgcgcatcg cgctcgcact cccaggcggt
    10741 aacggggtac tgcttatccc agacgttaaa aagctgcgtt tgttggcggg aaagtttcag
    10801 ttggtattgg tcgcgcatat aaaaataagt gcgggcgatt gcgccacggg cgcgggcggg
    10861 cggctcggcg agcttcgctt taaaatccac tttcatggcg cactgcccgt actgaccttc
    10921 gccgccgttc cactggctat acataaagtt gccgcgatcg ccattcactt cgccaatcgc
    10981 gggttgcagg ttatgcatat cgctttccat tttgcagtag accgggtctt tagcgcagtt
    11041 ttttcgcccg ccgtcctgcc agcactggcg ctgatgaccg aattgccagg cggggacaac
    11101 gtgctcccac tcaatgcgtc tggcgcgatt ctcgttttta cgcaccttat agccgcagga
    11161 ctccaggtct acgacgcctt ttttaccctg ccagcggatt tggcacccgc agtaaaagct
    11221 gccgggcgcg tcggcattga ctttgacgct cgccgctttg gcctgagaaa aattgttaat
    11281 gccgtcggcc aatgcctggc ctgaaaacgc tgcggccagc aacgcagcag caaaagaaaa
    11341 attacggtac attgcacact ccatagcaaa acgagcccgc aacgtagcga aagttgtgtc
    11401 tgtatgcaat cagtccgctc aggaaagttc ccggacgttt cggggaacta cccggcgacc
    11461 agtggttcgc cgcagtgaac gcaacgataa accgcttcgc cgcgtaccac acggttatga
    11521 cggcggacgg tgagttgatg ttgctggcat tggcaatggt agggaaaggt attgcgccgt
    11581 acggattgca gcgcaaattg atgagtacgt ctggccggaa cgcccagcac gctttccatc
    11641 atccacttcc attccttgcc atgcggagcc ttgcgtccga agtgcttcca caccaacaga
    11701 tgcgccagtt catgcggcac gacctctgca ataaaggtgt cgatgttttc cagcagtaac
    11761 accgggttga ggcggatttc gtagctctcc agccaggcgg tgcccgccga ggtgccgcgt
    11821 tgcgtataca ccagtttcgg ctccggataa tgtctatcga gcttgaggtt cgcctgggcg
    11881 agattttccc gcagacggcg catcacggcc tgctggatag cgatagggag acgaggggtt
    11941 ttcatagcgg cagagaatag tgcgacggaa gagggactgc aagaaaaacg cttcctcctg
    12001 tggcaggagg aagcgtggag ggattagtcg tgggcgccga tttcgcgcag tttacgacct
    12061 ttcatcaggt tacgttcaat gtgttccagc gaaacgtgtt tggtttccgg caccagccac
    12121 agggtcagca ggataaacag cacgttcagg ccagcgtaga cccagaaggt gttggcgtta
    12181 cccagattgt tcagcatggt caggaacgtt gcgccgacga tcatattggc gatccagttg
    12241 gtcgcggtgg agcaggtgat gccgaaatcg cggcctttga gcggctggat ttcggagcac
    12301 agtacccaaa tcagcggacc agcgctcatc gcaaatccaa tgatgaacat cagcagcata
    12361 gcgatagcga agtattgcgc agacggtgaa tggatgccga tgtgcatcat cgtacccaga
    12421 atccccatac caatcgccat gaccaggaag cccagcgtca gggtcggctt gcggccccag
    12481 cggtcaacca ggccgatagc gatgaaggtt gccagcacgt tagtcagacc aacaataacg
    12541 gtgccccaca tctgctccgt ggtattcgtg taccccgcca gttcgaagat tttcggcgcg
    12601 taatacatga tgacgttcat cccggtaaat tgctgcatta cctgcaacaa aatgccaaga
    12661 aacacggcgc ggcggaagtt gctgttctct ttgaacagcg cccaaccgct ctgtttaacc
    12721 tgcaaacttt cgcgaatttc atcgagctca cgttttgctt ccgcactggt gtcacgcagg
    12781 cgcaacagga cgcgttcagc atcatggaaa cggcgtttcg ccgcaaacca gcgcgggctg
    12841 tccggcagga agaagacgcc gatcagcagc agaatggccg ggatgatgat cacgccgagc
    12901 atccagcgcc atgcgccgct gtagctgaac gcggtatcgg acagataagc gcccagaatc
    12961 ccgatggtga tcatgagttg gtacattgag atcatactgc cgcgaatttt ttccggcgcg
    13021 atctcggaca ggtacaacgg tgcagtgtag gaagcgacgc cgacggccag acccagcagc
    13081 acgcgagaaa taatcaggac ttcaacgtta ggcgccgcag cggagaacag cgaaccggcg
    13141 acgaacagga tagcgccgat catcaggctt tttttacgac ccagcttaaa ggagagccag
    13201 ccgctgccga cagcgccgac ggccgcgcca aacatcatgg agctgaccac ccattcctga
    13261 gtgtgtgcgg taatctgaaa ctcgtcggta atgaagggta aagcaccggc gataacgccg
    13321 atatccaggc caaaaagtaa tcctgccagg gctgcaagaa agcagacaaa aaatgtcatg
    13381 gccttgttgg aacgcccttg ttttttattg tcaggcatta tgccctccgg ttgggttagc
    13441 aattttatcg atgttaagag taggtgagta cgccgtaa
//
LOCUS       DAJVBX010000125        13344 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.125, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000125 DAJVBX010000000
VERSION     DAJVBX010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 13344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13344
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.125"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            123..275
                     /locus_tag="OPV72_003016"
                     /pseudo
     CDS             123..275
                     /locus_tag="OPV72_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309956.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            381..1316
                     /gene="ttcA"
                     /locus_tag="OPV72_003017"
     CDS             381..1316
                     /gene="ttcA"
                     /locus_tag="OPV72_003017"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HCR9915252.1"
                     /translation="MQEIQKNTKKEQYNLNKLQKRLRRNVGEAIADFNMIEEGDRIMV
                     CLSGGKDSYTMLEILRNLQQSAPINFSLVAVNLDQKQPGFPEHILPAYLEQLGVEYKI
                     VEENTYGIVKEKIPEGKTTCSLCSRLRRGILYRTATELGATKIALGHHRDDILQTLFL
                     NMFYGGKMKGMPPKLMSDDGKHIVIRPLAYCREKDIVRFAEAKAFPIIPCNLCGSQPN
                     LQRQVIADMLRDWDKRYPGRIETMFSAMQNVVPSHLCDTNLFDFKGITHGSEVIDGGD
                     LAFDREEIPLQPAGWQPEEDDTALEALRLDVIEVK"
     gene            complement(1360..2734)
                     /gene="dbpA"
                     /locus_tag="OPV72_003018"
                     /pseudo
     CDS             complement(1360..2734)
                     /gene="dbpA"
                     /locus_tag="OPV72_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460614.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase DbpA"
     gene            complement(3221..4204)
                     /gene="zntB"
                     /locus_tag="OPV72_003019"
     CDS             complement(3221..4204)
                     /gene="zntB"
                     /locus_tag="OPV72_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZntB"
                     /protein_id="HCR9915253.1"
                     /translation="MEAIKGSDVNVPDAVFAWLLDGRGGVKPLEDNDVIDSQHPCWLH
                     LNYTHPDSARWLASTPLLPNNVRDALAGESSRPRVSRMGEGTLITLRCINGSTDERPD
                     QLVAMRLYMDERFIVSTRQRKVLALDDVVSDLQEGTGPVDCGGWLVDVCDALTDHASE
                     FIEELHDKIIDLEDNLLDQQIPPRGFLALLRKQLIVMRRYMAPQRDVYARLASERLPW
                     MSDDHRRRMQDIADRLGRGLDEIDACIARTGIMADEIAQVMQESLARRTYTMSLMAMV
                     FLPSTFFTGLFGVNLGGIPGGGWRFGFSLFCILLVVLIGGVTLWLHRSKWL"
     gene            complement(4350..5504)
                     /locus_tag="OPV72_003020"
     CDS             complement(4350..5504)
                     /locus_tag="OPV72_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemoreceptor protein"
                     /protein_id="HCR9915254.1"
                     /translation="MLRNISVRTCIILFMVCTFLLVDTLQITFLHDLPILITCNIIYL
                     ISALLLWWYMTCYLVVPINTAKKSIEEVAAGNLSIHISEFGNNCAGRLIPGINSLSEN
                     ISALVREIRSSSQTAMTLSEQLAARSLSLSVKTEQQSASLIQTAASMDEMAASTKNNA
                     DNTRMASIQADCATQCARKGGELMVRVTENMRSITDCASQMTEIISLIDGIAFQTNIL
                     ALNAAVEAARAGDHGKGFSVVAREVRNLAHRSAEAAKNIKALIDVTHDNVRQGAAIVQ
                     EAEKNMQEIVGGSGQLNVLMSEISTTTREQEKGINQITLALSDLESATHSNVLMVEAL
                     SASSDVLKAQVIELQTKTDKFRLSQPGYSEHALSRSHVSPLSTITRRGQA"
     gene            complement(5915..6478)
                     /gene="smrA"
                     /locus_tag="OPV72_003021"
     CDS             complement(5915..6478)
                     /gene="smrA"
                     /locus_tag="OPV72_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA endonuclease SmrA"
                     /protein_id="HCR9915255.1"
                     /translation="MNLDDKALFLDVMEDVQPLKRHTDVHWQPTRNLKTPQRIDTLQL
                     DNFLTTGFLDILPLNEPLEFRREGLQQGVIDKLRSGKYPQQASLNLLRQPVETCRKML
                     FRFILEAQKEGLRNVLIIHGKGREAKSHANIVRSYVARWLTEFEDVQAYCSALPHHGG
                     GGACYVALRKTVQAKQDNWERHAKRSR"
     gene            6736..7251
                     /gene="ogt"
                     /locus_tag="OPV72_003022"
     CDS             6736..7251
                     /gene="ogt"
                     /locus_tag="OPV72_003022"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HCR9915256.1"
                     /translation="MLRLLEEKIATPLGPLWVVCDEQFRLRAIEWEQYRDRMEQLLNI
                     HYRHEGYERVSATNPGGLSDKLADYFAGNLAVIDTLETATGGTPFQREVWQALRAIPC
                     GQVMHYGQLAAQLGRPGAARAVGAANGANPISIVVPCHRVIGRNGTLTGYAGGVQRKE
                     WLLRHEGYLLL"
     gene            7447..8199
                     /gene="fnr"
                     /locus_tag="OPV72_003023"
     CDS             7447..8199
                     /gene="fnr"
                     /locus_tag="OPV72_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007849744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate/nitrate reduction transcriptional
                     regulator Fnr"
                     /protein_id="HCR9915257.1"
                     /translation="MIPEKRIIRRIQSGGCAIHCQDCSISQLCIPFTLNEHELDQLDN
                     IIERKKPIQKGQTLFKAGDELKSLYAIRSGTIKSYTITEQGDEQITGFHLAGDLVGFD
                     AIGSGHHPSFAQALETSMVCKIPFETLDDLSGKMPNLRQQMMRLMSGEIKGDQDMILL
                     LSKKNAEERLAAFIYNLSRRFAQRGFSPREFRLTMTRGDIGNYLGLTVETISRLLGRF
                     QKSGMLAVKGKYITIENSDALAALAGHTRNVA"
     gene            8350..9297
                     /gene="uspE"
                     /locus_tag="OPV72_003024"
     CDS             8350..9297
                     /gene="uspE"
                     /locus_tag="OPV72_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspE"
                     /protein_id="HCR9915258.1"
                     /translation="MAMYQNMLVVIDPNQDDQPALRRAVYLHQRIGGKIKAFLPIYDF
                     SYEMTTLLSPDERTAMRQGVISQRTAWIREQAKYYLEAGVPIEIKVVWHNRPFEVIIQ
                     EVIAGSHDLVLKMAHQHDRLEAVIFTPTDWHLLRKCPSPVWMVKDQPWPEGGKALVAV
                     NLASEEPYHNALNEKLVKETLQLAEQVNHTEVHLVGAYPVTPINIAIELPEFDPSVYN
                     DAIRGQHLLAMKALRQKFSIDEKVTHVEKGLPEEVIPDLAEHLQAGIVVLGTVGRTGL
                     SAAFLGNTAEQVIDHLRCDLLVIKPDEYQTPVELDDEDD"
     gene            complement(9352..9606)
                     /locus_tag="OPV72_003025"
     CDS             complement(9352..9606)
                     /locus_tag="OPV72_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2534 family protein"
                     /protein_id="HCR9915259.1"
                     /translation="MIMMKLKSAKGKKFLLCLLAVFIVAASVVTRATIGGVIEQYHIP
                     LSEWTSSMYAIQSAMIFVYSLVFTILLAIPLGIYFLGGDE"
     gene            9845..10876
                     /locus_tag="OPV72_003026"
     CDS             9845..10876
                     /locus_tag="OPV72_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HCR9915260.1"
                     /translation="MFTEFFLKNAFNLAILFSCGMALLVVRFWLSRNVQWKKGFTFHA
                     AQFFIYAIIIGTIGSILNNAIEDYNLRFISSGVIDFICTSLIALILTIKLFLIINQFE
                     KAQVNKGRDVTSTRILARVIKITIIVAIVLLYGEHFGMSLSGLLTFGGIGGIAVGMAG
                     KDVLSNFFSGIMLYFDRPFSIGDWIRSPDRNIEGTVAEIGWRITRINTFDHRPLYVPN
                     SVFSSISVENPGRMTNRRIKTVIGLRYEDADKIGLIVDAIRNMLQAHSDIDQKQTLLV
                     YFNEFADSSLNIMVYCFTKTTIWQEWLAVQQDVYLKIIAIVQENGADFAFPSQTLYID
                     DPEAAPAIK"
     gene            complement(10962..11564)
                     /locus_tag="OPV72_003027"
     CDS             complement(10962..11564)
                     /locus_tag="OPV72_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR9915261.1"
                     /translation="MTKKVNLSTTAGADVSTINEAVSQRIKQFRSQKKMSLDELARRS
                     GVSKGMLVEIEGCKANPSIALLCKIAAAMGVSVADFVNVASEPMVHLINRDAIPVLWR
                     GEKGGSAKLMAGTSGPDMLELWQWIMHPGEQFESAGHPADTCELLFVNQGTLTLTVDG
                     RRFIIREGCSAVARTDMPHAYVNDTNEVLEFTMTVNEKSR"
     gene            11608..12294
                     /locus_tag="OPV72_003028"
     CDS             11608..12294
                     /locus_tag="OPV72_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HCR9915262.1"
                     /translation="MSSMLPSISPELARIAPGFRALSINVIAAPVRDAQVGEIALKEA
                     CQAVINGQPAWAQAHIDAWNAVFKAFGAKPKRTPCSAEALRKRVLKDGTMAALDPVVD
                     LYNAVSLRYAVPVGGENSAAYCGSPRLVFADGSETFDTLKEGKPVTESPEPGEVIWRD
                     DRGVTCRRWNWRQGVRTRLSASDKMMWFILESLPEMPVDELYAAENMLTDGLEKMMPG
                     LRFESTLIGV"
     gene            12322..12660
                     /locus_tag="OPV72_003029"
     CDS             12322..12660
                     /locus_tag="OPV72_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915263.1"
                     /translation="MSLFLTSFIFEKKEYDEEFYQLDGWIERYTQTIDGYIGMESYTD
                     AASGRMVNNYYWQTRESMELLINNLQHQQAKSQSHKWLSGYQTIIAEIQGCHNVNLPH
                     PLASFSVPYA"
     gene            complement(12766..13323)
                     /locus_tag="OPV72_003030"
     CDS             complement(12766..13323)
                     /locus_tag="OPV72_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HCR9915264.1"
                     /translation="MAKIIQMLKGEVFMTPTTTQDYISLGQEHAVTFGKTQLTLKPGI
                     LAEGEPLPCTKGLVSHNLLPGYCIPGIKKRIIVVPSLDTPVCEWQVKEYSDRLKSAGS
                     HSNRAVYVLSMDTPFAQARFIREHDIHPGIIFVSDYACRQFLDNSGLKINELSIFARA
                     LIECDENNVVTHVSVPRDITHLPVY"
BASE COUNT         3408 a         3395 c         3192 g         3349 t
ORIGIN      
        1 ccacttgaaa cgtaccatca tcaggacgct gcagcgcctg aatttcagtt gagcccgtca
       61 cttcttaacg ggcctagcta catgatgtat acagttgaca atatccgaag gtactatctc
      121 tattaaaacg tgctggcatt cgtcgccgta atccgtacca tacgcgacat acttttgcct
      181 gctggctgtt gacggcagga gcgaacccgg catttatcgc cagccaaatg gggcatgaaa
      241 ctgcgcatat ggtgtatgaa atttacggta tgtagattga tgacatgaac gacgaacaag
      301 tagcgatgtt gaatgcgcgg ttatcgtagt tgcaaagttt gcccccaatt tgccccattt
      361 agtaccagag aactgaaata atgcaagaaa ttcaaaagaa tacaaagaaa gaacaataca
      421 acctcaacaa gttgcaaaag cgcctgcgcc gtaacgttgg cgaagcgatt gccgatttta
      481 atatgattga agaaggcgat cgcattatgg tttgcctttc tggcggcaaa gatagctata
      541 cgatgctgga aattttacgt aatttgcagc aaagcgcccc gatcaatttt tcactggtcg
      601 ccgtcaacct cgatcaaaag cagccaggtt ttccggagca tatcctgcca gcctaccttg
      661 agcagctggg cgtagaatat aaaatcgtcg aagaaaacac ctacggcatt gtgaaagaga
      721 agattccgga aggaaaaacc acctgctcgc tgtgctcgcg tttgcgtcgg ggtatcctgt
      781 atcgtactgc gactgaactg ggcgcgacca aaatcgccct gggccaccat cgcgacgata
      841 ttctgcaaac cctgtttctg aatatgttct atggcggaaa aatgaaaggg atgccgccga
      901 agctgatgag cgatgacggc aaacatatcg tgatccgccc gctggcttac tgccgcgaga
      961 aagatattgt ccgttttgct gaggccaaag cctttcctat cattccttgt aatctgtgcg
     1021 gttcgcaacc caacctgcaa cgccaggtga ttgccgacat gctacgcgac tgggataagc
     1081 gctatcctgg acggatcgag acgatgttta gcgccatgca gaatgtcgtg ccgtctcacc
     1141 tttgtgacac aaacctgttc gatttcaaag ggataactca cggttccgag gtcatcgacg
     1201 gcggtgattt agcgttcgat cgtgaagaga ttccattgca gcccgctggc tggcagccgg
     1261 aagaagatga caccgcctta gaggcgttgc ggcttgatgt tatcgaagtg aaataatctg
     1321 caggcgtctc agcactccgc tgagacgcca tactatcgat cattttaata gccgtacccg
     1381 gcatgacttg cctttgatct tcccgttttg caactgcttc caggcttttt gcgctactgc
     1441 ttgacgtacg gcgacgtaaa cgtgcatggg atgcacgtta attttgccaa tatccgcccc
     1501 gtccaatcca atatcgccgg tcagcgcgcc taaaatatct cccggacgca ttttcgcttt
     1561 tttgccgccg tcaatgcata gggtagccat ctctgcggcc agagggagta acggctgccg
     1621 ggcgggcgca ttcagccagt tcagcttgag ttgcagcatt tctgaaagaa tattcgcccg
     1681 ctgcgcctct tccggcgcac agaaactgat cgccaggccg ctgcttcccg cgcgcgccgt
     1741 acggccaata cgatggacat gcacctccgg gtcccaggcc agctcatagt taaccaccag
     1801 ttcgagcgat ttaatgtcta accctcgcgc ggcaacgtcg gtggcaacca gaatgcgcgc
     1861 gctgccattt gcaaaacgca ccaacgtctg gtcgcggtcg cgttgttcca gatcgccgtg
     1921 gagcgccaac gcgctttgtc ctaccgcatt aagcgcatca caaacggcct gacaatcttt
     1981 tttggtattg caaaacacca cgcaggacgc tggctgatgc tggctaagca acgtttgtag
     2041 cagcgaaatt ttttcatgcg ccgacgtttc gaagaactgc tgttcgatag ccggtagcgc
     2101 atctaccgta tcgatttcaa tacgtattgg ctgctgctgt acacgaccgc taatcgccgc
     2161 aatggcctca ggccaggttg ctgaaaacaa caacgtctgg cgcgtcgcag gcgcaaagcg
     2221 gatcacctca tcaatggcgt cactgaatcc catgtccagc attcggtctg cttcatccat
     2281 taccagaatg tgcagcgcat ccagcgatac ggtttctttt tgtaaatgat ccagcaggcg
     2341 ccccggcgtc gcgacaatga tatgcggagc gtgctgaagc gagtcgcgct gtgcgccaaa
     2401 gggctgcccg ccacacaagg tcagaatttt ggtatttggc agaaaacggg ccaggcgacg
     2461 taactccccg gctacctgat ccgccagctc ccgcgtcggg cacagcacta atgcctgtgt
     2521 ctggaacaga gtgacatcaa ttcgatgcaa gagcccaaga ccaaacgccg ccgttttacc
     2581 gctaccggtc ctggccttgc acacgcacat cattacccgc cagaatgacg ggtaatgctg
     2641 cggcctggac aggcgtcatc tcaagatagc ccagctcagt aaggttattg agctgggcgg
     2701 cgggcaaaac attcagggtt gaaaaagcgg tcacaattta ctctcgcggt aacgactcat
     2761 agtcagcagg cgcgtatcct cgcagatccg gacgtttgat gcgacatttt aatcggttct
     2821 tcgtccggcg gcgggtcggg catcggctga ggacggggaa gcggctcagg aatgggaaca
     2881 gggtcagtgg gaatcgggtc cgacaaggac gagtgtagat ataataaggt caaaagacag
     2941 ctcatattac cctccagaat gtcattcaga ctcttaaagg gtagacgctg atatcctaca
     3001 ggcaaaaaaa agccgactaa tctaagccgg cgtcgtacga atcaattgtg ctatgcagta
     3061 attcaaaaaa ggaagcaaga caatatagaa cgcaacgccc atcgcttgac gttgcattca
     3121 cctgcgagag agatattgcc ccgaataggt agatggttta ttgacttcgc tcaaatttct
     3181 cggcgttttt tcacccaaaa cggtctgaaa agcgcttttg ttacaaccat ttactgcgat
     3241 gcaaccataa agtaacacca ccgatcagga caactaacag aatacaaaac agagaaaagc
     3301 cgaaccgcca tccgccgcca ggaataccgc ccaggttaac gccaaataac cccgtgaaga
     3361 aggtgctggg cagaaaaacc atcgccataa gcgacatggt ataagttctg cgcgccagag
     3421 actcctgcat cacctgggca atttcatccg ccatgatgcc agtacgcgcg atacaagcgt
     3481 caatttcatc cagccccctt cccagcctgt cggcgatatc ctgcattctg cgccggtgat
     3541 cgtcgctcat ccacggcagc cgttcactcg caagccgggc atagacgtcg cgctgcggcg
     3601 ccatatagcg gcgcataaca attagctgtt tacgtagcaa cgcgaggaaa ccgcgcggtg
     3661 ggatttgctg gtcgagaaga ttatcttcca gatcgataat tttatcgtgt agctcttcaa
     3721 taaattcact ggcgtgatcg gttaacgcat cgcatacatc cactaaccag ccgccgcaat
     3781 ctacgggccc ggtgccctcc tgcaaatcac tgaccacatc gtccagcgcc agaacctttc
     3841 gctgacgggt agacacaatg aaccgctcgt ccatatataa acgcattgct actaattgat
     3901 ccgggcgttc gtcagtactg ccattaatac agcgcagcgt aatgagcgtc ccttccccca
     3961 tacgacttac gcgcgggcgc gagctttcac cagccagcgc atcacgcacg ttattgggga
     4021 gtaaaggcgt tgaagccaac cagcgggcgc tgtccgggtg ggtataatta agatgtagcc
     4081 aacagggatg ctgactatcg atcacatcat tatcttcgag cggttttact ccaccacgac
     4141 catccagtag ccatgcgaaa acggcatccg gcacgttcac atccgatccc ttaatggctt
     4201 ccacagcgcc tccacgttac aactctcatg ccgttagtct agctttcggg aaaggttaag
     4261 caatctctca ttttctcatt gcgcaaaaag aatgacggga acgtgcgaaa aaagcgcctt
     4321 agcaacaggc gcttaccaaa catgtattat caggcctggc cgcgcctggt gatggtcgaa
     4381 agaggtgata catgagagcg cgacagcgca tgttcactgt aacccggctg gcttaaacga
     4441 aatttgtcgg ttttagtctg taactcgatc acctgcgcct ttaaaacatc cgaagaagca
     4501 gatagcgctt caaccattaa gacattgcta tgggttgcgc tttccagatc gctcaacgcc
     4561 agggttatct ggttaatgcc tttttcctgc tcccgcgtgg tggtggaaat ttcactcatc
     4621 agcacgttta attgcccgga gccgccaaca atctcctgca tatttttttc agcctcctgc
     4681 actatggcgg ccccctgccg cacattgtca tgcgtaacgt cgatcagcgc cttgatattt
     4741 tttgccgcct cagcgctacg atgcgccaga ttacgcactt ccctggccac cacggagaaa
     4801 ccttttccat gatcgcccgc ccgcgcagcc tctaccgccg cgttaagcgc cagaatatta
     4861 gtctggaatg cgataccgtc aatcaatgaa ataatctccg tcatctgcga ggcacagtcg
     4921 gtaatagaac gcatattttc tgtaacccgc accattaact caccgccttt acgggcgcat
     4981 tgggttgcac aatccgcctg tatgctcgcc attcgggtat tatccgcatt gtttttggta
     5041 ctcgccgcca tttcatccat actggcggca gtttgaatta acgaggccga ctgctgttcc
     5101 gtctttacgg atagcgacag actgcgcgcc gccagttgtt cggaaagggt cattgccgtt
     5161 tgcgaagagg atctgatttc acgtaccagc gcggaaatat tctccgacag gctattaatc
     5221 ccggggatga gtcgcccggc gcaattattg ccaaattcgg agatatgaat agacaagttt
     5281 cctgctgcga cctcttcaat acttttcttc gcggtattaa ttggcactac cagatagcag
     5341 gtcatatacc accaaagcag taatgccgag atcagataaa tgatattaca cgtaattaaa
     5401 atagggagat cgtgcagaaa ggttatttgt aaagtatcca ctaaaagaaa cgtacatacc
     5461 atgaatagaa taatgcatgt cctgacgctg atatttctca acatttttga cggcctacaa
     5521 ccaggatagg agacaggttt tatttttata gcatttcaga tacctattgc cattcgtttc
     5581 tttgacattc tccatattca ataccagacc atcgccattt cccttagtgc aatagataaa
     5641 atcatctata ttcgctatgc caggatattc atccatccat attgacaagt gatgtactta
     5701 tcaccatttt ctgcttaata gttaagtcga aagccagtat attttaatag acgcttaaat
     5761 aagtgaatga ctgtttctcc gtgttattac tgtggacagc gttatcgccc gttctcttgc
     5821 agaatcctga gcgtttggat gaggcgttat atcaggcata aaatcgggtt catgcgagct
     5881 tgcgctggcg gtcctgtccg ccagcggcaa cgatttaccg actacgcttc gcatggcgct
     5941 cccagttatc ctgtttagcc tgcaccgttt tacgtaaagc gacataacat gccccgccgc
     6001 cgccatggtg cggcagcgcc gaacaataag cctgtacatc ctcaaactct gtcaaccagc
     6061 gggccacata gcttcggacg atattggcat gcgacttcgc ctctcgccct ttaccatgaa
     6121 tgatcaggac attacgcaac ccctctttct gcgcctccag gataaaacga aacagcattt
     6181 ttcggcacgt ttcgaccggt tggcgtaaca aattgaggct ggcctgctga gggtatttcc
     6241 cactgcgtaa cttgtcgatg acaccctgct gcaatccttc ccgacgaaat tccagcggtt
     6301 cattcagcgg cagaatatcc agaaagcccg tcgtcaggaa attatcaagc tgaagcgtgt
     6361 cgatacgctg gggcgtttta agattacgcg ttggctgcca gtgtacatca gtatggcgtt
     6421 tcagcggctg gacatcctcc atgacgtcaa gaaacagcgc tttatcgtca aggttcatgg
     6481 ttcatcctcc agcgtttttg cgactgccgt tatcataacc gtgccctgtt ataccgacaa
     6541 cggtttacag ttatttccaa taacagcgac aatgtcaggc aattaaccgt ctcgccaggc
     6601 tccctttttc tccgccaacg atattactgt cgctaaatgt gttatccctg actatctttt
     6661 aaggagtatg gttgcgggta ttcctggcat gatatcttgt ctcttacgtt agattaagac
     6721 gatgtgagag aacggatgct gagattactt gaagagaaga tagccacgcc attaggtccg
     6781 ttatgggtgg tttgcgatga gcagtttcga ctgcgggcca ttgagtggga acagtaccgc
     6841 gatcgtatgg agcaactgct aaatatccac taccgtcacg aaggctatga acgcgtttct
     6901 gcgactaacc ccggtggact cagcgataag cttgcagatt attttgcagg caatctcgcc
     6961 gtaattgata ccttggaaac cgccacgggg ggcacacctt ttcaacggga agtatggcag
     7021 gcgttgcgcg ctatcccctg cgggcaagtg atgcactatg gccaactggc ggcgcaactg
     7081 ggacgaccgg gcgccgcacg cgcagtgggt gctgcgaatg gcgctaaccc catcagtatt
     7141 gttgttccct gccatcgcgt catcgggcgt aacggcactc tgaccggata cgcaggcggc
     7201 gtgcagcgaa aagagtggct attacgccat gaaggctatc ttttattatg aatatacagg
     7261 caaaaagtgc cttatcggtc acacttttat gtaaagtagc aacaaataaa ttacgtattt
     7321 tcaaatagat ataagtattc atcaaactta tacttgaatt attccttctc cgggatagct
     7381 cagacttacg cgctcaccaa aaagatgtta aaattgacaa atatcaatta cggcttgagc
     7441 agacctatga tcccggaaaa gcgaattata cggcgcattc agtctggcgg ttgtgctatc
     7501 cattgccagg attgcagtat cagccagctt tgcatcccgt tcacacttaa cgagcatgag
     7561 cttgatcagc ttgataatat catcgagcgc aaaaagccca ttcagaaagg gcaaactctg
     7621 tttaaagcag gtgatgaact gaaatcgctc tatgctatcc gctccggaac gattaagagc
     7681 tacaccatta ccgagcaagg cgatgagcag attactggat tccatttagc aggcgacctg
     7741 gtgggttttg acgccattgg cagcggtcat catccgagct ttgcacaggc gctggaaacc
     7801 tcaatggtat gtaaaatccc ctttgagaca ctggatgacc tgtccggcaa aatgcctaac
     7861 ctgcgtcagc aaatgatgcg tctgatgagc ggtgaaatta aaggcgatca ggatatgatc
     7921 ctgttattgt cgaagaaaaa cgccgaagaa cgtctggctg cgtttattta caacctgtcc
     7981 cgccgctttg cgcagcgtgg tttttcaccg cgtgaattcc gcctgacgat gacccgtggc
     8041 gatatcggca actatcttgg cttaacggtc gaaaccatta gccgtctgct ggggcgtttc
     8101 cagaaaagcg gtatgctggc ggtgaaaggt aagtatatta ctattgaaaa cagcgatgcg
     8161 ctggcggccc tcgccggtca tacccgcaac gtcgcttaaa cgtcagctaa accattgatg
     8221 ttatcttctg ccatatcgtt aaatttttct catttattga tctggcagaa gcgcttcccc
     8281 tgtttcattc accatatttg agttactctt tagttacaaa ctgcgatgac agttgtaagg
     8341 agaccctgta tggctatgta tcaaaatatg ctggtggtca tcgatcccaa tcaggacgac
     8401 caacccgcat tacggcgagc agtttatttg catcaacgga ttggcggcaa aattaaagct
     8461 ttcctgccta tttacgattt ctcgtatgag atgaccaccc tgctttctcc tgacgaacgc
     8521 accgcaatgc gtcagggcgt aataagtcaa cgcacagcct ggatacgtga gcaggcgaaa
     8581 tattatcttg aagccggtgt ccccattgaa ataaaagtgg tctggcacaa tcgtcccttt
     8641 gaggtcatca tccaggaggt tatcgccggc agtcacgatc tggtgttgaa aatggcgcat
     8701 cagcacgatc gactggaagc ggtcattttt acccctaccg actggcattt gctgcgtaaa
     8761 tgcccaagcc ccgtgtggat ggtcaaagat cagccgtggc cagagggcgg caaagccctg
     8821 gtcgccgtga acctggcaag cgaagagccc tatcacaatg ctctcaacga aaagctggta
     8881 aaagagacct tacaattggc ggagcaggtt aatcataccg aagtacacct ggtcggcgcc
     8941 taccccgtta cgccaatcaa tatcgccatt gaactgccgg aatttgatcc cagcgtgtat
     9001 aacgacgcca tcagaggcca gcatttactg gcgatgaaag cgctgcgcca gaaattcagc
     9061 atcgatgaaa aagttacgca tgtagaaaaa ggcttgccgg aagaagttat cccggatctt
     9121 gccgaacatc tccaggcggg gatcgttgtg cttggcaccg ttggacgtac cggactctcg
     9181 gccgcgtttt tggggaacac ggccgaacag gtcattgacc atctgcgctg cgacctgtta
     9241 gtcattaagc ctgatgagta tcaaacaccg gttgaactgg acgacgagga cgattaatcc
     9301 ctcttccgtc ctgccggatg gcgctgccat ccggccaaca cctcattcct gttactcatc
     9361 tccgccgagg aaatagatcc ccaaaggaat cgccagcaga atagtgaaca ccagactgta
     9421 aacgaaaatc attgccgact gaatggcata catagagctt gtccactcgg acagtggaat
     9481 atgatattgc tcaatcacac cgccgatagt cgcgcgcgtt accaccgatg ccgcaacgat
     9541 aaacactgcc agcaggcata acagaaattt tttccccttc gccgatttca gcttcatcat
     9601 gatcatagta ttgtccttta cagatgactt tgttacctga tagcaacaat accatgacaa
     9661 tcacgcgatg tctgctccat aaaacgtaac attgtattta cataaaaagt aaaccgctga
     9721 gattaaagct gatagcacta tttcttcttt ttacttatcg atgatctacg cgtttatcct
     9781 gggtaaaata cctgttaatc aggtcattct gagctgttat cgtaggaagg agcggaaaac
     9841 aataatgttc actgaatttt ttctcaaaaa cgcatttaat ctggcgatac ttttcagttg
     9901 cggtatggcg ttgctggtcg tgagattttg gctcagccgt aacgtacagt ggaagaaagg
     9961 attcacgttc catgcggcac agttttttat ttacgcgatt attattggaa ccatcgggag
    10021 catcctgaat aatgctattg aagattataa tttgcgtttt atctcttccg gggtcattga
    10081 ttttatctgc acctcgctca ttgcgcttat tctgacgata aaacttttcc tgattattaa
    10141 ccaatttgaa aaagcacagg tcaataaagg tagagatgtc accagtaccc gtattctggc
    10201 acgggtcata aaaataacca ttattgtcgc gattgtctta ctgtatggcg aacattttgg
    10261 catgagtctg tccggtctgc tgacctttgg cggtatcggc ggtatcgctg ttggtatggc
    10321 gggcaaagat gtcctgagca attttttctc cggtattatg ctctatttcg atcgcccctt
    10381 cagtatcgga gactggattc gttctcctga cagaaatatc gaaggtacgg tcgccgaaat
    10441 cggctggcga attacacgaa ttaacacatt cgaccaccgc ccgttgtacg tgcctaattc
    10501 cgtcttttca tccattagcg ttgagaatcc gggacggatg accaaccgtc gaataaaaac
    10561 ggttattgga ttacgttacg aagatgccga caaaattggc ctcattgttg acgctatcag
    10621 aaacatgctg caggcgcaca gcgatatcga tcagaaacag acgctgttgg tctattttaa
    10681 tgaattcgcc gactcttcgc tgaatattat ggtgtattgc tttaccaaaa caacaatatg
    10741 gcaggaatgg cttgctgtac agcaggatgt ttacctgaaa attattgcga ttgtccagga
    10801 aaacggcgct gacttcgcct tcccaagcca gacgctatat atcgatgacc cggaggccgc
    10861 gcctgcgata aaataaaaga tagccggtgc ccgataacgc ttatcgggca ccgaggcttc
    10921 cctgtccgga tgacgggttg ttagcgcctt ccttacggtg atcaacggct cttttcattc
    10981 accgtcatgg taaattcaag cacctcatta gtgtcgttaa cgtaggcatg aggcatatcg
    11041 gttctggcta cagcggagca gccctcccga ataataaagc gtctaccgtc gactgttaat
    11101 gtcagtgttc cctgattaac aaacagtaat tcacaggtgt ctgccggatg ccctgccgac
    11161 tcaaactgtt caccaggatg cattatccat tgccatagtt ccagcatatc cggcccgctg
    11221 gttcccgcca ttagttttgc actgccgcct ttctcgccgc gccacaacac cggaatagca
    11281 tcccggttga taagatgaac catcggctcg ctggcgacgt tgacaaaatc cgccacggac
    11341 actcccattg ccgccgcgat cttacataac agcgcaatgc ttggattagc tttacagcct
    11401 tcaatttcca ccagcattcc tttactgacg ccggaacgcc gcgcaagctc atccagcgac
    11461 atcttttttt ggctacgaaa ttgtttgata cgttgggaaa cagcttcatt tattgtgctg
    11521 acgtcggcgc ccgccgtggt cgataagttg acttttttgg tcattggtcg atatcataga
    11581 ataaaatagt cattacagga ttatgcgatg tcttctatgt taccgtcaat cagcccggaa
    11641 ctggcccgta tcgctcccgg ctttcgtgca ttaagtatta atgttattgc cgctccggtt
    11701 cgcgatgcgc aggtcggaga aatcgcgtta aaagaggcct gtcaggccgt aattaacgga
    11761 caaccggcgt gggcacaggc gcatatagac gcctggaatg cggtgtttaa agcattcggc
    11821 gcaaaaccaa agcgcacccc ctgctcggct gaagcgctac gaaaacgcgt gttgaaggat
    11881 ggaacaatgg cggcgctgga cccggtcgtt gatctttata acgcggtgag cctgcgctat
    11941 gccgtgccgg taggcggcga aaatagcgcg gcttattgtg gatcgccgcg gctggttttc
    12001 gcagacggta gtgaaacatt tgataccctg aaagaaggaa aacccgttac cgagtcgcca
    12061 gaaccaggcg aagttatctg gcgcgatgac agaggcgtca cctgtcggcg ctggaactgg
    12121 cgtcagggag tacgtacccg actaagcgct tcagataaaa tgatgtggtt tatccttgaa
    12181 agcttgccgg aaatgccggt tgatgaattg tacgcggcag aaaacatgct gactgacggc
    12241 cttgaaaaaa tgatgccagg tttacgtttt gaatccacgt tgataggtgt ttgattgata
    12301 ttgcgtaaca ggagaaatac catgtcgctg tttctgacaa gttttatttt cgaaaaaaaa
    12361 gagtacgacg aagagtttta tcaactggat ggctggattg agcgctatac acagactatt
    12421 gatggctata ttgggatgga aagctatacc gatgccgcca gcggaagaat ggttaataat
    12481 tattactggc agacccgcga atcaatggag ctattgataa ataatttaca gcaccagcag
    12541 gccaaatcac aaagtcataa gtggctttcc ggttaccaga cgattattgc agaaattcag
    12601 gggtgccata acgttaacct gccccatccg ctggcatcat tttcagttcc ctatgcgtga
    12661 tgcaatagta tatgtattaa atgtgggggc acacaggaga atgcctgcgc ccctgcattg
    12721 ccagttattc ggttttctgt gcaggggcgg cgctgatata agtgattaat agacaggaag
    12781 atgagtgata tctcgtggta cactaacatg cgtaaccaca ttgttttcat cgcactcaat
    12841 caacgctctg gcaaaaatac tgagctcatt aattttcagc ccggaattat ccaaaaactg
    12901 gcggcaagcg tagtcagaaa caaaaattat gccgggatga atatcatgtt cccgaataaa
    12961 acgggcctga gcaaatggcg tatccatact caacacatat actgcccggt ttgagtggct
    13021 acccgctgat ttaaggcggt cactatattc ttttacctgc cattcacaaa ccggcgtatc
    13081 cagtgacggg acgacaataa tccgcttttt tatccccggg atacagtaac ccggtaataa
    13141 attatggctc accagcccct ttgtgcaggg taatggttcg ccttcagcca gtataccggg
    13201 tttgagggtc agttgcgttt tgccaaaggt cacagcgtgt tcctgaccca atgagatata
    13261 atcttgtgtt gttgttggcg tcataaaaac ttctcctttt aacatttgta ttattttagc
    13321 cataataatt atttagcaat ccgc
//
LOCUS       DAJVBX010000126        13334 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.126, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000126 DAJVBX010000000
VERSION     DAJVBX010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 13334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13334
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.126"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(1..273)
                     /locus_tag="OPV72_003031"
                     /pseudo
     CDS             complement(1..273)
                     /locus_tag="OPV72_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461634.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
     gene            complement(277..1047)
                     /locus_tag="OPV72_003032"
                     /pseudo
     CDS             complement(277..1047)
                     /locus_tag="OPV72_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461634.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
     gene            complement(1044..1649)
                     /locus_tag="OPV72_003033"
     CDS             complement(1044..1649)
                     /locus_tag="OPV72_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein I"
                     /protein_id="HCR9915265.1"
                     /translation="MNSLLPPGSTPLERRLAQTCSGISDLQVPLRDLWNPATCPVSFL
                     PYLAWAFSVDRWDEGWTESVKRQVVKDAFYIHQHKGTTSAVRRVVEPFGFLIHIIEWW
                     QTGEAPGTFRLDIGVQDQGITEDTYLELERLISDAKPCSRHMIGMSINLQTSGPHWVG
                     AASYLGEEITIYPYINETIISGGTAHEGGAVHVIDTMRVNP"
     gene            complement(1642..2550)
                     /locus_tag="OPV72_003034"
     CDS             complement(1642..2550)
                     /locus_tag="OPV72_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate assembly protein"
                     /protein_id="HCR9915266.1"
                     /translation="MAVIDLSRLPAPQIVDVPDFETLLAERKAAFVALYPVDEQDAVR
                     RTLALESEPVTKLLQESTYREILLRQRINEAAQAVMVAYSMGNDLEQLAANCNVKRLT
                     VVPADNDAVPPVAAVMEDDEALRQRIPAAFEGLSVAGPTGAYEFHARSADGRVADASA
                     TSPAPAEVVLTVLSREGDGTAEKDLLDVVEKALNSENVRPVADRLTVRSAEIIPYRVE
                     ATIFLYPGPEAEPVMAAAKASLQKYIASQTRLGRDIRRSAIFAALHVEGVQRVELASP
                     LADMVLNKTQAASCTQWSVTNGGTDE"
     gene            complement(2537..2896)
                     /locus_tag="OPV72_003035"
     CDS             complement(2537..2896)
                     /locus_tag="OPV72_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013098787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPW/gp25 family protein"
                     /protein_id="HCR9915267.1"
                     /translation="MTLYIGMSRNDGQVIADTDHLRQSVRDILLTPQGSRLARREYGS
                     LLSALIDQPQNPALRLQIMSAVYVALNRWEPRLTLDSITINGNFDGSMVVELTGQRNN
                     GAPVSLSVTTGADNGSD"
     gene            complement(2893..3471)
                     /locus_tag="OPV72_003036"
     CDS             complement(2893..3471)
                     /locus_tag="OPV72_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate assembly protein V"
                     /protein_id="HCR9915268.1"
                     /translation="MNAQLTEIMRLITNLIRTGTVTEVDRENWLCRVKVGELETNWIN
                     WLTLRAGGARTWWCPSPDEQVVVLSMGGNLETAFVLPAIYSNQFAPPSDSVDGCVTEY
                     PDGGWFEYEPATGRWHVRGIKSMVIEAADNITLKTGEFVVEADTTRINSEVVINGGVT
                     QGGGAMSSNGVVMDKHGHTGVKSGGDTSGGPV"
     gene            complement(3540..3986)
                     /locus_tag="OPV72_003037"
     CDS             complement(3540..3986)
                     /locus_tag="OPV72_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage virion morphogenesis protein"
                     /protein_id="HCR9915269.1"
                     /translation="MDELQKVDDWLTALLANLEPAARNRMMRQLAQQLRRTQQQNIRL
                     QRNPDGIGYEPRRVTARSKKGRIKRQMFAKLRTTKYLKTAASADSASVQFDGKVQRIA
                     RVHHYGLRDRVSRKGPEVRYAERRLLGVNDEVETITRDTLLRWLAG"
     gene            complement(3979..4410)
                     /locus_tag="OPV72_003038"
     CDS             complement(3979..4410)
                     /locus_tag="OPV72_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCR9915270.1"
                     /translation="MNKPQSLRSALNKVVAYVRDNPDKLHLFVDNGSLVATGASSMSW
                     EYRYTLNVVIEDFSGDQNLLMAPVLLWLSTSQPDAINNPDLREKLFTFEVDILRNDVC
                     DISMNLQLTERVLVSTDGSVSSVEAVPEPDEPEEMWTVKRG"
     gene            complement(4506..4934)
                     /locus_tag="OPV72_003039"
     CDS             complement(4506..4934)
                     /locus_tag="OPV72_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysB family phage lysis regulatory protein"
                     /protein_id="HCR9915271.1"
                     /translation="MMRALAVVLALALAALGWQSWRLNNASHTIETQGAALKSKTQEL
                     TKKNSQLIGLSILTETNSREQTRLYAAAEQTTALLRSRQRRIEELKSENEDLRRWADT
                     PLPADIIRLRDRPALAGGAAYREWLSQSDAVPPGKVSAAQ"
     gene            complement(4931..5308)
                     /locus_tag="OPV72_003040"
     CDS             complement(4931..5308)
                     /locus_tag="OPV72_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010835207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HCR9915272.1"
                     /translation="MKKKVMSVFFQLAWAALLVISLLYPRSGAPVLVGASVQVSCFLA
                     WLLAALCAVGWFAGDRARDEARAALIKFRAHPVKPVRTWAIRLLIVLCLAFSGWVITL
                     VFYLLTLVLYQIARSQLHEPMAA"
     gene            complement(5313..5822)
                     /locus_tag="OPV72_003041"
     CDS             complement(5313..5822)
                     /locus_tag="OPV72_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme"
                     /protein_id="HCR9915273.1"
                     /translation="MNTSIVKCCLVGAVLAIAATLPGFQSLHTSVEGLKLIADYEGCR
                     LQPYQCSAGVWTDGIGNTSGVVPGKTITERQAAQGLITNVLRVERALEKCVVQPMPQK
                     VYDAVVSFAFNVGTGNACSSTLVKLLNQRRWADACHQLPRWVYVKGVFNQGLDNRRAR
                     EMAWCLKGA"
     gene            complement(5803..6018)
                     /locus_tag="OPV72_003042"
     CDS             complement(5803..6018)
                     /locus_tag="OPV72_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915274.1"
                     /translation="MTLERISAFITYCIAVLLAWLGDLSLKDASTVGGVLIGVLMLAI
                     NWYYKHQSFKLLRGGKISRGEYEYFNR"
     gene            complement(6022..6225)
                     /locus_tag="OPV72_003043"
     CDS             complement(6022..6225)
                     /locus_tag="OPV72_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail protein X"
                     /protein_id="HCR9915275.1"
                     /translation="MKVRAHQYDTVDALCWRHYGRTQGVTEQVLQANPGLAEYGPFLP
                     HGLQVELPDITASTTAQTVQLWD"
     gene            complement(6225..6689)
                     /locus_tag="OPV72_003044"
     CDS             complement(6225..6689)
                     /locus_tag="OPV72_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head completion/stabilization protein"
                     /protein_id="HCR9915276.1"
                     /translation="MKFVAPEQAPEQAEVIKNTPFWPDVNLSEFRSVMRTDGTVTQPR
                     LKQVVLTAISEVNAELYDFRNRQQMLGWRTLAEVPAEMLDGKSERIRHYHNAVFCWAR
                     AVLNERYQDYDATASGVKRGEELAEASGDLWRDARWAISRVQDAPHCTVELI"
     gene            complement(6783..7433)
                     /locus_tag="OPV72_003045"
     CDS             complement(6783..7433)
                     /locus_tag="OPV72_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase endonuclease subunit"
                     /protein_id="HCR9915277.1"
                     /translation="MSLSPARQHRLRIQAEQAAREGGSVRHASGYDLMLLQLAEDRRR
                     LKGVQSTVKKAEIKVELLPKYSAWAEGVLAAGGAQQDDVLMYVMLWRIDAGDYAGALE
                     IGRHALRHGWVMPLGNRNVQTVLAEEMADAAQSALLAAAGFDADPLLQTLDLTTDLDM
                     PDQSRARLHKAIGAVLSESNPASALNHLNHALQLDPRCGVKKEKQQLERRLRNDSR"
     gene            complement(7437..8501)
                     /locus_tag="OPV72_003046"
     CDS             complement(7437..8501)
                     /locus_tag="OPV72_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006894826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein, P2 family"
                     /protein_id="HCR9915278.1"
                     /translation="MKKKTRFAFNAYLQQLARLNGVDVEELSSKFTVEPSVQQTLEDH
                     IQQSAAFLTLINITPVTEQSGQLLGLGVGSTIAGTTDTTTKEREPTDPTLMEDVEYKC
                     EQTNFDTVLTYAKLDLWAKFQDFQVRIRNAIVKRQALDRIMIGFNGVKRAKTSNRAEN
                     PLLQDVNKGWLQKIREDAPDHVMGSKTAEDGTTTAEPVKVGPGGKYVNLDAVVMDTVN
                     ELIDVEYQDDDELVVVCGRELLSDKYFPLVNKEQDNSEKIAADLIISQKRMGGLQAVR
                     APFFPANALLITRLDNLSIYWQEDTRRRSVIDNPKRDRIENFESVNEAYVVEDYRCAA
                     LVENIEIGDFSAPAAPESGE"
     gene            complement(8518..9351)
                     /locus_tag="OPV72_003047"
     CDS             complement(8518..9351)
                     /locus_tag="OPV72_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPO family capsid scaffolding protein"
                     /protein_id="HCR9915279.1"
                     /translation="MTVKAKRFRIGVEGATTDGREIQREWLVQMAASYNPTVYTALIN
                     LEHIKSYLPESTFNRYGRVTGLVAEEIQDGPLAGKMALYADIEPTDALVELVKKGQKL
                     FTSMEVSTKFADTGKAYLVGLGATDDPASLGTEMLAFSASAAHNPLANRKQNPENLFS
                     EAVETLIELEEAQDEKPSLFASVTALFTKKEQTDDARFSDVHKAVELVATEQQNLSER
                     TDKSLAENGERLSALESSLQEQQTAFAELQQQLSREDSRKDYRQRAPGGDAPAGTLTN
                     C"
     gene            9494..11260
                     /locus_tag="OPV72_003048"
     CDS             9494..11260
                     /locus_tag="OPV72_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase ATPase subunit family protein"
                     /protein_id="HCR9915280.1"
                     /translation="MNTTLTPADLDPRRQAMLLYFQGYRVARIAEMLGEKVATVHSWK
                     KRDKWGDYGPLDQMQLTTAARYCQLIMKEQKEGKDFKEIDLLARQSERHARIGKFNDG
                     GNEADLNPKVANRNKGPRRQPEKNVFSDEQIEKLEEVFHASMFDYQRHWFEAGKINRI
                     RNLLKSRQIGATFYFAREALIDALLTGRNQIFLSASKAQAHVFKQYIIDFAKEVEVEL
                     KGDPMVLPNGAALYFLGTNARTAQSYHGNLYLDEYFWIPKFQELRKVASGMAIHKKWR
                     QTYFSTPSSLTHSAYPFWSGALFNRGRAKADKVDIDLTHSNLARGLLCPDGQYRQIVT
                     VEDAVRGGCNLFDLDQLRMEYSPDEYQNLLMCEFIDDLASVFPLSELQACMVDSWEVW
                     TDFQALALRPFGWREVWIGYDPAKGTQNGDSAGCVVIAPPTVPGGKFRILERHQWRGM
                     DFRAQADAIKKLTQQYNVTYIGIDSTGVGHGVYLNVKDFFPAVREFVYNPNVKNALVL
                     KAYDIISHRRLEFDAGHTDIAQSFMAIRRATTASGNRPTYEASRSEEASHADLAWATM
                     HALFNEPLQGEAANTSNIVEIF"
     gene            11260..12303
                     /locus_tag="OPV72_003049"
     CDS             11260..12303
                     /locus_tag="OPV72_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011233140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HCR9915281.1"
                     /translation="MSEHDALTSTAPVQEAEQQKNTTHAEAFSFGDPIPVLDRRELLD
                     YVECVQMDRWYEPPVSFDGLARTYRAAVHHSSPIAVKRDILSSTYIPHRLLSQQAFAR
                     FVQDYLVFGNAYLEKRTNRLGGVLSLEPALAKYTRRGLDLDTYWFVQYDLTTQPYEFT
                     QGNIFHLMEPDINQEIYGLPGYLSAIPSTLLNESATLFRRKYYINGSHAGFIMYMTDA
                     AQNQEDVNNIRQAMKSAKGPGNFRNLFMYSPNGKKDGIQIIPLSEVAAKDEFLNIKNV
                     SRDDMMAAHRVPPQMMGIIPNNTGGFGDVEKASRVFVRNELIPLQERIKELNEWLGDE
                     VIRFAKYTLDDIS"
     gene            complement(12352..13047)
                     /locus_tag="OPV72_003050"
     CDS             complement(12352..13047)
                     /locus_tag="OPV72_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000080840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915282.1"
                     /translation="MSQLRLKWMRLKIRTSPEAVFDFIKNTPYSDAIGAGFTKYETIH
                     NGMTATFNKKSVVLEPIADPFGEVLEFERVVFDQISFSIQTLSNKICLLTFYNPPKTV
                     KPFIDFLSQAEGLNVAYGNLTVDLKAFMRVIRENFGVKVFGISKVKVSNLPVTEKTRA
                     CLELNSSGDALHDLKIFVGDSEFKLDKIKAGGFYLDSKISFELTSGASAVVPDEHFSI
                     FNDAISCMEIDKF"
     gene            complement(13067..>13334)
                     /locus_tag="OPV72_003051"
     CDS             complement(13067..>13334)
                     /locus_tag="OPV72_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915283.1"
                     /translation="DLYDRGFYIWKIKWKVKENLADPDIFELEAQFGDPLNCTNFSYL
                     VKGVRKYKANGQYFSKPQKLSGRETERFNKLIENRAYSIIMEIS"
BASE COUNT         2901 a         3948 c         3491 g         2994 t
ORIGIN      
        1 gtatgcgaga agacccgcta catcctttcc actcaaatta gtcagcgtat tgtccagcgg
       61 ttgtttacct gccagtgcat taagcattgt cgtggcaaag ttcgggtcat tccccagcgc
      121 cgccgccagt tcgttcagtg tatccagtgc cgcaggtgca gaacccacca ttgccgcaat
      181 cgccgatttc acaaaagccg tagtggcaat ctgtgtattg ttgaccgact gcgccgccgt
      241 gggggctgtt ggcgttccgg tgagtgccgg actcaacagc ggcgctttca gtgccagcgc
      301 attattaatg gtggtactga atttcggatc attgttaatg gctacggcta tttctttcag
      361 cgtgtccagc gtggctggcg caccattaat aatagccgtc agtgcagcct gaacaaacgc
      421 ggtggtcgca acctgcgtgg tgttattccc cgccgctggc gttggcgctt tgggtgtccc
      481 ggtaaacgta ggactttctt tctgtgcata ctgtgaatgc gggtccggtg cggcaagatg
      541 ttttgccatc aggtcatcca cgtacacctt cagctccagt accttatcat ccacatactt
      601 gcgggttgcc agcactacgg cagggtcgat tttcagggtg atattgtccg tgctgctggt
      661 aatcagcacc atgcgcacgg tctgggtacg cccgctgcct tcagccagtt gcggcttata
      721 gctttccggg cagtttccca cggcaatcaa tgccccggac tcatcaaaca ggcccacttc
      781 acgtatccac caaccgccct cgttttcagg gatcacctgt tcagcaataa tctggctact
      841 gttctgcggg tcgatataaa gcatattcag cgcagcccgg cgtttctcat ttaccagtgc
      901 cgtctgcttt gcgtccggcg ttggcaatac tccgccgcca tcgcccaccg ccatatgggt
      961 aatttttagc ggcacaccga gcgcggcggc gctggcaagt tttgccgcgc caatatccgt
     1021 cagcagggta taaaattttg tgctcatgga ttcactctca ttgtgtcaat aacatggacc
     1081 gccccgcctt catgcgcggt gccaccggaa ataatcgttt cgttgatata cggatagatc
     1141 gtgatttctt cgccaagata gctggcggct cccacccaat gcgggccgct ggtctgcaga
     1201 ttgatggaca tgccgatcat gtggcggcta catggtttgg catcgcttat cagtcgctca
     1261 agttccagat aggtatcttc agtgatgccc tggtcctgca cgccgatatc caggcgaaac
     1321 gtgcccggtg cctctccggt ctgccaccac tcaataatgt ggatcaaaaa gccgaacggc
     1381 tccaccaccc gccgcacggc actggtggtc cctttatgct gatgaatata aaaagcatcc
     1441 ttcaccacct ggcgcttgac gctttctgtc cagccctcgt cccagcgatc cacagagaac
     1501 gcccaggcga gataaggcag gaaactgacc ggacaggttg ccggattcca caagtcacga
     1561 agcggcacct gcagatcaga aatcccgctg caggtttgcg ccaatcggcg ctccagtggt
     1621 gttgaacccg gtggcagcag actattcatc cgttcctccg ttggttacgc tccactgcgt
     1681 acatgatgcc gcctgtgttt tgttcaggac catatccgcc agaggagaag ccagctccac
     1741 acgctgcaca ccctcaacat gcagggcggc aaagatggcg ctacggcgaa tatcccgacc
     1801 aagacgcgtc tgactggcga tgtacttctg caggctggct tttgccgctg ccattaccgg
     1861 ctctgcttcc ggtcccggat agagaaaaat agtggcttcc acccggtacg ggatgatttc
     1921 tgcgctgcga accgtaagac ggtcagccac cgggcggacg ttctcactgt tcagagcttt
     1981 ttccaccacg tccagcaggt ctttttctgc tgttccatcg ccttcgcggc tcaggacagt
     2041 cagcaccacc tctgcaggtg ccggactggt tgcactggca tctgccacac gtccgtccgc
     2101 acttctggcg tgaaattcat aggctcccgt cgggccagca accgacaacc cctcaaacgc
     2161 agcagggatg cgctggcgta gcgcctcatc atcttccatc actgcggcga ccggcggtac
     2221 tgcatcatta tcagcaggca ctacagtcag gcgtttcacg ttgcagttgg ctgccagctg
     2281 ctcaagatca tttcccatcg aataggccac catcaccgcc tgcgcagcct cgttaatacg
     2341 ctggcgcagc aggatttcgc ggtatgtgct ttcctgcagc agcttggtga cgggttcaga
     2401 ttccagcgcc agcgtgcgcc gcaccgcgtc ctgttcatcc acaggataaa gagccacaaa
     2461 agcggccttg cgctcagcca gcagcgtctc aaaatccggc acgtccacta tctgcggcgc
     2521 gggcagccgg gaaaggtcaa tcactgccat tgtctgctcc tgtagttacc gaaagtgaaa
     2581 ccggcgcgcc gttgttgcgc tgcccggtaa gctcaaccac catagagccg tcaaaattgc
     2641 cgttgatggt gatggagtcc agcgtaaggc gcggctccca gcggttcagc gccacataga
     2701 ctgcagacat aatctgcagg cgcagtgccg ggttctgcgg ctggtcaatc agggctgaca
     2761 gtagggagcc atattcccgg cgagcaagac gactgccctg cggcgtcagc agaatatccc
     2821 gcaccgactg gcgcagatgg tcggtatctg caatgacctg cccgtcattc ctgctcatac
     2881 cgatatacaa cgtcataccg gacctcccga tgtatccccg cctgacttaa cgccagtgtg
     2941 accgtgttta tccatcacga ccccgttaga actcattgcg ccgccgccct gggtgacgcc
     3001 gccgttgatc accacctcgc tattaatgcg tgttgtgtca gcctccacca caaactcacc
     3061 ggtttttagg gtgatattgt ccgccgcctc gatcaccatg gatttgatac cccggacatg
     3121 ccacctcccg gtggcgggtt cgtactcaaa ccagcccccg tccgggtact ccgtcacgca
     3181 gccgtccaca gaatccgacg gcggcgcaaa ctgattggag tagatggcgg gcagcacaaa
     3241 agcggtttcc agattgccgc ccatgctcag caccaccacc tgctcatccg gcgacgggca
     3301 ccaccatgta cgggcaccac cggcacgcag cgtcagccag ttaatccagt tagtttcaag
     3361 ctcgcccact ttcacccggc acagccagtt ttcccggtcc acttcggtca cggtgccggt
     3421 gcggatcagg ttggtgataa ggcgcatgat ttcggtcagt tgtgcattca taacgaaagg
     3481 ttgccatcag agggaaaagg gaggcagcgc gggcgcttgt gccagcagtg gcacaaagat
     3541 caccccgcca gccagcgcag cagagtgtca cgggtgatgg tttccacctc atcattcacg
     3601 cccaaaaggc ggcgctctgc gtagcggacc tccgggcctt ttcggctgac gcgatcacgc
     3661 aggccgtaat ggtgaacacg ggcaatgcgc tgcaccttgc catcaaactg cacgctggcg
     3721 gagtccgcac tggcggcggt tttcaggtat tttgtggtgc gaagctttgc aaacatctgg
     3781 cgtttgatac gtcccttctt gctgcgggct gtcaccctgc gcggctcata gccgatgccg
     3841 tcaggattac gctgcagcct gatgttctgc tgctgcgtcc ggcgcaactg ttgcgccagt
     3901 tgccgcatca tacggttgcg tgcggcaggc tccagattcg ccagcagcgc cgtcagccag
     3961 tcatcaacct tctgcagctc atccacgttt caccgtccac atttcttcgg gttcgtccgg
     4021 ctccggcacc gcttcaacgc ttgacacgct gccgtcagtg ctgaccagca cacgctcagt
     4081 cagttgcagg ttcatgctga tatcgcacac atcgtttcgc agaatatcca cttcaaaggt
     4141 gaacagtttt tcgcgcagat ccgggttgtt gatggcgtcc ggctggctgg tactgagcca
     4201 cagcaggact ggggccatca gcagattctg gtcgccgctg aaatcctcga tcaccacgtt
     4261 cagggtgtag cggtattccc atgacatgga actggctcct gttgccacca gtgatccgtt
     4321 atcaacgaaa aggtgcagct tgtccgggtt gtcccggaca taggcaacca ctttattcag
     4381 ggcgctgcgt aaggactgcg gtttgttcac tgtctcgctc ctgacacgca ataattgtgt
     4441 ccactttgtc agcacagacc gcccaggcgg cctcggtttc atccagcacc gcattcagat
     4501 cgccgttact gcgcggcgct gacctttcca ggcggcactg cgtcactctg ggacagccac
     4561 tcacggtaag ctgcacctcc ggcgagggcc gggcggtccc gcaacctgat aatgtcagca
     4621 ggcaaaggag tgtcagccca gcggcgtaaa tcctcgtttt cactttttag ctcctcgatc
     4681 cggcgctggc gacttcgcaa cagtgcggtg gtctgctccg cagccgcata aagccgcgtc
     4741 tgctcccggc tgttggtttc ggtcagaatg gacaggccga tcagctggct gtttttcttc
     4801 gtcagctcct gcgttttgct tttcagcgcc gcgccctgcg tttcgatggt gtggctggca
     4861 ttgtttaacc gccacgactg ccagcccagc gccgcaagtg ccagcgccag cactaccgcc
     4921 agcgcacgca tcaggccgcc atcggctcat gaagctgcga gcgggcaatc tgatacaaaa
     4981 ccagcgtcag caggtaaaac accagggtga tcacccatcc cgaaaacgcc aggcacagaa
     5041 caataagcag cctgatagcc catgtacgca cgggttttac ggggtgcgcc ctgaatttga
     5101 ttaatgccgc cctggcctca tcgcgcgccc gatctccggc gaaccacccg acagcgcaca
     5161 gcgcagcaag cagccaggcg aggaagcatg acacctggac agacgcacca accagaaccg
     5221 gcgcaccgct gcgcggatac agcaggctga ttaccaacag cgcagcccat gccagctgga
     5281 aaaaaacgct catgactttc tttttcattc cgttaggctc cttttaagca ccaggccatt
     5341 tcccgcgcgc ggcggttgtc cagcccctga ttaaacacac ctttgacata tacccagcgc
     5401 ggcagctgat ggcaggcatc cgcccagcgc cgctggttca gcaacttaac cagcgtggag
     5461 ctgcaggcgt tgccggtgcc cacgttgaaa gcaaacgaca ccaccgcgtc atagaccttt
     5521 tgcggcatcg gctgcaccac acatttttcc agcgcccgct ccacgcgcag cacattggtg
     5581 ataagtccct gcgccgcctg ccgttccgtg atggtttttc caggcaccac accggacgta
     5641 ttgccgatcc cgtcagtcca gacgcccgcg ctacactgat aaggctgcag gcggcatccc
     5701 tcgtaatcgg cgatcagttt cagcccctca acggaggtat gaagcgactg aaatccgggc
     5761 agcgtggctg cgatagccag cactgccccg acaaggcagc acttaacgat tgaagtattc
     5821 atattccccc cgcgaaatct tgccgccacg taacaatttg aaagactggt gtttgtagta
     5881 ccagttgata gccagcatca gcacaccaat cagtacgccg ccaaccgttg acgcatcctt
     5941 gagcgacaga tcgcccagcc atgccagcag cacggcaatg cagtaagtga taaaggcgct
     6001 gattcgttca agcgtcataa ttcagtccca tagctggacg gtctgcgccg tggttgacgc
     6061 cgtaatgtcc ggcagctcca cctgcagccc gtgcggtaaa aatgggccgt actcagccag
     6121 ccccggattt gcctgcagaa cctgctcagt gacaccctgc gtgcgcccgt aatgacgcca
     6181 gcaaagcgcg tccaccgtgt catactgatg cgcacgcact ttcatcagat aagctccacc
     6241 gtacagtgcg gtgcatcctg cacccggctg atggcccagc gggcatcacg ccacagatcg
     6301 ccgctggcct ccgccagctc ctcccctcgc ttcacgcctg acgccgtggc gtcatagtcc
     6361 tgataacgct cattaagcac agcgcgcgcc cagcaaaaaa cagcgttgtg gtagtgccgg
     6421 atacgctcgc ttttaccgtc cagcatttct gcgggaacct cagcaagtgt ccgccagccc
     6481 agcatctgct gacggttgcg gaagtcgtac agctcagcgt taacctcaga gatcgccgtc
     6541 agcacgacct gctttaaacg cggctgcgtc accgtgccgt cagtgcgcat cacactgcga
     6601 aattccgaca ggttcacatc aggccagaac ggcgtatttt tgatgacctc cgcctgttcc
     6661 ggtgcctgtt ctggcgcaac aaacttcatg cggcgttctc ctgaataagt gggcggtgga
     6721 cggaattttg atgtggcagt gcctttcgcc atcccgtgcc gcccgtgcgc ggggcacgtt
     6781 cgttagcggc tgtcattgcg cagtctgcgc tccagctgct gcttttcttt tttcacaccg
     6841 cagcggggat caagctgcag cgcatggtta aggtgattca gggcagacgc cgggttgctt
     6901 tcgctcagta cagcaccgat ggctttatgc aggcgcgccc gcgactggtc cggcatatcc
     6961 agatcggtgg tcaggtccag cgtctgcaga agcggatcgg catcaaaacc ggcagcggca
     7021 agcagagcgc tttgcgccgc gtctgccatt tcttctgcca gcacggtctg cacgttacgg
     7081 ttgcccagag gcatcaccca gccatggcgc agcgcatggc gcccgatttc gagcgcaccg
     7141 gcataatcac cggcgtcgat acgccacagc atcacgtaca tcagcacgtc atcctgctgc
     7201 gcacctccgg cagccagcac gccctccgcc caggcggaat atttcggcag cagttccacc
     7261 ttgatttccg cctttttcac cgtggactgg acgcccttga ggcggcggcg gtcttctgcc
     7321 agctgcagca gcatcaggtc atagcccgac gcatggcgaa cactgccgcc ctcacgggcg
     7381 gcctgttcag cctgaatgcg caggcggtgc tgccgtgcgg gactcaggct catgcgttat
     7441 tccccacttt ccggtgcggc aggcgcgctg aaatcaccga tttcgatgtt ttctaccagc
     7501 gccgcgcagc ggtagtcctc gaccacatac gcctcgttga cggattcaaa gttttcaatc
     7561 cggtcgcgtt tcgggttgtc gataactgaa cggcggcggg tgtcttcctg ccagtagatg
     7621 gacaggttat ccagacgggt gatcagcagg gcatttgccg ggaagaaagg cgcgcgcaca
     7681 gcctgcaggc cgcccatgcg tttctggctg atgatcagat cggcggcgat tttctcgctg
     7741 ttgtcctgct ctttgttgac cagcgggaaa tacttgtcag acagcagttc acgtccgcag
     7801 acaacaacca gctcgtcatc atcctgatac tccacatcga tcagctcgtt gacggtatcc
     7861 atcaccaccg cgtcaagatt tacatactta ccacccggac ctacttttac tggttctgca
     7921 gtagtggtgc cgtcttctgc ggttttgctg cccatgacgt gatccggcgc gtcttcgcgg
     7981 attttctgca gccagccttt attgacgtcc tgcagcagcg ggttttcagc acggttggag
     8041 gttttggcgc gcttcacgcc gttaaagccg atcatgatgc ggtccagcgc ctgacgcttg
     8101 acgatggcgt tgcggatacg cacctggaag tcctggaatt tcgcccacag gtccagtttt
     8161 gcgtaggtca gcaccgtatc aaagttggtc tgctcgcatt tgtattccac gtcttccatc
     8221 agcgtcggat cggtaggctc gcgctctttg gtggtggtat cggtggttcc ggcaatggtg
     8281 ctgccaacgc ccagccccag caactgaccg gactgctcag tgaccggcgt gatgttaatc
     8341 agcgtcagga aagcagcaga ctgctggatg tggtcttcca gagtctgctg cacggacggc
     8401 tccacggtga acttgctgga gagttcttca acatccacac cattcaggcg cgccagctgc
     8461 tgcaggtaag cgttaaaggc aaagcgggtt ttctttttca tcgggtttta tgctccatca
     8521 gcaattggtc agggtgcctg ccggtgcgtc accgcccggc gcgcgctggc ggtaatcctt
     8581 gcggctgtct tcgcggctca gttgctgctg tagctcggca aaggcggtct gctgttcctg
     8641 cagggaggac tccagcgcgg aaaggcgctc accgttttca gccagggatt tatcagtgcg
     8701 ctcgctcagg ttctgctgct cggtggcgac aagttccacg gctttatgca catcggagaa
     8761 acgcgcatcg tcggtctgct cttttttggt gaacagcgcg gtgacgctgg caaagaggga
     8821 cggcttttcg tcctgggctt cttccagttc gatcagcgtt tcaaccgctt ccgaaaacag
     8881 gttttcaggg ttctgcttac ggtttgccag cgggttatgt gcggcgctgg cgctgaaagc
     8941 cagcatttcg gtgccaaggc tcgcaggatc gtccgtcgca cccagcccca caaggtaggc
     9001 tttgccggtg tcggcaaact tcgtgctgac ctccatggag gtgaaaagct tctggccttt
     9061 tttcaccagt tccaccaggg cgtcagtggg ttcgatatcg gcataaagtg ccatcttgcc
     9121 cgccagcggg ccgtcctgga tttcttctgc aaccagcccc gtcaccctgc catagcggtt
     9181 aaaagtgctc tccggcagat aagacttgat gtgctcaagg ttaatcagcg cggtatagac
     9241 cgtcgggttg tagctggcag ccatctgtac cagccattca cgctggatct cgcgcccgtc
     9301 agtggtggca ccttccaccc cgatgcggaa acgctttgct ttcactgtca tgagccgtgc
     9361 tccgttagaa ataacttact ggagtcttat gtttgcggtg atggggggag tgagacaacg
     9421 cgctgtattt gtacggtaaa ccacacaaac cgcagccggg gaaagccgcc atccaaggcc
     9481 gtatgtttgg gccatgaaca cgacactgac ccccgcagac ctcgatcccc gtcggcaggc
     9541 catgctgctg tactttcagg gataccgcgt agcccgcatt gctgaaatgc tgggcgaaaa
     9601 agttgcaacc gttcacagct ggaaaaaacg cgacaagtgg ggcgactatg ggccgctgga
     9661 tcagatgcag ctcaccaccg ccgcacgtta ctgccagctc atcatgaagg agcagaaaga
     9721 agggaaagac ttcaaggaaa ttgacctgct ggcgcgccag tcagagcgtc acgcccggat
     9781 cggaaaattt aacgacggcg ggaacgaagc agatttaaac ccgaaagtag ccaaccgtaa
     9841 caaaggtccg cgcaggcagc cggaaaagaa cgttttctcc gacgaacaga tcgaaaagct
     9901 ggaagaagtc ttccacgcct caatgttcga ctatcagcgt cactggtttg aagcaggaaa
     9961 aataaaccgc atccgtaatc tgctcaagtc gcgccagatt ggcgccacgt tttattttgc
    10021 ccgtgaagca ttgattgacg ccctgctgac cggacgcaac cagattttcc tttctgccag
    10081 taaggcacag gcgcacgtct ttaagcagta catcatcgac tttgcaaaag aagttgaggt
    10141 ggagctgaaa ggcgatccta tggtgctacc caatggcgca gcattgtact ttctcggcac
    10201 caacgcccgt acggcgcaga gctaccacgg caacctgtac cttgatgaat atttctggat
    10261 accgaaattc caggagctgc gcaaggttgc ctccggtatg gccattcaca agaaatggcg
    10321 acaaacctac ttttccacgc cgtccagcct gacccacagt gcctatccgt tctggtccgg
    10381 cgcgctgttt aaccggggcc gagccaaagc ggacaaggta gatattgacc tgacccacag
    10441 caaccttgca cgcggcctgc tctgccctga cggacagtac cgccagatcg tcaccgtgga
    10501 ggatgcggtg cgcggcggct gtaacctgtt cgacctcgac cagctgcgca tggagtacag
    10561 cccggacgaa taccagaacc tgctgatgtg cgaatttatt gacgatctgg cgtcagtatt
    10621 cccgctcagc gaactgcagg cgtgcatggt ggacagctgg gaagtctgga ccgattttca
    10681 ggcgctggcg ctgcgcccgt ttggctggcg cgaagtctgg atcggttatg acccggcgaa
    10741 aggtacgcag aacggtgaca gcgcaggttg tgtggttatt gctccgccca ctgtaccggg
    10801 cggaaagttc cgcattctgg agcgtcatca gtggcgtggg atggacttcc gcgcccaggc
    10861 tgacgccatt aaaaagctga cacagcagta caacgtgacc tatatcggca tcgactcgac
    10921 cggcgtcggt cacggtgttt acctgaacgt aaaagacttt tttccagcag tacgagagtt
    10981 tgtctacaac cccaacgtca aaaacgccct ggtgctcaag gcgtacgaca ttatcagcca
    11041 ccgccgtctg gagtttgacg ccgggcatac cgacattgcg cagtccttta tggctatccg
    11101 ccgggccacc accgccagcg gcaaccgccc aacctatgaa gccagccgca gcgaagaagc
    11161 cagccacgca gatttggcct gggcaacgat gcacgcactg tttaacgaac cgctgcaggg
    11221 cgaagccgcc aataccagca atattgtgga gattttttga tgagtgaaca cgacgccctg
    11281 accagcaccg cgccagtgca ggaggccgaa cagcagaaga atacaactca cgccgaagcg
    11341 ttcagctttg gcgatccgat cccggtactg gaccgccgcg aactgctgga ctatgtggaa
    11401 tgcgtacaga tggacagatg gtatgagccg ccagtaagct ttgacgggct ggcgcgaacc
    11461 taccgcgccg ctgtgcatca cagctcaccg atagcggtta agcgtgacat tctcagcagt
    11521 acgtacatcc cgcaccgcct gctcagccag caggcttttg cccgtttcgt ccaagattat
    11581 ctggtgttcg gtaacgccta tctggaaaag cgcaccaacc ggctcggcgg cgttctctca
    11641 ctggagccag cactggcgaa gtacacacgc cgtggcttgg acctcgacac ctactggttt
    11701 gtgcagtacg acctgaccac gcagccctat gaatttacac agggcaacat ctttcacctt
    11761 atggagccgg atattaacca agagatttac gggctgcccg gctatctctc cgccattccg
    11821 tcaaccctgc tcaacgagtc cgcaacgctg ttccgccgga agtattacat caacggcagc
    11881 catgcggggt tcatcatgta tatgaccgat gcagcacaga atcaggagga cgtgaacaat
    11941 atccgccagg caatgaaaag cgccaaaggg ccgggcaact tccgcaacct gtttatgtac
    12001 tcgcccaatg gtaaaaagga cggcatccag atcatcccgt tgtcggaagt tgcggcaaag
    12061 gatgagtttc ttaacatcaa gaacgttagc cgcgatgaca tgatggcagc gcaccgcgtg
    12121 ccaccgcaga tgatgggcat catccccaac aataccggcg gctttggtga tgtggaaaag
    12181 gccagccgcg tgtttgtacg aaatgaatta ataccccttc aagaaaggat taaagaactc
    12241 aatgaatggt taggggatga agtcattaga tttgcgaaat atacactcga cgacataagc
    12301 taattttatt ataaaagatg gtgccatcat ataacgatga caccatcgcc cctaaaattt
    12361 atcaatttcc atacatgaaa tagcatcatt gaaaatcgaa aaatgctcat caggaaccac
    12421 tgcagaagcc ccactggtta attcaaaact aatctttgaa tcaaggtaaa accctcctgc
    12481 ttttatttta tcgagcttga attcactatc cccaacaaaa atcttcaaat catgcaaagc
    12541 atcgccgcta gaattcaatt ccaaacatgc tcttgttttt tcagtaacag gaagatttga
    12601 caccttcact ttggaaatgc caaacacctt tacgccgaaa ttttctcgaa tgaccctcat
    12661 gaaagcttta agatctacgg ttaaattccc ataagcaaca tttaaccctt cggcctgaga
    12721 caaaaaatcg ataaaaggtt taactgtttt tggaggattg taaaaagtta acaaacatat
    12781 cttattgctg agggtttgga tagaaaaact aatctgatca aatacaaccc tttcgaattc
    12841 cagcacctca ccaaatggat cggcaatcgg ctctaaaaca acagattttt tattgaaagt
    12901 tgcagtcata ccattatgaa tggtttcata cttagtaaaa ccagcaccaa tagcatcaga
    12961 ataaggcgtg tttttgataa aatcaaagac agcttcaggg ctggtcctga ttttcaatct
    13021 catccacttc aatcttaatt gtgacatagc cactccttat gatgtattag ctgatttcca
    13081 ttataataga ataagctcta ttttcaatta atttattgaa tcgctcagtt tctctaccag
    13141 agagtttttg cggcttactg aaatattgtc cgtttgcctt atattttctg actcccttaa
    13201 ctaaatatga gaaattagta caattgagag gatcaccaaa ttgggcctca agctcaaata
    13261 tatctggatc tgccaagttc tccttgacct tccattttat tttccagata tagaatcctc
    13321 tatcataaag atca
//
LOCUS       DAJVBX010000127        13197 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.127, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000127 DAJVBX010000000
VERSION     DAJVBX010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 13197)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13197)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13197
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.127"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..180
                     /locus_tag="OPV72_003052"
     CDS             <1..180
                     /locus_tag="OPV72_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS biosynthesis protein WbpP"
                     /protein_id="HCR9915284.1"
                     /translation="SRAEPIYKDFRDGDVKHSQADITKIKTFLSYEPEFDIKEGLKQT
                     LKWYIDKHSTLYSSV"
     gene            204..2699
                     /gene="tviD"
                     /locus_tag="OPV72_003053"
     CDS             204..2699
                     /gene="tviD"
                     /locus_tag="OPV72_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010989299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Vi polysaccharide biosynthesis protein TviD"
                     /protein_id="HCR9915285.1"
                     /translation="MNLMKSSGMFTLTAIGSCRIVSPVKRAQPYFNFQANFKRIYGFT
                     HTSSEALQQIRFILGLIDIPEKVRPFIFRPNVNYSNTDVHSRSDFYIIEISSQKKIMA
                     YGFCLQINYLTRHFYEFFSQTERACIYWSLATQGNRHKLLAYLKDDPCFAGMSEDDRA
                     LLSNINVEQMDEHAIEQDMMEIVQLLGRDRVMFMTHVDAVTRAGTVILSRSRLIKNVD
                     TIAARMDIPCVNPTNLMEKWGQKRALEKNGDDLTHYTDMFGDAIVAAIFKGVINNTNH
                     HLDEGRQEKQDQIREITLSITKQLADGDIIAASQQLFAALRNQQQDPVLIQLRSVIFS
                     HLGYYEQAYQDISDVEKIIGTTDSTLRCRLRSLHGLARWREALSTAEMMLSNEIEDEE
                     VLTVAAGSADALQLFDKSYHYWKRVLLLNPETQSGWVNFLSSTQYFNDGNAFSEAFHA
                     GIQSQRLNDTFMETALSLAIKFSDELIFMHALEQLLRHESEFALTVLSTIHDTGLVIR
                     TAFCIKNMSYHQALRTSYKDKIHDVFEAWNNTALSLHSVDDFVSLSTSLAYSYSAFMV
                     YPHSRISRFNNEVKMAWRDKLREMYEREDYENILAGAKIVWPLLKFDPVGTVYCARTL
                     VNLGAWKDACTLAHMTLIRNSNITSLQSIMLRSIRHINNIPFLIDLIANVMSITLSFQ
                     NASMNKLFEKECRNVATRALKYVRQKKTEGRLDEALSVLISLKRIEPDVSRLMREYKQ
                     IIRLFNESRKDGGSTITSYEHLDYAKKLLVFDSENAYALKYAALNAMHLRDYTQALQY
                     WQRLEKVNGPTEPVTRQISTCITALQKNTSGKS"
     gene            2699..4435
                     /gene="tviE"
                     /locus_tag="OPV72_003054"
     CDS             2699..4435
                     /gene="tviE"
                     /locus_tag="OPV72_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000632615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Vi polysaccharide biosynthesis
                     glycosyltransferase TviE"
                     /protein_id="HCR9915286.1"
                     /translation="MITQEEKLAALGKTCLTLKQEKKLAQAVALIDSELPTEALTSLA
                     MLKKAEFLHDVNETERAYALYETLIAQNNDEARYEYARRLYNTGLAKDAQLILKKVSN
                     GVQKKYNNYLGKINKICDLLERLEGKAIPVGTNTCIIAMKHAILFYRNRQPRQLPVGS
                     FGRLALCTGSLGSGGAERQISRLAIEIARKYRQKGKIGGLKVEEPVELIIRSLTPELR
                     QDFFLKEVLEEQVEVLEIAKITGNLFDDATIESPELRLLLSHLPPVCKYGIKHLVPHL
                     CERKLDYLSVWQDSACLMIALAALIAGVPRIQLGLRGLPPVVRKRLFKPEYEPLYQAL
                     AVVPGVDFMSNNHCVTRHYADWLKLEAKHFQVVYNGVLPPSTEPSSEVPHKIWQQFTQ
                     KTQDADTTIGGVFRFVGDKNPFAWIDFAARYLQHHPATRFVLVGDGDLRAEAQKRAEQ
                     LGILERILFVGASRDVGYWLQKMNVFILFSRYEGLPNVLIEAQMVGVPVISTPAGGSA
                     ECFIEGVSGFILDDAQTVNLDQACRYAEKLVNLWRSRTGICQQTQSFLQERFTVEHMV
                     GTFVKTIASQPR"
     gene            4480..5547
                     /gene="vexA"
                     /locus_tag="OPV72_003055"
     CDS             4480..5547
                     /gene="vexA"
                     /locus_tag="OPV72_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Vi polysaccharide ABC transporter protein VexA"
                     /protein_id="HCR9915287.1"
                     /translation="MKKIIILLTTFFLLSGCTIPRAVFKSSLINQDDPRYNLVEVTPT
                     LKLSAPDTVPKTIVDPVFAANNWHWTSLAKGDVLHITILSSGGAGYLSNNASGDRADF
                     ENILVTDSNTVQVPYAGTIPVSGLDVTQLADEIKKRLSRVVLNPQVIVTLTARTGAMV
                     TVEGSGKTGRYPLEQSMNRLSHLLATAVAVENTSTDMMEVHVTRQQHYFTARLSDIYQ
                     YPGLDIALQPDDRITLRQVTEYVNVLGAAGVQGKHALVQRHSSVVDALALAKGLNDNL
                     ADPQAIFLYKHNEAEQAKQQMRKLNIYHVDMSQPNSVFLAQAIRVDNGDVIYISNASL
                     TDFAKVKAAFDSFLTRGTNSF"
     gene            5557..6351
                     /gene="vexB"
                     /locus_tag="OPV72_003056"
     CDS             5557..6351
                     /gene="vexB"
                     /locus_tag="OPV72_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001023498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Vi polysaccharide ABC transporter inner membrane
                     protein VexB"
                     /protein_id="HCR9915288.1"
                     /translation="MNILKNNSYYFMKLITVCELIILLMSRDIKTRYNGNLLNYMMVL
                     AVPLVWISITVISFQYLNRSVPISTDDISFVIAGILPYLLFRYTITATMRTHSFSTSL
                     AVVSQVKKRHVIFSLAAIEFVNAVIIYIIISLINFLIFSRWEAQKPFLIFEGMVIAWL
                     LGLSFGYFCDALSERFPLVYKAVPVMLRPMFLISAVFYTANELPYSLLSIFSWNPLLH
                     ANEIVREGMFEGYHSLYLEPFYPLAFSATLFLAGLIFHLICDTENH"
     gene            6377..7072
                     /gene="vexC"
                     /locus_tag="OPV72_003057"
     CDS             6377..7072
                     /gene="vexC"
                     /locus_tag="OPV72_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000467404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Vi polysaccharide ABC transporter ATP-binding
                     protein VexC"
                     /protein_id="HCR9915289.1"
                     /translation="MFGLLGCTRYFESDKGPRVVLDKTDFVMGYHEHIGILAAPGSGK
                     TTLTRLLCGLDAPDEGDFIGLRGDALPLGANSFILPGLTGEENARMMASLYGLDGDEF
                     SHFCYQLTQLEQCYTDRVSEYSVTMKTHLAFAINLLLPCRLYIADGKLYTGDNATQLR
                     MQAALACQLQQKGLIVLTHNPRLIKEHCHAFGVLLHGKITMCEDLAQATALFEQYQSN
                     QATIQTEDYSFDI"
     gene            7095..8399
                     /gene="vexD"
                     /locus_tag="OPV72_003058"
     CDS             7095..8399
                     /gene="vexD"
                     /locus_tag="OPV72_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000431675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Vi polysaccharide ABC transporter inner membrane
                     protein VexD"
                     /protein_id="HCR9915290.1"
                     /translation="MENSERIKKWKEERAKVAQESRASRLQQKEDERALRQTEKSADA
                     KSHHNPDAGWSATDADSVRRASLVIKERRVQQAKQSLRRLFLYIALPLLVIMLMSWIL
                     TSHFYSADATFIVQTDASQDNFSGTSFFGAGNKMSEGFQVREFILSKEMMDRMEKELG
                     FLSYFAQDDIALFSRFHAPLGINDDPYRYYLSKVSVAVDIQQGMLRLNVKARSAKQAE
                     FFAQRILSFAEQHVNTVSARMQKERILWLENDVKSAQENLGAARLELLKIQHIQKDID
                     PKETITAIYQLIAGFETQLAEAKAEYAQLMVNGLDQNPLIPRLSAKIKVLEKQIGEQR
                     NRLSNKLGSQGSSESLSLFEDLRLQSEIAKARWESALQTLQQGKLQALRERQYLLIIS
                     QPMAESDTTRYADGTKWLLFFVLLGITYLVTSLLITIRRMRE"
     gene            8419..10389
                     /gene="vexE"
                     /locus_tag="OPV72_003059"
     CDS             8419..10389
                     /gene="vexE"
                     /locus_tag="OPV72_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000052242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Vi polysaccharide transport protein VexE"
                     /protein_id="HCR9915291.1"
                     /translation="MSLHSTFKKISPTTLLKQEDWEGLCLYFSQHPEKVRDSAGNEQN
                     IILFAIACLRKDETDVGLTLLSDRVLTAKNGRDLLRRWVISPLASSQPDAVLQVVNKL
                     LAVNVCQPEDVLLVASVLLKSKQYATVADLAEQAWLAFSGNSQIFALHLRTLVLMDKE
                     LQAISLARTQAQEVPPRGDMIATCLSFLNKSRLPEDHDLARALLPFFALERQESAGLA
                     VDTLCAVGKYQEAIQTGESALARGLDGAALRRSLGLAYYQSGRSREAKLQAAEHWRHA
                     LQFNSDNVRIVTLYADALIRTGQNEKAIPLLQQSLATHPDLPYVRAMYARALRQVGQY
                     TAASDEFVQLAREKGVTSKWNRYAAAALLQAGKTSEAESVFEHYIQARASHLPQSFEE
                     GLLALDGQISAVNLPPERLDWAWEVAGRQSGIERDEWERRAKWGYLADNFLLDWLECR
                     GEQADEPMYRLADISHVEQFFQRLQLDQRGCIIVSAHLGAMYAGPMILSLLEMNSKWV
                     ASTPGVLKGGYGERLISVSDKSEADVVRACMQTLHSGQSLVVAIDGALNLSAPTIDFF
                     GQQITYSTFCSRLAWKMHLPTVFSVPIWKNRHIHFVLERMVDPLKFESQLSFTERWKE
                     NYLQCVTRILQSDPENLRLSGGIWRNIIRRDS"
     gene            complement(10691..11437)
                     /locus_tag="OPV72_003060"
     CDS             complement(10691..11437)
                     /locus_tag="OPV72_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCR9915292.1"
                     /translation="MDIPRIFTISESEHRIHNPFTPEKYATLGRVLRMKPGMSVLDLG
                     SGSGEMLCTWARDYGITGTGIDMSPLFTAQAKLRAEELGVSERVHFVHNDAAGYVADE
                     QCDIAACVGATWIAGGVAGTMNLLAMSLKPGGIMLIGEPYWRQVPPTEEIAQACGVSS
                     VADFLTLQGLVASFDERGYDLVEMVLADQEGWDRYEAAKWLTMRRWLEDNPDDDFVQE
                     VRKELTVAPKRHVNYTREYLGWGVFALMAR"
     gene            complement(11437..12327)
                     /locus_tag="OPV72_003061"
     CDS             complement(11437..12327)
                     /locus_tag="OPV72_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001681808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HCR9915293.1"
                     /translation="MDISTLISSSGRLQLSAAESKIPWEELAFSQRMLENHLSQDHDW
                     ASRRQIVIEQQVGWIARQLLVGARILDIGCGPGLYTHLLAERGYCCTGVDFSPASIEW
                     ARQQAQTAGLSIDYIRQDIRTYWPETQFEFIMMTFGELNVFSATDAQTLISRCARWLV
                     PGGRLFVEVHTFDEVKRQGMAPASWQRCPHGLFLAASHLLLTENAWDEETQTSSTQFW
                     AIDENGRISRFGSQMTAWRDDEYASLLGNAGFKILSHPDSSEWPVSETFEGKLFALLA
                     EKSKSPEGRSLNTQLKKGVN"
     gene            complement(12338..12595)
                     /locus_tag="OPV72_003062"
     CDS             complement(12338..12595)
                     /locus_tag="OPV72_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjhX family toxin"
                     /protein_id="HCR9915294.1"
                     /translation="MNLSRQEQRTLHVLAKGGRIVHVRDASGRVTSVECYSREGLLLA
                     DCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRSQPDNR"
     gene            complement(12897..13007)
                     /locus_tag="OPV72_003063"
                     /pseudo
     CDS             complement(12897..13007)
                     /locus_tag="OPV72_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310150.1"
                     /note="with lsrACD is involved in the transport of
                     autoinducer 2 into the cell; incomplete; partial in the
                     middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer 2 ABC transporter substrate-binding
                     protein"
BASE COUNT         3445 a         2973 c         3211 g         3568 t
ORIGIN      
        1 agtagagctg aaccaattta taaagatttt cgtgacggtg acgttaagca tagccaggca
       61 gatattacca aaataaaaac atttctttca tatgagcctg aatttgatat caaagaagga
      121 cttaagcaga ctctaaaatg gtatatcgat aaacattcta ctttgtattc ctcggtataa
      181 ctactcactt tcctttcacg tggatgaatt taatgaaatc gtcagggatg tttacgctta
      241 cagccattgg cagttgccgt attgtgagtc cggtaaaacg agctcagcct tattttaatt
      301 ttcaggcaaa ctttaagaga atatatggtt ttacgcatac gagcagcgag gcattacagc
      361 agattcggtt tattttgggc ttgatagaca ttcctgaaaa ggtccgacca tttattttta
      421 gacctaatgt aaactattca aacaccgacg tacatagtcg ttctgatttc tatatcattg
      481 agatttcaag tcagaagaag attatggcct atgggttctg cttacaaata aattatttaa
      541 ctcgtcattt ctatgaattt tttagccaaa cagagcgggc gtgcatatac tggtcgttgg
      601 ccacgcaagg aaatcgacac aaactgctgg cctatctcaa agacgatccc tgttttgccg
      661 gaatgtcgga agacgatcgt gccttattaa gcaatatcaa tgtcgagcag atggatgagc
      721 atgctatcga acaggatatg atggaaatcg ttcagcttct tggtcgcgat cgcgttatgt
      781 ttatgacaca tgttgatgcc gtgactcgtg ctggaaccgt cattctatcc cgtagtcggt
      841 tgattaaaaa tgtcgacacc atcgccgcca ggatggatat tccctgcgtt aacccgacaa
      901 atttgatgga aaagtggggg cagaaacgag ccctggaaaa aaatggcgac gatcttactc
      961 attataccga tatgtttggt gacgcgatcg ttgcggctat ttttaaggga gtgatcaata
     1021 atactaatca tcatcttgat gaggggcgac aagagaaaca ggaccaaata cgtgagatta
     1081 ccttatcgat cactaagcag cttgcagatg gcgacattat tgctgcatca caacaacttt
     1141 ttgccgcatt aagaaatcag cagcaagatc ccgttctaat ccaacttcgg tccgtaatct
     1201 tcagccattt aggttattat gaacaggctt atcaggatat tagtgatgtt gagaaaatta
     1261 tcggtacgac tgacagtaca ttacgttgtc ggctgaggtc tctacatgga ttagcgcgtt
     1321 ggcgggaagc cttatcgacg gcagagatga tgctttccaa tgaaattgaa gatgaagaag
     1381 tccttaccgt tgccgccggc tcagccgatg ctttacagct gtttgataag tcatatcatt
     1441 attggaaacg tgtactatta ttgaatcctg aaactcaaag cggatgggtt aatttcctga
     1501 gcagcacgca atatttcaat gatggcaacg cattctctga agctttccat gccggcattc
     1561 aatcgcagcg cctaaatgat acgtttatgg aaacggcgtt atctttggca atcaaattca
     1621 gtgatgaatt gattttcatg catgcgctcg agcagctact ccgccatgag tcagaatttg
     1681 cgctgacggt attgtcgacg attcatgata ccggtctcgt tatccgcaca gctttctgca
     1741 tcaagaatat gagctatcat caagcgcttc gcacctcgta taaagataaa atccacgacg
     1801 tttttgaggc atggaacaat accgcgctgt cgctacattc ggttgatgat tttgtctcac
     1861 tgagtacttc gctagcctat agctactctg catttatggt ttatccccat tcacgtattt
     1921 ctcgctttaa taatgaagtt aaaatggcat ggcgcgataa attaagagaa atgtatgagc
     1981 gtgaggatta tgaaaatatc ctggcagggg cgaaaatagt gtggccactt ctgaagtttg
     2041 atcccgttgg caccgtatat tgtgcaagaa cgctggtgaa tcttggtgcc tggaaagacg
     2101 cgtgcacgtt ggcccacatg accttgattc gtaactcgaa cattaccagc ctgcagtcga
     2161 ttatgttacg cagcatacgt catattaaca acattccgtt cctcattgat ttgattgcta
     2221 acgtcatgag cattactcta tcattccaga atgcctcaat gaacaagttg tttgagaaag
     2281 agtgtcgcaa tgttgcaacc agagccctta aatatgtacg ccagaagaaa actgaagggc
     2341 gtctggatga agcattgtct gtattgatta gcctgaaacg aattgagcct gatgtttctc
     2401 gtctgatgcg tgaatataag caaattatca gattatttaa tgagtcacgg aaggatggcg
     2461 gtagcactat cacgtcttat gaacatctag actatgcgaa aaaattactc gtttttgata
     2521 gcgaaaatgc ctatgccttg aaatatgccg cattaaatgc aatgcattta cgcgactaca
     2581 cgcaggcttt gcagtattgg cagcgactgg agaaagtgaa tggaccaacg gagccggtga
     2641 caaggcagat ctcgacctgc ataaccgcat tacaaaaaaa tacatcaggg aagtcgtaat
     2701 gattacgcag gaagaaaagt tagctgcact aggaaaaacg tgtttaacat taaaacaaga
     2761 gaagaagctt gcgcaagctg ttgcgttaat tgacagtgaa ttaccgactg aggctttaac
     2821 ttcattagcg atgctaaaaa aagcagagtt tcttcatgat gtcaatgaaa cggagcgtgc
     2881 atacgcgctc tacgaaacgc tgattgcaca aaacaatgat gaagcacgtt atgagtatgc
     2941 acgtcgttta tataatacgg ggctagccaa agatgctcag ctaattctta aaaaggttag
     3001 caatggtgtg cagaaaaaat ataacaatta tttaggcaaa ataaataaga tctgtgattt
     3061 gcttgaacgc cttgaaggga aagcgatccc tgtggggacc aacacctgta ttattgcaat
     3121 gaagcatgcc atcttgttct atagaaatcg tcaacccagg cagcttcccg tcgggtcttt
     3181 cggtcgtctt gcgctctgta ctggctcgct aggtagcggt ggtgcagagc gtcagatttc
     3241 caggctggct atcgaaatcg ccagaaaata tcggcaaaag gggaaaattg gcggcctgaa
     3301 agtagaagaa ccggtagaac taattattcg ctccctgaca ccggaactca ggcaagactt
     3361 tttcctgaaa gaagtgctgg aagaacaggt cgaggttctt gaaatcgcga agattaccgg
     3421 aaacttgttt gacgatgcga caatagaatc tccagagttg cgcttattgc tatcgcatct
     3481 accgccggtg tgtaaatacg gcatcaagca tctggtcccc catttatgcg agcgcaagct
     3541 ggattatctc tccgtttggc aggatagcgc ttgtctgatg attgcgcttg cagcattgat
     3601 tgctggcgtg cccagaattc aactgggatt acgtgggtta ccgccggtgg ttagaaagcg
     3661 tctgttcaag ccggaatatg agcctctcta ccaggcgctg gcggtcgtgc ctggcgttga
     3721 ttttatgagt aacaaccatt gtgtgactcg ccattatgcc gactggctga agttggaggc
     3781 gaagcacttc caggttgtat ataacggcgt cttaccgcca tctactgaac cctcttctga
     3841 ggtgccacat aaaatctggc agcagtttac gcaaaaaacc caggatgcgg acacgactat
     3901 tggtggcgtt ttccgctttg taggcgataa gaaccctttt gcatggattg attttgcagc
     3961 acgctattta caacaccacc ccgccacgcg ctttgtgctg gtaggcgatg gtgatttacg
     4021 cgctgaagcg cagaaacgcg ccgaacagtt agggattctg gagagaatac tattcgttgg
     4081 cgcctcgcgt gacgtagggt attggctgca aaaaatgaat gtattcattt tgttttcgcg
     4141 ttatgaaggg ctacctaatg tgcttattga agcacaaatg gtcggggtgc cggtgatttc
     4201 aacccctgca ggtggatcgg cagaatgctt tattgagggt gtttcgggtt tcattcttga
     4261 tgatgcacag acggtcaatc ttgaccaggc ttgccgctat gcagaaaagt tggtcaattt
     4321 atggcgcagc agaaccggta tttgccaaca gacgcagtca tttttacaag aacgcttcac
     4381 cgtggaacat atggtgggaa cgtttgtaaa aaccattgcc tctcagcctc gttaattaat
     4441 gggcatcatt tttcagctat ttcatttata aaataagtta tgaaaaaaat catcatatta
     4501 ctaacgacat ttttcctgct ttcgggatgc actattccca gggcggtatt taaatccagc
     4561 cttattaatc aggacgatcc tcgttataat ctggtcgaag tcacgccgac attaaaacta
     4621 agcgctcccg atactgtgcc gaaaactatt gtcgatccgg tttttgccgc aaataactgg
     4681 cactggacat ctttggctaa aggcgatgtg ctgcatatca ctattttatc ctcgggcggg
     4741 gctggatatt tatccaataa cgcgagcggc gaccgtgcgg attttgaaaa tattcttgtg
     4801 actgacagta ataccgttca ggtgccttat gccgggacaa tcccggtttc tggattggat
     4861 gtgacgcaac tggctgatga gatcaaaaag cgactttcgc gcgttgtcct gaatcctcag
     4921 gtgattgtga cacttaccgc ccgcaccgga gccatggtga cggtcgaggg cagcgggaaa
     4981 acgggtcgat accctctcga acagagtatg aatcgtctga gtcatctttt ggcaacggca
     5041 gtggcagtag aaaataccag cacagatatg atggaagttc acgtgacgcg ccagcagcat
     5101 tatttcactg cgcgactgtc agatatttat cagtatcccg gattggatat tgccttacag
     5161 ccggatgacc gtatcactct gcgtcaagtg accgagtatg ttaatgtgct cggcgcagca
     5221 ggtgttcagg ggaaacatgc tctggttcag cgtcattcca gcgtcgtgga tgctttggcg
     5281 ctcgcgaaag gattaaatga caatcttgcc gatccgcaag cgatttttct gtacaagcat
     5341 aacgaagcgg aacaggcgaa acagcagatg cgtaagctga atatctatca tgtcgatatg
     5401 agccaaccta actcggtgtt tttagcgcag gccatacgag tggacaacgg cgatgttatc
     5461 tatatctcga acgcctcttt gactgatttc gctaaggtga aagccgcatt cgatagcttt
     5521 ttgacccgcg gcactaattc tttctaatgt cgccatatga atattttgaa aaataattct
     5581 tattatttta tgaaactcat taccgtctgt gagttaatta ttttattgat gtcacgcgat
     5641 atcaaaacac gctataacgg taatttacta aactatatga tggtgctggc cgtaccactg
     5701 gtatggatat ccattaccgt tatttctttt caatatttaa atcgctcggt gccaatatcc
     5761 actgacgata tcagttttgt tattgcaggg atattaccgt atctgttatt tcgttatacc
     5821 attaccgcaa ccatgcgaac ccattcattc tctacatcgt tagcggttgt ctcgcaggtt
     5881 aagaaaagac atgtgatttt ttctcttgcc gcaatcgaat ttgttaatgc agttatcatt
     5941 tatattatta tttcattaat taactttctt atattctccc gttgggaggc ccaaaaaccg
     6001 ttcctgattt ttgaagggat ggttatcgca tggcttctgg ggttatcgtt tggttacttt
     6061 tgtgacgcac tgtctgaacg gtttccgctg gtctacaaag ctgttcctgt gatgctaaga
     6121 ccgatgtttt tgatttcggc tgtcttttat acggcgaatg aattgcctta ttcattatta
     6181 agcatattca gctggaaccc tctactacat gctaatgaga tagtcagaga aggtatgttt
     6241 gaggggtatc actccttgta ccttgaacct ttttaccctc tggcattttc cgcaacgtta
     6301 ttcctcgcgg gcctcatttt tcacctgatt tgtgacactg aaaatcactg actttagctt
     6361 caggagagac gcattcgtgt tcggtttatt aggttgtaca cgctattttg agtctgataa
     6421 gggcccgcgg gtggtccttg ataaaacaga ttttgtcatg ggctaccatg agcatatcgg
     6481 tattctggcg gctcctggtt caggcaaaac gacgctaacc aggttgctgt gtggcctgga
     6541 tgctcctgat gagggggatt ttattgggct acggggtgat gcgctcccac tgggggcaaa
     6601 ctcttttatt ctgccagggt taaccggtga ggagaatgcg cgaatgatgg caagtctata
     6661 tggcctggat ggcgatgagt tttcacattt ctgttatcaa ttgacccagc ttgaacagtg
     6721 ctataccgac agggtgagtg aatattctgt cacgatgaaa acgcatctgg catttgccat
     6781 taatttactg cttccctgcc gcctttatat tgctgatggc aagctgtaca ccggggataa
     6841 tgccacacag ttgcgtatgc aggcggcgct agcttgtcag ctgcaacaga aagggttgat
     6901 tgtgctaacg cacaaccctc ggcttattaa agaacactgt catgcgtttg gcgtactgct
     6961 gcatggaaaa attacaatgt gtgaagattt agcgcaggca actgcgcttt ttgaacaata
     7021 tcagtcaaat caggcgacga ttcaaactga agattattcc tttgatatat aattagtaaa
     7081 tatacggata gagtgtggaa aattcagaac gtattaaaaa atggaaagaa gaaagagcga
     7141 aggtagcaca agaaagccga gcctcgcggc tacaacaaaa agaggatgaa cgcgcccttc
     7201 gccagacgga aaaatcggcc gatgcaaaaa gtcatcataa cccagacgcc gggtggtctg
     7261 cgacggatgc tgattctgtc cgtagagcgt cattagttat taaagagcga cgtgttcagc
     7321 aagccaagca atcgctacgt cggctctttc tttatattgc tttgccgctg ctggttatta
     7381 tgcttatgtc gtggatttta acatcgcatt tttatagtgc ggatgccacc tttattgtgc
     7441 aaactgatgc cagccaggat aatttttctg gaacatcttt ctttggtgca ggcaataaga
     7501 tgtcggaggg ctttcaggtt cgcgagttta tactttcgaa agaaatgatg gatcggatgg
     7561 aaaaagagct cggtttttta tcttatttcg cgcaagacga tatcgcatta ttttcccgct
     7621 tccacgcgcc gctgggtatt aatgatgatc cttatcgtta ctatttatca aaagtctcgg
     7681 ttgctgtcga tattcaacag ggcatgctgc gtttaaacgt gaaggcacgg agtgcgaaac
     7741 aggctgagtt ttttgcccag cgcattctgt cttttgctga acagcacgtt aataccgttt
     7801 cagcgcggat gcagaaggaa cggattttgt ggctggaaaa tgatgttaaa tcggcccaag
     7861 agaatctggg ggcagctcga cttgaattgc taaaaataca gcatatacaa aaagatattg
     7921 acccgaagga aaccataacc gctatttatc aattaattgc tggctttgaa acgcagttgg
     7981 cggaggcgaa agcggaatac gcgcaattaa tggtgaatgg tttggatcag aaccccctta
     8041 ttcctcgcct gtcggccaaa atcaaggtac tggaaaagca gatcggcgaa caacgtaacc
     8101 gcttgtcaaa taagttaggg tcgcaaggct cttcagaaag cctgtcctta tttgaagatc
     8161 ttcgcctgca gagcgagatc gccaaagcac gctgggaatc tgccttacag accttacagc
     8221 aagggaagct tcaagctcta cgtgagagac agtatttgct gatcatttct caaccgatgg
     8281 ctgagtctga caccactcgc tatgccgatg gaacaaagtg gttactgttc ttcgtgttgc
     8341 tgggcatcac gtacctggtg acttctctcc tgataaccat caggcggatg cgtgaataag
     8401 gctgagtaag gaaatataat gagcttgcac tctacattta aaaaaatatc gccaaccacc
     8461 ctactcaaac aagaggattg ggaggggcta tgcctctatt tcagtcagca tcccgaaaaa
     8521 gtgcgagata gtgctggaaa tgagcaaaac attattctct tcgctatcgc gtgtttgcgt
     8581 aaagatgaaa cagatgtcgg gctgactttg ttgtctgacc gtgtgctgac ggcaaagaat
     8641 ggccgtgatt tattacgacg ctgggttatt tcgccactgg catcatctca accggacgct
     8701 gtactacagg tagttaataa actgctggcg gtgaatgtgt gccagccgga ggatgtcctg
     8761 ctggtcgcga gcgtgctgct taagagtaaa caatatgcga ctgttgctga cttagccgag
     8821 caggcatggc tcgctttttc gggaaatagc caaatttttg ccctccattt gcgcacactg
     8881 gtactgatgg ataaagagtt acaggcaatc tcgttggcca gaacacaggc gcaggaagtt
     8941 cccccacggg gagatatgat tgcgacctgc ctcagtttct taaataaaag ccgcctacca
     9001 gaagatcatg acctggcccg cgcattgctc cctttcttcg cgttagaaag gcaggagtcg
     9061 gcggggctgg cggttgatac gctgtgcgct gtcggtaaat atcaggaagc cattcagaca
     9121 ggggaatccg cattagcccg tgggttggat ggtgcagcac tgcgtcgtag cctggggctt
     9181 gcttactatc aatccggtcg cagtcgggaa gcgaagcttc aggccgctga gcattggcgt
     9241 catgccctgc aatttaactc tgataatgta cgtatcgtga ccctgtatgc cgatgcctta
     9301 atcagaacgg gtcagaatga gaaagccatt ccgttactgc agcagtcgct cgcgactcat
     9361 cctgatcttc cttatgtcag agcaatgtat gcccgagcac tgcgccaggt tgggcaatac
     9421 actgctgcca gcgatgagtt tgtacaactg gcaagggaaa aaggggtgac gagtaaatgg
     9481 aaccgttatg ccgcggcggc attgttacag gcggggaaaa caagcgaagc ggaaagcgtc
     9541 tttgagcact atattcaggc cagagcaagt catctgcctc aatcattcga agaggggctg
     9601 ctggcgcttg atgggcaaat atctgccgtt aatctaccgc ctgagcgcct tgactgggca
     9661 tgggaagttg ccggcagaca gtccggtatc gagcgcgacg aatgggaacg ccgggcgaag
     9721 tggggctatc ttgctgataa ttttctcctc gactggcttg aatgtcgggg agagcaggct
     9781 gatgaaccta tgtaccgatt ggccgacata tcgcatgtcg aacagttttt ccaacggcta
     9841 caactcgatc agagaggctg cattattgta tcggctcatc tgggcgcaat gtatgccggg
     9901 ccgatgatcc tgtccttact ggagatgaac agcaaatggg tggcttccac tcctggcgtg
     9961 ctcaaagggg gctacggcga gcgattgatt tcggttagcg ataaaagcga agcggacgtg
    10021 gtcagggcct gtatgcagac cttacatagt ggacagtcgc ttgtggtggc aatagacggc
    10081 gcgctgaatt tgagtgcgcc gactatcgac tttttcggtc agcaaatcac ctactccaca
    10141 ttttgctctc gtcttgcctg gaaaatgcat ttgcctaccg ttttcagtgt tccgatatgg
    10201 aaaaacaggc atatccattt tgtgcttgag aggatggtcg atccgctgaa atttgaaagc
    10261 cagctttcat ttaccgaacg ttggaaggag aattatctgc agtgtgttac ccggatcctg
    10321 caaagcgatc cggaaaatct gcgtctttcc ggtgggattt ggcgaaacat tatacgtagg
    10381 gatagttaat aagcgattta attgcggtag atgaaaattt gtacttcaga gctgaaaatg
    10441 tggtattaac ccagatatca gtctgcaagt tgcaagtcac catcagtagc acaacgagtc
    10501 ccctcaaaca ggctgtctgc catgcctttg actctgttat atatttttca gcttctgtca
    10561 gccttgcatc tcataaaaca ttcctgacat ttatattagg gccctatccc aattcgtgtt
    10621 tttgaacatt gcccctccct gaatcatatt ccccccggca gctttaatct accaggggga
    10681 tccttattcg ctagcgtgcc attaacgcaa agacacccca gcctaagtat tcacgtgtgt
    10741 aattgacatg gcgtttgggc gcaacagtca gctcctttcg gacttcctgt acaaaatcat
    10801 catcagggtt atcctccagc cagcgacgca tggttagcca tttcgccgcc tcgtatctgt
    10861 cccagccttc ctggtctgcc agaaccattt ccaccagatc atagccccgc tcgtcaaaag
    10921 aggctacaag gccctgcagg gtgaggaagt ctgccacgga tgagacgcca caagcctgag
    10981 caatctcttc cgtcggaggt acctgacgcc agtatggttc accgataagc ataattcctc
    11041 ctggcttcag actcatggcc agaaggttca tcgtccctgc gacgccgcct gcaatccaag
    11101 ttgcgccaac gcaggccgcg atatcacatt gttcatccgc gacgtaaccc gccgcgtcat
    11161 tatgcacaaa atgaacgcgt tcactgacac cgagctcttc tgctcgtaac ttggcctgcg
    11221 cagtaaaaag tgggctcata tcgatgcctg taccggtaat accgtaatcg cgtgcccagg
    11281 tgcaaagcat ctcacccgag ccgctgccca aatcgagaac gctcatgcct ggtttcatgc
    11341 gcaacacgcg gcccagcgtg gcgtattttt ccggcgtgaa cgggttatga atgcggtgtt
    11401 cgctttcgct gatagtaaaa atacgtggaa tatccattaa tttactcctt tttttagctg
    11461 tgtattcagg gaacgccctt ccggggattt tgatttttct gccagcagag caaagagctt
    11521 gccctcaaaa gtctcgctga ccggccactc gctactgtcc gggtgtgata gtattttgaa
    11581 gcccgcgtta ccgagcaaac tggcatattc gtcatcgcgc caggccgtca tctgactgcc
    11641 aaaacggcta atgcgaccgt tttcatctat cgcccagaac tgcgttgagc tggtctgcgt
    11701 ttcttcatcc caggcgtttt ccgtcagcag cagatgagat gccgcaagga acagtccgtg
    11761 cggacaacgc tgccagctcg ccggcgccat accctgacgt ttaacttcat caaaagtatg
    11821 aacttcaaca aacagcctgc cgcctggtac cagccaccgg gcacagcggc tgataagggt
    11881 ctgagcgtca gtggcactga aaacatttag ctctccaaac gtcatcatga tgaactcgaa
    11941 ctgtgtctcc ggccagtagg tgcgaatatc ctgccggatg tagtcaatgc tcagaccggc
    12001 ggtttgcgcc tgctgacgag cccactcgat ggatgccggt gaaaaatcaa cgcccgtaca
    12061 gcaatatcca cgctccgcca gcaagtgggt gtataaaccc gggccgcagc cgatatccag
    12121 aatgcgtgca ccaaccagta gctgacgggc aatccaccca acctgctgtt caattacgat
    12181 ctgtctgcgg ctggcccagt catgatcctg cgacagatgg ttttccagca tgcgctggct
    12241 aaacgccagc tcttcccagg gtattttact ttcagctgca gacagctgca gccgaccgga
    12301 ggaagaaatg agagtactga tatccataat gctctcctta acggttatcg ggctgtgagc
    12361 gaacgttgtt cagcccggtg gtgttgatgc ggtaaggctg accgttgacg gacttgatca
    12421 gttttttggt tttgagcttt ttgaaaacgg cgagagtaca gtcggcgagc aacagccctt
    12481 cgcggctgta gcattcaaca gaggtaacgc gaccagaagc atcgcgaacg tgcacaatac
    12541 gtccaccttt tgcgagcaca tgtaaggtac gctgttcctg acgggataaa ttcatactgg
    12601 aaaacctgtt aatcaacatg agcaaaaacg agccaacatc cgcagatgtt cgcgtaaagt
    12661 ttaagcgcag cgataatcag tccgttctga gcagaacaga aaactgatta tctgatgatt
    12721 acattctcca gcatcaaagc ctcggtgaga gttgaaaggt atttacggca tgaataataa
    12781 caactgtttt ttgtaatgaa aacacaggag agaaaaaatg tgatgcggga ggaaatttca
    12841 gaaggtaatg ctggcgactt ttattgccag taagtgaact tgtcagcccg cattaggttc
    12901 tgatcggtcg cggtcggact ggaaaagaag aaggccactt tggctttctc ttttttgacc
    12961 tcatttgcgg ccatatcgac cagtatgccg cctaactgtg cagggcttgt gggagacgtc
    13021 ggtgttctgg tagctcagac cggttatccc ccgctaaaac ttatctgcgt acgcttatat
    13081 cagtactgtg ggctctgcat tgttcagtat taaagactac tttggagtaa actttaattc
    13141 ccgttgcttc agccacttat cagaaaaatc ctgtcatcga tttgaacgtg gaaactt
//
LOCUS       DAJVBX010000128        13139 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.128, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000128 DAJVBX010000000
VERSION     DAJVBX010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 13139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13139
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.128"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..551
                     /locus_tag="OPV72_003064"
     CDS             <1..551
                     /locus_tag="OPV72_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCR9915295.1"
                     /translation="FEDGKCFMFLLNGEYNSCQISASEDIIIIIDGRVLIQGVWKGFK
                     ALMQHYPHARRIWLTRRDIGKLYPHGCDRDPDIDPDLAKPVFIEHFIKYACANDVAVG
                     EIAPLTKKEEELLWHFLYKKSMSQIASSYGISRKTLYIHRLRICRKYGFKRFFHLLFI
                     YQRSRHIFASKICRVDKNADQA"
     gene            562..786
                     /locus_tag="OPV72_003065"
     CDS             562..786
                     /locus_tag="OPV72_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915296.1"
                     /translation="MKKLTMRECESINPTLLLAIKILISALDEKTKIRLREHIEKTEQ
                     EIASSIHDSIMTETFLQQMKDIRYILNIVP"
     gene            844..1203
                     /locus_tag="OPV72_003066"
     CDS             844..1203
                     /locus_tag="OPV72_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4156 domain-containing protein"
                     /protein_id="HCR9915297.1"
                     /translation="MKKILVCFVGLALTACSANSLNYGAEQVRVMTSEPGKECSYLGD
                     ITGSQGNFFTGGWTSNSNLETGARNDLKNKAYKMGDNTVVLLTQRAGQTGSSWHGSGS
                     SKQTNVTLSGNVYRCPR"
     gene            complement(1273..1830)
                     /gene="mdsC"
                     /locus_tag="OPV72_003067"
                     /pseudo
     CDS             complement(1273..1830)
                     /gene="mdsC"
                     /locus_tag="OPV72_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001521068.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter outer membrane
                     subunit MdsC"
     gene            1960..2154
                     /gene="golB"
                     /locus_tag="OPV72_003068"
     CDS             1960..2154
                     /gene="golB"
                     /locus_tag="OPV72_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gold resistance metallochaperone GolB"
                     /protein_id="HCR9915298.1"
                     /translation="MQFHIDDMTCGGCASTVKKTILTLDANATVRTDPATRLVDIETS
                     LSAEQIAAALQKAGFPPRER"
     gene            2445..3698
                     /locus_tag="OPV72_003069"
     CDS             2445..3698
                     /locus_tag="OPV72_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR9915299.1"
                     /translation="MYTPLNWTTTQRHVAFASFTSWMLDAFDFFILVFVLSDLAEWFH
                     ASVSEVSIAIMLTLAVRPIGALLFGRMAEKYGRRPILMLNILFFTVFELLSAWSPTFM
                     AFLIFRVMYGVAMGGIWGVASSLAMETIPDRSRGLMSGIFQAGYPCGYLFASVIFGLF
                     YSMVGWRGMFLIGALPVVLLPYIWFKVPESPVWLAARARKENTALLPVLRKQWKLCLY
                     LVLVMAFFNFFSHGTQDLYPTFLKMQHGFDPHLISIIAIFYNIAAMLGGIFYGTLSER
                     IGRKKAIMIAAFLALPVLPLWAFSSGSFTIGLGAFLMQFMVQGAWGVVPTWLNELVPA
                     NARAVLPGFVYQLGNLLASVNATLQARIAETHGGNYGLAMAIVAGAVAILICVFVAFG
                     RETRGVVISGTDSDALPESAIGHRT"
     gene            3887..5845
                     /locus_tag="OPV72_003070"
     CDS             3887..5845
                     /locus_tag="OPV72_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HCR9915300.1"
                     /translation="MLKDNQKHNESVAPNSAFLSELQRALPEFFIADRYNEQGELIAK
                     GGFDLAKFERALKARNIDELTSGYQIDFIGKDYAKKQAGEKSVTVIVPDVEHNTLAEN
                     KNSHNLFLTGDNLDVLRHLQNNYADTVDMIYIDPPYNTGSDGFVYPDHFEYSDRALQD
                     MFGLNDTELARLKSIQGKSTHSAWLSFMYPRLFLARKLLKDTGFIFISIDDNEYANLK
                     LMMDEIFGEGGFVTNVMWKRKKEISNDSDNVSIQGEYILVYAKTGQGALRLEPLSKEY
                     IQKSYKEPTEQFPEGKWRPVPLTVSKGLSGGGYTYKITTPNGTVHERLWAYPEASYQK
                     LVADNLVYFGKDNGGIPQRVMYAHHSKGQPTTNYWDNVASNKEGKKEILDLFGDNVFD
                     TPKPTALLKKIIKLAIDKDGVVLDFFAGSGTTAHAVMALNEEDGGQRTFILCTIDQAL
                     SNNTIAKKAGYNTIDEISRERITRVAAKIRANNPATNSDLGFKHYRFATPTQQTLDDL
                     DSFDIATGHFINTSGQLAAFTESGFTDMINPFSARGLGVPGGASGEETLLTTWLVADG
                     YKMDIDVQTVDFSGYCARYVDNTRLYLIDERWGTEQTRDLLNHIGTHQLPVQTIVIYG
                     YSFDLESIRELEIGLKQLDQKVNLVKRY"
     gene            5855..8826
                     /locus_tag="OPV72_003071"
                     /pseudo
     CDS             5855..8826
                     /locus_tag="OPV72_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459353.3"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type III restriction-modification system
                     endonuclease"
     gene            9102..9203
                     /locus_tag="OPV72_003072"
     CDS             9102..9203
                     /locus_tag="OPV72_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915301.1"
                     /translation="MLNRYYRFAVEKDDPSEAPESGDKPDSQPQKKS"
     gene            9318..10721
                     /locus_tag="OPV72_003073"
     CDS             9318..10721
                     /locus_tag="OPV72_003073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome ubiquinol oxidase subunit I"
                     /protein_id="HCR9915302.1"
                     /translation="MEFDAFFLARLQFAFTVSFHIIFPAITIGLASYLVVLEGLWLKT
                     RNPVWRSLYQFWLKIFAVNFGMGVVSGLVMAYQFGTNWSGFSQFAGSITGPLLTYEVL
                     TAFFLEAGFLGVMLFGWNKVGPGLHFLSTCMVALGTLMSTFWILASNSWMHTPQGFEI
                     HNGQVVPVDWFAVIFNPSFPYRLLHMSVAAFLSSAMFVGASAAWHLLKGNDTPAIRRM
                     FSMALWMAVVVAPVQALIGDMHGLNTLKHQPVKIAAIEGHWENTPGEPTPLTLVGWPD
                     MEAERTRYALEIPALGSLILTHSLDKQVPALKDYPKEDRPNPTVVFWSFRLMVGMGVL
                     MIFLGLASLWLRYRRRLYHSRPFMHFALWMGPSGLIAILAGWVTTEVGRQPWVVYGLL
                     RTRDAVSAHSTLQMSISLLAFFVVYSLVFGVGYIYMIRLIQKGPQPAETPTAETDGRP
                     ARPISAVGESLEQEKRE"
     gene            10718..11728
                     /gene="cydB"
                     /locus_tag="OPV72_003074"
     CDS             10718..11728
                     /gene="cydB"
                     /locus_tag="OPV72_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome d ubiquinol oxidase subunit II"
                     /protein_id="HCR9915303.1"
                     /translation="MTIDLPVIWFAIIVFATLMYIVMDGFDLGVGILFPFIRDKHDRD
                     VMVNSVAPVWDGNETWLVLGGAGLFGAFPLAYAVITDALTIPLVVMLLGLIFRGVAFE
                     FRFKATESHRAFWDKSFIVGSILATFAQGVVVSAVVSGFQVEGRTFSGSQLDWLTPFN
                     LFCGVGLVVTYALLGATWLIMKSEDPLHSRMCALSRPLLIVLLLVMGGVSVWTPLTHD
                     DIAERWFTLPNLYYFLPVPVLVLAFSVWLWRSVKKPQSHARPFILTLGLIFLGFSGLG
                     ISIWPNIIPPDISLYAAAAPSQSQSFMLVGALIIIPIILAYTFWSYYVFRGKVRHGEG
                     YH"
     gene            11728..11859
                     /locus_tag="OPV72_003075"
     CDS             11728..11859
                     /locus_tag="OPV72_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459357.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2474 domain-containing protein"
                     /protein_id="HCR9915304.1"
                     /translation="MVKVKKWSRRVVWMVAIWCASVLLLAGVGMLFRLLMTSAGFRS"
     gene            12065..13069
                     /locus_tag="OPV72_003076"
     CDS             12065..13069
                     /locus_tag="OPV72_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCR9915305.1"
                     /translation="MSPISCHSSAAPAMKKIFSVSDFIAFGERYGIDYRFPALPQYTQ
                     SSPVLHGDIEEIALPGGICITRSDVHVLQPYETTSRHSSPLYMLVVLEGNVALAVNEQ
                     TFLLSAGMAFCSQLSEQQTIRAHHGADSKLRTLSLGMYPDGGWRERLPVSLADEWERS
                     AASARVWQVPEFLLSGLRYAQQPGPHAASRQLMLEGIMLQLLGYALNLCQPATQKRGL
                     PVTGEYQRLELIRRLLEQTPEKAYTLNELARRAAMSPSSLRCKFRHAYGCTVFDYLRD
                     CRLARARRYLMEGYSVQQAAWMSGYQHATNFATAFRRRYGCSPGELRDASLTASRHCA
                     "
BASE COUNT         3051 a         3140 c         3515 g         3433 t
ORIGIN      
        1 tctttgagga tgggaagtgc tttatgttcc tacttaatgg agaatataat tcgtgtcaga
       61 tatcagctag cgaagatatc ataattatta ttgatggacg agttttgatt cagggggtct
      121 ggaaaggttt taaggcgctc atgcagcatt atccacatgc tcgtcgaatc tggctcacgc
      181 gcagagatat tggaaaactt tatccacatg gctgcgatag agatcctgat atcgatcccg
      241 atttggcaaa gcctgttttt attgagcatt tcattaaata cgcttgtgca aacgatgtag
      301 cggtcggtga aattgcgccg ttgacaaaaa aggaggaaga gttgttatgg cactttttat
      361 ataaaaagtc gatgagtcag atcgccagta gctatggcat tagtcgtaag actttgtaca
      421 ttcatagatt gcgtatctgt cgtaaatatg gcttcaagcg ctttttccat ttgctattta
      481 tttaccaaag aagtcgccat atcttcgcat ctaaaatttg ccgtgtagac aaaaacgccg
      541 atcaggcttg aagtaaacaa gatgaaaaag ttaacgatga gagagtgtga aagcatcaat
      601 cctactttgc tgcttgccat taagatactt atctcggcgc ttgacgaaaa aacaaaaata
      661 aggctcagag agcatattga aaaaactgaa caagaaatag cctcaagcat acatgatagc
      721 atcatgacag agacttttct tcagcaaatg aaagacattc gttacatctt aaatatagtt
      781 ccttgacggc gttcagaagc aagaacgcgt tattatttaa tgattaatag accaggtatt
      841 agtatgaaaa agatcttagt atgtttcgtc ggcttggctt taaccgcatg tagcgctaat
      901 tcgctgaatt atggcgctga acaggtacgg gtgatgacca gcgagccagg taaggaatgc
      961 agctacttag gagatatcac gggcagccag gggaatttct ttaccggtgg ctggacttcc
     1021 aacagtaacc tggaaacggg ggcccgtaac gatctgaaaa acaaagctta taaaatgggc
     1081 gacaatacgg tagtcctgtt aacccagcgt gcaggccaga caggaagttc atggcacggt
     1141 tcgggctcaa gcaaacaaac gaatgtcacg ttaagcggga acgtttatcg ttgccctcgt
     1201 taaccttatt ttgcaggcaa tatatgcctg tttagcgcgc gcgccgcact ggcgacgcgc
     1261 gcgctatttg ggctaacctt gctttttctc gctgtattcc cgccaaccgc cgcctaatgc
     1321 tttatacagg ctaatgatat tcaactgttg catgagacgt gtgcgtacca gacgctgttg
     1381 cgcgccataa agcatacgat gggtatcaag cagcgtaagg tagtcatcga cgccttcctg
     1441 aaaacggagt ccggccagct cataggcgat ttggctggct tcaaccgcgc gttgttctga
     1501 ttgcacctgg tcattcagcg tacgctgtcc cgccagacca tccgccacgt cgcgaaaggc
     1561 ttgctgaata acgttttcat accaggcgat ttcaatctgt ttttggacat gcgccctatc
     1621 caggtcagcg cgtaatgcgc cgccgtgaaa gagaggcaag gtgatttgcg gtagaaaacg
     1681 ccagcttccc gatcccggtt caaagagtcc gctaagagac gcgctggccg ttcccgccga
     1741 gcctgtcagg ctgatggtcg ggaagaaggc ggcgcgcgct gcgcctatcc gggcgtttgc
     1801 gccgcgcagc ctgtactcgg aggcgcgtac cggagcggta ttgcgccgtc ctcgtcgcca
     1861 cggactggca aagcgtctgt aagtcctgag attacgcttg accttccaac actgacaagg
     1921 cccagactgg caacagttcc cacacaaaag gagttcacta tgcagttcca tattgatgac
     1981 atgacctgcg gcggctgcgc cagtacggta aaaaagacga ttctgactct cgatgctaat
     2041 gcgacggtga gaaccgaccc ggcgacgcgt ctggttgaca ttgaaacgtc gctatccgcg
     2101 gagcagattg ccgccgccct gcaaaaggcc ggtttcccgc cgcgcgagag gtaatcgtca
     2161 atggcgatcg gtctggcgac aggccggtcg cgatacgcta gccacgcttc gcttttcttt
     2221 gcgtgagata atccccataa aaaatgtgac aaatcatgtg ccagtaagct ttgttaataa
     2281 tatgtaatga tttgtctatt tttgctaaca ttttacctgc tatatacaaa aagataacaa
     2341 ataagtagcg caacgctacc ttgttacgtc gctttgacga cgggagcgct ccagcgtttc
     2401 gccgcttcaa agcttgatgt tatttttgat gcaggacact acctatgtac acccccctga
     2461 actggacgac gacacaacga catgtggcgt ttgccagctt taccagttgg atgctggatg
     2521 cgtttgattt ctttatcctt gtctttgtac ttagcgatct cgccgaatgg tttcacgctt
     2581 ccgtatcgga ggtttccatt gcgattatgc tgaccctggc ggtacgtccc attggcgcgc
     2641 tgctatttgg ccgaatggcg gaaaagtacg gacgtcgacc gatactgatg ctcaatattc
     2701 tgttctttac ggtgtttgaa ctgctttccg cctggtcgcc caccttcatg gcatttctga
     2761 tttttcgggt catgtacggc gtggcgatgg gcgggatatg gggcgtcgcg tcatcactgg
     2821 cgatggaaac cattcccgat cgttcgcgtg gcctgatgtc gggcattttt caggcaggct
     2881 atccctgcgg ctatctgttc gcctcggtta tttttggcct cttctacagt atggtaggct
     2941 ggcgtggcat gttcctgatt ggcgccctgc ctgttgtctt gctgccttat atctggttta
     3001 aagtgccgga atcccccgtc tggctggcgg ccagagcgcg taaagagaat accgcgctgc
     3061 ttcctgttct gcgcaaacag tggaagttgt gtctgtatct ggtgctggtc atggcgttct
     3121 ttaacttttt cagtcacggc acgcaggatc tctatcctac cttcctgaag atgcagcatg
     3181 gttttgatcc gcatctgatc agtatcattg caatttttta taacattgcc gccatgctcg
     3241 gcggtatttt ctacggtacg ctatcggaac gtattgggcg taaaaaagcg atcatgatcg
     3301 ccgcctttct tgcgcttccg gtactcccgc tatgggcatt ttccagcgga tcattcacga
     3361 ttggtctggg cgcgttcctg atgcagttta tggtgcaggg cgcctggggt gtcgtgccga
     3421 cctggctgaa cgagctggtt ccggcgaatg cgcgcgccgt gctgccaggg tttgtttacc
     3481 aactcggtaa tttactggcg tcggttaatg cgacgttaca ggcccgcatc gcggaaacgc
     3541 atggtggcaa ttacgggttg gcaatggcga tcgtggctgg cgcggtggct attttaatct
     3601 gtgtatttgt ggcatttggt cgcgagaccc ggggagtcgt catctccggt acagatagcg
     3661 acgccctccc ggagtcggcc atcggtcatc gcacgtaaac actacgctcc tggcgcatac
     3721 tgtcgccggg agcgctcctt cctcctgtgg tttttacgcc ctttcaacga acaacaaagg
     3781 ttaatgatgg catctgcctt tcgtgaccat tacaatcatc gcttactttt ttctttataa
     3841 gaaattgatt gttggacctt aaaattgtca acggagcgaa gatatcatgt tgaaagataa
     3901 ccaaaaacac aacgagtctg ttgccccgaa tagcgccttt ctgtctgagt tacaacgtgc
     3961 attaccggaa ttttttatcg ccgatcgcta taacgagcag ggcgaactga tcgcgaaagg
     4021 cggatttgat ctcgccaaat ttgagcgcgc gctgaaagcg cgtaatattg atgagctgac
     4081 tagcggttat cagattgatt ttattggcaa agattacgca aaaaaacagg cgggtgaaaa
     4141 atccgttacc gttatcgttc ctgacgtgga acacaatact ctggcagaaa ataaaaacag
     4201 ccataatctt tttctgaccg gagataatct ggatgtttta cgccatctgc aaaataatta
     4261 cgccgatacc gtcgatatga tctatatcga tcccccttat aacaccggat cggacgggtt
     4321 tgtctatccc gatcattttg aatatagcga tcgggcgttg caggatatgt ttggtcttaa
     4381 tgataccgaa ctggcacgtt taaaatccat tcagggtaaa tcgacgcact ccgcgtggtt
     4441 atctttcatg tatccgcgtc ttttcctggc caggaagctc ctgaaagata ccgggtttat
     4501 ttttatctct atcgacgata atgagtacgc caatcttaaa ttaatgatgg atgagatttt
     4561 tggcgaaggc ggatttgtca ccaatgtgat gtggaagcgc aaaaaagaga tttctaacga
     4621 ctctgataac gtttccatcc agggggaata cattcttgtt tacgccaaaa ccggtcaggg
     4681 cgctttacgt ttagaaccgc tttctaaaga gtatattcag aaatcctata aagaaccgac
     4741 cgaacagttt ccagaaggga aatggcgacc ggtgccgtta acggtgtcaa aagggctgag
     4801 cggcggcggc tatacctata aaattaccac gccgaacggt acggtacacg aaagactatg
     4861 ggcttatcct gaagccagtt accaaaaact ggtggccgat aatctggtct attttggcaa
     4921 agataacggc ggtattcccc agcgagtcat gtacgcgcat cacagtaaag ggcagccaac
     4981 gaccaattac tgggataacg tagcgtcgaa taaagagggg aaaaaggaga ttctggatct
     5041 cttcggcgac aacgtttttg atacgccgaa accgaccgca ttattgaaga aaatcatcaa
     5101 gctcgctatc gataaagacg gcgtcgttct ggactttttt gccggttccg gcaccacggc
     5161 ccatgcggtg atggcgctga atgaagaaga tggggggcag cgcacgttta ttctgtgtac
     5221 tatcgatcag gcattaagca ataacactat cgcgaaaaaa gcaggttata acactattga
     5281 tgaaatcagc cgcgagcgaa ttacacgcgt tgcggcgaag atccgcgcca acaatcccgc
     5341 gaccaatagc gatctcggtt ttaaacatta tcgttttgcc actccgacac agcagacgct
     5401 ggacgatctg gatagcttcg atattgctac cggccatttt atcaatacca gcggtcaact
     5461 ggccgctttc accgagtcag gatttaccga catgatcaat cctttttccg ccagaggatt
     5521 gggcgtgccg ggcggcgcaa gcggcgaaga gaccttatta acgacatggc tggtcgccga
     5581 tggttataaa atggatattg acgtacagac cgttgatttt tccggctatt gcgccaggta
     5641 tgttgataat acgcgcctgt atctgattga tgaacgatgg ggaacagagc agacccgcga
     5701 tcttctcaac cacattggta cgcaccagct tccggttcag accattgtca tttacggcta
     5761 ctctttcgac cttgaatcca ttcgtgaact ggaaatcggc ttaaaacagc ttgatcaaaa
     5821 agtgaacctg gtgaagcgtt attaagaggg gatgatgatg aatattttgc tggaagaact
     5881 tccccatcag gaacaggcgt tagcggcgat tctggcgagt ttcaccggta tcgatcacgc
     5941 gcaggccgat cataatcact atgctaatcc gctgattaag ggacgttacg acgataaggc
     6001 caatattgac gttaaaatgg agaccgggac gggcaaaacc tatgtctata ctcggttgat
     6061 gtatgaactg catcagaagt atggcctctt caaatttgtg ctggtggtgc cgacgccagc
     6121 cattaaagaa ggcgcgcgga actttatcac cagcgattac gccagacagc atttttcaca
     6181 gttctacgaa aatacgcgga tggaattttg caccatcaac gccggtgatt ttaaagtaaa
     6241 gtcggggcgt aaaaattttc cggcccagtt attaagtttt actgatgcca gccgtcgtga
     6301 tagccatacg attcaggttt tgctgatcaa tgcgcaaatg ctcaattccg ccagtatgac
     6361 gcgagacgat tacgatcaac gctactgggc gggctgacgt cgcctgttaa agggctgcaa
     6421 atgacgcgac cggtggtcat tattgatgaa ccgcatcgtt ttgtgcgaga taacaaattt
     6481 tatcgagcga ttcaggccat tcagccgcaa atgatcgtcc gctttggcgc taccttcccg
     6541 gatattgtcg aaggtaaggg taaaaataaa tgtgtacgta aagattacta tcgccggcaa
     6601 ccgcagtttg atctcaacgc ggtggacagt tttaacgatg gtttggtgaa aggtattgat
     6661 atttattacc cgaatctccc cgaagaacag gccaacaatc gttatatcgt tgacagcgtc
     6721 acggcaaaga aattaatcct ccgacggggg agcaaaattg ccgaggttgg cgtgggcgaa
     6781 aatctcgccg atgtcgatgc aggatttgaa ggcagtatcg aatatgccgg cagtaaaatg
     6841 ttgtcgaacg atctggagct ggaggcaggg atggcgctgg tgccaggaac ctttggcgcg
     6901 agctaccagg aactgattat tcaggacgct atcgataagc attttgacac tgagcaggca
     6961 aatttcttac gcagcaatga gccagaaaat aatgccccgc gtattaagac cttaagcttt
     7021 ttctttattg acagtattaa aagctatcgt gatgacgaag gttggttgaa actgaagttt
     7081 gagtgtttac tgaaaaagaa actgacgcaa ctgattgacg attatcagcg caagaccctg
     7141 ccgcgagaag tggagtatct gtcgtttctg caggccacgc tcgccagcct gcactcggat
     7201 aaccaaaacg tccacgctgg ttactttggc gaagaccgcg gaagcggcga tgaggcgatc
     7261 caggctgagg tagatgatat tctgaaaaat aaagagaagt tgctcagttt ttcagaccat
     7321 cacggcaact gggaaacgcg ccgctttctg ttttcaaaat ggacgcttcg cgaaggctgg
     7381 gataacccga atgtttttgt cattgctaaa ttacgttctt ccggtagcga gtcgagcaaa
     7441 attcaggaag tggggcgcgg cctgcggcta ccggtagatg aaaacggcca tcgcgttcat
     7501 caggaagagt ggccgtcccg actgtcgttt ctgattggtt atgatgaaaa agcgtttgcc
     7561 agtatgctgg ttgatgagat taatcgcgac agcaaagttc agcttaacga gcagaagctg
     7621 gatgaggcga tgatcacact catcgtcacc gagcgacaaa aagtcgatcc tgcgtttacg
     7681 gagcttcgtt tgctggaaga tctggatgat aaaaaactga tcaaccggag taatgagttt
     7741 aaacccagcg tcacgcttaa cggggaaacc aaaagtggct ttgcgtggct actggagttc
     7801 taccctgagc tgacgcaggc gcgggtgcga gcggatcgca ttcgtgacaa taagcccgcc
     7861 tcccgactgc gagtcaggtt acgcaaagag aattgggaac aacttagcag tatctgggag
     7921 cagttttccc gccgttatat gctgcaattc gagcgtagcg gcgcttctct ggaacagatt
     7981 gccgccgagg tgctgcgcga tccgtcgctg tatatacgcc agaagccaag ccaggtgcaa
     8041 caacggctgg tatcgaatga agataatggc cgttttgaag tggcgcagcg ggaaggcgaa
     8101 ttagccgcca gcgaatttat ggcgggcatg aaatatggcc attttcttaa gcaactggcg
     8161 ttacgcacca gtctgccgat taacgtcctg cacccggtgt taatggcgat gctgcgtgat
     8221 gttttgcacg gagattcacg ctatttaagc gagatctcgt tggacaatat gacccgcgca
     8281 ttacagacgc ggattaatgc gcattttgcg cagcgccacg attatctgcc tctcgatttt
     8341 caggcttcaa cgtcggtatt tgattctacg gcacggcagt tcagagagga gattagcgct
     8401 gaaattgtgg ggaaaaatgt ggatgagaat gcgatagacg atccccgttc tctctatcaa
     8461 ataccgccgt tgcgttatga cagcgtcgat ccagaattgc cgctattaaa atacgattat
     8521 ccgcaacagg tttctgtgtt tggcaaactg cctaagcggg ccattcagat ccccaaatat
     8581 acggggggct ctactacgcc ggattttgtg taccgtattg agcgtcagga cgccgacagt
     8641 gtttatttac tggttgaaac taaagcagaa aatatgcgcg taggcgatca ggttattctt
     8701 gatgcgcaac gtaaattctt cgatatgctg cgtcggcaaa atatcaatgt cgagtttgcg
     8761 gaagcgacca gcgcgccggc ggtattttct accatcaatg gcttgattgg ggggaaggca
     8821 aactaacggg tttgaataga ccttaacggt tatctttttg ataggccata taaaatggcc
     8881 gccgcgcagc gagcgttgcg gtcattctcc tgtgctaatc ccccgtcccg taaaccgcgt
     8941 tgacttgaag gttatcgttt tacgtctatt cttaactttc agctaagtgt attttgctga
     9001 aattgcaaat agtcttgaag acgctgtttt tttgttttgc cgttattttt ataacggcca
     9061 ggtagatatt gccaagtgaa tgtaactaag ggagacatgt tatgctaaat agatactacc
     9121 gtttcgctgt cgaaaaagac gacccctccg aagcgccaga gtcgggcgat aagcctgaca
     9181 gccagccgca aaaaaaatcg taatttatct ggatattccc cgacgttttt acgtttgggg
     9241 aaaataaccg tttcgtttca acctggttgc gaacagtgaa tattttacac gaagtgacta
     9301 tataaacggg agggaacatg gagtttgatg cattcttttt agcgagactc cagtttgcct
     9361 ttaccgtctc ttttcatatt attttccccg cgattacgat tggcttagcc agttacctgg
     9421 tggtactgga aggtttatgg ctaaaaacgc gtaatcctgt ctggcgctcg ctctatcagt
     9481 tctggctcaa aatttttgcc gtcaacttcg ggatgggcgt ggtctccggt ctggtcatgg
     9541 cttaccagtt cggaacgaac tggagcggtt tttcccagtt cgccggcagt atcaccgggc
     9601 ctttattaac ctatgaagtg ctcaccgcat tcttcctgga agcgggattc ttaggcgtga
     9661 tgctttttgg ctggaacaaa gtcgggccgg gcctgcattt cttgtctacc tgtatggtgg
     9721 cgttgggcac gttaatgtcg acgttctgga ttctggcgtc taatagctgg atgcataccc
     9781 cgcagggatt tgaaattcat aacggtcagg tagtcccggt ggactggttc gcggtgattt
     9841 tcaacccgtc gttcccgtat cgcctgttgc atatgtccgt tgcggcgttt ttaagtagcg
     9901 cgatgtttgt cggcgcgtcc gcagcctggc atttactgaa aggtaacgat acgccggcta
     9961 tccgccgtat gttctcgatg gcgctatgga tggcggtcgt ggtggcaccc gttcaggcat
    10021 tgattggcga tatgcatggc cttaacaccc tgaagcatca gccggtcaaa atcgccgcga
    10081 ttgaggggca ctgggaaaat acgcccggcg agccaacgcc gcttacgctg gtaggctggc
    10141 cggatatgga ggcggaacgg acccgctatg cgcttgagat cccggcgttg ggcagtctga
    10201 tcctgacgca tagcctggac aaacaggtgc ctgcgctaaa agattatccc aaagaggatc
    10261 gccccaaccc taccgtggtg ttctggtctt tccgtctgat ggtgggcatg ggcgtactga
    10321 tgatctttct ggggctggcc agcctgtggc tacgctaccg acgccgcctg tatcattcgc
    10381 ggccctttat gcactttgcg ctgtggatgg ggccgtccgg gcttatcgcc atccttgccg
    10441 gatgggtgac gactgaagta ggacgtcagc cgtgggtggt ctatggcctg ctgcgaacgc
    10501 gtgatgcggt ttccgcgcac agcaccttgc aaatgagcat cagtttgctg gccttctttg
    10561 tggtctattc cctggtgttt ggggttggct atatttatat gattcgtctt atccagaaag
    10621 ggccgcagcc ggcggagaca ccgaccgctg aaaccgatgg cagacccgcg cgtcctatct
    10681 ctgccgtggg agaatcgctt gagcaggaga aacgcgaatg accatcgatc ttccggttat
    10741 ctggtttgct attatcgtgt tcgccacgct gatgtatatc gtgatggatg gtttcgatct
    10801 gggcgtcggt atcctgtttc cgtttattcg tgataaacac gatcgcgatg ttatggtgaa
    10861 ctcggtcgcg ccggtatggg acgggaacga aacctggcta gtgctgggcg gggccgggct
    10921 ttttggcgcg ttcccgttgg cttatgccgt catcaccgac gcgctgacta tcccgctggt
    10981 ggttatgctg cttggtctta tctttcgcgg cgtcgctttt gaattccgtt ttaaagccac
    11041 cgagtcgcat cgcgcgttct gggataaatc ctttatcgtc gggtcaatcc tggcgacctt
    11101 tgcccagggg gttgtggtga gcgcggtggt gagcggtttt caggtggaag ggcgaacctt
    11161 tagcggttcg cagcttgact ggctgacgcc gtttaatctg ttctgcggcg tcggtctggt
    11221 cgtcacctac gcgctgctgg gcgctacctg gctgattatg aaaagcgaag atccgctgca
    11281 tagccggatg tgcgcgctgt cgcgcccgtt gttgatcgtc ttgttgctgg tgatgggggg
    11341 cgtcagcgtg tggacgccgc tcacccatga cgacatcgcc gagcgctggt tcacgctgcc
    11401 caatttatac tacttcctgc cggtgcctgt gctggtgttg gcttttagcg tctggctatg
    11461 gcgcagcgtg aaaaaaccac aatcccatgc gcgtccattt attctcacgc tagggctgat
    11521 ttttctgggg ttcagcgggt taggaatcag tatttggccg aatattattc caccggatat
    11581 ttcgctgtat gccgccgccg cgccgtcgca aagtcaaagc tttatgctgg ttggggcgct
    11641 gataatcatc ccgattattc tggcttatac cttctggagc tactacgtct tccgtggaaa
    11701 agtgcgacat ggagagggat atcactgatg gttaaagtga aaaaatggtc gcggcgagtc
    11761 gtatggatgg tcgcgatatg gtgcgccagc gtgcttctgc tggcgggcgt cggaatgttg
    11821 ttcagactgc tcatgacctc cgcaggattt cgctcctgac tgataccccc ggacgcgctt
    11881 tcgtctctcg cgaaagcgcg tttttatcga cagatcggcg tttatcgatc acctttgctc
    11941 gccttatctc tcccctcaat agcggttgat aattattctc atctttattg tcgttcccgg
    12001 gccgcagtga tatggttaca cagtggctaa cgctctggta taacgcagat aaacggtatt
    12061 gataatgtct ccgatctcct gtcactcttc cgccgccccg gcgatgaaaa agatcttttc
    12121 cgtcagcgac ttcatcgcgt ttggcgagcg ttatggcatt gattaccgct tccctgcgtt
    12181 accgcagtat acgcagagta gtcccgtact tcatggcgat atcgaagaga tagcgcttcc
    12241 cggcgggatt tgcattacac gctcggatgt tcacgtgtta caaccttatg aaaccacctc
    12301 tcgccatagc agtccgctgt atatgctggt ggtgttggaa ggtaacgtcg cgctggctgt
    12361 caatgagcag acctttttgt tgagcgcggg gatggcgttt tgctcgcaac tgagtgagca
    12421 gcagacgata cgcgcccatc acggcgcaga cagtaaattg cgcaccttat cgctgggaat
    12481 gtacccggac ggcgggtggc gggagcgttt gcctgtctcg ctggcagacg agtgggaacg
    12541 tagcgcggcc tcggcgaggg tctggcaggt gccggagttt ctgctttcgg ggctacgtta
    12601 tgcgcagcag cccggacctc atgcggcgtc acgccagtta atgctggaag gcatcatgct
    12661 gcaattgctg ggctatgcgt taaatctatg tcagcccgca acgcaaaaac gcggacttcc
    12721 cgtcaccggt gaataccagc ggctggagct cattcggcgt ttactggagc aaacgccgga
    12781 aaaagcctac acgctgaacg aactggcgcg tcgggcggca atgagtccga gtagcctgcg
    12841 gtgcaagttt cgccatgcct atgggtgtac cgtgtttgat tatctgcgcg attgccgcct
    12901 ggcgcgcgcg cgtcgttatc tgatggaggg atacagcgtg cagcaggccg cctggatgtc
    12961 aggctatcaa catgccacta actttgcgac ggcatttcgt cggcgttatg gctgctcgcc
    13021 cggcgagctg cgtgacgcgt ctctgacggc gtcccgccac tgtgcgtaac gcgccccgcc
    13081 agagcggtaa tatccgccgc taacccggtt ttctgccgct ttgggtgatt ttttatcat
//
LOCUS       DAJVBX010000129        13137 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.129, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000129 DAJVBX010000000
VERSION     DAJVBX010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 13137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13137
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.129"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            1..1302
                     /locus_tag="OPV72_003077"
                     /pseudo
     CDS             1..1302
                     /locus_tag="OPV72_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460799.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(1350..2231)
                     /gene="htpX"
                     /locus_tag="OPV72_003078"
     CDS             complement(1350..2231)
                     /gene="htpX"
                     /locus_tag="OPV72_003078"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014229823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease HtpX"
                     /protein_id="HCR9915306.1"
                     /translation="MMRIALFLLTNLAVMVVFGLVLSLTGIQSSSVQGLLIMALLFGF
                     GGSFISLLMSKWMALKSVGGEVIEQPRNERERWLMNTVATQARQAGIAMPQVAIYHAP
                     DINAFATGARRDASLVAVSTGLLQNMSPDEAEAVIAHEISHIANGDMVTMTLIQGVVN
                     TFVIFISRIIAQIAAGFLGGNRDEGEGSNGNPLIYFAVATVLELVFGILASIITMWFS
                     RYREFHADAGSAKLVGREKMIAALQRLKTSYEPQEATSMMAFCINGKSKSLSELFMTH
                     PPLDKRIEALRSGEYLK"
     gene            complement(2424..4472)
                     /gene="prc"
                     /locus_tag="OPV72_003079"
     CDS             complement(2424..4472)
                     /gene="prc"
                     /locus_tag="OPV72_003079"
                     /EC_number="3.4.21.102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxy terminal-processing peptidase"
                     /protein_id="HCR9915307.1"
                     /translation="MNTFFRLTALAGLLALAGQSFAVEDITRADQIPVLKEETQHATV
                     SERVTSRFTRSHYRQFDLDEAFSAKIFDRYLNLLDYSHNVLLASDVEQFAKKKTVLGD
                     ELRTGKLDVFYDLYNLAQKRRFERYQYALKVLERPMDFTGNDTFNLDRSKAPWPKDEA
                     ELNALWDGKVKFDELSLKLTGKSDKEIRETLTRRYKFAIRRLAQTNSEDVFSLAMTAF
                     AREIDPHTNYLSPRNTEQFNTEMSLSLEGIGAVLQMDDDYTVINSLVAGGPAAKSKSI
                     SVGDRIVGVGQAGKPMVDVIGWRLDDVVALIKGPKGSKVRLEILPAGKGTKTRIITLT
                     RERIRLEDRAVKMSVKTIGKEKVGVLDIPGFYVGLTDDVKVQLQKLEKQNVNSIVINL
                     RSNGGGALTEAVSLSGLFIPSGPIVQVRDNNGKVREDSDTDGVVYYKGPLVVLVDRFS
                     ASASEIFAAAMQDYGRALIVGEPTFGKGTVQQYRSLNRIYDQMLRPEWPALGSVQYTI
                     QKFYRVNGGSTQRKGVTPDIIMPTGNEETETGEKFEDNALPWDSIDAAKYVKSDDLAP
                     FGPELLKEHNARIAKDPEFQYIMKDIARFNAMKDKRNIVSLNYAQREKENNEEDALRL
                     ARINDRFKREGKPLLKKLDDLPKDYQEPDPYLDETVKIALDLAHLEKEKPAEQAATDK
                     "
     gene            complement(4492..5178)
                     /gene="proQ"
                     /locus_tag="OPV72_003080"
     CDS             complement(4492..5178)
                     /gene="proQ"
                     /locus_tag="OPV72_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone ProQ"
                     /protein_id="HCR9915308.1"
                     /translation="MENQPKLNSSKEVIAFLAERFPHCFSAEGEARPLKIGIFQDLVE
                     RVGGEMNLSKTQLRSALRLYTSSWRYLYGVKPGATRVDLDGNPCGELEEQHVEHARKQ
                     LEEAKARVQAQRAEQQAKKREAAAAAGEKEDAPRRERKPRPVARRKEGAERKPRADKP
                     TTKAPRAPREEKHTPVSDISVLTVGQSLKVKAGNNAMDATVLEITKDGVRVQLNSGMS
                     LIVRAEHLVF"
     gene            complement(5276..5773)
                     /locus_tag="OPV72_003081"
     CDS             complement(5276..5773)
                     /locus_tag="OPV72_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HCR9915309.1"
                     /translation="MSKTELYAALNRDFQSLMAGETSFLATLANTSALLFERLTEVNW
                     AGFYLLEGDTLVLGPFQGRIACVRIPVGRGVCGAAVAQNKVQRIDDVHAFDGHIACDA
                     ASNAEIVLPVTVGERIIGVLDIDSTAFGRFTEEDEHGLRTLVAQLETVLATTDYKKFF
                     ASVAG"
     gene            5902..7185
                     /gene="yebS"
                     /locus_tag="OPV72_003082"
     CDS             5902..7185
                     /gene="yebS"
                     /locus_tag="OPV72_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane integrity lipid transport subunit YebS"
                     /protein_id="HCR9915310.1"
                     /translation="MALNTSHVTPTKKLTIRSVSEALPRSHYQRCPECDMLFSLPEMS
                     AHQSAYCPRCQAKIRDGRDWSLTRLTAMAVTMLLLMPFAWSEPLLHIYLLGVRIDANV
                     MHGIWQMTQQGDPLTAAMVLFCVVGAPLILVFSIAYLWFGSLLGMNLRPVLLMLEKLK
                     EWVMLDIYLVGIGVASIKVQDYAFLQPGIGLLAFVSLVVLSILTMIHLNVEQLWERFY
                     PQHPAQRADERLRVCLGCHFSGYPDAKGRCPRCHIPLRLRRKQSIQKCWAALLASIVF
                     LLPANLLPISVIYINGGRQEDTILSGIMSLASSNIAVAAVVFIASILVPFTKVIVMFT
                     LLLSIHFKCQQGLRTRILLLRLVTWIGRWSMLDLFVISLTMSLINRDQILAFTMGPAA
                     FYFGAAVILTILAVEWLDSRLLWDAHESGNARFED"
     gene            7154..9787
                     /locus_tag="OPV72_003083"
     CDS             7154..9787
                     /locus_tag="OPV72_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416348.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MCE family protein"
                     /protein_id="HCR9915311.1"
                     /translation="MSQETPASKTEAQIKTKRRISPFWLLPLIALMIAGWLVWDSYQD
                     RGNSVTIDFMSADGIVPGRTPVRYQGVEVGTVEDVSLSKDLRKIEVRVSIKSDMEDAL
                     REETQFWLVTPKASLAGVSGLDALVGGNYIGMMPGKGKPRDHFVALDTQPKYRLSNGD
                     LMIHLNAPDLGSLNSGSLVYFRKIPVGRVYDYSINPNKQGVTIDVLIERRFTDLVKKG
                     SRFWNVSGIDADLSLSGAKVKLESLAALVNGAIAFDSPDNSKPAAQDDTFGLYKDLAH
                     SQRGVIVKLELPSGDGLKAESTPLMYQGLEVGELSKLTLNPGGKVTGEMTVDPSVVPL
                     MRENTRIELRNPKLSLSDANISSLLTGKTFELVPGDGEPRSEFVVVPGEKALLHEANA
                     LTLTLTAPESYGIEPGQPLILHGVKIGQVIERNLSSKGVSFIVAIEPQHRDLVQGDSK
                     FVVNSRVDVKVGLDGVEFLGASASEWIDGGIRILPGTSGKMKSTYPLYANLEKALENS
                     LSDLPTTTLTLTAETLPDVQAGSVVLYRKFEVGEVITVRPRANTFDIDLHIKPEYRHL
                     LTSNSVFWAEGGAKVQLNGSGLTVQASPLSRALKGAISFDNLSGASASRRKGDKRILY
                     ASETSARAVGGQITLHAFDAGKLAEGMPIRYLGIDIGQIQTLELITARNEVQAKAVLY
                     PEYVQTFARAGTRFSVITPQISAAGVEHLDTILQPYINVEPGRGAARRDFELQEATIT
                     DSRYLDGLSIVVEAPEAGSLNIGTPVLFRGIEVGTVTGMSLGSLSDRVMITLRISKRY
                     QYLVRNNSVFWLASGYSLDFGLTGGVVKTGTFNQFIRGGIAFATPPGTPLAPKAQAGK
                     HFLLQESEPKEWREWGTALPR"
     gene            9865..11304
                     /gene="rsmF"
                     /locus_tag="OPV72_003084"
     CDS             9865..11304
                     /gene="rsmF"
                     /locus_tag="OPV72_003084"
                     /EC_number="2.1.1.178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1407)-C(5))-methyltransferase
                     RsmF"
                     /protein_id="HCR9915312.1"
                     /translation="MAQHAVYFPDAFLTQMREAMPSTLSFDEFISACQRPLRRSIRIN
                     TLKISVADFLALIAPYGWSLTPIPWCHEGFWIERDDEEALPLGSTAEHLSGLFYIQEA
                     SSMLPVAALFADDNHPQRVMDMAAAPGSKTTQIAARMGNRGAILANEFSASRVKVLHA
                     NISRCGIANTALTHFDGRVFGAALPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESN
                     LDIAATQRELLDSAFHALRPGGTLVYSTCTLNRQENEAVCLWLKETYADAVEFLPLGD
                     LFPDADRALTPEGFLHVFPQIYDCEGFFVARLRKMSSLPAMPAPGYKVGAFPFTSLKG
                     REALNVTQAANAVGLLWDENLHLWQREKEVWLFPAEIESLIGKVRFSRLGIKLAESHN
                     KGYRWQHEATIALACPTHAHAFELSVQEAEEWYRGRDIYPQTPPAADDVLVTFQHQPL
                     GLAKRIGARIKNSYPRELVRDGKLFTGNS"
     gene            11422..11658
                     /locus_tag="OPV72_003085"
     CDS             11422..11658
                     /locus_tag="OPV72_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707284.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1480 family protein"
                     /protein_id="HCR9915313.1"
                     /translation="MKTSVRIGAFEIDDAELHGESPGERTLTIPCKSDPDLCMQLDAW
                     DAETSVPAILNGEHSVLFRNHYDPKSDAWVMRLA"
     gene            11769..11960
                     /locus_tag="OPV72_003086"
     CDS             11769..11960
                     /locus_tag="OPV72_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebW family protein"
                     /protein_id="HCR9915314.1"
                     /translation="MFALVLFVCYLDGGCEDIVVDIYDTEQQCLYSMDDQRIRHGGCF
                     PVEDFIDGFWRPAQQYSDF"
     gene            complement(11979..12629)
                     /gene="pphA"
                     /locus_tag="OPV72_003087"
     CDS             complement(11979..12629)
                     /gene="pphA"
                     /locus_tag="OPV72_003087"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-serine/threonine phosphatase"
                     /protein_id="HCR9915315.1"
                     /translation="MMRPEEIYQRIEAKNWRHVWVVGDIHGCFSMLMKRLRECQFDPQ
                     QDLLVSVGDLIDRGPDSLGCLALLRESWMTAVRGNHEQMALDARASSQSTLWLMNGGD
                     WFTRLTAEHAAQAEALFILCQRLPWILEVRCRHSTHVIAHADYPASTYQWQKKVDLHQ
                     VLWSRERLINKRGGISGADHFWFGHTPLRRRMDFANIHYIDTGAVFGGQLTLARIQ"
     gene            complement(12853..13017)
                     /locus_tag="OPV72_003088"
     CDS             complement(12853..13017)
                     /locus_tag="OPV72_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915316.1"
                     /translation="MPPLKKIVLRLFVGAMVATVTTPALALVCLEDHSAKECAISCAE
                     VMWFMFPICF"
BASE COUNT         2964 a         3585 c         3315 g         3273 t
ORIGIN      
        1 atttcgatgg cggttctgga tggcgcaatc gctaatgtcg cgctgccaac cattgcgact
       61 gatttacatg cctcccctgc cagctctatc tggattgtca atgcgtacca aatcgccatt
      121 gtcgtctcac tactttccct gtctttttta ggcgacatgt ttggttatca ccggatctat
      181 aaatgtggtt tagtggtatt tctgctttca tcattgtttt gcgcgctttc agactcgctg
      241 cagatgctga cgctggcgcg catcgcgcag gaatttggcg gcgcggcgct aatgagcgta
      301 aacacggcgc tgattcgtct tatctacccc cagcgtcatc tgggacgagg tatgggaatt
      361 aactctttta tcgtcgccgt ctcttccgcc gcgggtccga cgatcgccgc ggcgattttg
      421 tccatctcat catagaaatg gctgtttctg attaatgtcc cgttaggtat catcgcgtta
      481 attctggcca tacgcttttt accagcaaac atcgcccatg acactaagcc gcgctttgac
      541 ttaccgagcg cggtaatgaa tgcgctcaca tttggtctgc tgattaccgc attgagcggc
      601 tttgcccagg gacagtcgct aacgttgatt ggcgcagagc tgctcgttct ggtcgtggtc
      661 gggtttttct tcgtgcgccg ccagctttct ttgcccgtcc ctttgttacc catcgacttg
      721 ttacgcattc cgcttttttc actctcgatc ggcacgtcaa tttgctcgtt ctgcgcgcaa
      781 atgttagcca tggtctcgct acctttttat ctgcaaaccg tgctgggccg tagcgaagta
      841 gaaaccggcc tgttattgac gccctggccg ctggcaacga tggtgatggc gccgctggcg
      901 ggatacctga tagaacgtct tcatgccggt ttgctggggg cgctgggaat ggtgataatg
      961 gcagccgggt tgtttgcgct ggtcatgttg ccaggcaccc cctccgatct gaatattatc
     1021 tggccgatga tcctttgcgg cgcagggttt ggcctgttcc agtcgccgaa taatcacacc
     1081 attatcactt ccgcgccgcg tgagcgcagc ggtggcgcca gcgggatgct gggcacggcg
     1141 cgactgttag gccaaagtac tggcgccgcg ctggtagcgc tgatgttgaa ccagtttggc
     1201 gatagcggta cgcatctttc gctgctcgcg gcggcgatcc tggcgactct cgcggcggtg
     1261 gtgagcggtt tacgtattac gcaaccacgc gttcaggcgt aaaaaaagcg cgtcattcga
     1321 cgcgcttttc atacttgcca gtgggcttat tatttcaggt actcgccgct acgcagcgct
     1381 tcaatgcgtt tatccagcgg tgggtgcgtc ataaacagct cgcttaacga tttcgattta
     1441 ccgttaatac aaaacgccat catgctggtc gcttcttgcg gctcgtagct ggttttcagg
     1501 cgctgcaacg cggcaatcat tttttcacgg cccaccagct tcgccgatcc cgcatcggca
     1561 tgaaactcac ggtaacggga gaaccacatg gtgataatgc ttgccagaat accgaagacc
     1621 agttccagca ccgtcgcaac ggcgaaatag attagcggat taccgttact tccttcgcct
     1681 tcatcacggt tgccgcccag aaaaccagca gcaatttgcg cgataatgcg cgaaataaag
     1741 ataacgaagg tgttaaccac cccctgaatc aacgtcatcg tcaccatatc gccattggca
     1801 atatggctga tttcatgcgc aatgacggct tccgcctcgt cagggctcat attttgcaac
     1861 agaccggtgc tcacagcgac caatgaggcg tcacggcgtg cgcccgtcgc aaacgcgtta
     1921 atgtccggcg catggtagat agcaacctgc ggcatggcga taccagcctg gcgcgcttgc
     1981 gttgctacgg tgttcatcaa ccagcgttct ctttcattgc gaggctgttc aataacttcc
     2041 cctcctacgg attttaacgc catccatttg gacatcagca atgaaataaa agaaccgcca
     2101 aaaccaaaca gcagcgccat gatcagcaag ccttgcacgc tgctcgactg tatccctgtc
     2161 aggctcagaa ccagcccgaa aacgaccatc acggccaggt tcgtcagcag gaagagcgcg
     2221 attcgcatca taattttctt ttaacctcaa tttaacaaag cgcactatgc gattacccac
     2281 atcgtatggg tcttatggct attttcaagt atcaccaggc ggtaagtcac gagaaaaaca
     2341 caactttaca ttttgtagca ttatcctgac gacttctgcg cttgttaaaa aaaacaggca
     2401 caattttttg tgcctgttta gcgttactta tcggttgccg cttgctccgc tggtttttct
     2461 ttttcaagat gcgccaggtc cagagcaatc ttcaccgttt catcaaggta cgggtccggc
     2521 tcctggtaat cctttggcag atcgtccagt ttcttcaaca acggtttacc ctcacgttta
     2581 aaccgatcgt taatacgcgc cagacgcaga gcgtcttctt cattgttctc tttctcacgc
     2641 tgcgcataat tcagagagac gatgttgcgc ttatccttca tggcattgaa acgtgcgata
     2701 tccttcatga tgtactgaaa ctcaggatct ttggcgatac gcgcgttgtg ctctttcaat
     2761 aattccgggc caaacggggc caaatcgtcc gatttcacgt atttcgccgc atcaatgcta
     2821 tcccacggca aggcgttatc ttcaaatttt tctccggttt ccgtctcttc attgccagtc
     2881 ggcatgatga tatccggcgt gaccccttta cgctgcgtac taccgccgtt gacacggtaa
     2941 aacttctgaa tggtgtactg caccgaaccc agcgcaggcc attccgggcg gagcatctga
     3001 tcgtaaattc ggtttagcga acgatattgc tgtaccgtcc ctttaccgaa ggtcggctca
     3061 ccgacaatca gcgcgcgacc ataatcctgc atcgcggcag cgaagatttc cgatgccgaa
     3121 gcactgaaac gatcgaccag caccaccagc gggcctttgt agtagaccac gccgtcggtg
     3181 tcgctatcct cacgcacttt accgttattg tcgcgcacct gaactatcgg accagaaggg
     3241 ataaacaggc cggaaagcga aacggcttcc gtcagcgccc caccgccgtt tgaacgcaga
     3301 ttgataacga tgctgttaac attctgtttt tccagcttct gaagctgaac tttgacatca
     3361 tcggtcaagc caacatagaa gcctggaata tccagtacgc caactttttc cttgccgatg
     3421 gttttcaccg acattttaac cgcgcgatct tcaagacgaa tccgttcacg cgtcagcgtg
     3481 ataatacgcg ttttcgtccc tttgccagcc ggcagtattt ccagtcggac cttgctgcct
     3541 ttcggccctt tgatcagcgc caccacatcg tcaagacgcc agccaatgac gtcgaccatc
     3601 ggttttccgg cctgccctac gccgacgata cgatcgccga cgctaatcga cttgctcttc
     3661 gctgccgggc caccggcgac caatgagtta atgacagtgt aatcgtcatc catttgcagc
     3721 accgcgccga taccttccag agacaggctc atttcggtat taaactgctc ggtattgcgg
     3781 ggagaaagat aattcgtatg cgggtcgatt tcacgcgcaa aagcggtcat cgccagcgag
     3841 aacacatctt cactgttggt ctgcgccagg cggcgaatag cgaatttgta gcgacgcgtc
     3901 agcgtttcgc gaatttcttt gtcgctcttg ccggtgagtt tcagactgag ctcatcgaat
     3961 ttcactttac catcccacag cgcatttagc tcagcctcat ctttcggcca gggcgcttta
     4021 ctgcggtcca ggttaaacgt atcgtttccg gtgaaatcca ttggccgttc cagcactttt
     4081 agcgcgtact ggtaacgttc aaaccggcgc ttttgcgcca ggttataaag atcgtaaaaa
     4141 acatccagct tacccgtgcg cagctcatcg cccaacacgg ttttcttttt cgcaaactgc
     4201 tcgacatcgc tcgccaacaa aacgttgtgg ctatagtcga gaagattcag atagcgatca
     4261 aaaatctttg ccgaaaatgc ctcatccaga tcgaactggc gatagtggga gcgggtaaaa
     4321 cgcgacgtta cgcgctcgct caccgtcgca tgttgcgtct cttcctttag tacgggaatt
     4381 tgatcggcac gcgtaatatc ttccacggcg aaggactggc ctgctaatgc aagcaggcca
     4441 gctaacgcgg taagcctaaa aaaagtgttc atgccaggcc tggcctccgt ttcagaacac
     4501 caggtgttct gcgcgtacaa tcaaagacat acccgaattc agctgtacac ggacaccatc
     4561 tttggtaatt tctaatacgg tggcatccat cgcattatta cccgctttca ccttgaggga
     4621 ctgccctacg gtcaatactg aaatatcaga aaccggcgtg tgcttctctt cgcgaggcgc
     4681 acgcggcgct ttcgtcgtcg gtttatcagc gcgaggttta cgttcagcgc cttctttacg
     4741 acgcgctacc gggcgaggtt tacgctcgcg tcgcggcgcg tcttcttttt cgccagccgc
     4801 cgcggcagct tcgcgttttt tcgcttgctg ctctgcgcgc tgcgcctgaa cacgggcttt
     4861 ggcttcttca agctgcttac gcgcatgttc gacatgctgt tcttccagct cgccgcacgg
     4921 attgccatca aggtcgacgc gcgttgcgcc cggcttaacg ccgtacaggt aacgccagct
     4981 tgaagtataa agacgtaaag cggaacgaag ttgcgttttg ctgaggttca tttcgccccc
     5041 aactcgctct accagatcct gaaaaatacc aattttcagc gggcgagctt cgccttccgc
     5101 actaaaacag tgaggaaaac gctcggccag aaacgcgata acttctttac tgctattcaa
     5161 cttaggttga ttttccatga aatttcctga ttacaacgga cgtagccaac aagcagcagg
     5221 catgaacagg cgtcattata atgacgctat cagtaattgc tacgttatcc gttgattatc
     5281 ctgcgacgct cgcaaagaat tttttgtaat ccgtcgttgc aagcacggtt tcaagctgtg
     5341 cgaccagcgt acgcaggccg tgttcatctt cttcggtaaa acggccaaac gccgtgctat
     5401 ctatatccag cacgccgata atccgttcgc caaccgtgac aggcagcaca atttcggcgt
     5461 tgctggcggc atcacaggca atatggccgt caaacgcatg aacatcatca atacgttgaa
     5521 ccttattctg cgctaccgct gcgccgcaca cgccgcgacc aaccggaatc cgcacacagg
     5581 cgattcgccc ctgaaacggc cccaacacca gcgtatcgcc ttcgaggaga taaaatcccg
     5641 cccagttcac ctcggtaaga cgttcgaaca gtagcgcgct ggtattcgcc agcgtggcca
     5701 gaaagctggt ttcacctgcc attaacgact gaaaatcgcg gtttaacgcc gcgtatagtt
     5761 ctgttttgct cattatataa tcacttcgtg gtcttactcc taaacacagg ctattaaaat
     5821 aagcattaaa tgcgttcttg ttcaagatta ttcctgtcat gagttaagat tacattattc
     5881 taacactttg attcacgata catggctctg aacacctcac acgtcacgcc aacaaaaaag
     5941 ctaacgatca ggtcagttag cgaagcgctg ccgcgcagcc actaccagcg ctgccctgaa
     6001 tgcgacatgc tgttcagctt gccggagatg agcgctcatc aaagcgctta ttgtcctcgt
     6061 tgccaggcca aaattcgcga tgggcgcgac tggtcgctga cgcggctgac cgcgatggca
     6121 gtaaccatgc tgctattgat gccgtttgcc tggagtgaac cgctactcca tatctacctg
     6181 ttgggcgtac gcattgatgc caatgtgatg cacggcatct ggcaaatgac gcagcagggc
     6241 gatccgttaa ccgccgcaat ggtgctcttt tgcgtggtgg gcgcgccgct tattctggtt
     6301 ttttcaattg cttacctgtg gtttggcagc cttctcggca tgaatctgcg tccagtcctg
     6361 ctgatgctgg aaaaactgaa agagtgggtg atgctggaca tctatctggt cggtattggc
     6421 gttgcctcta tcaaagtgca ggactatgcc tttctgcagc cgggcattgg gcttttagcg
     6481 ttcgtctcgt tggtggttct tagcattctg actatgattc atctgaatgt ggagcaacta
     6541 tgggaacgat tttatccgca gcaccctgct caacgtgcgg acgaaagatt gcgcgtctgt
     6601 cttggctgcc actttagcgg ctatccggat gcgaaaggac gctgcccgcg ttgtcatatt
     6661 ccgctacggt tacgcagaaa acagagcata cagaagtgtt gggcggcctt gctggcgtct
     6721 attgtctttt tgctgccggc aaacctgctg cctatctcgg taatctacat taatggcggg
     6781 cgtcaggaag atactatcct gtcgggcatt atgtcgcttg ccagcagcaa tatcgccgtc
     6841 gccgccgtcg tttttatcgc cagtattttg gtgccgttta ccaaagtcat cgtgatgttt
     6901 acgctactgt tgagtatcca ttttaaatgc caacagggac tgcggacgcg aattctgttg
     6961 ctgcgtctgg tgacatggat aggccgctgg tcgatgctgg atcttttcgt tatctcgtta
     7021 accatgtctc tgattaatcg cgatcagatt ctggctttta ctatgggacc ggctgcgttt
     7081 tatttcggcg cagcggtaat tttgactatt cttgcagtgg aatggctgga tagccgctta
     7141 ctttgggatg cacatgagtc aggaaacgcc cgcttcgaag actgaagcgc aaattaaaac
     7201 caaacgccgt atttcacctt tctggctgct accgcttatc gcgctaatga tcgcggggtg
     7261 gctggtatgg gatagctacc aggatcgcgg caatagcgtg actatcgatt ttatgtcggc
     7321 ggacggtatc gtaccgggcc gtactcccgt gcgttatcag ggagtagaag tcggcaccgt
     7381 ggaagatgtc agtctgagca aagatctgcg caaaattgaa gttcgcgtca gtatcaaatc
     7441 agatatggaa gatgcgttgc gcgaagagac gcaattctgg ctggtgacgc ccaaagcctc
     7501 gctggcgggc gtttccggcc tggatgcgtt ggtcggcggg aattacatcg gtatgatgcc
     7561 aggtaaaggc aagcccagag atcatttcgt cgccctagat acacagccta aataccggct
     7621 tagcaacggc gatctgatga ttcatctcaa tgcgccggat ctcggttcgc ttaatagcgg
     7681 ttcactggtc tatttccgta aaatccctgt cggacgggtg tatgactatt cgattaaccc
     7741 taacaaacag ggcgtgacga ttgacgttct gattgagcga cggtttaccg atctggtgaa
     7801 aaaaggcagc cgtttttgga atgtctccgg cattgacgcc gatctaagcc tgagcggcgc
     7861 gaaggtgaaa ctggagagcc tcgcggccct ggtcaatggc gcgattgcgt ttgactcacc
     7921 ggacaattcc aaacccgccg cccaggatga cacgttcggc ttatataaag atttagccca
     7981 cagccaacga ggggtaatcg ttaaacttga gctgcccagc ggagacggtc tgaaagcgga
     8041 atctacgccg ctaatgtacc agggactgga ggtgggtgag ctttctaaac tgacgctcaa
     8101 ccctggcggc aaagtcaccg gagagatgac cgtcgatccc agcgttgttc cgctgatgcg
     8161 ggaaaatacg cgtattgagt tacgcaatcc caaactgtcg ctaagtgacg cgaatatcag
     8221 ttcgttgtta accggaaaaa ccttcgagct ggtgccgggc gacggcgaac cacgcagtga
     8281 atttgtggtg gtgccgggtg aaaaagccct gctgcatgag gcgaatgcct taaccctgac
     8341 gctgacggcc ccggaaagtt acggcatcga accgggccag ccgttaattt tacatggcgt
     8401 aaaaattggc caggtcattg agcgcaactt atccagtaaa ggcgtgtcat tcatcgtcgc
     8461 gattgaaccg cagcaccggg atttggtaca gggcgacagt aaattcgtgg tcaacagccg
     8521 ggtggatgtc aaagtcggcc ttgacggcgt agagttcctc ggcgccagcg ccagcgagtg
     8581 gattgacggc ggaattcgta ttttacccgg tacgagcggg aagatgaaat ccacctaccc
     8641 gctctatgct aacctggaaa aagcgctgga aaatagcctc agtgacttac cgactaccac
     8701 cctgacgctg acggccgaaa cgttgccgga tgtccaggca ggttccgtcg tgctgtatcg
     8761 aaaatttgaa gtaggcgaag tcatcaccgt tcgcccacgc gccaatacct ttgacatcga
     8821 cctgcatatt aagccggaat atcgccacct gttaaccagc aatagcgtgt tctgggcgga
     8881 aggcggcgcg aaggtgcaac ttaacggcag cggcctaacg gtacaggcct cgccactctc
     8941 ccgtgcgctg aaaggggcca ttagttttga taacctgagc ggcgccagcg ccagtcggcg
     9001 caaaggcgat aaacgcattc tttatgcttc agaaacttcc gcccgcgcgg taggcggaca
     9061 aattacgcta cacgcgttcg acgccggaaa attggcggag gggatgccca ttcgttacct
     9121 cggtattgat atcggccaga tccagacgct ggaattgatc accgcacgta atgaagtgca
     9181 ggcaaaagcc gtactttatc cggagtacgt gcaaacattt gcccgcgccg ggacacgttt
     9241 ttccgttatt acgccacaaa tctccgcggc gggcgtcgag catctggata cgattctcca
     9301 gccctatatt aacgttgagc caggacgcgg cgcggcgcgg cgcgactttg aactgcagga
     9361 agccacgatt accgactcac gctatctgga tgggttaagc atcgtcgtgg aggcgccaga
     9421 agcaggctcg cttaatattg gcacacccgt cctgtttcgc ggtatcgaag tgggaaccgt
     9481 caccggaatg tccctggggt cgctctccga tcgcgtgatg atcaccttgc gcatcagtaa
     9541 gcgttaccaa tatctggtgc gtaataactc cgtattctgg cttgcctccg gctatagtct
     9601 cgactttggt ctgacaggcg gcgtggtgaa aacggggaca tttaatcaat tcatccgtgg
     9661 cggtatcgcc ttcgctactc caccaggtac gccgctggcg ccaaaagcgc aagccggtaa
     9721 gcatttcctg ttacaagaga gcgaaccgaa agagtggcgt gaatggggta ccgctctgcc
     9781 acgttaaaca ccaggctccg gcgtactcgc gccggagcgt tttatgctac actgcgcgcc
     9841 tgtttttttg ccggcgatac acctgtggct caacacgctg tctattttcc tgacgctttt
     9901 ctgacgcaaa tgcgtgaagc aatgccttcc acgctctctt ttgatgaatt tatttcggcc
     9961 tgccaacgcc cgttgcgccg cagtatacgc atcaatacgc ttaaaatatc cgtggctgat
    10021 ttccttgccc taatcgcgcc ctacggctgg tcgctcacgc caattccgtg gtgtcatgaa
    10081 ggattctgga tcgagcgcga tgatgaagag gcattgccgc ttggcagtac cgctgagcat
    10141 ttaagcggcc tgttttacat tcaggaggcc agttcgatgc tgccggtcgc ggccctgttc
    10201 gccgatgata atcatccgca gcgggtcatg gatatggcag cggcgcctgg ctccaaaacc
    10261 acgcagatcg ctgcccgcat ggggaaccgc ggcgccattc tggccaacga attttcggcc
    10321 agccgcgtca aagttctgca cgctaatatc agccgatgtg gaatcgccaa taccgcactg
    10381 acgcatttcg atggccgcgt atttggcgct gcgttaccgg agatgtttga cgctatcctg
    10441 ctggatgcgc cctgctctgg cgaaggcgta gtacgtaaag atcctgatgc gctaaaaaac
    10501 tggtcgccag aaagtaatct ggatatcgcg gcgacacagc gggaactgct cgacagcgct
    10561 tttcatgctt tacgacccgg cggcacgctg gtctactcca cctgcacgtt aaatcgccag
    10621 gaaaacgaag cggtctgcct ctggctgaaa gagacctacg ccgacgccgt tgaatttttg
    10681 ccgctgggtg atctgtttcc tgacgctgac cgcgccctca ccccggaagg cttcctgcac
    10741 gtcttcccgc aaatttacga ctgcgaagga ttcttcgtcg cacgtctgcg taaaatgtca
    10801 tcccttccag ccatgcccgc gccggggtat aaagtggggg cgtttccttt tacctccctc
    10861 aaaggccgcg aagcattaaa cgttacccag gcggccaacg ccgtcggact gctatgggat
    10921 gaaaatctcc atctttggca gcgtgaaaaa gaggtctggc tgttcccggc agagattgaa
    10981 tcactgatcg gaaaagtccg tttttcccgg ctcggcatta agctggccga aagtcataat
    11041 aaaggctatc gctggcaaca tgaggcgacg atagcccttg cctgcccgac tcatgctcac
    11101 gcgttcgaac tttctgtgca agaggcggag gagtggtatc gcggtcggga tatttatccg
    11161 caaacacccc ctgccgctga tgatgtcctg gtgacgttcc agcatcagcc acttggtctg
    11221 gcaaaacgta tcggcgccag aataaagaac agttacccgc gtgaactggt gcgggatgga
    11281 aaactcttta ctggtaatag ttaaaaggcg cacaaaaaaa ccgcactttt tgactggcgc
    11341 ttttgcgtac gttgactacg ctgaaaaatg gacggctaaa ctggtcgtac cacaattagc
    11401 gtattaacgg agagcacgat gatgaaaacc agtgtgcgca ttggcgcttt tgaaatcgac
    11461 gatgccgaat tacatggcga atcgccgggg gagcgaacgt taacaatccc ctgtaaatcc
    11521 gatccggatt tatgtatgca actggacgcc tgggatgccg aaaccagcgt tcccgccatt
    11581 ctcaacgggg aacattccgt tttgttccgt aatcattacg atcctaaatc tgatgcctgg
    11641 gtcatgcgtc ttgcctgact caaaaagaac ccgtcgccag gcgggttatt tattcttcct
    11701 tttctcattt cccccctgcg ctaacctctc ctacactatc gtgtaaagta gttaacattg
    11761 aggatgtaat gttcgcgctg gtactttttg tatgttacct ggatggagga tgcgaggata
    11821 ttgtcgtgga catctacgat accgagcagc agtgtcttta ttcgatggac gatcaacgga
    11881 ttcgccatgg cggctgtttt ccggtagagg attttatcga cggcttctgg cgacctgcgc
    11941 agcaatatag cgatttttaa ccctagtcgc tgatgccgct attgtatccg cgctaacgtc
    12001 aattgcccgc caaataccgc gcccgtatca atatagtgta tgttggcgaa atccatgcgc
    12061 cgacgcaacg gcgtatggcc aaaccaaaaa tgatcggctc cgctaatccc gccgcgctta
    12121 tttatgagcc gttcgcggct ccagagaacc tgatgtaagt cgaccttttt ttgccattga
    12181 taggttgacg ctggataatc tgcatgagcg atcacatgcg tgctatggcg gcagcgaact
    12241 tccagtatcc agggcagccg ctgacaaaga ataaaaagcg cttcagcttg cgcagcgtgt
    12301 tcagccgtca ggcgggtaaa ccagtcgcca ccattcatca accacagcgt cgactgcgat
    12361 gaggcccgcg catccagcgc catttgttca tgattgccgc gaaccgccgt catccaggac
    12421 tcacgcagta aagccaggca acccaggctg tccgggcctc tatcaatgag atcgcccaca
    12481 gaaactaaca agtcttgttg cggatcaaat tgacactcac gtaacctttt cattaacatt
    12541 gaaaaacagc cgtgaatatc gccgaccacc cagacatgcc gccaattctt tgcctctatt
    12601 cgctgataaa tctcttcagg ccgcatcatg tttttcctgt cgttcattat ccaagataga
    12661 tataaaaaga tagcgtgtgc agattttctt gcttagtaaa cgtgctctgt tgtaaatagc
    12721 gaatttcatc agtagcgagt aaatgctttg ttatcatcgc aataaaatat aactgactgc
    12781 accaggggag tgttatcccc tggcgcagcg agctactcac tatcacctgt tcgcgttcaa
    12841 tattctccct ccttaaaaac atatcggaaa cataaaccac atcacctcag cacacgatat
    12901 agcacactct ttagcggagt gatcctcaag gcaaaccagc gccaatgcag gtgtcgttac
    12961 cgtggcgacc atcgccccca caaacaggcg cagcacaatt ttttttaaag gtggcataac
    13021 ctctcctgac agttaacaga ccattaatcc ttatcgagac atcatccgtg cgcgggtatc
    13081 atagacttaa caacacgcag cgtttcaaaa aaagctgtct ggttataccg gcattta
//
LOCUS       DAJVBX010000130        13031 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.130, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000130 DAJVBX010000000
VERSION     DAJVBX010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 13031)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13031)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13031
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.130"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..932
                     /locus_tag="OPV72_003089"
     CDS             <1..932
                     /locus_tag="OPV72_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF898 family protein"
                     /protein_id="HCR9915317.1"
                     /translation="VSLSFIEHGHPGLGFTLFGLLIAIIPFMAVKGLQYQAMMTSLNG
                     VHFGFQCSMRRAWWYMFALPVLLMVALYIVLYIISLVTIAVGGLVFNIVFLGLLAIIG
                     IGVINGITYSKWMTLFGNGANFGIHRFSIQVNVKTCIRGCVLAMLTLFPFAVVIGYLI
                     APVFTDMILLSMMGNAQAGGALILQYYGQIMACYFLYFLAIIVVTSYLYVALRNLFLN
                     NLSLANDSIRFHSSVTAHGMLWRLLVVFVISGVTLGLAYPWLKIWLVSWLAQNTQVQG
                     DLDSLELTNDEKPLENSPLMWISRGIMPYFPFI"
     gene            complement(1074..3929)
                     /locus_tag="OPV72_003090"
     CDS             complement(1074..3929)
                     /locus_tag="OPV72_003090"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000416368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HCR9915318.1"
                     /translation="MEKTYNPQDIEQPLYEHWEKQGYFKPNGDESKESFCIMIPPPNV
                     TGSLHMGHAFQQTIMDTMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTR
                     HDYGRDAFIDKIWQWKAESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRL
                     YKEDLIYRGKRLVNWDPKLRTAISDLEVENRESKGSMWHIRYPLADGAKTADGKDYLV
                     VATTRPETVLGDTGVAVNPEDPRYKDLIGKFVILPLVNRRIPIVGDEHADMEKGTGCV
                     KITPAHDFNDYEVGKRHALPMINILTFDGDIRESAEVFDTKGEESNVYSSEIPAEFQK
                     LERFAARKAIVAAVDALGLLEEIKPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKP
                     AVEAVENGDIQFVPKQYENMYFSWMRDIQDWCISRQLWWGHRIPAWYDNDGNVYVGRT
                     EDEVRQENNLGADVQLRQDEDVLDTWFSSALWTFSTLGWPENTDALRQFHPTSVMVSG
                     FDIIFFWIARMIMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQKMSKSKGNVIDPL
                     DMVDGISLPELLEKRTGNMMQPQMAEKIRKRTEKQFPNGIEPHGTDALRFTLAALAST
                     GRDINWDMKRLEGYRNFCNKLWNASRFVLMNTEEQDCGFNGGEMTLSLADRWILAEFN
                     QTVKAYREALDNFRFDIAAGILYEFTWNQFCDWYLELTKPVMTGGSESELRGTRHTLV
                     TVLEGLLRLAHPIIPFITETIWQRVKVICGITADTIMLQPFPEYNAAQVDEAALADTE
                     WLKQAIVAVRNIRAEMNIAPGKPLELLLRGCSEEAVRRVNDNRSFLLNLARLESITVL
                     PADDKGPVSMTKIIDGAELLIPMAGLINKEDELARLAKEVAKIEGEIARIEGKLSNEG
                     FVARAPEAVIAKEREKLDGYAEAKAKLIEQQAVISAL"
     gene            complement(3929..4372)
                     /gene="holC"
                     /locus_tag="OPV72_003091"
     CDS             complement(3929..4372)
                     /gene="holC"
                     /locus_tag="OPV72_003091"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004098129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit chi"
                     /protein_id="HCR9915319.1"
                     /translation="MKNATFYLLDNDTTVNGLSAVEQLVCEIAAERWRAGKRVLIACE
                     DEKQAIRLDEALWARPAESFVPHNLAGEGPRGGAPVEIAWPQKRNSSPRDILISLRTS
                     FADFATAFTEVVDFVPYEETLKQLARERYKAYRVAGFNLNTATWK"
     gene            complement(4509..6020)
                     /gene="pepA"
                     /locus_tag="OPV72_003092"
     CDS             complement(4509..6020)
                     /gene="pepA"
                     /locus_tag="OPV72_003092"
                     /EC_number="3.4.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl aminopeptidase"
                     /protein_id="HCR9915320.1"
                     /translation="MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYIS
                     ALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGKERELDERQYKQVIQKTINTLND
                     TGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFN
                     VPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNV
                     ITRVIGEQQMRELGMNAYLAVGHGSQNESLMSVIEYKGNPSEDARPIVLVGKGLTFDS
                     GGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELKLPINVIGVLAGCENMPGGRAYRP
                     GDVLTTMSDQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHI
                     TGLMSNHNPLAHELIGASEQAGDRAWRLPLGDEFQEQLESNFADMANIGGRPGGAITA
                     GCFLSRFTRKYNWAHLDIAGTAWRSGKAKGATGRPVALLSQFLLNRAGFNGEE"
     gene            6415..7515
                     /gene="lptF"
                     /locus_tag="OPV72_003093"
     CDS             6415..7515
                     /gene="lptF"
                     /locus_tag="OPV72_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptF"
                     /protein_id="HCR9915321.1"
                     /translation="MIIIRYLVRETLKSQLAILFILLLIFFCQKLVRILGAAVDGDIP
                     ANLVLSLLGLGVPEMAQLILPLSLFLGLLMTLGKLYTESEITVMHACGLSKAVLVKAA
                     MVLALFTGILAAVNVMWAGPWSSKHQDEVLAEAKANPGMAALAQGQFQQATNGSSVLF
                     IESVDGSDFHDVFLAQIRPKGNARPSVVVADSGHLTQLRDGSQVVTLNKGTRFEGTAL
                     LRDFRITDFQNYQAIIGHQAVALDPNDTDQMDMRTLWNTDNDRARAELHWRITLVFTV
                     FMMALMVVPLSVVNPRQGRVLSMLPAMLLYLLFFLIQTSIKSNGGKGKLDPVIWMWAV
                     NLIYLALAIGLNLWDTVPVRRLRARFLRKGAV"
     gene            7515..8597
                     /gene="lptG"
                     /locus_tag="OPV72_003094"
     CDS             7515..8597
                     /gene="lptG"
                     /locus_tag="OPV72_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptG"
                     /protein_id="HCR9915322.1"
                     /translation="MQPFGVLDRYIGKTIFTTIMMTLFMLVSLSGIIKFVDQLKKAGQ
                     GNYDALGAGMYTLLSVPKDIQIFFPMAALLGALLGLGMLAQRSELVVMQASGFTRMQV
                     ALSVMKTAIPLVLLTMAIGEWVAPQGEQMARNYRAQAMYGGSLLSTQQGLWAKDGNNF
                     VYIERVKGDEELAGISIYAFNDQRRLQSVRYAASAKFDPEHKVWRLSQVDESDLQNPK
                     QITGSQTVSGTWKTNLTPDKLGVVALDPDALSISGLHNYVKYLKSSGQDAGRYQFNMW
                     SKIFQPLSVAVMMLMALSFIFGPLRSVPMGVRVVTGISFGFVFYVLDQIFGPLTLVYG
                     IPPIVGALLPSASFFLISLWLMLRKS"
     gene            complement(8803..9801)
                     /locus_tag="OPV72_003095"
     CDS             complement(8803..9801)
                     /locus_tag="OPV72_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCR9915323.1"
                     /translation="MRNHRISLQDIATLAGVTKMTVSRYIRSPKKVARETGERIAQIM
                     EEINYIPNRAPAMLLNAQSYTLGVLIPSFQNQLFADILAGIESVTSGHNYQTLIANYN
                     YNRDSEEESVINLLSYNIDGIILSEKYHTLRTVKFLRSATLPIVELMDIQGDRLDMEV
                     GFDNRQAAFDMVSTMLDKRQRRKILYLGSKDDIRDEQRYHGYCDAMTRRGLAPLRINP
                     RAISSIHLGIQLMRDALTAHPDVDGVFCTNDDIAMGALLWCRERQLAVPEQISIAGFH
                     GLEMGRQMIPSLASVITPRFEIGRRAAQMLLNKIKNNDLNHNTIDLGYQIYHGNTL"
     gene            complement(9865..10989)
                     /locus_tag="OPV72_003096"
                     /pseudo
     CDS             complement(9865..10989)
                     /locus_tag="OPV72_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463342.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
     gene            complement(10984..11355)
                     /locus_tag="OPV72_003097"
                     /pseudo
     CDS             complement(10984..11355)
                     /locus_tag="OPV72_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463346.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
     gene            11578..11662
                     /locus_tag="OPV72_003098"
     tRNA            11578..11662
                     /locus_tag="OPV72_003098"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11612..11614,aa:Leu,seq:caa)
     gene            11826..>13031
                     /locus_tag="OPV72_003099"
     CDS             11826..>13031
                     /locus_tag="OPV72_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase arm-type DNA-binding domain-containing
                     protein"
                     /protein_id="HCR9915324.1"
                     /translation="MKLNARQVETAKPKDKTYKMADGGGLYLEVSAKGSKYWRMKYRR
                     PSDKKEDRLAFGVWPTVTLAQARAKRDEAKKLLVQGIDPKTEQKEAQAENSGAYTFET
                     IAREWHASNKRWSEDHRSRVLRYLELYIFPHIGSSDIRQLKTSHLLAPIKKVDASGKH
                     DVAQRLQQRVTAIMRYAVQNDYIDSNPASDMAGALSTTKARHYPALPSSRFPEFLARL
                     AAYRGRVMTRIAVELSLLTFVRSSELRFARWDEFDFDKSLWRVPAKREEIKGVRYSYR
                     GMKMKEEHIVPLSRQAMVLLEQLKQISGDKELLFPGDHDATKVMSENTVNSALRAMGY
                     DTKTEVCGHGFRTMARGALGESGLWSDDAIERQLSHSERNNVRAAYIHTSEHLDERRL
                     MVQWWADYLD"
BASE COUNT         2838 a         3419 c         3569 g         3205 t
ORIGIN      
        1 ttgttagcct ctcttttatt gaacacggtc atcccggtct cggttttacg ctattcggct
       61 tattaattgc gattattcct tttatggcgg tgaaaggatt acagtatcag gcgatgatga
      121 cttcgcttaa tggcgtacat tttggattcc agtgttccat gcggcgcgcc tggtggtaca
      181 tgttcgctct tccggtactc ctgatggtgg cgctttatat tgttctttat attatctcac
      241 tggtaaccat cgccgtcggc ggtttagtgt tcaatatcgt ttttctcggt ttgctggcta
      301 ttattgggat aggggtcatt aacggtatta cctacagcaa atggatgacc ttgtttggca
      361 atggcgcaaa ctttggcatt catcgtttct cgattcaggt taatgttaaa acgtgcatca
      421 gagggtgcgt gttggcaatg ttgacccttt ttccttttgc tgtcgtgatt ggttatctaa
      481 tcgcgccggt gttcaccgac atgattcttt tgagtatgat ggggaatgcg caggcaggag
      541 gggcgcttat tctgcaatat tatggccaga taatggcatg ttatttcctc tattttctcg
      601 cgattattgt ggtaaccagt tacttatatg tggcgttacg caacctgttt ttaaacaatt
      661 tgtcactggc gaacgattcg attcgttttc attcctctgt cactgcacac ggtatgctgt
      721 ggcggttact ggtggtgttt gtgatttccg gcgtgacctt agggctggct tatccgtggt
      781 tgaaaatttg gctggtgagc tggctggcgc agaatacaca ggtccagggc gatctggatt
      841 cgcttgagtt aaccaatgat gagaagccgc tggaaaacag cccgctaatg tggatttctc
      901 gtggcatcat gccttacttc ccgtttatct gatgtaaaaa ggccgacgtt tacgtcggcc
      961 cataattcat gttgtcggat ggtggcgtga atgccttatc cggcctaccg atcgcgccat
     1021 gtcaataagc gaacgtgtag gcctggtaag cgaagcgcca tcaggctttc agattacagc
     1081 gcgctaataa ccgcctgctg ctcaatcagc ttcgctttgg cttctgcata accgtccagc
     1141 ttctcacgct ctttggcgat caccgcttcc ggcgcgcggg caacgaaacc ttcgttggac
     1201 agtttgcctt cgatacgggc aatctcgcct tcgattttcg ccacttcttt cgccagacgc
     1261 gccagctcat cttctttgtt gatgaggccc gccatcggga ttagcagttc ggcaccgtcg
     1321 atgattttgg tcatggaaac cggacctttg tcatcggctg gcagcacggt gatgctttcc
     1381 agacgcgcca ggttcagcag gaagctacgg ttgtcgttaa cacgacgaac ggcttcttca
     1441 ctacagccgc gcagcagcag ttccagcggt ttgcccgggg cgatgttcat ttccgcacga
     1501 atgttacgta cggcaacgat cgcctgcttc agccactcgg tatcggccaa cgcggcttca
     1561 tccacctgcg cggcgttata ttccgggaac ggctgcagca taatggtatc ggcggtaatg
     1621 ccacagataa ccttcacgcg ctgccagatg gtttcggtga tgaacggaat gatcgggtgc
     1681 gccagacgca gcaaaccttc cagcacggtg accagcgtat ggcgggtgcc acgcagttca
     1741 gactcggaac ccccggtcat taccggtttg gtcagctcca gataccagtc gcagaactgg
     1801 ttccaggtga actcgtacag gatgcctgcg gcgatatcga agcggaagtt atccagtgct
     1861 tcgcggtagg ctttaacggt ctggttgaat tccgccagga tccagcggtc cgccagcgac
     1921 agggtcattt cgccgccgtt gaagccgcaa tcctgctctt cagtgttcat cagcacaaag
     1981 cggctggcgt tccacagctt gttacagaag ttacggtagc cttccagacg cttcatatcc
     2041 cagttgatgt cgcggccggt cgaggctagc gccgccaggg taaagcgcag ggcgtcggtg
     2101 ccgtgcggct cgatgccgtt cgggaactgc ttctcggtac gcttgcggat tttctccgcc
     2161 atctgcggct gcatcatgtt gccggtgcgt ttctccagca gttccggcag ggagatgccg
     2221 tccaccatat ccagcgggtc gataacgtta cccttggatt tggacatctt ctggccttcg
     2281 tcgtcgcgaa tcagaccggt catgtagaca gtatggaacg gcacctgcgg cttgccgttt
     2341 tcatctttga tgaagtgcat ggtcatcatg atcatgcggg caatccagaa gaagatgata
     2401 tcgaagccgg acaccatcac gctggtggga tggaactgac gcagggcgtc ggtgttttct
     2461 ggccagccga gggtggagaa ggtccacagc gcggaggaga accaggtatc aagaacgtct
     2521 tcgtcctgac gaagctgaac gtcggcaccg aggttatttt cctgacgcac ttcgtcttcg
     2581 gtacggccaa cgtagacgtt gccgtcgttg tcataccatg ccgggatacg gtgaccccac
     2641 cacagctgac gagagataca ccagtcctga atatcgcgca tccaggagaa gtacatgttt
     2701 tcgtactgct tcggcacgaa ctgaatgtcg ccgttttcaa ccgcttccac cgccggtttc
     2761 gccagcacgt ctgcacggac gtaccactgg tcggtcagca tcggttcgat aactacgccg
     2821 ccacggtcgc cgtaagggac ggtcagatcg tgcggtttaa tttcttccag caggcccagc
     2881 gcgtcaacgg cagcaacgat ggccttacgg gcagcaaagc gttccagctt ctggaactca
     2941 gccggaatct cgctggaata aacgttagac tcttcacctt tggtatcgaa cacttccgcg
     3001 ctttcgcgaa tgtcgccatc aaaggtcagg atgttgatca tcggcagggc gtgacgtttc
     3061 ccgacttcat agtcgttaaa gtcgtgcgcc ggggtgatct tcacgcagcc ggtacctttt
     3121 tccatatcgg cgtgttcgtc gcccacaatc ggaatgcggc ggttaaccag cggcagaata
     3181 acgaatttgc caataagatc cttataacgc ggatcttccg ggttcacggc cacgccggta
     3241 tcgcccagta cggtttccgg acgggtggtg gcgacgacca ggtaatcttt accgtctgcg
     3301 gttttcgcgc cgtcggccag cggatagcgg atgtgccaca tcgagccttt ggactcgcgg
     3361 ttttccactt ccaggtcaga gatggcggtg cgcagcttcg gatcccagtt caccaggcgt
     3421 ttgccacggt aaatcaggtc ttctttgtac aggcggacaa agacttcttt cacggcattg
     3481 gaaaggcctt cgtccatggt gaagcgctcg cgctcccagt caacggagtt gccgagacgg
     3541 cgcatctgac gggtaatggt gccgccggat tccgctttcc actgccagat tttgtcgata
     3601 aacgcatcgc ggccgtagtc gtgacgggtt ttaccttctt cagcggcaat cttgcgctca
     3661 accaccatct gggttgcgat cccggcgtgg tcggtgccga cctgccacag ggtgttttta
     3721 ccctgcatac gctggtaacg gatcatggta tccatgatgg tttgctggaa agcatgtccc
     3781 atatgcaaac tgccggtgac gttcggcggc gggatcatga tgcagaagga ctctttgctt
     3841 tcgtcgccgt taggcttgaa atagccctgc ttttcccagt gctcgtaaag cggctgttcg
     3901 atatcttggg ggttatatgt cttttccatt atttccaggt tgccgtattc aggttaaaac
     3961 cagccacgcg gtaggctttg tagcgttcgc gcgccagttg tttcaaagtt tcttcgtaag
     4021 ggacgaagtc taccacttct gtgaaagcgg tggcaaaatc tgcaaagctt gtacgcaggc
     4081 tgattaaaat atcgcgcggg ctgctgttgc gtttttgcgg ccaggcgatt tcaaccggcg
     4141 cgccgccgcg tgggccttcg cctgccagat tgtgcgggac aaaactttcc gccggtcttg
     4201 cccacagcgc ttcatccagc cgaatggcct gcttctcatc ttcgcaggcg atcagcacgc
     4261 gcttgccagc gcgccaacgt tctgcggcaa tttcacacac cagttgttca acggcgctta
     4321 aaccgttgac ggtggtgtca ttgtccagaa gatagaacgt cgcattcttc atatatgagg
     4381 cttcttgtgg tggatttaaa tgcgttgcca tgatgcaccc cgtaggccgg ataagcgtgg
     4441 cgccatccgg caaaacgcct gatggtggcg ctaatgcgcc ttatcaggcc tacggggtaa
     4501 tctcaaactt actcttcgcc gttaaagccc gcacgattga gcaggaactg cgacagcagc
     4561 gctaccggac gaccggtggc acctttggct ttaccggaac gccaggcggt accggcgata
     4621 tccaggtgcg cccagttgta cttacgggta aagcgcgaca ggaagcagcc cgcggtgata
     4681 gcgccgccag gacgaccacc aatgttcgcc atatccgcaa agttggactc cagttgttcc
     4741 tggaactcat cgcccagcgg cagacgccac gcgcggtcgc ccgcttgctc ggacgcgccg
     4801 atcagttcat gcgccagcgg gttatggttc gacatcagac cggtaatgtg atggcccagc
     4861 gcaatcacgc aggcgccggt tagcgtcgcg acgtcaatga ccgcttccgg ttcgaagcgc
     4921 tcaacgtagg tcagcacgtc gcacaaaacc agacggcctt cggcgtcggt gttcaggact
     4981 tcaacggttt gatcagacat agtggtcagc acgtcgccag ggcgataagc gcgtccgccc
     5041 ggcatgtttt cacagcccgc cagtacgccg ataacgttaa tcggaagctt aagctcggcg
     5101 accatacgca tcacgccgta aaccgccgcc gcgccgcaca tgtcgtactt catctcgtcc
     5161 atcccttcag atggcttgat ggagatgccg ccggagtcga aggtcaggcc tttacctacc
     5221 agcacgatcg ggcgcgcgtc ttcggacgga ttgcccttgt actcaatcac cgacatcagc
     5281 gattcattct gcgaaccgtg gccgaccgcc agataagcgt tcatacccag ttcgcgcatt
     5341 tgctgttcgc cgatcacgcg ggtgatgaca tttttgctgt agctgtcggc caactggcgc
     5401 gcctgtgacg ccaggtaggc ggcgttacag atattgggcg gcatgttgcc gagatctttc
     5461 gcagccttaa tcccggcggc gatggccaga ccgtgctgaa tggcgcgttc gccgctggtg
     5521 agctcacggc gggtcggcac attaaagacc atcttacgta gcgggcggcg cggctcgctc
     5581 ttgttggtct tgagttgatc aaagctataa agcgtctctt tggccgtttc gacggcctga
     5641 cgcactttcc agtagttgtt gcggccttta acgtgcagtt cggtcaggaa acagacggct
     5701 tccatcgaac cagtatcatt cagagtattt atcgttttct gaataacctg cttatactga
     5761 cgttcatcaa gctcgcgctc tttgccgcaa ccaatgagga ggattcgctc ggaaagaacg
     5821 ttaggaacat ggtgcagcaa cagagtctgc cccggttttc cttccagttc gccgcgacgc
     5881 agcaatgcgc tgatgtatcc gtcgctaatt ttgtcgagct gttctgcaat cggagaaagg
     5941 cgacgcggtt caaagacgcc cacgacaatg caggcactcc gctgtttctc cgggctaccg
     6001 ctttttacac tgaactccat gcactatgct cctgaatctt aaagacaaca gtggtggcta
     6061 cagctatact cgtcgtcttt caagttgcag atgcgttggc tgcgcctgct cacccctgtc
     6121 gcttacctga tgtaagctcc ggggctccac agtcctgccg cctgcctgca actcgaaatc
     6181 cattagagta tagaaattga aagctttcgt aactcatatc cgctgttgcg gtgacttcgt
     6241 gttaatctta acgttattac ggcattggca cgtcagaaca agttctgaga ggtgaatccg
     6301 ctgagtataa tgatcttagc gatgatttcg acgactcaag agaataaatg acgtttaagc
     6361 catgaaacaa gctaaattcc agcaaaaaaa tggtttttta cgggcgtatt taaagtgata
     6421 atcataagat atctggtgcg ggagacgctc aaaagccagc tggcgatact cttcatctta
     6481 cttttgatct tcttttgtca aaagttagtg aggattctcg gcgcggcggt tgacggcgat
     6541 attcccgcaa atctggtgct ctcgcttctg gggctgggcg taccggaaat ggcgcagctc
     6601 atcctgcctt taagcctgtt cctggggctg ctgatgacgc tgggcaaact gtataccgaa
     6661 agtgaaatta cggtcatgca cgcctgtggg ttgagcaaag ccgtgctggt aaaggccgcc
     6721 atggtactgg cgttatttac cggtatcctt gcggcggtta acgtgatgtg ggccggcccc
     6781 tggtcgtcaa aacaccagga tgaagtgctg gcggaggcga aagcgaaccc cggtatggcg
     6841 gcgttggcgc aggggcaatt ccagcaggcg accaacggca gctcggtgct gtttatcgaa
     6901 agcgttgacg gcagcgactt ccacgatgtt ttcctggcgc aaattcgtcc taagggcaat
     6961 gctcgtcctt ctgtggtagt ggccgattcc ggacacctta ctcagttgcg cgatggttcc
     7021 caggttgtca ccttaaacaa agggacgcgt tttgaaggga cggcgttgct acgcgatttt
     7081 cgcatcaccg acttccagaa ctatcaggcg attattggtc atcaggccgt ggcgctggac
     7141 ccgaacgata ccgaccagat ggacatgcgc acgctgtgga ataccgacaa cgatcgcgct
     7201 cgcgccgagc tgcactggcg tatcacgtta gtctttaccg tatttatgat ggcgctgatg
     7261 gtcgtgccgc tcagcgtggt gaatccacgt caggggcgcg tcttgtctat gttgcccgct
     7321 atgctgcttt atctgctgtt cttcctgatc cagacctcca ttaaatcgaa tggcggtaaa
     7381 ggcaaactgg acccggttat ctggatgtgg gcggtcaacc tgatctatct ggcgttggcg
     7441 attggtttaa acctgtggga tacggtgccg gttcgccgcc tgcgtgcccg ttttctgcgt
     7501 aaaggagcgg tataatgcag ccatttggtg tgcttgaccg ctatatcggt aaaaccattt
     7561 ttaccaccat catgatgacg ttgttcatgc tggtgtcgct ctccgggatc atcaagtttg
     7621 tcgatcagct gaaaaaagcg gggcagggta actacgacgc gctgggcgcg ggtatgtaca
     7681 ccctgctcag cgtacctaag gatatccaga tcttctttcc tatggcggcg ctgcttggcg
     7741 cgctgctggg gctggggatg ctggcgcagc gtagcgaact ggtggtgatg caggcatcgg
     7801 gtttcacccg tatgcaggtg gcgctgtcgg tgatgaaaac ggctatcccc ctggtgctgt
     7861 taaccatggc gatcggcgaa tgggtcgccc cgcagggcga gcagatggcg cgtaactatc
     7921 gtgcgcaggc gatgtatggc ggctcgctgc tttccaccca gcaaggtctg tgggcgaaag
     7981 acgggaataa ctttgtctat attgaacggg tgaagggcga cgaggagctg gccggcatta
     8041 gtatttacgc tttcaacgat cagcgtcgtt tgcagtcggt gcgttacgcc gcttcggcaa
     8101 aattcgaccc ggagcataag gtctggcgtt tgtcgcaggt ggatgagtcc gatctgcaaa
     8161 acccgaaaca gatcaccggt tcgcagacgg tgagcggcac ctggaaaacg aatctgacgc
     8221 cggataagtt aggcgtggtg gcgctggacc cggatgcgct ttccatcagc ggtctgcata
     8281 actacgttaa atatctgaag tcgagcggac aggacgctgg acgttatcag ttcaatatgt
     8341 ggagtaaaat cttccagccg ctctccgtgg cggtgatgat gctgatggcg ctgtcgttta
     8401 ttttcgggcc gctacgtagt gtgccgatgg gcgtgcgtgt ggtgacgggg attagcttcg
     8461 gcttcgtctt ttacgtcctc gaccagattt ttggcccgct gacgctggta tacggcattc
     8521 cgccgattgt cggcgctctg ctgccgagcg cgtctttctt cctgattagc ctgtggctaa
     8581 tgctgcgtaa gtcgtaatca cagtaatcgt aggcctgatg gcgctgtgct tttcaggcct
     8641 actccggacc cgtaggccgg ataaggcgtt agcgccgcca tccggcagac agcttggtat
     8701 tcctcgaatg atgtagcgcg taacctgacg cgtggcgctt ttggctacgc gttaagcaca
     8761 ggcaagctgc gggaaagagc ataagcgcag tagttcaaaa agttataatg tgttgccgtg
     8821 ataaatctga taacccaaat caatcgtatt atggttgaga tcgttatttt taattttgtt
     8881 gagcaacatc tgcgcggctc tgcgcccgat ctcaaaacga ggggtaatta cgctggcgag
     8941 gctcggtatc atttgcctgc ccatctccag accgtggaag ccggcgatgg agatctgctc
     9001 cggtacggcc agttgacgct cgcggcacca cagtagagcg cccattgcga tatcgtcatt
     9061 tgtacaaaag acgccatcca cgtccgggtg cgcagtaagc gcatcacgca ttagctgtat
     9121 ccccagatgg atagaggaga tagcgcgggg attgatgcgc aacggcgcca gcccccggcg
     9181 cgtcatcgca tcgcagtagc cgtgataacg ctgctcatca cggatatcgt cttttgaacc
     9241 cagatagaga attttccgcc gctggcgttt atccagcatg gtgctgacca tatcaaaggc
     9301 ggcctgacgg ttatcaaacc ccacctccat atctaagcga tcgccctgga tatccatgag
     9361 ttctacaatc ggaagggtag ctgagcgcag gaatttgacg gttctgaggg tatgatattt
     9421 ttctgaaaga ataatgccgt cgatattgta agacagtaaa ttgataacgg actcttcttc
     9481 cgaatcgcga ttgtaattgt aattcgcaat gagagtttgg tagttatgac ccgacgttac
     9541 ggattcaatc ccggcgagaa tgtcggcaaa caactgattc tgaaaagagg ggatcagcac
     9601 gcccagagtg taactttgcg cgtttaacag catagcaggc gcgcgatttg gtatgtagtt
     9661 aatttcctcc atgatctgcg caatacgctc gccggtttcc ctggcgactt ttttcggcga
     9721 gcggatgtaa cggctcaccg tcatttttgt cacgccagca agcgtagcga tatcctgcaa
     9781 agaaattctg tgattcctca tgttttctcc agtaccgggg gcgggaacgt cgcccccatg
     9841 gttaattggg ctgcggatga tgaattaatg cagaaccgca ttcagcgcca gtacgcccag
     9901 caaccccatg acagaaatca atgtttccat aacggtccag gtgcgtaggg tttccccgac
     9961 gctaagatta aaataccctt taaacagcca aaaaccggga tcgttaacat gtgatgcaat
    10021 aacgcttccc gcgcctgtcg ccagtaccat taacgccgga tcggcgtggg ttacgttaat
    10081 aatcggcaat acgacgcccg ctgtggttat cgcggccacg gtcgcggaac ctaacgcaat
    10141 acgcagcacg gcggctaccg tccagcacat taataacgga gatagcgagg tgccggtcat
    10201 taattgcgag atatattgac ccacgccgct atccaccagc acttgcttaa acgcgccgcc
    10261 gcccgcgatg ataaaaacaa tcatcgcaat agcgccaatg gactcgccga cgatatccat
    10321 cacctgctca accgtacgtc cattgcgtcg ccccagcgta aaaatggcga tgataatggc
    10381 aataaacaac gccactgctg gattaccgat aaattcgaag aaaacccgca cggcattcgt
    10441 ttttggcagc gtgatttcac ataccgctgc gatggccatc agaatgaccg ggatcacggc
    10501 ggcaaaaata ctgttccaga atgacggcat ctcctcttca ctgaatagat gaggattaaa
    10561 taatccttca ggcggcgctt tttcaaatcg cgccagcaat tttgaaaaca gagggccggc
    10621 aacaatcacg gtcggtatgg taatgattaa cccatacagc agggtcgtac cgagatttgc
    10681 ctcaaaaatt gtcgcaatag cggtagggcc gggatgcggc ggcaggaagc agtgcgtaac
    10741 ggataaggcg gcgaccattg gaaccccgac atacagcaat ggcagtcccg atgaggccac
    10801 aattgtaaaa acgagcggca acagcagtac gaatccgact tcaaaaaaca ttgccaggcc
    10861 gacgataagc ccggtgatca ccagcgccca ttgcacgcgt tttttgccga acgtattaat
    10921 gagcgtcgtc gcaatgcgct gcgcggcgcc ggtatcggaa attaatcttc ccagcatcgc
    10981 gccaaaaccg ccacgattga ggatagtggg cactgcccct tccaggcagt taatttgatt
    11041 gccgctgata caggcatcgc agtgtccgca gctgcgcgcc gtccagccga ttccaacgcg
    11101 ctggccgact tttagtccct tatcctgtgc cgcgctaccg agtgcggcca cccgaccgat
    11161 gacctcgtgt ccggcaacca gagggtattg agagaacccc cattcattgt cgatcatcga
    11221 cagatcggaa tggcagatcc cgcagtagtc gacccgtacc tcgacatctt ccggttggag
    11281 ttctcccgcg tcatattcat agagttcgag ctcgccgccc gcctctttgg cggcgtagct
    11341 ttttattatc gtcattgtgc ttcccttaat gtggtgttga actgaaaagt gtagagcatg
    11401 gaggcaaggg acgcccggcg ttaatctgct ggagaaggcg ggaagtagcc tgattattct
    11461 atttaatcct caacgctgct gaaattttca gcacttagcg atacaggtgt atgctcgtgc
    11521 ttgcatggcg gcgtatgaca ggtataatcc acaacgtttt ccgcatacct cttcagtgcc
    11581 gaagtggcga aatcggtaga cgcagttgat tcaaaatcaa ccgtagaaat acgtgccggt
    11641 tcgagtccgg ccttcggcac cattagtact tccaagacca tccgagaaag tccaattatc
    11701 ccttaaaaat caatgattga agcgattttt acgtcctgag tcgtccgagg ttgtccgttg
    11761 aaatccggaa gtcattgggg gcataattgg gggcatctta acttcgatta gaaatgtgcc
    11821 cccaaatgaa gctcaacgcc agacaggtcg agaccgcaaa gccaaaagac aaaacctaca
    11881 aaatggccga tggcggcggt ttgtaccttg aggtttcggc caagggatcc aaatactggc
    11941 gcatgaaata cagacgcccc tctgacaaaa aagaggatcg cctcgctttt ggtgtttggc
    12001 ctactgtgac acttgctcag gcaagagcaa agcgcgatga agccaaaaag ttgctagtgc
    12061 agggcattga tccaaaaacc gaacagaaag aggctcaggc cgagaactcg ggggcgtata
    12121 ctttcgaaac tatcgctcgt gaatggcatg ccagtaacaa gcgctggagc gaagaccatc
    12181 gatcgcgcgt tcttcgctat cttgaacttt atattttccc tcatatcggt tcgtccgaca
    12241 ttcgccagct caaaaccagt cacctgttag ccccgatcaa aaaagttgat gccagtggta
    12301 aacacgacgt cgctcagcgc ctgcaacagc gcgtcacggc tattatgcgt tatgccgtac
    12361 agaacgatta catcgactct aatccagcca gtgacatggc cggtgcgtta tcgactacca
    12421 aagcacgaca ctatccagcc ttaccttcta gccgtttccc tgagtttctt gctcgccttg
    12481 ctgcatatcg tggccgtgta atgacacgga ttgctgtcga gctttcctta ctaacttttg
    12541 tacgttccag cgagttacgt ttcgcgcgtt gggacgagtt cgacttcgat aaatcccttt
    12601 ggcgcgtacc ggcaaaacga gaagaaatta agggtgtgcg ttattcgtac cgtggcatga
    12661 agatgaaaga ggagcatatc gttcctctca gtcggcaggc gatggttttg ttagagcagc
    12721 tcaagcagat tagtggtgat aaagagctgt tgtttccggg ggatcacgac gcaactaagg
    12781 ttatgagcga aaacacggta aatagcgcat tgcgtgcgat gggttatgac acaaaaaccg
    12841 aggtctgcgg gcatgggttt cggacgatgg cgcgtggtgc tttgggtgag tcaggattat
    12901 ggagcgatga cgcgatagag cgtcagttaa gccattctga gcgtaacaat gtgcgtgctg
    12961 cctatattca cacttcagag catttggatg agcgtcgttt gatggtgcag tggtgggctg
    13021 attatctcga t
//
LOCUS       DAJVBX010000131        13016 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.131, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000131 DAJVBX010000000
VERSION     DAJVBX010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 13016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13016
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.131"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(163..918)
                     /locus_tag="OPV72_003100"
     CDS             complement(163..918)
                     /locus_tag="OPV72_003100"
                     /EC_number="3.6.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol diphosphatase"
                     /protein_id="HCR9915325.1"
                     /translation="MKKTGYFLLAVIVIVAAAGVGYWKFSGNPDALREIVLERCLPDQ
                     LQHQNPAPCAEVKPRAGYVIFKDRHGPLQYLLMPTYRINGTESPLLLEPATPNFFWLA
                     WQARGYMSKKYGHDIPDSAVSLAINSRLGRSQDHLHIHISCIRPDVREQLDNDLTRIS
                     TRWLPLPGDLMGHEYLARRVTESELAQRSPFMMLAEEVPEARDHMGRYALAVVRQSDD
                     SFVLLATERNLLTLNRASAEEIQDHSCAILSSR"
     gene            complement(1019..2008)
                     /locus_tag="OPV72_003101"
     CDS             complement(1019..2008)
                     /locus_tag="OPV72_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate ABC transporter substrate-binding
                     protein"
                     /protein_id="HCR9915326.1"
                     /translation="MKKWGVGFTLLLASTSILAKDIQLLNVSYDPTRELYEQYNKAFS
                     AHWKQETGDNVVIRQSHGGSGKQATSVINGIEADVVTLALAYDVDAIAERGRIDKNWI
                     KRLPDNSAPYTSTIVFLVRKGNPKQIHDWNDLIKPGVSVITPNPKSSGGARWNYLAAW
                     GYALHHNNNDQAKAQDFVKALFKNVEVLDSGARGSTNTFVERGIGDVLIAWENEALLA
                     TNELGKDKFEIVTPSESILAEPTVSVVDKVVEKKGTNAVAEAYLKYLYSPEGQEIAAK
                     NFYRPRDADVAKKYDDAFPKLKLFTIDEVFGGWVKAQKDHFANGGTFDQISKR"
     gene            complement(2212..3174)
                     /gene="pfkA"
                     /locus_tag="OPV72_003102"
     CDS             complement(2212..3174)
                     /gene="pfkA"
                     /locus_tag="OPV72_003102"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014072359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HCR9915327.1"
                     /translation="MIKKIGVLTSGGDAPGMNAAIRGVVRAALTEGLEVMGIYDGYLG
                     LYEDRMVQLDRYSVSDMINRGGTFLGSARFPEFRDENIRAVAIENLKKRGIDALVVIG
                     GDGSYMGAKRLTEMGFPCIGLPGTIDNDIKGTDYTIGYFTALGTVVEAIDRLRDTSSS
                     HQRISIVEVMGRYCGDLTLAAAIAGGCEFIVVPEVEFNREDLVAEIKAGIAKGKKHAI
                     VAITEHMCDVDELAHFIEKETGRETRATVLGHIQRGGSPVPYDRILASRMGAYAIDLL
                     LEGHGGRCVGIQNEQLVHHDIIDAIENMKRPFKSDWMECAKKLY"
     gene            complement(3359..4255)
                     /gene="fieF"
                     /locus_tag="OPV72_003103"
     CDS             complement(3359..4255)
                     /gene="fieF"
                     /locus_tag="OPV72_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462942.1"
                     /note="FieF, a metal efflux transporter, is a member of
                     the CDF (cation diffusion facilitator) family of
                     transporters; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family cation-efflux transporter FieF"
                     /protein_id="HCR9915328.1"
                     /translation="MNQTYGRLVSRAAIAATAMASALLLIKIFAWWYTGSVSILAALV
                     DSLVDIAASLTNLLVVRYSLQPADDEHTFGHGKAESLAALAQSMFISGSALFLTSIQN
                     LIKPTPMNDPGVGIGVTVIALICTIILVTFQRWVVRKTQSQAVRADMLHYQSDVMMNG
                     AILIALGLSWYGWHRADALFALGIGIYILYSALRMGYEAVQSLLDRALPDAERQEIID
                     IVTSWPGVSGAHDLRTRQSGPTRFIQIHLEMEDNLPLVQAHFVADQVEQAILRRFPGS
                     DVIIHQDPCSVVPREGRKFELV"
     gene            complement(4403..4903)
                     /gene="cpxP"
                     /locus_tag="OPV72_003104"
     CDS             complement(4403..4903)
                     /gene="cpxP"
                     /locus_tag="OPV72_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell-envelope stress modulator CpxP"
                     /protein_id="HCR9915329.1"
                     /translation="MRKVTAAVMASTLAFSFLSHAAEVVTSDNWHPGDGATQRSAQNH
                     MFDGISLTEHQRQQMRDLMQQARHEQPPVNVSEMETMHRLVTAEKFDESVVRAQAEKM
                     AQEQVARQVEMARVRNQMYRLLTPEQQAVLNEKHQQRMEQLRDVAQWQKSSSLKLLSS
                     SNSRSQ"
     gene            5054..5752
                     /gene="cpxR"
                     /locus_tag="OPV72_003105"
     CDS             5054..5752
                     /gene="cpxR"
                     /locus_tag="OPV72_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response regulator transcription
                     factor CpxR"
                     /protein_id="HCR9915330.1"
                     /translation="MNKILLVDDDRELTSLLKELLEMEGFNVLVAHDGEQALELLDDS
                     IDLLLLDVMMPKKNGIDTLKALRQTHQTPVIMLTARGNELDRVLGLELGADDYLPKPF
                     NDRELVARIRAILRRSHWSEQQQSSDNGSPTLEVDALSLNPGRQEASFDGQTLELTGT
                     EFTLLYLLAQHLGQVVSREHLSQEVLGKRLTPFDRAIDMHISNLRRKLPERKDGHPWF
                     KTLRGRGYLMVSAS"
     gene            5749..7122
                     /gene="cpxA"
                     /locus_tag="OPV72_003106"
     CDS             5749..7122
                     /gene="cpxA"
                     /locus_tag="OPV72_003106"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress sensor histidine kinase CpxA"
                     /protein_id="HCR9915331.1"
                     /translation="MIGSLTARIFAIFWLTLALVLMLVLMLPKLDSRQMTELLDSEQR
                     QGLMIEQHVEAELANDPPNDLMWWRRLFRAIDKWAPPGQRLLLVTSEGRVIGAERSEM
                     QIIRNFIGQADNADHPQKKKYGRVEMVGPFSVRDGEDNYQLYLIRPASSSQSDFINLL
                     FDRPLLLLIVTMLVSSPLLLWLAWSLAKPARKLKNAADEVAQGNLRQHPELEAGPQEF
                     LAAGASFNQMVTALERMMTSQQRLLSDISHELRTPLTRLQLGTALLRRRGGESKELER
                     IETEAQRLDSMINDLLVMSRNQQKNALVSETMKANQLWGEVLDNAAFEAEQMGKSLTV
                     NYPPGPWPLYGNPNALESALENIVRNALRYSHTKIEVGFSVDKDGITITVDDDGPGVS
                     PEDREQIFRPFYRTDEARDRESGGTGLGLAIVESAMQQHRGWVKADDSPLGGLRLTLW
                     LPLYKRT"
     gene            complement(7173..7568)
                     /locus_tag="OPV72_003107"
     CDS             complement(7173..7568)
                     /locus_tag="OPV72_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HCR9915332.1"
                     /translation="MTEAENAVAIVKEFLVASMIPDAERAATYMHPEVKITFTGGRAM
                     AGAADIAQFNGARYKWVKKALGKFDAVQHDDYVVIYSNGTLYGEWPDGRPFADNRFID
                     RFEVRDGKITRMDVWNDSAEWILAPDISR"
     gene            complement(7580..8269)
                     /gene="yiiM"
                     /locus_tag="OPV72_003108"
     CDS             complement(7580..8269)
                     /gene="yiiM"
                     /locus_tag="OPV72_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-N-hydroxylaminopurine resistance protein"
                     /protein_id="HCR9915333.1"
                     /translation="MHYPVDVFIGKIRDYDGSRPSAIAKVQIDGELMLTELGLAGDQQ
                     AEKKIHGGPDRALCHYPREHYADWIRQFPEQATLFCAPAFGENLSTDGMTEHNVFIGD
                     IYRWGEALIQVTQPRSPCFKLNFHFAISDMALLMQNSGKTGWLYRVIAPGKVSSDAPL
                     ELASRLSDVSVHEAGVIAWSMPFDDEQYHRLLSAAGLSASWSRTMQKRRLSGKIEDSA
                     RRLWGDKTPPK"
     gene            complement(8339..8959)
                     /gene="sodA"
                     /locus_tag="OPV72_003109"
     CDS             complement(8339..8959)
                     /gene="sodA"
                     /locus_tag="OPV72_003109"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010345169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase [Mn]"
                     /protein_id="HCR9915334.1"
                     /translation="MSYTLPSLPYAYDALEPHFDKQTMEIHHTKHHQTYVNNANAALE
                     NLPEFADLPVEELITKLDQVPADKKTVLRNNAGGHANHSLFWKGLKKGTTLQGDLKAA
                     IERDFGSVDNFKAEFEKAAATRFGSGWAWLVLKGDKLAVVSTANQDSPLMGEAISGAS
                     GFPILGLDVWEHAYYLKFQNRRPDYIKEFWNVVNWDEAAARFAAKK"
     gene            9288..10270
                     /locus_tag="OPV72_003110"
                     /pseudo
     CDS             9288..10270
                     /locus_tag="OPV72_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462935.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
     gene            10289..10804
                     /locus_tag="OPV72_003111"
     CDS             10289..10804
                     /locus_tag="OPV72_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HCR9915335.1"
                     /translation="MNTFRKGLDLLLGAICCLVLAIMVGIACWQVVSRYILGVPSTLT
                     EEMLRFLLVWVSMLGMAFVAGQKQHISLTILLDKVSPTIRGWWDIILQVIFIAFSIWV
                     LIIGGLKISAISMLQISPALGIPMGKIYYALPCAGILIILYGLLNIVDALKAIHSATD
                     TTEHTLEKSHD"
     gene            10797..12104
                     /locus_tag="OPV72_003112"
     CDS             10797..12104
                     /locus_tag="OPV72_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HCR9915336.1"
                     /translation="MIDPIFASCTLIAVFVVLLAMGAPIGICIVIASFSTMMLVLPFD
                     ISMFATAQKMFSSLDSFALLAVPFFVLSGVIMNSGGIAARLVNFAKLFTGKLPGSLSY
                     TNIVGNMMFGAISGSAIAASTSIGGVMVPMSAREGYDRGFAAAVNIASAPTGMLIPPT
                     TAFILYALASGGTSIAALFAGGLVAGVLWGVGCMLVTLVVAKRRNYRVFFTVQKGMAL
                     KVAVEAIPSLLLIVIIVGGIVQGIFTAIEASAIAVVYTLLLTIVFYRTLKIKDLPSIL
                     LQTVVMTGVIMFLLATSSAMSFSMSITNIPAALSDMILGISANKLVILLVITVFLLII
                     GAFMDIGPAILIFTPILLPIMTKLGVDPVHFGIIMIYNLAIGTITPPVGSGLYVGASV
                     GKVKVEDVIKPLMPFYGAIIGVLLLITYIPEITLFLPRLLGIM"
     gene            complement(12260..12943)
                     /locus_tag="OPV72_003113"
     CDS             complement(12260..12943)
                     /locus_tag="OPV72_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462932.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligogalacturonate-specific porin KdgM family
                     protein"
                     /protein_id="HCR9915337.1"
                     /translation="MDSVMRKSLFLLLPLVVTNAHAVYVDVRHEYLDDSKANYDRAYI
                     SHRFANGVGFAIEAISKSGGDDTNKAFNDLETQGNEYTISYQFKTGDVAWQPGFVLET
                     GNGYSTYKPYFRATWTLNESWWVGARYRFEYVRRSSDIRDDDTINRMDVWAGYKWNNF
                     DWTIEGIYKKADKYDLYDGGKDNYEYNFRTAYIIDQWSPFVEVGNVSVNSNSDERQTR
                     FRVGIGYTF"
BASE COUNT         3117 a         3447 c         3280 g         3172 t
ORIGIN      
        1 ctatggaggc tatgaagaga gtgtaacgaa ccaccaaaag atataaaggt atacctttat
       61 atcttttggt tggtttcaca tatttttata gacacgatct taccccagtt ttaaaccggg
      121 ataagaatca ataagataat gagcaggggg gtgtaacgaa aatcagcggg aagacaaaat
      181 ggcgcaacta tggtcctgaa tctcttccgc cgatgcgcga ttaagcgtca gcaggttacg
      241 ctcggtcgcc agcagaacaa aagagtcgtc gctttggcgt accaccgcca gcgcatagcg
      301 tcccatatga tcgcgcgctt ccggcacctc ttccgccagc atcataaacg gactacgctg
      361 cgccagttcg ctctcggtta cccggcgcgc caggtattca tgccccatca gatcgcccgg
      421 cagcggaagc cagcgagtgc tgatgcgcgt gagatcgtta tccagttgtt cccgaacgtc
      481 aggacggatg caagaaatat ggatatgcaa atggtcctgt gaacgaccaa gccgcgaatt
      541 aatcgccagc gagaccgcgc tatccggaat atcatgcccg tattttttac tcatatagcc
      601 gcgagcctgc caggccagcc agaaaaagtt gggcgtagcg ggttccagca atagcgggct
      661 ttctgtaccg ttgatacggt aggtgggcat caataaatat tgcaacggac cgtgacgatc
      721 tttaaagatg acatagccgg cgcgaggttt gacttccgcg caaggcgctg ggttttgatg
      781 ctgtaactga tcgggcaggc accgttcaag cacgatttcc cgtaatgcat caggattgcc
      841 ggaaaatttc cagtaaccga cgcccgccgc ggcgacaatc actatcaccg ccagtaaaaa
      901 gtagcctgtt tttttcatga tatgcgttcc ctgtgaccca tagacgggga agagtaacgc
      961 aaaattgtgg caaagaaaaa acccggtaac ataatacgtt accgggttta taaacggttt
     1021 agcgtttgct gatttggtcg aacgtaccgc cattagcaaa gtgatctttt tgcgccttca
     1081 cccagccgcc aaacacctcg tcaatggtga atagcttcag cttcggaaac gcatcgtcgt
     1141 attttttcgc cacgtcagca tcgcgcggac ggtagaagtt tttcgctgct atctcctgcc
     1201 cttccggcga atagagatac ttgagatacg cctccgccac cgcattcgtc cctttcttct
     1261 caacgacttt atccaccacg gacacggtcg gctctgcgag gatagattca ctcggggtca
     1321 ctatctcgaa tttatcttta cccagttcgt tcgtcgccag cagcgcttcg ttttcccagg
     1381 cgatcagcac atcaccgata ccgcgttcaa cgaaagtatt ggttgagcca cgcgcaccgg
     1441 agtccagcac ttcaacgttt ttaaacaggg ctttgacaaa gtcctgggct ttggcctgat
     1501 cgttattgtt gtggtgcagg gcgtagcccc atgccgccag atagttccag cgtgcgccgc
     1561 cggagctttt cgggtttggc gtaatcaccg acacaccggg tttaatcaga tcgttccagt
     1621 catgaatttg ttttggattg cctttgcgga ccaggaaaac aatggtggag gtgtaaggtg
     1681 ctgagttatc cggcagacgc ttgatccagt ttttatcgat acgaccacgt tcagcaatag
     1741 cgtccacatc gtaagccagc gccagcgtca cgacatcggc ttcaatgccg ttaatgacgg
     1801 aagtcgcctg tttacctgaa ccgccgtgcg actggcggat cacgacgttg tcgccggttt
     1861 cctgcttcca gtgcgcgcta aacgctttgt tgtactgctc gtacagctca cgcgttggat
     1921 cgtacgatac gttaagtaac tgaatatcct ttgccagaat gctggttgac gccagcaata
     1981 atgtgaaccc cacgccccac tttttcatcg cccgactcgc ttatgttgtg ttgtgatgag
     2041 caaagcgtgc cagaaagaga tccaaacatt aaagaataaa aaaagattgg ctataacttc
     2101 gaggaataaa tctgagggat tgccggatgg cggctagcgc ctaatccggc ctacacgttt
     2161 ctgcaacctg taggcctgat aagcgtagcg ccatcaggcg cgcaaaaaca atcagtacag
     2221 ttttttcgcg cactccatcc agtcgctttt gaacggacgc ttcatgtttt caatcgcatc
     2281 gatgatgtca tgatgaacaa gctgctcgtt ctggataccg acacaacgac cgccatggcc
     2341 ttccagcagc aggtcaatag catacgcgcc catacgggaa gccagaatgc gatcgtaagg
     2401 taccggggaa ccaccgcgct gaatgtggcc gagcaccgtc gcacgcgttt cacggcccgt
     2461 ttctttttca ataaagtgcg ccagttcgtc aacatcgcac atatgctcag taatagcgac
     2521 gatagcgtgt tttttccctt tcgcgatccc ggctttgatt tcggccacca gatcttcgcg
     2581 attaaattca acttccggca ccacgataaa ctcacagccg ccagcaatag ccgccgccaa
     2641 cgtcaggtcg ccgcaataac ggcccatcac ctcaacgata gagatacgct ggtgagaaga
     2701 ggaggtgtca cgcagacggt caatcgcttc cactacagtg ccgagagcag tgaagtagcc
     2761 gatagtgtag tcggtgcctt tgatgtcgtt atcgatagtg cctggcagac cgatgcacgg
     2821 gaagcccatt tcagtcagac gttttgcacc catataagaa ccgtcgccgc caataactac
     2881 cagcgcatcg ataccgcgtt ttttcaggtt ttcgatcgcg acagcgcgaa tattttcgtc
     2941 acggaattcc gggaaacggg cggaaccgag gaaagtaccg ccacggttga tcatgtcaga
     3001 tacgctgtaa cggtcaagct gaaccatacg atcttcatac aggcccagat agccgtcata
     3061 aatgcccatg acttccagcc cttccgtcaa cgctgcgcgc acaacaccgc ggattgccgc
     3121 gttcatgccc ggcgcatcac cgccgcttgt caacacaccg attttcttaa tcatgactac
     3181 ctctgaactt tggaatgcaa aatgaaatct attgccggaa gccgatttcg cacttcgaaa
     3241 cgatccaacg aatatacaga tagtataaca atcccttcct gctgaattga ttcaggtcag
     3301 gccaaatggc ggtaatttat acacaaaatg ctggcctggc tcacttttta acaatcaatt
     3361 atacaagctc gaacttcctg ccttccctgg ggacgactga acagggatcc tgatgaataa
     3421 tgacatctga acccggaaaa cgccgcaaaa tcgcctgctc tacctggtca gccacaaaat
     3481 gcgcctgaac gagcggcaga ttatcttcca tttccaaatg aatctgaata aagcgagtcg
     3541 gccctgactg ccgcgtgcgg agatcgtgcg cgccgctgac tcccggccat gacgtcacga
     3601 tatcaataat ttcctgtcgt tccgcatcgg gcagcgcgcg atccaataat gactgcaccg
     3661 cctcataccc catacgtaac gcgctataca aaatatagat gccgatacct aacgcaaaca
     3721 gggcatccgc acgatgccaa ccgtaccagg ataaccccag cgcgataaga atcgctccgt
     3781 tcatcataac atcagactga taatgaagca tatccgcccg taccgcctga ctttgggtct
     3841 tgcgtaccac ccagcgctga aacgtgacca gtataatagt gcatatcaga gcgatgacgg
     3901 taacgccaat ccccacgccg gggtcgttca ttggcgtcgg cttaatcaga ttctggatac
     3961 tggtcaaaaa caacgccgaa ccggaaataa acatactttg cgccagcgcc gccagcgact
     4021 ccgctttacc gtgaccaaac gtatgttcat catctgcggg ttgcagcgaa taacgcacga
     4081 ccaacaaatt cgtcaatgac gcggcaatat ccaccagcga gtccaccaac gccgccagaa
     4141 tactcaccga tcccgtatac caccacgcaa aaattttgat caaaagtaac gctgatgcca
     4201 tcgccgttgc cgcgatagcc gcccggctaa ccagccgtcc ataggtttga ttcataaata
     4261 ctcccgctat cttctgccgg tagtataacg gatggtttaa aacagtaagc taataacaga
     4321 atgacaaact ggagataaaa aaaaccccca catcatgtgg gggaagacag ggatggtgtc
     4381 tatggcaagg aaaacagggt tgttactggg aacgtgagtt gctactactc aataatttca
     4441 acgatgaact tttttgccat tgcgccacgt cgcgcagttg ctccattcgt tgctgatgct
     4501 tttcattcaa aaccgcttgc tgctccggcg ttaacaggcg atacatctgg ttacgcacgc
     4561 gggccatttc gacctggcgg gcaacctgct cttgcgccat tttttctgcc tgagcgcgca
     4621 caacgctttc atcaaatttt tctgcggtga caagccgatg cattgtctcc atttcgctaa
     4681 cattaacagg aggctgttcg tgccttgcct gctgcataag atctcgcatc tgctgacgct
     4741 gatgttcggt taaacttatg ccgtcaaaca tatgattttg cgcgctacgc tgcgtggccc
     4801 cgtcaccggg gtgccagtta tcgcttgtaa caacttcagc tgcgtggctt aaaaaactga
     4861 atgccagcgt tgaggccata acagcagcgg taactttgcg catcgcttgc tcccaaaatc
     4921 ttttctgtcg cgattcaacg agagacagtt tacgattcgg gctgcaaaca tgcgtcaggg
     4981 ggtgtaaaac aacgtaaagt catggattag cgacgcctga tgacgtaatt tctgcctcgg
     5041 aggtacgtaa acaatgaata aaatcctgtt agttgatgat gaccgagagc tgacttccct
     5101 gttaaaagag ctcctcgaaa tggaaggttt taatgtcctg gtggcccacg acggcgagca
     5161 ggcgcttgag cttttggatg acagcatcga tttacttttg cttgacgtca tgatgccgaa
     5221 gaaaaacggt atcgatacgt tgaaagcgct tcgccagaca caccagacgc ctgtcattat
     5281 gctgaccgcg cgcggcaacg agctggatcg cgttctcggc cttgagctgg gcgcggacga
     5341 ctatttgccc aaaccgttta acgaccgcga gctggtagcg cgcatcaggg ctattttgcg
     5401 ccgttcccac tggagcgagc agcagcagag cagcgacaac ggctcgccga cgctggaagt
     5461 tgatgcgcta agccttaatc cgggtcgcca ggaagccagt ttcgatggcc aaacgctgga
     5521 gctgaccggt acggaattca ccctgctcta tttactggcg caacacctcg gccaggtggt
     5581 ttcccgtgaa catttaagtc aggaagtgct gggtaagcgc ctgacgccgt tcgatcgcgc
     5641 cattgatatg catatttcta acctgcgccg caaactgccg gaacgcaaag acggtcaccc
     5701 gtggtttaaa acattgcgtg gtcgcggcta tctgatggtt tccgcttcat gataggaagt
     5761 ttaaccgcgc gcatcttcgc catcttctgg ttgacgctgg cgctggtgct aatgctggta
     5821 ctgatgttgc ccaagctcga ttcacgccag atgaccgagc tgctggacag cgaacagcgc
     5881 cagggattga tgatagagca acatgtagaa gctgaacttg cgaacgatcc gcccaacgac
     5941 ctgatgtggt ggcgtcgcct gttccgcgcg atcgataagt gggcgccgcc tggacagcgg
     6001 ttattactgg tgacctctga aggacgcgtg atcggtgctg aacgcagcga aatgcagatc
     6061 attcgtaact tcattggtca ggcggataac gccgatcatc cgcagaagaa aaaatatggc
     6121 cgcgtagaga tggtggggcc gttctccgtt cgcgacggag aggataatta ccagctttac
     6181 ctgattcgac cggccagcag ttcgcaatcc gattttatta atctgctgtt tgaccgcccg
     6241 cttctgttgc tcattgtcac gatgctggtc agttcgccgc tcttgctatg gctggcatgg
     6301 agtctggcga aaccggcgcg taagttgaaa aacgcggctg atgaagtggc gcaaggcaac
     6361 ctgcgtcagc atccggagct ggaggcgggt ccgcaggagt tcctcgccgc tggcgccagt
     6421 tttaaccaga tggtgacggc gctggaacgg atgatgacct cgcagcagcg tttgctgtca
     6481 gacatctccc atgagctgcg aacgcccctt acgcgcctgc aactgggtac cgcgctgctg
     6541 cgtcgtcgtg gcggcgaaag caaagagctg gagcgtattg aaaccgaagc gcagcgtctg
     6601 gacagcatga tcaatgacct gctggtgatg tcgcgtaacc aacagaaaaa tgcgctggtc
     6661 agcgaaacga tgaaagccaa tcagctatgg ggcgaagtgc tggataacgc cgcctttgaa
     6721 gccgaacaga tgggcaagtc gttaacggta aattatccgc cggggccgtg gccgctctat
     6781 ggcaacccaa acgcactgga aagcgcgctg gaaaatattg ttcgtaatgc gctgcgctat
     6841 tcacatacga agattgaagt cggcttctcg gtggataaag acggtattac gatcacggtc
     6901 gatgacgacg gaccgggcgt aagccctgaa gaccgcgagc agatcttccg tccgttctat
     6961 cgcactgatg aggcgcgcga ccgcgagtct ggcggcaccg ggctggggct ggcgattgtc
     7021 gaaagcgcca tgcagcagca ccgcggctgg gtgaaggctg acgatagccc gctgggtggg
     7081 ttgcggctca cgctgtggct accgctgtac aagcgaacct aaaaaccatc ggcctgcgaa
     7141 tgcaggccga ttttttatct cgccgtcgag atttaccggg aaatgtctgg cgctaaaatc
     7201 cactcggcgc tgtcgttcca cacgtccatc cgggtaattt tgccatcgcg cacttcgaaa
     7261 cgatcgataa agcggttatc ggcaaacggg cgaccgtcgg gccattcgcc atacaacgta
     7321 ccgttggaat aaatcacaac gtaatcatca tgctgcaccg catcaaactt gcccagcgcc
     7381 ttcttcaccc acttgtagcg agcgccgtta aactgcgcga tatctgccgc gcccgccatc
     7441 gcccggcctc cggtgaaggt aattttcacc tccgggtgca tatacgttgc ggcgcgttca
     7501 gcatcgggaa tcatcgaggc caccaaaaat tcttttacga tcgccaccgc attttcagct
     7561 tcagtcataa tccttccttt cattttggcg gagttttatc cccccacagt cgtctggcgc
     7621 tatcttcaat tttgccgctc aaacgacgct tctgcatggt gcggctccag ctcgccgaca
     7681 gcccggcggc gctcagcagc cggtgatatt gttcgtcatc aaacggcata gaccaggcga
     7741 taacacccgc ttcatgaacc gagacatcgc tcagacgcga cgccagttcc agcggcgcat
     7801 cgctggagac cttacctggc gcaatgaccc gatacaacca gccagttttt ccgctgttct
     7861 gcataaggag ggccatgtcg ctgatggcaa agtggaaatt aagtttaaag catggagagc
     7921 gcggctgagt gacctggatc aacgcctcgc cccagcggta gatgtcgcca ataaacacgt
     7981 tgtgttcggt cattccgtcc gtcgacagat tctcgccaaa cgccggggcg caaaacagcg
     8041 tcgcctgctc ggggaactgg cgaatccaat cagcatagtg ttcgcggggg taatgacata
     8101 gcgcgcggtc ggggccgccg tggattttct tttcggcctg ctgatcgcct gccagaccca
     8161 gctcggtcag catgagttcg ccgtcgattt gcaccttggc gatagcgctc gggcggctgc
     8221 cgtcatagtc acgaattttg ccaataaaca cgtcaaccgg ataatgcatc tgctgctcct
     8281 tacgcggata caaaaaaagc gagtcatcag actcgcttct acagacgtgc aatgcaaatt
     8341 attttttagc ggcgaaacgc gctgctgctt cgtcccagtt caccacgttc cagaactctt
     8401 tgatgtagtc cgggcggcgg ttctggaatt tcagatagta agcgtgttcc cacacgtcca
     8461 gacccaggat cgggaagccg gaagcgccgg aaatggcttc acccatcagc ggggaatcct
     8521 ggtttgcggt agaaaccaca gccagtttgt cgcctttcag caccagccac gcccagccgg
     8581 agccgaaacg ggttgctgct gctttttcga attcagcttt gaagttgtca acggaaccga
     8641 agtcacgctc gatagccgct ttcagatcgc cctgcagagt ggtgcctttt ttcagccctt
     8701 tccagaacag gctgtggtta gcgtggccgc ccgcgttgtt acgcagcacg gtttttttgt
     8761 ccgctggcac ctggtccagt ttagtaatca gttcttcaac cggcaggtca gcaaactcag
     8821 gcagattttc cagcgccgcg ttagcgttgt tgacataggt ttgatggtgt ttggtgtggt
     8881 gaatctccat cgtctgctta tcgaagtgcg gttccagtgc atcataagcg tacggcaggg
     8941 atggcagtgt ataactcata atcatctcca ttattgtcga gcggcacagt gttaacgccg
     9001 cgtaagcagt tggttcatta tagttaatta aatgatattg aaaatgatta tcaatgccgt
     9061 actttttcca gggttataaa cgttacggca tccgctgaaa aaaaccgatt tttacgcctc
     9121 caaccgaaac cgcctgttga tgaattcctg gaaatcatga aatgtgaaac agggtttcaa
     9181 aatctttctt ttggtgccaa tttttatcag cggtggcaaa atcaagaagg ttataatttc
     9241 accatgcaat tacattcccg gtaaattatt acaattgcga gggaattatg aagcaacctg
     9301 gttttatacg tctggctacg ttggccttac tctccacact ctctttcttc tcccacggcg
     9361 aaaccatttt gcgcctggcc tacgctgaaa atagccagcc ggtaaaagat gcgttgcact
     9421 tcctggggca gcaagttgaa gagaaaacgg gcggcgatat caaagtacag tacttcccgg
     9481 acggacagct tggcggcgag cgcgaactgg tggagttgac gcaggtcggc gtcgtcgaca
     9541 tcactaaagt gtcgtccggg ctgatggaga gtttttcgcc tgagtacggc gtgttctcac
     9601 ttccctacct gtttgccacc gtcgatgaat actaccgcgt aatggataac ccacaggtga
     9661 ggagcctgtt tatcagtcca ccgccgcaca gggttttgtc ggcgtaggct ggtatgattc
     9721 cggcgcgcgt aatttttata tgagcaaagc gccggttaaa cgcattgagg atttacgcgg
     9781 gaagaagatc cgcgtcatgc agagtgagac ggcgatccaa actctcaaac tgctgggcgc
     9841 ttcgcccatc gccatgagcc aggcggaggt ctatacctcg ttacaacaag gcattctcga
     9901 cggcgcggaa aacaatgagt tcgctctcac catcgcccgc cacggcgaag tcgcccgtta
     9961 ttacacctac gatatgcaca cccgcattcc cgatatcctg ctaatgagta ccctcacgct
    10021 ggaaaagctg acgccggaac agcagcgcat cgtcgaagcc gccatcaagg cgtcgatcga
    10081 atttgagaaa gccgcatggg acaaggaaat agagaaaacc aggctggcgg cggtaaaaga
    10141 tttcaacgtt gaattctacg agatcgacaa aaaacccttc cagaaggcag tacagcctat
    10201 ttacgacggt ctgaaaaaca aaccgcggct ttacgggctg tatcaacgta tccagacagc
    10261 aaaaaattaa tctaatcagg aaattaagat gaacacattc agaaaaggac ttgatttatt
    10321 gctgggcgct atctgttgcc tggtgctggc gataatggtt ggcatcgcct gctggcaggt
    10381 ggtgagccgc tacattctgg gcgttcccag cacccttacc gaagagatgc tgcgatttct
    10441 cctggtgtgg gtatcaatgc tgggcatggc ttttgtcgcc ggtcagaaac agcatatcag
    10501 tctgactatc ttactggata aggtgtcgcc gacgattcgc ggctggtggg atatcatcct
    10561 gcaggtcatt tttatcgcgt tttccatttg ggtattgatt atcggcggct taaagatttc
    10621 tgcgatttct atgctgcaaa tctcccctgc gctgggcatt ccgatgggga aaatttatta
    10681 cgcgctcccc tgcgcgggca tactgatcat cctctatggg ctactgaata tcgttgacgc
    10741 cctgaaagct atccattccg ccacggatac cactgagcac actctggaga aatcacatga
    10801 ttgaccctat ttttgcgtcc tgtacgctaa ttgccgtctt tgttgtttta ctggccatgg
    10861 gcgcgcctat cgggatctgc atcgttatcg cctctttcag caccatgatg ctggtactgc
    10921 ctttcgatat ttcgatgttc gccaccgcgc aaaaaatgtt ctccagcctg gacagttttg
    10981 ccttgctggc cgtgccgttc ttcgttttgt ccggggtgat catgaatagc gggggaattg
    11041 ccgcccgact ggtcaatttt gccaaactgt ttactggcaa actgcccggc tcgctctctt
    11101 acaccaacat cgtcggcaat atgatgttcg gtgcaatttc cggatcggcg attgccgcct
    11161 caacctctat cggcggcgtg atggtgccga tgagcgcgcg cgaaggttac gatcgcggtt
    11221 ttgcggccgc ggtgaatatc gcctccgcgc cgacgggaat gttaattccg cccaccacgg
    11281 cttttatcct ttatgcgctg gcaagcgggg gaacatcgat tgccgctctg ttcgccggcg
    11341 gtctggtcgc gggagtgctg tggggcgttg gctgtatgct ggtcacgctg gtggtcgcta
    11401 agcgtcgaaa ttatcgggtt ttcttcaccg tccaaaaagg catggcgcta aaagttgccg
    11461 ttgaggccat tcccagcctg ttactgatcg tgattattgt cggcggcatt gtgcagggga
    11521 ttttcaccgc cattgaagcc tccgcgattg ccgtggtgta tacgttattg ctgacgatag
    11581 tgttttaccg cacgctgaaa attaaggatt tgccttcgat tttgctccag acagtggtaa
    11641 tgaccggggt catcatgttc ctgctggcaa cctcttcggc gatgtccttc tcgatgtcga
    11701 tcaccaatat tcctgcggcg ctgagcgata tgatcctcgg tatttccgcc aataaactgg
    11761 ttatcctgtt agtcattacc gtctttttgt tgattatcgg cgcatttatg gatatcggtc
    11821 cggccattct gatttttacc ccgattctgc tgccgattat gactaaactg ggcgtcgatc
    11881 cggtgcattt cggcattatc atgatctata acctggcgat aggcaccatt acgccgccag
    11941 ttggcagtgg tttatatgtc ggggcgagcg tcggtaaggt caaagttgag gacgttatca
    12001 aaccgttgat gcctttttac ggcgcgatta tcggcgttct gttattaatt acctacattc
    12061 cggaaatcac actgttttta ccccgtctac tgggcatcat gtaaggcata gtttcctgca
    12121 catctcgttg ccggatggcg attcgcgtct tatccggcca acgcgcgata ataattatcc
    12181 gcaggtcatc accaggtaaa aaaaccggct acctataaag tagccggaaa agggaataaa
    12241 taataaacag ggataatgat tagaatgtgt agcctatacc cacgcggaaa cgggtttgtc
    12301 tttcatcgct gttgctattg acggaaacat tacctacctc aacgaatggc gaccattggt
    12361 caataatata ggcagttctg aagttatatt catagttatc tttgccgcca tcgtaaagat
    12421 catatttatc ggctttctta taaattcctt cgattgtcca gtcaaagttg ttccatttat
    12481 aacccgccca gacatccata cgattgatgg tatcatcatc acggatatca gaagaacggc
    12541 gtacatattc aaaacgatag cgcgcgccaa cccaccaact ttcatttaat gtccacgtcg
    12601 cgcggaagta aggcttatag gtagagtaac cgttgcctgt ttccagcaca aaacccggtt
    12661 gccaggcgac atcaccggtt ttaaattggt agcttatcgt atattcgtta ccctgtgttt
    12721 ccaggtcatt aaacgcttta ttggtgtcat ccccgcctga ttttgagata gcttctatcg
    12781 caaaaccaac accattcgca aaccgatgag aaatatacgc acggtcatag ttagctttac
    12841 tgtcatcaag atattcatga cgaacatcga catatactgc atgcgcattt gttacaacaa
    12901 gaggtaatag taagaaaaga gattttctca taacagaatc catttaattt aaaattaaaa
    12961 cgttgtttca tgtcagaccg ttacaaccat aatacgcaat gtgaatggcg acaata
//
LOCUS       DAJVBX010000132        12974 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.132, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000132 DAJVBX010000000
VERSION     DAJVBX010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 12974)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12974)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12974
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.132"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..270
                     /locus_tag="OPV72_003114"
     CDS             <1..270
                     /locus_tag="OPV72_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4427 domain-containing protein"
                     /protein_id="HCR9915338.1"
                     /translation="VRALLQAGMIKVNKEGRYLLDVNLASVDWPLRRKEAFASHVAGW
                     LKHRFDIEAGRYSVRGKDDYDAIPSYETPLKDQHPFYNHTVNVDW"
     gene            complement(429..1520)
                     /gene="ychF"
                     /locus_tag="OPV72_003115"
     CDS             complement(429..1520)
                     /gene="ychF"
                     /locus_tag="OPV72_003115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001538644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HCR9915339.1"
                     /translation="MGFKCGIVGLPNVGKSTLFNALTKAGIEAANFPFCTIEPNTGVV
                     PMPDPRLDQLAEIVKPQRILPTTMEFVDIAGLVKGASKGEGLGNQFLTNIRETEAIGH
                     VVRCFENDNIIHVAGKVNPAEDIDVINTELALADLDTCERAIHRVQKKAKGGDKDAKA
                     ELAALEKCLPHLAEAGMLRSLDLTDEDKAAIRYLSFLTLKPTMYIANVNEDGFENNPY
                     LDQVREIAAKEGSVVVPVCAAVEADIAELDDDERDEFMAELGLEEPGLNRVIRAGYRL
                     LNLQTYFTAGVKEVRAWTIPVGATAPQAAGKIHTDFEKGFIRAQTIAFDDFITYKGEQ
                     GAKEAGKMRAEGKDYIVKDGDIMNFLFNV"
     gene            complement(1637..2221)
                     /gene="pth"
                     /locus_tag="OPV72_003116"
     CDS             complement(1637..2221)
                     /gene="pth"
                     /locus_tag="OPV72_003116"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002910438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HCR9915340.1"
                     /translation="MAIKLIVGLANPGAEYAATRHNAGAWYVDLLAERLRAPLREEPK
                     FFGYTSRITLEGEDVRLLVPTTFMNLSGKAVGAMASFYRIQPDEILVAHDELDLPPGV
                     AKFKLGGGHGGHNGLKDIISKLGNNPNFHRLRVGIGHPGDKNKVVGFVLGKPPVSEQK
                     LIDEAIDEAARCTELWFKEGLAKATSRLHTFKAQ"
     gene            2497..2718
                     /gene="ychH"
                     /locus_tag="OPV72_003117"
     CDS             2497..2718
                     /gene="ychH"
                     /locus_tag="OPV72_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress-induced protein YchH"
                     /protein_id="HCR9915341.1"
                     /translation="MKRKNASLFGNVLMGLGLVVMVVGVGYSILNQLPQFNLPQFFAH
                     GAILSIFVGAVLWLAGARVGGHEQVSDKY"
     gene            complement(2820..4505)
                     /gene="dauA"
                     /locus_tag="OPV72_003118"
     CDS             complement(2820..4505)
                     /gene="dauA"
                     /locus_tag="OPV72_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001525165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C4-dicarboxylic acid transporter DauA"
                     /protein_id="HCR9915342.1"
                     /translation="MNKLFSSHVMPFRALIDACWKEKYTASRFTRDVIAGITVGIIAI
                     PLAMALAIGSGVAPQYGLYTSAVAGIVIALTGGSRFSVSGPTAAFVVILYPVSQQFGL
                     AGLLVATLMSGFFLILFGLARLGRLIEYIPVSVTLGFTSGIGITIGTMQIKDFLGLQM
                     AHVPEHYLQKVGALFMALPTVNIGDAAIGVVTLGTLIFWPRLGIRLPGHLPALLAGCA
                     VMGIVNLLGGNVATIGSQFHYVLADGTQGNGIPQLLPQLMLPWSLPGSDFTLSWDSLR
                     ALLPAAFSMAMLGAIESLLCAVVLDGMTGTKHKANSELIGQGLGNMVAPFFGGITATA
                     AIARSAANVRAGATSPVSAVIHAILVILALLVLAPLLSWLPLSAMAALLLMVAWNMSE
                     AHKVVDLLRHAPKDDIIVMLLCMSLTVLFDMVIAISVGIVLASLLFMRRIARMTRLAP
                     VNVDVPEDVLVLRVIGPLFFAAAEGLFTDLESRIKGKRIVVLKWDAVPVLDAGGLDAF
                     QRFVKRLPEGCELRISNLEFQPLRTMARAGIKPIPGRLTFFPNRTEALADLLS"
     gene            complement(4630..5577)
                     /gene="prs"
                     /locus_tag="OPV72_003119"
     CDS             complement(4630..5577)
                     /gene="prs"
                     /locus_tag="OPV72_003119"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002910407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HCR9915343.1"
                     /translation="MPDMKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQI
                     NENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRASAGRITAVIPYFGYARQDRRVR
                     SARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLEDMLQLN
                     LDNPIVVSPDIGGVVRARAIAKLLNDTDMAIIDKRRPRANVSQVMHIIGDVAGRDCVL
                     VDDMIDTGGTLCKAAEALKERGAKRVFAYATHPIFSGNAANNLRNSVIDEVVVCDTIP
                     LTDEIKALPNVRTLTLSGMLAEAIRRISNEESISAMFEH"
     gene            complement(5843..6694)
                     /gene="ispE"
                     /locus_tag="OPV72_003120"
     CDS             complement(5843..6694)
                     /gene="ispE"
                     /locus_tag="OPV72_003120"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HCR9915344.1"
                     /translation="MMTHWPSPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDTLHIE
                     PRHDGEIHLLTPVTGVENEDNLIVRAARLLMKVASESGRLPAGSGADISIEKRLPMGG
                     GLGGGSSNAATVLVALNHLWQCGLSIDELATLGLTLGADVPVFVRGHAAFAEGVGEIL
                     TPVNPPEKWYLVAHPGVSIPTPVIFKDPQLPRNTPKRSIDTLLKCEFSNDCEVIARKR
                     FREVDAALSWLLEYAPSRLTGTGACVFAEFDTESCARQVLEQAPEWLNAFVAKGVNLS
                     PLHRELL"
     gene            complement(6691..7314)
                     /gene="lolB"
                     /locus_tag="OPV72_003121"
     CDS             complement(6691..7314)
                     /gene="lolB"
                     /locus_tag="OPV72_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein localization protein LolB"
                     /protein_id="HCR9915345.1"
                     /translation="MTLPDFRLIRLLPLASLVLTACTLPGHKGPGKSPDSPQWRQHQQ
                     EVRHLNQYQTRGAFAYISDDQKVYARFFWQQTGQDRYRLLLTNPLGSTELELNAQPGN
                     VQLVDNKGQRYTADDAEEMIGKLTGMPIPLNSLRQWILGLPGDATDYKLDDQYRLSEV
                     NYHQDGKNWKVVYGGYDSKTQPAMPANMELSDGSQRIKLKMDNWIVK"
     gene            7628..8884
                     /gene="hemA"
                     /locus_tag="OPV72_003122"
     CDS             7628..8884
                     /gene="hemA"
                     /locus_tag="OPV72_003122"
                     /EC_number="1.2.1.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_041689438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl-tRNA reductase"
                     /protein_id="HCR9915346.1"
                     /translation="MTLLALGINHKTAPVSLRERVTFSPDTLDQALDSLLAQPMVQGG
                     VVLSTCNRTELYLSVEEQDNLQEALIRWLCDYHNLNEDDLRNSLYWHQDNDAVSHLMR
                     VASGLDSLVLGEPQILGQVKKAFADSQKGHLNASALERMFQKSFSVAKRVRTETDIGA
                     SAVSVAFAACTLARQIFESLSTVTVLLVGAGETIELVARHLREHKVQKMIIANRTRER
                     AQALADEVGAEVISLSDIDARLQDADIIISSTASPLPIIGKGMVERALKSRRNQPMLL
                     VDIAVPRDVEPEVGKLANAYLYSVDDLQSIISHNLAQRQAAAVEAETIVEQEASEFMA
                     WLRAQGASETIREYRSQSEQIRDELTTKALSALQQGGDAQAILQDLAWKLTNRLIHAP
                     TKSLQQAARDGDDERLNILRDSLGLE"
     gene            8925..10007
                     /gene="prfA"
                     /locus_tag="OPV72_003123"
     CDS             8925..10007
                     /gene="prfA"
                     /locus_tag="OPV72_003123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012132158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HCR9915347.1"
                     /translation="MKPSIVAKLEALHERHEEVQALLGDAGIIADQDRFRALSREYAQ
                     LSDVSRCFTDWQQVQDDIETAQMMLDDPEMREMAQEELREAKEKSEQLEQQLQVLLLP
                     KDPDDERNAFLEVRAGTGGDEAALFAGDLFRMYSRYAEARRWRVEIMSMSEGEHGGYK
                     EIIAKISGDGVYGRLKFESGGHRVQRVPATESQGRIHTSACTVAVMPELPEAELPDIN
                     PADLRIDTFRSSGAGGQHVNTTDSAIRITHLPTGIVVECQDERSQHKNKAKALSVLGA
                     RIHAAETAKRQQAEASTRRNLLGSGDRSDRNRTYNFPQGRVTDHRINLTLYRLDETME
                     GKLDMLIEPIVQEHQADLLAALSEQE"
     gene            10007..10840
                     /gene="prmC"
                     /locus_tag="OPV72_003124"
     CDS             10007..10840
                     /gene="prmC"
                     /locus_tag="OPV72_003124"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HCR9915348.1"
                     /translation="MDFQHWLHEAVNQLRDSDSPRRDAEILLEYVTGKRRTYIMAFGE
                     TPLTDVQQQQLAELLQRRKQGEPIAYLTGLREFWSLPLFVSPATLIPRPDTECLVEQA
                     LARLPVKTCRILDLGTGTGAIALALACERPDCEVTAVDRMPDAVALAIRNAEHLAIRN
                     VRILQSCWFSALSGQQFDMIVSNPPYIDAQDPHLSEGDVRFEPRSALVADENGMADLT
                     HIIDNARQMLTPGGFLLLEHGWRQGEAVRAAFRRSGYTDVETCRDYGGNERVACGRFT
                     P"
     gene            10837..11226
                     /locus_tag="OPV72_003125"
     CDS             10837..11226
                     /locus_tag="OPV72_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SirB family protein"
                     /protein_id="HCR9915349.1"
                     /translation="MTIAMLLTLHLICVALSVSLFVARYWWRYCGHALAAARWTRIVP
                     PVIDTLLLLSGIGLIVKTHILPFTESGSWLTEKLFGVIIYIVLGFIALDYRQARSQQA
                     RFIAFPLALVVLYIIIKLATTKIPLLG"
     gene            11230..12039
                     /locus_tag="OPV72_003126"
     CDS             11230..12039
                     /locus_tag="OPV72_003126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat-containing protein"
                     /protein_id="HCR9915350.1"
                     /translation="MRSLADFEFNNAPLCDGMILASEMIRLDFPTQFVYDELERLVSL
                     AQEEISQLLSQDEQLEKLLALFYGEWGFTDSRGVYRLSDALWLDKVLKKRQGSAVSLG
                     AILLWIANRLDLPLVPVIFPTQLILRIESLEGEMWLINPFNGETLDEHTLEVWLKGNI
                     SPVAELFNEDLDEADNAEVIRKLLDTLKSSLMEERQMELALRVSEALLQFNPEDPYEI
                     RDRGLIYAQLECEHVALTDLSYFVEQCPEDPISEMIRAQINTIAHKQIVLH"
     gene            12077..12931
                     /gene="kdsA"
                     /locus_tag="OPV72_003127"
     CDS             12077..12931
                     /gene="kdsA"
                     /locus_tag="OPV72_003127"
                     /EC_number="2.5.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-8-phosphooctulonate synthase"
                     /protein_id="HCR9915351.1"
                     /translation="MKQKVVNIGDIKVANDLPFVLFGGMNVLESRDLAMRICEHYVTV
                     TQKLGIPYVFKASFDKANRSSIHSYRGPGLEEGMKIFQELKQTFGVKVITDVHEASQA
                     QPVADVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQFVSPGQMGNIVDKFHEGGN
                     DKVILCDRGANFGYDNLVVDMLGFSVMKKVSGNSPVIFDVTHALQCRDPFGAASGGRR
                     GQVTELARAGMAVGLAGLFLESHPDPANAKCDGPSALPLAKLEQFLTQIKAIDDLVKS
                     FDELDTEN"
BASE COUNT         3070 a         3385 c         3568 g         2951 t
ORIGIN      
        1 gtacgggcgt tactgcaggc tggaatgatc aaggttaata aagaagggcg gtacttatta
       61 gatgttaatt tggcttctgt tgattggcca ttaagaagaa aagaggcttt cgcaagtcat
      121 gttgcgggat ggctcaaaca tcgttttgat atcgaagcgg gaaggtattc cgttcgggga
      181 aaagatgatt atgatgcgat cccaagttat gagacgccgc taaaggatca gcatcctttt
      241 tataatcata cagtgaatgt cgactggtaa ttaagaaaaa aacttaccct gttagctctg
      301 cgttaattga gcctgtcagt atgagttgag atattatgaa ataaaaaatc cacgcggctg
      361 cgtggatttt atgagtttct ttgcctctta tgagattcag caaaacctca taagacaaca
      421 atttttactt agacgttgaa caggaagttc attatatcgc catctttaac gatataatct
      481 ttgccttccg ctcgcatctt accggcttct ttcgcgcctt gttcaccttt ataggtaata
      541 aagtcgtcaa aggcgatagt ttgagcgcgg ataaagcctt tttcgaagtc ggtatggatt
      601 ttacctgctg cttgcggcgc ggttgcgcca accggaatgg tccatgcgcg aacttctttc
      661 accccggcgg tgaagtaggt ctggaggttc agcaggcgat aaccagcgcg aataacgcgg
      721 ttcagccccg gttcttccag acccagttca gccataaatt cgtcacgctc gtcatcatcc
      781 agctcagcaa tatcagcttc gacggcggca cacaccggaa ccacgaccga accttctttc
      841 gcggcgattt cgcgaacctg gtccagatac gggttatttt caaaaccgtc ttcattgacg
      901 ttagcgatat acattgtcgg cttcagcgtc aggaagctta aataacggat agccgcttta
      961 tcttcgtccg tcaggtccag cgaacgcagc atccccgctt cggccaggtg cggcaggcat
     1021 ttttccagcg cggccagttc cgctttggcg tctttatcgc cgcctttggc tttcttctgt
     1081 acgcgatgga tcgcgcgctc gcaggtatcg aggtcagcca gcgccagctc ggtattgata
     1141 acatcaatat cttctgccgg atttacttta cccgccacgt ggatgatatt gtcgttctca
     1201 aagcagcgaa ccacgtgacc gatagcttcg gtttcacgga tattggtcag gaactggtta
     1261 cccaaccctt cgcctttgga tgcgcctttt accagaccgg cgatatccac gaactccatc
     1321 gtggttggta gaatgcgttg cggtttaaca atctcagcca actggtccag acgcggatcg
     1381 ggcatcggca cgacaccggt attcggttcg atagtgcaga acggaaagtt tgccgcttca
     1441 ataccggctt ttgtcagcgc gttgaacagg gtggatttcc cgacgttggg cagaccgacg
     1501 ataccgcatt tgaatcccat gatttaactc accttaatat cttaataatc aacctgttat
     1561 agaaaacaga ttgcagaaat ggaaataact tcgcctatta tacacggcgt gcggcaaaaa
     1621 tgccgcacat cactggttat tgcgccttaa aggtatgcaa acggcttgtt gctttggcca
     1681 gaccctcttt gaaccacaat tccgtacagc gcgccgcttc gtcaatggcc tcatcaatta
     1741 atttttgttc agaaacaggg ggtttaccca gcacgaaacc aacaacttta tttttatcgc
     1801 ctggatgacc aattccaacg cgtaagcggt gaaagttggg attattgccc agcttgctga
     1861 tgatgtcttt cagaccattg tggccgccgt ggccgccgcc aagtttaaat ttcgcgacgc
     1921 ccggcgggag atccagctcg tcgtgagcga ccagaatttc gtccggctga atacggtaaa
     1981 aactggccat tgcgccaact gctttaccac tgaggttcat gaacgtggtg ggtaccagca
     2041 ggcgaacatc ttccccttcc agcgtgatgc gtgaggtata gccaaagaat ttaggctctt
     2101 cacgcaacgg cgcgcgcagg cgctccgcca gtaaatcgac gtaccatgcg cctgcattgt
     2161 gtcgcgtcgc ggcatattcc gcgccgggat tcgccagacc aacaatcaat ttaattgcca
     2221 cgttttttgt cctgagtaga tccatgactg gcgcgtagtt tactgtctgt ctgcccgctt
     2281 gacaaaacac agcgacactc tgaagtaaat taaataattg ccagcattga ttattaaaaa
     2341 tgtaaactgt tcagagtgtt atttgtaaag ttttgttaaa tgaaacttta catttgtgat
     2401 cgcacccgca cttacaaatg gaagtgttgt ctatacttta cacataaagt ttagggggat
     2461 ttcctaaaaa caacccaaaa gttccggagg tgacatatga aacgcaaaaa cgcttcgtta
     2521 ttcggtaacg tgctgatggg gttggggctg gtcgtgatgg ttgtcggcgt gggttactct
     2581 attttaaacc aactgccgca gtttaatttg ccgcaatttt ttgcgcatgg cgcaatactg
     2641 agcatttttg tcggtgcagt tctttggctg gcgggggctc gtgtaggggg gcatgagcag
     2701 gtgagcgaca aatattagtg ggtacgtcac tatgacaaac gttgccgccg tagcgacaat
     2761 cgtcgtcata gctaaccggt tcaggcccgg taagcgttat cgccaccggg cattgtccat
     2821 taactgagta aatccgctaa cgcctccgtc ctgttcggga agaaggtcag acgtccagga
     2881 atgggtttga taccggcacg cgccattgtg cgcagcggtt ggaactccag gttactgata
     2941 cgcaattcgc aaccctccgg cagacgcttc acaaaacgct gaaaagcatc aagcccgcct
     3001 gcatccagca ctggtactgc gtcccatttc agaacgacga tacgtttgcc cttaatacgt
     3061 gactcaaggt cggtaaacag cccttccgcc gcggcgaaaa agagcggacc gataacacgc
     3121 agcaccagca catcttcagg cacatcgaca ttgaccggcg caagtcgagt cattcgcgca
     3181 atacggcgca taaacagcag ggaagcaagg acaatcccca cgctgatggc gatgaccata
     3241 tcaaacagaa ccgttaatga catgcacagc agcataacga taatgtcatc tttcggcgca
     3301 tggcgtaaca gatccaccac tttatgggct tcactcatat tccatgccac catcagcagt
     3361 agcgccgcca tcgcggaaag cggcagccag gagagtagcg gggctaagac cagtagcgcc
     3421 agaatgacca gaatagcgtg aattaccgcc gagacgggag aggtcgcgcc agcgcggacg
     3481 ttggcggcag agcgggcaat cgcggcggtg gcggtgatgc cgccaaagaa cggcgcgacc
     3541 atattcccca gcccctggcc gataagttcg ctgttagctt tatgtttggt gccggtcatg
     3601 ccgtccagca cgacggcgca gagcaatgat tcgattgccc ccagcattgc catcgagaaa
     3661 gccgctggca gcagcgcgcg cagtgaatcc cagcttagcg taaaatcgga gccaggaagg
     3721 ctccacggca gcatcagttg cggcaggagc tgcgggatgc cgttgccctg agtgccgtca
     3781 gccagaacgt aatggaactg tgagccgata gtcgccacat tgccgcccag cagattaaca
     3841 atccccatta cggcgcaacc ggccagcagc gcgggaaggt gtcccggcag acgaataccg
     3901 agacgcggcc agaaaatcag cgttcccagc gttaccacgc caatggcggc atcgccaata
     3961 ttgacggtgg gcaacgccat aaacagcgcg ccgactttct gcaaatagtg ctctggcaca
     4021 tgggccatct gcagaccaag aaaatcttta atctgcatgg taccgatggt aataccaatc
     4081 cctgaggtaa aacccaacgt gaccgacacc gggatatatt caatcaatcg ccccagtctc
     4141 gccaggccga aaaggatcag gaagaagccc gacatcagcg tggcgaccag taggcccgcc
     4201 agaccaaact gttgcgacac cggatacaaa atcaccacaa acgcggcggt agggccggaa
     4261 acgctaaagc gcgagccgcc ggttagcgcg atcacgatcc cggcgacagc ggaggtatag
     4321 aggccatact gcggcgcaac gccactgcca attgccagcg ccatcgccag cgggatagca
     4381 ataatcccga cggtgatccc ggctatcaca tcacgggtga accgggaggc ggtatatttt
     4441 tctttccagc aagcatcgat gagagcgcgg aaaggcatca catgtgagga aaataatttg
     4501 ttcacaataa tgtttcatcc atgagcgcat catctgtcaa ctaaatggca ggtgaaggag
     4561 gcataagtca tataaaaggg tgttacagac aaaaaaaccc gccgcagcgg gtttcagatc
     4621 cgggttcgat caatgctcga acatggcgga aatcgattct tcgttgctga tacggcgaat
     4681 cgcttcggcc agcatacctg acagggtcaa agtacgcacg ttcggcagcg ctttgatttc
     4741 gtcggtcagc ggaatggtgt cacagacaac gacttcgtca ataacggagt tgcgcaggtt
     4801 gtttgccgca ttgcctgaga agatcgggtg cgtcgcgtag gcaaacacgc gtttagcgcc
     4861 acgttctttc aatgcttctg ctgctttgca cagagtaccg ccggtatcga tcatatcatc
     4921 aaccagcacg cagtcacggc cagcgacgtc gccgatgatg tgcatcacct gagaaacgtt
     4981 cgcgcgcgga cgacgtttat caatgatagc catatcggta tcgttcagca gcttagcgat
     5041 agcgcgggca cgaaccacgc cgccaatatc cggggaaacc acgattgggt tatccagatt
     5101 cagttgcagc atatcttcga gcaggattgg gctaccgaac acgttatcaa ccggaacgtc
     5161 aaagaagccc tggatctgtt cagcatgcag atctacggtg agaacgcggt caacgccgac
     5221 gctggacagg aagtcagcga caacttttgc ggtaatcggc acacgggcgg aacgtacgcg
     5281 acggtcctga cgtgcatagc caaagtaggg gataacggcg gtgatacgac ctgcggaagc
     5341 acgacgcagg gcatcaacca taacgaccaa ttccatcagg ttgtcgttgg ttggggcaca
     5401 agtggactgg atgatgaaaa tatcaccacc gcgtacattt tcgttgattt gtacgctgac
     5461 ttcgccgtcg ctaaagcgac ctacggcggc gtcgccgaga gaagtgtaca ggcggttggc
     5521 aatacgttgt gctagttccg gggtggcgtt accagcaaaa agcttcatat caggcacgag
     5581 aagaacctca ggcatgcgtc cattggtgga aagaatctgc cgaaaactgt gcgggccagg
     5641 caaaatccta tccaggcggt gtattaaaga gcgcgatgca acgtctggaa caaggtgacg
     5701 ttgtcaccga agctcagctt gcccggctta ctcgtcttca ttcacgtttc atgtgcgctg
     5761 gtatcaatgc ctcacaccgg tcaaatacgg catatatgac cggcgactcg tcatttcgcc
     5821 atcttcctga aacccgaatg cgttagagta actctcgatg caatggggaa aggttaacac
     5881 ccttcgccac aaaagcattg agccattccg gggcttgctc aagcacctgg cgagcacaag
     5941 actctgtatc gaattcagca aagacacagg cccctgtccc agtcaggcgc gacggcgcgt
     6001 attctaacag ccaggaaagc gccgcatcaa cctcgcgaaa acgttttctt gcgataacct
     6061 cgcaatcatt gctgaattca cattttagta acgtatctat tgaccttttt ggcgtattac
     6121 gcggcaattg aggatcttta aagataactg gcgtcggaat gcttacgcca gggtgcgcga
     6181 ccagatacca tttttccggc ggattcaccg gcgttaatat ttcgcctacg ccttcggcaa
     6241 acgcggcgtg gccacgaaca aagaccggga cgtcggcgcc gagcgtcagg ccgagcgtcg
     6301 ccagttcatc aatggaaagc ccgcattgcc aaagatgatt gagcgccacc agaacggtcg
     6361 cggcgttaga cgagccgcca cccagaccgc cgcccatggg aaggcgcttc tcaatgctga
     6421 tatccgcgcc gcttccggcg ggcaggcgtc cactctccga ggcgactttc atcaacagcc
     6481 gcgcggcgcg gacgatcaga ttgtcttcat tttcaacgcc ggttaccggc gttaataaat
     6541 ggatttcgcc atcgtgacgc ggttcgatgt ggagtgtgtc gccataatcc agaaactgaa
     6601 acagcgtctg cagcgtgtgg tagccgtctg cacgctgtcc ggtgatatat aaaaacagat
     6661 ttaattttgc cggagaaggc caatgggtca tcatttcaca atccagttat ccattttcag
     6721 cttaatgcgc tgactgccat ctgaaagctc catattggct ggcatggcag gctgcgtttt
     6781 gctgtcatag ccaccgtaaa ccactttcca gtttttacca tcctggtggt agttcacttc
     6841 gctcaggcgg tactggtcgt ccagtttgta gtcggtggca tcgccaggca gaccgaggat
     6901 ccactgccgc aggctgttta acggaatcgg catcccggtg agtttgccga tcatctcttc
     6961 ggcgtcatcg gcggtataac gctggccttt gttatccacc aactggacgt tgcccggctg
     7021 ggcgttaagc tccagctcgg tgctgcccag cgggttggta agcagcaggc ggtagcgatc
     7081 ctgtccggtc tgttgccaga agaagcgcgc atagactttc tgatcatctg agatgtaagc
     7141 aaaggcgccg cgcgtctggt attgattcag atgacgcacc tcttgctgat gctggcgcca
     7201 ctgaggggaa tccgggctct tgcccgggcc tttatgccca ggaagcgtac aggcggtgag
     7261 aaccaggctt gctaacggca gtagacgaat caggcgaaaa tcgggcaggg tcatagtgat
     7321 gacgaatcct tgtgatacgg tgcaataatt gcctgaaggc gttacgctta tcaggcctga
     7381 aaactgaacc ggcaagctgt aaaaacgttc gcgccgcgat tcggcaaatt tttgctatcg
     7441 gttacagtta tagcctttaa tgctagcgcc gcctggtgac atcgtctact ttcaagttgt
     7501 cttaaatcat caaattagcg agcgctgcca attactccaa aagggggctc tctcttttat
     7561 tgaccacgcg catcctgtat gatgcaagca gactaaccat atcaacgctg gtactactcc
     7621 cgcagacatg acccttttag cactcggtat taaccataaa acggcacctg tatcgctgcg
     7681 agaacgcgta acgttttcgc cggacacgct tgatcaggcg ctggacagcc tgcttgcgca
     7741 gccaatggtg cagggcgggg tcgtgctgtc aacctgtaac cgtacagagc tgtatttgag
     7801 cgtggaagag caggataacc tgcaagaagc gctgatccgc tggttatgcg attaccataa
     7861 cctgaacgag gacgatctgc gcaacagtct gtactggcat caggacaatg acgccgtcag
     7921 ccacctgatg cgcgtcgcca gcggtctgga ttcactggtg ctgggcgaac cgcaaatcct
     7981 cggtcaggtg aaaaaagcgt ttgcggattc gcaaaaaggc caccttaacg ccagcgcgct
     8041 ggagcgaatg tttcagaagt ctttttccgt cgccaagcga gtgcggactg aaaccgatat
     8101 cggcgccagc gccgtctccg tcgcgtttgc cgcctgtacg ctcgcccgcc aaatctttga
     8161 atcgctctcg acggtcactg tactgttagt tggcgcgggc gaaactattg aactggtggc
     8221 gcgtcacctg cgcgagcata aagtacaaaa gatgattatc gccaaccgaa cccgcgagcg
     8281 cgcgcaagcc ctggcggatg aggttggcgc tgaggttatc tcgctcagcg atatcgacgc
     8341 ccgcttgcag gatgccgata ttatcatcag ttcgaccgcc agcccgctgc cgattatcgg
     8401 taaaggcatg gtggagcgcg cattaaaaag ccgtcgcaac cagccgatgc tgctggtgga
     8461 tatcgccgta ccgcgcgacg ttgagccgga agtcggcaaa ctggcgaacg cttatcttta
     8521 tagcgtcgat gatttacaga gcatcatttc gcataatctg gcgcagcgtc aggctgcggc
     8581 ggtggaagcg gaaacgattg ttgagcagga agccagcgag tttatggcct ggctacgcgc
     8641 ccagggggcc agcgagacca ttcgggaata ccgtagtcag tcggagcaga ttcgtgacga
     8701 actgactacc aaagcgctgt cggcccttca acagggcggt gatgcgcaag ccatcttgca
     8761 ggatctggca tggaaactga ccaaccgcct gattcatgcg ccaacgaaat cacttcaaca
     8821 ggctgcccgt gacggggatg acgaacgcct gaatattctg cgcgacagcc tcgggctgga
     8881 gtagcagcac acaccacact tttttacagg gtgaatttac gcctatgaag ccttctatcg
     8941 ttgccaaact ggaagccctg cacgaacgcc atgaggaagt tcaggcgttg ctgggcgatg
     9001 cgggaattat cgccgaccag gaccgctttc gcgcattgtc gcgcgaatat gcgcaattaa
     9061 gcgacgtttc tcgctgtttt acggactggc aacaggttca ggacgatatc gagacggctc
     9121 agatgatgct cgacgatcct gaaatgcggg aaatggcgca ggaagaactg cgcgaagcga
     9181 aagaaaaaag cgaacaactg gagcaacagt tacaggtact gctgctgccg aaagatccgg
     9241 acgatgaacg aaacgcgttc cttgaggttc gcgccggcac tggcggcgac gaagccgcgc
     9301 tgtttgccgg cgatctgttc cgcatgtaca gccgttatgc cgaagcgcgc cgctggcgcg
     9361 tggagatcat gagcatgagc gaaggcgagc atggcggtta taaagagatc atcgccaaaa
     9421 tcagcggcga cggcgtgtat ggccgactga aatttgagtc cggcggacac cgcgtacagc
     9481 gtgttccggc gaccgagtcg caggggcgta tccatacctc cgcctgtacc gtcgccgtga
     9541 tgccggagct gccggaagcc gagctgccgg atattaaccc ggcggatctg cgcattgata
     9601 cgtttcgttc ttccggcgcg ggcggtcagc acgttaacac caccgactcc gctatccgta
     9661 ttacccactt gccgaccggc atcgtggtgg aatgccagga cgagcgttcg cagcataaaa
     9721 acaaagcgaa agcgctctcg gtgctcgggg cgcgcattca cgccgccgaa acggcaaaac
     9781 gccagcaggc cgaggcgtca acgcgccgca acctgcttgg cagcggcgat cgcagcgatc
     9841 gtaaccggac ctataatttc ccgcaggggc gcgtgaccga tcatcgtatt aatctgacgt
     9901 tatatcgcct tgatgaaacg atggaaggta agctggatat gctgattgag ccgattgttc
     9961 aggaacacca ggctgacctg ttagccgcgt tgtccgagca ggaataatgg attttcagca
    10021 ctggctacat gaggcggtaa accagctccg ggacagcgac agcccccggc gcgacgccga
    10081 gatcctgctt gagtacgtta cgggcaagag gcggacgtat atcatggcct ttggcgaaac
    10141 gccgcttacc gatgtccagc aacaacagct cgcggagctg ctgcagcggc gtaaacaggg
    10201 cgaacccatt gcgtacctga cgggcttacg cgaattttgg tcgctgccgc tcttcgtttc
    10261 tcccgccacg ctaatcccgc gcccggatac cgaatgtctg gttgaacagg cgttggcgcg
    10321 attgccggtc aaaacctgtc gtattctgga tttaggcacc ggaaccggcg cgattgcgct
    10381 ggcgctggcc tgcgagcgac cggattgcga ggtgactgcg gtcgatcgta tgcctgatgc
    10441 ggttgcgctg gcgatacgca acgcggaaca tttggctatc cggaatgtgc gtatactgca
    10501 aagttgttgg ttcagcgcac tatcggggca gcagttcgac atgattgtca gcaatccgcc
    10561 ctacattgac gcgcaggacc cgcaccttag cgaaggcgat gtacgctttg aaccgcgctc
    10621 agcgttggtg gcggacgaaa acggtatggc ggatcttacg catattatcg ataatgcccg
    10681 ccagatgtta acgcccggcg gcttcctgct gctggaacac ggttggcggc agggcgaagc
    10741 ggtaagagcg gctttcaggc ggtctggtta cacggatgta gaaacgtgtc gtgattatgg
    10801 tggcaatgaa cgcgtggcct gcgggcgttt tacgccatga caattgcaat gttgctcacg
    10861 cttcatctta tttgtgttgc gctctccgtc agtttgtttg tcgctcgtta ctggtggcgc
    10921 tattgcggcc atgcgttggc cgccgcgcgc tggacacgaa tcgtgcctcc cgtcatagat
    10981 accctgttac tgcttagcgg tattgggtta atcgttaaaa cgcacatcct gccattcacg
    11041 gagtcgggct catggctgac tgaaaaactg tttggcgtta tcatctacat cgttttgggt
    11101 tttattgcgc ttgattatcg tcaggcgcgc agccagcagg cgcgttttat cgctttcccg
    11161 ctggcgctgg tggtgctgta catcatcatt aaactcgcca ccacaaaaat accgttactg
    11221 gggtaagtca tgaggtcgtt agctgatttc gaatttaaca atgcgccgct gtgtgatggc
    11281 atgatcctgg catcagagat gattcgcctg gattttccca cgcagtttgt ctacgacgaa
    11341 ctggaacgtc tggtcagtct ggcgcaggaa gaaattagcc agctcctgtc tcaggatgag
    11401 caactggaaa aattgctggc acttttttac ggcgagtggg ggttcacgga ttcccgcggc
    11461 gtctaccgtc tttctgatgc tttatggctc gataaagtcc tgaaaaaacg ccaggggagc
    11521 gctgtatcgt tgggcgctat tttattatgg atagcaaacc gtcttgattt gccgttggtg
    11581 cccgttatct tcccaacgca gctgattttg cgtattgaat cgctggaagg agaaatgtgg
    11641 ctgattaacc cgttcaacgg tgaaacgctt gatgaacata ccctcgaagt ctggttaaaa
    11701 ggcaatatta gtccggtcgc cgagttgttt aacgaagatt tggacgaagc ggataacgcc
    11761 gaagtgattc gtaagctact ggatacgctg aaatcctcgc tgatggagga acggcaaatg
    11821 gagctggcgc tgcgcgttag cgaagcattg ttgcaattta acccggaaga tccttacgaa
    11881 atccgtgacc gcgggttgat ctacgcgcag cttgagtgtg aacacgttgc gctgactgat
    11941 ttaagctact tcgttgaaca gtgtccggaa gacccgatca gcgaaatgat tcgtgcgcag
    12001 atcaacacca ttgcgcacaa gcaaattgtt ctacattaat taaccgacat tttacctata
    12061 agtgtaaggc gatcctatga aacaaaaagt ggttaacatt ggcgacatta aggtggcaaa
    12121 tgacctgccg tttgtgctgt ttggcggtat gaacgtgctg gagtcacgcg atctggcaat
    12181 gcgcatttgt gagcactacg taaccgttac ccagaagctg ggtattcctt acgtgttcaa
    12241 ggcctctttt gataaagcca accgttcctc tattcactct taccgtgggc cgggtctgga
    12301 agaagggatg aaaatcttcc aggaactcaa acagacattt ggcgtaaaag tgatcactga
    12361 cgtccatgaa gccagccagg cgcagcctgt ggctgatgtg gttgacgtga ttcagctccc
    12421 ggcgtttttg gcgcgccaga ccgacctggt ggaagcgatg gcgaaaaccg gcgctgtgat
    12481 taacgtgaaa aagccgcagt ttgtaagccc gggtcagatg ggcaatatcg tggataagtt
    12541 ccatgagggc ggtaacgata aggtgattct gtgcgatcgc ggcgcgaact tcggttatga
    12601 caacctggtg gtggatatgc tgggctttag cgtgatgaaa aaggtctccg gcaactcgcc
    12661 ggtgattttc gacgttaccc atgcgctgca atgccgcgac ccatttggcg ctgcctcggg
    12721 cggtcgtcgt ggtcaggtga ccgagctggc gcgcgccggt atggctgtcg gtctggcggg
    12781 cctgttcctg gagtcgcatc cggacccggc taacgcgaag tgcgacggtc cttccgcgct
    12841 gccgctggcg aaactggagc agttcctgac ccagataaaa gcgattgatg atttggtgaa
    12901 aagcttcgac gagctggata ccgagaactg attgcggttt ttagcttgtg taggccggat
    12961 aagatactat ccgg
//
LOCUS       DAJVBX010000133        12918 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.133, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000133 DAJVBX010000000
VERSION     DAJVBX010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 12918)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12918)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12918
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.133"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..372
                     /gene="tuf"
                     /locus_tag="OPV72_003128"
     CDS             <1..372
                     /gene="tuf"
                     /locus_tag="OPV72_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312217.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HCR9915352.1"
                     /translation="GENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKD
                     EGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGL
                     RFAIREGGRTVGAGVVAKVLG"
     gene            602..985
                     /gene="secE"
                     /locus_tag="OPV72_003129"
     CDS             602..985
                     /gene="secE"
                     /locus_tag="OPV72_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007665874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HCR9915353.1"
                     /translation="MSANTEAQGSGRGLEAMKWIVVAILLIVAIVGNYLYRDMMLPLR
                     ALAVVILIAAAGGVALLTTKGKATVAFAREARTEVRKVIWPTRQETLHTTLIVAAVTA
                     VMSLILWGLDGILVRLVSFITGLRF"
     gene            987..1532
                     /gene="nusG"
                     /locus_tag="OPV72_003130"
     CDS             987..1532
                     /gene="nusG"
                     /locus_tag="OPV72_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005280494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HCR9915354.1"
                     /translation="MSEAPKKRWYVVQAFSGFEGRVATSLREHIKLHNMEELFGEVMV
                     PTEEVVEIRGGQRRKSERKFFPGYVLVQMVMNDASWHLVRSVPRVMGFIGGTSDRPAP
                     ISDKEVDAIMNRLQQVGDKPRPKTLFEPGEMVRVNDGPFADFNGVVEEVDYEKSRLKV
                     SVSIFGRATPVELDFSQVEKA"
     gene            1690..2118
                     /gene="rplK"
                     /locus_tag="OPV72_003131"
     CDS             1690..2118
                     /gene="rplK"
                     /locus_tag="OPV72_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006121495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HCR9915355.1"
                     /translation="MAKKVQAYVKLQVAAGMANPSPPVGPALGQQGVNIMEFCKAFNA
                     KTDSIEKGLPIPVVITVYADRSFTFVTKTPPAAVLLKKAAGIKSGSGKPNKDKVGKIS
                     RAQLQEIAQTKAADMTGADIEAMTRSIEGTARSMGLVVED"
     gene            2122..2826
                     /gene="rplA"
                     /locus_tag="OPV72_003132"
     CDS             2122..2826
                     /gene="rplA"
                     /locus_tag="OPV72_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HCR9915356.1"
                     /translation="MAKLTKRMRVIREKVDATKQYDINEAIALLKELATAKFNESVDV
                     AVNLGIDARKSDQNVRGATVLPHGTGRSVRVAVFTQGPNAEAAKAAGAELVGMEDLAD
                     QIKKGEMNFDVVIASPDAMRVVGQLGQVLGPRGLMPNPKVGTVTPNVAEAVKNAKAGQ
                     VRYRNDKNGIIHTTIGKVDFDADKLKENLEALLVALKKAKPSQAKGVYIKKVSISTTM
                     GAGVAVDQAGLSASAN"
     gene            3242..3739
                     /gene="rplJ"
                     /locus_tag="OPV72_003133"
     CDS             3242..3739
                     /gene="rplJ"
                     /locus_tag="OPV72_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002438625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HCR9915357.1"
                     /translation="MALNLQDKQAIVAEVSEVAKGALSAVVADSRGVTVDKMTELRKA
                     GREAGVYMRVVRNTLLRRVVEGTQFECLKDTFVGPTLIAYSMEHPGAAARLFKEFAKA
                     NAKFEVKAAAFEGELIPASQIDRLATLPTYEEAIARLMATMKEASAGKLVRTLAAVRD
                     AKEAA"
     gene            3806..4171
                     /gene="rplL"
                     /locus_tag="OPV72_003134"
     CDS             3806..4171
                     /gene="rplL"
                     /locus_tag="OPV72_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HCR9915358.1"
                     /translation="MSITKDQIIEAVSAMSVMDVVELISAMEEKFGVSAAAAVAVAAG
                     PAEAAEEKTEFDVILKAAGANKVAVIKAVRGATGLGLKEAKDLVESAPAALKEGVSKD
                     DAEALKKSLEEAGAEVEVK"
     gene            4489..8517
                     /gene="rpoB"
                     /locus_tag="OPV72_003135"
     CDS             4489..8517
                     /gene="rpoB"
                     /locus_tag="OPV72_003135"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004870488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HCR9915359.1"
                     /translation="MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPE
                     GQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDVQECQIRGVTYSAPLRVKLRL
                     VIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSD
                     KGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTE
                     QILDLFFEKVVFEIRDNKLQMELIPERLRGETASFDIEANGKVYVEKGRRITARHIRQ
                     LEKDDIKHIEVPVEYIAGKVVSKDYVDESTGELICAANMELSLDLLAKLSQSGHKRIE
                     TLFTNDLDHGPYISETVRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSE
                     DRYDLSAVGRMKFNRSLLRDEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGN
                     RRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGS
                     SQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEG
                     PNIGLINSLSVYAQTNEYGFLETPYRRVVDGVVTDEIHYLSAIEEGNYVIAQANSNLD
                     DEGHFVEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMG
                     ANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGGTVQYVDASRIVIKVNEDE
                     MYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQ
                     NMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPN
                     VGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVK
                     DSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSEELQILEAGLF
                     SRIRAVLVSGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLE
                     AKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYD
                     ENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINAMLKQQQEVAKLREFIQ
                     RAYDLGADVRQKVDLSTFSDDEVLRLAENLRKGMPIATPVFDGAKEAEIKELLKLGDL
                     PTSGQITLFDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGK
                     AQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMP
                     ESFNVLLKEIRSLGINIELEDE"
     gene            8594..12817
                     /gene="rpoC"
                     /locus_tag="OPV72_003136"
     CDS             8594..12817
                     /gene="rpoC"
                     /locus_tag="OPV72_003136"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HCR9915360.1"
                     /translation="MKDLLKFLKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETI
                     NYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERM
                     GHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQIL
                     TEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECETLREELNETNSETKRKKLT
                     KRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRN
                     NRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGK
                     QGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLAT
                     TIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLH
                     PLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVL
                     GLYYMTRDCVNAKGEGMVLTGPKEAERIYRAGLASLHARVKVRITEYEKDENGEFVAH
                     TSLKDTTVGRAILWMIVPKGLPFSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQT
                     MYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKV
                     IDIWAAANDRVSKAMMDNLQTETVINRDGQEEQQVSFNSIYMMADSGARGSAAQIRQL
                     AGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTR
                     RLVDVAQDLVVTEDDCGTHEGILMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTADI
                     LVPRNTLLHEQWCDLLEANSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEA
                     IGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAESSIQVKNKGSIKLSNVKSVVNSSGK
                     LVITSRNTELKLIDEFGRTKESYKVPYGAVMAKGDGEQVAGGETVANWDPHTMPVITE
                     VSGFIRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTTGGKDLRPALKIVDAQGNDV
                     LIPGTDMPAQYFLPGKAIVQLEDGVQISSGDTLARIPQESGGTKDITGGLPRVADLFE
                     ARRPKEPAILAEIAGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERV
                     ERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLR
                     KATIESAGSSDFLEGEQVEYSRVKIANRELEANGKVGATFSRDLLGITKASLATESFI
                     SAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAAGEQ
                     PATPQVTAEDASASLAELLNAGLGGSDNE"
BASE COUNT         3135 a         3259 c         3607 g         2917 t
ORIGIN      
        1 ggtgagaacg taggtgttct gctgcgtggt atcaaacgtg aagaaatcga acgtggtcag
       61 gtactggcta agccgggcac catcaagccg cacactaagt tcgaatctga agtgtacatt
      121 ctgtccaaag atgaaggcgg ccgtcatact ccgttcttca aaggctaccg tccgcagttc
      181 tacttccgta ctactgacgt gactggtacc atcgaactgc cggaaggcgt agagatggta
      241 atgccgggcg acaatatcaa aatggttgtt accctgatcc acccgatcgc aatggacgac
      301 ggtctgcgtt tcgcaatccg tgaaggcggc cgtactgttg gcgcgggcgt tgttgctaaa
      361 gttctcggct aatcgctgat aacatttgac gcaatgcgca ataaaagggc atcatttgat
      421 gccctttttg cacgctttca caccagaacc tggctcatca gtgattttat ttgtcataat
      481 cattgctgag acaggctctg tagagggcgt ataatccgaa aggcgaataa gcgtttcgat
      541 ttggtttgcc tcgcgattgc ggggtgaaaa tgtttgtaga atacttctga caggttggtt
      601 tatgagtgcg aataccgaag ctcaagggag cgggcgcggc ctggaagcga tgaagtggat
      661 agttgttgcc atattgctga tcgtcgcaat cgtcggcaac tacctctatc gcgacatgat
      721 gctgccgctg cgtgcgctgg ccgtagtaat tctgattgct gcagcgggtg gtgtcgcgct
      781 gttgacgaca aaaggtaaag caaccgttgc ttttgcccgt gaagcgagaa ccgaagtccg
      841 taaggtcatt tggccgactc gccaggaaac gctgcacacc acgctgatcg tcgctgcggt
      901 taccgcagtt atgtcactga tcctgtgggg actggatggt attctggttc gcctggtatc
      961 ctttatcact ggcctgaggt tctgagatgt ctgaagcacc taaaaagcgc tggtacgtcg
     1021 ttcaggcgtt ttccggtttt gaaggccgcg tagccacatc gctgcgcgag catatcaaat
     1081 tacacaatat ggaagagctg tttggcgaag tcatggtgcc gactgaagaa gtcgttgaga
     1141 tccgtggcgg ccagcgtcgc aaaagcgaac gcaaattctt cccgggttac gttctggtcc
     1201 agatggtcat gaacgacgca agctggcacc tggtgcgcag cgtgccgcgt gtgatgggct
     1261 ttatcggcgg tacctctgac cgtccggcgc cgatcagcga caaagaagtc gatgcgatca
     1321 tgaaccgcct gcagcaggtt ggcgataagc cgcggccgaa aacgttgttt gaaccgggtg
     1381 aaatggttcg tgttaacgac ggtccgttcg cagactttaa cggcgttgtc gaagaagtcg
     1441 attatgagaa gtctcgcctg aaagtgtctg tttctatctt cggtcgtgcg accccggtag
     1501 agctggactt cagccaggtt gagaaagcgt aaggctgcga tcaaaaaagc agcgatctaa
     1561 tcgttgcata gggcgcaaaa ttgacataca atttcgcgcc ttttgttttt atgggcctta
     1621 tgcccataaa gcgatattta tcacggggag cttctttgaa gcgatactac ccaattcgag
     1681 gaatttagaa tggctaagaa agtacaagcc tatgtcaagc tgcaggttgc agctggtatg
     1741 gcgaacccga gtccgccggt tggtccagca ctgggtcagc agggtgtgaa catcatggaa
     1801 ttctgcaaag cgttcaacgc aaaaacggat tccatcgaaa aaggtctgcc gattccggtt
     1861 gttattaccg tttacgctga ccgttctttc accttcgtta ccaaaacgcc tccggcagct
     1921 gttctgctga aaaaagcggc tggtatcaag tctggttccg gcaagccgaa caaagacaaa
     1981 gtaggtaaaa tttcccgcgc tcagctgcag gaaatcgcgc agaccaaagc tgccgacatg
     2041 accggtgccg acattgaagc gatgactcgc tccatcgaag gtactgcacg ttccatgggc
     2101 ctggtagtgg aggactaaga aatggctaaa ctgaccaagc gtatgcgcgt gatccgtgaa
     2161 aaagttgatg cgaccaaaca gtacgacatc aacgaagcta ttgccctgtt gaaagagctg
     2221 gccactgcta aattcaacga aagcgttgac gttgccgtta acctcggcat cgacgctcgt
     2281 aaatctgacc agaacgttcg tggcgcgact gtactgccgc acggtactgg ccgttctgtt
     2341 cgcgttgccg tatttaccca gggcccgaac gctgaagcag ctaaagctgc tggcgctgag
     2401 ctggtaggta tggaagatct ggctgaccag atcaagaaag gcgaaatgaa cttcgacgtt
     2461 gttatcgcat ccccggatgc aatgcgcgtt gttggccagc tgggccaggt tctgggtccg
     2521 cgcggcctga tgccaaaccc gaaagtcggt accgtaacgc cgaacgttgc tgaagcggtt
     2581 aagaacgcta aagcaggtca ggttcgttac cgtaacgaca aaaacggcat catccacacc
     2641 accatcggta aagtggactt tgacgctgac aaactgaaag aaaacctgga agctctgctg
     2701 gttgcgctga aaaaagcaaa accgagccag gcgaaaggcg tgtacatcaa gaaagttagc
     2761 atctccacca ccatgggtgc tggcgttgcc gttgatcagg ctggtctgag cgcatctgcg
     2821 aactaagatt agtctttacg tgggcggtga ttttgtctac aatcttaccc ccacgtattc
     2881 tgctagttgc agacgtatat ccgaggtatt cgggttgtga caaggcggca acttagtgag
     2941 tcgccaggag catagttaac tatgtgactg gtgcgaacga aggaagccaa cgccgtcaca
     3001 agctgaatag cgacggatag aaaagatttg ttcgttggag cctggcctat ccaggcctcc
     3061 gtcgaagacc gcaggcgtct cgcaagaggc ttaatcccct gcgtagacgg tgacagaacg
     3121 ctaagattat ttttgatact ctggcttgtt tctgctcacc gtattaagac gctcttctcg
     3181 ttgagatgag tgaagtgagt tccggaacat gagttccggc aaacatccag gagcaaagct
     3241 aatggcttta aatcttcaag acaaacaagc gattgttgct gaagtcagcg aagtagccaa
     3301 aggcgcgctg tctgcagtag ttgcggattc ccgtggcgta actgtagata aaatgactga
     3361 actgcgtaaa gcaggtcgtg aagctggcgt atacatgcgt gttgttcgta acaccctgct
     3421 gcgccgcgtc gttgaaggta ctcagttcga gtgcctgaaa gacacgtttg ttggtccgac
     3481 cctgattgca tactctatgg aacacccggg cgctgctgct cgtctgttca aagagttcgc
     3541 gaaagcgaat gcaaaatttg aggtcaaagc tgcagccttt gaaggtgagc tgatcccggc
     3601 gtctcagatc gaccgcctgg caactctgcc gacctacgaa gaagcaattg cacgcctgat
     3661 ggcaaccatg aaagaagctt cggctggcaa actggttcgc acactggctg ctgtacgcga
     3721 tgcaaaagaa gctgcgtaat cgcagttgtc tttatcaagc atttgcttac gtataaactt
     3781 attctgatat tcaggaacaa tttaaatgtc tatcactaaa gatcaaatca ttgaagcagt
     3841 atccgctatg tccgtaatgg acgttgtaga actgatttct gcaatggaag aaaaattcgg
     3901 tgtttccgct gctgctgctg tagctgtagc tgctggcccg gctgaagctg ctgaagaaaa
     3961 aactgaattc gacgtaattc tgaaagctgc tggcgctaac aaagttgctg ttatcaaagc
     4021 agtacgtggc gcaactggcc tgggtctgaa agaagctaaa gacctggtag aatctgctcc
     4081 ggccgctctg aaagaaggcg tgagcaaaga tgacgctgaa gcactgaaaa aatctctgga
     4141 agaagctggc gctgaagttg aagttaaata agccaaccct tccggttgca gcctgagaaa
     4201 tcaggctgat ggctggtgac tttttagtca ccagcctttt tgcgctgtaa ggcgccagta
     4261 gcgtttcaca ctgtttgact actgctgtgc ctttcaatgc ttgtttctat cgacgactta
     4321 atatactgcg acagagcgta cgttctgtgt aaatcgcaat gaaatggttt aagcgtgata
     4381 gcaacaggca ttgcggaaag tatccatttt ccggtcaaca aaatagtgtt gcacaaactg
     4441 tcccccgcag gacagatggg tcgacttgtc agcgagctga ggaaccctat ggtttactcc
     4501 tataccgaga aaaaacgtat tcgtaaggat tttggtaaac gtccacaagt tctggatgta
     4561 ccttatctcc tttctatcca gcttgactcg tttcagaagt ttatcgagca agatcctgaa
     4621 gggcagtacg gcctggaagc agccttccgt tccgtgttcc cgattcagag ctacagcggt
     4681 aattccgagc tgcagtacgt cagctaccgc cttggcgaac cggtgtttga cgttcaggaa
     4741 tgtcagatcc gtggcgtgac ctattccgca ccgctgcgcg taaaactgcg tctggtgatc
     4801 tacgagcgcg aagcgccgga aggcaccgtt aaagacatta aagaacaaga agtctacatg
     4861 ggcgaaattc cgctcatgac cgacaacggt acctttgtta tcaacggtac tgagcgtgtt
     4921 atcgtttctc agctgcaccg tagtccgggc gtcttctttg actccgacaa aggtaaaact
     4981 cactcttcgg gtaaagtgct gtataacgcg cgcatcattc cttaccgtgg ttcctggctg
     5041 gacttcgaat tcgatccgaa ggacaacctg ttcgtgcgta tcgaccgtcg ccgtaaactg
     5101 cctgcgacca tcatcctgcg tgcgctgaac tacaccactg agcagatcct tgacctgttc
     5161 tttgagaaag tcgtcttcga aattcgcgac aacaagctgc agatggagct gattccagaa
     5221 cgtctgcgcg gcgaaaccgc gtcgttcgat atcgaagcta acggcaaggt gtacgttgaa
     5281 aaaggccgtc gcattaccgc gcgtcatatc cgtcagctgg aaaaagacga tatcaagcat
     5341 atcgaagttc cggttgagta catcgcaggt aaagtcgtct ctaaagacta cgttgacgaa
     5401 tctactggcg agctgatctg cgcggcgaac atggagctga gcctggatct gctggctaag
     5461 ctgagccagt ccggccacaa gcgtatcgaa acgctgttta ccaacgatct ggaccacggc
     5521 ccgtacattt ctgaaacggt acgcgtcgat ccaactaacg atcgtctgag cgcgctggta
     5581 gaaatctacc gcatgatgcg ccctggtgag ccgccgacac gcgaagcggc tgaaagcctg
     5641 tttgagaacc tgttcttctc cgaagaccgc tatgacctgt ctgcggtggg tcgtatgaag
     5701 ttcaaccgtt ctctgctgcg cgacgaaatc gaaggttccg gtatcctgag caaagacgac
     5761 atcattgatg tcatgaagaa gctcatcgat atccgtaacg gtaaaggcga agtggatgat
     5821 atcgaccacc tcggcaaccg tcgtatccgt tccgtcggcg aaatggcgga aaaccagttc
     5881 cgcgttggcc tggtgcgtgt agagcgtgcg gtgaaagagc gtctgtctct gggcgatctg
     5941 gataccctga tgcctcagga tatgatcaac gccaagccga tttccgccgc agtgaaagag
     6001 ttctttggtt ccagccagct gtctcagttt atggaccaga acaacccgct gtctgagatt
     6061 acgcacaaac gtcgtatctc cgcactcggc ccaggcggtc tgacccgcga acgcgcaggc
     6121 ttcgaagttc gagacgtaca cccgacgcac tacggtcgcg tatgtcctat cgaaacgccg
     6181 gaaggtccga acatcggtct gatcaactcc ctgtccgtgt acgcacagac taacgaatat
     6241 ggcttccttg agacgccgta ccgtcgtgtg gttgatggcg tggttactga cgaaattcat
     6301 tacctgtctg ctatcgaaga aggcaactac gttatcgctc aggcgaactc caacctggat
     6361 gacgaaggcc actttgtaga agatctggta acctgccgta gcaaaggcga atccagcttg
     6421 ttcagccgcg accaggttga ctacatggac gtttccaccc agcaggtggt ctccgtcggt
     6481 gcgtccctga tcccgttcct ggaacacgat gacgccaacc gtgcattgat gggtgcgaac
     6541 atgcaacgtc aggcggttcc gactctgcgt gctgataagc cgctggtggg taccggtatg
     6601 gaacgtgctg tcgccgtcga ctccggtgtt actgcagtag ctaaacgtgg cggtactgtt
     6661 cagtacgtgg atgcatcccg tatcgttatc aaagttaacg aagacgagat gtacccgggt
     6721 gaagcaggta tcgacatcta taacctgacc aaatacaccc gctctaacca gaacacctgt
     6781 atcaaccaga tgccatgtgt gtctctgggc gagccggttg aacgcggcga cgtgctggca
     6841 gacggtccgt ccaccgacct cggtgaactg gcgctcggtc agaacatgcg cgtggcgttc
     6901 atgccgtgga acggctacaa cttcgaagac tccatcctcg tttccgagcg tgttgtccag
     6961 gaagaccgtt tcaccaccat ccacattcag gaactggcgt gcgtgtcccg tgacaccaag
     7021 ctggggccgg aagagatcac cgctgacatc ccgaacgtgg gtgaagctgc gctctccaaa
     7081 ctggatgaat ccggtatcgt ttacatcggc gcggaagtga ctggcggcga cattctggtc
     7141 ggtaaggtaa cgccgaaagg tgaaacccag ctgacgccgg aagagaaact gctgcgtgcg
     7201 atcttcggtg agaaagcgtc tgacgttaaa gactcttctc tgcgcgtacc taacggtgtc
     7261 tccggtacgg ttatcgacgt tcaggtcttt actcgcgatg gcgtagaaaa agacaaacgt
     7321 gctctggaaa tcgaagagat gcagctcaag caggcgaaaa aagacctgtc tgaagaactg
     7381 cagatcctcg aagcgggcct gtttagccgt atccgtgcgg tgttggtgtc cggcggcgtt
     7441 gaagctgaga agctcgacaa actgccgcgc gaccgctggc tggaactcgg tctgaccgac
     7501 gaagagaaac aaaatcagct ggaacaactg gctgagcagt atgacgaact gaaacacgag
     7561 ttcgagaaaa aacttgaagc gaagcgccgt aaaatcaccc agggcgacga tctggcgccg
     7621 ggcgtgctga agatcgtgaa ggtctatctg gccgttaaac gccgtatcca gccgggtgat
     7681 aagatggcag gtcgtcacgg taacaagggt gttatctcta agatcaaccc gatcgaagac
     7741 atgccttacg atgaaaacgg cacgccggta gacatcgtac tgaacccgct gggcgtaccg
     7801 tctcgtatga acatcggtca gattctggaa acccacctgg gtatggctgc gaaaggtatt
     7861 ggcgacaaga ttaacgccat gctgaaacag cagcaggaag tcgcgaaact gcgcgaattc
     7921 atccagcgtg cctacgatct gggcgccgac gttcgtcaga aagtcgacct gagcaccttc
     7981 agcgatgatg aagtgctgcg tctggcagaa aacctgcgca aaggtatgcc gattgccaca
     8041 ccagtgttcg acggtgcgaa agaagcggaa atcaaagagc tgctgaaact gggcgacctg
     8101 ccgacctccg gtcagatcac cttgttcgat ggccgtacgg gtgaacagtt cgaacgtccg
     8161 gtaaccgtcg gttacatgta catgctgaaa ctgaaccacc tggttgatga caagatgcat
     8221 gcgcgttcta ccggttctta cagcctggtt actcagcagc cgctgggtgg taaggcgcag
     8281 ttcggtggtc agcgcttcgg ggagatggaa gtgtgggcgc tggaagctta cggcgccgcc
     8341 tacaccctgc aggaaatgct caccgttaag tctgatgacg tgaacggtcg taccaagatg
     8401 tataagaaca tcgtggacgg caaccatcag atggaaccgg gtatgccgga atccttcaac
     8461 gttctgttga aagagatccg ctcgctgggc atcaacatcg aactggaaga cgagtaattc
     8521 tcgctcaaac aggtcactgg tgtcggggta aaacccgaca ccagattgtg ctaactccga
     8581 cgggagcaaa tccgtgaaag atttattaaa gtttctgaaa gcgcagacta aaaccgaaga
     8641 gtttgatgcg atcaaaattg ctctggcttc gccagacatg atccgttcat ggtctttcgg
     8701 tgaagttaaa aagccggaaa ccatcaacta ccgtacgttc aaacctgagc gtgacggcct
     8761 tttctgcgcc cgtatctttg ggccggtaaa agactacgag tgcctgtgcg gtaagtacaa
     8821 gcgcctgaaa caccgtggtg ttatttgtga gaagtgcggc gttgaagtga cccagaccaa
     8881 agtacgccgt gagcgtatgg gccacatcga gctggcgtct ccgactgctc acatctggtt
     8941 cctgaaatcg ctgccgtccc gtatcggtct gctgctcgat atgccgttgc gtgatatcga
     9001 acgcgtactg tacttcgaat cttatgtggt tatcgaaggc ggtatgacca acctggaacg
     9061 tcaacagatc ctgactgaag agcagtatct ggacgcgctg gaagagttcg gtgacgaatt
     9121 cgacgcgaag atgggtgcgg aagctatcca ggccctgctg aagagcatgg atctggagca
     9181 agagtgtgaa actctgcgcg aagagctgaa cgaaaccaac tccgaaacta agcgtaaaaa
     9241 gctgaccaag cgtatcaaac tgctggaagc cttcgtacag tctggcaaca agccagagtg
     9301 gatgatcctg accgttctgc cggttctgcc gccagatctg cgtccgctgg ttccgctgga
     9361 tggtggtcgt ttcgccacgt cagatctgaa cgatctgtat cgtcgcgtga tcaaccgtaa
     9421 caaccgtctg aaacgtctgc tggatctggc tgcgccggac atcatcgtac gcaacgaaaa
     9481 acgtatgctg caggaagcgg tcgacgccct gctggataac ggtcgtcgcg gtcgtgcgat
     9541 caccggttct aacaaacgtc ctctgaaatc tttggccgac atgatcaaag gtaagcaggg
     9601 tcgtttccgt cagaacctgc tcggtaagcg tgttgactac tccggtcgtt ctgtaatcac
     9661 cgtaggtcca tacctgcgtc tgcatcagtg cggtctgccg aagaaaatgg cgctggagct
     9721 gttcaaaccg ttcatctacg gcaaactgga actgcgagga ctcgccacca ctatcaaagc
     9781 cgcgaagaaa atggttgagc gcgaagaagc tgtcgtttgg gatatcctgg acgaagtgat
     9841 ccgcgaacac ccggtactgc tgaaccgtgc accaacactg caccgtttgg gtatccaggc
     9901 atttgaaccg gtactgatcg aaggtaaagc tatccagctg cacccgctgg tttgtgcggc
     9961 atataacgcc gacttcgatg gtgaccagat ggctgttcac gtaccgctga cgctggaagc
    10021 ccagctcgaa gcgcgtgcgc tgatgatgtc taccaacaac atcctgtctc cggcgaacgg
    10081 cgaacctatc atcgttccgt ctcaggacgt ggtattgggt ctgtactaca tgacccgtga
    10141 ctgtgttaac gccaaaggcg aaggcatggt gctgactggc ccgaaagaag ctgagcgtat
    10201 ctatcgcgca ggtctggcct ctctgcatgc gcgcgttaaa gtgcgtatca ctgaatatga
    10261 aaaagatgaa aacggcgaat tcgttgcgca caccagcctg aaagacacga ccgttggtcg
    10321 cgccattctg tggatgatcg taccgaaagg tctgcctttc tccatcgtca accaggcgct
    10381 gggcaagaaa gcgatctcca aaatgctgaa cacttgctac cgtattctgg gcctgaaacc
    10441 gaccgttatt tttgcggacc agacgatgta caccggcttt gcttatgcag cgcgttcagg
    10501 tgcgtccgtt ggtattgatg acatggtcat cccggagaaa aaacacgaga tcatctctga
    10561 agcggaagcc gaagttgctg agatccagga gcagttccag tctggtctgg taaccgctgg
    10621 cgaacgctat aacaaagtta tcgatatctg ggctgcggcg aacgatcgtg tatccaaagc
    10681 gatgatggat aacctgcaaa ccgaaaccgt gattaaccgt gacggccagg aagagcagca
    10741 ggtttccttc aacagcatct acatgatggc cgactccggt gcgcgtggtt ctgcggcaca
    10801 gattcgtcag ctggcaggta tgcgtggtct gatggcgaag ccagatggct ccatcatcga
    10861 aacgccaatc accgcgaact tccgtgaagg tctgaacgta ctccagtact tcatctccac
    10921 gcacggtgcg cgtaaaggtc tggcggatac cgcactgaaa accgcgaact ccggttatct
    10981 gacccgtcgt ctggttgacg tcgcgcagga tctggtggtg accgaagatg actgtggtac
    11041 gcacgaaggt atcctgatga ccccggttat cgagggtggc gacgtgaaag agccgctgcg
    11101 tgaccgcgtt ctgggtcgtg tgacggcgga agatgtgctg aagccgggta cggcggacat
    11161 tctggttcca cgcaacacgc tgctgcacga acagtggtgt gacctgctgg aagcaaactc
    11221 cgttgacgcc gttaaagtgc gttccgttgt atcctgcgat accgattttg gtgtatgtgc
    11281 gcactgctat ggtcgtgacc tggcgcgtgg ccacatcatc aacaaaggtg aagctatcgg
    11341 cgttatcgcg gcacagtcca tcggtgaacc gggtacacag ctgacgatgc gtacgttcca
    11401 catcggtggt gcggcatcgc gtgcggctgc tgaatccagc atccaggtta agaacaaagg
    11461 tagcatcaag ctcagcaacg tgaagtcggt tgtgaactcc agcggtaaac tggttatcac
    11521 ttcccgtaac accgaactga agctgatcga cgaattcggt cgtaccaaag agagctataa
    11581 agtgccttat ggcgcagtca tggcgaaagg tgatggcgag caggttgccg gcggcgaaac
    11641 cgtggcaaac tgggacccgc acaccatgcc ggttatcacc gaagtgagtg gtttcatccg
    11701 cttcactgac atgatcgacg gtcagaccat tacgcgtcag accgacgaac tgaccggttt
    11761 gtcttcgctg gtggttctgg attcggctga acgtactacc ggtggtaaag atctgcgtcc
    11821 ggcgctgaaa atcgttgatg ctcagggtaa tgacgttctg atcccgggta ccgatatgcc
    11881 tgcgcagtac ttcctgccgg gtaaagcgat tgtacagctg gaagatggcg tacagatcag
    11941 ttctggtgac accctggcgc gtattccgca ggaatccggc ggtaccaagg atatcaccgg
    12001 tggtctgccg cgcgttgccg atctgttcga agcgcgtcgt ccgaaagagc cggccattct
    12061 ggcggaaatc gcaggtatcg tttccttcgg taaagaaacc aaaggcaaac gtcgcctagt
    12121 gattacgccg gttgatggta gtgacccgta cgaagagatg attccgaaat ggcgtcagct
    12181 caacgtgttc gaaggggaac gtgtagaacg tggtgatgtg atttccgatg gtccggaagc
    12241 gccgcacgac attctgcgtc tgcgtggcgt tcatgctgtg acgcgttata ttgttaacga
    12301 agttcaggat gtataccgtc tgcagggcgt taagattaac gataaacaca tcgaagttat
    12361 cgttcgtcag atgctgcgta aagcgaccat cgaaagcgcc ggtagttccg acttcctgga
    12421 aggcgaacag gttgaatact ctcgcgtcaa gatcgctaac cgcgagctgg aagcgaacgg
    12481 caaagtgggg gctaccttct cccgcgatct gctgggtatt accaaagcgt ctctggcaac
    12541 cgagtcgttc atctctgccg catcgttcca ggagaccacg cgtgtcctga ccgaagcagc
    12601 cgttgcgggt aaacgcgacg aactgcgcgg cctgaaagag aacgttatcg tgggtcgtct
    12661 gattccggcc ggtaccggtt atgcgtacca ccaggatcgt atgcgccgtc gcgccgcggg
    12721 cgagcagcca gcaacaccgc aggtcactgc ggaagatgca tctgcaagcc tggcagagct
    12781 gctgaacgca ggtctgggcg gttctgataa cgagtaatcg ttaaatggtg gaggggtatt
    12841 tatccctcca ccagcttcat gctggatacc gaattccggg tcgcttgcct acaaggaaag
    12901 aaaatgccag cgattatt
//
LOCUS       DAJVBX010000134        12689 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.134, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000134 DAJVBX010000000
VERSION     DAJVBX010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 12689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12689
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.134"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            173..346
                     /locus_tag="OPV72_003137"
     CDS             173..346
                     /locus_tag="OPV72_003137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311393.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2633 family protein"
                     /protein_id="HCR9915361.1"
                     /translation="MRKRHRFNTRMTRIVLLISFLFFFGRFVYSSIGAWQHHQDKKEA
                     QQSSLSVTTPGQR"
     gene            610..1104
                     /locus_tag="OPV72_003138"
     CDS             610..1104
                     /locus_tag="OPV72_003138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311394.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine zipper 2TM domain-containing protein"
                     /protein_id="HCR9915362.1"
                     /translation="MPLVLFASFSLAGCQSNADDYAADVYQTGQLNAKQETKTVNIIS
                     VLPAKVAVDNTANKKTAQTFGAILGAVAGGVTGHNVGSGSGLGTTAGAVGGGAVGAAA
                     GSLVKDKTLVEAVSLTYKEGTKVYTSTQVGKTCQFTTGLAMVISTKDNETRIQPNTKC
                     PEKS"
     gene            1120..1659
                     /locus_tag="OPV72_003139"
     CDS             1120..1659
                     /locus_tag="OPV72_003139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016505922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5384 family protein"
                     /protein_id="HCR9915363.1"
                     /translation="MKKVILGAVLFTLSGSVLSSSLQDQLAAVAQAEQQGKNEENRQR
                     DALQAKRDQEAQQERQRQANAAAVAKQRAKAAEAERKARQAKLAAEAAQDKARDQSYE
                     DELRRLEIQKQKLALAREEARVKRENEFIDQELKSKAAQTDVIQSHADANRNLSEGGR
                     DLLQSEGKAREEKASGWFN"
     gene            1888..2577
                     /locus_tag="OPV72_003140"
     CDS             1888..2577
                     /locus_tag="OPV72_003140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001764183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915364.1"
                     /translation="MKDFSKYSKALGMAKFYVYAFYDTEDAAKKPFYIGKGKSERCLD
                     HIKYNDDSPKSERINHLLKTGNLGIDILRHGMDEATAKLVEATCIDLLGVGELTNKVR
                     GSSSLMGRITLDELNHLLLKQETEIAPEHAGLAFLLNSTYKSGMSALALYEATRGVWA
                     KVPKDENLQFAYATYGGLVMEVYEIQCWLKAGSQQYFTRELVIPPPKPTVQNLLDESH
                     HQKSEDYTLAS"
     gene            complement(2900..4477)
                     /gene="guaA"
                     /locus_tag="OPV72_003141"
     CDS             complement(2900..4477)
                     /gene="guaA"
                     /locus_tag="OPV72_003141"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HCR9915365.1"
                     /translation="MTENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEA
                     QIRDFNPSGIILSGGPESTTEENSPRAPQYVFEAGVPVFGVCYGMQTMAMQLGGHVEG
                     SNEREFGYAQVEVLTDSALVRGIEDSLTADGKPLLDVWMSHGDKVTAIPSDFVTVAST
                     ESCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAV
                     ARIREQVGDDKVILGLSGGVDSSVTAMLLHRAIGKNLTCVFVDNGLLRLNEAEQVMDM
                     FGDHFGLNIVHVPAEDRFLSALAGENDPEAKRKIIGRVFVEVFDEEALKLEDVKWLAQ
                     GTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKMGLVEPLKELFKDEVRKIGLELG
                     LPYDMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRKADLYDKVSQAFTV
                     FLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGRVSNRIINEVNGIS
                     RVVYDISGKPPATIEWE"
     gene            complement(4547..6013)
                     /gene="guaB"
                     /locus_tag="OPV72_003142"
     CDS             complement(4547..6013)
                     /gene="guaB"
                     /locus_tag="OPV72_003142"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004151980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HCR9915366.1"
                     /translation="MLRIAKEALTFDDVLLVPAHSTVLPNTADLSTQLTKTIRLNIPM
                     LSAAMDTVTEARLAIALAQEGGIGFIHKNMSIERQAEEVRRVKKHESGVVTDPQTVLP
                     TTTLHEVKALTERNGFAGYPVVTEDNELVGIITGRDVRFVTDLNQPVSVYMTPKERLV
                     TVREGEAREVVLAKMHEKRVEKALVVDDNFHLLGMITVKDFQKAERKPNSCKDEQGRL
                     RVGAAVGAGAGNEERVDALVAAGVDVLLIDSSHGHSEGVLQRIRETRAKYPDLQIIGG
                     NVATGAGARALAEAGCSAVKVGIGPGSICTTRIVTGVGVPQITAVSDAVEALEGTGIP
                     VIADGGIRFSGDIAKAIAAGASAVMVGSMLAGTEESPGEIELYQGRSYKSYRGMGSLG
                     AMSKGSSDRYFQSDNAADKLVPEGIEGRVAYKGRLKEIIHQQMGGLRSCMGLTGCATI
                     DELRTKAEFVRISGAGIQESHVHDVTITKESPNYRLGS"
     gene            6174..7523
                     /gene="xseA"
                     /locus_tag="OPV72_003143"
     CDS             6174..7523
                     /gene="xseA"
                     /locus_tag="OPV72_003143"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HCR9915367.1"
                     /translation="MLSSQTSSIFTVSRLNQTVRLLLEQEMGQVWISGEISNFTQPAS
                     GHWYFTLKDDTAQVRCAMFRNSNRRVTFRPQHGQQVLVRANITLYEPRGDYQIIAESM
                     QPAGEGLLQQKYEQLKAKLHAEGLFDQQHKQPLPSPAHCVGVITSKTGAALHDILHVL
                     KRRDPSLPVIIYPTAVQGDDAPGQIVRAIELANTRGECDVLIVGRGGGSLEDLWSFND
                     ERVARAIFASRIPVVSAVGHETDVTIADFVADLRAPTPSAAAEIVSRNQQELLRQIQS
                     AQQRLGMAMDYYLANRSRRFTQIFHRLQQQHPQLRLARQQTALERLRQRMGFALEARI
                     KQATQRQQRVSQRLSQQNPQPRIHRVQSRIQQLEYRLTENIRSRLSEQRERFGNAVTH
                     LEAVSPLATLARGYTVSTTTDGKVLKKIKQVKAGDIMTTRLEDGWLESEVKSVTPGT"
     gene            complement(7685..12641)
                     /locus_tag="OPV72_003144"
                     /pseudo
     CDS             complement(7685..12641)
                     /locus_tag="OPV72_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010835061.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
BASE COUNT         2881 a         3482 c         3337 g         2989 t
ORIGIN      
        1 cgcaatttta cattaagagg aattgaccat cggttcgcag tatgccttaa tgtagagtga
       61 acgcaggctt gttacgttct tcgccttgat aatacctttg aagaacccag cctgatcccg
      121 cccataccgc tgggccaacg ttaaggaacc ctttgtaagt caggccaaca gtatgcgaaa
      181 acgacatcga tttaacactc gcatgacccg tatcgtactg cttatcagtt ttctcttctt
      241 ctttggacgt ttcgtctact cttctatcgg cgcctggcag caccatcagg ataaaaaaga
      301 agcgcaacag tcatcgcttt cggtcaccac gccgggacaa cgttaagctg ttatccgtta
      361 aaatagtgat ggcggtatta tcgtcacagg tttgccgtgt tatccagcgc tctgttatcc
      421 ccttccctgg cttagcatga accgataaaa acaaagcatc gtatcatcta atgctttgtt
      481 ttttagtcta aaaaaaacaa tcaactacaa gaaacgatag tttacttttt ttaagattag
      541 tcttaaatac attccttttt gcgttattac ctaaacaagg aattgtgatg aatttaaaaa
      601 aaaaatgctt tgcctctggt tttatttgcc tctttttctc ttgccggatg ccagtccaat
      661 gcggatgact acgccgcaga tgtttaccaa accgggcagt taaacgcgaa gcaagaaaca
      721 aagaccgtca atattatctc tgttttgcca gcgaaagttg ccgtagataa caccgccaat
      781 aaaaaaaccg ctcagacctt cggcgcaatt cttggggctg tagcgggcgg cgttactggt
      841 cataacgtgg gctcaggtag cggtttgggt actactgccg gcgcggttgg cggcggagcc
      901 gttggcgcag cggcggggtc attggttaaa gataaaacgt tagttgaagc cgtatctttg
      961 acttacaaag aaggaacgaa ggtttatacc tccacccagg tgggaaaaac gtgccaattt
     1021 accaccggtc tggctatggt gatatcgacc aaagataacg aaacgcgaat tcaacccaat
     1081 acgaaatgtc ctgagaaaag ctaactatcg ggagatttta tgaagaaagt tattttaggc
     1141 gctgttttat tcactctaag cggctcggtt ttatcttctt ctttgcagga tcagcttgcg
     1201 gcggtagccc aggctgaaca gcaaggaaaa aatgaagaaa acagacagcg tgatgctctg
     1261 caagccaaac gagatcaaga ggctcaacag gaaagacaaa ggcaagccaa tgcggcagcg
     1321 gttgctaagc agcgagcaaa agcggcagaa gctgaacgga aagcacggca agcaaaattg
     1381 gcagcggaag ccgcgcaaga taaagcgcgc gatcaaagct acgaagatga gcttcgtcgt
     1441 ttagaaattc agaaacaaaa actggcgctg gccagggaag aggcccgggt aaaaagagaa
     1501 aatgaattca tcgatcaaga gctgaaaagt aaagctgccc agacagatgt tattcaatct
     1561 catgctgatg caaacagaaa tctatctgaa ggcggtcgcg atctgctgca aagcgaaggt
     1621 aaagcccgtg aggaaaaggc aagcggctgg tttaactgat ttcgctaatc atttatgtgt
     1681 attagctcag atttgacctg acatagctat ggcacagacc taaacctaat ctgacaggca
     1741 ggtctgtgcc aatagcggac gttgttaact ttggcccata ttcatcaatg gacgcaggtc
     1801 aatctatacg ctaattgttt tgcgcttaag ttctgaacta tagtgccgat agtaaaatta
     1861 agtacttttg ccttaaggaa gcaaggtttg aaagattttt caaaatactc aaaagcgtta
     1921 gggatggcta agttctatgt ttatgcattt tatgacactg aagatgcagc taagaagccg
     1981 ttttatatag gcaaaggcaa gtcagaacgc tgccttgatc atataaagta taatgatgac
     2041 tctccgaaat cagaacgaat taatcatctg ttaaaaacag gaaatctggg tatcgacata
     2101 ctacgccatg gcatggatga ggcaaccgcg aagcttgttg aagcaacatg tattgatctc
     2161 ttgggtgttg gagaactgac caacaaagta cgaggaagca gctcccttat ggggcgaatc
     2221 acgctggatg agctcaatca tcttcttctt aagcaagaga cggaaatcgc acctgaacat
     2281 gccgggctcg cttttttgct aaacagcacc tacaagtctg gcatgagtgc acttgcatta
     2341 tatgaagcta cgcgtggcgt ctgggcaaaa gtaccaaaag atgaaaacct acaatttgca
     2401 tacgccacct acggcggttt ggtgatggaa gtttacgaga tacagtgctg gttgaaggca
     2461 ggctctcagc aatactttac ccgggaattg gtcatccccc ccccgaaacc aaccgttcag
     2521 aatttgttgg acgaatcgca tcaccagaaa tcagaggatt atacgttggc aagctaatca
     2581 aaaaatcgcg tagtcatggt agccctttcg taaaagtcgg gctggcggag taaactgacc
     2641 tgcttcccgt tgattaatac acctcaatgc cagtcatgtt gttgaagcta ccaatgtccg
     2701 cacctcgctc gaagccgact gtcagatttg attgtgtgct gccagtgaaa cccactattg
     2761 tgtcgatgca gtgctttgcc gccagaagct gtgcactaca cagaaaatgc atctatgcac
     2821 ataaataaaa accctctgca aaaacagagg gttaaattca cttttacctg ttcatgaaaa
     2881 cacaggaagg gttatcgact tattcccact caatggtagc cggtggttta ccgctgatgt
     2941 catacaccac acgggaaatc ccgttgactt cattgatgat gcggttggaa acacgaccca
     3001 ggaagtcata cggcaggtgc gcccagtgcg cggtcataaa gtcgatggtt tcgacagcac
     3061 gcagagagac cacccaatcg tacttacgac catcgcccat tacgccaacg gagcgtactg
     3121 gcaggaagac ggtgaacgcc tggctgactt tgtcgtacag atccgcctta cgcagctctt
     3181 caatgaagat ggcatcagca cggcgcagca ggtcgcagta ctctttcttc acttcaccca
     3241 gtacacgtac gccgaggccc ggccccggga acggatgacg gtacagcatg tcgtacggca
     3301 ggcccagctc cagaccaatc ttacgcactt cgtctttgaa cagctctttc agcggttcaa
     3361 ccagccccat cttcatctct ttcggcaggc cgccaacatt gtggtgagat ttgatgacgt
     3421 gcgctttacc ggttgcagac gccgcagatt cgatgacgtc agggtagatg gtgccctgcg
     3481 ccagccattt cacgtcttcc agtttcaacg cttcttcgtc gaacacttcc acaaaaacac
     3541 ggccaatgat cttacgcttc gcttccggat cgttttcgcc agccaacgcg gacaggaagc
     3601 gatcttctgc cggtacgtga acgatgttca gaccaaaatg gtcgccaaac atgtccatca
     3661 cctgctcggc ttcgttgaga cgcagcaggc cgttgtcgac gaatacacag gtcagatttt
     3721 taccgatcgc gcggtgcagc agcattgcgg ttacggaaga atccacgccg ccggagagac
     3781 cgaggatcac tttatcgtcg cctacctgct cgcgaatgcg cgccacggcg tcgtcgatga
     3841 tcttcgccgg cgtccacagg gcttcacact ggcagatatc acgcacaaaa cgctccagca
     3901 tgcgcatacc ctggcgggtg tgagtcactt ccgggtggaa ctgtacgccg tagaagcgtt
     3961 tttcttcgtt agccatgatg gcgaacgggc agctttcggt gctggctacg gtcacgaagt
     4021 cggacggaat cgccgtcact ttatcgccgt ggctcatcca cacgtccagc agcggtttgc
     4081 cgtcggcggt cagggaatct tcaataccgc gaaccagcgc gctgtcggtc agcacttcga
     4141 cctgcgcgta accaaattca cgctcattag aaccttctac atgaccgcca agctgcatcg
     4201 ccatggtctg catcccgtag cagacgccaa ataccggcac gcctgcttca aagacatact
     4261 gcggcgcgcg cgggctgttt tcttcggtgg tgctttccgg gccgccggaa agaataatgc
     4321 cgcttgggtt gaagtcacga atttgtgctt ctgtcacatc ccacgcccac agttcgcagt
     4381 aaacacccag ctcacgcacg cggcgcgcaa ccagttgagt gtactgagaa ccgaagtcca
     4441 gaatgaggat gcgatgctta tgaatgtttt ccgtcattga cgcttattcc gaggcaagtg
     4501 aaacagatta aataaatcgc ccgacgcgaa ggtcgggcga agaaaatcag gagcccagac
     4561 ggtagttcgg ggactctttg gtgatggtca cgtcgtgaac gtggctttcc tggatacccg
     4621 caccgctgat acgcacaaac tccgctttag tacgcagttc gtcgatggta gcacaaccgg
     4681 tcagccccat acaggagcgc aggccgccca tctgctggtg aatgatctct ttcaggcgac
     4741 ctttataggc tacgcggcct tcgatacctt ccggcaccag tttgtcggcg gcgttgtcgc
     4801 tctggaagta acggtcagag gaacctttgg acatcgcgcc cagcgagccc atgccgcggt
     4861 aagatttgta agaacggccc tggtagagtt cgatttcgcc cggggattct tcggtacccg
     4921 ccagcataga accgaccatg acagcgctcg cgcctgcggc gatggctttg gcgatgtcgc
     4981 cggagaaacg gataccgccg tcagcgataa ccggaatccc ggtgccttcc agcgcttcaa
     5041 ctgcgtcaga aacagcggta atctgcggaa cgcccacgcc agtcacgata cgagtggtac
     5101 agatggaacc cgggccgata ccgactttca ccgcgctgca accggcttcc gccagtgcgc
     5161 gagcgcctgc gcccgtcgcg acgttgccgc cgatgatttg caggtcagga tatttagcac
     5221 gggtttcacg gatacgttgc aacacgcctt cagagtgacc gtgagaagag tcgatcagca
     5281 ggacgtcaac gcctgccgcc accagcgcgt caacgcgctc ttcgttgccc gcgcctgcgc
     5341 cgaccgccgc gccgacacgt aaacggccct gctcatcttt acaggagttt ggtttacgtt
     5401 ccgctttctg gaaatctttt acggtaatca tgccaagcag atggaagtta tcatcaacga
     5461 ccagcgcttt ttctacgcgt ttttcgtgca tttttgccag cacgacttca cgggcttcgc
     5521 cttcacgaac ggtcaccaga cgctctttcg gcgtcatgta aacactcacc ggctggttca
     5581 ggtcagtcac aaaacgcacg tcacgaccgg tgatgatacc caccagctcg ttatcttcag
     5641 tcaccaccgg atagcccgca aaaccgttac gctcggtcag ggctttcact tcatgcaacg
     5701 tggtggttgg caggacggtc tgcgggtcgg tcactacgcc ggactcgtgt ttcttcacgc
     5761 ggcgaacttc ttccgcctgg cgctcaatag acatgttttt gtggataaaa ccgatgccgc
     5821 cttcctgggc cagggcaatt gccaggcgcg cttccgtcac ggtgtccatc gccgcagaaa
     5881 gcataggaat attcagacga atagttttcg tcaactgcgt gctgagatca gcagtattcg
     5941 gcaaaacggt ggagtgagcg ggaacaagga ggacgtcgtc aaacgtcagg gcttctttag
     6001 cgatacgtag catgggcaat atctcacctg ggaggttaat aaatattgcc gcggcattat
     6061 acagaacgta atcggttgca tctacatttt tttgcaaata gtgcttgcga tcccccgtga
     6121 gcaggttact atcgattgaa taacctgctg atttagaatt tgatcccgct cacatgttat
     6181 cctctcaaac ttcctcaatt tttaccgtaa gccgccttaa ccagacggtt cgtctgctgt
     6241 tagaacagga gatgggacag gtatggatca gcggcgagat ttctaatttc acgcagcctg
     6301 cgtcgggcca ctggtacttt acgctcaaag acgataccgc tcaggtgcgc tgtgcgatgt
     6361 tccgcaacag caaccgccgg gtgacgttcc gcccgcagca cgggcagcag gtgctggtac
     6421 gcgccaacat tacgctgtac gagccgcgcg gcgattatca aatcatcgcc gaaagtatgc
     6481 agccggctgg cgaaggcttg ttgcagcaga agtatgagca gctaaaagcc aaactccatg
     6541 ccgaaggctt gttcgatcag cagcataaac agccgttgcc ctccccggcc cactgcgttg
     6601 gggtgatcac ctcgaaaacc ggcgcggcgc tgcacgatat cctccacgtg ttgaagcgtc
     6661 gtgacccatc cctgcccgtt attatctatc caaccgcggt acagggcgac gatgcgccgg
     6721 ggcagatcgt tcgtgctatc gaactggcaa acacgcgcgg cgagtgcgac gtgctgatcg
     6781 tcggacgcgg cggcggttcg ctggaagatt tgtggagttt taacgacgaa cgcgtggcgc
     6841 gggctatttt tgccagccgt attccggtgg tcagcgccgt cggtcacgaa accgacgtca
     6901 ctatcgccga ttttgtcgcc gacctgcgcg cgccgacgcc atcagcagcg gcagaaattg
     6961 tcagccgtaa ccagcaggag ttgttgcgtc agatccagtc cgcccagcag cgtctgggca
     7021 tggcgatgga ctactacctc gccaaccgca gccgtcgttt cacgcagatt tttcaccgtc
     7081 tgcaacaaca acatccgcaa ctacgtctgg cccgtcagca aaccgcgctg gaacgtctac
     7141 gccaacggat gggatttgcg cttgaggcca ggattaagca ggccactcag cgtcagcaac
     7201 gcgtaagtca acgcctgagc cagcaaaatc cgcagccgcg cattcaccgc gtgcagtcgc
     7261 gcatccaaca gctggaatat cgtctgacgg agaatatccg ctcacggtta agcgaacagc
     7321 gcgagcgttt tggcaacgcg gtcacgcatc tggaagcggt cagcccgtta gccacgctgg
     7381 cgcgcggcta tacggtttcg acgacaacgg acggcaaggt gttgaaaaag atcaaacagg
     7441 tcaaagcagg cgatatcatg accacgcggc tggaggacgg ctggcttgaa agtgaagtca
     7501 aatccgtcac gccgggaacg taatccaaca ctcccccacc ttttgcagcg cgatgttggg
     7561 tttcgacttc acctcagcca acccacgcgc cacgtcggat aaggtgtagc cacaatccga
     7621 cgctcaaccg gtttgtcatt cgcctcaaaa ccgggcaggg aatacccgcc cggttttgtc
     7681 taacttacca gttatagcgc agattgaggc taccgttcag atcgccaaag tcattgctgc
     7741 cagtctgccc ggcaacctga gcgcgaacgc tccactgctt atcgatatct gcctgcagac
     7801 ccactttcag ctccgcacgg ttagccggaa gatcctgttt caccgtggca tcatcaaacg
     7861 ataccgacac atcatcgctg gtgtgcagcc agttggcttc agcaaacggc tggataaccg
     7921 tacggctgcc tttgtacagc ttgccgtcaa cacgcagacc caggcgcgtt gtccaactgt
     7981 cgccatcctg accgtcgatc cgggtgccgt agttatcctt cacgctatcc gctgagtagt
     8041 tctgccagac aacctgcgcc tgcggcgtca gactgacagt attaccgttg ctaagcgcaa
     8101 tatcgtagcg ataaccggtt tccagcgaga cagcattagc ggttgaatca taagattcag
     8161 atcccgcatc accgctctct acgctgttgt tgtagaaacc atattggtac cagctgtcga
     8221 catacgcgcc gctatgcgtt tgggcatcgg caaaccaggt ggcatagacg ccaaggttgt
     8281 agccgtctac gttggcgctg ctggtgaact ggctaccgtc tgcgccacgg ttaccggtgc
     8341 tgtcggtatc ggcgttgatg tagctcgcta tgacgccaac ggtaatgctc tgttggccgt
     8401 taccccaagc cagaatgtcg ccgcctagct ggaactgaga gtagttgctg tccatatcga
     8461 tattaccgct gacagcctct gattccgctt tacccgcttt gaagcgtgcc cagacgctgc
     8521 catcagcgtt acgatactgg ctgccctcgc ggtcatagag ggtctgtctg catttgcagg
     8581 ttgcgcgcca tccactggtt gcccatgtac gcgccgatat ccgcacggta ctgtggtgcg
     8641 acatcgccgc cgtcgtccgg aggcgtgaca tcgccaccgt cgccgccgtc gtccgaaggc
     8701 gtgacatcgc caccgctgtc gtcatcatca gactgtgctt ttgacgccag ataccagtcg
     8761 ttgtcacttt cattccagta cagacggtag gtatacagac tggcgtttac ctcatttttt
     8821 aacacaaacg catcgctggt cgatacgccg ccaacatcca ccacttcgat accgttagtg
     8881 gtctgcgccc catcgccgat gccgttgatg tacagatcgg tggtgccgga ggcatcgccg
     8941 gtaatgacca acttatcggt cgccgaatca tcgtcgccca ggacggtatt caggtaaagc
     9001 gagccgccgt tgccggtttt atcgcccagt acgctggtga cttcaaagct atcgcctgcg
     9061 cccagagtga aggtgccgtg tgctggcgtc gctgacgtgg cggtcgcatt ccagctcagc
     9121 ccttcggtaa gcaggtattc agactggtct tgaggattga ttgttccggt tacggtcaga
     9181 tagtccggct tgtcggtgag gttcatcgtc aggctggtaa agtcgccgct gatatcgctg
     9241 tccatatcca tcagtttaaa ggactggaac tccgcgtcgg aggcgcgcgc ttgtaggctg
     9301 gcgtcgctga cgaccaaatc accgccaagc gtggcgctgc caccggtaat cagcggttgc
     9361 gctgagtcac tattcagctc aacgttcagc gtactgccat cttcctgaat taacgcgctg
     9421 tcgccgagat ccaacgaggt gccgagcgcc agttgggtcg tcgcgccgcc atgagtggtg
     9481 atgccgccca ccgcgctgac ttcaccgtct gcgtccagta ccagcgtggc gttattgtcc
     9541 accagaccgg tgcccagcgc cgtcgtgctg gcggcgacca gcgtaccttc attgattgta
     9601 gtgccgccgc tgtagtcgtt gtcgccggag aggatcagcg tgcctgcgcc ttctttggtc
     9661 agcgacttac cgtcccatgt gctgcccgga tccagcgcgt catcaacatc tgtcagttta
     9721 gccgcaacgt taaagctgcc gtcagggtca cttagcgtaa aggtgccgtg ggcgtcggta
     9781 gaagcgttgt ctctgtccgc ataccaggag agggaggccg tcagatcata gtttgtgcta
     9841 tctgcttcgt cgacttttcc gtcgatggtc aggaagtcaa catcttcgct attcattccc
     9901 gcgacggtca aatcattgaa atcggtcgta atggcgctgt cgctgtcaat cagcgtgtag
     9961 gtgtatgcct caggcgtcca gctgtctgtg acgttgccga tcccggtaat gttgagcgca
    10021 ccagccaacg agacgctgtc agcggtaatg gcgctttcac cattagtctt actgaggtca
    10081 atattcagcg tactatcggc ttgctgagtc agcgagtcga cgttgagcgt cgtacctttg
    10141 gacagctcag tcgttgctcc agactgggtc gtgacattcg caaggttgaa ttcgccctcc
    10201 gcgtccagct tcagcgtact cgcgttatcg acatcaccgc cgcccagcgc gttaacgttg
    10261 gcggcaatca gcgtaccgcc ggaaatagtg gtgccgccgg agtaagtgtt gtcgccgctt
    10321 aacgtcagct cgcccgtacc ggttttcatc agcgaaccgt tgccggaaag cgtattttcc
    10381 agctcgcctt cgccgacctg aagcacgccg ctgttggcaa cagccccggt acccagcgaa
    10441 tctgcatggt cagcaatcag cgtgccgtcg gaaatagtgg taccgccgct gtagttgtta
    10501 tcgccggtca cgatcagctc atcgctaccg cttttgacaa tttggccctc gccggtcacg
    10561 ttgttatcca gcgtgccttg gctcaactca agctttgcgt tttctgcaat ggccacgtcg
    10621 ccgctgccga gcgcggcggc atcattcgca gacagcgtac cgccgttaat gtcggtattg
    10681 ccgaagtcgt tcgccgtgtt gctgaggacg agcgtaccgt cgccttcttt gaacagcgtt
    10741 ttaccgtccc agttggaggt ggccgcggtt tcatccagtt cgctggtgac ggtaaaggta
    10801 tcgcctgcgt caacggtaaa ggtgccgtgc gcaacgcgcg cagattttgc gtccgcgtac
    10861 cagctcaggc ccgtagacaa cacgtagttg gtattatcat tcgcatcaac gcccgcgttg
    10921 atcgtcaggt aatccggcat agcagaggtg tcggcatcca gcgttacgct gtcaaaatcg
    10981 gtagtaatcg cggtttgcga atcaattagc gtgaacgatc ctaactgctc gtcggtttcg
    11041 ggcgcgacaa aggtggccgc tgagctaagg ttcagtgtcc catccagcgt cacgttggcg
    11101 gctttgataa ttggcgagct gttggcggta tccagcgtcg cgtttatctg gctgccgtcc
    11161 tgcaaggtca gggtattgcc caccgtcagc agcgtgcctg tcgaaccgct ctcgttgttc
    11221 agcgtaatgt cgccgttgtt ggtcaggttg ccgatgattg acgagtcggt catattccac
    11281 tggctagtat cgtcgagcga cagtgtagta aacatcgcat ctacactacc ggttaacgtg
    11341 gaaccctggc ttaaagacag cgatgacgat gacatgtcac tctgaacaac gtcaccgttc
    11401 aatgtcgtat tgtcggcctg aatgaccgcc ttgctgccca gcttgatcac tgccggcgcg
    11461 tcaaatgcgc tatcggttag cacgatagga tcgttaatcg tcgtgccaga gtccacatgc
    11521 agcgcaatcg tctctgaatt aacctgtgct ttgttaaccg tcagcgcgtt gatatcatca
    11581 tacccaccgc ttttaccttt gcttgttata aagatgccgt cgccgtcggc gttgatggtg
    11641 gcgccgttaa tatccacgct ggaggcgagg attttaatac cgatgccttt ggagttgatg
    11701 gccatcgaat ctttatcatc agagatgctc accgttgagg cgtttttcac ctcaatagcg
    11761 gcgcctgtgg cattatcgtg cgtgacggta gagttcgtaa tatcaagaac gcccttgttg
    11821 gacacaagaa gcgtactatc cgtacccgtg gagctcatcg tgctatcgga cacattcagc
    11881 caggagttgt atgtcgtctc gcctactacg cgcacctggc cgtttgtcag cgtaattacg
    11941 ctcccgtcct taatgttaag cgtgctacct gattgtgaca ctatgctgct acggctttgc
    12001 gtcgttgccg taacgtcggt gccaatcagg gcagcccatg actcgccaga gagggtcagg
    12061 atgccgtaat tacttccgat ctggatgctc ccgccattca gcgtcatgct gctttgcgcc
    12121 tggaggtcga tacctgccgt gtaggttcct tccgtagaga tctgcgcccc ggtcaggtca
    12181 agtgttgcgc ccttgttgag ggtaactgcc gtggcgatag catgagttcc ctgaacagga
    12241 tcgccgccgc cgttggtgtt aatcacgaca tttgtacctg tacccgacgt tgcctgccag
    12301 cccccttcgg gcgttgcaag gccttcgagg tgcagtgcag aaccttcacc agtgcctgag
    12361 taggaaatcg gcgaatcgtc gctcaggtcg tgcttgaccc catcggtgta tgacaccgga
    12421 ttatcggcga tggccagcgg gctggcaaag ccaagcgcgg caacaattgc cagggccagc
    12481 gcatggtgtc ttgcccatcc tgaatcaggc tttttaatag aaggggcgac ttcattagcg
    12541 tgcgcctgta ttttaacttt gctgtggctt cgcgccagtt ctgaagctac gacatacata
    12601 tttcgcacgg cgctccagac gatactgtag gtcctgttca atttttaaat ttccttttaa
    12661 taacattcac gaagcaaact tgatttgat
//
LOCUS       DAJVBX010000135        12659 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.135, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000135 DAJVBX010000000
VERSION     DAJVBX010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 12659)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12659)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12659
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.135"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..526
                     /locus_tag="OPV72_003145"
     CDS             <1..526
                     /locus_tag="OPV72_003145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="two component system response regulator"
                     /protein_id="HCR9915368.1"
                     /translation="LEVYNACCAYEPDILILDLSLPGINGLDIIPQLHQRWPAMNILV
                     YTAYQQEYMTIKTLAAGANGYVLKSSSQQVLLAALQTVAVNKRYIDPTLNREAILAEL
                     NADTTNHQLLTLRERQVLKLIDEGYTNHGISEKLHISIKTVETHRMNMMRKLQVHKVT
                     ELLNCARRMRLIEY"
     gene            705..1433
                     /locus_tag="OPV72_003146"
     CDS             705..1433
                     /locus_tag="OPV72_003146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCR9915369.1"
                     /translation="MSYSIGEFARLCGINAATLRAWQRRYGLLKPQRTDGGHRLYSDD
                     DIRQALSILDWVRKGVPISQVKPLLSRPVIRLGDNWITIQETMLQHLHEGRIDALRQL
                     IYDCGREYPRAELVTHLLRPLRSKVSAHLPAVMTLREILDGIIIAYTSFCLEGDRKAP
                     GNNAFISGWHLSDHCEIWLEALTRTGQELRLNVLPSPPAVLAPELFAQRKWFLVTTGK
                     LTAGQKKQLAQWRNVVASLEVITL"
     gene            1605..2564
                     /locus_tag="OPV72_003147"
     CDS             1605..2564
                     /locus_tag="OPV72_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 and DUF1722 domain-containing protein"
                     /protein_id="HCR9915370.1"
                     /translation="MNNKPVVGISGCLTGAAVRFDGGHKRMDFVMNSLAPWVAYKPIC
                     PEVAIGLPVPRPALRLIQTTCGDIRMRYSHAPHDDVTERMNAFADRFLPTIGELAGFI
                     VCAKSPSCGMERVRLYDEKGNRGRKAGTGLFTAAMMDKYPWLPIEEDGRLHDPVLREN
                     FIARIFALHELNALRAQGLSRHSLLAFHSRYKLQLLAHHQAGYREIGPFVARLHEWDD
                     LDAFFVRYREKLMAILRHPASRKNHTNVLMHIQGYFHRALNSRQRAELREVILGYRAG
                     RLPILAPLTLLKHYLAEHPDDYLRSQNYFEPYPDTLGLRLAIT"
     gene            complement(2660..2872)
                     /gene="fumD"
                     /locus_tag="OPV72_003148"
     CDS             complement(2660..2872)
                     /gene="fumD"
                     /locus_tag="OPV72_003148"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase FumD"
                     /protein_id="HCR9915371.1"
                     /translation="MTKPTKDDELYREMCRVVGKVVLEMRDLGQEPKYIVIAGVLRTA
                     LANQRIQRSALEKQAMETVINALARS"
     gene            complement(2970..3590)
                     /gene="ttrR"
                     /locus_tag="OPV72_003149"
     CDS             complement(2970..3590)
                     /gene="ttrR"
                     /locus_tag="OPV72_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460352.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator TtrR"
                     /protein_id="HCR9915372.1"
                     /translation="MATIHLLDDDTAVTNACAFLLESLGYDVKCWTQGADFLAQASLY
                     QAGVVLLDMRMPVLDGQGVHDALRQCGSTLAVVFLTGHGDVPMAVEQMKRGAVDFLQK
                     PVSVKPLQAALERALTVSSAAVARREIILCYQQLTPKERELASLVAKGFMNREIAEAM
                     NIAVRTVEVHRARVMEKMQAGSLAELIRRFEKMASPETRIRTTYEP"
     gene            complement(3565..5343)
                     /gene="ttrS"
                     /locus_tag="OPV72_003150"
     CDS             complement(3565..5343)
                     /gene="ttrS"
                     /locus_tag="OPV72_003150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     TtrS"
                     /protein_id="HCR9915373.1"
                     /translation="MRGKTVRRLAVLAAVGLLCHGAWAGTWNIGILAMRGEASTRSHW
                     QPLAKTLSQQLPGETFHIQPLDLHQMQEAVNQGTVQFVITNPAQFVQLNSHAPLRWLA
                     SLRSTRDGKAVSNVIGSVILTRRDSGITTAHDLIGKTVGAIDAQAFGGYLLGYKALSD
                     AGLRPERDFHLRFTGFPGDALIYMLREKAVQAAIVPVCLLENMDQEGLINKKDFIALL
                     SRPTPLPCLTSTPLYPDWSFAALPAVSDALADRVTRALFNAPAAASFHWGAPASTSQV
                     EALLRDVRQHPQQRRLWLDVKSWLIQHQLMVGGVILAFLLLTLNYIWVMLLVRRRGKQ
                     LERNSVVLHQHERALETARQMSVLGEMTSGFAHELNQPLSAIRHYAQGCLIRLRAADE
                     QHPLLPALEQIDQQAQRGADTLRNLRHWVSQAQGNPVLTEAWKAIAIREAIDHVWQLL
                     RMAQQFPTVTLHTEVSAALRVTLPSVLLEQVLANIILNAAQAGATHLWVVAERTENGI
                     SIVLQDNAGGIDEALLRQAFQPFMTTRKEGMGLGLAICQRLVRYGRGDISIRNQTAPD
                     GLSGTVVTIHFLHEHGGRDGDNSSTG"
     gene            5507..6259
                     /gene="ttrB"
                     /locus_tag="OPV72_003151"
     CDS             5507..6259
                     /gene="ttrB"
                     /locus_tag="OPV72_003151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetrathionate reductase subunit TtrB"
                     /protein_id="HCR9915374.1"
                     /translation="MWTGVNMDSSKRQFLQQLGVLTAGASLVPLAEAKFPFSPERHEG
                     SPRHRYAMLIDLRRCIGCQSCTVSCTIENQTPQGAFRTTVNQYQVQREGSQEVTNVLL
                     PRLCNHCDNPPCVPVCPVQATFQREDGIVVVDNKRCVGCAYCVQACPYDARFINHETQ
                     TADKCTFCVHRLEAGLLPACVESCVGGARIIGDIKDPHSRIATMLHQHRDAIKVLKPE
                     NGTSPHVFYLGLDDAFVTPLMGRAQPALWQEV"
     gene            6260..7282
                     /gene="ttrC"
                     /locus_tag="OPV72_003152"
     CDS             6260..7282
                     /gene="ttrC"
                     /locus_tag="OPV72_003152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetrathionate reductase subunit TtrC"
                     /protein_id="HCR9915375.1"
                     /translation="MTHSLIIEEVLAHPQDISWLPWAVQYFFFIGIAACAALFACYLH
                     WRKKDAATEENRALLIAITCAITAPLALTADLHQTARVWHFYAWPTPWSWMPWGALFL
                     PLFTGFLALWFLAQQIKRLFNKSYNVTKWLALASALCAVGLLIYTGREVSVVLARPIW
                     FSYAFPVAMFLSALQAFFALMIVAARRDSVRLPKILWGQLWTLAALGLVVAMWVSGDT
                     LSGTAIRQWITVALSAKYYAVGWLALWVFTLLFCSLALRHPLSELRRVLLVLSALALC
                     WLMRWTLLIQVQTVPKFNAQFNPYTLPGGTDGWLAILGTFGLWIALLISIRETLNGLT
                     RRLQHG"
     gene            7275..10337
                     /gene="ttrA"
                     /locus_tag="OPV72_003153"
     CDS             7275..10337
                     /gene="ttrA"
                     /locus_tag="OPV72_003153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetrathionate reductase subunit TtrA"
                     /protein_id="HCR9915376.1"
                     /translation="MANLTRRQWLKVGLAVGGMVTFGLSYRDVAKRAIDGLLNGTSGK
                     VTRDRIFGNALIPEAQAQTHWQQNPQQTIAMTQCFGCWTQCGIRARVNADGKVIRIAG
                     NPYHPLSQEHPIDSSVPFSEAMEQLAGESGLDARSTACARGATLLESLYSPLRLLEPM
                     KRVGKRGEGKWQRISFEQLIEEVVEGGDLFGEGHVDGLRAIHAPDTPIDAKHPSFGPK
                     TNQLLVTNTSDEGRDAFLRRFALNSFGSKNFGAHGAYCGLAYRAGSGALMGDLDKNPH
                     VKPDWENVEFALFMGTSPAQSGNPFKRQARQLASARLRENFQYVVVAPALPLSTVLAD
                     PRGRWQPVMPGSDSALAMGMIRWIMDNQRYNADYLAIPGVQAMQQAGEQSWTNATHLV
                     IADELPTLAGQHLTLRHLTPDGEETPVVLNTDGELVDASTCRQARLFVTQYVTLADGQ
                     RVTVKSGLQRLKEAAEKLSLAQYSEQCGVPEAQIIALAETFISHGRKAAVISHGGMMA
                     GNGFYNTWSVMMLNALIGNLSLSGGVFVGGGKFNGVSDGPRYNMNSFAGKVKPSGLSI
                     ARSKTAYKASEEYRDKIAGGQSPYPAKAPWYPFVAGQLTELLTSALEGYPYPLKAWIS
                     NMSNPFYGVPGLRAVAEEKLKDPRRLPLFIAIDAFMNETTALADYIVPDTHNFESWGF
                     TAPWGGVASKATTARWPVVAPATHRTADGQPVSMEAFCIAVAKRLHLPGFGDRAITDP
                     QGNTFPLNRAEDFYLRVAANIAFMGKTPVALANQEDISLTGVSRILPAIQHTLKADEV
                     GRVAFIYSRGGRFAPEDSGYTEQRLGNAWKKPLQIWNADVAAHRHAITGERFSGCPVW
                     YPARLSDGRAIDDQFPIGQWPLKLISFKSNTMSSSTAVIPRLHHVKPANLVALNPQDG
                     ERYGLQHGDRVRIITPGGQVVAQISLLNGVMPGVIAIEHGYGHREMGATQHSLDGVPM
                     PYDPQIRAGINLNDLGFADPTRTITNTWLDWVSGAAVRQGLPAKIERI"
     gene            10660..11878
                     /locus_tag="OPV72_003154"
                     /pseudo
     CDS             10660..11878
                     /locus_tag="OPV72_003154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460347.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
     gene            11890..12627
                     /locus_tag="OPV72_003155"
     CDS             11890..12627
                     /locus_tag="OPV72_003155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HCR9915377.1"
                     /translation="MKILFIGESWHIHMIHSKGFDSFTSSKYEEGADYLLSCLRQGNI
                     DVDYMPAHIVQTRFPQTAEALACYDAIVISDIGSNTFLLQNRTFYNMDIIPDALQLIA
                     DYVAEGGGLLMIGGYLSFTGIEAKANYKNTVLAEVLPVDMLDVDDRVELPQGCKAVNT
                     AVKHVITQPFSEWPPLLGYNKLIAKENSQVLAEINGDPLLVMGTYHKGKVCCFASDCS
                     PHWGSPQFLQWEHYATFWCNVLHTIKK"
BASE COUNT         3008 a         3460 c         3219 g         2972 t
ORIGIN      
        1 tcttgaggtt tataatgcct gttgcgcata cgagcctgac atacttatcc ttgatcttag
       61 cttacctggc atcaatggcc tggatatcat tcctcaatta catcagcgtt ggccagcaat
      121 gaatattctg gtttacacag cataccaaca agagtatatg accattaaaa ctttagccgc
      181 aggtgctaat ggctatgttt taaaaagcag tagtcagcaa gtcctgttag cggcattgca
      241 aacagtcgca gtaaacaagc gttacattga cccgacgttg aatcgggaag ctatcctggc
      301 tgaattaaac gctgacacga ccaatcatca actgcttact ttgcgcgagc gtcaggttct
      361 taaacttatt gacgaggggt ataccaatca tgggatcagc gaaaagctac atatcagtat
      421 aaaaaccgtc gaaacacatc ggatgaatat gatgagaaag ctacaggttc ataaagtgac
      481 agagttactt aactgcgccc gaagaatgag gttaatagag tattaaccag gggcatccga
      541 tggtattaag cattggtcat attttgatga gccttacgcc acgcagtatt gctcatcatc
      601 gacaaaatcc atacggatgc cctggtatgc cgcaccattt atcactacct tagtcttcat
      661 ttaatcatga tatagtagaa tccccttatt taacgggctt taccatgtcg tattctatcg
      721 gcgaatttgc cagactatgc ggtatcaatg ccgccacgct aagggcatgg cagcgacgct
      781 atggtttatt gaaaccgcag cgtactgatg gcgggcatcg cttatacagc gatgacgata
      841 ttcgacaagc gcttagcatc ctcgactggg tgagaaaagg cgtaccgata agtcaggtca
      901 aacccttact gtcgcgtccg gtcattcgcc tgggcgataa ctggataacg attcaggaga
      961 cgatgcttca acatctccac gaagggcgaa ttgacgcgct gcggcagttg atttatgact
     1021 gtggccggga atatccccgc gcagaactgg tgacccattt attgcgtccg ttgcgcagca
     1081 aagtgtccgc gcatcttccc gccgtgatga cgctgcgcga aatattggat ggcatcatta
     1141 ttgcctacac ctctttttgc cttgaaggcg acagaaaagc gcctggcaac aatgctttta
     1201 ttagcggatg gcatctctcg gatcactgtg aaatctggct ggaagcgttg actcgtaccg
     1261 gacaagagct gcggctcaat gtgcttccct ctccaccagc cgttctggcg cccgagctgt
     1321 tcgcccagag aaaatggttc ctggtgacca ccggcaagct cactgccggg cagaaaaaac
     1381 agcttgccca gtggcgcaac gtggtcgctt cgctggaggt tatcacacta taagcgctga
     1441 aatagatttc ttcccctcat tctatcttat tgatatttaa gtacatcaaa aaaatctccg
     1501 cgaaaactta gacaaaaaaa caaagttgtg taagttttaa atcagcgtga gataacattt
     1561 tgcgccgttg gcgtcagtcg tcgtactttc aataaggggg aatcatgaat aacaaacccg
     1621 tagtcggcat tagcggatgt ctgactggcg ccgcggtacg ctttgatggc ggacataagc
     1681 gtatggattt tgtcatgaac tctctggcgc cgtgggtggc ctacaaaccg atctgcccgg
     1741 aggtggcgat cggcctgccc gtgccccgcc ctgcgctgcg tcttatccag acgacctgtg
     1801 gcgacattcg gatgcgctat agccatgccc cgcacgatga cgtcaccgag cgaatgaatg
     1861 cctttgccga tcggtttctg ccaacaatag gcgaactggc ggggtttatt gtgtgtgcga
     1921 aatcgcccag ttgcggaatg gagcgcgttc gcctgtatga tgaaaagggt aacaggggcc
     1981 gcaaagctgg cacggggctg tttaccgccg cgatgatgga caaatatccc tggctgccga
     2041 tagaggaaga tggtcgcctg cacgatccgg tactacgcga gaatttcatc gcacgtatct
     2101 tcgcgctaca tgaattaaat gcgctacgcg cgcagggctt gagtcgtcac agtttgctcg
     2161 cgtttcatag ccgatacaaa cttcagcttc tcgcccacca ccaggccggc taccgcgaaa
     2221 ttggcccttt cgtcgcgcgt ctgcatgagt gggacgatct ggatgccttc tttgtccgat
     2281 acagagaaaa actgatggct atcctgcgac accccgcttc acgtaaaaat cacaccaatg
     2341 tgctgatgca tatccagggc tattttcacc gcgcgttgaa cagcaggcaa cgcgcggaat
     2401 tacgcgaggt gattctcggc taccgggcgg gccgactacc tatcctggca ccgttaacgc
     2461 tgctgaagca ctatctggcg gaacatccgg atgactatct acgcagccag aattattttg
     2521 agccgtaccc tgatacatta gggctgcgct tagccatcac ctgataaccc tgcgcatcgc
     2581 taacggcggg taaccagccc gccatggtga caatcgcgac aattcaaagg cgatttcgtt
     2641 attgccaccc tgatagcggc tatgaccgcg ccagagcgtt aatcacggtt tccatagcct
     2701 gtttttctaa cgcgctacgt tggatgcgtt gattcgccag cgcggttctt aacacgcccg
     2761 caataacaat atatttaggc tcctgcccca gatcgcgcat ttccagcacg accttgccca
     2821 ccacccggca catctcgcgg tacagttcgt catcttttgt cggttttgtc atacgtttta
     2881 ctcgtcgcca gctcaaacca acagaatata acagtcttct caattaaaca aaatttgatg
     2941 caaatcaaag aaataacgca gtttattatt catggctcat acgttgttcg tattctggtc
     3001 tctggcgagg ccattttttc gaaacgccta atcagttccg ccaggctacc ggcctgcatt
     3061 ttttccatga ctctggcgcg gtgcacctct acggtacgca ccgcgatatt catcgcttcc
     3121 gcaatttcac ggttcataaa cccttttgcc accaggctgg ccagctcacg ctctttcggc
     3181 gtcaactgct ggtaacacag tataatctca cggcgcgcca ccgctgccga tgaaaccgtc
     3241 agcgcacgct ccagcgccgc ctgtagcggt tttaccgata ccggtttttg cagaaaatcg
     3301 acggcgccgc gtttcatctg ctccacggcc atcggtacat cgccatgccc ggtaagaaaa
     3361 acaaccgcca gggtacttcc gcactggcgc aacgcatcat gaacgccctg cccatccagt
     3421 accggcattc gcatatccag taatacgacc ccggcctgat acagactggc ctgcgccaaa
     3481 aaatccgccc cctgcgtcca gcattttacg tcatatccca gactttccag taaaaacgcg
     3541 cacgcgttag tgaccgccgt atcatcatcc agtagatgaa ttgtcgccat ccctgccccc
     3601 atgttcatgt aagaaatgta tcgtgaccac cgttcccgac agaccgtccg gcgcggtctg
     3661 gttcctgatg ctgatatcgc cccgcccata ccgcaccagc cgctggcaaa tcgccagccc
     3721 taagcccatc ccctctttac gggtggtcat aaacggctga aacgcctgac gtaatagcgc
     3781 ctcgtcgatt cccccggcgt tatcctgtaa aacaatactg atgccgtttt cagtgcgttc
     3841 agcaacgacc cataaatggg tggcgcccgc ctgagccgca ttaagaatga tattcgccag
     3901 cacctgttcc agcagcactg acggcagcgt tacgcgcagc gcagcgctaa cctcggtatg
     3961 cagagtcact gtcggaaatt gttgcgccat acgcaacaat tgccagacat gatcaatcgc
     4021 ctcgcgaatg gctatggcct tccacgcttc ggttagcacc gggttgccct gcgcctggct
     4081 gacccagtga cgcaggttac gcagagtatc cgcaccgcgt tgcgcctgct ggtcaatctg
     4141 ctccagcgcc ggcagcaagg gatgctgttc atctgcagcg cgcagtcgaa tcaggcaccc
     4201 ctgggcataa tgtcgaatcg cggaaagcgg ctgattaagc tcatgggcaa acccggaggt
     4261 catttcaccc aacacgctca tttgccgggc ggtttccagc gcccgctcat gctgatgaag
     4321 aactacgcta ttacgttcca gttgctttcc acgtcgacgc accagcagca tgacccaaat
     4381 ataattgagc gtgagcaaca ggaacgccaa aatcacgccg ccgaccatta gctggtgctg
     4441 gattaaccaa cttttgacat ccagccacag tcgacgctgc tgagggtgct gacgaacatc
     4501 acgcagcaac gcttccacct gactggtcga cgctggcgcg ccccagtgaa atgacgcggc
     4561 ggcgggcgcg ttgaatagcg ctcgcgttac gcgatccgcc agcgcatcgc ttaccgcagg
     4621 tagcgccgcg aacgaccagt caggatataa cggcgtactg gttaagcaag gcaggggcgt
     4681 cggtcgggaa agcagcgcga taaagtcctt tttattaatc aatccttcct gatccatatt
     4741 ttctaacagg cacactggca caattgccgc ctgcaccgct ttttcgcgca gcatatagat
     4801 taaggcatcg ccaggaaatc cggtaaaacg aagatgaaaa tcgcgctccg ggcgtaagcc
     4861 cgcgtcgctg agcgctttat agcctaataa atagccgcca aacgcctgag catcaatcgc
     4921 gccgactgtc ttaccgatga gatcatgcgc cgtggtgatg ccgctatcgc gccgggtcaa
     4981 aatcacgctg ccaataacat tgctcaccgc tttcccatcg cgcgtggaac gcagggaagc
     5041 taaccagcgc agcggcgcat ggctgttcag ttggacaaat tgcgccgggt tggttatcac
     5101 aaactgcacg gttccctggt taacggcctc ctgcatttga tgcagatcca gcggctggat
     5161 gtgaaaggtt tcgcctggaa gctgttggct taatgtcttt gccaacggtt gccagtggct
     5221 acgcgtagac gcctcgccgc gcatggccaa aataccgata ttccacgtcc ctgcccacgc
     5281 gccatgacaa agtagcccta ctgccgccaa caccgccagg cgccttacgg ttttacctct
     5341 caccccaata tccctgtcaa ttatgttgtt ttagatcaac aacaagccgg gtatgtggtt
     5401 aaccacaata gagcgcaccc cgtctcgatt tttacactgt aaatcatcaa cattttttat
     5461 tcattacaca tgaaccaaca tcgtgacaaa tgtttcattg ttggcaatgt ggacgggagt
     5521 caatatggac agcagtaaac ggcaatttct ccagcagctc ggcgtcctga ccgctggcgc
     5581 ctcgctggtt ccgctggctg aagcgaaatt tcctttttcg ccggagcggc atgaaggctc
     5641 tccccgacac cgttacgcca tgcttatcga cctgcggcgt tgtatcggct gtcagtcctg
     5701 taccgtaagt tgcactattg aaaaccaaac gccgcagggc gcgtttcgta cgaccgtgaa
     5761 ccaataccag gtccagcgtg aaggtagtca ggaagtcacg aatgtgctgt tgccgcgtct
     5821 gtgcaaccat tgcgataacc ccccctgtgt gccggtctgc ccggtacaag ccacctttca
     5881 gcgggaagac ggcattgtgg tggtggataa caaacgctgc gtcggctgcg cctattgtgt
     5941 ccaggcgtgt ccttacgacg cccgatttat caatcatgaa acgcaaactg ccgataaatg
     6001 cacgttttgc gtccatcgtc tggaagccgg actgttaccc gcttgcgtag agtcctgcgt
     6061 cggcggcgcg cgtattattg gcgatatcaa agatccccat agccgcatcg ccaccatgct
     6121 tcatcaacat cgcgacgcta tcaaggtatt aaagccggaa aacggcacgt cgccccatgt
     6181 tttctacctg ggtctggacg acgcctttgt caccccatta atgggccgtg cgcagcccgc
     6241 gctttggcag gaggtctgaa tgacgcattc actcatcatt gaagaagtgc tggctcaccc
     6301 gcaggacatt agctggctgc cgtgggcggt acaatatttc ttttttattg gcattgccgc
     6361 ctgcgccgca ctgtttgcct gttatcttca ctggcggaaa aaagacgccg caacagaaga
     6421 aaatcgggca ttactgattg ccattacctg tgcgattacc gcaccgctgg cgctgacggc
     6481 ggatctgcac cagaccgccc gcgtctggca tttctatgcc tggccgacgc cctggtcgtg
     6541 gatgccctgg ggagcgttgt tcctgccgct gtttaccgga tttctcgctc tgtggttcct
     6601 ggcgcagcaa ataaaacgat tattcaataa aagttacaac gtcactaaat ggttggcgtt
     6661 agccagcgcg ctttgcgcgg tgggcctgtt gatttatacc ggccgcgaag tctccgttgt
     6721 gctggcgcgc ccaatctggt ttagctacgc cttccccgtg gcgatgtttc ttagcgcctt
     6781 acaggcgttc ttcgcgctga tgattgtcgc cgcccgacgc gactcggtaa ggctgccaaa
     6841 aatactgtgg ggacaactct ggacgctggc ggcgctgggg ctggttgtgg ccatgtgggt
     6901 cagcggcgat acgctttccg gcacggcaat ccgtcagtgg attaccgtcg ccctgtcagc
     6961 caaatattac gctgtcggct ggctagcgct gtgggtattc acactgctgt tctgtagcct
     7021 ggcgctacgt catccgttat cggagctaag acgcgtcctg ctggttctga gcgcgctggc
     7081 gctatgttgg ctgatgcgct ggacattgtt gattcaggta caaaccgtac ccaagttcaa
     7141 cgcgcaattt aacccttaca cgttaccagg cggaacggat ggctggctgg ctattctcgg
     7201 caccttcggc ctgtggatag cgctactgat tagtattcgt gaaacgctga acggactcac
     7261 caggagatta caacatggct aatttaaccc gtcgtcagtg gctaaaagtc ggtctcgccg
     7321 tcggtgggat ggtcactttt ggtctgagct accgtgatgt ggcgaaacgc gcaattgatg
     7381 gcctgttaaa cgggacatcc ggcaaggtaa cgcgcgaccg catctttggc aacgcgttaa
     7441 ttccggaggc gcaggcacaa acgcactggc agcaaaatcc acaacaaacc atcgccatga
     7501 cgcaatgctt cggctgttgg acacagtgcg gtatccgcgc ccgggtaaat gccgatggca
     7561 aagtaatacg catcgccggc aatccctatc accccttgtc gcaggaacac ccgattgact
     7621 cgtccgtccc ttttagcgaa gccatggagc aactggcggg agaaagcggt cttgacgccc
     7681 gctcaaccgc ctgcgcgcgc ggcgccacgc tgctggaaag cctgtacagt ccgctgcgac
     7741 tgcttgaacc gatgaaacgc gtgggtaaac gcggcgaagg gaaatggcag cgcatcagct
     7801 ttgagcagct tattgaagaa gtcgtggaag gcggcgatct gtttggcgaa ggtcatgtgg
     7861 acggactgcg cgctattcat gcgccggata cgccaattga cgcaaagcac cccagtttcg
     7921 ggcccaaaac caatcagtta ctggtcacga ataccagcga cgaaggccgc gatgcgtttc
     7981 tgcgtcgttt tgcgctaaat agcttcggca gcaagaattt cggcgcgcat ggcgcctact
     8041 gtggactggc ttaccgggcc ggctccgggg cattgatggg cgatctggat aaaaacccgc
     8101 atgtcaaacc cgactgggaa aacgtggagt ttgcgctctt tatgggcacc tccccggcac
     8161 agtccggtaa tccctttaaa cgccaggcgc gtcagttggc gagcgcccgg ctgcgtgaga
     8221 attttcaata cgtcgtggtc gcccccgccc tccccttatc aacggtgctc gccgatcctc
     8281 gcggtcgctg gcaaccggtc atgcccggca gcgattcggc gctggcaatg gggatgatcc
     8341 gctggatcat ggataatcaa cgttataatg ctgattatct ggcgattccc ggcgtacagg
     8401 cgatgcagca ggccggcgag caaagttgga ccaacgccac gcacctggtc attgcggatg
     8461 aactgccgac gcttgccgga caacacctga cgctgcgcca tcttacgccc gatggcgaag
     8521 agacccccgt cgtgctgaat accgacggcg agttggtcga tgcgtccact tgccgacagg
     8581 cacggctttt cgtgacgcag tacgttacgc tcgccgacgg ccaacgggtc acggtgaaga
     8641 gcgggttgca acgcctgaaa gaggcggcag aaaagctctc gttggcgcaa tacagcgaac
     8701 agtgcggcgt gccggaagcg caaattatcg cgctggcgga aacctttatc agtcacggac
     8761 gtaaagctgc ggtcatcagt cacggcggca tgatggccgg caatgggttt tataacacct
     8821 ggtcagtcat gatgcttaac gcgctgatcg gcaacctcag cttgtccggc ggcgtctttg
     8881 tcggcggcgg caaattcaac ggcgttagcg acggcccccg ctacaacatg aacagttttg
     8941 ccggaaaagt gaaaccgtcc gggttgagta ttgcccgtag caaaaccgct tataaagcat
     9001 cggaagaata ccgcgacaaa attgccggcg ggcaatcccc ttatccagcc aaagcgccat
     9061 ggtatccctt tgtggcaggc cagcttaccg aactgttgac ctccgcgctc gaaggctatc
     9121 cttatccgct taaagcctgg atttccaata tgagcaaccc gttttacggt gttcccggtc
     9181 tacgcgccgt ggcggaagaa aagctaaaag accctcgccg actgccgctc tttatcgcga
     9241 ttgacgcctt tatgaatgaa acgacggcgc tggcggatta cattgtgccg gatacgcaca
     9301 attttgagag ctggggcttt acggcgccct ggggcggcgt agccagtaaa gccactaccg
     9361 cccgctggcc ggttgtcgcc cccgccactc accgaacggc ggacgggcaa cctgtctcaa
     9421 tggaagcatt ttgtattgcg gtagcaaaac ggctccatct gcccggcttc ggcgaccggg
     9481 cgataaccga tccgcagggc aatacttttc cactgaaccg ggcggaagac ttctatctgc
     9541 gcgtagccgc taatatcgcc tttatgggca agacgccggt cgcgctggca aatcaggaag
     9601 atatttcgct taccggcgtc agccgcattc tgccagcaat tcagcacacg cttaaagctg
     9661 atgaggtcgg tcgcgtggcg tttatctact cgcgtggcgg ccggtttgcg cccgaagata
     9721 gcggctatac ggagcaacgg ttaggtaacg cgtggaaaaa acccttacag atctggaatg
     9781 cagatgtcgc cgcccaccgt cacgccatca ccggggagcg cttcagcggt tgcccggtct
     9841 ggtatccggc gcgtctgtca gatggtcgtg cgattgacga ccagtttccc attggacagt
     9901 ggccgctgaa actgatttca tttaaatcaa ataccatgtc cagctcaaca gccgtcatcc
     9961 cgcgcttaca ccatgtgaag ccagcaaacc tggtggcgct gaatccgcaa gacggcgagc
    10021 gttatggact gcaacatggc gatcgggtac ggatcattac gccgggcggt caggtcgtgg
    10081 cgcaaatcag tttgttaaat ggcgtgatgc caggcgtcat cgccatcgaa cacggatatg
    10141 gccaccgcga gatgggcgca acgcagcact ctctggacgg cgtgcctatg ccgtatgatc
    10201 cacaaatcag ggcaggcata aatcttaacg atctgggctt tgctgatccg acaagaacca
    10261 ttaccaacac ctggctcgac tgggtttctg gcgcggcggt acgtcagggg ctgccggcaa
    10321 aaatcgagcg tatataaccc cagggccgga gagcgatatc gtcttatttc gtcgagggta
    10381 gcgactgata agcgaatgct gtccggctgc atatactcac tgaatcgtgc aagcccaact
    10441 attttacgtt caccccgtca tattacatag aaaatatatg acaacactca caaaactatt
    10501 ttccccttct gtaagcaatt aatatttaac acattggctg cgcttctgat tattgacatt
    10561 catttgggat tacttccggt tgaccgcata atctgtgatt gaattcaccg catgacaata
    10621 ttgccataaa tacaattcaa ctcactaccc ggaggcaata tgtttaaaga agaaagacgt
    10681 catgccatca ttaatttact gataaaggat aatagtgtta gcgtcagtaa actttcagac
    10741 ctttataagg ttagccagga gactattcgt tccgatctac gctatttcca gaaatcaggt
    10801 atgcttcagc gttgctatgg cggagggatt ttaaaccgtg acgcgctgag taagcttatc
    10861 actgaaaata agattgatat ctccagcact atcgccacgc caatccatca ggatgcaaaa
    10921 ctgcaccggg aaaacacaaa aaaagcaggc aaggtgtgtg ttttaggctc attcaatatt
    10981 gatgtttcag caaccgtgcc gtggtttcca caaagcggag aatccattct ggccagtcaa
    11041 tttggattct atcctggcgg taaaggagcc aaccaggctt tagcggcaaa caatgctggt
    11101 gctgcggcgc attttatttt taaagtgggc aaagatcagt tcagcgcatt tgctatgaat
    11161 catattattc aatcaggcac cacctcatac agcgcgtatc aaacagataa agcgcccacc
    11221 ggtagcgcat tgatctatgt ctccgccgtg gatggcgata atattatcgc catctaccct
    11281 ggcgccaata tgatgctcac cacgcaagag attaacgagc aacaccgtta tatcgccgag
    11341 tctgacgtta tgttaatgca gctcgaaacg aacattgaag cgttgactga atttattcgc
    11401 ctgggcaaac aagaaaataa aatgatcatg ctgaatcctg ccccctatac gaaacaggtg
    11461 acgcatttat tatctgatat tgacatcatc acgccgaatg aaactgaagc ctctttttta
    11521 tccggcgtaa ccattactga tattaatgat gcgaaaaaag ccggaaatat tattctgcaa
    11581 tccggggtga aaaaagtcat cattaccctt ggcgcccgtg gttctctgct ctgtgagcac
    11641 gcccgcacgt tgtatattcc tgcgtggagc gccgtggtaa aagatgccgc cggacgcttt
    11701 taatggcgcc ttagccgccg cgctggcgcg acaagcagat atggtcgcag ccattcaata
    11761 tgcctccgct ttcgcttctc tggcggtgga acaagtcggt gcgtcgagta tgcctcagca
    11821 cttgcaggtt ttacatcgaa tgcgtaccca atctaataaa gtcattcaca ttaattaaca
    11881 ggtgacataa tgaaaatctt atttattggc gaatcctggc acattcatat gattcactct
    11941 aaaggttttg atagctttac atcgagcaaa tacgaagaag gcgcagacta tttattatcc
    12001 tgcttacgcc agggtaatat cgatgtggac tacatgcctg cccatattgt gcaaactcgt
    12061 tttccacaaa ccgccgaagc attagcctgc tatgatgcga tcgtcatcag tgatatcggt
    12121 agcaatacgt tcctgttaca aaacagaacc ttttataata tggacattat tcctgatgca
    12181 ttacaactta tcgccgatta tgttgctgag ggcggcggtc tgttaatgat cggcgggtat
    12241 ttatccttta cgggaataga agcaaaagcc aattataaaa atacggttct ggcggaggta
    12301 ttgccggttg atatgctgga tgtagatgac cgcgtagaac taccgcaagg atgtaaagca
    12361 gtaaatactg cggtaaaaca tgttattacc cagccattta gcgaatggcc gccgctgttg
    12421 ggctataaca agcttatcgc caaagaaaat agtcaggtcc ttgctgaaat taatggcgat
    12481 ccactgttag ttatgggtac ttaccataaa gggaaagtat gttgctttgc cagtgattgt
    12541 tcgccgcact ggggaagtcc gcagtttctg caatgggaac attacgccac cttctggtgt
    12601 aatgttttac acacaataaa aaaataatat tacccaggcg aatataaatt tcgcctgcc
//
LOCUS       DAJVBX010000136        12523 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.136, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000136 DAJVBX010000000
VERSION     DAJVBX010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 12523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12523
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.136"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            99..1616
                     /gene="caiT"
                     /locus_tag="OPV72_003156"
     CDS             99..1616
                     /gene="caiT"
                     /locus_tag="OPV72_003156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-carnitine/gamma-butyrobetaine antiport BCCT
                     transporter"
                     /protein_id="HCR9915378.1"
                     /translation="MKNEKRKSGIEPKVFFPLLIIVGILCWLTVRDLDAANVVINAVF
                     SYVTNVWGWAFEWYMVVMLFSWFWLVFGPYAKKRLGDEKPEFSTASWIFMMFASCTSA
                     AVLFWGSIEIYYYISTPPFGLEPNSTGAKEIGLAYSLFHWGPLPWATYSFLSVAFAYF
                     FFVRKMDVIRPSSTLVPLVGEKHAKGLFSTIVDNFYLVALIFAMGTSLGLATPLVTEC
                     MQWLFGIPHTLQLDAIIITCWIILNAICVACGLQKGVRIASDVRSYLSFLMLGWVFIV
                     SGASFIMNYFTDSVGMLLMHLPRMLFYTDAIGKGGFPQGWTVFYWAWWVIYAIQMSIF
                     LARISRGRTVRELCFGMVMGLTASTWILWTVLGSNTLLLMDKNILNIPQLIEQHGVAR
                     AIIETWAALPLSTATMWGFFILCFIATVTLINACSYTLAMSTCREVRDGEEPPLLVRI
                     GWSVLVGIIGIVLLALGGLKPIQTAIIAGGCPLFFVNIMVTLSFIKDAKVHWKDK"
     gene            1651..2793
                     /gene="caiA"
                     /locus_tag="OPV72_003157"
     CDS             1651..2793
                     /gene="caiA"
                     /locus_tag="OPV72_003157"
                     /EC_number="1.3.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crotonobetainyl-CoA dehydrogenase"
                     /protein_id="HCR9915379.1"
                     /translation="MDFNLNDEQELFVAGIRELMASENWEAYFAECDRDSVYPERFVK
                     ALADMGIDSLLIPEEHGGLEAGFVTVAAVWMELGRLGAPTYVLYQLPGGFNTFLREGT
                     QEQIDKIMAFRGTGKQMWNSAITEPGAGSDVGSLKTTYTRKNGKVYLNGSKCFITSSA
                     YTPYIVVMARDGASPDKPVYTEWFVDMSKAGIKVNKLEKLGLRMDSCCEITFDDVELD
                     EKDMFGREGNGFNRVKEEFDHERFLVALTNYGTAMCTFEDAARYANQRVQFGEAIGRF
                     QLIQEKFAHMAIKLNSMKNMLLEAAWKADNGTITSGDAAMCKYFCANAAFEVVDTAMQ
                     VLGGVGIAGNHRITRFWRDLRVDRVSGGSDEMQILTLGRAVLKQYR"
     gene            2905..4122
                     /gene="caiB"
                     /locus_tag="OPV72_003158"
     CDS             2905..4122
                     /gene="caiB"
                     /locus_tag="OPV72_003158"
                     /EC_number="2.8.3.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-carnitine CoA-transferase"
                     /protein_id="HCR9915380.1"
                     /translation="MNHLPMPTFGPLAGVRVVFSGIEIAGPFAGQMFAEWGAEVIWIE
                     NVAWADTIRVQPNYPQLSRRNLHALSLNIFKDEGREAFLKLMETTDIFIEASKGPAFA
                     RRGITDEVLWEHNPKLVIAHLSGFGQYGTEEYTNLPAYNTIAQAFSGYLIQNGDVDQP
                     MPAFPYTADYFSGMTATTAALAALHKVRETGKGESIDIAMYEVMLRMGQYFMMDYFNG
                     GEICPRMTKGKDPYYAGCGLYKCADGYIVMELVGITQINECFKDIGLAHILGTPEVPE
                     GTQLIHRVECPYGPLVEEKLDAWLAAHTIADVQARFAELNIACAKVLTIPELEGNPQY
                     VARESITQWQTMDGRTCKGPNIMPKFKNNPGKIWRGMPSHGMDTAAILKNIGYSEADI
                     KELVGKGLAKVED"
     gene            4185..5738
                     /gene="caiC"
                     /locus_tag="OPV72_003159"
     CDS             4185..5738
                     /gene="caiC"
                     /locus_tag="OPV72_003159"
                     /EC_number="6.2.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crotonobetaine/carnitine-CoA ligase"
                     /protein_id="HCR9915381.1"
                     /translation="MDIVGGQNLRQMWDDLAGMYGDKTALIFESCEGIVRQFSYASLN
                     EEINRTANLFYYLGIRKGDRVALHLDNCPEFIFCWFGLAKIGAIMVPINARLLGEESA
                     WILQNSQVSLLVTSAQFYPMYREIRQDNSTPLNHICLIGEQLPADDGVSHFSQLQARQ
                     SATLCYTPALSTDDTAEILFTSGTTSRPKGVVITHYNLRFAGYYSAWQIALRDDDVYM
                     TVMPAFHIDCQCTAAMPAFSAGSTFVLLEKYSARAFWDQVRKYQATVTECIPMMIRTL
                     MVQPATPTDRQHHLREVMFYLNLSAQEKDAFTERFGVRLLTSYGMTETIVGIIGDRPG
                     DKRRWPSIGRVGFSYEAEIRDDQNRPLPAGEIGEICIKGIPGKTIFKEYYMQPEATAR
                     ALEPEGWLHTGDSGYQDEDGYFYFVDRRCNMIKRGGENVSCVELENIISAHPKIQDIV
                     VVGIKDAIRDEAIKAFIVLNEGETLSEAEFFSFCENNMAKFKVPSFMEIRTDLPRNCS
                     GKIIKKNLK"
     gene            5792..6577
                     /gene="caiD"
                     /locus_tag="OPV72_003160"
     CDS             5792..6577
                     /gene="caiD"
                     /locus_tag="OPV72_003160"
                     /EC_number="4.2.1.149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crotonobetainyl-CoA hydratase"
                     /protein_id="HCR9915382.1"
                     /translation="MSESLHLTRNGPILEITLDRPKANAIDAKTSFAMGEAFLNFRDD
                     PELRVAIITGGGEKFFSAGWDLKAAAEGEAPDADFGPGGFAGLTEIFDLDKPVIAAVN
                     GYAFGGGFELALAADFIVCAENASFALPEAKLGIVPDSGGVLRLPKLLPPAIVNEMVM
                     TGRRMSAEEALRWGIVNRVVSQSELMESARELAQQLVNSAPLAIAALKEIYRATSEMP
                     VEEGYRYIRSGVLKHYPSVLHSEDALEGPQAFAEKRAPVWKGR"
     gene            6689..7285
                     /gene="caiE"
                     /locus_tag="OPV72_003161"
     CDS             6689..7285
                     /gene="caiE"
                     /locus_tag="OPV72_003161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carnitine operon protein CaiE"
                     /protein_id="HCR9915383.1"
                     /translation="MSYYAFEGLIPVVHPDAFVHPSAVLIGDVIVGAGVYIGPLASLR
                     GDYGRLILEAGSNLQDGCIMHGYCDTDTIVHENGHIGHGAILHGCVVGRDALVGMNSV
                     IMDGAVIGEESIVAAMSFVKAGFQGEARQLLVGSPARVLRQVTDQELHWKRLNTKEYQ
                     DLAIRCRTGLSETKPLTQVEENRPRLKGTTDVKPKSAQ"
     gene            complement(7363..7758)
                     /gene="caiF"
                     /locus_tag="OPV72_003162"
     CDS             complement(7363..7758)
                     /gene="caiF"
                     /locus_tag="OPV72_003162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carnitine metabolism transcriptional regulator
                     CaiF"
                     /protein_id="HCR9915384.1"
                     /translation="MCEKYVERPLYLLIADWMMAENRWITAREISRQFDIEHCKAINT
                     LSYILSEVGEIVCEVKMIPNQIAGRGCQCQRLVKVVSIDSQLYRRLNHNLQERKVSVA
                     KAPRLSAVPPTELNREQKWQMMLSKSMRR"
     gene            complement(8032..11259)
                     /gene="carB"
                     /locus_tag="OPV72_003163"
     CDS             complement(8032..11259)
                     /gene="carB"
                     /locus_tag="OPV72_003163"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HCR9915385.1"
                     /translation="MPKRTDIKSILILGAGPIVIGQACEFDYSGAQACKALREEGYRV
                     ILVNSNPATIMTDPEMADATYIEPIHWEVVRKIIEKERPDAVLPTMGGQTALNCALEL
                     ERQGVLEEFGVTMIGATADAIDKAEDRRRFDIAMKKIGLDTARSGIAHTMEEALAVAA
                     DVGFPCIIRPSFTMGGTGGGIAYNREEFEEICERGLDLSPTNELLIDESLIGWKEYEM
                     EVVRDKNDNCIIVCSIENFDAMGIHTGDSITVAPAQTLTDKEYQIMRNASMAVLREIG
                     VETGGSNVQFAVNPKNGRLIVIEMNPRVSRSSALASKATGFPIAKVAAKLAVGYTLDE
                     LMNDITGGRTPASFEPSIDYVVTKIPRFNFEKFAGANDRLTTQMKSVGEVMAIGRTQQ
                     ESLQKALRGLEVGATGFDPKVSLDDPEALTKIRRELKDAGADRIWYIADAFRAGLSVD
                     GVFNLTNIDRWFLVQIEELVRLEEKVTEVGITGLNADFLRQLKRKGFADARLAKLAGV
                     REGEIRKLRDQYDLHPVYKRVDTCAAEFATDTAYMYSTYEDECEANPSVDRDKIMVLG
                     GGPNRIGQGIEFDYCCVHASLALREDGYETIMVNCNPETVSTDYDTSDRLYFEPVTLE
                     DVLEIVRIEKPKGVIVQYGGQTPLKLARALEAAGVPVIGTSPDAIDRAEDRERFQHAV
                     DRLKLKQPANATVTAIEQAVEKAKEIGYPLVVRPSYVLGGRAMEIVYDEADLRRYFQT
                     AVSVSNDAPVLLDRFLDDAVEVDVDAICDGEMVLIGGIMEHIEQAGVHSGDSACSLPA
                     YTLSQEIQDVMRQQVQKLAFELQVRGLMNVQFAVKDNEVYLIEVNPRAARTVPFVSKA
                     TGVPLAKVAARVMAGKSLTEQGVTQEIIPPYYSVKEVVLPFNKFPGVDPLLGPEMRST
                     GEVMGVGRTFAEAFAKAQLGSNSTMKKQGRALLSVREGDKERVVDLAAKLLKQGFELD
                     ATHGTAIVLGEAGINPRLVNKVHEGRPHIQDRIKNGEYTYIINTTAGRRAIEDSRVIR
                     RSALQYKVHYDTTLNGGFATTMALNADATEKVTSVQEMHAQIKKS"
     gene            complement(11275..12423)
                     /gene="carA"
                     /locus_tag="OPV72_003164"
     CDS             complement(11275..12423)
                     /gene="carA"
                     /locus_tag="OPV72_003164"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HCR9915386.1"
                     /translation="MIKSALLVLEDGTQFHGRAIGATGSAVGEVVFNTSMTGYQEILT
                     DPSYSRQIVTLTYPHIGNVGTNEADEESSQVHAQGLVIRDLPLIASNFRNTEDLSSYL
                     KRHNIVAIADIDTRKLTRLLREKGAQNGCIIAGDSPDAKLALEKAKAFPGLNGMDLAK
                     EVTTAETYRWTQGSWTLKDGLPEAKSEDDLPFHVVAYDFGAKRNILRMLVDRGCRLTV
                     VPAQTSAEEVLKMNPDGIFLSNGPGDPAPCDYAIEAIKKFLQTDIPVFGICLGHQLLA
                     LASGAKTVKMKFGHHGGNHPVKDMDRNVVMITAQNHGFAVDEDSLPANLRVTHKSLFD
                     GTLQGIHRTDKPAFSFQGHPEASPGPHDAAPLFDHFIELIKHYRSSAK"
BASE COUNT         2804 a         3363 c         3411 g         2945 t
ORIGIN      
        1 gaggttaaaa acttatcaac aaatcattaa taataaataa acaaacgttc atgaactggc
       61 acgctaaata aatttcgttt tcacactgga attcacttat gaaaaatgaa aagagaaaat
      121 cgggaattga accgaaggtt ttttttccgc tattaataat tgtcgggata ctttgctggc
      181 taacagtcag agatcttgat gccgctaacg tcgttattaa tgcggtattc agttatgtca
      241 ccaacgtctg gggttgggca tttgaatggt atatggtcgt catgctcttc agctggttct
      301 ggctggtttt tggcccctat gccaaaaaga gattaggtga cgaaaaaccg gagtttagca
      361 ccgccagctg gattttcatg atgttcgcct cctgtacatc cgctgcggtt ctgttctggg
      421 gctctattga gatctactac tatatctcca ccccgccgtt cggcctggaa cccaattcca
      481 cgggcgcgaa agagataggc ctggcgtaca gcctgttcca ctgggggccg ctaccgtggg
      541 caacctatag cttcctttcc gtggccttcg cctacttctt ctttgtacgc aagatggatg
      601 tcatccgccc cagctccacg ctggtaccgc tcgtcggtga aaagcatgcg aaagggttgt
      661 tcagtaccat cgtcgataac ttctacctgg tggcgctgat cttcgcgatg ggcaccagcc
      721 tcggtctggc taccccgctg gtcaccgagt gtatgcaatg gctgttcggt attccgcata
      781 cgctgcaatt ggatgccatc atcattacct gctggatcat tctgaacgcg atttgcgtgg
      841 cctgcggcct gcaaaaaggg gtcagaatcg ccagcgatgt gcgtagctac ctgagcttcc
      901 tgatgctcgg ctgggtgttt atcgtcagcg gcgccagctt catcatgaac tacttcaccg
      961 actccgtcgg gatgctgtta atgcacctgc cacggatgct gttctatacc gacgccatcg
     1021 gtaaaggcgg cttcccacag ggctggaccg ttttctactg ggcgtggtgg gttatttacg
     1081 ccatccagat gagtatcttc ctggcccgta tttcccgtgg tcgtaccgta cgtgaactgt
     1141 gcttcgggat ggtgatgggt ctgaccgcgt ctacctggat cctgtggaca gtccttggca
     1201 gtaacacgct gctgctgatg gataaaaaca tcctcaacat cccgcaactg attgagcaac
     1261 acggcgtggc gcgcgccatt atcgaaacct gggcagcctt gccgctcagc accgccacca
     1321 tgtggggctt cttcatcctc tgctttattg ccaccgtcac gctgattaac gcctgctctt
     1381 acaccctggc gatgtcgacc tgtcgcgaag ttcgcgatgg tgaagagccg cctctgttag
     1441 tacgcatcgg ctggtcggtg ctggtcggca tcatcggtat cgttctgctg gcgctgggtg
     1501 ggttgaagcc gattcagacc gcgattatcg ccggaggatg cccgctgttc ttcgtcaaca
     1561 ttatggtgac gctgtccttt attaaagacg ccaaagtgca ctggaaagac aagtaattct
     1621 tattaaccca attgatcaag aggctgaaag atggatttca acttaaatga cgaacaggag
     1681 ctgtttgtcg ccggtattcg cgaactgatg gccagtgaga actgggaagc ttattttgcc
     1741 gagtgcgatc gtgacagcgt ctaccctgag cgttttgtaa aagcgctggc ggatatgggt
     1801 attgatagcc tgctgatccc ggaagaacac ggcggtctgg aagcgggttt tgttaccgtc
     1861 gccgccgtct ggatggaact gggacgtctt ggcgcgccaa cttacgtgtt gtaccaattg
     1921 ccgggaggtt ttaacacttt cctgcgtgaa gggactcagg agcaaattga taaaatcatg
     1981 gcgttccggg gcaccggtaa gcagatgtgg aactctgcta tcaccgaacc gggagcggga
     2041 tcggatgttg gtagtctgaa aaccacttat acacgcaaaa atggtaaggt ttatctcaat
     2101 ggcagtaagt gctttatcac cagtagcgcc tataccccgt acatcgtggt catggcgaga
     2161 gacggtgcat cgccggataa accggtttac accgagtggt ttgtggacat gagcaaagcg
     2221 ggtatcaagg tcaacaaact ggagaaactc ggtctgcgca tggatagctg ctgtgaaatc
     2281 acctttgacg acgttgaact ggacgagaaa gacatgttcg gtcgggaagg taacggcttc
     2341 aaccgcgtga aagaagagtt tgaccatgaa cgcttcctcg tcgcgctgac caactacggt
     2401 accgcaatgt gcacttttga agacgctgcg cgttacgcta atcagcgcgt gcagtttggt
     2461 gaagctattg gccgtttcca gctgattcag gagaagtttg cgcatatggc gatcaaactg
     2521 aactccatga aaaatatgct gctggaagcc gcgtggaaag cagataacgg cactattacc
     2581 tccggcgacg cggccatgtg caaatacttc tgcgccaacg ccgcgtttga agtggtagac
     2641 accgccatgc aggtactggg aggtgttggt atcgcgggca accaccgcat cacgcgtttc
     2701 tggcgtgacc tgcgcgttga ccgtgtttct ggtggttctg acgaaatgca gatcctgacg
     2761 ttgggtcgtg cggtactcaa gcaataccgc taatcgatcc cttgtaggcc tgataagacg
     2821 cggggcgtcg ccatcaggca atcatgccgg atggcgctgt gcttatccgg cctacatacc
     2881 gcaaaaaatg ccaggagaaa aacgatgaat catttaccaa tgccaacctt tggtcctctt
     2941 gctggggtac gcgttgtttt ttcagggatc gaaatcgccg gtccgttcgc cggacagatg
     3001 ttcgccgaat ggggcgccga ggttatctgg attgaaaacg tcgcatgggc cgataccatc
     3061 cgcgtacagc ctaactaccc gcagctctca cgccgcaacc tgcacgccct gtcgctgaat
     3121 attttcaaag atgaaggtcg ggaagcgttt ctgaaactga tggaaaccac cgatattttc
     3181 attgaagcca gtaaaggccc ggcctttgcc cgccgtggta ttactgatga agtgctgtgg
     3241 gaacataacc cgaaactggt cattgcccac ctttccggct tcggccagta tggtaccgag
     3301 gagtacacca atcttccggc gtataacacc atcgcgcagg cattcagtgg ttatctgatc
     3361 caaaacggcg acgttgacca accgatgcca gccttcccgt ataccgccga ttacttctcc
     3421 gggatgaccg cgacgacagc cgcgctggca gccctgcaca aagtacgcga aacgggtaaa
     3481 ggtgaaagca tcgatatcgc catgtacgaa gtgatgctgc gcatgggtca gtatttcatg
     3541 atggactact tcaacggcgg cgaaatctgt ccacgtatga cgaaagggaa agacccctac
     3601 tacgccggtt gcggcctgta taaatgcgcc gatggttaca tcgtcatgga gttggtcggc
     3661 atcacgcaaa tcaacgagtg ttttaaagat attggcctgg cgcacattct cggtacgccg
     3721 gaagttccgg aaggcacgca gctcatccat cgcgtggaat gcccttacgg cccgctcgtc
     3781 gaagagaaac tggacgcctg gctggcagca cataccatcg ccgacgttca ggcgcgtttt
     3841 gctgagctga atatcgcctg tgcgaaggtg ctcaccattc cggaactgga aggtaacccg
     3901 cagtacgttg cccgcgaatc gattactcag tggcaaacaa tggacggtcg cacctgtaaa
     3961 gggccgaaca tcatgccgaa atttaaaaac aacccgggga aaatctggcg tggcatgcca
     4021 tcacacggca tggataccgc cgccattctg aaaaacattg gttatagcga agcagatatt
     4081 aaggaactgg tcggcaaagg cctggccaaa gttgaggatt aaacgcgatg cgctactcgg
     4141 ttttccggtt agcgctcacg cctgatttca gtggataaag caatatggat atcgttggcg
     4201 gacaaaactt acgtcagatg tgggacgacc tggccgggat gtacggagat aaaacggcgt
     4261 taattttcga atcctgtgag ggaatcgttc ggcagtttag ctatgcttcg ctcaatgaag
     4321 agattaaccg cacggcgaac cttttttatt acttagggat ccgcaagggt gatagggtcg
     4381 cgctgcatct ggataactgt ccggaattca tcttttgctg gtttggactg gcaaaaatcg
     4441 gcgccattat ggtgccgatt aatgcccgct tactgggcga agaaagcgcc tggatcctgc
     4501 aaaacagcca ggtgagtctg ctggttacca gcgcccagtt ttatcctatg taccgtgaaa
     4561 tacgccagga caatagcact ccgcttaatc atatctgtct gattggcgag cagcttccgg
     4621 ctgacgacgg cgtgagccac ttttcccaac tacaagcacg ccagtcggcc acgctgtgct
     4681 atacgcccgc gttatccact gacgatacgg cggaaattct gtttacctcc ggtaccacct
     4741 cgcgtccaaa aggggtggtg attacccact ataacctgcg ctttgcaggc tattactctg
     4801 cctggcaaat cgccctgcgc gatgatgacg tgtacatgac ggtgatgccc gcttttcata
     4861 tcgactgcca gtgtaccgcc gcaatgccag ccttttccgc cggcagcacc tttgtgctcc
     4921 tggagaagta cagcgccagg gccttctggg atcaggtacg taaatatcag gcgacggtga
     4981 ccgagtgcat cccgatgatg atccgcacgc tgatggtcca gcccgccacg ccaacggaca
     5041 ggcagcatca tctgcgcgaa gtgatgttct atctcaattt atccgcgcag gaaaaagacg
     5101 cctttaccga acgctttggc gtcaggctgc tgacctctta tggtatgact gaaaccattg
     5161 tcggaattat tggcgaccgt cccggagaca aacgacgctg gccttccatt ggtcgcgtgg
     5221 gctttagcta tgaagctgaa attcgcgacg atcaaaatcg cccgctgccc gccggagaaa
     5281 ttggcgaaat ctgtattaaa ggcatccccg gcaagactat cttcaaagag tattacatgc
     5341 agccggaggc aaccgccagg gcgctggaac cagagggctg gttacatacc ggtgattcgg
     5401 gttaccagga tgaggatggc tatttctatt ttgtcgacag acgctgcaac atgattaaac
     5461 gcggcgggga aaatgtctcc tgcgtcgagc tggaaaatat tatttctgcg catccgaaaa
     5521 ttcaggacat tgtggtggtc ggtattaaag acgcgatccg tgatgaagcc attaaagcgt
     5581 ttatcgtcct taatgaaggt gaaacattaa gcgaggccga gtttttcagc ttctgcgaaa
     5641 acaatatggc gaaattcaaa gttccctctt ttatggagat cagaactgac ctgccacgca
     5701 actgttcagg aaaaataatc aaaaaaaatc tgaaataaac cttccggcag gaatccctcc
     5761 cgccgggaaa ctatttatct ggagatgaac tatgagtgag tcattacatc tgacccgtaa
     5821 cggcccgatc ctggaaatta ccctcgaccg acctaaagcg aatgccattg atgcgaaaac
     5881 cagttttgcg atgggtgaag cttttcttaa tttccgtgac gacccggaat tacgcgtagc
     5941 aatcattacc ggcggcgggg agaaattctt ttctgcgggc tgggacttaa aagcggcagc
     6001 ggaaggtgaa gcgccggatg ccgattttgg tcccggcggc tttgccggtt taaccgaaat
     6061 atttgacctc gataagccgg ttatcgccgc ggtgaacggc tacgcatttg gtggcggttt
     6121 tgagctggcg ctggcggcag actttattgt ctgcgccgaa aacgccagct tcgcgctgcc
     6181 ggaagccaag ctcggcatcg tgcctgacag cggcggcgta ttgcgtctgc ctaagctgct
     6241 gccaccggct atcgtcaacg aaatggtaat gaccggcaga cgaatgagcg ccgaagaagc
     6301 gctgcgttgg gggatcgtga accgcgttgt cagccagagc gaactgatgg agagcgcgcg
     6361 cgaactggcg caacaactgg tcaatagcgc tccgctggct atcgcggcgc tgaaagagat
     6421 ttatcgcgcg accagtgaaa tgccggttga agaaggctac cgctacatcc gcagcggcgt
     6481 gctgaaacat tatccgtcgg tactgcattc agaagatgcg ctcgaaggac cgcaggcatt
     6541 tgccgaaaaa cgcgctccgg tgtggaaagg tcgttaatgt gactatgccg gatggcgctt
     6601 cgcttatccg gcctacaaca catgcacaac cgtaggccgg ataaggtatt tacgccgcca
     6661 tccgacaaaa aaaaaccgag gtacaaccat gagctattac gcctttgaag gactgatccc
     6721 ggtggtgcat ccggacgcgt ttgtccatcc cagcgccgtg ctgattggcg atgtcatcgt
     6781 gggcgccggt gtttatattg gcccactcgc gtcattgcgt ggggattatg gtcgcctgat
     6841 cctggaggca ggctctaatc tgcaggatgg ctgcattatg catggctact gcgataccga
     6901 taccatcgtg catgaaaacg gccatatcgg ccacggcgct attctacatg gctgcgtggt
     6961 gggacgggat gccctggtcg gcatgaatag cgtcattatg gacggcgcag tgattggcga
     7021 agagagcatt gtcgccgcca tgagttttgt caaagccgga tttcagggtg aggcaaggca
     7081 actgctggtg ggatcaccgg cgcgcgtact acgccaggtt acggaccagg agctgcactg
     7141 gaaacgcctc aataccaaag aatatcagga tcttgcgatc cgttgtcgaa cggggttatc
     7201 tgaaacgaag ccgttaacgc aggtcgaaga aaaccgaccg cgcctgaaag gcacgacgga
     7261 cgtgaagcca aaatcagcac agtaattgat gccggatgcg ctcacgctta tccggcctac
     7321 gcgtcaatta ccgtttaccc cgccagcagg ttaaacagac aattagcgac gcatactctt
     7381 ggagagcatc atctgccatt tctgctcacg gtttagctct gtggggggaa cggcagacag
     7441 ccgcggcgct ttcgccacgc tcacttttct ttcctgcaaa ttatgattca atcggcgata
     7501 gagttgagag tcgatactca cgactttcac cagacgctgg cactggcagc ctcgtcctgc
     7561 aatttggtta gggatcatct tcacttcaca aacaatttcc cccacttctg acagaatata
     7621 ggagagcgta ttaattgctt tgcaatgttc aatatcaaat tgacgggaaa tctccctggc
     7681 agtgatccat cggttctctg ccatcatcca gtcagcaatt aacaaataaa gcggtctttc
     7741 aacatatttt tcacacataa gcacaccatt tcacaaatta aaaatctggc tacggcctgt
     7801 ccaaactaat aaaaactaag ccatattaaa attgtggata tgaaagatag tatgcgactt
     7861 aaatattgat tagtgtgagc aatatcgtgc ttattacatt gaaaatgtgg ttacggaaac
     7921 ggacttctcc aggaatgacc ttacgcaaga taaaaaaagg gtttctttac agaaaccctt
     7981 tcaacattat attacaggtt cggttagagc aatatccgcc gcccccttgg tttacgactt
     8041 tttgatctgc gcgtgcattt cctgcaccga ggttaccttc tcggtggcat cggcattgag
     8101 cgccatcgtc gtggcaaaac cgccgttcag cgtggtgtca taatgcacct tatactgcaa
     8161 cgcgctgcgg cgaatcaccc ttgagtcttc aatcgcccgg cggcctgcgg tggtgttgat
     8221 gatgtaggta tattcgccat tcttgatgcg gtcctgaatg tgcggacgac cttcgtgcac
     8281 cttgttcacc agacgcgggt tgataccggc ttcgcccagc acaatcgccg taccgtgggt
     8341 ggcatccagc tcgaagcctt gtttcagcag cttagcggcc aggtccacca cgcgctcttt
     8401 gtcgccttcg cgaaccgaga gcaacgcacg gccctgtttc ttcatagtgg agttactgcc
     8461 cagctgtgcc ttggcgaacg cttccgcgaa ggtacggccc acgcccatca cttccccggt
     8521 ggagcgcatt tctggcccta acagcgggtc aacgcccggg aatttgttga acggcagtac
     8581 cacttctttc accgagtagt acggcgggat aatttcttga gtcacgccct gctcggtcag
     8641 cgatttgccg gccatcacgc gcgccgccac tttcgccagc ggcacgccgg tggctttgga
     8701 gacgaacggc acagtacgcg ccgcacgcgg gttgacttca atcaggtaga cttcgttgtc
     8761 tttcaccgca aactgcacgt tcatcaggcc gcgcacctgc aactcgaagg ccagcttctg
     8821 cacctgctgg cgcatcacat cctgaatttc ctggcttagc gtgtaggccg gcagagaaca
     8881 ggcggagtcg ccggagtgta cgcccgcctg ctcgatgtgc tccatgatac cgccaatcag
     8941 caccatttcg ccgtcgcaga tagcgtccac gtccacttca accgcgtcat caaggaagcg
     9001 atccagcagc accggcgcat cgttagagac gctgaccgcc gtctggaagt agcgacgcag
     9061 atcggcttcg tcatagacaa tttccatcgc ccggccgccc agcacgtaag aaggacgcac
     9121 caccagcggg tagccgatct ctttcgcttt ttcgacagcc tgttcaatgg cggtgacggt
     9181 ggcgttggcc ggttgcttca gcttcagacg gtcaaccgcg tgctggaagc gctcgcggtc
     9241 ttccgcgcgg tcgatggcgt ccgggctggt gccgataacc ggcacgcctg ccgcttccag
     9301 cgcgcgcgcc agctttagcg gggtctggcc gccgtactgc acgataacgc ctttcggctt
     9361 ctcgatacgc acgatttcca gcacgtcttc cagcgtcacc ggctcgaagt acaggcggtc
     9421 ggaagtgtcg tagtcggtag agacggtttc cgggttacag ttgaccatga tggtctcgta
     9481 accgtcttcg cgcagcgcca gcgaggcgtg tacgcagcag tagtcaaact caatgccctg
     9541 gccgatacgg ttcgggccgc cgccgaggac catgatttta tcgcggtcaa cggacgggtt
     9601 cgcttcgcac tcatcttcat aagtggagta catataggcg gtgtcggtgg cgaattccgc
     9661 cgcgcaggta tccacacgct tgtagaccgg gtgcaggtca tactggtcgc gcagcttacg
     9721 gatttccccc tcgcgcacgc ccgccaattt tgccagacgc gcatcggcaa aacctttacg
     9781 cttgagctga cgcaggaagt cggcgttgag gccagtaatc ccgacttcag ttactttctc
     9841 ttccagacgc accagctctt caatttgcac caggaaccag cggtcgatgt tggtcaggtt
     9901 gaacacgccg tcgacggaga ggcctgcgcg gaaggcatcg gcgatatacc agatacgatc
     9961 tgcgcccgca tctttcagct cgcggcggat tttggtcagc gcttccgggt cgtcgaggct
    10021 gactttcggg tcgaagccgg tggcgccgac ttccaggccg cgcagcgctt tttgcaggga
    10081 ttcctgctgc gtgcggccaa tcgccatcac ttctccgacc gatttcatct gggtggtcag
    10141 acggtcgttg gcaccggcga atttctcgaa gttaaagcgc ggaattttgg tcacaacgta
    10201 gtcgatggac ggctcgaagg aggccggagt acgcccgccg gtgatgtcgt tcatcagttc
    10261 gtcaagggtg taacctaccg ccagtttggc ggccactttg gcaatcggga aaccggtggc
    10321 tttcgacgcc agcgccgagg agcgggagac gcgcgggttc atttcgataa cgatcagacg
    10381 accgtttttc gggttcactg cgaactggac gttagaaccg ccggtttcga cgccgatttc
    10441 acgcagtacc gccatcgagg cgttacgcat gatttgatat tctttgtcgg tcagagtctg
    10501 ggcgggcgcc acggtgatcg agtccccagt atggataccc atcgcatcga aattttcgat
    10561 agagcagacg atgatgcagt tgtcgttttt atcacgcacc acttccatct cgtactcttt
    10621 ccagccgatc agcgattcat caatcagcaa ttcgttggtt ggcgagagat ccagaccgcg
    10681 ttcgcagatt tcttcgaact cttcacggtt gtaagcgata ccgccgccgg tgccgcccat
    10741 ggtaaagcta ggccggatga tgcacgggaa gcccacgtca gcggcaaccg ccagcgcttc
    10801 ttccatggtg tgcgcgatac cggaacgcgc ggtgtcgaga ccaattttct tcatggcgat
    10861 atcgaagcga cgacggtctt cggctttatc aatggcgtcg gcggtggcgc caatcatggt
    10921 gacgccgaac tcttcgagca cgccctgccg ctccaactcc agcgcgcagt tcagcgcggt
    10981 ctggccgccc atggtcggca gcaccgcatc cggacgctct ttttcgatga ttttgcgcac
    11041 cacttcccag tgaatcggct cgatgtaggt ggcatcggcc atttccgggt cggtcatgat
    11101 ggtggccggg ttagagttca ccagaataac gcggtagcct tcttcgcgca gcgctttaca
    11161 cgcctgagcg ccggagtagt caaactcaca cgcctgaccg ataacaatcg ggcccgcgcc
    11221 cagaatcagg atgcttttta tatctgtacg ttttggcatt ttgttggctc ctgattattt
    11281 tgctgaagaa cggtagtgct taatcaattc gataaagtgg tcgaacagcg gcgccgcatc
    11341 gtgcgggccc gggctcgcct ccgggtgtcc ctggaagctg aacgccggtt tgtcggtacg
    11401 gtgaatgccc tgcagggtgc cgtcgaacag cgacttgtgg gtcacgcgca ggttggcggg
    11461 cagcgagtct tcatccaccg caaatccgtg gttctgcgcg gtgatcatca ccacgtttct
    11521 gtccatatct tttaccggat ggttgccgcc gtgatggccg aacttcatct taacggtctt
    11581 cgcaccgctc gccagcgcca gcagttgatg gccgaggcag atgccgaaca caggaatgtc
    11641 ggtctggagg aatttcttaa tcgcctcgat ggcgtagtcg cacggcgccg ggtcgccagg
    11701 gccgttcgac aggaagatgc cgtccggatt cattttcagc acctcttcag cagaggtttg
    11761 cgctggcacc accgtcaggc ggcagccgcg atccaccagc atacgtagaa tgttgcgctt
    11821 ggcgccaaaa tcgtaggcca ccacgtggaa cggcaggtca tcctcagatt tcgcttccgg
    11881 taaaccgtct ttcagcgtcc agctaccctg cgtccagcgg taagtttccg ccgtggtcac
    11941 ttctttcgcc agatccatac cgttcagtcc aggaaatgct ttcgcttttt ccagcgccag
    12001 cttcgcatcc gggctatcgc ctgcaatgat gcagccgttc tgtgcgcctt tctcacgcag
    12061 cagtcgggtc agcttgcggg tatcgatatc ggcaatcgcc acgatgttat ggcgtttcag
    12121 gtaagaagag aggtcttcgg tgttacggaa gttgctggca atcaacggca gatcgcgaat
    12181 cactaaacct tgcgcatgaa cctgagaaga ttcttcatcg gcttcattgg tgccgacatt
    12241 accaatatgg ggataagtaa gagtgacgat ttggcgggaa taggaaggat cagtgaggat
    12301 ttcttgataa ccggtcattg aagtattgaa aacgacttcc ccaaccgccg aacctgttgc
    12361 ccctatggcc cgaccgtgaa actgggttcc gtcttccaga accaatagcg ctgacttaat
    12421 caaaacaccc tccagagaat attcactcac tttatttgca tatcaattca ttcagtcagt
    12481 atgaagcaat gcaaatttgc ttacccgtgg atttctggca aac
//
LOCUS       DAJVBX010000137        12495 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.137, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000137 DAJVBX010000000
VERSION     DAJVBX010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 12495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12495
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.137"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(380..640)
                     /gene="iraP"
                     /locus_tag="OPV72_003165"
     CDS             complement(380..640)
                     /gene="iraP"
                     /locus_tag="OPV72_003165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001748986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-adapter protein IraP"
                     /protein_id="HCR9915387.1"
                     /translation="MKNLIAELLLKLAQKEEESKELVAQVEALEIIVTAMLRNMAQNE
                     QEMLIRQVEGALEGVKPDASVPDHDTELLRQYVKKLLRHPRH"
     gene            complement(937..2136)
                     /locus_tag="OPV72_003166"
     CDS             complement(937..2136)
                     /locus_tag="OPV72_003166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HCR9915388.1"
                     /translation="MESWKVNLISVWFGCFFTGLAISQILPFLPLYISQLGVSSHEAL
                     SMWSGLTFSITFLISAIVSPMWGSLADRKGRKLMLLRASLGMAIAILLQAFATHVWQL
                     FLLRGIMGLTSGYIPNAMALVASQVPRERSGWALSTLSTAQISGVIGGPLMGGFVADH
                     IGLRAVFLITAMLLVVSFLVTLFLIKEGVRPVIKKSERLSGKAVFASLPYPALVISLF
                     FTTMVIQLCNGSISPILALFIKSMMPDSNNIAFLSGLIASVPGISAPRLGKLGDRIGT
                     ERILMATLICAVLLFFAMSWVTTPFQLGLLRFLLGFADGAMLPAVQTLLVKYSSDQIT
                     GRIFGYNQSFMYLGNVVGPLMGATVSAMAGFRWVFIATAAIVLINIGQLTLALRHRRN
                     AQKAKGQ"
     gene            complement(2305..3018)
                     /locus_tag="OPV72_003167"
     CDS             complement(2305..3018)
                     /locus_tag="OPV72_003167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extensin family protein"
                     /protein_id="HCR9915389.1"
                     /translation="MFMGCENGGRVRGKGFLIIVLLGGIGGLGYRYLPSYYNPFAPLQ
                     LADPPGWITTFKLQRLTPSQCRELLTAANQQGLISSQPVADSAGECPLSHVVRVRDFG
                     QVKLSSSFLASCPLALRSALFVEQQAKPLTETWMQRRLTRIEHLGSYACRNIYHRPDA
                     RRSEHASAEALDVSGFQLSDGRKITVLRGWGREETGPWLRAMLNASCHYYGNGLGPDY
                     NAAHANHFHLGMRGYGVCR"
     gene            3096..4190
                     /gene="ddlA"
                     /locus_tag="OPV72_003168"
     CDS             3096..4190
                     /gene="ddlA"
                     /locus_tag="OPV72_003168"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HCR9915390.1"
                     /translation="MAKLRVGIVFGGKSAEHEVSLQSAKNIVDAIDKTRFDVVLLGID
                     KAGQWHVNDAENYLQNADDPAHIALRPSAISLAQVPGKHQHQLINAQNGQPLPTVDVI
                     FPIVHGTLGEDGSLQGMLRVANLPFVGSDVLSSAACMDKDVAKRLLRDAGLNIAPFIT
                     LTRTNRHAFSFAEVESRLGLPLFVKPANQGSSVGVSKVANEAQYQQAVALAFEFDHKV
                     VVEQGIKGREIECAVLGNDNPQASTCGEIVLNSEFYAYDTKYIDDNGAQVVVPAQIPS
                     EVNDKIRAIAIQAYQTLGCAGMARVDVFLTADNEVVINEINTLPGFTNISMYPKLWQA
                     SGLGYTDLISRLIELALERHTANNALKTTM"
     gene            complement(4216..4431)
                     /locus_tag="OPV72_003169"
     CDS             complement(4216..4431)
                     /locus_tag="OPV72_003169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2754 family protein"
                     /protein_id="HCR9915391.1"
                     /translation="MRLPVKIRRDWHYYAFSIGLIFILNGVVGLLGFEAKGWQTYGVG
                     LVTWIISFWLAGFIIRRREDDEVKDAR"
     gene            4699..5007
                     /locus_tag="OPV72_003170"
     CDS             4699..5007
                     /locus_tag="OPV72_003170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiY family protein"
                     /protein_id="HCR9915392.1"
                     /translation="MADFTLSKSLFSGKHRETSSTPGNIAYAIFVLFCFWAGAQLLNL
                     LVHAPGIYEHLMQVQDTGRPRVEIGLGVGTIFGLVPFLTGCLIFAVIAAFLRWRHRHQ
                     "
     gene            complement(5045..6139)
                     /gene="yaiW"
                     /locus_tag="OPV72_003171"
     CDS             complement(5045..6139)
                     /gene="yaiW"
                     /locus_tag="OPV72_003171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface-exposed outer membrane lipoprotein YaiW"
                     /protein_id="HCR9915393.1"
                     /translation="MSAASRLYPLPFLAVAILAGCSSQSGQPVSKGEKPVDVASVVRQ
                     KMPASVKDREAWAKDIATTFKSQGLAPTVENICSVLAVAQQESGYQADPVVPGLSKIA
                     WQEIDRRAERLHIPLFLVHTALKINSPNGKSYSERLDTVKTEKQLSAIFDDFINMVPM
                     GQTLFGSYNPVHTGGPMQVSIAFAEQHAKGYPWNMAGTVRQEVFTRRGGLWFGTYHLL
                     NYPANYSAPVFRFADFNAGWYASRNAAFQNAVSKASGVKLALDGDLIRYNSKEPGKTE
                     LAVRKLAGQLGMSEREIRSQLEKGDNLAFEKTALYKKVYKLAEAKTGKTLAREMLPGI
                     QLESPKITRKLTTAWFAKRVDERRARCMGR"
     gene            complement(6154..7374)
                     /gene="sbmA"
                     /locus_tag="OPV72_003172"
     CDS             complement(6154..7374)
                     /gene="sbmA"
                     /locus_tag="OPV72_003172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide antibiotic transporter SbmA"
                     /protein_id="HCR9915394.1"
                     /translation="MFKSFFPKPGPFFMSAFVWALIAVIFWQAGGGDWVARLVGASDE
                     VPISAARFWLLDYLIFYAYYLICVGLFATFWFIYSPHRWQYWSILGTSLIIFVTWFLV
                     EVGVAVNAWYAPFYDLIQTALNSPHKVTLGQFYHEVGVFLGIALIAVVIGVLNNFFVS
                     HYVFRWRTAMNEHYMAHWQYLRHIEGAAQRVQEDTMRFASTLENMGVSFINAIMTLIA
                     FLPVLVTLSAHVPNLPIVGHIPYGLVIAAIVWSLMGTGLLAVVGIKLSGLEFKNQRVE
                     AAYRKELVYGEDDASRATPPTVRELFSAVRHNYFRLYFHYMYFNIARILYLQVDNVFG
                     LFLLFPSIVAGTITLGLMTQITNVFGQVRGSFQYLINSWTTLVELMSIYKRLRSFERQ
                     LDGQPVQEVTHSFS"
     gene            7710..8867
                     /gene="ampH"
                     /locus_tag="OPV72_003173"
     CDS             7710..8867
                     /gene="ampH"
                     /locus_tag="OPV72_003173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine-
                     carboxypeptidase/endopeptidase AmpH"
                     /protein_id="HCR9915395.1"
                     /translation="MKRSLLFTAMLFAASLTSVQAAQPIADPVFASDIVDRYAEHIFY
                     GSGATGMALVVIDGNQRVFRSFGDTRPGNNVRPQLDSVIRIASLTKLMTSEMLVKLLD
                     QGTVKLNDPLSKYAPPGAHVPTYQGTPITLVNLATHTSALPREQPGGAAHRPVFVWPT
                     REQRWNWLSTATLKVAPGSQAAYSNLAFDLLADALATASGKPYTQLFEEKITRPLGMK
                     DTTFTPSPDQCKRLMVAEKGASPCNNTLAAIGSGGVYSTPGDMMRWMQQYLSSDFYHR
                     SHQADRMQTLIYQRAQLKKIIGMDVPGKADALGLGWVYMAPKDGRPGIIQKTGGGGGF
                     ITYMAMIPQYNIGAFVVVTRSPLTRFTNMSDGINDLVTELSGNKPIAIPAS"
     gene            complement(8912..9535)
                     /gene="iprA"
                     /locus_tag="OPV72_003174"
     CDS             complement(8912..9535)
                     /gene="iprA"
                     /locus_tag="OPV72_003174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogen peroxide resistance inhibitor IprA"
                     /protein_id="HCR9915396.1"
                     /translation="MLSLNKPLQEFNRLDKCLSKHGTRFEFVNDKEIICSPDESNTHT
                     FVILEGVVSLVRGDKVLIGIVQAPFIFGLADGVAKKEAQYKLIAESGCIGYRLSSSQT
                     LAIIEQNQLWREAFCWIVWKSQVLELRDKQLIGNNSYDQIRATLMTMIEWDEELRSRI
                     GVMNYIHQRTRVSRSVVAEVLAALRKGNYIEMNKGKLISINRLPSEY"
     gene            complement(9621..>12495)
                     /locus_tag="OPV72_003175"
     CDS             complement(9621..>12495)
                     /locus_tag="OPV72_003175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HCR9915397.1"
                     /translation="KKKLVVSQLALACTLAITSQANATTYDTFGYHDDAATVFGWDDT
                     NDHDYLTYGGYVYNTPASDSGYFDTKFTGDTVNGVISTYYLNHDYANDTANTLDVTNS
                     TIHGMITSYQMGYGQYVWTNGSDYTTHDWVDDDTFNLNISNSTIDDDFEAFYFTDTYL
                     DSDGKTVKTDYDKLVTAGLGTAITLDVESNINITNNSHVAGIALYQNDLGNSTYTTEA
                     HQWDNTINVANSTVTSGSWSEDEEQGHFGNSSEPSDYNGNGWNKDDVALAFVDDPYSN
                     YRMVNNVTFTDSQLLGDVVLESSWNYNFYSNGRLVDDSTTVYTNGGWADDDQNVDHLT
                     LTLNNTKWVGAAVNDSQSMDPVQFYDVDANSLDPDSTNYDAWGRVNSAASFQSGIFDV
                     SLNNGSEWDTTKTSVIDTLAVNSGSQVDVANGSNLTADTITLNGGSAMNIGEGGYVDT
                     DHLTVDTFSTVTLADDVSSAWSDDALYANTITVTHGGMLDIQTNNTNADSVIDTDTLE
                     LTSSNVADNNGNVYAGVFNIHSNDYTLNADLVNDRTWDTTQANYGYGVVAMNSDGHLT
                     INGNGDINNGDEADASSTTDNVVAATGNYKVRIDNATGAGSVADYKGNELIYVNDINT
                     DATFSAANKADLGAYTYQAKQEGNTVVLEQMELTDYANMALSIPSANTNIWNLEQDTV
                     GTRLTNARHGLADNGGAWVSYFGGNFNGDNGTINYDQDVNGIMVGVDTKVDGNNAKWI
                     VGAAAGFAKGDLSDRTGQVDQDSQSAYIYSSARFANNIFVDGNLSYSHFNNDLSANMS
                     DGTYVDGNTSSDAWGFGLKLGYDLKLGDAGYVTPYGSVSGLFQSGDDYQLSNDMKVDG
                     QSYDSMRYELGVDAGYTFTYSEDQALTPYFKLAYVYDDSNNDADVNGDSIDNGVEGFA
                     VRVGLGTQFSFTKNFSAYTDANYLGGGDVDQDWSANVGVKYTW"
BASE COUNT         3303 a         3203 c         2908 g         3081 t
ORIGIN      
        1 gtaaagtcac cagtaatgtt attttcatag caccatcctt ttgtcagtgt acacattaca
       61 cgttgtccct ttgggaaata tcccagggac tttatataag tctggctgtt actggcaaaa
      121 ataccacccg gcagtaaaag tattacttac cgttagcaat atatgtttta ttgattgaca
      181 aaccgtaggc taatgtgcaa ctcgattatc cacagtcaca ctggcaggat gcagaagaac
      241 agcgcataac gttacactgt tattaccata gccgcttcgt ttttattttg ctctgtatta
      301 accagaagaa aataaaaacg aagcggctat gttatttcat aaaagtaacg ttataacaac
      361 tgtgttgttt taaatacgat tagtgccggg ggtgtctcag caactttttt acatattggc
      421 gcagcaattc cgtatcgtga tcaggaacgc tggcatccgg ctttacgcct tcaagtgccc
      481 cctctacctg acgtatcaac atctcctgct cgttttgcgc catgttacgt aacattgctg
      541 tgacgataat ctctaacgct tctacctgag caaccagttc tttcgactct tcttcttttt
      601 gggctagctt aagcaacaac tctgctatga gatttttcat gaccatattt ccttattagt
      661 tccagggtga cgttatcact atgaagaacc actgcctaga ggctgaaagt actattttta
      721 tgatacagga agaactttac acaaataatt atcactgtcg ccgcagcgaa acgtttctca
      781 gaccgaaaac gagacgataa taaaccatca aaaaacaata atcacgctat atcataattt
      841 aaggttatgc catctataga aaaacttcac ggataaagag tatatctttt aatttaaacc
      901 atatcgtaac ggcagaagcg ccgttacgat gcaccgctat tggcctttcg ctttttgcgc
      961 gttacgccga tgacgtaacg ccagggtcag ttgtccaata ttgatcaaca cgatcgccgc
     1021 cgtagcgata aaaacccagc ggaaaccggc catcgccgat accgtcgcgc ccatcaacgg
     1081 cccaaccacg ttgcccaggt acataaatga ctggttgtag ccaaaaatac gtccggtaat
     1141 ttgatcgctg gagtatttca ccaataacgt ttgtacggcg ggtaacatcg cgccatcggc
     1201 aaagcctaac aagaaacgta acagccccag ctggaacggc gtggtgaccc aggacatcgc
     1261 gaagaaaagc agcactgcgc agataagcgt ggccatcaga attctttccg tgccgattct
     1321 gtcgccaagt tttcccaggc gaggcgcgga gataccgggc accgaggcga ttaacccgct
     1381 aagaaaggcg atgttattac tgtccggcat cattgatttg ataaacagcg ccaggattgg
     1441 actgatggaa ccattacaga gttgaatgac catcgtggta aaaaacaaac tgatcaccag
     1501 cgcaggataa ggtaacgacg caaaaacggc tttaccgctc aggcgttcgc ttttcttgat
     1561 gaccggacgc acgccttctt taattaaaaa tagcgtgacc agaaagctca ccaccaacag
     1621 catggcggta atcagaaata ccgcccgcag cccgatatga tccgcgacaa agccgcccat
     1681 taacggcccg ccgataacgc cgctgatctg cgcggtagaa agcgtactga gcgcccagcc
     1741 gctacgttcg cgcggtacct gagaggctac cagcgccatg gcattgggga tatagcctga
     1801 cgttaacccc atgattccgc gcagcaggaa aagttgccag acatgggtcg cgaatgcttg
     1861 cagtagaata gctatcgcca tcccgagcga cgcgcgcaat agcatcagtt tacgcccttt
     1921 acgatcggcg agactgcccc acatcggcga tacaatggcg gaaataagaa acgtgatgct
     1981 aaacgttaac ccggaccaca ttgataacgc ttcatgggaa gagacgccaa gctgggaaat
     2041 atacaggggt aaaaatggca ggatttggct gattgccagc ccggtaaaaa aacatccaaa
     2101 ccaaacggaa attagattaa ctttccagga ttccataaga ctcgtaacgg taagtagctg
     2161 aaaatacgcg ttagcttagc aagctctcat tttcctggtg gttccagagg tgcgatacgt
     2221 cacactttgc tattttgtct ccccgttcat catttttgtg aaacatatca cattatatag
     2281 ccgcgaaagg cagacgttta tgctttaacg acacacgccg tagccccgca ttccaagatg
     2341 aaaatggtta gcatgagcag cgttatagtc aggcccgagc ccattgccat aataatggca
     2401 actggcgttt aacatagcgc gtaaccaggg ccccgtctcc tcacgccccc agccgcgcag
     2461 gacagtgatt tttcggccat ctgatagttg aaacccgctg acatccagcg cttctgcgct
     2521 ggcatgttca ctgcgacgcg catccggacg gtgataaata ttacggcagg catagctgcc
     2581 cagatgttcg atgcgggtca ggcggcgctg catccacgtt tctgttaaag gttttgcctg
     2641 ctgttcgaca aacagcgcgg aacgcagcgc caacgggcag gaggctaaaa aactgctgct
     2701 cagttttacc tggccaaaat ctctgacgcg cacaacatgg gacaagggac attcaccagc
     2761 gctatccgca acaggttgtg atgaaattaa tccctgttga ttggccgccg tcaacagctc
     2821 ccggcactgc gacggcgtca ggcgctgtag tttgaaggta gtgatccagc ctggcggatc
     2881 ggcaagttgt agcggagcaa aaggattata ataagaggga agataacgat atcccagccc
     2941 gccaataccg cccaacagca caataatcag aaaaccctta cctctcacgc ggcctccgtt
     3001 ctcacatccc ataaacatta tggcagaagc ccgcgaaacc cgcgttttgt cgtggtaatg
     3061 tatacgcttt gcattcgatg gaatgggttt ttaagatggc gaaattgcgg gtaggaatag
     3121 tatttggcgg taagtcggcg gaacatgaag tgtctttgca atcagcgaaa aatatcgttg
     3181 atgcgatcga taaaacccgc ttcgacgtgg tgctgttagg gatagataag gcgggacaat
     3241 ggcatgttaa cgatgcggaa aattatttgc agaatgcaga cgatccggca catatcgcgc
     3301 tacgtccttc ggcaatcagt ctggcccagg tgcctggcaa acaccaacac caattgatta
     3361 acgctcagaa cgggcagccg ctaccgacgg tagatgttat ttttcctatc gtccacggta
     3421 cgctgggcga agacggctca ttgcagggga tgctgcgcgt cgcaaactta ccgtttgtcg
     3481 gttcagacgt gctgagctcc gcagcctgca tggataaaga cgtcgccaaa cgactgctac
     3541 gcgatgcagg actgaatatc gccccgttta ttacactcac ccgaacgaat cgtcacgcgt
     3601 ttagttttgc cgaggttgaa tcccgtctgg gactgccgct gttcgttaag cccgccaatc
     3661 agggctcttc ggtcggcgtc agtaaagtcg ctaacgaagc gcaatatcag caggcggtcg
     3721 cgctggcttt cgaattcgat cataaagtgg tggtggagca agggatcaaa gggcgcgaga
     3781 tcgaatgcgc cgtattaggt aacgataacc cacaggccag tacctgcggc gaaatcgtac
     3841 tgaacagcga attttacgcc tacgatacta agtatattga tgataatggc gcgcaagttg
     3901 tcgtgcctgc gcagatccct tccgaggtga atgacaagat ccgcgcgatc gcgatccagg
     3961 cttatcagac gctggggtgc gcgggtatgg cgcgtgtcga tgtcttctta acggcagaca
     4021 atgaggtcgt gattaacgag attaatacgc tgccaggttt taccaatatc agtatgtatc
     4081 caaaactctg gcaggcgagc ggattgggct ataccgattt gatcagccgc ctgattgagc
     4141 tggcgctgga acgccatacg gcgaataacg ccttaaaaac cacgatgtaa tagcgcacgc
     4201 ccgatagcgc aacgtttatc gggcgtcttt tacctcatca tcttcgcgcc ggcgaatgat
     4261 gaaccccgcc agccagaagc tgataatcca cgttaccagc ccaacgccat aggtttgcca
     4321 tcctttcgcc tcaaaaccca gcaatcctac gacgccattc aaaataaaga taaggccaat
     4381 agagaaggca tagtagtgcc agtcacgacg aatttttaca ggcaaacgca taacgactcc
     4441 gacgtattaa cagcaacaaa aacgtatttt tgcatacttc tggcgagcga gtctgtgggg
     4501 gatacggaat ttcttaaatg ttaattgatt ttgataaaag tgatcgtttt gtgacaacta
     4561 acaaaaattt acgcgatgga tacattccat atgtgaaatt accatgattc tgatattgac
     4621 aaacacaatg acctgtcaga cttcacagta agccgatggc ataacgccag atcgtagccg
     4681 atcatcctgg aggtctttat ggctgatttc actctctcaa aatcgctgtt cagcgggaag
     4741 catcgagaaa cctcctctac gcccggaaat attgcttacg ccatatttgt actgttttgc
     4801 ttctgggccg gagcgcaact cttaaacctg ctggttcatg cgccgggtat ctatgagcat
     4861 ctgatgcagg tacaggatac aggtcgacca cgggtagaga ttgggctggg cgtcgggacg
     4921 atttttggcc tggtgccctt cctcacgggc tgcctcattt ttgccgttat cgccgcgttt
     4981 ttacgctggc gtcaccgtca ccaataaacc ttagcgcgct ggagaaaata tcccagcgcg
     5041 aaatttatcg ccccatacac cgcgcccgcc gctcatcaac tcgtttagca aaccaggcgg
     5101 tcgtcagctt acgcgtgatc ttcggacttt ccagttgaat accgggcaac atttcccgcg
     5161 caagcgtctt gcccgttttg gcctcggcca gcttatagac tttcttgtag agcgccgttt
     5221 tttcaaacgc caggttatcg cctttctcca gttggctgcg aatttcacgc tcactcattc
     5281 ccaactgccc tgccagtttg cgcaccgcta actctgtttt gcccggttcc ttgctgttat
     5341 aacgaatcag atcgccatcc agcgccagtt ttaccccact ggctttactg acggcattct
     5401 ggaacgcagc gttacggctg gcgtaccatc ccgcgttgaa gtcggcgaag cggaaaacag
     5461 gcgcgctgta gttcgccggg taattcagca aatggtaggt tccaaaccac aatccgccac
     5521 ggcgcgtaaa gacctcctga cgtaccgtac ccgccatatt ccacggataa cctttcgcgt
     5581 gctgttcggc aaaggcaatg ctgacctgca tcgggccgcc cgtatgcacc gggttatatg
     5641 agccaaatag cgtctgcccc atagggacca tattgataaa gtcgtcaaaa atagcgctaa
     5701 gctgtttttc ggtttttacc gtgtccaggc gttcgctata gctcttgccg ttgggggagt
     5761 taattttcag cgcggtgtgc accagaaaca gcggaatgtg tagtcgttca gcgcggcgat
     5821 caatctcctg ccaggcgatt ttacttagcc ccggcacgac aggatccgcc tgataaccgg
     5881 actcctgctg ggcgacagcc agcaccgaac agatattttc taccgtcggc gccagcccct
     5941 ggctcttaaa cgttgtcgcg atatctttcg cccaggcctc tctgtctttg acactggccg
     6001 gcattttctg acgtactacg cttgccacgt cgacaggctt ctcgcccttg ctcaccggct
     6061 gcccggattg actactacag ccagccaata tggcgaccgc cagaaaaggc agaggataaa
     6121 gacgggacgc cgccgacata acgtttcctt ctgttagcta aaagagtggg tcacttcctg
     6181 aactggctga ccatccaact ggcgttcaaa gctacgtaaa cgtttataaa tagacatcag
     6241 ctccaccaga gtcgtccagg agttaatcaa atactggaac gaaccgcgca cctgaccaaa
     6301 cacgttggtg atttgcgtca tcagccccag cgtaatcgta ccggcaacaa tggaaggaaa
     6361 cagcaggaac aaaccgaaaa cgttatcgac ctgcaaatag agaatgcgcg cgatgttgaa
     6421 atacatatag tgaaagtaga gacggaagta gttatggcgc accgcgctaa acagttcacg
     6481 gacggtgggc ggcgtggcgc ggctggcgtc atcttcaccg tagaccagct ctttacgata
     6541 agctgcctcc actcgctgat ttttaaattc cagccccgac aatttgatcc cgacgaccgc
     6601 cagcaggccc gtccccatta atgaccagac tatggcggca atgaccaggc cgtaagggat
     6661 atgtcctacg atgggtaaat tcggcacatg cgctgacagg gtgaccaaca ccggcagaaa
     6721 ggcgataagc gtcatgatgg cattgataaa actcacgccc atgttctcca gtgtagaggc
     6781 aaaacgcatg gtatcttcct gcacacgctg ggcggcccct tcgatatggc gcaggtactg
     6841 ccagtgcgcc atatagtgct cattcattgc ggtacgccag cgaaatacat agtggctgac
     6901 aaagaagttg ttcagcacgc cgatcaccac ggcgataagc gcaataccga gaaacacccc
     6961 cacttcatga taaaattgac caagagtgac cttgtgcggc gagttgagcg ccgtttgaat
     7021 caaatcatag aatggcgcgt accaggcgtt aaccgcgacg ccaacctcca ccaaaaacca
     7081 ggtgacaaaa ataatgagcg aggtgccaag tatcgaccag tactgccagc ggtgcgggct
     7141 atagatgaac cagaacgttg caaataatcc cacgcaaatc aggtaataag cataaaaaat
     7201 cagatagtcc agcaaccaga agcgcgctgc gctgataggc acttcatcgg atgcccctac
     7261 aagtcgcgcc acccaatctc ctcctcccgc ctgccagaaa atgacagcga tcagcgccca
     7321 aacaaacgcc gacatgaaaa acggccctgg ctttgggaaa aaagatttaa acatcatgct
     7381 ctcctgctaa cttcttatct ttattacggc tgctgtgacg gcggcaatag cacgccatgc
     7441 ccacggctaa accaggcatt gtgacctacg ttgtgacgct tagttcgcat ttctgctcaa
     7501 cagaattgtt tcgacgagtt tcatactcag caggcacgct gacgctatca ggttatcaca
     7561 agcgctttat cacaaaagta aacattctcc atcacgaaaa cccgccgtta cgttttttca
     7621 cccacttttt tctctttaac gttttgcaat gtgccgccgg gtagtataaa tacgcataac
     7681 caccgttatt tcacttatgg acatcaccgt tgaaacgtag tctgcttttt actgccatgc
     7741 tgtttgcggc atcacttact tctgtccagg cggctcagcc gattgccgat ccggtttttg
     7801 cctctgatat cgttgatcgt tatgccgagc atatctttta tggtagcggc gccacgggca
     7861 tggcgctggt ggtgatcgac ggcaatcaac gcgtgtttcg tagtttcggt gacaccagac
     7921 cgggcaataa tgttcgtcca cagcttgact cggtcattcg tatcgcttct ctcaccaagc
     7981 tcatgaccag tgaaatgttg gtaaaattgc tcgatcaggg aacggtaaaa ttaaacgatc
     8041 cgctcagcaa atatgcgcct cccggcgcgc atgtcccgac gtatcaaggc acgccgatta
     8101 cgttggtcaa cttagcgacc cacaccagcg cgcttccgcg agaacagccc ggcggcgcgg
     8161 cgcatcgtcc ggtatttgtc tggccaaccc gcgaacaacg ctggaactgg ctctccacag
     8221 caacgttaaa agtcgcgccc ggttcacagg cggcctattc caatctggcg ttcgacctgt
     8281 tagccgacgc gctggcgacc gcctccggca aaccttatac gcaactgttt gaagaaaaga
     8341 ttacccgccc gctgggaatg aaagacacca cgtttacccc ctctcccgat cagtgtaagc
     8401 gtctgatggt ggcagagaaa ggcgcaagcc cctgtaataa tacgctggct gccattggca
     8461 gcggcggagt ctattctacg ccaggagata tgatgcgctg gatgcaacag tatctgtcgt
     8521 cagatttcta tcaccgtagc catcaggccg atcgtatgca aacgttgatt tatcagcgcg
     8581 cacagttaaa gaaaatcatc gggatggacg taccgggtaa agccgacgcg ctcggtctgg
     8641 gctgggtcta tatggcgcca aaagacggac gtcctggcat tatccagaaa acgggaggcg
     8701 gcggcggttt tattacctat atggcgatga tcccacaata taatattggc gcttttgtgg
     8761 tcgtaacccg ttcccccctc acccgtttta ccaatatgag cgacgggatt aacgatttgg
     8821 ttactgagct aagcggcaat aaaccgattg ctattcctgc atcctgagtc gtcgcgcctc
     8881 gcgctatatc agacgaggcg cgacattttt gttaatattc ggagggcaaa cggttaatac
     8941 tgatcaattt gcctttattc atttcaatgt aattaccctt acgcagggcc gcgagaactt
     9001 ccgccaccac cgatcgcgat acgcgcgttc gttgatgtat ataattcata acaccaatac
     9061 gtgagcgaag ttcttcatcc cactcaatca ttgtcattaa cgtcgcacga atctggtcgt
     9121 aagaattatt accaatgagc tgcttgtcac gaagctccag tacctgactt ttccatacta
     9181 tccaacagaa ggcttcacgc cacagttggt tctgctcaat gatggcgaga gtttgtgatg
     9241 atgagaggcg ataaccgatg caaccgctct ccgcaattaa tttatattgt gcctcttttt
     9301 tcgccacgcc atcggctaag ccaaaaataa aaggggcctg cacaatacca ataagaactt
     9361 tatcaccccg aactaacgaa acaaccccct ctaaaataac aaaggtatgg gtattacttt
     9421 catcaggtga acagataatc tctttatcgt taacaaactc gaaacgcgta ccatgcttag
     9481 aaaggcattt atcgagtctg ttgaattcct gtagtggctt gtttaaagat aacatatgca
     9541 ttccttgcaa taatgcccgt caagtccttg acgggcattt ttcagtttaa attactttta
     9601 tttctcctga gagaaaatga ttaccaggta tatttaacac caacgtttgc agaccagtct
     9661 tgatcaacat caccgccgcc gaggtagtta gcatcggtgt aggcgctgaa gttcttcgtg
     9721 aagctgaact gagtacccag accaacacgt accgcaaaac cttctacgcc gttgtcgata
     9781 gagtcgccgt ttacgtcagc atcgttgttg gagtcgtcgt aaacgtaagc cagtttgaag
     9841 tacggggtca gcgcctgatc ttcgctgtaa gtgaaggtat aacctgcatc tacaccgagt
     9901 tcataacgca tgctgtcgta agactgaccg tcaactttca tgtcgttgct cagctggtag
     9961 tcgtcgccgg actggaacag accggatacg ctgccgtaag gcgttacgta gcctgcatca
    10021 cccagcttca gatcataacc cagtttcaag ccgaagcccc aggcgtcaga agaggtgttg
    10081 ccgtcaacgt aagtaccgtc gctcatgtta gcagacaaat cgttgttgaa gtgagagtag
    10141 cttaagttac cgtcaacaaa gatgttgttt gcgaaacgag cggaagagta gatgtaggca
    10201 gactggctgt cctgatccac ctgaccggta cgatcgctca gatcgccttt cgcgaagcct
    10261 gctgccgcac caacgatcca cttagcgttg ttaccgtcaa ctttggtatc aacaccgacc
    10321 atgatgccat taacatcctg atcgtagtta atggtgccgt tgtcgccgtt gaagttaccg
    10381 ccgaagtagc ttacccatgc gccgccgtta tccgccaggc catgacgagc gttggtcaga
    10441 cgagtaccaa cggtgtcttg ttccaggttc cagatattgg tgttcgcaga aggaatgctc
    10501 agcgccatgt tagcgtagtc ggtcagttcc atctgttcca gcacgacagt gttgccttcc
    10561 tgcttagcct gataggtgta agcacccagg tcagctttgt ttgctgcaga gaaggtagcg
    10621 tcggtgttta tgtcattgac ataaatcagc tcgttacctt tgtaatccgc aacagaaccg
    10681 gcaccagtag cgttgtcgat gcgcacttta taattaccag tggccgctac aacgttgtca
    10741 gtggtgctac ttgcatcagc ctcgtcacca ttgttgatat cgccgttacc gttgatagtc
    10801 agatgaccat cagagttcat cgcgacaacg ccgtaaccgt agttagcctg agtggtatcc
    10861 caggtacggt cgttcaccaa atcggcattt agggtatagt cattgctatg aatgttgaac
    10921 acaccagcat aaacattgcc attattatcc gcaacgttac tgctagtcag ttctaacgta
    10981 tcagtatcaa tgacgctatc tgcgtttgta ttgttggttt gaatatctaa cataccaccg
    11041 tgagttacgg taatagtatt agcatacagt gcatcatcac tccatgcact gctgacatca
    11101 tcagccaaag taactgtact gaaagtatca acggtcaggt gatcagtatc aacgtagcca
    11161 ccttccccga tgttcatagc tgaaccaccg tttagagtaa tggtatcagc ggttaaattg
    11221 gagccattag cgacatcaac ctgagagccg ctatttactg ctaaggtatc tattacagat
    11281 gtttttgtgg tatcccactc agatccatta ttcaagctga cgtcaaagat accgctctgg
    11341 aaggaagcag cactattaac acgtccccag gcatcataat tagtcgagtc tggatctaag
    11401 ctattggcat caacatcata gaattgcact ggatccattg actgtgaatc attaaccgcc
    11461 gcaccaaccc atttagtgtt attcagggtc aatgtcaggt gatcaacgtt ttgatcatca
    11521 tctgcccaac caccattcgt atagacagta gtggaatcat cgactaaacg gccattagaa
    11581 tagaaattat aattccagga gctctcaagg acgacatccc ccagtaactg cgagtcggta
    11641 aacgtaacgt tgtttaccat acggtaattt gaataaggat cgtcaacaaa agctaaagca
    11701 acatcatctt tattccaacc attgccatta taatcgcttg gttcacttga attgccaaaa
    11761 tggccttgtt cctcatcttc ggaccaggag cctgaagtta cagttgaatt cgctacgtta
    11821 atagtgttat cccactgatg tgcttcggtt gtatatgttg aattgccaag atcattttgg
    11881 taaagagcaa taccagccac atgagaattg ttagtaatat taatattact ttcaacatca
    11941 agggttatag cagtgcctaa accagcagta accaatttgt cataatcggt tttgactgtt
    12001 tttccatcag aatcgagata ggtatcagtg aagtaaaacg cctcaaagtc atcatcgatt
    12061 gtagaattag aaatgtttag attaaaagta tcatcatcaa cccaatcatg ggtcgtataa
    12121 tcactaccgt tagtccaaac atattgaccg tagcccatct ggtaagaagt aatcatacca
    12181 tgaatggttg agttggtaac atccaatgta ttcgcagtat cattggcgta atcatgattc
    12241 agataataag ttgaaataac gccatttaca gtgtcaccag taaattttgt atcaaaatag
    12301 ccgctatcac tagctggggt gttgtagaca taaccaccat aagttagata gtcatggtcg
    12361 ttggtatcat cccagccaaa aacagtggcc gcatcgtcat ggtacccaaa agtatcgtat
    12421 gtagtagcat tcgcctgaga agtgattgcc agagtgcaag ccaatgctaa ttgtgagact
    12481 acaagtttct ttttc
//
LOCUS       DAJVBX010000138        12441 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.138, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000138 DAJVBX010000000
VERSION     DAJVBX010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 12441)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12441)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12441
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.138"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            181..672
                     /gene="napF"
                     /locus_tag="OPV72_003176"
     CDS             181..672
                     /gene="napF"
                     /locus_tag="OPV72_003176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-type protein NapF"
                     /protein_id="HCR9915398.1"
                     /translation="MVDLSRRSMLTGSWRNASNGILPPWARETTYFLAHCLRCDACIQ
                     ACEADILQRGTGGYPSVNFKRGECSFCYACAQACPESLFLPRRTRAWDLIFTLTENCL
                     ARQSVECHRCLDSCEPMAITFRPTLSGIYQPQLDSQACNGCGACVAICPVSAIKAENH
                     HAH"
     gene            662..925
                     /gene="napD"
                     /locus_tag="OPV72_003177"
     CDS             662..925
                     /gene="napD"
                     /locus_tag="OPV72_003177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperone NapD"
                     /protein_id="HCR9915399.1"
                     /translation="MRTNWQVCSLVVQAKSQNIAAIGTQLNTLPGCEVALSDVESGQL
                     IVVAEADQSETLMQTIESVRNVEGVLAVSLVYHQQDEQGEETP"
     gene            922..3408
                     /gene="napA"
                     /locus_tag="OPV72_003178"
     CDS             922..3408
                     /gene="napA"
                     /locus_tag="OPV72_003178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase catalytic subunit NapA"
                     /protein_id="HCR9915400.1"
                     /translation="MKLSRRSFMKANAVAAAAAAAGLSVPGVARAVVGQQEAIKWDKA
                     PCRFCGTGCGVLVGTQQGRVVACQGDPDAPVNRGLNCIKGYFLPKIMYGKDRLTQPML
                     RMKDGSYHKDGEFTPVSWEQAFDVMEEKFKTALKEKGPEAIGMFGSGQWTIWEGYAAA
                     KLFKAGFRSNNIDPNARHCMASAVVGFMRTFGMDEPMGCYDDIEQADAFVLWGSNMAE
                     MHPILWSRITNRRLSDPNVKVAVLSTFQHRSFELADNGIVFTPQSDLVILNYIANYII
                     QNNAVNQDFFTKHVNLRKGATDIGYGLRPTHPLEKAAKNPGSDASEPMSFDEYKAFVA
                     EYTLDKTAEMTGVPKDQLEQLAQLYADPNKRVISYWTMGFNQHTRGVWANNLVYNLHL
                     LTGKISQPGCGPFSLTGQPSACGTAREVGTFSHRLPADMVVTNEKHRDICEKHWQIPA
                     GTIPAKVGLHAVAQDRALKDGKLNVYWVMCNNNMQAGPNINEDRMPGWRDPRNFIIVS
                     DPYPTVSALSADLILPTAMWVEKEGAYGNAERRTQFWRQQIKAPGEAKSDLWQLVQFS
                     RRFKTEEVWPEALLAQKPELRGKTLYDVLFATPAVSKFPLSELKEDQLNDESRELGFY
                     LQKGLFEEYAWFGRGHGHDLAPFDDYHNARGLRWPVVEGKETQWRYSEGNDPYVKAGE
                     GYKFYGKPDGKAVIFALPFEPAAESPDNEYDLWLSTGRVLEHWHTGSMTRRVPELHRA
                     FPEAVVFIHPLDAKARDLRRGDKVKVSSRRGEVISIVETRGRNRPPQGLVYMPFFDAA
                     QLVNNLTLDATDPLSKETDFKKCAVKLAKV"
     gene            3415..4110
                     /gene="napG"
                     /locus_tag="OPV72_003179"
     CDS             3415..4110
                     /gene="napG"
                     /locus_tag="OPV72_003179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-type protein NapG"
                     /protein_id="HCR9915401.1"
                     /translation="MSRTAKPQNGRRRFLRDVVRTAGGLAAVGVALGLQQQTARATGV
                     RLRPPGALNENVFASACVRCGQCVQACPYDTLKLATLASGLSAGTPYFVARDIPCEMC
                     EDIPCAKVCPSGALNKDIASIDDSRMGLAVLLDQENCLNFQGLRCDVCYRECPKIDEA
                     ITLELDRNMRTGKHARFLPTVHSDACTGCGKCEKVCVLEQPAIKVLPLSLAKGELGHH
                     YRFGWLEGKDGKS"
     gene            4097..4966
                     /gene="napH"
                     /locus_tag="OPV72_003180"
     CDS             4097..4966
                     /gene="napH"
                     /locus_tag="OPV72_003180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinol dehydrogenase ferredoxin subunit NapH"
                     /protein_id="HCR9915402.1"
                     /translation="MANRKRDAGREARAKKGWWRSHRWLVLRRISQFMVLGMFLSGPW
                     LGFWVLHGNYSSSLLFDTLPLTDPLITLESLASGHLPATVALTGAVIIAVLYALAGKR
                     LFCSWVCPLNPVTDLANWMRRKFDLNQSATIPRHIRYVLLVVVLIGSALTGTLLWEWI
                     NPVSLLGRSLIMGFSSGALLIIALFLFDLLVVEHGWCGHICPMGALYGVLGSKGVVTV
                     TAKKREKCNRCMDCFHVCPEPHVLRAPVLDEQSPAQVTHRDCMTCGRCVDVCSEDVFT
                     ITIHNIIRDASRR"
     gene            5082..5531
                     /gene="napB"
                     /locus_tag="OPV72_003181"
     CDS             5082..5531
                     /gene="napB"
                     /locus_tag="OPV72_003181"
                     /EC_number="1.9.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase cytochrome c-type subunit"
                     /protein_id="HCR9915403.1"
                     /translation="MKSHDLMKALCQWMATLALVVSGAVWAANGVDLSQSPEVSGTQE
                     GAIRMPKEQERMPLNYVNQPPMIPHSVEGYQVTTNTNRCLQCHGVESYRTTGAPRISP
                     THFMDSDGKVSGNVAPRRYFCLQCHVPQSDTAPIIDNTFTPSQGYGK"
     gene            5541..6143
                     /gene="napC"
                     /locus_tag="OPV72_003182"
     CDS             5541..6143
                     /gene="napC"
                     /locus_tag="OPV72_003182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c-type protein NapC"
                     /protein_id="HCR9915404.1"
                     /translation="MENSNRKLGWIKRVWRWWRSPSRLALGTLLLIGFIGGVIFWGGF
                     NTGMEKANTEEFCISCHEMRNTVYEEYMETVHYNNRSGVRATCPDCHVPHEWGPKMIR
                     KIKASKELYAKVFGLIDTPQKFEAHRLTMAQNEWRRMKDNNSQECRNCHNFDFMDLTA
                     QKGVAAKMHDQAVKDGQTCIDCHKGIAHKLPDMRDVKPGF"
     gene            6164..6781
                     /gene="ccmA"
                     /locus_tag="OPV72_003183"
     CDS             6164..6781
                     /gene="ccmA"
                     /locus_tag="OPV72_003183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c biogenesis heme-transporting ATPase
                     CcmA"
                     /protein_id="HCR9915405.1"
                     /translation="MLEARDLYCERDERTLFRGLSFTVEAGEWVQVTGGNGAGKTTLL
                     RLLTGLARPDGGEVYWQGEPLRRVRDSFHRSLLWIGHQPGIKTRLTARENLHFFHPGD
                     GARLPEALAQAGLAGFEDVPVAQLSAGQQRRVALARLWLTRAALWVLDEPFTAIDVNG
                     VARLTRRMAAHTAQGGMVILTTHQPLPGAADTVRRLALTGGGAGL"
     gene            6778..7437
                     /gene="ccmB"
                     /locus_tag="OPV72_003184"
     CDS             6778..7437
                     /gene="ccmB"
                     /locus_tag="OPV72_003184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme exporter protein CcmB"
                     /protein_id="HCR9915406.1"
                     /translation="MMWRVFCLELRVAFRHGADIAGPLWFFLMVITLFPLSVGPQPQL
                     LARIAPGIIQVAALLASLLALERLFRDDLQDGSLEQLMLLPVPLPAVVLAKVLAHWAV
                     TGLPLMMLSPLVALLLGMDVYGWKIMALTLLLGTPALGFLAAPGVGLTAGLRRGGVLL
                     GILVLPLSVPVLIFATAAMDAASMHLPVDGYLAVLGALLAGSATLSPFATAAALRIST
                     Q"
     gene            7489..8226
                     /locus_tag="OPV72_003185"
     CDS             7489..8226
                     /locus_tag="OPV72_003185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter permease"
                     /protein_id="HCR9915407.1"
                     /translation="MWKTLHQLAAPPRLYQICGRLVPWLAAAGIIVLATGWVRGFGFA
                     PADYQQGESYRIMYLHVPAAIWSMGIYAAMAVAAFTGLVWQMKMASLAVAAMAPVGAV
                     YTFIALVTGAAWGKPMWGTWWVWDARLTSELVLLFLYAGVIALWHAFDDRKMAGRAAG
                     ILVLVGVVNLPVIHYSVEWWNTLHQGSTRMQLSIDPAMRSPLRWAIAGFLLLFMTLAL
                     MRMRNLILLMEKRRPWVSELILKRGHR"
     gene            8223..8435
                     /gene="ccmD"
                     /locus_tag="OPV72_003186"
     CDS             8223..8435
                     /gene="ccmD"
                     /locus_tag="OPV72_003186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme exporter protein CcmD"
                     /protein_id="HCR9915408.1"
                     /translation="MSPAFSSWSDFFAMGGYAFFVWLAVAMTVAPLALLALHTVLQRR
                     AILRGVAQQRAREARMRAAQAQQEAA"
     gene            8432..8911
                     /gene="ccmE"
                     /locus_tag="OPV72_003187"
     CDS             8432..8911
                     /gene="ccmE"
                     /locus_tag="OPV72_003187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c maturation protein CcmE"
                     /protein_id="HCR9915409.1"
                     /translation="MNLRRKNRLWVVCAVLAGLALTTALVLYALRANIDLFYTPGEIL
                     YGKRETQQLPAVGQRLRVGGMVMPGSVRRDPDSLKVNFSLYDAEGSVTVSYEGILPDL
                     FREGQGVVVQGTLEKGNHVLAHEVLAKHDENYTPPEVEKAMQENHRRPQRADKDTSS"
     gene            8908..10839
                     /locus_tag="OPV72_003188"
     CDS             8908..10839
                     /locus_tag="OPV72_003188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme lyase CcmF/NrfE family subunit"
                     /protein_id="HCR9915410.1"
                     /translation="MMPEYGHALLCLALGVALLLSVYPLWGVARGDARMMASAGVFAW
                     LLFICVAGAFFVLVHAFVVNDFTVAYVAGNSNTQLPVWYRVAATWGAHEGSLLLWVLL
                     MSGWTLAVAVFSRQVPADIVARVLAVMGMVCAGFLAFILFTSGPFARTLPAFPVEGRD
                     LNPLLQDPGLIFHPPLLYMGYVGFSVAFAFAIAALLSGRLDSAFTRFARPWTLAAWVF
                     LTLGIVLGSAWAYYELGWGGWWFWDPVENASFMPWLAGTALLHSLAVTEQRAGFKAWT
                     LLLSICAFSLCLLGTFLVRSGVLVSVHAFASDPARGMFILAFMVLVTGGSLLLFAVRG
                     HRVRSRVNNALWSRESLLLGNNVLLMAAMLVVLLGTLLPLVHKQLGLGSISVGEPFFN
                     TMFTWLMVPFALLLGVGPLVRWGRDRPRNIRKLLLTALVSTLVLSVLLPWLLEDRIIA
                     MTAVGMAMACWIAVLAVAEAVQRVSRGTKTSLSYWGMVAAHLGLAVTITGIAFSQNYS
                     VERDVRMRAGDSVTIHDYRFTFREVRDITGPNYRGGVALIGVTRHGEPEAVLHAEKRL
                     YNTSRMVMTEAAIDGGLTRDLYAALGEELDNGAWAVRLYYKPFVRWIWAGGLLMALGG
                     LLCLADPRYRRRKPLPEAG"
     gene            10836..11393
                     /gene="dsbE"
                     /locus_tag="OPV72_003189"
     CDS             10836..11393
                     /gene="dsbE"
                     /locus_tag="OPV72_003189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbE"
                     /protein_id="HCR9915411.1"
                     /translation="MKRNVLLLPLLIFLLIAAALLWQLARNAQGDDPTNLESALTGKP
                     VPAFRLESLETPGQYYQAEVLTQGKPVLLNVWATWCPTCRAEHQYLNRLAAQGIRVVG
                     LNYKDDRAKAVAWLKELGNPYALSLSDSDGMLGLDLGVYGAPETFLIDGRGIIRYRHA
                     GDLNARVWESELKPLWDRYSREAAQ"
     gene            11390..12433
                     /locus_tag="OPV72_003190"
     CDS             11390..12433
                     /locus_tag="OPV72_003190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c-type biogenesis protein CcmH"
                     /protein_id="HCR9915412.1"
                     /translation="MRLLPGMVMLMLALVISGSARATTDVMPFKDEAQEQQFRQLTEQ
                     LRCPKCQNNSIADSNAMIATDMRRRVYDLMQEGKSRQEIIDYMVARYGNFVTYDPPLT
                     PLTVLLWVLPLAAIVAGGWIIVARTRRRVRLRREPLPADTPVCGARAGWGVYVPGAVI
                     ALAVGAGSYALTGSYPQVRAWQQATAQTPGLLARALDPQAQPLNEEEMARLALGLRTR
                     LQNDAGNVEGWLMLGRTGMVLGNAGTATGAYANAYRLDPENRDAALGYAEALTRSSDP
                     EDNRRGGELLRQLVSRDHTDIRVLSLYAFSAFEQQRFGEAVAAWEMMLKLLPAGDARR
                     AVIERSIRLAQEK"
BASE COUNT         2264 a         3500 c         4198 g         2479 t
ORIGIN      
        1 acgtttacgg gtctttaccc ggcactcttt tgatccggca acagcattta cctctatcgg
       61 ggtatgcatc tcttacacat cctgaaatat cttatttaca aaaataacta ctcataaatt
      121 gtacggtttt tattggcatt cactccctat ggaagcgtgt cgttatggaa gggcgatatc
      181 atggttgatt tatcccgtcg aagcatgttg accggcagtt ggcgcaacgc cagcaatggg
      241 attcttccgc cgtgggccag agaaacgacc tattttctcg cacattgtct gcgttgcgac
      301 gcctgcatcc aggcgtgtga ggccgacatc ctgcagcgag ggacgggggg atatccgagc
      361 gtaaatttca aacggggcga gtgcagcttt tgttatgcct gtgcgcaggc ctgtcccgaa
      421 tctctctttc ttccgcgccg caccagggcc tgggatctga tttttacact cacggaaaac
      481 tgcctcgcca ggcagtcggt tgaatgccat cgttgcctgg acagttgtga acctatggcc
      541 attacctttc gtcccacgtt atccggtatt taccagccgc agcttgactc gcaggcctgt
      601 aacggatgcg gggcgtgtgt ggctatctgt cccgtgtcag ccatcaaagc ggagaaccac
      661 catgcgcact aactggcagg tctgtagcct ggtcgtgcag gccaaaagtc agaacatcgc
      721 cgccattggc acacagttga acacgttgcc gggttgcgaa gtcgcgttaa gcgacgttga
      781 aagcgggcaa ctgatcgtgg tggcggaagc agaccagagt gaaacgctga tgcaaacaat
      841 tgagtcagta cgcaatgtcg agggcgtgct ggcggtgtcg ctggtttatc accagcagga
      901 tgagcaaggt gaggaaacac catgaaactc agtcgtcgta gctttatgaa agctaacgcc
      961 gttgcggccg ctgcggcggc tgccggtctg agcgtgccgg gcgtcgcccg cgccgttgtc
     1021 gggcagcagg aagctatcaa atgggataaa gcgccgtgcc gtttttgcgg aacgggttgc
     1081 ggtgtgttgg tgggaacgca gcagggccgt gtggtcgcct gccagggcga ccccgacgcg
     1141 ccggtcaacc gtggtctgaa ctgcattaaa ggctacttcc tgcccaaaat catgtacggt
     1201 aaagatcgtc tgacgcagcc gatgctgcgc atgaaagacg gcagctatca caaagacggc
     1261 gagtttacgc cggtgagctg ggaacaggcc ttcgatgtga tggaagagaa gtttaaaacc
     1321 gccctgaaag agaaaggacc agaagcgatc ggcatgtttg gatcgggtca atggaccatc
     1381 tgggaaggct atgccgccgc gaaactgttc aaggctggtt tccgctctaa caacatcgac
     1441 ccgaacgcgc gtcactgcat ggcctcggcg gtggtgggct ttatgcgcac ctttggcatg
     1501 gatgaaccga tgggctgcta cgacgatatt gagcaggccg atgcgtttgt gctgtggggg
     1561 tccaacatgg cggagatgca cccgatttta tggtcgcgca tcactaaccg ccgtttgtcc
     1621 gacccgaatg tgaaagttgc tgtcctctcc accttccagc accgtagctt tgagctggcg
     1681 gacaacggta ttgtctttac cccgcaaagc gatctggtga tccttaacta tatcgcgaat
     1741 tacattattc agaacaacgc ggtaaatcag gatttcttca caaagcatgt gaatctgcgt
     1801 aaaggggcga cggatatcgg ctacggctta cgcccgacgc acccgctgga aaaagcggcg
     1861 aagaatccgg gctccgacgc ttccgagccg atgagcttcg acgagtataa agccttcgtg
     1921 gcggaatata cgttggacaa gactgctgaa atgaccggcg tgccgaaaga tcaactggaa
     1981 cagttggcac agctctacgc cgatccgaat aagcgcgtga tctcttactg gacgatgggt
     2041 tttaaccagc atacccgcgg cgtgtgggcg aataacctgg tttacaacct ccatctgctg
     2101 accggaaaaa tctcccagcc tggctgcggt cctttctcgc tgaccggcca gccttccgcc
     2161 tgcggtacgg cgcgtgaagt gggaaccttc tcacaccgtc tgcccgcaga catggtcgtg
     2221 acgaacgaaa aacaccgtga tatctgcgaa aaacactggc agatccccgc tggcactatc
     2281 ccggcaaaag tgggtttaca tgcggtggcg caggatcgcg cgttgaaaga cggcaagctg
     2341 aacgtctact gggtaatgtg taataacaat atgcaggccg ggccgaacat caatgaagat
     2401 cggatgccgg gctggcgcga tccgcgtaac tttatcattg tctccgatcc ttacccgacg
     2461 gtgagcgcgc tgtctgctga tctgatcctg ccgaccgcca tgtgggttga gaaagaaggc
     2521 gcttacggca acgccgaacg ccgcacgcag ttctggcgtc agcaaattaa agcgccgggc
     2581 gaagccaaat ccgacctctg gcaactggtg cagttctccc gtcgttttaa aaccgaggag
     2641 gtctggccgg aggcgttgtt ggcccagaag ccggagctgc gcggcaaaac gctgtatgac
     2701 gttctattcg ccacgcctgc ggtcagcaaa ttcccgctga gcgagctgaa agaagatcag
     2761 ttaaacgatg agtctcgtga gctgggcttc tatctgcaaa aagggctatt tgaagaatac
     2821 gcctggtttg gacgtggcca cggtcacgat ctggcgccgt tcgacgatta ccacaacgcg
     2881 cgcggtctgc gctggccggt cgtcgaaggc aaagagacgc aatggcgtta cagcgaaggc
     2941 aacgacccgt atgtaaaagc gggggaaggg tacaaattct acggtaaacc ggatggcaaa
     3001 gcggtgatct tcgcgctgcc atttgaaccc gcggcggagt cgccggacaa cgagtacgat
     3061 ctgtggcttt ccaccggtcg cgtactggaa cactggcata ccggcagtat gacgcgccgc
     3121 gtgcctgaat tgcatcgcgc cttcccggaa gcggtggtct ttattcaccc gctggatgcg
     3181 aaagcgcgcg atctgcgtcg tggggataag gttaaagtgt cgtcccgccg cggcgaagtg
     3241 atttcgattg tcgaaacgcg tggacgtaac cgtccgccgc agggactggt gtatatgccg
     3301 ttcttcgatg ccgctcagct agtgaacaac ctgacgctgg atgcgacgga cccgctctct
     3361 aaagagacgg acttcaagaa gtgcgccgtt aagctggcga aggtgtaacg cgttatgtcc
     3421 cgtacagcga aaccccaaaa tggccgccgc cgctttctgc gtgatgttgt gcgcactgcg
     3481 ggcgggctgg cggcggttgg cgtggcgctg ggcttgcaac agcaaaccgc gcgcgcaacg
     3541 ggcgtgcggc tgcgtccgcc tggcgcgctg aatgaaaatg ttttcgccag cgcctgtgtg
     3601 cgctgcgggc agtgcgttca ggcgtgtcca tacgacacgc taaaactggc gacgctggcc
     3661 tccgggctat cggcaggtac gccctatttc gtcgctcgcg acatcccctg cgaaatgtgt
     3721 gaagacattc cgtgcgccaa agtctgcccc agcggggcgc tgaataaaga tatcgcctcc
     3781 attgatgact cgcgcatggg gctggcggtg ctgctggatc aggaaaactg cctcaacttt
     3841 caggggctgc gctgcgacgt ttgctaccgc gaatgcccga aaatcgatga ggccatcacg
     3901 ctggagctgg atcgcaacat gcgcactggc aaacatgcgc gctttctgcc caccgtacac
     3961 agcgacgcct gtaccggctg cggcaaatgc gaaaaagtct gcgtactgga gcaaccagcg
     4021 ataaaagtgt tgccgttgtc attggcgaaa ggggagttag gacaccatta ccgcttcggc
     4081 tggctggagg ggaaagatgg caaatcgtaa acgcgacgcc gggcgagaag cgcgggcgaa
     4141 aaaaggctgg tggcgtagcc accgttggct ggtgttacgc cgtatcagcc agtttatggt
     4201 gctggggatg tttctcagcg gcccgtggct gggcttttgg gttttgcatg gcaactacag
     4261 cagtagtttg ctgttcgata ccctcccgtt gaccgatccg ctgattaccc tggaaagtct
     4321 cgccagtgga catcttcccg ctaccgtggc gctgacggga gcagtgatta tcgctgtgct
     4381 gtatgcgctg gcgggaaagc gattattttg cagttgggtt tgcccgctaa accccgttac
     4441 cgatttggct aactggatgc gcaggaaatt tgacctgaac cagtcggcga cgattccacg
     4501 ccatatacgg tatgtccttc tggtggtggt gttaatcggt tcggcgttga ccggcacgct
     4561 gctgtgggaa tggattaatc ccgtgtcgct gttaggtcgt agtctgatta tgggatttag
     4621 tagcggcgcg ttgctgatta ttgctttgtt tttatttgat ttattagtcg ttgagcacgg
     4681 ttggtgcggt catatttgcc cgatgggcgc gctgtatggc gtgctgggca gtaaaggcgt
     4741 agtgaccgtg acggccaaaa aacgtgagaa atgtaatcgc tgtatggatt gttttcatgt
     4801 ttgcccggaa ccgcatgtgc tacgtgcgcc ggtgctggat gagcaaagcc cggcgcaggt
     4861 cactcaccgc gactgcatga cctgcggtcg ctgcgtggat gtctgttctg aggatgtttt
     4921 tacaataacg atacacaaca tcattcggga tgcatcgcgg cggtaagcga ggaaatcccc
     4981 gggagcatag ataacgatgt gactgggatt ttcgagcgca gccaacaaag aggcagctcg
     5041 aaggatgaag tgtaaatgcg atggagttcg ggagcgaaac aatgaaaagc catgacctga
     5101 tgaaagcgct gtgtcaatgg atggccacgc ttgccctggt ggtaagtggt gcggtttggg
     5161 cggcaaacgg agtggatctg agccagtcgc cggaagtatc cgggacgcag gaaggggcga
     5221 ttcgtatgcc gaaagagcag gaacgtatgc cgctaaatta cgtcaaccag ccgccgatga
     5281 tcccgcacag cgtcgagggc taccaggtga cgaccaatac caaccgctgt ctgcaatgcc
     5341 acggcgtgga aagttatcgt acgacgggcg cgccgcgtat cagtccgacg cactttatgg
     5401 acagcgacgg taaagtgtcg ggcaacgtcg cgccgcgtcg ttatttctgc ctgcagtgcc
     5461 acgtaccgca gtctgatacc gcgccgatta tcgacaatac ctttaccccc tcgcaaggtt
     5521 acgggaaata agaggtcatt atggaaaatt ctaaccgtaa acttggctgg ataaagcgcg
     5581 tctggcgatg gtggcgcagc cccagccgcc tggcgctggg gacgctgctg ttaatcggtt
     5641 ttatcggcgg cgtcatcttc tggggcggct tcaataccgg aatggaaaag gctaataccg
     5701 aagagttttg tattagctgc catgaaatgc gcaacacggt gtatgaggag tatatggaaa
     5761 ccgtccacta caacaaccgt agtggcgttc gcgccacctg tcctgactgc catgtgccgc
     5821 atgagtgggg gccgaagatg atccgtaaga tcaaagccag taaagaactg tacgcgaagg
     5881 tatttgggct gatagataca ccgcagaaat ttgaagctca tcgcctgaca atggcacaaa
     5941 atgagtggcg gcgcatgaaa gacaacaact cgcaggaatg ccgtaactgc cacaatttcg
     6001 actttatgga tctgaccgcg caaaaaggcg tcgcggcgaa aatgcacgat caggcggtaa
     6061 aagatggaca gacctgtatc gattgccaca aagggatcgc gcataaactg ccggatatgc
     6121 gtgatgttaa accaggtttc tgacaggacg ttgatgagtg ggaatgcttg aagccagaga
     6181 tctgtactgc gagcgggacg agaggacgct gtttcgcggg ctgtcgttca ccgtggaggc
     6241 cggggagtgg gtgcaggtca ccggcggcaa cggcgccgga aaaaccaccc tgctgcgcct
     6301 gctgaccggg ctggcgcgcc cggacggcgg ggaggtgtac tggcagggcg agcccctgcg
     6361 ccgcgtgcgc gacagcttcc atcgcagcct gctgtggata gggcaccagc cggggataaa
     6421 aacccgcctg acggcgcggg agaacctgca ctttttccac cccggtgacg gcgcgcgtct
     6481 cccggaggcg ctggcgcagg ccgggctggc gggatttgag gacgtgccgg tcgctcagct
     6541 ctcggccggg cagcagcgcc gggtggcgct ggcccgcctg tggctgaccc gcgccgcgct
     6601 gtgggtgctc gacgagccgt tcaccgccat tgacgttaac ggcgtggcgc gcctcacccg
     6661 gcggatggcg gcgcacacgg cgcagggcgg gatggtcatc ctcaccaccc accagccgct
     6721 gccgggggcc gcggacaccg tccgccgcct ggcgctgacc ggcggggggg ccgggctgtg
     6781 atgtggcgtg tcttctgtct cgagctgcgc gtggcgttcc gccacggcgc ggacatcgcc
     6841 ggcccgctgt ggttcttcct gatggtcatc accctgtttc cgttaagcgt cgggccgcag
     6901 ccgcagctgc tggcgcgtat cgcgccgggc atcatccagg tggcggcgct gctggcctcg
     6961 ctgctggcgc tggagcggct gtttcgcgac gacctgcagg acggcagcct ggagcagctg
     7021 atgctgctgc cggtgccgct gccggcggtg gtgctggcga aggtgctggc ccactgggcg
     7081 gtgaccggcc tgccgctgat gatgctctcc ccgctggtgg cgctgctgct ggggatggac
     7141 gtgtacggct ggaaaatcat ggcgctgacg ctgctgctcg gcacgccggc gctggggttt
     7201 ctcgccgcgc cgggcgtcgg gctgacggcc ggcctgcggc gcggcggcgt cctgctgggc
     7261 attctggtgc tgccgctgag tgtcccggtg ctgattttcg ccaccgcggc gatggacgcg
     7321 gcatcgatgc atttacccgt tgacggctat ctggcggtgc tgggggcgct gctggcgggc
     7381 agcgcgacgt taagcccgtt cgccaccgcg gcggcgctgc gcatcagtac gcagtagcgc
     7441 cccggcacga cggacatttt actggtttca ggaggtcagg tgacgactat gtggaaaacc
     7501 cttcatcagc tggcggcgcc gccccggctg tatcagattt gcggcaggct tgtgccgtgg
     7561 ctggcggcag ccggcatcat tgtgctggcc acgggctggg tccggggctt tggtttcgcc
     7621 ccggcggact accagcaggg ggagagctac cgcattatgt acctgcatgt cccggcggcc
     7681 atctggtcga tgggtatcta tgcggcgatg gcggtggcgg cgttcaccgg gctggtctgg
     7741 cagatgaaaa tggccagcct tgccgtcgcg gcgatggcgc cggtgggggc ggtgtacacc
     7801 ttcatcgcgc tggtcaccgg cgcggcgtgg ggcaaaccga tgtggggcac ctggtgggtg
     7861 tgggacgcgc gcctgacctc ggagctggtg ctgctgtttc tctatgccgg ggtcatcgcc
     7921 ctgtggcacg cctttgacga ccgtaaaatg gccgggcgcg cggcgggcat tctggtgctg
     7981 gtcggcgtgg tgaacctgcc ggttatccac tattccgtcg agtggtggaa caccctgcac
     8041 cagggctcga cgcggatgca gctgagtatc gacccggcga tgcgctcgcc gctgcgctgg
     8101 gccatcgccg gcttcctgct gctctttatg acgctggcgc tgatgcggat gcgcaacctg
     8161 attttactga tggaaaaacg ccgcccgtgg gtgagcgaac tgatactgaa aagggggcac
     8221 cggtgagtcc ggcattttca tcgtggagcg attttttcgc catgggcggg tacgcctttt
     8281 ttgtctggct ggcggtggcg atgaccgtgg cgccgctggc gctgctggcg ctgcacacgg
     8341 tgctgcagcg ccgggccatt ctgcgcggcg tggcgcagca gcgggcgcgc gaggcgcgga
     8401 tgcgtgccgc acaggcgcaa caggaggccg cgtgaacctg cgacgtaaaa accggctatg
     8461 ggtggtctgc gcggtgctgg cgggcctggc gctgaccacc gccctggtcc tgtacgcgct
     8521 gcgcgcgaat atcgacctgt tctatacccc cggcgaaatc ctctacggca agcgcgagac
     8581 gcagcagctg ccggcggtgg gccagcgcct gcgcgtcggc gggatggtga tgcccggcag
     8641 cgtcaggcgc gacccggact cgctgaaggt gaacttcagc ctctacgacg ccgaagggtc
     8701 ggtgacggtg agctatgagg ggatactgcc ggacctgttc cgcgaggggc agggggtggt
     8761 ggtgcagggc accctggaga agggcaacca cgtcctggcg cacgaggtgc tggccaagca
     8821 tgacgagaac tacaccccgc cggaagtgga aaaggcgatg caggaaaacc accgccgccc
     8881 gcaacgcgct gataaggaca cttcatcatg atgcctgaat acggccacgc actgctgtgc
     8941 ctggcgctcg gcgtggcgct gctgctgtcc gtttacccgc tgtggggcgt ggcgcgcggc
     9001 gacgcgcgga tgatggcgtc ggccggggtg ttcgcctggc tgctgttcat ctgcgtggcg
     9061 ggcgcgtttt tcgtgctggt gcacgccttt gtggttaacg acttcaccgt ggcctatgtc
     9121 gccggcaact cgaacacgca gctgccggtg tggtaccggg tggccgccac ctggggggcg
     9181 cacgagggct cgctgctgct gtgggtgctg ctgatgagcg gctggaccct ggcggtggcg
     9241 gtgttcagcc ggcaggtgcc ggcggatatc gtcgcccggg tgctggcggt gatggggatg
     9301 gtctgcgccg gttttctggc gttcatcctg ttcacctccg gcccgtttgc ccgcacgctg
     9361 ccggcctttc cggtggaggg gcgcgacctg aacccgctgc tgcaggaccc ggggctgatt
     9421 ttccacccgc cgctgctgta catgggctat gtcggcttct cggtggcctt cgccttcgcc
     9481 atcgccgcgc tgctgagcgg gcgtctggac agcgcgttca cccgttttgc ccgcccgtgg
     9541 acgctggcgg cgtgggtgtt cctgacgctg ggcatcgtgc tcggctcggc gtgggcctac
     9601 tacgagctgg gctggggcgg ctggtggttc tgggacccgg tggagaacgc ctcctttatg
     9661 ccgtggctgg cgggcaccgc cctgctgcac tcgctggcgg tcaccgaaca gcgcgccggc
     9721 tttaaggcgt ggacgctgct gttgtccatc tgcgccttct cgctgtgcct gctgggcacc
     9781 ttcctggtgc gctccggggt gctggtgtcg gtgcacgcct tcgcctccga cccggcgcgc
     9841 ggaatgttta tcctcgcctt tatggtgctg gtcaccggcg gctcgctgct gctgttcgcc
     9901 gtgcgcgggc acagggtgcg ttcgcgggtg aacaacgcgc tgtggtcgcg tgagtcgctg
     9961 ctgctcggca acaacgtcct gctgatggcc gccatgctgg tggtgctgct gggtaccctg
    10021 ctgccgctgg tgcacaaaca gctggggctg ggcagcattt cggtggggga gccgttcttt
    10081 aacaccatgt tcacctggct gatggtcccc tttgccctgc tgctgggggt ggggccactg
    10141 gtgcgctggg gccgggaccg gccgcgtaac atcaggaaac tgctgctcac cgccctggtc
    10201 tccaccctgg tgctgtcggt acttttgcca tggctgctgg aagatagaat catcgccatg
    10261 acggcggtgg ggatggcgat ggcctgctgg attgcggtgc tggcggtggc cgaagccgta
    10321 cagcgcgtgt cccgcggcac gaaaacctct ctcagctact ggggaatggt ggcggcgcac
    10381 ctcgggctgg cggtgacgat taccggtatc gccttcagcc agaattacag cgtggagcgt
    10441 gacgtgcgga tgcgggcggg cgacagcgtg accattcacg actaccgctt caccttccgg
    10501 gaggtgcggg acatcaccgg gcccaactac cgcggcgggg tggccctcat cggggtgacg
    10561 cgccacggcg agccggaggc ggtgctgcac gcggagaaac ggctctacaa caccagccgg
    10621 atggtgatga ccgaggcggc gattgacggc gggctgaccc gcgacctgta cgccgcgctc
    10681 ggggaggagc tggacaacgg cgcgtgggcc gtgcgcctgt actacaaacc gtttgtccgc
    10741 tggatatggg ccggggggct gctgatggcg ctgggcgggc tgctgtgcct ggcggacccg
    10801 cgctaccgcc gccgtaaacc attgccggag gccggatgaa acgcaacgta ctgttattac
    10861 cgctgctgat ttttctgctg attgccgcgg cgctgctgtg gcagctggcg cgcaacgcgc
    10921 agggggatga cccgacgaat ctcgaatcgg cgctgaccgg aaagccggtg ccggcgtttc
    10981 gcctggaatc gctggagacg ccgggtcagt actatcaggc ggaggtgctg acgcagggga
    11041 aaccggtgct gcttaacgtc tgggccacct ggtgcccgac ctgccgcgcc gagcatcagt
    11101 acctgaaccg gctggccgcg cagggtatcc gggtggtggg gctgaactat aaggacgacc
    11161 gggcgaaggc ggtggcctgg ttaaaggaac tgggcaaccc gtatgcgctg agtttatcgg
    11221 acagcgacgg gatgctgggg ctggacctgg gcgtgtacgg cgcgccggaa accttcctca
    11281 tcgacggcag ggggattatc cgctaccgcc atgcgggcga tttgaatgcc cgggtatggg
    11341 aaagtgaact gaaaccgctg tgggacagat acagccggga ggcggcgcaa tgagactgtt
    11401 accgggcatg gtgatgctga tgctggcgct ggttatctcc gggtcagcgc gggcgaccac
    11461 cgacgtgatg ccgtttaaag atgaagcgca ggagcagcag ttccgccagc tcacggagca
    11521 gctgcgctgc ccgaaatgcc agaacaacag cattgcggac tcgaacgcga tgatagccac
    11581 cgacatgcgc cgcagggtgt atgacctgat gcaggagggg aagagccgcc aggaaatcat
    11641 cgattacatg gtggcgcgct acggcaactt cgtcacctac gacccgccgc tgaccccgct
    11701 gacggtgctg ctgtgggtgc tgccgctggc cgccatcgtg gcgggcgggt ggataatcgt
    11761 cgcccggacg cgccggcggg tgcgcctgcg ccgggagccg ctgccggcgg acaccccggt
    11821 ttgcggcgcg cgcgccgggt ggggcgttta cgtgccgggg gccgtcattg cgctggcggt
    11881 cggcgccggc agctacgccc tgaccggcag ctatccgcag gtgagggcct ggcagcaggc
    11941 aacggcgcag acgcccgggc tgctggcgcg ggcgctggac ccgcaggcgc agccgctgaa
    12001 tgaggaggag atggcgcggc tggcgctggg gctgcgcacc cgcctgcaga atgatgccgg
    12061 caatgttgag ggctggctca tgctggggcg caccggtatg gtactgggta atgccggtac
    12121 cgccaccggg gcgtatgcga acgcttaccg tctggacccg gaaaaccgcg atgcggcgct
    12181 gggctacgcg gaggcgctga cgcgctcgtc cgacccggag gataaccgcc gcggcgggga
    12241 actgctgcgt cagctggtga gccgcgacca cacggatatc cgggtgttaa gcctgtatgc
    12301 gttcagcgcc tttgagcagc agcgctttgg cgaggcggtg gcggcctggg agatgatgct
    12361 gaagctgctg ccggcgggtg acgcccggcg ggcggtgata gagcgcagta tccggctggc
    12421 gcaggagaaa taagaccctg a
//
LOCUS       DAJVBX010000139        12393 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.139, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000139 DAJVBX010000000
VERSION     DAJVBX010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 12393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12393
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.139"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..1232)
                     /locus_tag="OPV72_003191"
     CDS             complement(<1..1232)
                     /locus_tag="OPV72_003191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR9915413.1"
                     /translation="MSETKKSGIDYWKQIVVVMSLGWVAIWIYRTVLTPIYPEIQASL
                     DNVSNAEIGAIASFYFFAYCSMQIPCGILVDKFGQKIMLMAGFTLFIIGTLCIAKANG
                     LAMIYTGSLMAGGGCASFFSSAYSLSSANVPQARRALANAIINSGSAIGMGIGLIGSS
                     VLVKNMSMAWQNVLYIVAAILVIMLCVFTLVIRGKAKSDSAQAEKQTQTVTEDEKRAP
                     LFSGLLCSVYFLYFCTCYGYYLIVTWLPSYLQTERGFDGGAIGLASALVAVVGVPGAL
                     FFSHLSDKFRNSKVKVILGLEIVAAAMLAFTVLSPNTTMLMVSLTLYGLLGKMAVDPI
                     LISFVSEQASAKSLGRAFSLFNFFGMSSAVVAPTLTGFISDVTGSKEISFVISACLVV
                     TGTLIFAAVTLYKKKATQR"
     gene            complement(1298..2176)
                     /gene="glxR"
                     /locus_tag="OPV72_003192"
     CDS             complement(1298..2176)
                     /gene="glxR"
                     /locus_tag="OPV72_003192"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HCR9915414.1"
                     /translation="MKLGFIGLGIMGSPMAINLARAGHQLHVTTIGPVADELLSLGAV
                     NVETARQVTEFADIIFIMVPDTPQVEEVLFGEHGCAKTSLQGKTIVDMSSISPIGTKR
                     FAQRVNEMDADYLDAPVSGGEIGAREGTLSIMVGGEQKVFDRVKPLFDILGKNITLVG
                     GNGDGQTCKVANQIIVALNIEAVSEALVFASKAGADPVRVRQALMGGFASSRILEVHG
                     ERMINRTFEPGFKIALHQKDLNLALQSAKALALNLPNTATCQELFNTCAANGGSQLDH
                     SAMVQALELMANHKLS"
     gene            complement(2277..3053)
                     /gene="hyi"
                     /locus_tag="OPV72_003193"
     CDS             complement(2277..3053)
                     /gene="hyi"
                     /locus_tag="OPV72_003193"
                     /EC_number="5.3.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxypyruvate isomerase"
                     /protein_id="HCR9915415.1"
                     /translation="MLRFSANLSMLFTEYDFLERFDKAAQSGFRGVEFMFPYDDDIEV
                     LKRKLRDNNLEHTLHNLPAGDWAAGERGIACIPGREEEFRDGVAAAIRYARALGNKKI
                     NCLVGKTPSGFSATEIYDTLVENLRYAANMLAKEDILLLIEPINHFDMPGFHLTGTQQ
                     ALVLIKDIGSDNIKIQYDIYHMQRMEGELTQTMTAWADKIGHLQIADNPRRGEPGTGE
                     INYDFIFNVIKQSDYDGWVGCEYKPLTTAEAGLSWINQYR"
     gene            complement(3066..4847)
                     /gene="gcl"
                     /locus_tag="OPV72_003194"
     CDS             complement(3066..4847)
                     /gene="gcl"
                     /locus_tag="OPV72_003194"
                     /EC_number="4.1.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate carboligase"
                     /protein_id="HCR9915416.1"
                     /translation="MAKMRAVDAAMYVLEKEGITTAFGVPGAAINPFYSAMRKHGGIR
                     HILARHVEGASHMAEGYTRAAAGNIGVCLGTSGPAGTDMITALYSASADSIPILCITG
                     QAPRARLHKEDFQAVDIEAIAKPVSKMAVTVREAALVPRVLQQAFHLMRSGRPGPVLV
                     DLPFDVQVAEIEFDPDMYEPLPVYKPAASRVQIEKALEMLIQSERPVIVAGGGVINAD
                     AAPLLQQFAELINVPVIPTLMGWGCTLDDHPLMAGMVGLQTAHRYGNATLLASDMVFG
                     IGNRFANRHTGSVEKYTQGRKIIHIDIEPTQIGRVLCPDLGIVSDAKAALTLLIDVAQ
                     EMQKAGRLPCRKTWVDECQQRKRTLLRKTHFDNVPVKPQRVYEEMNKAFGRDVCYVTT
                     IGLSQIAAAQMLHVFKDRHWINCGQAGPLGWTIPAALGVCAADPQRNVVAISGDFDFQ
                     FLIEELAVGAQFNIPYIHVLVNNAYLGLIRQSQRAFDMDYCVQLAFENINSSEVNGYG
                     VDHVKVAEGLGCKAIRVFKPEDIAPAFEQAKALMAQYRVPVVVEVILERVTNISMGDE
                     LDNVTEFEEVADSAKDAPTETCFMKYE"
     gene            complement(4932..5750)
                     /gene="allR"
                     /locus_tag="OPV72_003195"
     CDS             complement(4932..5750)
                     /gene="allR"
                     /locus_tag="OPV72_003195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional repressor AllR"
                     /protein_id="HCR9915417.1"
                     /translation="MTEVRRRGRPGQAEPTAQKGAQALERGIAILQYLERSGGSSSVS
                     DISGSLDLPLSTTFRLLKVLQAADFVYQDSQLGWWHIGLGVFNVGSAYIHNRDVLSVA
                     GPFMHRLMLLSGETVNVAIRNGNEAVLIGQKECKSMVRMCAPLGSRLPLHASGAGKAL
                     LYPLTEEELVGIVVNTGLRRFTPTTLVDLPILLKNLERAREQGYTVDQEEHVVGLNCI
                     ASAIYDDAGSVVAAISISGPASRLTEDRFISQGELVRDTAKDISTALGLKPPVA"
     gene            complement(5829..6310)
                     /gene="allA"
                     /locus_tag="OPV72_003196"
                     /pseudo
     CDS             complement(5829..6310)
                     /gene="allA"
                     /locus_tag="OPV72_003196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459510.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ureidoglycolate lyase"
     gene            6537..7463
                     /gene="allS"
                     /locus_tag="OPV72_003197"
     CDS             6537..7463
                     /gene="allS"
                     /locus_tag="OPV72_003197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator AllS"
                     /protein_id="HCR9915418.1"
                     /translation="MFDPETLRTFISVAETGSFSKAAERLCKTTATTSYRIKLLEENT
                     GVGLFFRTTRSVSLTAAGSHLLSQAKDWLAWLDSMPDELRQVNDGVERQVNIVVNNLL
                     YSPQAVASLLSWLNARYPFTQFHFSRQIYMGVWDSLLYEGFSLAIGVTGTEPLANTFM
                     LDPLGSVQWRFVMSADHPLAHVSGPLTEAQLRRFPAINIEDSARTLTKRVAWRLPGQK
                     EIIVPDMETKIAAHLAGVGIGFVPQPLCQTLIDKNELVSCTIPTMRPPSPLSLAWHKF
                     GGGKAVEDIVKLFTQRQPEIAGFLSIFNTVRC"
     gene            7533..8627
                     /gene="mnmH"
                     /locus_tag="OPV72_003198"
     CDS             7533..8627
                     /gene="mnmH"
                     /locus_tag="OPV72_003198"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-selenouridine(34) synthase MnmH"
                     /protein_id="HCR9915419.1"
                     /translation="MQDRQKAQDYRALLLADTPLIDVRAPIEFEQGAMPGAINLPLMM
                     DDERAAVGTCYKRQGADAALALGHRLVCGDIRQQRLEAWKAAYQRFPNGYLCCARGGQ
                     RSHIVQRWLQETGIDCPLIEGGYKALRQTAIQATWQLAQKPILLIGGCTGSGKTQLVR
                     QQPNGVDLEGLARHRGSSFGRTLKPQLSQASFENKLAVELLKINARQTLKRWVLEDEG
                     RTIGANHLPECLRERMAQAPIAVVEDPFALRLERLREEYFIRMHHDFTHAYGDGAGWQ
                     AYSEYLHHGLFAIRRRLGLQRFAELTDTLDRALAEQLSSGSTDGHMAWLVPLLNEYYD
                     PMYRYQLEKKAANIVFRGTWQDVANWLKAQ"
     gene            complement(8666..9325)
                     /locus_tag="OPV72_003199"
     CDS             complement(8666..9325)
                     /locus_tag="OPV72_003199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR9915420.1"
                     /translation="MDDLLPDLTLAFNETFQMLSISTVLAILGGLPLGFLIFVTDRHL
                     FWQNRFIYLVASVLVNIIRSVPFVILLVLLLPLTQLLLGNTIGPIAASVPLSVAAIAF
                     YARLVDSALREVDKGIIEAALAFGASPMRIICTVLLPEASAGLLRGLTITLVSLIGYS
                     AMAGIVGGGGVGDLAIRYGYYRYETEVMVVTVVALIVLVQVVQMLGDWLAKRADKRDR
                     H"
     gene            complement(9318..10334)
                     /gene="sfbB"
                     /locus_tag="OPV72_003200"
     CDS             complement(9318..10334)
                     /gene="sfbB"
                     /locus_tag="OPV72_003200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence-associated ABC transporter ATP-binding
                     protein SfbB"
                     /protein_id="HCR9915421.1"
                     /translation="MIEIEKVCVDFTAGRGTPTRAVDDVSLHIAAGEIFGIVGTSGAG
                     KSTLLRTLNALTRPSQGRVNVNGVEISALDGKALRQARQRIGMIFQHFNLMHTRTVAK
                     NVAFSLKAAGWERSKIAPRVAEILTLVGLADKANCFPVQLSGGQKQRVGIARAIANHP
                     DVLLCDEPTSALDLETSATILALLRQINAQLGITIVLITHEMNVIKSICDRVAVMSGG
                     KVVESGEVFDVFAHPQHAFTQQLVSHTLNLTLPERLREHLPGQLLKILFIGDSAEQPV
                     LSEVAIKFGVAVNILHGKIEYIGERALGILVVQLTAPHNPTAVAAAVEHIRQRTAQVE
                     VIRG"
     gene            complement(10371..11201)
                     /locus_tag="OPV72_003201"
     CDS             complement(10371..11201)
                     /locus_tag="OPV72_003201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HCR9915422.1"
                     /translation="MGLRQSLRIAASTLLLACGLQFAHADGSPQTIVFGVAPGPYGDM
                     VKQAIAPTLKEKGYKVVVREFSDYVQPNMALANGSIDANLFQHTLYFDKFTADKGLKL
                     SKLIVVPTAGMGFYSRKINSLDALKKGDIITLSNDPTNLARGLRFLQSLGLITIKHNI
                     DPTKASERDIASNPKGLVFKPLEAAQLPRTLDGVTGALVNGNFAVAAGLDLSSAIKQE
                     HLDENLKNIIAVRSEDADKPFAKDIVEAVKSPAYRAVIDDPKNIYSAFQKPEWMTATP
                     "
     gene            complement(11458..>12393)
                     /locus_tag="OPV72_003202"
     CDS             complement(11458..>12393)
                     /locus_tag="OPV72_003202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin"
                     /protein_id="HCR9915423.1"
                     /translation="YKRNGFDGGTRFRFAADYYLFDDISWISYYELGVNIPAVFDWDN
                     HYAKGTTDTTRRMLYTGFKSATWGTLTFGQQNSIYYDVVGVKTDIWDYDMIGQAPGNG
                     INGDYDGSYRTRKSLKYKKSIGNVDLYASYLFSDDYNANNGLNYKRKGGGSLGADYHL
                     TDDLTWGTAWNYTRAEMRGNGNKTYDQNIVGTALSWTPENWTIAAGGGWYQNFMTTKK
                     VSVNDYFAGDAWGLEYFVGYAFPIGQYAVKAIQPYFMGDRIEYVNGRDYLRTDNGVGI
                     TFQLDYGFRVDYEHVFTSSTDNLGDMNLVRLRYDF"
BASE COUNT         3083 a         3412 c         2962 g         2936 t
ORIGIN      
        1 cgttgcgttg ctttcttttt atataatgtg acagcagcaa agatcagcgt tccggtaacc
       61 actaaacatg ctgaaatcac aaaactgatc tccttcgacc ccgttacatc cgaaataaat
      121 ccggtcaacg ttggggcgac aaccgctgaa ctcatgccaa agaaattaaa aaggctgaaa
      181 gctcttccca gactttttgc cgaagcctgt tcagatacaa aggagatcag gatcgggtct
      241 actgccattt tccctagcaa gccgtatagc gtcaggctga ccatcagcat cgtggtattc
      301 ggggacaaaa ccgtaaacgc caacattgcc gccgccacaa tttccagacc gagaataacc
      361 ttaactttac tgttacggaa tttatctgac agatggctaa aaaataacgc ccccggtacg
      421 ccaaccaccg ccaccagagc tgatgccagc ccgatagctc cgccatcaaa tcctctttca
      481 gtctggagat aagaaggcag ccaggtcact atcaaataat aaccgtagca ggtacagaaa
      541 tagaggaagt aaacgctaca caataaacca gagaataaag gcgcgcgttt ctcatcttcc
      601 gtaacggttt gggtttgctt ttccgcttgc gcagagtcgc ttttggcttt accacgaatg
      661 accagcgtaa agacgcacag cataattact aatatcgcgg ccacgatata cagtacattt
      721 tgccaggcca tgctcatgtt ttttactaat acgctggaac cgattaagcc aatccccatc
      781 cctatagccg acccgctgtt gataatcgcg ttggctaatg cccgacgggc ctgcggcacg
      841 tttgccgaag agagtgaata agccgaacta aagaaagaag cgcatcctcc gcctgccatt
      901 agcgaccctg tatagatcat ggccaggcca ttggctttcg cgatacagag tgtaccaata
      961 ataaaaagcg taaatccggc catcagcatg attttttgac cgaatttatc gaccaatatt
     1021 ccgcaaggga tttgcatact gcagtaagca aaaaagtaaa aacttgcaat ggcgcctatt
     1081 tctgcattac ttacattgtc taaagatgcc tgaatttctg gataaattgg cgtaagcacg
     1141 gtgcgataga tccaaatcgc tacccagccc agactcatta cgacaacaat ttgtttccag
     1201 taatcaatcc cggatttttt agtttcactc atgttcttca cctttacaga gtgttccttg
     1261 tgaacaggta tcgctgcagc cgcagcgata cacataatta ggacaattta tgattggcca
     1321 ttaattccag cgcctgtacc attgccgaat gatcaagctg gctcccgcca tttgccgcac
     1381 aggtattgaa taattcctgg caggtcgccg tattcggtaa attcagcgcc agcgcttttg
     1441 cgctttgcaa tgcaagatta aggtctttct gatgaagcgc gattttgaaa ccaggctcga
     1501 acgtccggtt gatcatccgc tcgccgtgaa cttccagaat gcgtgaagag gcgaacccgc
     1561 ccattaacgc ctggcgcacg cgtaccggat cggcgcctgc ttttgaagca aacactaagg
     1621 cttcagaaac cgcttcaata ttcagcgcaa caataatttg gttagccacc ttacaggttt
     1681 gcccatcccc attgccgccc accagggtga tattttttcc caggatgtca aagagcggtt
     1741 taacgcggtc aaagactttc tgctcgccgc cgaccataat cgacagagtg ccttcacgcg
     1801 ccccgatttc tcccccggaa accggggcat ccaggtaatc agcgtccatt tcattaacgc
     1861 gctgggcaaa acgtttggtt ccgataggag aaatagaact catatcgacg atggtttttc
     1921 cctgaagcga tgttttggcg caaccgtgtt cgccaaataa cacctcttca acctgcggcg
     1981 tatccggcac cattatgaag atgatgtctg cgaattcagt cacctgacgt gcagtctcaa
     2041 catttaccgc ccccagcgag agcagttcgt ccgcgactgg accaatagtc gtaacgtgta
     2101 attgatgacc ggcgcgtgcc aaattgatag ccattggcga gcccataatt cccaggccaa
     2161 taaatcccag tttcatatac aacctctttt attgctttcg gtgtttccag attcaggcaa
     2221 cacaatcccc ttccaacaca gtggaaaaaa aagcgctgcc cgaattattc tgcgttttaa
     2281 cggtactgat taatccacga taatcccgct tccgcggtag tcagtggttt atattcacat
     2341 ccaacccagc catcataatc agactgttta atgacattaa aaataaagtc ataattgatt
     2401 tccccggtcc ccggctcgcc gcgacgcggg ttatcagcaa tctgtaaatg gcctatttta
     2461 tcggcccatg ccgtcatggt ttgcgttaat tccccttcca tgcgttgcat gtgataaata
     2521 tcatactgaa ttttgatatt atcgctgccg atatccttaa ttaatactaa cgcctgttga
     2581 gtgccggtga gatggaatcc cggcatatca aagtgattaa taggttcgat aagtaataaa
     2641 atgtcttctt tcgccagcat atttgccgca tagcgcaggt tttcgaccaa cgtgtcgtag
     2701 atctccgttg cggagaatcc tgacggcgtt ttacccacca gacaatttat tttcttattg
     2761 cctaacgcgc gtgcatagcg gattgcggcc gctacgccat cgcgaaactc ttcttcgcgc
     2821 ccaggaatac aggcaattcc acgttcgcca gccgcccagt cgccagccgg taaattatgt
     2881 aacgtatgtt ccagattatt atccctgagc ttacgtttta acacttcgat gtcgtcatcg
     2941 tagggaaaca tgaattccac gccgcgaaat cccgactgcg ccgctttatc aaagcgttcc
     3001 aggaaatcat attccgtaaa cagcatagaa agattggcag agaaacgtaa catcgattac
     3061 ctcccttact catatttcat aaaacaggtt tctgttggcg catctttcgc actatccgca
     3121 acctcttcaa actcggttac gttatccagt tcgtcgccca tggaaatatt ggttacgcgt
     3181 tccagaatga cttccaccac caccggaacg cgatattgcg ccatcagcgc tttagcttgt
     3241 tcaaatgcag gcgcaatatc ttccggttta aagacacgaa ttgctttaca gcctaaccct
     3301 tctgccactt ttacatggtc aacgccatag ccattcactt cgctggagtt gatattttca
     3361 aaggcgagct gcacgcaata gtccatgtca aatgcgcgtt gcgactggcg aatcagacca
     3421 agataagcgt tgttaaccag cacatggata tacggaatgt taaactgcgc gccgacggct
     3481 aactcttcaa tcaggaactg gaagtcgaaa tcgccggaaa tcgccaccac attgcgttgt
     3541 ggatcggcag cacaaacccc taatgccgcc gggattgtcc agccaagagg ccccgcctgg
     3601 ccgcagttga tccagtgtct gtctttaaac acatgcagca tctgcgctgc cgcgatttgc
     3661 gacaatccaa tggtggtgac atagcacaca tcgcgaccaa aggctttgtt catctcttca
     3721 tagacgcgct gcggcttcac tggcacgttg tcaaagtggg ttttacgcag caaagtccgt
     3781 ttacgctgct ggcattcgtc cacccaggtc ttccggcatg gcaaacgccc cgctttttgc
     3841 atctcctgcg cgacatcgat cagcaacgtt agcgccgctt tggcgtcaga aacgatgccc
     3901 agatccgggc acaacacgcg gccaatttgc gtcggttcaa tatcgatatg gatgattttt
     3961 cgaccctgag tatatttctc aacggacccc gtatgacggt tggcgaaacg gttaccgatg
     4021 ccaaaaacca tatcggatgc cagcagagtg gcgttgccgt agcggtgcgc cgtttgcagg
     4081 ccgaccatcc ccgccattaa ggggtgatcg tccagggtac agccccagcc catcagggta
     4141 gggatcaccg gtacgttgat cagttcggca aactgctgca gcagtggcgc ggcgtcggcg
     4201 ttaataaccc cgccgcccgc gacaattacc ggacgctcgg actgaatcag catctccagc
     4261 gccttttcaa tctgtactcg gctggcggct ggcttatata ccggcagcgg ctcatacata
     4321 tccggatcga attcgatttc cgcaacctgg acatcaaacg gtaaatcaac cagcacagga
     4381 cctgggcggc ctgagcgcat cagatgaaaa gcctgctgta atacgcgcgg caccagcgcc
     4441 gcctcacgaa ccgtcactgc catcttgctg actggttttg caatcgcttc aatatcgact
     4501 gcctggaaat cttccttgtg cagacgcgct cgcggcgcct ggccggtaat gcataaaatc
     4561 gggatagagt cggcagaagc ggaatagagc gcggtgatca tgtcggttcc cgccgggccg
     4621 gaagtgccca ggcagacccc aatattacct gccgccgcac gtgtgtagcc ctcagccata
     4681 tgcgaagcgc cttccacatg acgcgccagt atatggcgaa tgcctccatg cttacgcatt
     4741 gcagaataga aggggttgat tgcagcccca ggaacgccga atgctgtggt gataccttct
     4801 ttttccagca catacattgc cgcatccacg gctctcattt ttgccatttt attgctacct
     4861 ctttttattg gaaaaagttt ccaactttta aaaattttaa aaaagtcccg ctccagcgag
     4921 cgggatgcgg ctcaggctac agggggtttt agcccaagcg ccgtactgat gtctttcgcg
     4981 gtatcccgta ccagttcacc ctggctgata aagcgatctt ccgtcagccg ggaagccggt
     5041 cccgatattg agatagcggc gaccacgctg cccgcatcgt catagatagc ggaggcgata
     5101 caattcagcc cgacaacatg ttcttcctgg tcaacggtat agccctgttc acgcgcccgc
     5161 tccagatttt taagcaggat aggtaaatcc accaaagtgg tcggcgtaaa ccgccgcaaa
     5221 ccagtattga caacgatccc caccagctct tcttcggtga gcgggtaaag cagcgctttt
     5281 ccggcgccgg aagcatgtaa cggcagacga ctccctaagg gcgcgcacat tctgaccatc
     5341 gatttgcact ccttttgacc gattaacacc gcttcattac cgttgcgaat cgctacgttg
     5401 accgtctcgc cagaaagcag cataagtcgg tgcataaagg gcccggccac cgagaggaca
     5461 tcgcgattat gaatatacgc agagcccaca ttaaatacgc ctaaaccaat atgccaccag
     5521 ccaagctggc tatcctggta cacaaaatca gccgcttgca gtacctttaa caggcgaaac
     5581 gtcgtagaaa gcggtaaatc caggctgccg gaaatatcgc taactgatga actgccgccg
     5641 cttctttcga gatattgcaa tatcgctatg cccctctcca gcgcctgagc gcctttctgc
     5701 gcagtcggct ctgcctgtcc tggcctgccg cgtcgtctta cttccgtcat atttacgtta
     5761 actccggccc aaaatatgag cataaacaat gaacaatatg ttcatcttat gcaagaaggc
     5821 caatagcgtc acgcaaaaca gagttcatgt gtcgggatac tttcaacatc acagttatcg
     5881 ctgccaccgc gatccaccgt cagaaaatcg gtaaccgtct gccacgcaaa cagcgggtga
     5941 tgccatacat tacggtgata attgacgccc tgccgtccat tgctaataaa cgcccgcagc
     6001 gtggagagat cgggtttatc atcgccgagc gcgacaataa cgacaaaagc ctcgccgttc
     6061 atcggcacaa acgcctgcgt acctaaagga tgacgttcca gttcatgtac cacaataggc
     6121 atcgcggctg gttgcgccct gttaatactg atcagcgtgc gatcctgctc cagaacttca
     6181 accttcgcca ggtcgtgata tcgctcaact aacccgttgt ttatatgaaa aagtcacgtt
     6241 cctgcgtctc aataacatcg ccataggcgc tgaacgtctt ctgatctaac ggtaatacct
     6301 caagtttcat tatttttccc ttgtagctcg attccgttta accgcggttt ggactctgtc
     6361 cggtttcaat accatgcaat ctaaaacctt cgggatttaa catcaacata aaacttggaa
     6421 tatttttcca aaagtagatt tagaccacaa atcaaacatg gctattatgt aaaactactt
     6481 aaaaatcata ggaaaacaat tctggtttta tcaggatcgt aaggaggcgt ctgacgatgt
     6541 ttgacccgga aacactgcgt acctttatca gcgttgccga aacggggagt ttctccaaag
     6601 cggcggagcg cctgtgtaaa accacggcaa ctactagcta ccgcatcaaa ctgctggagg
     6661 aaaataccgg cgtagggctg ttctttcgca caacgcgaag cgtctcgttg acggcggcgg
     6721 gctctcacct tctctctcag gcaaaagact ggcttgcgtg gctggacagc atgcctgacg
     6781 agctacgcca ggttaacgac ggcgtagagc gtcaggtcaa tattgtggtg aataacctgc
     6841 tctatagccc gcaagcggtc gccagtctct tatcgtggct taatgcgcgt taccctttca
     6901 cccagtttca cttttcccgg caaatttata tgggcgtctg ggattcgctc ctgtatgaag
     6961 gtttttcgct ggcgattggc gtaactggca ccgagccgtt ggctaatacc tttatgctcg
     7021 accctttagg ttccgtacaa tggcgttttg tgatgtccgc ggatcatcct ttagctcacg
     7081 tcagcgggcc tctaacagaa gcgcagttgc gccgtttccc ggcaattaat atcgaagaca
     7141 gcgcgcgtac gctgaccaag cgggtagcct ggcgccttcc ggggcagaag gaaattatcg
     7201 tgcctgatat ggaaaccaaa atcgccgctc atctggcagg cgtcggtatc ggttttgttc
     7261 cgcagccgct ttgtcaaacg ctgatcgaca aaaacgaact ggtgagctgt accatcccta
     7321 cgatgcgtcc gccctcaccg ttaagcctcg cctggcataa atttggcgga ggcaaagcgg
     7381 tagaagacat tgtgaaatta tttacccaac gacaacccga aatagccggt tttttatcca
     7441 ttttcaacac ggtacgctgt taaaaatcaa gccactttgc gaattggcgc gtaaaatagc
     7501 gcaaaggatg atttaaggtt acgttttacg ttatgcaaga cagacaaaaa gcacaggact
     7561 atcgcgcact cctccttgcc gatacgcctt taattgatgt acgcgcgccg attgagtttg
     7621 aacagggcgc catgccgggc gctatcaacc tgccattgat gatggacgac gagcgggccg
     7681 ccgtcggcac ctgctacaaa cgtcagggcg cggatgcggc gttagcgctg gggcatcggc
     7741 tggtttgcgg cgacattcgc cagcagcggc ttgaggcctg gaaagccgcg tatcaacgtt
     7801 tccccaacgg gtatctgtgc tgcgcacgcg gcggtcagcg gtcacatatc gtacaacgtt
     7861 ggctgcaaga aacagggatt gactgcccgc ttattgaagg cggctataaa gcgctgcgcc
     7921 agacagcaat tcaggcgacc tggcaactgg cgcaaaaacc gatactttta attggcggct
     7981 gtacgggcag cggcaaaacg caactggtac gacaacagcc caacggcgtg gatctggaag
     8041 gtctcgcgcg tcatcgcggc tcctcttttg gccgcacgct gaaaccccag ctcagccagg
     8101 ccagttttga aaacaaactt gccgttgaat tgctgaaaat taacgcgcgt cagacgctaa
     8161 aaaggtgggt actggaagat gaagggcgaa cgatcggcgc caaccatctg cctgagtgtt
     8221 tacgcgaaag aatggcgcaa gcccccattg cggtagtgga agatccgttt gcgcttcgtc
     8281 tggaacgact gcgtgaagag tatttcatcc gtatgcatca cgacttcacc cacgcctacg
     8341 gcgatggggc cggttggcag gcatatagtg aatatcttca tcatggactg ttcgctattc
     8401 gccgccgtct ggggttgcaa cgctttgccg aactgacgga cacgctggat agggcgctgg
     8461 cagagcaatt atccagcggc agcaccgacg gccatatggc atggctggtt ccgctactta
     8521 acgaatatta cgacccaatg tatcgctatc aactggagaa aaaagccgcg aatatcgttt
     8581 ttcgcggcac atggcaagac gttgccaact ggctaaaagc gcaatagctt atttttattg
     8641 ccggctgacg ctacattgag ccggcttagt gtctgtcgcg cttgtcggca cgttttgcca
     8701 gccagtcgcc cagcatctga acgacctgaa ccagcacaat cagcgccact acggtaacaa
     8761 ccatcacttc ggtttcgtaa cggtagtagc catagcgaat cgccaggtcg cctaccccgc
     8821 cgccgccgac aatcccggcc atcgccgagt agccgattaa gcttaccagc gtaatcgtca
     8881 ggccgcgcag cagccctgcg ctggcttccg gcaacagtac ggtacagata atacgcatcg
     8941 gactagcgcc gaatgccagc gccgcctcaa taatcccttt atcgacttca cggagcgcgc
     9001 tatctaccag gcgtgcataa aacgcgattg cggccaccga cagcgggacg gaggctgcaa
     9061 tcgggcctat cgtattgccc agcaaaagct gcgttagcgg cagtaacagc accagtaaaa
     9121 taacaaatgg caccgagcgg ataatattca ccagaaccga ggcgacaaga taaataaaac
     9181 ggttctgcca gaacagatga cgatcggtga caaaaatcag aaaaccgagc ggtagaccgc
     9241 caagaatcgc cagcaccgtt gaaatactca acatctggaa agtttcattg aacgccagcg
     9301 ttaaatccgg caataaatca tccacggatc acctccacct gtgcagtacg ttgacggata
     9361 tgctccacgg cggccgccac cgccgttgga ttatgcggcg cggttaattg caccaccaga
     9421 atgcccaacg cgcgttcgcc gatatactca atcttgccat gcaggatatt gaccgcgacg
     9481 ccaaacttga tcgccacctc cgacagtacc ggctgctccg ccgaatcgcc gataaacaaa
     9541 attttcagca actgcccggg caggtgttcc cgtaagcgtt ccggcagggt caaattaagg
     9601 gtatgagaca ccagttgctg tgtgaaagcg tgttgcgggt gggcaaacac atcaaacacc
     9661 tcgcccgatt ccacaacctt accgcccgac atcaccgcca cgcgatcgca aatagatttg
     9721 atcacgttca tttcatgggt gatcagcaca atagtaatcc cgagctgcgc gttgatctgt
     9781 ctgagcaggg ccagaatcgt ggcggaagtt tccagatcca gagcggaagt cggttcgtca
     9841 cacagcaaaa catccggatg gttagcgatg gcgcgggcta tccccacccg ctgtttttgc
     9901 ccgccgctga gctgtaccgg aaaacagttc gctttatcgg caaggcccac cagcgttaaa
     9961 atttccgcca cccgcggcgc gattttgctg cgttcccagc cagccgcttt caggctaaac
    10021 gccacgtttt tcgccactgt ccgggtatgc attaagttaa aatgctggaa aatcatacca
    10081 atacgctgcc gcgcctggcg taacgctttt ccgtccagcg cagaaatttc cacgccgttg
    10141 acgttgacgc gcccctgact gggacgcgtt aaggcgttca gggtacgcag cagagtgctt
    10201 tttcctgcgc cgctggtacc gacaatgcca aaaatctcgc ccgcggcgat atgcaggctc
    10261 acatcatcca ccgcgcgcgt gggggtaccg cgaccggcgg taaaatcgac gcagactttt
    10321 tctatttcaa tcatattcac ctcagaaatt ggggatggcc accgctgcga tcagggtgtc
    10381 gcggtcatcc attccggttt ctggaaggcg ctataaatat tctttggatc gtcgatgacc
    10441 gcgcgataag ccggcgattt caccgcctcg acaatatctt tggcaaacgg cttatcggca
    10501 tcttcactgc gtaccgcaat gatatttttc agattctcat ccaggtgttc ctgcttaatc
    10561 gcgctggaga gatcgagtcc tgccgccacc gcaaagttcc cgttaaccag cgcgccggtc
    10621 acgccgtcca gcgtgcgcgg tagctgtgcg gcttccagcg gtttgaaaac cagtcctttt
    10681 ggattgctgg cgatatctcg ttcagaggct ttggtcggat cgatattgtg cttaatcgtg
    10741 ataagcccca acgattgcag gaagcgaagg ccgcgcgcca ggttggtcgg atcgttggag
    10801 agggtaataa tgtccccttt tttaagcgca tccaggctgt tgattttacg tgaatagaag
    10861 cccatcccgg cggtcggtac cacaataagt ttgctgagct tcagcccttt gtcagcggtg
    10921 aatttgtcaa aatagagggt atgttgaaag aggttggcgt cgatgctgcc gttagctaac
    10981 gccatattgg gctggacata gtcgctaaac tcgcgcacca cgaccttata ccctttttct
    11041 tttaatgtcg gcgcaatcgc ctgcttcacc atgtcgccat acggccctgg cgcgacgcca
    11101 aatacgatcg tttgcgggga accatcggca tgggcaaact gtaatccgca ggccagtaat
    11161 agcgtgctgg ccgcaatgcg taaactctga cgcaatccca taatttctcc attttaaata
    11221 gtgtgatgct gtgccggatg ccgttcatgc ggcatcgtct gttttggccc aaacgaaagg
    11281 ctatttctta acatgacaca gatcacagcc tgctgtcctt gaaattattt catgatgttt
    11341 cctggtgtgt cgttaaatgt acgaggcagg cgctcaggcg tgtgtcaggc gggaatggcg
    11401 taaagggaaa tgccggataa gacgtcttaa cgccaacatc cggcacagga aaacgcttta
    11461 gaaatcgtaa cgcagacgca ccaggttcat atcgcccaga ttgtcagtgc tggaggtgaa
    11521 aacatgttca taatcaacgc ggaaaccata atccagttgg aaggtgatcc ccacgccgtt
    11581 atcggtgcgc agatagtcgc ggccattcac atattcaatg cggtcgccca taaagtacgg
    11641 ttgaatagct ttcacggcat actgaccaat cgggaaagcg taaccgacaa aatattccag
    11701 accccacgca tcgccggcaa agtaatcatt cacagacact tttttggtcg tcataaagtt
    11761 ctgataccaa ccgccgcctg cggcaatagt ccagttttcc ggcgtccagc ttaacgcggt
    11821 accgacaata ttttgatcgt aagttttatt gccgttgccg cgcatctccg cacgggtata
    11881 gttccatgcc gtcccccagg tcagatcgtc ggtgagatgg taatccgcgc ctaaagaacc
    11941 gccgccttta cgtttgtaat tcaggccgtt attggcatta taatcgtcgc tgaacagata
    12001 agacgcgtag agatcgacat tgccaatgct tttcttatac ttcaatgact tacgcgtacg
    12061 gtaagaacca tcgtagtcgc cgttaatccc gttgcccggc gcctgaccta tcatgtcgta
    12121 atcccagata tcggttttta cgcccaccac atcgtaataa atgctgttct gttgaccgaa
    12181 ggtcagcgtt ccccacgtcg cgctcttgaa gccagtatac agcatacggc gagtggtatc
    12241 agtcgtgccc ttcgcataat ggttatccca gtcaaatacc gcagggatat tgacgcccag
    12301 ctcgtaatag ctaatccaac tgatatcatc aaacagataa taatccgcgg cgaagcggaa
    12361 acgcgtcccg ccatcaaaac cattacgttt ata
//
LOCUS       DAJVBX010000140        12361 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.140, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000140 DAJVBX010000000
VERSION     DAJVBX010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 12361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12361
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.140"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(326..580)
                     /locus_tag="OPV72_003203"
     CDS             complement(326..580)
                     /locus_tag="OPV72_003203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001675765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HCR9915424.1"
                     /translation="MDCRSGCGACCIAPSISSPIPGMPNGKPMNTRCVQLSEDNLCLI
                     FGSPLRPKVCSGLQPTGDMCLTTREEAIIYLLELEQKTLP"
     gene            905..1477
                     /gene="yeiP"
                     /locus_tag="OPV72_003204"
     CDS             905..1477
                     /gene="yeiP"
                     /locus_tag="OPV72_003204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007750416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P-like protein YeiP"
                     /protein_id="HCR9915425.1"
                     /translation="MPRANEIKKGMVLNYNGKLLIVKDIDIQSPTARGAATLYKMRFS
                     DVRTGLKVEERFKGDDIVDTVTLSRRGVDFSYVDGNEYVFMDKEDYTPYTFTKDQIEE
                     ELLFMPEGGMPDMQVLTWDGQLLALELPQTVDLEIVETAPGIKGASASARNKPATLST
                     GLVIQVPEYLSAGEKIRIHIEERRYMGRAD"
     gene            1690..2676
                     /locus_tag="OPV72_003205"
     CDS             1690..2676
                     /locus_tag="OPV72_003205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HCR9915426.1"
                     /translation="MTKTNLITGFLGSGKTTSILHLLAHKDPAEKWAVLVNEFGEVGI
                     DGALLADSGALLKEIPGGCMCCVNGLPMQVGLNTLLRQGKPDRLLIEPTGLGHPKQIL
                     DLLTAPVYEPWIDLRATLCILDPRLLLDQQSVANENFRDQLASADIIIANKTDRATAQ
                     SDAALQQWWRQYGGDRQLIHAEHGQIDGKLLDLPRQNLAELPASAAHSHTHASKKGLA
                     ALNLPAQQRWRRSLNSGQGHQACGWIFDADTVFDTIGLLEWARLAPVGRVKGVMRIQE
                     GLVRINRQGDDLHIETQSVAPPDSRVELISNTETDWNTLQTALLKLRLATHA"
     gene            2706..3425
                     /locus_tag="OPV72_003206"
     CDS             2706..3425
                     /locus_tag="OPV72_003206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HCR9915427.1"
                     /translation="MTMKTRYSLIILLNAAGLALFLSWYLPVNHGFWFTIDSGIFHFF
                     NQKLVESHAFLWWVAITNNRAFDGCSLLAMGGLMLSFWLKEDASGRRRIVIIGLVMLL
                     TAVVLNQLGQALIPVKRASPTLSFEHIYRVSELLHIPTKDASKDSFPGDHGMMLLIFS
                     AFMLRYFGKTAGIIALIIFVVFAFPRVMIGAHWFTDIVVGSLTVILIGLPWWLMTPLS
                     DRAIALFEDYLPGGNKQILNK"
     gene            3839..4411
                     /gene="mepS"
                     /locus_tag="OPV72_003207"
     CDS             3839..4411
                     /gene="mepS"
                     /locus_tag="OPV72_003207"
                     /EC_number="3.4.17.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional murein DD-endopeptidase/murein
                     LD-carboxypeptidase"
                     /protein_id="HCR9915428.1"
                     /translation="MVKSQPILRYILRGIPAIAVAVLLSACSTTTNTAKNMHSETHAV
                     GNSDSSSLQASQDEFENMVRNLDVKSRIMDQYADWKGVRYRLGGSTKKGVDCSSFVQR
                     TFREQFGLELPRSTYEQQEMGKAVSRNNLRTGDLVLFRAGSTGRHVGIYIGNNQFVHA
                     STSSGVIISSMNEPYWKKRYNEARRVLSRS"
     gene            4737..6293
                     /locus_tag="OPV72_003208"
     CDS             4737..6293
                     /locus_tag="OPV72_003208"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic di-GMP phosphodiesterase"
                     /protein_id="HCR9915429.1"
                     /translation="MLTRDSSSGRKILLTCIITGIAAALLIGSLQFFLSWHKRDVKYN
                     TLLSDVQHYLASYFADLKATTDILQPLTINTCQQVGAELTSRAAFSLNVRAFLLIKDK
                     KVFCSSATGAMNMPLQQLVPDIDIRKDVAMAILPGTPMMPNKPTMVIWYRNPLLNNSG
                     VFTSLNINLTPYLLYTTRQDDFNGIALIVGNTALSTFSSRLLTVAELPGTPSRQATIN
                     GLPLKIQLYADSWTYNDLWYALMLGCISGIVAGFICYFIYALRTRPGKEILTAIKHEQ
                     FYVVYQPVVDTRTLSVTGLEVLLRWRHPTAGEIPPDAFIHYAEAQQLIVPLTQHLFEL
                     IARDAPTLQKVMPVGAKFGINIAPEHLHSDSFKEDMHRLRDALPAHHFHIVLEITERN
                     MLQQYEAAKLFEWLHSAGFEIAIDDFGTGHSALIYLERFTLDYLKIDRGFIQAIGTET
                     VTSPVLDTVLTLSRRLNMLTVAEGVETPEQARWLRDHGVNYLQGYWISRPLPLKDFVL
                     WMSAPSVPEW"
     gene            6400..8205
                     /locus_tag="OPV72_003209"
     CDS             6400..8205
                     /locus_tag="OPV72_003209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCR9915430.1"
                     /translation="MIARVMLLLVALVSAGAQAQEIKESYAFAVLGEPKYAFNFDHFD
                     YVNPAAPKGGQMTLSAIGTFDNFNRYSLRGNPGVRTEALYDTLFTTSDDEPGSYYPLI
                     ADHARYAADYSWVEISINPRARFHDGTPITARDVAFTFHKFMTEGVPQFRLVYKGTTV
                     KAIAPLTVRIELAKPGKEDMLSLFSLPIMPEKFWKNHKLSDPLSTPPLASGPYRITQW
                     KMGQYIVYSRVKNYWAANLPVNRGRFNLDTVRYDYYLDDNVAFEAFKAGAFDLRLEND
                     AKNWATRYIGKNFDNHYIIKEEQKNESAQDTRWLAFNIQRPVFKDRRVREAVTLAFDF
                     EWMNKALFYNAWSRTNSYFQNTEYAARNYPDADELVLLAPMKKDLPPEVFTQIYQPPV
                     SNGDGYDRENLLKADALLTQAGWVINGQQRVNSVTGKPLTFELLLPASSNSQWVLPFQ
                     HNLQRLGITMTIRQVDNSQLTNRMRSRDYDMMPRLWRAMPWPSSDLQISWASEYIDSS
                     YNAPGVQSPVVDKLIAQIIAAQGDKAKLVPLGRALDRVLTWNYYMLPMWYMAQDRLAW
                     WDKFSHPAIRPVYTIGLDTWWYDVNKAAKLPAARR"
     gene            8215..9309
                     /locus_tag="OPV72_003210"
     CDS             8215..9309
                     /locus_tag="OPV72_003210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="microcin C ABC transporter permease YejB"
                     /protein_id="HCR9915431.1"
                     /translation="MGAYLIRRLLLVIPTLWAIITINFFIVQIAPGGPVDQAIAAIEF
                     GQGGALPGASGEGVRASHAQTGVGNISDSHYRGGRGLDPEVIAEITHRYGFDKPLHER
                     YFKMLRDYLSFDFGDSLFRSASVLTLIKDSLPVSITLGLWSTLIIYLVSIPLGIRKAV
                     HNGSRFDVWSSAFIIIGYAIPAFLFAILLIVFFAGGSYYDIFPLRGLVSANFDTLPWY
                     QKITDYLWHITLPVLATVIGGFAALTMLTKNSFLDEVRKQYVVTARAKGVSEKNILWK
                     HVFRNAMLLVIAGFPATFISMFFTGSLLIEVMFSLNGLGLLGYEATVSRDYPVMFGTL
                     YIFTLIGLLLNILSDISYTLVDPRIDFEGR"
     gene            9309..10334
                     /locus_tag="OPV72_003211"
     CDS             9309..10334
                     /locus_tag="OPV72_003211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR9915432.1"
                     /translation="MPRLSPVNQARWARFRHNRRGYWSLWIFLVVFSLSLCAELIAND
                     KPLLVRYEGQWYFPLVKNYSERDFGGPLATTADYQDPWLQRQLENRGWVLWAPVRFGA
                     NTINFATTQPFPSPPSAKNWLGTDANGGDVFARILYGTRISILFGLMLTICSSVMGVL
                     AGALQGYYGGKVDLWGQRLIEVWSGMPTLFLIILLSSVVQPNFWWLLAITVLFGWMSL
                     VGVVRAEFLRTRNFDYIRAAQALGVSDRDIILRHMLPNAMVATLTFLPFILCSSITTL
                     TSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLGIAAFLSVAILLSLLIFIGEAVRDA
                     FDPAKAV"
     gene            10336..11925
                     /gene="yejF"
                     /locus_tag="OPV72_003212"
     CDS             10336..11925
                     /gene="yejF"
                     /locus_tag="OPV72_003212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="microcin C ABC transporter ATP-binding protein
                     YejF"
                     /protein_id="HCR9915433.1"
                     /translation="MTSPLLAIENLSVGFRQQQHVRPVVNAISLQVNAGETLALVGES
                     GSGKSVTALSILRLLPTPPAVYLSGDIRFHGESLLHASEQTLRGVRGNKIAMIFQEPM
                     VSLNPLHTLEKQLYEVLSLHRGMRREAARAEMIGCLDRVGIRQASQRLRDYPHQLSGG
                     ERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILSLLRELQRELNMGLLFITHNLS
                     IVKKLADSVAVMQHGKCVENQRADTLLSAPTHPYTQKLLNSEPTGDPVPLPAGQAPLL
                     EVDKLRVAFPIRKGILKRVVDHNVVVNNISFTLHPGETLGLVGESGSGKSTTGLALLR
                     LIRSEGRIVFDGQSLDTLNRRQLLPVRHRIQVVFQDPNSSLNPRLNVLQIIEEGLRVH
                     QPTLSGAQREQQVKAVMMEVGLDPETRHRYPAEFSGGQRQRIAVARALILKPSLIILD
                     EPTSSLDKTVQAQILALLKSLQQKHRLAYIFISHDLHVVRALCHQVIVLRQGEVVEQG
                     QCERVFTAPQQAYTRQLLALS"
     gene            complement(11929..12273)
                     /locus_tag="OPV72_003213"
     CDS             complement(11929..12273)
                     /locus_tag="OPV72_003213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915434.1"
                     /translation="MNTLQLSIVHRLPQNYRWSAGFAGSKVEPIPQNGQSTENSLVAL
                     KLLSPAGDSAWSVMHKLSQALSDIEVPCSVLECEGEPCLFVNRQDEFAATCRLKNFGV
                     AIAEPFSNNNPF"
BASE COUNT         2903 a         3295 c         3073 g         3090 t
ORIGIN      
        1 aaactaatga tatcgatcgt tataaataat taaaatcgat caaaattcct ctttttaata
       61 gataaaaact atcatataaa taaaattgat cgcttttgtt ttatgtgacg gtttgttcgg
      121 tacacgttca ggcaccaacg gggttgagcg gcgacatcta ccgtttcaga agacacgaaa
      181 taagggaagc atgtattacg ctatttaatg gtaaaaggag gtaatttgat gcgcagcttt
      241 tgcagactat ttcgggatat aacgtaagcc cctgcacgtt tatcaaaaac agctgactta
      301 gagcctatcc cattaggcta ttagctcatg gtaaggtttt ctgttcgagt tccagcaaat
      361 aaataatggc ctcttcccgg gtcgttaaac acatgtcccc tgtcggttgc aaaccagagc
      421 acacttttgg gcgtaaaggc gagccaaaga taagacacaa gttatcttcc gaaagctgca
      481 cgcatctggt attcatcggc ttgccattcg gcattccggg tatcggcgac gaaattgaag
      541 gcgcaataca gcaagcgcca caaccgctac gacagtccat gctcagcccc tctatttata
      601 accaaatgaa agataacaga atttgtccaa agaaaaatcc agatttaaaa tgtggacgtc
      661 atcatgatca ggcctgtcct cagacattcc gaagacaagg ctggaaacag aagggacaac
      721 acagcacact tcccccctcc aggcgacatg ccatcgcgta ttctcgttga acgcggagcg
      781 gaaagcgggc gaacagtatc accttttttg caccagcaaa agtgacaatt ccacttgcct
      841 ggacggcccg gcgcgagtag ttttacgcga tattttagat aatctctaca acaggatctc
      901 ctcgatgcca agagcgaacg aaatcaaaaa aggtatggta ctgaactaca acggcaaatt
      961 gctgattgtg aaagatatcg acattcagtc gcctaccgcc cgtggcgccg ccacactgta
     1021 taaaatgcgc ttttccgatg tccgcaccgg tctgaaagtg gaagaacgtt tcaaaggcga
     1081 cgatatcgtt gataccgtca ccctgagccg tcgcggcgtt gacttttctt atgtcgatgg
     1141 caacgaatat gtgttcatgg ataaagaaga ctatacgccg tataccttca ccaaagatca
     1201 gattgaagaa gagttgctgt ttatgcctga aggcggaatg ccggatatgc aggttctgac
     1261 ctgggacggc caactgctgg cgctagagct tccgcagacc gtggatctgg aaatcgtcga
     1321 aaccgcgccg ggtattaaag gagcgtccgc cagcgcacgt aacaaacccg cgacattaag
     1381 caccggtctg gtgattcagg ttcccgaata cctgagcgca ggtgagaaaa tccgcattca
     1441 tatcgaagag cgccgttata tggggcgcgc ggattaagtt tcacattttt cggctgcgcc
     1501 ccagggcgca gtctgcccct tttatttatt gactgttctg caccaggcaa gagaaacgtt
     1561 aaaaatttaa cattttctgc tcttaagatg gcagaagcac gacttcgtca actcagcact
     1621 tctctttttc acgtttattc gccaggatta ttaaaagttg ttatgttgta tcaatattct
     1681 ggagctgacg tgaccaaaac caatcttatt actggatttc tcggtagcgg aaaaaccacc
     1741 tctatccttc atttattagc tcataaagat ccggctgaaa agtgggccgt cctggttaat
     1801 gaatttggtg aagtgggtat tgacggcgcg ctgcttgccg acagcggcgc actgctaaaa
     1861 gagattcccg gcggctgcat gtgctgcgtc aacggattgc ctatgcaggt ggggctcaac
     1921 acgctgctgc gccagggcaa acctgaccgg ttgctgattg aaccaaccgg actggggcac
     1981 ccaaaacaga ttctggattt attaactgcg ccggtttatg agccgtggat tgatttacgc
     2041 gccacgctct gcatcctgga ccctcgcctg ctactggacc aacagagcgt cgccaatgaa
     2101 aatttccgcg atcagctcgc ctcagccgat attatcatcg ccaataaaac cgaccgcgcc
     2161 acggcgcaga gcgatgccgc cctgcaacag tggtggcgac agtacggcgg cgatcgtcaa
     2221 ctgattcatg ccgaacatgg acagatagac ggtaagcttc tggatttacc gcgacaaaat
     2281 ctggcggaac tgccggccag cgccgcgcat tctcacactc atgccagtaa aaaaggactc
     2341 gccgcgctaa atctgcccgc acagcagcgc tggcgacgca gcctcaatag cggacagggt
     2401 catcaggcct gcggctggat tttcgatgcc gataccgtgt ttgacaccat tggcctactc
     2461 gaatgggctc gtctggcgcc ggtgggccgg gtgaaaggcg ttatgcgcat acaagagggg
     2521 ctggtacgca tcaatcgcca gggcgatgac ctgcacatcg aaacacagag tgtcgcgccg
     2581 ccggatagcc gggttgaact tatctcaaac acagaaaccg actggaatac gttacagacg
     2641 gccttgttga agcttcgttt agcgacgcac gcgtaaggtt gccaccgttt aaaaactatg
     2701 gcgaaatgac gatgaaaacc cgctattcct tgataattct gcttaatgcc gccggtctgg
     2761 cgctgttttt gtcatggtat cttcccgtca atcacggttt ctggttcacc attgattccg
     2821 gcatattcca cttctttaac cagaaactgg tggaaagcca cgcgttcctc tggtgggtcg
     2881 ctattaccaa taatcgggcg tttgacggct gttcgctgct ggcgatgggc ggactgatgc
     2941 tcagtttctg gctaaaagaa gacgcgtcgg gccggcggcg cattgtgata atcggattgg
     3001 tcatgctgct aacagcggtg gtgcttaacc aactcggtca ggcgctgatc cccgtcaagc
     3061 gcgccagtcc aacgctctct tttgagcata tttatcgcgt cagcgagttg ctgcacatcc
     3121 cgacaaaaga cgcgtcaaaa gacagtttcc caggcgatca cggtatgatg ctgctgatat
     3181 tttccgcctt tatgctgcgt tatttcggca aaacggcggg gattatcgcc cttattatat
     3241 ttgtggtttt cgcgtttccg cgcgttatga ttggcgctca ctggttcacc gatattgtgg
     3301 ttgggtcgct cacggttatt ttgattggcc tcccctggtg gctgatgacc ccgctcagcg
     3361 accgggcgat agcgcttttt gaggattatc tcccgggcgg aaataaacaa attttaaaca
     3421 aataacccat acaattaaca ttgccttcag cgatagtttt acatcgttga aggtaattta
     3481 tgatgatatt cccccagccc atcatttttc ggtaatatta ttcctctgca aaatgaacag
     3541 gttgcacgat ttttaaacga tttgcgctta atttgacccg tgctgatagc tcacttttcg
     3601 tatcataaat tcttataaaa aatcacgcga aatcgctcgc aatgacagca acaatcgggt
     3661 aatctcaaac tcgttttgcc tcgccagata attattctca ttgcgaataa atttgtgcgt
     3721 tccgccacag atttgtgcac aaagaattgt ctcaagctgt gcaggtaatt agtctcatca
     3781 cgtttggcat ttttataacg atatttatcg ttaaggactt caagggaaaa caaacaacat
     3841 ggtcaaatct caaccgattt tgagatatat tttgcgcggg attcctgcga ttgcagttgc
     3901 ggttctgctt tctgcttgta gcacaaccac caataccgca aagaatatgc attctgagac
     3961 gcatgctgtg ggcaatagcg atagctcttc actgcaagcc tctcaggatg aatttgaaaa
     4021 tatggtgcgt aacctcgacg ttaagtcgcg gattatggat cagtatgctg actggaaagg
     4081 tgtgcgttac cgcctgggcg gcagcactaa gaaaggcgtc gactgttcca gctttgtaca
     4141 gcgcaccttc cgcgaacagt ttggtttaga gcttccgcgt tcaacctatg aacagcagga
     4201 aatgggcaaa gcggtttcac gcaataacct gcgtacgggc gatctggttc tgttccgcgc
     4261 cggttccact ggccgtcatg tcggtattta tatcggcaat aaccaatttg tccatgcgtc
     4321 taccagtagc ggcgtcatta tctccagtat gaacgaaccg tactggaaaa aacgctacaa
     4381 tgaagcgcgt cgagttctga gccgcagtta atcttcatca ggcagcacct cccttggctt
     4441 acctgatgag acgacataaa aagcactgct tcagcagtgc ttttgcttat tatcccttct
     4501 gaacccgttt taccgaatag cgacgtgtcg cctcttatcc agcctacaac acacgaacat
     4561 aggcctgata aacatagcgc catcagacat tcaggtcgtt tccgccaacg actactgcga
     4621 caatacgctt tcctgcgcat cacagaaaag catgactatc cggggtaatc caggctatag
     4681 tcttataaat caaccagttt aaccggcatc tgccttttca ggtcacacca ggaattatgc
     4741 ttacacgcga ctcctcttcc ggtcggaaaa tcctgcttac ctgtatcatt acggggatag
     4801 cggcagcatt acttattggt agcctgcaat ttttcctgtc gtggcataaa cgggatgtta
     4861 aatacaatac gctcctttct gatgtacaac attacctagc cagctatttc gccgacctga
     4921 aagccaccac cgatattctt cagccgttga cgatcaacac ctgtcagcag gttggcgcag
     4981 aactcacctc aagagccgct tttagcctta atgtccgcgc cttcttattg attaaagata
     5041 aaaaagtgtt ctgctcttcc gccactggcg ccatgaatat gccgcttcag caactggtac
     5101 cggatataga tatccgcaaa gacgttgcta tggcgattct gcccggcacg ccaatgatgc
     5161 ccaacaaacc gacaatggtg atttggtatc gaaacccatt attaaataac agcggcgtat
     5221 tcacatcgct gaatattaac ctgacgccct acttactcta taccacgcgc caggacgatt
     5281 ttaacggcat cgcgctgatt gtcggcaata ccgcgctgtc gaccttttct tcgcgtctgc
     5341 tgaccgtcgc ggagctgccg ggcacgcctt cacgacaggc aactatcaac ggcctgccgc
     5401 ttaaaataca gctttatgcc gatagctgga cctacaatga cttgtggtat gcgttgatgc
     5461 tgggctgcat tagcggcatc gtagcggggt ttatctgtta ctttatctat gccctccgga
     5521 cgcgaccggg caaagagatt ttaacggcga tcaaacacga gcagttttat gtggtttatc
     5581 agcccgtcgt cgatactcgt acgctaagcg tcaccgggct tgaagtctta ctgcgctggc
     5641 gtcaccctac ggcaggcgag attccgccgg atgcctttat ccactatgcc gaagcgcagc
     5701 aacttatcgt accgttaacg cagcatctgt tcgagctgat cgcccgcgac gcacccacgc
     5761 tacagaaggt gatgcccgtc ggtgccaaat ttggcattaa catcgcgccg gaacatctgc
     5821 acagcgacag ttttaaagag gatatgcacc ggctcaggga cgccctgccc gcgcaccatt
     5881 ttcatatcgt gctggaaatc actgaacgca atatgcttca gcagtatgaa gcggccaaac
     5941 tgttcgaatg gctgcattcc gccgggtttg aaatcgctat agatgatttc ggtacaggcc
     6001 atagcgccct gatttatctg gagcgattta ctttagatta tctgaaaatt gatcgcggct
     6061 ttatccaggc gatcggcacg gaaaccgtca cgtctccggt tctggatacc gtgctgacgc
     6121 tctccagacg cctgaatatg ctgacggtgg ccgagggcgt tgaaacgccg gagcaggccc
     6181 gttggctacg cgatcacggt gttaattact tgcaggggta ctggattagc cgtcctttac
     6241 ccctaaaaga tttcgtgctg tggatgtcgg cgccttccgt gcctgaatgg tagtcccctt
     6301 acggttttaa cggattcaca tcagacgcaa cgtcacttat tattcagcga aacgcctgcc
     6361 ggtttgcagc gggcaatacg ataaggaaac cgccttcaga tgattgcgcg cgtaatgctt
     6421 ctgcttgtcg cactggttag cgctggcgcc caggcccagg aaatcaaaga aagctacgct
     6481 ttcgccgtac tcggcgaacc taagtatgct tttaactttg atcactttga ttatgtgaat
     6541 cctgctgcgc cgaaaggcgg tcagatgacg ctttccgcca ttggtacgtt cgataatttc
     6601 aatcgctatt cgctgcgcgg caatcccggc gtacgtaccg aagcccttta cgatacgctt
     6661 tttaccacct cggatgatga acccggaagc tattacccgc tgattgccga ccatgcccgc
     6721 tatgccgccg actattcctg ggtggaaatc tcgattaacc cccgcgctcg ttttcacgat
     6781 ggcacgccca ttaccgcccg cgatgtagcc tttacctttc ataagtttat gaccgaaggc
     6841 gtaccgcagt tccgtctggt ctataaaggt actaccgtga aggcgattgc gcctttaacc
     6901 gtgcgaattg agctggcgaa gcctggtaaa gaagacatgc ttagtctgtt ttcactaccg
     6961 atcatgcccg aaaaattctg gaaaaatcac aaactcagcg atccactttc aacgccgccc
     7021 ttagccagcg ggccataccg gattactcag tggaaaatgg gccagtacat tgtctattca
     7081 cgcgtcaaaa actactgggc ggctaatctg ccggtcaatc gtggacgttt taacctcgac
     7141 actgtccgct acgattacta ccttgatgac aatgtcgctt tcgaggcgtt taaagcgggc
     7201 gcatttgatc tacggctgga aaacgacgct aaaaactggg caacgcgcta tatcggtaaa
     7261 aatttcgata atcattacat cattaaagaa gagcagaaaa acgagtcggc gcaggacaca
     7321 cgctggctgg cctttaatat tcagcgcccg gtatttaaag accggcgggt acgtgaagcc
     7381 gtcaccctgg ccttcgattt tgagtggatg aataaagcgc tgttctataa tgcctggagc
     7441 cgaaccaaca gttacttcca gaataccgag tacgccgcca gaaattatcc tgacgccgac
     7501 gaactggtat tactcgcgcc gatgaaaaaa gatcttcctc ctgaagtctt cactcagatc
     7561 tatcagccgc cggtctctaa cggcgacggc tacgatcgcg aaaatcttct taaagctgac
     7621 gccttgttga cgcaggccgg atgggtgatc aacggacagc aacgggtcaa tagcgtcacc
     7681 ggtaagcctc tgacgtttga acttctcctt cctgccagca gtaatagcca gtgggttctg
     7741 cccttccagc ataatcttca gcgtctgggc attacgatga ctatccgtca ggttgataat
     7801 tctcaactca ccaaccggat gcgtagccgc gactatgaca tgatgccgag gctatggcgg
     7861 gcgatgccct ggcccagctc cgatctacaa atctcatggg cgtcggaata cattgactcc
     7921 agttataacg ctcccggcgt acaaagcccg gtggtggata agctgatcgc gcaaattatc
     7981 gcagcgcagg gtgataaagc gaaactggtg ccgctgggac gggcgctgga tcgcgtgctg
     8041 acctggaact attacatgct gccgatgtgg tatatggcgc aagacaggct cgcctggtgg
     8101 gataaattct cccatccggc gattcgcccg gtatatacca tcgggttaga tacctggtgg
     8161 tatgatgtca acaaagccgc caagctaccg gcagccagga ggtagtaaga atcaatgggt
     8221 gcctatctta tccgccgtct gttactggtg atccccacgc tatgggccat tattaccatt
     8281 aactttttta tcgtgcagat cgctcccggc ggccctgtcg atcaggctat tgccgcgatt
     8341 gaatttggtc agggcggcgc gttgcccggc gccagcggcg aaggcgttcg cgccagtcat
     8401 gcgcaaaccg gcgtcggcaa tatcagcgac agccattatc gcggcggccg gggactcgat
     8461 ccggaggtga tcgcggagat cacccatcgc tacggcttcg acaaaccgct gcatgagcgt
     8521 tatttcaaga tgctacggga ctatctctct tttgacttcg gcgacagtct gtttcgcagc
     8581 gcatccgtac taacgctgat caaagatagc cttcccgtct ccattaccct gggattatgg
     8641 agcacgctga ttatttatct ggtgtctatc ccgctgggga ttcgcaaagc cgtccataac
     8701 ggcagtcgct ttgatgtgtg gagcagcgcg tttatcatta ttggttatgc gatccccgcc
     8761 tttctgttcg ctattttatt aatcgtcttt tttgccggcg gcagctacta cgatatcttt
     8821 ccgctacgtg gcctggtctc cgccaacttt gacacgttac cgtggtacca gaaaatcacc
     8881 gattatttgt ggcatattac gctgccggtg ttggcgaccg tcatcggcgg ttttgccgcc
     8941 ctgacgatgc tgacgaaaaa ttcgtttctc gacgaggtgc gtaaacagta tgtcgttacc
     9001 gctcgcgcta aaggcgtgag tgaaaaaaac attctctgga aacatgtttt tcgtaacgcc
     9061 atgctgctgg tgatcgccgg gtttcccgcc acttttatca gtatgttttt caccggctcg
     9121 ttgctaattg aagtcatgtt ctcgctcaac ggcctggggc tgctgggtta tgaagcaacc
     9181 gtttcgcgcg actatccggt gatgttcggc acgctttata tctttaccct gattggctta
     9241 ttactgaata tcctgagcga tatcagctat acgctggtcg atccacgcat tgattttgag
     9301 ggacgataat gccgcgatta agcccggtca atcaggcccg ctgggcgcgt ttccgccata
     9361 atcgccgggg ctactggtca ctatggattt tcctggtagt gttcagcctg agcttatgcg
     9421 cggaactgat tgctaacgat aagccattgc tggtgcgcta tgaaggccag tggtattttc
     9481 cgctggtaaa aaattacagc gagcgcgatt tcggcggccc gctggcgaca acggcagact
     9541 atcaggaccc ctggctacaa cggcagcttg agaatcgggg ctgggtgttg tgggcccccg
     9601 tacgctttgg cgccaatacc attaattttg ccaccacgca gcctttcccc tccccgcctt
     9661 cggcgaaaaa ctggctgggc accgatgcga atggcggcga cgttttcgcc cgcatcctgt
     9721 acggcacccg catttctatt ttatttggcc tgatgttaac gatttgctcc agcgtcatgg
     9781 gtgtactggc gggcgcgcta cagggctatt atggcggcaa agtcgattta tgggggcaac
     9841 gtctcatcga agtctggtcg gggatgccga ccctgtttct gattatttta ctttccagcg
     9901 tagtgcagcc taacttctgg tggctgctgg ccataaccgt gctgtttggc tggatgagtc
     9961 tggtgggcgt ggtgcgcgcc gagtttttac ggacccgcaa ttttgactat atccgcgccg
    10021 cgcaggcgct tggcgtcagc gatcgtgaca ttatcctgcg ccatatgttg cctaatgcga
    10081 tggtcgctac cctgacattt ttaccgttca ttttatgtag ttccatcacc accctgacgt
    10141 cgctggattt tctgggattc ggtctgccgc ttggctcccc ttctctcggc gaacttcttt
    10201 tacaggggaa aaacaactta caggctccct ggctggggat cgccgccttt ctgtctgtcg
    10261 ccattctgct atcgctgctg atttttatcg gcgaagcggt acgcgacgcc tttgatcctg
    10321 ctaaggcggt ataagatgac atctccattg cttgcgattg aaaatttatc ggtaggtttc
    10381 cgtcagcaac agcacgtgcg ccctgtcgtt aacgccattt cgttacaggt gaacgccggg
    10441 gaaacgctgg cgctggtcgg cgagtcaggg tcaggaaaaa gcgtgacggc gctttccatt
    10501 ctgcgtcttt tgcctacccc tcccgccgtc tacctctccg gcgatattcg ctttcacggc
    10561 gaatcattgc ttcatgccag cgagcagacg ctacgcggcg tacgcggcaa taaaatcgcc
    10621 atgatttttc aggaaccgat ggtttcactt aacccactgc atacgctgga aaaacagctc
    10681 tatgaagtgc tgtcgctcca tcggggaatg cgtcgggagg cggcaagggc ggagatgatc
    10741 ggttgtctgg atcgggtcgg tatccgccag gcgagccagc gtctgcgcga ttatccgcat
    10801 cagctttccg gcggcgaacg ccagcgcgtc atgatagcca tggcgctgtt aacacggccg
    10861 gaattactga tcgccgatga gccgaccacc gccctcgacg tctccgtaca ggcgcagatc
    10921 ttatctctac tgcgggaact ccagcgtgag ctcaatatgg gattgctgtt tatcacccat
    10981 aacctcagca ttgtaaaaaa actggcggat tcagtggcgg taatgcaaca cggcaagtgc
    11041 gtagagaacc aacgcgccga cacgctgctc tccgcgccga cccatccgta cacgcaaaaa
    11101 ctactcaaca gcgaacccac tggcgatccg gttccgctcc ccgccgggca ggcgccgttg
    11161 ctggaagtgg acaagctgcg cgtcgccttc ccaatccgca aaggcattct gaagcgcgtc
    11221 gtggatcata atgtggtggt taacaatatc agtttcaccc tgcatccagg cgaaacgctg
    11281 ggtctggtcg gcgagtcagg atcgggaaaa agcaccaccg gtctggcgct gttacggctt
    11341 atccgctccg aaggccgcat cgtgtttgac ggtcaatcgc tggatacgtt aaaccgccgc
    11401 cagcttttac ctgttcgcca ccgtatccag gtcgtattcc aggacccgaa ctcatcgcta
    11461 aacccgcgtt taaacgtatt gcaaattatc gaagaaggcc tgcgcgtcca ccagcctacg
    11521 ctttcaggcg cgcagcgcga acagcaggtg aaagcggtca tgatggaagt cggcctggac
    11581 ccggaaacgc ggcatcgtta ccccgctgag ttttccggcg gccagcgtca acgtatcgcc
    11641 gtcgccaggg cgctgatttt aaaaccgtcg cttattattc tggatgaacc gacctcatcg
    11701 ctggataaaa ccgttcaggc gcagattctt gccctcctga aatcgctcca gcaaaagcac
    11761 cgtctggcct atatcttcat tagccacgat ctgcatgtag tacgcgcgct gtgccatcag
    11821 gttatcgtgc tgcgacaggg ggaggtggtt gaacaggggc aatgcgagcg cgtgtttacc
    11881 gcaccgcaac aagcgtatac gcgtcagcta ctcgcgttaa gctgacgcct aaaaaggatt
    11941 attgttagaa aaaggttccg ctatcgccac gccgaaattt ttcagccgac aggtggcggc
    12001 aaactcatcc tgacgattaa cgaacaggca cggttcccct tcgcactcca gcacggagca
    12061 aggaacttca atatcgctta gcgcctggct gagcttatgc atcactgacc acgcgctatc
    12121 gcctgccgga ctcaacagtt taagcgccac cagactattc tcggtgctct gcccgttttg
    12181 cggaatcggt tcaacctttg accccgcaaa acccgccgac cagcgatagt tttgcggcag
    12241 acggtgaaca attgagagct gtaatgtatt cactttcttt ccccggaagc acaattactt
    12301 cacaatttac ttacatttat attaacacat cattgacaac ccgtccttaa acagattgct
    12361 a
//
LOCUS       DAJVBX010000141        12198 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.141, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000141 DAJVBX010000000
VERSION     DAJVBX010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 12198)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12198)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12198
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.141"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..260
                     /locus_tag="OPV72_003214"
     CDS             <1..260
                     /locus_tag="OPV72_003214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_448379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915435.1"
                     /translation="IARCLADNLSPYGYILDLHETDIPGISKEFTVYYRNGAYIAGTF
                     WIANSMTIASELIVGMNGVSKQAYPIFNKSLQQCATRLSIK"
     gene            complement(380..694)
                     /gene="fliE"
                     /locus_tag="OPV72_003215"
     CDS             complement(380..694)
                     /gene="fliE"
                     /locus_tag="OPV72_003215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein FliE"
                     /protein_id="HCR9915436.1"
                     /translation="MAAIQGIEGGISQLQATAMAANGQETHSQSTVSFAGQLHAALDR
                     ISDRQTAARVQAEKFTLGEPGIALNDVMADMQKASVSMQMGIQVRNKLVAAYQEVMSM
                     QV"
     gene            911..2593
                     /gene="fliF"
                     /locus_tag="OPV72_003216"
     CDS             911..2593
                     /gene="fliF"
                     /locus_tag="OPV72_003216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar M-ring protein FliF"
                     /protein_id="HCR9915437.1"
                     /translation="MSATASTATQPKPLEWLNRLRANPRIPLIVAGSAAVAIVVAMVL
                     WAKTPDYRTLFSNLSDQDGGAIVAQLTQMNIPYRFANGSGAIEVPADKVHELRLRLAQ
                     QGLPKGGAVGFELLDQEKFGISQFSEQVNYQRALEGELARTIETLGPVKSARVHLAMP
                     KPSLFVREQKSPSASVTVTLEPGRALDEGQISAVVHLVSSAVAGLPPGNVTLVDQSGH
                     LLTQSNTSGRDLNDAQLKFANDVESRIQRRIEAILSPIVGNGNVHAQVTAQLDFANKE
                     QTEEHYSPNGDASKATLRSRQLNISEQVGAGYPGGVPGALSNQPAPPNEAPIATPPTN
                     QQNAQNTPQTSTSTNSNNAGPRNTQRNETSNYEVDRTIRHTKMNVGDIERLSVAVVVN
                     YKTLADGKPLPLTADQMKQIEDLTREAMGFSDKRGDTLNVVNSPFSAVDNTGGELPFW
                     QQQSFIDQLLAAGRWLLVLVVAWILWRKAVHPQLTRRVEEAKAAQEQAQVRQETEEAV
                     EVRLSKDEQLQQRRANQRLGAEVMSQRIREMSDNDPRVVALVIRQWMSNDHE"
     gene            2586..3581
                     /gene="fliG"
                     /locus_tag="OPV72_003217"
     CDS             2586..3581
                     /gene="fliG"
                     /locus_tag="OPV72_003217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliG"
                     /protein_id="HCR9915438.1"
                     /translation="MSNLSGTDKSVILLMTIGEDRAAEVFKHLSTREVQALSTAMANV
                     RQISNKQLTDVLSEFEQEAEQFAALNINANEYLRSVLVKALGEERASSLLEDILETRD
                     TTSGIETLNFMEPQSAADLIRDEHPQIIATILVHLKRSQAADILALFDERLRHDVMLR
                     IATFGGVQPAALAELTEVLNGLLDGQNLKRSKMGGVRTAAEIINLMKTQQEEAVITAV
                     REFDGELAQKIIDEMFLFENLVDVDDRSIQRLLQEVDSESLLIALKGAEPPLREKFLR
                     NMSQRAADILRDDLANRGPVRLSQVENEQKAILLIVRRLAETGEMVIGSGEDTYV"
     gene            3574..4281
                     /gene="fliH"
                     /locus_tag="OPV72_003218"
     CDS             3574..4281
                     /gene="fliH"
                     /locus_tag="OPV72_003218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliH"
                     /protein_id="HCR9915439.1"
                     /translation="MSNELPWQVWTPDDLAPPPETFVPVEADNVTLTDDTPEPELTAE
                     QQLEQELAQLKIQAHEQGYNAGLAEGRQKGHAQGYQEGLAQGLEQGQAQAQTQQAPIH
                     ARMQQLVSEFQNTLDALDSVIASRLMQMALEAARQVIGQTPAVDNSALIKQIQQLLQQ
                     EPLFSGKPQLRVHPDDLQRVEEMLGATLSLHGWRLRGDPTLHHGGCKVSADEGDLDAS
                     VATRWQELCRLAAPGVL"
     gene            4281..5651
                     /gene="fliI"
                     /locus_tag="OPV72_003219"
     CDS             4281..5651
                     /gene="fliI"
                     /locus_tag="OPV72_003219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellum-specific ATP synthase FliI"
                     /protein_id="HCR9915440.1"
                     /translation="MTTRLTRWLTALDNFEAKMALLPAVRRYGRLTRATGLVLEATGL
                     QLPLGATCIIERQDGPETKEVESEVVGFNGQRLFLMPLEEVEGILPGARVYARNGHGD
                     GLQSGKQLPLGPALLGRVLDGGGKPLDGLPAPDTLETGALITPPFNPLQRTPIEHVLE
                     TGVRAINALLTVGRGQRMGLFAGSGVGKSVLLGMMARYTRADVIVVGLIGERGREVKD
                     FIENILGPDGRARSVVIAAPADVSPLLRMQGAAYATRIAEDFRDRGQHVLLIMDSLTR
                     YAMAQREIALAIGEPPATKGYPPSVFAKLPALVERAGNGIHGGGSITAFYTVLTEGDD
                     QQDPIADSARAILDGHIVLSRRLAEAGHYPAIDIEASISRAMTALITEQHYARVRLFK
                     QLLSSFQRNRDLISVGAYAKGSDPMLDKAITLWPQLEAFLQQGIFERADWEDSLQALD
                     LIFPTV"
     gene            5673..6116
                     /gene="fliJ"
                     /locus_tag="OPV72_003220"
     CDS             5673..6116
                     /gene="fliJ"
                     /locus_tag="OPV72_003220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis chaperone FliJ"
                     /protein_id="HCR9915441.1"
                     /translation="MAQHGALETLKDLAEKEVDDAARLLGEMRRGCQQAEEQLKMLID
                     YQNEYRSNLNTDMGNGIASNRWINYQQFIQTLEKAIEQHRLQLTQWTQKVDLALKSWR
                     EKKQRLQAWQTLQDRQTAAALLAENRMDQKKMDEFAQRAAMRKPE"
     gene            6113..7342
                     /gene="fliK"
                     /locus_tag="OPV72_003221"
     CDS             6113..7342
                     /gene="fliK"
                     /locus_tag="OPV72_003221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook length control protein FliK"
                     /protein_id="HCR9915442.1"
                     /translation="MITLPQLITTDTDMTAGLTSGKTTGSAEDFLALLAGALGADGAQ
                     GKDARITLADLQAAGGKLSKELLAQHGEPGQAVKLADLLAQKANATDETLTNLTQAQH
                     LLSTLTPSLKTSALAALSKTAQHDEKTPALSDEDLASLSALFAMLPGQPVATPVAGET
                     PAENHIALPSLLRGDMLSAPQEETHTLSFSEHEKGKTEASLARASDDRAMGPSLTPLV
                     VAAAATSAKVEVEVDSPSAPVTHGAAMPTLSSATAQPQPLPVASAPVLSAPLGSHEWQ
                     QTFSQQVMLFTRQGQQSAQLRLHPEELGQVHISLKLDDNQAQLQMVSPHSHVRAALEA
                     ALPMLRTQLAESGIQLGQSSISSESFAGQQQSSSQQQSARAQHTDAFGAEDDIALAAP
                     ASLQAAARGNGAVDIFA"
     gene            7447..7914
                     /gene="fliL"
                     /locus_tag="OPV72_003222"
     CDS             7447..7914
                     /gene="fliL"
                     /locus_tag="OPV72_003222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body-associated protein FliL"
                     /protein_id="HCR9915443.1"
                     /translation="MTDSAINKKSKRSIWIPLLVLITLAACATAGYSYWRMQQQPTTN
                     AKAEPAPPPAPVFFVLDTFTVNLGDADRVLYIGVTLRLKDEATRARLNEYLPEVRSRL
                     LLLFSRQNAAELSTEAGKQKLIAAIKETLAAPLVAGQPKQVVTDVLYTAFILR"
     gene            7919..8923
                     /gene="fliM"
                     /locus_tag="OPV72_003223"
     CDS             7919..8923
                     /gene="fliM"
                     /locus_tag="OPV72_003223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliM"
                     /protein_id="HCR9915444.1"
                     /translation="MGDSILSQAEIDALLNGDSDTKDEPTPGIASDSDIRPYDPNTQR
                     RVVRERLQALEIINERFARQFRMGLFNLLRRSPDITVGAIRIQPYHEFARNLPVPTNL
                     NLIHLKPLRGTGLVVFSPSLVFITVDNLFGGDGRFPTKVEGREFTHTEQRVINRMLKL
                     ALEGYSDAWKAINPLEVEYVRSEMQVKFTNITTSPNDIVVNTPFHVEIGNLTGEFNIC
                     LPFSMIEPLRELLVNPPLENSRHEDQNWRDNLVRQVQHSELELVANFADIPLRLSQIL
                     KLKPGDVLPIEKPDRIIAHVDGVPVLTSQYGTVNGQYALRVEHLINPILNSLNEEQPK
                     "
     gene            8920..9333
                     /gene="fliN"
                     /locus_tag="OPV72_003224"
     CDS             8920..9333
                     /gene="fliN"
                     /locus_tag="OPV72_003224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliN"
                     /protein_id="HCR9915445.1"
                     /translation="MSDMNNPSDENTGALDDLWADALNEKKATTNKSAADAVFQQLGG
                     GDVSGAMQDIDLIMDIPVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILIN
                     GYLIAQGEVVVVADKYGVRITDIITPSERMRRLSR"
     gene            9333..9710
                     /gene="fliO"
                     /locus_tag="OPV72_003225"
     CDS             9333..9710
                     /gene="fliO"
                     /locus_tag="OPV72_003225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460931.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system protein
                     FliO"
                     /protein_id="HCR9915446.1"
                     /translation="MMKTEATVSQPTAPAGSPLMQVSGALIGIIALILAAAWVIKRMG
                     FAPKGNSVRGLKVSASASLGPRERVVIVEVENARLVLGVTASQINLLHTLPPAENDTE
                     APVAPPADFQNMMKSLLKRSGRS"
     gene            9710..10447
                     /gene="fliP"
                     /locus_tag="OPV72_003226"
     CDS             9710..10447
                     /gene="fliP"
                     /locus_tag="OPV72_003226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460932.1"
                     /note="The bacterial flagellar biogenesis protein FliP
                     forms a type III secretion system (T3SS)-type pore
                     required for flagellar assembly; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system pore protein
                     FliP"
                     /protein_id="HCR9915447.1"
                     /translation="MRRLLFLSLAGLWLFSPAAAAQLPGLISQPLAGGGQSWSLSVQT
                     LVFITSLTFLPAILLMMTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMS
                     PVIDKIYVDAYQPFSEQKISMQEALDKGAQPLRAFMLRQTREADLALFARLANSGPLQ
                     GPEAVPMRILLPAYVTSELKTAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIA
                     LPFKLMLFVLVDGWQLLVGSLAQSFYS"
     gene            10457..10726
                     /gene="fliQ"
                     /locus_tag="OPV72_003227"
     CDS             10457..10726
                     /gene="fliQ"
                     /locus_tag="OPV72_003227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013365797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliQ"
                     /protein_id="HCR9915448.1"
                     /translation="MTPESVMMMGTEAMKVALALAAPLLLVALITGLIISILQAATQI
                     NEMTLSFIPKIVAVFIAIIVAGPWMLNLLLDYVRTLFSNLPYIIG"
     gene            10735..11529
                     /gene="fliR"
                     /locus_tag="OPV72_003228"
     CDS             10735..11529
                     /gene="fliR"
                     /locus_tag="OPV72_003228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system protein
                     FliR"
                     /protein_id="HCR9915449.1"
                     /translation="MIQVISEQWLYWLHLYFWPLLRVLALISTAPILSERAIPKRVKL
                     GLGIMITLVIAPSLPANDTPLFSIAALWLAMQQILIGIALGFTMQFAFAAVRTAGEFI
                     GLQMGLSFATFVDPGSHLNMPVLARIMDMLAMLLFLTFNGHLWLISLLVDTFHTLPIG
                     SNPVNSNAFMALARAGGLIFLNGLMLALPVITLLLTLNLALGLLNRMAPQLSIFVIGF
                     PLTLTVGIMLMAALMPLIAPFCEHLFSEIFNLLADIVSEMPINNNP"
     gene            11811..>12198
                     /gene="rcsA"
                     /locus_tag="OPV72_003229"
     CDS             11811..>12198
                     /gene="rcsA"
                     /locus_tag="OPV72_003229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RcsA"
                     /protein_id="HCR9915450.1"
                     /translation="MSTIIMDLCSYTRLGLSGYLVSRGVKKREINDIETVDELAIACG
                     AHQPSVVFINEDCFIHTPSDSQQIKQIINQHPDTLFIVFMAIANVHFDEYLLVRKNLL
                     ISSKSIKPDSLDTLLGDILKKESGISG"
BASE COUNT         2830 a         3320 c         3370 g         2678 t
ORIGIN      
        1 ccattgcccg ctgtctcgct gataatctgt ccccgtatgg gtatatactg gatctccatg
       61 aaacagatat tccaggtatt agtaaagaat ttaccgtgta ttatcgcaac ggcgcatata
      121 ttgcaggaac attctggatt gcaaactcaa tgacaatagc ctcagaacta atagtaggaa
      181 tgaatggcgt cagtaaacag gcgtacccta tttttaataa gtccctgcaa caatgtgcaa
      241 cccgcttatc aataaaatga gcgcgcctcg caaaaacaag cccacataat cacgcactgg
      301 ttgcatgggc gtcgcgtccc ccgccactga cttaggtaag cgcccgggag ttcgctgcgg
      361 atgtgttgtc agccctggct taaacctgca tggacatgac ttcctgatac gcggcgacca
      421 gcttattgcg cacctgaatc cccatttgca tagagacgga cgctttttgc atatcagcca
      481 tcacgtcatt aagcgcaatg cccggctcac ccagagtgaa tttttccgcc tgaacgcgcg
      541 ccgccgtttg tctgtcgcta atacgatcca gcgcagcatg tagctggccg gcaaaactca
      601 ccgtcgactg cgagtgtgtt tcttgcccgt ttgcggccat cgccgtcgcc tgtaactggc
      661 taataccccc ttcaatcccc tgtattgctg ccatgttatt cccctggatg attttttacg
      721 cagcagagat taccagtttg tcaataagat aaaggcgtta aataacgata aaaaacctcg
      781 gtttttagcg catagaaaaa ttcgaaacca caaataatga gaccgtcaat ttttcgagtt
      841 tgctgacccg ggagtgagtc ttgttccact ttgcaaaaaa cgccgtccac gatcagtcac
      901 gaggtgcgag atgagtgcga ctgcatcgac tgcaacccaa cctaaacctc tcgagtggct
      961 taatcgccta cgcgcgaatc cccgaattcc gttaattgtg gcgggttccg ccgccgtggc
     1021 gatcgtcgtt gcgatggtgc tgtgggccaa aacgcccgat taccgcacgc tatttagcaa
     1081 cctttccgat caggacggcg gcgcgatcgt cgcgcagttg acccagatga atatccccta
     1141 tcgctttgcc aatggcagcg gcgcgattga agtgcccgcc gacaaagtgc atgaactgcg
     1201 tctgcgtctg gcgcagcagg ggctgcctaa aggcggcgcg gtaggctttg aactgcttga
     1261 tcaggaaaaa ttcggtatca gtcagttcag cgagcaggtg aattatcagc gcgcgctgga
     1321 aggtgaactg gcccggacga tcgagacgct gggtccggta aaaagcgccc gcgttcacct
     1381 ggcgatgcca aagccgtcgc tatttgtgcg ggaacaaaaa tccccttccg cctccgtcac
     1441 cgtcacactg gaaccgggcc gggcgctgga tgaaggacaa attagcgccg tggtacatct
     1501 ggtttccagc gctgtcgccg gtttgccgcc aggaaacgtc actctggtcg atcaatccgg
     1561 tcatctgctc acgcaatcca ataccagcgg tcgcgacctt aatgacgcgc aattaaaatt
     1621 tgctaatgat gtggaaagcc gcatccaacg ccgtatcgaa gccattctgt cgcctatcgt
     1681 cgggaacggt aatgttcacg ctcaggtaac cgcccagttg gattttgcca ataaagaaca
     1741 gacggaagag cactacagcc cgaacggcga tgcgtcgaag gccactctgc gttcacgtca
     1801 gttgaatatt agcgaacagg taggcgcggg ctatcccggc ggcgtgcctg gcgcgctgtc
     1861 gaaccaacca gcgccgccta acgaggcgcc gatcgccaca ccgccgacca atcaacaaaa
     1921 cgcgcagaat acgccacaaa ccagcaccag taccaacagt aacaacgctg gcccgcgcaa
     1981 tacgcagcgt aatgaaacca gtaactacga agtggaccgc accattcgtc acaccaaaat
     2041 gaatgtgggc gatattgagc gtctctctgt agctgtcgtg gtgaattaca aaacgctggc
     2101 ggatggcaaa ccgctgccat tgaccgccga tcagatgaaa cagatcgagg atttaacccg
     2161 tgaagcgatg ggtttttctg ataaacgcgg cgatacgcta aacgtggtga attcaccgtt
     2221 tagcgcagtg gataacaccg gcggcgaact gcccttctgg caacagcagt cctttatcga
     2281 tcagttgctc gcggcaggtc gctggttact ggtgctggtg gtggcctgga ttctgtggcg
     2341 caaagcggta catccacagt tgacgcgccg cgttgaagaa gcgaaagcgg cgcaggaaca
     2401 ggcgcaggtt cgccaggaaa ccgaagaagc cgtggaagta cgccttagca aagacgagca
     2461 gctccagcaa cgccgggcta accagcgtct gggcgctgag gtgatgagcc agcgtattcg
     2521 cgaaatgtca gacaacgatc cgcgcgtggt ggcgctggtc attcgccagt ggatgagtaa
     2581 cgatcatgag taatcttagc ggtaccgata aaagcgtcat tttgttgatg accattggcg
     2641 aagaccgggc ggcagaggtg tttaaacacc tctccacccg cgaagtacag gcgttaagta
     2701 cggcgatggc taacgtgcgt cagatctcca acaaacaact gacggacgta ctatcagagt
     2761 ttgagcaaga agcggagcag ttcgccgcgc tgaatatcaa cgccaacgaa tacctgcgct
     2821 ccgtactggt taaagcgctg ggcgaagaac gcgcctccag cctgctggaa gatattctgg
     2881 aaacgcgcga taccaccagc ggtatcgaaa cgctcaactt tatggaaccg cagagcgccg
     2941 ccgacctgat tcgcgacgaa cacccgcaga ttatcgccac cattctggtc cacctcaaac
     3001 gcagtcaggc cgccgatatt ctggcactgt ttgacgaacg actgcgtcat gatgtgatgc
     3061 tgcgtatcgc gacatttggc ggcgtacagc cggcggcgct ggcggagttg accgaagtgc
     3121 tgaatggcct gctcgacggt cagaacctga aacgcagcaa aatgggcggc gtaagaaccg
     3181 cggcagaaat tatcaacctg atgaaaacgc agcaggaaga agcggttatt accgctgtgc
     3241 gcgaattcga cggcgaactg gcgcagaaaa tcatcgacga gatgttcctg ttcgaaaatc
     3301 tggtggatgt ggacgatcgc agtatccaac gtctgctgca ggaagtggat tccgagtcgc
     3361 tgctgatcgc tctgaaaggc gccgaaccgc cattacgcga gaagttcctg cgcaatatgt
     3421 cccagcgcgc cgccgatatc ctgcgcgacg accttgccaa ccgtggcccg gttcgtctgt
     3481 ctcaggtgga aaacgagcag aaagcgattc tgcttattgt gcgtcgtctg gcggaaaccg
     3541 gcgaaatggt gattggcagc ggcgaggata cctatgtcta atgaattgcc gtggcaagtc
     3601 tggacccccg acgatctcgc tccgccgccg gagacgtttg tgccggttga ggctgataac
     3661 gttaccttga cagacgatac gccggagccc gaactcactg ccgaacagca gctggagcag
     3721 gagctggcgc agctaaaaat acaggcccat gaacaaggtt ataacgccgg gctggcggag
     3781 ggacggcaaa aaggacacgc gcagggatac caggaagggt tagcgcaagg gctggagcaa
     3841 ggacaagccc aggcgcagac gcagcaggcg ccgattcatg cccgtatgca gcagttagtg
     3901 agcgagtttc agaacacgct tgacgcgctc gatagcgtta tcgcctcacg gctgatgcaa
     3961 atggccctgg aggccgcacg tcaggtcatc ggccaaacgc cggcggtgga caactcagcg
     4021 ctgattaaac agatccaaca actgttgcag caagagccgc tctttagcgg caagccgcag
     4081 ttgcgcgtgc atccggacga cttacagcgg gtggaagaga tgctgggcgc cacgctcagt
     4141 cttcacggat ggcggttgcg cggcgatcca acgttgcatc acggcgggtg taaagtctct
     4201 gccgatgagg gcgatctgga cgccagcgtc gccactcgct ggcaagagtt gtgtcgcctg
     4261 gcggcgccgg gagtgctctg atgaccacgc gcctgacccg ctggcttacc gcgctcgaca
     4321 actttgaagc aaaaatggcg ttattgccgg cggtgcgccg ttatggacgt ttaacccgcg
     4381 ccactggcct ggtactggag gccaccggtc tccagcttcc gctgggcgcc acctgcatta
     4441 ttgagcgcca ggacggccct gaaaccaaag aggtggaatc ggaagtcgtc ggttttaacg
     4501 gccagcgtct gtttttaatg ccgctggaag aggtcgaagg cattctgccc ggtgcccgcg
     4561 tttacgcccg taacgggcat ggcgacggtc tgcaaagcgg caaacagtta ccgctcggcc
     4621 cggccctgct tggtcgggtg ctggatggcg gcggtaaacc gctcgacgga ctgcctgcgc
     4681 cggatacgct ggaaaccggc gcgttaatca cgccgccgtt taacccgcta cagcgaacgc
     4741 caatcgaaca tgtgctggaa accggcgtac gcgccatcaa cgcgttgtta accgtagggc
     4801 gcggtcagcg tatgggactc tttgccggtt ccggcgtcgg taaatcggtt ctgcttggca
     4861 tgatggcgcg ctacacacgg gcggacgtga ttgtcgtggg tcttatcggc gaacgtggcc
     4921 gcgaagttaa agattttatc gaaaatattc tcggccccga cggtcgcgcg cgttcggtgg
     4981 tgatcgccgc cccggcggat gtttcgccgc tgctgcgaat gcagggcgcc gcctatgcca
     5041 cccgcatcgc cgaagacttt cgcgatcgcg gacagcatgt gttgctgatt atggattcgc
     5101 tgacgcgcta tgcgatggcg cagcgtgaaa ttgccctggc aatcggcgaa ccgccagcca
     5161 ccaaaggtta tccgccctcg gtgttcgcaa agctgccagc gctggtcgag cgtgccggta
     5221 atggcatcca cggcggcggc tctatcaccg cgttttatac cgtattgacc gagggggacg
     5281 accaacaaga tcccattgcc gactcggcac gcgcaatcct cgacgggcac attgtcttgt
     5341 cccgccgcct ggcggaagcc gggcactacc cggccattga tatcgaggcg tcaatcagcc
     5401 gggcgatgac cgcgctcatt accgagcagc actatgcgcg ggtacggcta tttaaacaat
     5461 tgctttccag tttccagcgt aaccgcgatc tgatcagcgt cggcgcctat gccaaaggca
     5521 gcgatccgat gctcgataaa gccattacct tatggccgca attagaagcg tttttacagc
     5581 aaggcatttt tgaacgggcc gactgggagg actctcttca ggcgctcgat ttaattttcc
     5641 cgacggtgtg ataaatcagg agggcgacga tcatggcaca acatggcgct ctggaaacac
     5701 tcaaagatct ggccgaaaaa gaggtagatg acgcggcgcg tttactgggc gaaatgcgtc
     5761 gcggctgcca acaggcggaa gaacagctca aaatgctgat cgattatcag aatgagtatc
     5821 gcagtaattt gaacaccgat atgggcaacg gcatcgccag taatcgctgg atcaactatc
     5881 agcagtttat tcagacactg gaaaaggcga tagagcagca tcgcctccag cttacgcagt
     5941 ggacgcaaaa agtcgacctg gcgctgaaga gctggcgtga gaaaaagcag cgacttcagg
     6001 cctggcaaac cttacaggac cgacaaaccg cggcagcgct gttagctgaa aaccgcatgg
     6061 atcagaaaaa gatggatgaa tttgctcagc gtgcagcaat gaggaaaccc gaatgatcac
     6121 cctgccccaa ctgatcacca ccgataccga catgaccgcg ggtctgacgt caggaaaaac
     6181 caccggttca gccgaggact ttctggcgct cctggcgggc gcgttaggcg cagacggcgc
     6241 acagggcaaa gacgcccgca tcacgctggc cgatttacag gcggcaggcg gcaagttatc
     6301 gaaagagcta ctggcccaac atggcgagcc gggccaggcg gtgaagcttg ccgacctgct
     6361 ggcgcaaaaa gcgaatgcga cggatgaaac gcttaccaat ctgacacaag cgcagcatct
     6421 actgtctacg ctaacgccat cgttgaaaac cagcgctctg gccgcattga gtaaaacggc
     6481 gcagcatgat gagaaaacgc ccgcgctgag cgatgaggat cttgccagtc tgagcgcctt
     6541 attcgccatg ctgcccggac aacctgtcgc gacgcctgtc gccggagaaa cgccggctga
     6601 aaatcacatc gccttgccgt cactgttacg cggcgacatg ctatcggcgc cgcaggaaga
     6661 gacacatacg ctctctttta gcgagcatga aaaagggaaa accgaggcgt cgcttgcgcg
     6721 cgccagcgac gatcgcgcca tggggccatc actgacgccg ctggtggtcg ctgccgccgc
     6781 gaccagcgcg aaagtggagg tggaggtgga tagcccgtcc gcgccagtaa cgcatggcgc
     6841 ggcaatgccg acgctcagca gcgccacggc gcaaccgcaa ccgctacctg tcgcctcagc
     6901 cccggtactc agcgcgccgt taggcagcca tgaatggcaa caaacgttca gtcagcaggt
     6961 catgttattt acgcgtcagg gacagcaaag cgcgcagctt cgattgcatc cggaagagtt
     7021 aggtcaggtg cacatttcgc tcaagctgga tgacaatcag gcgcagctcc agatggtatc
     7081 gccgcacagc catgtccgcg ccgcgctgga agccgccctg cccatgttac gcacccagtt
     7141 ggcggaaagc ggcattcagt tgggacaaag tagtatcagt agcgaaagct ttgccggaca
     7201 gcagcagtct tcatcgcaac aacagtctgc ccgcgcccaa cacacagacg cgtttggcgc
     7261 tgaagatgat atagcgttag cggcgccggc ctcgcttcag gccgccgcgc gcggcaatgg
     7321 cgcagtggat atcttcgcct aacgccagag gtagcatgat tatccgcgtc ttttccacgc
     7381 tttgtcgtgg acaggacacg ggataatcag ccaataagca gtaccgaaac aggaagcccg
     7441 tatcagatga ctgactccgc gattaacaaa aagagcaaac gctcgatttg gatacctttg
     7501 ctggtgttga ttaccctcgc cgcctgcgcg actgccggtt atagctactg gcgtatgcag
     7561 cagcaaccga ccacgaacgc taaagcggaa ccggctccgc cgcccgcgcc ggtatttttt
     7621 gtgctggata cgtttaccgt caatctgggc gatgcggatc gcgtgttgta tatcggcgtg
     7681 accctgcgtc tgaaagacga agcgacgcgc gcacgattaa atgaatatct gccggaagtg
     7741 cgcagccgtc tgctgttgtt attttcccgt cagaatgccg ccgagctctc aacagaagct
     7801 ggcaaacaaa aactgattgc cgccattaaa gagacgctgg ccgcgccgct cgttgccgga
     7861 caaccaaaac aggtcgtcac tgacgtgctt tatacagctt ttattctgcg gtaacgatat
     7921 gggcgatagt attctttctc aggctgaaat cgatgcgctg ttgaacggcg acagcgacac
     7981 caaagacgaa cccactcccg gtatcgcaag cgatagcgat attcgccctt acgatcccaa
     8041 tacccagcgt cgcgtcgtgc gtgaacgctt gcaggcgctg gagattatta acgagcgttt
     8101 cgcacgccag ttccggatgg gattatttaa cctgctgcgc cgcagcccgg atattaccgt
     8161 gggcgccata cgtattcagc cgtatcacga atttgcgcgt aacctgccag taccgaccaa
     8221 cctgaacctg atccacctga agccgctacg cggcaccggg ctggtggtgt tctcgccgag
     8281 tctggtgttt attaccgtcg ataacctgtt cggcggcgac ggtcgttttc cgaccaaagt
     8341 cgagggccgc gagtttaccc atacggaaca gcgggtcatc aaccgtatgc tgaaactggc
     8401 gctggaaggc tatagcgacg catggaaagc cattaatccg ctggaagtgg agtatgtgcg
     8461 ttccgaaatg caggtgaaat ttaccaatat caccacctcg ccgaacgata tcgtcgtcaa
     8521 tacgccgttt catgtggaga tcggcaatct gaccggtgaa tttaacatct gtctgccatt
     8581 tagcatgatc gagccgctgc gtgagctgct ggtgaatccg ccgctggaaa actcgcgcca
     8641 tgaagatcag aactggcgtg ataacctggt gcgccaggtt cagcactctg aactggagct
     8701 ggtggccaat tttgccgata ttccgttacg tctttcccag attttgaagc tgaaacccgg
     8761 cgatgtactg ccgattgaaa aacccgaccg cattattgct catgtggacg gcgttccggt
     8821 actcaccagc caatatggca ccgtaaacgg acagtatgcg ctacgcgtag aacatttgat
     8881 caacccaatt ttgaattcgc tgaatgagga acagcccaaa tgagtgacat gaataatccg
     8941 tccgatgaga atactggcgc attggatgat ctgtgggctg acgcgttaaa cgagaaaaaa
     9001 gcgaccacca ataaaagcgc cgccgacgcg gttttccaac agcttggcgg cggcgatgtc
     9061 agcggtgcta tgcaggatat cgatctgatt atggatatcc cggtcaaact gaccgtagag
     9121 ctgggccgca cgcgaatgac cattaaagaa ctgctgcgtc tgacgcaggg gtcggtcgtc
     9181 gcgctggacg ggctggcggg cgagccgctg gacatcctga ttaatggcta cctgattgcc
     9241 cagggtgaag tggtcgtcgt ggcggataaa tacggcgtac gtatcaccga tattattacg
     9301 ccatccgagc gtatgcgtcg tttgagtcgt taatgatgaa gacagaggcc acggtttctc
     9361 agcccaccgc gccagccgga tcgccgctca tgcaggtgag cggcgcatta attggcatta
     9421 ttgcgctcat tctggcggcg gcctgggtga ttaagcgtat gggattcgcg ccaaaaggaa
     9481 atagcgtccg gggactgaag gtgtcagcca gcgcctcgct tggcccgcgc gaacgcgtgg
     9541 tgattgtcga ggtcgaaaat gcgcgcctgg tactgggcgt gaccgcctcg cagatcaacc
     9601 tgctgcacac cctcccgccc gcggagaatg acacggaagc acccgttgcc ccaccggcgg
     9661 atttccagaa catgatgaag agcttactca agcgttccgg gagatcctga tgcgccgttt
     9721 gttattcctt tctctggcgg gtctgtggct ttttagtccc gccgccgctg cgcaactgcc
     9781 ggggcttatc agccaaccat tagcgggcgg aggccaaagc tggtcattat ccgtccagac
     9841 gctggttttc atcacctcgc tgacgtttct gccggcgatt ttactgatga tgacgagctt
     9901 cacgcgtatc atcattgttt ttggcttgtt gcgtaacgcg ctgggcacgc cctcggcacc
     9961 gccaaatcag gtgttactcg gactggcgtt gtttttgacc ttttttatta tgtcgcccgt
    10021 cattgacaag atttacgtgg atgcttacca gccgtttagc gagcagaaaa tttctatgca
    10081 ggaagcgctg gataaaggcg cgcaaccgtt acgcgcgttc atgctgcgcc aaacccgcga
    10141 agccgatctg gcgctgtttg cccgtctggc caatagcggt ccgttacagg gaccggaagc
    10201 agtaccgatg cgtatcctcc tgcccgctta tgtcaccagc gaattaaaga cggcgtttca
    10261 gatcggtttt acgattttca tccctttttt gattatcgac ctggtgatcg ccagcgtact
    10321 gatggcgtta gggatgatga tggtgccgcc agcgacaatc gccctgccgt ttaagctgat
    10381 gctgtttgtg ctggtcgatg gttggcaatt gcttgtgggg tcgctggccc aaagctttta
    10441 cagttagagg cgcaaaatga ctcctgaatc cgtcatgatg atggggaccg aggcgatgaa
    10501 agttgctctc gccctggctg cgccgctgtt actcgtcgcg ctgattaccg gcctcattat
    10561 cagcatcttg caggccgcga ctcagattaa tgaaatgacg ctgtcgttta tccctaaaat
    10621 cgtcgcggta ttcatcgcaa ttatcgttgc cggcccgtgg atgctcaacc tgctgctgga
    10681 ctacgtacgc actctgttca gcaatttacc ttatatcatc ggataaacag aacgatgata
    10741 caggttataa gcgagcaatg gctatactgg ctgcatctct atttctggcc tttgctgcgc
    10801 gtactggcgc tgatttcaac ggcgcccatt ctcagcgagc gcgctattcc caagcgggta
    10861 aaactggggt tgggaataat gattaccctc gttatcgcgc cgtcgctacc agcaaacgat
    10921 acgccgcttt tttctattgc cgccttatgg ctggcgatgc aacaaattct gatcggtatt
    10981 gcgctgggat ttaccatgca attcgccttt gcggcggtgc gtaccgcagg tgagtttatc
    11041 ggtctgcaaa tggggctttc ctttgccacc ttcgtcgacc cgggcagcca cttgaatatg
    11101 ccggttctgg cgcgtattat ggatatgctc gccatgctac tgtttctcac ctttaatggc
    11161 catttgtggc ttatttcgct gctggtcgat accttccata ctctgcccat cggtagtaac
    11221 ccggtgaaca gtaatgcatt tatggcgctc gccagggccg gagggctcat tttcttaaac
    11281 ggactgatgc tggcattgcc ggtcattacc ctcctgctta cgctcaacct ggcgctgggg
    11341 ctattaaacc gcatggcgcc gcagctctcg atatttgtta tcggtttccc gcttaccctc
    11401 accgtcggca ttatgctgat ggccgcgcta atgccattaa ttgcgccgtt ttgcgaacat
    11461 ttattcagcg aaattttcaa tttgcttgct gatattgtta gcgagatgcc gataaataat
    11521 aacccataat ttttatcctg ttttactaag gtttatccga aaataaattt taaaaaacat
    11581 tcaccaggat atatccgctg ccccttattt gtttttactt cactcacata acgcaacatt
    11641 cactttactt taagatgatt cctggcaaat tatatgtaac tttacgggat agtaagttcg
    11701 cctgaaaaac cgcgtaagcg ttgtctaagg tgactattcg tgttccgtct gattatggtg
    11761 agttattcag gtaaggggaa ttatcgttac gcattgagtg agggtatgcc atgtcaacga
    11821 ttattatgga tttatgcagt tacacccggc tagggttaag cgggtatctg gtcagcagag
    11881 gggtgaaaaa aagggaaatc aacgacatcg aaaccgttga cgaactcgct atcgcttgtg
    11941 gcgcacatca gccttcggtg gtgtttatta atgaggactg tttcattcat acgccttcag
    12001 acagtcaaca aataaagcaa atcattaatc agcatcctga cacgttattt attgttttta
    12061 tggcaattgc taatgtgcat tttgatgaat atttattagt aagaaaaaac ttattgatta
    12121 gctctaaatc gattaaacct gactcgctgg atacccttct tggcgatatt ctgaaaaaag
    12181 agtcgggtat ttcaggaa
//
LOCUS       DAJVBX010000142        12145 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.142, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000142 DAJVBX010000000
VERSION     DAJVBX010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 12145)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12145)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12145
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.142"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(138..1016)
                     /locus_tag="OPV72_003230"
     CDS             complement(138..1016)
                     /locus_tag="OPV72_003230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCR9915451.1"
                     /translation="MTLQHTRRIVKSLFILFIIVVCIYLLPRVAINAFYYPDNKVYGP
                     TPAEAESITFTAKDGTHLHGWFIPTAFGRPENAVATVIHVHGNAGNMSAHWPLVSWLP
                     ERNVNLFMFDYRGFGESEGTPSQEGLLNDTKSAIDYVRHRADVNPERLVLLGQSLGGN
                     NVLAAVGHCVGCANMRYADQAGIRAIVLDSTFSSYSSIANQMIPGSGYLLDDRYSADR
                     NIASVSPIPVLILHGTADHVIPWQDSEKLYALAREPKQKIFIPDGDHIDAFSGRYANL
                     YRDAMINFIQTALSAK"
     gene            complement(1161..1964)
                     /gene="suhB"
                     /locus_tag="OPV72_003231"
     CDS             complement(1161..1964)
                     /gene="suhB"
                     /locus_tag="OPV72_003231"
                     /EC_number="3.1.3.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000553460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol-1-monophosphatase"
                     /protein_id="HCR9915452.1"
                     /translation="MHPMLTIAVRAARKAGNVIAKNYETPDAAEASQKGSNDFVTNVD
                     KAAEAVIIDTIRKSYPQHTIITEESGEHVGTDQDVQWVIDPLDGTTNFIKRLPHFSVS
                     IAVHIKGRTEVAVVYDPMRNELFTATRGQGAQLNGYRLRGSTARDLDGTILATGFPFK
                     AKQYATTYINIIGKLFTECADFRRTGSAALDLAYVAAGRVDGFFEIGLRPWDFAAGEL
                     LVREAGGIVSDFTGGHNYMMTGNIVAGNPRVVKAMLANMRDELSDALKR"
     gene            2083..2814
                     /gene="trmJ"
                     /locus_tag="OPV72_003232"
     CDS             2083..2814
                     /gene="trmJ"
                     /locus_tag="OPV72_003232"
                     /EC_number="2.1.1.200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (cytosine(32)/uridine(32)-2'-O)-methyltransferase TrmJ"
                     /protein_id="HCR9915453.1"
                     /translation="MLQNIRIVLVETSHTGNMGSVARAMKTMGLTNLWLVNPLVKPDS
                     QAIALAAGASDVIGNAQIVDTLDEALAGCSLVVGTSARSRTLPWPMLDPRECGLKSVA
                     EAANTPVALVFGRERVGLTNDELQKCHYHVAIAANPEYSSLNLAMAVQVIAYEVRMAW
                     LATQENGDAADHEETPYPLVDDLERFYGHLEQTLLSTGFIRENHPGQVMNKLRRLFTR
                     ARPESQELNILRGILASIEQQNKGK"
     gene            3056..3550
                     /gene="iscR"
                     /locus_tag="OPV72_003233"
     CDS             3056..3550
                     /gene="iscR"
                     /locus_tag="OPV72_003233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001241352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly transcriptional regulator
                     IscR"
                     /protein_id="HCR9915454.1"
                     /translation="MRLTSKGRYAVTAMLDVALNSEAGPVPLADISERQGISLSYLEQ
                     LFSRLRKNGLVSSVRGPGGGYLLGKDAGSIAVGEVISAVDESVDATRCQGKGGCQGGD
                     KCLTHALWRDLSDRLTGFLNNITLGELVNNQEVLDVSGRQHTHDAPRASGRAQDAIDV
                     KLRA"
     gene            3731..4945
                     /gene="iscS"
                     /locus_tag="OPV72_003234"
     CDS             3731..4945
                     /gene="iscS"
                     /locus_tag="OPV72_003234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017459011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HCR9915455.1"
                     /translation="MKLPIYLDYSATTPVDPRVAEKMMQFLTLDGTFGNPASRSHRFG
                     WQAEEAVDIARNQIAELVGADPREIVFTSGATESDNLAIKGAANFYQKKGKHIITSKT
                     EHKAVLDTCRQLEREGFEVTYLAPQRNGIIDLNELEAAMRDDTILVSIMHVNNEIGVV
                     QDIATIGEMCRARGIIYHVDATQSVGKLPIDLSQLKVDLMSFSGHKIYGPKGIGALYV
                     RRKPRIRIEAQMHGGGHERGMRSGTLPVHQIVGMGEAYRIAKEEMETEMARLRGLRNR
                     LWNGIKDIEEVYLNGDLEQGAPNILNVSFNYVEGESLIMALKDLAVSSGSACTSATLE
                     PSYVLRALGMNDELAHSSIRFSLGRFTTEEEIDYTIDLVRKSIGRLRDLSPLWEMYKQ
                     GVDLNSIEWAHH"
     gene            4973..5359
                     /gene="iscU"
                     /locus_tag="OPV72_003235"
     CDS             4973..5359
                     /gene="iscU"
                     /locus_tag="OPV72_003235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold IscU"
                     /protein_id="HCR9915456.1"
                     /translation="MAYSEKVIDHYENPRNVGSFDNNDDNVGSGMVGAPACGDVMKLQ
                     IKVNDEGIIEDARFKTYGCGSAIASSSLVTEWVKGKSLDEAQAIKNTDIADELELPPV
                     KIHCSILAEDAIKAAIADYKSKREAK"
     gene            5388..5711
                     /gene="iscA"
                     /locus_tag="OPV72_003236"
     CDS             5388..5711
                     /gene="iscA"
                     /locus_tag="OPV72_003236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster assembly protein IscA"
                     /protein_id="HCR9915457.1"
                     /translation="MSITLSDSAAARVNTFLANRGKGFGLRLGVRTSGCSGMAYVLEF
                     VDEPTAEDTVFEDKGVKVVVDGKSLQFLDGTQLDFVKEGLNEGFKFSNPNVKDECGCG
                     ESFHV"
     gene            5908..6423
                     /gene="hscB"
                     /locus_tag="OPV72_003237"
     CDS             5908..6423
                     /gene="hscB"
                     /locus_tag="OPV72_003237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone HscB"
                     /protein_id="HCR9915458.1"
                     /translation="MDYFTLFGLPARYQIDTQALSFRFQDLQRQYHPDKFANGTQAQQ
                     LAAVQQSATINQAWQTLRHPLTRAEYLLSLHGFDLASEQHTVRDTAFLMEQLTLREEL
                     DDIEQSKDDARLESFIKRVQKMFDARLQQMVEQLDNAAWDAAADTVRKLRFLDKLRSS
                     AEQLEEKLLDF"
     gene            6436..8286
                     /gene="hscA"
                     /locus_tag="OPV72_003238"
     CDS             6436..8286
                     /gene="hscA"
                     /locus_tag="OPV72_003238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001559634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S protein assembly chaperone HscA"
                     /protein_id="HCR9915459.1"
                     /translation="MALLQISEPGLSAAPHQRRLAAGIDLGTTNSLVATVRSGQAETL
                     PDHEGRHLLPSVVHYQQQGHTVGYAARDNAAQDTANTISSVKRMMGRSLADIQARYPH
                     LPYRFKASVNGLPMIDTAAGLLNPVRVSADILKALAARASESLSGELDGVVITVPAYF
                     DDAQRQGTKDAARLAGLHVLRLLNEPTAAAIAYGLDSGKEGVIAVYDLGGGTFDISIL
                     RLSRGVFEVLATGGDSALGGDDFDHLLADYIREQAGIADRSDNRVQRELLDAAITAKI
                     ALSDADTVRVNVAGWQGEITREQFNDLISALVKRTLLACRRALKDAGVEPQDVLEVVM
                     VGGSTRVPLVRERVGEFFGRTPLTAIDPDKVIAIGAAIQADILVGNKPDSEMLLLDVI
                     PLSLGLETMGGLVEKVIPRNTTIPVARAQDFTTFKDSQTAMSIHVMQGERELVQDCRS
                     LARFALRGIPPLPAGGAHIRVTFQVDADGLLSVTAMEKSTGVEASIQVKPSYGLTDGE
                     IASMIKDSMSFAEQDVKARMLAEQKVEAARVLESLTGALTADAALLSAAERQCIDDAA
                     AHLSAVAQGDDVDAIEQAIKNVDKQTQEFAARRMDQSVRRALKGHSVDEV"
     gene            8288..8623
                     /gene="fdx"
                     /locus_tag="OPV72_003239"
     CDS             8288..8623
                     /gene="fdx"
                     /locus_tag="OPV72_003239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015683702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISC system 2Fe-2S type ferredoxin"
                     /protein_id="HCR9915460.1"
                     /translation="MPKIVILPHQDLCPDGAVLEAETGETILDVALRNGIEIEHACEK
                     SCACTTCHCIVREGFDSLPESSEEEDDMLDKAWGLEPESRLSCQARVTDDDLVIEIPR
                     YTINHAREH"
     gene            8635..8835
                     /gene="iscX"
                     /locus_tag="OPV72_003240"
     CDS             8635..8835
                     /gene="iscX"
                     /locus_tag="OPV72_003240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004104502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein IscX"
                     /protein_id="HCR9915461.1"
                     /translation="MGLKWTDSREIGEALYDAYPDVDPKTVRFTDLHQWICELDDFDD
                     DPNASNEKILEAILLVWLDEAE"
     gene            8889..10172
                     /gene="pepB"
                     /locus_tag="OPV72_003241"
     CDS             8889..10172
                     /gene="pepB"
                     /locus_tag="OPV72_003241"
                     /EC_number="3.4.11.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase PepB"
                     /protein_id="HCR9915462.1"
                     /translation="MTEAMKITLSTQPADARWGDKATYSINNDGITLHLNGKDDLGLI
                     QRAARKIDGLGIKQVALTGEGWDTERCWAFWAGYKGPKGVRTVMWPDLDDAQRQELDN
                     RLTIIDWVRDTINAPAEELGPEQLAQRAVDLLCSVACDSVTYRITKGEDLREQNYMGL
                     HTVGRGSERPPVLLALDYNPTGDKDAPVYACLVGKGITFDSGGYSIKQSAFMDSMKSD
                     MGGAATVTGALAFAITRGLNKRVKLFLCCADNLISGNAFKLGDIIRYRNGKNVEVMNT
                     DAEGRLVLADGLIDASAQHPRLIIDMATLTGAAKTALGNDYHALFSFDDTLAGRLLTS
                     AAQENEPFWRLPLAEFHRNQLPSNFAELNNTGSATYPAGASTAAGFLSHFVENYREGW
                     LHIDCSATYRKAPVEQWAAGATGLGVRTIANLLTA"
     gene            10282..11058
                     /gene="sseB"
                     /locus_tag="OPV72_003242"
     CDS             10282..11058
                     /gene="sseB"
                     /locus_tag="OPV72_003242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311415.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enhanced serine sensitivity protein SseB"
                     /protein_id="HCR9915463.1"
                     /translation="MSETKNELEILLEKAATEPAHRSAFFRTLLESTVWVPGSAAEGE
                     AIVEDSALDLQHWEKEDGTTVIPFFTSLEALQQAVEDEQAFVVMPARTLFEMTLGETL
                     FLNAKLPTGKEFMPREISLLLAEEGSPLSTQEVLEGGESLILSEVAEPPSQMIDSLTT
                     LFKTIKPVKRAFLCAIKEHADAQPNLLIGIEADGEIEEIIHAAGNVATDTLPGDEPID
                     ICQVRKGAQGISHFITEHIAPFYERRWGGFLRDFKQNRII"
     gene            complement(11627..>12145)
                     /locus_tag="OPV72_003243"
     CDS             complement(11627..>12145)
                     /locus_tag="OPV72_003243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5066 family protein"
                     /protein_id="HCR9915464.1"
                     /translation="SLKALLAYDRDLLSNYNMPVIETLQRFIDNEGVIHSYSPDEEAY
                     YGAGMDSSGIDIEDLMPVWSNDPRLPALIRIDHVGDQAIFIYITERDANGEYPIARME
                     RNEFWLAESSLVEYLYNIISGAKDIGFTEEDLHLPQWKAQQKMNEQRDAALLDLEDYH
                     EAFWAKLDALVD"
BASE COUNT         2879 a         3118 c         3459 g         2689 t
ORIGIN      
        1 ttgttataaa aatcagatga atattactgt tacgctagcg ctaatccgcc gccttcgcta
       61 acgggaaaaa atggttttta ctatcggtat aataaatata ttcttaatca taaaatatgc
      121 atatatacag cgtcgcgcta tttagcggat agcgctgtct gaataaaatt aatcatcgca
      181 tcgcggtaaa ggtttgcata acgtccggaa aaagcatcaa tgtgatcgcc gtcaggaatg
      241 aagatttttt gtttgggctc ccgggcgagg gcatacaatt tctcactgtc ctgccaggga
      301 ataacatggt ctgccgtgcc atgaagaatc aataccggaa tggggctgac gctggcgata
      361 ttgcgatccg cgctatagcg gtcatcaagc aaatagccgc tgcccgggat catctggttg
      421 gcgatggagg aataggatga aaacgttgag tcgaggacaa tcgcacgtat gcccgcctgg
      481 tcggcgtagc gcatatttgc gcagcctacg cagtggccta cggcggccag tacattattg
      541 ccgcccaggc tctgccccag cagtaccagg cgctcggggt taacgtcggc acgatgccgc
      601 acataatcta tcgcgctttt cgtatcgttc agtagcccct cttgtgatgg ggtgccctca
      661 gattcgccaa acccacggta atcaaacata aacaggttta cgttgcgttc tggcagccaa
      721 ctgactaacg gccagtgcgc cgacatattt ccggcgttgc catggacatg aatcaccgtc
      781 gcgacggcgt tttccggcct gccgaaagca gtaggaataa accagccgtg cagatgcgtg
      841 ccatctttgg cggtaaaggt aatggattca gcttcggcag gggttggtcc atagacttta
      901 ttgtccgggt aataaaaggc attgatcgct acgcggggta gcaggtaaat acagactaca
      961 atgataaaca gaataaaaag ggatttgacg atgcgtcggg tatgttgaag ggtcatgttc
     1021 gcttccttgc cgctttatgt ccatagcgga gcagggagcg atcgtacaaa aacatgcagg
     1081 caagtaaagc gatgaggtgg tgtttaggaa aaacgcctga aaaggcacgg cggatgagtg
     1141 gccccatccg ccgaagagac ttagcgcttc agcgcatcgc tcagttcgtc gcgcatattc
     1201 gccagcatgg ctttaacgac gcgcggattc cccgccacga tattaccggt catcatgtag
     1261 ttatgaccgc cggtgaaatc gctgacgata ccgcccgctt cacgaaccag cagttcgccc
     1321 gcggcgaaat cccacggacg aaggccaatt tcaaagaaac catcgacacg acctgcagcc
     1381 acataggcca gatccagcgc ggcggaaccg gtgcggcgga aatcggcgca ttcggtgaac
     1441 agcttgccga taatattaat gtaggtggtc gcgtattgtt tggctttgaa cgggaagccg
     1501 gtagcgagga tagtgccgtc cagatcgcgc gcggtactgc cgcgcagacg gtagccgttc
     1561 agctgcgcgc cctgaccgcg ggtggcggtg aacagttcgt tacgcatcgg atcgtaaacg
     1621 acagccactt cagtacggcc tttaatgtgt acagcaatgg aaacagagaa gtgtggcaga
     1681 cgtttgatga agttggtggt gccatccagc ggatcgataa cccattgaac atcctgatct
     1741 gtgccaacgt gctcaccgct ttcttcggtg ataatagtgt gttgcgggta agatttgcga
     1801 atggtgtcga taattaccgc ttcagcggcc ttatctacgt tggtcacaaa atcgttactg
     1861 cctttttggc tcgcttctgc agcgtccgga gtttcatagt ttttggcaat tacattaccc
     1921 gccttgcgcg ctgcgcgcac ggcgatggtc agcatcggat gcatcggtct ctctcactgg
     1981 atgttaaaga acgggaaaac ggcgcagagt atagcagcga gatcggaatc tgtcttggtt
     2041 ttatggtaag atgtccgaat aatctttagc tgaagaaaga caatgctgca aaacattcga
     2101 attgtgctgg tggaaacctc ccacaccggc aatatgggct ctgtggctcg cgctatgaaa
     2161 accatgggct taactaacct gtggctggta aacccgctgg tgaaaccgga ctcccaggcc
     2221 atcgccctgg cggcaggcgc cagcgatgtg atcggtaatg cgcagatcgt cgatacgctg
     2281 gacgaagcgt tggctggctg tagcctggtg gtcggcacca gcgcccgctc ccgcactctg
     2341 ccgtggccga tgcttgatcc gcgcgagtgc ggcttaaaaa gcgtagcgga agcggcaaat
     2401 acgccggttg cgctggtttt tggtcgtgag cgtgtcgggc tgactaacga tgagttgcaa
     2461 aaatgccatt atcacgtcgc gattgccgct aacccggagt acagctcgtt gaatctggcg
     2521 atggcggtac aggtcatcgc gtatgaagtc cgcatggcct ggctggcgac gcaggaaaac
     2581 ggcgacgcgg cagatcatga agagacaccg tatccgctgg tggacgatct tgaacgtttt
     2641 tacggccatc tggagcagac gttgctctcc actggcttta ttcgcgaaaa ccatccgggg
     2701 caggtgatga ataaattgcg ccgtctgttt acccgcgccc gcccggaaag ccaggagttg
     2761 aatattctgc gtgggattct ggcgtctatt gagcagcaga ataaaggcaa gtaaccgcgt
     2821 taatgccgga tggctcttcg cttatccgac ctacaaatcg tgcggcctgt aggccggata
     2881 agcgaagcgc catccggcac atcaataccg cacggaacgc taaatacctg actaatttac
     2941 tcaagtaaat agttgaccaa tttactcggg aatgtcagac ttgtccctgc tatgcaatac
     3001 ccccatttta caataaaaaa ccccgggcag gggcgagttt gaggttaagt aagacatgag
     3061 actgacatct aaagggcgtt atgccgtgac cgcaatgtta gacgttgcgc tcaactccga
     3121 agcgggcccg gtaccgttgg ctgatatttc tgaacgtcag gggatttccc tttcttatct
     3181 ggaacagcta ttttcccgtt tacgtaaaaa cggtctggtt tccagcgtac gcgggccggg
     3241 cggcggttat ctgctgggta aagatgctgg cagtatcgcg gtcggcgaag tgatcagcgc
     3301 ggttgatgaa tccgttgacg cgacccgttg ccagggcaaa ggcggctgcc agggcggcga
     3361 taaatgcctg acccatgcgc tgtggcgtga tttaagcgat cgtctgaccg gttttctcaa
     3421 caatattact ttaggcgagc tagtgaataa ccaggaagtt ctggatgtgt ctggtcgcca
     3481 gcacacgcat gacgcgccgc gcgccagcgg tcgtgcgcag gacgctatcg acgttaaatt
     3541 acgcgcttaa ttaaaatatt acgccatctc ttctggcggc ctcatgcggt gaatgccgcg
     3601 gtcgtctgaa ggatgaagcg taaaaaagaa ttcagaatca ggccgggacg cggacgtccc
     3661 gtcaacacgg tcgtacatcc agccggttgc ctgattcctt gcattgagtg atgtacggag
     3721 tttaagagca atgaaattac cgatttatct cgactactcc gcaaccacgc cggtggaccc
     3781 gcgtgttgcc gagaaaatga tgcagtttct gaccctggac ggaacctttg ggaacccggc
     3841 gtctcgttca caccgtttcg gctggcaggc tgaagaagcc gtcgatatcg cccgcaacca
     3901 gattgctgaa ctggtcggcg ccgacccgcg tgaaatcgtc tttacctcag gggcgacgga
     3961 gtccgataac ctggcgatca aaggcgctgc caacttttat cagaaaaaag gcaagcacat
     4021 catcaccagc aagaccgagc acaaagcggt gctggacacc tgccgtcagc ttgagcgcga
     4081 agggtttgaa gtgacctacc tggcgccgca gcgcaacggc atcatcgatc tcaacgagct
     4141 cgaagcagcg atgcgtgacg acaccattct ggtttccatc atgcacgtga acaacgaaat
     4201 cggcgtggtg caggatatcg cgaccatcgg cgaaatgtgc cgcgcgcgcg gtatcatcta
     4261 ccacgttgac gccacccaga gcgtgggcaa actgcctatc gacctgagcc aactgaaagt
     4321 ggatctgatg tccttctccg gtcataaaat ttatggtccg aaaggcattg gcgcgctgta
     4381 tgtgcgtcgt aagccgcgta ttcgcattga agcgcagatg catggcggcg ggcacgagcg
     4441 cggtatgcgc tctggtactc tgcctgttca ccagatcgtc ggcatgggcg aagcttaccg
     4501 tatcgcgaaa gaagagatgg agaccgaaat ggcccgtctg cgcggtctgc gtaaccgtct
     4561 gtggaacggc atcaaagata ttgaagaagt ttacctgaac ggcgaccttg agcagggcgc
     4621 gccaaacatt ctcaacgtga gctttaacta cgttgaaggc gagtcgctga tcatggcgct
     4681 gaaagacctg gcggtctctt ccggttccgc ctgcacctcc gccactctgg aaccgtccta
     4741 cgtgctgcgc gcgttgggca tgaatgacga gctggcgcat agctctatcc gtttctcttt
     4801 aggtcgtttt accactgaag aagagatcga ctacaccatt gatctggttc gtaaatccat
     4861 tggccgtctg cgtgaccttt ctccactgtg ggaaatgtac aagcagggtg tggatctgaa
     4921 cagcatcgaa tgggcacatc attaatcggt atcggaatca ggagaattta taatggctta
     4981 cagcgaaaaa gtaatcgatc actatgagaa cccgcgtaac gtagggtcgt ttgacaacaa
     5041 cgacgataac gtgggaagcg gtatggttgg cgcgccggcc tgcggcgacg tcatgaagtt
     5101 gcagattaaa gttaacgatg aaggtatcat tgaagacgcg cgcttcaaga cttacggctg
     5161 cggttccgct atcgcctcca gttctctggt aacggagtgg gtgaaaggga aatccctgga
     5221 cgaagcgcag gcgattaaaa acaccgacat tgcagacgaa ctggagctgc cgccggtgaa
     5281 aattcactgc tctattctgg cggaagacgc gattaaagcc gctattgcgg attacaaaag
     5341 caaacgcgaa gcgaaataaa atagaacgtt aacattgagg ttttgttatg tcgattacac
     5401 ttagcgacag tgcagcagcg cgagttaata ccttcctggc caaccgtggt aaagggtttg
     5461 gtctgcgtct gggcgtgaga acctccggct gctcaggtat ggcttatgta ctggaatttg
     5521 ttgacgagcc gacggcggaa gacaccgtgt ttgaagacaa aggcgttaag gtagtggttg
     5581 acggcaagag cctgcaattt ctggacggta cacagctgga cttcgtaaaa gaaggcctga
     5641 acgaagggtt taaattctcc aacccgaatg tgaaagatga gtgtggttgc ggcgaaagct
     5701 tccacgtgta actgtgttcc gctgttatac cgagtcattc gtgctgcaga aaagcggcaa
     5761 gcgagtgaat ccccaggcgc ttacttaagt aagtgactgg gggaacccgc gcagacaacg
     5821 catctgcggc gcgaagtaag aaggtataac cccaccgtgg tcgcctgcgt gtggggtttg
     5881 ttctgacagg ctatccctga gaatgttatg gattacttca ccctctttgg cttaccagcc
     5941 cgttatcaga ttgacaccca ggcgctgagc tttcgttttc aggatctgca acgccagtat
     6001 caccctgaca aatttgccaa cggcactcag gcgcagcagc ttgccgccgt ccagcaatcc
     6061 gccacgatca accaggcctg gcaaacgctg cgtcaccctt tgacgcgcgc ggagtatctg
     6121 ctttccttac acgggttcga tctggccagc gagcagcata cggtacgcga caccgcgttt
     6181 ctgatggaac aactcacgct tcgcgaagag ctggacgata tcgaacaatc aaaagacgac
     6241 gcgcggctgg aaagcttcat caaacgcgta caaaagatgt ttgatgctcg tcttcagcaa
     6301 atggtggaac agttggacaa cgccgcgtgg gacgcggcgg cggatacggt gcgcaaactg
     6361 cggtttctcg ataaactgcg aagcagcgca gaacaactcg aagaaaagct gctcgatttt
     6421 taactggaat ctaacatggc cttattacaa attagtgagc ctggtctgag cgccgcgccg
     6481 catcagcgtc gtctggcggc gggcatcgac ttaggcacta ccaactctct ggttgcgacg
     6541 gttcgcagcg gccaggcgga aacactgcct gaccacgaag ggcgccacct gttgccttca
     6601 gtggttcact atcagcagca gggccatacg gtcggttacg ctgcgcgtga caatgccgcg
     6661 caggatacgg ccaacactat cagctctgtg aaacgcatga tgggacgctc gctggcggat
     6721 atccaggcgc gctatccgca tctgccttac cggtttaagg caagcgttaa tgggctgccg
     6781 atgattgaca cggcggctgg attgctcaat ccggtacgcg tatctgctga tattctcaaa
     6841 gcgctggccg cgcgggctag cgaatcgctc tccggcgagc tggatggcgt ggtgattacc
     6901 gttcccgcct atttcgatga tgcccaacgt cagggaacga aagacgccgc gcggctggca
     6961 ggcctgcatg tactgcgcct gctcaacgaa ccgacggcgg cggcgattgc ctacggtctg
     7021 gactcaggca aagaaggcgt tatcgctgtt tacgatctcg gcggcggtac cttcgatatc
     7081 tctatcttac gcctgagccg cggggtgttt gaagtgctgg cgacgggcgg tgattctgcg
     7141 ctcggcggcg acgactttga ccatctgctg gcggactata ttcgcgagca ggcgggaatt
     7201 gccgatcgta gcgacaatcg cgttcagcgc gaactgctgg atgccgcgat taccgcgaaa
     7261 atcgccttaa gcgatgccga tactgttcgc gttaacgttg cgggctggca gggggagatc
     7321 actcgcgagc agtttaacga tctcatttcc gcgctggtta agcgcacgct attggcctgc
     7381 cgtcgcgcat tgaaagatgc cggcgttgag ccccaggacg ttctggaagt ggtcatggtc
     7441 ggcggttcga cccgtgtacc gctggtgcgt gagcgggtgg gcgaattttt tggccgcacg
     7501 ccgttaaccg ctatcgaccc ggataaagtg atcgctatcg gcgcagcgat tcaggccgat
     7561 attctggtcg gcaacaagcc ggacagcgaa atgctgctgc tggacgtgat tccactctct
     7621 cttgggctgg aaacgatggg tggcctggtg gaaaaagtca ttccgcgcaa caccactatc
     7681 ccggtggcgc gcgcgcagga tttcaccacc ttcaaagaca gtcagaccgc gatgtctatc
     7741 catgtgatgc agggcgaacg cgaactggtg caggactgcc gctcgctggc gcgctttgcg
     7801 ctgcgcggga ttccgccgct gccggcgggc ggggcgcata ttcgcgtgac cttccaggta
     7861 gacgccgatg gcctgttgag cgtcaccgca atggaaaaat ccaccggcgt cgaggcctcc
     7921 attcaggtca aaccttccta tggcctgacc gatggcgaaa tcgcctcgat gatcaaggat
     7981 tccatgagtt ttgccgagca ggacgtgaaa gcgcgtatgc tggcggagca aaaagtcgaa
     8041 gccgcgcgcg tgctggaaag tttgaccggc gcgctaactg ccgacgccgc gctgttaagc
     8101 gccgcagaac gtcaatgcat tgatgatgcc gccgcacatt taagcgcggt cgcacaaggc
     8161 gatgatgttg acgcaataga acaagccatt aaaaacgtag ataaacaaac ccaggaattt
     8221 gccgctcgcc gcatggacca gtcggttcgt cgcgcgttga aaggccattc cgtagacgag
     8281 gtttaacatg ccgaagattg ttattctgcc tcatcaggat ctttgtccgg atggcgcagt
     8341 tctggaagct gagaccggtg aaaccattct tgacgttgcg ctgcgcaacg gcatcgagat
     8401 tgaacacgcc tgtgagaaat cgtgcgcctg caccacctgt cactgtattg tacgtgaagg
     8461 cttcgactcc ttgccggaaa gttcggaaga agaagacgat atgctggata aagcgtgggg
     8521 gctggagccg gaaagtcgac tgagctgcca ggcccgcgtt accgacgacg atctggttat
     8581 cgaaattcca cgttacacaa tcaaccatgc gcgtgagcat taacagaggg tagtatggga
     8641 ctcaagtgga ccgatagccg cgagatcggc gaagcgttat acgacgcata tcctgatgtc
     8701 gatcctaaaa ccgttcgttt caccgatctg catcagtgga tctgcgaact ggacgatttt
     8761 gacgacgacc ctaacgcatc caatgaaaaa attctggagg cgattctgct agtctggttg
     8821 gatgaagcag agtaagtcaa ataacgggct gccctacgac ggcccgtttg ctaataagga
     8881 aaataacaat gacagaagcc atgaaaatta cgctttccac gcagcctgcc gatgcgcgct
     8941 ggggcgataa agccacttac agtattaata acgacggtat taccttgcat cttaacggta
     9001 aagacgatct ggggttgatc cagcgtgcgg cgcgtaaaat cgacggcctg ggaataaaac
     9061 aggtcgcgct gacaggcgaa ggatgggata ccgagcgttg ttgggcattc tgggcgggtt
     9121 acaaaggacc aaaaggcgtc cgtaccgtaa tgtggccgga tttagacgat gcccaacgtc
     9181 aggagctgga taaccgcctg accattattg actgggtgcg cgacaccatt aatgctccgg
     9241 cggaagagct tgggccggag caactggcgc agcgcgcggt ggatctgctg tgcagcgtcg
     9301 cgtgcgatag cgtcacttac cgtatcacca aaggcgaaga tctgcgcgag cagaactata
     9361 tggggttgca taccgtaggc cgtggttctg agcgtccgcc ggtactgctg gcgctggatt
     9421 acaacccgac gggagacaaa gatgcgccgg tttatgcctg cctggtcggt aaaggtatca
     9481 cctttgactc cggcggttac agtatcaaac aaagcgcttt tatggactca atgaaatccg
     9541 atatgggcgg cgcggcgaca gtaacgggcg cgctggcgtt cgccattacc cgtgggctga
     9601 ataaacgcgt aaaactgttc ctgtgctgcg ctgataatct gatcagcggc aacgcgttta
     9661 aactgggcga tattattcgc taccgtaatg gcaagaatgt cgaagtcatg aataccgatg
     9721 cggaagggcg actggtactg gcggatggcc tgattgacgc cagcgcgcaa cacccgcggc
     9781 taatcattga tatggcgacg ttaaccggcg cggcgaaaac ggcgctgggt aacgactacc
     9841 atgcgctatt cagttttgac gatacgctgg cggggcgctt gctgaccagc gcggcgcaag
     9901 agaatgagcc gttctggcgt ctgccgctgg cggagttcca ccgtaaccaa ctgccgtcta
     9961 actttgcgga actgaacaac accggcagcg cgacgtatcc cgccggggca agcaccgccg
    10021 cgggttttct gtcgcacttt gttgaaaatt accgcgaagg ctggctgcac attgactgtt
    10081 ccgccactta tcgcaaagcg ccggttgagc agtgggctgc cggggcaacc ggtctgggtg
    10141 tgcgcaccat cgcgaatctg ctgaccgcct gaacggtgtt tttgtaggcc gggtaagcga
    10201 agcgccaccc ggcattttgc ctgatggcga cgccgtgcgt cttatcaggc ctacaaccca
    10261 tatacataat ttgtgattcc tatgtccgaa actaaaaatg aattagaaat tttgctggag
    10321 aaagcggcga ctgagcccgc gcatcgttcg gcatttttcc gtaccttact ggagtccacc
    10381 gtctgggtgc cgggcagcgc tgccgaaggc gaggcgattg tggaagacag cgctctggat
    10441 ttgcagcact gggaaaaaga agacggcacg accgtcattc ccttctttac ttctctggag
    10501 gcgctgcagc aggccgtgga agacgaacag gcgtttgtgg tgatgccggc gcgcacgctg
    10561 tttgaaatga cgcttggcga aacgttattc ctcaacgcta aattgccgac cggcaaagag
    10621 tttatgccgc gtgaaatcag cctgcttctc gctgaggaag gcagtccgtt aagtacgcag
    10681 gaagtgctgg aaggcggcga gtcgcttatt ttatccgaag tggccgagcc gccgtcgcag
    10741 atgattgatt ccctcactac gctgtttaaa accatcaaac cggtgaaacg cgcatttctc
    10801 tgcgcgatta aagaacatgc ggacgcccaa cctaatctgc tgattggcat tgaggctgac
    10861 ggcgaaattg aagagatcat tcacgcagcg ggcaatgtgg cgaccgacac gttaccgggt
    10921 gacgaaccga tcgatatttg tcaggtgagg aagggcgcgc agggtatcag ccactttatc
    10981 accgagcata tcgcgccgtt ctacgagcgt cgttggggtg ggttcctgcg cgattttaaa
    11041 cagaaccgca tcatctgaag aaaagaaagc cgcccaacag ggcggcctcc tggcttacct
    11101 gctctggacg ttgagcgtta cgggaacaga attacctggg tagcttctgt ctgcgtgaag
    11161 acacaacgtg ccagaaacaa gaagcacgac acaaaagcat cgtaccttca tgttgcggtc
    11221 cttgcgaaga ccgcatcacg gcagcaccgc tggcgataat gccgtgatag caggcactgt
    11281 ggtgtgcctg cgcttacggc catggaacat cctctcctga agccagtgcc cgtttgcgag
    11341 acggcgaagg gggccgggaa agataatacc tcaaatgctg aatagtttcg tcgtgaatta
    11401 acttgacttt gctctcctta aaagggagta tttacctact gtggtgtgcc tgcgttgcta
    11461 tggcaacaaa gcctgctgga aaggccgcga accggaccag cacaaaaaaa ccgctcaact
    11521 gagcggtttt tttgtggcct gcttaaacag tatttatgta gattcgtttt aaatcagcct
    11581 gaacggtagg ccggataagc gtgagcgcca cccgacagca tgtcgattaa tcgacgagcg
    11641 cgtccagttt tgcccaaaac gcctcatgat aatcctccag gtcaagtaaa gcggcatcgc
    11701 gttgttcatt cattttttgc tgtgccttcc attgcggaag atgtaaatcc tcttcggtaa
    11761 agccaatgtc tttagcgccc gaaataatat tatagagata ttccaccaga gaagactccg
    11821 ccagccaaaa ttcattacgt tccatgcggg caatagggta ttcgccgttg gcatcccgtt
    11881 ctgtgatata gataaaaatg gcctgatcgc cgacatgatc aatacgaatt aatgccggaa
    11941 gacggggatc gttactccag acaggcatca gatcttcaat atcaatacct gagctatcca
    12001 tgccagcgcc gtaatacgcc tcttcatcag gagagtaaga atgtattact ccctcgttat
    12061 caataaatct ttgtaatgtt tcaatcacag gcatattata attgctaagt agatcgcggt
    12121 cgtaggccag tagcgccttc aggct
//
LOCUS       DAJVBX010000143        12142 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.143, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000143 DAJVBX010000000
VERSION     DAJVBX010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 12142)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12142)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12142
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.143"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(42..836)
                     /gene="thyA"
                     /locus_tag="OPV72_003244"
     CDS             complement(42..836)
                     /gene="thyA"
                     /locus_tag="OPV72_003244"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HCR9915465.1"
                     /translation="MKQYLELIQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLLEGFPL
                     VTTKRCHLRSIIHELLWFLQGDTNIAYLHENNVTIWDEWADENGDLGPVYGKQWRAWP
                     TPDGRHIDQIATVLSQLKNDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLS
                     CQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLDVGDFVWTGGDTHLYSNHMEQTHL
                     QLSREPRALPKLVIKRKPDSLFDYRFDDFEIEGYDPHPGIKAPVAI"
     gene            complement(843..1718)
                     /gene="lgt"
                     /locus_tag="OPV72_003245"
     CDS             complement(843..1718)
                     /gene="lgt"
                     /locus_tag="OPV72_003245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HCR9915466.1"
                     /translation="MTSSYLHFPDFDPVIFSIGPVALHWYGLMYLVGFVFAMWLAVRR
                     ANRPGSGWTKNEVENLLYAGFLGVFLGGRIGYVLFYNFPLFLDNPLYLFRVWDGGMSF
                     HGGLIGVILVMIIFARRTKRSFFQVSDFIAPLIPFGLGAGRLGNFINGELWGRVDPDF
                     RFAMLFPGSRAEDIALLPSHPQWQPIFDTYGVLPRHPSQLYELALEGVVLFIILNLFI
                     RKPRPMGAVSGLFLIGYGAFRIIVEFFRQPDAQFTGAWVQYISMGQILSIPMIIAGAI
                     MMVWAYRRRPQQHVS"
     gene            complement(1931..4177)
                     /gene="ptsP"
                     /locus_tag="OPV72_003246"
     CDS             complement(1931..4177)
                     /gene="ptsP"
                     /locus_tag="OPV72_003246"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HCR9915467.1"
                     /translation="MLTRLREIVEKVASAPRLNEALNILVTDICLAMDTEVCSVYLAD
                     HDRRCYYLMATRGLKKPRGRTVALAFDEGIVGLVGRLAEPINLADAQKHPSFKYIPSV
                     KEERFRAFLGVPIIQRRQLLGVLVVQQRELRQYDESEESFLVTLATQMAAILSQSQVT
                     ALFGQYRQTRIRALPAAPGVAIATGWQDATMPLMEQVYEASTLDTSLERERLTGALEE
                     AANEFRRYSKRFAAGAQKETAAIFDLYSHLLSDARLRRELFAEVDKGAVAEWAVKKII
                     EKFAEQFAALTDNYLKERAGDLRTLGQRLLFHLDDSVQGPNAWPERFILVADELSATT
                     LAELPQDRLAGVVVRDGAANSHAAIMVRALGIPTVMGADIQPSVLHRRTLVVDGYRGE
                     LLVDPEPVLIQEYQRLISEEIELSRLAEDDVNLPAQLKSGERIKVMLNAGLSPEHEEK
                     LGSRIDGIGLYRTEIPFMLQSGFPSEEEQVAQYQGMLQMFNDKPVTLRTLDVGADKQL
                     PYMPISEENPCLGWRGIRITLDQPEIFLIQVRAMLRANAATGNLSILLPMVTSIDEVD
                     EARRLIERAGREVEEMIGYAIPKPRIGIMLEVPSMVFMLPHLANRIDFISVGTNDLTQ
                     YILAVDRNNTRVASIYDSLHPAMLRALSMIAQEAEKHGLDLRLCGEMAGDPMCVAILI
                     GLGYRHLSMNGRSVARVKYLLRHIDFEDAQTLARRSLEAQMATEVRHQVAAFMERRGM
                     GGLIRGGL"
     gene            complement(4190..4720)
                     /gene="rppH"
                     /locus_tag="OPV72_003247"
     CDS             complement(4190..4720)
                     /gene="rppH"
                     /locus_tag="OPV72_003247"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001655775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA pyrophosphohydrolase"
                     /protein_id="HCR9915468.1"
                     /translation="MIDDDGYRPNVGIVICNRQGQVMWARRFGQHSWQFPQGGINPGE
                     SAEQAMYRELFEEVGLSRKDVRILASTRNWLRYKLPKRLVRWDTKPVCIGQKQKWFLL
                     QLMSADAEINMQTSSTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFASVVMALQD
                     NPPKLQSAPAYRRKRG"
     gene            5403..6098
                     /gene="mutH"
                     /locus_tag="OPV72_003248"
     CDS             5403..6098
                     /gene="mutH"
                     /locus_tag="OPV72_003248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutH"
                     /protein_id="HCR9915469.1"
                     /translation="MSALCPLLTPPASEALLLAQARQLSGYTLGELAVMAGITTPKDL
                     KRDKGWIGVLLEIWLGASAGSKPEQDFAALGVELKTIPVDSLGRPLETTFVCVAPLTG
                     NSGVTWETSHVRHKLKRVLWVPVEGDRSIPLAERRVGSPLLWSPSEEEDRQLRLDWEE
                     LMDMIVLGQVERITARHGEVLQLRPKAANARALTEAIGARGEPILTLPRGFYLKKNFT
                     QALLARHFLLQNP"
     gene            6280..6993
                     /locus_tag="OPV72_003249"
     CDS             6280..6993
                     /locus_tag="OPV72_003249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family protein"
                     /protein_id="HCR9915470.1"
                     /translation="MLFAWITDPNAWLALGTLTLLEIVLGIDNIIFLSLVVAKLPTAQ
                     RNHARRLGLAAAMVMRLALLASIAWVTRLTNPLFELFGEAISARDLILLLGGLFLIWK
                     ASKEIHESIEGEEEGLKTRVSSFLGAIVQIMLLDIIFSLDSVITAVGLSDHLFIMMAA
                     VVIAVGVMMFAARPIGEFVDRHPSVKMLALSFLILVGFTLILESFDVHVPKGYIYFAM
                     FFSIAVESLNLLRNKKNPL"
     gene            7164..7382
                     /locus_tag="OPV72_003250"
     CDS             7164..7382
                     /locus_tag="OPV72_003250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgdI/YgdR family lipoprotein"
                     /protein_id="HCR9915471.1"
                     /translation="MKKWAVVISAVGLAFAVSGCSSDYVMATKDGRMILTDGKPQVDD
                     DTGLVSYTDTQGNEMQINRDEVSQIIER"
     gene            7573..8613
                     /locus_tag="OPV72_003251"
     CDS             7573..8613
                     /locus_tag="OPV72_003251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP(H)-dependent aldo-keto reductase"
                     /protein_id="HCR9915472.1"
                     /translation="MHYHRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYTIANGI
                     NLIDAAEMYPVPPRPETQGLTESYIGNWLAKRGNREKLIIASKVSGPARNNDQGIRPH
                     QALDRKNIREALHDSLTRLQTDYLDLYQVHWPQRPTNCFGKLGYNWADSMPVVSLLET
                     LDALSEFQRAGKIRYIGVSNETAFGVMRYLHLAEKHDLPRIVTIQNPYSLLNRSYEVG
                     LAEVSQYEGVELLAYSCLAFGTLTGKYLNGAKPAGARNTLFSRFTRYSGEQAQKAVAA
                     YVDIAKRHNLDPAQMALAFVRRQPFVASTLLGATTMAQLKTNVESLHLTLSEEVLAEI
                     EAVHQVYTYPAP"
     gene            complement(8700..9902)
                     /gene="lplT"
                     /locus_tag="OPV72_003252"
     CDS             complement(8700..9902)
                     /gene="lplT"
                     /locus_tag="OPV72_003252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid transporter LplT"
                     /protein_id="HCR9915473.1"
                     /translation="MSESVRTNTSIWSKGMLSVIVAQFLSAFGDNALLFATLALLKAQ
                     FYPDWSQPVLQMVFVGAYILFAPFVGQIADSFAKGRVMMVANGLKLAGAAGICLGVNP
                     FVGYTLVGIGAAAYSPAKYGILGELTTGDKLVKANGLMEASTIAAILLGSVAGGVLAD
                     WHVIAALVACALAYAGAVAANLFIPKLVAARPGQSWRLSAMTRSFFCACVVLWRNGET
                     RFSLVGTGLFWGAGVTLRFLLVLWVPVALGITDNATPTYLNAMVAVGIVVGAGAAAKL
                     VTLETVSRCMPAGILIGVVVAIFSLQHALLPAYALLLLIGMLGGFFVVPLNALLQERG
                     KKSVGAGNAIAVQNLGENSAMLLMLGLYSLAVLVGVPAVAIGIGFGVLFALAIAALWI
                     WQRRQASY"
     gene            complement(9895..12054)
                     /gene="aas"
                     /locus_tag="OPV72_003253"
     CDS             complement(9895..12054)
                     /gene="aas"
                     /locus_tag="OPV72_003253"
                     /EC_number="2.3.1.40"
                     /EC_number="6.2.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acyl-ACP--phospholipid
                     O-acyltransferase/long-chain-fatty-acid--ACP ligase"
                     /protein_id="HCR9915474.1"
                     /translation="MLFGFFRNLFRVLYRVRVTGDVRALQGNRVLIAPNHVSFIDGML
                     LALFLPVRPVFAVYTSISQQWYMRWLTPLIDFVPLDPTKPMSIKHLVRLVEQGRPVVI
                     FPEGRISVTGSLMKIYDGAGFVAAKSGATVIPLRIDGAELTPFSRLKGLVKRRLFPRI
                     QLHILPPTQIPMPEAPRARDRRKIAGEMLHQIMMEARMAVRPRETLYESLLAAQYRYG
                     AGKNCIEDINFTPDTYRKLLTKTLFVGRILEKYSVEGEKIGLMLPNAAISAAVIFGAV
                     SRRRIPAMMNYTAGVKGLTSAITAAEIKTIFTSRQFLDKGKLWHLPEQLTQVRWVYLE
                     DLKADVTPADKLWIFAHLLAPRLAQVKQQPEDAAIILFTSGSEGHPKGVVHSHKSILA
                     NVEQIKTIADFTANDRFMSALPLFHSFGLTVGLFTPLLTGAEVFLYPSPLHYRIVPEL
                     VYDRNCTVLFGTSTFLGNYARFANPYDFYRLRYVVAGAEKLQESTKQLWQDKFGLRIL
                     EGYGVTECAPVVSINVPMAAKPGTVGRILPGMDARLLAVPGIENGGRLQLKGPNIMNG
                     YLRVEKPGVLEVPSAENARGETERGWYDTGDIVRFDENGFVQIQGRAKRFAKIAGEMV
                     SLEMVEQLALGVSAEKMHATAIKSDASKGEALVLFTTDSELTREKLQHYAREHGIPEL
                     AVPRDIRYLKQLPLLGSGKPDFVTLKSWVDAPEQHHE"
BASE COUNT         2953 a         3426 c         3092 g         2671 t
ORIGIN      
        1 ccgacgcgcg atggcgtcgg ttatggcagg atcgtcagcg cttagatagc gaccggcgct
       61 ttaataccgg ggtgcggatc atagccttca atttcgaaat catcgaaccg gtagtcaaaa
      121 agcgaatcgg gtttacgctt aatgaccaat ttcggcagcg cgcgcggttc acggcttaat
      181 tgcaggtgcg tctgctccat atggttgctg tacaggtgcg tgtcgccgcc ggtccagaca
      241 aaatcgccga cgtccaggtc gcactgttgc gccatcatat gcaccagtaa cgcgtagctg
      301 gcaatgttga acggcagacc gaggaacaca tcgcaggagc gctgataaag ctgacaggag
      361 agttttccat ctgcgacata aaactggaaa aaggcgtgac acggcgccag cgccatctta
      421 tccagctcgc cgacgttcca cgcagaaacg ataatacgac gagagtccgg gtcgttttta
      481 agctggctca agaccgtggc gatctgatcg atatggcggc catccggtgt tggccatgca
      541 cgccactgct taccataaac cgggcctaaa tcgccgttct catcggccca ttcgtcccag
      601 atggtgacat tattttcgtg taggtaagcg atgttggtat cgccctgcaa aaaccatagc
      661 agttcgtgaa taattgaacg taaatggcag cgtttcgtcg tcaccagagg aaagccttcc
      721 agcaggttaa aacgcatctg atggccaaaa atggaaagcg tgccggtgcc ggtacggtcg
      781 tttttctgtg tgccttcatc cagcactttt tgtatcagtt ctaaatactg tttcatggtt
      841 cctcaggaaa cgtgttgctg cgggcggcgg cgatatgccc aaaccatcat gatcgcgcca
      901 gcgataatca tcgggataga gagaatctgc cccatgctga tgtactgtac ccacgcgccg
      961 gtaaattgcg cgtccggctg gcggaagaat tcaacaatga tacgaaacgc gccatagcca
     1021 atcaggaata atccggagac tgcgcccatc ggacgcggtt tgcgaataaa gagattaagg
     1081 atgataaaca gcaccacgcc ttctaatgcc agctcataca actgggaagg gtggcgtggc
     1141 aatacgccgt aggtatcaaa aataggctgc cattgcggat gtgacggcag cagcgcaata
     1201 tcttccgcgc gtgagccagg aaagagcatg gcaaaccgga agtcaggatc gacgcgcccc
     1261 cacaattcac cgttgataaa gttgcccaga cgcccggcgc ccaggccgaa cggaattaac
     1321 ggcgcaataa aatcagacac ctgaaagaac gagcgcttcg tgcgcctggc gaagataatc
     1381 atcaccagta tcacgccgat aagcccgccg tggaaggaca tgccgccgtc ccagacgcgg
     1441 aataaataga gcgggttatc cagaaacaga gggaagttat aaaacaggac atagccaata
     1501 cgtcccccca ggaagacccc caggaaacct gcatagagta aattttcaac ttcgtttttg
     1561 gtccaaccgc ttcccggacg gttagcgcga cgcaccgcca accacatcgc gaaaacgaac
     1621 cccaccagat acatcaagcc ataccagtga agcgcgacgg gcccaattga gaaaatgacc
     1681 ggatcaaagt ccggaaaatg cagatagcta ctggtcatct gtcaccacaa tttcttgtta
     1741 tttcgctgaa gagatagcga ttgataagcg cgcctgcgcg ttgcagacgc tccaaaggtg
     1801 cgaataatag cacaagggtt aaaagcgaga tgccgattac cgttaaaaga tatgtatacg
     1861 cattgtcttt catcttgcag gcgtgttgtc tgcgccgtga atccacagtc actttttccc
     1921 gctccagtcg ttacaaccct ccgcgaatca atccccccat cccgcggcgc tccataaacg
     1981 ccgccacctg atgacgcact tcggtcgcca tctgcgcctc aaggctgcgt ctggcaaggg
     2041 tttgcgcgtc ttcaaaatcg atatgccgca gcagatattt cacacgcgct accgaacggc
     2101 cattcatcga aagatggcga tatcccagac cgataagaat cgccacgcac atcggatcgc
     2161 ccgccatctc gccgcacaag cgaagatcga gaccatgttt ttcggcttcc tgcgcgatca
     2221 tggacagtgc gcgcagcata gccggatgca aactgtcata aatactggcc acgcgggtat
     2281 tgttgcgatc taccgccagg atatattgcg ttaaatcgtt ggtgccgacc gagataaagt
     2341 cgatccggtt agccagatgc ggcagcataa ataccattga tggtacttcc agcataatgc
     2401 cgatacgcgg tttcgggatc gcatagccga tcatctcctc gacctcgcgc ccggcgcgtt
     2461 cgatcagacg ccgcgcttca tcgacttcat caatactggt gaccatcggc aacaaaatgc
     2521 tgaggttgcc agtcgccgca ttggcacgca gcatcgcgcg gacctggatc aaaaagatct
     2581 ccggctgatc cagcgtaatg cggatcccgc gccagcccag acacgggttc tcctcgctga
     2641 tcggcatata gggcagttgc ttatccgctc ccacatccag ggtccgcagc gtcaccggtt
     2701 tatcgttaaa catttgcagc atcccttgat actgcgccac ctgctcttct tccgagggaa
     2761 acccgctttg cagcatgaag ggaatttcag tacggtacag gccgataccg tcgatccgac
     2821 tgcctaactt ttcctcatgc tcggggctga gcccggcatt cagcatcact ttgatacgct
     2881 cgccgctttt cagttgggcg ggaagattga cgtcgtcctc cgccagacga ctgagttcta
     2941 tctcttcact aatgagccgc tgatattcct gaataagcac gggttcagga tcgaccagta
     3001 attcaccgcg atagccatcc accaccaacg tacggcgatg tagcaccgaa ggctggatat
     3061 ccgcgcccat gacggtgggg ataccgagcg cgcgcaccat aatcgccgca tgcgagtttg
     3121 ccgcgccgtc gcgcaccaca acgcccgcca gcctgtcctg cggcagctcc gccagggtgg
     3181 tcgccgacag ctcatccgcg accagaataa aacgttccgg ccaggcgttt ggcccctgaa
     3241 ctgaatcatc aagatggaat aacagccgct gccccagcgt gcgtaagtct cccgcacgtt
     3301 ctttgaggta gttatcggtt agcgccgcaa attgctcggc aaatttttcg atgatttttt
     3361 taacggccca ctccgcaaca gcgcctttgt cgacctcggc gaagagttcg cgacgcagtc
     3421 tggcgtctga aagcaggtgt gagtacagat cgaaaatggc tgccgtctct ttttgtgcgc
     3481 cggcggcaaa gcgtttgctg tatcgtcgga attcgttcgc cgcctcttcc agcgcgccgg
     3541 tcaatcgttc gcgttcaaga gaggtatcca gcgtagacgc ttcgtaaacc tgttccatca
     3601 gcggcatggt cgcgtcttgc cagcccgttg cgatagccac gcccggcgcc gcaggaagcg
     3661 cgcgaattcg cgtctgccgg tattgcccga atagcgctgt gacctgcgac tgtgacagga
     3721 tagccgccat ctgcgtagcg agcgtgacga ggaaagactc ttcgctttca tcgtactggc
     3781 gcaattcgcg ctgctgcacg accagcacgc cgagaagttg gcgacgctga atgatcggca
     3841 caccgagaaa cgcgcgaaaa cgctcctctt ttaccgaagg aatgtattta aagctgggat
     3901 gtttttgcgc atcggcaagg ttaatgggtt ccgccagcct gcccaccaga ccgacgatcc
     3961 cctcatcaaa cgcaagcgca acggttcgac cacgcggttt tttcaacccc cgcgtcgcca
     4021 tcaggtaata acagcgtcgg tcatgatcgg ccaggtaaac cgagcaaacc tctgtatcca
     4081 tcgcaagaca gatatccgtg accagaatat tcagcgcctc gttcagacgc ggcgcactgg
     4141 ccactttttc gactatttcg cgcaggcgag tgagcataat ttgcgtggct taacctcttt
     4201 tacgtcgata agcaggcgcg ctttgtagct tagggggatt atcctgaagc gccatgacaa
     4261 cacttgcaaa ctctttcatt accctgcggt agacatcgcg tttaaatgac accacttgtc
     4321 gaaccggata ccagtaactt acccagcgcc agccgtcaaa ctccggcgta ctgctggttt
     4381 gcatattgat ttcggcgtcg gcgctcatta actgcaaaag aaaccacttt tgtttctggc
     4441 cgatacatac cggctttgtg tcccaacgca ccaaacgttt tggtaacttg taacgcaacc
     4501 agttgcgagt agaagcaagg atccgcacat ctttacggct taacccaact tcttcaaaca
     4561 gttcccggta catcgcctgt tctgccgact cccctggatt tatcccgccc tgcgggaact
     4621 gccaggagtg ctgaccaaat cgccgggccc acatcacctg cccctgacga ttacaaatta
     4681 cgatacctac atttgggcgg tagccatcgt catcaatcac cggactacct caacataaac
     4741 cttatatatg aacgattgtt tcatactcca gtgaggcggt aaaccactct gtaatagtga
     4801 cacagcctaa taacaattga ataactcaca gtaaatagcc gagttataaa cagatgatga
     4861 cgcccttgcg ccattttatt caccttttct gtggatatag ttgtgaagaa gtatggaatt
     4921 accacgggaa aacccagaac agtctgaatt cctcatactg aaaacagtaa aaatagtgcc
     4981 ttatattcat tgtgttatag acaaatctta catgccacct tcataaagcg tgaccagcat
     5041 cacatctaag atccttatgc tgatgaaaga tcaaccagcg tcggttttat ccacagattg
     5101 tgccaataac ttacgcacta tttgtctgaa ttttcgattt tcgtcgcacg tcaaggctgt
     5161 aaatggaaac agtagtggtg gttttacaca gttatcccaa ctttctgtgg ataacatagt
     5221 gtaagatcct gtttattgtt agtgaccaga attggaaaac ccgcttcagc gttgcgcaac
     5281 acgaagaaac aacacaaaaa aggcaataaa aatcagtcta ttgaatataa gacacagaaa
     5341 aagataaact ctgcccatac ggtataaaaa cactgctcat tttttgacct aaggtaattg
     5401 tcatgtccgc tctttgtccg ctactgactc cgcctgcttc ggaagcattg ctgttagccc
     5461 aggcgcggca gctttccggc tatacgttag gcgagctggc ggtgatggcc ggcattacca
     5521 cgcctaaaga tttgaagcga gacaaaggct ggatcggcgt cttgctggag atctggctcg
     5581 gcgccagcgc cgggagcaag ccggagcagg atttcgccgc gttaggcgta gaactgaaaa
     5641 ctatcccggt ggatagtctg ggtcgtcctc tggaaacaac ctttgtttgc gtggcgccgt
     5701 taaccggtaa cagcggcgtg acctgggaga caagtcacgt acggcataaa ttgaagcgcg
     5761 tgctatgggt gccggtcgaa ggcgatcgca gcataccgtt agccgaacgc cgcgtaggtt
     5821 cgccgctact ctggagtccg agtgaagaag aggacaggca gctacgcctc gactgggaag
     5881 agctgatgga catgatagtg ctgggccagg tggaacgcat taccgcccgc catggcgaag
     5941 tcttgcaact gcgacccaaa gccgccaatg ccagggcgct caccgaggct atcggcgcgc
     6001 gcggggaacc tattttgacg ctaccgcgtg gattttatct gaaaaaaaat tttacgcagg
     6061 cgctgctggc tcgccatttt ttattgcaga atccgtaacg tccattacac gcaaatgcgc
     6121 ctccgctatg gctacgcgtc gggccgacgc cggataaacg taagcgtatt gtcgccgcta
     6181 ttttacaccg ttcctggttg cgcaaattca gcctgggctt tcgcccgtca ctcgacgggc
     6241 ctataattac cgcttctttt tttggcagga ctttgttcga tgttatttgc atggataacc
     6301 gatcctaatg cctggctggc gctcggtacg ctgacgctgc tggagattgt acttgggatc
     6361 gacaacatta tttttctttc tctggtggta gcaaaacttc ctacggcgca acggaaccac
     6421 gcacggcggc ttgggttggc ggcggcgatg gttatgcgcc tggcgctgct ggcgtcaatc
     6481 gcctgggtca ctcggctgac taatccgctg tttgagcttt tcggcgaagc gatttccgcc
     6541 cgcgatctca ttctgttact gggtgggtta tttttaatct ggaaagccag caaggagatc
     6601 catgagtcca tcgaaggcga agaagaaggg ttaaaaaccc gggtttcttc tttcctgggc
     6661 gcaatagtgc agattatgct gctggatatt attttcagcc ttgattcagt tatcacagcg
     6721 gttggcctct ccgatcatct gtttattatg atggcggcag tcgttattgc cgtgggtgtc
     6781 atgatgtttg cggcacggcc catcggcgag tttgtcgatc gtcatccgtc ggtaaaaatg
     6841 ctggcgctct cctttctgat cctggttggc tttaccctga ttctggaaag tttcgacgtt
     6901 cacgttccga aagggtatat ctatttcgcc atgttcttct ctatcgcagt agagagcctg
     6961 aacctgttgc gtaataaaaa gaatccgctg taatcctgtc tcgctccccc gccgggggag
     7021 cgaatactca ctttatttcc tttcttctca cagattaaga ttttgctgct tccgacatgc
     7081 agagctgcgc gttattacta gactattatc agacatatga ttaacagact attatcagat
     7141 gcaggctacg tgaggaaaaa cggatgaaaa agtgggcagt tgtaatttcc gcagtagggt
     7201 tggcttttgc ggtatccgga tgcagcagcg attatgtaat ggcgacgaaa gatggtcgta
     7261 tgatcctgac cgatggaaaa ccgcaagttg acgatgatac cggtctggtc agctataccg
     7321 atacacaggg aaacgagatg caaatcaacc gtgacgaagt gtctcaaatc atcgaacgtt
     7381 aagcggtggc ctgtgatcga ggtcagcgtt ctgcaagcct tcaggctgcg tcccgtaacg
     7441 gtgcgtggcg accacgcccg gtaacaatta cgccgtgcag cctgcaattt tactttccct
     7501 tttgccttcc ctctgccatt tttattgtcc tttgtcggga atttctgact tcataataaa
     7561 aaggaaacgg ctatgcacta tcaccgtata ccccacagct cgctcgaagt aagtacgcta
     7621 gggctgggca caatgacatt tggtgaacaa aacagcgaag ccgacgctca cgcacagctc
     7681 gactatacca tcgcaaatgg cattaacctt atcgacgccg ccgagatgta tccggtaccg
     7741 ccgcgcccgg aaacacaagg gctgacggag tcctatatcg gtaactggct cgccaaacgc
     7801 ggcaaccgtg aaaaactgat catcgccagc aaagttagcg gaccggcacg taataatgat
     7861 caaggcatcc ggcctcatca ggcgctggat cgtaaaaata ttcgcgaagc gctacacgac
     7921 agtttgaccc ggttgcagac cgactatctg gatttgtatc aggtgcactg gccgcagcgc
     7981 cccactaact gcttcggtaa actcggctat aactgggcgg actccatgcc agtagtaagt
     8041 ctgctggaga cgttagacgc gctaagtgag tttcagcgag cgggtaagat tcgttatatt
     8101 ggcgtttcaa atgagacagc gtttggcgtt atgcgctatc tgcatctggc ggaaaaacat
     8161 gacctgccgc gtattgtcac tatccagaac ccctatagcc tgttaaaccg cagctacgag
     8221 gtcggactgg cggaagtcag ccagtatgaa ggtgttgaat tgctcgccta ttcctgtctg
     8281 gcgtttggca cattaaccgg taaatacctg aacggggcca aacccgcagg cgcgcggaat
     8341 accttgttca gccgcttcac acgttacagc ggcgaacagg cacaaaaagc cgttgccgcc
     8401 tacgtcgata tcgcgaagcg tcacaatctt gatccggcgc agatggcgct ggcctttgtt
     8461 cgccgccagc cgtttgtcgc cagtacgtta ctgggcgcaa ccacgatggc gcagctcaag
     8521 acgaatgtgg aaagtctgca tctgacgtta agcgaagagg tcctggcgga gatagaggcg
     8581 gtgcatcagg tttataccta cccggcgccg tgatggtcag tgcccggtgg cgctacgctt
     8641 ccgggcttac agagacaatg taagccggat aacgcgcact cgccgcccgg catattcact
     8701 cagtatgatg cctgccggcg ctgccagatc cacagcgccg cgatcgccag cgcgaacagc
     8761 acgccaaagc cgatacctat cgccactgcc ggaacgccaa ccagcaccgc cagcgagtac
     8821 agtcccagca ttaatagcat ggcgctattc tcgcccagat tttgtacggc aatggcattc
     8881 ccggcaccaa cgctcttctt accgcgctcc tggagcaaag cgttgagcgg caccacaaaa
     8941 aagccgccca gcatacctat caacaacaac aaggcataag caggcagcaa tgcgtgctgt
     9001 aatgagaaga tcgcaaccac aacgccaatc aaaatcccag cgggcataca gcgcgatacg
     9061 gtctccagcg tcaccagttt tgccgccgca cccgcgccga ccacaatgcc taccgccacc
     9121 atggcgttca ggtaagtcgg cgtggcgtta tccgtaatgc ccagcgccac cggcacccac
     9181 agcaccagca gaaaacgcag cgtcacgcct gcgccccaga atagcccggt ccccaccagc
     9241 gaaaaacgcg tttcaccgtt acgccaaagg acaacgcaag cgcagaagaa gctacgcgtc
     9301 atcgccgaca accgccagga ttgtcctgga cgcgccgcca caagcttcgg gataaacagg
     9361 ttcgccgcca ctgcgccagc gtaggccaac gcgcaggcaa ccagcgcggc gatgacatgc
     9421 cagtcggcca atacgccgcc cgcgacggaa ccgagcaaaa tcgccgcaat cgtagaggct
     9481 tccatcaggc cattggcttt caccagctta tcgcccgtcg tcagttcgcc cagaataccg
     9541 tatttcgccg gagaataagc cgccgcgcca atcccgacca acgtataacc gacaaaagga
     9601 tttacgccga ggcagatacc tgccgctccc gccagtttaa gaccattggc gaccatcatc
     9661 acccggcctt tggcaaagct gtccgctatc tggccgacaa acggcgcaaa aagaatgtaa
     9721 gcgcccacaa acaccatttg caaaacaggc tggctccagt ccgggtaaaa ctgagctttc
     9781 agcagtgcca gcgtcgcgaa cagcagcgca ttatcgccaa aagccgagag aaactgcgcg
     9841 acaattaccg acagcatccc tttcgaccag atggaggtgt tagtacgtac tgactcactc
     9901 atgatgttgt tccggcgcat ccacccaact tttcagcgtc acaaaatcgg gtttcccgct
     9961 gccaagcaag ggaagctgtt tcagataacg gatatcacgc gggacggcaa gttccggaat
    10021 accgtgttca cgggcatagt gctgtaactt ttctcgggtg agttcgctgt cagtcgtaaa
    10081 cagtaccagc gcttcacctt tgctggcatc gcttttaatg gcggtagcgt gcattttctc
    10141 cgccgaaacg ccaagcgcca gttgctcgac catctccagc gagaccattt cgccagcaat
    10201 tttcgcaaag cgtttcgcgc gcccctgaat ctgcacaaaa ccattttcat cgaagcgtac
    10261 aatatcgccc gtgtcgtacc acccgcgctc ggtttcgcct ctggcgtttt ccgccgacgg
    10321 cacctccagc acgcccggtt tttccacgcg cagatagcca ttcatgatat tcggcccttt
    10381 cagctgtagc cgaccgccgt tttcaatacc gggcaccgcc agcagacgcg cgtccatgcc
    10441 aggcagaatg cggccaacag tgccaggctt agccgccatc ggcacgttaa tcgagactac
    10501 tggcgcgcat tccgttaccc cgtagccctc aagaatgcgc agaccgaatt tatcctgcca
    10561 cagttgtttg gtgctctcct gaagtttttc cgcaccggcc accacatagc gcaggcgata
    10621 aaaatcatac ggattggcaa agcgcgcata gttgccgagg aaggttgatg taccaaacag
    10681 cacggtacag ttacggtcat agaccagttc cggcacaatg cggtagtgca gcggacttgg
    10741 ataaagaaac acttccgcgc cggtcaacaa cggcgtaaac aggcccaccg tcaaaccgaa
    10801 cgagtgaaag agcggcagcg ccgacataaa acgatcattg gcggtgaaat ccgcaatcgt
    10861 ttttatctgc tcgacgttcg ccagaatact tttatggctg tgcaccaccc ctttcgggtg
    10921 cccttccgag ccggaggtaa aaagaataat cgccgcgtct tccggctgct gttttacctg
    10981 cgccagtcgc ggcgccagga ggtgggcaaa aatccacagc ttgtcggcgg gtgtgacgtc
    11041 cgcttttaaa tcttccaggt aaacccagcg aacctgcgtt agctgctccg gcaggtgcca
    11101 caatttacct ttatcgagga actggcggga ggtaaaaatc gttttaattt ccgccgcggt
    11161 aatcgcgctg gtcagccctt ttacccccgc cgtgtagttc atcatggccg gaatgcggcg
    11221 acgagaaacc gcgccgaaaa tcaccgccgc gctgatggcg gcattcggca gcattaaacc
    11281 gattttctcg ccctcaacgc tgtacttttc cagaatccgg ccaacaaaaa gcgtcttggt
    11341 cagtaactta cgatacgtat ccggcgtaaa gttaatgtcc tcaatacagt ttttacccgc
    11401 gccgtaacga tattgcgccg ccagcaacga ttcgtataac gtctcgcgcg ggcgcactgc
    11461 catacgcgct tccatcatga tctggtgcag catctcaccc gctatcttac gtctgtcgcg
    11521 cgcgcgcggc gcttccggca tcggtatttg cgtcggcggt aaaatatgaa gctgaatgcg
    11581 ggggaataag cgccgtttaa ccagaccttt caggcgactg aaaggggtaa gctccgcgcc
    11641 gtcaatgcgg agcggaatga cggttgcgcc cgattttgcc gccacaaagc ctgcgccgtc
    11701 ataaattttc atcagcgagc cggtcacgga aatccgccct tccgggaaaa tcaccactgg
    11761 acgcccctgc tccaccagac gcaccaggtg tttaatggac atgggtttag tgggatcgag
    11821 cggtacaaaa tcgatcagcg gcgttaacca gcgcatatac cattgctggc tgatggaggt
    11881 atataccgca aagacaggcc gtaccggcaa aaacagcgcc agtagcatac catcgataaa
    11941 tgaaacgtga ttgggggcaa ttaagacccg gttcccctgt agcgcccgga catcgccagt
    12001 gacgcgcaca cgataaagca cgcgaaacag gttacggaaa aatccaaaca gcatttcaac
    12061 tccctttggc cgacaattcg ctaaaacatg aattgtggca gattacacga gttgcgtaac
    12121 aggagcgata gcaaaatagg tt
//
LOCUS       DAJVBX010000144        12047 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.144, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000144 DAJVBX010000000
VERSION     DAJVBX010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 12047)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12047)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12047
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.144"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..142)
                     /locus_tag="OPV72_003254"
     CDS             complement(<1..142)
                     /locus_tag="OPV72_003254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_447236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915475.1"
                     /translation="MATDYIILLKKEVMEARAFISQALQILNDLSEIMTTMASCLKLR
                     ISL"
     gene            complement(451..2472)
                     /gene="uvrB"
                     /locus_tag="OPV72_003255"
     CDS             complement(451..2472)
                     /gene="uvrB"
                     /locus_tag="OPV72_003255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HCR9915476.1"
                     /translation="MSKPFKLNSAFKPSGDQPDAIRRLEEGLEDGLAHQTLLGVTGSG
                     KTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEFFPENAVEYFVSYYDYYQPEAYV
                     PSSDTFIEKDASVNEHIEQMRLSATKALLERRDVVVVASVSAIYGLGDPDLYLKMMLH
                     LTVGMLIDQRAILRRLAELQYTRNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFD
                     EEVERLSLFDPLTGQVESTVPRYTIYPKTHYVTPRERILQAMEEIKDELADRRKVLLA
                     NNKLLEEQRLSQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGEPPPTLFDYLPADGL
                     LVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYV
                     SATPGNYELEKSGDEVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVL
                     VTTLTKRMAEDLTEYLEEHGERVRYLHSDIDTVERMEIIRDLRLGEFDVLVGINLLRE
                     GLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPSMAKAIG
                     ETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGKGKGRSTAKAGIVE
                     LDMTPKALQQKIHELEEQMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS"
     gene            complement(3123..3809)
                     /gene="bioD"
                     /locus_tag="OPV72_003256"
     CDS             complement(3123..3809)
                     /gene="bioD"
                     /locus_tag="OPV72_003256"
                     /EC_number="6.3.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent dethiobiotin synthetase BioD"
                     /protein_id="HCR9915477.1"
                     /translation="MTKRYFVTGTDTEVGKTVASCALLQAATQLGYQTVGYKPVASGS
                     EMTTDGLRNSDALALQRNSSLPQPYSAINPYTFAEPTSPHIASADEGRAIDAAVLSRG
                     LRTLEAQADWVLTEGAGGWFTPLSATLTFADWVQTEQLPVILVVGVKLGCINHAMLTA
                     LAVEQAGLPLVGWIANDMQPPGARHGEYLATLRRVIPAPLLGEIPWLGVSPSQAATGQ
                     YLDLSPLERA"
     gene            complement(3802..4557)
                     /gene="bioC"
                     /locus_tag="OPV72_003257"
     CDS             complement(3802..4557)
                     /gene="bioC"
                     /locus_tag="OPV72_003257"
                     /EC_number="2.1.1.197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonyl-ACP O-methyltransferase BioC"
                     /protein_id="HCR9915478.1"
                     /translation="MAQVNKQAIAAAFGRAASQYEQHASLQQHSADALLTLLTGRQFA
                     SVLDAGCGPGRMSRYWRERGSEVTALDLSLPMLQQARDRQAAHHYLLADIEAIPHDAE
                     VFDLAWSNLAVQWCGDLRDALSELYRVVRPGGVVAFTTLCQGSLPELRQAWQAVDNRA
                     HANSFLPEEAIDHALRGWRASRHTQAMTLWFEDALSAMRSLKGIGATHLHEGRETDVL
                     TRARLRQIQLAWPQRQGKYLLTYHLFMGVIERD"
     gene            complement(4541..5698)
                     /gene="bioF"
                     /locus_tag="OPV72_003258"
     CDS             complement(4541..5698)
                     /gene="bioF"
                     /locus_tag="OPV72_003258"
                     /EC_number="2.3.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-amino-7-oxononanoate synthase"
                     /protein_id="HCR9915479.1"
                     /translation="MSWQQRVDDALTARRATDTLRRRYVVSQGAGRWLVANGRQYLNF
                     SSNDYLGLSQHPQIIRAWQQAATRFGVGSGGSGHISGYSVAHQALEEELAQWLGYPRA
                     LLFISGFAANQAVITALMKKNDRIVADRLSHASLLEAANLSPAQLRRFIHNDTQHLSR
                     LLQSPCVGQQLVVTEGVYSMDGDSAPLAEIQHIARRHHAWLLVDDAHGIGVTGDEGRG
                     TCWQRGVKPELLVVTFGKGFGVSGAAVLCSESVADYLLQFARHLVYSTSMPPAQAQAL
                     SASLAVIRSDEGRERREKLAALVQRFRAGVNASRFTLLNAHSAIQPLIVGDNSRALRL
                     AEALRQQGCWATAIRPPTVPVGTARLRLTLTQAHEACDIDRLLEVLHGAGE"
     gene            complement(5695..6735)
                     /gene="bioB"
                     /locus_tag="OPV72_003259"
     CDS             complement(5695..6735)
                     /gene="bioB"
                     /locus_tag="OPV72_003259"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HCR9915480.1"
                     /translation="MARHPRWTLSQVTELFEKPLLELLFEAQQIHRQHFDPQQVQVST
                     LLSIKTGACPEDCKYCPQSSRYKTGLEAERLMEVEQVLDSARKAKNAGSTRFCMGAAW
                     KNPHERDMPYLEKIVQGVKAMGLETCMTLGMLNESQAQRLANAGLDYYNHNLDTSPEF
                     YGNIITTRTYQERLDTLEKVREAGIKVCSGGIVGLGETVTDRAGLLLQLANLPTPPES
                     VPINMLVKVKGTPLADNDDVDAFDFIRTIAVARIMMPTSYVRLSAGREQMNEQTQAMC
                     FMAGANSIFYGCKLLTTPNPAEDKDLQLFRKLGLNPQQTRVLAGDNEQQQRLEQTLMT
                     PDTDDYYNAAAL"
     gene            6822..8111
                     /gene="bioA"
                     /locus_tag="OPV72_003260"
     CDS             6822..8111
                     /gene="bioA"
                     /locus_tag="OPV72_003260"
                     /EC_number="2.6.1.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine--8-amino-7-oxononanoate
                     transaminase"
                     /protein_id="HCR9915481.1"
                     /translation="MTTDDLAFDKRHIWHPYTSMTSPLPVYPVERAEGCELVLASGER
                     LIEGMSSWWAAIHGYNHPQLNAAMKAQIDAMSHVMFGGITHQPAVNLCRKLVAITPEP
                     LECVFLADSGSVSVEVAMKMALQYWQARGESRQRFLTFRHGYHGDTFGAMSVCDPDNS
                     MHSLWKGYLPENLFAPAPQSRMDGEWDESDIAPFARLMAAHRHEIAAVILEPIVQGAG
                     GMRIYHPQWLRRIRNMCDREGILLIADEIATGFGRTGKLFACEHAGIAPDILCLGKAL
                     TGGTMTLSATLTTRQVAETISNGEAGCFMHGPTFMGNPLACAVACASLTLLESGEWRQ
                     QVASIESQLRAELAPAQSSPWVADVRVLGAIGVVETTHPVNMAALQRFFVGQGVWIRP
                     FGKLIYLMPPYIIRPDQLRRLTQAVNDAVHNETFFSH"
     gene            8169..8645
                     /locus_tag="OPV72_003261"
     CDS             8169..8645
                     /locus_tag="OPV72_003261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase inhibitor"
                     /protein_id="HCR9915482.1"
                     /translation="MKLISNDLRDGDKLPHRHVFNGMGYDGDNISPHLAWDDVPMGTK
                     SFVVTCYDPDAPTGSGWWHWVVVNLPADTRVLTQGFGSGLVAVPDGVIQTRTDFGKAG
                     YGGAAPPKGETHRYIFTVHALDVERLDVDEDASGAMVGFNVHFHSLASASITAMFS"
     gene            complement(8730..10250)
                     /gene="hutH"
                     /locus_tag="OPV72_003262"
     CDS             complement(8730..10250)
                     /gene="hutH"
                     /locus_tag="OPV72_003262"
                     /EC_number="4.3.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ammonia-lyase"
                     /protein_id="HCR9915483.1"
                     /translation="MNTMTLTPGQLSLSQLYDVWRHPVQLRLDASAIDGINASVACVN
                     DIVAEGRTAYGINTGFGLLAQTRIADEDLQNLQRSLVLSHAAGVGDPLDDAMVRLIMV
                     LKINSLARGFSGIRLSVIEALIALVNAGVYPLIPAKGSVGASGDLAPLAHLSLTLLGE
                     GKARWQGEWLPAQAALKKAGLEPVALAAKEGLALLNGTQASTAFALRGLFEAQELFAS
                     AVVCGALTTEAVLGSCRPFDARIHAARGQQGQIDVARLFRHLLTDTSAIAESHHHCHK
                     VQDPYSLRCQPQVMGACLTQLRQTKEVLLAEANAVSDNPLVFAEAGEVISGGNFHAEP
                     VAMAADDLALAIAEIGALSERRITLMMDKHMSQLPPFLVKNGGVNSGFMIAQVTAAAL
                     ASENKALAHPHSVDSLPTSANQEDHVSMAPAAGRRLWEMAANTRGVIAVEWLAACQGI
                     DLREGLTSSPLLEQARQTLRERVAHYTQDRFFAPDIECATTLLAQGALQRLVPDFM"
     gene            complement(10252..11937)
                     /gene="hutU"
                     /locus_tag="OPV72_003263"
     CDS             complement(10252..11937)
                     /gene="hutU"
                     /locus_tag="OPV72_003263"
                     /EC_number="4.2.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017441920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urocanate hydratase"
                     /protein_id="HCR9915484.1"
                     /translation="MPESKYRQQTIRAPRGTVLTAKSWLTEAPLRMLMNNLDPDVAEN
                     PHELVVYGGIGRAARNWECYDAIVDALTRLEADETLLIQSGKPVGVFKTHDNAPRVLI
                     ANSNLVPHWATWEHFNELDAKGLAMYGQMTAGSWIYIGSQGIVQGTYETFVEAGRQHY
                     NGTLAGRWALTAGLGGMGGAQPLAATLAGACSLTIECQQSRIDFRLRTRYVDEQAATL
                     DDALARITRYTREGKAVSVALCANAADILPELVNRGVRPDLVTDQTSAHDPLHGYLPS
                     GWCWEEYQKNAQSDPRGTMQAAKRSMAAHVRAMLAFSKMGVPTFDYGNNIRQMAKEMG
                     VENAFDFPGFVPAYIRPLFCRGIGPFRWVALSGDPQDIYKTDAKVKEIVAEDKHLHHW
                     LDMARERIHFQGLPARICWVGLEWRQKLGLAFNEMVRCGEVSAPIVIGRDHLDSGSVA
                     SPNRETEAMRDGSDAVSDWPLLNALLNTASGATWVSLHHGGGVGMGFSQHAGMVIVCD
                     GTDEAAARIRRVLHNDPATGVMRHADAGYDLAVECAVEQGLNLPMVAATQGKG"
BASE COUNT         2573 a         3625 c         3205 g         2644 t
ORIGIN      
        1 ataaggatat tctcaacttt aaacaagagg ccatagtcgt cattatttcg gacaaatcat
       61 tcagtatttg cagcgcttga cttataaatg ctcgcgcttc catcacctct tttttaagta
      121 gaatgatgta atctgttgcc atgacacgct ttcaacgaac tcacataaga ttaaaatgac
      181 gatcatgagg atagctatac cgataatacg gggcgttttt tttcatagcc gaggagagag
      241 ggaaaattag cgttgggttc agcctcaacg ctaattttct tcagttgtga ttaaactagc
      301 taccccattg atgttttgac tttttcgaca atctcgttag tcaaagcctg tcactgtttt
      361 tcattcctga ctgacttagc cctgactatt gcactgaaat tctcaaaagc gagccatggt
      421 aacgatgact cgctggcgat cgacacattg tcaggacgcc gcgataaaca actcgcgtaa
      481 ctggtgcaac tggtcgcgaa tttgcgcggc ttcttcaaac tccagatttt gcgcgtgctg
      541 catcatttgc tcttccagtt catgaatttt ctgctgcaac gctttcggcg tcatatccag
      601 ttcgacaatt ccggcttttg ccgtagaacg gcccttgcct ttccccttcg ctttggtttt
      661 cgcaatgttc tgccccagcg ccaggatgtc gaccactttt ttgttcagcc cctgcggagt
      721 gataccgtgc tcttcgttgt acttctgctg cttctcgcga cgtcgctcgg tttcgccaat
      781 cgccttcgcc atcgacggcg tgattttatc gccatacaga atcgctttac cgttaacgtt
      841 acgcgccgcg cgccctatgg tctgaatcag ggagcgctcg gagcgcagga agccctcttt
      901 gtcggcgtcc agaatcgcca ccagcgagac ttccggcata tccagccctt cgcgcagcag
      961 gttaatcccc accagaacgt caaactcgcc cagacgcaaa tcgcggatga tttccatgcg
     1021 ctccacggta tcaatatctg agtgcaggta acgcacgcgc tcgccgtgct cttccagata
     1081 ttcggtcaaa tcttccgcca tccgtttggt gagcgtagtg acaaggacac gctcattaat
     1141 ggccgcacgc tgacgaattt cggacagcag atcgtccacc tgggtcgcca ccggacgcac
     1201 ttcaataatc gggtccagca gcccggtcgg tcgcacgacc tgatccacca cctcatcacc
     1261 agatttttcc agctcatagt tgccgggcgt ggcggaaaca tagatagttt gcggcgctaa
     1321 ggcttcaaac tcctcaaact tcagcggacg gttatccagc gccgaaggca gacggaagcc
     1381 atactcgacc agcgtctctt tgcgcgcccg gtcgccgcgg tacatgccgc ctatctgcgg
     1441 gatggtgaca tgagactcat ccaccaccag cagtccgtcg gcgggcagat aatcgaacaa
     1501 ggttggcggc ggttcgcccg gcccgcggcc cgacagaaag cgggaatagt tttcaatgcc
     1561 tgagcagtag cccagctcgt tcatcatctc taaatcgaac tgcgtgcgct ggcttaatcg
     1621 ctgctcttca agcagcttat tatttgccag caagacctta cgcctgtccg ccagctcatc
     1681 ttttatctct tccatcgcct gcagaatacg ctcgcgcggc gtcacgtagt gcgttttggg
     1741 atagatagta taacgtggca ccgttgactc tacctgcccg gttaacgggt cgaacagcga
     1801 caggcgttcc acttcttcat caaacagctc aacgcgtagc gcaatgtcgt cagattcagc
     1861 cgggaagatg tcgatcactt cgccgcgcac gcgaaaggta ccacgctgaa aagcttgatc
     1921 gttacgggtg tattgcaatt ccgccagccg acgcaaaatc gcgcgctggt caatcagcat
     1981 tcccaccgtc agatgcagca tcattttcag gtagagatcc ggatcgccca gaccgtaaat
     2041 cgcggacacg gaagccacca ccacgacatc gcgtcgctca agcaacgctt tcgttgccga
     2101 caaccgcatt tgctcaatat gttcgtttac cgaagcgtct ttttcgataa acgtatccga
     2161 acttggcaca tacgcttccg gctgatagta gtcatagtag gagacgaaat actccaccgc
     2221 gttttccggg aaaaactctt tcatttcgcc gtagagctgc gccgccaggg ttttattggg
     2281 cgcaagcacc atcgttggcc gctgcaagtc cgcaatgacg ttggcgatgg tgaatgtctt
     2341 cccggagccg gtcacgccca ataacgtctg atgcgccagc ccgtcctcca gcccctcttc
     2401 cagacgacgt atagcgtccg gctgatcgcc agaaggttta aaagcggaat tcagtttgaa
     2461 cggtttactc atgagcggct acctgaagga gtgagcgggc agggatgtaa ttttactctc
     2521 gacggtgaat attgccaata aaaaatactg gatgaaaaaa cagtaacact ccagtgtata
     2581 atggctatcg gcagataccc cacgctattt agaggtaaaa catagacagt cgcggggtaa
     2641 aattccagca gtgtgctggt tatccccaga ccagagtctt ttttaacatt tgtcaagtcg
     2701 gatgatgaaa gttttatgtc aacgtatccc ccttccttta caaccattga ttttatataa
     2761 cttgctgtct aaaaagggat attttctcaa gccgtctttc gcgccaattt agtcgcaggc
     2821 cgcgtcgcct ctcgcttacg ttgtgttttc taactctaat acacaaggtt atccacagga
     2881 atagtggata actgcttcca gcccgtatcc cctgccgcct ggcaaaatca gcccctgacg
     2941 ttttcgccgg gcgataaaaa aaaattatcg ctatttttgg cagattattg gctaacgaga
     3001 aggcaaaaat tgaggcgtag acgctcacat tttgcacatt tttagcatgg cgacgtcagg
     3061 agggtctggc gaaagaacag caggatcgtc tgatcctgca agaaggcggt ttttaagcgc
     3121 ggtcaggcgc gttccaaggg gctaaggtcc agatactgtc ctgtcgccgc ctgcgatgga
     3181 gaaacgccca gccacgggat ttcccctaac agcggggccg gtatgacgcg gcgaagcgtc
     3241 gcgagatatt caccatgacg cgcgcctggc ggctgcatgt cgttggctat ccatccgaca
     3301 agcggtaatc cggcctgttc taccgccagc gccgtcagca tggcgtgatt aatacagccc
     3361 agcttgacgc caacaaccag aatcaccggc agctgctccg tctgtaccca gtcggcaaac
     3421 gtcagcgtgg cagagagcgg tgtaaaccag ccgcccgccc cttctgtcaa cacccagtct
     3481 gcctgcgcct ccagcgttcg taatccgcgt gataacaccg ccgcgtctat cgcccggcct
     3541 tcgtcggcgc tagcgatgtg gggagaagta ggctcggcaa aagtataagg attgatagcg
     3601 gaataaggtt gcggcaggct gctgttacgc tgcaaggcca gggcatcgct attgcgtagc
     3661 ccgtcggttg tcatttcgct gccggaagcg acgggcttat agcctacggt ttgataacct
     3721 aactgcgttg cggcctgcaa taaggcgcaa ctggcgaccg ttttaccgac ttcagtatca
     3781 gtaccggtca caaaatagcg tttagtcacg ttcaatcact cccataaaaa ggtggtacgt
     3841 cagcagatat ttcccctgcc gctgcggcca tgccagttga atctgtctaa gccgggcgcg
     3901 ggttaataca tccgtctccc gcccttcatg aagatgggtg gcgccaatgc ctttgagcga
     3961 acgcatcgcg ctcagggcat cctcaaacca caatgtcatc gcctgagtat gacgagacgc
     4021 ccgccagccg cgtagcgcgt ggtcaatggc ctcttccggc aaaaagctat tcgcgtgagc
     4081 gcgattatcg acggcctgcc atgcctgacg cagctccggc aacgacccct ggcacaaggt
     4141 ggtaaacgcc accacgccgc cgggccgtac aacccgatac aactcgctca acgcatcgcg
     4201 taaatcgccg caccactgga ccgccaggtt gctccaggcc aggtcaaaaa cttcggcgtc
     4261 atggggaatc gcttcgatat ccgccagcaa atagtgatgc gccgcctgac gatcgcgagc
     4321 ctgttgcagc atcggcagcg aaagatccag ggcggtcact tcgctccccc gctctcgcca
     4381 gtaacgactc atacgtccgg ggccgcagcc tgcgtccaac acactggcaa actggcggcc
     4441 tgtcaacagc gtcagcagcg catccgcgct gtgttgctgt aaagaggcgt gctgttcgta
     4501 ttgcgatgcg gcccggccaa acgccgccgc aatagcctgc ttattcacct gcgccatgca
     4561 gcacctccag cagacggtct atatcgcacg cttcatgcgc ctgcgttaac gttaagcgca
     4621 ggcgcgccgt accgacaggc accgtcggcg gacgaatcgc cgtcgcccag catccttgtt
     4681 gacgcagcgc ctccgccagg cgcaatgcac ggctgttatc gcccacgatt aacggctgga
     4741 tggcgctatg ggcattcagt agcgtaaatc gggacgcgtt aacgccggcc cgaaagcgct
     4801 gaaccagagc ggcgagtttt tcgcgccgtt cacgaccttc atcgctacgg atcaccgcca
     4861 gcgaggcgct taacgcctgc gcctgggcgg gcggcatact ggtgctgtaa accagatgac
     4921 gggcgaattg cagcagataa tctgcgacgc tttccgagca gagcaccgct gcgccgctga
     4981 cgccaaaccc cttaccgaaa gtcaccacca gcaactcagg cttcaccccc cgctgccagc
     5041 aggtgccccg cccctcatcg ccagtcacgc cgatgccgtg cgcatcatca accaacagcc
     5101 aggcatgatg cctgcgggca atgtgctgga tttccgccag cggcgcgctg tcgccgtcca
     5161 tgctgtatac accttctgtc accaccagtt gctgacccac gcagggcgat tgcagtaaac
     5221 gcgacagatg ctgcgtatcg ttatggataa agcggcgaag ctgcgccgga ctcagattag
     5281 cggcttccag cagggaagca tgactcaacc tgtcggccac aatccggtca ttttttttca
     5341 ttaaggcggt aatgaccgcc tgattcgccg caaagccaga gataaacagc agcgcgcgtg
     5401 gatatcctaa ccattgcgcc agttcctcct ctaacgcctg gtgcgccacg gaataaccgc
     5461 tgatatgacc cgacccgccg ctgccgacgc caaaacgcgt cgctgcctgt tgccaggcgc
     5521 gaataatctg cggatgttga cttaagccga ggtaatcatt gctggaaaag ttaagatact
     5581 gtcgcccgtt cgctaccagc cagcgtccgg cgccctgcga taccacatag cggcggcgca
     5641 acgtatccgt cgcccgacgc gccgtcagcg catcgtcgac gcgttgttgc caactcataa
     5701 ggctgccgcg ttgtaataat catcggtgtc aggcgtcatc agcgtctgct ccagacgttg
     5761 ctgctgctcg ttatcgcccg ccagcaccct ggtctgctgc ggattcagcc ccagcttacg
     5821 gaataactgc agatccttgt cctctgccgg atttggcgta gttaacaatt tgcagccata
     5881 gaaaatcgag ttcgccccgg ccataaagca catcgcctgg gtctgctcgt tcatctgttc
     5941 acgtcctgcg gaaagacgca cgtatgaggt cggcatcatg atgcgcgcta cggcgatagt
     6001 acgaataaaa tcaaacgcat ccacgtcatc gttatccgca agcggcgtgc cttttacctt
     6061 caccagcatg ttgattggca cgctttccgg cggcgtaggc aggttcgcca actgcaacaa
     6121 cagtccggcg cgatcggtaa ccgtttcgcc cagacccaca atgccgccgg agcacacttt
     6181 aatccctgct tcacggactt tttccagcgt gtcgaggcgc tcctgatagg tacgggtagt
     6241 gatgatattg ccgtaaaact ccggcgaggt atcgaggttg tggttgtagt aatccagccc
     6301 ggcgttagcc agacgctgcg cctggctctc gttcaacatg ccgagcgtca tacaggtttc
     6361 cagccccatc gctttgacgc cctgtacaat cttctccaga taaggcatat cgcgttcatg
     6421 cggattcttc caggccgccc ccatacagaa gcgggtcgaa ccggcgtttt tcgctttacg
     6481 ggcggagtcc agtacctgct ctacctccat taaacgctcg gcttccagcc cggttttata
     6541 gcgcgagctc tgcgggcagt atttacaatc ctccgggcag gcgccggttt tgatcgacaa
     6601 cagcgtacta acctgtacct gctgcggatc gaaatgctgg cgatgaattt gctgcgcttc
     6661 aaacagcaat tccagcagtg gtttttcaaa taattcggtt acttgcgaca gtgtccagcg
     6721 tgggtggcga gccatcgggc ctctccaaaa tatgttgttt gtttttgata tggtgtagac
     6781 tcgtaaacct aaatcttttt aatttggttt acaagtcgat tatgacaacg gacgatctgg
     6841 ccttcgataa acgccatatt tggcatcctt acacttccat gacctcgccg ctgccggtat
     6901 atcccgttga gcgggccgaa ggctgcgagc tggttctcgc ctcgggcgaa cgcctgattg
     6961 aggggatgtc ctcctggtgg gcggccattc atggttataa ccacccgcaa ttgaacgcgg
     7021 cgatgaaagc gcaaattgac gccatgtcgc atgtcatgtt cggcggcata acccatcaac
     7081 ctgcggtgaa tctgtgccgt aagctggtcg cgataacgcc tgagccgctg gagtgtgtct
     7141 ttctggccga ctctggttcg gtgtcggtag aagtggccat gaagatggcg ctgcaatact
     7201 ggcaggctcg tggcgaatcg cgtcagcgtt ttctgacgtt tcgccacggt tatcatggcg
     7261 acacgttcgg cgcgatgtcg gtgtgcgatc cggataactc catgcacagc ttgtggaaag
     7321 gctatctgcc tgaaaatctg ttcgcgccgg cgccgcaaag ccggatggat ggcgaatggg
     7381 atgaaagcga catcgcgcca tttgcccgcc tgatggccgc gcatcgccat gaaatagccg
     7441 ccgtgattct ggaacctatc gttcagggcg cgggcgggat gcgcatatat catccacaat
     7501 ggctcaggcg tattcgtaac atgtgcgatc gcgaaggcat tctgctgatt gccgatgaaa
     7561 tagccaccgg gtttggccgt accggcaaac tgttcgcctg tgagcacgcc gggatcgcgc
     7621 cggatattct gtgtctcggc aaagccttaa ccggcggtac catgaccctc tcggcaacgc
     7681 tcacgacacg ccaggttgca gagactatta gcaacggcga ggcggggtgt tttatgcatg
     7741 gcccgacgtt tatggggaat ccgctggcct gcgccgtcgc ttgcgccagc ctgacgctgc
     7801 tggaaagcgg cgaatggcgt cagcaggtgg cgtctatcga gtctcagtta cgcgctgagt
     7861 tagcccccgc gcaaagttcg ccctgggtgg cggatgtgcg ggtgttgggc gcgattgggg
     7921 tggttgaaac tacgcatccg gtcaatatgg cggcgcttca acgcttcttc gtcgggcaag
     7981 gcgtctggat caggccgttc ggcaagctaa tctacctgat gccgccctac attattcgtc
     8041 cggatcaact gcgccgtttg acccaggcgg tcaatgacgc ggtacacaat gaaacatttt
     8101 ttagccatta atcagcggta agcgatgctg cttctggcta cacttctggt gagtcaaaag
     8161 gagagcgcat gaaacttatc agcaacgatt tgcgcgatgg agataaactt cctcatcgcc
     8221 acgtttttaa cggtatgggc tatgatggcg ataatatttc gccgcatctg gcctgggacg
     8281 acgtgccgat gggcaccaaa agttttgtcg tgacctgtta cgatcctgac gcgccgaccg
     8341 gctccggctg gtggcactgg gtggtggtga acctcccggc ggatacgcgc gtactgaccc
     8401 aggggttcgg ctcaggcctg gtggccgtac cagacggcgt cattcagacg cgtaccgatt
     8461 tcggtaaagc gggctacggc ggcgcggcgc cgcctaaagg ggaaacgcac cgctatatct
     8521 ttacggttca cgcgctggac gtcgagcgtc ttgacgttga tgaagacgcc agcggcgcga
     8581 tggtcggctt taacgtgcat ttccattcgc tcgccagcgc ctcgataacg gcgatgttca
     8641 gttaaacgct gtgtcggatg gcggcataaa cgtcttaccc ttccaacggg ttgggtaagc
     8701 cgaatacgtg ccgcgccatc cggcaacatt cacataaagt ccggcaccag acgctgtaac
     8761 gcgccttgcg ccagcagcgt cgtcgcacac tcaatatcgg gcgcgaaaaa acgatcctgc
     8821 gtatagtgcg ccacccgctc gcgcagtgtc tgccgcgcct gttccagtaa cgggctggag
     8881 gttaaccctt cccgtaaatc tatcccctga caggcagcca gccactccac ggcaatgacg
     8941 ccgcgggtat tcgccgccat ttcccagagt cgccgtcccg ccgccggggc cattgagaca
     9001 tgatcttcct gattcgccga ggtcggcagg ctatccacgc tgtgcgggtg cgccagcgct
     9061 ttattctcgc tggcaagcgc cgcggcggtg acctgggcaa tcataaaacc ggaattaacg
     9121 ccgccatttt tcaccaggaa cggcggtaac tgcgacatat gtttatccat catcagcgtg
     9181 atgcgccgct ccgatagcgc gccgatttcc gctatcgcca gcgccagatc atccgccgcc
     9241 atggcaaccg gttcagcatg gaagttaccg ccggagatca cctcccccgc ctcggcaaag
     9301 accagcggat tatcggacac cgcattggcc tcagccagca gtacctcttt cgtctgacgt
     9361 aactgggtca gacaagcgcc cattacctgc ggctggcagc ggagggaata cgggtcctga
     9421 actttatgac agtggtgatg tgattcagca atggcgctgg tatcggtcag cagatgccgg
     9481 aacaaccgcg cgacgtcaat ttgcccctgt tgtccgcgcg cggcatgaat gcgcgcatca
     9541 aaaggacggc acgatcccag tacggcttcg gtagtcagcg cgccgcagac gacggcggag
     9601 gcaaataatt cctgtgcctc aaacaaaccg cgcagcgcga aggccgtcga cgcctgggtg
     9661 ccgttaagca gcgccagccc ctctttggcc gccagcgcga caggttccag tccggccttt
     9721 tttagcgccg cctgcgccgg aagccattcg ccctgccagc gcgcttttcc ttcgccaagt
     9781 agcgtcagcg acagatgcgc cagaggcgct aagtcgcccg acgcgccaac cgaccctttt
     9841 gccggaatca gcggatacac gccggcattc accagagcga tgagcgcctc tatcacgctc
     9901 aaccgaatcc cggaaaaccc gcgcgccagg ctattgattt tcaataccat gatcagacgc
     9961 accatcgcgt catccagtgg gtcgcctacg cccgcggcgt gagacagcac caacgatcgc
    10021 tgtagatttt gcaagtcttc atcagcgatg cgcgtctgcg ccagcaggcc gaaaccggtg
    10081 ttgatgccgt aggcggtacg cccttcggca acaatatcat tgacgcacgc aacactggcg
    10141 ttaatgccgt caatggcgct ggcgtccagc cgaagctgta ccggatgacg ccagacatcg
    10201 tacagttgag agaggcttaa ctgccccgga gtgagtgtca tggtgttcat atcagccttt
    10261 cccctgcgtc gccgcaacca tcggtaaatt cagaccttgc tcaacagcgc attccaccgc
    10321 gagatcatat ccggcatcgg catgacgcat gacgcccgtc gccggatcgt tgtgtaacac
    10381 gcggcgaata cgcgcggcgg cctcgtcagt gccatcacag acaatcacca taccggcgtg
    10441 ttgcgaaaaa cccatcccca ccccgccgcc atgatggagc gatacccatg tcgccccgct
    10501 ggcggtattc agcaacgcat ttaacagcgg ccagtcggaa accgcgtcgg aaccgtcgcg
    10561 catcgcttcg gtttcacggt tagggctggc gacagaaccg gaatccaggt gatcgcggcc
    10621 aatcacaatg ggcgcggata cctcgccgca acgcaccatt tcgttgaacg ccagccccag
    10681 tttttgccgc cactccaagc ctacccagca gatacgcgcc ggtagcccct gaaaatgaat
    10741 gcgctcacgc gccatatcca gccagtgatg cagatgttta tcctcagcca ctatctcttt
    10801 gactttggca tcggttttat agatatcctg cggatcgccg gacagcgcca cccagcgaaa
    10861 cggcccgatg ccacgacaga acagcggacg aatataggct ggcacaaatc ccggaaaatc
    10921 aaaggcgttt tccaccccca tctctttcgc catctggcga atattgttgc catagtcaaa
    10981 ggtcggcacg cccattttac tgaacgccag catcgcccga acatgcgccg ccatggaacg
    11041 tttcgctgcc tgcatcgtcc cccggggatc ggattgcgcg tttttctgat actcctccca
    11101 gcaccagccg gagggcaaat agccatgtag cggatcgtgg gcgctggtct gatcggtcac
    11161 caggtccggg cgcacgccgc gattaaccag ttccggcagg atatccgccg cgttcgcgca
    11221 cagggcgacg gacacggctt tcccctcgcg ggtgtagcgc gtaatgcggg ccagcgcgtc
    11281 atccagcgtg gcggcctgct catccacgta gcgagtacgc agacgaaaat cgatacggct
    11341 ttgctggcat tcaatcgtca gcgaacacgc tccggccagc gtcgcggcta gcggttgcgc
    11401 gccgcccatg ccgcccagcc cggcggtcag cgcccagcgt cccgccagcg tgccgttata
    11461 gtgctgacgc cccgcctcga caaaggtttc gtatgttccc tgcacgattc cctgactacc
    11521 gatatagatc cagcttccgg ccgtcatttg accgtacatc gccagccctt tcgcatccag
    11581 ttcgttaaag tgttcccatg tcgcccagtg gggaaccagg ttggagttgg cgattaatac
    11641 ccgcggcgcg ttgtcgtgcg ttttaaatac gccgaccggt ttgccagact gaatcagcaa
    11701 cgtttcgtcc gcctccagcc gggtgagcgc atcaacaata gcgtcatagc attcccagtt
    11761 gcgcgcggcg cgaccaatcc cgccgtagac caccagctca tgcggatttt ccgccacgtc
    11821 aggatcgaga ttattcatta acatccgcag cggggcttct gtcagccagc ttttcgccgt
    11881 taataccgtg cctcggggcg cgcggatagt ctgctgacga tacttgcttt caggcatagc
    11941 aatgactcct cattattatc ggtctgccat cgccaaataa cgctaaaacg ccactatcag
    12001 gcaccgccgc agacccacag ataagaatca gacatatact tatctat
//
LOCUS       DAJVBX010000145        12010 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.145, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000145 DAJVBX010000000
VERSION     DAJVBX010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 12010)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12010)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12010
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.145"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(76..591)
                     /gene="luxS"
                     /locus_tag="OPV72_003264"
     CDS             complement(76..591)
                     /gene="luxS"
                     /locus_tag="OPV72_003264"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008458247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HCR9915485.1"
                     /translation="MPLLDSFAVDHTRMQAPAVRVAKTMNTPHGDAITVFDLRFCIPN
                     KEVMPEKGIHTLEHLFAGFMRDHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVAD
                     AWKAAMADVLKVQDQNQIPELNVYQCGTYQMHSLSEAQDIARHILERDVRVNSNKELA
                     LPKEKLQELHI"
     gene            complement(741..2297)
                     /gene="gshA"
                     /locus_tag="OPV72_003265"
     CDS             complement(741..2297)
                     /gene="gshA"
                     /locus_tag="OPV72_003265"
                     /EC_number="6.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--cysteine ligase"
                     /protein_id="HCR9915486.1"
                     /translation="MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTVH
                     PEALGSALTHKWITTDFAEALLEFITPVDGDIQHMLTFMRDLHRYTARKLGDERMWPL
                     SMPCYIAEGQDIELAQYGTSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFW
                     QAKCGVTEGEAAKEKISAGYFRLIRNYYRFGWVIPYLFGASPAICSSFLQGKPTTLPF
                     EKTDCGMYYLPYATSLRLSDLGYTNKSQSNLGITFNDLHEYVAGLKRAIKTPSEEYAR
                     IGVEKDGKRLQINSNVLQIENELYAPIRPKRVTRSGESPSDALLRGGIEYIEVRSLDI
                     NPFSPIGVDEQQVRFLDLFMVWCVLADAPEMSSDELLCTRTNWNRVILEGRKPGLTLG
                     IGCETAQFPLPKVGKDLFRDLKRVAQTLDSIHGGEEYQKVCDELVACFDNPELTFSAR
                     ILRSMIDEGIGGTGKAFGEAYRNLLREEPLEILQEEEFIAERDASVRRQQEIEAADTE
                     PFAAWLAKHA"
     gene            complement(2374..2799)
                     /locus_tag="OPV72_003266"
     CDS             complement(2374..2799)
                     /locus_tag="OPV72_003266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HCR9915487.1"
                     /translation="MSDGLSLLSLFASSFLSATLLPGNSEVVLVAMLVSGVSHPWVLV
                     LTATMGNSLGGVTNVILGRFFPLRKTSRWQEKATGWLKRYGAATLLLSWMPVIGDLLC
                     LLAGWMRIPWGRTIFFLCLGKALRYVALAAATVQGMMWW"
     gene            complement(2796..3362)
                     /gene="yqaB"
                     /locus_tag="OPV72_003267"
     CDS             complement(2796..3362)
                     /gene="yqaB"
                     /locus_tag="OPV72_003267"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-1-phosphate/6-phosphogluconate
                     phosphatase"
                     /protein_id="HCR9915488.1"
                     /translation="MYARYAGLIFDMDGTLLDTEPTHRKAWREVLGRYGLRFDEQAMV
                     ALNGSPTWLIAQSIIELNHADLDPLSLAREKTDAVKSILLDCVEPLPLVEVVKAWHGR
                     RPMSVGTGSESAIAEALLAHLGLRRYFDAVVAADHVQHHKPAPDTFLLCAQRMGVMPT
                     QCVVFEDADFGLQAARAAGMDAVDVRLL"
     gene            complement(3733..3809)
                     /locus_tag="OPV72_003268"
     tRNA            complement(3733..3809)
                     /locus_tag="OPV72_003268"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3773..3775),aa:Arg,seq:acg)
     gene            complement(4006..4082)
                     /locus_tag="OPV72_003269"
     tRNA            complement(4006..4082)
                     /locus_tag="OPV72_003269"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(4046..4048),aa:Arg,seq:acg)
     gene            complement(4145..4221)
                     /locus_tag="OPV72_003270"
     tRNA            complement(4145..4221)
                     /locus_tag="OPV72_003270"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(4185..4187),aa:Arg,seq:acg)
     gene            complement(4284..4361)
                     /locus_tag="OPV72_003271"
     tRNA            complement(4284..4361)
                     /locus_tag="OPV72_003271"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(4324..4326),aa:Arg,seq:acg)
     gene            complement(4365..4457)
                     /locus_tag="OPV72_003272"
     tRNA            complement(4365..4457)
                     /locus_tag="OPV72_003272"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(4421..4423),aa:Ser,seq:gct)
     gene            complement(4761..4946)
                     /gene="csrA"
                     /locus_tag="OPV72_003273"
     CDS             complement(4761..4946)
                     /gene="csrA"
                     /locus_tag="OPV72_003273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon storage regulator CsrA"
                     /protein_id="HCR9915489.1"
                     /translation="MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHR
                     EEIYQRIQAEKSQQSSY"
     gene            complement(5181..7811)
                     /gene="alaS"
                     /locus_tag="OPV72_003274"
     CDS             complement(5181..7811)
                     /gene="alaS"
                     /locus_tag="OPV72_003274"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HCR9915490.1"
                     /translation="MSKSTAEIRQAFLDFFHSKGHQVVASSSLVPNNDPTLLFTNAGM
                     NQFKDVFLGLDKRNYSRATTSQRCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDY
                     FKHDAIQFAWELLTGENWFALPKERLWVTVYETDDEAYEIWEKEVGIPRERIIRIGDN
                     KGAPYASDNFWQMGDTGPCGPCTEIFYDHGDHIWGGPPGSPEEDGDRYIEIWNIVFMQ
                     FNRQADGTMEPLPKPSVDTGMGLERIAAVLQHVNSNYDIDLFRTLIEAVAKVTGSTDL
                     GNKSLRVIADHIRSCAFLVADGVLPSNENRGYVLRRIIRRAVRHGNMLGAKETFFYKL
                     VGPLIEVMGSAGEELKRQQAQVEQVLKTEEEQFARTLERGLALLDEELAKLQGDTLDG
                     ETAFRLYDTYGFPVDLTADVCRERNIKVDEAGFEAAMEEQRRRAREASGFGADYNAMI
                     RVDSASEFKGYDHLELNGKVTALFVDGKAVEAINAGQEAVVVLDQTPFYAESGGQVGD
                     KGELKGAGFTFAVDDTQKYGQAIGHLGKLSAGALKVGDAVQADVDEARRARIRLNHSA
                     THLMHAALRQVLGTHVAQKGSLVSDKVLRFDFSHNEAMKPSEIREVEDLVNAQIRRNL
                     PIETNIMDLDAAKAKGAMALFGEKYDERVRVLSMGDFSTELCGGTHASRTGDIGLFRI
                     ISESGTAAGIRRIEAVTGEGAMATVHAQSDRLNDIAHLLKGDSQNLGDKVRAVLERTR
                     QLEKELQQLKDQAAAQESANLSSKAVDLNGVKLLVSELAGIEPKMLRTMVDDLKNQLG
                     STVIVLATVVEGKVSLIAGVSKDVTDRVKAGELIGMVAQQVGGKGGGRPDMAQAGGTD
                     AAALPAALASVQGWVSAKLQ"
     gene            complement(8047..8547)
                     /gene="recX"
                     /locus_tag="OPV72_003275"
     CDS             complement(8047..8547)
                     /gene="recX"
                     /locus_tag="OPV72_003275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HCR9915491.1"
                     /translation="MSEPTSRRPAYARLLDRAVRILAVRDHSEQELRRKLSAPVMGKN
                     GPEEIDATADDYERVIAWCHEHHYLDDERFVMRFIASRSRKGYGPARIRQELNQKGIS
                     RESTEKAMRECEIDWSEMAREQAVRKYGEPLPSNFSEKVKVQRFLLYRGYLMDDIQQI
                     WRNFAD"
     gene            complement(8664..9725)
                     /gene="recA"
                     /locus_tag="OPV72_003276"
     CDS             complement(8664..9725)
                     /gene="recA"
                     /locus_tag="OPV72_003276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HCR9915492.1"
                     /translation="MAIDENKQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTG
                     SLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDP
                     VYARKLGVDIDNLLCSQPDTGEQALEICDALARSGAVDVIVVDSVAALTPKAEIEGEI
                     GDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFINQIRMKIGVMFGNPETTTGGNALKF
                     YASVRLDIRRIGAVKEGDNVVGSETRVKVVKNKIAAPFKQAEFQILYGEGINFYGELV
                     DLGVKEKLIEKAGAWYSYNGEKIGQGKANATTWLKENPATAKEIEKRVRELLLSNQNA
                     TPDFAVDDSEGVAETNEDF"
     gene            complement(9810..10307)
                     /gene="pncC"
                     /locus_tag="OPV72_003277"
     CDS             complement(9810..10307)
                     /gene="pncC"
                     /locus_tag="OPV72_003277"
                     /EC_number="3.5.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide-nucleotide amidase"
                     /protein_id="HCR9915493.1"
                     /translation="MTDSELMRLSEQVGLALKARGATVTTAESCTGGWLAKAITDIAG
                     SSAWFERGFVTYSNEAKAQMIGVREETLAQHGAVSESVVVEMAIGALKAARADFAVAI
                     SGIAGPDGGSEEKPVGTVWFAFASVSGEGITRRECFSGDRESVRRQATTYALQTLWQQ
                     FLQNT"
     gene            complement(10773..11852)
                     /gene="mltB"
                     /locus_tag="OPV72_003278"
     CDS             complement(10773..11852)
                     /gene="mltB"
                     /locus_tag="OPV72_003278"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic murein transglycosylase B"
                     /protein_id="HCR9915494.1"
                     /translation="MFKRRYVALLPLCVLLAACSSTPKSSETQATTGTPSGGFLLEPQ
                     HNVMQMGGDFANNPNAQQFIDKMVSKHGFDRQQLQEILSQSKRLDYVLRLMDRQAPTT
                     QPPAGPNGAWLRYRKQFITPDNVQNGVAFWNQYEDALNRAWQVYGVPPEIIVGIIGVE
                     TRWGRIMGKTRILDALATLSFNYPRRAEYFSGELETFLLMARDEQDDPLNLKGSFAGA
                     MGYGQFMPSSYKEYAVDFNGDGHINLWDPVDAIGSVANYFKAHGWVKGDMVAVPASGQ
                     APGLANGFKTKYSISQLAAAGLTPQQSLGNHQEASLLRLDIGTGYQYWYGLPNFYTIT
                     RYNHSTHYAMAVWQLGQAVALARVR"
BASE COUNT         2830 a         3410 c         2911 g         2859 t
ORIGIN      
        1 aattatatta agcaataaaa aaccccggcc ataaaccggg gttaatttaa atactggaac
       61 cgcttaccaa taagactaaa tatgcaattc ctgcagtttt tctttcggca gcgccagctc
      121 tttattgctg ttcacgcgca catcacgctc cagaatatga cgggcaatgt cctgcgcttc
      181 actgagcgag tgcatctgat acgtaccgca ctggtaaacg ttcagctccg ggatctggtt
      241 ttgatcctgc actttcagca catccgccat cgccgctttc caagcgtcgg caacacgctg
      301 ctcgtccggc gtgccaatca ggctcatgta aaagccggtg cggcagccca tcggcgagat
      361 atcgataatc tcaacgccgt taccgttgag gtggtcgcgc ataaagccag caaacagatg
      421 ctcaagcgta tgaatccctt tttccggcat cacttctttg ttcggaatgc aaaaacgcag
      481 atcaaacacg gtgattgcgt cgccatgcgg ggtgttcatc gtttttgcaa cccggaccgc
      541 cggcgcttgc atccgggtat gatcgactgc gaagctatct aataatggca tttagtcacc
      601 tccgataatt ttttaaaaat aaactgaact ctttgttccg gggcgagtct gagtatatga
      661 aagacgcgca tttgttatca tcatccctgt tttcagcgat gaaattttgg ccactccgtg
      721 agtggccttt ttcttttggg tcaggcgtgt ttcgcaagcc acgcggcaaa cggctcggta
      781 tccgccgcct caatctcctg ctgacgacgt actgaagcgt cacgttcagc aataaactct
      841 tcttcctgta aaatctccag cggctcttcg cgtaacagat tacggtaagc ctcaccgaac
      901 gctttcccag tgccgccaat gccttcatca atcatagacc gtaagattcg ggcagagaat
      961 gtcagttcag gattatcaaa gcaggcgacc aactcatcac acaccttttg atactcctct
     1021 cccccgtgga tactgtccag cgtttgcgcc acgcgtttca gatcgcggaa gagatctttc
     1081 cctactttag gcagcgggaa ctgcgcggtt tcacagccaa tccccagggt aaggcccggc
     1141 ttacgccctt ccagaataac gcgattccag ttagtacgcg tacataacag ctcatcgcta
     1201 ctcatttccg gcgcatcggc caatacgcac cagaccataa acagatcgag gaagcgcacc
     1261 tgttgctcgt ctacgccgat cggtgagaac ggattaatat cgagagaacg aacttcgatg
     1321 tactcaatac caccacgcag aagcgcatct gaaggcgatt cgccgctgcg cgtcacgcgc
     1381 ttgggacgaa tgggcgcgta cagctcattt tcaatttgca gaacgttgct gttaatctgt
     1441 agccgcttac cgtctttttc cacaccaatc cgcgcgtact cttctgacgg cgttttaatc
     1501 gcccgtttca gacctgcaac gtattcatgt agatcgttaa acgtaatacc cagattgctt
     1561 tgcgacttat tggtatagcc caaatcactc aaacgcagcg acgtcgcata tggcaggtag
     1621 tacatgccgc agtccgtttt ttcaaacggt aatgtggttg gcttcccttg caggaaagag
     1681 gaacaaatgg ccggagacgc gccaaacaga taggggatga cccagccaaa acggtaatag
     1741 ttgcgaatca gacgaaaata gccggcagaa attttttctt ttgccgcttc gccttccgta
     1801 acgccgcatt tcgcctgcca gaacgccatc ggtaatgaaa aattgtaatg tacgccggaa
     1861 atggtttgca tcaaagcgcc ataacgattt ttcagccctt cgcgatagag cgtcttaaag
     1921 cgcccggtat ttgatgtgcc gtactgcgcc agctctatgt cctgcccttc cgcaatatag
     1981 cagggcatac ttaatggcca catccgctca tcgcccagtt tcctggccgt ataccgatgg
     2041 agatcgcgca taaaggtgag catatgctgg atatcgccat cgactggcgt aataaactcc
     2101 agtagggctt ccgcaaaatc tgtggtaatc catttatggg tcagcgctga acctaacgct
     2161 tcaggatgaa ctgttgtcgc cagcgtgcca tcagcattga cacgcagcgt ttcgcgctct
     2221 aacccgcgct gtatcccctt taacgcctga ggatgttttt ccagccaggc cagagcctgt
     2281 gatacgtccg ggatcaaatt gacctcccgc ctgtccaaat cgttttaata agcataactg
     2341 taatggcggc catacatgcc aaacctacaa ttattaccac cacatcatgc cctgaaccgt
     2401 cgccgctgcg agcgcaacat agcgcagcgc cttaccaaga cacaaaaaaa agatcgtccg
     2461 cccccacggg atgcgcatcc atcccgctaa caggcacaac aaatcaccga tgaccggcat
     2521 ccagcttaat aatagtgtgg ctgcgccata acgctttagc cagccagtcg ctttttcctg
     2581 ccaacgcgac gttttgcgca gcggaaagaa acgcccaaga ataacgttag ttacccctcc
     2641 aaggctatta cccattgttg ctgttaagac taagacccag ggatgactga cgccggagac
     2701 cagcatagca accaaaacca cctcagaatt accgggtaac agcgtcgcgc tgagaaaact
     2761 actggcaaac agagacagga gcgacagtcc gtcactcaca atagtcggac atccacggca
     2821 tccattcccg ccgcccgcgc cgcctgtaaa ccaaaatcgg catcttcaaa taccacgcac
     2881 tgcgtcggca tgacgcccat ccgctgggcg cacaatagga aggtgtcagg cgcaggtttg
     2941 tgatgctgta cgtgatctgc cgccacaacc gcatcaaaat aacgacgcag ccccagatgc
     3001 gctaacaagg cttccgcgat agcgctttcg ctaccggtac cgaccgacat gggacgccgc
     3061 ccatgccacg ctttgaccac ctcaaccagc ggcagcggtt ctacgcagtc cagcaggatg
     3121 ctttttaccg cgtcggtttt ctcacgcgcc agtgacaggg gatcaagatc ggcatggtta
     3181 agctcaatga ttgactgggc gataagccag gttggcgaac cgttaagcgc gaccattgcc
     3241 tgttcatcaa aacgaagacc atagcgcccc aaaacctcac gccacgcttt gcgatgcgtg
     3301 ggttcggtat ccaggagagt accgtccata tcaaaaatca aaccagcata acgtgcgtac
     3361 atcgtgttct cgcaaaccga ataaccagac agtactttat cgcaattggt tgattttgtc
     3421 gctaatagag atgaagaggt atattcagga taagggggaa aagcgattgc agggcagtaa
     3481 cgtatccggg aggattactc gcccttcggg ccgttgctga tgcaacgtta tccttctgat
     3541 gccagcggtg attaccgcta tcttatctgc atcttcatcg ctgaaagtat ggagaatatg
     3601 gtgcatccgg gaggattact cgccttacgg ctcgcccttc gggccgttgc tgacgcaacg
     3661 ttatccttcc tggtgcctgc ggtgattacc gctatcttat ccgcatcttt atcgctgaaa
     3721 gtatggagaa tatggtgcat ccgggaggat tcgaacctcc gaccgctcgg ttcgtagccg
     3781 agtactctat ccagctgagc tacggatgca ttgggaaact tgctttactg ctgatattga
     3841 taccgcggtg aaagccgtat caattaagag atggtgtatc cgggaggatt actcgcctta
     3901 cggctcgccc ttcgggccgt tgctaacgca acgttatcct tcctggtgcc agcggtgatt
     3961 accgctatct tatccgtatc ttcatcgctg aaagtacgga gaatatggtg catccgggag
     4021 gattcgaacc tccgaccgct cggttcgtag ccgagtactc tatccagctg agctacggat
     4081 gcatcggaaa acttgcttta ctgccgatat tgataccgcg gtgaaagccg tatcaagtaa
     4141 gagatggtgc atccgggagg attcgaacct ccgaccgctc ggttcgtagc cgagtactct
     4201 atccagctga gctacggatg catcgggaaa cttactttac tgcagatttt gataccgcgg
     4261 tgaaagccgt atcaagtaag agatggtgca tccgggagga ttcgaacctc cgaccgctcg
     4321 gttcgtagcc gagtactcta tccagctgaa gctacggatg caaatggcgg tgaggcgggg
     4381 attcgaaccc cggatgcagc ttttgaccgc atactccctt agcaggggag cgccttcagc
     4441 ctctcggcca cctcaccaca cgcctcttac gagtgcttcg aagaacttgt tctgctcatc
     4501 gtcgctgcgt ggcgcacata ttactttctg ggacttataa gtcaaacaat ttttccagag
     4561 cttttatcgt ttgcacactt cacgctcaat tagtctataa aaaagccaaa aagagtgttt
     4621 tatcaacaga taatttgatg acacgctggc cgccaaaagc gcaccatatc aacagtgagg
     4681 ttgaaaaaag tcatgagggg acaacgcggg cgagcgagaa gagaggctgc gtctcacccg
     4741 aaaagtgaga cgcgaaaacc ttagtaactg gactgctggg atttttcagc ctggatacgc
     4801 tggtagatct cttcacgatg gacagaaact tctttcgggg cgttcacgcc aatacgcacc
     4861 tggttgccct tcacccctaa aactgtcacg gtgacctcat cgccaatcat gagggtctca
     4921 ccaactcgac gagtcagaat cagcattctt tgctccttga aagattaaaa gagtcgggtc
     4981 tctctgtatc ccggcattat ccatcatata acgccaaaaa gtaagcgatg acaaacacct
     5041 taggtgtaag cagtcatggc attacattct gttaaaccta agtttagccg atatacaaaa
     5101 cttcaacctg actttatcgt tgtcgatagc gttgacgtaa acgccgcagc acgagctgcg
     5161 gcgccaacga acgcttataa ttattgcaat tttgcgctga cccagccttg tacactggct
     5221 aacgctgcag gcagagctgc cgcatccgta ccaccggctt gcgccatgtc cggacgaccg
     5281 ccacccttac cgcccacctg ctgagcgacc ataccaatca attcccctgc tttaacccgg
     5341 tcggtcacat ccttcgacac gcccgcaatc agagaaacct taccttcaac aaccgttgcc
     5401 agtacgataa cggtagaccc cagttgattt ttcagatcat caaccatggt tcgcagcatt
     5461 ttcggctcaa taccagcaag ctcgctgacc aggagcttca cgccgttgag atcgaccgct
     5521 ttactggaaa gatttgcact ctcctgcgct gcggcctggt ccttcaactg ctgcaactct
     5581 ttttccagct gacgcgtacg ttccagcacg gcacgcactt tgtcgcccag attctggctg
     5641 tcgcccttca gcagatgcgc aatatcgttt aagcgatcgc tttgcgcgtg aacggtggcc
     5701 atagcgcctt caccggttac cgcctcaata cgacgaatgc ccgctgcggt gccggactca
     5761 gagataatac ggaatagacc gatatcaccg gtacgactgg cgtgagtacc gccgcacagt
     5821 tcggtagaga aatcgcccat gctcagaacg cgtacacgtt cgtcgtattt ctcgccaaac
     5881 agcgccatgg cccctttcgc cttcgccgcg tcgagatcca tgatgttcgt ttcaatcggc
     5941 aggttgcggc gaatttgcgc attcaccaaa tcttcaacct cacgaatctc cgacggcttc
     6001 atcgcttcat tgtgcgagaa gtcgaagcgc agcactttat cgctaaccag cgaacctttc
     6061 tgcgcaacgt gtgtcccaag cacctggcgc aacgccgcgt gcatcaggtg cgtggcggag
     6121 tggttcagac ggatacgtgc gcggcgcgct tcatctacgt cagcctgtac cgcatcgccc
     6181 actttcagag cgcccgcaga caatttgccg aggtgaccaa tcgcctgacc atatttttgc
     6241 gtgtcgtcca cagcgaaagt aaatccagcg cctttcagct cgcctttatc gccaacctga
     6301 ccgcctgatt ccgcatagaa tggggtctga tccagcacga caacagcttc ctgtcccgcg
     6361 ttaatcgctt caaccgcttt accatcgaca aacagcgcag tcactttgcc gttcagttcc
     6421 agatggtcat aacctttaaa ttcagaagcg ctgtcaacgc ggatcatcgc gttgtagtcc
     6481 gcgccaaaac cgctagcttc gcgcgcgcga cggcgttgct cttccatggc ggcttcaaaa
     6541 ccggcttcgt cgactttgat gttgcgctca cggcagacgt ccgccgttag atcgaccggg
     6601 aaaccataag tatcatacag acggaaagcg gtttcgccgt ccagggtgtc gccctgcaat
     6661 ttcgccagtt cttcatccag cagcgccaga ccgcgctcca gcgtacgagc gaactgctct
     6721 tcttccgttt tcagaacctg ctcgacctgc gcctgctgac gtttcaactc ttcgcctgcg
     6781 gagcccatta cctcaatcag cggcccaacc agcttgtaga agaaggtctc ttttgcgccc
     6841 agcatgttgc cgtgacgaac cgcgcgacga ataatgcgac gcagcacata gccacggttt
     6901 tcattcgacg gcagcacgcc atcggcaacc aggaatgcgc aagaacggat gtggtcggcg
     6961 ataacgcgca gcgatttatt acccaaatcg gtggagccgg tgactttcgc taccgcttca
     7021 atcaacgtgc ggaacaggtc gatgtcatag ttagagttaa cgtgttgcag taccgcggca
     7081 atacgctcca gccccatacc ggtatctaca gacggtttcg gcaatggttc catcgtcccg
     7141 tcagcctgac ggttgaactg cataaagacg atgttccaga tttcaatata gcgatcgccg
     7201 tcttcttccg ggcttcccgg agggccgccc cagatgtggt cgccatgatc gtagaagatt
     7261 tcggtgcacg gaccgcaggg accggtgtcg cccatctgcc agaagttatc cgatgcgtat
     7321 ggcgcgcctt tattgtcacc gatacggatg atacgctcgc gcgggatgcc gacttctttt
     7381 tcccagatct cataggcttc gtcgtcggtt tcatagacgg tgacccataa gcgctctttt
     7441 ggcagagcaa accagttttc gccggtcagt aattcccatg cgaactgaat ggcgtcgtgt
     7501 ttgaaataat cgccgaagct gaagttgccc agcatttcga agaaagtatg gtgacgtgca
     7561 gtgtatccga cgttttccag atcgttgtgt ttaccccccg cgcgtacgca acgctgggaa
     7621 gtggttgcac gggaataatt acgtttatcg agcccaagga aaacatcctt gaactggttc
     7681 atcccggcat tggtaaacaa cagagtgggg tcattgttag gcaccaggga actgctggca
     7741 actacctgat gccctttact atggaaaaag tcgagaaacg cctgacggat ctcagcggtg
     7801 ctcttgctca taattatcct gaaatcaagc tacactccat ccttcaggcc gcctctgcgt
     7861 tggctgcgag tttcccggtc acgcgttccc gaggctcact tgccgcttta atgcggcttg
     7921 aatgattttg tgtatttaag gaatattcgt cgcagacgct gttcgccgtt aagcaacccg
     7981 cgtccagacg gaaaaagtgg gaataagata agttttcttt accgggaagt aaaatcccgt
     8041 atgcgctcaa tctgcaaaat ttcgccatat ttgctggata tcgtccatca gatacccgcg
     8101 atagagcaaa aagcgctgta ccttaacctt ttctgaaaag tttgaaggga gcggctcgcc
     8161 atatttgcga acggcctgtt cacgtgccat ttcactccag tcaatttcac attctcgcat
     8221 cgctttttca gtcgattcac gggaaatgcc tttctgattc aactcctggc gaatacgcgc
     8281 cgggccatag cctttgcggc tacgactggc gataaagcgc atcacgaagc gctcgtcatc
     8341 aagatagtgg tgttcgtggc accaggcgat cacgcgttca taatcgtctg ccgtcgcatc
     8401 aatctcttcc ggcccatttt tgcccatcac cggcgcggag agtttacgcc gtagttcctg
     8461 ctcgctgtga tcgcggacag caagaatacg taccgcacga tcaaggagac gagcataagc
     8521 gggacggcgc gatgtgggtt cactcataaa aaaccttaac aggggtaaat gccaaaaggg
     8581 ccgcataaat gcagcccttg atggtaattt aacgttttgc tgaatggcgg cttcgttttg
     8641 tccgacccac catcacctga tgattaaaaa tcttcgttgg tttctgcaac gccttcgcta
     8701 tcgtcaacgg cgaaatcggg cgtggcattc tgattactca acagtaattc acgcactctt
     8761 ttctcgatct ctttcgctgt tgccgggttc tctttcagcc aggtagtcgc gttcgcttta
     8821 ccctggccaa tcttctcgcc gttgtagctg taccatgcgc ccgctttctc gatcagcttc
     8881 tctttcacgc ccaggtcaac cagttcgcca tagaagttga tgccttcgcc gtagaggatc
     8941 tggaactcgg cctgcttaaa cggcgcggcg attttgtttt tcaccacttt cacacgcgtt
     9001 tcgctaccca cgacattatc gccttctttc accgcgccaa tacgacggat atcaagacga
     9061 acggaggcgt agaatttcag cgcgttaccg ccggtggtgg tttccgggtt accaaacatc
     9121 acgccaattt tcatacggat ctggttgatg aagatcagca gcgtattgga ctgtttcagg
     9181 ttccccgcca gcttacgcat cgcctggctc atcatacgcg ccgcgaggcc catgtgagag
     9241 tcgccgattt cgccttcgat ttccgctttc ggcgttagcg ccgctacgga gtcgaccaca
     9301 atgacgtcca ccgcgcctga acgcgccagc gcgtcacaga tttccagcgc ctgctcgccg
     9361 gtatccggct gagaacagag caggttatcg atatcgacgc ccagcttgcg tgcgtaaaca
     9421 gggtcaagcg cgtgttccgc atcgataaac gcacaggttt taccttcacg ctgcgcagcg
     9481 gcaatcacct gcagcgtcag ggtcgtttta ccggaagatt ccggcccgta aatttcgacg
     9541 atacgcccca tcggcagacc gcccgcaccg agtgcgatat ccagtgaaag cgaaccggtg
     9601 gagatagttt ccacatccat agaacggtct tcacccagac gcatgatgga gcctttacca
     9661 aattgctttt caatttggcc cagtgctgcc gccaacgctt tctgtttgtt ttcgtcgata
     9721 gccattatta ctcctgtcat gcaacttggt attgaaccgg atagtgaatt cgtactgttg
     9781 aagcaattat actgtatgct catacagtat caagtgtttt gtagaaattg ttgccacagg
     9841 gtttgtagcg cgtatgtcgt cgcctgtcga cgcaccgatt cacggtcgcc gctgaagcat
     9901 tcccgacgcg taatcccttc tccactgacg ctggcgaaag caaaccacac cgtaccaacc
     9961 ggcttttctt cactgccgcc atccggcccg gcaatcccgc taatagcgac agcaaaatcg
    10021 gcgcgagcgg ccttcagcgc cccgatcgcc atttcgacca ctacggattc gctgaccgcg
    10081 ccatgctgcg ccagcgtctc ttcacgcacg ccaatcatct gcgctttggc ttcattacta
    10141 taggtgacaa agccgcgttc aaaccaggcg gaacttccgg cgatgtcggt aatggctttc
    10201 gccagccagc cgccggtaca ggactccgct gtcgttacgg tcgccccgcg cgcttttaac
    10261 gccagcccga cctgttcgct aagccgcatc agttcactgt cagtcatcat gacctctgtc
    10321 agttagaaat cctgccgcac aagatagcac tttctcacca gagatgggga cgagctgtcg
    10381 attttacgag tcggattccg aaaaaatgcc agcaggttat ttatgcagaa tgaaagaggt
    10441 agcacatgac taaatagcag tactatgtcg ctaaatttac acgcacggag agaaagcaag
    10501 gatgtcactc aaaaaaacgg aaagcgcaca gcacaaactg aaacaaacct gtcaactacg
    10561 gctgtggtta attgtgggtg gagtatgttc attaggaatg ggagtactga atatattgtc
    10621 gtcaggctat tttgaaccgt atgacggcgg tcaaattatc ttaggcctgg gatgtctggg
    10681 ttatagtctg gcactatcaa aaaagatatc ccacttgcaa gcccaaaaag ccatagtaat
    10741 agcggagggg ggctcccctc cctaagcgta aattagcgca cccgcgccag cgctaccgcc
    10801 tgccccagtt gccaaaccgc catcgcataa tgcgtgctgt ggttatatcg ggtaatggtg
    10861 tagaagttcg gcaggccgta ccagtactgg tatcccgtac cgatatccag acgcagcagg
    10921 ctggcttcct gatgattgcc caacgattgc tgcggcgtta agcctgcggc ggcaagctga
    10981 gagatgctgt attttgtttt gaaaccattc gccaacccag gcgcctgacc actcgccggc
    11041 accgcaacca tatcgccttt cacccaacca tgcgccttga aatagttcgc cacgctgccg
    11101 atggcatcta ccggatccca caagttaatg tgcccatcgc cattgaaatc gaccgcatat
    11161 tctttatagg aagacggcat aaactggccg tagcccatcg cgccggcaaa ggaacctttc
    11221 agattgagcg gatcgtcttg ctcatcgcgc gccatgagca ggaaggtttc cagctcgccg
    11281 gagaaatatt ccgcccggcg cggatagtta aatgacagcg tcgccagcgc gtccagaatc
    11341 cgtgttttcc ccatgatacg tccccagcgg gtttccacgc cgatgatgcc cacaatgatt
    11401 tccggcggta cgccgtatac ctgccaggcg cggttcagcg cgtcttcata ctgattccag
    11461 aacgcgacgc cgttttgcac gttatccggc gtaataaatt gtttgcggta gcgcaaccag
    11521 gcgccatttg gtccggcggg cggctgagtg gtcggcgctt gtctgtccat cagacgcaga
    11581 acgtaatcca gtcttttaga ctgcgagagg atctcttgca gctgctgacg gtcgaaaccg
    11641 tgtttactga ccattttatc aatgaactgc tgcgcattag ggttgttggc gaagtcgccg
    11701 cccatttgca tgacgttatg ctgcggctca agcaggaagc cgccggaagg cgtgcccgtc
    11761 gtcgcttgag tctcggaaga ttttggcgtg ctgctacagg cagcaagcaa tacgcaaagt
    11821 ggaagtaacg ctacataacg acgcttgaac atgagacatc cattaaacaa attcagccag
    11881 ggagaagtat ggtaaagcat ccccccgccg cacaaggaag cggcacaaga gaataaatca
    11941 cctttcccct ctctccagtt tgtatctgct cctccactcc ctcaatcttt caagttaaaa
    12001 tatttttctt
//
LOCUS       DAJVBX010000146        11968 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.146, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000146 DAJVBX010000000
VERSION     DAJVBX010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 11968)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11968)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11968
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.146"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..243)
                     /gene="chbB"
                     /locus_tag="OPV72_003279"
     CDS             complement(<1..243)
                     /gene="chbB"
                     /locus_tag="OPV72_003279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N,N'-diacetylchitobiose transporter subunit
                     IIB"
                     /protein_id="HCR9915495.1"
                     /translation="MEKKHIYLFCSAGMSTSLLVSKMRAQAEKYEVPVIIEAFPETLA
                     GEKGPAADVVLLGPQIAYMLPEIQRLLPGKPVEVIDS"
     gene            complement(544..885)
                     /gene="osmE"
                     /locus_tag="OPV72_003280"
     CDS             complement(544..885)
                     /gene="osmE"
                     /locus_tag="OPV72_003280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmotically-inducible lipoprotein OsmE"
                     /protein_id="HCR9915496.1"
                     /translation="MNKNVAGILSAAAVMTMLAGCTAYDRTKDQFVEPVVKDVKKGMS
                     RAQVAQIAGKPSSEVSMIHARGTCQTYILGQRDGKAETYFVALDDTGHVINSGYQTCA
                     EYDTDPQAPKQ"
     gene            1103..1930
                     /gene="nadE"
                     /locus_tag="OPV72_003281"
     CDS             1103..1930
                     /gene="nadE"
                     /locus_tag="OPV72_003281"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HCR9915497.1"
                     /translation="MTLQQEIIQALGAKPHINPEEEIRRSVDFLKAYLKTYPFLKSLV
                     LGISGGQDSTLAGKLSQMAITELREETGDNALQFIAVRLPYGVQADEQDCQDAIAFIQ
                     PDRVLTVNIKGAVLASEQALREAGIELSDFVRGNEKARERMKAQYSIAGMTHGVVVGT
                     DHAAEAITGFFTKYGDGGTDINPLHRLNKRQGKQLLAALGCPEHLYKKVPTADLEDDR
                     PSLPDEAALGVTYDNIDDYLEGKTLDSAIAKTIEGWYVKTEHKRRLPITVFDDFWKK"
     gene            2051..2932
                     /gene="cho"
                     /locus_tag="OPV72_003282"
     CDS             2051..2932
                     /gene="cho"
                     /locus_tag="OPV72_003282"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011233065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease Cho"
                     /protein_id="HCR9915498.1"
                     /translation="MVRRQSAPRLEFEAAAIYEYPEHLRPFLSEAPALPGVYIFHSES
                     DTLPLYIGKSVNIRSRVLSHLRTPDEAAMLRQARRISWICTAGEMGALLLEARLIKEQ
                     QPLFNKRLRRNRQLCSLQLSEQKIEVVSARSVDFSHEPNLFGLFANRRAALQSLQNLA
                     DEQKLCYGLLGLEPVSRGRACFRFALKRCAGACCGQETPQAHFLRLQASLERLRVVCW
                     PWKGAIALKESRPQMTQFHIINNWLWLGAVPSLDEAATLVRTPAGFDQDGYKILCKPL
                     MSGQYEIIELHTDCRQS"
     gene            complement(3007..3492)
                     /gene="spy"
                     /locus_tag="OPV72_003283"
     CDS             complement(3007..3492)
                     /gene="spy"
                     /locus_tag="OPV72_003283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-independent periplasmic protein-refolding
                     chaperone"
                     /protein_id="HCR9915499.1"
                     /translation="MRKLTALFVASTLAMGAANLAHAAETTTAAPADAKPMMQHKGKF
                     GPHHDMMFKNLNLTDAQKQQIRDIIKAQREQMERPLLEERRAMHDIIASDTFDKAKAE
                     AQITKMEAQRKANMLAHMETQNKIYNVLTPEQKKQYNANFEKRLTERPAQEGKMPAAA
                     E"
     gene            complement(3828..4796)
                     /gene="astE"
                     /locus_tag="OPV72_003284"
     CDS             complement(3828..4796)
                     /gene="astE"
                     /locus_tag="OPV72_003284"
                     /EC_number="3.5.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinylglutamate desuccinylase"
                     /protein_id="HCR9915500.1"
                     /translation="MDNFLALTLSGTTPRVTQGKGAGFRWRWLGHGLLELTPDAPVDR
                     ALILSAGIHGNETAPVEMLDKLLSALYSGSLTLTWRVLVVLGNPQALAAGIRYCHSDM
                     NRMFGGRWQSFAESDETRRARELELSLETFFSSGQARVRWHLDLHTAIRGSHHLRFGV
                     LPQRDRPWEADFLAWLGAAGLEALVFHQAPGGTFTHFSSEHFGALSCTLELGKALPFG
                     QNDLTQFSVTSQALSALLSGVETSTSFSPPLRYRVVSQITRHSDKFALYMDAQTLNFT
                     AFAKGTLLAEEGDKRVTVTHDVEYVLFPNSSVACGLRAGLMLERLP"
     gene            complement(4789..6132)
                     /gene="astB"
                     /locus_tag="OPV72_003285"
     CDS             complement(4789..6132)
                     /gene="astB"
                     /locus_tag="OPV72_003285"
                     /EC_number="3.5.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-succinylarginine dihydrolase"
                     /protein_id="HCR9915501.1"
                     /translation="MTAHEVNFDGLVGLTHHYAGLSFGNEASTRHRFQVSNPRLAVKQ
                     GLLKMKALADAGFPQAVIPPHERPFIPALRQLGFTGSDEQILDKVARQAPRWLSSVSS
                     ASPMWVANAATVCPSADALDGKVHLTVANLNNKFHRALEAPVTEALLRAIFRDESQFS
                     VHSALPQVALLGDEGAANHNRLGGEYGSAGVQLFVYGREEENEIRPARYPARQSREAS
                     EAVARLNQVNPQQVIFAQQNPEVIDQGVFHNDVIAVSNRQVLFCHEAAFARQKVLINQ
                     LRTRVDGFMAIEVPAGEVSVSDAVATYLFNSQLLSRDDGSMLLVLPRECQDHAGVWRY
                     LNKLVAEDNPISAMQVFDLRESMANGGGPACLRLRVVLTEEERRAVNPAVMMNDALFT
                     ALNAWADRYYRDRLTAADLADPLLLREGREALDVLTRLLDLGSVYPFQQTGAADG"
     gene            complement(6129..7607)
                     /gene="astD"
                     /locus_tag="OPV72_003286"
                     /pseudo
     CDS             complement(6129..7607)
                     /gene="astD"
                     /locus_tag="OPV72_003286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460271.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="succinylglutamate-semialdehyde dehydrogenase"
     gene            complement(7604..8638)
                     /gene="astA"
                     /locus_tag="OPV72_003287"
     CDS             complement(7604..8638)
                     /gene="astA"
                     /locus_tag="OPV72_003287"
                     /EC_number="2.3.1.109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine N-succinyltransferase"
                     /protein_id="HCR9915502.1"
                     /translation="MRVIRPVEHADIAALMQLAGKTGGGLTSLLANEATLAARIERAL
                     KTWSGELPKGEQGYVFVLEDSETGEVGGICAIEVAVGLNDPWYNYRVGTLVHASKELN
                     VYNALPTLFLSNDHTGSSELCTLFLDPEWRKEGNGYLLSKSRFMFMAAFRDKFNEKVV
                     AEMRGVIDEHGYSPFWQSLGKRFFSMDFSRADFLCGTGQKAFIAELMPKHPIYTHFLS
                     EEAQAVIGEVHPQTAPARVVLEKEGFRYRHYIDIFDGGPTLECDIDRVRAIRKSRLVE
                     VAEGQPALGDYPACLVANENYHHFRAALVRADPQTSRLVLTAAQLDALKCRAGDHVRL
                     VRLCAEEKTV"
     gene            complement(8629..9855)
                     /locus_tag="OPV72_003288"
     CDS             complement(8629..9855)
                     /locus_tag="OPV72_003288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate aminotransferase family protein"
                     /protein_id="HCR9915503.1"
                     /translation="MSLSVTRENFDEWMVPVYVPAPFIPVRGEGSRLWDQQGKEYIDF
                     AGGIAVNALGHAHPALREALNEQANRFWHTGNGYTNEPALRLAKKLIDATFAERVFFC
                     NSGAEANEAALKLARKYAHDRVGNHKSGIVAFKNAFHGRTLFTVSAGGQPTYSQDFAP
                     LPPDIRHAAYNDLNSASALIDDNTCAVIVEPVQGEGGVIPATNAFLQGLRELCDRHQA
                     LLIFDEVQTGVGRTGELYAYMHYGVTPDILTTAKALGGGFPIGAMLTTQDYASVMTPG
                     THGTTYGGNPLATAVAGKVLDIINTPEMQNGVRQRHDAFIERLNTINVRFGMFSEIRG
                     LGLLLGCVLQTEFAGKAKLIAQEAAKAGVMVLIAGGDVVRFAPALNVSDEEIATGLDR
                     FALACERLQAGGASCG"
     gene            10301..11107
                     /gene="xthA"
                     /locus_tag="OPV72_003289"
     CDS             10301..11107
                     /gene="xthA"
                     /locus_tag="OPV72_003289"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HCR9915504.1"
                     /translation="MKFVSFNINGLRARPHQLEAIVEKHQPDVIGLQETKVHDEMFPL
                     EEVAKLGYNVFYHGQKGHYGVALLTKATPISVRRGFPDDGEEAQRRIIMAEIPSPLGN
                     ITVINGYFPQGESRDHPLKFPAKAQFYQNLQNYLETELKCDNPVLIMGDMNISPTDLD
                     IGIGEENRKRWLRTGKCSFLPEEREWMSRLLKWGLVDTFRQANPQTMDKFSWFDYRSK
                     GFVDNRGLRIDLLLASAPLAERCAETGIDYDIRSMEKPSDHAPVWATFRV"
     gene            11180..11596
                     /locus_tag="OPV72_003290"
     CDS             11180..11596
                     /locus_tag="OPV72_003290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine (deoxy)nucleoside triphosphate
                     diphosphatase"
                     /protein_id="HCR9915505.1"
                     /translation="MIKKLDVVAAIIERDGKILLAQRPVHADQAGLWEFAGGKVEPGE
                     TQPQALIRELREELGIDATPGVYIASHQRDVSGRRIHLHAWHVPAFNGLIRALEHQAL
                     AWCTPEEALEYPLAPADIPLLQAFMALRDARLTDLC"
     gene            complement(11556..11831)
                     /locus_tag="OPV72_003291"
     CDS             complement(11556..11831)
                     /locus_tag="OPV72_003291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnjH family protein"
                     /protein_id="HCR9915506.1"
                     /translation="MRRSLMVAVMAIMPMVGLANQNSRPDIQVNVPPEVFSTRGQSSQ
                     PCIQCCVYQDQNYSEGAVIKVEGVVLQCQRDEKTISTNPLVWRRVKP"
BASE COUNT         2824 a         3401 c         3000 g         2743 t
ORIGIN      
        1 tgaatcaatg acttctaccg gtttaccggg taataaacgc tgaatttcgg ggagcatata
       61 agcaatttgc gggcctaata acacgacgtc cgctgccggg cctttttcac cggccagggt
      121 ttcagggaat gcttcaataa tcaccggcac ttcatatttt tcagcctgag cgcgcatttt
      181 tgataccagt aacgatgttg acatgcccgc agaacaaaac agataaatgt gtttcttttc
      241 cataaaaacc ttcctcatgt gcgattatct gtcaaccaga tacgccgcaa gcctcaacct
      301 gcatccatac tctgggcgac ttgcgtaacc ggatttactt ttttaggtgg ctgaaatgag
      361 tatacgggat cggaccgccg gatggtattt ccttgaccca ctaaattgtc tctcattgac
      421 ctggcgttat gacccccctc acatttcggg caaataattc gcgataataa ataaggttat
      481 ggcaggcaca aaaaaaccgg ctcgcaggcc ggtttccttg aatgttcagg caatgtacag
      541 ttgttactgc ttcggcgcct gtgggtcagt gtcgtactcc gcacaggtct ggtagccgga
      601 gttaatcacg tgcccggtat catccagcgc aacaaagtag gtttccgctt taccatcacg
      661 ttgacccagg atgtaggtct gacaggtacc acgcgcatga atcatgctca cttcagatga
      721 cggtttgccc gcaatctgcg caacttgcgc cctgctcatt ccttttttaa catctttaac
      781 gacaggctca acaaattggt cttttgtacg atcatacgcc gtacagcctg ccagcatagt
      841 cattaccgcc gctgcgctta aaattcctgc tacgttcttg ttcattttcc gtcctcttgt
      901 ttatcagcgt gttatgtaag cctggaatac atcagaacat ttttcaagcc gcgcctcgcg
      961 acaaaaagtc tttcggaaaa ttctctaacg cagcgatatg ttgttttaaa caccgcttag
     1021 cccgccaaac cttgtcgttt cagcggcgaa gggttagctt taacagggta aagattcatt
     1081 ttttaatgtc gaagggggtt aaatgactct gcagcaagag ataatccagg cgcttggcgc
     1141 gaaaccgcat atcaaccctg aagaagaaat tcgccgcagc gtggattttc ttaaagcgta
     1201 cctgaaaacc tatccctttt tgaaatcgct ggtgttaggc atcagcggcg ggcaggattc
     1261 gacgctggcc gggaaactca gccagatggc tatcaccgaa ttgcgggaag agaccggtga
     1321 taatgcgctg cagtttatcg ccgttcgtct gccttatggc gtgcaggccg atgaacagga
     1381 ttgccaggac gccattgctt ttattcagcc ggacagagta ctcaccgtca atattaaagg
     1441 cgccgtcctc gccagcgaac aggcgctgcg cgaagcggga attgagctga gcgattttgt
     1501 tcgcggcaat gaaaaagcgc gtgagcgaat gaaagcgcaa tatagcatcg ccggtatgac
     1561 tcacggcgtc gtggtgggca ccgaccatgc ggcggaagcg ataaccgggt tcttcaccaa
     1621 atatggcgat ggcggtaccg atattaaccc gcttcatcgc cttaacaaac gccagggcaa
     1681 acagcttctc gcagcgctgg gctgtcctga gcatctgtat aaaaaagtcc ccaccgccga
     1741 tttggaagac gaccgccctt cactgcctga tgaagccgcg ctgggcgtaa cgtatgacaa
     1801 tattgacgat tacctggaag gcaaaacgct ggactccgcc atcgctaaaa ctatcgaagg
     1861 ctggtacgta aaaactgaac ataagcgccg tttaccgatt acggtattcg acgacttttg
     1921 gaaaaagtaa gcgtacttct actgttgtgc cggatatcgc tcgtctatcc ggcctcctct
     1981 cttcccagcc tcttttttaa tcacccatcc gctgttatac tggatgaata accagttaac
     2041 ggagatcact gtggtacggc gtcaatcagc cccccgcctt gagtttgaag cagcggccat
     2101 ttacgaatat ccagaacatt tacgtccttt cctcagcgaa gcgccagcct taccgggcgt
     2161 ctatatattt catagcgaaa gcgatacgct gccgctttat atcggtaaaa gcgtaaatat
     2221 tcgcagccgg gtgctctcac atctgcgaac gcctgacgag gccgctatgc tgcgacaggc
     2281 gcggcggata agctggatct gcaccgctgg ggaaatgggc gcgttgctgc tggaggcgcg
     2341 actgatcaaa gaacaacagc cgctgtttaa caagcggtta cgtcgtaatc gccagctttg
     2401 ctctctacag ttgagcgaac aaaagattga ggtcgtttcc gcccgcagcg tcgatttttc
     2461 ccatgagccg aacctgtttg gactcttcgc caaccgtcgg gcagcgctgc aaagcttaca
     2521 gaacctcgcc gatgaacaaa aattgtgtta tggcctgctg gggcttgaac cggtaagccg
     2581 tgggcgcgcc tgttttcgtt tcgcgctgaa gcgctgcgct ggcgcgtgtt gtgggcaaga
     2641 aaccccgcag gcgcattttc ttcgtctgca ggcctcactg gaacggttac gtgtggtttg
     2701 ctggccctgg aaaggcgcta tcgcgttaaa agagagccgc ccacaaatga cccagttcca
     2761 cattatcaac aactggttat ggctgggggc ggtaccctcg ctggatgagg ccgccaccct
     2821 ggtgcgcacc cctgcgggct ttgatcagga tggctataaa attctctgta agccactaat
     2881 gtcaggtcaa tatgagatca ttgaactgca caccgactgt cgccagtcat aaagaaaacc
     2941 gccgatcctg tccacctcaa cgattgtgtt gtcgacaaga ccggcggtct taaattatgc
     3001 ggaaagttat tctgccgcag caggcatttt accttcttgc gccgggcgtt ctgtcagacg
     3061 cttctcaaaa ttagcgttat attgcttttt ctgctccggc gtcagaacgt tataaatttt
     3121 attctgggtt tccatatgcg ccagcatatt ggccttgcgc tgtgcttcca ttttcgtaat
     3181 ttgcgcttcg gctttggctt tatcgaaggt atcgctggca ataatatcat gcatggcgcg
     3241 acgctcttcc agcagcggac gttccatttg ctcgcgctgc gcttttataa tgtcgcgaat
     3301 ttgttgcttc tgcgcgtctg tcaggttcag gtttttaaac atcatatcgt gatgtgggcc
     3361 aaatttacct ttatgctgca tcattggctt cgcatccgct ggcgcggcgg tggtagtctc
     3421 agcggcatga gccagattcg cagcacccat cgccagggta gaggcaacaa atagagcagt
     3481 cagtttacgc atatttccat ccttcctttc agttattttt acggcatatt taaaacagcg
     3541 ccgtgttgtc gtgattaact ttaaccgtct tagcgtcaat tagtcagaac aacggtaaaa
     3601 caatgaaagt ataaaaaaca ctttttcgcc aattgtgaag aaaaaaagaa taaattgcgc
     3661 agagttgaaa gagaaatata caacagcatg atatagcaga aattatgcag aactataacg
     3721 cagcaacgct tattaataaa gcaattctct aggaataatc cgtaatagca tgaaactgtg
     3781 tcccaaatca tccctgtaat cctaacgtga gcttacaggg acatttatca gggcagtctt
     3841 tccagcatta atccagcccg caatccgcag gcgacagagg aattaggaaa gagaacatat
     3901 tcaacgtcat gcgtcaccgt cacgcgctta tccccctcct cggccagcaa cgttcccttc
     3961 gcaaaggcag taaaattcag cgtttgcgca tccatataaa gcgcgaactt gtcgctgtga
     4021 cgcgtgattt gcgacaccac ccgatagcgt agcggcggcg aaaacgaggt tgacgtttcg
     4081 acaccgctca gcaacgccga caacgcctgc gaggttacgc tgaactgcgt cagatcgttt
     4141 tgcccaaacg gcaacgcctt tcccaactcc agcgtacagg aaagcgcgcc gaaatgttca
     4201 gagctaaagt gcgtaaacgt accgccgggc gcctgatgaa ataccaacgc ctccagtcct
     4261 gccgcgccca gccacgccag aaaatccgcc tcccacgggc ggtcgcgctg cggcaatacg
     4321 ccaaaacgca aatgatgcga gccacgaatg gcggtatgca gatccagatg ccagcgtacc
     4381 cgcgcctggc cagatgaaaa gaaggtctcc agacttagct ccagctcacg cgcccgccgc
     4441 gtttcatcgc tttcggcaaa ggactgccaa cgcccgccaa acatacggtt catatcactg
     4501 tgacaatagc gtattcccgc cgccagcgcc tgcggattgc cgagtaccac cagcactcgc
     4561 cacgttaacg tcaagctgcc tgaatacagc gccgacagca gcttatccag catctcgacc
     4621 ggcgcggttt cattaccgtg tatccccgca gaaagaatta acgcgcggtc gaccggcgca
     4681 tcgggcgtga gttcaagcag accatggcct aaccagcgcc agcgaaaacc cgcgcccttc
     4741 ccctgcgtca cccgtggtgt cgtgccgctt agcgtcaacg ccagaaagtt atccatcagc
     4801 cgcccccgtt tgctggaaag gataaaccga ccccaaatcc agcagacgcg ttaacacatc
     4861 cagcgcctcc cggccttctc gcaataataa cggatcggcc agatcggcag cggtcaggcg
     4921 atcgcgataa taacgatccg cccacgcgtt aagggccgta aacagagcgt cattcatcat
     4981 taccgctgga ttcaccgccc gtcgttcttc ttctgttaac accacgcgta atcgcagaca
     5041 ggccgggccg ccgccgttgg ccatactttc tcgcaaatca aacacctgca tcgcgctgat
     5101 ggggttatcc tccgccacca gcttattcag atagcgccag acgccggcat ggtcctgaca
     5161 ttcccgcggc aacactaaca gcattgagcc gtcgtcacgg cttaacaact gactattaaa
     5221 caggtaggtg gccacagcat ctgatacaga aacctctccg gcgggcacct ctatcgccat
     5281 aaaaccgtca acgcgcgtac gcaactgatt aatgagcact ttctgccggg caaacgccgc
     5341 ttcgtgacaa aacaatacct gtcgattcga aacggcgatg acatcattat ggaatacgcc
     5401 ttgatcgatg acctccgggt tttgctgagc gaagataacc tgttgcggat tcacctgatt
     5461 aagacgcgcc acggcctcgc tggcttcgcg gctctggcgc gccggataac gagcgggtcg
     5521 tatttcattc tcctcttcgc gcccatagac aaaaagctgc acgcctgccg aaccatactc
     5581 gccgccaaga cggttatgat tcgccgcgcc ttcatctccc aataatgcga cctgcggtaa
     5641 cgcgctatgc actgaaaact gactttcatc gcgaaatatg gcgcgtagca gcgcttcggt
     5701 aacaggcgcc tcaagagcgc gatgaaattt attgtttaaa ttcgccaccg tcaggtgaac
     5761 tttcccgtcc agcgcgtctg ccgatgggca aaccgtcgcc gcattcgcaa cccacattgg
     5821 cgacgcggaa ctcacgctgg aaagccagcg tggcgcctga cgcgcaacct tatccagaat
     5881 ctgctcatcg ctacccgtga agccgagctg acgtaacgcc ggaataaagg gccgctcatg
     5941 cggcgggatc accgcctggg gaaagccggc atccgccaga gctttcatct ttagcagccc
     6001 ctgctttacc gccagacgag gattcgacac ctgaaaacgg tggcgggtcg atgcctcatt
     6061 gccgaaggat agcccggcat aatggtgcgt aagccccacc agcccgtcaa aattaacttc
     6121 atgcgccgtc ataccgcctc cctgcgagaa aagtcgaggc cagggcttaa tgtcgcaggc
     6181 aacgtcagtt cgggagattc cagactggcc atcggccagg cgcaataatc ggcggcatac
     6241 caggcgctgg gccgatggtt gccagacgcg ccgacaccac caaacggcgc agtactcgct
     6301 gccccggtga gcggtttatt tcagttaacg atccctgccc gcgcctccag caagagttgt
     6361 tcgaactgcg cgcgatccgt cgacaccagc ccacacgaca gaccaaaacg ggtattattc
     6421 gccagacgaa tcgcctcatc gaaatgcgca taacgccaga cgttcagcag cggaccaaac
     6481 acctcttcat ccggcacatc cgcgacgccc gtcagctcaa tgatgccagg cgtcagcaga
     6541 gaggttccct ctttgacctt ccgcggcgcc agtagcgtgc gaccgcctaa tgcctctcgt
     6601 tgacgccagg cctccatcac atgctgtgcc gcctgcgctg aaatcagtcc gccgataaac
     6661 ggctgcgggt cgtcgtccca tctgccgggc tgcagacgtc cggcgacgtc aactagccgc
     6721 gccagaaatg catctccctg cgcgccctgt tttaccagaa ggcgtcgcgc gcaagtacag
     6781 cgctgtccgg cggtaataaa cgccgattgc agcgtcagat gtaccgccgc atccatattt
     6841 gtcgcatcct caataatgag cgggttgttt ccgcccattt caagagccag gattttttcc
     6901 ggctggccgg atagctgacg atgaagctga tatccggtac tggcgctgcc ggtaaacagc
     6961 agtccgtcga gatcgtcgag cgaactcagc gcttgtccgg tctcccggcc gccctgcacc
     7021 agattaagaa cgcctgccgg taaccccgcc cgttcccaga gttttattac cgtttccccg
     7081 gtccatggcg ttagctcgct aggtttgaag atcagcgtat tgcctgccag caacgcgggc
     7141 acaatatggc cattcggtaa atggccggga aagttataag ggccgaatac cgccagcaca
     7201 ccgtgaggac gatggcgcag cgtcgcggca ccatcgacaa gttcgctttt ttgttcgccg
     7261 gttctggcat ggtaagcctt aatcgagatg gcaatcttat tgatcatcgc cgtcacttcc
     7321 gtcgccgcct cccagcgcgg tttaccggtt tcacgcgcga tgacctccgt gagatcggct
     7381 ttatgcgcct ccagcaggac ggaaaatttc tctacgatag cctgccgtgc cgcaaaaggc
     7441 tgtctggccc agcgaggaaa cgccgcgcgc gccgcctgac aggcctcggc gacctgtgcc
     7501 gcatcagcgt cattcccctg ccaaagtatc tcctcgctca ccggattcgt tttgcggcgg
     7561 cgttcgccct gaccggttat ccagtcgccg tttatccata gcgtcatacg gttttctcct
     7621 cagcgcaaag gcgtaccagc cgaacgtggt cgcccgcgcg acatttcagc gcatccaact
     7681 gcgcggcggt aagtacaagt cgtgaagtct gcggatcggc acgcaccagc gcggcccgaa
     7741 agtggtgata gttttcattg gcgaccagac atgcaggata gtcgccaagc gcgggttgcc
     7801 cttccgcgac ttccaccagt cggcttttac gaatagcccg cacgcggtca atatcacact
     7861 ccagcgtcgg cccaccgtcg aagatgtcga tatagtggcg atagcgaaag ccttcctttt
     7921 ccagcaccac gcgggctggc gccgtttgcg ggtggacttc gccaatcacg gcctgtgcct
     7981 cttcagataa gaagtgggta taaataggat gtttgggcat cagctcggcg ataaacgctt
     8041 tttgcccggt accgcataaa aaatccgccc ggctgaaatc catagaaaaa aagcgtttgc
     8101 cgagactttg ccagaaggga gaataaccat gctcgtcaat gacaccgcgc atttccgcca
     8161 ccactttctc attgaattta tcgcgaaacg cggccataaa cataaagcgc gattttgaca
     8221 acaagtagcc gttaccctct ttacgccatt cgggatcgag aaacagcgtg caaagctcac
     8281 tgctgccggt atgatcatta ctcaggaata atgttggcaa cgcgttatat acattcagct
     8341 ctttggaagc atgaaccagc gtaccgacac gatagttata ccaagggtcg ttaaggccga
     8401 ccgcgacctc aatggcgcag atcccgccga cctcacccgt ttcactgtcc tcgagaacaa
     8461 atacatatcc ttgttcgcct tttggcagct cgccggacca ggtttttagc gcgcgttcaa
     8521 tgcgggccgc cagcgtcgct tcatttgcca gtagcgaggt taagccgccg cccgttttgc
     8581 ctgcaagctg catcagcgcg gcgatatccg catgttcgac aggacgaatc acccgcatga
     8641 tgcgcctccc gcctgaaggc gttcgcacgc cagggcaaaa cgatcaagcc cggtagctat
     8701 ctcctcgtcg ctcacattta acgctggcgc aaaacgcacc acgtcgccac cggcgatgag
     8761 caccatcacg cctgcttttg ccgcttcctg ggcgatgagt ttggcttttc cggcaaactc
     8821 cgtctgtagc acacagccaa gcagtagccc cagcccgcga atttcactga acatgccaaa
     8881 acgtacatta atggtattta gacgttcaat aaacgcatcg tggcgctgtc tgacgccgtt
     8941 ttgcatctcc ggcgtattga tgatatccag tacttttccg gcaactgccg tcgccagcgg
     9001 attaccgccg taggtggtgc catgcgtacc tggcgtcatg acgctggcat agtcttgcgt
     9061 agtcagcatc gcgccgatcg ggaagccgcc gcccaacgct ttagcggtcg tcaggatatc
     9121 gggcgtaacg ccataatgca tatatgcata cagttcgccg gtacgtccga cgcccgtctg
     9181 cacctcatca aaaatcagta acgcctgatg ccggtcgcac aattcacgca gcccctgcaa
     9241 aaaagcgttc gtggcgggga tcacgccgcc ctcgccctgc acaggctcta cgattacggc
     9301 gcaggtattg tcatcaatga gcgcgctggc ggagttcaga tcgttatagg ctgcatgacg
     9361 aatatccggc ggcagcggcg caaagtcctg tgaataggtg ggttgaccgc cagcgctgac
     9421 ggtaaagagc gtgcggccat ggaacgcgtt tttaaaggcc acaatgccgc ttttatggtt
     9481 gccaacacga tcgtgggcat atttgcgcgc cagttttaat gcagcttcat ttgcttcagc
     9541 gcctgaatta caaaagaaaa cgcgttcggc gaaggtcgcg tcgatcagtt ttttcgccag
     9601 tcgcagcgcc ggttcattgg tgtaaccgtt cccggtatgc cagaagcgat tcgcctgttc
     9661 atttaacgcc tcgcgcagcg ccggatgcgc atgtcccaat gcgttgaccg caatcccgcc
     9721 agcaaaatca atgtactctt tcccctgctg atcccacagg cgtgagcctt ctccgcgtac
     9781 aggaataaaa ggcgcgggaa catataccgg caccatccat tcatcaaagt tttcgcgcgt
     9841 aactgacaga gacatagcga cctcttttgg taaaaataaa gttatctata tgttaattaa
     9901 tatgggtgtt tgcgctgtaa atgtagattg cagcattcgt gccagccagc gttaacattg
     9961 cataaacaga agtgataaac ggtaaatcaa tgggttacag cgtagcgata ttcactttta
    10021 ctgcatgaaa agtgaatatt tccgcataat cggtggctag aaagaggaaa aagcgaaata
    10081 ttattcagtt gccaaatata attctggaat tgtgatctta tacgaaattt actggaaatt
    10141 accgccccgt tctggcgcat ctgcacgcaa accgtgccat tttcgcgcta tagaaaacac
    10201 catacgcttc cattggccga atctgacgat gagtggcagt cacccggtaa aatttctgct
    10261 accatcccaa cacgattcac cttgcaaagt ggcagtgact atgaaatttg tctcttttaa
    10321 tatcaacggc ctgcgcgccc gtccccatca acttgaagcg attgtcgaaa aacaccagcc
    10381 cgatgtgatc ggtctacagg agacaaaagt ccacgacgaa atgttcccgc tcgaagaggt
    10441 cgcgaagctg ggctataacg ttttctatca tggacaaaaa ggccattacg gcgtcgcgct
    10501 gctaacaaaa gccacgccca tttccgtcag acgcggtttt ccggatgatg gcgaagaggc
    10561 gcaacgccgc attatcatgg cggaaatccc ctcgccgctg ggtaatatca ccgtcattaa
    10621 cggctatttc ccgcaggggg aaagccggga tcatccgttg aagttccccg cgaaagcgca
    10681 gttttatcag aacttgcaaa actatcttga aacggaactc aagtgcgata atccggtatt
    10741 aattatgggc gacatgaata tcagcccgac cgacctggat attggcatcg gcgaagagaa
    10801 ccgcaaacgc tggctgcgta ccggtaaatg ctccttcctg ccggaggagc gtgaatggat
    10861 gtcgcggtta ctgaagtggg gattagtgga cacgttccgt caggcaaatc cgcaaacgat
    10921 ggataaattt tcgtggtttg attaccgttc aaaaggtttc gtggataatc gcggactgcg
    10981 cattgacctc ttgctggcaa gcgctccgct ggcggaacgt tgcgcagaaa ccggtataga
    11041 ctacgacatt cgcagtatgg aaaaaccctc cgaccatgcg ccggtctggg cgacgtttcg
    11101 tgtttgattc cgctatctga ttaaccgtaa ggccgggata gcgcgacgct tcccggcagg
    11161 aataacgacc ttaacgacaa tgataaaaaa actcgatgtt gttgccgcca tcattgaacg
    11221 cgacggcaaa atactgctgg cccagcgccc agttcatgcg gatcaagccg gtttatggga
    11281 gtttgccggc ggtaaagtcg aacccggcga aacccaaccg caggcgctta tccgcgagct
    11341 acgcgaagag ttagggattg acgccacgcc cggcgtctat atcgccagcc atcaacgcga
    11401 cgtgtctggc cgacgaattc atttgcacgc ctggcatgtg cctgcgttta acggtctgat
    11461 acgtgcgctg gaacatcagg ccttagcctg gtgtacgccg gaagaggcgc tggaataccc
    11521 cctcgccccg gcggatattc cgctattgca ggcgtttatg gctttacgcg acgccagact
    11581 aacggatttg tgctgatggt tttttcgtca cgctggcact ggagcacgac gccttccact
    11641 tttattaccg cgccttcgga gtaattctga tcctggtaaa cgcagcactg aatgcagggc
    11701 tgggatgact gaccgcgcgt gctgaaaact tccggcggga cattcacctg aatatcagga
    11761 cgactgtttt ggtttgccag cccgaccatt ggcattatcg ccatcacggc gaccatgagg
    11821 cttcggcgca taggatttcc ttatttttcc aagtatattc tcagtataac ggtaagccgc
    11881 cgtgaaaact ttaatcctct tttgtcatcg cttttagtta tgaccctctc cccgttatga
    11941 atttacttag cagcgtcatt tttttctt
//
LOCUS       DAJVBX010000147        11946 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.147, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000147 DAJVBX010000000
VERSION     DAJVBX010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 11946)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11946)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11946
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.147"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(70..1545)
                     /gene="modF"
                     /locus_tag="OPV72_003292"
     CDS             complement(70..1545)
                     /gene="modF"
                     /locus_tag="OPV72_003292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter ATP-binding protein
                     ModF"
                     /protein_id="HCR9915507.1"
                     /translation="MSSLQISQGTFRLSDTKTLHLDSLTLNAGDSWAFVGANGSGKSA
                     LARALAGELPLLTGERQCQFTRITRLSFEQLQKLVSDEWQRNNTDMLSPGEDDTGRTT
                     AEIIQDDVHHPARYAMLAQQFGISALLNRRFKYLSTGETRKALLCQALMSEPELLILD
                     EPFDGLDVTARQQLAQRLTALNQAGMTLALVLNRFDEIPDFVQFAGVLADCTLAETGT
                     TAELLQRALVAQLAHSERLTDVQLPEPDEPSARHALPDGEPRIVLNDGVVSYNDRPIL
                     HHLSWRVNPGEHWQIVGPNGAGKSTLLSLITGDHPQGYSNDLTLFGRRRGSGETIWDI
                     KKHIGYVSSSLHLDYRVSTTVRNVILSGYFDSIGIYQAVSDRQRKLAQQWLDILGIDK
                     RTADAPFHSLSWGQQRLALIVRALVKHPTVLILDEPLQGLDPLNRQLVRRFVDVLIRQ
                     GETQLLFVSHHAEDAPACITHRLEFVPEGERYKYVSGRCNN"
     gene            complement(1613..2401)
                     /gene="modE"
                     /locus_tag="OPV72_003293"
     CDS             complement(1613..2401)
                     /gene="modE"
                     /locus_tag="OPV72_003293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum-dependent transcriptional regulator"
                     /protein_id="HCR9915508.1"
                     /translation="MQAEILLTLKLQQKLFADPRRISLLKHIALSGSISQGAKDAGIS
                     YKSAWDAINDMNQLSEHMLVERATGGKGGGGAVLTRYGQRLIQLYDLLGQIQQKAFDV
                     LSDDDALPLDSLLAAISRFSLQTSARNQWFGTITARDRDQVQQHVDVLLADGKTRLKV
                     ALTAQSGERLGLEEGKEVLILLKAPWVGITRDAAVARAADNQLSGTISHIERGAEQCE
                     VLMALPDGQTLCATIPTADAATLKEGDDVIAWFNADRVIIATLC"
     gene            2530..2679
                     /locus_tag="OPV72_003294"
     CDS             2530..2679
                     /locus_tag="OPV72_003294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AcrZ family multidrug efflux pump-associated
                     protein"
                     /protein_id="HCR9915509.1"
                     /translation="MLELLKSLVFAVIMVPVVMAIILGLIYGLGEVFNIFSGIGQKDQ
                     SRQNR"
     gene            2846..3619
                     /gene="modA"
                     /locus_tag="OPV72_003295"
     CDS             2846..3619
                     /gene="modA"
                     /locus_tag="OPV72_003295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HCR9915510.1"
                     /translation="MAHSWLRLVAGATLSFVIAGHALADEGKITVFAAASLTNAMQDI
                     AAEYKKEKNVDVVSSFASSSTLARQIEAGAPADLFISADQKWMDYAADKKAVDTTTRE
                     TLLGNSLVVVAPKASEQKPFTIDNKTDWIHLLNGGRLAVGDPQHVPAGIYAKEALQKL
                     GAWQTLEPKLAPGEDVRGALALVERNEAPLGIVYGSDAVASKGVNVVATFPEDSHKKV
                     EYPIAIVEGHKNAAVSAFYDYLKGPQASAIFKRYGFTTK"
     gene            3619..4308
                     /gene="modB"
                     /locus_tag="OPV72_003296"
     CDS             3619..4308
                     /gene="modB"
                     /locus_tag="OPV72_003296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="HCR9915511.1"
                     /translation="MILTDPEWQAVLLSLKVSSLAVLFSLPFGIFFAWLLVRCRFPGK
                     ALLDSVLHLPLVLPPVVVGYLLLVSMGRRGFIGQWLYDWFGLTFAFSWRGAVLAAAVM
                     SFPLMVRAIRLALEGVDIKLEQAARTLGAGRWRVFLTITLPLTLPGIIVGTVLAFARS
                     LGEFGATITFVSNIPGETRTIPSAMYTLIQTPGGESAAARLCVISIVLALISLLISEW
                     LARISRERTGR"
     gene            4311..5369
                     /gene="modC"
                     /locus_tag="OPV72_003297"
     CDS             4311..5369
                     /gene="modC"
                     /locus_tag="OPV72_003297"
                     /EC_number="7.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum ABC transporter ATP-binding protein
                     ModC"
                     /protein_id="HCR9915512.1"
                     /translation="MLELNFSQTLGTHCLTLNETLPASGITAIFGVSGAGKTSLINAI
                     SGLTRPRKGRIVLNGRVLHDAENGICLTPEKRRIGYVFQDARLFPHYKVRGNLRYGMA
                     KSMTGQFDKLVSLLGIEALLDRLPGSLSGGEKQRVAIGRALLTAPELLLLDEPLASLD
                     IPRKRELLPYLQRLAREINIPMLYVSHSLDEILHLADKVMVLEDGQVKAFGPLEEVWG
                     SSVMHPWLPKEQQSSILKVSVLEHHPHYAMTALALGDQHLWVNKLNQPLQSTLRIRIQ
                     ASDVSLVLQPPQQTSIRNVLRAKVANCYDDNGQVEVQLEIGGRTLWARISPWARDELN
                     IKPGLWLYAQVKSVSITA"
     gene            complement(5370..6188)
                     /locus_tag="OPV72_003298"
     CDS             complement(5370..6188)
                     /locus_tag="OPV72_003298"
                     /EC_number="3.1.3.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphatase"
                     /protein_id="HCR9915513.1"
                     /translation="MTARVIALDLDGTLLTPHKTLLPSSLEALSRAKEAGFQLIIVTG
                     RHHVAIHPFYQALALETPAICCNGTYLYDYQAKTVLDADPMPVDKALQLIDLLDEHQI
                     HGLMYVDDAMLYEHPTGHVVRTSRWAQTLPPEQRPTFTQVSSLAQAARDVNAVWKFAL
                     TDEDIPRLQRFGQHVEQALGLECEWSWHDQVDIARKGNSKGKRLTQWIEAQGGSMKNV
                     IAFGDNYNDISMLEAAGTGVAMGNADEAVKARADFVIGDNTTDSIAKFIYTHLL"
     gene            6352..7347
                     /gene="pgl"
                     /locus_tag="OPV72_003299"
     CDS             6352..7347
                     /gene="pgl"
                     /locus_tag="OPV72_003299"
                     /EC_number="3.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconolactonase"
                     /protein_id="HCR9915514.1"
                     /translation="MKQTVYTASPESQQIHVWSLNHEGTLTLVQVVDVPGQVQPMVVS
                     PDKRYLYVGVRPEFRVLAYRIAPDDGALTFAAESALPGSPTHISTDHHGRFVFVGSYN
                     AGNVSVTRLQDGLPVELVDVVEGLDGCHSANITPDNRTLWVPALKQDRICLFTLSDDG
                     HLVAQEPAEVNTVEGAGPRHMVFHPNRQYAYCVNELNSSVDVWQLKNPHGEIECVQTL
                     DMMPADFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLSVEGFQPTEAQ
                     PRGFNIDNSRKYLIAAGQKSHHIAVYEITGTQGLLTEKGRYAVGQGPMWVVVNAY"
     gene            complement(7491..8774)
                     /locus_tag="OPV72_003300"
     CDS             complement(7491..8774)
                     /locus_tag="OPV72_003300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative acyl-CoA thioester hydrolase"
                     /protein_id="HCR9915515.1"
                     /translation="MNTLSVSRLALALAFGVTLSACSSTPPDQIPSDQTAPGTASRPI
                     LSANEAKNFVAARYFASLTPNTAPWSPSPITLPAQPDFVVGPAGTPGVTHTSIQAAID
                     AAMVKRTNKRQYIAIMPGDYQGTVYVPAAPGSLTLYGTGEKPIDVKIGMAIDGEMSVA
                     DWRRAVNPGGKYMPGKPAWYMFDNCQSKHAATIGVMCSAAFWSQNNGLQLQNLTIENT
                     LGDSVDAGNHPAVALRTDGDKVQINKVNILGRQNTFFVTNSGVQNRLQTDRQPRTLVT
                     NSYIEGDVDMVSGRGAVVFDNTNFQVVNSRTQQEAYVFAPATLSNIYYGFLAINSRFN
                     ASGDGVAQLGRSLDVDANTNGQVVIRDSVINEGFNVAKPWADAVISKRPFAGNTGTVD
                     DKDEVQRNLNDTNYNRMWEYNNRGVGSKVVTEPKQ"
     gene            9012..10235
                     /locus_tag="OPV72_003301"
     CDS             9012..10235
                     /locus_tag="OPV72_003301"
                     /EC_number="3.5.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazolonepropionase"
                     /protein_id="HCR9915516.1"
                     /translation="MRQLLPGDTVWRNIRLATMDPQRQAPYGLVDSQALIVREGHICD
                     IVPETQLPVSGDNIHDMQGRLVTPGLIDCHTHLVFAGNRAAEWEQRLNGASYQHISAQ
                     GGGINATVSATRACAEETLYLLARERMMRLASEGVTLLEIKSGYGLELATEEKLLRVA
                     AKLAAENAIDISPTLLAAHATPAEYRDDPDGYITLVCETMIPQLWQKGLFDAVDLFCE
                     SVGFNVAQSERVLQTAKALGIPVKGHVEQLSLLGGAQLVSRYQGLSADHIEYLDEAGV
                     AAMRDGGTVGVLLPGAFYFLRETQRPPVELLRRYQVPVAVASDFNPGTSPFCSLHLAM
                     NMACVQFGLTPEEAWSGVTRHAARALGRQATHGQIRAGYRADFVVWDAEQPVEIVYEP
                     GRNPLYQRVYRGQIS"
     gene            10232..11173
                     /locus_tag="OPV72_003302"
     CDS             10232..11173
                     /locus_tag="OPV72_003302"
                     /EC_number="3.5.3.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formimidoylglutamase"
                     /protein_id="HCR9915517.1"
                     /translation="MTQWYPASPALWQGRDDSIEAPDARRLFQTVTRSEAFFPENWQQ
                     KIALMGFACDEGVKRNSGRPGAAGGPDALRKALANMASHQGHERLVDLGNWVAPTPDL
                     EGAQQALRDAVSRCLRAGMRTLVMGGGHETAFGHGAGVLDAFAQESVGIINLDAHLDL
                     RQTDRATSGTPFRQLAQLCDAQSRAFHYACFGVSRAANTQALWREAQWRNVTVVEDLD
                     CHDALAQMTQFIDKVDKIYLTIDLDVLPVWEMPAVSAPAALGVPLIQVLRLIEPVCRS
                     GKLQAADLVEFNPRFDEDGAAARVAARLGWQIAHWWR"
     gene            11218..11943
                     /locus_tag="OPV72_003303"
     CDS             11218..11943
                     /locus_tag="OPV72_003303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine utilization repressor"
                     /protein_id="HCR9915518.1"
                     /translation="MYSSRSRSAPAPFYETVKQDICKKIAGGVWQPHDRIPSEAELVA
                     QYGFSRMTINRALRELTDEGWLVRLQGVGTFVAEPKGQSALFEVRSIAEEIAARHHQH
                     RCEVLTLERVRANAIQASALNVNESDVIFHSIMVHYENDLPVQIEDRCVNADIAVDYL
                     TQDYRQTTPHAYLSRIAPLTEGEHIVEAVRATAQECAWLTIKEHEPCLLIRRTTWSAS
                     RIVSHARLLFPGSRYRLQGRFIS"
BASE COUNT         2582 a         3147 c         3501 g         2716 t
ORIGIN      
        1 cgttattatt attcttaata aaaggagagt ggttccagaa tggcgcgcgg cgccattctg
       61 ataatacatt taattattgc atcgtccgga aacgtactta taacgttcgc cctctggtac
      121 aaattccagc cggtgggtaa tacaggcagg cgcatcctct gcatgatggg aaacgaacag
      181 cagttgagtc tctccctggc gaattaatac atccacaaaa cggcgtacca gttggcggtt
      241 cagcgggtcc aacccttgca gcggctcatc cagaatcaac actgtcggat gtttaaccag
      301 cgcgcgcacg attagcgcca gccgctgctg tccccaagag agactgtgga agggggcatc
      361 cgccgtacgc ttatcgattc ccagaatatc cagccactgt tgcgccagtt ttcgttgcct
      421 gtctgaaacg gcctggtaaa tgccgataga atcgaaatag ccggagagaa tgacattgcg
      481 taccgtggta ctgacgcggt aatccagatg taaactgctg ctgacgtagc cgatatgttt
      541 tttgatatcc cagattgttt cgccgcttcc tcgccgccgc ccgaacagcg taagatcgtt
      601 gctgtagcct tgcggatgat cgccagtaat aaggctaagc aacgtagact tacccgctcc
      661 gttaggaccg acgatctgcc agtgttcgcc cggattgact cgccagctta ggtggtggag
      721 gatagggcga tcgttatacg agactacgcc atcgttaagt acgatccgtg gttcgccatc
      781 gggtaacgca tggcgggcgg aaggttcgtc cggttcgggt aattgtacgt cggtcagacg
      841 ctcgctgtgc gcgagttgag cgaccaacgc ccgttgcagt aactctgccg tcgttccggt
      901 ctccgccagc gtacagtcgg caagcacgcc ggcaaactgc acgaagtccg ggatctcatc
      961 aaaacggttg agtaccagcg ccagggtcat acccgcctgg ttcaacgccg tcaggcgttg
     1021 tgccagttgt tgacgggcgg tcacgtcaag tccgtcgaac ggttcatcaa ggattaataa
     1081 ctccggctca gacatcagcg cctgacacag cagcgctttt cgcgtctcgc cggtagaaag
     1141 gtatttaaaa cgcctgttga gtaaagcgga aatgccaaac tgctgcgcca gcatcgcata
     1201 gcgggcagga tggtgaacat catcctgaat aatttccgcg gtagtgcgcc cggtatcgtc
     1261 ttcgccagga ctgagcatat cggtgttatt acgttgccac tcatcgctga ccagcttttg
     1321 caattgttca aaggacagac gggtaatgcg ggtaaactga cactggcgct cgcctgttaa
     1381 taatggcagt tcacccgcca gcgcgcgggc gagcgccgac ttcccgctcc cgttagcccc
     1441 aacgaatgcc cagctatcgc ccgcattgag cgtcagcgaa tccagatgaa gtgtttttgt
     1501 atcgctcaga cgaaacgtgc cttgcgaaat ttgcaacgat gacattttgc atcccatttt
     1561 ttgcagcgat gaatgacagg gatacgtctt tcggcaacgg atgtcaatgt gcttagcaca
     1621 acgttgcaat aatcactctg tccgcattaa accaggcaat cacgtcatcg ccttccttta
     1681 acgtggcggc atccgcagtc ggtatcgtgg cgcacagcgt ctggccgtcc ggcagcgcca
     1741 tcaacacttc acactgttcc gcgccgcgct cgatatggct gatcgttccc gacaactgat
     1801 tgtcagctgc gcgcgcaacg gctgcatccc gggtaatgcc aacccacggc gcttttagca
     1861 ggatcagcac ttcttttccc tcctccaggc cgagacgctc gccgctttgc gccgtcagcg
     1921 cgactttgag ccgcgttttg ccgtcggcca gcagcacgtc gacatgctgt tgcacctgat
     1981 cgcgatcgcg ggcggtaatg gtgccgaacc actgatttcg ggcgctggtt tgcagtgaaa
     2041 agcgggagat agcggccagc agactgtcaa gcggcagggc gtcatcgtcg cttaacacat
     2101 cgaacgcttt ttgctgaatt tggcccagca aatcgtaaag ctggatcaga cgctgaccat
     2161 agcgggttaa taccgcgccg ccgccgcctt tgccgcccgt tgcgcgttca accagcatat
     2221 gttcgctaag ctggttcatg tcgtttatcg catcccaggc gctcttatag ctgattcccg
     2281 cgtctttcgc gccctgacta atcgagccgg aaagcgcaat gtgtttcagc agagagatac
     2341 gtcggggatc ggcaaaaagc ttttgctgaa gtttcagggt aagaaggatt tcggcctgca
     2401 taaccagctc ctagtaaaaa gactattgtg actgaaaagc gcgtcagcgc aaagccgacc
     2461 gcacaaaagg ggagtgcttt tctgtgtgat gcggttaaaa tacaaaaagg actatatctg
     2521 gagttgccca tgttagagtt attaaaaagt ctggtattcg ccgtcatcat ggtaccggta
     2581 gtgatggcca tcatcctcgg tctgatttac ggtctgggtg aggtgttcaa cattttttcc
     2641 ggtatcggtc agaaagacca gtccagacag aaccgctgat ttccccaaac gcccgctcag
     2701 tcgggcgttt ttgttactca agatcctgct tttcctgccg atattttctg tgtttaatcg
     2761 ttaatgggta tgaataaccg ctgggaaacc cctgagatta tcgttatatt gttgtttaca
     2821 taacgaaacg cacaaggagt tacagatggc gcattcctgg ttacgcctgg tcgcaggggc
     2881 gacattatct ttcgtcatcg ctggtcatgc gctggcggat gaaggcaaga tcaccgtatt
     2941 cgccgccgcg tcgctaacga acgcgatgca agacattgcg gcagaatata aaaaagagaa
     3001 aaatgtggat gtggtctcct cattcgcctc ctcttcaacg ctggcgcgcc agatagaagc
     3061 gggcgcgccg gcggacctgt tcatctctgc tgatcagaaa tggatggatt acgcagccga
     3121 taaaaaagcg gtggatacca cgacgcgcga aacattgctt ggcaatagcc tggtagtggt
     3181 agcgccgaaa gccagcgagc agaaaccgtt taccatcgac aacaaaacgg actggattca
     3241 tctgctgaac ggcgggcgtc tggcggtggg cgatccgcaa cacgtaccgg cgggaattta
     3301 tgccaaagaa gcgctgcaaa agctgggcgc atggcaaacg cttgaaccga aactggcgcc
     3361 gggcgaggat gtgcgcggtg cgttggcgtt ggtcgaacgt aacgaagcgc ctttaggcat
     3421 tgtatacggt tctgatgcgg tcgccagcaa gggggtcaac gtggtggcga cgttcccgga
     3481 agattcacat aaaaaagtgg aataccccat cgctatcgtg gaggggcata aaaatgcggc
     3541 cgtcagcgcg ttctatgatt acctgaaagg accgcaggcc tcggcaatct ttaaacgtta
     3601 tggatttacg acgaagtaat gatactgacc gatccagaat ggcaggctgt ccttcttagc
     3661 ctgaaagtgt cttccctggc cgtgctgttt agcctgccgt ttgggatctt ttttgcctgg
     3721 ttactggtgc gatgccggtt tccgggcaaa gccttacttg atagtgtcct gcatctgccg
     3781 ctggtgctgc cgccggtggt ggtcggctat ctgctgctgg tgtcgatggg gcgacgcggg
     3841 tttattggcc agtggctgta tgactggttc ggtctcacgt ttgcctttag ctggcgcggc
     3901 gccgtgctgg cggcggcggt gatgtccttc ccgctgatgg tgcgggccat tcggctggcg
     3961 ctggaggggg tggatatcaa gcttgaacag gccgccagaa cgctgggcgc cgggcgctgg
     4021 cgcgtttttc tgactatcac cttaccgctt accctgccgg gtattattgt tggtacggtg
     4081 ctggcgtttg cccgttcgct tggcgaattt ggcgcgacca ttacctttgt ttccaatatt
     4141 ccgggcgaaa cccgcaccat accttccgcc atgtatacct tgatccagac gccgggcggg
     4201 gagagcgcgg cggcgaggct gtgcgtgatt tcgattgtat tagcgctgat ttcgctgttg
     4261 atttctgaat ggctggcgcg gattagccgt gaacggacgg ggcgctaacc atgctggagc
     4321 ttaatttttc ccagacgctg ggaacgcact gtttaaccct caacgaaacg ctgccagcca
     4381 gtgggatcac ggctatcttt ggcgtctccg gcgcgggaaa aacctcgctg attaatgcca
     4441 tcagcggttt gactcgcccg cgaaaaggac gcatcgtgct gaatggccgg gtgttgcatg
     4501 acgcggaaaa cggtatctgt ttaacgccgg aaaagcgccg catcggttat gttttccagg
     4561 atgcgcgcct gttcccccat tacaaagtac gcggcaattt gcgctatggc atggcgaaaa
     4621 gcatgaccgg tcagtttgat aagctggtgt cgctgctggg aattgaagcg ttgcttgatc
     4681 gcctgccggg gagcctgtcc ggcggagaaa aacagcgcgt agcgataggc cgggcattgc
     4741 tcaccgcccc ggagttgctg ctgttggacg aaccgttggc ctcgctggat atcccgcgta
     4801 aacgcgaatt actgccgtac ctgcaacggc tggcgcgaga aatcaatatt cccatgctgt
     4861 atgtcagcca ttctctcgat gaaattctcc acctggcgga taaagtcatg gtgctggagg
     4921 atggacaggt taaagcgttt ggcccgctgg aagaagtctg gggaagcagc gttatgcacc
     4981 cgtggctgcc gaaagagcaa cagagcagta ttctgaaagt cagcgtgctg gagcatcacc
     5041 cgcattatgc catgaccgct ctggcgcttg gcgaccagca cctgtgggta aataaactca
     5101 atcagccgct gcaatccaca ctgcgtattc gtatacaggc gtcggatgtc tcgctggtac
     5161 tacagccgcc gcagcagacc agtatccgca acgtattacg ggcaaaagtg gcgaattgtt
     5221 atgacgataa cgggcaggtg gaagtccagc ttgaaatagg cggcagaacg ctgtgggcgc
     5281 gaataagccc gtgggccagg gatgagctga atatcaagcc tggcctgtgg ctttacgcgc
     5341 aggtgaaaag cgtttctatc accgcctgac tatagcaggt gggtgtatat aaatttggcg
     5401 atgctatcgg tagtgttatc gccgatcaca aagtcagcgc gcgctttcac cgcctcatcg
     5461 gcgttgccca tcgcaacgcc ggtgcctgcc gcctccagca tactgatgtc gttgtagtta
     5521 tcgccgaaag cgatcacatt tttcattgac cctccctgcg cttctatcca ctgggtaagg
     5581 cgcttgcctt tactgttgcc tttgcgcgcg atatccacct gatcgtgcca tgaccattca
     5641 cactccaggc caagcgcctg ttcaacatgc tgaccgaacc gctgtagtct gggaatatct
     5701 tcatcggtaa gcgcaaactt ccacacggca ttcacgtcgc gcgccgcctg cgccaacgaa
     5761 gagacctgtg taaaggtcgg acgttgctcc ggcggcaagg tctgcgccca ccgggaggta
     5821 cgcacgacgt gaccggttgg gtgttcgtaa agcatagcgt catcaacata catcaggccg
     5881 tgaatctgat gctcatccag taaatcaatc aactgcaacg ccttatccac gggcatagga
     5941 tcggcatcca ggacagtttt agcttgataa tcatacaaat aggtgccgtt gcagcaaata
     6001 gcaggtgttt ccagcgccag cgcctgataa aaaggatgaa tagcaacgtg atggcgacca
     6061 gtgacaatga taagttgaaa gcccgcctct ttggcgcgtg atagcgcttc aagcgaggag
     6121 gggagtaagg ttttatgcgg ggttaataat gttccgtcta aatcgagggc aatcacgcgt
     6181 gcagtcataa ttttttccag attaagagta ataattccgt ctgtcggcat ggtacaccgg
     6241 gacggtaagc agacaaaatt ctgcgtctga attcagcatt cgccgtcaaa agcgactacg
     6301 ttaagctgtg tcctgttatt gcagctacat gccatatgca aaggagtatt catgaaacaa
     6361 acagtctata ccgccagccc tgagagtcag caaattcacg tctggagcct gaaccacgaa
     6421 gggacgctga cgctggtgca ggtcgtggat gtgcccggtc aggttcagcc gatggtggtc
     6481 agtccggata aacgctacct ctatgtcggc gtgcgcccgg agtttcgtgt cctggcgtat
     6541 cgtattgcgc cggatgatgg cgcgctgacg tttgccgccg aatccgccct gccgggtagc
     6601 ccgacccata tttctaccga tcatcatggt cgttttgtct ttgtcggatc gtataacgcc
     6661 ggtaatgtca gcgtgacgcg cttacaggat ggcctgccgg ttgagctggt ggatgtggtg
     6721 gaagggctgg acggctgcca ctcggcaaat attacgccgg ataaccgtac cctgtgggtg
     6781 cctgcgctaa aacaggatcg catttgtctg tttacgctaa gcgatgacgg ccatctggtg
     6841 gcccaggagc cggcggaagt aaatacagtt gaaggggcag gcccgcgtca tatggtcttc
     6901 cacccgaatc gacaatatgc gtattgcgtc aatgaactga acagttcggt ggatgtctgg
     6961 cagcttaaaa atccgcatgg cgagatagag tgcgtacaaa ccctggatat gatgcccgcc
     7021 gatttttccg atacccgctg ggcggcggat attcatatta cgccggatgg acggcatctg
     7081 tatgcctgtg accgcaccgc cagtctgatt accgtcttta gtgtctccga agatggcagc
     7141 gtactgagcg ttgaaggctt ccagccgacg gaagcccaac cgcgcggctt taatatcgac
     7201 aacagcagga aatacctgat tgctgcgggt caaaaatcac atcatatcgc ggtctatgaa
     7261 attacgggca ctcaggggtt gctgacggaa aaaggccgtt atgccgtcgg ccaggggcca
     7321 atgtgggttg tggtgaacgc gtactaaagc gctgtgtgcc ggagggcggc gggctggagc
     7381 tcaccagggc aggatgcctg attaatttca ataaacatcg cttgcagtaa aaccacgggc
     7441 cgccacatct gctgcggcgg cccgtttata agcctgaacc ggaacggcga ttactgctta
     7501 ggttccgtca ctactttact gcctacaccg cggttgttgt attcccacat gcggttgtag
     7561 ttcgtgtcgt tcagattacg ctgcacctcg tctttgtcat ccacggttcc cgtatttcca
     7621 gcaaacggac gtttcgagat gaccgcgtcg gcccacggtt tggcaacgtt gaagccctcg
     7681 ttaatcacgc tgtcgcggat cacgacctga ccgttggtgt tggcgtcgac atccagcgag
     7741 cggccaagct gcgcaacgcc atcgccggag gcgttaaagc ggctgttgat cgccaaaaag
     7801 ccatagtaaa tattggacag cgtcgccggg gcgaagacgt aggcttcctg ctgtgtgcgg
     7861 gagttgacga cctggaagtt ggtgttatcg aacaccacgg cgccgcgtcc ggaaaccata
     7921 tccacatcgc cttcaatata gctgttcgtc accagcgtac gcggctggcg atcggtttgc
     7981 agacggttct gcacgccgct gttggtcaca aagaaggtgt tctggcggcc aaggatattg
     8041 accttgttaa tctggacttt gtcgccatcg gtacgcagcg ccaccgccgg atggtttccg
     8101 gcatcgacac tgtcgcccag cgtgttctcg atggtcagat tttgtagctg cagaccgtta
     8161 ttctgcgacc agaacgcggc agaacacatt acaccgatcg tcgcggcgtg tttgctttgg
     8221 cagttatcga acatatacca ggcgggttta ccaggcatat atttcccgcc gggattcact
     8281 gcgcggcgcc agtcagcgac actcatttca ccatcaatcg ccatcccaat ttttacatcg
     8341 atcggttttt caccggtccc gtacagggtc agacttcccg gcgcggcggg aacatacacg
     8401 gtcccctgat agtcgcccgg cataatagca atgtactggc gtttgttcgt gcgtttaacc
     8461 attgccgcat cgatcgcggc ctgaatcgag gtgtgcgtaa cgcctggcgt acctgccggc
     8521 cccaccacaa agtcaggctg tgcgggcagg gtaatcggcg acggcgacca cggggcggta
     8581 ttcggcgtca gggaggcaaa atagcgcgca gcaacgaagt ttttcgcttc atttgccgac
     8641 agaatggggc gcgaggcggt gccaggcgcg gtttgatcgg aagggatctg atcgggtggc
     8701 gtagagctac aggcgctcag cgtcacgcca aaagccagtg ccagcgccag acgggaaacc
     8761 gataatgtat tcacaggttg ctccgggctt gaaaaagtta aatgacatcc attgaagcct
     8821 gcttttttat actaagttga acgaaacggg aaggcgaaaa ggtaaaaagt tccttttcag
     8881 gctggaaaca cctgtagcat cagatagttt tatcacaatt aagcaacaac tttcgcgctt
     8941 tgagttgaca atccggagca gaaagaaaat aaatgtctat acaactcatg acaggcaaga
     9001 gagcgacagg aatgcggcaa cttttaccgg gcgatactgt ctggcgaaac atcaggctgg
     9061 cgacaatgga cccgcagcgg caagccccgt acgggctggt ggatagccag gcgctgattg
     9121 tacgcgaagg gcatatttgc gatatcgtgc cagagacgca gcttcctgtc agtggggaca
     9181 atatccatga tatgcaggga cgactggtaa ccccgggact tatcgattgc cacacgcatc
     9241 tggtgtttgc cggtaaccgc gccgcagagt gggagcagcg gcttaacggc gcgtcatacc
     9301 agcatattag cgctcagggc ggcggcatta acgcgacggt atcagcaacc cgcgcctgtg
     9361 cggaggagac gctctacctg ctggcgcgcg aacgcatgat gcgccttgcc agcgaaggcg
     9421 ttacgctgct ggagattaaa tccggctatg gtctggagct ggcgacagaa gaaaagctgt
     9481 tgcgcgtcgc tgcaaaactt gctgccgaaa acgctatcga cattagcccc acgctattgg
     9541 ccgctcatgc tacgccagcg gagtatcgtg acgacccgga cggctacatc actctggtct
     9601 gcgagacgat gattccgcag ctctggcaaa aagggttatt tgatgcggta gacctctttt
     9661 gcgagagcgt cggctttaat gtggcccaga gtgagcgcgt gttgcagacg gcgaaggcgt
     9721 taggtattcc cgttaaaggc catgttgagc agctttcgct gttgggcggc gcgcagctgg
     9781 tgagtcgtta tcagggttta tcggcggatc atatcgaata tcttgatgaa gcgggcgtcg
     9841 cggcgatgcg tgacggcggt actgtcggcg tgttgttgcc cggcgcgttt tattttctgc
     9901 gcgagacgca gcgcccgccg gttgaactgc tgcgccgcta tcaggtgcct gtcgccgtcg
     9961 ccagcgattt caatcccggc accagcccgt tttgcagttt gcatctggcg atgaatatgg
    10021 cctgcgtaca gtttggtctg acgccggaag aggcatggtc gggcgttacg cgccatgccg
    10081 ctcgcgcgct gggaagacag gcgacgcatg ggcagatcag ggccggctac cgggcggatt
    10141 ttgtggtgtg ggatgctgaa cagccggtag agattgtgta tgagccgggg cgtaaccctt
    10201 tatatcagcg ggtatacaga ggacaaatct catgacgcaa tggtatccgg cttctccggc
    10261 gctctggcag gggcgcgatg acagtataga agcgccggat gcgcggcgtc tgtttcagac
    10321 cgtcacgcgc agcgaggcct ttttccccga aaactggcag caaaagatcg cgttaatggg
    10381 atttgcctgc gacgaggggg taaaacgcaa ttcaggccgt cccggcgcgg caggcggccc
    10441 ggacgcgttg cgtaaagcgc tggcgaatat ggccagccat cagggacatg aacggctggt
    10501 ggatttaggc aattgggttg cgccgacgcc cgatctggaa ggcgcgcagc aggccttgcg
    10561 cgatgcggta agccgctgtc tgcgggccgg gatgcgcacg ctggtaatgg gcggcgggca
    10621 tgaaaccgcg tttggacacg gcgcgggggt gctggacgcg tttgcgcagg aaagcgtagg
    10681 gatcattaat cttgatgcgc atctggatct ccgtcagacc gaccgggcaa catccgggac
    10741 gccgtttcgt caactggcgc agctatgcga cgcgcagagc cgcgcgtttc attatgcttg
    10801 tttcggcgtg agccgtgcgg cgaatacgca ggcgttgtgg cgggaagcgc agtggcggaa
    10861 tgttaccgtg gtggaggatc tggactgcca tgacgcgctg gcgcagatga cgcagtttat
    10921 tgacaaggtg gataaaattt atctgactat cgatctcgac gtattgcctg tctgggaaat
    10981 gccggccgtc tccgctcccg cagcgctggg cgtgccgctg atacaggttc tgcgtttaat
    11041 tgagccggtt tgccgcagcg gaaaattaca ggcggcggat ctggttgaat ttaatccacg
    11101 ctttgatgaa gatggcgcag cggcgcgcgt ggcggcgcgg cttggctggc aaatcgcgca
    11161 ctggtggcgt taatctgtca tccggaaaac attatccgca taaggaaggc ttcacgcatg
    11221 tattcatccc gctcccgttc tgcgcctgcg cctttttacg aaacggtgaa acaggacatc
    11281 tgtaaaaaaa tagccggcgg cgtctggcag ccgcacgatc gcattccgtc ggaagctgaa
    11341 ctggtcgctc agtatggctt tagccgaatg accatcaacc gggcgctgcg tgagctgacg
    11401 gatgaagggt ggctggtgcg tttacagggc gtggggacgt ttgtcgccga accgaaaggc
    11461 cagtccgcac tgtttgaagt ccgcagtatc gccgaggaga ttgccgcccg ccatcatcag
    11521 catcgttgtg aggtgctcac gctggagcgt gtgcgggcaa acgccatcca ggccagcgct
    11581 ctcaacgtca atgagagtga tgtcattttc cattccatca tggtgcatta tgaaaacgat
    11641 ctgccggtac aaattgaaga tcgctgcgtg aatgcggata ttgccgtgga ttacctgacg
    11701 caggattacc gtcagaccac gccgcacgct tatttgtcgc ggatcgcgcc gctaacggaa
    11761 ggggaacata ttgtggaggc ggtgcgcgcc acggcgcaag agtgcgcgtg gttaactatc
    11821 aaagagcatg agccttgtct gctcattcgt cgtacaacct ggtccgcgtc gcggattgtt
    11881 tctcacgccc gcttactttt ccccgggtcg cgctaccggc tacagggacg atttatctcc
    11941 tgagcg
//
LOCUS       DAJVBX010000148        11890 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.148, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000148 DAJVBX010000000
VERSION     DAJVBX010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 11890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11890
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.148"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            159..431
                     /locus_tag="OPV72_003304"
     CDS             159..431
                     /locus_tag="OPV72_003304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000632581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915519.1"
                     /translation="MITPQEARQRTRALVEHYVNECECRDLTDVKHVLTALISMATQA
                     IVATNGKAAALQVLVNTLTHTAENEVPYRMETTAEGGLHITVSRKH"
     gene            441..743
                     /locus_tag="OPV72_003305"
     CDS             441..743
                     /locus_tag="OPV72_003305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000197790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915520.1"
                     /translation="MTRNTELTRTALYRLALQRFGPDAQALKLTEEAAELAASAARNL
                     NGQGSESDLAAELADVEIMTEQLRLQGMDRLIDFHKQKKLERLAARLGVTYTGEII"
     gene            740..1123
                     /locus_tag="OPV72_003306"
     CDS             740..1123
                     /locus_tag="OPV72_003306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001315283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915521.1"
                     /translation="MNRTEQTPQLTPEDAAQRIRVLEDENEYLRKRFEEVDLYFGRNL
                     VVMKAAVIEWRATGDARNGMAWIYNTLCGPGELPPQEEKEAQEYFNRETEVIDRKLAA
                     LYHWFRKYHRTHAAPDQTTTGGTSD"
     gene            1131..1331
                     /locus_tag="OPV72_003307"
     CDS             1131..1331
                     /locus_tag="OPV72_003307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915522.1"
                     /translation="MEIVVWAFLLTGIAVCICAGFALVALLTHVVTQWLWEKLKAAYS
                     LKELSDAVRAWEQQKNTGDTEQ"
     gene            1328..2011
                     /locus_tag="OPV72_003308"
     CDS             1328..2011
                     /locus_tag="OPV72_003308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2786 domain-containing protein"
                     /protein_id="HCR9915523.1"
                     /translation="MTDQDKHIEKLKKLLALAASGNPHEAALALRRARKLMDVHGITH
                     SDIAMSDIDETISHYWPTGSLRPPRYMLGLMNIIREAFGVNSIIHPGTYPGVGFYGNR
                     ERAALAAYTWEVLARQLKKARQQYISAQNKRIKTATRTSRGDQFAEGWVLAVISEIQS
                     FALTDDERELMQQWLEHKYPQTQTTRARKPGRSRNGDASRYAGFREGQNVRLHRPVSG
                     REQQKLEAR"
     gene            2008..2238
                     /locus_tag="OPV72_003309"
     CDS             2008..2238
                     /locus_tag="OPV72_003309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000631816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915524.1"
                     /translation="MITLSGNSRKLKACRISARYLFARAFFKNVRPGITIGVIAGREQ
                     VEKYMSGAWWNKDPVIAARNIHISWGDIQNDD"
     gene            2228..2443
                     /locus_tag="OPV72_003310"
     CDS             2228..2443
                     /locus_tag="OPV72_003310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001297463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915525.1"
                     /translation="MTTESVVCALFWYCFVGWCTAELHRRSGFYSRYSGAGYWISWSV
                     MFLCWPVALPLYVDYIGDAGRRSNNDD"
     gene            2436..2885
                     /locus_tag="OPV72_003311"
     CDS             2436..2885
                     /locus_tag="OPV72_003311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001610542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory protein GemA"
                     /protein_id="HCR9915526.1"
                     /translation="MTKQRLIQLIHIARNELGMDEDTYRQMLQGLTGKASTKGMDTTQ
                     LNCVLESMKRKGFRVRPAGKASSGLPLDNHPQSRKIRALWLEMAAAGIVRDRSENALA
                     RWIKRETGISALRWLNTEQASSVIEKLKKWQRRAAGVKHERPESVSK"
     gene            2857..3246
                     /locus_tag="OPV72_003312"
     CDS             2857..3246
                     /locus_tag="OPV72_003312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001281697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HCR9915527.1"
                     /translation="MSDLNQFRSKGPELLVELAQHTSETVREIIDIEPAIADQIGQAV
                     ANRMMQVWGGQNVYFPMGMVWKVSQRDREIFREFNGRNHHELARKFGVSLQWVYSVVK
                     RVRKEELDRMQGKLFADEPDVDTEKKE"
     gene            complement(3428..4372)
                     /locus_tag="OPV72_003313"
     CDS             complement(3428..4372)
                     /locus_tag="OPV72_003313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HCR9915528.1"
                     /translation="MKLKNTLLASALLSAAAFSVHAATELTPEQAAALKPYDRIVITG
                     RFNAIGDAVSAVSRRADKEGAASFYVVDTSEFGNSGNWRVVADVYKADAPKADAPKNR
                     VINGIVELPKDQAVQLEPYDTVTVQGFYRSQPEVNDAITKAAKQKGAYAFYIVRQIDA
                     NQGGNQRITVFIYKQDAKKRIVQSPDAIPADSEAGRAALAQGGEAAKKVEIPGVATSA
                     SPSAEVGRFFETQSSKGGRYTVTLPDGTKVEELNKATAAMMVPFDSVKFTGNYGNMTE
                     ISYQVAKRAAKKGAKYYHITRQWQERGNNITISADLYK"
     gene            4899..6428
                     /gene="pntA"
                     /locus_tag="OPV72_003314"
     CDS             4899..6428
                     /gene="pntA"
                     /locus_tag="OPV72_003314"
                     /EC_number="1.6.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Re/Si-specific NAD(P)(+) transhydrogenase
                     subunit alpha"
                     /protein_id="HCR9915529.1"
                     /translation="MRIGIPKERLPNETRVAATPKTVEQLLKLGFSVAIESGAGQLAS
                     FDDKAFAQAGADIVDGNAIWQSEIILKVNAPEEEEIALLNPGTTLVSFIWPAQNPGLM
                     EKLAERKVTVMAMDSVPRISRAQSLDALSSMANIAGYRAIVEAAHEFGRFFTGQITAA
                     GKVPPAKVMVIGAGVAGLAAIGAANSLGAIVRAFDTRPEVKEQVQSMGAEFLELDFKE
                     EAGSGDGYAKVMSEAFIKAEMALFAAQAKEVDIIVTTALIPGKPAPKLITRDMVDSMK
                     AGSVIVDLAAQNGGNCEYTVANQVVTTDNGVKVIGYTDLPGRLPTQSSQLYGTNLVNL
                     LKLLCKEKDGNIDVDFDDVVIRGVTVIRDGDITWPAPPIQVSAQPQAAPKAAPAPKEP
                     EKPASPWRKYALMALAIILFGWLADVAPKEFLGHFTVFALACVVGYYVVWNVSHALHT
                     PLMSVTNAISGIIVVGALLQIGQGGWVSFLSFIAVLIASINIFGGFTVTQRMLKMFRK
                     N"
     gene            6439..7827
                     /gene="pntB"
                     /locus_tag="OPV72_003315"
     CDS             6439..7827
                     /gene="pntB"
                     /locus_tag="OPV72_003315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000014033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Re/Si-specific NAD(P)(+) transhydrogenase
                     subunit beta"
                     /protein_id="HCR9915530.1"
                     /translation="MSGGLVTAAYIVAAILFIFSLAGLSKHETSRQGNNFGIAGMAIA
                     LLATIFGPDTGNVAWILVAMIIGGAIGIRMAKKVEMTEMPELVAILHSFVGLAAVLVG
                     FNSYLYHDASLAPVLVNIHLTEVFLGIFIGAVTFTGSIVAFGKLRGKISSKPLMLPNR
                     HKMNLAALVVSFLLLLVFVRTESVGLQVLALLLMTIIALAFGWHLVASIGGADMPVVV
                     SMLNSYSGWAAAAAGFMLSNDLLIVTGALVGSSGAILSYIMCKAMNRSFISVIAGGFG
                     TDGSSTGDDQEAGEHREITAEETAEMLKNSHSVIITPGYGMAVAQAQYPVAEITEKLR
                     ARGINVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINDDFADTDTVLVIGAND
                     TVNPAAQDDPRSPIAGMPVLEVWKAQNVVVFKRSMNTGYAGVQNPLFFKENTQMLFGD
                     AKASVDAILKAL"
     gene            complement(8002..9036)
                     /locus_tag="OPV72_003316"
     CDS             complement(8002..9036)
                     /locus_tag="OPV72_003316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCR9915531.1"
                     /translation="MAKPIITLNGLKIVIMLGMLVVILSGIRFAADIIVPFILALFIA
                     VVLNPVVQRMTRCRIPRVIAVSLLIVIIVMLMVLLLAYLGTSLNELARTLPQYRSSLV
                     IPLQRIEPWLQRAGIGVSVDELAKYIDPNAAMTLVTNLLTQLSNAMSSIFLLLLTVVF
                     MLLEVPQLPEKLQQMMSRPVEGMAAIQRALDSVSHYLVLKTAISIVTGLVAWGMLAAL
                     DVRFAFVWGLLAFALNYIPNIGSVLAALPPIIQVLVFNGFYDALLVLAGYLLINLVFG
                     NILEPRIMGRGLGLSTLVVFLSLIFWGWLLGPVGMLLSVPLTIIVKIALEQTTGGQSI
                     AVLLSDLNKR"
     gene            9453..9815
                     /gene="mdtJ"
                     /locus_tag="OPV72_003317"
     CDS             9453..9815
                     /gene="mdtJ"
                     /locus_tag="OPV72_003317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug/spermidine efflux SMR transporter
                     subunit MdtJ"
                     /protein_id="HCR9915532.1"
                     /translation="MFYWILLALAIATEITGTLSMKWASVGNGNAGFILMLVMITLSY
                     IFLSFAVKKIALGVAYALWEGIGILFITIFSVLLFDEALSTMKIAGLLTLVAGIVLIK
                     SGTRKPGKPVKEATRATI"
     gene            9802..10131
                     /gene="mdtI"
                     /locus_tag="OPV72_003318"
     CDS             9802..10131
                     /gene="mdtI"
                     /locus_tag="OPV72_003318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug/spermidine efflux SMR transporter
                     subunit MdtI"
                     /protein_id="HCR9915533.1"
                     /translation="MQQFEWIHGAWLGLAIMLEIAANVLLKFSDGFRRKCYGILSLAA
                     VLAAFSALSQAVKGIDLSVAYALWGGFGIAATLAAGWVLFGQRLNPKGWVGVILLLAG
                     MVMIKFA"
     gene            complement(10166..10987)
                     /locus_tag="OPV72_003319"
     CDS             complement(10166..10987)
                     /locus_tag="OPV72_003319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HCR9915534.1"
                     /translation="MHKTIAVLLGIVCFLPVMAKAGGAETDATDASDVKTLFFNHDDR
                     VPVADPTQSPWDAIGQLETASGNLCTATLISPHIALTAGHCLLTPPKGKPDKAVALRF
                     VARKGVWRYEIHGIEGRVEPSLGRRLKADGDGWIVPPAAASWDFGLVILRYPPSGITP
                     VPLFTGDKAALTAALKAADRKVTQSGYPEDHLNALYSHQDCVVTGWAQNAVLSHQCDT
                     LPGDSGSPLLLHTDSGWQLIGVQSSAPAAKDRWRADNRAISVTGFRDKLKALAQD"
     gene            complement(11256..11507)
                     /locus_tag="OPV72_003320"
     CDS             complement(11256..11507)
                     /locus_tag="OPV72_003320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001698353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid shock protein"
                     /protein_id="HCR9915535.1"
                     /translation="MKKVLALVVAAAMGLSSAAFAAETATPAKTAAPAKTTQTTQHHK
                     KQHKKTVEQKAQAAKKHQKKDGKKAPAKSTSKTTSQPAA"
BASE COUNT         2808 a         2951 c         3274 g         2857 t
ORIGIN      
        1 ataacagccc tgcgttttca cagcgccatc gccgtgatgt ccggtaaata ccacatccct
       61 gcggtacgcg tcaccctggt ctgcccgtac tgcagccagc atttttcggc agacgtgcct
      121 gtcatggaat tctcccgccc tgacagggag gacgcgcaat gattacccca caggaagcac
      181 gccagcgtac ccgcgccctt gttgaacact atgtcaacga gtgtgaatgc cgcgacctca
      241 ccgatgtgaa gcacgtcctg acggcgctaa tcagcatggc cacgcaggcc attgtggcga
      301 ccaacggaaa ggcggctgca ctgcaggtac tggtgaacac actcacccac acggcagaga
      361 acgaggtgcc gtaccggatg gaaaccactg cagaaggcgg cctgcacatc accgtcagcc
      421 ggaagcactg agggcgcggc atgacacgga acaccgaact cacccgcacc gccctctacc
      481 gtctggccct gcagcgtttc gggccggacg cacaggccct gaaactgaca gaagaggccg
      541 ctgaactggc ggccagtgcc gcccgcaacc tgaacggaca gggcagcgaa agtgacctcg
      601 cggcagagct ggcagacgtg gaaatcatga cagagcagct gcgccttcag ggaatggacc
      661 ggctgattga cttccacaaa cagaaaaaac tggaacgcct tgccgcacgg ctgggcgtca
      721 catacaccgg agaaatcata tgaaccgcac cgaacagacg ccacaactga cgccggaaga
      781 tgctgcacag cgtattcggg tactggaaga cgaaaacgaa tacctgcgca agagatttga
      841 agaggtggac ctgtacttcg ggcgcaatct ggtcgtcatg aaagctgcag tgattgagtg
      901 gcgggccacc ggtgatgcca ggaacggcat ggcgtggatt tacaacaccc tgtgtgggcc
      961 gggcgaactg ccgccgcaag aggagaaaga ggcacaggaa tacttcaaca gggaaactga
     1021 agttatcgac agaaaactgg ctgccctgta ccactggttc aggaaatacc acaggacaca
     1081 cgccgcacct gaccagacca ccacaggagg taccagtgac tgacaccatt atggaaattg
     1141 tggtatgggc tttcctgctt actggtatag ccgtgtgcat ctgcgccgga ttcgccctgg
     1201 ttgccctgct gacccacgtg gtgacgcagt ggttatggga aaagcttaaa gcagcataca
     1261 gcctgaaaga gctgtccgac gctgttcggg catgggaaca gcaaaaaaat accggagata
     1321 ctgaacaatg acagaccagg ataagcacat tgagaaactg aaaaagttgc tggcgctggc
     1381 agcatccggc aacccgcatg aggctgctct ggcactgcgc cgcgcccgta aactgatgga
     1441 tgttcacggc atcacacatt ccgacatcgc catgagtgat attgatgaaa ccatcagtca
     1501 ctactggccg acaggcagcc tccgtccgcc gcgctacatg ctgggcctga tgaacatcat
     1561 ccgcgaggca tttggtgtta actccatcat tcaccccggc acatatccgg gtgtggggtt
     1621 ctacggcaac cgggaacggg ccgcactggc cgcgtacacc tgggaagtgc tggcccgtca
     1681 gctgaaaaag gcgcgtcagc agtatatcag tgcacagaac aaaagaataa aaaccgccac
     1741 ccgcaccagc cgtggagacc agtttgctga aggctgggtg ctggccgtta tcagtgaaat
     1801 acagtccttc gccctgaccg atgacgaacg tgaactgatg cagcagtggc tggaacataa
     1861 atacccgcag acgcaaacca ccagggcgcg taaaccggga agaagtcgca atggcgacgc
     1921 ctcgcgctat gcggggtttc gagaagggca gaacgtcaga ctgcaccgac cggtcagtgg
     1981 gcgggaacag cagaaactgg aggccagatg attacgttat caggtaacag ccggaaatta
     2041 aaagcctgcc gaatatctgc cagatacctt tttgcccgcg ccttttttaa gaacgtcagg
     2101 ccggggatca caattggtgt tattgccgga cgcgaacagg ttgaaaaata catgtcaggt
     2161 gcatggtgga ataaagaccc tgtcattgct gcccgtaata ttcatatcag ttggggggat
     2221 attcagaatg acgactgaat ctgttgtatg tgccctgttc tggtattgtt ttgtcggttg
     2281 gtgtactgct gaactgcacc gccgttcagg gttttattca cgttacagtg gtgccggtta
     2341 ctggattagc tggtcggtga tgttcctgtg ctggcctgtg gcacttcctt tatatgtcga
     2401 ttatatcggt gatgcaggca gaaggagcaa caatgatgac taaacaacgt cttatccagc
     2461 tcattcatat tgcccgtaat gaactgggta tggatgaaga cacctaccgc cagatgttac
     2521 aggggctgac cggtaaagcc tcaaccaaag gaatggatac cacacaacta aactgcgtgc
     2581 tggaatccat gaaaaggaaa ggctttcgcg ttaggcctgc aggaaaagcc agctccggtt
     2641 taccgctgga taaccatccg caatccagga aaatccgtgc gctatggctt gaaatggctg
     2701 ctgccggcat tgttcgtgac cgttcagaaa atgcattagc gcggtggatc aagcgggaaa
     2761 cgggcatcag cgccctgcgc tggctcaata ctgaacaggc aagcagtgtt attgagaaac
     2821 tgaagaagtg gcagcgcaga gctgcgggag taaaacatga gcgacctgaa tcagtttcga
     2881 agtaaagggc cggaactcct ggtggaactg gcacagcata cctctgagac cgttcgcgag
     2941 attattgata ttgagcccgc aattgccgac cagattggtc aggccgtcgc gaaccgcatg
     3001 atgcaggtct ggggcgggca aaacgtttat ttcccgatgg gcatggtatg gaaggtcagt
     3061 cagcgcgacc gggaaatctt cagggagttt aacggacgta accaccatga actggcccgc
     3121 aaatttggtg tttcgcttca gtgggtctac agcgtggtta agcgggtaag aaaagaagaa
     3181 ctggatcgga tgcagggcaa gctatttgct gatgaacccg atgtagatac ggagaaaaaa
     3241 gagtaatatc tgcaatcagg ctggcgcgag ttctgttttt gttcgggccg gtctgatttt
     3301 cacatactgt aaggttattg catattcctc ctggtctctt cccattttga cccagttctt
     3361 cccataaata tctcacttat tccctgtcat ttatctcaag tctaatcacc tgatggcgac
     3421 gcgcgcctta tttatagagg tcggcgctga tggtgatgtt attaccgcgc tcctgccact
     3481 gacgcgtaat atgataatac ttagcgcctt tcttcgccgc gcgtttggcg acctggtagg
     3541 agatttctgt catattgccg tagttgccgg tgaacttaac gctgtcgaaa ggcaccatca
     3601 tcgcagccgt cgctttattc agctcctcaa cttttgtgcc atccggaagt gtgacagtgt
     3661 aacgcccgcc tttggaggat tgcgtttcga agaaacggcc tacttcggcg ctcggcgagg
     3721 ctgacgtggc gacgcctgga atttcgactt tcttcgcagc ttcgccgccc tgagccagcg
     3781 cggcacggcc agcttcagag tctgccggaa tagcgtccgg gctctggacg atgcgttttt
     3841 tcgcatcttg tttatagata aatacagtga tgcgttggtt tccgccctga ttcgcatcta
     3901 tctgacgaac aatatagaaa gcgtatgcgc ctttttgttt cgccgctttc gtaatggcat
     3961 cgttaacttc cggctggcta cggtagaagc cctgaacggt gacggtgtca tacggttcta
     4021 attgtacggc ctggtctttc ggtaattcca cgatgccatt aatgacacga tttttgggcg
     4081 cgtcggcttt cggcgcgtcg gctttataca cgtccgccac aacacgccag ttaccactgt
     4141 tgccgaactc cgaggtgtcg acaacataga aggaggctgc gccttcttta tctgcgcggc
     4201 gggacacggc ggagaccgca tcgccaatag cattaaaacg accggtaata acgatgcggt
     4261 cataaggttt tagtgcagcc gcttgctccg gcgtcagttc tgttgctgca tggacagaaa
     4321 aagcagccgc agaaagcaga gccgacgcca ggagagtgtt cttaagcttc ataaaaataa
     4381 tcctttgcct tgcgcaaacc aggtactggt attgttattg actagaaacg tggctgatta
     4441 ttgcatttaa accatatgga tgtctgcggg atttttcacg catcgtgtca tgtatcctat
     4501 ctttgatgat aacatttact gatatgtcga aaaaaacggc gtccgggcgg ctaagctaat
     4561 gaagcgcata aatttaataa gttaatttaa tgttaatttc ttgatctcgc caggggttta
     4621 atgatgtttt gctgtcaaat ttgagcgaat tatcagccct cgcaggccat tttcaaggca
     4681 ttatggctgc ttagcggctg aatcgttcat gttttgtaaa tttgataaaa aattctgttt
     4741 tttggcgcta gatcacaggc gttattttca gtaggttata gagagtttgt aacggtttta
     4801 ttctgctggg gtaacattta cctcaaacgc gggcaggcgt acgcttctcg cgcttactga
     4861 caaaccatca tcaaaaatac cgatggaagg gaacatttat gcgaattggc ataccaaaag
     4921 agcggttacc caatgaaacc cgtgtcgctg cgacgccgaa aacggtagag cagctactga
     4981 agctggggtt tagcgtcgct atcgaaagcg gggcgggtca actggcaagt tttgacgaca
     5041 aagcgtttgc gcaggctggc gcggatattg tagacggcaa tgctatctgg caatcggaaa
     5101 ttattctcaa ggttaatgcg cctgaagaag aggaaatcgc tttactgaac cccgggacta
     5161 cgctggtcag ttttatctgg cctgcgcaaa atcctgggtt aatggagaaa cttgccgaac
     5221 gtaaggttac ggtgatggcg atggactccg tgccgcgtat ttcccgcgcg cagtcgctcg
     5281 acgcgttaag ctcaatggcg aatatcgcgg gttatcgcgc cattgtagag gccgcgcatg
     5341 aatttgggcg cttctttacc gggcaaatca ctgccgccgg gaaagtgccg ccggcgaagg
     5401 tgatggtgat tggcgcgggc gttgccggtc ttgcggctat cggcgcggca aacagcctgg
     5461 gggcgattgt ccgcgcgttt gacactcgtc ctgaagtcaa agagcaggtc cagagtatgg
     5521 gggctgagtt cctcgaactg gattttaaag aggaagccgg tagcggcgat ggttacgcca
     5581 aagtgatgtc cgaggcgttt atcaaagcgg aaatggcgct ctttgccgcc caggccaaag
     5641 aagtcgatat cattgttacc accgcgttga ttccgggcaa acctgcgccg aagctgatta
     5701 cccgcgatat ggtcgattct atgaaggccg gcagcgtgat tgtcgacctg gccgcgcaga
     5761 acggcggtaa ctgcgaatat accgtcgcca atcaggttgt gacgacggac aatggcgtaa
     5821 aagtgattgg ctacaccgat ctaccggggc gtttgccgac gcagtcatcc cagctttatg
     5881 gcaccaacct ggttaacctg ctgaagctgc tgtgcaaaga gaaagacggc aatattgacg
     5941 tggattttga cgatgtcgtg atccgtggcg tgacggtgat tcgtgacggc gacattacct
     6001 ggcctgcgcc gccaatccag gtttccgcgc agccacaggc cgcgcctaaa gcagcacctg
     6061 cgccaaaaga gccggaaaag cccgcttccc cctggcggaa gtatgcgtta atggcgctgg
     6121 cgatcattct ttttggctgg ctggccgatg tcgcgccaaa agagttcctc ggccatttta
     6181 ccgtgtttgc gctcgcctgc gtggttggtt attacgtggt gtggaacgtg tctcatgcgc
     6241 ttcatacgcc attaatgtcg gtgaccaacg caatttcagg gattattgtt gtcggggcat
     6301 tattgcaaat tggtcagggc ggctgggtca gcttcctgag ctttatcgcg gtgcttatcg
     6361 ccagcattaa tattttcggt ggcttcaccg tgactcagcg tatgctgaaa atgttccgga
     6421 aaaactaagg ggtaacacat gtctggagga ttagttacag ctgcatacat tgttgccgcg
     6481 atcctgttta ttttcagtct tgccgggctt tcaaagcatg aaacgtcccg ccaggggaat
     6541 aacttcggta ttgccgggat ggcgatcgcg ttgctggcga ccattttcgg gccggatacc
     6601 ggcaacgtgg catggattct ggtcgccatg attattggcg gcgcgattgg catccgcatg
     6661 gcgaaaaaag ttgagatgac cgagatgccg gagctggtcg cgattctgca cagtttcgtg
     6721 ggcctggcgg cggtactggt tggctttaac agctatctgt accatgacgc cagtctggcg
     6781 ccggtgctgg tgaatatcca tctgaccgaa gtcttcctcg gtatctttat tggcgcagtc
     6841 actttcactg gatcgatcgt agcgtttggt aaactgcgcg gcaaaatctc ttctaagccg
     6901 ttgatgttgc ctaaccgtca caaaatgaat ctggcggcgc tggttgtttc tttcctgttg
     6961 ctgctggttt ttgttcgtac cgaaagcgtg ggtctacagg ttctggcgct actgctgatg
     7021 accattatcg cgctggcgtt tggttggcat ctggtcgctt ctatcggcgg ggcggacatg
     7081 ccggtggttg tttcaatgct gaactcctat tccggttggg ctgccgcggc ggctggcttc
     7141 atgttgagca acgatttgct gattgtgacc ggcgcgctgg tcggttcgtc aggcgcgatc
     7201 ctgtcttaca ttatgtgtaa agcgatgaac cgctctttca tcagcgttat tgctggtggg
     7261 ttcggtactg acggctcctc aacgggcgac gatcaggaag ctggcgaaca tcgcgaaatt
     7321 acggcggaag agaccgctga gatgctgaaa aactcccact ccgtcattat tacgccgggg
     7381 tacgggatgg cggtagcgca ggcgcagtat ccggtggcgg aaatcaccga aaaactgcgt
     7441 gcgcgcggta tcaacgtgcg tttcggcatt catccggtgg cgggtcgcct gccggggcat
     7501 atgaacgtgc tgttggcgga ggcgaaagtg ccttatgaca tcgtgctgga aatggacgaa
     7561 atcaatgatg atttcgccga taccgatacc gtgctggtga ttggcgcgaa cgatacggtg
     7621 aacccggcgg cgcaagacga tccccgcagc ccgatcgccg gtatgccggt tctcgaagtg
     7681 tggaaagcac agaatgtcgt ggtctttaag cgttccatga atactggtta tgctggtgtg
     7741 cagaacccgc tgttctttaa agagaatacg caaatgctgt ttggcgatgc caaagccagc
     7801 gtggatgcaa ttctgaaagc gctttaatct tttaaacgtg cggcggcctc tttggaggcc
     7861 gtttttatac atttcaccct ataagctgcc tctttgttgg ctgcgctcag aaaccccggt
     7921 cacatcgtta tctatgctcc cggggatttc ttcccttgcc gccgcgatgc atcttgaatg
     7981 attttgtgta tatattgcat tttatctttt gtttaaatcg ctaagcagaa cggcgatact
     8041 ctgcccgccg gtggtctgtt cgagggcgat tttgacaatg atggttaacg gaacggagag
     8101 caacatgccc accggaccta atagccagcc ccagaaaatt aacgacaaaa ataccactaa
     8161 ggttgaaagg cctaaaccac gtcccatgat acgtggctca aggatattgc cgaagaccag
     8221 attaatcagc agatagcccg ccagcaccag cagcgcatca taaaacccgt taaataccag
     8281 cacctgaata atgggcggca gggcagcgag caccgatcca atattaggga tatagttcag
     8341 cgcgaaggcc agtagacccc agacaaaggc gaagcggaca tccagagcgg ccagcattcc
     8401 ccatgcgacc agtcccgtca cgatactgat cgctgttttt agcaccagat aatgtgaaac
     8461 gctatcaagc gcgcgttgaa ttgccgccat accttctacc ggacggctca tcatctgctg
     8521 cagtttttca ggcagttgtg gaacctccag cagcatgaat accacggtca ataacaataa
     8581 aaagatggat gacatggcat tggacagttg ggtgagcagg ttcgttacca gagtcatggc
     8641 ggcgtttgga tcgatatatt tcgccagctc atcaaccgac acgccaatgc ctgctcgctg
     8701 caaccacggt tcaatacgtt gcaacggtat caccaatgag gagcgatact gcggtagggt
     8761 acgggccagt tcatttaatg atgtccccaa ataggccagt agcagtacca ttaacataac
     8821 aataatcaca atgagcaatg atacggcgat aacgcgcgga attcgacatc gggtcatccg
     8881 ttgcacaacg ggattgagaa cgactgcaat aaataacgcc aaaataaagg gaacaatgat
     8941 atctgcggcg aagcggatac cgctcagaat aaccaccagc attcccagca taatgacgat
     9001 ttttagacca ttgagcgtga tgatcggttt tgccatatca gtccctgttt tctatgccga
     9061 cacgaataat aatgtgatgt cggtcgacct gttctggtta aaatcaaaca cttcaggtaa
     9121 agaagtgaaa atattttgag ttaattcctg gcttatgata caaatcaggc gtgttcaact
     9181 accgaggaca attatcatcc gcgatgacga gaagcaacac tgcggataat tgtaatatta
     9241 tggacaatat gttcagcgct tttttctcca cgcaaacgca tcttcactct acctcctttt
     9301 tcctgcttat cggcgagcag cactggcgta acgcacttta gtctctcact tctgcctgag
     9361 ctggcgcaat gcgctgtgct aactgatttt attttttagt ttgctgcgtg cagcagactc
     9421 gaaagagtat attctcatgc aggagaagtg tcatgtttta ctggatttta ttagctctgg
     9481 ctatcgcgac tgaaattacc ggcacgctct caatgaaatg ggctagcgtg ggtaatggca
     9541 atgcgggttt tattttaatg ctggtgatga tcacgctgtc atatatattt ctttcttttg
     9601 cggtaaaaaa gattgccctg ggtgtagcgt atgccttatg ggaagggatc ggcattttat
     9661 ttattaccat ttttagcgtg ctgctatttg atgaagcatt atcaaccatg aagattgccg
     9721 gcttgctgac gctggtcgcc ggcatcgtat tgatcaaatc agggacgcgt aaacccggca
     9781 aaccggtgaa ggaggcgact cgtgcaacaa tttgaatgga tacacggcgc ctggcttggg
     9841 ctggcaataa tgctggaaat cgcggctaac gttctgttga aattttcgga cggctttcgc
     9901 cgtaaatgct atggcatctt atcgcttgcc gctgttctgg ccgccttcag cgcgctttcc
     9961 caggcggtaa aagggataga cctgtcggtg gcgtatgcgc tatggggcgg ttttggtatt
    10021 gccgccacgc tggcggcggg ctgggtgctc ttcggccagc gcttaaatcc caaaggctgg
    10081 gttggcgtga tattgctgct cgccggaatg gtcatgataa aatttgcctg agacgatcgc
    10141 tgccggtcag gcagcgattc ccgcattaat cctgcgccag agctttcagc ttatcgcgaa
    10201 agccggtgac ggatatagcg cggttatcgg cgcgccagcg atctttagcc gcaggggcgg
    10261 agctttgtac gccaatgagc tgccatccgc tatccgtgtg caataataac ggcgagccgc
    10321 tgtcgccagg taacgtgtcg cactggtgtg agagtacggc attctgcgcc cagccggtca
    10381 cgacgcaatc ctgatgggaa tagagcgcat tcagatgatc ttccggataa ccggactgcg
    10441 tgacttttcg gtctgcggct ttcaacgccg cagtgagcgc cgctttatcg ccggtaaata
    10501 aaggcactgg cgtgataccg gaaggtgggt agcgcaatat taccagacca aaatcccagc
    10561 ttgccgcggc aggcggcaca atccagccat cgccatccgc tttcaaacgt cggcccagcg
    10621 acggttcaac gcggccttca atgccgtgga tttcatagcg ccatactcct tttcgcgcca
    10681 caaaacgcag cgcaaccgct ttgtccggtt ttcctttcgg cggcgttagc aggcagtgac
    10741 ctgctgtcag ggcgatatgc ggggagataa gcgttgccgt acacaaatta ccgctggcgg
    10801 tctctagttg cccgatggca tcccacggcg attgggtcgg atcggcgacg ggcactcgat
    10861 cgtcatggtt aaaaaaaagc gttttgacgt cgctggcatc cgtggcgtct gtttcagccc
    10921 ccccggcttt cgccataacc ggtaaaaaac acactatgcc cagtaataca gcaatggttt
    10981 tatgcatatc acactctggt gggtaattat gattattaac aacaaaccct cagtactact
    11041 atagacgtga cggtaagaaa gtgggagtaa aatcagataa ctacactcag gaaagataga
    11101 aatgcgtggc aataacggcg cataaaataa gcacgataag aatgagctca aagcggtagc
    11161 gagacacttt tttgccctcc cggaaggcgg cgctaaacca gaacgattta gcgccgtaaa
    11221 aacgggcgcg ggggcgcgcc gcagcatgtt acgacttacg cagctggttg cgaagttgtt
    11281 tttgacgtag atttggctgg ggcttttttg ccatcttttt tctggtgctt tttagccgcc
    11341 tgcgcttttt gctcaacggt ttttttatgc tgttttttgt ggtgctgggt ggtctgggtt
    11401 gttttggcag gcgctgcggt ttttgcaggc gttgcagtct cagccgcgaa tgctgcggaa
    11461 gagagaccca ttgcagcggc aacaaccaga gctaatactt ttttcatttt gataccctcg
    11521 atttggtttt cattcaaccc cactgcgggg ccggtgaaat gactatatcg ctgttatcaa
    11581 aaggcttccg tgagtgattg gtttcggcat gtaacgctat gtacaatccc ccggtaacgc
    11641 gatgtaagcc cccaccataa taggtagctt tacgttaccg gccgttattt ttggtcgcag
    11701 agtcggtaat atccgccctc cagaataaca ggcacaccgt atatgaatcc gataatctgg
    11761 gtggtattta cgcttctggc gctggatgca atcagagaag tcatgggcgt atcaagcctg
    11821 gcaggtctgt ggtgaacagt gagtcgtggc gtgaaaccag cccggcgata gcgcacgttg
    11881 ctatcgccgg
//
LOCUS       DAJVBX010000149        11854 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.149, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000149 DAJVBX010000000
VERSION     DAJVBX010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 11854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11854
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.149"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            419..1453
                     /gene="rhaT"
                     /locus_tag="OPV72_003321"
     CDS             419..1453
                     /gene="rhaT"
                     /locus_tag="OPV72_003321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose/proton symporter RhaT"
                     /protein_id="HCR9915536.1"
                     /translation="MSNAITMGIFWHLIGAASAACFYAPFKQVKQWSWETMWSVGGIV
                     SWLILPWTISALLLPDFWAYYGQFNLSTLLPVFLFGAMWGIGNINYGLTMRYLGMSMG
                     IGIAIGITLIVGTLMTPIINGNFDVLIHTEGGHMTLLGVFVALIGVGIVTRAGQLKER
                     KMGIKAEEFNLKKGLLLAVMCGIFSAGMSFAMNAAKPMHEAAAALGVDPLYVALPSYV
                     VIMGGGALVNLGFCFIRLAKVQNLSIKADFSLARPLIISNILLSALGGLMWYLQFFFY
                     AWGHARIPAQYDYMSWMLHMSFYVLCGGLVGLVLKEWKNAGRRPVAVLSLGCVVIIIA
                     ANIVGLGMAS"
     gene            complement(1450..2298)
                     /gene="rhaR"
                     /locus_tag="OPV72_003322"
     CDS             complement(1450..2298)
                     /gene="rhaR"
                     /locus_tag="OPV72_003322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator RhaR"
                     /protein_id="HCR9915537.1"
                     /translation="MANQLILLKKDFFTDEQQAVTVADRYPQDVFAEHTHEFCELVMV
                     WRGNGLHVLNERPYRITRGDLFYIRAEDKHSYTSVNDLVLQNIIYCPERLKLNVNWQA
                     MIPGFQGAQWHPHWRLGSMGMNQARQVINQLEHESNGRDPLANEMAELLFGQLVMTLK
                     RHRYATDDLPATSRETLLDKLITALANSLECPFALDAFCQQEQCSERVLRQQFRAQTG
                     MTINQYLRQVRICHAQYLLQHSPLMVSEISMQCGFEDSNYFSVVFTRETGMTPSQWRH
                     LSNQSD"
     gene            complement(2451..3287)
                     /gene="rhaS"
                     /locus_tag="OPV72_003323"
     CDS             complement(2451..3287)
                     /gene="rhaS"
                     /locus_tag="OPV72_003323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator RhaS"
                     /protein_id="HCR9915538.1"
                     /translation="MTVLHSVDFFPSGKAPVAIEPRLPQAAFPEHHHDFHEIVIVEHG
                     TGIHVFNGQPYTISGGTVCFVRDHDRHLYEHTDNLCLTNVLWRSPDAFQFLAGLDQLL
                     PQEQDGYYPSHWRVNQSVLQQVRQLVGLMERAGDGMDAPAVANREILFMQLLVLLRRS
                     SLMEGATNNDAKLNQLMAWLEDHFAEEVCWEAVAEQFSLSLRTLHRQLKQHTGLTPQR
                     YLNRLRLIKARHLLRHSDHSVTEIAYRCGFGDSNHFSTLFRREFNWSPRDIRQGRDAI
                     IQ"
     gene            3575..5044
                     /gene="rhaB"
                     /locus_tag="OPV72_003324"
     CDS             3575..5044
                     /gene="rhaB"
                     /locus_tag="OPV72_003324"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HCR9915539.1"
                     /translation="MTFRHCVAVDLGASSGRVMLARYDSKHRTLTLREIHRFVNCLQK
                     TDGFDTWDIDSLEKDIRLGLKKVCNEGILIDSIGIDTWGVDYVLLDKQGQRVGLPVSY
                     RDNRTTGIMPQALVQIGKSEIYRRSGIQFLPFNTIYQLRALTKQQPELTAQVAHALLM
                     PDYFSYRLTGEMNWEYTNATTTQLVNINTDDWDDTLLAWTGAKKSWFGRPSHPGNVIG
                     DWICPQGNRIPVVAVASHDTASAVIASPLANKHSAYLSSGTWSLMGFESKKPYTTDEA
                     LAANITNEGGAEGRYRVLKNIMGLWLLQRVLKERRITDLPVLIAQTEALPACRFLINP
                     NDDRFINPDDMRAEIQAACRETDQPVPVSDAELARCIFDSLALLYADILHELANLRGE
                     KFTQLHIVGGGCQNALLNQLCANACGIRVMAGPVEASTLGNIGIQLMTLDELNNVDDF
                     RQVVSANYDLTTYIPNPDSEIARHVAQFQPKRQTKELCA"
     gene            5041..6300
                     /locus_tag="OPV72_003325"
     CDS             5041..6300
                     /locus_tag="OPV72_003325"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HCR9915540.1"
                     /translation="MTTQLEQAWELAKQRFAAVGIDVEEALRQLDRLPVSMHCWQGDD
                     VAGFENPEGSLTGGIQSTGNYPGKARNATELRADLEQALRLIPGPKRLNLHAIYLESD
                     TPVARDQIKPEHFKNWVEWAKANRLGLDFNPTCFSHPLSADGFTLSHPDAKIRQFWID
                     HCKASRRVSAYFGEQLGTPSVMNIWIPDGMKDITVDRLAPRQRLLEALDEVISEKFDP
                     AHHIDAVESKLFGIGAESYTVGSNEFYMGYATSRQTALCLDAGHFHPTEVISDKISAA
                     MLYVPRLLLHVSRPVRWDSDHVVLLDDETQAIASEIVRHNLFDRVHIGLDFFDASINR
                     VAAWVIGTRNMKKALLRALLEPTDQLRQLEASGDYTARLAMLEEQKSLPWQAVWEMYC
                     QRHDTPAGSQWLDSVRTYEKEILSKRS"
     gene            6358..7184
                     /gene="rhaD"
                     /locus_tag="OPV72_003326"
                     /pseudo
     CDS             6358..7184
                     /gene="rhaD"
                     /locus_tag="OPV72_003326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462926.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
     gene            7311..8459
                     /gene="fucO"
                     /locus_tag="OPV72_003327"
     CDS             7311..8459
                     /gene="fucO"
                     /locus_tag="OPV72_003327"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HCR9915541.1"
                     /translation="MSFMLALPKISLHGAGAIADMVNLVANKQWGKALIVTDGQLVKL
                     GLLDSLFSALDEHQMSYHLFDEVFPNPTEELVQKGFAAYQSAECDYIIAFGGGSPIDT
                     AKAVKILTANPGPSTAYSGVGKVKNAGVPLVAINTTAGTAAEMTSNAVIIDSARKVKE
                     VIIDPNIIPDIAVDDASVMLEIPASVTAATGMDALTHAVEAYVSVGAHPLTDANALEA
                     IRLINVWLPKAVDDGHNLEAREQMAFGQYLAGMAFNSAGLGLVHALAHQPGATHNLPH
                     GVCNAILLPIVENFNRPNAVARFARIAQAMGVETRGMSDEVASQEAINAIRTLSKRVG
                     IPEGFSKLGVTKEDIEGWLDKALADPCAPCNPRTASRDEVRELYLEAL"
     gene            8456..8770
                     /gene="rhaM"
                     /locus_tag="OPV72_003328"
     CDS             8456..8770
                     /gene="rhaM"
                     /locus_tag="OPV72_003328"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HCR9915542.1"
                     /translation="MIRKAFVMQVNADAHEEYQRRHNPIWPELEAVLKSHGAHHYAIY
                     LDQERNLLFATVEIESEERWNAVASTDVCQRWWKHMRDVMPANPDNSPVSAELKEVFY
                     LQ"
     gene            complement(8859..9407)
                     /locus_tag="OPV72_003329"
     CDS             complement(8859..9407)
                     /locus_tag="OPV72_003329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004855902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCR9915543.1"
                     /translation="MTQPISVIARSLVRERQQTGLSLAEIARRAGIAKSTLSQLEAGN
                     GNPSLETLWSLCVALDIPFARLLEPQVQKTQVIRRGEGTKVVAEQAHYQAILLAACPP
                     GARRDIYLLLTQPGADRISHPHPPGSVEHIIVTQGKALVGLTEAPEELAEGDYICYPG
                     DQAHIFKALEPDTQAILVAEQN"
     gene            9508..10167
                     /locus_tag="OPV72_003330"
     CDS             9508..10167
                     /locus_tag="OPV72_003330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HCR9915544.1"
                     /translation="MKHYFSCLKGDTIKAIFLVCLAVGVVGMSYGSLAMAYGFPLWVP
                     FVLSIFVLAGASEFMFIGIVASGGNPLAAAAAGLLVNARHVPFGVTVRDLVGTRAASF
                     FGCHIMNDESVVFGLSQKTPEQRKAAYWLCGLGVALFWPIGTLIGAGVGKLLPAPETI
                     GLDAVFPAILLALVIPAFKNRTTLIRGCSGAALSLAAVPFVAAGLPVLLSLLGLLARK
                     K"
     gene            10167..10490
                     /locus_tag="OPV72_003331"
                     /pseudo
     CDS             10167..10490
                     /locus_tag="OPV72_003331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462921.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
     gene            complement(10833..>11854)
                     /locus_tag="OPV72_003332"
     CDS             complement(10833..>11854)
                     /locus_tag="OPV72_003332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462920.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF3829 domain-containing protein"
                     /protein_id="HCR9915545.1"
                     /translation="KTEATPAASSQPATPAPSQTPETQSGESPAQPPAAKPETATQPP
                     AAKPETPAQPEVDAEEVYSEKMDVYIDCFNKLQLPVQHSLARYADWVKDFKKGPTGKE
                     SLVYGIYGITESYITNCQKEMKQVAALTPLLEPIDGVAVSYIDSAAALGNTINEMEKY
                     YTQENYKDDGFAKGKALHQTLLKNIEDFKPISEKYHEAIQEINDKRQLTQLKKIEEAE
                     GKTFNYYSLAVMISAKQINKVISADTFDAEAMMKKVAELETMIAQLKEVNTDGRNSSF
                     ISSAADYQLQAKKYIRRIRDNVEYSDFEKKRVQDPATGWMVADSYPASLRSYNEMVDD
                     YNRLR"
BASE COUNT         2724 a         3205 c         3087 g         2838 t
ORIGIN      
        1 tatatttata tttcattgat tcctaacgtt aatttcaata tatttaaatt gtaaatacaa
       61 ataaaacaac taaataatta ctgtataact acccttttat caaacggtaa gtcagactat
      121 tcccattatg tgatctcacg cagcgttttc tttgcattac tgccagctaa gtcgtttcgt
      181 gtcgttatga tgaaggtatt ttagaaaaca aatattaccc actgatttaa ataacatcca
      241 gacggtcacg atgcgctccg acttttttaa aacgtgaagt taatcacttc attaacgtgc
      301 tgattgccag aatacaccca acggcggcaa tcgttataag gttaccaggc tgcgtaattt
      361 ttaaactcat gcaaacggaa ggggtatccc gtccataaaa aataatgagg aacatgtcat
      421 gagtaacgcg attacgatgg gtattttctg gcatctgata ggggcggcca gtgcagcctg
      481 cttctatgcc ccgttcaagc aagtgaaaca gtggtcatgg gaaaccatgt ggtcagtggg
      541 cggcatcgtc tcatggctta ttctgccgtg gacaattagc gctctgttac tgcctgattt
      601 ctgggcctat tatgggcagt ttaacctctc caccctttta ccggtttttc tgttcggcgc
      661 catgtggggc atcggcaata ttaactacgg cctgaccatg cgttatctcg gcatgtcgat
      721 gggtatcggc atcgctatcg gcattacgct tatcgtcggc acgctgatga cgcctatcat
      781 caacggtaac ttcgatgtat taatccatac cgaaggggga cacatgacgc tacttggcgt
      841 ttttgtcgcg ctgatcggcg tcgggattgt gacgcgcgcc ggacagttaa aagaacgcaa
      901 aatgggcatt aaagcggagg agttcaatct gaagaaaggg cttctgctgg cagtgatgtg
      961 cggtattttc tcggcgggga tgtcttttgc catgaacgcc gcgaaaccga tgcatgaagc
     1021 tgctgccgcg cttggcgttg acccgctcta tgtcgcgctg ccgagttacg tggtgattat
     1081 gggcggcggc gcgctggtga acctcggttt ctgttttatc cgcctggcaa aagtgcaaaa
     1141 tctgtcgata aaagccgact tctcgctggc aaggccattg attatcagca atattctgct
     1201 gtccgcgctt ggcggtctga tgtggtattt gcagttcttt ttctatgcct ggggtcacgc
     1261 gcgcattccc gcgcaatatg actacatgag ctggatgctg cacatgagct tctatgtgct
     1321 gtgcgggggg cttgtcggtc tggtgctaaa agagtggaaa aatgctggcc gccgtcccgt
     1381 tgccgtatta agcctcggct gcgtggtaat tattatcgcg gcgaatattg tcggtttagg
     1441 catggccagt taatcgcttt gattactgag atggcgccat tggctcggcg tcatcccggt
     1501 ttcccgcgtg aacaccactg aaaaataatt actatcttca aagccacact gcatcgaaat
     1561 ctcgctaacc atcagcgggc tatgctgaag cagatactgc gcgtggcaaa tacggacctg
     1621 gcgtaaatat tgattaatcg tcatcccggt ttgggcgcga aactgctgcc gcagcacccg
     1681 ctcgctgcat tgttcctgct ggcaaaacgc atccagcgca aagggacact caaggctatt
     1741 agccaaagcg gtaattaatt tatccaacag ggtttctcgg gaggttgccg gaagatcgtc
     1801 ggtcgcgtag cgatgccgtt ttaacgtcat taccagttga ccaaacagca attccgccat
     1861 ctcattcgcc agcggatcgc gtccattact ctcatgttca agctggttaa tgacctgccg
     1921 cgcctgattc attcccatac tgcccagccg ccagtgagga tgccactgcg ctccctgaaa
     1981 gccgggaatc atcgcctgcc agtttacatt gagtttcaaa cgctccgggc agtaaataat
     2041 attttgcagc accagatcgt taacggaagt ataggagtgt ttgtcttcag cacgaatgta
     2101 aaacagatcg ccgcgggtaa ttctgtatgg gcgctcatta agaacgtgta ggccattgcc
     2161 ccgccagacc atcaccagtt cacaaaactc atgcgtatgt tccgcaaaaa catcctgtgg
     2221 atagcgatcg gcaaccgtaa cggcctgctg ctcatcagta aaaaaatctt ttttcaaaag
     2281 gattaactga tttgccaccg cagcacctca tgttgaatgc ttgccggctg gcgctacgct
     2341 tattctgtct accgctcgcc gccgtaggcc aggtaaggcg cagccgccat ccggtattaa
     2401 agggtataat tatcagcata ttggcgacga aaacgttgat agcgttcgcg ttactggatt
     2461 atcgcatcgc gtccctgacg gatatcccgc ggcgaccagt taaattctcg gcgaaacaga
     2521 gtcgaaaagt ggttactgtc gccaaaaccg cagcggtacg cgatttctgt cacgctatga
     2581 tcgctatggc gcaataaatg ccgggctttg atcaaacgca ggcgattaag gtaacgttgc
     2641 ggcgtcagcc cggtatgctg tttaagctga cgatgcagcg tacgtagcga cagcgaaaac
     2701 tgttcagcta ccgcctccca gcagacctcc tccgcaaaat ggtcttccag ccatgccatc
     2761 agttggttga gtttggcgtc gttattggtc gcgccttcca tcaggctact gcggcgtaac
     2821 aacaccagta gttgcataaa caaaatttcg cgattcgcca cggcaggcgc atccatgccg
     2881 tctccggcgc gctccatcag accgaccaac tggcgcacct gctgcaacac actctgattc
     2941 acccgccagt gagaaggata gtaaccatcc tgctcctgcg gcagcaattg atccaacccc
     3001 gccaggaact ggaaggcgtc cggtgaacgc cacagtacat tcgtcaggca taggttgtcg
     3061 gtatgttcat ataaatgccg gtcgtgatcg cgaacaaaac acacggtacc gccgctgatg
     3121 gtatacggct gcccgttgaa tacatgaatg cccgtaccgt gttccacaat cacgatttca
     3181 tgaaaatcat gatgatgttc agggaaagcg gcttgcggca gacgaggttc aatcgccacg
     3241 ggcgctttac ctgatggaaa aaaatccacg ctatgcagta cggtcatggt tgcttcctcc
     3301 tgaattcaac atgtccgaat agtaattaag ggttatcggc ctcaccttaa atttttgacg
     3361 ctaaagcgcg caaacatggt ctttttttca agaaaaggcg ggaaaaagcg ggaaatgcgg
     3421 acgacatcac accggcctat tagtagaaac tgtgaacgct atcacgttca tctttgcctt
     3481 gttgccagcg gctcattttc ctgtcagtaa cgagaaggta ggtctttgag ggctttttta
     3541 gactgtgcgc aatgactcta agaaggacct gattatgact tttcgccatt gtgtcgcggt
     3601 tgatctcggc gcatccagcg ggcgcgtgat gctggcgcgt tacgacagca aacaccgtac
     3661 cctgacgcta cgtgaaattc accgttttgt gaactgccta caaaaaacag acgggtttga
     3721 cacctgggac atcgacagtc tggaaaagga tatccgtctt ggtctgaaga aagtctgcaa
     3781 tgaaggcatt cttatcgaca gcatcggcat cgacacctgg ggcgtcgatt atgtcctgct
     3841 ggataaacaa ggtcagcgtg tcggcctgcc ggtctcctac cgcgataacc gtaccacggg
     3901 catcatgccg caagcgctgg tccagatcgg caaaagcgaa atctatcgcc gcagcgggat
     3961 tcagtttctg ccgtttaaca ccatctatca gctacgcgcg ctgacgaaac aacagcctga
     4021 gttaacggcg caggtcgctc atgcgctgct gatgcctgat tatttcagct accgcctgac
     4081 cggtgaaatg aactgggagt acaccaacgc cacgaccacc cagttggtca atatcaatac
     4141 cgatgactgg gacgataccc tgctggcgtg gaccggcgcg aaaaagagct ggttcggccg
     4201 cccctcgcac cctggcaatg ttatcggcga ctggatttgc ccgcagggca accgtattcc
     4261 ggtggtagcc gtcgccagcc acgataccgc cagcgccgtt attgcctctc cgctggcaaa
     4321 taaacatagc gcttacctgt cttcaggcac ctggtcgttg atgggttttg aaagcaaaaa
     4381 accctacacc actgatgagg cgctggccgc caatatcacc aacgaaggcg gcgcggaagg
     4441 gcgttatcgg gtactgaaaa acattatggg tttgtggctg ctccagcgcg tgctgaaaga
     4501 acggcgcatt accgatctgc ctgtgcttat cgcccaaaca gaagcgctgc cggcctgccg
     4561 tttcctgatt aacccgaatg acgatcgctt tatcaatcct gacgatatgc gcgccgaaat
     4621 ccaagccgcc tgtcgcgaga ccgaccagcc cgttcccgtc agcgatgccg aactggcgcg
     4681 ctgcattttc gacagtctgg cgctgttgta tgccgacatt ctgcacgaac tggcaaatct
     4741 gcgcggcgaa aaatttaccc aactgcatat tgtcggcggc ggatgccaaa acgcgctact
     4801 caaccagttg tgcgccaatg catgtggcat tcgcgtgatg gccgggccgg ttgaagcctc
     4861 cacccttggc aatattggta ttcagcttat gaccctcgac gaattaaaca acgtcgatga
     4921 tttccgtcag gtcgtcagcg ctaactacga cctgacaacc tatatcccta atcctgatag
     4981 tgaaattgcc cgccacgttg cgcagtttca acccaaacga cagacaaagg agctttgcgc
     5041 atgaccactc aactggaaca agcctgggaa ctggcaaaac aacgtttcgc cgcagtaggt
     5101 attgatgtcg aggaggcgct gcgccagctc gatcgcctgc cggtttccat gcactgctgg
     5161 cagggcgacg atgttgccgg attcgagaac ccggaaggtt cgctgacggg cggaattcaa
     5221 tcgaccggca actatccggg caaagcgcgt aacgccaccg aactgcgcgc cgatctggaa
     5281 caggcgctgc gtctgatccc aggccccaaa cgtctgaacc tgcatgcgat ctatctggaa
     5341 tccgatacgc cggttgcccg cgaccaaatc aaaccggagc attttaaaaa ctgggtggag
     5401 tgggcgaaag cgaaccgact ggggctggat ttcaacccca cctgtttttc tcatccactg
     5461 agcgctgacg gttttaccct ctctcatcca gacgcgaaaa ttcgccagtt ctggatcgat
     5521 cactgcaaag ccagccgccg cgtctcggca tactttggtg agcagctcgg tacgccgtcg
     5581 gtgatgaaca tctggattcc ggacggcatg aaagacatta ccgtcgaccg tttagccccg
     5641 cgccagcgcc tgctggaagc gctggatgag gtcattagcg agaaattcga cccggcgcac
     5701 cacatcgacg ccgttgagag caaactgttt ggcatcggcg cggaaagcta caccgtcggc
     5761 tccaatgagt tctacatggg ctacgccacc agccgtcaga ccgcgctgtg tctggatgcg
     5821 ggccacttcc atcccactga agtgatttcc gacaaaattt ccgccgccat gctctatgtg
     5881 ccacggctgc tgctgcacgt cagccgcccg gtacgctggg atagcgacca cgtggtgctc
     5941 ttggacgatg aaacccaggc aattgccagc gagatcgtcc gtcataacct gttcgaccgt
     6001 gtgcatatcg gcctggattt cttcgacgcc tctatcaacc gtgtcgccgc gtgggttatc
     6061 ggtacccgca acatgaaaaa agcgctactg cgcgctctgc tggaacccac agatcaactg
     6121 cgtcagcttg aggccagcgg cgattacacc gcgcgtctgg cgatgctgga agagcaaaaa
     6181 tctctgccgt ggcaggccgt ctgggaaatg tattgccagc gtcacgacac gccggctggc
     6241 agccagtggc tggacagcgt tcgcacctac gaaaaagaga tcctgagcaa acgtagctga
     6301 cagcgacacc tgatctgtag gccggataac cttcgggcaa taaatgggaa cacgaatatg
     6361 caaaatatta ccgattcctg gtttgtccag ggcatgatta aagccacgtc tgatgcgtgg
     6421 ctgaaagggt gggacgagcg taatggtggc aacctgacgc tgcgcctgga tgaagcagac
     6481 atcgcgccat ttagcgccga tttccacgaa aaaccacgct atatcacgct aagtcaactc
     6541 atgccgctgc tggcgaatac accgtttatc gttaccggct ccggcaaatt cttccgcaac
     6601 gttcagctcg atccggcagc caatttaggc gtggtcaaaa tcgacagcga cggcgctggc
     6661 taccacattc tgtggggctt aacccacgac gcggtaccca cctctgaact cccggcgcac
     6721 ttcctctccc actgcgaacg catcaaagcc acccacggca aagaccgcgt cattatgcat
     6781 tgccatgcga ctaacctgat cgccctcacc tacgtactgg aaaacaacac tgcgctgatc
     6841 acccgcaaac tgtgggaagg cagcaccgaa tgcctggtgg tattcccgga cggtgtcggc
     6901 attctgccgt ggatggtgcc aggcccgatg aaatcggcca agccaccgcg caagaaatgc
     6961 agaaacattc gctggtactg tggccgttcc acggcgtgtt cggaagcgga cctacgctga
     7021 atgaaacctt cggtttgata gataccgcag agaaatccgc tgaggtatta gtcaaaatct
     7081 attcgatggg cggtatgaag cagaccatca cgcgcgaaga actggtcgca ctcggcaaac
     7141 gatttggcgt gacaccgctg gccagcgccg tagagctgta ctgatacctc ccaactcaac
     7201 gccggatgcg gctttgcctt atccggccta caggtcggtg cgcattttac cgtaggcccg
     7261 ataagcgtag cgccatcggg caacagggaa tttttttaag gagaatagtg atgagcttta
     7321 tgttggcact gccaaaaatt agcctgcatg gcgctggagc gattgccgat atggtgaacc
     7381 tcgtggcgaa taagcaatgg ggcaaagcgc tgatcgttac cgatggtcaa ctggtaaagc
     7441 tgggcctgct ggatagcctg tttagcgcac tggatgaaca tcaaatgtct taccacctgt
     7501 ttgatgaggt gttcccaaac ccgacagaag agctggtgca gaaaggtttt gcggcgtatc
     7561 agagcgcaga atgtgactac attatcgcct tcggcggcgg cagcccgatc gataccgcaa
     7621 aagcggtgaa aattctgacc gccaacccag gtccatctac cgcctactcc ggcgtcggca
     7681 aagtgaaaaa cgccggcgta ccgctggtag cgattaacac tacggcaggt accgcggcag
     7741 agatgaccag caacgcggtg attatcgact ctgcccgtaa ggtcaaagag gtgatcatcg
     7801 acccgaatat catcccggat attgccgtgg atgacgccag cgtcatgctg gaaatcccgg
     7861 cgtctgtgac cgccgcaacc ggcatggatg ccctgaccca tgcggtggaa gcctatgtct
     7921 ccgttggcgc gcatccgctc accgacgcta acgcgctgga agcgattcgc ttaatcaatg
     7981 tgtggctacc gaaagcggtt gacgatggtc ataacctcga agcccgtgag caaatggcat
     8041 tcggccagta cctggcgggt atggcgttca acagcgccgg tttggggctg gttcacgcgc
     8101 tggcgcacca gccgggcgca acccacaacc tgccgcacgg cgtctgcaac gctatcctgc
     8161 tgccaattgt cgagaacttt aaccgtccga acgccgtcgc gcgttttgcc cgcatcgcac
     8221 aggcgatggg cgtggagacg cgcggtatgt ctgacgaagt cgcaagtcag gaagcgatta
     8281 acgctatccg tacgctgagc aaacgcgtcg gcattccaga aggtttcagc aagctgggcg
     8341 tcacaaaaga agatatcgaa ggctggctgg ataaagccct cgccgacccg tgcgcgccgt
     8401 gtaacccgcg caccgccagc cgcgatgaag ttcgcgagct gtacctggag gcgttatgat
     8461 ccgcaaagcc tttgtgatgc aggtaaatgc cgacgcgcac gaggagtatc agcgtcgtca
     8521 taacccaatc tggccggagc tggaagccgt attaaaatct cacggcgcgc atcactacgc
     8581 gatttatctc gatcaggagc gcaatctgct gttcgccacc gttgagattg aatccgagga
     8641 gcgctggaac gccgttgcca gcaccgacgt ttgccagcgt tggtggaaac atatgcgtga
     8701 cgttatgccc gcgaatccgg ataacagccc ggtcagcgca gagctaaaag aggtgttcta
     8761 tctgcagtaa gtcgtgtgcc cgatggcgca agcttaccgg gcctacggtt ttattttttg
     8821 tcggccggat aaggcggtta cgccgccatc cggcaatttc aattctgctc cgctaccagg
     8881 atagcctgag tatccggttc cagcgcttta aagatatgcg cctggtcgcc gggataacaa
     8941 atgtaatcgc cctccgccag ctcttccggc gcctcggtta agccgacgag ggcttttccc
     9001 tgcgtaacaa taatatgttc caccgacccc ggcggatgcg gatgagagat ccggtcggcc
     9061 cccggctgcg tcaacagcag atagatatca cgccgcgcgc cgggcggaca cgccgccagt
     9121 aatatcgcct gataatgcgc ctgctccgcc acgactttgg tgccttctcc gcggcgaatc
     9181 acctgcgttt tttgtacctg cggctccagc agcctggcaa agggaatgtc gagcgcgacg
     9241 catagcgacc atagcgtctc caggctgggg ttgccgttcc ctgcttccag ttgtgaaagc
     9301 gtagatttag cgatgcctgc gcgccgcgca atctccgcca gcgacagtcc ggtttgctgg
     9361 cgttcgcgta ccaggcttct ggcaatgacg ctaataggtt gtgtcataaa gcatccaacg
     9421 ttcactataa cgaacgaaat gttcgtcttg taaagcaaat ctgttccgtt cattataatg
     9481 aaaattcgtt cgatatgact aaagaagatg aaacactatt tttcctgtct caagggagac
     9541 acgataaaag cgatattttt agtgtgcctg gccgtgggcg tcgtcggcat gtcctatggc
     9601 tcactggcga tggcctacgg tttcccactg tgggtgccgt ttgtcctctc tatttttgtg
     9661 ctggcgggcg cgtccgaatt tatgtttatc ggcattgttg ccagcggcgg caatccgtta
     9721 gcggcggcgg cggcaggact actggtgaat gcgcgccacg tgccgtttgg cgtaacggtg
     9781 cgcgatttgg ttggcacccg cgccgccagc tttttcggct gccatatcat gaatgatgag
     9841 agcgtggtgt tcggcctgtc gcaaaaaaca cccgaacaac gtaaagccgc ctactggcta
     9901 tgcggtctgg gcgtcgccct attctggccg attggcacac tgattggcgc aggtgtcggc
     9961 aaactgctcc cggccccaga aaccatcggt ctggacgccg tattcccggc aatcttactg
    10021 gcgctggtga tcccggcgtt taaaaaccgc accacattga ttcgtggttg cagcggcgcc
    10081 gcgctgtcgc ttgccgccgt tccctttgtg gctgccggat tgccggtgtt gctttcgctg
    10141 cttggcctac tggcgaggaa aaaataatgg gcaatatgac gctatttatt atcggtattg
    10201 ctcttttatc tacgggaacc tatttgatgc gcctcggcgg cgcgaaactt ggcagccgtc
    10261 tggcgctgtc tgagcgttca caggcgctgc tctcggatgc ggcaacggtg ctgctattct
    10321 ccgtcgcgct ggcgaccacc ttttacgaag gcgaacattt tgccggaatg gcgcgcgttc
    10381 ttggggttgg cttcgccgta tttttagcct gacgtaaaat gccgcttatt gtggtgatta
    10441 tcgccgctgc agtggtgacc gcgttattac gaatggcggg tattaattaa cgtcttacag
    10501 aacagttgga cgtgacaccc tataagtgat gaaggctggg ccgccctatg ctgaagtggc
    10561 tcagaatttt cgcatcaggg ggataaatgt tttccatatg aatgccgatt ctcaattaca
    10621 ctatcagagt aacttcaaca tcttgtgata gcttcagatt actggttttc ctaatagctc
    10681 tccttagtta aggtttacgt cagctatttt tacggatatt gcctgacgaa atgcatgaac
    10741 gaaaaaagcg cctgatcggc gctctttatt ggtgttatag cgtaacttta taggcgctta
    10801 cgccagcctg cacgcagtta atgtgccgtc actcaacgca ggcggttata atcatccacc
    10861 atctcgttat aacttctcaa cgacgccgga taagaatccg caaccatcca tcctgttgca
    10921 gggtcctgca cccgtttctt ttcaaaatca gaatactcaa cattgtctct gatgcgacga
    10981 atatattttt tagcttgtag ctgataatca gccgcagagc tgatgaaaga agaattacgg
    11041 ccatcagtat tcacttcttt caattgcgca atcattgttt ccagttccgc gacttttttc
    11101 atcatcgctt cggcatcaaa ggtatcggca gaaataacct tgttgatctg ctttgccgaa
    11161 atcatgacag ccagagaata atagttaaat gttttacctt ccgcttcttc tattttcttc
    11221 aactgtgtca attgccgctt gtcatttatt tcctgaatag cctcatgata tttttccgag
    11281 ataggtttaa aatcctcgat attcttcagt aatgtctgat gcagcgcctt acctttagca
    11341 aaaccatcat ctttatagtt ttcctgggta taatattttt ccatttcgtt aatggtatta
    11401 cccagcgcgg cggcgctatc aatatagcta acggcaacgc catcaatagg ctcaagcaat
    11461 ggcgttaagg cggccacctg tttcatctct ttctggcaat tcgttatgta agactccgta
    11521 ataccataaa tgccataaac caggctctct ttccctgtcg gacctttttt aaagtctttc
    11581 acccaatccg cgtaacgcgc cagactgtgc tgaacgggca attgaagttt attaaaacaa
    11641 tcgatataga catccatttt ttcactataa acttcttcag cgtcaacctc cggctgagct
    11701 ggcgtttctg gcttcgccgc cgggggctga gttgctgttt ctggcttcgc tgctgggggc
    11761 tgcgctggac tttcgccaga ttgcgtttcc ggcgtctgag aaggcgctgg cgtcgcaggc
    11821 tgactgctgg cggccggcgt cgcctcggtt ttaa
//
LOCUS       DAJVBX010000150        11850 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.150, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000150 DAJVBX010000000
VERSION     DAJVBX010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 11850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11850
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.150"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..1811)
                     /gene="glmS"
                     /locus_tag="OPV72_003333"
     CDS             complement(<1..1811)
                     /gene="glmS"
                     /locus_tag="OPV72_003333"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HCR9915546.1"
                     /translation="MCGIVGAIAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAEGHMT
                     RLRRLGKVQMLAQAAEEHPLHGGTGIAHTRWATHGEPSEANAHPHVSEHIVVVHNGII
                     ENHEPLREALKARGYTFVSETDTEVIAHLVNWELKQGGTLRDAILRAIPQLRGAYGTV
                     IMDTRHPDTLLAARSGSPLVIGLGMGENFIASDQLALLPVTRRFIFLEEGDIAEITRR
                     SVNIFDNTGAEVKRQDIESNLQYDAGDKGIYRHYMQKEIYEQPNAIKNTLTGRISHGQ
                     VDLSELGPNADDLLSKVEHIQILACGTSYNSGMVSRYWFESLAGIPCDVEIASEFRYR
                     KSAVRRNSLMITLSQSGETADTLAGLRLSKELGYLGSLAICNVPGSSLVRESDLALMT
                     NAGTEIGVASTKAFTTQLTVLLMLVAKLSRLKGLDASIEHDIVHGLQALPSRIEQMLS
                     QDKRIELLAEDFSDKHHALFLGRGDQYPIALEGALKLKEISYIHAEAYAAGELKHGPL
                     ALIDADMPVIVVAPNNELLEKLKSNIEEVRARGGQLYVFSDQDAGFVSSDNMHIIEMP
                     HVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPRNLA"
     gene            complement(2000..3370)
                     /gene="glmU"
                     /locus_tag="OPV72_003334"
     CDS             complement(2000..3370)
                     /gene="glmU"
                     /locus_tag="OPV72_003334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HCR9915547.1"
                     /translation="MLNSAMSVVILAAGKGTRMYSDIPKVLHTLAGKPMVQHVIDAAT
                     KLGAAQVHLVYGHGGELLKQTLKDDKLNWVLQAEQLGTGHAMQQAAPFFSDDEDILML
                     YGDVPLISVETLQRLRDAKPQGGIGLLTVKLDDPSGYGRITRENGKVTGIVEHKDATD
                     EQRQIQEINTGILIANGADLKRWLSKLTNNNAQGEYYITDIIALAYQEGREIAAVHPA
                     RISETDGVNNRLQLSRLERIYQAEQAEKLLLSGVMLRDPARFDLRGTLYCGMDVEIDA
                     NVIIEGYVTLGHRVKIGAGCIIKNSVIGDDCEISPYSVVEDAHLEAACTIGPFARLRP
                     GAELLAGAHVGNFVEMKKARLGKGSKAGHLTYLGDAEIGDNVNIGAGTITCNYDGANK
                     FKTVIGDDVFVGSDTQLVAPVTVGKGATIAAGTTVTRNVADNELVLSRVPQVHKQGWQ
                     RPVKKK"
     gene            complement(3690..4388)
                     /locus_tag="OPV72_003335"
     CDS             complement(3690..4388)
                     /locus_tag="OPV72_003335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HCR9915548.1"
                     /translation="MSFQPSFAGPQPDSRIDRTTFIRRAYLHLAVAIVGFIVLSAAWS
                     FIGGGEYALDVLLAGGRYSWLVVLGAFMLVGMLATRLADNAGTNQTQLIGLGIYVLAE
                     SLIFAPLLTVAAYINPSSIGAAAITPLLLVGGLTFTAFSIKKDFSFLRSFLTMAGFIA
                     FGAIIASVICGFSLGVWFSALMVLLCAGFILYDTSNIIHHYPTDRPAGAALHLFASIA
                     TMFWYILRIFMSRN"
     gene            complement(4617..5036)
                     /gene="atpC"
                     /locus_tag="OPV72_003336"
     CDS             complement(4617..5036)
                     /gene="atpC"
                     /locus_tag="OPV72_003336"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001251972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HCR9915549.1"
                     /translation="MAMTYHLDVVSAEQQMFSGLVEKIQVTGSEGELGIYPGHAPLLT
                     AIKPGMIRIVKQHGHEEFIYLSGGILEVQPGSVTVLADTAIRGQDLDEARALEAKRKA
                     EEHIKSSHGDVDYAQASAELAKAIAKLRVIELTKKAM"
     gene            complement(5057..6439)
                     /gene="atpD"
                     /locus_tag="OPV72_003337"
     CDS             complement(5057..6439)
                     /gene="atpD"
                     /locus_tag="OPV72_003337"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017800291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HCR9915550.1"
                     /translation="MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNEKLVLEVQ
                     QQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEI
                     GEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMCPFAKGGKVGLFGGAGVGKTVNM
                     MELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRL
                     RVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEM
                     GVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPA
                     VDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVA
                     RARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSI
                     DEAVEKAKKL"
     gene            complement(6466..7329)
                     /gene="atpG"
                     /locus_tag="OPV72_003338"
     CDS             complement(6466..7329)
                     /gene="atpG"
                     /locus_tag="OPV72_003338"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020882764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HCR9915551.1"
                     /translation="MAGAKEIRSKIASVQNTQKITKAMEMVAASKMRKSQDRMAASRP
                     YAETMRKVIGHLANGNLEYKHPYLEERDVKRVGYLVVSTDCGLCGGLNINLFKKLLAD
                     MKAWSDKGVQCELAMIGSKGVSFFNSVGGNVVAQVTGMGDNPSLSELIGPVKVMLQAY
                     DEGRLDKLYIVSNKFINTMSQVPTITQLLPLPASEDDDLKRTAWDYLYEPDPKALLDT
                     LLRRYVESQVYQGVVENLASEQAARMVAMKAATDNGGSLIKELQLVYNKARQASITQE
                     LTEIVSGAAAV"
     gene            complement(7380..8921)
                     /gene="atpA"
                     /locus_tag="OPV72_003339"
     CDS             complement(7380..8921)
                     /gene="atpA"
                     /locus_tag="OPV72_003339"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HCR9915552.1"
                     /translation="MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGL
                     ADCMQGEMISLPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRG
                     LLGRVVNTLGAPIDGKGPVDNDGFSAVEAIAPGVIDRQSVDQPVQTGYKAVDSMIPIG
                     RGQRELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGAL
                     ANTIVVVATASESAALQYLAPYAGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLL
                     LRRPPGREAFPGDVFYLHSRLLERAARVNADYVEAFTKGEVKGKTGSLTALPIIETQA
                     GDVSAFVPTNVISITDGQIFLESNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGG
                     IRTALAQYRELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFA
                     AERGYLADVELAKIGSFEAALLAYVDRDHAPLMQEINQSGGYNDEIEGKLKGILDSFK
                     ATQSW"
     gene            complement(8934..9467)
                     /gene="atpH"
                     /locus_tag="OPV72_003340"
     CDS             complement(8934..9467)
                     /gene="atpH"
                     /locus_tag="OPV72_003340"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015966593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HCR9915553.1"
                     /translation="MSEFVTVARPYAKAAFDFAVEHQSVERWQDMLAFAAEVTKNEQM
                     AELLSGALAPETLAESFIAVCGEQLDENGQNLIRVMAENNRLNALPDVLEQFIHLRAA
                     SEATSEVEVTSATALSEEQLSKISAAMEKRLSRKVKLNCKIDKSVMAGVIIRAGDMVI
                     DGSVRGRLERLADVLQS"
     gene            complement(9482..9952)
                     /gene="atpF"
                     /locus_tag="OPV72_003341"
     CDS             complement(9482..9952)
                     /gene="atpF"
                     /locus_tag="OPV72_003341"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HCR9915554.1"
                     /translation="MNLNATILGQAIAFILFVWFCMKYVWPPLMAAIEKRQKEIADGL
                     ASAERAHKDLDLAKASATDQLKKAKAEAQVIIEQANKRRAQILDEAKTEAEQERTKIV
                     AQAQAEIEAERKRAREELRKQVAILAVAGAEKIIERSVDEAANSDIVDKLVAEL"
     gene            complement(10012..10251)
                     /gene="atpE"
                     /locus_tag="OPV72_003342"
     CDS             complement(10012..10251)
                     /gene="atpE"
                     /locus_tag="OPV72_003342"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HCR9915555.1"
                     /translation="MENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPD
                     LIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA"
     gene            complement(10298..11113)
                     /gene="atpB"
                     /locus_tag="OPV72_003343"
     CDS             complement(10298..11113)
                     /gene="atpB"
                     /locus_tag="OPV72_003343"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HCR9915556.1"
                     /translation="MASENMTPQEYIGHHLNNLQLDLRTFSLVDPQNPPATFWTLNID
                     SMFFSVVLGLLFLVMFRSVAKKATSGVPGKFQTAIELIVGFVHGSVKDMYHGKSKLIA
                     PLALTIFVWVFLMNLMDLLPIDLLPYIAEHWLGLPATRVVPSADVNITLSMALGVFIL
                     ILFYSIKMKGIGGFAKELTLQPFNHWAFIPVNLILEGVSLLSKPVSLGLRLFGNMYAG
                     ELIFILIAGLLPWWSQWILNVPWAIFHILIITLQAFIFMVLTIVYLSMASEEH"
     gene            complement(11122..11502)
                     /gene="atpI"
                     /locus_tag="OPV72_003344"
     CDS             complement(11122..11502)
                     /gene="atpI"
                     /locus_tag="OPV72_003344"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit I"
                     /protein_id="HCR9915557.1"
                     /translation="MPVSLVSRNVARKLLFIQFLAVIASGLLFCLKDPFWGISAVCGG
                     LAVALPNMLFMIFAWRHQAHTPAKGRVSWTFAFGEAFKVLAMLVLLVVALAVLKAVFL
                     PLIVTWVLVLVVQILAPAVINNKG"
BASE COUNT         2883 a         3305 c         2915 g         2747 t
ORIGIN      
        1 ttcgccaagt tacgcggctg gtcaacgtcg gtgcctttaa tcagcgccac gtgatacgcc
       61 agcagttgca gcggaacggt gtagaagata ggcgcaatga cctcttccac atgcggcatc
      121 tcaatgatgt gcatgttgtc gctgctcaca aaacccgcat cctgatcgga gaagacgtac
      181 aactgaccgc cacgcgcgcg aacttcttcg atgttggatt tcagtttctc cagcagttcg
      241 ttgttcggcg ccaccacaat caccggcata tcggcgtcaa tcagcgccaa cggcccgtgt
      301 ttcagctcgc ctgcagcata ggcttccgcg tgaatgtaag agatctcttt cagcttcagc
      361 gcgccttcga gcgcaatcgg atattgatcg ccacgaccga ggaataacgc gtgatgcttg
      421 tcagagaaat cttctgcaag cagctcgatg cgtttgtcct gcgacagcat ctgctcaata
      481 cggctcggca gcgcctgtag gccatgcacg atatcatgct caatggacgc atccagacct
      541 ttcaggcgag acagtttcgc caccagcatc aacagcacgg ttaactgggt ggtgaaggct
      601 ttggtagatg ctacgccaat ttccgtaccc gcgttggtca tcagcgccag atcggattca
      661 cgcaccagcg aagagcccgg cacgttacaa atggccagag agcccaaata tcccagctct
      721 ttcgacagac gcaggccagc cagggtatct gccgtttcgc cagactggga gagcgtgatc
      781 atcaggctgt tacggcgcac ggcagatttg cgatagcgga attcagaggc gatttcaacg
      841 tcgcacggaa tacctgccag cgattcaaac cagtaacggg aaaccatacc ggagttgtaa
      901 gacgtaccgc aggcgaggat ctgaatatgc tcaaccttcg acaacagatc atcggcgttc
      961 ggtcccagct cgcttaaatc cacctgaccg tggctgatgc gcccggtaag ggtgtttttg
     1021 atcgcgttcg gctgttcgta gatctctttc tgcatgtagt ggcggtaaat acctttatcg
     1081 cccgcgtcat attgcagatt ggattcgata tcctgacgtt ttacttccgc gccggtgtta
     1141 tcgaagatat ttaccgaacg gcgagtgatt tcagcgatat cgccctcttc aaggaagata
     1201 aagcgacgag tcactggcaa cagcgccagc tggtcagaag cgataaagtt ttcgcccata
     1261 cccaggccaa tcaccagcgg gctacctgaa cgggcagcca gcagcgtatc cggatggcgg
     1321 gtatccatga tcaccgtgcc atatgcgcca cgcagttgcg ggatcgcacg caaaatcgcg
     1381 tctcgcagag taccaccttg tttcagttcc cagtttacca ggtgtgcaat cacttcggtg
     1441 tcggtttcag aaacgaaggt atagccacgc gcttttaacg cttcacgcag cggttcatgg
     1501 ttttcgatga tgccgttatg caccaccaca atgtgttcag aaacatgcgg atgcgcgtta
     1561 gcttctgaag gttcaccgtg cgtcgcccag cgagtgtgag caataccggt gccgccatgc
     1621 agcgggtgtt cttccgctgc ctgagccagc atctggactt taccgaggcg acgcaggcgg
     1681 gtcatatgac cttctgcatc caccacggcc agaccggcag agtcgtaacc acggtattcc
     1741 agacgacgta aaccttcgag aaggatttca gctacatcac gctgcgcgat agcgccaaca
     1801 attccacaca tagttttatt tcctgattat ggcattacgc catgcgttgt cgctgacctg
     1861 tatgcccgtc gttgcgggcg ccccgagcct tgtagagagt ggggttattt ttataagtac
     1921 tgctcatgga gcggaggatt attttatcct ctcatctccg gtctgccgga tggcgctgac
     1981 gcttatccgg cctacaaaat cactttttct tcaccggacg ctgccagcct tgcttatgca
     2041 cctgcggcac gcggcttaat accagttcat tgtcggctac attacgggtg acggtagtcc
     2101 ctgcggcgat ggtggcccct ttaccaacag taaccggcgc caccagttgg gtatcggagc
     2161 cgacaaacac atcgtcgcca ataaccgttt tgaatttgtt cgcgccatca tagttacagg
     2221 tgatggtccc cgcgccaata ttcacgttgt cgccaatttc cgcatcgccc aggtaggtca
     2281 gatggccggc tttagaacct ttacccagac gcgctttttt catttcaaca aaattgccga
     2341 cgtgagcgcc cgctaacagc tcagcgccgg gacgcaggcg agcaaacggg ccgatggtgc
     2401 aggccgcttc cagatgcgca tcttccacca cgctgtatgg gctaatttcg cagtcatcgc
     2461 caataacgct gtttttaata atgcagcccg cgccgatctt cacgcggtga ccgagcgtta
     2521 cataaccttc gatgataacg ttagcgtcaa tttcgacatc cattccacaa taaagggtgc
     2581 cgcggagatc aaaacgtgcc ggatcgcgca acataacgcc ggataacagc agtttctccg
     2641 cctgttcggc ctggtaaata cgctccagac gagaaagctg tagacggtta ttcacgccgt
     2701 ccgtttcgct gatgcgagcc ggatgcaccg cggcgatttc ccgtccttcc tgataagcca
     2761 gcgcgatgat atctgtgatg taatattcac cctgcgcatt attgttagtc agcttagaca
     2821 accagcgttt caggtccgcg ccgttggcga tcagaatacc agtgttaatt tcctggatct
     2881 gacgctgttc atcagtggcg tctttatgtt caacgatgcc ggtcacttta ccgttttcac
     2941 gcgtaatacg gccatagccg ctcggatcgt ccagcttcac ggttaataac ccaataccac
     3001 cctgcggttt ggcatcgcgc aggcgctgta aggtttcaac cgaaatcagc ggcacgtcgc
     3061 cgtaaagcat taaaatatct tcatcgtcgc taaaaaaggg cgcggcctgc tgcattgcgt
     3121 gacctgttcc caactgttcc gcctgaagca cccagttcag cttgtcatct ttcagggtct
     3181 gttttaacaa ctcgccaccg tggccataga ccagatgaac ctgtgcggcc cctaatttag
     3241 tagctgcatc aatgacatgc tgcaccatgg gtttacccgc cagcgtgtgc agcactttag
     3301 gaatatcgga atacatgcgc gtgcctttac ctgcggcaag gatcactacg ctcatagcac
     3361 tatttaacat acgcgtcctg actgtaattt gagaacgaat ttatactgtt tcacgttgaa
     3421 aatactacat ttttttcatc gtaaaatgga agaaggataa aacgctcacc gggataaaat
     3481 ccccgcctgc taatgaatca ttttcgttca ttaccgcgcc tcttgtctcc tgaaaagtaa
     3541 aaacacccgc gtattggcaa cgtagtccga tgtttttgct gtttttttac tccataaata
     3601 aagaagataa cgaaataaag cgcaggggag tcagaaaagc aaaaaccagc gacagaggcc
     3661 gctggttttc cgttgcgcgt attttttact taattacgcg acataaaaat ccgcaaaata
     3721 taccagaaca tggtcgcgat agaagcaaac agatgtaatg ccgcgccagc agggcgatcg
     3781 gtagggtaat ggtgaataat gttagaagtg tcgtaaagta taaacccggc gcacagcagt
     3841 accattagcg cagaaaacca gacgcccagc gaaaagccgc agatgacgct ggcaataatc
     3901 gcgccaaaag caatgaatcc agccatagtc agaaacgagc gcagaaaaga aaagtctttt
     3961 tttatggaaa acgcggtaaa cgtcagaccg ccaaccagca acaggggcgt tattgccgcc
     4021 gcgccaatgc tcgacgggtt aatatacgcc gccaccgtta acaggggggc aaaaatcagg
     4081 gattctgcca acacataaat ccccagcccg ataagttgcg tttgattagt ccccgcatta
     4141 tccgccagac gggtcgccag cattcccacc agcataaaag cgccgagaac aaccaaccag
     4201 ctatatcttc caccagccag cagcacatca agcgcatact ccccgccccc tataaaactc
     4261 cacgccgcgc tcaacacgat aaaaccgacg atggcgacgg cgagatgaag ataagcgcga
     4321 cgaataaagg tagtacgatc aatccttgag tcgggttgtg gccccgcaaa ggatggctga
     4381 aatgacatag taataatccc tcattttatg caataaaaac gcatccattc cttccttctt
     4441 cgcacaatgt gcagatgcca atgacagaaa gaaggattta atgaaaacag cgctgtcgct
     4501 gaaaacgcat cgccttcagc cgcttgtttt tgtcgttgct agtttatcga ataaaaattg
     4561 agaggataaa aaaaaccagt ccgcaatcag actggtttta tgctttcaag ccggtgttac
     4621 atcgcttttt tggtcaactc gataacgcgc agtttagcga tcgctttggc cagttccgca
     4681 gacgcctgag cgtaatccac gtcaccgtgc gagctcttaa tgtgctcttc ggctttacgc
     4741 ttcgcttcca gggctcgcgc ttcgtcgaga tcctgaccgc gaatcgcggt atccgccaga
     4801 acggtcacac tgccaggctg cacttccaga atgccgccgg acagatagat aaactcttcg
     4861 tgaccgtgct gcttaacgat gcgaatcata ccaggcttaa tggcggtgag cagcggcgcg
     4921 tgccccgggt agatccccag ttcaccttcg ctacccgtaa cctggatttt ctcgaccaga
     4981 ccggagaaca tttgttgctc cgcgctgacg acatccaggt ggtaagtcat tgccatatca
     5041 ccctccgatt aaggcgttaa agttttttgg ctttttccac ggcttcgtcg atggaaccga
     5101 ccatgtagaa cgcctgctcc ggcaggtgat cgtattcgcc ttccatgatg cctttaaagc
     5161 cacggatggt gtctttcagg gagacgtatt tgcccggaga accggtaaat acttccgcca
     5221 cgaagaacgg ctgggacagg aagcgctgga tcttacgcgc gcgagctacc accagtttat
     5281 cttcttcaga cagttcatcc ataccgagga tggcgatgat gtctttcagt tcctgataac
     5341 gctgcaggat ggactgaacg ccacgcgcgg tgtcgtagtg ttcctgacca acaaccagcg
     5401 gatccagctg acggctggtg gaatccagcg ggtcaacggc cgggtagata cccagggatg
     5461 cgatctgacg gctcagtacc acagttgcat ctaagtgcgc aaaggtggtg gctggagacg
     5521 ggtcagttaa gtcatccgca ggtacgtata ccgcctgtac ggaggtgata gaaccggtct
     5581 tggtggaggt gatacgttcc tgcagaacgc ccatctcttc cgccagagtc ggctggtaac
     5641 ctaccgcgga aggcatacga cccagcagtg cggatacttc cgtaccggcc agggtgtaac
     5701 gatagatgtt atcgacgaac agcagtacgt cacgaccttc gtcacggaat ttctccgcca
     5761 tggtcaggcc ggtcagtgca acgcgcagac ggtttcccgg cggctcgttc atctggccat
     5821 acaccaggga tactttatcg ataacgttgg agtcggtcat ttcatggtag aagtcgttac
     5881 cctcacgagt acgttcacct acgcccgcaa acacagagta accggagtgc tcgatcgcga
     5941 tgttacggat aagctccatc atgtttacgg ttttacctac acccgcacca ccgaacagac
     6001 cgactttacc gcccttcgcg aacggacaca tcaggtcgat aactttgata ccggtttcca
     6061 gcagttcctg agagtttgat aactcttcgt aggaaggcgc tgcgcggtga atcgcccaac
     6121 gctcttcttc gccgatctcg cctttcatgt cgaccggttc gcccaggacg ttcatgatac
     6181 gacccagcgt agctttacct accgggactt cgatcgggtg ttcgagatct tttacatcca
     6241 gaccgcgacg cagaccgtca gaagacccca tcgcgatggt acgcacgata ccgccgccaa
     6301 gctgctgctg aacttccagc accagcttct cattaccatt ctgcacctca agggcatcgt
     6361 acacgcgtgg tacggcatcc tgagggaact cgacgtctac cacggcgccg attacctgga
     6421 caatctttcc agtagccatc ttaaatcctc tacgaaataa cctggttaaa ccgcggcggc
     6481 ccccgagacg atctcggtga gttcctgagt aatgctggcc tgacgagctt tgttgtatac
     6541 taactgcagc tctttaatca ggctgccgcc attatcggtt gcggctttca tcgccaccat
     6601 tcgtgcggcc tgctcgctgg ccaggttttc taccacgccc tgataaacct gagactccac
     6661 ataacgacgc aggagagtat ccagcagcgc tttcgggtct ggttcataca ggtaatccca
     6721 ggctgtacgc ttcagatcat catcttctga cgccggcagc ggcagcagtt gagtgatcgt
     6781 cggcacctga gacatggtgt taataaattt gttgctgaca atgtaaagct tgtccagacg
     6841 gccttcgtcg taggcctgca acatcacttt aaccggaccg atcagttcgg acagagaagg
     6901 gttatccccc atacctgtca cctgagcgac aacgttgccg cctacggaat taaagaatga
     6961 cacgccctta gagccgatca ttgcgagttc gcactgaacg cctttatcgg accatgcctt
     7021 catatccgcc agcagctttt tgaacaggtt aatgttcaag ccaccgcaca aaccacagtc
     7081 ggtcgacact accaggtagc ccacgcgttt aacgtcgcgc tcttccaggt aggggtgctt
     7141 atattccaga ttaccgttcg caaggtgacc aatcactttg cgcatggtct ctgcataagg
     7201 acggctggcc gccatgcgat cctgcgattt acgcattttg gaagcggcga ccatctccat
     7261 cgctttagtg atcttttgcg tgttctggac gcttgcgatc ttactacgta tctcttttgc
     7321 gccggccatg agcttctcct caatgcctta cggcctgccc taaggcaagc cgccagacgt
     7381 taccaggact gggttgcttt gaaggaatcg aggatgcctt tcagcttgcc ttcgatttcg
     7441 tcgttatagc caccggactg gttgatctct tgcatcagcg gagcgtgatc acggtcgacg
     7501 taagccagca gtgcggcttc gaagctaccg attttcgcca gttcgacatc cgccagataa
     7561 ccacgttctg ctgcgaacag aaccagagac tgctgcgcga cggacatcgg cgcatactgt
     7621 ttctgtttca gcagttcggt cactttctga ccgtggtcaa gctgtttacg ggtggcatcg
     7681 tcaaggtcgg atgcaaactg agagaacgcc gccagttcac gatactgcgc cagcgcggta
     7741 cgaatacctc cggacagttt tttcatgatc ttggtctggg ctgcgccacc tacacgggat
     7801 accgagatac ccgggttaac cgcaggacga ataccggcgt taaacaggtt agattccagg
     7861 aagatctgac catcggtaat ggaaattacg ttggtcggaa cgaacgcgga aacgtcacct
     7921 gcctgcgttt cgataatcgg cagcgcagtc agtgaaccgg ttttcccttt cacttcacct
     7981 ttagtgaagg cttcgacgta gtcggcgtta acacgcgcag cacgctccag cagacgagag
     8041 tggaggtaga atacgtcgcc cgggaatgct tcacgtcctg gcggacgacg gagcagcagg
     8101 gagatctgac ggtaagcaac agcctgttta gacaggtcat cgtaaatgat cagcgcatct
     8161 tcaccgcggt cacggaagta ttcgcccatt gcgcaaccgg catacggcgc caaatattgc
     8221 agcgcagcgg attcggacgc ggtcgccacc acaacaatgg tgttagccag cgcgccgtgc
     8281 tcttccagtt tacgcaccac gttagagatg gtggacgctt tctggccgat agcgacatag
     8341 atacatttga tgccggagtc gcgctggttg atgatggcgt cgatagccag cgcggtttta
     8401 ccggtctgac ggtcaccgat gatcagttca cgctgaccac gaccgattgg gatcatggag
     8461 tcaacggctt tatagccggt ctgcaccggc tgatcgacag actgacgatc gataacgccc
     8521 ggcgcaatcg cttcaacggc agagaagccg tcattatcaa ccggaccttt accgtcgatt
     8581 ggcgcaccca gggtgtttac cacacgtccc agcagaccgc ggccaaccgg aacttccagg
     8641 atacgacccg tacatttaac cttcatgcct tcggcaaggt cagcgtatgg acccatgact
     8701 accgcaccca cggagtcgcg ctccaggttc agtgcgatag cgtaacggtt acccggcagg
     8761 gagatcattt caccctgcat acaatcggcc aagccgtgaa tgcggataac accgtcacta
     8821 acagaaacaa tagtaccttc gttgtgagct tcgctcacca cattgaactg agcaatgcgc
     8881 tgcttgatca gttcgctgat ttcggtggaa ttcagttgca tgctccagtc cccttaagac
     8941 tgcaagacgt ctgcaaggcg ctcaagacgg ccgcgtacgc tgccatcaat gaccatatca
     9001 cccgcccgga tgataacgcc tgccattaca gacttatcga ttttgcaatt cagcttcact
     9061 ttgcgtgaca gacgtttttc catcgcggcg ctgattttcg aaagctgctc ttcactcaat
     9121 gcggttgccg acgtaacttc tacctcggag gtagcttcac tggcggcacg cagatgaata
     9181 aactgctcca gaacatccgg gagcgcgttc agacgattat tttcagccat cacccgaatc
     9241 aggttctgac cgttttcgtc taactgctca ccgcagactg cgataaacga ctcagcgagc
     9301 gtttccggcg ccagcgcgcc agagagaagc tctgccattt gttcgttctt ggttacctcg
     9361 gcggcaaacg ccagcatatc ctgccagcgc tctacacttt ggtgttcaac ggcaaagtca
     9421 aaagctgctt tggcgtaggg gcgagctacc gtaacaaatt cagacatcag cccctccctc
     9481 cttacagttc agcgacaagt ttatccacga tgtcgctgtt agcagcttca tccacggaac
     9541 gttcgatgat cttctcggcg ccagcaacag ccaggatagc aacttgctta cgcagctctt
     9601 cacgggcacg tttacgctcg gcttcaattt ccgcctgcgc ctgcgccacg attttagtac
     9661 gttcctgctc tgcttcagtt ttggcttcgt ccaggatctg agcgcggcgt ttgtttgcct
     9721 gctcgatgat tacctgagct tccgctttcg cttttttcag ctggtcggtc gcgctggcct
     9781 ttgcaaggtc aagatcctta tgtgctcgtt cagcagaagc gagaccgtca gcaatttctt
     9841 tctgacgttt ctcgatggct gccattaacg gcggccatac gtacttcatg caaaaccaga
     9901 caaagagaat aaacgcgatg gcctggccga ggattgttgc gttaagattc acagcacaat
     9961 gcctctatct agttaacctt ctgatattgc tcttaattca agcaacgctt actacgcgac
    10021 agcgaacatc acgtacagac ccagacctac agcgatcatc gggatagcat ccaccagacc
    10081 cataacgata aagaactgag tacgcagcag aggaatcaga tcaggttgac gcgccgcgcc
    10141 ttccaggaat ttacccccga ggatgccgat accgatcgca gcaccgattg ccgccagacc
    10201 catcatcaca gcggcagcca tgtacagcag atccatattc aggttttcca tgacagtctc
    10261 cagtttgttt cagttaaaac gtagtagtgt tggtaaatta atgctcttcg gacgccatcg
    10321 acagatagac aatcgtcaga accatgaaaa tgaaggcttg cagcgtaata atcaggatgt
    10381 ggaaaatggc ccacggcaca ttcagaatcc actgtgacca ccacggcaac agaccagcaa
    10441 tcagaatgaa aatcagctca ccggcataca tgttgccgaa cagtcgcaga ccgagagaaa
    10501 ccggtttgga cagcagactt accccttcaa ggattaagtt gacaggaata aacgcccagt
    10561 gattgaacgg ctgcagcgtc aactcttttg cgaagccgcc gatgcctttc attttgatgc
    10621 tgtagaacag aataaggatg aatacgccca gcgccatcga cagggtgatg ttgacgtcag
    10681 cagacggcac cacgcgcgtt gccggcagac ccagccaatg ctcagcgata tacggcagca
    10741 ggtcgatagg cagtaagtcc atcaggttca taaggaatac ccagacgaaa atcgtcaggg
    10801 ccagcggcgc aatcagcttg cttttgccat ggtacatgtc tttgacgctg ccatgcacaa
    10861 agccgactat cagctcaatc gcggtctgaa acttgcctgg cacgccgctg gtcgcttttt
    10921 tagcaacgct acggaacatc accagaaaca acagacccag caccaccgag aagaacatgg
    10981 agtcaatatt gagcgtccag aaggtggctg gggggttctg cggatccacc agcgagaaag
    11041 tacgcaggtc cagctgaagg ttattcagat ggtgtcctat gtattcctgc ggcgtcatat
    11101 tttctgaagc catgatgcct tttacccttt gttgttaatt acagccggcg ccagtatctg
    11161 aaccaccagc accaaaaccc acgtaacgat cagcggcaaa aacaccgcct ttaaaaccgc
    11221 caacgccacc accagtaaaa ccagcatcgc taacaccttg aaggcttcac cgaaggcgaa
    11281 agtccaggac acgcggccct tagcaggtgt atgcgcctgg tgacgccagg caaatatcat
    11341 aaacaacata ttaggcagtg ccactgccaa tcccccacat actgcggaga tgccccagaa
    11401 ggggtctttg aggcaaaaca gcaatccact tgctattacc gccagaaact gaatgaacag
    11461 aagcttacga gcaacgtttc gactcacgag cgacacaggc atcacgtttt tactcctgct
    11521 cacttcgagg tatgccgcgt gtcgtataaa acgttcttta agacttagag tcaagcatca
    11581 aaaagcggtc aaattatacg gtgcgccccc gtgatttcaa acaataagta gccaaaaggt
    11641 gaataaatgt ttaaatattt ttctctggcc cgcattttta acttttagct aaagtgtgaa
    11701 cgatcgtaca aaactgcaaa tagcgcgaaa acactggcga taaagcgtgc accagatcac
    11761 acattaaaca tattcatgct tacgcaattc atttacgtgt caattcatgc cttttcatct
    11821 ttttgatatt taagcgtaaa accaggtact
//
LOCUS       DAJVBX010000151        11848 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.151, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000151 DAJVBX010000000
VERSION     DAJVBX010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 11848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11848
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.151"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(114..2615)
                     /gene="copA"
                     /locus_tag="OPV72_003345"
     CDS             complement(114..2615)
                     /gene="copA"
                     /locus_tag="OPV72_003345"
                     /EC_number="7.2.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-exporting P-type ATPase CopA"
                     /protein_id="HCR9915558.1"
                     /translation="MSQTIDLTLDGLSCGHCVKRVKESLEQRPDVELADVTVTEAHVT
                     GTASADALIETIKQAGYGATLSHPKAKPLTESSIPSEALAAVPHELPVATADEESQQL
                     LLSGMSCASCVTRVQHALQSVPGVTQARVNLAERTALVMGSASAADLVQAVEKAGYGA
                     EAIEDDIKRRERQQETAIATMKRFRWQAIVALAVGIPVMVWGMIGDNMMVTGDNRSLW
                     LAIGLITLAVMVFAGGHFYRNAWKSLLNGTATMDTLVALGTGVAWLYSMSVNLWPQWF
                     PMEARHLYYEASAMIIGLINLGHMLEARARQRSSKALEKLLDLTPPTARVVTEDGEKS
                     VPLADVQPGMLLRLTTGDRVPVDGEITQGEAWLDEAMLTGEPIPQQKGEGDSVHAGTV
                     VQDGSILFRASAVGSHTTLSRIIRMVRQAQSSKPEIGQLADKISAVFVPVVVAIALFS
                     AAIWYFFGPAPQIVYTLVIATTVLIIACPCALGLATPMSIISGVGRAAEFGVLVRDAD
                     ALQRASTLDTLVFDKTGTLTEGKPQVVAVKTFNGVDEAQALRLAAALEQGSSHPLAHA
                     ILEKAGDDKLPQVNGFRTLRGLGVSGEAEGHQLLLGNQALLNEQHVATDDMTAEITAQ
                     ASQGSTPVLLAIDGKAAALLAVRDPLRSDSIAALERLHNAGYRLVMLTGDNPTTANAI
                     AKEAGIDEVIAGVLPDGKADAIKRLQSQGRQVAMVGDGINDAPALAQADVGIAMGGGS
                     DVAIETAAITLMRHSLMGVADALAISRATLRNMKQNLLGAFIYNSIGIPVAAGILWPF
                     TGTLLNPVVAGAAMALSSITVVSNANRLLRFKPKA"
     gene            2725..3141
                     /gene="cueR"
                     /locus_tag="OPV72_003346"
     CDS             2725..3141
                     /gene="cueR"
                     /locus_tag="OPV72_003346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(I)-responsive transcriptional regulator"
                     /protein_id="HCR9915559.1"
                     /translation="MNISDVAKKTGLTSKAIRFYEEKGLVTPPLRSENGYRTYTQKHL
                     NELTLLRQARQVGFNLEECGELVNLFNDPRRHSADVKKRTLEKVAEIERHISELQSMR
                     DQLLAMAESCPGDDSADCPIIDNLSGCCHHKAQKLR"
     gene            complement(3142..3594)
                     /locus_tag="OPV72_003347"
     CDS             complement(3142..3594)
                     /locus_tag="OPV72_003347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HCR9915560.1"
                     /translation="MIAMILVHPHIFWLSLGGLLLAAEMLGGNGYLLWSGVAAVITGL
                     TVWLLPLGWEWQGVLFAALTLLAAWLWWRWLARRVREQKPTDSRLNQRGQQLVGRRFM
                     LDAALVNGRGHMRVGDSSWPVCADEDLRAGTHVEVIAVEGITLRIRAV"
     gene            complement(3591..4509)
                     /locus_tag="OPV72_003348"
                     /pseudo
     CDS             complement(3591..4509)
                     /locus_tag="OPV72_003348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459496.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH/Band 7/PHB domain protein"
     gene            4656..5333
                     /gene="fetA"
                     /locus_tag="OPV72_003349"
     CDS             4656..5333
                     /gene="fetA"
                     /locus_tag="OPV72_003349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter ATP-binding protein FetA"
                     /protein_id="HCR9915561.1"
                     /translation="MTKRSMLLELKQVGYQTATTKIVNNISFTLQRGEFKLITGPSGC
                     GKSTLLKMVASLISPDIGVILFEGRDITTLSPEAYRQQVSYCAQTPALFGDTVYDNLI
                     FPWQIRHQRPQPTAFADDLARFELPETILQKPIAALSGGEKQRIALIRNLQFLPKILL
                     LDEITSALDEHNKRNVNDIIHRYVRDKQVAVLWVTHDKDEIQHADKVITLTPSAGEMQ
                     EARYERA"
     gene            5320..6099
                     /gene="fetB"
                     /locus_tag="OPV72_003350"
     CDS             5320..6099
                     /gene="fetB"
                     /locus_tag="OPV72_003350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron export ABC transporter permease subunit
                     FetB"
                     /protein_id="HCR9915562.1"
                     /translation="MNEHNITNTSLALSMLLVVVAMLISHKEKLALEKDILWSVCRAV
                     IQLIIVGYVLKYIFGVNHAALTLLMVLFICFNAAWNAQKRSKYIDKAFLSSFIAITVG
                     AGLTLTVLVLTGSIEFAPMQVIPIAGMVAGNAMVAVGLCYNQLGLRFHSEQQQIQEKL
                     SLGATPKMASAGLIRDSIRASLIPTIDSAKTVGLVSLPGMMSGLIFAGIDPVKAIKYQ
                     IMVTFMLLSTASLSTIIACYLTYRKFYNSRHQLVVMPLKKS"
     gene            complement(6185..7039)
                     /gene="cnoX"
                     /locus_tag="OPV72_003351"
     CDS             complement(6185..7039)
                     /gene="cnoX"
                     /locus_tag="OPV72_003351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperedoxin"
                     /protein_id="HCR9915563.1"
                     /translation="MSVQNIVNINESNLQQTLEQSMTTPVLFYFWSERSQHCLQLTPV
                     LESLAAQYHGQFILAKLDCDAEQMIAAQFGLRAIPTVYLFQNGQPVDGFQGPQPEEAI
                     RALLDKVLPREEELKAQQAMQLMQEGNYVDALPLLKDAWQLSSQNSEIGLLLAEAQIA
                     LNRSEEAEAVLKTIPLQDQDTRYQGLVAQIELLKQAADTPEIQQLQQQVADNPQDAAL
                     ATQLALQLHQVGRNEEALELLFSHLRKDLAAAEGQTRKTFQEILAALGTGDALASKYR
                     RQLYALLY"
     gene            complement(7099..7869)
                     /locus_tag="OPV72_003352"
     CDS             complement(7099..7869)
                     /locus_tag="OPV72_003352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCR9915564.1"
                     /translation="MQKSVLITGCSSGIGLDSALELKRQGFQILAGCRKPDDVARMNS
                     MGFTGVLIDLDSPESVDRAADEVIALTDNRLYGIFNNAGYGVYGPLSTISREQMEQQF
                     SSNFFGAHQLTMRLLPAMLPHGEGRIVMTSSVMGLISTPGRGAYAASKYALEAWSDAL
                     RMELRHTGIKVSLIEPGPIRTRFTDNVNQTQRDKPVENPGIAARFTRDPDAVVAKVRH
                     AFASDKPRLRYPVTLVTWAVMALKRILPGRMLDKILQS"
     gene            complement(8024..8638)
                     /gene="tesA"
                     /locus_tag="OPV72_003353"
     CDS             complement(8024..8638)
                     /gene="tesA"
                     /locus_tag="OPV72_003353"
                     /EC_number="3.1.1.5"
                     /EC_number="3.1.2.14"
                     /EC_number="3.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multifunctional acyl-CoA thioesterase I/protease
                     I/lysophospholipase L1"
                     /protein_id="HCR9915565.1"
                     /translation="MNFNTVFRWHLPFLFLILLTFRAAAADTLLILGDSLSAGYRMTA
                     SAAWPSLLNDKWQNKTSVVNASISGDTSQQGLARLPALLQQHHPRWVVVELGGNDGLR
                     GFAPAQTEQTLRKIIQTVKAADAQPLLMQIHLPANYGRRYNESFSAIYPKLAKEFDIP
                     LLPFFMEEVYLKPQWMQDDGIHPNRDAQPFIADWMAKQLTPFLS"
     gene            8609..9295
                     /locus_tag="OPV72_003354"
     CDS             8609..9295
                     /locus_tag="OPV72_003354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR9915566.1"
                     /translation="MPAENSVEVHRLRKSVGQGEHELSILTGVELVVKRGETIALIGE
                     SGSGKSTLLAILAGLDDGSSGEVSLVGKPLHQMDEEARAQLRAQHVGFVFQSFMLIPT
                     LNALENVELPALLRGENSGQSKAGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARA
                     FNGRPDVLFADEPTGNLDRQTGDKIADLLFSLNREHGTTLILVTHDPALAARCDRRLR
                     LVNGQLQEEA"
     gene            9292..11706
                     /locus_tag="OPV72_003355"
     CDS             9292..11706
                     /locus_tag="OPV72_003355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR9915567.1"
                     /translation="MIARWFWREWRSPSLIIVWLALSLAVACVLALGSISDRMEKGLS
                     QQSREFMAGDRTLQSSREVPKAWLEEARKRGLNVGEQLTFATMTFAGDTPQLASVKAV
                     DSVYPMYGELQTRPGGVKPQPGSVLLAPRLMALLNLKTGDTIDVGDVTLRIAGEVVQE
                     PDSGFNPFQMAPRLMMNMADVAKTGAIQPGSRVMWRYKFGGTPQQLAGYESWLLPQLK
                     PEHRWYGLEQDDGALGKSLERSQQFLLLSALLTLLLAVAAVAVAMSHYCRSRYDLVAI
                     LKTLGAGRAQLRKLIIGQWLMVLGLSAVTGGAIGLLFENILLVLLKPVLPADLPPASL
                     WPWLWALGAMTVISLLVGLRPYRLLLASQPLRVLRRDVVARVWSLKIYLPVACAVVVA
                     LLAGLMGESMLLWAVLAGAVILALLCGLVGWMLLNVLRGMTLTSLPLRLAVSRLLRQP
                     WSTLSQLSAFSLSFMLLALLLVLRGDLLDRWQQQLPPESPNYFLINIASEQVAPLKAF
                     LAEHQVIPQTFYPIVRARLTEINGNPTEGQQDESLNRELNLTWQDTRPAHNPLVAGHW
                     PPKPGEVSMEEGLAKRLNVKLGDSVTFMGDTQAFSAKVTSLRQVDWESLRPNFFFIFP
                     SGALDGQPQSWLTSFRWENGNGMLTQLNREFPTVSLLDIGAILKQVGQVLEQVSRALE
                     VMVVLVTLCGMLLLLAQVQVGMRQRHQELVVWRTLGAGKKLLRTTLWCEFAMLGLVAG
                     LVAAIGAETALAILQINVFDFPWEPDWRLWVALPFCGALLLSVCGGWLGVRLLKGKAL
                     FRQFSG"
BASE COUNT         2530 a         3191 c         3360 g         2767 t
ORIGIN      
        1 aatctgctcc cggcagattt gtcgctcacc ccagtcacat agttatctat gctcctgggg
       61 actcactccc ttgccgcctt taagcaactc gaattatttt gggtatagac tttttacgct
      121 ttcggtttaa agcgcaatag ccggttggca ttgctgacga cggtaatgga agacagcgcc
      181 attgccgcgc ccgctactac cgggtttaac aaggtaccgg taaacggcca cagaataccg
      241 gcggccaccg ggataccaat gctgttgtag ataaatgcgc caagcaggtt ttgtttcata
      301 ttgcgcaacg tcgcgcgcga aatggccagc gcatccgcca cgcccatcag actatggcgc
      361 atcagcgtaa tcgccgcggt ttcaatcgcc acatcgctgc caccgcccat cgcgataccg
      421 acgtccgcct gcgccagcgc gggcgcatcg ttgataccat cgccgaccat cgcaacctga
      481 cgaccctggc tttgcaggcg tttaatcgca tcggctttgc catccggcag aacgcccgca
      541 atcacttcat caatacccgc ttctttggca atcgcgttag ccgtcgttgg gttatccccg
      601 gtgagcatta ccagacggta tccggcattg tgcaggcgtt caagtgcggc aatactatcg
      661 ctgcgcaatg gatcgcgtac cgccagtaac gccgccgctt taccgtcaat cgccagcagg
      721 actggagtcg agccttgcga ggcctgcgcg gtgatttccg ccgtcatatc atccgtggcg
      781 acgtgctgtt cgttcagtaa cgcctggttc cccagaagca gttgatgacc ttccgcttca
      841 ccgctgacgc ccagtccgcg cagcgttctg aaaccgttca cctgcggcag tttatcatcg
      901 ccggcttttt ccagaatcgc atgggccagc gggtggctgg agccttgttc gagcgcggct
      961 gccagacgta atgcctgagc ttcatcaacg ccgttaaagg tttttaccgc caccacttgc
     1021 ggcttgcctt ccgtcagcgt cccggtttta tcaaaaacga gggtatccaa cgtactggcg
     1081 cgttgcaggg catcggcgtc gcgtaccagc acgccgaatt cggccgcgcg gcctacgccg
     1141 gaaataatcg acattggcgt cgccaggcct aatgcgcaag ggcaggcgat aatcagtacg
     1201 gtggtggcga tgaccagcgt ataaacaatt tgcggtgccg gcccgaagaa ataccagata
     1261 gcggcgctga acagcgcaat ggccaccact acgggaacga ataccgcgga gattttatcg
     1321 gccagttggc caatttccgg tttactgctc tgcgcctggc gtaccatgcg aataatgcgt
     1381 gacagcgtgg tatgactgcc caccgcgctg gcgcggaaca ggatgctgcc gtcctggacg
     1441 acggtgccgg catgaacgct gtcgccttcg cctttttgct gcggaatagg ttcgccggtc
     1501 agcatggctt catcaagcca cgcttcgccc tgggtaattt cgccatccac cggcacgcga
     1561 tcgccggtag tgagccgcag cagcatccct ggctgaacgt ccgccagcgg gacgcttttt
     1621 tcgccgtctt ctgttacgac gcgtgcggtg ggcggggtga gatcgagtaa tttttccagc
     1681 gcttttgagg aacgctgacg ggcgcgcgct tccagcatgt gtccgagatt aatcagaccg
     1741 ataatcatcg cgctggcttc gtaatagagg tgccgtgctt ccatcgggaa ccactgcggc
     1801 cacaggttga cgctcatgga gtagagccag gcgaccccgg tgccgagcgc caccagcgta
     1861 tccatcgtcg ccgtgccgtt cagcaggctt ttccacgcgt tacggtaaaa gtgaccgccc
     1921 gcaaaaacca tcaccgcaag cgtgatcagg ccaatagcca gccacaggct gcggttgtcg
     1981 ccggtcacca tcatgttatc gccgatcatc ccccagacca tgaccggtat accgaccgcc
     2041 agggcgacga tggcctgcca gcgaaaacgt ttcatggtgg cgatggcggt ttcctgctgg
     2101 cgctcgcggc gtttgatgtc atcttcaatc gcctctgcgc cgtagccggc tttttccacc
     2161 gcctgcacta aatcagcggc ggacgcgctg cccatcacca gcgcagtgcg ttccgccagg
     2221 tttacccgtg cctgcgtgac gcccggtacg ctttgtagcg catgttgtac gcgggtgaca
     2281 caactggcgc agctcatgcc gcttaacagc aactgttggc tttcttcatc ggccgtcgct
     2341 accggaagct catgaggaac cgctgccagt gcttccgacg ggattgatga ctccgtcagc
     2401 ggtttagcct ttgggtggct taacgtcgcg ccatacccgg cttgtttgat ggtttcaatt
     2461 aacgcgtccg cactggcggt accggtaacg tgcgcttcgg ttacggtaac gtccgccagc
     2521 tcaacatccg gacgttgttc aagactttct ttcacgcgtt taacgcaatg accgcaggac
     2581 aaaccgtcca gggtcaggtc gatagtttga gacatagtaa aaactccttt atgattggtc
     2641 atcaattcat tgacattagt aatcgtagtg actcactgtg ataaaggtta aaccttccag
     2701 caaggttaag gtcaaggggg aaatatgaat attagcgatg tggcgaaaaa aaccggttta
     2761 accagcaaag ccattcggtt ttatgaagag aaagggctgg tgacgccgcc attacgtagc
     2821 gaaaatggtt atcgcaccta cacgcagaag catttaaacg agctgacgtt gctgcgacag
     2881 gcgaggcagg tggggtttaa tctggaagag tgtggcgaac tggtcaatct gtttaacgat
     2941 ccgcgacgcc atagcgcaga tgtgaaaaag cggacgctgg aaaaggtcgc ggagatcgaa
     3001 cgccatatca gcgagctgca atcaatgcgc gatcaactgt tggcgatggc ggagagttgt
     3061 cccggcgatg acagcgccga ctgcccgatt attgataatc tttccggctg ctgtcatcac
     3121 aaggcgcaaa agttacgttg attaaacggc gcgaatgcgt agggtgatgc cttccacggc
     3181 gatcacttcg acatgcgtac ctgcgcgcag gtcttcgtca gcgcataccg gccacgagct
     3241 gtcaccgaca cgcatatgac cccgtccgtt cactaacgcg gcatcaagca taaaccggcg
     3301 gcctaccagt tgttgtccgc gttggttaag gcggctgtcg gtcggctttt gttcccgcac
     3361 gcgacgcgcc agccagcgcc accaaagcca ggccgccagc aacgttaagg ccgcaaacag
     3421 cacgccctgc cattcccagc cgagcggtaa gagccagacg gttaagccgg taatcactgc
     3481 cgccacgccg ctccacagca aatagccgtt accgccgagc atttccgcag ccaacaacag
     3541 gccgccgagg ctaagccaga agatatgtgg atgtaccaga atcatcgcta tcatgctttt
     3601 ttccgttcgc tggcgctgtc cttaaccagc tcgctgatcc cggcgatagc gcccatcaga
     3661 ctgctggcat ccagcggcat catgaccact ttgctgttat tcgccgagcc gatttgctgt
     3721 aacgcttcgg tgtatttctg cgccacgaag tagtttaacg cctgaatatc cccggcggcg
     3781 atggcttcag acaccatctg cgtagcgcgg gcttccgctt cggcggaacg ttcgcgcgct
     3841 tccgcctgca ggaaagcgga ctgacgttcg ccttcggctt tcagaatctg cgactgtttt
     3901 tccccctcgg ctttcaggat ttccgcctga cgcacccctt cggcctcaag gatataggcg
     3961 cgtttggtac gttccgcttt catctgggcg ttcatcgagg agatcaattc cgcgggcgga
     4021 cggacatcgc gaatttcgat acgggtaact ttaattcccc acggattggt ggcttcatcg
     4081 acaatatgca gcagccgcgc gttgatgctg tcgcgctggg agagcatttc atccagctcc
     4141 atcgaaccga gcaccgtacg gatattggtc atggtcaggt taatgatcgc cagttccagg
     4201 ttactgactt caataagcgg cgcgcggcgc atcgataacc tgaataaaac agaccgcatc
     4261 gatagtgacg ttggcgttat cttttgagat cacctcctgc gacggaatat ccagcacctg
     4321 ctccatcata ttgatcttgc ggccaattct gtccataaac ggtacaacaa ggcttaatcc
     4381 cggctgcaga gttttggtgt aacgtccaaa gcgctccacc gtccactggt atccctgcgg
     4441 aacgattttg acgcccgcgc cgacgatcac cagcgcgacg aaaatgagaa tagggataag
     4501 aatgagcata gctaaacctc ctgttgcgtt gtccataaac cgattttgct gacgaattaa
     4561 gcgaattata cctgattcag taaagcatgt tcccccctta ttaattacag ggatacacta
     4621 tcgctataaa aatatgaaca acggatgcgc aataaatgac aaaacgtagc atgttgcttg
     4681 agttaaagca ggtcggttac cagactgcga cgacaaaaat agtgaataac atcagtttta
     4741 cgctgcaacg cggcgaattt aagttaatta ccggtccttc tggctgcgga aaaagtacgt
     4801 tgttgaaaat ggtggcctcg ctaataagcc ctgatatcgg cgtgattctt tttgaggggc
     4861 gggatattac tactctgagt ccggaagcct atcgccagca ggtttcttat tgcgctcaga
     4921 cgccagcgct attcggcgat acggtttacg ataacctgat ttttccctgg caaattcgcc
     4981 atcagcgccc gcagccgaca gccttcgcag acgatctggc gcgttttgaa ctgccggaga
     5041 cgattctgca aaaaccgatt gccgcgcttt ccggcgggga aaaacagcgt attgctctaa
     5101 ttcgtaatct acagtttctg ccgaaaatac tgttactcga cgaaataacc agcgcgctgg
     5161 atgaacataa caaacggaat gtgaatgata ttattcatcg ctatgttcgc gataagcagg
     5221 tcgctgtctt gtgggtaacg catgataaag atgaaattca acacgcggat aaggtgataa
     5281 cgttaacgcc atctgccgga gagatgcagg aggcgcgtta tgaacgagca taatattacc
     5341 aatacctcgc tggcgttatc gatgctgctg gtggtggtcg cgatgctcat cagtcacaag
     5401 gaaaagctgg cgctggaaaa agatattctg tggagcgtat gccgggcggt gatacagctc
     5461 attattgtcg gctatgtact gaaatacatc tttggcgtta atcatgccgc cctgacgcta
     5521 ctgatggtgc tgttcatctg ttttaacgcc gcatggaacg cgcaaaagcg cagtaaatat
     5581 atcgataagg catttctctc ctcgtttatc gccatcaccg tcggcgccgg actaacgctg
     5641 acggtactgg tgcttaccgg ttcgattgaa tttgcgccga tgcaggtgat tcccatcgct
     5701 ggcatggtcg ccggcaatgc gatggtggcg gtagggctgt gctacaacca actggggctg
     5761 cgttttcata gcgagcagca gcaaatccag gaaaaattaa gtttgggcgc aacgccgaaa
     5821 atggcctccg ccgggcttat ccgcgatagc atccgcgcat cgcttatccc gacgatcgac
     5881 tcggcaaaga ccgttgggct ggtgagcctg ccggggatga tgtccgggct gatttttgcc
     5941 gggatcgatc cggtaaaagc gattaaatat caaattatgg taacgtttat gctgttatcg
     6001 acagccagcc tgtctaccat cattgcctgc tatttaacct accggaagtt ctataattcg
     6061 cgtcatcagt tggtagtgat gccgctcaag aaatcatgat agttgccgga tgatggcgca
     6121 agcgccttat ccggcctgag gacgacaggt aggccagata agcgcgccat caggcaagag
     6181 aggattaata cagtagcgcg tacaactggc ggcggtattt cgacgccagc gcgtcgccgg
     6241 tgccgagcgc ggcaaggatc tcctggaagg ttttgcgcgt ctgtccctcg gcggcggcaa
     6301 gatcttttct cagatggctg aacagcaatt ccagcgcttc ttcattacgt ccgacctggt
     6361 gcaactgcaa cgccagttgc gttgccaaag ccgcatcctg cggattatcc gcgacttgct
     6421 gctgaagttg ctgaatttcc ggcgtatccg ccgcctgttt aagcagttcg atctgcgcga
     6481 ccagcccctg ataacgggta tcctgatcct gtagcgggat agtttttaat accgcttcgg
     6541 cctcttcaga gcggttcagc gcaatttgcg cttccgccag taacaggcca atctcactgt
     6601 tctgcgaaga gagctgccag gcgtctttga gtaacggcag tgcgtcaacg tagttgccct
     6661 cctgcattaa ctgcatcgct tgttgcgctt ttagctcttc ttcacgcggc agtactttat
     6721 ccagcagagc gcggattgcc tcttccggct gcggcccctg gaaaccatcg accggttggc
     6781 cattctggaa cagatagact gtcgggatgg cgcgtagacc aaactgagcg gcgatcatct
     6841 gttcggcgtc gcagtccagc tttgccagaa taaactgacc gtggtactgg gcagccagac
     6901 tttccagcac tggcgttaat tgcagacagt gttggctgcg ttcagaccag aaatagaaca
     6961 gtaccggcgt ggtcatggac tgctctaagg tctgctgcag gttggattca ttaatattga
     7021 caatgttctg tacggacatg gcgtcgctct cttttgtctg tgtcacgttt acatgggggc
     7081 tgacgggcgc gcttcaactc agctttgtaa aattttatcc agcatccggc ccggcaatat
     7141 gcgtttcagc gccatcaccg cccaggtgac cagcgtaacg ggatagcgca gcctgggttt
     7201 atcgcttgca aaagcatgac gcactttcgc tactaccgcg tcaggatcgc gggtgaaacg
     7261 cgcggcgatg ccgggatttt ctaccggttt atcacgctgc gtctggttaa cgttatcggt
     7321 aaaacgggta cgaatcggcc ccggttctat caggctcact ttaatgcctg tgtgccgtag
     7381 ctccatacgt agcgcgtcag accaggcttc gagcgcatat ttgctggcgg cgtaagcgcc
     7441 gcgccctggg gtggaaatca gccccatcac cgatgaggtc atcacaatgc gtccttcgcc
     7501 atgcggcaac atggcgggaa gtaagcgcat ggtaagctga tgcgcgccga agaaattact
     7561 ggaaaactgt tgctccatct gttcacggct gatggtggaa agggggccat acacgccgta
     7621 gccggcattg ttaaagatcc catacagacg attatcggtc agggcgatca cttcatcggc
     7681 ggcacgatcc acgctttcag gggagtcgag atcgatcaac acgccggtaa atcccatact
     7741 gttcatccgg gcgacatcat caggtttgcg gcagcccgcc aggatttgaa agccctggcg
     7801 tttaagttca agcgcgctgt ccagaccgat tccgctggaa catcctgtta ttaagaccga
     7861 tttttgcata actttacctg tcaggatctc cgttgattta agagtcgtgg ttaactatat
     7921 ccgtcatact tcaagttgcc tgtgcgttcg tttactccag tcacataggt atctatgctc
     7981 ctggaaattc tcttacgtgc cgccttcatg caactcgaat gattcaggag agaaaagggg
     8041 tcaactgctt cgccatccag tcggcaataa acggctgcgc gtcgcggttg ggatgaatac
     8101 cgtcatcctg catccactgt ggtttcagat atacctcttc cataaaaaac ggtaatagag
     8161 gaatatcgaa ctctttggcg agcttaggat aaatggcgct aaaggattca ttataacggc
     8221 gaccgtagtt agcgggcaga tgaatttgca tcagtaacgg ttgggcatcg gcggctttca
     8281 ccgtctgaat gattttacgt agcgtctgtt cggtttgcgc aggcgcaaaa ccgcgtaggc
     8341 catcgttgcc gccaagctcc accactaccc agcgcgggtg atgctgttgc aacagcgccg
     8401 gcaaacgcgc cagtccctgc tgcgaggtat ccccgcttat actggcatta acgaccgacg
     8461 ttttgttttg ccatttatca ttaaggagcg acggccatgc cgcgctggcg gtcatacggt
     8521 aaccggcgct gaggctatcg cccagaatta ataaggtgtc tgcggcggcg gcacggaaag
     8581 ttaacaggat caaaaacagg aagggcaaat gccagcggaa aacagtgttg aagttcatcg
     8641 tctcaggaag tccgtcggtc agggtgagca tgagctttcc atccttaccg gagttgaact
     8701 ggttgtcaaa cgcggcgaaa ccattgcgct gattggcgaa tcaggatcgg gaaaatctac
     8761 gctgctggcg attctcgccg gactggatga cggcagtagc ggagaggtca gtctggtcgg
     8821 gaaaccgctt catcagatgg acgaagaggc gcgggcgcag cttcgcgctc agcatgtcgg
     8881 ttttgttttt caatccttca tgcttattcc tacgcttaac gcgctggaaa acgttgagct
     8941 accggccctg ctacgcggtg aaaacagcgg tcagagtaag gcgggggcga aagcgctgct
     9001 cgaacaactg ggactgggaa aacggcttga ccaccttccg gcacagcttt ccggcggcga
     9061 acagcagcgc gtagcgctgg cgcgcgcgtt taacgggcgt cctgatgtgc tgtttgccga
     9121 tgagccgacg ggcaaccttg accgtcagac cggagataaa atcgccgacc tgctattttc
     9181 gcttaaccgc gagcacggca ctacgctgat tctggtgacg cacgacccgg cgctggcggc
     9241 gcgctgcgac cggcggctac ggttggtcaa cggtcagtta caggaggagg catgatagcc
     9301 cgctggttct ggcgcgaatg gcgctcgccg tcgctgatta ttgtctggct ggcgttgagt
     9361 ctggcggtgg cctgcgtact ggcgctcggc agtatcagcg accggatgga aaaagggtta
     9421 agtcagcaaa gccgcgagtt tatggcaggc gatcggacgc tgcaaagttc gcgggaggta
     9481 ccgaaagcct ggcttgaaga ggcgcgtaaa cgcggcctta acgtgggcga gcagttaacc
     9541 tttgcgacca tgacgtttgc cggcgatacg ccgcaactgg ccagcgtgaa ggcggtagat
     9601 agcgtttatc cgatgtacgg cgaattgcaa acccgtccag gcggagtgaa accgcagccg
     9661 ggtagcgtac tgctggcgcc gcgtctgatg gcgctgctta atttgaaaac gggcgatacc
     9721 attgatgtcg gcgacgtgac cttgcgtatt gctggtgaag tggtgcagga gccggattcc
     9781 ggatttaacc cttttcagat ggcgccgcgt ctgatgatga atatggccga tgtggcaaaa
     9841 accggtgcga tacagccggg gagtcgcgtg atgtggcggt ataaattcgg cggaacgccg
     9901 caacagcttg ctggctatga aagctggctg ttaccgcagc ttaaaccgga acatcgctgg
     9961 tacggactgg agcaggatga cggggcattg gggaaatcgc tcgaacgttc gcagcagttt
    10021 ttgctgcttt cggcgttatt aacgctactg ctggcggtag ctgccgtcgc ggtggcgatg
    10081 agccattact gccgtagccg ctacgatctg gtggcgattt taaaaacgtt gggcgcgggc
    10141 cgggcccagt tgcgtaaact tatcatcgga cagtggttga tggtgctggg gctttccgcc
    10201 gtcacgggag gcgcgattgg gttactgttt gaaaacatat tgctggtgct gctaaaaccg
    10261 gtattgcccg ccgatttgcc gcccgccagc ctgtggccct ggctgtgggc gctgggcgcg
    10321 atgacggtca tctctctgct ggtcggttta cggccttatc gattgttgct ggcgagccag
    10381 ccgctacggg tgctgcgccg cgatgttgtc gctcgcgtct ggtcgttaaa aatttatttg
    10441 cctgtcgcct gcgccgtcgt ggtggcgctg ctcgccggat tgatgggcga aagtatgctg
    10501 ttgtgggcgg ttctggcggg cgccgtgata ctggcgctgc tgtgcggtct ggtgggctgg
    10561 atgctgctta acgtgttgcg cggcatgacg ttgacgtcgc taccgctgcg tctggccgtc
    10621 agccgacttc tgcgtcagcc gtggtcaacg ttgagtcagc tttcggcgtt ttcgctttcg
    10681 tttatgctgc tggcgctctt gctggtgctg cgcggcgacc tccttgatcg ctggcaacag
    10741 cagctcccgc cggaaagccc gaactatttc cttatcaata ttgcttcaga acaggtcgcg
    10801 ccgctgaaag cctttttggc ggaacatcag gtgatcccgc agacgtttta tccgattgtg
    10861 cgggcgcggt taacggagat aaacggtaat ccgacggaag gtcagcagga tgagtcgctc
    10921 aaccgtgaac tgaatttgac ctggcaggat acgcgcccgg cgcataatcc gctggtcgcc
    10981 ggtcactggc cgccaaaacc gggcgaagtc tctatggaag aggggctggc gaagcggctg
    11041 aacgtcaaac tcggcgatag cgtaaccttt atgggcgata cccaggcatt tagcgctaaa
    11101 gtcaccagcc tgcgtcaagt ggactgggaa agcctgcggc ccaacttttt cttcattttt
    11161 ccttccgggg cgctggacgg gcaaccacaa agctggttga ccagttttcg ctgggagaat
    11221 ggcaacggca tgttaacgca gcttaaccgc gagtttccta ccgtcagcct gttagatatc
    11281 ggggcgatcc tgaaacaggt gggacaggtg ctggagcagg tcagtcgggc gctggaggtg
    11341 atggttgtgc tagtcactct ctgcggcatg ttgctattac tggcccaggt acaggtcggg
    11401 atgcgtcagc gccatcagga gctggtggtg tggcgcacgt taggagccgg aaagaaactg
    11461 ttgcgtacca cactctggtg cgaattcgcc atgctggggt tagttgccgg gctggtcgcc
    11521 gcgattggcg cggagacggc gctggcgatc ttacaaatca acgtttttga tttcccctgg
    11581 gagccggact ggcgtttatg ggtcgcactg ccgttttgcg gcgcgctgct gctttccgta
    11641 tgcggcggct ggcttggcgt tcgtttgctt aaaggcaaag cgctattccg ccagtttagc
    11701 ggatgattca tgatgtgaat aatttcgcgc tggtttttaa aacggcgcgt acttttttag
    11761 tcgcacaaat tgataactcc ttgattttta gtagcacaaa tcattaaaaa atacacaaca
    11821 cgtaaggttt tataacagtt attatttg
//
LOCUS       DAJVBX010000152        11834 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.152, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000152 DAJVBX010000000
VERSION     DAJVBX010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 11834)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11834)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11834
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.152"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            7..1038
                     /gene="asrA"
                     /locus_tag="OPV72_003356"
     CDS             7..1038
                     /gene="asrA"
                     /locus_tag="OPV72_003356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015461495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit A"
                     /protein_id="HCR9915568.1"
                     /translation="MTPDEFSLLIQRLNKKWRVFAPSAEFRGGRFSDTDNIIYQRISG
                     WRDLIWHEKSHMSPNTIIAPITETLFYFDKNTIQIAETDTSPIIIFARACDINAMSRL
                     DYMYLSNGNNSDYSYQLLREHIRFVLIECEESFENCFCVSMGTNKTDCYSAAMRFSDE
                     GALVSIRDPFIEAAIQGLGQEADYTPSFVSENRETVVTPDSVCRDPQKIRDILTRHPL
                     WDAYDSRCISCGRCTTGCPTCTCYSVFDVAYDENPQRGERRRQWASCMVPGFSDMAGG
                     HGFREKPGERLRYRALHKVNDYKARNGIEHMCVGCGRCDDRCPQYIKFSLIINKMTAA
                     VRQALAEEA"
     gene            1042..1860
                     /gene="asrB"
                     /locus_tag="OPV72_003357"
     CDS             1042..1860
                     /gene="asrB"
                     /locus_tag="OPV72_003357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit B"
                     /protein_id="HCR9915569.1"
                     /translation="MSHCSCHDKPQHSLLPAAYRILSITRHTPLEWNFRVAVDFPAHW
                     GQFVEVSLPRVGEAPISVSDYGDGWIDLLIRNVGKVTSALFTLKEGDNVWLRGCYGNG
                     YPVDTLRHKPLLVVAGGTGVAPVKGLMRYFVENPQEIGQLDMILGYKNRDCVLYKEEM
                     ATWHGKHNLVLTLDEGEADDRYQIGRVTDRLADMTLSDIDTMQAIVVGPPIMITFTVK
                     MLLQKGLKPEQIWVDYERRMACSVGKCGHCRMGEVYVCTDGPIFNYAVAQRFAD"
     gene            1871..2884
                     /gene="asrC"
                     /locus_tag="OPV72_003358"
     CDS             1871..2884
                     /gene="asrC"
                     /locus_tag="OPV72_003358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite reductase subunit C"
                     /protein_id="HCR9915570.1"
                     /translation="MSIDIDIIKARAKNEYRLSKVRGEAMISVRIPGGILPAHLLTVA
                     RDIAETWGNGQIHLTTRQKLAMPGIRYEDIDNVNAALEPFLREIEIELCDVQVEDTKA
                     GYLAIGGRNIVACQGNRICQKANTDTTGLSRRLEKLVYPSPYHLKTVIVGCPNDCAKA
                     SMADLGIIGVAKMRFTADRCIGCGACVKACSHHAVGCLALKNGKAVKEESACIGCGEC
                     VLACPTLAWQRKPDQLWQVRLGGRTSKKTPRVGKLFLNWVTEDVIKQVIVNLYEFEKE
                     MLGGKPIYLHMGHLIDKGGYLRFKERVLRGVQLNPEAMVAERIYWAEDESVARMHLKP
                     AGH"
     gene            complement(2885..3870)
                     /locus_tag="OPV72_003359"
                     /pseudo
     CDS             complement(2885..3870)
                     /locus_tag="OPV72_003359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461486.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nickel/cobalt transporter"
     gene            complement(3861..4499)
                     /locus_tag="OPV72_003360"
     CDS             complement(3861..4499)
                     /locus_tag="OPV72_003360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1007 family protein"
                     /protein_id="HCR9915571.1"
                     /translation="MKPVKRSALILFLAVLSFVAAAHPHSFIRLQTQVVSENEQFVAL
                     KMRWTMDALTSADLLYDAGNAAPGSEIWKKLAAEVMANVLGQHYFTEVWRNGAKVKFK
                     NRPTEYGMTRDAHQAVLTFTLPLAEPQPLSGQTYTFSTFDPSYYVDMHYDQDSDITMP
                     EPLREKCRIQVYTPAPGEETLRFAQSLDKEDAPPEDMDLGKQFAQTVTLQCQ"
     gene            4625..5902
                     /gene="csiE"
                     /locus_tag="OPV72_003361"
     CDS             4625..5902
                     /gene="csiE"
                     /locus_tag="OPV72_003361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stationary phase inducible protein CsiE"
                     /protein_id="HCR9915572.1"
                     /translation="MMPTIAPPSVLSAPQRRCQVLLTLFQPEPIATVEIFSALNGVDD
                     DTAREDITDTSLEIQRYHRLAITTCQNGCYRIEGTALDQRLCLLHWLRRGLRLCPTFV
                     TQQFTPALKNALKQRGIARPLYDDINLHALINLCARRLQKPFEHRDVQFLRLFLQYCL
                     LQHHAGITPEFNPVQQIWAQSCAEYPLAQEIGRHWQRHVMQAAPLNEALFMALLFSMI
                     RLPDPIRDTHQRAQQLRLEVARLVLRFREKGNVRFSDEQGLNDQLYVHLAQALNRSLF
                     TIGIDNTLPEEFNRLYPRLVRTTREALAGFEAEYGIHFSEEETGLVAVIFGAWLMQDN
                     DLHERQIVLLADKNDALETHIEQQLRELTLLPLNIRRISLQAFQKEGCPRGVALIVTP
                     YATPLPLFSPPLIHADRALTEHQQQQIRKILES"
     gene            complement(5897..7036)
                     /locus_tag="OPV72_003362"
     CDS             complement(5897..7036)
                     /locus_tag="OPV72_003362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phenylpropionate MFS transporter"
                     /protein_id="HCR9915573.1"
                     /translation="MALHSTRWLALSYFTYFFSYGIFLPFWSVWLKGLGLTPETIGLL
                     LGVGLVARFLGSLLIAPRVSDPSRLISALRVLALLTLVFALAFWAGTHVAWLMVVMVG
                     FNLFFSPLVPLTDALANTWQKQITLDYGRVRLWGSIAFVIGSALTGKLVSLYDYQAIL
                     ALLTLGVASMLLGMLLRPSVPPQGESRQQESAGWPAWRTLVAQSWRFLACVCLLQGAH
                     AAYYGFSAIYWQGAGYSASAVGYLWSLGVVAEVIIFALSKKLFRRFSARDLLLLSAVC
                     GVVRWGLMGWSTALPWLIVIQILHCGTFTVCHLAAMRYIAARQGSEVIRLQAVYSAVA
                     MGGSIAIMTVFAGFLYQHLGGGVFWIMALVALPAIFLRPKVVAAS"
     gene            complement(7221..8474)
                     /locus_tag="OPV72_003363"
     CDS             complement(7221..8474)
                     /locus_tag="OPV72_003363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019077397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HCR9915574.1"
                     /translation="MLKREMNIADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVM
                     QAQGSQLTNKYAEGYPGKRYYGGCEYVDVVEQLAIDRAKELFGADYANVQPHSGSQAN
                     FAVYTALLQPGDTVLGMNLAQGGHLTHGSPVNFSGKLYNIVPYGIDESGKIDYDEMAK
                     LAKEHKPKMIIGGFSAYSGVVDWAKMREIADSIGAYLFVDMAHVAGLIAAGVYPNPVP
                     HAHVVTTTTHKTLAGPRGGLILAKGGDEELYKKLNSAVFPSAQGGPLMHVIAGKAVAL
                     KEAMEPEFKVYQQQVAKNAKAMVEVFLNRGYKVVSGGTENHLFLLDLVDKNLTGKEAD
                     AALGRANITVNKNSVPNDPKSPFVTSGIRIGSPAVTRRGFKEAEVKELAGWMCDVLDN
                     INDEATIERVKAKVLDICARFPVYA"
     gene            8799..9989
                     /gene="hmpA"
                     /locus_tag="OPV72_003364"
     CDS             8799..9989
                     /gene="hmpA"
                     /locus_tag="OPV72_003364"
                     /EC_number="1.14.12.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NO-inducible flavohemoprotein"
                     /protein_id="HCR9915575.1"
                     /translation="MLDAQTIATVKATIPLLVETGPKLTAHFYDRMFTHNPELKEIFN
                     MSNQRNGDQREALFNAIAAYASNIENLPALLPAVEKIAQKHTSFQIKPEQYNIVGTHL
                     LATLDEMFNPGQEVLDAWGKAYGVLANVFIHREAEIYHENASKDGGWEGTRPFRIVAK
                     TPRSALITSFEFEPVDGGTVAEYRPGQYLGVWLKPEGFAHQEIRQYSLTRKPDGKGYR
                     IAVKREDGGQVSNWLHHHANVGDVVHLAAPAGDFFMNVAADTPVSLISAGVGQTPMLA
                     MLDTLAKEQHTAQVNWFHAAENGDVHAFADEVSELGRTLPRFTAHTWYREPTEADRAQ
                     RVFDSEGLMDLSKLEAAISDPAMQFYLCGPVGFMQFAAKQLVSLGVNNENIHYECFGP
                     HKVL"
     gene            10170..11714
                     /gene="cadC"
                     /locus_tag="OPV72_003365"
     CDS             10170..11714
                     /gene="cadC"
                     /locus_tag="OPV72_003365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine decarboxylation/transport transcriptional
                     activator CadC"
                     /protein_id="HCR9915576.1"
                     /translation="MQQPVVRIGEWLVTPSVNQISRQGRQITLEPRLIDLLMYFAHHP
                     DEVLSRDNIIDHVWMRTIVTNHVVTQSISELRKSLRDGGDSNAEYIVTVPKRGYKLTA
                     PVIWCEENSDEIDNLSTSPPPPIAATNAEPTEGVPAAAPVPPASLQTPTKKAKKPRIA
                     AFWTWVMFLLSLATLVVFIVMSVVDHNAAVTKTRLLLNPRDIDVRFEGGNSCNNWVSQ
                     ESYAIGLGGLITDLLNTYSTFMVHDKTNYRVNEPSNSGKTLTIQFVNQRHYRAQQCFM
                     SVVLIDNADGSTMLDKRYFVTNTNQLSIQDDLFNSLSFVLTQPWPNRMREQLALFRTP
                     QNTALMRFYEARQLILSGDAQALSKAGDILNGIIKETPDFNYAYEYKVLVDVLRQSQQ
                     PFDKEQVAALNEEFKKIDQIPGVEKTSVYYKIKTVDLLGKGDIDAAYEEINKSIELEM
                     SWFNYVLLGKVYEMKGENRLAADAYLTAFNLRPGENTLYWIENGVFQTSVQKIVPYLN
                     SFLAED"
BASE COUNT         2866 a         3290 c         3059 g         2619 t
ORIGIN      
        1 atcaaaatta cgcctgacga gtttagtctg cttatccagc gattaaacaa aaaatggcgc
       61 gtgtttgccc cgtccgcaga gtttcgcggc gggcgttttt ccgacactga caacattatt
      121 tatcaacgga ttagcggctg gcgcgatctc atctggcacg agaaatcgca catgtcgccg
      181 aataccatta tcgcccctat caccgaaacg ctcttttatt tcgataaaaa caccattcaa
      241 attgccgaga cagacacctc cccgataatc atctttgccc gcgcctgcga cattaacgcc
      301 atgtcgcggc tggattatat gtatttatca aatgggaata attccgatta cagttatcaa
      361 ctgctacggg agcatattcg tttcgtcctt attgagtgtg aagaaagctt cgaaaattgt
      421 ttctgcgtct caatgggtac taataaaact gactgttata gcgccgccat gcgttttagc
      481 gatgagggcg cgcttgtgag catccgcgat ccctttatcg aggcggcgat acaaggactg
      541 gggcaggagg ctgactatac cccctctttc gtcagcgaaa accgggaaac cgtcgtcacg
      601 ccggacagcg tttgccgcga tccgcaaaaa attcgcgaca ttctcactcg ccatccgcta
      661 tgggacgcct acgacagccg ctgcatcagt tgtggccgct gtactaccgg gtgcccaacc
      721 tgtacctgct atagcgtctt tgacgtcgcc tatgatgaaa atccgcagcg cggcgaacgc
      781 cgtcgccagt gggcaagctg catggtgccg ggctttagcg acatggccgg cggtcatggt
      841 tttcgcgaaa aacccggcga gcgtctgcgc taccgcgccc tgcataaggt caatgactac
      901 aaagcgcgca acggcattga acatatgtgc gtcggctgcg gccgctgcga cgatcgctgc
      961 ccgcaataca tcaaattttc tttgattatt aacaaaatga ccgctgccgt tcggcaggcg
     1021 ctggcagagg aggcataacg catgtcacat tgttcctgtc atgataaacc gcagcacagt
     1081 ttgctgcctg cggcgtaccg catcctcagt attactcgcc acacgccgct ggagtggaat
     1141 ttccgcgtgg ccgtcgattt tcccgcgcac tgggggcaat ttgttgaggt gtcgctgccg
     1201 cgcgtcggcg aagcgcccat ctccgtttcc gactacggcg atggctggat agatctgctg
     1261 attcgtaatg tcggaaaagt gaccagcgcc ctctttacgc tgaaagaagg cgacaacgtg
     1321 tggctacgcg gctgctatgg caatggctat ccggtcgata ctctgcgcca taaaccctta
     1381 ctggttgtcg caggcggcac gggcgtcgcg ccggtgaaag gcttaatgcg ctatttcgtt
     1441 gagaatcccc aggaaattgg tcaactggat atgattctcg gctataaaaa tcgcgattgc
     1501 gtgctgtaca aagaagaaat ggcgacgtgg cacggcaaac ataatctggt gctcacgctg
     1561 gatgaaggcg aggctgatga ccgttaccag attggtcggg tgaccgatcg gcttgccgac
     1621 atgacgctta gcgatatcga caccatgcag gccatcgtcg ttgggccgcc aataatgatt
     1681 acctttaccg taaaaatgct gctgcaaaaa gggctcaagc cggagcaaat ttgggtggac
     1741 tacgaacgcc ggatggcctg ctccgtcggg aagtgcggcc actgccgtat gggcgaagtg
     1801 tatgtctgca ccgacggccc gatatttaac tacgccgtcg cgcaacgttt tgccgattaa
     1861 ggagaacatc atgagcattg atattgatat cattaaagcc cgtgcgaaaa acgaatatcg
     1921 cctatcaaaa gtgcgcggcg aagccatgat cagcgtccgc attcccggcg gtattttgcc
     1981 cgcgcatttg ctaacggtgg cgcgtgacat cgccgaaacc tggggcaacg gacaaattca
     2041 cctcactacc cgccagaagc tggcgatgcc gggtatccgt tacgaagata tcgacaacgt
     2101 gaacgctgcg ctggagccat ttcttcgcga gattgaaata gaactgtgcg acgtccaggt
     2161 tgaggatacc aaagcgggct atctcgctat tggcgggcga aatattgtcg cctgtcaggg
     2221 gaaccgcatt tgccagaaag ccaacactga cacgaccggt ctgtcccgtc gtcttgaaaa
     2281 actggtctat cccagccctt atcatctcaa aacggtcatt gttggctgcc cgaatgattg
     2341 cgcgaaggcg tcaatggccg atctgggaat tattggcgtg gcgaaaatgc gcttcactgc
     2401 cgatcgctgt atcggttgcg gcgcctgcgt gaaggcctgt agtcaccacg cggtaggctg
     2461 cctggcgctg aagaacggca aagcggtcaa agaagagtcc gcctgtatcg gctgcggcga
     2521 gtgcgtgctg gcctgtccga cgctggcctg gcaacgtaag ccggatcagc tctggcaagt
     2581 ccgtctgggc ggacgcacca gtaaaaagac gccgcgcgtc ggcaagctct tcctcaactg
     2641 ggtgactgaa gatgtgataa agcaggtgat cgttaacctg tatgaatttg aaaaagagat
     2701 gctcggcgga aaaccgatct atctacatat gggccatctg atcgacaaag gcggctatct
     2761 gcgttttaaa gaacgggtac tgcgcggcgt tcagctcaat ccggaagcga tggtcgccga
     2821 acgcatttac tgggccgaag acgaatccgt cgcgcggatg catctcaaac ccgccgggca
     2881 ctagtcaacc acgccatggc cgcagcccgc ccacaggctg cggcacgcta aaccacatga
     2941 ccagcgccgc gacaagcagt atgacccctc cggccagcgc cagcgttgac cagcctacct
     3001 gccgccataa cgccggcgct ttgtttccac tgagcttcac cgccagagca cgaaaagtgt
     3061 gtaccagcag cgccagcgaa gtaatcgtta gcgaggttcc cgccgccatt gccagtaccg
     3121 acgccattcc ccagctaaaa acgccaatca ctttactgaa taacagcacc attatcgctc
     3181 cggaacaggg ccgcatcccc atagacagta cgatcatgag tcgcgcgcgc cagtcatcgc
     3241 cgctatgcaa ttgttcctgc gtcggtagat gctgatgtcc gcagccgcat ttttcatggt
     3301 gaacatggcg cggcgtaaaa gcgataaaga caggtttacg tagcagcgcg cgtaaccttt
     3361 ttatggcccg ccagcacagc aagatgccca gcccgccaac taacgcatag ctcccctttt
     3421 ccagccagaa accgctcaga tggagctgcc tggccggaag ttgcaatacg gtcagcacgc
     3481 ccaccaccaa cccgatagcc acgaccccct gcaataacgc ggcggcgagg gttaacacga
     3541 tacttgattt cagcttcgaa ggatgcgtcg ccagccatgt cgcgatcacc actttgccgt
     3601 gtcccggccc cacgcatgaa gcacgccata cataaaactc agcagaagca acgatccgcc
     3661 cgcccgctca ggatgcgtcg ccaccgcatt aagcagcgcg ctcaactgct gattcacgtc
     3721 ccgctgccaa agagcgcttt tcagcatcac ctgcggccag gcctgccata tccacagacc
     3781 gccaaccagc atcagcagca ggaataacgc caatggccac agcgagagcc agcgtcgccc
     3841 cggagtgcgt tgagaaaaaa ttactgacat tgcaaggtca ccgtttgggc aaactgttta
     3901 cctaaatcca tatcctccgg cggcgcgtcc tctttatcca gcgactgggc gaaacgtagc
     3961 gtctcttcgc cgggcgcagg agtataaacc tgaatccgac acttttcgcg cagcggttcc
     4021 ggcatcgtga tatcgctgtc ctggtcataa tgcatatcga cataataaga gggatcaaac
     4081 gttgaaaagg tataagtctg gccgcttaac ggctgcggtt cagccagcgg cagcgtaaag
     4141 gtcaataccg cctgatgcgc gtcacgcgtc ataccgtatt ctgtcggcct gtttttaaac
     4201 ttcactttcg cgccattgcg ccacacttct gtaaagtagt gctgcccaag tacgttagcc
     4261 atcacttccg ccgccaactt tttccatatt tctgaacccg gcgccgcgtt tccggcgtca
     4321 tacagcagat cggcggacgt cagcgcgtcc attgtccagc gcatttttaa cgccacaaat
     4381 tgctcatttt cactgaccac ctgcgtttgc agacggatga agctgtgcgg atgcgccgcc
     4441 gccacgaaag ataaaacggc gagaaatagt attaaggcgc tgcgtttcac tggcttcatc
     4501 tgttcctcgc gataaaaatt ctgtgacact cctcagcatt cctggcctaa aagcacactt
     4561 atcacatttt tcacatgcaa actttagcta tccttaccag ataaactaac gggagacctg
     4621 acagatgatg ccgacaattg ccccaccatc tgtactttcc gctccccagc gccgctgtca
     4681 ggtattgctg acgcttttcc agccggagcc aattgccacg gtggaaatct tcagcgcgct
     4741 taatggcgtt gatgatgata ctgcccgtga ggatatcact gacacaagcc tggagatcca
     4801 gcgctatcat cgccttgcca tcacaacatg ccagaacggt tgctatcgga tcgaaggtac
     4861 agcactcgat cagcgccttt gccttttaca ctggctcagg cgcggcctgc gtttatgccc
     4921 gaccttcgtc acgcaacagt ttaccccggc cttaaaaaac gcgctaaagc agcgcggtat
     4981 cgcgcgtccg ctgtatgacg atattaatct gcacgcgctc atcaatctgt gcgcccgccg
     5041 gttgcaaaaa ccatttgaac atcgcgacgt gcagttcctg cgtctctttt tacagtattg
     5101 tctgctacaa caccatgccg gcatcacccc ggaattcaat cctgtacagc agatttgggc
     5161 gcagtcgtgt gcggaatatc cactcgccca ggaaattggt cgtcactggc agcgccacgt
     5221 gatgcaggcc gcaccgctca atgaagcgct gtttatggcg ttactgtttt caatgattcg
     5281 cctccccgac ccgattcgcg acacgcatca acgggcgcag caactgcgac tggaggtggc
     5341 gcggctggtg ctgcgctttc gagaaaaagg gaacgtacgc ttcagcgacg aacaagggct
     5401 taacgatcag ctgtatgtcc atctcgccca ggcgctgaac cgaagtttat tcacgattgg
     5461 catcgataat acgcttccgg aagagttcaa ccgtctttat ccgcgtctgg ttcgcaccac
     5521 acgtgaggcg ctcgccgggt ttgaagccga atatggtatc cacttttccg aggaagagac
     5581 ggggctggtg gcagtgattt tcggcgcctg gctgatgcag gataacgatt tgcatgagag
     5641 acagatcgta ttgttagcgg ataaaaatga tgcgctggag acgcatattg agcagcaact
     5701 gcgtgaactg accctattgc cgctgaatat cagacggata tcgctccagg cgtttcaaaa
     5761 agagggatgc ccgcgcggcg tagcgctgat tgttacccct tacgccacgc cgctaccgct
     5821 cttctcaccg ccattaattc atgcggatcg cgccctcaca gagcaccaac agcagcagat
     5881 ccgcaagatc ctggaatcat gacgcggcaa ccactttggg ccgaaggaag atagcgggca
     5941 atgccaccag cgccataatc cagaatacgc cgccgcccag atgttgatac agaaaaccgg
     6001 caaataccgt cataatcgcg atactgccgc ccatcgccac agcggaatag acggcctgca
     6061 aacgaatcac ctcgcttccc tgacgcgcag cgatatagcg catagcggcc agatggcaaa
     6121 cggtaaacgt gccacagtgc aggatttgta tcacaatcag ccacggcaac gccgtactcc
     6181 agcccatcag tccccagcgt accacgccgc acacagcaga aagcaacagc aagtcgcggg
     6241 cgctaaaccg gcggaatagc tttttactca gggcaaaaat gatcacttcc gccaccacgc
     6301 ccaacgacca taaatagccg accgccgatg ctgaatagcc agccccctgc cagtagatgg
     6361 cgctaaaacc gtagtaggcg gcgtgcgccc cttgcagcaa acagacgcag gcgagaaaac
     6421 gccaactttg tgccaccagc gtacgccagg cgggccagcc tgcgctctcc tgctgacggc
     6481 tttccccttg cggcggcacg ctgggacgta acaacatacc cagcaacatc gaggcgacgc
     6541 cgagcgtcag tagcgccaga atcgcctggt aatcgtataa actcaccagc ttaccggtca
     6601 gcgccgaccc tatcacgaag gcgatggacc cccacagccg cacccgacca tagtccaggg
     6661 taatttgctt ttgccaggta ttggccagcg catcggtcag cggcaccagt ggtgaaaaga
     6721 agaggttaaa cccaaccatc accaccatta gccacgcgac atgcgttcct gcccaaaatg
     6781 ccagcgcaaa taccagcgtc agcaatgcca ggacgcgcag cgcggagatc aaccgcgaag
     6841 gatcgcttac gcgaggcgca atgagcagac taccgagaaa acgcgcgacc agacccacgc
     6901 ccagcagaag accgatggtt tccggcgtta gcccaagacc tttgagccag acgctccaga
     6961 agggcagaaa aataccgtaa ctaaagaagt aggtgaaata actgagcgcc agccagcgcg
     7021 tggaatgcaa tgccatgatt ccctcccgtt tggaggcgat agtctggcgg taaacggttg
     7081 cgctggcaag ggtaacaggc ggagggagaa gttcaaacgg caacgccgcc ggataatgac
     7141 ttccggcggc gtcacgttat ggcgcataag taatgcccga cagacgcagc gccatcgggc
     7201 catttacaca acacaaacgc ttacgcgtaa accgggaagc gggcgcagat atccagcact
     7261 ttcgctttca cgcgttcaat ggtggcttca tcattgatgt tgtccagcac gtcacacatc
     7321 cagccagcca gctctttcac ttccgcttct ttgaagccgc gacgagtaac cgccggagaa
     7381 ccaatacgga taccggaggt cacgaacggg ctcttcggat cgttcggcac gctgtttttg
     7441 ttcacggtga tgttagcacg gcccagcgcg gcgtcagctt ctttaccggt caggttttta
     7501 tccaccaggt ccagcaggaa caggtggttc tcagtgccgc cagacaccac tttgtagccg
     7561 cggttcagga acacttccac catcgctttg gcgtttttcg ccacctgctg ctggtaaact
     7621 ttgaactccg gctccatcgc ttctttcagc gctaccgctt tacccgcgat cacgtgcatc
     7681 agcgggccgc cctgcgcgct tgggaagacg gcggagttca gttttttgta cagctcttcg
     7741 tcgccgcctt tcgccaggat caggccgccg cgcggacccg ccagggtttt gtgggtggtg
     7801 gtggtgacaa cgtgagcgtg cggaaccggg ttcgggtaaa cgcctgcggc aatcaggccc
     7861 gccacgtgcg ccatgtcgac aaacaggtat gcgccgatgc tgtcagcgat ttcacgcatt
     7921 tttgcccagt caaccacacc ggagtaggca gagaagccac cgataatcat cttcggcttg
     7981 tgctctttgg ccagcttcgc catctcgtca tagtcaattt taccggactc atcgataccg
     8041 taaggtacga tgttgtacag tttaccggag aagttaaccg gggagccgtg agtcaggtgg
     8101 ccgccctgcg ccaggttcat acccagaacg gtatcgcccg gctgcagcag cgcggtgtaa
     8161 acagcgaagt tagcctgaga accggagtgc ggctgcacgt tagcgtagtc ggcgccgaac
     8221 agttctttcg cgcggtcgat agccagctgc tctacgacat caacgtattc gcaaccgccg
     8281 tagtagcgct tgcccggata tccttcagcg tatttgttgg tcagctgaga cccctgcgcc
     8341 tgcatcacgc gcgggctggt gtagttttcg gaggcgatca gttcgatgtg ctcttcctga
     8401 cgtacttttt cctgctccat agcctgccac aattcggcat cataatcggc aatgttcatt
     8461 tcacgcttta acatccgcat ctcctgactc agctaacaat aaaatttgtg cctgaaaagg
     8521 cagtccgtgg gacttcggcc aacagtataa ccgaatcatt cttcgataac aggtcttgac
     8581 aaaggttttt acgcaaacga ttacctatgc gtcagataag ggtttcctga acgagagcct
     8641 gacgaatttc aacggatttc ttttcagctt tgtgatgcag atttttcacg ttgttacctc
     8701 cataacgtaa agcagagaag atccatttac aatgcaaggg tatttttata agatgcattt
     8761 gatatacatt attagatttt cacataaagg aagcacgtat gcttgacgca caaaccatcg
     8821 ctacagtaaa ggccaccatt cccctgctgg ttgaaacagg accgaaactg accgcccact
     8881 tctacgaccg tatgtttacg cataacccgg agctcaaaga aatcttcaat atgagcaacc
     8941 agcgtaacgg tgatcagcgc gaagccctgt ttaatgctat cgcggcctac gccagcaata
     9001 tcgaaaattt accggcgttg ctgccggcgg tagaaaaaat cgcgcagaag cacaccagct
     9061 tccagattaa gccggagcag tacaacatcg tcgggacgca tctgctggcg acgctggatg
     9121 aaatgttcaa cccgggccag gaagtgctgg acgcatgggg taaagcctat ggcgtactgg
     9181 ctaacgtctt tattcatcgg gaagccgaga tttatcacga gaacgccagc aaagacggcg
     9241 gctgggaagg cacgcgcccc ttccgcatcg ttgcgaaaac cccgcgtagc gcactgatca
     9301 ccagctttga gtttgaaccg gtcgacggcg gtacggtggc ggaataccgt cccgggcagt
     9361 atctgggcgt ctggctgaag ccggaaggtt ttgcgcatca ggagatccgc caatattcac
     9421 tgacccgtaa acccgatggc aaagggtacc gtattgccgt gaagcgtgaa gacggcggcc
     9481 aggtatcaaa ctggttacac catcacgcca acgtaggcga tgtggtgcat ctggctgcgc
     9541 cggcaggtga cttctttatg aatgtcgccg ctgatacccc cgtttcgctg atttccgctg
     9601 gcgtcggcca gacgccgatg ttggcgatgc tcgatacgct ggcgaaagaa cagcataccg
     9661 cgcaggtgaa ctggttccac gcggcggaga acggcgacgt ccatgcgttt gccgacgaag
     9721 tgagcgagct gggccgtaca ctgccgcgtt tcactgccca tacctggtac cgcgagccaa
     9781 ccgaggccga tcgcgcccaa cgcgtctttg acagcgaagg gctgatggat ttaagcaaac
     9841 tggaagccgc gatcagcgat ccggcaatgc agttctatct ttgcggcccg gtaggcttta
     9901 tgcagtttgc cgcaaaacaa ctggtttcac ttggcgtgaa taacgaaaac attcattacg
     9961 aatgcttcgg cccgcataaa gtgctgtaat tgcaagaaat ccgctgaaaa aacgggcgtt
    10021 atcgttaagg cgaacgcccg ttttcctccc cgttctcctg cttattgcgc tgctttttat
    10081 gcctttcttt tacaaaaaag gggaataaaa aagtctgtgc aaatcgtgtt attattaacg
    10141 tttgacttag ctcgttaggg catcttttta tgcagcaacc tgttgtacgc attggagagt
    10201 ggctggttac accttctgtt aatcagatca gtcgtcaggg acgccagatt actcttgaac
    10261 cacggctgat cgatcttctg atgtattttg cgcatcatcc ggatgaagtg ttaagccggg
    10321 ataacattat tgatcatgtc tggatgcgca ccatcgtgac caaccatgtt gtcacccaaa
    10381 gcatttctga actacgcaaa tcattaagag atggcggaga cagcaatgct gaatacatcg
    10441 ttaccgtacc taaacgcggc tataagctga cggcgccggt tatctggtgc gaagaaaata
    10501 gcgatgagat cgataattta tcaacgtcgc cgccgccgcc gatcgcagcg acgaatgcag
    10561 aaccgacaga gggggttcct gccgctgcgc ctgtgccgcc cgcctctttg caaacgccga
    10621 ctaaaaaggc gaaaaagccg cgtatcgccg ctttctggac gtgggtgatg ttcctgctct
    10681 cgctggcgac gctggtggtg tttatcgtga tgtcggtggt agatcataat gccgcggtaa
    10741 caaaaacgcg gttattactt aacccacgag atatagatgt tcgttttgaa ggcggcaatt
    10801 cctgtaataa ctgggtctcg caggagtcct acgccatcgg tctgggcggc ttaatcaccg
    10861 acctgctgaa cacctactcg acctttatgg tgcacgataa aaccaattac cgggtcaatg
    10921 agccaagcaa ctccggtaag acgttaacca ttcagtttgt caatcagcgc cactatcggg
    10981 cgcagcagtg ctttatgtct gtggtgctca ttgataacgc cgatggttca accatgctgg
    11041 ataagcgtta tttcgtcacc aatactaacc agttgtccat ccaggatgat ctgtttaata
    11101 gcctgtcttt cgttttaaca cagccctggc ctaatcgtat gcgagaacaa ctggccctgt
    11161 tcagaacgcc gcaaaatacc gcgctgatgc gtttttatga ggcgcgccag cttattctga
    11221 gcggcgatgc gcaggcgcta agtaaagccg gcgatattct gaatggcatt attaaggaaa
    11281 cgcctgattt caactatgcc tatgaatata aagtgctggt agatgtatta cggcaatcac
    11341 aacagccgtt tgataaagaa caagtggctg cgctgaacga agagtttaaa aaaatagatc
    11401 aaattccggg cgttgagaaa acgtctgttt attataaaat caagaccgtt gatcttttgg
    11461 gcaaaggtga tatcgatgca gcgtatgagg aaatcaataa aagcatcgag cttgaaatgt
    11521 cgtggtttaa ctatgtcctg ttggggaaag tttacgaaat gaaaggtgag aatcgtctgg
    11581 ccgctgatgc ctatctgacc gcctttaatt tacgtccagg tgaaaatacg ctgtactgga
    11641 tcgagaacgg cgtatttcag acatccgttc agaaaattgt cccttatctg aatagttttc
    11701 tggcagaaga ttaaatttaa cgctgaacca tgacaaataa aagcgaaaag atattaaatt
    11761 tttcgctttt attttgtgaa aaatatgttg caaaaaatag cttatgttaa ttttggcaac
    11821 atattcatcg caaa
//
LOCUS       DAJVBX010000153        11556 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.153, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000153 DAJVBX010000000
VERSION     DAJVBX010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 11556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11556
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.153"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            493..729
                     /locus_tag="OPV72_003366"
                     /pseudo
     CDS             493..729
                     /locus_tag="OPV72_003366"
                     /inference="COORDINATES: protein motif:HMM:NF025063.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            871..1338
                     /locus_tag="OPV72_003367"
     CDS             871..1338
                     /locus_tag="OPV72_003367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCR9915577.1"
                     /translation="MKIRRFSNGDEISLFRVFFSSVHTIASHYYTREQIDAWAPADID
                     LERWANHIKELQPFVVELDGEIAGYADVQPNGYIDHFFVSGTYSRQGVGTLLMNCIHE
                     EARQRGISELTSNVSKAAEVFFLRHGFHIVERGFPICRGVTLQNALMRKCLAK"
     gene            1516..1803
                     /locus_tag="OPV72_003368"
     CDS             1516..1803
                     /locus_tag="OPV72_003368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1778 domain-containing protein"
                     /protein_id="HCR9915578.1"
                     /translation="MLYKGCLMKSDVQLNLRAKESQRALIDAAAEILHKSRTDFILET
                     ACRAAENVILDRRVFNFNDEQYEEFINLLDAPVADDPVIEKLLARKPQWDV"
     gene            1791..2276
                     /locus_tag="OPV72_003369"
     CDS             1791..2276
                     /locus_tag="OPV72_003369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCR9915579.1"
                     /translation="MGRVTAPEPLSAFHQVAEFVSGEAVLDDWLKQKGLKNQALGAAR
                     TFVVCKKDTKQVAGFYSLATGSVNHTEATGNLRRNMPDPIPVIILARLAVDLSFHGKG
                     LGADLLHDAVLRCYRVAENIGVRAIMVHALTEDAKNFYIHHGFKSSQTQQRTLFLRLP
                     Q"
     gene            complement(2647..3186)
                     /gene="cueP"
                     /locus_tag="OPV72_003370"
     CDS             complement(2647..3186)
                     /gene="cueP"
                     /locus_tag="OPV72_003370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-binding periplasmic metallochaperone
                     CueP"
                     /protein_id="HCR9915580.1"
                     /translation="MSKSSWLLLLGLCASGSALAASSESAFLAQHGLAGKTVEQIVDT
                     IDQTPQSRPLPYSASITSTELKLSDGEQIYTLPLGDKFYLSFAPYEWRTHPCFNHSLS
                     GCQGEMPNKPFTVKVTDSKGAVIVQKEMQSYRNGFIGVWLPRNMEGTLEVSYNGKTAS
                     HAIATRDDSQTCLTELPLR"
     gene            complement(3362..3574)
                     /gene="cspA"
                     /locus_tag="OPV72_003371"
     CDS             complement(3362..3574)
                     /gene="cspA"
                     /locus_tag="OPV72_003371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone/antiterminator CspA"
                     /protein_id="HCR9915581.1"
                     /translation="MSGKMTGIVKWFNADKGFGFITPDDGSKDVFVHFSAIQNDGYKS
                     LDEGQKVSFTIESGAKGPAAGNVTSL"
     gene            complement(3787..4152)
                     /locus_tag="OPV72_003372"
     CDS             complement(3787..4152)
                     /locus_tag="OPV72_003372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator"
                     /protein_id="HCR9915582.1"
                     /translation="MEYKDPMFELLSSLEQIVFKDETRKITLTQKPNPFTEFEQLRRG
                     TGLKTDEFARALGVTVAMVQEWESKREKPTPAELKLMRLIQANPRLSKQLMEQFLPLS
                     VLTVLRKGRFPRPITGLEK"
     gene            4591..5301
                     /locus_tag="OPV72_003373"
     CDS             4591..5301
                     /locus_tag="OPV72_003373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3053 domain-containing protein"
                     /protein_id="HCR9915583.1"
                     /translation="MATGKSCSRWFAPVVALLMVFSLSGCFDKEGDQRKAFVDFLQNT
                     AMRSGERLPTLTADQKKQFGPFVSDYAILYGYSQQVNQAMDSGLRPVVDSVNAIRVPQ
                     DYMTQREPLRQANGSLGVLAQQLQNAKLQADAAHGALKQADDLKPVFDQVYKKVVTVP
                     ADALQPLIPAAQIFTQQLVQVGDYIAQQGEQVSFVANGIQFPTSQQASQYNALIGPLA
                     SQHQAFNQAWTAAVNATQ"
     gene            complement(5351..6325)
                     /gene="ghrB"
                     /locus_tag="OPV72_003374"
     CDS             complement(5351..6325)
                     /gene="ghrB"
                     /locus_tag="OPV72_003374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate/hydroxypyruvate reductase GhrB"
                     /protein_id="HCR9915584.1"
                     /translation="MKPSIILYKTLPDDLLHRLEAHFTVTQVPNLHPETVARHAQAFA
                     SAQGLLGTSETVNRALLEKMPALRAASTISVGYDNVEVDALTARKIVLMHTPAVLTET
                     VADTVMALMLATARRVVDVAERVKAGEWTESIGPAWFGVDVHHKTLGIVGMGRIGMAL
                     AQRAHFGFTMPVLYHARRRHQEAEDRFNARYCDLDTLLQEADFVCVILPLTAETRHLF
                     GATQFARMKSSAIFINAGRGPVVDENALIAALQNGEIYAAGLDVFEQEPLSVDSPLLN
                     MSNVVAVPHIGSATHETRYNMMACAVDNLIDALQGKIEKNCVNPQAAG"
     gene            complement(6544..7206)
                     /locus_tag="OPV72_003375"
     CDS             complement(6544..7206)
                     /locus_tag="OPV72_003375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family lipoprotein"
                     /protein_id="HCR9915585.1"
                     /translation="MKKRVFVIAAIVSGALAVSGCTTNPYTGEREAGKSGIGAGIGSL
                     VGAGIGALSSSKKDRGKGALIGAAAGAALGGGVGYYMDVQEAKLRDKMRGTGVSVTRS
                     GDNIILNMPNNVTFDSSSATLKPAGANTLTGVAMVLKEYPKTAVNVVGYTDSTGSHDL
                     NMRLSQQRADSVASSLITQGVDASRIRTSGMGPANPIASNSTAEGKAQNRRVEITLSP
                     LQ"
     gene            7359..9692
                     /locus_tag="OPV72_003376"
     CDS             7359..9692
                     /locus_tag="OPV72_003376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin guanine dinucleotide-containing
                     S/N-oxide reductase"
                     /protein_id="HCR9915586.1"
                     /translation="MTHAPSRHSVLTAAHWGPVRVETDGERIFASYGELPTAHQNSLQ
                     TVVHDQVHSKTRVRFPMVRKGFLASPDKPQGIRGQDEFVRVSWDDALDLIHAQHKRIR
                     ESYGPSSIFAGSYGWRSNGVLHKAATLLQRYMALAGGYTGHLGDYSTGAAQAIMPYVV
                     GGNEVYQQQTSWPVVLEHSEVVVLWSANPLNTLKIAWNASDEQGLDYFAALRQSGKRL
                     ICIDPMRSESVDFFGDKMEWIAPHMGTDVALMLGIAHTLVENGWQDEAFLARCTTGYD
                     RFADYLLGTTDGTAKTAEWAAEICGVSAVKIRELAEIFHHNTTMLMAGWGMQRQQFGE
                     QKHWMIVTLAAMLGQIGTPGGGFGFSYHFANGGNPTRRAAVLASIQGSIPGGVDAVDK
                     IPVARIVEALENPGGFYQHNGMDRRFPDIRFIWWAGGANFTHHQDTNRLIRAWQKPEL
                     VVISECFWTAAAKHADIVLPATTSYERNDLTMTGDYSNQHLAPMKQVVSPRWEARNDF
                     DVFAELSERWEAGGYARFTEGKSELAWLETFYNIAAQRGASQGVTLPPFAAFWQANRL
                     LEMPENPANAQFVRFADFRRDPDNHPLKTASGKIEIYSARIASYGYADCPGHPMWLAP
                     DEWHGNADAGQVQLLSAHPAHRLHSQLNYSSLRERYAVAGREPVTIHPQDATTRGIVD
                     GDTVRVWNHRGQVLAGAVVTDGIRPGVICIHEGAWPDPEPTAGGICKNGAVNVLTKDL
                     PSSRLGNGCAGNTALVWFEKYTGPALPLTAFDPPANS"
     gene            complement(9661..10101)
                     /locus_tag="OPV72_003377"
     CDS             complement(9661..10101)
                     /locus_tag="OPV72_003377"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HCR9915587.1"
                     /translation="MIRKSQSEDMASILALWMKSTIYAHPFIEERYWHESEAIVRDVY
                     LPAAQTWVWEENGQLKGFVSVLEARFVGALFVAPDALRHGIGKALLEYVQQRFPLLSL
                     EVYQKNQSAVNFYHALGFRIEDSAWQEDTSHPTWIMSWQADQTP"
     gene            complement(10079..10660)
                     /gene="tag"
                     /locus_tag="OPV72_003378"
     CDS             complement(10079..10660)
                     /gene="tag"
                     /locus_tag="OPV72_003378"
                     /EC_number="3.2.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HCR9915588.1"
                     /translation="MQRCDWVSQDPLYIAYHDNEWGVPETDSRKLFEMICLEGQQAGL
                     SWITVLKKRENYRACFHQFDPIRIAAMQEEDVERLLQNTGIIRHRGKIQAIISNARAW
                     LAMEQNGESFADFVWSFVDGQPQITQAASLDKIPTSTPASDALAKALKKRGFKFVGTT
                     ICYSFMQACGLVNDHITGCFCHPGEKHDSQIPE"
     gene            10817..11521
                     /locus_tag="OPV72_003379"
     CDS             10817..11521
                     /locus_tag="OPV72_003379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HCR9915589.1"
                     /translation="MIVRKRRGRRTLRCLAGLMACSFFINTTYAWQQEYIAEAAPGHT
                     TERYTWDSDHQPNYNDILAERIQSTQNTVGPVLSLADETPLDATSGISMGWNFSLSRR
                     VTTGPVAALHYDGSTSSMYNEYGDSATTLALTDPLWHASVSTLGWRVNSQFGDVRPWA
                     QISYNQQFGENIWKAQSGLSRMTAGNQAGNWLDVTVGADVLLNPHLAAYAAFSQAENS
                     ATDSDYLYTLGVSARF"
BASE COUNT         2798 a         2862 c         3071 g         2825 t
ORIGIN      
        1 tcatagacgc ggttatctct attgattggc aagaattatt tcaggaatac attaacgctg
       61 gcggtacgga tattggcgtt agaatagctg cgggtgcttg agactgtttg tctcaggtat
      121 tcaccaaaag gcagacagag aaaatcccca cctgactata cccaaaataa ttcgagttgc
      181 ttaaaggcgg caagggagtg agtccccagg agcatagata actatgtgac tggggtgagc
      241 gagcgtagcc aacacataag caacttgaag tatgaagggt atataaatca aaagtgcact
      301 gcgcccatta ttgatctctt caataacgaa gcgatctcct gcagtatttc agaacgtcca
      361 actatgccga tgatcgatga catgctcatg aaggcatttg ccagacttga tgcgggtacc
      421 aatccggttc ttcattcaga tcagggctgg caataccgtc attgatggta ccagtatcag
      481 ttacgagagt ttggcatcat ccaaagtatg tcccgcaaag gcaactgcct tgataatgcc
      541 tgtgcagaat tttttttcgg cactttaaaa tcagaaagtt tttacaccag taaatttaag
      601 gatattgatg aacttaagat agctattgag gattacatac gatactacaa tacccgacga
      661 attagcctta gatttaacgg actcagcccg gttgaatacc gcctaaagag ctatccaggc
      721 agaaattaac aaggtctgta cagggatgct atcaggaaac ctgaacgttg gtggatacgc
      781 tcacgtaaat gtctgctatg agcgaggagc ggacgcccta tttcacaaaa attagtattg
      841 ttctacaagt aactctcaca atgaggtttt atgaaaatca gaaggttcag taatggggat
      901 gaaatatcgt tattcagagt ttttttctca tctgtacata cgatcgcatc acactactac
      961 acacgtgaac aaattgatgc ttgggcccca gcagatatcg acctggagcg atgggccaat
     1021 cacattaagg aattacaacc ttttgttgta gagctggatg gtgaaatagc tggatatgca
     1081 gatgttcaac caaatggata cattgatcat ttctttgtat caggaaccta ttcaagacag
     1141 ggggtaggga cactactgat gaattgcatt catgaggaag ccagacagcg tggaattagt
     1201 gaacttactt caaatgtaag taaggctgcg gaagtgttct ttctacgaca cggctttcat
     1261 atagtggagc gaggctttcc tatttgccgt ggagtgacat tacaaaatgc tctgatgaga
     1321 aaatgtttgg cgaaataata gtcagcctgc agaaaggcag cattgttctt ttgccttgtt
     1381 gaactcagta aaccgctaca atgagcaacg tccgctgctg gcgcaaagcg gacatcagta
     1441 ttcaaaaaat gaaaaacgac gacttgatgt atatcgtttg ctatacatgg tggttgtgct
     1501 attcttgtaa agcaaatgct atacaagggg tgtctcatga aatcagatgt tcaacttaac
     1561 cttagagcta aggagtcgca gcgggcgctc attgatgcag ctgcggaaat ccttcacaag
     1621 tcacgtacag atttcattct ggaaacggcc tgccgggctg ccgagaatgt gatccttgac
     1681 cgccgtgtat ttaactttaa cgatgagcaa tatgaggagt tcatcaatct gcttgatgca
     1741 ccggtcgcag atgatcccgt tatcgaaaaa ctgctggcaa ggaaacctca gtgggacgtg
     1801 taacagcacc agaacctttg tccgcttttc atcaggtagc tgagttcgtc agcggtgaag
     1861 ctgtgctcga tgactggttg aagcaaaagg gcctcaaaaa ccaggctctc ggagcggcca
     1921 gaacatttgt ggtgtgcaag aaagacacga agcaagtagc cggtttttac tctctggcca
     1981 ccggtagcgt caaccataca gaagcgacag gcaaccttcg gcgtaacatg ccagatccca
     2041 tccctgtcat tatacttgcc cgtcttgctg tcgatctctc attccatgga aaagggcttg
     2101 gggctgattt acttcatgat gcagtgcttc gttgctatcg ggttgccgag aatattggtg
     2161 tacgtgcaat catggttcat gcacttaccg aagacgccaa aaatttctac attcaccatg
     2221 gtttcaaatc atcacaaact cagcagcgaa cattgttcct taggctccct caatagaatg
     2281 caaagactgt tatgttcaaa tcgctataag cgataatttg atagaacgtc taaggttaaa
     2341 ttcaggaaga atacgacgaa caaaatattg atgagacagg aatccgcgtg atgcaagaaa
     2401 gcaacggaat ggataatccg attgcggaca atgttattta gttatagcca gaaacaaaaa
     2461 agagcccatg tattaaatgg actctttcgc tgatgcctcg gttaatctgt ccaggttttg
     2521 gggtcagtac aaagtgagcc cacctctgcc attcttgtgg cgttatgcat tctcaaggca
     2581 ctctgttaat tttatcttgt tggcgtttta taggcccgat aacccattat gttatcgggc
     2641 atttttttaa cgtaatggta attccgtcag acaggtctgg ctgtcatctc tggtggcaat
     2701 ggcatgtgac gccgttttac cgttgtagct tacttcgagc gtcccttcca tattgcgcgg
     2761 tagccaaaca ccgataaatc cgtttcgata gctttgcatc tctttttgta cgatgacagc
     2821 gcctttactg tctgtcactt ttacagtgaa cggtttattc ggcatttctc cctgacagcc
     2881 ggaaaggctg tggttaaaac aggggtgtgt ccgccattca tagggcgcaa aagagagata
     2941 gaatttgtcg cctaacggta gcgtataaat ctgctctccg tcagataatt tgagctcggt
     3001 actggtaatc gacgcggagt aaggcaaagg acggctctgc ggcgtctgat caatcgtatc
     3061 cacgatctgc tcaaccgttt ttcccgccag cccatgttgc gccagaaaag cggattctga
     3121 ggatgccgca agcgcggagc cgctggcgca taaacccaaa agtaataacc atgatgattt
     3181 cgacataact tcaattcctt gtgaacaatc tccttgccta ctataggggt tcccctaagg
     3241 gaaaggtcaa agggacgcag ggtaaagtaa tgcaaagtta tgctgggggg ggagatgggg
     3301 aattggaata aaaaaaatcc ccgccatcag gcagggattc aaaattctga gctttttaag
     3361 cttacaggct ggttacgttg ccagctgccg ggcctttagc gccgctttcg atggtgaagg
     3421 aaactttctg accttcgtcc agagatttgt aaccatcgtt ctgaatagcg gagaagtgta
     3481 cgaacacgtc tttagaaccg tcatcaggag taataaagcc gaagccttta tcagcgttga
     3541 accattttac gataccagtc attttaccgg acatagtgta ttacctttta aaaaataagt
     3601 gtgcctttcg gcgttatggc gtgctttaca gattttttaa gcgttaagga aatgcgcact
     3661 acgaggggta tctaatggat aactcttgaa gggacttgcc ttactaaact gctttaatgg
     3721 tctgtacgtc aaaccgttga gcacattaac tcatgtaatg ccgggcgatg caacttttat
     3781 tttactttat ttctccaggc cagtaatcgg gcgggggaaa cggcccttac gcaggaccgt
     3841 taaaacagaa aggggtaaaa attgctccat caattgctta cttaagcgtg ggttcgcctg
     3901 tatcaggcgc atcaatttga gctctgctgg cgtgggtttt tcgcgtttcg attcccattc
     3961 ctgaaccatg gcaaccgtta cgcccagcgc tctggcgaat tcatctgttt ttagtcccgt
     4021 tcctctccgt aactgttcaa attcggtaaa aggattgggt ttttgcgtca gggtgatctt
     4081 tcgtgtttca tctttaaaaa caatttgttc caggctgctc agcagctcaa acatcggatc
     4141 tttatattcc attgagaact cctgtaaatc acacagcggg atcgtgaaat gcatcgaagc
     4201 ctcttaagaa tagtcgggaa acttgcgggt ggggggcgac gcgccgccag gaagcgctat
     4261 cgattcgttt cgatgcctta cgctacgcga cttttaggac gctaacaatt tgatccagga
     4321 agatatatcc gtctttcaga aaataattgt aaagattaaa aaaatattac atcccccgct
     4381 ggaaagcttt cttgccgcgt tttttatcgc agtgtcaggt taaaaattaa caataaaata
     4441 ataaattaag cattgatgca gataaacata attttccgct acaagatcgc gtggaaaggg
     4501 tatcctgcaa gcctgacctg gactatcctt gtaagccgtc aggcacgcag gtgtcgttgt
     4561 gcgcattttt gggtgaaagg agtattaaca atggcgacag gtaagtcctg ctctcgctgg
     4621 tttgcgcctg ttgtggcgtt attaatggtg tttagcctga gcgggtgttt tgataaagaa
     4681 ggcgatcagc gcaaagcgtt tgtcgatttc ctgcagaata cagcaatgcg tagcggagag
     4741 cgtttaccaa cgctgacggc cgatcagaaa aagcagtttg gtccgttcgt gtctgattac
     4801 gcgatactgt atggctactc gcagcaggta aaccaggcga tggattccgg tctgcgcccg
     4861 gtggtcgata gcgttaacgc catccgcgtt ccgcaggatt atatgacgca acgcgagccg
     4921 ctgcggcagg caaatggttc gttaggcgtg ctggcgcaac agttgcagaa tgcaaaactg
     4981 caggctgatg ccgcgcatgg cgcgttaaag caggccgatg acctgaaacc tgtgtttgat
     5041 caggtctaca aaaaagtggt caccgtgccg gcagatgctt tgcagccgct gatcccggcg
     5101 gcgcagatct ttacgcagca gttggtacaa gtgggcgatt atattgcgca acagggcgag
     5161 caggtgagct ttgtcgcgaa cggcattcag ttcccgacct cacagcaggc cagccaatat
     5221 aatgcgctga ttgggccgtt ggcctcgcag catcaggcgt ttaatcaggc ctggacggcg
     5281 gcggtaaacg cgacccagta atgacagtct gcccgataag cgcaagccag cgcttatcgg
     5341 gcctgtagcg ttatcccgcc gcttgcggat tgacgcagtt cttctctatt tttccctgca
     5401 gcgcatcaat caaattatcc accgcacagg ccatcatgtt gtagcgcgtc tcatgcgttg
     5461 ccgagccaat atgcggcacc gcgacgacat tagacatgtt cagcaggggc gaatccacag
     5521 atagcggttc ctgttcaaag acatccagac ctgccgcata tatttcaccg ttttgcagcg
     5581 cggcaatcag cgcgttttca tcgaccaccg ggccgcgtcc ggcattaata aaaatggcgg
     5641 acgatttcat tctggcaaac tgtgttgcgc caaacagatg tcgcgtttct gccgttagtg
     5701 gcaggatcac gcagacaaaa tcggcctcct gcaacaacgt atccagatcg cagtagcggg
     5761 cgttaaaccg gtcttccgcc tcctgatgcc gccgacgggc gtgatagaga accggcatgg
     5821 taaacccaaa gtgcgctcgc tgcgccagcg ccatcccgat acgccccatc ccaacgatac
     5881 cgagtgtttt gtgatgcaca tcgacgccaa accatgccgg gccaatgctt tctgtccatt
     5941 cacccgcctt aacccgttct gcgacgtcca ccacgcggcg ggcagtggcc agcatcaacg
     6001 ccatcaccgt atcggcaacg gtttccgtca aaacggcagg cgtgtgcatc aggactattt
     6061 tgcgggcagt aagggcgtcc acctcgacat tatcgtatcc caccgagatg gtcgacgccg
     6121 cgcgtagcgc cggcattttt tccagcagcg cgcggttaac ggtttcgctg gtgcccagaa
     6181 ggccttgcgc gctggcaaat gcctgcgcgt gtcgcgcgac cgtttccgga tgcaggttcg
     6241 gtacctgggt gacggtaaaa tgcgcctcca ggcgatgcag caaatcatca ggcagggttt
     6301 tgtagagaat gatggacggc ttcatgcgac tctccgtaaa tcaaaaggta agcgcggcat
     6361 gcgccaaccg gaacaggctt attattaacc cgtttagcca tcatcgacca gccgatttcc
     6421 ccgctgtcgg cagccgtgtc gtggtaaata gtgaatgaat actgaataat gcgacgtgta
     6481 tccggtctgg cgagggaata atgcaggccg ggtaaagcat gccgccttac ccggtacggt
     6541 agtttactgc aatggactca aggtaatttc gacgcggcgg ttttgcgcct taccttctgc
     6601 cgtactgttg ctggcgatcg ggttcgccgg acccattccg ctggtacgga tacggctggc
     6661 gtcgacgccc tgggtgatca gcgaactggc gacggagtca gcacgctgct gcgacagacg
     6721 catattcaga tcgtggctac cggtactgtc ggtgtagccc accacattga cggcggtctt
     6781 gggatactct ttcagcacca tcgccacgcc ggtcagcgtg ttagcgcctg ccggtttcag
     6841 cgtcgcgctg ctgctgtcga aggtgacatt attcggcata ttcagaatga tattatcgcc
     6901 gcttcgcgtc acgctaacgc ctgtgccccg cattttgtca cgcagtttcg cttcctgtac
     6961 gtccatgtag taacccacgc cgccgcccag cgccgcgcca gccgccgcgc caatcagcgc
     7021 gcctttaccg cgatcttttt tggaggagga gagcgcgccg atgcctgcgc cgaccagcga
     7081 tccaataccc gcgccaatgc cggatttacc tgcttcgcgt tcgccggtgt aagggtttgt
     7141 tgtgcagcca gatactgcca gggcgccgct cacgatggca gcaatcacaa atacacgttt
     7201 tttcatctta aatccttatc acttttttat ttttaccaca gcgaccgtgg cggttgatta
     7261 tgacgtctgc acatgaagaa aattccaggg aaaactctga aatttgtaag taacattgat
     7321 cggcaaaata aataatccca ataattcagg agcgaacctt gacccacgca ccatcgcgtc
     7381 attcggtatt gaccgccgca cactgggggc cagtccgtgt tgaaaccgac ggagaacgca
     7441 tttttgcttc atatggcgaa ctcccgacgg cacaccagaa ctccctgcaa accgttgtgc
     7501 atgaccaggt acacagcaaa acgcgggttc gcttcccgat ggtgcgtaaa gggttcctgg
     7561 cttctcccga taagccgcaa ggcatacgcg ggcaggatga gtttgttcgc gtaagttggg
     7621 atgacgcgct ggatctgatc cacgctcagc acaaacgtat tcgtgaaagt tatggaccat
     7681 cgtccatctt cgccggctcc tacggttggc gttcgaacgg cgtattgcat aaagcggcta
     7741 cgctattgca gcgttacatg gcgctggcgg gagggtatac cggccatctt ggcgattatt
     7801 ccaccggcgc ggcgcaggct atcatgcctt atgtggtggg tggtaacgag gtttaccagc
     7861 agcagactag ctggccggtg gtgctggaac atagcgaggt ggtggtgctc tggagcgcga
     7921 acccgctgaa tactctgaaa attgcctgga acgcctcgga tgaacagggg ctcgactatt
     7981 ttgcggcgct gcgacaaagc ggcaaacgcc tgatctgcat cgatccgatg cgatcggaaa
     8041 gcgtcgactt ttttggcgat aagatggagt ggatcgcccc acatatgggc accgatgtgg
     8101 cgttaatgct ggggatcgct catacgctgg tggaaaacgg ttggcaggat gaagcgttcc
     8161 ttgcccgctg cacgacgggc tatgaccgct tcgctgacta tcttttgggc acgaccgacg
     8221 gtacggccaa aacagcggaa tgggcggcgg aaatttgcgg cgtttctgcg gtgaaaatcc
     8281 gcgaactggc ggaaatattt catcataaca ccaccatgtt gatggctggt tggggaatgc
     8341 agcgtcagca gttcggcgag caaaagcact ggatgatcgt tacgctggcc gcaatgctgg
     8401 ggcaaattgg tacgcctggc ggcgggtttg gtttttctta tcattttgct aacggcggaa
     8461 acccgacgcg ccgcgccgcc gtgttagcgt cgatacaggg gagcatccct ggcggggtcg
     8521 atgcggtaga taaaataccg gtggcgcgta ttgtcgaggc gctggaaaac cccggtgggt
     8581 tttaccaaca caatgggatg gatcgccgct tcccggatat tcgttttatc tggtgggcgg
     8641 gtggcgcgaa ctttacccat catcaggata ccaaccgtct gattcgtgcg tggcaaaaac
     8701 cggaactggt cgttatctcg gaatgtttct ggacggccgc cgcgaaacac gcggatatcg
     8761 ttctgcccgc gaccaccagc tatgagcgta acgatttaac catgaccggc gactatagca
     8821 atcagcattt ggcgccgatg aagcaggtcg tgtcgccccg gtgggaggcg cggaatgatt
     8881 ttgacgtttt tgctgaactg agcgaacggt gggaagccgg cggttatgct cggttcaccg
     8941 aaggaaaaag cgagctggcg tggctggaga ccttctacaa tattgccgcc cagcgtggcg
     9001 ccagccaggg ggtgacgctg ccgccgtttg ccgcattctg gcaggctaac cgtttactgg
     9061 agatgccgga aaatcccgcc aacgcgcagt ttgtgcgctt cgcggatttt cgccgcgatc
     9121 ctgataacca tccgctaaaa acggccagcg gcaaaatcga aatctattct gcgcgcattg
     9181 ccagctatgg ttatgcggat tgtcccggtc atccgatgtg gctggcgccg gatgagtggc
     9241 acgggaacgc cgatgcgggg caggttcagc tactttccgc gcatccggcg caccgtctgc
     9301 atagccagct caactacagt tcgttacggg agcggtatgc ggtagccgga cgcgaaccgg
     9361 taacgattca tccgcaggat gcgacaacac gcggaatcgt cgatggcgat acggtacgcg
     9421 tctggaatca tcgcgggcag gttctggcgg gcgcggtcgt taccgacgga attcggcctg
     9481 gcgttatctg tattcacgaa ggcgcatggc cggaccctga acctaccgca ggcggcatat
     9541 gcaaaaacgg cgcggtaaac gtcctgacaa aagatcttcc cagttcccgg ctggggaacg
     9601 gttgtgcggg caacaccgcg ctggtctggt ttgagaaata taccggcccg gcgctaccgc
     9661 ttacggcgtt tgatccgcct gccaactcat aatccaggtg gggtgggagg tatcctcctg
     9721 ccaggcgcta tcttcaatac gaaaaccgag cgcatggtag aagtttacgg cggattgatt
     9781 tttctggtaa acctcaaggc tcagcagagg aaaacgttgc tggacatatt ccagaagcgc
     9841 tttgccaatg ccgtgtctta acgcgtcggg ggcgacaaac agcgccccga caaaacgggc
     9901 ttccagtacg ctgacgaagc ctttcagttg cccattttcc tcccataccc aggtttgcgc
     9961 ggcgggtaaa tagacgtcgc gtacaattgc ttcgctctcg tgccagtaac gttcttcgat
    10021 aaagggatgg gcataaatgg tacttttcat ccacagcgcc agaatagacg ccatgtcttc
    10081 actctgggat ttgcgaatca tgtttttctc ccggatggca aaaacagccg gtaatatggt
    10141 cgttgaccag tccgcacgcc tgcataaagg agtaacagat agtcgtaccg acaaacttga
    10201 aaccgcgttt tttcaatgcc ttagcaagcg catcggacgc aggtgttgag gtggggatct
    10261 tatccaggct ggccgcctgg gtgatctgcg gctgaccatc aacgaatgac cagacaaaat
    10321 cggcgaaaga ctcgccgttt tgctccatcg caagccaggc gcgggcgtta ctgataatgg
    10381 cctgaatttt accgcgatgt cgtatgatgc ccgtgttctg tagcaggcgt tcaacatcct
    10441 cctcctgcat agctgcgatg cgtatcgggt caaactgatg aaaacaggcg cggtagttct
    10501 ccctcttttt aagcacggtg atccaggata aaccggcctg ttgaccttca agacagatca
    10561 tttcaaacag ctttctgctg tcagtttccg gtacgcccca ctcgttatca tgataggcaa
    10621 tataaagggg gtcctggctg acccagtcgc aacgctgcat agacttcctc gttattgtgg
    10681 ttaccgcgaa aatttccttc aacccgcctt gacgggtccg ctaaaaggac aatagttaat
    10741 acagggctga tgtccgacat ccttcattca atgacaataa tatcgccgaa ttcggctcta
    10801 ctctggagtc gcgttgatga ttgtaagaaa acgccgtggt cgccggacat tgcgttgtct
    10861 ggcgggcctt atggcctgct cgttttttat caataccacg tatgcctggc aacaagaata
    10921 tatcgctgaa gcggctccgg ggcatacgac ggaacgctat acctgggaca gcgatcacca
    10981 accgaattac aacgacatac tggccgaacg tattcagtct acgcaaaata cggtgggtcc
    11041 ggtgcttagc ctggcggatg aaaccccgct tgatgcgacc agcggtatca gtatgggctg
    11101 gaatttttcg ctttcccgac gcgtaaccac tgggccggtc gcggcgctgc attacgacgg
    11161 ttcgacgtca tcaatgtata acgaatatgg cgatagcgcg acgacattag cgcttaccga
    11221 tccgttatgg catgccagcg tcagtacgtt aggctggcgg gtaaactcgc agttcggcga
    11281 tgtccgtccc tgggcgcaga tcagctataa ccaacagttt ggggaaaata tctggaaagc
    11341 gcagtccggg ttgagtcgta tgaccgcagg aaatcaggcg ggaaactggc tggatgtcac
    11401 cgtaggcgcg gacgtgttac ttaacccgca cctggcggcg tatgcggcgt tttctcaggc
    11461 ggaaaacagc gctacggata gcgattattt gtataccctg ggggtgagcg ccaggtttta
    11521 acgggataaa ccgtcgcctg gacttattag aagttc
//
LOCUS       DAJVBX010000154        11388 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.154, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000154 DAJVBX010000000
VERSION     DAJVBX010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 11388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11388
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.154"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(39..674)
                     /locus_tag="OPV72_003380"
     CDS             complement(39..674)
                     /locus_tag="OPV72_003380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915590.1"
                     /translation="MKLSVTLAFFGYMMVSSMAQASDINMWREPKPVVKEGKYYSLIM
                     DRGELQKAVKSSSNNYLFSEKGAGVKPLVLIGSPVEISEFMLQNKTRSIENHIKGLPD
                     IYMGVTKYKPKQRFTGLFPLQDILTQTVDQVSKFVPGTDITDAVGIPSDLKALQQAIL
                     AMKQKDKISKNILYVKFSYLPEDGMVKVGSKTVSFGRILEKMQQSNRTLRR"
     gene            1443..1772
                     /gene="hdeB"
                     /locus_tag="OPV72_003381"
     CDS             1443..1772
                     /gene="hdeB"
                     /locus_tag="OPV72_003381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-activated periplasmic chaperone HdeB"
                     /protein_id="HCR9915591.1"
                     /translation="MNKFSLATAGIIVAALVTSVSVNAATDTTKTNVTPKGMSCQEFV
                     DLNPQTMAPVAFWVLNEDEDFKGGDYVDFQETETTAVPLAVELCKKNPQSELSKIKDE
                     IKKELSK"
     gene            1915..2700
                     /locus_tag="OPV72_003382"
     CDS             1915..2700
                     /locus_tag="OPV72_003382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OBAP family protein"
                     /protein_id="HCR9915592.1"
                     /translation="MKILPLALFIIPFLAGCGANNTPPQTPIPGEKTSAKLRTLETGA
                     AAIQSRPPVDAISTYLDGFHFYSGDKNGQMEAHHYVTVLNEDVMQAVIYDGNTKNARL
                     MGVEYIISERLFKTLPPEEKKLWHSHQYEVKSGSLVAPGLPQVADKALMSKIVNTYGK
                     TWHTWHTDRDKTLPMGIPALMMGFTGDGQLDPALLADRDRRLGIDTQAIKRERQDLPE
                     HPVIKGANAWEQGEVIQLQRVQGSGEHGRGDTAHFGISEQSRQ"
     gene            2829..4613
                     /gene="treZ"
                     /locus_tag="OPV72_003383"
     CDS             2829..4613
                     /gene="treZ"
                     /locus_tag="OPV72_003383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malto-oligosyltrehalose trehalohydrolase"
                     /protein_id="HCR9915593.1"
                     /translation="MSSKIFCKSWGAEYIAADVVRFRLWATGQQKVMLRLAGKDQEMQ
                     ASGDGWFTLDVSGVTPGTEYNFVLSDGMVLPDPASRAQKTDVNGPSYVIDPGSYAWRN
                     TGWKGSRWEQAVVYEMHTGTFTPEGTFHTAIAKLPYLAELGVTVIEVMPVAQFGGERG
                     WGYDGVLLYAPHSAYGTPDDFKAFIDTAHGYGLSVILDIVLNHFGPEGNYLPLLAPAF
                     FHKERMTPWGNGIAYDVDAVRRYIIEAPLYWLTEYHLDGLRFDAIDQIEDSSARHVLV
                     EIAQRIREDITDRPIHLTTEDSRNIISLHPRDQDGNAPLFTAEWNDDFHNAVHVFATG
                     ETQAYYNDFADAPEKHLARALAEGFAYQGEISPQTGEPRGVKSTGQPPVAFVDFIQNH
                     DQVGNRAQGDRLITLAGAERTKVLLATLLLSPHIPLLFMGEEYGESRPFLFFTDFHGD
                     LARAVREGRAKEFADHAGENVPDPNAPETFQRSKLNWKQQHSEEGKAWLAFTRELLLL
                     RQKHIVPLLSAARESSGTVLQTAPGFIAVSWRFPGGTLSLALNISATTVLLPDLPGKT
                     LFAWPNESTGSLSQHSLIVRLAQGESAS"
     gene            4610..7138
                     /gene="treY"
                     /locus_tag="OPV72_003384"
     CDS             4610..7138
                     /gene="treY"
                     /locus_tag="OPV72_003384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malto-oligosyltrehalose synthase"
                     /protein_id="HCR9915594.1"
                     /translation="MIPTATYRLQFRNSMTFDRAAALVPYLKNLGISHLYASPIFTAT
                     KASTHGYDVTDANEIEPSIGGREGFERLVAELKAQGLGLIIDIVPNHMASSLENAWWR
                     DVLEYGKESRYARHFDIDWSRRLTLPFLGDTFDAVLGNGEIAIKPDPVTGKPTFAYYD
                     NYYPLAPATWQGREAEILALTDKAAIADLHERQPWKLMSWRDAARSLSYRRFFEVTGL
                     VGMRVEDKIVFDDTHRLILELVRTGAVDGLRIDHIDGLADPKAYLARLRQEVGPACYI
                     TVEKILAKGEQLPDDWPVSGTTGYEFIASLAEVLVDDKQIDNLRQAYETVTGAPVDMR
                     AELRAAKLLMVDRNFEGEFTRLLALALSIASELQIAQEESVVRQALRELLIAFPVYRT
                     YGTAEGLPPTDICLLHRIVERVKTLENPPQPEALTFLSRLLTGDVPVSSQEEATQFRV
                     RFQQLTGPLMAKSVEDTLFFRQNMGLALNEVGAEPVTHHFSIERFHHEMKTRQARQPD
                     ALSGTSTHDTKRGEDARARLYTLTEAPEQWSECLARWRQMNQTHVKFLNDGTAPKSAD
                     TWMLYQALTGVWPPMLQPQDETGLNALKIRFEAFVEKALREAKLRTDWVDSNEAYETA
                     MLDYARYLLAPDNQTFLQDFYRSLQPFIRAGLVNSLTQTVIKLTAPGVPDIYQGSEAL
                     NFSLVDPDNRREPDFATLAQQLDQLTPGVFSREESWLDGQVNQYATAALLRLRQQNHE
                     LFRFGDYIPLRAVGQRADKVIAYARVNHDDALIVVAPRLVFAECDGLLSQSHSGFWSG
                     TDIIIPGQLNQRRYRNVLTQERLMPGERLSLASHQGGVLVLMSD"
     gene            7195..9270
                     /gene="glgX"
                     /locus_tag="OPV72_003385"
                     /pseudo
     CDS             7195..9270
                     /gene="glgX"
                     /locus_tag="OPV72_003385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460517.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen debranching protein GlgX"
     gene            complement(9383..10603)
                     /locus_tag="OPV72_003386"
     CDS             complement(9383..10603)
                     /locus_tag="OPV72_003386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCR9915595.1"
                     /translation="MDLISPCSHKAQKVCNNTGSVKWDFIERHFGDGAGKLLPMWVSD
                     FDFACPPEVQAALHQRIEHGVFGYSERDEAYFNALLHWFSSRHQLTLKQEWVCSVEGV
                     VPGLALLVQMLTHPGDGVVVQGPYYGSFAKIITLNGRKLLENPLSESPDEGYQMDFCQ
                     LERLFRHERPPLMILCNPHNPTGRCWSANELEQLLLLCEAYDVTLISDEIWADLLLPC
                     ETFTSVLHLGERWHKRVISATAASKTFGLSSLRISNFLIPDPTLRQRFLSRLDAHGLD
                     VFNALSVQAATTAWNESRQWLDSLLDYLAENRRWFVEQATEHLPWARIVPAQGTYLLW
                     MDCKKLGLDDEQLKWVMADVAGIAPSMGSGFGPAGSGFIRLNLGCPRTYLEMAIDGLK
                     RISVKTIKGIPTGG"
     gene            complement(10560..11262)
                     /locus_tag="OPV72_003387"
                     /pseudo
     CDS             complement(10560..11262)
                     /locus_tag="OPV72_003387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460515.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         2830 a         2821 c         2957 g         2780 t
ORIGIN      
        1 taacattcca gaagctggaa atactgcctg cttcctgctt atctacgcag ggtacgatta
       61 ctctgctgca ttttctccag aatacgacca aaagaaactg ttttgcttcc tactttcacc
      121 attccatctt ccggcaagta gctaaatttg acgtacagta tatttttgct gattttatct
      181 ttttgcttca tagccaaaat ggcttgctgt aatgctttta ggtcggaggg gattcccacc
      241 gcatcggtga tatcggtacc gggcacaaat ttcgatacct gatcaacagt ttgagtcaat
      301 atatcctgta gcggaaataa gccggtaaaa cgttgtttgg gtttatattt tgtcactccc
      361 atataaatgt caggtagacc tttaatgtgg ttttcaatgc tgcgagtttt attttgcaac
      421 ataaattcgc taatctctac cggagagccg atcaatacca gcggcttcac tcctgcacct
      481 ttttcggaaa agagatagtt attgctgctg ctttttactg ctttttgcaa ctcgccacga
      541 tccatgatta agctgtaata tttaccctct ttcacaacag gtttgggttc acgccacata
      601 ttgatatcgc tagcttgtgc catactggat accatcatgt aaccgaaaaa cgccaatgtt
      661 acggatagtt tcattaactt taccttttta attagccaaa aaaaatagca ctcgtaaaaa
      721 gtataaagcc gtggttgcaa caaaacttaa acgtcgctca cttaaccgat aagcatttat
      781 ttatcttaat tatataaatt tccctccaaa taatacctga attattaccc tttggattca
      841 actgcttgca gttatagtgc taaataacaa taaatctact ggaagtatac agtttgtgtg
      901 caaaaggtat ttttatgatt acggaaacct gaaattgtcc gactatctgt aaatgctatg
      961 aaattgtatt gtagattcga ttgcgcccgg tgctgatgac taccggggca atagtggttg
     1021 gtttagccct gataaggttc gccagcggtg tagacaccgc aagccgtttt ggacagggct
     1081 ggtggttgcc tccgggatgc tgacaggcaa tctgtttacg atgtttgttc tgcccaccgt
     1141 ttgtgtctgg ctggcgcgcg attgcgacgg catgtcagag cgaagttctc tttcatcagc
     1201 tcaacgtagc gcatactcgt catttgctgt tgtcgtggtc tactttttcg ccctaaaatc
     1261 tgctcgccat gttgctttat tcatcaaaca tcaaaatcag tcaacgtaaa tatcaataat
     1321 agccatatca cggagggtga tctttattcc tgagagaggt ggggtattat tttctgcgtt
     1381 ctacattaac gggttaacgc gcagatgtag aggttattta tataattatt ggagcaacaa
     1441 caatgaataa attctccctt gctacagcag gtattatcgt ggcagcgctg gtaaccagtg
     1501 ttagcgtgaa tgcggcaaca gatactacta aaacaaacgt tacgcctaaa ggtatgagct
     1561 gccaggagtt tgttgacctc aatccgcaga cgatggcgcc agtcgctttc tgggtgctga
     1621 atgaagatga agattttaaa ggcggggact acgttgattt ccaggaaact gagacgacag
     1681 cagtgccgct agccgttgag ctttgtaaga aaaacccgca gagtgaatta agcaaaataa
     1741 aagacgaaat caagaaagaa ctctcaaaat aagagtaaac tgatatcaaa acccggcctg
     1801 tgtgtcgggt tttactattt gtgacaccgt cacaaatagc atcttccatt tcttctacca
     1861 atcacgtggt attgcactat tttcattaga gccctttcac tatatggaga cctaatgaaa
     1921 attttaccgc tggcactctt tatcattcct tttctggccg gatgcggcgc caataatacg
     1981 ccgccgcaaa cgcctattcc cggggaaaaa acatctgcca aattacgtac cctggaaaca
     2041 ggcgcggcgg ctattcaatc cagaccacct gtcgatgcca tcagtaccta ccttgacggg
     2101 ttccattttt atagcggtga taaaaacgga cagatggaag cgcaccatta cgttaccgtc
     2161 ctgaacgaag atgtcatgca ggcggtgatt tacgacggca atacgaaaaa cgcgcgcctg
     2221 atgggggtgg agtacattat cagcgaacgt ttatttaaaa cgcttcctcc cgaggaaaaa
     2281 aaactgtggc acagccacca gtacgaggtg aaatccggta gcctggtggc gccaggctta
     2341 ccgcaggtcg ctgataaggc gttgatgagt aagattgtta atacttatgg caagacctgg
     2401 cacacctggc ataccgaccg ggataaaacc ctgccaatgg gtatccctgc gctgatgatg
     2461 ggctttaccg gcgacgggca gcttgacccc gcgctgctgg ccgatcggga tcgccgtctg
     2521 gggattgata cccaggccat taaacgcgag cggcaggatc tgcctgaaca tcccgttatc
     2581 aagggggcta acgcctggga gcagggagaa gttatccagc tacagcgtgt tcagggctct
     2641 ggcgaacacg ggcgaggcga taccgcgcac ttcggtatat ctgagcaatc ccgacaataa
     2701 ttccacggtt ttacacgcag ataggaaaaa gaatgcctgt taagtgacag tgtcacgtaa
     2761 aaattagccc catagtctat gcttgttttt cggatgctgt agaggttatg agttaaacgg
     2821 agcgacaaat gagttcaaaa attttttgca aaagctgggg ggctgaatat atcgccgctg
     2881 atgtcgtccg ctttcgtctt tgggccaccg gtcagcaaaa ggttatgctc aggcttgcgg
     2941 gtaaagacca ggaaatgcag gcgagcggtg acggctggtt tacgctggat gtatccgggg
     3001 tgacgccagg tacggagtat aactttgtac tcagcgatgg catggtgctc cccgatccgg
     3061 cttcccgcgc ccaaaaaact gacgtcaatg gtccgtcata tgtgattgat ccaggcagct
     3121 acgcgtggcg caacaccggg tggaaaggca gccgttggga gcaggccgtg gtgtacgaga
     3181 tgcatacagg cacgttcact ccggaaggca ccttccacac cgcaatagcg aagctgcctt
     3241 atctcgctga actcggcgtt accgttattg aagtgatgcc cgttgcgcaa tttggcggcg
     3301 agcgcggctg gggctatgac ggcgtactgc tttacgcgcc gcattctgcc tatgggacgc
     3361 cggatgattt caaagcgttt attgacaccg cgcatgggta tggtctttcc gtcatcctgg
     3421 atattgtgct gaaccatttc ggcccggagg gaaattattt accgctattg gcgccggcgt
     3481 ttttccacaa agagcgcatg acgccgtggg gaaatggtat cgcctatgat gtcgacgccg
     3541 tgcggcgcta tatcatcgag gcgccgttat actggctgac agaataccat ctcgacggct
     3601 tacgctttga cgctatcgat cagattgagg acagtagcgc caggcatgtg ctggttgaaa
     3661 tcgcacaacg tattcgggaa gacattaccg acagacccat tcatctgact accgaagata
     3721 gccgcaatat tatttctctg catccccgtg atcaggatgg caatgcgccg ctgtttaccg
     3781 ccgaatggaa tgacgatttt cataatgccg tccacgtttt tgcgaccgga gagacccagg
     3841 cctactacaa cgattttgct gatgccccgg aaaaacacct cgcaagagcg ctggccgaag
     3901 gattcgctta tcagggggaa atctcaccgc aaaccggcga acctcgcggc gtaaaaagta
     3961 ccggacaacc cccggtcgcc tttgtggatt ttattcagaa ccacgatcag gtcggtaacc
     4021 gcgcccaggg cgacagactg ataaccctgg cgggtgctga acgaacaaaa gtattgctcg
     4081 ccacgttgct gctttcaccg catattcctc tgctttttat gggcgaagag tatggcgaaa
     4141 gccgtccttt tctttttttt accgatttcc atggggattt agcccgcgcc gttcgtgaag
     4201 gtcgcgcaaa agagtttgcc gatcatgcag gggaaaatgt tccggacccg aatgcgccag
     4261 agacctttca acgctcaaaa cttaactgga agcaacagca cagtgaagag ggtaaagcgt
     4321 ggctggcatt tacccgcgaa ctactgcttt tgcgccagaa gcatatcgtg ccgctgttgt
     4381 ccgctgcccg tgagagctca ggaacggtat tgcaaaccgc gcccgggttt attgccgtta
     4441 gctggcgttt tccgggagga acactgtcac tggcgctgaa tattagcgcc acgacggtat
     4501 tgctgcccga tttaccgggt aagactctct tcgcctggcc gaatgaatcc accgggtcgc
     4561 tttcccaaca ttctcttatt gtccgcttag cccagggaga gtctgcatca tgatcccaac
     4621 tgcaacgtat cgtcttcagt ttcgcaatag catgaccttc gatcgcgctg cggcgctggt
     4681 gccttacctt aaaaatctgg gtatcagcca tctttatgcc tcacccatct ttaccgccac
     4741 caaagcgtca acgcatggtt atgatgtcac cgatgcgaat gagattgagc cttctattgg
     4801 cgggcgcgaa ggatttgaaa gactggtggc tgaacttaaa gcacaaggtc tgggattgat
     4861 catcgatatt gtgcctaatc acatggccag ctcgctggaa aacgcctggt ggcgcgacgt
     4921 gcttgaatat ggcaaggaga gccgttacgc gcgccatttc gatattgact ggtcgcgccg
     4981 actgacgctg ccttttttag gcgacacgtt tgacgccgtg ctgggaaacg gagaaattgc
     5041 gatcaagccg gatcccgtta cgggtaaacc cacgttcgcc tattatgata attattatcc
     5101 gcttgcgcca gcgacgtggc aggggcgcga ggctgaaata ctggcgctta ccgataaagc
     5161 cgctattgct gatttgcatg agcgccagcc gtggaaatta atgtcttggc gcgatgccgc
     5221 tcgctcgctt tcatatcggc gtttctttga ggtcacaggg ctggtgggaa tgcgggtgga
     5281 agataaaatc gtcttcgacg atacacatcg gctgattctg gagctggtca gaacgggggc
     5341 ggttgacggt ttacgtatcg atcatatcga cggccttgcc gatccgaaag cctatcttgc
     5401 gcgtttacgt caggaagtgg gaccggcgtg ctatatcacc gtggaaaaaa ttctcgctaa
     5461 aggcgagcaa cttcctgatg actggccggt ttccggcacc acaggctatg aattcatcgc
     5521 ctcgctggcg gaagtactgg ttgacgataa gcagatagac aatctgcgcc aggcttacga
     5581 gaccgtaaca ggcgcgccag tggatatgcg ggcggaatta cgggcggcta aattgctgat
     5641 ggtcgatcgc aattttgagg gggaatttac ccggctgctc gcgcttgcgc tgtcgattgc
     5701 cagcgagcta cagatcgcac aggaagagag cgtcgttcgg caggcgttac gcgagttatt
     5761 aattgccttt cccgtatatc gcacttacgg cacggcagaa gggctaccgc cgaccgatat
     5821 ttgcctgtta caccgtattg tggaacgggt aaagacgctt gaaaaccctc cgcagccaga
     5881 agcgcttaca tttctgagcc gtcttcttac cggcgatgtt cccgtctcca gccaggagga
     5941 ggcgacacag tttcgcgttc ggttccagca actcaccggt ccgctgatgg cgaaatcggt
     6001 agaggatacg cttttctttc gtcaaaacat gggactggcg ttaaatgaag tcggcgccga
     6061 gcccgtcacg catcacttct ccatcgaacg ctttcaccat gagatgaaaa cccgacaggc
     6121 gcgacagcct gatgcgttat ccggtacgtc gacccacgat accaagcgag gcgaggatgc
     6181 gcgagcacgc ctgtatacgc ttaccgaagc gccggaacag tggagcgaat gccttgcccg
     6241 ctggcggcag atgaaccaga cccatgtcaa atttttgaat gatggcactg cgccaaaatc
     6301 ggcggatacg tggatgctat atcaggcgct gaccggcgtc tggcccccga tgctacaacc
     6361 acaggacgaa acaggtttaa acgcgctgaa aatacgcttt gaagcctttg tggagaaagc
     6421 gctacgcgaa gcgaagctac gtaccgattg ggtggacagt aatgaggctt acgaaacggc
     6481 aatgcttgat tacgcccgtt atttactggc gccggataat cagacatttt tgcaggattt
     6541 ttatcgttcc ttgcaaccct tcatccgcgc aggactggtt aacagcctga cgcagaccgt
     6601 tatcaaatta accgcgccgg gagtacctga tatctatcag gggagcgagg cgttgaattt
     6661 tagccttgtc gatcccgaca accgccgcga accagatttc gccacgctgg cgcagcagtt
     6721 agaccaactg acgccgggag ttttctcgcg cgaagagagt tggctggacg ggcaggtgaa
     6781 tcagtatgcc accgccgcct tactgcgttt gcgtcagcag aatcatgagc tcttccgttt
     6841 tggcgactat ataccgctgc gggctgttgg tcagcgtgcc gacaaggtca tcgcttacgc
     6901 cagagtcaat catgatgatg cgctgattgt tgttgcgccc cgactggtgt tcgccgaatg
     6961 tgacggctta ttatcacaat cgcatagcgg tttctggtca ggaaccgaca ttattatacc
     7021 cggacagctt aatcagcgtc gttatcgcaa tgtgcttacc caggagaggt taatgcctgg
     7081 tgaacgcctg tcgttggcct cacatcaggg cggcgtactg gttttaatga gcgactgagt
     7141 ttatgtgttg atgtgccgtg acaggacaac gtttaccgtg ggtggagaaa gagaatgaca
     7201 acaaacaggg cttttgaaat cagatcagga tacagccata cgcttggcgc gaattatgac
     7261 ggcgaaggcg tgaatttcgc tattttttcc gcccatgcgg aacgcgtcga gctttgtctt
     7321 tacgatccga gtggggagca tgaaatcgct cgtctggagt taccggaata taccgacgaa
     7381 atatggcacg gctatgtcac gaagttgcag cccggcgcgc tgtatgggta ccgcgtttac
     7441 ggtccttatg acccggaaaa tggtcatcgt tttaacccca ataagctgct tattgaccct
     7501 tatgcccgtg agctggtggg cgatattcag tggaacgatg cgcatttcgc gtatcaatta
     7561 cttcatgacg ataaagattt gacctttgat gaccaggata gcgcgccatt tacgcctaaa
     7621 tgtcgggtga ttgatccggc tgaggctaac tgggaggata gacaacggcc ttccataccg
     7681 tggtcgaacg ccattattta tgaaacgcat gtaaaaggct ttacccagct taattcggcg
     7741 atccctgagc ctctacgcgg tacgtttgag ggcatggggc ataaagccag cgtggattac
     7801 attaaaagtc tggggattac ctccgtcgag cttttacccg ttcactggtt cccggacgat
     7861 cagcatctgc tcgataaagg actgaaaaat ttctggggat ataactcgct gggctttttt
     7921 gcgccggcga cgcgctacta tggtccaaaa ggtattcagg gattccgcga tatggtgcgc
     7981 gctttccatg atgccggcgt cgaagtgata ctggatgtgg tctataacca tacggcagaa
     8041 gggaatgaac ttggccccac gctgtcattt aaaggtatcg ataacttctc ttactatcgc
     8101 accatgcccg atcagcatcg ctattatatt aacgatacag ggacaggtaa taccgtcaat
     8161 acctctcatc cacgggtact gcaaatggtg atggattcgc ttcgctattg ggcggagtca
     8221 atgcatgtcg acggctttcg ttttgatttg ggcaccattc ttggtcgtga gccggaaggc
     8281 tttgatcaga gaggcggctt ttttgatgcg gtaacgcaag acccggtgct ggcaaaactg
     8341 aaactgattg gcgaaccctg ggatatcgga ccgggcggct atcaggttgg cggttttcca
     8401 ccagggtggg gcgaatggaa tgataaatat cgcgatacgg ttcgcgaata ctggaaaggt
     8461 gacaacgtca caaatgattt cgccgcacgc ctgctgggtt ccggcgatct ctacgatttg
     8521 cgcggccgtc gctcctggtc aagcgttaac tttattactg cccatgacgg cttcacgctg
     8581 aacgatctgg tgtcttataa cgacaaacat aatgaagcca atggcgaaga taataatgac
     8641 gggcataatg ataaccgctc ctgtaactat ggcgcagaag ggccaaccga cgacgagggc
     8701 atcaatgcga tacgcgagcg acagaaacgt aatttcctga ccaccttact tttctcacac
     8761 ggcacgccga tgttattagc gggcgatgag tttggccgca gtcagatggg caataacaat
     8821 ggctactgtc aggacagtga aatatcgtgg gtccactggg ataatttgcc ggaaaccgcc
     8881 aatgcgctac gggagtttac ccgtcatctg attcaactgc gcgccacgca accgttgctg
     8941 cgccgggaga gctggcgtga cggtctggag atccgctggt ttaacgccgg cggaggggcg
     9001 cagtaatccg aacaatggga tgagggatcg acgataggcg tatgtattag tcgacccgat
     9061 cttcagccgg aagcggggat ctggcatgac gccttactgc ttttcaatcc gtttgaaggc
     9121 agcgtaccgt tccgtattcc gatgtgggga gaaggcggct gggtgcttga actgacgact
     9181 gccgatgacg cgcagcaggg aatgcggatt accgaagaaa tggatttcga tctggccggg
     9241 cgcagcatcg tgttattcag acgcccctga tagtgaaact gcgctccgga cccaaccggc
     9301 cttaatggcc ggttttttac tggcgctcag gcgatatcat gccgcagaaa taacaccgtt
     9361 gtcagtttac cgcccgaaaa attcatccgc ctgttggtat tcctttgatt gtcttcaccg
     9421 atattcgctt caggccgtct attgccattt caaggtaggt acgtggacat cccagattta
     9481 aacggataaa tccgctgccc gccgggccaa agccgctgcc cattgaagga gcaatacccg
     9541 cgacatccgc cattacccat tttagctgtt cgtcatccag tcccagtttt ttacaatcca
     9601 tccataataa ataggttccc tgcgccggga caattcttgc ccagggaagg tgctctgtcg
     9661 cctgttcaac aaaccagcgg cggttttccg ccagataatc cagtagcgaa tccagccact
     9721 gtctgctttc attccatgcg gtagttgccg cctgaacgga gagggcgtta aagacatcca
     9781 gcccatgagc gtccagacga gacaggaaac gctggcgaag cgtaggatcg ggaatgagaa
     9841 aattagaaat tcgcaacgac gataagccaa acgttttgct ggccgcagtg gcggagatga
     9901 cccgtttatg ccagcgctcc cctaaatgca gtaccgaggt aaaggtttcg cagggcagca
     9961 atagatcggc ccatatttca tccgagatga gagtgacatc ataagcttca cataataaaa
    10021 gcagttgctc cagctcgttg gccgaccagc aacgcccggt tggattatgt ggattacaca
    10081 aaatcattag cggagggcgc tcatggcgaa acagcctttc cagttggcaa aaatccatct
    10141 ggtagccttc atccggcgac tcgctaaggg gattctccag cagttttcta ccattaagcg
    10201 tgattatttt ggcgaaggag ccatagtatg gcccctgaac cactacgccg tcgcctggat
    10261 gcgtcaacat ttgcactaag agcgccaacc ctggtacgac gccttccacg ctgcataccc
    10321 attcctgttt taacgtgagc tggtggcgtg acgaaaacca gtgaagcagg gcgttaaaat
    10381 aggcctcatc acgttcgcta tagccaaata cgccgtgctc gattcgctga tgcaatgccg
    10441 cctgaacctc tggcgggcag gcaaaatcga aatcagaaac ccacatcggc agcagttttc
    10501 cagcgccgtc gccaaagtga cgctcaataa aatcccactt taccgaacca gtattgttgc
    10561 acaccttctg cgccttgtgg gaacatggcg atatcaaatc catcaatgaa agcgtccagt
    10621 ccctgtttga tgctcagtcc ctgcatgatg acgccgagga acaaggcaag tacgcaggcg
    10681 cttaacatta atgggatgac aggctttttg cgaattgcgc cccacagtac gatcaccggc
    10741 ggcaaaataa gaacaatatt aaaatggtat agcgactcca gcgagtggat gatgtccgta
    10801 acgcgctgcg gcgtagccac ctcgcccagc atattactgt gtccggcgat aagataaacc
    10861 acggcggcaa gcaggaaact tggcagggtc gtccaaagta aatgctgaat atgctcaaac
    10921 agagtagtgt ctgcgacaat cgcggcaaag ttagtcgagt cggacaacgg tgagattttg
    10981 tcgccgaaat aagcgccaga aacaacggcg ccagctgctg ctgcaagcga cacgtccagc
    11041 ccggcggcaa cccccattaa cgcaacgcca accgtcccgg cggaccccca cgatgtaccg
    11101 gtacagacgg agaccacgct ggttaaaaag aaggctgcaa tcaaaataga tacgtagccc
    11161 catgatgccg taaccgataa tcaacaataa caacatggag atgactggga ttagcgctaa
    11221 acccaatgac agcgttttct tcttgttttg tgatgcactc ataatggagc tccggtcagt
    11281 aaggtagtag tattacaaaa agcatacaga atgaatatgt tttattgatg gaaaacgctt
    11341 tttctgaaaa atataaatat gcatttagaa atttagaact gaaagaat
//
LOCUS       DAJVBX010000155        11380 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.155, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000155 DAJVBX010000000
VERSION     DAJVBX010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 11380)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11380)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11380
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.155"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(241..684)
                     /gene="csdE"
                     /locus_tag="OPV72_003388"
     CDS             complement(241..684)
                     /gene="csdE"
                     /locus_tag="OPV72_003388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase sulfur acceptor subunit
                     CsdE"
                     /protein_id="HCR9915596.1"
                     /translation="MTNPLYTGHPFGTTVTEETLRAIFLPLTQWEDKYRQLILLGKQL
                     PALPDECKAQAKEIAGCENRVWLGFTRSDNGTMHFFGDSEGRIVRGLLAVLLTAVEGK
                     NAAELQARSPLALFDELGLRAQLSASRSQGLNALSEAIVAATHKG"
     gene            complement(684..1889)
                     /gene="csdA"
                     /locus_tag="OPV72_003389"
     CDS             complement(684..1889)
                     /gene="csdA"
                     /locus_tag="OPV72_003389"
                     /EC_number="3.13.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase CsdA"
                     /protein_id="HCR9915597.1"
                     /translation="MNAFNPTQFRAQFPALADAGVYLDSAATALKPQAVIDATHQFYC
                     LSAGNVHRSQFAQAQRLTAQYEAARAKAARLLNAPDEKSIVWTRGTTEAINMVAQCYA
                     RPRLRPGDEIIVSVAEHHANLVPWLMVAQQTGAQVIKLPLNDRRLPDVERLPELITSR
                     SRILALGQMSNVTGGCPDLTGAISAAHAAGMVVMIDGAQGAVHFPADVQQLDIDFYAF
                     SAHKLYGPTGIGVLYGKPELLEAMSPWLGGGKMIRDVSFEGFTTQSAPWKLEAGTPNV
                     AGVIGLSAALEWLSDIDIEQAENWSRGLATLAEDALAKRPGFRSFRCQDSSLLAFDFV
                     GVHHGDMVTLLAEYGIALRAGQHCAQPLLAELGVTGTLRASFAPYNTQHDVDALVNAV
                     DRALELLVD"
     gene            2082..2309
                     /locus_tag="OPV72_003390"
     CDS             2082..2309
                     /locus_tag="OPV72_003390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgdI/YgdR family lipoprotein"
                     /protein_id="HCR9915598.1"
                     /translation="MKKTAAIISACMLTFALSACSGPNYVMHTNDGRSIVTDGKPQTD
                     NDTGMISYKDANGNKQQINRTDVKEMVALEN"
     gene            2656..3573
                     /gene="gcvA"
                     /locus_tag="OPV72_003391"
     CDS             2656..3573
                     /gene="gcvA"
                     /locus_tag="OPV72_003391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system transcriptional
                     regulator GcvA"
                     /protein_id="HCR9915599.1"
                     /translation="MSKRLPPLNALRVFDAAARHLSFTRAAEELFVTQAAVSHQIKSL
                     EDFLGLKLFRRRNRSLLLTEEGQSYFLDIKEIFSQLTEATRKLQARSAKGALTVSLPP
                     SFAIQWLVPRLSSFNSAYPGIDVRIQAVDRQEDKLADDVDVAIFYGRGNWPGLRVEKL
                     YAEYLLPVCSPLLLTGEKPLKTPEDLAKHTLLHDASRRDWQAYTRQLGLNHINVQQGP
                     IFSHSAMVLQAAIHGQGIALANNVMAQSEIEAGRLVCPFNDVLVSKNAFYLVCHDSQA
                     ELGKIAAFRQWILAKAATEQEKFRFRYEQ"
     gene            3592..3987
                     /locus_tag="OPV72_003392"
     CDS             3592..3987
                     /locus_tag="OPV72_003392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF423 domain-containing protein"
                     /protein_id="HCR9915600.1"
                     /translation="MTSRFMLIVAAISGFIYVALGAFGAHVLSKTLGVVEMGWIQTGL
                     QYQAFHTLAIFGLAVAMQRRISIWFYWSSVFLALGTVLFSGSLYCLALSHLRLWAYIT
                     PVGGVSFLVGWALLLIGAIRMKRKGASHE"
     gene            3980..5080
                     /gene="rlmM"
                     /locus_tag="OPV72_003393"
     CDS             3980..5080
                     /gene="rlmM"
                     /locus_tag="OPV72_003393"
                     /EC_number="2.1.1.186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010435097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (cytidine(2498)-2'-O)-methyltransferase
                     RlmM"
                     /protein_id="HCR9915601.1"
                     /translation="MNKVVLLCRPGFEKECAAEITDKAGKREIFGFARVKENAGYVIY
                     ECYQPEDGEKLISELPFSSLIFARQWFVVGELLQHLPPEDRITPIVGMLQGVVEKGGE
                     LRVEVADTNESKELMKFCRKFTVPLRAALRDAGVLTNYETPKRPVVHVFFIAPGCCYT
                     GYSFAHNNSPFYMGIPRLKFPSDAPSRSTLKLEEALHVFIPEDEWDERLANGMYAVDL
                     GACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFRYRPNRNNISWMVC
                     DMVEKPAKVTALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYLQAQLDEHGVNA
                     QIQARQLYHDREEVTVHVRRLWAAVGGRRDER"
     gene            complement(5139..5849)
                     /gene="fucR"
                     /locus_tag="OPV72_003394"
     CDS             complement(5139..5849)
                     /gene="fucR"
                     /locus_tag="OPV72_003394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose operon activator"
                     /protein_id="HCR9915602.1"
                     /translation="MKAARQQAIVDLLINHKSLTTEALATRLNVSKETIRRDLSELQT
                     QGKVLRNHGRAKYIHRENQDSGDPFHIRLKSHYAHKADIAREALAWIEEGMTIALDAS
                     STCWYLARQLPDIPIQVFTNSHPICQELGKRERIALISSGGQLERKYGCYVNPSLISQ
                     LKSLDIDLFIFSCEGIDGGGDLWDSNAINADFKSILLRRASQSLLLIDKSKFNRSGEA
                     RIGHLDDVTHIVSDAPQS"
     gene            complement(5907..6329)
                     /gene="fucU"
                     /locus_tag="OPV72_003395"
     CDS             complement(5907..6329)
                     /gene="fucU"
                     /locus_tag="OPV72_003395"
                     /EC_number="5.1.3.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose mutarotase"
                     /protein_id="HCR9915603.1"
                     /translation="MLKTISPLISPTLLKVLAEMGHGDEIIFSDAHFPAHSLGPQVIR
                     ADGLSVSDLLRAIIPLFELDSYAPPLVMMAAVEGDTLDPSVEARYRDALSLEAPCPDI
                     VRIDRYAFYERAQKAFAIVITGECAKYGNILLKKGVTP"
     gene            complement(6331..7749)
                     /gene="fucK"
                     /locus_tag="OPV72_003396"
     CDS             complement(6331..7749)
                     /gene="fucK"
                     /locus_tag="OPV72_003396"
                     /EC_number="2.7.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculokinase"
                     /protein_id="HCR9915604.1"
                     /translation="MKQDVILVLDCGATNVRAIAVDRQGKIVARASTANASDIAAENS
                     AWHQWSLDAILQRFADCCKSLSSALSECVVRGITVTTFGVDGALVDAQGKLLYPVISW
                     KCPRTAAVMETIERFISPRQLQTLSGVGAFSFNTLYKLVWLKENHPRLLEQAHCWLFI
                     SSLINHRLTGEFTTDITMAGTSQLLDIHQRDFSPEILQATGLARRLFPRIVEAGAPIG
                     TLQTDAARLLGLPAGVPVISAEHDTQFALFGAGAQQGEPVLSSGTWEILMVRSGQVDT
                     SLLSQYPGSTCELDSQSGLYNPGMQWLASGVLEWVRKLLWTPETPWQTLIDEARAIPA
                     GAEGVRMQCDLLACQNAGWQGVTLNTTRGHFYRAALEGLTAQLQRNLRTLEKIGHFNA
                     TELLLVGGGSRNALWNQIKANQLDIPIKVLDDAETTVAGAAMFGWYGVGEFSSPEQAR
                     AQVNYQYRYFWPQTEPEIIEGV"
     gene            complement(7895..9625)
                     /gene="fucI"
                     /locus_tag="OPV72_003397"
     CDS             complement(7895..9625)
                     /gene="fucI"
                     /locus_tag="OPV72_003397"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HCR9915605.1"
                     /translation="MKKISLPKIGIRPVIDGRRMGVRESLEEQTMNMAKATAALITEK
                     IRHACGAQVECVIADTCIAGMAESAACEEKFSSQNVGVTITVTPCWCYGSETIDMDPM
                     RPKAIWGFNGTERPGAVYLAAALAAHSQKGIPAFSIYGHDVQDADDTSIPADVEEKLL
                     RFARAGLAVASMKGKSYLSVGGVSMGIAGSIVDHNFFESWLGMKVQAVDMTELRRRID
                     QKIYDEAELEMALAWADKNFRYGEDQNASQYKRNEAQNRAVLKESLLMAMCIRDMMQG
                     NKTLADKGLVEESLGYNAIAAGFQGQRHWTDQYPNGDTAEALLNSSFDWNGVREPFVV
                     ATENDSLNGVAMLFGHQLTGTAQIFADVRTYWSPEAVERVTGQALSALAEHGIIHLIN
                     SGSAALDGACKQRDSEGKPTMKPHWEISQQEADACLAATEWCPAIHEYFRGGGYSSRF
                     LTEGGVPFTMTRVNIIKGLGPVLQIAEGWSVELPKAMHDQLDARTNSTWPTTWFAPRL
                     IGKGPFTDVYSVMANWGANHGVLTIGHVGADFITLAAMLRIPVCMHNVEEAKIYRPSA
                     WAAHGMDIEG"
     gene            complement(9657..10973)
                     /gene="fucP"
                     /locus_tag="OPV72_003398"
     CDS             complement(9657..10973)
                     /gene="fucP"
                     /locus_tag="OPV72_003398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose:H+ symporter permease"
                     /protein_id="HCR9915606.1"
                     /translation="MGNTTIQTQSFRAVDAEQSKSKRYIIPFALLCSLFFLWAVANNL
                     NDILLPQFQQAFTLTNFQAGLIQSAFYFGYFVIPIPAGILMKKLSYKAGIITGLFLYA
                     FGAALFWPAAEIMNYTLFLIGLFIIAAGLGCLETAANPFVTALGPESGGHFRLNLAQT
                     FNSFGAIIAVVFGQSLILSNVPHQSQEALDKMTPDQLSAYKHSLVLSVQTPYMIIVAI
                     VLVVALLIMLTKFPALQSDDHSDAKQSSFLSSLSRLIRIRHWRWAVLAQFCYVGAQTA
                     CWSYLIRYAIEEIPGMTPGFAANYLTGTMVCFFIGRFTGTWLISRFAPHKVLAAYALL
                     AMLLCLISAFSGGHIGLLALTLCSAFMSIQYPTIFSLGIKNLGQDTKYGSSFIVMTII
                     GGGIVTPVMGFVSDAAGKIPTAELVPALCFAVIFIFARFRSQAATN"
BASE COUNT         2659 a         2978 c         3090 g         2653 t
ORIGIN      
        1 cgtatgaatt ttccagttct cctgctacgc tacatcgagt ggttttattt actctaaaat
       61 cttcacgcca ttttaacatg gattctaaca ttgtaatttc attgtgatag ctgataaaaa
      121 tcaaaagaat gtttatcagg gaaatctgat gccgaaacta ataaagtgac tggattattt
      181 tatctgcatc gcctgaccgc cgcggacggc gctgtcaggc gacagaatat ttacgctatt
      241 tcaaccctta tgcgttgcgg caacaatcgc ttcgctcagc gcgttcagcc cctgactgcg
      301 tgaggcgcta agctgggcgc gtaaacccag ctcatcaaac agcgccagcg gtgaacgagc
      361 ctgcaactcg gcggcgtttt ttccttccac cgcggtgagc aataccgcta gcaggccgcg
      421 gacaatccgc ccctcactgt cgccgaaaaa gtgcatcgtt ccgttatctg atcgggtaaa
      481 gcccagccag acgcggttct cgcagccggc tatctccttc gcctgcgctt tgcattcatc
      541 cggcagagcg gggagctgtt ttcctaacag aatcaactga cgatatttat cctcccattg
      601 ggtcagcggg agaaagatag cgcgtaacgt ctcttccgtt accgttgtgc cgaacgggtg
      661 tccggtataa agagggtttg tcattaatcc accagcagtt ccagcgcgcg gtcaacggcg
      721 ttaaccaacg catccacatc atgttgggta ttatacggcg caaaagaggc gcgcagagtc
      781 cctgtgacgc caagttccgc tagcaatggc tgggcgcaat gttgcccggc ccggagcgca
      841 ataccgtatt ccgccagcag cgtcaccata tcgccgtggt gcacgccgac aaaatcaaag
      901 gccagcaggc tggagtcctg gcagcggaac gaacgaaagc ccggacgttt cgccagtgcg
      961 tcttccgcca gcgtcgccag cccccggctc cagttttcgg cctgttcaat atcgatatcg
     1021 gacagccatt ccagcgcagc gctcaggccg atgaccccgg cgacgttcgg cgtccccgct
     1081 tccagtttcc agggagcgct ttgagtggtg aagccttcaa agctaacgtc acggatcatc
     1141 ttgccgccgc cgagccaggg cgacatcgcc tcaagaagct ccggcttacc gtacagcacg
     1201 ccgataccgg tcgggccata cagtttgtga gcggaaaaag cataaaaatc gatatcaagc
     1261 tgctggacat ccgccgggaa gtgtacagcg ccttgcgcgc catctatcat cacgaccatt
     1321 cccgccgcgt gagcggcgct gatagcgcct gtgagatccg gacagccgcc cgttacgttc
     1381 gacatttgcc ccagcgccag tatccggctg cgcgacgtga tcagttccgg cagacgctca
     1441 acatcaggaa gacgtcggtc attaagcggc agttttatga cctgcgcgcc ggtttgttgc
     1501 gccaccatca gccagggaac aaggttggcg tgatgctcgg cgacgctaac gataatttca
     1561 tcgccggggc gcagacgagg acgggcgtaa cactgcgcca ccatgttgat cgcttcggtg
     1621 gtgccgcgtg tccagacgat acttttttca tcgggcgcgt ttaacagccg cgccgctttt
     1681 gctctggccg cttcatattg cgccgtcagg cgctgcgcct gcgcaaactg gctacgatga
     1741 acgttaccgg cgctcaaaca ataaaactgg tgcgtggcgt caatgactgc ctgtggcttt
     1801 aatgccgtgg cggcgctatc gagataaaca cccgcatcgg ctagcgcggg aaactgcgcg
     1861 cgaaactgcg tgggattaaa agcgttcatg atattcctcg gttcagttta ccgatcgtgg
     1921 cgtaaaagcg cggctgatac aaggtttgtc ctaaccatcg gaatcgtctg tatatcctgg
     1981 cgaattatgt aaaggaggtt atgctgaata atgttaggcg aatgtttaag cctgttacgg
     2041 agtccgcttt aaatagcaca aacagcttta aggagaagaa gatgaaaaag actgccgcaa
     2101 ttatctctgc atgtatgctg acttttgccc tgagcgcctg ttccggtcct aattacgtta
     2161 tgcacaccaa tgatggacgt agcattgtga ccgacggtaa accccagacc gataacgata
     2221 ccggtatgat ttcgtataaa gacgctaatg gcaacaaaca gcagatcaat cgtactgacg
     2281 tgaaagagat ggtggctctg gaaaactaac cgtttgttat acaaaaaaaa gcaccgcaat
     2341 atggcggtgc tacattaatc actatggaca gacagggtaa atgtacagga agtgaaaaag
     2401 ggtagtctcg ctaccgtggt ctgaatcgca gaccaattgc aaacacaaca acacaacatc
     2461 acaaccgtaa gccaaaagcc catcagaaca cgcattccga taaaactttt cgttccggct
     2521 caggaagtgc cgccactata ggtatttgct ggtagaacct caacggacaa tttataatgt
     2581 ctcagattaa aaaaactaat aggttaccta ttgttaccta tttgttaaat tcattcaaca
     2641 ttaagtccag aggccatgtc aaaacgatta cctcctttaa atgcgttacg cgtttttgat
     2701 gctgccgcgc gccatttgag ttttacgcga gcagcggaag aactttttgt gacgcaggcc
     2761 gcagtaagcc accaaattaa gtcacttgag gattttttgg ggctaaaact gttccgccgc
     2821 cgcaatcgtt cgctgctgct gacggaagaa ggccaaagct attttcttga tattaaagag
     2881 atattttccc agctaacgga agcaacgcgt aagctccagg cgcgcagtgc caaaggggcg
     2941 ctgacggtga gtttaccgcc cagttttgcc atccagtggc tggtgcccag gctctccagc
     3001 tttaactcag cttatccggg aattgacgtt cggatacaag ccgttgatcg tcaggaagat
     3061 aaactggcag acgatgtcga tgtcgcgatt ttttatggcc ggggaaactg gccgggcttg
     3121 cgcgtcgaaa aattatacgc agaatattta ttgcccgtct gttctccttt attgctcaca
     3181 ggcgaaaaac cgttaaaaac gccggaggat ctggcgaaac atacgttatt gcacgatgcc
     3241 tcccggcgtg actggcaggc ctatactcgt cagttagggc tcaaccatat taacgttcag
     3301 caagggccga tatttagcca cagcgcgatg gtgctacagg cggctattca cggacagggg
     3361 atcgcgctgg cgaataatgt tatggcgcag tcggaaattg aagccgggcg actggtgtgt
     3421 ccatttaacg atgttctggt gagtaagaat gctttttatc tggtttgtca tgacagccag
     3481 gcagaactgg gtaaaatagc cgccttccgt cagtggattt tggcgaaggc ggcgacggag
     3541 caagaaaaat tccgttttcg ttacgaacaa taattaactt agggtatgac catgaccagc
     3601 cgttttatgc tgattgtcgc cgctatcagc ggttttattt acgttgctct gggcgcgttc
     3661 ggggcgcatg ttttgagtaa aaccctgggc gtggttgaaa tgggctggat tcagaccggc
     3721 ctgcaatatc aggcgttcca tacgctggcg atctttggcc tggcggtggc gatgcagcgc
     3781 cgtatcagca tctggtttta ctggagcagc gtttttctgg cgctgggcac ggtgctgttt
     3841 agcggcagcc tgtactgcct tgcgctttcg catctgcgcc tgtgggcgta tatcacgcct
     3901 gtcggcggcg tcagtttcct ggtgggctgg gcgctattgc tgattggcgc cattcgtatg
     3961 aaacgtaagg gcgcgagcca tgaataaagt tgtcttgctc tgccgtccgg ggtttgaaaa
     4021 agagtgcgct gcagaaatta ccgataaagc gggaaaacgg gaaatatttg gttttgcacg
     4081 cgtaaaagag aacgcaggct atgtcattta tgaatgctac cagccggaag atggcgaaaa
     4141 gctgatttca gaactgccgt tcagttcgct gattttcgcc cgccagtggt ttgtggtggg
     4201 tgaactgctg caacatttac cgccggaaga cagaatcacg ccgattgtcg gcatgttgca
     4261 gggcgtagtg gaaaagggcg gcgagctgcg ggttgaagtc gccgacacca atgaaagtaa
     4321 agaactgatg aagttctgcc gcaaatttac ggtgccgctg cgcgcggctt tgcgtgatgc
     4381 gggcgtattg acgaattatg aaacgccgaa gcgtccggtc gttcatgtct tttttatcgc
     4441 gccaggatgc tgctataccg gttattcgtt cgcgcataac aattcaccgt tttatatggg
     4501 catcccgcgt ttgaagtttc cgtctgatgc gccgagccgc tcaacgctga aactggaaga
     4561 ggcgctccac gttttcatcc cggaagatga gtgggatgaa cgtctggcaa acggcatgta
     4621 cgcggtggat ttgggcgcct gtcccggcgg atggacgtac cagttagtga agcgcaatat
     4681 gtgggtctac tccgtagata acggcccgat ggcgcaaagc ctgatggaca ccggacaggt
     4741 gacctggttg cgtgaggatg gcttcaggta ccgtccgaac cggaataata tttcatggat
     4801 ggtctgcgat atggtggaga agccggccaa agtcaccgcg ttaatggcgc agtggctggt
     4861 gaacggctgg tgtcgggaga cgatttttaa ccttaaactg ccgatgaaaa aacgctatga
     4921 agaggtatcg cataacctgg cgtatcttca ggcgcagttg gatgagcatg gcgttaatgc
     4981 gcagatccag gcgcgtcagc tttatcacga tcgcgaagaa gtgacggtac acgtgcgtcg
     5041 gttgtgggcg gctgttggcg gacgtcgcga cgagcgataa aaacgcgctg ccgtcatccg
     5101 gcgcgtcatc agcgccggat ggcgcacgct tatccggcct atgactgcgg cgcatctgaa
     5161 acgatatgcg tcacatcatc cagatggccg atgcgcgcct ctcctgaacg attaaattta
     5221 cttttatcaa tcaataataa agactgcgag gcgcgcctga gcaggataga tttaaaatcg
     5281 gcgttgatcg cattggagtc ccacagatcg ccgccgccgt cgatcccctc gcaggaaaag
     5341 atgaacagat cgatatcaag cgattttagc tgtgagataa gcgacggatt aacgtaacag
     5401 ccatatttac gttcaagctg gccgccggaa cttatcagcg caatgcgttc gcgttttccc
     5461 agctcctgac agataggatg gctattggta aaaacctgaa tgggaatatc cggcaactgg
     5521 cgggccagat accagcaggt tgaactggca tccagcgcaa tcgtcattcc ttcttctatc
     5581 cacgctaacg cttcacgggc aatatcggct ttatgcgcat aatggctttt caggcggata
     5641 tggaatggat cgccgctgtc ctgattttca cgatgaatat atttagctcg tccgtgatta
     5701 cgcagcactt ttccctgcgt ctgtagttca ctgagatcgc ggcggatggt ctctttactg
     5761 acgttaagcc gggtggccag cgcttcggtg gtcagacttt tatgattgat cagcagatcg
     5821 actatcgctt gttggcgtgc cgctttcatt tttctcaccc catcattcga tgaacgcccg
     5881 cgtcatgcgg gcgcaccggc aagagattac ggcgttaccc ctttttttaa aagaatattt
     5941 ccgtacttcg cgcactcacc tgtgataacg atcgcaaacg ctttttgcgc ccgctcataa
     6001 aacgcatagc ggtcgatacg aacgatatcc gggcacggcg cttctaatga caaagcatcg
     6061 cgataacgcg cttcaacgct ggggtcgagc gtgtcgcctt ctacggcggc catcatcacc
     6121 agcggcgggg cgtagctatc cagctcaaag agcggaatga ttgcccgcag tagatcgctg
     6181 acgctaagac catcggcgcg aatcacctgc gggcccaggc tatgcgcggg aaagtgagcg
     6241 tcagaaaaaa tgatttcgtc cccgtggccc atctcggcca gcactttgag cagtgtcggg
     6301 gaaattaacg gtgaaatggt ttttagcatt tcatactccc tcaataattt caggttcggt
     6361 ttgcggccag aaatagcgat actgataatt gacctgcgca cgcgcctgct ccgggctact
     6421 aaattcgcct acgccgtacc agccaaacat ggcagcgccg gccacggtgg tttccgcgtc
     6481 gtccagcact ttgataggga tatcaagttg attcgcttta atttgattcc acaaagcgtt
     6541 gcgactgccg ccgccaacca gtaacagttc tgtggcgtta aaatggccga ttttctccag
     6601 cgtgcgcaga ttacgctgaa gttgcgccgt caggccttcc agcgcggcgc gatagaaatg
     6661 gccgcgggtg gtattgagcg tcacgccctg ccagcctgca ttttgacagg cgagcagatc
     6721 gcactgcatc cgcacgcctt ccgcgccagc gggaatagcg cgcgcttcgt cgatcagcgt
     6781 ttgccatggc gtttccggcg tccacagcag ttttcgtacc cattcgagta cgccggaggc
     6841 cagccactgc attccggggt tataaagccc cgactgactg tccagttcac aggtcgagcc
     6901 cggatactga ctgagcagcg aggtatccac ctgaccgctg cgcaccatca gaatctccca
     6961 tgttccggag gagagcactg gttcaccttg ctgcgcgcca gcgccgaata acgcgaactg
     7021 agtatcgtgt tcggcagaga tcactggcac acccgccggg agaccgagta gcctggccgc
     7081 gtctgtctgt agcgtgccta tcggggcgcc cgcttccacg atacgcggga acaggcggcg
     7141 cgccaggccc gtcgcctgca ggatttccgg actaaagtcg cgctgatgga tatccagtag
     7201 ctggctggtg cctgccatag tgatatcggt cgtaaactct ccggtcagac ggtggttaat
     7261 cagcgacgag ataaacagcc agcagtgagc ttgttccagc aggcgcggat gattctcttt
     7321 aagccagacc agtttataca gcgtgttaaa gctgaacgcg ccgacgccgg agagcgtctg
     7381 caattgccgg ggcgagataa agcgctcaat cgtttccatc acggcagcgg ttcgcgggca
     7441 tttccaactg atgaccgggt agagcagctt accctgcgca tcgaccagcg cgccatcgac
     7501 gccgaaagta gtcaccgtaa taccgcgaac aacacactcc gacagggcgc tggagagtga
     7561 cttgcagcag tcggcgaaac gttgcaggat ggcgtccagc gaccactgat gccaggcgct
     7621 attttctgcg gcaatgtcgc tggcgttagc ggttgaggcg cgggcgacaa ttttcccctg
     7681 gcgatcaacg gcgatcgccc gaacgttagt cgcaccgcag tcgagaacca ggataacgtc
     7741 ttgtttcata gataactcca taaacgccgc ctgatggcgc tacgcttatc cggcctacgg
     7801 ttcacgcgcc cgtaggcccg gtaagcctgc gccaccgggc taagccgcat taacgtttat
     7861 acagcgggcc ataattctgg caggcgcgat aatcctagcc ttcgatatcc ataccgtgag
     7921 ccgcccaggc ggaaggacgg tagatcttcg cctcctccac gttgtgcata cataccggga
     7981 tacgcagcat cgcggcgaga gtaataaagt ccgcccctac atgaccgatg gtgagtacgc
     8041 cgtggttagc gccccagttc gccatcaccg aatagacatc ggtaaacgga cctttgccga
     8101 taagacgcgg cgcaaaccag gtggtaggcc aggtagagtt ggtgcgggca tcaagctgat
     8161 cgtgcatcgc tttcggcagt tcgacgctcc acccctcggc gatttgcagt actggtccca
     8221 ggcctttgat gatattcacg cgggtcatgg tgaatggcac gccgccttcg gtcagaaaac
     8281 gggatgagta gccgccgccg cggaagtatt cgtgaattgc cgggcaccat tcagtggccg
     8341 ccagacacgc atccgcctct tgttggctga tttcccagtg cggtttcatg gtcggcttgc
     8401 cttcgctgtc gcgctgttta caggcaccgt ccagcgcggc agaaccggag ttaatcaggt
     8461 gaataatgcc gtgttccgcc agggcgctga gcgcctggcc ggtgacgcgt tctacggctt
     8521 ccggcgacca gtaagttcgc acgtcggcga atatctgcgc ggtaccggtg agttgatggc
     8581 caaacagcat cgctactccg ttcagactgt cattttcggt ggcgacgaca aacggttcgc
     8641 gtacgccgtt ccagtcaaaa gagctattga gcagcgcttc ggcggtatcg ccgttcgggt
     8701 attgatcggt ccagtggcgc tggccctgga agccggcggc aatggcgttg tagcccagcg
     8761 attcttcaac taaccctttg tccgccagcg tcttgttgcc ctgcatcatg tcgcgaatac
     8821 acatcgccat cagcaggctc tcttttagca ccgcgcggtt ctgggcttca ttgcgcttat
     8881 actgcgaggc gttttgatct tcgccgtagc ggaagttttt atccgcccac gccagcgcca
     8941 tctccagttc ggcctcatca taaatttttt gatcgatacg gcggcgcagt tcggtcatat
     9001 ctaccgcttg caccttcatg cccagccagg attcaaagaa gttatgatcg acaatggaac
     9061 ccgcgatccc catcgacacg ccgccgacgg agaggtagct tttgcctttc atgctggcta
     9121 ccgctaaccc tgcccgcgca aaacgcagca gtttttcttc gacgtcggca ggaatggagg
     9181 tatcgtcggc atcctgcacg tcatggccat aaatggagaa cgccggaatg cctttttggc
     9241 tgtgcgccgc cagcgccgcg gcaaggtaaa ccgccccggg acgctctgtg ccgttaaagc
     9301 cccagatggc tttcggacgc atcgggtcca tatcaatggt ttcgctgcca tagcaccagc
     9361 acggcgtaac ggtaatggtc acgcccacgt tctggctact gaatttttct tcacaggcgg
     9421 cggattccgc cattccggca atacaggtat ccgcaatgac gcactccacc tgtgccccac
     9481 aggcgtggcg gattttctcg gtgatgagcg ccgccgtcgc tttcgccatg ttcatggttt
     9541 gctcttcgag cgactcgcgt acgcccatac gacgtccatc aatcaccggg cggataccga
     9601 ttttcggtaa gctgattttt ttcatgacag attcctcacg ttattcggat aaatgttcag
     9661 tttgtcgccg cttgtgaacg gaaacgggca aaaatgaaga tgacggcaaa gcacaatgcc
     9721 ggaaccagtt cggcggtcgg gattttgcct gcggcgtcgc taacgaagcc cattactggc
     9781 gtgacaatac cgccgccaat aatggtcatg acgataaaag acgagccgta cttagtgtcc
     9841 tgtcccagat ttttgatacc cagcgagaag atggttgggt actggattga cataaatgcg
     9901 ctacacaacg tcagcgccag caggccgata tgtccgccgc taaaggcgga aatcagacac
     9961 aggagcatgg caagcagggc ataggcggcc agcactttat gcggcgcgaa gcggctgata
    10021 agccaggtcc cggtgaaacg gccgataaag aagcacacca tcgtgccggt caggtagttg
    10081 gcggcgaaac cgggcgtcat tccagggatc tcctcaatgg cgtagcggat cagatagctc
    10141 cagcaggcgg tttgcgcccc cacgtagcag aactgcgcca gcaccgccca gcgccagtgg
    10201 cggatacgga tgagtcggga gagagaagat aagaaagagc tttgtttagc atcgctatga
    10261 tcgtcacttt gcagggccgg aaatttggtc agcataatca gcagcgcaac tactaatacg
    10321 atggcgacga taatcatgta tggcgtttgt accgataaca ccaggctgtg tttataggcg
    10381 ctaagctgat ccggcgtcat tttatcaagc gcttcttgtg attgatgcgg cacgttagac
    10441 aaaataaggc tttgcccaaa cacaacggcg ataatagcgc caaaggagtt aaaagtttgc
    10501 gccagattaa gccggaaatg tccgccgctt tctggaccta atgccgtcac aaaaggattg
    10561 gccgcagttt caaggcagcc taaaccggcg gcgatgataa acaggccaat taaaaataat
    10621 gtgtaattca ttatctcggc ggcaggccag aataatgcgg cgccaaaagc atacaaaaaa
    10681 agtccagtga taatccctgc tttataactg agttttttca tcaaaatccc agcgggaatt
    10741 ggaatgacga aataaccgaa ataaaaggct gactgaataa gtccggcctg gaagttagtt
    10801 agcgtaaaag cttgttgaaa ctgcggtaat aaaatgtcat tcagattatt ggcgacggcc
    10861 cacagaaaaa atagcgagca aagtaaggcg aatggaataa tgtagcgctt gcttttgctt
    10921 tgctctgcat ccacagcacg aaaactctgt gtttgtattg ttgtgtttcc catagcatcc
    10981 tcatcggttc agaagctttt gcgtgcggtc ggttctggtc accagaccgt aaaattaggt
    11041 gagttcgctt ttcttaccgg taataaattg gcgtccggaa tgaactcatg gagtcatttt
    11101 caaataaaaa aggcctttta atatgatggc ggtcacattt atacctgaga gcatagcgtt
    11161 ctgtgattat catcacttta attttcataa aaaaatgacc gtttgagatg tttaatttaa
    11221 aaaaccacag gctgaatgcc cgaattaaat tattgctacg aaaacggtca gtggtaactt
    11281 atttttcatc tttgcccgtt ttgaaaaata ttattaagag cgggcattta tcggcgagag
    11341 aaatggcagt cgtctggttt atcgtggcga attaattgat
//
LOCUS       DAJVBX010000156        11294 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.156, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000156 DAJVBX010000000
VERSION     DAJVBX010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 11294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11294
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.156"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..209
                     /locus_tag="OPV72_003399"
     CDS             <1..209
                     /locus_tag="OPV72_003399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF2628 domain-containing protein"
                     /protein_id="HCR9915607.1"
                     /translation="FFFSWIYLFVLGLWKKAIIVILLGIVAIFIGALIGVNILGLVVA
                     AYVGVNTNKWFYEKEVKGINTWSL"
     gene            complement(258..1208)
                     /gene="corA"
                     /locus_tag="OPV72_003400"
     CDS             complement(258..1208)
                     /gene="corA"
                     /locus_tag="OPV72_003400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium/cobalt transporter CorA"
                     /protein_id="HCR9915608.1"
                     /translation="MLSAFQLEKNRLTRLEVEESQSLIDAVWVDLVEPDDDERLRVQS
                     ELGQSLATRPELEDIEASARFFEDEDGLHIHSFFFFEDAEDHAGNSTVAFTIRDGRLF
                     TLRERELPAFRLYRMRARSQAMVDGNAYELLLDLFETKIEQLADEIENIYSDLEKLSR
                     VIMEGHQGDEYDEALSTLAELEDIGWKVRLCLMDTQRALNFLVRKARLPGGQLEQARE
                     ILRDIESLLPHNESLFQKVNFLMQAAMGFINIEQNRIIKIFSVVSVVFLPPTLVASSY
                     GMNFEFMPELKWSFGYPGAIIFMILAGLAPYLYFKRKNWL"
     gene            complement(1680..3842)
                     /gene="uvrD"
                     /locus_tag="OPV72_003401"
                     /gene_synonym="mutU"
                     /gene_synonym="recL"
     CDS             complement(1680..3842)
                     /gene="uvrD"
                     /locus_tag="OPV72_003401"
                     /gene_synonym="mutU"
                     /gene_synonym="recL"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase II"
                     /protein_id="HCR9915609.1"
                     /translation="MDVSYLLDSLNDKQREAVAAPRSNMLVLAGAGSGKTRVLVHRIA
                     WLLSVENNSPYSIMAVTFTNKAAAEMRHRIGQLMGTSQGGMWVGTFHGLAHRLLRAHH
                     MDANLPQDFQILDSEDQMRLLKRLIKAMNLDEKQWPPRQAMWYINSQKDEGLRPHHIQ
                     SYGNPVEQTWQKVYQAYQEACDRAGLVDFAELLLRAHELWLNKPHILQHYRERFTNIL
                     VDEFQDTNNIQYAWVRLLAGDTGKVMIVGDDDQSIYGWRGAQVENIQRFLNDFPGAQT
                     IRLEQNYRSTSNILSVANALIENNNGRLGKKLWTDGVDGEPISLYCAFNELDEARFVV
                     NRIKTWQDNGGALAQCAILYRSNAQSRVLEEALLQASMPYRIYGGMRFFERQEIKDAL
                     SYLRLIANRNDDAAFERVVNTPTRGIGDRTLDVVRQTSRDRQLTLWQACRELLQEKAL
                     AGRAASALQRFMELIDALAQETADMPLHVQTDRVIKDSGLRTMYEQEKGEKGQTRIEN
                     LEELVTATRQFSYNDEDEDLMPLQAFLSHAALEAGEGQADTWQDAVQLMTLHSAKGLE
                     FPQVFIVGMEEGMFPSQMSLDEGWRLEEERRLAYVGVTRAMQKLTLTYAETRRLYGKE
                     VYHRPSRFIGELPEECVEEVRLRATVSRPVSHQRMGTPLAENDTGYKLGQRVRHAKFG
                     EGTIVNLEGSGEHSRLQVAFQGQGIKWLVAAYAKLETV"
     gene            complement(3978..4694)
                     /gene="yigB"
                     /locus_tag="OPV72_003402"
     CDS             complement(3978..4694)
                     /gene="yigB"
                     /locus_tag="OPV72_003402"
                     /EC_number="3.1.3.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-amino-6-(5-phospho-D-ribitylamino)uracil
                     phosphatase YigB"
                     /protein_id="HCR9915610.1"
                     /translation="MRFYRPLGRIAALTFDLDDTLYDNRPVILRTEQEALAFMQNYHP
                     SLRSFQNVDLQRIRQAVREAEPEIYHDVTRWRHRAIEQAMRDAGLSAQESIAGANAAM
                     MHFAKWRSQIEVPQATHETLQQLAKKWPLVAITNGNAQPELFGLGDYFKFVLRAGPDG
                     RSKPFSDMYFLAAEKLHVPIGEILHVGDDLTTDVAGAIRCGMQACWIKPENADLMRTQ
                     DSRLLPHIEISRLASLTSLI"
     gene            complement(4694..5596)
                     /gene="xerC"
                     /locus_tag="OPV72_003403"
     CDS             complement(4694..5596)
                     /gene="xerC"
                     /locus_tag="OPV72_003403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HCR9915611.1"
                     /translation="MTEVALSLDVSRFLRYLGVERQLSPITLQNYQRQLDAIIALAGE
                     TGLKSWQQCDAAIVRSFAVRSRRKGLGPASLALRLSALRSFFDWLVSQGELKANPAKG
                     VSAPKAPRHLPKNIDVDDVNRLLDIDLNDPLAVRDRAMLEVMYGAGLRLSELVGLDIK
                     HLDLDTGEVWVMGKGSKERRLPIGRNAVTWIEHWLDLRGLFASDEEALFLSKLGKRIS
                     ARNVQKRFAEWGIKQGLNSHVHPHKLRHSFATHMLESSGDLRGVQELLGHANLSTTQI
                     YTHLDFQHLASVYDAAHPRAKRGK"
     gene            complement(5593..6300)
                     /locus_tag="OPV72_003404"
     CDS             complement(5593..6300)
                     /locus_tag="OPV72_003404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF484 domain-containing protein"
                     /protein_id="HCR9915612.1"
                     /translation="MKQPEEELQETLTELDDRAVVDYLRHHPEFFIRNAHAVEAMRVP
                     HPVRGTVSLVEWHMARARNHINVLEENMTLLMEQAHANESLFYRLLHLQSRLVAADSL
                     DEMLMRFHRWARDLGLAGATLRLFPDRWRLGAPSRYTHLALNRQAFEPLRIQRLGQSQ
                     HYLGPLNGPELLVVLPEAKAVGSVAMSMMGSDGDLGVILFSSRDPHHYQPGQGTQLLQ
                     EIALMLPELLERWIKRV"
     gene            complement(6297..7121)
                     /gene="dapF"
                     /locus_tag="OPV72_003405"
     CDS             complement(6297..7121)
                     /gene="dapF"
                     /locus_tag="OPV72_003405"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HCR9915613.1"
                     /translation="MQFSKMHGLGNDFMVVDAVTQNVFFSPELIRRLSDRHLGVGFDQ
                     LLVVEPPYDPELDFHYRIFNADGSEVSQCGNGARCFARFVRLKGLTNKRDIRVSTANG
                     RMVLSVTEDELVRVNMGEPNFEPAQVPFRANKAEKTYIMRAAEQTILCGVVSMGNPHC
                     VIQVDNVDTAAVETLGPVLESHERFPERANIGFMQVVRREHIRLRVYERGAGETRACG
                     SGACAAVAVGIQQGLLAEEVRVELPGGRLDIAWKGPGHPLYMTGPAAHIYDGFIHL"
     gene            complement(7158..7361)
                     /locus_tag="OPV72_003406"
     CDS             complement(7158..7361)
                     /locus_tag="OPV72_003406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCR9915614.1"
                     /translation="MKNVFKTLAVLLTLFSLTGCGLKGPLYFPPADKNAPPPTKKVDS
                     QTQSTMPDKNDRATGDGPSQVNY"
     gene            7547..9556
                     /locus_tag="OPV72_003407"
     CDS             7547..9556
                     /locus_tag="OPV72_003407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915615.1"
                     /translation="MQYRNLFCLFSLSLLLPPAWGCRLSEPPHNVYQRQGSGVVYLQP
                     EEENNLSLPEVNFKRLRRLPNSLINPATQDEWDREPPLTDLTTDYVHTSAQAIFPRFS
                     YYSDGRVILYGGKIMRNPPGTPSVDVASFRAFGKVGVDKNSLYDEGKRTDDNGGENRV
                     NLQSLRKVEFSSQWKPDLLGLTLRDDRFLYVDGHRLSDPDSFTVLAQKSWDQRGKFSA
                     TFNPCIAVPFGPWDTLARTRTKIIINGDQLDADPDTFSVVRWMPGSLLTWRDKNGLHR
                     HVLNQNNLNWDMQIEKHCDAFNLQEKRVLWRKGPGCKFAEIPGLDPEQFHPLSNAVAQ
                     SQDRLYAIRKTEFGENQLDVVTLDNPNLVIDKRFNAGRYHGYLLTKTRSDFKEEDGLQ
                     VFESAGPLILMDYHVPDETEAHLGDSPHYKKWYARDDRYVYAFDGAQLWRYPTPNPKA
                     LRMKWQTTHSGYGYWVDYRIAQLDGALMEDGSFIATGIPRDPSVKTAYVKTDGTFDIG
                     KTAVRWRKVLSPDGEWGRWQTIPNVDPSQFHLVNDRIAQYKDRLYIARLSPFGEDQLE
                     TLELDSTAPFLNQKINAGKEHGYFMHNSQQAQDIQVFSINGPLKVTERFAYDNRYVYT
                     WIGSQIYRTASLCPDKTLNLNQNMYSDNKDIIIITQAQECQKSRR"
     gene            9535..9924
                     /locus_tag="OPV72_003408"
     CDS             9535..9924
                     /locus_tag="OPV72_003408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 family protein"
                     /protein_id="HCR9915616.1"
                     /translation="MPKITSLSRFARLIKHLKNALRGVGIGSCIYVIVESVMHGTING
                     VEAAGVLTISAVLGLLSALLDIKAKPRAPLILLHFLLCGGCVALMVAMLSVLNHFPVN
                     ASVILITSALFIVIYLPLGFILYRSQR"
     gene            9994..10314
                     /gene="cyaY"
                     /locus_tag="OPV72_003409"
     CDS             9994..10314
                     /gene="cyaY"
                     /locus_tag="OPV72_003409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000999950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron donor protein CyaY"
                     /protein_id="HCR9915617.1"
                     /translation="MNDSEFHRLADALWLTIEERLDNWDGDSDIDCEINGGVLTLSFE
                     NGSKIIINRQEPLHQVWLATKQGGYHFDLKGDEWVCDRSGETFWDLLEQAATQQAGEK
                     VSFR"
     gene            complement(10386..10748)
                     /locus_tag="OPV72_003410"
     CDS             complement(10386..10748)
                     /locus_tag="OPV72_003410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915618.1"
                     /translation="MFFVITHHIDVLPLATLPTHETCPYCNNQDVWLIIRQKRTRTCG
                     LSQARKRDKFGLAICNHCSNEIKEKRWSPALRQLFTEQKSLFNLTFWQRYGFWVGWLS
                     VWPALFLATWLYFTFRGW"
     gene            complement(10760..11275)
                     /locus_tag="OPV72_003411"
     CDS             complement(10760..11275)
                     /locus_tag="OPV72_003411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915619.1"
                     /translation="MSINNPILIYVNKKRQIKLALFYSVLAIVFMMSLFLNYSIMLKM
                     MCVFFIILMIAGASAYWYSAFSGKPQLTLNQEGVTLHTTRLPIVYWHEIDYVGERVSD
                     NTPVLAIFVKDIELYCQRITNEKMRNNFLSLLNKHGSNRVMNISLNDLDYDSDELQDI
                     FKMAVARNLEQ"
BASE COUNT         2695 a         3111 c         2840 g         2648 t
ORIGIN      
        1 cctttttctt ctcatggatt tatttgtttg tactgggtct gtggaaaaaa gcaattatag
       61 ttattttatt agggatcgtt gcaatattta ttggagcatt aatcggcgtt aacatacttg
      121 gacttgttgt cgcagcttat gtcggcgtca atacaaataa gtggttctat gaaaaagagg
      181 ttaaaggtat caatacttgg agcctgtaac ttttcagggt ggttcagccg cagctgaatc
      241 accctggcct taatgtctta cagccagttc ttgcgcttaa agtacagata cggcgcaagc
      301 cccgccagaa tcataaagat aatcgcgcct ggataaccaa agctccactt cagttccggc
      361 ataaactcga agttcatccc atagctggaa gcgaccagcg tcggcggcag gaacaccacg
      421 gaaaccaccg agaagatttt gataatgcgg ttctgttcaa tgttgatgaa acccatcgcc
      481 gcctgcatca ggaagttcac cttctggaac agcgattcat tgtgcggtag cagagattcg
      541 atatcgcgca ggatctcacg cgcctgctcc agctgtccgc ccggtaagcg cgccttgcgc
      601 accaggaagt tcagcgcgcg ctgggtatcc atcagacaca ggcgtacctt ccagccgata
      661 tcttccagtt ccgccagcgt ggagagcgct tcgtcgtatt catcgccctg atgcccttcc
      721 ataatgacgc ggctcagttt ttccagatcg ctgtagatgt tttcgatttc atccgccaac
      781 tgttcaattt tggtttcgaa cagatcgagt agtagttcgt aagcattacc atcgaccatc
      841 gcctggctgc gggcgcgcat acgatacaaa cggaaggcgg gcagttcgcg ttcacgcagc
      901 gtaaacagac ggccatcgcg aatagtgaat gccaccgtag agttaccggc atgatcttcc
      961 gcatcttcga agaagaagaa ggagtggata tgcagtccgt cttcgtcttc aaagaagcgc
     1021 gcggatgctt cgatatcttc cagttcagga cgcgtcgcca gactctggcc cagctcagat
     1081 tgtacgcgca atcgctcgtc gtcgtccggt tcgaccaaat cgacccatac ggcatcaatc
     1141 aggctttgtg actcctcgac ttccagccgg gtcagtcggt ttttttccag ttgaaatgcg
     1201 ctcagcatga ccgggactcc caatgcgtaa aaatatcgga cagttcagat gggcacacag
     1261 aaacaaattg ggtttcagac cattaaacag cctgactcaa cgcgacggga aaaaatgaaa
     1321 ggtcgctgac aaccgctaag gctatcagca aaaagggata gccttaggag ttgatcctgg
     1381 atgacaggat aatgagccag tatctactgg gtgtgtccaa ggcgaatgtc ctcttagcgt
     1441 aatcgtgggc gcatgttacg ccagcaaaaa tttgccgtca acacgcaacg aaacgcgaaa
     1501 aagcaataat ttccccttat gcagaaaggt tagcagagtg agagtattta tctatgattt
     1561 cagaatatta acatcaatat atcgccggat ggcggcttcg ccttatccgg cctacaaatc
     1621 aaaatgttag ccagcgcgta ggccggataa gaggtgccat ccggcaatat gagagccggt
     1681 caaaccgttt ccagcttcgc atacgcggca accagccatt tgatcccttg cccctgaaaa
     1741 gccacctgca accggctatg ttcgccgctg ccctccaggt tgacaatagt tccctcgccg
     1801 aacttcgcat ggcgcacgcg ttggccgagt ttgtagcctg tgtcgttttc cgccagcggc
     1861 gttcccattc gttgatggct caccggacga ctgacggtgg cgcgcagacg gacctcttcc
     1921 acgcactcct ccggcaactc gccgatgaaa cgcgacgggc gatgataaac ctctttacca
     1981 tacagacggc gagtttcggc ataggttagc gtcagtttct gcatggcacg ggtaacgccg
     2041 acgtaggcca gacgacgctc ctcttccaaa cgccagccct catccagcga catctggctg
     2101 gggaacatcc cctcttccat cccgacgata aacacctgcg ggaactccag ccctttggcc
     2161 gagtgcagcg tcatcagctg taccgcatcc tgccaggtat ccgcctgccc ctcgcccgct
     2221 tccagcgccg cgtgagagag gaaggcctgc aatggcatta aatcttcatc ttcgtcgttg
     2281 tagctgaact gccgcgttgc cgtcaccagt tcctctaagt tttcgatgcg cgtctggcct
     2341 ttctcgcctt tttcttgctc atacatggtg cgcaggccgg aatctttgat cacccggtca
     2401 gtctgcacat gcagcggcat gtcggcggtt tcctgcgcca gggcgtcgat cagttccata
     2461 aagcgttgca gcgcgctggc cgcacgcccg gccagggctt tttcctgtaa caattcacgg
     2521 cacgcctgcc acaatgttag ctggcgatcg cgcgaggtct ggcgcaccac gtccagcgtg
     2581 cggtcgccga taccgcgcgt tggggtattc accacgcgtt caaaggcggc atcatcgttg
     2641 cgattggcaa tcaaacgcag ataagagagc gcatctttga tctcctggcg ttcgaagaag
     2701 cgcataccgc cgtaaatgcg gtacggcata ctggcctgta ataacgcttc ttccagcacg
     2761 cgcgactggg cgttgctgcg ataaaggatg gcgcattgcg caagcgcgcc gccgttgtcc
     2821 tgccaggttt tgatacgatt aaccacaaag cgagcttcat ccagttcgtt gaaagcgcag
     2881 tacagcgata tcggttcgcc gtcaacgccg tcagtccaca gctttttgcc cagacgcccg
     2941 ttgttgtttt caatcagggc gttcgccacg ctaagaatgt tgctggtcga gcggtaattc
     3001 tgctccagac gaatggtctg cgcgccgggg aaatcattga ggaagcgctg gatgttctct
     3061 acctgggccc cgcgccagcc gtagatcgac tggtcatcgt cgccgacaat catcacttta
     3121 ccggtatcgc ccgccagcag acgaacccag gcgtactgaa tgttgttggt atcctggaat
     3181 tcgtccacca gaatgttagt aaaccgctcg cgatagtgtt gcaggatgtg cggcttgttc
     3241 agccatagtt catgagcgcg cagcagtagc tcggcgaaat ccaccagacc agcgcgatcg
     3301 cacgcttcct gataggcctg atacaccttc tgccaggtct gttccaccgg attgccatag
     3361 ctttggatat ggtgcgggcg tagcccttcg tctttctggc tattgatgta ccacatcgcc
     3421 tgacgcggcg gccactgctt ctcatcaaga ttcatcgcct taatcaggcg tttaagcaaa
     3481 cgcatctgat cttcgctgtc gagaatctgg aaatcctgcg gcaaattagc gtccatatga
     3541 tgcgcgcgca gcaggcggtg cgccagaccg tggaacgtcc ctacccacat tccgccctgg
     3601 ctggtcccca tcaactggcc aatacgatgg cgcatttccg ccgccgcttt gttggtaaag
     3661 gtcaccgcca tgatggagta tggcgagttg ttttctacgc tcagtaacca ggcgatacgg
     3721 tgcaccagca cgcgggtttt cccgcttccc gcgcccgcca gcaccagcat gttgctacgt
     3781 ggcgcggcca ccgcttcgcg ctgtttatca ttaaggctgt cgagcaggta agaaacgtcc
     3841 attggcaccg ccgcgtaaaa acatgaaaac taaaaacgcc cggtggcgct tcgcttaccg
     3901 gggctactta tcgtagggcg gataagcata gcgccatccg ccagaataac tgggaattta
     3961 tacagaacta ctggtgatta tatcagcgag gtgagagatg ccaaccgcga aatttcgata
     4021 tgcggcagta aacggctgtc ctgcgtccgc atcaggtcgg cattttcagg tttaatccag
     4081 caggcctgca tcccacagcg aatagcgcca gccacatcgg tagtcagatc gtcgccgaca
     4141 tgcaggatct cgccgatcgg cacatgcagt ttttccgccg ccaggaaata catgtcgcta
     4201 aacggtttgg aacgtccatc cgggccggcg cgcagtacaa acttaaagta atcgccgagg
     4261 ccaaacagtt ccggctgggc attgccgtta gtgatcgcca ccagcggcca ttttttcgca
     4321 agctgctgta acgtctcatg ggtagcctgc ggaacctcaa tctggctgcg ccatttggca
     4381 aaatgcatca tcgccgcatt cgcaccggca atggactcct gcgccgataa tcccgcatcc
     4441 cgcatggcct gctctatcgc gcgatggcgc cagcgggtaa cgtcatgata gatttccggc
     4501 tccgcttcac gcaccgcctg ccgtatccgc tgtaaatcga cgttttgaaa cgaacgtagc
     4561 gacgggtgat aattttgcat aaaagcgagc gcttcctgct cagtacgcaa aatcaccgga
     4621 cggttatcat aaagggtatc atccaggtca aaggtgagcg cggcaatacg ccccaaaggc
     4681 cggtaaaaac gcattatttc ccccgtttag cgcgcggatg cgccgcgtcg tacactgaag
     4741 caagatgttg aaaatcaaga tgagtataaa tttgggtggt ggaaaggttg gcatgaccca
     4801 gcagctcttg cacgccgcgc agatcgccgc tcgattccag catatgggtc gcgaacgaat
     4861 ggcgcagctt atgtggatgc acgtggctgt ttagcccctg ctttatgccc cattcggcga
     4921 accgtttttg gacattgcgc gcggagatac gcttgccgag cttcgacagg aataacgcct
     4981 cttcatcgct ggcgaacagg ccgcgcagat ccagccagtg ctcaatccac gtcaccgcgt
     5041 tacggccaat cggcaggcgt cgctctttgc tgcctttacc cattacccac acttctccgg
     5101 tatcgagatc gaggtgcttt atatccaggc caaccagttc ggataaacgc agccccgcgc
     5161 cgtacatgac ctccagcatc gcccggtcac gtacggcgag cggatcgtta agatcgatgt
     5221 ccagcaggcg gttaacgtcg tcgacatcaa tatttttcgg cagatgacgc ggcgctttcg
     5281 gtgcggagac gcccttcgcc gggttagctt tcaattcgcc ctgactgact aaccagtcaa
     5341 aaaagcttcg caatgccgag agacgtagcg ccagactggc agggccaagc cctttacgcc
     5401 gactgcgcac cgcaaaactg cgcacaatcg cagcgtcaca ttgttgccag cttttcagcc
     5461 cggtttctcc ggctaaagcg ataatggcat caagctgacg ctggtagttc tgcagggtaa
     5521 tggggctaag ctggcgctcc acgcctaaat agcgcaggaa ccgcgagaca tccagagaaa
     5581 gcgcgacctc cgtcatacgc gtttaatcca gcgttccagc agttccggca gcatcagcgc
     5641 gatctcctgt aaaagctgcg tcccctgccc cggctgatag tggtgcgggt cacggctgct
     5701 gaagagaatc accccgaggt cgccatcgct gcccatcatc gacatggcta ccgaccctac
     5761 agccttcgcc tccggcaaga ccaccagcag ttccgggccg tttagcgggc caagataatg
     5821 ctgcgactgt cccagtcgtt gaatacgcag cggctcgaag gcctgacggt ttaaagccag
     5881 atgcgtatag cgcgatggcg cgccaagacg ccaccgatcc gggaacaaac gcagcgtcgc
     5941 gccggcaagc cccaaatcgc gcgcccagcg gtgaaaccgc atcagcatct catccagact
     6001 atccgcggcg accagacggc tttgcagatg cagcaagcga taaaacaggc tttcattggc
     6061 atgagcctgt tccatcagca gcgtcatatt ttcttcaagc acattgatgt gattacgcgc
     6121 gcgggccata tgccactcaa cgagcgaaac cgttccccgc acgggatgtg gaacacgcat
     6181 cgcttcaacg gcgtgggcgt tacggataaa aaactcaggg tggtggcgca ggtaatcgac
     6241 gaccgctcga tcgtccagtt ccgtgagcgt ttcctgtagt tcttcctctg gttgcttcat
     6301 aaatggataa atccgtcgta gatatgtgcc gccggaccag tcatgtataa cggatgaccc
     6361 ggacctttcc aggcgatatc cagccgaccg cccggtaatt ccacgcgtac ttcttcagcc
     6421 agcagcccct gctgaatccc cacggcaacg gcagcgcacg cgccgctgcc gcacgcgcgg
     6481 gtctcccctg cgccgcgttc atagactcgc agccggatat gctcacgtct tacaacctgc
     6541 ataaaaccaa tgttggcgcg ttccggaaaa cgctcatggc tttccagaac cggccccagt
     6601 gtttcaacgg ccgccgtgtc gacgttatca acctgaatga cacagtgcgg attgcccatt
     6661 gaaaccacgc cgcacagtat ggtctgttcc gccgctcgca taatatacgt cttttccgct
     6721 ttgttggcgc gaaaaggcac ctgcgcgggt tcaaagtttg gctcccccat gttcacccgc
     6781 accagttcat cttccgtgac gctcagtacc atccggccat tcgcggtact gacccgaata
     6841 tcgcgtttat tggttagccc tttcaggcga acaaatcgcg cgaaacagcg cgcgccattg
     6901 ccgcactgcg agacttcact gccgtcggcg ttgaagatgc ggtaatgaaa gtccaactca
     6961 ggatcatagg gcggctcaac caccagcagc tgatcgaacc ctacgcccaa gtgtctgtcg
     7021 gatagccgac gaatcagttc cggcgaaaaa aagacattct gcgttaccgc gtcgacgacc
     7081 ataaaatcgt tgccaaggcc atgcatttta gagaattgca tcattcactc cgttcacgcg
     7141 gggacagaaa actatcctca gtaattgacc tgggacgggc catctcccgt tgcgcgatcg
     7201 ttcttatcgg gcatcgtgga ctgcgtttgc gaatcgactt ttttcgtcgg cggcggcgca
     7261 tttttatcgg ctggcgggaa ataaagcggc cctttcaaac cgcagcccgt caggctgaac
     7321 agagtcagaa gtacagcgag tgtcttaaac acgtttttca ttatggattg cctgtaagtt
     7381 catgctttct attttctatc atcgcaggag aaggagtaaa agcaagcgtt taggggctct
     7441 ttataaaatc tgaaaagcgg cgcgttgcca tgattattgc gcatttacat caggaaacat
     7501 gctttgctca tcactttagg tttacgtacc acgtccggat gaccttatgc aatatcgtaa
     7561 tttgttttgc cttttttcgc tttcacttct gctgcctccc gcttggggat gccggctgag
     7621 tgaacctccg cacaatgttt atcaacggca aggcagcggc gtggtttatc tccagccaga
     7681 agaggagaac aatctttcgt tgccggaggt gaatttcaaa cgcctgcgtc ggttacccaa
     7741 ttcattgatt aacccggcaa ctcaggatga gtgggacagg gaaccgccgc tcaccgacct
     7801 gacgaccgat tacgttcata ccagtgcgca ggctatcttc ccgcgctttt cctactacag
     7861 cgacggacgc gttattctgt acggtggaaa aatcatgcgt aatccgccgg ggacgccatc
     7921 ggtagatgtc gcctcatttc gcgcctttgg caaagtcggc gttgataaaa atagtctcta
     7981 tgacgaaggc aaacgaacgg atgacaacgg cggcgaaaac cgcgttaatt tacagtcatt
     8041 gcgtaaggtt gaatttagca gccagtggaa accagacctg ttgggcttga cgctgcgcga
     8101 cgatcgcttt ctttatgtcg acgggcatcg cctgagcgac ccggacagtt tcaccgttct
     8161 ggcgcaaaag tcctgggatc agcgcggtaa attttccgcc acatttaatc cttgtatcgc
     8221 cgtccccttt ggtccctggg atacgctggc ccgcacacgc accaaaatca tcatcaacgg
     8281 cgaccaactg gacgccgacc cagacacctt ttccgtggtg cgctggatgc ccggttctct
     8341 attgacctgg cgcgataaaa acggcttgca ccgtcacgtt ctcaaccaga acaatctgaa
     8401 ttgggacatg caaattgaaa aacactgtga tgcgttcaac ctgcaggaaa aacgcgtgct
     8461 gtggcgtaaa ggaccgggat gcaaatttgc cgaaatcccc ggccttgacc cagaacagtt
     8521 tcatccgctc agtaatgcgg tggcgcagtc tcaggatcgg ctttatgcca tcaggaaaac
     8581 ggaattcggc gaaaaccaac tggatgtcgt cacgctggat aacccaaatc tggtaataga
     8641 caagcgtttt aatgccgggc ggtatcacgg ttatttactc actaaaacgc gatccgactt
     8701 taaggaagaa gacggattgc aggtattcga gtcggctggc ccgcttattc tgatggacta
     8761 tcacgttccg gacgagacag aagcgcatct gggcgacagc ccacattaca aaaaatggta
     8821 cgcacgcgac gatcgctatg tttacgcgtt tgatggcgct caactgtggc gctatcccac
     8881 gcccaatccc aaagctctac gcatgaaatg gcaaacaaca cactcaggat acggctattg
     8941 ggtggattac cgcatagccc agttagatgg cgctctcatg gaggatggct cttttatcgc
     9001 cacgggtatc ccgcgcgatc cttccgtaaa aacagcctat gttaaaaccg atggcacctt
     9061 tgacatcggc aaaacagcgg ttcgctggcg caaggttctg tcacctgacg gtgagtgggg
     9121 tcgttggcaa accattccca acgttgaccc gagtcagttt catctggtta acgatcgcat
     9181 cgcgcaatat aaggaccggc tatacattgc gaggctctca ccttttggcg aagaccagtt
     9241 ggaaacgctg gaactggata gcacagcccc cttcctgaac cagaaaatta acgccggaaa
     9301 agagcacggc tactttatgc ataatagcca gcaggctcag gatattcagg tctttagcat
     9361 caatgggccg ctaaaagtca ccgagcgttt tgcgtatgac aaccgctatg tttatacgtg
     9421 gattggtagc cagatttacc gaacagcatc cctctgcccg gataagacgc tcaatttgaa
     9481 tcagaatatg tactccgaca ataaagacat catcatcata acgcaggcgc aggaatgcca
     9541 aaaatcacgt cgctaagccg ttttgcgcgc ttgattaaac atttgaaaaa cgcccttcgg
     9601 ggcgtgggga tcggttcatg catttacgtc attgttgaaa gcgttatgca cggcacgata
     9661 aacggtgttg aagctgccgg agtcctgacg ataagcgcgg tactcggtct gcttagcgct
     9721 cttttggata tcaaagcaaa gccgcgcgcc cccttaatcc tgttgcattt tctcctctgc
     9781 ggcggctgcg tcgcactgat ggtggcaatg ctgtcggttc tgaaccattt cccggttaat
     9841 gcgtccgtca tacttatcac cagtgcgcta tttatcgtca tttatctacc gctgggtttt
     9901 atcctttacc gctcacaacg gtaattcgta tcggttccag aagctgacgc ttccccttat
     9961 actggcgcta tcactcaata gcgggataaa acaatgaacg acagtgaatt tcatcgcctg
    10021 gctgacgccc tgtggctcac cattgaagaa cgccttgata actgggacgg cgacagcgat
    10081 atcgactgtg aaatcaacgg cggcgtgctg accctcagct ttgagaacgg cagtaagatc
    10141 attattaacc gtcaggagcc gttgcaccag gtgtggctgg caaccaaaca gggcggctat
    10201 catttcgatc tgaaaggcga cgagtgggtt tgcgatcgca gcggcgaaac gttctgggat
    10261 ctgctggagc aggcggcgac gcagcaggcg ggtgaaaagg tgagtttccg ttaagttttc
    10321 aattccgcag gagagccaga agaatagcgc tttcctgcgt atatttaacg agatatgcgg
    10381 tcgtattacc aaccccggaa tgtgaaatac agccaggttg ccagaaacaa cgcgggccat
    10441 acactcaacc aaccaaccca aaaaccgtag cgttgccaaa aggttaggtt aaatagtgac
    10501 ttctgctcgg taaaaagttg acgtaacgct ggtgaccaac gtttttcctt gatttcattg
    10561 ctgcaatgat tgcatatcgc taaaccaaac ttatctcttt ttctcgcttg agacagacca
    10621 catgtacggg tccttttttg gcgaataatc aaccatacat cctgattatt acaataaggg
    10681 catgtttcat gtgtgggtag ggttgccaga ggcagcacat caatatggtg agtaataaca
    10741 aaaaacatat atctctaccc tattgttcca ggtttctggc aacagccatt ttaaaaatat
    10801 cctgtaactc atctgaatca taatcgagat cgtttagaga gatattcatc acgcgattac
    10861 ttccatgctt attcaataat gacagaaaat tattacgcat tttctcatta gtaattcgct
    10921 gacaataaag ctcaatatct ttgacaaaaa tggccagcac aggcgtatta tcgctaacac
    10981 gctcaccaac atagtcgatt tcatgccagt aaactattgg tagcctggtt gtgtgtaatg
    11041 ttactccctc ctggttcaac gttagctgtg gctttcctga aaaggcggag taccagtaag
    11101 cacttgcgcc tgctatcatg aggattatga aaaaaacaca catcatcttt agcataatac
    11161 tataatttag aaagaggctc atcataaaaa ctatagctaa cactgaataa aacagagcta
    11221 attttatttg tcgtttctta ttcacgtaaa taagaatagg gttgtttatt gacatataat
    11281 atccttttat aaaa
//
LOCUS       DAJVBX010000157        11247 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.157, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000157 DAJVBX010000000
VERSION     DAJVBX010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 11247)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11247)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11247
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.157"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(501..1466)
                     /gene="glk"
                     /locus_tag="OPV72_003412"
     CDS             complement(501..1466)
                     /gene="glk"
                     /locus_tag="OPV72_003412"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucokinase"
                     /protein_id="HCR9915620.1"
                     /translation="MTKYALVGDVGGTNARLALCDIASGEISQAKTYSGLDYPSLEAV
                     VRVYLDEHGVSVEDGCIAIACPITGDWVAMTNHTWAFSIAEMKKNLGFSHLEIINDFT
                     AVSMAIPMLKKEHLIQFGGGEPVDGKPIAVYGAGTGLGVAHLVHVDKRWISLPGEGGH
                     VDFAPNSEEEAMILEILRAEIGHVSAERVLSGPGLVNLYRAIVKSDNRLPENLRPKDI
                     TERALADSCIDCRRALSLFCVIMGRFGGDLALTMGTFGGVYIAGGIVPRFLEFFKASG
                     FRGGFEDKGRFKDYVHGIPVYLIVHDNPGLLGSGAHLRQTLGHIL"
     gene            1670..2905
                     /locus_tag="OPV72_003413"
     CDS             1670..2905
                     /locus_tag="OPV72_003413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion channel protein"
                     /protein_id="HCR9915621.1"
                     /translation="MFHPRARTMLLLSLPALIIGVASSLVLIASMKVASVFQQFLWQR
                     LPASIGIAYDSPFWIVGMLTLTGIVVGLIIRYSPGHAGPDPAIEPLISMPVSPSALPG
                     LLLALIIGLAGGVSLGPEHPIMTINIALAAAFGSRLFPRITALDWTILASAGTIGALF
                     GTPVAAALIFSQTLSGSNDIPMWDRLFAPLMAAAAGSLTTSLFFHPHFSLPIAHYTQM
                     RLVDIASGAIVAAIAIAAGMVAVWCLPRLHELLHRLKNPVLILGIGGFILGILGVIGG
                     PLTLFKGLDEMQQMAFSQTLGAGDYFTLAVVKLAALVIAAASGFRGGRIFPAVFIGAA
                     LGLMLHAHVEAVPAAITVSCAILGLVLVVTRDGWLSLFMAAVVVPDTNLLPLLCIVML
                     PAWLLLAGKPLLAANRHEP"
     gene            complement(2925..4577)
                     /locus_tag="OPV72_003414"
     CDS             complement(2925..4577)
                     /locus_tag="OPV72_003414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-keto acid decarboxylase family protein"
                     /protein_id="HCR9915622.1"
                     /translation="MQNPYTVADYLLDRLAGCGIGHLFGVPGDYNLQFLDHVIDHPTL
                     RWVGCANELNAAYTADGYARMSGAGALLTTFGVGELSAINGIAGSYAEYVPVLHIVGA
                     PCSAAQQRGELMHHTLGDGDFRHFYRMSQAISAASAILDEQNACFEIDRVLGEMLAAR
                     RPGYIMLPADVAKKTAIPPTEALALPVHEAQSGVETAFRYHARQCLMNSRRIALLADF
                     LAGRFGLRPLLQRWMAETPIAHATLLMGKGLFDEQHPNFVGTYSAGASSKEVRQAIED
                     ADRVICVGTRFVDTLTAGFTQQLPAERTLEIQPYASRIGETWFNLPMAQAVSTLRELC
                     LECAFAPPPTRSAGQPVRIDKGELTQESFWQTLQQCLKPGDIILVDQGTAAFGAAALS
                     LPDGAEVVVQPLWGSIGYSLPAAFGAQTACPDRRVILIIGDGAAQLTIQEMGSMLRDG
                     QAPVILLLNNDGYTVERAIHGAAQRYNDIASWNWTQIPPALNAAQQAECWRVTQAIQL
                     AEVLERLARPQRLSFIEVMLPKADLPELLRTVTRALEARNGG"
     gene            4757..5755
                     /gene="mgrA"
                     /locus_tag="OPV72_003415"
     CDS             4757..5755
                     /gene="mgrA"
                     /locus_tag="OPV72_003415"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-glyceraldehyde 3-phosphate reductase"
                     /protein_id="HCR9915623.1"
                     /translation="MIYQPDENRYHTMEYRRCGRSGVKLPAISLGLWHNFGDTTRVEN
                     SRALLQRAFDLGITHFDLANNYGPPPGSAECNFGRILQEDFLPWRDELVISTKAGYTM
                     WDGPYGDWGSRKYLIASLDQSLKRMGLEYVDIFYHHRPDPETPLKETMKALDHLVRHG
                     KALYVGISNYPADLARQAIDILEDLGTPCLIHQPKYSLFERWVEDGLLTLLQEKGVGS
                     IAFSPLAGGQLTDRYLNGIPEDSRAASGSRFLKPEQITADKLEKVRRLNELAARRGQK
                     LSQMALAWVLRNDNVTSVLIGASKPSQIEDAVGMLANRRFSAAECAEIDAILEGRF"
     gene            5869..6195
                     /locus_tag="OPV72_003416"
     CDS             5869..6195
                     /locus_tag="OPV72_003416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2502 domain-containing protein"
                     /protein_id="HCR9915624.1"
                     /translation="MFRSLILAAALLAFTPLAANAGEITLLPSIKLQIGDRDDYGNYW
                     DGGRWRDRDYWHNHYEWRKNRWWRHDNGYHRGWDKRKAYERGYREGWRDRDDHRGRGR
                     GHKHHH"
     gene            complement(6256..7497)
                     /locus_tag="OPV72_003417"
     CDS             complement(6256..7497)
                     /locus_tag="OPV72_003417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HCR9915625.1"
                     /translation="MTDNRVENSSGRAARKLRLALMGPAFIAAIGYIDPGNFATNIQA
                     GASFGYQLLWVVVWANLMAMLIQILSAKLGIATGKNLAEQIRDHYPRPVVWFYWVQAE
                     IIAMATDLAEFIGAAIGFKLILGVSLLQGAVLTGIATFLILMLQRRGQKPLEKVIGGL
                     LLFVAAAYIVELFFSQPDMAQLGKGMVIPALPNPEAVFLAAGVLGATIMPHVIYLHSS
                     LTQHLHGGTRQQRYSATKWDVAIAMTIAGFVNLAMMATAAAAFHFSGHTGIADLDQAY
                     LTLEPLLSHAAATVFGLSLVAAGLSSTVVGTLAGQVVMQGFVRFHIPLWVRRTITMLP
                     SFIVILMGLDPTRILVMSQVLLSFGIALALVPLLIFTSNATLMGELVNTRRVKQIGWI
                     IVVLVVALNIWLLVGTVMGLS"
     gene            7840..9042
                     /gene="nupC"
                     /locus_tag="OPV72_003418"
     CDS             7840..9042
                     /gene="nupC"
                     /locus_tag="OPV72_003418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside permease NupC"
                     /protein_id="HCR9915626.1"
                     /translation="MDRVLHFVLALAVVAVLALLVSSDRKKIRIRYVIQLLVIEVLLA
                     WFFLNSDVGLGFVKGFSEMFEKLLGFANEGTNFVFGSMNDQGLAFFFLKVLCPIVFIS
                     ALIGILQHIRVLPVVIRAIGFLLSKVNGMGKLESFNAVSSLILGQSENFIAYKDILGK
                     MSRNRMYTMAATAMSTVSMSIVGAYMTMLDPKYVVAALVLNMFSTFIVLSLINPYTVD
                     ASEENIQMSNLHEGQSFFEMLGEYILAGFKVAIIIAAMLIGFIALIAALNALFATVTG
                     WFGYSISFQGILGYIFYPVAWVMGVPSSEALQVGSIMATKLVSNEFVAMMDLQKIAST
                     LSPRAEGIISVFLVSFANFSSIGIIAGAIKGLNEEQGNVVSRFGLKLVYGSTLVSVLS
                     ASIAALVL"
     gene            complement(9095..>11247)
                     /locus_tag="OPV72_003419"
     CDS             complement(9095..>11247)
                     /locus_tag="OPV72_003419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sensor domain-containing phosphodiesterase"
                     /protein_id="HCR9915627.1"
                     /translation="FLLAFCLTVPAILLSRLISPRATIDSSYIFLAWLPLCVMFSVLF
                     LFGRRGVAPMVGGMMLTNEWNFHLPLPQAMVLLFCQTFPVLLVCAIVRWQLGARWRYG
                     IPNQGIWLRVFWLGLMTPFGIKISMHLAGHYLAFPVTISTFFGTGTAIFSIVDLLSLI
                     SAALIFTLFFYYPLRMIVSPHYMRIFWRRDVAPYLAKEKRLFTLLWFATLATLLAVLC
                     TPFETKYIAGYLVPVLFIGFTIGVGKISYPLLNFSWALTALFLLSYNRNFLQGVGSEY
                     SLAFILSVLISFSICLLYMARINQRSEWLNRQWHSQALTDPLTQLPNLRALGQFLLQD
                     AGQSVCYLRMENLEFLSRHYGMQMRVHCEREVFRVLQPLLLEKEKIFHLPGSELLLVL
                     TGPETEARLQYMLNVLNNRKIYWNNTGLDMEYGASWGTFDGRQETLQPLLGQLSWLAE
                     QSCSHRRVLALTQSIEAASGQTTERVLRLQKIRQALERGALVLYAQPIRDAQGKGYDE
                     ILTRLRCDDGIMMPNQFIPLIAQFNLSVRFDMQVMEALLQWLSAHPSAEQGARFSVNL
                     MPLTLLQKETASRIMQLFKRYGVPPASVIIEITEEQAFSHSEISMHNINQLRKFGLKI
                     AIDDFGTGYANYERLKRLKADIIKIDGCFVKDILTDSLDAMIVKSITDLAKAKSLSVV
                     AEFVETPAQRDLLLQLGVHSLQGYLIGRPRPLGK"
BASE COUNT         2670 a         3066 c         2922 g         2589 t
ORIGIN      
        1 cctaacgcgg tatggccgac gataatttcc tgtcaataaa ccttatctca aataatcccc
       61 ttttgatttt gtggtttttc ctctttaatc aaaagcctta ctaacgataa tggtattcgt
      121 tcatgtcata ttgcggtatt tttcagggat atttccccga aaataaggat cctttccggc
      181 aagctgccgc gatgaaagcg taaataaggc agcgaaccgg atacgtacag taaaataaat
      241 ccctgttttc gcctgagtaa tcaccatgac gtgatgactc aacgcgctgg tgtttgactt
      301 ttcgctcagc aagagtaaag tgaaataatt cagtcagttg aagtattcat acacaggaac
      361 ggcaatgaaa aaaaaccgcg tgaggcacgc ggtttgagac tgacaagaga atgtttcatt
      421 gcctgatgac gctgcgctta tcaggcctac agatgacaca cttttgtagg ccggataagg
      481 cgtttatgcc gccgtctgac ttatagaata tggcctaatg tctggcgcag atgcgcgccg
      541 gagcctaaca agccgggatt atcatggaca atcagataga ccggaatacc gtgtacataa
      601 tctttaaagc ggcctttatc ttcaaagccc ccacggaagc cagacgcttt aaagaattcc
      661 aggaagcgcg ggacaatgcc gccagcgata taaacgccgc caaatgtccc catggttaac
      721 gccagatcgc cgccaaatcg ccccatgatg acgcaaaaga gcgacaacgc gcggcgacaa
      781 tcgatacagc tatccgccag ggcgcgttcg gtaatatctt tcgggcgcag attttccggc
      841 agacggttgt cggacttaac aatcgcccgg taaagattca ccagccccgg gccagacagc
      901 acgcgctcgg cggaaacgtg gccaatttcg gcgcgcaata tttccagaat catagcttct
      961 tcttcgctat taggcgcaaa atcgacatgc ccgccttcgc ccggaaggct aatccaacgc
     1021 ttatccacat gcaccagatg cgccacgccc aagccggttc ccgcgccgta caccgcaata
     1081 ggtttgccgt ctaccggttc gccgccgccg aactgaatta aatgctcttt tttcagcatc
     1141 gggatcgcca tcgacacggc ggtgaaatcg ttgatgattt ccagatgact aaagccgaga
     1201 ttttttttca tttccgcaat agaaaaagcc caggtatggt tagtcatcgc cacccagtcg
     1261 ccggtaatcg ggcaggctat ggcgatacaa ccatcttcca cgctgacgcc atgctcatcg
     1321 agataaacgc gcaccacggc ctcaagactg gggtaatcca ggccggaata cgttttggcc
     1381 tgcgagattt ctccactggc gatatcacac agggcaagac gcgcattcgt gccgcctaca
     1441 tctcctacta aagcatactt tgtcattctt ctactactcc gctaaagtca aaataagtct
     1501 ttgtcacact gtaaattcat gggggcataa caacaacggc catcaggctg actgcctata
     1561 aatatagatc ttcatcacag aattactttc ttgtttcagc accaattgca gcaatgccgt
     1621 cgggcaggct gtgcaaaata gatatacgac cccgtgtaag gaagagatta tgttccaccc
     1681 gcgtgcccga acgatgctgc tgctgtcgct ccctgcgctg attattggcg tagcgtcaag
     1741 cctagtttta atcgcctcga tgaaagtcgc gtcggttttt cagcaatttc tttggcaacg
     1801 actgcccgcc agcatcggaa tcgcttatga ttcgccgttc tggatagtgg gtatgctcac
     1861 gctaaccggg atcgtggtgg gtttgattat ccgttacagt cccggacacg ctggccccga
     1921 tccggccatc gaaccgttaa tcagtatgcc ggtctcgcca tctgcgctgc ccgggctgct
     1981 tctcgcctta atcatcggcc ttgctggtgg ggtaagtttg gggccagagc atccgataat
     2041 gacaataaat atcgcgctgg cggcggcttt cggctcccgc ctgtttccgc gtatcacggc
     2101 gttagactgg acgattctgg cctcagcagg caccatcggc gcgctgttcg gcacgcccgt
     2161 cgccgcggcg ctgatttttt cgcaaacgct tagcggctct aacgatattc ccatgtggga
     2221 tcgcctgttt gcgccgttaa tggcggcagc ggcggggtca ctcaccacca gcctgttctt
     2281 tcatccgcat ttttcgttac ccatcgccca ttacacgcag atgcggctgg tggacattgc
     2341 cagcggagcg atcgtcgcgg cgatcgccat tgccgccggg atggtcgccg tctggtgcct
     2401 tccgcgtctg cacgagttgc tgcaccgact aaaaaatccg gtcctgattc tcggcattgg
     2461 cggttttata ctgggtattc tgggcgtcat tggcgggccg cttaccctgt ttaaaggcct
     2521 ggacgaaatg caacaaatgg cgtttagcca gacgttgggc gcgggagatt attttacctt
     2581 agccgtcgtc aaactcgccg cgctggtcat cgcggcggcg agcggctttc gcggcgggcg
     2641 catttttccg gctgtgttta tcggcgcggc gctggggctc atgctccatg cccatgttga
     2701 ggccgtaccc gcggcgatta ccgtctcctg cgcgattctt ggcttagtgc tggtagtgac
     2761 gcgcgacggc tggctcagtc tgtttatggc ggcagtcgtc gtaccggata ccaatctgct
     2821 gccgctgctc tgcattgtga tgctccccgc ctggctattg ctggcgggaa aaccgttgct
     2881 ggccgccaac cgtcacgaac cctaatccgg cgcagcgggg gccattatcc cccgttgcgg
     2941 gcttccagcg cccgggtcac ggtacgcagt aattccggca gatcggcttt tggcaacatc
     3001 acttcaataa atgacagacg ttgtgggcgc gccaaccgtt cgaggacctc tgccagttgg
     3061 atagcctgcg tcacccgcca gcactccgcc tgttgcgccg cgtttagcgc cggtggtatc
     3121 tgcgtccagt tccagctcgc gatgtcgtta taccgctggg ccgcgccgtg aatggcgcgc
     3181 tctacggtat agccgtcatt gttgagcagc aggatgaccg gcgcctgccc gtcgcgtaac
     3241 atcgagccca tctcctgaat cgtgagctgc gccgcgccat cgccaataat cagaattacc
     3301 cgccgatcgg ggcaggcggt ttgcgcgcca aacgcggcgg gcaaggaata gccgatagac
     3361 ccccacagcg gctgaaccac aacttccgcg ccgtcaggaa gcgacagcgc ggcagcgcca
     3421 aaggcggcgg tcccctggtc gacaaggata atatcgccgg gtttgagaca ctgctgtaag
     3481 gtttgccaga agctttcctg ggtcagttct cccttatcaa tccgcactgg ctgtccggcg
     3541 gaacgcgtcg gcggcggcgc aaaagcgcat tcaaggcaca gttcgcgcag cgtagacact
     3601 gcctgcgcca tcgggaggtt gaaccaggtt tcgccgatgc gcgacgcgta aggctgaatc
     3661 tccagcgtgc gttccgccgg caattgttgg gtaaatccgg ccgtaagggt atcgacaaaa
     3721 cgggtgccga cgcagataac cctatcggcg tcctctatgg cctgacgtac ttctttgctg
     3781 ctggcgcctg cactataggt gccaacgaag ttcgggtgct gttcatcaaa aagccccttc
     3841 cccatcagta gtgtcgcatg agcgatgggc gtttccgcca tccagcgctg caacagtggt
     3901 cgtaaaccaa aacgcccggc aagaaagtcg gccaatagcg caatgcgccg actgttcatc
     3961 aggcactgac gggcgtggta acgaaaagcc gtctccacgc cgctttgcgc ttcatgcacg
     4021 ggcaacgcca gcgcctccgt aggcgggata gccgtttttt tcgccacgtc ggcgggcagc
     4081 atgatgtatc ctggcctgcg tgcggcaagc atttcaccca atacgcggtc aatctcgaaa
     4141 caggcgttct gttcatccaa tattgcgctg gcagcggata tcgcctgact catgcgataa
     4201 aaatgacgaa aatcgccgtc accgagggta tggtgcatca attcgccacg ctgctgcgca
     4261 gcgctacagg gcgcgccgac gatatgcaag accgggacat attccgcgta actgcccgcg
     4321 ataccgttaa tagcgctaag ttctcccacg ccaaaggtgg tgagtagcgc tccagcgccc
     4381 gacatgcgcg cataaccgtc cgcggtataa gcggcgttca gctcattggc gcatcccacc
     4441 caacgcaagg tcgggtggtc aatcacatgg tcaagaaact gcaagttata atcgcccggt
     4501 acgccaaaaa gatggccaat gccgcatcct gccagtctgt ccagcaaata gtcggccacg
     4561 gtataggggt tttgcatgac agctttcctt ctgacgttga cattatgttg agtattaagg
     4621 aatgccgatg gctgtccagc acggcgggga tgaaagcctg gaaaacaatg tttacagcgg
     4681 caaacagtaa aagccggata ccgcctggcg agtgtaaccg tatacactat ttattcacgc
     4741 cacaggggga aaggtcatga tttatcagcc cgatgagaat cgttatcaca caatggagta
     4801 tcgtcgctgc gggcgcagcg gcgtcaaact tcccgctatt tcgctggggt tatggcacaa
     4861 cttcggcgat acgacacggg tagaaaatag ccgggcgctg ctgcaacgcg cgttcgatct
     4921 gggcattacc cactttgatc tcgccaataa ttatgggccg ccgccgggct ccgcagaatg
     4981 caattttggc cgcattctgc aggaagattt tttaccgtgg cgcgatgagt tagtcatctc
     5041 caccaaagcg ggctacacca tgtgggatgg cccttatggc gactggggtt cacggaaata
     5101 ccttatcgcc agcctcgatc aaagcctgaa acgtatgggg ctggagtatg tcgatatctt
     5161 ttatcaccat cgtcccgatc ccgaaacgcc gcttaaagag acgatgaaag cgttagatca
     5221 ccttgtgcgc cacggcaaag cgttgtacgt ggggatctct aactatcctg ccgatctggc
     5281 cagacaagct atcgatattc tggaggatct cggcacgcct tgcctgattc atcagcctaa
     5341 atattcgctt tttgagcgtt gggtagagga cgggctgctg acgctgttgc aggaaaaagg
     5401 cgtcggcagt attgccttct cgccgctggc gggcgggcag ctcactgacc gttatctgaa
     5461 tggcattccg gaagattccc gcgcggcgag cggaagccgt ttccttaaac cagaacagat
     5521 taccgccgac aaactggaaa aagttcgccg gttgaatgaa ctggctgcac gacggggcca
     5581 aaaattgtct cagatggcgc tcgcctgggt gctgcgtaac gataacgtta cctcggtact
     5641 gattggcgcc agcaaaccgt cgcaaatcga agacgccgta ggaatgctgg ccaatcgccg
     5701 tttttcggcg gcggaatgtg cagaaattga cgctattctg gagggccggt tttagcaaaa
     5761 aatgctctcc ttcatgattt aagagttaag gcgatgaaac aaatctttac tgctttgtaa
     5821 tattgcatta acaggccggc gacggctcga tcgtgaagga gagaaagtat gttcaggtca
     5881 ctgattctgg cggcagcctt gctggctttt acaccgcttg ccgcgaatgc gggcgaaatc
     5941 accctgttgc cctcaataaa attacagatt ggcgatcgcg atgattacgg taactactgg
     6001 gacggtggtc gctggcgcga ccgggattac tggcacaacc attatgaatg gcgtaaaaat
     6061 cgctggtggc gccatgacaa cggctatcat cgcggctggg ataagcgtaa agcgtatgaa
     6121 cgcggttatc gggaaggctg gcgcgatcgc gacgatcatc gcgggcgagg ccggggtcac
     6181 aaacatcatc actaagcctc ctgctgaata acagcccgat gacgcccacg catcgggcct
     6241 gctatctttc tgtctttatg acaaccccat caccgttcca accagcaacc agatattcag
     6301 ggcgacgacc agcacgacaa ttatccagcc aatctgtttt acccgccgcg tgttcaccag
     6361 ctcgcccatt agcgtagcgt tactggtgaa aatcaggagc ggcaccagcg ccagcgcaat
     6421 accaaaactc agcagcacct ggctcatcac cagaattcgg gtagggtcca gccccatcaa
     6481 aatcacaata aatgagggca gcatggtaat ggtgcgccgt acccacagcg gaatgtgaaa
     6541 acggacaaac ccttgcatca ccacctgccc cgccagagtc cctaccacgg tggaggaaag
     6601 ccctgccgca accagactaa gaccaaacac tgttgccgcc gcatggctta gtaacggttc
     6661 cagcgtcagg tatgcctgat cgaggtcggc gatgccagta tggccgctaa aatgaaacgc
     6721 cgccgcggcg gtcgccatca ttgccagatt gacaaaaccg gcaatcgtca tggcaatagc
     6781 gacatcccat ttcgttgctg agtaccgttg ttgccgcgtt ccgccgtgca gatgctgcgt
     6841 taatgacgag tgcagataaa tcacgtgcgg cataatcgtc gcgccaagca cgccggcggc
     6901 taagaatacg gcttccgggt tcggtagcgc cgggataacc attcctttgc cgagctgcgc
     6961 catatcaggc tgagagaaaa acagctccac aatgtaagcg gcggcgacaa aaagcagtaa
     7021 accgccgatg actttttcaa gcggtttttg accgcggcgc tgtaacatta aaatcagaaa
     7081 cgtcgcgata ccggtcaata ccgcgccctg tagtaaagag acgcccagga tcagcttaaa
     7141 acctattgcc gcgccgataa attcagctaa atcggtggcc atcgcgatga tttccgcctg
     7201 tacccagtaa aaccagacta ccggacgcgg ataatggtcg cgaatttgct ccgccaggtt
     7261 cttgccggtg gcgatcccga gttttgccga gaggatttga atcagcatcg ccatcaggtt
     7321 cgcccagacc accacccaga gtagctggta gccaaagctg gcgccggcct gaatattggt
     7381 cgcgaagtta ccgggatcga tataaccaat cgcggcaatg aacgcaggtc ccattaatgc
     7441 gagccttagc ttgcgcgccg cccgtccgct gctattctct acgcgattgt cagtcatctt
     7501 ttgcctcaaa aacatagcct ttgctatgtt tcatgctatg ttcattgata atgattatca
     7561 agtgcatttc aatgggtacg ggtgattact ttgatagtgt gaaacgatag accgatacga
     7621 tggcgacctg tatcagaaca gtttggctta acattacaag attagcacac tgatataact
     7681 tttcattttc atattcagta cagtaaaagt gtattacaga tcactaattt tgaatctcgt
     7741 cacaggtcct tattatagtg tgtgttggat ctcgttttct ttacagctgt tgcatagaat
     7801 gtgcacgaaa attaaacctg cctcatattt ggagcaaata tggaccgcgt ccttcatttt
     7861 gtcctggcgc ttgccgttgt tgcggtactc gcactgctgg ttagcagcga ccgtaaaaaa
     7921 attcgcattc gttacgtcat tcagttactt gttatcgaag tgttactggc ctggttcttc
     7981 ctgaactcgg atgttggcct tggcttcgta aaaggtttct ccgagatgtt tgaaaaactg
     8041 ctcggatttg ccaacgaagg gacaaacttc gtctttggca gtatgaacga tcaaggtttg
     8101 gcgttcttct tcctgaaagt attgtgcccg atcgtcttta tttccgcgtt gatcggtatt
     8161 ctccagcata tccgtgttct gccagtggtc atccgcgcta ttggtttcct gctatccaaa
     8221 gtaaacggta tgggcaaact ggaatctttt aacgccgtca gctcgctgat cctcggccag
     8281 tctgagaact ttatcgctta taaagatatt ctcggtaaaa tgtcccgtaa ccgcatgtac
     8341 accatggctg caacggcgat gtctaccgtt tccatgtcta tcgtgggcgc gtatatgacc
     8401 atgctggacc ctaaatatgt ggtcgcagcg ctggttctga acatgttcag cacctttatc
     8461 gttctgtcgc tgatcaaccc ctataccgtt gatgccagcg aagaaaatat tcagatgtcg
     8521 aacctgcatg aaggccaaag tttcttcgaa atgttgggcg agtacattct ggcaggtttt
     8581 aaagtggcga ttatcatcgc ggcgatgctg atcggcttca tcgcgctgat cgcggcgctg
     8641 aacgcgctgt tcgcaacggt taccggttgg ttcggctaca gcatctcctt ccagggcatt
     8701 ctgggttaca tcttctaccc ggtcgcatgg gtaatgggcg taccgtccag tgaagcgctg
     8761 caggtaggaa gtatcatggc gaccaaactg gtttccaacg aattcgtggc gatgatggat
     8821 ctgcagaaaa tcgcctctac cctctctcca cgcgctgaag gcattatctc cgtcttcctg
     8881 gtgtccttcg cgaacttctc ttccatcggt attattgcgg gcgcgattaa aggcctgaac
     8941 gaagagcaag gcaacgtggt ttcccgtttt ggtctgaaac tggtttacgg ttctacgctg
     9001 gtgagcgtac tgtccgcctc tatcgcggcg ctggtactgt aagtctgcgt ttaatgtaga
     9061 aaccggggag ctatccccgg tttttttatg ccgcttattt gcctaacggg cgcgggcggc
     9121 caatcagata tccctgcaaa ctatgtacgc caagctgcaa tagcagatcg cgctgcgcag
     9181 gcgtttcaac aaactcagcc acgacgctca acgatttcgc tttcgctaaa tcagtgatgg
     9241 atttcacgat catcgcatcc agggagtccg tcagaatatc ttttacgaaa caaccgtcga
     9301 ttttaatgat gtccgccttg aggcgtttta gccgttcata gtttgcataa ccggtgccga
     9361 aatcatcaat ggcgattttt aggccaaact tacgcagctg gttgatattg tgcatactga
     9421 tttcggaatg agagaaggcc tgttcttcag taatttcgat gatgaccgaa gcaggcggga
     9481 cgccatagcg tttaaaaagc tgcataatgc gcgacgccgt ctctttttgc agcagcgtca
     9541 gcggcatcaa attaaccgaa aaacgcgccc cctgctccgc cgaaggatgc gcggacaacc
     9601 attgcaggag cgcttccatc acctgcatat caaaccgtac gctcaggtta aactgggcga
     9661 taagcggaat gaactgattc ggcatcatga taccgtcgtc gcaccgaagc cgcgtcagaa
     9721 tctcgtcata cccttttccc tgcgcgtcgc gaatgggttg cgcatacaaa accagcgcgc
     9781 cgcgctccag cgcctgacgg attttctgca accgcagcac ccgttccgtc gtctgcccgg
     9841 aagcggcttc aatactctgg gtcagtgcaa gcacccgacg gtgcgagcag gattgctccg
     9901 ccagccagct taattgcccc aacagcggtt gcaaggtttc ctggcgacca tcgaatgttc
     9961 cccacgatgc gccgtattcc atgtccagac cggtattgtt ccagtaaatt ttgcggttat
    10021 taagcacatt gagcatatat tgcaggcggg cttccgtctc cggtcccgtc aataccagca
    10081 ataattcact gcccggcaga tggaaaattt tctccttttc cagcagcagc ggctgcaaca
    10141 cgcgaaacac ctcgcgttcg caatgcacgc gcatctgcat accgtaatga cggctcagaa
    10201 attccaggtt ttccatgcgt agataacaca cgctttgccc ggcatcctgt aaaagaaact
    10261 gccccagcgc gcgcaagtta ggcagttgcg tcaacggatc ggtcaatgcc tgcgagtgcc
    10321 actgtcgatt caaccattcg ctacgctgat taatccgcgc catgtacaac aaacaaatac
    10381 taaaagaaat gagaactgaa aggataaatg ccagcgaata ttctgaaccc acgccctgca
    10441 gaaaattgcg gttatagcta agcaggaata gcgcagtgag agcccaacta aaattcaaca
    10501 gcggatagct gattttcccc acgccgatgg taaatccaat gaacagaact ggcaccagat
    10561 agccagcaat atactttgtc tcgaaaggcg tacacagcac cgctaatagc gtcgccagag
    10621 tggcaaacca gagaagcgta aacaggcgtt tttctttggc gagataagga gcgacatccc
    10681 tccgccagaa aatacgcata tagtgcgggc tgactatcat tcgcagcgga taatagaaaa
    10741 agagggtaaa aataagcgcg gcagaaatca gactcaataa atcgacaatc gagaaaatag
    10801 cggtgccggt gccaaagaag gtagagatgg tcaccgggaa agccaggtag tgccccgcca
    10861 gatgcatact gatttttata ccaaacggcg tcattaaccc taaccagaaa acgcgtagcc
    10921 agatgccttg gttgggtatt ccgtagcgcc agcgcgcgcc cagctgccag cgtacgatag
    10981 cgcaaaccag caacacggga aacgtctggc aaaatagcag caccatcgcc tgtggcagag
    11041 gtaaatgaaa attccattca ttagtcaaca tcattccgcc taccatcggc gcgacgccac
    11101 ggcggccaaa taaaaacagc acggaaaaca tgacgcagag cggtagccag gccagaaaga
    11161 tatagctgga atcaattgtg gcgcggggag aaatgagacg agatagcaga atagccggaa
    11221 cggtcaggca gaaggccagt aagaata
//
LOCUS       DAJVBX010000158        11219 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.158, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000158 DAJVBX010000000
VERSION     DAJVBX010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 11219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11219
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.158"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            186..1736
                     /locus_tag="OPV72_003420"
     CDS             186..1736
                     /locus_tag="OPV72_003420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HCR9915628.1"
                     /translation="MTTRHLVSLVTGVLILSVLFPIGLSLWLAHRQVEKRFNEELDIF
                     SSRVALRTERVSDQAKAALTHIASFKGEPCSSAHLLAMRRVSYSFRYVQEVLYLKNSI
                     PVCSSLEKESHIPAFPPPMKITRDGYRAWFTAQNDLGIKRYMAALGSDSYIVMIDPAS
                     FIDVIPFGAWPIDVAIIGRERNTVVASSGNLDHAILPLIHHETPLRLENRGIQYAIHP
                     FPEMGITIVSWAPTAPLERSWYRQAFIWLPAGIVTGLLAAAFILRILRRLQSPRHRLQ
                     DAIDNREINVHYQPIVSLSSGKIVGAEALARWQQADGTFLSPEIFIALAEQTGLTEPL
                     TRLIIDTVFEDMGSWLKSHPEQHISINLEASDLASETLPTLLSTLLNRSQISPSQIAL
                     ELTEREFADPKTSAPIVARYRNAGHSIYIDDFGTGYSSLSYLQNLDVDVLKIDKSFVD
                     ALEYKNVTPHIIEMAKTLKLKMVAEGIETTRQEQWLRQHGVHYGQGWLYSKPLPATAF
                     ILWVEQRL"
     gene            complement(1786..1882)
                     /gene="ffs"
                     /locus_tag="OPV72_003421"
     ncRNA           complement(1786..1882)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="OPV72_003421"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            1967..2356
                     /locus_tag="OPV72_003422"
     CDS             1967..2356
                     /locus_tag="OPV72_003422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MGMT family protein"
                     /protein_id="HCR9915629.1"
                     /translation="MLVSCASGLSSPLIPDYPEALTQDSIMDIQDTFPQRVWQIVASI
                     PEGFVTTYGDVARLAGSPRAARQVGGVLKRLPEGSTLPWHRVVNRHGAISLTGPDLQR
                     QRQALLAEGVVVSGSGQIDLQRYRWVY"
     gene            complement(2389..2958)
                     /locus_tag="OPV72_003423"
     CDS             complement(2389..2958)
                     /locus_tag="OPV72_003423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaY family lipoprotein"
                     /protein_id="HCR9915630.1"
                     /translation="MKLVHIVSGLAVAISLAACADKSADIQTPAPNPNMSITANQSTI
                     QQPNVSGTVWIRQKVALPPDAVLTVTLSDASLADAPSKVLSQKAVRTEGKQAPFSFVL
                     PFNPSDIQPNARILLSAAITVDNKLVFITDSVKPVINNGGTKADLTLVPVQQTAVPVQ
                     ASGGATTTVPSTSPTQVNPSSAVPAPTQY"
     gene            3173..4033
                     /gene="tesB"
                     /locus_tag="OPV72_003424"
     CDS             3173..4033
                     /gene="tesB"
                     /locus_tag="OPV72_003424"
                     /EC_number="3.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase II"
                     /protein_id="HCR9915631.1"
                     /translation="MSQTLNNLLTLLNLEKIEEGLFRGQSEDLGLRQVFGGQVVGQAL
                     YAAKETVPEARLVHSFHSYFLRPGDSQKPIIYDVEVLRDGNSFSARRVAAIQNGKPIF
                     YMTASFQAPEPGFEHQKTMPTAVGPEGLPSETEIAQSLAHLLPPILKEKFLCDRPLEI
                     RPVEFHNPLKGHVSAPVRQVWIRANGTVPDDIRVHQYLLGYASDLNFLPVALQPHGIG
                     FLEKGIQIATIDHSMWFHRPFNFNEWLLYSVESTSASSARGFVRGEFYTQDGALVAST
                     VQEGVMRNHN"
     gene            complement(4133..5419)
                     /gene="amtB"
                     /locus_tag="OPV72_003425"
     CDS             complement(4133..5419)
                     /gene="amtB"
                     /locus_tag="OPV72_003425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter AmtB"
                     /protein_id="HCR9915632.1"
                     /translation="MKIAMIKTTLASLALLPGLTIAAPAVADKADSAFMMICTALVLF
                     MTIPGIALFYGGLIRAKNVLSMLTQVTVTFALVCILWVVYGYSLAFGEGNHFFGNADG
                     AMLKNIALTAVTGTIYQYIHVAFQGSFACITVGLIVGALAERIRFSAVLIFVVVWFTL
                     SYIPIAHMVWGGGLLAAHGALDFAGGTVVHINAAIAGLVGAYLIGKRVGFGKEAFKPH
                     NLPMVFTGTAILYIGWFGFNAGSAGSANEIAALAFVNTVVATAAAILGWIIGEWTLRG
                     KPSLLGACSGAIAGLVGVTPACGYVGVGGALVIGVIAGLAGLWGVTMLKRLLRVDDPC
                     DVFGVHGVCGIVGCILTGVFAASSLGGVGFVDGVTMGHQVMVQLESIAITVVWSGVVA
                     FVGYKLADILVGLRVPEEQEREGLDVNSHGENAYNA"
     gene            complement(5451..5789)
                     /gene="glnK"
                     /locus_tag="OPV72_003426"
     CDS             complement(5451..5789)
                     /gene="glnK"
                     /locus_tag="OPV72_003426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HCR9915633.1"
                     /translation="MKLVTVIIKPFKLEDVREALSSIGIQGLTVTEVKGFGRQKGHAE
                     LYRGAEYSVNFLPKVKIDVAIADDQLEEVIDIISKAAYTGKIGDGKIFVAELMRVIRI
                     RTGEADEAAL"
     gene            complement(6002..7783)
                     /locus_tag="OPV72_003427"
     CDS             complement(6002..7783)
                     /locus_tag="OPV72_003427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SmdB family multidrug efflux ABC transporter
                     permease/ATP-binding protein"
                     /protein_id="HCR9915634.1"
                     /translation="MRSFGQLWPTLKRLLAYGSPWRKPLSVAVMMLWIAVAAEVSGPL
                     LISYFIDNMVARHHLPLGKVAGLAAAYVGLQFLAAGLHYAQSLLFNRAAVGVVQSLRT
                     DVMDAALRQPLSAFDTQPVGQLISRVTNDTEVIRDLYVTVVATVLRSAALIGAMLVAM
                     FSLDWRMALVAVLIFPAVLTVMVIYQRYSTPIVRRVRAYLADINDGFNEIINGMSVIQ
                     QFRQQARFGERMGEASRSHYMARMQTLRLDGFLLRPLLSLFSALILCGLLMLFSFTSA
                     GTIEVGVLYAFISYLSRLNEPLIELTTQQSMLQQAVVAGERVFELMDRPRQRYGSDDR
                     PLQSGAIDIDHLSFAYRDDNLVLQDITLSVPSRSFVALVGHTGSGKSTLASLLMGYYP
                     LTQGEIRLDGREIASLNHRVLRQGVAMVQQDPVVMADTFLANVTLGRDVSEAQVWQAL
                     ETVQLADLARGLSDGLHTHLGEQGNTLSVGQKQLLALARVLVDAPQILILDEATASID
                     SGTEQAIQQALAAIRERTTLVVIAHRLSTIVEADTILVLYRGQAVERGTHQQLLAAQG
                     RYWQMYQLQLVGEELAASVHEESGPTA"
     gene            complement(7776..9548)
                     /locus_tag="OPV72_003428"
     CDS             complement(7776..9548)
                     /locus_tag="OPV72_003428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SmdA family multidrug ABC transporter
                     permease/ATP-binding protein"
                     /protein_id="HCR9915635.1"
                     /translation="MRLFAQLSWYFRREWRRYLGAVALLMLIAMLQLIPPKVVGIVVD
                     GVTAQHFTPGRIAMWIGTIALIAVVVYLLRYVWRVLLFGASYQLAVELREDYYRQLSR
                     QHPEFYQRHRTGDLIARATNDVDRVVFAAGEGVLTLVDSLVMGCAVLIVMSTQISWQL
                     TLLALLPMPIMALMIKRYGDRLHDYFKLAQAAFSSLNDRTQESLTSIRMIKAFGLEDR
                     QSSLFAADAEDTGKKNMRVARIDARFDPTIYIAIGMANLLAISGGSWMVVNGSLTLGE
                     LTSFMMYLGLMIWPMLALAWMFNIVERGSAAYSRIRAMLAEAPVVKDGEEPVPAGRGE
                     LTAAIREFCYPQTTHPALENVNFRLKPGQMLGICGPTGAGKSTILSLIQRHFDVTQGE
                     IRFHDMPLTHLQLDSWRSRLAVVSQTPFLFSDSIANNIALGRPEATQEEIERVARLAS
                     VHEDILRLPQGYDTQVGERGVMLSGGQKQRISIARALLLNAEILLLDDALSAVDGRTE
                     HQILHNLRQWGEGRTVIISAHRLSALTDANEIIVMQHGHVVQRGDHDQLAQQIGWYRD
                     MYRYQQLEAALDDAPERGEEAVNA"
     gene            complement(9589..10047)
                     /gene="decR"
                     /locus_tag="OPV72_003429"
     CDS             complement(9589..10047)
                     /gene="decR"
                     /locus_tag="OPV72_003429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator DecR"
                     /protein_id="HCR9915636.1"
                     /translation="MLDKIDRKLLCLLQQDCTLSLQALADAVNLTTTPCWKRLKRLED
                     DGILLGRVALLDPEKLGLGLTAFVLIKTQHHSSEWYCRFVTVVSEMPEVLGFWRMAGE
                     YDYLMRVQVADMKRYDDFYKRLVNSVPGLSDVTSSFAMEQIKYTTSLPIE"
     gene            10160..11215
                     /locus_tag="OPV72_003430"
     CDS             10160..11215
                     /locus_tag="OPV72_003430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent cysteine synthase family protein"
                     /protein_id="HCR9915637.1"
                     /translation="MMSSNWVKNAINEINADHQRSADTHLIRLPLSAFPGIQLYLKDE
                     STHPTGSLKHRLARSLFLYGLCNGWIKEDTPIIEASSGSTAISEAWFARLLGLPFIAA
                     MPACTAKRKIEQIQFYGGHCHFVESACEIYAASERLAHELNGHYMDQFTYAERATDWR
                     GNNNIADSIFRQMRNEPHPVPRFIVMSAGTGGTSATIGRYIRCQGYDTQLMVVDPENS
                     VFLPYWQDRDASLRSPVGSKIEGIGRPRVEPSFIPDVVDEMLRVPDAASVATAHWLET
                     QLGRKVGASTGTNMWGALQLAARMREAGETGAIVTLLCDSGDRYLDTYYHPAWVSDHI
                     GDLTPWSAAIAKLLTGD"
BASE COUNT         2692 a         3259 c         2837 g         2431 t
ORIGIN      
        1 cgctatcaac gctccttttt caaccggtaa acattcacga tctcttcctg gcggcaaaag
       61 caacgtggcg taacgcgtta gtctggcccc tgtatctgta aaatcgataa aatagcttta
      121 tcattcgagg gcgcgattta cgatcggata tactttctct acgctgtgtt tataaggaca
      181 tcactgtgac aacacgacat ctggtcagcc tggtaacggg agtgcttatc ctgtctgtcc
      241 ttttcccgat aggattgagc ctgtggctgg cgcaccgtca agttgaaaaa aggtttaacg
      301 aagagctgga tatcttctcg tcccgggtgg cgctacgtac agaaagggtc agtgaccagg
      361 caaaagccgc gttaacgcat attgcctcct ttaaaggcga gccctgcagc agcgcccatt
      421 tactcgccat gcgccgcgtg tcttatagct ttcggtatgt ccaggaagtt ctgtatctta
      481 aaaattcgat tcccgtttgc tcctcacttg aaaaagagag ccatattccc gctttccctc
      541 cgcccatgaa aatcactcgc gacggttatc gcgcctggtt tacggcgcaa aacgatctgg
      601 gtataaaacg ctatatggcg gcactcggga gcgacagcta tatcgtgatg atcgacccgg
      661 cgtcctttat cgatgtgatt ccgtttggcg catggccgat tgacgtcgct attattggcc
      721 gggaacgcaa tactgtggtt gccagcagcg gtaaccttga ccacgctatt cttccgctca
      781 ttcaccatga gacgcccctg cggctggaaa accgaggcat tcagtatgct atccacccct
      841 ttccggaaat gggcattact atcgtaagct gggcaccgac cgctccgctg gaaaggagct
      901 ggtatcgaca agcgtttatc tggctaccgg cgggcatcgt aacgggtctg ctggctgcgg
      961 cctttattct gcgtattttg cgtcggctac aatcgccccg ccaccgtctc caggatgcga
     1021 tagacaatcg cgaaattaac gtacactatc agcctattgt ctccctgagc agcggaaaaa
     1081 ttgtcggtgc cgaagcctta gctcgctggc aacaggcgga cggcactttc ctttcgccgg
     1141 aaatttttat cgcgctggct gaacaaaccg ggctcacgga gccgctaacc cggctaatca
     1201 tcgacaccgt ttttgaagac atggggagtt ggttaaagtc ccatcccgaa caacatattt
     1261 caatcaatct tgaggcatcc gatctggcgt cggaaacgct cccgacgctg ttaagcacgc
     1321 tgctgaaccg tagccaaatt tctccgtcgc aaatcgcgct tgagttaacg gagcgcgagt
     1381 tcgccgatcc gaaaaccagc gcgcccattg tcgccagata ccgtaacgcg ggacattcca
     1441 tttatattga tgactttggc accggctatt ccagcctcag ctacttacaa aatctggatg
     1501 tggatgtcct taaaattgat aaatcttttg tcgatgcgct ggaatataaa aacgtcacgc
     1561 cgcatattat tgaaatggcg aaaacgctca aacttaagat ggtcgcagaa ggcatcgaaa
     1621 cgaccaggca agaacagtgg ctacgccagc atggcgtaca ttatggtcag ggctggttat
     1681 acagtaagcc cctacccgct acggcattta ttctttgggt ggaacagcgg ctataacgtc
     1741 gcacagcaga aaagaacagt gtggaaaggc agaattgggt gggggccctg ccagctacat
     1801 cccggcacac gcgtcatctg ccttggctgc ttccttccgg acctgacctg gtaaacagag
     1861 tagcgttgcg ggagaaccaa cagagccccc attgagagcg ttgtgaacca acgcgcaggc
     1921 gcattatcac tgctatatcg tgcaattgca acctatcagg catcggatgc tggtttcttg
     1981 cgcatccggg ctttcctccc cccttattcc agattatcct gaagcattaa cgcaggattc
     2041 tattatggat attcaggaca catttcctca acgcgtctgg caaatcgtcg cctcgatccc
     2101 ggaagggttt gtcacgacct acggtgatgt cgcccggctt gccggttccc ctcgggcggc
     2161 gcgtcaggtc ggcggagttt taaaacgtct gccggaaggc agcactttac catggcatcg
     2221 ggtggtgaac cgccacggcg caatatcact taccgggccg gatctacagc ggcaacgtca
     2281 ggcattactg gcggaaggcg tggtggtgtc gggaagcgga caaatcgatt tacaacgcta
     2341 tcgctgggtg tattaaccct ctccgtaacg gagagggttg gcgcaggatt aatactgggt
     2401 aggcgcagga acggcagaag acggattgac ctgggtcggc gaagtcgatg gaaccgtcgt
     2461 cgtcgcaccg ccgctggcct gcacaggcac cgccgtttgc tgtaccggta ccagcgtcag
     2521 atccgcttta gtgccgccat tgttaatcac cggtttcacg ctatcggtaa taaataccag
     2581 cttattgtca acggtgatgg ccgcgctcag aagaatacgc gcgttaggtt gaatatctga
     2641 tgggttaaac ggcaacacaa aactgaaagg cgcctgttta ccttcggtac gtaccgcttt
     2701 ttgcgacagc accttagacg gcgcatcagc cagcgaagca tctgaaagcg tcacggtcag
     2761 caccgcatct ggcggcagag cgaccttctg gcggatccag acggtaccgg aaacattggg
     2821 ttgctgaata gtagactggt tagctgtaat cgacatgtta gggtttggcg caggcgtctg
     2881 gatatcagcg cttttatcag cgcaggccgc cagagatatc gcaaccgcta aaccacttac
     2941 gatgtgcacg agtttcattc aattctcctt atcatcaatg caccagcagg cctttccccc
     3001 cgccggaaga gtggttaaca gaaatacaac gtgattaagt gtggcacatg tcactcattt
     3061 ttgcctggaa ttggtctgtt attcagactt ttgtacccat cggaccactt gcaaaattgc
     3121 gttatactct gccctacctc gcttcggcat cgttgtcacc tggagagtat gtatgagtca
     3181 gacactgaat aatttgctga cattattgaa tctggaaaaa attgaagaag gactctttcg
     3241 gggccaaagt gaagacttag ggctgcgcca ggtatttggc ggtcaggtgg tgggccaggc
     3301 gctctatgcc gccaaagaaa cggtgccgga agcgcgactg gtgcattcat tccacagtta
     3361 ttttctgcgg ccaggcgaca gccaaaaacc cattatctat gacgtagaag tgctgcgcga
     3421 tgggaatagc ttcagcgccc gccgcgttgc cgctattcag aacgggaaac ccatctttta
     3481 catgaccgcc tcattccagg caccggaacc gggttttgaa catcaaaaaa ccatgccgac
     3541 ggcagtcggg ccggaaggac taccgtcaga aacggaaatc gcgcaatcgc tggcgcattt
     3601 actgccgccg attctgaaag aaaagtttct ctgcgatcgc ccgctggaaa ttcgtcccgt
     3661 cgaatttcac aatccgttga aaggtcacgt ctccgcgcct gtgcgtcagg tatggattcg
     3721 cgccaacggc accgttccgg atgacattcg cgtccatcaa tatttactgg gatacgcctc
     3781 ggatctgaat ttccttcccg tcgcgcttca gcctcacggc atcggttttc tggaaaaggg
     3841 cattcagatc gccactatcg atcactctat gtggttccat cgtccgttca attttaatga
     3901 atggctactt tatagcgtgg agagcacttc cgcctccagc gcccggggct ttgttcgcgg
     3961 cgagttttat actcaggatg gcgcgctggt cgcttcaacc gtgcaggaag gggtaatgcg
     4021 taatcacaat taaaaaacat gccgctatgc ggcgttaatg gcctgatgac gctgcgctta
     4081 tccggcctac ggtagactgg gtaagcgcag cgccatcagg catgttgcgc aatcacgcgt
     4141 tatacgcatt ctcgccgtga ctgttcacat ccagcccctc gcgctcctgc tcttccggta
     4201 cacgcagtcc aacaaggata tccgccagtt tgtaaccaac aaacgcgaca acgccggacc
     4261 agacgaccgt aatagcaata ctttccagct gtaccatcac ctgatgtccc atcgtaacgc
     4321 cgtcgacaaa gccgacgcca cccagcgaac tggcggcaaa aacgccggtc aggatacagc
     4381 cgactattcc gcaaacgccg tgaacgccaa atacgtcgca cggatcatct acccgtagca
     4441 gacgtttaag catggtgact ccccacaatc ccgccagacc cgcaataacg ccgataacca
     4501 gcgcgccgcc aacgccaaca tagccacagg ctggcgtcac gccgaccaga ccggcaatcg
     4561 cgccggaaca cgctcccagc agggaaggct taccgcgtag cgtccactcg ccgataatcc
     4621 accccagaat cgcggcggcg gtcgccacca cggtgttcac aaaggccagc gctgctatct
     4681 cgtttgcgct acccgcagaa cccgcgttaa atccaaacca gccgatatac agaatcgcag
     4741 taccggtaaa gaccatcggc aggttatggg gtttaaatgc ttctttccca aagccgacgc
     4801 gtttgccaat taaataagcc cccaccagcc cggcgatagc ggcgttaata tgcaccaccg
     4861 taccaccggc aaaatccagc gcgccgtgag cagccagcag gccgccgccc cacaccatgt
     4921 gcgcaatcgg gatataagag agcgtgaacc acaccacgac aaaaatcagt accgccgaaa
     4981 aacgaatacg ctccgccagc gcgccgacaa tcagcccgac ggtaatacag gcgaaagatc
     5041 cctgaaacgc gacatgaata tactgataaa tcgtacccgt taccgccgtc aacgcgatat
     5101 tcttcaacat cgccccatcg gcattaccga agaaatgatt cccttcgcca aaagccagcg
     5161 aatagccgta caccacccat aaaatacaga ccagcgcaaa ggtgacggtc acttgcgtta
     5221 acattgacag cacattcttg gcgcgaatta atccgccgta aaacagcgcg atacccggta
     5281 tcgtcatgaa cagcaccagc gcggtgcaaa tcatcataaa agcactatcc gctttatcgg
     5341 caaccgctgg cgcggctatc gttagcccag gcagcagcgc cagtgaagcc agtgtggttt
     5401 ttatcatcgc tatcttcatt ttttcatttc ctgttgctgt gtggcgggtc ttacagcgct
     5461 gcttcgtcag cttcgccggt acgaatccga ataacgcgca tgagctccgc gacgaaaatt
     5521 ttgccgtcgc caatttttcc ggtgtaagcc gctttactga tgatatcgat cacctcttcc
     5581 agttggtcgt cggcgatagc cacatcaatt ttgaccttcg gcaggaaatt cacgctgtac
     5641 tccgcgccgc gatacagttc ggcgtgtcct ttctgacggc caaacccttt cacttcggtg
     5701 acggtcagtc cctgaatgcc aatggaagaa agcgcctccc gcacgtcctc cagcttgaac
     5761 ggtttgataa tcacggtaac cagcttcata gaaccctcca gtcagaatta ggtaacggct
     5821 gccgccgcgc atggactctt caggatggat attgcaaagg atgtgccaga agctggcgag
     5881 cgaggaaaag cgcggttagc ggcgcgtctt tatattgacg cgccccaaaa acgaagcagg
     5941 gaaagaaaaa cgcaccacga cggtgcataa tgggcgaggt tttgccctgt ggcgccaaac
     6001 cttacgccgt agggccggat tcttcgtgta cgctggcggc taactcctcg ccaactaact
     6061 gtaattgata catttgccag tagcgccctt gcgccgccag caattgttga tgcgtcccgc
     6121 gctccaccgc ctggccgcga tagagaacca gaatggtatc cgcctccacg attgtcgata
     6181 gccgatgggc aataaccacc aacgtggtgc gctcgcgaat cgccgccagc gcctgctgta
     6241 tcgcctgctc agtgccggaa tcgatgctgg ccgtcgcttc atcaagaatt aatatttgcg
     6301 gggcgtcaac cagcacgcgc gccagcgcca atagctgttt ttgcccgacg gacagcgtat
     6361 ttccctgctc gccgagatgc gtatgcagcc cgtcgctcag gccgcgcgcc agatctgcca
     6421 gttgtaccgt ttccagcgcc tgccacacct gcgcctcgga gacatcgcgc cccagcgtca
     6481 cattagccag aaaggtatcc gccatcacta ccgggtcctg ttgaaccatc gccacgccct
     6541 ggcgtaaaac gcgatgatta agagaggcga tttctcgccc atccagccga atttcgcctt
     6601 gtgtcagggg gtaatacccc attaataagc tggcgagcgt gctcttcccg ctgccggtgt
     6661 gccccaccag cgccacaaag ctacgggacg gtactgatag cgtaatgtcc tgtaaaacaa
     6721 gattatcgtc gcggtaagca aacgacagat gatcaatatc aatcgccccg ctttgtaacg
     6781 gcctgtcgtc gctgccatag cgctggcgcg ggcgatccat cagttcaaaa acacgctctc
     6841 ccgccacaac cgcctgctgt agcatggatt gctgggtggt cagttcaatg agcggctcgt
     6901 tcagacgtga caaatagcta atgaacgcat acagcacccc gacctcaatc gtgccggcag
     6961 acgtaaagct gaaaagcatc aacaaaccgc ataaaatgag cgcggaaaag aggctaagca
     7021 gcggacgcaa taaaaagccg tccaagcgca gcgtctgcat ccgcgccatg tagtgcgagc
     7081 ggctggcctc gcccatgcgt tcgccgaagc gcgcctgctg gcgaaactgc tgaattacgc
     7141 tcatcccatt gatgatttcg ttaaagccgt cgttaatatc cgccaggtat gcccgcacgc
     7201 ggcgtacaat cggcgtgctg tagcgctgat aaatgaccat cacggtcaat accgccggaa
     7261 aaatcaaaac cgccaccagc gccatccgcc agtcaaggct gaacatggcg accagcatgg
     7321 cgccgatcaa cgccgcgcta cgtaataccg ttgcgacgac cgtgacgtac agatcgcgga
     7381 tgacttccgt atcgttggtc acgcgtgaaa ttaattgtcc gacaggctgc gtgtcgaagg
     7441 cgcttagcgg ctggcgcaag gcggcatcca tgacgtccgt gcgcaaggac tgaaccacgc
     7501 caacggccgc ccggttaaat aataaagact gggcgtaatg cagacccgcc gccagaaact
     7561 gtagccccac ataggcggcc gccagccccg cgaccttgcc caacggtaaa tggtggcggg
     7621 ccaccatgtt atcaatgaaa tagctgatca gcagcggacc gctaacctcc gccgccaccg
     7681 caatccacag catcatcacc gcgacagaga gcggttttcg ccatggcgag ccatacgcca
     7741 gcaaccgttt cagcgtcggc catagctgtc caaaactacg cattcaccgc ctcctcgccg
     7801 cgttccggcg cgtcatccag agcggcctcc agttgctgat agcgatacat atcgcgatac
     7861 cagccaatct gctgcgccag ttgatcgtga tcgccgcgct gaacaacatg accatgttgc
     7921 ataacgataa tttcattggc gtcggtcagc gcggataaac gatgcgcgct gatgatgacc
     7981 gtacgccctt cgccccactg gcgcaaatta tgcaaaatct gatgctccgt acgaccatct
     8041 actgctgaaa gcgcatcatc aagaagcaga atttccgcat tcaacagtag cgctctggct
     8101 atcgagatac gctgtttttg cccacccgat aacatgacgc cacgttcacc tacctgcgtg
     8161 tcatagccct gaggcaaacg gagaatatcc tcatgtacgc tggctaaacg cgccacccgt
     8221 tcaatctctt cctgggtcgc ctccgggcgt ccgagcgcaa tattattggc aatagaatcc
     8281 gagaacaaaa acggcgtctg gctgacgacc gccagtcggc tacgccagct atccagttgc
     8341 agatgcgtca acggcatgtc atggaatcgg atctctccct gcgtcacatc aaaatggcgc
     8401 tggataagcg acaagattgt gcttttcccc gcgccggtcg gaccgcatat ccccagcatc
     8461 tgacccggtt taagacgaaa gttcacattc tccagcgccg gatgcgtcgt ttgcggatag
     8521 caaaactcac gaatggccgc cgtcagttcg ccccgccccg ccgggacggg ctcttcgcca
     8581 tccttaacta ccggcgcttc cgccagcatg gcgcggatgc ggctgtaagc ggcgctaccc
     8641 cgctccacga tattaaacat ccaggccagc gccagcatcg gccaaatcat caaccccaga
     8701 tacatcataa agctggtgag ttcgcccagc gtcaggctgc cgttaaccac catccagctt
     8761 ccgccgctaa tcgcgagcag gttcgccatg ccaatggcga tgtaaatggt tggatcaaaa
     8821 cgcgcgtcaa tacgcgccac gcgcatattt ttcttgccgg tatcttcggc atccgccgca
     8881 aacagcgaag actggcggtc ctccagacca aacgctttga tcatgcggat gctggtcaga
     8941 ctctcctgcg tgcggtcgtt caggctggag aaggcggcct gcgccagttt gaaataatca
     9001 tgcagtcgat cgccgtaacg tttgatcatc agcgccataa tcggcatcgg caacagcgct
     9061 aatagcgtta gctgccagct aatttgcgtc gacatgacaa tcagtaccgc gcagcccatt
     9121 accagcgagt caaccagcgt cagaacgccc tcgcccgccg caaatacgac gcgatccaca
     9181 tcattcgtcg cacgcgcaat aagatcgccc gttcgatggc gctgataaaa ttcaggatgc
     9241 tgacgactca gctggcgata ataatcttca cgcagttcga cggctaattg ataagaagcg
     9301 ccaaatagca gcacgcgcca gacatagcgc aacaaataga ccactacggc gatcagggca
     9361 atggtgccaa tccacatcgc tattcggcct ggagtaaaat gctgtgcggt tacgccatcc
     9421 acgacaatcc ccaccacttt gggcgggatc agctgaagca tcgcaataag cataagcagg
     9481 gccaccgcgc caagatagcg acgccattcc cggcgaaagt accagcttaa ttgagcaaat
     9541 aatcgcacgc gttatttcct gatatgattt ccggcaatac cgggagaatt attcaatggg
     9601 cagagaggtg gtgtacttaa tctgttccat cgcaaaactg gaggtgacgt ctgacagtcc
     9661 tgggacgcta ttgaccagac gtttatagaa gtcgtcatac cgcttcatgt cggccacctg
     9721 aactcgcatc agatagtcgt actcccccgc catccgccag aagccaagca cttccggcat
     9781 ctcagagacg acggtcacga accgacagta ccattcactg ctgtggtgct gcgtttttat
     9841 caacacaaaa gcggttaacc ccagccccag tttttccggg tccagcagcg caaccctgcc
     9901 aagcaggata ccgtcatctt ccaggcgttt aagccgcttc cagcaaggcg ttgtcgtcag
     9961 attaacggca tccgccagcg cctgcaaaga gagggtacag tcctgctgca ataagcaaag
    10021 cagtttacgg tcaattttat ctaacatacc cactccatag agaatatttt tctccttaca
    10081 ttgtaattta aaggtcaaat agcaacaatt ttttccgtac ttttcgctac tcttggcaca
    10141 aaatgataaa tggatattaa tgatgagtag caattgggtt aaaaatgcca ttaatgaaat
    10201 taacgctgac caccagcgct cagcggatac gcatcttatt cgtttgcccc tgtcggcatt
    10261 tccaggtatc cagctttacc tgaaagacga aagcacgcat cccaccggta gcctcaagca
    10321 tcgtctggcg cgctcgctgt tcctttatgg gttgtgcaat ggctggatta aagaagacac
    10381 tccgattatt gaagcgtcat caggctcaac ggcgatttcc gaagcctggt tcgcgcgttt
    10441 actgggactg ccgttcatcg ccgccatgcc cgcctgtacc gcaaaacgta aaatcgaaca
    10501 gattcaattt tacggcggcc actgtcattt tgtggagagc gcctgcgaaa tttatgccgc
    10561 ctccgagcgg ctggcgcatg aactgaacgg tcactatatg gaccagttta cctacgcaga
    10621 acgagctacc gactggcggg gcaacaataa tattgccgac agtattttcc gccagatgcg
    10681 caacgaaccc catccggtac cgcgatttat cgtcatgagc gccggaacgg gcggaacctc
    10741 tgcgacgatt gggcgctata ttcgctgcca gggctatgat actcagctca tggtggtgga
    10801 tccggaaaat tctgtctttt taccttactg gcaggatcgc gacgcttcat tacgcagccc
    10861 ggtaggcagt aaaattgaag gaattggtcg tccgcgagta gagccttctt ttattccgga
    10921 tgtcgtggat gagatgctgc gcgtgccgga cgccgccagc gttgccaccg cacactggct
    10981 ggaaacgcag ctaggccgta aagtcggcgc ctctaccggc acgaatatgt ggggagcgct
    11041 gcagctagcg gcccggatgc gcgaggctgg agaaaccggc gctatcgtga cgttattgtg
    11101 cgatagcggc gatcgctatc tggataccta ttaccatccg gcctgggtta gcgaccatat
    11161 cggcgatttg acgccgtggt cagcggccat cgcaaaatta cttaccggcg actagaaac
//
LOCUS       DAJVBX010000159        11199 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.159, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000159 DAJVBX010000000
VERSION     DAJVBX010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 11199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11199
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.159"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(46..3492)
                     /gene="mfd"
                     /locus_tag="OPV72_003431"
     CDS             complement(46..3492)
                     /gene="mfd"
                     /locus_tag="OPV72_003431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HCR9915638.1"
                     /translation="MPEKQRYTLPTKAGDQRQLGELTGAACATLVAEIAERHAGPVVL
                     IAPDMQNALRLHDEIRQFTDQMVMNLADWETLPYDSFSPHQEIISSRLSTLYQLPSMQ
                     RGVLIVPVNTLMQRVCQHSYLHGHALVMKKGQRLSRDALRAQLDSAGYRHVDQVMEHG
                     EYATRGALLDLFPMGSEQPYRLDFFDDEIDSLRLFDADTQRTLEEVEAINLLPAHEFP
                     TDKAAIELFRSQWRDTFEVKRDAEHIYQQVSKGTLPAGIEYWQPLFFSEPLPPLFSYF
                     PANTLVVNTGSLETSAERFQADTLARFENRGVDPMRPLLPPEALWLRVDGLFSELKRW
                     PRLQLKTDHLPEKAANTNLGFQKLPDLAIQAQQKAPLDALRKFLESFSGPVIFSVESE
                     GRREALGELLARIKIAPKRILRLDEAQDAGRYLMIGAAEHGFIDTQRNLALICESDLL
                     GERVARRRLDSRRTINPDTLIRNLAELHVGQPVVHLEHGVGRYAGMTTLEAGGIKGEY
                     LMLTYANDAKLYVPVSSLHLISRYAGGAEESAPLHKLGGDAWSRARQKAAEKVRDVAA
                     ELLDIYAQRAAKEGFAFKHDREQYQLFCDSFPFETTPDQAQAINAVLSDMCQPLAMDR
                     LVCGDVGFGKTEVAMRAAFLAVENHKQVAVLVPTTLLAQQHYDNFRDRFANWPVRIEM
                     LSRFRSAKEQTQILAEAAEGKIDILIGTHKLLQSDVKLRDLGLLIVDEEHRFGVRHKE
                     RIKAMRADVDILTLTATPIPRTLNMAMSGMRDLSIIATPPARRLAVKTFVREYDSLVV
                     REAILREILRGGQVYYLYNDVENIQKAAERLAELVPEARIAIGHGQMRERELERVMND
                     FHHQRFNVLVCTTIIETGIDIPTANTIIIERADHFGLAQLHQLRGRVGRSHHQAYAWL
                     LTPHPKAMTADAQKRLEAIASLEDLGAGFALATHDLEIRGAGELLGEEQSGSMETIGF
                     SLYMELLENAVDALKAGREPSLEDLTSQQTEVELRMPSLLPDDFIPDVNTRLSFYKRI
                     ASAKNENELEEIKVELIDRFGLLPDPARNLLDIARLRQQAQKLGIRKLEGNEKGGTIE
                     FAEKNHVDPAWLIGLLQKQPQHFRLDGPTRLKFIQDLSERKTRIDWVRQFMQQLEENA
                     IA"
     gene            3830..5029
                     /gene="lolC"
                     /locus_tag="OPV72_003432"
     CDS             3830..5029
                     /gene="lolC"
                     /locus_tag="OPV72_003432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004976588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein-releasing ABC transporter permease
                     subunit LolC"
                     /protein_id="HCR9915639.1"
                     /translation="MYQPVALFIGLRYMRGRAADRFGRFVSWLSTIGITLGVMALVTV
                     LSVMNGFERELQNNILGLMPQAILSAEHGSLNPNQMPEKAVNLQGVNRIAPLTTGDVV
                     LQSARSVAVGVMLGIDPAQKDPLTPYLVNVKQSELQPGKYNVILGEQLAGQLGVNRGD
                     QIRLMVPSASQFTPMGRLPSQRLFTVIGTFAANSEVDGYEMLVNIQDASRLMRYPAGN
                     ITGWRLWLDEPLQVDTLSQQTLPQGTKWQDWRERKGELFQAVRMEKNMMGLLLSLIVA
                     VAAFNIITSLGLMVMEKQGEVAILQTQGLTPRQIMMVFMVQGASAGIIGALLGAALGA
                     LLASQLNNLMPIIGAFLDGAALPVAIEPLQVIVIALVAMAIALLSTLYPSWRAAATQP
                     AEALRYE"
     gene            5022..5723
                     /gene="lolD"
                     /locus_tag="OPV72_003433"
     CDS             5022..5723
                     /gene="lolD"
                     /locus_tag="OPV72_003433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein-releasing ABC transporter
                     ATP-binding protein LolD"
                     /protein_id="HCR9915640.1"
                     /translation="MNKILLQCDNLCKRYQEGTVQTDVLHDVSFSIGEGEMMAIVGSS
                     GSGKSTLLHLLGGLDTPTSGDVIFSGQPMSKLSSAAKAELRNQKLGFIYQFHHLLPDF
                     TALENVAMPLLIGKKKPAEIDARAREMLHAVGLEHRATHRPSELSGGERQRVAIARAL
                     VNNPRLVLADEPTGNLDARNADSIFELLGELNRLQGTAFLVVTHDLQLAKRMSRQLEM
                     RDGRLTAELSLMGAE"
     gene            5723..6967
                     /gene="lolE"
                     /locus_tag="OPV72_003434"
     CDS             5723..6967
                     /gene="lolE"
                     /locus_tag="OPV72_003434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein-releasing ABC transporter permease
                     subunit LolE"
                     /protein_id="HCR9915641.1"
                     /translation="MASPLSLLIGLRFSRGRRRGGMVSLISVISTIGIALGVAVLIVG
                     LSAMNGFERELNNRILAVVPHGEIEAVNQPWTNWREALAKVQKVPGIAAAAPYINFTG
                     LVESGANLRAIQVKGVDPKQEQQLSALPSFVQNHAWDHFKAGEQQIIIGKGVADALNV
                     KQGDWVSIMIPNANADHKLLQPKRVRLHVIGILQLSGQLDHSFAMIPLEDAQQYLDMG
                     SSVSGIALKVHDVFNANKLVRDAGEVTNSYVYIKSWIGTYGYMYRDIQMIRAIMYLAM
                     ILVIGVACFNIVSTLVMAVKDKSGDIAVLRTLGAKDGLIRAIFVWYGLLAGLLGSLIG
                     VAIGVVVSLQLTAIINGIEKEIGHQFLSGDIYFIDFLPSELHWLDVVYVLVTALLLSL
                     LASWYPARRASNIDPARVLSGQ"
     gene            6996..7904
                     /gene="nagK"
                     /locus_tag="OPV72_003435"
     CDS             6996..7904
                     /gene="nagK"
                     /locus_tag="OPV72_003435"
                     /EC_number="2.7.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine kinase"
                     /protein_id="HCR9915642.1"
                     /translation="MYYGFDIGGTKIALGVFDSTRRLQWEKRVPTPHTSYSAFLDAVC
                     ELVAEADQRFGVKGSVGIGIPGMPETEDGTLYAANVPAASGKPLRADLSARLDRDVRL
                     DNDANCFALSEAWDDEFTQYPLVMGLILGTGGGGLVLNGKPITGQSYITGEFGHMRLP
                     VDALTLMGFDFPLRRCGCGQMGCIENYLSGRGFAWLYQHYYDQSLQAPEIIALWEQGD
                     EQAHAHVERYLDLLAVCLGNILTIVDPDLLVIGGGLSNFTAITTQLAERLPRHLLPVA
                     RAPRIERARHGDAGGMRGAAFLHLTD"
     gene            7923..8744
                     /gene="cobB"
                     /locus_tag="OPV72_003436"
     CDS             7923..8744
                     /gene="cobB"
                     /locus_tag="OPV72_003436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HCR9915643.1"
                     /translation="MQSRRFHRLSRFRKNKRLLRERLRQRIFFRDRVVPEMMENPRVL
                     VLTGAGISAESGIRTFRAADGLWEEHRVEDVATPEGFARNPGLVQTFYNARRQQLQQP
                     EIQPNAAHLALAKLEEALGDRFLLVTQNIDNLHERAGNRNIIHMHGELLKVRCSQSGQ
                     ILEWNGDVMPEDKCHCCQFPAPLRPHVVWFGEMPLGMDEIYMALSMADIFIAIGTSGH
                     VYPAAGFVHEAKLHGAHTVELNLEPSQVGSEFEEKHYGPASQVVPEFVDKFLKGL"
     gene            complement(8826..9872)
                     /gene="potD"
                     /locus_tag="OPV72_003437"
     CDS             complement(8826..9872)
                     /gene="potD"
                     /locus_tag="OPV72_003437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein PotD"
                     /protein_id="HCR9915644.1"
                     /translation="MKKWSRHLLAAGALALGMSAAHASDNDTLYFYNWTEYVPPGLLE
                     QFTKETGIKVIYSTYESNETMYAKLKTYKDGAYDLVVPSTYYVDKMRKEGMIQKIDKS
                     KLTNFHNLDPEMLNKPFDPNNDYSVPYIWGATAIGVNSDAIDPKTITSWADLWKPEYK
                     NSLLLTDDAREVFQMALRKLGYSGNTTDPKEIEAAYEELKKLMPNVAAFNSDNPANPY
                     MEGEVNLGMVWNGSAFVARQAGTPLEVVWPKEGGIFWMDSLAIPANAKNKEGALKLIN
                     FLLRPDVAKEVAETIGYPTPNLAARKLLSPEVANDKSLYPDAQTISKGEWQNDVGDAS
                     AIYEEYYQKLKAGR"
     gene            complement(9897..10676)
                     /gene="potC"
                     /locus_tag="OPV72_003438"
     CDS             complement(9897..10676)
                     /gene="potC"
                     /locus_tag="OPV72_003438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter permease
                     PotC"
                     /protein_id="HCR9915645.1"
                     /translation="MIGRLLRGGFMTAIYAYLYIPIIILIVNSFNSSRFGINWQGFTT
                     KWYELLVNNDSLLQAAQHSLTMAIFSATFATLIGSLTAVALYRYRFRGKPFVSGMLFV
                     VMMSPDIVMAISLLVLFMLLGIQLGFWSLLFSHITFSLPFVVVTVYSRLKGFDVRMLE
                     AAKDLGASEVTILRKIILPLAMPAVAAGWLLSFTLSMDDVVVSSFVTGPGYEILPLKI
                     YSMVKVGVSPEVNALATVLLVLSLVMVIASQLIARDKTKGR"
     gene            complement(10992..>11199)
                     /gene="sifA"
                     /locus_tag="OPV72_003439"
     CDS             complement(10992..>11199)
                     /gene="sifA"
                     /locus_tag="OPV72_003439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460194.1"
                     /note="translocated by the type III secretion system
                     SPI-2; required for the formation of lysosomal
                     glycoprotein structures (Sifs); required for maintenance
                     of membrane in the Salmonella-containing vacuole; a
                     cysteine residue with CAAX motif is modified by isoprenoid
                     addition of protein geranylgeranyl transferase I; also
                     modified by S-acylation; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="SPI-2 type III secretion system effector SifA"
                     /protein_id="HCR9915646.1"
                     /translation="DKTFQAFLVTDPSASLSMLAEIVEAISDQVFHAIFRIAPQSIQK
                     MAEEQLTTLHVRSEQQSGYLCCFL"
BASE COUNT         2461 a         2908 c         3144 g         2686 t
ORIGIN      
        1 gtaaagatta ggccgggcgc agagtaatga cgcccggcct gacgcttatg caatagcgtt
       61 ttcttccagt tgctgcatga actggcgtac ccagtctata cgcgttttac gttcgcttaa
      121 atcctgaata aacttgaggc gcgtcgggcc atccagacgg aaatgctgcg gctgtttttg
      181 cagtaacccg ataagccagg cggggtcaac gtggtttttc tcggcgaact caatcgttcc
      241 acctttctcg ttaccctcca gttttcggat gccgagcttt tgcgcctgtt ggcgcaggcg
      301 ggcgatatcc agcagattac gcgccggatc gggcagcagg ccgaagcggt cgatcaattc
      361 cactttgatc tcttccagct cgttttcgtt cttcgcgctg gcaatgcgtt tatagaatga
      421 cagccgggta ttaacatccg gaataaaatc atccggcagt aacgacggca ttcgcagctc
      481 gacttccgtt tgctgactgg tgagatcttc cagcgagggt tcgcggcctg ctttcagcgc
      541 atcaacggcg ttttccagca attccatgta gagtgagaag ccaatggttt ccattgagcc
      601 gctttgctct tcgccaagca gctcgcccgc gccgcggatc tccagatcgt gggtcgccag
      661 cgcaaacccg gcgcctaaat cctccagcga cgcaatcgcc tccagccgtt tttgcgcatc
      721 ggcggtcatg gccttaggat gtggcgtcaa cagccaggcg taggcctggt ggtgcgagcg
      781 ccctacgcgg ccacgcagct ggtgcaactg cgcgaggccg aaatgatccg cgcgttcaat
      841 gatgatcgtg ttagcggtgg gaatgtcgat ccccgtttcg ataatggtag tacacaccag
      901 cacgttaaaa cgttgatggt ggaaatcgtt catgacccgt tccagctcac gttcgcgcat
      961 ctgcccgtgg cctatagcga ttcgcgcttc cggcaccagt tccgccagcc gctctgcggc
     1021 tttctgaata ttttcgacgt cattgtacaa atagtaaacc tgaccgccgc gcaggatttc
     1081 acgcagaatc gcttccctta ccaccaggct atcatactcg cggacaaagg tttttaccgc
     1141 cagacgacgg gcagggggag tggcgataat ggagagatcg cgcataccgc tcatcgccat
     1201 attcagcgtc cgcgggatcg gcgtcgccgt gagcgtcaga atatcgacat cggcgcgcat
     1261 cgccttaatt cgctctttgt ggcgcacgcc gaaacggtgc tcttcatcga caatcagcag
     1321 gccgaggtcg cgtagcttca catcgctttg tagcagttta tgcgtaccga tcagaatatc
     1381 gatcttacct tcggcggctt ccgccaggat ttgcgtctgc tctttggcgc tgcgaaagcg
     1441 ggacagcatc tcaatgcgta ccggccagtt ggcgaaacgg tcgcggaagt tgtcatagtg
     1501 ttgctgcgcc agcagcgtag tcggcaccag taccgccacc tgtttatggt tttccaccgc
     1561 caggaacgcg gcgcgcatcg ccacttcggt tttgccgaag ccgacgtcgc cgcacaccag
     1621 cctgtccatc gccagcggtt ggcacatatc gctcaatacg gcgttaatcg cctgtgcctg
     1681 atcgggcgtc gtttcaaacg ggaagctgtc gcagaataac tgatactgct cacgatcatg
     1741 cttaaaggca aaaccctctt ttgccgctcg ttgcgcataa atatccaaca gttccgctgc
     1801 gacatcgcgc actttttccg ccgctttctg ccgggcgcgc gaccaggcgt cgccgcccag
     1861 tttatgcagc ggcgcacttt cttccgcgcc gccggcatag cggctaatca gatgcaatga
     1921 ggagaccggc acatacagtt tggcgtcatt ggcgtaagtg agcatcagat attcaccctt
     1981 gatgccgcca gcctccagag tggtcatgcc ggcatagcgt ccgacgccgt gctccagatg
     2041 cactaccggt tgaccgacgt ggagctccgc caggttacga atcaacgtat ccgggttgat
     2101 cgtgcggcgg gaatccaggc ggcgacgcgc cacccgctca cccaaaagat cgctttcaca
     2161 aatcagcgcc agattgcgtt gggtgtcgat aaagccatgt tctgcggcgc caatcatcag
     2221 atagcgtccc gcatcctgcg cctcgtccag gcgtaatatt cgcttcggcg cgatttttat
     2281 gcgagccagg agctctccca gagcttcgcg gcgtccttcg ctttccaccg aaaaaatcac
     2341 cggaccgctg aaagattcga ggaacttacg cagcgcgtcc agcggcgctt tctgctgtgc
     2401 ctggatagcc aaatccggta atttctggaa accgagattg gtattggcgg ctttttccgg
     2461 cagatggtcg gttttaagct ggaggcgagg ccagcgttta agctcggaaa agagcccatc
     2521 cacccgtagc cagagggctt ccggcggcaa aagcgggcgc ataggatcga cgccacgatt
     2581 ttcaaaacgc gccagcgtat cggcctgaaa gcgttcggcg ctggtttcca gcgagccggt
     2641 attcaccacc agagtattgg cggggaaata gctaaataat ggcggtaacg gttcgctgaa
     2701 aaagagcggc tgccagtatt cgatcccggc gggcagagtg cctttgctaa cctgctgata
     2761 gatgtgctcg gcgtcgcgtt ttacctcaaa ggtatcgcgc cactggctac ggaaaagctc
     2821 aatagcggct ttgtcggtag gaaattcgtg cgcgggcaac aaattgatgg cctcaacctc
     2881 ctccagcgta cgctgggtat ccgcgtcaaa cagacgcagg ctgtcaattt catcatcaaa
     2941 aaagtcgagg cgataaggct gttcgctgcc catcggaaag agatccaaca gcgcgccgcg
     3001 cgtcgcgtat tcgccatgct ccatcacctg atcgacatgc cgataaccgg cgctgtcaag
     3061 ctgcgcgcgc agagcgtcgc gggacagccg ctggcctttt ttcatcacca gcgcatgacc
     3121 atgcagatag ctatgctgac aaacgcgctg catcagggtg tttaccggta caatcaagac
     3181 gccgcgctgc attgacggca actggtagag cgtggacagg cgcgaagaga taatttcctg
     3241 atgcggggag aagctgtcat acggtagcgt ttcccagtcc gccaggttca tgaccatctg
     3301 atcggtaaac tggcggattt catcatgcaa tcgcagagca ttttgcatgt caggcgctat
     3361 gagtaccacc ggaccggcat ggcgttcagc tatctccgcc accagcgtag cgcaggcggc
     3421 accggtaagt tcgcccaact ggcgctgatc gcccgctttt gtcggcagcg tgtaacgttg
     3481 tttttcaggc ataacggttg tcagtatctc tttttgtttt acgccgcact ctacgcgtca
     3541 cccttcaggc tgcttcatgg ttggctgcgc gccaggacag catgaaggac tcaggtattc
     3601 aggggcatat gactgataag caatgttctt tattatccgc gatcgttgtt tattagcaaa
     3661 ttgaatccgc cggataacac gccgaacagg taaagtatga acatgtaagt gacttgattt
     3721 gtcggccttt ttcagaataa cgctgacgaa ctcttacggt tcagacattt acgcattccg
     3781 ctttcgctta tatactcggg actttgctaa cagcaaccag acggattaca tgtatcaacc
     3841 tgtcgcttta ttcatcggcc tgcgttacat gcgcgggcgt gcagcagatc gcttcggtcg
     3901 cttcgtttcc tggctttcca ctatcggcat taccctgggg gtgatggcgc tggtcacggt
     3961 attgtcggtg atgaacggtt ttgagcgcga actgcaaaat aacattcttg gtttgatgcc
     4021 tcaggccatc ctctctgctg aacatggttc tcttaacccg aatcagatgc cggaaaaagc
     4081 ggtgaatctg caaggcgtta accgtattgc gccgctgacg acgggcgatg tcgtactgca
     4141 aagcgcgcgt agcgttgcgg ttggcgtgat gttgggtatc gatccggcgc aaaaagatcc
     4201 gttaacgccg tatctggtca atgtgaagca aagcgaatta cagccgggta agtataatgt
     4261 catcctcggc gagcagctcg ccggacagtt aggggtcaac cgcggcgatc agattcggct
     4321 aatggtgcca tctgccagcc agtttacgcc aatgggacgc ctgcccagcc agcgtctgtt
     4381 tacggtgatt ggcacatttg ccgccaatag cgaggtcgat ggctatgaaa tgctggtcaa
     4441 tattcaggac gcgtcgcgtt taatgcgcta tccggcaggc aatattaccg gctggcgtct
     4501 gtggctggat gaaccgctgc aagtcgatac tctcagccaa cagacgctgc cgcaaggcac
     4561 gaagtggcag gactggcgcg aacgtaaagg cgagttgttc caggctgtgc gcatggaaaa
     4621 gaacatgatg ggattgttgc tgagcctcat cgtggcggtc gcggctttta acattattac
     4681 ttcgttgggt ctgatggtca tggagaagca gggcgaagtg gcgattttac aaactcaagg
     4741 gctgacgccg cgacaaatta tgatggtctt tatggtgcag ggcgccagcg ccgggattat
     4801 cggcgcgctg ttgggcgccg cgctgggcgc attgcttgcc agccaactga ataacctgat
     4861 gccgatcatc ggcgcgtttc tggatggcgc tgcgttgccc gtggcgatag agccgttaca
     4921 ggtgatcgtt atcgcgctgg tggcaatggc catcgcgctg ctttctacgc tttatccttc
     4981 ctggcgcgct gccgccactc aacccgctga ggctttacgt tatgaataag atcctgttgc
     5041 aatgcgacaa cctgtgcaaa cgctatcagg aaggcaccgt acaaaccgac gtgttgcacg
     5101 atgtcagctt cagtatcggc gaaggcgaaa tgatggcgat cgtcggcagt tccggttcgg
     5161 gtaaaagtac gttgctgcat ctgttaggcg ggctggatac gcctacctct ggcgatgtga
     5221 tttttagcgg ccagccgatg agcaaactct cttctgcggc aaaagcggaa ttacgtaacc
     5281 agaaactggg gtttatctat cagtttcatc atctcctgcc ggattttacg gcgctggaaa
     5341 acgtggcgat gccattattg attggcaaaa agaaaccggc ggagattgac gctcgggcgc
     5401 gagaaatgtt gcatgctgta gggctggagc atcgcgcaac ccatcgacct tcggaacttt
     5461 ccggcggtga gcgccagcgt gtcgcgatag cgcgcgcgtt ggtgaataac ccgcgtctgg
     5521 tactggcgga tgagccgacc ggtaatctgg atgcgcgtaa tgccgacagt atttttgagc
     5581 ttctgggcga gttaaatcgt ctgcagggaa ccgcgtttct ggtggtgact cacgatttgc
     5641 aactggcgaa acgtatgagc cgccagcttg agatgcgcga tggccgcctg acagcggaac
     5701 tgagcctgat gggggctgag taatggcgtc gcctttatca ttgttaattg gcttgcgttt
     5761 cagccgtgga cggcggcgcg gcggtatggt ttcgctcatt tccgtcattt ctaccatcgg
     5821 tatcgcgctg ggcgtggcgg tgttgattgt cggtttaagc gcgatgaacg gtttcgaacg
     5881 cgagttgaat aaccgtattc tggcggtggt tccacacggg gagattgaag cggtcaatca
     5941 gccgtggacc aactggcgtg aagcgctggc aaaagtgcag aaggtgccgg gcattgccgc
     6001 cgccgcgccg tatatcaatt ttaccggcct ggtagagagc ggggcgaatt tgcgcgccat
     6061 tcaggttaaa ggcgtcgatc ctaagcaaga gcagcagctt agcgcgttac cgtcatttgt
     6121 gcaaaatcac gcctgggatc atttcaaagc gggcgagcag cagatcatta tcggtaaagg
     6181 cgtcgccgat gcgctgaacg tgaaacaggg cgactgggtg tccatcatga tccccaatgc
     6241 gaatgccgac cataagctgc tccagcccaa acgcgtgcgt ttgcatgtca tcgggattct
     6301 gcaactgagc ggccagctcg atcacagctt cgccatgatc ccgcttgagg atgcgcagca
     6361 gtatctggat atggggtcca gcgtttccgg tatcgcgctt aaagtccacg acgtgtttaa
     6421 tgcgaacaaa ctggtgcgtg atgcgggtga agtgactaac agctatgtct acattaagag
     6481 ctggatcggc acctacggct atatgtatcg cgatatccag atgattcgcg ccattatgta
     6541 tctggcgatg attctggtga tcggcgtggc ctgttttaat atcgtttcca ccttagtgat
     6601 ggcggtaaaa gacaaaagcg gcgacattgc ggtattaaga acgctggggg cgaaagatgg
     6661 tttgattcgt gccattttcg tctggtacgg actactggcg ggcttgctgg gcagcttgat
     6721 tggcgtggcg atcggcgttg tcgtttcgct tcagcttacc gccattatta atgggattga
     6781 aaaggagatc gggcatcagt ttttgtccgg cgatatctat tttatcgact tcctgccatc
     6841 cgaattacat tggctggacg ttgtttacgt actggtcacg gcgttgttgt taagcttact
     6901 ggcgagctgg tatccggcgc ggcgggcgag caacattgac cctgcgcgag tattgagcgg
     6961 ccagtaatcg cggaatataa aaacaaggag cggcgatgta ttacgggttt gacattggcg
     7021 gaacaaagat tgcgttaggc gtatttgact caacgcggcg gctgcagtgg gaaaaacggg
     7081 ttcccacgcc ccataccagc tatagcgcct ttttagacgc cgtgtgcgaa ctggtcgcgg
     7141 aagccgacca gcgatttggc gtaaaagggt cggtagggat tggcataccc ggtatgccgg
     7201 aaactgaaga cggcacgctg tacgccgcga atgtcccggc agccagcggt aagccgttgc
     7261 gcgccgatct cagcgcccga ctggatcgcg atgtgcgtct ggacaatgac gctaactgtt
     7321 ttgccttgtc cgaagcctgg gatgatgaat tcacgcaata tcctttggtt atggggctta
     7381 tcctcggcac cggcggcggc ggcctggtgc taaacgggaa gccgattacc ggtcagagct
     7441 atatcaccgg cgagtttggc catatgcgtt tgccggttga cgcgctaacg ttgatggggt
     7501 ttgattttcc tctccgccgt tgtggatgcg gccagatggg ctgcattgag aattatctgt
     7561 ccgggcgcgg gtttgcgtgg ctatatcaac attattatga tcaatcgctg caggcgccgg
     7621 agattatcgc gttgtgggag cagggtgatg agcaggcgca cgcgcatgtt gagcgctatc
     7681 tggatttact ggcggtttgt ctggggaata tactgacgat tgtcgatccc gatttattgg
     7741 tgatcggcgg cggactatcg aactttacgg caataacaac gcaactggcg gaaagactgc
     7801 cgcgccatct cctccctgtt gcccgcgcgc cgcgcattga gcgtgcgcgg catggggatg
     7861 caggtgggat gcgcggtgct gcttttttac atcttaccga ctaatcaaaa aaagaggttg
     7921 ttatgcagtc gcgtcggttt catcgattaa gccgctttcg taaaaataaa cgtctgttgc
     7981 gtgaacgtct gcgccagcgg atctttttca gagacagagt ggtgccggaa atgatggaaa
     8041 acccaagagt attagtcctt acaggtgcag gaatttctgc agagtctggt attcgtacgt
     8101 ttcgcgcggc ggatggcctt tgggaagagc atcgggttga agacgtggca acgccggaag
     8161 gattcgcccg taatccgggg ctggtgcaga cattttataa tgcccgccgt cagcagcttc
     8221 aacagccgga aatacaaccc aatgcggcgc atctggcgtt agcgaagctt gaagaagcgc
     8281 ttggcgatcg ctttttgctg gtgacgcaaa acatcgacaa tttgcatgaa cgcgcgggca
     8341 accgcaacat cattcatatg catggcgagc tgttgaaggt gcgctgttcg caaagcggcc
     8401 agattctgga atggaacggc gatgtgatgc cggaagataa atgtcactgc tgccagttcc
     8461 cggcgccgct acgtccgcac gtggtgtggt ttggcgagat gccgcttggc atggatgaaa
     8521 tttatatggc gctgtcgatg gcggatattt ttatcgccat tggcacatcc ggtcatgtct
     8581 atccggctgc gggttttgtg catgaagcaa aactgcacgg cgcacatacg gtggaactga
     8641 atcttgagcc aagccaggtc ggcagcgagt ttgaagagaa gcactacggc ccggcaagcc
     8701 aggttgtgcc ggaatttgtt gataaattcc tgaaagggct gtagtgccgt ttgcccggta
     8761 acgccttatc cggcctacat ttcacgttac gttcatctgt aggcccgaca ggcgctttgg
     8821 ctgaattagc gtcctgcttt tagcttctga taatactctt cataaatggc gctggcgtcg
     8881 ccgacatcgt tttgccactc gcctttgctg atggtttgcg catccggata gagcgactta
     8941 tcattggcga cctccgggct taacagctta cgcgccgcca ggttgggggt agggtagccg
     9001 atggtttctg ccacctcttt cgcgacgtca ggacgcagca ggaagttgat tagcttcagc
     9061 gcgccctctt tatttttcgc gtttgccgga atagccaggc tatccatcca gaaaataccg
     9121 ccttctttcg gccagacgac ctccagcggc gtgccagcct gacgagcaac gaaggccgaa
     9181 ccgttccaca ccatccccag attgacttcc ccttccatat acggattcgc cggattatcg
     9241 gagttgaagg ccgctacgtt cggcatcagt tttttcaact cttcatatgc cgcttcgatc
     9301 tctttaggat cggtagtgtt accggaataa cctagcttgc gcagcgccat ctggaagact
     9361 tctcgcgcat cgtcggttaa aagcaggctg tttttatatt ccggtttcca caaatcagcc
     9421 cagctggtaa tggtttttgg atcgatagca tcgctgttca cgccaatcgc cgttgcgccc
     9481 cagatatacg gaacagaata atcgttgttg gggtcaaacg gtttgttgag catttccgga
     9541 tcgaggttgt ggaaattggt taatttcgac ttatcgatct tctggatcat gccttctttg
     9601 cgcattttgt cgacatagta tgtagaagga acaaccaggt catacgcgcc atctttatag
     9661 gttttgagtt tggcatacat ggtttcgttc gactcgtagg tcgaataaat caccttaatg
     9721 cctgtctctt tagtgaactg ttccagcagg cccggcggta catactcagt ccagttatag
     9781 aaatagagcg tgtcgttgtc ggaggcatga gcggcactca tacccagcgc cagggcgcct
     9841 gccgcgagca ggtggcgtga ccattttttc atttaacgtc ccctgaatta cgggccttat
     9901 cggcccttgg ttttatcacg agcaataagc tggctggcaa tgaccattac cagagacagc
     9961 accaataaaa cggtcgccag cgcgttcact tctggtgaaa cgccgacttt taccatggaa
    10021 taaatcttta agggtaaaat ttcatagccc ggcccggtga caaacgacga gactactaca
    10081 tcgtccatcg acaacgtaaa gctcagcaac cagcccgccg ccaccgccgg catcgccagc
    10141 ggcagaatga ttttgcgtaa aatcgttacc tcactggccc ccaggtcttt tgcggcttcc
    10201 agcattctga catcaaagcc tttcaggcgc gaatagaccg tgacgaccac aaacggcagg
    10261 ctaaaggtga tgtgcgagaa cagcaacgac caaaagccca gttgaatgcc gagtaacata
    10321 aacagcacca gcagggagat cgccatcacg atatccggcg acatcattac tacaaacagc
    10381 atcccgctga cgaatggctt cccgcgaaag cggtagcgat aaagcgctac cgcggttaac
    10441 gagccaatca acgtggcgaa ggtcgctgag aaaatcgcca tcgtcagtga atgttgagcg
    10501 gcctgtaaca gactgtcgtt attgaccagt agttcgtacc atttagtggt aaagccctgc
    10561 cagttaatgc cgaaccgcga actgttgaag gagttcacga tcagaataat gatgggaata
    10621 tacagatacg catagatggc agtcatgaaa ccgccacgga gcagccgacc gatcattcaa
    10681 gttccacctt cttattcaga ggatggggtg cttttagagt attgaaaatg atcaattttt
    10741 tctcttctcc aaaatctctc caaaacgtct cgcggttatc agcagccagg aagaagcaag
    10801 ctgccgcttg aagccgcgaa ttttacaaca aattgccaga cgagcgggaa aaaaaggcca
    10861 tttaaatgac tattctcatc cgatccggtc atatgcggca ttattgcgcc aggcaagagg
    10921 ttactctgta ggcaaacatg aagtacgtga gtaaaccctg aacgtgacgt ctgagaaagc
    10981 gtcgtctgat tttataaaaa acaacataaa tagccgcttt gttgttctga gcgaacgtgt
    11041 agcgtggtta actgttcttc cgccattttt tgtatagact ggggggctat tctaaaaatg
    11101 gcgtgaaaaa cctgatcaga gatggcttcg actatctcag ctaacatgct taggctggcg
    11161 ctgggatccg ttacaaggaa cgcctgaaac gtcttatcc
//
LOCUS       DAJVBX010000160        11042 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.160, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000160 DAJVBX010000000
VERSION     DAJVBX010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 11042)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11042)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11042
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.160"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(5..2257)
                     /gene="katE"
                     /locus_tag="OPV72_003440"
     CDS             complement(5..2257)
                     /gene="katE"
                     /locus_tag="OPV72_003440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catalase HPII"
                     /protein_id="HCR9915647.1"
                     /translation="MSHNEKSPHQSPVHDTRESQPGLDSLAPSDGSHRPTPEPTPPGA
                     QPTAPGSLKAPETANDKLTALDAFRKGSENYALTTNQGVRIADDQNSLRAGSRGPTLL
                     EDFILREKITHFDHERIPERIVHARGSAAHGYFQPYKDLSDITKAAFLCDPQKITPVF
                     VRFSTVQGGAGSADTVRDIRGFATKFYTEEGIFDLVGNNTPIFFIQDAHKFPDFVHAV
                     KPEPHWAIPQGQSAHDTFWDYVSLQPETLHNVMWAISDRGIPRSYRTMEGFGIHTFRL
                     INAQGKATFVRFHWKPLAGKASLVWDESQKLTGRDPDFHRRDLWEAIEAGDFPEYELG
                     LQLIAEEDEFKFDFDLLDPTKLIPEELVPVQRVGKMVLNRNPDNFFAENEQAAFHPGH
                     IVPGIDFTNDPLLQGRLFSYTDTQISRLGGPNFHEIPINRPTCPYHNFQRDGMHRMDI
                     DTNPANYEPNSINDNWPRETPPAPKRGGFESYQERVDGNEIRERSPSFGEYYSHPRLF
                     WLSQTPIEQQHIIDAFSFELGKVARAYIRERVVDQLAHIDVTLAQGVAHNLGFALTHE
                     QTQIAPPPDVNGLKKDPALSLYAVPDGDVKGRVVAILLNDKVNAAELLTIFQALKAKG
                     VHVKLLYSRMGEVTADDGSTLTIAATFAGAPSLTVDAVIVPCGNIADIESCGDARYYL
                     LEAYKHLKPIALAGDARRFKALLNIDSQGEEGLVEADNVDHHFMDTLLTLMAAHRVWS
                     RAGKINAIPA"
     gene            2474..2716
                     /gene="cedA"
                     /locus_tag="OPV72_003441"
     CDS             2474..2716
                     /gene="cedA"
                     /locus_tag="OPV72_003441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division activator CedA"
                     /protein_id="HCR9915648.1"
                     /translation="MMKPLRQQNRQIISYIPRVEPAPPEHAIKMDTFRDVWILRGKYV
                     AFVLTGESFQRSPAFSVPESAQRWANQVRQENEIAD"
     gene            complement(2819..4210)
                     /gene="tcyP"
                     /locus_tag="OPV72_003442"
     CDS             complement(2819..4210)
                     /gene="tcyP"
                     /locus_tag="OPV72_003442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystine/sulfocysteine:cation symporter"
                     /protein_id="HCR9915649.1"
                     /translation="MNFPLIANIAVFVILLFVLAQARHKQWSLAKKVLVGLVMGVVFG
                     LALHTIYGADSQVLKDSIQWFNIVGNGYVQLLQMIVMPLVFASILSAVARLHNASQLG
                     KISFLTIGTLLFTTFIAALVGVLVTNLFGLTAEGLVQGGAETARLNAIETSYVGKVAD
                     LSVPQLVLSFVPKNPFADLTGANPTSIISVVIFAAFLGVAALKLLKDDAPKGERVLVA
                     IDTLQSWVMKLVRLVMQLTPYGVLALMTKVVAGSNLQDIIKLGSFVVASYLGLAIMFV
                     VHGILLGVNGISPLKYFRKVWPVLTFAFTSRSSAASIPLNVEAQTRRLGVPESIASFA
                     ASFGATIGQNGCAGLYPAMLAVMVAPTVGINPLDPVWIATLVGIVTVSSAGVAGVGGG
                     ATFAALIVLPAMGLPVTLVALLISVEPLIDMGRTALNVSGSMTAGTLTSQWLKQTDKT
                     ILDSEEDAELAHR"
     gene            complement(4347..4946)
                     /locus_tag="OPV72_003443"
     CDS             complement(4347..4946)
                     /locus_tag="OPV72_003443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460287.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HCR9915650.1"
                     /translation="MGFIMTAEGHLLFSIASAVFAKNAELTPALAHGDWWHIIPSAIL
                     TCLLPDIDHPKSFLGQRLKWVSKPIARAFGHRGFTHSLLAVFALLATFYLKVPDTWII
                     PADALQGMVLGYLSHIVADMLTPAGVPLLWPCRWRFRLPILAPRKGNQLERFLCMALF
                     AWAVWMPQSMPENNVIRWSSQMITILQMQFNRFINHQID"
     gene            complement(5084..5752)
                     /gene="hxpB"
                     /locus_tag="OPV72_003444"
     CDS             complement(5084..5752)
                     /gene="hxpB"
                     /locus_tag="OPV72_003444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexitol phosphatase HxpB"
                     /protein_id="HCR9915651.1"
                     /translation="MSTPRQILAAIFDMDGLLIDSEPLWDRAELDVMASLGVDITRRH
                     ELPDTLRLRIDMVVDLWFAQQPWNGPDRQEVTNRVIARAITLIEETRPLLPGVREAVA
                     LCKAQGLLVGLASASPLHMLEKVLTMFELRDSFDALASAEKLPYSKPHPQVYLDCAAK
                     LGVDPLTCVALEDSVNGLIAAKAARMRAIVVPAEENQHDPRFALANVKLNSLTELTAA
                     HLLG"
     gene            5901..6437
                     /locus_tag="OPV72_003445"
     CDS             5901..6437
                     /locus_tag="OPV72_003445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YniB family protein"
                     /protein_id="HCR9915652.1"
                     /translation="MTYQQAGRIAILKRVVGWVIFIPALLSTLISVLKFMYAHSEKQE
                     GINAVMLDFTHVMIDMMRVNTPFLNVFWYNSPTPNFQGSLNIGFWLIFILIFVGLAMQ
                     DSGARMSRQSRFLREGVEDQLILEKAKGAEGLTREQIESRIVVPHHTIFLQFFPLYIL
                     PVIIIVLGYFFFSLLGFM"
     gene            complement(6480..7340)
                     /locus_tag="OPV72_003446"
     CDS             complement(6480..7340)
                     /locus_tag="OPV72_003446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HCR9915653.1"
                     /translation="MWQAISRLLSEQVGEGEIELRNELPGGEVHAAWHLRYAGHDFFV
                     KCDEREMLRGFTAEADQLELLSRSKTVVVPKVWAVGSDRDYSFLVMDYLSPRPLDAHN
                     AFILGQQLARLHQWSDQPQFGLDFDNALSTTPQPNTWQRRWSTFFAEQRIGWQLELAA
                     EKGITFGNIDAIVEHVQQRLASHQPQPSLLHGDLWSANCALGPDGPYIFDPACYWGDR
                     ECDLAMLPLHTDQPPQIYDGYQSVSPLPLDFLDRQPIYQLYTLLNRARLFGGQHLATA
                     QKAMDRLLAV"
     gene            complement(7447..7737)
                     /gene="ghoS"
                     /locus_tag="OPV72_003447"
     CDS             complement(7447..7737)
                     /gene="ghoS"
                     /locus_tag="OPV72_003447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type V toxin-antitoxin system endoribonuclease
                     antitoxin GhoS"
                     /protein_id="HCR9915654.1"
                     /translation="MASGDITRYVITVTFHEDSLTEINELNNHLTRSGFLLTLTDDEG
                     NVHELGTNTFGFVSAQSADEIKALVAGLAKSALDKDVDITVATWEAWSKNAQ"
     gene            complement(7834..8766)
                     /gene="pfkB"
                     /locus_tag="OPV72_003448"
     CDS             complement(7834..8766)
                     /gene="pfkB"
                     /locus_tag="OPV72_003448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase II"
                     /protein_id="HCR9915655.1"
                     /translation="MVRIYTLTLAPSLDSATITPQIYPEGKLRCSAPVFEPGGGGINV
                     ARAIAHLGGTATAIFPAGGATGEHLVALLADENVPVSTVDAKDWTRQNLHVHVESSGE
                     QYRFVMPGATLDDDEFRQLEEQVLEIESGAILVISGSLPPGVKVEKLTQLISAAQKQG
                     IRCIIDSSGDALTAALALGDIELVKPNLKELSALVNRDLTQPDDVRKAAQELVQSGKA
                     RRVVVSLGPQGALGIDSENCIQVVPPPVKSQSTVGAGDSMVGAMTLKLAQDASLEEMV
                     RFGVAAGSAATLNQGTRLCSHDDTQKIYAYLSAQ"
     gene            9055..9813
                     /locus_tag="OPV72_003449"
     CDS             9055..9813
                     /locus_tag="OPV72_003449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdiY family protein"
                     /protein_id="HCR9915656.1"
                     /translation="MKLLKAVPAVVMLAGGVFASLYAAADDSVFTVMDDPSTAKKPFE
                     GNLNAGYLAQSGNTKSSSLTADTAMTWYGQRTAWSLWGNASNTSSNDERSSEKYAVGV
                     RNRFNMTDYDYTFGQASWLTDRFNGYRQRDVLTAGYGRQFLNGPVHSFRFEFGPGVRY
                     DEHTDDTTETQPLGYASGSYAWQLTDNAKFTQGVSVFGAEDTTLNSETALNVAINEHF
                     GLKVGYNLTWNSQPPESAPEHTDRRTTVTLGYKM"
     gene            complement(9862..10821)
                     /locus_tag="OPV72_003450"
     CDS             complement(9862..10821)
                     /locus_tag="OPV72_003450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid A deacylase LpxR family protein"
                     /protein_id="HCR9915657.1"
                     /translation="MNKYSYCATMIAAILSTTTMANASSLAISVANDDAGIFQPSLNA
                     LYGHKAADRGDYTAGLFLGYSHDLTDASQLSFHIAQDIYSPSGANKRKPEAVKGDRAF
                     SAFLHTGLEWNSLATNWLRYRLGTDIGVIGPDAGGQEVQNRAHRIIGAEKYPAWQDQI
                     ENRYGYTAKGMVSLTPAIDILGVNVGFYPEVSAVGGNLFQYLGYGATVALGNDKTFNS
                     DNGFGLLSRRGLIHTQKEGLIYKVFAGVERREVDKNYTLQGKTLQTKMETVDINKTVD
                     EYRVGATIGYSPVAFSLSLNKVTSEFRTGDDYSYINGDITFFF"
BASE COUNT         2700 a         2832 c         2856 g         2654 t
ORIGIN      
        1 ccgtttatgc aggaatcgcg ttaattttcc ccgcacgcga ccagacacgg tgtgccgcca
       61 tcagcgtcag cagagtgtcc ataaagtggt ggtcaacgtt atctgcctca acaagtcctt
      121 cttccccctg gctatcaatg tttaaaagcg ccttaaaccg tcgggcgtcg cctgccagtg
      181 cgatgggctt cagatgtttg taggcttcca gaaggtagta acgggcatcg ccgcaactct
      241 cgatatcggc aatattgccg cacggtacta ttaccgcatc gaccgttagc gacggcgcgc
      301 cggcaaaggt tgccgcaata gttaatgttg aaccgtcatc agccgttact tcccccatcc
      361 gtgaatagag cagttttacg tggacgcctt tggcttttaa agcctgaaaa atggtcaaca
      421 gttcggcggc gttaaccttg tcgttcagca gaatagcgac cactcggcct ttaacatcgc
      481 cgtccggcac cgcatacagg ctgagcgccg gatctttttt cagaccgttg acatcaggag
      541 gcggggcaat ttgcgtttgc tcatgggtga gtgcaaaacc gagattatgc gcgacgccct
      601 gagccagcgt gacatcaata tgcgctaact gatcgaccac ccgctcccga atatacgcgc
      661 gggcgacttt acccagctca aagctgaacg cgtcaataat atgctgctgt tctatcggcg
      721 tctgactgag ccagaacagg cgaggatgcg agtaatattc accgaaagag gggctgcgtt
      781 cgcggatttc attaccatcc acgcgttcct ggtatgattc gaagccgccg cgttttggcg
      841 ctggcggcgt ttcgcgtggc cagttgtcat taatggagtt tggttcatag ttcgccggat
      901 tggtgtcgat atccatccgg tgcataccgt cacgctggaa gttatggtag gggcaggtag
      961 ggcggttaat cggaatttcg tggaagtttg gcccgcccag acgactgatt tgcgtgtcgg
     1021 tataagagaa cagacgcccc tgtaacagcg gatcgttggt aaaatcaatg ccgggaacaa
     1081 tatgtcctgg atgaaatgcc gcctgttcgt tttcagcgaa aaagttatcc ggattacggt
     1141 ttaacaccat tttgccgacg cgttgtactg gcaccaactc ttccggaatc agtttggtcg
     1201 gatcgagcag atcaaaatcg aatttaaatt catcctcttc ggcaatgagt tgtaggccca
     1261 gctcgtattc cgggaaatcg cccgcttcga tggcctccca cagatcccgg cggtgaaaat
     1321 ccggatcgcg accggtcagt ttttgtgact catcccatac cagcgaggct ttacctgcca
     1381 acggtttcca gtggaaacgg acaaaggtcg ctttcccttg tgcattgatc agacggaagg
     1441 tgtgaatgcc gaacccttcc atcgtccgat aactccgtgg aataccgcga tccgatattg
     1501 cccacatgac gttgtgcagc gtctcaggct gtaaggaaac atagtcccag aaggtgtcgt
     1561 gcgcgctctg cccttgcgga atagcccaat gtggttcggg cttaacggcg tgcacaaaat
     1621 ccggaaactt atgcgcatcc tggataaaaa agatcggcgt gttattaccg acgagatcga
     1681 aaattccctc ttcggtataa aatttggtcg caaaaccgcg gatatcacgt acggtatcag
     1741 cagaccccgc gccgccctgt actgtcgaaa agcgaacaaa gaccggggta attttctgtg
     1801 gatcgcacag aaacgcggct ttcgtgatgt cgctcaggtc tttatatggc tggaaatagc
     1861 cgtgcgctgc agatccgcgg gcgtgaacga tcctctccgg gatacgctca tggtcaaagt
     1921 gggtaatttt ctcgcgcagg ataaaatctt ccaacagcgt agggccacgg ctgccggcgc
     1981 gaagagaatt ttgatcgtcg gcgatgcgca cgccctgatt ggtggtcagc gcataatttt
     2041 cgctgccttt acgaaaggcg tcgagggcgg tgagcttatc attcgcggtc tcgggcgctt
     2101 ttaagctgcc gggggccgtt ggttgcgcgc ccggcggcgt cggttctggc gtggggcgat
     2161 gtgaaccgtc tgacggtgcc agggagtcca ggccgggctg tgattcacgg gtatcatgca
     2221 cgggggactg atggggggat ttttcattat gcgacattga actcgtctcc tgctttcatc
     2281 actgaaatgg gcgtggtagt agtcaaaatc actctaacta tagaacattt cagcaattat
     2341 gccgggggag agcggaacgg cagacagggt acaacgggga aatcgcacgc gcggaacagg
     2401 acgtcggggg cgaagatcgg ctaaaatagt gtttttctga tttttagcct tagcctcttt
     2461 tagtgaagca ttaatgatga aacctcttcg ccagcaaaat cgccagatta ttagctatat
     2521 tccgcgtgtt gaacccgcgc cgccggaaca tgcgataaaa atggatacgt ttcgcgacgt
     2581 ctggatactg cgcggtaaat atgttgcctt tgttctgacg ggggagtcat ttcaacggtc
     2641 gcccgccttt agcgtgccag aatcggcgca acgttgggcg aatcaggttc gccaggaaaa
     2701 cgaaatcgct gactaagaaa aaaacaaaac gccggtactg gagaccggcg tttttagtga
     2761 cagacatttt gagttgccga tcgtcgtgtc tcagacgatg tgaactcccg ataatgtatt
     2821 atcgatgcgc cagttcagcg tcttcttcgc tatcgagaat ggttttatcg gtctgcttca
     2881 gccactggct ggtcagcgta cccgcggtca ttgagccgct cacgttcagt gcggtacggc
     2941 ccatatcaat caacggttcg acggagatta acagcgcgac cagcgtgacc ggtaagccca
     3001 tggcaggcag cacaatcagc gcggcgaagg tcgcgccgcc gccaacgccg gcaacacccg
     3061 ccgaacttac ggtaacgata cccaccagcg tggctatcca tacggggtct aaggggttga
     3121 tgccgaccgt cggcgcaacc attaccgcta acatcgcagg ataaagaccg gcacaaccgt
     3181 tttggccgat ggtcgcgcca aaagaggcag caaagctggc gatggactcc ggcacgccca
     3241 gacggcgggt ttgcgcttcg acattaagtg gaatggaggc ggcgctggag cggctggtaa
     3301 aggcaaatgt cagcaccggc cacaccttgc ggaaatattt cagcgggcta atcccgttca
     3361 cgcccaatag tatgccgtga accacaaaca ttatcgccag accaagatat gacgctacca
     3421 cgaagcttcc aagcttaatg atgtcctgca aattagagcc ggcaaccact ttcgtcatca
     3481 gcgccagtac gccgtaaggc gtaagttgca tcaccagacg caccagcttc atcacccagc
     3541 tttgcagggt atcgatagca acaagcacac gctcgccttt tggcgcatca tctttcagca
     3601 gtttaagcgc ggccacgccc aggaatgcgg cgaaaatcac cacgctgata atagacgtag
     3661 gatttgcgcc agtcagatcc gcaaacggat ttttcggtac aaaagacagc accagttgcg
     3721 gcacgctgag atcggccact ttgccgacat agctcgtctc aatggcattc agacgcgcgg
     3781 tttccgcgcc gccctgaacc agaccttccg ccgtcagtcc gaacagattg gtgaccagca
     3841 cgcccaccag cgctgcgata aaggtagtaa acagcagcgt gccgatagtc agaaaactga
     3901 ttttccccaa ttgagaggcg ttatgcagtc gtgccacggc gcttaaaata gaggcgaata
     3961 ccagcggcat cacaatcatt tgtagcaatt gcacataacc gttgccgaca atattgaacc
     4021 actgaatgga gtcttttaac acctgactgt cagcgccata aatggtgtgc agggccagac
     4081 caaagaccac gcccatcaca aggccgacaa gcactttttt agccagactc cactgtttat
     4141 gacgggcctg cgccagtaca aacagcagaa tgacgaacac cgcaatgttc gcaattaatg
     4201 gaaaattcat ccccgttctc ctgatttttt tattatgaag cgctgtgttt tagcgattct
     4261 gttcgcgcaa gattagcaga actgtgagct ggctcttata ttcaaatgga atggtttata
     4321 cctaaaatga ctttggcgtt gatttactaa tcaatctggt gatttataaa acgattgaac
     4381 tgcatttgca ggatagtgat catctgcgaa gaccagcgta tgacgttgtt ttccggcatg
     4441 gattgcggca tccacaccgc ccaggcaaac aacgccatac ataaaaatcg ctccagttga
     4501 ttgcccttgc gcggcgccag aataggcagg cggaaacgcc agcgacacgg ccacagtaag
     4561 ggaacgcctg cgggggtaag catatccgcg acgatatggc ttaaatagcc gagtaccatg
     4621 ccttgcagcg catccgccgg gataatccac gtatccggaa ccttgagata aaaggtcgcc
     4681 agtagggcaa agaccgccag cagactatgg gtaaaccccc ggtgaccgaa tgcgcgggcg
     4741 atcggtttcg atacccattt caggcgctga ccaagaaaag atttggggtg atcgatatcc
     4801 ggcagcagac aggtcaaaat agccgaagga ataatatgcc accagtcgcc gtgcgcaagg
     4861 gcgggcgtta actcggcatt cttggcgaaa accgcgctgg ctatagaaaa aagaagatgt
     4921 ccttccgccg tcatgataaa acccattaaa ctgtcaattc atacagtata gggtttttat
     4981 acagtaggcg gaagtggtga cgttgtaact ctttgtctct gtcaaagccg cttgccgtct
     5041 ggctcagcgg ctaattgccc gttgactttg tttcggaaac atcttaaccg agtagatgcg
     5101 ccgccgtcag ctctgtcagt gagttaagtt tgacattcgc cagcgcaaag cgcggatcat
     5161 gctggttttc ttctgctggc accacaatgg cgcgcattcg cgccgccttt gccgcgatta
     5221 aaccattcac cgaatcctcc agcgccacgc aggttaatgg atcaacgcct aatttggccg
     5281 cacaatccag atagacctgc gggtgcggtt tgctgtaggg caatttttcc gcagaggcca
     5341 gcgcgtcaaa actgtcgcgc agttcaaaca tggtgagcac tttttccagc atatgcagcg
     5401 gcgatgccga ggcaagcccc actaatagcc cctgcgcttt acacagcgcc acagcttcgc
     5461 gcacacccgg caaaagaggg cgcgtctctt cgataagcgt aatcgcgcgg gcaataacac
     5521 ggtttgtcac ttcctggcga tcggggccgt tccacggttg ctgcgcaaac cagagatcga
     5581 caaccatatc aatgcgtagc ctaagcgtgt ctggcagttc atggcgccga gtaatatcta
     5641 cgcctaaact tgccatcacg tccagttcag cgcgatccca gagcggttcg gaatcgatca
     5701 atagtccatc catatcgaaa attgcagcaa gaatttgacg tggggttgac atcacaacct
     5761 ctcctgttga gattaaaaaa taacgaatta agcgttcatt atgaccatgt tcttagtata
     5821 tcgcccttaa agatcaggcg aaaacgggaa tcaacaggta gacttaggcc aaaacgacgc
     5881 gtctttatca aggggaactc atgacgtatc aacaagctgg acgcattgca atcctaaaaa
     5941 gagttgttgg gtgggttatt tttattccgg cactgctttc cacgctcatc tcagtcctta
     6001 aatttatgta tgcgcacagt gaaaagcagg aggggataaa tgcggtaatg ctggatttta
     6061 cccacgtaat gatagacatg atgcgcgtga atacgccgtt tctgaatgtt ttttggtaca
     6121 actcgccgac gccgaatttt cagggaagcc tgaatatcgg tttctggctc atttttattc
     6181 tgatttttgt cgggctggcg atgcaggatt ccggcgccag aatgagccgc cagtcacgtt
     6241 ttttacgtga aggcgtggaa gatcagttga tcctggaaaa agcaaaaggc gcggaaggac
     6301 taacgcgtga gcagatagag tcacgtatcg tggtgccgca ccataccatc tttttacagt
     6361 ttttcccgct ctatattttg ccggtcatta ttatcgtgct cggctacttt ttcttttcct
     6421 tgttaggttt catgtaaact gaaaaatgcc ggatagcccg tatccggtgt gggctgtacc
     6481 tataccgcaa gcagccgatc catcgctttt tgcgcagtag ccaggtgctg accgccaaac
     6541 agccttgccc gattaagcag ggtgtagagc tggtaaatcg gctgcctgtc gagaaaatcc
     6601 agcggtagcg gcgaaacgga ctgatagccg tcataaatct gcggtggctg atcggtatgc
     6661 agcggcagca tcgccagatc gcattctctg tcgccccaat agcaggctgg atcgaagata
     6721 taggggccgt cagggccaag cgcgcagttc gccgaccata gatcgccatg caaaagagaa
     6781 ggctgcggtt gatgcgacgc cagacgttgc tgaacatgtt caacaatggc gtcaatatta
     6841 ccaaaggtaa tgcctttttc cgcggcgagt tcaagctgcc agccaatgcg ctgttcggcg
     6901 aaaaaagtcg accaacggcg ttgccaggta ttcggctgcg gcgtggtaga gagcgcgtta
     6961 tcaaaatcga ggccgaattg aggttggtcg ctccattggt gcaggcgcgc cagctgttgc
     7021 ccaagaataa acgcattatg ggcatccagc gggcggggcg agaggtagtc catgactaaa
     7081 aagctgtaat cccgatccga acctaccgcc cataccttag gcacaacaac ggttttactg
     7141 cgggagagca gctccagctg atcggcttca gcggtaaaac cgcgaagcat ttctcgttca
     7201 tcgcacttca cgaaaaaatc atggccggca taacgtaaat gccatgcggc atgaacttct
     7261 ccgcctggca gttcattacg cagttcgatt tcgccttcac cgacttgctc gcttaaaaga
     7321 cgactgatag cttgccacat aatgtctctc cccacgttgt ctgccagatc ataaggttag
     7381 cgcaaaaatg cggttaaaaa atacgaacta acgcacatcg cggacgcgcc gcggcgggaa
     7441 tggcacttat tgtgcgtttt tactccacgc ctcccaggtc gccacggtaa tgtcgacatc
     7501 cttatctaac gcgcttttcg caagtccggc gacaagcgct ttgatttcat cagcgctctg
     7561 agcgctaaca aagccaaacg tattggtgcc gagctcatgc acattccctt catcgtccgt
     7621 taatgtcagc aaaaaaccgc tgcgcgtcag atggttattg agttcgttaa tctcggtcag
     7681 ggaatcttca tggaaggtta cggtaataac ataacgggta atatcgccac tggccatcgt
     7741 tcacctcgtt gggagcaact gtgtttttaa cagcggcgga tgcgccgccc gttaaccgat
     7801 tttccggtat ccccctcggc gagggggaaa cgattattgc gcggaaagat aggcgtatat
     7861 tttttgggta tcgtcatgag aacacagacg cgtaccttga ttgagcgtag cggcgctgcc
     7921 tgccgccaca ccgaagcgca ccatctcttc cagcgacgcg tcttgcgcca gttttaacgt
     7981 catcgcgccc accatactgt cgcctgcgcc gacagtactt tgacttttca ccgggggagg
     8041 aacaacctgg atgcaattct cactgtctat gcccagcgcc ccttgcggcc ccagagagac
     8101 cactacccgg cgagccttgc cactttgcac taattcctgg gccgctttac gcacatcatc
     8161 aggctgcgtc agatcgcgat tgactaacgc gctcaattct ttcaggttag gtttcaccag
     8221 ttcgatatcg ccaagcgcca acgcagcggt gagcgcgtcg ccagagctat caataatgca
     8281 gcgaatgcct tgcttctgcg cggcggaaat cagttgcgtg agtttctcga ccttaacgcc
     8341 gggcggaagg ctgccgctga taaccagaat tgccccggat tcaatttcca gtacctgttc
     8401 ttcaagctgg cgaaattcgt catcgtccag cgtggcgccg ggcataacaa aacgatattg
     8461 ttcgccgctg gactcgacgt ggacgtgcag gttctgacgc gtccagtcct tcgcatcgac
     8521 ggtagacacg gggacatttt cgtcagccag tagtgcgacc agatgttcgc cggtagcgcc
     8581 gccagccggg aaaattgcgg tcgcggtgcc gccaagatgc gcaatggcgc gagcgacatt
     8641 aatacccccg ccgccgggtt cgaataccgg cgcggagcac cgcagtttac cttcgggata
     8701 aatttgcggc gtgattgttg cgctatcgag agagggcgca agcgtcaacg tatagatacg
     8761 taccatcgtt acctcctgtt aggctgattt cagtctggca cttaatcccc ggaaagtgaa
     8821 ggaattaaca atatgatttt ccggatcttt atttaaagaa gtacgatgta aagttatata
     8881 aataaatgaa tgcttcggga gggttcttat tcaaaaaatg aaatagtaat tgattgctat
     8941 gttattcggg gcttcttata attcgctacc tttccagggg cgtttgtcat tgatccctat
     9001 gaaagtttcc gggaccgtcg tggtctcttt tttagttgta cggactctat ataaatgaag
     9061 cttttgaagg cagtacccgc tgtagttatg ctggcgggtg gcgtgttcgc gtctctgtat
     9121 gccgccgccg atgattccgt ttttactgtc atggatgatc cctccaccgc gaaaaaacct
     9181 tttgaaggta atctgaatgc gggctacctt gctcagtcag gcaatactaa aagttcttcc
     9241 ttaacggctg acacggcgat gacctggtat ggacaacgta ccgcctggtc attatggggc
     9301 aatgccagca atacctcctc taatgatgaa cgctcttcag aaaaatatgc ggtaggcgtg
     9361 cgtaaccgtt ttaatatgac ggattatgat tatacctttg gccaggccag ttggctgaca
     9421 gaccgtttca acggttatcg tcagcgcgac gtactgaccg ccggttacgg gcggcagttc
     9481 cttaatggtc cagtgcacag cttccgtttt gaattcggtc caggggttcg ctatgacgaa
     9541 catacggacg ataccactga aacgcagccg ttgggttatg cttccggcag ctatgcctgg
     9601 cagttaactg acaatgctaa gtttacacag ggggtgtcag tatttggcgc agaagacacc
     9661 acactaaatt cggaaacagc cctcaatgtc gccattaacg aacattttgg tctaaaggtg
     9721 gggtataatt taacgtggaa ctcgcagccg cctgaatcag cgcctgaaca taccgatcgc
     9781 cgcactacgg taacgctggg ctataagatg taatattgcg ccgggttacg ttacgtaacc
     9841 cggttattcc gtggtgacgc ctcagaagaa gaaggtgatg tcgccgttga tataagaata
     9901 gtcgtctccg gtgcgaaatt ccgacgtgac tttgtttaaa gaaagagaaa atgcgacggg
     9961 agaatagccg atggtggcac cgacgcgata ttcatccacg gttttattaa tatccaccgt
    10021 ttccattttt gtttgcagcg ttttcccctg taacgtgtag tttttatcaa cttccctgcg
    10081 ctcaacgcca gcaaatactt tatagatcaa tccctctttt tgagtgtgta ttaaccctcg
    10141 gcgggacaat aacccaaacc cattatcaga gttgaaggtc ttatcatttc ccagcgcaac
    10201 ggttgcgccg taccccaaat actggaagag attgccgccg acagcagaga cttctggata
    10261 gaagcccaca ttgacaccca gaatatcaat agctggcgta agggagacca ttccttttgc
    10321 cgtgtaacca taacggtttt caatttgatc ctgccaggca gggtattttt ctgcgcctat
    10381 tattcgatgc gcccgattct gaacctcctg accgcctgcg tcaggaccaa taacgccgat
    10441 atcggtacct aaacgataac gtaaccaatt ggtggctaat gaattccact ccagtccggt
    10501 atgaagaaag gcgctgaacg cgcggtcgcc tttgacggct tcaggctttc ttttattggc
    10561 gccagatgga gaataaatat cttgcgcgat atgaaaagag agttgactgg cgtcagtgag
    10621 atcgtggctg tagcctaaaa agagcccggc agtataatca ccccggtctg cagccttgtg
    10681 cccgtaaagg gcatttaagg atggttgaaa tatacctgca tcatcattcg ccactgaaat
    10741 agcaaggcta ctggcattgg ccattgtggt cgtactgagt atggcggcaa tcatcgttgc
    10801 gcaatagctg tatttgttca ctttttaccc ctgaatatga aagtgaatac tcttattttt
    10861 acaaagtaat aagcacagca gcatgatgcg cagtgcttat taaaccttta aatataacta
    10921 aactcctgcc agcagcgagt cattgagagg atacgttgcc ttaatgttga aaaatggtgt
    10981 taaaaaacat gcgccagata ttattgaata tccatttttc attcgctatc tgagtgcgag
    11041 aa
//
LOCUS       DAJVBX010000161        10955 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.161, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000161 DAJVBX010000000
VERSION     DAJVBX010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 10955)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10955)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10955
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.161"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(222..2795)
                     /gene="clpB"
                     /locus_tag="OPV72_003451"
     CDS             complement(222..2795)
                     /gene="clpB"
                     /locus_tag="OPV72_003451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002461515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HCR9915658.1"
                     /translation="MRLDRLTNKFQLALADAQSLALGHDNQFIEPLHLMSALLNQEGG
                     SIRPLLTSAGINAGQLRTAIDQALSRLPQVEGTGGDVQPSSELVRVLNLCDKLAQKRG
                     DNFISSELFVLAALESRGTLTDLLKSAGATTANITQAIEQMRGGESVNDQGAEDQRQA
                     LKKYTVDLTERAEQGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEG
                     LAQRIINGEVPEGLKGRRVLALDMGALVAGAKYRGEFEERLKGVLNDLAKQEGNVILF
                     IDELHTMVGAGKADGAMDAGNMLKPALARGELHCVGATTLDEYRQYIEKDAALERRFQ
                     KVFVAEPSVEDTIAILRGLKERYELHHHVQITDPAIVAAATLSHRYIADRQLPDKAID
                     LIDEAASSIRMQIDSKPEELDRLDRRIIQLKLEQQALMKESDEASKKRLDMLNEELDD
                     KERQYSELEEEWKAEKASLSGTQTIKAELEQAKIAIEQARRVGDLARMSELQYGKIPE
                     LEKQLEAATQSEGKTMRLLRNKVTDAEIAEVLARWTGIPVSRMLEGEREKLLRMEQEL
                     HSRVIGQNEAVEAVSNAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKALANFMFD
                     SDDAMVRIDMSEFMEKHSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKA
                     HPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNLGSDLIQERFGELDYGRMKEM
                     VLGVVSQNFRPEFINRIDEVVVFHPLGEQHIASIAQIQLQRLYKRLEERGYEIHISDE
                     ALKLLSANGYDPVYGARPLKRAIQQQIENPLAQQILSGELVPGKVIRLEANDDRIVAV
                     Q"
     gene            complement(2925..3656)
                     /gene="pgeF"
                     /locus_tag="OPV72_003452"
     CDS             complement(2925..3656)
                     /gene="pgeF"
                     /locus_tag="OPV72_003452"
                     /EC_number="1.10.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphenol oxidase"
                     /protein_id="HCR9915659.1"
                     /translation="MNALIVPQWPLPKGVAACSSTRIGGVSLSPYDSLNLGAHCGDNP
                     EHVEENRKRLFAAGNLPSKPVWLEQVHGKNVLRLTGEPYASKRADASYSNTPGTVCAV
                     MTADCLPVLFCNREGTEVAAAHAGWRGLCEGVLEETVTCFADKPENIIAWLGPAIGPA
                     AFEVGPEVRDAFLAKDAQADSAFLPHGEKFLADIYQLARQRLANTGVEHVYGGDRCTF
                     SESETFFSYRRDKTTGRMASFIWLI"
     gene            complement(3653..4633)
                     /gene="rluD"
                     /locus_tag="OPV72_003453"
     CDS             complement(3653..4633)
                     /gene="rluD"
                     /locus_tag="OPV72_003453"
                     /EC_number="5.4.99.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017383977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(1911/1915/1917) synthase
                     RluD"
                     /protein_id="HCR9915660.1"
                     /translation="MAQRVQLTATVSENQLGQRLDQALAEMFPDYSRSRIKEWILNQR
                     VLVNGQLCDKPKEKVLGGERVAIDAEIDEEIRFEAQDIPLDIVYEDDDILVINKPRDL
                     VVHPGAGNPDGTVLNALLHYYPPIADVPRAGIVHRLDKDTTGLMVVAKTVPAQTRLVE
                     SLQLREITREYEAVAIGHMTAGGTVNEPISRHPTKRTHMSVHPMGKPAVTHYRIMEHF
                     RVHTRLRLRLETGRTHQIRVHMAHITHPLVGDQVYGGRPRPPKGASEEFISTLRKFDR
                     QALHATMLRLYHPVSGIEMEWHAPIPQDMVDLIDAMRADFEDHKDDVDWL"
     gene            4765..5502
                     /gene="bamD"
                     /locus_tag="OPV72_003454"
     CDS             4765..5502
                     /gene="bamD"
                     /locus_tag="OPV72_003454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamD"
                     /protein_id="HCR9915661.1"
                     /translation="MTRMKYLVAAATLSLFLAGCSGSKEEVPDNPPNEIYATAQQKLQ
                     DGNWKQAITQLEALDNRYPFGPYSQQVQLDLIYAYYKNADLPLAQAAIDRFMRLNPTH
                     PNIDYVMYMRGLTNMALDDSVLQGFFGVDRSDRDPQHARAAFNDFSKLVRSYPNSQYT
                     TDATKRLVFLKDRLAKYEYSVAEYYTARGAWVAVVNRVEGMLRNYPDTQATRDALPLM
                     ENAYRQMQLNAQADKVAKIIAANSKNT"
     gene            5774..6112
                     /gene="raiA"
                     /locus_tag="OPV72_003455"
     CDS             5774..6112
                     /gene="raiA"
                     /locus_tag="OPV72_003455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HCR9915662.1"
                     /translation="MTMNITSKQMEITPAIRQHVADRLAKLEKWQTHLINPHIILSKE
                     PQGFIADATINTPNGHLVASAKHEDMYTAINELINKLERQLNKVQHKGEARRATASVK
                     DASFVEAEEE"
     misc_feature    6215..6340
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01859"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Phe leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF01859"
     gene            6216..6263
                     /gene="pheL"
                     /locus_tag="OPV72_003456"
     CDS             6216..6263
                     /gene="pheL"
                     /locus_tag="OPV72_003456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_449055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pheA operon leader peptide PheL"
                     /protein_id="HCR9915663.1"
                     /translation="MKLTRFFFAFFFIFP"
     gene            6363..7523
                     /gene="pheA"
                     /locus_tag="OPV72_003457"
     CDS             6363..7523
                     /gene="pheA"
                     /locus_tag="OPV72_003457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional chorismate mutase/prephenate
                     dehydratase"
                     /protein_id="HCR9915664.1"
                     /translation="MTSENPLLALRDKISALDEELLALLAKRRALAIEVGQAKLLSHR
                     PVRDIDRERALLDRLIHLGKAHHLDAHYITRLFQLIIEDSVLTQQALLQQHLNNTHPH
                     SARIAFLGPKGSYSHLAARQYAARHFEQFIESGCAKFTDIFHQVETGQADYAVVPIEN
                     TNSGAINDVYDLLQHTSLSIVGEMTVTIDHCVLVSGATDLNTIETVYSHPQPFQQCSK
                     FLSRYPHWKIDYTESTSAAMEKVAQANSPRVAALGSEAGGMLHGLQVLERIAANQTQN
                     ITRFLVLARKAINVSDQVPAKTTLLIATGQQAGALVEALLVLRNHNLIMTKLESRPIH
                     GNPWEEMFYLDIQANLESQVMQSALKELGEITRSMKVLGCYPSENVVPVEPA"
     gene            complement(7484..8392)
                     /locus_tag="OPV72_003458"
     CDS             complement(7484..8392)
                     /locus_tag="OPV72_003458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMP-30/gluconolactonase/LRE family protein"
                     /protein_id="HCR9915665.1"
                     /translation="MTTPHLLFDYVGHLPECPTWSEDESALYWTDILEQEIYRYHPAS
                     GTHSVLAFPEEVGCFALREQGGFIVAMRHAIWLADKNGLLQRKVCDNPSNTKLARFND
                     GGTDGDGRFYAGTFWAPGDYNGALLMRIDHDLTAKVIQCGIQGHNGLAFSPDNQWMYT
                     SDTPNGVIYRTLLDKHGEPGKRELFRHFGEGEGLPDGAAMDSEGCYWSAMFDGWRVAR
                     FSPQGEQLEEYRLPVRCPTMVCFGGADMKTLFITTTRENMSAQEVADYPLSGAIFTLQ
                     VAVAGMKKSRFIERQAGSTGTTFSLG"
     gene            complement(8450..9571)
                     /gene="tyrA"
                     /locus_tag="OPV72_003459"
     CDS             complement(8450..9571)
                     /gene="tyrA"
                     /locus_tag="OPV72_003459"
                     /EC_number="1.3.1.12"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional chorismate mutase/prephenate
                     dehydrogenase"
                     /protein_id="HCR9915666.1"
                     /translation="MVAELTALRDQIDDVDKALLNLLAKRLELVAKVGEVKSRFGLPI
                     YVPEREASMLASRRAEAEAIGVPPDLIEDVLRRVMRESYSSENDKGFKTLCPSLRPVV
                     IVGGGGQMGRLFEKMLTLSGYQVRILEQQDWPRARDIVADAGMVIVSVPIHVTEQVIA
                     QLPPLPSDCILVDLASVKSGPLQAMLAAHDGPVLGLHPMFGPDSGSLAKQVVVWCDGR
                     QPEAYQWFLEQIQVWGARLHRISAVEHDQNMAFIQALRHFATFAYGLHLAEENVQLEQ
                     LLALSSPIYRLELAMVGRLFAQDPQLYADIIMSSERNLALIKRYYKRFGDAIGLLEQG
                     DKQAFIDSFRKVEHWFGDYARRFQNESRVLLRQANDSRP"
     gene            complement(9581..10651)
                     /gene="aroF"
                     /locus_tag="OPV72_003460"
     CDS             complement(9581..10651)
                     /gene="aroF"
                     /locus_tag="OPV72_003460"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase AroF"
                     /protein_id="HCR9915667.1"
                     /translation="MQKDALNNVRITDEQVLMTPEQLKAAFPLSLAQEAQIAQSRGII
                     SDIIAGRDPRLLVVCGPCSIHDPETALEYARRFKALAAEVSDSLYLVMRVYFEKPRTT
                     VGWKGLINDPHMDGSFDVEAGLKIARQLLVELVNMGLPLATEALDPNSPQYLGDLFSW
                     SAIGARTTESQTHREMASGLSMPVGFKNGTDGSLATAINAMRAAAQPHRFVGINQAGQ
                     VALLQTQGNPHGHVILRGGKAPNYSPADVAQCEKEMEQAGLRPSLMVDCSHGNSNKDY
                     RRQPAVAESVVAQIKDGNRSIIGLMIESNIHEGNQSSEQPRSEMKYGVSVTDACISWE
                     MTDALLREIHKDLSGQLAVRVA"
BASE COUNT         2685 a         3080 c         2598 g         2592 t
ORIGIN      
        1 cagacttctt aacgaagtct tcctgacccg gcggcctgta tgccgttgtt ccgtgtcagt
       61 ggtggcgcat tatagggagt tattagagcc tgacaagacc taaatgcaaa aaaaagctca
      121 accgttcact tttcaaacaa catttgaatc aaaagcctat ttttgcctgg tttttaaaca
      181 aaaacgagcc cgttagggcc cgttttattc aaatttgtga cttactgcac tgccacaata
      241 cgatcatcat tggcttcaag gcgaatcact ttgccaggaa ccagttcacc agacaggatt
      301 tgctgcgcca gtgggttttc gatctgctgt tgaatagcac gttttaacgg acgcgccccg
      361 tagaccggat cgtaaccgtt ggcgctcaac agtttcagcg cctcgtcgga gatatggatt
      421 tcataaccac gttcttccag acgtttgtac agacgctgca gctggatctg agcaatagaa
      481 gcgatgtgtt gctcacctaa cggatggaat accacaactt catcaatacg gttgataaat
      541 tccggacgga agttttggct aaccacaccc agcaccatct ctttcattcg accgtaatcc
      601 agttcgccaa agcgctcctg aatgagatcg gaaccgaggt tagaagtcat aatgaccacc
      661 gtattacgga agtcgaccgt tctcccctgc ccgtcagtca gtcgaccgtc gtccagcacc
      721 tgcaacagaa tgttgaatac atccggatgc gctttttcca cttcatccaa caagatgacg
      781 gaataagggc gacggcgcac cgcttccgtc aaataaccgc cttcttcata gccgacatat
      841 cctggaggcg ccccgaccaa acgagacacg gagtgtttct ccataaactc agacatgtcg
      901 atacgcacca tcgcgtcgtc gctgtcgaac ataaagttag ccagcgcttt acacagttcg
      961 gttttaccga ccccggtcgg cccaaggaac aggaaggaac caatcggacg gttcggatcg
     1021 gacagccccg cgcggctacg gcgtatggcg ttcgatactg cttcaacggc ttcattctgc
     1081 ccgatcacac ggctgtgtaa ctcttgttcc atacgcaaca gtttttcacg ttcgccttcc
     1141 agcattctgg aaaccggaat accggtccag cgcgccagca cttcggcaat ttccgcatcc
     1201 gttactttgt tacgtaacag acgcatggtt ttaccttccg actgggtcgc ggcttccagc
     1261 tgtttttcca gctccggaat tttgccgtac tgcagttcag acattcgcgc gaggtcgcca
     1321 acgcgacgcg cctgctcgat ggcgatcttc gcctgctcca gctccgcttt aatagtttgc
     1381 gtaccagaga gcgacgcttt ttccgctttc cactcttctt ctaactcaga gtactgacgc
     1441 tctttatcgt ccagttcttc attcagcata tcgagacgtt ttttactcgc ctcgtcagac
     1501 tctttcatca acgcctgctg ttccagtttg agctgaataa tgcggcggtc gagcctgtcc
     1561 agctcctccg gcttcgagtc aatctgcata cgaatgctgg atgccgcttc atcgatgagg
     1621 tcgatagctt tatccggtaa ctgacggtcg gcgatatagc ggtgagataa tgttgccgcc
     1681 gccacaatcg ccgggtcagt gatctgcaca tggtgatgca gttcataacg ctctttcaga
     1741 ccacgcaaaa tcgcaatggt gtcttccacc gacggctctg ccacgaacac tttctggaat
     1801 cgacgttcca gcgccgcgtc tttttcgatg tactgacgat attcgtccag cgtggtggcg
     1861 cccacacagt gcagttcccc acgtgccagc gccggtttca gcatgttacc ggcatccatg
     1921 gcgccatcag ctttacctgc gccaaccatg gtgtgcagct cgtcgataaa caggatgacg
     1981 ttgccttcct gttttgcgag gtcgttcagc acgcctttca gacgctcttc aaattcgccg
     2041 cgatatttcg ccccggccac cagcgcgccc atatccagcg ccagcacgcg acggcctttc
     2101 aggccttccg gtacttcacc gttgataata cgttgcgcca gcccttcaac aatggcggtt
     2161 ttacctacgc ctggctcacc gattaacacc gggttgtttt tagtacgacg ttgcaatacc
     2221 tgaatggtac ggcgaatttc ttcatcacga ccaattaccg ggtcaagctt accttgttca
     2281 gcccgctcgg tcagatcgac ggtatatttt ttcaaggcct gacgttggtc ttcagcccct
     2341 tgatcgttca cgctttcacc tccgcgcatc tgttcaattg cctgagtgat attggccgta
     2401 gtcgcaccgg ctgatttcag cagatcggtt aacgtgccgc gagactcaag cgccgccaga
     2461 acaaacagct ctgacgaaat aaaattgtcc ccccgttttt gcgccagctt gtcgcaaagg
     2521 ttcagtacgc gtaccagttc cgaagaaggc tgtacgtcgc cgccggtgcc ttccacctgc
     2581 ggtaaacggc tcagcgcctg atcgatagca gtgcgcaact ggccagcatt aatgccggcg
     2641 gaggttaata aaggacgtat cgatccccct tcctggttca gcaaggcgct cattaaatga
     2701 agaggttcga tgaattggtt gtcgtgcccc agcgcgagcg actgggcatc ggcaagagca
     2761 agctggaatt tgttagtaag acgatccaga cgcataactc ctcccataac aggtcaaaat
     2821 tgctactgga gattaaatga ggtcatccct caattattca aggtgaatga cctgaattat
     2881 gtgaaaagaa agttacccgt accggatcgt cttgattctt taggttatat cagccaaata
     2941 aaacttgcca tacgacctgt cgtcttgtcg cgacgataag agaagaaagt ctcactttcg
     3001 ctaaaggtgc agcgatcccc gccatagaca tgttcaacgc cagtattcgc cagacgttgg
     3061 cgtgcaagct gataaatatc cgccagaaat ttttccccgt gcggcaaaaa tgcgctatcg
     3121 gcttgcgcat cttttgctaa aaatgcgtca cgcacttccg gccccacttc aaacgcggcc
     3181 gggccaatcg ccggacctaa ccaggcgatg atattttctg gtttgtcagc aaagcaggtg
     3241 acagtttcct ccagtacgcc ttcacataat ccgcgccagc ccgcatgagc cgccgccact
     3301 tctgtcccct cacggttaca gaatagcaca ggcaggcagt ctgccgtcat taccgcgcag
     3361 acggttcctg gcgtattgct gtaagacgca tccgcacgtt tggaggcata aggttctccg
     3421 gtaagcctca atacattttt accgtgaacc tgttcaagcc agacaggttt cgaaggcaga
     3481 ttgcccgccg cgaacagacg cttgcggttc tcttcaacat gctccgggtt atcgccgcaa
     3541 tgcgcgccca gattcagcga gtcgtaaggc gataaactca ccccaccaat acgggtagaa
     3601 ctacaggctg cgacgccttt cggcagcggc cactgcggga caatcagtgc attcataacc
     3661 agtccacatc atctttatga tcttcgaaat cggcgcgcat cgcatcgata aggtccacca
     3721 tatcttgtgg aatcggcgcg tgccactcca tttcgatacc cgatacagga tggtagagac
     3781 gcagcatcgt tgcatgcagc gcctggcggt caaacttacg cagcgtggaa ataaattctt
     3841 ccgatgcgcc tttcggtgga cgtggacgac caccgtagac ctgatcgccc actaacggat
     3901 gcgtaatatg cgccatatgc acgcggatct ggtgcgtacg cccggtctcc agacgcaacc
     3961 taagacgcgt gtgcacacgg aaatgttcca taatgcggta gtgggtcacc gccggtttgc
     4021 ccataggatg caccgacata tgggtacgtt tggtcgggtg acgactgatg ggttcattca
     4081 ccgttcctcc cgccgtcata tgtccgatcg cgaccgcttc atattcgcgg gtgatctcgc
     4141 gcagctgcaa agactccacc aggcgcgttt gcgccggaac ggttttggcc accaccatca
     4201 gccccgtcgt gtccttatcc agacgatgca caatgcccgc gcgcgggaca tccgcaatcg
     4261 gcggataata atgtagcaac gcgttcagta ccgtaccgtc cgggttaccc gcgccaggat
     4321 gtaccaccag atcgcgtggt ttgttgataa ccagaatatc gtcatcttca taaacaatat
     4381 ctaacgggat atcctgcgct tcaaaacgaa tctcttcgtc gatctccgca tcaatagcca
     4441 cccgctcgcc gcctaacact ttttcttttg gcttatcgca aagttgacca ttgaccaaca
     4501 cgcgctgatt caaaatccat tcttttatac gcgaacgtga ataatccggg aacatttcgg
     4561 ccaaagcctg atctaagcgt tgaccgagtt ggttttcgga gaccgttgcg gtgagttgta
     4621 ctcgttgtgc catatacagc ttcttcgttt aacgttgggt tttacggctt tgccgtttaa
     4681 tatagtgtgc tattgtagct ggtcttaacc gggagcagga acagagaatc tcccgtaaaa
     4741 cattttgagg aaagtcaaaa cgtcatgacg cgcatgaaat atctggtggc agcagccacg
     4801 ttgagcctgt ttctggcggg ttgctcgggt tcaaaggaag aggtgcccga taatccgccg
     4861 aatgaaatct acgcgactgc tcagcaaaag ctgcaggacg gtaactggaa acaggcaata
     4921 acgcaattgg aagcgttaga taatcgttat ccattcggac cgtattctca gcaggtgcag
     4981 ttggatctta tctacgccta ttacaaaaac gccgatttgc cgctagcgca ggccgccatc
     5041 gatcgtttta tgcgtcttaa tccaacgcac cctaatattg actatgtcat gtacatgcgc
     5101 ggcctgacga acatggcgct ggatgatagc gtgctgcagg gtttctttgg cgtcgatcgc
     5161 agcgatcgcg atccgcaaca tgcgcgggcg gcgttcaatg acttttcgaa actggtacgc
     5221 agctatccta atagccagta caccaccgac gccactaagc gtctggtatt cctgaaagac
     5281 cgtctggcga aatatgaata ttccgtcgca gagtactata ccgcgcgcgg cgcatgggtt
     5341 gcggtcgtaa accgggtaga aggtatgcta cgcaattatc ctgatacgca ggccacgcgc
     5401 gatgcgttgc cgctgatgga aaacgcctat cgtcagatgc agctgaatgc gcaggctgac
     5461 aaagtcgcga aaattattgc cgctaacagc aaaaacacct gaagcaatac caacaagcaa
     5521 aacggcagcc ttccggctgc cgttttttta ttcgatatct gatgcaacag aaatgatttc
     5581 actgcaacgc atccagtcaa atatggcctg ctttcagcca ttcctcaagt aaaagatcgc
     5641 ttcttcctgc gatgcctcac aaaaagttcg ccttgacaaa aagtgacaaa ataatgtgat
     5701 ttacatcaca cattttgaca ttaagaacgg tatgctggaa tcaccaagac gggaaagaca
     5761 agaggtaaaa tttatgacaa tgaacattac cagtaaacaa atggaaatta ctccggcaat
     5821 ccgccaacat gtcgcagacc gtctcgccaa actggaaaaa tggcaaactc acctgattaa
     5881 tcctcatatc attctgtcta aagagccaca gggctttatt gctgacgcca ccattaatac
     5941 accgaacgga catctggtcg ccagcgcaaa acacgaagat atgtacaccg ctattaatga
     6001 attgatcaac aagctggaac ggcagctcaa taaagtgcag cacaaaggcg aagcccgtcg
     6061 tgccaccgca tcggtgaaag atgccagctt cgtcgaagca gaagaagagt agtcccttac
     6121 attgagtgta tcgccaacgc gccttcgggc gcgttttttg ttgacaggat taaaacagta
     6181 cgggtactgt acttacgtac acaaaggaaa cagttatgaa gctcacccgg tttttcttcg
     6241 cattcttttt tatcttcccc tgaccgggag gcgtttcgtc atgtgataaa gaatgcgaag
     6301 acgaacaaga aggcctcccc caccgggagg ccttttttat tgataacaaa aaaggcaaca
     6361 ctatgacatc ggaaaaccca ttactggcgc tgcgagataa aatcagcgct ttagacgaag
     6421 agttactggc cttactggca aaacgacgcg cgctggcgat tgaagtggga caagcaaaac
     6481 tactgtcgca tcgtccggtt cgggatatcg atcgtgaacg cgcgctgctg gacagactca
     6541 tccatctcgg taaagcccac catctcgacg cacactacat tacccgtctg ttccagctta
     6601 tcattgaaga ctccgtgctt actcagcagg cgctgctgca acaacatctg aataatactc
     6661 accctcattc ggcacgtatt gcgtttcttg ggccgaaagg ctcctattct catctcgcgg
     6721 cgcgccagta tgctgcacgc cattttgagc aatttattga gagcggttgc gcaaaattca
     6781 ccgatatttt tcatcaggtc gaaaccggcc aggccgatta cgccgtggtt ccgatagaga
     6841 acaccaactc cggcgctatc aacgatgtgt acgacttatt gcaacacacc agtctgtcga
     6901 ttgtcggtga gatgaccgtc actatcgatc actgcgtgct ggtttccggc gctacggatc
     6961 tgaataccat cgaaacggtg tacagccatc cgcagccgtt tcagcagtgc agtaaatttt
     7021 tgagccgcta tccgcactgg aaaatcgact ataccgagag tacgtcggca gcgatggaaa
     7081 aagtcgcgca ggcaaactct ccgcgcgtcg cggcgctcgg cagcgaggca ggcggcatgt
     7141 tgcacggttt acaggtgctg gaacgcatcg ccgcaaacca gacacagaat atcacccgct
     7201 ttctggtact ggcgcgcaaa gccatcaacg tttccgatca ggttccggca aaaaccactc
     7261 tgttaatcgc caccgggcag caagctggcg cgctggtcga agcgctgctg gtgctgcgta
     7321 accacaatct catcatgacg aaactggagt cgcgccccat tcacggcaat ccgtgggaag
     7381 agatgtttta tctcgatatt caggcgaacc tggagtcgca ggtaatgcaa agcgcgctaa
     7441 aagagctggg cgagatcacg cgctcaatga aagtgcttgg ctgctatccc agcgaaaacg
     7501 tcgtgccggt agaacctgcc tgacgttcaa taaaacggct tttcttcatc cctgcgacgg
     7561 ctacctgcag ggtgaagatg gcgccggaga gcggataatc cgccacttcc tgagcagaca
     7621 tattttctct ggtagttgta ataaacagcg ttttcatatc tgcgccgcca aagcaaacca
     7681 tcgtcggaca acgtaccggc aaccggtact cttccagctg ctctccttgc ggtgagaaac
     7741 gcgccacgcg ccagccgtca aacatcgcgc tccagtagca cccttcgcta tccatcgccg
     7801 cgccgtcggg aagtccttct ccttcgccaa aatggcgaaa aagttcacgc ttgcccggtt
     7861 cgccatgctt atcaagtaac gtgcggtata tcacgccatt cggcgtatcg gaagtataca
     7921 tccactggtt gtccgggctg aacgccaggc cgttgtgtcc ctggataccg cactggatca
     7981 cttttgccgt caggtcatga tcgatccgca tcagcaacgc gccattatag tcacccggcg
     8041 cccagaacgt tccggcataa aaacggccat cgccatcagt gccgccatcg ttgaaacgcg
     8101 ccagtttcgt attagaggga ttgtcgcaaa ccttacgctg caataatcca tttttatcgg
     8161 ccagccaaat agcatgacgc atggccacaa taaatccgcc ctgctcacgc aaggcaaaac
     8221 agcctacctc ttccggaaac gccagcacgc tatgcgtccc actcgccgga tggtaacgat
     8281 agatctcctg ttccaggata tcagtccaat acagcgcgct ttcatcctcg ctccatgtgg
     8341 ggcattctgg taaatgtccg acataatcaa ataaaaggtg cggcgtagtc ataacggttc
     8401 cttaaacgaa aaaagccagc aaagctggct tttagtatag atgtcatcat tatggtcggc
     8461 tgtcattcgc ctgacgtaat aacacacggc tttcattctg gaagcgtctg gcataatcgc
     8521 caaaccagtg ttcaactttg cgaaaactgt cgataaaagc ctgcttatca ccctgttcca
     8581 gtaacccgat cgcatcgcca aaacgtttat agtaacgctt gataagcgcc agattgcgct
     8641 ccgacgacat aataatgtct gcatacagct gcgggtcctg ggcgaacaga cgcccgacca
     8701 tcgccagctc cagtcgataa atcggcgatg atagcgccag aagctgctca agctggacgt
     8761 tctcttccgc cagatgcagc ccataagcga aggtagcaaa gtggcgcagc gcctggataa
     8821 aagccatgtt ctgatcgtgc tcgacagcgc taattcggtg caaccgcgcg ccccacacct
     8881 ggatttgctc aaggaaccac tgatacgctt ccggttgacg cccatcacac cagaccacca
     8941 cctgcttcgc caggctcccg ctgtccgggc caaacatcgg gtgcaagccc agcacggggc
     9001 catcatgggc cgccaacatt gcctgtaacg gaccgctttt caccgatgcc agatcgacca
     9061 gaatacagtc ggacggcagg ggcggcagtt gcgctatgac ctgttcagta acatgaatcg
     9121 gcacgctgac gatcaccatt ccggcatcgg cgacaatgtc cctggcgcgc ggccagtcct
     9181 gttgttccag aatacggacc tgatagcccg acagcgtgag cattttttca aacagacgcc
     9241 ccatctgtcc gccgccgccc acaatgacga ccggacgcag agaaggacaa agcgttttga
     9301 accccttatc attttcgctg gagtaagatt cacgcattac ccggcgcagg acatcttcaa
     9361 tgagatcggg cgggacaccg atcgcttctg cttccgcccg tcgtgaagcc agcatagagg
     9421 cctcacgctc cggcacgtaa ataggcaggc caaaacggct tttcacctcg ccgactttgg
     9481 caaccagttc caggcgctta gccagtaaat tcaacaacgc tttatcgaca tcatctattt
     9541 gatcgcgtaa cgcggtcaat tcagcaacca taacaacctc ttatgcgacg cgcaccgcca
     9601 gctggccgct caaatcttta tgaatttcac gtaacagggc atcggtcatc tcccagctaa
     9661 tacaagcatc ggtgacggaa acgccatact tcatttcgct gcgcggctgt tcggaagact
     9721 gattaccctc atgaatatta ctttcaatca ttaagccaat gattgaacga ttgccatctt
     9781 taatctgcgc aaccacagat tcggcaacgg ctggctggcg gcgataatct ttattggagt
     9841 taccatgact gcaatctacc atcagcgaag gacgtagccc cgcctgttcc atctcttttt
     9901 cacactgagc gacatctgcc gggctatagt ttggcgcttt gccgccacgc agaatcacat
     9961 ggccatgcgg atttccctgg gtttgcaata acgcaacctg accggcctgg ttaatgccaa
    10021 caaaacgatg aggttgcgca gcggcgcgca tggcgttaat cgctgtcgcc aggctgccat
    10081 ccgtgccgtt tttaaagccg accggcatag aaagaccaga cgccatttcg cggtgggttt
    10141 gcgattcggt tgtgcgcgcg cctatcgccg accagctaaa cagatcgccc aggtattgcg
    10201 ggctgttcgg atccaacgct tcggtcgcca atggcaaccc catattcacc agttccacca
    10261 gtagctgacg cgctattttc aacccggctt ccacatcaaa tgagccatcc atgtgaggat
    10321 cgttaatcag ccctttccag ccgacggtag tccgcggctt ttcaaaatag acgcgcatta
    10381 ccagatagag gctatcgctg acctctgcgg caagggcttt aaatcgacgg gcatattcca
    10441 gagcggtttc aggatcgtga atagaacaag gaccgcatac caccaacaga cgcggatcgc
    10501 gcccggcaat aatgtcagaa atgattcccc gggactgcgc tatctgcgct tcctgcgcca
    10561 ggctcaacgg aaaggccgct ttaagctgct ccggcgtcat taatacctgt tcatcggtga
    10621 tacgtacgtt attcagcgcg tctttttgca tgatggcgat cctgtctttt cttgtttgcg
    10681 atagttgatc ctccacgagg atgtttaaac cataccacaa aaagtaaaga tttcaatcca
    10741 tattacgtaa aataaacttt acatagtgct aaatcgtcga ttaaacctct caatttcgta
    10801 tcaaaaactt tacacaacaa gtgaattatt ttattcccag cttcagaaaa gcggtaaaat
    10861 gagcgatgct cgctattttt tgattatttt ttctccgcac gcataatttt actttctgat
    10921 atagggtgat taataccatt atcacaagaa tttaa
//
LOCUS       DAJVBX010000162        10906 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.162, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000162 DAJVBX010000000
VERSION     DAJVBX010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 10906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10906
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.162"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(11..730)
                     /locus_tag="OPV72_003461"
     CDS             complement(11..730)
                     /locus_tag="OPV72_003461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2884 domain-containing protein"
                     /protein_id="HCR9915668.1"
                     /translation="MMRKTLLAAVLTFTAMAAHADYKCSVTPRDDVILSPQTVQVKGE
                     NGNLVITPDGNVMYNGKQYTLSAAQREQAKDYQAELRSALPWIDEGARSRVEKGRVAL
                     DKIIAKEVGESSNMRSRLTKLDAQLKAQMNRIIEHRTDGLTFHYKAIDQVRADGQQLV
                     NQAMGGILQDSINEMGAKAVLKGGGNPLQGVMGSLGGLQTAIQNEWKNQEKDFQQFGK
                     DVCSRVVTLEDSRKALVGSLK"
     gene            complement(780..1106)
                     /locus_tag="OPV72_003462"
     CDS             complement(780..1106)
                     /locus_tag="OPV72_003462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggL family protein"
                     /protein_id="HCR9915669.1"
                     /translation="MAKNRSRRLRKKMHIDEFQELGFSVAWRFPEGTSEEQIDKTVDD
                     FINDVIEPNKLAFDGSGYLAWEGLICMQEIGKCTEEHQAIVRKWLEARNLEEVRTSEL
                     FDVWWD"
     gene            complement(1106..1825)
                     /gene="trmB"
                     /locus_tag="OPV72_003463"
     CDS             complement(1106..1825)
                     /gene="trmB"
                     /locus_tag="OPV72_003463"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HCR9915670.1"
                     /translation="MKNDVISPEFDENGRPLRRIRSFVRRQGRLTKGQEHALENYWPV
                     MGVEFSEAPVDFATLFGREAPVTLEIGFGMGASLVAMAKARPEQNFLGIEVHSPGVGA
                     CLASAHEEGVENLHVMCHDAVEVLHKMIPDNSLSMVQLFFPDPWHKARHNKRRIVQVP
                     FAELVLSKLKLGGVFHMATDWEAYAEHMLEVMSSIDGYKNLSESNDYVPRPESRPVTK
                     FEQRGHRLGHGVWDLMFERVK"
     gene            1980..3032
                     /gene="mutY"
                     /locus_tag="OPV72_003464"
     CDS             1980..3032
                     /gene="mutY"
                     /locus_tag="OPV72_003464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HCR9915671.1"
                     /translation="MQASQFSAQVLDWYDKYGRKTLPWQINKTPYKVWLSEVMLQQTQ
                     VTTVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGG
                     EFPQTFAEIAALPGVGRSTAGAILSLALGKHYPILDGNVKRVLARCYAVSGWPGKKEV
                     ENTLWTLSEQVTPARGVERFNQAMMDLGAMVCTRSKPKCTLCPLQNGCIAAAHESWSR
                     YPGKKPKQTLPERTGYFLLLQHNQEIFLAQRPPSGLWGGLYCFPQFASEDELREWLAQ
                     RHVNADNLTQLNAFRHTFSHFHLDIVPMWLPVSSLDACMDEGGALWYNLAQPPSVGLA
                     APVERLLQQLRTGAPV"
     gene            3060..3335
                     /locus_tag="OPV72_003465"
     CDS             3060..3335
                     /locus_tag="OPV72_003465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidative damage protection protein"
                     /protein_id="HCR9915672.1"
                     /translation="MSRTIFCTYLQRDAEGQDFQLYPGELGKRIYNEISKDAWAQWQH
                     KQTMLINEKKLNMMNAEHRKLLEQEMVSFLFEGKDVHIEGYTPEDKK"
     gene            3448..4533
                     /gene="mltC"
                     /locus_tag="OPV72_003466"
     CDS             3448..4533
                     /gene="mltC"
                     /locus_tag="OPV72_003466"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane-bound lytic murein transglycosylase
                     MltC"
                     /protein_id="HCR9915673.1"
                     /translation="MMKKLLALAVIAPLLISCSSSTKKGETYNEAWVKDTNGFDILMG
                     QFANNIENLWGYKEVLIAGPKDYVKYTDQFQTRSHINFDDGTITVETIAGTEPTAHLR
                     RAIIKTLLMGDDPTSVDLYSDVDDIKISKEPFLYGQVLDNTGQPIRWEGRATTFADYL
                     LKTRLKSRSNGLRIIYSVTINLVPNHLDKRAHKYIGMVRQASRKYGVDESLILAIMQT
                     ESSFNPYAVSHADALGLMQVVQHSAGKDVFRSQGKSGTPSRNFLFDPASNIDTGTAYL
                     AMLNNVYLSGIENPTSRRYAVITAYNGGAGSVLRIFSNDKIQAANMINRMSPGDVYQI
                     LTTRHPSAESRRYLYKVNSAQRSYRRR"
     gene            4750..6006
                     /locus_tag="OPV72_003467"
     CDS             4750..6006
                     /locus_tag="OPV72_003467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside permease"
                     /protein_id="HCR9915674.1"
                     /translation="MNLKLQLKILSFLQFCLWGSWLTTLGSYMFVTLKFDGASIGAVY
                     SSLGIAAVFMPTLLGIVADKWLSAKWVYALCHVVGAITLFMAAEVTTPGAMFFVILLN
                     SLAYMPTLGLINTISYYRLQSAGMDIVTDFPPIRIWGTIGFILAMWGVSFSGFELSHM
                     QLYIGATLSVLLVLFTFTLPHIPVANQQKNQSWTSMLGLDAFALFKNKRMAIFFIFSM
                     MLGAELQITNMFGNTFLHSFDKDPLFASSFIVQHASVMMSISQISETLFILTIPFFLS
                     RYGIKNVMLISIVAWMLRFGLFAYGDPTPFGTVLLVLPMIVYGCAFDFFNISGSVFVE
                     KEVRPEIRASAQGMFLMMTNGFGCILGGIVSGKVVEYYTQNGITDWQTVWLIFAGYSL
                     VLAFAFVALFKYKHVRVPASSQPVAH"
     gene            complement(6068..8192)
                     /locus_tag="OPV72_003468"
                     /pseudo
     CDS             complement(6068..8192)
                     /locus_tag="OPV72_003468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462030.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine decarboxylase"
     gene            8617..9324
                     /locus_tag="OPV72_003469"
     CDS             8617..9324
                     /locus_tag="OPV72_003469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HCR9915675.1"
                     /translation="MVIGPFINAGAILFGGVIGALLSQRLPERIRVSMTSIFGLCSLG
                     IGILLVMKCANLPVMVLATLVGALIGEFCLLEKGINGAVAKIQQLFMASGKKPTHDSF
                     IQSYVAIIVLFCASGTGIFGAMHEGMTGDPNILIAKSFLDFFTAIIFACSLGIAVSAI
                     CAPMLIIQLTLAACATLILPLTTPAMMGDFSAVGGLLLVATGLRVCGIKMFPVVNMLP
                     ALLLAMPISAAWAMFFA"
     gene            9430..9505
                     /locus_tag="OPV72_003470"
     tRNA            9430..9505
                     /locus_tag="OPV72_003470"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9463..9465,aa:Phe,seq:gaa)
     gene            9666..10479
                     /locus_tag="OPV72_003471"
                     /pseudo
     CDS             9666..10479
                     /locus_tag="OPV72_003471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009114529.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase arm-type DNA-binding domain-containing
                     protein"
BASE COUNT         2568 a         2936 c         2729 g         2673 t
ORIGIN      
        1 aaaggaaaga ttacttcagg ctgccaacca gcgctttgcg gctatcttct aaggtcacta
       61 cgcggctaca gacatctttg ccaaactgct ggaaatcttt ctcctggttt ttccattcgt
      121 tctggatagc ggtttgcaaa ccaccgagac tacccatcac gccctgtaaa ggattgccgc
      181 cgcctttaag caccgctttg gcgcccattt cgttaatgct gtcctgcaaa ataccgccca
      241 tcgcctgatt caccaactgc tgaccgtcgg cacgcacctg gtcgatagcc ttatagtgga
      301 acgtcaggcc gtccgtacga tgttcgataa tgcggttcat ttgcgctttt aattgcgcat
      361 caagcttcgt caggcggctg cgcatgttgc tgctttcgcc cacctcttta gcgatgattt
      421 tatccagcgc cacgcggcct ttttcgacgc gcgatcgggc gccctcatca atccacggca
      481 gcgcgcttcg cagttccgcc tggtaatctt tcgcctgctc gcgctgcgcg gcgctaaggg
      541 tgtactgctt accgttgtac atcacattgc cgtccggcgt gatcaccagg ttgccgtttt
      601 cacctttcac ctgcaccgtt tgtggactca ggatcacatc gtcacgcggc gtgacgctgc
      661 atttgtaatc tgcatgagcg gccatcgccg taaacgttag cactgccgcc agcagcgttt
      721 tgcgcatcat aactttccct caagacaaag cgggccggca tttgccgacc ctgtacttat
      781 tagtcccacc aaacgtcgaa aagttcgctg gttcggactt cttcaaggtt gcgcgcttcc
      841 agccacttac gcacaatcgc ctgatgttct tcggtacatt taccgatttc ctgcatacaa
      901 atcagccctt cccaggccag gtagccgctg ccgtcaaacg ccagtttatt aggctcaata
      961 acgtcattaa taaagtcatc gacagtctta tcgatctgct cttcagatgt accttccgga
     1021 aaacgccatg ccaccgaaaa tcctaattcc tggaattcgt caatgtgcat ttttttacgc
     1081 agacgacgac tacggttctt tgccattatt tcaccctctc gaacattaag tcccatacgc
     1141 catgaccaag acgatggcca cgttgttcaa atttcgttac cgggcgcgat tccgggcgcg
     1201 gtacataatc attgctctct gacagatttt tgtacccgtc gatagaagac atgacttcaa
     1261 gcatgtgttc cgcatacgct tcccagtcgg tcgccatatg gaaaacgccg cccaatttca
     1321 gcttgctcaa taccagttca gcaaacggca cctgaacgat acggcgttta ttatgacgcg
     1381 ctttatgcca cgggtcaggg aaaaagagct gaaccatcga taaagaattg tcaggaatca
     1441 ttttatgcaa cacttctacc gcgtcgtggc acatgacgtg caggttttca acgccctctt
     1501 catgagcgga cgccagacac gcgccgacac cgggtgaatg cacttcaatg ccgaggaaat
     1561 tctgctccgg gcgcgctttc gccatcgcca cgagagacgc ccccatgcca aaaccaatct
     1621 ccagcgtcac cggcgcttcg cgaccaaaca acgtggcgaa atctaccggc gcttcgctga
     1681 actcgacgcc catcaccggc cagtagtttt ccagcgcgtg ctcttgcccc tttgtcagtc
     1741 gcccctggcg acgaacaaaa ctacgaatac ggcgcagcgg gcgaccgttt tcatcaaatt
     1801 ccggtgaaat gacgtcgttt ttcataaaag tgtagtctgc tgtgtttgag ttctgaaaac
     1861 gggcattatc caaagttagt tgccggatgc aagcatgaag cgcactgcgg aaagttccgg
     1921 tttacaccct gcggcctctg tgctgcaatc ttgcccccgg caataatgaa tgagtttcca
     1981 tgcaagcgtc tcaattttca gcccaggttc tggactggta cgacaaatac gggcggaaaa
     2041 cgctgccctg gcaaattaac aagacgcctt acaaagtatg gctctcggaa gtcatgttgc
     2101 aacaaacgca ggtgacgacg gtgattcctt actttgagcg atttatggcg cgctttccga
     2161 cggtaacgga tttagcgaat gcgccgctgg atgaagtgct ccatttatgg accgggctcg
     2221 gctattacgc ccgcgcgcgt aatttgcata aagcggcgca acaggtagca acgcttcacg
     2281 gtggagaatt cccgcaaact tttgccgaaa tcgccgcgct ccccggcgtc gggcgttcaa
     2341 ccgccggcgc gattctctcc ctcgcgttag gtaaacatta tccgattctt gatggaaacg
     2401 ttaaacgtgt gctggctcgc tgttatgctg ttagcggctg gcctggaaaa aaagaggtgg
     2461 agaatacgct gtggacgctg agcgagcaag tgacgcccgc acgcggcgtg gagcgtttta
     2521 atcaggcgat gatggatctg ggcgcgatgg tttgtacgcg ttcaaagcca aagtgcaccc
     2581 tgtgtccgct gcaaaacggt tgtatcgccg ctgcgcatga aagctggtca cgctatccgg
     2641 gcaagaaacc gaaacagacg ttgccggagc ggacgggtta ctttttattg ttacagcata
     2701 atcaggagat tttcctggcg cagcgccctc ccagcggttt atggggcgga ctctactgct
     2761 ttccgcagtt cgccagcgaa gatgaattac gtgaatggct ggcgcaacgg catgttaacg
     2821 ctgataattt gacccagctt aacgcgtttc gccacacatt tagccatttc cacctggata
     2881 ttgtgcctat gtggcttccc gtgtcgtcac tggacgcctg catggatgaa ggcggcgcgc
     2941 tctggtataa cttagcgcaa ccgccgtcag tcggactggc ggcccccgtg gagcgcttgt
     3001 tacagcagtt acgtaccgga gcgccagttt aacgccccgg tcgatgaaga ggatgactta
     3061 tgagcagaac gattttttgt acttacctgc aacgcgacgc tgaagggcaa gattttcagc
     3121 tctaccctgg cgaactagga aaacgtatct ataacgagat ctctaaggac gcgtgggcgc
     3181 agtggcagca taagcagacc atgttgatta acgagaaaaa gctcaacatg atgaacgccg
     3241 agcaccgtaa actgctggaa caggagatgg tgagcttcct gttcgaaggc aaagacgttc
     3301 atatcgaagg ttatacgccg gaagataaaa aataggcccg ttgctgaatg aggctgcgct
     3361 tattcggcct gtgagttatg ccggataagc ccttagcgcc gctgcccggc aacatggcat
     3421 aacgacaaca caacatgcac tcccggaatg atgaaaaaat tactcgcgct tgctgttatt
     3481 gcgccgttgc tcatctcctg ctccagttcg accaaaaaag gcgagacgta taatgaagcc
     3541 tgggtcaagg ataccaacgg ctttgatatt ttgatggggc aatttgccaa caatattgaa
     3601 aatctgtggg gatataagga agtcctgatc gccgggccga aagactacgt caaatatacc
     3661 gatcagttcc agacccgtag ccacatcaac tttgatgatg ggaccattac cgttgaaacc
     3721 atcgccggga cggaacctac cgcacatctg cgccgggcca ttattaaaac gttgctcatg
     3781 ggtgacgacc caacctccgt cgatctttac tccgatgtcg atgacataaa aatttctaaa
     3841 gaacccttcc tgtatggtca ggtcctcgac aataccggcc agcctattcg ctgggaaggc
     3901 cgcgccacga cattcgcgga ttacttgctg aaaacgcggc tcaaaagccg cagtaacggc
     3961 ctgcgtatta tttacagcgt caccattaat ctggtgccga accaccttga taaacgcgcg
     4021 cataaataca ttggcatggt acgccaggcc tcccgtaaat acggcgttga cgagtcgctg
     4081 attctggcga ttatgcaaac ggagtcctcg tttaacccgt atgcggtcag ccacgcggat
     4141 gcgctgggcc tgatgcaggt agtgcaacac agcgccggga aagatgtttt ccgttctcag
     4201 ggtaagtccg gcacgccaag ccgtaacttc ctgttcgacc ccgccagcaa tatcgatacc
     4261 ggcacagcgt atctggcgat gttgaataat gtctatctga gcggtatcga gaatccgacg
     4321 tcgcggcgct atgcggtcat tactgcctat aatggcggcg caggcagcgt attacgcata
     4381 ttctcgaacg ataagattca ggccgcgaat atgattaacc gcatgtcgcc gggggatgtg
     4441 taccagatat taaccacccg acatccatct gcggagtcgc gccgctatct gtataaggtg
     4501 aattccgccc agcgatcgta tcgccgccga taaaccatcg catcccgcct ctggccagca
     4561 aatgacagag gcgggaaagg caaaagtgtt aactccgtca cccttttgct ttgcaatcag
     4621 aaattgtttg caaatatttg tcacaggtaa caaaaaaagc ccgcctctca ttgatagaat
     4681 cacaccaaat cacaacggca aatgtgcctt ttaaaacatt catccgctct caggtgtgag
     4741 gaaattaaca tgaatcttaa gctgcagctt aaaatactct cttttctgca gttctgtctg
     4801 tggggaagct ggctcactac cctgggctcg tatatgttcg tcaccttaaa atttgacggc
     4861 gcatctattg gcgcagttta tagttcactg gggattgctg ccgtctttat gccgaccttg
     4921 ctaggcattg tggctgacaa atggctgagc gcgaaatggg tctatgccct gtgtcatgtc
     4981 gtcggcgcca tcacgctatt catggccgcg gaagtcacta cgcctggggc gatgttcttt
     5041 gtgatcctgc ttaactcgtt ggcttatatg ccgacgttgg gcttgatcaa tactatatcg
     5101 tattaccgcc tgcagtctgc cggcatggat attgtgactg actttccgcc tatccgtatc
     5161 tggggcacca tcggctttat tctggcgatg tggggcgtga gtttctccgg tttcgagctg
     5221 agccatatgc agctttatat cggcgcgacg ctttccgttc tgctggtact gtttaccttt
     5281 accctgccgc acattccggt ggcgaaccaa cagaaaaacc agagctggac atcaatgctg
     5341 ggccttgacg cttttgcgct gtttaaaaac aagcggatgg cgattttctt catcttctcc
     5401 atgatgctgg gcgcggaact gcagatcacc aacatgtttg gcaacacctt cctgcatagc
     5461 tttgataaag atccgctatt cgccagtagc tttatcgtgc agcacgcctc ggtgatgatg
     5521 tcgatttcgc agatttctga aacgttattc atcctgacca ttccgttctt cctgagccgt
     5581 tatggtatta agaacgttat gcttatcagt attgtggcgt ggatgctgcg tttcggcctg
     5641 ttcgcttatg gcgacccgac gccgttcggt accgttctgc tggtattgcc gatgattgtg
     5701 tacggctgcg ccttcgactt cttcaacatt tctggctcgg tgtttgtcga aaaagaagta
     5761 cgcccggaaa tccgcgccag cgcgcagggg atgttcctga tgatgaccaa tggcttcggc
     5821 tgtatccttg gcggcattgt gagcggtaaa gtggtggagt attacactca aaacggcatt
     5881 accgactggc agaccgtgtg gctcatcttc gcaggctact cgctggtgct ggcctttgcg
     5941 ttcgtagcct tgttcaaata caaacacgtt cgcgttccgg caagttcgca acccgttgca
     6001 cattaatcct tgccctgttt cgcaggccgg ataaggcgta aatgccttat ccggcctgca
     6061 ggcaacgtta ctttaaaaca tatccataca agcgtttaat tccatcggca tcggtctcgc
     6121 tatatacccc ctgcaattcc ggcgaaaaac cgagcaacag attgatgccc tcttccagcg
     6181 ccaaaaaata acgctgcgcc gcgccacccc aaatctcccc cggcaccacg cacagtacgc
     6241 ccggcgggta tggcaatgcc ccctcggcag caatacgccc gcccgcctcg ctgatacgca
     6301 ccagctctac atcgccgcga ataaaggcgc tgttggcatc ctgcgggttc atcgccacat
     6361 gcggcaggct ttctttgcga aacatcgctt tttgcagatc cttaacgtca aagctaacgt
     6421 acaggttgtg catctcctga catagctcac gcagggtgta atcgcggtag cgcaccgggt
     6481 atttctgaaa aaccgtcggc aatacatccg caagcggcgt atcgtcttca atgtgccgtt
     6541 caaattgcgc cagcatcgcg accagtcgcg ccagtttctc ttcgctctcg gcgggtgtca
     6601 gcaagaatag aatcgagttg agatcgcact tctcaggcac aataccgttc tcacgcagat
     6661 agtgggcgag aatggtcgcc gggatgccga attcggtgta ccgcccacta tcggcatcaa
     6721 tacctggcgt ggtcagtaac agtttacaag gatcgacaaa atactggtca tccgcataac
     6781 cctcaaagcc atgccatttc gccccgggct caaaactgaa gaaacgacga ttgctggcaa
     6841 tggtctccgt cggatatgcc tgccacggct tgccgtcaac caccagtggg ataaagggct
     6901 gaagcagttt gcaacgggcg agaatggctt tacgcgcgtc aatgcccagc gcaacgcact
     6961 ccgcccacag gcggcgaccg ctctcccctt cgtggatttt ggcattgaca tccagcgccg
     7021 caaacagcgg gtagaacgga ctggttgaag catgcaacat gaaggcgttt gtgcgggcaa
     7081 aaacgcgcct ggccgcgaat atggttatct tttttgtgga tctgcgaggt ttgtgagaac
     7141 cccgcctgtt gcttatgtac cgattgggtc acaaagatcc cagggtcgtt ttcattaagc
     7201 tccagccgca acggcgaggt atccgccatc atattgataa actgctcata gcctacccac
     7261 gcggagtcaa acagaatgta atcgcagaga tgcccgattt tatccaccac ctgacgggcg
     7321 ttgtaaatag tgccgtcata ggtacccagc tgaatgatcg ccaggcggaa cggacgcggc
     7381 gcatcggcgc tttccggcat cacgtcacga atctggtcgc gcaggtacgt ttcatcaaaa
     7441 cagtgcgcat caataccacc gataaaacca aacgggttac gcgccgcctc aagatagacc
     7501 ggcgtcgccc cggcctgaat cagggcgccg tggtggttgg atttgtgatt atttcgatca
     7561 aacagcacca gatcgccgcg cgtcagcaag gcgttggtga ccactttatt cgccgccgaa
     7621 gttccattca gcacaaagta ggttttatcc gcattaaaca cttttgccgc aaatttctgc
     7681 gcgtgtttgg cagaaccttc atgtattagc agatcgccaa gtttcacatc ggcgttacac
     7741 atatccgcac gaaacaggtt ttcaccaaaa aagtcataaa aatggcggcc tgcgggatgt
     7801 tttctaaaaa actcgccatg ctggtgcccc gggcaagcaa aggtactatt ccccatgtcg
     7861 acatactggg tcagggtgcc ataaaagggc ggcagaagtt ccgcttcgta gcgacaggca
     7921 gcgttttcca gctccagcca ttcctgcgcg ttcccgccga ttaccgccgt aacgccgaca
     7981 ggcgcgctga cgggttcatc cgcaagcata aataccggca ggtgaaaacc ggtgcgttta
     8041 agcaacgcca gaataccgct acggctgtcg gcagtggtaa tgacgactgc ggccacatcg
     8101 gtaaagtcgg tactttccag tgccactacg tttcggtggg tggagagacg ggggatgagt
     8161 tcaccgctgg cggcaatatt cattgatttc ataagcgcaa atacccgttt cgggagtaga
     8221 gtaaccccgg acaaggccga tgccttgccc aacgagatgc cgggtcaaac tggataccag
     8281 ctccgaccgc cagacatcag taaaaacaga ctgtttctga ttttactgtt gtcctgcagt
     8341 gagcgtgcgc tgccctcacc gcatagcggg gatgacaaaa aaaaggaaag aaaggggcaa
     8401 acctcgcgca gtcaggcgac agtgaagaca atataaaggc gctatgttca tcccggcgag
     8461 ccccatgctg gcaggagaaa tttcgcgcaa tcatggcacc tttcaccaga cggcgcaagg
     8521 taaaatcagc gctctatacg tcacagataa tcaagctatt aacagcttaa tcgcgtgata
     8581 ataaggcaat ttgaaagaca aataacagga gtcattgtgg taattggacc ttttattaac
     8641 gctggcgcaa ttttattcgg cggcgttatt ggcgcgctgt taagtcagcg tctgccagaa
     8701 cggattcgcg tctcaatgac gtctattttt ggtctgtgct ctctgggtat tggcattctg
     8761 ctggtgatga agtgcgctaa tcttccggtg atggtgctgg cgacgctggt cggcgcgctt
     8821 atcggcgagt tttgtttgct ggaaaaaggc attaatggcg cagtcgcgaa aatccaacaa
     8881 ttatttatgg catcgggtaa gaagccgaca cacgactctt ttattcaaag ttacgtcgct
     8941 atcattgtac ttttttgcgc cagcggcacc ggtattttcg gcgcgatgca tgaagggatg
     9001 accggcgatc caaacatttt gatcgctaaa tcttttctgg atttttttac tgccattatt
     9061 ttcgcctgtt cgcttggcat cgccgtttcg gcgatttgcg caccgatgtt gattatccag
     9121 ttaacgcttg ccgcctgcgc caccctcatt cttccactga ctacgccggc aatgatgggc
     9181 gactttagcg ccgtgggcgg gctgctgctg gtggcaaccg gcttgcgtgt atgtggaatc
     9241 aaaatgtttc cggtagtgaa tatgctcccg gcgctgttgc tggcgatgcc gatctccgcc
     9301 gcatgggcga tgttttttgc ctgactctgc gtgcaataac aacaaagtgg tgatagattg
     9361 tgcagtctac gttgatttga agaaatttcg ttgacgaagc gaggcgatta cggtttaatg
     9421 cgcctcgttg cccggatagc tcagtcggta gagcagggga ttgaaaatcc ccgtgtcctt
     9481 ggttcgattc cgagtccggg caccaccttt ccttttttac acttccttat aaatccccat
     9541 gtgtttttaa ttcaatgagt tagtggaaaa actcttccca gcgaatttct atttatccgc
     9601 ccaaatcagg ggcttttggt ggtcaactcg gtgctcagtt cggttagata aaggagtgcc
     9661 ctcaaatggc attaaccgac aaacaagcac gtagtgcaaa gccttctgat aaaccctata
     9721 aactcgttga tacactcggc ctgtatcttc tggtaaaacc caacgatttt cgtatctggt
     9781 atttcaaata tcgttttgag ggaaaagagt ccggggtatc attcggtcct tatcccgaaa
     9841 cctcattcgc ccttgtccgc gaaaaacgcg atgccacccg gcgcgtacta aaatccggct
     9901 ttaccccttc tcagcagcgc cgggacgaaa aaaggttgtc aatgaattag aacgttccag
     9961 tacatcgcta gattgtggca taccggctgc ctgaaactct ggtcagaaag tcactccaat
    10021 aaaattcctg tctgcctcca acactacgtt ttccctgata tcggcgcaat gggtatttcg
    10081 gcgacttaaa ccctacatct cgcacgactg gtcagagaca ttgatgataa aggtgtgcat
    10141 gttgttgccg gacgtatacg ccagcatctg accaaaatta tgcgccacgc cgtacagcag
    10201 ggaacgatta aatataatcc ggcattcgat ctggatggcg ttgtaactcc tgttataacc
    10261 cagcatcacc ccgcccttcc cctgaaacgc ctgcctgaat tgctgggcta tatcgacacc
    10321 tacaacaagg ccggataccg gctatcaaca ctttccggta tgccgcactg ccaggacaac
    10381 accaaacgtg agttcacaca tctggttaga gtttctctgg cttaccgcaa aattgagtgg
    10441 gaacacgttt caacaggcac ttcaggtgct gatgactgac gtgcgccgct ggaagcataa
    10501 gagtaaatcc acagcattcc gccttaatgg tgggatgctg tttttgtccg ggaacggaga
    10561 caaaaagccc gtgccagcaa tgagttacgt ctgttacgtt tcatatatgg gagatggtgg
    10621 atgccggaaa ctttggcggt agcgtgcctg aagcggctgt cctccccatt gccactgcca
    10681 cgagcgtacc gtggttcctt tttcgccaat aaatccagaa taaggttatg tcacaaaatg
    10741 gcctgcgttt tacgctggat gtggacggat taacgccggc ggcaaccact gtcgtcagct
    10801 tcaccctcca gaggtatcaa cagttcaaca ggtgcaagct ggaataagaa tgaaagacta
    10861 aaaacaccag atgatgcatc caatgatagc attaaatcag gccatg
//
LOCUS       DAJVBX010000163        10885 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.163, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000163 DAJVBX010000000
VERSION     DAJVBX010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 10885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10885
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.163"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            115..1035
                     /gene="oppB"
                     /locus_tag="OPV72_003472"
     CDS             115..1035
                     /gene="oppB"
                     /locus_tag="OPV72_003472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease OppB"
                     /protein_id="HCR9915676.1"
                     /translation="MLKFILRRCLEAIPTLFILITISFFMMRLAPGSPFTGERALPPE
                     VLANIEAKYHLNDPIMTQYFSYLKQLAHGDFGPSFKYKDYTVNDLVAASFPVSAKLGA
                     AAFLLAVIIGVSAGVIAALKQNTRWDYTVMGFAMTGVVIPSFVVAPLLVMVFAITLQW
                     LLGGGWNGGALKFMILPMVALSLAYIASIARITRGSMIEVLHSNFIRTARAKGLPMRR
                     IIFRHALKPALLPVLSYMGPAFVGIITGSMVIETIYGLPGIGQLFVNGALNRDYSLVL
                     SLTILVGALTILFNAIVDVLYAVIDPKIRY"
     gene            1050..1957
                     /gene="oppC"
                     /locus_tag="OPV72_003473"
                     /pseudo
     CDS             1050..1957
                     /gene="oppC"
                     /locus_tag="OPV72_003473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000979653.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease OppC"
     gene            1969..2976
                     /locus_tag="OPV72_003474"
     CDS             1969..2976
                     /locus_tag="OPV72_003474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR9915677.1"
                     /translation="MSLSETATQAPQPANVLLEVNDLRVTFATPDGDVTAVNDLNFTL
                     RAGETLGIVGESGSGKSQTAFALMGLLATNGRIGGSATFNGREILNLPERELNTLRAE
                     QISMIFQDPMTSLNPYMRVGEQLMEVLMLHKGMSKAEAFEESVRMLDAVKIPEARKRM
                     KMYPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNT
                     AIIMITHDLGVVAGICDKVLVMYAGRTMEYGKARDVFYQPVHPYSIGLLNAVPRLDSE
                     GAEMLTIPGNPPNLLRLPKGCPFQPRCPHAMEICNNAPPLEAFSPGRLRACFKPVEEL
                     L"
     gene            2973..3977
                     /gene="oppF"
                     /locus_tag="OPV72_003475"
     CDS             2973..3977
                     /gene="oppF"
                     /locus_tag="OPV72_003475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016506804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein tripeptide/oligopeptide ABC transporter
                     ATP binding protein OppF"
                     /protein_id="HCR9915678.1"
                     /translation="MNAVIEQRKVLLEIADLKVHFDIKEGKQWFWQPPKTLKAVDGVT
                     LRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGKVAWLGKDLLGMKADEWREVRSD
                     IQMIFQDPLASLNPRMTIGEIIAEPLRTYHPKLSRQDVRDRVKAMMLKVGLLPNLINR
                     YPHEFSGGQCQRIGIARALILEPKLIICDEPVSALDVSIQAQVVNLLQQLQREMGLSL
                     IFIAHDLAVVKHISDRVLVMYLGHAVELGTYDEVYHNPLHPYTKALMSAVPIPDPDLE
                     RNKKIQLLEGELPSPINPPSGCVFRTRCPLAGPECAQTRPVLEGSFRHAVSCLKVDPL
                     "
     gene            4025..4861
                     /locus_tag="OPV72_003476"
     CDS             4025..4861
                     /locus_tag="OPV72_003476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HCR9915679.1"
                     /translation="MSLSLSSVRRRLYHNLFDLTTRSSRRFEGLCALFALLSVLVIFV
                     ESGVGTEYHLTFDEWHIFVWLELCVTLIFTGEYLLRLFSWPEPAKYVFSFWGFIDLVT
                     ILPLYVMWLWPEISLNYMFAWRAMRAIRVLRILKLLRFMPSLRVFWSAIISARHQLIL
                     FYSFIAIVMIIFGALMYLIEGPKYGFTTLNASVYWAIVTVTTVGYGDITPHTPLGRIV
                     ASVLILIGYSVIAIPTGLITTHMSSAFQKRHWQRKCPQCQQSQHEHSAQYCNRCGSKL
                     PD"
     gene            complement(4909..5238)
                     /locus_tag="OPV72_003477"
     CDS             complement(4909..5238)
                     /locus_tag="OPV72_003477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_448158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciU family protein"
                     /protein_id="HCR9915680.1"
                     /translation="MEMDLNNRLTEDETLEQAYDIFLELAADNLDPADIILFNLQFEE
                     RGGAELFDPAEDWQEHVDFDLNPDFFAEVVIGLADTEDGEINDIFARVLLCREKDHKL
                     CHILWRE"
     gene            complement(5272..6732)
                     /gene="cls"
                     /locus_tag="OPV72_003478"
     CDS             complement(5272..6732)
                     /gene="cls"
                     /locus_tag="OPV72_003478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HCR9915681.1"
                     /translation="MTTFYTVVSWLVILGYWVLIAGVTLRILMKRRAVPSAMAWLLII
                     YILPLVGIIAYLSVGELHLGKRRAERARAMWPSTAKWLNDLKACKHIFAQENSSVASS
                     LFKLCERRQGIAGVKGNQLQLLTDSDDVMQALIRDIQLARHNIEMVFYIWQPGGMADQ
                     VAESLMAAARRGIHCRLMLDSAGSVAFFRSPWAAMMRNAGIEVVEALKVNLMRVFLRR
                     MDLRQHRKMVMIDNYIAYTGSMNMVDPRFFKQDAGVGQWVDLMARMEGPVATAMGIVY
                     SCDWEIETGKRILPPPPDVNIMPFEQASGHTIHTIASGPGFPEDLIHQALLTATYAAR
                     EYLIMTTPYFVPSDDLLHAICTAAQRGVDVSIILPRKNDSLLVGWASRAFFSELLAAG
                     VKIYQFEGGLLHTKSVLVDGELSLVGTVNLDMRSLWLNFEITLVIDDTGFGADLAAVQ
                     DDYISRSRLLDARLWVKRPLWQRITERLFYFFSPLL"
     gene            6875..7048
                     /locus_tag="OPV72_003479"
     CDS             6875..7048
                     /locus_tag="OPV72_003479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciY family protein"
                     /protein_id="HCR9915682.1"
                     /translation="MKRSRTEVGRWRMLRQASRRKARWLEGQSRRNMRIHTIRKCIFN
                     RQRNSLLFAIHGV"
     gene            complement(7092..7388)
                     /locus_tag="OPV72_003480"
     CDS             complement(7092..7388)
                     /locus_tag="OPV72_003480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciI family protein"
                     /protein_id="HCR9915683.1"
                     /translation="MLYVIYAQDNANSLEKRLSVRPAHLARLQLLHDEGRLLTAGPMP
                     AVDSNDPGVAGFTGSTVIAEFESLEAAQSWADADPYVAAGVYAQVSVKPYKKIF"
     gene            7612..8340
                     /gene="tonB"
                     /locus_tag="OPV72_003481"
     CDS             7612..8340
                     /gene="tonB"
                     /locus_tag="OPV72_003481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB system transport protein TonB"
                     /protein_id="HCR9915684.1"
                     /translation="MTLDLPRRFPWSTLLSVGIHGAVVAGLLYTSVHQVIELPAPAQP
                     ITVTMVSPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKP
                     KPEPVKKVEEQPKREVKPAAPRPASPFENSAPMRPTSGTASATSKPAVSVPTGPRALS
                     RNQPQYPARAQALRIEGRVKVKFDVTAAGRVENVQILSAQPANMFEREVKNAMRKWRY
                     EAGKPGSGLVVNIIFRLNGAAQIE"
     gene            complement(8399..8800)
                     /gene="yciA"
                     /locus_tag="OPV72_003482"
     CDS             complement(8399..8800)
                     /gene="yciA"
                     /locus_tag="OPV72_003482"
                     /EC_number="3.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioester hydrolase YciA"
                     /protein_id="HCR9915685.1"
                     /translation="MTTMDNTPQGELVLRTLAMPADTNANGDIFGGWLMSQMDIGGAI
                     LAKEIAHGRVVTVRVEGMTFLRPVAVGDVVCCYARCVKRGTTSISINIEVWVKKVASE
                     PIGQRYKATEALFIYVAVDPDGKPRPLPVQG"
     gene            complement(8961..9500)
                     /locus_tag="OPV72_003483"
     CDS             complement(8961..9500)
                     /locus_tag="OPV72_003483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation protein A"
                     /protein_id="HCR9915686.1"
                     /translation="MKQFLDFLPLVVFFAFYKLYDIYAATSALIVATAIVLIYSWVRY
                     RKIEKMALITFVLVAVFGGLTLFFHNDEFIKWKVTVIYALFAGALLISQWVMKKPLIQ
                     RMLGKELALPQQVWSKLNLAWALFFIACGLANIYIAFWLPQNIWVNFKVFGLTALTLI
                     FTLLSGVYIYRHLPQEDKS"
     gene            complement(9557..10300)
                     /locus_tag="OPV72_003484"
     CDS             complement(9557..10300)
                     /locus_tag="OPV72_003484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0259 family protein"
                     /protein_id="HCR9915687.1"
                     /translation="MSITAKSVYRDAGNFFRNQFITILLVSLLCAFITVVLGHAFSPS
                     DAQIAQLSEGEHLAGSAGLFELVQNMTPEQQQILLRASAASTFSGLIGNAILAGGIIL
                     MIQLVSAGHRVSALRAIGASAPALPKLFILIFLTTLLVQIGIMLIVVPGIIMAIVLAL
                     APVMLVEEKMGVFAAMRSSMRLAWANMKLVAPAVIGWLLAKTLLLLFAPSFAVLTPNV
                     GAVLANTLSNLISAVLLIYLFRLYMLIRQ"
     gene            complement(10326..10730)
                     /locus_tag="OPV72_003485"
     CDS             complement(10326..10730)
                     /locus_tag="OPV72_003485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HCR9915688.1"
                     /translation="MSVLNPCMTCGACCAYFRVSFYWAEGDDASGRVPASLTEPVTPF
                     LRCMAGTNQKQPHCKALIGTPGENVSCAIYENRPSTCREFSISGEGGEVNEACNRARA
                     RYGLPPLYKDMLFHTTADAATVELSRVQLPAN"
BASE COUNT         2608 a         2746 c         2893 g         2638 t
ORIGIN      
        1 acatgggaca actgcggttg tcccatggtg tcttttttca tcgcactata actttccctg
       61 gcggatcttt tgtcacgtcc gggaagtaaa ggcacaggcc agaaggtacg ggcaatgttg
      121 aaatttattt tacgccgctg tctggaagcg attccgacgc tgtttattct tattaccatc
      181 tctttcttta tgatgcgcct cgcgccgggg agtcctttta ccggcgagcg cgcattgccg
      241 ccggaagtgc tggccaatat tgaagcaaaa tatcatctga acgatcccat catgacgcag
      301 tacttcagct acctgaagca gctggcgcat ggcgattttg gaccatcgtt taaatataaa
      361 gattacacgg tcaacgatct ggttgccgcc agcttccccg tttcggcgaa acttggcgcc
      421 gccgcttttt tgctggcggt cattattggt gtcagcgctg gcgtgattgc cgcgctaaag
      481 caaaatacgc gatgggatta tacggtgatg ggatttgcca tgaccggcgt cgttatcccc
      541 agttttgtgg tagcgccgct actggtgatg gtctttgcaa taaccttgca atggctgctt
      601 ggcggcggct ggaacggcgg ggcgttaaaa tttatgatcc tgccgatggt cgcgctttca
      661 ctggcctata ttgccagcat cgctcgtatt acgcgcggct caatgattga agttctgcat
      721 tcgaacttta ttcgtaccgc gcgggcaaaa ggattaccga tgcgcagaat catcttccgc
      781 catgcgttaa aacctgcgct gctgccggtt ttatcctata tggggccagc ctttgtcggc
      841 attattaccg gctcaatggt gattgaaacg atttatggct taccgggcat tgggcagctt
      901 ttcgttaatg gcgcgctcaa ccgcgattac tcgctggtgt taagtttgac cattttagtc
      961 ggggcgctga ccatattgtt taacgccatt gtcgatgtgc tctatgccgt tatcgacccg
     1021 aaaattcgct attgatactg gagctcgcga tgatgttaag taagaaaaac agcgagacgc
     1081 tggaaaattt cagtgaaaag ctggaggtgg aaggtcgcag cctttggcaa gatgcccgtc
     1141 ggcgctttat gcataaccgt gcggcggtgg ccagtcttat tgtcctgttt ctgatagccc
     1201 tattcgtgac agtagcgcct atgctgtcgc aatttaccta tttcgatacc gactggggca
     1261 tgatgtccag cgcgccggat atggcgtccg gccactattt cggcactgac tcttccgggc
     1321 gcgatctgtt ggtgcgcgtt gccatcggcg ggcgtatctc attgatggtc gggattgccg
     1381 ccgcgctggt ggcggtcatt gtcggaacgc tgtatggctc gctgtccggg tatctgggcg
     1441 gcaaaattga ttctgtgatg atgcgtttgt tggagatcct caactcgttc ccgtttatgt
     1501 tctttgtgat tttgctggtg acgttttttg gcagaacatt ctgttgattt tcgtcgccat
     1561 cggcatggtc tcctggcttg atatggcgcg tatcgtgcgt ggccaaaccc taagtcttaa
     1621 acgtaaagag ttcatcgaag ccgcgcaggt gggtggtgtg tcgaccgcca gcattgtgat
     1681 ccgccatatt gtgcctaacg tcctgggcgt agtggtagtg tatgcatcgt tgctggtgcc
     1741 cagcatgatt ctgtttgagt ctttcctcag tttcctgggg cttgggacgc aggaaccgtt
     1801 aagcagttgg ggagcgttgt tgagcgatgg cgcaaattca atggaagtct taccgtggct
     1861 gctgctgttt ccggctggct ttctcgtggt gacgttattc tgttttaact ttattggcga
     1921 tggcctgcgt gatgccctcg acccaaaaga tcgttaagga gtacagccat gagcttatca
     1981 gaaaccgcaa ctcaggcgcc gcaaccggcg aatgtactgc tggaggtaaa cgatcttcgt
     2041 gttacgttcg ctacgcctga tggcgatgtg acggcggtca acgatctgaa ctttacgctt
     2101 cgcgctggag aaacgttagg tattgttggc gagtctggat cggggaaatc gcaaacggcg
     2161 ttcgcattaa tgggactgct ggcgacgaat ggtcgaatcg gcggttccgc gacctttaac
     2221 ggacgtgaaa ttcttaatct acctgagcgc gaactgaata cgctgcgcgc agaacagatt
     2281 tcgatgattt ttcaggaccc gatgacctcg ctaaatcctt atatgcgcgt tggggagcag
     2341 ttaatggaag tcctgatgct gcataaagga atgagcaaag cggaagcttt tgaagagtcc
     2401 gtcagaatgc tggatgccgt aaaaataccg gaagcgcgca aacggatgaa aatgtacccg
     2461 cacgaatttt ccggcggaat gcgtcaacgt gtgatgattg cgatggcgct gttgtgcagg
     2521 ccgaaactgc ttattgccga tgagcctacc accgcgcttg atgttaccgt gcaggcgcag
     2581 attatgacct tgcttaatga gctaaagcgc gaatttaata ccgccattat catgattacc
     2641 cacgatctgg gcgtggtcgc gggtatttgc gataaggtcc tggtaatgta tgccgggcgt
     2701 accatggaat acggtaaggc gcgcgatgtc ttttatcagc ccgttcatcc gtattcgata
     2761 ggcttgctta atgcggtgcc gcgtctggat agcgaggggg cggaaatgct gacgattccg
     2821 ggcaatcctc ccaatttatt gcgtttgcct aaaggttgtc cgttccagcc gcgttgtcct
     2881 catgcgatgg agatctgcaa taatgcgccg ccacttgaag cgttcagtcc tggtcgcttg
     2941 cgcgcctgtt ttaaaccggt ggaggaactg ctatgaatgc tgtgattgaa caacgtaaag
     3001 ttctcctcga aatcgccgat ctaaaagtac attttgatat caaagaaggg aagcagtggt
     3061 tctggcaacc gccgaaaacc ctgaaagcgg tggacggcgt tacgctacgc ctgtatgaag
     3121 gcgaaacgct tggcgtggtg ggggaatccg gctgcggcaa gtcgacgttt gcgcgcgcca
     3181 ttattggtct ggtgaaggcg acagacggta aagtcgcctg gctgggaaaa gatctgttgg
     3241 gcatgaaagc ggatgagtgg cgcgaggtgc gcagcgacat ccagatgatt ttccaggacc
     3301 cgctggcgtc actcaacccg cgaatgacga ttggcgaaat tatcgctgaa ccgctgcgca
     3361 cttatcatcc taagctttcg cgccaggacg tgcgtgaccg cgtgaaagcc atgatgctga
     3421 aagtggggct gctgccgaat ctcatcaacc gttatcccca tgagttttcc ggggggcagt
     3481 gccagcgcat cggtatcgcc cgggcgttga tcctggagcc taagctcatt atttgcgatg
     3541 agccggtgtc ggcgctggac gtttctattc aggcgcaggt ggtgaatttg ctccagcagt
     3601 tacagcgaga gatggggctg tcgttgattt ttattgcgca cgatctggcg gtcgtaaagc
     3661 acatatccga tcgtgtcctg gtgatgtatc tcggtcatgc ggtagaattg ggcacctatg
     3721 atgaggtgta ccataatcca ctgcatcctt ataccaaagc gctgatgtcg gcggtaccga
     3781 ttcccgatcc cgatctggag cgaaataaga agatacaatt gctggagggc gaattacctt
     3841 cgcccattaa cccgccttcc ggctgcgtgt tccgtacacg ctgtccgcta gccgggccag
     3901 aatgcgcgca aacgcgaccg gtgttggaag ggagttttcg ccatgccgtt tcctgcctta
     3961 aagtagaccc gttataatcg caagggctga caattcgtca gcccttcttt taggtgaggt
     4021 taccgtgtca ctttctttgt cgtcggttcg ccgtcgtctt tatcataatc tgttcgattt
     4081 gactacgcgc tcaagtcgcc gttttgaagg gttatgcgcg ctgtttgcgc tgcttagcgt
     4141 actggtcatt tttgttgaat caggcgtagg aacggaatat cacctgacat ttgatgaatg
     4201 gcatattttt gtctggctgg agctgtgcgt taccctgata tttaccggtg aatacttgct
     4261 cagactgttt agttggcccg aaccggcaaa atacgttttt agtttctggg gatttattga
     4321 tctggtgacg attttgccgc tgtacgtcat gtggctatgg ccggaaatta gcctgaacta
     4381 tatgtttgcc tggcgcgcta tgcgagcgat tcgcgtgctg cgtattctta aactgctacg
     4441 ttttatgcca tccctgcgcg tattctggag cgccattatt agcgcgcgtc atcagcttat
     4501 tctgttctat tcatttattg cgatcgtgat gattattttc ggtgccctga tgtatcttat
     4561 tgaaggaccg aaatatggct tcacgacgct taatgcctcg gtgtattggg cgatagtgac
     4621 agtcacaacc gtggggtacg gtgatattac gccgcatacg ccgctgggac gtattgtcgc
     4681 gtcggtgctt attttgattg gttattcggt gattgcgatt cctacaggac tgattaccac
     4741 gcacatgagc agcgcgtttc aaaaacgtca ctggcagcga aaatgtccgc agtgccagca
     4801 aagccagcat gaacatagcg cgcaatattg taaccgatgc ggcagtaagc taccggatta
     4861 aacaggcttg ccggagggcg ctatcagacg ccatccggcc tgaaccgctt attcgcgcca
     4921 gagaatatgg cacagcttgt ggtccttttc ccggcacagc agaacgcggg caaaaatgtc
     4981 gttaatttcg ccgtcttcgg tatccgccag gccaatcacc acctcggcaa aaaagtctgg
     5041 attcaggtca aaatcgacgt gctcttgcca gtcttcagcg ggatcaaaca actccgcgcc
     5101 gccgcgctcc tcgaattgca aattgaacag aatgatatca gccggatcaa gattatccgc
     5161 cgccagctca agaaaaatat cgtaagcctg ctcaagcgtt tcgtcttcag tcaggcgatt
     5221 gttcagatcc atttccatag tgactacctg tttactcatg ttggtcacgt tttacagcaa
     5281 tggactaaag aagtaaaaca atcgctcggt aatacgctgc cataacggac gttttaccca
     5341 caaacgcgca tctaacaggc gggagcgcga aatataatcg tcctgtaccg cagccagatc
     5401 ggcgccgaaa cccgtatcat caatgaccag cgtaatctcg aaattaagcc acaggctacg
     5461 catgtcgaga ttcacggtac cgaccaggct cagttcgcca tcgaccagca cgcttttggt
     5521 atgcaacagc ccgccttcga actgatagat tttcacgccc gccgccagta actcgctgaa
     5581 aaaggcgcga ctggcccagc cgacgagcag tgaatcattt ttacggggca ggataatact
     5641 gacatccacg ccgcgctgcg cagcggtaca aatggcgtgc agcagatcgt cgctggggac
     5701 gaaatatggc gtggtcataa ttaaatattc gcgcgcagca taggtggcgg ttaatagtgc
     5761 ctggtgaatg agatcttccg gaaaaccagg accggaagca atggtatgaa tggtatgccc
     5821 gctggcctgc tcaaacggca taatattcac gtccggcggg ggaggcagaa tgcgtttacc
     5881 cgtctcgatt tcccaatcgc aggagtaaac aatccccatt gctgtcgcca cgggaccctc
     5941 catccgcgcc atcaaatcga cccattgtcc aacgccggca tcctgtttga aaaaacgcgg
     6001 gtccaccata ttcatactgc cggtataggc gatgtaattg tcaatcatca ccattttacg
     6061 gtgctggcga agatccatac ggcgtaaaaa gacgcgcatc agattcacct tcagcgcctc
     6121 tacgacttca atgccagcgt tacgcatcat ggccgcccag gggctgcgga agaaagcgac
     6181 gctacccgcg gaatccagca taagccggca atggatgccg cggcgggcgg cggccattag
     6241 cgattcagcg acctgatccg ccatgccgcc tggctgccag atgtaaaaca ccatttcgat
     6301 attatgccgc gccagttgga tatcgcgaat aagcgcctgc atgacatcat cggagtcggt
     6361 aagtaattgc aactggttgc ctttgacgcc cgcaatcccc tgacgtcgtt cgcacagctt
     6421 aaacaaggac gatgcgacgc tactgttttc ttgcgcgaaa atgtgtttgc aggctttgag
     6481 gtcattcaac catttggcgg tagacggcca catggcgcgg gcacgctcgg cgcgacgttt
     6541 gcctaaatgc aattcgccca cggacaaata ggcgatgatc ccgaccagcg gaaggatata
     6601 gatgattaac aaccaggcca ttgcggaggg aactgcgcgc cgtttcatta gaatacgtaa
     6661 tgtgacgccg gcaatgagaa cccagtatcc caaaatgacc agccaactca ccacggtgta
     6721 gaaggttgtc ataactttaa aaatccttta gaaagcgtgt tgttaagagt ttacgcgtca
     6781 ggattcacat ggcaaataaa aacacgggaa aagcgctggt ctgcatccgg cgagggggta
     6841 taatggcgct tctgttacag tgagagtcgt aaacatgaag cgtagtagaa cggaagtggg
     6901 gcgctggcga atgctacgtc aggcgagccg ccgtaaagcg cgttggcttg aagggcaatc
     6961 acgccgtaat atgcgtatcc atactatcag gaaatgcatc tttaatcgtc agcgtaattc
     7021 attactcttt gcgattcacg gtgtgtgagc cagaaagggc accgtatgcg gtgcccaaca
     7081 ggccatcctt ttcaaaagat cttcttatac ggtttgaccg aaacctgcgc atagacgccc
     7141 gctgcgacgt agggatccgc atcagcccag gattgcgctg cttctaaaga ttcaaattca
     7201 gcaatcaccg ttgacccggt aaatccggct accccaggat cgttactgtc cactgcgggc
     7261 atcggcccgg cagttaataa tcgcccttca tcatgcagaa gttgcaggcg cgccagatgc
     7321 gcgggccgta ccgagaggcg tttttcaagc gagttggcat tatcctgagc gtaaataaca
     7381 tacagcacgg gtagagctcc ttaatcggta aaagttgctg attacgttat tggaaagggc
     7441 atttaactgc aatgtaaaga taccgacttt gttaaacatg cacattttgt gtggtgtttt
     7501 tgtgcaatat catcttttaa atgccgctat cggcaatgcc ttattgaata tgattgctat
     7561 ttgcatttaa aattcagctc tggtttttca actgaaacga ttatgacttc aatgaccctt
     7621 gatttacctc gtcgctttcc ctggtcgaca ctcctttccg taggcattca tggtgctgta
     7681 gtggcaggtt tgctctatac ctcggtacat caggttattg aattgcctgc gccagcgcag
     7741 cctatcacgg tgacaatggt ttcacccgct gacctggagc cgccccaggc ggttcagccg
     7801 ccgccggagc cggtggttga acccgaaccg gagccagagc cgatccctga accgcctaaa
     7861 gaagcgcccg tggtgattga gaaacccaaa cctaagccaa aacccaagcc aaaaccgaaa
     7921 ccggaaccgg tgaaaaaggt tgaagagcag ccgaagcgcg aagtcaaacc agccgcaccg
     7981 cgtcctgcct caccgtttga aaatagcgcc ccgatgcggc caacaagcgg caccgcatcg
     8041 gcgaccagca agccggcggt gagcgtgccc actggacctc gagctctgag ccgtaaccag
     8101 ccgcagtatc cggcgcgagc acaggcgtta cgtattgaag gccgcgtaaa ggtgaagttt
     8161 gacgtgaccg ctgctgggcg agtggaaaat gtacagattc tatccgcgca gccagccaat
     8221 atgtttgagc gtgaagttaa gaatgcgatg cgaaaatggc gctatgaagc aggcaagccg
     8281 ggttccgggc tggtggtcaa tattatcttc cgtctgaacg gtgcggcgca gattgagtaa
     8341 tctctggcgc cgccagtagg aatataccat cacctgctgg cggcgtaagc gggtatactt
     8401 aaccctgaac cgggagcggg cgaggtttac cgtccggatc gacggcaaca taaataaaca
     8461 gcgcctcggt ggccttgtag cgctgtccaa tcggttctga cgcgactttt ttcacccaga
     8521 cttcaatatt gatgctaata gacgtcgtac cgcgtttaac gcagcgcgcg tagcagcata
     8581 cgacatcgcc aaccgcgacg gggcgcagaa atgtcattcc ttccacgcgt acggttacaa
     8641 cccgaccgtg cgcgatctct ttggccagta tcgcgccgcc aatatccatt tgcgacatca
     8701 gccagccgcc aaaaatatcg ccgttcgcat tggtatcggc aggcatggcc aatgtacgta
     8761 aaaccagctc gccctgagga gtattatcca ttgttgtcat tgtaaaaccg actatcagaa
     8821 aaaattacag ccgcgatgct actatgaata ttgtgtggag aatagtggga ataaaggtac
     8881 tgacgggaaa gcgcagggcg taaaggcgga gaaaatatcg ccaggcgttc gcagtctggc
     8941 gatgataagt cacgggaggg ttatgattta tcttcctgtg gcagatgccg gtagatatag
     9001 acgccgctca gcagggtaaa aatgagcgtc agcgccgtga gtccgaagac cttaaagtta
     9061 acccagatat tttgcggcaa ccagaaggcg atataaatgt tagccagacc gcacgcaata
     9121 aaaaacagcg cccacgccag gttcagcttt gaccagacct gctgcggcaa cgccagttct
     9181 ttacctaaca tacgttggat taacggtttt ttcatcaccc actggcttat taacagcgcg
     9241 ccggcgaaca gcgcataaat aaccgtcacc ttccatttaa taaattcatc gttatggaag
     9301 aagagcgtca gaccgccgaa gacggcaacc agaacaaagg taatcagcgc catcttctct
     9361 attttccgat agcgcaccca gctataaatc agcacgattg ccgttgcgac aatcagtgcg
     9421 gaggtcgccg catagatgtc ataaagttta taaaacgcaa aaaagacaac cagcggtaaa
     9481 aaatccagaa actgcttcat tcttcgattc catcatcaac gagcgtcgaa tgcgccgcgt
     9541 aacggcgcat tgcggattat tggcgaatca acatatacag gcggaataag tagataagca
     9601 atactgcgga aatcagattg ctcaacgtat tcgccagtac agcgcctaca tttggggtca
     9661 gtacagcgaa gctgggcgcg aacagcaata gcaatgtttt agccagtaac cagcctatca
     9721 ccgcaggcgc gaccagtttc atgttagccc aggctaaacg catactgctg cgcattgcgg
     9781 caaacacgcc cattttctct tcaaccaaca tcactggcgc aagcgccagc acaatggcca
     9841 taataatccc cggaacgaca atcagcatta taccgatttg cactaacagg gtagtcagaa
     9901 aaataagaat aaacagttta ggcaatgcag gggcgctggc gccgatagcg cgcagcgcgc
     9961 taacccgatg tcccgctgaa actaactgaa tcatcaggat gataccgccg gccagaatag
    10021 cgttgccgat aagcccggaa aacgtcgagg cggcagaggc gcgcaacagg atctgttgct
    10081 gctccggcgt catattttgt accagctcaa acaggccagc gctgcctgcc agatgttctc
    10141 cttcactgag ttgcgcgatt tgcgcatcgc tgggtgaaaa ggcatgacct aagaccaccg
    10201 tgataaatgc gcacagcaac gaaaccagca agatagtaat aaattgattt cggaaaaaat
    10261 ttccggcgtc acggtaaacg gacttcgccg tgatagacat gcactctcct tgagttttgc
    10321 aggtgttaat ttgcgggcaa ttgtaccctg gataactcta cagtggcagc atcagcagtt
    10381 gtatggaaaa gcatatcttt gtaaagcggc ggtaatccgt atcgcgcgcg ggcgcgatta
    10441 cacgcctcat tcacttcgcc tccttcgccc gatatcgaaa attcgcgaca ggttgaaggg
    10501 cggttttcat aaatagcgca actgacgttt tcacccggcg tgccaattag cgctttacag
    10561 tgcggctgtt tttggttggt accggccata caacgtaaaa aaggggtaac aggctcggtt
    10621 aatgacgccg gaacgcgtcc gctggcatcg tcgccttcag cccaataaaa ggagacacga
    10681 aaataggcac aacaggcacc gcatgtcatg catgggttaa gaacgctcat gattcacctg
    10741 caaaaaactc acgtatcaat agattacaac ggaaattaat ctgtcccgca gtgttcgcga
    10801 atcttaccgc cacgcgccat tgcgggacat tgattacctt agccagcctt tatcgccagg
    10861 gcaacaggag cagacaaata tttgc
//
LOCUS       DAJVBX010000164        10876 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.164, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000164 DAJVBX010000000
VERSION     DAJVBX010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 10876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10876
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.164"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(43..1512)
                     /gene="lysP"
                     /locus_tag="OPV72_003486"
     CDS             complement(43..1512)
                     /gene="lysP"
                     /locus_tag="OPV72_003486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine-specific permease"
                     /protein_id="HCR9915689.1"
                     /translation="MGSKTKTTEAPALRRELKARHLTMIAIGGSIGTGLFVASGATIS
                     LAGPGGALFSYILIGLMVYFLMTSLGELAAYMPVSGSFATYGQNYVEEGFGFALGWNY
                     WYNWAVTIAVDLVAAQLVMGWWFPDTPGWIWSALFLCVIFLLNYISVRGFGEAEYWFS
                     LIKVATVIIFIIVGVAMIIGIFKGVEPVGWSNWTTGDAPFAGGFAAMIGVAMIVGFSF
                     QGTELIGIAAGESENPEKNIPRAVRQVFWRILLFYVFAILIISLIIPYTDPNLLRNDV
                     KDISVSPFTLVFQHAGLLSAAAIMNAVILTAVLSAGNSGMYASTRMLYTLACDGKAPR
                     IFAKLSRGGVPRNALYATTVIAGLCFLTSMFGNQTVYLWLLNTSGMTGFIAWLGIAIS
                     HYRFRRGYVLQGYDVNDLPYRSGFFPLGPIFAFVLCLIITLGQNYEAFLKDTIDWGGV
                     AATYIGIPLFLLIWFGYKLIKGTHFVRYSEMHFPERVKK"
     gene            complement(1702..2565)
                     /locus_tag="OPV72_003487"
     CDS             complement(1702..2565)
                     /locus_tag="OPV72_003487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCR9915690.1"
                     /translation="MHITLRQLEVFAEVLKSGSTTQASVMLSLSQSAVSAALTDLEGQ
                     LGVQLFDRVGKRLVVNEHGRLLYPRALALLEQAVEIEQLFREDNGAIRVYASSTIGNY
                     ILPAMIARYRQHYPALPLELSVGNSQDVINAVLDFRVDIGLIEGPCHSTEIISEPWLE
                     DELVVFAAPSSPLTQGPVTLEQLAASPWILRERGSGTREIVDYLLLSHLPRFHMAMEL
                     GNSEAIKHAVRHGLGISCLSRRVIAEQLQAGTLGEVAVPLPRLVRTLWRVHHRQKHLS
                     NALQRFLSYCE"
     gene            2686..3735
                     /locus_tag="OPV72_003488"
     CDS             2686..3735
                     /locus_tag="OPV72_003488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family protein"
                     /protein_id="HCR9915691.1"
                     /translation="MTELTLQNHRRTMWHFIPGLALSAVITGVALWGGAIPAVAGAGF
                     SALTLAILLGMVIGNTVYPQIWKQCDGGVLFAKQHLLRLGIILYGFRLTFSQIADVGI
                     SGIVIDVLTLSSTFMLACFLGQKVFGLDRHTSWLIGAGSSICGAAAVLATEPVVKAEA
                     SKVTVAVATVVIFGTIAIFLYPAMYPLLAHWFSPETYGIYIGSTMHEVAQVVAAGHAV
                     SPDAENAAVIAKMLRVMMLAPFLIILAARVKQLSPATGAEKSKITIPWFAIFFIVVAI
                     FNSFHLLPKAVVDMLVTLDTVLLAMAMAALGLTTHVSALKKAGAKPLLMALALFAWLI
                     IGGGAINVLIHSLIA"
     gene            3814..4671
                     /gene="nfo"
                     /locus_tag="OPV72_003489"
     CDS             3814..4671
                     /gene="nfo"
                     /locus_tag="OPV72_003489"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HCR9915692.1"
                     /translation="MKYIGAHVSAAGGLANAPARAAEIGATAFALFTKNQRQWRAAPL
                     TPQVIDDFKIACEKYHFSAAQILPHDSYLINLGHPVSEALEKSRDAFLDEMQRCEQLG
                     LTLLNFHPGSHLMQIAQEDCLARIAESINIALAQTEGVTAVIENTAGQGSNLGFEFEQ
                     LAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPEACEKTFAEFGKIVGFQYLRGMHLN
                     DAKSAFGSRVDRHHSLGEGNIGHDAFRWIMQDARFDGIPLILETINPDIWAEEIAWLK
                     AQQIAEAMA"
     gene            complement(4736..6424)
                     /gene="fruA"
                     /locus_tag="OPV72_003490"
     CDS             complement(4736..6424)
                     /gene="fruA"
                     /locus_tag="OPV72_003490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIBC"
                     /protein_id="HCR9915693.1"
                     /translation="MKTLLIIDANLGQARAYMAKTLLGAAAHKANLEIIDNPNDAELA
                     IVLGESLPNDNALNGKKVWLGDIGRAVAHPELFLSEAKSHATPYSAPAAAAPAASGGP
                     KRVVAVTACPTGVAHTFMAAEAIETEAKKRGWWVKVETRGSVGAGNAITPEEVAEADL
                     VIVAADIEVDLAKFAGLPMYRTSTGLALKKTAQELDKAVAEATPYQPAGKASQAATEG
                     KKESAGAYRHLLTGVSYMLPMVVAGGLCIALSFAFGIEAFKVPDTLAAALMQIGGGSA
                     FALMVPVLAGYIAFSIADRPGLTPGLIGGMLAVSTGSGFIGGIIAGFLAGYMAKLIST
                     KLKLPQSMEALKPILIIPLISSLVVGLAMIYLIGKPVAGILEGLTHWLQTMGTANAVL
                     LGAILGGMMCTDMGGPVNKAAYAFGVGLLSTQTYAPMAAIMAAGMVPPLALGLATMVA
                     RRKFDKAQQEGGKAALVLGLCFITEGAIPFAARDPMRVLPCCIVGGALTGAISMAVGA
                     KLMAPHGGLFVLLIPGAITPVLGYLLAIVAGTLVAGLAYAVLKRPETEVAAKAA"
     gene            complement(6441..7379)
                     /gene="fruK"
                     /locus_tag="OPV72_003491"
     CDS             complement(6441..7379)
                     /gene="fruK"
                     /locus_tag="OPV72_003491"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HCR9915694.1"
                     /translation="MSRRVATITLNPAYDLVGFCPEIERGEVNLVKTTGLHAAGKGIN
                     VAKVLKDLGIDVTVGGFLGKDNQDGFQQLFSELGIANRFQVVQGRTRINVKLTEKDGE
                     VTDFNFSGFDVTPADWERFVNDSLSWLGQFDMVCVSGSLPAGVSPEAFTDWMTRLRSQ
                     CPCIIFDSSREALVAGLKAAPWLVKPNRRELEIWAGRKLPEMKDVIDAAHALREQGIA
                     HVVISLGAEGALWVNASGEWIAKPPAVDVVSTVGAGDSMVGGLIYGLLMRESSEHTLR
                     LATAVAALAVSQSNVGITDRPQLAAMMARVDLQPFN"
     gene            complement(7379..8509)
                     /gene="fruB"
                     /locus_tag="OPV72_003492"
     CDS             complement(7379..8509)
                     /gene="fruB"
                     /locus_tag="OPV72_003492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused PTS fructose transporter subunit IIA/HPr
                     protein"
                     /protein_id="HCR9915695.1"
                     /translation="MFQLSVQDIHPGEQAGNKEEAIRQIAAALAQAGNVAGGYVDGML
                     AREQQTSTFLGNGIAIPHGTTDTRDQVLKTGVQVFQFPQGVTWGEGQVAYVAIGIAAS
                     SDEHLGLLRQLTHVLSDDSVAEQLKSATTAEELRALLMGEKQSEQLKLDNETMTLDVI
                     ASSLVTLQALNAARLKEAGAVDAAFVAKTINDSPMNLGQGIWLNDSAEGNLRSAVAVS
                     RATQAFDVEGEKAALLVTVAMNDEQPIAVLKRLGDLLLNNKADRLLSADAATLLALLT
                     SDDALTDDVLSAEFVVRNEHGLHARPGTMLVNTIKQFNSEITVTNLDGTGKPANGRSL
                     MKVVALGVKKGHRLRFTAQGEDAEQALKAIGDAIAAGLGEGA"
     gene            8879..10060
                     /gene="setB"
                     /locus_tag="OPV72_003493"
     CDS             8879..10060
                     /gene="setB"
                     /locus_tag="OPV72_003493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar efflux transporter SetB"
                     /protein_id="HCR9915696.1"
                     /translation="MHNSPAAAAPKSFDLTSTAFLIVAFLTGIAGALQTPTLSIFLTD
                     EVHARPGMVGFFFTGSAVIGIIVSQFLAGRSDKKGDRKKLIVFCCVLGMLACVLFAWN
                     RNYFILLFIGVFLSSFGSTANPQMFALAREHADRTGREAVMFSSILRAQVSLAWVIGP
                     PLAYALAMGFSFTVMYLSAAVAFIVCGVMVWFFLPSMRKDAPLATGTLEAPRRNRRDT
                     LLLFVICTLMWGTNSLYIINMPLFIINELHLPEKLAGVMMGTAAGLEIPTMLIAGYFA
                     KRLGKRLLMCIAVVAGLCFYAGMLLAHAPATLLGLQLLNAIYIGILGGIGMLYFQDLM
                     PGQAGSATTLYTNTIRVGWIIAGSLAGIAAEIWNYHAVFWFALVMIVATMFCLARIKD
                     V"
     gene            complement(10125..10790)
                     /locus_tag="OPV72_003494"
     CDS             complement(10125..10790)
                     /locus_tag="OPV72_003494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915697.1"
                     /translation="MRGENSEIDLVDVSLFLIRKWLSIVIATFIFVAIGYVFVSVHHD
                     TKVVSITIKPNLDTPATYALCGYANDIQCKTTVILNQFSRFLPAEYKNKISFDAKNQL
                     VLFKAQGREESVNNIISTLKNSVDKMAAWYIDDGDIKRYSVHKNMLQTETYTKLSLLS
                     EAVKNNANIEVIDVAVTPKYKMRLVLVLCGLMGVIFSITGLLCKRALTEYRIEKKTMN
                     DRA"
     gene            complement(10792..>10876)
                     /locus_tag="OPV72_003495"
     CDS             complement(10792..>10876)
                     /locus_tag="OPV72_003495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915698.1"
                     /translation="ARAFIFTLVLLFVISVFGLTISVLKGM"
BASE COUNT         2548 a         3118 c         2669 g         2541 t
ORIGIN      
        1 ggcggcataa agccttatcc ggcctatgac gagaatatta cgttactttt taacgcgttc
       61 cgggaagtgc atttcgctat agcgcacgaa atgcgtgcct tttatcagct tgtagccgaa
      121 ccagataagc aggaacagcg gaataccgat ataggtcgcc gcgacgccgc cccagtcgat
      181 ggtatctttc aggaacgctt catagttctg ccccaacgta ataatcaggc acagtacaaa
      241 ggcgaaaatc ggccccagcg ggaagaaccc ggaacggtac ggcaaatcat tcacatcata
      301 cccttgtaac acgtaaccgc gacggaagcg ataatggcta atggcaatcc ccagccaggc
      361 gatgaagccc gtcataccgg aggtgttcaa cagccacaga tagaccgtct ggttgccgaa
      421 cattgaggtc aaaaagcaaa gaccggcaat cacggtggtg gcataaagcg cattgcgcgg
      481 tacgccgccg cgggacaatt tcgcaaaaat acgcggggcc ttaccgtcac aggccagggt
      541 gtagagcata cgggtcgagg catacatccc ggagttaccc gcagacagta ccgccgtcag
      601 gataaccgca ttcattatcg ccgccgcaga caacaagccc gcatgctgga acactaaggt
      661 aaacggactg acgctaatgt ctttgacgtc gttacgcagc aggtttggat cggtataagg
      721 aatgatcagg ctgataatca aaatcgcgaa aacataaaac agcagaatac gccagaacac
      781 ctgacgcacc gcgcgcggaa tattcttctc cgggttttca gattccccgg cggcaatacc
      841 aatcagctca gttccctgga aagagaagcc cacgatcatc gcgacgccaa tcattgccgc
      901 aaaaccgcca gcgaaaggcg catcgcccgt cgtccagttg ctccagccga ccggctcgac
      961 acctttaaag atgccgataa tcatcgctac gccaacgatg atgaagataa taacggtcgc
     1021 gactttaatt aacgagaacc agtactccgc ctcgccaaaa ccgcgtacag aaatgtagtt
     1081 cagcaagaaa atgacgcaga ggaatagcgc gctccagatc cagcccggcg tgtccgggaa
     1141 ccaccagccc atcaccaatt gtgcggcaac caggtcaaca gcgatagtca ccgcccagtt
     1201 gtaccagtag ttccagccca gcgcgaaacc aaagccttct tccacatagt tctgaccata
     1261 tgtcgcaaac gagccagata ccggcatata ggccgccagc tcgccaagac tggtcatcag
     1321 gaagtagacc atcaaaccaa tcagaatata agaaaacagc gcgccgcctg gccccgccag
     1381 agaaattgtc gcaccagatg caacgaaaag acctgtcccg atggagccgc caatggcaat
     1441 catcgtcagg tgacgcgcct ttaattcgcg acgtagcgcg ggcgcttctg tggttttagt
     1501 tttggaaccc atgtgaaaat gctatccatc caaaaaatga ggcgcgattg taacagacga
     1561 aatactatcc ttccgacaca aatgcgcggt tataagagac cttcatgacc ggccacggat
     1621 tataagtaaa gcagagaata acgtatacgt aagcggatac taaaaatggc gatgccgctc
     1681 gggcagccct cctcttcacc tttattcaca gtaactcaaa aaacgctgca acgcgttaga
     1741 aagatgtttc tgccgatgat gaacacgcca caacgtgcgc accaggcgcg gtaacggcac
     1801 cgcgacttcg cccagggttc ccgcctgaag ttgttcagca atcacccggc gcgataaaca
     1861 gcttatcccc agtccatgac gcaccgcatg tttgatcgct tctgaattcc ccaactccat
     1921 cgccatatga aagcgcggca aatgcgacaa cagcaaataa tcgacaattt cccgcgtacc
     1981 ggaaccgcgc tcgcgtaaaa tccatgggga tgccgcaagc tgttccagcg tcaccggccc
     2041 ctgcgtcagc ggcgaggacg gcgcggcaaa gaccaccagc tcatcttcca gccacggctc
     2101 agagataatc tctgtactgt gacacggccc ttcaatcagg ccgatatcaa cccgaaaatc
     2161 caacaccgcg ttaatcacgt cctggctgtt tcccacgctg agttccagcg gcaaggccgg
     2221 ataatgctgg cgatagcggg caatcatggc gggtaaaatg taattgccga tggtgctact
     2281 ggcataaacc cgtatcgcgc cgttatcttc acgaaatagc tgctcaattt ctaccgcttg
     2341 ctccagcaat gccagcgcgc gcgggtataa caagcgccca tgttcgttga ccaccagccg
     2401 tttccccacc cgatcaaaca actgtacgcc gagctgacct tccagatcgg tgagcgcggc
     2461 gctaacggcg gactgcgata atgacagcat gaccgacgcc tgggttgttg aaccgctttt
     2521 cagtacttca gcaaacactt caagttgtcg tagcgtaata tgcatagtcg tatcccaccg
     2581 atagcgtttc acttaccact tataaagatt aattataaat atataatcaa ttttattttt
     2641 aaaccagatc accgtaacct tattgtccat atacaggaga aggttatgac agaactcacc
     2701 ttgcagaatc atcgtcgtac aatgtggcat tttataccgg ggctcgctct gagcgccgtc
     2761 attacaggag tcgccctgtg gggcggcgct atccctgctg ttgcaggcgc ggggttcagc
     2821 gccctgaccc tggctatcct gctgggtatg gttatcggga ataccgtcta tccacaaata
     2881 tggaaacaat gcgacggcgg cgtgctgttt gcaaaacaac atttactgcg tttagggatt
     2941 atcctttacg gcttccgcct taccttttca caaatcgccg acgtgggtat tagcggtatt
     3001 gtgattgacg tattaacgct ttccagcacg ttcatgctgg cctgcttctt aggccaaaaa
     3061 gtctttggtc tggacaggca taccagctgg ctgattggcg ccggtagcag tatctgcggc
     3121 gcggcggcgg tactggcgac agaaccggtg gtaaaagcgg aagccagtaa ggttactgta
     3181 gccgtcgcga ctgtcgttat tttcggcacc atcgctattt tcctttaccc ggcaatgtat
     3241 ccgctgctgg cgcactggtt cagcccggaa acttacggca tctatatcgg ctcaaccatg
     3301 catgaagtcg cgcaagtggt cgcagcgggt cacgccgtta gcccggatgc ggaaaatgcg
     3361 gcagttatcg ctaagatgct gcgtgtcatg atgctggcgc cgttcctgat cattctggcg
     3421 gcacgcgtta aacagctttc cccggcgacc ggcgcggaaa aaagcaaaat taccattccg
     3481 tggtttgcta ttttcttcat cgtagtggcg atcttcaact ctttccacct gctgccgaaa
     3541 gccgtggtgg atatgctggt gacgctggac acggtactgc tggcgatggc aatggcggcg
     3601 ttgggtctga ccactcacgt tagcgcattg aaaaaagcgg gggcgaaacc gctgctgatg
     3661 gcgctggcat tattcgcctg gctgattatt ggcggtggcg ccattaacgt cctaatccat
     3721 agccttatcg cataaattat tacgtttcac gcctgttaac ccgttatcat agcgttcgta
     3781 atgaaccgtt agcgggttta acaggagtct tttatgaaat acatcggagc gcacgtcagc
     3841 gctgctggcg gtctggctaa cgcccctgcc cgcgcggctg aaattggcgc aacggccttt
     3901 gcgcttttca caaaaaacca gcgtcagtgg cgtgccgccc cccttactcc ccaggtcatt
     3961 gatgacttta aaatcgcctg tgaaaagtat catttctcgg cggcgcaaat ccttccccac
     4021 gatagttacc tgattaatct gggccatccg gtcagtgaag cgctggaaaa atcacgcgat
     4081 gcctttctcg atgaaatgca gcgctgtgaa caactcggct taaccttgct taattttcat
     4141 cccggtagcc atctgatgca gattgcacag gaggattgcc tggcgcggat cgcggaatct
     4201 atcaatattg ccctcgcgca gaccgagggc gttacggcgg ttatcgaaaa tacagccggt
     4261 cagggcagta atctggggtt tgagtttgaa cagttagccg ccatcatcga cggcgtggaa
     4321 gataagtcgc gcgttggcgt ctgtatcgat acctgccatg cctttgccgc tggatacgat
     4381 ctgcgtacgc cagaggcgtg cgaaaaaacg ttcgccgaat tcgggaaaat tgtcggattt
     4441 cagtatttgc gcggaatgca ccttaacgac gccaaaagcg ccttcggtag ccgcgttgac
     4501 cgccatcaca gtctgggtga aggcaatatc ggccacgatg cgtttcgttg gattatgcag
     4561 gatgcgcgtt ttgacggtat tccgctgata ctggagacca tcaatcctga tatctgggcg
     4621 gaagagattg cgtggttaaa agcccagcaa attgccgaag cgatggcctg acgctcaatg
     4681 ttcttcaggc aataaaaaag gcagagcgcg ctctgccttt tttagcgtgt ttctcttatg
     4741 ccgcttttgc cgcgacttcc gtctccggac gtttcaggac ggcataagcc agtcctgcca
     4801 ccagcgtacc ggccacaatt gccagcaggt atcccaatac cggcgtaatt gcgcctggga
     4861 taagcagaac aaacagaccg ccatgcggcg ccatcaattt tgcgcctacc gccatagaaa
     4921 tagccccggt caacgcgccg ccaacgatac agcacggcag tacacgcatc gggtcgcgcg
     4981 ccgcaaacgg aatagcgcct tcagtgataa agcacagccc cagcaccaac gccgctttac
     5041 cgccttcctg ctgcgctttg tcgaacttac gacgcgccac catcgtcgcc agacccagcg
     5101 ctaacggcgg taccatacct gcggccatga tcgccgccat cggcgcgtaa gtttgcgtac
     5161 tcagcagacc aacgccaaac gcatacgccg ctttgttcac cgggccgccc atgtcggtac
     5221 acatcatccc gccgagaatc gcgcccaaca gcaccgcgtt tgccgtcccc atggtttgca
     5281 gccagtgggt gagcccttcc agaatcccgg caaccggttt accgatcagg taaatcatcg
     5341 ccagccccac caccagactg gaaattaacg ggatgatcag gattggcttc agcgcttcca
     5401 tactttgcgg aagtttcagt ttggtactga taagcttcgc catatacccg gcaaggaagc
     5461 cggcaatgat cccgccgata aaaccggaac cggtgctaac cgccagcata ccgccaatca
     5521 gacctggcgt aaggccaggg cgatccgcga tggagaaagc gatataaccc gccagtaccg
     5581 gcaccatcag cgcaaacgcc gaaccgccgc caatctgcat cagcgccgcc gccagcgtgt
     5641 ccggcacctt aaaggcttca ataccaaagg cgaaggaaag cgcaatacac agtcccccgg
     5701 caaccaccat aggcagcatg taagaaacgc ccgtcaacag atgccggtat gcgccagcgc
     5761 tctctttctt cccttcggtc gccgcttgcg atgccttacc cgccggttga tacggcgtcg
     5821 cttccgctac ggctttatcc agctcctgcg ccgtcttttt cagcgccagg ccggtcgacg
     5881 tgcggtacat cgggagaccg gcaaacttcg ccagatccac ttcgatatcc gccgccacaa
     5941 tcactaaatc cgcttccgcc acctcttccg gggtgatggc attgccggcc cccacggagc
     6001 cgcgcgtttc gacttttacc caccagccgc gttttttcgc ttctgtttca atggcttcag
     6061 ccgccataaa agtatgggcg acgccggtcg ggcaggccgt taccgcgacc acgcgtttcg
     6121 gaccgccgct cgctgcagga gcagccgcag caggggcgct gtaaggggtc gcatggcttt
     6181 tggcttcact cagaaacagt tccggatgcg cgacggcgcg accaatatcc cccagccaaa
     6241 cctttttgcc gttcaaagca ttgtcgttcg gcagagattc gcccagcacg atcgccagtt
     6301 cagcatcatt cggattgtcg ataatttcca gatttgcttt atgcgccgcc gctccaagca
     6361 gggttttcgc catgtaagcg cgagcctggc cgagattagc gtcaattatc agcagcgttt
     6421 tcattatgcc tctcctgctg tcagttaaac ggttgtaagt cgacacgcgc catcattgcg
     6481 gccaactgag gacgatcggt aatacccaca ttgctctggc tgaccgccag cgcggcaacc
     6541 gccgtcgcca gacgcagcgt atgttcgctg gactcgcgca tcagcaggcc gtaaatcaat
     6601 ccgccaacca tggaatcgcc tgcgccgacg gtacttacca cgtcaaccgc cggtggttta
     6661 gcgatccatt ctcctgaggc gttaacccac agcgcgcctt ccgcccccag cgaaatcacc
     6721 acatgagcga taccctgttc gcgtaacgcg tgcgccgcat caatcacatc tttcatttcc
     6781 gggagcttac gacccgccca aatttccagt tcgcggcgat tcggtttcac cagccacggc
     6841 gcagctttaa gaccggcgac taacgcttca cggctactat caaagataat gcatggacac
     6901 tggctgcgca gacgcgtcat ccagtcggtg aacgcttccg gactcacgcc agccggtaag
     6961 ctaccgctga cgcagaccat atcgaactga cccagccagc tcagggagtc gttaacaaag
     7021 cgttcccagt ctgcgggagt cacgtcaaag ccggaaaagt tgaagtcggt cacttcgcca
     7081 tctttttccg tcagcttcac gttgatgcgg gtccggccct gaaccacctg aaagcggtta
     7141 gcgataccca gttcgctgaa taattgctga aaaccgtcct ggttatcttt accgagaaaa
     7201 ccgccgacag tgacgtcgat gcctaagtct ttcagcactt tggcaacgtt aatgcctttg
     7261 cccgccgcgt gcagacccgt ggttttcacc aggttcactt cgccgcgttc gatttcaggg
     7321 caaaacccaa ccagatcgta agccggatta agggtaatgg tggcgacacg cctgctcatt
     7381 atgcgccctc cccaagaccg gcggcgatcg catcgccaat cgctttcagc gcctgttcag
     7441 catcttcacc ctgcgcggta aagcgcagac gatggccttt cttcacgcct aatgccacca
     7501 ctttcatcag actacgtccg tttgccggtt tgccggttcc atcaaggttt gtcacggtaa
     7561 tttcactgtt aaattgttta atcgtattca ccagcatggt gcccggacgg gcatggagac
     7621 catgctcatt acgcactaca aattccgcgc tcagtacgtc atccgtcagc gcatcatcac
     7681 tggtcagcaa cgccagcagc gtcgcggcgt cagcgctcag cagacgatcg gctttattgt
     7741 tcagcaacag gtcgccgagg cgttttagca cggcaatcgg ctgctcgtcg ttcatcgcga
     7801 cagtgactaa taaggctgct ttttcaccct ctacgtcaaa cgcctgggtc gcgcggctta
     7861 ccgcaacagc actgcgcaaa ttgccttccg cgctgtcgtt cagccagatg ccttgtccca
     7921 gattcatcgg actatcgtta atcgtttttg cgacgaacgc cgcatcaacc gctcccgcct
     7981 ctttcagacg cgccgcattt agcgcctgca atgtgaccag cgagctggcg atgacatcca
     8041 gcgtcatcgt ctcgttatca agttttaatt gttcactttg cttctcgccc atcagcaatg
     8101 cgcgcagctc ttccgccgtt gtcgcggatt tcagctgttc agccacggag tcatcgctca
     8161 gcacatgcgt cagctgacgc agcaggccaa ggtgttcgtc cgaactggcg gcaataccaa
     8221 tcgccacgta ggcgacctgg ccttctcccc aggtaacgcc ctgcggaaat tgaaagacct
     8281 ggacgccggt tttcagcacc tgatcgcgcg tgtctgttgt accatgggga atcgcaatac
     8341 cattgccaag aaaggttgag gtttgctgtt cgcgcgccag cataccgtca acatagccgc
     8401 ccgccacatt ccccgcctgc gctaacgcag cggcgatttg ccgaatggcc tcttctttat
     8461 ttccggcctg ctcgcccgga tgaatgtcct gaaccgataa ctggaacatg tgtctcctct
     8521 cctgctgaat tgaaacgatt cagccactat gagaaaaaaa gcgccaatct gagttatcaa
     8581 aaaaaccaga tcgcgctgaa acgtttcaag aaagtctgga tctttctgct tcagcacgca
     8641 agaaaagtta ccggttttgt agcaattttt tgaggtgaag cacatttttt ctccaacaga
     8701 ccctcaatag ctgacgcata aaaggcttca gcttttttct ttcagcttgc gtcagcacgc
     8761 ccttgtaaca aactggaatg ctattttgat ttttcgtgtc gattttgatt cagacgcctg
     8821 tttattttct gacgggcagc gtaaactccg cctctcttca caccactgat atagaaacat
     8881 gcacaacagt cccgccgccg ctgcgcccaa atcgtttgac ctgacgtcta ccgccttttt
     8941 gatcgtcgct tttctcaccg gtattgctgg tgcgttacag acgccgacac tcagtatttt
     9001 tctgacggat gaggttcacg cccgtcccgg catggtgggt ttctttttta ccggcagcgc
     9061 ggttatcggc attatcgtga gccagtttct ggcgggtcgc tcagataaaa aaggcgatcg
     9121 caaaaaactg atcgttttct gttgcgtgct gggcatgttg gcctgcgtgt tgtttgcctg
     9181 gaaccgcaac tactttattt tgctgttcat cggcgtcttt ctcagtagct tcggctctac
     9241 cgccaacccg cagatgtttg cgctggcccg agaacatgcc gatcgtacag gtcgtgaagc
     9301 ggtgatgttc agctcaatcc tccgcgccca ggtctcgttg gcctgggtca ttgggccgcc
     9361 gctggcctat gcgctggcga tgggttttag ctttacggtg atgtatttga gcgcggcggt
     9421 agcttttatc gtctgcggcg tcatggtgtg gttcttttta ccgtcaatgc gcaaagatgc
     9481 gccgctggca accggcacgc tggaagcacc gcgtcgtaat cgccgcgata cgctgttgct
     9541 gtttgtcatc tgtacgttaa tgtgggggac taacagcctg tatatcatta atatgccgct
     9601 gtttatcatc aatgagctgc atcttccgga aaaacttgca ggcgtgatga tgggcaccgc
     9661 cgccgggctg gagattccca caatgctgat tgcaggttac ttcgccaaac ggttgggaaa
     9721 acgcctgtta atgtgcatcg ccgttgtcgc cggactgtgc ttttatgcgg ggatgttgct
     9781 ggcgcacgca ccggcaacgt tgctcggctt gcagttgctg aacgcgattt acatcggcat
     9841 tcttggcggg attggcatgc tctattttca ggatctcatg ccaggccagg cgggttcagc
     9901 caccacgctg tataccaata ccattcgcgt cggctggatc attgccggtt cgttggcggg
     9961 aatcgccgca gaaatctgga attatcatgc ggtcttctgg tttgcgttag ttatgattgt
    10021 cgccaccatg ttctgcctgg cgcgtattaa agatgtttaa cttgcaagcc tgatactttt
    10081 actcttcgac acatttcagc gcagaattta tttctgcgcg atgttcatgc gcggtcattc
    10141 attgtctttt tctcaatacg atattctgtt agcgccctct tacataagag accggttatt
    10201 gagaaaatta cgcccatcag cccgcaaagg accaacacca gccgcatctt atattttggt
    10261 gtaacagcaa catctatcac ttcaatgtta gcattatttt taaccgcctc cgacaacaag
    10321 gatagctttg tatatgtttc cgtttgtaac atatttttat gcacgctata acgtttaatg
    10381 tcaccatcat cgatatacca tgctgccatt ttatcgacgc tatttttcag ggtggaaata
    10441 atattattga cgctttcttc cctcccctgc gccttaaaaa ggacaagctg atttttcgcg
    10501 tcaaaactta ttttattttt atattccgca ggcaagaaac ggctaaactg gttaaggata
    10561 accgttgttt tacattgaat atcattagca tagccacata acgcataggt agcaggcgta
    10621 tccagattag gtttgattgt aatactcaca acctttgtat catgatgcac gctcacaaaa
    10681 acatagccaa tggcgacaaa aataaaggta gcgatcacga tacttagcca ttttcttata
    10741 aggaataagg aaacgtcgac taaatcaatt tcactatttt ctccccgcat ttcacatccc
    10801 ttttaaaacg ctaatagtca acccgaatac tgaaataaca aaaagcaaca ccagcgtaaa
    10861 aataaacgcc ctggct
//
LOCUS       DAJVBX010000165        10795 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.165, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000165 DAJVBX010000000
VERSION     DAJVBX010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 10795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10795
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.165"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(82..588)
                     /gene="tpx"
                     /locus_tag="OPV72_003496"
     CDS             complement(82..588)
                     /gene="tpx"
                     /locus_tag="OPV72_003496"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HCR9915699.1"
                     /translation="MSQTVHFQDNPVTVANVIPQAGSKAQAFTLVAKDLSDVSLSQYA
                     GKRKVLNIFPSIDTGVCAASVRKFNQLATEVENTVVLCVSADLPFAQSRFCGAEGLSN
                     VITLSTLRNNEFLKNYGVEIVDGPLKGLAARAVIVLDENDNVIFSQLVDEITHEPDYD
                     AALNVLKA"
     gene            704..1669
                     /gene="ycjG"
                     /locus_tag="OPV72_003497"
     CDS             704..1669
                     /gene="ycjG"
                     /locus_tag="OPV72_003497"
                     /EC_number="5.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-Ala-D/L-Glu epimerase"
                     /protein_id="HCR9915700.1"
                     /translation="MRSVKVYEETWPLHTPFVIARGSRSEAHVVVVELEEEGVKGIGE
                     CTPYPRYGESDASVMAQIMSIVPQLENGLTREALQKLLPAGAARNAVDSALWDLQARQ
                     RQQSLAGLLGVTPSPVFTTAQTVVIGTPEQMAASAAALWKKGATLLKIKLDARLISER
                     MVAIRSAVPEATLIVDANESWRPEGLAARCQLLADLNVAMLEQPLPAQDDAALENFIH
                     PLPICADESCHTRSSLKALTGRYDMINIKLDKTGGLTEALALATEAREQGFGLMLGCM
                     LCTSRAISAALPLMPQVSFADLDGPTWLAVDVEPALRFTTGQLHL"
     gene            complement(1644..2372)
                     /gene="mpaA"
                     /locus_tag="OPV72_003498"
     CDS             complement(1644..2372)
                     /gene="mpaA"
                     /locus_tag="OPV72_003498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein tripeptide amidase MpaA"
                     /protein_id="HCR9915701.1"
                     /translation="MTVTRPRAERGAFPPGTEHYGRSLLGAPLIWFPAPAVNRESGLI
                     LAGTHGDETSSVVTLSCALRTLNPSLRRHHVVLAVNPDGCQLGLRANANGIDLNRNFP
                     AANWKAGETVYRWNSRAQERDVVLLTGDHPGSEPETQALCQLIHRLQPAWVVSFHDPL
                     ACIEDPRRSELGEWLADAFALPLVTSVGYETPGSFGSWCADLNLHCITAEFPPVSADE
                     ASEKYLLAMSNLLRWHPKDGVDPS"
     gene            2562..4175
                     /locus_tag="OPV72_003499"
     CDS             2562..4175
                     /locus_tag="OPV72_003499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HCR9915702.1"
                     /translation="MRHSVSVTCCALLVSSFSLAYAADVPGGTVLAEKQELVRHIKDE
                     PASLDPAKAVGLPEIQVIRDLFEGLVNQNEKGEIIPGVASQWKSNDNRIWTFTLRDDA
                     QWADGTPVTAQDFVYSWQRLVDPKTLSPFAWFAALAGITNAQAIIDSKVTPDQLGVSA
                     VDAHTLRVQLDKPLPWFASLTASFAFYPVQKANVESGKDWMKPGKLIGNGAYVLKERV
                     VNEKLVVVPNTHYWDNAKTVLQKVTFLPINQESAATKRYLAGDIDITESFPKNMYQKL
                     LKDIPGQVYTPPQLGTYYYAFNTQKGPTADSRVRLALSMTIDRRLMAEKVLGTGEKPA
                     WHFTPDVTAGFKPDPSPFEQMSQEELNAQAKTLLRAAGYGSQKPLKLTLLYNTSENHQ
                     KIAIAVASMWKKNLGMDVKLQNQEWKTYIDSRNTSNFDVIRVSWVGDYNEPSTFLSLL
                     TSTHTGNISRFTNPTYDKILTQATMENTAEARNADYNAAEKILTEQAPIAPIYQYTNG
                     RLIKPWVKGYPITNPEDVAYSRTMYIVKH"
     gene            complement(4272..5201)
                     /locus_tag="OPV72_003500"
     CDS             complement(4272..5201)
                     /locus_tag="OPV72_003500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic alcohol reductase"
                     /protein_id="HCR9915703.1"
                     /translation="MKQSNNQVGEKVLVLGAGQLGASVLASLVPAITQRNGSVCVIVS
                     GRSRDKQSKRRSSIHQQLADAGARFIPVDIADSSVAALKDQFHGFDTIINCMGFVAGA
                     GTQIKITRAVLEAGVKRYFPWQFGVNYDVVGKGSGQPVWDEQYDVRTLLREQNVTEWV
                     IVSTGLFTSFLFEPAFDVVNLDQKTINALGGWERQVTVTSPADIGRLTTEIYLHQPRI
                     TNEVVFVAGETTSYAKLAKTVERVTQQTFTRGVLTLPDLQEQLRLHPHDPMLRYRVAF
                     ARGDGMWWPMSDTWNAQHHLPTQDIATWLKTQQ"
     gene            5320..6225
                     /locus_tag="OPV72_003501"
     CDS             5320..6225
                     /locus_tag="OPV72_003501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCR9915704.1"
                     /translation="MDKLEAMQVYVCVVDTHSFIRAAEVLGVPRSTVSRVVKELESWL
                     KIQLLQRTTRKLSVTAEGRRYYEECKRVLADIAAMESSFPGRAAQPKGRFKVGMPQSL
                     ARHCIIPTLPAFLCQYPELELILCSSDSVEDIILQGYDCVIRAGRIDDSTTLVARPLA
                     SFNWVIAASPTYIERYGSPENLDDLQKHHAVGYLNHRTGRTTDWFFTREGEDYAMRVQ
                     ETLVVDDTDAYIQAGIQGLGLIRVASYLVAPYLHSGALVTCMDNHFYDLPLALVYPQN
                     RFLSPAVRAFYDWCKTALSQPEPLR"
     gene            6502..7371
                     /locus_tag="OPV72_003502"
     CDS             6502..7371
                     /locus_tag="OPV72_003502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HCR9915705.1"
                     /translation="MEYSILSNNLKMPMVGFGVFKVTDKEECQQSVLSAIRSGYRLID
                     TAAVYGNEDAVGDAVREAIATGLCTREELFITSKLWVQDMANYDLAKAGIEASLKKSG
                     LDYFDLYLLHQAMGDYFSAWRALEDAYEAGKLKAIGVSNFYAHVLANFCETVRITPMV
                     NQVELHPYFAQPAALETMKHYNVQPEAWAPLGGGRHKPYENVMLQRIADAHQKTIAQV
                     VLRWNVQRGVTVIPKSTRQERIEENFAIWDFSLTDNEMAQINALDLGYVGEAVKHFNP
                     EFVRGCLGVKIHD"
     gene            complement(7462..8175)
                     /gene="bdcA"
                     /locus_tag="OPV72_003503"
     CDS             complement(7462..8175)
                     /gene="bdcA"
                     /locus_tag="OPV72_003503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCR9915706.1"
                     /translation="MMLFRNKSVLVLGGSRGIGAAIVRRFSADGASVVFSYAGSREAA
                     EKLAAETGSTAIQTDSADRDAVISLVREYGPLDILVVNAGVALFGDALEQDSDAIDRL
                     FRINIHAPYHASVEAARNMPEGGRIIIIGSVNGDRMPIPGMAAYAASKSALQGLARGL
                     ARDFGPRGITINVVQPGPIDTDINPEDGPMKELMHSFMAIKRHGRPEEVAGMVAWLAG
                     PEASFVTGAMHTIDGAFGA"
     gene            8253..8843
                     /locus_tag="OPV72_003504"
     CDS             8253..8843
                     /locus_tag="OPV72_003504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCR9915707.1"
                     /translation="MTTKHSRTPGRPRQFDPEQSIETAQHLFHSRGYDAVSVADLTKA
                     FGINPPSFYAAFGSKLGLYTRVLKRYRMTDAIPLGALLRHDRPTAKCLIDVLMEAARR
                     YAADPDATGCLVLEGAHCNDKPAREAACEFYIAAENLIRTYVAMRYPQEADRTTDFMG
                     TLMAGLSAKARAGYSLERLQESVLLAGDVLERLLPD"
     gene            8972..9208
                     /locus_tag="OPV72_003505"
     CDS             8972..9208
                     /locus_tag="OPV72_003505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgdI/YgdR family lipoprotein"
                     /protein_id="HCR9915708.1"
                     /translation="MQKCSLITVLSLSVLMLAGCTTTYTMTTRTGEIIETQGKPEVDT
                     ATGMTKYADVYGYHRVIKTSEIVQTTEGASKLDW"
     gene            complement(9422..10531)
                     /locus_tag="OPV72_003506"
     CDS             complement(9422..10531)
                     /locus_tag="OPV72_003506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_448089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915709.1"
                     /translation="MYIIRGDIIHIFEIRADDMYTTIRNTTLAMVACFSYIAHASTHP
                     PLIITRGAGGDASGAAVIHDNWRHGTPDLVNLTDIPIDKIRPEKYRCVLIIGQGAIKE
                     MLLANNASAILSGKTVGLYTHLIDQNTLRLLRQLQNKVRFNLFFTRSQITLLKLRNIS
                     EYNFLSSKVNNVWGQDSLAIETVAPDRGNIPEKALPLKTTDYVIWLGGNYTTSSGTQR
                     IFTNDQIVVALKPLHNVISPNASIAIMLSPRFFDNSMSKEAKVKRLKAVLNTFSQNRV
                     TFYMSKEMLANLKEFDLPVQLSPSYAELMRMPWASATRHFASVDQYNLFADLIPKVTP
                     FLLEPNDADQALYATDYLNTRRVSLTQNILNHGCD"
BASE COUNT         2688 a         2588 c         2867 g         2652 t
ORIGIN      
        1 aaggcctccg gatagaggcc ttcttgtgac aaaagagcac cgcctgtagc actgacaaac
       61 gtagcgccag caggcgctgg cttatgcctt caggacatta agcgcggcgt cgtaatcggg
      121 ctcgtgggtg atttcatcca ccaactggct gaaaataacg ttgtcgtttt cgtcaagcac
      181 gatgactgcg cgcgccgcca aacctttcag cgggccgtca acgatttcga cgccgtagtt
      241 ttttagaaac tcgttattac gcagagtgga aagcgtaata acgttgctca ggccttccgc
      301 gccgcaaaaa cgcgactgtg caaaaggcag gtcagcagaa acgcacaata cgacggtatt
      361 ctccacttct gtggccagtt gattaaactt acgaactgat gcggcgcata cgccagtatc
      421 aatgcttggg aaaatattca gcactttgcg tttgcctgca tattggctga gggaaacgtc
      481 agacaaatct tttgcgacaa gagtaaaagc ctgtgctttg ctaccagcct gcggaataac
      541 gttggcaacg gtgaccgggt tatcctggaa atgtacagtc tgtgacataa ttatgttcct
      601 atttacttat agttaacgtc gaaatccagt ttaagtcatt attcattaac acggcaaata
      661 ctatttgtag caagccgcgt ccggcgctat cagaggggaa gagatgagat ctgttaaggt
      721 atatgaggaa acctggccgt tacatacgcc ttttgttatt gcgcgtggta gccgaagcga
      781 agcgcatgtt gtcgttgtcg aactggaaga agagggcgta aaaggcatcg gggaatgtac
      841 gccatatcca cgttatggtg aaagtgatgc ctcggtcatg gcgcaaatca tgagtattgt
      901 gcctcagttg gaaaacgggc tgactcgcga agcattgcag aaactgttgc cggcaggcgc
      961 ggcgcgcaac gcggtggata gcgccttatg ggatttgcag gcccgccagc ggcagcaaag
     1021 ccttgccggg ctgctcggcg tgacgccgtc cccggttttt actaccgcgc aaacggtagt
     1081 gataggcacg ccggaacaga tggctgccag tgcggcggca ctatggaaaa aaggggcgac
     1141 gttgctgaaa attaaactcg atgctcgtct gattagcgaa cgtatggtgg cgatccgctc
     1201 ggcggtgccg gaggcgacgc tcattgtgga cgccaatgaa tcgtggcgcc cagaagggct
     1261 ggcggcgcgt tgccagttac tggcggatct gaatgtcgcg atgctggagc aaccgctgcc
     1321 cgcgcaggat gacgccgccc tggaaaattt tattcatccg ttgcccatct gtgcagatga
     1381 gagctgccat actcgcagta gtctgaaagc cctgacgggg cgctacgata tgatcaacat
     1441 taagctggat aaaaccggcg gtctgactga ggcgctggcg ctggcaacgg aggcgcggga
     1501 gcaaggattc ggcctgatgc tgggctgtat gctctgtaca tcaagagcga ttagcgccgc
     1561 gctgccgctt atgccgcagg tgagcttcgc cgatcttgat ggcccaacat ggctggcggt
     1621 tgatgttgag cctgcgctac gctttacgac gggtcaactc catctttagg atgccagcgg
     1681 agcagattcg acatcgccag caagtatttt tcgctggctt catcggcgga aacaggggga
     1741 aactcggcgg taatgcagtg caggttgagg tcggcgcacc agctgccaaa cgaaccgggc
     1801 gtttcgtaac ctacgctggt caccagcggc aacgcaaacg catcggccag ccactcgcct
     1861 agctcgctgc gacgtggatc ttcaatgcag gctagcggat cgtgaaaaga gacgacccag
     1921 gcgggttgga gtcgatgaat taactggcaa agcgcctggg tttccggttc tgagccggga
     1981 tggtcgccgg ttagcagcac gacatcacgc tcttgcgcgc ggctattcca gcgataaact
     2041 gtctcacccg ctttccagtt ggcggcggga aagttacggt ttagatcaat gccattcgca
     2101 tttgccctta accccagttg acagccatca ggattaacgg caagtacgac atgatgacgg
     2161 cgaagggacg gatttaaggt gcgtaacgca caggagagcg tcaccacgga tgaggtttca
     2221 tccccgtggg tgccagccag tatcaggccg ctttcgcgat tgacggcagg cgccggaaac
     2281 cagattagcg gcgcgcctag tagcgaacgt ccataatgtt cagtgcctgg cggaaatgcg
     2341 ccgcgctcgg cacgggggcg ggtgacagtc atacgcgttt cccgaagctg agaccagtag
     2401 ggtaatcatc gtagtgttgt gtaaaacccg ccgattatca aatggtttct atttaccctc
     2461 ttgtatggcg cgatatcaac tttctggcgg aagataattg catttctttc tgctgaaaca
     2521 aataattacg ttgtcattta actcatcttt gaggaacttc tatgaggcat tctgtttcag
     2581 taacctgttg tgcgctgttg gttagcagct tttccctggc atatgctgcg gatgttcccg
     2641 gcggaacggt actggcagag aaacaagaac tggtgcgtca tatcaaagat gagcccgctt
     2701 cgttagatcc agcgaaagcc gttgggctgc ctgaaattca ggtgatccgc gatctgtttg
     2761 aagggctggt taaccagaac gaaaagggtg aaattatccc tggcgtcgcc agccagtgga
     2821 agagcaatga taatcgtatc tggacgttta cgttgcggga tgatgcgcaa tgggccgatg
     2881 gaacgccggt gaccgcccag gattttgtct atagctggca acgcctcgtt gatcccaaaa
     2941 cgctttcccc cttcgcctgg tttgccgctc tggctggcat cactaatgcg caagccatta
     3001 tcgacagtaa agtcacgccg gatcagcttg gcgtcagtgc cgtggacgcg cacactttgc
     3061 gtgttcagct tgacaagccg ttgccctggt ttgccagtct gaccgccagt tttgcctttt
     3121 atccggtcca aaaagcgaat gtcgaaagcg gcaaagactg gatgaagccg ggaaaactga
     3181 ttggcaatgg cgcgtatgtg cttaaagagc gcgtggtaaa tgaaaaactg gtggtcgtgc
     3241 ctaatacgca ttactgggat aacgcgaaaa cggtactgca aaaagtgaca tttttaccca
     3301 ttaaccagga gtcggctgcg acgaaacgct atcttgccgg tgatattgat atcaccgaat
     3361 ctttccctaa aaatatgtac cagaaattat tgaaggatat tccagggcaa gtttatacgc
     3421 cgccgcaatt agggacttat tattatgcgt ttaatacgca gaaagggccg acggcggatt
     3481 cccgcgttcg tctggcgcta agtatgacca ttgatcgccg tttgatggcg gaaaaagtct
     3541 taggtaccgg tgaaaaaccg gcctggcatt ttacaccgga tgtcacggca ggatttaagc
     3601 ccgatccttc accgtttgaa caaatgagtc aggaagaact taacgcccag gcgaaaacat
     3661 tgctgcgtgc agcaggctac ggatcgcaga agccgcttaa attaactctg ctttacaata
     3721 cctcagaaaa ccatcagaaa atcgcgattg cggtggcgtc aatgtggaag aaaaatctgg
     3781 ggatggatgt gaaattgcaa aaccaggagt ggaaaacgta tatcgacagc cggaatacca
     3841 gtaattttga tgttattcgc gtctcctggg tgggtgatta caacgaaccg tcgactttct
     3901 tatccttatt aacgtccacg catacgggga atatttcacg ctttactaat ccgacttatg
     3961 acaaaatcct gacgcaagcg acgatggaaa ataccgccga agcgcgtaac gcggattaca
     4021 atgcagcgga gaaaatttta acggaacaag cgcctatagc acctatttat cagtatacca
     4081 atggccggtt aattaaaccg tgggtaaagg gataccccat tactaacccg gaagatgtgg
     4141 cctatagccg tacaatgtat atcgtgaagc actgatgcgt actggtttct tgttaactca
     4201 aggtagccac gcccgccgcc tgatgctggc agaaggcatg gggattaagc gagcgcctga
     4261 tgccgccgtt ctcattgctg tgttttcagc caggtggcaa tatcctgtgt cggcagatga
     4321 tgttgtgcat tccaggtgtc actcatcggc caccacatac cgtcaccacg cgcgaaggcg
     4381 acgcgatagc gcagcattgg gtcatgcgga tgtaaacgga gttgctcctg taagtcaggt
     4441 agcgtcaata cacctcgggt aaaggtttgc tgcgtcacgc gttcgaccgt tttcgccagt
     4501 tttgcataag aggtcgtttc ccccgcaaca aagacgactt cgttagtgat acgcggctga
     4561 tgcagataaa tttcagtggt caggcgacca atatccgcag gcgacgtgac ggtgacctgc
     4621 ctttcccatc cgccgagggc attgatggtt ttttggtcta agttgaccac atcaaaggcc
     4681 ggttcgaaga gaaaagaggt aaataaaccg gttgaaacaa tcacccactc tgtgacgttt
     4741 tgctcgcgca aaagcgtcct gacgtcatac tgttcgtccc acaccggctg gccgctgcct
     4801 ttgccgacca catcgtaatt cacgccaaac tgccagggga aatagcgctt aacgcccgcc
     4861 tccagtaccg cgcgggtgat ttttatctgg gtacccgcac cggcgacaaa ccccatacaa
     4921 ttgatgatcg tatcaaaacc gtggaattga tcttttaacg ctgcaaccga actgtctgcg
     4981 atgtcgaccg ggataaaccg cgcaccggca tccgccagtt gttgatgaat gctggaacgt
     5041 cgtttgctct gtttatccct ggatcgccct gacacaataa cgcaaacgga accattacgc
     5101 tgtgtgatcg ccggaaccaa cgacgccagc actgacgccc ccagttgtcc cgcgcccagc
     5161 accaatactt tttcacccac ctgattattg gattgtttca tttgcgcctc tctgtgttga
     5221 ttcacctgta gatagagatt acgtcaggga tctgcgttcg ataagacgcc gaagacgggt
     5281 tagactgttc tgataaatgg gataattggc ggggggaaaa tggacaagct ggaagcgatg
     5341 caggtctatg tttgcgtagt ggatacccat agttttatca gagccgccga agtgcttggc
     5401 gtgccgcgct caacggtatc gcgagtggtt aaagaactgg aatcctggct taagattcaa
     5461 cttttgcaac gtacaacccg caaacttagc gtgaccgcag aggggcggcg ttactacgaa
     5521 gagtgcaaaa gagtgctggc agatatcgcg gccatggagt cgtcatttcc tggccgggcg
     5581 gcacaaccca aagggcgttt taaagtgggg atgccgcaat ctctcgcccg gcattgcatt
     5641 attcctacgc tcccggcctt tttgtgccag tatccggagc tggagctgat actttgttcc
     5701 agcgatagcg tggaggatat tatccttcaa gggtatgact gcgtgattcg ggccggcaga
     5761 atcgatgatt ccaccacgct ggttgcccgt ccacttgcca gctttaactg ggtgatagca
     5821 gcatcgccca cttacattga gcgttacggt agccctgaaa atttagatga tctgcaaaaa
     5881 caccatgcag tcggctacct gaaccaccgc accgggcgta ccaccgactg gttttttacg
     5941 cgtgaggggg aggattacgc gatgcgggtg caggagacgc tggttgtcga tgatacggac
     6001 gcttatattc aggccggaat acaggggctg gggttaattc gcgtcgccag ctatctggtt
     6061 gcgccgtatc tgcacagcgg ggcgctggtg acctgcatgg acaaccattt ttatgatttg
     6121 ccgcttgcgc tggtctatcc gcaaaacagg tttctgtcgc ctgcggtacg cgctttttat
     6181 gactggtgca aaacggcgct gagccagccg gagcctcttc gctaaaaaat attattccgg
     6241 atatcgcatt gcctgttcag aaaacttttt cacagacggt caaaatgacg gtactggttt
     6301 ttgacgcata agtaaaaggc attatcaaac aggtgctaca cggcgaggat atagcaagca
     6361 ctgaacgttt ggatgcaata aaaaatctgt acaactgtta ttaatgaact ttttgtataa
     6421 atataatcgg atttaacaat actcattgta cctgtatttt gctcttatca tggcgtcttt
     6481 acgacgaaag ggtgctttag cgtggaatat tcaatattaa gtaacaacct taaaatgcct
     6541 atggtgggtt ttggcgtttt taaggtaacc gacaaagaag aatgtcagca gtcagtgtta
     6601 agcgctattc gcagcggtta tcgtcttatc gataccgctg cggtatacgg caatgaagat
     6661 gccgttggtg acgctgttcg tgaagccatc gcgacaggtc tgtgtacccg tgaggagtta
     6721 tttattactt ctaaactgtg ggtgcaagat atggctaact acgatctggc caaagcaggt
     6781 attgaagcgt cgctgaaaaa atccgggtta gattattttg atctctattt attgcatcag
     6841 gcaatgggcg attattttag cgcgtggcgc gcgctggaag acgcttatga agccggtaaa
     6901 ctaaaagcca ttggcgtgtc caacttctat gcgcatgtgt tagccaactt ctgtgaaacc
     6961 gtcagaatta cgccaatggt aaaccaggtc gaattgcatc catactttgc acaacccgcc
     7021 gcgctggaaa ccatgaagca ttataacgtt cagcctgaag cgtgggcacc gttaggcggc
     7081 gggagacata aaccgtatga aaatgtcatg cttcaaagga ttgccgatgc ccatcaaaaa
     7141 accatcgcgc aggttgtcct gcgttggaac gtgcagcgtg gcgtcacggt tattcctaaa
     7201 tccactcgac aggaacgtat tgaagagaac tttgccatct gggatttctc actaacggat
     7261 aacgaaatgg ctcaaatcaa cgcccttgat ttaggctacg ttggcgaagc ggtgaagcat
     7321 tttaatcctg aatttgttcg cggttgtctt ggcgttaaaa tccacgattg atcccggcgc
     7381 ttgcggatgt tttctcgcat gaacagcttc taacacggtt gccggagcgt agacggcaac
     7441 cgtgtgatat tcgcctggcc gtcaggcgcc gaaggcacca tcgatggtgt gcatcgcgcc
     7501 ggtgacgaaa gaagcttccg gaccggcaag ccatgccacc attccagcca cttcttcagg
     7561 tcttccgtgt cgtttgattg ccatgaaact gtgcatcagc tctttcatgg ggccatcttc
     7621 cggattgatg tcggtatcaa tggggcctgg ctgcaccaca tttatcgtaa tcccgcgggg
     7681 gccaaaatca cgggccaggc cgcgcgccag cccttgcagg gctgatttac tggcagcgta
     7741 cgcggccatt cccggtatgg gcatccgatc gccattcacg gaaccgataa taataatgcg
     7801 tccaccttcc ggcatgttgc gggctgcttc gactgacgca tggtaaggcg catggatatt
     7861 aatacggaac aaacgatcta tcgcatcgct atcttgttcc agcgcatcgc cgaagagagc
     7921 cacgcccgca ttgacgacca gaatatccag tggtccgtac tcacgcacga ggctgatgac
     7981 ggcatcccga tcggcgctat ccgtctggat ggcggtgctt ccggtttccg ctgccagttt
     8041 ttcggcggct tcacgcgatc cggcgtagct gaaaacgacc gatgcgccgt cagcgctaaa
     8101 gcgtcgtaca atagccgcgc cgataccacg acttccccct aaaaccagta cagatttgtt
     8161 gcgaaatagc atcatcagga tgtcctttat gatattgtag tagtcactac aatatgcgta
     8221 atgaaatcat gccgtcaagg agttatgtag taatgactac aaaacatagc cgaacgccgg
     8281 gtcgccctcg ccagttcgat ccggagcaat ccattgaaac cgctcaacac ttatttcatt
     8341 cgcgcggata cgacgcggtg agcgtagcgg atctgacaaa agcgttcggg atcaatcctc
     8401 ccagtttcta tgcggcgttt ggcagcaagc tggggctgta tactcgcgta ttaaagcgtt
     8461 acaggatgac cgacgcgatt ccgctcgggg cgcttctgcg tcacgatcgc ccgaccgcga
     8521 agtgtcttat cgatgtgctg atggaagcgg caagacgtta cgctgccgat cctgatgcca
     8581 ccggatgtct ggttctggag ggcgctcatt gtaacgataa accggcacga gaggccgcct
     8641 gcgagtttta catcgctgct gaaaacctga ttcgcactta tgtcgccatg cggtatccgc
     8701 aagaggctga ccggacgacg gactttatgg ggacgctaat ggcgggactt tccgccaagg
     8761 cgcgagcggg gtatagcctg gagcgtcttc aggagagcgt gcttctggct ggggatgtgc
     8821 tggagcgatt actgccggat taacgcagcg catcaaaaaa cctgagccag tcagatacgg
     8881 acaaacaggg agcaatagcc ctaatcatcc atcttgccgt tgcggtattc ggtaaagtac
     8941 atcaaaaata gaggtgtcag ggaaacaaga aatgcaaaag tgtagtctta ttacggtact
     9001 tagcttatca gtgttgatgc tagccggatg tacaacgacc tataccatga cgacccggac
     9061 gggagagatt attgaaacgc agggtaagcc ggaggttgac accgcaaccg gaatgacgaa
     9121 atacgctgat gtttatggtt atcatcgcgt tattaaaacc agtgaaatag tgcagacgac
     9181 agaaggcgca tcgaagctgg actggtaatg cgctaaagca gttgggaggc cgtgtccagt
     9241 atgggtaccg gactgtttct gggcctgaat tgaatagagc gcctgtatag ccgaattccg
     9301 ggtctcggct tgatttgtgt tgtcagttat ttggttgttc cctgtatagt gaagataaac
     9361 agtactcatg gctaacggtc tgttttggat tgctaactat cccggattct gcgcgtttta
     9421 tttagtcaca accatggtta agaatatttt gggtcagact tacacgccgg gtattaagat
     9481 aatccgtcgc atagagagct tgatcggcat cattcggttc aagaagaaac ggcgtgactt
     9541 taggtatgag atcagcaaac aggttatatt gatccacaga ggcaaaatgc cgggtagcgc
     9601 tggcccaggg cattcgcatc agctctgcgt aagaagggga tagttgaaca ggcaaatcaa
     9661 attctttcag attagcaagc atctccttac tcatataaaa tgtgacccta ttttgcgaaa
     9721 aggtgttaag cactgccttc agtcgtttaa cttttgcttc tttactcatg ctattatcaa
     9781 aaaaacgtgg tgaaagcata atagcaatcg atgcatttgg tgaaataaca ttatgtagtg
     9841 gtttcagggc tacaacaatc tgatcgtttg tgaagatacg ctgcgtacca gaagaggtag
     9901 tatagtttcc acccagccag atcacataat ccgttgtttt gaggggaagc gctttttccg
     9961 gtatattacc cctgtcaggt gccactgttt caattgctag tgagtcttgt ccccagacat
    10021 tatttacttt agaactcaaa aaattatatt ctgaaatgtt ccttagtttt agtagagtta
    10081 tctgcgagcg ggtaaaaaag agattgaatc tcactttgtt ctgcaattgc cgaagtaatc
    10141 tgagcgtgtt ctgatcgatc agatgagtat aaagaccaac agtttttccg gaaagtattg
    10201 ctgaggcatt gttcgcaaga agcatctctt ttatagctcc ttgcccaata atcagtacac
    10261 aacggtattt ttctggtctg attttatcta tggggatatc ggtaagattg accaggtcag
    10321 gagtgccatg ccgccaatta tcatgaatga ctgcggctcc ggaggcgtct cctccggctc
    10381 ccctggtgat aataagagga gggtgggtac tggcatgtgc gatatacgaa aaacaagcta
    10441 ccattgctag cgttgtgttt ctgatggttg tatacatatc gtctgccctg atttcgaaaa
    10501 tatgaataat gtctcctctt ataatgtaca tcaaaaagag aacatttaaa ttaaacggta
    10561 tctcaacgag ataaaaggtt agcacagtaa agtatagaga gaatgtaatc ataccaacat
    10621 tgtaaatgtg ggagcatgaa ggccccgcaa gccgcccggc cagcatactc ccattaatag
    10681 ttaaagtatg gactttgctt ttaccgtaaa ctgtagccaa tattacctga tcactacacc
    10741 gtacagtact gtcagaaatc tgtccccggt gtcgcgtgca cgcaatttat ttttt
//
LOCUS       DAJVBX010000166        10793 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.166, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000166 DAJVBX010000000
VERSION     DAJVBX010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 10793)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10793)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10793
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.166"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(48..1391)
                     /locus_tag="OPV72_003507"
     CDS             complement(48..1391)
                     /locus_tag="OPV72_003507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HCR9915710.1"
                     /translation="MLNSIFIIFCLIAVSAFFSISEISLAASRKIKLKLLADEGSINA
                     QRVLKMQENPGMFFTVVQIGLNAVAILGGIVGDAAFSPAFSALFSHYMSPELSEQLSF
                     ILSFSLVTGLFILFADLTPKRIGMIAPEAVALRIINPMRFCLFVFRPLVWLFNGMANN
                     IFRLFKIPMVRKDDITSDDIYAVVEAGALAGVLRKQEHELIENVFELESRTVPSSMTS
                     RESIIWFDLHEDEQSLKKKVAEHPHSKFLVCNEDIDHIIGYVDSKDLLNRVLANQSMA
                     LNSGVQIRNTLIVPDTLTLSEALESFKTAGEDFAVIMNEYALVVGIITLNDVMTTLMG
                     DLVGQGLEEQIVARDENSWLVDGGTPIDDVMRVLDIDEFPQSGNYETIGGFMMFMLRK
                     IPKRTDSVKFSGYKFEVVDIDNYRIDQLLVTRLDNKSNVPAPKLPDAQGKEDSAA"
     gene            complement(1581..2219)
                     /gene="msrA"
                     /locus_tag="OPV72_003508"
     CDS             complement(1581..2219)
                     /gene="msrA"
                     /locus_tag="OPV72_003508"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HCR9915711.1"
                     /translation="MSLFDKKHLVTQADALPGRNTPMPIATLHAVNEHSMTNVPAGME
                     IAYFAMGCFWGVERLFWQLPGVYSTAAGYAGGYTPNPTYREVCSGQTGHAEAVRIVYD
                     PAVIRYEQLLQTFWENHDPTQGMQQGNDHGTQYRSAIYPLTPEQNAAAHASRERFQSA
                     MAAAGDHRPITTEIAHATPFYYAEDEHQQYLHKNPYGYCGIGGIGVCLPPDA"
     gene            2432..4165
                     /gene="tamA"
                     /locus_tag="OPV72_003509"
     CDS             2432..4165
                     /gene="tamA"
                     /locus_tag="OPV72_003509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter assembly complex protein TamA"
                     /protein_id="HCR9915712.1"
                     /translation="MPHIRQLCWVSLLCLSSSAVAANVRLKVEGLSGELEKNVRAQLS
                     TIQSDEVTPDRRFRARVDDAIREGLKALGYYEPTIKFDLLPPPAKGRQVLIARVTPGQ
                     PVLIGGTEVILRGGARTDKDYLALLKTRPAIGTVLNQGDYDNFKKSLTSVSLRKGYFD
                     SEFIKSQLGIALGRHQAFWDIDYDSGERYRFGPVTFEGSQIRDEYLQNLLPFKEGDEY
                     ESKDLAELNRRLSATGWFNSVVVAPEFEKSRKTKILPLKGVVSPRTENTIETGVGYST
                     DVGPRVKASWKKPWMNSYGHSLTTSTSISAPEQVLDFSYKMPLLKNPLEQYYLVQGGF
                     KRTDLNDTEQDSTTLAVSRYWDLSSGWQRAINLRWSFDHFTQGNVTNTTMLFYPGVMI
                     SRTRSRGGLMPTWGDSQRYSVDYSNTAWGSDVDFSVLQAQNVWIRTLYDRHRFVMRAN
                     LGWIETGDFDKVPPDLRFFAGGDRSIRGYKYKSISPKDSDGNLKGASKLATGSLEYQY
                     NVTGKWWGAVFVDSGEAVSDIRRSDFKTGTGVGVRWASPVGPVKLDFAVPVGDKDEHG
                     LQFYIGLGPEL"
     gene            4162..7941
                     /gene="tamB"
                     /locus_tag="OPV72_003510"
     CDS             4162..7941
                     /gene="tamB"
                     /locus_tag="OPV72_003510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter assembly complex protein TamB"
                     /protein_id="HCR9915713.1"
                     /translation="MSLWKKISLGVLIFIVVLLASVAFLVGTTTGLHLVFGAANRWVP
                     GLDIGQVTGGWRDLSLKNIRYEQPGVAVNAGEIHLAVGLDCLWRSSLCVNDLALKDIN
                     VAIDSKKMPPSEPAQEEEESGPLNLSTPWPITLSRVALNNINIKIDDTTVSVLDFTYG
                     LAWQEKNLTLKPTRLQGLLIALPKVAEVAQEEVVEPKIEKPQPDEKPLGETLKDLFAK
                     PVMPEMTDVHLPLNLNIESFRGEQLRITGDTDLTVRTMLLKVSSIDGNMKLDTLDIDA
                     NQGTVKASGTAQLANNWPVDITLNSTLNIDPLKGEKIKLKVGGALREQLEVRVNLSGP
                     MDVALRAQTRLAEAGLPLNLEVVSQRIAWPLTGDTQFQADDLKLKLSGKMTDYTLSMR
                     TAVKGQDIPPATITLDAKGNERQINLDKLTVAALEGKTELKALVDWQQAISWRGELTL
                     NGINTAKEIPDWPAKLNGVMKTKGSLYGGTWQMDVPELKLTGNVKQNSVNVNGTLKGN
                     SYMQWTIPGLHLALGPNSADIKGELGVKELNLDAAIDAPGLDNALPGLGGMAKGIVKV
                     RGTVEAPQLLADITAHGLRWQELSIAQARIEGDIKSTDQIAGHLNVRVERISQPDVNI
                     NLVTLDAKGSEKQHQLQLRVQGEPVSGQLSLTGSFDREEARWKGTLSDTRFQTPVGPW
                     SLTRAIALDYRNKEQEISIGPHCWLNPNAELCIPQTIDAGAAGRALVNLNRFDLAMLK
                     PFMPDTTQASGVFSGKADVSWDTTQEGLPQGKVTLSGRNVKVTQTVNDAPLPVAFETL
                     NLSADLHNNRAELGWLIRLTNNGQFDGQVQVTDPQGRRNLGGNVNMRNLNLAMVNPVF
                     LRGEKAAGMLNARLRLGGDVQSPQLFGQLQLSALDIDGNFMPFEMQPSQLAMNFSGTR
                     STLAGIVRTQQGQINLNGNADWSQIDNWRARVTAKGSRVRITVPPMVRLDVSPDVVFD
                     ATPSLFTLDGRVDVPWARIVVHDLPESAVGVSSDVVMLNNDLQPETPQTASIPINSNL
                     TVHVGNNVRIDAFGLKARLTGDLKVAQDKQGLGLNGQINIPDGRFRAYGQDLLVRKGE
                     LLFSGPPDQPLLNIEAIRNPDATEDDVIAGVRVTGTADEPKAEIFSDPAMPQAEALSY
                     LLRGQGLDSNQSDSAAMTSMLIGLGVAQSGQVVGKIGETFGVSNLALDTQGVGDSSQV
                     VVSGYVLPGLQVKYGVGIFDSLATLTLRYRLMPKLYLEAVSGVDQALDLLYQFEF"
     gene            7944..8288
                     /locus_tag="OPV72_003511"
     CDS             7944..8288
                     /locus_tag="OPV72_003511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcyclotransferase"
                     /protein_id="HCR9915714.1"
                     /translation="MRIFVYGSLRQKQGNSHWMTNAQLLGDYRIDNYQLYSLGHYPGA
                     VPGNGAVYGEVYRIDNATLAELDALRTRGGEYARQLIQTPYGSAWMYVYQRPVDGLTL
                     IESGDWLDRNQP"
     gene            complement(8342..9550)
                     /locus_tag="OPV72_003512"
     CDS             complement(8342..9550)
                     /locus_tag="OPV72_003512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR9915715.1"
                     /translation="MTSMQKWLRIGATLMFGLFVAYLDRSNLSVTLPTITHDLNIDGA
                     TASIVLTIFLIGYAFSNIFGGVFTQRYDPKKIVILMVLIWSIATVFVGFTSSVYVILI
                     CRLVLGITEGIYWPQQSRFASDWFSDKERTQANSIIQYYGQFLALGLGFMILSPLDAA
                     FGWRNVFIITGMIGIVVVVPLYITMLKKQEEAPYYRAPAPTEKTKLTLESLGGTPFLL
                     LIFTYITQGMLFWGITLWIPMVVNSLGYTGFSKALVSSLPYLTAVILAIPISWISDKT
                     QKRVLIASLGLLIPGVMLFLLPFVDAPGFKITLITLAMGYYAASFTPNIWSIIQSNVK
                     PHAIGPASGIINGIGAGGGGTLAGLMVGYFYRTTGSYMQGFMVLGCIVILGGASLLIY
                     GRIRAHHARR"
     gene            complement(9547..10710)
                     /locus_tag="OPV72_003513"
     CDS             complement(9547..10710)
                     /locus_tag="OPV72_003513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallo-dependent hydrolase"
                     /protein_id="HCR9915716.1"
                     /translation="MMKNDILITGGHIIDPARNINEINKLRIINDIIVDADKYPVTSE
                     TRIIHADGMIVTPGLIDYHTHVFYDATEGGVRPDMYMPPNGVTTVVDAGSAGTANFDA
                     FYRTVICASKVRIKAFLTVSPPGQIWSQENYDPDNIDENKIHALFRQYRNVLQGLKLK
                     VQTEDIAEYGLKPLTESLRIANDLRCPVAIHSTHPVVPMKELVSLLRRGDIIAHAFHG
                     KGSTILTNEGAVLAEVRHARERGVIFDAANGRSHFSMNTARRAIANGFLPDIISSDLS
                     TITKLAWPVYALPWILSKYLALGVTLADVINACTHTPAVLMGMAAEIGTLAPGAFADI
                     AIFKLKNRHVEFADIHGETLTGTHVLVPQMTIKSGEILFRQIDFGTRPNGVEK"
BASE COUNT         2679 a         2652 c         2989 g         2473 t
ORIGIN      
        1 aaacggctcc tgaatcagga gccgttgatg tttctggcaa acggatttca ggccgcgctg
       61 tcttctttac cttgcgcatc gggcagtttc ggcgccggta cgttgctttt attgtcgaga
      121 cgcgtcacca gcaactgatc gatacggtag ttgtcgatat ccaccacttc aaatttgtag
      181 ccggaaaact tcaccgaatc agtacgtttt gggatcttgc gcagcataaa catcataaag
      241 ccgccaatgg tttcatagtt gccggattgc ggaaactcat cgatatccag cacgcgcatg
      301 acgtcgtcaa tcggcgtgcc gccgtcaacc agccaggaat tttcatcgcg cgccacaatt
      361 tgctcttcca gtccctggcc gaccaggtca cccattagcg tggtcatcac atcgttcagc
      421 gtaatgatac cgacgaccag cgcgtattca ttcataatga ccgcgaaatc ttcgcccgcc
      481 gttttgaaac tttccagcgc ctcagaaagg gtcagcgtat ccggcacaat caaggtattg
      541 cgaatttgca cgccgctatt cagcgccata ctttggttcg ccagcacgcg gttcagcaga
      601 tctttggaat ctacatagcc gatgatgtgg tcgatatctt cattacacac caaaaatttt
      661 gagtgcggat gttcggctac ctttttcttc aggctttgtt cgtcttcgtg tagatcaaac
      721 cagatgatac tttcgcgcga cgtcatagaa gacggtacgg tgcgggattc aagttcaaac
      781 acattttcaa tcagttcgtg ctcttgcttg cgcaagacgc ccgccagcgc gccggcttcc
      841 accaccgcgt aaatatcatc agaagtaatg tcgtctttcc gcaccattgg aattttgaac
      901 aggcggaaga tgttgtttgc catgccgtta aacagccaca ccagcgggcg aaaaacgaac
      961 aggcagaagc gcatcgggtt gatgatacgc aaagccacag cttctggcgc aatcataccg
     1021 atgcgtttcg gggttaaatc cgcgaacagg ataaacagcc ccgtcaccag cgagaaagag
     1081 agaataaagc tcaactgctc ggagagttct ggcgacatat agtgcgagaa aagggcggaa
     1141 aaggcgggcg aaaatgccgc atcgccgacg ataccgccaa gaatagcgac ggcgttcagg
     1201 ccaatttgca caacggtgaa aaacatgccg ggattttcct gcattttcaa tacgcgttgt
     1261 gcgttgatac tgccttcatc agctaataac ttaagtttaa tcttacgtga tgcggcaagc
     1321 gagatctcgg agatggagaa gaacgcactt acagcgatca ggcagaatat aatgaatata
     1381 ctgtttaaca tatcttatcc ggcgaaacgc cagatcctcg gaagggaagt ttataaatcc
     1441 gtgtggtaac gtttaatgaa aaccggctcg tagcagtgag ccgataagtt cagggctagt
     1501 atagcgtaag ctactgtaaa gtcgccagag ggttcatttt caactccgac aagttccccc
     1561 tacgcctgcg tcgtcacgcg tcacgcgtca ggcggcaggc aaacgccgat cccgccaatc
     1621 ccgcagtaac cgtatggatt tttgtgcaga tactgttggt gttcatcctc ggcgtagtaa
     1681 aacggcgtcg catgggcgat ttccgtggta atagggcgat ggtctccggc ggcggccatt
     1741 gccgactgaa agcgctcgcg actggcgtga gcggcggcat tctgttccgg cgttaaggga
     1801 taaatcgcag aacggtattg cgtaccgtga tcgttaccct gttgcatccc ctgcgtcgga
     1861 tcgtgatttt cccagaaggt ctgtaaaagc tgctcataac ggataacggc aggatcgtac
     1921 actatccgta ccgcttcggc atgaccggtc tgcccggagc agacttcccg gtaggttgga
     1981 ttaggcgtgt aaccgcccgc ataccctgct gcggtgctat atacgccggg caattgccag
     2041 aataaacgtt ctacgcccca gaaacagccc atcgcgaagt aggcgatctc catcccggca
     2101 gggacattgg tcatagagtg ttcatttacc gcatgcagag tggcgattgg catcggggtg
     2161 ttgcgtcctg gtaacgcatc tgcttgagta accagatgtt ttttatcaaa taaactcatg
     2221 aactattctc ccgaaagcgt taattggcgt taaggttgta acgagacgca tctttgcaca
     2281 caataacaac attaatgtat ctggatttaa ccataagaaa tatttgggca gtcgtctgct
     2341 tttcaatcga aattgttgat tttatgttaa gccgcggagc ggtagtgtga ttttttccag
     2401 gggtgggaat aggggatatt caggagaaaa tgtgccacat atccgtcagt tatgttgggt
     2461 tagcttactg tgcctgagca gttctgcggt agccgcaaat gttcgtctga aagtcgaagg
     2521 gctatccgga gagctggaaa aaaacgttcg cgcacagctc tctacgattc agagcgatga
     2581 ggtgacgccg gatcggcgct ttcgcgcccg agttgatgat gcgattcgcg aagggcttaa
     2641 agcgttaggc tattacgaac ccactatcaa attcgacttg cttccaccgc ctgcgaaagg
     2701 acggcaggta ttaatcgcca gggttacgcc cggccagccg gtgttgattg gcggtacaga
     2761 agtcatttta cgcggcggcg cgcgtacgga caaagattat ctggccttac tgaaaacgcg
     2821 tccggcaatc ggcacggtgc tcaaccaggg ggactatgac aattttaaaa agtcgttaac
     2881 cagcgtgtcg ctacgcaaag gctatttcga cagcgaattc attaaaagtc agttgggaat
     2941 tgctctgggc cgtcatcagg cgttttggga tattgattat gatagcggtg agcgctatcg
     3001 cttcgggcct gtcaccttcg aaggttcgca gattcgtgat gaatatttac aaaatctgtt
     3061 gccgtttaaa gagggtgatg agtacgaatc gaaagatttg gcggaactaa accgccggct
     3121 ttccgctacc ggatggttta attctgttgt ggtggcgccg gaatttgaga aatcgcgtaa
     3181 aacaaaaatt ctgccgttaa aaggcgtggt atcaccgcga accgaaaaca cgattgaaac
     3241 cggggtgggg tactccaccg acgtcgggcc gcgcgtgaaa gcgtcgtgga aaaaaccgtg
     3301 gatgaactcc tacggtcata gcctgaccac cagcaccagt atttctgcgc cggaacaggt
     3361 gctggatttt agttataaaa tgccgctgct gaaaaacccg ctggagcaat actatctggt
     3421 acagggcggt tttaaacgta ccgatttgaa tgatacggag caggactcga ccacgcttgc
     3481 cgtgtcgcgt tactgggacc tttccagcgg ttggcagcgg gcgattaacc tgcgctggag
     3541 tttcgaccac tttacccagg ggaacgtcac caataccacc atgctgttct acccgggcgt
     3601 gatgatcagc cgaacccgct cgcgaggggg actgatgcca acctggggcg attcgcagcg
     3661 ctactcggta gactattcga atacggcctg gggctccgac gtggatttct ccgtactgca
     3721 ggcgcaaaac gtctggattc ggactttgta cgatcgccac cgttttgtga tgcgcgccaa
     3781 tttgggctgg atagaaaccg gtgatttcga caaagttccg ccggatttac gtttcttcgc
     3841 cgggggcgac cgcagtattc gcggctataa atacaaatct atttcgccta aagatagcga
     3901 cggcaatctt aaaggcgcct caaaactggc aaccggatcg ctggagtacc agtataacgt
     3961 caccggcaaa tggtgggggg cggtgtttgt cgatagcggc gaggcggtta gtgatattcg
     4021 ccgtagcgat ttcaaaaccg ggaccggggt cggcgtgcgc tgggcgtcgc cggttgggcc
     4081 tgtcaaactc gattttgccg taccggtcgg cgacaaagac gaacacggtt tacagtttta
     4141 tatcggtctg gggcctgaat tatgagttta tggaagaaaa taagcctcgg cgtgttgatt
     4201 ttcattgtgg tgttactggc gagcgttgcg tttctggtcg ggacgacgac ggggctgcat
     4261 ctggtattcg gtgcggcgaa ccgctgggtg ccggggctgg atattgggca ggtcaccggc
     4321 ggctggcggg acttatcgtt aaaaaatatc cgctatgagc agccgggcgt tgcggtaaat
     4381 gcgggcgaaa ttcatctggc cgtcgggctt gattgcctgt ggcgcagtag cctgtgcgtc
     4441 aatgatctgg cgctaaaaga cattaatgtc gctatcgaca gcaaaaaaat gcctccttcc
     4501 gaaccggcgc aagaagagga agaaagcggg ccgctgaacc tctccacgcc ctggcccatc
     4561 acgctgtcgc gcgtggcgct gaataacatc aatatcaaga ttgatgacac taccgtttcg
     4621 gtgctggatt ttacctacgg gctggcatgg caggagaaaa acctgaccct gaaaccgacg
     4681 cggcttcagg gactgctgat cgcgctgccg aaggtcgctg aggtggcgca ggaagaggtg
     4741 gttgaaccca aaatcgagaa acctcaaccg gatgaaaagc cgcttggcga aacgctaaaa
     4801 gatctgtttg caaaaccggt aatgccggag atgaccgatg ttcacctgcc gctcaatctg
     4861 aatatcgagt catttcgcgg cgagcagcta cgcatcaccg gcgataccga tctgacggtg
     4921 cgcacgatgc tgcttaaagt cagcagtatc gacggtaata tgaagctgga tactctggat
     4981 atcgacgcca accagggcac ggtgaaagcc tccggtacgg cgcagctcgc caataactgg
     5041 ccggttgata ttacgctcaa cagtacgctg aatatcgatc cgctaaaggg tgaaaagatc
     5101 aaactcaagg tcggcggcgc gttacgcgaa caactggagg tcagggtgaa cctttccggg
     5161 ccgatggatg tcgcgcttcg cgcccagacg cggctggcgg aggccggttt accgctcaat
     5221 cttgaggtcg tcagccaacg cattgcctgg ccattgacgg gtgataccca gtttcaggct
     5281 gacgatctga agctcaaact gagcggtaag atgaccgact atacgttgtc gatgcgaacc
     5341 gccgtgaaag gacaagatat tccgccggcg accatcacgc tggatgctaa agggaatgag
     5401 cggcagatta atctcgataa actcaccgtc gccgctctgg agggaaaaac cgaactgaaa
     5461 gcgctggtgg actggcagca ggcgattagc tggcgtggcg aactgacgct gaatggcatc
     5521 aataccgcta aagagatccc ggactggccc gcgaaactta acggcgtcat gaaaaccaaa
     5581 ggcagcctct acggcggcac ctggcagatg gatgtcccgg agctcaagct gaccggtaat
     5641 gtgaagcaga acagcgttaa cgtcaacggg acgctaaagg gcaacagcta catgcagtgg
     5701 acgatcccgg ggctgcacct tgcgctgggc ccaaacagcg ccgatataaa aggcgagctt
     5761 ggcgttaagg agctgaatct tgacgccgcc atcgatgcgc cagggctgga taatgcgctg
     5821 ccagggctgg gcggcatggc aaaaggaatc gttaaagtcc gcggtacggt agaagcgccg
     5881 cagctgttgg cggatatcac cgcccacggt ctgcgctggc aggagctgtc tatcgcccag
     5941 gcgcgcatcg agggcgatat taaatccacc gatcagatag cgggccatct caacgttcgc
     6001 gtagagcgga tttcgcagcc cgacgttaac atcaatctgg tgacgcttga cgccaaaggc
     6061 agcgagaagc agcatcagct acagctccgt gttcagggag aaccggtatc cggtcaactc
     6121 tccctgacag gcagttttga tcgcgaggag gcgcgctgga aagggacgtt aagcgacacc
     6181 cgtttccaga cgccagtggg gccatggtcg ttgacccgcg cgattgcgct ggactaccgt
     6241 aataaagaac aggaaatcag tatcgggcca cattgttggc tgaacccgaa cgccgagctg
     6301 tgcatcccgc aaaccattga tgcgggcgcc gcaggacggg cgttggtcaa tctcaaccgc
     6361 tttgatctgg cgatgctgaa gccatttatg cctgatacca ctcaggccag cggggtcttt
     6421 agcgggaaag cggacgtgtc gtgggacacc acccaggagg gattgccgca ggggaaggtc
     6481 acactttccg gtcgtaacgt gaaggtcacg cagaccgtca atgacgcgcc gttaccggtc
     6541 gcgtttgaga cgctgaacct cagcgccgat ctgcacaata atcgcgccga gctgggatgg
     6601 ctgattcgcc tgacgaacaa tggtcaattc gatggccagg tgcaggtaac cgatcctcag
     6661 gggcggcgca atctcggcgg taacgtcaac atgcgcaatc tcaatctggc gatggtcaac
     6721 cctgtctttt tgcgcggcga aaaagcggcg ggaatgttaa acgccaggct acgtctgggc
     6781 ggcgatgtgc aaagcccgca gttgtttggt cagttgcagc ttagcgcgct ggatattgac
     6841 ggtaatttta tgccgtttga gatgcagccg agccagctcg ccatgaactt tagcggtacg
     6901 cgctcgacgc tcgctggtat cgtgcgaaca caacaagggc aaattaacct gaacggtaac
     6961 gccgactgga gccagattga caactggcgc gcgcgggtga cggcgaaagg cagtcgggtg
     7021 cggattaccg ttccgccgat ggtgcgcctg gatgtctcgc cggatgtggt ctttgacgcg
     7081 acgccttcgc tgttcacgtt ggatgggcgt gtggacgttc cgtgggcacg aattgtggtg
     7141 cacgacctgc cggagagcgc ggtcggcgtc tccagcgatg tggttatgct caataatgac
     7201 ctgcaaccag aaacgccgca gacagcatct attcccatca acagtaatct gacggtacat
     7261 gtcggcaaca acgtgcgcat cgacgccttc gggcttaaag cgcgtttgac cggcgatttg
     7321 aaagtcgcgc aggataagca ggggctgggg ctaaatggtc aaatcaatat tcctgacggc
     7381 cgattccgcg cctacggcca ggacctgctt gttcgtaaag gcgagctgct gttctccggc
     7441 ccgccggatc agccgctgct caatatcgaa gcgatccgta accctgacgc caccgaagac
     7501 gatgtcattg cgggcgtgcg cgtcacaggc acagctgatg aacccaaagc ggaaatcttc
     7561 tccgatccgg cgatgccgca ggctgaagcg ctttcttatc tgctgcgtgg gcaggggttg
     7621 gacagcaatc agagtgatag cgcagcaatg acttccatgc ttattggcct gggggttgcg
     7681 caaagtggtc aggttgtggg taaaatcgga gagacattcg gtgtaagtaa tctggcgctg
     7741 gacacgcaag gggtgggcga ttcgtcccag gttgtggtca gcggctatgt actgccgggt
     7801 ctacaggtga agtatggtgt agggatattt gactctctgg cgacgctcac gttacgttat
     7861 cgcctgatgc ctaagctata tctggaagca gtgtctggcg tagatcaggc acttgatttg
     7921 ctctatcagt ttgagtttta gcaatgcgaa tatttgtcta tggcagttta cgacagaaac
     7981 aaggcaacag tcactggatg accaatgccc aattgcttgg cgattaccgt atcgataact
     8041 accagttgta tagtctgggc cactatccag gcgcagttcc gggaaacgga gcggtatacg
     8101 gtgaagttta tcgaattgat aacgccacgc tggccgaact tgatgctttg cgcaccaggg
     8161 gcggtgaata cgcacgccag ttaatccaga cgccttacgg cagcgcatgg atgtatgtat
     8221 atcaacgtcc tgttgatggg ttaactctga ttgaaagcgg tgactggtta gacagaaacc
     8281 agccctgaac tgaacacgcc accctcgggt ggcgttgttt tttacattct ggctgatggc
     8341 gttaacgccg ggcatggtga gctcttattc tgccgtagat caataatgac gcgccgccca
     8401 ggataacaat gcatccgaga accataaatc cctgcatata gctgccggtt gtccggtaaa
     8461 aatagccgac cattaggcct gccaacgtac cgccgccgcc ggcgccgatg ccattaataa
     8521 taccggaggc tgggccaatc gcatggggtt taacgttcga ctggataatc gaccagatat
     8581 tgggggtaaa gctggcggca taataaccca tcgccagggt aatgagcgtg attttaaagc
     8641 ccggcgcatc gacaaatggc aggagaaata acatcacgcc ggggattagt aggcccagtg
     8701 aagcaataag tacacgtttt tgtgtcttat cactgatcca tgagatgggg attgccagta
     8761 taaccgcagt cagataaggc agagaactga ccaatgcttt actgaatccg gtatagccga
     8821 gagaattgac aaccatgggg atccataacg taattcccca gaacaacatc ccttgagtga
     8881 tgtaggtaaa aataaggagt aggaaggggg ttccgcccag cgattccaga gtaagtttag
     8941 ttttctctgt tggcgccggc gcacgataat aaggcgcttc ttcctgtttt ttcagcattg
     9001 ttatataaag tggaaccaca acaacaatgc cgatcatacc agtgataata aaaacatttc
     9061 gccaaccgaa ggcagcatcc agcggggaca aaatcataaa tcccaggcct aatgccagga
     9121 actgtccata atactggata atgctgttcg cctgcgtccg ttctttgtct gaaaaccagt
     9181 cgctggcgaa gcgggactgc tgcggccaat aaatgccttc ggtaatgcca agcaccagcc
     9241 gacaaatcaa aataacgtac actgacgagg taaatccgac aaaaacggtc gcaatcgacc
     9301 agattagcac catcagaatg actatttttt tcggatcgta tcgctgggta aatacgccgc
     9361 caaaaatatt tgaaaaggca tagccaataa gaaatatggt taatacaatg ctggccgttg
     9421 cgccatcaat attcaggtcg tgtgtaatcg taggtaacgt aacggaaaga ttagaacggt
     9481 caagataagc aacaaaaagg ccgaacatta atgtcgcgcc gatccgtagc catttttgca
     9541 ttgaggtcat ttttcaactc cgtttggccg cgtgccaaaa tcaatttgac gaaataatat
     9601 ctcaccggat tttatggtca tttgtggtac cagcacatgc gtccccgtga gcgtttcacc
     9661 atgaatatcg gcaaattcaa catgcctgtt ttttaattta aagatggcga tatcggcaaa
     9721 tgccccaggg gccagcgtac caatttctgc tgccataccc attaaaactg ctggggtatg
     9781 ggtacaggcg ttaatgacat cggcaagcgt gacgccgagt gctaaatatt tcgataaaat
     9841 ccatggtaag gcgtaaacag gccaggcgag tttagtgatg gttgagagat cgctactgat
     9901 gatatccgga agaaagccat tggcgatggc ccggcgtgcc gtgttcattg aaaaatggct
     9961 gcgaccattg gcggcatcaa atataacgcc tcgttctctt gcatgacgga cttcggctaa
    10021 gaccgcgcct tcattagtaa gaatggtgct acctttgccg tgaaacgcat gagcgataat
    10081 atcgccgcgg cgtagcaagg agacaagttc tttcatggga acgacgggat gagtcgagtg
    10141 tattgctacg gggcacctta aatcgttggc aatacgaagg gattcagtca gcggttttaa
    10201 gccatattca gcaatgtcct cagtctgaac cttgagtttt aatccctgaa gaacgttgcg
    10261 atactggcga aacagcgcgt ggatcttatt ttcatcaata ttgtcaggat cataattttc
    10321 ttgtgaccag atttggcccg gcggcgacac ggtcagaaac gctttgattc gaactttgct
    10381 ggcgcaaatc accgttcggt agaaggcatc aaagtttgcc gtaccggcag aacctgcatc
    10441 cacgacggtg gtgacgccat tcggcggcat gtacatatca ggcctgacgc cgccttccgt
    10501 cgcatcataa aaaacatgcg tgtgataatc gataagaccg ggagtgacga tcatgccgtc
    10561 ggcatggata atccgggtct ccgaagttac aggatattta tcggcatcaa cgataatatc
    10621 gttaatgatg cgtaacttgt taatctcatt aatattacga gcgggatcga tgatatgtcc
    10681 accggtaatt aatatatcat ttttcatcat aatctcttaa aatagtaaat aattatggca
    10741 gcccttgaaa atatattaaa aagtgtgttt tgagcggatg ttatgttgga ttg
//
LOCUS       DAJVBX010000167        10723 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.167, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000167 DAJVBX010000000
VERSION     DAJVBX010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 10723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10723
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.167"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(1..10196)
                     /gene="siiE"
                     /locus_tag="OPV72_003514"
                     /pseudo
     CDS             complement(1..10196)
                     /gene="siiE"
                     /locus_tag="OPV72_003514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463126.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="non-fimbrial adhesin SiiE"
     gene            complement(10213..>10723)
                     /gene="siiD"
                     /locus_tag="OPV72_003515"
     CDS             complement(10213..>10723)
                     /gene="siiD"
                     /locus_tag="OPV72_003515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="SPI-4 type I secretion system protein SiiD"
                     /protein_id="HCR9915717.1"
                     /translation="VIEKQINEEDIYSPVDGVIYKINKSATTHGGVIQAADLLFEIKP
                     KVRTMLADVKILPKYRDQIYVDEAVKLDVQSIIQPKIKSYNATIDNISPDSYEENTGG
                     TIQRYYKVIIAFDVNEDDLRWLKPGMTVDASVITGKHSIMEYLLSPLMKGVDKAFSEP
                     VNTKRLDTP"
BASE COUNT         2430 a         2896 c         2395 g         3002 t
ORIGIN      
        1 cgaagggtat atgtgccgtc aaccagagta ttcgggctgt caaaaatcca ctgtccgtcg
       61 gcatttttgc gtatcacatt ccagttagcg ccaccatcca gggttacgcg tacctggacg
      121 acatcaccgg gaacgtcaat tctgaatgac ggtttggcaa cattcgttaa ttgatcattc
      181 tgcacgccag tatcattaag caatacgata ttgttaatgg ttgtcgtggt atcaatacgt
      241 acctctaacg gcgcagattc ttttacattc cccgccagat cttccaccac aacggctaac
      301 tgatatgagc catcagccca gctcgcagaa ggcgtaaagc gccattaacc attggtgaat
      361 accgccgctt cctcgtgcgt tttaccgttg taagttactt tgaccatcac gcgcgtaacg
      421 tcagaatcaa tctggcgtat gtcgaacaca ggccgatcgt gattggtgag gcgatcgcca
      481 acagtaccgc tatcttcgcc ggccgccagc tcaatcaccg gcgtagtcaa cgtaccgtct
      541 atcgtcacct ttaaaggcgc ggatgtttgc tgattaccgg ccacatctgt taccgtcacg
      601 gtgaatgtgt agctaccgtc cgccaaagca gaatccggtc gatagcgcca gccgtcggct
      661 gattcggtga gtaccaccgt tttaaacgtg ccgttatgct caatactcaa ttccacgtgt
      721 cgaacatctt tatcgatact ccccaacaca aataccggct gagtgacgct ggtcagatta
      781 tcgttcttat tctgtccggt atcctgatcg ggcgctagct caatggttgg cgtcaacaac
      841 gtgatgtcga tagtgaaatc gagcgtcccc gtcatcttat tacccgcacc gtcagtcact
      901 tccacgatca gggtatgctg tccctctggc atatccgtcg gccaggtgta atcccaaatg
      961 ccaaccgtcg aactcttgat tgcagtaacc caggtcgtgc cgccgtcaat actcagaaga
     1021 accttttcca catcatccgg taccgagatc tggaactgcg gacgcacatg ttttgtcaca
     1081 ttatcgccag ggacgccgct atcgttgact aattcaatat gatcaatggc tatttgcgta
     1141 tccactgtca ccgtcagcgg cgtagacgga cgcgtatttc ccgcccgatc ctccactgtc
     1201 accgtcagcg tataatcacc gtcgccccac ggcgctggcg gtgtaaagct ccatcctcca
     1261 gccccctgtg tcgcggtaaa cgaggttgtc gttccattat gcgtgacgct gactgtaacg
     1321 ttgataacat ccgaatcgat attctgcaga ataaaagtcg gccgggtgcg attggtcata
     1381 tcatcgccag gcgtaccggt atcatccgtg ctatccagcg caatggtcgg cgtcgacaac
     1441 cgggtgtcga tgaaaaattc aagcgtttgc gtcgccgtat tgcccgctct gtcggtgacc
     1501 atgacggtta gggtgtgttt tccatcgccc atatccgttg gccaggtata gccccagacg
     1561 ccttcgatac cctgcgtcgc gctcacccag tttgcgcccc catcaatgct cagttgcaca
     1621 gaattcacat ccgccggcac cgtgatctca aactgcggac gggtgctatt agttagattg
     1681 tcatcaggca cgccatgatc attgaccaat gtaatatcag taatgctggt ttgcgtgtcc
     1741 accgtcacca ccagcggcgt ggactgacga acgtttcctg cgttatccgt tacctctacc
     1801 gtcagcgtat agctaccgtc cgcccagtca gcatctggcg taaagcgcca ctgtcctcca
     1861 acctgggtta gtgtcacttc ctggctattg ccgccctgtg tgatccgcaa aatgaccgag
     1921 tgcgcatcgg cgtcaatatt gccaatggta aagcccggtc ttttgacgct cgtaatatga
     1981 tcgccaatgg cacctgtatc gtccctgctg tccatagcga tggtaggcgt tgacagccgg
     2041 gtatcaatgg taaaatcgag cgtctgcgtc gtcttatttc ccgccttatc ggtcgcttct
     2101 accgtcaggg tatgtagccc gtcggtcaca tctttcggcc aggtgtaatc ccagatccct
     2161 gccgtgccct gtgttgcacg aacccacgta ttaccgccgt cgatactcag acgtacctcg
     2221 ttgacatccc ctggcaccgt gacgcggaag tgtggacgaa cgtcattggt caggttgtcg
     2281 ccgggaatac cgttatcatt aaccagttca ataacatcga tggtgatttg ggtatcaacc
     2341 gtgaccgtca gcggcgctga gtattttacg ttccccgcat catcctccac cctcaccgtc
     2401 agcgtatagt cgccatctgc ccatgtgccg gtcggtgtca cgctccagat gccggtcgcg
     2461 cctttggtgg ccgtcagcac ttctttcgtg ccgccatgct gcacctcaac cgtgacatac
     2521 cgcgcgtctg cgtcaatatt gcccagtaaa aacgtcggct tatttacgtt ggtcaggtta
     2581 tcgccttttg ttccgctgtc gtccgtgttg tccagcacga tagtcggttc tgacagtagg
     2641 gtatcgatga tgaagtccag ttgctgcgtc gttttgtttc ccgccttgtc ggtcgcctcc
     2701 actgtcaggg tatgcttccc ctctcccaca tcagccagcc aggtataatc ccagacaccc
     2761 ggcgtcgcgc tctgggtcgc gttgaaccac gtcttgccgc cgtcaatgct caggcgcacc
     2821 acgttgacat ccgtcggtac cgtcacctgg aagtgtggac gcacattatt agtcagatta
     2881 tcgttgggaa taccgctgtc attgaccagt tcaatgttat taatggcgat ttgcgtgtcc
     2941 accgtcaccg tcagcgatgc agaatggctg gtgttccccg ctttatcttc gactgacaca
     3001 ctcagggtat aatcaccatc cgcccacgcc cctgtcggcg taaaggtcca tccgcctgcg
     3061 tctttcgtgg cgtcaaatgt ggtggtgacg ccgccatgct ctacgctgac cgtaacgcga
     3121 acggcatcat catcaatatg ctgcagggca aatgtcggct gggtgcgatt ggtcatgtta
     3181 tcgccatgga caccactgtc gtccgcgcta tccagtacga taaccggcgt cgacaacgta
     3241 gtatcaatag tgaagtcgag cgtcctggtc accgtattgc ctgcgttatc agtcgctttc
     3301 accgttaacg tgtagtcacc atctgccact gtctttggcc aggtataatt ccagacgccc
     3361 ggcgtcgcgc tttgcatcgc tttaacccag gttacaccgc cgtcaatgct cagactgact
     3421 tcgttaacat cccccggtac cgtcacgcgg aactgcggat gggcgtcgtt agtcatattg
     3481 tcgccgggaa taccgttatc attaaccagt tcaataacat caatggtgat ttgggtatca
     3541 acagtgaccg tcagcgacgc tgagtgtttt tcgttccccg cctcatcttc caccctcact
     3601 gtcagcgtat agtcgccatc tgcccatgtg ccgatcggtg tcacgctcca gttgccggtc
     3661 gcgtctttgg tggccgtcag cacctctttc gtgccgccat gctgtacctc aactgtgaca
     3721 taccgcgcgt ctgcgtcaat attgcccagt aaaaacgtcg gcttatttac gttggtcagg
     3781 ttatcgcctt ttgttccgct gtcgtccgtg ctgtccagca cgatagtcgg ttctgacagt
     3841 agggtatcga tgatgaagtc cagttgctgc gtcgttttgt ttcccgcctt gtcggtcgcc
     3901 tccactgtca gggtatgctt accctctccc acatcagcca gccaggtata atcccagacg
     3961 cccggcgtcg cgctctgggt cgcgttgaac cacgtcttgc cgccgtcaat gctcaggcgc
     4021 accacgttga catccgtcgg taccgtcacc tggaagtgcg gacgcacatt attagtcaga
     4081 ttatcgtcgg gaataccgct gtcattgacc agttcaatat ggtcaatggt gatttgcgta
     4141 tcgatggtga ccgtcaacgg cgctgagtgg cgaatattac ccgcctcatc tttcaccgtt
     4201 accgtcagcg tatagtcgcc atcagtccac gcgctgccgg gtacaaaacg ccactgcccg
     4261 ttagtctgcg tcagctccac ctcctcgctg tgaccatcgc gcatcacctg cacgacgacc
     4321 tgagtcacgt cagaatcaat accgccgata ataaaacccg gcgttttaac gttagtctta
     4381 ttatcgttgg cggtgccgct atcatctgcg ctatccagcg tgatggtcgg tgtcgacaat
     4441 gtggtatcaa tgataaaatt gagcgtttcc gtcgccgtgt tgcctgcaac atcggttgct
     4501 ttcactgtca gggtatacgt attttcgacc agatctgtcg gccatatata ctcccaaacg
     4561 ccgtcagacg tcagcgttgc gttaacccag ttgatgccgc catcaagact cagttgcaca
     4621 gagttcacgt ccgtcggtac cgtaatatga aactgtggac gtgcttcatt ggtcaggtta
     4681 tccccgacaa tacccgtgtc attaagaagc ccaatgcgat caatagacgt ttgcgtatcg
     4741 atagtcaccg tcagcggcgc agaataattt gtattacccg ccttatcttc tacctttacc
     4801 gtcagcgtat agtcgccatc ggtccaggct gcgcccggcg taaagcgcca cacaccgccg
     4861 ttcttaatca actctatctg ttggttctta ccatcatgcg ccaccgtcac caccactttg
     4921 gtcacgtcgg cgtcgatatt accgagggta aagcctggca tcttaacgtt ggtgatgtta
     4981 tcgccagcgg cgctgtcatc cgcactgtcc agggtaatag tcggttctga cagcagggta
     5041 tcgatgatga agtccagttt ctgcgtcgtt ttgtttcccg ccttgtcggt cgcttccacc
     5101 atcagggtgt gagggccgtt agccacattc gtcagccagg tataatccca gacgcccgac
     5161 gtcgcgctct gcgtggcgtc aaaccacgtt ttgccgccat caatgctcag tcttacaccg
     5221 ttaacatccg ccggtactgt cacctgaaag tgcgggcgcg cttcattggt cagattatcg
     5281 tcggggatac tgctgtcgtt aaccagttca atacggtcaa tggcgatatg cgtgtccact
     5341 gtcaccgtca acggcgcgga ctgcttcaca tttccggccc tgtcttctac cttcaccgtc
     5401 aggatatagc cgccgtccgc ccagtcgctg gtcggcgcaa agcgccactg tccgccggtc
     5461 tgaaccagtg gtacctcctg tttaatgcca ttgtgcatta cctccactat cacccggctg
     5521 acatcggtat caatattgtt gagggtaaag cccggcgttt taacactggt gatattatcg
     5581 cccgcgatgc cgctgtcatc tgcgctgtcc agcgagaggg tcggcacaga cagagtggta
     5641 tcgatggtga aatcgagcgt ctgtgttgcc ttatttcccg cctcatcggt cgcttctacc
     5701 gtcagggtat agcctccgtc ggccacatca tccggccaga tataatccca gacgcccggc
     5761 gtcgcgctct gggtcgcgtt gaaccacgtc ttgccgccgt caatgctcag gcgcaccacg
     5821 ttgacatccg tcggtaccgt cacctggaag tgtggacgca cattattagt cagattatcg
     5881 ttgggaatac cgctgtcatt gaccagttca atgttattaa tggcgatttg cgtgtccacc
     5941 gtcaccgtca gcgatgcaga atggctggtg ttccccgctt tatcttcgac tgacacactc
     6001 agggtataat caccatccgc ccatgatgtc ggcggcgtaa aggtccatcc gcctgtgcct
     6061 ttcgtggcgt caaatgtggt ggtgacgccg ccatgctcca cgctgaccgt aacgcgaacg
     6121 gcatcatcat caatatgctg cagggcaaat gtcggctggg tgcgattcgt catgttatcg
     6181 ccctggacac cggtatcgtc cgcgctattc agtacgatga ccggcactga cagcgtggta
     6241 tccaccgcga aatcgatggt cttcgtcact gtattgcctg ctttatcagt cgcttccacc
     6301 gttagcgtgt attgaccatc tgccaggtct gtcggccaga tatactccca gcttcctgcc
     6361 acgcccgggg ttgcctgaac ccacgaatta ccaccgtcaa tgctcagacg gacttcattg
     6421 acatccgtag gtaccgtcac acgaaagtgg ggacggtcgt cgttggtcat attgtcgcct
     6481 ttcacgccgc tatcgttgac cagttccacc ccatcaatgg cgatttgggt atcgataacg
     6541 accgtcagcg gcgctgaata gctggtattt cctgccttat cttctacttt caccgttaac
     6601 gtgtagctgc catccgccca cgtattccct ggtgtaaata accaactacc attgaggtgg
     6661 gaaagttcga tctcttcgct cacgccattg tgcatcacct gtacgacgac ccgatgcgca
     6721 tcggcatcaa caccggaaat agcaaaacct ggcttattga tattggtcag gttatcgcct
     6781 gtcacccccg tatcatcctt agaaagcagg gaaatcaccg gcgttgatac tgtggtatcg
     6841 atagtaaaat cgaataccgc gctgttcgct ttattacccg caatgtcctc aaccttgaca
     6901 taaacctgat gcaagccttc cgttaaatct gaagtaaagg tataggtcca tgaaccatca
     6961 ggttgttgcg tggcaacacc gatctgcgta tcagacgcgg catcccatac ctgaacgctg
     7021 ataatgtccg gatcaatatc ttttaggtgc aaggtagggt taacgatatt cgttaaatta
     7081 tcatctgcga ttcccgaatc tgaatccggg ctcaatgaaa ctatcggtat tgaaatagca
     7141 gtatcaacgc taattaagaa aggatccgaa tgcgcaatgt tgccagcgat atcttcaact
     7201 gaagcggtta ttctatgatc gccatcaacc aaaccttgat cggctttcag ggtatactcc
     7261 catctgctat ctttatttgt tctgacctca gcgattagtg cgccatcaac atagagttta
     7321 accgttgaat agggtgcagc ggtccctgtc agtgcaggat tcttttcatt aataatatgg
     7381 tctgtattat caacccccgt atcgttgacc aactctattg ttggtttttg cgtttgcgtt
     7441 acgatttgga aattatacgc tgatgaggag gcagtattac cggcaatatc ttctaccttt
     7501 accgttacgt catgcgagcc atcggacaac gctgtggtaa attgaaaatt ccatacacca
     7561 tcatcgccag caatagcctc gccacttaac acaccgtcaa catagatgga aaccttagca
     7621 ttagcttcag ccatcccggt aaacaacggc gtattaattt tagtaatcat atcgccttta
     7681 acgccagagc cagcgctatc atgcaacata acagtaggga tcggcgtaaa gctatcaatg
     7741 gtaagctgat aatctacaga tgacgttctt cctaaaggat cgatagattc aaccgtaatc
     7801 ttataaacat tgtcagacag atttcgggaa atatcaaaat tccagttacc gtctgcatcc
     7861 gcagtcgtca cgcctatcgt tttaccatcg ataaggatat ttatggtagc aaacctatcc
     7921 gctgttccca gtaatgtcag agcattatgt ttattggtaa tccagtcgcc ttttgcaccg
     7981 gaatcatcac tggcatcgag ttccgctttt ggaggtacaa cttcagtttg aatagtaaaa
     8041 gaatatttaa cagtagagga tttattaccg gcggcatcct gagaaatgat ttcaatatca
     8101 taggcgccct gaagaaattt attactaaac tgataattcc aggtcccgtt tgagtcaacc
     8161 tcaatgctgt catataattt accatctcgc atcaataaga tggtagactt tggctctgcc
     8221 gtaccgacta aagccggtaa atcattccct gataaaatta taccattcgg taaaacaaca
     8281 aaatcctcca aagaaaccgt cggaggtaca ggggcaacag tatcgataac gtaactaaag
     8341 gaaaaatcct ttttgttgcc agcgacatct tcaacagtga acgtaagatt gttaacccct
     8401 tccactgagt ctgaagtgaa attgaacgtc cattcgccct tgtcattcgc tttaaaaata
     8461 acctcttcgc cagtctcact atttatgaca ctgataatag catttggctc agttttacct
     8521 gtaaaggttg ggcgagtatt gttagtaacg ttatctccaa caataccgct atcatcagtc
     8581 gtttcaatct cagcgctgaa atagctgata cgggtatcaa tagtaaaagg cagatttgcc
     8641 gtcgcagagg tatgcccggc aatatcagta gcggttgctg ttatattgta ttcgccatcc
     8701 ttgagcggcg tagtaagcgt atagctccat gtcccatctt tagcaacaat gacctcacca
     8761 agatgtttaa gcccaagata aatagagact gtagaaccag gttccgccac accaataaat
     8821 gttggcagag tgctatttgt aatgttgtca tttttaatgc cggaatcact actatcatcc
     8881 agctcaatcg tcggcttttc cggaggaatg gtgtcggtta tgatactatc cgtcgtttcg
     8941 tttttattac ctgctttatc cacggcaacg acttttatac tattttcgcc ctcagataat
     9001 tcattatctt taaattcata actccagttt ccatctttat cgacatcaac gctggcaacc
     9061 agtttattat ctacataaat gtcaacctta gcattctctt ccgccgtacc aacaattgaa
     9121 ggcgtcaagg tcggcgttaa gcccttatga ccggacacac tactttcagg cgaaagttca
     9181 aatgttggct tatcggtaac ggaatcgata gtaatgacaa gtttggcgct accgcttcca
     9241 tcagcagtct tggcctctgc ctccagattg tatgttccat cagtcaatgt ttcaggcgct
     9301 gtgaaggtga agttacccaa actatccgct acagcctgac cgacagcaat accattaatt
     9361 ttaataataa ccgtggcatt gggagcagtg ctacctacaa actgaggttt ggtaaaatta
     9421 gttatactat catctttgct accgctgtta ctctcggccg caagcgctaa tgtgacttta
     9481 agcggctctt taacagactc ggcatcgagc ttattttcct catttttact gctattactt
     9541 ttgccagtac tggtattttt attaataggt tgaggaagaa ctttttcagc atcgttctgt
     9601 ttagaagcct gcgttgcttt agcctgtgta ttttgctggg aagcatcgct ttgctgagcc
     9661 agattgtctt ttgctacatt gtcagccaaa aagttctgca gcatttcttc aatttgcttt
     9721 gacgagttct gtacttcaaa cgcttcattg agcgtttttt ctgctgcctc cttagctttc
     9781 tctgcttctt ccttcgcctt atcagcttct ttctttgcgt tttcagcctc gtcaagctgc
     9841 ttttttaatt cctcttcttc cttcttattt cgtcgtttgc cattaccttt cttttctacc
     9901 tgagcagaat caactaatga gctgtcaatt ctctccagtt gaatatcttt taaatctacg
     9961 ctgcccagaa ttttagcgcc ggtaatagtc ttatctttaa atttaacagc gaggttattg
    10021 cctttgatac ttgaataaag agcgccattg acaatgatca ctgacccatg cggcgtggta
    10081 atgttcatgt ctggcccgga aagagaaact tttgcgcctt tggcattacc caaagaagat
    10141 aaatcaatta cagaattttg atcggcaaaa aacttttgta tgcttttatt tcccataata
    10201 ttatattcac tctcaaggtg tatctaatcg tttagtatta actggttctg aaaaggcttt
    10261 gtccacgcct ttcatcaaag gagataacag gtattccata atgctgtgtt ttccggtaat
    10321 tacactggcg tcaacagtca tacctggttt taaccaccgt aaatcatctt cattaacatc
    10381 gaatgcaata attactttat aataacgctg aattgttcct ccggtatttt cctcataaga
    10441 gtcagggcta atattatcga tagtcgcatt atacgatttt atctttggtt gaataattga
    10501 ctggacatct agcttaacgg cttcatctac atatatttgg tcacggtatt ttggtagtat
    10561 tttcacatcg gccagcatag tccttacttt tggttttatt tcaaaaagta agtccgccgc
    10621 ctgaatcaca ccaccatgag tagtggcact tttattgatt ttataaatta caccgtcaac
    10681 cggtgaatag atatcctcct catttatctg cttctctatt act
//
LOCUS       DAJVBX010000168        10601 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.168, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000168 DAJVBX010000000
VERSION     DAJVBX010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 10601)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10601)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10601
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.168"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            101..184
                     /gene="yohP"
                     /locus_tag="OPV72_003516"
     CDS             101..184
                     /gene="yohP"
                     /locus_tag="OPV72_003516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YohP"
                     /protein_id="HCR9915718.1"
                     /translation="MKILLWAILIIFLIGLLVVTGVFKMIF"
     gene            complement(242..1180)
                     /gene="dusC"
                     /locus_tag="OPV72_003517"
     CDS             complement(242..1180)
                     /gene="dusC"
                     /locus_tag="OPV72_003517"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine(16) synthase DusC"
                     /protein_id="HCR9915719.1"
                     /translation="MRVLLAPMEGVLDALVRELLTEVNDYDLCITEFVRVVDQLLPVK
                     VFHRICPELLHASRTPSGTPVRIQLLGQHPQWLAENAARATALGSYGVDLNCGCPSKV
                     VNGSGGGATLLTDPELIYQGAKAMRAAVPSHLPVTVKVRLGWDSGDRKFEIADAVQQA
                     GASELVVHGRTKAQGYRAEHIDWQAIGEIRQRLTIPVIANGEIWDWQSAQACMATSGC
                     DAVMIGRGALNIPNLSRVVKYNEPRMPWPEVVTLLQKYTRLEKQGDTGLYHVARIKQW
                     LGYLRKEYIEATELFQSIRALNRSSEIARVIQAIKI"
     gene            complement(1289..2482)
                     /locus_tag="OPV72_003518"
     CDS             complement(1289..2482)
                     /locus_tag="OPV72_003518"
                     /EC_number="1.14.13.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybenzoate 6-monooxygenase"
                     /protein_id="HCR9915720.1"
                     /translation="MTHVTSAIIVGGGIGGAATALSLARQGIKVMLLEKAHEIGEIGA
                     GIQLGPNAFSALDSLGVGDVARQRAVFTDHITMMDAVNAEEVVRIETGQAFRDHFGGP
                     YAVIHRVDIHATVWEAVLTHPGVEYRTSTHIVDIRQTPDDVTVFDEQGNSWTADILVG
                     CDGVKSVVRQSLLGDAPRVTGHVVYRAVIDCDDMPDDLRINAPVLWAGPHCHLVHYPL
                     RGGQQYNLVVTFHSRQQEEWGVKDGSKEEVLSYFAGIHPRPRQMLDKPTSWRRWSTAD
                     REPVAKWGTERITLVGDAAHPVAQYMAQGACMALEDAVTLGKALERCDGDAQQAFALY
                     ESVRIPRTARIVWSTREMGRLYHAAGVERQVRNLLWKGKSQEAFYRGIEWLYGWKEDN
                     CLEPR"
     gene            complement(2497..3141)
                     /gene="maiA"
                     /locus_tag="OPV72_003519"
     CDS             complement(2497..3141)
                     /gene="maiA"
                     /locus_tag="OPV72_003519"
                     /EC_number="5.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maleylacetoacetate isomerase"
                     /protein_id="HCR9915721.1"
                     /translation="MKLYSFFNSSASYRVRIALALKGIDYQTVGVNIRIGQQNALAYR
                     RMNPVGLVPTLVTDDGESLGQSLAIVDWLDRHFPQTPLLPTSDPARSQALEIVYAIAC
                     DIHPINNMRVLRYLTDELKVSEEDKKRWYAHWIQQGLSAVEQLLRKSQSGRFCVGDAP
                     GLADCCLIPQWANALRMGCDLSGYPRCKAVYDACVQLPAFIAAAPENQQDKIPA"
     gene            complement(3150..3851)
                     /locus_tag="OPV72_003520"
     CDS             complement(3150..3851)
                     /locus_tag="OPV72_003520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HCR9915722.1"
                     /translation="MTKYVFQPQAPVTVPVAGSDEQFPVRRVYCVGRNYAAHAREMGF
                     DPDREPPFFFCKPADAVVPVAAGDTLELPYPAQTDNYHYEIELVVAIGKKGSDIPLEK
                     AHEYVWGYATGLDMTRRDRQMEMRQMGRPWEIGKAFDLSAPIAPLHKAAETHNVDNAP
                     IWLQVNGEDHQRSDIRHLIWSVNETISYLSGFFELQPGDLIFTGTPEGVGAVVKGDVI
                     TGNVEGLTPIAVKIV"
     gene            complement(3867..4904)
                     /gene="gtdA"
                     /locus_tag="OPV72_003521"
     CDS             complement(3867..4904)
                     /gene="gtdA"
                     /locus_tag="OPV72_003521"
                     /EC_number="1.13.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gentisate 1,2-dioxygenase"
                     /protein_id="HCR9915723.1"
                     /translation="MSEINQNVKDSRQQYYQHISGQNLTPLWESLHHLVPQTPNANCA
                     PAYWNYQEIRPLLMESGNVIGAKEAIRRVLVLENPALRGQSSITATLYAGLQLILPGE
                     VAPSHRHNQSALRFIVEGKGAFTAVDGERTPMHTGDFILTPQWRWHDHGNPGSEPVVW
                     LDGLDLPLVNLLGCGFAEDYPEDQQPVTRKEGDYLPRYAANMLPLRHQRGNSSPIFNY
                     RYDRSREALHDLTRMGDPDEWEGYKLRYVNPVTGGYPMPSMGAFLQLLPKGFASRVAR
                     STDSTIYHVVEGAGQVTIGNETFHFSAKDIFVAPTWHEVSFRSSEDTVLFSFSDKPVQ
                     EALGLFREARY"
     gene            complement(4916..6274)
                     /locus_tag="OPV72_003522"
     CDS             complement(4916..6274)
                     /locus_tag="OPV72_003522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid/H+ symport family MFS transporter"
                     /protein_id="HCR9915724.1"
                     /translation="MTQRRDLQALIDAAPVGKMQWRVIICCFLVVMLDGFDTAAIGFI
                     APDIRTHWQLSASELAPLFGAGLLGLTAGALLCGPLADRFGRKRVIELCVALFGALSL
                     LSAFSPDIETLVLLRFLTGLGLGGAMPNTITMTSEYLPARRRGALVTLMFCGFTLGSA
                     MGGIVSAQLVPLIGWHGILALGGILPLMLFFGLLFALPESPRWQVRRQLPQAVVARTV
                     SAITGERYHDTQFFLHETAAVAKGSIRQLFAGRQLVITLMLWVVFFMSLLIIYLLSSW
                     MPTLLNHRGIDLQQASWVTAAFQVGGTLGALLLGVLMDRLNPFRVLAVSYALGAVCIV
                     MIGLSENGLWLMALAIFGTGIGISGSQVGLNALTATLYPTQSRATGVSWSNAIGRCGA
                     IVGSLSGGMMMALNFSFDTLFFVIAIPAAISAVMLTLLTVVVRLSISVPDDLPRASVV
                     NE"
     gene            6400..7308
                     /locus_tag="OPV72_003523"
     CDS             6400..7308
                     /locus_tag="OPV72_003523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCR9915725.1"
                     /translation="MANWAQKLKLHHLQTLVALGEQGNLTHVARMMNISQPALSKWLS
                     QLEDEIGITLFERHSKGLRPSEGGKLLLQHAQRLINDLERSQYEIARFKQGGLVGSLK
                     IGCSPVATDCVSQAILSLLNEMPTPHLNIEEKVMTPLLHDLLAGQVDVVVGRVGGRAL
                     QLPLNYQVLYTEPVCFVARPHHPLAARAQIAWSDLAHWRWIVWPTGTPIRISIDNALV
                     DNGVMLPENTIESASMNVSTNLLQSSDMISILSLRLAQRYASQGQLAILNLPKIEQKG
                     SVGMFWRKNETPSLALSRFLYFLAQV"
     gene            7440..7838
                     /locus_tag="OPV72_003524"
     CDS             7440..7838
                     /locus_tag="OPV72_003524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HCR9915726.1"
                     /translation="MSKSLNIIWQYIRAFVLIYACLYAGIFLASLLPITIPGSIIGML
                     ILFVLLALQILPAKWVNPGCYVLIRYMALLFVPIGVGVMQYFDLLRAQFGPVVVSCAI
                     STLVVFVVVSWSSHLIHGERKVVGQKGTKK"
     gene            7835..8530
                     /locus_tag="OPV72_003525"
     CDS             7835..8530
                     /locus_tag="OPV72_003525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidB/LrgB family autolysis modulator"
                     /protein_id="HCR9915727.1"
                     /translation="MMTYIWWSLPLTLAVFFAARRLAAHFKMPLLNPLLVAMVVIIPF
                     LLLTGIPYEHYFKGSEVLNDLLQPAVVALAYPLYEQLHQIRARWKSIISICFVGSLVA
                     MITGTSVALLMGATPEIAASVLPKSVTTPIAMAVGGSIGGIPAISAVCVIFVGILGAV
                     FGHTLLNAMHIRTKAARGLAMGTASHALGTARCAELDYQEGAFSSLALVICGIITSLV
                     APFLFPLILAVMR"
     gene            8684..9568
                     /gene="cdd"
                     /locus_tag="OPV72_003526"
     CDS             8684..9568
                     /gene="cdd"
                     /locus_tag="OPV72_003526"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HCR9915728.1"
                     /translation="MHPRFQTAFAQLADNLQSALAPILADHHFPAMLTAEQVSTLKNT
                     AGLDEDALAFALLPLAAACARTDLSHFNVGAIARGVSGNWYFGANMEFLGATMQQTVH
                     AEQSAISHAWLRGEKGLAAVTVNYTPCGHCRQFMNELNSGLDLRIHLPGRAPHTLRDY
                     LPDAFGPKDLEIKTLLMDEQDHGFTLTGNTLTQAAITAANKSHMPYSHSPSGVALECK
                     DGRIFTGSYAENAAFNPTLPPLQGALNLLSLNGYDYADIQRAILAEKGDAALIQWDAT
                     AATLKALGCHNIDRVLLG"
     gene            9745..10464
                     /gene="sanA"
                     /locus_tag="OPV72_003527"
     CDS             9745..10464
                     /gene="sanA"
                     /locus_tag="OPV72_003527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane permeability protein SanA"
                     /protein_id="HCR9915729.1"
                     /translation="MLKRVFYSLLVLVGLLLLTVLGLDRWMSWKTAPYIYDELQDLPY
                     RQVGVVLGTAKYYRKGVINQYYRYRIQGALNAYNSGKVNYLLLSGDNALQSYNEPMTM
                     RKDLIAAGVDPADIVLDYAGFRTLDSIVRTRKVFDINDFIIITQRFHCERALFIALHM
                     GIQAQCYAVPSPKNMLTVRLREFGARFSALADLYIFKREPRFLGPLVPIPTQHQVPND
                     AQGYPAVTPEQLLELEKKKGK"
     gene            10461..>10601
                     /locus_tag="OPV72_003528"
     CDS             10461..>10601
                     /locus_tag="OPV72_003528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2542 family protein"
                     /protein_id="HCR9915730.1"
                     /translation="MIMDVQTIFVILAFLLLPLFCFREAWKGWRTGAVDKVVKNARKP
                     VYV"
BASE COUNT         2365 a         3051 c         2794 g         2391 t
ORIGIN      
        1 agcagccttc atgagttaaa cgtcgccgcg cccaacaaag cagcagatgg cttaatactt
       61 tcctatactt tgtttgtatt taccaataaa gggacaaaca atgaaaattc ttctatgggc
      121 aatcttaatt atttttctga ttgggctgtt ggtggtaacg ggcgtgttta agatgatttt
      181 ctgattcctg cgccgggcag cgatagtatc tgcccggcac acgttctgga cgctgtagag
      241 attagatttt aatagcctga atcacccgcg caatctcgga cgaacggttt aacgcccgaa
      301 tcgactgaaa gagttctgtc gcctcaatat attccttacg taaatatccc aaccactgtt
      361 taatacgcgc gacatggtat aaaccggtat cgccctgctt ttccagtcgg gtatattttt
      421 gtaataacgt taccacttcc ggccacggca tacgcggttc gttatacttc accacccggc
      481 tcaggttagg aatatttaac gccccgcggc caatcatcac cgcatcgcag ccgctggtcg
      541 ccatacatgc ctgcgcgctc tgccagtccc agatttcgcc attagcgata accggaatag
      601 tcagacgctg gcgtatttcg ccgatcgcct gccagtcgat atgctcggcg cggtagccct
      661 gcgctttggt acggccatgc accaccagtt cactggcgcc ggcctgctgc accgcatcgg
      721 cgatttcaaa ttttctatcg ccgctatccc agccgagacg cacttttacc gtcaccggca
      781 gatgcgacgg taccgcggcc cgcatcgctt tcgcgccctg atagatgagt tcgggatctg
      841 tgagcaatgt cgcgccgccg ccgctgccgt tcaccacttt tgacggacag ccgcagttca
      901 ggtccacgcc atacgatccc aacgccgtcg cccgcgcggc gttttccgcc agccactgcg
      961 gatgctggcc cagaagctga atacgcaccg gcgtgccgga cggcgtgcgg ctggcgtgaa
     1021 gcaactccgg gcagatgcga tgaaacactt ttaccggcag cagctgatcc accacgcgca
     1081 caaattcggt gatgcagaga tcgtaatcat tcacttcggt cagcagctcg cgcactaacg
     1141 cgtcgagcac gccttccatc ggcgccagta aaacacgcat atcggtatcc acagcaaaaa
     1201 aagaggcgct atcataacgc ctctctgcga tgagcaaaac tttttgccgg gtggcggcgc
     1261 aaacgccacg ctacgtcacg taaggcgctc aacgcggctc aagacagtta tcttctttcc
     1321 agccgtacag ccattcgata ccgcgataaa acgcctcctg cgatttccct ttccacagca
     1381 gattacgcac ctgacgctcc accccggcgg cgtgatagag acgccccatc tcgcgggtag
     1441 accagacgat acgcgccgtg cggggaatac gcaccgactc atacagcgca aatgcctgct
     1501 gcgcgtcgcc gtcgcagcgt tccagcgctt tgcctagcgt gacggcgtct tccagcgcca
     1561 tacaggcgcc ctgggccata tattgcgcca ccggatgcgc ggcgtcgccc accagagtga
     1621 tacgctcggt tccccatttt gcgaccggct cgcgatcggc ggtcgaccag cggcgccagg
     1681 aggtcggctt atccagcatc tgacgcgggc ggggatgaat accggcaaaa taagagagca
     1741 cctcttcttt actgccgtct ttcacgcccc actcttcttg ctggcggctg tggaatgtca
     1801 ccaccagatt gtactgttgg cctccgcgca gcggataatg gaccaggtga caatgcgggc
     1861 ctgcccacag caccggtgcg ttaatacgta aatcgtccgg catatcgtcg caatcaatca
     1921 ccgcccgata gactacatgc cccgttacgc gcggcgcgtc gccgagtaaa ctttgccgca
     1981 cgaccgattt aacgccgtcg cagcccacga gaatatccgc cgtccagcta tttccctgct
     2041 catcaaacac cgtaacgtca tccggcgtct ggcggatatc gacaatatgg gtcgaggtac
     2101 gatactccac gccagggtgc gtcagcaccg cttcccatac cgttgcatga atatctaccc
     2161 ggtgaattac cgcatacggc ccgccaaaat ggtcgcggaa cgcctgcccg gtttcaatgc
     2221 gtaccacttc ttcggcattc acggcatcca tcatggtaat gtgatcggta aacaccgcac
     2281 gctggcgggc aacatcgccc acaccgagac tatccagcgc cgaaaaagcg ttcggcccaa
     2341 gctgaatacc cgcgccaatc tcgccaattt cgtgcgcttt ttccagcagc atgactttta
     2401 ttccctggcg cgccagcgac agcgcggtcg ccgcgccgcc gattccgcca cctacaataa
     2461 ttgcgcttgt cacgtgagtc atggtcattc tccttttcag gccgggattt tatcttgttg
     2521 attttccggc gcggcggcaa taaacgccgg tagctgtacg caggcgtcat aaacggcttt
     2581 acagcgcgga tagcctgata aatcgcagcc catcctgagc gcattcgccc actgaggaat
     2641 caggcagcag tccgcaaggc ctggcgcgtc gcccacgcag aatcgtccgg actgactttt
     2701 acgcaatagc tgctctaccg cgcttaaccc ttgctgtatc cagtgggcgt accagcgttt
     2761 tttatcctct tcgctaacct tcagctcatc ggtcaggtag cgcaacacgc gcatgttatt
     2821 gatcgggtgt atatcgcagg cgatagcgta gacaatttcc agcgcctggc tgcgcgccgg
     2881 gtcgctcgtc ggcagcagcg gcgtttgcgg aaaatgtcgg tccagccagt cgacgatggc
     2941 cagcgattgc cccaacgatt cgccgtcatc agtgactagc gtcggcacca ggcctaccgg
     3001 attcatccgt cggtaggcca gcgcattctg ctggccgata cgaatattga cgcccactgt
     3061 ctggtaatca atccccttta acgccagcgc aatacgtaca cgataagacg ccgaactatt
     3121 aaagaaactg tacagcttca tcgttcacct cagacaattt tcacagcaat cggcgtcaga
     3181 ccttctacgt tcccggtgat gacatcccct ttcaccactg cgcccacccc ctctggcgta
     3241 ccggtgaaaa tcaaatcgcc tggctgcaat tcaaaaaagc cggacaaata gctgatggtt
     3301 tcattcaccg accaaatcag atgacgaata tcgctgcgct gatggtcttc gccgttaacc
     3361 tgtagccaaa taggggcgtt atccacatta tgcgtttcag cggctttgtg taatggcgca
     3421 atgggcgcgg agagatcgaa cgctttgcca atttcccacg ggcgtcccat ctgacgcatt
     3481 tccatctgac gatcgcgacg cgtcatgtcc agaccggtgg cgtatcccca gacatattca
     3541 tgggcttttt ctagcgggat atcgctcccc tttttaccaa tcgccaccac cagctcaatt
     3601 tcataatggt agttatcggt ctgcgccgga tacggcagtt ccagggtatc ccccgccgct
     3661 accgggacga cagcgtccgc tggtttacaa aagaagaacg gcggttcgcg atcgggatca
     3721 aaacccattt cacgggcatg ggcggcatag ttgcgaccca cgcagtaaac gcgacgtacc
     3781 ggaaactgct catcactgcc cgccacgggt actgtcaccg gggcctgcgg ctggaataca
     3841 tatttggtca tgttctctct ccctaattaa taacgtgctt cgcggaacag ccccagggct
     3901 tcctgaaccg gcttgtccga aaagctgaat aacaccgtgt cttcgctgct gcgaaacgac
     3961 acctcatgcc aggtcggcgc cacaaaaatg tcttttgcgg aaaaatgaaa agtttcgttg
     4021 ccgatagtga cctgccctgc cccttcaacg acgtggtaga tagtgctgtc ggtgctccgc
     4081 gccacacgcg aggcaaagcc ttttggcagc agttgcagga acgcgcccat cgacggcatc
     4141 ggataaccgc cagtgacggg attaacgtaa cgcagcttgt agccttccca ctcatccgga
     4201 tcgcccatac gggtcagatc gtgcaacgcc tcgcgactgc ggtcgtaacg gtagttgaaa
     4261 atcggcgacg agttcccgcg ctggtggcgc agcggcagca tattcgctgc atagcgcggc
     4321 agataatcgc cctcttttcg cgtcaccggc tgctgatctt cgggatagtc ttccgcaaaa
     4381 ccacagccca ggagattgac taacggcaga tccagaccat ccagccatac caccggctct
     4441 gatcccggat taccatgatc gtgccagcgc cactgcggcg tcaggataaa atcgccggta
     4501 tgcattggcg tgcgctcgcc gtccaccgcg gtaaatgcgc ctttaccttc gacgataaaa
     4561 cgcagcgccg actggttatg gcgatgactc ggcgcgactt cgccgggcag gatcagctgt
     4621 aaaccagcgt ataaggtcgc cgtgatcgac gactgaccgc gcaatgccgg attttccagc
     4681 accagcaccc ggcggatcgc ctctttcgcg ccaatgacat tgccgctttc catcagtagc
     4741 ggacgaattt cctgataatt ccagtaggcc ggcgcgcagt tggcgtttgg cgtctgcggt
     4801 accaggtgat gtaacgattc ccacagcggc gtcagattct gcccggaaat atgctggtaa
     4861 tactgctgac ggctatcttt tacgttctga tttatttcag acatggagat tctccttatt
     4921 cgtttacgac gctggcacgc ggcaggtcgt caggtacaga aatcgaaagg cggacaacca
     4981 ctgtcagcag ggtaagcatt accgcgctga tagccgccgg aatagcaatg acaaaaaaca
     5041 acgtatcgaa agagaaattg agggccatca tcatgccgcc ggagagcgaa ccgacaatcg
     5101 ccccgcagcg tccaatggcg ttcgaccagc tcacgcccgt cgcccggctt tgggtggggt
     5161 acagcgtcgc cgtcagagca ttcagcccga cctgggaacc gctaataccg atgccggtac
     5221 caaaaatcgc cagcgccatc agccaaaggc cgttttcgct caggcctatc atgacaatgc
     5281 aaactgcgcc cagcgcatag ctcaccgcca gtacccggaa cgggttaagc cggtccatca
     5341 acacgccgag taacagcgcg ccaagcgtgc cgcccacctg gaatgcggca gtcacccacg
     5401 acgcctgttg cagatcaata cctcgatggt taagtaacgt cggcatccag ctggaaagca
     5461 gatagataat gagcaggctc ataaagaaca ccacccataa catcagggta atgacaagct
     5521 gtcgcccggc aaaaagctgg cgaatactgc ctttggcgac ggctgccgtc tcatgcagaa
     5581 agaattgcgt atcgtgatag cgctcgccgg taatggcgct gaccgtccgg gcgacaacgg
     5641 cttgcggtag ttggcgacgt acctgccagc ggggagattc cggcagcgcg aacagcaggc
     5701 cgaaaaacag catcaaaggc aagatgccgc ctagcgccag aattccgtgc cagccaatca
     5761 gcggcaccag ttgcgcgctc acaatcccgc ccatcgccga ccccagggta aaaccgcaga
     5821 acatcagcgt gaccagcgct ccgcgtcgac gagcgggaag gtattccgac gtcatggtga
     5881 tggtattcgg catcgctccg cccagtccca gaccggttaa gaagcgcagc aacaccaggg
     5941 tttctatatc cggcgagaaa gcggaaagca ggctcaatgc gccgaatagc gccacgcaaa
     6001 gctcaatgac ccgcttgcgg ccaaagcgat ccgccagcgg cccgcatagc agcgcgccgg
     6061 ccgtaagccc cagcagccct gcgccaaaca gcggcgcaag ttcgctggcg cttagctgcc
     6121 agtgagtacg aatatccggg gcgatgaagc caatcgcggc ggtgtcgaaa ccgtcgagca
     6181 taaccaccag aaaacagcag atgataacgc gccactgcat tttgccgacg ggcgcggcat
     6241 caataagggc ttgtagatca cgtcgttgag tcatagctaa tgcctcagtg cagggagata
     6301 gatgttgttt ttatgtttgc tatgttacga gtttgtagag tgagcgataa aatgtacaat
     6361 ggcttttcag gcagagacat aacctggagg ttatagcgaa tggcgaactg ggcgcagaaa
     6421 ttgaaattac atcacctgca aacgctggtt gcgctgggcg aacagggcaa cctgacgcac
     6481 gtcgcccgga tgatgaatat ctcccagccg gcgctatcga agtggctatc tcaactcgaa
     6541 gatgagatag gcatcacgct ttttgagcgc cacagtaaag gactacgccc ctcggaaggc
     6601 ggtaaattac tgctccagca cgcccagcgc ctaattaacg atctggagcg ttcacagtat
     6661 gaaatcgccc gtttcaagca gggcggcctg gttggcagcc tgaagatcgg ctgttcgccc
     6721 gtggcgactg actgcgtatc acaggcgatt ctgagcctgc ttaacgaaat gccgacgccg
     6781 catctgaata ttgaagagaa ggtaatgacg ccgctgctgc acgatttgct tgccggtcag
     6841 gtggatgtgg tggtagggcg tgtcggcggc cgcgccctgc aactgccgct taattatcag
     6901 gtactttata ccgagccggt ctgctttgtg gcgcgtccgc accatccgct ggccgcgcga
     6961 gcgcagatcg cctggagcga tctggcacac tggcggtgga tagtctggcc aaccggcacc
     7021 cctattcgca tcagtattga taacgccctc gtcgataatg gcgtcatgct cccggaaaac
     7081 accattgaat cggcgtcaat gaacgtcagc accaatttgc tgcaaagcag cgatatgatc
     7141 tctattcttt ctttacggct ggcgcaacgc tatgccagcc aggggcaact ggcgatttta
     7201 aacttgccaa aaattgagca aaaaggcagc gtagggatgt tctggcgtaa gaatgagacg
     7261 ccgtctttgg ccctgagtcg ctttttgtat tttttagccc aggtttaacg ccgccgacca
     7321 ggggcattgc ccgatgttcc tgctgtctat acccactatg ctaagaattc atgatgtgat
     7381 cggtagcacg ttttaacgtt taattgtatg atgaatccat ctcatcaagg gctttaaaca
     7441 tgagtaagtc actgaatatt atctggcaat atatacgcgc ttttgtattg atttatgcct
     7501 gtttgtacgc aggcattttt cttgcatcac tgcttcctat cactattccc ggcagcatta
     7561 tcgggatgtt aattctgttt gtattgctgg cgctgcaaat tctgccggca aagtgggtta
     7621 accccggctg ttatgtgctg attcgttata tggcgttgct gtttgtgcca attggcgttg
     7681 gggtcatgca atattttgac ttactgcgcg cgcaattcgg cccggtggtg gtctcttgcg
     7741 ctatcagtac gctggtcgtt tttgtggtcg taagctggag ttcacatctg atacacggtg
     7801 agcgtaaagt ggttgggcag aagggaacga aaaaatgatg acatatatct ggtggtcgtt
     7861 accgctgacg ctggcggtat ttttcgccgc ccgcagactg gcggcgcatt ttaaaatgcc
     7921 gttgctgaat ccgctgctgg tggcaatggt agtcattatt ccttttctgt tgctgaccgg
     7981 tattccctac gagcactact tcaaaggcag cgaagtactt aacgatctgc tgcaaccggc
     8041 ggtggtggcg ctggcctatc ccctttatga acagttgcac cagattcgcg cgcgttggaa
     8101 atccattatt agcatctgtt ttgtcggcag tctggtagcg atgattaccg gaacatccgt
     8161 tgccttgctg atgggcgcaa cgcctgaaat cgcggcatcg gtactgccta aatccgtgac
     8221 tacgcctatc gcgatggcgg tgggcggcag catcggcggc atccccgcga tcagcgcggt
     8281 atgcgtaatt tttgtcggta ttctgggcgc ggtgtttggc cacacgctgt taaacgcgat
     8341 gcacatccgt actaaagccg cacgcgggct ggcaatgggg accgcctcac atgcgctcgg
     8401 tactgcgcgc tgcgccgagc tggattacca ggaaggcgcg tttagctccc tggcgctggt
     8461 gatctgcggc attattacct cgctggtagc gccctttttg tttccgctca ttctggcggt
     8521 aatgcgctaa cgacgggaca aaagaccggg ttaaaatttg cgatacgtcg cgtatttttc
     8581 atttaagttt cacaagttgc ataagcaatg agatttagat cacatattaa gacatggcag
     8641 gcccgtaaac tacggttcca ttacattgtt atgaggcaac gccatgcatc cacgttttca
     8701 aactgctttt gcccagcttg cggataattt gcaatcagcg ctggccccta tcctggcgga
     8761 ccaccatttt cccgccatgc tgaccgcaga gcaggtctcg acgcttaaaa atacggcggg
     8821 actggacgaa gacgcgctgg ctttcgcact gttacctctg gcggcggcct gcgcccgtac
     8881 cgatttgtcc cattttaacg tcggcgcgat tgcgcgcggc gttagcggca actggtattt
     8941 cggcgcgaat atggagttcc tgggcgccac catgcaacaa actgtgcatg ctgaacaaag
     9001 cgcgattagc cacgcctggc tacgcggcga aaaagggctc gccgccgtca ccgttaacta
     9061 cacgccttgc ggccactgtc gccagtttat gaacgagctg aacagcggtc tggatctgcg
     9121 cattcatctg ccgggccgcg cgccgcatac gttacgcgat tatctgcctg acgctttcgg
     9181 gccaaaagat ctggagatca aaacgctgct gatggacgag caggatcatg gctttacgtt
     9241 aacgggcaat acgctaacgc aagcggcgat tacggcagcc aataagagcc atatgcctta
     9301 tagccactca ccgagcggcg tggcgctgga atgtaaagat ggccgtattt tcaccggcag
     9361 ctatgcggaa aacgccgcct ttaaccctac gcttccccca ctgcaaggcg cgctaaacct
     9421 gctgagtctc aatggctatg actatgcgga tattcagcgc gcgattctgg cggaaaaagg
     9481 cgatgcggca ttaattcaat gggatgccac cgccgcaacg ctgaaagcgt taggttgcca
     9541 taatattgac cgcgtgcttc tcggctaagc aaatgtgccg gatagcgacg cactggcgtc
     9601 ttatccggcc tgactctcct ctcccgcgac ccgatacaag ggaaatcatg ctgaaaatct
     9661 ccgcaatcag acggcggttt cttgcgctac gtcttcgggt acagtagcct gatcgtactt
     9721 tcatcctggt atcgagtttc ctgcatgtta aagcgcgtgt tttacagcct gttggtcctg
     9781 gtaggcttgc tgctgttgac ggtgcttggc ctcgatcggt ggatgagctg gaaaacagcg
     9841 ccctatatct atgacgagct acaggatctc ccctaccgcc aggttggcgt cgtgttaggg
     9901 acagccaaat actatcgcaa gggtgtcatt aatcagtact atcgttatcg tatccagggc
     9961 gcgttaaacg cttacaatag cggtaaagtc aattacctgc tgctcagcgg cgacaatgcc
    10021 ctgcaaagct ataacgaacc gatgaccatg cgcaaagacc ttatcgcggc gggcgtcgat
    10081 cctgcggaca ttgtgcttga ttacgctggc ttccgtacgc ttgactccat tgtgcgtacc
    10141 cgcaaagtgt ttgatatcaa cgactttatt atcatcactc agcgcttcca ctgcgaacgc
    10201 gccttgttta ttgcgttgca tatgggcatt caggcgcagt gttacgcggt accttcaccc
    10261 aaaaatatgc tgacagtacg cttgcgcgaa tttggcgccc gctttagcgc gctggcggat
    10321 ctctatattt ttaaacgcga accgcgtttt ttaggcccgc tggtacctat tcccacgcag
    10381 catcaggtgc caaatgacgc ccaggggtat ccggccgtta cgccggaaca attgcttgaa
    10441 ctggaaaaga aaaaagggaa atgatcatgg atgtacagac gatatttgtc atattagcct
    10501 ttctgctact cccgcttttt tgctttcgtg aggcctggaa aggctggcga accggcgcgg
    10561 tagataaagt tgtcaaaaat gcgcgaaaac cggtttatgt t
//
LOCUS       DAJVBX010000169        10316 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.169, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000169 DAJVBX010000000
VERSION     DAJVBX010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 10316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10316
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.169"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            1..2577
                     /gene="cas3"
                     /locus_tag="OPV72_003529"
                     /pseudo
     CDS             1..2577
                     /gene="cas3"
                     /locus_tag="OPV72_003529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192071.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="CRISPR-associated helicase Cas3'"
     gene            2958..3911
                     /gene="sopD"
                     /locus_tag="OPV72_003530"
     CDS             2958..3911
                     /gene="sopD"
                     /locus_tag="OPV72_003530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system effector SopD"
                     /protein_id="HCR9915731.1"
                     /translation="MPVTLSFGNHQNYTLNESRLAHLLSADKEKAIHMGGWDKVQDHF
                     RAEKKDHALEVLHSIIHGQGRGEPGEMEVNVEDINKIYAFKRLQHLACPAHQDLFTIK
                     MDASQTQFLLMVGDTVISQSNIKDILNISDDAVIESMSREERQLFLQICEVIGAKMTW
                     HPELLQESISTLRKEVTGNAQIKAAVYEMMRPAEAPDHPLVEWQDSLTEDEKSMLACI
                     NAGNFEPTTQFCKIGYQEVQGEVAFSMMHPCISYLLHTYSPFAEFKPTNSGFLKKLNQ
                     DYNDYHAKKMFIDVILEKLYLTHERSLHIGKDGCSRNILLT"
     gene            complement(3999..4733)
                     /gene="cysH"
                     /locus_tag="OPV72_003531"
     CDS             complement(3999..4733)
                     /gene="cysH"
                     /locus_tag="OPV72_003531"
                     /EC_number="1.8.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase"
                     /protein_id="HCR9915732.1"
                     /translation="MSQLDLNALNELPKVDRVLALAETNAQLETLTAEERVAWALENL
                     PGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYQFIDELTDKLKLNLK
                     VYRAGESPAWQEARYGKLWEQGVEGIEKYNEINKVEPMNRALKELNAQTWFAGLRREQ
                     SGSRAHLPVLAIQRGVFKVLPIIDWDNRTVYQYLQKHGLKYHPLWAQGYLSVGDTHTT
                     RKWEPGMAEEETRFFGLKRECGLHEG"
     gene            complement(4809..6521)
                     /gene="cysI"
                     /locus_tag="OPV72_003532"
     CDS             complement(4809..6521)
                     /gene="cysI"
                     /locus_tag="OPV72_003532"
                     /EC_number="1.8.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="assimilatory sulfite reductase (NADPH)
                     hemoprotein subunit"
                     /protein_id="HCR9915733.1"
                     /translation="MSEKYPGPLVVEGKLSDAERMKLESNYLRGTIAEDLNDGLTGGF
                     KGDNFLLIRFHGMYQQDDRDIRAERAAQKLEPRHAMLLRCRLPGGVITTTQWQAIDKF
                     AADNTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSN
                     PYESELHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKT
                     TVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGY
                     LPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGLETFKAEVERRAGITFEPI
                     RPYEFTGRGDRIGWVKGIDDKWHLTLFIENGRILDYPGRPLKTGLLEIAKIHQGEFRI
                     TANQNLIIASVPESQKAKIEKLARDHGLMNAVSAQRENSMACVSFPTCPLAMAEAERF
                     LPSFTDKVEAILEKHGIPDEHIVMRVTGCPNGCGRAMLAEIGLVGKAPGRYNLHLGGN
                     RIGSRIPRMYQENITEPDIQASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPAR
                     DFWE"
     gene            complement(6521..8320)
                     /gene="cysJ"
                     /locus_tag="OPV72_003533"
     CDS             complement(6521..8320)
                     /gene="cysJ"
                     /locus_tag="OPV72_003533"
                     /EC_number="1.8.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent assimilatory sulfite reductase
                     flavoprotein subunit"
                     /protein_id="HCR9915734.1"
                     /translation="MTTPAPLTGLLPLNPEQLARLQAATTDLTPEQLAWVSGFFWGVL
                     NPRSGAVAVTPAPDGKMPGVTLISASQTGNARRVAEALRDDLLAANLNVTLVNAGDYK
                     FKQIASEKLLVIVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDTSYEF
                     FCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRACVVDVLKSRAPVAVPSQSV
                     ATGAVNDIHTSPYTKDAPLTATLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDAL
                     GVWYQNDPALVKELVELLWLKGDEPVMVDGKTLPLAEALEWHFELTVNTANIVENYAT
                     LTRSESLLPLVGDKAQLQHYAATTPIVDMVRFSPAQLDAQALIDLLRPLTPRLYSIAS
                     AQAEVESEVHITVGVVRYDIEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPAN
                     PQTPVIMIGPGTGIAPFRAFMQQRAADGAEGKNWLFFGNPHFTEDFLYQVEWQRYVKE
                     GLLSRIDLAWSRDQKEKIYVQDKLREQGAELWRWINDGAHIYVCGDARRMAADVEKAL
                     LEVIAEFGGMDLESADEYLSELRVERRYQRDVY"
     gene            8756..9118
                     /gene="queD"
                     /locus_tag="OPV72_003534"
     CDS             8756..9118
                     /gene="queD"
                     /locus_tag="OPV72_003534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-carboxytetrahydropterin synthase QueD"
                     /protein_id="HCR9915735.1"
                     /translation="MSTTLYKDFTFEAAHRLPHVPEGHKCGRLHGHSFMVRLEITGEV
                     DPHTGWIMDFADLKAAFKPTYDRLDHYYLNDIPGLSNPTSEVLAKWIWDQVKPVVPLL
                     SAVMVKETCTAGCVYRGE"
     gene            complement(9208..10005)
                     /locus_tag="OPV72_003535"
     CDS             complement(9208..10005)
                     /locus_tag="OPV72_003535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCR9915736.1"
                     /translation="MALRIRVLLENHKGAGTDKSLKARPGLSLLVEDESTSILFDTGP
                     DGSFMQNASAMGIDLSDVSAVVLSHGHYDHCGGVPWLPDNSRIICHPNIARERYAAIT
                     FLGITRKIKKLSCEVDYSRYRMMYTCGPLPIGENFIWSGEIPVVAPEAYGIFGGHDAE
                     PDSILDEGVLIYQSTKGLVIIMGCGHRGIANIVRHCQNITGIKRIYALIGGFHLRCAS
                     PFTLWRVRRFLQEQKPEKLCGCHCTGAWGRLWLPEITAPATGDVLRF"
BASE COUNT         2563 a         2695 c         2523 g         2535 t
ORIGIN      
        1 aatacataat aaaaaacaat acattcaatt catgtaatat attaaaagaa tgtaatatct
       61 caggtacaaa tgcagaaaac tggataatct ggtttcttgc cagccacgat atcggaaaat
      121 tcgccagagg atttcaaaaa tacgccgaat tcccagactc tcccttagtc tctcccatta
      181 gcggtgtttc cgcatttgag agacatgatt ccttaggctt ctatttatgg ggtaaattat
      241 ttgaagcgtg gagttcaggt agtaatgaaa ttatcgcagg cattgaacca gaaaatcgcg
      301 ctaggtttga aagcgcttta aatagctgga tgcttattag caccgggcac catggcatcc
      361 cgccggacac catgaaaaat agaagctcgc tggcattcac cgatgaagac attgtcgcag
      421 caacgcatta tctggaagca ttaagtgaat tattcccttt cactctacct caggaatgga
      481 aaaccaaagc agggagaaaa tgtttaaaac agcacagttg gtttttcgct gggcttgtca
      541 ccctcgccga ctggatgggc tcggatgaaa gccagtttcc actgctcagc agcgccatgc
      601 cattgaaaga ttattggcct ctcgcttgtg aaaaagccca acaggccatc ctccgaatgc
      661 cgccgttatc tcagcacagc cattatcaag atcaccgggc attatttccg ttcattcaga
      721 cgctcacccc tcttcagcaa cgagcaagcg aactggatat ttcagcaccc ggtgcacagc
      781 tggttgtcct ggaagacgtt accggagcag gcaaaacaga ggccgcactg attctgactc
      841 accgcttaat gtcagccaat aaaggccacg gtctctacgt tgggttgccg acaatggcca
      901 ccgcaaacgc catgtatcag cgcctggcat cggcttatca tgcgctattt accgatgagt
      961 ccaggccatc gctcatcctg gcacacggtg ggcgagaaat gtcggactct ttccgacaat
     1021 ccatctggca gccaacagaa aatatagctg aagattatgc ccgtgatgat ggcaacgcga
     1081 ctactgagtg ccatacctgg tttgcagatt cacgcaaaaa agcgctgctg gcggaagtcg
     1141 gcgtaggtac gctggatcaa ctcttaatgg cggtgatgcc ttttcgccat caatcgctcc
     1201 gattgctagg gatgcgcgac aaaatcctgc tgctggatga agtgcacgcc tatgatggtt
     1261 atatggttaa attgctggaa ggtttattgc gcttccatgc cgcccagggc ggtagcgcta
     1321 ttattctgag cgccactctt cccgccgctt tacgggaaaa attacttaat gcgtttagcg
     1381 atggcgcgga atttatgagc gctggtggta gcgataacgc gggttatcca tggttaagcc
     1441 acctcacttc ctccggtctg ttagagcaac cactggccac acgtcccgaa gtccaaagga
     1501 ctgtagccgt taattggata cagcagcgcc aggaagcact ggacattatt tatcgcgttg
     1561 tggcaaccgg acagtgcatt tgttggatcc gcaacacggt tgatgatgcg ctggacactt
     1621 accagcagtt gctacacgag ggaatcgttc cagagcagga tcttttgctt ttccacagcc
     1681 gttttgcttt tatcgatcgt attgctattg aaaataaaac gttaaactgg tttggtaaca
     1741 atgcccccgt ttctgaacga cgtggtaagg tattaatcgc cacacaagtc gttgaacaaa
     1801 gtctcgatct ggactttgac tggatgatca ccgatctggc gccgattgat ttattgatcc
     1861 agcgcgccgg tcgcctgcaa cgccatatcc gcgatgccca tgggcaacga aaatctacgc
     1921 ttccggatga acgccagcca ccagtattgc atatttctgg cccctcactg gcaggagcag
     1981 gcagaagagg gctggttggg gcaagagcta aaaggtaccg gctttgttta caccgatcat
     2041 gcctgcctgt ggcgtaccca ggcgctgctg cgtcaacatg gtgagatccg tatgccggat
     2101 aatgccagag cactcgttga cggcgtatac gagcagaaaa ttgctgcgcc agcaggcttg
     2161 cagacgatct ctgacgttgc ctttggcaaa gtccttagcc aacgttcagt ggctgcgcaa
     2221 aatttattac gttacgatct cggttacgat cgagaagcca gcgacttttt atgggataaa
     2281 gatagagaat tttctacccg tctgggtgaa gagagtgttg atgtttatct cgccagaaaa
     2341 gacattgatg gacagctacg ccctttagtt gatgaaatag atttctgctg ggaaaaaagt
     2401 cgcttatccg tccgaaaatc atggtggcaa aaaaattctg gtacattcca atgtccagat
     2461 gaggaaacat tagcctgttt cagaaaacgc caccatcgcc cttccggaca gattgtgctg
     2521 gtatctgata ccggagaagc tagctattac agtaaacgtt ttggattggt tggataacgg
     2581 gtattattct aactccgttg tatagagaag ttattacatt agattcacta aaatctttgt
     2641 agcttctcta tctatatcca tttccatgaa tacccttaat taaatttaac tacttcattt
     2701 catcatactt tatctctcag catcaacacc atccatgaca aaccaaaatt ttaaaaaaac
     2761 gaccatttgc ggcgaatcat ctaccttttg tctgaattat cgtcaccaca aaggattacc
     2821 aaccataaat gtgctgtatt gataatgccg ttcacattct ctcctgtagt aaaccttgtc
     2881 tgtttaataa aaaagagcga attgaacgat atattttact ccggatattg aataatataa
     2941 atttgaagga aaatattatg ccagtcactt taagcttcgg taatcatcaa aattatacgc
     3001 ttaatgaaag tcggcttgct catctgttaa gcgcagataa agaaaaagca atccatatgg
     3061 ggggctggga taaagtccag gatcatttta gagcggaaaa aaaggaccat gcgctggaag
     3121 tgttacactc catcattcac gggcagggcc gtggtgaacc tggagagatg gaagttaacg
     3181 tagaggatat caataaaatt tacgccttta aacggctaca acatctggcc tgcccggctc
     3241 atcaggatct gtttactatc aagatggacg cttctcagac acaattttta cttatggtcg
     3301 gcgacacggt gatcagccaa agcaatatta aggacatcct caatatatca gatgatgcag
     3361 tgatagaatc tatgagtaga gaagagagac agttattttt acaaatatgc gaggtgattg
     3421 gtgcgaagat gacctggcac ccggaattac ttcaggagtc gatttctact ctacgaaaag
     3481 aagtgacggg caatgcacaa atcaaagcgg cggtttatga gatgatgcgt cccgcagagg
     3541 ctccagacca cccgcttgtc gaatggcagg actcgcttac tgaagatgaa aaatcgatgc
     3601 tggcctgtat taatgccggt aactttgagc ctacaactca gttttgcaaa ataggttatc
     3661 aggaggtaca aggtgaagtc gcttttagca tgatgcatcc gtgcatctcc tatttactac
     3721 atacctattc accgtttgca gagtttaaac caacaaattc cggtttttta aaaaaactta
     3781 atcaggatta taacgactac catgcaaaaa aaatgtttat tgatgtaatt cttgaaaagc
     3841 tatatctaac gcatgaacgt tctttgcaca ttggtaaaga tgggtgcagt cgtaatatat
     3901 tactgacata aagatagcca gtaatataac caatttaaaa tccggctgcc tgccggattt
     3961 tacatagcag caagtataat cataccgcgt aaggacaatt acccttcatg cagcccgcac
     4021 tcacgtttca gtccgaagaa gcgtgtctct tcttccgcca tacccggctc ccatttgcgg
     4081 gtggtgtgcg tatcgcccac cgacagatag ccctgagccc acagcggatg gtatttcaga
     4141 ccgtgctttt gcagatactg gtaaaccgtg cggttatccc agtcgataat cggtagcact
     4201 ttaaacacgc cgcgctggat agcgagaacg ggtaaatgcg cgcggctacc ggactgctcg
     4261 cgacgcagac ccgcaaacca ggtctgcgcg tttaactctt tgagcgcccg gttcatcggc
     4321 tcgactttgt tgatctcatt gtatttctca atgccctcaa cgccctgctc ccacagcttg
     4381 ccgtagcgcg cttcctgcca ggccggactt tcgcccgcgc ggtaaacttt caggttgagt
     4441 ttgagtttgt ccgttagctc atcaataaac tgataggttt ccgggaacaa atagccggta
     4501 tcggtgagga tcaccgggat atccgggcga atctggttca ccaggtgcag gctcaccgcc
     4561 gcctggatac caaagcttga ggagagcacg tattcgccgg gcagattttc cagcgcccaa
     4621 gccacgcgtt cttcggcagt cagcgtttcc agttgagcgt tggtttccgc caacgccagt
     4681 acgcgatcga cttttggcag ttcattcaat gcgttgagat cgagttggga cataagttcc
     4741 tcactgtttg ccttgcctga tggcgctgtg cttatcaggc ctacacagac gccatccggc
     4801 aattcaggtt attcccagaa atcacgcgcg ggatcgagca ccgggcgaat gatgcccgca
     4861 cgcaccgtaa agtcgccgaa gccttcaccc gcttcacgct ctttcgccca gcgcccaatc
     4921 agttcatcca gcgaagcctg aatatccggc tcggtgatat tttcttgata catccgtgga
     4981 atacgactcc cgatgcggtt gccgccaaga tgcaggttat aacgaccagg cgctttccct
     5041 actaagccaa tttccgccag catcgcgcga ccacagccgt tcgggcagcc ggtcacgcgc
     5101 atcacgatat gctcatcagg aatgccgtgt ttttccagaa tcgcttccac tttgtcagta
     5161 aacgacggta ggaaacgctc ggcttccgcc atcgccagcg ggcaggtcgg gaacgacacg
     5221 caggccattg agttttcacg ctgcgcgctc accgcattca tcagcccatg atcgcgcgcc
     5281 agtttctcga tcttcgcttt ctggctttcc ggcacgctgg caataatcag gttctggtta
     5341 gcggtaatac ggaactcgcc ctgatgaatc ttcgcgatct ccagcaggcc ggttttcagc
     5401 ggacgccccg gatagtccag gatacgaccg ttttcgataa acagcgtcag gtgccattta
     5461 tcatcaatgc ctttcaccca gccaatcctg tcgccacgcc cggtaaattc atacggacga
     5521 atgggttcaa atgtgatccc cgcgcgacgc tcgacttccg ctttaaacgt ctccagtccc
     5581 acacgctcaa gggtgtattt ggttttggcg tttttacggt cggtacggtt accccagtcg
     5641 cgctgcgtag tcaccaccgc ttccgccacc gccagggtgt gctccagcgg cagatagcca
     5701 aactcgctcg cggtacgagc gtaggttttc ttattaccgt gctcaataga cagaccgccg
     5761 cccaccagca ggttaaagcc gaccagcttg ccgttctcgg caatcgccac gaagttcatg
     5821 tcgttggcgt gcagatcgat atcgttttgc ggcgggatca ctaccgtggt tttgaactta
     5881 cgcggcagat aggtctgtcc gaggatcggc tcttcatcgg tggtcgccac cttctcctga
     5941 tcgagccaga tctccgcata cgcacgagtg cgcggcagca gatgttcgga gatcttcttc
     6001 gcccattcgt aggcttccgc gtgcagctcg gactcatacg ggttagaggt acacagcacg
     6061 ttacggttca tatcgttggc ggtcgccagc gcgtccagcc ccaccgaatg cagcatctgg
     6121 tgcaccggct taacgttctt cttcagaata ccgtggaact ggaaggtctg acggttggtc
     6181 agacggatac tgccataaat cgtgttatcc gccgcgaatt tatcgatcgc ctgccattgc
     6241 gtcgtagtaa tcaccccgcc cggcaggcgg cagcgcagca gcatggcgtg gcgcggctcc
     6301 agcttctgcg ccgcacgctc ggcgcgaata tcgcggtcat cctgctgata catgccatga
     6361 aagcgtatta gcaggaagtt gtcgccttta aaaccgccgg tgagaccgtc gttcagatct
     6421 tccgcaatgg taccgcgcag gtagttgctt tccagcttca tgcgctcggc atcggacagt
     6481 ttaccttcga ccaccagtgg gcctggatat ttttcgctca ttagtagaca tctcgctgat
     6541 aacggcgctc tacgcgcagc tcacttaaat attcatctgc cgattcgagg tccataccgc
     6601 cgaattcagc gatcacttcc agcaatgctt tttcgacatc tgcggccatg cgcctggcgt
     6661 cgccgcagac ataaatgtgg gcgccatcat tgatccagcg ccacagctcc gcgccctgtt
     6721 cacgcagctt gtcttgtacg taaatttttt ctttttgatc gcgggaccag gcgagatcga
     6781 tacggcttaa cagtccctct ttcacgtagc gctgccactc cacctgatag aggaaatctt
     6841 cggtaaagtg cgggttgccg aagaacagcc agttcttgcc ttccgcgcca tcggcggcac
     6901 gctgttgcat aaaggcgcgg aacggcgcga tgccggtgcc ggggccaatc atgatcaccg
     6961 gcgtttgcgg gttcgctggc aggcggaagt tatcgttatg ctcaataaag acgcgaactt
     7021 cgccctcttc ttccacgcgg tcggcgagga agctggaagc gccacccgcg cgggcgcggc
     7081 cttcgatatc atagcgaacc acgccaacgg tgatatgcac ttcactctcc acttcagcct
     7141 gtgcggaggc gatggagtac agacgcggcg tcagcgggcg cagcaggtcg attagcgcct
     7201 gagcatccag ctgcgccgga gagaaacgca ccatatcaac gatcggcgtg gtcgcggcgt
     7261 aatgctggag ctgcgctttg tcacccacta atggcaacag cgactcactg cgcgtcaggg
     7321 tcgcgtagtt ctcaacaatg ttggcggtat tcaccgtcag ctcgaagtgc cactccagcg
     7381 cttcggcgag cggcagggtt ttaccatcaa ccatcaccgg ctcatcgcct ttcagccaca
     7441 gcaactcaac cagttccttc accagagccg gatcgttctg ataccagacg cccagcgcat
     7501 cgcccggctg gtaacgcaga ccggagtcgc ctaaatcaat ctcaatatga cgaacgtctt
     7561 tttccgagtt gcgaccggtg attttctgat tcacggagag ggtcgcggtc agcggcgcgt
     7621 ctttggtata ggggctggtg tggatgtcgt ttaccgcgcc agtagcgacg gattgcgaag
     7681 gtaccgcgac aggtgcacgg gacttcagaa catcaaccac gcaggcgcgc cattcgctgg
     7741 cagctgcctg atattcaacg tcagcatcga cacggtcgag cagacgctca ccgcccagtt
     7801 ccgccagttt gctgtcgaaa tcttttccgg actggcagaa aaattcataa gaggtgtcgc
     7861 cgaggctaaa cacggcaaaa gcggtgtttt ctagtttcgg cgcttttttc gagaacagga
     7921 acttatgcag cgcgacagcc tcttccggcg gctcgccttc tccctgggtg gacgtcacta
     7981 tcaccaacag tttttcactg gcaatctgtt tgaatttgta gtcgccggcg ttcaccagag
     8041 tcacattaag gttggccgcc agcagatcat cacgcagcgc ttccgccaca cgacgcgcat
     8101 tgccggtttg cgaagcggag ataagcgtaa ctcccggcat cttcccatca ggagcaggcg
     8161 tgacggcaac agcgcctgag cgcgggttca gtacgcccca aaaaaagccg gagacccagg
     8221 caagctgttc gggagtaagg tcggttgtcg cggcctgaag gcgcgccagt tgctccggat
     8281 taagcggaag caacccagtc agtggagccg gtgtcgtcat gcgtcgttat gttccagtaa
     8341 gcaaagcgga tctatacaca aaatcattca agttcgctgt agcccagact gtaagctgat
     8401 cgcgccccag gagcgtacat aaatacgtga ctggggcgag taaacgcagt caacacaaat
     8461 gcggcttgaa ggatgaagtg tataagcgat aaatcccaaa ctaaggataa gggtaacggt
     8521 gagaggaata acaattaaag aagggttgga aataacaaat aaccaaatga actaacctgt
     8581 tttagttatc gttattaacg ccaaaatcga tttcataatt gattgataat tattaaattt
     8641 tctggaaatt cttaaattaa ttgcccgtta caaggcggag aatggtttta gttaatgata
     8701 aaaaatgcgc tttccggtac cctacagcgg tttttttatt gcctgagagt tcatcatgtc
     8761 caccacgttg tataaagatt tcacctttga agccgctcac cgcctgcctc acgtgcctga
     8821 agggcataag tgcggccgcc tgcacggaca ctcatttatg gtgcgtctcg agattaccgg
     8881 tgaagtcgat ccgcataccg gttggattat ggatttcgcg gatctcaaag cggcgtttaa
     8941 acctacttac gatcgtcttg atcactacta tctgaatgat attccaggac tgtccaatcc
     9001 caccagcgaa gtgctggcaa aatggatttg ggatcaggtt aagcccgtcg tgccgctact
     9061 gagcgccgtg atggtgaaag agacctgtac agccggctgc gtctatcgcg gcgaataagg
     9121 tttattaacg cgtgggctgg atggtaaatt gattccagcc tatccacacg acgttttatc
     9181 agtgaaaaca ttgcccagcg cgcggtgtta aaagcgcagc acatcaccgg ttgcaggtgc
     9241 ggttatttcc ggtagccaca accgccccca ggccccggta cagtgacaac cgcatagttt
     9301 ttcaggtttt tgttcttgca gaaagcgcct gactcgccac agcgtgaacg gtgatgcgca
     9361 gcggagatga aatccgccga taagcgcgta aatccgcttt ataccggtaa tgttctgaca
     9421 gtgccggaca atatttgcga tcccccgatg cccgcatccc ataatgatga ctaatccttt
     9481 tgtcgattgg taaatcagta cgccctcatc caaaatagag tccggctccg catcgtggcc
     9541 gccaaaaatg ccgtaggctt caggcgcgac caccggtatt tcccctgacc agataaagtt
     9601 ttcgccaatc ggcagggggc cacacgtgta catcattcgg tagcgtgaat agtccacctc
     9661 acacgacaat ttttttattt tccgggtaat accgagaaaa gttattgccg cataacgttc
     9721 gcgcgcaata ttgggatggc agatgattcg actgttatca ggaagccacg gcacgccgcc
     9781 gcaatgatcg taatgaccat gcgaaagcac cacagcagac acatcggaca ggtcgatccc
     9841 catcgccgac gcgttttgca taaaactgcc atcagggccg gtatcgaaca agatcgacgt
     9901 agactcatcc tcgaccaaca ggcttaatcc tggccgggcc ttcaacgatt tatccgttcc
     9961 agctccctta tgattttcga gcaataccct gatccttaac gccatggcct tctcctgtat
    10021 aaaagcctcc ccgggaaaac gcggcctttt tactttacag gtttgtagca gccattactg
    10081 gtacacagat tatgattatg caacggctat ccttgttgac gtggggaata ctgctacacg
    10141 caaaaattcc agtcgttggc gcacggttta tccccgctgg cgcggggaac acactaaacg
    10201 tatatcattg tttataaact actttttatt agcaccacat tctaccaaca taatagcaac
    10261 aatttaaatt attaaagaac agctaatttg ctgattttga tgcaaaaaag ttcata
//
LOCUS       DAJVBX010000170        10299 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.170, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000170 DAJVBX010000000
VERSION     DAJVBX010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 10299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10299
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.170"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            341..1681
                     /gene="dcuB"
                     /locus_tag="OPV72_003536"
     CDS             341..1681
                     /gene="dcuB"
                     /locus_tag="OPV72_003536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic C4-dicarboxylate transporter DcuB"
                     /protein_id="HCR9915737.1"
                     /translation="MLFSIQLLIILICLFYGARKGGIALGLLGGIGLVILVFVFHLQP
                     GKPPVDVMLVIIAVVAASATLQASGGLDVMLQIAEKLLRRNPKYVSIVAPFVTCTLTI
                     LCGTGHVVYTILPIIYDVAIKNNIRPERPMAASSIGAQMGIIASPVSVAVVSLVAMLG
                     NVTFDGKHLEFLDLLSITIPSTLLGILAIGIFSWFRGKDLDKDEAFQKFISVPENRQY
                     VYGDTATLLDKKLPKSNWLAMWIFLAAIAVVALLGADSDLRPTFGGKPLLMVLVIQMF
                     MLLTGALIIILTKTNPASISKNEVFRSGMIAIVAVYGIAWMAETMFGAHMSEIQGVLG
                     EMVKEYPWAYAIVLLLVSKFVNSQAAALAAIVPVALAIGVDPAYIVASAPACYGYYIL
                     PTYPSDLAAIQFDRSGTTRIGRFVINHSFILPGLIGVSVSCVFGWIFAAMYGFL"
     gene            1777..3423
                     /locus_tag="OPV72_003537"
     CDS             1777..3423
                     /locus_tag="OPV72_003537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I fumarate hydratase"
                     /protein_id="HCR9915738.1"
                     /translation="MSKKEFIYQAPFPMGEDKTEYYLLTSDYVSVSEFNGESILNVEP
                     QALTLLAQQAFHDASFMLRPEHQQQVAAILHDPEASENDKYVALQFLRNSEIAAKGIL
                     PTCQDTGTAIIMGKKGQRVWTGGGDEAALSKGVFNTYIEDNLRYSQNAPLDMYKEVNT
                     GSNLPAQIDLYAVDGDEYKFLCVAKGGGSVNKTYLYQETKALLTPGKLKNFLVEKMRT
                     LGTAACPPYHIAFVIGGTSAESTLKTVKLASTHYYDALPTEGNEHGQAFRDLHLEQEL
                     LEEAQKLGLGAQFGGKYFAHDIRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIW
                     IEKLEHNPGQYIPPALRQAGEGDAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVG
                     RDIAHAKLKERIESGEDLPQYIKDHPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDL
                     LQSHGGSMIMLAKGNRSQQVTDACKKHGGFYLGSIGGPAAVLAQQSIKHLECVEYPEL
                     GMEAIWKIEVEDFPAFILVDDKGNDFFQQIVSKQCANCAK"
     gene            complement(3521..4951)
                     /gene="melB"
                     /locus_tag="OPV72_003538"
     CDS             complement(3521..4951)
                     /gene="melB"
                     /locus_tag="OPV72_003538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="melibiose:sodium transporter MelB"
                     /protein_id="HCR9915739.1"
                     /translation="MSISLTTKLSYGFGAFGKDFAIGIVYMYLMYYYTDVVGLSVGLV
                     GTLFLVARIWDAINDPIMGWIVNATRSRWGKFKPWILIGTLTNSLVLFLLFSAHLFEG
                     TAQVVFVCVTYILWGMTYTIMDIPFWSLVPTITLDKREREQLVPFPRFFASLAGFVTA
                     GITLPFVNYVGGADRGFGFQMFTLVLIAFFIASTIVTLRNVHEVYSSDNGVTAGRPHL
                     TLKTIVGLIYKNDQLSCLLGMALAYNIASNIINSFAIYYFTYVIGDADLFPYYLSYAG
                     AANLLTLIVFPRLVKMLSRRILWAGASVMPVLSCAGLFAMALADVHNAALIVAAGIFL
                     NIGTALFWVLQVIMVADTVDYGEFKLNIRCESIAYSVQTMVVKGGSAFAAFFIALVLG
                     LIGYTPNVAQSAQTLQGMQFIMIVLPVLFFMMTLVLYFRYYRLNGDMLRKIQIHLLDK
                     YRKTPPFVEQPDSPAISVVATSDVKA"
     gene            complement(5035..6390)
                     /gene="melA"
                     /locus_tag="OPV72_003539"
     CDS             complement(5035..6390)
                     /gene="melA"
                     /locus_tag="OPV72_003539"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HCR9915740.1"
                     /translation="MMTAPKITFIGAGSTIFVKNILGDVFHREALKSAHVALMDIDET
                     RLEESHIVVRKLMDSAGASGRITCHTHQKAALQDADFVVVAFQIGGYEPCTVTDFEVC
                     KRHGLEQTIADTLGPGGIMRALRTIPHLWQICEDMTEVCPKATMLNYVNPMAMNTWAM
                     YARYPHIKQVGLCHSVQGTAEELARDLNIDPASLRYRCVGINHMAFYLELERKTADGT
                     YVNLYPELLAAYDAGQAPKPNIHGNERCQNIVRYEMFKKLGYFVTESSEHFAEYTPWF
                     IKPGREDLIARYKVPLDEYPKRCVEQLANWHKELEEYKTAERIDIKPSREYASTIMNA
                     LWTGEPSVIYGNVRNEGLIDNLPQGSCVEVACLVDANGIQPTKVGTIPSHLAAMMQTN
                     INVQTLLTEAILTENRDRVYHAAMMDPHTAAVLGIEEIYALVDDLIAAHGDWLPAWLR
                     R"
     gene            6659..7591
                     /gene="melR"
                     /locus_tag="OPV72_003540"
     CDS             6659..7591
                     /gene="melR"
                     /locus_tag="OPV72_003540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator MelR"
                     /protein_id="HCR9915741.1"
                     /translation="MSTQAISLLPPDPHMCNGDEKQTRSPLSLYSEYQRLDVELRPPH
                     RMASSHWHGQVEVNVPFDGDVEYLINNEVVQIKQGHITLFWACTPHQLTRPGNCRQMA
                     IFSLPMHLFLSWPLDRDLINHVTHGMVVKSLATQQLSTFEVLRWQQETSSPNEQIRQL
                     AIDEIGLMLKRFSLSGWQPILLNKTSRTHKNSVSRHAQFYVSQMLGFIADNYDQALTI
                     NDVAEHVKLNANYAMGIFQRVMQLTMKQYITAMRINHVRALLSDTDKTILDVALTAGF
                     RSSSRFYSTFSKFVGMSPQQYRKLSQQRRQTMPG"
     gene            7824..10091
                     /gene="adiA"
                     /locus_tag="OPV72_003541"
     CDS             7824..10091
                     /gene="adiA"
                     /locus_tag="OPV72_003541"
                     /EC_number="4.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709824.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine decarboxylase"
                     /protein_id="HCR9915742.1"
                     /translation="MKVLIVESEFLHQDTWVGNAVERLADALSQQNVTVIKSTSFDDG
                     YAILSANEAIDCLMFSYQMEQPDEHLSVRQLIGKLHERQQNVPVFLLGDREKATASLD
                     RDLLELVDEFAWILEDTADFIAGRAVAAMTRYRQQLLPPLFNALMKYSDIHEYSWAAP
                     GHQGGVGFTKTPAGRFYHDYYGENLFRSDMGIERTTLGSLLDHTGAFGESEKNAARVF
                     GADRSWSVVVGTSGSNRTIMQACMTDNDVVVLDRNCHKSIEQGLILTGAKPVYMVPSR
                     NRYGIIGPIYPQEMQPETLQKKISASPLTKTKAGQKPSYSVVTNCTYDGVCYNAKEAQ
                     DLLAKTSDRIHFDEAWYGYARFNPIYCDHYAMRGEPGDHNGPTVFATHSTHKLLNALS
                     QASYIHVREGRGAVNFSRFNQAYMMHATTSPLYAICASNDVAVSMMDGNSGLSLTQEV
                     IDEAVDFRQAMARLYKEFTDEGDWFFKPWNKDVVTDPQTGKTYDFADAPAKLLATDQN
                     CWVMRPGETWHGFKDLPDNWSMLDPIKVSILAPGMGDDGELEASGVPAALVTAWLGRH
                     GIVPTRTTDFQIMFLFSMGVTRGKWGTLINTLCSFKHHYDANTPLAQVMPELVQDYPD
                     TYANMGIHDLGDKMFAWLRENNPGARLNAAYSTLPVAEITPRDAYNAIVNNNIEMVAI
                     ENLPGRIAANSVIPYPPGIPMLLSGENFGDENSPQVGYLRSLQSWDHHFPGFEHETEG
                     TEIIDGVYHVMCVKA"
BASE COUNT         2506 a         2826 c         2637 g         2330 t
ORIGIN      
        1 acaatgatca cataagtcac attctgttca atttatctcg tgatttacct gatggcgaga
       61 cacaaaaatt aaataataaa cgcctgtttt taaaacagac aaatcataat ttactgctct
      121 cgctgactcc acctgcccat cgccagaggg tgcttccctc tgaacatcac catcgcaaga
      181 aaataattac ttaaagcaac tctgtaaaaa gcttaatcgt taatcgtcgc cactgacgca
      241 ttgaatattc gccatttcct gatgctcatt cacacaaatc agaagatggc tgtgatccat
      301 ttatcaaaat tgactgggtt tatcgcgagg ataaataaaa atgttattta gtatacagct
      361 tctcataata ttaatatgtc tgttttatgg tgcccgaaag ggcgggatcg cgctcgggtt
      421 gttgggcggt atcggtctgg tcattctggt gtttgttttc catctccagc caggtaaacc
      481 gcccgttgac gtaatgctgg tcattatcgc ggtagtcgcc gcgtcggcga cgttgcaggc
      541 gtcaggcggg ctggatgtga tgttgcagat tgccgaaaag ctgctgcgcc gcaaccccaa
      601 atacgtctct attgtggcgc cgttcgtcac ctgtaccctg acgattctgt gtgggacagg
      661 ccacgtggtt tacaccattt tgccgattat ctatgacgtg gcgatcaaga ataatatccg
      721 tccggaacgt ccaatggcgg ccagttctat cggcgcgcaa atgggtatca tcgccagtcc
      781 ggtttccgtc gccgtggttt ctctggtagc gatgctgggc aacgtgacat ttgacggaaa
      841 acatctggag ttcctcgatc tgctgtcgat caccatcccg tctaccctgc tcggtatcct
      901 ggcaatcggt atttttagtt ggttccgcgg taaagatctg gataaagacg aagcgtttca
      961 gaaatttatc tccgtaccgg aaaaccgtca gtacgtgtac ggcgataccg cgacgctgct
     1021 ggataaaaaa ctgccgaaaa gcaactggct ggcgatgtgg atcttcctgg cggcgattgc
     1081 cgtggtcgct ctcctgggcg cggactccga cttacgtcca accttcggcg gcaaaccgtt
     1141 gttgatggtg ctggtcattc agatgttcat gctgctgacc ggggcactca ttatcattct
     1201 gaccaaaacc aatcctgcgt ctatctcaaa aaacgaagtt tttcgttccg gtatgattgc
     1261 gattgtcgcg gtatacggga tcgcctggat ggcggaaacc atgttcggcg cgcatatgtc
     1321 ggaaattcag ggcgtgctgg gcgaaatggt caaagagtat ccgtgggcct acgccatcgt
     1381 tctgctgctg gtctccaagt ttgttaactc ccaagcagcg gcgctggcgg cgattgttcc
     1441 cgtcgcgctg gctatcggtg tcgatccggc gtatatcgtg gcctctgcgc cggcatgtta
     1501 tggctactat atcctgccga cctacccaag cgatctggcg gcgattcagt ttgaccgttc
     1561 cggcacaacc cgtattggtc gcttcgtcat taaccacagc ttcattctgc cgggtttgat
     1621 tggcgtgagc gtctcctgcg tctttggctg gatctttgcc gcaatgtacg gattcctgta
     1681 atggccgcgc gcgccgcccg gctatgcgcg gcgcgcgact tagagcctgg cccatgaggc
     1741 tcttaataca ttttcttact attaggctgg aagcacatgt cgaaaaaaga gtttatctat
     1801 caggcgcctt tcccgatggg agaggacaaa acagagtatt atctgctcac ctccgattat
     1861 gtcagcgtca gtgaattcaa tggagaatct atcctcaacg ttgagccgca ggcgttaacg
     1921 ttgctggctc agcaggcttt ccatgatgcg tcttttatgc tccgtcctga acaccagcag
     1981 caagtcgccg ccattctcca tgaccccgaa gccagcgaaa acgacaaata tgtggcgttg
     2041 caattcctga gaaactccga gatcgccgcc aaaggcattc tgccgacctg ccaggatacc
     2101 ggcacggcga ttatcatggg taaaaaaggc caacgcgtct ggacgggcgg cggcgatgaa
     2161 gccgcgctct ccaaaggcgt gtttaatacc tatatcgaag ataacctgcg ctactcgcag
     2221 aacgcgccgc tggatatgta caaagaggtc aataccggca gcaacctgcc agcgcaaatc
     2281 gatctctatg ccgtcgatgg cgacgagtac aagttccttt gcgtggcgaa aggcggcggt
     2341 tcagtaaaca aaacgtatct ctatcaggag accaaagcgc tgctcacccc aggcaagctg
     2401 aaaaacttcc tcgttgagaa aatgcgcacg ctgggcaccg cggcctgtcc gccataccat
     2461 atcgcctttg tcattggtgg cacctcggcg gaaagcacgc tgaaaaccgt taaactcgcc
     2521 agcacccact attacgacgc gctgccgacg gaaggtaacg agcacggcca ggcattccgc
     2581 gatctccacc tggaacagga actgctggaa gaagcgcaaa aacttggcct cggcgcccag
     2641 ttcggcggga aatatttcgc ccacgatatt cgcgtaattc gcctgccgcg tcacggcgct
     2701 tcctgtccgg tggggatggg cgtctcctgc tcggcagacc gtaacatcaa agcgaaaatc
     2761 aaccgcgaag gcatctggat cgaaaaactg gaacacaatc cgggccagta tattccgcca
     2821 gcgctgcgtc aggcgggcga aggcgacgcg gtgaaagtcg atcttaaccg tccgatgaaa
     2881 gagatcctcg cccagctatc gcagtacccg gtctcgactc gcctgtcgct gacgggcacc
     2941 attatcgtag gtcgcgatat cgcccacgcg aagctaaaag agcgtattga atccggcgaa
     3001 gacctgccgc agtatattaa agaccacccc atctattacg caggtccggc caaaaccccg
     3061 gcaggttatc catctggctc attaggcccc accaccgcag gccgaatgga ctcttatgtc
     3121 gatctactgc aatcccacgg cggcagtatg atcatgctgg cgaaaggcaa ccgtagtcag
     3181 caggtcacgg atgcctgtaa aaaacacggc ggcttttatt tgggcagtat cggcggcccg
     3241 gcggcggtac tggcacagca gagcattaag catctggagt gcgtcgagta tccggaactc
     3301 ggcatggaag ctatctggaa aattgaagta gaagatttcc cggcctttat tctggtggat
     3361 gacaaaggca acgatttctt ccagcagatt gtcagcaaac agtgcgctaa ctgcgcgaaa
     3421 taacctggca ggcccggcgt tctcccgggc cgcgttatcg gttaattgcc ggatggcgct
     3481 acgcttatcc ggcttatccg gcctgcacga gagaccatgc tcacgctttt acatcgctgg
     3541 tcgctaccac agaaatcgcc gggctatccg gctgttcgac gaatggcggc gttttccggt
     3601 atttatccag caggtggatc tgaatcttgc gcagcatatc gccgttcaaa cggtagtagc
     3661 ggaagtagag aaccaacgtc atcatgaaaa acagtaccgg caggacaatc ataataaact
     3721 gcatcccctg cagggtttgc gcagactgcg ccacgttcgg cgtgtagcca atcagcccca
     3781 gcaccagagc gataaagaac gccgcaaacg ccgagccgcc cttcacaacc atcgtctgta
     3841 cggaataagc gatactctcg cagcgaatat tgagcttaaa ttccccataa tcgaccgtat
     3901 ccgccaccat gattacctga agcacccaaa agagcgcggt cccgatattc aggaaaatac
     3961 ccgccgccac gattaaagcg gcattatgga catccgccaa cgccatcgcg aagagccctg
     4021 cgcaactcag aacgggcatc acggaggcgc ccgcccacaa tatccgccgc gataacattt
     4081 tcaccagccg ggggaagaca atcagcgtca gcagattcgc cgcgccggcg taagaaaggt
     4141 aatagggaaa aagatcggca tcgccaatca cataggtgaa gtagtagatc gcaaagctat
     4201 tgataatatt ggaggcgatg ttatacgcca gcgccattcc caacaggcaa gagagctgat
     4261 cgtttttgta tatcaatcca acgatcgttt ttaacgtcag atgtgggcgg cccgccgtta
     4321 caccgttgtc ggaggagtac acctcatgta cgttgcgtaa tgtcacgata gtcgaggcga
     4381 taaagaacgc aatcagtacc agcgtaaaca tctgaaagcc gaacccacga tccgccccgc
     4441 caacatagtt cacaaacggc agcgttatac cggcagtgac gaagccagcc agactggcga
     4501 agaaacgcgg gaacggcacc agttgttcgc gttctcgctt atcaagcgta atggtcggca
     4561 ccagcgacca aaatgggata tccataatgg tatacgtcat gccccacagg atgtaggtta
     4621 cgcagacaaa tacaacctgc gcggttccct caaaaagatg ggcgctgaac agcaggaaaa
     4681 gcaccagcga attggttaag gtgccgatca atatccacgg cttaaatttc ccccaccgcg
     4741 aacgcgtggc gttgacaatc cagcccatga tgggatcgtt tatcgcatcc caaattcgcg
     4801 cgaccagaaa gagggtgccg acgaggccga ccgagagtcc caccacatcg gtgtagtaat
     4861 acatcaggta catatacaca atgccgatgg cgaaatcctt accaaacgca ccgaacccgt
     4921 aactcagctt tgttgtcaga gagatgctca tagggtaccg ggtcgctgtt accagcgccc
     4981 gccttctgtt agtagaggtt aaacgccgga tctgccgtcc agcgcggctg gagattaacg
     5041 gcgtaaccag gccggaagcc agtcgccatg cgcggcgatc agatcgtcaa ccaacgcata
     5101 gatttcttcg atacccagca ccgccgcggt atgagggtcc atcatcgccg cgtgatacac
     5161 gcgatcgcgg ttttccgtga ggatggcttc ggtcaacagc gtttgcacgt tgatgttggt
     5221 ctgcatcatt gccgccagat gggaagggat cgtccccacc ttcgtcggtt gaatgccgtt
     5281 ggcatctacc agacaagcca cctcgacgca gcttccctgc ggcaggttat caatcagtcc
     5341 ctcattacgc acattgccgt aaatcacgct cggctcgccg gtccacagag cgttcataat
     5401 ggtgctggcg tactcgcggg acggtttgat gtcgatacgc tcggcggttt tatactcctc
     5461 cagctcttta tgccagttcg ccagttgttc tacgcagcgt ttcggatatt catccagcgg
     5521 caccttgtag cgcgcaatca gatcctcgcg tcccggttta ataaaccacg gcgtgtactc
     5581 ggcaaaatgc tctgatgact ccgtgacgaa gtagcccaac tttttgaaca tctcatagcg
     5641 cacgatgttc tggcagcgtt cattgccgtg aatattgggc ttcggcgcct gtccggcgtc
     5701 ataagccgcc agcaattcag gatagagatt gacataagtc ccgtcagccg ttttgcgctc
     5761 cagttccagg taaaacgcca tgtggttaat gccgacgcag cggtagcgca gcgaggcggg
     5821 atcgatattc aagtcgcgcg ccagttcttc cgccgttccc tgtaccgaat ggcacaggcc
     5881 gacctgtttg atatgcggat agcgggcata catcgcccag gtattcatcg ccatcgggtt
     5941 gacgtaattg agcatggtgg ccttcggaca gacttccgtc atgtcttcgc aaatctgcca
     6001 cagatgcggg atggttcgca gcgcgcgcat gatgccgccc ggccccagcg tatcggcgat
     6061 cgtctgttcc aggccatgac gcttacaaac ctcaaaatcg gtcacggtgc agggttcata
     6121 gccgccaatc tgaaaggcga ccaccacgaa atccgcatcc tgtagcgccg ctttctggtg
     6181 ggtatggcag gtaatccggc cagaagcgcc cgctgagtcc atcagtttcc gtaccacaat
     6241 gtgcgactct tccagccggg tttcgtcaat atccatcagg gcgacatgcg ctgactttag
     6301 cgcctcgcgg tgaaacacat cgccgaggat atttttgacg aaaatcgtag aacctgcgcc
     6361 gataaaggta attttgggtg ccgtcatcat gactctccag aacagtagtg aacaccttca
     6421 tggtggcacg cgttcccggt gaaaacctcc gtcttccccg atgagcattc ccgaaaactc
     6481 agatcgtatg ctggcgcgcg ggagatctga gtttttggga caaaatggcg taaaaagcag
     6541 agtattcggc ctgatagtca ggctacgctc tacaatatcg acggattctg tgtccggatt
     6601 cccggtttcc tcccggctaa aggggcataa ttctgataat tcaggaaatg gagtgacgat
     6661 gagtacgcaa gcaatatccc tcctcccgcc cgacccgcac atgtgcaacg gcgatgaaaa
     6721 gcaaacccgt agcccgctgt cgctctattc cgaatatcaa cgactggacg ttgagctgag
     6781 gccgccgcac agaatggcca gcagtcactg gcatgggcaa gtagaagtga atgttccgtt
     6841 tgacggcgat gtggagtatt taatcaacaa tgaagtcgtg cagataaagc agggacatat
     6901 caccctgttt tgggcctgta cgccacacca gcttacccgc cccggcaact gccgccagat
     6961 ggcgattttc agtttgccga tgcacctgtt tctctcctgg ccgctggatc gcgatcttat
     7021 caaccatgtc acgcacggga tggtggttaa atcactggcg acccagcagc ttagcacctt
     7081 tgaagtgttg cgctggcagc aggaaacaag cagcccgaat gagcaaattc gccagttggc
     7141 gatcgatgaa atcggcttga tgcttaaacg ctttagcctt tccggctggc aacccatttt
     7201 gctcaataaa acatcacgca cccacaagaa tagcgtctca cgccatgcgc agttttacgt
     7261 aagccagatg ctgggattta ttgccgataa ctacgatcag gcgctaacca ttaacgacgt
     7321 tgcggagcat gtcaaactca atgctaacta cgcgatggga atattccagc gggttatgca
     7381 attgacgatg aagcagtaca tcacggcgat gcgcatcaat cacgtacgtg ccttattgag
     7441 cgatactgac aaaacgatcc tcgatgtcgc tctgactgcc gggttccgat ccagcagccg
     7501 tttttacagt acttttagca aatttgtcgg tatgtcgccg caacaatacc gcaagctaag
     7561 ccagcaacga cgccagacga tgcccggcta aagccggata ccactatcag ccaaaaaaat
     7621 aattcacctg tcgataaacg gcgggtgaaa ttgctcgcta tcaataatta acccattgtt
     7681 tattaaacaa taatatcaat aactgaccat tattccatca ctttacaccc cctatttgac
     7741 ggggtaatac ttgcccacgt cacattcata cggcgggtcg gcaaggcgta aattgcacgg
     7801 cctccacaac cgggtaaaag atgatgaaag tattaattgt tgaaagtgag tttctgcatc
     7861 aggacacctg ggttggcaac gcggttgagc gtctggcgga tgccttgagc caacaaaatg
     7921 ttaccgtcat taaatcgaca tccttcgatg acggctatgc catcttgtcc gcgaacgaag
     7981 ccattgactg tctgatgttt agctaccaaa tggaacaacc ggatgagcac ctgagcgtca
     8041 ggcaattgat cggtaagctt cacgagcgtc agcaaaacgt gcccgttttc ctgttaggcg
     8101 acagggaaaa agcgacggca tcgctggacc gcgacctgct ggagcttgtc gatgaattcg
     8161 cctggattct ggaagacacc gctgacttta tcgccggacg cgccgttgcc gccatgaccc
     8221 ggtatcgcca gcaactgtta ccgccgctgt ttaacgcgtt gatgaaatac agcgacattc
     8281 atgaatattc atgggcggcg ccgggacatc agggcggcgt cggtttcact aaaacgcctg
     8341 ccggtcgctt ttatcacgat tattatggcg aaaacctgtt ccgcagcgat atggggattg
     8401 agcgtaccac gctcggttca ctcctcgacc ataccggcgc gtttggcgaa agcgagaaaa
     8461 acgccgcccg cgtattcggt gctgaccgct cctggtccgt ggttgtcggg acctcaggtt
     8521 ctaaccgtac tattatgcag gcctgtatga cggataatga tgtcgttgta ctggatcgta
     8581 actgccataa atccatcgaa caggggctga tcctcactgg ggccaaaccg gtatatatgg
     8641 tgccaagccg taaccgttac ggcattatcg ggccaatcta cccgcaggaa atgcagcctg
     8701 aaaccttgca gaaaaaaatc agcgccagcc cgctgaccaa aaccaaagcc ggacagaaac
     8761 cgtcttacag cgtggtgacc aactgtacct atgacggcgt atgctataac gccaaagagg
     8821 cgcaggatct gctggcaaaa accagcgatc gcattcactt cgacgaagca tggtacggct
     8881 atgcgcgctt caacccgatt tattgcgatc actacgcgat gcgcggcgag ccaggcgacc
     8941 ataacggtcc gaccgtgttt gccacccact ccacgcacaa attactgaac gcgctttcac
     9001 aagcttccta cattcacgtc cgtgaaggcc gtggcgcggt gaatttctcc cgcttcaacc
     9061 aggcctatat gatgcatgcc accacctctc cgttatatgc catctgcgca tccaacgatg
     9121 tggcggtatc gatgatggac ggtaacagcg gcctgtccct gactcaagag gtgattgacg
     9181 aagcggttga tttccgtcag gcgatggcgc gtctttataa agagtttacc gatgaaggcg
     9241 actggttctt taaaccgtgg aataaagacg tcgtcaccga tccacaaacc ggtaaaacgt
     9301 atgacttcgc cgacgcgccg gcaaaactgc tggcaaccga ccagaactgc tgggtcatgc
     9361 gccccgggga aacctggcac ggctttaaag acctgccgga taactggagt atgctggacc
     9421 cgattaaagt cagtatcctg gcgccgggta tgggcgacga tggcgaactg gaagcatccg
     9481 gcgtacctgc tgcgctggtc acagcatggc ttggccgcca cggtatcgtg ccgacccgca
     9541 ccaccgactt ccagattatg ttcctgttct ccatgggggt aactcgcggg aaatggggaa
     9601 cgctgatcaa cacgctgtgc tccttcaaac atcattacga cgcgaatacg ccgctggcgc
     9661 aggtgatgcc ggaactggtg caggattatc ctgacactta cgcgaacatg ggtattcatg
     9721 acctgggcga taaaatgttt gcctggctac gtgaaaataa cccgggcgcc cgtctcaatg
     9781 ccgcctattc caccctgccg gttgcggaga ttaccccgcg cgacgcctac aacgcgatcg
     9841 tgaacaacaa tattgaaatg gtggcgattg aaaatctacc gggtcgcatt gcggcgaact
     9901 ccgttattcc ttacccgcca ggcatcccga tgctgctctc cggtgaaaac tttggcgatg
     9961 aaaacagtcc gcaggtgggt tacttacgct cactgcaatc ctgggatcat cacttccctg
    10021 gctttgagca tgaaaccgaa ggcacggaaa ttattgatgg cgtatatcac gttatgtgcg
    10081 tgaaagccta atcacaaaga gtcttttttt gaggatggca tgtattccct gagtattgct
    10141 gcaaaacaat aatactgtca tacctttttg cgcgggcccc atcccgcgct ttttttatac
    10201 aaaaatgaca agtttccact cgcgtacaac tttttgtaca ccctaattca tcgtacaaat
    10261 attgtaatat tattcaggaa agctatttta atgcagttt
//
LOCUS       DAJVBX010000171        10195 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.171, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000171 DAJVBX010000000
VERSION     DAJVBX010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 10195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10195
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.171"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            230..1471
                     /gene="mdtM"
                     /locus_tag="OPV72_003542"
     CDS             230..1471
                     /gene="mdtM"
                     /locus_tag="OPV72_003542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdtM"
                     /protein_id="HCR9915743.1"
                     /translation="MQRIIQFFSQRATTLFFPMALILYDFAAYLTTDLIQPGIINVVR
                     DFNADVSLAPASVSLYLAGGMALQWLLGPLSDRIGRRPVLIAGALIFTLACAATLLTT
                     SMTQFLVARFVQGTSICFIATVGYVTVQEAFGQTKAIKLMAIITSIVLVAPVIGPLSG
                     AALMHFVHWKVLFGIIAVMGLLALCGLLLAMPETVQRGAVPFSAVSVLRDFRNVFRNP
                     IFLTGAATLSLSYIPMMSWVAVSPVILIDAGGMSTSQFAWAQVPVFGAVIVANMIVVR
                     LVKDPTRPRFIWRAVPIQLSGLATLLLGNLLLPHVWLWSVLGTSLYAFGIGMIFPTLF
                     RFTLFSNNLPKGTVSASLNMVILTVMAVSVEVGRWLWFHGGRLPFHLLAAVAGVIVVF
                     TLATLLQRVRQHEAAELAAEK"
     gene            1558..2829
                     /locus_tag="OPV72_003543"
     CDS             1558..2829
                     /locus_tag="OPV72_003543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF445 domain-containing protein"
                     /protein_id="HCR9915744.1"
                     /translation="MNKIAELKRAKRLALSLLLIAAATFVTTLFLPPSFWVLSVKAIA
                     EAAMVGALADWFAVVALFRRIPIPFISRHTAIIPRNKDRIGENLGQFVQEKFLDTQSL
                     IALIRRHEPALLIGNWFSQPDNASRVGQHLLQIMSGFLELTDDARIQRLLKRAVHKAI
                     DKVDLSGTSALMLESMTKNDRHQVLLDTLIAQLIALLQRDSSRTFIARQIIRWLETEH
                     PLKAKILPTEWLGEHSAELVSDAVNSLLDDISHDRAHQIRHAFDRATYKLIDKLKHDP
                     EMAARAENIKSYLKEDEAFNRYLGEIWADLRQWLKTDINAEDSKVKQRIAHAGQWFGE
                     TLIADDALRASLNGHLEQAAHRVAPEFAAFLTRHISDTVKGWDARDMSQQIELNIGKD
                     LQFIRVNGTLVGGAIGLVLYLLSQIPALLSI"
     gene            3049..4233
                     /locus_tag="OPV72_003544"
     CDS             3049..4233
                     /locus_tag="OPV72_003544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR9915745.1"
                     /translation="MVHAQSASPRHPIFTALFGMMVLTLGMGVGRFLYTPMLPVMLAE
                     KQLTFNQLSWIASANYAGYLAGSLLFSFGLFHLPSRLRPMLLASAVATGILILSMAIF
                     TQPAVVMLVRFLAGVASAGMMIFGSMIVLHHTRHPFVIAALFSGVGAGIALGNEYVIG
                     GLHYALSAHSLWLGAGALAGILLLIVAMLIPPRAHALPPAPLARIENQPMSWWQLALL
                     YGFAGFGYIIVATYLPLMAKSAGSPLLTAHLWSLVGLAIIPGCFGWLWAAKHWGVLPC
                     LTANLLIQSACVLLSLASDSLLLLILSSIGFGATFMGTTSLVMPLARQLSAPGNINLL
                     GLVTLTYGIGQILGPLAASLSGNGASAIINATLCGAAALFFAALISTAQQIKQKRFVI
                     RE"
     gene            5032..5703
                     /locus_tag="OPV72_003545"
     CDS             5032..5703
                     /locus_tag="OPV72_003545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiH family protein"
                     /protein_id="HCR9915746.1"
                     /translation="MAQQVDGAAMPLDTEKVGIKGYLAFFLTIIFFSGVFSGSEGWWR
                     VFDFTVLNGSFGHVTGTQTFRGAGGTGAKDGFLFALELAPSVILSLGIIAITDGLGGL
                     RAAQQLMTPILKPLLGIPGICSLALIANLQNTDAAAGMTKELAQEGEITERDKVIFAA
                     WQTSGSAIITNYFSSGVAVFAFLGTSVIIPLVVILLFKFIGANLLRIWINIEERRHPA
                     QGAQS"
     gene            5700..6161
                     /locus_tag="OPV72_003546"
     CDS             5700..6161
                     /locus_tag="OPV72_003546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HCR9915747.1"
                     /translation="MTTQVRKNVMDMFIDGARRGFTIATTNLLPNVVMAFVIIQALKI
                     TGLLDWVGHICQPVMALWGLPGEAATVLLASLMSMGGAVGVAASLATAGALSGHDVTV
                     LLPAIYLMGNPVQNVGRCLGTAEVNAKYYPHIIAVCAINALLSIWVMQLIV"
     gene            6174..7346
                     /locus_tag="OPV72_003547"
     CDS             6174..7346
                     /locus_tag="OPV72_003547"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HCR9915748.1"
                     /translation="MPDLSAAEFTLLQGAHLFAPEDRGICDVLLANGKIIAVGADIPG
                     DIVPDCAVINLSGRMLCPGFIDQHVHLIGGGGEAGPTTRTPEVSLSRLTEAGITTVVG
                     LLGTDSVSRHPASLLAKTRALNEEGITAWMLTGAYHVPSPTITGSVEKDVALIDRVIG
                     VKCAVSDHRSAAPGGNQLTSMAAESRVGGLLGGKPGVSVFHMGSSKKGLQPLYDILEN
                     SDVPIGKLLPTHVNRSESLFEQALAFALKGGVIDITTSIPDPVAPAEGIARAVKAGVP
                     LSRVTLSSDGNGSQPLFDAAGNLTGIGVAGFESLLETLQTLVNHYGFSLTDALRPLTT
                     SVAAFLSLDGKGEIRPGNDADLLVFSADLRIEQVYARGKRMVNEGKACVKGTFEPA"
     gene            7465..8373
                     /gene="hypT"
                     /locus_tag="OPV72_003548"
                     /gene_synonym="qseD"
     CDS             7465..8373
                     /gene="hypT"
                     /locus_tag="OPV72_003548"
                     /gene_synonym="qseD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypochlorite stress DNA-binding transcriptional
                     regulator HypT"
                     /protein_id="HCR9915749.1"
                     /translation="MDVTGAGLHNIETKWLYDFLTLEKCRNFSQAAIIRNVSQPAFSR
                     RIRALEHAVGVELFNRQVSPLQLSEQGKIFHSQVRHLLQQLESNLTELRGGSDYTLRK
                     IKIAAAHSLSLGLLPTIVKQMPTQFTYAVEAIDVDQAVDMLREGQSDFIFSYHDENLQ
                     QAPFDNIRLFESRLFPVCANNGRGEPRYTLEQPHFPLLNYSQNSYMGRLINRTLTRHA
                     ELSFSTFFVSSMSELLKQVAMDGCGIAWLPEYAIRQEITDGRLIVLDADELVIPIQAY
                     AYRMNTRMSQVAETFWRDLRGLQAAL"
     gene            complement(8379..9113)
                     /locus_tag="OPV72_003549"
     CDS             complement(8379..9113)
                     /locus_tag="OPV72_003549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate/glutamate racemase family protein"
                     /protein_id="HCR9915750.1"
                     /translation="MKHTIGILGGMGPAATADMLEKFVELRHVSCDQQHIPLIVSSIP
                     DIPDRTACLLSGGPSPYRYLERYLHMLEDAGAECIVIPCNTAHYWFDDLQNVAKARMI
                     SILDATLGDIPPSARHVGLLATNATLATGLYQKKALARGLTLIQPEDAGQALVMQAIY
                     TLKRGDKTAAQALLLPQIDSLIARGAQAIIMGCTEIPLIVAGHERAIACPMIDSTASL
                     VRAAIRWYESWPDTRASLTGEQRLTA"
     gene            complement(9352..9882)
                     /locus_tag="OPV72_003550"
     CDS             complement(9352..9882)
                     /locus_tag="OPV72_003550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463368.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system tube protein Hcp"
                     /protein_id="HCR9915751.1"
                     /translation="MAGKWNVLSLLAFRPCQPALPHDNHGGGMDAIYLKLDGIEGESQ
                     IKGFENQIKLIAYNHNPTKRESGEARGTYIGGLTLTKPVDLATLGLYEHYCNGKTVKE
                     GVLTLCRSDKGAMLPFIIYTLTNVRISRMSNHGDAEGSATETVDLVYSHIRWDIPALA
                     SKSKTRRPLHRQALWR"
BASE COUNT         2150 a         2782 c         2655 g         2608 t
ORIGIN      
        1 cgtaaatttc ccgaggtgtg atgtgctgat tgttatctgt aatcgccaca cgttctgacg
       61 agattcagaa cgcgtctctt cctgtctgtg ttttcaccgg cagcgttttt gattacatga
      121 aattcagtac atccgcagcc gctgtttcca tcgcctgcct gacgtcacga tgacggtatt
      181 gagtttcgct gtcccatcat ggggttctcc gacatggagc gcatttttta tgcaacggat
      241 tattcagttt ttctcccaac gcgccacaac gttatttttc ccgatggcgc tgattttgta
      301 cgattttgcc gcctatctga cgacggatct gattcagcct ggcatcatta acgtcgtgcg
      361 cgattttaat gctgacgtca gtcttgcgcc ggcctcggtc agtctctatc tggcgggagg
      421 aatggcgttg caatggcttc tggggccgct atccgacagg attggccgcc ggccagtgct
      481 gattgcaggc gcattaattt ttactctcgc ctgcgcggct acgctgttga cgacctcaat
      541 gacgcagttt ctggttgccc gttttgtgca gggcaccagc atttgcttta tcgcaacggt
      601 cggctacgtc acggtacagg aggctttcgg tcaaaccaaa gccattaagc tgatggcgat
      661 tattacctcc attgtgctgg tcgctccggt tatcggcccg ctctccggcg ccgcgctgat
      721 gcacttcgtt cactggaagg tactgttcgg tattattgcg gtgatgggac tgttggcgtt
      781 gtgcggcctg ctgctggcga tgccagaaac ggtgcaacgc ggcgcggtgc cgttcagcgc
      841 ggtgagcgta ctgcgcgatt ttcgtaatgt gtttcgcaac ccgatttttc tcaccggggc
      901 ggcgacgctg tcgttgagct acatcccgat gatgagctgg gtggcggtgt cgccggtgat
      961 cctgatcgat gccggcggga tgagtacttc gcaattcgcc tgggcgcagg tgccagtatt
     1021 cggcgcggtg atcgtggcca atatgatcgt tgtgcgcctg gtgaaagatc caacccgacc
     1081 gcgttttatc tggcgcgccg taccaatcca gttaagcggg ctggcgacat tgcttctcgg
     1141 taatcttctt ctgccgcacg tctggctttg gtctgtgctg ggcaccagcc tgtacgcgtt
     1201 cggcattgga atgattttcc cgacgctgtt tcgcttcacg cttttctcca acaacttgcc
     1261 aaaagggacg gtttcggcct cgctgaacat ggtgattctg acggtgatgg cggtgtcggt
     1321 cgaagttggc cgctggctgt ggtttcacgg cgggagactg ccgtttcacc tgctggcagc
     1381 ggtggccggg gtgattgtgg tcttcaccct ggcgacatta ttacagcgcg tgcgccagca
     1441 tgaggcggca gaactggccg ctgagaagta aacactctgc cggatagagg cttatccggc
     1501 acaggatcat ctgatatttt ttgcacgttc ctgccgtctg gctctatcct taaccctatg
     1561 aataaaatcg ccgaactcaa acgcgccaaa cgcctggcgc tctcactgtt gctgatagcc
     1621 gccgcgacgt ttgtgaccac gcttttcctg ccgcccagtt tttgggtgct gagcgtaaaa
     1681 gctattgccg aagcggcgat ggttggcgcg ctggcggact ggtttgccgt ggtggcgctg
     1741 tttcgccgca ttcccattcc gtttatttca cgacatacgg cgattattcc ccgtaacaaa
     1801 gaccgaatcg gcgaaaatct tgggcaattt gtacaggaga agttccttga tacgcagtcg
     1861 ctgatcgcgc taatccgccg ccatgaaccc gcgctgctta ttggaaactg gttcagccag
     1921 ccggacaacg ccagccgggt cgggcagcat ctgctgcaaa ttatgagcgg ctttctggaa
     1981 ctaaccgatg acgcccgtat tcagcggctg ctcaagcgag cggtacataa ggcgattgat
     2041 aaagtggatc tttccggcac cagcgccctg atgctggaaa gcatgaccaa aaacgatcgt
     2101 caccaggtgt tactcgatac gctgatcgcc cagcttatcg ccctgttaca acgtgacagc
     2161 tcccgaacat ttatcgccag acagatcata cgctggctgg aaaccgagca tccgttaaaa
     2221 gcgaagattc tgccgaccga atggctggga gaacacagcg ctgaactggt ctccgacgcg
     2281 gtgaattctc tgctggatga tatcagtcac gaccgcgcac atcagattcg tcatgccttc
     2341 gatcgtgcga cgtataagct gatcgataag cttaaacatg atccggaaat ggctgcccgg
     2401 gcagaaaata ttaaaagtta tctgaaggaa gatgaggcgt ttaaccgcta tctcggcgag
     2461 atctgggcgg atctgcgcca gtggttaaaa acagatatca acgccgaaga ctcaaaggtg
     2521 aagcagcgca tcgctcatgc cggacaatgg tttggcgaga cgctgatcgc cgacgacgca
     2581 ttacgcgcct cgcttaacgg tcatctggaa caggccgcgc accgcgtcgc gccggaattc
     2641 gccgccttcc tgacgcgcca catcagcgat accgtaaaag gctgggatgc gcgcgatatg
     2701 tcgcagcaga ttgagcttaa tatcggtaaa gatttgcagt ttatccgcgt gaacggcacg
     2761 ctggtcggcg gcgctattgg tctggtgtta tatttactgt cgcaaatacc ggcactgctc
     2821 agtatctaag aaggggaagg cgcaattctc attcagatta actgccaaac cccgcacgtg
     2881 ggaggcatta atttaatgcc atttcccacc gatgcccctc ttctcaatcc gttattcgcc
     2941 tgcgcttcac tttcttttct tgcaaatttg aaacattaat tttacttttt attatcattt
     3001 acaacgacaa tccggcattc ctgccttact ttagcaaaga gaaaaaccat ggttcatgct
     3061 cagagcgctt cacctcgcca tcccattttt acggcgcttt tcggtatgat ggtattgacg
     3121 ctggggatgg gagttggccg ctttctgtat acgcccatgc tgccggtaat gctggcggaa
     3181 aagcagctaa cgtttaacca actctcctgg attgccagcg ccaattatgc agggtacctg
     3241 gcgggaagct tactgttttc ctttggcctt tttcatctcc cctctcgtct acgccccatg
     3301 ctgctggctt cggcggtcgc caccggtatt cttattctgt ctatggcgat atttactcag
     3361 cccgcggtcg tcatgttggt gcgcttcctg gcaggcgtcg cgagtgcggg aatgatgatt
     3421 tttggatcaa tgattgtgtt gcatcatacc cgccatccgt ttgtgatcgc cgcgctcttt
     3481 tccggcgtcg gggccgggat tgcactgggc aacgaatatg tcattggcgg tttacattat
     3541 gcgctttcgg cccattcgct atggctgggg gccggagcgc tcgccggtat attgctatta
     3601 atcgtggcaa tgttgattcc cccccgcgct catgcgctgc cgcctgcgcc cttagcaaga
     3661 atcgaaaatc agcctatgtc ctggtggcaa ctggcgctgt tatacggttt cgccggattc
     3721 ggctacatca ttgtcgctac ctatttgccg ctgatggcga aaagcgcggg ctctccgcta
     3781 ctcacggcac acctttggtc gttggtcggc ctggcgatca ttcccggctg cttcggctgg
     3841 ctgtgggcgg caaaacattg gggcgtcctg ccatgtctga ccgcgaacct gttgatccag
     3901 agcgcctgcg tgctgctgtc tctcgccagc gactcgttgt tgctgttaat actgagcagt
     3961 attggttttg gcgccacgtt tatgggcaca acctcactgg tgatgccgct tgcccgccag
     4021 ctcagcgcgc cgggcaatat taatttgtta ggcctggtga cgctaacgta tggtattggg
     4081 caaattctcg gtccgctcgc cgccagtctg tcaggcaatg gcgcgtcggc aattatcaac
     4141 gccacgcttt gcggcgccgc ggcgctcttt tttgccgcgc tgatcagcac cgcgcagcag
     4201 ataaaacaaa aacggtttgt gatacgtgaa taagcggtag agtaaacccg cgctatccgc
     4261 accgggttgt atctttaatg ctattcgcgg cgcaatgcgg atctgttttt aatagcacat
     4321 cctcaacacg ttatttcaag gtaaagatgc cactaaaaac tatacttatt ctatggtttt
     4381 tagtgttatc aatctgtcta ttattttata tacccttcct acttcaagtg gcttatgtgt
     4441 tggctacgga ttacccggcc catccatggg cctcgccctg acgggccgtt gctcacccca
     4501 gtcacatcgt tattatgctc ctggggactc actcccttgc cgcctttacg caactcgaat
     4561 tattttggct atatattcca ttatgatgat tatcgctccc tctcaaatca tcacaattat
     4621 aaataaatca catcatgaaa ttaattcgat tattcgtttt ttattacctg cccgtaggat
     4681 tcttagggcg caagctgacc catcagcggc tactgacctg accgtgacaa ttcctcttaa
     4741 ggcgtgaaat tgactaacgt caaatttatt tccccttttt cctgctcccg gctctggcct
     4801 gcgtcaacac ctgtttcttt gcttttttac cgcgcgttat accgtccacg gttccccgcg
     4861 cctccggcag tagcgaggat ggtgattttt cgcgctgcta tgcaagaaac gcatagcacg
     4921 atacatactt gcattttgtc cttaccctta tggctgataa ggtctttctg tttcgggctt
     4981 tttggcctgt ggctacaacc aacacatcat caaaaaaatt cggggatcgc tatggcgcaa
     5041 caagtggacg gggcggccat gccgcttgat acagaaaagg tcgggataaa gggatacctg
     5101 gcgttttttc tcaccattat tttcttttcc ggcgtatttt ccggaagcga aggctggtgg
     5161 cgcgtttttg attttaccgt actcaacggg tcattcggtc atgtgaccgg tacgcagacc
     5221 tttcgcggcg cgggcggaac gggcgcgaaa gatggcttcc tttttgcgct ggagctggcg
     5281 ccgtcggtta tcctttctct gggtatcatc gcgattacgg atgggcttgg cggtctgcgg
     5341 gcggcacagc aattgatgac gcccatcctg aaaccattgc ttggcattcc cggcatttgc
     5401 tcactggcgc tgatcgccaa cctgcaaaat accgacgccg cggcgggtat gaccaaagag
     5461 ctggcgcagg aaggcgaaat caccgaacgc gataaagtga tttttgccgc ctggcagacc
     5521 agcggcagcg ctattatcac caactatttc tcctccggcg ttgcggtatt cgcctttctg
     5581 ggaacgtcag tcatcattcc gctggtggtc attctgctat tcaaatttat cggcgcaaac
     5641 cttttgcgca tctggattaa catcgaagaa cgccgtcacc ctgcgcaagg agcccaatca
     5701 tgacgactca ggtacgtaag aatgtcatgg atatgtttat cgatggcgca cgccgcggtt
     5761 ttaccatcgc cacgaccaac ctgttaccca atgtggtcat ggcatttgtc attattcagg
     5821 cgctgaaaat taccggtctg ctcgactggg taggccatat ctgccagccc gtgatggcgt
     5881 tgtgggggct tcccggcgaa gcggctacgg tgcttctggc ttcgctgatg agtatgggcg
     5941 gcgccgttgg cgtggcggcc agtctggcta ccgccggcgc gctaagcggc cacgatgtta
     6001 ccgtactact gccagccatt tacctgatgg gaaacccggt acagaatgtc ggccgctgtc
     6061 tcggtactgc cgaagtcaac gccaaatatt acccgcatat tatcgcagtc tgcgccatca
     6121 atgcgctgct gtcgatctgg gtcatgcagc ttattgttta ataaggagtt atcatgcctg
     6181 atttatccgc cgcggagttt accttgttac agggtgcgca cctgtttgcg ccagaagacc
     6241 ggggcatctg cgatgttctg ctcgcgaatg gcaaaattat tgccgtcggc gctgacatcc
     6301 ccggcgatat cgtaccggac tgtgcggtga ttaatcttag cggtcgtatg ctgtgcccgg
     6361 gctttatcga ccaacacgtt catctgatcg gcggcggcgg cgaagcgggg ccgacgacgc
     6421 ggacgccgga agtctctctg agccgcctga cggaagccgg gataacaacg gtcgtcggcc
     6481 tgcttggcac cgactccgtc agccgtcatc ccgcgtcgct gttagccaaa acgcgagcgc
     6541 taaatgagga ggggatcacc gcctggatgc tcacgggcgc ttatcacgtt ccgtcgccga
     6601 ccattactgg ctcggtagaa aaagacgtcg cgctgatcga tcgcgtcatt ggcgtgaaat
     6661 gcgcagtctc cgaccaccgt tccgccgcgc ccggcgggaa tcaactcacc agcatggcag
     6721 ccgaatcacg cgttggcggc ctgctgggcg gcaaacccgg tgtcagcgtt tttcatatgg
     6781 gcagcagcaa aaaagggtta cagccgctgt atgacatcct ggaaaacagc gacgtgccga
     6841 tcggtaaact gctgcctacc cacgtcaacc gtagcgaatc gcttttcgag caggcgctgg
     6901 cgtttgcgct taaaggcggc gtgatcgaca ttaccaccag tatcccggat cccgtcgcgc
     6961 cggcggaggg cattgccaga gcggtaaaag ccggcgtccc gctttcccgg gtgacgctca
     7021 gttcagacgg caacggcagc cagccgctat ttgacgctgc cggaaatctg acgggtatcg
     7081 gcgtcgcggg cttcgaaagt ttgctggaga cgttgcagac gctggttaac cactacggat
     7141 tcagcctgac cgatgctctg cgtccgctga caaccagcgt agccgccttc ctcagtctgg
     7201 acggcaaagg cgaaatccgt cccggtaacg atgcggatct gctcgtcttt agcgcagatt
     7261 tacgcattga gcaggtgtat gcgcgcggca aacgcatggt caatgagggg aaagcctgcg
     7321 taaaaggtac ctttgaaccg gcgtaattcc cgctagtttc agactgcccc atcacggcat
     7381 tctgaaagag gacgggataa gtggttgtca gccgcccgaa tggacgtaga atgccccttc
     7441 ggacggctga caggataacg gtaaatggat gtaactggag caggtttgca caatattgag
     7501 acaaaatggc tatatgattt tctgacgctg gaaaagtgcc gcaatttctc tcaggccgcc
     7561 attatccgca acgtatcgca acccgctttt agccggcgga ttcgcgccct ggaacatgcc
     7621 gtgggcgttg aactgtttaa ccgacaggtc tcgccgctac agctttccga acagggtaaa
     7681 atctttcact cccaggttcg ccacctgtta cagcagctgg aaagtaatct gaccgaactg
     7741 cgcggcggca gcgattatac gctgcgtaaa atcaagattg ccgccgccca ctcgctctcc
     7801 ctcggcctgt taccgaccat cgttaagcag atgccgacgc agtttaccta cgccgttgag
     7861 gcgatagatg tcgaccaggc ggtggatatg ttacgtgagg ggcaaagcga ttttatcttt
     7921 tcctatcacg atgaaaacct gcaacaagcg ccgtttgata atatccgcct gtttgagtcg
     7981 agactgtttc cggtttgcgc caacaatggc cggggcgagc cgcgctatac gcttgagcag
     8041 ccgcactttc ccctgcttaa ttacagtcaa aactcctata tgggccggct gataaatcgt
     8101 accctgactc gccatgctga actgagtttc agtacatttt tcgtctcttc gatgagtgaa
     8161 ttgttaaaac aggttgcgat ggacggctgc ggaatcgcct ggttacccga gtatgctatc
     8221 cgtcaggaga ttaccgacgg gcgcctgata gtgcttgatg ccgacgaact ggttatcccg
     8281 atccaggctt atgcttatcg catgaatacc cgcatgagtc aggtagccga aacattttgg
     8341 cgcgacctgc gtgggcttca ggccgcgctg taaacacatc aggcggtaag gcgttgttcc
     8401 ccggtcaaag aggcgcgggt gtctggccag gactcatacc aacgaatcgc cgcgcgcacc
     8461 agcgacgctg tggaatcaat catcgggcac gctatcgcgc gttcatgtcc ggccacaata
     8521 agcggaattt cggtacaccc cataataatt gcctgagcgc cacgggcaat aaggctatcg
     8581 atttgcggca gcagcagcgc ttgcgccgca gttttatcgc cacgtttaag cgtataaata
     8641 gcctgcatta ccaacgcctg ccccgcgtct tctggctgaa ttaacgtcag cccccgcgcc
     8701 agcgctttct tttgatataa cccggttgcc agcgtcgcat tggtcgccag cagaccaacg
     8761 tgccgcgccg atggcggaat atcccccagg gtggcgtcca ggatgctgat cattcgcgct
     8821 ttcgcgacgt tctgtaaatc atcaaaccaa taatgcgcag tgttgcatgg gataacgata
     8881 cactccgccc cggcgtcttc cagcatatgc agataacgct ccagataacg gtatggcgaa
     8941 ggcccgccgg ataacagaca tgctgtacga tcgggaatat cagggataga gctgacaatg
     9001 agcgggatgt gttgttgatc acaactgaca tgtcgcaatt caacaaattt ttccaacata
     9061 tccgccgttg ccgcaggtcc catccccccc agtatcccaa tggtgtgttt catcgctttt
     9121 cccgcttatt tacgtcaagg tcagaaacac actatcaact tgatgtgtat ataaaaaatg
     9181 ccgttttatt agcggctatg cgtaaaaatc ataacgggtg taagggccat gcgttatcgc
     9241 cttttcaggc aatcgattgg ttacatgagc gctcatcagc cttcgcaagc cgctaaatgc
     9301 catttcgcta tacagcatcg cccactgcga gtccgcaagc ttgttttgtc ctcatcgcca
     9361 cagcgcctgt cggtgaaggg gccgccgtgt tttgcttttc gacgccaatg cgggaatatc
     9421 ccagcgaata tggctataaa ccaaatccac ggtctccgtg gcgctgcctt cggcgtcgcc
     9481 atgattgctc atgcgtgaaa ttcgcacatt ggtgagcgta taaataataa atggcagcat
     9541 tgcgccctta tcactacggc ataatgtcag cacgccttct ttcaccgttt tcccgttaca
     9601 atagtgctca tagaggccaa gcgtagcaag atcgactggc tttgtcagcg tcaaccctcc
     9661 aatatatgtc cctctcgctt cgccggactc ccgtttcgtc gggttgtggt tgtaagcaat
     9721 aagttttatt tggttttcaa aacctttgat ctggctttcg ccttcaatac cgtccagttt
     9781 taaatagatg gcgtccatcc cccctccgtg attatcatgc ggcaaagcag gctgacaagg
     9841 acggaacgcc aacaatgaaa gaacgttcca ttttccagcc atttcgttgg tgtctctgta
     9901 taccagatta aataccgaca atctgctata actggattct tgctaaatac cttctgccat
     9961 caacaatcca ttttacaata gcgctactga cctgaaatct attacgcctg gcattcaagc
    10021 atcgtttcct gaataaccat agccgctata agaaccatat caaaaaagaa atatcaatat
    10081 catttcttat ttttatccga gaaattactt aattccacag aatcggaatg tagacaattc
    10141 ttattccttt tcacatcaat gggtttttta gacttttgtc atatcgaaaa caacc
//
LOCUS       DAJVBX010000172        10128 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.172, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000172 DAJVBX010000000
VERSION     DAJVBX010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 10128)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10128)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10128
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.172"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..780)
                     /gene="nadK"
                     /locus_tag="OPV72_003551"
     CDS             complement(<1..780)
                     /gene="nadK"
                     /locus_tag="OPV72_003551"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) kinase"
                     /protein_id="HCR9915752.1"
                     /translation="MNNHFKCIGIVGHPRHPTALTTHEMLYRWLCDQGYEVIVEQQIA
                     HELQLKNVPTGTLAEIGQQADLAVVVGGDGNMLGAARTLARYDINVIGINRGNLGFLT
                     DLDPDNALQQLSDVLEGRYISEKRFLLEAQVCQQDRQKRISTAINEVVLHPGKVAHMI
                     EFEVYIDETFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSA
                     RPLVINSSSTIRLRFSHRRSDLEISCDSQIALPIQEGEDVLI"
     gene            904..1494
                     /gene="grpE"
                     /locus_tag="OPV72_003552"
     CDS             904..1494
                     /gene="grpE"
                     /locus_tag="OPV72_003552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HCR9915753.1"
                     /translation="MSSKEQKTPEGQAPEEIIMDQHEEVEAVEPNDSAEQVDPRDEKI
                     ANLEVQLAEAQTRERDTVLRIKAEMENLRRRTEQDIEKAHKFALEKFVNELLPVIDSL
                     DRALEVADKANPDMAAMVEGIELTLKSMLDVVRKFGVEVIAETNVPLDPNVHQAIAMV
                     ESEEVPAGNVLGIMQKGYTLNGRTIRAAMVTVAKAK"
     gene            complement(1576..2133)
                     /locus_tag="OPV72_003553"
     CDS             complement(1576..2133)
                     /locus_tag="OPV72_003553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001688360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HCR9915754.1"
                     /translation="MSEDYVIEWDKNFADDLNVVANVFLSHNPTLWPTIFSQLSTQPE
                     IFEDEDEDEYGLQDVLDCSGGDLGNNELAQAFLQVLRGEGFIHLVDWKGEDEEGELAN
                     FAADRFYELTKNLTDSEELRNLLVEITQEDEISDVCEAGDRYLDEIFERIQTELNKRG
                     FQIFDLNEGSDTYNVVVLPMSEYKK"
     gene            complement(2254..3540)
                     /locus_tag="OPV72_003554"
     CDS             complement(2254..3540)
                     /locus_tag="OPV72_003554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026171.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HCR9915755.1"
                     /translation="MEHISTTTLIIILIIMVVISAYFSGSETGMMTLNRYRLRHMAKQ
                     GNRSAKRVEKLLRKPDRLISLVLIGNNLVNILASALGTIVGMRLYGDAGVAIATGVLT
                     FVVLVFAEVLPKTIAALYPEKVAYPSSFLLAPLQILMMPLVWLLNTITRLLMRLMGIK
                     TDIVVSGSLSKEELRTIVHESRSQISRRNQDMLLSVLDLEKVSVDDIMVPRNEIIGID
                     INDDWKSIERQLTHSPHGRIVLYRDSLDDAISMLRVREAWRLMAEKKEFTKEMMLRAA
                     DEIYYVPEGTPLSTQLIKFQRNKKKVGLVVNEYGDIQGLVTVEDILEEIVGDFTTSMS
                     PTLAEEVTPQNDGSVIIDGTANVREINKAFNWHLPEDDARTVNGVILEALEEIPVAGT
                     RVRIEQYDIDILDVQENMIKQVKVVPVKPLRESVAE"
     gene            complement(3560..4351)
                     /locus_tag="OPV72_003555"
     CDS             complement(3560..4351)
                     /locus_tag="OPV72_003555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane protein YpjD"
                     /protein_id="HCR9915756.1"
                     /translation="MPVFALLALVAYSFSLALIVPGLLQKNSGWRRMAILSAVIALVC
                     HAVALESRILPGGDSGQNLSLLNVGSLVSLMICTVMTIVASRNRGWLLLPIVYAFALI
                     NLAFATFMPNEYITHLEATPGMMVHIGLSLFSYATLIIAALYALQLAWIDYQLKNKKL
                     AFSNEMPPLMSIERKMFHITQIGVVLLTLTLCTGLFYMHNLFSTENIDKAVLSIVAWF
                     VYIVLLWGHYHEGWRGRRVVWFNVAGAGILTLAYFGSRILQQFVS"
     gene            4517..5878
                     /gene="ffh"
                     /locus_tag="OPV72_003556"
     CDS             4517..5878
                     /gene="ffh"
                     /locus_tag="OPV72_003556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HCR9915757.1"
                     /translation="MFDNLTDRLSRTLRNISGRGRLTEDNVKETLREVRMALLEADVA
                     LPVVREFINRVKEKAVGHEVNKSLTPGQEFVKIVRSELVAAMGEENQTLNLAAQPPAV
                     VLMAGLQGAGKTTSVGKLGKFLREKHKKKVLVVSADVYRPAAIKQLETLAEQVGVDFF
                     PSDVGQKPVDIVNAALKEAKLKFYDVLLVDTAGRLHVDEAMMDEIKQVHASIKPVETL
                     FVVDAMTGQDAANTAKAFNEALPLTGVVLTKVDGDARGGAALSIRHITGKPIKFLGVG
                     EKTDALEPFHPDRIASRILGMGDVLSLIEDIESKVDRAQAEKLATKLKKGDGFDLNDF
                     LEQLKQMKNMGGMASLMGKLPGMGQIPDNVKSQMDDKVLVRMEAIINSMTLKERAKPE
                     IIKGSRKRRIAQGCGMQVQDVNRLLKQFDDMQRMMKKMKKGGMAKMMRSMKGMMPPGF
                     PGR"
     gene            6222..6470
                     /gene="rpsP"
                     /locus_tag="OPV72_003557"
     CDS             6222..6470
                     /gene="rpsP"
                     /locus_tag="OPV72_003557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000256453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HCR9915758.1"
                     /translation="MVTIRLARHGAKKRPFYQVVVTDSRNARNGRFIERVGFFNPIAS
                     EKEEGTRLDLDRIAHWVGQGATISDRVAALIKEVKKAA"
     gene            6489..7037
                     /gene="rimM"
                     /locus_tag="OPV72_003558"
     CDS             6489..7037
                     /gene="rimM"
                     /locus_tag="OPV72_003558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HCR9915759.1"
                     /translation="MSKQLAAQVPAEPVVLGKMGSSYGIRGWLRVFSSTEDAESIFDY
                     QPWFIQKAGQWQQVQLESWKHHNQDLIIKLKGVDDRDAANLLTNCEIVVDSSQLPALE
                     EGDYYWKDLMGCQVVTAEGYDLGKVIDMMETGSNDVLVIKANLKDAFGIKERLVPFLD
                     GQVIKKVDLATRTIEVDWDPGF"
     gene            7082..7849
                     /gene="trmD"
                     /locus_tag="OPV72_003559"
     CDS             7082..7849
                     /gene="trmD"
                     /locus_tag="OPV72_003559"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HCR9915760.1"
                     /translation="MFIGIVSLFPEMFRAITDYGVTGRAVKKGLLNIQSWSPRDFAHD
                     RHRTVDDRPYGGGPGMLMMVQPLRDAIHAAKAAAGEGAKVIYLSPQGRKLDQAGVSEL
                     ATNQKLILVCGRYEGVDERVIQAEIDEEWSIGDYVLSGGELPAMTLIDSVARFIPGVL
                     GHEASAIEDSFADGLLDCPHYTRPEVLEGMEVPPVLLSGNHAEIRRWRLKQSLGRTWL
                     RRPELLENLALTEEQARLLAEFKTEHAQQQHKHDGMA"
     gene            7890..8237
                     /gene="rplS"
                     /locus_tag="OPV72_003560"
     CDS             7890..8237
                     /gene="rplS"
                     /locus_tag="OPV72_003560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012768745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HCR9915761.1"
                     /translation="MSNIIKQLEQEQMKQNVPSFRPGDTVEVKVWVVEGTKKRLQAFE
                     GVVIAIRNRGLHSAFTVRKISNGEGVERVFQTHSPVVDSIAVKRRGAVRKAKLYYLRE
                     RTGKAARIKERLN"
     gene            complement(8394..9614)
                     /gene="dgcN"
                     /locus_tag="OPV72_003561"
     CDS             complement(8394..9614)
                     /gene="dgcN"
                     /locus_tag="OPV72_003561"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DgcN"
                     /protein_id="HCR9915762.1"
                     /translation="MNKEFSLSRPTFKRTLRRISIISVLLTMTLIWLLICVASVLTLK
                     QYAQKNLDLTAATMAHSLEAALVFSDSAAAAETLATLGRQGQFSAAEVRDKNGRTIAS
                     WRYDARAADDKLIGLISHWLFPLPVSQPVWHNGRAIGEVRLVARDSLIGHFIWLSLAV
                     LTGCILLASGIALLLTRYLHNGVVDALQNITEIVHDVRTNRNFSRRVPDERIAEFHLF
                     AQDFNSLLDEMEEWQLRLQAKNAQLLRTALHDPLTGLANRAAFRSCINALMKDNSARS
                     SSALLFLDGDNFKYINDTWGHAAGDRVLIEVAKRLAEFGGSRYQTYRLGGDEFAMVLY
                     GVHSEYEVQRICAALSQAFNRPFELHNGQRITMTLSIGFALTWEHATAEKLQELADRN
                     MYQAKHRRAERSLN"
     gene            complement(9607..10125)
                     /locus_tag="OPV72_003562"
     CDS             complement(9607..10125)
                     /locus_tag="OPV72_003562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfiR family protein"
                     /protein_id="HCR9915763.1"
                     /translation="MRFSHRFILLLSLLLASLPLYAQCVTEEEKSVRAIVSGIVSYTH
                     WPALSGPPRLCIFSSARFVRVLSEEANWAFPYQPLVIRTTQEALSARCDGFYFGNESP
                     AYQVELTRHYPVNALLLIAEQNTECIIGSAFCLIINNDEVKFSVNLDSLSHSGVRVNP
                     EVLMLARNQKHE"
BASE COUNT         2587 a         2479 c         2687 g         2375 t
ORIGIN      
        1 aatcagcaca tcttctcctt cctgaatagg cagcgctatc tgactgtcgc agctaatttc
       61 cagatcgcta cggcgatgcg aaaaacgcag acgaatcgtg ctactgctgt taatgactaa
      121 cgggcgcgcc gacaaggtat gcgggaacat cggcaccagg gtgatggcat ccagtgaagg
      181 ggtcagaata gggccgcctg cggagagcga ataggcggtg gagccggtcg gcgtagaaat
      241 gatcagacca tcagatcgct gtgaaaaagc gaaggtttca tcaatataaa cctcgaattc
      301 gatcatatgc gccacttttc ccggatgcag caccacttca ttaatggctg tgctgatacg
      361 cttctggcgg tcctgttggc agacctgcgc ttccagcaga aaacgttttt cggagatata
      421 gcgtccttcc agcacatccg ataattgttg cagggcgttg tccggatcga gatcggtcag
      481 gaagccaaga ttaccgcggt taatgccaat cacattgatg tcataacgcg ccagcgtacg
      541 cgctgcgcca agcatattgc cgtcgccgcc cacaactacc gccagatccg cctgttgacc
      601 aatttccgcc agcgtgccgg ttggcacatt ttttagctgt aattcgtggg cgatttgttg
      661 ctccacaatg acctcataac cctgatcgca tagccaacgg tagagcattt catgtgtcgt
      721 gagtgcggtg ggatgacgcg gatgccccac aatgccgata cacttgaaat gattattcat
      781 ttttctgagg tccttgtagc gaagattgat gacaatgtga gtacttccct tgaaaccctg
      841 aatctgatcc ccataataag cgaagttagc gagatgaatg cgaaaaaaaa cgcggagaaa
      901 ttcatgagta gtaaagaaca gaaaacgcct gaggggcaag ccccggaaga aattatcatg
      961 gatcagcacg aagaggttga ggcagttgaa ccaaacgatt ctgctgagca ggtggatccg
     1021 cgcgatgaaa aaattgcgaa tctggaagtt cagcttgccg aagcccagac tcgcgaacgc
     1081 gacaccgtgt tgcgtatcaa agcggaaatg gaaaacctgc gccgccgtac tgaacaggat
     1141 atcgaaaaag cgcataaatt cgctctcgag aagttcgtca acgaattgct gccggtaatc
     1201 gatagcctgg atcgcgcgct ggaagtcgca gacaaagcca atccggatat ggcggcaatg
     1261 gtcgaaggga ttgagctgac gctgaagtct atgctggatg tggtgcgtaa gttcggcgtg
     1321 gaagtgattg ctgagaccaa cgtgccgctg gacccgaacg tgcatcaggc gattgcgatg
     1381 gtggaatcgg aagaggttcc ggcaggcaat gtgctgggta ttatgcagaa aggctacacg
     1441 ctgaacggtc gtaccattcg cgcggcgatg gtgactgtag cgaaggcgaa gtaaaagtct
     1501 aatggccgat gtaaagtcgg ccattttttt agcttaaaaa atcctgcact tccagccacg
     1561 gcgtgttgaa atcctctatt ttttatattc gctcattggc agaacgacca cattataggt
     1621 gtcagatcct tcattcagat caaaaatctg gaagcccctc ttattgagtt cggtctggat
     1681 gcgttcaaag atctcgtcaa ggtaacggtc cccggcttca cagacatcgg agatttcatc
     1741 ctcttgggtt atttcgacaa gaagatttct taattcctca gaatccgtca ggttttttgt
     1801 gagttcataa aagcgatctg cggcaaaatt agccagttcg ccttcttcat cttcaccttt
     1861 ccagtcaacg aggtgaataa atccttcgcc gcgtagaact tgtaaaaatg cctgtgccag
     1921 ctcgttattt ccgagatcgc caccgctaca atccaggacg tcttgcaacc catattcgtc
     1981 ttcatcttcg tcttcaaaga tttcaggttg cgtcgaaagt tgagagaaaa tagtgggcca
     2041 taaggttggg ttgtgcgata aaaaaacgtt ggcgacgacg ttgaggtcgt ctgcaaaatt
     2101 cttatcccat tcaattacat aatcttctga cataacatca atatcctttc tgaatgcctg
     2161 aaaagacatt attgcattgt taagtaaatg gcaggaattg atggaatctt aaaagacggc
     2221 gataaaaaag gcgaaccgga gttcgccatt gtgttactcc gccacactct cgcgcagcgg
     2281 ttttaccggt acaaccttta cctgcttaat catattttcc tgtacatcga gaatatcgat
     2341 atcgtactgc tcaatgcgca cgcgcgtgcc agcaaccgga atttcctcca gcgcctccag
     2401 aatcaccccg ttgacggtgc gcgcgtcatc ttccggcagg tgccagttaa acgctttatt
     2461 gatttcccgg acgttggcgg taccgtcaat aatgaccgaa ccgtcgtttt gcggcgtgac
     2521 ctcttccgcc agtgtcggcg acatcgatgt ggtgaagtcg ccaacgatct cctcgagaat
     2581 atcttccacg gtgaccagcc cctggatatc gccatattcg ttgacgacca gtccgacttt
     2641 ctttttattg cgctgaaatt taatcagttg cgtactgagc ggcgtacctt ccgggacgta
     2701 atagatttca tcggcggcgc gcagcatcat ctctttggtg aactcttttt tctcggccat
     2761 taaccgccag gcttcacgca cgcgcagcat actgatggcg tcatccagcg aatcgcgata
     2821 gagcacaatg cgtccgtgcg gcgagtgggt gagctgccgc tcgatagact tccagtcgtc
     2881 attgatatcg atcccgataa tttcattacg cggcaccatg atgtcatcca cgctgacctt
     2941 ttccagatcg agaaccgaca gcagcatatc ctgattgcgg cgagagattt gcgaacggga
     3001 ttcatgcacg atagtgcgta attcctcttt gcttaacgac ccgctgacca cgatgtccgt
     3061 tttaattccc atcagacgca tcagcaggcg ggtgatggtg ttaagtaacc acaccagcgg
     3121 catcatcagt atctgtaacg gcgccagcag gaagctgctg ggataggcca ctttttccgg
     3181 atagagcgcg gcgatagttt tgggcaggac ttcggcaaaa actaacacga caaacgtcag
     3241 taccccggtg gcgatagcca cgccggcatc gccgtaaagc cgcataccca caatcgtgcc
     3301 gagcgccgag gcaagaatgt tgaccaggtt attgccaatc agcaccaggc ttatcagtcg
     3361 gtcgggttta cgcagtaatt tttctacccg ttttgccgag cgattacctt gcttcgccat
     3421 atggcgtaaa cggtaacggt ttagcgtcat cattccagtt tcggaaccgg aaaaataggc
     3481 cgagatgacc accatgatga ttaatatgat aatcagcgtg gtggtggaga tgtgttccag
     3541 gggaaactcc tttaaaagct tagcttacaa attgctgtaa tatgcggcta ccaaaatagg
     3601 ccagcgtcag aatacccgcg cctgcgacgt taaaccacac gacccgacga ccccgccagc
     3661 cttcatggta atgcccccac agcagaacga tatagacaaa ccatgccacg atagagagca
     3721 cggctttatc aatattttca gtactgaaca ggttatgcat gtaaaacagg ccggtacaca
     3781 gagtaagggt cagcagtacg acgccaatct gcgtgatatg aaacattttg cgctcaatgc
     3841 tcatcaatgg cggcatttca ttactaaacg ccagcttttt gttcttcaac tgatagtcga
     3901 tccacgccag ttgtagcgca tacagcgcgg cgattatcag cgtcgcgtaa gagaaaagcg
     3961 acagaccgat gtgcaccatc atgcctgggg tcgcttccag atgcgtaata tattcattag
     4021 gcatgaacgt ggcgaaggcc aggttaatca gcgcaaaagc atagacaatg ggcagaagta
     4081 gccagccgcg attacgcgac gcgacaatgg tcatcaccgt gcagatcatc aggctgacca
     4141 gcgaaccgac attcagcagg ctcaggtttt gtccactgtc gccgccgggc agaatacgcg
     4201 attccagcgc gacagcatgg cacaccagcg cgatgaccgc agaaagaata gccatacgcc
     4261 gccagccgct gtttttttgc aacagtccgg gaacgatcag cgcgaggctg aaggagtagg
     4321 cgacaagggc aagtaaagca aaaacgggca tagttgtgtc gacagttgac cagtgagaaa
     4381 gagaagcagt atagcgttac gtgaccgcag ctccaaccgt tgcataacaa caaagacggc
     4441 ttcatggtat actgtggcga aattctgtaa ctgtgtcgct gcggcgacca accgtttcca
     4501 ccccaggcga gagacaatgt ttgataattt aaccgatcgt ttgtcgcgca cgctgcgcaa
     4561 tatcagtggc cgtgggcgcc ttactgaaga caacgttaaa gagacgctgc gcgaagtgcg
     4621 catggcgctg ctggaggctg acgttgcgct gccggtagtg cgtgagttca tcaatcgcgt
     4681 aaaagagaaa gcggttggtc atgaagttaa caaaagcctg accccagggc aggagttcgt
     4741 caagattgtc cgtagcgaac tggttgcggc aatgggcgaa gaaaaccaga ccctgaatct
     4801 ggctgcgcag ccgccagccg tagtattgat ggcgggtctg cagggggcgg gtaaaaccac
     4861 cagcgtcggt aagttgggta aattcttgcg cgagaagcac aagaagaaag tgctggtcgt
     4921 ctctgccgac gtctatcgcc cggcggcgat caaacagctc gaaacgctgg ctgagcaggt
     4981 tggcgtggat ttcttcccgt ctgatgtcgg ccagaaaccg gttgatatcg tcaacgccgc
     5041 gctgaaagaa gcgaagctca aattctacga cgtgctgctg gtggataccg ccggtcgtct
     5101 gcacgttgac gaagcgatga tggacgaaat caaacaggtc cacgcttcta tcaagccagt
     5161 agaaacgctg tttgtcgtcg atgcgatgac cggtcaggat gcggcgaata ccgcaaaagc
     5221 ctttaacgaa gcgctgccgt taaccggtgt ggtgctgacc aaagttgatg gtgatgcgcg
     5281 tggcggtgcg gcgctctcta ttcgtcatat caccggcaag ccgattaaat tcctcggtgt
     5341 cggcgagaaa accgacgcgc tggagccgtt ccacccggat cgtatcgcct cgcgtattct
     5401 cggcatgggc gacgtactgt ctcttatcga agatatcgaa agcaaagttg accgcgcaca
     5461 ggctgagaag ctggcgacca aactgaagaa aggcgacggt ttcgacctga acgacttcct
     5521 ggagcagctc aaacagatga aaaacatggg cggtatggcc agtctgatgg gcaaattacc
     5581 gggcatgggg cagattccgg acaacgttaa atcgcagatg gatgataagg tgctggtgcg
     5641 tatggaggcg atcatcaatt cgatgacgct gaaagaacgc gcgaagccgg aaatcattaa
     5701 aggttcccgc aagcgtcgta tcgcgcaggg ctgtgggatg caggtgcagg acgttaaccg
     5761 ccttctgaaa cagttcgacg acatgcagcg catgatgaag aaaatgaaga agggcgggat
     5821 ggcgaagatg atgcggagta tgaaggggat gatgccgcct ggttttccag gccgctaatt
     5881 tcccggctag gctcacttgc tatttcggca ccggggtgtg ctagccatcc tcacgtactg
     5941 cgtggccgct aaaacaaggg tataaggcta tcttgtttgc cattttagcc ccggggtgtg
     6001 ctcgaaatgc tcacgtactg cgtgtacgct ccgctttctg cgcgcacgcc ggagctaaac
     6061 tggctgcacc gatatacgcc ttttatccct tgtttcgtgt tcagtagcaa gatgctgatt
     6121 gcattttccc cagaaatcag taaaattttc gggcttttaa tatgacgccg ggctccgttc
     6181 ctcgatgagg cccggttgtt ttattcacac aagaggatgt tatggtaact attcgtttag
     6241 ctcgtcacgg cgctaaaaag cgtccgttct accaggttgt tgtcaccgac agccgtaatg
     6301 cacgcaacgg tcgcttcatt gagcgcgttg gtttcttcaa cccaatcgct agcgaaaaag
     6361 aagaaggcac ccgcctggat ctggatcgca tcgctcactg ggttggccag ggcgcaacca
     6421 tttccgatcg cgttgcggcg ctgatcaaag aagtaaaaaa agcagcttaa tctgtcacgg
     6481 tggtcatgat gagcaagcaa ctcgccgcac aagtacccgc tgaaccggtt gtactgggga
     6541 aaatgggttc ttcatacggt atccgtggtt ggctcagagt gttttcctcc actgaagacg
     6601 ccgaaagcat ttttgactat cagccctggt ttatccagaa ggcgggtcag tggcagcagg
     6661 tacagctgga aagctggaag caccacaatc aggatctgat catcaagctg aaaggcgttg
     6721 acgatcgaga tgccgcgaat cttctgacca attgcgaaat tgtcgtggat tcctcgcaac
     6781 ttcctgcgct tgaggaggga gactactact ggaaagacct gatgggttgc caggtagtca
     6841 ccgctgaagg ctacgatctc ggtaaagtta tcgacatgat ggaaaccggg tcgaatgacg
     6901 ttctcgtcat taaggcgaac ctgaaagatg catttggtat caaggaacga ctagtaccgt
     6961 tcctcgatgg gcaggttatc aagaaagtcg atctcgctac tcgtactatc gaagtagact
     7021 gggatcctgg tttttaaacc accggataaa cggtaataaa tggcgttatg gggattggct
     7081 tgtgtttatt ggcatcgtta gcctgtttcc tgaaatgttc cgcgcaatta ccgattacgg
     7141 ggtaactggc cgggcagtaa aaaaaggcct gctgaacatc caaagctgga gtcctcgcga
     7201 cttcgcgcat gaccggcacc gtaccgtgga cgaccgtcct tacggcggcg gaccggggat
     7261 gttaatgatg gtgcaaccct tgcgggacgc cattcatgca gcaaaagccg cggcaggtga
     7321 aggcgctaaa gtgatttatc tgtcgcctca gggacgcaag cttgatcaag cgggcgttag
     7381 cgagctggcc acgaatcaga aactcattct ggtgtgtggt cgctacgaag gcgtagatga
     7441 gcgcgtaatt caggccgaaa ttgacgaaga atggtcaatt ggcgattacg ttctcagcgg
     7501 tggcgaacta ccggcaatga cgctgattga ctccgtcgcc cggtttatac cgggggttct
     7561 ggggcatgag gcatcagcaa tcgaagattc gtttgctgat gggttgctgg attgtccgca
     7621 ctatacgcgc cctgaagtgt tagaggggat ggaagtaccg ccagtattgc tgtcgggaaa
     7681 ccatgctgag atacgtcgct ggcgtttgaa acagtcactg ggccgaacct ggcttagaag
     7741 acctgaactt ctggaaaacc tggctctgac tgaagagcaa gcaaggttgc tggcggagtt
     7801 caaaacagaa cacgcacaac agcagcataa acatgatggg atggcatagg cccccgaata
     7861 tcagtttacc caggataaga gattaaatta tgagcaacat tattaagcaa cttgaacaag
     7921 agcagatgaa gcagaacgta ccttccttcc gtccgggcga taccgtggaa gtgaaagtat
     7981 gggttgttga aggtaccaag aaacgtctgc aggcattcga gggcgtggtt atcgctattc
     8041 gtaaccgcgg tctgcactct gcattcactg ttcgtaaaat ttccaacggc gaaggcgttg
     8101 agcgtgtctt ccagactcac tctccggtag ttgacagcat tgctgttaaa cgtcgtggtg
     8161 ctgttcgtaa agctaaactg tactacctgc gtgagcgtac tggtaaagca gctcgtatca
     8221 aagagcgtct taactaagaa cgcgctttcg caacatccga aagcttgtag aaaagaaggg
     8281 gctggcatta cgctggcccc tttttttatg ggttgctcca cgccatagac ggttgcatga
     8341 ttaagctggg tctgtggtat caacgctgag tcagaaacgg cctggcccgt tccttagttt
     8401 agcgagcgtt ctgcacgccg gtgtttagcc tgatacatat ttcgatcggc cagttcttgt
     8461 agtttttcgg cagtggcatg ttcccatgtc agcgcaaagc caatactcag ggtcatcgtt
     8521 attcgctggc cgttatgcag ttcaaaaggt cgattaaacg cctgggatag tgctgcgcaa
     8581 atacgttgta cttcatactc cgaatgtaca ccgtaaagca ccatcgcaaa ttcatcgccg
     8641 ccgagtcggt aagtctgata acggctacca ccgaattccg ctaatctttt ggcaacctct
     8701 ataagtacgc ggtcgcctgc cgcatgtccc caggtatcat taatatattt aaagttatcg
     8761 ccatccagaa ataacaatgc cgaactgcta cgagcggaat tgtccttcat cagcgcgtta
     8821 atacagctgc gaaatgccgc gcgattggca agccccgtca gcggatcgtg caacgcggta
     8881 cgtagtaatt gtgcattttt agcctgaagc cgtagctgcc attcttccat ctcatccaga
     8941 aggctattga aatcctgcgc aaacaggtga aattccgcaa tacgctcatc aggtacccgg
     9001 cgtgaaaaat ttcggttagt gcgaacgtcg tgtacaattt cagtaatatt ttgtagcgca
     9061 tccacaacgc cattgtgtaa ataacgcgtg agtagcaggg caatgccgga tgctagcaga
     9121 atacatcctg tcagcactgc cagcgatagc cagataaaat gaccaataag gctgtcgcgg
     9181 gcgacaagcc gtacttcgcc gatagccctg ccgttgtgcc agacgggttg cgataccggc
     9241 aatggaaaaa gccagtggct aattaagccg atgagcttat cgtctgcggc tcgcgcatca
     9301 tatcgccatg aggcgatagt acggccattt ttatcgcgga cctccgccgc tgaaaattgt
     9361 ccctggcgtc ccagtgtggc gagcgtttcc gctgcggccg cgctatcgga aaataccagt
     9421 gccgcttcaa ggctatgggc cattgtggcg gcggtcaaat cgagattctt ttgcgcatac
     9481 tgtttgagcg taaggacaga cgcaacgcaa attaatagcc agatcaatgt cattgtaagc
     9541 agcacgctga ttatactaat ccgccgtagt gtgcgtttaa atgttggtct ggacagagaa
     9601 aattccttat tcatgctttt gattccgtgc aagcattaat acttctggat tcactctcac
     9661 gccgctatgc gagagggagt ccaggttgac ggaaaatttg acttcatcat tgttaatgat
     9721 cagacaaaat gcgctgccaa taatacattc ggtattttgc tcggcaatta ataacaaggc
     9781 attaactgga taatgacgcg ttaactccac ctgataagct ggcgattcat tgccaaagta
     9841 aaaaccatca cagcgggcgc tcagggcttc ttgtgtggta cggatgacaa gcggttgata
     9901 agggaaagcc cagttagcct cttcgctaag taccctgaca aaacgcgcag atgaaaatat
     9961 gcatagcctt ggcggcccgg ataacgctgg ccagtgtgta taactgacga taccggagac
    10021 aatggcgcgt acggatttct cttcttccgt gacacattga gcatacagag gcaagcttgc
    10081 taataatagc gataacagaa ggataaatcg gtgagaaaaa cgcattaa
//
LOCUS       DAJVBX010000173        10071 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.173, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000173 DAJVBX010000000
VERSION     DAJVBX010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 10071)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10071)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10071
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.173"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..927)
                     /gene="sapB"
                     /locus_tag="OPV72_003563"
     CDS             complement(<1..927)
                     /gene="sapB"
                     /locus_tag="OPV72_003563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter permease SapB"
                     /protein_id="HCR9915764.1"
                     /translation="MIIFTLRRLLLLLVTLFFLTFIGFSLSYFTPHAPLQGASLWNAW
                     VFWFNGLLHWDFGVSSINGQLISEQLKEVFPATMELCILAFGFALMVGIPVGMLAGVT
                     RSKWPDRFISALALLGFSIPVFWLALLLTLFFSLTLGWLPVSGRFDLLYEVKPVTGFA
                     IIDAWISDSPWRDEMVMSAIRHMVLPVLTLSVAPTTEVIRLMRISTIEVYDQNYVKAA
                     ATRGLSRFTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLIHAI
                     RQQDYAAISAGVMVIGSLVIVVNVISDILGAMA"
     gene            complement(924..2573)
                     /gene="sapA"
                     /locus_tag="OPV72_003564"
     CDS             complement(924..2573)
                     /gene="sapA"
                     /locus_tag="OPV72_003564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein SapA"
                     /protein_id="HCR9915765.1"
                     /translation="MRLVLSSLIVIAGLLSSQATAATAPEQTASADIRDSGFVYCVSG
                     QVNTFNPQKASSGLIVDTLAAQLYDRLLDVDPYTYRLVPELAESWEVLDNGATYHFHL
                     RRDVSFQKTAWFTPTRKLNADDVVFTFQRIFDRRHPWHNINGSSFPYFDSLQFADNVK
                     SVRKLDNNTVEFRLTQPDASFLWHLATHYASVMSAEYAAQLSRKDRQELLDRQPVGTG
                     PFQLSEYRAGQFIRLQRHDGFWRGKPLMPQVVVDLGSGGIGRLSKLLTGECDVLAWPA
                     ASQLTILRDDPRLRLTLRPGMNIAYLAFNTDKPPLNNPAVRHALALSINNQRLMQSIY
                     YGTAETAASILPRASWAYDNDAKITEYNPQKSREQLKALGIENLTLHLWVPTSSQAWN
                     PSPLKTAELIQADMAQVGVKVVIVPVEGRFQEARLMDMNHDLTLSGWATDSNDPDSFF
                     RPLLSCAAINSQTNFAHWCNPEFDSVLRKALSSQQLASRIEAYDEAQNILEKELPILP
                     LASSLRLQAYRYDIKGLVLSPFGNASFAGVSREKHEEVKKP"
     gene            complement(2685..3665)
                     /gene="pspF"
                     /locus_tag="OPV72_003565"
     CDS             complement(2685..3665)
                     /gene="pspF"
                     /locus_tag="OPV72_003565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage shock protein operon transcriptional
                     activator"
                     /protein_id="HCR9915766.1"
                     /translation="MAEFKDNLLGEANCFLEVLEQVSRLAPLDKPVLIIGERGTGKEL
                     IANRLHYLSSRWQGPLISLNCAALNENLLDSELFGHEAGAFTGAQKRHPGRFERADGG
                     TLFLDELATAPMLVQEKLLRVIEYGELERVGGSQPLQVNVRLVCATNADLPAMVKEGT
                     FRADLLDRLAFDVVQLPPLRERQSDIMLMAEHFAIQMCRELRLPLFPGFTDRAKETLL
                     HYAWPGNVRELKNVVERSVYRHGSSEHPLDEIVIDPFQRYPAEPPAPALPAASATPDL
                     PLNLREFQLQQEKALLQRSLQQAKFNQKRAADLLALTYHQFRALLKKHQL"
     gene            3836..4504
                     /gene="pspA"
                     /locus_tag="OPV72_003566"
     CDS             3836..4504
                     /gene="pspA"
                     /locus_tag="OPV72_003566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage shock protein PspA"
                     /protein_id="HCR9915767.1"
                     /translation="MGIFSRFADIVNANINALLEKAEDPQKLVRLMIQEMEDTLVEVR
                     SNSARALAEKKQLSRRIEQATAQQTEWQEKAELALRKDKDDLARAALIEKQKLTDLIA
                     TLEQEVTLVDDTLARMKKEIGELENKLSETRARQQALMLRHQAASSSRDVRRQLDSGK
                     LDEAMARFESFERRIDQMEAEAESHRFGKQQSLDQQFANLKADDEISEQLAQLKAKMK
                     QDNQ"
     gene            4564..4788
                     /gene="pspB"
                     /locus_tag="OPV72_003567"
     CDS             4564..4788
                     /gene="pspB"
                     /locus_tag="OPV72_003567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response membrane protein PspB"
                     /protein_id="HCR9915768.1"
                     /translation="MSALFLAIPLTIFVLFVLPIWLWLHYSNRAGRGELSQSEQQRLL
                     QLTDDAQRMRERIQALEDILDAEHPNWRER"
     gene            4788..5147
                     /gene="pspC"
                     /locus_tag="OPV72_003568"
     CDS             4788..5147
                     /gene="pspC"
                     /locus_tag="OPV72_003568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response membrane protein PspC"
                     /protein_id="HCR9915769.1"
                     /translation="MSGINLNKKLWRMPQKGMVRGVCAGIADYLDVPVKLVRILVVLS
                     IFFGLAFFTVVAYIVLSFVLDPMPDNLAAGKPQPTSGELLDTVDRELAAGEKRLREME
                     RYVTSDTFTLRSRFRQL"
     gene            5170..5388
                     /gene="pspD"
                     /locus_tag="OPV72_003569"
     CDS             5170..5388
                     /gene="pspD"
                     /locus_tag="OPV72_003569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage shock protein PspD"
                     /protein_id="HCR9915770.1"
                     /translation="MNTRWQRAGQKVKPGFKIAGKLVLLTALRYGPAGVAGWAVKSVA
                     RRPLKMLLAFALEPVLRKAANKISQRYK"
     gene            5464..5778
                     /gene="pspE"
                     /locus_tag="OPV72_003570"
     CDS             5464..5778
                     /gene="pspE"
                     /locus_tag="OPV72_003570"
                     /EC_number="2.8.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase PspE"
                     /protein_id="HCR9915771.1"
                     /translation="MLKKGIFALALFVAMPLYAAEYWIDVRIPEQYQREHIQGAINIP
                     LKEIKSHIETVVPDRNDTVKLYCNSGRQSGMAKQMLLDMGYTHAMNMGGISRLDMPKV
                     KK"
     gene            5927..7324
                     /locus_tag="OPV72_003571"
     CDS             5927..7324
                     /locus_tag="OPV72_003571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcjX family protein"
                     /protein_id="HCR9915772.1"
                     /translation="MKRLKTELNALVNRGVDRHLRLAVTGLSRSGKTAFITAMVNQLL
                     NVHAGARLPLLSAVREERLLGVKRVPQRDFGIPRFTYDEGILQLYGNPPAWPTPTRGV
                     SEIRLALRYRSNDSLLRHFKDTSTLYLEIVDYPGEWLLDLPMLAQDYLSWSRQMNGLL
                     QGQRAEWAAKWRQLCDGLDPLAPADENRLAEIAAAWTDYLHQCKSQGLHFIQPGRFVL
                     PGDMAGAPALQFFPWPDVDAFGESKLAQADKQTNAGMLRERFNYYCEKVVKGFYKNHF
                     LRFDRQIVLVDCLQPLNSGPQAFNDMRLALTQLMQSFHYGQRTLFRRLFSPVIDKLLF
                     AATKADHVTLDQHANMVALLQQLIQDAWQNAAFEGISMDCLGLASVQATTSGVIEVNG
                     EKIPALRGNRLSDGAPLTVYPGEVPSRLPGQAFWDKQGFQFEAFRPQVMDVDKPLPHI
                     RLDAALEFLIGDKLR"
     gene            7321..8382
                     /locus_tag="OPV72_003572"
     CDS             7321..8382
                     /locus_tag="OPV72_003572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01620 family protein"
                     /protein_id="HCR9915773.1"
                     /translation="MSEPLKPRIDFAEPLKEEPTSAFKAQQTFSEAESHTFAPAAIDE
                     RPEDEGVAEAAVDAALRPKRSLWRKMVMGGLALFGASVVGQGVQWTMNAWQTQDWVAL
                     GGCAAGALIVGAGVGSVVTEWWRLWRLRQRAHERDEARELLHSHSVVKGRAFCEKLAQ
                     QAGIDQSHPALQRWYAAIHETQNDREIVGLYAHLVQPVLDAQARREISRFAAESTLMI
                     AVSPLALVDMAFIAWRNLRLINRIATLYGIELGYYSRLRLFRLVLLNIAFAGASELVR
                     EVGMDWMSQDLAARLSTRAAQGIGAGLLTARLGIKAMELCRPLPWADNDKPRLGDFRR
                     QLIGQLKETLQKSKSSPEK"
     gene            8530..10071
                     /gene="tyrR"
                     /locus_tag="OPV72_003573"
     CDS             8530..10071
                     /gene="tyrR"
                     /locus_tag="OPV72_003573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator TyrR"
                     /protein_id="HCR9915774.1"
                     /translation="MRLEVFCEDRLGLTRELLDLLVLRSIDLRGIEIDPIGRIYLNFA
                     ELEFTDFSSLMAEIRRISGVTDVRTVPWMPSEREHLALSALLEALPEPVLSLDMKSKV
                     EMANPASCQLFAQSQERMRHHTAAQLINGFNFQRWLDGNPQSSHNEHVVINGQNFLME
                     ITPVHLQNENDEYVLTGAVVMLRSTIRMGQQLQNLSTQDLSAFSQIIAVSAKMKHVVE
                     QARKLAMLSAPLLITGDTGTGKDLFAYACHQASPRSAKPYLALNCASIPEDAVESELF
                     GHAPEGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGEDHEIHVDVR
                     VICATQKNLVELVQKGLFREDLYYRLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQ
                     GVPRPKLSADLSTVLTRYGWPGNVRQLKNAIYRALTQLEGYELRPQDILLPDYDAATV
                     AVGEDAMEGSLDDITSRFERSVLTQLYRSYPSTRKLAKRLGVSHTAIANKLREYGLSQ
                     KKGEE"
BASE COUNT         2422 a         2505 c         2826 g         2318 t
ORIGIN      
        1 agccatagca cccaaaatat cggaaatcac attgaccaca ataaccagcg acccaatgac
       61 catcacgcca gcggaaatag cggcatagtc ctgctgacga atggcgtgaa ttaaccatcg
      121 tcccagccct ggccagctga aaaccatttc ggtaatcatc gccagcgtta acatggttga
      181 aaactgcaga ccaagacggg gaatgaccgg cggcagcgca ttatgcaaca cgtgacggcg
      241 taaaatcgta aagcgcgaca agccgcgcgt ggccgccgct ttaacgtagt tctgatcgta
      301 gacctcaata gtgctgattc gcatcaggcg gatcacctct gtggtcggcg cgacggaaag
      361 cgtgagcacc ggtaaaacca tatgtcgtat ggcgctcatt accatttcat cacgccacgg
      421 cgaatctgaa atccaggcgt caatgatggc gaaaccggta accggtttaa cttcataaag
      481 caggtcaaat cgcccggata ccggcagcca ccccagtgtg agcgaaaaga acagtgtgag
      541 cagaagcgcc agccagaaaa ccggaattga gaaacctaat agcgccagcg cgctgataaa
      601 acgatccggc catttgctac gcgtcacgcc agccagcatc ccgaccggga tgccgaccat
      661 cagcgcaaaa ccaaaggcga gaatgcacag ctccatcgtg gcgggaaaca cctctttaag
      721 ctgttcggag atcagctggc cgttaatgct ggacacgcca aagtcccagt gcagcagacc
      781 gttgaaccag aaaacccagg cattccataa tgatgcgcct tgtagcggcg cgtgcggcgt
      841 aaaatagctc aggctaaagc cgataaaggt caggaagaat agcgtcacca gcaacagcaa
      901 taaccgacgc agggtgaaga taatcatggt tttttcacct cttcgtgttt ttcgcgggag
      961 acgccggcaa aagacgcatt gccgaacggg cttaacacca gtcctttaat atcgtagcgg
     1021 taagcctgta agcgtagtga tgatgccagc ggcagtatcg gcagctcttt ctccaggata
     1081 ttctgcgctt cgtcatacgc ttctatgcgc gaagccaact gctgcgacga cagtgcctta
     1141 cgcagcacgc tgtcaaattc agggttacac cagtgggcga aattggtttg cgaattgatg
     1201 gccgcacagc ttaacagcgg tctgaaaaag ctatccggat cgttgctgtc cgtggcccag
     1261 ccggataagg tcagatcgtg attcatatcc atcaggcgcg cctcctgaaa acgaccttca
     1321 accggcacaa tgaccacttt tacgccaact tgcgccatat ccgcctgaat aagctccgcc
     1381 gtttttagcg ggcttgggtt ccaggcctga gaactggtcg gcacccagag atgcagcgta
     1441 agattctcaa tgcccagcgc ttttagttgt tcgcgcgatt tttgcggatt gtactccgta
     1501 attttggcat cgttatcgta agcccatgag gctctcggta aaatggaggc tgcggtttcc
     1561 gccgtgccgt aataaatcga ctgcatcagg cgctggttgt tgatcgataa ggccagcgca
     1621 tggcgcactg cgggattatt caacggcggc ttgtcggtgt taaaggccag ataggcgata
     1681 ttcatccccg ggcgcaacgt cagacgcaaa cgcggatcgt cgcgtaaaat agttagctgg
     1741 ctggcggcgg gccaggccag aacatcgcat tcaccggtca gtaatttcga taaacgccca
     1801 atacccccgg agcctaaatc caccaccact tgcggcatta gcggtttgcc gcgccaaaac
     1861 ccatcgtggc gctggagacg aataaactgc ccggcacggt actccgaaag ctggaaaggc
     1921 ccggtgccga ccggttgccg atcaagcagt tcctgacgat cttttcggct aagctgcgcg
     1981 gcgtactcag cagacatgac ggaagcgtag tgcgtggcca gatgccataa aaaggaggcg
     2041 tctggctgcg tcaggcgaaa ctcaacggtg ttattgtcca gcttacgcac gctttttaca
     2101 ttgtcggcga actgtaggct atcaaagtag gggaagctac tgccgttgat gttatgccac
     2161 ggatgtcgac gatcgaaaat ccgctgaaag gtaaagacga catcatcagc attgagtttt
     2221 cgggtcggcg taaaccaggc ggttttttga aaggaaacgt cgcggcgcag gtgaaaatgg
     2281 tacgttgccc cgttatccag cacttcccag ctttctgcca gctctgggac taaacgataa
     2341 gtatagggat cgacatccaa caggcggtca tataactggg cggccagggt atcgacgatg
     2401 aggccgctac tcgctttttg cggattaaag gtgttgacct gcccgctgac acaatacaca
     2461 aagccgctat cgcgaatatc tgcactcgca gtttgttcgg gcgcagtcgc agccgtagcc
     2521 tgactactca gtagacccgc tatcacgatc agagatgata aaaccaggcg cataatagtt
     2581 aagtttttga agttcaattt gcaaagtgta tcgcacttcg gcccgccacg taaaaatgtc
     2641 ggtggataac tggcgtaaat gtcgtcaatt agccggagaa atagctaaag ctgatgcttt
     2701 ttaagcaagg cgcgaaactg gtggtaggtg agcgccagca aatcggcggc tcgtttctgg
     2761 ttaaatttcg cctgctgtaa gctacgttgc agcagcgctt tttcctgttg cagttgaaac
     2821 tcccgcaagt tgagcggcag gtcaggcgtg gcggatgccg ctggcagggc gggcgcgggc
     2881 ggttcggcgg gatagcgttg aaaaggatcg ataacaattt catccaaagg atgttcgctg
     2941 ctgccgtggc gatacactga acgttcgact acgtttttca gctcgcggac attacccggc
     3001 caggcgtaat gcaacaacgt ttcttttgcc cgatcggtaa aaccaggaaa taagggcaga
     3061 cgtagctcac gacacatctg aatagcaaaa tgctcggcca tcagcatgat atcgctctgg
     3121 cgttcgcgca gcggcggcag ttgtacaacg tcaaaagcca gcctgtcgag cagatcggca
     3181 cgaaatgtcc cttccttcac catggcgggt aaatcggcat tagtggcgca tactaatcgc
     3241 acattaacct gtaacggttg gctgccgccg acgcgctcta gctcgccata ttcaatcacc
     3301 cgcagtagct tttcctgtac cagcattggc gctgtcgcca gttcatccaa aaacagcgtg
     3361 ccgccatcgg cgcgttcaaa acgaccggga tggcgttttt gcgccccggt aaaagcgccc
     3421 gcttcatggc caaacagttc ggagtccagc agattttcgt taagcgccgc gcagttaagc
     3481 gagataagcg gcccctgcca gcgtgaagag agatagtgca ggcgattggc gataagttct
     3541 ttacccgtac cgcgttcgcc aataatcagc actggcttat ccagcggcgc gagccgggag
     3601 acttgttcca gtacttcaag aaaacagttt gcctcgccga gcaggttatc tttaaattca
     3661 gccatgatga aaatcgccac ttgttagtgt ttttcaccac tttatccttt ttggctggcg
     3721 aggtaaaacg aaataattcc ttaactatca ataatataaa aagttggcac gcaaattgta
     3781 ttaatcatgt agcagggcat cgcccgttat cagaacatta tgtgaggatt gaattatggg
     3841 tattttttct cgttttgccg acatcgtgaa cgccaatatc aatgcgttgt tggaaaaagc
     3901 ggaagatccg cagaagctgg tgcgcctgat gattcaggag atggaagata cgctagtgga
     3961 ggttcgctcg aactccgcgc gagctttagc ggaaaagaaa cagttatccc gtcgtattga
     4021 acaggctacg gctcagcaga ccgagtggca ggaaaaagcg gaactggctc tgcgcaaaga
     4081 taaagacgat ctggcgcgcg ccgcattgat tgaaaaacaa aagctgaccg atttaattgc
     4141 tacgcttgaa caggaagtca cgctggtgga tgacacgctg gcgcgcatga agaaagagat
     4201 tggcgagctg gaaaacaaac tcagcgaaac acgcgctcgc cagcaggcgc tgatgctgcg
     4261 tcatcaggcg gcaagttctt cccgcgatgt ccgtcgtcag cttgacagcg gcaaactgga
     4321 tgaagccatg gcgcggtttg aatcctttga acgtcgtatc gatcaaatgg aagcggaagc
     4381 ggaaagccat cgttttggta agcagcaatc gctggaccaa cagtttgcca acctgaaagc
     4441 cgatgatgaa atcagcgagc agctggcgca gttgaaagcc aaaatgaagc aagataatca
     4501 ataatgacaa tggcggcgcc ggtacgcgcc gtcgctcatc agctttaggt gtaaggagaa
     4561 cgcatgagcg cgctatttct ggccatcccg ttaaccattt ttgtgttgtt tgtgttaccg
     4621 atttggctgt ggctgcatta cagcaaccgc gccggtcggg gagaactgtc gcaaagcgag
     4681 cagcaacgct tactgcaact cacagacgac gcgcaacgta tgcgcgagcg cattcaggcg
     4741 ctggaagata ttcttgatgc agagcatccg aactggagag agcgctaatg agtggaatca
     4801 atctgaataa aaaactatgg cgtatgccgc aaaagggcat ggtgcgtggc gtttgcgccg
     4861 ggatcgccga ctaccttgat gtaccggtaa aactggtgcg tattctggtc gtgctgtcga
     4921 ttttctttgg gctggcgttt tttaccgtag tggcctatat cgtcctgtct tttgtactgg
     4981 accctatgcc ggataatctg gccgcaggga aaccgcagcc gaccagcggc gaactgctgg
     5041 ataccgtaga cagagagctt gccgcaggcg aaaagcgttt gcgagaaatg gaacgctacg
     5101 tcacgtcaga tacgttcaca ctgcgtagtc gtttccgtca actgtaactg atatatcggg
     5161 aaggtgaaga tgaatactcg ctggcaacgc gccgggcaga aggtgaagcc cggcttcaaa
     5221 atagcaggta agctggttct gttgaccgcg ttacgctacg ggcctgccgg cgtggcggga
     5281 tgggcggtaa aatccgtcgc ccgtcgtccg ctaaaaatgt tgctggcgtt tgcgctggag
     5341 ccagtacttc gtaaggcggc gaataaaatt tcgcagcgtt acaaatagcg agtctggtca
     5401 taatatttcg ttaagctctg gcgtatagtg tgtgcgaaat acattacgtg tcaggacggg
     5461 agtatgttga aaaaaggaat atttgcgtta gcgttattcg tagccatgcc gctttatgcc
     5521 gcagaatact ggatagatgt ccgcattccg gaacaatatc aacgagagca tattcagggc
     5581 gcgattaata tcccattgaa ggagattaaa tctcatatcg aaacggtagt tccagacagg
     5641 aacgatacgg taaagttata ttgcaactcc gggcgacagt cgggcatggc aaaacaaatg
     5701 ttgcttgata tggggtatac gcacgcgatg aatatgggcg gcatcagtcg tcttgatatg
     5761 ccgaaagtaa aaaaatagat aatctattgc tcaatactca tactaaccgc ggcgcttaat
     5821 gcgccgttgt tgatctctcc gggtagttga taataacgtt tttgcacata tctataacgc
     5881 aggctcgtta ttattttttc ttctcttcag gctcaacagg atgtcaatga agcgacttaa
     5941 aactgaactc aacgcgctgg tcaatcgtgg ggtagacagg catttgcgtc ttgccgtaac
     6001 cgggttgagc cgcagcggta aaacagcgtt tatcacggcg atggttaacc agttgcttaa
     6061 tgtccacgcg ggcgcgcgct taccgttgct cagcgcggta cgcgaagaac gcctgcttgg
     6121 cgtaaagcgc gtgcctcaac gtgattttgg tattccccgt tttacctacg acgaggggat
     6181 acttcagctt tatggcaatc ctcccgcctg gcccacaccg acgcgcggcg tcagtgagat
     6241 tcggctggcg ttgcgctatc gctcaaacga ctcgctgctg cgccatttta aagatacctc
     6301 gacattgtat ctggagattg tggactatcc aggggaatgg ttactcgatc tgcccatgct
     6361 ggctcaggat tatttaagct ggtcccgtca gatgaacggc ttgttacaag ggcaacgcgc
     6421 tgagtgggcc gcaaaatggc ggcaactttg cgacgggctc gatccgctgg cgcccgccga
     6481 tgaaaatcgg ctggcggaga ttgccgccgc ctggacggat tatttgcatc agtgtaaatc
     6541 gcagggattg cattttattc agcctggacg gtttgttttg ccgggcgata tggcgggcgc
     6601 gccagcgttg cagtttttcc cgtggccgga tgtggacgcc ttcggcgagt caaaactggc
     6661 gcaggcggat aaacagacca acgctggaat gttgcgcgaa cgctttaact actattgcga
     6721 aaaggtggtc aaagggttct acaaaaatca ttttctacgc tttgatcgcc agattgtgct
     6781 ggtcgactgt ctgcaaccgc ttaatagcgg gccgcaggcg tttaatgata tgcgtctcgc
     6841 tttaacgcag ctgatgcaaa gttttcacta tggtcagcga actctgtttc gccgcttgtt
     6901 ttcgccggtg attgataaat tgctgttcgc cgcgacgaaa gccgaccatg tcaccctcga
     6961 ccaacatgcc aatatggtgg ccttgctcca gcagcttatt caggatgcct ggcaaaatgc
     7021 cgcgtttgaa ggcattagta tggattgcct ggggctggcg tcggtacagg cgaccaccag
     7081 cggcgtgatt gaggtcaacg gtgaaaaaat cccggcttta cgtggaaacc gtttgagtga
     7141 cggcgcgccg ttaaccgtgt accccggcga agtgccttcg cgtttgccgg gacaagcgtt
     7201 ttgggataag cagggctttc agttcgaagc ctttcgtccg caggtaatgg atgttgataa
     7261 accattacca cacattcgtc tggacgctgc gctggagttt ttaataggag ataagctgcg
     7321 atgagcgaac cgttaaaacc gcgtattgat tttgcagaac cgctaaagga ggaacctaca
     7381 tcggccttca aagcgcagca aactttcagc gaagcggagt cgcatacatt tgcgcctgcg
     7441 gctatcgatg agcgcccgga agacgaaggc gtggcagaag cggcggtcga tgccgcgctg
     7501 cgccccaaac gcagcctgtg gcgtaaaatg gtgatgggag ggctggcgct gtttggcgcg
     7561 agcgtggtcg ggcaaggcgt acagtggaca atgaatgcct ggcaaactca ggactgggtc
     7621 gctttaggcg gctgtgccgc aggcgcgctg atcgttggcg ctggcgtggg atcggtggtc
     7681 acggagtggt ggcgattatg gcgcttgcgc cagcgggcgc atgagcgcga tgaggcgcgt
     7741 gaactgttac atagccatag cgtcgtgaaa ggtcgcgcat tttgcgaaaa actggcgcag
     7801 caggcgggga ttgatcaatc acatccggca ttacaacgtt ggtatgccgc tattcacgaa
     7861 acgcaaaacg acagggaaat cgtcggcttg tatgcgcatc tggtacagcc ggtacttgac
     7921 gcgcaggcgc gacgtgagat tagccgtttc gccgcggaat cgactctgat gatcgctgtc
     7981 agtccgttag cgttggtgga tatggcgttt attgcctggc gtaatttacg cctgattaac
     8041 cgcatcgcaa cgctgtatgg cattgaactt ggttattaca gccgccttcg tctgttccgt
     8101 ctggtgttgc tgaatatcgc gtttgcgggg gccagtgagc tggtgcgtga agtcggtatg
     8161 gactggatgt ctcaggatct ggccgcacgc ctgtctacgc gcgcggcgca ggggattggc
     8221 gcaggcctcc ttaccgctcg actgggaata aaagcgatgg agctatgtcg accattgccg
     8281 tgggccgata acgataaacc acgtctcggt gattttcgtc gtcagcttat cggtcagcta
     8341 aaagagacgc tgcaaaagag taagtcgtcg cctgagaaat gaccttccac agggcgctga
     8401 ttgcctggct ttacgccgca gcgcccgttt ttccgccatg ctgtcaatat ttgttgacag
     8461 aatccttcct gccagccgaa tagtggctta tcatctattt aatggttcat tattcaggtg
     8521 aaggttccca tgcgtctgga agtcttttgt gaagaccgac ttggtctgac ccgcgaatta
     8581 cttgatttac tggtgttacg tagcattgat ttacgcggaa tcgagattga tcccattggg
     8641 cgaatttatc ttaattttgc tgagctggaa ttcaccgact tcagcagcct gatggccgaa
     8701 atccgccgta tttccggcgt aacggatgtc cgtaccgttc cctggatgcc gtccgaacgt
     8761 gaacatctgg ccctgagcgc gctgcttgag gcgttgccgg agccggtgct ctcattggat
     8821 atgaagagta aagtggagat ggcgaacccg gcgagttgtc aactttttgc ccagagccag
     8881 gagcgaatgc ggcaccatac cgccgcacaa ttaatcaacg gcttcaattt tcagcgctgg
     8941 ctggacggta acccgcaaag ctcccataac gaacatgtcg tgatcaacgg gcaaaacttc
     9001 ctgatggaga ttacgccggt acatttacaa aacgaaaatg acgaatacgt gttgaccggg
     9061 gcggtcgtga tgttgcgttc cacgattcgt atgggacagc agctacagaa tttgtccacg
     9121 caggatctga gcgcgtttag tcagattatt gccgtgagcg caaagatgaa gcacgtcgtt
     9181 gagcaggcgc gcaaactggc gatgctcagc gcgccgctgc tgattaccgg cgatacggga
     9241 accggcaaag atcttttcgc ctatgcctgt catcaggcaa gccctcgttc agcgaaaccg
     9301 tatctggcgc tcaactgcgc ttcaatcccg gaagatgcgg tagaaagcga actatttggc
     9361 catgcgccgg aaggtaaaaa aggctttttt gaacaggcga atggcggctc ggtgctgctg
     9421 gatgaaattg gcgaaatgtc accgcgtatg caggcgaagc tgctgcgttt tctcaatgat
     9481 ggtacgttcc gtcgtgtcgg cgaagatcac gaaattcatg ttgatgtccg cgttatctgc
     9541 gccacgcaga aaaatctggt ggagctggtg caaaaaggac tgttccgcga agatctctat
     9601 tatcgactta acgttctgac gcttaatttg ccgccgttgc gcgattgtcc gcaggatatt
     9661 atgccgttga ccgaactgtt cgtggcgcgt tttgccgacg aacagggcgt tccacgaccg
     9721 aaactgtctg ccgatctgag tacggtcctc actcgttacg gctggccggg taacgttcgc
     9781 cagcttaaaa atgcgattta tcgggcgctg acgcaactgg aagggtatga gctgcgtccg
     9841 caggacatcc tgttgcctga ctacgatgcc gcgacggtgg cagtcggcga ggatgcgatg
     9901 gaaggttcgc tggatgacat taccagtcgt ttcgaacgtt ctgtccttac tcagctttat
     9961 cgtagctatc cgagtacgcg taaactggcg aaacggttgg gggtatcgca taccgcgatt
    10021 gccaataagc tgcgtgaata tggtctgagc cagaagaagg gtgaagagta g
//
LOCUS       DAJVBX010000174        10040 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.174, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000174 DAJVBX010000000
VERSION     DAJVBX010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 10040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10040
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.174"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            94..747
                     /locus_tag="OPV72_003574"
     CDS             94..747
                     /locus_tag="OPV72_003574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000469196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCR9915775.1"
                     /translation="MFHYGKCVVRTLFLLLVCCSLSGCLSFGLILATDKDGNRHQSTW
                     KSDTVTALSLGKDSNGKTGWVFVGEHFDYLLTQGGDNVVALLKDATIRRDKMRVKDGV
                     KFLIDTDKKEFTGEVNVTYAWVDEKDKLAAVGYGFICADGAVNCTLSVMDLKGTIHQK
                     NKEQSVTQQLSFYHPFTVEFYQYQRSMSGAKFGRVLLPVTLALDIVTMPLQLLIFSR"
     gene            910..2952
                     /gene="prlC"
                     /locus_tag="OPV72_003575"
     CDS             910..2952
                     /gene="prlC"
                     /locus_tag="OPV72_003575"
                     /EC_number="3.4.24.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020317218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptidase A"
                     /protein_id="HCR9915776.1"
                     /translation="MTNPLLTSFSLPPFSAIKPEHVVPAVTKALADCRAAVEGVVAHG
                     APYSWENLCQPLAEADDVLGRIFSPISHLNSVKNSPELREAYEQTLPLLSEYSTWVGQ
                     HEGLYNAYRDLRDGDHYATLNTAQKKAVDNALRDFELSGIGLPKEKQQRYGEIATRLS
                     ELGNQYSNNVLDATMGWTKLITDEAELAGMPESALAAAKALAEAKEQEGYLLTLDIPS
                     YLPVMTYCDNQALREEMYRAYSTRASDQGPNAGKWDNSPVMEEILALRHELAQLLGFE
                     NYAHESLATKMAENPQQVLDFLTDLAKRARPQGEKELAQLRAFAKAEFGVEELQPWDI
                     AYYSEKQKQHLYSISDEQLRPYFPENKAVNGLFEVVKRIYGITAKERTDVDVWHPEVR
                     FFELYDENNELRGSFYLDLYAREHKRGGAWMDDCVGQMRKADGTLQKPVAYLTCNFNR
                     PVNGKPALFTHDEVITLFHEFGHGLHHMLTRIETAGVSGISGVPWDAVELPSQFMENW
                     CWEPEALAFISGHYETGEPLPKELLDKMLAAKNYQAALFILRQLEFGLFDFRLHAEFN
                     PQQGAKILDTLFEIKKQVAVVPSPTWGRFPHAFSHIFAGGYAAGYYSYLWADVLAADA
                     YSRFEEEGIFNRETGQSFLDNILTRGGSEEPMELFKRFRGREPQLDAMLEHYGIKG"
     gene            2959..3717
                     /gene="rsmJ"
                     /locus_tag="OPV72_003576"
     CDS             2959..3717
                     /gene="rsmJ"
                     /locus_tag="OPV72_003576"
                     /EC_number="2.1.1.242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(1516)-N(2))-methyltransferase
                     RsmJ"
                     /protein_id="HCR9915777.1"
                     /translation="MQICLMDETGATDGALSVLAARWGLEHDEDNPMALVLTPQHLEL
                     RKRDEPKLGGIFVDFVGGAMAHRRKFGGGRGEAVAKAVGIKGDYLPDVVDATAGLGRD
                     AFVLASVGCRVRMLERNPVVAALLDDGLTRGYADADIGGWLQERLQLIHASSLTALTD
                     ITPRPQVVYLDPMFPHRQKSALVKKEMRVFQSLVGPDLDADGLLEPARQLATKRVVVK
                     RPDYAPPLADVATPNAIVTKEHRFDIYAGTPLTE"
     gene            complement(3809..5278)
                     /gene="dtpB"
                     /locus_tag="OPV72_003577"
     CDS             complement(3809..5278)
                     /gene="dtpB"
                     /locus_tag="OPV72_003577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide/tripeptide permease DtpB"
                     /protein_id="HCR9915778.1"
                     /translation="MNTTAPTGLLQQPRPFFMIFFVELWERFSYYGVQGILAVFFVKQ
                     LGFSQEQAFITFGAFAALVYGLISIGGYVGDHLLGTKRTLVLGAIVLAIGYFMTGMSL
                     LNPDLIFIALGTIAVGNGLFKANPASLLSKCYQPKDPRLDGAFTLFYMSINIGSLLSL
                     SLAPVIADKFGYAVTYNLCGAGLIVALLVYFACRGMVKNIGSEPDHKPLRFRNLLLVL
                     LGTVVMIFLCAWLMHNVKIANLVLIVLSIVVTIFFFREAFRLDKTGRNKMFVAFILMI
                     EAVLFYILYAQMPTSLNFFAINNVHHEILGFAINPVSFQALNPFWVVVASPVLAAIYT
                     RLGSKGKDLTMPMKFTLGMFLCALGFLTAAAGMWFADAQGLTSPWFIVLVYLFQSLGE
                     LLISALGLAMVAALVPQHLMGFILGMWFLTQAAAFLLGGYVATFTAVPENITDPLQTL
                     PIYTGVFSKIGLVTLAVTVVMAIMVPWLNRMINTQGTEQ"
     gene            complement(5603..6037)
                     /gene="uspA"
                     /locus_tag="OPV72_003578"
     CDS             complement(5603..6037)
                     /gene="uspA"
                     /locus_tag="OPV72_003578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspA"
                     /protein_id="HCR9915779.1"
                     /translation="MAYKHILIAVDLSPESKVLVEKAVSMARPYNAKISLIHVDVNYS
                     DLYTGLIDVNLGDMQKRISKETHHALTELSTNAGYPITETLSGSGDLGQVLVDAIKKY
                     DMDLVVCGHHQDFWSKLMSSARQLINTVHVDMLIVPLRDEEE"
     gene            6425..6760
                     /gene="uspB"
                     /locus_tag="OPV72_003579"
     CDS             6425..6760
                     /gene="uspB"
                     /locus_tag="OPV72_003579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspB"
                     /protein_id="HCR9915780.1"
                     /translation="MISTVSLFWALCVVCIVNMARYFSSLRALLVVLRGCDPLLYQYV
                     DGGGFFTTHGQPNKQVRLVWYIYAQRYRDHHDEEFIRRCERVRRQFLLTSALCGLVVV
                     SLIALMIWH"
     gene            complement(6900..8396)
                     /gene="pitA"
                     /locus_tag="OPV72_003580"
     CDS             complement(6900..8396)
                     /gene="pitA"
                     /locus_tag="OPV72_003580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic phosphate transporter PitA"
                     /protein_id="HCR9915781.1"
                     /translation="MLHLFAGLDLHTGLLLLLALAFVLFYEAINGFHDTANAVATVIY
                     TRAMRSQLAVVMAAVFNFFGVLLGGLSVAYAIVHMLPTDLLLNMGSAHGLAMVFSMLL
                     AAIIWNLGTWYFGLPASSSHTLIGAIIGIGLTNAMMTGTSVVDALNIPKVINIFGSLI
                     ISPIVGLVFAGGLIFLLRRYWSGTKKRARIHLTPAEREKKDGKKKPPFWTRIALILSA
                     IGVAFSHGANDGQKGIGLVMLVLIGVAPAGFVVNMNASSYEITRTRDAINNVETYFEQ
                     RPDLLKAVTGVDQLIPSPEPGATEPTEFHCHPANTINALNRAKGMLANVESYDKLSVE
                     QRSQLRRIMLCISDTTDKVVKLPGVSSDDQRLLKKLKTDMLSTIEYAPVWIIMAVALA
                     LGIGTMIGWRRVATTIGEKIGKKGMTYAQGMSAQMTAAVSIGLASYTGMPVSTTHVLS
                     SSVAGTMVVDGGGLQRKTVTSILMAWVFTLPAAIILSGVLYWLSLKII"
     gene            8627..9829
                     /locus_tag="OPV72_003581"
     CDS             8627..9829
                     /locus_tag="OPV72_003581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000439232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCR9915782.1"
                     /translation="MERFDAVIIGAGAAGMFCAAQAGQAGSRVLLIDNGKKPGRKILM
                     SGGGRCNFTNLYVEPAAYLSQNPHFCKSALARYTQWDFIDLVGRYGIAWHEKTLGQLF
                     CDDSAQRIVDMLVAECDKGGVTMRLRSEVLSVERDESGFVLALNGETVTTQKLVIASG
                     GLSMPGLGASPFGYKIAEQFGLKVLPTRAGLVPFTLHKPLLEQLQTLSGVSVPCVITA
                     RNGTVFRENLLFTHRGLSGPAVLQISSYWQPGELVSINLLPDLSLEDVLNEQRNAHPN
                     QSLKNTLAMHLPKRLVECLQQLGLIPDVSLRQLNVRDQQTLVDTLTAWQVQPNGTEGY
                     RTAEVTLGGVDTNELSSRTMEARRVPGLYFIGEVMDVTGWLGGYNFQWAWSSAWACAQ
                     DLIALKIN"
BASE COUNT         2429 a         2534 c         2769 g         2308 t
ORIGIN      
        1 tgaaatcgtt tttattatga tgatagtgct ggttttacct tgtttatttg attaaaacga
       61 tagcgctaat aatagaaaag aaaggattca ttgatgttcc attatggaaa atgtgtcgtt
      121 cgcacgttgt ttttattact ggtttgctgt tcgctgtcgg gctgtctttc atttgggctg
      181 atacttgcca ccgataaaga tggcaatcgt catcagtcta cctggaaatc ggataccgtt
      241 accgcgcttt ccttaggtaa agatagcaac gggaaaacgg gctgggtgtt tgttggcgaa
      301 cattttgact acctgttgac ccagggcggc gataatgtgg tggcgctgtt aaaagatgcg
      361 actattcgcc gggataaaat gcgagtaaag gatggtgtta aattcctgat tgatacagat
      421 aagaaggagt ttacgggtga agtcaatgtg acttacgcct gggtggacga gaaagataaa
      481 ctggcggcgg taggctacgg gtttatttgt gcagacggcg cggtaaattg cacgctatcc
      541 gtcatggacc tgaaagggac tatccatcag aaaaataaag agcagagcgt tacgcagcag
      601 ctatcgttct atcatccttt caccgttgag ttctatcagt atcagcgcag tatgtccggg
      661 gcaaaatttg gcagagtgtt gctgccggta actttggcgc tggatattgt cactatgccg
      721 ctacagctac tgatcttcag tcgttaaaat tggattcagc agcaatgcct acgttcggat
      781 gctggcgttg ctgcacgggt gaaatgagcg cccaccatca ttgaaattcc cccaactatc
      841 ccccattcta gatccatagc gaaagcgcga tagagcgctt catttctttt ttagaccagg
      901 actgcgcata tgaccaatcc attactaacg tctttttcac tgccgccttt ttctgcaatt
      961 aaaccggagc atgtggtgcc tgcggtcacc aaagcgttgg ccgattgccg ggcggcggta
     1021 gaaggcgttg tggcgcatgg cgcgccgtat agctgggaaa acctctgcca gccgttggcg
     1081 gaagccgacg atgttctggg gcgtattttc tcgccaatta gccacttaaa ctcggtgaaa
     1141 aatagcccgg agctgcgtga agcctacgaa cagacgttac cgctgctgtc ggaatacagc
     1201 acctgggttg ggcaacatga aggactgtac aacgcgtacc gcgacctgcg cgacggcgat
     1261 cattacgcca ctctgaatac cgcgcagaag aaagcggttg ataacgcgct gcgtgatttt
     1321 gaactgtccg gcatcggcct gccgaaagag aaacagcagc gttacggtga aattgccacc
     1381 cgcctgtctg agctgggcaa ccagtacagc aataatgtgc tcgatgccac catgggctgg
     1441 acgaagctca tcaccgacga agccgagctg gcgggaatgc cggaaagcgc gctcgccgcc
     1501 gctaaagccc tggcggaagc caaagagcag gaaggttacc tgctgactct ggatatcccg
     1561 agctatctgc cagtgatgac ctactgcgac aaccaggcgt tgcgtgaaga gatgtatcgc
     1621 gcctattcca ctcgtgcctc cgatcagggg ccgaacgccg gtaagtggga taacagcccg
     1681 gtgatggaag aaattcttgc gctgcgccat gaactggcgc aactgctggg cttcgaaaat
     1741 tatgcccatg agtcactggc caccaagatg gcggaaaatc cgcagcaggt gctcgatttc
     1801 ttaaccgatc tggcgaaacg cgcccgtccg cagggggaaa aagagctggc ccagctgcgc
     1861 gccttcgcca aagccgaatt tggcgttgag gaactgcaac catgggatat cgcgtactac
     1921 agtgaaaagc aaaaacagca cctgtacagc atcagcgatg agcagctacg cccgtacttc
     1981 ccggaaaaca aagccgtgaa cggcctgttt gaagtggtga aacgtattta cggcatcacc
     2041 gccaaagagc gtactgatgt tgatgtctgg cacccggagg tgcgtttctt cgaactgtat
     2101 gacgaaaata acgagctgcg cggcagcttc taccttgacc tgtacgcgcg cgaacacaaa
     2161 cgcggcgggg cgtggatgga cgactgtgtc ggccagatgc gtaaagcgga tggcacattg
     2221 caaaagccgg tcgcttatct gacctgtaat ttcaaccgtc cggtgaacgg taaacccgct
     2281 ctgtttaccc atgacgaagt gatcaccctg ttccacgagt ttggtcatgg cctgcatcat
     2341 atgctgaccc gcattgagac cgccggggtc tccggtatca gcggcgtgcc gtgggatgcg
     2401 gtcgaactgc caagtcagtt tatggaaaac tggtgctggg agccagaagc gctggcgttt
     2461 atctccggcc actatgagac cggcgaaccg ctgccgaagg aactgctgga taaaatgctg
     2521 gcggcgaaaa actatcaggc ggcgctgttt attctgcgtc agctggagtt cggtctgttt
     2581 gatttccgtc tgcatgcgga atttaacccg cagcaaggag cgaaaattct tgatacgctc
     2641 tttgaaatta aaaaacaggt cgccgtggtg ccgtcaccga catggggccg tttcccacat
     2701 gcgttcagcc atatctttgc tggcggctat gcggcaggct actacagcta tctgtgggcc
     2761 gacgtactgg cggcggacgc ttattctcgc tttgaggagg aaggcatttt caaccgtgag
     2821 accggtcagt cgttccttga taacatcctg actcgcggtg gttctgaaga gccgatggaa
     2881 ctctttaaac gcttccgtgg ccgtgaacca cagctggacg cgatgctgga gcattacggg
     2941 attaaaggct gattttacgt gcaaatctgc ttaatggatg aaacgggcgc cacagacggc
     3001 gccttatctg ttctggctgc ccgctgggga ctggagcatg acgaagacaa cccgatggcg
     3061 ctggtattga cgccgcaaca tctggagctg cgcaagcgcg acgaaccgaa gctcggcggc
     3121 atttttgtcg attttgtcgg cggcgcgatg gcgcaccggc gcaagttcgg cggcgggcgc
     3181 ggcgaagcgg tggcgaaagc cgtcggtatc aaaggcgatt acctgccgga tgtggttgat
     3241 gccacggccg gactggggcg cgatgcgttt gtgctggcgt ccgtcggttg ccgcgtgcgg
     3301 atgctggagc gtaatccggt ggtcgccgcg ttgctcgacg acggcctgac gcgcggctac
     3361 gccgatgcgg acattggcgg ctggcttcag gagcgtttgc agttgattca tgcttccagc
     3421 ctgacggcgt taaccgatat cacgccgcgc ccgcaggtgg tctacctcga tccgatgttt
     3481 cctcaccggc agaaaagcgc gctggtgaag aaagagatgc gggtgtttca gtcgctggtg
     3541 gggccggatc tcgacgccga cggactgctg gaaccggcgc gtcagttggc gaccaaacgc
     3601 gtggtggtca aacgtcccga ttatgcgccg ccgctggcgg atgtcgcgac gcccaacgcc
     3661 atcgtcacca aagagcatcg gtttgatatt tatgccggaa cccctctgac ggagtaacgg
     3721 attgcccgat ggcgctacgc ttatcgggcc tacgattctc aattatttgt aggccggata
     3781 aggcgtaagc cgcatccggc actgagtatt actgttcggt accttgcgta ttaatcattc
     3841 ggtttaacca cggcaccata atggccatca ccacggtgac cgccagcgtt accagaccaa
     3901 ttttgctaaa gacgccggta taaatgggca gcgtctgtaa cggatcggtg atgttttccg
     3961 gtacggcagt gaaggtcgcc acataaccgc cgagcaggaa ggcggcggcc tgggtcagga
     4021 accacattcc cagaataaag cccatcagat gctgcggcac cagagcggcg accattgcca
     4081 gtcccagcgc gctaatcagc aactcgccca gactctggaa cagatacact agcacgataa
     4141 accacggcga cgtcaatcct tgcgcatcgg caaaccacat cccggcggcg gcggtcagaa
     4201 aacccagcgc gcagaggaac atgccgagcg taaacttcat cggcatagtc agatctttgc
     4261 ctttgctacc cagtcgggtg taaatcgctg ccagtaccgg actggcgacg accacccaga
     4321 atgggttcag cgcctgaaaa ctcaccgggt taatggcgaa tccaagaatt tcatgatgca
     4381 cgttattaat cgcaaagaag ttcagtgagg taggcatctg cgcatacaga atgtaaaaca
     4441 gcacggcttc aatcatcaga ataaacgcca cgaacatttt attgcggccg gttttatcca
     4501 gacgaaacgc ttcgcgaaag aagaaaatag tgacgacgat agaaaggacg atgagcacca
     4561 gattggcaat cttaacgttg tgcatcagcc aggcgcagag gaaaatcatg acgacggtgc
     4621 cgagtagtac cagcagcaaa ttgcgaaaac gtagcggttt atgatccggt tcagaaccga
     4681 tatttttcac catgccacgg caggcgaagt acaccagaag cgcaacaatt aaaccagcgc
     4741 cgcacagatt ataggtcacc gcatagccaa atttatcggc aatcaccggc gccagcgata
     4801 gcgataacaa agaaccgatg ttaatcgaca tataaaacag ggtgaaagcg ccatccagcc
     4861 ggggatcttt aggctgatag catttagaga gcaggctggc gggattggct ttaaataacc
     4921 cgttgcccac ggcaatcgta cccagtgcga taaaaatcag atcgggattt aatagcgaca
     4981 taccagtcat aaaatagcca atcgccagca caatcgcgcc caggaccagg gtgcgtttag
     5041 tccctaacag atggtcgcca acatagccgc cgatggagat caggccataa accagcgccg
     5101 caaaagcgcc aaaagtaata aaggcctgtt cctgagaaaa acccaattgt ttaacgaaaa
     5161 agaccgccag gatgccctgg acgccgtaat agctaaatcg ttcccataat tctacaaaaa
     5221 agatcatgaa gaatggacga ggttgctgca gcaagcccgt aggtgcagtt gtattcatat
     5281 tccttcgcct tttaatgcca tcccgaaacg tatgaacgcg tatatcaaaa cgcgccgaaa
     5341 agtcttaccc tgatatagac tgcggttatt agcctgatca ataggttatt atacaaatga
     5401 tacgcaaact aattagtgga tcacactaat tatgtttggt gtgatggaat gatgtactga
     5461 gtactgcgaa gaagggggga taaacaaaac gcccacataa gcgggcgttg ttgttgatag
     5521 ccggagtttg cctgatggtt caggccaacc tgattgacta tagaccagat gcggtcttag
     5581 ccgccagccg gcacggtaag tattactctt cttcgtcgcg cagcggaaca atcagcatgt
     5641 caacgtgaac ggtgttgatc agctggcgcg cagaagacat cagtttgctc cagaagtcct
     5701 ggtgatgacc gcaaacgacc agatccatat cgtatttctt gatggcgtca accagcacct
     5761 ggcccaaatc gccgctaccg ctcagggttt cagtgatagg gtagccagcg ttggtagaca
     5821 gctcggtcag cgcgtggtgg gtttctttgg agatacgttt ctgcatatcg cccagattga
     5881 cgtcaatcag accggtgtac aggtctgaat agttcacatc aacgtggatg agggagattt
     5941 tcgcgttgta ggggcgcgcc atagagaccg ctttttcaac cagaacttta ctttccgggg
     6001 agagatcaac tgcgataaga atgtgtttat aagccatagt gttactcctt ccataagttg
     6061 tcgatgacca ttgagctact ggcgtttctt atgccgccgc gtcacccgcg tcctgcgaac
     6121 tctatgcgcg gggctagctc agccgtttac cataactatc cttacattat agcgaccagg
     6181 ataatccgtc aatctgcctt gcttgccagt tagttaaaca aaattttcag ggaattgcat
     6241 tgatagtgat taaccttctg gtaaaaaaat taactgatct cctacaatgt gtataagagc
     6301 cgttcgaatg cggagcgcta atatggacgg ctttcgtagt actctttcac tgattgtctg
     6361 gcagggtatc ggggagcggt agtcccggag aggaactccg tgggcgggtc gccggggagg
     6421 agatatgata agcaccgtct cactattctg ggctttatgt gtcgtttgca ttgttaatat
     6481 ggcgcgctat ttctcatcgc tacgcgcact gttagtggta cttcgtggtt gcgatccttt
     6541 gctctatcaa tatgtcgatg gcggcggctt ctttaccacg catggtcagc ccaacaaaca
     6601 ggtgcgcctg gtatggtata tctacgctca gcgctatcgc gatcatcatg atgaagaatt
     6661 tattcgccgt tgtgaacgcg tgcgccgcca gtttctgctg accagcgcgt tatgcggttt
     6721 ggtggtggtg agcttgattg cgctcatgat ttggcactga ataaaaaaag cgggccagtt
     6781 tcctgacccg ctcgtattag ataagcctcc ggatgacgcc gcttgtagcg gcctgtcagg
     6841 cctgtgtcgt ttcatcctga caggccggat tagcgacagc gctatccggc ccatttggct
     6901 taaataatct tcagggaaag ccagtacagc acgccggaaa gaataatcgc cgccggtaac
     6961 gtaaataccc aggccatcag aatgctggtc acggttttac gctgtaaccc gccgccatca
     7021 acgaccatgg ttcccgccac tgaagaggag agtacgtgag tggtagaaac tggcataccg
     7081 gtgtagctgg caagaccgat agagactgcc gccgtcatct gcgccgacat tccctgcgca
     7141 tacgtcatgc cttttttacc aattttctcg ccgatagtgg tcgccacgcg acgccagccg
     7201 atcatcgtac caatacccag cgccaacgcc actgccataa tgatccacac cggcgcatac
     7261 tcaatggtgc ttaacatatc ggtcttcagc tttttcagca ggcgctggtc atcgctgctt
     7321 acgccaggca atttcacgac tttgtcggtc gtgtcggaaa tgcacagcat aatgcgacgc
     7381 aactgactac gctgttcaac gcttaacttg tcgtagcttt ccacgtttgc cagcatccct
     7441 ttcgcacggt taagcgcgtt aatggtgtta gccggatggc agtggaattc agtcggttca
     7501 gtcgcgcccg gttccggaga gggaatcagt tggtcaacgc cggtgacggc tttcagcagg
     7561 tcaggacgct gctcaaagta cgtttcgaca ttgttgatag catcgcgcgt acgggtgatt
     7621 tcgtagctgg aggcattcat attgaccacg aaacccgcag gcgcgacgcc aatcagcacc
     7681 agcatgacca ggccaatgcc tttctgacca tcgttcgcgc catgcgaaaa cgccacgccg
     7741 atagctgaga ggatcagcgc gatacgcgtc cagaatggcg gctttttctt gccgtctttc
     7801 ttttcacgtt cggctggcgt caggtggata cgggcgcgtt tcttagtacc gctccagtag
     7861 cggcgcagca agaaaatcag accgccggcg aataccagac cgacaatagg ggagataatg
     7921 agtgaaccga aaatattgat aactttcggg atgttaagcg catccaccac tgacgtgccg
     7981 gtcatcatcg cattggttaa accgatgccg ataatggcgc caatcagcgt gtgggaactg
     8041 gacgccggca acccgaaata ccaggtaccg aggttccaga taatcgccgc cagcaacatg
     8101 gaaaagacca tagcgaggcc gtgcgcggaa cccatgttga gcaggagatc cgtcggtagc
     8161 atatgcacaa tggcatacgc cacgctgaga ccccccagca aaacgccaaa aaagttaaac
     8221 accgccgcca tgacaaccgc cagctgcgaa cgcatcgcac gggtgtaaat cacggttgcg
     8281 actgcattgg ctgtatcatg gaaaccgtta atcgcttcgt agaacagcac aaaagccaga
     8341 gcaagcaata ataaaagccc ggtatgtaaa tccaggccag caaacaaatg tagcatagga
     8401 cgttacgcca ttttgaggac atgaacgcgg cgcattatca gtgactttgg cggcgcgggc
     8461 aaagtgaaat atagactttt tttgatgtac ttcgtgcttt gtttgatatc actaaagaat
     8521 tatcttatat atttcagata aataccattt tcaggcgctt ttcgcgctgg tgcgaccact
     8581 gaggaaactt tacaattctc gcccgaattt gagagaggaa ggcgacgtgg aaaggtttga
     8641 tgctgttatt ataggcgctg gcgcagcggg catgttttgc gccgcacagg caggacaagc
     8701 gggtagccgc gtgctgctca tcgataatgg caagaagcca ggacgtaaaa tcctcatgtc
     8761 cggcggtggg cgctgcaact ttactaatct ttatgttgag cctgctgcgt atttgagcca
     8821 gaacccccat ttttgcaaat cagcattagc ccgctatacc cagtgggact ttatcgatct
     8881 ggtcggcagg tatgggatag cctggcatga gaaaacgctg ggacagcttt tttgcgatga
     8941 ttccgcccaa cgcattgtcg atatgctggt tgccgagtgc gacaaaggtg gcgtaacgat
     9001 gcgcctgcgt agcgaggtat tgagcgtcga gcgtgatgag tcgggtttcg tactggcgtt
     9061 gaacggcgag acggtgacta cgcaaaagct ggtgattgcc agcggcggcc tgtcgatgcc
     9121 ggggcttggc gcatcgccgt ttggctataa aatcgccgaa cagtttggtc tcaaggtgtt
     9181 gccgacgcgc gccgggctgg tgccctttac gctacataag ccgctgttag aacagctcca
     9241 gacgctgtct ggcgtctctg tgccctgcgt gattaccgcc cgcaatggca cggtatttcg
     9301 ggaaaaccta ctttttaccc atcgtgggct gtccggcccc gccgttttac agatttccag
     9361 ctactggcaa ccgggcgagt tagtgagcat taacttattg ccggatctct cgctggaaga
     9421 cgttctcaat gaacagcgta acgcgcaccc gaaccagagt ctgaagaaca cgctggcgat
     9481 gcatctgccg aaacggctgg tggagtgttt acaacagttg gggctcatcc cggatgtatc
     9541 gctcaggcag ttgaacgttc gtgaccagca gacgttggtt gacacgctga cggcctggca
     9601 agtacagcct aacggtaccg aaggctatcg gacagcggaa gtgacgctgg gcggcgtgga
     9661 tacaaacgaa ctatcatcgc ggactatgga ggcgcgccgc gtgccgggtc tctattttat
     9721 cggcgaagtg atggacgtca ccggctggtt gggcggctat aacttccagt gggcctggtc
     9781 gagcgcctgg gcctgcgcgc aggatttgat tgcgttaaaa attaactaat tgatattatg
     9841 tgtttttcgg tctcatttga ctgatcgccg tatatcttgg cctatagcat cttttagtca
     9901 gaagtattct ggataagggg cactcatttt gcatggcatg accaccgatt tcgttttaac
     9961 aatggggaat gcggacggta gttttcgcta taaggtcgtg gcagtaaaac cagataaatt
    10021 ggtttcagct cgggagcctg
//
LOCUS       DAJVBX010000175         9855 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.175, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000175 DAJVBX010000000
VERSION     DAJVBX010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 9855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9855
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.175"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(82..909)
                     /gene="dkgA"
                     /locus_tag="OPV72_003582"
                     /pseudo
     CDS             complement(82..909)
                     /gene="dkgA"
                     /locus_tag="OPV72_003582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462080.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="2,5-didehydrogluconate reductase DkgA"
     gene            complement(1015..2178)
                     /gene="yqhD"
                     /locus_tag="OPV72_003583"
     CDS             complement(1015..2178)
                     /gene="yqhD"
                     /locus_tag="OPV72_003583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HCR9915783.1"
                     /translation="MKNFKLHTPTRILFGKGAIVDLRDQIPQDARVLITYGGGSVKKT
                     GVLAQVQDALKGLDVREFGGIEPNPSYETLMKAVQLVRDESITFLLAVGGGSVLDGTK
                     FIAAAAQYTDGVDPWHILETGGTEIRSAIPMGSVLTLPATGSESNAGAVISRKTTGDK
                     QAFHSSFVQPVFAVLDPVYTYTLPPRQVANGVVDAFVHTVEQYVTYPVNGKIQDRFAE
                     GILLTLIEEGPKALQEPENYDVRANVMWAATQALNGLIGAGVPQDWATHMLGHELTAM
                     HGLDHAQTLAIILPALWNEKRDVKRAKLLQYAERVWNITDGSDDERIDAAIAATRRFF
                     EQMGVPTHLSDYGLDGSTIPALLAKLEAHGCTNLGENQDITLDVSRRIYEAAR"
     gene            2371..3270
                     /locus_tag="OPV72_003584"
     CDS             2371..3270
                     /locus_tag="OPV72_003584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001407451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCR9915784.1"
                     /translation="MNREAICLQLADKINHLKNNDKIISERLAGIRLLYGVEPGPRTP
                     VMYQPGIIFLFSGHKIGYINKRKFRYDANEYLLLTVPLPFECETWATPEVPLAGIRLD
                     IDVLQLQELLMDIGEDERFQLPMAASGINSATLSDEILCAVERLLDVMEHPLDARILG
                     KQIIREILYHVLMGPRGGALLALVSRQTHFSLISRVLKQIEMKYTENLNVEQLAAEAN
                     MSVSAFHHNFKAVTSTSPLQYLKSYRLHKARMMMIHDGMKASAAAMRVGYESASQFSR
                     EFKRYFGVTPGEDAARMRTMQGS"
     gene            complement(3334..3993)
                     /locus_tag="OPV72_003585"
     CDS             complement(3334..3993)
                     /locus_tag="OPV72_003585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HCR9915785.1"
                     /translation="MAVIQDIIAALWQHDFAALANPHVVSVVYFVMFATLFLENGLLP
                     ASFLPGDSLLLLAGALIAQDVMHFLPTIGILTAAASLGCWLSYIQGRWLGNTRTVKGW
                     LAQLPAKYHQRATCMFDRHGLLALLAGRFLAFVRTLLPTMAGISGLSNRRFQFFNWLS
                     GLLWVTVVTSFGYALSMIPFVKRHEDQVMTFLMILPVALLVAGLLGTLVVVIKKKYCN
                     A"
     gene            complement(4133..5320)
                     /gene="metC"
                     /locus_tag="OPV72_003586"
     CDS             complement(4133..5320)
                     /gene="metC"
                     /locus_tag="OPV72_003586"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HCR9915786.1"
                     /translation="MTDKQLDTKLVNAGRSKKYTLGSVNSVIQRASSLVFDTVEAKKH
                     ATRNRANGELFYGRRGTLTHFSLQEAMCELEGGAGCALFPCGAAAVANTILAFVEQGD
                     HILMTNTAYEPSQDFCSKILGKLGVTTSWFDPLIGADITQHIQPNTKVVFLESPGSIT
                     MEVHDIPTIVSAVRRVAPDAVIMIDNTWAAGVLFKALEFDIDISIQAGTKYLIGHSDA
                     MVGTAVANARCWEQLRENAYLMGQMLDADTAYMTSRGLRTLGVRLRQHQESSLKIAAW
                     LANHSQVARVNHPALPGSKGHAFWKRDFTGSSGLFSFVLNKKLTEAELSAYLDNFSLF
                     SMAYSWGGYESLIIANQPEQIAAIRPAGGVDFTGTLVRVHIGLESVDDLIADLAAGFA
                     RIV"
     gene            5572..6306
                     /gene="exbB"
                     /locus_tag="OPV72_003587"
     CDS             5572..6306
                     /gene="exbB"
                     /locus_tag="OPV72_003587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tol-pal system-associated acyl-CoA thioesterase"
                     /protein_id="HCR9915787.1"
                     /translation="MGNNLMQTDLSVWGMYQHADIVVKCVMIGLILASVVTWAIFFSK
                     SVEFFTQKRRLKREQLQLADARSLDQASDIAAGFSAKSLSAQLINEAQNELELSQGSE
                     DNEGIKERTGFRLERRVAAVGRYMGRGNGYLATIGAISPFVGLFGTVWGIMNSFIGIA
                     QTQTTNLAVVAPGIAEALLATAIGLVAAIPAVVIYNIFARQIGSYKATLGDVAAQVLL
                     LQSRDLDLNASASAQPVRAAQKLRVG"
     gene            6313..6738
                     /gene="exbD"
                     /locus_tag="OPV72_003588"
     CDS             6313..6738
                     /gene="exbD"
                     /locus_tag="OPV72_003588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB system transport protein ExbD"
                     /protein_id="HCR9915788.1"
                     /translation="MAMRLNENLDDNGEMHEINVTPFIDVMLVLLIIFMVAAPLATVD
                     VKVNLPASTSTPQPRPEKPVYLSVKADNTMFIGNDPVTDDTMIAELTALTEGKKDTTI
                     FFRADKTVEYETLMKVMDMLHQAGYLKIGLVGEETAKAK"
     gene            complement(6851..7735)
                     /locus_tag="OPV72_003589"
     CDS             complement(6851..7735)
                     /locus_tag="OPV72_003589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCR9915789.1"
                     /translation="MSHLYDPTTQYYTGEYPKQKQPAPGVQAKMTPVPDCGEKSYVGS
                     GRLKDRKALVTGGDSGIGRAAAIAYAREGTDVAINYLPAEEEDAQQVKALIEECGRKA
                     VLLPGDLSDESFARSLVHKAREALGGLDILALVAGKQTAIPEIKDLTSEQFQQTFAVN
                     VFALFWITQEAIPLLPKGASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVA
                     EKGIRVNIVAPGPIWTALQISGGQTQDKIPQFGQQTPMKRAGQPAELAPVYVYLASQE
                     SSYVTAEVHGVCGGEHLG"
     gene            complement(7859..8263)
                     /locus_tag="OPV72_003590"
     CDS             complement(7859..8263)
                     /locus_tag="OPV72_003590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HCR9915790.1"
                     /translation="MKEVEDNNVYLALDNHKSDEFILKQNLAALIASKNATLEKVTQE
                     VVSIPAALVRLKWQNRREMYALQVKEEIYGATINAIIEQHPELRDKIMSRLESDWQHL
                     LARETATLRLTRKLSDGDYRTRNVTTVARQEK"
     gene            complement(8250..8660)
                     /locus_tag="OPV72_003591"
     CDS             complement(8250..8660)
                     /locus_tag="OPV72_003591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915791.1"
                     /translation="MLPEHLVSSHFRLSSPPPEATENSKNLSQGKTKLSDYEPDILIC
                     ANATGQHRNVLFEERDRHIKERLYCVAKIETFARLINALQAEGDIDAQTLSKILADKT
                     AMINEKGNAIWLNLITRETNMPLFYSLEDKDERS"
     gene            8752..9267
                     /locus_tag="OPV72_003592"
     CDS             8752..9267
                     /locus_tag="OPV72_003592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA helicase"
                     /protein_id="HCR9915792.1"
                     /translation="MEPAMNSIFYSVIILLLLTGAILFLMWEVNKKRPGGKTVNLNQT
                     EPMTKEEGEDHFSVLMNSITPVWYWRVNHEYIDFLHATIKRMTMTELNETPGLFDAQR
                     RCSDLNSAVYKYYDNIKKRCLNGEKVPYSDLDVLNLRQCFREFSLEAYPALVALVWPE
                     YQRPQVKPDEI"
     gene            9338..9832
                     /locus_tag="OPV72_003593"
     CDS             9338..9832
                     /locus_tag="OPV72_003593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00645 family protein"
                     /protein_id="HCR9915793.1"
                     /translation="MERFLENVMYASRWLLAPVYFGLSLALIALALKFFQEILHVLPN
                     VFALAEADLILVLLSLVDMTLVGGLLVMVMFSGYENFVSQLDISAGKEKLNWLGKMDA
                     TSLKNKVAASIVAISSIHLLRVFMDARNVPDNKLMWYVIIHLTFVLSAFVMGYLDRLT
                     RHNH"
BASE COUNT         2318 a         2443 c         2610 g         2484 t
ORIGIN      
        1 atgcgcgtaa ttgtttctta atgtttcgga atgcaaaaaa gcccgacgac atcgtcgggc
       61 atggcgtgcg ataaatccgg cttaaccgcc ggactgatcc ggatcgggcc cgaggcgttt
      121 tccttgatcc agttttgcga tctcgcctaa ttcatcttta tcgagacgga aatcccagac
      181 agcaaagttt tccgcgatac gggaaggagt gacggatttc ggaatgacta ccagcccgca
      241 gtccagatgc cagcgaataa caatctgggc gggcgttttg ccgtatttat ccgccagttc
      301 gcgaatcact ttctgatcga atacgccttc gccgccctgc gccagcgggc tccaggactc
      361 ggtctggatt ttatgcgtcg cattctacgc atgtagctgg cgctgttgca tcaaggggtg
      421 aagctcgatc tggttgatca cagggggaac gccggtttca tcgatcagac gctggaggtg
      481 atggatctga aagttacaga ccccgatact ctttaccagc ccctcttttt gcagcgcgat
      541 catgcccttc caggcgtcga catagtgatc gatagccggt acgggccagt gcatcagata
      601 gagatcgaga taatcaagtt gcagtttttt cagactctcc tgcagggctt cgcggggacg
      661 tttttgatcg tcattccaca acttagtggt gataaacagc tcttcccgcg ccacgctcgc
      721 tgcttttagc gctttgccga cgccttcttc attctgatat gctgtggcgg tatcaatcga
      781 tcgatagccc acctccagcg ctttatgaat cgccgcgatc acctcttcat tgcttgcttt
      841 ccagactccc agcccaagtt gtggcattac gttgccatcc tgtagcctga taatggttgg
      901 attagccatg atgtgttcct cttttaattg gctcgccgga gtcgggtccg gcgagactaa
      961 gtgacttaag tctggacgaa atggccaaaa acgaaagtca gaggcgaaaa aaccttagcg
     1021 cgccgcttca taaatccgac ggctgacatc cagcgtaata tcctgatttt cacctaaatt
     1081 tgtgcatcca tgcgcctcaa gtttggccag tagcgccgga atagtgctgc catccagacc
     1141 gtaatcggac aggtgggtag gcacgcccat ctgttcgaag aaacggcggg tggcggcaat
     1201 ggcggcatca atacgctcgt cgtcggaacc gtcggtgata ttccatacac gttcagcgta
     1261 ttgcaggagt tttgcgcgtt taacgtctcg tttttcgttc catagcgcag gcagaatgat
     1321 agccagcgtc tgggcatgat cgagaccgtg catcgccgta agctcatggc ccagcatatg
     1381 cgtcgcccag tcttgcggaa caccagcgcc aatcaggcca ttcaatgcct gagtagcggc
     1441 ccacatcacg ttagcgcgga cgtcatagtt ttcaggctct tgcagcgctt tgggaccttc
     1501 ttcgatcagt gtgagtaaaa taccttcggc gaaacgatcc tgaattttgc cgttaacggg
     1561 gtaagtgacg tactgctcaa cggtatggac gaaagcatcc acgacgccgt tcgcaacctg
     1621 gcgcggcggc aatgtatagg tgtagaccgg gtccagtacg gcaaacaccg gttgcacgaa
     1681 cgaggagtgg aaggcctgtt tgtcgccagt agttttacgg gaaatgactg cgccggcgtt
     1741 cgattctgag ccggttgccg gtagggtcag cacagacccc atcgggattg cgctacgaat
     1801 ctcagtaccg ccggtttcca gaatgtgcca cggatcgacg ccgtccgtat actgcgccgc
     1861 tgcggcgata aatttggtgc cgtccagtac ggaaccgccg ccaacggcca gcaggaaggt
     1921 aatactttcg tcgcgcacaa gctgcacggc cttcatcagc gtttcatagg acgggttcgg
     1981 ttcaataccg ccaaactccc gaacatccag tccttttaac gcgtcctgaa cttgcgccag
     2041 tacgccggtc tttttcacgc taccgccgcc ataggtaatc agcacgcggg cgtcctgcgg
     2101 gatctgatcg cggagatcga cgatagcgcc tttaccaaac agaatgcggg taggggtatg
     2161 taatttgaaa tttttcattg ctcattccct tatgtgggta aaaagagggc aggcggctgt
     2221 ctgcctgatg gtcatcattg tggtcttgtg agagatgtct ctcaatgcac atttctgcca
     2281 atgttttgcc tatttctcca gaatgctgga gaaaatcgct aaaaatgcgc acaatccagc
     2341 ggagtggatt tgataaaaaa atggcgcgtt atgaatcgtg aagcaatttg cttacagttg
     2401 gctgataaaa ttaatcattt aaaaaataat gataaaataa tcagcgagcg gctggcgggc
     2461 attcgtctgt tgtatggtgt tgaaccgggg ccgcgcacgc cggtcatgta tcagcctggc
     2521 atcatatttc tcttttccgg ccataaaatt ggctatatta acaagcgcaa gtttcgttat
     2581 gacgctaatg aatatctctt actgaccgtg ccgctccctt ttgaatgcga gacctgggcg
     2641 acgccggagg taccgctggc cggtattcgg ctcgacattg atgtgctgca actgcaagag
     2701 ttgctcatgg acattggcga agatgagcgt ttccagttgc cgatggcggc cagcgggatt
     2761 aactccgcca cgctgtcgga cgagatttta tgcgcggtgg aaagattgtt ggatgtgatg
     2821 gagcacccgc tggatgcgcg gattctggga aaacagatta ttcgcgaaat tctttatcat
     2881 gtgctgatgg ggccgcgcgg cggggcgctg cttgcgctgg ttagtcgcca gacgcacttt
     2941 agcctgatca gtcgcgtact taaacagatc gaaatgaaat acaccgagaa cctgaatgtt
     3001 gagcaactgg cggcagaagc gaacatgagc gtgtcggcgt ttcaccataa ttttaaggcg
     3061 gtcaccagca cctcgccgtt gcagtattta aaaagctacc gactgcataa agcgcggatg
     3121 atgatgattc acgacggtat gaaggccagc gccgcggcga tgcgggtcgg ctatgagagc
     3181 gcatcgcagt ttagccggga gtttaaacgt tattttggcg ttacgccggg cgaagatgcg
     3241 gcaagaatgc ggacaatgca agggagctaa gtggggcatc ccgccacggg gcaacgaagc
     3301 gtaaccgggc catcctggcc gattatggat acgtcaggcg ttacagtatt tctttttaat
     3361 caccacgacc agcgtaccta acagcccggc gaccagtagc gcgacgggaa ggatcattaa
     3421 aaatgtcatt acctggtctt catggcgctt aacaaacggg atcatactga gcgcgtagcc
     3481 gaagctggtc acgacagtca cccacagcag gccgcttaac cagttaaaaa actgaaaccg
     3541 gcggttggac aggccggaaa tgcccgccat tgttggcagc agcgtgcgga caaacgccag
     3601 aaagcgcccg gcaagcaacg ctaacaaacc gtgacggtca aacatgcagg tggcgcgctg
     3661 atgatatttt gccggaagct gcgctagcca gcctttgacg gtacgcgtat taccgagcca
     3721 gcgtccctgg atataactta gccagcagcc gagactggcc gcggcggtga gaatgccaat
     3781 cgtcggcaaa aaatgcatca catcctgggc gatcaacgcg cctgccagta gcagcagact
     3841 atcgccgggt aagaatgacg ctggcagcag accgttttct aaaaatagcg tggcgaacat
     3901 gacaaagtag acgacgctaa caacgtgtgg attcgccagc gcggcaaaat catgttgcca
     3961 gagcgcagcg ataatatctt gaatgacagc catgaacttt cctgtggaac agcatttacg
     4021 cttttatctg cctattgtac tcctgaatcg tccgggatgc cttgatcccg gacgcaacaa
     4081 acgcagactt ttccacggaa attgtctgca tatatgtcca tccacggcaa ctttacacaa
     4141 ttctggcgaa gccggcggct aaatcagcga tcaaatcatc aacactctct aaaccaatat
     4201 gcactcgaac cagcgtaccg gtaaaatcta cgccgcctgc gggacgaatc gcggcgatct
     4261 gttccggctg attagcaata atcagcgatt cgtagcctcc ccaggagtag gccatactga
     4321 acagcgaaaa gttatccaga taggctgata attctgcctc ggtcagcttt ttattgagca
     4381 caaaggagaa caggccgctg ctgcctgtaa agtctcgttt ccagaacgca tgacctttgc
     4441 tacccggcag ggccggatga ttaacgcgcg cgacctgaga atggttcgcc agccacgcgg
     4501 cgattttgag gctgctttct tgatgctggc gcagtcggac gccgagcgtg cgcagaccgc
     4561 ggctggtcat ataagccgtg tcggcgtcga gcatttgccc catcagatag gcgttttccc
     4621 gcaattgttc ccagcagcgc gcatttgcaa cggcagtacc gaccatcgca tcagaatgac
     4681 caattagata cttagtgccc gcctggatag agatatcaat atcgaattcc agagctttga
     4741 acagaacgcc agccgcccag gtattatcaa tcatgatgac ggcgtctggc gcgacgcgtc
     4801 tgaccgcact aacaatggtc ggaatatcat gtacttccat ggtaatagaa ccgggggatt
     4861 ccagaaatac gactttcgtg ttcggctgaa tatgttgcgt gatatcagcg ccgatgagcg
     4921 ggtcgaacca gcttgtcgtc acgcccagtt tgccgagaat tttgctgcag aaatcctggc
     4981 tgggttcata ggctgtgttg gtcatcagga tgtggtcgcc ctgttcaacg aatgccagaa
     5041 tggtgttggc gaccgccgcc gcaccgcacg ggaagagcgc gcatccggcg ccgccttcca
     5101 gttcacacat ggcttcctgg agcgaaaagt gagtcagcgt tccccggcgt ccgtaaaata
     5161 attcgccgtt ggcgcgattg cgggtagcgt gttttttggc ctcgacggtg tcaaacacca
     5221 gtgaagaagc gcgttgaatc acactattca ctgagccaag cgtgtatttt ttgctgcgtc
     5281 ctgcgtttac cagtttggta tccaactgtt tatccgtcat gttgcgtttc ctgattttaa
     5341 ccgtctggat gtctaaacta gcatgaatat aaccatctgc accctggcga tgtgtgatac
     5401 agatgaaaat tttgccaaaa taaaaacagg tggctttttt aatgcgtaag cgcaaagaaa
     5461 aagcagtaaa ggtgcggcag tatgtaaata gtaatgagaa cgactatcaa ttcgacgttg
     5521 ttttgatatt attatgctca gattttgtga tttgcgtcct ggagatacag agtgggtaat
     5581 aatttgatgc agacggatct ttccgtctgg ggcatgtatc agcacgccga tattgtcgtg
     5641 aagtgcgtga tgattggttt gattctggcg tcagtcgtca cctgggctat cttcttcagt
     5701 aaaagcgttg aatttttcac gcaaaagcgc cgcttaaagc gcgaacaact gcaattagcc
     5761 gatgcgcgct ctttagatca ggcttccgac attgcggcag gtttcagcgc aaaaagcctc
     5821 agcgcacagc tcatcaatga agcgcagaat gaactggaac tctctcaggg cagcgaagat
     5881 aacgaaggga ttaaagaacg taccggcttc cgtctggaac gtcgcgtcgc agcggttggc
     5941 cgctacatgg gacgaggcaa cggttatctg gcgacgatcg gcgccatttc ccccttcgtc
     6001 gggttgtttg gcaccgtatg gggcattatg aatagcttca tcggtattgc gcaaacgcag
     6061 accaccaacc tggcggtggt cgctcctggt attgcggaag cgctgctggc gacggcgatt
     6121 gggctggtag ccgcgatccc ggcggtcgtc atttacaaca tcttcgcacg tcagataggc
     6181 agttacaaag cgacgctggg cgacgtggcg gcgcaggtat tgctgctgca aagccgcgat
     6241 cttgatctga atgcgagcgc cagtgcgcag ccggtacgcg ccgcgcagaa attacgggta
     6301 gggtaatgcg tcatggcaat gcgtcttaac gagaacctgg atgacaacgg cgaaatgcat
     6361 gaaatcaacg tgacgccgtt tatcgatgtc atgttggttc tgctgattat ctttatggtg
     6421 gctgcgccgc tggcgacggt ggacgtcaag gtgaatctgc ccgcttctac cagtacgcca
     6481 cagccgcgtc cggaaaaacc ggtttatctg tcggtgaaag cggataacac catgtttatc
     6541 ggtaacgatc cggtgacgga tgatacgatg attgccgagc taacggccct gacggaaggg
     6601 aaaaaggata ctacgatttt cttccgtgcg gataaaaccg tagagtatga aaccctgatg
     6661 aaagtgatgg atatgctgca tcaggcgggc tatctcaaga ttggtttggt cggcgaagag
     6721 accgcgaaag cgaaataagt attctgctga tgctgtaggc cgggtaaggc gaagtcgcca
     6781 cccggctttt ttattgccta agatggcgcc ttgcttaaca gaattgcgcc accttaatcg
     6841 acttcatgcg ttagcctaaa tgttccccgc cgcacacgcc gtgcacttct gcggtaacgt
     6901 aacttgattc ctggcttgcc agatagacat acaccggcgc cagctctgcc ggttgaccgg
     6961 cccgcttcat tggcgtctgc tggccaaact gcggaatttt atcctgtgtt tggccgccgg
     7021 aaatttgcag cgctgtccag atagggccag gcgcgacaat attcacgcga attccttttt
     7081 ccgccacctg tttcgccagg ccgcggctgt aattaaggat tgccgccttg gttgccgcat
     7141 aatccagcag gtgcggactg ggctgatagg cctggataga cgacgttgtg ataatactgg
     7201 cgccttttgg cagcagcgga atcgcttcct gggttatcca gaacagggca aaaacgttaa
     7261 cggcgaaggt ttgctgaaat tgctcgctgg ttagatcttt tatctccggg attgccgtct
     7321 gtttaccggc taccagcgcc agaatgtcca gcccgcccag cgcttcgcgc gccttatgga
     7381 ccagcgaacg ggcgaaagat tcgtcgctaa gatcgcccgg caataacacc gctttacggc
     7441 cgcactcctc aatcagcgct ttaacctgct gggcgtcctc ttcttccgct ggcagatagt
     7501 tgatcgcgac atctgtgcct tcacgcgcgt aagcgatagc ggcagcgcgc ccaatcccgg
     7561 agtcgccccc tgtcaccagc gccttacgat ctttaaggcg accactgccg acataacttt
     7621 tttcaccaca gtcaggaaca ggcgtcattt tcgcctggac gccgggcgcc ggctgttttt
     7681 gcttaggata ctcgccggtg taatactgcg tggtagggtc gtatagatga gacattgagc
     7741 ttctcccttc aggttgaaca ccctttaagc gtagacactt ttactaccgt aagagggaga
     7801 atcagaacga tccttatgct tcgcccgtat tcacaacaga gttaactagc tatgaaggtt
     7861 atttttcttg ccgtgcgact gtggtgacgt tgcgcgtccg gtagtcgcca tcggaaagct
     7921 tacgcgtcag acgtaaggtt gccgtctcgc gagccagcag atgctgccag tcactttcaa
     7981 gacgagacat aattttgtct cgtaattcag gatgctgctc gataatagca ttgatggtcg
     8041 cgccataaat ctcctctttg acctgtaacg catacatctc tcgtcggttt tgccacttca
     8101 ggcgcactaa cgccgccggt atggatacca cttcctgcgt taccttttcc agagtggcat
     8161 ttttactggc gattagcgct gcaagatttt gctttaagat aaattcatca cttttatggt
     8221 tgtctaaagc caaataaacg ttattgtctt caacttcttt catctttatc ttccagtgaa
     8281 taaaatagcg gcatattggt ttcgcgagtg attaaattaa gccaaatggc attacctttt
     8341 tcatttatca ttgcggtttt atccgccagt attttactta gcgtttgggc atcaatatcg
     8401 ccttctgcct gtagtgcgtt tatcaggcgg gcaaacgttt caattttagc cacacaatac
     8461 agacgttctt taatatgacg gtcgcgttct tcaaataata cgtttctgtg ttgcccggtt
     8521 gcgttagcgc aaattaaaat atcgggctcg taatcgctga gttttgtctt tccctgagac
     8581 aaatttttac tgttttctgt ggcttcaggg ggcggcgatg acaggcgaaa atgagaggaa
     8641 accagatgct caggaagcat gactaaatat cctttacgat cagtggtata ctatttttaa
     8701 tagtgtaggt ttcgttgaca ataacatggt gtaattttaa aatcaaaaaa aatggagcct
     8761 gctatgaaca gtatttttta ttctgttatt atattgctat tactgaccgg cgcgatactc
     8821 ttcctgatgt gggaggttaa taaaaaacgt cctggtggaa aaaccgtaaa tttaaatcaa
     8881 actgaaccca tgacaaagga agagggcgaa gatcatttct cagtattaat gaattcgata
     8941 acgccggtat ggtactggcg cgttaaccat gaatatatcg atttccttca tgcaacgata
     9001 aaacgaatga caatgactga gttgaatgaa acgcctggat tatttgacgc acagcgtcgt
     9061 tgcagcgacc ttaactctgc cgtttataag tattacgaca atataaagaa gcgttgtctg
     9121 aacggagaaa aggtgccgta ttcggatttg gacgtcctta atttacgcca gtgttttcgt
     9181 gagttcagtc ttgaagccta cccggcgttg gtcgcgctgg tatggccgga atatcagcgc
     9241 ccacaggtta aaccggatga gatttaactg acatgttgat ctgatgttgt atggttgaga
     9301 tatactgttg ctggttttag ttacctgaca ggtccctatg gaacgctttc ttgaaaatgt
     9361 aatgtatgcg tctcgctggc tgctcgcgcc ggtgtatttt ggcctctctt tggcgctgat
     9421 cgctttagcg ctaaaatttt tccaggaaat tctacacgtt ctgccgaacg tttttgccct
     9481 ggcggaggcc gatctgatcc tggtgctgtt atcgctggtt gatatgacgc tggtcggcgg
     9541 gttgctggta atggtcatgt tctccgggta tgaaaacttt gtctctcagc tggatatctc
     9601 tgcgggcaag gagaagctga actggctggg gaaaatggat gcgacgtcgc taaaaaataa
     9661 ggtggcggca tcgatagttg ctatctcttc cattcacctg ttacgcgtgt ttatggatgc
     9721 gagaaacgtc ccggataaca aattaatgtg gtatgtcatc atccatctga cctttgtcct
     9781 gtcggcgttc gtgatgggct atctggacag attgacgcga cataaccatt gagccgccgt
     9841 ccacggcggg gcagt
//
LOCUS       DAJVBX010000176         9690 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.176, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000176 DAJVBX010000000
VERSION     DAJVBX010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 9690)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9690)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9690
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.176"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(303..392)
                     /gene="cbdX"
                     /locus_tag="OPV72_003594"
     CDS             complement(303..392)
                     /gene="cbdX"
                     /locus_tag="OPV72_003594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome bd-II oxidase subunit CbdX"
                     /protein_id="HCR9915794.1"
                     /translation="MWYLLWFVGILLMCSLSTLVLVWLESRQQ"
     gene            complement(405..1541)
                     /gene="appB"
                     /locus_tag="OPV72_003595"
     CDS             complement(405..1541)
                     /gene="appB"
                     /locus_tag="OPV72_003595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome d ubiquinol oxidase subunit II"
                     /protein_id="HCR9915795.1"
                     /translation="MLDYETLRFIWWLLIGVILVAFMVTDGFDMGVGCLLPLIARNDD
                     ERRVLINSVGAHWEGNQVWLILAGGALFAAWPRVYAAAFSGFYVAMILVLCALFLRPL
                     AFDYRGKIANARWRALWDTGLVIGSLVPPVVFGIAFGNLFLGVPFAFTPQLHVDYFGT
                     FWQLLSPFALLCGLLSLSLVIMQGGVWLQLKTEGVIRQRALSATRHSALLIVICFLLA
                     GYWLWAGVDGFVLLTQDANGPSNPLLKGVAILPGAWMNHFIRSPLLLIIPLLGMILPI
                     LAFYACLRGQTIRGFLFASLTQACVIFTAGITLFPFVMPSSVSPLSSLTVWDSTSSQM
                     TLEIMLVIVLIFLPIVLLYTLWSYYKMLGRINLETLRRNDHELY"
     gene            complement(1553..3097)
                     /gene="appC"
                     /locus_tag="OPV72_003596"
     CDS             complement(1553..3097)
                     /gene="appC"
                     /locus_tag="OPV72_003596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome bd-II oxidase subunit 1"
                     /protein_id="HCR9915796.1"
                     /translation="MWDVIDLSRWQFALTALYHFLFVPLTLGLIFLLAVMETIYVVTG
                     KTVYRDMTRFWGKLFGINFALGVAIGLTMEFQFGTNWSLYSNYVGDIFGAPLAMEALL
                     AFFLESTFVGLFFFGWQRLNKYQHLLVTWLVAFGSNISALWILNANGWMQYPTGAHFN
                     IDTLRMEMSSFSDLVFNPVSQVKFVHTVMSGYVTGAMFIMSISALYLLRGREREVALR
                     SFAIGSVFGTLAILGTLQLGDSSAYEVAQIQPVKLAAMEGEWQTEPAPAPFHLIAWPQ
                     QEQERNAFAVKIPALLGILATHSLDTPVPGLKNLMDDALPRLKRGREAWLLMQEIAQG
                     NRSPQVLNAFHAVEGDLGYGILLAKYAPDMNHVTPEQYRAAQRGAIPQVAPVFWSFRI
                     MVGCGSLLLVVMLIALIQTLRMRIDQHRWVLRMTLWSLPLPWIAIEAGWFMTEFGRQP
                     WAIQDILPTWYAHSALTPGQLAFSMGLILGLYTLFLIAEVYLMQKYARLGPSAMQHQQ
                     QAQQQG"
     gene            complement(3172..4020)
                     /locus_tag="OPV72_003597"
     CDS             complement(3172..4020)
                     /locus_tag="OPV72_003597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase expression/formation protein"
                     /protein_id="HCR9915797.1"
                     /translation="MSNAFFHLLGPGTQPDDASFSMNPLPLTCQVNGDPSMAALERCA
                     HSPAVMALLTDLRGQLARRIPEVGDVLGWELSPLNADDLSFLNTLLGEGEVSVRIQHP
                     DGSESEIQETIFCGLWRVRHLHNRRLLTDRLEAGSAPLTLWQAATADTLPDDSLLPPP
                     VAGLMNGLPLAHELLAHVRDPALQPHSINLTQLPLSEADRLFLARLCGHGNIQIRISG
                     YGESQINATALRHLWHVRCLDALKGPLLDSYEICPLPELVLAAPEDLADSRQRLDEVC
                     RWLETR"
     gene            complement(4017..4421)
                     /gene="hyaE"
                     /locus_tag="OPV72_003598"
     CDS             complement(4017..4421)
                     /gene="hyaE"
                     /locus_tag="OPV72_003598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase-1 operon protein HyaE"
                     /protein_id="HCR9915798.1"
                     /translation="MANDTPFSALWQRLLTRGWQPVEASTVDDWIKRIGDGVILLSSD
                     PRRTPEVSDNPVMIAELLREFPQFDWQVAVADLEQSEAIGDRFNVRRFPATLVFTDGE
                     LRGALSGIHPWAELLTLMRSMVDTPAAQETAQ"
     gene            complement(4411..5007)
                     /locus_tag="OPV72_003599"
     CDS             complement(4411..5007)
                     /locus_tag="OPV72_003599"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 1 maturation protease"
                     /protein_id="HCR9915799.1"
                     /translation="MNAQRVVVMGLGNLLWADEGFGIRVAERLYARYHWPEEVEIVDG
                     GTQGLNLLGYVEQASHLLLLDAIDYGLAPGSLRTYAGEKIPAYLSAKKMSLHQNSFSE
                     VLALADIRGHLPCHIALVGLQPALLDDYGGSLSEIARSQLPAAEQAALAQLAAWGIVP
                     QANEVARCLNYKCLSMENYEGVRIRQYQTRLEGKRSGE"
     gene            complement(5004..5735)
                     /gene="hyaC"
                     /locus_tag="OPV72_003600"
     CDS             complement(5004..5735)
                     /gene="hyaC"
                     /locus_tag="OPV72_003600"
                     /EC_number="1.12.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni/Fe-hydrogenase b-type cytochrome subunit"
                     /protein_id="HCR9915800.1"
                     /translation="MTGKLSPRVGEARDTAVSHYVFEAPVRLWHWLTVACMLVLMVTG
                     YFIGRPLPSVSGEATYLFYMGYIRLIHFAAAMIFIVLLLGRIYWACVGNRYSRELFIV
                     PVWRRSWWQGAFSVVRWYLFLEKKPGSDIGHNPIAQAAMFGYFLLSVFMILTGFALFG
                     EHSQYAIFAPFRYVVEFFYWTGGNSIDIHSWHRLGMWLIAAFIVGHVYLAIREDIMSD
                     DTVISTMINGYRSHKFPKPHDKEPS"
     gene            complement(5754..7547)
                     /gene="hyaB"
                     /locus_tag="OPV72_003601"
     CDS             complement(5754..7547)
                     /gene="hyaB"
                     /locus_tag="OPV72_003601"
                     /EC_number="1.12.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni/Fe-hydrogenase large subunit"
                     /protein_id="HCR9915801.1"
                     /translation="MSNQYQTQGYTVNDAGRRLIVDPITRIEGHMRCEVNIDEQNVIT
                     NAVSCGTMFRGLEIILQGRDPRDAWAFVERICGVCTGVHALASVYAIEDAIGIQVPDN
                     ANIIRNIMLATLWCHDHLVHFYQLAGMDWIDVLNALKADPRATSQLAQSLSAWPMSSP
                     GYFFDVQNRLKKFVDGGQLGIFRNGYWGHPQYKLSPEANLMGFAHYLEALDFQREIVK
                     IHTIFGGKNPHPNWIVGGMPCAINLDQSGAVGAINMERLNLVQSIITRTADFINNVMV
                     PDALAIGQFNKAWSQIGTGLSDKCVLSYGAFPDIANDFSQQSLLMPGGAVVNGDFKNV
                     MPVDLADPQQIQEFVDHAWYRYPDDRLGRHPFDGITDPWYNPGDVKGSDTHIQQLNEQ
                     ERYSWIKAPRWRGHAMEVGPLARTLIAYHKGDAATIESVDRMMSALKLPLSGIQSTLG
                     RILCRAHEAQWAVGKLQYFFDRLMTNLKNGDLATANTEKWEPASWPQHCRGIGFTEAP
                     RGALGHWASIRDQKIELYQCVVPTTWNASPRDPKKQIGAYEAALMGTQMAIPDQPLEI
                     LRTLHSFDPCLACSTHVLGDDGSELIAVQVR"
     gene            complement(7544..8662)
                     /locus_tag="OPV72_003602"
                     /pseudo
     CDS             complement(7544..8662)
                     /locus_tag="OPV72_003602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460742.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 1 small subunit"
     gene            9157..>9690
                     /locus_tag="OPV72_003603"
     CDS             9157..>9690
                     /locus_tag="OPV72_003603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HCR9915802.1"
                     /translation="MKNNIRFDLSDYLIHFFRDVDLETGSHIYLPEHCGFNNQHHACS
                     IDAKYLLRLSLRSHKIFSSWSYRNGQRTVYGDSPVVCFTDMPIAAYLETGVRRLERNE
                     NIGLYAIVLPKEQMFNYGARPVIYGLDQHNNARCSQGRYGERILDETALPLIEQYRYV
                     TYVPGKIDWTHEREWRWP"
BASE COUNT         2371 a         2637 c         2624 g         2058 t
ORIGIN      
        1 aacaattaac tcagatcaaa aatggcaggc agttggattt tcgttatgat tttggatgag
       61 aagtggttaa ctatccgcta taagaggtga tatatcgcta attatgcaat taattgctta
      121 aatatgcgtg atatgtgcaa ggcggctatt tgtcataatt atgacgcacc tctaaaagta
      181 aagattatga taacgacatg tatcaatgtt atgtcgtcct gtcggcgggg aaacgtcttc
      241 gccaggcgcg taaaaagata aaaataaccg gagtcagacg gctctgaccc cggtttacct
      301 ctttattgtt gacgcgactc aagccacacc agcaccagcg tcgacagtga gcacatcagc
      361 agaatgccga caaaccacag taaataccac atcgctctcg ctccctaata aagttcatga
      421 tcgttgcggc ggagggtctc caggttgata cgccccaaca ttttgtaata gctccacagc
      481 gtatagagca gtacgattgg cagaaaaatc agcacaatca ccagcatgat ttcgagcgtc
      541 atctggctgg aggtgctgtc ccacaccgtc aggctggaga gaggactaac actcgacggc
      601 atcacaaaag gaaatagcgt tatgccggcg gtaaagatga cgcaggcctg ggtcagggaa
      661 gcgaacagaa atccacgaat agtctgaccg cgaaggcagg catagaaagc cagaatcggc
      721 aggatcatac cgagcaacgg gatgatgagc agtagcggcg agcgtataaa gtggttcatc
      781 catgcgccag ggagtatcgc cacgcctttt aagagcggat tggaagggcc gttggcatcc
      841 tgcgtgagta agacaaagcc atcaacgccg gcccacagcc agtaaccggc cagcaggaag
      901 cagatcacga tcagcagcgc gctgtggcgg gtggccgaca gagcccgttg acgaataacg
      961 ccctccgttt tcaactgtaa ccagacgcct ccttgcataa tcaccaacga cagactcaat
     1021 aatccacaca gtagggcaaa gggcgagagt aactgccaga aggtgccaaa atagtcaaca
     1081 tgaagctgcg gcgtgaaggc aaacggcacg cctaaaaaca ggttgccgaa cgcgatgccg
     1141 aatacaacgg ggggcaccag gctgccgata accagaccgg tatcccacag cgcgcgccag
     1201 cgggcattgg cgattttacc ccgataatca aaggccagcg ggcgaaggaa gagggcacac
     1261 agcaccagga tcatcgccac ataaaaaccg gaaaacgcgg cggcatagac ccgtggccag
     1321 gcggcgaata atgccccgcc cgcgagaatc aaccatacct ggtttccttc ccagtgggcg
     1381 ccgacgctat tgatcaatac ccggcgttcg tcatcgttgc gcgctatcag cgggagcagg
     1441 caaccgacac ccatatcaaa cccgtcagtt accataaatg ccactaggat gacgccgatc
     1501 agcagccacc aaatgaaccg caacgtttca taatccaaca tgattgtctc ctttatccct
     1561 gttgttgcgc ttgttgttga tgttgcatgg cgctcggccc aagacgcgcg tacttctgca
     1621 tcagatagac ttccgcgatt aaaaacaggg tgtaaagtcc gaggataagc cccattgaga
     1681 aggccaactg gcccggcgtc agcgcggagt gagcgtacca ggtcggcaga atgtcctgaa
     1741 tcgcccaggg ctgacggcca aactccgtca taaaccaacc ggcttcaatg gcaatccacg
     1801 gtaacggcag gctccacagc gtcatacgca atacccagcg atgctggtcg atacgcattc
     1861 gcagcgtctg tatcaacgca atcaacatca ccactaacag cagcgaaccg cagccgacca
     1921 taatacggaa actccagaac accggcgcca cctgaggaat agcgccacgc tgggccgcac
     1981 gatactgctc cggcgtcaca tggttcatat ccggggcata tttcgccagc agaatgccgt
     2041 accccagatc gccctcaacg gcgtgaaacg cattcagtac ctgcggcgag cgattgcctt
     2101 gcgctatctc ctgcatgagt agccaggcct cccggccacg cttcaggcgc ggcagagcgt
     2161 cgtccatcag gttttttaac cccggaaccg gcgtatccag cgaatgggtg gccagaatac
     2221 ccagcagagc agggatcttc acggcaaatg cattacgctc ctgttcctgc tgcggccagg
     2281 caatcagatg aaacggcgcg ggcgcgggtt cggtttgcca ttcgccttcc atcgccgcca
     2341 gtttcaccgg ctgaatttgg gcgacctcgt aggccgaact gtcgcccagt tgcaaggttc
     2401 ccagaatggc cagggtgccg aatactgagc cgatagcaaa cgagcgcaag gccacctcac
     2461 gctcgcggcc acgtagcaga tacaaggcgc tgatagacat aataaacatg gcgccggtga
     2521 cataaccgga catgacggta tggacgaatt tcacctggct caccgggtta aagaccagat
     2581 cgctgaagct gctcatttcc atccgtaacg tatcgatgtt gaaatgagcg ccggtaggat
     2641 actgcatcca gccattggca ttcagaatcc ataatgctga aatattggag ccgaaggcca
     2701 ccagccaggt gaccagcagg tgttggtatt tattcagccg ctgccagccg aaaaagaaca
     2761 ggccgacaaa agtggattcg agaaagaagg ccagtaacgc ttccatcgcc agcggcgcgc
     2821 cgaagatatc gcccacatag ttggaataga gcgaccagtt agtcccgaac tgaaactcca
     2881 tggtcaggcc gatagccaca ccgagagcaa aattgatccc gaagagcttg ccccagaaac
     2941 gcgtcatatc gcggtagacg gttttccccg tcaccacata gatcgtctcc atgacggcca
     3001 gcaaaaaaat cagcccaagc gtaagaggaa caaataaaaa gtgatacagc gcggtcagcg
     3061 caaactgcca gcgcgataag tcaatgacat cccacatgct aactcctgta ggcagaaaga
     3121 gagtaaaaag ctaatcaata ccggacaccg gtgacgttcc tgttgagagc gctagcgcgt
     3181 ctccagccat cggcagactt catccaggcg ctggcgcgaa tcggccagat cttccggggc
     3241 cgccagtacc agctccggca aaggacaaat ctcatagcta tcgagcaacg gccctttaag
     3301 ggcgtccaga cagcgcacat gccagagatg gcgcaatgct gtggcgttga tttggctttc
     3361 gccatacccg gagatgcgaa tctggatgtt cccgtgtccg cataaacgcg ccagaaaaag
     3421 acgatcggcc tcgctgagcg gcagttgggt caaattgatg ctgtgaggtt gcaacgccgg
     3481 atcgcgtacg tgcgccaata actcatgggc cagcggcagt ccattcatca ggccagcgac
     3541 aggcggaggc agcagagagt cgtcaggcag cgtatcggca gtcgccgctt gccacaatgt
     3601 caggggcgcg ctacccgctt ccagacgatc cgtcagcaga cgtcggttat gcagatggcg
     3661 tacccgccac aggccgcaga agatggtctc ctggatctcg ctttcactcc cgtccggatg
     3721 ctgaatgcgt accgagactt cgccttcgcc caatagcgta ttgaggaatg agagatcatc
     3781 ggcattcagg ggagataact cccatcccag cacgtcgccg acttccggga tgcgccgggc
     3841 aagctgacct cgcagatcgg tcaacaatgc catcaccgcc gggctgtgag cgcagcgttc
     3901 cagcgccgcc atacttgggt cgccattgac ctgacaggtg agcggtaggg gattcatcga
     3961 gaaactggcg tcatcaggct gcgtgcctgg ccccagcaga tgaaaaaagg cgttgctcat
     4021 tgtgctgtct cctgcgctgc gggagtgtca accatcgaac gcatcagcgt gagcagttca
     4081 gcccagggat gaatgccgct gagcgcgccg cgtagctcgc cgtctgtaaa aaccaacgtc
     4141 gccggaaacc gacgtacatt aaagcgatcg ccgatagctt cgctttgttc aaggtcggcc
     4201 accgccacct gccagtcaaa ctgcgggaac tcacgcagga gttcggcaat catcaccggg
     4261 ttatcgctga cttccggcgt acgccgcgga tcgctactta acaggatgac gccatctcca
     4321 atccgtttga tccagtcgtc taccgtggaa gcctctaccg gttgccatcc acgggttaac
     4381 aggcgttgcc atagcgcaga gaacggggtg tcattcgcca cttcttttgc cctccagacg
     4441 tgtctgatac tgacgtatgc gcactccctc ataattttcc atcgacaggc atttatagtt
     4501 caggcagcgt gcgacctcat ttgcctgcgg tacgatcccc caggcggcca gttgcgccag
     4561 ggcggcctgt tctgccgccg gtagctggct gcgagctatt tcgctcaggc taccgccgta
     4621 gtcgtccagt agcgccggtt gcaggccgac cagcgcaatg tgacagggca gatgcccgcg
     4681 gatgtcggcc agcgccagaa cttcggaaaa actgttttga tgcaggctca tttttttggc
     4741 gctgagatac gcggggattt tctcgccggc ataggttcgc aggctgcccg gcgccaggcc
     4801 gtaatcgatc gcgtcaagga gcaggagatg gctggcttgc tcaacataac ctaacaggtt
     4861 tagcccttgc gtaccgccgt ccacaatttc tacctcttca ggccagtgat atcgggcata
     4921 caaacgctcc gcgacccgga taccgaatcc ttcatcggcc cacagcaggt ttcctaatcc
     4981 catcaccact acacgttgcg cattcatgag ggctccttgt cgtgcggttt ggggaatttg
     5041 tggctgcgat agccattgat catggtggag atcaccgtat cgtcggacat aatgtcttcc
     5101 cggatagcga ggtaaacgtg cccgacgatg aaggcggcga tcagccacat gcccagtcgg
     5161 tgccagctgt gaatatcgat ggagttgccg ccggtccagt agaaaaattc aaccacatag
     5221 cggaacggcg caaagatggc atactggcta tgctcgccaa acagagcgaa accggtgagg
     5281 atcataaata ccgataacag gaaatagccg aacatcgcgg cctgcgcgat aggattatgt
     5341 ccgatgtcgc tccccggttt tttctccaga aacagatacc agcggaccac ggagaaagcg
     5401 ccttgccacc aactgcgacg ccagaccggg acgataaaca gctctcgcga atagcggttg
     5461 ccgacacagg cccaataaat tcgccccagc agtaacacga taaagatcat cgcggcggca
     5521 aagtggatca gccggatata gcccatgtaa aacagatagg tcgcctcgcc actcaccgac
     5581 ggcagcggtc ggccaatgaa gtagcctgtt accatcagta ccaacatgca ggccaccgtt
     5641 agccagtgcc acaggcgtac cggcgcttca aacacatagt ggctgacggc agtatcacgc
     5701 gcctccccga cgcgtggaga tagctttcca gtcatcgttc ttttccttaa cgcttagcgt
     5761 acctggacgg caatcagttc gctgccgtcg tcgccgagca cgtgggttga acaggcgagg
     5821 caggggtcga agctgtgcag cgtcctcagg atttctaacg gttggtcggg aatcgccatt
     5881 tgcgttccca tcaatgccgc ttcataggcg ccgatctgtt ttttaggatc gcgtgggctg
     5941 gcgttccagg tggtggggac tacgcactga tagagttcaa tcttctgatc gcggattgac
     6001 gcccagtgtc ccaacgctcc acgaggcgct tcggtaaaac cgatgccgcg gcagtgctgc
     6061 ggccaactgg ccggttccca tttctcggta ttggcggtgg ccaggtcgcc gtttttcagg
     6121 ttggtcataa gcctgtcgaa aaaatactgc agcttaccga cggcccattg cgcttcgtgc
     6181 gcgcggcata aaatacggcc aagcgtagac tggataccgg agagcggcag tttaagggca
     6241 gacatcatgc gatctaccga ctctatggtg gcggcatccc ctttgtgata cgcgataagc
     6301 gttcgggcaa gcgggccgac ttccatggca tgaccccgcc agcgcggcgc tttaatccag
     6361 gagtagcgtt cctgctcgtt gagctgctgg atatgcgtat cgctgccttt gacatcaccc
     6421 gggttgtacc agggatcggt aatgccgtca aaaggatgac ggcccagccg atcgtccgga
     6481 tagcggtacc aggcatgatc cacaaactcc tgtatctgct gcggatcggc caaatctacc
     6541 ggcatgacat ttttaaaatc gccattgacc accgcgccgc ccggcattaa caggctttgc
     6601 tggctgaagt cgttggcaat gtccggaaat gcgccgtagc tcagcacgca tttatccgac
     6661 agaccggtgc caatttgact ccatgcttta ttgaactggc cgatagccag cgcgtccgga
     6721 accatcacgt tgttaatgaa gtcggcggtg cgggtgatga tcgactgcac caggttgagg
     6781 cgctccatat tgatagcccc gaccgcgccg ctttgatcga gattgatcgc gcacggcatc
     6841 ccgccgacga tccagttagg atgggggttc ttaccgccaa atatggtatg gattttgacg
     6901 atctcgcgct ggaagtcgag ggcttcaaga tagtgggcaa aacccatcag attagcctct
     6961 ggcgacagtt tgtactgtgg atgtccccaa tagccgttac ggaatatccc aagctggccg
     7021 ccatcgacaa atttcttcaa tcgattttgt acgtcaaaga agtagcccgg cgatgacatc
     7081 ggccaggcgg aaaggctttg cgccagctgc gaggtggcgc gtggatcggc tttcagcgca
     7141 ttcagaacat caatccagtc catgccggct aactgataaa aatggaccaa atgatcgtgg
     7201 caccacaacg tagccagcat gatgttacgt ataatattgg cgttatccgg tacctggata
     7261 ccaatcgcat cttcgatagc gtacaccgac gccagagcat gtaccccggt acagacacca
     7321 caaatacgtt caacaaacgc ccaggcgtca cgtgggtcac ggccttgcag aatgatctcc
     7381 agcccgcgga acatcgtgcc gcaggaaacg gcattggtaa tgacgttttg ctcatcaatg
     7441 ttcacttcgc agcgcatatg cccttcgatg cgggtaatcg ggtccacgat cagacgacgg
     7501 ccggcgtcgt taacggtata accctgggtt tgatactggt tactcatgcc tgtttatcct
     7561 cattgtccgg ctgttgttcg gcttgcgcta actgttgttt gtggcgttta cgttggttga
     7621 gcgcgctggc gacagcgtga ccgccaacgc ccgcagcgac cacgcccagc gcggtcagcc
     7681 ccaccgtatc ggcggttgaa tgggtaccca tctggggaat atccaccacg cggctataaa
     7741 acgagccgcg atcccagaaa ccattttctg aacatcccag acatccgtga ccggactgga
     7801 taggaaagga gacgccgtca ttccagcgtg tggaggagca ggcgttatag gtggttggcc
     7861 ctttacagcc catcttgtac aggcagtatc ccttgcgggc ggcgtcatca tcccagctct
     7921 cgacaaattc accggcatca aaatgggcgc gacggtagca tttatcgtgg atacgctgac
     7981 catagaacat cagtggacgg cccatgcgat cgagttccgg cagacgatca aacgtcacca
     8041 tataggtgat aatggcgctc atgacatccg ggattggtgg acatccaggg actttcacga
     8101 tcggcttgtc ggtgatcact ttatcgatag gcgttgcctg ggtcggattg gggcgggcgg
     8161 cctagacgca accccaggag gcgcagtttc cccaggcgat aatagcgctg gcgcccgcgg
     8221 cggctttctt cagtttttca ataaacgggc ggccgccgct gatacagaac attccttgct
     8281 ctcctaacgg cggattgcct tccaccgcca gaatgtattt cccggcgtag cgagtggtaa
     8341 tatcgtcaaa gacttcttcg gcctgtgcgc cggcggcggc catcagggtg tcgtcataat
     8401 cgagggaaat cagcgagagg atcacatctt tggctagcgg gtgcgaggaa cggataaagg
     8461 attcggtaca gcaggtgcat tccagtccat gaatccagac caccggaatc cgcggtttat
     8521 tctccagcgc ccaggcgatc tttggcgtca ttccggcgcc cagtcccagc gatgtggcgg
     8581 caaggctaca gaatttgaga aagctgcgtc gggtcactcc cttacgacgc atggcttgat
     8641 aaaaggtctc ctcgttattc ataacgcgta ttttttctcc tttttgcacc acgctccgcc
     8701 aggggcataa ggcgcttttg cgggtccgtt gacgttccgc cagcaaggta aatcattgtg
     8761 ttacgcgcga gcgcggaaac gagcccgatt cactttgcac cgacgtatac cgccagaaat
     8821 aatgtgaaaa aagcgtatcg gattaacgat aagaaacaat gtgaagtgtg tgggtatagc
     8881 ttatagcggt atatttatac ccattatcgg tttttcggcg aaagggccgt ggcggggaag
     8941 cgcggttgag tttgttccgg gatgaggttt tcagtgagca acctcaagtg gatttagcct
     9001 ggtctcgcca tttcagggat acgtaagttg atgcaaaagg agggaggatt tgatgtcatc
     9061 gttaaaagaa gcatacttcg tgatgatttt tatataaaat gatggtgctg gttttaaagg
     9121 aatgcaaaaa agagactgtt tgaaagaggg cgtcccatga aaaataacat cagatttgac
     9181 ttatccgatt atttgattca tttttttcgg gacgttgatt tagagaccgg tagccatatt
     9241 tatttacctg aacactgtgg ttttaataat cagcaccatg catgttccat tgatgctaaa
     9301 tatttactta gattatcttt acgcagtcat aaaattttct cgtcctggtc ataccgaaat
     9361 ggacaacgaa ccgtatatgg tgactccccg gtggtatgct ttacagatat gccgattgca
     9421 gcttatttag aaactggtgt tcgccgatta gaacgaaatg aaaatattgg tttatatgca
     9481 atcgttttac ctaaagagca aatgtttaat tatggggcaa ggccagtcat atatgggttg
     9541 gatcagcata acaatgctcg atgctcgcaa ggcagatatg gggaacgtat tcttgatgaa
     9601 acggctcttc ctctgattga acaatataga tatgttactt atgttccagg taagattgac
     9661 tggacacatg aacgcgaatg gcgatggcca
//
LOCUS       DAJVBX010000177         9623 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.177, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000177 DAJVBX010000000
VERSION     DAJVBX010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 9623)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9623)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9623
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.177"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..244
                     /locus_tag="OPV72_003604"
     CDS             <1..244
                     /locus_tag="OPV72_003604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF2170 family protein"
                     /protein_id="HCR9915803.1"
                     /translation="YICPVNTIRDTAEFNLFLLRNQKVLPLSSVGIALVKQEEYYVAF
                     GALSLNSSLADVTLEITTLVENALDIAEITQVYSQE"
     gene            259..957
                     /locus_tag="OPV72_003605"
                     /pseudo
     CDS             259..957
                     /locus_tag="OPV72_003605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463232.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PspA/IM30 family protein"
     gene            1181..1864
                     /locus_tag="OPV72_003606"
     CDS             1181..1864
                     /locus_tag="OPV72_003606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463234.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjfK family protein"
                     /protein_id="HCR9915804.1"
                     /translation="MARDRGSPMMQFFQRLLGKTSTPAPIRGPLGLHLNAGFTLDTLA
                     FRLLESSLLVALPGEKYTVAAASRIDLGGGSQIFRYYTSGDEFLQINTTGGTDVDDID
                     DIKLFVYEESFGINEERHWRSAIAPAAIGPMTLNWQERRWQRFFNHEEPGNIEPVYML
                     EKVENQQAEKWDVHNFTMGFQRQVTDDAWEYLLLNGEESFNERGEPEWVFSRALGVDI
                     PLTSLTVIG"
     gene            1882..2280
                     /locus_tag="OPV72_003607"
     CDS             1882..2280
                     /locus_tag="OPV72_003607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF350 domain-containing protein"
                     /protein_id="HCR9915805.1"
                     /translation="MHILDALLAFCAYFFIGAAMIIVFLFIYSKITPHNEWQLIKNNN
                     TAASLAFSGTLLGYVIPLSSAAINSVSIPDYFAWGGIALVIQLLIYGCVRLYMPTLSE
                     KIIHHNVAAGLFMGTAALAGGIFNAACMTW"
     gene            2290..2928
                     /locus_tag="OPV72_003608"
     CDS             2290..2928
                     /locus_tag="OPV72_003608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1190 domain-containing protein"
                     /protein_id="HCR9915806.1"
                     /translation="MAKKRKSRSTSGVGHSAIRRIAEPVNPFERQRNRYTPKYLTLAI
                     MGGAAFFLLKGYGDGSNSDNDGDGTFYATVNDCIDDGNSASVCADGWNNAKTEFYANV
                     PKQLTQESCQSQFGDCYFDITERSWVPVLSGFLLSRAIRQNRDEQYIYSSGGSSYVSR
                     PVWRTTSGDYAWRSGTGKSDTVTSPGYIIRKASTVSRGGYGRSSSARGHWGG"
     gene            2931..4094
                     /locus_tag="OPV72_003609"
     CDS             2931..4094
                     /locus_tag="OPV72_003609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathionylspermidine synthase family protein"
                     /protein_id="HCR9915807.1"
                     /translation="MLRHNVPVRRDLDKIACDHGFDFHVIDNEIYWDESRAYRFTLRQ
                     IEEQIEKPTAELHQMCLEVVERAVRDEQIMQQLAIPPLYWDVIAESWRSRDPSLYGRM
                     DFVWCGKDPVKLLEYNADTPTSLYESSYFQWLWLEDARRSGAIPRDADQYNAIQERLI
                     ARFSELYSREPLYFCCCEDTDEDRTTVLYLQDCAQQAGQETRFIYIEELGLGVGGVLT
                     DLDDNVIRRAFKLYPLEWMMRDDNGPLLRKRREQWIEPLWKSILSNKGLLPLLWRFFP
                     GHPNLLPAWFEGEKSLAAPGESSVRKPIYSREGGNVTIFDERQNVIDHADGDYADEPM
                     IYQAFQPLPRFGDSYTLIGSWIIDDEASGMGIREDNTLITKDTSRFVPHYIAG"
     gene            4179..5801
                     /locus_tag="OPV72_003610"
     CDS             4179..5801
                     /locus_tag="OPV72_003610"
                     /EC_number="1.3.8.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463238.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isovaleryl-CoA dehydrogenase"
                     /protein_id="HCR9915808.1"
                     /translation="MSWQTHTVFNQPAPLNNSNLFLSDGALCEAVSREGAGWDSDLLA
                     SIGQQLGTAESLELGRLANAHPPELLRYDPQGQRLDDVRFHPAWHLLMQGLCANRVHY
                     LAWEEEARAGSFVARAARFVLHAQVEAGTLCPVTMTFAATPLLLQMLPATFHDWLAPL
                     RSDRYDSHLLPGGQKRGLLIGMGMTEKQGGSDVLSNTTHAERLADDSYRLVGHKWFFS
                     VPQSDAHLVLAQAKGGLSCFFVPRFLPDGQRNSVRLERLKDKLGNRSNASAEVEFQDT
                     VGWRLGEEGEGIRHILKMGGMTRLDCALGSHGLMRRAFSVAIYHAHQRQAFGKPLIEQ
                     PLMRQTLSRMALCLEGQTALLFRLARAWEQRREAKEALWARLFTPAAKFAICKQGIPF
                     VAEAMEVLGGMGYCEESELPRLYREMPVNSIWEGSGNIMCLDVLRVLTKQHGVYDVLS
                     EAFAEVKGQDRHYDRAVRQLQQRLRKPDEAMGREITQQLFLLGCGAEMLRHASPPLAQ
                     AWCQMMLDTRGEMPLPAQVQNDLLLRATGGLR"
     gene            complement(5846..6121)
                     /locus_tag="OPV72_003611"
     CDS             complement(5846..6121)
                     /locus_tag="OPV72_003611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005134428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HCR9915809.1"
                     /translation="MKQELALSSLLLSAGLVSTTAQSAEFASADCVTGLNEIGLISVS
                     NVAGNPQDVERIIALKADEQGASWYRIIQMYEEQQSNNWRVQAILYA"
     gene            complement(6252..6581)
                     /gene="bsmA"
                     /locus_tag="OPV72_003612"
     CDS             complement(6252..6581)
                     /gene="bsmA"
                     /locus_tag="OPV72_003612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm peroxide resistance protein BsmA"
                     /protein_id="HCR9915810.1"
                     /translation="MIIRKRDRVMRRFAPLIAALLLSACSMLQGTPQPAPPVADHPQE
                     IRRDQTQGLQRMGTVSALVRGSPDDAIDEIRAKAAAAKADYYVILMVDETVVTGQWYS
                     QAILYRQ"
     gene            6765..7514
                     /gene="yjfP"
                     /locus_tag="OPV72_003613"
     CDS             6765..7514
                     /gene="yjfP"
                     /locus_tag="OPV72_003613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HCR9915811.1"
                     /translation="MIAIETRQLAGGVVLHAFPEGKRAVPLPCVVFYHGFTSSSLVYS
                     YFAVALAQAGFRVVMPDAPEHGARFGGDSQGRIHRFWQILHQNMQEFTTLRAAIQAEN
                     WLLDGRLAVGGASMGGMTALGIMTRHREVKCGASLMGSGYFTGLARTLFPPLSPQNPA
                     QQAEFDNIIAPLREWEVTHQLERLADRPLLLWHGQEDDVVPAIETFRLQQALAGAKLD
                     KHVTCLWAAGVRHRITPEALSATVAFFRQHL"
     gene            complement(7511..8266)
                     /gene="ulaR"
                     /locus_tag="OPV72_003614"
     CDS             complement(7511..8266)
                     /gene="ulaR"
                     /locus_tag="OPV72_003614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator UlaR"
                     /protein_id="HCR9915812.1"
                     /translation="MTEAQRHQILLDMLAQLGFVTVENVIERLGISPATARRDINKLD
                     ESGKLKKVRNGAEAITQQRPRWTPMNLHQAQNHDEKVRIAKAASQLVNPGESVVINCG
                     STAFLLGREMCGKPVQIITNYLPLANYLIDQEHDSVIIMGGQYNKSQSITLSPQGSEN
                     SLYAGHWMFTSGKGLTADGLYKTDMLTAMAEQKMLSVVGKLVALVDSSKIGERAGMLF
                     SRADQIAMLITGKNANPQVLQQLEAQGVSILRV"
     gene            complement(8371..9435)
                     /gene="ulaG"
                     /locus_tag="OPV72_003615"
     CDS             complement(8371..9435)
                     /gene="ulaG"
                     /locus_tag="OPV72_003615"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003856017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HCR9915813.1"
                     /translation="MSKVQSITRESWILSTFPEWGSWLNEEIEQEQVAPGTFAMWWLG
                     CTGIWLKSEGGTNVCVDFWCGTGKQSHGNPLMKTGHQMQRMAGVKKLQPNLRTTPFVL
                     DPFAIRQIDAVLATHDHNDHIDVNVAAAVMQNCADDVPFIGPQTCVDLWVGWGVPKER
                     CIVVKPGDVVKVKDIEIHALDAFDRTALITLPADQKAAGVLPDGMDVRAVNYLFKTPG
                     GNLYHSGDSHYSNYYAKHGNEHQIDVALGSYGENPRGITDKMTSADILRMAESLNTKV
                     VIPFHHDIWSNFQADPQEIRVLWEMKKDRLKYGFKPFIWQVGGKFTWPLDKDNFEYHY
                     PRGFDDCFTIEPDLPFKSFL"
BASE COUNT         2223 a         2392 c         2666 g         2342 t
ORIGIN      
        1 ttatatctgt ccggtaaata cgattagaga taccgcggaa tttaatcttt tcttgctgag
       61 aaatcagaag gttttaccgc tgtcttcggt cggtattgcc ctggtaaaac aggaggaata
      121 ttatgtcgct tttggcgcgt tgtcgttaaa ttcgtcgctt gccgacgtga cgctggaaat
      181 caccacgctt gtagaaaatg cgttggatat cgctgaaata acacaagtct attcacagga
      241 ataatacagg cggcttacat gggaatttta aaaagtttgt tcacgttagg taaatcattc
      301 gttgctcagg cagaagaagc cattgatgaa gcacagggtg tacgtatgct ggagcagcat
      361 attcgcgacg caaaagccga gctggataaa gcgggtaaat ccagagtgga tttattggcg
      421 cgggtgaagc taagccatga caagctgaat gatttacgtg cgcgtaaagt cagccttgaa
      481 acgcgggcgt tggcggcaat gagtaagaat gtcgacgccg ctttactcaa cgaagtggcg
      541 gaagaaatag cccgtctgga aaatgccatt cttgccgaag aacaggtgct gactaatctg
      601 gaagcctctc gtgatgcggt ggagaaggcc gtaacggcga caggccagcg gattgcgcag
      661 tttgagcagc aacttgaagt ggttaaggcg acagaagcca tgcagcgcgc gcagcaggcg
      721 gtgacgactt cgaccgtcgg agccgcgtcg aatgtgtcta cggcggcgga gccgcttaaa
      781 cgtttacaaa cgcgtcaggc tgaacgctag gcacggctgg atgccgccgc gcagctggaa
      841 aaagtcgccg atggacgcga cctggacgaa aaactggcgc aggcgggtat tggcgcaacc
      901 aataaaagca atgctcagga tgtgttggcg cgtttacagc gtcaacaagg cgaataatgc
      961 tctttacgtg gatggtcaaa acctgccagc gtcatttgtc cagactgacc tggcccgctt
     1021 tgctgggcct gtttatcggg cagtatctgc tttgctatct gtagcgcgaa agcgcgctac
     1081 cgtgctgagc ttcgtcgctt tcatacgaga cggcacatga atgcgcgatc tcaaatgaca
     1141 ttatgcccaa cgacaatcgc attctgtctg aagaggtcgc atggcaagag atagaggttc
     1201 ccctatgatg caattttttc agcgtttgct cggtaaaaca agcacgccag cgccgattcg
     1261 cggaccatta ggattacatc ttaacgccgg tttcacgctg gatacgctgg cattccggct
     1321 actagagtcg tcgttgctgg tggcgctacc aggtgaaaaa tacactgtcg cggcagcgag
     1381 tcgcatagat ttaggcggcg gcagtcagat ttttcgctac tacacctctg gcgatgagtt
     1441 tctacaaatt aacaccactg gcggcacgga tgttgacgac attgatgaca tcaaactttt
     1501 tgtatatgag gaaagtttcg gtattaacga ggaacgtcac tggcgttcag ccattgcgcc
     1561 agcggcaata gggccgatga cgctcaactg gcaagaacgg cgctggcagc gcttttttaa
     1621 ccatgaagag ccgggcaata ttgaacctgt ctacatgctg gaaaaggttg aaaatcagca
     1681 ggcagagaaa tgggacgttc acaattttac gatgggtttc cagcgccagg tgacggacga
     1741 cgcctgggag tatcttctat tgaacgggga agaatcattt aacgagcgcg gtgagcctga
     1801 atgggtgttt tcacgcgccc tcggcgtgga tatccctctc acttcactaa cggttattgg
     1861 ttaagcacat acagggaaat tatgcatata ctggacgcat tactggcttt ctgcgcctat
     1921 ttttttattg gcgcggcaat gatcattgta tttcttttta tttactcaaa gataacgccg
     1981 cataatgaat ggcagttgat aaaaaataac aatactgcgg catcgctggc ctttagtggt
     2041 acgttgctgg gctatgtcat ccccttatcc agcgcggcga taaactcagt cagcatcccg
     2101 gactattttg cctggggcgg cattgcgctg gtgattcagc tgctgattta tggttgcgta
     2161 aggttataca tgcctacgct gagcgaaaaa attattcatc acaacgtggc ggcggggcta
     2221 tttatgggaa ccgcagcgct ggctggcggt atttttaacg ctgcctgtat gacatggtaa
     2281 cggaagatca tggcaaaaaa acgaaaatcc agaagcacat ccggcgtagg ccattcggca
     2341 ataagacgga tagccgaacc ggtcaatccc tttgagcggc aacgaaatcg ctacacgcca
     2401 aaatacctga cgctggcgat tatgggtgga gcggcctttt ttctcctgaa agggtacggt
     2461 gacggcagca atagtgacaa cgacggcgat gggacgtttt acgccacggt gaacgactgt
     2521 attgacgatg gcaatagcgc cagcgtttgc gctgacggct ggaataatgc gaaaacagaa
     2581 ttttacgcta atgtgcctaa gcaattgacg caggagagct gtcagtcgca gtttggcgat
     2641 tgctactttg atatcaccga gcggagctgg gttccggtat taagcggctt tttactcagc
     2701 cgcgcgattc gtcagaaccg tgatgaacaa tacatctata gcagcggcgg ttcatcttac
     2761 gtctcccgtc ccgtctggcg caccacatcc ggcgattatg cgtggcgcag cggcacaggg
     2821 aaaagcgata ccgtgaccag ccctggttat atcatacgga aagcgtccac cgtctcccgc
     2881 ggcggctatg gccgttcttc cagcgcccgc gggcactggg gaggctaacc atgctacgac
     2941 ataacgtacc ggtacgccgg gatctggata agatcgcatg cgatcacggt tttgactttc
     3001 atgttatcga taacgaaatt tactgggatg aaagccgggc ctaccgtttt acattacggc
     3061 aaattgaaga acagatcgaa aaaccgaccg cagagcttca tcagatgtgt ctggaggttg
     3121 tcgagcgggc cgtccgggat gagcagatca tgcagcagct ggcgatcccg ccattgtact
     3181 gggatgtcat cgccgaaagt tggcgcagcc gcgatccttc gctttacggg cggatggatt
     3241 tcgtctggtg cggcaaagat ccggttaaat tgctggaata caacgcggat acgccgacat
     3301 cgctctatga gtcctcctac tttcaatggc tatggctgga ggatgctcgt cgtagcggcg
     3361 ccatcccgcg tgatgccgat caatacaacg cgatacagga gcggctgatc gcccgcttca
     3421 gcgagctgta cagtcgggaa ccgctctact tttgctgttg tgaagatacc gacgaagatc
     3481 gtacgacggt gctgtacctt caggattgcg cgcagcaggc gggccaggaa acgcgattta
     3541 tctatattga agaactgggg cttggcgtag gcggcgtgct gaccgatctg gacgataacg
     3601 tgattcgccg cgcctttaag ctctacccgc tggaatggat gatgcgcgat gacaacggcc
     3661 cgctattgcg aaaacgtcgt gagcaatgga ttgagccatt gtggaaaagt attctgagta
     3721 acaaagggct gttgccgtta ttgtggcgct ttttccctgg ccatccgaat cttctgccgg
     3781 cctggtttga gggcgaaaaa tcgctcgcag cgccaggtga aagtagcgta cggaagccga
     3841 tttattcacg tgaaggcggc aacgtcacga tttttgacga gcggcaaaat gttatcgatc
     3901 atgccgatgg cgactacgct gacgagccga tgatttacca ggcgtttcag cctttgccgc
     3961 gctttggcga tagctatacg ctgattggca gttggatcat tgacgatgaa gcctccggaa
     4021 tggggattcg cgaggacaat acgctaatta ccaaagacac ttcccgtttc gtcccacatt
     4081 atattgccgg ttaatcatac ttttgtgatc ttgctccggc gtcaatggcg cagtcatgac
     4141 catacttgac ttcagcgcca ttgaaggagg gagacaccat gtcctggcaa acacataccg
     4201 tctttaatca acctgctccg ctcaataaca gtaacttatt cctgtctgat ggcgcgctgt
     4261 gtgaagcggt ttcccgggaa ggcgcgggat gggatagcga tcttctcgcc agcattggcc
     4321 aacaactggg aacggcggaa tcactggaac tggggcgtct ggcgaacgcg catcctcctg
     4381 agttgctgcg ttacgatccc cagggacagc gcctggatga cgttcgcttt catcccgcct
     4441 ggcacctgtt gatgcagggg ctttgcgcta atagggtaca ttacctggcc tgggaggaag
     4501 aggcaagggc gggaagtttt gtcgcccggg cggcgcgttt tgtattacat gctcaggtag
     4561 aagcgggaac actctgtcct gtcacgatga cctttgccgc gacgccgttg ctattgcaga
     4621 tgcttcccgc cactttccat gactggctgg cgccgctgcg cagcgatcgc tacgattcgc
     4681 atttgctgcc gggcgggcaa aaacggggcc tgctcatcgg catgggaatg acggaaaagc
     4741 agggcggatc tgacgtactc agtaatacga cccacgcgga gcggctggcg gatgattcat
     4801 atcggctggt gggacataaa tggtttttct ctgtgccgca aagtgatgcg cacctcgtgc
     4861 tggcgcaggc aaaaggagga ctatcctgtt tctttgtgcc gcgtttcctg ccagacgggc
     4921 aacggaactc tgttcgtctt gagcgcctga aagataaact cggtaatcga tctaatgcca
     4981 gcgccgaggt cgagtttcag gataccgtcg gctggcggct gggagaagag ggcgaaggga
     5041 ttcggcatat cttaaagatg ggcggtatga cgcgtcttga ttgcgcgctc gggagtcatg
     5101 gcttaatgcg gcgcgcattt tcagtcgcca tttaccatgc tcatcagcgt caggcttttg
     5161 gtaagccgct gatcgaacaa ccgttgatgc gacaaacctt aagtcgtatg gcgctatgcc
     5221 tggaggggca gacggcgctt ttgtttcggc tggcgcgcgc ctgggagcaa cgtcgcgagg
     5281 cgaaagaggc attatgggcg cgattattca cgccagcggc gaaattcgcc atctgtaagc
     5341 agggaatccc ttttgtggct gaggcgatgg aggttctcgg cgggatgggg tattgcgaag
     5401 agagcgaact cccgcgcctg taccgtgaaa tgccggtgaa cagtatctgg gaaggttccg
     5461 gcaatatcat gtgtctggat gtacttcggg tgctgacaaa acaacacggc gtctatgacg
     5521 tattgagtga agcttttgcg gaagtcaaag gtcaggatcg ccattacgac cgcgcggtac
     5581 gccagctaca gcaacgttta cgcaaaccgg acgaagcaat gggcagagag attacgcagc
     5641 agcttttctt gctggggtgc ggagcggaaa tgctgcgtca tgcctcgccg ccgctggcgc
     5701 aagcgtggtg tcagatgatg ctggatacac gcggcgaaat gccgctgcct gcccaggtgc
     5761 aaaatgattt actgttaagg gcgaccgggg gactgcggta acgtttggcc tgtagtacat
     5821 gccatccggc gcgagccacg cggcatcagg catagagtat cgcctgtacg cgccagttat
     5881 tcgactgttg ttcttcatac atttgaataa ttctgtacca ggacgcaccc tgttcatcgg
     5941 ctttgagggc gataatccgc tccacatcct gtgggtttcc tgcaacatta ctgaccgaga
     6001 tcaggccgat ttcattcaga cccgttacgc agtcagcact ggcgaattcg gcagactgtg
     6061 ccgtcgtact caccagtccg gcagaaagca gcagtgagga taaggcaagt tcttgtttca
     6121 tcgtcagctc cttattacat accccgcatt taacaggacg ctccatcacg gtaaacctgt
     6181 ttgtttattg tgcacaggta aacgcatagg ggcgcaaagc aatgtaaaac tgactaaaaa
     6241 tcaatctact gttattgacg atataaaatg gcttgtgaat accactgtcc ggttacaacc
     6301 gtttcatcaa ccattaagat aacgtaataa tcggctttcg cagcggcggc tttcgctctg
     6361 atttcatcta ttgcatcatc cggggaaccc cgaaccagcg cgcttacggt ccccatccgc
     6421 tgtagtcctt gcgtttgatc gcgacggatt tcctgcgggt gatcggcgac aggcggcgca
     6481 ggttgcggcg taccctgcag catgctacac gcgcttaata acagcgctgc tatcaatgga
     6541 gcaaaccgac gcataactct atctcgtttc ctgataatca tagtgtaatg ccttattgat
     6601 ttccctttag ggggaatgtt cccgaagtgt tacctgtcac gcgattttcg aatgaaaacg
     6661 ttgcgaaagc gtaacccagt tctcaaacat tatgaattat tgcgctatcc ataaacttgc
     6721 gttaagtatt tctccgtggc ataccggata aaaaggagag aataatgata gcgattgaaa
     6781 cacgacaatt agccggaggc gtcgtactac atgccttccc ggaagggaaa cgcgccgtgc
     6841 cgcttccctg tgtggtgttc tatcatggct tcacctcctc cagcctggtt tatagttatt
     6901 ttgccgttgc cctggcacag gcaggattcc gggtagtcat gccggatgcg ccggagcatg
     6961 gcgctcgctt cggcggcgac tcacagggac ggatacaccg attctggcag attctgcacc
     7021 aaaacatgca ggaatttacg acgttacgtg cggcgattca ggcggaaaac tggctacttg
     7081 acgggcggtt ggcggtgggc ggcgcatcca tgggcggtat gacggcgctg ggcattatga
     7141 cgcgtcaccg tgaggtaaaa tgcggggcca gtttaatggg gtcgggctat tttaccgggc
     7201 ttgcccggac gcttttcccg ccgttatccc cgcagaaccc ggcacagcag gcggaattcg
     7261 acaatatcat cgcgccgcta cgtgaatggg aagtcacaca tcagttagag cgactggccg
     7321 acaggccgct tctgttgtgg catggtcagg aggatgacgt ggtgcctgct atcgaaacct
     7381 tccggctcca gcaggcactc gccggggcga agctggataa gcatgtgacc tgtttatggg
     7441 ccgcaggcgt gcggcatcgc attacgccag aagcgttgtc ggcgacggta gcgtttttcc
     7501 gacagcatct ttaaacgcgg agtatgctta caccctgggc ttcaagctgt tgcaaaacct
     7561 gcggattggc atttttgccg gtaatcagca tagcgatctg atcggctcgg ctgaacagca
     7621 ttcccgcgcg ctcgccaatt ttactgctat cgaccagcgc gaccagtttc ccgacgacgc
     7681 tgagcatttt ttgttccgcc atggcggtta gcatatcggt cttgtacagg ccatccgcag
     7741 ttaagccctt tccgctggta aacatccagt ggccagcata gagactgttt tcacttccct
     7801 gcgggctcag ggtaatcgac tggcttttgt tgtactgacc ccccatgata atcacgctgt
     7861 catgctcttg atcgatcaga taattcgcca gcggcagata gttggtaatg atctgtaccg
     7921 gcttcccgca catttcgcgc cccagcagga aagcggtgga gccgcagtta atcactacgc
     7981 tctcacccgg gtttaccagc tgcgacgccg ctttcgcgat gcgtactttt tcatcgtggt
     8041 tttgcgcctg gtgcagattc atcggcgtcc agcggggccg ctgttgggta atggcctctg
     8101 cgccgttgcg cactttttta agttttccgc tttcgtcgag cttgttgatg tcgcggcgcg
     8161 ccgtcgccgg ggagattccc agacgctcaa tcacgttttc gacggtaaca aagcccaact
     8221 gtgccagcat atccagcagt atttgatgtc tttgtgcttc agtcatgagc tattccgata
     8281 caaattgatt tgaaaagatg atatttgaaa tagcctggaa atactaaagt aaatggaaaa
     8341 aatgccgggt aatcccggca tgatatcgac tcacaggaag gatttgaatg gtagatcggg
     8401 ttcaatggta aagcaatcgt caaaaccacg cggatagtgg tattcgaaat tgtctttatc
     8461 caacggccag gtaaacttgc cgccaacctg ccagataaac ggtttaaaac catacttcag
     8521 gcgatctttc ttcatttccc ataacacgcg gatctcctgt ggatcggcct ggaagttcga
     8581 ccagatatcg tgatggaacg ggatcaccac tttggtgttc agcgactccg ccatgcgtag
     8641 aatatccgcg ctggtcattt tgtccgtaat accgcgcggg ttttcgccat aggaaccaag
     8701 cgcgacatca atttgatgtt cgttgccgtg tttcgcgtaa tagttggaat agtgagaatc
     8761 gccgctgtga tagagattgc cgcccggcgt tttaaacaga tagttaaccg cgcgtacatc
     8821 catgccgtcc ggcagtacgc cagcggcttt ctgatcggcg ggcagggtga ttaatgcggt
     8881 gcggtcaaag gcatcaagcg cgtgaatttc aatatctttc acttttacga catcgcccgg
     8941 ttttaccacg atgcagcgtt ctttcggcac gccccagcca acccataaat ccacgcaggt
     9001 ctgcgggccg ataaacggaa catcatcggc gcaattctgc attacggcag ccgcgacatt
     9061 gacgtcaatg tgatcgttat ggtcgtgggt cgccaggacg gcgtcgatct gacggatagc
     9121 gaaaggatcg agaacaaacg gcgtggtgcg caggttaggc tgtaattttt tgacgccagc
     9181 catacgctgc atctggtgac cggttttcat caacggatta ccgtggctct gtttaccggt
     9241 accgcaccag aaatcgacgc atacgttagt gccgccttca gattttagcc agatcccggt
     9301 acagcccagc caccacatag cgaacgtacc cggcgcgacc tgctcttgtt caatctcttc
     9361 gttcagccag cttccccact ccggaaacgt gctcagaatc catgattcac gcgtgatgct
     9421 ttgtacttta ctcatcgcat ttaccttcat gtttgttcaa aatggttcaa aacgtgattt
     9481 gttttgatta atcctgacac tattttctca agaaggcaat gggctatttt ttgacttttt
     9541 ggcaggagag aacgcagtca gaagaagatt taatcttgtc tggcgtcatg tgaatgttgg
     9601 catctttatg attttactta ttt
//
LOCUS       DAJVBX010000178         9622 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.178, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000178 DAJVBX010000000
VERSION     DAJVBX010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 9622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9622
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.178"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            2..334
                     /gene="umuD"
                     /locus_tag="OPV72_003616"
                     /pseudo
     CDS             2..334
                     /gene="umuD"
                     /locus_tag="OPV72_003616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490545.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translesion error-prone DNA polymerase V
                     autoproteolytic subunit"
     gene            complement(450..1475)
                     /locus_tag="OPV72_003617"
     CDS             complement(450..1475)
                     /locus_tag="OPV72_003617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCR9915814.1"
                     /translation="MSIRKQPNGKWLCECYPNGRDGKRVRKQFATKGEAIAFENHTMD
                     EVNKKPWLGEKEDRRHLSEVIEQWHSLYGQTLADPKRLLAKLSIICNGLGDPIASELT
                     AGDFTKYREARLKGEVKNEDGVLMSPVKPRTVNLEQRNLSSVFGTLKKLGHWPAPNPL
                     AGLPTFKIAEGELAFLAPEEIKRLLDACADSQSPSLLMIAKICLATGARWSEAENLQG
                     HQLSKYRITYTKTKGKKNRTVPISQELYDELPKNRGKLFTPCRKSFERAVKRAGIELP
                     EGQCTHVLRHTFASHFMMNGGNILVLRDILGHADIKMTMVYAHFAPDHLEDAVTKNPL
                     HNLNWKR"
     gene            complement(1479..2111)
                     /locus_tag="OPV72_003618"
     CDS             complement(1479..2111)
                     /locus_tag="OPV72_003618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR9915815.1"
                     /translation="MSLIKAGNDSGGRDAINRLIKAYNFSSRQQLCEHLEVSKSTMAN
                     RYLRDSFPAEWVIQCALETGISLLWLATGQGDMYACENEERNLKNETSVTVRPLSKIV
                     APSIKHVELKNGELQPSDEILLDSRLLDGDSSNSLFVKTATDSFVVDTSVKQVSNGFW
                     LVDMDGVKSIVKIARVPGNKIVVHQDETSFECSVDDIEAIGRAVKVIKSL"
     gene            2228..2470
                     /locus_tag="OPV72_003619"
     CDS             2228..2470
                     /locus_tag="OPV72_003619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006817401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HCR9915816.1"
                     /translation="MSTDISIRVPKEMATPAEFAEWEGISRGSVYQKIHHGQLAKYMV
                     KKEKNKGRVSLRYLMYKTDQVRESLGHSNFRVIVGQ"
     gene            2503..3012
                     /locus_tag="OPV72_003620"
     CDS             2503..3012
                     /locus_tag="OPV72_003620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory CII family protein"
                     /protein_id="HCR9915817.1"
                     /translation="MFDYKISKHPHFDEACRAFALRHNMAKLAERAGMKVQTLRNKLN
                     PEQPHQLTPSEIWLLTDITEDSTLVDGFLAQIHCLPCIPMNEVAKEKLPHYVMSATAE
                     IGRVAAGAVSGDVKTTAGRRDVISSINSVTRLMALAAVSMQARLQANPAMASAVDTVT
                     GLGASFGLI"
     gene            3020..3220
                     /locus_tag="OPV72_003621"
     CDS             3020..3220
                     /locus_tag="OPV72_003621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019077499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2724 domain-containing protein"
                     /protein_id="HCR9915818.1"
                     /translation="MLTKEPSFASLLVKQSPAMHCGHGWIMGKDGKRWHPCRSQDALL
                     AELSAKKQGKPWLLKVMLRLFR"
     gene            3184..3525
                     /locus_tag="OPV72_003622"
     CDS             3184..3525
                     /locus_tag="OPV72_003622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5347 domain-containing protein"
                     /protein_id="HCR9915819.1"
                     /translation="MAIEGDAATVPLSAGLRLNGLNHIAELRAKVFGLNIDSELDRFI
                     SDMRDQRDINHEQNKRALAAIFFMAKIPAERHSVNVSELTTDEKRELIKAMNHFRTVV
                     SLFPNRLAMPN"
     gene            3593..3826
                     /locus_tag="OPV72_003623"
     CDS             3593..3826
                     /locus_tag="OPV72_003623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2732 domain-containing protein"
                     /protein_id="HCR9915820.1"
                     /translation="MRNIETRITKTGPDDAGLNQMLTDARMEERRGRADVMAARLDSL
                     AARIVSRQLNHTEAAELLRQEAVKIQNEAQEIH"
     gene            3826..4053
                     /locus_tag="OPV72_003624"
     CDS             3826..4053
                     /locus_tag="OPV72_003624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA family transcriptional regulator"
                     /protein_id="HCR9915821.1"
                     /translation="MADSMDLVQQRVEEERQRHIHTARNKTPGVSRVLCIDCDAPIPP
                     ARRRAIPGVQCCVTCQEIAELKGKHYNGGAV"
     gene            4050..4634
                     /locus_tag="OPV72_003625"
     CDS             4050..4634
                     /locus_tag="OPV72_003625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001090717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HCR9915822.1"
                     /translation="MNTDKMTISQRANQWLDNDYLFIDTETTGLGDDAEIVEICIIDS
                     HGFIMLNTLIKPTKPIPDEAIAIHGITNEMVAFAPAWTDICGAVEELFRRFGFVIYNA
                     DFDLRLIRQTYALNERPSEGAPWMLAAHSVCAMKLYAEYRGEPGRFNGYKWHKLVDAA
                     AHEGVVVEGKAHRALADCKMTLGLVRALAKGGAK"
     gene            4631..5491
                     /locus_tag="OPV72_003626"
     CDS             4631..5491
                     /locus_tag="OPV72_003626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HCR9915823.1"
                     /translation="MSTILKWAGNKTAIMPELIKHLPAGQRLVEPFAGSCAVMMATDY
                     PHYLVADINPDLINLYKKIALDCEAFISRAKNIFAIANREVAYYNIRHEFNHSSEITD
                     FMKAVYFLYLNRHGYRGLCRYNLSGHFNVPYGNYKNPYFPENEIRAFAKKAQRATFIC
                     ASYDETLAMLRAGDVVYCDPPYDGTFSGYHTASFTGDDQYHLASILERRSSEGHPIIV
                     SNSDTSLTRSLYRNFTRHRIIAKRSMGVAAGDGKSATEIIATKLVRWFGVDLASGPDV
                     SVETEVRAWQ"
     gene            5482..7951
                     /locus_tag="OPV72_003627"
                     /pseudo
     CDS             5482..7951
                     /locus_tag="OPV72_003627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001749758.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication endonuclease"
     gene            8119..8307
                     /locus_tag="OPV72_003628"
     CDS             8119..8307
                     /locus_tag="OPV72_003628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915824.1"
                     /translation="MQDYILESLKLQRIDFFIKLVAASECSDEEKRLAIQWVSELTDE
                     LMAKIRSHEYCRSMDVTS"
     gene            8319..8552
                     /locus_tag="OPV72_003629"
     CDS             8319..8552
                     /locus_tag="OPV72_003629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinI family protein"
                     /protein_id="HCR9915825.1"
                     /translation="MRIEIMIDKEQKISQATLDALESELYRNLRPLYPKTAIRIRKGS
                     ANGVELSGLKLDEDKKRVMEIMQQVWEDDSWLH"
     gene            8648..8866
                     /locus_tag="OPV72_003630"
     CDS             8648..8866
                     /locus_tag="OPV72_003630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915826.1"
                     /translation="MKSHDRLRIVFAQARQNWRAFAYVMQVHENHYTKRAGVAGIRAR
                     AQRLTLGPKSLQAKKLTFIFQLELSAKK"
     gene            8876..>9622
                     /locus_tag="OPV72_003631"
     CDS             8876..>9622
                     /locus_tag="OPV72_003631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915827.1"
                     /translation="MAENGPIEDLAKRISEDLLSRFKWQQHGPCDRDFLCDDEAKHKP
                     EGKKQKHTHPVDVVFSYKDPYLNKVIYLNTDLKSYKAGSINASKIESALASLAKTIEC
                     ARYSPEWSEKYNFSQIDCEVRGLLFVFNHDNQLQHDFYEFFNPPKPAKGRRDKAVNLE
                     KIPLSAGQQIHIIDPFLINYMLAITNDMNDLIAKKEFPDEEYGFYYPQLTFHKVAVTE
                     KYLPATIEVLSSPFMVIKHGAVYKFNRAKGI"
BASE COUNT         2466 a         2251 c         2465 g         2440 t
ORIGIN      
        1 tattcccata gcatccattc ctgaagcact gacaatccct ttgtttacag agagatgtgc
       61 tgccggtttt ccttctccag caactgacta tacagaagaa gagctggatc tgaatgcgta
      121 ttgtatacgt cgccccagtt caactttctt tgttcgggcc attggtgatt cgatgcggga
      181 tatggggctg cattccggtg atctaatggt ggtcgataaa gccgaaaagc cgctacaggg
      241 tgacatcgtc attgcagaaa cagaaggtga gtttacagtc aaacgtctgc aacttaagcc
      301 ccgcatcgcc ctgcttccca tgaatcctgc ataccatttt tagtatagtt aaaacagtgt
      361 tttatgttta aaaacagcga gttagtatta ttaagtattt gtccgtttta cgcgttttta
      421 atgccctgcc gccaaaatgc cgccataaat tagcgcttcc aattgaggtt gtgaagcggg
      481 ttttttgtca cggcatcttc gaggtggtca ggggcaaagt gagcgtaaac catcgtcatt
      541 tttatatcgg catggcccag aatatcgcgc agtaccagta tgtttccgcc gttcatcata
      601 aaatggctgg cgaatgtatg gcgcagtacg tgagtgcact ggccttctgg cagttcgata
      661 ccagctcgct ttactgcacg ctcaaaggat tttctgcatg gcgtgaataa cttccccctg
      721 tttttaggga gttcatcata cagttcctga gatattggca cggttcggtt tttcttgcct
      781 ttggtcttgg tataagtgat gcggtatttt gatagctgat ggccctgcag gttttcggct
      841 tcactccatc gggcgccagt tgccaggcat atttttgcaa tcatcagcaa actgggactc
      901 tgcgaatcag cacaggcatc cagtagacgt ttaatttctt ccggtgccag gaacgccagt
      961 tcgccctctg cgattttgaa tgttggcagc ccagcgagcg ggttgggtgc tggccagtgg
     1021 cccagctttt tcagtgtgcc aaaaacagat gataggttac gttgttcaag gtttaccgta
     1081 cggggcttaa ctggcgacat aagcacgcca tcttcatttt ttacttcacc ttttaaccgt
     1141 gcttcccggt atttcgtaaa atcgcctgcg gttaactctg aggcaatggg atcgcccaaa
     1201 ccattacaaa taatgctgag ttttgccaac aggcgtttgg ggtctgccag cgtctgccca
     1261 taaagtgaat gccactgctc aatcacttct gacaaatgcc gccgatcttc tttctccccc
     1321 agccacggtt ttttgttcac ctcatccatg gtgtggtttt cgaatgctat ggcctcgcct
     1381 ttagtcgcaa attgcttgcg tacacgcttg ccatcccgtc cgttcgggta gcattcacac
     1441 aaccattttc cgttaggctg ttttctgatg ctcataagtt agaggctctt gattactttg
     1501 actgcacgcc cgatagcttc aatgtcgtcg accgagcatt caaatgatgt ttcatcttgg
     1561 tgaactacaa ttttgttgcc tggaacgcga gcgattttga cgatgctttt aactccgtcc
     1621 atatcgacta accagaagcc attactgact tgtttaacag acgtatccac aacaaagcta
     1681 tcagtagctg tttttacaaa caaagagttg gatgagtcac catcgagcag tctgctatca
     1741 agaagaattt catcacttgg ctgcagttca ccgttcttca gttcaacatg tttgatgcta
     1801 ggagcaacaa ttttagaaag tggtcttacc gtgacggagg tttcgttttt gagatttctt
     1861 tcttcgttct cacacgcata catatctcct tggcccgtag ccagccatag aagggaaatt
     1921 cctgtttcaa gagcgcattg aattacccat tcagcaggga aactatccct taagtatctg
     1981 ttagccatag tgctttttga tacttccaga tgttcgcaga gctgctgtcg tgagctgaaa
     2041 ttgtaagcct taataagcct gttaatcgca tcgcgcccac cactatcatt ccctgccttg
     2101 attaaactca taatcaaacc tcttgacgta tataaaaagt gatcttaata tccgctcatg
     2161 gtttgaaaag taaaatcaaa ccacataaaa caagataaaa cgaacccaaa ctaagagata
     2221 ctgcactatg agtactgata tttcaattcg tgtaccaaaa gagatggcaa cgcctgctga
     2281 gttcgcggag tgggaaggta tctcccgtgg ctcggtgtat caaaaaattc accatggtca
     2341 gcttgctaag tacatggtga agaaagaaaa aaataaagga cgtgtaagcc tgcggtacct
     2401 gatgtacaaa accgaccagg ttcgtgagtc tctgggtcat tccaacttcc gcgtcattgt
     2461 tggtcagtaa gttcgattat gagaactttc taaggggctt gcatgtttga ttataagatt
     2521 tccaaacatc cacactttga cgaagcctgc cgggctttcg cgctgcgtca caacatggcg
     2581 aagctggcag aacgcgcggg aatgaaagtc cagacgctgc gtaacaagct gaacccggaa
     2641 caaccgcatc agctcacgcc gtcggagatc tggctgctta ccgatattac tgaggactcc
     2701 acgctggtag atggtttcct ggcacagatt cactgcctgc catgcatacc gatgaacgaa
     2761 gtggcaaaag agaagctgcc gcattacgtc atgagcgcta ctgctgaaat cggacgtgtt
     2821 gctgccggtg ctgtatcggg tgatgtgaaa actactgcag gccgccgcga tgttatcagt
     2881 agcatcaact cagttactcg tctaatggca ctggctgccg tttccatgca ggcacgtttg
     2941 caggctaacc cggcgatggc aagcgcggtg gataccgtga cgggcctcgg cgcttcattc
     3001 ggtctgatct gaggtggcta tgctgactaa agaaccatct tttgcatcac ttctcgttaa
     3061 gcaaagtcct gcaatgcact gcggtcatgg ctggattatg gggaaggatg gcaagcgctg
     3121 gcatccgtgc cgctctcagg atgcgttgct ggctgagctg tccgctaaaa agcaggggaa
     3181 accatggcta ttgaaggtga tgctgcgact gttccgctaa gcgctggcct ccgtcttaat
     3241 gggttaaacc acatcgcgga attaagggcg aaagtgtttg gcttaaatat tgattcagaa
     3301 ctggatcgct ttattagcga tatgcgggac caacgggata ttaaccatga gcagaataaa
     3361 cgcgcactag ccgcaatatt ctttatggca aagattccgg cggaacgtca tagcgtcaat
     3421 gttagtgaac tgacgactga cgaaaagcgg gagctgatta aagcaatgaa ccatttccgt
     3481 acagtggtga gtttatttcc aaatcggcta gccatgccga attaaccaac aaccgaaatt
     3541 aaaggcgtaa acccgccggg cttcttattg cccaaattca ggagaaacaa caatgcgaaa
     3601 tattgaaacc cgaatcacca aaacaggacc agatgatgct ggccttaacc agatgctgac
     3661 tgatgcacgc atggaagaac gccgtggacg cgctgatgtg atggcagcac gtctggactc
     3721 tttggctgcc cgtatcgtgt cacgtcagct taaccacacg gaagcggctg agctgctgcg
     3781 tcaggaagcg gtgaagattc agaacgaagc gcaggagatc cactgatggc tgattcaatg
     3841 gacctcgtac agcagcgcgt tgaagaagaa cgccagcgcc acattcacac cgcccgcaat
     3901 aaaacgccgg gcgtttcccg tgttctctgc attgattgcg atgcaccgat cccgccagca
     3961 cgccgccgcg ccattccggg cgtgcagtgc tgcgtcacct gtcaggaaat cgcagagctg
     4021 aaaggcaaac actacaatgg aggtgctgta tgaataccga taagatgaca attagccaac
     4081 gtgcaaatca atggcttgat aatgactact tatttattga taccgaaacg accgggttgg
     4141 gtgatgatgc ggaaatagtt gaaatatgca ttattgatag tcatgggttt attatgctta
     4201 atacgcttat taagcccact aagcctatcc ctgatgaagc aatagcaatt catggaatta
     4261 ctaatgaaat ggttgctttt gcccctgcct ggactgatat atgcggggca gtggaggaac
     4321 tatttcggcg ctttgggttt gttatctata acgccgattt tgatctccgg ttaattcgtc
     4381 agacctacgc attgaatgaa agaccttctg aaggtgcgcc atggatgctt gctgctcatt
     4441 ctgtttgcgc gatgaagctt tatgcagagt atcgaggcga gccgggacga tttaatggct
     4501 ataaatggca taagctggtt gatgctgctg cgcatgaagg tgttgtagtt gaaggtaagg
     4561 cgcaccgtgc tttagctgat tgcaaaatga cgttagggct tgtccgtgct ctggctaaag
     4621 gtggtgctaa atgagcacca tcctgaaatg ggcgggaaat aaaaccgcca tcatgccgga
     4681 actgattaag catctgcctg caggtcagcg actggtggag ccgttcgccg gttcctgtgc
     4741 tgtgatgatg gcaacagact atcctcatta tcttgtcgcg gatattaatc cagatcttat
     4801 caatctctat aaaaaaattg cccttgattg tgaagctttc atatcacgcg caaagaatat
     4861 ttttgcgatt gcgaatagag aagttgctta ttacaacatt aggcatgaat ttaatcattc
     4921 ctctgaaatt actgatttca tgaaagcagt atatttcctt tatctcaatc gtcatggtta
     4981 tcgtggactg tgccgctata acctgagcgg tcattttaat gtcccttacg gtaattataa
     5041 aaatccgtac ttccctgaaa acgaaatacg tgcttttgca aaaaaggcac aacgcgcaac
     5101 gtttatctgc gccagctatg atgagacgct ggcaatgctg cgggcggggg atgtggttta
     5161 ttgtgatccg ccatatgacg gcacatttag cggttatcac actgccagtt ttaccgggga
     5221 cgatcagtac catctggcgt ctattcttga acgccggtca tcagaaggtc atccgattat
     5281 tgtgtccaac agcgacacct ctctgacacg ttccttatat cgtaatttca cccgccaccg
     5341 catcatcgca aagcgcagca tgggtgtggc tgcaggtgat ggtaaatctg caacagaaat
     5401 catcgctacg aagttagtgc gctggttcgg tgttgatttg gcgtctggtc ctgatgtctc
     5461 ggtggaaact gaggtgcggg cgtggcagtg agtaaaatca cattacatta tgcacaaacc
     5521 accggcggct cgaatgaggc cgccgcagcc tttccatgga ataccccaaa aaaagcggtt
     5581 aacccgtatc tggacccggc ggaatttgcg ccggagtctg cgctttcaaa cctgatcgct
     5641 ctttacgctg tggataacga gcaggagcag ttgcgccgtg agacgctgag cgatgaggtc
     5701 tgggagcgct atttcttcaa tgaatcccgt gatcctgtcc agcgtgaaat ggagcaggat
     5761 cggctgatta accatgccaa aacggcgcgc gagcagcagc gttttaatcc cgatctggtc
     5821 attattgcca acgtgggcgc ccaaccggcg catatcagca agcctctgct ggagcggatt
     5881 aaatatttcc atagtctggg cagagcaaaa gcttattccc gctacctgca aaaaacaatc
     5941 aggccgtgtc ttgagcggct ggagcgcgtg cgcgacagtc aggtatctgc ctctttccgg
     6001 ttcatggcga gtcatgacgg gctggagggg ctgctggtac tccctgaaat gaatcaggat
     6061 caggttaaac gcctatccac gctggttgcg gcacatatga gcatgtgtct tgatgcagcc
     6121 tgcggtgatc tgtttgtcag tgatgatgtt aaaccagaag aaattcgtca ggcatgggaa
     6181 agggttgctg cagaggccat gcgccttgag gtcatcccgc ctgcgtttga gcagttgcgc
     6241 cgcaaaaagc gccgccgtaa gccggtgcct tatgaactga tcccaccgtc gctggcccgt
     6301 atgctgtgcg cggactggtg gtatcgcaaa ttgtggcaga tgcgctgcga gtggcgggag
     6361 gagcagttgc gcgccgtctg cctggtcaac aagaaagcct caccgtatgt cagctacgaa
     6421 gccgtgatcc acaaacgcga gcagcgccgc aaatcgctgg agttcttccg ctcgcatgag
     6481 ctgatcaacg aagacggcga cacgctggac atggaagacg tggtgaacgc cagcaacagc
     6541 aacccggcgc accgccgtaa tgaaatgatg gcctgtgtta aggggctgga gctgatcgcg
     6601 gaaatgcgcg gagactgcgc ggtgttttat accatcacct gcccgtcacg cttccacgca
     6661 accctcaaca acggcaggcc taatccgaag tggaccagtg ccactgtccg gcagagcagt
     6721 gactatctgg ttgatacgtt cgccgctttc cgcaaggcaa tgcacaaggc cgggctgcgc
     6781 tggtatggcg tccgcgttgc agagccgcac catgacggca ccgtgcactg gcatcttctg
     6841 tgcttcatgc gcaaaaaaga ccgccgttcc atcaccgcgc tgttgcgtaa gtttgccatc
     6901 cgtgaagacc gcgaggagct gggcgccaat accgggccgc gcttcaagcc cgagctaatc
     6961 aacccgcgca agggtacgcc gacaagctac atcgccaaat acatcagcaa gaacatcgac
     7021 gggcgcgggc tggctaaaga aatcagcaaa gaaaccggca gatcactgcg tgacagcgcc
     7081 gagcatgtca gcgcctgggc gtcactgcat cgtgtccagc agttccgttt ctttggtatt
     7141 ccggggcgtc aggcataccg cgagctgcgc ttgctggctg gtcaggcggc gagagtgcag
     7201 ggcgaacgca aagcgggtgc gccggtactg gataatccgc gtctggatgc ggtactggcg
     7261 gcggctgatg cgggctgctt tgccacctat atcatgaagc agggcggtgt gctggttccc
     7321 cgcaaacatc accttgtccg cacggcatat gagcttaacg atgagccgag cgcctacggc
     7381 gatcacggta tccgtatata tggcatctgg tccccgattg cggagggcaa gatttgcacg
     7441 cacgcggtga agtggaaaaa ggttcgtaaa gccgttgacg ttcaggaggc ggcagccgac
     7501 cagggcgctt gcgccccttg gactcggtaa agccgttgac gttcaggagg cggcagccga
     7561 ccagggcgct tgcgcccctt ggactcggac tcgtggcaat aactgtcccc ctgttgaaaa
     7621 tctgaacaaa tcagggggtg atttacccga tattaaaacc atgaatgaga aggaactgca
     7681 ggattatctc cacaatatgg gccagaagga acggcgggaa cttacagcca ggttgagact
     7741 ggtaaaaccg aagcggaaaa cagtatacaa acagaatatt tcggagcagc aacgcctgca
     7801 gcttgaggca gaactgacag ccagagggtt tgaaggtagt gcatctgaga ttgatttgct
     7861 tctgcgtggt ggcagcattc cgtcaggtgc cgggctacgg attttttacc gcaaccatcg
     7921 actgcaggaa gatgacaaat ggcgtcagtg atactgacgg caaggcttta acaattcatg
     7981 ctcttaacga ccttcgtaag aacgttctca ttgacggata aaaaatattt tacttttgga
     8041 tatcaggggt acactgtata tataaacagt ggatatacat acagttaatg cgtatccgag
     8101 gtcgtgatag gagggaagat gcaggactat attttggagt cgttgaagct ccagcgcatt
     8161 gattttttta ttaagcttgt agcggctagt gagtgcagcg acgaagaaaa gcggctggct
     8221 atccagtggg tgtcagaact gaccgacgag ctgatggcga aaatccgcag ccatgaatac
     8281 tgccggtcaa tggacgtaac cagttaaggg aaatctgtat gcgcattgaa ataatgatcg
     8341 ataaagagca gaagattagc caggctacac tggacgccct tgaatccgag ctttaccgta
     8401 atttgcgccc tctgtatccc aaaacagcaa ttcgtatccg caagggcagc gccaatggtg
     8461 ttgaactgag cgggttaaaa ctggatgaag acaaaaagcg agtgatggaa ataatgcagc
     8521 aggtctggga ggacgacagc tggttacatt agcgaacgtt gcggacgata aaactggttt
     8581 ttaccgtccg caaggttgaa caacgagcca cgtgaggcgt tagcgctgtt gtgcatgtct
     8641 atgccgcatg aaatcgcatg atcgtttgag gatcgttttt gctcaggccc gccagaactg
     8701 gcgggctttt gcttatgtca tgcaggtgca tgaaaaccac tacacaaagc gggcaggcgt
     8761 ggcggggata cgagcgcgcg ctcagcgtct cacgttaggt ccaaagtcct tgcaagcaaa
     8821 aaagcttacc tttatctttc aattagaatt gtctgcaaaa aagtaaggaa atcaaatggc
     8881 agagaacggc cctattgaag atttggcgaa acgcatatcg gaggatctac tgagtcgatt
     8941 taagtggcag cagcatggcc cctgcgaccg agatttcctt tgtgatgatg aggctaaaca
     9001 taagcctgaa ggtaagaagc agaagcacac gcatcctgta gatgttgtat ttagttataa
     9061 agacccatat ttaaacaaag ttatttattt aaatactgat ttaaaaagtt ataaagcagg
     9121 ttcaataaat gcgtcaaaaa tagaatctgc attggcgtca ttagcaaaaa ctattgaatg
     9181 tgctcgctat agtcctgagt ggtcagaaaa atataatttt tctcaaattg actgtgaagt
     9241 tcgcggttta ctgtttgttt ttaatcatga taatcagttg cagcatgatt tttatgagtt
     9301 ttttaatcct cccaaacccg ctaaaggaag aagagataag gctgtcaact tagaaaagat
     9361 tcctttatcc gcaggtcagc aaattcatat aatcgatccg tttctgatta attatatgtt
     9421 ggcaataacg aatgatatga atgatttgat tgccaagaaa gagtttcctg atgaagaata
     9481 tggattctat taccctcaat tgacttttca taaggttgct gtgactgaaa aatatcttcc
     9541 agctactata gaagtcttgt catcaccttt catggttatc aaacatggtg ctgtttataa
     9601 atttaacaga gctaaaggta tt
//
LOCUS       DAJVBX010000179         9547 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.179, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000179 DAJVBX010000000
VERSION     DAJVBX010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 9547)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9547)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9547
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.179"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            110..1075
                     /gene="dusB"
                     /locus_tag="OPV72_003632"
     CDS             110..1075
                     /gene="dusB"
                     /locus_tag="OPV72_003632"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008785970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HCR9915828.1"
                     /translation="MRIGQYQLRNRLIAAPMAGITDRPFRTLCYEMGAGLTVSEMMSS
                     NPQVWESDKSRLRMVHVDEPGIRTVQIAGSDPVEMADAARINVESGAQIIDINMGCPA
                     KKVNRKLAGSALLQYPDLVKSILIGVVNAVDVPVTLKIRTGWAPEHRNCVEIAQLAED
                     CGIQALTIHGRTRACLFNGEAEYDSIRAVKQKVSIPIIANGDITNPHKARAVLDYTGA
                     DALMIGRAAQGRPWIFREIQHYLDTGELLPPLPLAEVKRLLCTHVRELHDFYGQAKGY
                     RIARKHVSWYLQEHAPDDQFRRTFNAIEDASEQLEALEAYFENFA"
     gene            1101..1397
                     /gene="fis"
                     /locus_tag="OPV72_003633"
     CDS             1101..1397
                     /gene="fis"
                     /locus_tag="OPV72_003633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001465625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator Fis"
                     /protein_id="HCR9915829.1"
                     /translation="MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNG
                     QDVNDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN"
     gene            1483..2367
                     /gene="yhdJ"
                     /locus_tag="OPV72_003634"
     CDS             1483..2367
                     /gene="yhdJ"
                     /locus_tag="OPV72_003634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine-specific DNA-methyltransferase"
                     /protein_id="HCR9915830.1"
                     /translation="MKAECEPQYFGDESKKIIHGDALTELKKLPSESIDLIFADPPYN
                     IGKDFDGMVESWDEASFLAWLYECIDECHRVLKKHGTMYIMNSTENMPYIDLKCRTLF
                     TIKSRIVWSYDSSGVQAKKYFGSMYEPILMMVKNPKSYTFNRDAILVETTTGAKRALI
                     DYRKNPPQPYNQKKVPGNVWSFPRVRYLMDEYENHPTQKPSALLKRIILASSNPSDTV
                     LDPFAGSFTTGAVAAASGRKFIGIELNNEYVKMGLRRLSVTSHYSENELAKVKKRKTQ
                     NLSKKQRNVGINALSSEK"
     gene            2450..2614
                     /locus_tag="OPV72_003635"
     CDS             2450..2614
                     /locus_tag="OPV72_003635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2556 family protein"
                     /protein_id="HCR9915831.1"
                     /translation="MIRKYWWLVVFAVSVFLFDALLMQWIELMATEQDKCRNMDSVNP
                     LKLINCTDLE"
     gene            2765..4339
                     /locus_tag="OPV72_003636"
                     /pseudo
     CDS             2765..4339
                     /locus_tag="OPV72_003636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462298.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
     gene            4341..4766
                     /locus_tag="OPV72_003637"
                     /pseudo
     CDS             4341..4766
                     /locus_tag="OPV72_003637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462300.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
     gene            4778..7892
                     /locus_tag="OPV72_003638"
                     /pseudo
     CDS             4778..7892
                     /locus_tag="OPV72_003638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462301.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
     gene            8129..8350
                     /locus_tag="OPV72_003639"
     CDS             8129..8350
                     /locus_tag="OPV72_003639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915832.1"
                     /translation="MKRLIPVALLTTLLAGCAHDSPCVPVYDDQGRLVHTNTCMKGTT
                     QDNWETAGAIAGGAAAVAGLTMGIIALSK"
     gene            complement(9178..9293)
                     /gene="rrf"
                     /locus_tag="OPV72_003640"
     rRNA            complement(9178..9293)
                     /gene="rrf"
                     /locus_tag="OPV72_003640"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(9333..9408)
                     /locus_tag="OPV72_003641"
     tRNA            complement(9333..9408)
                     /locus_tag="OPV72_003641"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9373..9375),aa:Thr,seq:ggt)
BASE COUNT         2367 a         2355 c         2439 g         2386 t
ORIGIN      
        1 gattcattga tctacaacag tggattgttc aaagtttggc ctttcatctc gtgcaaaaaa
       61 tgcgtaatat acgccgcctt gcagtcacag tatggtcatt tcttaactca tgcgcatcgg
      121 acaatatcag ctcagaaatc gcctgatcgc agcgcccatg gctggcatta ctgacagacc
      181 tttccggacg ctgtgctatg agatgggagc aggattgaca gtatccgaga tgatgtcttc
      241 taacccgcaa gtgtgggaaa gcgataaatc tcgtttacgg atggtgcacg ttgatgagcc
      301 aggaattcgc acggtgcaaa ttgccggtag cgaccctgtt gagatggccg atgccgcacg
      361 tattaacgtg gaaagcggcg cccagattat tgatatcaat atggggtgcc cggcgaagaa
      421 agtgaatcgt aagctggcag gttcagccct cttgcagtac ccggatttag tgaagtctat
      481 actcatcggg gtcgtaaacg cggtggacgt tcctgtgact ctcaagattc gcaccggctg
      541 ggcgccggaa caccgtaact gcgtagagat tgcccaactg gctgaagatt gtggtattca
      601 ggccctgacc atccatggcc gcacccgcgc ctgtttgttc aacggagaag ctgaatacga
      661 cagtattcgg gcagttaagc agaaagtttc cattccgatt atcgcgaatg gcgacattac
      721 taacccgcat aaagccagag ctgttctcga ctatacaggg gcggatgccc tgatgatagg
      781 ccgcgcagct cagggaagac cctggatctt tcgggaaatc cagcattatc tggacactgg
      841 ggagctgctt ccgccgctgc cgctggcaga ggtaaagcgc ttgctttgca cgcatgttcg
      901 ggaactgcat gacttttacg gtcaggcaaa agggtaccga atcgcgcgta aacacgtctc
      961 ctggtatctc caggaacacg ctccagacga ccagtttcgg cgcacattca acgctattga
     1021 ggacgccagc gaacagctgg aggcgttgga ggcatacttc gaaaattttg cgtaaacaga
     1081 aataaagagc tgacagaact atgttcgaac aacgcgtaaa ttctgacgta ctgaccgttt
     1141 ctaccgttaa ctctcaggat caggtaaccc aaaaacccct gcgtgactcg gttaaacagg
     1201 cactgaagaa ctattttgct caactgaatg gtcaggacgt taatgacctg tatgagctgg
     1261 tactggctga agtagaacag cccctgttgg acatggtgat gcaatacacc cgtggtaacc
     1321 agacccgtgc tgctctgatg atgggcatca accgtggtac gctgcgtaaa aaattaaaaa
     1381 aatacggcat gaactaattt cgattagcta actgcttgtt taaaaaggcg ctactcggca
     1441 tggggaagcg ccttttttat acgcattaca tggaatttgg tcatgaaagc ggaatgtgaa
     1501 cctcagtact ttggcgatga atcgaagaag attattcacg gtgacgcgct aacagaactt
     1561 aaaaaactgc cttctgaaag cattgactta atttttgccg atccgcctta caatatcgga
     1621 aaagatttcg acggtatggt ggaatcctgg gacgaagcgt cttttctggc ctggctgtat
     1681 gaatgcattg acgagtgcca ccgcgtactg aagaaacacg gcaccatgta catcatgaat
     1741 agcacagaaa atatgccgta tatcgatctc aaatgccgaa cgctttttac catcaaaagc
     1801 cgtatcgtct ggtcctatga tagttccggg gtgcaggcga aaaaatactt tggttctatg
     1861 tatgaaccga tcctgatgat ggtaaaaaac ccgaaaagct atacctttaa ccgtgacgcg
     1921 attctggtcg agaccactac gggcgctaag cgcgcgctaa tcgattatcg aaaaaacccg
     1981 ccccaaccat acaatcagaa aaaagtgccg ggcaacgtct ggtcatttcc tcgcgtacgt
     2041 tatctgatgg atgaatatga aaaccatcct acgcaaaagc ccagcgcgct gttaaaacgg
     2101 atcatactgg cctcttctaa cccgagcgat accgtattgg accctttcgc gggcagtttc
     2161 accacaggcg ctgtcgcagc ggcgtcaggt cgtaagttta tcggtattga actcaataat
     2221 gagtacgtaa aaatggggct cagaagattg agcgtcactt cgcattattc agaaaatgaa
     2281 cttgcaaaag tcaaaaagag aaaaacacaa aacctgtcca aaaagcagcg aaatgtcggg
     2341 ataaacgcgc tatcttcaga gaagtaaaag cattgtaagt ccgcttttca gcgtcaaaat
     2401 ttcatgtata ttcccagcac gcatgggcat gaatacacag gatttgacga tgatacgtaa
     2461 gtattggtgg ctggttgttt ttgccgtctc cgtttttctt tttgatgcgc ttttgatgca
     2521 atggatcgaa ttgatggcga ctgaacagga taagtgccga aacatggatt cggttaaccc
     2581 tcttaaattg atcaattgta ccgatctgga gtagcgaatc gggcgattta acctatgatt
     2641 atttatcacc cggatttctt ttatccctta taaaaacagg gaattaaaac acgttgagga
     2701 taaaagaagg ggtgatactg tctcgtcctg ttcttttcct gcataaccaa tgagctaatg
     2761 atacatgccg gttagtgagt acaaccacat ccttgtggcg gtttcatttg ctgtcgctat
     2821 ttttgcgtcc tataccgcat taaatatggc cggacgcgta gccggaagcg cccgatcaaa
     2881 cgccagaata tggctaatgg gcggcggctt cgcgctgggc gtcggtattt gggagatgca
     2941 ttttgtcggg atgctggcga tggatcacgc gatgaacatg cgcttcgatc cgttcctcac
     3001 cggcctctcc atgctgatcg cgatcggctc ctccctgttt gcgctatggc tggttagcgc
     3061 tgaaaaactg cgcctgcgcc gtttactgcc gggcgcgctg gtgatgggac tgggcatcag
     3121 cgcaatgcat tataccggga tggcggcgct gcaatttgct tccattatcg tttggaatag
     3181 cgcgtgggtt gccctctcta tcattatcgc gctactggcg tcctgcggcg cgctgtggct
     3241 cacgttccgc ctgcgtaatg agggaacaga tgtcgccctg aggcgagcag gcgccgcggt
     3301 attaatgggg atagctatcg ccggcatgca ttacgccggc atgaaggccg cacactttcc
     3361 ccaaaactgg ccgatggaac atcgtggcgt cgatagcaac tggctggctg ttcttgtcag
     3421 cgtggtcgcg ctgactatcc tgggtattac tctgctggtt tctttatttg acgcccggct
     3481 tcaggcccgt accgcactac ttgcctcttc gctggcgcag gcgaaccagg aactggcgca
     3541 gttggcgctg catgatacgc tcacccgttt accaaaccgg gtactccttg aggatcgtct
     3601 ggaacaggcc atcagcaaag cgaatcggga aagcacgtct ttcgcgctac tgtttatgga
     3661 tctggatggc tttaaagccg ttaatgacgc ttatggtcat gatattggcg ataagctact
     3721 ggtggcggtc acgcatcgtc tgaaccaacc gctgagcggg cagtttaccc tggcgcggat
     3781 tggcggcgac gaatttgtgc tgcttgcgga agtcagcgcg cctgacgaag cggcttccct
     3841 tgccagcgcg ctggtacatt cgatagatgc gccctttacg atagatccgt acgaactggt
     3901 tgtcaccctt agcgtgggaa tagcgctcta tccgctggac ggaaaaaacg aacgggaact
     3961 gatgttcaac gccgatgccg cgatgtacca cacgaagcat acggggcgta acggatacca
     4021 tttctttcag ccatcaatga atatgctggc gcaaacccaa cttcagctaa tgaatgacct
     4081 gtggctggcg ctggaaagac aagagctcag gctggtgtat cagcctaaat ttcaggctcc
     4141 tgccggcccc attgtaggat ttgaggccct gttgcgctgg tatcatccaa aacaaggcgt
     4201 actgaatcct gaccagtttt taccgctggc ggaaaaaacg ggtcttatcg tcactatcgg
     4261 tagctgggtg atagacgagg cgtgtcgaca gctccgcgag tggcacttac agggatacgc
     4321 cttatggtca gtggcggtaa ctggtaatgg aaaatggtca ggtctacccg attaaaggca
     4381 cgctgcaatt ttccgacgtt accgtagatg aaagcaccgg ctctatcacg ctcagggcgg
     4441 tgttccctaa cccgcaacac agtctgcttc ccggtatgtt tgttcgcgcc cgcatcgatg
     4501 aaggcgtcca gcccaatgcc atccttgtcc cccagcaggg cgtgacccgc acgccgcgcg
     4561 gcgacgcaat ggtgatggtg gttaacgata aaagtcaggt cgaagcccgc aatgtcgtgg
     4621 cgacgcaggc tattggcgat aaatggctca tcagcgaagg gttaaaaccg ggcgataagg
     4681 tcatcgtcag cggcttacaa aaagcgcgac cgggcgtcca ggtgaaagcc actaccgatg
     4741 ctcctgcagc gaaaacggcg caataaggta accgtacatg gcaaactttt ttattagacg
     4801 tcctattttc gcctgggttc tggccattat cctgatgatg gctggcgcac tggcaataat
     4861 gcaacttccc gttgcgcagt atccaaccat tgcgccgcca gcggtttcta tttctgcaac
     4921 ctatcctggc gcggatgcgc agacggtaca ggatacggtt actcaggtta tcgaacaaaa
     4981 tatgaacggt atcgataacc tgatgtatat gtcctctacc agcgactctg ctggtagcgt
     5041 gaccatcact ctgaccttcc agtccggaac cgatccggat atcgcgcagg ttcaggtgca
     5101 aaataaattg cagctcgcca cgcctttact gccgcaagaa gtccagcagc aggggattag
     5161 cgttgaaaaa tccagcagca gctttttgat ggtcgccggg ttcgtctcgg ataatccgaa
     5221 cactacccag gacgacatct ctgactatgt cgcctctaac attaaggatt ctatcagccg
     5281 tctgaacggc gtgggcgacg ttcagctatt tggcgcacag tacgccatgc gtatctggct
     5341 ggatgcgaat ctgctaaata aataccagct cacgccagtt gacgtcatca accagttaaa
     5401 agtacagaac gaccagattg cggcaggcca actgggcggt acgccagcat taccgggcca
     5461 gcagcttaac gcctcaatca tcgcccaaac gcgtctgaaa gatccggaag agttcggcaa
     5521 agttacgttg cgcgtcaata ccgacggctc tgtcgtccat ctcaaagatg tcgcgcgtat
     5581 tgagcttggc ggtgaaaact ataacgttgt agcgcgcatt aacggtaaac cggcctccgg
     5641 tctcggtatt aaactggcga ccggcgctaa cgcgctggat accgcaaccg caatcaaagc
     5701 gaaactggcg gaactgcagc ctttcttccc tcagggaatg aaggtggttt atccttatga
     5761 cactacgccc ttcgtaaaaa tatctatcca cgaagtggta aaaacgctat ttgaagcgat
     5821 tattctggtg ttcctggtaa tgtatctgtt cttacagaat atccgggcaa ccctgattcc
     5881 taccatcgct gttcctgtcg tgttgctagg cacttttgcg gtactcgccg cctttggcta
     5941 ttccatcaat accctgacga tgttcggcat ggtactggcg atagggctgc tggttgacgg
     6001 tgcgatagtg gtcgtagaaa acgttgaacg tgtaatgatg gaggataacc tttctcccag
     6061 agaggcgacg gaaaaatcca tgtcgcagat ccagggagcg ctggtcggta tcgcgatggt
     6121 actgtctgcg gtatttatcc cgatggcctt ttttggcggc tcgaccgggg caatttatcg
     6181 ccagttctct attactattg tttcagcaat ggcgctatcc gttctggttg cgttgattct
     6241 gacgccagcg ctatgcgcta cgctgcttaa acccgtatct gctgaacatc acgagaaaaa
     6301 aagcggcttc tttggctggt tcaataccag gtttgaccac agcgttaacc actatactaa
     6361 cagcgtaagc ggtatcgtgc gtaatacggg tcgctatctc attatctatc tacttattgt
     6421 agtcggaatg gcggttctgt ttttacgcct cccgacctcc ttcctgccgg aagaagatca
     6481 gggggtattc ctgactatga ttcagctccc ctctggcgct acgcaagaac gtacgcagaa
     6541 agtgctggat caagtcactc attactacct gaataatgaa aaagcgaacg tcgaaagcgt
     6601 gtttaccgta aacggcttta gctttagcgg tcagggacaa aactcaggga tggcatttgt
     6661 cagccttaaa ccctgggaag agcgtaacgg tgaagaaaat agcgtcgaag ccgttatcgc
     6721 cagagcgaca cgcgccttta gccagattcg cgacgggttg gtgttcccct tcaacatgcc
     6781 ggcaattgtc gagttaggta ccgcgacagg tttcgacttc gaactgattg atcagggagg
     6841 actcggtcat gatgcgttaa caaaagcgcg taatcaactc ctgggtatgg tcgcgaagca
     6901 tcctgatcta ttagtgcgcg tacgcccgaa cgggctggaa gacacgccac agttcaagct
     6961 ggatgtcgat caagaaaaag cacaggcgct cggcgtttcg ctgtctgata tcaacgaaac
     7021 catctccgcg gcgttgggcg gctattacgt taacgacttt atcgatcgcg gacgagtgaa
     7081 aaaagtatac gttcaggctg acgctcagtt ccgtatgctg ccggaagata tcaacaatct
     7141 ttatgtacgc agcgccaatg gcgagatggt gcccttctct acctttagct cagcacggtg
     7201 gatttatggt tcgccacgcc tggaacgcta taacgggatg ccgtcaatgg aactgctcgg
     7261 tgaagcagcg cccggacgaa gtaccggtga agccatgtcg ttaatggaaa acctggcttc
     7321 acagctgcca aacggtattg gctatgactg gacaggtatg tcgtatcagg aacggttgtc
     7381 aggtaaccag gcgccggcgc tgtacgcaat ctcactcatt gtcgttttcc tctgccttgc
     7441 cgctctgtat gaaagctggt caattccgtt ctcggtaatg ctggtcgtac cgctccggcg
     7501 tggttggcgc tctgcttgca gcgtcattgc gcggcctgaa taatgacgtt tacttccagg
     7561 ttggcttgtt aaccactatt ggcctttctg ctaaaaacgc catcctgatt gttgagttcg
     7621 ccaaagatct catggaaaaa gaaggacgtg gattgattga agcgacgctg gaagcatccc
     7681 gtatgcgttt acgtcctatt ctaatgacct cgctggcctt tattctcggg gtaatgccgt
     7741 tagttatcag tcgtggcgca ggtagtgggg cacagaacgc agtaggcaca ggggttatgg
     7801 ggggaatgtt aaccgcaacc ttattagcta tcttcttcgt gccagtattc ttcgttgttg
     7861 taaaacgccg atttaatcgc catcatgatt aaccagtaaa cagaggcgtc ttcggacgcc
     7921 ttttaaacgg tacgtcttta tctccgctat tcccccctct ccgcttacct ctgcattctc
     7981 catagttttt acaattcaca tgaattgaga tgattcctca tgtcagccat tttttctgtg
     8041 gtggtaaaat aactctcgtt ttcacagcgg ttagagccag catttacgtt gctgtacttt
     8101 gcgaaacgct gattaatgag gtaacaccat gaaaagacta attccagttg cattgcttac
     8161 caccttattg gcaggttgtg cacatgattc tccctgcgta ccggtttatg acgatcaagg
     8221 gcggctggtt cataccaata catgtatgaa aggtacaacg caggataact gggagacagc
     8281 aggcgctatc gctggcggcg ctgcggcggt agcagggttg acgatgggta tcattgcgct
     8341 ttctaaatga tacatgcagg cgcggcaatg ccgcgctttc agtaataata taaaggtcgt
     8401 aaggatactc agcgacgtaa tctattcagc ctatccccga aagttaacac gataaaacgc
     8461 tctcttttct tactcgccca tcccgatggt atttattcta ttccttgtcc gatgcagaca
     8521 aaattgtagc ttgatagcat cgtaagccgc attacaaaca ggctttatac agtaagactt
     8581 agagcgtggt cattaggcgt aattattaca gacagtctgg atataaaccg gaacatacac
     8641 gtaatacatg aggattttga gcactgtccc agggccaaac tggcaaataa aatagcctaa
     8701 tgggccagat tcttagtcct cagcgaatat ctctattgct tattagaggc gtaagtaaaa
     8761 gccgtttgta catctacttc agcacggttc acattcgatg gttcaggcgg atatatggcg
     8821 ggaaatcacg tttactaaaa cggtttttat ccactctacg aagatgttat atacccaaaa
     8881 taattcgagt tgcttaaagg cggcaaggga gtgagtcccc aggagcatag ataactatgt
     8941 gactggggtg agcgacaaat ctgccgggag cagatttaaa cgtcgcgtgc gacggcccgt
     9001 cagggcgagg cccatgaatg ggccgagtaa tccgtagcca acacataagc gacttgaagt
     9061 atgaaaggta taaaccaaat ataaaacgcg tcggcgtcat tatccgataa ctttttccat
     9121 agagagataa atgcaaaaag gcccaatctt tcgattgggc cttttgcttt atttgatgtc
     9181 tggcagttcc ctactctcgc atggggagac cccacactac catcggcgct acggcgtttc
     9241 acttctgagt tcggcatggg gtcaggtggg accaccgcgc tactgccgcc agacaaattc
     9301 tttttcaaat gccgaacttt aaccgtatta agtggtgctg atacccagag tcgaactggg
     9361 gacctcaccc ttaccaaggg tgcgctctac caactgagcc atatcagcac actaaatttg
     9421 atgcctggca gtttatgaat cacttcgtga ttcacccttc gggccgttgc ttcgcaacgt
     9481 tcaaaagatt cgcttttgtc ctactctctg tcgagtagtg aactgccccg aaagttaatg
     9541 ccatact
//
LOCUS       DAJVBX010000180         9472 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.180, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000180 DAJVBX010000000
VERSION     DAJVBX010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 9472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9472
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.180"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            35..1150
                     /gene="iroB"
                     /locus_tag="OPV72_003642"
     CDS             35..1150
                     /gene="iroB"
                     /locus_tag="OPV72_003642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="salmochelin biosynthesis C-glycosyltransferase
                     IroB"
                     /protein_id="HCR9915833.1"
                     /translation="MRILFVGPPLYGLLYPVLSLAQAFRVNGHEVLIASGGKFAQKAA
                     EAGLVVFDAAPGFDSEAGYRRQEALRKENNIGTKMGNFSFFSEEMTDPLVAFAGQWRP
                     DLIVYPPLGVVGPLIAAKYDIPVVMQTVGFGHTPWHIKGVTKSLSNAYRRHGVSAPPR
                     DLAWIDVTPPSMSILQNDGEPVISMQYVPYNGGAVWEEWWERTPDRKRLLVSLGTVKP
                     MVDGLDLISWVMDSASEVDAEIILHLPANARSDLRSLPPNVRLVDWLPMGIFLNGADG
                     FIHHGGAGNTLTALHAGIPQIVFGQGADRPVNARAVVERGCGIIPGKSGLTSSMINTF
                     LGNRALRETSQEVAAEMAAQPCPTEVAKKLIAMLQHG"
     gene            1231..4887
                     /gene="iroC"
                     /locus_tag="OPV72_003643"
     CDS             1231..4887
                     /gene="iroC"
                     /locus_tag="OPV72_003643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="salmochelin/enterobactin export ABC transporter
                     IroC"
                     /protein_id="HCR9915834.1"
                     /translation="MPATHSPMPARAWIVRLARVCWERKTLSIIVIVASVSTILLAAL
                     TPLITRQAVNDAIAGDTTRLPLLACGLLLIALFDFIGNYVRRGYAGELSLWVQHTLRS
                     RAFDSIQKLDGAGQDALRTGQVISRTNSDLQQVHTLLQMCPVPLAVLTYYVAGIAVML
                     WMSPSMTLIVICVLAALAITALRARRRVFAQTGLASDRLAHMTEHMREVLEQISVVKS
                     CVAELRETRWLDGQSRQMVRVRIGAAISQAMPGATMLALPVIGQIVLLCYGGWSVMNG
                     RIDLGTFVAFASFLAMLTGPTRVLASFLVIAQRTQASVERVFALIDTRSRMEDGTESV
                     EGQIIGLDVEKMSFHYDNGNRILNEISFSIHAGETVAVVGASGSGKSTLLMLLARFYD
                     PTSGGVWLNTTTGQQNIRDLKLTALRRRVGVVFEDAFLFAGTVAENIAYGHPQATQDD
                     IRRAADAAGASGFINALPQGFNTRLTERGSNLSGGQRQRIALARALITAPELLILDDT
                     TSAVDAGTEAEINTALGRYADNEHMLLVIARRRSTLQLVDRIVVLDKGRVVDIGTQAE
                     LDARCPTFRSLMSGEGDFLALAPAEQRTLWPTTQAVKSDDAHERQTTAGKGFVDRMTR
                     VPERAVQMALAGHGSQVSSLLTPVAWMFVIAALLIALDSAAGVGVLVLLQRGIDSGVA
                     AGDMSTIGICALLALCLVAIGWCCYALQTIFAARAAESVQHTVRLRSFSHLLRLSLPW
                     HEKHIDSRLTRMTVDVDSLARFLQNGLASAATSIVTMVAIAAAMFWLDPILALTALSA
                     VPVVILATWIYRRLSSPAYAQARLEIGKVNSTLQEKVSGMRVVQSHGQQKQEAARLRA
                     LSDNFRATRVRAQKYLAVYFPFLTFCTEAAYAAVLLIGATRVAEGEMTPGILAAFFLL
                     LGQFYGPVQQLSGIVDSWQQATASGKHINALLATEETENIEPSSITPGTGGALRLEAL
                     TFRYPEKTQPVLDNLSLTIPPGTVVAVVGRSGAGKSTLIKLLAGLYSPGSGQIRVGER
                     LIDAASLSDYRRQTGLVTQDVALFSGDIAENIRYSRPDSSDTEVEIAARQAGLFETVQ
                     HLPLGFRTPVNNGGTDLSAGQRQLIALARAQLAQAHILLLDEATARIDRSAEERLITS
                     LTGVTHTEKRIALIVAHRLTTARRCDVIVVIDKGCIAEYGSHEQLIAAHGLYARLWRA
                     SVGQTRDTQGEVVG"
     gene            4997..6241
                     /locus_tag="OPV72_003644"
     CDS             4997..6241
                     /locus_tag="OPV72_003644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HCR9915835.1"
                     /translation="MRLSPPVAPVAIQTATRLRRQLAAGSQVDASHFWREANSLALPL
                     VTAINGADDEREVTFLWRAASPLRGVYVRLNRVTDKDNVAKGMMTQLPTTDIWHLTLR
                     LPASYCGSYTMVEIPPKTPDETVLQLGSRFASLVGKADPLNSTPGINVRGNAQESVLA
                     LDHAPAQEEWSGCRAYAGQLFTSEHRLAGQRRRVRLYLPDVPVEQPLGLLVLTDGEIW
                     FDHLGVSAAIDAAIRSGRIAPVAVLGVDNINARERVAILGGRRELVLDIAERLLPTLR
                     AKYPERQWADRTQTVLAGQSLGGVTALMAARHAPESFGLVLSHSPSMWWTPDNRNRPP
                     HFSAEERSWVSEHVLSAPSPAVRTHLCVGSLEGSTVPQVKQLHEKLRAAGVESHCCVY
                     TGGHDYAWWRGALIDGLRLLPR"
     gene            6273..7190
                     /locus_tag="OPV72_003645"
     CDS             6273..7190
                     /locus_tag="OPV72_003645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCR9915836.1"
                     /translation="MYGRQYHNKCYRVALFLVSFCFSALSYAQPDMQPLGPNMADKGS
                     GYYHFRVNDFQSADGARHYRVWTAIPNKAAPPSGYPVLYMLDGNAVMDRLPETLLKQL
                     ADHSPPVIVAIGYQTNLPFDLNGRAYDYTPAPGIDRDDSENNPRFHRKTGGGPAFRQL
                     LERHIAPQVEQGITINPERRGIWGHSYGGLFVLDSWLSSSFFHIYYSASPSLSRDNFA
                     LLNRLTAVKPSPFCHKKLIIMEGSASNGDSRQRQMAELLQKVQETVRTLENNGVNAAL
                     QHYPGLGHGPMFNASFRSALLGISREPAS"
     gene            complement(7250..9430)
                     /locus_tag="OPV72_003646"
     CDS             complement(7250..9430)
                     /locus_tag="OPV72_003646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461704.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent siderophore receptor"
                     /protein_id="HCR9915837.1"
                     /translation="MGMRVKKFIWLITVVSTGINSPLSAAESTDDNGETIVVESTAEQ
                     VLKQQPGVSIITRDDIQKNPPVNDLADIIRKMPGVNLTSNSASGTRGNNRQIDIRGMG
                     PENTLVLIDGVPVTSRNSVRYSWRGERDTRGDTNWVPPEMVERIEMIRGPAAARYGSG
                     AAGGVVNIITKRPTNDWHGSLSLYTNYPESSKEGDTRRGNFSLSGPLAGDTLTMRLYG
                     NLNRTDADSWDINSSAGTKNAAGREGVTNKDINSVFSWKMTPQQILDFEAGYSRQGNI
                     YAGDTQNSNSNAVTKSLAQSGRETNRLYRQNYGLTHNGIWGWGQSRLGFYYEKTDNTR
                     MNEGLSGGGEGRITNDQTFTTNRLTSYRTSGEVNVPVIWLFEQTLTVGAEWNRDELND
                     PSSTSLTVKDSNIAGIPGSAANRSSKNKSEISALYVEDNIEPMAGTNIIPGLRFDYLS
                     ESGSNFSPSLNLSQELGEFVKVKAGIARAFKAPNLYQTSEGYLLYSKGNGCPKDITSG
                     GCYLVGNKNLDPEISINKEIGLEFTVDDYHASVTYFRNDYQNKIVAGDQIIGRSASGA
                     YVLQWQNGGKALIEGIEASMAVPLMPDRLNWNTNATYMITSEQKDTGNPLSIIPKYTV
                     NTFLDWTITNALSANVNWTLYGKQKPRTHAESRSEETKGLSGKALGAYSLVGANVNYD
                     INKNLRLNVGISNIFDKQIYRSAEGANTYNEPGRAYYAGVTASF"
BASE COUNT         1993 a         2679 c         2646 g         2154 t
ORIGIN      
        1 attcgattta tgacgtggag agagaggatt tctcatgcgt attctgtttg tcggtccacc
       61 actgtatgga ctgctatacc ctgtgctgtc cctggcgcaa gcgtttcgtg ttaatggcca
      121 tgaagtgctg attgcaagcg gtggaaaatt tgcacagaaa gcagcagaag ctgggttggt
      181 ggtatttgac gctgcgcctg gtttcgattc ggaagcgggt tatcgccgtc aggaggcatt
      241 gcgaaaagaa aataacattg gaacaaaaat ggggaacttc tcatttttca gcgaagagat
      301 gaccgacccg ctggtcgcgt tcgccggaca gtggcggcca gatctcatcg tctatcctcc
      361 ccttggggtc gttggaccac tgattgccgc taagtatgac attccggtag taatgcaaac
      421 cgtcggcttc ggtcatacgc cctggcacat caaaggcgtg acgaaatcac tttctaacgc
      481 ctaccgccgc catggggtca gcgcgccacc aagagatctg gcgtggatag acgtcacacc
      541 gcccagcatg agcatactgc aaaatgacgg agagccggtt atctccatgc aatacgtccc
      601 gtataacggc ggcgccgtct gggaagaatg gtgggaacgt acacctgatc gcaagcgtct
      661 tctggttagc ctcggcaccg tcaaaccgat ggtggatggc ctggatctga tttcctgggt
      721 aatggattct gccagcgaag tagatgccga aatcattctg catcttccgg caaacgcccg
      781 ctcggattta cgttctctgc cgccgaatgt ccgtctggtc gactggcttc cgatgggcat
      841 tttccttaac ggcgccgacg gttttatcca ccatggcggc gcaggcaaca ctctgacggc
      901 gctgcatgcc ggcattccgc agatagtctt tggccagggt gccgacagac ctgtcaatgc
      961 ccgcgccgtg gtcgagcgcg gatgcggcat tattcccggt aagagcggac ttacgagcag
     1021 catgatcaat acctttctcg gtaatcgcgc gcttcgcgag acgtcgcagg aagtcgcggc
     1081 ggaaatggcg gcccagcctt gcccgaccga ggtggcaaaa aaactgatcg ccatgctgca
     1141 acacggctaa ccgcggcagc gcaatgacaa tatggcggct gagcccagac tgtgtcgcca
     1201 taactcatct ttcaccgata aggaggctta atgcccgcga ctcattcccc catgcccgct
     1261 cgtgcctgga tagttcgcct tgcccgcgtg tgttgggaac gtaaaacact gagcatcatt
     1321 gtcatcgtag catcagtatc gaccatttta ctggctgcgc tgacgccgct aataacgcgt
     1381 caggccgtca atgacgcgat agcaggcgat acgacccgcc tgccgttact tgcctgcggc
     1441 ctgctgttaa ttgccctttt tgattttatc gggaattacg tgcgccgcgg ctatgccgga
     1501 gaactctcgt tgtgggttca gcatacgtta cgtagccgtg cgttcgacag tattcaaaaa
     1561 ctggacggcg caggccagga cgccttgcgt accgggcagg tcatttcgcg taccaacagc
     1621 gatcttcaac aggtacacac cttgctacag atgtgtccgg tgccgctggc ggtgctcact
     1681 tactatgtgg ccggtatcgc ggtgatgcta tggatgtcgc catccatgac gcttatcgtg
     1741 atttgcgtac tggccgccct tgctattacc gccctgcgcg cccgtcgccg tgttttcgcg
     1801 caaacggggc ttgcctcaga ccggctggcg cacatgacgg aacatatgcg cgaagtattg
     1861 gaacagatct cagtggtgaa gtcctgcgtg gcggagttac gcgaaacgcg ttggctcgat
     1921 ggtcagtcgc ggcagatggt gcgggtacgg atcggtgccg ctatctcgca ggcgatgccg
     1981 ggcgcaacca tgctggcgct accggtgata gggcagatcg tcctgctgtg ctatggcggc
     2041 tggtcggtga tgaacgggcg catcgatctg ggaaccttcg tagcgttcgc gagttttctc
     2101 gctatgttga ccggccctac ccgcgtactg gcatcgtttt tggttatcgc acagcgcaca
     2161 caggcgtcgg tagagcgcgt cttcgcgctt atcgacacgc gttctcgcat ggaagacggt
     2221 actgagtcgg ttgagggtca gattatcggg ctggacgtgg agaagatgag tttccactac
     2281 gacaacggta accgtatcct caatgagatc tcgttttcca ttcacgccgg tgaaaccgtg
     2341 gcggtggttg gcgcatccgg ctccgggaaa tcaacattgc tgatgttgct ggcgcgcttt
     2401 tacgatccca cctccggcgg agtatggctc aacaccacta cgggtcaaca gaatattcgc
     2461 gacctgaaac tgacggcgct tcgtcgtcgc gttggcgtag tttttgaaga cgcgtttctg
     2521 tttgccggta cggtggcgga aaacatcgcc tatgggcacc cgcaagcgac tcaggacgac
     2581 attcgacgcg ccgccgatgc cgcaggcgcc agcgggttca tcaatgcgct accgcagggg
     2641 ttcaacaccc gactgaccga acgcggaagc aacctctccg gcggccaacg ccagcgtatt
     2701 gcgctagccc gggcactgat taccgcgccg gaactgctga ttctcgatga caccacctcg
     2761 gcggtcgatg ccggtactga agcggaaatt aacacggctc ttggtcgtta tgccgataat
     2821 gagcatatgc tgctggtgat tgcacgccgc cgttcaacac tgcagttagt cgatcggatc
     2881 gtcgtgctgg ataaaggccg cgtcgtggat atcggtaccc aggcggagct ggatgcaagg
     2941 tgtccgacgt ttcgctcgct gatgagcggc gagggggatt ttctcgccct tgccccggca
     3001 gaacaacgta cgctatggcc aacaacgcag gcggtaaaat ccgacgacgc gcatgagcgc
     3061 cagacaaccg ccggaaaagg ttttgtcgac cggatgacgc gcgttccgga acgcgccgta
     3121 cagatggcgc tggcaggcca cgggagtcaa gtctcatcgc tgctgacgcc agtagcctgg
     3181 atgttcgtca tcgccgccct gcttatcgcg cttgattccg ccgcaggcgt tggcgtgctg
     3241 gtgcttttgc agcgcggtat tgactcaggc gttgccgcag gggatatgtc gactattggc
     3301 atatgcgccc tgctcgcgct gtgcctggtg gcgatcggtt ggtgctgcta tgcgctgcaa
     3361 acgatcttcg ccgcccgcgc ggcagagtcg gtacagcata cggtacgctt acgcagcttc
     3421 agccacctgc tacgcctgag tcttccctgg cacgagaagc acatcgactc gcgtcttact
     3481 cgcatgaccg tcgacgttga ttcactcgcc cgatttctgc aaaacggtct tgccagcgcg
     3541 gccaccagca tcgtgacgat ggtcgctatc gccgcggcaa tgttctggct tgaccccatt
     3601 cttgcgttaa cggcattaag cgccgtacct gtagtgatac tggcgacgtg gatttaccgc
     3661 cgtttgagct cgcctgctta cgcccaggca cggctggaaa ttggtaaggt gaacagtacg
     3721 cttcaggaaa aggtctccgg tatgcgggta gtgcagtcac acggtcaaca gaagcaggaa
     3781 gccgccaggc tacgggcgtt atcagacaac ttccgcgcca cccgcgtgcg ggcgcaaaaa
     3841 taccttgctg tctattttcc gttcctgacc ttctgcaccg aggctgccta tgccgccgtg
     3901 cttttaatcg gagcgacccg ggtcgccgaa ggcgaaatga cgcccgggat actggcggcg
     3961 ttcttcctgc tattgggaca attttatggc ccggtacagc agttgtcagg cattgttgat
     4021 tcctggcagc aggcgaccgc cagcggcaaa catatcaatg cgctattggc gactgaggaa
     4081 acggagaata ttgaaccgtc ctccataacg cctggcactg gcggcgcgct acgtctggag
     4141 gcattgacat tccgctatcc cgaaaaaacg caacctgtgc ttgataatct ctcgctcacc
     4201 attccgccag gaacggtagt cgcggtggtc ggacgtagcg gcgccggcaa atcgacgctg
     4261 atcaagctgc tggccgggct ctactctccc ggcagcgggc aaatccgtgt cggtgagcgc
     4321 ctaattgatg ccgcgtcgct tagtgattat cgtcgccaga cggggctggt cacccaggat
     4381 gtcgcattat ttagcggcga tattgccgaa aatatccgct attcgcggcc agacagcagc
     4441 gacacggagg tggagatcgc ggcgcgacag gcgggactct ttgaaactgt gcaacatctg
     4501 ccgctggggt ttcgtactcc ggtcaataac ggcggcacgg atctgtccgc gggccagcgt
     4561 cagttgattg ccctcgcgcg cgcccaactg gcacaggcgc acattctgct gctcgacgag
     4621 gcgacagcac gtatcgaccg cagcgccgag gagcgcttaa taacctcgct taccggagtg
     4681 acgcataccg agaaacgcat cgcgcttatc gtcgcgcacc gactgaccac cgctcgccgc
     4741 tgcgatgtta ttgtcgtaat cgataaagga tgtatcgctg aatatggcag ccatgagcag
     4801 ttgatagcgg ctcatggcct gtatgctcgt ctgtggcggg ccagcgtcgg ccagacacgc
     4861 gatacgcaag gagaggtcgt aggatagttt ttatcgccac gatttacgca aaagaaagcc
     4921 cgcaagcggc tgttcctgta acagccgctt tagctattga tactgaccga aatataaacg
     4981 agatggaata caaagaatga gactgagccc gcccgtcgct cctgtcgcta tacagaccgc
     5041 tacgcgcctt cgccgtcaac tcgccgccgg aagccaggtt gacgcttctc acttctggcg
     5101 agaagcaaac tcgctcgcgc tgccgctggt gacagccatt aacggcgcag acgatgaacg
     5161 ggaagtcacc ttcctgtggc gtgccgcctc tcctctgcgg ggggtttatg ttcgcctgaa
     5221 ccgtgtcacc gataaagata acgtggcgaa aggtatgatg acgcaactgc ccacaacgga
     5281 tatctggcat ctgacgcttc gcttaccggc gtcctactgc ggttcctata cgatggtcga
     5341 aataccaccg aaaaccccgg acgagacggt gttgcagctt ggaagccgtt tcgcctccct
     5401 tgtcgggaag gcggacccac tgaacagcac gccgggaata aatgttcggg gcaatgcgca
     5461 ggagtccgtt ctggcgttgg atcatgcccc ggcacaggag gagtggtcag gctgtcgcgc
     5521 ttacgccggg cagcttttca cctcagaaca tcggctcgcc ggacaacgtc gccgtgtgcg
     5581 gctgtatctt cctgacgttc ctgtcgaaca accgctgggc ttgctggtac tcacggatgg
     5641 cgagatctgg ttcgaccatc ttggggtaag cgccgccatt gacgccgcca tccgcagcgg
     5701 acgcatcgcg ccggtggccg tactcggcgt tgataatatc aatgcgcgtg aacgcgtcgc
     5761 aatcctcggc ggtcgccgcg agctggtgct cgacattgcc gaacgcctgc tgccaaccct
     5821 tcgcgccaaa tacccggaac gacagtgggc ggaccgtaca caaacggtgc tggcagggca
     5881 aagcctcggc ggcgtgaccg cgctgatggc ggcccgccac gcgccagaga gcttcggcct
     5941 ggtgctgagc cactccccct caatgtggtg gacgccggac aaccgcaatc gcccgcccca
     6001 tttcagcgca gaagagcgct catgggtcag cgaacatgtg ttatccgcgc cctcgccagc
     6061 cgtacgtacg catctgtgcg tgggatcgct ggaaggttcg acggtcccgc aggtcaaaca
     6121 gttgcatgaa aaattgcgcg ccgccggtgt tgaaagccat tgctgcgtgt acaccggcgg
     6181 tcacgattat gcctggtggc gcggcgcgct gattgacgga ttacgtctac tgccccgata
     6241 aaacttcacc tgccaaaaag gaataacatc cgatgtatgg tcgccagtac cacaacaagt
     6301 gctatcgcgt ggcgctattt ttagtgagtt tttgttttag cgcgctgagt tatgcgcagc
     6361 cggatatgca gccattaggg ccgaatatgg ctgataaagg ttcgggatat taccatttta
     6421 gggtcaatga ctttcaatct gccgatggcg caagacatta ccgggtatgg accgctattc
     6481 ccaataaagc cgccccgccg tcgggttatc ctgtcttata tatgctggac ggcaacgcag
     6541 tgatggacag gctgccggag acgctgctca aacaactggc agaccactcg ccgccggtga
     6601 ttgtggcgat tggctatcag actaacctgc cgtttgatct taacggcaga gcttatgact
     6661 atacgccggc gccgggaatc gatcgcgatg acagtgaaaa taacccgcgt tttcatcgta
     6721 agaccggcgg cgggccagcg ttccgccagc tactggagag acatatcgcg ccgcaggtgg
     6781 aacaaggaat aaccatcaac cccgaacggc gcgggatatg gggacattct tatggcggcc
     6841 tgttcgtttt ggactcctgg ctgtcgtcat ccttctttca tatctattac agcgccagcc
     6901 cgtcactcag cagggataac tttgccctgt tgaatcgcct tacggcagtg aagccgtcgc
     6961 cgttctgcca taaaaaactc atcataatgg aaggttcagc gtcgaatggg gatagcaggc
     7021 aacgccagat ggccgagctc ctgcaaaaag ttcaggagac cgtgagaacg cttgagaaca
     7081 acggcgttaa cgcggccctg cagcattacc cgggcctggg ccacgggccc atgtttaacg
     7141 cctcttttcg tagtgcattg ctgggtatca gtcgcgaacc ggcaagctaa gaaccacgct
     7201 gccattaacc cgtcgccaga atatgcccgc cagcggcggg cataacccat caaaacgagg
     7261 ccgtcacacc ggcataataa gcccgacccg gttcgttata ggtatttgcc ccttcggcgg
     7321 agcgatagat ctgtttatcg aagatattgc tgataccgac attaagacgc aggttcttat
     7381 tgatatcgta gttaacgtta gcgccgacca gtgagtaagc ccccagcgct ttcccggaca
     7441 atcctttggt ctcttcacta cgcgactccg catgtgttcg cggtttttgc ttgccgtata
     7501 acgtccagtt gacgttagcg gagagcgcgt tggtgatagt ccagtcgagg aaggtattca
     7561 ccgtatattt cgggattatc gataagggat taccggtatc tttttgctca gaagtgatca
     7621 tataagtcgc attggtattc cagttcagac ggtccggcat cagcggaaca gccatgctgg
     7681 cttcaatacc ttcaatcagc gctttaccgc cgttctgcca ctgcaataca taagcgccag
     7741 atgcgcttct gccaataatc tgatcacctg cgacaatctt attctgataa tcgttacgga
     7801 aatacgttac gcttgcgtga taatcgtcta cggtaaattc cagcccaatc tctttattga
     7861 tactaatttc aggatcgagg ttcttattac caaccaggta acagccgccc gacgtaatat
     7921 cttttggaca accgttgcct ttcgaataga gtaaataccc ctcactggtt tgatacaagt
     7981 tcggtgcctt aaaggcccgg gcaataccgg ctttcacctt gacgaattca cctaactcct
     8041 gggaaaggtt aagactggga ctaaaattac tcccggattc gctcaaatag tcaaaacgca
     8101 gacccggaat aatattggta ccggccatgg gttcgatatt atcttcaacg tacagcgcac
     8161 tgatttccga tttattttta ctgctacggt tagccgccga accgggaatc ccggcgatat
     8221 tgctatcctt aaccgtcaga ctggtagagg aaggatcgtt cagctcatcg cggttccact
     8281 ccgcgccgac ggtgagcgtt tgctcaaata gccatatcac cgggacattc acctcgccgc
     8341 tggtgcgata cgaggtcagg cggttagtgg tgaacgtctg gtcgttggta atacgcccct
     8401 cgccgccgcc ggagagtccc tcattcatgc gggtattatc ggttttttca tagtagaacc
     8461 ccaggcggct ttgcccccag ccccagatgc cgttatgagt tagaccgtaa ttctgccggt
     8521 acaggcgatt ggtctcccgc ccggactgcg ccagactttt ggtaaccgcg tttgaattac
     8581 tgttttgcgt atcgccggca tagatattcc cctgccgact gtatcccgct tcaaaatcaa
     8641 ggatttgctg cggggtcatt ttccatgaga agacgctatt aatatcttta ttggtgaccc
     8701 cctcccgtcc ggcggcattt ttggtaccgg cggaggagtt aatatcccag ctgtcggcat
     8761 cggttctgtt gagattaccg tacaggcgca tcgtcaacgt atcaccagcc aacgggccgc
     8821 taaggctaaa gttaccccgc cgggtgtcac cttctttgct gctttccggg tagttggtat
     8881 aaagcgacag cgagccatgc cagtcgttag tggggcgttt ggtgatgatg ttcaccaccc
     8941 cgcctgcggc accggagcca tagcgcgcgg cggcgggccc acggatcatt tcaatacgtt
     9001 ctaccatctc cggcggcacc cagttcgtat cgccacgggt gtcgcgttct ccgcgccagc
     9061 tatagcgaac cgaatttcgc gacgtcaccg gcacgccgtc aatcagcact aaggtatttt
     9121 ccggccccat accacgaata tcaatttgtc ggttatttcc gcgcgtcccc gaggcgctat
     9181 tgctggtaag attaacccca ggcatcttac gaataatatc ggcaagatcg ttaacgggag
     9241 gattcttctg aatatcgtca cgagtaataa tcgaaacgcc cggctgttgc tttaatactt
     9301 gctcggcagt ggattcaacc actatcgttt cgccgttgtc gtctgtagat tctgctgctg
     9361 ataatggact attaatccct gtagaaacca cggttattaa ccagatgaac ttcttaactc
     9421 tcatacccat tccctaaata atgtctaaag tagcgctgtt gccctcaagc tc
//
LOCUS       DAJVBX010000181         9446 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.181, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000181 DAJVBX010000000
VERSION     DAJVBX010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 9446)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9446)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9446
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.181"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..1685
                     /locus_tag="OPV72_003647"
     CDS             <1..1685
                     /locus_tag="OPV72_003647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="aryl-sulfate sulfotransferase"
                     /protein_id="HCR9915838.1"
                     /translation="MNPYDIAPLTAVIRNGGYQLRDVHVRIVPKENGQEIAYKVNNKY
                     LLTYGGIPVFGLYPDYVNTVEVEYTRIQGSKTENIKESYKMYAPPAYSESAGTKEEQS
                     ALFTIDVKKVSPEFKDRLYLLNNTKDKSGNGTRTVWNNPTGGALEWNFTTANAIIDTS
                     GDIRWFMNPSSIYDLKSIYRAGVMMGFKQNQDGALSWGYGQRYVKYDIMGREIFNRRL
                     PDNYNDFSHSMDNAPNGHYFLRVASSNYKRPDGKNVRTVRDVIAEVDQNGVVVDEWRL
                     FDILDPYRDVIMKTLDQGAVCLNIDASQSGHTLSEEDLAALDSSDKFGDIVGSGAGRN
                     WAHVNSVDYDSEDDSIIISFRHQSAIIKIGRDKKVKWILGTPAGWKAPFNAAILTPVD
                     SKGQKISCQESGCEGDFDWTWTQHTAFKIDSKSKGDILYLSAFDNGDGRGLEQPAMQS
                     MKYSRSVIYKIDQKNKTVQQIWQYGKERGNEWFSPVTSITEYQTDKNSVFVYSATAGG
                     EFDLSVGAFTSLPNPYLEEFRWGEKEPAVEMQIHGARGYQAMPFSLTKALTE"
     gene            complement(1882..3045)
                     /gene="fadA"
                     /locus_tag="OPV72_003648"
     CDS             complement(1882..3045)
                     /gene="fadA"
                     /locus_tag="OPV72_003648"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase FadA"
                     /protein_id="HCR9915839.1"
                     /translation="MEQVVIVDAIRTPMGRSKGGAFRNVRAEDLSAHLMRSLLARNPS
                     LTAATLDDIYWGCVQQTLEQGFNIARNAALLAEIPHSVPAVTVNRLCGSSMQALHDAA
                     RMIMTGDAQVCLVGGVEHMGHVPMSHGVDFHPGLSRNVAKAAGMMGLTAEMLSRLHGI
                     SREMQDQFAARSHARAWAATQSGAFKTEIIPTGGHDADGVLKQFNYDEVIRPETTVEA
                     LSTLRPAFDPVSGTVTAGTSSALSDGAAAMLVMSESRARELGLKPRARIRSMAVVGCD
                     PSIMGYGPVPASKLALKKAGLSASDIDVFEMNEAFAAQILPCIKDLGLMEQIDEKINL
                     NGGAIALGHPLGCSGARISTTLINLMERKDAQFGLATMCIGLGQGIATVFERV"
     gene            complement(3055..5244)
                     /gene="fadB"
                     /locus_tag="OPV72_003649"
     CDS             complement(3055..5244)
                     /gene="fadB"
                     /locus_tag="OPV72_003649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid oxidation complex subunit alpha FadB"
                     /protein_id="HCR9915840.1"
                     /translation="MLYKGDTLYLDWLEDGIAELVFDAPGSVNKLDTATVASLGQALE
                     VLEKQHDLKGLLLRSNKAAFIVGADITEFLSLFLVPEEQLSQWLHFANSVFNRLEDLP
                     VPTLAAVNGYALGGGCECVLATDYRLATPDLRIGLPETKLGIMPGFGGSVRLPRMLGA
                     DSALEIIAAGKDVGAEHALKIGLVDGVVKQEKLIEGAIAVLRQAITGDLDWRAKRQPK
                     LEPLKLSKIEAAMSFTIAKGMVAQTAGKHYPAPMTAVKTIEAAARFGREEALNLENKS
                     FVPLAHTNEARALVGIFLNDQYVKGKAKKLTKDIETPKQAAVLGAGIMGGGIAYQSAW
                     KGVPVIMKDINDKSLNLGMTEAAKLLNKQLERGKIDGLKLAGVISTIHPTLDYAGFDR
                     VDVVVEAVVENPKVKKAVLAETEQKVRPETVLASNTSTIPIGELASALERPENFCGMH
                     FFNPVHRMPLVEIIRGEKSSDETIAKVVAWASKMGKTPIVVNNCPGFFVNRVLFPYFA
                     GFSQLLRDGADFRKVDKVMEKQFGWPMGPAYLLDVVGIDTAHHAQAVMAAGFPQRMQK
                     EYRDAIDALFDASRFGQKNGLGFWRYKEDSKGKPKKEEDAAVDDLLASVSQTKRDFSD
                     DEIIARMMIPMINEVVRCLEEGIIASPAEADMALVYGLGFPPFHGGAFRWLDTQGSAK
                     YLDMAQQYQHLGPLYEVPEGLRDKTRHNEPYYPPVEPARPVGSLKTA"
     gene            5434..6765
                     /gene="pepQ"
                     /locus_tag="OPV72_003650"
     CDS             5434..6765
                     /gene="pepQ"
                     /locus_tag="OPV72_003650"
                     /EC_number="3.4.13.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020801804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidase"
                     /protein_id="HCR9915841.1"
                     /translation="MESLAALYKNHIVTLQERTRDVLARFKLDALLIHSGELFNVFLD
                     DHPYPFKVNPQFKAWVPVTQVPNCWLLVDGVNKPKLWFYLPVDYWHNVEPLPTSFWTE
                     EVEVVALPKADGIGSQLPAARGNIGYIGPVPERALQLDIAASNINPKGVIDYLHYYRA
                     YKTDYELACMREAQKMAVSGHRAAEEAFRSGMSEFDINLAYLTATGHRDTDVPYSNIV
                     ALNEHAAVLHYTKLDHQAPSEMRSFLLDAGAEYNGYAADLTRTWSAKSDNDYAHLVKD
                     VNDEQLALIATMKAGVSYVDYHIQFHQRIAKLLRKHQIITDMSEEAMVENDLTGPFMP
                     HGIGHPLGLQVHDVAGFMQDDSGTHLAAPSKYPYLRCTRVLQPRMVLTIEPGIYFIES
                     LLAPWREGPFSKHFNWQKIEALKPFGGIRIEDNVVIHENGVENMTRDLKLA"
     gene            6765..7379
                     /locus_tag="OPV72_003651"
     CDS             6765..7379
                     /locus_tag="OPV72_003651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMPACT family protein"
                     /protein_id="HCR9915842.1"
                     /translation="MDSWLIPAAPVTVVEEIKKSRFITLLAHTDGVEAAKAFVELVRA
                     EHPDARHHCAAWVAGAPDDSQQLGFSDDGEPAGTAGKPMLAQLMGSGVGEITAVVVRY
                     YGGILLGTGGLVKAYGGGVNQALRQLATQRKTPLTEYTLQCEYGQLAGIEALLGQFAG
                     KIVSSDYQASVRLRVALPFAHVNAFSTKLADFSRGSLQLLAIEE"
     gene            7418..8869
                     /gene="trkH"
                     /locus_tag="OPV72_003652"
     CDS             7418..8869
                     /gene="trkH"
                     /locus_tag="OPV72_003652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkH"
                     /protein_id="HCR9915843.1"
                     /translation="MHFRAITRIVGLLVILFSGTMILPGLVALIYRDGAGGAFTQTFF
                     VALAIGSILWWPNRREKGELKSREGFLIVVLFWTVLGSVGALPFIFSESPNLTITDAF
                     FESFSGLTTTGATTLVGLDSLPHAILFYRQMLQWFGGMGIIVLAVAILPVLGVGGMQL
                     YRAEMPGPLKDNKMRPRIAETAKTLWLIYVLLTVACALALWFAGMPAFDAIGHSFSTI
                     AIGGFSTHDASVGYFDSPTINTIIAIFLLISGCNYGLHFSLLSGRSLKVYWRDPEFRM
                     FIGVQLTLVVICTLVLWFHNIYDSALTTLNQAFFQVVSMATTAGFTTDSIARWPLFLP
                     VLLLCSAFIGGCAGSTGGGLKVIRILLLFKQGNRELKRLVHPNAVYSIKLGNRALPER
                     ILEAVWGFFSAYALVFIVSMLAIIATGVDDFSAFASVVATLNNLGPGLGVVADNFASM
                     NPVAKWILIANMLFGRLEVFTLLVLFTPTFWRE"
     gene            8881..9426
                     /gene="hemG"
                     /locus_tag="OPV72_003653"
     CDS             8881..9426
                     /gene="hemG"
                     /locus_tag="OPV72_003653"
                     /EC_number="1.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="menaquinone-dependent protoporphyrinogen IX
                     dehydrogenase"
                     /protein_id="HCR9915844.1"
                     /translation="MKTLILFSTRDGQTREIASYLASELKEMGIWADVVNLHRAEEPD
                     WDSYDRVVIGASIRYGHYHSAFQEFVKKYATRLNGMPSAFYSVNLVARKAEKRTPQTN
                     SYARKFLMSSPWRPDYCAVIAGALRYPRYRWYDRLMIKLIMKMSGGETDTSKEVVYTD
                     WEQVAHFAREIAHLTNKSSAK"
BASE COUNT         2154 a         2439 c         2559 g         2294 t
ORIGIN      
        1 ttatgaaccc ctatgatatc gcgccgctaa ccgccgttat tcgtaatggc ggttaccagt
       61 tacgtgacgt gcatgtgcgg attgtaccca aagaaaatgg ccaggagatc gcgtataaag
      121 ttaataataa atacctttta acgtatggcg gtattcccgt ctttggtctt tacccggatt
      181 atgtcaatac cgttgaagtt gaatatacaa gaatccaggg tagtaaaacc gaaaatataa
      241 aagaaagcta taaaatgtat gcaccgcctg cttatagtga atcagcgggt acaaaagaag
      301 aacaatcagc actctttact atcgatgtta aaaaggtttc cccagaattt aaagatcgct
      361 tgtatctttt gaataatacg aaagataagt ctgggaatgg aacgcgtact gtctggaaca
      421 accctactgg gggtgcatta gaatggaact tcactacagc taacgctatt atcgacacct
      481 ccggtgatat tcgttggttt atgaatccaa gttcaattta tgatttaaag tcaatttatc
      541 gtgctggcgt tatgatgggc tttaaacaaa accaggatgg cgcactatcg tggggctacg
      601 gtcagcgtta tgtgaaatac gatatcatgg ggcgtgaaat cttcaaccgc cgcctgccgg
      661 ataattataa cgatttttca cactcaatgg ataacgcgcc caacggtcac tacttcctgc
      721 gtgtagccag ctctaactat aaacgtcctg atgggaaaaa tgttcgtacc gtgcgtgatg
      781 tgattgccga agttgatcag aacggcgtgg tagtggatga atggcgtctg tttgatatcc
      841 tcgatcctta tcgtgatgtg ataatgaaaa ccctcgatca gggcgcagtg tgcctgaata
      901 tcgacgccag ccagtccggc catacgttga gcgaagaaga tctggcggcg ctggactcct
      961 ccgacaaatt cggggatatc gtgggtagtg gggctggccg caactgggcg catgtcaaca
     1021 gcgtcgacta tgacagtgaa gatgattcca tcatcatcag cttccgccac cagagtgcga
     1081 ttatcaaaat cggtcgcgat aagaaagtga agtggatact tggtacgcct gctggctgga
     1141 aagcgccatt taatgccgca attctgacgc ctgtggatag caaaggccaa aaaatttcct
     1201 gccaggaaag tggctgtgag ggtgacttcg actggacatg gacgcaacat acggccttta
     1261 aaattgatag taagagtaaa ggcgatatct tatacctttc cgctttcgac aatggtgatg
     1321 gccgcggctt agaacagcct gctatgcaga gtatgaaata cagccgctcc gtgatttaca
     1381 aaatcgacca gaaaaacaag acagtccaac agatctggca atacggtaaa gagcgcggga
     1441 acgagtggtt tagcccggta acctctatca ccgagtacca gactgacaag aattctgtgt
     1501 tcgtgtattc cgcaacagca ggtggtgagt ttgatttgtc ggtaggcgca tttaccagct
     1561 tgcctaaccc gtatctggaa gagttcagat ggggagaaaa agagcctgcg gtcgaaatgc
     1621 aaatacatgg tgcgcgtgga tatcaggcta tgccatttag cctgaccaaa gcgcttactg
     1681 agtagagcag gccacacggt gaaaaaaccc gcccctgacg ggcgggaaaa acggcaacta
     1741 aactgttccc cgtcataact cacgctgcct ctttgttggc tgcctttgtt caccccgggc
     1801 atatagttat ctatgttccc ggggattcgc tcagttgccg ccgcgctgca acgtgaatta
     1861 tttaggggac attatcttta attaaacccg ctcaaacacc gtggcgatgc cctgacccag
     1921 accaatacac atcgtcgcca gaccaaactg cgcgtctttg cgctccatca ggttgataag
     1981 cgtggtgctg atacgtgctc cggagcagcc gagcggatgg ccaagcgcga tcgcgccgcc
     2041 gttgaggttg atcttctcgt ctatctgctc catcaatccc agatccttaa tgcatggcag
     2101 gatctgtgcg gcaaacgctt cgttcatctc aaacacatcg atatcgctgg ccgacagtcc
     2161 cgcttttttc aacgccagtt ttgacgccgg aaccggcccg taacccataa ttgacggatc
     2221 acaacccacc actgccattg agcgaatacg ggcgcgaggt ttcagaccca gctcacgggc
     2281 acgactttcg ctcattacca gcatggcggc tgcgccatcg gaaagcgcgg atgaggtgcc
     2341 cgccgtgacc gtgccactaa ccggatcaaa tgccggacgc agcgttgata gcgcttcgac
     2401 cgtggtttcc gggcggatca cttcatcgta gttaaactgc ttcaacacgc cgtctgcatc
     2461 atgaccgcca gtcgggataa tctccgtttt gaatgcgcca gactgggtgg cggcccaggc
     2521 gcgagcgtga gaacgcgcgg cgaactggtc ctgcatttcc cggctaatgc cgtgcaggcg
     2581 ggagagcatt tccgccgtta gccccatcat ccctgctgct ttggcgacgt tgcggctcag
     2641 acccgggtga aaatccacgc cgtggctcat cggcacgtgc cccatatgct ccacgccgcc
     2701 aaccagacaa acctgcgcat cgccggtcat gatcattcgc gctgcatcgt gtaacgcctg
     2761 catcgaggaa ccacacagac ggttgacggt gaccgccggt accgaatggg gaatttctgc
     2821 cagcagcgcg gcgttacggg caatgttgaa gccttgctcc agcgtttgtt gtacgcagcc
     2881 ccagtaaata tcatcgaggg tcgccgctgt aagcgacgga ttacgcgcca gcaggctacg
     2941 cattaagtgg gcggagagat cttctgcccg cacgttgcga aacgcgccgc ccttcgaacg
     3001 gcccatcggg gtgcgaatgg catcgacaat gacaacctgt tccattgtga ctccttaagc
     3061 cgttttcaga gaaccaaccg gacgggctgg ttcaaccggg ggataatacg gttcgttatg
     3121 gcgcgtttta tcacgcagcc cttccggcac ttcatacagc gggccgaggt gttgatactg
     3181 ctgcgccata tcaagatatt tcgcgctgcc ctgtgtatcc agccagcgga atgcgccgcc
     3241 gtggaacgga gggaagccca ggccgtagac cagcgccata tcggcttccg ccgggcttgc
     3301 gataatgcct tcttccagac agcgaaccac ttcgttaatc atcgggatca tcatacgggc
     3361 gattatctcg tcgtcgctga agtcgcgttt cgtctgactg acgcttgcca gcaggtcatc
     3421 caccgcagca tcttcttctt tcttcggctt acccttgctg tcttctttat agcgccagaa
     3481 gcccagaccg tttttttgcc caaaacggct ggcgtcaaac aatgcgtcga tcgcgtcgcg
     3541 atactctttc tgcatccgtt gtgggaagcc tgccgccatt accgcctgcg cgtggtgggc
     3601 ggtatcaata cccaccacgt cgagcagata ggccgggccc atcggccagc cgaactgttt
     3661 ttccatcact ttatcgactt tgcggaaatc cgcgccgtcg cgcagcagtt gactgaaacc
     3721 ggcgaaatag gggaacagca cgcggttaac aaagaagccg gggcagttgt tgactacaat
     3781 cggtgtcttg cccattttgc tggcccaggc gacgactttg gcaatggttt cgtctgaact
     3841 cttctcgccg cgaatgattt caaccagcgg catccggtgt accgggttga agaagtgcat
     3901 tccgcaaaag ttttccggac gttccagggc gcttgccagt tcgccaattg ggatggtgga
     3961 ggtatttgag gccagcacgg tttctgggcg cactttctgc tcggtttccg ccagtaccgc
     4021 ttttttgact ttcggatttt cgactaccgc ttcgacaaca acatctacgc gatcgaaacc
     4081 ggcataatcg agagtcgggt ggatggtcga aatgacgccc gccagcttca gaccgtcgat
     4141 cttgccgcgc tccagctgtt tgttcagcag cttggccgct tcggtcatgc cgaggttcaa
     4201 cgatttatcg ttgatatctt tcatgatgac cggtacgcct ttccaggccg actggtaagc
     4261 gataccgccg cccataatgc ccgcgcccag tacggctgcc tgtttcggcg tctcaatatc
     4321 tttggtcagc tttttggctt taccttttac atattgatcg ttgaggaaga taccgaccag
     4381 cgcacgagcc tcattggtat gcgccagcgg aacaaagctt ttattttcca gattcagcgc
     4441 ttcttcacga ccaaaacgcg cggcggcttc aatggttttc actgcggtca tcggcgccgg
     4501 ataatgttta cccgccgttt gtgcgaccat gcctttagcg atggtaaagc tcatcgccgc
     4561 ttcaattttg ctgagtttca acggttccag tttcggctgg cgtttagctc tccagtcgag
     4621 atcgccggta atggcctggc gtaacaccgc tatcgcgcct tcaattagct tctcttgttt
     4681 gaccacgccg tccacaaggc cgattttcag cgcgtgctca gcaccgacat ctttacctgc
     4741 cgcgataatc tccagcgcgc tgtccgcgcc cagcatacgc ggcagacgaa cggagccgcc
     4801 gaaacccggc atgatgccca gtttagtttc cggcagaccg atacggaggt ctggcgtcgc
     4861 cagacggtaa tcggtcgcca gcacgcattc acacccgccg cccagcgcat agccgtttac
     4921 ggcggcaagg gtcggtacgg gtaaatcttc cagacggtta aagacgctat tagcgaaatg
     4981 cagccattgg cttaactgct cttcggggac gaggaacagt gaaagaaatt cggtgatgtc
     5041 cgcgccgaca ataaaggccg ctttattaga gcgcagcagc agccctttta aatcgtgttg
     5101 cttttccagc acctcaagcg cctggccgag gctggcgacg gttgcggtgt cgagtttatt
     5161 gaccgagcct ggagcatcga acaccagttc ggcgatgcca tcttccagcc agtcgaggta
     5221 cagggtgtcg cctttataaa gcatgtcagt ctcctgaatc cacaaggtga tctggtcgta
     5281 tcagatgaag cgaagtgtgt attttgtgtt aataaaatgc aaataaatga ttaaagaaat
     5341 gccgatgtga tcacgctcgg cagagatcac gctctcgtgg ggcgatgtgc taagatgcgg
     5401 aaacttgagg tcaaaaaaac agaagggtaa aaaatggaat cactggccgc gctctataaa
     5461 aatcatattg ttaccttaca agaacggacg cgcgatgttc tggcgcgctt taagctggat
     5521 gcgttactta ttcattccgg cgagcttttc aacgtctttc tcgacgatca cccttatccg
     5581 tttaaggtca atccgcagtt taaagcgtgg gtgccggtaa ctcaggttcc aaattgctgg
     5641 ctgctggtcg atggcgtcaa caaacccaaa ttgtggtttt atctgccggt cgattactgg
     5701 cataacgttg aaccgctgcc aacgtcattc tggacagaag aagtcgaggt cgtcgcctta
     5761 ccgaaagcgg atggcatcgg cagccaactt cctgccgcgc gtggcaatat cggctatatc
     5821 ggcccggttc ctgagcgcgc gctacaattg gatatcgccg ccagcaacat caacccgaaa
     5881 ggtgttatcg actatctgca ttactaccgc gcctataaaa cggattatga actggcctgt
     5941 atgcgcgaag cgcagaaaat ggcggtgagc ggtcatcggg cggcggaaga ggccttccgt
     6001 tccggcatga gcgagtttga catcaacctg gcgtacctga ccgccacggg acatcgcgat
     6061 accgatgttc cgtacagcaa cattgtggcg ctgaacgaac atgccgccgt gctgcattac
     6121 acgaaactgg atcatcaggc accgtctgaa atgcgcagtt tcctgctgga tgcgggcgcg
     6181 gaatacaacg gctacgcggc ggatctgacg cggacctggt cggcgaaaag cgataacgac
     6241 tacgcccacc tggtgaaaga tgttaacgac gaacagttgg cgctgatcgc taccatgaag
     6301 gcgggcgtta gctatgtgga ttatcatatt cagttccatc agcgcatcgc aaagctgctg
     6361 cgtaagcatc aaatcattac cgacatgagt gaagaggcga tggtggaaaa tgatctcacc
     6421 gggccgttta tgccgcacgg tattggtcat ccgttgggtc tgcaggtaca cgatgtggcc
     6481 gggtttatgc aggatgattc cggtacgcat ctcgccgcgc cgtccaaata cccgtatctg
     6541 cgctgcacgc gtgtgttaca gccgcgaatg gtgttgacca tcgaaccggg gatttacttc
     6601 atcgaatcgc tgttagcgcc gtggcgcgaa gggccattca gcaagcactt caactggcag
     6661 aaaattgaag cgctcaagcc tttcggcggt attcgcattg aagataacgt ggtcatccac
     6721 gaaaacggcg tggaaaacat gacgcgggat ttaaaactgg cgtaatggac agttggttaa
     6781 tccctgcagc gccggtcacc gttgttgaag agatcaaaaa aagccgcttt attacgctat
     6841 tggcgcatac cgatggcgta gaggcggcga aagcgtttgt tgagttagtc agagctgagc
     6901 accctgatgc gcgccaccat tgtgcggcgt gggtggcggg tgcgccggac gactcacaac
     6961 aactgggctt ttcagacgac ggcgagccgg cgggaacggc aggcaagccg atgcttgcgc
     7021 aattgatggg cagcggcgtc ggagaaatta ctgccgtcgt cgtgcgctac tatggtggta
     7081 ttctgctggg tacgggcggg ctggtaaaag cctatggcgg cggtgtgaat caggcattac
     7141 gtcagcttgc cacacaacgc aagacgccat taaccgaata tactttgcag tgtgagtacg
     7201 gtcagttggc cggaatcgaa gcattattag gacagtttgc cgggaagatc gtttccagcg
     7261 attatcaggc gtctgttcgg ctcagggtgg cgcttccttt tgctcatgtg aatgcatttt
     7321 ccacaaaact ggcggatttt agccgtggtt cattgcaatt gttagcgatt gaagaataat
     7381 ccccacctca tttttaagaa taaaggaagc ggcagagatg cattttcgcg ccattacccg
     7441 aatcgttgga ctactggtta tcttattttc ggggacaatg attctcccgg gactggtagc
     7501 gctaatatat cgtgatggcg caggaggagc gttcacgcag accttttttg tcgcgctggc
     7561 gatcggttcc atactgtggt ggccaaatcg tagggaaaag ggcgagctga aatcccgcga
     7621 aggatttctt atcgtggtgc tgttctggac cgtgctgggc agcgtgggtg cgctgccgtt
     7681 tattttctcg gaaagcccaa acctcaccat taccgatgct ttttttgaat cgttctccgg
     7741 gttaaccacc acgggcgcca ctacgctggt ggggctggat tcattaccgc acgccattct
     7801 cttttatcgt cagatgctgc aatggtttgg cggtatgggg atcattgtgc tggcggtggc
     7861 gattctccct gtcctcggcg tcggggggat gcagctctat cgggcagaaa tgccggggcc
     7921 gctcaaagat aacaaaatgc gcccgcgtat tgccgagacg gcgaaaacgc tgtggcttat
     7981 ctatgtcttg ctaacggtag cctgcgcgct ggcgctatgg tttgcaggga tgcccgcgtt
     8041 tgacgctatc ggacacagct tctccactat cgctatcggc ggcttctcaa cgcatgacgc
     8101 cagcgtaggc tattttgata gtcccactat taataccatc atcgctattt tcctgctgat
     8161 ctccggttgt aactatggcc tgcatttctc tttattaagc gggcgtagcc tgaaggtata
     8221 ctggcgcgat ccggaattcc gcatgttcat cggcgtacag ttgacgctgg tggtgatctg
     8281 cacgctggta ctgtggttcc ataatatcta cgactcggcg ctgacaacgc taaatcaggc
     8341 gttcttccag gttgtgtcga tggcgacaac ggcagggttt accacggaca gcattgcgcg
     8401 ctggccgctg tttttgcccg tcttgctgct atgttccgcg tttattggcg gttgcgccgg
     8461 gtcaacgggc ggggggttaa aggtcatccg tattctgttg ttatttaaac aggggaaccg
     8521 cgaactcaaa cgtctggtgc atccgaatgc cgtttacagt attaagctgg ggaaccgggc
     8581 gctgccagag cgtattctgg aagccgtctg gggattcttt tctgcctacg cgctggtatt
     8641 tatcgtcagt atgctggcca ttatcgctac aggcgtagat gatttctcgg ctttcgcctc
     8701 ggtagtggct acgcttaata acctgggacc ggggctgggg gtggttgctg ataacttcgc
     8761 cagtatgaat ccggttgcga aatggatact catcgccaac atgctatttg gtcgtctgga
     8821 agtattcact ttgctggtac tttttacccc gactttctgg cgtgaataat ggagtaacac
     8881 gtgaaaacat tgattctttt ctctacccgg gacggacaaa cgcgcgaaat tgcctcttat
     8941 ctggcttctg aactcaaaga gatggggatc tgggccgatg tcgttaatct gcatcgcgca
     9001 gaagagcctg actgggatag ctatgatcgc gtagtgattg gcgcgtctat tcgttatggt
     9061 cattaccaca gcgcctttca ggagtttgtt aagaaatatg ccacgcggtt gaacggaatg
     9121 ccgagcgcct tttattccgt taacctggtg gcgcgtaaag ctgaaaaacg gacgccgcag
     9181 actaacagct acgcgcgtaa gtttttaatg agttctccgt ggcgacctga ctactgtgcc
     9241 gtcattgcag gcgcgcttcg ctatccccgc tatcgctggt atgaccgtct gatgatcaag
     9301 cttattatga agatgtcggg cggcgaaacg gataccagta aagaagtggt gtacaccgac
     9361 tgggagcaag ttgcgcactt tgcccgtgaa atagcccatt taaccaacaa atcgtcggca
     9421 aaataaacgc aaagaataaa aagtgc
//
LOCUS       DAJVBX010000182         9420 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.182, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000182 DAJVBX010000000
VERSION     DAJVBX010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 9420)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9420)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9420
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.182"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            39..1013
                     /gene="cysB"
                     /locus_tag="OPV72_003654"
     CDS             39..1013
                     /gene="cysB"
                     /locus_tag="OPV72_003654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012017585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator CysB"
                     /protein_id="HCR9915845.1"
                     /translation="MKLQQLRYIVEVVNHNLNVSSTAEGLYTSQPGISKQVRMLEDEL
                     GIQIFARSGKHLTQVTPAGQEIIRIAREVLSKVDAIKSVAGEHTWPDKGSLYIATTHT
                     QARYALPGVIKGFIERYPRVSLHMHQGSPTQIAEAVSKGNADFAIATEALHLYDDLVM
                     LPCYHWNRSIVVTPDHPLAATSSITIEALAQYPLVTYTFGFTGRSELDTAFNRAGLTP
                     RIVFTATDADVIKTYVRLGLGVGVIASMAVDPLTDPDLVRIDAHDIFSHSTTKIGFRR
                     STFLRSYMYDFIQRFAPHLTRDVVDTAVALRSNEEIEAMFQDIKLPEK"
     gene            1273..1434
                     /locus_tag="OPV72_003655"
     CDS             1273..1434
                     /locus_tag="OPV72_003655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001308615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmiA family putative membrane protein"
                     /protein_id="HCR9915846.1"
                     /translation="MISDTDSMRLVMPSENQEPRRDPELKRKAWLAVFVGSALFWVVV
                     ALVIWHWWG"
     gene            1435..1605
                     /locus_tag="OPV72_003656"
     CDS             1435..1605
                     /locus_tag="OPV72_003656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915847.1"
                     /translation="MSITSERERVVAPPIQSGDDDNTPDTTVFRSVPQHWTLTPQQRA
                     FIDAFADEVSQK"
     gene            1990..4665
                     /gene="acnA"
                     /locus_tag="OPV72_003657"
     CDS             1990..4665
                     /gene="acnA"
                     /locus_tag="OPV72_003657"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase AcnA"
                     /protein_id="HCR9915848.1"
                     /translation="MSSTLREASKDTLQAKDKTYHYYSLPLAAKSLGDIARLPKSLKV
                     LLENLLRWQDGESVTDEDIQALAGWLKNAHADREIAWRPARVLMQDFTGVPAVVDLAA
                     MREAVKRLGGDTSKVNPLSPVDLVIDHSVTVDHFGDDDAFEENVRLEMERNHERYMFL
                     KWGKQAFSRFSVVPPGTGICHQVNLEYLGKAIWSELQDGEWIAYPDSLVGTDSHTTMI
                     NGLGVLGWGVGGIEAEAAMLGQPVSMLIPDVVGFKLTGKLREGITATDLVLTVTQMLR
                     KHGVVGKFVEFYGDGLDSLPLADRATIANMSPEYGATCGFFPIDAITLEYMRLSGRSD
                     DLIELVETYAKAQGMWRNPGDEPVFTSTLELDMGDVEASLAGPKRPQDRVALGDVPKA
                     FAASAELELNTAQRDRQPVDYTMNGQPYQLPDGAVVIAAITSCTNTSNPSVLMAAGLL
                     AKKAVTLGLKRQPWVKASLAPGSKVVSDYLAQAKLTPYLDELGFNLVGYGCTTCIGNS
                     GPLPEPIETAIKKGDLTVGAVLSGNRNFEGRIHPLVKTNWLVSPPLVVAYALAGNMNI
                     NLATDPLGYDRKGDPVYLKDIWPSAQEIARAVELVSSDMFRKEYAEVFEGTEEWKSIQ
                     VESSDTYGWQSDSTYIRLSPFFDEMQAQPAPVKDIHGARILAMLGDSVTTDHISPAGS
                     IKPDSPAGRYLQNHGVERKDFNSYGSRRGNHEVMMRGTFANIRIRNEMLPGVEGGMTR
                     HLPGTEAMSIYDAAMLYQQEKTPLAVIAGKEYGSGSSRDWAAKGPRLLGIRVVIAESF
                     ERIHRSSLIGMGILPLEFPQGVTRKTLGLTGEEVIDIADLQNLRPGATIPVMLTRADG
                     SKETVPCRCRIDTATELTYYQNDGILHYVIRNMLN"
     gene            complement(4721..5311)
                     /gene="ribA"
                     /locus_tag="OPV72_003658"
     CDS             complement(4721..5311)
                     /gene="ribA"
                     /locus_tag="OPV72_003658"
                     /EC_number="3.5.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase II"
                     /protein_id="HCR9915849.1"
                     /translation="MQLKRVAEAKLPTPLGDFLMVGFEELATGHDHAALVFGDISGKT
                     PVLARVHSECLTGDALFSLRCDCGFQLEAALTHIAEEGRGILIYHRQEGRNIGLLNKI
                     RAYALQDQGYDTVEANHQLGFAADERDFTLCADMFKLLGVDEVRLLTNNPKKVEILTE
                     AGINIVERVPLIVGRNPNNEHYLDTKAAKMGHLLSK"
     gene            5507..6271
                     /gene="pgpB"
                     /locus_tag="OPV72_003659"
     CDS             5507..6271
                     /gene="pgpB"
                     /locus_tag="OPV72_003659"
                     /EC_number="3.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase B"
                     /protein_id="HCR9915850.1"
                     /translation="MLSIARRTAAGAALLLIMPLAVWVSGWQWQPGHQVWWLKTLFWI
                     TETVTKPWGVITHVILCGWFLWCLRFRLRAAIMLFAILGGAIIVGQGVKSWVKERVQE
                     PRPFVVWLEKTHHIPVDEFYTLKRTERGHLVKEQLAGQQNIPVFLRQHWQKETGFAFP
                     SGHTMFAASWALLAVGLLWPRRRTFTIAFLLVWATGVMGSRLLLGMHWPRDLVVATLI
                     SWLLVTLATWLAQRICGPLMPPREEAQEIAEREQES"
     gene            6421..6729
                     /locus_tag="OPV72_003660"
     CDS             6421..6729
                     /locus_tag="OPV72_003660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LapA family protein"
                     /protein_id="HCR9915851.1"
                     /translation="MKYLLIFLLVLAIFVISVTLGAQNDQQVTFNYLLAQGEYRISTL
                     LAVLFAVGFAIGWLICGLFWLRVRVSLARAERKIKRLENKLSPATDVAVPADSSVVKE
                     "
     gene            6736..7905
                     /gene="lapB"
                     /locus_tag="OPV72_003661"
     CDS             6736..7905
                     /gene="lapB"
                     /locus_tag="OPV72_003661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapB"
                     /protein_id="HCR9915852.1"
                     /translation="MLELLFLLLPVAAAYGWYMGRRSAQQTKQDEANRLSRDYVAGVN
                     FLLSNQQDKAVDLFLDMLKEDTGTVEAHLTLGNLFRSRGEVDRAIRIHQTLMESASLT
                     YEQRLLAVQQLGRDYMAAGLYDRAEDMFNQLTDETEFRVGALQQLLQIYQLTSDWQKA
                     IEVAERLVKLGKDKQRIEIAHFYCELALQQMGNDDMDRAMALLKKGAAADKNSARVSI
                     MMGRVYMARGDYAKAVESLQRVIVQDKELVSETLEMLQTCYQQLGKNAEWAEFLRRAV
                     EENTGAGAELMLADILEAREGSDAAQVYITRQLQRHPTMRVFHKLMDYHLNEAEEGRA
                     KESLMVLRDMVGEQVRSKPRYRCQKCGFTAYTLYWHCPSCRAWSTIKPIRGLDGQ"
     gene            8096..8833
                     /gene="pyrF"
                     /locus_tag="OPV72_003662"
     CDS             8096..8833
                     /gene="pyrF"
                     /locus_tag="OPV72_003662"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HCR9915853.1"
                     /translation="MTFTASSSSCAITESPVVVALDYHERDKALAFVDKIDPRDCRLK
                     VGKEMFTLFGPQLVRDLQQRGFDVFLDLKFHDIPNTTARAVAAAADLGVWMVNVHASG
                     GARMMAAARDALAPFSKDAPLLIAVTVLTSMGTSDLHDLGVTLSPAEHAERLARLTQQ
                     CGLDGVVCSAQEAVRFKQAFGAAFKLVTPGIRPAGSEAGDQRRIMTPEQALSAGVDYM
                     VIGRPVTQSVDPAQTLKDINASLKREA"
     gene            8833..9159
                     /gene="yciH"
                     /locus_tag="OPV72_003663"
     CDS             8833..9159
                     /gene="yciH"
                     /locus_tag="OPV72_003663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response translation initiation inhibitor
                     YciH"
                     /protein_id="HCR9915854.1"
                     /translation="MSDSNSRLVYSTQTGRIEEPKTAPVRPKGDGIVRIQRQTSGRKG
                     KGVCLITGIEMNDAELTKLAAELKKKCGCGGAVKEGIIEIQGDKRDLIKSLLEAKGMK
                     VKLAGG"
     gene            complement(9279..>9420)
                     /locus_tag="OPV72_003664"
     CDS             complement(9279..>9420)
                     /locus_tag="OPV72_003664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycine zipper 2TM domain-containing protein"
                     /protein_id="HCR9915855.1"
                     /translation="WSKRDRNTAIGAGAGALGGAVLTDGSTLGTLGGAAVGGVIGHQV
                     GK"
BASE COUNT         2161 a         2268 c         2646 g         2345 t
ORIGIN      
        1 aaacgatggc ctgatggcgc taatctggat gatgtattat gaaattgcag cagcttcgtt
       61 acattgttga agtggttaat cataacctta acgtctcctc taccgctgag gggttgtata
      121 cttcccagcc ggggatcagc aagcaggtta ggatgctgga agatgagctt ggcatccaga
      181 ttttcgcccg cagtggtaag catctgactc aggtgacgcc cgcaggtcag gagattattc
      241 gtattgcgcg tgaggtgctt tccaaagtcg atgccattaa gtcggtcgcc ggcgagcaca
      301 cctggccgga taaaggctcg ctctatattg ccactaccca tactcaggcg cgttacgcat
      361 tgccaggcgt gattaaaggc ttcatcgagc gttacccgcg cgtttcgctg catatgcacc
      421 aggggtcgcc aacgcagatt gcggaagcgg tatcgaaagg gaacgccgat ttcgcgattg
      481 ccacggaagc gctgcattta tatgacgatc tggtgatgtt gccatgctat cactggaacc
      541 gttcgatagt ggtgacgccg gatcatccat tggcggcaac gtcttccata acgatcgaag
      601 cgctggcgca gtatccgctg gtgacgtata ccttcggctt taccgggcgt tccgaactgg
      661 ataccgcttt taatcgcgca gggttaacgc cgcggatcgt ctttactgca accgatgcgg
      721 atgtgattaa aacgtatgtc aggttggggc tgggcgttgg cgtcattgcc agcatggcgg
      781 tcgatccgct taccgatcct gatttagtgc ggattgacgc gcacgatatt tttagccaca
      841 gcaccacaaa aattggtttt cgccgtagta cttttttacg cagctatatg tatgatttta
      901 tccagcgttt tgcgccacat ctgacgcgtg atgtggtgga tacggcggtg gcgttgcgtt
      961 ctaatgaaga aattgaagcg atgtttcagg atataaagct gcctgaaaag taatatcacc
     1021 gtgggtttgt gtcgtagtgg catggcagac aaagccgcct tttgcaatat ccctcgaagt
     1081 attacgggta atgatcagca aaatagtgtt gaattacccg tcccgccagt ttctttttcc
     1141 aaatagttat cttgagtcaa aagattgatt tattcactgg caacgattcg taaattgact
     1201 ggatttttga ctaaagttta tttaggattt gtctcatctg atgattaatt gtaccgattg
     1261 tttggtgctg aaatgataag tgataccgat agcatgaggt tagtaatgcc ttctgaaaac
     1321 caggaaccgc gccgcgaccc tgagctcaaa cgtaaagcat ggctggcggt ttttgtgggt
     1381 tctgcgttgt tctgggtagt ggtagcgctt gttatctggc attggtgggg ctaagtgagc
     1441 attacgtcgg aacgcgagcg cgtggtcgcg cccccgattc aatctggtga cgatgataac
     1501 accccggata cgaccgtttt tcggtctgtt ccgcaacact ggacgctcac accgcagcag
     1561 cgggcattta ttgatgcttt tgctgacgag gtgtcacaaa aataatattc gtctttttat
     1621 tggcgttact gttttattaa cgctgtctta ttacaccgca gcaaccgtgt gctgagcgct
     1681 tctcagtatt gattaaacac agttggtgtt gcctatgtta acgtcaaata taaagtattg
     1741 gtcatggact ggcgcgttta tattatcgct actgttctgg gccgagttaa tctggattgc
     1801 cgtctaatct cgtcaaagcc cgataatgcg ttatttatcg ggctttttca tcttcgttcc
     1861 tcgcctgtta ggtttctcct cttttagcaa tttgggttgt tatcaaaacg ttacattttg
     1921 tttgtgttat ctttaataca accctgtgga gaatcagggt aacgcaaccc tgtcattaaa
     1981 ggaggagcta tgtcgtcaac cctacgagaa gccagtaagg atacattgca ggccaaagat
     2041 aaaacgtatc attactacag tctgccgctg gctgccaaat ccctgggcga tatcgcccgt
     2101 ttgcccaaat cacttaaagt gttactggaa aacctgttgc gctggcagga cggcgaatct
     2161 gtgactgatg aagatattca ggcgctggcc ggttggctta aaaatgccca tgccgatcgt
     2221 gaaattgctt ggcggcccgc ccgtgtcctg atgcaggact ttaccggcgt gcctgccgtt
     2281 gtcgacctgg cggcgatgcg tgaagccgtt aaacgcctcg gcggcgatac gtcgaaagtg
     2341 aacccgttat cgccggttga tctggttatt gaccactctg tgacggtcga tcatttcggc
     2401 gatgatgatg cgtttgaaga aaacgtgcgg ctggaaatgg aacgtaacca tgagcgttat
     2461 atgttcctga aatggggaaa gcaggcattc agccgtttca gcgtggtgcc gcccggcacc
     2521 ggcatttgcc atcaggttaa cctggaatac ctgggtaaag ccatctggag cgaattacag
     2581 gacggggagt ggattgctta cccggactcg ctggtgggga ctgactccca tacgaccatg
     2641 attaatggtc tgggcgtatt ggggtggggc gtgggtggta ttgaagcgga agcggcgatg
     2701 cttggtcagc ccgtgtcgat gcttatcccg gatgtcgtcg gctttaagtt aaccggtaaa
     2761 cttcgggagg ggatcactgc cactgacctg gtgctaaccg tcacgcaaat gctgcgtaag
     2821 catggcgtcg tgggtaaatt tgttgaattt tatggtgacg gtctggattc gctgccgttg
     2881 gcggatcgcg cgactatcgc taatatgtcg ccggaatatg gcgccacctg tggtttcttc
     2941 cccattgacg ccatcacctt ggaatatatg cgattaagcg gacgtagcga cgatctgatc
     3001 gagctggttg aaacctacgc gaaggcgcag ggaatgtggc gtaatcccgg tgacgaaccg
     3061 gtatttacca gtacgctgga actggatatg ggcgatgtcg aggccagcct ggccgggccg
     3121 aaacgcccgc aggatcgcgt ggcgttaggc gatgtgccga aagcctttgc cgccagcgcc
     3181 gagctggagc tgaataccgc gcaaagagat cgccagccgg ttgactatac gatgaacgga
     3241 cagccatatc agcttccgga tggcgctgtc gtcattgccg ccatcacctc ctgtacgaat
     3301 acctcgaatc ccagcgtgct gatggcggcg ggattactgg cgaaaaaggc agtaacgctg
     3361 gggttgaagc gtcaaccgtg ggtcaaggct tctctggcgc cggggtcaaa agtggtatct
     3421 gactatctgg cgcaggccaa acttacgcct tatctggatg agctcggttt taacctggtc
     3481 ggctatggct gtacgacctg tatcgggaac tccggtccgt tgccggagcc tattgagacc
     3541 gcgattaaaa aaggcgatct gacggtaggg gccgtgcttt ccggtaaccg aaattttgaa
     3601 gggcgtatcc atccgctggt gaaaacgaac tggctggtgt cgccgccgct ggtggtcgcg
     3661 tatgcgctgg ccggaaacat gaatattaac ctcgcgacag acccgctggg gtacgatcgt
     3721 aaaggcgatc cggtatacct gaaggatatc tggccttcgg cgcaggaaat tgcccgcgcc
     3781 gttgaactgg tatcatcgga tatgttccgt aaagagtatg cggaagtgtt tgagggcacg
     3841 gaagaatgga aatcgattca ggttgaatcg tccgatacct acggctggca gtcggattca
     3901 acctatatcc gcctgtcgcc tttctttgat gaaatgcagg cccagcctgc acccgtcaaa
     3961 gatatccacg gcgcgcgtat cctggcgatg ctgggcgatt cggtgacgac cgaccatatt
     4021 tccccggccg gcagtatcaa gccggacagt cccgccggac gctatctgca aaaccacggc
     4081 gttgagcgga aggattttaa ctcctatgga tcacggcgcg gcaaccatga agtgatgatg
     4141 cgcggtacgt tcgccaatat tcgtattcgc aacgaaatgc tgcccggcgt cgaaggtggg
     4201 atgacgcggc atttgccggg tacggaagcg atgtcgattt atgatgccgc gatgctctac
     4261 cagcaggaaa aaacgccgct ggcggtaatt gccgggaaag agtatgggtc gggatcgagc
     4321 cgtgactggg cggcaaaagg tccgcggctg ttaggtattc gcgtggtgat cgccgagtcg
     4381 ttcgaacgta tccatcgctc aagcctgatt gggatgggga tcctgccgct ggagtttcca
     4441 cagggcgtaa cgcgtaaaac gctgggactg accggggaag aggtgattga tatcgcggat
     4501 ctgcaaaatc tgcgccctgg cgcgaccatt ccggttatgt taacgagagc ggacggcagc
     4561 aaagaaacgg tgccttgtcg ctgtcgcatt gataccgcca ccgagctgac ttactaccag
     4621 aatgacggca tattgcacta tgtcattaga aatatgctga actaaagccg tttatcgggc
     4681 ctgccgtaaa caggcaggcc cgcgctttaa taccggtggc ttacttgctt agcaggtggc
     4741 ccattttggc cgctttagta tcgagataat gctcattatt tggattacga cccacaatga
     4801 gcggaacgcg ttccacgata ttaattcccg cctcggtcag tatttcgact ttcttcggat
     4861 tattggtcag taggcgaact tcatccacgc cgagtaattt gaacatatcc gcgcacaggg
     4921 tgaaatcacg ctcatcggcg gcaaagccga gctgatgatt ggcctccacc gtgtcatagc
     4981 cttgatcctg taacgcataa gcgcgaattt tattaagcag gccgatattg cggccttcct
     5041 gacggtggta aatcagaata ccgcgtcctt cttccgcaat atgcgtcagc gcggcttcca
     5101 gttgaaaacc acaatcacag cgcagactaa aaagcgcgtc cccggtaaga cattcggaat
     5161 gaacgcgagc cagtactggc gttttacctg aaatatcgcc aaaaaccagc gcggcatggt
     5221 cgtgtccggt tgccagttct tcaaatccca ccatcagaaa gtcacccaat ggggttggca
     5281 gtttggcttc tgccacacgt ttaagctgca tgtatttctc cagattatgc tgacgcctgc
     5341 ggtgtcgtcg cctgttggcc tgtatcccgc tattttgcca taaggcggcg gtcatcacct
     5401 aatcactacc acgtaattgc tcaggaatgg cacaaatttg tcaattttcc agtccggcga
     5461 gaattttcag ttatgattgt gatacttact tataaaagga gcatccatgc tttcaattgc
     5521 gaggcgcacc gcggcaggcg ccgccctgtt gcttatcatg ccgcttgccg tatgggtatc
     5581 aggctggcag tggcagccag gacatcaggt ctggtggcta aaaacgctat tctggataac
     5641 ggaaaccgtg accaaaccct ggggcgttat cacgcatgtg attctttgtg gatggttctt
     5701 atggtgcctg cgatttcgcc tgcgcgccgc cattatgctg tttgcgattc tcggtggggc
     5761 gattatcgtc gggcagggcg tgaagtcatg ggtaaaggag cgcgtacagg agccgcggcc
     5821 atttgtggtc tggcttgaaa aaacgcacca tattcccgtc gatgagttct acactttaaa
     5881 gcgtacagaa cgcggacatt tagtgaaaga gcagttggcc gggcaacaga acatccccgt
     5941 tttcctgcgt cagcactggc aaaaagagac gggctttgcg tttccctccg gacacaccat
     6001 gtttgcagcg agctgggcgc ttttggccgt gggtctgtta tggccgcgca gacggacttt
     6061 caccatcgcg tttttgttag tctgggcgac cggcgtaatg ggcagccgtt tgcttctggg
     6121 aatgcactgg ccgcgagatt tagtggtcgc cacgctcatc tcctggctat tagttaccct
     6181 ggcgacctgg ctggcgcagc gaatttgcgg gccgcttatg ccgcctcgcg aagaagcgca
     6241 agaaattgct gaacgcgagc aggaaagctg acaacggttg attttctgac tattgccctt
     6301 aaatcatctg atggtgggcg catttccatt tcgcgcgagg cgggaaaatg gtaatttaga
     6361 aggctggatg cggtaagttg gacacgattt attcgcgcaa accacataac gggaagtaat
     6421 gtgaaatatt tactcatttt cttactggta ttggcgattt ttgttatttc ggtgacgctg
     6481 ggcgcgcaga atgatcaaca ggtgacgttt aactacctgc tggcgcaagg ggagtatcgt
     6541 atctccacgt tgcttgctgt gctgttcgcc gtcggttttg cgattggctg gctgatttgc
     6601 ggcctgttct ggctgcgggt ccgcgtttcc cttgcccgcg ctgaacgtaa aattaaacga
     6661 ctggaaaaca agctctcgcc agcaaccgac gttgcggtcc ctgccgattc gtcggttgta
     6721 aaggaataat catttatgtt ggagttgtta tttctgctgt tgcctgtagc cgctgcctat
     6781 gggtggtata tgggtcgcag aagtgcgcaa caaacaaaac aggatgaagc taaccgcctg
     6841 tcgcgcgatt atgtcgcagg ggttaacttc ctgctgagta accaacaaga taaagcggtg
     6901 gatctgttcc tcgatatgct taaagaggat accggcaccg ttgaggctca tctcactctc
     6961 ggtaatttgt ttcgctctcg cggcgaagtc gatcgcgcca ttcgtattca tcaaacgctc
     7021 atggaaagcg cttcattgac ctatgaacag cgtttactgg ctgttcagca actggggcgc
     7081 gactatatgg ccgccggttt atatgaccgc gcggaagata tgtttaacca acttaccgac
     7141 gaaacggaat ttcgcgtagg cgcgttacag cagctcttgc aaatctatca gctaaccagc
     7201 gactggcaaa aggcgatcga agtagcagaa cggctggtga aactgggcaa agataaacag
     7261 cgtatcgaaa tcgcccactt ttactgtgag ttagcgttac agcagatggg caacgacgac
     7321 atggatcgcg cgatggcgtt gctgaaaaaa ggtgccgccg cagataaaaa tagcgcccgg
     7381 gtgtctatca tgatggggcg cgtttatatg gcgagagggg attacgccaa agcggtcgaa
     7441 agcctgcaac gtgtgatcgt tcaggataaa gagctggtca gcgaaacgct ggagatgttg
     7501 caaacctgtt atcaacagct cggtaaaaat gccgagtggg cggagttttt acgtcgcgcc
     7561 gttgaggaga ataccggtgc tggcgctgag ttaatgcttg ccgatattct ggaagcgcgt
     7621 gaaggtagtg acgcagctca agtctatatc acgcgtcagc tacagcgaca tcctaccatg
     7681 cgggtgttcc ataagctgat ggattaccat ctcaatgagg cggaagaagg gcgagcgaaa
     7741 gaaagcctga tggtactgcg tgatatggtt ggcgagcagg tgcgcagtaa accgcggtat
     7801 cgttgtcaga aatgcggttt taccgcctat accttgtact ggcactgtcc gtcctgccgg
     7861 gcatggtcga ccattaaacc tattcgcgga cttgatgggc agtagtatat aaaaaaaacc
     7921 tcactttagt tacaacatac ttaatgacat aagacaagaa acgacgctgg catcggcggc
     7981 cagggcttat caggttgtca atcgaacctg ttaatttccc tgcgccgcag gtagaatgca
     8041 cgccgtttat ccaatttgcg ccacttccgg tgcccatcat caagaaggtc tggtcatgac
     8101 gtttactgct tcatcttctt cctgcgctat tactgaatcg cctgtcgttg tggcgttgga
     8161 ttaccatgaa cgcgataaag ccctggcgtt tgtcgataaa atcgatcctc gcgattgtcg
     8221 cttaaaagtg ggcaaagaga tgttcacgct gtttggtcca caactcgttc gggatctcca
     8281 gcaacgtggg tttgatgtct ttcttgatct aaaatttcat gatattccca acaccacggc
     8341 ccgggcagtc gccgcagcgg cagacctggg cgtttggatg gtaaacgttc acgcgtctgg
     8401 tggggcgaga atgatggccg cagcgcgcga cgcgctggcg ccattcagta aagatgcgcc
     8461 gttgctcatt gccgtgaccg tgttgaccag tatgggaacc agcgatctac acgatctggg
     8521 cgtgacgttg tcaccggcgg aacatgcgga gcggctggcg cgcctgacgc agcaatgcgg
     8581 gctggatggc gtggtctgtt ccgctcagga agctgtcaga tttaaacagg cctttggcgc
     8641 tgcatttaag ctggtgacgc cgggcattcg gcccgcaggc agcgaggcag gcgaccagcg
     8701 acgcattatg acgcccgaac aggcattatc cgctggcgtc gactatatgg tgattggccg
     8761 cccggttacg caatcggtag atccggcgca aacgctgaag gatattaacg cgtcactgaa
     8821 acgggaggca taatgagcga ttccaatagt cgtctggttt attcaacaca gacggggcgc
     8881 attgaagaac ctaaaacggc gccggttcgt cccaaagggg atggtatcgt tcgcattcag
     8941 cgtcaaacca gtggccgtaa gggtaaaggc gtatgtttga ttaccggtat cgagatgaat
     9001 gatgcggaat taaccaaact ggcggctgaa ctgaagaaaa aatgcggctg tggcggggca
     9061 gtaaaagaag ggattattga aattcagggt gataaacgcg acttgataaa atcattgctg
     9121 gaagctaaag gaatgaaagt aaaattagct ggcggctaat gaaaacgcca cggttgtaaa
     9181 ttgccgtggc gtaaaagtca actttgtcta tttttgtaat ccagacctga aaagaataaa
     9241 cgtattattt tgagccgttc aatatttaaa cgtctggatt attttccaac ctggtgacca
     9301 atcacgccgc cgaccgccgc gccgcccagg gtgcctaatg tactgccgtc cgttaacact
     9361 gcgccgccta acgcccccgc acctgcgcca atagccgtgt tgcgatcgcg cttggaccag
//
LOCUS       DAJVBX010000183         9263 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.183, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000183 DAJVBX010000000
VERSION     DAJVBX010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 9263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9263
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.183"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            264..575
                     /locus_tag="OPV72_003665"
     CDS             264..575
                     /locus_tag="OPV72_003665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000107428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915856.1"
                     /translation="MSTREDNATRSMGGKLALWVFYTFCGYFIWAMARCVWLMSAIQT
                     EPVLGPISTPGSATEKWLNALSLGVVWLILGSIAWYTRPRKNRGYPADTQPETRKHAR
                     M"
     gene            655..1350
                     /locus_tag="OPV72_003666"
     CDS             655..1350
                     /locus_tag="OPV72_003666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HCR9915857.1"
                     /translation="MDSGYWQSQFEDWLRHHHQEQDAAHDIFHFRRVWATAQTLGENS
                     PVDWLVVLSACYFHDIVSLAKNHPQRHRSSILAAAETRRIFLRDFPDFPAEKLAGICH
                     AIEAHSFSAKIAPTTPEAKIVQDADRLEALGAIGLARVFAVSGALGVALFDADDPFAN
                     RRPLNDKQFALDHFKTKLLKLPLTMQTERGKHLAQRNADFLVSYMAKLSAELKGDYET
                     RDDAVIQMFATYQ"
     gene            1424..2854
                     /locus_tag="OPV72_003667"
     CDS             1424..2854
                     /locus_tag="OPV72_003667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HCR9915858.1"
                     /translation="MQENISVTHARNLIADDAGSEIQAMLSQLLEIYDVKTLVAHLNG
                     LGEQHWSPAIFKRVMMNAAWHRLSDNELSCLKTELPTPPAHHPHYAFRFIDLFAGIGG
                     IRRGFEAIGGQCVFTSEWNKHAVRTYKANYFCDPLQHRFNEDIRDITLSHREGVSDDE
                     AAEHIRQHIPQHDVLLAGFPCQPFSLAGVSKKNALGRAHGFACETQGTLFFDVVRIID
                     ARRPALFVLENVKNLKSHDQGNTFRIIMQTLDELGYDVADAADNGPDDPKIIDGQHFL
                     PQHRERIVLVGFRRDLNLKTDFTLRNIARCYPPRRPTLAELLEPVVEAKYILTPVLWK
                     YLYRYAKKHQARGNGFGYGMVYPDNPESVARTLSARYYKDGAEILIDRGWDMAKGEVN
                     FDDAGNQQHRPRRLTPRECARLMGFEAPQTYQFRIPVSDTQAYRQFGNSVVVPVFAAV
                     AKLLEPKIHQAVTLRQRETADGGRSR"
     gene            2835..3305
                     /locus_tag="OPV72_003668"
     CDS             2835..3305
                     /locus_tag="OPV72_003668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="very short patch repair endonuclease"
                     /protein_id="HCR9915859.1"
                     /translation="MADVHDKATRSKNMRAIATRDTAIEKRLAGLLSAQGITFHTQDT
                     TLPGKPDFVVNDYDCVIFTHGCFWHHHHCYLFKVPATRTAFWLEKIGKNVERDERDIQ
                     RLQALGWRVLIVWECALRGRAKLSDAALAERLEEWICGGGASAQIDTQGIHLLA"
     gene            complement(3294..4214)
                     /gene="yedA"
                     /locus_tag="OPV72_003669"
     CDS             complement(3294..4214)
                     /gene="yedA"
                     /locus_tag="OPV72_003669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="drug/metabolite exporter YedA"
                     /protein_id="HCR9915860.1"
                     /translation="MRFRQLLPLFGALFALYIIWGSTYFVIRIGVESWPPLMMAGVRF
                     LSAGMLLMAFLLLRGEKLPPLRQTINAALIGLLLLAVGNGLVTVAEHQNVPSGIAAVV
                     VATVPLFTLCFSYFFGIKTRKLEWVGIAIGLAGIILLNSGGNLSGNPWGAILILIGSM
                     SWAFGSVYGSRIALPVGMMAGAIEMLAAGVVLLCAAFLSGEKLATLPGLSGFMAVGYL
                     ALFGSIIAINAYMYLIRNVSPALATSYAYVNPVVAVLLGTGLGGERLSPVEWAALGVI
                     VFAVVLVTLGKYLFPARAVITPCKTEDSRQ"
     gene            4384..5301
                     /locus_tag="OPV72_003670"
                     /pseudo
     CDS             4384..5301
                     /locus_tag="OPV72_003670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310723.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF808 domain-containing protein"
     gene            5378..5563
                     /locus_tag="OPV72_003671"
     CDS             5378..5563
                     /locus_tag="OPV72_003671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YodC family protein"
                     /protein_id="HCR9915861.1"
                     /translation="MVFSVSEEVTVKEGGPRMIVTGYSSGMVECRWYDGFGVKREAFH
                     ENELVPGKERRVRDEAR"
     gene            5728..7431
                     /gene="yedQ"
                     /locus_tag="OPV72_003672"
     CDS             5728..7431
                     /gene="yedQ"
                     /locus_tag="OPV72_003672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis regulator YedQ"
                     /protein_id="HCR9915862.1"
                     /translation="MPHETLLDNQGWFKKLARRFGPGHVVNTCFLIVMLFSTLLTWRE
                     VMILKDAYVASQRNHLGSVANVLDRQLQFNMDRLIFLRNGMHEALVAPLAFSALQSAV
                     TQFEQRRVRHFWQLELDKRRTLPLYGVSDQFVARTTLLSRESRDLANELTATLELGYL
                     ARSSAMLTLETMYVSRSGFYLSTLPTAYGSDIVSRYYQYVTQPWFIEQSQRRNPQRGV
                     RWFTSAQPYVADEQKKVTASLPLDHDNYWYGVLAMDIPVASLQQFLRDAAEKDIEGEY
                     QLYDNHLRLLTDSAPEQQTENTLNDRERALLAREIEKDTLGGLRLGTHYVSWERLDHF
                     DGVLLRVHTLREGIQGNFGSISIALTLLWGLFTAMLLISWGVIRHMVKNMFVLQNSPQ
                     WQAWHDPLTRLYNRGALFEKASRLAKRYREARQPFSVIQLDLDYFKSVNDRFGHQAGD
                     RVLSHAAGLIGSTIRAHDIAGRVGGEEFCIVLPGATKAQALQIAERIRQRINDKEILV
                     TKSTTLRISASMGISSAEEYGDYDFEQLQSLADKRLYYAKQSGRNRICASDATQEREK
                     K"
     gene            complement(7410..8225)
                     /locus_tag="OPV72_003673"
     CDS             complement(7410..8225)
                     /locus_tag="OPV72_003673"
                     /EC_number="3.1.3.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-3-phosphoglycerate phosphatase-related
                     protein"
                     /protein_id="HCR9915863.1"
                     /translation="MLSIHDPLLIFTDLDGTLLNSHTFEWQPAAPWLTRLHESGVPVI
                     LCSSKTAAEMLQLQTTLNLQGLPLIAENGAVIQLDVHWEDHPNYPRLIAGISHNEIRL
                     VLHKLREKEQFKFTTFDDVDDQVISEWTGLNRAQSALTRLHEASVSLIWRDSDERMAQ
                     FVARLNDLGLQFVHGARFWHVLDASAGKDQAANWLIEAYRRQWRARPLTLGLGDGPND
                     APLLDVMDYAVVVKGLNREGVHLRNDDPQRVYRSQNEGPDGWREGMDYFFSRS"
     gene            complement(8535..8762)
                     /gene="yodD"
                     /locus_tag="OPV72_003674"
     CDS             complement(8535..8762)
                     /gene="yodD"
                     /locus_tag="OPV72_003674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YodD family peroxide/acid resistance protein"
                     /protein_id="HCR9915864.1"
                     /translation="MKTAKEYSDTAKREVSVDVDALLAAINEISESEVHRSQEDPERV
                     SVDGREYHTWHELAEAFELDIHDFSVTEVNR"
     gene            8891..9085
                     /gene="dsrB"
                     /locus_tag="OPV72_003675"
     CDS             8891..9085
                     /gene="dsrB"
                     /locus_tag="OPV72_003675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001736680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DsrB"
                     /protein_id="HCR9915865.1"
                     /translation="MKVNDRVTVKTDGGPRRPGVVLAVEEFSEGTMYLVSLEDYPLGI
                     WFFNESGHQDGIFVEKAEQD"
     gene            complement(9124..>9263)
                     /gene="rcsA"
                     /locus_tag="OPV72_003676"
     CDS             complement(9124..>9263)
                     /gene="rcsA"
                     /locus_tag="OPV72_003676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310717.1"
                     /note="with RcsB is a positive regulator of capsular
                     polysaccharide synthesis genes; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transcriptional regulator RcsA"
                     /protein_id="HCR9915866.1"
                     /translation="NIKAKTVSSHKGNIKRKIKTHNKQVIYHVVRLTDNVTNGIFANM
                     R"
BASE COUNT         2245 a         2321 c         2541 g         2156 t
ORIGIN      
        1 gctaataaaa taaaacgcta tcgcggtgcg taaaaataag ttgttctggt tatgggttat
       61 tctgcatcag agtgcgattc aattaccatt cccttattta acagcaggtt cagcgccaga
      121 cgcaacatta actgagaata aactatttgt ggaatgaata accagaacag gtggataagg
      181 tattccatgg tcgaaatgtg actaatatca cattataatg taattaatgt catatgactt
      241 acatcacaaa agcggagtaa agtttgagta ccagggagga caacgccacc cgtagcatgg
      301 gcggtaaatt agcgttatgg gttttttata ccttttgcgg ctacttcatc tgggcgatgg
      361 cgcgttgcgt gtggctgatg tccgccatac aaaccgagcc ggttctcggc ccaatcagca
      421 ctcctggcag cgcaacggaa aaatggctta acgcgctttc gctgggcgtc gtctggctta
      481 ttctggggag tattgcctgg tacacccggc ctcgcaaaaa cagggggtat cccgccgaca
      541 ctcagccaga aacgcgcaag cacgcaagga tgtaaagtgg tggcggatat gtcaggatag
      601 cgaaccctgt gctcaggcat gtaataaaaa tggtctgcta taaagagagg gcgtatggac
      661 tcaggatact ggcaatcgca gtttgaagac tggctacgtc accaccacca ggaacaggat
      721 gccgcccatg acatcttcca ttttcgtcgt gtttgggcaa ccgcgcaaac gctcggggaa
      781 aacagtcctg tcgactggct ggtggtgcta tcggcatgtt atttccatga catcgtcagc
      841 ctggcgaaaa atcatccgca gcggcatcgt tcttccattc tggcggcggc agaaacccgg
      901 cgtatttttc tgcgggattt tcctgacttt ccggcagaaa aactggcggg catttgtcat
      961 gctatcgaag cgcatagctt cagcgcaaaa attgcgccta ccacgccaga ggcaaaaatc
     1021 gtacaggatg cagacaggct ggaggcgttg ggcgccattg gtctggcgcg ggtcttcgcg
     1081 gtctccggcg cgctgggcgt cgcgctgttt gatgccgacg atccctttgc caacagacgg
     1141 cctcttaacg ataagcaatt cgcgctcgac cattttaaaa ccaaactgct gaaactgccg
     1201 ctgacgatgc agaccgaacg gggcaagcac ctggcgcagc gtaatgcgga ttttctggtg
     1261 tcgtacatgg cgaaactgag cgctgagctg aaaggcgact atgaaacacg ggatgatgcg
     1321 gtcatccaga tgtttgctac gtatcagtaa cccctgccgc tgaaacgtaa accgcgtcat
     1381 tttatgttag tctgtcggca attatttttg gccggttaaa tgtatgcagg aaaatatttc
     1441 agtaacacac gcccggaacc tcatcgccga cgacgccgga agcgagatcc aggcgatgct
     1501 gagtcaattg ctggaaatct acgatgttaa aacgctggtg gcgcacctta acggcctggg
     1561 cgaacagcac tggagcccgg ccatcttcaa gcgcgtaatg atgaacgcgg catggcatcg
     1621 tttgagcgac aatgaactca gctgtcttaa aacagagttg ccgacgccgc cagcgcatca
     1681 tccacattac gcctttcgtt ttatcgatct cttcgcgggc atcggcggca ttcgccgcgg
     1741 atttgaagcg ataggcggac agtgcgtgtt taccagcgaa tggaataagc acgcggtacg
     1801 gacatataaa gcgaactatt tttgcgatcc gctgcaacat cgctttaatg aagatatccg
     1861 cgatatcaca ttgagccacc gggaaggggt cagcgatgat gaggcggcgg aacacattcg
     1921 ccagcatatt ccgcaacatg atgtcctgct ggcgggcttt ccctgtcagc cattttctct
     1981 ggcgggcgtt tccaagaaaa atgcgctggg ccgcgcccac ggctttgcct gcgagactca
     2041 ggggacgtta ttttttgatg tcgtaagaat tatcgacgcc cgccgccccg cgctgtttgt
     2101 gctggaaaac gtgaaaaacc ttaaaagtca cgaccagggc aacaccttcc gcattattat
     2161 gcaaacgctc gatgaactgg gatatgacgt ggcggatgcc gctgacaatg gcccggacga
     2221 tccgaaaatt atcgacgggc agcactttct tcctcagcat cgggaacgta ttgtgttggt
     2281 gggattccgt cgcgatttaa acctgaaaac cgattttacg ttacgcaata tcgcccgttg
     2341 ttatccaccg cgccgtccga cgctggcaga actgctggag cccgtcgtcg aagccaaata
     2401 tatcctgacg ccggtgctgt ggaaatattt atatcgctac gcgaaaaagc accaggcgcg
     2461 gggaaacggt tttggctatg gcatggttta tcctgacaat ccggaaagtg tggcgcgcac
     2521 gttatctgct cgctactaca aagatggcgc cgaaattctg atcgatcgtg gttgggatat
     2581 ggcgaaaggc gaagtgaatt tcgacgatgc tggcaaccaa caacatcgtc cccgccgact
     2641 cacgccgaga gagtgcgcgc gtttaatggg atttgaggcg ccgcaaacgt accagttcag
     2701 gatacctgtc tcggatacgc aggcctatcg ccagtttggc aactccgtgg tggtgccggt
     2761 atttgccgcg gtagcaaagc tgctggaacc caaaattcac caggcggtga cgctgcgtca
     2821 gagagagacg gcagatggcg gacgttcacg ataaagccac gcgcagtaaa aatatgcgcg
     2881 cgatagcgac ccgcgatacg gcgattgaaa aacgccttgc tggcctgtta agcgcgcagg
     2941 ggattacgtt tcatactcag gacacgacat taccgggcaa gccggacttt gtggtgaatg
     3001 actatgattg tgtgattttt actcacggct gcttttggca tcatcaccac tgttatctat
     3061 tcaaagtacc ggccacgcga acggctttct ggctggaaaa aatcggtaag aacgttgagc
     3121 gcgatgagcg tgatattcag cgtttacagg cgcttggctg gcgggtactg atcgtctggg
     3181 agtgcgcctt gcgcgggcga gcgaaattga gcgacgcggc gttggcggag cgcctggaag
     3241 agtggatctg cggcggcggc gccagcgcgc agatcgacac ccaggggatt catctactgg
     3301 cgtgaatctt ccgttttaca cggtgtgatc accgccctgg cgggaaacag gtacttaccc
     3361 agagtcacta gcactacggc aaacacaatc acgcccagcg cggcccattc aacgggcgat
     3421 aacctctcac cgcctaggcc agtgccaagc aacacggcga caaccggatt cacataggcg
     3481 tagctggtcg ccagcgccgg actgacgttg cgaatcaggt acatataggc attaatggcg
     3541 ataatagaac cgaataacgc caggtagccg acggccataa accccgataa accaggcagc
     3601 gtggcgagct tttcgccgga aagaaacgcc gcgcaaagca ataccacgcc cgccgccagc
     3661 atttcaatcg cgcccgccat catgcccaca ggcagggcga tgcgcgagcc gtaaacggaa
     3721 ccaaatgccc agctcatcga acctatcagg atcaaaatcg cgccccacgg attgccgctt
     3781 aaattaccgc cgctgttcag cagaataatc ccggcaagtc caatggcaat ccccacccat
     3841 tctaatttgc gcgttttaat accaaaaaag tagctaaagc acagcgtaaa tagcgggaca
     3901 gtggcgacca cgacggcagc aatgcccgat ggcacgtttt gatgctccgc caccgtcacc
     3961 agaccgttac ccaccgccag cagcagtagg ccaatcagcg cggcgttgat ggtctggcgc
     4021 agcggcggaa gtttttcgcc gcgcaacagc aaaaacgcca tgagcaacat ccccgccgag
     4081 agaaaacgta cgcctgccat cattagcggc ggccagcttt caacgcctat gcggataaca
     4141 aaataggtag acccccaaat gatgtacaag gcaaaaagcg cgccaaaaag aggtaataac
     4201 tgccggaaac gcataatcac tcacggtgaa ataaaaaggg tgaatatagt aaacgtcaaa
     4261 attattatgc tggcgagcat tataattgtc cttttggaat aaaaaggcgt tgacccgcgc
     4321 cgccggtttc ggcattgcgc gttttgctac atacttaacg tcttagaaga aaagaccgag
     4381 gaaatcattt tggcaggaag tagcttactg acattactcg acgatatcgc cacgctgctg
     4441 gacgatattt cggtaatggg caaattggcc gcgaaaaaaa ccgcaggcgt actgggggac
     4501 gacctgtcgc tcaatgcgca gcaggtgacc ggcgttcgcg ctaatcgcga gctgccagtg
     4561 gtatggagcg tggcgaaagg atcattaatc aacaaggtta ttctggtgcc gttggcgctg
     4621 ttgataagcg catttatccc gtgagccatt acgcctttat taatgttagg cggcgcgttt
     4681 ctctgctttg aaggggtaga aaaagtcctg catacctttg aggcgcgaaa acacaaagaa
     4741 gacctggcgg agcggcaaaa acgtcttgag gcgctggcta cgcaagatcc tttggccttt
     4801 gaaaaagata aagtaaaagg ggcggtccgt accgatttca ttctttccgc tgaaattgtg
     4861 gcaattaccc tggggattgt cgcgcaggca ccgctgctta atcaggtgtt ggtgctggcg
     4921 gggattgcgt tggttgtgac cattggcgtg tatggcctgg tgggtattat tgtcaaactg
     4981 gatgatatgg ggtactggct ggcggaaaag cgtagcgtgc tggcgcaggg cgtcggtaaa
     5041 ggattactga ttatcgcgcc ctggttaatg aaagcattat ccattgtcgg tacgctggcg
     5101 atgtttctgg ttggcggcgg aattgtcgta cacggtattg cgccgctaca ccatgccatt
     5161 gaacattttg cgcagcagca gggggctttc atggcgcata cgatccctgc ggggctgaat
     5221 ctggtgctcg gctttattat cggcgccatt gtggtggcgc tggtgaaagg tgtggcgaaa
     5281 attcgcggtg tttcgcactg attttctaca atgaattatg caaaattgtc catcctcgtc
     5341 taaggtgaaa acgtttcatc tgatacagga ggcaggtatg gtcttttctg tcagtgagga
     5401 agttaccgtg aaagagggtg gaccccggat gatcgtcacc ggttattcca gcggaatggt
     5461 agagtgtcgc tggtatgatg gttttggcgt aaagcgggag gcattccatg agaatgagct
     5521 cgtgccaggc aaggaaaggc gcgtgcggga tgaagcccga tgacaaaacg cccggttaat
     5581 gccgggcgtt ttgctgtgga gaaaaagagt cgtcgcgctg cgacatgctg ctacctggtt
     5641 atgccaggat tgagtggtat cccttgatga ggtctggcta ccgtaagcca tcagggggcg
     5701 ttgtatcaat aaccaggagt taccagggtg ccgcacgaaa cactgttaga caatcaaggc
     5761 tggtttaaaa agctggcgcg gcgttttggt cccggtcatg tcgtcaacac ctgttttctg
     5821 atcgtgatgc tgttctcgac gctacttacc tggcgggaag ttatgatact gaaagacgcg
     5881 tatgtcgcca gtcagcgcaa tcatctgggg agcgtcgcga atgtccttga ccgccaactg
     5941 caattcaaca tggacaggtt gatcttttta cgcaacggta tgcatgaagc gctggtggcg
     6001 ccgctggctt tttccgcatt gcaaagcgcg gtgacgcagt ttgagcaacg acgcgtcaga
     6061 catttctggc aactggagtt ggataaacgg cggacattgc cgttatatgg cgtttccgat
     6121 caatttgtcg cccggacgac gcttctttcg cgggagagtc gtgacctggc aaatgaatta
     6181 accgccacgc tggagttagg gtatctggcg cgctcatccg ccatgctgac gctggagacg
     6241 atgtatgttt ctcgctcagg gttttacctc tcaactctcc ctacggcgta cggtagcgat
     6301 attgtttccc gttactatca gtacgtgacc cagccctggt ttatcgagca aagccaacgg
     6361 cgtaatccac agcgcggcgt gcggtggttt acctccgcac agccctatgt tgctgacgag
     6421 cagaaaaaag tgacagccag tctaccgctg gatcacgata attactggta tggcgtactg
     6481 gcaatggata ttcccgtcgc gtcattacag cagtttctgc gcgatgcggc cgaaaaggat
     6541 attgaagggg aatatcagct atacgataac catctccgtt tgttgacgga ctccgcgccg
     6601 gaacaacaaa ccgagaatac gttaaatgac cgtgagcgcg ccttactggc gcgtgaaata
     6661 gaaaaagata ccctgggcgg gctgcgttta ggaacgcatt atgtaagctg ggagcggctg
     6721 gatcattttg atggcgtcct gctgcgcgtg catacattac gtgaaggtat acaagggaat
     6781 tttggcagta ttagtatcgc gctgacgctg ttatgggggc tttttacggc gatgctgttg
     6841 atctcctggg gcgttattcg acatatggtc aaaaatatgt ttgttctgca aaattcgccg
     6901 caatggcagg catggcacga tccgctgacc cggctatata accgtggcgc gctgtttgaa
     6961 aaagcgtcca ggctggcaaa gcgctatcgg gaagcccgcc agccattttc tgtgatacag
     7021 ctggatttag attattttaa aagcgttaac gatcgctttg gccatcaggc aggcgatcgc
     7081 gtgttgtccc atgccgctgg gctcattggc agcaccattc gagcgcacga catcgccgga
     7141 cgggtagggg gcgaagagtt ttgtatcgtg ctgcccggcg cgacgaaagc gcaggcgctg
     7201 cagattgccg aacgcatacg ccagcgcatt aatgacaaag agattctggt gacgaaaagc
     7261 acgacgcttc gtatcagcgc gtcaatgggg atcagtagcg cggaggaata cggcgactat
     7321 gattttgagc agttgcagtc gctggccgac aaacggcttt attacgccaa acagtccgga
     7381 cgtaaccgta tttgcgccag cgacgcgact caggagcggg aaaagaaata gtccattcct
     7441 tcgcgccagc catccggccc ttcgttctgg ctacggtaga cgcgctgagg atcgtcgtta
     7501 cgcaaatgta caccctcccg gtttagccct ttaacgacaa ccgcataatc catcacatcc
     7561 agtaagggcg catcattggg gccgtctcct agccccaacg tcagaggacg cgcgcgccac
     7621 tgccgacgat atgcttcaat tagccagttg gcagcctgat ctttaccggc ggaggcgtcc
     7681 agcacatgcc agaaacgggc gccatggaca aattgcagtc ccaggtcatt taaacgggcg
     7741 acaaactgcg ccatgcgttc atcgctatcg cgccagatca gcgacaccga cgcttcatgc
     7801 agacgggtta gggcagactg tgcccggttt aggcccgtcc attcgcttat cacctgatcg
     7861 tcaacgtcat caaacgtggt gaacttaaac tgttcctttt cacgcaactt atgcaggacg
     7921 aggcggattt cgttgtgaga aataccggct atcaggcggg gatagttggg atggtcttcc
     7981 caatgaacgt ccagttggat caccgcgccg ttttccgcaa tcagcggcag tccctgtaga
     8041 tttaacgtcg tctggagctg gagcatttca gccgcggttt tactgctaca gaggatcaca
     8101 ggcacgccgc tttcatgcag gcgtgtaagc cagggggccg cgggctgcca ctcaaaagtg
     8161 tggctgttca gcaatgtgcc gtccagatcg gtaaaaatca gcaaggggtc atggattgag
     8221 agcatttttt cctcattttc cgttgcaacg gcgggcttat ttccaggaaa aatcctaaag
     8281 cacatccgaa agaagtcgaa cgctaactgg aaccgatccc gtcgcttcca ggcagcacat
     8341 gcgttgtcac acttttgcta ccgaactatt agcgcgctta atcattcatg taaaaaatat
     8401 ttacttgtca tgcaaaaaaa ttgcagataa agtaaatctc acatcagatt tcctggtgta
     8461 acgaattttc aagtgcttct tgcataagca agtttgatcc cgacccgtag ggccgggatt
     8521 tttttcggcc atttttaacg gtttacttct gttacactaa aatcatgaat atccagctcg
     8581 aatgcttcag ctaattcatg ccatgtatga tattcccgtc cgtctacgct cacccgctca
     8641 ggatcttcct ggctacggtg aacctcgctt tcgctgattt cattgatggc cgccagtagc
     8701 gcatctacat cgacgctcac ttcgcgcttg gccgtatcac tgtactcttt tgccgttttc
     8761 atcttcacta cctcacgggt tcctgacagc ctaagtatag accgttgaga aaaccagcaa
     8821 acacgccggc aaggcgctgt cagacgcaga aaattgttct acactggcac aaagcgacag
     8881 gaggaaaatg atgaaggtga atgatcgggt aaccgttaaa acggacggcg gtccccgccg
     8941 accgggcgtg gtactggcag tggaagaatt tagtgaaggc acaatgtacc tggtttcgct
     9001 ggaggattac ccgctcggca tctggttctt caatgagtca ggtcaccagg atggtatttt
     9061 tgtcgagaag gcggagcagg actaattgag ccggactgga ggtacattgc cagtccggat
     9121 gtctcagcgc atgttagcaa aaatgccgtt agtgacgtta tctgtcagcc gcactacgtg
     9181 atagatcact tgtttattat gcgtttttat ctttcttttt atattcccct tatgggagga
     9241 tactgttttt gctttaatat tca
//
LOCUS       DAJVBX010000184         9256 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.184, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000184 DAJVBX010000000
VERSION     DAJVBX010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 9256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9256
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.184"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..538
                     /locus_tag="OPV72_003677"
     CDS             <1..538
                     /locus_tag="OPV72_003677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016529756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCR9915867.1"
                     /translation="NDQNTDLQRNALSCAGCERIFEDKISGTKSDRPGLKKLLRTLSA
                     GDTLVVWKLDRLGRSMRHLVTLIEELRQRGVNFRSLTDSIDTSTPMGRFFFHVMGALA
                     EMERELIVERTRAGLAAARAKGRVGGRRPKLTSEQWAQIGRLLEAGESRQRIALIFDV
                     GVSTIYRKFPANKNNKSP"
     gene            681..1853
                     /locus_tag="OPV72_003678"
     CDS             681..1853
                     /locus_tag="OPV72_003678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath protein"
                     /protein_id="HCR9915868.1"
                     /translation="MAQDYHHGVRVVEVNEGTRSITTVSTAIVGMVCTGDDADAKMFP
                     LNKPVLITDVLTASGKAGESGTLARSLDAIADQAKPVTVVVRVPQGETEEETTTNIIG
                     AVTAEGKKTGMKALLSAQSQLGVKPRILGVPGHDTKAVATELLSVAQSLRGFAYLSAY
                     GCKTVQEAITYRENFSQREGMLIWPDFTGWDTVLNAEATAYATARALGLRAKIDEQTG
                     WHKSLSNVGVNGVTGISADVFWDLQDPATDAGLLNQNDVTTLVRKDGFRFWGSRCLSD
                     DPLFAFENYTRTAQVLTDTMAEAHMWAVDKPLNPSLARDIIEGIRAKMRSLVSQGYLI
                     GGDCWLDESVNDKDTLKAGKLTIDYDYTPVPPLENLMLRQRITDQYLVNFSSQVSA"
     gene            1863..2378
                     /locus_tag="OPV72_003679"
     CDS             1863..2378
                     /locus_tag="OPV72_003679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail tube protein"
                     /protein_id="HCR9915869.1"
                     /translation="MALPRKLKHLNLFNDGNNWQGIVESLTLPKFTRKYEKYRGGGMP
                     GAVDVDLGLDDGALDTEFSIGGTELLLFKQMGKATVDGIQLRFTGSIQRDDTGEVQAV
                     ELVVRGRHKEVDSGEWKTGESNTTKVTSTNSYAKLTINGEVLYEVDLINMVEIVDGVD
                     LMEAHRNALGL"
     gene            2433..2735
                     /locus_tag="OPV72_003680"
     CDS             2433..2735
                     /locus_tag="OPV72_003680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly protein"
                     /protein_id="HCR9915870.1"
                     /translation="MSDKKTEKTIQLDTPIKRGKTEITEIVLRKPQSGALRGTRLQAI
                     MDMDVNAMMTVIPRISSPALTAQEIAEMDPADLTAMSVEVVTFLLKKSVLAGLPTA"
     gene            2750..2869
                     /locus_tag="OPV72_003681"
     CDS             2750..2869
                     /locus_tag="OPV72_003681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GpE family phage tail protein"
                     /protein_id="HCR9915871.1"
                     /translation="MADIATIFHWPPSVTDVMPLTEVLEWRYKAIQRSGANDE"
     gene            2862..5939
                     /locus_tag="OPV72_003682"
     CDS             2862..5939
                     /locus_tag="OPV72_003682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001282780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HCR9915872.1"
                     /translation="MSDNNLRLQVILNAVDKLTRPFRSAQASSRELAAAVKKSRDAIK
                     QLDQAGSSLDSFRKLQAENQKLGDRLNYARQRANLLSQELGAMGPPSQRQVVALGRQR
                     LAVQRLEERQKKLQQQTALVRAELYRAGISAKDDAGATARLARETSRYNQELSKQEAR
                     LKRLGEAQRRMNVARASYARSLEVRDRIAGAGATTTAAGLAMGTPVMAAVKSYTSMED
                     AMKGVAKQVNGLRDDNGNRTARFYEMQDAIKAASEQLPMENGAVDFAALVEGGARMNV
                     ANPDDSWEDQKRDLLAFASTAAKAATAFELPADELSESLGKIAQLYKIPTRNIEQLGD
                     ALNYLDDNAMSKGADIIDVMQRLGGVADRLDYRKAAALGSTFLTLGAAPEVAASAANA
                     IVRELSIATMQSKSFFEGMNLLKLNPEVIEKQMTKDAMGTIQRVLEKVNALPQDKRLS
                     AMTMLFGKEFGDDAAKLANNLPELQRQLKLTAGNDALGSMQKESDINKDSLSAQWLLV
                     KTGAQNTFSSLGETLRQPLMDILYMVKSVTGASRRWVEANPELTGTLMKVAAVVAAVT
                     VGLGTLAVALAAVLGPLAVIRLGFSVLGIKTLPSVTAAVTRTSSALSWLAGAPLALLR
                     RGLASSGNAAGLLTAPLSSLRRTASLTGNVLKTVAGAPVALLRSGLSGLRAVAVMFMN
                     PLAALRGGLAAAGAVLRVLASGPLAMLRIALYAVSGLLGALLSPIGLVVTALAGVALV
                     VWKYWQPITAFLGGVVEGFKAAAGPISAAFEPLKPVFQWIGDKVQALWGWFTDLLTPV
                     KSTSAELQSAAAMGRRFGEALAEGLNMVMHPLDSLKSGVSWLLEKLGIVSKEAAKAKL
                     PESVTRQQPATVNADGKVMMPSGGFPSWGYGFAGMYDSGGYIPRGQFGIVGENGPEIV
                     NGPANVTSRRNTAALAAVVAGMMGVAAAPAELPPLHPLAFPAKGGEAMVSRAATVSPV
                     QRIEAPTQIIIQTQPGQSVQDIAREVARQLDERERRLKAKARSNYSDQGGYDA"
     gene            5936..6421
                     /locus_tag="OPV72_003683"
     CDS             5936..6421
                     /locus_tag="OPV72_003683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCR9915873.1"
                     /translation="MMMVLGLYVFMLRTVPYQELLYQRSWRHAANSRVNRRPSTQFLG
                     PDNDMLTLSGVLMPEITGGRLSLLALEQMAEQGKAWPLIEGSGTIYGMYVIEGLNQTK
                     TEFFRDGMPRRIEFTLSLKRVDESLSDMFGDLSAQLNNLQDTVTSALSDISKTVGGLL
                     S"
     gene            6418..7518
                     /locus_tag="OPV72_003684"
     CDS             6418..7518
                     /locus_tag="OPV72_003684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage late control D family protein"
                     /protein_id="HCR9915874.1"
                     /translation="MNFSSELLNKGNKTPAFSISIEGKDITTVLDNRLMSLTLTDNRG
                     FEADQLDLELDDADGKIVLPRRGAVITLALGWKGQPLFPKGAFTVDEIEHTGAPDRLT
                     IRARSADFRETLNTRREKSWHKTTVGEVVKEIAARHKLKMALGEDLSDKPVEHIDQTN
                     ESDGSFLMRLARQYGAIASVKNGNLLFIRQGQGKSASGKPLPVITITRKDGDSHRFTL
                     ADRGAYTGVIASWLHTREPAKKESTTVKRKRRTKKQKKEPEAKQGDYLVGTDENVLVL
                     NRTYANRSNAERAAKMQWERLQRGVASFSLQLAEGRADLYTEMPVKVSGFKQPIDDAE
                     WTITTLTHTVSPDNGFTTSLELEVRIDDFEME"
     gene            7609..7827
                     /locus_tag="OPV72_003685"
     CDS             7609..7827
                     /locus_tag="OPV72_003685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001504085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ogr/Delta-like zinc finger family protein"
                     /protein_id="HCR9915875.1"
                     /translation="MMICPLCGSAAHTRSSFQVSSLTKERYNQCQNINCSHTFVTHET
                     FVRSIATPKESNPVQPHPMKSGQVALSL"
     gene            7917..9239
                     /locus_tag="OPV72_003686"
                     /pseudo
     CDS             7917..9239
                     /locus_tag="OPV72_003686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462790.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
BASE COUNT         2256 a         2307 c         2737 g         1956 t
ORIGIN      
        1 aaatgaccag aacaccgatt tgcaacgcaa tgcactgagc tgtgcgggat gtgagcggat
       61 ttttgaggat aaaatcagtg gcaccaagtc cgacagaccg gggctgaaaa agctgctcag
      121 gacactatcg gcaggagaca cgctggttgt ctggaagctg gacagactgg ggcgcagtat
      181 gcggcatctt gttacgctga tagaagagct gcgccagcgt ggcgtgaatt tccgaagcct
      241 gactgacagt attgatacca gcaccccaat gggccgtttc ttttttcatg tcatgggtgc
      301 cctggctgaa atggaacgcg aactgatagt tgaacgtacc agggcggggc tggctgcagc
      361 tcgtgctaaa ggcagagtag gtggacgccg tcctaagttg accagcgaac agtgggcaca
      421 gattgggcgt ttactcgagg ccggagaatc aagacagcgt attgcactga tttttgatgt
      481 aggcgtttct accatttatc gaaaatttcc ggcaaataag aacaataaat ctccctgaat
      541 cagctttatt ttgattatcc ctgaaagcag acaaataccg tcattttgtg tgaataacgg
      601 tacaactgcg cttagctgtt tgtcaggcac aatcacttca acatagggcg aagcctaatc
      661 caatcaggag gttcgccact atggctcagg attaccacca cggggtgcgc gttgttgaag
      721 tcaacgaagg cacccgatcc attaccacgg tgagcaccgc catcgtgggt atggtctgca
      781 cgggcgatga tgccgatgca aaaatgtttc ctcttaataa acccgtgctg atcactgatg
      841 tgctgactgc cagcggtaaa gcgggtgagt caggcacgct ggcccgttcg ctggatgcca
      901 tcgctgacca ggcaaaaccc gtgaccgttg ttgtgcgtgt gccgcagggt gaaacggaag
      961 aagaaaccac gaccaatatc atcggcgcag tgaccgctga aggtaaaaaa acaggcatga
     1021 aagccctgtt atctgcccag tcacagcttg gcgttaaacc gcgcattctc ggcgtgccag
     1081 gccacgacac caaggcggta gctactgagt tgctgagcgt ggcgcaaagc ctgcgtggat
     1141 ttgcttacct gtcagcgtat ggctgcaaga cggtacagga ggcgatcact taccgtgaaa
     1201 acttcagcca gcgcgaaggg atgctgatct ggcctgactt tactggctgg gacactgtgc
     1261 tgaatgccga agcaacggca tatgccaccg cccgtgcgct tggtctgcgc gccaaaattg
     1321 acgagcagac cggatggcac aaaagcctgt ccaacgtggg cgtgaacggt gtcaccggaa
     1381 tttctgctga tgtgttctgg gatctgcagg acccggcaac cgatgcggga ctgctgaacc
     1441 agaacgacgt caccacgctt gtgcgtaaag acggtttccg cttctggggt tcccgctgcc
     1501 tgagtgatga cccgctcttt gccttcgaaa actacacccg cacggcgcag gtgctgacgg
     1561 acacgatggc agaagcgcac atgtgggcgg tggataaacc gctgaatccg tcgctggccc
     1621 gcgacattat cgagggtatc cgcgccaaaa tgcgcagcct ggtcagtcag ggctatctca
     1681 ttggtggtga ttgctggctg gatgagtcgg tgaacgacaa agacacgctg aaagccggaa
     1741 aactcaccat cgactacgac tacacgccag tgccgccact tgaaaacctg atgctgcgtc
     1801 agcgcatcac cgatcagtac ctggtgaatt tctccagcca ggtcagcgcg taaggggaca
     1861 acatggcttt accacgcaaa ttaaaacacc tgaacctgtt taatgacggg aacaactggc
     1921 aggggatcgt tgagtcgctg acgctgccga aatttacccg caaatatgag aagtatcgcg
     1981 gcggcggaat gccgggtgca gtggatgtgg atctggggct ggatgacggc gcactggata
     2041 cggaattttc cattggtggt actgagctgc tgctgtttaa gcagatgggc aaagccacgg
     2101 tggatggcat ccagctgcgc tttaccggct ctattcagcg tgatgatacc ggggaagtgc
     2161 aggccgtgga gcttgtggtg cgtggacgtc acaaagaagt ggattccggc gagtggaaga
     2221 cgggcgaaag caacaccacc aaagtgacca gtaccaacag ctacgcgaag ctgaccatca
     2281 atggtgaggt gctctatgaa gtggacctga tcaacatggt ggaaattgtg gacggtgtgg
     2341 acctgatgga agcgcaccgt aacgccctcg gcctctgatg tatctgaacg gcgtgggata
     2401 ccgcgccaga acccaattta caggacagca aaatgagcga taagaagact gaaaagacca
     2461 ttcaactgga tactcccatc aagcgcggaa aaacggaaat caccgaaatt gtgctgcgta
     2521 aaccgcagtc cggtgcgctg cgcggtacac gcctgcaggc cattatggat atggatgtga
     2581 acgcgatgat gaccgtgatc ccccgcatct ccagcccggc actgactgca caggaaattg
     2641 cagagatgga cccggcagat ctcactgcca tgtcggttga ggttgtcact tttttgttga
     2701 agaagtcggt gcttgccggt ttaccgacag cctgacggtt gacgatctgg tggcagatat
     2761 cgccaccatt tttcactggc cgccatccgt tactgacgtt atgccgctga ccgaagtgct
     2821 ggaatggcgg tataaagcga ttcagagaag cggggccaac gatgagtgat aacaacctgc
     2881 gtctgcaggt cattcttaat gcggttgaca agctcacccg cccatttcga tctgcgcagg
     2941 ccagttcaag agaactggct gctgctgtca aaaaatcccg cgatgcaata aagcagcttg
     3001 atcaggccgg gagcagtctg gacagcttcc gaaagctgca ggcagaaaat cagaaattag
     3061 gcgacaggct gaactatgcc cgccagcgtg caaatttgct cagtcaggaa ctgggagcga
     3121 tggggccgcc ttcgcaacgt caggttgttg ctctgggccg tcaacggctg gctgttcagc
     3181 gcctggaaga acgccagaaa aagctgcagc agcagacggc gcttgtgcgt gctgaactgt
     3241 accgggcggg aatttctgcg aaagatgatg cgggagcaac tgcccgttta gcccgtgaaa
     3301 catcacgtta taaccaggaa ctgtcgaaac aggaggcgcg gctgaagcga ctgggggaag
     3361 ctcagcgcag gatgaatgtg gcgcgtgcca gttatgcccg ttcgctggag gtgcgcgatc
     3421 gcatcgcagg agccggagcc accaccacgg cggcagggct ggcaatgggg acgccagtga
     3481 tggcggcagt aaaaagctat accagcatgg aagatgccat gaaaggtgtg gcaaagcagg
     3541 tcaatggtct gcgtgacgat aatggcaacc gcactgcacg tttttatgaa atgcaggatg
     3601 ccatcaaggc tgccagcgaa cagttgccga tggaaaacgg tgcggtagac ttcgctgcac
     3661 tggttgaagg tggtgcgcgc atgaacgtcg caaaccctga cgacagctgg gaagaccaga
     3721 aacgtgacct gctggccttc gccagtacgg cagcaaaggc ggcaacagcc tttgagctgc
     3781 cagcggatga actgtcagaa agtctgggga aaatcgccca gctctacaaa atccctaccc
     3841 gcaatattga acagctcggt gatgcgctga actatctgga tgataacgcc atgtcgaaag
     3901 gggcagacat tattgatgtc atgcaacgtc tgggcggtgt ggctgaccgt ctggattatc
     3961 gtaaagcggc ggcgctgggt tccacctttc tgacactggg cgctgcgccg gaggttgcag
     4021 ccagtgcagc aaacgcgata gtgcgtgaat tgtccattgc caccatgcaa agcaagagtt
     4081 tctttgaagg gatgaatctg ctgaaactca atcctgaagt tattgaaaag cagatgacga
     4141 aggatgcgat gggaactatc cagcgtgtgc tggagaaggt gaacgcactg ccgcaggaca
     4201 agcgtctgtc tgccatgacc atgttgtttg gtaaagagtt tggcgatgac gcggcgaaac
     4261 tggcaaacaa cctgccggaa ctgcagcgcc agctaaaact gacagcgggc aatgatgcgc
     4321 tcggctccat gcagaaagaa tccgacatta acaaggactc actttctgcg cagtggttgc
     4381 tggtcaaaac cggagcgcag aacaccttca gcagcctggg cgaaacgctg cgccagccgc
     4441 tgatggatat tctgtacatg gtgaaaagcg tcacgggagc atcgcgtcgt tgggtggaag
     4501 ctaacccgga actgacgggc acactgatga aagtagccgc tgtggtggct gccgttaccg
     4561 tgggcctcgg caccttagcg gtggcgctgg ctgcagtgct ggggccgctg gcagtcatcc
     4621 gtctggggtt ctctgtgctg ggtatcaaaa cgttaccttc cgttacggca gcagtaaccc
     4681 gaactagcag cgcgttgtcc tggctggctg gcgcaccact ggcactgctg cgacgcgggc
     4741 ttgcttcatc gggcaacgct gcgggtttac ttactgcgcc gttgtcgtct ttgcgccgca
     4801 cggcatcact gacggggaat gtcctgaaaa ctgtagcagg tgcgccggtt gcacttttgc
     4861 ggtctggatt atccggttta cgtgctgttg ctgtgatgtt tatgaatcca ctggcagcac
     4921 tacgcggtgg gctggctgcc gcaggcgcgg tgctgcgtgt gctcgcatcc ggcccgctgg
     4981 cgatgttgcg cattgccctg tatgccgtat ctggtctgtt aggtgctctg ctcagtccga
     5041 taggtcttgt ggttactgca ctggcgggcg tggcgctggt tgtctggaaa tactggcaac
     5101 ccatcaccgc atttctcggt ggcgtggtgg aaggattcaa agcggcggca ggtcccatca
     5161 gtgcagcatt cgaaccactt aagcctgtgt ttcagtggat tggcgacaaa gtgcaggcgt
     5221 tgtggggctg gtttactgat ctgctgacgc ccgttaagtc gacctctgcc gaactgcaga
     5281 gcgcagcggc aatggggcga cgattcgggg aggcactggc ggaagggctg aatatggtca
     5341 tgcatccgct ggactccctg aaatccggcg tttcctggtt gctggagaaa ctcggtattg
     5401 tcagtaaaga ggctgcaaag gcgaaactgc cggaaagcgt gacgcgtcag caacctgcga
     5461 cggtgaatgc agacggtaaa gtgatgatgc catcaggtgg tttcccatca tggggatatg
     5521 gttttgcggg gatgtatgac agcggtgggt atatcccgcg cgggcagttt ggcattgtcg
     5581 gtgaaaacgg gcctgaaatt gtcaacggcc cggcaaacgt gaccagccgg agaaatacag
     5641 ctgcactggc tgccgttgtt gccggaatga tgggtgttgc tgccgcgcca gcagagcttc
     5701 caccgttgca ccctttggca tttcccgcga aaggcggtga agcgatggtg agtcgcgcag
     5761 ccactgtgtc gcccgttcaa cggattgagg caccgacgca gatcatcatt cagacgcagc
     5821 caggacaaag tgtgcaggat attgcgcggg aggtggcccg ccagcttgat gaacgtgaac
     5881 gcaggctgaa ggcaaaagcc aggagtaact acagcgatca ggggggatac gacgcatgat
     5941 gatggtgctg ggattgtacg tgtttatgct gcgcactgtg ccgtatcagg aactgctgta
     6001 tcaacgcagc tggcgacatg cggcaaacag ccgggtcaac cgacgtccat ccacgcagtt
     6061 tctgggaccg gacaacgaca tgctgacgct ttctggtgtt cttatgccgg agataacggg
     6121 cggcagactg tcgttgctgg ctctggagca gatggcagaa cagggaaaag catggcccct
     6181 gattgaaggc agcggcacga tttacggcat gtatgtgatt gagggactga atcagactaa
     6241 aacggagttt ttccgcgatg gtatgccgcg ccggattgag ttcaccctgt cgctcaaacg
     6301 ggtggatgaa tccctgtccg atatgttcgg tgatctcagt gcgcagctga ataatttgca
     6361 ggatacggta acgtctgcct taagcgatat cagtaaaacg gtgggagggc tgctgtcgtg
     6421 aatttcagct ctgaactgct taacaaaggc aacaaaactc ccgcattcag catcagtatt
     6481 gaggggaagg atatcaccac tgtgctggat aaccgcctga tgagtctgac gctgacggac
     6541 aatcggggct ttgaagcaga ccagcttgat ttggagctgg acgacgccga cggaaaaatc
     6601 gtgctgccgc gccgtggggc tgtcattacg ctggcgttgg gctggaaggg gcagccgctt
     6661 ttcccgaaag gagcattcac ggtggacgag attgaacaca ctggcgcacc ggaccgcctg
     6721 actatccggg cgcgaagtgc tgattttcgt gaaaccctga atacccgccg tgaaaaatcg
     6781 tggcacaaga ccaccgttgg ggaagtggtg aaggaaatag ctgcgcggca caaactgaag
     6841 atggcattgg gtgaagacct gtcggataaa cccgtggagc atatagacca gaccaatgag
     6901 agtgacggca gttttctgat gcggctggcg cgccagtacg gtgctattgc gtcggtgaaa
     6961 aatggcaatc tgttattcat ccggcaggga cagggtaaaa gcgccagcgg taaaccactg
     7021 ccggtgatca ctatcacacg gaaggacggc gacagtcacc gctttaccct ggcagatcgc
     7081 ggagcctaca cgggcgtaat tgccagctgg ttgcataccc gcgaacccgc gaagaaagaa
     7141 agcaccacgg tgaagcgtaa gcgcaggact aagaagcaga agaaagagcc ggaagcgaag
     7201 cagggcgatt acctggtggg gacggatgaa aacgtgctgg tacttaatcg cacttatgcc
     7261 aaccggagca acgccgaacg agcggcgaaa atgcagtggg aacgcttgca acgcggcgtt
     7321 gcgtcattct cgctacaact ggcggaaggt cgggcagatc tctacacgga aatgcctgtg
     7381 aaggtcagtg gctttaaaca gccgatagat gatgcggaat ggaccattac caccctgaca
     7441 catactgtca gcccggataa tggttttacg accagtctgg agcttgaagt gaggattgat
     7501 gatttcgaaa tggaatgatt cttcgcaatg gagaactttt aagtttgcaa aatggaataa
     7561 tgcggtatca ttattgtgaa tttagcaaaa atggggagag ctcgaaaaat gatgatttgc
     7621 ccactgtgtg gaagtgccgc ccatactcgc agcagttttc aggtatcttc attgaccaaa
     7681 gagcgttaca accagtgcca gaacattaac tgcagccata cttttgttac ccatgaaact
     7741 tttgttcgtt cgattgcaac gccaaaagag tcaaatccgg ttcagccgca tccaatgaaa
     7801 tcaggacagg tggcgctctc tctttgacgc tgccgccatt ttgtcgccat cgttaaaaaa
     7861 cagtgtttct aacatcatga ttttaaacag cttaaatttc aggcaacaaa aaacccatta
     7921 accttgctcc agccgatcta ccgaaagagg gcggaaggta tgacctgcct attgctgttg
     7981 cgcttctggc cgcgtctgag cagcttacag cgtcgaatct tgaggcatat gagctggtgg
     8041 gtgagttagc gcttacaggc gcattacgcg gcgttcctgg cgcaatatca agtgcaacgg
     8101 aagccatcag ggccggcaga aatattatcg tcgcaacaga gaacacggcg gaggttgggc
     8161 ttatcagcaa agaaggatgt tttatcgccg atcatctaca aaccgtctgc gcctttctgg
     8221 aagggaaaca cgccctggaa agacctttag ctcaggatat ggcatcgtct accgcaactg
     8281 ccgatcttcg cgatgtgatc ggtcaggagc agggtaaacg cggcctggag attacagcgg
     8341 cagggggaca taatctgcta ttgatcggcc cgccgggtac gggtaaaacc atgctggcca
     8401 gtcgactgag cgggattctt ccaccattaa gcaatgaaga ggcgttggaa agcgccgcga
     8461 tcctcagtct ggttaatgcc gatacggtac aaaaacgatg gcagcaacgt ccctttcgct
     8521 cacctcatca tagcacctca cttactgcta tggtcggcgg cggcgcaata cccgccccgg
     8581 gagagatatc gctggcgcac aacggaattt tgttccttga tgaattgcct gaatttgaac
     8641 gacgcacact ggatgcgcta cgtgaaccta tagaatccgg tcaaattcat ttatcccgta
     8701 ccagagcgaa aataacgtac cctgccaggt tccagttaat cgccgcaatg aatcccagcc
     8761 cgaccggaca ttatcaggga aaccataatc gctgcacgcc agaacagaca ctacgttacc
     8821 ttaatcggtt gtcaggcccg tttcttgatc gttttgacct ttcgcttgag ataccgcttc
     8881 ctccgcccgg gattcttagc caacacgcct caaagggtga gagcagcgct acggtaaaaa
     8941 agcgggtcat cgccgcccat aaacggcagt accgacgcca gaagaagtta aacgcgcgtc
     9001 tggagggtcg cgaaatccaa aaatattgtg ttttacatca cgatgacgcc cgctggcttg
     9061 aagacacgct ggtgcatctt ggattatcca ttcgcgcctg gcagcgttta ctaaaagttg
     9121 ccagaaccat tgccgacata gaactggctg accagatctc gcgtcagcat ttgcaggagg
     9181 cggtaagcta tcgggcgata gacaggttgt taattcattt gcaaaagctg ttggcgtaaa
     9241 aaaagggcat tacgcc
//
LOCUS       DAJVBX010000185         9200 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.185, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000185 DAJVBX010000000
VERSION     DAJVBX010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 9200)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9200)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9200
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.185"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            61..2505
                     /gene="dmsA"
                     /locus_tag="OPV72_003687"
     CDS             61..2505
                     /gene="dmsA"
                     /locus_tag="OPV72_003687"
                     /EC_number="1.8.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethylsulfoxide reductase subunit A"
                     /protein_id="HCR9915876.1"
                     /translation="MKTKIPDAVLAAEVSRRGLVKTTAIGGLAMASSAFTLPFTRIAN
                     AAEAISPTKTDEKVVWSACTVNCGSRCPLRMHVVDGEIKYVETDNTGNDDYDGLHQVR
                     ACLRGRSMRRRVYNPDRLKYPMKRVGARGEGKFERISWDEAYDIIATNMQRLIKEYGN
                     ESIYLNYGTGTLGGTLTRSWPPGKTLVARLMNCCGGYLNHYGDYSSAQIAAGLNYTYG
                     GWADGNSPSDIENSKLVVLFGNNPGETRMSGGGGTYYLEQARQKSNARMIIIDPRYTD
                     TGAGREDEWIPIRPGTDAALVNGLAYVLITENMVDQPFLDKYCVGYDEKTLPASAPKN
                     GHYKAYILGLGKDGIAKTPEWAAQITGIPADRIIKLAREIGSAKPAYICQGWGPQRHA
                     NGEIATRAISMLAILTGNVGINGGNSGAREGSYALPFERMPTLENPVETSISMFMWTD
                     AIERGPEMTALRDGVRGKDKLDVPIKMIWNYAGNCLINQHSEINRTHEILQDDSKCEM
                     IVVIDCHMTSSAKYADILLPDCTASEQMDFALDASCGNMSYVIFTDQAIKPRFECKTI
                     YEMTSELAKRLGVEQQFTEGRTQEEWMRHLYEQSRKSIPNLPTFEEFRKQGIFKQRDP
                     EGHHVAYKDFREDPQANPLTTPSGKIEIYSQALADIAATWELPEGDVIDPLPIYTLGF
                     ENYNDPLTDKFPLQLTGFHYKARVHSTYGNVDVLKAACRQEMWINPMDAQKRGINNGD
                     KVRIFNDRGEVHIEAKVTPRMMPGVVALGEGAWYDPDAKRVDQGGCINVLTSQRPSPL
                     AKGNPSHTNLVQVEKA"
     gene            2516..3133
                     /gene="dmsB"
                     /locus_tag="OPV72_003688"
     CDS             2516..3133
                     /gene="dmsB"
                     /locus_tag="OPV72_003688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000213046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethylsulfoxide reductase subunit B"
                     /protein_id="HCR9915877.1"
                     /translation="MTTQYGFFIDSSRCTGCKTCELACKDYKDLTPDVSFRRIYEYAG
                     GDWQEDNGVWHQNVFAYYLSISCNHCEDPACTKVCPSGAMHKRDDGFVVVNEEVCIGC
                     RYCHMACPYGAPQYNAAKGHMTKCDGCYDRVAEGKKPICVESCPLRALDFGPIDELRK
                     KHGELAAVAPLPRAHFTKPNIVIKPNANSRPTGDTTGYLANPKEV"
     gene            3135..3998
                     /locus_tag="OPV72_003689"
     CDS             3135..3998
                     /locus_tag="OPV72_003689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase anchor subunit"
                     /protein_id="HCR9915878.1"
                     /translation="MGSGWHEWPLMIFTVFGQCVAGGFIVLALALMKGDLRAETQQRV
                     IACMFGLWVLMGIGFIASMLHLGSPMRAFNSLNRVGASALSNEIASGSVFFAVGGIGW
                     LLAVLKKLPPALRTLWLIITMVLGVVFVWMMVRVYNSIDTVPTWYSVWTPLGFFLTLF
                     MGGPLLGYLLLRIAGVNGWAMRLLPAVSVLALVVIAIMVAMQGAELATIHSSIQQASA
                     LVPDYGSLMAWRMVLLAAALCCWIVPQLKGYQPAVPLLSVAFILMLAGELIGRGVFYG
                     LHMTVGMAVAS"
     gene            4348..5496
                     /locus_tag="OPV72_003690"
     CDS             4348..5496
                     /locus_tag="OPV72_003690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR9915879.1"
                     /translation="MSIYTRPVMLLLCGLLLLTLAIAVLNTLVPLWLAQANLPTWQVG
                     MVSSSYFTGNLVGTLFTGYLIKRIGFNRSYYLASLIFAAGCVGLGVMVGFWSWMSWRF
                     IAGIGCAMIWVVVESALMCSGTSHNRGRLLAAYMMVYYMGTFLGQLLVSKVSGELLHV
                     LPWVTGMILAGILPLLFTRIVNQQTQARHSSSISAMLKLRQARLGVNGCIISGIVLGS
                     LYGLMPLYLKHQGMANASIGFWMAVLVSAGILGQWPMGRLADKFGRLLVLRVQVFVVI
                     LGSIAMLTQAAMAPALFILGAAGFTLYPVAMAWACEKVEHHQLVAMNQALLLSYTVGS
                     LLGPSFAAMLMQNYSDNLLFIMIASVSFIYLLMLLRNVGQTPNPVAHI"
     gene            5714..7135
                     /locus_tag="OPV72_003691"
     CDS             5714..7135
                     /locus_tag="OPV72_003691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCR9915880.1"
                     /translation="MPNVQEKQLRWYNIALMSFITVWGFGNVVNNYANQGLVVVFSWV
                     FIFALYFIPYALIVGQLGSTFKEGKGGVSTWIKHTMGPGLAYLAAWTYWVVHIPYLAQ
                     KPQAILIALGWALKGDGSLIKEYTVVALQGLTLALFVFFMWVASRGMKSLKVVGSVAG
                     IAMFIMSILYVVMAVTAPAITNVEIATANITWQSFIPHIDFTYITTISMLVFAVGGAE
                     KISPYVNQTRNPGKEFPKGMLFLAVMVAVCAILGSLAMGMMFDSRHIPDDLMTNGQYY
                     AFQKLGEYYHMGNSLMVIYAIANTLGQIAALVFSIDAPLKVLLGDADSKYIPQRLCRT
                     NASGTPVNGYLLTLVLVAILIMLPTLGIGDMNNLYKWLLNLNSVVMPLRYLWVFVAFI
                     AVIRLAQKYKPEYVFIRNRALALTVGIWCFAFTAFACLTGIFPKMEAFTPEWAFQLTL
                     NIVTPFVLVGLGLIFPLLARRNT"
     gene            complement(7427..8203)
                     /gene="pflA"
                     /locus_tag="OPV72_003692"
     CDS             complement(7427..8203)
                     /gene="pflA"
                     /locus_tag="OPV72_003692"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase 1-activating protein"
                     /protein_id="HCR9915881.1"
                     /translation="MTNESVAVTADKKPVIGRIHSFESCGTVDGPGIRFITFFQGCLM
                     RCLYCHNRDTWDTHGGKEITVEDLMKEVVTYRHFMNASGGGVTASGGEAILQAEFVRD
                     WFRACKKEGIHTCLDTNGFVRRYDPVIDELLDVTDLVMLDLKQMNDEIHQNLVGVSNH
                     RTLEFAQYLSKKNVKVWIRYVVVPGWSDDDDSAHRLGEFTRDMGNVEKIELLPYHELG
                     KHKWVAMGEEYKLDGVKPPKKETMERVKGILEQYGHKVMY"
     gene            8797..9200
                     /locus_tag="OPV72_003693"
                     /pseudo
     CDS             8797..9200
                     /locus_tag="OPV72_003693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459947.1"
                     /note="involved in bacterial survival in the host cell;
                     involved in macrophage replication and filament formation;
                     frameshifted; incomplete; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pathogenicity island 1 protein SopD2"
BASE COUNT         2151 a         2170 c         2457 g         2422 t
ORIGIN      
        1 atataaaatt ctatacatcg ttttattgct tttttattgt gagcagcaga gtgagccctt
       61 atgaaaacta agatccctga tgccgtgctg gcagccgagg tgagccgtcg tggtttagtc
      121 aaaaccaccg cgataggcgg cctggcgatg gccagtagcg catttaccct gccatttacc
      181 cgcatcgcta acgccgcaga ggcgataagc ccgacgaaaa ccgacgagaa agtcgtctgg
      241 agcgcctgta cggtaaactg tggcagccgt tgtccgctac gtatgcatgt tgtggatggc
      301 gaaatcaaat atgtagaaac ggataatacc ggaaacgatg attacgatgg cctgcaccag
      361 gttcgcgcct gcctgcgcgg tcgttctatg cgtcgtcgcg tctataaccc ggatcgtctc
      421 aagtatccga tgaagcgcgt cggcgcgcgc ggcgaaggta aatttgagcg tattagctgg
      481 gacgaagcct acgatatcat tgccaccaat atgcagcgtc ttatcaaaga gtatggcaac
      541 gagtccattt atctgaacta tggcacggga acgctgggcg gcactttgac acgttcatgg
      601 ccgccgggaa aaacgctggt cgctcgtctg atgaactgct gcggcggtta tcttaatcac
      661 tacggtgatt actcttccgc gcaaatcgca gcgggtctga attacaccta tggcggctgg
      721 gcggatggca atagtccatc cgacattgaa aacagtaagc tggtggtgtt gtttggtaat
      781 aaccctggcg aaacccgcat gagcgggggc ggtggaacgt attatcttga acaggcgcgg
      841 cagaaatcaa acgcgcggat gatcattatc gatcctcgtt acaccgacac cggcgccggt
      901 cgcgaagatg agtggattcc gattcgtcca ggtaccgatg cggcgctggt caatggtctg
      961 gcatatgtct taatcaccga gaacatggtc gatcagccgt tcctggataa atattgcgtc
     1021 ggttatgacg aaaaaacctt gcctgccagc gcgccgaaaa acggtcacta caaagcctat
     1081 attctgggct tgggtaaaga cggtatcgca aagacgccgg agtgggcggc gcaaattacc
     1141 ggtattccgg cagatcgcat tattaaactg gcgcgagaaa tcggcagcgc taaacccgcc
     1201 tatatttgcc aggggtgggg gccacaacgt catgctaatg gagaaatcgc cacgcgcgcc
     1261 atctcgatgc tggcgatcct gacgggtaat gttgggatta acggcggtaa cagcggcgcg
     1321 cgcgaagggt cttatgccct gccatttgaa cgtatgccca cgttggaaaa tccggttgaa
     1381 accagcatct ccatgtttat gtggaccgat gccattgaac gcggcccgga aatgacagcg
     1441 ctgcgtgatg gcgtgcgggg gaaagataag ctggacgtgc cgatcaaaat gatctggaac
     1501 tatgctggca actgtttgat taaccagcac tctgagatta accgcaccca cgaaatcctg
     1561 caggatgaca gtaaatgtga aatgatcgtc gttatcgact gtcatatgac ctcgtcggca
     1621 aaatacgccg atattctgtt gcctgattgc actgcttctg agcagatgga ctttgcgctg
     1681 gatgcctcct gcgggaacat gtcttacgtt atcttcactg accaggcgat taaaccgcgc
     1741 ttcgagtgta agacgattta tgagatgacc agcgaactgg cgaaacgtct tggcgtggaa
     1801 caacagttta ccgaaggccg gacgcaagaa gagtggatgc gtcatctgta cgaacagtcg
     1861 cgtaaatcca ttccgaatct gcccaccttt gaggagttcc gtaagcaagg catcttcaaa
     1921 cagcgcgacc ccgaaggcca ccatgtcgcc tataaagact tccgcgaaga tccgcaagcg
     1981 aatccactta caacgccatc gggcaagatt gaaatctatt cacaggcgtt ggcggatatc
     2041 gccgccacct gggagctgcc ggaaggcgac gtgatcgatc cattaccgat ctacacgcta
     2101 ggttttgaaa actataacga tccgctaacg gataaattcc cgctgcagtt gacgggtttc
     2161 cactataaag cgcgtgtgca ttccacttat ggcaacgtag acgtactgaa agccgcctgt
     2221 cgccaggaaa tgtggattaa cccaatggat gcgcagaaac gcggtatcaa caatggcgat
     2281 aaagtccgca tcttcaacga tcgcggcgaa gttcatatcg aggctaaagt gacgccgcgc
     2341 atgatgccgg gcgtggtcgc tctgggagaa ggcgcatggt atgacccgga tgcaaaacgc
     2401 gtggatcagg gcggatgtat taacgtactg accagtcaac gtccttctcc gctggcgaag
     2461 gggaacccgt cacatacgaa cctcgttcag gttgaaaagg cgtaaggagt aaccgatgac
     2521 aacccagtat ggatttttta ttgattccag ccgttgcacc ggttgcaaaa cctgcgaact
     2581 ggcctgcaag gactacaaag atttgacccc ggatgtcagc ttccgccgca tttatgagta
     2641 tgcaggtggc gactggcagg aggataacgg cgtctggcac cagaacgtct ttgcctacta
     2701 tctctccatc tcctgtaacc actgcgaaga cccggcctgc accaaagtct gcccgagcgg
     2761 cgcgatgcac aagcgcgatg acggttttgt ggtggtgaac gaagaggtct gtatcggttg
     2821 ccgctactgc cacatggcct gcccgtacgg cgcgccgcag tacaacgcgg ccaaaggtca
     2881 tatgaccaag tgcgatggct gttatgaccg ggtggcggaa ggtaagaaac cgatctgcgt
     2941 cgaatcctgt ccgctgcggg cgctggattt cggcccgata gacgaactgc gcaaaaaaca
     3001 cggtgagctg gctgccgtcg cgccgttgcc gcgcgcgcat ttcacgaagc cgaatattgt
     3061 gattaaaccc aacgccaaca gccgcccgac cggggacacc accggttatc tggccaatcc
     3121 gaaggaggta taagatggga agtggatggc atgaatggcc gttgatgatc ttcacggtct
     3181 ttggtcagtg cgtggccggt ggttttattg ttctggctct ggcgctgatg aagggcgacc
     3241 tgcgcgcgga aacgcagcag cgggtgatcg cctgtatgtt tggtctgtgg gtgctgatgg
     3301 ggattggctt tatcgcctcg atgctgcatc tgggctcgcc gatgcgcgcg tttaactcgc
     3361 ttaaccgcgt gggtgcttcc gcactgagca atgaaattgc cagcggctcg gtgttttttg
     3421 cggtcggcgg gatcggctgg ctgctggcgg tactgaaaaa gctgccgccg gcactgcgca
     3481 cactctggct gattatcacg atggtactgg gcgtcgtctt cgtctggatg atggtacgcg
     3541 tctataacag catcgataca gtaccgacct ggtatagcgt ctggacgccg ctgggcttct
     3601 tcctgacgct ctttatgggt ggcccgctac tgggttatct gctgctgcgc atcgcgggcg
     3661 tgaacggttg ggcgatgcgt ctgttgcctg cggtttcggt gctggcgctg gtggttattg
     3721 ccattatggt ggccatgcag ggcgcggaac tggcgacgat tcacagttcc attcagcagg
     3781 cgtctgctct ggtgccggat tatggttcgc tgatggcctg gcgtatggtg ctgcttgcgg
     3841 cggcgttgtg ctgctggatt gtgccacagt taaaagggta tcaacctgcg gtaccgttac
     3901 tctctgtcgc cttcattctg atgctggcgg gggaattgat tggccgcggc gtattctatg
     3961 ggctgcatat gaccgtgggc atggcggtag ccagctaacg cgttgacgcg cattcggcct
     4021 gcagaacgtg caggccgaat acgcctttag ccgccgtcaa tctaaggaat ataaccgggg
     4081 cggagaaggc gcatataaat ccatagagaa gaaaacgaag ctaaaggaac catgaaattt
     4141 ttcgactgaa caaaacgccg attttgcggg ttagatcaat aaaaacaagg ggatgaattt
     4201 ttagcctttc aatatattca cgtgcagaat aagtaaatcg aatcgatagt ctcaaaactt
     4261 gcggatcgcc catgcggagc cgattgacaa tgtttttggc gatggcatga tgcgcatgaa
     4321 atttgaactt cctcacggtt tttattcatg tccatctata cccgtcccgt catgcttttg
     4381 ctgtgcgggc tacttttgtt gaccctggcc attgcggtac tgaatacgct tgtgccgctg
     4441 tggcttgctc aggcaaacct tccgacctgg caggtgggga tggtcagctc gtcttatttt
     4501 accggcaatc tggtcgggac gttatttacc gggtatttaa ttaaacgcat tgggtttaac
     4561 cgtagctatt atcttgcctc gctgatcttc gccgcgggtt gtgtcgggtt gggggtgatg
     4621 gtggggttct ggagctggat gagctggcgt tttattgccg gtatcggctg cgccatgatt
     4681 tgggtggttg tcgaaagcgc gttgatgtgc agcggaacct cgcataatcg cggacgcctg
     4741 ctggctgcct atatgatggt ctattacatg gggaccttcc ttggacaatt attggtcagt
     4801 aaagtatctg gtgaattgct gcacgtcctt ccctgggtga ccggaatgat tctggcggga
     4861 attctgccgc tactctttac ccgaattgta aatcagcaaa cgcaggcacg tcattcctct
     4921 tctattagcg ccatgctgaa gctacgccag gcgcgtcttg gcgtgaatgg ttgtattatt
     4981 tccggcattg ttcttggttc attatatggc ctgatgccgt tatatctgaa gcatcagggg
     5041 atggctaacg ccagcatcgg tttctggatg gcggtgctgg tgagcgccgg tattttgggg
     5101 caatggccaa tgggacgtct ggcggacaaa tttggtcgct tgctggtatt acgcgtacag
     5161 gtattcgttg tcatactcgg cagtattgcc atgttaaccc aggcggcgat ggcgccagct
     5221 ctgtttattc tgggggcggc gggttttacg ctttatcccg ttgcaatggc ctgggcctgt
     5281 gaaaaagtcg aacaccacca gcttgtggca atgaaccagg cgctgttgtt aagttatacg
     5341 gtagggagcc tgttggggcc gtcttttgct gcgatgttaa tgcagaatta ttcagataat
     5401 ctgctgttta ttatgatcgc cagcgtatcg tttatttatc tgctgatgct gttacgtaac
     5461 gtcggccaga cgcctaatcc tgtcgcccac atctaactgt tctctgaatc gtatgcagga
     5521 cgtgagtctt gcatactctt tgtttatgtt ttacgtaaaa taattgacct gcataatttt
     5581 cttgctttac tgaaaaataa aatgtgccga aggttataat tttgcgctcc tctattttct
     5641 ctcttcgtct ttaccgcgca taatcccccg cttcatttat agtaatagca ttgtgttcac
     5701 gaaggatcgc gttatgccga atgtgcagga aaaacagttg cgatggtaca acatcgccct
     5761 gatgtcgttt attaccgttt ggggattcgg caatgttgtc aataactatg ctaaccaggg
     5821 gttagtggtt gtcttctcct gggtgtttat ttttgcgctc tattttattc cttatgcctt
     5881 aatcgtgggg caactgggct caaccttcaa agagggaaaa gggggcgtca gtacctggat
     5941 taagcatacg atggggccgg ggttggctta ccttgcggca tggacttatt gggtcgtgca
     6001 tattccctac ctggcgcaaa agccgcaggc gatactcatt gcattgggat gggctttaaa
     6061 aggcgacggc tcgttgataa aagaatatac cgtcgttgcc ttgcaggggc tgacgctggc
     6121 attgtttgtt ttctttatgt gggttgcttc ccgggggatg aaatcgctaa aggttgttgg
     6181 gtctgtggct gggattgcca tgtttatcat gtcaatttta tatgttgtga tggcagtgac
     6241 cgcgccagca attacaaacg ttgaaattgc gaccgctaac atcacctggc agtcatttat
     6301 tcctcatatc gattttacct atatcaccac catctctatg ttggtctttg cggttggtgg
     6361 ggcagagaag atctcgcctt atgtcaacca gacgcggaat ccaggaaaag aatttccgaa
     6421 ggggatgctc tttttagccg tcatggttgc ggtctgcgct atcctcggtt cgttggcgat
     6481 gggaatgatg tttgattccc ggcatatacc tgacgattta atgaccaatg ggcaatatta
     6541 tgcattccag aaattgggtg agtattacca tatgggtaat tcattaatgg tgatttatgc
     6601 cattgccaat actctggggc aaatcgccgc gctggtgttt tctattgatg cgccactgaa
     6661 agtcttactg ggtgatgcag acagtaaata tatcccgcag cgcttatgtc gtactaacgc
     6721 ttcaggtaca ccagttaacg gttatttgct gacattagtg ttggtcgcta tcttgattat
     6781 gttgccaacg cttggcatcg gcgatatgaa caacctgtac aaatggctgc ttaatctcaa
     6841 ttcagtcgtt atgccgctgc gctatctgtg ggtatttgtc gcctttattg ccgtcattcg
     6901 actggcgcaa aagtacaaac ccgaatatgt gtttattcgc aaccgggcgt tggcgttaac
     6961 tgtgggaata tggtgttttg ccttcaccgc gtttgcctgc cttaccggta ttttccccaa
     7021 aatggaggcg ttcacgccgg agtgggcatt ccagctgacg ttgaacatcg tgacaccttt
     7081 tgtcctggtc gggttgggat taattttccc actgctggcg cgtagaaaca cataacgacg
     7141 ctcttttcca cggcgctcct gtcaggcgag cgccttttaa ggttacaggt gcctgggttc
     7201 caggcggaga ccacggtatt aacaggcgcc ggggcagcaa tagttgtcag accttcaacc
     7261 cagcagcaga taagcgactc tgtatttaat acctggtaag cgcaatattg ttaaccaggc
     7321 ctgtctgacg gcggggtcgg gtattttagc ggtaagagcg ttacccagac agcaaaacgg
     7381 ctaccgtcat gggtagccgt ttaaaagcgg ataagatagc aggcgattaa tacatcactt
     7441 tatgaccata ctgctcaaga atacccttta cacgttccat ggtctctttt ttaggcggct
     7501 tcacgccatc cagtttatat tcttcgccca ttgccaccca tttatgtttg cccagctcat
     7561 gatagggcag cagttcgatt ttttcgacat tacccatatc gcgggtaaac tcacccaggc
     7621 gatgcgcgga atcatcgtcg tcagaccagc cgggaacgac aacgtaacgg atccagacct
     7681 tcacattttt ctttgataaa tactgcgcga attccagcgt ccggtgattg gatacaccga
     7741 ccagattctg gtggatctca tcattcatct gcttgagatc gagcatcacc agatcggtaa
     7801 cgtccaacag ttcatcaatc accgggtcat aacggcgcac aaagccgttg gtgtcgagac
     7861 aggtgtggat accttctttt ttacaggcgc gaaaccagtc gcgtacaaat tctgcctgca
     7921 aaatggcctc gccgccggat gccgtcacgc cgccgccaga agcattcata aaatgccgat
     7981 aggtcaccac ctctttcatt aagtcttcaa cggtgatttc tttaccgcca tgcgtatccc
     8041 atgtgtcgcg gttatggcaa tacaggcagc gcatcaggca gccctggaaa aaggtaataa
     8101 agcggatgcc tgggccatca acggtgccac aggactcaaa ggagtgaatg cgaccaataa
     8161 ccggcttttt atcagcagtt actgcaacac tttcatttgt aatacaatcg gttaagttac
     8221 tcatatcgct tcggctagct ctaaataaca tggggtttat ggacacattc cgggcatgtt
     8281 gagcacccta gtaagggggt tgcatcctgt aaaaaagcgg tactgcgagc gtaaattttg
     8341 gactacagaa tgtgtggctg ttccagaatg tgctgcaatg gagctatttt acctctattc
     8401 agtataaaat atacggcaaa tctatgctgc atagcttgca ccgccagaaa ttgtggctca
     8461 ttcatcagct cgtaacgccc gaaccgcaat acatactgta agtgtatcat ccatagcgtc
     8521 ctggttttgc tgtttatgaa ccgcctcttt tttcaaatgg ttgatgccgt ttttgtggtc
     8581 agaacaaaaa taattctcaa cataattcag atgtgtccaa agaacgttac gcctgtccag
     8641 tgcctggcgt tgcattcaac gcgcaatcag gtgtaaatct gatgtcattt ctaaacccgg
     8701 actgattcaa tctcttaaat agagtgtggt tttaatcaaa aaatgagagc aacggattgg
     8761 attttgcttt cgcggtaaat aatcaaagga gttattatgc cagttacgtt aagttttggt
     8821 aatcgtcata actatgaagt taatacttca cggctaaccc gtttgatgag tcctaataaa
     8881 gaagaagcgc tatacatggg ggtatgggat agatttaagg actgcttcag aacacacaaa
     8941 aaaaagaggt gctggaggta ttatatacac tcatccatgg atgtgaacgt gaaaatcaag
     9001 ctgaacttaa tgttgatata accggcatgg agaagataca tgcctttaca caattaaaac
     9061 aatatgctaa tccatctcaa caagagcgct ttgttatgcg ttttgatatg aatcagacaa
     9121 aagttttatt tgagattgat ggccaggtta ttgataaatg taatttgcat cgtctcctca
     9181 acgtttcaga aaactgtatt
//
LOCUS       DAJVBX010000186         9180 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.186, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000186 DAJVBX010000000
VERSION     DAJVBX010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 9180)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9180)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9180
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.186"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            414..1313
                     /gene="yegS"
                     /locus_tag="OPV72_003694"
     CDS             414..1313
                     /gene="yegS"
                     /locus_tag="OPV72_003694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid kinase YegS"
                     /protein_id="HCR9915882.1"
                     /translation="MANFPASLLILNGKSADNQPLREAITLLRDEGIQIHVRVTWEKG
                     DAQRYVDEARRLGVETVIAGGGDGTINEVSTALIQIRDGVAPALGLLPLGTANDFATS
                     AGIPEALDKALKLAIAGNAMEIDMARVNDKTCFINMATGGFGTRITTETPEKLKAALG
                     GVSYLIHGLMRMDTLTPDRCEIRGENFHWQGDALVIGIGNGRQAGGGQQLCPTALIND
                     GLLQLRIFTGEELLPALFSTLTQSDDNPNIIDGASAWFDIHAPHEITFNLDGEPLSGQ
                     EFHIEVLPGALRCRLPPDCPLLR"
     gene            complement(1366..2418)
                     /gene="fbaB"
                     /locus_tag="OPV72_003695"
     CDS             complement(1366..2418)
                     /gene="fbaB"
                     /locus_tag="OPV72_003695"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006820796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I fructose-bisphosphate aldolase"
                     /protein_id="HCR9915883.1"
                     /translation="MTDIAQLLGKDADSLLQHRCMTIPSDQLYLPGKDYVDRVMIDNN
                     RPPAVLRNMQTLYNTGRLAGTGYLSILPVDQGVEHSAGASFAANPRYFDPKNIVELAI
                     EAGCNCVASTYGVLASVSRRYAHRIPFLVKLNHNETLSYPTEYDQTLYASVEQAFNMG
                     AVAVGATIYFGSEQSRRQIEEISAAFERAHELGMVTVLWAYLRNSSFKKDGVDYHVSA
                     DLTGQANHLAATIGADIVKQKMAENNGGYKAVNFGYTDDRVYSKLTSDNPIDLVRYQL
                     ANCYMGRAGLINSGGADGGDTDLGDAVRTAVINKRAGGMGLILGRKAFKKSMADGVKL
                     INAVQDVYLDSKVTIA"
     gene            2672..3943
                     /locus_tag="OPV72_003696"
     CDS             2672..3943
                     /locus_tag="OPV72_003696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR9915884.1"
                     /translation="MKTTFKLSFMMFVEWFIWGAWFVPLWLWLNKSGFSAGEIGWSYA
                     CTAIAAILSPILVGSVTDRFFSAQKVLAVLMFAGAVLMYFAAQQTTFAGFFPLLLAYS
                     LTYMPTIALTNSIAFANVPDVERDFPRIRVMGTIGWIASGLACGFLPQMLGYNDISPT
                     NIPLLITAASSALLGVFAFCLPDTPPKSTGKMDIKVMLGLDALVLLRDKNFLVFFFCS
                     FLFAMPLAFYYIFANGYLTEVGMKNATGWMTLGQFSEIFFMLALPFFTKRFGIKKVLL
                     LGLITAAIRYGFFVYGGAETYFTYALLFLGILLHGVSYDFYYVTAYIYVDKKAPVHMR
                     TAAQGLITLCCQGFGSLLGYRLGGVMMEKMFAYPQPVNGLTFNWAGMWTFGAVMIAVI
                     ALLFMIFFRESDKEITAIDDRDIALTQGEVK"
     gene            3940..4944
                     /locus_tag="OPV72_003697"
     CDS             3940..4944
                     /locus_tag="OPV72_003697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HCR9915885.1"
                     /translation="MKAERILGALYGQALGDAMGMPSELWPRTRVKAHFGWIDRFLPG
                     PKENNAACYFNRAEFTDDTAMALCLADALLECEGNIDPEIIGRNILAWAERFDAFNKN
                     VLGPTSKIALNAIRDGKPIAALENNGVTNGAAMRVSPLGCLLPPTNLTAFIAEVALAS
                     SPTHKSDLAVAGAVVVAWAVSRAVNGDTWQSIADSLPAIAHQAQTARITTFSASLSAR
                     LELALNIVRHADGVESASEQLYQIIGAGTSTIESVPCAIAMVELANTDPNRCAVLCAN
                     LGGDTDTIGAMATAICGALHGVSAINPQLKQTLDKVNQLDFARYAVALASYRQRREAL
                     "
     gene            4941..5906
                     /locus_tag="OPV72_003698"
     CDS             4941..5906
                     /locus_tag="OPV72_003698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HCR9915886.1"
                     /translation="MNGARLLTLLPTLHTRRPLTVIGAAVIDIIADAWTLPRRGGDIE
                     LQQQSVNVGGCALNIAVALKRLGIDASNALPLGQGVWAERIRRRLAKEGLSSVIDAVE
                     GDNGWCLALVEPDGERTFMSFSGVENQWNADWLSQLRTPRGSLVYLSGYQLASSCGEP
                     LIQWLETVDDVTPFIDFGPRIGDITDDAMARIMACRPIVSLNRQEAIIAAERAGLATD
                     TRTFGEAWVKRFSAPLVVRHDKDGAWYFSAQSSGVVPAFPATVVDTIGAGDSHAGGVL
                     AGLASGWSLADAVLLGNAVASWVVGHRGGDCAPTREALLLAHKNV"
     gene            complement(5880..6626)
                     /locus_tag="OPV72_003699"
     CDS             complement(5880..6626)
                     /locus_tag="OPV72_003699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCR9915887.1"
                     /translation="MEQAHTRLIAQLNERISAADNTPLYMKFAQTVKDAVRSGILEHG
                     NILPGERDLSQLTGVSRITVRKAMQALEEEGVVTRARGYGTQINNIFEYSLKEARGFS
                     QQVVLRGKKPDTLWVNKRVVSCPDEVAQHLAIPAGSDVFLLKRIRYVDEDAVSIEESW
                     VPAHLIHDVDAIGISLYDYFRRQHIYPQRTRSRVSARMPDDEFQSHIQMDGKVPVLVI
                     KQVALDQQQRPIEYSISYCRSDLYVFVCEE"
     gene            complement(6662..7462)
                     /gene="thiD"
                     /locus_tag="OPV72_003700"
     CDS             complement(6662..7462)
                     /gene="thiD"
                     /locus_tag="OPV72_003700"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HCR9915888.1"
                     /translation="MQRINALTIAGTDPSGGAGIQADLKTFSALGAYGCSVITALVAQ
                     NTCGVQSVYRIEPDFVAAQLDSVFSDVRIDTTKIGMLAETDIVEAVAERLQRHHVRNV
                     VLDTVMLAKSGDPLLSPSAIETLRVRLLPQVSLITPNLPEAAALLDAPHARTEQEMLA
                     QGRALLAMGCEAVLMKGGHLEDAQSPDWLFTREGEQRFSAPRVNTKNTHGTGCTLSAA
                     LAALRPRHRCWGETVNEAKAWLSAALAQADTLEVGKGIGPVHHFHAWW"
     gene            complement(7449..8246)
                     /gene="thiM"
                     /locus_tag="OPV72_003701"
     CDS             complement(7449..8246)
                     /gene="thiM"
                     /locus_tag="OPV72_003701"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HCR9915889.1"
                     /translation="MQPDLHCRTLAAHTLKHFRALSPLTHCMTNDVVQTFTANTLLAL
                     GASPAMVIDPVEARPFAAIANALLINVGTLTASRADAMRAAVESAYDAKTPWTLDPVA
                     VGALEFRRRFCLDLLSLRPAAIRGNASEILALSGMALGGRGVDTTEAALAALPAAQAL
                     ARQIDCIVVVTGEIDYVTNGQRTLSIPGGDPLMTRIVGTGCALSAVVAASCALPGAAL
                     DNVASACCWMKLAGQVAAERSEGPGSFIPAFLDALYHLDMEAANATN"
     regulatory      complement(8278..8374)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            8656..8970
                     /gene="rcnB"
                     /locus_tag="OPV72_003702"
     CDS             8656..8970
                     /gene="rcnB"
                     /locus_tag="OPV72_003702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni(II)/Co(II) efflux transporter accessory
                     subunit RcnB"
                     /protein_id="HCR9915890.1"
                     /translation="MKSKLLPCALLLATSFAWAAPATTGIDQYELKSFIADFTHFKPG
                     DTVPQMYRTDEYNIKQWKLRNLPAPDAGTHWTYMGGAYVLINDTDGKIIKAYDGEIFY
                     HR"
BASE COUNT         2033 a         2568 c         2431 g         2148 t
ORIGIN      
        1 ctgccaaagc agtctaaaga acatttcgat tttatgctat taaaaagtat gtttggtaat
       61 aaatatcagg tttttatctg atattgtggt gtttgaaatt aatactgata actgacgtat
      121 gttcgtcttg ttaatcctcc gtttcgttat taaaggcgct atatcggaaa gcgtctggct
      181 accccttgtg gtttccttgc actctcacaa gcgctactca atgcgcatac cggcatctct
      241 cttgtcgcca tttgccttaa accatgcttc gcttaccgct gcgtacagca ggaagaaaaa
      301 cggtaaagca ataagtgcgc aacgtttcaa ttttcatcct gttctgacct cgctttttca
      361 tttctgctat acactttctg gagattgttg ttcaacctat taaggcataa cggatagcta
      421 actttcccgc cagcttactg atcctcaatg gcaaaagcgc tgataaccag ccgctacgtg
      481 aggccattac gctacttcgc gacgaaggca tacagattca cgttcgggta acctgggaaa
      541 aaggcgacgc gcagcgttac gttgatgaag cccgtagact gggcgttgaa acggtgattg
      601 ccggcggcgg agacggtacc attaatgaag tgtctaccgc gctcatccag atccgcgacg
      661 gcgtagcccc cgcactgggc cttttgccgc tcggcaccgc caacgatttt gccaccagcg
      721 ccggtattcc tgaagcgctg gacaaagcgc tgaaactggc gattgccgga aacgcgatgg
      781 aaattgatat ggccagggtc aatgataaaa cctgttttat caatatggcg acgggcggtt
      841 ttggcacccg cattaccacc gaaacgccgg aaaaacttaa agccgcgttg ggcggcgtct
      901 cctatcttat tcacggtctg atgagaatgg atacgctgac ccctgaccgc tgcgaaatac
      961 gtggcgaaaa ctttcactgg cagggagatg cgctggtgat cggcatcggc aacggtcgtc
     1021 aggccggcgg cgggcagcaa ttatgtccca ccgcgctgat taacgacgga ctgttacagc
     1081 tacggatttt taccggcgaa gaactgctgc cggcgctgtt ttccacactc acgcagtcag
     1141 atgacaatcc gaatattatt gacggcgcct cagcgtggtt tgatattcat gcaccgcatg
     1201 aaatcacgtt caatctggat ggcgaaccac tcagcgggca agaatttcat attgaggtgc
     1261 tgcctggcgc attacgctgt cggctgccgc cagactgccc gttgctacgt taataacacc
     1321 agtcgctggc cggatgcgct cacatccggc ttttcttcgt tgaactcagg cgatggtgac
     1381 tttgctatcc agatagacat cctgtacggc attaatcaac ttcacgccat cagccatcga
     1441 tttcttaaag gctttacgtc ccagaattag tcccattcca ccggctcgtt tgttgatcac
     1501 cgcggtacga accgcgtcgc cgagatcagt gtcaccgccg tccgcgccgc cggagttgat
     1561 aagcccggcg cgtcccatat agcagttcgc caactggtaa cgaaccaaat caatcgggtt
     1621 atcgctggtc agtttgctgt acacgcgatc gtcggtatag ccgaagttga ccgctttata
     1681 accgccatta ttctcggcca ttttctgttt cacaatatcc gcaccaatcg tagcggccag
     1741 atggttggct tgccccgtca ggtcagcgga tacatggtaa tcgacgccgt cttttttaaa
     1801 ggaagaatta cgcaggtaag cccacaatac ggtcaccata cccagctcat gcgcacgctc
     1861 aaaagcggcg gagatctctt caatctggcg acgggactgt tccgaaccga aatagatcgt
     1921 cgcgcctacc gccacggcgc ccatattgaa cgcctgctca acgctggcgt acagggtctg
     1981 atcgtactct gtcggatagc tcaatgtttc gttgtgattc agtttgacca aaaacggaat
     2041 acggtgcgca tagcgccgtg aaaccgaggc cagtacgccg taggtagagg ccacgcagtt
     2101 acagccggcc tcaatcgcca attcaacaat attttttggg tcaaagtagc gcgggttggc
     2161 cgcaaaagaa gcgccggcgg agtgctccac tccctgatcg acgggcagta tcgaaaggta
     2221 tcctgttccc gccaggcgtc cagtattata gagcgtctgc atattacgca gaacggctgg
     2281 tggacgatta ttgtcaatca tcacccggtc aacgtaatcc ttgccgggta gataaagctg
     2341 atcggaagga atggtcatac aacgatgctg taaaaggctg tcggcgtctt tgccaagcaa
     2401 ctgcgcaata tcagtcatag ctatgctccc gtaagttccg atagggtatc ggaaggtgaa
     2461 tagtcctgcc ccgcagattg cgggtcgcaa taagcctggt actgaccgac catttttgcc
     2521 aactttagcg cattttttcg gcgctatctg ctgactcgat tcacgtccga aaaagtgtta
     2581 gatcggtcaa aattaatgct caatggtatt taaaaggtat tattaagtgg tattgtcgtg
     2641 gcgtacctta cctgtcatga aggattcaaa aatgaaaacg acctttaaac tgtcgttcat
     2701 gatgttcgtg gagtggttta tctggggcgc ctggttcgtc cccctgtggc tatggctaaa
     2761 taaaagcggg ttttccgccg gtgaaatagg ctggtcttat gcctgtaccg ccattgcggc
     2821 gatcctgtcg ccgattctgg tcggctccgt taccgaccgt tttttctcag cgcaaaaagt
     2881 cctggcggta ctgatgtttg cgggtgccgt actgatgtat ttcgcggcac agcaaaccac
     2941 ctttgccgga ttctttccgc tgctcctggc ctattcattg acctatatgc cgaccatcgc
     3001 gctgacaaac agcattgcct tcgctaacgt accggacgtt gaacgcgatt ttccacgcat
     3061 tcgcgttatg ggaaccattg ggtggattgc ctccggcctc gcctgtggat tcttgccgca
     3121 aatgttaggc tataacgata tttcccccac caacattcca ctgctcataa ccgccgcaag
     3181 ttcagcgttg ctgggcgtat ttgcgttctg tctgccagac acgccgccaa aaagcaccgg
     3241 caagatggat attaaagtga tgctggggct ggatgcgctg gttctgctgc gcgataaaaa
     3301 ctttctcgtt ttcttcttct gttccttcct gtttgcgatg ccgctggcct tctactacat
     3361 cttcgctaac ggctatctga cagaagtggg aatgaaaaac gccaccggct ggatgacgct
     3421 cggccagttc tctgaaatct tctttatgct ggcgctaccc tttttcacta agcgctttgg
     3481 tattaaaaag gtattattac ttggtcttat taccgccgcg atccgctacg gcttttttgt
     3541 ctatggcggc gcggagacgt acttcactta cgccctgctg ttcctcggta ttttgctgca
     3601 cggcgtaagt tacgatttct actacgtcac cgcctacatt tatgtcgata aaaaagcgcc
     3661 ggttcatatg cgtaccgctg cgcaagggct tatcaccctc tgctgtcagg gattcggcag
     3721 cctgctgggc tatcgtctcg gcggcgtgat gatggaaaaa atgtttgctt atccgcaacc
     3781 ggttaacggt ctgacattca actgggcggg catgtggacg tttggcgcag tgatgattgc
     3841 cgtcatcgcg ctactgttta tgattttctt tcgcgaatcg gacaaagaga tcactgctat
     3901 tgacgatcgc gatattgcgt tgacacaagg ggaagtaaaa tgaaagcaga acgtattctc
     3961 ggtgctcttt acgggcaagc gttaggggat gcgatgggaa tgccctctga gctgtggccg
     4021 agaacgcgcg tcaaagcgca tttcggctgg attgaccgct ttctgcccgg cccaaaagaa
     4081 aataatgccg cctgctattt taaccgcgcg gagtttacgg acgataccgc aatggcgctc
     4141 tgcctggccg acgcgctact cgaatgcgaa ggcaacattg atcccgagat tattgggcgt
     4201 aacatcctcg cctgggcgga acgctttgat gcgttcaata aaaatgtact cggcccgacg
     4261 tcaaaaattg cgctgaatgc gattcgcgac ggcaaaccca tcgcggcgct ggaaaataac
     4321 ggcgtgacta acggcgcggc catgcgcgtt tcgccgttgg gctgcctgtt gccgccaact
     4381 aacctgacag cctttatagc agaagtagcg ttagcctcca gcccgacgca taaatccgat
     4441 ctggcggtgg ctggcgccgt ggttgtcgcc tgggccgtct cgcgagcggt taacggcgac
     4501 acgtggcaaa gtattgccga ctcgctcccc gccatcgccc atcaggcgca gacagcgcgt
     4561 attaccacgt ttagcgcctc gctatcggca cgtctggaac tggcgctaaa cattgtccgc
     4621 cacgccgacg gcgtcgaatc tgccagcgaa cagctctatc agatcatcgg cgcgggaacc
     4681 agcaccattg aatcggttcc ctgcgctatc gccatggtgg agctggcgaa taccgatcct
     4741 aaccgctgtg ccgtgctgtg cgctaacctc ggcggcgata ccgacactat cggcgcgatg
     4801 gctaccgcca tttgcggcgc gttgcacggg gtaagcgcca ttaaccccca gttaaagcaa
     4861 acgctggaca aggttaatca gctggatttt gcgcgctatg ccgttgcgct ggcgagctat
     4921 cgtcaacggc gggaggcact atgaacggcg cacggttgct gacattatta ccgaccctgc
     4981 atacccggcg tccgctcacc gttatcggcg cggcagtgat cgatatcatt gccgacgcct
     5041 ggacgttgcc gcgtcgcgga ggcgatattg aactgcaaca acagagcgtc aatgtcggcg
     5101 gctgtgcgct gaatattgcc gtggcgttga aacgactggg gattgacgcc agcaatgcgc
     5161 tgccgctggg ccagggcgtg tgggcggaga ggattcgccg ccgtctggca aaagagggat
     5221 tatccagcgt gattgacgcg gttgaaggag ataacggctg gtgtctggcg ttagtcgaac
     5281 cggatggcga acgcacgttt atgtctttta gcggcgtgga aaaccagtgg aatgcggact
     5341 ggctgtcgca gctcaggaca ccgcggggca gtcttgtcta cctgtccggc tatcaactgg
     5401 cctcgtcctg tggcgagcca ctgatccagt ggctggaaac cgtcgacgat gtaacgcctt
     5461 ttatcgattt tggcccgcga atcggtgata ttacagacga tgcaatggcg cgcattatgg
     5521 cctgccggcc catcgtatcc ctcaatcgcc aggaagccat catcgccgcg gaacgcgccg
     5581 ggcttgcgac cgatacccgc actttcggcg aagcatgggt aaaacgcttt tccgcgccgc
     5641 tggtggtgcg ccacgataaa gacggagcgt ggtattttag cgcgcaatct tccggcgttg
     5701 tgccagcgtt tccggcaacc gtggtggata ccatcggcgc aggcgacagc catgctggcg
     5761 gcgtgctggc aggactggcg tcaggctggt cgctcgcgga tgccgtactg ctgggaaatg
     5821 cggtggcgag ctgggtggtc gggcatcgcg gcggcgactg cgcgcccacg cgcgaggcgc
     5881 tactcctcgc acacaaaaac gtataggtcg ctacgacaat aactgatgct gtattcaata
     5941 ggccgctgct gctgatcgag cgccacctgc ttaatcacca gcaccggcac tttaccatcc
     6001 atttgaatat gcgactgaaa ctcatcatcc ggcatccggg cgctgacgcg ggatcgggta
     6061 cgctgagggt aaatgtgctg gcgacgaaaa tagtcataca gcgaaatgcc aatcgcgtcg
     6121 acatcatgaa tcagatgcgc gggcacccag gactcttcaa tcgataccgc gtcctcatca
     6181 acataacgaa tgcgtttgag taaaaagacg tcgctgcctg cggggatcgc cagatgctgc
     6241 gcgacctcat ccggacaact taccacgcgt ttgttaaccc atagcgtatc cggttttttg
     6301 ccgcgcaaga caacctgctg agaaaatccc cgcgcctctt tcagggaata ttcaaagata
     6361 ttattgattt gcgtaccgta gccgcgggcg cgcgtgacga ccccctcttc ttccagcgcc
     6421 tgcatcgctt ttcgtaccgt gatgcgcgag acgccggtaa gctggctgag atcgcgttcg
     6481 ccaggcaaaa tattaccgtg ctcaagaata ccgctgcgca cggcatcctt taccgtctgg
     6541 gcgaatttca tgtatagcgg cgtattatcc gccgctgaaa ttcgttcatt cagttgcgcg
     6601 atgagccggg tatgcgcttg ttccatttat ctttcctgac gacgggtctg taggcagtat
     6661 actaccacca cgcgtggaaa tgatgtaccg gaccaatgcc cttccccact tccagcgtgt
     6721 ccgcctgcgc cagcgccgcc gaaagccatg ccttcgcctc gtttaccgtc tctccccaac
     6781 agcgatgccg gggccgtaac gccgccagcg ccgccgacag cgtacagccc gtcccatgcg
     6841 tatttttggt gttcacacgc ggcgcgctaa aacgttgctc gccctcacgg gtaaagagcc
     6901 agtccgggct ttgcgcatcc tctaaatgcc cgcctttcat caataccgct tcacacccca
     6961 tcgccagtaa cgcccgcccc tgcgccagca tctcctgttc cgtacgtgca tggggcgcat
     7021 ccagcaacgc tgcggcttcc ggcaaattag gcgtaatcag cgatacctgt ggcaacagcc
     7081 ggacgcgtaa tgtttctatc gcagagggcg agagcagcgg atcgccgctt ttcgccagca
     7141 tcaccgtatc cagcaccaca ttacgtacat gatgacgctg tagtcgctcc gccacggcct
     7201 cgacaatatc ggtttccgcc agcatcccga tttttgtggt atcaatgcgc acatcgctga
     7261 acacggaatc aagttgagcg gcgacaaagt ccggctctat ccggtacacc gactgtacgc
     7321 cacaggtatt ttgcgccacc agcgcggtga tgaccgaaca gccatatgcg cccagcgcgg
     7381 aaaaggtctt gagatccgcc tggataccgg ccccgccgct gggatcggtg ccggcaatcg
     7441 tcagcgcgtt aattcgttgc attggccgcc tccatatcca gatgatagag cgcatcaaga
     7501 aaagccggga tgaagctgcc cggtccttcg ctacgctctg ccgcgacctg tccagccagt
     7561 ttcatccagc agcaggccga cgcgacattg tccagcgcgg cgcccggtaa cgcgcaactg
     7621 gcggcgacaa ccgccgacaa cgcgcagccg gtgcctacaa tgcgagtcat taacggatcg
     7681 ccgccgggaa tgctcagcgt gcgctgacca ttagtgacgt aatctatctc tccggtaacc
     7741 acaacgatgc agtctatctg acgcgccagc gcctgcgccg caggcagtgc ggccaacgcc
     7801 gcctcggtgg tatctacgcc gcgtccgccc agcgccatgc cggataacgc caggatttcc
     7861 gaggcgttgc cgcgtattgc cgccgggcgc agggacaaga gatccaggca aaatcgccga
     7921 cgaaattcca gcgcgcccac cgcgacagga tcaagcgtcc acggcgtttt ggcatcataa
     7981 gcgctttcta ccgccgcacg catcgcgtca gcgcgtgagg cagttaatgt tccgacatta
     8041 atcagcaagg cgttggcgat ggcggcaaac ggtctggcct cgacaggatc aatcaccatg
     8101 gcgggtgaag cgcccagcgc cagcaacgta ttggcggtaa acgtttgtac gacgtcattc
     8161 gtcatacagt gcgtaagcgg ggagagcgcg cgaaagtgtt ttaacgtatg cgccgcaagc
     8221 gtgcggcagt gcaggtcagg ctgcatggtt cagctcctgc ccgcgtgaag aagggacacg
     8281 agcagtgtca gacttcccta cgctggcatt atccagatca ggtggtacgg gtatttctca
     8341 gccttcacaa agaagggcac cccgagtcgt caagccccac cgtgttaagc ggggtttcgc
     8401 tattaagcat actgtctgtg ccagacaatg taaatttaca gtcagcggcg gacgataatt
     8461 ttagcgttat cagatagttc tcaaaaccta ttcggttctg gcaaacttgc tggcggatat
     8521 gttgctgcac gacgctttcg tttacacttt ttacgaaaag gggcgtgaga taacaaaata
     8581 gcgcttgtca gatacgccac cagcagaaat gatacacacg atgttaactg acccgcatat
     8641 gtggagggta aaagtatgaa aagtaagttg ctgccttgcg cgctgttgct tgcaaccagt
     8701 tttgcatggg ccgcccccgc gacaacgggc attgatcaat atgagttaaa aagctttatc
     8761 gccgacttca cccacttcaa gcccggcgat accgttccgc aaatgtaccg caccgatgag
     8821 tataatatta aacagtggaa attacgtaat ctgcccgcgc cagatgccgg tactcactgg
     8881 acctatatgg gcggcgcgta tgtactgatt aacgataccg atggaaaaat catcaaagcc
     8941 tatgatggcg agatttttta tcatcgataa aaaaagcccc ctcatccaga gggggaaata
     9001 cagccccatg ttactttttt attagccctt aatcactcta tccccttcaa acctcctttt
     9061 tgttgactgc cttcactacc cgattcgctc tggatctcgc ccttttgaaa ctaccgcata
     9121 ccacattaga atttattgca gaaagattgt catcccggtc acttattatt gtaagtgacc
//
LOCUS       DAJVBX010000187         8940 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.187, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000187 DAJVBX010000000
VERSION     DAJVBX010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 8940)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8940)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8940
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.187"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            150..1793
                     /locus_tag="OPV72_003703"
                     /pseudo
     CDS             150..1793
                     /locus_tag="OPV72_003703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462067.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing protein"
     gene            1878..2165
                     /locus_tag="OPV72_003704"
     CDS             1878..2165
                     /locus_tag="OPV72_003704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2623 domain-containing protein"
                     /protein_id="HCR9915891.1"
                     /translation="MNNHFGKGLMAGLHAPYAYSAHHAVNFCSEYKRGFVLGFTHRMF
                     EKTGDRQLSAWEAGILTRRYGLDKEMVMDFFKENHSGMAVRFFMAGYRLEG"
     gene            2355..3473
                     /gene="hybO"
                     /locus_tag="OPV72_003705"
     CDS             2355..3473
                     /gene="hybO"
                     /locus_tag="OPV72_003705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 2 small subunit"
                     /protein_id="HCR9915892.1"
                     /translation="MTGDNTLITSHGINRRDFMKLCAALAATMGLSSKAAAEMAESVS
                     NPQRPPVIWIGAQECTGCTESLLRATHPTVENLVLETISLEYHEVLSAAFGHQVEENK
                     HNALEKYKGQYVLVVDGSIPLKDNGIYCMVAGEPIVDHIRKAADGAAAIIAIGSCSAW
                     GGVAAAGVNPTGAVSLQEVLPGKTVINIPGCPPNPHNFLATVAHIITYGTPPKLDAKN
                     RPTFAYGRLIHEHCERRPHFDAGRFAKEFGDEGHRQGWCLYHLGCKGPETWGNCSTLQ
                     FCDVGGVWPVAIGHPCYGCNEEGIGFHKGIHQLAHVENQTPRSEKPDVNMKEGGNISA
                     GAVGLLGGVVGLVAGVSVMAVRELGRQQKKDNADSRGE"
     gene            3476..4462
                     /gene="hybA"
                     /locus_tag="OPV72_003706"
     CDS             3476..4462
                     /gene="hybA"
                     /locus_tag="OPV72_003706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 2 operon protein HybA"
                     /protein_id="HCR9915893.1"
                     /translation="MNRRDFIKAASGGALLLGAAPSVSHAAAENRPPIPGSLGMLYDS
                     TLCVGCQACVTKCQDINFPARNPEGEQTWSNNDKLSPYTNNIIQVWRSGTGVNKDQEE
                     NGYAYIKKQCMHCVDPNCVSVCPVSALKKDPKTGIVHYDKDVCTGCRYCMVACPYNVP
                     KYDYNNPFGALHKCELCNQKGVERLDKGGLPGCVEVCPAGAVIFGTREELMAEAKKRL
                     ALKPGSEYHYPRQTLKTDDTYLHTVPKYYPHLYGEKEGGGTQVLVLTGVPYEDLDLPK
                     LDDLSTGARSEHVQHTLYKGMILPLAALAGLTVLVRRNSKNDHHDGGDDHES"
     gene            4452..5630
                     /gene="hybB"
                     /locus_tag="OPV72_003707"
     CDS             4452..5630
                     /gene="hybB"
                     /locus_tag="OPV72_003707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni/Fe-hydrogenase cytochrome b subunit"
                     /protein_id="HCR9915894.1"
                     /translation="MSHDPKPLGGKIISKPVIIFGPLIVLCMLLIVKRLVFGLGSVSD
                     LNGGFPWGVWIAFDLLIGTGFACGGWALAWAVYVFNRGQYHPLVRPALLASLFGYSLG
                     GLSITIDVGRYWNLPYFYIPGHFNVNSVLFETAVCMTIYIGVMALEFAPALFERLGWK
                     VSLKRLNKVMFFIIALGALLPTMHQSSMGSLMISAGYKVHPLWQSYEMLPLFSVLTAF
                     IMGFSIVIFEGALVQAGLKGNGPDEKNLFVKLTNTISVLLAIFVVLRFGELIYRDKLS
                     YAFAGDFYSAMFWIEVVLMVFPLVVLRVAKLRNDSRMLYLSALSALLGCATWRLTYSL
                     VAFNPGGGYHYFPTWEELLISIGFVAIEICAYIVLIRLLPILPPLKQNDHNRHEASKA
                     "
     gene            5627..7330
                     /gene="hybC"
                     /locus_tag="OPV72_003708"
     CDS             5627..7330
                     /gene="hybC"
                     /locus_tag="OPV72_003708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 2 large subunit"
                     /protein_id="HCR9915895.1"
                     /translation="MSQRITIDPVTRIEGHLRIDCEIENGVVSKAWASGTMWRGMEEI
                     VKNRDPRDAWMIVQRICGVCTTTHAISSVRAAESALNIDVPVNAQYIRNIILAAHTTH
                     DHIVHFYQLSALDWVDITSALKADPEKASAMLDGVSSWHLNSAQEFTKVQNKIKDLVA
                     SGQLGIFANGYWGHPAMQLPPEVNLIAVAHYLQALECQRDANRVVALLGGKSPHIQNL
                     AVGGVANPINLDSIGTLNLERLMYIKSFIDKLSDFVEQVYKVDTAVIAAYYPEWLERG
                     KGAVNYLSAPEFPTDGKNGSFLFPGGYITNADLSTYRPITSHSDEFLIKGIQESAKHA
                     WYKDEAPQAPWEGTTIPAYDGWSDDGKYSWVKSPTFYGKTVEVGPLANMLCKLAAGRE
                     STQTKLNEIIALYQKLTGKTLEMAQLHSTLGRIIGRTVHCCELQNVLQDQYNALIVNI
                     GKGDYTTFVKPNIQATGEFKGVGFLEAPRGMLSHWMVIKDGIISNYQAVVPSTWNSGP
                     RNFNDDVGPYEQSLVGTPIADPAKPLEVVRTIHSFDPCMACAVHVVDADGNEVVSVKV
                     L"
     gene            7330..7824
                     /locus_tag="OPV72_003709"
     CDS             7330..7824
                     /locus_tag="OPV72_003709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016157468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HyaD/HybD family hydrogenase maturation
                     endopeptidase"
                     /protein_id="HCR9915896.1"
                     /translation="MRILVLGVGNILLTDEAIGVRIVEALEQRYTLSDFVEILDGGTA
                     GMELLGDMANRDHLIIADAIVSKKNAPGTIMVLRDDEVPALFTNKISPHQLGLADVLS
                     ALRFTGEFPKKLTLVGVIPQSLEPHIGLTPTVEAMIEPALEQVLAALRESGVEAIPKE
                     TAHV"
     gene            7817..8305
                     /gene="hybE"
                     /locus_tag="OPV72_003710"
     CDS             7817..8305
                     /gene="hybE"
                     /locus_tag="OPV72_003710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase-2 assembly chaperone"
                     /protein_id="HCR9915897.1"
                     /translation="MSETFSGFDTAPVARVQAAFEEIAHRSMHDLSFLHPTMPVHVSD
                     FTLFEGQWTGTVITPWMLSALIFPGPDQIWPGRTVGEKLGLQLPYGTMTFTVGELEGV
                     SQYLACSLMSPLSRSLSPEEGVRLADDCARMLLSLPVSNPDAPQTSRRALLFGRRSCE
                     NA"
     gene            8298..8639
                     /gene="hypA"
                     /locus_tag="OPV72_003711"
     CDS             8298..8639
                     /gene="hypA"
                     /locus_tag="OPV72_003711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation nickel metallochaperone
                     HypA"
                     /protein_id="HCR9915898.1"
                     /translation="MHELSLCQSAVEIIQQQAEQHGVARVTGVWLEIGALSCVEERAV
                     RFSFDIACQGTLAQGCELHIDYRPAQAWCWDCSQVVEILRHDAQCPHCHGDRLRVDTG
                     DSLKVKSIEVE"
     gene            8667..8915
                     /gene="hybG"
                     /locus_tag="OPV72_003712"
     CDS             8667..8915
                     /gene="hybG"
                     /locus_tag="OPV72_003712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation factor HybG"
                     /protein_id="HCR9915899.1"
                     /translation="MCIGVPGQVLAVGDDIHQLAQVEVCGIKRDVNIALICEGKPADL
                     IGQWVLVHVGFAMSIIDEDEAKATLDALRRMEYDITSA"
BASE COUNT         2015 a         2245 c         2564 g         2116 t
ORIGIN      
        1 cgttcacaga tatataacat ctacgggtac gtaaacggcg ataactgtaa aaaaatggag
       61 aatgcattat atattctccg cgccttgccg ataacgagag tgcgtcatcg tctgatgact
      121 aatctcttat attcagcaag gaaattcata tgcgtttgct gcaaaacttt actattcgta
      181 tggtcatgct gacgatactg ggactttttt gtctactctg gtcgggggtg ggtttataca
      241 gcgtccatgc tttatccgaa gtttcggaag gaaatgatat tgaccggcat cttgtgcggc
      301 aaatgacggt gctaagccag ggtaacgatc aatatttccg ctttgttacc cgccttagcc
      361 gcgcgatgga tgtaaaaatc ggcggcggca cgcccgattt tgcgcccgcc cggcagtcgc
      421 tcgagaatat gcgtcagaag ctggaggaga tgaaagcgct atcgccaggg ccgatgaacc
      481 ctgatatctc aagggcggtg ttgtccaact ggcaggcctt gctggagaaa ggcgtcattc
      541 ctcaaatgca actggcgcag caaggatcgc tgaccgcctg gagcgaacat gccagtacgg
      601 tcacgcctgc acttagccgc gcgttcggcg ccagcgcgga acggtttaat catgaagctg
      661 gcgccatgct ggataacacc cgtgtgatgg tcgatggtaa aacctatacc atccgcatcc
      721 tgcttattac ggcggtgatt ctgggcattg ccatcctgat ttttaccgat cgctatttgg
      781 ttgcaatgat ggtgaaaccg ctggagcgca tccgtcagca gtttcagcgt atcgcgcaag
      841 gcgatcttag ccagccgatt gaagcgttgg ggcgtaactg cgtaggccgg ttggtgccgc
      901 tactgcgcgc gatgcaggac agtttacgcg aagccgtcag tacgatccgc gccggaagcg
      961 acaatatctg gcgcggcgcg acggaaattt ctaccggtaa taacgatctc tcttcccgaa
     1021 cggaagaaca ggccgtcgcg ctggaagaaa ctgccgccag catggaacag cttaccgcaa
     1081 cggtaaaaat gaacgccgaa cacgctcgcc aggcgagtca gcttgcggat gccgcctcgc
     1141 taacggcagg aaaaggcggt gaactggttt ccgatgtggt agaaacaatg aacggtattt
     1201 ccgccagttc gcagcagatc gccgaaatta ctaccgtgat taatagtatt gctttccaga
     1261 ccaatattct ggccttgaac gcagcggtag aagcggccag agcgggcgag cagggacgcg
     1321 gcttcgcggt ggtcgccggt gaggtacgta acctggccag ccgcagcgcg ggggcggcga
     1381 aagaaattga agctttaatt ggcgaatcgg cacgtcgcgt agcgcagggc gcgcagttgg
     1441 tctaggagac cggcgcgacg atggacgcca tcctgcgcgg cgtcacggaa gtgacgacga
     1501 ttatgaaaca gatcgcgtcc gcctccgaag agcagagtaa aggtatctct caggttggcg
     1561 tggcgatcac gcaaatggat agcgttacgc aacaaaacgc cgcgctggtt gagcaggttt
     1621 ccgccgcggc ggcggcgctg gaacggcaga cggaggattt gcaacgctcc gtacagcagt
     1681 tccggctttc cgctagtgag ccgcaacaac gcgtaacgac gaaagcggcg cctggcgttc
     1741 agagaatggc gtcggctccc gcacagtcta ctgatgaatg ggttgccttc tgatgtgaag
     1801 caaaaaagcg cgtaatgcgc tggccttcat ttaaccagtt gctatataat ttattatata
     1861 gcgactaagg aggtcagatg aataatcatt ttgggaaagg gttaatggcc gggttgcacg
     1921 cgccatatgc atatagcgcg catcatgcgg tgaatttctg ttctgagtat aaacgtggct
     1981 ttgtattggg ttttacacac cgtatgttcg aaaagaccgg cgatcgtcaa cttagcgcgt
     2041 gggaggccgg aattctgacg cgtcgctatg gtctggataa agaaatggtg atggatttct
     2101 ttaaagagaa tcattccggg atggcggttc gcttctttat ggctggttat cgactcgaag
     2161 gttgatccaa caggggtatt atcttgcttt aattaattac actatcgcct cttcccttcg
     2221 ttttactgtt ccgtcgaagt attatggcgc acataaccat aaaaaaagtg tggtaaatgg
     2281 cgtaccgatc gcaataactt cttcgcgaac agtgcaaaat aaaagctagg tcttcgtaac
     2341 ggaataacta taaaatgact ggagataata ctctcatcac ttctcacggc attaaccgtc
     2401 gtgatttcat gaagctttgt gcagcactgg ccgctactat ggggctcagt agcaaagccg
     2461 ccgcagaaat ggcagaatcg gtatccaatc cacagcgtcc gcccgttatc tggattggcg
     2521 ctcaggagtg taccggttgt accgaatcac tgcttcgtgc tacacaccca accgttgaaa
     2581 acctcgttct ggagactatc tctctggaat accacgaggt actttccgcc gcattcggtc
     2641 accaggtcga agaaaacaaa cataacgctc tggagaagta taaagggcaa tatgttctgg
     2701 tggtggatgg ttctatccca ctaaaagata acggtatcta ctgcatggtt gccggcgagc
     2761 cgatcgtgga tcacatccgc aaagccgccg acggcgcagc cgcgattatc gctatcggtt
     2821 cctgctcggc atggggcggc gttgctgcgg ctggcgtaaa cccaaccggc gctgtcagtc
     2881 tgcaggaagt cttaccgggc aaaacggtta tcaatattcc aggttgtccg ccaaacccgc
     2941 ataacttcct ggcgaccgtc gcgcatatca tcacttacgg cacgccgccg aagctggatg
     3001 cgaaaaatcg tccaaccttt gcctatggcc gtctgatcca tgagcattgc gaacgtcgtc
     3061 cacacttcga cgcaggccgt tttgccaaag aatttggcga cgaaggccac cgtcagggct
     3121 ggtgcctcta ccatcttggc tgtaaagggc cggaaacctg gggcaactgt tctacattac
     3181 agttctgtga cgttggcggc gtctggccag tggcgatcgg tcatccttgc tatggctgta
     3241 acgaagaagg tatcggcttc cataagggca ttcaccagct tgctcatgtc gaaaaccaaa
     3301 ctccgcgttc agagaaacct gacgtcaata tgaaagaagg cggcaatatc tctgcgggcg
     3361 ctgtcggtct gcttggcggc gtagtcggtc tggttgccgg cgtcagcgtg atggcggtac
     3421 gtgaactggg gcgtcagcaa aagaaagata acgctgactc acggggagaa taaccgtgaa
     3481 cagacgtgac tttattaaag cagcctccgg tggagcattg ctgttgggcg ccgcgccgtc
     3541 tgtcagccat gcggctgcag aaaaccgtcc gccaattcca ggttcgctgg gcatgctgta
     3601 tgactccact ctgtgcgtgg gctgtcaggc ctgcgtcaca aagtgtcagg atatcaactt
     3661 cccggcgcgt aacccggaag gggagcagac ctggtcgaac aacgacaaac tgtcgccgta
     3721 taccaataac attatccagg tatggcgtag cggcacgggc gtgaacaaag atcaggaaga
     3781 gaacggctat gcctacatca agaaacagtg tatgcactgc gtcgatccta actgcgtttc
     3841 cgtttgtccg gtgtcggcgc tgaaaaaaga tccgaaaacc ggcatcgtcc actatgacaa
     3901 agatgtctgc accggctgcc gttactgtat ggtcgcctgt ccgtacaacg tacctaagta
     3961 cgactacaac aacccgtttg gcgcgcttca caagtgtgag ttgtgtaacc agaaaggcgt
     4021 tgagcgtctg gataaaggcg gtttgcctgg gtgtgtggaa gtttgtccgg caggggccgt
     4081 cattttcggt actcgtgaag agctaatggc ggaagcgaaa aaacgtctgg ccctcaaacc
     4141 aggcagtgaa tatcactatc cgcgccagac gttgaaaacg gacgacacct atctgcatac
     4201 ggtgcctaaa tactacccac acctctacgg tgaaaaagag ggcggtggta ctcaggtgct
     4261 ggtgctgaca ggcgttcctt atgaagattt ggatctgccg aagctggatg acctttcaac
     4321 cggagcgcgc tccgagcatg ttcaacacac gctttataaa ggcatgatac tacccctggc
     4381 tgcgctggcg ggcttaaccg tgctggttcg tcgtaatagc aaaaacgacc atcacgatgg
     4441 aggagacgat catgagtcat gatccaaaac cgctgggcgg aaaaatcatc agtaaaccgg
     4501 tcattatttt tggaccgtta atcgtcctgt gtatgctcct tatcgtgaag cgtctggtct
     4561 tcgggttggg ctccgtttcc gacctgaacg gcggtttccc gtggggcgtc tggattgcct
     4621 ttgacctgtt gatcggcacc ggctttgcct gcggcggttg ggcgttggca tgggcggtgt
     4681 atgtctttaa ccgtgggcaa taccatccgt tggtgcgccc ggcattgctg gcaagcttgt
     4741 ttggttactc gctgggcggc ctgtcgatca ctatcgacgt cggtcgttac tggaacctgc
     4801 cgtacttcta cattccaggt cacttcaacg tgaactcggt actgtttgag acggcggtct
     4861 gtatgaccat ctacatcggc gtgatggcgc tggagtttgc gcctgccttg tttgaacgtc
     4921 tgggctggaa agtgtcgctc aagcgtctga ataaggtgat gttctttatt atcgcgctgg
     4981 gcgcgctgct gccgacgatg caccagtcct caatggggtc attgatgatc tcggcgggct
     5041 ataaagtgca tccgctatgg caaagctatg aaatgctgcc gctgttctcg gttctgaccg
     5101 cgtttatcat gggcttctcc attgtcatat ttgagggggc gctggttcag gcaggcctga
     5161 aaggaaacgg tccggatgag aaaaatttgt ttgttaagct gacgaatacc atcagcgtgc
     5221 tgctggcgat tttcgtcgtc ctgcgctttg gcgaactgat ttatcgcgac aagctgtcct
     5281 atgcgtttgc cggcgatttt tactccgcta tgttctggat tgaagtcgtc ctgatggtct
     5341 tcccgttagt ggtgctgcgt gtggcgaaac tgcgtaatga ctctcgtatg ctgtacctgt
     5401 cggcgctgag cgcgctgttg ggttgcgcga cgtggcgtct gacctattcg ctggtggcat
     5461 tcaacccggg tggcggctac cactacttcc caacctggga agaattgttg atttctattg
     5521 gttttgtggc tattgagatt tgtgcataca tcgtactcat tcgtctactg ccgatacttc
     5581 ctcctttaaa acaaaacgat cataatcgtc atgaggcgag caaagcatga gccagagaat
     5641 tactattgat ccggtaaccc gtattgaggg tcatttacgc attgactgcg aaattgagaa
     5701 cggcgtcgta tccaaagcat gggcgtccgg caccatgtgg cgcggtatgg aagagatcgt
     5761 gaagaaccgc gatccgcgcg atgcgtggat gattgtgcaa cgtatttgcg gcgtttgtac
     5821 gacaactcac gcgatctcct ccgttcgtgc ggcggaaagc gcgctgaata ttgatgttcc
     5881 cgtcaacgcg cagtatatcc gtaatattat tctggcggcg cataccaccc atgaccacat
     5941 tgtccatttc taccagctct ctgcgctgga ctgggtggac attacctctg cgctgaaagc
     6001 cgatccggaa aaagcttctg cgatgctgga tggcgtgtcg agctggcacc tgaacagcgc
     6061 gcaagagttc acgaaagttc agaacaagat caaggatctt gtcgctagcg gtcagttagg
     6121 tattttcgcc aatggctact gggggcaccc ggcaatgcag ttaccgccgg aggtcaacct
     6181 gattgcggtc gcccactatc tgcaggcgct ggaatgtcag cgtgacgcta accgcgtggt
     6241 ggcgttgctg ggcggtaaat cgccgcatat ccagaacctg gcggtcggtg gggtggcgaa
     6301 cccgatcaat ctcgacagca tcggtacgtt gaaccttgaa cgcctgatgt acatcaaatc
     6361 gtttatcgat aagctgagcg attttgtcga gcaggtgtat aaagtggata ccgcagtcat
     6421 cgcggcctac tatccggaat ggctggagcg cggcaaaggc gcggtgaact acctgagcgc
     6481 gccggaattc ccgaccgacg gtaaaaacgg cagtttcctg ttcccgggcg gttacattac
     6541 caatgccgat ctgtcgacat accgtccgat cacctctcac tccgatgaat tcctgattaa
     6601 aggtattcag gagagcgcga agcacgcctg gtataaagat gaagcgccgc aggcgccgtg
     6661 ggaaggcacc acgattccgg cttacgacgg ttggtcggat gacggtaaat actcatgggt
     6721 caagtcgccg acattctacg gcaaaaccgt cgaagtcggg ccgctggcga acatgctatg
     6781 taaactggcc gcaggtcgtg aatccacgca gaccaagctc aatgaaatca ttgcgcttta
     6841 tcagaagctg accggcaaaa cgctggaaat ggcgcaactt cactctacgc tgggtcgtat
     6901 catcgggcgt accgttcact gttgtgaact gcaaaacgta ttgcaggatc aatacaacgc
     6961 gctgattgta aatatcggca aaggcgatta caccacgttt gtgaagccga acattcaggc
     7021 gacgggcgag ttcaaaggcg tgggcttcct ggaggcgccg cgcggtatgc tgtctcactg
     7081 gatggtgatt aaagacggta ttatcagtaa ctatcaggca gtggtgccat cgacctggaa
     7141 ctcaggtccg cgtaacttca acgatgacgt ggggccgtac gaacagtcgc tggtcggtac
     7201 gccgatcgcc gatccggcga agccgctgga agtggtacgt accatccact ccttcgaccc
     7261 ttgcatggcg tgcgcggtgc acgtggtgga cgccgatggc aatgaagtgg tctcggtgaa
     7321 ggttttgtaa tgcggatatt agtcttaggg gtcggcaata ttttgctgac cgatgaagcc
     7381 atcggggtac gtattgttga agcgttagag caacgataca ccctgtcgga tttcgttgag
     7441 attctggatg gcggtacggc gggaatggaa cttcttggcg atatggcgaa tcgggatcat
     7501 ttgatcattg ccgacgccat cgtgtcgaaa aagaacgcgc cgggaaccat tatggtactg
     7561 cgcgacgatg aagttccggc gctgttcacc aacaaaatct ccccccatca gcttggactg
     7621 gccgacgtat tgtcggccct ccgctttacc ggcgagtttc cgaagaagtt gaccctggtc
     7681 ggcgttattc cacagtcgct ggaaccgcac atcggcttaa cgccaaccgt cgaggcgatg
     7741 attgaacctg cgcttgagca ggttcttgct gcgctgcgtg aatccggcgt cgaagcaatt
     7801 cctaaggaga cggcgcatgt ctgaaacgtt ttccggattc gacacggcgc ccgtcgcccg
     7861 ggttcaggcg gcgtttgaag agatagccca tcgttcgatg cacgatcttt cgtttctgca
     7921 tccgactatg cctgtgcatg tctctgattt tacgttgttt gaaggacaat ggacgggcac
     7981 ggtaattacg ccgtggatgt taagcgcatt aatcttccct ggcccggacc agatctggcc
     8041 cgggcgtacc gtcggtgaaa aactcggtct gcaactgcct tatggcacga tgacctttac
     8101 cgttggcgaa ctggaaggcg tttcacaata tcttgcctgc tcgttgatgt cgccgctttc
     8161 ccgtagcctg tcgccggaag agggcgtccg gctggcggat gactgcgcgc ggatgctgtt
     8221 atccctgccg gtaagcaatc ctgatgcgcc gcagacaagc cggcgtgcgt tgctgtttgg
     8281 ccgtcggagc tgtgagaatg catgagctgt ctctttgcca aagcgccgtt gaaattattc
     8341 agcagcaggc agaacagcac ggcgtggcgc gcgtcaccgg cgtatggctg gagataggcg
     8401 cgctttcgtg cgttgaagag cgcgcggttc gtttcagctt tgacatcgcc tgccagggga
     8461 ctttagcgca agggtgcgaa ttgcacatcg actacagacc ggcccaggcc tggtgctggg
     8521 attgcagtca ggtggtggaa attctcaggc atgacgcgca atgtccgcat tgtcatggcg
     8581 atcgcctgcg ggtggatacc ggcgattcgt tgaaagtaaa aagtattgag gtcgaataac
     8641 ccgcatttta tttcaggtgg ttaattatgt gtattggcgt ccccggtcag gtgctggccg
     8701 tcggagatga tattcaccag cttgcgcagg tggaagtgtg tggcatcaaa cgtgatgtca
     8761 atattgctct gatttgtgaa ggtaagccag ccgatctgat agggcaatgg gtattggtac
     8821 acgttggttt tgcgatgagc atcattgacg aagacgaagc gaaagccacg ttagatgcgc
     8881 tgcgccgcat ggagtacgac atcaccagcg cgtgatccct taatcacctc tattatatcg
//
LOCUS       DAJVBX010000188         8903 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.188, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000188 DAJVBX010000000
VERSION     DAJVBX010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 8903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8903
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.188"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(75..1439)
                     /gene="tdcG"
                     /locus_tag="OPV72_003713"
     CDS             complement(75..1439)
                     /gene="tdcG"
                     /locus_tag="OPV72_003713"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HCR9915900.1"
                     /translation="MISAFDIFKIGIGPSSSHTVGPMNAGKCFIDRLIDSGDLPRTTR
                     ITVDLYGSLSLTGKGHATDTAIIMGLAGNTPQDVNIDSIPAFIQEVARSSRLSVAGGA
                     HVVDFPVADSILFHAETLARHENGMRITAWHGQTPLLHKTYYSIGGGFIVEEERFGQS
                     HDVEKSVPYDFHSASELLTLCERQGLSVSGLMMQNELALRSKEQIDAGFARIWQVMAT
                     GIERGMNTEGVLPGPLNVPRRAVALRRLLVSSDNLSRDPMNVIDWINMFALAVSEENA
                     AGGRVVTALTNGACGIIPAVLAYYDKFRRPVNANSIARYLLSAGAIGMLYKMNASISG
                     AEVGCQGEVGVACSMAAAGLTELLGGSPAQVCIAAEIAMEHNLGLTCDPVAGQVQIPC
                     IERNAINAVKAVNAARMALRRTSEPRVSLDKVIETMYETGKDMNDKYRETSRGGLAIK
                     VVCG"
     gene            complement(1509..3803)
                     /gene="pflB"
                     /locus_tag="OPV72_003714"
     CDS             complement(1509..3803)
                     /gene="pflB"
                     /locus_tag="OPV72_003714"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HCR9915901.1"
                     /translation="MKVNIDTSDMLYAEAWRDFKGTDWKEEINVCDFIQHNYTPYEGD
                     ESFLADATPATTALWEKVMAGIRIENATHAPVDFDTNIATTITAHDAGYIEKELEKIV
                     GLQTDKPLKRALHPFGGVNMIKSSFHAYGREMDADFEYTFTDLRKTHNQGVFDVYSPD
                     MLRCRKSSVLTGLPDGYGRGRIIGDYRRVALYGIRYLVRERELQFADLQSNLERGQNL
                     EATIRLREELAEHRRALLQMQEMAAKYGYDISRPARNAQEAVQWLYFAYLAAVKSQNG
                     GAMSLGRTASFLDIYIERDFNAGLLTEQQAQELIDHFIMKIRMVRFLRTPEFDSLFSG
                     DPIWATEVIGGMGLDGRTLVTKNSFRYLHTLHTMGPAPEPNLTILWSEALPVAFKKYA
                     AQVSIVTSSLQYENDDLMRTDFNSDDYAIACCVSPMVIGKQMQFFGARANLAKTLLYA
                     INGGVDEKLKIQVGPKTAPLTDEVLDYDAVMESLDHFMDWLAVQYISALNIIHYMHDK
                     YSYEASLMALHDRDVYRTMACGIAGLSVAADSLSAIRYAQVKPIRDENGLAIDFAIEG
                     EYPQYGNNDERVDSIACDLVKRFMQKISVLPTYRNAVPTQSILTITSNVVYGQKTGNT
                     PDGRRAGTPFAPGANPMHGRDRKGAVASLTSVAKLPFTYAKDGISYTFSIVPAALGKE
                     DAVRKTNLVGLLDGYFHHEAQVEGGQHLNVNVMNREMLLDAIEHPENYPNLTIRVSGY
                     AVRFNALTREQQQDVISRTFTQAM"
     gene            complement(3837..5045)
                     /gene="tdcD"
                     /locus_tag="OPV72_003715"
     CDS             complement(3837..5045)
                     /gene="tdcD"
                     /locus_tag="OPV72_003715"
                     /EC_number="2.7.2.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propionate kinase"
                     /protein_id="HCR9915902.1"
                     /translation="MNEFPVVLVINCGSSSIKFSVLDVATCDVLMAGIADGMNTENAF
                     LSINGDKPINLSHSNYEDALKAIAFELEKRDLTDSVALIGHRIAHDGELFTQSVIITD
                     EIIDNIRRVSPLAPLHNYANLSGIDAARRLFPAVRQVAVFDTSFHQTLAPEAYLYGLP
                     WEYFSSLGVRRYGFHGTSHRYVSRRAYELLDLDEKNSGLIVAHLGNGASICAVRNGQS
                     VDTSMGMTPLEGLMMGTRSGDVDFGAMAWIAKETGQTLSDLERVVNKESGLLGISGLS
                     SDLRVLEKAWHEGHERARLAIKTFVHRIARHIAGHAASLHRLDGIIFTGGIGENSVLI
                     RQLVIEHLGVLGLTLDVEMNKQPNSHGERIISVNPSQVICAVIPTNEEKMIALDAIHL
                     GNVKAPVEFA"
     gene            complement(5112..6442)
                     /gene="tdcC"
                     /locus_tag="OPV72_003716"
                     /pseudo
     CDS             complement(5112..6442)
                     /gene="tdcC"
                     /locus_tag="OPV72_003716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462157.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine transporter TdcC"
     gene            complement(6463..7452)
                     /gene="tdcB"
                     /locus_tag="OPV72_003717"
     CDS             complement(6463..7452)
                     /gene="tdcB"
                     /locus_tag="OPV72_003717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional threonine ammonia-lyase/L-serine
                     ammonia-lyase TdcB"
                     /protein_id="HCR9915903.1"
                     /translation="MHITYDLPVAIEDILEAKKRLAGKIYKTGMPRSNYFSERCKGEI
                     FLKFENMQRTGSFKIRGAFNKLSSLTEAEKRKGVVACSTGNHAQGVSLSCAMLGIDGK
                     VVMPKGAPKSKVAATCDYSAEVVLHGDNFNDTIAKVSEIVETEGRIFIPPYDDPKVIA
                     GQGTIGLEIMEDLYDVDNVIVPIGGGGLIAGIAIAIKSINPTIKVIGVQAENVHGMAA
                     SYYAGEITAHRTTGTLADGCDVSRPGNLTYEIVRELVDDIVLVSEDEIRNSMIALIQR
                     NKVITEGAGALACAALLSGKLDSHIQNRKTVSIISGGNIDLSRVSQITGLVDA"
     gene            complement(7550..8488)
                     /gene="tdcA"
                     /locus_tag="OPV72_003718"
     CDS             complement(7550..8488)
                     /gene="tdcA"
                     /locus_tag="OPV72_003718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator TdcA"
                     /protein_id="HCR9915904.1"
                     /translation="MNTLVLPKTQHLVVFQEVIRSGSIGSAAKSLGLTQPAVSKIISD
                     VEAYFGVELIVRKNTGVTLTEAGQVLLSWSESITREMKNMINEMNSMTCNTVVDVSFG
                     FPSLIGFTFMSDMIHKFKEVFPKAQVSMYEAQLSSFLPALRDGRLDFAIGTLSNEMQL
                     QDLHVEPLFESEFVLVASKSRTCTGTITLESLKDEQWALPQTNMGYYSELLTTLQRNG
                     ISIENIVKTDSVVTIYNLVLNADFLTVIPCDMTTPFGSNQFITIPIKDTLPVARYAAV
                     WSKNYRIKKAASVLVELAKQYSSYNGCRRRQLIEIE"
BASE COUNT         2278 a         2412 c         2095 g         2118 t
ORIGIN      
        1 actttggtgc gcccttttct cagcttctgt cttctgcgtt atcccatagc ctgctcactc
       61 tgcgcctgtc gggcctatcc acaaacgact ttaatcgcca gaccgccgcg cgacgtctcg
      121 cgatatttgt cgttcatgtc tttacccgtt tcgtacatgg tttcgatcac tttatcgagc
      181 gaaacccgcg gctcagaggt acggcgtagc gccattcgcg ccgcatttac cgctttaacg
      241 gcgttaatcg cattacgttc aatacaaggg atttgcacct gacccgccac cgggtcacag
      301 gtgaggccaa ggttatgctc catcgcaatt tccgccgcaa tacagacctg cgccgggctg
      361 ccgcccagca gttctgtcag ccccgccgcc gccatcgaac acgcgacgcc aacctcgccc
      421 tgacacccca cttccgcgcc ggatatcgag gcgttcatct tgtacagcat gccaattgcc
      481 cccgccgaca gcagataacg ggcgatagag ttggcattga ccggacgacg gaatttgtcg
      541 taataggcca gcaccgcggg aataatgccg cacgcgccgt tggtcagcgc ggtgaccact
      601 cgcccgcccg ccgcgttctc ttcgctcacg gccagggcga acatgttaat ccagtcgatg
      661 acgttcatcg gatcgcggga gagattatcg ctggagacca gcagacgccg taacgctacc
      721 gcgcggcgtg ggacgttcag cggccccggc agcacgccct cagtattcat gccacgttca
      781 attccggtcg ccatcacctg ccaaatgcgg gcaaagccag cgtcaatctg ctctttgctc
      841 cgcaacgcca gttcattttg catcatcagg ccggaaaccg agagcccctg cctttcacac
      901 agcgtcagca gttcgctggc ggaatgaaaa tcatacggca ccgatttttc tacgtcgtgc
      961 gactgaccaa aacgttcctc ttcgacaata aagccgccgc caatagagta atacgttttg
     1021 tgtaaaagcg gcgtttgccc gtgccaggcg gtaattcgca taccgttttc atggcgcgcc
     1081 agggtttcag cgtgaaagag aatactgtcg gcgacgggaa aatccaccac atgcgcgcca
     1141 cccgccaccg ataaacggct gctgcgggca acctcctgga taaacgccgg aatgctatca
     1201 atattgacat cctgcggcgt attgcccgca agacccataa tgatggcggt atcggtcgcg
     1261 tggcctttgc ccgtcagcga tagcgatccg taaagatcaa ccgtgatgcg cgtcgttcgc
     1321 ggcaggtcgc cgctgtcgat cagccgatcg ataaaacatt ttcctgcatt cattggccct
     1381 acggtatggg agcttgaagg tccaatgcca atcttaaaaa tatcaaatgc gctaatcata
     1441 tctcccccta agattaccgt tcagtgaaga tccgtcgcgg ggcgatccac acgatcgccc
     1501 cgttcacgtt acatcgcctg agtaaaggtg cgcgaaataa cgtcctgttg ctgctcacga
     1561 gtcagcgcat tgaagcgcac ggcatagccg gaaacgcgga tcgtcaggtt cgggtagttt
     1621 tccggatgtt caatcgcatc cagcaacatt tcacggttca tgacattgac gttcagatgc
     1681 tgcccgcctt ctacctgtgc ttcatgatgg aaatagccgt ccagcaggcc gacaagattg
     1741 gttttccgca ccgcatcttc tttcccgagc gccgcaggca caatcgagaa ggtgtacgaa
     1801 ataccgtctt tggcgtaggt aaacggcagt ttcgccaccg acgtcagcga ggccaccgcc
     1861 cctttgcggt cacgaccgtg catcgggttc gcccccggcg cgaacggcgt tccggcgcgg
     1921 cgtccatccg gcgtattgcc ggtcttctgc ccgtacacga cgttcgaggt gatggtcaaa
     1981 atggactgcg tcggcaccgc attgcgatac gtcggcaaca cgctaatttt ttgcataaag
     2041 cgtttcacca ggtcgcaggc gatgctgtcc acgcgctcat cgttgttgcc gtactgcgga
     2101 tactcgcctt caatagcaaa gtcgatggca aggccatttt cgtcgcgaat cggcttcacc
     2161 tgagcgtacc tgatggcgga tagggaatcc gccgccaccg acagtccggc gatgccgcac
     2221 gccatcgtcc gatacacatc acggtcgtgc agcgccatca gcgaagcttc atagctgtac
     2281 ttatcgtgca tatagtgaat gatgttcagc gcgctaatgt actgcaccgc cagccagtcc
     2341 ataaaatggt cgaggctctc cattactgcg tcataatcca gcacctcatc cgttaacggc
     2401 gcggttttcg gcccaacctg gattttcagt ttctcgtcaa cgccgccatt gatagcgtac
     2461 agcaacgttt tggcaaggtt ggcgcgcgcg ccgaagaact gcatctgctt accgatgacc
     2521 atcgggctga cgcaacaagc gatggcgtaa tcgtcgctgt taaagtcggt acgcattaaa
     2581 tcgtcgtttt catactgcaa agatgaggtc acgatggaga cctgcgcagc atatttcttg
     2641 aatgccaccg gcaacgcttc tgaccacagt atggtcaggt tcggctccgg cgctggcccc
     2701 atcgtgtgca gggtatgcag ataacggaaa gagttcttcg tcaccagcgt gcggccatca
     2761 agccccatcc cgccaataac ttcggtggcc cagatcggat cgccggaaaa gagcgaatca
     2821 aattccggcg tgcgcaggaa gcgcaccatg cggatcttca tgatgaaatg gtcgatcagc
     2881 tcctgcgcct gctgctctgt cagaagaccc gcgttgaaat cgcgctcaat gtagatatca
     2941 aggaacgagg cggttcttcc cagcgacatt gcaccgccat tttgcgattt taccgccgcc
     3001 agataagcga agtagagcca ctgtaccgct tcctgcgcgt tccgcgccgg gcgggagata
     3061 tcatagccgt atttcgccgc catctcctgc atttgcagca gcgcgcgacg gtgctccgcc
     3121 aactcctcac gcaggcgaat cgtcgcctca agattctgtc cccgctccag attcgactgc
     3181 aggtcggcga attgcagctc gcgttcgcgc accagataac ggatgccata cagcgcgacg
     3241 cggcgataat cgccaataat gcgcccgcga ccataaccat ccggcaaacc ggttaatacg
     3301 ctggatttac ggcagcgcag catatccggc gagtaaacat cgaatacgcc ctgattatgg
     3361 gttttccgca ggtcggtaaa ggtatattca aaatcggcgt ccatttcccg gccataagcg
     3421 tggaatgaac ttttgatcat gttaacgccg ccaaacggat gcaaagcgcg tttaagcggc
     3481 ttatccgttt gtaaaccgac gattttttcc agctcttttt caatataccc cgcatcgtgc
     3541 gcggtaatcg tcgtcgcgat gttggtatcg aaatccaccg gcgcatgggt cgcgttctcg
     3601 atacgtattc ccgccatcac cttttcccac aacgctgtgg tcgctggcgt cgcgtcggcg
     3661 agaaaagatt catccccctc atagggcgta tagttatgct gaataaaatc acagacatta
     3721 atttcttctt tccagtccgt acctttaaaa tcacgccatg cttcggcata cagcatatcg
     3781 ctggtatcga tatttacctt catgaaaaat aatctctcta cagaacagcc gttaagttat
     3841 gcaaattcca ctggtgcttt cacgttgcct aaatgaatgg catcaagggc aatcattttc
     3901 tcttcattcg tgggaataac agcgcaaata acctgagaag ggttaacgga aataatgcgc
     3961 tcgccgtgag aattcggctg cttattcatt tcaacgtcta acgtaagccc cagtacgccc
     4021 aaatgttcaa tgaccaactg gcgaattaat actgaatttt caccaatacc gccggtaaaa
     4081 ataatgccat ccagccgatg taacgatgcc gcgtgtccgg caatgtgacg ggcgatacgg
     4141 tggacaaacg tttttatcgc taaccgggcg cgctcatgtc cttcgtgcca ggctttttcc
     4201 aggactctaa ggtcggatga caacccggag atgccgagca aaccggactc tttattcacc
     4261 actcgctcca gatcgctcaa cgtctgcccg gtttctttgg ctatccacgc catcgcgccg
     4321 aaatcaacgt cgccgctgcg agtgcccatc atcagcccct caagcggcgt catccccatt
     4381 gaggtgtcca cgctctgacc attgcgtacc gcgcagatag acgccccatt gcccagatgc
     4441 gcgacaatca gacccgagtt tttttcatcg aggtcaagca gttcatacgc gcgccgcgaa
     4501 acatagcgat gcgacgtacc gtgaaagccg tagcgacgca cacccaggct ggaaaaatat
     4561 tcccacggca atccgtataa ataggcttcc ggcgccagcg tctggtggaa actggtatca
     4621 aataccgcca cctgacgcac ggccgggaaa aggcgccgcg ccgcgtcaat gccgcttaaa
     4681 ttagcgtaat tatgcagcgg cgctaaaggt gatacccgac gaatattatc gataatctca
     4741 tcggtaataa tgacggactg cgtaaatagc tctccatcgt gcgcgatacg gtgaccaatt
     4801 aatgccacgc tatccgttaa atcacgtttt tccagctcaa aggcaatggc ttttaacgcg
     4861 tcctcataat tagagtgcga gaggtttatc ggcttatcgc cattaataga taaaaaggcg
     4921 ttttcagtat tcattccatc tgctattccc gccattaaaa catcacaggt agcgacatcc
     4981 agtacagaga atttgataga agatgatccg caattaatga ccagaacgac cggaaattca
     5041 ttcatgtagt gcctccgtcg atgtcagcct gcgtccacgc cctggggcgg aacgcaggct
     5101 aaacgtgagg attagaacaa tttgtagaca atattcagga tggtcagcag accaatcagg
     5161 gtgacgaaca cgttatccag acgaccacgg tacttcgcca gcgacggcgc tttacgaatg
     5221 gcgtacatcg gcagcaggca taacagtgag gcgataatcg gcgcgcccat cgcttcaatc
     5281 aggtccagaa tgttcgggtt tgcgtaagct acgacccagg tagatcccat aatgaagatc
     5341 atgctgatgg tattaagctt gcccatagag actttggttt tatcgccttt ataaccgaat
     5401 ttcagcacca ggccgttcag cccttccagc gtccccaggt agtggccgaa gaaagatttg
     5461 aaaatagcaa ccagcgcgat gatagacgcg ccatactcca gcaccgttgc aaaagtggat
     5521 tttgtccccg acaaagaggc gaaatggttg gccaggtagg aaagtaccgg aatgttctgc
     5581 gctttcgcat ccgccatgtt ctgcggggag agcgtaaaca gacagctaaa ggcgaagaac
     5641 atcaccacgg cgaccatcag catatggcgc gcgagatgat ctgtgaacat ttacgctcgg
     5701 taaattcgcg gccaaactct ttctcatact cttcacgctt agacaccacg aaggaagaga
     5761 cgatgggcga aaagttaaag gagaacacca taatagagat gcccagccac accgtaacca
     5821 gtatgccatc gtgcccggtc agcgcgatat tactgagatc aacctgatcg ataaccgccg
     5881 agttccagta aggaatcagc gataatgaga ttagcaccag actggcgata aacggccata
     5941 ccaggtaact catcacctta accatcagat ctttaccaaa ccagatcaca aaggccatca
     6001 gcagcagcaa gaacagcgcc acgaaaccgc gattcaacgc tggtatctgc aactggtttt
     6061 cccaaaacgt catgaacgtg ttagtaatgg tgacgccata aatccacagc agcggacaaa
     6121 tcgcaaagaa gtaaaggaac gtgataacta ccccgcccgt tttaccaaag tgctcttcga
     6181 ccgtttccgt aatattgccg gacggattag acccggataa acacagacgc gccagcgccc
     6241 ggtgacaata gaacgcaatg ggataagcta aaaccagcat cagcagaatg gggataagcc
     6301 cgccaaaccc ggcgcggata gggaagaaca gcaccccggc gccgatggcg gtaccaaata
     6361 aacccagcgt ccacgtcgtg tccgatttac gccatgacga ctgttttgcc tggctggata
     6421 caatgctatc agtagtactc atatcctatc ctcacgaaaa gattaagcgt caactaaacc
     6481 cgtaatttgt gatacacgag aaagatcgat attgccgcca gaaataatac tgaccgtttt
     6541 tctgttctga atatggctat ctaatttccc gcttaatagt gcggcgcagg ccagtgcgcc
     6601 agcgccttca gtaataacct tattgcgctg aattaaagcg atcatgctgt tacgaatttc
     6661 atcttcgcta accagaacaa tgtcatcgac taattcacga acaatttcat aggttaaatt
     6721 acccgggcgg gagacatcac aaccatccgc cagggtgccg gtcgttcggt gcgcggttat
     6781 ttcgccagcg taataagacg ccgccatacc gtgaacattt tcggcctgta cgccgataac
     6841 tttaatggtc gggttaatcg atttaatcgc aatggcaata cctgcaatta aaccgccgcc
     6901 gccaataggc acgatgacat tatcgacatc gtacagatct tccataattt ccagaccaat
     6961 agtaccctgc ccggcaatga cttttggatc gtcgtaaggc ggaataaaaa tgcggccttc
     7021 ggtttcgaca atttcactca ccttagcaat ggtgtcattg aagttgtcac cgtggagcac
     7081 cacttccgcc gaataatcac aggtggccgc cacttttgac tttggcgcgc ccttcggcat
     7141 cacgactttg ccgtcaatac ccagcattgc gcaagaaaga gaaacgccct gtgcatgatt
     7201 acctgtggaa caggccacga cgcctttacg tttttccgcc tccgttaacg agctaagttt
     7261 gttaaaagcg ccacgaattt taaatgaacc cgtacgctgc atattttcaa acttgagaaa
     7321 tatttcgcct ttgcaacgtt cactaaaata gttagagcga ggcattcccg ttttatatat
     7381 cttccccgcc agtctttttt tcgcttcgag gatatcttca attgcaaccg ggagatcgta
     7441 tgtaatgtgc attataacct cttaacctgg gtattaaaaa taagttaccg ttgcccactg
     7501 ttcaaaagaa acaggtggcg tcaatttcgc taaatatgtt tattccatat cattcaattt
     7561 ctattaactg cctgcgtctg catccattat atgatgaata ttgcttagcc aattctacta
     7621 atactgaagc ggcttttttg atacgataat ttttagacca taccgccgca taacgtgcga
     7681 cgggtaatgt gtctttgatt ggtatcgtga taaattgatt agagccaaaa ggcgtggtca
     7741 tatcgcaggg aataacagtt aagaaatcag cattgagaac aagattatat attgtgacaa
     7801 cggaatctgt tttaacaatg ttttcgatgc tgatgccatt tcgttgtaga gtggtgagta
     7861 attcgctgta gtagcccata ttcgtttgcg gcaacgccca ctgttcgtcc tttaacgatt
     7921 ccagtgtgat ggtgccggtg catgttcggg acttgctggc taccaggaca aactctgatt
     7981 caaacagcgg ctcgacatgc agatcctgta gctgcatttc attactgagc gtaccgatag
     8041 caaagtccag ccgcccgtcg cgcagggccg gcaggaatga agagagctgg gcttcgtaca
     8101 tggatacctg cgcttttgga aatacctctt tgaacttatg aatcatatcg gacatgaagg
     8161 taaagccaat cagcgaagga aaaccaaacg agacgtcgac aacggtattg cacgtcatac
     8221 tgttcatctc gttgatcatg tttttcattt cgcgggtgat agattcagac caggaaagca
     8281 gtacctgtcc cgcttcggtc aacgtaacgc cggtattttt gcgtacaatt agctcaacgc
     8341 caaaataggc ctcaacatcg ctaatgattt tactgacggc gggttgggtt aaccctaacg
     8401 attttgcggc agaaccgata gaaccacttc taatgacttc ctgaaagacc accaaatgct
     8461 gtgttttagg gagaacaaga gtattcatat ctaccgctct gaaataacat tgtgaacggc
     8521 aggaagtgta gcaaattaaa tcttaaaggt tatgtgcgac cactcacaaa ttaacttacc
     8581 gcaattttta catggtcttt attaaataaa gaaaacctat tacttcaatg agttacaaaa
     8641 acaagacagt aacttagcct gatttcaatc aaaaaaaatg gtcgggataa cgatatatta
     8701 tggcgataac cagcctattt tatctcctat tttcgacatt ccatgaagac gatatttcaa
     8761 tcaattacgg gacattttat cgacaattcc agcgttaaat ttaaaacgta atttctcaaa
     8821 tttaagtata aaccgaaggt aaatgcgctt aaaaaccgtt acgcgtcaca tttttttacc
     8881 ttatttgttt gtaaagaaac att
//
LOCUS       DAJVBX010000189         8875 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.189, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000189 DAJVBX010000000
VERSION     DAJVBX010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 8875)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8875)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8875
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.189"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(11..82)
                     /gene="ypdK"
                     /locus_tag="OPV72_003719"
     CDS             complement(11..82)
                     /gene="ypdK"
                     /locus_tag="OPV72_003719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_077777854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein YpdK"
                     /protein_id="HCR9915905.1"
                     /translation="MKYFFMGISFMVIVWAGTFALMI"
     gene            complement(485..1405)
                     /gene="lpxP"
                     /locus_tag="OPV72_003720"
     CDS             complement(485..1405)
                     /gene="lpxP"
                     /locus_tag="OPV72_003720"
                     /EC_number="2.3.1.242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kdo(2)-lipid IV(A) palmitoleoyltransferase"
                     /protein_id="HCR9915906.1"
                     /translation="MFPQSKFSRAFLHPRYWLTWFGVGVLWLLVQLPYPVLRFLGTRT
                     GKLARPFLKRRESIAQKNIELCFPTLSREEREKLIAENFHSLGMALLETGMAWFWPDS
                     RVRKWFDVDGLDNLTRAQAQNRGVMVVGVHFMSLELGGRVMGLCQPMMATYRPHNNPL
                     MEWVQTRGRMRSNKAMIGRNNLRGIVGALKKGEAVWFAPDQDYGPKGSSFAPFFAVEN
                     VATTNGTYVLSRLSGAAMLTVTMVRKSDNSGYRLYITPEMEGYPADENQAAAYMNKII
                     EKEIMRAPEQYLWIHRRFKTRPLGEASLYI"
     gene            1926..2168
                     /locus_tag="OPV72_003721"
     CDS             1926..2168
                     /locus_tag="OPV72_003721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfdY family protein"
                     /protein_id="HCR9915907.1"
                     /translation="MIYLWTFLAISILAVSGYIGQVMGAFSAVSSFTGMVILAALIYL
                     LNVWLQDGDDIVSGLLLFLAPACGLIIRFMVGYGKR"
     gene            complement(2407..3798)
                     /gene="pgtP"
                     /locus_tag="OPV72_003722"
     CDS             complement(2407..3798)
                     /gene="pgtP"
                     /locus_tag="OPV72_003722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate transporter PgtP"
                     /protein_id="HCR9915908.1"
                     /translation="MLTILKTGRSAHKVPPEKVQATYGRYRIQALLSVFLGYLAYYIV
                     RNNFTLSTPYLKEQLDLSATQIGLLSSCMLIAYGISKGVMSSLADKASPKVFMACGLV
                     LCVIVNVGLGFSSAFWIFAALVVFNGLFQGMGVGPSFITIANWFPRRERGRVGAFWNI
                     SHNVGGGIVAPIVGAAFAILGSEHWQSASYIVPACVAVIFALIVLVLGKGSPREEGLP
                     SLEQMMPEEKVILKTKNTAKAPENMSAWQIFCTYVLRNKNAWYISLVDVFVYMVRFGM
                     ISWLPIYLLTVKHFSKEQMSVAFLFFEWAAIPSTLLAGWLSDKLFKGRRMPLAMICMA
                     LIFVCLIGYWKSESLLMVTIFAAIVGCLIYVPQFLASVQTMEIVPSFAVGSAVGLRGF
                     MSYIFGASLGTSLFGVMVDKLGWYGGFYLLMGGIVCCILFCYLSHRGALELERQRQNA
                     LHNQDSLQLADAQ"
     gene            4234..5427
                     /gene="pgtC"
                     /locus_tag="OPV72_003723"
     CDS             4234..5427
                     /gene="pgtC"
                     /locus_tag="OPV72_003723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate transport regulator PgtC"
                     /protein_id="HCR9915909.1"
                     /translation="MFGSCQAYSRELVMATTFSPSATAWIIQRWQTEPGSVMIRTLNR
                     TSGSLEQLLDTANAENVDLILTSSPMLLQHLQEHQKLALLDSAPAASQKLVPRSIRST
                     SVAVAVSGFGLLINRSALAARHLPPPADWQDMGLPSYQGALLMSSPSRSDTNHLMVES
                     LLQQKGWTAGWATLLAISGNLVTISSRSFGVADKIKSGLGVAGPVIDNYANLLLNDPN
                     LAFTYFPYSAVSPTYVAVLKNSRHADEARAFIHYLLSPKGQRILADANTGKYPVAPLS
                     ADNPRAAQQQRLMAQPPLNYRLILKRQQLVQRMFDTAISFRLAQLKDAWRALHSAETR
                     LKRPLPEIRALLTSVPVDAASSEDETWLAQFDNKSFAEQKMMEWQIWFLNNQRLAIHK
                     LEELK"
     gene            5424..7430
                     /gene="pgtB"
                     /locus_tag="OPV72_003724"
     CDS             5424..7430
                     /gene="pgtB"
                     /locus_tag="OPV72_003724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     PgtB"
                     /protein_id="HCR9915910.1"
                     /translation="MKGRLLQRLRQLSISNSLRGAFLTGALLTLIVSMVSLYSWHEQS
                     SQVRYSLDEYFPRIHSAFLIEGNLNLAVDQLNEFLLAPNTTVRLQLRTQIIQHLDKIE
                     RLSQGLQLAERRQLAVILQDSRTLLAELDNALYNMFLVREKVSELSARIDWLHDDFTT
                     ELNSLVQDFTWQQGTLLDQIEANQGDAAQYLQRSREVQNEQQQVYTLARIENQIVDDL
                     RDRLNELKSGNNDGMLVETHIRYLENLKKTADENIRALDDWPSTITLRQTIDELLEIG
                     MVKNKMPDTMRDYVAAQKALLDASRAREATLGRFRTLLEAQLGSSHQQMQTFNQRLEQ
                     IVRVSGGLILVTTLLALLLAWGLNHYFIRSRLVKRFTALNQAVVQIGLGRTDSTIPVY
                     GRDELGRIARLLRHTLGQLNMQRRQLEQEVAERKEIEADLRAMQDELIQTAKLAVVGQ
                     TMTTLAHEINQPLNALSMYLFTAGRAIEQGQSGQARNTLTKAEGLINRIDAIIRSLRQ
                     FTRRAELETPLYPVDLRQTFVAAWELLAMRHQSRQGALSLPTDTVWVSGDEVRIQQVL
                     VNVLANALDACSHDAAIAVTWQTQGEALEVYIADNGPGWPGALLPSLLKPFTTSKAVG
                     LGIGLSISVSLMAQMKGDLRLASTLTRNACVVLQFSVTDVDDVE"
     gene            7420..8667
                     /gene="pgtA"
                     /locus_tag="OPV72_003725"
     CDS             7420..8667
                     /gene="pgtA"
                     /locus_tag="OPV72_003725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator PgtA"
                     /protein_id="HCR9915911.1"
                     /translation="MLNDECSILLIDDDVDVLDAYTQMLEQAGYRVRGFTHPFEAKEW
                     VKADWEGIVLSDVCMPGCSGIDLMTLFHQDDDQLPILLITGHGDVPMAVDAVKKGAWD
                     FLQKPVDPGKLLILIEDALRQRRSVIARRQYCQQTLQVDLIGRSEWMNQFRQRLQQLA
                     ETDIAVWFYGEHDTGRMTGARYLHQLGRNAKGPFVRYELTPENAGQLETFIDQAQGGT
                     LVLSYPEYLTREQQHHLARLQSLEHRPFRLVGVGSASLVEQAAANQIAAELYYCFAMT
                     QIACQSLSQRPDDIEPLFRHYLRKACLRLNHPVPEIAGELLKGIMRRAWPSNVRELAN
                     AAELFAVGVLPLAETVNPQLLLQEPTPLDRRVEEYERQIITEALNIHQGRINEVAEYL
                     QIPRKKLYLRMKKYGLSKEHYKF"
BASE COUNT         2244 a         2133 c         2304 g         2194 t
ORIGIN      
        1 cattgtactt ttaaatcatc agggcgaaag taccggccca aacgatgacc ataaatgaaa
       61 tgcccataaa gaaatatttc acgtttcatc tctccgcgta cctgtcgtac gcctaaatga
      121 acttacactt acctgattat agagagttga tgccggataa tacgaaattg agaattattc
      181 gtgtttcgac cgcctgcatc acctcagaat tctgcgcgtc atcgctccag acggcgctaa
      241 tgtacgccta aaaatgaggt gaaacaagag gcattttctt atttattttt agtaacttac
      301 aagtgtcgtg aatcggcgac agtttaattt ctgacagtga tgaatcgcta ttgagcgacg
      361 ccgccgacac agtaaaaaaa cgcctgtaaa caggagactt atcgctaaaa gcaggaatga
      421 gtaatttacg atgtgaatat tatggcaatg cgaaatgaca aaataaaagg ccttgcggcc
      481 tttttcagat gtagagtgac gcttccccca acgggcgagt cttgaaacgg cgatgaatcc
      541 agagatattg ctccggggcg cgcatgatct ctttctcaat aattttattc atataggcag
      601 cggcttgatt ttcatctgcc gggtaacctt ccatttcagg ggtaatatac agacgataac
      661 ccgagttatc ggatttcctt accattgtaa cggtcagcat ggcggcgcca gacagcctgg
      721 acagtacata ggtaccgttg gtggtggcga cgttttcaac cgcgaaaaat ggcgcaaagg
      781 agctgccttt aggaccgtag tcctggtcgg gagcaaacca aacggcttcc ccttttttta
      841 gcgcgcccac aatgccgcgc agattgtttc tgccgatcat cgctttattt gagcgcatac
      901 gaccgcgcgt ctgcacccac tccatgagcg gattgttatg cggacgatag gtcgccatca
      961 tcggctggca gagacccatt acccggcctc ccaattccag cgacataaaa tgcacgccaa
     1021 cgaccattac gccgcgattt tgcgcctgcg cacgggtaag gttgtccagc ccgtccacat
     1081 caaaccattt gcgaacccgg ctatcaggcc agaaccaggc catgcccgtt tcaagcagcg
     1141 ccatgccaag agagtggaaa ttctcggcga tcagtttttc cctttcttcc cgggagaggg
     1201 tcggaaaaca gagttcaatg tttttctgag cgatcgactc acgtcgcttc aggaaggggc
     1261 gcgccagctt accggtgcgg gtgcccagaa aacgcaaaac cgggtaggga agctgcacca
     1321 gtaaccagag gacgccaacg ccaaaccacg tcagccagta gcgcgggtgc aaaaacgcgc
     1381 gtgaaaattt gctttgagga aacataaaat accttctgta gatacgaaaa taatgtatcg
     1441 cagaagagtc attatccgca gcggtacact ctgaaatacg catcatcctt caagttgcgt
     1501 tcgcttatcc gaagcactta cttgagtaag ctcatcaggg taacttgaat gatttgcgta
     1561 tagttaggcc atcatgtacg acaatggttc ccgtaaggag tgtaaaacta agtcagtact
     1621 aaaccacgag ggcatgaacg ccaggcaggc taatgtacca ccagttattt actcgcgccc
     1681 agaaattctt tatcaagaag cgtaaatatt tctcccgtag caaaaataag ctaatcatta
     1741 tttttaatgc attgttttta cagtgataat tttatttcag acgaaggtta ttgaaaaatg
     1801 attagaaaat aaaatgtgag ataaatgtta tggaaatgac gtgctgataa ggtttatctt
     1861 aaaggagaag tgagagggac cgtaaggcta tatggaagcc ttgccataga caggaggtat
     1921 tatagatgat ctatttatgg acatttcttg caataagtat acttgccgtg agtggctata
     1981 tcggtcaggt gatgggggct ttttctgcgg tttcttcttt tacgggaatg gttatccttg
     2041 ccgcgctgat ttatttactc aatgtatggc tgcaggatgg cgatgacatc gttagcggat
     2101 tattgctttt tctcgcaccg gcatgtgggt taattattcg ctttatggtg ggatacggta
     2161 agcgttagtc agtacatacc tttcatactt caagtggctt atgtgttggc tatggattac
     2221 tcggcccatt catgggcctc gccctgacgg gacgtcgctc accccagtca catcgttatc
     2281 tatgctcccg gggactcact cccttgccgc ttttaagcaa ctcgaattat ttttggtata
     2341 cacgatgtca gcgaatagat agcgccgaca atgtcggcgc ttctgttccc cgggaaggct
     2401 aatcgtttat tgcgcgtccg caagctgcag tgagtcctga ttatgtaacg cattctggcg
     2461 ctggcgttcc agttccagcg cgccgcgatg ggagaggtaa cagaatagaa tgcagcacac
     2521 gatgccgccc atcagaagat aaaatccgcc gtaccagccc agtttatcca ccatgacgcc
     2581 aaacaggctg gtgcccaacg aggcgccgaa aatatagctc atgaacccac gtaaaccgac
     2641 ggcggaacct acggcaaagc tggggactat ctccattgtc tgtacggacg cgaggaattg
     2701 cgggacgtaa atcagacaac ctacaatggc ggcgaaaatc gttaccatca gcaaagattc
     2761 acttttccag tatccgatca gacagacaaa aatcagcgcc atgcaaatca tggctaacgg
     2821 cattctgcgg cccttaaaca gtttatctga cagccagcct gccagtagcg tagagggaat
     2881 tgccgcccac tcgaaaaaga gaaacgcgac gctcatctgt tcttttgaaa agtgttttac
     2941 tgtcaacaga tagataggca accagctaat catgccaaac cgcaccatat agacgaagac
     3001 atcgaccagc gaaatatacc aggcattttt attgcgcagc acataagtac agaagatttg
     3061 ccatgcgctc atattttccg gcgcttttgc cgtattcttc gttttcagta tgactttttc
     3121 ttccggcatc atctgttcca gggagggaag accttcttcg cgcggcgaac cttttcccaa
     3181 gaccagaaca attaaggcaa aaatgacggc gacgcaggcc ggaacgatat aactggcgct
     3241 ttgccagtgt tcgctgccca atatcgcaaa agccgcaccg acgataggcg cgacgatccc
     3301 gccgccaacg ttatgcgaga tattccagaa ggcgcctacg cgtccgcgtt cccgacgagg
     3361 gaaccagttt gcaatagtaa taaacgaggg gccgacgccc atgccctgaa aaaggccatt
     3421 gaagaccacc agagcggcaa atatccagaa tgcgctactg aatcccagcc caacgttaac
     3481 aatcacgcag agtaccagac cgcacgccat gaagactttt gggctggctt tatccgccag
     3541 actgctcatt acgcctttac tgattccgta agcaataagc atacagctac tcagcaggcc
     3601 gatttgcgta gcgctgagat ccaattgctc ttttaaataa ggcgtcgata atgtgaagtt
     3661 gtttctgact atatagtaag cgagatatcc cagaaatacg cttaacaatg cctgtatacg
     3721 atatcgacca tacgtagcct ggactttttc cggtgggact ttatgcgccg atcgccctgt
     3781 ttttaatatt gttaacatgg agtcacctgt attttatagt gagatgaaca tcaggaggtt
     3841 ttgtcggtag agtgaaagga gtgacaataa aattcaagtc gaggaaatgt gtcaaaattg
     3901 actcaattgg gtgaatttaa aggttatttt tgacccatcc tgaagggtgt ggtgaaactt
     3961 taattattgg catggccgtt ttatcgttag catgtgcgga tattaacaaa tttgctgcca
     4021 gtgatctgat acgctttatt gatgttttcg ggcgacggac ccgttattat tcaaataacg
     4081 ttgttctgga tgccaacaga aataaaaggg taagttttgt ctcaatattt tctttatgtg
     4141 atatcgatat ttatgaacgg gatcacaaat cgacttttct catactgtgg ttgtttcgcc
     4201 agagtgggcg cttttacgct atggctggcg gcgatgttcg gttcttgcca ggcgtacagc
     4261 cgcgagctgg tgatggcaac gaccttttca cccagcgcga ccgcctggat tatccagcgc
     4321 tggcagacgg agccgggttc cgtcatgatt cgtacgctca accgtaccag cggttcttta
     4381 gagcaattac ttgatacggc gaatgcggaa aatgtcgatc tgatcctgac gtcatccccc
     4441 atgctgttgc aacaccttca ggagcaccaa aagctggcgc tattggatag cgcgcctgcc
     4501 gccagccaga agctggtgcc gcgttctatc cgctcaactt cagtggcggt agcggtatcc
     4561 ggatttgggc tattgatcaa ccgttcagcg ctcgctgcgc gccatcttcc gccgcctgcc
     4621 gactggcagg atatgggcct gcccagttac cagggcgctc tattaatgag cagtccgtca
     4681 cgctcagaca ccaatcattt gatggtggag tcgctgttgc agcaaaaagg ctggacggca
     4741 gggtgggcga cgctgctggc aatctcgggt aatttggtca cgatttcctc tcgcagtttc
     4801 ggcgtagcgg ataaaatcaa aagcgggctt ggcgttgccg ggccggtcat tgataactat
     4861 gctaatttgc tactcaacga tcctaatctt gcttttacct attttccgta ttctgcggtg
     4921 tcgcccactt acgtcgcggt gttgaaaaac agccgtcatg cagacgaagc gcgtgctttt
     4981 attcattact tattaagtcc gaaagggcaa aggatactgg ctgacgcgaa taccggtaag
     5041 tatcccgtcg caccgcttag cgccgataat cctcgcgccg cgcaacaaca gcgtttgatg
     5101 gcccagccgc cgttgaacta tcgtctgatc ctgaagcgtc agcaactggt acaacgcatg
     5161 tttgataccg cgatcagttt tcgtcttgcg cagcttaaag atgcatggcg agcgttgcac
     5221 agcgcagaaa cgcggcttaa acgcccctta cctgaaatca gagccttatt gaccagcgtc
     5281 ccggtggatg cggcaagcag cgaagatgaa acctggctgg cgcagtttga taataaaagc
     5341 tttgccgaac aaaaaatgat ggagtggcag atctggtttc tgaacaatca gcggctggcg
     5401 attcacaaac tggaagagct gaaatgaagg ggagattatt gcaacggctt cgtcagctca
     5461 gtatcagcaa cagtttacgg ggtgcatttt taacgggcgc attactgacg ctgattgtca
     5521 gtatggtcag cctttattcc tggcatgagc aaagttcgca ggttcgctat tcgcttgatg
     5581 aatattttcc tcgcatccac tccgcttttt taattgaggg gaacctgaat ctggccgtgg
     5641 atcaactcaa tgaatttttg ctggcgccga acacgacggt acgtttgcag ttacgtacgc
     5701 agattattca gcatctggat aagattgagc gtctcagtca ggggcttcag cttgctgagc
     5761 gccggcaact ggccgtcatt ttacaggata gccggacctt gctggcggag ctggacaacg
     5821 ccctctacaa catgtttttg gtgcgggaga aagttagtga gctttccgct cgcatcgact
     5881 ggctccatga tgatttcacc acggagctaa attcgctggt acaggatttt acctggcagc
     5941 aagggacgct gctcgatcaa attgaggcga atcagggcga cgcggctcag tacttgcaac
     6001 gttcgcgcga ggtgcagaac gagcagcagc aggtatatac cctggcgcga attgaaaatc
     6061 agattgttga tgacctgcgc gacagattga atgagctcaa gtccggcaat aatgacggga
     6121 tgctggtgga gacccatatt cgctatctgg aaaacctaaa aaaaacggcg gatgagaata
     6181 ttcgtgcgct cgatgactgg cccagtacga tcacgctgcg gcaaaccatc gacgaactat
     6241 tggaaatcgg gatggtaaaa aataagatgc ccgataccat gcgcgattat gttgcggcgc
     6301 aaaaagcctt actggacgcc agccgcgcca gagaggctac gctagggcgc tttcgcacgc
     6361 tgcttgaggc gcagttaggt agtagtcacc agcaaatgca gacgttcaat caacgcctgg
     6421 aacagattgt tcgcgttagc ggcgggctta ttttagtgac gacgctcctg gcgttgctac
     6481 tggcctgggg actcaaccac tattttatcc gttcccgact ggtgaagcgt tttaccgcgc
     6541 ttaatcaggc tgtggtacag atagggctgg ggagaaccga ctcgactatc ccggtttacg
     6601 ggcgcgatga gctaggacgg atagcccgct tgctacgtca tacgctgggc cagctcaata
     6661 tgcaacgcag gcagcttgaa caagaggtcg ccgagcgcaa agagatagaa gccgacctgc
     6721 gcgccatgca ggatgagttg attcagacgg cgaaactggc ggtagtcggc cagaccatga
     6781 ccacgctggc gcatgaaatt aaccagccgc tgaatgcgct ttcaatgtat ttatttacgg
     6841 cgggacgcgc gattgaacaa ggtcagagcg gacaggcgag aaatacgctc accaaagcgg
     6901 aagggctcat taaccggatt gacgccatta tccgttcgct gcggcagttt acccgtcggg
     6961 cggagctgga aacgccattg tatcccgttg atctgcgcca aaccttcgtg gcggcatggg
     7021 agttattagc catgcgccac caatcccggc agggagcgct ttcactgcca accgacaccg
     7081 tatgggttag cggcgatgaa gtgcgtattc agcaggttct ggtgaatgtg ctggcgaatg
     7141 cgcttgacgc ctgttcgcat gatgcggcga tcgcggtgac atggcagacg cagggagagg
     7201 cgctggaggt ttatattgca gataacggcc ctggctggcc tggggcgctg ttgccctctt
     7261 tactcaagcc gtttaccacc agtaaagctg tcgggttggg tattgggctg tcgattagcg
     7321 tgtcgctgat ggcgcaaatg aagggcgacc tgcgtctggc gtcgacgctg acgcgtaatg
     7381 cttgcgtggt gctgcaattc tcggtaacgg atgtcgatga tgttgaatga tgaatgttct
     7441 attttgctga ttgatgatga cgttgatgta cttgacgcct atacccaaat gcttgagcag
     7501 gcaggctacc gcgtgcgtgg ctttacccat cctttcgagg ccaaagagtg ggtaaaagcg
     7561 gattgggagg ggatcgtttt gagcgatgtg tgtatgccgg ggtgttccgg tatcgatctt
     7621 atgacgctgt ttcatcagga tgacgatcaa ctgccaatct tattgattac cggacatggc
     7681 gatgtaccga tggcggttga tgcggtgaaa aagggcgcct gggattttct gcaaaaaccc
     7741 gtcgatccgg gcaaactgtt gatattaatt gaagacgcgc tacgccagcg ccggtcggtt
     7801 attgcacggc ggcaatattg ccagcagacg ttacaggttg acctgattgg gcgcagcgag
     7861 tggatgaatc agtttcgaca acggttacaa caactggcgg aaacggacat tgccgtatgg
     7921 ttttacggtg agcatgacac aggacgtatg actggcgccc gttatctcca tcagctgggg
     7981 cgtaacgcga aagggccgtt tgttcgctat gaactcacgc cggagaatgc cgggcagttg
     8041 gagacattca tcgaccaggc gcaaggaggc acgctggtgt tgagttatcc cgaatatctg
     8101 acacgcgaac agcagcacca tctggcgcgt ttacaaagcc tggagcatcg gccttttcgt
     8161 ttggtgggcg ttggcagcgc ttcgctggtg gagcaggcgg cagctaacca gatagcggcc
     8221 gagctttact actgtttcgc catgacccaa atcgcctgcc agtctctttc tcagcgaccg
     8281 gatgatatcg agccgttatt tcgccattat cttcgaaaag cctgcctgcg actcaatcat
     8341 ccagtgccgg aaatagcggg ggaattactg aaaggaataa tgcgacgcgc ctggccaagc
     8401 aatgtgcgcg aactggccaa tgcggcggag ctttttgctg tcggcgtgct gccgctggcg
     8461 gaaacggtca acccgcagtt gcttctgcag gagccgaccc cgcttgaccg gcgcgttgaa
     8521 gagtatgagc gacaaattat taccgaagca ttaaatattc atcagggacg aattaatgaa
     8581 gtggcggagt acttgcaaat tccccgtaaa aaactttatc tgcgcatgaa aaaatatggt
     8641 ctaagtaaag agcattataa attctgatat tacagttact ttcaatctgg ctgacaacaa
     8701 cagcaacgat gtcgttagcc agataacgtc gcattaccgt aatggtaaat cattccatta
     8761 tgattataga ttgcttatta ttcacctgag catcaaattc tatttcttaa cttcaatata
     8821 aggtaaaaat gcgtcaagtt ctctggcgta ataaatgtac tcttgtccga cgatt
//
LOCUS       DAJVBX010000190         8844 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.190, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000190 DAJVBX010000000
VERSION     DAJVBX010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 8844)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8844)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8844
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.190"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            54..296
                     /gene="ssaE"
                     /locus_tag="OPV72_003726"
     CDS             54..296
                     /gene="ssaE"
                     /locus_tag="OPV72_003726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YscE family type III secretion system
                     co-chaperone SsaE"
                     /protein_id="HCR9915912.1"
                     /translation="MTTLTRLEDLLLHSREEAKGIILQLRAARKQLEENNGRLQDPQQ
                     YQQNTLLLEAIEQAENIINIIYYRYHNSALVVSEQE"
     gene            499..825
                     /gene="sseA"
                     /locus_tag="OPV72_003727"
     CDS             499..825
                     /gene="sseA"
                     /locus_tag="OPV72_003727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system chaperone SseA"
                     /protein_id="HCR9915913.1"
                     /translation="MMIKKKAAFSEYRDLEQSYMQLNHCLKKFHQIRAKVSQQLAERA
                     ESPKKSRETESILHNLFPQGVAGVNQEAEKDLKKIVSLFKQLEVRLKQLNAQAPVEIP
                     SGKTKR"
     gene            832..1422
                     /gene="sseB"
                     /locus_tag="OPV72_003728"
     CDS             832..1422
                     /gene="sseB"
                     /locus_tag="OPV72_003728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system translocon
                     protein SseB"
                     /protein_id="HCR9915914.1"
                     /translation="MSSGNILWGSQNPIVFKNSFGVSNADTGSQDDLSQQNPFAEGYG
                     VLLILLMVIQAIANNKFIEVQKNAERARNTQEKSNEMDEVIAKAAKGDAKTKEEVPED
                     VIKYMRDNGILIDGMTIDDYMAKYGDHGKLDKGGLQAIKAALDNDANRNTDLMSQGQI
                     TIQKMSQELNAVLTQLTGLISKWGEISSMIAQKTYS"
     gene            1419..1892
                     /gene="sscA"
                     /locus_tag="OPV72_003729"
     CDS             1419..1892
                     /gene="sscA"
                     /locus_tag="OPV72_003729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SycD/LcrH family type III secretion system
                     chaperone SscA"
                     /protein_id="HCR9915915.1"
                     /translation="MKKDPTLQQAHDTMRFFRRGGSLRMLLDDDVTQPLNTVYRYAMQ
                     LMEVKEFAGAARLFQLLTIYDAWSFDYWFRLGECCQAQKHWGEAIYAYGRAAQIKIDA
                     PQAPWAAAECYLACDNVCYAIKALKAVVRICGEVSEHQILRLRAEKMLQQLSDRS"
     gene            1895..3349
                     /gene="sseC"
                     /locus_tag="OPV72_003730"
     CDS             1895..3349
                     /gene="sseC"
                     /locus_tag="OPV72_003730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system translocon
                     protein SseC"
                     /protein_id="HCR9915916.1"
                     /translation="MNRIHSNSDSAAGVTALTHHHLSNVSCVSSGSLGKRQHRVNSTF
                     GDGNAACLLSGKISLQEASNALKQLLDAVPGNHKRPSLPDFLQTNPAVLSMMMTSLIL
                     NVFGNNAQSLCQQLERATEVQNALRNKQVKEYQEQIQKAIEQEDKARKAGIFGAIFDW
                     ITGIFETVIGALKVVEGFLSGNPAEMASGVAYMAAGCAGMVKAGAETAMMCGADHDTC
                     QAIIDVTSKIQFGCEAVALALDVFQIGRAFMATRGLSGAAAKVLDSGFGEEMVERMVG
                     AGEAEIEALAEKFGEEVSESFSKQFEPLEREMVSPGEMEEESAEFSRNVEKNMTKNAG
                     KSFTKEGVKAMAKEAVKEALEKYAQEGEKFLLKNFRNKVLFNMFKKILYALLRDCSFK
                     GLQAIRCATEGANQMNTGMVNTEKAKLEKKIEQLITQQRFLDFIMQQTDDQKKIEQKR
                     LEGLYKGSGAALRGVLDTIDHYSSVQARIAGWRA"
     gene            3365..3952
                     /gene="sseD"
                     /locus_tag="OPV72_003731"
     CDS             3365..3952
                     /gene="sseD"
                     /locus_tag="OPV72_003731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system translocon
                     protein SseD"
                     /protein_id="HCR9915917.1"
                     /translation="MEASNVALVLPAPSLLTPSSTPSPSGEGMGTESMLLLFDDIWMK
                     LMELAKKLRDIMRSYNVEKQRLSWELQVNVLQTQMKTIDEAFRASMITAGGAMLSGVL
                     TIGLGAVGGETGLIAGQAVGHTAGGVMGLGSGVAQRQSDQDKAIADLQQNGAQSYNKS
                     LTDIMEKATEIMQQIIGVGSSLVTVLAEILRALTR"
     gene            3955..4371
                     /gene="sseE"
                     /locus_tag="OPV72_003732"
     CDS             3955..4371
                     /gene="sseE"
                     /locus_tag="OPV72_003732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LcrR family type III secretion system chaperone
                     SseE"
                     /protein_id="HCR9915918.1"
                     /translation="MVQEIEQWLRRHQVFTEPAYLGETAILLGQQFILSPYLVIYRIE
                     AKEMIICEFRRLTPGQPRPQQLFHLLGLLRGIFVHHPQLTCLKMLIITDVLDEKKAML
                     RRKLLRILTVMGATFTQLDGDNWTILSAEHLIQRRF"
     gene            4423..4857
                     /gene="sscB"
                     /locus_tag="OPV72_003733"
     CDS             4423..4857
                     /gene="sscB"
                     /locus_tag="OPV72_003733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SycD/LcrH family type III secretion system
                     chaperone SscB"
                     /protein_id="HCR9915919.1"
                     /translation="MMMKEDQKNKIPEDILKQLLSVDPETVYASGYASWQEGDYSRAV
                     IDFSWLVMAQPWSWRAHIALAGTWMMLKEYTTAINFYGHALMLDASHPEPVYQTGVCL
                     KMMGEPGLAREAFQTAIKMSYADASWSEIRQNAQKMVDTLIA"
     gene            4873..5655
                     /gene="sseF"
                     /locus_tag="OPV72_003734"
     CDS             4873..5655
                     /gene="sseF"
                     /locus_tag="OPV72_003734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion systems effector SseF"
                     /protein_id="HCR9915920.1"
                     /translation="MKIHIPSAASNIVDGNSPPSGIQAKEASFPPPEIPAPGTPTVPV
                     VLTPEQIRQQRDYAIHFMQYTIRALGATVVFGLSVAAAVISGGAGLPIAILAGAALVI
                     AIGDACCAYHNYQLICQQKAPLQTASDSVALVVSALALKCGASLNCANTLANCLSLLI
                     RSGIAISMLVLPLQFPLPAAENIAASLDMGSVITSVSLTAIGAVLDYCLARPSGDDQE
                     NSVDELHADPSVLLAEQMALLCQSATTPALMDSSGHTSRGEP"
     gene            5652..6341
                     /gene="sseG"
                     /locus_tag="OPV72_003735"
     CDS             5652..6341
                     /gene="sseG"
                     /locus_tag="OPV72_003735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460370.1"
                     /note="SseG, from Salmonella pathogenicity island 2, is a
                     type III secretion system (T3SS) effector protein; Derived
                     by automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pathogenicity island 2 effector protein SseG"
                     /protein_id="HCR9915921.1"
                     /translation="MKPVSPNAQVGGQRPVNAPEESPPCPSLPHPETNMESGRIGPQQ
                     GKERLLAGLAKRVIECFPKEIFSWQTVILGGQILCCSAGIALTVLSGGGAPLVALAGI
                     GLAIAIADVACLIYHHKHHLPMAHDSIGNAVFYIANCFANQRKSMAIAKAVSLGGRLA
                     LTATVVTHSYWSGSLGLQPHLLEHLNDLTYGLMSFTRFGMDGMAMTGMQVSSPLYRLL
                     AQVTPEQRAPE"
     gene            6435..6650
                     /gene="ssaG"
                     /locus_tag="OPV72_003736"
     CDS             6435..6650
                     /gene="ssaG"
                     /locus_tag="OPV72_003736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system needle filament
                     protein SsaG"
                     /protein_id="HCR9915922.1"
                     /translation="MDIAQLVDMLSHMAHQAGQAINDKMNGNDLLNPESMIKAQFALQ
                     QYSTFINYESSLIKMIKDMLSGIIAKI"
     gene            6628..6918
                     /locus_tag="OPV72_003737"
     CDS             6628..6918
                     /locus_tag="OPV72_003737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001531123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EscG/YscG/SsaH family type III secretion system
                     needle protein co-chaperone"
                     /protein_id="HCR9915923.1"
                     /translation="MESLLKSEVISDDVRRLLLEIMFAGVNHSLISQVHAMLPALTVI
                     VPDKKLQLVCLALLLAGLNEPLKAAKILSDIDLPEAMALRMLFPAPNEGFEN"
     gene            6930..7178
                     /gene="ssaI"
                     /locus_tag="OPV72_003738"
     CDS             6930..7178
                     /gene="ssaI"
                     /locus_tag="OPV72_003738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010989174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SctI family type III secretion system inner rod
                     subunit SsaI"
                     /protein_id="HCR9915924.1"
                     /translation="MSIVPVSTQSYVKSFAEPSQEQINFFKQLLKDEASTSNASALLP
                     QVMLTRQMDYMQLTVGVDYLARISGAASQALNKLDSMT"
     gene            7175..7924
                     /gene="ssaJ"
                     /locus_tag="OPV72_003739"
     CDS             7175..7924
                     /gene="ssaJ"
                     /locus_tag="OPV72_003739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system apparatus
                     lipoprotein SsaJ"
                     /protein_id="HCR9915925.1"
                     /translation="MKVHRIIFLTVLTFFLTACDVDLYRSLPEDEANQMLALLMQHHI
                     DAEKKQEEDGVTLRVEQSQFINAVELLRLNGYPHRQFTTADKMFPANQLVVSPQEEQQ
                     KINFLKEQRIEGMLSQMEGVINAKVTIALPTYDEGSNASPSSVAVFIKYSPQVNMEAF
                     RVKIKDLIEMSIPGLQYSKISILMQPAEFRMVPDVPARQTFWIMDVINANKGKVVKWL
                     MKYPYQLMLSLTGLLLGVGILIGYFCLRRRF"
     gene            7942..8490
                     /locus_tag="OPV72_003740"
     CDS             7942..8490
                     /locus_tag="OPV72_003740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HCR9915926.1"
                     /translation="MLQLYRYFWQPARYAVPEWLDKLGFHLSNCWRYGDRPKLDRLLD
                     RALNRLRGSSVIPACLNDRQKRQIRLAPRISAFAFGLGLFKLRCSDYFMLPEYRQLLL
                     QWFSEDEIWQLYGWLGQRDGKLLPPQVMQQTALQIGTAILNREAHDDAVLHALLVLLP
                     PPQRILWPKTSLTEIIFMEHLL"
     gene            8487..>8844
                     /gene="ssaK"
                     /locus_tag="OPV72_003741"
     CDS             8487..>8844
                     /gene="ssaK"
                     /locus_tag="OPV72_003741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system apparatus
                     protein SsaK"
                     /protein_id="HCR9915927.1"
                     /translation="MSFTSLPLTEINHKLPARNIIESQWITLQLTLFAQEQQAKRVSH
                     AIVSSAYRKAEKIIRDAYRYQREQKVEQQQEIAWLRKNTLEKMEVEWLEQHVKHLQED
                     ENQFRSLVDHAAHHIKN"
BASE COUNT         2543 a         1765 c         2217 g         2319 t
ORIGIN      
        1 taaacataat gatactttga ttaactatcc attagatttt aagtgagtgg aaaatgacaa
       61 ctctgacccg gttagaagat ttgctgcttc attcgcgtga agaggccaaa ggcataattt
      121 tacaattaag ggctgcccgg aaacagttag aagagaacaa cggtaggtta caggatccgc
      181 agcaatatca gcaaaacacc ttattgcttg aagcgatcga gcaggccgaa aatatcatca
      241 acattattta ttatcgttac cataacagcg cacttgtagt gagtgagcaa gagtaaagta
      301 aaaatatctt agagcctatc ccaccaggcg ttaattggcg cagccagttt ggacacggat
      361 agcgcgcaaa aaccggagcg tacacgtagt acgtgaggat tttgagcact gcccaggttc
      421 aaaatggcaa gtaaaatagc cctaatggga caggctctta gttagcacgt taattatcta
      481 tcgtgtatat ggaggggaat gatgataaag aaaaaggctg cgtttagtga atatcgtgat
      541 ttagagcaaa gttacatgca gctaaatcac tgtcttaaaa aatttcacca aatccgggct
      601 aaggtgagtc aacagcttgc tgaaagggca gagagcccca aaaagagcag agagacagag
      661 agtattcttc ataacctatt tccacaaggc gttgccgggg ttaaccagga ggccgagaag
      721 gatttaaaga aaatagtaag tttgtttaaa caacttgaag tacgactgaa acaacttaat
      781 gctcaagccc cggtggagat accgtcagga aaaacaaaaa ggtaaagcat aatgtcttca
      841 ggaaacatct tatggggaag tcaaaaccct attgtgttta aaaatagctt cggcgtcagc
      901 aacgctgata ccgggagcca ggatgactta tcccagcaaa atccgtttgc cgaagggtat
      961 ggtgttttgc ttattctcct tatggttatt caggctatcg caaataataa atttattgaa
     1021 gtccagaaga acgctgaacg tgccagaaat acccaggaaa agtcaaatga gatggatgag
     1081 gtgattgcta aagcagccaa aggggatgct aaaaccaaag aggaggtgcc tgaggatgta
     1141 attaaataca tgcgtgataa tggtattctc atcgatggta tgaccattga tgattatatg
     1201 gctaaatatg gcgatcatgg gaagctggat aaaggtggcc tacaggcgat caaagcggct
     1261 ttggataatg acgccaaccg gaataccgat cttatgagtc aagggcagat aacaattcaa
     1321 aaaatgtctc aggagcttaa cgctgtcctt acccaactga cggggcttat cagtaagtgg
     1381 ggggaaattt ccagtatgat agcgcagaaa acgtattcat gaaaaaagac ccgaccctac
     1441 aacaggcaca tgacacgatg cgatttttcc ggcgtggcgg ctcgctgcgt atgttgttgg
     1501 atgacgatgt tacacagccg cttaatactg tgtatcgcta tgccatgcag cttatggagg
     1561 taaaagaatt cgccggcgca gcgcgacttt ttcaattgct gacgatatat gatgcctggt
     1621 catttgacta ctggtttcgg ttaggggaat gctgccaggc tcaaaaacat tggggggaag
     1681 cgatatacgc ttatggacgc gcggcacaaa ttaagattga tgcgccgcag gcgccatggg
     1741 ccgcagcgga atgctatctc gcgtgtgata acgtctgtta tgcaataaaa gcgttaaaag
     1801 ccgtggtgcg tatttgcggc gaggtcagtg aacatcaaat cctccgacta cgtgcagaaa
     1861 agatgttaca gcagctttct gacaggagct aaaaatgaat cgaattcaca gtaatagcga
     1921 tagcgccgca ggagtaaccg ccttaacaca tcatcactta agcaatgtca gttgcgtttc
     1981 ctcgggttcg ctgggaaagc gccagcatcg tgtgaattct acttttggcg atggcaacgc
     2041 cgcgtgtctg ctatccggga aaattagtct tcaggaggca agcaatgcgt tgaagcaact
     2101 gcttgatgcc gtacccggaa atcataagcg tccatcattg cctgactttt tgcagaccaa
     2161 tcccgcggtt ttatcaatga tgatgacgtc attaatactc aacgtctttg gtaataacgc
     2221 tcaatcgtta tgccaacagc ttgagcgggc aactgaggtg caaaatgcat tacgtaataa
     2281 gcaggtaaag gagtatcagg agcagatcca gaaagcgata gagcaggagg ataaagcgcg
     2341 taaagcgggt atttttggcg ctatttttga ctggattacc ggcatatttg aaaccgtgat
     2401 tggcgcctta aaagttgtgg aaggttttct gtccggtaat cccgcagaaa tggctagcgg
     2461 cgtagcttat atggccgcag gttgtgcagg aatggttaaa gccggagccg aaacggcaat
     2521 gatgtgcggt gctgaccacg atacctgtca ggcgattatt gacgtgacaa gtaagattca
     2581 atttggttgt gaagccgtcg cgctggcact ggatgttttc cagattggcc gtgcttttat
     2641 ggcgacgaga ggtttatctg gcgcagctgc aaaagtgctt gactccggtt ttggcgagga
     2701 aatggttgag cgtatggttg gtgcagggga agcagaaata gaggcgttgg ctgaaaagtt
     2761 tggcgaagaa gtgagcgaaa gtttttccaa acaatttgag ccgcttgaac gtgaaatggt
     2821 ttcgccgggc gagatggaag aggagtctgc cgaattttct cgtaacgtag aaaaaaatat
     2881 gacaaaaaat gcgggaaaaa gttttacgaa agagggggtg aaagccatgg caaaagaagc
     2941 ggtaaaagaa gccctggaaa aatatgcgca agaaggggaa aagtttctgt taaaaaattt
     3001 tcgtaataaa gttctcttca atatgttcaa aaaaatcctg tatgccttac tgagggattg
     3061 ttcatttaaa ggcttacagg ctatcagatg tgcaaccgag ggtgccaatc agatgaatac
     3121 tggcatggtt aacacagaaa aagcgaagct tgaaaagaaa atagagcaat taataactca
     3181 gcaacggttt ctggatttca taatgcaaca aacggatgac caaaaaaaga tagaacaaaa
     3241 acgcttagag gggctttata aaggtagcgg tgccgcgctt agaggtgtat tagataccat
     3301 tgatcactat agtagcgttc aggcgagaat agctggctgg cgcgcttaat ctgaggataa
     3361 aaatatggaa gcgagtaacg tagcactggt attaccagcg ccttccttgt taacgccttc
     3421 ttccactcca tctccctccg gggagggaat gggtactgaa tcaatgcttc tgttatttga
     3481 tgatatctgg atgaagctaa tggagcttgc caaaaagctg cgcgatatca tgcgcagcta
     3541 taacgtagaa aaacaacgac tgtcctggga actgcaagtc aatgttttgc agacgcaaat
     3601 gaaaacaatt gatgaagcgt ttagagcatc aatgattact gcgggtggcg ccatgttgtc
     3661 gggagtgctg acgataggat taggggctgt aggcggggaa accggtctta tagcgggtca
     3721 agccgtagga cacaccgctg ggggagtcat gggcctgggg tccggtgtag cgcaacgtca
     3781 aagtgatcaa gataaagcga ttgccgacct gcaacaaaat ggggcacaat cttataataa
     3841 atccctgacg gacattatgg agaaagcaac tgaaattatg cagcaaatca tcggcgtggg
     3901 gtcgtcactg gttacggttc ttgctgaaat actccgggca ttaacgaggt aaatatggtg
     3961 caagaaatag agcaatggtt gcgtcggcat caggtgttta ctgagcctgc atatttaggg
     4021 gagaccgcca tattacttgg gcagcagttt atattatcgc cttacctggt gatctatcgt
     4081 attgaggcaa aagaaatgat tatttgtgag ttcaggcgcc tgacgcccgg gcaacctcga
     4141 ccacagcaat tgtttcactt actgggactt ttacgcggga tatttgtgca tcacccgcag
     4201 ttaacatgtt taaagatgtt gataatcacc gacgttctgg atgaaaaaaa agctatgcta
     4261 cgcaggaaat tattgcgcat cctgacagta atgggagcga cctttacaca gcttgatggc
     4321 gataactgga caattttatc cgccgagcat cttatccagc gacgttttta aatgaccttc
     4381 ctggcgtaaa tcattatcac gtgaaaataa caatcaatag gtatgatgat gaaagaagat
     4441 cagaaaaata aaatacccga agacattctg aaacagctat tatccgttga tccggaaacc
     4501 gtttatgcca gtggttacgc ctcatggcag gagggggatt attcgcgcgc cgtaatcgat
     4561 tttagctggc tggtgatggc ccagccatgg agttggcgtg cccatattgc attggctggc
     4621 acctggatga tgcttaaaga atacacgacg gccattaatt tctatggaca tgccttgatg
     4681 ctggatgcca gccatccaga accggtttac caaacgggcg tctgtctcaa aatgatgggg
     4741 gaacccgggt tggcgagaga ggcttttcaa accgcaatca agatgagcta tgcggatgcc
     4801 tcatggagtg agattcgcca gaatgcgcaa aaaatggttg atactcttat tgcttaaata
     4861 acagaacgaa atatgaaaat tcatattccg tcagcggcaa gcaatatagt cgatggtaat
     4921 agtcctcctt ccggtataca agcgaaggag gcatcgtttc ctccccctga aattccagcc
     4981 cctggcaccc ctacagttcc tgtggtgctt acgcctgaac aaataaggca gcagagggat
     5041 tatgctatac attttatgca atacacgatt cgtgcgctgg gggcgacagt cgtgtttgga
     5101 ttatcggttg ctgcagcggt aatttctggc ggagcaggat tacccattgc tattcttgcg
     5161 ggggcggcgc tcgtgattgc tattggggat gcttgctgtg cgtatcataa ttatcaattg
     5221 atatgtcagc aaaaggcgcc gttacaaacc gccagtgata gcgttgctct tgtggtcagt
     5281 gcgctggcct taaaatgcgg ggcaagtctt aactgcgcta acacccttgc taattgtctt
     5341 tctttattaa tacgttcagg aatcgctatt tctatgttgg ttttacccct acagtttcca
     5401 ctgcccgcgg ctgaaaatat agcggcctct ttggacatgg ggagtgtaat tacctccgtt
     5461 agcctgacgg cgataggtgc ggtactggat tattgccttg cccgcccctc tggcgacgat
     5521 caggaaaatt ctgttgatga acttcatgcc gatcccagtg tgttattggc ggaacaaatg
     5581 gcattgctct gtcaatctgc tactacacct gcattaatgg acagttctgg tcatacatct
     5641 cggggagaac catgaaacct gttagcccaa atgctcaggt cggagggcaa cgtcctgtta
     5701 acgcgcctga ggaatcacct ccatgtccct cattgccaca tccggaaacc aatatggaga
     5761 gtggtagaat tggacctcaa caaggaaaag agcggttatt ggccggactt gcgaaacgag
     5821 tgatagagtg ttttccaaaa gaaattttta gttggcaaac ggtcattttg ggcggacaga
     5881 ttttatgctg ttccgctgga atagcattaa cagtgctaag tggtggaggc gcaccgctcg
     5941 tagccctggc aggaattggc cttgctattg ccatcgcgga tgtcgcctgt cttatctacc
     6001 atcataaaca tcatttgcct atggctcacg acagtatagg caatgccgtt ttttatattg
     6061 ctaattgttt cgccaatcaa cgcaaaagta tggcgattgc taaagccgtc tccctgggcg
     6121 gtagattagc cttaaccgcg acggtagtga cgcattcata ctggagtggg agtttgggac
     6181 tacagcctca cttattagag catcttaatg atcttaccta cggactaatg agttttactc
     6241 gcttcggtat ggatgggatg gcaatgaccg gtatgcaggt cagcagccca ttatatcgtt
     6301 tgctggctca ggtgacgcca gaacaacgtg cgccggagta atcgttttca ggtatatacc
     6361 ggatgttcat tgctttctaa attttgctat gttgccagta tccttacgat gtatttattt
     6421 taaggaaaag cattatggat attgcacaat tagtggatat gctctcccac atggcgcacc
     6481 aggcaggcca ggccattaat gacaaaatga atggtaatga tttgctcaac ccagaatcga
     6541 tgattaaagc gcaatttgcc ttacagcagt attctacatt tattaattac gaaagttcac
     6601 tgatcaaaat gatcaaggat atgcttagtg gaatcattgc taaaatctga agttattagc
     6661 gacgatgttc gacggttgct gctggaaatc atgtttgcgg gcgttaacca tagcctgatt
     6721 tcccaggtac atgcgatgtt accagcgcta acggttattg ttccggataa aaaattacag
     6781 ttggtatgtt tggcattatt gttggcgggt ttaaatgagc cgttaaaggc cgcgaaaatt
     6841 ttatcggata ttgatttgcc agaggctatg gcgctacgaa tgttatttcc tgcaccaaat
     6901 gaggggtttg aaaattgaat atttctgata tgagcatagt gcctgtaagc actcaatctt
     6961 atgtaaagtc ctttgcagaa ccgagccagg agcaaattaa tttttttaaa caattgctga
     7021 aagatgaagc atccaccagt aacgccagtg ctttattacc gcaggttatg ttgaccagac
     7081 aaatggatta tatgcagtta acggtaggcg tcgattatct tgccagaata tcaggcgcag
     7141 catcgcaagc gcttaataag ctggatagca tgacatgaag gttcatcgta taatatttct
     7201 tactgtcctt acgttctttc ttacggcatg tgatgtggat ctttatcgct cattgccaga
     7261 agatgaggcg aatcaaatgc tggcattact tatgcagcat catatcgatg cggaaaaaaa
     7321 acaggaagag gacggtgtta ccttacgtgt cgagcagtcg cagtttatta atgcggttga
     7381 gctacttaga cttaacggtt atccgcatcg gcagtttaca acggcggata agatgtttcc
     7441 ggctaatcag ttagtggtat caccccagga agaacagcag aagattaatt ttttaaaaga
     7501 acaaagaatt gaaggaatgc tgagtcagat ggagggcgtg attaatgcaa aagtgaccat
     7561 tgcgctaccg acttatgatg agggaagtaa cgcttctccg agctcagttg ccgtatttat
     7621 aaaatattca cctcaggtca acatggaggc ctttcgggta aaaattaagg atttaataga
     7681 gatgtcaatc cctgggttgc aatacagtaa gattagtatc ttgatgcagc ctgctgaatt
     7741 cagaatggta cctgacgtac ccgcgagaca aacattctgg attatggacg ttatcaacgc
     7801 caataaaggg aaggtggtga agtggttgat gaaataccct tatcagttga tgttatcgtt
     7861 gacaggactg ttattaggag tgggcatcct gatcggctat ttttgcctga gacgccgttt
     7921 ttgagccgac ctgatcccga agtgttgcaa ctttatcgtt atttctggca acctgctcgt
     7981 tacgctgtac cggaatggct ggataagctg ggctttcatc tttcaaactg ctggcgttat
     8041 ggcgatcggc ccaaattgga tcgtcttctt gacagagcgt taaatagact aaggggaagc
     8101 tctgttattc cagcctgttt aaatgacagg caaaaacgac agattcgtct tgcgccgcgt
     8161 atatcggcat ttgcctttgg actgggatta ttcaaactca ggtgtagtga ctattttatg
     8221 ctaccagagt atcggcaatt gcttctacag tggtttagcg aggatgagat ctggcagcta
     8281 tatggttggt tggggcaaag agatggcaaa ttacttcctc cgcaagtgat gcaacaaact
     8341 gcattgcaga tcggtaccgc cattcttaat cgggaagcgc atgacgatgc ggttttacat
     8401 gcgctattag tattattacc ccctccgcag cgtatacttt ggccgaagac ttctcttacc
     8461 gagattatct tcatggagca tttgctatga gttttacttc acttcctctg acggaaatta
     8521 accataagct acccgctcga aatattattg agtcacagtg gataacatta caattaactt
     8581 tatttgcaca agagcaacaa gctaagagag tttcacatgc tattgtgagc tccgcttacc
     8641 gtaaggctga aaaaatcatc cgagacgcct atcgttatca gcgtgaacag aaagttgagc
     8701 agcaacaaga aatagcgtgg ttgcgtaaaa atacgctgga aaaaatggaa gtagaatggc
     8761 tggaacaaca tgtaaaacat ttacaagaag atgaaaatca atttcgttca ttggtcgatc
     8821 acgccgcgca tcatattaaa aata
//
LOCUS       DAJVBX010000191         8659 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.191, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000191 DAJVBX010000000
VERSION     DAJVBX010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 8659)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8659)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8659
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.191"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            30..617
                     /locus_tag="OPV72_003742"
                     /pseudo
     CDS             30..617
                     /locus_tag="OPV72_003742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017466162.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
     gene            701..3397
                     /locus_tag="OPV72_003743"
     CDS             701..3397
                     /locus_tag="OPV72_003743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017441527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HCR9915928.1"
                     /translation="MNNTWKSVLCPIACGVGMLLSASPYSASGKDIEFNTDFLDVKNR
                     DNVNIAQFSRKGFILPGVYLLQIKINGQTLPQEFPVNWVIPEHDPQGSEVCAEPELVT
                     QLGIKPELAEKLVWITHGERQCLAPDSLKGMDFQADLGHSTLLVNLPQAYMEYSDVDW
                     DPPARWDNGIPGIILDYNINNQLRHDQESGSEEQSISGNGTLGANLGAWRLRADWQAS
                     YDHRDDDESTSTLHDQSWSRYYAYRALPTLGAKLTLGESYLQSDVFDSFNYIGASVVS
                     DDQMLPPKLRGYAPEIVGIARSNAKVKVSWQGRVLYETQVPAGPFRIQDLNQSVSGTL
                     HVTVEEQNGQTQEFDVNTASVPFLTRPGMVRYKMALGRPQDWDHHPITGTFASAEASW
                     GVTNGWSLYGGAIGESNYQAVALGSGKDLGVVGAVAVDITHSIAHMPQDDGFDGETLQ
                     GNSYRISYSRDFDEIDSRLTFAGYRFSEKNFMSMSDYLDAKTYHHLNAGHEKERYTVT
                     YNQNFREQGMSAYFSYSRSTFWDSPDQSNYNLSLSWYFDLGSIKNLSASLNGYRSEYN
                     GDKDDGVYISLSVPWGNDSISYNGTFNGSQHRNQLGYSGHSQNGDNWQLHVGQDEQSA
                     QADGYYSHQGALTDIDLSADYEEGSYRSLSMSLRGGMTLTTQGGALHRGSLAGSTRLL
                     VDTDGIADVPVSGNGSPTSTNIFGKAVIADVGSYSRSLARIDLNKLPEKAEATKSVVQ
                     ITLTEGAIGYRHFDVVSGEKMMAVFRLADGDFPPFGAEVKNERQQQLGLVADDGNAWL
                     AGVKAGETLKVFWDGTAQCEASLPPTFTPELLANALLLPCKMLEGQPPTAPQKSSPLP
                     AQPLIQEHTQTDGQPAAPVATTTQTPPIPLADNHAVNRKDME"
     gene            3410..4183
                     /locus_tag="OPV72_003744"
     CDS             3410..4183
                     /locus_tag="OPV72_003744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001044456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HCR9915929.1"
                     /translation="MNKTNHFNRQALIATVLLAAPLVSHSAIVPDRTRVIFNGNENSI
                     TVTLKNGNATLPYLAQAWLEDDKFAKDTRYFTALPPLQRIEPKSDGQVKVQPLPAAAG
                     LPQDRESLFYFNVREIPPKSDKPNTLQLALQTRIKFFYRPVAVARQVDKTHPWQTKLT
                     LTYQGDGVIFDNPTPFYLVISNAGSKENETASGFKNLLIAPREKVTSPIKGASLGSSP
                     VVGYVDDYGGHRLLVFTCSGNTCKVNEEKTRDAEKKANK"
     gene            4203..4709
                     /locus_tag="OPV72_003745"
     CDS             4203..4709
                     /locus_tag="OPV72_003745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HCR9915930.1"
                     /translation="MTMLTRWKILVLLCGGFVTGTEAAGTKTVQLELHLVVTQPPPCT
                     VGGASVEFGDVLTTKVGDVSQTKPVGYSLNCDGRASDYLKLQIQGTTTTISGEQVLQT
                     SVQGLGIRIQQAGNKQLVPVGITDWLNFTLSGSNGPELEAVPVKEPTTQLAGGDFNAS
                     ATLVVDYQ"
     gene            4724..5194
                     /locus_tag="OPV72_003746"
     CDS             4724..5194
                     /locus_tag="OPV72_003746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006667202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HCR9915931.1"
                     /translation="MKRVLILTLLITRFACADNLTFHGKLINPPACTINNGETLEVSF
                     GSVIIDNIDGVNYLTEIPWTLTCDSSFRDDALTFTLSYLGTATPYSAKALTTNVPGLG
                     IELQQNGTVFPPGTSLTINESSLPTLKAVPVKQPGKEPAEGDFEAFATLQVDYQ"
     gene            5191..5727
                     /locus_tag="OPV72_003747"
     CDS             5191..5727
                     /locus_tag="OPV72_003747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HCR9915932.1"
                     /translation="MNRIFQTTGHLIGGVMLWAVCNTLPAATPNVHYSGKLVAGACNL
                     VVDNDTMATVDFHTIGSDNFDASGQTTPVPFTLSLQDCKTALANGVVVTFQGVEDSTL
                     PGLLALESSSIANGFAIGIETADQHPLIINASQGTEFMLAEGNTIINLQAWLQKTSGE
                     NIMPGEFNASAMVNFEYQ"
     gene            5786..6904
                     /locus_tag="OPV72_003748"
     CDS             5786..6904
                     /locus_tag="OPV72_003748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915933.1"
                     /translation="MEIKKSILVRKNIRLSGIIIDMLILTILLISTFDAVSDSSPVKA
                     SAINIALQGTPNTDYELNGDLRSNGGIMPKTLYMVCSGGKFSASQADCVAGQWVDIEV
                     VISADSHTFMNLTNMGNLSSSAFQEKRRARCTAKNSNTMDCIWESNFDINLFFSPSTN
                     ISSIERQSLTLHIEPTNNASPSLQQINISGDLIYQPSDYAVYNQGYTPDVLAYVNFYA
                     KYNIVQSSFGTQTGPATGALPGRLNLNGNVATTVSLYPEQLDASFSKTEFSITSASKE
                     FTGSGNNELLAEIYLNYGLQHCQPQTADSICGQILANANVSTSCGDHNITITTNMCNT
                     GNDQCDSDETWKIAEIFGTWGRVNVDTICAITVLLPYE"
     gene            7499..8329
                     /locus_tag="OPV72_003749"
     CDS             7499..8329
                     /locus_tag="OPV72_003749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016505598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915934.1"
                     /translation="MPDGLESTLEFDPSTSFINTTAVDNGITYSFTGEAVKATAHASC
                     TANQATNSAICVWDKSFSLPLTLLTKQNGITINQQNLTVSVIPGGGNNDTNQYSSLSG
                     HIIIDESVSSYTNYEPETSGIENLKLKWTVTVTEDTEGDVGIWNGSLVLNGSPASTLH
                     RYLLPEILDASFSENAIAHSTEVAMTGAKNNVELASVYLYHGNTPCDDTSLCNYSLNK
                     TSVSLVCHDLNAQLNFSNTCNASGTTHCLNGKVGTIKGTWERVNIDTTCAITVLIPYE
                     "
BASE COUNT         2396 a         2133 c         2102 g         2028 t
ORIGIN      
        1 cataaaacac gttaattaag gataacacga tgaagtcatc tcatttttgt aaactggcag
       61 taactgcatc tttagttatg ggaattgtct ccggcgctca agccgcgggt agcaacacag
      121 caaaggttac tttccttggt aatattgttg attccccctg ctctgtcaca ttggatacgg
      181 aagatcaaac agtcaatatg ggctcaagta tcggtaatgg cacgctgagt aatggtaaaa
      241 cgaccatcaa caatgcccgt acctttcata tcgatcttga gggttgtacc taggctaccg
      301 agaaaaatat gaatgtggta ttcactacag gtagtggaac cacagcggct acaggcgcca
      361 cggataatct cgcgctgatg aagactgacg gcactggcgc tattagcaac ataagcctgg
      421 caatcggcga tgcaggcaaa aacaatatca aactgggcga tacctataca caggccattg
      481 cggacctgga cagagatacc atccttgatg agaagcaaag cctgaatttc accgcctggc
      541 tggttggcgc agcaaccggc accgtaggca caggtgaatt cagcagcgcc gccaacgtca
      601 ctatctctta cctgtaattc agataacaga gtcacgacga taaataccct gccgctttag
      661 gtagggtatt cctgttgagt tttattgcgg aatatatttg atgaataaca catggaaaag
      721 tgttctttgc ccaatagcgt gtggagtggg aatgcttcta agcgcctccc cttatagcgc
      781 gtcaggcaaa gacatcgaat ttaataccga tttcctcgat gtaaaaaatc gcgataacgt
      841 caacattgca cagttttctc gtaagggttt tatcctgcca ggcgtctacc ttttacaaat
      901 taaaattaac ggacagactc tgccgcagga atttcctgtt aactgggtta ttccagaaca
      961 tgatccacaa ggaagtgagg tttgcgcaga accagaatta gttacgcaat tgggtataaa
     1021 gccggaactc gcggaaaaac tcgtctggat aacgcacggt gaacgacaat gtctggcgcc
     1081 agattcactg aaaggcatgg attttcaggc tgacctggga cactccacgc tgctggtgaa
     1141 tttaccccag gcgtatatgg aatacagcga tgtcgactgg gacccacccg cccgctggga
     1201 taatggtatt cccggcatca ttctggatta caacattaat aatcagctcc gccacgatca
     1261 agaaagcggc agcgaagagc aaagcatcag cggcaacggg acgttaggcg cgaacctggg
     1321 cgcatggcga ctacgggccg actggcaggc cagctacgac catcgtgacg atgacgagag
     1381 cacttccacc ctccacgatc agagctggag ccgctactac gcctatcgcg cactaccgac
     1441 gctcggggcc aaacttacgc tgggcgaaag ctatctccag tccgatgttt tcgacagctt
     1501 taactatatc ggtgccagcg tcgtttctga cgatcagatg ctgccgccga aactgcgcgg
     1561 ctatgcgccg gagatcgtgg gcattgcgcg ctctaatgca aaagtcaaag tctcctggca
     1621 ggggcgcgta ctgtatgaaa cgcaggtgcc cgcaggaccg ttccgtattc aggatctcaa
     1681 ccagtccgtt tccggtacgt tgcacgtcac cgtggaagag cagaacggtc agacccagga
     1741 gtttgacgtt aacaccgcat cggttccctt cctgacgcgc cccggcatgg tgcgctacaa
     1801 gatggcgctg ggccgcccgc aggactggga tcatcaccct attaccggca cattcgcctc
     1861 ggcggaggct tcgtgggggg tcaccaacgg ctggtcgctc tatggcggcg caattggaga
     1921 aagcaactat caggccgtgg cgctgggaag cggtaaggat cttggcgtgg tgggcgcggt
     1981 ggcggtggac attacgcact ccatcgccca catgccgcaa gacgacgggt ttgacggcga
     2041 aacgctgcag ggtaactcat atcgcatcag ctactcccgt gactttgatg aaatcgacag
     2101 ccgactaacc tttgccggat accgcttctc agaaaagaac tttatgagca tgagcgacta
     2161 tctggatgcg aaaacctatc atcatctcaa tgccggtcac gaaaaagaac gctatacggt
     2221 cacctataac cagaacttcc gtgaacaggg catgagcgcc tatttcagct actcacgcag
     2281 taccttctgg gacagcccgg atcagagtaa ctataacctg tctctttcct ggtacttcga
     2341 cttagggtcg ataaaaaatc tcagtgcgtc gctgaacggc tatcgcagcg aatataacgg
     2401 tgataaagat gatggcgtct atatctcgct gtctgttccc tggggcaatg attccatcag
     2461 ctacaacggt acgtttaacg gtagtcaaca ccgtaatcag ctcggctatt ccggccacag
     2521 ccagaacggc gataactggc agcttcacgt cgggcaggat gaacaaagcg cgcaggcaga
     2581 cggttattac agccatcagg gcgcgctgac ggacatcgat ctgagcgcgg attatgaaga
     2641 aggatcgtac cgttcgctga gtatgtcgct gcgcggcggc atgacgctga ccacccaggg
     2701 cggcgcgcta caccggggaa gtttagcggg cagcacacgt ttgctggttg ataccgacgg
     2761 cattgcggac gtccccgtta gcggtaacgg ctcgccaacc tcaaccaaca ttttcggcaa
     2821 ggccgtgatt gcggatgtcg gaagctattc gcgcagcctg gcgcgtatcg atctgaacaa
     2881 attgccggag aaggcggaag ctactaagtc ggttgtgcag atcacgctca ccgaaggcgc
     2941 catcggctac cgtcactttg acgtggtcag cggcgagaaa atgatggcgg ttttccggct
     3001 agcagacggc gacttcccac ctttcggcgc cgaagtgaaa aacgagcgcc agcagcagtt
     3061 gggcctggtg gccgatgacg gcaacgcctg gctggcgggc gtaaaagccg gggaaacatt
     3121 gaaagtcttc tgggatggca cggcgcagtg tgaagcatca ctcccgccca cgtttacacc
     3181 agagctattg gccaacgcgc tattgctgcc gtgcaaaatg ctggaaggtc agccccccac
     3241 cgcaccgcag aaaagttctc cgctgcctgc gcaaccgcta atccaggaac atacgcaaac
     3301 cgatggccaa ccggccgcgc cggtggcgac aaccactcaa accccgccca taccgctggc
     3361 tgacaaccat gcggtgaatc gcaaggatat ggaataaagg gaacctgtaa tgaacaagac
     3421 caaccatttt aatcgccagg cgcttattgc cacggtatta ctggctgcgc cgctggtgtc
     3481 acacagcgcg attgtgccgg atcgtacccg cgttattttt aacggcaatg aaaattcaat
     3541 caccgtcacg ctgaaaaacg gcaacgccac tctgccctat ctcgctcagg cgtggctgga
     3601 agacgataag ttcgccaaag atacccgcta ttttaccgcc ctgccgccgc tgcagcgtat
     3661 tgagccaaaa tccgacgggc aggttaaagt ccagccgtta ccagccgcgg ctggcctacc
     3721 gcaggaccgg gaaagtctgt tttatttcaa cgtgcgagaa attccgccga aaagcgataa
     3781 gcctaatacg ctccagctgg cgctgcaaac gcgtattaag tttttctacc gcccggtagc
     3841 cgtagcccgg caggtggata agacgcaccc gtggcagacg aagctcacgc tgacctacca
     3901 gggcgatggt gtgatcttcg acaaccccac accgttttac ctcgtcatca gcaatgccgg
     3961 tagcaaagag aacgagaccg cctccggctt taaaaacctg ctgattgccc cgcgtgaaaa
     4021 agtgacctct cccatcaaag gtgcctcgct cggcagctca ccggtggtgg gctacgtcga
     4081 tgattacggc ggccatcgcc tgctggtttt tacctgctca gggaatacct gcaaggtcaa
     4141 tgaggaaaaa acccgtgacg ctgagaagaa agcgaataag taatcctgtg cgaaagagat
     4201 ctatgacgat gttgactcgc tggaaaatac tggtgctgct gtgcggtgga ttcgttaccg
     4261 gcaccgaggc tgccggcaca aaaaccgtgc aactggagct gcatctggtc gtcactcaac
     4321 caccgccctg tacggtaggc ggcgcttccg tagagtttgg cgatgtcctg accaccaaag
     4381 ttggcgatgt ttctcaaacg aaacctgtgg gctacagcct gaactgcgat ggcagagcga
     4441 gtgactatct gaagctacaa attcagggga ccaccaccac catcagcggg gagcaggttc
     4501 tgcaaacttc ggtgcagggg ttaggcatcc gtattcagca ggcgggcaat aagcaactgg
     4561 ttccggttgg cataacggat tggctgaact tcaccctgag cggcagcaat gggccggagc
     4621 tggaagccgt accggttaaa gagcccacca cgcagttagc gggtggcgat tttaacgcca
     4681 gtgcgacgtt agtcgtggat taccagtgat ggagagattc atagtgaaaa gggtgcttat
     4741 cctgacgctt ttaatcaccc ggtttgcctg cgccgacaat ttgacctttc acggcaaact
     4801 gataaacccg cccgcctgta ctatcaataa tggtgaaacg ctggaggtca gttttggtag
     4861 cgtgattatt gataatattg acggcgtcaa ttacctgacc gagatcccgt ggacccttac
     4921 ctgcgacagc agctttcgcg atgacgcatt aacttttacg ttgagctatc tgggcacggc
     4981 gacgccttac tccgcaaaag ccttaaccac caatgtccct gggctgggca ttgaacttca
     5041 gcagaacggc acggtgtttc ctcccggcac gtcgctaacc atcaatgagt catcgcttcc
     5101 cacactaaaa gccgtgccgg taaaacagcc cggtaaagag cctgccgaag gcgattttga
     5161 agcttttgcc acgttacagg tggattacca atgaaccgta tttttcaaac taccgggcat
     5221 ttgatcggag gcgtaatgtt atgggcggtt tgcaatacgc tacctgctgc cacgcctaat
     5281 gtgcactaca gcggtaagct ggttgccgga gcctgtaacc tggtagtgga taatgacacg
     5341 atggcgacgg tggattttca tactattggc agtgacaatt tcgacgccag cgggcaaacg
     5401 actcctgttc cattcacact tagcctccag gattgcaaaa cagcgctagc caacggcgtg
     5461 gtggtgacct ttcagggtgt tgaagacagt accctgcccg gactgctggc gctcgaatcg
     5521 tcttctattg ctaacggttt tgctataggg attgagaccg cagatcagca cccgttaatt
     5581 atcaacgctt ctcaaggtac ggaatttatg ttggcagagg gaaataccat tatcaatctc
     5641 caggcatggc tacaaaaaac atcaggggaa aatattatgc ctggggaatt taacgccagc
     5701 gcaatggtta attttgaata ccaataatgt tatttaacaa aaaggcattg atgctctggc
     5761 cagaataaaa aggagttaca acgcaatgga aataaaaaaa agcatcttgg ttagaaaaaa
     5821 tatacgcttg tcaggaatca tcattgacat gctcatttta accatacttt taatcagcac
     5881 gtttgatgct gtatctgact cttccccggt aaaagcaagc gctatcaata ttgcacttca
     5941 aggaactccc aacacagatt atgaattaaa tggcgatctc cgctctaacg gagggataat
     6001 gccaaagacg ctttatatgg tatgttcagg aggaaaattc agtgcaagcc aggctgattg
     6061 cgttgccggt caatgggtag atatcgaagt tgtaatatct gcggacagtc atacgttcat
     6121 gaatttgaca aatatgggca atttgagttc ttctgcattt caggaaaaaa ggcgtgctcg
     6181 ctgtacagcg aaaaatagta atacgatgga ttgtatttgg gaaagtaact tcgacattaa
     6241 cttgtttttt tcaccttcta caaacatctc ctcaattgaa agacaatctc tgactctcca
     6301 tatcgagcct acgaataatg catcaccttc tctacagcaa atcaatatca gcggcgactt
     6361 aatctaccag ccttctgact acgcagtgta taatcaagga tatactcctg acgtcttagc
     6421 ctacgttaat ttttatgcta aatacaatat cgtccaatca agctttggta cacagacagg
     6481 cccggcgacg ggcgccctgc cgggacgcct caatctgaac gggaacgtag cgaccacagt
     6541 ttctttatat cctgaacaac ttgatgcctc tttttcgaaa acagaatttt ccatcacatc
     6601 tgccagcaaa gaatttacgg gttctggtaa taatgaacta ctggcagaaa tctatctaaa
     6661 ctatggacta cagcattgcc agccgcaaac ggcagatagt atttgtggtc aaatattagc
     6721 taacgcgaac gtttcaacat cgtgtggtga tcataatatt actatcacaa ccaatatgtg
     6781 caatacaggt aatgaccaat gtgatagtga tgaaacatgg aaaattgcag agatcttcgg
     6841 gacatggggc cgggttaatg tcgacactat atgcgctatt acagtattgc ttccctatga
     6901 ataatgctta gaaaaaatac tcggaaccct aaataatctc gcaaaacagt agattactta
     6961 tccgaaaaat ttttcggcct tcagtgaggg gctctgctcc agttgcgcga tcagatcatt
     7021 taaccaaaat aatagtcgaa caaaagaggc gagccatgaa cggctaccat ttctttcgcg
     7081 agttaagcga agaatgctga aaaaacagta cagaaaagtc aggataaaga gttatacaga
     7141 cggcttacca ctatcccaat gctgtataca ggattattgg ttagttcact ttactgctcc
     7201 taaaaaacct gcctcactta aaatttagca aaattattga ccaaggaaaa caaatgtgta
     7261 caaatttttt aaaaacatcg ctactaataa catccacttt ttggtgtatt gcgctacaat
     7321 gcgctgaagt aagaacggat ataaaatata attctcaaat tatttcacag tttgatagta
     7381 ttagcgcact ggctggcgat cctacattcg ataccatcca taccccatta ccaacaaaca
     7441 ttcatatcct ttcatcgtgc actaagtcag gtggaggggg ggttgtattc caggtacatt
     7501 gcctgatgga cttgaatcca ctcttgagtt tgatccatca acttctttca tcaatacaac
     7561 cgctgtcgat aacggtatca cttatagttt tactggtgaa gcggtaaaag cgacggcaca
     7621 tgccagctgt acggctaatc aggcaactaa cagcgcaatt tgtgtatggg ataaatcatt
     7681 ttcacttccc ctcaccttac ttaccaaaca gaacggaata accattaacc agcaaaatct
     7741 tacagtttcg gtaatacccg gaggaggaaa taatgatact aaccagtact catccctttc
     7801 cggccatatt attattgatg aatcggtaag cagctacacg aattatgaac cggaaacatc
     7861 gggcattgag aatttaaaat taaaatggac tgtaacagtg acagaagata ccgaaggtga
     7921 tgtcggtata tggaacggat cacttgtact taatggctct ccagcgtcca ccctacatcg
     7981 ttatttgctt ccagaaatat tagatgcttc attttctgaa aatgcgatag cgcacagtac
     8041 cgaagtcgcc atgactggcg caaaaaataa tgtcgagcta gcctctgtat atctctacca
     8101 tggcaatacg ccatgcgatg atacatcctt gtgtaactac agtcttaata agacatcagt
     8161 ttctcttgta tgtcacgatc tgaatgcgca acttaacttt agcaacactt gtaatgcttc
     8221 aggcacaaca cattgcctga acggaaaagt aggtacgata aagggtacct gggagagagt
     8281 caacatcgat acaacttgtg caattaccgt tttgataccc tacgaataaa cacaggaaaa
     8341 atgatgacca taagcaaaag aatcataatt tcatttattc tatttatgtg cttcaccaac
     8401 aatacatttg gatctggata cgttaagatc aatgccgaat tgaatgatat ggcaggcaga
     8461 ggggtaggca cagtgattta aatagtaatc tacggcgaag gggaaatctt tctttttggt
     8521 tgtacaggga acgcttcggc ataccagaaa ggaggtcagc ccctcacggg atagatgaaa
     8581 aaacagatcc agaatcgcag ggcgaaaaga gttaatgatg agaacagata aagaatgaag
     8641 aagcttagat ccagactca
//
LOCUS       DAJVBX010000192         8544 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.192, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000192 DAJVBX010000000
VERSION     DAJVBX010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 8544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8544
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.192"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            77..520
                     /locus_tag="OPV72_003750"
     CDS             77..520
                     /locus_tag="OPV72_003750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000209569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915935.1"
                     /translation="MTTLLQVIVLIFIVFFIFPGRKIFRRSKHLQDGRKLISSSSLML
                     RKFGSSRGYNADYYFDMQYLYEVADGITTAIPLTSIIEAKPGTTRVSGRSVWSVDWIT
                     AEGQRKQTRFLHNYTLFNRNFATFLKTVKQANPDACITSLTLFTL"
     gene            641..1483
                     /locus_tag="OPV72_003751"
     CDS             641..1483
                     /locus_tag="OPV72_003751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2030)-N(6))-methyltransferase
                     RlmJ"
                     /protein_id="HCR9915936.1"
                     /translation="MLSYRHSFHAGNHADVLKHTVQSLIIESLKEKEKPFLYLDTHAG
                     AGRYQLGSEHAERTGEYLEGIARIWQQDDLPAELEPYISVVKHFNRSGQLRYYPGSPL
                     IARQLLREQDSLQLTELHPSDFPLLRAEFQKDNRARVERADGYQQLKAKLPPVSRRGL
                     ILIDPPYEMKTDYQAVVSGISEGYKRFATGTYALWYPVVLRQQIKRMIHELEATGIRK
                     ILQIELAIRPDSDQRGMTASGMIVVNPPWKLEQQMNNVLPWLHSRLAPNGHGHTSVSW
                     IVPE"
     gene            1588..2940
                     /gene="gorA"
                     /locus_tag="OPV72_003752"
     CDS             1588..2940
                     /gene="gorA"
                     /locus_tag="OPV72_003752"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003861215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HCR9915937.1"
                     /translation="MTKHYDYIAIGGGSGGIASINRAAMYGQKCALIEAKELGGTCVN
                     VGCVPKKVMWHAAQIREAIHLYGPDYGFDTTINQFDWSKLIASRTAYIDRIHTSYDNV
                     LGKNNVDVIKGFARFVDAKTIEVNGETITADHILIATGGRPSHPSIPGVEYGIDSDGF
                     FALSALPERVAVVGAGYIAVELAGVINALGAKTHLFVRKHAPLRSFDPMISETLVEVM
                     NAEGPQLHTHAVPKAVVKNADGSLTLELEDGRSETVDCLIWAIGREPSTDNINLAAAG
                     VKTNEKGYIIVDKWQNTNVEGIYAVGDNTGAIELTPVAVAAGRRLSERLFNNKPDEHL
                     DYSNIPTVVFSHPPIGTVGLSEPQAREQYGDEQVKVYKSSFTAMYTAVTTHRQPCRMK
                     LVCVGPEEKIVGIHGIGFGMDEMLQGFAVALKMGATKKDFDNTVAIHPTASEEFVTMR
                     "
     gene            complement(2987..3317)
                     /locus_tag="OPV72_003753"
                     /pseudo
     CDS             complement(2987..3317)
                     /locus_tag="OPV72_003753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462499.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
     gene            complement(3250..4104)
                     /locus_tag="OPV72_003754"
     CDS             complement(3250..4104)
                     /locus_tag="OPV72_003754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010989272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCR9915938.1"
                     /translation="MMGMKETVSNIVTSQAEKGGVKHVYYVACGGFYAAFYPAKAFLE
                     KEAKALTVGLYNSGEFINNPPVALGENAVVVVASHKGNTPETIKAAEIARQHGAPVIG
                     LTWIMDSPLVAHCDYVETYTFGDGKDIAGEKTMKGLLSAVELLQQTEGYAHYDDFQDG
                     VSKINRIVWRACEQVAERAQAFAQEYKDDKVIYTVASGAGYGAAYLQSICIFMEMQWI
                     HSACIHSGEFFHGPFEITDANTPFFFQFSEGNTRAVDERALNFLKKYGQRYYPETFTE
                     GECVIGAG"
     gene            complement(4280..4999)
                     /locus_tag="OPV72_003755"
     CDS             complement(4280..4999)
                     /locus_tag="OPV72_003755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCR9915939.1"
                     /translation="MIEQPDSKSAKPLYKQLEDALKEAIARGEYKPGQQIPTENELSV
                     RWQVSRVTVRKALDALTRENLLTRVSGKGTFVSGEKFQRSMTGIMSFSELCQSQGRRP
                     GSRTIKSVFESVDDETKALLNMNDGEKAVVIERIRYADDVAVSLETVHLPPRFAFLLD
                     EDLNNHSLYECLREKYHLWFTHSRKMIELVYASFEVAHYLGVNEGYPLILIKSEMIDN
                     KGELSCVSQQLIVGDKIRFTV"
     gene            5324..6973
                     /locus_tag="OPV72_003756"
     CDS             5324..6973
                     /locus_tag="OPV72_003756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-trehalase"
                     /protein_id="HCR9915940.1"
                     /translation="MLNQKLNPTPSEDLTIDVDLFYETDPCELKLDEMIEAEPEPEMI
                     EGLPASDALTPADRYLELFEHVQSTKLFPDSKTFPDCAPKMDPLDILIRYRKVRRHRD
                     FDLRRFVENHFWLPETLSSEYVSNPENSLKEHIDQLWPILTREPQDHIPWSSLLALPQ
                     SYIVPGGRFSETYYWDSYFTMLGLAESGREDLLKCMADNFAWMIENYGHIPNGNRTYY
                     LSRSQPPVFALMVELFEEDGVRGARRYLDHLKMEYAFWMDGAESLALNQAYRHVVRMP
                     DGSLLNRYWDDRDTPRDESWLEDVETAKHSGRPPNEVYRDLRAGAASGWDYSSRWLRD
                     AGRLASIRTTQFIPIDLNAFLYKLESAIANISALKGERDTEALFRQKASDRRAAVNHY
                     LWDDENGCYRDYDWRREEMALFSAASIVPLYVGMANHEQADRLANVVRSRLLTPGGIM
                     ATEYETGEQWDKPNGWAPLQWMAIQGFKRYGDDMLGDEIAHNWLKTVNHFYQEHHKLI
                     EKYHISGGTPREGGGGEYPLQDGFGWTNGVVRRLIGLYGEP"
     gene            complement(6986..>8544)
                     /locus_tag="OPV72_003757"
     CDS             complement(6986..>8544)
                     /locus_tag="OPV72_003757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915941.1"
                     /translation="PFEHSLGIIRQASIEILLLLGIHTTEGKEPRWFMEQLEQARLNL
                     GGWGAVAKKLRINDAQLSQFMLQLRHLQQHVPQYDSGQEVSENQLLAALRFVTSLEHL
                     RQQQPLLTYQTELEDPDQEAHLEAQRQLRAIELTLKALIARAWPDRASLNHYLKQHFG
                     PDRLRQWLKQGEDQHALEGMLFSELALMVVDKKLFARHYVRIFNDASALTLFAESRTT
                     LRMFLDDCRLARNEVIARQPLTSAQLMLLNVQYQQIVRPIQRAYAEKRTRVNPASFLL
                     ADERELRQFWETARLKDRQAGGDKHEISESIEPPRKRPPRTPEEREQLISGALWGGVG
                     VMTLAILAGAFWLFSSSSPSSDNGQAPAMAQDEPPREAPSARETLNHMGITWDAFTMR
                     AAIERNDTRVTALFLQGGMNWQLAWTEQAFAAGHTEVLQLLLRYPALMDEVKPCRRFI
                     TTLSHDMSSGAPLTAMHKTYLQTFCTVPAVVTRQQYDTEQAQLRAQARPSADNKKWLK
                     IQSAIYDAIH"
BASE COUNT         2010 a         2319 c         2196 g         2019 t
ORIGIN      
        1 atcgctgtca tttttgcgca aactgcccat gtataatatt ctcaactttt tcgtttctgg
       61 aatacaagga ttgtatatga ccacgttatt acaggttatt gtactgatat ttattgtttt
      121 ctttattttc cctgggcgaa aaattttccg tcggagtaag catctgcaag atggccgtaa
      181 attaatttca tcttcttcgc tgatgctgcg aaaatttggc agttctcgcg gctataacgc
      241 ggattactac tttgacatgc agtacctcta tgaggtcgcg gacggtatca ccaccgcgat
      301 accactcacc agcattattg aggcgaaacc gggaacaacg agagtcagtg gtcgttcagt
      361 ctggtcagtc gactggataa cagcggaagg gcaaagaaaa cagacgcgct tccttcataa
      421 ctacacccta ttcaatcgaa attttgccac cttccttaag accgtgaaac aggccaatcc
      481 agacgcctgc atcacttcgt tgacgttatt tacgctctga cgccacagcc tacttgtttt
      541 tcctcctggc caacggcgat aaaagcgcaa gagcggtaat ctctacggat ctgcggtaaa
      601 ctatcggcta acttgtttac ttcccggaat atctgcatcc atgctcagtt atcgtcacag
      661 ctttcacgct ggcaaccacg ccgacgtcct taaacatacc gttcagagcc tgatcatcga
      721 gtcgctaaaa gagaaagaaa aaccgtttct ctatctggac acgcacgcgg gcgcggggcg
      781 ttatcagttg ggcagcgaac atgctgaacg taccggagag tatctggaag gcatcgcccg
      841 tatctggcag caggacgatc tgcccgccga actggaaccg tatattagcg tcgtaaaaca
      901 tttcaaccgc agcgggcagt tacgctacta tccgggctcc ccgttaatcg cccgccagtt
      961 gctgcgtgag caggacagtc tgcaactcac ggaattgcat cccagcgact tcccactgtt
     1021 gcgcgcggag tttcaaaaag acaaccgcgc ccgcgtggaa cgcgctgacg gctatcagca
     1081 actgaaagcc aaattgccgc cggtttcccg ccgcggtctg attctcattg acccgcctta
     1141 tgaaatgaaa accgattacc aggcggtagt cagcggcatc agcgagggtt ataaacgttt
     1201 cgccaccggt acatacgcgc tatggtatcc ggtggtactc cgccagcaaa ttaagcgcat
     1261 gattcatgag ctggaggcca ccggcatccg taaaatcctg caaattgagc tggcgatccg
     1321 cccggacagc gatcagcgcg ggatgacggc gtccggtatg atcgtggtta acccgccgtg
     1381 gaaactggag cagcagatga acaacgtgct accgtggctg cacagcaggt tggcgccaaa
     1441 cggtcacgga cacacttcgg taagctggat cgtgccggag taatcacagc catcggtgga
     1501 acctttcacc ttcaggtata caatcgcgaa tattttggcg ggtagcgcag aatctatccg
     1561 tccgacaacg aacataaagg agcggtcatg accaaacact atgattacat cgctatcggc
     1621 ggcggcagcg gcggtatcgc ctcgattaac cgcgccgcta tgtacggcca gaaatgcgcg
     1681 ctcatcgaag ccaaagagct gggcggcacc tgtgttaacg tgggctgcgt gccgaagaaa
     1741 gtgatgtggc atgccgcgca gattcgtgaa gcgattcatc tgtatggccc ggactacggt
     1801 tttgacacca cgattaatca gttcgactgg agcaagctga ttgccagccg taccgcgtat
     1861 attgaccgca tccatacttc atacgacaac gtgctgggca aaaataacgt agatgtgatt
     1921 aaaggctttg cccgctttgt cgatgccaaa accattgaag tgaacggcga aaccatcacc
     1981 gctgaccata ttttgatcgc taccggcggc cgtccgagcc atccgagcat tccaggcgtg
     2041 gaatacggca ttgattccga cggtttcttt gcgctatctg ccttgccgga gcgcgtcgcg
     2101 gtggtaggcg caggttatat cgccgttgaa ctggctggcg ttatcaacgc gctgggggcg
     2161 aaaacgcatc tgtttgtccg taaacatgcg ccgctgcgca gttttgaccc gatgattagc
     2221 gaaacgctgg ttgaggtgat gaacgccgaa ggcccgcaac tgcatactca cgccgtgccg
     2281 aaagcggtgg tgaaaaacgc cgacggcagt ctgactctgg aactggaaga tggccgcagt
     2341 gaaaccgttg attgcctgat ctgggccatt ggtcgcgaac cgtcgaccga caatattaat
     2401 ctggcggcag cgggcgtgaa aaccaatgaa aaaggttaca tcatcgttga taaatggcag
     2461 aacacgaacg tagaaggcat ttacgccgtt ggcgacaata ctggcgcgat agaactaacg
     2521 ccagtcgccg tcgccgccgg tcgccgtctc tccgagcgcc tgtttaacaa caagccggac
     2581 gagcatctgg actacagcaa catcccgacc gtggtcttta gccatccgcc tatcggcact
     2641 gtcgggttaa gcgagccgca ggcgcgcgag cagtacggcg acgagcaggt gaaagtctat
     2701 aaatcatcgt ttaccgctat gtataccgcg gtgacgacgc accgccagcc gtgccgtatg
     2761 aagctggtct gcgtcgggcc ggaagaaaaa attgtgggta tccacggtat cggcttcggc
     2821 atggatgaaa tgttgcaggg cttcgcagtg gcgctgaaga tgggcgctac caagaaagac
     2881 ttcgataata ccgtcgctat tcacccgacc gcatcggaag agtttgtgac catgcgttaa
     2941 tatcttgtgc gcccatcttc gagggtgggc gcacaggcct tcatgattaa tacgtactga
     3001 aataactctg gatcagttcc ggattacgcg tctgagttaa tgccatcatc agtaacaccc
     3061 gcgccttcgc cgggttgagc gagtcagaca ccagccctgg ctgtccttgc gccatcggcg
     3121 ctgattgccg acgcgggccg cattgcagcg gtaaacacca ccggtttgtc gcttttcacg
     3181 gtcaaattaa gaaagtaggc ggtttcatcg agcgtgtcag tgccatgagt aatgaccaca
     3241 ccgtcaacat catcccgcgc caataacgca ttcaccttct gtgaaagttt caggataata
     3301 tcgctggcca tattttttca ggaagtttaa cgcgcgttca tccaccgccc gcgtattgcc
     3361 ctcggaaaac tggaagaaga aaggcgtatt cgcatcggta atttcaaagg gcccgtggaa
     3421 aaactcaccg ctatgaatac aggcggaatg tatccattgc atttccataa agatacagat
     3481 gctctgtagg taggctgcgc catagcccgc gccgctggcg acggtgtaaa tgactttatc
     3541 gtctttatat tcctgcgcga acgcctgcgc acgctccgct acctgctcgc aagcacgcca
     3601 gacgatacgg ttgattttgc tgacgccatc ctgaaaatcg tcgtagtgcg catacccttc
     3661 cgtctgctgg agcagttcga ccgcactcag caggcctttc atcgttttct ctccggcaat
     3721 atctttaccg tcgccaaacg tgtacgtttc cacatagtcg caatgcgcca ccaacggtga
     3781 atccattatc caggttaaac caatgaccgg cgcgccgtgc tgacgggcga tttcagccgc
     3841 tttaattgtc tctggcgtat tacctttgtg ggaggcgaca accacaacgg cattttctcc
     3901 cagcgctacc ggcgggttgt taataaattc tccgctgtta tacagaccga cagtcaacgc
     3961 tttcgcttct ttttctaaaa atgctttcgc cggatagaac gccgcataaa aaccgccgca
     4021 cgccacgtaa tagacgtgtt taacgcctcc tttctctgcc tggctggtca caatattgct
     4081 aactgtctct ttcataccca tcatgctttc ctctggttcc atcaatgata caggcgagga
     4141 ttcgccataa atgactcata atgtattatt atttttatat gatatttaaa gacatttgat
     4201 caagatggaa accaaaaaaa atcgggatcc gcgatctgga tcccgattca gcctgctctt
     4261 cgttagcgta atgctgacat catacggtaa accgtatttt atcgccgaca atcaactgtt
     4321 gcgaaacgca ggagagttct cctttgttat caatcatttc actttttatc aggatcagcg
     4381 gataaccctc gttaacgcca agataatggg cgacttcaaa gctggcataa accagttcga
     4441 tcatcttacg ggagtgggta aaccataaat ggtatttctc gcgtaagcat tcatacaaag
     4501 agtgattatt aagatcttcg tccagcaaaa acgcaaaacg tgggggaaga tgtacggttt
     4561 ccagcgatac cgccacatcg tcggcatagc ggatacgttc aatgacgacc gctttttcgc
     4621 catcgttcat attcagtaac gcttttgtct catcgtctac cgattcaaaa acggatttga
     4681 tggtgcgtga ccccgggcga cgtccctggg actggcataa ctcgctgaaa ctcatgatgc
     4741 cggtcatgct acgctgaaat ttctcaccag aaacaaaggt gcctttgccg gagacacggg
     4801 tcagcaaatt ttcacgcgtc agcgcatcca gcgccttacg gaccgtgacc ctgctcacct
     4861 gccagcgcac gctcagttca ttttccgtcg ggatctgctg gcctggttta tactctccac
     4921 gcgcaatagc ctcttttaag gcgtcttcaa gctgcttata aagcggtttg gcgcttttac
     4981 tgtcgggttg ctcgatcatt tgtatccatt tgtattatca tggtgccata gcttgtatta
     5041 taactattta cgttaccttt gtttgtgaat ccacgccatg tggtgacgta gtgataccac
     5101 tatgaaacga atgttctgat tttaggtctg agggaggcgt catgaaaata ggattttcgc
     5161 aatactattc agtaagttat gaagtgtttt tttgagagat aaattgcaaa atgtgatcta
     5221 ccgcacactt tgccactcag gtatcgaagc gaatgtctac gcttaataga cagccgggca
     5281 acacccgtat cttttacgac gcaagccgga ggtccttgtc attatgctca accagaaatt
     5341 aaaccccacg ccttctgaag atctgactat tgatgtcgat ctgttttatg aaacagaccc
     5401 gtgcgagtta aagctggatg aaatgatcga ggcggaaccg gagccggaga tgatcgaggg
     5461 gcttcccgcc tctgacgccc tgacccctgc cgatcggtat ctcgaactgt tcgagcatgt
     5521 acagtcaaca aaactgtttc cagacagtaa aacgttcccg gactgcgcgc cgaagatgga
     5581 cccgcttgat atcctgatcc gctaccgtaa ggtcagacgc caccgtgatt ttgacttacg
     5641 ccgcttcgtc gagaaccatt tctggctacc ggaaacctta tccagcgagt atgtctctaa
     5701 ccccgaaaac tcgctcaaag aacatattga ccagctttgg ccgatactga cgcgcgaacc
     5761 gcaggatcat attccgtggt cttcgctgct ggcgctgccg caatcctata tcgtgccggg
     5821 aggccgtttt agcgaaacct attattggga ctcttatttt accatgctgg gtctggcgga
     5881 aagcgggcgc gaagacttac ttaaatgtat ggcggataat ttcgcctgga tgattgaaaa
     5941 ctatggtcat attcccaacg gcaaccgcac ctattatctg agccgctcgc agccgccggt
     6001 tttcgccctg atggttgaac tgttcgaaga agatggcgtg cgcggcgcgc ggcgttatct
     6061 cgaccatctc aaaatggaat acgccttctg gatggacggc gccgaatcgc tggcgctcaa
     6121 ccaggcttat cgccacgttg tgcggatgcc ggacggttcc ctgctgaacc gctactggga
     6181 cgatcgcgac acgccgcgcg acgagtcctg gctggaagat gtcgaaaccg caaaacattc
     6241 cggtcgtccg cccaatgaag tctaccggga tttgcgcgcc ggggcggcgt ccggctggga
     6301 ctattcttca cgctggctac gcgatgcggg ccggcttgcc agcatacgta caactcagtt
     6361 tatccctatc gatttgaacg cttttctgta taaactggag agcgctatcg ccaatatttc
     6421 agcgctgaaa ggcgaacgtg acaccgaggc gctatttcgc cagaaagcca gcgatcgacg
     6481 cgccgccgtg aaccattatt tgtgggatga tgaaaacggc tgttatcggg actatgactg
     6541 gcgacgcgaa gaaatggcgc tcttttccgc cgccagtatc gtgccgctgt atgtcggtat
     6601 ggcgaaccat gagcaggccg accgtctggc aaatgtagta cgcagccgtc tgttaacgcc
     6661 cggcgggatt atggcgaccg aatacgaaac cggcgaacag tgggataaac cgaacggctg
     6721 ggcgccgctg caatggatgg cgattcaggg cttcaaacgg tatggcgacg atatgctggg
     6781 cgatgaaatc gcccataact ggttaaaaac ggtgaaccat ttttatcagg agcaccataa
     6841 actgatcgag aaataccata tttccggcgg tacgccccgc gaaggcggcg ggggcgagta
     6901 tccgctacag gatgggttcg gctggaccaa tggcgtggtg cgccgcctga ttggccttta
     6961 cggagagcct taacctgctc cgggctcagt gaatcgcatc ataaatggct gactgaattt
     7021 tcagccattt tttattgtct gcgctgggcc gggcctgagc gcgcagctgg gcctgctccg
     7081 tatcgtactg ctggcgcgtc acaacagccg gaacggtgca aaacgtttgc aaataggttt
     7141 tatgcatcgc ggtcagcggc gcgccgctcg acatgtcatg acttaacgtt gtgataaatc
     7201 gtcggcaggg tttgacctca tccatcagcg cgggataacg caacaacagt tgcagcacct
     7261 cggtatgtcc tgccgcaaac gcctgctccg tccacgcgag ctgccagttc attccgccct
     7321 ggaggaacag cgccgtcacc cgcgtatcat tgcgctctat cgccgcccgc atggtaaacg
     7381 catcccaggt aatccccata tgattgagcg tttcccgcgc ggaaggcgcc tcgcgcggcg
     7441 gttcatcctg cgccattgcg ggagcttgcc cgttatcgga gcttggcgat gacgaactaa
     7501 atagccagaa cgcgcccgcc agtatcgcca gcgtcatgac gccaaccccg ccccacaaag
     7561 cgccggaaat aagttgctca cgctcttcag gcgtacgcgg aggccgctta cgcggtggtt
     7621 ctatgctctc gctaatctca tgcttatctc ccccggcctg ccgatcttta agccgcgcgg
     7681 tttcccagaa ctggcgcaat tcacgttcat ccgccagcag aaacgaagcg ggattcacgc
     7741 gggtacgttt ttcggcatag gcgcgctgga tgggccgaac gatttgctga tactgaacgt
     7801 ttagcagcat aagctgcgct gaggtgagcg gctgcctggc gataacctcg tttcgcgcga
     7861 ggcggcaatc atccagaaac atacgcagag tggtgcgcga ctcggcgaac agcgttaacg
     7921 ctgaggcgtc attaaaaatt ctgacgtaat gacgagcaaa caatttttta tcgaccacca
     7981 taagcgccag ttcgctaaac aacatgccct ccagcgcatg ttgatcttct ccctgtttta
     8041 accactggcg caaacggtcc gggccaaaat gttgcttgag gtagtgattc agggacgccc
     8101 gatccggcca tgcgcgcgca ataagcgctt ttaacgtcag ttctatcgcc cgaagctgac
     8161 gctgcgcctc aagatgcgcc tcctggtcgg ggtcttccag ctcagtttga tacgtcagta
     8221 gcggctgctg ctgacgtaga tgttccagcg aggtgacaaa acgcaacgcg gcaaggagtt
     8281 gattttcgct cacctcttgc ccgctgtcat actggggaac atgctgctga agatgacgca
     8341 gttgcagcat aaactggctc aactgcgcgt catttatccg caattttttc gccaccgcgc
     8401 cccaaccgcc caggttaaga cgcgcctgct caagttgttc catgaaccac cggggctctt
     8461 ttccctctgt ggtatgaata cccagcagca gcaggatttc tattgatgcc tggcggataa
     8521 tccccaggct atgttcaaaa ggcg
//
LOCUS       DAJVBX010000193         8500 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.193, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000193 DAJVBX010000000
VERSION     DAJVBX010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 8500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8500
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.193"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(38..2029)
                     /gene="tkt"
                     /locus_tag="OPV72_003758"
     CDS             complement(38..2029)
                     /gene="tkt"
                     /locus_tag="OPV72_003758"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HCR9915942.1"
                     /translation="MSSRKELANAIRALSMDAVQKAKSGHPGAPMGMADIAEVLWRDF
                     LNHNPTNPSWADRDRFVLSNGHGSMLIYSLLHLTGYDLPMSELQNFRQLHSKTPGHPE
                     VGYTAGVETTTGPLGQGIANAVGMAIAEKTLAAQFNRPGHDIVDHFTYVFMGDGCMME
                     GISHEVCSLAGTLKLGKLIAFYDDNGISIDGHVEGWFTDDTAKRFEAYGWHVIRGIDG
                     HDADAIKRATEEARAVTDKPSLLMCKTIIGFGSPNKQGTHDSHGAPLGDAEIALTREQ
                     LGWKYAPFEIPSEIYAQWDAKEAGQAKESAWNEKFAAYEKAFPQEAAEFTRRMKGDMP
                     ADFNAKANEFIAKLQANPSKIASRKASQNAIEAFGPLLPEFLGGSADLAPSNLTLWSG
                     SKAINEDAAGNYIHYGVREFGMTAIANGIALHGGFLPYTSTFLMFVEYARNAVRMAAL
                     MKQRQVMVYTHDSIGLGEDGPTHQPVEQVASLRVTPNMSTWRPCDQVESAVAWKYGVE
                     RQDGPTALILSRQNLAQQERTEEQLANIARGGYVLKDCAGQPQIIFIATGSEVELAVA
                     AYEKLTAEGVKARVVSMPSTDAFDKQDAAYRESVLPKAVSARVAIEAGIADYWFKYVG
                     LNGAIVGMTTFGESAPAELLFEEFGFTVDNVIAKAKALL"
     gene            2305..3063
                     /locus_tag="OPV72_003759"
     CDS             2305..3063
                     /locus_tag="OPV72_003759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HCR9915943.1"
                     /translation="MKIRALLLALGMATVLTGCQNMDSNGLLSSGAEAFQAYTLSDAQ
                     VKALSDQSCQELDSKAKIAPASSEYTKRLAKIAAALGDNINGQPVNYKVYETKDVNAF
                     AMANGCIRVYSGLMDMMTDNEVEAVIGHEMGHVALGHVKKGMQVALGTNAVRVAAASA
                     GGVVGSLSQSQLGDLGEKLVNSQFSQRQESEADDYSYDLLRKRGISPAGLATSFEKLA
                     KLEAGRQSSMFDDHPASAARAQHVRDRMSADGIK"
     gene            complement(3164..4084)
                     /gene="speB"
                     /locus_tag="OPV72_003760"
     CDS             complement(3164..4084)
                     /gene="speB"
                     /locus_tag="OPV72_003760"
                     /EC_number="3.5.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatinase"
                     /protein_id="HCR9915944.1"
                     /translation="MSTLGHQYDNSLVSNAFGFLRLPMNFQPYDSDADWVITGVPFDM
                     ATSGRAGGRHGPAAIRQVSTNLAWEHHRFPWNFDMRERLNVVDCGDLVYAFGDAREMS
                     EKLQAHAEKLLSAGKRMLSFGGDHFVTLPLLRAHAKHFGKMALVHFDAHTDTYANGCE
                     FDHGTMFYTAPKEGLIDPHHSVQIGIRTEFDKDNGFTVLDACQVNDRGVDDILAQVKQ
                     IVGDMPVYLTFDIDCLDPAFAPGTGTPVIGGLTSDRAIKLVRGLKDLNIVGMDVVEVA
                     PAYDQSEITALAAATLALEMLYIQAAKKGE"
     gene            complement(4312..6288)
                     /gene="speA"
                     /locus_tag="OPV72_003761"
     CDS             complement(4312..6288)
                     /gene="speA"
                     /locus_tag="OPV72_003761"
                     /EC_number="4.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic arginine decarboxylase"
                     /protein_id="HCR9915945.1"
                     /translation="MSDDMSMGSPSSAGEQGVLRSMQEVAMSSQEASKMLRTYNIAWW
                     GNNYYDVNELGHISVCPDPDVPEARVDLAKLVKAREAQGQRLPALFCFPQILQHRLRS
                     INAAFKRARESYGYNGDYFLVYPIKVNQHRRVIESLIHSGEPLGLEAGSKAELMAVLA
                     HAGMTRSVIVCNGYKDREYIRLALIGEKMGHKVYLVIEKMSEIAIVLEEAERLNVVPR
                     LGVRARLASQGSGKWQSSGGEKSKFGLAATQVLQLVETLRDAGRLDSLQLLHFHLGSQ
                     MANIRDIATGVRESARFYVELHKLGVNIQCFDVGGGLGVDYEGTRSQSDCSVNYGLNE
                     YANNIIWAIGDACEEHGLPHPTVITESGRAVTAHHTVLVSNIIGVERNEYTDPTAPAE
                     DAPRALQNLWETWQEMHKPGTRRSLREWLHDSQMDLHDIHIGYSSGAFSLQERAWAEQ
                     LYLSMCHEVQKQLDPQNRAHRPIIDELQERMADKMYVNFSLFQSMPDAWGIDQLFPVL
                     PLEGLDQVPERRAVLLDITCDSDGAIDHYIDGDGIATTMPMPEYDPENPPMLGFFMVG
                     AYQEILGNMHNLFGDTEAVDVFVFPDGSVEVELSDEGDTVADMLQYVQLDPKTLLTHF
                     RDQVKQTDLDDALQQQFLEEFEAGLYGYTYLEDE"
     gene            complement(6297..6428)
                     /gene="yqgB"
                     /locus_tag="OPV72_003762"
     CDS             complement(6297..6428)
                     /gene="yqgB"
                     /locus_tag="OPV72_003762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid stress response protein YqgB"
                     /protein_id="HCR9915946.1"
                     /translation="MKKKPVAQAEHQRYLLENPLVYGLLSRLRIAIVVNCFTLANKN"
     gene            6562..6726
                     /locus_tag="OPV72_003763"
     CDS             6562..6726
                     /locus_tag="OPV72_003763"
                     /inference="COORDINATES: protein motif:HMM:NF037550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915947.1"
                     /translation="MGITSAGMQSRDADCGRHARTRTMRQIQQNTTVHYLVSPPRPPR
                     KTNPQAKATF"
     gene            complement(6723..7022)
                     /locus_tag="OPV72_003764"
     CDS             complement(6723..7022)
                     /locus_tag="OPV72_003764"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915948.1"
                     /translation="MTEDSTMSLKVTNTGSLSVNQYGWINIWTAILGHFFAQFPAFFE
                     GRRNVGQNQAVNVSDNADIMRIYALLFFCVLGIKRDARLIQKHTTFSSCRHFQPG"
     gene            7078..8232
                     /gene="metK"
                     /locus_tag="OPV72_003765"
     CDS             7078..8232
                     /gene="metK"
                     /locus_tag="OPV72_003765"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HCR9915949.1"
                     /translation="MAKHLFTSESVSEGHPDKIADQISDAVLDAILQQDPKARVACET
                     YVKTGMVLVGGEITTSAWVDIEEITRNTVREIGYVHSDMGFDANSCAVLSAIGKQSPD
                     INQGVDRADPLEQGAGDQGLMFGYATNETDVLMPAPITYAHRLVQRQAEVRKNGTLPW
                     LRPDAKSQVTFQYDDGKIVGIDAVVLSTQHAEDIDQKSLQEAVMEEIIKPILPSEWLN
                     TSTKFFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAA
                     YAARYVAKNIVAAGLADRCEIQVSYAIGVAEPTSIMVETFGTEKVPAEQLILLVREFF
                     DLRPYGLIQMLDLLHPIYKETAAYGHFGRENFPWEKTDKAQLLRDAAGLK"
BASE COUNT         1998 a         2378 c         2246 g         1878 t
ORIGIN      
        1 ggtcgccgaa gcgacccgtt ttatgccgta ttaaggatta cagcagcgct ttcgctttgg
       61 cgatcacgtt gtccaccgtg aagccaaact cttcaaacag cagctctgcc ggggcggatt
      121 caccgaaggt ggtcatcccg acaatagcgc cgttcaggcc gacgtatttg aaccagtagt
      181 cagcgatacc cgcttcaatc gccacacgcg cagagaccgc tttcggcagc acggattcac
      241 ggtaggccgc atcctgcttg tcgaacgcgt cggtggacgg catggaaacc acgcgcgcct
      301 tcacgccttc ggcagtcagt ttttcgtagg cggcaaccgc cagctcaacc tcagaaccgg
      361 tcgcaatgaa gataatctgc ggctggcccg cacaatcttt cagtacgtaa ccaccgcggg
      421 cgatattcgc cagttgctct tcagtacgct cctgctgcgc caggttctga cgggacagaa
      481 tcagcgcggt tgggccatcc tgacgctcta cgccatattt ccacgccacc gcggattcca
      541 cctggtcgca cggacgccat gtggacatgt tcggcgttac gcgcaggctt gccacctgct
      601 cgaccggctg gtgcgtcggg ccatcttcgc ccagaccgat ggagtcgtgg gtatagacca
      661 tcacctgacg ctgtttcatc aacgctgcca tacgcactgc gttacgggca tattcgacga
      721 acatcaggaa ggtggaggtg tacggcagga aaccgccgtg cagggcgata ccgttggcga
      781 tagcggtcat accgaattcg cgcacaccgt aatgaatgta gttacctgcg gcatcttcgt
      841 taatcgcttt cgaaccggac cacagggtca ggttagacgg tgccaggtca gcggagccgc
      901 cgaggaattc cggcaacagc ggaccgaagg cttcgatggc attctgggac gctttacggc
      961 tggcgatttt ggatggattc gcctgcagtt tagcgatgaa ctcattcgct ttcgcattga
     1021 agtcagccgg catgtcgcct ttcatacgac gagtgaattc agcagcttcc tgcgggaagg
     1081 ctttctcata agccgcgaat ttctcattcc atgcagactc tttcgcctgg ccggcttctt
     1141 tcgcatccca ctgggcgtag atttcagacg ggatttcgaa cggcgcgtat ttccagccca
     1201 actgttcgcg ggtcagcgcg atttccgcgt cgcccagcgg cgcgccgtgg gaatcgtggg
     1261 taccctgttt gttcggcgaa ccgaagccga tgatggtttt gcacatcagc agggacggtt
     1321 tgtcagtcac ggcgcgagct tcttccgtgg cacgtttaat ggcgtcggca tcgtgaccgt
     1381 caatgccacg gataacgtgc cagccgtagg cttcaaaacg tttcgcggtg tcatcggtga
     1441 accagccttc aacatgacca tcgatagaga taccgttgtc atcatagaac gcgatcagtt
     1501 tgcccagttt cagagtacca gccagagagc acacttcgtg agaaatgcct tccatcatgc
     1561 agccgtcgcc cataaagacg taggtgaagt ggtcaacgat gtcgtggcca ggacggttaa
     1621 actgcgccgc cagagttttc tcggcaatcg ccatcccgac ggcgttggca ataccctgcc
     1681 ccagcgggcc ggtagtggtt tcaacgccag cggtgtagcc cacttccggg tgaccagggg
     1741 tttttgaatg tagctgacgg aaattctgca gttcggacat cggcaggtca taaccggtga
     1801 ggtgcagcag gctgtaaatc agcattgagc cgtggccatt ggacagcacg aagcggtcgc
     1861 ggtcggccca agacgggttg gtcgggttgt ggttcaggaa atcacgccac aggacttcgg
     1921 caatgtcagc catacccatc ggggcacccg ggtgaccgga tttggctttc tgtactgcgt
     1981 ccatgctcag cgcacgaata gcattggcaa gctctttacg tgaggacatt ttgactccag
     2041 atcggatgtt gaaaggccat gcccgtaacg acttgacgac agcgcgtttt gggctacgcc
     2101 ggaaaatttg ccaacaattt accccaagcc gcgcgtcatg tacatggaac atccttttac
     2161 cgcttcagaa atctccggat cgtgctcgca tgttgcgcaa ttagctaact tgcctgccac
     2221 gcttttcttt atacttaacc caggcgctaa ttcatctgca acgggcgcat ttcaaaataa
     2281 tattaattcg tatggaagag aaaaatgaaa attcgcgctt tactgcttgc tttgggcatg
     2341 gcgacggtgc tgaccggttg ccagaatatg gactctaatg gactgctttc ttcgggcgct
     2401 gaagcttttc aggcctatac gttaagcgat gcgcaggtaa aagcgttgag cgatcaatcc
     2461 tgtcaagagc tcgacagcaa agcgaaaatc gcgccggcga gcagcgaata cactaaacga
     2521 ctggcaaaaa ttgccgccgc gctgggggat aacattaacg gccagccggt gaactataaa
     2581 gtttacgaga cgaaagacgt caacgcgttt gccatggcga acggttgtat ccgcgtctac
     2641 agcggactga tggatatgat gaccgacaac gaagttgaag ccgtgatcgg tcatgaaatg
     2701 ggccatgtcg ctctgggtca tgtaaagaaa gggatgcagg tcgcgctggg cactaacgcc
     2761 gtgcgcgttg cggcggcatc ggcaggaggc gttgtcggca gcctgtcgca atcacagctt
     2821 ggcgatcttg gcgaaaaact ggtgaactcg cagttctctc agcgtcagga gtccgaagcg
     2881 gatgattatt cttacgatct gttgcgcaaa cgcggtatca gtccggcagg actcgccacc
     2941 agctttgaga aactggcaaa actggaagcg ggtcgtcaaa gctcaatgtt cgacgatcac
     3001 ccggcgtccg ccgcacgcgc acagcatgtg cgcgatcgta tgagcgcgga cgggatcaaa
     3061 taatccccga acagtgccgg atggcggcgt gaacgcctta tccggcctac acaggcccgg
     3121 taagcgtagg ccggataagc gcagtgccat ccggcaaaac aacttactcg cccttcttcg
     3181 ccgcctggat atagagcatt tctaatgcca gcgtcgcggc cgccagagcg gtgatctccg
     3241 actgatcgta agccggcgcg acttccacta catccatacc gacaatgttc agatctttca
     3301 gaccacgtac cagcttaatg gcgcgatcgg aggtcaaacc accgatcacc ggcgtaccgg
     3361 tgccaggcgc aaacgccggg tccagacagt cgatatcaaa ggtcagatag accggcatat
     3421 cgccgacgat ctgtttcacc tgagcgagaa tatcatccac gccgcgatcg ttgacctggc
     3481 aggcatccag cacggtaaag ccattgtctt tgtcaaactc agtgcgaata ccgatctgta
     3541 ccgaatgatg cggatcgatc aggccttctt tcggcgcggt gtagaacatc gtgccgtgat
     3601 cgaattcgca gccgttagcg taggtatcgg tatgcgcgtc aaaatgtacc agcgccattt
     3661 tgccaaaatg tttcgcgtgg gcgcgcagca gcggcagcgt gacgaagtgg tcgccgccga
     3721 aagagagcat acgcttgcct gcagacagca gtttttcagc gtgcgcctgt aatttttcgc
     3781 tcatttcacg ggcatcgcca aacgcataca ccagatcgcc gcagtccacg acgttcaggc
     3841 gctcgcgcat gtcaaaattc cacgggaaac ggtgatgttc ccaggcgagg ttggtcgaca
     3901 cctgacggat cgccgccggg ccatgacggc cgccagcgcg accggacgtt gccatatcaa
     3961 acggtacgcc agtgatcacc cagtcggcat cgctgtcata cggctggaag ttcattggca
     4021 gacgtaaaaa accaaacgca ttagaaacca gtgagttatc gtactgatga cctaaagtgc
     4081 tcatgtcctg acctctttta gagtcgttgc attaaaacag atgaaaaaaa tcccctccgc
     4141 gtcgttaaac ccgacgagga agggattgat ttgtaaatcg ctattgcagc gaattatcgc
     4201 cgttaattca tacgggttca agtgagtata gcattctgcc gggtggcggc tttaccttat
     4261 ccagcctgca ttcgtaggcc cggtaagcgc agcgccgccg ggcatcaacg gctactcatc
     4321 ttcaagataa gtataaccgt acagtcccgc ttcaaattcc tcaaggaact gctgctgcaa
     4381 cgcatcgtcc agatccgtct gttttacctg gtcgcggaaa tgcgttaata gcgttttcgg
     4441 atccagttgc acatattgca gcatatccgc aacggtatcg ccttcgtccg acaactcaac
     4501 ctcgacacta ccatccggga agacaaacac gtcaaccgct tcagtatcgc caaacaggtt
     4561 gtgcatgtta ccgaggatct cctgataggc gccgaccata aagaagccga gcatcggcgg
     4621 attctctgga tcgtattccg gcatcggcat cgtcgtggcg ataccgtcgc catcgatata
     4681 gtggtcgata gcgccatcgg aatcacaggt aatatccagc agcacggcac gacgttccgg
     4741 tacctgatct aacccttcca gcggcagcac cggaaagagc tgatcgattc cccacgcgtc
     4801 cggcatcgac tggaacagcg agaagttgac gtacattttg tccgccatcc gctcttgcag
     4861 ttcgtcgata atcgggcgat gcgcacggtt ttgcgggtcc agttgcttct gcacttcatg
     4921 gcacatgctg agataaagtt gctccgccca ggcgcgctcc tgcaaactaa acgcgccgga
     4981 agagtagccg atatgaatat cgtgcagatc catttggcta tcatgcagcc attcacgcag
     5041 cgagcggcgg gtgccaggct tatgcatctc ctgccaggtt tcccacagat tttgcagcgc
     5101 gcgcggcgca tcttcagcag gggcggtcgg atccgtgtat tcgttacgct ccacgccgat
     5161 aatgttagag accagtaccg tatggtgcgc agtgacggcg cgcccagact cggtaatcac
     5221 cgtcggatgc ggtaaaccat gctcttcgca ggcatcgcca atcgcccaga tgatgttatt
     5281 ggcatattcg ttcaggccat agttcaccga acagtcggac tgcgagcggg taccttcata
     5341 atccacgccc agaccgccgc ccacgtcgaa gcactggata ttaacgccca gcttatgcag
     5401 ctcaacatag aaacgcgcgg actcgcgcac gccggtcgcg atatcgcgaa tgttcgccat
     5461 ctgcgatccc aggtggaagt gcaacagttg cagactgtcc agacgcccag cgtcacgcag
     5521 ggtctccacc agttgcagca cctgcgtcgc cgccaggccg aattttgatt tttcgccgcc
     5581 ggaggattgc cacttaccgg acccctgaga ggccagacgc gcacgcacgc ccaggcgagg
     5641 aaccacgttc aggcgctcgg cctcttccag cacaatcgcg atttcagaca tcttttcgat
     5701 gaccagataa accttatggc ccatcttctc gccaatcagc gccagccgaa tatattcacg
     5761 gtctttataa ccattacaga cgatcacgct acgggtcatg ccggcatgcg ccagcaccgc
     5821 catcaattcc gctttcgacc ccgcttccag ccccaacggt tcaccggaat ggataaggga
     5881 ctcgatcacg cggcgatgct gattgacctt aatcggataa acgaggaagt agtcgccgtt
     5941 ataaccgtaa gattcacgcg cacgcttaaa cgccgcgtta attgaacgca aacggtgttg
     6001 caggatctgc gggaagcaga acagcgccgg cagacgctga ccttgcgctt cgcgcgcttt
     6061 caccagtttg gcaagatcga cacgcgcttc cggtacgtcg ggatcggggc atacgctaat
     6121 atggcccagc tcgttgacgt cgtagtagtt attgccccac caggcaatat tgtaagtgcg
     6181 cagcatcttg ctggcttcct gggagctcat tgcaacctcc tgcatggagc gtagtacacc
     6241 ctgttcgcct gctgacgaag gcgaacccat agacatgtcg tcagacatag cgaacctcaa
     6301 tttttattag caagtgtaaa acagttgact actatcgcaa tccgaagacg cgataacaac
     6361 ccatagacaa gcggattttc cagcagatag cgctgatgct ccgcctgcgc gaccggtttc
     6421 tttttcatat cattgtaaac acgtaaccga actcacagat aacggttcgg cgaaaccacg
     6481 agaaaactct tgcgttaaca agagcgccct tgttcagtct tcagcgccat tgccggctct
     6541 ggaatcctga gaagcgccga gatgggtata acatcggcag gtatgcaaag cagagatgca
     6601 gattgcggga gacatgcgcg caccagaacg atgcgacaga ttcagcagaa tacaacggtt
     6661 cattatctcg tatcacctcc acggccgcct cgtaagacga acccacaagc caaagcaacg
     6721 ttttaacccg gctggaagtg gcgacacgaa gaaaacgtcg tgtgcttttg tatgagccgc
     6781 gcgtcgcgtt ttatacccag aacgcagaaa aaaagcaaag cataaatgcg cataatgtca
     6841 gcattatcag aaacgtttac cgcctgattt tgaccgacat tgcgacggcc ttcaaaaaaa
     6901 gctggaaatt gggcgaagaa gtgacctaaa atagccgtcc agatgttaat ccatccatac
     6961 tgattaacac tcagactgcc agtgttagta accttcagac tcatggtaga atcttctgtc
     7021 atgactattc cgcacaacag tttgagctaa ctaaattctc cttaggtgaa attaaatatg
     7081 gcaaaacacc tttttacgtc tgagtccgta tcagaagggc atcctgacaa aatcgcagac
     7141 caaatctctg atgccgtgtt ggacgctatc ctgcaacagg atccgaaagc acgcgtcgcc
     7201 tgtgaaacct acgttaaaac cggcatggtt ttagttggcg gtgagatcac caccagcgcc
     7261 tgggtcgata tcgaagagat tacccgtaat acggtgcgcg aaattggcta tgtgcattcc
     7321 gacatgggct ttgacgccaa ctcttgcgcg gtactgagcg caattggcaa acagtctccg
     7381 gatatcaacc agggcgttga ccgcgcagac ccgctggaac aaggcgcggg cgaccagggc
     7441 ctgatgtttg gctacgcgac aaatgaaacc gacgtactga tgcctgcgcc aatcacctac
     7501 gcgcaccgtc tggtacagcg tcaggctgaa gtgcgtaaaa atggcaccct gccatggttg
     7561 cgtccggatg caaaaagcca ggtcactttc cagtatgacg acggcaaaat cgtcggtatc
     7621 gacgccgtgg ttctctctac gcagcacgca gaagatatcg accaaaaatc gctgcaagaa
     7681 gcggtgatgg aagagatcat caaacccatt ctgccgtctg aatggttaaa tacgtccact
     7741 aagtttttta tcaacccaac cgggcgtttt gttatcggcg gcccgatggg cgattgtggt
     7801 ctgaccggtc gtaagatcat cgttgatacc tacggcggta tggcgcgtca cggcggcggc
     7861 gccttctccg gtaaagatcc gtctaaagtt gaccgttctg cagcttacgc tgcgcgttat
     7921 gtcgcgaaaa acatcgtggc ggcaggtctg gcggatcgct gtgaaatcca ggtctcctac
     7981 gctatcggcg tagcggagcc gacgtccatc atggtggaaa cgttcggtac tgaaaaagtg
     8041 cctgctgaac agttgattct gctggtgcgc gaattcttcg acctgcgccc gtacggcttg
     8101 attcagatgc tggatctgct gcacccgatc tacaaagaaa ctgcggctta cggccacttc
     8161 ggtcgcgaaa acttcccatg ggaaaaaacc gacaaagcgc aactgctgcg cgatgctgcc
     8221 ggtctgaaat aatcgcccgc gcctgacgct gtttttcagt caggtaaacc ataccgtact
     8281 tatcaaggcc agcgccctgc tggcctttat cattgctgat acacgcaacg ttattagatg
     8341 ttccagcgtg tatttatact gacctttttg tgatgcgcag cacaatccgc tctcctcttt
     8401 cgtttcttcg actacacttt tcatcattca gtttcagcag ctatgaaagc ggttacattc
     8461 attttcattg agaactgacc acctcactgt cggtatgcta
//
LOCUS       DAJVBX010000194         8451 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.194, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000194 DAJVBX010000000
VERSION     DAJVBX010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 8451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8451
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.194"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            249..2012
                     /locus_tag="OPV72_003766"
                     /pseudo
     CDS             249..2012
                     /locus_tag="OPV72_003766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459238.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="chitinase"
     gene            2088..4229
                     /gene="ldcC"
                     /locus_tag="OPV72_003767"
     CDS             2088..4229
                     /gene="ldcC"
                     /locus_tag="OPV72_003767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine decarboxylase LdcC"
                     /protein_id="HCR9915950.1"
                     /translation="MNIIAIMGPHGVYYKDEPIKELERALQSLGFQIIWPQNSVDLLK
                     FIEHNPRICGVIFDWDEYSLDLCSEINQLNEYLPLYAFINTNSTLDVSVHDMRMALWF
                     FEYALGLAEDIATRIHQYTNEYLDNITPPFTKALFTYAKEGKYTFCTPGHMAGTVYQK
                     SPPGCLFYDFFGGNTLKADVSISVTELGSLLDHTGPHLEAEEYIARTFGAEQSYMVTN
                     GTSTSNKIVGMYAAPAGSTLLIDRNCHKSLAHLLMMSDVVPLWLKPTRNALGILGGIP
                     KREFTRDSIARKVAETAQAQWPVHAVITNSTYDGLLYNTNWIKQMLDVPSIHFDSAWV
                     PYTHFHPIYQGKSGMSGDRVPGKVIFETQSTHKMLAAFSQASLIHIKGEYDEETFNEA
                     FMMHTSTSPSYPIVASIETAAAMLRGNPGKRLINRSVERALHFRKEVQRLREESDSWF
                     FDIWQPEEVDEAECWPVTPGETWHGFTDADDDHMFLDPVKVTILTPGMDEQGNMSEEG
                     IPAALVAKFLDERGVVVEKTGPYNLLFLFSIGIDKTRAMGLLRGLTEFKRAYDLNLRV
                     KNMLPDLYAEDPDFYRNMRIQDLAQGIHKLIRQHDLPELMLRAFEVLPEMIMTPHQAW
                     QRQIKGEVETVALDQLPGRVSANMILPYPPGVPLLMPGERITQQSRAVLDFLLMLCSI
                     GQHYPGFETDIHGAKRNEDGVYQVRVLKHAC"
     gene            4285..4674
                     /locus_tag="OPV72_003768"
     CDS             4285..4674
                     /locus_tag="OPV72_003768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCR9915951.1"
                     /translation="MLGLKQVHHIAIIATDYAVSKAFYCDILGFDLLSEAWREERDSW
                     KGDLALNGQYVIELFSFPFPPARPSRPEACGLRHLAFSVENVENAVAHLEKHQVKCEP
                     IRIDPYTGKRFTFFNDPDGLPLELYEQ"
     gene            4737..6029
                     /gene="tilS"
                     /locus_tag="OPV72_003769"
     CDS             4737..6029
                     /gene="tilS"
                     /locus_tag="OPV72_003769"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HCR9915952.1"
                     /translation="MTTLTLNTSLLSSRRILAAFSGGLDSTVLLHQLVLWRERHPDVT
                     LRAIHIHHGLSPHADSWVRHCETVCERWQVPLVVERVTLADNGLGIEAHAREARYRAF
                     AQTLLPGEVLATAQHLDDQCETFLLALKRGSGPAGLSAMGERSPFAGTLLLRPLLRET
                     RKTLEQWAVRHGLCWIEDESNQDDAYDRNFLRLRALPLLQQRWPHFPAAVARSATLCA
                     EQERLLDELLASDLTDCITTEGTLRLSPLMSMSDVRRAAILRRWLAMRNAPMPSRDAL
                     ERIWQEVALARDDASPCLRFGDHEIRRYQSQLWWIKTVAGQHETTVAWPVWQTPLALP
                     AGLGTVQLVPGGELRRPREEESVSIRFKAPGLLHIVGRHGGRKLKKIWQEQGIPPWRR
                     DTTPLLFYGETLIAAAGVFVTREGAAEDKEGVSLVWHA"
     gene            complement(6113..6373)
                     /gene="rof"
                     /locus_tag="OPV72_003770"
     CDS             complement(6113..6373)
                     /gene="rof"
                     /locus_tag="OPV72_003770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rho-binding antiterminator"
                     /protein_id="HCR9915953.1"
                     /translation="MSMNETYQPINCDDYDSLELACMHHLILTLTLKDGEVLQAKAND
                     LILRKNVEYLLAEVSGESCELRLDKIASFSHPEIGTVVVSES"
     gene            complement(6360..6560)
                     /locus_tag="OPV72_003771"
     CDS             complement(6360..6560)
                     /locus_tag="OPV72_003771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaeP family protein"
                     /protein_id="HCR9915954.1"
                     /translation="MEKYCELVRKRYAEIASGDLGYVPDALGCVLKVLNEVAADSALS
                     ESVREKAAYAAANLLVSDYVNE"
     gene            6758..7303
                     /locus_tag="OPV72_003772"
     CDS             6758..7303
                     /locus_tag="OPV72_003772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaeQ family protein"
                     /protein_id="HCR9915955.1"
                     /translation="MALKATIYKAVVNVADLDRNRFLDAALTLARHPSETQERMMLRL
                     LAWIKYADERLQFTRGLSAEDEPEAWLRNDHLGIDLWIELGLPDERRIKKACTQASDV
                     ALFAYNSRAAQIWWQQHQSKCAQFANLSVWYLDDGQLAQLSEFADRTMTLQATIQDGA
                     IWLSDARNNLEIQLTAWQQPS"
     gene            7300..7722
                     /gene="arfB"
                     /locus_tag="OPV72_003773"
     CDS             7300..7722
                     /gene="arfB"
                     /locus_tag="OPV72_003773"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HCR9915956.1"
                     /translation="MIAISRTVSIADNELEITAIRAQGAGGQHVNKTSSAIHLRFDIR
                     ASGLPEYYKQRLLTASHHLISDDGVIIIKAQEFRSQELNREAAIARLVAVIKELTAEQ
                     KSRRATRPTRASKERRLSSKAQKSSVKALRGKIRRPLD"
     gene            7754..>8451
                     /gene="nlpE"
                     /locus_tag="OPV72_003774"
                     /gene_synonym="cutF"
     CDS             7754..>8451
                     /gene="nlpE"
                     /locus_tag="OPV72_003774"
                     /gene_synonym="cutF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006899150.1"
                     /note="NlpE, an outer membrane lipoprotein, interacts
                     directly with CpxA, the sensor histidine kinase of the Cpx
                     system for response to envelope stress; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response activation lipoprotein
                     NlpE"
                     /protein_id="HCR9915957.1"
                     /translation="MVRTAILSVAAACTLFALIGCNNRAEVDALQPAQAAELKPMQQS
                     WRGVLPCADCEGIETSLFLEKDGTWVMNERYQGVREEPSSFASYGTWARTADKLVLTD
                     SNGEKSYYRAKGNALEMLDREGNPVASQLNYTLVPVTASLPVTPMPLRGMYVYRADAA
                     TFTDCATGKRLPVASNAQLERGYLAAKGEAEKPVLLTVEGHFVFAANPDTGEPVKTLI
                     ADKNVKFAPGKDCT"
BASE COUNT         1982 a         2120 c         2434 g         1915 t
ORIGIN      
        1 cgtaagtaac gaagtttgat gcaaatgtca gatcgtatgc gcctgttagg gcgcggctgg
       61 taagagagcc ttacaggcgc atcagaaaaa cctccggcta tgccggagga tatttatttt
      121 ggacgaggaa aaatgagacg ccgatgagct gatgtgatta aacgcaacgg catgttctcc
      181 ctgacactgt agcaactgcc aggcgtgtgg ccagggcagg cagtgaacta cccttcaagg
      241 agaaaattat gggattgcaa aaaacactgg cgctcagcgc cgtagcggca gggatcatgt
      301 tgagcttatc cggtgcgcag gccgcgccgc tgcttagcag tagtgagcca atgaccatta
      361 acgccagcga tctggcggcg aaagagaaag cgctgacgga ttttccgtta atggaggcag
      421 tgaaatcctc tatccagacg ttggataaca gcgcggtcga acaaatcgaa ccggggcgcg
      481 ccgctaaccc ggcaaacgta aaacgcgttg aaagtattct gaaagaggcc gactgggatt
      541 atctgttccc gatgcgcgcg ccggaataca cttactctaa cttcctgaaa gcgataggta
      601 aattcccggc ggtttgtggt acctacaccg atggacgcga tagcgacgct atctgccgta
      661 aaaccctggc tactatgttt gcgcattttg cccaggagac gggcggtcac gaaagctggc
      721 gtgacattcc ggaatggcgt caggcgctgg tctatctgcg cgaagtcggc tgaacagaag
      781 ggcaaaaagg cggctacaac ggcgaatgta acccggatgt atggcagggc cagacctggc
      841 cgtgcggtaa agataaggac ggcgatttcc tcagctattt tggccgcggg gcaaaacagc
      901 tttcttataa ctacaactat gggcctttct ctgacgcgat gtatggcgac gttcgccctc
      961 tgctggataa acccgagctg gtggcggata cctggatgaa cctggcgagc gccgtcttct
     1021 tctttgtgta tccgcagccg ccgaagccgt ctatgctaca tgtgattgac ggtacctggc
     1081 agccaaacga tcgcgataaa gcaaacggcc tggtatcagg tttcggcgtc actattcaga
     1141 tcatcaatgg cggcgtggag tgcggcggcg cagatgagaa tgcgcagtcg cttaaccgta
     1201 tcgcctacta caaagagttt gccaactacc tgaaagtgcc ggtgccggct gacgaagtgt
     1261 tgggctgtaa aaagatgaag cagttcgatg aaggcggcgc tggcgcgtta ccgatctatt
     1321 gggaacaaga ctggggctgg agcgccgata ctgcggacgg taaaacctat tcctgccagt
     1381 tagttggata tcagacgccg tataccgcct ttaaagaggg cgactacacg aaatgtgtac
     1441 agcattattt caacgttaat gtcgtcgatg ataacggaac cactgaaccg gatgtcacgc
     1501 caactccggc gccagtgacg gatgaaaacg tggcaccagt cgcgcgcatt gccgggccgg
     1561 tcggggcggt ggaagccggt agccaggttt cactcaacgc ggaaggatcg accgacgcga
     1621 atggcgacaa gctcacctat acctggatgt cgcaggatgg caaaacgctg agcggccagg
     1681 ataaagccgt tgtgattttc aacgcgccgg atgtcactca gaacacccag tatgtggtga
     1741 atctgaccgt tagcgacggt acgctctcca gtacagcggt ttatacgctg aatgtgaaag
     1801 cgaaggccgc cgctgcggat gacgaagata agaccaccag ctaccctgcc tggagcagca
     1861 gccagaaatg gaatccgggc gacatcgtca acagtaatgg cgcattgtac cagtgcaaac
     1921 cgttcccgga aggctcatgg tgtaatgttg cgcctgccta ctatgagccc ggcgtaggga
     1981 ttgcctgggc cgatgcatgg aacgcattgt aataagataa atcctgtcgg tgctttgcat
     2041 cggcaggatt gttactatgc ttatctcagg ttttttcagg agaaagcatg aacatcatcg
     2101 ccattatggg gccgcacggg gtttattata aagatgaacc catcaaggag cttgagcgtg
     2161 cattacaatc cctgggattt caaattatct ggccgcaaaa tagcgttgac ttgttgaagt
     2221 ttattgaaca taacccgcgc atctgcggcg ttatttttga ctgggatgaa tacagtctcg
     2281 acctttgtag cgaaatcaac cagctaaatg aataccttcc tctctacgcc tttatcaata
     2341 ccaactccac gctggacgtt agcgttcacg atatgcgcat ggcgctgtgg ttttttgagt
     2401 atgcattggg gctggctgaa gatatcgcga cgcgcattca tcaatataca aacgaatatc
     2461 tcgataatat tacgccgccg tttaccaaag cgctgtttac ctacgccaaa gaaggaaaat
     2521 ataccttttg tacgccgggg catatggcgg gaacggtgta tcagaaaagc ccgccaggct
     2581 gtctgtttta tgactttttt ggcggcaata ccttaaaggc cgatgtgtcg atttcggtga
     2641 ctgaactggg atcgctgctg gatcacaccg ggccgcatct ggaagcggaa gagtatatcg
     2701 cccgtacttt tggcgccgag cagagttata tggtgacgaa cggtacgtcg acctcgaata
     2761 aaattgtcgg tatgtatgcc gcgcctgcgg gaagtacgct acttattgat cgtaattgcc
     2821 ataaatcgct ggcgcatttg ctgatgatga gcgatgtggt gcctctctgg ttgaagccga
     2881 cgcgcaatgc gctcggcatt ctcggcggta ttcctaagcg tgaatttacc cgcgacagca
     2941 ttgcgcgtaa ggtggcggaa accgcgcagg cgcaatggcc ggtgcatgcg gttatcacca
     3001 attcgactta cgatggtctg ctgtataaca ctaactggat caagcagatg ctggacgttc
     3061 cctcgatcca ttttgattcc gcctgggtac cctataccca tttccatccg atctaccagg
     3121 ggaaaagcgg gatgagcggc gatcgggtgc ccggaaaagt gattttcgaa acgcaatcca
     3181 cccataaaat gctggcggct ttttcgcagg cgtcgcttat tcatatcaaa ggggaatatg
     3241 acgaagagac gtttaacgaa gcgtttatga tgcacacttc tacatcgccg agctatccca
     3301 ttgtcgcctc tatcgagacc gcggcggcga tgctgcgcgg caatccaggg aaaagattga
     3361 ttaatcgttc ggtggaacgg gcgctccatt ttcgtaaaga agtacagcgg ttacgtgaag
     3421 agtccgatag ctggttcttt gatatctggc agccggaaga ggttgatgag gccgaatgct
     3481 ggccggtcac gccgggagaa acctggcatg gcttcaccga tgctgatgac gatcatatgt
     3541 tcctcgatcc ggttaaggtg acaatcctga cgccggggat ggatgaacag ggcaacatga
     3601 gcgaagaggg gatacccgcc gcgctggtgg cgaagttcct cgatgagcga ggcgtggtgg
     3661 tggaaaaaac cgggccgtat aatctgctgt ttttgttcag catagggatt gataagaccc
     3721 gtgcgatggg gctgctgcgc ggactgacgg aatttaaacg cgcctacgat cttaacctgc
     3781 gcgtcaaaaa tatgttgccg gatctgtatg cggaagatcc ggatttttat cgcaatatgc
     3841 gcattcagga tctggcgcag gggatccata aactgatccg ccagcacgat cttccggagc
     3901 tgatgctgcg ggcgttcgag gttttaccgg agatgatcat gaccccgcac caggcctggc
     3961 agcgtcagat caaaggtgag gtggaaaccg tggcgctcga tcaactgcca gggcgcgttt
     4021 ccgcgaatat gatcctgcct tatccgccag gcgttccgct gttgatgccc ggcgagagga
     4081 tcacgcaaca gagtcgggcc gtgctcgatt ttctgctgat gctctgttcg attggccagc
     4141 attatcccgg ttttgaaacg gatattcacg gcgcgaaacg gaatgaagac ggggtgtacc
     4201 aggtacgagt cttaaaacac gcctgttagc ttgcctgacg agaatgtgac gagtaacgta
     4261 ctgataatca ataaaggaga cgctatgctg ggattaaaac aggttcatca catcgcgatc
     4321 attgcgacag actatgcggt gagcaaggcg ttttattgcg atattctggg gttcgatctg
     4381 ctaagcgaag cctggcggga agagcgtgac tcgtggaagg gcgatttggc gctaaacggg
     4441 cagtatgtga ttgagctttt ctcttttccc ttccctccgg cgcgtccaag ccgacctgaa
     4501 gcctgcggtc tgcgccatct ggctttcagc gtggaaaatg tggaaaacgc cgttgcgcat
     4561 ctggaaaagc atcaggttaa gtgcgaaccg atacgcatcg atccgtatac cgggaagcgc
     4621 tttacttttt tcaacgatcc ggacggttta ccgcttgagc tgtatgagca gtaaggcttg
     4681 tcattaagac gctcgccagg taacgttgcc gggctaagtc actataagca tggatcatga
     4741 ccactctcac gttgaatacc tcgttactct cttctcgccg tattctggct gcctttagcg
     4801 gtggcctgga ttctacggtg cttctgcatc aactggtgtt gtggcgagaa cgccatcctg
     4861 acgtcacgct gcgtgctatc catattcatc acggtttaag ccctcatgct gatagctggg
     4921 tgcggcattg cgaaaccgta tgcgaacgct ggcaggttcc gctggtagtg gagcgggtga
     4981 cgttggcgga taatggcctg ggtatcgagg cccatgcgcg tgaagcgcgc taccgggcgt
     5041 tcgcacagac gctattgcct ggcgaagtgc tggcaaccgc gcagcacctt gacgatcagt
     5101 gtgaaacatt cctgctggcg ttaaagcgcg gcagcggtcc ggccggactt tccgcgatgg
     5161 gagaacgctc gccttttgcc ggaactctgc ttcttcgccc gctgttgaga gaaacgcgga
     5221 agacgctgga acagtgggct gtgcgtcatg gcttatgctg gattgaagat gaaagcaatc
     5281 aggatgacgc ctacgatcgc aattttttac gcctgcgcgc gcttccgctc ttacagcagc
     5341 gctggccgca ttttcctgcg gcggtagccc gtagcgcgac gctctgcgcc gagcaagaaa
     5401 ggctgctgga cgagcttctg gccagcgatc ttacggactg tatcacgacg gagggaacat
     5461 tgcggctctc tccattaatg tcgatgagcg atgtgcggcg ggcggcgatt ttgcgtcgct
     5521 ggctggcgat gcgtaatgcg ccgatgccct ctcgcgacgc gctggaacgt atctggcagg
     5581 aggtggcgct ggcgcgcgac gatgcctctc cctgtttacg ctttggcgat cacgagattc
     5641 gccgttatca gtcgcaactg tggtggatta aaaccgtagc cggacaacac gaaacgacgg
     5701 tcgcctggcc cgtctggcaa acaccgctgg cgctgcctgc cggcttaggg acggtacagc
     5761 tcgttcctgg cggcgaactg cgccgaccgc gagaggaaga atccgtcagc attcggttta
     5821 aagcgccagg gttgctacac attgtgggac gtcacggcgg acgtaaatta aagaaaatct
     5881 ggcaggagca ggggatcccg ccctggcgac gagacaccac gccgctgttg ttttacggcg
     5941 aaacgctgat tgcggctgcg ggtgtttttg tgacgcgtga gggagcagca gaagataaag
     6001 aaggggtgag tctggtttgg catgcctgat ggcgctgcgc ttatcaggcc tacgtatcgc
     6061 atggaacgta ggccggataa ggtgcttgca ccaccatccg gcaacaaaat actcaggatt
     6121 cgctaactac cacggtacca atttccgggt ggctgaaact ggcgatttta tcgagacgaa
     6181 gttcacaaga ctcgccggaa acctcggcaa gcagatactc tacgttttta cgtaagatca
     6241 aatcgttcgc ttttgcctgc aaaacctcgc catcttttaa cgttagcgtc agtattaaat
     6301 gatgcatgca ggcaagctca agactatcgt agtcatcgca attaatgggt tgatacgttt
     6361 cattcattga cataatcgct caccagtaag ttcgcggcag cataagctgc cttttccctg
     6421 accgactctg aaagggcgct atctgccgcc acttcattaa gcactttcaa tacacaaccc
     6481 agcgcatccg ggacataccc taagtctccg ctggcgattt ccgcataccg cttgcgtact
     6541 aactcacaat atttttccac atgccctcct gtcagcattc tgacttaacc gtggatgcaa
     6601 gtctaagcct acgaagttaa atcttgttta gcaaggtgac tataccatac tcatttgcgc
     6661 aatatcagcg cctgacgcga gtgggtaaaa gattcgttaa cagcctttta gcgcggtttt
     6721 cgctacaatg ggcgcctgat tcgaaaggag ttttctcatg gcgcttaaag cgacaattta
     6781 taaagccgtc gtcaatgtgg ctgaccttga tcgcaaccgg tttctggatg cggcattgac
     6841 gctggcgcgt cacccttctg aaacgcagga gcgcatgatg ctgcgcctgt tggcatggat
     6901 aaaatatgct gatgaacggt tgcagtttac acgcgggctc agcgcggaag atgagccgga
     6961 ggcctggctg cgcaacgatc atctgggcat cgatctctgg atagagctgg ggctgccgga
     7021 tgagcgccgt attaagaaag cctgtactca ggcgagcgac gtcgcgctct ttgcttataa
     7081 ctcccgggcg gcgcaaatct ggtggcagca gcatcaaagc aagtgcgcgc agttcgctaa
     7141 cctgtccgtc tggtatctgg atgacgggca gctggcgcag ctcagtgaat ttgccgatcg
     7201 taccatgacg ctacaggcga cgattcagga cggcgcaatc tggctttctg atgctcggaa
     7261 taatctggaa atacagctaa ccgcctggca acagccctca tgattgccat ctcccggacg
     7321 gtctccatag ccgataatga gctggaaatt acggccattc gcgcgcaggg cgcgggtggt
     7381 cagcacgtaa ataagacctc tagcgcgatt catttgcgct ttgacattcg ggcctctggc
     7441 ctgccagagt attataaaca gcgtttgctg acggccagcc accatctgat aagcgatgat
     7501 ggcgtcatta tcattaaggc gcaggagttc cggagccagg agctcaaccg ggaagcggct
     7561 atcgccaggc tggttgccgt cataaaagaa ttaaccgcgg agcagaaaag ccgtcgcgca
     7621 acccgtccga cgcgtgcctc gaaagagcgc cgcttgtcct caaaggcgca aaaatcttct
     7681 gtaaaggcgc ttcgcggcaa aattcgtcgt ccactggatt gacgggcagg aatagcaatt
     7741 tcataaggat tttatggtga gaacagcaat attgtcagta gcggcagcct gtacgctatt
     7801 tgcattgata gggtgtaata accgtgcgga agttgacgcc ctgcaacctg cgcaggcggc
     7861 ggaattaaaa cccatgcagc aaagctggcg cggcgtgctg ccctgtgcgg attgtgaagg
     7921 tattgaaacg tcactgtttc tggaaaaaga cggcacatgg gtgatgaacg agcgctatca
     7981 gggcgtgcgc gaagaacctt cctcttttgc gtcatacggt acctgggcgc ggacggcgga
     8041 taaactggtg ttaaccgaca gcaatggcga gaaatcgtat tatcgcgcga aaggcaatgc
     8101 gctggagatg ctcgacagag aaggcaatcc ggtggcttcg cagcttaatt atacgctggt
     8161 gcctgttacc gccagcctgc cggtaacgcc aatgccgctg cgtggtatgt atgtatacag
     8221 ggccgatgcg gcgaccttta ccgattgcgc gaccggaaaa cggctgccgg tcgccagtaa
     8281 cgcccagctt gagcgcggct atctggcggc gaaaggtgaa gcggaaaaac cggtgctgct
     8341 gacggtcgaa gggcattttg tgtttgccgc gaatccggac acgggcgagc cggtaaaaac
     8401 gctaatagct gataaaaatg tgaagtttgc gccgggtaaa gattgcactc a
//
LOCUS       DAJVBX010000195         8451 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.195, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000195 DAJVBX010000000
VERSION     DAJVBX010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 8451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8451
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.195"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(168..434)
                     /locus_tag="OPV72_003775"
     CDS             complement(168..434)
                     /locus_tag="OPV72_003775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DksA/TraR family C4-type zinc finger protein"
                     /protein_id="HCR9915958.1"
                     /translation="MASGWANDDAVNEQINNTIEDAVARARGELPHGESRDECESCGD
                     PIPEARRKAVPGVRLCISCQQEKDLHNATFSGYNRRGSKDSQLR"
     gene            639..1560
                     /gene="rlmF"
                     /locus_tag="OPV72_003776"
                     /pseudo
     CDS             639..1560
                     /gene="rlmF"
                     /locus_tag="OPV72_003776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459803.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(1618)-N(6))-methyltransferase
                     RlmF"
     gene            complement(1557..3779)
                     /gene="ybiO"
                     /locus_tag="OPV72_003777"
     CDS             complement(1557..3779)
                     /gene="ybiO"
                     /locus_tag="OPV72_003777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive channel protein"
                     /protein_id="HCR9915959.1"
                     /translation="MRWTLFILFCLLGAPAHAVAIPGVTTGTSTSQQAAPEPSPEQKK
                     AAYAALADVLENEASRNELIAQLREASTTPPTEPAPALAPPAAKDEKTVLENVTTVTR
                     QYGDAFATRFAQLYRNITDAPYKPFNSQTFTNALTHFLFLAVAVFGFYSVIRLCALPL
                     YRKMGLWARKKNRERSNWLQLPAMIAGAFIIDLLLLALTLFIGQMLSDNFHAGSRTIA
                     FQQSLFLNAFALIEFFKAILRLIFCPNVPELRPFAIQDATARYWNRRMSSLSSLIGYG
                     LIVAVPIISNQVNVQVGAMANVAIMLCITIWALYLIFKNKAEITQHLLSLAERSLAFF
                     SLFIRAFALVWHWLASAYFIVLFFFSLFDPGNSLKFMMGATVRSLAIIGIAAFISGMF
                     TRWIAKTITLSPHTQRNYPELQKRLNGWLSSALKVARFLTVCVAVMLLLNAWGLFDFW
                     HWLHYGAGEKMVDILIRIALILFFSAVGWTILASLIENRLASDIHSRPLPSARTRTLL
                     TLFRNALAVIISTITIMIVLSEIGVNIAPLLAGAGALGLAISFGSQTLVKDIITGVFI
                     QFENGMNTGDLVTIGPLMGTVERMSIRSVGVRQDTGAYHIIPWSSITTFANFVRGIGS
                     VVANYDVDRHEDADKANQALKDAVTALMETEDIRGLIIGEPTFAGIVGLTNTAFTLRV
                     SFTTLPLKQWTVRFALDSQVKKHFDLANVRAPVQTYQVLPAPAGGPPPDSLPPREPTI
                     "
     gene            complement(3898..4620)
                     /gene="glnQ"
                     /locus_tag="OPV72_003778"
     CDS             complement(3898..4620)
                     /gene="glnQ"
                     /locus_tag="OPV72_003778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine ABC transporter ATP-binding protein
                     GlnQ"
                     /protein_id="HCR9915960.1"
                     /translation="MIEFKNVSKHFGPTQVLHNIDLNIRQGEVVVIIGPSGSGKSTLL
                     RCINKLEEITSGDLIVDGLKVNDPKVDERLIRQEAGMVFQQFYLFPHLTALENVMFGP
                     LRVRGVKKEEAEKQAKALLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKMMLF
                     DEPTSALDPELRHEVLKVMQDLAEEGMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDG
                     SPQALIENPPSPRLQEFLQHVS"
     gene            complement(4617..5276)
                     /gene="glnP"
                     /locus_tag="OPV72_003779"
     CDS             complement(4617..5276)
                     /gene="glnP"
                     /locus_tag="OPV72_003779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015367581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine ABC transporter permease GlnP"
                     /protein_id="HCR9915961.1"
                     /translation="MQFDWSAIWPAIPLLLEGAKMTLWISVLGLAGGLVIGLAAGFAR
                     TFGGWFANHIALVFIEIIRGTPIVVQVMFIYFALPMAFNDLRIDPFSAAVVTIMINSG
                     AYIAEITRGAVLSIHKGFREAGLALGLSRRETIRHVILPLALRRMLPPLGNQWIISIK
                     DTSLFIVIGVAELTRQGQEIIAGNFRALEIWSAVAVFYLIITLVLSFILRRLERRMKI
                     L"
     gene            complement(5422..6168)
                     /gene="glnH"
                     /locus_tag="OPV72_003780"
     CDS             complement(5422..6168)
                     /gene="glnH"
                     /locus_tag="OPV72_003780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine ABC transporter substrate-binding
                     protein GlnH"
                     /protein_id="HCR9915962.1"
                     /translation="MKSLLKVSLAALTLAFAVSSHAADKKLVVATDTAFVPFEFKQGD
                     KYVGFDVDLWDAIAKELKLDYTLKPMDFSGIIPALQTKNIDLALAGITITDERKKAID
                     FSDGYYKSGLLVMVKANNNDIKSVKDLDGKVVAVKSGTGSVDYAKANIKTKDLRQFPN
                     IDNAYMELGTNRADAVLHDTPNILYFIKTAGNGQFKAVGESLEAQQYGVAFPKGSDEL
                     REKVNGALKTLRENGTYNEIYKKWFGTEPK"
     gene            complement(6645..7148)
                     /gene="dps"
                     /locus_tag="OPV72_003781"
                     /gene_synonym="pexB"
     CDS             complement(6645..7148)
                     /gene="dps"
                     /locus_tag="OPV72_003781"
                     /gene_synonym="pexB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001730644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein Dps"
                     /protein_id="HCR9915963.1"
                     /translation="MSTAKLVKTKASNLLYTRNDVSESDKKATVELLNRQVIQFIDLS
                     LITKQAHWNMRGANFIAVHEMLDGFRTALTDHLDTMAERAVQLGGVALGTTQVINSKT
                     PLKSYPLDIHNVQDHLKELADRYAVVANDVRKAIGEAKDEDTADIFTAASRDLDKFLW
                     FIESNIE"
     gene            complement(7451..8338)
                     /gene="rhtA"
                     /locus_tag="OPV72_003782"
     CDS             complement(7451..8338)
                     /gene="rhtA"
                     /locus_tag="OPV72_003782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/homoserine exporter RhtA"
                     /protein_id="HCR9915964.1"
                     /translation="MPGSTRKLPVWLPILVLLIAMSSIQSGASLAKSLFPLVGAPGVT
                     ALRLALGTLILIAFFKPWRLRFAKEQRLPLLFYGLSLGGMNYLFYLSIQTVPLGIAVA
                     LEFTGPLAVALFSSRRPVDFIWVVLAVLGLWFLLPLGQDMSHVDLTGAALALGAGACW
                     AVYILTGQRAGAEHGPATVAVGSLITAIIFVPIGAVQAGDALWHWSILPLGLAVAVLS
                     TALPYSLEMIALTRLPTRTFGTLMSMEPVLAAISGMIFLGETLTGIQILALCAIIAAS
                     MGSTLTIRREPQIKQVDVK"
BASE COUNT         2172 a         2103 c         2210 g         1966 t
ORIGIN      
        1 tgaatgacaa ataacctatt gattattaat taattcaacg gtggaattta ccgttcttgt
       61 catctggctt tacagagtcg aggttaacgg cacattctgc gacgcagaac gctaaaaagc
      121 atgagcgtaa aggaatggat gatactggcg gtttcggtaa agaaaagtca gcgtaactga
      181 ctgtcttttg aacctctacg attatatcct gaaaatgttg cgttatgtaa atctttctcc
      241 tgttggcagg atatgcataa ccgaacgccc ggtacggctt tacgccgcgc ttcagggata
      301 ggatcgccgc aagattcgca ttcatcgcga ctttcgccgt ggggaagttc gccgcgagcg
      361 cgggcaacgg catcttcaat ggtattgttg atttgttcat tcactgcgtc gtcatttgcc
      421 cagccggatg ccatcacgct ctcctgattt tagggtacct gaggttaagt gtagcgccgt
      481 caggtgaaaa aatcgcatcg cgcgatcttt tcagaccatg agcagagcca atgtcattca
      541 gagagccgat aaaacgagcg aggcagggaa ttcgcggtgg tatatttacc ccgtggcgtt
      601 atacgggtat cttacgccgc tgctaaaagg agaatgccat gtccgcccag aaaccggggt
      661 tacacccgcg caaccgccat caacaccgtt atgatctcgc cgcactgtgt cagaccacgc
      721 cggaattgac gtccttatct tatccgcacg cccgccggtg aacagagcgt tgattttgct
      781 aatccgcaag cggtaaaagc gctcaataag gcgttgttgg cgcattttta tgccgttaca
      841 cactgggaca ttccgccagg gtttttatgt ccgccagtgc ctggtcgtgc ggattatatc
      901 catcatctgg cggatctgct tggcgaaaca acagggagta ttccggcgca ggcaactatt
      961 ctggacgtgg gcgccaattg tatttatccg cttatcggcg tccatgaata tggctggcga
     1021 tttaccggta gtgaagtcag cgacgcagcg atgtccagcg cgcaggctat cattcaggct
     1081 aatacggggt taagccgcgc cattcgtctg cgtcggcaaa aagatccggc ggccattttt
     1141 accggtatta ttcataaaaa tgaattttat gacgcaacgc tttgtaaccc gccttttcac
     1201 gactccgccg ccgcagcccg cgcgggcagc gagcgtaagc gccgcaattt ggggcagaat
     1261 aaagatgatg cgctgaactt tggcggtcaa cagcaggagc tatggtgcga aggcggcgaa
     1321 gtcgccttta ttaaaaaaat gattgctgaa agccaaacct tccgccgtca ggtgttgtgg
     1381 tttacgacgt tggtgtcgcg cggcgagaat ttaccaccgc tttaccgggc gttgacggag
     1441 gctggcgcgg tgaaagtggt gaaaaaagag atggcccagg ggcaaaagca aagccgcttt
     1501 atcgcctgga cctttatgga tgacgaccag cgtcgccgtt ttatcacccg taaacgctaa
     1561 atcgtcggtt cgcgcggcgg cagtgaatca ggcggcgggc cgccggcggg ggcgggcaga
     1621 acctgatacg tttgcaccgg cgcgcgaaca ttggccagat caaaatgctt tttcacctgg
     1681 ctatcaaggg caaaacgcac cgtccactgc ttgagcggta gcgtggtgaa cgacacgcgt
     1741 aaagtaaacg ccgtgttcgt taaaccgaca ataccggcga acgtgggttc gccgataatc
     1801 agcccgcgaa tatcctccgt ctccatcagc gccgttaccg cgtctttcag cgcctgattc
     1861 gctttatccg catcctcatg gcgatccacg tcatagttgg cgacaacaga gccgataccg
     1921 cgcacaaagt tggcgaaagt ggtgatcgag gaccacggga taatatggta tgccccggta
     1981 tcctgccgca cgccgacgga acgaatcgac attctttcga ccgtccccat cagcgggcct
     2041 atggtgacta agtcgccggt attcatcccg ttttcaaact gaataaaaac gccggtaata
     2101 atatctttca ccagggtttg cgaaccgaaa gagatagcca gacctaacgc ccccgcgcca
     2161 gccagcaacg gcgcgatatt gacgccgatt tccgataaca cgatcatgat ggttatggta
     2221 ctgataatca ctgccagcgc attgcggaac agcgtcagca gcgtgcgcgt gcgggcgctg
     2281 ggtagcgggc gactatgaat atcggaggcc aggcgattct caatcagact ggcgagaatc
     2341 gtccatccca cggcggagaa gaataagatt aacgcgatac ggatgaggat atcgaccatc
     2401 ttttcccccg cgccataatg tagccagtgc cagaaatcga atagccccca ggcgttgagc
     2461 aacagcataa cggcgacgca gacggtcaaa aagcgtgcga cttttagcgc cgaggagagc
     2521 cagccgttaa gccgcttttg taattccggg taattgcgct gcgtatgggg cgacagggtg
     2581 atggttttcg ctatccagcg ggtaaacata ccggagataa acgcggcgat gccaataatc
     2641 gccagactgc gcacggtcgc gcccatcata aacttcaggc tattgcctgg gtcgaataac
     2701 gagaagaaaa acagcacgat aaagtaagcg ctggccagcc agtgccacac cagcgcaaag
     2761 gcgcggataa acaggctaaa aaaggctaat gatcgttccg ccagacttaa taaatgttgc
     2821 gtaatctccg ctttgttttt aaagatcagg tacagcgccc agatggtgat gcagagcatg
     2881 atcgccacgt tcgccatcgc cccgacctga acattcacct ggttggaaat aatcggaacg
     2941 gcaacaatca gcccgtagcc aatcaaactg ctaagggaac tcatacggcg attccagtaa
     3001 cgcgctgtcg catcctgaat cgcgaatggg cgtaattccg gtacattagg gcaaaaaata
     3061 agccgcagaa tcgctttaaa gaactctatc agcgcgaagg cattcaggaa caggctttgc
     3121 tgaaaagcga tagttcgact tccggcatgg aaattatcac tgagcatctg accgataaat
     3181 aaggtgagcg ccagtagcag caggtcgata ataaacgcgc cggcgatcat cgccgggagc
     3241 tgtaaccagt tgctgcgttc acggtttttc ttgcgcgccc acaggcccat ttttcgatat
     3301 aacggcaggg cgcaaagccg tatcacgcta taaaaaccaa ataccgcgac ggccagaaat
     3361 aaaaagtggg ttaacgcgtt ggtgaaggtt tgcgagttaa acggcttgta cggcgcatcg
     3421 gtgatgttgc gataaagctg ggcgaaacgg gtagcgaaag catcgccgta ctgacgggta
     3481 acggtggtga cgttctccag taccgttttc tcatctttgg ccgcaggcgg ggcaagcgct
     3541 ggcgctggct cggtcggcgg cgtggttgag gcttcgcgga gttgcgctat caattcgtta
     3601 cgtgaagcct cgttctccag tacgtcagcc agggccgcat aggccgcttt tttttgttca
     3661 ggactgggct ctggcgctgc ttgctggctg gttgatgtcc ccgtggtcac gccgggtatg
     3721 gcgaccgcat gggcaggcgc gcccagtaga caaaaaagga tgaacagggt ccaccgcatg
     3781 actcctccag tgagaaaaga gacgcaaaac actaagtata gatggcgcag gggagggaaa
     3841 atgaaatggg actattccat gatgcccttc ctgccgcagg gcaggaaggg cgatatctca
     3901 ggagacgtgc tgtaaaaatt cctgtaaacg tgggcttggc gggttttcga tcaacgcctg
     3961 cggactgcca tcttcggcaa tacggccttt atcgatgaaa atcagccgtg aggcgacttt
     4021 ttcggcaaag ccgatttcgt gagtgacaat gaccatggtc atgccttctt ccgccagatc
     4081 ctgcatgact ttcagcactt catggcgcag ttcagggtcc agagcggagg ttggctcgtc
     4141 aaagagcatc attttcggct tcacggccag cgctcgggca atggcgacgc gctgttgttg
     4201 acctccggaa agctcggagg ggtagtggtg cgcccgttcc gccagtccaa ctttcgctaa
     4261 cagagctttc gcctgttttt ccgcttcttc tttctttacg ccgcgcacgc gcagaggacc
     4321 gaacatcacg ttttcgagcg cggtcagatg cgggaacaga taaaactgtt gaaacaccat
     4381 gccggcttcc tggcgaatca gccgttcgtc tactttcgga tcgttgactt tcagaccatc
     4441 gacaatcaga tcgccggagg tgatctcttc cagtttattg atacagcgta ataacgtgga
     4501 tttacccgaa ccggaagggc cgataatcac aaccacttcg ccctgacgga tgtttaaatc
     4561 aatgttatgc agcacctggg tggggccaaa gtgcttggag acgtttttaa attcaatcac
     4621 aggattttca tccttctttc aagacgacgc aaaataaagc tcagcaccag cgtaatgatc
     4681 aaatagaaga cggccacggc gctccagatt tccagggcgc gaaagttacc ggcaataatt
     4741 tcctggccct gacgggtcag ctcggctacg ccgataacaa taaacaacga ggtgtctttg
     4801 atgctaatga tccactggtt gcccagcggc ggcagcatac ggcgcagagc aagcggtaaa
     4861 ataacatggc ggatggtttc ccggcgagaa aggcccagcg ccagacctgc ttcgcgaaaa
     4921 cctttgtgaa tggatagtac tgcgccacga gtaatttccg cgatataagc gccggagtta
     4981 atcataattg tcacgaccgc tgcgctgaac ggatcaatac gcaaatcatt aaatgccatc
     5041 ggcagggcaa agtagataaa catgacctgg acaacgatag gcgtgccgcg aataatttca
     5101 atgaaaacca gggcgatgtg gttagcgaac cagccgccaa acgtacgggc aaaacctgcc
     5161 gccagtccaa taaccaggcc gccagccaga ccgaggaccg agatccacag ggtcatttta
     5221 gcgccctcaa gcaaaagcgg aatggcgggc cagatggcgc tccagtcaaa ctgcatatgt
     5281 cgttcctgtt accgtggtgt aaatagtcaa atgctctatc cggcgcggaa atggcgtgaa
     5341 agtgtcttat ccgtcacgga aaagagctgt aggcccggtg agcgtcctca ctaccgggcc
     5401 acaagccaac atcaggtcgt tttatttagg ttctgtaccg aaccattttt tgtagatttc
     5461 gttataggtg ccattctcac gcagcgtttt cagcgcgccg ttgactttct cgcgcagttc
     5521 atcgctgcct ttcgggaagg caactccgta ttgctgtgct tccagcgatt cgcctaccgc
     5581 cttgaactgg ccgttgcctg cggttttgat aaagtacagg atgttcggcg tatcgtgcag
     5641 aacggcgtct gcgcggttgg tgcctaattc catgtacgcg ttatcaatgt tcgggaactg
     5701 acgcaggtct ttggttttga tattcgcttt cgcgtaatcc accgacccgg ttccgctctt
     5761 cacggcaacg actttgccat cgaggtcttt aacgctttta atatcgttat tgttggcttt
     5821 caccatcacg agcagaccgc ttttgtaata gccatcggaa aagtcgatcg cttttttacg
     5881 ctcgtccgta atcgtaatac ccgccagcgc cagatcgata tttttggttt gtaatgccgg
     5941 aataatgccg ctgaaatcca tcggtttcag ggtgtagtcc agcttcagtt ctttcgcgat
     6001 agcgtcccac agatcaacat caaaaccgac gtatttgtcg ccctgtttaa attcaaacgg
     6061 aacgaacgcc gtatcggttg ccacaacgag tttcttatcc gcagcgtgcg aagacaccgc
     6121 aaaagccagg gtaagtgcag ccagtgaaac ttttaataga gacttcatag catttccttt
     6181 tctatccacg gggcgatccc ctgcgagaac atgtagcgta atgaaaaaat catgccaatt
     6241 atgtaactca ttgttttaac agaagcgtca atcattcctg tgcacaataa gtcgggcaaa
     6301 accagtatgc tgcactgttt tggggcactg atttagtgca tgaataacaa agtagagata
     6361 cagggtctat ttagcgtaaa aattgttgtt aaaacaatct ttaattaacg attgtgtgat
     6421 gtaattatta caaataattc acttttatcg aagggaagta caagacatgt gcactattta
     6481 agtgcaaaac ccctgtgcca ggcaggggta tagggatgac ttatatacct gtgtacatca
     6541 agttgcaggt gcgttcgctt cagtgaccga cggaagtcag gctcctgcgg attcgctgcg
     6601 tttgtacctt cctgcaactc gaagtattca gggtagagat agatttattc gatgttggat
     6661 tcgataaacc acaggaattt atcgaggtcg cgtgatgcgg cggtaaagat atcggcagtg
     6721 tcttcatctt tggcttcacc gatagctttg cgaacatcat tagcgacaac agcgtagcga
     6781 tcggccagtt cttttaagtg atcctgcacg ttatggatgt cgagcggata gcttttcagt
     6841 ggagttttgc tgttgataac ttgcgtggtg cctaacgcca caccgccaag ctgtacggcg
     6901 cgctcggcca tagtatccag atgatcggtc agtgcggtac ggaagccatc cagcatctca
     6961 tgaacggcaa taaagttagc accgcgcatg ttccagtggg cctgtttcgt gatcagcgac
     7021 aggtcaatga actggatcac ctgacgatta agcaactcaa ccgtcgcttt tttatcgctc
     7081 tctgatacat cgttacgggt ataaagcaga ttagacgctt ttgtttttac cagtttagcg
     7141 gtactcataa tctcatatcc tcttgatgtt tgtgtcccag gtaattaacg aaaataagta
     7201 tagcaccggt ttttaacttc gcttttttga atttacctat cactttaata gtacagacaa
     7261 gatttaatat ttattttggt tatgaatcaa ttggttagat gagtttgttg tttgatgggt
     7321 aataattctc attttaatgt aaaaaatgag aaaaaatatg acaaaaaatg acgaagtaat
     7381 agcgcgataa taaaaggtga ataacgaggt gatattctgc atgattatgc acatcatgca
     7441 gaataagaaa ctattttacg tcaacttgtt taatttgcgg ttcgcggcga atcgttaggg
     7501 tagaacccat tgaggcggca atgatggcgc acagggccag gatttgtatg cccgtaagcg
     7561 tttcgcccag aaaaatcatc ccggaaatgg cggccagcac gggttccatg ctcatcagcg
     7621 taccgaaggt gcgagttggc aggcgcgtca gcgcaatcat ttccagtgaa taaggcagcg
     7681 ccgtagaaag cacagcgacc gctaacccta agggaagaat cgaccagtgc catagcgcat
     7741 cgccagcctg aactgcgcca atcggcacga aaatgatggc ggtaatcagc gagcctaccg
     7801 ccaccgtggc cggaccatgt tccgcgcctg ctcgctggcc ggtaagaata tagacagccc
     7861 aacaggcgcc agcgccgagc gctaacgcgg ccccggtaag atcgacgtga gacatatctt
     7921 gtcctaatgg cagcaggaac cagagtccaa gcacagccag tacgacccaa ataaaatcta
     7981 ccggacgccg ggatgaaaac agcgcgaccg ccagagggcc ggtaaattcc agcgcgaccg
     8041 caatacccaa cggcaccgtc tgaatcgaca gatagaatag atagttcatc ccgcccagcg
     8101 acagaccata aaacagtaaa ggcagccgct gctctttggc aaaacgcaaa cgccagggtt
     8161 tgaaaaaggc gataaggata agcgttccca acgccagacg aagcgccgtt acacccggcg
     8221 cgccaacaag aggaaataac gattttgcca gtgaagcgcc actctgaata gaggacatgg
     8281 caatgagcaa aaccaaaatg ggcaaccaga ctggtagttt acgtgttgac cccggcatcc
     8341 tttctcctgt caaaaaatgt cagtacgagt aaaggtggca gtgtaatgga aattccccgg
     8401 agcggttgag gattcgttga aaaaaaaatt tccaggattc cataaaatga a
//
LOCUS       DAJVBX010000196         8450 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.196, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000196 DAJVBX010000000
VERSION     DAJVBX010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 8450)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8450)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8450
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.196"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            127..1311
                     /gene="ompS1"
                     /locus_tag="OPV72_003783"
     CDS             127..1311
                     /gene="ompS1"
                     /locus_tag="OPV72_003783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpS1"
                     /protein_id="HCR9915965.1"
                     /translation="MNRKVLALLVPALLVAGAANAAEIYNKNGNKLDLYGKVDGLRYF
                     SDNAGDDGDQSYARIGFKGETQINDMLTGYGQWEYNIKVNTTEGEGANSWTRLGFAGL
                     KFGEYGSFDYGRNYGVIYDIEAWTDALPEFGGDTYTQTDVYMLGRTNGVATYRNTDFF
                     GLVEGLNFALQYQGNNENGGAGAGEGTGNGGNRKLARENGDGFGMSTSYDFDFGLSLG
                     AAYSSSDRSDNQVARGYGDGMNERNNYAGGETAEAWTIGAKYDAYNVYLAAMYAETRN
                     MTYYGGGNGEGNGSIANKTQNFEVVAQYQFDFGLRPSIAYLQSKGKDLGGQEVHRGNW
                     RYTDKDLVKYVDVGMTYYFNKNMSTYVDYKINLLDEDDDFYANNGIATDDIVGVGLVY
                     QF"
     gene            complement(1572..1760)
                     /locus_tag="OPV72_003784"
     CDS             complement(1572..1760)
                     /locus_tag="OPV72_003784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCR9915966.1"
                     /translation="MTNKIHFRCPCCHGSQYRTSTFDVTEQNPFGAKCIFCKSTMITF
                     DNVGLYIRSGQVPLDFRK"
     gene            complement(1771..1983)
                     /locus_tag="OPV72_003785"
     CDS             complement(1771..1983)
                     /locus_tag="OPV72_003785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCR9915967.1"
                     /translation="MTTKITGLVKWFNPEKGFGFITPKDGSKDVFVHFSAIQSNEFRT
                     LNENQEVEFSAEQGPKGPSAVNVVAL"
     gene            complement(2429..3697)
                     /locus_tag="OPV72_003786"
     CDS             complement(2429..3697)
                     /locus_tag="OPV72_003786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HCR9915968.1"
                     /translation="MFALCDVNSFYASCETVFRPDLCGRPVVVLSNNDGCVIACSAEA
                     KQLGIAAGEPYFKQKERFRRSGVVCFSSNYELYADMSNQVMTTLEEMVPRVEIYSIDE
                     AFCDLTGVRNCRDLTDFGHEIRATVLKRTHLTVGVGIAQTKTLAKLANHAAKKWQRQT
                     DGVVDLSNIDRQRRLLALIPVEDVWGVGRRISKKLNALGIKTALDLSEQSTWIIRKHF
                     NVVLERTVRELRGEPCLELEEFAPAKQEIVCSRSFGERVTDYEEMRQAVYSYAARAAE
                     KLRGEHQYCCFISTFVKTSPFALNEPYYGNSAAVTLLTPTQDSRDIINAAVKCLDKIW
                     RDGHRYQKAGVMLGGFFSQGVAQLNLFDDNAPRAGSAKLMEVLDHLNAKDGKGTLYFA
                     GQGMSQQWAMKREMLSPRYTTRYSDLLRVK"
     gene            complement(3700..4119)
                     /locus_tag="OPV72_003787"
     CDS             complement(3700..4119)
                     /locus_tag="OPV72_003787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translesion error-prone DNA polymerase V
                     autoproteolytic subunit"
                     /protein_id="HCR9915969.1"
                     /translation="MEFFRPTELREIIPLPFFSYLVPCGFPSPAADYIEQRIDLNELL
                     VSHPSSTYFVKATGDSMIEAGISDGDLLVVDSSRNADHGDIVIAAIEGEFTVKRLQLR
                     PTVQLIPMNGAYRPIPVGSEDTLDIFGVVTFIIKAVS"
     gene            complement(4246..4407)
                     /locus_tag="OPV72_003788"
     CDS             complement(4246..4407)
                     /locus_tag="OPV72_003788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001532308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915970.1"
                     /translation="MGAGQKINCCQGNALARGDNLRCGTVDAVQKIWPPDWLKYAHMT
                     IQPENLQNA"
     gene            complement(4710..4799)
                     /locus_tag="OPV72_003789"
     tRNA            complement(4710..4799)
                     /locus_tag="OPV72_003789"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(4763..4765),aa:Ser,seq:cga)
     gene            4888..5685
                     /gene="mtfA"
                     /locus_tag="OPV72_003790"
     CDS             4888..5685
                     /gene="mtfA"
                     /locus_tag="OPV72_003790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgsA anti-repressor MtfA"
                     /protein_id="HCR9915971.1"
                     /translation="MIKWPWKAQEITQNEDWPWDDALAIPLLVNLTAQEQARLIALAE
                     RFLQQKRLVALQGFELDSLKSARIALIFCLPILELGIEWLDGFHEVLIYPAPFVVDDE
                     WEDDIGLVHSQRVVQSGQSWQQGPIILNWLDTQDSFDASGFNLIIHEVAHKLDMRNGD
                     RASGIPFIPLRDVAGWEHDLHAAMNNIQDEIDLVGESAASIDAYAATDPAECFAVLSE
                     YFFSAPELFAPRFPALWQRFCQFYRQDPSQRLRVSAAEGDYGEESEH"
     gene            5786..5861
                     /locus_tag="OPV72_003791"
     tRNA            5786..5861
                     /locus_tag="OPV72_003791"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5819..5821,aa:Asn,seq:gtt)
     gene            6409..6484
                     /locus_tag="OPV72_003792"
     tRNA            6409..6484
                     /locus_tag="OPV72_003792"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6442..6444,aa:Asn,seq:gtt)
     gene            6665..7939
                     /locus_tag="OPV72_003793"
     CDS             6665..7939
                     /locus_tag="OPV72_003793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001751368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase arm-type DNA-binding domain-containing
                     protein"
                     /protein_id="HCR9915972.1"
                     /translation="MSLTDIKAKNAKPLEKEYKLTDGFGMFLRVTPKGSKYWQMAYRF
                     EGKQKLFSIGVYPAVSLSDARQRRDEARRLLAQGIDPNAKKQAEVKELKAKRDNTRSF
                     RTVAKAWFSTKTKWSDDYGDAVWKRLETYVFPVIGDKDVAELDTGDLLVPVKKVEALG
                     YLEVAMRIQQYITAILRHAVQQKLIRHNPAYDMEGAVQKPQTEHRPALELEEIPQLLN
                     KIAEYKGRRLTILAIQLNLMIFIRSSELRFARWSEIDFKSKLWVIPEQREAIENVKHS
                     TRGAKMKRKHLVPLCKQAMKILKEIRQLTYEEGHDDGLIFTGCYDSFKPMSENTINKA
                     LRNMGYDTKQDICGHGFRTLACSALIESGLWSEDAVELQMSHKESNSVRAAYTHKAKH
                     LDQRRLMLQWWADFLDANSNDMVRPFEFDSNK"
     gene            complement(7986..>8450)
                     /locus_tag="OPV72_003794"
     CDS             complement(7986..>8450)
                     /locus_tag="OPV72_003794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020803150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpnT protein"
                     /protein_id="HCR9915973.1"
                     /translation="LDLFSGIAKKKGFPFVILFLSGTDSYGKLDSEVMNASENEIAEM
                     MSLLRGSFVRTLSSELYRHGYACSATLLRRVLAEDSISRSQSKYYTYAASDMKKSIDY
                     SKDIAWTEKIPSTEEYLKSLFIEHKRKYALWEIMLEKIAGLAIEKDSVSYSA"
BASE COUNT         2234 a         2017 c         1962 g         2237 t
ORIGIN      
        1 atattttaaa tatctttgtt acatgttatt ttttaaattc catgaacttc atagaatagt
       61 atcaatttgt agttttgttg aagtggctac atattcatat aaattattat cataagggaa
      121 tacataatga acagaaaagt tctggcactg cttgtcccgg cgttattagt ggcaggcgca
      181 gcaaatgcgg ctgaaattta taataaaaat ggcaacaaac tcgacctgta cggcaaagtt
      241 gatggtctgc gttacttctc tgacaatgca ggcgacgatg gcgatcagtc ctacgcccgt
      301 attggcttta aaggcgaaac gcagatcaac gatatgctga ccggctatgg tcagtgggaa
      361 tacaacatta aggtgaacac caccgaaggc gaaggtgcaa actcctggac tcgtctgggc
      421 tttgccggtc tgaaattcgg cgagtacggc tctttcgatt atggccgtaa ctatggtgtt
      481 atctacgaca ttgaagcctg gaccgatgcg ctgccggaat tcggcggtga tacttatacc
      541 cagaccgatg tctatatgct gggcagaacc aacggcgttg ccacctaccg taataccgac
      601 ttcttcggtc tggtggaagg cctgaacttc gcgttgcagt accagggtaa taatgaaaac
      661 ggcggtgctg gtgctggtga aggtacaggt aacggcggca accgcaaact ggcccgtgaa
      721 aacggcgacg gtttcggtat gtctacctcc tacgactttg acttcgggtt aagcctgggt
      781 gcggcctact cttcctctga ccgttcggac aatcaggttg ctcgtggtta tggcgacggc
      841 atgaatgagc gcaacaacta tgccggcggt gaaaccgctg aagcctggac cataggtgcc
      901 aaatatgacg cctacaatgt ttacctggcg gccatgtacg ctgaaacccg caacatgacc
      961 tattatggcg gcggcaatgg cgaaggtaat ggcagtattg ctaacaaaac ccagaacttt
     1021 gaagtggttg cgcagtacca gttcgatttc ggtctgcgtc cgtccatcgc ctacttgcag
     1081 tctaagggca aagatttagg cggtcaggaa gtccatcgtg gcaactggcg ttacaccgac
     1141 aaagatctgg ttaaatatgt tgacgtcggt atgacttact acttcaacaa aaatatgtcc
     1201 acctacgttg attataaaat caacctgctg gacgaagatg atgacttcta cgcaaacaac
     1261 ggtattgcaa ccgatgatat cgtaggtgtt ggtctggtct accagttcta agacgcttta
     1321 tgttattcaa gcccgtgctt agcgcgggct tgttattata gggcaagaat taaataacgg
     1381 ataacggcgc aaagacaggt gaccaggctt catcggatag atgaagacaa cgtcgctctt
     1441 ttcaggcgct gtctgcaaga gaaataacac ctttggggaa aggtaaatgc cactatagat
     1501 gatggatgtc agcgtctata gatgataatc atccgggcat aaaaaaagct cctgtacgga
     1561 gctaatatga attattttct aaaatctagc ggaacctgtc ctgagcgaat gtataatcca
     1621 acattatcaa aagtgatcat ggttgactta caaaaaatac atttcgcgcc aaacgggttt
     1681 tgctcagtaa catcgaatgt cgatgttctg tattgtgaac catggcaaca tggacaccgg
     1741 aagtgaattt tattagtaat atcagttgcc ttaaagcgcc acaacgttga ccgctgatgg
     1801 accttttggt ccctgctctg ctgaaaactc cacttcctga ttttcattca gagtgcggaa
     1861 ttcattactt tgaatggcgg aaaaatgcac aaacacatct ttgctgccat ctttaggcgt
     1921 aatgaaacca aagccctttt cagggttaaa ccattttact aaaccagtga ttttcgtcgt
     1981 cataatattg ttaccttttg aatgagccct tgggcgaaat ggcctgaaga aaattatcag
     2041 agagaaaaaa acctaaagga gatctcaaga ggaacaaatg atgagaaata ttacaatcac
     2101 tacttcagat aagtttgtat caaaccgcac aaccattaac gcatggttaa ctgaacatag
     2161 caagctttag ttttgttaaa aaaatattaa ttgtttttta gcattatcac gctgattgcc
     2221 atactctttt tatccatgcc catcgctacg gctgaaacca ggcgtaaata agttacgtct
     2281 cacaacgcct gcctggcaat aaacgcgcca catttcctga tgtcgtaaac caggatacat
     2341 gcgcattatc gtgagaggtt cctgtgatct tgtgcgacca aaagaacggg gacgatttag
     2401 caactatctc aggcattgat cgcacaagtt acttaacacg cagtagatca gagtatcttg
     2461 tggtgtaccg aggcgaaagc atttctcgct tcatagccca ctgttgcgac atcccctgcc
     2521 cggcgaagta cagcgtcccc ttcccgtctt ttgcgttaag atggtccagt acttccatca
     2581 acttcgcact accggcgcgc ggcgcgttat cgtcgaaaag gttgagttgc gctacgccct
     2641 ggctgaagaa gccacccagc atcacccccg ctttctggta gcgatggccg tcgcgccaga
     2701 ttttatccag acatttcaca gccgcattga taatgtcacg tgaatcctgc gtgggggtga
     2761 gaagcgtcac cgcggcgctg ttaccgtagt agggctcgtt cagggcaaag ggtgatgttt
     2821 tgacgaatgt tgaaatgaaa cagcagtact ggtgctcgcc gcggagtttt tctgccgcgc
     2881 gcgcagcgta gctgtaaaca gcctggcgca tttcctcata gtctgtgacc cgctcgccga
     2941 aagagcggct acaaacgatt tcctgctttg ccggcgcaaa ctcttcaagc tccagacatg
     3001 gctctccgcg aagctctctc acggtacgct ccagcacgac attgaagtgt ttcctgatga
     3061 tccaggtact ttgttcagag agatcgagag cagtcttgat gcccagggca ttgagcttct
     3121 tactgatgcg tctgccgaca ccccagacat cctctacggg tatcagggcc agcagccgac
     3181 gctggcgatc gatgttcgac aggtcaacca ccccgtcggt ctggcgctgc cactttttcg
     3241 cagcatggtt agccagcttg gcaagggttt tcgtctgggc aatgcctaca ccgacagtca
     3301 ggtgcgtgcg cttcaggacc gtcgctctta tctcgtgccc gaaatctgtc agatcccggc
     3361 agtttcgtac ccccgtcaga tcacaaaaag cctcatcaat gctgtaaatt tctacccgcg
     3421 gcaccatctc ctctagtgtg gtcattacct ggttcgacat atcagcgtaa agctcgtaat
     3481 tactgctgaa gcaaacaaca ccggatcgcc ggaagcgttc tttctgtttg aagtatggct
     3541 cacctgctgc gataccgagt tgtttcgcct cggcgctaca cgcgataacg cagccatcat
     3601 tgtttgataa caccaccacc ggtcggccac ataaatcagg acgaaagacc gtttcgcagg
     3661 aggcgtaaaa gctattaaca tcgcagagcg cgaacataat caactgaccg ctttaatgat
     3721 aaaggtcacc accccgaata tgtcgagcgt gtcttcactg ccgacaggta tgggtcgata
     3781 ggcgccgttc atggggatta actgcactgt cggacgcaac tgcaaccgct ttacggtgaa
     3841 ctctccttca attgccgcaa ttacaatgtc accgtggtca gcgttccgtg agctatccac
     3901 caccagcagg tcaccgtcgc tgatgcctgc ttcaatcatt gaatcccccg ttgctttgac
     3961 aaaatatgtt gagctgggat gagaaacgag caactcatta agatcgatac gctgctcaat
     4021 atagtccgcc gcggggctgg ggaatccaca cggcactaag taactgaaaa atgggagagg
     4081 aataatttcg cgcaactctg taggtctgaa aaattccata atccatacct cgaatactgt
     4141 ttttatatac agtagtgtta tttgaacatg cgcgcaagat accggagtcg ctacgactgt
     4201 ttaaatcttc gtcgcttcgt ttgtaagttt ctctctcagt tcaaattatg cgttttgtaa
     4261 attttccggt tgtattgtca tgtgtgcata tttaagccag tctggaggcc agattttctg
     4321 tacagcgtcg acagtcccgc agcgtaagtt atcgccacgc gccagcgcgt ttccctgaca
     4381 gcaattaatc ttctgcccgg cgcccatgtc tacaggggaa catttcgggc aacaggccgg
     4441 gtgcgacgat taccgaggac gacggcgtta agtcgccgca agtgacatca ctgtgaatcc
     4501 cgatggggta cagcgaaata gcggggcaga aaaccaggag ttgacttatg atcgaaaagt
     4561 aaaaataaca ccatccctgg ccccctcttc tggcagaaaa agcataagat ggcgatacgt
     4621 ttttcacgta atattctaac agaatactct aagtgtattc taagtgtgag actgatcgct
     4681 gaaagaagat gagctaagtg tttgaattgt ggcggagaga gggggatttg aacccccggt
     4741 agagttgccc ctactccggt tttcgagacc ggtccgttca gccgctccgg catctctccg
     4801 tatattgcaa tgatgccagg taatttggca ttttaacaga ccctattcgg gtaattttgt
     4861 tcaagtgacg agtttacgag caaaacgatg attaagtggc cctggaaagc acaagaaata
     4921 acccagaacg aagactggcc gtgggatgat gcgctggcta tacctcttct ggtaaacctc
     4981 accgcgcaag aacaggctcg gcttattgcg ctagccgaac gttttttgca gcagaaaaga
     5041 ctggtagcgc tacagggatt tgagctcgac tcgttaaaaa gtgcacgtat tgcgttaatt
     5101 ttttgcttac cgatcctgga gctcggtatt gagtggcttg atggttttca tgaagtgctc
     5161 atttatcccg cgccctttgt ggtagatgat gaatgggaag atgacatagg tctggtgcac
     5221 agccagcgtg tcgtacagtc ggggcaaagc tggcaacaag ggcccatcat tctgaactgg
     5281 ctggataccc aggactcgtt cgatgcttcg ggtttcaacc tcattattca tgaagttgcg
     5341 cacaaactgg atatgcgtaa tggcgatcgc gccagcggca tccctttcat cccgttacgc
     5401 gatgtggctg gctgggaaca cgatctccac gcggcaatga ataatattca ggatgaaatc
     5461 gatcttgttg gcgaaagcgc tgccagtata gatgcctatg ccgccaccga ccctgcagaa
     5521 tgttttgccg tgttgtcaga gtattttttc agcgcgccag aactgtttgc tccacgtttc
     5581 ccggcgctat ggcagcgttt ttgccagttc tatcgccagg atccttctca gcgcttacgg
     5641 gtaagcgctg ccgaaggcga ctacggcgag gaatccgaac attaattcct cactttgtgg
     5701 gttaattaac caattgaatt ggcgcgttaa ttttactgtt gacacgttat agccggccca
     5761 gtattcaacg cctcgttgaa acaattcctc tgtagttcag tcggtagaac ggcggactgt
     5821 taatccgtat gtcactggtt cgagtccagt cagaggagcc agatttagga aagcagacgt
     5881 tcactgacgt ctgctttctg catttatatc aactgattat ccccttcttc aagtttactc
     5941 tcgtttacta aaaaccactc gaagccatac ccttttgctg gtaaagctgg tttgccataa
     6001 ttctgcctgt gatattgacg gaaatctttt cgcctgcacc agaaatttat ctgccatttc
     6061 cgctaccggc gtcagactgc ctgtatcaac cattttcaca aaatatttca cgtctaaagt
     6121 tcattctgcc ccctgccctt aatctctacg gcgttatgtc tcagaattat ttgccaagtg
     6181 cctgccaatt tttcacgcct catcaggcgc tggtacatag ccattgcggt aaggtcacag
     6241 catttgactt gtgcaatgac agacaaagtt gcgccatgcc ggggcaaagt aggaattaga
     6301 tcaaaacttc aacgctttgt tgtttttgtc agcaaacaaa cgcgcaatct tatttccccc
     6361 tttgacaagc cgatcgcaca tcgttactat gcgccccgtt cacacgattc ctctgtagtt
     6421 cagtcggtag aacggcggac tgttaatccg tatgtcactg gttcgagtcc agtcagagga
     6481 gccattttca agaaagcaga cgttcactaa cgtctgcttt ctgcatttct atcaattggt
     6541 tatcccctct cagtcgttca ccctcgttca ctaaaaacca ctcgaagcca tatcattttg
     6601 atggtaaaaa tgctggtaat gctggttcga tttccctttt accaacaaat gagggggtgt
     6661 tttcatgtca ctgactgata ttaaagcaaa aaatgcaaaa ccccttgaga aggaatacaa
     6721 gcttactgat ggctttggta tgttccttcg tgttacccct aaaggttcga aatactggca
     6781 aatggcttac cgcttcgaag ggaaacaaaa actcttctct attggtgttt accctgctgt
     6841 ttctctttct gacgcaagac agcgccgtga tgaggccaga aggcttcttg ctcagggtat
     6901 tgaccctaat gcaaagaaac aggcagaggt taaagagctt aaagccaaac gtgataatac
     6961 acgctccttc agaacagtag ccaaagcgtg gttctccacg aaaacaaaat ggtctgatga
     7021 ttatggtgat gccgtatgga agcgccttga aacttatgtc ttcccggtaa tcggtgacaa
     7081 agatgttgcc gaactggata cgggtgatct gctggttccg gtgaaaaaag ttgaggctct
     7141 tggttatctt gaagttgcca tgcgcattca acaatacatt acggcaatcc tgcgtcatgc
     7201 cgtccagcaa aagctgatac gccataaccc agcctatgat atggaaggtg cagttcagaa
     7261 accacaaact gaacaccgcc ctgcacttga gctggaagaa ataccccagt tactgaacaa
     7321 aattgccgaa tacaaaggcc gcaggttaac catactggca atacagctca atctgatgat
     7381 tttcattcgt tccagtgagc tgcgtttcgc tcgctggtca gaaattgatt tcaaaagtaa
     7441 gttatgggtg atacccgaac agcgtgaagc gattgaaaac gtcaaacatt caactcgtgg
     7501 ggctaaaatg aagcgtaagc acttagttcc cctttgtaag caggccatga agatactcaa
     7561 agagatccga caactgactt atgaagaagg tcatgatgac ggattaatct ttactggttg
     7621 ttatgactcg tttaaaccca tgagcgaaaa caccatcaac aaagcgcttc gcaatatggg
     7681 ctatgacaca aagcaggaca tctgtggaca cggtttccgc actctggcct gtagtgcctt
     7741 aattgagtcc gggctatggt cagaagacgc tgtagagctt caaatgagcc ataaggaaag
     7801 caatagcgtc cgtgctgctt atacccacaa ggcaaaacac cttgaccagc gccgcctgat
     7861 gctccagtgg tgggctgatt tccttgatgc taacagcaac gatatggtca ggccgtttga
     7921 gtttgattca aataaataaa gggaaaggcc gttcgcggcc tttcaacttc atgcttaatt
     7981 acagtctatg ctgaatatga tactgaatct ttctctatcg ctaaaccagc gattttttcc
     8041 agcattattt cccagagtgc gtattttctt ttgtgctcaa taaacagaga ttttaaatac
     8101 tcttctgttg aagggatttt ttcagtccat gcaatatctt tactgtaatc aatgcttttt
     8161 ttcatatcag atgccgcata ggtgtagtat ttactctgag aacgactgat actgtcctct
     8221 gccagcactc tacggagcag agttgcagaa catgcataac catgcctgta aagctcactc
     8281 gataaggtac gaacaaaaga accgcgtaat aaagacatca tctctgcgat ttcattttca
     8341 ctcgcattca tgacttcaga atcaagtttt ccataactat ctgtcccgga caagaaaaga
     8401 ataacaaacg gaaagccttt tttctttgct atgccagaga acaaatccag
//
LOCUS       DAJVBX010000197         8363 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.197, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000197 DAJVBX010000000
VERSION     DAJVBX010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 8363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8363
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.197"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..687)
                     /gene="ssaT"
                     /locus_tag="OPV72_003795"
     CDS             complement(<1..687)
                     /gene="ssaT"
                     /locus_tag="OPV72_003795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system apparatus
                     protein SsaT"
                     /protein_id="HCR9915974.1"
                     /translation="MTQQVNEWLIALAVAFIRPLSLSLLLPLLKSGSLGAALLRNGVL
                     MSLTFPILPIIYQQKIMMHIGKDYSWLGLVTGEVIIGFLIGFCAAVPFWAVDMAGFLL
                     DTLRGATMGTIFNSTMEAETSLFGLLFSQFLCVIFFISGGMEFILNILYESYQYLPPG
                     RTLLFDRQFLKYIQAEWRTLYQLCISFSLPAIICMVLADLALGLLNRSAQQLNVFFFS
                     MPLKSILVLLT"
     gene            complement(688..954)
                     /gene="ssas"
                     /locus_tag="OPV72_003796"
     CDS             complement(688..954)
                     /gene="ssas"
                     /locus_tag="OPV72_003796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system apparatus
                     protein SsaS"
                     /protein_id="HCR9915975.1"
                     /translation="MNDSELTQFITQLLWIVLFTSMPVVLVASVVGVIVSLVQALTQI
                     QDQTLQFMIKLLAIAITLMVSYPWLSGILLNYTRQIMLRIGEHG"
     gene            complement(951..1598)
                     /gene="ssaR"
                     /locus_tag="OPV72_003797"
     CDS             complement(951..1598)
                     /gene="ssaR"
                     /locus_tag="OPV72_003797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system export apparatus
                     protein SsaR"
                     /protein_id="HCR9915976.1"
                     /translation="MSLPDSPLQLIGILFLLSILPLIIVMGTSFLKLAVVFSILRNAL
                     GIQQVPPNIALYGFALVLSLFIMGPTLLAVKERWHPVQVAGAPFWTSEWDSKALAPYR
                     QFLQKNSEEKEANYFRNLIKRTWPEDIKRKIKPDSLLILIPAFTVSQLTQAFRIGLLI
                     YLPFLAIDLLISNILLAMGMMMVSPMTISLPFKLLIFLLAGGWDLTLAQLVQSFS"
     gene            complement(1666..2634)
                     /gene="ssaQ"
                     /locus_tag="OPV72_003798"
     CDS             complement(1666..2634)
                     /gene="ssaQ"
                     /locus_tag="OPV72_003798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system cytoplasmic ring
                     protein SsaQ"
                     /protein_id="HCR9915977.1"
                     /translation="MLRIANEERPWVEILPTQGATIGELTLSMQQYPVQQGTLFTINY
                     HNELGRVWIAEQCWQRWCEGLIGTANRSAIEPELLYGIAEWGLAPLLQASDATLCQNE
                     PPTSCSNLPHQLALHIKWTVEEHEFHSIIFTWPTGFLRNIVGELSAERQQIYPAPPVV
                     VPVYLGWCQLTLIELESIEIGMGVRIHCFGDIRLGFFAIQLPGGIYARVLLTEDNTMK
                     FDELVQDIETLLASGSPMLKSDGTSSVELEQIPQQVLFEIGRASLEIGQLRQLKTGDV
                     LPVGGCFAPEVTIRVNDRIIGQGELIACGNEFMVRITRWYLCKNTA"
     gene            complement(2615..2989)
                     /gene="ssaP"
                     /locus_tag="OPV72_003799"
     CDS             complement(2615..2989)
                     /gene="ssaP"
                     /locus_tag="OPV72_003799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system apparatus
                     protein SsaP"
                     /protein_id="HCR9915978.1"
                     /translation="MRITKVEGSLGLPCQSYQDDNEAEAERMDFEQLMHQALPIGENN
                     PPAALNKNVVFTQRYRVSGGYLDGVECEVCESGGLIQLRINVPHHEIYRSMKALKQWL
                     ESQLLHMGYIISLEIFYVKNSE"
     gene            complement(2970..3347)
                     /gene="ssaO"
                     /locus_tag="OPV72_003800"
     CDS             complement(2970..3347)
                     /gene="ssaO"
                     /locus_tag="OPV72_003800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system apparatus
                     protein SsaO"
                     /protein_id="HCR9915979.1"
                     /translation="METLLEIIARREKQLRSKLTVLDQQQQAIITEQQICQTRALAVT
                     TRLKELMGWQGTLSCHLLLDKKQQMAGLFTQAQSFLTQRQQLENQYQQLVSRRSELQK
                     NFNALMKKKEKITMVLSDAYYQS"
     gene            complement(3350..4651)
                     /gene="ssaN"
                     /locus_tag="OPV72_003801"
     CDS             complement(3350..4651)
                     /gene="ssaN"
                     /locus_tag="OPV72_003801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SctN family type III secretion system ATPase
                     SsaN"
                     /protein_id="HCR9915980.1"
                     /translation="MKNELMQRLRLKYPPPDGYCRWGRIQDVSATLLNAWLPGVFMGE
                     LCCIKPGEELAEVVGINGSKALLSPFTSTIGLHCGQQVMALRRRHQVPVGEALLGRVI
                     DGFGRPLDGCELPDVCWKDYDAMPPPAMVRQPITQPLMTGIRAIDSVATCGEGQRVGI
                     FSAPGVGKSTLLAMLCNAPDADCNVLVLIGERGREVREFIDFTLSEETRKRCVIVVAT
                     SDRPALERVRALFVATTIAEFFRDNGKRVVLLADSLTRYARAAREIALAAGETAVSGE
                     YPPGVFSALPRLLERTGMGEKGSITAFYTVLVEGDDMNEPLADEVRSLLDGHIVLSRR
                     LAERGHYPAIDVLATLSRVFPVVTSHEHRQLAAILRRRLALYQEVELLIRIGEYQRGV
                     DTDTDKAIDTYPDICTFLRQSKDEVCGPELLIEKLHQILTE"
     gene            complement(4641..6686)
                     /gene="ssaV"
                     /locus_tag="OPV72_003802"
     CDS             complement(4641..6686)
                     /gene="ssaV"
                     /locus_tag="OPV72_003802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system apparatus
                     protein SsaV"
                     /protein_id="HCR9915981.1"
                     /translation="MRSWLGEGIRAQQWLSVCAGRQDMVLATVLLIAIVMMLLPLPTW
                     MVDILITINLMFSVILLLIVIYLSDPLDLSVFPSLLLITTLYRLSLTISTSRLVLLQH
                     NAGNIVDAFGKFVVGGNLTVGLVVFTIITIVQFIVITKGIERVAEVSARFSLDGMPGK
                     QMSIDGDLRAGVIDADHARTLRQHVQQESRFLGAMDGAMKFVKGDTIAGIIVVLVNII
                     GGIIIAIVQYDMSMSEAVHTYSVLSIGDGLCGQIPSLLISLSAGIIVTRVPGEKRQNL
                     ATELSSQIARQPQSLILTAVVLMLLALIPGFPFITLAFFSALLALPIILIRRKKSVVS
                     ANGIEAPEKDSMVPGACPLILRLTPTLHSADLIRDIDAMRWFLFEDTGVPLPEVNIEV
                     LPEPTEKLTVLLYQEPVFSLSIPAQADYLLIGADASVVGDSQTLPNGMGQICWLSKDM
                     AHKAQGFGLDVFAGSQRISALLKCVLLRHMGEFIGVQETRYLMNAMEKNYSELVKELQ
                     RQLPINKIAETLQRLVSERVSIRDLRLIFGTLIDWAPREKDVLMLTEYVRIALRRHIL
                     RRLNPEGKPLPILRIGEGIENLVRESIRQTAMGTYTALSSRHKTQILQLIEQALKQSA
                     KLFIVTSVDTRRFLRKITEATLFDVPILSWQELGEESLIQVVESIDLSEEELADNEE"
     gene            complement(6671..7039)
                     /gene="ssaM"
                     /locus_tag="OPV72_003803"
     CDS             complement(6671..7039)
                     /gene="ssaM"
                     /locus_tag="OPV72_003803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system apparatus
                     protein SsaM"
                     /protein_id="HCR9915982.1"
                     /translation="MDWDLITERNIQLFIQLAGLAERPLATNMFWRQGQYETCLNYHN
                     GRIHLCQILKQTFLDEELLFKALANWKPAAFQGIPQRLFLLRDGLAMSCSPPLSSSAE
                     LWLRLHHRQIKFLESQCVHG"
     gene            complement(7097..8113)
                     /gene="ssaL"
                     /locus_tag="OPV72_003804"
     CDS             complement(7097..8113)
                     /gene="ssaL"
                     /locus_tag="OPV72_003804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system apparatus
                     protein SsaL"
                     /protein_id="HCR9915983.1"
                     /translation="MVKIKEVAMNIKINEIKMTPPTAFTPGLVIEEQEVISPSMLALH
                     ELQETAGAALYETMEEIGMALSGKLRESNKFTDAEKLERRQQALLRLIKQIQEDNGAA
                     LRPLTEENSDPDLQNAYQIIALAMALTAGGLSKKKKRDLQSQLDTLTAEEGWELAVFS
                     LLELGEVDTATLSSLKRFMQQAIDNDEMPLSQWFRRVADWPDRGERVRILLRAIAFEL
                     SICIEPSEQSRLAAALVRLRRLLLFLGLEKECQREEWICQLPPNTLLPLLLDIICERW
                     LFSDWLLDRLTAIVSSSKMFNRLLQQLDAQFMLIPDNCFNDEDQREQILETLREVKIN
                     QVLF"
     gene            complement(8079..>8363)
                     /gene="ssaK"
                     /locus_tag="OPV72_003805"
     CDS             complement(8079..>8363)
                     /gene="ssaK"
                     /locus_tag="OPV72_003805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system apparatus
                     protein SsaK"
                     /protein_id="HCR9915984.1"
                     /translation="QQSVDSVMCHRLARQATAMAEEGALYLRIHPEKEALMRETFGKR
                     FTLIIEPGFSPDQAELSSTRYAVEFSLSRHFNALLKWLRNGEDKRGSDEY"
BASE COUNT         2419 a         2098 c         1716 g         2130 t
ORIGIN      
        1 cgttagtaga actaatatac ttttgagcgg cattgagaag aaaaacacat tcaattgttg
       61 tgccgaccga tttaaaagac ctaaagccag atcggctaat accatacata ttatggcagg
      121 aagagagaag ctgatgcata attgataaag cgttctccac tctgcctgga tatattttaa
      181 aaattgccga tcaaataata aagtacgccc tggcggtaaa tattggtatg actcatacag
      241 aatgtttaat ataaactcca tgccgccgct tataaagaaa ataacacaca aaaactggct
      301 gaaaagcaag ccaaaaagtg aggtttcagc ttccattgta gaattgaata tcgtacccat
      361 tgtcgcgcca cgtaaagtat caagcagaaa ccccgccata tcaacggccc aaaagggaac
      421 cgccgcacaa aacccaatta aaaaaccaat aatcacctct ccggtgacta accctaacca
      481 gctgtaatct ttaccaatat gcatcataat cttctgctgg taaatgattg gtaatatggg
      541 aaaggtaagt gacataagca cgccattacg taaaagcgcg gcccctaaac tgccactttt
      601 taatagagga agtaataaag aaaggctcaa tggtcgaata aaagccacag ccaatgcaat
      661 aagccactca tttacctgtt gtgtcattca accatgctct ccaattcgta acattatctg
      721 ccgggtataa ttcaacagga ttccgctaag ccatgggtag ctgaccatca aagttattgc
      781 aattgctaat aatttaatca tgaactgtag cgtttggtcc tgaatttgag tcaaggcctg
      841 gacaagactt acgatgacac caactaccga tgccaccaac accaccggca tagacgtaaa
      901 aaggacgatc cataaaagtt gcgttataaa ttgcgtcaat tcagaatcat tcatgaaaag
      961 ctctgtacca attgcgccag tgtcagatcc caaccgcctg ccagtaaaaa tattagcagc
     1021 ttaaacggta atgaaatggt cattggcgat accatcatca tccccatagc cagcagtata
     1081 tttgaaataa gcaggtcaat agccagaaag ggaagataaa taagtaatcc aatccgaaat
     1141 gcctgcgtta actgactcac cgtaaatgcc ggaattaata tgagcaaaga atcaggtttt
     1201 atctttcttt ttatgtcttc aggccaggtt cgttttatca aattccgaaa ataattggct
     1261 tccttctctt cagagttttt ttgcaaaaac tgtcgataag gcgctaatgc tttactgtcc
     1321 cactcagacg tccagaaagg agcgccagcg acctgaaccg gatgccagcg ctcttttaca
     1381 gctaatagcg tcggccccat aatgaataag gaaagtacaa gcgcgaagcc atacagtgcg
     1441 atatttggag gaacttgttg aatacccaga gcatttcgta aaatcgaaaa taccaccgcc
     1501 agtttaagga aagaggttcc catgacgata atgagaggca gtattgaaag cagaaacaat
     1561 ataccaatca gttgcaaagg cgaatcgggt aaagacatac tgtatctctc atgacacgac
     1621 ctggaacgct attatattgt tcgcatatta tttttcttat caggtttacg ctgtattttt
     1681 gcaaagatac caacgtgtaa tacgtaccat gaattcattc ccacaggcaa tcaactcacc
     1741 ttgcccaata atacggtcat ttactcttat cgtcacttct ggcgcaaaac atccgcctac
     1801 aggcaaaacg tcccccgttt taagttgtcg taattgtcca atttccagac tcgcacgtcc
     1861 aatctcaaag agcacctgtt gtggtatctg ctcaagttcg actgaagacg ttccatcact
     1921 ctttaacatc gggctccctg acgcaagtag cgtttcgata tcctggacta attcgtcaaa
     1981 tttcatcgtg ttatcctctg tcagcaacac cctcgcgtaa atacccccag gtagttgaat
     2041 agcaaaaaaa ccgagtctga tgtcgccaaa gcaatgaatc cgaacgccca tgccgatttc
     2101 gatagactca agttcaatta atgtaagctg acaccagcct aaatatacag ggactaccac
     2161 aggaggagca ggataaatct gttgacgctc agcagaaagc tctccgacta tattgcgcaa
     2221 aaaacccgtt ggccatgtaa aaataatgct atggaactca tgttcttcaa ctgtccattt
     2281 aatatgcaac gctagctgat gtggtagatt actgcaggat gttggcggct cgttctgaca
     2341 gagggttgca tcactggctt gcaataacgg cgccagcccc cattcagcta ttccatatag
     2401 caattcaggc tcaatagccg atcgattagc ggtgccaatt agcccttcac accagcgctg
     2461 ccagcattgt tctgcaatcc acaccctacc cagctcatta tgataattta tggtaaataa
     2521 tgtcccttgc tgtactggat attgttgcat actcaatgtc agctcaccaa tggtagcgcc
     2581 ttgtgttgga agtatctcca cccacggacg ctcttcattc gctattctta acatagaata
     2641 tctccaggga aattatatac cccatatgca gcaactgaga ctccagccac tgctttagcg
     2701 ctttcatcga acggtaaatt tcatgatgag ggacattgat tcttaactgg attagccctc
     2761 ctgactcaca gacttcacac tctacaccgt caagataacc gccactaaca cgataacgtt
     2821 gcgtgaaaac cacgttctta ttcaatgctg caggaggatt attctcacca atgggtaatg
     2881 cctggtgcat gagttgttca aagtccatac gttccgcctc cgcctcgtta tcatcctgat
     2941 aagactggca tggcaaccca agacttccct caactttggt aatacgcatc gcttaatacc
     3001 atagtaattt tttctttctt tttcataagc gcattaaaat tcttctgtaa ttcgcttcgc
     3061 ctggagacaa gctgctgata ctgattctct aactgctgcc gttgcgtcaa aaagctctgc
     3121 gcctgagtga atagtccggc catttgttgt ttcttatcca acaataaatg acaagataac
     3181 gtaccttgcc agcccattaa ttctttcagt ctggtagtca ctgctaaagc gcgcgtctgg
     3241 caaatctgct gttcagtaat aatcgcctgt tgctgctgat caagcacggt aagtttgctg
     3301 cgtaattgct tttcacgccg cgcgattatc tccagcaaag tttccatgat cactcggtga
     3361 gtatttgatg taatttttct atgagtagct cgggtccgca tacttcatcc ttactttgtc
     3421 gcaaaaatgt gcaaatatcc ggataggtat caatggcttt atcggtatca gtatcaactc
     3481 ctcgctggta ttccccaatg cgtattaaca gttcaacctc ctggtaaagc gccaggcgcc
     3541 gtcgcaatat agccgccagt tgacgatgct catggctggt aacgactgga aaaacgcggc
     3601 tgagcgttgc caacacgtca atggcaggat aatgccccct ctctgcaagc cgccgggata
     3661 gcacaatatg tccgtcaagc agtgaacgga cttcatccgc caacggctca ttcatatcat
     3721 cgccttccac caggaccgta taaaatgcgg taatactgcc tttttccccc attcctgtac
     3781 gttctaaaag tcgtggcaat gcactaaata cgcctggcgg atattctcca gaaactgcgg
     3841 tctctccggc ggccagagcg atttcccgtg cggccctggc ataacgcgtc agtgagtcgg
     3901 caagcaagac gactcgtttt ccattatcgc gaaaaaattc tgctatcgtg gtggccacaa
     3961 acagcgccct cacgcgctct aaggcgggtc tgtcagaggt tgcgacaaca atgacacaac
     4021 gttttcgggt ctcttcagac agtgtaaaat cgatgaactc gcggacttct cgtccacgtt
     4081 caccaattaa caccagaaca ttgcagtctg cgtctggcgc attacacagc atcgccagaa
     4141 gcgtgctttt ccccacgcca ggagcagaaa aaatacccac tcgttgccct tcaccacagg
     4201 tcgcaacgct atcaatagcg cgaatccccg tcattaatgg ttgagtgata ggctgtcgaa
     4261 ccattgcggg aggaggcatt gcatcatagt ctttccagca gacgtcgggc agttcgcagc
     4321 catcaagggg acgaccaaaa ccatcaatga ctcgccctaa taacgcttcg cccacgggaa
     4381 cctgatggcg tcgccttaag gccatcactt gctgcccgca gtgaagcccg atagtactcg
     4441 taaaaggaga tagcaaagct ttgctgccat taatccccac gacttcagca agttcttctc
     4501 caggctttat acagcacaac tctcccataa ataccccagg caaccacgca tttaacaacg
     4561 ttgcgctgac atcttgaatt cggccccatc gacaataacc atcggggggc ggatatttca
     4621 gcctcagacg ttgcatcaat tcattcttca ttgtccgcca actcctcttc gctaaggtca
     4681 atactttcta ccacttgtat aaggctctcc tctcctaatt cctgccatga caaaatcggt
     4741 acgtcgaaca aggtggcttc tgtaattttt cgcaagaaac ggcgggtgtc gacagaagtg
     4801 acaatgaata atttggctga ctgcttcagc gcctgctcaa taagttgcag gatctgcgtc
     4861 ttatgacgag acgacagcgc agtataggtc cccattgccg tctggcgaat ggattcacgc
     4921 acgaggtttt caataccttc gccgatccgc aaaatcggca gcggttttcc ttccggatta
     4981 agacgacgca gaatatgacg gcgaagcgcg atacggacat attctgtcaa catcaggaca
     5041 tctttttcgc gtggcgccca gtcaattaat gtgccaaaaa taagacgtaa atctctaata
     5101 gaaacccgct ctgatacaag ccgttgcaaa gtttcagcga ttttattaat gggtaactgg
     5161 cgctgaagtt ctttcaccag ttcagagtag tttttttcca tcgcattcat tagataacgc
     5221 gtttcctgaa caccaataaa ctctcccata tgccgaagca ggacacattt taataaggca
     5281 gagatacgtt ggctgcccgc gaaaacgtcc agtccaaaac cttgcgcctt atgagccatg
     5341 tcttttgaaa gccaacagat ctgccccatt ccgttcggta acgtctggct gtcacccacc
     5401 acactagcgt ccgcgcctat caataaataa tccgcctggg cgggaataga taaactaaac
     5461 acgggttcct gatatagcag taccgtcaat ttttcggtgg gttcaggcaa aacctcaata
     5521 ttcacctcag ggagagggac gccggtatcc tcaaataaaa accatctcat ggcatcaata
     5581 tcacgaatca ggtcggcaga atgtaacgtc ggggtaagac gtaagattag aggacatgcg
     5641 ccgggaacca tactatcttt ttccggcgct tcgatgccat ttgcggaaac cacagacttt
     5701 ttgcggcgaa tgaggataat tggcaatgct aacaacgctg aaaagaaagc gagagtgata
     5761 aaaggaaagc caggaattaa agcgaggagc attaaaacca cagcggttaa tatgagcgac
     5821 tgaggttgtc tggcaatttg agaactcaac tctgtcgcca ggttctggcg tttctcaccc
     5881 ggaacacggg tgacaataat tcccgcgcta agggaaatca gcagcgatgg aatttgccca
     5941 cataaaccat ctccgattga cagtacgcta taagtgtgaa cagcctcact catcgacata
     6001 tcatattgta cgatagcgat aataataccg ccgataatgt tcaccagaac aacaataata
     6061 ccggcaatcg tatcgccttt aacaaatttc attgcaccgt ccatcgcacc gagaaaacgg
     6121 ctttcctgct ggacgtgctg tcttaatgta cgggcatggt ctgcatcgat aactccggca
     6181 cgcaaatcgc catcgatact catttgtttg cctggcatcc catcaagcga gaaacgtgcg
     6241 ctaacttccg ccaccctctc gatacctttt gtaatgacaa taaattgcac aatagtaatg
     6301 atggtaaata cgaccaaccc aacggtgaga tttcctccta cgacaaactt accgaaagca
     6361 tccacaatat taccggcatt atgttgtaac agtaccagcc gtgatgtgct gattgtgagt
     6421 gacaaacgat ataatgtagt aataagtaat aaagacggaa ataccgataa atcgagaggg
     6481 tcactaagat aaataacaat taaaagcagg atcactgaaa acataaggtt gatagtaatc
     6541 aggatatcaa ccatccaggt cggcaaaggt aacagcatca tcacgatagc gattaataac
     6601 accgtcgcca gaaccatatc ctgacgaccc gcgcatacac tgagccactg ttgcgccctg
     6661 attccctcac ctaaccatga acgcattgcg actccagaaa ttttatttgt cgatgatgta
     6721 atcgtaacca gagctcggcg gagctggaaa gaggtggaga acaactcatt gcaagcccat
     6781 cgcgcaacaa aaataatcgt tgaggaatac cctggaacgc tgcgggtttc cagttagcca
     6841 acgctttaaa aagcagttct tcgtctaaga aggtttgctt gagtatctga cataagtgaa
     6901 tacgaccatt atgatagttt agacaggttt catattgtcc ttgccgccag aacatattgg
     6961 ttgctaaagg ccgttcagct aatcctgcta attgaataaa aagctgaata ttacgttcag
     7021 taatgagatc ccaatccatc ctgacgcctc atgatgagcc agaaagccaa tttacctaaa
     7081 tattgaaagc caggtatcag aataaaacct gatttatctt tacttcacga agcgtttcga
     7141 gaatttgttc acgttgatct tcgtcgttaa aacagttatc gggtatcagc ataaactgcg
     7201 catcaagttg ttggagtaac cgattgaaca tcttcgatga agaaactata gcggtaagtc
     7261 tatcaagcaa ccaatcgctg aaaagccagc gctcacaaat gatatcgagt agtagcggca
     7321 gtaatgtatt aggcggcaac tggcaaatcc actcctcacg ctggcactct ttttcaaggc
     7381 caaggaataa caacaaacga cgcaagcgta ctaatgctgc ggccaaacga ctttgctccg
     7441 agggttcgat gcatatgcta agttcaaagg ctattgctct tagcaaaata cggacccgtt
     7501 caccgcgatc cggccagtct gccacgcgtc tgaaccactg cgataagggc atttcatcgt
     7561 tgtctatcgc ctgttgcata aaacgcttca gcgaggacag cgtagcggta tccacttcgc
     7621 caagttccag taaactaaaa acggcaagtt cccatccctc ctccgctgta agcgtatcca
     7681 gttgcgattg caaatcgcgt tttttctttt ttgacaaccc gccggcagta agcgccattg
     7741 caagagcgat aatttgatac gcattctgta aatcaggatc actattctct tcggtaagcg
     7801 gacgcaacgc tgccccatta tcctcctgta tttgttttat caaacgcagc aaagcctgct
     7861 gcctgcgctc cagtttctca gcatcagtga atttattact ttcgcgcagt ttaccactca
     7921 gcgccattcc tatttcttcc atcgtctcat agagcgctgc ccccgccgtt tcctgtaact
     7981 catggagagc taacattgaa ggcgaaataa cctcttgttc ctctataacc aggccagggg
     8041 taaatgctgt agggggcgtc atttttatct cattaatttt aatattcatc gctacctctt
     8101 ttatcttcac cattacgtaa ccatttcagt aacgcgttga aatgacgaga aagtgaaaac
     8161 tcaacggcat atcgtgttga ggaaagttca gcctgatcgg gagagaaacc aggctcgata
     8221 atcagcgtaa accgcttgcc aaaagtttca cgcatcaatg cctctttttc aggatgaata
     8281 cgcaaataaa gcgctccctc ttccgccata gccgtggcct ggcgtgccag acgatggcac
     8341 ataacactgt ctaccgactg ttg
//
LOCUS       DAJVBX010000198         8269 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.198, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000198 DAJVBX010000000
VERSION     DAJVBX010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 8269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8269
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.198"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            215..757
                     /locus_tag="OPV72_003806"
     CDS             215..757
                     /locus_tag="OPV72_003806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein BcfA"
                     /protein_id="HCR9915985.1"
                     /translation="MKKPVLALMVSAIAFGGMLSTAQADTTTVTGGTVNFVGQVVDAA
                     CSVSADSVDQTVTLGQVRASKLTEAGMAANQKEDFTIKLEDCDTQTSQNAAVIFNGQQ
                     DANQPGSLANTAGAGSATNVALQLYGPDGQALNIGESSSTVTLNDGENVIPLSVDYIA
                     TGTATAGNVTATATFSMVYS"
     gene            858..1544
                     /gene="bcfB"
                     /locus_tag="OPV72_003807"
     CDS             858..1544
                     /gene="bcfB"
                     /locus_tag="OPV72_003807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis chaperone BcfB"
                     /protein_id="HCR9915986.1"
                     /translation="MKKNVPIFLRLLLLLSAAGLSFAVQAGGIALGATRVIYPQGSKQ
                     TSLPIINSSASNVFLIQSWVANADGSRSTDFIITPPLFVIQPKKENILRIMYVGPSLP
                     TDRESVFYLNSKVIPSVDKNKLTGNSLQIATQSVIKLFIRPKNLAEAPAHAPATLRCR
                     NERGQLTITNPSPYYVSMVELYSAGKKLPNTMVPPKGAITLPATPGQVSLRTVNDFGA
                     TTPARVCPAS"
     gene            1549..4170
                     /gene="bcfC"
                     /locus_tag="OPV72_003808"
                     /pseudo
     CDS             1549..4170
                     /gene="bcfC"
                     /locus_tag="OPV72_003808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459028.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial usher BcfC"
     gene            4171..5178
                     /locus_tag="OPV72_003809"
     CDS             4171..5178
                     /locus_tag="OPV72_003809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein BcfD"
                     /protein_id="HCR9915987.1"
                     /translation="MKIPLLFALLAGSVVSQYAHADVCKNVNGVPSSINYDLTTTLTA
                     EQNQVGKTVQLEKSQEVNVQAVCPAGASTYSQTYRSYVSPYPVVETSGNWKYLKLDPD
                     YLEGGMRIEDSSAGDIYPPMNNVLMGYDENVKAGQPFYVRDSNLEFQLKIVKPFVGTV
                     NISPKTMFNVYVMTAAGDPLTDVVYSILYSGTVTVPQSCEINAGQTILVNFGALYSGN
                     FNHAGQKPEGVRAKKFSVPVKCSGLDSQVNLTMRLIATPDSHFPQAIASDNADVGVVV
                     ETDEGNALIPNDVQSVAPFITDSAGRANITLQAYPVSTTGETPAEGAFTALASLRVDF
                     D"
     gene            5179..5724
                     /locus_tag="OPV72_003810"
     CDS             5179..5724
                     /locus_tag="OPV72_003810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein BcfE"
                     /protein_id="HCR9915988.1"
                     /translation="MNRSHCALFVMGLILCPQINASADDLAYNLEFTGTIVAQTCDID
                     ISSLSQSIDLGQFAVGDFPSTGTTTKFKPFNINLKNCSRGITGAKIWFTGEPDPDNPA
                     LLAITDTGMGSGNMLASGVGVEILNDDQDTISINNADSVVYPLKAGRNTLSFYIRYKS
                     TRPTVTSGNATAVMYFDMQYE"
     gene            5740..6258
                     /locus_tag="OPV72_003811"
     CDS             5740..6258
                     /locus_tag="OPV72_003811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein BcfF"
                     /protein_id="HCR9915989.1"
                     /translation="MRNDILYGIGMLLAASGVQAHDGRVYVSGTITDNTCSLSPGSEN
                     INVAMGAVSQRQFYRAGDGSAWQPFAIDLQNCGSTASGVTVSFSGAGDSRNTDLLALT
                     AGESDASGIGIALYDQNKTLIPLGQESDVVTLSPGQASAHLQFYARYLADGGTVTPGD
                     ANASATFILAYE"
     gene            6224..6955
                     /gene="bcfG"
                     /locus_tag="OPV72_003812"
     CDS             6224..6955
                     /gene="bcfG"
                     /locus_tag="OPV72_003812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone BcfG"
                     /protein_id="HCR9915990.1"
                     /translation="MPPQPSFLPMNKFFLHCAIYWCLLPISWAQAGVVIGGTRFIYHA
                     GAPALSVPVSNHSEASWLIDTHILPGGRWPGTKNEGNITPFVVTPPLFMLSARQENSM
                     RVVYTGGPLPADRESLFTLSIAAIPSGKPEANRVQMAFRSALKLLYRPEGLAGNPQQA
                     YRHLIWSLTPDGATVRNPTPYYVTLFLLRANERAQDNAGVVAPFATRQTDWCRHAVRC
                     TVRWQSINDYGRVMTAQTVDLTRIH"
     gene            7020..7865
                     /locus_tag="OPV72_003813"
     CDS             7020..7865
                     /locus_tag="OPV72_003813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HCR9915991.1"
                     /translation="MYYHALKLSRLAMLTLAGVAVSASAIAADSAPTSQIGPTAEAYI
                     VSHPDKVGEVVATYLAEHPEFLVAASETLHQRQQIAQQQAYVQLALQYRAELLSSSSP
                     SVGPSEAKAAVVMFFDYQCSWCSKMAPVVENLIKANPDTRFIFKEFPIFSSRWPVSGL
                     AARVGEQVWLTQGGAKYLDWHNALYATGKVEGALTEHDVYTLAQHYLTPTQLAAVKEA
                     QSSGAVHDALLTNQALAQHMDFSGTPAFVVMPQTQNGDVKRVTVIPGSTTQDMLQMAI
                     QKAKG"
     gene            7904..8191
                     /locus_tag="OPV72_003814"
     CDS             7904..8191
                     /locus_tag="OPV72_003814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9915992.1"
                     /translation="MKSMRCVIPVILLSFIVHEGTAKPTAQIHFMGSVVEAGCWNDVG
                     TLEIQCYNKEGVERYIIVENIITPISSPHATVKRDYLDEDKQLTVLRIVYD"
BASE COUNT         2012 a         2047 c         2242 g         1968 t
ORIGIN      
        1 gcttgctaat aattaataac atcgttatct cattataacg taaagattaa ctcacgacgt
       61 tgagtagctg ttttattgcc tctgacattt atatcagaac aagaagacac ttttttcgca
      121 taagaaaagt cgtgatattg ctgtgaagaa atatcagcag ccgtttcgtt aaaaaatctg
      181 attaccctca tttttatatt taaaaggagc ttgaatgaaa aagcctgtac tagcattaat
      241 ggtctctgcc attgcctttg gcggaatgtt gtccaccgcg caagcggata ctacaaccgt
      301 cactggcggt acggtaaatt ttgtcggaca ggtcgttgac gccgcctgtt ctgtttccgc
      361 tgactctgtc gatcagaccg tgacattagg ccaggttcgc gccagtaaat taaccgaggc
      421 cggtatggcg gcgaatcaaa aagaagattt caccattaaa ctggaagact gcgatactca
      481 gaccagccag aatgcggcgg tgatttttaa tggccagcag gacgcaaacc agccgggttc
      541 gctggcgaat accgctgggg caggttcggc gacgaatgtg gcactacaac tttatggacc
      601 ggatggccag gcgctgaata ttggtgaatc gtccagtact gttaccttga acgatggcga
      661 aaacgttatt ccgcttagcg tggattatat cgctaccggt acggcgactg ccggtaatgt
      721 taccgcgacg gcgacattta gcatggttta ttcctgattc cttatcggga tttttttctc
      781 gtctgttggg aggcgagaaa ggggcgttac gcgcgtcact gcgcgtaaca aaccgacggc
      841 atcaggatat tacgcagatg aaaaaaaacg taccgatttt ccttcgatta ttgctactgc
      901 tgtcggcggc cggcctgtcg tttgccgtgc aggcgggagg cattgcgctg ggcgcgacca
      961 gggtgattta tccgcaggga agtaagcaaa cctccttgcc gattattaat tcttctgcca
     1021 gcaatgtttt tttaattcag tcgtgggtcg ccaatgccga tggttcacgc tcgacggatt
     1081 ttatcattac gccgcctctc tttgtgatcc agcctaaaaa agaaaatata ttacgtatta
     1141 tgtatgtcgg gccgtcatta ccgaccgatc gcgaaagcgt gttttattta aacagtaaag
     1201 tgataccctc tgtcgataaa aataaactga ccggcaactc cctgcaaatt gcgacgcaaa
     1261 gcgtgattaa gctatttatc cgcccgaaaa atctggcgga ggcgccagcc catgccccgg
     1321 caacgcttcg ctgccgtaac gagcgcggcc agctaacgat tactaaccct tcgccgtact
     1381 acgtttcgat ggttgaactg tacagcgcgg ggaaaaaact gccgaatact atggtaccgc
     1441 cgaaaggcgc gatcactctc ccggcgacgc ctggccaggt atctttgcgc acggtaaacg
     1501 attttggcgc aacgacgcca gcacgcgttt gtccagcttc atgatgttat gcgtaatcag
     1561 cttttcatga cgcgatatta ctccagcgta gctaaacccg tattaactcc gctggcgttg
     1621 gctatcgcac tggcgcctgc gcctgggtgg gcggaaaact atttcaaccc ggcatttctg
     1681 tctgacgacc cgtctgcggt ggccgactta tcgacctttt cccgtaatgc ccaggcggcg
     1741 ggaatgtatc gcgttgacgt ttacctgaac aatacgtttc tcgcgaccag agacattgcc
     1801 ttccaggcgg tgaagacgac gggaaaaagc gcgcccaccg atgacagcgg attacgcgcc
     1861 tgcctgacgc ctgaaatgct taaaaatatg ggggtaaaca ccggggcatt tccactgttg
     1921 gcgaaggcgg cggcgggaag ttgtccggat ctcgccagtg cgataccggc cgcccggacc
     1981 cgctttgatt ttgcgcagca acgtctcgac attagcatcc cgcaggcggc gatggttgcc
     2041 agcgccagag gctatatccc accgcaatac tgggatgaag gtattaacgc gttgctattg
     2101 aattacacct ttaccggcgc gaatagtcag gatcggagcc caggcggcag tgcggagaac
     2161 agctattttc ttggattgaa tagcggcctt aatctggggg cctggcggtt acgcgactac
     2221 tccacatgga acgcgaatag cggcgatcag aatagcgaca gcgactggca gcacatcagt
     2281 acttatctgg aacgtgatgt ggtctttttg cagggagaac tgacggcagg cgatagttat
     2341 accccctccg cattattcga tagccttcct tttcgcgggc tacaactggc gtctgacgac
     2401 aatatgttgc cagacagcat gaagggcttc gcgccgacca ttcacggcat tgccagaagc
     2461 aacgtgtaag tgaccattcg gcaaaacggc tacatcatca atcagcgcta tgtgccgccc
     2521 ggggcattta ctattaatga tctctatcct accgccgcca gcggcgattt gactgtggaa
     2581 gtcaaagagt ccgacggttc tattaatcgc tataacgtgc cctattccgc cgtgccgatt
     2641 ctacaacgag aagggcggct gaagtatgcg gcgacggtgg cggagtatcg tagcgatagt
     2701 agtcaaaaag agaaggtgaa attcagtcag gcgaccttga tatgggggtt accgcatggt
     2761 tttacgctgt atggcggaac acaactttcc agtcattatc acgcgctggc gatcggcagc
     2821 ggcgcaaatc tgggcgactg gggcgcggtg tcgctggatg tcacccaggc taccagtacg
     2881 ctggcggata ataactccta ccaggggcaa tcgctgcgtt tcctgtatgc caaatcgctt
     2941 gcacagtcag gaaccaattt acagcttatg ggctatcgct attcaacctc gggcttttac
     3001 acgttggatg ataccacgtg gaaacggatg agcggctatg acgatgacaa tcggactgac
     3061 agcgataaaa gcaggccgga atgggcggat tattacaatc tttattatac caggaggggc
     3121 aaagtacaac tcgatatcaa tcaacagcta ggcgggttgg gatcgctttt tattaccggc
     3181 agtcagcaaa gttactggca cactgatgaa aaggattctt tgttgcaggt gggatacagc
     3241 gatacgctgg cgggtattgc atggagcgtt tcttacaaca ataacaaatc cgcaggcgat
     3301 gcggagcgcg atcaaatttt cgccctgaat atctcggtgc cgctaagtca atggctgcaa
     3361 catgatgatg aggtcacgca ccatcacaat gtttacgcta cctttagcac cagtacggac
     3421 aaacagcata acgttacgca gaatgcgggc cttagcggca cactactgga cgaaaacaat
     3481 cttagttaca acatacagta aggctatcag aatcacggta ttggcgaaag cggcgccgcc
     3541 agcctggaat acgatggggc gaaaggcaac gccaatattg gctataacgt tagcgataac
     3601 ggcgattacc agcaggtgaa ttatggcctg agcggcggcc tggtggcgca cgcgcatgga
     3661 gtgacgctaa gccagccgtt aggcaatacc aatattttga ttgccgcgcc gggcgcagcc
     3721 aatgtcggcg ttgtcgacca gccgggtatt catacggacg cgcgtggcta tgcggtggtg
     3781 ccgtatgcga cgacatatcg ccaaaaccgt atggcgctgg acgttaacgc catggctgat
     3841 gatgtcgata ttgatgacgc ggtgactcgc gttgtgccga ccgaaggcgc gctggttctg
     3901 gcccgcttta aagcgcgagt cggcgtgcgt gccctggtaa cgctgaatca taatggtaag
     3961 cctgtaccct ttggcgcaac ggtgacggtg aatgatcgcc atgcggaggc gattgttgac
     4021 gaggccgggg aggtctatct ttccgggttg tcagcgcaag gcgttctgca cgttcgctgg
     4081 gggaacctgc cggatcaaca gtgcgtcgcg tcctatcatc tctcttcctc ccgtcagatt
     4141 ctgagtcgac aatatgcgga gtgtcattaa atgaaaatac ctcttttatt tgctctgctg
     4201 gcggggagtg tcgtatcgca gtacgcacac gcagacgtgt gtaaaaacgt taacggcgtg
     4261 ccttccagta ttaattacga tttaacgacc actctgacgg cagaacaaaa ccaggtggga
     4321 aagacggttc aactggaaaa aagccaggaa gttaatgtac aggcggtgtg tcccgccggc
     4381 gcgtcgacct atagccagac ttatcgctcc tatgtgtcgc catatccggt cgtagaaacg
     4441 agcggtaact ggaaatattt aaagctggac ccggactacc ttgaaggcgg aatgcgaatt
     4501 gaggattctt cggcgggcga tatctatccg ccaatgaaca atgtcctgat gggatatgat
     4561 gaaaatgtga aagcgggtca accgttttac gttcgtgact caaatctgga gtttcagctc
     4621 aaaattgtta aaccgttcgt cggcacggtg aatattagtc ctaagactat gttcaatgtt
     4681 tatgtcatga ccgccgcagg cgatccgctg acagatgtcg tgtacagcat tctttatagt
     4741 ggaacggtga ccgtaccgca aagctgcgaa atcaacgccg gacaaacgat tctggtgaat
     4801 ttcggtgcat tatacagcgg caatttcaac catgcaggcc aaaagccgga gggggtacga
     4861 gcgaaaaaat tcagcgtacc ggtaaagtgc agcggtctgg attcgcaggt caatttaacg
     4921 atgcgtctta tcgctacgcc ggatagccac tttccccagg ctatcgcttc ggataatgcc
     4981 gatgtcggtg tagtggtcga aaccgatgaa ggaaacgcgc ttattcccaa tgatgtacag
     5041 agcgtcgcgc cttttatcac cgatagcgcc ggacgcgcta acatcacatt gcaagcctac
     5101 ccggtgagta caacaggtga aacgccagcg gaaggggcgt ttaccgccct ggccagcctg
     5161 cgagtggact ttgactaaat gaacagatca cactgcgctc tttttgtcat gggactaatc
     5221 ctgtgtccac aaatcaatgc cagcgctgac gacctcgctt ataacctcga atttaccggc
     5281 actattgtgg cgcaaacttg cgacatagat atttccagtc tcagtcaaag tattgattta
     5341 gggcagtttg cagttggcga ttttccttcg acaggaacaa cgacaaaatt taagcccttt
     5401 aatatcaacc tcaaaaattg ttcccgagga attaccgggg cgaagatctg gtttaccggc
     5461 gaacccgatc cggacaatcc cgcgctactg gcaataaccg ataccggaat gggaagcgga
     5521 aacatgttag caagcggggt aggggtggaa attctgaatg atgatcagga taccatcagt
     5581 atcaataatg ccgactcagt ggtctatccg ttgaaagccg gacgcaacac gctgtctttt
     5641 tatattcgct ataaatcgac ccggccgacg gtcacgtccg ggaacgcgac ggcggtcatg
     5701 tatttcgata tgcagtatga atgaggagcc atcgtaatta tgcgtaacga tatcctgtac
     5761 ggcatcggga tgctgctggc ggcatccggc gtccaggcgc acgatggccg ggtctatgtc
     5821 tccggaacca tcacggacaa tacgtgttcg ctctctccag gctcggaaaa tattaacgtg
     5881 gcgatgggcg cggtttctca acggcagttt tatcgcgcgg gcgacggttc cgcctggcaa
     5941 ccttttgcta tcgatttaca gaactgcggt agcactgcca gcggcgtaac ggtcagtttt
     6001 agcggtgcag gggatagccg taatacggat ttattggcgc ttaccgcagg ggaaagcgac
     6061 gcttcaggaa ttgggattgc gctttatgat caaaataaaa ctttaatccc actggggcag
     6121 gagagtgatg tggtgacgct cagtccgggc caggcgtcgg cgcatctgca attttacgcg
     6181 cgttatcttg ccgatggcgg cacggtaacg cccggggacg ccaatgcctc cgcaaccttc
     6241 attcttgcct atgaataagt tctttttaca ctgcgcgata tattggtgct tgcttcccat
     6301 atcatgggcg caggctggcg tggtaattgg cggtactcgc tttatctatc atgcgggcgc
     6361 cccggcatta agcgtaccgg taagtaacca ttcagaagcg tcctggttaa ttgatacgca
     6421 tattttacct ggtggccgct ggcctggaac caaaaacgaa gggaatatta cgcccttcgt
     6481 ggtcacgccg ccattattta tgctttcagc gcgccaggaa aactcaatgc gggtggttta
     6541 taccggcgga ccgctacccg ccgacaggga aagtctgttt accttgagta tcgccgctat
     6601 tccctccggt aaaccggaag cgaaccgtgt acaaatggcg tttcgttcgg ctttaaaatt
     6661 gctctatcgc cctgagggac tcgccggcaa tccgcagcag gcctaccggc atctgatctg
     6721 gtcgcttacc cccgatggcg cgacggtacg caatccgaca ccctattacg ttacgctctt
     6781 tttattacgc gctaacgagc gcgcccagga caacgccggg gtcgtggctc cctttgcaac
     6841 gcgtcaaacg gactggtgcc ggcacgcggt tcgctgcact gtgcgctggc aaagtattaa
     6901 tgactatggg cgggtaatga cagcgcaaac cgtggatctg acgcgtattc attaacctat
     6961 ttttcaggcg tctcccgata gcgggaggct ttccgatctt atcgaacgag acttttatta
     7021 tgtattatca cgcgttaaaa ctttcccgac tggcgatgtt gacgttggca ggcgttgcag
     7081 tatccgcctc ggcaatcgcc gccgattctg ccccgacgtc gcaaattggc ccgacggcgg
     7141 aagcctacat cgtcagtcat ccggataaag tgggagaggt ggtggcaacg tatttggccg
     7201 aacatccgga atttttggtc gccgccagcg agacgttaca tcagcgtcag cagattgcgc
     7261 aacaacaggc gtatgttcaa ctggcattac agtatcgtgc tgagttgctc agtagcagca
     7321 gtccttccgt tgggcccagc gaggcaaaag cggcggtggt aatgttcttt gattaccagt
     7381 gctcgtggtg cagcaaaatg gcgcctgtgg tcgaaaacct gattaaggcg aacccggata
     7441 ctcggtttat tttcaaagag tttcctattt tttcctcccg ctggccggta tccggactgg
     7501 cggcaagagt cggcgaacag gtatggctta cacagggcgg ggcgaaatat ctcgactggc
     7561 ataatgcgct ttatgccaca gggaaggtgg aaggcgcgtt aacggaacac gatgtctaca
     7621 ccctggcgca acattatcta acgccgacgc agctggccgc cgtaaaagaa gcgcaaagca
     7681 gcggtgcagt acatgatgcg ctcctcacta accaggcact ggcgcagcat atggacttta
     7741 gcggcacgcc tgcttttgtc gtcatgcctc agacgcaaaa cggtgatgta aaacgggtga
     7801 ccgtgatccc gggaagcacg actcaggata tgttgcaaat ggcgattcag aaagcgaagg
     7861 ggtgatattc gctcagagga gaacgcacag gagtgaaagt aaaatgaagt ctatgcgttg
     7921 cgtcataccg gtgattttac tttcctttat cgttcatgaa gggacagcga aaccgaccgc
     7981 tcagattcat tttatgggat cggttgttga ggcaggctgc tggaatgacg tgggaacctt
     8041 agaaattcaa tgctataata aagagggagt tgaacgttat attattgtcg agaatattat
     8101 cacgccgata tcgtctcctc atgcaacggt aaaacgagat tatttggatg aagataagca
     8161 attaacagtg ctacgcattg tctatgactg aaccgcgtag cagaccgcag gtggtgtccc
     8221 gtcagtgtcg tgtgaggata ttatgaaaaa tgttctcacc ttcccggga
//
LOCUS       DAJVBX010000199         8224 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.199, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000199 DAJVBX010000000
VERSION     DAJVBX010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 8224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8224
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.199"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..331
                     /locus_tag="OPV72_003815"
     CDS             <1..331
                     /locus_tag="OPV72_003815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCR9915993.1"
                     /translation="ELMDEPLIVSKGRYELSIMALFKEKGIEPIFKYEFNHPDTALNF
                     IRQGLGIALLPELTLKATTGKLCSVALEPTFYRQISLLAKEPPVEGSPLFLLQKCMET
                     LTDEGLL"
     gene            complement(447..1517)
                     /gene="glpQ"
                     /locus_tag="OPV72_003816"
     CDS             complement(447..1517)
                     /gene="glpQ"
                     /locus_tag="OPV72_003816"
                     /EC_number="3.1.4.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HCR9915994.1"
                     /translation="MKTTLKNLSVALMLAGMTIGSGAVAAEKVVIAHRGASGYLPEHT
                     LPAKAMAYAQGADYLEQDLVMTKDDHLVVLHDHYLDRVTDVADRFPDRARKDGRYYAI
                     DFTLDEIKSLKFTEGFDIENGKKVQTYPGRFPMGKSDFRIHTFEEEIEFVQGLNHSTG
                     KNIGIYPEIKAPWFHHQEGKDIAAKTLEVLKKYGYIGKQDNVYLQCFDVAELKRIKNE
                     LEPKMGMDLNLVQLIAYTDWNETQQKQPDGRWVNYNYDWMFKPGAMKQVAEYADGIGP
                     DYHMLVAEGSTKGNIKLTGMVQDAHQNKMVVHPYTVRADQLPDYATDVNQLYDILYNK
                     AGVDGLFTDFPDKAVMFLQKND"
     gene            complement(1522..2880)
                     /gene="glpT"
                     /locus_tag="OPV72_003817"
     CDS             complement(1522..2880)
                     /gene="glpT"
                     /locus_tag="OPV72_003817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate transporter"
                     /protein_id="HCR9915995.1"
                     /translation="MLSIFKPALHKARLPAAEIDPTYRRLRWQIFLGIFFGYAAYYLV
                     RKNFALAMPYLVEQGFSRGDLGFALSGISIAYGFSKFIMGSVSDRSNPRVFLPAGLIL
                     AAAVMLFMGFVPWATSSIAVMFVLLFLCGWFQGMGWPSCGRTMVHWWSQKERGGIVSV
                     WNCAHNVGGGIPPLLFLLGMAWFNDWKAALYMPAFGAIVVALFAFAMMRDTPQSCGLP
                     PIEEYKNDYPDDYNEKAEEELTAKQIFMQYVLPNKLLWYIAIANVFVYLLRYGILDWS
                     PTYLKEVKHFALDKSSWAYFLYEYAGIPGTLLCGWMSDKVFRGNRGASGVFFMTLVTI
                     ATIVYWMNPAGNPNVDMACMIIIGFLIYGPVMLIGLHALELAPKKAAGTAAGFTGLFG
                     YLGGSVAASAIVGYTVDFFGWDGGFMVMIGGSILAVILLVVVMIGEKRHHDELQLKRN
                     GG"
     gene            3113..4741
                     /gene="glpA"
                     /locus_tag="OPV72_003818"
     CDS             3113..4741
                     /gene="glpA"
                     /locus_tag="OPV72_003818"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic glycerol-3-phosphate dehydrogenase
                     subunit A"
                     /protein_id="HCR9915996.1"
                     /translation="MKTRDSQASDVIIIGGGATGAGIARDCALRGLRVILVERHDIAT
                     GATGRNHGLLHSGARYAVTDAESARECISENQILKRIARHCVEPTDGLFITLPEDGLA
                     FQATFIRACEAAGIRAEAIDPQQARIIEPSVNPALIGAVKVPDGTVDPFRLTAANMLD
                     AREHGAIVLTAHEVTGLIREGATVCGVHVRNHLTGETQTLHAPVVVNAAGIWGQRIAE
                     YADLSIRMFPAKGSLLIMDHRINQHVINRCRKPSDADILVPGDTISLIGTTSTHIDYN
                     EIDSNRVTADEVDILLREGEKLAPVMAKTRILRAYSGVRPLVASDDDPSGRNVSRGIV
                     LFDHAERDGLDGFITITGGKLMTYRLMAEWATDAVCRKLGNTRPCITADTPLPGSKES
                     TEHTLKRIISLPAPLRGSAVYRHGDRTPGWLSEGRQHRSLVCECEAVTAGEVQYAVEN
                     LTVNSLLDLRRRTRVGMGTCQGELCACRAAGLLQRFNVTTAAQSITQLSEFLNERWKG
                     VQPVAWGDALRESEFTRWVYQGLCGLEKEHQDEI"
     gene            4731..5990
                     /gene="glpB"
                     /locus_tag="OPV72_003819"
     CDS             4731..5990
                     /gene="glpB"
                     /locus_tag="OPV72_003819"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate dehydrogenase subunit GlpB"
                     /protein_id="HCR9915997.1"
                     /translation="MKFDTVIMGGGLAGLLCGLQLQQHGLRCAIVTRGQSALHFSSGS
                     LDLLSALPNGQPVTDITAGLDALRRQAPEHPYSRLGAQKVLTLAQQAQTLLNASGAQL
                     YGDVQQAHQRVTPLGTLRSTWLSSPEVPVWPLSAQRICVVGVSGLLDFQAHLAAASLR
                     QRDLNVETAEIDLPELDVLRDNPTEFRAVNIARLLDNEEKWQLLYDALSPIATNCDMI
                     IMPACFGLANDTLWRWLNERLPCALTLLPTLPPSVLGIRLHNQLQRQFVRQGGIWMPG
                     DEVKKVTCRRGTVSEIWTRNHADIPLRPRFAVLASGSFFSSGLVAEREGIREPILGLD
                     VQQTATRAEWYQQHFFDPQPWQQFGVVTDDAFRPSLAGNTVENLYAIGSVLAGFDPIA
                     EGCGGGVCAVSALQAAHHIAERAGEQQ"
     gene            5987..7177
                     /gene="glpC"
                     /locus_tag="OPV72_003820"
     CDS             5987..7177
                     /gene="glpC"
                     /locus_tag="OPV72_003820"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic glycerol-3-phosphate dehydrogenase
                     subunit C"
                     /protein_id="HCR9915998.1"
                     /translation="MSDTRFESCIKCTVCTTACPVSRVNPGYPGPKQAGPDGERLRLK
                     DGALYDEALKYCINCKRCEVACPSDVKIGDIIQRARAKYDTTRPSLRNFILSHTDLMG
                     SVSTPFAPVVNTATALKPVRQLLDYALKIDHRRTLPKYSFGTFRRWYRSVAAQQAKYK
                     DQVAFFHGCFVNYNHPQLGKDLIKVLNAMGTGVQLLSKEKCCGVPLIANGFTDKARKQ
                     AISNVESLREAIAVKGIPVIATSSTCTFALRDEYPEVLDVDNAGLREHIELATRWLWR
                     KLDAGKTLPLNPLPLKVVYHTPCHMEKMGWTLYTLELLRQIPGLELTVLDSQCCGIAG
                     TYGFKKENYPTSQSIGAPLFRQIEESGADIVVTDCETCKWQIEMSTSKRCEYPITLLA
                     KALG"
     gene            7603..>8224
                     /gene="sseL"
                     /locus_tag="OPV72_003821"
     CDS             7603..>8224
                     /gene="sseL"
                     /locus_tag="OPV72_003821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system effector
                     deubiquitinase SseL"
                     /protein_id="HCR9915999.1"
                     /translation="MNICVNSLYRLSTPQFHSLYSEEVSDEALALLFSAVENGDQNCI
                     DLLCNLALRNDNLGHRVEKFLFDLFSGKRSGSPDIDKKINQACLVLHQIANNDITKDN
                     TEWKKLHAPSRLLYMAGSATTDLSKKIGIAHKIMGDQFAQTDQEQVGVENLWCSARML
                     SSDELAAATLGLVQESPLLSVNYPIGLIHPTTKENILRTQLLEKMAQ"
BASE COUNT         2021 a         2225 c         2087 g         1891 t
ORIGIN      
        1 agaactgatg gacgaaccac ttattgtcag taaaggtcgt tatgaattaa gtattatggc
       61 gttgtttaaa gaaaagggta ttgaaccgat atttaaatat gaatttaacc atcccgatac
      121 tgcgctgaat tttattcgcc agggattagg tatcgcctta ttgccagaat taaccttaaa
      181 agccacgaca ggaaaattat gctccgtggc gctggaaccc accttttatc gacaaatttc
      241 actgttagca aaagaaccgc cggtagaagg aagcccgcta tttttattac aaaaatgtat
      301 ggaaacactg accgatgagg gtttgctata aaacaacacc gcctgatgac attgcgttta
      361 tcagacttac gctggcaaac gttgcgccag gccggatgag gcgtttatgt cctcatccgg
      421 cgcttcactt ctactatggc atacctttag tcattttttt gcagaaacat gaccgcctta
      481 tccgggaagt cggtgaacag cccgtcgacg cccgccttgt tatacaggat atcgtataac
      541 tgattgacgt ctgtggcata gtccggcaat tgatcggcac gcacagtgta aggatgcact
      601 accatcttat tctgatgcgc gtcctgcacc attccagtca gcttgatatt ccctttcgtc
      661 gaaccttccg cgaccaacat gtggtaatcc ggaccaatac cgtccgcata ttccgccacc
      721 tgcttcatag cgcccggctt aaacatccag tcgtagttgt aatttaccca acgaccgtcc
      781 ggctgtttct gctgggtttc attccagtcg gtatacgcaa taagttgaac cagattgaga
      841 tccatcccca ttttgggttc cagttcattc ttaatacgtt tcagctcagc gacatcaaaa
      901 cactgcaaat agacattgtc ctgcttgccg atgtaaccat acttcttcag cacttccagc
      961 gttttcgcgg caatatcttt cccttcctga tgatggaacc acggtgcttt aatttccgga
     1021 taaataccga tatttttacc ggtagagtga tttaatccct gaacgaattc aatttcctct
     1081 tcaaaggtat gaatgcggaa atcagatttt cccatcggga aacggcccgg ataagtttgt
     1141 acttttttgc cgttttcaat atcaaaccct tcggtaaact tcagggattt aatttcatcc
     1201 agcgtaaaat cgatagcgta atagcgccca tctttacgcg cccggtccgg aaaacgatca
     1261 gcgacgtcag tcacccggtc aaggtagtgg tcatggagga cgaccagatg gtcgtccttt
     1321 gtcatcacta aatcctgttc cagataatct gccccttgcg catacgccat cgctttcgcc
     1381 ggtagcgtat gctccggcag ataaccgctg gcgccacggt gggcgatgac gactttttca
     1441 gccgccacgg cgccgcttcc gatggtcatt cctgccaaca tcaacgccac gctaaggttt
     1501 ttcagtgtgg ttttcatgtt attagcctcc gttgcgtttt aactgcagct catcatgatg
     1561 gcgtttttcg ccaatcatca cgaccaccag caggattacc gccagaatgc taccgccaat
     1621 catcaccata aagccgccat cccaaccgaa gaagtcaacg gtataaccca caatggcgct
     1681 tgcagcgaca gaaccgccca ggtaaccaaa cagaccggta aagcccgccg ccgtacccgc
     1741 cgcttttttc ggcgccagct ccagcgcgtg cagaccgatc aacattaccg ggccgtagat
     1801 caggaagccg atgataatca tacaagccat atcaacgttc gggttgcctg ccgggttcat
     1861 ccagtaaacg atggtcgcga tagtgaccag ggtcataaag aatacgcccg acgcgccacg
     1921 gttgccgcgg aagactttat ccgacatcca gccacacagc agcgtgcctg gaatacccgc
     1981 gtattcatag aggaagtagg cccaggagga tttatcgagt gcgaaatgct tcacttcttt
     2041 caggtaggtc ggtgaccagt cgaggatacc gtagcgcagc aggtagacga acacgttggc
     2101 gatagcgata taccacagta atttgttcgg cagtacgtac tgcatgaaga tctgcttcgc
     2161 agtcagctct tcttccgctt tttcgttgta gtcatccgga tagtcgtttt tatactcttc
     2221 gataggcggc agaccgcagg attgcggcgt atcgcgcatc attgcgaaag cgaacagtgc
     2281 caccacaatc gcgccaaagg ctggcatata gagcgccgct ttccagtcgt taaaccacgc
     2341 catccccagc aggaacagca gtggcgggat cccgccgccg acgttatgcg cacagttcca
     2401 gaccgacaca atgccgccgc gctctttctg cgaccaccag tgaaccatcg tacgtccgca
     2461 cgacggccac cccatcccct ggaaccagcc gcaaaggaac aacagcacaa acatcacggc
     2521 gatgctggat gtcgcccacg gcacaaagcc cataaacaac atgactgctg cggccagaat
     2581 caaccctgcc ggcagaaaaa cgcgcggatt cgagcgatcg gacaccgaac ccattataaa
     2641 tttcgaaaaa ccataagcga tagaaatccc ggacagcgca aagcccagat cgccgcgtga
     2701 aaaaccctgt tctaccaggt agggcatcgc gagggcaaag ttcttgcgca ccagataata
     2761 cgcggcatag ccaaagaata tccccaggaa aatctgccag cgtaatcggc gataggtcgg
     2821 atcaatctcc gccgctggca agcgcgcttt atgaagcgct ggtttaaaaa tactcaacat
     2881 attgtagcct ccgtagcccg tattttattt agaggtaaac accgcagttc gttcaaacaa
     2941 ccccgctgct cccagtgtgg ccgcgatgtt aagtaaagat acgtcacgtt aatgtgaatt
     3001 acagcacata ttgttacagt tttatgacta atgttcagaa aggcgcgcga aatcaaacat
     3061 tccatatgat ttgtatggct aaatgataaa aaacgaactg taaggaaaaa caatgaaaac
     3121 tcgcgactcg caagcaagtg acgtgattat cattggcggt ggagcaacag gcgcagggat
     3181 cgcccgcgac tgcgcgctgc gcggtttacg tgtcattctg gtggagcggc atgatatagc
     3241 gaccggcgcg accgggcgta accacgggct gctgcacagc ggcgctcgtt atgcggttac
     3301 cgacgcggaa tccgcgcgcg agtgcattag tgaaaaccag attttaaaac ggatcgcccg
     3361 ccattgcgtc gaaccgacgg atggtctgtt tattacgttg ccggaagatg gtcttgcgtt
     3421 tcaggccacc tttattcgcg cctgtgaagc ggcaggcatt cgcgctgaag ccatcgatcc
     3481 gcagcaggct cgcatcatcg aaccttccgt taaccctgcg ctcatcggtg cggtaaaagt
     3541 gccggatggc accgtagacc ctttccgcct gaccgccgcc aatatgctgg atgccagaga
     3601 acatggcgca atcgtgttaa cggcgcatga agtgaccggg ctcattcgtg aaggcgcaac
     3661 ggtctgcggc gtccatgtgc gtaaccatct cactggcgaa acccagacgc ttcacgcgcc
     3721 ggtggtggtc aatgcggctg gtatctgggg gcaacggatc gccgaatacg ccgacctgag
     3781 tattcgcatg ttcccggcga aaggctcgct gttgatcatg gaccatcgga tcaaccagca
     3841 tgtcattaac cgctgccgga aaccatcgga tgccgacatt ctggtacctg gcgatacgat
     3901 ttcactgatc ggcaccacct ctacccatat tgattacaat gagatagaca gcaaccgcgt
     3961 caccgcagat gaagtcgata tcctgctgcg tgaaggggaa aaactggccc ctgtcatggc
     4021 gaagacacgt attctgcgcg cgtattccgg cgtccgcccg ctggtggcca gcgatgacga
     4081 tcccagcggt cgtaacgtca gccgcggtat tgtgttgttc gaccacgccg aacgcgacgg
     4141 gcttgatggc ttcattacca ttaccggcgg gaagctaatg acttatcgcc tgatggcgga
     4201 atgggcgacc gacgccgtgt gccgcaagtt gggcaatact cgcccctgca tcacggcgga
     4261 tacgccgttg cctggctcaa aagagtctac ggaacatacg ctgaaacgca ttatctcgct
     4321 tcccgcgccg ctacgcggat cggcggttta tcggcatggc gatcgcacgc cggggtggct
     4381 gagtgaaggc cgccaacacc gtagcctggt ctgtgaatgc gaggccgtca cggcggggga
     4441 agtgcagtat gccgtcgaaa acttaaccgt gaatagcctg ctggatctgc gccgtcgcac
     4501 ccgcgtaggg atgggcactt gccagggcga actgtgcgcc tgccgcgcgg ccgggctatt
     4561 gcagcgtttt aatgtgacga ccgcggcgca atctattacg caactctctg aatttctgaa
     4621 tgagcgctgg aaaggcgtac aacctgtcgc ctggggagac gcgctgcgcg aaagcgaatt
     4681 cacgcgctgg gtttatcagg gattatgcgg tctggagaag gagcaccagg atgaaatttg
     4741 atacggttat tatgggcggc ggtctcgccg gtttgctatg cggactgcaa ctccagcagc
     4801 atggattacg ctgcgccatc gtcacccgcg gacaaagcgc gctgcatttt tcctccggct
     4861 cgctggatct acttagcgcc ctgcccaacg gccaaccggt gaccgacatt accgccgggc
     4921 ttgatgcgct gcgccgccag gcgcctgaac atccttattc gcgtttaggc gcgcaaaaag
     4981 tccttacgct ggcgcaacag gcgcaaacgc tacttaacgc cagcggcgcg cagttatacg
     5041 gcgacgtaca gcaggcgcac cagcgtgtca cgccgcttgg cacattgcgt tctacctggc
     5101 ttagctcgcc ggaagtaccg gtctggccgt tatccgcaca gcgaatttgc gtcgtcggcg
     5161 ttagcggatt actggatttc caggcgcacc ttgcggcagc gtcgctgcgc caacgcgacc
     5221 tcaacgttga aaccgcagaa atcgaccttc cggaactgga cgtactgcgt gataacccga
     5281 cggaatttcg cgcggtcaat atcgcgcgtc tgcttgataa cgaagaaaaa tggcagctgc
     5341 tgtacgacgc gctgtcgcca atagcgacaa actgcgacat gatcatcatg cccgcctgtt
     5401 tcgggctggc gaacgatacg ctgtggcgct ggcttaacga acgtctgccc tgcgcgctca
     5461 cgctgctgcc gacgctgccg ccatcggtgc tcggtattcg tctgcacaat caactccagc
     5521 gccagtttgt ccgtcagggc ggcatctgga tgccgggcga tgaagtgaag aaagtcacct
     5581 gccgtcgcgg taccgtgagc gaaatatgga cccgcaacca tgccgatatt ccactgcgcc
     5641 cgcgttttgc cgtacttgcc agcggtagct tctttagtag cgggctggtt gccgagcgcg
     5701 aagggatccg cgaacctatt ttagggctcg acgtacagca aacggccacc cgcgccgaat
     5761 ggtatcaaca acatttcttc gacccacagc cctggcagca gtttggcgtc gtgacggatg
     5821 acgctttccg cccctccctt gcgggcaaca cggtagaaaa tctgtatgca ataggttctg
     5881 tgctggcggg attcgatcct atagctgagg gatgcggcgg cggcgtctgc gcagtcagcg
     5941 ccctccaggc cgcgcaccat atcgctgagc gtgcaggaga acagcaatga gcgacacacg
     6001 ttttgaaagt tgtattaaat gtacggtgtg caccaccgcg tgcccggtca gccgcgttaa
     6061 tcctggctac cctggcccta aacaggccgg accggatggc gaacgcctgc gtctgaaaga
     6121 cggcgcgctg tatgatgagg cgctgaaata ttgcattaac tgcaaacggt gtgaggtcgc
     6181 ctgtccgtcg gacgtgaaga ttggcgatat catccagcgc gcccgcgcga aatacgatac
     6241 gacgcgcccg tcattgcgta actttattct cagccatacc gatctgatgg gcagcgtttc
     6301 aacgccgttc gcgccggtgg tcaataccgc caccgcatta aagccagtgc gccagttgct
     6361 tgattacgcg ctcaaaatcg atcatcgccg caccttacca aaatactctt tcggcacctt
     6421 ccgccgctgg tatcgtagcg tggcggcgca gcaggctaaa tacaaagatc aggtcgcctt
     6481 tttccatggc tgttttgtga attacaacca tccgcagctc ggaaaagatc tgattaaggt
     6541 gctgaacgca atgggtactg gcgtacagtt actgagtaaa gagaagtgtt gcggcgtacc
     6601 gctgatcgct aacggtttta cggataaagc tcgcaaacag gctatcagca atgtggagtc
     6661 gctacgagag gcgattgccg tcaaaggtat tccggtcatc gccacgtcat ccacctgtac
     6721 gtttgcgttg cgcgatgaat atcctgaagt gctggacgtg gacaacgccg ggctgcgcga
     6781 acatatcgag ctggccaccc gctggctatg gcgcaaactg gatgccggga aaacgctgcc
     6841 gcttaatcct ttgccgctga aagtggtcta ccatacgccg tgtcatatgg aaaaaatggg
     6901 ctggacgctt tacacgcttg aactgttgcg gcaaattccg gggcttgaat tgacggtact
     6961 tgattcacag tgctgcggca ttgccggtac gtatggattt aaaaaggaaa actatccgac
     7021 atcacagtcc atcggcgcgc cgctgttccg ccagattgaa gagagcggcg ccgacattgt
     7081 cgtcaccgat tgtgaaacct gtaagtggca aattgagatg tctacaagca aacgctgcga
     7141 ataccccatt acgctactgg cgaaagcgct gggctaagta aaaagcgccg gagcccctcc
     7201 ggcgccatta ctctactcac cagggccgat tttccatcag acatataccc ttcatacttc
     7261 aagttgctta tgtgttggct acggattatt ttgggtataa acgcggatgt ctctttgcaa
     7321 taacctgccc tatttggtta accatgaccg ctaacccacg gtggcatgac agataacgac
     7381 gttactgttt atagagcaat atctcttgta tcgccgcgtt accagcctcc tttaaagagg
     7441 gggataactg aatatctcca ataataattg agtgttatgt gaataataat aaaatcaggt
     7501 ctatgcctga tttaatatat ctcccactaa caataatatt tttacaaata attatacatg
     7561 acatcatatt cgttactttc acctaccagg aaacagagca aaatgaatat atgtgtaaat
     7621 tcactttacc gattgagcac accgcaattt cacagtttat attcagaaga ggtgagcgat
     7681 gaggcgcttg cgttgttgtt tagcgccgta gagaacggtg atcagaattg tattgatctg
     7741 ttatgcaatc ttgcgttacg caatgataac ctgggacata gagttgagaa atttcttttt
     7801 gatctcttta gcggaaaaag atcgggatca ccagacatag acaaaaaaat caatcaggct
     7861 tgccttgtat tacatcaaat cgccaataac gatataacaa aagataatac tgagtggaaa
     7921 aagctacatg ccccttccag attactttat atggccggtt ccgcgacaac cgacctttct
     7981 aaaaaaatag gaatagcaca taaaattatg ggcgaccagt tcgctcagac agatcaagaa
     8041 caggtaggag ttgaaaatct ttggtgtagt gcgcgaatgt tgtcgtcaga tgagctagca
     8101 gccgcaacgc taggtctggt tcaagaatca cctcttctct cggtaaacta tcctattggg
     8161 cttattcatc ctaccaccaa agaaaatata ttacgcactc agctacttga aaagatggct
     8221 caat
//
LOCUS       DAJVBX010000200         8104 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.200, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000200 DAJVBX010000000
VERSION     DAJVBX010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 8104)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8104)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8104
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.200"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(191..943)
                     /locus_tag="OPV72_003822"
     CDS             complement(191..943)
                     /locus_tag="OPV72_003822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCR9916000.1"
                     /translation="MNSRQQSILQMVVDKGQMSVAELAKITGVSEVTIRQDLNTLEKQ
                     SYLRRAHGFAVSLESDDVETRMMTNYTLKRRLAEFAASLVSPGESVFIENGSSNALLA
                     RTLAEQKDVTIITVSSYIAHLLKETPCEVILLGGIYQKKSESMVGPLTRQFIHQVHFS
                     KAFIGIDGWQADTGFTGRDMMRSDVVNAVLEKGSEAIVLTDSSKFGCVHPYPLGPLSR
                     FHRVITDSKISASDQMQLEHAGLLVNVIGSSV"
     gene            complement(1030..1209)
                     /locus_tag="OPV72_003823"
     CDS             complement(1030..1209)
                     /locus_tag="OPV72_003823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916001.1"
                     /translation="MSDIEAQRIAARIDTVLDILVAGDYHSAINNLEILRAELLDQVK
                     DGISPSQAPGSPWEI"
     gene            complement(1331..3313)
                     /gene="pdeR"
                     /locus_tag="OPV72_003824"
     CDS             complement(1331..3313)
                     /gene="pdeR"
                     /locus_tag="OPV72_003824"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic di-GMP phosphodiesterase"
                     /protein_id="HCR9916002.1"
                     /translation="MMKQIQEQTALNPLHSHWRLADDRNVLYLSPTGETDAEKTVELS
                     PEQAGRIREITAITSSLLITLLIEKQVTAVHLVGRKINNREWAGSLATWPDTPAVAPT
                     QAQELSFAEQIVSEANSVIAILDSRGKICRFNRLCEEYTGLKERDVIGQSVFKLFMSR
                     REAVASRHYIENFFRNGNAYEIERWIKTRKGQRLFLFRNKFVHNGSGKNEIFLICAGT
                     DITEERRAQERLRILANTDTVTGLPNRNAIHEFINHAIASAGESQVGIVYLDLDNFKK
                     INDAYGHMFGDQLLQAVSLALLSCLEEDQLLARLGGDEFIVLVAHTSQAALEAVASRI
                     LTRLRQPFRIGLIEVYTGCAIGISLAPRHGQDSESLIRTADTAMYNAKEGGRGQFCVF
                     SPEMNQRVFDYHWLDTNLRKALENDQLLIHYQPKITWRGEVRSLEALVRWQSPERGLI
                     PPLEFISYAEESGLIVPLGRWVILDVVRQIAKWRDKGINLRVAVNFSARQLADQTLFT
                     ALKQALYDLNFEYCPIDVELTESCLIENDTLALSVIQQFSQLGAQIHLDDFGTGYSSL
                     SQLARFPIDAVKLDQAFVRDIHKQPLSQSLVRAIVAVAQALNLQVIAEGVENAKEDAF
                     LTKNGVNERQGFLFAKPMPAVSFERWYKRYQTKKMR"
     gene            complement(3575..5509)
                     /locus_tag="OPV72_003825"
     CDS             complement(3575..5509)
                     /locus_tag="OPV72_003825"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exoribonuclease II"
                     /protein_id="HCR9916003.1"
                     /translation="MFQDNPLLAQLKQQLHSQTPRAEGVVKATEKGFGFLEVDAQKSY
                     FIPPPQMKKVMHGDRIVAVIHTEKERESAEPEELIEPFLTRFVGKVQGKNDRLSIVPD
                     HPLLKDAIPCRAARGVQHEFKEGDWAVAEMRRHPLKGDRSFYADLTQYITFADDHFVP
                     WWVTLARHNLEKEAPNGVATEMLDEGLERQDLTALNFVTIDSASTEDMDDALYAEELA
                     DGRLQLTVAIADPTAWIAEGSKLDNAAKIRAFTNYLPGFNIPMLPRELSDDLCSLRAN
                     EVRPALACRMIIAADGTIDDDIAFFAATIESKAKLVYDNVSDWLENNSTWQPENEGIA
                     QQIRLLHRICLSRSEWRHHHALVFKDRPDYRFVLGEKGEVLDIVAEPRRIANRIVEES
                     MIAANLCAARVLRDKLGFGIYNVHTGFDPANADALAALLKTHGLHVDAEEVLTLEGFC
                     KLRRELDAQPSGFLDSRIRRFQSFAEISTEPGPHFGLGLEAYATWTSPIRKYGDMINH
                     RLLKAVIKGEAIARPQEDITQQMAERRRLNRMAERDVGDWLYARFLNDKAGTNTRFAA
                     EIIDVSRGGMRVRLVDNGAIAFIPAPFLHAVRDELVCSQENGTVQIKGETVYKVTDVI
                     DVTIAEVRMETRSIIARPAA"
     gene            complement(5811..6731)
                     /locus_tag="OPV72_003826"
     CDS             complement(5811..6731)
                     /locus_tag="OPV72_003826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HCR9916004.1"
                     /translation="MEQCRKAGKSHWYHETQSTMSSQTPLSLMPEAAYVNDRFLLDLA
                     VAETALTPFESWLKPARQLADVLFPRTVLNDRLHTFSAYERMSTALTAAQVFGVQRLC
                     RHYAARLAPLPGPDASRESNQRLAQITQYARQLAGSPSVINTRAREQLAEVGLTARDT
                     VLINQIIGFIGFQARVAAIFQAFCRLPVRELPGQEMQRFARAARFQNPQTTWRPAASL
                     VEYPLAHTKVRRQYSSSQCQIMAPVLMRDPSSFALLERILTSTLHTASPPSLLPLITL
                     LTSRINGSAACFNEQATQPGAWRRAVITLR"
     gene            complement(6931..7719)
                     /gene="fabI"
                     /locus_tag="OPV72_003827"
     CDS             complement(6931..7719)
                     /gene="fabI"
                     /locus_tag="OPV72_003827"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HCR9916005.1"
                     /translation="MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKL
                     KGRVEEFAAQLGSSIVLPCDVAEDASIDAMFAELGNVWPKFDGFVHSIGFAPGDQLDG
                     DYVNAVTREGFKIAHDISSYSFVAMAKACRTMLNPGSALLTLSYLGAERAIPNYNVMG
                     LAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRR
                     TVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMNELELK"
     gene            complement(7837..>8104)
                     /locus_tag="OPV72_003828"
     CDS             complement(7837..>8104)
                     /locus_tag="OPV72_003828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916006.1"
                     /translation="HLDEYSGFLQNLYLSGGRRIAIVLAVRPGVSGWMRRTLHQLVYC
                     TVGPVPLDSLICQFGPGECSKSSGTSLPCGFRTSPAGDSGGKIA"
BASE COUNT         1984 a         2084 c         2110 g         1926 t
ORIGIN      
        1 aagagatttt ccgtaaaacc tgattgcgca ggggtatatc acgcaggtga tagtcacttc
       61 ctgttatttc gctaatatta attttacgac gttacgctcg ttacaacagg taaatagtct
      121 taattgggat gtcagaaaag tcttagagag aggatgattt gccatagagg gcaaaccatc
      181 gggaaatatt ttaaacggat gagccaataa cattgactag cagccctgca tgctctaact
      241 gcatttgatc gctggcggaa attttggaat ccgtaatgac acgatggaag cgagagagcg
      301 ggcccagggg atagggatgc acacagccaa atttggagct gtcggtgagg acaatcgctt
      361 ctgagccttt ttccagaaca gcgttaacca catccgatcg catcatatcg cgtccggtaa
      421 agccggtatc agcctgccag ccatcaatac cgataaatgc tttgctgaaa tgcacttgat
      481 ggataaactg tcgcgtcaac ggccctacca tgctttcact ttttttctga tagattccac
      541 cgaggagaat gacttcgcaa ggggtttctt tgagcagatg cgcgatataa ctgctcacgg
      601 tgatgatcgt gacatctttt tgttccgcca gcgtccgggc caatagcgca ttgctactgc
      661 cattttcaat aaaaacggat tccccaggac tgaccagcga ggcggcgaac tccgccagtc
      721 ggcgttttag cgtgtagttc gtcatcatgc gagtctctac gtcatcgctc tcaagcgaaa
      781 cggcgaaacc gtgcgcacgg cgtaaatagc tctgtttttc cagggtattc agatcctgac
      841 gaatcgtgac ttcagatacg ccggtaattt tcgccagttc agcaacgctc atctggcctt
      901 tatcaaccac catttgcaaa attgattgtt gtcgggagtt catagtatta attttattcg
      961 ttaagaggag tcaacagaca gtcagagagc cgggaagggc taacggccat cccggacaaa
     1021 taatcgctat cagatttccc agggcgaccc gggagcctgg gatggcgaga taccgtcttt
     1081 aacctgatct aacagctctg ctctcaatat ttcaaggtta ttgatggccg agtggtaatc
     1141 gccagcaaca aggatatcca gcacggtatc aatgcgtgcg gcaattcgtt gtgcttcgat
     1201 atcagacatg tttgtcatcc ttaatgtcag aaaaggtttc aattcatgat gcagaaatta
     1261 atctgaaaag agaagggaaa aatagggcta tgcctgtctg cacaggctgt tctccctatt
     1321 atcgccgcca ttaacgcatt tttttcgtct gataacgttt gtaccagcgt tcaaaagaaa
     1381 cggcgggcat aggtttggcg aataaaaagc cctgtcgttc attgacgccg ttttttgtca
     1441 ggaaggcatc ttctttagca ttttccacgc cttcggcaat cacttgtaaa tttagcgcct
     1501 gagccaccgc gacaatcgcc cgaaccagag attgcgacag cggttgctta tggatatctc
     1561 tgacgaaagc ctgatccagt ttaacggcat caatagggaa ccgggcgagt tgagaaagcg
     1621 aagaataccc tgtgccaaaa tcatccagat gaatctgggc gccgagctga ctaaattgct
     1681 ggataaccga tagcgccagc gtgtcgtttt cgatcaggca gctttccgtt agctcgacat
     1741 cgattgggca atactcaaaa ttcagatcgt acaaagcctg tttaagcgca gtaaaaagcg
     1801 tctggtcggc cagttgtcgc gccgaaaagt taacggctac gcgcaagtta atccccttat
     1861 cgcgccattt cgcaatctgg cgaactacat ccagaatcac ccagcggccc agcgggacga
     1921 tgagtcctga ctcttcggcg tatgagatga actccagcgg cggaattaat ccgcgttccg
     1981 gcgattgcca gcgtaccagc gcttccaggc tacgtacttc gccgcgccag gtaattttgg
     2041 gctgatagtg aataagtaac tggtcgtttt ccagcgcttt tcgcaggttt gtatccagcc
     2101 agtgatagtc aaatacgcgc tgattcattt ccggcgaaaa aacgcagaac tgaccgcggc
     2161 cgccttcttt ggcgttatac attgcggtgt cggcagtgcg aatgagactt tcgctgtcct
     2221 gtccgtgccg gggggccaac gaaatgccaa tggcgcatcc cgtgtaaact tcaatgagtc
     2281 caatgcgaaa cggttgccgc agccgggtaa ggattcgtga ggctactgct tccagcgcgg
     2341 cctgagacgt atgggcaacg aggacaatga attcatctcc ccccagtctg gccagcaatt
     2401 gatcttcctc cagacaactc aacagcgcca gtgaaacggc ctgtaagagc tgatcgccaa
     2461 acatatgccc ataggcgtca ttaattttct tgaagttatc cagatcgaga taaacgatac
     2521 ccacctgcga ctcgccagcc gaggcaatag catgattaat aaattcatga atagcattgc
     2581 gattgggcag gccggtgacg gtgtctgtat tcgccagtat gcgtaaacgc tcctgagccc
     2641 gcctttcttc ggtgatatcc gtgcctgcgc agatcagaaa gatttcgttt tttccgctac
     2701 cgttatggac gaatttatta cgaaataaga acagacgttg gcctttacga gtctttatcc
     2761 agcgttcgat ttcataggca ttgccattgc gaaaaaaatt ctcaatgtag tgtcgggagg
     2821 caaccgcctc ccggcgactc ataaataatt taaatacgct ttgaccaatt acatctcgct
     2881 cttttaagcc cgtgtactct tcgcataacc gattaaatcg acagattttt ccccgactat
     2941 ccagtatcgc aatgactgag ttggcttctg atacgatttg ctcggcaaaa gagagttcct
     3001 gcgcctgcgt tggcgcgacg gcaggcgtat caggccaggt tgccaggctg ccagcccatt
     3061 cacggttatt aatcttacgg cctaccaggt gcacagcggt aacctgtttt tctatcaaca
     3121 acgttatcag cagactggac gtaatcgccg ttatttcccg gatacgcccg gcttgctccg
     3181 gcgatagctc aaccgttttt tctgcatccg tttcacctgt cggggagaga tacagcacgt
     3241 tgcggtcatc agccagacgc cagtgagagt gaaggggatt tagcgccgtt tgttcctgaa
     3301 tctgtttcat catgcgtacc atcccattta agcgccaggt gcccgaaaag aaaggttagc
     3361 catgttataa ataagggtaa ttatggctga acatattgtt ttatctatgt attcatatgt
     3421 aatccagatt ctggaaaaag catagtcgcc agctaaaaat aacaagaaat ggggcgcttg
     3481 aataagatta aacttagagc atgacggaag ggagaagaag aaaagaaacg gcctttgcct
     3541 tctcagcaaa ggccgttgag cgagctaagc gtggttacgc tgccggtcgg gcaataatgc
     3601 tgcgggtttc catgcgaact tccgcaatag tgacatcaat gacatccgtc actttataaa
     3661 ccgtctcacc tttaatctgt accgtaccgt tttcctggct gcataccagt tcatcgcgaa
     3721 cggcgtgcag gaacggggca gggataaagg cgatagcgcc gttatcgacc agtcgcacac
     3781 gcataccacc gcggctgacg tcaataattt ctgccgcgaa acgggtattt gtccccgcct
     3841 tatcgttaag gaagcgtgca tataaccagt cgccgacatc gcgctccgcc atgcggttca
     3901 ggcgacggcg ttccgccatt tgctgggtga tatcttcctg cggacgcgca atagcttccc
     3961 ccttgatgac cgctttcagc aggcgatggt taatcatatc gccatactta cggatgggag
     4021 aggtccaggt ggcataagcc tcaagaccaa gaccgaaatg cggccccggc tcggtgctga
     4081 tttccgcaaa agactggaag cgacgaatgc ggctgtcaag gaaaccggag ggctgcgcat
     4141 ccagttcgcg acgcagttta cagaagcctt ccagcgtcag cacctcttcg gcatcgacat
     4201 gcagaccatg cgttttcagc agcgcggcca gcgcgtcggc attcgcggga tcgaagcccg
     4261 tatgtacgtt gtaaataccg aaaccgagct tatcgcgcag tacgcgcgcg gcgcaaaggt
     4321 tagcggcgat catcgactct tctacgatac ggttagcgat acggcgcggt tccgccacaa
     4381 tatccagtac ttcgcctttt tcgccaagca caaagcggta atccgggcgg tctttaaaga
     4441 ctaacgcatg atgatgacgc cactcactgc ggcttagaca aatacggtgc aacagacgaa
     4501 tctgctgggc aatgccttcg ttctccggct gccaggtgct gttattttcc agccagtcgg
     4561 agacattgtc gtacaccagc ttggccttcg attcgatggt ggccgcaaaa aaggcaatat
     4621 catcgtcaat ggtgccgtcc gcggcgatga tcatgcgaca ggcgagcgcc ggacgcactt
     4681 cgttggcgcg cagcgaacac agatcgtcag acagctcacg tggcagcata ggaatattga
     4741 agcccggcag gtagttggtg aaggcgcgaa ttttcgcggc gttatccagc ttactgcctt
     4801 cggcaatcca ggcggtagga tcggcgatag ccaccgtaag ctggagtctg ccgtccgcta
     4861 attcctcagc ataaagcgcg tcatccatat cttcagtgct ggcgctatcg atagtgacga
     4921 aattcagcgc ggtaagatcc tggcgctcca gcccttcgtc cagcatctcc gtcgctacgc
     4981 cgttcggcgc ttctttttcc aggttatggc gggcaagcgt aacccaccag ggaacaaagt
     5041 gatcgtcggc aaaggtgatg tactgcgtta aatcggcgta aaacgaacgg tcgcctttaa
     5101 gcggatggcg gcgcatttcg gcaaccgccc agtcaccttc tttgaactca tgctgaacgc
     5161 cgcgcgcggc gcggcaggga atcgcgtctt tcagcaacgg atgatctggc acgatggaca
     5221 ggcggtcatt tttaccctga acttttccca caaagcgcgt caggaacggt tcgatcagtt
     5281 cttccggctc ggcagactca cgttcttttt ccgtgtggat gaccgcgacg atacgatcgc
     5341 catgcatcac ttttttcatc tgcggcggag gaatgaagta gcttttttgc gcgtcaacct
     5401 caaggaagcc aaagcctttt tccgtggctt ttacgacccc ttcagcgcgc ggcgtctggg
     5461 aatgcagttg ctgtttaagc tgcgctagca gcgggttgtc ctgaaacata ttcgtctatt
     5521 ttcgtagcca aaagagcggc tgacagtttt acgcgattct gcctggcgca gcaagcgctc
     5581 tttcagtaat ggatgagtta ataggtttcg cccaacgcga tttttaaacg atttaaccat
     5641 ccgcacacgc cacaccagcc taacatatta atggcctgct ccgatgaaac tcccctggtg
     5701 agtagcggga aaaaatgcgc ggcgctaaag cgatcgggcg ctctggtgag ccattgtatc
     5761 gcctgtgtca gcgcgggctc aagttcccaa cgagcgatgt cgtcgtcttc ctagcgtaac
     5821 gtgatgacag cacggcgcca cgcgccaggt tgggttgcct gttcgttaaa gcaggcggcg
     5881 ctgccgttga tacgtgatgt gaggagcgtg ataagtggaa gtaaagaagg gggcgacgca
     5941 gtgtgtaatg tgctggtcag tatgcgttcg agtaacgcga atgaagacgg atcgcgcatg
     6001 agtaccggcg ccattatttg gcattgtgaa gacgaatatt gccgccgaac tttggtatgg
     6061 gcgagaggat attctaccag actggcggcg ggccgccatg tcgtctgggg gttttgaaac
     6121 cgcgcggccc tggcaaagcg ctgcatctcc tggccgggca gctcgcgcac gggcagacgg
     6181 caaaacgcct gaaatatcgc cgctactcgc gcctgaaaac cgataaaccc aatgatctga
     6241 ttgatgagta cggtatcccg ggcggttaat cccacctctg caagctgttc gcgggctcgc
     6301 gtattgataa cggaggggga gccggcaagc tgacgagcgt attgcgtaat ttgcgccagc
     6361 cgttgattgc tttctcttga ggcgtcaggg ccgggtagcg gcgccagacg tgcggcataa
     6421 tggcggcaca aacgctgaac cccaaatacc tgagcggcgg taagggcggt gctcatacgt
     6481 tcataggcgc taaacgtatg aagccggtcg ttgagaaccg tgcggggaaa taagacatcc
     6541 gccaactggc gagctggctt taaccatgac tcaaaaggcg tcaacgcggt ttctgctacc
     6601 gctaaatcca gtaaaaatcg atcgttaaca tacgcggctt ccggcatcag cgaaagcgga
     6661 gtttgtgacg acatagtgga ttgtgtttca tgataccagt ggcttttacc cgcttttcgg
     6721 cattgttcca tagggtttcc cgaggatgaa atggcgatcg ataatgattc agcgtcggat
     6781 cgtttatgct ggattatcct ggcgtatgcg ggaaagggat gaaagattgt taggtgataa
     6841 caaatatcag aacgctatat aacgagatga gcggtgagtg aggggaatgg ggcagcacag
     6901 ccgtgccgcc cgctaataaa cttaatgcgc ttacttcagt tccagttcat tcattgccgc
     6961 aatgctgaac ccgccgtcaa catggacgac ttcgccagaa atgcctgccg agagatcgga
     7021 acacagaaac gccgctgagt tacccacatc ttcaatggtc acggtgcgac gaattggcgt
     7081 aacggcttca caatgcgcca gcattttacg gaagtcttta ataccggacg ccgccagcgt
     7141 gcggatcggg cccgcagaga tggcgttgac gcgaacccct tccggtccca tagcgtttgc
     7201 catataacgc acgttggctt ccagagaggc tttcgccaga cccatgacat tgtagttcgg
     7261 gatggcgcgc tccgctccca gataagacaa ggtcaacagc gcagaacccg gattcagcat
     7321 ggtgcggcag gctttcgcca tggcaacaaa actgtaagag ctaatatcgt gagcgatttt
     7381 aaagccttcg cgggtaaccg cattaacata atcgccgtcc agctgatcgc caggcgcgaa
     7441 accgatcgag tgaacgaaac cgtcaaattt cggccaaacg ttacccagct ccgcaaacat
     7501 agcgtcaatg ctggcatctt cagcgacatc acacggtaaa acgatgctgg aacccagctg
     7561 ggcagcaaat tcttctacgc ggcctttcag tttgtcgttc tggtaggtga acgccagttc
     7621 agctccttcg cggtgcatcg cctgtgcgat accgtaggcg atggacagtt tactggccac
     7681 gccagtgacc agaatgcgct taccggaaag aaaacccata gctttaatcc ttatagtcat
     7741 tgcttatttt ttgcttttac gaacaatggt taacagcaac ttttcaacat tattcgaaat
     7801 tagtctgaaa ttatatccca ctcctggccc cgtgtgtcac gctatttttc cgccgctatc
     7861 tccggcaggt gacgttctaa aaccacacgg taacgaagtc cctgaggatt ttgagcactc
     7921 cccagggcca aactggcaaa tcaaagagtc taatgggaca ggccctacgg tgcagtatac
     7981 cagctggtgt aaggttcgcc tcatccaacc agagacaccg ggacggacag caagtacgat
     8041 agcgatgcgc cttccaccag acaaataaag gttctgtagg aagcctgaat attcatccaa
     8101 atgg
//
LOCUS       DAJVBX010000201         7848 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.201, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000201 DAJVBX010000000
VERSION     DAJVBX010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 7848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7848
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.201"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(30..383)
                     /locus_tag="OPV72_003829"
     CDS             complement(30..383)
                     /locus_tag="OPV72_003829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916007.1"
                     /translation="MADAFILLGIVMAMVSLGFILINKLFCFISAGCLLSLCASMASL
                     QLWDASYWGRWGKVCPGLDVIISCDNYHSLYDLGWGLYGIAFLFFTALMLTCVVIILI
                     NMIMALERYCAGWRR"
     gene            complement(491..3037)
                     /gene="cyaA"
                     /locus_tag="OPV72_003830"
     CDS             complement(491..3037)
                     /gene="cyaA"
                     /locus_tag="OPV72_003830"
                     /EC_number="4.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I adenylate cyclase"
                     /protein_id="HCR9916008.1"
                     /translation="MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHY
                     HHPLMPGYLDGNVPSGICFYTPDETQRHYLNELELYRGMTPQDPPKGELPITGVYTMG
                     STSSVGQSCSSDLDIWVCHQSWLDGEERQLLQRKCSLLESWAASLGVEVSFFLIDENR
                     FRHNESGSLGGEDCGSTQHILLLDEFYRTAVRLAGKRILWSMVPCDEEEHYDDYVMTL
                     YAQGVLTPNEWLDLGGLSSLSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYP
                     NPRLLAKDIKQRLHDGEIVSFGLDPYCMMLERVTEYLTAIEDPTRLDLVRRCFYLKVC
                     EKLSRERACVGWRREVLSQLVSEWGWDDARLTMLDNRANWKIDQVREAHNELLDAMMQ
                     SYRNLIRFARRNNLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLT
                     FIHVPPGRANRSGWYLYNRAPNMDSIISHQPLEYNRYLNKLVAWAWFNGLLTSRTHLF
                     IKGNGIVDLPKLQEMVADVSHHFPLRLPAPTPKALYSPCEIRHLAIIVNLEYDPTAAF
                     RNKVVHFDFRKLDVFSFGEEQNCLIGSIDLLYRNSWNEVRTLHFNGEQAMIEALKTIL
                     GKMHQDAAPPDSVEVFCYSQHLRGLIRTRVQQLVSECIELRLSSTRQETGRFKALRVS
                     GQTWGLFFERLNVSVQKLENAIEFYGAISHNKLHGLSVQVETNQVKLPSVVDGFASEG
                     IIQFFFEETGDEKGFNIYILDESNRAEVYHHCEGSKEELVRDVSRFYSSSHDRFTYGS
                     SFINFNLPQFYQIVKTDGRAQVIPFRTQPINTVPPANQDHDAPLLQQYFS"
     gene            3414..4355
                     /gene="hemC"
                     /locus_tag="OPV72_003831"
     CDS             3414..4355
                     /gene="hemC"
                     /locus_tag="OPV72_003831"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HCR9916009.1"
                     /translation="MLDNVLRIATRQSPLALWQAHYVKDALMATHPGLTVELVPMVTR
                     GDVILDTPLAKVGGKGLFVKELEIALLEKRADIAVHSMKDVPVAFPDGLGLVTICERE
                     DPRDAFVSNKYHSLDDLPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLGKLD
                     NGDYDAIILAVAGLKRLGLESRIRTALPPDVSLPAVGQGAVGIECRLDDARTQALLAP
                     LNHSQTALRVTAERAMNTRLEGGCQVPIGSYAEIINGEIWLRALVGAPDGSVMVRGER
                     RGSPEQAEQMGISLAEELLENGARAILTEVYNGETPA"
     gene            4352..5092
                     /gene="hemD"
                     /locus_tag="OPV72_003832"
     CDS             4352..5092
                     /gene="hemD"
                     /locus_tag="OPV72_003832"
                     /EC_number="4.2.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III synthase"
                     /protein_id="HCR9916010.1"
                     /translation="MSILITRPSPAGEALVSRLRALGQVAWSFPLIEFVAGRELPTLA
                     DRLATLTENDLVFALSQHSVAFAHAQLQRDGRNWPASPRYFSIGRTTALALHTVSGFD
                     IRYPLDREISEALLQLPELQNIAGKRALILRGNGGRELLGETLTVRGAEVSFCECYQR
                     CAKHYDGAEEAMRWHTRGVTTLVVTSGEMLQRLWSLTPQWYREHWLLRCRLLVVSERL
                     AHLARELGWQDIKVADNADNDALLRALQ"
     gene            5114..6283
                     /gene="hemX"
                     /locus_tag="OPV72_003833"
     CDS             5114..6283
                     /gene="hemX"
                     /locus_tag="OPV72_003833"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HCR9916011.1"
                     /translation="MTEQEKSSAVVDETRETVETTPQPVNTEKKSKNGAALVLSAVAI
                     AIALAAGIGLYGWGKQQATAQTETSDALATQLTALQKAQESQKAELEGIIKKQAAQLD
                     DANRQQAALAKQLDEVQQKVATISGSDAKTWLLAQADFLVKLAGRKLWSDQDVTTAAA
                     LLKSADASLADMNDPSLITARRAITDDIASLSSVAQIDYDGIILKLNQLSNQIDNLRL
                     ADNDTDGSPMDSDSSELSSSLSEWRVNLQKSWQNFMDSFITIRRRDDTAVPLLAPNQD
                     VYLRENIRSRLLVAAQAVPRHQEETYRQALDNVSTWVRAYYDTDDAATKAFLEEVDKL
                     SQQNITMDLPETLGSQAILEKLMQTRVRNLLAQPTVSTAAPATQTDAPAAAPQGE"
     gene            6286..7482
                     /gene="hemY"
                     /locus_tag="OPV72_003834"
     CDS             6286..7482
                     /gene="hemY"
                     /locus_tag="OPV72_003834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protoheme IX biogenesis protein HemY"
                     /protein_id="HCR9916012.1"
                     /translation="MLKVLLLFVLLLAGIVVGPMIAGHQGYVLIQTDNYNIETSVTGL
                     AIILIVAMVVLFAIEWLLRRLFRTGAHTRGWFASRKRRRARKQTEQALLKLAEGDYQQ
                     VEKLMSKNADHAEQPVVNYLLAAEAAQQRGDEARANQHLERAAELAGNDTIPVEITRV
                     RLQLARNENHAARHGVDKLLEVTPRHPEVLRLAEQAYIRTSAWSSLLDIIPSMAKAHV
                     GDEAHRAMLEQQAWIGLMDQARAEQGSEGLRTWWKNQSRKTRHQVALQVAMAEHLIEC
                     DDHDMAQQIIIDGLKRQYDDRLVLPIPRLRTNNPEQLEKVLRQQIKTVGDRPLLWSTL
                     GQSLMKHGEWQEATLAFRAALKQRPDAYDYAWLADALDRLHQPEEAAAMRRDGLMLTL
                     QNNPPQ"
BASE COUNT         1887 a         2154 c         2145 g         1662 t
ORIGIN      
        1 ttcttcgaat gtaggctgga taaggcgcgt tagcgccgcc atccggcaca gtatcgctct
       61 aaagccataa tcatattgat aagaataatg accacacatg tgagcattaa cgcggtaaaa
      121 aacaaaaagg cgataccgta caatccccat cccaggtcat agagagaatg gtaattgtcg
      181 caggagatga tcacatccag gccggggcat acttttcccc atcgccccca gtaagacgca
      241 tcccagagtt gcaaactggc catgctggcg catagcgaga gcaggcaccc agcggatata
      301 aaacagaata acttatttat aagaatgaag ccgaggctga ccatcgccat gactatccct
      361 aacaaaatga acgcatctgc cacctcaaac ctcctcctgt aaaccaaatg cggaggtcac
      421 ggtaacgaag ttgggtgaag ttaatgtgaa gcggtgaacg ccggccgggc agcgttgccc
      481 ggcgcagcac ttacgaaaaa tactgctgca atagcggcgc gtcatgatcc tggtttgctg
      541 gcggcacggt gttgataggc tgcgtacgga atgggatcac ctgcgcgcgg ccatcggttt
      601 tcactatctg gtagaactgc ggcaggttga agttgataaa gctggagcca tacgtgaagc
      661 gatcgtgcga tgacgaatag aagcgactga cgtcgcgcac cagttcttcc ttgctaccct
      721 cgcagtggtg atacacttcc gcccggttac tttcatccag aatataaata ttaaagcctt
      781 tctcatcgcc cgtttcttca aagaagaact ggataatccc ttcgctggcg aagccatcca
      841 ccactgacgg caatttcacc tggttggttt ccacctgtac cgacagcccg tgcagcttgt
      901 tatgcgaaat cgcgccgtag aattcgatag cgttctccag cttctgcacc gagacattca
      961 agcgttcgaa gaatagtccc cacgtctgcc cggaaacccg cagcgccttg aagcgaccgg
     1021 tctcctgacg ggtgctggaa agacgtagct cgatacattc ggagaccagt tgctgcacgc
     1081 gggtgcgaat cagaccgcga agatgctgac tgtaacagaa cacctccacg ctatccggcg
     1141 gcgcggcatc ctggtgcatt ttccccagaa tcgttttcag cgcttcgatc atcgcctgct
     1201 cgccgttaaa gtgcagagta cgcacttcgt tccacgagtt gcgatataac aagtcgatac
     1261 tgcctatcag acagttttgc tcttcgccaa agctgaaaac gtccagctta cggaagtcaa
     1321 aatgaaccac tttattgcga aacgccgccg tcgggtcata ttcgaggtta acgataatcg
     1381 ccagatggcg aatttcacag gggctgtaga gcgctttcgg cgttggagca ggcaagcgca
     1441 gcgggaaatg gtgcgaaaca tcggcgacca tctcctgcaa cttaggcagg tcgacaatac
     1501 cgttgccctt aataaacaga tgcgttcgcg acgtcagcag gccgttgaac cacgcccacg
     1561 cgaccagctt attaagataa cggttatatt ccagcggctg atggctgatg atggaatcca
     1621 tgttcggcgc gcggttgtag agataccagc ctgaacggtt ggcacgtccc ggcggcacat
     1681 ggataaaggt taaattcggc tcggacagat ccggcgatat ctgcgggttc accagcgtga
     1741 ctttacccgg caacgcttca aacgccgcgt acagcttacg cgtcagtacg ccgatatcct
     1801 gcgggctggc actcacgctg aggttgttgc gccgcgcaaa gcgaatcaga ttacgatagc
     1861 tttgcatcat tgcgtcgagc aattcgttgt gggcttcgcg cacctgatcg attttccagt
     1921 ttgcgcgatt atcgagcatg gtcagacgcg cgtcgtccca tccccactcg ctgaccaact
     1981 ggcttaatac ttcccgacgc cagcctacgc aggcgcgctc gcgacttaat ttctcgcaca
     2041 ctttcaggta aaagcagcgg cggactaaat ccagccgcgt cggatcttca atcgccgtca
     2101 ggtattcagt gacccgttcc agcatcatgc agtagggatc gagtccaaac gatacgattt
     2161 caccgtcatg cagacgttgt ttaatatctt tcgccagcag acgtgggttg gggtattccc
     2221 atgaataggc ttccagcaac agcgttttca gcaccgcttt gtacggcgag tcaatgctct
     2281 tgtatagctg ccacaggctg gcgccaaagt actcttcggc ggagagcgag cttaagcccc
     2341 ccaaatccag ccattcgttt ggcgttaata cgccctgcgc gtagagcgtc atgacatagt
     2401 cgtcgtaatg ctcttcttcg tcgcacggca ccatactcca caggatacgc ttcccggcca
     2461 ggcgcacagc ggtacgataa aactcatcaa gcaacaggat atgctgcgta gaaccacagt
     2521 cttccccgcc cagactgccg ctttcgttat ggcggaaacg gttctcgtca atcaggaaga
     2581 agctcacctc aacgccaagc gaggcggccc agctttccag caggctacac ttacgttgca
     2641 gcaactgacg ctcttcgccg tcgagccagg actgatggca cacccagata tccaggtcgg
     2701 acgagcagct ctgcccgacc gaggaggtgc tgcccatggt gtaaacgccg gtaatcggca
     2761 actcgccctt cggcggatcc tgcggcgtca taccgcggta cagctcaagt tcgttcagat
     2821 agtggcgttg ggtttcatca ggcgtgtaga agcaaatacc gctgggaacg ttaccatcaa
     2881 ggtaacccgg catcagtgga tggtgatagt gcaataatgt cggcagaaga ctgtaaacct
     2941 gctgaaaagc gggtcccatg gcagcaagcg cgcgatccac acgcagttga tttatggcat
     3001 ccagtctctg tttcagagtc tcaatataga ggtacaagac gtatcgcctg atgttgctac
     3061 ccgtcatggt gcaggtcaat acttcaccgt cgccattcgg gataaaccgt atgtcaaaaa
     3121 taaccgttac cctttctcgc ctgcatattt ttatctaata ccgacgaaaa aatggtctaa
     3181 aacgtgatca atttaacacc ttgctcattg accgtaaaga aagatgcgct acatacaagt
     3241 gtagcaccgt tcgctgcgtg taaattctta aatacgggct ggcggtttct cgtcattatt
     3301 cactgtcatt gacgacactg cgccttatcc tctcactcac ggtgaccgga aaactaacat
     3361 actctctata aggatgttag gatggtcaat gattgataat gacggtaaca agcatgttag
     3421 acaatgtttt aagaattgcc acacgccaaa gtccccttgc gctttggcag gcacattatg
     3481 tcaaagacgc attgatggca acccatccgg gactgacggt agaactggtg ccgatggtca
     3541 cacgcggcga cgtgattctc gatactcccc tggcgaaagt gggcggtaag ggactgtttg
     3601 ttaaagagct tgaaatcgcg ctgctggaaa aacgcgctga tatcgccgtg cactctatga
     3661 aagacgttcc ggtggccttc ccggacggtc tcggtctggt gaccatttgc gagcgcgaag
     3721 atccgcgcga cgcgtttgtc tcgaataaat atcacagtct ggacgatctg cccgcgggta
     3781 gtatcgtcgg gacgtccagt ttgcgtcgtc agtgtcaact ggcggaacgc cgtccggatc
     3841 tcattatccg ttcgttgcgc ggcaacgtcg gcacacgtct cggcaagctg gataacggcg
     3901 actatgacgc cattatcctg gccgtggccg gtctgaaacg cttaggtctg gagtcgcgca
     3961 ttcgcacagc cttgccgcct gacgtttcgc ttcctgccgt aggccagggc gctgtcggga
     4021 ttgagtgtcg tcttgacgac gcgcgaacac aggcgctgct cgcaccgttg aatcactcgc
     4081 aaaccgcgct gcgcgtaacg gcggaacgtg ctatgaacac ccgcctggaa ggcggttgtc
     4141 aggtgccgat tggcagctat gcagaaatca tcaacggtga aatttggcta cgcgcgctgg
     4201 ttggcgcgcc ggacggttcg gtgatggtgc gcggcgaacg tcgtggttct cccgagcagg
     4261 cggagcaaat gggcatctcg cttgcagagg aactgctgga aaacggcgcg cgcgcgattc
     4321 tgacggaagt ttataacggc gagacgcccg catgagtatt ctgatcaccc gcccctctcc
     4381 cgcaggggaa gcgttagtga gccgtctgcg cgcactgggg caggtggcct ggagttttcc
     4441 actgattgaa tttgtcgccg gtcgggagct acccaccctg gccgaccgcc tggcaacgct
     4501 gacggaaaac gatctggttt ttgccctttc acagcactcc gtcgcctttg ctcacgccca
     4561 gctccagcgg gatggacgaa actggcctgc gtcgccgcgc tatttctcga ttggccgcac
     4621 tacggcgctc gcccttcata ccgttagcgg gttcgatatt cgttatccat tggatcggga
     4681 aatcagcgaa gccttgctac aattacctga attacaaaat attgcgggca aacgcgcgct
     4741 gattttgcgt ggcaatggcg gccgcgaact gctgggcgaa accctgacag ttcgcggagc
     4801 cgaagtcagt ttttgtgaat gttatcaacg atgtgcgaaa cattacgatg gcgcggaaga
     4861 agcgatgcgc tggcatactc gcggcgtaac aacgcttgtt gttaccagcg gcgagatgtt
     4921 gcaacgactc tggtcgctga ctccccagtg gtatcgtgag cactggttac tacgctgtcg
     4981 gctattggtc gtcagtgagc gtctggcgca cctcgcccgg gaactgggct ggcaagatat
     5041 taaggtcgct gataacgccg acaacgatgc gctgttgcgc gcattacaat aactctcata
     5101 atgggatgcc ataatgacgg aacaagaaaa atcctccgcc gtggttgatg agaccaggga
     5161 gaccgtggaa accacgccac agccagttaa taccgagaaa aaaagtaaga acggcgccgc
     5221 gctggtatta agcgcggtgg cgatcgcgat tgccctggcg gcaggtattg ggctttatgg
     5281 ctggggaaaa cagcaggcaa ccgcgcaaac ggaaaccagc gatgcgctgg cgacgcaact
     5341 gaccgccttg caaaaggcgc aggagagcca aaaagcggag ctggaaggga ttatcaaaaa
     5401 acaagcggcg cagttagatg acgcgaatcg ccaacaggcg gcgctggcga aacagcttga
     5461 tgaagtacaa caaaaagtcg ccaccatttc cggcagcgat gctaaaacct ggctgctggc
     5521 acaggctgat ttcctggtga aactcgccgg acgcaagctg tggagtgatc aggacgtcac
     5581 taccgccgct gcgctgctca aaagcgctga cgccagtctg gcggatatga atgaccccag
     5641 cctgattacc gcacgacgcg cgattactga cgatatagcc agcctgtcat ccgttgcgca
     5701 gatcgactac gacggcatta ttctcaagct caatcagctc tctaaccaaa ttgataacct
     5761 gcgtctggcg gataacgata ccgatggttc gccgatggat tctgacagca gcgagctgtc
     5821 cagctcgcta agcgaatggc gcgttaacct gcaaaaaagc tggcagaact ttatggacag
     5881 ctttattacc attcgccgcc gcgatgatac cgccgtaccg ctgttggcgc ccaaccagga
     5941 cgtctattta cgcgaaaata ttcgctcccg cctgttagtc gccgcgcagg ccgtgccacg
     6001 ccatcaggaa gaaacatacc gtcaggcgct ggataacgtt tcgacctggg ttcgcgctta
     6061 ttacgatact gacgacgccg cgacaaaagc cttcctggag gaggtcgata aattaagcca
     6121 gcaaaatatc acgatggatc tgccggaaac tctgggaagc caggcgattc ttgaaaaact
     6181 gatgcaaacc cgcgtgcgta atctgctggc gcaaccgaca gtctctacgg cagcgcctgc
     6241 cacgcagaca gacgctccgg cagccgcgcc gcaaggagaa taatgatgct aaaagtatta
     6301 ttgctctttg tgttgttgct cgcgggtatc gtggtcggcc cgatgatagc cggtcaccag
     6361 ggctatgtgt taatccagac cgataactac aacattgaaa ccagcgtcac cggcctggcg
     6421 atcattctca tcgtcgctat ggtggtgcta ttcgccattg agtggttact acgccgtctg
     6481 tttcgtaccg gcgcgcacac ccgcggttgg tttgccagcc gtaaacgccg tcgcgcccgc
     6541 aagcagaccg aacaggcgct gctgaagctg gcggagggcg actatcagca ggttgaaaag
     6601 ctgatgtcaa aaaatgccga ccatgctgaa caaccggtgg taaattattt gctggcggca
     6661 gaagcggcgc agcagcgcgg cgatgaagca cgcgctaatc agcaccttga acgtgcggca
     6721 gagctggcgg ggaacgacac catcccggtc gagatcacgc gtgtgcgctt acagctggcg
     6781 cgcaatgaaa atcacgcagc gcgtcacggc gtggacaaac tgctggaggt cacgccgcgt
     6841 cacccggaag ttctgcgtct ggcggagcag gcctatattc gcaccagcgc atggagttct
     6901 ttactggata tcatcccatc catggcgaaa gcgcacgtcg gcgatgaagc gcatcgcgcc
     6961 atgctcgaac aacaggcgtg gataggactc atggatcagg cgcgtgccga gcagggcagc
     7021 gaaggattac gcacctggtg gaaaaaccaa agccgtaaaa cccgccatca ggtggcgctg
     7081 caggtcgcga tggccgagca tctaatcgag tgtgacgatc atgatatggc gcagcagatt
     7141 atcatcgacg gtctgaaacg ccagtatgac gatcggctgg tgctgcccat tcctcgcctc
     7201 agaaccaata atccggaaca actggagaaa gtgctgcgcc agcaaatcaa gacggtaggc
     7261 gatcgcccgc tgttatggag cacgctcggc cagtcgctaa tgaaacacgg tgaatggcag
     7321 gaggcgaccc tggctttccg cgccgcgctg aaacaacgcc cggacgcgta tgattatgcc
     7381 tggcttgccg atgcgcttga tcgactgcat caaccggaag aggccgccgc catgcggcgc
     7441 gacggcttga tgctgacatt acagaacaat cccccgcagt aattccctct tgcccggtgg
     7501 cgcttcgctt accgggctta ccgcctacac aaaatcattc gggatgcata aaaaaacgcc
     7561 tgcccggtta aggggcaggc gtcaaaacag gtctgtatga caacataaag gggtgcttca
     7621 ctcaacgttg tgtccagggt gtttgatgag gcgtaagcga catctgtcag tggacgataa
     7681 gcaccgtaaa cggctctgca tcattcctga gtttatgagg ccagaaggcg aacataagag
     7741 atggaatgag catctacccg tacattattg cacataacgt gccatctttg caccgctaaa
     7801 aaacaggcgc aggcattaaa aaaacgtaga gaattcacgc gattgtta
//
LOCUS       DAJVBX010000202         7746 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.202, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000202 DAJVBX010000000
VERSION     DAJVBX010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 7746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7746
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.202"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            312..797
                     /locus_tag="OPV72_003835"
     CDS             312..797
                     /locus_tag="OPV72_003835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system tube protein Hcp"
                     /protein_id="HCR9916013.1"
                     /translation="MDAIFLKLDNIKGESQVEGFEDQIEIMSYSHNVAMQVNNDVSLT
                     ERTSGRAHVGEMSLTKFVDLATPVLNEYCCSGRLIRTAVLTLCRNDDGKMRSLIVYTL
                     TNVLISQLSVSGGAGGKPVETMSLNFTKIKWQITAEKSDGAQQESRASVWDLAMDQIG
                     K"
     gene            797..1177
                     /gene="iraD"
                     /locus_tag="OPV72_003836"
     CDS             797..1177
                     /gene="iraD"
                     /locus_tag="OPV72_003836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-adapter protein IraD"
                     /protein_id="HCR9916014.1"
                     /translation="MMTPTIPVALFDRLLVEGISPHELVRRKLICLFNSCAVPGGETL
                     PPLLTRGMPEWHEVNVGDKRVLNWFCRELRAAILRYEPSINMLKVSVKDAYHQTLALS
                     LEAMLQDESEPLRLEIAYSNGRWR"
     gene            complement(1313..2797)
                     /locus_tag="OPV72_003837"
     CDS             complement(1313..2797)
                     /locus_tag="OPV72_003837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent phenylacetaldehyde dehydrogenase"
                     /protein_id="HCR9916015.1"
                     /translation="MSDVTLLAEVTTFLRQRHGQFIAGERQAGNGTNFSVTNPATGKI
                     IADVVSTTPAQAKEAMQSARRAFDVWRKMPTLQRGALLLKLADTLAAHREELAQLESV
                     CSGKTIMLSRGLELDQSVAFLRYFAGWAGKITGETLNVSLPSMGEERYTAFTQRQPIG
                     VVVGIVPWNFSIMIAIWKLAAALVCGCTIVIKPSEYTPLTLLRVAELAKEAGFPDGVI
                     NVVNGAGGEIAQQLIAHPDCAKVSFTGSVATGEKVRRSATSSGKRVTLELGGKNAALF
                     LNDLTAQAMVNGILEAGYLNQGQICAAAERFYLPQEKLDTVMTLLRQRLSEIVPGSPL
                     DEKTVMGPLANQVQLEKVLRLIQRAREEGDTIVYGGETLPGEGYFLQPTAVKVRSKNS
                     TLMHEETFGPVCSFIGYQNEKEALSHINDSPFGLAASVWSENISKALRYAEDIDAGMV
                     WVNMHTFLDPAVPFGGMKGSGIGREFGSAFIDDYTELKSVMVRY"
     gene            2959..4260
                     /locus_tag="OPV72_003838"
     CDS             2959..4260
                     /locus_tag="OPV72_003838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HCR9916016.1"
                     /translation="MNTKIDALNYYGATKKYPLHFPALQDDIDADVVIIGGGFSGINT
                     ALELAEQGITNVVVLEARHLGYGGTGRNGGQVMAGIGHDIEAVKKYVGAAGMETLFKI
                     SNLGAGIIRERIRKYHIDADFVPGYGYLAYNQRQLKTLQQWEKEFKAATPEDDIELYT
                     GKDVQQVIGSDVYCGVLKHMGGGHVHSLNLLLGSAQAANSLGVKIFEYSPVVEVSYGK
                     TVRVRTAMGSVKAAKLLWACDSFLNNLEPEIYKKTLVTYSYQVSTEPLSSELVERISP
                     LRGAFSDIRPVINYYRLTKENRLLFGSATRFLEYTPHDFAAWNRTLLTEVFPYLKDVK
                     IDFAWGGPMACSANLFPQIGTLREHNNVFYVQGYSGFGVTPSHIVCKILAEGINGGSE
                     RYRLMSSIPHATIYGRDSLRLLLVSAGKLIHQTAGFWKGRN"
     gene            4275..4648
                     /locus_tag="OPV72_003839"
                     /pseudo
     CDS             4275..4648
                     /locus_tag="OPV72_003839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462042.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
     gene            4857..6356
                     /locus_tag="OPV72_003840"
     CDS             4857..6356
                     /locus_tag="OPV72_003840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HCR9916017.1"
                     /translation="MFKNRLASHLERGVIGFPTTLASSVGLIMASPVILTVTSGFGSG
                     GDTFALAVLLAFIMMQAQITTFAEAATLIPTTGSVYDYISCGMGRFFAITGALCAYLI
                     VHIFAGTAETILAGVMALVNFESVSEHVAMQHNTWMVGVGMVVVFGILNAIGVEVFGK
                     VEVFLTFGMWTTLTIFGLCGILLSPVTHHSGWFGAPLDVSNLSGLFGYIGMAMFMFVG
                     CELVTPMAPEIKKAHRTIPRAMALGLLAVAGCMFLYGAAINRQVNNVVVDAANHIFLL
                     DTPMAIPAFANRVMGHVGQYWLGVGLLLAGCATINTLMAAVPRIIYGMALDGALPRFL
                     TWLHPRFKTPVIAIAFGVAIPCLHAWYLNGDIDHIVPLILAAVCAWGVAYLLVTLSVV
                     ILRIRRPDLPRAYRAPWFPLPQIISSVGIIIAIINIAPPGMNSRDVLIPFGIMLGLTA
                     AYALFWTLCVQRVNPFLPLPVEEVVERAMGNYEKRNNEEMTPDVLRPLV"
     gene            6334..6891
                     /locus_tag="OPV72_003841"
     CDS             6334..6891
                     /locus_tag="OPV72_003841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3156 family protein"
                     /protein_id="HCR9916018.1"
                     /translation="MSSVPWFKNALMNMVLRDLSGWRCEKLTEHSAVLHLNAFTQVIC
                     HVQQKRLFMASIHSCEFRVKGTINYPLQGKIRAHQPGWLKRYPVIFTGSKSTAGLISY
                     LNRFPNLQQALSELDYRRFTLVLHHKEWYCSIELWAASEVVCKMPPLRRYLRLERHQR
                     VLLLSVINMINQAMNQWLQQDADAR"
     gene            complement(6996..7679)
                     /locus_tag="OPV72_003842"
     CDS             complement(6996..7679)
                     /locus_tag="OPV72_003842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LuxR family transcriptional regulator"
                     /protein_id="HCR9916019.1"
                     /translation="MSALSTTGHNDGITLHCLQSIAQLIPLSSAVFYRVNAYLKPEAY
                     VLHNISNSTHQQYLEHFQPLDPLLPSRFGQQVITVATMTPGICARHRHYYHEFMLPNH
                     VCDMIEIFIRRGHRIIAGISLMRDIPFSSEERLRAQAVQPLLGLAIHDSLQEDNDLAS
                     ILTAKEREIVGMVCEGASNKLIARQLNISLSTVKTHLRNIFAKTEVINRTELVSRTRM
                     SSVQHSLNM"
BASE COUNT         1882 a         1823 c         1999 g         2042 t
ORIGIN      
        1 tcaatttttg aataacgacg ctgtgatacc ggcaccaggg atactttgcg ataaaaggga
       61 ttgaatatgg cagagagcgt tcagtataac ctcaattgta tttggccaca gcgggccaaa
      121 accctctatt gcattgcaac cagcggaata acgttcatca gacgtgggta aacgttggca
      181 aaatccctgc aaacctggcg cttttcacgc tgtgtttttt ggtcgttgcg cttttaataa
      241 gagtcacaag cgttggccgc cggtattcgt ctggctgctg aactgccacc tgatcaacaa
      301 ggagataaat catggatgcg atttttttaa agctcgacaa tatcaaaggc gaaagccagg
      361 ttgaaggctt tgaagatcag atagagatca tgtcttatag ccacaatgtg gcaatgcagg
      421 taaataacga tgttagcctc actgagcgga cttccgggcg tgcgcatgtt ggtgaaatgt
      481 cgctcaccaa atttgtcgac ctcgccacgc ctgtgctcaa tgagtactgc tgtagcggga
      541 ggctaattag aaccgcggtg ctgacgttgt gccgcaatga cgacggcaaa atgcggtcgc
      601 ttatcgttta taccctgaca aacgtgctga tatcacaact cagtgttagc ggcggcgccg
      661 gcggtaagcc ggtggaaacg atgtcgctga acttcacgaa aatcaaatgg caaatcactg
      721 ccgagaaatc agacggcgct caacaggagt ccagagcgtc agtatgggat ctggcgatgg
      781 accagatagg gaaatgatga tgacgccaac cattccggtc gcgctattcg acaggctctt
      841 ggttgagggg ataagcccac atgaattggt acgccgcaaa ttaatatgtt tattcaactc
      901 ttgcgccgtg ccaggtggcg agacattacc gccgctgctc actcggggta tgccggaatg
      961 gcacgaggtg aatgtgggtg acaaacgggt tctcaactgg ttttgccgtg agcttcgcgc
     1021 tgctatttta cgttatgaac cgagcatcaa catgctgaaa gtcagtgtaa aagatgccta
     1081 tcatcagacg ctggcgttgt ctttggaagc gatgttacag gatgagtctg aaccgttaag
     1141 actggagata gcctactcta acggtagatg gcgctagtaa tgcaggaagg aacgccgggc
     1201 cgggcgttta acattatccc aaaagcaaaa aaacgcagcg agcgaacctg ataatcaggc
     1261 agacagtcct cctttcggta tggttgatct gcctgcatca ttttcaggat ggttaataac
     1321 ggaccatgac cgatttaagt tcggtatagt catcaataaa cgcgctgcca aattcacgac
     1381 caatgcccga tcctttcatc cctccaaagg gtaccgcggg atcgaggaag gtatgcatat
     1441 taacccacac catgccagca tcaatatctt cagcgtagcg taatgcctta gatatatttt
     1501 ccgaccacac acttgcagca aggccgaatg gcgaatcgtt gatatgcgaa agcgcctctt
     1561 tttcattctg ataaccgata aagctacaga cagggccaaa ggtctcctcg tgcatcagcg
     1621 tactgttttt actacgcact tttaccgctg tcggctgtaa aaagtaccct tcgccgggta
     1681 aagtttcacc gccgtaaaca atggtatccc cttcttcccg tgcacgttga atcagacgca
     1741 gcactttttc aagctgaacc tgattcgcca gcgggcccat caccgttttt tcatctaaag
     1801 gcgagccggg cacgatctcc gataaccgtt gtctgaggag cgtcatgacc gtatccagtt
     1861 tttcctgggg cagataaaaa cgctctgcgg cagcacaaat ctgtccttga ttcagataac
     1921 cggcttcaag aataccgttg accatggctt gtgccgtgag atcattgaga aacagcgccg
     1981 catttttccc tcccagttcg agggtaacgc gttttcctga cgacgttgcc gaacgccgga
     2041 ctttctcacc tgtcgcgact gacccggtga aactcacttt ggcgcaatct ggatgcgcga
     2101 tcagctgttg cgctatctca ccgccagcac cgtttaccac gttaattacg ccatcaggga
     2161 aaccagcctc tttagccagt tcagcgactc gcagcagtgt cagcggggta tattcacttg
     2221 gtttaatgac gatggtgcag ccacatacca gcgctgcggc cagcttccag atagcaatca
     2281 taattgagaa attccacggc acaataccga cgaccacgcc aatgggttgg cgttgggtaa
     2341 acgctgtgta tctctcttct cccattgatg gcagggagac attcagcgtt tcaccggtta
     2401 tttttcctgc ccaaccggca aagtaacgca ggaaggccac tgactgatcg agttcaagac
     2461 cgcgcgacag cataatcgtt ttacctgaac agacgctttc cagttgagct aactcttcac
     2521 gatgagcggc aagagtatca gccagtttca gcagtaatgc gccgcgttgt aacgttggca
     2581 ttttacgcca gacatcaaac gcccgtctgg cgctctgcat ggcctctttt gcctgcgcag
     2641 gggttgtcga cacaacgtcg gcgatgattt tgccggtggc tgggttagtg accgagaagt
     2701 tcgtgccgtt tccggcctga cgttcacctg caataaattg tccgtgtcgt tggcgtaaaa
     2761 aagtcgttac ttcggcaagt aatgtcacgt cgctcatcag aagtgcctgt aggtcaggaa
     2821 tgtacgtttt tccatctcaa catacttgcc tggaactgaa tatcgttcca aagaacgtca
     2881 ttcttccgga cgatattttg taaaacgtta ccgtgctgtg atagcggtct tggtcaagcg
     2941 tgatgacaag gtaacgcgat gaatacaaaa atcgatgcgt tgaattacta cggcgcgacg
     3001 aaaaaatacc cgttgcattt tcctgctctg caagacgata ttgatgccga tgtggtgatc
     3061 attggcggtg gcttttcagg catcaatacc gcgctggaac tggcggagca ggggatcact
     3121 aatgttgtcg ttctggaagc ccgccatctt gggtatggcg gcaccgggcg aaacggcggt
     3181 caggtgatgg ccggtatagg tcacgacatc gaagccgtta aaaaatatgt aggcgcagcg
     3241 ggaatggaga cgctgtttaa aatctcgaac ctcggcgcgg gtattattcg ggagcgaatt
     3301 cgtaaatacc atattgatgc tgattttgtc cccggatatg gttatctggc ctacaaccag
     3361 cggcagttaa aaacgctgca acaatgggaa aaagaattca aagccgctac gccggaagac
     3421 gatattgaac tctataccgg taaagacgtg cagcaggtta tcggttccga cgtctactgc
     3481 ggtgttctca agcatatggg gggagggcat gtccactcgc tgaatttatt gctgggctcc
     3541 gctcaggctg cgaattcgct gggggtgaag atattcgaat attcacctgt ggttgaggtc
     3601 agttacggta aaactgtgcg ggtacgtact gcgatgggca gcgtaaaagc agccaaattg
     3661 ctgtgggcct gtgatagttt tctcaataat ctggaaccag aaatttataa gaaaacgctg
     3721 gttacttatt cttatcaggt ctctacagaa cctctctcca gcgagcttgt tgagcggatc
     3781 agtcccttgc gcggggcttt tagcgatatc cgcccggtga taaattacta ccgtctcaca
     3841 aaagaaaacc gtctgctgtt tggcagcgcc acaaggtttc ttgaatatac cccgcacgat
     3901 tttgctgcct ggaaccgcac tctgttgacg gaggtctttc cttatttgaa agacgttaaa
     3961 atcgattttg cctggggcgg accgatggcc tgtagcgcga atctgtttcc gcagattggc
     4021 acgcttcgtg agcacaataa tgttttttat gttcagggtt attccggatt tggcgtcacg
     4081 ccttcccata ttgtatgcaa aatcctggcc gaaggaataa atggcggttc cgagcggtat
     4141 cgtctgatga gtagcattcc ccacgcgaca atttatggtc gcgacagtct acgtctattg
     4201 ctggtcagtg cgggaaaact gatacatcaa acagccggtt tctggaaagg ccggaattaa
     4261 ccaggagaac attaatgcac gcttttaaac tcaatcaacc tgttcctgaa ttacagccag
     4321 tcgggagtgt cagcctgtta ggggcgttgc caacagaagg cgtccccagg tcgccgttgc
     4381 gatgatttac ggtaaacctg aggacgtatt tacctgtgga ctgttttcat cgacccgcgg
     4441 cggtttcact atgatttatc cctttaccga gcacgcaacc gtgctggaag gggaagtgga
     4501 actcactgtt gtgggtcagg aaccgatacg tttttcaccg ggcgatagtt ggtttgttga
     4561 acagggaacc gaagtggcat ggaaagtttt aacgccccgt tttgtaaaac attatctggc
     4621 aaacgttgaa agccataaac agggttgaac cctttaattg ttcgtcagta gcgttggcat
     4681 cactggggag aataacgcgc tccccacttg ctattagcgc atgcggggac ggcgtcacaa
     4741 cgttatttac cgttatccct cttcaggacg atacctgtta gatgcgctgc ctgccataaa
     4801 taagcgttat tccggagcgg taatttattg ttgtaataat agtgaagagg ttgaccatgt
     4861 ttaaaaacag acttgccagc catcttgaac gtggcgttat tggtttcccc acgacgcttg
     4921 ccagctccgt cgggctgatt atggcaagcc cggtgatcct gaccgtgacc agtggttttg
     4981 gctcaggggg agataccttt gcccttgcgg tattactggc atttattatg atgcaagcgc
     5041 agattaccac ctttgccgaa gcggcaacgc tcattcccac gactggctcc gtctacgact
     5101 atatctcctg cgggatgggg cgttttttcg ctatcaccgg tgcgctttgc gcttacctga
     5161 tcgtacacat ttttgccggc acggcagaaa cgattctcgc tggcgtcatg gcgctggtga
     5221 actttgagtc cgttagcgaa cacgtggcca tgcagcacaa tacctggatg gttggcgtcg
     5281 gcatggtagt ggttttcggg atactgaatg ccattggtgt tgaagtattt ggcaaggtgg
     5341 aagtgtttct tacattcggt atgtggacta ccctgaccat cttcggttta tgcgggatcc
     5401 tgttatcccc ggtcactcat cattccgggt ggtttggcgc accgcttgat gtcagtaatc
     5461 tttctggtct gtttggttat ataggcatgg cgatgtttat gttcgtcggt tgtgaactgg
     5521 tcacgccaat ggcgccggaa attaaaaaag cgcatcgtac gattcccaga gcgatggcgc
     5581 ttggcctttt agcggtggca ggttgtatgt tcctctatgg cgctgcgatt aaccggcagg
     5641 taaataatgt ggtggtcgat gcggcaaacc atatcttttt actggatacg ccgatggcta
     5701 ttcccgcctt tgccaatcgt gtcatgggac atgtcgggca atactggctg ggcgtggggt
     5761 tgttgttagc gggatgtgcg acgattaata cgctaatggc ggcagtaccg cgtattatat
     5821 acggcatggc gctggacggc gctttgccgc ggtttctgac ctggttgcac ccccgcttta
     5881 aaacaccggt catcgccatc gcattcggtg ttgcgattcc ctgtttacat gcctggtatc
     5941 tgaacggtga tatcgaccac attgttccgc tgatcctcgc tgcggtctgc gcctggggag
     6001 tagcttatct gctggtaacg ttatcggtcg ttatcttacg tattcggcgc cccgatttac
     6061 cacgcgctta ccgggccccc tggtttccct tacctcagat tatttcgagc gtgggtatta
     6121 ttatcgccat tattaatatc gcgcctccag gaatgaacag tcgggatgta cttataccat
     6181 tcggtattat gcttggattg actgccgcct atgccttatt ctggacatta tgtgtgcaac
     6241 gggttaatcc tttcctcccg cttccggtag aagaggtcgt ggaacgggcg atgggcaatt
     6301 atgaaaagcg aaacaatgaa gagatgacgc cagatgtcct ccgtcccctg gtttaagaac
     6361 gcattaatga atatggtgtt acgtgatttg agcggctggc gttgtgaaaa attgaccgaa
     6421 catagcgccg tgctgcatct gaatgcattt acccaggtta tctgccatgt tcagcaaaaa
     6481 cggttattca tggccagtat tcacagttgt gaattcaggg tgaaaggcac aatcaattat
     6541 cctttgcagg gcaaaattcg cgctcatcag cccggatggc tgaaacgtta tcccgtcatt
     6601 tttactggca gtaaaagtac cgccgggctg attagctatc ttaatcgttt ccccaattta
     6661 caacaggctc tgagtgaact ggattatcgt cggtttactc tggttttaca tcataaggaa
     6721 tggtattgca gcattgagct atgggctgct agcgaagtgg tttgtaaaat gccgccgctg
     6781 cgccgttatc tgcggcttga gcggcaccag cgtgttcttc tgcttagtgt gataaatatg
     6841 atcaatcagg ccatgaatca atggctgcaa caggatgccg acgccagata atatgacatt
     6901 ttattgcggc atcagctcag agggtggtat taattcaggc atatatgaca tatggggaaa
     6961 agacccgcaa ttgacgcggg ttaaaaagaa cgctttcaca tattcagtga atgttgtacc
     7021 gaggacattc tggttcggga aaccagttcc gtgcgattta tcacttctgt tttagcaaaa
     7081 atattacgta aatgcgtttt cactgttgag agagaaatat tcaactgacg ggcaatcaat
     7141 ttgttgctgg ccccttcgca gaccattccc acaatttcac gctctttggc ggtcaatatt
     7201 gacgccagat cgttgtcttc ctgaagagaa tcatgaattg ccagtcccaa taatggttgt
     7261 actgcctggg ctcgcaaacg ctcttcgctg gaaaaaggta tatcgcgcat taatgaaatg
     7321 cccgcgataa tacgatggcc ccgacgaata aagatctcaa tcatgtcgca cacatgatta
     7381 ggtagcataa attcatgata ataatggcga tgacgagcac agatgccggg cgtcatcgtc
     7441 gctactgtaa taacctgttg gccgaatcgg gaaggcaata gcgggtctaa tggttgaaaa
     7501 tgctccagat attgttggtg tgtgctatta gaaatattat gtaaaacata ggcttccggc
     7561 tttaaataag cattaacacg ataaaaaacc gccgacgaca gaggaatgag ttgcgcaatg
     7621 ctctgtaagc aatggagagt gatcccgtca ttatggccag tagttgataa ggctgacatg
     7681 ttatctcctt ccatccggat gagcgcgtcg gggcgcagta aaatagtggt atgttgaaac
     7741 atacaa
//
LOCUS       DAJVBX010000203         7651 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.203, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000203 DAJVBX010000000
VERSION     DAJVBX010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 7651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7651
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.203"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(359..664)
                     /gene="cbpM"
                     /locus_tag="OPV72_003843"
     CDS             complement(359..664)
                     /gene="cbpM"
                     /locus_tag="OPV72_003843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperone modulator CbpM"
                     /protein_id="HCR9916020.1"
                     /translation="MANITVTFTITEFCLHTGVTEEELNEIVGLGVIEPYEDDNADWQ
                     FDDRAASVVQRALRLREELALDWPGIAVALTLLEENSRLREENRLLLQRLSRFISHP"
     gene            complement(664..1584)
                     /gene="cbpA"
                     /locus_tag="OPV72_003844"
     CDS             complement(664..1584)
                     /gene="cbpA"
                     /locus_tag="OPV72_003844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curved DNA-binding protein"
                     /protein_id="HCR9916021.1"
                     /translation="MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEA
                     RFKEVAEAWEVLSDEQRRAEYDQLWQHRNDPQFNRQFQQHEGQPYNAEDFDDIFSSIF
                     GQHGRHSHHRHAARGHDIEIEVAVFLEETLEEHQRTISYSVPVYNAFGLVEREIPKTL
                     NVKIPAGVSNGQRIRLKGQGTPGENGGPNGDLWLVIHIAPHPLFDIVNQDLEVVLPLA
                     PWEAALGAKVSVPTLKERILLTIPPGSQAGQRLRIKGKGLASKKHTGDLYAIIKIVMP
                     PKPDEKTAALWQQLADAQSSFDPRQQWGKA"
     gene            1820..2182
                     /locus_tag="OPV72_003845"
     CDS             1820..2182
                     /locus_tag="OPV72_003845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper resistance protein"
                     /protein_id="HCR9916022.1"
                     /translation="MAKQQRMGWWFLCLACVVVMVCTAQRMAGLHALQMQATASAAVV
                     SAPSSTDDGSPVTPCELSAKSLLAAPPVLFEGAILALYLLLSLLAPVRVMRLPFSPPR
                     AISPPTLRVHLRFCVFRE"
     gene            2231..4117
                     /locus_tag="OPV72_003846"
     CDS             2231..4117
                     /locus_tag="OPV72_003846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HCR9916023.1"
                     /translation="MMILFRRILFCLLWLWLPVSWAAESGWLRSPDNDHASIRLRADT
                     SANSETRLLLDVKLENGWKTYWRAPGEGGVAPSIAWKGDMPEVSWFWPTPSRFDVANI
                     TTQGYHDEVTFPMIVRGTPPATLRGVLTLSTCSNVCLLTDYPFSVTPTVQNADFAHDY
                     ARAMGKVPLRSGLTDSLDVGYRPGELVVTATRAAGWSSPGLYLDTIDDVDFAKPRLRV
                     EGDRLQATVPVTDSWGEKAPDLRDKSLTLVLADGAIAQESTQTIGAAPAQTPDNAALP
                     FWQVVMMALIGGLILNLMPCVLPVLGMKLGSILLVEEKSRSHIRRQFLASVAGIIASF
                     MALAAFMTLLRLSNHALAWGVQFQNAWFIGFMALVMLLFSASLFGLFEFRLPSSMTTK
                     LATYGGNGMSGHFWQGAFATLLATPCSAPFLGTAVAVALTASLPTLWGLFLALGLGMS
                     APWLLVAIRPGLALRLPRPGRWMNVLRRILGLMMLGSAIWLATLLLPHFGFTASKSAQ
                     DTVQWQPLSEQAIQSALAQHKRVFVDVTADWCITCKVNKYNVLQKEDVQAALQQPDVV
                     ALRGDWTLPSDAITDFLKTRGQVAVPFNQVYGPGLPEGEALPTLLTRDAVLQTLKKAK
                     GITQ"
     gene            4114..4737
                     /locus_tag="OPV72_003847"
     CDS             4114..4737
                     /locus_tag="OPV72_003847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HCR9916024.1"
                     /translation="MKYMIVLLLALFSTLSIAQETAPFTPDQEKQIKNLIHAALFNDP
                     ASPRIGAKHPKLTLVNFTDYNCPYCKQLDPMLEKIVQKYPDVAVIIKPLPFKGESSIL
                     AARIALTTWRDHPQQFLALHEKLMQKRGYHTDDSIKQAQQKAGATPVTLDEKSMETIR
                     TNLQLARLVDVQGTPATIIGDELIPGAVPWDTLEAVVKEKLAAANGG"
     gene            4727..5233
                     /locus_tag="OPV72_003848"
     CDS             4727..5233
                     /locus_tag="OPV72_003848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein disulfide oxidoreductase"
                     /protein_id="HCR9916025.1"
                     /translation="MAGKLRRWLREAAVFLALLIAIMVVMDVWRAPQAPPAFAATPLH
                     TLTGESTTLATLSEERPVLLYFWASWCGVCRFTTPAVAHLAAEGENVMTVALRSGGDA
                     EVARWLARKGVDFPVVNDANGALSAGWEISVTPTLVVVSQGRVVFTTSGWTSYWGMKL
                     RLWWAKTF"
     gene            5366..6607
                     /gene="agp"
                     /locus_tag="OPV72_003849"
     CDS             5366..6607
                     /gene="agp"
                     /locus_tag="OPV72_003849"
                     /EC_number="3.1.3.10"
                     /EC_number="3.1.3.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glucose-1-phosphatase/inositol
                     phosphatase"
                     /protein_id="HCR9916026.1"
                     /translation="MKKSLLAVAVAGAVLLSSAVQAQTTPEGYQLQQVLMMSRHNLRA
                     PLANNGNVLAQSTPNAWPAWDVPGGQLTTKGGVLEVYMGHYTREWLVAQGLIPSGECP
                     APDTVYAYANSLQRTVATAQFFITSAFPGCDIPVHHQEKMGTMDPTFNPVITDDSAAF
                     RQQAVQAMEKARSQLHLDESYKLLEQITHYQDSPSCKEKHQCSLIDAKDTFSANYQQE
                     PGVQGPLKVGNSLVDAFTLQYYEGFPMDQVAWGGIHTDRQWKVLSKLKNGYQDSLFTS
                     PTVARNVAAPLVKYIDKVLVAERVSAPKVTVLVGHDSNIASLLTALDFKPYQLHDQYE
                     RTPIGGQLVFQRWHDGNANRDLMKIEYVYQSARQLRNAEALTLKSPAQRVTLELKGCP
                     VDANGFCPLDKFDNVMNTAAK"
     gene            complement(6641..6868)
                     /locus_tag="OPV72_003850"
     CDS             complement(6641..6868)
                     /locus_tag="OPV72_003850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002898701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccJ family protein"
                     /protein_id="HCR9916027.1"
                     /translation="MPTQEAKAHRVGEWASLRNTSPEIAEAIFEVAHYDEKLAEKIWE
                     EGSDEVLIKAFEKTDKDSLFWGEQVIERKNV"
     gene            complement(6889..7485)
                     /gene="wrbA"
                     /locus_tag="OPV72_003851"
     CDS             complement(6889..7485)
                     /gene="wrbA"
                     /locus_tag="OPV72_003851"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H:quinone oxidoreductase"
                     /protein_id="HCR9916028.1"
                     /translation="MAKILVLYYSMYGHIETMAHAVAEGAKKVDGAEVIIKRVPETMP
                     PEIFAKAGGKTQNAPVATPQELADYDAIIFGTPTRFGNMSGQMRTFLDQTGGLWASGA
                     LYGKLGGVFSSTGTGGGQEQTITSTWTTLAHHGMVIVPIGYSAQELFDVSQVRGGTPY
                     GATTIAGGDGSRQPSQEELSIARYQGEYVAGLAVKLNG"
BASE COUNT         1648 a         1996 c         2174 g         1833 t
ORIGIN      
        1 cctgtaagcg cagcggtaca ttttacccgg cattgacagg gagaagatac gtatcaacca
       61 gagagtacaa aacagtgaaa gaatatattc ttcaggcaat aaatgatcgc taacgtgtaa
      121 aaataaccga cgaatctaaa aaatgtgagc gtgtggctgg tctttattta aacgatgatc
      181 ttcgcaatgg cgcattaatg gctgacattg gcggttcgtt gatcggcttg tgcgcggtga
      241 aaggctatat ttcttccgtt gcgggaagta tgtcagaggc attctggtat tataccgggt
      301 gtatgtaaat ccggggtggg cagaaagccc accctcggtt tattgccttt atcgtggatt
      361 agggatgcga gataaagcga gaaaggcgtt gcagcagtaa ccggttttct tcgcgcagcc
      421 gtgaattctc ttccagcagc gttaacgcga ccgcgatccc tggccagtcg agcgccagct
      481 cctcgcgtaa gcgtagcgcg cgttgtacca cgctcgctgc gcgatcgtcg aattgccagt
      541 cggcgttatc gtcttcgtaa ggctcaatta cgccaagtcc gacgatttcg tttagctcct
      601 cttccgtcac gccggtgtgc aaacaaaatt cggtgatggt aaaggtgaca gtgatgttag
      661 ccattatgct ttcccccatt gctggcgtgg gtcaaaggac gactgcgcgt ccgccagttg
      721 ttgccacagg gcagctgttt tctcgtcagg tttcggcggc ataacgattt tgatgatggc
      781 atagagatcg ccagtgtgct ttttactggc taatcctttt cctttgatac gcagccgctg
      841 acctgcctgg ctgccggggg gaatggtcag caaaatacgc tctttaagcg ttggcacaga
      901 caccttagcg ccgagcgccg cctcccatgg ggcaagcgga aggacgactt ccagatcctg
      961 attgacgata tcaaagagcg gatgcggggc aatatggata acgagccata aatcgccatt
     1021 aggtccgccg ttttcccccg gcgtgccctg gcctttcagt ctgattcgtt gcccgttgct
     1081 gacgccagcc gggattttca cattcaatgt tttgggaatt tcccgctcca ccaggccgaa
     1141 cgcgttataa acggggacgg aatagctaat cgtacgctgg tgctcttcca gcgtttcttc
     1201 caggaatacc gccacttcaa tttcgatatc atgaccgcgt gcggcgtggc ggtggtgcga
     1261 atgacgaccg tgctgaccaa aaatagacga gaaaatatca tcaaaatctt cggcgttata
     1321 cggctggcct tcgtgttgct ggaactggcg attaaattgt ggatcgttac ggtgttgcca
     1381 taactggtca tactcggcgc gccgttgctc atcactcagc acttcccatg cttcagcaac
     1441 ctctttgaaa cgggcttcgg catcgggttc tttgctgaca tctggatggt acttgcgggc
     1501 cagtcggcga taggcggtct taatcgtctt gagatcgtcc gtcggtttca cgcccataat
     1561 ggcgtaataa tccttaagtt ccatagcatc atctcgctaa atcaatacat acagaaggga
     1621 ccccaaaaag gtttctccac taagtgtagg gtaaacctga aaagtgcgta tgaaaacacc
     1681 agttatatca ttagtaagaa taaattacgt tgttcgacta tcagaaggtt gcgcagcgcg
     1741 ccgacataac tttacagggg aaaggttgcc aaaaccgcgc cagtggctaa gataactcgc
     1801 gttaaacagt gagggcgcaa tggcgaaaca acaacggatg ggctggtggt ttctttgcct
     1861 tgcatgtgtc gtggtaatgg tttgtaccgc gcaacgcatg gcgggcctgc acgccttgca
     1921 gatgcaggcg acggcctctg ctgcggtggt cagcgctccc tcctcgacag atgacggctc
     1981 gccggtcact ccctgcgaat taagcgccaa gtcgctgctg gcggcgcctc cagtactctt
     2041 tgaaggtgct atccttgcgc tttatctact gctttcctta ctggcgcctg tccgggtcat
     2101 gcgcctgccg ttttcgcctc cacgggctat ttcgccgccc acattacggg tacatctacg
     2161 attttgtgtc ttccgtgaat gacagaccgg ttattactaa cggttaatta ctcattcacg
     2221 gagaaaaaat atgatgattt tattcaggcg gatactgttc tgcctgttat ggctttggct
     2281 gcccgtctcc tgggcggcgg aaagcggctg gctgcgttcg cccgataacg accatgccag
     2341 catacggcta cgtgccgata cgtccgctaa cagtgagacc cggctgttgc tggatgtcaa
     2401 actggaaaac ggctggaaaa cctactggcg cgcgccgggg gaagggggcg tggcaccctc
     2461 tatcgcctgg aaaggcgaca tgcctgaggt aagctggttc tggccaaccc cctcgcgctt
     2521 tgatgtggcg aatatcacca cccagggata tcacgacgag gtgacctttc cgatgatcgt
     2581 gcgcggtacg ccgccggcga ccttgcgcgg tgtgttgacg ttatcaacct gcagcaatgt
     2641 ttgtctgttg accgattacc ccttttccgt gacgcccact gtgcagaatg ccgattttgc
     2701 ccatgactat gcgcgggcga tgggtaaagt tccgctccgc agtgggctaa cggactcgct
     2761 tgacgttggc tatcgcccgg gagaactggt ggtcactgct acgcgagcgg cgggctggtc
     2821 atcgcccggg ctctatcttg acaccataga tgacgtcgat tttgcgaagc ctcgcctgcg
     2881 cgtagagggc gacaggttac aggcgacggt gccggtgacg gacagttggg gcgaaaaggc
     2941 gcccgatttg cgcgacaaat cgctgaccct cgtgttagcc gatggcgcta tcgcccagga
     3001 gagcacgcaa accattggcg ctgcgccagc gcaaacgccg gacaatgcgg cgctaccttt
     3061 ctggcaagtt gtaatgatgg cgctaatcgg cggactgatt cttaatttaa tgccctgcgt
     3121 actgcctgtt ctgggcatga aacttggctc tattttattg gtagaggaaa aaagccgctc
     3181 tcacatcagg cgacaatttt tggcttcggt cgccggtatc attgcgtcat ttatggcgct
     3241 ggcggcgttt atgaccctcc ttcgcctgtc aaaccatgcg ctggcctggg gagtccagtt
     3301 ccagaatgca tggtttattg gttttatggc gctggtgatg ttgttgttta gcgccagcct
     3361 gttcgggctt tttgagttca ggcttccctc atctatgacc acgaaactgg ccacttacgg
     3421 cggtaacggt atgtcgggac atttctggca gggggcgttc gccacgctgc tggcgacgcc
     3481 ttgtagcgcg ccgtttctgg gcacggcggt cgcggtggcg ctcacggcgt cgctgccgac
     3541 gctgtggggg ctgttccttg cgcttggcct gggaatgagc gcgccgtggc tactggtcgc
     3601 gatacgacca gggcttgcgc tacgtttacc gcgccccggg cgttggatga atgtcctgcg
     3661 caggatcctc ggtctgatga tgctggggtc ggctatctgg ctggcgacgt tactcctgcc
     3721 gcatttcggc ttcactgcgt caaagagcgc gcaagacacg gttcagtggc aaccgttgag
     3781 tgaacaggca atccagtcgg cgctggcgca gcataagcgg gtatttgtcg atgtcactgc
     3841 ggactggtgt attacctgta aagtgaataa atacaacgtc ctgcaaaaag aggatgtgca
     3901 ggccgccttg caacagccgg atgttgtggc gctgcgggga gactggacgc tgccgtccga
     3961 tgccattaca gattttctga aaacgcgcgg ccaggtcgcc gtgccgttta atcaggtata
     4021 tggccccggt ttgccggaag gggaggcact gcccactttg ctgacccgcg atgcggtatt
     4081 acaaacgttg aaaaaagcga aaggaataac ccaatgaaat acatgattgt tttactgctg
     4141 gcgctgtttt cgacgctgag catcgcgcaa gaaaccgctc cttttacgcc ggatcaggaa
     4201 aagcagatta aaaatctgat ccatgcggcg ttgtttaacg atcctgccag cccgcggata
     4261 ggcgctaaac accctaagct gacgctggtg aactttacgg attacaactg cccgtactgc
     4321 aaacagctcg atccgatgct ggaaaagatt gtgcagaaat atcctgacgt tgcggtcatt
     4381 attaaaccgc tgccattcaa aggagagagt tccatactgg cggcgcgtat tgcgctgacc
     4441 acctggcgcg atcatccgca acagttcctc gcgctacatg aaaaacttat gcaaaagcgc
     4501 ggttaccata cggatgacag tattaaacag gcccagcaga aagcaggggc gacgccagtg
     4561 acgctggatg aaaaaagcat ggaaacgata cgcactaatt tgcagttggc aagactggtc
     4621 gacgtgcaag gaacgccagc gacgatcatt ggcgacgagc tgattccggg cgcagtgccc
     4681 tgggatacgc tggaagcggt ggtgaaagaa aaactggcgg ctgccaatgg cgggtaaact
     4741 gcggcgttgg ctgcgtgaag ccgcggtttt tctggcgctc ctcatcgcga taatggtggt
     4801 catggacgtc tggcgcgcgc cgcaggcgcc tccggcgttt gccgcgacac cattacatac
     4861 gctgacggga gagtcgacaa ctctggcgac cttgagcgag gaacgccccg tactgctcta
     4921 tttttgggcc agctggtgcg gggtatgccg ctttaccacg cctgcggtcg ctcacctggc
     4981 ggcggaaggg gaaaacgtca tgaccgttgc gctccgctcc ggcggtgatg ctgaggttgc
     5041 ccgctggctg gcgcgcaagg gcgttgactt cccggtcgtc aatgatgcta acggcgcctt
     5101 atccgctggc tgggaaatca gcgtgacgcc aacgctggtg gtggtttcac aaggtcgggt
     5161 tgtgttcacc accagcggct ggaccagcta ttggggcatg aagcttcggc tgtggtgggc
     5221 aaaaacgttc tgaatatgcg ccggggtttc ccggcgctaa cgcgtttact gtaagaaaaa
     5281 cctccgtttt gcgaaatcgt tcccggaaaa atgatccatt tctgtcacac tcagaacgat
     5341 ttgataacaa caagaggtca tagggatgaa aaaatcatta ctcgctgttg ctgtggcagg
     5401 ggctgttttg ttgtcatccg ccgtacaggc gcagacaacg ccggaaggtt atcaattaca
     5461 acaggtgctg atgatgagcc gccataatct gcgggcgccg ctggcgaata atggcaacgt
     5521 actggcgcag tcgacgccga acgcctggcc ggcgtgggac gttcccggcg ggcaactgac
     5581 gacgaaaggc ggcgtgctgg aagtctatat gggacactac acacgtgaat ggctggtcgc
     5641 gcaggggctg ataccgtcgg gagaatgtcc ggcgcccgac acggtatatg cctatgcgaa
     5701 tagtttgcag cgcaccgtcg ccaccgcgca atttttcatt accagcgctt tccccggctg
     5761 tgatattcct gttcatcatc aggaaaaaat gggcactatg gaccctacct tcaatccggt
     5821 gattaccgat gattccgccg cgttccggca acaggccgta caggcgatgg aaaaggcgcg
     5881 tagtcagcta catcttgatg agagttataa actgcttgag cagataacgc attatcagga
     5941 ctcgccgtcc tgcaaagaga agcatcagtg ttcgctaatc gacgcgaaag ataccttcag
     6001 cgcgaactat cagcaagagc ctggcgtgca ggggccgctg aaagtaggga actcgctggt
     6061 ggatgcgttt accctgcaat attacgaagg ctttccgatg gatcaggtcg cttggggcgg
     6121 gatccacacc gatcggcagt ggaaggtgct gtcaaaactg aaaaacggct accaggacag
     6181 cctgtttacc tcacccacgg tggcgcgcaa tgtcgctgcg ccgctggtaa aatatatcga
     6241 taaggtgctg gttgccgagc gcgttagcgc gccgaaggtt accgtgctgg tggggcatga
     6301 ttccaatatc gcgtcgctgc tgacggcgct ggattttaaa ccctatcagc tccatgacca
     6361 gtatgagaga acgccgattg gtggtcagct tgtcttccaa cgctggcatg acggtaacgc
     6421 taaccgggat ttgatgaaaa tcgagtatgt ctaccagagc gcccggcagt tacgtaatgc
     6481 ggaagcgtta acgctcaaat cgcctgcgca aagggtaacg ctggaactga aaggatgtcc
     6541 ggtggatgcg aacggcttct gtccgctgga taagttcgat aacgtcatga acactgctgc
     6601 aaaatagccg tatgcccccg cgcaggcggg ggcgtttgtg ttatacgttc ttacgttcga
     6661 tgacttgttc gccccagaag agcgagtctt tgtccgtttt ctcaaaggct ttgatcagca
     6721 cctcatcgct accttcttcc catatttttt ctgccagttt ctcgtcatag tgagcgactt
     6781 caaaaatggc ttcggcaatt tccggcgacg tattacgcag gcttgcccat tcgccgacgc
     6841 ggtgcgcttt tgcttcttga gttggcattc gaatcctcct gttgaagatt agccgttgag
     6901 tttgactgcc agaccggcga cgtattcccc ctgatagcga gcgatagaga gttcctcctg
     6961 gcttggttga cgtgaaccgt cgcctccagc gatagtcgtt gcgccgtaag gcgtaccgcc
     7021 gcgaacctgg gagacgtcaa acagttcctg tgcggaatag cctatcggga caatcaccat
     7081 cccatgatgg gcaagcgtag tccaggtcga ggtgatggtc tgctcctggc cgccgcccgt
     7141 tccggtagaa ctgaacacgc cgccgagctt gccgtatagc gcgccggatg cccacagtcc
     7201 gccggtttgg tccaggaagg tacgcatctg gcctgacata ttgccaaacc gggttggcgt
     7261 accaaaaata atggcatcgt aatccgccag ctcctgtggg gtggcaaccg gtgcgttttg
     7321 cgttttaccg ccagcttttg cgaagatttc aggcggcatt gtttctggca cacgctttat
     7381 aatgacctct gcgccgtcga ctttctttgc cccttccgcc accgcgtgcg ccatggtttc
     7441 aatgtgtccg tacatggaat aatagagcac cagaatcttt gccatttgta ctactcctca
     7501 gattaatcag gtgtgtagcg attcgctacg tctatttaaa gatatgccct cctgtgaaga
     7561 gtgcaaattt cagcgccatt tctttgattt ataacaataa ttaatttggc gacctttgtt
     7621 gcaaaatgat acatttttaa gcgctttgat t
//
LOCUS       DAJVBX010000204         7642 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.204, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000204 DAJVBX010000000
VERSION     DAJVBX010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 7642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7642
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.204"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..711)
                     /locus_tag="OPV72_003852"
     CDS             complement(<1..711)
                     /locus_tag="OPV72_003852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916029.1"
                     /translation="MIKKSTYDVSHHSAICGVTGDYYRISATYHIKRSIRVFLIILCC
                     LLPGGVFAGSLINAGLISPDNVNLSIRDFLGFYASDNLQEKDNTLMYVLGVADATEGK
                     TWCGYGQVDSITINHTVLAWLDRYSVKKPDARASVLIEEALVKNFPCQGTEPSVKIAS
                     RSSPVLSLTPDALNLSGNDFFKFWVSGNQLDKLRAGIYLLGVEDATEKKLWCGYDLFK
                     TLTLNEIVYVFLKIKHIKN"
     gene            complement(716..2017)
                     /gene="tssL"
                     /locus_tag="OPV72_003853"
     CDS             complement(716..2017)
                     /gene="tssL"
                     /locus_tag="OPV72_003853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system protein TssL, long
                     form"
                     /protein_id="HCR9916030.1"
                     /translation="MTDSTLTPPAADMMSFLSTTPEHKDSEYETPVHTSQRTELNVIV
                     EDGPDSKLRLAEISAAANPLLAAARPLLCALAAMPAKLDAALVEPYRNLLVREMHLYQ
                     TLCDQANLRREHVLAVRYCLCTALDEAANNTTWGRRGVWAGKSLLVTFHGESEGGIKL
                     FQIIGRLAASFQEHGNVLEVIYHLLGLGFEGRYSVQPDGRKQLDNIRQQLLTQLSQRR
                     DPVMPALSPDFQGAISGRLRRMRRVPVWLSAGIALLAMLTLFGLYSHRMDVQTVTVQQ
                     HIDAIGIKLPPPVPVHKLRLKILLANEIARGLLTVDEDDQHSRVVFRGDAMFVPGQKT
                     VSDAIRPVINKAAREIARVGGAVTVTGHTDSQPIHSAEFPSNLVLSEKRAAEVAALLT
                     SGGVPAGRVHIVGKGDTVPVADNGSKAGRAKNRRVEILVVE"
     gene            complement(2014..3357)
                     /gene="tssK"
                     /locus_tag="OPV72_003854"
     CDS             complement(2014..3357)
                     /gene="tssK"
                     /locus_tag="OPV72_003854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssK"
                     /protein_id="HCR9916031.1"
                     /translation="MSWNDRVVWSEGQFLLPQMFQQQERYLEHVMHYRSLPLTPFFWG
                     FSHYNIDGEALNIGKLILKEASGIFPDGTPFNAPDHTPLPPPLTILPEHLNQQICLAV
                     PVRAPNSEETTFDNNPESLARFSVHEHDIRDANSLGRGAQLLQLSHLRLRLLPEKAVT
                     GAWIGLPLTRITGLNPDGRIDIDHDLIPPIINYQASSLMCTWLSWINDLIRMRADSLA
                     ERLTGSDNHGHEAAEVSDYLLLQILNRFEPLLTHLAKTPLAPEVLYRYLSELAGELST
                     YVRPQTRRPAEYKEYKHLTPYAGLKSLVDEVQFLLNAVLIRGAQRIELKEGTYGILNA
                     VVAPSDLADFSTLVLAIKASMPTDVLLQHFAAQTKIGPSDRLPELIRSHLPGLALQVL
                     PVPPRQIPFQAGYIYYDIRREGALWEHIARYGGMAMHTAGEFPGLETELWGVRDK"
     gene            complement(3361..3897)
                     /gene="tssJ"
                     /locus_tag="OPV72_003855"
     CDS             complement(3361..3897)
                     /gene="tssJ"
                     /locus_tag="OPV72_003855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system lipoprotein TssJ"
                     /protein_id="HCR9916032.1"
                     /translation="MNEWRNPTRWLCAVAMPFALLLLSGCGSSDALPDLESQRLDLSV
                     KASDKVNPDNQKKAAPIEIRVYELKNDAAFTTADYWSLHDNDKSVLTDDLVRRDSFIL
                     RPGEEKKLRRPLNAQTTAIGVLAGYRNLAKSVWRVTYKIPEAPEKAWYSSFIPGKGKV
                     QLEAELEQSAIVITERDK"
     gene            complement(3964..4449)
                     /locus_tag="OPV72_003856"
     CDS             complement(3964..4449)
                     /locus_tag="OPV72_003856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system tube protein Hcp"
                     /protein_id="HCR9916033.1"
                     /translation="MAYDIFLKIDGIDGESMDDKHKNEIEVLSWRWNIHQESTMHAGS
                     GLGSGKVSVTNLDFDHYIDRASPNLFKYCASGKHIPQAILVMRKAGGNPLEYLKYTFT
                     DLIVAVVSPSGSHDGEIASRETVELSFSTVKQEYVVQNQQGGSGGTITAGYDFKANKE
                     I"
     gene            complement(4686..5111)
                     /locus_tag="OPV72_003857"
     CDS             complement(4686..5111)
                     /locus_tag="OPV72_003857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001171576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916034.1"
                     /translation="MQKPILSLNSTCIVGGILWLLPVIVVHADEIVCPAVIHFSQAPI
                     ISSAEGWNVSSRAARMLNDGGFLSSGDPKEQADLKGEDAVVDGKKGHLWEIDPEDNRR
                     GIWFSCSYGQWAVLLARKVQGTVATCWSPDVLPAKLICK"
     gene            complement(5083..5484)
                     /locus_tag="OPV72_003858"
     CDS             complement(5083..5484)
                     /locus_tag="OPV72_003858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001147173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BPSL0067 family protein"
                     /protein_id="HCR9916035.1"
                     /translation="MPYVYANAKALQDTEKVGNHHQCVELIQHYIRVGQASTWQQGAA
                     VFGNKNIEVGTVIATFVNGRYPNHNSGNHAAFFLGQDTGGIWVMDQWKDDIAKPRVSK
                     RYIRKLHNGSVRSDGTYIRMSNNAEAYFIVE"
     gene            complement(5537..7045)
                     /gene="tssC"
                     /locus_tag="OPV72_003859"
                     /pseudo
     CDS             complement(5537..7045)
                     /gene="tssC"
                     /locus_tag="OPV72_003859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459271.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system contractile sheath
                     large subunit"
     gene            complement(7069..7611)
                     /gene="tssB"
                     /locus_tag="OPV72_003860"
     CDS             complement(7069..7611)
                     /gene="tssB"
                     /locus_tag="OPV72_003860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system contractile sheath
                     small subunit"
                     /protein_id="HCR9916036.1"
                     /translation="MAINNSAQKFIARNRAPRVQIEYDVEIYGSEKKIELPFVMAVLA
                     DLAGKPREELPPVTDRKFLDIDIDNFNERMKAIAPRVAFAVPNTLTGEGQLMVDITLE
                     NMDDFSPAQIARKVDALNQLLEARTQLANLQTYMDGKAGAENLVNKLLQDPTLLKTLA
                     NAPKSAATQQGVSADNESAE"
BASE COUNT         1720 a         2094 c         1913 g         1915 t
ORIGIN      
        1 gttctttatg tgttttattt ttaagaaaac atagacaatt tcatttaatg ttagcgtctt
       61 aaataaatcg tatccacacc atagtttttt ctccgttgca tcctccacgc caagcagata
      121 gatacccgcc ctgagtttat ccagttgatt accagatacc caaaatttaa aaaagtcatt
      181 acctgaaaga ttaagcgcat ccggcgtcag ggataacaca ggagatgacc gggaagcaat
      241 ttttacggag ggttcagtcc cctgacaggg gaaattttta actaatgctt cctctatcag
      301 caccgaagct cttgcatcag gctttttcac agagtaccga tcaagccagg ccagcacagt
      361 atggtttatt gttatactgt caacctgacc atatccacac cacgtcttac cttctgtggc
      421 atccgctacc cccaacacat acatcagtgt attatctttt tcctgtaagt tatcactggc
      481 ataaaacccc agaaaatccc gtatactgag gttgacatta tcgggggaaa ttaatcctgc
      541 gttaatcagg gacccggcaa aaacgccacc gggtaacagg caacataaga tgatcaaaaa
      601 aacacggata gatcgtttta tgtgatatgt cgctgagatc cgataataat cccccgtcac
      661 gccacatatt gccgaatgat gagacacatc ataggtcgat ttttttatca ttcattcact
      721 ccactaccag aatttccacc cgacggtttt tcgcccgccc ggctttactg ccgttatccg
      781 ccaccggcac cgtatcgccc ttgccgacga tatgtacccg tccggcaggt acgccgccgg
      841 aggtcagcaa cgccgcaact tccgccgccc gtttttccga tagcaccagg ttggatggga
      901 attcagccga atgaatgggc tggctgtcag tgtgacccgt tacagtgact gcgccgccca
      961 cgcgggcgat ttcccgcgcc gctttgttaa tcactggccg gattgcgtca ctcaccgttt
     1021 tttgtcccgg tacaaacatg gcgtcgccac ggaagaccac cctactgtgc tggtcatctt
     1081 cgtccacggt cagcaggcca cgggcgattt cgtttgccag caggattttc agccgcagct
     1141 tatgaaccgg cacgggcggc ggcagtttta taccaatcgc atcaatatgc tgttgtacgg
     1201 tgacggtctg cacatccatc cggtggctgt aaaggccaaa cagcgtcagc atcgccaaca
     1261 gggctatccc ggcgctcagc cagaccggca cccggcgcat ccgccgcagt cgtccgctta
     1321 tcgccccctg aaagtcaggc gagagcgcgg gcatgaccgg atcgcgacgc tgtgaaagct
     1381 gtgtcagcag ttgctgacga atattgtcca gttgcttacg cccgtctggc tgcacgctgt
     1441 agcggccttc aaatcccagc cccagcaggt ggtagataac ctccagtacg ttgccatgtt
     1501 cctggaagct ggccgccaga cgcccgatga tctggaaaag ttttatcccg ccttcgcttt
     1561 caccatgaaa tgttaccagc aggctttttc cggcccagac gccgcgccgc ccccaggttg
     1621 tgttattggc ggcttcatca agcgccgtac acaggcagta acgtaccgcc agtacgtgct
     1681 cgcgccgcag gttcgcctga tcgcataatg tctggtacag atgcatctcg cgtaccagca
     1741 gattacggta aggctctacc agggccgcat ccagtttagc gggcatggct gcgagagcgc
     1801 acaataaagg ccgggcagcg gcgagcaacg ggttagccgc cgcgctgatt tcagccagcc
     1861 ggagtttgct gtccggaccg tcttcaacga tgacattgag ttccgtgcgc tggctggtgt
     1921 gtaccggcgt ttcatattca ctgtccttat gttccggcgt ggtggacaaa aaggacatca
     1981 tgtccgccgc tggcggcgtc agggtactgt ctgtcattta tcgcgcactc cccacagttc
     2041 tgtctccagc cccggaaatt ccccggcggt atgcatggcc atcccgccgt aacgggcaat
     2101 gtgttcccac aatgctccct cgcggcggat gtcgtaatag atgtatccgg cctgaaacgg
     2161 gatttggcgc ggtggtacag gcagaacctg caaagccagc cccggcagat gcgagcggat
     2221 cagttccggc aggcgatcgg atggcccgat tttggtctgg gcggcaaaat gttgcagtag
     2281 cacatcggtc ggcattgaag cctttatcgc cagtaccagc gtgctgaaat cggcaagatc
     2341 ggaaggggcc accaccgcat tcaggatacc gtaagtcccc tctttcagct cgatgcgctg
     2401 cgcgccccgg atcagtaccg cgttcagcag gaactgcacc tcatcaacca gcgatttcaa
     2461 cccggcatag ggcgtcaggt gtttgtactc tttgtattca gcgggccgtc gcgtttgtgg
     2521 acgcacatag gtggagagtt ccccggccag ttcggacagg tagcgataca acacttccgg
     2581 ggccagcggg gttttcgcca ggtgagtcag cagcggctca aagcgattga gaatttgcag
     2641 cagcaggtaa tcggagacct ccgctgcttc atggccgtgg ttgtcgctgc cggtcagccg
     2701 ttccgccagc gaatcggccc gcatccggat gagatcgttg atccacgaca gccaggtaca
     2761 catcagtgaa ctggcctgat aattaatgat gggcgggatc aggtcgtggt cgatatctat
     2821 ccgcccgtca gggttcaacc cggtgatgcg ggtcaacggc aggccaatcc aggcgcccgt
     2881 caccgccttt tccggcagca gccgcaggcg cagatgactg agctgtaata actgcgcgcc
     2941 acgtcccagc gagttggcgt cgcggatgtc gtgttcatgt accgagaaac gcgccagtga
     3001 ttccgggtta ttgtcaaacg tggtttcttc gctgttcggc gcgcgtaccg gtaccgccag
     3061 acaaatctgc tggttcaggt gctccggcag gatggtcagc ggcggcggca gcggggtgtg
     3121 gtccggtgcg ttaaacggcg tgccgtcagg aaaaatccct gatgcctctt tcagtatcag
     3181 tttaccgatg ttcagcgctt cgccatcaat attgtagtgg ctgaatcccc agaaaaaggg
     3241 agtcagcggc aggctgcggt aatgcatgac gtgttccaga taacgctctt gctgctgaaa
     3301 catctgcggc agtaaaaatt gtccttcact ccagactacg cggtcattcc agctcataat
     3361 tcatttatcc cgttccgtaa ttacaatggc gctttgttcc agttccgcct ccaactgcac
     3421 ttttcctttc cccggtatga agctgctgta ccaggctttt tccggggctt ccgggatttt
     3481 gtaggttacc cgccagaccg atttggccag gttacggtat ccggccagta cgccgattgc
     3541 cgtggtctgc gcattcagcg ggcgacgcag ttttttctct tcgccgggac gcaaaataaa
     3601 gctgtcgcga cgcactaaat cgtcggtaag gacggatttg tcgttgtcat ggagcgacca
     3661 gtaatcagct gtcgtgaaag cggcgtcatt ttttagttca taaacacgta tctcaatggg
     3721 cgcggccttc ttctgattgt caggattcac cttatcggag gctttcacgc tcaggtcgag
     3781 tcgctgtgat tcgaggtcag gtaacgcatc gctactgccg catccggaaa gcaggagcag
     3841 tgcaaaaggc atagctaccg cacataacca ccgagtgggg ttacgccatt cattcactgt
     3901 aaattccttt aaaatcaaaa caataaatcc ggccagatat aaatctggcc ggaaaaacag
     3961 ccgttaaatt tctttgttcg ccttgaagtc gtaacctgcg gtgatagtgc cgccgctgcc
     4021 gccctgctgg ttctgcacca cgtattcctg tttcacagtg ctgaaagaaa gctcgaccgt
     4081 ttcacgggag gcgatttcac catcgtggct gccgctcggg gaaaccacgg cgacaatcag
     4141 gtcggtgaag gtatacttga ggtactccag cggattgccg ccagccttac gcataaccag
     4201 aatggcctgc ggaatgtgct tgccggaggc gcagtatttg aacaggttcg ggctggcgcg
     4261 atcgatatag tgatcaaaat ccagattagt gacggagacc ttaccggagc cgaggccgct
     4321 accggcgtgc atggtggatt cctgatgaat attccagcgc cagctcagta cttcaatttc
     4381 atttttgtgt ttgtcatcca ttgactcgcc atcaatgccg tcaattttta aaaaaatgtc
     4441 ataagccatt tttatatcct tattaagttt tacttaaaat aaacctggtt tatcctgata
     4501 atttgcgcag aaataaaccg ttgccgtaca gaatcccctt ccccgtaatt tcaggagaac
     4561 agaaggctgt ctttttccgc tgccaatatt attgaagtat ttacttcacg aataaatctt
     4621 aaacattaac aggcatcttt tatgcgtatt ctggcatcag agtattcata taaagattat
     4681 atattttatt tacaaatcaa tttcgccggt aagacatccg ggctccagca tgtcgcaacc
     4741 gttccctgaa cttttctggc aagcagaaca gcccactgtc cataactaca cgagaaccag
     4801 atcccccggc gattatcctc tgggtctatc tcccacaggt gccccttttt cccatcaacg
     4861 actgcatctt cacctttcag atctgcctgc tctttgggat cgccagacga aagaaaacca
     4921 ccatcattca acatacgcgc tgcacgggat gagacattcc atccttccgc tgaggaaatt
     4981 attggagcct gagaaaaatg aataaccgca gggcagacaa tctcatcggc atgaacaact
     5041 attaccggaa gtaaccacag aatgcccccg acaatacagg tgctattcaa cgataaaata
     5101 ggcttctgca ttattactca tccttatata agtcccgtca ctacgaacac ttccattatg
     5161 caactttctt atataacgtt tggacacacg gggttttgcg atatcatctt tccattgatc
     5221 catcacccat atcccgccag tatcttgccc caaaaaaaat gcagcatggt tgccactatt
     5281 gtggttcgga tatcgcccat tcacaaaagt agcgataact gtcccgactt caatgttttt
     5341 gtttccaaat actgcggccc cttgctgcca tgtactcgct tgtcctactc gtatatagtg
     5401 ttgaataagt tcaacacact gatggtggtt tcctaccttt tctgtatcct gtaaagcctt
     5461 tgcattagca taaacatatg gcatatattc tcttaatatc ctctgatatt atttatacat
     5521 tcacaaaata aatgcatcag gcattgccct gcttcactga cggcagtttt gtcaccaggc
     5581 gcagcgatcc tgtcagccct tcaagctgga aatgcggacg caggaagaat ttcgcgtcgt
     5641 aataacctgg attgccttcc acctcttcca ccactacctc cgcggcagcc agcggacgac
     5701 gggctttggt ttcttgcgag gagttcaccg gatcggcgtc gacataattc ataatccatt
     5761 catttagcca gcgctgcata tcctcgcgct ctttaaagga accgattttg tcgcggacga
     5821 tacatttgag gaagtgcgcg aagcgcgagc aggcgaacag gtacggcaga cgggcggaca
     5881 ggttagcgtt agccgtcgcg tccggatcgt agtattcctg tggtttttgc agcgattgtg
     5941 cgccgataaa ggcggcatag tctgagtttt tacggtggat caacgggata aaaccgtttt
     6001 tcgccagttc agcctcgcgg cggtcagaga tggcgatttc ggtcgggcat ttcatgtcca
     6061 cgccgccatc gtcagtcggg aaggtatggc agggaagatt ttccaccgca ccgcctgatt
     6121 ccacaccgcg aatcaacgta caccagccgt agtgtttgaa ggaacggttg atgtttacgc
     6181 ccatcgcgta ggccgcgttg ctccagacgt atttggtatg gtcagaacca tccgcatctt
     6241 cttcaaaatc aaactcgtcc accgggttgg tttttgcgcc atacggcagg cgggcaagaa
     6301 aacgcggcat cgtcaggcca atataacggg agtcttcgct agcccgcagc gagttccacg
     6361 gcgcatattc caggttctgg gtgacgattt tggtcaggtc gcggggattc gccagctcct
     6421 gccaggagtc catttgcagt accgaggggg aagccccggc aataaacggc gcatgggccg
     6481 acgcggcgac tttggcgata gagccaagca gatccacatc gggcggtgta tggtcgaagt
     6541 agtaatccgc aatgatacag ccataaggtt cgccgcctaa ctggccgtat tcggcttcat
     6601 acagtttctt gaacatcggg ctttgatccc aggcggtgcc cttgtaacgc ttcatgttgc
     6661 gccgcaattc atcttttgac agattcatga agcgaatttt cagcttttcg tcggtctcgg
     6721 tgttgtaaac cagatgctcc ataccgcgcc acgaggattc cagcttctgc cagtcgggat
     6781 gttgcaggat cagtttgatc tgttcggtca gtttaaagtc gatctgcgca ataatagcgc
     6841 tgatgctttt ataggcgtca tcgctgacgg tgatcgtgtt cgccagcgcc tgttgcgcca
     6901 gcgtctacac cgcggcttcc acagcttttg ccgcctgggt agtcttgggt cggaaggcct
     6961 gattcagcaa cgcatcaaat tcaccggatg cggagacggt atcctgagca accgcgtcgg
     7021 ttgcctgcat attactgttt gccatgaaaa ttccttaaaa attcgacatt attccgctga
     7081 ttcattatcc gctgacacac cttgctgggt agcggccgat ttcggcgcat tcgccagcgt
     7141 tttcagcaga gtcgggtcct gcaacagttt attgaccaga ttttccgccc cggccttgcc
     7201 atccatgtag gtctggaggt tcgccagttg agtgcgggct tccagtaact ggttcagggc
     7261 gtccaccttg cgggcaatct gtgccggcga aaagtcgtcc atattttcca gggtgatatc
     7321 gaccatcaac tgaccttcac ccgtcagcgt attcggcaca gcgaacgcca cgcgcggcgc
     7381 aatggctttc atgcgctcat tgaagttatc aatatcaata tcgaggaatt tgcgatccgt
     7441 caccggcggc agttcttcac gcggtttccc ggccagatcg gccagcaccg ccatcacgaa
     7501 cggcagctcg atttttttct cggaaccgta aatctctacg tcatattcaa tctgcacgcg
     7561 cggcgcgcgg ttgcgcgcga tgaatttctg cgcgctattg ttgatagcca taatccttca
     7621 tttccttttt agtcaactgg tt
//
LOCUS       DAJVBX010000205         7624 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.205, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000205 DAJVBX010000000
VERSION     DAJVBX010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 7624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7624
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.205"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..512)
                     /locus_tag="OPV72_003861"
     CDS             complement(<1..512)
                     /locus_tag="OPV72_003861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCR9916037.1"
                     /translation="MTLTQIHALLAVLEYGGFTEASKRLYMTQSAVSQAISALEEELG
                     VDILIRERRKEIELTAAGSRIVRHLRAIQRDVNAVKEIVEQEKKNPARTLRIGCFPSA
                     CACILPGVIRYFESHHPNVKIIPYEENSTAIIDSLQDGSIDAGFVPFPVNGMYCVPIY
                     RDKFTVVVPE"
     gene            674..1864
                     /locus_tag="OPV72_003862"
     CDS             674..1864
                     /locus_tag="OPV72_003862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR9916038.1"
                     /translation="MKEKLWTKDFWAITIVSFIIFFVFYVLLTLLPIYIADRLHASAD
                     KAGLLVTCFLAAAIVIRPFAGQWVGKYSNKKILVLSSLAFLVITALYPVCHSIESLLF
                     IRVLHGITFGVITTVKGTISARLIPASRRGEGISFFSLAMGLAMVVGPWIGLNMARWD
                     AFTAAFWLCSAVAALGIVLSLIVTVPPVIRHADGSKPNLGFSAMFDRAALPFALVTFF
                     MTFSYAGVSAFLALYARELDLMAAASNFLLCYAILLMICRTFTGNICDKKGPKYVVYP
                     CLLAFTIGLVALGYTNGSIMMIISGGLIGIGYGSVTPVFQTQIISSVEPHKIGVANSL
                     FFNAMDAGMAIGAFIMGMMVESVGYRMIYVAGAVLVVLAGALYAVQMKKRGVMPLVST
                     SELH"
     gene            complement(1866..2120)
                     /gene="yfaE"
                     /locus_tag="OPV72_003863"
     CDS             complement(1866..2120)
                     /gene="yfaE"
                     /locus_tag="OPV72_003863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-like diferric-tyrosyl radical
                     cofactor maintenance protein YfaE"
                     /protein_id="HCR9916039.1"
                     /translation="MGRVTLRITGTQLLCQDEHPSLLAALESHNVEVEYQCREGYCGS
                     CRTRLVAGQVDWITEPLAFIQPGEILPCCCRAKGDIEIEM"
     gene            complement(2120..3250)
                     /gene="nrdB"
                     /locus_tag="OPV72_003864"
     CDS             complement(2120..3250)
                     /gene="nrdB"
                     /locus_tag="OPV72_003864"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006683700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="HCR9916040.1"
                     /translation="MAYTTFSQTKNDQLKEPMFFGQPVNVARYDQQKYDIFEKLIEKQ
                     LSFFWRPEEVDVSRDRIDYQALPEHEKHIFISNLKYQTLLDSIQGRSPNVALLPLISI
                     PELETWVETWAFSETIHSRSYTHIIRNIVNDPAVVFDDIVTNEQIQKRAEGISAYYDE
                     LIEMTSYWHLLGEGTHTVNGKTVVVNLRELKKKLYLCLMSVNALEAIRFYVSFACSFA
                     FAERELMEGNAKIIRLIARDEALHLTGTQHMLNLLRSGVDDPEMAEIAEECKQECYDL
                     FVQAAQQEKEWADYLFRDGSMIGLNKDILCQYVEYITNIRMQAVGLDLPFQTRSNPIP
                     WINTWLVSDNVQVAPQEVEVSSYLVGQIDSEVDTDDLSNFQL"
     gene            complement(3363..5648)
                     /gene="nrdA"
                     /locus_tag="OPV72_003865"
     CDS             complement(3363..5648)
                     /gene="nrdA"
                     /locus_tag="OPV72_003865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /protein_id="HCR9916041.1"
                     /translation="MNQSLLVTKRDGRTERINLDKIHRVLDWAAEGLNNVSVSQVELR
                     SHIQFYDGIKTSDIHETIIKAAADLISRDAPDYQYLAARLAIFHLRKKAFGQFEPPAL
                     YHHVVKMVELGKYDNHLLEDYTEEEFKQMDSFIVHDRDMTFSYAAVKQLEGKYLVQNR
                     VTGEIYESAQFLYILVVACLFSNYPRETRLDYVKRFYDAVSTFKISLPTPIMSGVRTP
                     TRQFSSCVLIECGDSLDSINATSSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHT
                     GCIPFYKHFQTAVKSCSQGGVRGGAATLFYPMWHLEVESLLVLKNNRGVEGNRVRHMD
                     YGIQINKLMYTRLLKGGDITLFSPSDVPGLYDAFFADQDEFERLYVKYENDDSIRKQR
                     VKAVELFSLMMQERASTGRIYIQNVDHCNTHSPFDPVVAPVRQSNLCLEIALPTKPLN
                     DVNDENGEIALCTLSAFNLGAIKTLDELEELAILAVRALDALLDYQDYPIPAAKRGAM
                     GRRTLGIGVINFAYWLAKNGKRYSDGSANNLTHKTFEAIQYYLLKASNELAKEQGACP
                     WFNETTYAKGILPIDTYKKDLDAIVNEPLHYDWEQLRESIKTHGLRNSTLSALMPSET
                     SSQISNATNGIEPPRGYVSIKASKDGILRQVVPDYEHLKDAYELLWEMPNNDGYLQLV
                     GIMQKFIDQSISANTNYDPSRFPSGKVPMQQLLKDLLTAYKFGVKTLYYQNTRDGAED
                     AQDDLAPSIQDDGCESGACKI"
     gene            complement(6003..6731)
                     /locus_tag="OPV72_003866"
     CDS             complement(6003..6731)
                     /locus_tag="OPV72_003866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 3-demethylubiquinone
                     3-O-methyltransferase/2-octaprenyl-6-hydroxy phenol
                     methylase"
                     /protein_id="HCR9916042.1"
                     /translation="MNTEKPSVAHNVDHNEIAKFEAVASRWWDLKGEFKPLHRINPLR
                     LGYITERSGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESG
                     IEVEYVQETVEEHAAKHAQQYDVVTCMEMLEHVPDPQSVVHACAQLVKPGGEVFFSTL
                     NRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLSWVDETVLKEQHITGLHYNP
                     ITNTFKLGPGVDVNYMLHTRAKKA"
     gene            complement(6814..7509)
                     /locus_tag="OPV72_003867"
     CDS             complement(6814..7509)
                     /locus_tag="OPV72_003867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCR9916043.1"
                     /translation="MKNRLKRDFSHISIEIPKSITQVIKEKIREMIIHGDFDLGQAIS
                     ENELSNILMISKTPIREAFIWLSYNENLVNIIPRSGTFVFSVTDEDINDLIKMRVILE
                     QGAIREAMEKNANNVIVELSNILSKSAKINAERDTQAYLKLDHDFHYVFVKYADNKYI
                     SQAHLLISARLLAIRYRLDFTAEYITSSNRGHATILDMLKNNNVEGVCNFITHHIGSG
                     FTERARKLLALKA"
BASE COUNT         1748 a         1854 c         1950 g         2072 t
ORIGIN      
        1 ttttcaggca ccactacggt gaatttatcc cggtaaatgg ggacgcaata cataccgttg
       61 accggaaaag gaacgaaacc ggcatcaata cttccgtcct gcagcgaatc aataatagcc
      121 gtactgttct cttcataggg gataattttt acatttggat gatggctttc aaaatagcga
      181 atgacgccgg gtaaaatgca ggcgcaggcg ctgggaaaac agccaatccg tagcgtacgg
      241 gccgggttct ttttttcttg ttcgacaatc tcttttaccg cgttgacgtc gcgctggatc
      301 gcgcgtaagt gcctgacgat gcggctaccg gcggcggtaa gctcgatctc tttacgacgc
      361 tcacgaatca atatgtcaac gccgagctcc tcctcaagcg cggagatggc ctggctgacg
      421 gcggattgcg tcatgtatag ccgtttgctg gcctcggtaa atccgccgta ctccagtacg
      481 gcaagcaggg catggatttg ggttagcgtc attagtaaaa cctaatcaat ataattaaaa
      541 cgattaattt ttctaataaa gtgcacttgt ttatactgcg attctatcga atacatcaca
      601 ttttgacgca cctgataggt gttcagttga gctgagcgtt gcctgcgtgc gccatctgaa
      661 tgggtcgtta agaatgaaag aaaaattatg gacgaaggat ttttgggcaa tcaccatagt
      721 aagttttatt atcttttttg ttttttatgt actgctaact ttattaccca tttatatcgc
      781 tgaccgcctg catgcttctg cagataaggc aggattgcta gtgacatgtt tcctggccgc
      841 ggcaattgtt attcggccgt ttgccgggca gtgggtggga aaatattcga ataaaaagat
      901 tctggtgctc tcttctctgg cttttttggt gattaccgcg ctgtatccag tttgccattc
      961 tatcgagtcg ctgctcttta tccgcgtact tcatgggatt acgtttggtg ttattaccac
     1021 ggtaaaagga actatttcag cgcggttaat tccggcctcc cgacgtggag agggcatcag
     1081 ctttttctct ttagcgatgg gcctggcgat ggtcgtagga ccgtggattg gtttgaatat
     1141 ggcccgctgg gacgcgttca ctgccgcatt ctggctttgt tccgctgtag cggcgttagg
     1201 gattgtgctt tccctgattg tgacggttcc tccggtaatt cgtcatgccg atggttcgaa
     1261 accgaatctg ggtttttccg cgatgtttga ccgcgccgcc ttgccttttg cgctggtcac
     1321 cttttttatg actttctcct atgccggcgt gtcggctttc ctggcgctgt atgctcgtga
     1381 gctggattta atggcggcgg ccagtaattt cctgctgtgc tacgcgattt tactgatgat
     1441 atgccgtacc ttcaccggga atatttgtga taaaaaaggg ccgaaatatg ttgtttatcc
     1501 atgtctgttg gcttttacca tcggtctggt ggcgctgggc tacaccaatg gcagcatcat
     1561 gatgattatt tccggcggtc tcatcggtat cggctacggt tcggtcacgc cggttttcca
     1621 gacgcaaatt atcagctcgg ttgaaccgca taaaatcggt gtggcgaatt cactgttctt
     1681 taacgcgatg gacgccggaa tggcgattgg cgcctttatc atgggaatga tggttgagtc
     1741 ggttggctat cgtatgattt atgtcgctgg cgcggtgctg gtggtactcg ctggcgcact
     1801 gtatgccgtg cagatgaaaa aacgtggcgt gatgccgttg gtttccacca gcgagttgca
     1861 ctgagttaca tctcgatttc gatatcgcct tttgccctgc agcagcaggg caaaatctct
     1921 cccggctgga taaacgctaa aggttccgta atccagtcaa cctgaccggc aaccagccgg
     1981 gtacgacagg agccgcaata tccttcgcgg cactgatact ccacctcaac gttatgcgat
     2041 tccagcgcgg ccagcagaga agggtgttca tcctggcaca gcagctgtgt gccagtgata
     2101 cgcagcgtga cgcgtcccat cagagctgga aattactcag atcgtcggta tcgacttccg
     2161 aatcgatttg tccgaccaga taagaactaa cttccacttc ctgtggcgca acctgaacgt
     2221 tatcggacac cagccaggta ttgatccacg ggattgggtt ggagcgggtc tggaacggca
     2281 gatccagacc cactgcctgc atacgaatat tcgtaatata ttcaacgtat tgacacagga
     2341 tatctttatt caggccgatc atcgaaccgt cgcggaacag atagtccgcc cactcttttt
     2401 cctgctgcgc cgcctgcacg aacaggtcat agcattcctg tttacactct tcggcgattt
     2461 ccgccatctc cgggtcgtcc acgccgctac gcaacaggtt cagcatatgt tgcgtgccgg
     2521 tcagatgcag cgcttcgtca cgggcgatca gacggataat tttggcgttg ccttccatca
     2581 gttcacgctc ggcaaatgcg aaagagcagg cgaagctgac gtagaagcgg atggcttcca
     2641 gcgcgttcac gctcatcagg cacagataca gttttttctt cagctcacgc agattcacga
     2701 caaccgtttt gccattaacg gtatgggtgc cttcaccgag cagatgccag taactggtca
     2761 tctcaataag ttcgtcgtag taggcggaga taccttcggc gcgcttctga atttgctcat
     2821 tggtcacgat atcgtcaaac acgaccgccg gatcgttgac gatgttacga ataatgtggg
     2881 tgtaggatcg tgagtgaatc gtctcagaaa acgcccaggt ctctacccac gtctccagct
     2941 ccgggatgga aatgagcggc agcagggcga cgttcgggct acgtccctga atggaatcca
     3001 gcagcgtctg gtatttgagg ttgctgatga agatatgttt ttcgtgctcc ggcaacgcct
     3061 gatagtcgat acgatcgcgg gagacgtcga cctcttccgg acgccagaag aaagagagct
     3121 gtttttcgat cagtttttcg aagatgtcat atttctgctg gtcatagcgt gcaacgttga
     3181 ccggctggcc aaagaacatg ggttccttga gctgatcgtt tttcgtttgt gaaaaagtgg
     3241 tgtatgccat tgaagtgaat cctttatggg atgagcgccg gatggcggcg caagcgcctt
     3301 atccggccta caaaccgtac aatcgtaggc cgggtaagca tagcgctacc cggcactatt
     3361 catcagatct tacaagcgcc gctttcgcag ccatcgtcct gaatagaagg cgccaaatcg
     3421 tcctgcgcat cttccgcgcc gtcgcgggta ttttgatagt acagagtttt cacgccaaac
     3481 ttatacgcgg tgagcaaatc tttcagcagt tgctgcatcg gcacttttcc tgacgggaaa
     3541 cgtgacggat cgtagttggt attagcggaa atcgactggt cgataaactt ctgcatgata
     3601 cccaccagtt gcagataacc gtcgttgttc ggcatctccc acaacagttc gtaagcgtct
     3661 ttcagatgct cataatccgg cacgacctga cgcaaaatac cgtctttcga ggccttgatg
     3721 ctgacgtagc cgcgcggtgg ttcgataccg ttggtggcgt tggagatctg ggatgacgtt
     3781 tccgacggca ttagcgccga tagcgtggag ttacgcagac cgtgggtttt gatcgactca
     3841 cgcagctgtt cccagtcgta gtgcagcggt tcgttgacga tcgcatccag atcttttttg
     3901 taggtgtcga tcggcaaaat gccttttgca taggtggttt cgttgaacca tgggcaggcg
     3961 ccttgctctt tcgccagttc gttggacgct ttaagcagat agtactgaat ggcttcgaag
     4021 gttttatgcg tcagattatt ggcgctgccg tcggaataac gtttaccgtt tttcgccagc
     4081 cagtaggcga agttaatcac gccaatgccc agcgtacgac ggcccattgc gccgcgtttg
     4141 gcagccggaa tcgggtaatc ctgataatcg agcagagcat ccaaagcgcg tactgccaga
     4201 atagccagtt cttccagctc gtccagagtc ttaatggcac ccaggttgaa ggcagacagc
     4261 gtacacaacg caatttcgcc gttttcatcg ttgacatcgt tcagcggttt ggttggcagg
     4321 gcaatctcca gacacaggtt agactggcgt accggggcga caaccggatc gaacggactg
     4381 tgagtattgc agtggtcaac gttctggata tagatacgac cggtagaggc gcgttcctgc
     4441 atcatcagcg agaacagttc gaccgctttc acacgctgtt tgcggatgct gtcgtcgttt
     4501 tcatacttca cgtacaggcg ttcgaattcg tcctggtcgg cgaagaatgc atcgtatagc
     4561 ccgggtacat cggacggact gaacagcgta atgtcgccgc ccttcagcag gcgggtgtac
     4621 atcagtttgt tgatctgtat gccgtagtcc atgtgacgta cgcggttgcc ttccacgcca
     4681 cggttgtttt tcagcaccag caggctttcc acttccagat gccacatcgg gtagaacagt
     4741 gtcgccgcgc cgccgcgcac gccgccctgc gagcaggatt tcaccgccgt ctggaagtgc
     4801 ttgtagaacg gaatacagcc ggtgtggaac gcctcgccgc cacgaatcgg gctacccagc
     4861 gcacgaatgc ggccagcgtt gatgccgata ccggcgcgct gggaaacgta tttcacaatc
     4921 gcgctggagg tggcgttgat ggaatccaga ctgtcgccac actcgatcag tacgcaggag
     4981 ctgaactgac gggtcggggt acgcacgccg gacatgatgg gcgtcggcag cgagattttg
     5041 aacgtagaga ccgcatcgta aaaacgtttt acatagtcaa gacgcgtttc acgcggatag
     5101 ttagagaaca ggcaggccac taccagaatg tagaggaact gcgcgctttc atagatttcg
     5161 ccggtcacgc ggttttgcac cagatatttc ccttccagct gcttaacggc agcgtaggag
     5221 aaggtcatat cgcgatcgtg aacgataaac gaatccatct gcttgaactc ttcttccgtg
     5281 tagtcttcca gcagatgatt gtcgtatttg ccaagctcaa ccatttttac cacatggtgg
     5341 taaagtgcgg gcggctcaaa ctggccgaag gctttcttac gcaggtggaa aatcgccaga
     5401 cgcgcagcca ggtattgata atccggcgca tcgcgagaga tcaggtctgc ggcggcctta
     5461 atgatagttt catggatatc ggaggtctta atcccatcat aaaactgaat atgcgagcgt
     5521 agctcgacct gagaaaccga tacgttattc agtccttctg ccgcccaatc aagcacgcga
     5581 tgaattttgt cgagattgat gcgctcagta cggccgtcac gctttgtcac cagcagactc
     5641 tgattcatgt agttttctac ctgtttacct gtccgtgaaa gaaaaatatc ccccccgctt
     5701 atccacaacg ccacgttgtg actaactctg tggataaata ctatatatag ggggtaatcg
     5761 ataagtgaaa cgctatatgg tgagtattct agtagggatt cttttgagta caagagttga
     5821 ttttggcgtt aaattgcggt tgtaaaagag taagaatcgc taaatgcgcg tctgataagg
     5881 cctggagagg atgtcaacaa ttcataaaaa aatcaaaatt tgatcgaatg ctgatttttt
     5941 catcgaagag aaaggttgcg cccgatgatc taacgcaacc cttataggaa aattctttga
     6001 tgtcaggctt ttttagcgcg ggtatgcaac atgtagttaa cgtctactcc gggaccgagt
     6061 ttgaaagtat tggttatcgg gttgtagtgc agcccggtga tatgttgctc tttcaggacg
     6121 gtttcatcta cccagcttaa cagttcagca ggcttaatga atttcttcac gtcgtgcgtg
     6181 ccttttggca ccatgcgcag aatatactca gcgccgacga ccgccatcag ccaggatttc
     6241 ccattgcggt tcaacgttga gaagaacacc tcgccgccgg gtttaaccag ttgggcgcag
     6301 gcgtggacga ccgattgcgg atcgggaacg tgctccagca tttccataca ggtgacgacg
     6361 tcgtattgct gggcgtgttt tgccgcatgt tcctcaaccg tctcctgcac gtactctacc
     6421 tcaatgccgc tttccagcgc atgcagtttg gcgacctgca aaggctcaaa gcccatatcc
     6481 agcccggtaa cggtagcgcc ttcgcgcgcc atgctctccg ccagaatacc gccgccacag
     6541 ccgacgtcga gcaccttttt accgaacagg ccgcctgagc gctcagtaat gtagccaagg
     6601 cgtagggggt tgatgcgatg caatggcttg aattcgccct tcagatccca ccagcgcgac
     6661 gcgacggctt cgaatttggc gatttcatta tggtcaacgt tgtgagctac cgacggtttt
     6721 tcagtgttca tgagtacatg agattccgct attgatctat cggggcagta tagcaggtgc
     6781 aaagtcgctg cgttatatct actgccgtct ttattacgct ttcagcgcaa gaagttttct
     6841 tgcgcgttct gtaaaaccgc taccgatgtg gtgcgtgata aaattacaga cgccctcgac
     6901 gttgttgttt tttaacatat ctaaaatagt ggcatgtcca cggttagagc tggtgatata
     6961 ttcagcggta aaatccagtc tgtagcgaat tgccaataaa cgtgcagaga tcaacaggtg
     7021 tgcttgtgaa atgtatttat tatcggcata tttcacaaaa acataatgaa aatcatgatc
     7081 cagtttgagg taagcttgcg tatctcgctc tgcattaatt tttgctgact tcgataaaat
     7141 attgcttaat tcgactatga cattgttagc atttttctcc atcgcttcac gaattgcgcc
     7201 ctgttcaagg ataaccctca ttttgatgag atcattgata tcctcgtcgg tgacagaaaa
     7261 aacaaatgtc ccactgcggg gaatgatgtt gaccaggttt tcattatagc tcagccaaat
     7321 aaaagcttca cgaattggtg ttttacttat catcagaata tttgatagtt cattttcact
     7381 gatcgcttgc ccaagatcga aatcgccatg gataatcatc tcccttattt tctctttaat
     7441 cacctgggtg atggatttgg gtatttcaat tgatatgtga ctaaaatcac gctttaatct
     7501 atttttcatt ttcttctcct ccatggttaa acccggctcc attgtaatta atttattcaa
     7561 aattaacgga tctaatatat cagatataag aaaatttaca tactttattg ttgttattgt
     7621 atat
//
LOCUS       DAJVBX010000206         7594 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.206, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000206 DAJVBX010000000
VERSION     DAJVBX010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 7594)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7594)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7594
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.206"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            162..377
                     /gene="bdm"
                     /locus_tag="OPV72_003868"
     CDS             162..377
                     /gene="bdm"
                     /locus_tag="OPV72_003868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-dependent modulation protein"
                     /protein_id="HCR9916044.1"
                     /translation="MFTYHSANTSAAQPALVNAIEQGLRAELGVVTEDDILMELTKWV
                     EASDNDILSDIYQQTINYVVSGQHPTL"
     gene            472..615
                     /gene="sra"
                     /locus_tag="OPV72_003869"
     CDS             472..615
                     /gene="sra"
                     /locus_tag="OPV72_003869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stationary-phase-induced ribosome-associated
                     protein"
                     /protein_id="HCR9916045.1"
                     /translation="MKSNRQARHILGLDYRISNQRKVVTEGDTSSVVNNPTGRKRRAD
                     SQK"
     gene            792..2489
                     /locus_tag="OPV72_003870"
     CDS             792..2489
                     /locus_tag="OPV72_003870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HCR9916046.1"
                     /translation="METTTKKARSLYIPYAGPVLLEFPLLNKGSAFSVEERRNFNLSG
                     LLPEVVESIEEQAERAWLQYQGFKTEIDKHIYLRNIQDTNETLFYRLVQNHLEEMMPV
                     IYTPTVGAACERFSEIYRRARGVFISYPNRHNMDDILQNVPNHNIKVIVVTDGERILG
                     LGDQGIGGMGIPIGKLSLYTACGGISPAYTLPVVLDVGTNNQQLLNDPLYMGWRHPRI
                     TDDEYYAFVDEFIQAVKQRWPDILLQFEDFAQKNAMPLLTRYRDEICSFNDDIQGTAA
                     VTVGTLIAASRAAGSQLSEQKIVFLGAGSAGCGIAEQIIAQTQREGLSEDAARQNVFM
                     VDRFGLLTDRMPNLLPFQAKLVQKCDNLQHWDTENDVLSLLDVVRNVKPDILIGVSGQ
                     TGLFTEEIIREMHKHCPRPIVMPLSNPTSRVEATPQDIIAWTEGNALVATGSPFSPVI
                     WKDKVYPIAQCNNAYIFPGIGLGVIASGASRITDEMLMSASETLAKHSPLVNNGEGLV
                     LPALKDIQVVSRAIAFAVGKMAQQQGVAVKTSAEALQQAIDDNFWKPEYRDYRRTSI"
     gene            2771..3781
                     /gene="adhP"
                     /locus_tag="OPV72_003871"
     CDS             2771..3781
                     /gene="adhP"
                     /locus_tag="OPV72_003871"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HCR9916047.1"
                     /translation="MKAAVVTQDHQVDVTEKTLRPLRHGEALLKMECCGVCHTDLHVK
                     NGDFGDKTGVILGHEGIGVVAEVGPGVTSLKPGDRASVAWFYEGCGHCEYCNTGNETL
                     CRNVKNAGYTVDGGMAEECIVVADYAVKVPEGLDSAAASSITCAGVTTYKAVKISHIK
                     PGQWIAIYGLGGLGNLALQYAKNVFNAKVIAIDVNDGQLKLAEEMGADLTINSRTEDA
                     AKIVQEKTGGAHAAVVTAVAKAAFNSAVDAVRAGGRVVAVGLPPEAMNLDIPRLVLDG
                     IQVVGSLVGTRQDLTEAFQFAAEGKVVPKVALRPLEDINVIFKEMEQGQIRGRMVIDF
                     RR"
     gene            complement(3774..4904)
                     /locus_tag="OPV72_003872"
                     /pseudo
     CDS             complement(3774..4904)
                     /locus_tag="OPV72_003872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460529.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
     gene            5020..5398
                     /locus_tag="OPV72_003873"
                     /pseudo
     CDS             5020..5398
                     /locus_tag="OPV72_003873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460532.3"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GFA family protein"
     gene            complement(5423..6910)
                     /gene="smvA"
                     /locus_tag="OPV72_003874"
     CDS             complement(5423..6910)
                     /gene="smvA"
                     /locus_tag="OPV72_003874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl viologen efflux MFS transporter SmvA"
                     /protein_id="HCR9916048.1"
                     /translation="MFRQWLTLVIIVLVYIPVAIDATVLHVAAPTLSMTLGASGNELL
                     WIIDIYSLVMAGMVLPMGALGDRIGFKRLLMLGGTLFGLASLAAAFSHTASWLIATRV
                     LLAIGAAMIVSATLAGIRATFCEEKHRNMALGVWAAVGSGGAAFGPLIGGILLEHFYW
                     GSVFLINVPIVLVVMGLTARYVPRQAGRRDQPLNLGHAVMLIIAILLLVYSAKTALKG
                     NLSLWVISLTLLTGALLLGLFIRTQLATSRPMIDMRLFTHRIILSGVVMAMTAMITLV
                     GFELLMAQELQFVHGLSPYEAGVFMLPVMVASGFSGPIAGALVSRLGLRLVATGGMAL
                     SALSFYGLAMTDFSTQQWQAWGLMALLGFSTASALLASTSAIMAAVPAEKAAAAGAIE
                     TMAYELGAGLGIAIFGLLLSRSFSASIRLPAGLEAQEIARASSSMGEAVQLANSLPPT
                     QGQAILDAARHAFIWSHSVALSSAGSMLLLLAVGMWFSLAKAQRR"
     gene            7028..>7594
                     /locus_tag="OPV72_003875"
     CDS             7028..>7594
                     /locus_tag="OPV72_003875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HCR9916049.1"
                     /translation="MSYLNRDERREVILQAAMRVALAEGFAAMTVRRIASEADVAAGQ
                     VHHHFSSAGELKALAFVHLIRTLLDAGQVPPPATWRARLHAMLGSEDGGFEPYIKLWR
                     EAQILADRDPHIRDAYLLTMQMWHEETVTIIEQGKQAGEFTFTANATDIAWRLIALVC
                     GLDGMYVLGIPEMADPAFKYHLDRMITLE"
BASE COUNT         1840 a         2025 c         1994 g         1735 t
ORIGIN      
        1 ataatatatt ttcttctggg gtaaacaatt agagttccgc cttgcgttaa aataactcca
       61 ggactaatct taaccacagc cgcaaaaata tttgccatgc tgaatacgaa ttaattttct
      121 gcgagccgta ctaaataaat acatgttcac ggaggcatta tatgtttact tatcactcag
      181 caaatacctc agcagcacaa ccggccctgg tcaacgcgat tgaacaagga ttacgcgcgg
      241 agttaggcgt tgtcactgaa gatgatattt taatggagct gaccaaatgg gttgaggctt
      301 ccgacaatga catcctcagt gacatctacc agcagaccat caactatgtg gtaagcgggc
      361 agcacccgac tctgtaaaac ctgctatgct gtatcggcaa ccttaggggt tacgtttctt
      421 tcgcgtaagc gaatttgtcc ttaaaactag caacaggatt gaggagttaa catgaaatcg
      481 aaccgtcagg ctcgtcatat acttggactg gattacagaa tttccaacca gcgtaaggtt
      541 gttactgaag gcgacaccag cagcgtggtg aataacccaa ccggcagaaa gcgtcgcgcc
      601 gatagccaaa agtaatcgta cagtcctgaa atgacgttaa acaccattgc atctgcaatg
      661 gtgtttttgt ttataggaat gaccttaacg tctcacaatg ctttatactc agggtcggtt
      721 ccctggtgga aggcaatata tgatgataaa cgacggtgcc agggacagtt attcgaaaaa
      781 gagtgagcaa catggaaact acaaccaaga aagcacgttc cctttatatc ccttacgctg
      841 gccctgtatt gctggaattc cccctgttaa acaaaggcag cgcttttagc gtagaagagc
      901 gccgcaactt caatttgtca ggactgctgc cggaggtcgt cgagtcgatt gaagaacagg
      961 ccgaacgcgc ctggctccag tatcaggggt ttaaaacaga aatcgataag catatttacc
     1021 tgcgtaacat ccaggatacc aacgaaacgc tcttttatcg actggtgcaa aaccatcttg
     1081 aagagatgat gccggttatc tataccccga ccgtgggcgc ggcctgtgag cgcttctctg
     1141 agatttatcg ccgggcgcgc ggcgtattta tctcttatcc gaaccgtcac aatatggacg
     1201 acattttgca gaatgtgcct aaccacaaca ttaaagttat tgtggtgacg gatggcgagc
     1261 ggattctggg gcttggcgat cagggcatcg gcggaatggg gatacctatc ggtaagctgt
     1321 cattatacac cgcctgcggc ggcattagtc cggcctatac ccttcccgtt gtgctggatg
     1381 tcggcaccaa caatcaacag ttactcaacg atccgctcta catgggctgg cgtcatccgc
     1441 gcattaccga cgatgagtat tatgcgtttg tcgatgagtt tattcaggcc gttaagcagc
     1501 gctggccaga tatcctgcta cagttcgaag atttcgcgca gaaaaacgca atgccgctgt
     1561 tgacgcgcta tcgtgatgag atttgctcct ttaacgatga tattcagggc accgcagccg
     1621 tgaccgtcgg tacgttgatc gccgccagcc gcgctgccgg cagtcagctt agcgagcaga
     1681 aaatcgtttt cctcggcgcg ggttcagccg gatgtgggat tgctgaacag atcatcgcgc
     1741 agactcagcg tgaaggttta agcgaagatg ccgctcgaca gaacgttttt atggtcgatc
     1801 gcttcggcct gttgacggac cggatgccta atttattgcc gttccaggca aaactggtgc
     1861 agaaatgcga caatctccag cactgggata ccgaaaatga cgtgctgtcg ctgctggatg
     1921 tggtgcgtaa cgtgaagccg gatatcctga tcggggtttc cggccagacc gggctcttta
     1981 ctgaagagat catccgcgag atgcataagc attgccctcg cccgatcgtc atgccgctct
     2041 ctaatcccac ctctcgcgtg gaggccacgc cacaggacat tatcgcctgg acggaaggca
     2101 acgcgctggt ggcaaccggc agcccattct cgccggtcat ctggaaagat aaggtttatc
     2161 cgatcgcaca atgtaataac gcctatattt tccccggcat cggacttggg gttatcgctt
     2221 ccggcgcatc gcgcattact gatgaaatgc tgatgtcagc cagtgagacg ctggcgaaac
     2281 attctccgct ggtgaataac ggcgaaggat tagtgttacc agcgcttaaa gacatccagg
     2341 tcgtgtcgcg cgctatcgct tttgccgtag gcaaaatggc gcagcaacaa ggcgtagcgg
     2401 tgaaaacctc tgcggaagcg ctgcaacagg cgattgacga taacttctgg aaaccggaat
     2461 accgcgacta ccgtcggact tccatttaat acgtacccgg cggtgaatgc cgccggatat
     2521 cactttcttc tttagttttg gtgagtctgt cgacacacct gaattccttt ccctgcttat
     2581 ttgtcaagct actaatatta gccaccttta tgtattgaac gaggatttat caggataatc
     2641 ctggctaaac tattacattg tatttctgcc gccttgcata actcatcaga aatattaatc
     2701 ctaaagaggt aatagcacct tacctgctat tacctgctat gcagttcact attaagaaaa
     2761 ggagaaggtt atgaaagctg ctgttgtcac acaagatcat caggttgatg ttactgagaa
     2821 aacgctgcgt ccccttcgcc acggtgaagc tttgctaaaa atggagtgct gcggtgtatg
     2881 ccataccgat ctacacgtga aaaacggaga tttcggtgac aaaaccggcg ttattctggg
     2941 acacgaaggc attggcgtcg tggcggaagt cggtcctggt gtcacctcgc tgaaacccgg
     3001 cgatcgcgcg agtgtcgcgt ggttttatga aggatgcgga cactgtgagt attgcaatac
     3061 gggcaatgaa accttatgcc gcaacgtgaa aaatgccggt tacacggtag atggcggcat
     3121 ggccgaagag tgtattgtcg tcgcggatta tgcggtgaaa gtaccggaag gcctggactc
     3181 tgcggcggca agtagtatta cctgcgcggg cgttaccacc tataaagcgg tgaagatttc
     3241 tcatattaaa cctggccagt ggattgccat ctacggtctg ggcggtctgg gtaatctggc
     3301 cttgcagtac gcgaaaaacg ttttcaatgc gaaagtgatc gccattgatg tcaatgatgg
     3361 gcaactgaaa ctggccgagg aaatgggcgc agatctgacc attaattcac gtacggaaga
     3421 tgcggctaaa attgtgcagg aaaaaaccgg tggcgcgcac gcagcggtgg ttaccgcggt
     3481 cgctaaggcg gcgtttaatt ccgcagtaga tgccgttcgc gccggaggcc gcgtggtggc
     3541 agtcgggctg ccgccagaag ccatgaacct tgatatccct cgcctggtgc tggatggcat
     3601 tcaggttgtc ggttcgttgg tggggacacg ccaggatctg accgaagcct tccagttcgc
     3661 ggcggaagga aaagtcgtgc caaaagtcgc tttacgtccg cttgaagata tcaacgttat
     3721 ttttaaagag atggaacagg gacaaattcg tggccgtatg gtcatcgatt tccgtcgtta
     3781 aacgatttgc tgtggttctg ccagaacgtt gacgtttcag tcaccagcgg atcgataacg
     3841 accagatact tcagtttgct taagctttgc accactttgt ttttgtccgg gaaggacgcc
     3901 accgggttaa agccctgaca gaaatagccg gtaactttcc cgctatccat catgttgaaa
     3961 tatttgatca catcatagga ctgatcccac ttaggcagcc aggcaaagcc ccagtcattc
     4021 tctttctgcg ccgcatcgcc atagaaagat ttcatcaggc tgacgaagaa cttaggataa
     4081 ttcccccagt agttgacctg atcggccagc gtcgctttgg gggtattcgc ggccagataa
     4141 gtttgcagat cggcctgttt ttctgacggt agcgtcaggt agcccggcag gctggtggag
     4201 agcagtccta aatccgttaa gccctgaata ttagagtggc cgcgcaaggc gttcacaccg
     4261 ccgccagcca tccccatatt gccgagcagc aactggatca tcgccatagt acggatgttc
     4321 tgcgccccga cggtatgttg cgtccagccc agcgcataca ggaaggtcgt agtgcgatcc
     4381 ggcgcgctgg tagaggccaa cacctcacac accttcagga agtccgcttt cggcgtaccg
     4441 cagatgtttt ccacgacgtc cggcgtatag cgcgaaacgt gctgcttcag cagattccac
     4501 acacagcgtg ggtgcgtcaa cgtttcatca cgtttggcat agccgttttc atcgaactgg
     4561 tagttccagg aggatttatc gtactgacgc ttttgggcgt catagccgct gaaaagaccg
     4621 tcttcgaacg taaagtcttc ccgcaccagc aggctggcgt tggtgtaatg cttaacgtat
     4681 tcagcgttga ttttgttatt ttcgatcagg tacagcaaaa cgccggacag aaaggtaatg
     4741 tctgtaccgg aacgtattgg cgcatagata tccgccaccg acgccgtacg cgtaaagcgt
     4801 ggatcaacga caatcagcgt cgcatcgtta ttatttttcg cttccatcgc ccagcggaaa
     4861 cccaccggat gcgcttctgc ggcattgccg cccatcacca tcagtccttt cagggctggc
     4921 tttttctctt gatgtagact cggtcataag gagtatgccg tgcagacgtt cactggtcgt
     4981 tgtctttgcg gacaaagcca ttttaccgtt gacgtcgaaa tgctggatgt ctatgcctgc
     5041 cattgtacgc tgtgtcaaaa atggtcgggt ggaatagcca tgtatctgga agcctgcggg
     5101 caaccacagc tagcccccct ttccccggaa ccgccatact tttcatcctc ttcgcgcggc
     5161 gaacgctact tctgttctgg ctgcgggtgt ccgctgtggt ttcggcttac cgataccgat
     5221 cgctattttt ccctggacct tactggaact gaacgaagtt gatcgccgtc ggctgattct
     5281 ggctgcggaa atttataccg aaacccagcc tgccttctgg cgactgacgg ggcaatacgc
     5341 acgcctcagc ggtaaagagg ttgaggaaat ggactccccc tgccagctag cgcattaagc
     5401 gcttatctca tcaggcgtta tgttatcggc gttgggcttt tgccaggctg aaccacatcc
     5461 ctaccgccag caaaagaagc atactcccgg cgctgcttaa cgccacgcta tgcgaccaga
     5521 taaaggcgtg tctggcggcg tccagtattg cctgcccctg cgtgggcggc aggctattcg
     5581 ccaactgcac ggcttctccc attgaagatg acgctctggc aatctcttgc gcctcaagcc
     5641 cggcaggcag acggatagac gcggagaagc tacggcttaa caacaggccg aaaatggcga
     5701 tgcccagtcc cgcgcccagt tcataagcca tcgtttctat cgcgccggcc gccgccgctt
     5761 tttctgccgg cacagcggcc ataattgccg acgtggaagc cagcaatgcg ctggcggtgc
     5821 taaatcccag cagcgccatc agcccccagg cctgccattg ttgggtgctg aaatccgtca
     5881 tcgccagacc ataaaaactc agcgcgctta acgccatgcc gcccgtcgcg accagccgta
     5941 accccagacg cgagaccagc gcgcccgcaa tcggcccgct gaatccactg gcgaccatca
     6001 ccggcagcat aaataccccg gcctcataag gcgatagccc gtgaacaaac tgtagctctt
     6061 gcgccatcag cagctcaaaa cccaccagag tgatcatcgc ggtcatcgcc atcacgacgc
     6121 cgctcaggat aatgcgatgg gtaaatagtc gcatatcaat catcggacgc gatgtcgcaa
     6181 gctgtgtgcg gataaagagt cccagtagca acgcgccggt aagcagggta agcgagatga
     6241 cccacagcga caaattccct ttcagcgcgg ttttagcgct atagaccaac agcaaaatgg
     6301 caataatcag catcaccgca tggccaagat tgagcggttg atcgcgacgg cccgcctgac
     6361 gaggaacata gcgggcggtt aagcccatga cgaccagcac aatcggcacg ttgatcagga
     6421 aaaccgatcc ccagtaaaaa tgctctaata atatgccgcc gatgagcggc ccaaacgccg
     6481 ctccgcccga acctaccgca gcccagacgc ccagcgccat gttgcgatgc ttctcttcac
     6541 aaaaggtggc gcgtatcccg gccagcgtcg ccgatacaat catcgccgcg ccaatagcca
     6601 gtaataccct ggtggcgata agccaactgg cggtatgcga aaacgccgcc gccagtgatg
     6661 ccaggccaaa gagcgtcccg cccagcatca gcaggcgttt aaaaccgata cgatcgccaa
     6721 gcgcgcccat cggcaacacc atgccagcca tgaccaaaga ataaatatca atgatccaca
     6781 gcagctcgtt gccgctggcc cccagtgtca tactcagtgt cggcgcggcg acatgcaaga
     6841 ccgtggcatc aatggcgaca ggaatataga ccagcacaat aatgactaac gttaaccact
     6901 gacgaaacat aactctccct tcaaaaactt aaacctggac acctgtccaa tttcaggatc
     6961 ctacggtaag ttgaacgaat gtccagcttt ttgttacact gcgcgcattg gctaatgtgg
     7021 ggaaaatatg agttacctta accgggatga acgccgcgaa gtgatcctgc aagcggcgat
     7081 gcgcgtggcg ctggcagagg ggtttgccgc catgacggtg cgacggatcg catcagaagc
     7141 cgatgtcgcc gccggccagg tgcatcacca cttcagctcg gcgggcgagc tcaaagcgct
     7201 ggcctttgtc catttgatcc gtaccctgct cgatgccggg caagttccgc cgcccgccac
     7261 ctggcgtgca cggcttcacg ctatgttggg tagcgaagac ggcggctttg agccttacat
     7321 aaaattgtgg cgagaggcgc aaattctggc cgaccgggac ccgcacatca gagatgctta
     7381 tctcctcacg atgcagatgt ggcatgagga aacggtcaca attatcgagc agggcaaaca
     7441 ggcaggagaa tttacgttta ctgctaacgc cacggatatc gcctggcggc ttatcgcact
     7501 ggtgtgcggg ctggacggta tgtatgtgct gggtattccg gaaatggccg atcccgcgtt
     7561 taaataccat ctggatcgta tgattacgct tgaa
//
LOCUS       DAJVBX010000207         7543 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.207, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000207 DAJVBX010000000
VERSION     DAJVBX010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 7543)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7543)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7543
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.207"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(216..2501)
                     /locus_tag="OPV72_003876"
     CDS             complement(216..2501)
                     /locus_tag="OPV72_003876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010989300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916050.1"
                     /translation="MVDRYFELAQAPFDPVRIWQWIGNLNFHHQCQADQSKSVQVLRE
                     NDTLRQGIIAYVFGPLTDRNEIFNTRVEKFDGHLHSHSGLHLWRNDYKFILNLAFEAD
                     NVDLWASFLVNHQRYRNKEEQGPDDLRAQMRRHALSKPAFMREWARYNNAMKLSGQKS
                     QLRRFRHSRKMKRRDRKQREIHARNIKFVNENRDIVERGRHWRCLLRFAELVLMHPER
                     IELEFGDEKLVRTALRNCLDFITPEVPTLPELAALQCESKYRHSETVLYAACLEILRA
                     EGNLECVNIELLTALRTNIHRGYHSVSKEERDALQTEIDRLIFPYSESAEKYLRQYVE
                     PQLTQPCPHPEIGVLSRQEVFRHSRAKLSIEWLRRFPDVSLNSVDTLFEIAAQYGDRE
                     NLKEIIAERCSEMMSGWPNPKENEDIERKRIFWLVREFYFMENIADTYWAWLKSDKNN
                     LLHFYERSGRMNRSEHRAWPELASIKVEAILDAFIEHWPRVDLPDSWGSDSPKEEKAY
                     RFLTDLIWSINSDTSDDAIPVLDRLLNDPRFTNLHKELQSIYADQIRKKALRDFEPPT
                     PDEIVQRLDCDSVVTVEGLRQLVLQELHDFQKAIDGGEFNSADRFYEKNERLDEVKST
                     EIIAERLSLRLQPQGIAITPEHQLKGQNRSDFTASKLIGGRRRLLVTEVKGQWHRELY
                     SAASAQLYDRYSIHPDAEQQGIFLVIWFGESETVAGRKTHGIKTAQELKISIEAVLPA
                     DLRDLIDVFVLDVSRNGGHQR"
     gene            complement(2582..4255)
                     /locus_tag="OPV72_003877"
     CDS             complement(2582..4255)
                     /locus_tag="OPV72_003877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010989301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916051.1"
                     /translation="MNSIFYLERHFTHGDRTYTETELLAASTHVVVLAEPGGGKTELM
                     KSLARKLNTTVLNASVFAYAGADKENSALVIDAVDEVARIDQSGIHKLLALARTSKPT
                     RVIMSSRSSEWGQACTSIFEKFLGFSPMVVRLKEFDQDEQHAIFKHHAPEEDFFAFQT
                     EVTRFSLDMLLPNPQFLKMFTDAYLESGRRFADKRSIFALAVERLAKEVNPDIPKAPV
                     SLSVAQKISFSAEVYAKLLLSGAEGVSTIDVTANRMYPMLPALFSSSAACYDILSTQL
                     FKPGDKEDQHRPVHKIVAEYCAADYLIKRIADPVDVLTLPKCLPVIAPNGIARDELRG
                     LLGWMAALGNRSVQGSIIELDAYAVLANGDPSQLERSSKRQLLYQLKEIEAADPYFRR
                     SDFWRRFSAAGFFTQDVVEEIKPLLTMGNDGHLRDLILELLADSPVNSQLVPELSQLT
                     LNPNESEHIRTLASRCLLNIKEYDCIGALAVLIFEASNISLNIAANVIEVTGPEKFDH
                     RYLSGFFRVCANLYPGHEEQFERVVGLVILLKSSFPVFHCILSNFFWTN"
     gene            4802..5263
                     /locus_tag="OPV72_003878"
     CDS             4802..5263
                     /locus_tag="OPV72_003878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000246267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916052.1"
                     /translation="MATTLTQTHPLLSVPFNAATDFTVLAEHCKQFAEILIEHDDPTL
                     KMALCGRLNACLQLLQPSLLDPIPEHMMDSLIVDTLPTRSPRFDPECTELCNYCLALT
                     QVLTGQGLLPETRNYLGCLLYDLIHYFSDEITAPRWLRTADGVKFIDEVTA"
     gene            5260..5481
                     /locus_tag="OPV72_003879"
     CDS             5260..5481
                     /locus_tag="OPV72_003879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000193311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR9916053.1"
                     /translation="MTQQDWHPADIIAGLRKRGTSLAALSRQSGLASSTLANALIRHW
                     PKGERLIAEALGIAPEQIWPSHYRKPENY"
     gene            complement(5874..6068)
                     /locus_tag="OPV72_003880"
     CDS             complement(5874..6068)
                     /locus_tag="OPV72_003880"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916054.1"
                     /translation="MSESSHELAQLSCLVQVEKAACVTFPLYAVKVTHWTGAVSENLS
                     LVQFYDHAAAKPAVFAGRSP"
     gene            6338..7120
                     /locus_tag="OPV72_003881"
     CDS             6338..7120
                     /locus_tag="OPV72_003881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000511749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase domain-containing protein"
                     /protein_id="HCR9916055.1"
                     /translation="MGILAQEMKRLAQQAGGSHKTVHDRIKLAQGITKRSLQNEMAAV
                     RCILKQAGRDRLAQSERLNNRSLGLSGASRNGTKLAITPEHYRDVLETARVKDPGMAA
                     ALELSKLMGLRSQEAVQSVQSLKTWRQALDRGDTRLTVVFGTKGGRPRETIILDAVAV
                     RKALDNALAVAEDRHDRLIDKPDLKTAMKYWHSQASRLGLTGAYSPHSLRYAWAQDAI
                     RHYLAQGFSEKEALAMTAMDLGHGDGRGRYVAQVYGRKDGGD"
BASE COUNT         1902 a         1824 c         1847 g         1970 t
ORIGIN      
        1 atatacagtt atgagatcaa gccaaataat ttgatatata tcaaatcatg gttatattat
       61 gtttaaaaca taagagctac aaagcaaaca aaataaagga atccagtttt ccagatggcc
      121 aatggtattc acttggtggc atggtaatac ttacggtgtt ttgttggctc tcgctaatta
      181 acccgatctc tggttaatta gcgagagcta tattgctaac gttggtggcc accgttccgt
      241 gaaacatcta aaacgaaaac atcaattaaa tcacggagat cagccggtag tactgcttca
      301 atactaattt ttagctcctg agcggtttta attccgtggg ttttgcggcc agcaacggtt
      361 tcgctttctc caaaccatat gacaagaaag ataccttgct gttcggcatc agggtgaatg
      421 gaataacggt catagagttg ggctgaagca gcagaatata actctctgtg ccactggcct
      481 ttgacttccg taaccagcag ccgtcttctt cctccaatca atttagatgc tgtgaaatca
      541 ctcctgtttt gccctttcaa ctgatgctct ggagttatag cgataccctg aggctgaagt
      601 cttaaactca ggcgctccgc aataatctct gtggacttta cctcatcgag gcgttcattt
      661 ttctcataga agcgatcagc cgagttaaat tccccgccat caatcgcttt ctgaaaatca
      721 tgaagctcct gaagaactaa ctgacgcagg ccttcaacgg taacgactga atcacaatca
      781 aggcgttgaa ctatctcatc tggcgtcggt ggttcaaaat ctctgagtgc tttttttctg
      841 atctgatcag cgtatatgct ttgcaactct ttatgtagat tggtgaaacg tggatcgtta
      901 agaagacggt ccagcactgg tattgcatca tcggaagtgt ccgagtttat tgaccaaatc
      961 aaatcagtca aaaagcggta ggctttctct tctttagggc tatcactacc ccagctatca
     1021 ggtagatcaa ctcgcggcca gtgttcaatg aaagcgtcta aaatggcttc aactttaatt
     1081 gaggcgagtt ccggccaggc acggtgctcg cttcgattca tacgtccaga acgttcataa
     1141 aaatgcagta aattattttt atcagatttt aaccatgccc aataagtatc cgcaatgttc
     1201 tccataaagt agaattcacg taccagccag aatattcgtt tgcgttcaat atcctcattt
     1261 tctttcggat tgggccagcc tgacatcatc tctgagcaac gctctgcaat aatctctttt
     1321 aaattctcac gatcgccgta ttgagcggca atttcaaaaa gtgtatcgac tgaattaagg
     1381 gatacatcgg gaaaacgacg aagccattca atggaaagtt tagcgcgtga atgacgaaag
     1441 acctcttgtc tacttaatac cccgatttca gggtgagggc atggctgagt gagttggggt
     1501 tcaacgtact gtcggagata tttttcagca ctttcactat aaggaaaaat gaggcggtcg
     1561 atttcagtct gtagcgcatc acgttcttct ttcgaaactg agtggtatcc cctgtgaatg
     1621 ttcgttctta aggctgtaag caactcgata ttgacgcatt caagattgcc ttctgcacgt
     1681 agaatctcca gacaggcggc atataaaacc gtctcagaat gcctgtattt agattcgcat
     1741 tgcagtgctg ctagttcggg tagagtggga acctcgggag taataaaatc cagacaattt
     1801 cgcaacgctg tccgaaccag tttctcgtca ccaaattcta attcaattct ttccggatgc
     1861 atgagcacaa gttctgcaaa acgcagcagg caccgccagt gacgacctcg ctctacaata
     1921 tctctgttct cattaacaaa ttttatgttt ctggcgtgga tctctcgttg ctttctgtca
     1981 cggcgtttca tttttcggct atgtctgaat ctccggagtt ggcttttctg cccggataat
     2041 ttcattgcat tgttgtatcg ggcccattca cgcataaatg cgggcttgga gagggcatgc
     2101 cgacgcattt gtgcccgcaa atcatcaggg ccttgctctt ccttgtttct gtaacgttgg
     2161 tggttgacaa ggaaactcgc ccacaggtca acgttatctg cttcaaaagc cagattgagg
     2221 ataaatttat agtcattcct ccataaatga aggcctgaat gtgagtgcag atgcccgtcg
     2281 aacttttcta ctcttgtgtt gaatatttca ttacgatccg ttaaaggccc aaatacatag
     2341 gcaatgatcc cctgacgaag tgtgtcattt tcccgaagca cttgtaccga tttgctttga
     2401 tcggcctgac attggtgatg aaaattgaga ttacctatcc attgccagat cctcacagga
     2461 tcaaatggtg cttgagccag ttcaaaatag cgatcgacca ttgaaccgac aatcttgctt
     2521 attccattac gacaatcaca ttcataggat tctttcccac aatggcaata aaggttacag
     2581 gttaattcgt ccagaagaag ttcgagagta tgcagtgaaa aacaggaaat gagcttttta
     2641 ataaaataac gaggccgacc actctttcga attgttcttc gtgaccggga tagagattcg
     2701 cacagacgcg gaagaatcca gagagatatc ggtggtcgaa tttttcgggc cctgtgactt
     2761 cgatgacgtt ggctgcaata ttgagtgaaa tattactggc ctcaaaaatc aaaacagcta
     2821 aagcgccaat gcaatcgtat tctttgatat tgagtaagca tctgcttgct agggttcgaa
     2881 tatgttcaga ctcattggga tttaacgtaa gctggctcaa ttcaggcacc aactgactgt
     2941 ttactggaga gtctgccaga agttctaaaa ttaaatcacg taaatgacca tcattgccca
     3001 tcgttaaaag aggctttatt tcctcaacaa cgtcttgcgt gaaaaaacca gccgcgctga
     3061 accggcgcca gaaatcactc cgacgaaagt aaggatctgc ggcttcaatc tctttgagtt
     3121 gatagagaag ctgtcgtttt gatgagcgtt caagctgcga tggatcgccg tttgcgagta
     3181 ccgcataggc gtcaagctca ataatggatc cctgtaccga cctgttgcct aatgctgcca
     3241 tccatccgag cagacctctc aactcatctc tggcaatacc gttcggtgca ataacaggca
     3301 agcactttgg taaagtgagg acatccacag gatcggctat tcgtttaatg agataatccg
     3361 ctgcgcagta ttcagcgaca atcttgtgga ccgggcggtg ctggtcttcc ttatcgccgg
     3421 gcttgaaaag ctgagttgac aatatgtcgt aacaggccgc actgctgcta aacaacgctg
     3481 gcagcatggg atacatccgg tttgccgtca cgtcgatggt gctgactccc tctgcgcccg
     3541 acaacagaag tttggcataa acctcggcag aaaatgaaat cttctgtgca actgaaagag
     3601 atacaggggc tttcgggata tctggattga cttccttagc cagtcgttcg actgctaaag
     3661 caaagattga acgtttgtca gcaaatcgcc tgccactttc taaataggca tcggtgaaca
     3721 ttttcagaaa ctgagggttt ggtaacaaca tgtctaaact aaaccgtgtt acttcggtct
     3781 ggaatgcaaa gaagtcttct tctggcgcat ggtgcttaaa gatagcgtgt tgctcgtctt
     3841 gatcgaattc tttcagcctc acaaccatcg gggagaaacc aagaaatttt tcaaaaatgc
     3901 tggtacaagc ctgtccccat tcgcttgatc tacttgacat gattacgcga gtcggctttg
     3961 atgttctggc gagagcaagg agtttatgaa tacctgattg atcaattctg gcgacttcat
     4021 caacggcatc aattaccagt gcgctatttt ctttatctgc tcctgcgtaa gcaaatacgc
     4081 tggcatttaa gacagtagtg ttcagtttcc gagcgaggct tttcatcagt tccgttttcc
     4141 cgccgccggg ttctgctaac acaacaacgt gcgttgatgc cgccagcaac tctgtctctg
     4201 tgtaggttct gtcaccgtgc gtaaaatgac gttcaagata gaagattgaa ttcatcgtta
     4261 caaaattttt cgtattgaat agcccaaata ttccagcaga aaggaaagct gcgcctgagt
     4321 tttcttgctt atatcagaga tagtacggca tttattcttt gttggtggga tgttttatca
     4381 actgttgtac acattataca acttattgac attaatcaca tttcgccaca gcgatgtgcg
     4441 ggctaacaga taataaacct ttcctgttat ggcggtcttg tctgtggaat ttttattttc
     4501 tgcgatctgc ttccagaacc cctcacttgc tgctattggc taattgcggt atcttttaca
     4561 cgcacctgca aattcaggtg ccgggattag cctcctgatt gacttcatcg acgacacaaa
     4621 ggcgcgtctg cgcttttttt gtgtcgtgcg ttctgctaca tctcaatggt gggccgggcg
     4681 ggggcgctgc aaagcgcgcc ggtgtcgatg aggccggtaa ggctaacccc gtccggttcc
     4741 accaccatga gattagcctc tccggtggtg gtgataaaca ctgctcatcg gaggatgcct
     4801 tatggctacg accctcaccc agacacaccc gctactctcc gttcccttca atgccgccac
     4861 ggatttcacc gtactggcag aacactgcaa acagttcgcc gaaatcctga tcgaacacga
     4921 cgatcccacg ctgaaaatgg cactttgcgg caggcttaat gcctgtctgc aacttcttca
     4981 gccctcactg cttgatccga tcccggagca catgatggac agcctgatcg ttgatacgct
     5041 ccccacccgc tcaccgcgtt tcgatcccga atgtactgaa ctttgtaact actgccttgc
     5101 cctgacgcag gtgctgacgg gacaggggct attaccggaa accagaaatt accttggctg
     5161 cctgctgtac gacctgatcc attatttttc tgatgaaatc acggccccgc gctggctgcg
     5221 taccgctgac ggcgtgaagt ttattgacga ggtgacagca tgacgcaaca ggactggcat
     5281 cccgccgaca ttatcgcggg gttgagaaaa cggggcacct cgctggcggc gctgtcccgt
     5341 cagtcggggc tggcgtcctc aacgctggca aatgcgctga taaggcactg gcccaaaggc
     5401 gaaaggctga ttgccgaagc gttgggtatt gcgccagagc aaatctggcc ttcccactac
     5461 cgcaagcctg aaaattacta aatcgtctct cccgatcttc tgatggcttt gctgtcagaa
     5521 gatcgggaga aggcaagcga agcgcggcag ttcaggctcg caaataatct ttttgacgta
     5581 caaacagttt ttcctttctg cgccagcggc actggcgtag tctccctcct gctccatgct
     5641 gtcgtcgaca gcgcccaacg cttcacaacc tgaaagaagc gcctgttatc aggacggttg
     5701 atccgtttac cggtgcagac ctctgcaaac accgggtcgc agaacatcgc gacggaggcc
     5761 cgagttttaa cactatatgt cctttactgc gccagcctgc tggtctgaat ctgctccgcg
     5821 ccgaaatttt cccggctaac ctgtatctgc tgacaccctc tgcgcctttt accttacgga
     5881 ctgcggcctg caaagacagc aggctttgct gctgcgtggt cgtaaaactg caccaacgat
     5941 aaattttcag acactgcacc agtccagtgc gtcactttaa ccgcgtaaag cgggaaagtg
     6001 acgcacgcag ccttttcgac ctgcaccaga caactcaact gcgccagctc atggctggat
     6061 tctgacactg ccttttcagg ccattttacc cataaggaga acatgagccg ataccgaggc
     6121 ggatccggac gatccggggg ataacccgca caagcgggcg gctgctctga gagcacaacc
     6181 gaagccccac cacacctcaa cggctgccgc cccggcgctc aggtatcgtt cgcagccccg
     6241 acaaaaaaac aggggctatc ggcctgtgcg ccggggaaag cggtatcagt gttggttttt
     6301 tgggatgagt ttgcggcaat catgaaaggg ggaaaatatg gggattctgg cgcaggaaat
     6361 gaagcggctt gcacaacagg cgggcggcag ccataagacc gttcacgatc gcattaagct
     6421 ggcgcagggc atcacgaagc gttccctgca aaacgagatg gcggcggtac gttgcattct
     6481 gaaacaggcc gggcgtgaca ggctggcgca gagtgagcgg ctgaacaacc gttctcttgg
     6541 tctgtctggc gcatcccgca acggtacaaa gctggctatc acgccggagc actatcgtga
     6601 cgtgctggag acagcccgtg taaaagatcc ggggatggcg gcagcgctgg aactctcaaa
     6661 gctgatggga ttacgctcgc aggaggcggt gcagagcgta cagtcgctga aaacgtggcg
     6721 gcaggcgctg gatcgtggtg acacccgctt aaccgtagtg tttggcacca aaggcgggcg
     6781 accccgcgag acgattattc ttgatgcggt agcagtcaga aaagcgctgg ataatgcgct
     6841 ggctgtggca gaagatcgtc acgacaggct gatagataag ccggatctga aaaccgcgat
     6901 gaaatactgg cacagtcagg cgtcacgtct cggcttaacg ggcgcatatt ccccgcactc
     6961 gttgcgctat gcgtgggcgc aggatgcgat ccgtcattat ctggcgcagg gatttagtga
     7021 gaaggaagcg ctggcaatga cggcgatgga tttggggcac ggcgacggac gcggacggta
     7081 tgtggcgcag gtttacggga gaaaggatgg tggtgattga tagcttcaga cttgcaatat
     7141 gaggttatcc atcggttttc gtacaaaaaa ttttgggggc aaaatttttt gtacggtttc
     7201 cttttaataa cgatgtttct aaatggtcta gcctattaac aggcttctgg tgcagcattc
     7261 cgttattttt ttctggtgat tgtgccagca aaagggaaaa ggccagataa aggtaaaggg
     7321 cggctaaggg taacagcgcc agaccggaaa aggccaaagg gcttaaaagg ataaagctgg
     7381 cgcagatcgg tatttatccg gtggtatctg gcgcaatcct gacatagaca ggcgacggca
     7441 gactggtgca gataaacgat gacactgaac tggtgcagtt atggcgtatc ggcaaatcag
     7501 tttctggtgc agattgtctg gctgctatcg cctgaaatta ttc
//
LOCUS       DAJVBX010000208         7324 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.208, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000208 DAJVBX010000000
VERSION     DAJVBX010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 7324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7324
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.208"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..105
                     /locus_tag="OPV72_003882"
     CDS             <1..105
                     /locus_tag="OPV72_003882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461238.1"
                     /note="catalyzes the of heptose(II) of the outer membrane
                     lipopolysaccharide core; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HCR9916056.1"
                     /translation="KNKRGVKFDPDYLNALVMYAENGKLFLDGEFVPG"
     gene            complement(150..575)
                     /gene="nudI"
                     /locus_tag="OPV72_003883"
     CDS             complement(150..575)
                     /gene="nudI"
                     /locus_tag="OPV72_003883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphatase NudI"
                     /protein_id="HCR9916057.1"
                     /translation="MRQRTIVCPLIQNDGCYLLCKMADNRGVFPGQWALSGGGVEPGE
                     RIEEALRREIREELGEQLILSDITPWTFRDDIRVKTYADGRQEEIYMIYLIFDCVSAN
                     RDICINDEFQDYAWVKPEELALYDLNVATRHTLALKGLL"
     gene            854..1396
                     /locus_tag="OPV72_003884"
     CDS             854..1396
                     /locus_tag="OPV72_003884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311165.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916058.1"
                     /translation="MKKSILLGFAGMLFVSASAQAISISGQAGEDYTNIGVGFGTEST
                     GLALSGNWMHNDDDGDAAGVGLGLNIPVGPLLATVGGKGIYTNPKDSDEGYAAAVGGG
                     LQWKIGNSFRLFGEYYYSPDSLSSGIESYEEANAGARFTIMRPLSIEAGYRYLNLAGK
                     DGNRDNAIADGPYVGVNASF"
     gene            1511..2707
                     /locus_tag="OPV72_003885"
     CDS             1511..2707
                     /locus_tag="OPV72_003885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide deamidase-related
                     protein YfaY"
                     /protein_id="HCR9916059.1"
                     /translation="MLNVEMLSTGDEVLHGQIVDTNAAWLADFFFHQGVPLSRRNTVG
                     DNLDSLVAILRERSQHADVLIVNGGLGPTSDDLSALAAATAKGEGLVLHQAWLTEMER
                     YFQQRGRVMAPSNRKQAELPASAEFINNPVGTACGFALQLNRCLMFFTPGVPSEFKVM
                     VEKEILPRLRARFSLPEPPLCLRLTTFGRSESDLAQRLDSLPLPPGVTMGYRSSMPII
                     ELKLTGPATQREAMLALWPEVKRVAGQNLIFEGTENLPAQIARRLQERQLSLTLSEQY
                     TSGLLALQLSRAGAPVLASEVVPSQEETLAQTAHWTTERRSNHYAGLALAVSGLENEH
                     LNFALATPDGTYALRVRFSANRYSLAIRQEVCAMMALNMLRRWLNGEDITSEHGWIDV
                     VESLTS"
     gene            2957..3739
                     /locus_tag="OPV72_003886"
     CDS             2957..3739
                     /locus_tag="OPV72_003886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HCR9916060.1"
                     /translation="MLESSKVPALTRAIDILNLIARIGPCSAAIIIETLRIPKSTAYL
                     LLNELKRQRFISLDHQENYCLWTKLVELSGHALSKMDLRELARPRLTQLMDEIGLLCH
                     LGIIDHENAYYILKVESSSTISVRSHEGKSLSLYRSGIGKCLLAWQPAAVRKAIIEKM
                     VWERATLTTITEPQQLNDELERIRQRGWSFDNGEDYPDVRCVAAPVFNARNELTAAIS
                     LVGTRLQINEENLDYLAGKAIACAKDISRLLGWKSPFDSLAS"
     gene            3753..4958
                     /gene="rhmD"
                     /locus_tag="OPV72_003887"
     CDS             3753..4958
                     /gene="rhmD"
                     /locus_tag="OPV72_003887"
                     /EC_number="4.2.1.90"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416750.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnonate dehydratase"
                     /protein_id="HCR9916061.1"
                     /translation="MTLPKIKHVRAWFIGGATAEKGAGGGDYHDQGGNHWIDDHIATP
                     MSKYRDYEQSRQSFGINVLGTLIVEVEAENGQTGFAVSTAGEMGCFIVEKHLNRFIEG
                     KCVSDIKLIHDQMLGATMYYSGSGGLVMNTISCVDLALWDLFGKVVGLPVYKLLGGAV
                     RDEIQFYATGARPDLAKEMGFIGGKMPTHWGPHDGDAGIRKDAAMVADMREKCGPDFW
                     LMLDCWMSQDVNYATKLAHACAPFNLKWIEECLPPQQYEGYRELKRNAPAGMMVTSGE
                     HHGTLQSFRTLAETGIDIMQPDVGWCGGLTTLVEIAALAKSRGQLVVPHGSSVYSHHA
                     VITFTNTPFSEFLMTSPDCSTLRPQFDPILLDEPVPVNGRIHKSVLDKPGFGVELNRD
                     CHLKRPYSH"
     gene            5014..6303
                     /locus_tag="OPV72_003888"
     CDS             5014..6303
                     /locus_tag="OPV72_003888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR9916062.1"
                     /translation="MSITLLDGVVKKNRARLIPFMLALYVLAFLDRSNIGFAKETYQI
                     DTGLSNEAYALGAGIFFVVYAFLGVPANLLMRKFGARTWIGTTTLLWGFLSAAMAWAD
                     SEAKFLIIRTLLGAAEAGFFPGMIYLTSQWFPQRNRASIMGLFYMGAPLALTLGSPLS
                     GALLEMHGFMGHPGWFWMFVIEGLLAIGAGIFTFFWLDDTPQQARFLSLEEKNALIRQ
                     LASEEEKKVTSRLADALRNGRVWQLAIIYLTIQVAVYGLIFFLPTQVAALLGTKVGFT
                     ASVVTAVPWVAALLGTWLIPRYSDRTGDRRNVAAVTLLAAGIGIGLSGLVSPVLAILA
                     LCVAAVGFIAVQPVFWTMPTQLLSGTALAAGIGFVNLFGAVGGFIAPILRVKAETLFA
                     SDAAGLLTLAGVAIIGSLIIFTLSVNRPVAQSGAAHH"
     gene            6329..7132
                     /gene="yfaU"
                     /locus_tag="OPV72_003889"
     CDS             6329..7132
                     /gene="yfaU"
                     /locus_tag="OPV72_003889"
                     /EC_number="4.1.2.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxy-L-rhamnonate aldolase"
                     /protein_id="HCR9916063.1"
                     /translation="MNALLSNPFKEGLRKRDTQIGLWLSSTTSYMAEIAATSGYDWLL
                     IDGEHAPNTVQDLYHQLQAIAPYASQPVIRPIEGSKALIKQVLDIGAQTLLIPMVDTA
                     EQARQVVSATRYPPLGQRGVGASVARAARWGRIDNYMAQANESLCLLVQVESKVALEN
                     LDAILEVEGIDGVFIGPADLSASLGYPDNAGHPEVQRIIESCIYRIRAAGKAAGFLAV
                     DPAMAQKCLAWGANFVAVGVDTMLYTEALDSRLAMFKSVQSVSTAKRSY"
     gene            7138..7314
                     /locus_tag="OPV72_003890"
     CDS             7138..7314
                     /locus_tag="OPV72_003890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-binding protein"
                     /protein_id="HCR9916064.1"
                     /translation="MPDGTYALRVRFSANRYSLAIRQEVCAMMALNMLRRWLNGEDIT
                     SEHGWIDVVESLTA"
BASE COUNT         1642 a         1777 c         2066 g         1839 t
ORIGIN      
        1 aaaaataagc gcggcgtgaa gtttgatccg gactatctta atgcgctcgt tatgtatgcg
       61 gaaaacggaa aactcttttt agacggtgaa tttgttcccg gctagccgca tgttaaaagc
      121 gtaaagacag cctgaagcgg ctgtcgttat tataataacc ctttcaatgc taatgtgtgg
      181 cgtgtcgcta cattcaaatc atacagcgcc agttcttctg gcttgaccca ggcgtagtcc
      241 tgaaattcgt cgttaataca tatatcgcgg ttagcggaaa cacagtcgaa gatgagataa
      301 atcatataaa tctcttcttg tctgccatca gcgtacgttt taacgcggat atcgtcgcga
      361 aaggtccacg gcgtaatatc gctcagaatc agttgttcgc cgagttcctc ccgaatctcc
      421 cgacgcagcg cctcttcaat acgttcgcct ggctcgaccc cgccgcccga cagcgcccac
      481 tgaccgggaa agacgccgcg gttgtcggcc attttgcaca gcagataaca gccatcattt
      541 tgaattaatg ggcaaactat agttcgttga cgcataagtc gcttccttaa accaccaggc
      601 catcagctta acaaatcatt ctgcgaaatt ctttgtgaaa aatggaagcg ataacgcaga
      661 ctgcgttttt tgttaatttt gttgatgcag gcgtcgccat gtgatggcgc aatgatgcgt
      721 cacggcgaaa gtagtatttc gttacaatat gtttttggaa tggtttctta gtgcattgat
      781 tcctcagcgt ctggcagtac aattctgccg ttttggggag tttttcttta tgtgcttgct
      841 ggaaagggta aaaatgaaaa aaagcatatt attaggtttt gccggaatgc tgttcgtttc
      901 tgcatcggcg caggccatca gtattagcgg ccaggcgggc gaagattaca ccaacattgg
      961 cgtgggtttt ggtacggaat cgacgggact ggcgctaagc ggcaactgga tgcacaacga
     1021 tgatgatggc gacgctgcgg gcgtgggtct ggggctgaac attccggtgg gaccgctgct
     1081 ggcgacggta ggcggtaaag gtatttatac caatccgaaa gacagcgatg aaggctatgc
     1141 ggcggctgtc ggcggtgggt tacaatggaa aatcggcaac agcttccgtc tgttcggcga
     1201 gtattattat tcaccagatt cgctgtccag cggtatcgaa agttatgaag aagcgaatgc
     1261 aggcgcgcgt ttcaccatta tgcgcccgct gagcattgaa gccggttatc gttacctgaa
     1321 cctggcgggt aaagacggca accgcgacaa tgcgattgct gacggccctt atgttggcgt
     1381 aaacgccagt ttttgatgct aacggcgcgg caatcgtcgc gccatattcc tccttttccc
     1441 gtcattcttc tttccacgtc atattcgtct ttgcgttata gtgttttcat cataaaagca
     1501 ggagaacaca atgctaaatg tggaaatgct atccaccggg gatgaggtgt tgcacggaca
     1561 aatcgttgac accaatgccg cctggctggc tgattttttc tttcatcagg gcgttccgtt
     1621 atcacggcga aatacggtag gcgataatct ggacagtctg gtcgctatct tgcgtgaacg
     1681 cagtcaacat gctgatgttt tgattgttaa tggcgggtta gggccgacca gcgatgattt
     1741 aagcgcgctc gccgcggcaa cggcaaaagg cgaaggatta gtactgcacc aggcgtggct
     1801 gaccgaaatg gaacgttact ttcagcagcg tggtcgcgtg atggcgccga gcaaccgtaa
     1861 acaggcggaa ctgcctgcca gcgcggagtt tattaataat ccggtcggca ctgcctgtgg
     1921 atttgcgcta cagctcaacc gctgcctgat gtttttcacc cccggcgtac cgtcggaatt
     1981 taaggttatg gtggagaagg aaatcttacc gcggttacgc gcgcgttttt cgctgccgga
     2041 gccgccgctt tgcctgcggt taacgacttt tggacgttca gaaagtgacc tcgcgcagcg
     2101 tctcgattca ctgccgttgc cgcccggcgt gacgatgggg tatcgctcat caatgccgat
     2161 cattgaactg aaattgaccg gcccggcgac gcaacgggag gcgatgctgg cgttatggcc
     2221 agaggtcaaa cgggtcgccg gacagaacct gatttttgaa ggtacggaaa atctgccggc
     2281 gcaaatagcc cgccgcctgc aggaaaggca gttgagtctg acgttgagcg agcaatacac
     2341 cagcggttta ctggcgctac agctttcccg tgccggggcg ccggttcttg ccagcgaagt
     2401 cgttccttct caggaagaga cgctggcgca aacggcacac tggacgacag aacggcgcag
     2461 caatcattat gccggtctgg cgctggccgt gtcggggctg gaaaacgaac atcttaattt
     2521 cgcgctggcg acgccggatg gcacgtatgc cttacgcgtg cgttttagcg ccaatcggta
     2581 tagtctggca atacgtcagg aggtctgcgc gatgatggcg ctaaatatgc tgcgccgttg
     2641 gcttaatggc gaggacatta ccagcgagca tggctggata gacgtggttg aatcattgac
     2701 atcataatcc ctttctctta tctgcgatgg gaacgacatc gtgagccgga taaggccgct
     2761 atgccattat ccggcaatat tatctgcttt tttgtccagc caattgtact gaatacaaag
     2821 taatacgtgc gttaattcac atttatatgg ttaacccttc cactccgttg gaaggcggat
     2881 aagctttgac gcgcttcaca attttttccc tactgacctt tcacactgat tccagtgtct
     2941 cagactggag tccaatatgt tggaatcaag taaagtcccg gctcttactc gcgcaatcga
     3001 catcctcaat ttgatcgcgc gtattggccc atgcagcgcg gcaatcatta ttgaaacgtt
     3061 gcgtattcca aaaagcaccg cgtacctgct gttgaatgaa ttaaaacgtc agcgatttat
     3121 tagcctcgat catcaggaga actactgcct gtggactaag ctcgttgaat tgtcgggtca
     3181 tgcgctcagc aagatggatc tgagggagct ggcgcgtcct cgtctaacac aactgatgga
     3241 tgaaatcggg ctgctgtgtc acttggggat catcgaccac gaaaatgcgt attacatact
     3301 gaaagtggaa tcctcatcca ctatcagcgt gcgctcgcat gaggggaaaa gcctctctct
     3361 ttatcgttcc ggcatcggca aatgcctgct ggcatggcag ccggccgccg tacgcaaagc
     3421 cattattgaa aaaatggtat gggagcgagc cacgctgacc accatcaccg agccgcaaca
     3481 attgaatgat gagctggaac gcattcgcca gcgtggatgg agctttgata acggggagga
     3541 ttatccggat gtccgctgcg ttgccgcacc ggtatttaat gccagaaacg aactgaccgc
     3601 ggcaatttca ctggtcggca cgcgcctgca aatcaacgaa gagaatcttg attatttggc
     3661 cggtaaagct attgcctgtg ccaaagatat ttcacgcctg ttgggatgga aaagtccctt
     3721 cgactcactc gcatcttaaa atggagaata ttatgactct tcctaaaatt aaacacgttc
     3781 gagcctggtt tattgggggc gctaccgcag agaaaggggc tggcggcggg gattatcacg
     3841 accagggagg aaatcactgg attgatgacc atatcgccac tcccatgagc aaatatcgcg
     3901 actatgagca gtctcgtcag tcttttggga tcaacgtgtt agggacgctg attgtcgaag
     3961 tagaggcgga aaatgggcag acggggttcg ccgtttcgac agcaggggag atgggctgtt
     4021 ttatcgtaga aaaacatctt aaccggttta ttgaaggcaa atgcgtaagc gatatcaaac
     4081 ttattcacga tcagatgctc ggcgcgacca tgtactactc cggttccggc ggtctggtga
     4141 tgaacacgat ttcctgtgtg gatctggcgc tgtgggatct gtttggcaag gtggttgggc
     4201 tgccggttta taaattgctg ggcggagcgg tacgcgatga aattcagttt tacgccaccg
     4261 gcgcacgccc ggatctggct aaagaaatgg gctttatcgg cggtaaaatg ccgactcact
     4321 ggggaccgca cgatggtgat gcggggatcc gtaaagatgc cgcgatggtg gcggatatgc
     4381 gtgaaaagtg cgggccggat ttctggctga tgctcgactg ctggatgagt caggatgtga
     4441 actatgcgac taaactggct cacgcctgtg cgccatttaa tctcaaatgg attgaagagt
     4501 gtctgccgcc gcagcagtat gaaggctatc gcgaattaaa acgcaacgcg cctgcaggga
     4561 tgatggttac cagcggcgaa caccatggta cgctgcaatc cttccgcact ctggcagaaa
     4621 ccggcattga tattatgcag ccggatgttg gctggtgcgg cggattaacc acgctggttg
     4681 agatcgccgc gcttgccaaa tcgcgcgggc aactggtggt gccgcacggt tcgtctgtct
     4741 attcgcacca tgcagttatt actttcacta ataccccttt cagcgagttc ctgatgacca
     4801 gcccggactg ctccaccctg cgtccgcaat ttgacccgat tctcctggat gagccggtgc
     4861 cggtgaatgg acgcatccat aaatcagtgc tggataagcc gggcttcggc gtcgagctta
     4921 accgtgactg tcacttgaaa cgcccttata gccactaata actcgtgcgt tgcctttgta
     4981 cggcaacgcc ctcatcctgt tgaggatatt gctatgagca tcactttact tgacggcgta
     5041 gtgaagaaaa accgcgcacg tttaattcct tttatgttgg cgctgtacgt actggcgttt
     5101 ctggatcgtt caaatattgg ttttgccaaa gagacctatc agatagatac cgggctaagt
     5161 aatgaagcct acgcgctagg ggccggtatt ttctttgtgg tttacgcttt ccttggcgta
     5221 ccggctaacc tgctgatgcg caaatttggc gcaagaacct ggatcggcac gactaccctg
     5281 ctgtggggct ttctctctgc tgcgatggcc tgggcggata gtgaagcaaa atttctgata
     5341 atccgcacgc tattgggcgc ggcggaggct ggatttttcc ccggcatgat ctatctaact
     5401 tcacaatggt tcccgcagcg taaccgtgcc agcattatgg ggctatttta tatgggcgcg
     5461 ccgctggcgt taacgttggg ttcgccgctc tccggcgctc tgctggagat gcatggtttt
     5521 atggggcacc cgggatggtt ctggatgttc gttatcgaag gcctactggc gattggcgca
     5581 gggatattca cctttttctg gcttgatgac actccgcagc aggcgcgttt tcttagcctg
     5641 gaagaaaaga acgcgcttat caggcaactg gcgagcgaag aagagaaaaa ggtcacgtca
     5701 aggcttgcgg atgcgctgcg taatggacgc gtctggcaac tggctattat ttatctgacg
     5761 attcaggtgg cggtatacgg actcatcttt ttcctgccga cccaggttgc cgcgctattg
     5821 ggcactaaag tgggctttac cgcttcggtg gtaacagcgg ttccctgggt ggcggctttg
     5881 cttggcacat ggcttattcc tcgctactcc gaccgtaccg gcgatcgccg taacgttgcg
     5941 gcagtgacgc tactggctgc gggcattggc attggcctgt caggtctggt ttctccggtg
     6001 ctcgctattc tggcgctctg tgttgcagca gtaggattta ttgccgttca gcccgtattc
     6061 tggaccatgc caacgcagct actttccggt acggctctgg cggcaggaat tggtttcgtt
     6121 aatctgtttg gcgctgtggg cggttttatt gccccaattc tgcgcgtaaa agcggaaacg
     6181 ttgtttgcca gcgatgcggc gggcctgctg acgctggccg gagtcgccat cattggctca
     6241 ttaattatct tcacgctgag cgttaatcgt ccggtggcgc aatccggcgc tgcgcatcat
     6301 taatcttatc tacgttgtaa ggatcgctat gaacgcattg ttatcaaatc cttttaaaga
     6361 aggattacgt aaaagggata cgcaaattgg tttgtggctc agttcaacca cctcttatat
     6421 ggcggagatt gcggcgacgt cgggttatga ctggttgtta atagatggcg agcacgcgcc
     6481 taatacggtg caggacttgt atcatcagtt acaggccatc gccccatacg ccagccagcc
     6541 ggtgattcgc ccgatcgagg gaagtaaagc gctcattaaa caggtactgg acatcggggc
     6601 gcaaacgcta ctgatcccga tggttgacac cgcagaacag gcgcgccagg tcgtttccgc
     6661 tacccgatac ccgccgttgg ggcaacgagg cgttggcgcg agcgtggcgc gtgcggcgcg
     6721 ctgggggaga atcgacaact atatggcaca ggccaatgag tcgctctgcc tgttggtgca
     6781 ggttgaaagc aaagtggcgc tggaaaacct tgacgcgatt ctggaggttg aaggcattga
     6841 tggcgtcttt atcggtccgg cagatctctc tgcttcattg ggttaccccg ataatgccgg
     6901 acacccggaa gtgcagcgaa tcattgaatc gtgtatttat cgtattcgcg ccgccggaaa
     6961 agcggcgggt tttttggcgg tcgatccggc aatggcgcag aaatgtctgg cgtggggcgc
     7021 gaattttgtc gcggtcgggg tagatacgat gctctacacc gaggcgctgg acagcaggtt
     7081 ggcgatgttt aaatctgttc agtcagtaag cacggcaaaa cgtagttatt gagaaaaatg
     7141 ccggatggca cgtatgcctt acgcgtacgt tttagcgcca atcggtatag cctggcaata
     7201 cgtcaggagg tctgcgcgat gatggcgcta aatatgctgc gccgctggct taatggcgag
     7261 gacattacca gcgagcatgg ctggatagac gtggttgaat cattgacggc atagaacttt
     7321 tagt
//
LOCUS       DAJVBX010000209         7321 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.209, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000209 DAJVBX010000000
VERSION     DAJVBX010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 7321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7321
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.209"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            1..634
                     /locus_tag="OPV72_003891"
                     /pseudo
     CDS             1..634
                     /locus_tag="OPV72_003891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459433.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="SEL1-like repeat protein"
     gene            646..909
                     /locus_tag="OPV72_003892"
     CDS             646..909
                     /locus_tag="OPV72_003892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEL1-like repeat protein"
                     /protein_id="HCR9916065.1"
                     /translation="MIKRKWNLLLLLGFSFASVCQAGDDIDALYSRIAQKDVQALNEL
                     KALAKDNNAQALAELGFIYEYGVAVPKDTIQAIKYYEQACHVE"
     gene            961..2115
                     /locus_tag="OPV72_003893"
     CDS             961..2115
                     /locus_tag="OPV72_003893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001150187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HCR9916066.1"
                     /translation="MQDDVLAKELADKTSKADIDTDAQTVTRLIADEIDTAKQAAESD
                     ITQRSRFIETLRQYAGGGSAMAARITRLGYSKADILHLAELWAQERDPELNFIVGSLY
                     DSGFVEVDDKEARSLQWFRKAAELGQADAQNILGYFYLNGKRGIKRDLQKGGQWYELA
                     AAQGNVDALINLGEIYYSGTRVPLDYARAFEFFERAAKMGKSRALNYLAWMYTNGQFV
                     DTDCRKAAELFAQGRTSFADDPHFQVTCEKDRQARAEAVAMREKNLPKLTFNRDRVFG
                     ASQGSGYACELEFVVKTDRVSSIENLRVSLALKNKAGAMSQQVIAFEPFGLNMQNRNL
                     QGYKSDTLRESTLQPIYQPEFCDVDSYSVTAVTGIVNGKEMDILKAGIFI"
     gene            complement(2163..3053)
                     /gene="cyoE"
                     /locus_tag="OPV72_003894"
     CDS             complement(2163..3053)
                     /gene="cyoE"
                     /locus_tag="OPV72_003894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protoheme IX farnesyltransferase"
                     /protein_id="HCR9916067.1"
                     /translation="MMFKQYLQVTKPGIIFGNLISVIGGFLLASKGSIDYPLFIYTLV
                     GVSLVVASGCVFNNYIDRDIDRKMERTKNRVLVKGLISPGVSLVYATLLGIAGFMLLW
                     FGANPLACWLGVMGFVVYVGVYSLYMKRHSVYGTLIGSLSGAAPPVIGYCAVTGDFDS
                     GAAILLAIFSLWQMPHSYAIAIFRFKDYQAANIPVLPVIKGISVAKNHITLYIIAFAV
                     ATLMLTLGGYAGYKYLVVAAAVSVWWLGMALRGYKVEDDKVWARKLFGFSIIAITALS
                     IMMSVDFMVPNSQNLLTYVW"
     gene            complement(3065..3394)
                     /locus_tag="OPV72_003895"
     CDS             complement(3065..3394)
                     /locus_tag="OPV72_003895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit IV"
                     /protein_id="HCR9916068.1"
                     /translation="MSHSTESGGASHGSVKTYMTGFILSVILTVIPFWMVMTGAASPA
                     VILGSILAMAVVQILVHLVCFLHMNTKSDEGWNMTAFIFTVLIIAILVVGSIWIMWNL
                     NYNMMMH"
     gene            complement(3394..4008)
                     /locus_tag="OPV72_003896"
     CDS             complement(3394..4008)
                     /locus_tag="OPV72_003896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit III"
                     /protein_id="HCR9916069.1"
                     /translation="MATDTLTHATAHAHEHGHHDAGQNKIFGFWVYLMSDCILFSILF
                     ATYAVLVNGTAGGPTGKDIFELPFVLVETFLLLFSSITYGMAAIAMHKNNKSQVISWL
                     ALTFLFGAGFIGMEIYEFHHLIVNGMGPDRSGFLSAFFALVGTHGLHVTSGLIWMAVL
                     MVQVARRGLTSTNRTRIMCLSLFWHFLDVIWICVFTVVYLMGAM"
     gene            complement(3998..5989)
                     /gene="cyoB"
                     /locus_tag="OPV72_003897"
     CDS             complement(3998..5989)
                     /gene="cyoB"
                     /locus_tag="OPV72_003897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002444673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit I"
                     /protein_id="HCR9916070.1"
                     /translation="MFGKLSLDAVPFHEPIVMVTIAAIIVGGLAILAAITYFGKWTYL
                     WKEWLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMRSQQALASAGEAGFLPPHHYDQI
                     FTAHGVIMIFFVAMPFVIGLMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNLSL
                     GVGEFAQTGWLAYPPLSGIEYSPSVGVDYWIWALQLSGIGTTLTGINFFVTILKMRAP
                     GMTMFKMPVFTWASLCANVLIIASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYI
                     NLIWAWGHPEVYILILPVFGVFSEIAATFSRKRLFGYTSLVWATVCITVLSFIVWLHH
                     FFTMGAGANVNAFFGITTMIIAIPTGVKIFNWLFTMYQGRIVFHSAMMWTIGFIVTFS
                     VGGMTGVLLAVPGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFGFKLNE
                     TWGKRAFWFWIIGFFVAFMPLYVLGFMGMTRRLSQQIDPQFHTMLMVAAAGAALIALG
                     ILCQLIQIFVSIRDRDQNRDLTGDPWGGRTLEWSTSSPPPFYNFAVVPHVHERDAFWE
                     MKEKGEAYQQPGQYEEIHMPKNSGAGIVIAAFATVFGFAMIWHIWWLAIVGFAGMIIS
                     WIVKSFDEDVDYYVPVPEVEKLENQHFDEITKAGLKNGN"
     gene            complement(6000..6956)
                     /gene="cyoA"
                     /locus_tag="OPV72_003898"
     CDS             complement(6000..6956)
                     /gene="cyoA"
                     /locus_tag="OPV72_003898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit II"
                     /protein_id="HCR9916071.1"
                     /translation="MRLRKYNKSLGWLSLIAGTALLSGCNSALLDPKGQIGLEQRSLI
                     LTAFGLMLIVVIPAILMAVGFAWKYRASNKDAKYSPNWSHSNKVEAVVWTVPILIIIF
                     LAVLTWKTTHALEPSKPLAHDEKPITIEVVSMDWKWFFIYPEQGIATVNEIAFPANTP
                     VYFKVTSNSVMNSFFIPRLGSQIYAMAGMQTRLHLIANEPGTYDGISASYSGPGFSGM
                     KFKAIATKDRAEFDQWVAKAKQSPNTMNDMAAFEKVAMPSEYNKVEYFSSVKPDLFKD
                     VINKFMGHGKSMDMTQPEGEHSSHEGMEGMDMSHAESANSKG"
BASE COUNT         1973 a         1787 c         1896 g         1665 t
ORIGIN      
        1 gcactgatta cgctaaagcg ctggcattat ttacgcaggt tgaaaatgat ggtactaatt
       61 cgcgctcaac gatgccgttg agttggatgt attataacgg tttaggtact gcacctgatt
      121 gtgataaagc ctggtcgtat tacaagaaag catctcgata tgtaggtaag aaagttgagg
      181 aaaaaatatt tttaagtaag tgcgcagcgg atattcagag tcgaaaaaaa acgcggatgc
      241 tttacccaaa gtaaccctaa aaaaagagag tgttttctct cgcgggataa cggctaaacc
      301 gaaagaatgt gcattaattt ttcagattgg cacagataaa atccgtaaca tggcgaattt
      361 gcatattaca cttgaactga aaaatgctga tggaatggca actgaggaaa cgttgatgat
      421 tccgccattc ggtttgaata ctctggggat agatatgcaa aatcatgatg ttgatcctct
      481 cattacccca tacgatctcc cactgtatac gcaagatttt tgtcacggga tcggcgatat
      541 ccattttacg ctgaaatccg ctacggcaac gattaacggt aagaatgtcg atttgctgaa
      601 agctgacagt gtgcactttt tagataaaga ataagggaat gaaaaatgat aaagcggaaa
      661 tggaatcttt tgcttctgct tgggttttct ttcgcatcgg tatgccaggc aggtgatgat
      721 attgacgcgt tatatagccg tattgcgcag aaagatgttc aggcgctaaa tgagctaaaa
      781 gcgttagcca aagataataa tgctcaagcg ctggcggagt tggggtttat ttatgagtac
      841 ggcgttgccg tgccgaaaga tacgatacag gctatcaagt attatgagca ggcttgtcat
      901 gttgaataac cctatggctg ctacaacgct cgttattttt atctgcatgg cctgggggtg
      961 atgcaggatg acgttttggc aaaagagctt gcggataaaa ccagtaaagc agatatcgat
     1021 actgatgcgc agacggtgac gcgcctgata gccgacgaaa tagatacggc aaagcaagcc
     1081 gcggaaagcg atattactca gcgttcccgg tttattgaaa cattacgcca gtatgccggc
     1141 ggcgggagcg cgatggccgc gcgcatcacg cgcctgggtt attcaaaggc ggatatcctg
     1201 caccttgcgg agctgtgggc gcaggagaga gaccctgaac ttaactttat cgttggtagt
     1261 ctctatgact ctggttttgt tgaggtcgac gataaagagg cgcgttcgtt gcaatggttc
     1321 cgcaaggctg ctgaattggg ccaggctgat gcgcagaata tactcggtta cttctacttg
     1381 aatggaaaac gagggattaa gcgcgatctg cagaaggggg ggcagtggta cgagttggcg
     1441 gctgcgcagg gtaatgtcga tgcgctcata aatcttggtg agatctatta ctccgggacg
     1501 cgggttccgc ttgattacgc tcgggcgttt gaattctttg aacgggcggc gaagatgggc
     1561 aagtctcgcg ctttaaacta tcttgcctgg atgtatacca acggtcagtt tgtcgacacg
     1621 gactgccgga aggcagcgga gttgtttgct caggggcgaa caagttttgc agacgatccc
     1681 cattttcagg tgacctgcga aaaagaccga caggcccgtg ctgaggctgt ggcaatgcgt
     1741 gaaaagaatt tgccgaagtt aaccttcaat cgtgatcgtg ttttcggtgc gagtcagggc
     1801 agcggctatg catgcgagct ggagtttgtc gtcaaaacgg atagagtcag cagtatagag
     1861 aatttacgcg tctcactggc gctgaaaaat aaggccgggg cgatgtcaca gcaggttatc
     1921 gcatttgagc cttttgggct aaatatgcag aaccgcaatt tacaagggta taagtctgat
     1981 acgctacgtg aatcgacatt acaacctatc tatcagccgg aattttgcga tgttgatagc
     2041 tatagcgtaa ccgctgtgac ggggattgtt aacggtaaag agatggacat tcttaaggcg
     2101 ggaattttta tttaaacgcg aaaagaaaga tggcgtatca agcgatacgc catctaaagt
     2161 ctttaccaga cgtaagtcag cagattctgc gaattcggca ccataaaatc aacagacatc
     2221 atgatactca gtgcggtaat cgcaatgata gagaagccga acagcttacg cgcccagacc
     2281 ttatcatctt ccactttgta accgcgtagc gccatgccga gccaccaaac gctgaccgcc
     2341 gcggcgacca ccaggtattt gtaaccagca taaccgccca acgttagcat tagcgttgca
     2401 acggcaaacg caatgatgta cagcgtgatg tggtttttag cgactgagat tccttttatc
     2461 accggcagaa ccgggatatt ggccgcctga tagtccttaa agcggaaaat ggcgatggcg
     2521 taagagtgcg gcatctgcca gaggctgaaa atagccaaca gaatcgccgc gccgctgtca
     2581 aagtcgcccg ttacggcgca gtagccaatc accggcggcg ctgcgccgga gagcgaacca
     2641 atcagcgttc cgtagacgga gtgacgcttc atgtacaagc tgtacacgcc aacgtagacc
     2701 acgaagccca tcacccccag ccagcaggcc aaaggattag cgccaaacca cagcagcata
     2761 aagccagcaa tacccagcag ggtggcgtat accagcgaga cgccaggaga aatcaggcct
     2821 ttgaccagca cccgattctt ggtcctttcc atcttcctgt cgatatccct gtcgatgtag
     2881 ttgttaaata cacaacccga cgccacaacc agtgacaccc cgaccagcgt atagatgaac
     2941 aggggatagt caatgctgcc ctttgaggcc agcagaaatc ccccgatcac cgagatcagg
     3001 ttgccaaaga tgatgcctgg tttcgttact tgcaggtatt gcttaaacat catactcgcc
     3061 gctcttagtg catcatcatg ttgtagttga ggttccacat aatccagatg gagcccacaa
     3121 ccaggatggc gatgatcagc acggtaaaga tgaaggccgt catgttccag ccttcatcag
     3181 atttggtgtt catgtgcagg aaacacacca gatgcaccaa aatctgcacc actgccattg
     3241 ccaggataga tcccagaata acggccggag aggcagcgcc ggtcatcacc atccagaatg
     3301 gaataaccgt caggatgacc gacaggataa agccggtcat gtacgttttt acgctgccgt
     3361 gggatgcgcc gccgctctcg gtagaatgac tcattacatc gcccccatca gataaacaac
     3421 agtgaatacg caaatccaaa tcacatccag gaagtgccag aacaggctca ggcacatgat
     3481 gcgggtacgg ttagtgctgg tcagaccgcg acgggcgact tgcaccatca gcaccgccat
     3541 ccagatcaaa ccggaagtga cgtgcagacc gtgcgtgccg accagcgcga agaacgcaga
     3601 caggaagccg ctgcgatccg ggcccatacc gttaacaatc aggtgatgga attcatagat
     3661 ttccatcccg ataaatccgg caccgaacaa gaaggtcaac gccagccagg agataacctg
     3721 gctcttgttg ttcttgtgca tggcgatcgc cgccatgccg taggtaatgg agctaaataa
     3781 cagcaggaag gtttcaacca gaacgaacgg cagttcgaaa atgtccttac ctgtcgggcc
     3841 gccagcggtg ccgttcacca gaacggcata ggtagcaaac agaatagaga acagaatgca
     3901 gtcgctcatc aggtagaccc aaaatccgaa gattttgttc tggcctgcgt catggtgccc
     3961 gtgttcgtgc gcgtgggcag tcgcgtgcgt taaagtatca gttgccattt ttcagccctg
     4021 ccttagtaat ctcatcgaaa tgctggtttt ccagtttttc gacttccggg accggcacgt
     4081 agtaatccac atcttcatca aagcttttta caatccagct gatgatcatg cctgcgaaac
     4141 ccactatcgc cagccaccag atatgccaga tcatggcgaa gccaaatacc gtcgcgaagg
     4201 cggcgataac aataccggca ccgctatttt tcggcatatg aatctcttca tactgtccag
     4261 gctgttggta cgcttcgcct ttttctttca tttcccagaa ggcgtcacgt tcgtgaacgt
     4321 gcggcacaac ggcaaagtta tagaacggcg gcggagacga ggttgaccac tccagcgtac
     4381 ggccacccca tgggtcgccg gtcagatcgc ggttctgatc gcggtcgcga atagaaacga
     4441 agatctgaat cagttggcac aggataccca gcgcaatcag cgcggcgccg gcggcggcaa
     4501 ccatcagcat cgtatggaac tgcggatcaa tttgctggct gaggcgacgg gtcatgccca
     4561 tgaagcccag tacgtacagc ggcataaagg ctacaaagaa accgataatc cagaaccaga
     4621 aggcgcgttt accccaggtt tcgttcagct tgaagccaaa cgccttcggc caccagtaag
     4681 tcatacctgc gaagcagcca aacaccacgc cgccgatgat cacgttatgg aagtgcgcaa
     4741 tcaggaacag gctgttgtgc aggacgaagt ccgcgcccgg taccgccagc agcacgccgg
     4801 tcataccgcc gaccgagaag gtcacgataa agccgatggt ccacatcatt gcggaatgga
     4861 agacgatacg gccctgatac atggtgaaca accagttgaa gatcttcacc ccggtcggga
     4921 tggcgataat catggtggtg ataccgaaga aggcgttaac gttcgcgccc gcgcccatcg
     4981 tgaagaagtg gtgcagccaa acgataaacg acagtacggt aatacagacg gtcgcccaaa
     5041 ccagcgaggt atagccgaac agacgtttac gcgagaaggt cgctgcgatt tcggagaata
     5101 ccccgaagac cggcagaatc agaatgtaca cttccggatg gccccaggcc caaatcaggt
     5161 tgatgtacat catcatgttg ccgcccatat cgttggtaaa gaaatgggtg cccagatagc
     5221 gatccagggt cagcaacgcg acggtaaccg tcagaatcgg gaaagaggcg atgatcagta
     5281 cgttggcgca caaagaggcc caggtaaaga ccggcatctt gaacattgtc atacccggcg
     5341 cacgcatctt caggatcgtc acgaagaagt tgataccggt taacgtcgta ccaatacccg
     5401 agagttgcaa cgcccatatc cagtaatcga ccccgacgct gggactgtac tctattcccg
     5461 atagcggcgg ataagccagc caccctgtct gcgcgaattc acccacgccc agcgagaggt
     5521 taaccagaat aacgccgaca acggtgaacc agaagctcag gttgttcagg aaagggaaag
     5581 caacgtcgcg cgcgccgatc tgcagcggaa ccaccaggtt catcagaccg ataacgaagg
     5641 gcatcgccac gaagaagatc atgattacgc cgtgagcggt aaagatctga tcgtagtggt
     5701 gcggcggtag aaaacccgct tcgcctgcgg aggcaagcgc ctgctggcta cgcatcatga
     5761 tggcatcggc gaaaccacgt aacagcatca caatcgcgac gatgatatac atgataccga
     5821 ggcgtttatg gtcaaccgac gttaaccact ctttccatag gtaggtccac ttaccgaagt
     5881 aagtaatcgc tgccagtatc gccagtcccc cgacgataat tgcagcgatc gttaccatga
     5941 cgataggttc atggaacggt actgcatcca gtgataattt tccgaacatc ttatcttcct
     6001 caacccttgg agttggcgga ttccgcgtgg ctcatgtcca taccttccat tccttcatgc
     6061 gagctgtgct caccttcagg ttgggtcatg tccatgctct taccgtggcc catgaatttg
     6121 ttaataacgt ccttgaacaa atctggtttc acgctggaga aatattccac cttgttgtac
     6181 tcgcttggca tagccacttt ctcgaacgcc gccatatcat tcatggtgtt cggagactgc
     6241 ttcgcttttg cgacccattg gtcgaattct gcgcggtctt tggtggcgat agctttaaac
     6301 ttcataccag agaagcccgg gccgctatag ctggcggaga tgccatcgta ggttccgggt
     6361 tcgttggcga tcagatgcaa acgtgtttgc ataccggcca tggcataaat ctggctaccc
     6421 agacgcggga taaagaagga gttcatcacg gagttggagg tcactttgaa ataaaccggc
     6481 gtgttcgccg ggaaggcgat ctcgttgacg gtggcgatac cctgctccgg atagatgaag
     6541 aaccatttcc agtccatgga aaccacttcg atggtgatcg gtttttcgtc atgcgccagc
     6601 ggcttgcttg gttcaagcgc gtgcgtggtt ttccaggtca gtacggcaag gaaaatgatg
     6661 attaagatag gcaccgtcca gaccacggct tccactttat tggagtgtga ccagttcggg
     6721 ctatacttcg catccttatt actcgcacga tacttccagg caaaaccaac agccatcaag
     6781 atggcgggaa taacgacgat caacatcagg ccaaatgccg tcagtatcag cgaacgttgc
     6841 tccagtccaa tctgtccttt gggatccagc agcgcagaat tacagccact gagtaatgca
     6901 gtgcctgcaa ttaatgacaa ccatcccaaa cttttattgt atttcctgag tctcatttaa
     6961 cgacctcaat tccacgggac ctggtggcgt ttaaagtgta ggggcatttt acggtaaggt
     7021 tacattactg taaacatgat tggttctgtg ttaccaagtt ctgccgcgcg tgtcacatat
     7081 gttgccaagt atgtcgaaat aactttaaga cactgttgaa actttgcgtt ataacggatg
     7141 aggtctgtaa gtgggatgtt gagggataat tggtataacc aatgtaaaaa taaaacaatt
     7201 acttaacaat ttattatcaa taaaaggaca atcaacggta gaaatttaaa tttagtcggc
     7261 tgaatcgtgt aaagaaaata ggtagcgtag aaattaccaa taatttccaa aattctgttg
     7321 c
//
LOCUS       DAJVBX010000210         7298 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.210, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000210 DAJVBX010000000
VERSION     DAJVBX010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 7298)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7298)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7298
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.210"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(61..591)
                     /gene="ppa"
                     /locus_tag="OPV72_003899"
     CDS             complement(61..591)
                     /gene="ppa"
                     /locus_tag="OPV72_003899"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001739810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic diphosphatase"
                     /protein_id="HCR9916072.1"
                     /translation="MSLLNVPAGKELPEDIYVVIEIPANADPIKYEVDKESGALFVDR
                     FMSTAMFYPCNYGYINHTLSLDGDPVDVLVPTPYPLQPGAVIRCRPVGVLKMTDESGE
                     DAKLVAVPHTKLSKEYDHIKDVNDLPELLKAQITHFFEHYKDLEKGKWVKVDGWDNAE
                     AAKAEIVASFERAAKK"
     gene            complement(818..1816)
                     /gene="fbp"
                     /locus_tag="OPV72_003900"
     CDS             complement(818..1816)
                     /gene="fbp"
                     /locus_tag="OPV72_003900"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1 fructose-bisphosphatase"
                     /protein_id="HCR9916073.1"
                     /translation="MKTLGEFIVEKQHEFSQATGELTALLSAIKLGAKIIHRDINKAG
                     LVDILGASCAENVQGEVQQKLDLFANEKLKAALKARDIVAGIASEEEDEIVVFEGCEH
                     AKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRVTPVGTPVTEEDFLQPGNKQVAAGYVV
                     YGSSTMLIYTTGCGVHAFTYDPSLGVFCLCQERMRFPEKGKTYSINEGNYIKFPNGVK
                     KYIKFCQEEDSSTSRPYTSRYIGSLVADFHRNLLKGGIYLYPSTASHPQGKLRLLYEC
                     NPMAFLAEQAGGKASDGKERILDIIPESLHQRRSFFVGNRHMVDDVERFIREYPDA"
     gene            1991..3364
                     /gene="mpl"
                     /locus_tag="OPV72_003901"
     CDS             1991..3364
                     /gene="mpl"
                     /locus_tag="OPV72_003901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-
                     meso-diaminopimelate ligase"
                     /protein_id="HCR9916074.1"
                     /translation="MRIHILGICGTFMGGLAMLARSLGHEVTGSDANVYPPMSTLLEK
                     QGIDLIQGYDASQLDPQPDLVIIGNAMTRGNPCVEAVLEKNIPFMSGPQWLHDFVLRD
                     RWVLAVAGTHGKTTTAGMATWILEACGYKPGFVIGGVPGNFEVSARLGESPFFVIEAD
                     EYDCAFFDKRSKFVHYCPRTLILNNLEFDHADIFDDLKAIQKQFHHLVRIVPGQGRII
                     WPENDINLKQTMALGCWSEQELVGEQGHWQAKKLTTDTSEWEVWLDGEKVGDVKWGLV
                     GEHNMHNGLMAIAAARHVGVAPAEAASALGSFINARRRLELRGEANGVTVYDDFAHHP
                     TAILATLAALRGKVGGTARIIAVLEPRSNTMKMGLCKDDLAPSLGRADEVFLLQPPHI
                     PWQVSEVADACVQPAHWSGDVDTLADMVVKTAQPGDHILVMSNGGFGGIHQKLLDGLA
                     KKALVVG"
     gene            complement(3471..4022)
                     /locus_tag="OPV72_003902"
     CDS             complement(3471..4022)
                     /locus_tag="OPV72_003902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated protein"
                     /protein_id="HCR9916075.1"
                     /translation="MTKQPEDWLDDVPGDDIEDEDDEIIWVSKSEIKRDAEELKRLGA
                     ELVDLGKNALDKIPLDADLRDAIELAQRIKMEGRRRQLQLIGKMLRQRDVEPIRQALD
                     KLKNRHNQQVVLFHKLEHLRDRLIVEGDDAVAEVLTLWPHADRQQLRSLIRNAKKEKE
                     GNKPPKSARQIFQYLRELAENEG"
     gene            4118..5470
                     /gene="pmbA"
                     /locus_tag="OPV72_003903"
     CDS             4118..5470
                     /gene="pmbA"
                     /locus_tag="OPV72_003903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloprotease PmbA"
                     /protein_id="HCR9916076.1"
                     /translation="MAFAMKVISQVEAQRKILEEAVSTALELASGKSDGAEVAVSKTT
                     GISVSTRYGEVENVEFNSDGALGITVYHQNRKGSASSTDLSPQAIARTVQAALDIARY
                     TSPDPCAGVADKELLAFDAPDLDLFHPAEVTPDEAIELAARAEQASLKADKRITNTEG
                     GSFNSHYGIKVFGNSHGMLQGYCSTRHSLSSCVIAEENGDMERDYAYTIGRAMADLQA
                     PEWVGAECARRTLSRLSPRKLSTMKAPVIFANEVATGLFGHLVGAIAGGAVYRKSTFL
                     LDSLGKQILPEWLTIEEHPHLLKGLASSPFDSEGVRTERRDIVKDGVLTQWLLTNYSA
                     RKLGLKSTGHAGGIHNWRIAGQGLNFEQLLKEMGTGLVVTELMGQGVSGITGDYSRGA
                     AGFWVENGEIQYPVSEITIAGNLKEMWRNIVTVGDDIETRSNIQCGSVLLPEMKIAGQ
                     "
     gene            5568..5954
                     /gene="cybC"
                     /locus_tag="OPV72_003904"
     CDS             5568..5954
                     /gene="cybC"
                     /locus_tag="OPV72_003904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b562"
                     /protein_id="HCR9916077.1"
                     /translation="MRKSLLAILAVSSLVFGSAVFAADLEDNMDILNDNLKVVEKTDS
                     APELKAALTKMRAAALDAQKATPPKLEDKAPDSPEMKDFRHGFDILVGQIDGALKLAN
                     EGNVKEAKAAAEALKTTRNTYHKKYR"
     gene            6232..6570
                     /locus_tag="OPV72_003905"
     CDS             6232..6570
                     /locus_tag="OPV72_003905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine dehydrogenase"
                     /protein_id="HCR9916078.1"
                     /translation="MRRVDNGAVKHDAGERINELAEQVLTQVDGLLGRHHIVPNAVQT
                     QMLTSHVRAMAHRSITGEPLPEVDASLFDEISAESMALAREIVAAFGNLPDEEAWLLS
                     VHFEVAKDNL"
     gene            6581..6943
                     /locus_tag="OPV72_003906"
     CDS             6581..6943
                     /locus_tag="OPV72_003906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916079.1"
                     /translation="MEQITVVIGDRLGKGQKVAAGVEKAGGRAVVVPGVAADMKLGDV
                     MKAENATFGISFCGSGGAGAITAQNKHGYKAKYGMRSVDEGVTAINEGCNVLGFGFMD
                     KEELGERLVQAWQKKYGA"
     gene            6943..7245
                     /locus_tag="OPV72_003907"
     CDS             6943..7245
                     /locus_tag="OPV72_003907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4312 family protein"
                     /protein_id="HCR9916080.1"
                     /translation="MMKEQFTTTVRVKGKGDAKARAFADALNHVQSAVMRESPYILLR
                     IEPQDVRIVQAHESVRKEAFLFFFLRRERRTYSVELDVAVNVTAINLDRVDFVAKR"
BASE COUNT         1699 a         1840 c         2061 g         1698 t
ORIGIN      
        1 caataaaaag gccctcatta ctatgagagc ctttatcttg acgattatgt aaaagcgaac
       61 ttatttcttc gctgcgcgct cgaaagaggc aacgatttcc gctttagccg cttcggcgtt
      121 gtcccaaccg tcaactttca cccatttgcc tttttcgaga tctttataat gctcgaagaa
      181 atgagtgatc tgcgctttca gcagttccgg cagatcgttc acatctttaa tgtgatcgta
      241 ctctttgctc agtttggtgt gcggtacggc aaccagtttc gcatcttcac cggattcgtc
      301 ggtcattttc agtacgccaa ccggacggca acggatgacg gcgcctggct gcagcgggta
      361 cggcgtcggg accagaacgt ctaccgggtc gccgtccaga gacagggtat ggttgatgta
      421 accgtagttg cacggataga acatcgcggt ggacatgaag cggtcaacga acagcgcgcc
      481 gctctctttg tcaacttcgt atttgatcgg atctgcgtta gccgggatct cgataacgac
      541 gtagatatct tccggcagtt ctttacccgc cgggacgttg agtaagctca tgtctgtttc
      601 ctttgaagtt atgacaaaca agtggcgagt attatagcca actcacgccg aaagtcttcg
      661 cttgttttcg tttccgcctc atctggcgcg tcgttgcgga gcataaacga caaaggttaa
      721 gaaccgaaaa aatcacgggc ctgataaggc aacgccgcca tcggacatct tattgcccaa
      781 tggcggcttc atgcgttatt ccgcatggtg gtaaagatta cgcgtccggg tattcgcgga
      841 taaagcgttc cacatcgtca accatatggc ggttgccgac gaagaacgag cggcgctggt
      901 gcaggctttc cggaatgata tccagaatac gttctttacc atcgcttgct ttgccaccgg
      961 cctgttccgc gaggaacgcc atcgggttgc attcatacag cagacgcagt ttcccctgcg
     1021 gatggctggc ggtgctgggg tagagataga tgccgccttt cagcaggttg cggtggaaat
     1081 cggccaccag agagccaatg taacgtgagg tataagggcg acttgttgaa ctatcctctt
     1141 cctggcagaa tttgatgtac ttcttcacgc cattcgggaa cttaatgtag ttgccttcgt
     1201 taatggagta ggttttaccc ttttccggga aacgcatacg ttcttggcac agacagaaca
     1261 cgcccaacga cggatcgtag gtgaaagcgt gtacgccgca gccggtggtg taaatcagca
     1321 tggtggacga gccatacacg acatatcccg cagcgacctg tttgttgccg ggttgcagga
     1381 aatcttcttc ggtgaccggc gtgccgacgg gcgtcacgcg gcgataaatc gagaaaatcg
     1441 taccgacaga gacgttaacg tcgatgttag aagagccatc cagagggtcc atcagcacca
     1501 catatttcgc gtgttcgcag ccttcaaaga cgacaatttc gtcctcttct tccgatgcga
     1561 tgcccgctac aatatcgcgc gcttttagtg cagctttcag tttctcgttc gcgaacagat
     1621 cgagtttctg ctgaacctcg ccctgtacgt tctcagcaca gctggcaccc aggatatcga
     1681 ccagaccggc cttgttgata tcgcggtgga tgatcttggc gcccaatttt attgccgaca
     1741 gcaaagcagt gagctcaccg gtagcctgag agaactcgtg ctgcttttcg acaataaatt
     1801 cacctaacgt tttcataaca ctttccctgc aattgattgg agtaaagcga ccgtaacaat
     1861 cttaacaaac atttcagatg atgcgctcag gtgaatcgcg ccagcaaagt acagatttac
     1921 ctgaaatgcg tttctcactt gccagacatg tgcgtaaaat ggctcgcaga taaaaaaagg
     1981 atagtgacgt atgcgcattc atattttggg aatttgtggc actttcatgg gggggctggc
     2041 gatgctggct cgctcgcttg gtcatgaagt aacgggttcg gacgccaatg tgtatccgcc
     2101 gatgagtacc ttacttgaga agcaaggcat tgatctgatc cagggttatg acgccagcca
     2161 gctcgatccg cagccagatc tggtgattat cggcaatgcg atgacgcgcg ggaatccgtg
     2221 cgtggaagcg gtgctggaaa aaaacattcc ctttatgtct ggtccacagt ggctgcatga
     2281 ctttgtgttg cgcgaccgct gggtactggc ggtcgccggt acccacggta aaaccacgac
     2341 cgcaggcatg gcgacctgga tactggaagc gtgcgggtac aaaccgggct tcgtgatcgg
     2401 cggcgtaccg ggcaattttg aggtttccgc acgcctgggc gagagcccat tctttgttat
     2461 cgaagcggat gagtacgact gcgcgttctt tgataaacgt tctaaatttg tgcattactg
     2521 cccgcggacg ctgatcctca acaaccttga gtttgatcat gccgacatct tcgacgatct
     2581 gaaagcgatc cagaagcagt tccaccacct ggtgcgcatc gtgccggggc aggggcgcat
     2641 catctggccg gaaaacgaca tcaacctgaa acagaccatg gcgctgggct gctggagcga
     2701 gcaggagctg gtgggcgagc agggacactg gcaggcgaag aagctgacta cggatacttc
     2761 cgagtgggaa gtgtggctgg acggcgaaaa agtcggcgat gtgaaatggg gcctggtcgg
     2821 cgaacataac atgcacaacg gtctgatggc gattgccgcc gcgcgccacg tgggcgtcgc
     2881 gcccgcagaa gcagccagcg cgctggggtc atttattaac gctcgccgcc gtctggagct
     2941 acgcggtgaa gcgaacggcg tgacggtgta tgacgatttt gctcaccatc ctacggcaat
     3001 tctggccacg ctggcggcgc tgcgcggtaa agtgggcggc accgcgcgca ttatcgcggt
     3061 actggagccg cgttctaaca cgatgaagat ggggttatgc aaggatgacc tggcgccgtc
     3121 gttagggcgt gcggatgaag tgttcctgct gcagccgccg catattccgt ggcaggtttc
     3181 agaagtggcg gacgcctgcg tacagcctgc tcactggagt ggagatgtcg atacgctggc
     3241 ggatatggtg gtgaaaaccg cacagcctgg cgatcacatc ctggtgatga gcaacggcgg
     3301 tttcggcggc atccatcaga aattgctgga tgggctggcg aaaaaagcac tggttgtggg
     3361 gtaaaaaatg cccggtggcg ctgcgcttac cgggcctaca atacgtacat tcccgtaggc
     3421 cggataaggc gttagcgccg ccatccggca gacgctatca acatgtaaaa ttacccttcg
     3481 ttttccgcca gctcgcgcag atactggaag atctgacgcg ctgatttcgg cggtttgttg
     3541 ccttctttct ctttcttcgc attgcggatc aatgaacgaa gctgttgacg atcggcgtgc
     3601 ggccacaggg tcagtacttc ggctaccgcg tcatcgcctt cgacgatcag acgatcgcgc
     3661 agatgctcaa gcttgtgaaa cagcaccacc tgctgattat ggcggttctt cagcttgtcc
     3721 agcgcctggc gaataggttc aacgtcgcgt tggcgcagca tttttccgat aagctgcaac
     3781 tggcggcggc gtccttccat tttgattcgc tgggccagtt caatggcgtc gcgcagatcg
     3841 gcgtccagcg ggatcttatc cagcgcgttt ttccccagat ccaccagttc cgcgcccagg
     3901 cgttttaatt cctcggcatc gcgtttaatt tcacttttac tgacccagat aatttcatcg
     3961 tcttcgtctt cgatgtcatc accgggaacg tcgtcgagcc agtcttcggg ctgctttgtc
     4021 atgtcaggct ccttaaaaaa agaggctaat gttaccagtt aagatgcgca ctgaaaaacg
     4081 gttctctgtt agacttcaga gaaactctct ctacattatg gcatttgcaa tgaaagtaat
     4141 ctcacaagtt gaagcgcagc gtaagattct ggaagaagca gtttcgacag cgctggagtt
     4201 agcctcaggc aaatcggatg gggcggaagt cgccgtcagc aagactaccg gcattagcgt
     4261 cagcacccgt tatggtgaag tagagaatgt cgaatttaat agcgacggcg cgctgggaat
     4321 tacggtgtat caccagaacc gcaaaggcag cgcctcttcg acggatttaa gcccgcaggc
     4381 gattgcccgt accgtgcagg ccgcgctgga tatcgcgcgt tacacgtcgc cggacccgtg
     4441 cgcaggcgtg gcggacaaag aactgctggc gtttgacgcg ccggatctgg atttgttcca
     4501 cccggcagag gttacgccag acgaagccat tgaactggcc gcgcgtgcgg aacaggcttc
     4561 tctaaaggcg gataaacgca tcaccaatac cgaaggcggt agctttaaca gccattacgg
     4621 cattaaagtg ttcggcaaca gccacggtat gttgcaggga tattgctcca cgcgccattc
     4681 gctctcaagc tgcgtcatcg ccgaagagaa cggcgatatg gagcgtgatt acgcttacac
     4741 catcggccgg gcaatggcgg atctgcaagc gccggaatgg gtcggggccg agtgcgcgcg
     4801 ccgtacctta tcccgcctgt cgccgcgcaa gctctccacc atgaaagcgc cggtcatttt
     4861 cgccaatgaa gtggcgacag ggctatttgg tcatctggtc ggggcgattg ccggcggcgc
     4921 ggtataccgt aaatccactt ttctgctcga ctcgctgggc aaacaaattc tgccggaatg
     4981 gttaaccatc gaagaacacc cgcatctgct aaaagggctg gcgtcttcac cgttcgacag
     5041 cgaaggcgtg cgtacggagc gccgggacat tgtgaaggat ggcgtactga cgcaatggtt
     5101 gctgaccaac tattccgccc gcaaactggg gctgaaaagt accggtcatg ctggcggcat
     5161 tcataactgg cgtatcgccg ggcaggggct gaactttgag cagttactga aagagatggg
     5221 taccggcctg gtggtgacgg aactgatggg ccagggcgtc agcggtatta ccggcgacta
     5281 ctcccgcggc gctgcgggat tctgggttga aaatggtgaa atccagtacc cggtaagtga
     5341 aattaccatt gccggtaatt taaaagagat gtggcgtaat attgtcaccg taggcgatga
     5401 tattgaaacg cgcagtaata tacaatgtgg ttcggtattg ttaccggaga tgaaaatcgc
     5461 cggacaataa tacccgtcat acttcaggct gcaggcgcgt tggctgcctg caactcgaat
     5521 tattcagggt attacactta tcgttaataa taaaaaggaa gtgagcaatg cgtaaaagcc
     5581 tgttagctat tcttgctgtg tcatcgctgg tattcggttc ggctgttttt gctgccgatc
     5641 ttgaagataa tatggatatt ctcaatgata acctgaaagt tgttgagaaa acggatagtg
     5701 cccctgagct gaaagcggca ttaactaaaa tgcgcgcggc cgcgctggat gctcaaaaag
     5761 ctacgccgcc aaagctggaa gataaagcgc cggatagccc ggaaatgaag gattttcgtc
     5821 acggttttga cattctggtc ggccaaattg atggcgcgct gaagctggcg aacgaaggta
     5881 acgttaaaga agcgaaagcg gcggcggaag cgctaaaaac cacccgcaat acgtatcata
     5941 agaagtatcg ttaatttttg tgggatggcg gcttcgcttt atccgcaggt cgccatccgg
     6001 caaaatgtaa tacccatcac actttctcac tttatacgac aacgtcattg tttcgccatt
     6061 tcctctttat gccgcgatag atctcacact ttcccggcga taattcatca atgccgcttt
     6121 ttctgtggcg cagatcacct atcccactcg cgtttccact tcgaggtgga aaataactcg
     6181 ctacaaactt ttaaccctta ccgctagttt tatctcattg ccattaatgg ggtgagacgc
     6241 gtggataacg gagcagtaaa acacgatgcc ggtgagcgaa ttaacgaact ggctgaacag
     6301 gtgttaacgc aggtggatgg cctgctgggg cgacatcaca ttgtccccaa tgcggtacag
     6361 acgcaaatgc tgacctcgca cgttcgcgcg atggcgcacc ggtcaattac cggcgagcct
     6421 ttaccggaag tcgatgccag cttgtttgat gaaatctcag ccgaatcaat ggcgctcgcc
     6481 cgcgaaatcg tggcggcgtt tggcaacctt cctgacgaag aagcctggct attatcggta
     6541 cattttgaag tcgcgaaaga caacctctaa ggagcaaaaa atggaacaga ttaccgtcgt
     6601 aattggcgat cgcctgggta aaggccagaa agtggcggca ggcgtggaaa aagcgggcgg
     6661 tcgcgcggtc gtcgtaccgg gcgtcgcggc agacatgaag ctgggcgatg tgatgaaagc
     6721 ggaaaacgcc accttcggca tttcattttg cggcagcggc ggcgcgggcg ctatcaccgc
     6781 gcaaaacaag catggctaca aagccaaata tgggatgcgg tcagtagatg aaggagtcac
     6841 cgctatcaat gagggctgca acgtgttggg tttcggcttt atggataaag aagagctcgg
     6901 cgagcgcctg gtgcaggcgt ggcaaaagaa atacggcgcc tgatgatgaa agagcaattc
     6961 accaccacgg tgagagtaaa aggcaagggc gacgccaaag cacgcgcctt tgccgatgcg
     7021 ctgaaccatg ttcagtcggc ggtgatgaga gagtcgccgt atatcttact gcgtattgag
     7081 ccacaggatg tgcggattgt tcaggcgcat gagtcggtgc gtaaagaggc ctttctgttt
     7141 ttctttttgc gccgggaacg acgcacttac agcgtggagc tggatgtggc cgtcaacgtg
     7201 accgccatca atctcgacag ggtggatttc gtcgcgaaac gctgattttt attaaaaagg
     7261 catagttatg ttcctgataa tactaattaa atctctca
//
LOCUS       DAJVBX010000211         7291 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.211, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000211 DAJVBX010000000
VERSION     DAJVBX010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 7291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7291
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.211"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(152..1057)
                     /locus_tag="OPV72_003908"
     CDS             complement(152..1057)
                     /locus_tag="OPV72_003908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiK family protein"
                     /protein_id="HCR9916081.1"
                     /translation="MRYDISRDAICYGFFMRLLKRVIVVVLLGVILFMVRDDIRYVYQ
                     LILKYGDKPSALALSSYKAVIQQKPVAGVKSNLSGLTYSAEDRMLFAVINNPPELVWL
                     TTEGQLVGRMPLQGIHDPESIAWSGGNQFQIGSEKDGAVYKTQVDIQRGAMQIISMVK
                     LEGYDKAKNKGLEGTAWDAKNERLYAAKERKPIMIKEVEMSKNGITRALPSAITASVS
                     DVSGLEYHAPTDSLLVLSDESKMILEVSSEWRVRDRLFLTAEWSGLRDDIPQPEGIAM
                     DNENNLYIVSEPNLFYKFSCDIQND"
     gene            1361..2761
                     /locus_tag="OPV72_003909"
     CDS             1361..2761
                     /locus_tag="OPV72_003909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1996 domain-containing protein"
                     /protein_id="HCR9916082.1"
                     /translation="MKLNLITVSLATLVAAGAFPAHAGPQAHVVCGYHHTLGDDAIMM
                     FGKANQAMWHDFFGNTHTDAVSTYQTLRAQPDTTCDNKADSSGYWAPSMKLPDGEIVN
                     PAYQKTYYQSTNVAQYPLHPFPAGLELLAGDHHGTGPSSAITFLCANGKGYTNKVGEI
                     CGLRKAGDAVQFNIGIAFPNCWDDVNLKPTHSHNNAIYADHGKCSADYPVKIPTVNMN
                     IAWVLPQISSLDTSKVELSMDPVMHGETREERWGSIYTAHADFMNGWTEDGAQFMTDL
                     CMNQGLDCGTAVPYAYSKAEENTWVSSEDDKPHASVDTLYVQDDWTNGGRTQHPETLT
                     LVKFKIPPLPANMDASLFKYRIRLFGGKTETNGADQIFFYPTSSDWHASSVSWNNKPA
                     INYRSDAVLYLNHSHEYRMVDVDKAVRKALAEGKTEISWYIGGDRQGNHYDFMPADSK
                     QSLVLMLTGFKKTPEL"
     gene            complement(2845..3498)
                     /locus_tag="OPV72_003910"
     CDS             complement(2845..3498)
                     /locus_tag="OPV72_003910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HCR9916083.1"
                     /translation="MPCKPDKRSVIRRNISGAIAMPSRAVLPRILGALFYYSPERPEV
                     KALFDCLPTLPELYPWRDRGHIESLCASWSLPDDDALTWQFSVLFEGQGKMPVPPWGS
                     VYLEKDNLLMGETTADYRAFLQSQGMVFTDREREPEDQFGLMLLACSDLLAQGDNVAA
                     NRLLEAHLLPWGFRYLELLQRNTVSAFYARLAIVATCYLQDVQQQQGLQPEKKRLFF"
     gene            complement(3513..4286)
                     /locus_tag="OPV72_003911"
     CDS             complement(3513..4286)
                     /locus_tag="OPV72_003911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase anchor subunit
                     family protein"
                     /protein_id="HCR9916084.1"
                     /translation="MHELPLVFFTVFTQSAVGAFILLLIGGAMGLVAPRRKAIGLFSV
                     MCLFGIGVVVGTFHVGQPLRALNMLLRVGHSPMSNEIVLSAAFVALGGLGALGLLLNR
                     ATPLCNALVWLAAIVGVVFLYAVPQIYQLPTVATWRSSYTTAMMILTPLIGGGALAAL
                     FGVRRLGLLVSVLAILVSFCLRPGYMATLMSADSALTAAQHSWFTAQAVLLAAGVVGV
                     VVCARLKSSATVLAMTAVVVIAAELAGRIAFYNLWTLPM"
     gene            complement(4279..4905)
                     /gene="dmsB"
                     /locus_tag="OPV72_003912"
                     /pseudo
     CDS             complement(4279..4905)
                     /gene="dmsB"
                     /locus_tag="OPV72_003912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463171.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dimethylsulfoxide reductase subunit B"
     gene            complement(4919..7291)
                     /locus_tag="OPV72_003913"
                     /pseudo
     CDS             complement(4919..7291)
                     /locus_tag="OPV72_003913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403483.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
BASE COUNT         1788 a         2062 c         1799 g         1642 t
ORIGIN      
        1 ttaccgttac gctacaccac aaagtaatcc gttactgagg taagtaaaac ataaatatcc
       61 ccaacaatga atcaacaaat caagcaatcg tcaaatcatg gtattaacaa ccttgttctg
      121 ttttagcatg ctgtgacagt aaaaatagat tttagtcatt ctgtatatca cacgaaaatt
      181 tataaaacag atttggttca ctcacaatat acaaattatt ttcattatcc atggcaatcc
      241 cttctggttg gggtatatcg tctctgagcc ctgaccactc cgccgtcagg aacaatcgat
      301 cgcgcacccg ccactcggaa ctgacctcca gaatcatttt tgactcgtcc gacaacacca
      361 gcagcgaatc cgttggggca tggtattcaa gtccggagac atcgctcaca ctcgcagtga
      421 tggcagaagg caacgctctg gtgataccat ttttgctcat ctctacttct ttgatcataa
      481 tgggttttct ttcttttgcg gcatataatc tctcattttt cgcatcccat gccgtacctt
      541 ccagcccttt attttttgct ttgtcatagc cctcaagctt caccatggag attatctgca
      601 tagcgccgcg ctgaatatcc acctgtgttt tatagaccgc gccatctttc tcactgccta
      661 tctggaactg gttgccccca ctccatgcaa tagactccgg gtcgtggatg ccctgcagcg
      721 gcatccgccc taccagctgc ccttctgtcg ttaaccagac cagttcaggg ggattattaa
      781 taacggcgaa aagcatcctg tcttcggcgg agtaggtcaa acctgaaagg ttactcttaa
      841 ctcctgcgac tggtttttgc tgaataaccg ctttatagct actcagtgct agcgccgagg
      901 gtttatcacc atatttgagg atcagttgat aaacatagcg tatatcgtcc ctgaccataa
      961 ataaaatcac gcccaagagt acaaccacaa taacgcgttt tagtaatctc ataaaaaatc
     1021 catagcagat cgcgtcacga ctgatgtcgt aacgcatttc ttaaaaataa agccgatgtc
     1081 cgatagaatc gttattcggt tatggcgagc gccattagca taggcaaaat gaaatagtga
     1141 gggttatcac aaaaagcccg attttaatca ctaacgtacc ctttttgtaa attgacataa
     1201 tcaagaggag ggtagtttcg gctaattatt taaatagtac gtctgcaaat tcgcccctgt
     1261 atgcagggca aatgacaaaa agtgataatt aatgagatgt aacaccgtaa tttgatctgc
     1321 tattgctgct cccacttcta ttcaaccggg cagcaaaaaa atgaaactca accttattac
     1381 cgtcagcctg gctacgctcg ttgccgctgg cgcattcccg gcccatgccg gtcctcaggc
     1441 gcatgtcgtg tgcggctatc accacacgct gggcgatgac gcgattatga tgtttggtaa
     1501 agcgaatcag gcgatgtggc atgacttttt tggcaacacc cacaccgacg cggtctctac
     1561 ctaccagacg ttgcgcgcgc aacccgatac cacctgtgat aataaagccg acagctccgg
     1621 ttactgggca ccgtccatga aattacccga tggtgaaatc gtaaatccgg cctaccaaaa
     1681 gacctattat caatccacaa atgtagcgca atatccgctc catccattcc cggccgggct
     1741 ggagttactg gcaggcgatc atcacggtac tggccccagt tccgcaatca cctttttatg
     1801 tgccaacggc aaaggttaca ccaacaaggt aggcgaaata tgcggcctgc gtaaagcggg
     1861 cgatgccgtc cagtttaata tcgggatcgc tttccccaac tgttgggatg acgtcaacct
     1921 gaaaccgaca catagccaca ataatgctat ctatgccgac cacgggaaat gttccgcaga
     1981 ctatccggtt aaaatcccga cggttaatat gaacatcgcc tgggtactcc cgcagatctc
     2041 ctcgctggat acgtccaaag tggaattgtc gatggacccg gtaatgcatg gcgaaacccg
     2101 ggaagagcgc tggggaagta tttataccgc ccatgccgat tttatgaatg gctggacgga
     2161 agatggcgcg cagtttatga cggatctgtg tatgaatcag ggactggatt gcggcactgc
     2221 ggttccttac gcctacagta aagcggaaga aaatacctgg gtaagcagcg aagacgacaa
     2281 gcctcatgcc agcgtcgata cgttgtacgt acaggatgac tggacaaatg gcggacgcac
     2341 gcagcacccg gaaacgctca cgctggtgaa atttaagatc ccgcccctgc ctgccaatat
     2401 ggacgcttcg ctattcaaat accgtattcg cctttttggc ggcaaaacgg aaacgaacgg
     2461 cgccgatcaa attttctttt acccgaccag cagtgactgg cacgccagta gcgtgtcatg
     2521 gaacaataaa ccggcgatca attaccgttc cgatgccgta ttatatctaa accattcaca
     2581 tgagtatcgc atggttgatg tcgataaagc ggtgcgcaaa gcgctagcgg aagggaaaac
     2641 ggaaatatcc tggtatatcg gcggcgaccg tcagggaaat cactacgatt tcatgccagc
     2701 ggactcaaaa cagagcctgg tgctgatgct gaccggtttc aaaaagacgc cggagctgta
     2761 atagtaaact gtgcccgctg acgcaacagc gggcacgatg gcgacacaag cattacggca
     2821 cgtcgtcaaa acctgaccaa taccttagaa aaacaaccgt ttcttctcag gttgtagccc
     2881 ctgttgctgc tgaacatcct gcagataaca ggtcgctacg atggcaagcc gggcatagaa
     2941 ggcgctaacg gtattgcgtt gcagcaattc cagatagcgg aatccccagg gtagcagatg
     3001 cgcctccagt aaccggttgg ccgccacgtt gtcgccttgc gccagcagat cgctacaggc
     3061 taatagcatc aggccaaact gatcttccgg ctcgcgttca cggtcagtga ataccattcc
     3121 ctgcgactgt aaaaaagctc gataatcggc ggtggtttcc cccatcagca aattatcttt
     3181 ttccagatag accgatcccc agggcgggac gggcatcttt ccctggcctt caaacaatac
     3241 ggaaaattgc catgtaagcg catcatcatc cggtagcgac catgacgcgc acagtgattc
     3301 aatatgtccg cgatcgcgcc aggggtaaag ctcaggcaac gttggcaaac aatcgaacaa
     3361 cgctttcacc tccggcctct caggggagta gtaaaacagt gcgccgagga tacgcggcaa
     3421 aacagcacgg gaaggcatag caatagctcc tgaaatattt cgcctgatga cgctacgctt
     3481 atcaggctta catggcacaa gccgggcaaa aactacattg gcagcgtcca cagattgtaa
     3541 aacgcaatcc tacccgccaa ctccgccgcg ataaccacca cagccgtcat ggccagcacc
     3601 gtagcactcg atttcaggcg cgcgcagacc accaccccga ccacgcccgc cgccagcaat
     3661 accgcctggg cggtaaacca gctatgctgc gcggcggtca gagcgctatc ggcgctcatc
     3721 agcgtcgcca tatagcccgg gcgcagacaa aagctcacca aaatcgccaa cacgctgacc
     3781 agtagcccca gacggcgcac gccaaacaat gccgccaacg cgccgccgcc aatcaacggc
     3841 gtcaatatca tcattgccgt ggtgtaagat gaacgccagg tcgccaccgt cggcagttgg
     3901 taaatctgcg gaacggcgta taagaagacc accccgacta tcgccgccaa ccagaccaac
     3961 gcgttacaca gcggcgtcgc acggttcagc aataaaccga gcgcccccag accgccgagc
     4021 gccacaaaag ccgccgacaa gacaatctcg ttactcatcg gcgaatgtcc gacgcgcagc
     4081 agcatattca gcgcacgcaa cggttgcccg acgtggaagg taccgacaac gacgccaatc
     4141 ccaaacaggc acatcaccga gaacagaccg atagccttac gccgcggcgc gaccagcccc
     4201 attgcgccgc caatcagcag cagaataaac gcgccgaccg cgctctgggt aaagaccgta
     4261 aaaaagacca gcggtaactc atgcatggcg cacctcccga atgttcatga ttgcgccttc
     4321 cgtatcgccc gtgggtctcg ctttcggatg cggtttaata atgaggttag gatgggtgaa
     4381 cgacgccgaa ggcagcggcg cgatttgatt ctccgtgcca tattttgccc gtaattcatc
     4441 gacagggccg aaatccagcg ctcgctgcgg gcaagaatcc acacaaatgg ggcgcagatt
     4501 gttctccagt cagtcaagac aaccgtcgca tttacgcatc acgtttgcct gcgtatcaaa
     4561 ctgcggcgcg ccgtaggggc agcgcatttc acaatagcga cagccgacgc atacgctgtc
     4621 atccaccacg accagaccat cttctttgcg tttatgcatc gccccggtcg gacagccgga
     4681 gacacatacc ggctcatcgc aatggttaca agcaatagag aggtagtagg taaaggtgtc
     4741 gtgatgccag ctttccccct ctttcaccca gcttccgccg ccatattcat agacgcggcg
     4801 cagtttcggg ccgacatcca gatctttatt atccttgcag cttacctggc aggttttaca
     4861 gcctgaacag cgcgaggagt caacataaaa gccacactgt ttcatcgtac atcactcctt
     4921 aagcgcgttt aatttcaacc agattggtat gctgcggatt gcctttcgcc agcggcgaag
     4981 ggtgatggct ggtcagcgta ttgatacagc cgccgacatc aacaccgttg ccgtcaagcc
     5041 gcgtccacgc gccctgcggc atcgccgcca cgccgggtaa aatgcgctgg gtaactttac
     5101 agggaagctc caccacgccg cggtcattga atacatgcac ccgatcgccg gacttcagtt
     5161 ggcgggcgct ggcgtcaatc gggttaatcc agacttcatc cggcaccgcc tcatgcagca
     5221 tcagcacatt gctgtaggtc gagtgggtat gccctttggt atggaaaccg cttaactgca
     5281 acggatactt cgccgtcaat gctttgttaa ggtgcgactc tttcgctgga caaaattccg
     5341 gcaatgcggg aattcgctcg ccttctggca acgtccacgc ttgcgccaga tccgccagcg
     5401 cctaggagta aatttcaatt ttgcccgacg gcgtggagag tggattagcc tcggcgtcgg
     5461 cgcggaaatc agcaaacgca aggctctgct gctcggtagc gatacgctgg tcaatcacgc
     5521 ccatctcttt cgccacgctc cactccggca ggtatggacg tttttcacgg atctgctgat
     5581 agtgcatctc cgcccactgc gcctgagttc ggccctcggt atattgctcg cgcagtccaa
     5641 gatgcccggc gatatccgcg cagatgtcat acgtgctgcg cacttcccac atcggtttaa
     5701 cggttttctg aatcgcaatc atatagttat gcgatcctgc cgcataggag ctgtccacca
     5761 ggtcttccgc ctcaagatag ctggtctccg gcaacagcag atccgcatac atcgcgctgg
     5821 gcgtcatatg gttttcaatc acgataatgg tttcacacag cgattcatcc gcgagaattt
     5881 gacgggtgcg gtttgtttcg ccgtgctgat taagcaaagt attaccggcc tggttgaaaa
     5941 acagcttaat cccggttttt agcctgtccg cgccttttac gcccattgtc gtcgcggtca
     6001 ttttctccgg atgctgaatg gcgtccgtcc acagatagca aggaatagag gttgtgatcg
     6061 gattcttacc gacaggcaac aatggcacgc catacggcgt accgtaaggc cagttgccat
     6121 tattggtgcc gggccgcccg aagtggccgg ttaacgctgg cagcgtctga atagcacgca
     6181 cggtttgttc gccgttggca tgacgctgcg gcccccagcc ctggcaaata tagcaggcgc
     6241 gcgcgaggcg atttcgcgcg ccagttggcg aatacgcgtt gccggaattc cggtgatatc
     6301 cgccgcccat tccggggttt tcgcgatacc gtcatcgccc gtgccaagaa cataatcttt
     6361 atagctggcg ttaggcgcag ccgtgtccgg caaggtgcta cggtcatagc cgacgcaata
     6421 gcggtttacc agcgcctcgt cgagaagctg ttcggtaatc agcgtatgcg ctatgccggc
     6481 gactagcgcg gcgtccgtgg ttgggcgaat cggtagccat tcggcgtgtt cggtaatcac
     6541 cgaatcggta tagcgcggat cgataataat gactcgggct ttcgaggtct ccagcgcccg
     6601 gcgcagctct tcaacctgac cgccgccgga catccgcgtt tctgagagat tcaggccaaa
     6661 tagcaccacc agatcggaat gcgcgatctg cgtaaaatgg ctaccgacat aatcaccgtg
     6721 ggtataaggc gtggcggcgg cgatttgcgc cgtggaatag gtgttgtgat aatttaaata
     6781 accgccggtg agatttagta atcttatcca ggcgggtcta ccctgcgtgt gataatacgc
     6841 gccggattga taattataat aaatagcttc ccggccatat ttttcgctaa cgcgcgttaa
     6901 ttccgccgca ataaaggctg tggcctcatc ccatgaaata cgtttaaatt ttccttcgcc
     6961 gcgttttccc actcttttca tcggatactt aatgcgatcc gggctataaa cgcgccagcg
     7021 actggaacgc ccgcgcaggc agggacgaat ctgatgctcg ccgaataccg cgtcatcttt
     7081 cgcgtcttcc ggttcaatac gcacaatgcg atcatttttc acgataacct taagcgggca
     7141 tcggctgcca cagttgacca gacaggcgct gtgcctgacg gtttcgccgt tggcatcctt
     7201 cggtatcggg gtatcctgcg cctgggcagt ggtagcaaaa ggcagcgtaa tcgcctgact
     7261 tagcgtcacc gccgccccta cttttgcagt a
//
LOCUS       DAJVBX010000212         7269 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.212, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000212 DAJVBX010000000
VERSION     DAJVBX010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 7269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7269
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.212"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            618..2252
                     /locus_tag="OPV72_003914"
     CDS             618..2252
                     /locus_tag="OPV72_003914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCR9916085.1"
                     /translation="MLRREKQKQRIIWDKLMIKGKLALVTCALTLVFTSSLFAASDTA
                     DGRTLKLAIGPEPTEGFDPMLGWSHGSYLLLHAPLLKQNADMSWGDLLTEKVDTSPDG
                     KIWTLTLKPGLKFSDGSPLTAEDVVFTYNKAAKSGGKIDMGNFSHARALDARRIEMTL
                     SHPQSTFVNVLGSLGIVPASRYDEKTFAREPIGAGPYRLVSFQPGQQLIVEANPWYAG
                     KKNDFNRLVFVFLDEDNAYAAARSGQLGLVRIAPSMAVTPQQDNLKLWVRDSVENRGI
                     VFPMVPAGKKDANGYPVGNDVTADVAIRRAINYAINRKQLAEQVMEGHAIPAYSAVQG
                     LPWQNPSVVFSDGDIAKARAILEEAGWKINSAGVREKAGKEARLTLWYASGDSTRRDL
                     AEAVRAMLQRLGIVVSLQSGSWETVERHMHANPTLFGWGSLDPMELFHHYSGKAAGVE
                     YYNPGYYSNPAVEAHLKQAIDAPDWQKAIPFWQQVEWDGKQGAGVQGDAAWAWLLNIQ
                     HTYLANPCIDLGKGSPEIHGSWSVLNNLDDWTWTCR"
     gene            2252..3226
                     /locus_tag="OPV72_003915"
     CDS             2252..3226
                     /locus_tag="OPV72_003915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR9916086.1"
                     /translation="MKLFFSHFLRLIILLVLVAAGTFILLSFSPVDPIRAYIGNDLLH
                     VPPEQYARIAARWGLDQPLWERFGHWFWRLLQGDMGYSMLFNMPVASVIRERFATSFA
                     LLAGAWLLSGVLGVTLGFLAGRFLHRWPDKMICRISYLLSSLPTFWIAMLLLALFAVR
                     WPVLPVCCAWDPGNNAGTALLSERLRHLVLPVCALSLLGMGQIALHTREKIASVMKSE
                     FIRFARAQGDKGWSLLRHQVLRHAITPALCLQFASLGELMGGALLAEKVFAYPGLGQA
                     TIDAGLRGDVPLLMGIVLFCTLLVFAGNTISAWLVVVLNRSLERPDAL"
     gene            3216..4028
                     /locus_tag="OPV72_003916"
     CDS             3216..4028
                     /locus_tag="OPV72_003916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR9916087.1"
                     /translation="MLYNPAPTLFRLLLSVTCLLFIAGYGYATLSQPPEVNLLARHLS
                     PDIQHWFGTDNLGRDVWLRCFQGAFTSLQIGVGAALCSGVIALVMAAVARIHPRLDLL
                     VRLITDAMLAMPHLLLLILICFTLGGGKSGVIAAVALTHWPRLALILRADAERVAQSD
                     YLTLTYRLGHGHLYCWRYHYFPALLPQWLTGTLLMFPHAVLHSAALSFLGFGLAPHEP
                     SLGLLLADALRFISHGNWWLVLFPGLMLFTLVMLFDQFARAIQRLWLRSDVC"
     gene            4022..4819
                     /locus_tag="OPV72_003917"
     CDS             4022..4819
                     /locus_tag="OPV72_003917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCR9916088.1"
                     /translation="MLSLQRVTLESARYRWYGARRWSPLLQNVSFDIAPGEMVALVGG
                     SGEGKSLLLQCLLDLLPENLRFRGEITLDGNRLDRHTIRQLRGNTFSYVPQGVQALNP
                     MLNIRKHLNRACHLTGRAWDETQMVQLLQQSDLAPTVLERFPRQLSGGMAKRILACHA
                     SLSQARYILADEITAWLDTALANQLLEHLRGLCERGCGVLWVTHDLLLAARYADRIVA
                     LHQGYITDNIRCERLQPEEMSEPLKRQWQALPELNPLFMPTGEGIEC"
     gene            4813..5403
                     /locus_tag="OPV72_003918"
     CDS             4813..5403
                     /locus_tag="OPV72_003918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCR9916089.1"
                     /translation="MLSCRDLVIRQGGKVLWQNLTFTISAGERVGIHAPSGTGKTTLG
                     RVLAGWQKPTTGDVLLDGSPLPLHQYCPVQLVPQHPELTFNPWRSAGDAVRDAWQPDP
                     ETLRRLYVQPEWLTRRPMQLSGGELARIAILRALDPRARFLIADEMTAQLDPSIQKAI
                     WVYVLEVCRSRSLGMLVINHQSALLDQVCTRHLQVE"
     gene            complement(5485..6618)
                     /locus_tag="OPV72_003919"
     CDS             complement(5485..6618)
                     /locus_tag="OPV72_003919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HCR9916090.1"
                     /translation="MEYLARLNIVAMLMSTTFWINLAVVFFVTLITYWLINWLLNVVY
                     KALQRPDKKDDAHGRLRPIVFEMLKKTSKMLIFFAAFLFSLRFVALPDRLFSTLSHAW
                     FLVVAIQMAIWLDQGVQSWMRHLLYAPGSNKNPVTLVILGMILRVLVWSMMLLSILAN
                     VGVDITALVASLGVGGIAIALAVQTVLSDVFASLSIGFDKPFEIGDFVVFNDVAGTIE
                     HIGLKTTRIRSLSGEQIVCANAQLLQQTIHNYKRMQTRRIVFTFGVATATPPEKLRLI
                     GDMVKKIITDVGETQFDRAHLLAFGQDRLTYEVVHIVNTADYNKYMDIQQEINIRIIE
                     KLIENDIELALPSLVVRAPVQVEETRDYSNTADAKNADKRVMQ"
     gene            6812..7138
                     /locus_tag="OPV72_003920"
     CDS             6812..7138
                     /locus_tag="OPV72_003920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="four-helix bundle copper-binding protein"
                     /protein_id="HCR9916091.1"
                     /translation="MQQEHRECIEQCYECAAACDICASSCLREDNVEMMKHCIELDMQ
                     CAAICRLAAQFMALESEYSQKLCRLCADICKACAEECARHDHDHCQNCARACSQCADA
                     CLKMAA"
     gene            7147..7223
                     /locus_tag="OPV72_003921"
     tRNA            7147..7223
                     /locus_tag="OPV72_003921"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7181..7183,aa:Arg,seq:tct)
BASE COUNT         1616 a         1779 c         2040 g         1834 t
ORIGIN      
        1 cgatattact ctttgcaccc tcctgttgat gtcgtacctg atggacaaat atccgttgaa
       61 gccggatata ttccccatgc cgtgttttta taacttgcgc atcctgtcag caatgagaac
      121 agtacggcta aaaaaatcat cacgagccct ggcggcgtta acatttttcg gttggactcc
      181 atagcatgtc atttcatcgg gttgccatat gactggcgtt ctgctggtaa gtttcattaa
      241 cgcctggttc gtttaatatt ggtttaggtt taaagccagg aagcgctaat tacgatacct
      301 tcttacgttt cagtactgac taataacgtt gagaaaatga acagcgtcgg atgggaagac
      361 gtaatacaga atagaaagga aataagagaa taagatggcg ttaattaacc cggtattcct
      421 ggcgtcattt cccttgcgtt ttatccccgt caaaagtggc ctttagccca cgttggcgct
      481 cccgacgttg acaaccagtg agtgtccata gtgtgcgtat gatgttttta aaagatcgtc
      541 atactttctg ttctgcatca attttttcat tacaaatgct cgccataatg ccgtcctcag
      601 gaggtctccc gacgtttatg ctgcgccggg agaaacaaaa acaacgcata atctgggaca
      661 aattgatgat taaaggcaaa ctggcgctcg tgacgtgcgc gctgactctg gtattcactt
      721 cgtcgctttt cgccgcgtcg gacacggcag atggtcgtac cctgaagctg gccattggcc
      781 ctgagccaac ggaaggcttt gatcccatgc tgggctggag ccacggcagc tacttattgc
      841 ttcatgcgcc gttgcttaag caaaacgccg atatgagttg gggtgattta ctgacggaaa
      901 aagtggatac cagccccgac ggtaaaatct ggacgctaac cttaaagccc gggctgaaat
      961 tctccgatgg ctcgccatta actgccgaag atgtcgtttt tacatacaat aaagcggcga
     1021 agagcggcgg taaaattgac atgggcaatt ttagccatgc gcgagcgctg gatgcgcgcc
     1081 gaattgagat gacgctgagc catccgcaga gcacctttgt gaatgtactc gggtcgttag
     1141 ggattgttcc ggccagccgt tatgatgaaa aaacgttcgc ccgcgaaccg ataggcgccg
     1201 gtccataccg actggtcagc tttcagccgg gtcagcaact gatcgttgaa gctaatccct
     1261 ggtatgcggg taaaaagaat gactttaacc ggctggtttt tgtctttctg gatgaagata
     1321 atgcttatgc cgccgcgcgc agcggacagt tgggactggt gcgcattgcc ccttctatgg
     1381 cggtgacccc gcagcaggat aatcttaaac tctgggtacg cgatagcgtt gaaaaccggg
     1441 gcattgtctt cccgatggtg cctgccggta aaaaggatgc taacggttat cctgtcggca
     1501 acgatgtgac cgctgatgtc gctatcagac gcgcaattaa ctatgccatt aatcgtaagc
     1561 aactggcgga acaggtgatg gaaggccatg cgatacccgc ctatagcgcg gtgcagggat
     1621 taccgtggca aaatccttca gtggtattca gcgatggcga tattgcaaaa gcgcgcgcca
     1681 tcctggaaga ggctggctgg aagataaaca gtgcgggcgt gcgtgaaaaa gcaggtaaag
     1741 aagcgcgtct gaccttatgg tatgccagtg gcgacagcac ccgacgggat ctggccgagg
     1801 cggtgcgcgc catgttgcag cgtttaggca ttgtcgtctc gttgcaatcg ggaagctggg
     1861 aaactgtaga gcgccatatg cacgctaacc ctacgctgtt tggctgggga agtctggacc
     1921 cgatggaact cttccatcac tacagtggga aagccgctgg tgtggaatat tataacccgg
     1981 gctattacag caaccctgcg gtagaagcac atctgaagca ggctatagat gcgcctgact
     2041 ggcaaaaggc gatccctttc tggcagcagg ttgagtggga tgggaagcag ggcgcgggcg
     2101 tccagggcga tgcggcatgg gcatggctgc ttaatattca gcatacttat ctggccaacc
     2161 cctgtattga tctgggaaaa ggctcgccag aaatccacgg tagctggtcg gtgttaaaca
     2221 atcttgatga ctggacctgg acctgtcggt gatgaaattg ttcttcagtc attttttgcg
     2281 gctgattatt ctgttggtgc tggtggctgc cggcaccttc attttgctta gcttttcgcc
     2341 cgttgatcct atccgtgctt atattggcaa cgatctgctc catgttccgc cagaacaata
     2401 tgcgcggatt gcggcgcgct gggggcttga ccagccgctg tgggagcgtt tcggtcactg
     2461 gttttggcgt ctgctccagg gcgacatggg gtattccatg ctgttcaaca tgcctgtcgc
     2521 cagcgtgatc cgggaacgtt ttgcgacgtc attcgcgctg ctggcaggcg cctggctatt
     2581 gtctggtgtg ctgggcgtaa cattgggttt tctggccgga cgttttctcc accgttggcc
     2641 ggataagatg atttgccgta tcagctactt attgtcatcg ttgcccactt tctggatagc
     2701 aatgctgttg ctggcgctgt ttgccgtccg ctggccggta ttacctgttt gttgcgcctg
     2761 ggaccccgga aataatgcag gaacagctct tttatcggaa cgtttacgcc atcttgtgtt
     2821 gccggtatgt gcgttaagtc tgttgggcat ggggcaaatt gcgctgcata cgcgagaaaa
     2881 aatagccagc gtaatgaaga gcgaatttat tcgttttgcg cgcgctcagg gggataaagg
     2941 atggtcgctg ttacgtcacc aggtgttacg tcatgcgatt accccagcgc tctgcttaca
     3001 gtttgcttct ctgggtgaac tgatgggggg agcgttactg gcagaaaaag tctttgcgta
     3061 tccggggctg ggacaggcca ctatcgatgc cggcctgcgt ggcgatgtcc cgctactcat
     3121 ggggatcgtt ttattctgta cgctattagt gtttgccgga aatacgattt cagcctggct
     3181 tgtggtggtg cttaatcgat cgctggagcg tcccgatgct ctataatcct gccccgacgt
     3241 tgtttcgtct gctcctctcc gttacctgtc tgctgtttat tgccggatac ggttatgcca
     3301 cgttgagcca gccgccagag gttaatctgc ttgcccggca tctgtcgcct gatatccagc
     3361 actggtttgg caccgataat ctggggcgcg atgtatggct tcgttgcttt cagggggcct
     3421 tcaccagttt acaaattggc gttggcgccg cgctgtgcag cggcgttatc gcgttagtga
     3481 tggcggcagt ggcgcgcatt catccccggc tggacctcct ggtgcggctg ataaccgatg
     3541 ctatgctcgc catgccgcat ttacttttgc tgatccttat ctgttttacg ctcggcggcg
     3601 gtaaaagcgg cgtcattgcg gccgtggcgt taacgcactg gccccgtctg gcgctgattc
     3661 tgcgcgccga cgcggagcgg gtagcgcaga gtgactacct gacattgacc tatcgtctgg
     3721 ggcatggaca cctttattgc tggcgatatc actattttcc ggcgctattg ccgcaatggt
     3781 tgacgggaac gttattgatg tttcctcatg cggtattgca cagcgcggcg ttaagttttc
     3841 tggggtttgg gctggcgccg catgagcctt cgctggggct gttgctggcg gatgcgttac
     3901 ggtttattag ccatggaaac tggtggctgg tgctatttcc cggcctaatg ttattcacgc
     3961 tggtgatgct cttcgatcag tttgcgcgcg ccattcagcg gctgtggcta aggagtgacg
     4021 tatgctgagt ttacaacggg ttacgctgga aagcgcgcgt tatcgctggt atggcgcgag
     4081 acgctggtcg ccgttattac agaatgtctc ttttgatatc gcgcccggcg aaatggtggc
     4141 attggttggc ggcagcgggg agggaaaaag tctgctgctg caatgcctgc tcgatctgct
     4201 gccggaaaac ttacgttttc ggggtgagat tacgcttgat ggcaaccggc tggacagaca
     4261 taccatcagg cagcttaggg gcaatacgtt tagctacgtg ccgcaggggg tacaggcgct
     4321 taatcctatg ctgaatatca gaaaacattt gaacagagca tgtcatctga ccggacgcgc
     4381 ctgggatgag acgcagatgg tacagttatt acagcaaagc gatcttgcac cgacagtcct
     4441 ggaacgcttt ccccgccagc tctccggtgg gatggctaaa cgaattctgg cgtgccacgc
     4501 ctcgctcagc caggcacgtt atatcctcgc ggatgagatc accgcctggc ttgatacggc
     4561 actggcaaac cagttgcttg agcacttgcg aggtctctgc gagcggggat gcggcgtgct
     4621 gtgggtgact catgacctgc tgctggcggc gcggtatgcc gatcgcattg tggcgctgca
     4681 tcagggttat atcacggaca atattcgctg tgaacgatta cagccggaag agatgagtga
     4741 gccgttaaaa cggcaatggc aggcattgcc tgaactaaac ccgttattta tgccgaccgg
     4801 agagggaata gaatgctgag ctgccgcgac ctcgttattc gtcagggcgg gaaagtctta
     4861 tggcagaacc tgacgtttac gatttctgcc ggtgaacggg taggaattca tgcgccaagc
     4921 ggaacgggga aaacaacgtt ggggcgcgtc ctggccggat ggcaaaagcc gacgacgggc
     4981 gacgttctgc tggacggcag cccgttaccc ctgcatcagt attgcccggt acagctggtc
     5041 ccccagcatc ctgaactgac gtttaatccc tggcgaagcg ccggagacgc tgtgcgtgat
     5101 gcctggcagc ctgacccgga aacgttgaga cgtttgtatg tgcagcccga gtggctgacg
     5161 cgtcggccaa tgcagctctc aggcggggag ttggcgcgta ttgcgatact acgcgcgctt
     5221 gacccgcgag cgcgttttct gattgccgac gaaatgacgg cgcaactcga tccgtctatt
     5281 caaaaagcga tatgggtata cgtgcttgag gtgtgccgca gccgttcatt agggatgttg
     5341 gtgattaatc atcagtctgc gctacttgat caagtctgta cccgccattt acaggtggaa
     5401 tagccgcaag tcgtttctcc gcattgtcgt gtcgccgtta acgcaccggg agcccatggg
     5461 ttcccggtat tgtcggcaga gattttactg catgacgcgt ttatctgcgt tttttgcatc
     5521 agcggtatta ctgtagtccc tggtctcttc aacctgtaca ggggctctga cgaccagact
     5581 tggcagcgcc agttcgatat cattctcaat gagtttttca ataatacgga tatttatctc
     5641 ttgctgaata tccatgtatt tattgtaatc cgcggtattg acgatatgta ccacctcata
     5701 ggtcagccga tcctgaccaa aggccagtag atgggcgcgg tcgaattgtg tttcgccgac
     5761 atcggtaata atctttttca ccatatcgcc gatgaggcgt aacttttccg gcggtgtcgc
     5821 agtggcaacg ccaaaagtaa acacgatacg acgcgtttgc atccgcttat agttgtgtat
     5881 ggtttgctgc aacaactgcg cgttcgcaca aacgatctgt tcgccgctga ggctacggat
     5941 gcgagtggtt ttcaaaccga tatgttcaat cgtaccggct acatcattaa agacgacgaa
     6001 atcgccgatc tcgaagggct tatcgaaacc aatcgacagc gaagcgaaga catcgctcag
     6061 aacggtttgt accgccaggg caatagcaat accgcccacg ccgaggctgg ctaccagtgc
     6121 ggtaatatcc acgccgacgt tcgccaggat ggagagcaac atcatagacc agacgagcac
     6181 gcgcaaaatc ataccaagaa tgactaacgt caccgggttt ttattggagc ctggggcata
     6241 cagtaaatga cgcatccatg actgtacgcc ctgatcaagc caaatcgcca tttgaatcgc
     6301 aaccactaaa aaccaggcgt gagagagggt agagaataac cggtcgggca gggcgacaaa
     6361 gcgcaggcta aagagaaatg cggcaaaaaa gatgagcatc ttactggtct ttttcagcat
     6421 ctcgaaaaca ataggccgca gccgcccatg agcatcatcc tttttatccg ggcgttgtag
     6481 cgctttatag accacattaa gtagccagtt gatgagccag taagtaatga gggtgacgaa
     6541 aaaaacgacc gccagattga tccagaacgt cgttgacatc agcatcgcaa cgatatttag
     6601 tcgtgctaaa tactccattt tacctccgat gaaaagcaga tgaacattac agtatagacg
     6661 tcacatcacg gaggccgatt tccggcttta ctattgctgt tttattcagc acttttgttc
     6721 aaaaagcatg aaaaagaggg gtagccgttt ggctatcccg gcgtttctgt gcagacttat
     6781 ctactcctct taataaaata aggagtcatt tatgcaacaa gaacatcgag agtgtattga
     6841 gcagtgttat gaatgcgcgg cggcgtgtga tatctgcgcc tcttcttgtc tgcgtgaaga
     6901 taacgtcgaa atgatgaagc attgcatcga gttagatatg caatgtgcgg ccatttgtcg
     6961 cctggcggcg caatttatgg cattggaaag cgagtactca caaaaattat gccgcctgtg
     7021 cgcggatatc tgcaaagcct gcgccgaaga gtgtgcaagg cacgatcacg accattgcca
     7081 gaattgcgcg cgggcatgca gccaatgcgc agacgcctgc cttaaaatgg ccgcgtaatt
     7141 tttcttccgc cattagctca accggataga gcatagagct tctacctcta aggttcgggg
     7201 ttcaattcct cgatggcgga ccagttgata tcaaaaaagg ccacctgcgc ggtggccgct
     7261 gagtttctg
//
LOCUS       DAJVBX010000213         7238 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.213, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000213 DAJVBX010000000
VERSION     DAJVBX010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 7238)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7238)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7238
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.213"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(58..285)
                     /locus_tag="OPV72_003922"
     CDS             complement(58..285)
                     /locus_tag="OPV72_003922"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916092.1"
                     /translation="MVIPEVLIGGINVIVDHTNYTNLRRDAQVFFVSPEPVTVTDNLH
                     NSLHFRLFLCVFGLAMQTREAHNQDPRGIDW"
     gene            493..1521
                     /gene="galR"
                     /locus_tag="OPV72_003923"
     CDS             493..1521
                     /gene="galR"
                     /locus_tag="OPV72_003923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator GalR"
                     /protein_id="HCR9916093.1"
                     /translation="MATIKDVARLAGVSVATVSRVINDSPKASEASRLAVTSAMESLS
                     YHPNANARALAQQATETLGLVVGDVSDPFFGAMVKAVEQVAYHTGNFLLIGNGYHNEQ
                     KERQAIEQLIRHRCAALVVHAKMIPDADLASLMKQIPGMVLINRILPGLEHRCVALDD
                     RYGAWLATRHLIQQGHTRIGYICSNHTISDAEDRLRGYYDALAESHIPANDRLVTFGE
                     PDESGGEQAMTELLGRGRHFTAVACYNDSMAAGAMGVLNDNGVGVPGEVSLIGFDDVL
                     VSRYVRPRLTTIRYPIVTMATQAAELALALAGKCPTPEVTHVFSPTLVRRHSVSTPTD
                     TGHLSTTD"
     gene            1532..2554
                     /locus_tag="OPV72_003924"
     CDS             1532..2554
                     /locus_tag="OPV72_003924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000968342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCR9916094.1"
                     /translation="MMATMLDVSRHAGVSKATVSRVLNGTGQVKESTRQKVFTAMQAL
                     DYRPNLLARSLANRTSNSIGLVVSTFDGFYFGSLLRRASRQAEFHNKQLIVTDGHDTP
                     EREQKAVQMLADRQCDAIILYTRYMDEPTILSLIDATEMPLVIINRNITQAHDRAIFF
                     EQETAAFQAVEYLITQGHRDIACITLPVHTPTGTSRVAGYRKALEKYGIPWQPAKVKY
                     GDYTLTRGYDACRELLEEGVTFSALFACNDDTALGAAKALRQAGLRIPQDVSLFGFDD
                     APGATWLEPGLSTVYLPIEDMIATAIDQAVRLANSEPVAPIPPFTGTLILRESVAAGP
                     FFQRPV"
     gene            complement(2564..3826)
                     /gene="lysA"
                     /locus_tag="OPV72_003925"
     CDS             complement(2564..3826)
                     /gene="lysA"
                     /locus_tag="OPV72_003925"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HCR9916095.1"
                     /translation="MSLPHYHAETDLNAENLLRLPAEFGCPVWVYDAHIIRRQIAALQ
                     QFDVVRFAQKACSNIHILRLMRAQGVKVDSVSLGEIERALAAGYDPQTCPDDIVFTAD
                     VIDAATLARVSELHIPVNAGSVDMLTQLGQVSPGHRVWLRVNPGFGHGHSQKTNTGGE
                     NSKHGIWHSDLPAALAVMQKYRLKLVGIHMHIGSGVDYGHLEQVCGAMVRQVLECGQD
                     VEAISAGGGLSIPYHEGEEPVDTRHYYGLWNAAREQIARHLGHAVKLEIEPGRYLVAQ
                     SGVLVTQVRSVKQMGSRHFVLVDAGFNDLMRPAMYGSYHRISALAADGRALENGPWVE
                     TVVAGPLCESGDVFTQQEGGMVETRALPAVIPGDYLVLHDTGAYGASMSSNYNSRPLL
                     PEVLFDNGQARLIRRRQTIEELLALEML"
     gene            3944..4879
                     /locus_tag="OPV72_003926"
     CDS             3944..4879
                     /locus_tag="OPV72_003926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCR9916096.1"
                     /translation="MAAVNLRHIEIFHAVMTAGNLTEAARLLHTSQPTVSRELARFEK
                     VLGLTLFERTRGRLHPTVQGLRLFEEVQRSWYGLDRIVSAAESLREFRQGELSIACLP
                     VFSQSFLPPLLPPFLARYPDVSLNIVPQESPLLEEWLSAQRHDLGLTETLHAPAGTTR
                     TELLTLNEVCVLPCDHPLAAKTVLTPDDFQGENFISLSRLDSYRQLLDTLFAEHQVKR
                     RMVVETHSAASVCAMVRAGAGVSIVNPLTALDYAASGVTVRRFSIDVPFTVSLIRPLH
                     RPASALVDAFSKHLQTHLSRLVEPLEVILGPMTKA"
     gene            complement(4851..5558)
                     /locus_tag="OPV72_003927"
     CDS             complement(4851..5558)
                     /locus_tag="OPV72_003927"
                     /EC_number="5.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate/glutamate racemase"
                     /protein_id="HCR9916097.1"
                     /translation="MKTIGLLGGMSWESTIPYYRLINEGIKQQLGGLHSASLLLHSVD
                     FHDIEVCQRRGEWDKAGDILAQAAQGLQQAGAEGIVLCTNTMHKIAHIIESRCSLPFL
                     HIADATGRAIARQGLHRVALLGTRYTMEQDFYRGRLEQQFAIETIVPEADDRARINQV
                     IFDELCQGIFTDASRHYYLQVIEQLAAQGAQGVIFGCTEIGLLVPQTQSALPVFDTTA
                     IHAADAVSFMLSSSAPE"
     gene            complement(5671..7086)
                     /gene="araE"
                     /locus_tag="OPV72_003928"
     CDS             complement(5671..7086)
                     /gene="araE"
                     /locus_tag="OPV72_003928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose-proton symporter AraE"
                     /protein_id="HCR9916098.1"
                     /translation="MVSINDSALTPRSLRDTRRMNMFVSVSAAVAGLLFGLDIGVIAG
                     ALPFITDHFVLTSRLQEWVVSSMMLGAAIGALFNGWLSFRLGRKYSLMAGAILFVLGS
                     LGSAFASSVEVLIGARVILGVAVGIASYTAPLYLSEMASENVRGKMISMYQLMVTLGI
                     VLAFLSDTAFSYSGNWRAMLGVLALPAVLLIILVVFLPNSPRWLAQKGRHIEAEEVLR
                     MLRDTSEKARDELNEIRESLKLKQGGWALFKANRNVRRAVFLGMLLQAMQQFTGMNII
                     MYYAPRIFKMAGFTTTEQQMIATLVVGLTFMFATFIAVFTVDKAGRKPALKIGFSVMA
                     LGTLVLGYCLMQFDNGTASSGLSWLSVGMTMMCIAGYAMSAAPVVWILCSEIQPLKCR
                     DFGITCSTTTNWVSNMIIGATFLTLLDSIGAAGTFWLYTALNIAFIGITFWLIPETKN
                     VTLEHIERKLMAGEKLRNIGV"
BASE COUNT         1711 a         2050 c         1892 g         1585 t
ORIGIN      
        1 ctgcgcatcc gcgcaggttg gtgcaagaga caggtacgaa gagcgtaccg aataatctca
       61 ccaatcaata cctctgggat cttgattgtg ggcttcgcgc gtctgcatcg ccagtccgaa
      121 aacgcaaagg aataaacgga aatgcaacga gttgtgtaaa ttatccgtta ctgttacagg
      181 ttcaggcgaa acaaaaaaaa cctgcgcatc tctacgcagg ttggtgtaat tcgtgtgatc
      241 aacaatgacg ttgattccac ctatcaatac ctctgggatc accactctat caacctgact
      301 cgctggcctg ccagcagaca atcgcaacag cgcttcgcaa actgtaacga aagatttgta
      361 ttgtcacttt acagacgcat ttctcccgtg caggtcacat ttgtccgaca cggcggggca
      421 agaggcttga acagacgttc attttccgta aaactggcgt aatgtaagcg tttacccact
      481 ataggtatta tcatggcgac cataaaagat gtagcccgac tggccggtgt ttcagtcgcc
      541 accgtttctc gcgttattaa cgattcgcca aaagccagcg aagcgtcccg gctggcggtg
      601 accagcgcaa tggagtccct gagctatcac cctaacgcca acgcgcgcgc gctggcacag
      661 caggcaacgg aaaccctcgg tctggtggtc ggcgacgttt ccgatccttt tttcggcgcg
      721 atggtgaaag ccgttgaaca ggtggcgtat cacaccggca attttttact gattggcaac
      781 gggtatcata acgaacaaaa agagcgtcag gctattgaac agttgattcg tcatcgttgc
      841 gcagcgttag tggtacacgc caaaatgatt ccggatgcgg acctggcctc attaatgaag
      901 caaatccccg gcatggtgct gattaaccgc attttaccgg ggttagaaca tcgctgtgtc
      961 gcgctggatg accgttacgg ggcatggctg gcgacccggc atctgatcca gcaaggtcat
     1021 acgcgtattg ggtatatctg ttccaatcac actatctctg atgccgaaga tcgcctgagg
     1081 ggctattacg atgcgctggc ggaaagccat atcccggcta acgatcggct ggtgacgttc
     1141 ggcgaaccgg atgaaagcgg cggcgagcag gcgatgactg agttattagg tcgcggcaga
     1201 cattttaccg cggtggcctg ctataacgac tcgatggcgg ccggcgcgat gggagtatta
     1261 aatgataatg gcgtgggggt gccgggcgaa gtatcgctca tcggttttga tgatgtactg
     1321 gtctcacgct atgtgcgtcc ccgactgacc accattcggt atccgatcgt caccatggcg
     1381 acacaggcgg cggagctggc cttagcgctg gcagggaaat gccctacgcc agaagtaact
     1441 catgtattta gtccgacact ggtacgccga cattcggtgt ccacgccgac ggataccggg
     1501 cacctgtcga caaccgatta atcagggtag catgatggcg acaatgctgg atgtttcccg
     1561 ccatgcgggc gtatcaaagg ccaccgtctc acgagtgctg aatgggacgg ggcaggtaaa
     1621 agaaagcacg cgccagaaag tgtttacggc gatgcaggct ctggactatc gccccaacct
     1681 gctggcacgc tcgctggcaa atcgcaccag caacagcatc ggtctggtcg tctctacgtt
     1741 tgacggcttc tattttggca gtttgttgcg ccgggcgtcg cgccaggcgg agtttcataa
     1801 caagcagttg atcgtcaccg atggtcacga tacgccggaa cgagagcaga aagccgtaca
     1861 aatgttggcc gacagacagt gcgacgctat tattctttac actcgctata tggatgagcc
     1921 gacgattttg tcgttgattg acgccacgga aatgccgctg gtgattatta atcgcaacat
     1981 cactcaggcc cacgatcgcg ctattttctt cgagcaggag acggcggcat tccaggcggt
     2041 ggaatacctg attacgcagg gccatcgcga tatcgcctgt attacgctgc ctgttcatac
     2101 tcccaccggc acatcacgcg tagcgggtta tcgaaaggcg ctggaaaaat atggcattcc
     2161 ctggcaaccg gcaaaagtga aatacggcga ttacacgctg acgcgcggct atgacgcctg
     2221 ccgggaatta ctggaggaag gcgtcacgtt tagcgcgcta ttcgcctgta atgatgacac
     2281 ggcgctgggc gcggcaaaag cgctgcgcca ggccggatta cgcatcccgc aggatgtgtc
     2341 gctgtttggt tttgacgatg cgccgggcgc aacctggctt gagccggggc tttcaacagt
     2401 ctatttaccc atcgaggata tgatagccac cgcaattgat caggccgttc gtctggcgaa
     2461 cagcgagccg gtcgccccga tcccgccctt taccggcacg ctgattctgc gcgagtccgt
     2521 cgccgcgggc ccgttttttc aacgtccggt ctaatgatgc gcttcagagc atctccagcg
     2581 ctaacagctc ttcaatggtt tgacgacggc ggatcagccg cgcctgtcca ttgtcaaaca
     2641 gtacttccgg caggagcggg cggctgttgt aattcgatga catagacgcg ccgtacgcgc
     2701 cggtatcgtg caatacgagg taatcgccgg ggatgaccgc aggtaaggcg cgtgtttcaa
     2761 ccattccccc ttcctgctgc gtaaaaacat cgcctgattc gcatagcggc ccggcgacca
     2821 ccgtctcgac ccacgggcca ttttcaagcg cgcgaccatc cgccgccagc gccgaaatac
     2881 ggtgatagct accgtacatc gccgggcgca tcagatcgtt aaaaccagcg tcgaccagca
     2941 cgaaatggcg gcttcccatc tgttttacgc tacgcacctg cgttaccagc acgcccgatt
     3001 gcgccaccag ataacgtccg ggttcgatct caagtttgac cgcatgtccc agatggcggg
     3061 cgatttgctc gcgcgccgcg ttccacagac catagtaatg gcgcgtatca acgggctctt
     3121 ctccctcatg ataaggtatc gagagtccgc cgcctgccga aatcgcctcc acatcctgac
     3181 cacattccag cacctggcgt accatcgcgc cgcaaacctg ctccagatgg ccataatcga
     3241 cgccggaacc aatgtgcata tggataccga caagtttcag tcggtatttc tgcattaccg
     3301 ccagcgccgc cggaagatcg ctatgccaga tgccgtgttt gctgttttcg cccccggtgt
     3361 tggttttctg gctgtggccg tgaccaaagc caggattcac gcgcaaccag acgcgatgcc
     3421 caggcgaaac ctgaccaagc tgcgtcagca tatctaccga gccggcattg accggaatat
     3481 gcagttcact gacgcgcgcc agcgtggcgg cgtcaatcac atcggcggta aaaacgatat
     3541 catcagggca cgtttgcgga tcgtagcccg ccgccagcgc acgttcgatc tcccccaatg
     3601 aaacagaatc caccttgaca ccctgcgcgc gcattaagcg caggatatga atgttcgaac
     3661 aggctttttg cgcaaaacgc acgacgtcaa actgctgcag ggcggctatc tgacggcgaa
     3721 taatgtgcgc gtcatagacc cagaccggac agccgaattc agcaggcaat ctgagcaaat
     3781 tttcagcgtt aaggtcagtt tcagcgtgat aatgcggcaa tgacataaca aactccggaa
     3841 caggcttttt aacgattacg ccatacctta gaaagaataa aaaatatcgt tttattgtca
     3901 gtctatgcaa aaatgatatg ggataaatga ttcagggaaa cgtatggctg ccgttaattt
     3961 acgtcacatt gaaatttttc atgccgtaat gaccgccgga aatctcaccg aagcggcgcg
     4021 gctgctgcat acctcgcagc ctaccgtcag tcgcgagctg gcgcgttttg agaaagtgct
     4081 gggattaacg ctgtttgagc gcacacgcgg gcgcttacat ccgacggtgc aagggctacg
     4141 cctgttcgaa gaggtacaac gctcctggta tgggttggat cgcatcgtca gcgcggcgga
     4201 aagtctgcgc gagttccgtc agggcgaact ctctatcgcc tgcctgccgg tcttttcaca
     4261 atcctttttg ccgccgctac taccgccttt tttggcgcgt tatccggatg tcagcctgaa
     4321 tattgtgccg caggagtcgc cgttgctgga agagtggctc tccgctcagc gccacgactt
     4381 agggctgacg gagacgcttc atgccccggc aggaacaacc cgcaccgagt tactaacgct
     4441 gaatgaagtg tgcgtactgc cctgcgacca tccgcttgcc gccaaaacgg tactgacgcc
     4501 agacgatttt cagggggaaa actttatcag cctctcccgc ctggacagct atcgacagtt
     4561 gttggatacg ttatttgccg aacatcaggt gaagcgcaga atggtggtgg aaacgcatag
     4621 cgcggcctcc gtctgcgcga tggtgcgcgc cggggcgggc gtttcgatcg ttaacccgct
     4681 gaccgcgctg gactatgccg ccagcggcgt caccgtccgc cgcttcagca ttgacgtgcc
     4741 ctttaccgtc agcctgattc gcccgctaca ccgccccgcc tccgcgctgg ttgacgcctt
     4801 cagtaagcat ttacaaacgc atctttcgcg cctggtcgaa ccgctggagg ttattctggg
     4861 gccgatgacg aaagcataaa gctcacggca tctgcggcat gaattgccgt ggtatcgaaa
     4921 accggtagcg cgctttgcgt ctggggaaca agcaaaccta tttcagtaca gccaaaaata
     4981 acgccctgcg cgccttgcgc agccagttgt tcgataacct gtaaataata gtggcgcgac
     5041 gcgtcagtga atatcccctg acagagctcg tcaaaaatca cctgattgat acgcgcccga
     5101 tcgtccgcct ccggcacgat ggtctcaatc gcaaattgct gttccagccg cccgcgataa
     5161 aaatcctgct ccatcgtata gcgagtccct aatagcgcca cgcgatgcaa cccctgacgg
     5221 gcgatggctc gcccggtagc atccgcgatg tgtaggaaag gcagagaaca acgagattca
     5281 ataatgtgcg cgattttatg catggtgttg gtacacagca caataccttc tgcgcccgcc
     5341 tgctgtaacc cctgcgcggc ctgcgccagg atatcgcccg ctttatccca ttcgccgcgg
     5401 cgttgacata cttcaatatc gtggaaatct acgctatgca gcagtaagct cgccgagtgc
     5461 aggcctccca gctgctgttt aatgccttca ttgattaaac ggtaataagg gatagtcgat
     5521 tcccagctca tcccccccaa cagcccgatc gttttcactg cgctctcctt tttgtaaagc
     5581 attatggcag tgaaacaaac ttacacatcc gtttccagtc tatttttcat catgccggat
     5641 aacaggcgtc atccggcatg ggagggggga ttacacgcca atatttctta gcttctcgcc
     5701 cgccattagc ttgcgttcga tgtgctccag ggtgacattt ttggtttccg gaatcagcca
     5761 gaaagtgatg ccgataaaag cgatattcag cgcggtgtag agccagaatg tacctgccgc
     5821 gccaatgctg tccaacagtg tcaggaatgt cgcgccgatg atcatgttcg atacccagtt
     5881 tgtcgtggtt gaacaggtaa tgccaaaatc acgacatttc agcggctgga tttccgaaca
     5941 cagtatccac accaccggag cggcgctcat cgcgtaaccg gcgatacaca tcatcgtcat
     6001 cccaacggaa agccaggaga gaccgcttga tgccgtaccg ttatcaaact gcatcaggca
     6061 gtagcccaac accaatgtcc ctaacgccat tacgctgaaa ccgattttta acgccggttt
     6121 acgcccggcc ttatcgaccg taaagacggc gataaaagtc gcgaacataa aggtcagtcc
     6181 gaccaccagc gtagcgatca tttgctgttc cgtggtggta aagccggcca ttttaaaaat
     6241 gcgcggcgca tagtacataa tgatgttcat gccggtgaac tgctgcattg cctgtagcaa
     6301 cataccgagg aacacggcgc ggcgaacatt acggttagct ttaaataatg cccatccgcc
     6361 ctgcttgagt ttgaggcttt cccgaatctc attcagttca tcacgggctt tttccgaggt
     6421 atcgcgcagc atacgcagca cctcttccgc ttcgatatgg cgaccttttt gcgccagcca
     6481 gcgcggacta ttcggcagga ataccaccag aataatgagc aacaccgcag gcagcgccag
     6541 cacgcccaac atcgcgcgcc agttgccgct gtagctgaat gccgtatcgg ataaaaaagc
     6601 cagcacaatg cctaacgtca ccatcagttg atacatactg atcattttac cgcgaacatt
     6661 ttcgctagcc atttcagaga gataaagcgg cgcggtatag gacgcaatcc ctactgctac
     6721 gcccagtatc acgcgggcgc caatcaatac ttccacgctg gaagcaaacg ccgaccccag
     6781 cgagccgagc acgaacaaaa tcgcgccagc catcaggcta tacttacgcc ccagccgaaa
     6841 tgaaagccag ccgttaaata atgcgccaat tgccgcgcca agcatcatac tgctgacgac
     6901 ccattcctgc agccggctgg tcagtacgaa atggtcggta ataaaaggca gcgccccagc
     6961 gataacgccg atatccagac caaataacag tcccgctacc gctgcagaaa ccgaaacaaa
     7021 catattcata cgtcgtgtgt cgcgaagcga acgcggcgtt aaagcagagt cattaataga
     7081 gaccatattt tcctgccacc acagagtaag acatagcctg aaagtacggg atactcttcc
     7141 tcaagtgtca ggctggaaac ggcataaata tggattaaat ggctacgcta tagcgatatg
     7201 tgatggatat tacacttttt aaatttaacg ccgttgcc
//
LOCUS       DAJVBX010000214         7185 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.214, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000214 DAJVBX010000000
VERSION     DAJVBX010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 7185)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7185)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7185
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.214"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            107..1156
                     /gene="allD"
                     /locus_tag="OPV72_003929"
     CDS             107..1156
                     /gene="allD"
                     /locus_tag="OPV72_003929"
                     /EC_number="1.1.1.154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ureidoglycolate dehydrogenase"
                     /protein_id="HCR9916099.1"
                     /translation="MKISRETLHQLIENKLYKAGLKREHAAIVADVLVYADARGIHSH
                     GAVRVEYYAERISKGGTNREPTFRIENTGPCTAILHADNAAGQVAAKMGMEHAIEIAK
                     KNGVAVVGISRMGHSGAISYFVRQAAREGLIGLSICQSDPMVVPFGGADIYYGTNPLA
                     FAAPSEGDDIITFDMATTVQAWGKVLDARSRNESIPESWAVDKNGAPTHDPFAVNALL
                     PAAGPKGYGLMMMIDILSGILLGLPFGRQVSSMYEDLHAGRNLGQLHLVINPAFFSSC
                     ELFRKHISQTMQELNSVKPAPGFKQVYYPGQDQDIKQKNADMNGIDIVDDIYQYLISD
                     ALYLKSYETKNPFAQ"
     gene            1178..2413
                     /gene="allC"
                     /locus_tag="OPV72_003930"
     CDS             1178..2413
                     /gene="allC"
                     /locus_tag="OPV72_003930"
                     /EC_number="3.5.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="allantoate deiminase"
                     /protein_id="HCR9916100.1"
                     /translation="MIKHFRHAIEETLPWLSSIGADPTGGMTRLLYSPEWLETQQQFK
                     KRMAESGLETRFDDVGNLYGRLCGTQFPEQVILSGSHIDTVVNGGNLDGQFGALAAWL
                     ALDWLKATYGAPLRTVEVVSMAEEEGSRFPYVFWGSKNIFGLANPEEVRYIQDAKGTG
                     VVDAMQACGFTLPAAPLAARTDIRAFVELHIEQGCVLESNGQSIGVVNAIVGQRRYTV
                     TLNGESNHAGTTPMGYRRDTVHAFSRICSQSIEKAKQHGDPLVLTFGKVEPQPNTVNV
                     VPGKTTFTIDCRHTDAAVLREFTEQLENNMRAICDEMDISIDIDLWMDEAPVPMNAEL
                     VAALTRLCETEQLNYRIMHSGAGHDAQIFAPRVPTCMIFVPSINGISHNPAERTNIND
                     LAEGVKTLALMLHQLAWQK"
     gene            2424..3209
                     /gene="allE"
                     /locus_tag="OPV72_003931"
     CDS             2424..3209
                     /gene="allE"
                     /locus_tag="OPV72_003931"
                     /EC_number="3.5.3.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(S)-ureidoglycine aminohydrolase"
                     /protein_id="HCR9916101.1"
                     /translation="MGYLNNVTGYRDDLLANRAIVKHGNYALLTPDGLVKNIIPGFEN
                     CDVTILSTPKLGASFVDYLVTLHQNGGNQQGFGGEGIETFLYVIAGNIEAKAEGKTFS
                     LTQGGYLYCPPGEMMTFSNAQTEDSQLFLYKRRYTPVEGHAPWLVSGNASQLERIHYE
                     GMEDVILLDFLPKELGFDMNMHILSFEPGASHGYIETHVQEHGAYILSGQGVYNLDNN
                     WVPVKKGDYIFMGAYSLQAGYGVGRGEAFSYIYSKDCNRDVMI"
     gene            complement(3288..4436)
                     /gene="glxK"
                     /locus_tag="OPV72_003932"
     CDS             complement(3288..4436)
                     /gene="glxK"
                     /locus_tag="OPV72_003932"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate 3-kinase"
                     /protein_id="HCR9916102.1"
                     /translation="MKIVIAPDSFKESLSADKCCQAIKAGFSTVFPDARYVCLPIADG
                     GEGTVDAMVAATGGKRVSVDVSGPMGEKVNGFYGLTGDGKTAIIEMAAASGLMLVAPE
                     ARNPLRASSFGTGELIRHALDAGIRHIILGIGGSATVDGGMGVAQALGVRFLDAQGTP
                     LGAEGGNLSRLASIDLQGRDPRISECRIEVACDVDNPLVGPRGAAAVFGPQKGATPEM
                     VETLENGLRNYARILHALTGRDMSQIPGGGAAGGMGIAAIVFLEAEMKPGIEIVMQAV
                     KLEEAVKEASLVITGEGRIDSQTAGGKAPIGVASVAKRHHVPVIGIAGVLGDGVEVVH
                     RHGIDAVFSILPRLAPLPEVLANGEQNLYHSACNIARVIKLGQDIGTR"
     gene            complement(4459..5757)
                     /locus_tag="OPV72_003933"
     CDS             complement(4459..5757)
                     /locus_tag="OPV72_003933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil/xanthine transporter"
                     /protein_id="HCR9916103.1"
                     /translation="MFPVINRESVLSGFQWFFFIFCNTVVVPPTLLSAFHLPADNLLM
                     LTQYAFLTTALACLVQAFCGHRRAIMEGPTGLWWGAILTITLGEASRGTPLNDIASSL
                     SVGIAISAMVTIFIGISGLGHRLARLFTPAVMVFFMLLLGAQLTSIFFKGMLGLPFGI
                     ADTSARIKLAPFGLAVAVMCFILAMIIFLQQRISRYALLVGTVVGWGLWRLCFPSSHL
                     PPGELSWRWFPLGSHGTLMPGIIVTAVMTGLVNISNTYGAIRGTDIFYPHQGSGSSRY
                     RRSFMISGLMTLVTVPFAVVPFSPFVSSIGLLTQTGDSSRKSFICGSALCLLVAIITP
                     LTRLFCAIPLAISSAVMLVSYLPLLYSGLVFSQQITFTARNIYRLALPLFVGIFLMGL
                     PPVYLQDLPLMIRPLLSNGLLVGILLAVLMENLIPWERIK"
     gene            complement(5816..7177)
                     /gene="allB"
                     /locus_tag="OPV72_003934"
     CDS             complement(5816..7177)
                     /gene="allB"
                     /locus_tag="OPV72_003934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="allantoinase AllB"
                     /protein_id="HCR9916104.1"
                     /translation="MSFDLIIKNGTVILENEARVIDIAVQGGKIAAIGENLGEAKNVL
                     DATGLIVSPGMVDAHTHISEPGRTHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDR
                     ETIELKFDAAKGKLTIDAAQLGGLVSYNLDRLHELDEVGVVGFKCFVATCGDRGIDND
                     FRDVNDWQFYKGAQKLGEMDQTVLVHCENALICDELGEEAKREGRVTAHDYVASRPVF
                     TEVEAIRRVLYLAKAAGCRLHVCHISSPEGVEEVTRARQEGQDVTCESCPHYFVLDTD
                     QFEEIGTLAKCSPPIRDQENQKGMWEKLFNGEIDCLVSDHSPCPPEMKAGNIMQAWGG
                     IAGLQNCMDVMFDEAVQKRGMSLPMFGKLMATNAADIFGLKHKGRIAPGKDADLVFIQ
                     PDSSYVLKNEDLEYRHKVSPYVGRTIGARITKTILRGDVIYDIEHGFPVPPKGQFILK
                     HQQ"
BASE COUNT         1820 a         1973 c         1751 g         1641 t
ORIGIN      
        1 taaattctaa ttatattttt ttgcctgtct ggatcacata atcattttat tttcccggta
       61 tgttaatcgc agtcatgctt cacaccgtcg ttaaaaagga agacagatga aaatcagtcg
      121 ggaaacactc catcagctta tcgaaaataa gctttataaa gccggactaa aacgtgagca
      181 cgccgccatc gtcgccgacg tactggttta tgcagatgcc agaggtattc actcacatgg
      241 cgccgtacgc gttgaatatt atgccgaacg aatttcaaaa ggcggcacca accgggagcc
      301 gacgttccgc attgagaata ccggtccctg tacggcgata ctgcatgccg ataatgctgc
      361 cggacaggtc gcagccaaaa tgggaatgga gcatgctatt gaaatagcca aaaaaaatgg
      421 cgtcgcggtt gtcggcatta gcagaatggg ccatagcggc gccatctctt atttcgtccg
      481 ccaggccgct cgcgaaggcc tgattggtct gtctatctgt cagtccgatc ctatggtcgt
      541 gccgtttggc ggggcggata tttactatgg cactaatccg ctggcctttg ccgcgccgag
      601 cgaaggcgat gacatcatta cctttgatat ggccaccacc gtgcaggcct ggggaaaagt
      661 cctcgatgca cggtctcgca atgagtccat tccggagagt tgggccgtcg ataaaaacgg
      721 cgcgccgaca catgatcctt ttgccgtcaa tgcgttatta cccgccgcag gcccgaaagg
      781 ttacggcctg atgatgatga tcgatatttt gtccggcatt ctgctggggc tgccgtttgg
      841 tcgccaggtc agttcgatgt atgaagattt acacgccgga cgcaatttag gacaacttca
      901 tctggtcatt aatccggcgt tcttttcttc ctgtgaatta ttccgcaaac atattagtca
      961 gactatgcag gaactcaatt ccgtgaagcc cgctcccggt tttaaacagg tttattatcc
     1021 tggacaggat caggatatta aacagaaaaa tgccgatatg aatggtatcg atattgttga
     1081 tgatatttat caatatctga tttccgatgc cctctatctc aagtcatacg aaacaaaaaa
     1141 tccctttgcc caataattat tgaaacagga attttctatg ataaagcatt ttcgccacgc
     1201 gatagaagaa acattgccct ggctctcttc cattggagcc gatcctacgg gtggaatgac
     1261 gcgtttactt tattcgcctg agtggctgga aacacagcag caatttaaaa agcgaatggc
     1321 agaaagcggt ctggaaacac gctttgatga cgtcggaaat ttatatggcc gcctttgcgg
     1381 cacacaattt ccggagcagg tgattttaag cggttcgcat attgatacgg tcgtcaacgg
     1441 cggcaatctg gacggacaat tcggcgcgct tgccgcctgg ctggcgctcg actggctaaa
     1501 agcgacctac ggcgcgccgc tgcgcaccgt cgaagtagtg tcaatggcag aggaagaagg
     1561 cagccgtttc ccttacgttt tttggggcag caagaacatt tttggcctgg cgaatcctga
     1621 agaggtacgc tatatccagg acgccaaagg cacaggcgtt gtcgacgcta tgcaggcgtg
     1681 cggatttacc cttcccgccg cgccgctcgc tgcgcgaacc gatatccgcg cctttgttga
     1741 attgcatatt gagcaaggct gcgttctgga gagcaacgga cagtcgattg gcgtcgtcaa
     1801 cgccatcgtc gggcaacgtc gctacacggt gacgctcaac ggcgagtcca accatgcagg
     1861 cacaacgcca atgggctatc gtcgcgatac ggtgcatgcc ttcagtcgta tttgcagtca
     1921 gtccattgaa aaagccaaac agcatggcga tcccctggta ttaacgttcg gcaaagttga
     1981 gccgcagccg aatacggtca atgttgtccc tggaaaaacc acatttacaa tcgattgccg
     2041 gcatacggac gccgcggtac ttcgcgaatt taccgaacag ttggaaaaca atatgcgcgc
     2101 catctgcgat gaaatggata tcagcatcga tatcgatttg tggatggacg aagcgccggt
     2161 gccgatgaac gccgaactgg tcgcggccct caccaggctg tgtgaaaccg aacaactgaa
     2221 ctatcgcata atgcatagcg gcgcaggtca tgacgcgcaa attttcgcgc cgcgcgtccc
     2281 tacctgtatg attttcgtcc ccagcattaa tggtatcagc cataacccgg cggaacgtac
     2341 caacattaat gaccttgctg aaggggtcaa aactctggca ttaatgcttc atcaacttgc
     2401 ctggcaaaaa taaggagcca tcaatgggat atctgaataa cgtcacgggt taccgcgatg
     2461 atttactggc gaaccgcgcc attgtgaaac acggtaacta tgcgctctta acgccggacg
     2521 gtctggtgaa aaatattatt cccggctttg aaaactgtga cgtcaccatc ctttcgacgc
     2581 cgaagctggg tgcttctttc gtcgattacc tggtcacctt acatcagaat ggcggcaacc
     2641 agcagggctt tggcggcgag gggattgaaa cttttctcta tgtcattgcg ggaaatattg
     2701 aagctaaagc agaaggaaaa acattctctt taactcaggg cggctacctc tattgtccac
     2761 cgggggagat gatgaccttt agtaacgctc aaacggaaga cagccagcta tttttatata
     2821 aacgccgcta tactcctgtc gaggggcatg ccccgtggtt ggtttccggc aatgccagcc
     2881 agctggagcg tattcattat gaaggcatgg aagatgttat cctgctggat ttcctgccta
     2941 aagagctggg cttcgatatg aatatgcata ttctgtcgtt cgaaccgggc gccagccacg
     3001 gctatattga aacccacgtc caggaacatg gcgcttatat cctttccggc cagggggttt
     3061 ataacctcga caacaactgg gtgccggtga aaaaaggcga ctacatcttc atgggcgctt
     3121 attccctgca ggccggatac ggtgtaggtc gtggcgaagc attcagctac atctactcca
     3181 aagactgtaa ccgcgacgtt atgatttaac ggcgggcagc cctcctgatt atttttattt
     3241 agctatgttg gattttgcca cggtgagaac cgtggatttt tttatactta acgagtcccg
     3301 atgtcctggc caagtttgat gacgcgggca atattacagg cgctgtggta gagattttgt
     3361 tcaccgttcg ccagaacctc cggcaaaggc gccagccgcg gcaaaatact gaatactgca
     3421 tcaataccgt gacgatggac cacttccacg ccgtcgccca atacgccggc aatgccgata
     3481 accgggacat gatgccgttt cgccactgat gcgacgccta tcggcgcttt tcctcccgcc
     3541 gtttgcgagt cgattcgccc ttctccggta atcaccagcg aggcctcttt taccgcctcc
     3601 tccagcttca ccgcctgcat aacaatctca ataccgggct tcatttccgc ttccaggaag
     3661 acgatagcgg caatccccat tcctccggcc gctccaccgc ccggtatttg agacatgtcg
     3721 cgtccggtca gggcatgtaa aatacgggca taattacgca atccattttc cagcgtctcg
     3781 accatttcag gcgtcgcccc tttctgcgga ccgaataccg ccgccgcgcc gcgtggcccc
     3841 accaacgggt tatcaacatc acaggcgacc tcaatacgac actctgaaat tcgcggatcg
     3901 cgcccctgca ggtcaatgct cgccaggcgc gataaattgc ccccttcggc gccaagcggc
     3961 gttccctgcg cgtccagaaa acgcacaccg agcgcctgcg ctactcccat tccgccatcc
     4021 accgtggcgc tgccgccgat acccagaata atatggcgaa ttcccgcgtc cagggcgtga
     4081 cgaatcaatt cgcctgtgcc gaaactggat gcccgcagcg gattacgcgc ctcgggcgcc
     4141 accagcatca atccgctcgc cgccgccatt tcaataatcg ccgttttgcc gtcgccggtc
     4201 aggccataaa atccgtttac tttttccccc atcggcccgc taacgtccac agaaacccgt
     4261 ttcccgccgg tcgcagccac catcgcatcc acggttcctt ctccaccatc ggcgatcggt
     4321 aaacaaacat agcgcgcatc cggaaatacg gttgaaaatc ccgctttaat agcctgacag
     4381 catttatcag cgcttaagct ctctttaaat gaatctggcg caattacaat cttcattatg
     4441 tctccttgtt ttctcacgtt atttaatgcg ttcccacgga ataagatttt ccataagcac
     4501 tgccagtagg attcccacca gtaatccgtt actaagcaga ggacgaatca tcagtggaag
     4561 atcctgtaaa tagaccggag gaagccccat caaaaaaatg ccgacaaaaa gcggtaacgc
     4621 caggcgataa atattccgcg cggtaaacgt aatttgctgg ctaaaaacca aaccggaata
     4681 aagtaaaggt aaataagaga ccagcataac ggcgctgctg atcgccagtg gaatagcgca
     4741 aaataagcgg gttaacggcg ttataatggc aaccagcaga cacagcgcgc taccgcagat
     4801 aaaggatttg cgagaactgt cgccggtttg cgttaataaa ccaatggaag atacaaaagg
     4861 cgaaaaaggc acgaccgcaa aaggcaccgt cactaacgtc atcagtccgg aaatcataaa
     4921 gcttcggcga taacgagaac tgcccgaccc ttgatgcgga taaaagatat cggtaccgcg
     4981 gatagcgccg taagtgttgc tgatgttgac taaccccgtc atcaccgccg tcacaataat
     5041 acccggcatc agcgtgccgt ggctgcccag cggaaaccat cgccagctta attcacccgg
     5101 cggtaagtgt gacgaaggaa agcataaccg ccatagcccc cacccgacca cggtccctac
     5161 cagtaacgcg taacgggaga tacgctgctg caagaaaata atcatcgcga ggataaaaca
     5221 catcaccgcg accgccagcc caaagggggc caatttgatt ctggcgctgg tatcggcaat
     5281 gccaaaaggc agccccagca tgcctttaaa aaatattgag gtcagctgcg cgcccaaaag
     5341 cagcatgaaa aaaaccatta ccgccggcgt aaacaggcga gccagacggt gtcctaagcc
     5401 gctaatgccg ataaatatcg tcaccatcgc ggagatcgcg atcccgaccg acaggctgga
     5461 ggcgatatcg ttcagcggcg tgccgcgaga cgcctcgcca agcgtaatcg taagtatagc
     5521 gccccaccac aaccctgtcg gcccttccat aatggcgcgg cgatggccgc aaaatgcctg
     5581 aaccaggcag gccaacgcgg tggtcagaaa agcgtattgt gtgagcatta acaggttatc
     5641 agcgggaaga tgaaaagcgg acagcaaggt agggggaacc acaaccgtgt tacagaaaat
     5701 aaagaaaaac cactgaaagc cggacaatac actttcgcgg ttaataacag ggaacatatc
     5761 cacaccttaa aatagagaat gcccgtcgtg acgacgggca ttaaatcaca ccggattact
     5821 gctgatgttt aaggataaac tgaccttttg gcggcacagg gaagccatgc tcgatgtcat
     5881 aaataacatc gccgcgcaaa atcgttttgg taatacgcgc gccaatagta cggccaacat
     5941 acggactgac tttatggcga tattccagat cttcattttt cagaacatag ctgctgtcag
     6001 gctgaataaa gaccaggtca gcatctttgc cgggggcaat acgtccttta tgtttcagac
     6061 caaaaatatc ggcggcgttg gtcgccatta atttgccaaa catcggcaac gacataccgc
     6121 gtttttgcac cgcttcatca aacatgacgt ccatgcagtt ttgcagtccg gcaattccac
     6181 cccatgcttg catgatattg cctgctttca tttccggagg acatggagag tggtcggata
     6241 ccaggcagtc gatttcgccg ttaaacagtt tttcccacat ccctttctgg ttttcctggt
     6301 cgcgaattgg cggagaacat tttgccaggg tgccaatctc ttcgaactga tcggtatcga
     6361 ggacaaaata gtgcgggcac gattcacagg tgacatcctg gccttcctga cgcgcacgcg
     6421 ttacttcctc taccccctcc gggctgctga tatgacaaac gtgcagacgg caacctgccg
     6481 ctttcgccag atacagcacg cgacgaatgg cttccacttc agtaaatacc ggacgtgagg
     6541 cgacataatc atgcgccgtt acgcgacctt cgcgtttagc ttcttcgccc agctcatcgc
     6601 aaatcagagc attttcgcaa tgtaccagta ccgtctggtc catctctccc agtttttgcg
     6661 cgcctttgta aaactgccag tcattaacgt cgcgaaaatc attatcgatg ccacgatcgc
     6721 cgcaggtggc gacaaagcac ttgaagccga caacgcccac ttcgtccagc tcatgcagcc
     6781 gatccaggtt ataagagacc aaaccgccca actgcgcggc gtcgatggtc aatttacctt
     6841 ttgccgcgtc aaacttgagt tcaatcgtct cacgatcgac cgtcgccggc agctgattga
     6901 gcggcatctc aatcatcgtg gtaataccgc ctttcgccgc cgcgcgcgta ccggtttcat
     6961 agccttccca gtgggtacgg cccggttcag aaatgtgggt atgcgcgtca accatgcccg
     7021 gcgaaacgat caatcccgtc gcatccagca cgtttttcgc ttcccccagg ttctcgccaa
     7081 tcgcggcgat ttttccgccc tggacggcga tatcgataac tctcgcttcg ttttctaaga
     7141 tgacagtacc gttcttaata attaaatcaa aagacataac aaact
//
LOCUS       DAJVBX010000215         7014 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.215, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000215 DAJVBX010000000
VERSION     DAJVBX010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 7014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7014
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.215"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(183..1262)
                     /gene="fbaA"
                     /locus_tag="OPV72_003935"
     CDS             complement(183..1262)
                     /gene="fbaA"
                     /locus_tag="OPV72_003935"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016505616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HCR9916105.1"
                     /translation="MSKIFDFVKPGVITGDDVQKVFQVAKENNFALPAVNCVGTDSIN
                     AVLETAAKVKAPVIVQFSNGGASFIAGKGVKTDVPQGAAILGAISGAHHVHQMAEHYG
                     VPVILHTDHCAKKLLPWIDGLLDAGEKHFAATGKPLFSSHMIDLSEESLHENIEICSK
                     YLARMSKIGMTLEIELGCTGGEEDGVDNSHMDASALYTQPEDVDYAYTELSKISPRFT
                     IAASFGNVHGVYKPGNVVLTPTILRDSQDYVSKKHNLPHNSLNFVFHGGSGSTAQEIK
                     DSVSYGVVKMNIDTDTQWATWEGVLNYYKENEAYLQGQLGNPKGEDQPNKKYYDPRVW
                     LRAGQTSMIARLEKAFKELNAIDVL"
     gene            complement(1364..2527)
                     /gene="pgk"
                     /locus_tag="OPV72_003936"
     CDS             complement(1364..2527)
                     /gene="pgk"
                     /locus_tag="OPV72_003936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HCR9916106.1"
                     /translation="MSVIKMTDLDLAGKRVFIRADLNVPVKEGKVTSDARIRASLPTI
                     ELALKQGAKVMVTSHLGRPTEGEYNEEFSLLPVVNYLKDKLSNPVRLVKDYLDGVDVA
                     EGELVVLENVRFNKGEKKDDEALSKKYAALCDVFVMDAFGTAHRAQASTHGIGKFADV
                     ACAGPLLAAELDALGKALKEPARPMVAIVGGSKVSTKLTVLDSLSKIADQLIVGGGIA
                     NTFVAAQGHSVGKSLYEADLVDEAKRLLTTCDIPVPTDVRVATEFSETAPATLKSVND
                     VKEDEQILDIGDASAQQLAEILKNAKTILWNGPVGVFEFPNFRKGTEIVANAIADSEA
                     FSIAGGGDTLAAIDLFGIADKISYISTGGGAFLEFVEGKVLPAVAMLEERAKK"
     gene            complement(2549..3595)
                     /gene="epd"
                     /locus_tag="OPV72_003937"
     CDS             complement(2549..3595)
                     /gene="epd"
                     /locus_tag="OPV72_003937"
                     /EC_number="1.2.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="erythrose-4-phosphate dehydrogenase"
                     /protein_id="HCR9916107.1"
                     /translation="MTVRIAINGFGRIGRNVVRALYESGRRAEITVVAINELADAAGM
                     AHLLKYDTSHGRFAWEVRHEREQLFVGDDVIRILHERTLADLPWRELGVDVVLDCTGV
                     YGNREHGEAHIAAGAKKVLFSHPGSNDLDATVVFGVNQNQLRAEHRIVSNASCTTNCI
                     IPVIKLLDDAYGIESGTVTTIHSAMNDQQVIDAYHSDLRRTRAASQSIIPVDTKLAAG
                     ITRIFPQFNDRFEAIAVRVPTINVTAIDLSVTVKKPVKASEVNQLLQKAAQGAFHGIV
                     DYTESPLVSIDFNHDPHSAIVDGTQTRVSGAHLIKTLVWCDNEWGFANRMLDTTLAMA
                     AVGFRLDASASTKL"
     gene            3969..4394
                     /locus_tag="OPV72_003938"
     CDS             3969..4394
                     /locus_tag="OPV72_003938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HCR9916108.1"
                     /translation="MTVSHHNASTARFYALRLLPGQEVFSQLHAFVQQNQLHAAWIAG
                     CTGSLTDVALRYAGQEATTSLTGTFEVISLNGTLELTGEHLHLAVSDPYGAMLGGHMM
                     PGCTVRTTLELVIGELPALTFSRQPCAISGYDELHISSR"
     gene            4420..4998
                     /locus_tag="OPV72_003939"
     CDS             4420..4998
                     /locus_tag="OPV72_003939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCR9916109.1"
                     /translation="MARRPFSSQSLVLIVIAIAINMIGGQLISMLKLPIFLDSIGTLI
                     SAVLLGPFIGMLTGLLTNLLWGLLTDPIAAAFAPVAMVIGLVAGWLARAGWFRTLPKV
                     IVSGVVITLAVTLVAVPLRTALFGGVTGSGADLFVAWMHSMGQNLVESVAITVIGANL
                     VDKILTAIIVWVLLRQLPLRTTRHFPAMSAVR"
     gene            4999..5706
                     /locus_tag="OPV72_003940"
     CDS             4999..5706
                     /locus_tag="OPV72_003940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HCR9916110.1"
                     /translation="MHPFTSLTLWALAACTTLLLPAQTVFPVYSAAAFLCLLALKSTR
                     RRAKYVAWLMLSLGFGLWLVHGGWLTEWISGQPRDPQRWVYAVTLWLRLLAIVSTSQL
                     WMQYVPVQRFIRALFASRLPPGIAYLFAGPLLVVEQLKRQLTIVHEAQRARGVPLDEG
                     WYQRLRAMPALIVPLTQNALNDLTIRGAALDMRGFRLHRARTTLWAPKDSMLQRVARY
                     GMVLLILAEAGVWIWLR"
     gene            5694..6371
                     /locus_tag="OPV72_003941"
     CDS             5694..6371
                     /locus_tag="OPV72_003941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HCR9916111.1"
                     /translation="MVTLEQFRYLPSDATRPPACFDFHYSTPGIVAIVGDNGSGKSTL
                     AQLMAGWYPDYLPGDIDGTGLLLGVPIGRLPLVEQSPTIHLVQQSPYLQLSGCTFSVE
                     EEVAFGPENLGLHEAEILRRIDEALTLTNCQSLRHRHPGTLSGGETQRVVIASALAMQ
                     PRLLVLDEAFSRLTSAATGTLLERLQQWALERHSLIVLFERNHFPFLTRCQRVWQLRN
                     GALTPLC"
     gene            6365..>7014
                     /locus_tag="OPV72_003942"
     CDS             6365..>7014
                     /locus_tag="OPV72_003942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCR9916112.1"
                     /translation="MLTLNQVAYRWPDAAADCLHAISLELRDGEWLALTGDNGAGKST
                     LLRIMAGLLSPTSGSVTLNGEPIAQLKNRQRAAAIGVLFQEAENQIFHSNVAQEVAFG
                     LKLQRLSAEDISRRTQAALRLCQLTDVAEAPPLDLHAAQRRMVAVASLEAMAPPVLLL
                     DEPSRDFDAHWLTVFEHWLATCRARGTSVVAISHDAAFTRRHFSRVVRLENGRLSKG"
BASE COUNT         1490 a         1918 c         1907 g         1699 t
ORIGIN      
        1 cccttttgat ttcttgttga acttttgcag ttgccagacc gcaagatgtt ttaacaaatc
       61 aaaaggggtt ttaataactg gcttaaagct gaaagctttc cggaaccccc agcctagctg
      121 ggggttttcc atagacaaaa aaatggcttc ccgagggaag ccatttcaat cagcagacta
      181 tattacagaa cgtcaatcgc gttcagttct ttaaatgctt tttccagacg agcgatcatc
      241 gaagtctggc cagcacgcag ccatacgcgc gggtcatagt atttcttgtt cggctgatct
      301 tcgcctttcg ggttgcccag ctgaccttgc agatacgctt cgttttcttt gtagtaattc
      361 agaacacctt cccaggttgc ccattgggta tcggtatcga tgttcatttt cactacgccg
      421 tagcttacgg agtctttgat ttcctgagca gtagaaccgg aaccgccgtg gaaaacgaag
      481 ttcaggctgt tgtgcggcag gttgtgtttc ttagaaacat agtcctgaga atcacgcagg
      541 atggtcgggg tcagaaccac gttacccggc ttgtaaacgc cgtgtacgtt accgaaggaa
      601 gcggcaatgg tgaaacgcgg gctgattttg ctcagctcag tgtacgcgta atcaacatct
      661 tccggctggg tgtacagagc agaagcgtcc atgtggctgt tgtccacgcc gtcttcttcg
      721 ccaccggtgc aacccagttc gatttccaga gtcatgccaa ttttggacat gcgcgccagg
      781 tatttggagc agatttcgat gttttcgtgc agagactctt cagacaggtc aatcatgtga
      841 gaagagaaca gcggtttacc ggtagccgcg aagtgttttt cacccgcgtc cagcagaccg
      901 tcgatccacg gcagcagttt cttcgcgcag tggtcagtgt gcaggataac cggcacgccg
      961 tagtgttcag ccatctggtg aacgtgatgc gcgccagaga tagcgcccag gattgccgcg
     1021 ccctgaggta cgtcagtttt cacgccttta cccgcgatga aggacgcgcc gccgttggaa
     1081 aactgaacga tgaccggtgc tttaactttt gcagcggttt ccagaacagc gttgatggaa
     1141 tcagtgccca cgcagttaac tgccggcaga gcaaaattgt tttcttttgc tacctggaac
     1201 actttctgta cgtcatcacc agtgatcacg cctggtttta cgaaatcaaa aattttagac
     1261 atgtttcgtt gtcctgtatc gtcgggcttt gggaaaaaac acgggccgcc ctgaatgtca
     1321 gatcggcgat aaatcaacgg gcaggaatcc ctgcccgtaa cgattacttc ttagcgcgct
     1381 cttcgagcat cgctacggct ggcagaactt taccttccac gaattcgagg aatgcgccgc
     1441 cgccagtaga aatgtaggaa attttgtcag caatgccgaa caggtcgatt gccgccaggg
     1501 tgtcgccgcc gccagcgatg gaaaacgctt cgctatcagc gatggcattc gccacgattt
     1561 cagtcccttt acggaagttc gggaactcaa acacgccaac cgggccgttc cacagaatgg
     1621 ttttggcatt cttgaggatt tcagccagct gctgagcgga agcatcgccg atatccagga
     1681 tctgctcgtc ttctttcacg tcgttaacgg atttcagagt cgctggtgcg gtttcggaga
     1741 actcggtggc aacgcgaaca tcggtcggaa ccgggatatc gcaagtggtc agcagacgtt
     1801 ttgcttcgtc aaccaggtca gcttcgtaca gggatttacc gacgctgtgg ccctgagcgg
     1861 caacgaaggt gttggcgata ccgccgccga caatcagctg gtcagcgatt ttagacaggg
     1921 aatccagaac agtcagtttg gtagatactt tagaaccacc aacgatagcc accatcggac
     1981 gagccggctc tttcagcgct ttacccagtg catccagttc agcggccagc agcgggcctg
     2041 cgcacgcgac gtcagcaaat ttgccgatac cgtgggtaga agcctgcgcg cggtgcgcag
     2101 taccaaaggc gtccatcaca aatacgtcac acagggcggc atatttttta gacagcgctt
     2161 cgtcgtcttt cttttcgcct ttgttaaagc gaacgttttc cagaaccacc agctcacctt
     2221 cggccacgtc aacgccgtcc aggtaatctt tgaccaggcg aaccgggtta gacagtttgt
     2281 ctttcaggta gttaacaacc ggcagcagag agaattcttc gttgtactcg ccttcggtag
     2341 gacgacccag gtgggaagtt accatcactt tcgcgccctg tttcagagcc agttcgatgg
     2401 tcggcagaga agcgcggata cgcgcgtcgc tggtcacttt cccttcttta acaggtacgt
     2461 tcagatccgc acggataaaa acgcgtttcc cggccagatc cagatcggtc atcttaatta
     2521 cagacatggt gaatcctctc aatgatgctt aaagttttgt cgacgctgac gcgtcgagcc
     2581 tgaaaccaac tgcggccatc gctaacgtgg tgtcgagcat cctgttagca aagccccatt
     2641 cattatcgca ccagaccagc gtcttgatca ggtgggcgcc actgacccgg gtttgcgtgc
     2701 catcaacaat ggcgctgtgc gggtcgtggt taaaatctat cgagaccaac ggtgattccg
     2761 tatagtcaac tataccatga aatgcacctt gtgctgcttt ttgcagcaac tggttgactt
     2821 cactagcttt tactggtttt ttcaccgtta cgcttaaatc gatcgccgtc acattaatgg
     2881 ttggaacgcg caccgcaatc gcctcaaaac ggtcgttaaa ctgcgggaat atacgcgtaa
     2941 tgcctgccgc cagttttgta tctaccggga taatcgactg gctggccgcg cgcgtgcgcc
     3001 gtagatcgga gtgatacgcg tcgatcacct gctgatcgtt catcgcggag tggatcgtcg
     3061 tgacggtacc agactcgatg ccgtaagcat catccaacaa tttaatgacg ggaattatgc
     3121 aattcgtggt acaggacgcg tttgagacaa tacgatgttc cgcacgcagt tggttctggt
     3181 tcacgccaaa aacgacggtg gcgtcaagat cgttgctgcc cggatgagaa aagagcactt
     3241 tcttcgcgcc agcggcaata tgcgcctcgc catgctcccg gttgccatat acgcccgtac
     3301 aatccaacac gacatccacg cccagttcgc gccacggcag atccgccagc gttcgttcat
     3361 gcagaatacg aatgacatcg tcgccgacaa aaagctgctc gcgctcgtgg cgaacctccc
     3421 atgcaaaacg cccgtggctg gtatcgtatt tcaacaaatg cgccatgcct gcggcatccg
     3481 ccagctcgtt gatggccacc acggtaattt ccgcccgacg tccggattca tacaaagcac
     3541 gaaccacgtt acgcccgatg cgaccaaagc cattaatcgc tatgcgtacg gtcataggtc
     3601 tcctgcaagg ctatcccgat tcagatgagg ctgacagagt aatgcagctt atcgtcgagt
     3661 aaaacctcac ctgtcgcaaa ctgcgactga ttggttaatt gtcgaacatt taattaactg
     3721 aaacgcttca gctagaataa gcgaaacggg gaataaaagg aatgtttgtc cagtcgaaga
     3781 agacagttat ctgacctgca tcacatttca tggccgctta cgctgcaatt tattccatat
     3841 ttaagaatca ccagtacatc cgtcagatct tttcatcgtc gcgtcacaaa tactgattta
     3901 tatcagaaag cgctgtcgcc agcgtctata ttatcagcgc cacgtccgag tctcggagtc
     3961 ctgtaacgat gactgtatct caccacaatg cctctacagc gcgcttttac gcgcttcgtc
     4021 tgcttcccgg ccaggaagtg ttttcccaat tacacgcctt tgtgcaacag aaccaattac
     4081 atgccgcctg gattgcaggg tgtaccggca gtctgaccga cgttgcgctg cgttatgccg
     4141 ggcaagaagc gaccacatcg ctcaccggca cgtttgaagt tatctcgcta aacggcacgc
     4201 ttgaattgac cggcgagcat ctgcatctcg cggtatcgga tccctacggg gccatgctcg
     4261 gcggccatat gatgccaggg tgtaccgtgc gtaccacgct ggagctggtt atcggcgagc
     4321 tgccagcgct gacgttcagc cgtcaaccgt gcgccatttc cggttatgac gaactgcata
     4381 tttcttcccg ttaattgacg actctttaag aggtacttta tggcgcgtcg cccgttttcc
     4441 agccagtctc tggtgctgat tgtcatcgct attgccatca atatgattgg cggacagctt
     4501 attagcatgt tgaagctgcc tatttttctc gactcgatcg gcaccttaat tagcgcggta
     4561 ctgttagggc cgttcatcgg catgttgact gggcttctga ccaacttgct gtgggggctg
     4621 cttaccgacc ctatcgctgc cgcgtttgcc ccggtagcga tggttatcgg tctggtcgcc
     4681 gggtggctgg cgcgcgcagg ctggtttcgt accctgccca aagtgatcgt cagcggggtc
     4741 gtcattacgt tggcggtgac gctggtcgcc gtaccgcttc gtaccgcgct ttttggcggc
     4801 gttaccggta gcggcgctga tttgttcgtc gcctggatgc attcaatggg ccaaaacctg
     4861 gtggagtcag tcgcgattac cgtcataggc gctaatctgg tcgataaaat tctgacggcg
     4921 atcatcgttt gggtgctgct gcgtcagcta ccgttacgta cgacacggca ttttcctgcg
     4981 atgtcagccg tacgctaaat gcatccgttt acctcgttaa ccttatgggc gttggcggcc
     5041 tgcaccacgc tgctactccc tgcgcagacc gtgttcccgg tttatagcgc ggcggccttc
     5101 ctctgtctgc tggcgctgaa atcaacgcgg cggcgggcga agtatgtcgc ctggctgatg
     5161 ctgtctttag ggtttgggct atggctggta catggcggtt ggctaacgga atggataagc
     5221 gggcagcctc gcgatccgca gcgctgggta tatgccgtta cgctatggct acgtctgctg
     5281 gcgatcgtgt cgacgtcgca gctatggatg cagtatgtgc cggttcagcg gtttattcgc
     5341 gccctgttcg cttcacgtct gccacccggc atcgcttacc tgttcgctgg cccgctgctg
     5401 gtcgtcgaac agctcaaacg acaactgacg atcgttcatg aagcccagcg cgcgcgcggc
     5461 gtaccgctgg atgaaggctg gtatcagcgg ctacgggcaa tgcctgcgct gatcgtgccg
     5521 cttacgcaaa atgcgcttaa cgatctgaca atacgcggcg cggcgttgga tatgcggggg
     5581 tttcggctgc atcgagcccg aaccacgctg tgggcgccga aagatagcat gttacaacgg
     5641 gttgcgcggt atggcatggt actgctaata ctggcggaag cgggagtatg gatatggtta
     5701 cgttagagca gtttcgttat cttccgtccg atgcgacacg cccgccggca tgttttgatt
     5761 tccactattc aacacccgga atagtggcga tagtcggcga taacggcagc ggaaaaagta
     5821 cgctggcgca actgatggct ggctggtatc cggattatct ccccggcgat attgacggca
     5881 caggcctact gcttggcgta cctatcgggc ggctcccgct ggtagaacag tcgcccacca
     5941 tccacctggt gcagcaatcg ccttatttac agctttccgg ctgtaccttt agcgtagagg
     6001 aagaggtggc gtttggcccg gagaatctcg gcctccatga agcggaaatt ctacggcgca
     6061 ttgacgaggc gctgactctg acaaactgcc agtcgttacg ccatcgccat cccggcacgc
     6121 tctccggcgg cgaaacgcag cgggtagtga ttgccagcgc gcttgccatg cagcccagat
     6181 tattagttct tgatgaagcc ttcagtcggc tgacgtcagc ggccaccggg acactgctgg
     6241 aacggttaca acagtgggcg ctggaacgtc attctctcat tgtgcttttt gagcgtaatc
     6301 atttcccctt tctgacgcga tgccagcggg tatggcaatt gcgcaacgga gcgctaaccc
     6361 cattatgttg acgttaaatc aggtcgctta tcgctggcca gatgccgcag ccgactgtct
     6421 gcacgccatc tcgcttgaac ttcgtgacgg cgaatggctg gcgttgaccg gcgataacgg
     6481 cgcgggaaaa tcaacgctgt tacggattat ggccggcctg ctttccccca cttccggctc
     6541 ggtaacgctt aatggagagc cgattgcgca gcttaaaaat cgtcaacgcg ccgccgctat
     6601 cggcgtactc tttcaggaag cggaaaacca gattttccac agcaatgtcg cacaagaggt
     6661 cgcttttggg ctgaaactac agcgcttatc ggcggaggat atttcacggc gcacgcaggc
     6721 cgcgctgcgg ttatgccagc taacggacgt cgccgaggcg cccccgcttg atctgcacgc
     6781 cgcgcagcgc cggatggtgg cggtcgccag tctggaggcg atggcgccgc cggtgttatt
     6841 gctggatgaa cccagccggg attttgacgc ccactggcta accgtatttg aacactggct
     6901 ggcgacatgc cgggcacggg gaaccagcgt cgtggcgatt agccatgacg ctgcgtttac
     6961 ccggcgtcat ttttcccggg tggtacggct ggaaaacggc aggttgtcaa aggg
//
LOCUS       DAJVBX010000216         6970 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.216, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000216 DAJVBX010000000
VERSION     DAJVBX010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 6970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6970
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.216"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            57..965
                     /gene="galU"
                     /locus_tag="OPV72_003943"
     CDS             57..965
                     /gene="galU"
                     /locus_tag="OPV72_003943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HCR9916113.1"
                     /translation="MAALNSKVKKAVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQY
                     VVNECIAAGITEIVLVTHSSKNSIENHFDTSFELEAMLEKRVKRQLLEEVQSICPPHV
                     TIMQVRQGLAKGLGHAVLCAHPVVGNEPVAVILPDVILDEYESDLSQDNLAEMIRRFD
                     ETGNSQIMVEPVEDVTAYGVVDCKGVELAPGESVPMVGVVEKPKADVAPSNLAIVGRY
                     VLSADIWALLAKTPPGAGDEIQLTDAIDMLIEKETVEAYHMKGKSHDCGNKLGYMQAF
                     VEYGIRHNSLGAEFKAWLEEEMGIKK"
     gene            complement(1097..1510)
                     /gene="hns"
                     /locus_tag="OPV72_003944"
     CDS             complement(1097..1510)
                     /gene="hns"
                     /locus_tag="OPV72_003944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator H-NS"
                     /protein_id="HCR9916114.1"
                     /translation="MSEALKILNNIRTLRAQARECTLETLEEMLEKLEVVVNERREEE
                     SAAAAEVEERTRKLQQYREMLIADGIDPNELLNSMAAAKSGTKAKRAARPAKYSYVDE
                     NGETKTWTGQGRTPAVIKKAMEEQGKQLEDFLIKE"
     gene            2173..2790
                     /gene="tdk"
                     /locus_tag="OPV72_003945"
     CDS             2173..2790
                     /gene="tdk"
                     /locus_tag="OPV72_003945"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HCR9916115.1"
                     /translation="MAQLYFYYSAMNAGKSTALLQSSYNYQERGMRTVVYTAEIDDRF
                     GAGKVSSRIGLSSPAKLFNQNTSLFEEIRAESARQTIHCVLVDESQFLTRQQVYQLSE
                     VVDKLDIPVLCYGLRTDFRGELFVGSQYLLAWSDKLVELKTICFCGRKASMVLRLDQD
                     GRPYNEGEQVVIGGNERYVSVCRKHYKDALEEGSLTAIQERHRHI"
     gene            complement(2987..5665)
                     /gene="adhE"
                     /locus_tag="OPV72_003946"
                     /gene_synonym="adhC"
     CDS             complement(2987..5665)
                     /gene="adhE"
                     /locus_tag="OPV72_003946"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HCR9916116.1"
                     /translation="MAVTNVAELNALVERVKKAQREYASFTQEQVDKIFRAAALAAAD
                     ARIPLAKMAVAESGMGIVEDKVIKNHFASEYIYNAYKDEKTCGVLSEDDTFGTITIAE
                     PIGIICGIVPTTNPTSTAIFKSLISLKTRNAIIFSPHPRAKEATNKAADIVLQAAIAA
                     GAPKDLIGWIDQPSVELSNALMHHPDINLILATGGPGMVKAAYSSGKPAIGVGAGNTP
                     VVIDETADIKRAVASVLMSKTFDNGVICASEQSVVVVDSVYDAVRERFASHGGYMLQG
                     QELKAVQNVILKNGALNAAIVGQPAYKIAELAGFSVPETTKILIGEVTVVDESEPFAH
                     EKLSPTLAMYRAKDFEEAVEKAEKLVAMGGIGHTSCLYTDQDNQPERVAYFGQMMKTA
                     RILINTPASQGGIGDLYNFKLAPSLTLGCGSWGGNSISENVGPKHLINKKTVAKRAEN
                     MLWHKLPKSIYFRRGSLPIALDEVITDGHKRALIVTDRFLFNNGYADQITSVLKAAGV
                     ETEVFFEVEADPTLSVVRKGAELANSFKPDVIIALGGGSPMDAAKIMWVMYEHPETHF
                     EELALRFMDIRKRIYKFPKMGVKAKMIAVTTTSGTGSEVTPFAVVTDNATGQKYPLAD
                     YALTPDMAIVDANLVMDMPKSLCAFGGLDAVTHALEAYVSVLASEFSDGQALQALKLL
                     KENLPASYHEGSKNPVARERVHSAATIAGIAFANAFLGVCHSMAHKLGSQFHIPHGLA
                     NALLICNVIRYNANDNPTKQTAFSQYDRPQARRRYAEIADHLGLSAPGDRTAAKIEKL
                     LAWLESIKAELGIPKSIREAGVQEADFLAHVDKLSEDAFDDQCTGANPRYPLISELKQ
                     ILLDTYYGRDFTEGEVAAKKDVVAAPKAEKKAKKSA"
     gene            6142..6789
                     /locus_tag="OPV72_003947"
     CDS             6142..6789
                     /locus_tag="OPV72_003947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YchE family NAAT transporter"
                     /protein_id="HCR9916117.1"
                     /translation="MIQPLFDFPVYFKFFIGLFALVNPVGIIPVFISMTSYQTATARN
                     KTNLTANLSVAIILWSSLFLGDGILQLFGISIDSFRIAGGILVVTIAMSMISGKLGED
                     KQNKQEKSETAIRESIGVVPLALPLMAGPGAISSTIVWGTRYHSIAHLLGFSVAIALF
                     ALCCWGVFRMAPWLVRLLGQTGINVITRIMGLLLMALGIEFIVTGIKGIFPGLLN"
BASE COUNT         1711 a         1596 c         1786 g         1877 t
ORIGIN      
        1 acacgataca gattaatgaa cacgttcaat acatgaacag tccaggagaa ttttaaatgg
       61 ctgcccttaa ttcgaaagtc aaaaaagccg ttatcccggt cgcgggattg ggaaccagga
      121 tgctgccagc gaccaaagct atcccgaaag agatgctgcc gctggttgat aagccattaa
      181 ttcagtacgt cgtgaacgaa tgtatcgctg ctggcattac tgaaatcgtg cttgttacgc
      241 actcgtctaa aaactctatt gaaaaccact ttgataccag ttttgagctg gaagcgatgc
      301 tggaaaaacg cgttaagcgt cagcttctgg aggaggttca gtctatttgc cctccgcatg
      361 tcactattat gcaggtacgt caagggctgg caaaaggcct gggccatgcc gtattgtgcg
      421 cgcatcccgt tgtcggaaac gaacctgtcg ctgttattct gccagacgtt attcttgacg
      481 aatatgagtc cgacctgtct caggataacc tggctgaaat gatccgccgt ttcgacgaaa
      541 ccggcaatag ccagattatg gttgagccag tagaagatgt gactgcatac ggcgtggtcg
      601 attgcaaagg cgttgagctg gcgccgggcg aaagtgtgcc gatggttggc gtggttgaaa
      661 aaccaaaagc ggatgtcgcg ccgtctaacc ttgcgattgt cgggcgttat gtgttgagcg
      721 cggatatctg ggcgttgctg gcgaaaaccc ctccgggcgc cggggatgaa attcagttga
      781 ccgatgctat cgatatgctg atcgaaaaag aaacggttga agcctaccac atgaagggta
      841 aaagccatga ctgtggtaat aagttaggat atatgcaggc attcgttgaa tatggcatcc
      901 gtcataattc gctgggtgct gaatttaaag cctggcttga agaagaaatg ggtattaaga
      961 agtaacgata cgttataaat tttttaacag aagcgctggt aaatccggcg ctttttttat
     1021 gcctggggtc gtcagcggag aactcaggca aaaaaaatcc cgccagcggc gggattttaa
     1081 gcatccagga agtaaattat tccttgatca ggaaatcttc cagttgctta ccttgttctt
     1141 ccattgcttt tttgattaca gccggtgtac gaccctggcc agtccaggtt ttagtttcac
     1201 cgttttcgtc aacatagcta tatttagccg gacgagctgc gcgtttagct ttggtaccgg
     1261 atttagcggc agccatgcta ttcagcagtt cattcgggtc aatgccgtcg gcaattaaca
     1321 tttcacgata ctgttgcagt ttacgagtgc gttcttccac ttcagcagca gcagcgcttt
     1381 cttcttcacg acgctcatta acgacaactt ctaatttttc cagcatttct tcaagcgttt
     1441 ccagagtaca ttctcttgcc tgcgcacgaa gagtacggat gttgttcaga attttaagtg
     1501 cttcgctcat tgtagtaatc tcaaacttat attggggtgg tttgttgagc taataataga
     1561 gcgataaatt cagttgtgca atagccagga atgtaaggaa ttcaaaatta cgctttatta
     1621 agcacacgtt ttaattatct caacttaaat tttccttgag gcgccgcaca aaaaagagct
     1681 tattgccagg ggggatactc accgtctgtc actaaaaatt taggattcag gtcacatttt
     1741 atcatgatga aatacgatct cattgcagag atatcaatct cttgtattag ctttccttac
     1801 aagaaaaccc tattactttg cattgggtat gagtaacggt aacaataagt acaaggtttt
     1861 catattggcg ggtgatgata agcattgttg atgaatttta acggcataat ttgtgaagga
     1921 atgtgtatat acccttcata cttcaagttg cttatgtgtt ggctacgctc gcgcacccca
     1981 gccacatagt tatctatgct cctggggact cactcccttg ccgcctttaa gcaactcgaa
     2041 ttattttggg tatagtgagc gatgtttgta caattcttaa tactcaccgg agcgcgagcc
     2101 gcgccgtcgc atcggtaaat tatggtacaa tcccgccaat ctttatttca ctcaggtgag
     2161 gtcctgcgac caatggcaca gctatatttc tactattcgg caatgaatgc gggtaagtcg
     2221 actgcactgc tgcaatcttc atacaattat caggaacgcg ggatgcgtac cgtcgtatat
     2281 acggcggaaa tcgacgatcg tttcggcgca ggcaaagtca gctctcgtat cggtttgtcg
     2341 tcgccggcaa aattgtttaa ccaaaataca tccttgtttg aagagattcg tgccgagagc
     2401 gcgcggcaga caatacattg cgtgttagtc gacgaaagcc agtttttgac tcgccagcag
     2461 gtttatcaat tatccgaggt tgtcgacaaa ttagatattc cagtactctg ctatgggcta
     2521 cgaacagact ttcgtgggga gctctttgtc ggcagccaat acttgctggc atggtcagat
     2581 aagctggtgg aattaaaaac tatctgtttc tgcggtcgta aagccagtat ggttttgcgc
     2641 cttgatcagg acggcaggcc ttataacgaa ggcgaacagg tggttattgg cgggaatgaa
     2701 cgctacgttt cagtttgccg taagcattat aaggacgcgc tggaggaggg ctcactgacg
     2761 gcgattcagg agcgccatcg gcacatatga tacctgaggt aaagatcggc ttataaaacg
     2821 ccctgtagcg ctttggaggt cattattcag gcctcctgac gaagggcgtg ccgtgagcgc
     2881 gtaggccaga tggtaagcat agcgccttca ggcatcagat aaacaggtaa aacaaaaaaa
     2941 cggcctcaat tgaggccgtt attgtcatgc taaaacagat aacgaattaa gcggattttt
     3001 tcgctttttt ctctgctttc ggtgcggcaa cgacgtcttt cttcgctgca acttcacctt
     3061 cggtgaaatc acgaccgtag taggtatcca gcagaatctg tttcagttcg gagatcagcg
     3121 gataacgcgg gttagcgccg gtgcactggt catcgaaggc atcttcagac agtttgtcaa
     3181 cgtgtgccag gaagtcagct tcctgcacgc ctgcttcacg tatagactta ggaatgccca
     3241 gctcagcttt aatgctttcc agccatgcca gcagtttttc aatcttagcg gcggtacggt
     3301 cgcccggcgc gctcaggccc aggtggtcag caatttcagc gtaacgacgg cgtgcctgcg
     3361 gacgatcgta ctggctgaaa gcggtctgct tggtcgggtt gtcattcgcg ttgtagcgga
     3421 taacgttaca aatcagcagg gcgttcgcca gaccgtgcgg aatgtggaac tgagagccca
     3481 gtttgtgcgc catggagtga catacaccga ggaaggcgtt ggcaaacgcg ataccggcga
     3541 tagtcgctgc actgtgaaca cgttcacgcg caaccgggtt tttagaccct tcgtggtaag
     3601 acgccggcag gttttctttc agcagtttca gagcctgcag agcctgaccg tcagagaact
     3661 cagaagccag tacggaaacg taagcttcca gggcgtgagt taccgcatcc agaccaccga
     3721 acgcacacag ggacttcggc atatccatca ccaggttggc atcgacaatc gccatatccg
     3781 gggtcagggc atagtcagcc agcggatatt tctgaccggt tgcattgtcg gtcacaaccg
     3841 caaacggtgt gacttcagaa ccggtaccgg aagtggtggt gacggcgatc attttcgctt
     3901 tcacgcccat tttcgggaac ttgtagatac gtttacggat gtccataaag cgcagcgcca
     3961 gttcttcgaa gtgagtttcc ggatgttcgt acatgaccca catgattttc gcggcgtcca
     4021 tcggggaacc gccgcccagc gcgatgatca cgtccggttt gaaggagtta gccagctcag
     4081 cgcctttgcg aacaacggaa agcgtcgggt ctgcttcaac ttcgaagaag acttcggttt
     4141 caacgccagc cgctttcagc acagaggtga tctggtctgc atagccgttg ttgaacagga
     4201 agcggtcagt cacgatgagc gcacgtttgt ggccatcagt aatcacttca tccagcgcga
     4261 tgggcagaga gccacggcgg aagtagatag atttcggaag tttgtgccac aacatgtttt
     4321 cagctcgctt agcaacggtt ttcttgttga tcaggtgttt cggaccaacg ttttcagaga
     4381 tggagttacc accccaggaa ccacaaccca acgtcaggga aggtgcgagt ttgaagttgt
     4441 acaggtcacc gataccaccc tgagaggccg gggtgttgat caggatacgc gcggttttca
     4501 tcatctgacc gaagtaagca acgcgttctg gctggttatc ctggtcagtg tacaggcagg
     4561 aggtgtgacc gataccgccc atagcgacca gtttttctgc tttttctacc gcttcttcga
     4621 aatctttcgc acggtacatc gctagagtcg gagacagttt ttcgtgtgcg aacggttcgc
     4681 tttcgtcaac gaccgtaact tcaccgatca gaatcttggt ggtttctggt acggagaagc
     4741 ctgccagttc agcgattttg taggctggct gaccgacgat agcggcgttc agagcgccat
     4801 ttttcagaat aacgttttga accgctttca gctcctggcc ctgcagcatg tagccgccgt
     4861 ggctggcgaa acgttcgcga acggcatcat agacggaatc aacaacgaca acagactgtt
     4921 cagaagcaca gattacgccg ttatcgaagg ttttagacat cagaacagac gccacagcgc
     4981 gtttgatatc agcggtttca tcaatgacaa ccggggtgtt acctgcgcct acgccgattg
     5041 ccggtttacc ggagctgtat gcagctttaa ccatgcctgg accgccagtg gcgaggatca
     5101 ggttaatatc cgggtggtgc atcagcgcat tagacagttc tacggaaggt tgatcgatcc
     5161 agccaatcag atctttcggt gcgccggcag cgatagccgc ttgcagaacg atgtctgccg
     5221 ctttgttagt tgcttcttta gcgcgcggat gcggagaaaa gatgatggcg ttacgggtct
     5281 tcaggctaat cagcgatttg aagatcgcag tagaggtcgg gttagtggtt ggaacgatac
     5341 cgcaaataat gccgataggt tcagcaatgg tgatggtccc gaaggtgtcg tcttctgaca
     5401 gcacgccgca ggttttttca tctttatagg cattgtaaat atattcagaa gcgaagtggt
     5461 ttttaatcac tttgtcttcc acgataccca tacctgattc ggcgacggcc attttggcca
     5521 gcggaatgcg ggcatcagcg gctgccagag cggcggcgcg gaagattttg tcgacctgtt
     5581 cttgagtgaa actggcatat tcacgctggg ctttttttac acgctctacg agtgcgttaa
     5641 gttcagcgac attagtaaca gccataatgc tctcctgata atgttaaact tttttagtaa
     5701 atcatctgcg cgatacgtga gtatagacag atcgacgata ctttgtataa atacctgaaa
     5761 ttcaggtggt tacttaacgt ccgtttcgct ctgatttact aaaagagctt ctgcgttagt
     5821 atcatttaac tctaacgcgt tacgtccagg tggcgtaagc aagattactc acttctgagt
     5881 agcgattgtg tgatctaaat caagattacg caaagctgac acctttcagc aggccatttt
     5941 agccttttat gtaaattgtt aagaaatcgt tgtcatgaag agtaagtgga ttagcataac
     6001 gagtacatat aaataacagc gatgaatgga tgaaattagg tgtagataag aggtgaacta
     6061 tgcgaataaa aggcgtatct tctgcgcgtt ttgatcatta acgaacattg acttcatccg
     6121 gctaacgctt cggagctaac cgtgattcaa ccgctttttg attttcctgt ttactttaag
     6181 ttctttatcg ggctctttgc gctggttaac ccggtgggga ttattcccgt tttcatcagc
     6241 atgaccagct accagacggc cacggcgcgt aataaaacta acctcaccgc gaatctgtcg
     6301 gtcgcgatta tcttgtggag ttccttattc ctcggcgatg gcatcctgca gctgtttggt
     6361 atttctattg attcgttcag aattgcgggc ggtatcctgg ttgtcaccat tgcaatgtcg
     6421 atgatcagcg ggaagctggg ggaagataaa caaaacaagc aagaaaagtc agagacggcc
     6481 atacgcgaga gcattggcgt tgtgccgtta gcgctaccgt taatggcggg gccaggggcg
     6541 attagctcca ctatcgtctg ggggacgcgt tatcacagca tcgcgcattt gcttggtttt
     6601 tcagttgcca ttgcgctttt tgcgctttgc tgctggggcg tgttccgtat ggcgccgtgg
     6661 ctggttcgtt tgctggggca aaccggtatc aacgttatta cccgaatcat ggggttgttg
     6721 ttaatggcgc tcggcatcga atttattgtc acaggaataa aaggcatttt ccccggcttg
     6781 ctcaactaaa ctcccacctg ttgatttaca ggcggcgccc taagggggcc gccttgtgac
     6841 attcccagtg acattcccac gtaacacttc ttactttgat aagcattcag cgtttaaatg
     6901 ataaaaaata ctaatataat ctaacgctat ttatttttat taatcaatct attatgaaca
     6961 ttactgagac
//
LOCUS       DAJVBX010000217         6946 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.217, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000217 DAJVBX010000000
VERSION     DAJVBX010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 6946)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6946)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6946
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.217"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..551)
                     /locus_tag="OPV72_003948"
     CDS             complement(<1..551)
                     /locus_tag="OPV72_003948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HCR9916118.1"
                     /translation="MLLITDLDGTLLTSQKTISPRTRQALIAFRQDGSLLAACSARPV
                     SSMVRLLHQQQVDRLFSWCAGFNCGHLLEMAGQRIIHAAPLSATDLWNIDQHISLSRY
                     HHHFFSAEAIHHRDDRLIAPWTTYEARLFGLPLITETTENIFNRRDIYKITLVAVSSE
                     IDTLCTEVNNHLPYGYYAVVTGE"
     gene            complement(568..1407)
                     /locus_tag="OPV72_003949"
     CDS             complement(568..1407)
                     /locus_tag="OPV72_003949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine biosynthesis protein"
                     /protein_id="HCR9916119.1"
                     /translation="MFKGDMNKKRAKALQKVKEAITLHGGQTILSTGITGDDARLAKA
                     VCEAGVKLLEPNHPALALARGHKGVSNMHAAEQIRHEITNSQMAEAVHGVRNVVPDDI
                     FITVGIAGGFTETLPVPLSETEILEIARAGADGLHTHKSDWDDLQDIVNLAHQYGLTV
                     DAYIGHPDDLHTFGIPARTPEEVASVAKRMQDIGVDMIGLMTGMSYEGVAAGDIPQMI
                     KDRLRALVGAVDVPTLAEGGINLANAKAFKDTGVNILVVGTAIDNMVCNAAKEAVTPF
                     IVH"
     gene            complement(1431..3011)
                     /locus_tag="OPV72_003950"
     CDS             complement(1431..3011)
                     /locus_tag="OPV72_003950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000716843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter"
                     /protein_id="HCR9916120.1"
                     /translation="MAIIGSSGGNLYNLGGAEPEKLLQEIYQQCEAAGVNVAAVQFIA
                     AEASMDVAKPDTPASVYALTTENQQKPQRIFQGKLSEVNTSVVESDRQIAEMIRRGEI
                     DGIVVMSADPVKANQAVFAAAVEMKTPIVGTGGTSMALVAAKGANVVATSGTTGTTSR
                     TRAVSFVASLCKHWGIKYKPQLGSASPSQSGSGKSLLKRFNIRSIMIPALPGFIAMAI
                     VLALSHIPGLEKLNDIFEILLKGLPVLVAVLAAKQISELDEVSIVAGVVAGVLSVEGG
                     LIGGIIGGVMAGIFVRWLFELCLNWRFPMTTVNIVAGGISGLAAGLIMHYLLSPLALS
                     AGNYIKLAIESTLAFSPILAGLLAGLVIWPAILGGVYHAVILPLVLLEMEKSGVSFLG
                     AVDMVGLVMVAAGINLANVIAPREKSEAAVATPGLLINLGFGTFVESAYPFMFANKIV
                     FGSAIFWAGMGGMMLGFFNVKGVAYVPAFASPFLSSNALQMAIVMIATMAMTCLTTII
                     ANRFKPVVQSESTTTAVN"
     gene            complement(3417..4766)
                     /gene="lysC"
                     /locus_tag="OPV72_003951"
     CDS             complement(3417..4766)
                     /gene="lysC"
                     /locus_tag="OPV72_003951"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine-sensitive aspartokinase 3"
                     /protein_id="HCR9916121.1"
                     /translation="MTEIVVSKFGGTSVADFDAMNRSADIVLSDANVRLVVLSASAGI
                     TNLLVALAEGMEPGERFATLDAIRKIQFDILDRLRHPNVIREEIERLLENITILAEAA
                     SLATSAALTDELVSHGELMSTLLFVEILRERDVQAHWFDVRKVMRTSDRFGRAEPDVA
                     ALAELAAQQLLPRLSETLVITQGFIGSESKGRTTTLGRGGSDYTAALLAEALHAARVD
                     IWTDVPGIYTTDPRVVPVAQRIDEIDFEEAAEMATFGAKVLHPATLLPAVRSDIPVFV
                     GSSKDPQAGGTLVCNKTQNPPLFRALALRRNQTLLTLHSLNMLHSRGFLAEVFGILAR
                     HNISVDLITTSEVSVALTLDTTGSTSTGDTLLTQSLLMELSALCRVEVEEGLALVALI
                     GNNLSKACGVGKEVFGVLEPFNIRMICYGASSHNLCFLVPGDDAEKVVQKLHQNLFE"
     gene            5155..6804
                     /gene="pgi"
                     /locus_tag="OPV72_003952"
     CDS             5155..6804
                     /gene="pgi"
                     /locus_tag="OPV72_003952"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HCR9916122.1"
                     /translation="MKNINPTQTSAWQALQKHYDEMKDVTIAELFANDSDRFAKFSAT
                     FDDLMLVDFSKNRITEETLAKLQDLAKETDLAGAIKSMFSGEKINRTEDRAVLHVALR
                     NRSNTPIIVDGKDVMPEVNAVLEKMKTFSQAIISGQWKGYTGKAITDVVNIGIGGSDL
                     GPFMVTEALRPYKNHLTMHFVSNVDGTHIAEVLKKVNPETTLFLVASKTFTTQETMTN
                     AHSARDWFLKSAGDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSA
                     IGLSIILSVGFDNFVELLSGAHAMDKHFSTTPAEKNLPILLALIGIWYNNFFGAETEA
                     ILPYDQYMHRFAAYFQQGNMESNGKYVDRNGNAVDYQTGPIIWGEPGTNGQHAFYQLI
                     HQGTKMVPCDFIAPAITHNPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQGKD
                     PAQLEHVVPFKVFEGNRPTNSILLREITPFSLGALIALYEHKIFTQGVILNIFTFDQW
                     GVELGKQLANRILPELGDDKAISSHDSSTNGLINRYKAWRA"
BASE COUNT         1668 a         1864 c         1806 g         1608 t
ORIGIN      
        1 ttttctcccg tgacgaccgc ataatatcca taaggcaggt gattattcac ttctgtacac
       61 agtgtatcta tctccgaaga tacggcaaca agggtaattt tatatatatc gcgacgatta
      121 aagatatttt ctgtagtttc agttataagc ggcaacccaa ataagcgggc ttcatatgtt
      181 gtccagggcg caatcagtct atcgtcacga tggtgaattg cttcggcgct aaaaaaatgg
      241 tggtgatagc gggaaagaga aatatgctgg tcaatattcc acagatctgt ggcggacaac
      301 ggagcagcat gaataatgcg ctgccccgcc atctccagaa gatgtccgca gttaaaaccg
      361 gcgcaccagc taaacaacct atcaacctgt tgttggtgta gcaggcgtac cattgaggag
      421 accggtctgg cggaacatgc cgccagcaga ctaccgtcct ggcggaacgc aatcagcgcc
      481 tgacgcgtgc gcgggctgat tgttttctgc gaggtgagta atgttccatc cagatcggtg
      541 attaacaaca tctctcgttc cctgatatca atgaacaata aacggcgtaa cggcttcttt
      601 ggcggcgttg cacaccatgt tgtcgatagc cgtaccgacc accagaatat tgactccggt
      661 atctttaaac gctttcgcgt tggcgaggtt aatcccgcct tccgccagcg tcggaacatc
      721 caccgcgccg accaacgccc gcaggcgatc tttaatcatc tgcgggatat cgcctgccgc
      781 tacgccttca tagctcatgc ctgtcatcag accaatcata tccacgccga tatcctgcat
      841 ccgcttcgcc acgctggcga cctcttccgg cgtgcgtgca ggaataccga aagtatgcag
      901 atcgtcagga tggccaatgt aggcatcgac ggtcagacca tattgatggg cgagattaac
      961 gatgtcctgc agatcgtccc agtcggattt atgcgtatgt aaaccgtcgg ctccagcgcg
     1021 ggcaatctcc agaatttccg tttcgctgag cggcaccggt aaggtttcgg taaaaccgcc
     1081 ggcgatacca acggtgataa aaatatcgtc cgggaccaca ttacgaacac cgtgtacggc
     1141 ctcagccatc tggctattgg tgatttcgtg acgaatctgc tccgccgcgt gcatgttgct
     1201 cacgcctttg tgtccacgcg ccagcgccaa cgcagggtgg ttcggctcca gaagcttaac
     1261 gccagcctca cacacggctt tcgccaggcg cgcatcgtcg ccagttattc ctgtgctgag
     1321 gatagtttgc ccaccgtgaa gcgtgatggc ttctttcact ttctgtaacg ctttggcgcg
     1381 ttttttattc atatcgcctt taaacatggt gtacctctgg tgttggtgca ttaattaacg
     1441 gctgtcgttg ttgattcgct ctgtacgaca ggtttgaaac ggttagcaat aatggtggta
     1501 aggcaggtca tcgccattgt ggcaatcatt acgatggcca tctggagcgc attgctggat
     1561 aagaacggtg aggcgaaagc cggaacatag gccacgcctt tgacgttaaa aaagcccagc
     1621 atcatgccgc ccattccggc ccaaaaaatg gcggagccaa aaacaatttt gttggcgaac
     1681 atgaagggat aggcggattc aacaaaggtg ccaaaaccca ggttaatgag caggcccggc
     1741 gtagcaacgg cagcttcgct tttttcacgc ggggcgatca cattggcaag gttaatacct
     1801 gcggccacca tcaccagacc gaccatatcg accgcgccga ggaagctgac gccggatttt
     1861 tccatctcca gcagtaccaa cggcaggatc accgcgtgat agacgccgcc gagaatggca
     1921 ggccagataa ccagaccagc cagcagcccg gcaagaattg ggctgaatgc cagcgtgctt
     1981 tcgatagcca gtttgatgta attacccgca gatagcgcca gcggactcag cagatagtgc
     2041 atgattaacc cagcggcaag gcccgatatc ccaccggcga cgatgttgac ggtagtcatt
     2101 gggaagcgcc agttcaggca cagctcgaac agccaacgga cgaaaatccc cgccattaca
     2161 ccgccgataa tgccgccgat cagtccgccc tctacggaaa gcacgccagc gacgacccca
     2221 gccacaattg aaacttcatc cagttcggaa atctgttttg ccgccagtac cgcgactaac
     2281 actggcagac cttttagtaa tatttcaaag atatcgttaa gtttttccag tcctggtatg
     2341 tggctcaggg cgagtacaat cgccatggcg ataaagcctg gtagcgcagg gatcatgatg
     2401 ctacgaatgt taaaacgttt gagcaggctt tttccggaac cgctctgcga gggcgaagcg
     2461 ctacccaact gtggtttgta cttgataccc caatgtttac atagtgacgc cacgaaggag
     2521 acggcgcggg tacggctggt ggtgccggtt gttccggagg tcgcgaccac attcgccccc
     2581 tttgccgcca ccagcgccat ggaggttccc ccggtgccga caatcggtgt tttcatctca
     2641 acggcggcgg caaaaacggc ttggttcgcc tttaccggat cggcgctcat taccacgatc
     2701 ccatcgatct caccgcggcg gatcatctca gcgatttggc gatcgctttc tactaccgag
     2761 gtgtttacct ccgaaagctt accctgaaat atgcgctgtg gtttttgttg gttttctgtg
     2821 gttaatgcat aaaccgatgc cggggtgtcc ggtttggcga cgtccatcga ggcctctgcc
     2881 gcgataaatt gtacggcggc cacattcacg cccgcagcct cacactgctg ataaatctcc
     2941 tggagtaact tctctggctc ggcgccaccc aggttgtaga ggttgcctcc actgcttcca
     3001 ataatcgcaa ttttttcata gcggcctcaa atagggtaag ggggttatct gtgttgtagt
     3061 gcaatcataa ttccaactaa aacaaaataa agcaacaatg aaaaagtgct tttataccaa
     3121 acgatctcaa tttttaaagg taagttatta aaatataatg ataaatttat gtttttgttt
     3181 tgtgttgttt tgcgtggttt tgtgacgagg ttcaaaatga ggagggcata aataggggaa
     3241 agctgcccat attgatggga cgagcagggt gtacagattc ctgccttctg taattggctt
     3301 tctggagcag tattccgccg gcagtgcctg acgtgggaac cgccggataa ggcgcttgcg
     3361 tcgccatccg gcagcgtatt gcctgatagc gctcacccgc tgtcgtgtca gggcgattat
     3421 tcaaataagt tctgatgtag cttttgcacc actttctcgg catcgtctcc cggcacgagg
     3481 aagcacagat tgtggctgga ggcgccgtaa caaatcatgc gaatgttgaa cggttccagg
     3541 acgccaaaca cttctttacc aacaccgcag gcttttgaca ggttgttgcc aatcagcgcg
     3601 accagcgcca gtccttcttc aacttcgacc cgacacagcg cggaaagctc catcaataag
     3661 gattgggtca gtaacgtatc gcccgtggag gtggagccgg tagtatccag cgtcagcgcg
     3721 acgctcacct ccgaagtggt aatcagatct accgaaatat tatgccgcgc cagaatgccg
     3781 aacacctctg ccaggaaacc tcgtgagtgc agcatattca ggctgtgcag cgtcaatagc
     3841 gtttgattgc ggcgcagcgc cagcgcgcgg aacagcggcg ggttttgggt tttattgcac
     3901 accagcgtac cgcccgcttg cggatcttta ctggagccaa cgaagaccgg gatatcgctg
     3961 cgcacggccg ggagtaaggt ggctggatgc agtacttttg cgccgaaggt tgccatctcc
     4021 gccgcttctt caaagtcgat ttcatcaatt cgctgcgcga cgggcactac gcgcgggtcg
     4081 gtggtgtaaa taccgggcac atctgtccag atatcaaccc gcgcggcgtg gagcgcttca
     4141 gccagcaacg ctgccgtata gtcgctgccg ccgcggccta atgtcgtggt gcggcctttg
     4201 ctttcactgc cgataaagcc ctgagtaatg accaacgttt cgctcaggcg cgggagcaac
     4261 tgctgcgcgg ccagttccgc aagcgctgcg acgtccggtt ccgcacgacc aaagcgatcg
     4321 ctggtacgca tcactttgcg cacgtcgaac cagtgggcct gtacgtcgcg ttcacgcagg
     4381 atctcaacaa atagcagggt agacattagc tcgccgtggc tgaccagttc atcggtcagg
     4441 gctgccgatg tcgccagcga tgccgcctcc gccagaatag tgatgttttc cagcaggcgt
     4501 tcaatctctt cgcgaatgac attcggatga cgcagacgat caaggatatc gaactggatt
     4561 ttacggatgg cgtcgagcgt agcgaaacgt tcgccgggct ccatcccttc ggccagcgcc
     4621 accagcagat tagtgatgcc ggcagacgcg gaaagcacga ctaaacgaac attggcgtcg
     4681 gaaagtacga tatccgcgct acggttcatg gcgtcaaaat cagcgacgct ggtaccgcca
     4741 aatttggaaa caacgatctc tgtcatatca acctcgtgtc aggaaatgaa aaacgcgacc
     4801 atggcacaaa ggcagaacag aaaccggtgc aggcgcaaat gcaagtaacg tatttataaa
     4861 taaaagttgt ggactggact gtcaacgttg ggattatgcg gattttttat gctgagttta
     4921 ggctcagtaa cagcgcttat aaccccgata cccgtttgta ggaatgttgg cttatctatg
     4981 cgcccggcga ctcacccact tgccgccttt ctgcacctcg aattatttag ggtatatact
     5041 ttttatcctc attcgacagt gcctggggca acggcactaa aacaatcaca cttttctgtg
     5101 actggcgtta caatcgatcc cagtcacaat tctcaaatca gaagagtatt gctaatgaaa
     5161 aacatcaatc caacgcagac ttctgcctgg caggcgctcc agaaacacta cgacgaaatg
     5221 aaagacgtta cgatcgctga gcttttcgcg aacgatagcg accgtttcgc taaattttcc
     5281 gcgacgtttg acgatctgat gctggtggac ttctccaaaa accgcatcac cgaagagacg
     5341 ctggcaaaat tacaggatct ggcgaaagag accgatctgg ccggcgcgat taaatccatg
     5401 ttctccggcg agaagatcaa ccgcaccgaa gaccgcgccg tgctgcacgt ggcgctgcgt
     5461 aaccgtagca atacgccgat cattgtggac ggcaaagatg tgatgccgga agtgaacgcc
     5521 gtgcttgaga aaatgaaaac tttctcgcaa gcgattatct ccggtcagtg gaaaggctac
     5581 accggtaagg ccatcaccga cgtggtgaac atcggtatcg gcggttccga cctcggcccg
     5641 ttcatggtga ccgaagcgct gcgtccgtat aaaaatcatc tgactatgca cttcgtctct
     5701 aacgttgatg gtacccacat cgctgaagtg ctgaaaaaag tgaacccgga aacgactctg
     5761 ttcctggtgg cgtcgaaaac cttcaccacg caggaaacca tgaccaacgc ccacagcgcg
     5821 cgcgactggt tcctgaaaag tgcaggcgat gaaaaacacg tggcgaaaca ctttgctgcg
     5881 ctctccacca acgccaaagc ggtcggcgaa tttggtatcg acacggccaa tatgttcgag
     5941 ttctgggact gggtcggcgg tcgttactcg ctgtggtctg ccatcggact gtccattatt
     6001 ctgtccgtcg gtttcgacaa ctttgtcgag ctgctttccg gcgcgcacgc gatggacaag
     6061 catttctcca ccactccggc ggagaaaaac ctacccattc tgctggcgtt gattggcatc
     6121 tggtacaaca atttcttcgg cgcggaaacc gaagccattc tgccgtacga ccagtatatg
     6181 caccgtttcg ccgcctactt ccagcagggc aacatggaat ccaacggtaa atacgttgac
     6241 cgtaacggca acgccgtgga ttaccagaca ggcccaatta tctggggcga accaggcacc
     6301 aacggtcagc acgcgtttta tcaattgatt caccagggta ctaaaatggt gccgtgtgac
     6361 tttatcgccc cggctatcac ccataacccg ctatccgatc atcatcagaa gctgctgtct
     6421 aacttcttcg cgcagaccga agcgctggcg tttggtaaat cccgcgaggt ggttgagcag
     6481 gaatatcgcg atcagggtaa agatccggcg cagcttgaac acgttgtgcc attcaaagtg
     6541 tttgaaggca accgcccgac caactctata ctgctgcgcg aaattacgcc gttcagcctg
     6601 ggcgcgctga ttgcgttgta tgagcataaa atctttacgc agggcgtcat cctgaacatc
     6661 tttactttcg accagtgggg cgttgagttg ggtaaacagt tggctaaccg tattctgccg
     6721 gagctgggcg atgataaagc tatttcgtcc catgatagct ctactaacgg tctgattaac
     6781 cgttataaag cctggcgcgc ctgatggcgc tgcgcttatc cggtctacgt aatgcatagc
     6841 gtctgtaggc cggataaggc gtttcgccgc catccggcaa aaagagaata agataataaa
     6901 aaggccgata ttcacatcgg ctttttttat aagataattc cgcttg
//
LOCUS       DAJVBX010000218         6921 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.218, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000218 DAJVBX010000000
VERSION     DAJVBX010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 6921)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6921)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6921
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.218"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..328
                     /locus_tag="OPV72_003953"
     CDS             <1..328
                     /locus_tag="OPV72_003953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="CZB domain-containing protein"
                     /protein_id="HCR9916123.1"
                     /translation="DHVIWKMEVYKLLLNKDINSKITMHDQCRLGKWYYGFEGQQFSN
                     YYSFRSLEAPHKEVHTAGHSALNYFAAGDMNAMSQELDRMERSSNEVVNQLEMLAVDL
                     LKETTV"
     gene            complement(628..2040)
                     /gene="uxaC"
                     /locus_tag="OPV72_003954"
     CDS             complement(628..2040)
                     /gene="uxaC"
                     /locus_tag="OPV72_003954"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HCR9916124.1"
                     /translation="MATFMTEDFLLKNDIARTLYHKYAAPMPIYDFHCHLSPQEIADD
                     RRFDNLGQIWLEGDHYKWRALRSAGVDESLITGKETSDYEKYMAWANTVPKTLGNPLY
                     HWTHLELRRPFGITGTLFGPDTAESIWTQCNEKLATPAFSARGIMQQMNVRMVGTTDD
                     PIDSLEYHHQIAADDSIDIEVAPSWRPDKVFKIELDGFVDYLGKLEAAADVSITRFDD
                     LRQALTRRLDHFAACGCRASDHGIETLRFAPVPDDAQLDAILGKRLAGETLSELEIAQ
                     FTTAVLVWLGRQYAARGWVMQLHIGAIRNNNTRMFRLLGPDTGFDSIGDNNISWALSR
                     LLDSMDVTNELPKTILYCLNPRDNEVLATMIGNFQGPGIAGKVQFGSGWWFNDQKDGM
                     LRQLEQLSQMGLLSQFVGMLTDSRSFLSYTRHEYFRRILCNLLGQWAQDGEIPDDEAM
                     LSRMVQDICFNNAQRYFTIK"
     gene            complement(2052..3524)
                     /locus_tag="OPV72_003955"
     CDS             complement(2052..3524)
                     /locus_tag="OPV72_003955"
                     /EC_number="1.1.1.57"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructuronate reductase"
                     /protein_id="HCR9916125.1"
                     /translation="MEQNIATAQVSVARPNWDKSRLVSRIVHLGCGAFHRAHQALFTH
                     HLLEKSDSDWGICEVNLMPGNDARLIANLKAQNLLYTVAERGAESTELKIIGSMKEAL
                     HPEFDGHAGILAAMARPETAIVSLTVTEKGYCTDPASGELDVNNPLIQNDLAHPQQPK
                     SAIGYIVEALNMRREQGLKAFTVLSCDNVRENGHVAKAAVLGLAKARDAALAAWIADN
                     VTFPCTMVDRIVPAATEETLQLVADQLGVYDPCAIACEPFRQWVIEDNFVNGRPDWDT
                     VGAQFVADVVPFEMMKLRMLNGSHSFLAYLGYLGGYDTIADTMTNPAYRRAALALMLD
                     EQAPTLSMPEGTDLEGYANLLIARFTNPSLKHRTWQIAMDGSQKLPQRLLDPVRLHLQ
                     QGDDYRRLTLGVAGWMRYVGGVDEQGKTIDVVDPLLAQYQAIHQQYQTPEERVRGLLA
                     IESIFGNDLPKNHEFVQAVTDAYQQLLQNGAKATVEALAK"
     gene            complement(3635..4819)
                     /gene="uxuA"
                     /locus_tag="OPV72_003956"
     CDS             complement(3635..4819)
                     /gene="uxuA"
                     /locus_tag="OPV72_003956"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HCR9916126.1"
                     /translation="MKQTWRWYGPNDPVTLSDVRQAGATGVVTALHHIPNGEIWSVDE
                     IQKRKAIVEEAGLEWSVVESVPIHEDIKTHTGQYDLWIKNYQQTLRNLAQCGIYTVCY
                     NFMPVLDWTRTDLEYVLPDGSKALRFDQIEFAAFELHILKRPGAEADYTAEEIAQAER
                     RFATMSEEDKARLTRNIIAGLPGAEEGYTLDQFRQHLATYKDIDKAKLREHFAYFLKA
                     IIPVADEVGVRMAVHPDDPPRPILGLPRIVSTIEDMQWMVETVNSMANGFTMCTGSYG
                     VRADNDLVDMIKQFGPRIYFTHLRSTLREENPKTFHEAAHLHGDVDMYEVVKAIVEEE
                     HRRKAEGSDDLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGVELAIQRAFF
                     SK"
     gene            5224..6528
                     /locus_tag="OPV72_003957"
     CDS             5224..6528
                     /locus_tag="OPV72_003957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR9916127.1"
                     /translation="MKMTKLRWWIIGLVCVGTIVNYLSRSSLSVAAPAMMKELHFDEQ
                     QYSWVVSAFQLCYTIAQPITGYLMDVIGLKIGFFIFALLWSLINMAHALAGGWISLAF
                     LRGLMGLTEASAIPAGIKASAEWFPTKERGIAGGLFNIGTSIGAMLAPPLVVWAMLTF
                     ADSGIGTEMAFVITGGIGVLFAITWFLIYNSPNKHPWITHKELRYIEDGQESYLQDDN
                     KKPAVKEIVKKRNFWALAITRFLADPAWGTLSFWMPLYLINVMHLPLKEIAMFAWLPF
                     LAADFGCVAGGFLAKFFMEKMHMTTINARRCSFTIGAVLMISIGFVSITTNPYVAIAL
                     MSIGGFAHQTLSTVVITMSADLFKKNEVATVAGLAGSAAWMGQLSFNLFMGALVAIIG
                     YGPFFIALSLFDIIGAIILWVLIKDPEKHHPPMTEQPLASHR"
BASE COUNT         1570 a         1774 c         1796 g         1781 t
ORIGIN      
        1 tgaccatgtt atctggaaaa tggaagtcta caaattactc ttaaataaag acataaacag
       61 taaaataacg atgcacgatc agtgtcggct ggggaaatgg tactacggtt ttgaagggca
      121 gcagtttagc aattactaca gtttccgtag tctggaagcg ccgcataaag aggtgcatac
      181 cgctggtcac tctgcgctga actattttgc cgcaggcgat atgaatgcga tgtcgcaaga
      241 actcgacaga atggagcgat ccagtaatga ggtggttaac cagctggaaa tgctggctgt
      301 cgatttgtta aaagaaacca cagtgtgaag tcatgagtta ttaccgtata accaacagga
      361 gccatcatca acaggactga tgtatcacac tttctgcact ggagttattc cggacagaga
      421 aaaaaagcat gacgcagaag atggctgtgt ttgtttaccc gaatcactta ccttagtaag
      481 tgattcggga ttaatcagca acctctttgc tttttatcgg tggccagact ttggctggaa
      541 aagtgcgtta ctgctaaatt tctcactctc ttaccgcctt cctgcccctc gaaatacctg
      601 aaacctgtgc tcacagatta atagcgatta tttaatcgtg aaataacgct gggcattatt
      661 gaagcagata tcctgaacca tacggcttaa catcgcttca tcatcaggaa tctctccgtc
      721 ctgcgcccac tgtcccagca ggttacagag aatacgccgg aaatattcat gtcgcgtata
      781 agaaaggaaa ctgcgggagt cggtcagcat cccgacaaac tgacttaaca gtcccatttg
      841 cgacagttgc tccagttggc gcagcatccc gtctttctga tcgttaaacc accagccgga
      901 accaaactgc acttttccgg caattcccgg cccctggaag ttaccgatca tggtcgccag
      961 gacttcgtta tcacgtgggt tcaggcaata gaggatagtc ttgggcagtt cattggtcac
     1021 atccatactg tcgagcaaac gggagagcgc ccagctaatg ttattatcgc caatagagtc
     1081 aaagccggta tccggcccga gcaggcggaa catacgggta ttattgttac ggatcgcgcc
     1141 aatatgtagc tgcatcaccc agccgcgcgc ggcgtactga cggcccagcc agaccagcac
     1201 cgccgtggta aactgggcga tctcaagttc gctcaacgtt tcgcctgcca gacgtttgcc
     1261 cagaatggcg tcaagctgcg cgtcgtcggg caccggcgca aatcgcagcg tttcaatgcc
     1321 atgatcggac gcgcggcagc cgcaggcggc gaaatggtcg aggcggcgag tgagcgcctg
     1381 acgtaaatcg tcgaaacggg taatgctgac atctgccgcc gcttccagtt tccccaggta
     1441 atcgacaaag ccgtccagtt cgattttgaa aactttgtcg gggcgccagc ttggcgcgac
     1501 ttcaatatca atgctgtcgt cggcggctat ctggtggtga tattccagag aatctatagg
     1561 gtcgtcggtg gttccgacca tccgcacatt catctgctgc ataataccgc gcgcggaaaa
     1621 ggccggcgtc gccagtttct cattacactg cgtccagata ctttccgcgg tatccggtcc
     1681 gaacagcgta cctgtaatgc caaatggacg gcgtagttca aggtgcgtcc agtgatacag
     1741 cggattgccc agcgtttttg gaacggtatt ggcccaggcc atatattttt cataatcgct
     1801 ggtctctttg ccggtgatca gcgactcatc cacgcctgcg cttcgtagcg ctcgccattt
     1861 atagtggtcg ccttccagcc agatctgacc gaggttatcg aaacggcgat cgtcggcgat
     1921 ttcctgcgga cttaaatggc agtggaagtc ataaatcggc atgggcgcgg cgtatttatg
     1981 gtacagcgtg cgggcaatgt cgtttttaag tagaaaatct tcagtcataa acgtagccat
     2041 gatttatctc cttacttagc cagcgcttct accgtggctt tcgcgccatt ctgcaatagc
     2101 tgttggtaag cgtcggtaac ggcttgcaca aattcgtggt tcttcggcag gtcgttgcca
     2161 aagatagact cgatggccag tagcccgcga acgcgttctt ccggcgtctg atattgctga
     2221 tgaatcgcct gatactgtgc aagcagcgga tcgacgacat caatggtttt accttgctca
     2281 tcgacaccgc cgacataacg catccatccg gcgacgccca gcgtcaggcg gcgatagtca
     2341 tcgccctgtt gcaagtgcag acgtaccggg tccaacagac gctgcggcag tttctgactg
     2401 ccatccatcg cgatctgcca ggtgcggtgt ttcaacgagg ggttagtgaa acgcgcaatc
     2461 aacaaattcg catacccttc cagatcggtg ccttccggca ttgacaacgt cggcgcttgt
     2521 tcatcaagca tcagcgccag cgccgcgcga cggtaagccg ggttagtcat agtatcggcg
     2581 atagtgtcat acccgccgag ataacccaga taggcgagga aagagtgact gccgttaagc
     2641 atacgcagct tcatcatctc aaacggtacg acatctgcaa cgaattgcgc gccgacggta
     2701 tcccagtccg ggcgaccatt cacaaagtta tcttcgatga cccactggcg gaagggttcg
     2761 caggcgatag cgcaaggatc ataaacgccc aactggtcgg caaccagttg tagcgtctct
     2821 tcggtcgctg ccggaacaat gcggtcaacc atggtgcagg ggaaggtcac attgtcggca
     2881 atccatgcgg cgagggcggc atcgcgagct tttgccaggc cgaggacggc agccttcgcg
     2941 acgtgaccat tctcgcgcac gttatcgcac gacagcacgg taaaagcttt cagtccttgc
     3001 tcccggcgca tgtttagcgc ttcgacaata tagccaatgg cggatttagg ctgctgtgga
     3061 tgggcaagat cgttttggat cagcgggtta ttgacatcaa gctcgccgct ggcggggtcg
     3121 gtgcagtagc ctttttcggt tacggttaag gagacgatgg cggtttccgg gcgcgccatt
     3181 gccgccagaa tccctgcatg accgtcgaat tcagggtgta gcgcttcttt cattgaaccg
     3241 ataattttca gttcggtgct ttctgcgccg cgttctgcaa cggtgtacag cagattttgc
     3301 gctttcaggt tcgcgatcag ccgcgcgtcg ttacccggca tcaggttcac ttcacaaatg
     3361 ccccagtcgc tgtcgctctt ttccagtaga tgatgggtaa agagcgcctg gtgcgcgcgg
     3421 tgaaacgccc cgcagcccag atgcacaata cgggatacca gacgtgattt gtcccagttt
     3481 gggcgggcga cggaaacctg ggcggtggcg atattctgtt ccattgcaaa ctcctgtcat
     3541 tcgacgtctt cgcccgcgat ctccggggcg aggcatgttg ctattgcatt gagtagggga
     3601 aatcgcatga cgcgtcgcgc catgcgaaag aaggttattt gctaaagaaa gcgcgctgga
     3661 tagccagttc gacgccgcgg acttccgcaa gccctttcag acggccaatg gcggaataac
     3721 ccggattcgt tttcttcttc agatcgtcca gcatctgatg accgtggtcc gggcgcattg
     3781 ggatcagatc gtcgctacct tcggctttac gacggtgctc ttcttccaca atcgctttaa
     3841 cgacttcata catatccaca tcgccgtgca aatgggcggc ctcgtggaag gtctttggat
     3901 tctcttcgcg cagcgtagag cgcagatgcg taaagtagat gcgcggacca aattgcttga
     3961 tcatatcaac cagatcgttg tcggcgcgca cgccgtaaga tccggtacac atggtgaagc
     4021 cgttcgccat gctattaacg gtttcaacca tccattgcat gtcttcaatg gtagagacaa
     4081 tgcgcggcag gccgagaata gggcgcggcg gatcgtcagg gtgaacggcc atacgcacgc
     4141 caacctcgtc ggcaaccgga ataatggctt tcaggaaata ggcaaaatgt tcacgcagtt
     4201 ttgctttatc gatatcttta tacgtcgcca ggtgttgacg gaactgatcc agcgtatagc
     4261 cttcttccgc gccaggtaaa ccggcaataa tgttgcgggt cagacgtgct ttgtcttcct
     4321 cgctcatggt ggcgaaacgc cgctctgcct gagcaatctc ttctgccgta tagtcggctt
     4381 ctgctcccgg acgcttcagg atgtgcagtt cgaacgcggc gaattcaatc tggtcaaaac
     4441 gcagcgcttt tgaaccatcc ggcaatacgt attccagatc cgtacgtgtc cagtccagca
     4501 ccggcataaa gttatagcaa accgtataga taccgcattg cgccaggtta cgcagcgttt
     4561 gctggtagtt tttgatccat aaatcgtact gaccggtgtg ggttttgatg tcttcgtgga
     4621 taggtacgct ctctaccaca gaccactcca gacccgcctc ttcaacgatt gctttacgtt
     4681 tctggatctc gtctaccgac caaatttctc cattcggaat atggtgtaac gccgttacca
     4741 cgccggttgc gccagcctgg cgtacatctg acagcgttac cgggtcgtta ggtccgtacc
     4801 agcgccaggt ttgtttcata tctcgtttcc tcttcttgcg ataacgtctt cgtggttgac
     4861 ccattgccag ccaacatcga aacgtgcttt gtaaacccgt tctgccccct aaattcaacc
     4921 aaaatttttc tcatgtcaac cttattatct aaattggcta gccaaatcac aaatatcatc
     4981 attcacggtc tgccaatttt atttatttga tctgcgtcaa tttttgctgg gtgaaaagca
     5041 ttcaccattc aacttgaaat gagttgatgt atttatttca agaatattaa gggcgggagt
     5101 tgccgccaga ttttgaccgg tccggatgag aaaatattga ttggtcaacc aatttttgta
     5161 atttcagttt tcccgctaca ggtcagacgg cgcggagcta atgtttttta acgaggcttt
     5221 atcatgaaga tgacaaaatt aagatggtgg attatcggcc tggtctgcgt ggggaccatc
     5281 gtaaactacc tgtcccgtag ctcgcttagc gttgcggcgc cagcgatgat gaaagaactc
     5341 cattttgatg agcaacaata ttcctgggtg gtgagcgcct tccagctttg ttacaccatt
     5401 gcgcagccga tcaccggcta tttgatggat gtcatcggac tgaaaatcgg cttctttatc
     5461 tttgccttgt tgtggtcgct gatcaacatg gcgcacgcgc tggccggcgg ctggataagc
     5521 ctggcatttc tgcgtggtct gatggggcta accgaagcgt cagcgattcc ggccgggatt
     5581 aaagccagcg ccgaatggtt cccgacgaaa gaacgtggta ttgcgggggg cctgtttaat
     5641 atcggtactt caattggcgc gatgctggcg ccgccgctgg tggtctgggc gatgctgacc
     5701 tttgctgata gcggcatcgg tactgaaatg gcgtttgtga ttaccggtgg gatcggcgtg
     5761 ctgttcgcca tcacctggtt cctgatttat aactcgccaa ataaacaccc gtggatcacc
     5821 cacaaagagc tgcgttatat cgaagacggc caggaaagct atctccagga cgataataaa
     5881 aaaccggccg ttaaagagat cgttaaaaag cgtaacttct gggcgttggc gattacccgt
     5941 tttcttgctg acccggcatg gggaacgctg agtttctgga tgccgctgta tctgattaac
     6001 gtgatgcatc tgccgttaaa agagatcgcc atgtttgcct ggctgccgtt cctggcggcg
     6061 gacttcggct gcgttgcagg cggtttcctg gcgaagttct tcatggaaaa gatgcacatg
     6121 accacgatca atgcgcgtcg ttgtagcttt accatcggcg ctgttttgat gatttcgatc
     6181 ggttttgtca gcattacgac taacccgtat gtcgccattg cattgatgag tattggcggt
     6241 tttgcgcacc agacgctgtc taccgttgtg attaccatga gcgctgacct gttcaagaaa
     6301 aatgaggtcg cgacggttgc cggtctggca ggatctgcgg catggatggg acagttaagc
     6361 ttcaacctgt ttatgggggc attggtcgct attatcggtt acggcccgtt cttcattgca
     6421 ctcagtctgt tcgatattat cggcgccatc atcctgtggg tactgattaa agatccggaa
     6481 aagcaccacc cgccaatgac ggaacagccg ctggcgtctc accgctaaag ctgtctcggt
     6541 ttcacaggcc tgataagcga agcgctaccg ggttctaacg gccaccttcg ggtggccgtc
     6601 ttcattaccc ttatcggtaa aaatacgcgt tggttttata ccagcgcgtt atcatttagt
     6661 ttgcctgatt attttcagat gctgaaaata atattgtggt aagggttatt gtttttcgcc
     6721 tggattttta tcgactctct gtctcgctgc gatcatcgat aaagtcccct ttatgtaaat
     6781 aaaggttcaa tgcttctact cttttctcca tatattttgc gcagcttcac aaaaaataac
     6841 ctgatgtcgt aatgtccact ccctaatatt ctccatgcgc tatacgttaa tttaagttta
     6901 aatttcatgc tggggatatc a
//
LOCUS       DAJVBX010000219         6878 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.219, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000219 DAJVBX010000000
VERSION     DAJVBX010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 6878)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6878)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6878
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.219"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            129..899
                     /locus_tag="OPV72_003958"
     CDS             129..899
                     /locus_tag="OPV72_003958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein FixA"
                     /protein_id="HCR9916128.1"
                     /translation="MKIITCYKCVPDEQDIAINNADGTLDFSKADSKISQYDLNAIEA
                     ACQLKQQLGDAQVVAMSVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQHTAT
                     ALAAAAQKSGFDLLICGDGSSDLYAQQVGLLVGEALNIPAINGVSKILSLTDSTLTVE
                     RELEDEVETLSIPLPAVIAVSTDINTPQIPSMKAILGAAKKPVQVWSPADIGLNSVPA
                     YSTQQVAAPKQRERQRVVIEGDGEEQIAAFVENLRKII"
     gene            915..1856
                     /locus_tag="OPV72_003959"
     CDS             915..1856
                     /locus_tag="OPV72_003959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HCR9916129.1"
                     /translation="MNKFSSVWVFSDTPSRLPELMSGAQAVGEKVNAFVLNEADSATA
                     CHLGADHVWLLSGKPEDRMIEDYAAAMAETIRQHSEGGAVLLPNTRRGKLLAAKLGYR
                     LSAAVSNDASDVSLQDGKAAVKHMVYGGLAIGAETIASPFAVITLSSGTFDAQQPDAS
                     RSGEMHTVQWQAPATAVTRTATQARQSNSVDLDKARLVVSVGRGIGSKENISLAEALC
                     QTIGAELACSRPVAENEKWMEHERYVGISNLMLKPELYLAVGISGQIQHMVGANGAQT
                     IFAINKDKNAPIFQYADFGIVGDALKILPALTAALAR"
     gene            1906..3192
                     /locus_tag="OPV72_003960"
     CDS             1906..3192
                     /locus_tag="OPV72_003960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HCR9916130.1"
                     /translation="MSEDIFDAIIVGAGLAGSVAALVLAREGAQVLVIERGNSAGAKN
                     VTGGRLYAHSLERIIPGFADQAPIERMITHEKLAFMTDNGAMTIDYCNGEDASASQVS
                     YSVLRSKFDAWLMEQAEEAGAQLITGIRVDNVVQRDGKVVGVEADGDILEAKVVILAD
                     GVNSLLAEKLGMAKRVEASHVAVGVKELIELPKSVIEDRFQLQGNEGAACLFAGAPTD
                     GLMGGGFLYTNETTLSLGLVCGLHHLKDAKKSVPQMLEDFKQHPAVAPLIAGGKLVEY
                     AAHVVPEAGMNMQPELVGDGVLIAGDAAGMCMNLGFTIRGMDLAISAGEAAAKTVLSA
                     MKRDDFSKQSLGEYRQHLDEGPMRDMRMYQKLPAFLDNPRMFTAYPEMAVSIARDLFT
                     VDGSAPVPMRKKILRHAKKVGFINLMKDGLKGVTVL"
     gene            3189..3476
                     /gene="fixX"
                     /locus_tag="OPV72_003961"
     CDS             3189..3476
                     /gene="fixX"
                     /locus_tag="OPV72_003961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-like protein FixX"
                     /protein_id="HCR9916131.1"
                     /translation="MTSPVNVDVKLGVNKFNVDEDSPHIILKTDPDKQALEVLVKACP
                     AGLYKKQDDGSVRFDYAGCLECGTCRILGLDTALEKWEYPRGTFGVEFRYG"
     gene            3624..4964
                     /locus_tag="OPV72_003962"
     CDS             3624..4964
                     /locus_tag="OPV72_003962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR9916132.1"
                     /translation="MPQPRNFDDLKFSSIHRRIMLWGSGGPFLDGYVLVIIGVALEQL
                     TPLLHLDAEWIGALGAATLAGLFIGTSLFGYICDKVGRRKMFLLDIIAIGVISVATMF
                     VSTPLELLVMRVLIGIVIGADYPIATSMITEFSNTRQRAFSIGFIAAMWYVGATCANL
                     VGYWLYDMEGGWRWMLGSAFIPCLIILIGRFDLPESPRWLLRKGRVKECEQMMIKLFG
                     EPVCFDDEPPQETRFLQLFNRRHFPFVLFVAAIWSCQVIPMFAIYTFGPQIVGLLGWE
                     QGRNAALGNVVISLFFMLGCIPAMFWLNSIGRRPLLIGSFAMMTIALALLGLVSNLGI
                     ILVVVAFAVYAFFSGGPGILQWLYPNELFPTDIRASAVGVIMSLSRIGTIVSTWALPI
                     FITRYGINNVMLIGALISLVGLGVSVMFAPETRGLTLTQTGNMTLRGTPSDNPR"
     gene            5053..5283
                     /locus_tag="OPV72_003963"
     CDS             5053..5283
                     /locus_tag="OPV72_003963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgdI/YgdR family lipoprotein"
                     /protein_id="HCR9916133.1"
                     /translation="MQKRLMTALFTAATLFTVAGCSSNQAVETTDGKTIVTDGKPEVD
                     NDTGMVSYKNAATGKTEQINRDQLKNMSELDN"
     gene            5574..5990
                     /locus_tag="OPV72_003964"
     CDS             5574..5990
                     /locus_tag="OPV72_003964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916134.1"
                     /translation="MKLIPFYLLALFSAASGATEINACKDLIGTWKTTADNPPYTMTI
                     LPPVEGCGEKCVKLNVQYELDVTHRNALYCHEGQEGVKGQGPMVIAFEGAYGGHAIGT
                     YNRQLQLLWAGVIPKNKKGKWITKMENYWFRQVKAH"
     gene            complement(6214..6504)
                     /locus_tag="OPV72_003965"
     CDS             complement(6214..6504)
                     /locus_tag="OPV72_003965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HCR9916135.1"
                     /translation="MKKRIIAAALLATVASFSTLAAEQVSKQEISHFKLVKVGTINVS
                     QSGGQISSPSDLREKLSELADAKGGKYYHIIAAREHGPNFEAVAEVYNDATK"
BASE COUNT         1590 a         1724 c         1885 g         1679 t
ORIGIN      
        1 ttacgaatat caatgtgtga cattttcaat attggtgatt aaggttttat ttccgaatta
       61 aagagcgtga tatctgtatt taacaccgcc gatataaata cgtttccttc atgatttctg
      121 gagatgcaat gaagataatt acttgctaca aatgcgtacc tgatgagcag gatattgcga
      181 ttaataatgc tgacggaaca ctcgatttca gcaaagcgga tagcaaaatc agccaatatg
      241 atctgaatgc aattgaagct gcttgccagt taaaacagca gttgggagac gctcaggttg
      301 tcgccatgag cgttggcggc aaagcgctga ctaatgcaaa agggcgcaaa gatgtcctct
      361 ctcgtggccc tgatgaactg attgtggtca ttgacgatca atttgagcag gcgctgccgc
      421 aacacaccgc taccgcgctg gccgccgcgg cgcaaaaatc aggtttcgat ctacttatct
      481 gcggcgacgg ttcttccgat ctttatgctc agcaggttgg tttgctggtg ggcgaagcgc
      541 tgaacattcc ggcgattaac ggcgtgagta aaatcctctc tcttaccgac agcacattga
      601 cggtagaacg cgaactggaa gatgaagttg aaacgctgag catcccgctc ccggcggtga
      661 tcgcggtttc caccgacatt aacaccccac aaatcccttc gatgaaagcc attcttggcg
      721 cggcgaaaaa accggttcag gtctggtcgc ctgcggatat cgggctgaac agcgtacccg
      781 cgtattccac acaacaggtt gccgcaccga agcagcgcga gcgtcagcgt gtggtgattg
      841 aaggtgacgg tgaagaacaa atcgccgcgt ttgtcgagaa tctgcgcaaa atcatttaat
      901 tatcagggga tgttatgaac aaattttcca gtgtctgggt attcagcgat accccttctc
      961 gtctgcccga actgatgagt ggtgcgcagg ctgtaggtga aaaagttaac gcgttcgtac
     1021 tgaacgaagc ggacagcgcg acagcatgtc atttgggcgc ggatcatgtc tggctgctca
     1081 gcggcaaacc agaagatcgc atgatcgaag actacgctgc tgcgatggct gagactattc
     1141 gtcagcatag cgagggcggc gcggtgctgc tgccgaatac gcgtcggggc aagctgttgg
     1201 cggcaaaact gggctatcgc ttgtcggctg cggtttccaa cgacgccagc gacgtctccc
     1261 tgcaggatgg aaaagcggcg gtcaaacata tggtctacgg cggtctggcg ataggggcag
     1321 agaccatcgc ttcgccgttt gccgtgatca cactcagcag cggaacgttt gacgcacaac
     1381 agccggatgc ttctcgcagc ggcgagatgc acaccgtgca gtggcaggct ccggccactg
     1441 ccgtgacccg caccgcaacc caggcgcgtc agagcaacag cgttgacctc gacaaagcgc
     1501 gtctggtggt cagcgtggga cgcggcatcg gcagcaaaga gaatatctcg ctggccgaag
     1561 cgctgtgcca gaccatcggc gccgagctgg cctgttcccg cccggtggcg gaaaacgaga
     1621 agtggatgga gcacgagcgc tacgtcggta tctccaacct gatgctcaaa cctgaactgt
     1681 atctggcggt ggggatctcc gggcagatcc aacacatggt cggcgccaac ggcgcgcaga
     1741 cgattttcgc catcaacaaa gataaaaacg cgccaatctt ccagtatgcg gattttggca
     1801 tcgttggcga tgcgctgaag atcctgcctg cgctgacggc tgccttagcg cgataaacca
     1861 tttcgggcag gatacgaagg tatcctgccg ctgacaggag tacgtatgtc cgaagatatc
     1921 tttgatgcca tcatcgtggg tgcaggtctg gccggttcgg ttgcggcgct ggtgcttgct
     1981 cgcgaaggtg cacaggtgct ggttatcgag cgcggcaatt ctgctggcgc gaagaatgtc
     2041 accggtgggc gtttgtatgc acatagcctg gaacgcatca ttcccggctt tgcggatcag
     2101 gcccccattg aacgcatgat cacccacgaa aaactcgcct ttatgaccga caacggggcg
     2161 atgactatcg actactgcaa tggtgaagat gcttcagcgt cgcaggtttc ttattccgtt
     2221 ttgcgtagta aatttgacgc ctggctgatg gagcaggccg aagaggcggg ggcgcaactg
     2281 atcactggta ttcgcgtgga taacgttgtt cagcgtgatg gcaaagtcgt gggcgtggaa
     2341 gccgatggcg atattctgga agccaaagtc gtaatcctcg ctgacggggt gaattctctg
     2401 ctggctgaaa agctgggcat ggccaagcgt gttgaggcat cgcatgttgc cgtcggtgtg
     2461 aaggaactga tcgaattgcc gaagtcggtc attgaagatc gtttccagct acagggcaac
     2521 gaaggtgccg cctgtctgtt tgccggggcg ccaaccgatg gtctgatggg cggtggcttc
     2581 ctgtatacga atgaaacaac cctttcccta gggctggtct gcggtcttca tcatctgaaa
     2641 gacgcgaaaa aatcggtccc gcaaatgctg gaagatttca aacagcatcc ggccgttgcg
     2701 ccgctgatcg ccggtggcaa gctggtggaa tatgccgcac acgttgtacc cgaggcggga
     2761 atgaatatgc agcctgaact ggtgggcgat ggtgtactga ttgccggaga cgctgccggc
     2821 atgtgtatga acctcggctt taccatccgg ggtatggatc tcgccatatc cgcaggcgaa
     2881 gcggcggcga agacggtgct ttcggcgatg aagcgcgacg attttagcaa gcagtcgttg
     2941 ggtgaatacc gtcagcatct ggacgaaggt ccgatgcgcg atatgcgcat gtatcagaaa
     3001 ctgccagctt ttcttgataa tccccgcatg tttaccgcct atcccgaaat ggcggtcagt
     3061 atcgcgcgcg acctgttcac cgtggatggc tccgcgccgg tgcccatgcg taaaaaaatc
     3121 ctgcgccatg cgaagaaagt gggcttcatc aacctgatga aagatggcct gaaaggagtg
     3181 accgtattat gacatctccc gtcaatgtgg acgtcaaatt gggcgtcaat aagttcaatg
     3241 tggatgaaga tagcccgcac atcattctca aaaccgatcc tgataaacag gcgctggagg
     3301 tgctggttaa ggcctgtccg gcgggactgt ataaaaagca ggacgacggt agcgttcgtt
     3361 ttgattacgc cgggtgcctg gagtgcggaa catgccggat cctcggcctt gatacggcgc
     3421 tggaaaaatg ggaataccca cgcgggacgt ttggcgtgga gttccgctac ggctaataag
     3481 tacgagtttg tgcccccgta ggccggatta gatgcggtag cgtcgccatc cggcaatcat
     3541 gtggcgccaa tgccggatgg cggcgtaaac gccttatccg gcctacagat gacgctttgc
     3601 ccgtgttgaa acaggacatc accatgccgc agcccaggaa ctttgacgac cttaaattct
     3661 cctccatcca tcgcagaatt atgctgtggg gaagcggcgg cccgttcctt gatggctacg
     3721 tgctggtgat cattggcgtg gcgctggaac aactgacgcc gctattgcac cttgatgctg
     3781 aatggattgg cgcgctcggc gcggctacgc ttgccggact gtttatcggc acctcgttgt
     3841 ttggctatat ttgcgataaa gtcgggcggc gtaaaatgtt cctgcttgat attatcgcta
     3901 tcggcgttat ctccgtggcg accatgtttg tttccacgcc gcttgaattg ctggtgatgc
     3961 gcgttttaat tggcattgtt atcggcgcgg attaccctat cgccacttcc atgattacgg
     4021 agttttccaa cacccgccag cgtgcgttct ccatcggttt tatcgccgcg atgtggtacg
     4081 tcggcgcgac ctgcgccaac ctggtgggtt actggctgta tgacatggaa ggaggctggc
     4141 gctggatgct tggcagcgcc tttatcccgt gcttaatcat tttgattggc cgctttgacc
     4201 tgccggaatc gccacgctgg ctattgcgaa aaggacgggt aaaagagtgc gaacaaatga
     4261 tgatcaaact gttcggcgaa ccggtctgct ttgacgatga gccgccgcag gagacccgct
     4321 tcctgcagct gtttaaccgc cgtcatttcc cgtttgtact gttcgttgcg gctatctgga
     4381 gctgtcaggt gatcccgatg ttcgctatct atacctttgg gccgcagatc gtcgggttac
     4441 tcggctggga acaggggcgc aacgcggcgc tcggcaatgt ggtgattagc ctctttttta
     4501 tgctgggctg tataccggcg atgttctggc taaacagtat tggccgtcgc cctctgctta
     4561 ttggcagctt cgccatgatg actatcgcgc tggcgctgct ggggctggtg tcaaatctgg
     4621 gtatcatact ggtcgtggtg gcgtttgcgg tatacgcctt cttttccggc ggaccgggca
     4681 tactgcaatg gctttatcct aatgaactct tccctacgga tattcgcgct tcggccgtgg
     4741 gggtcatcat gtcattaagc cgtatcggaa ccattgtctc cacctgggca ttaccgattt
     4801 ttattactcg ttacggtatt aataacgtca tgctgattgg cgcgttgatt tcgttagtcg
     4861 ggcttggcgt atcggtgatg tttgccccgg aaactcgcgg cttgacgcta acacagaccg
     4921 gaaacatgac tttgcgcgga acgccatcgg ataaccctcg ttaagagtgt tctgcatttc
     4981 tccctgcttt tcgccaataa cgctacagtt aacagtcaca tgctaaaaca actgaaaagc
     5041 agggagaaca ccatgcaaaa acgtcttatg accgcactgt ttaccgcagc aacactattc
     5101 accgtcgcag gatgctcttc taaccaggcg gttgaaacca cggatggcaa aactattgtc
     5161 accgacggga aacccgaggt cgataacgat accggtatgg tgtcttacaa aaacgccgcc
     5221 accgggaaaa ccgaacagat taaccgcgat cagctgaaaa atatgagcga gctggataat
     5281 taattcaatt ttttctggtt agccgcgcaa taatattctc tctttatgcg catccattta
     5341 ttcccatgcg aataaacgga tgcctgaact ggcagggacg ccggaaaacg tcgaaatacg
     5401 ttcgcccgtg ttcccgcttt ccccaccgcg ctgtccgctt acatgaggtt acactcatcg
     5461 acatttctct gaacagcggc tcaacatttc ccggaaaaaa catatcgcaa ggcatttatc
     5521 cttatgatta ggtataaatg attaggtata aggaaacgga gtctgtaatg aaactgaaac
     5581 taataccttt ttatttgctc gcgctatttt ctgccgcctc cggggctacg gagataaacg
     5641 cctgcaaaga cctgatcgga acatggaaaa ccactgcaga taacccgcct tataccatga
     5701 caatattgcc gccagtagaa ggctgcgggg aaaaatgtgt gaaactgaac gtacagtatg
     5761 aacttgacgt gactcaccgc aacgcgcttt attgccatga aggacaagag ggggtaaaag
     5821 ggcagggacc catggtgata gcatttgaag gggcgtatgg tggacacgct attggaacct
     5881 ataaccgaca gctgcaatta ctttgggctg gcgtaatacc gaaaaataaa aaggggaaat
     5941 ggataacgaa aatggaaaat tactggttca ggcaggtaaa agcgcactaa atattacctt
     6001 aaaacagccc gcaaaaccgt cttattcacg aagggcttac tgcctgcgcg cgcacattcc
     6061 aacggcttgc ctgccccgga tgaactgttg ataaaaaaga gggccagcat ctgtttccag
     6121 acggccctga gtggattgtg acgtaacatg gcaccttgct ggcgctctct tattatttca
     6181 tgccagtgcc atcgttatgg cgcaatcaga gctttatttc gtcgcatcgt tataaacttc
     6241 ggcaacggct tcaaaattcg gaccatgctc acgtgcagcg ataatatggt aatattttcc
     6301 gcctttcgca tcggctaatt ctgacagttt ttcgcgtaga tcagagggtg aggaaatctg
     6361 cccgccactc tgggacacat ttatggtgcc gaccttaacc agtttgaagt ggctgatttc
     6421 ttgcttagag acctgctctg ccgcaagtgt gctgaatgaa gcaaccgttg ccagtaatgc
     6481 ggcggcaatg atgcgttttt tcatagttct gttcctgttg cattgatgat aaggtttgcg
     6541 caatatcagt aatccgtaac gaaattattt atacccttca tacttcaggt tgcttatgtg
     6601 ttggctacgg attactcggc ccacccatgg gcctcgccct gacgggccgt cgcacgcgac
     6661 gttcaaatct gctcccggca gatttgtcgc tcacctcagt cacataatta tctatgctcc
     6721 tggtgactca ctcccttgcc gcctttaagc aactcgaatt attttgggta ataacctcgg
     6781 ttgattatct gaaaatagcc ttatttggtg tgaccgtctt atatcttgtt atagtcacct
     6841 ctttatgttg ttgtcaatgt aaaataatgc gctgccag
//
LOCUS       DAJVBX010000220         6771 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.220, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000220 DAJVBX010000000
VERSION     DAJVBX010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 6771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6771
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.220"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..864
                     /gene="prpB"
                     /locus_tag="OPV72_003966"
     CDS             <1..864
                     /gene="prpB"
                     /locus_tag="OPV72_003966"
                     /EC_number="4.1.3.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylisocitrate lyase"
                     /protein_id="HCR9916136.1"
                     /translation="AFRAALAKENPLQIVGAINANHALLAQRAGYQAIYLSGGGVAAG
                     SLGLPDLGISTLDDVLTDIRRITDVCPLPLLVDADIGFGSSAFNVARTVKSIAKAGAA
                     ALHIEDQVGAKRCGHRPNKAIVSKEEMVDRIRAAVDARTDPNFVIMARTDALAVEGLE
                     AALDRAQAYVDAGADMLFPEAITELSMYRQFADVAQVPILANITEFGATPLFTTDELR
                     SAHVAMALYPLSAFRAMNRAAEKVYTVLRQEGTQKNVIDIMQTRNELYESINYYQFEE
                     KLDALYRNKKS"
     gene            987..2156
                     /gene="prpC"
                     /locus_tag="OPV72_003967"
     CDS             987..2156
                     /gene="prpC"
                     /locus_tag="OPV72_003967"
                     /EC_number="2.3.3.16"
                     /EC_number="2.3.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-methylcitrate synthase"
                     /protein_id="HCR9916137.1"
                     /translation="MTDTTILQNNTHVIKPKKSVALSGVPAGNTALCTVGKSGNDLHY
                     RGYDILDLAEHCEFEEVAHLLIHGKLPTRDELNAYKSKLKALRGLPANVRTVLEALPA
                     ASHPMDVMRTGVSALGCTLPEKEGHTVSGARDIADKLLASLSSILLYWYHYSHNGERI
                     QPETDDDSIGGHFLHLLHGEKPTQSWEKAMHISLVLYAEHEFNASTFTSRVIAGTGSD
                     VYSAIIGAIGALRGPKHGGANEVSLEIQQRYETPDEAEADIRKRVENKEVVIGFGHPV
                     YTIADPRHQVIKRVAKQLSEEGGSLKMYHIADRLETVMWETKKMFPNLDWFSAVSYNM
                     MGVPTEMFTPLFVIARVTGWAAHIIEQRQDNKIIRPSANYTGPEDRVFVPIEKRC"
     gene            2194..3645
                     /locus_tag="OPV72_003968"
     CDS             2194..3645
                     /locus_tag="OPV72_003968"
                     /EC_number="4.2.1.3"
                     /EC_number="4.2.1.79"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-methylcitrate
                     dehydratase/aconitate hydratase"
                     /protein_id="HCR9916138.1"
                     /translation="MSAHISNVRPDFDREIVDIVDYVMNYEITSKVAYDTAHYCLLDT
                     LGCGLEALEYPACKKLLGPIVPGTVVPNGARVPGTQFQLDPVQAAFNISAMIRWLDFN
                     DTWLAAEWGHPSDNLGGILATADWLSRNAVAAGKAPLTMKQVLSGMIKAHEIQGCIAL
                     ENAFNRVGLDHVLLVKVASTAVVAEMLGLTRDEILNAVSLAWVDGQSLRTYRHAPNTG
                     TRKSWAAGDATSRAVRLALMAKTGEMGYPSALTAKTWGFYDVSFKGETFRFQRPYGSY
                     VMENVLFKISFPAEFHSQTAVEAAMTLYEQMQAAGKTAADIEKVTIRTHEACLRIIDK
                     KGPLNNPADRDHCIQYMVAVPLLFGRLTAADYEDEVAQDKRIDALREKIVCYEDPAFT
                     ADYHDPEKRAIGNAITVEFTDGSRFGEVVVEYPIGHARRRADGIPKLIEKFKINLARQ
                     FPTRQQQRILDVSLDRARLEQMPVNEYLDLYII"
     gene            3686..5572
                     /gene="prpE"
                     /locus_tag="OPV72_003969"
     CDS             3686..5572
                     /gene="prpE"
                     /locus_tag="OPV72_003969"
                     /EC_number="6.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propionate--CoA ligase"
                     /protein_id="HCR9916139.1"
                     /translation="MSFSEFYQRSINEPEAFWAEQARRIDWRQPFTQTLDHSRPPFAR
                     WFCGGTTNLCHNAVDRWRDKQPEALALIAVSSETDEERTFTFSQLHDEVNAVAAMLLS
                     LGVQRGDRVLVYMPMIAEAQITLLACARIGAIHSVVFGGFASHSVAARIDDARPALIV
                     SADAGARGGKILPYKKLLDDAIAQAQHQPKHVLLVDRGLAKMSWVDGRDLDFSTLRQQ
                     YLGASVPVAWLESNETSCILYTSGTTGKPKGVQRDVGGYAVALATSMDTIFGGKAGGV
                     FFCASDIGWVVGHSYIVYAPLLAGMATIVYEGLPTYPDCGVWWKIVEKYQVNRMFSAP
                     TAIRVLKKFPTAQIRNHDLSSLEALYLAGEPLDEPTASWVTETLGVPVIDNYWQTESG
                     WPIMALARALDDRPSRLGSPGVPMYGYNVQLLNEVTGEPCGINEKGMLVIEGPLPPGC
                     IQTIWGDDARFVKTYWSLFNRQVYATFDWGIRDAEGYYFILGRTDDVINIAGHRLGTR
                     EIEESISGYPNVAEVAVVGIKDALKGQVAVAFVIPKQSDTLADREAARDEEKAIMALV
                     DNQIGHFGRPAHVWFVSQLPKTRSGKMLRRTIQAICEGRDPGDLTTIDDPASLQQIRQ
                     AIEE"
     gene            complement(5676..6650)
                     /gene="hemB"
                     /locus_tag="OPV72_003970"
     CDS             complement(5676..6650)
                     /gene="hemB"
                     /locus_tag="OPV72_003970"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HCR9916140.1"
                     /translation="MTDLIHRPRRLRKSAALRAMFEETTLSLNDLVLPIFVEEELDDY
                     KAIDAMPGVMRIPEKQLAREIERIANAGIRSVMTFGISHHTDDTGSDTWKEDGLVARM
                     SRICKQTVPEMIVMSDTCFCEYTSHGHCGVLCEHGVDNDATLANLGKQAVIAAAAGAD
                     FIAPSAAMDGQVQAIRQALDAAGFTDTAIMSYSTKFASSFYGPFREAAGTALKGDRKT
                     YQMNPMNRREAIRESLLDEAQGADCLMVKPAGAYLDVLREIRERTELPLGAYQVSGEY
                     AMIKFAAMAGAIDEEKVVLESLGSIKRAGADLIFSYFALDLAEKNILR"
BASE COUNT         1478 a         1847 c         2010 g         1436 t
ORIGIN      
        1 gcatttcgcg ccgcgctcgc taaagagaat ccattacaaa ttgtcggcgc tattaatgcc
       61 aaccatgctc tgttggccca acgggccggg tatcaggcta tctatctttc tggcggcggc
      121 gtagcggcgg gctcgctcgg actgccggat ctggggattt cgacgctgga tgatgtgtta
      181 accgatatcc ggcgcatcac ggatgtttgc ccgctgccgc tgttggtgga tgcggatatt
      241 ggctttggct cctccgcctt taatgtcgcg cggacggtaa agtccatagc caaagcgggc
      301 gccgccgcgc tgcatattga agaccaggtt ggcgctaagc gctgtggaca ccgtccaaac
      361 aaagcgatcg tctcgaaaga ggagatggta gacagaattc gggcggcagt ggatgcgcgc
      421 accgatccga actttgtgat catggcgcgt accgatgcgc tggcggtgga agggctggag
      481 gcggctctcg atcgcgcgca ggcttacgtg gatgcggggg ctgacatgct gttcccggag
      541 gcgatcaccg aactgtcgat gtaccgccag ttcgccgacg tggcgcaggt gccgatcctc
      601 gccaacatca ctgagtttgg cgcgacgccg ctgtttacga ccgacgagtt gcgcagcgca
      661 cacgtggcga tggcgctcta tccgctgtcg gcgtttcgcg ccatgaaccg cgccgcagaa
      721 aaagtctata ccgtgctgcg ccaggaaggg acgcaaaaga acgtgatcga catcatgcag
      781 acccgcaacg agctgtacga aagcatcaat tactaccagt tcgaagagaa gctggacgcg
      841 ctgtacagga ataaaaaatc gtagcctgtg ggcctgataa ggcgaagccg ccatcaggca
      901 atgccggatg gcactacgtt tatcccgcct acggtacggc ctacacgcct caatacccta
      961 cacattacaa taatgacgag gacaatatga cagacacgac gatcctgcaa aacaacacgc
     1021 atgtcattaa gcctaaaaaa tcggtcgcgc tttccggcgt acctgccgga aataccgctc
     1081 tgtgtaccgt gggaaaaagc ggtaacgatc tgcactatcg cggttacgac attctcgatc
     1141 tggcggagca ctgcgaattt gaagaagtcg cgcatttact gatccacgga aaattaccga
     1201 cccgcgacga gctgaacgcg tataaaagca agttaaaagc gctgcgcgga ttacccgcca
     1261 atgtccgtac cgttctggaa gcgttaccgg cggcctcgca cccgatggac gtgatgcgta
     1321 ccggcgtttc cgcgctgggc tgcaccctgc cggaaaaaga gggacatacc gtctccggcg
     1381 cgcgcgatat tgccgataag ctgttggctt cgctcagctc tatccttctt tactggtatc
     1441 actacagcca caacggcgaa cgtattcagc cggaaaccga cgatgattcc atcggcggcc
     1501 atttcctgca tctgctgcac ggtgaaaagc caacccaaag ctgggaaaag gcgatgcata
     1561 tttcgctggt gctgtacgcc gagcatgagt tcaacgcctc gacgtttacc agccgggtaa
     1621 ttgccgggac cggctcggat gtctactccg cgattatcgg cgcgattggc gcgctgcgcg
     1681 gcccgaaaca cggcggagcg aatgaggtgt cgctggaaat tcaacagcgt tatgaaacac
     1741 cggacgaggc agaggcggat atccgtaaac gcgtggaaaa caaagaggtg gtgattggct
     1801 ttggacatcc ggtttacacc atcgccgacc cgcgccacca ggtgatcaaa cgggtggcga
     1861 aacagctttc agaagaaggc ggctcgctga agatgtacca catcgccgac cgtctggaaa
     1921 cggtgatgtg ggagaccaaa aagatgttcc cgaatctcga ctggttttcg gcggtctcct
     1981 acaacatgat gggcgtccct accgaaatgt tcaccccgct gtttgtcatc gcccgcgtta
     2041 ccggctgggc ggcgcacatt attgaacagc gtcaggacaa caaaattatt cgtccttccg
     2101 ccaattatac cggcccggaa gatcgcgtat ttgtgccgat cgaaaagcgt tgctaattaa
     2161 aacctctaaa tataaaaaca ggagttgtac cctatgtccg cacatatttc gaacgttcgc
     2221 ccagactttg accgtgaaat cgttgatatc gttgattacg ttatgaatta cgagatcacc
     2281 tcaaaggtgg cgtacgacac tgcgcattac tgcctgctcg acacgctcgg ctgtggtctg
     2341 gaagcgctgg aatacccggc ctgtaaaaaa ttgcttgggc caatcgtgcc aggcacggtg
     2401 gtgcccaacg gcgcacgcgt gccgggcacc cagttccagc tcgatccggt acaggcagcc
     2461 tttaacatta gcgcgatgat ccgctggctc gattttaacg atacctggct tgccgccgag
     2521 tggggccatc cttctgataa cctcggcggt attctggcga cggctgactg gctgtcacgc
     2581 aacgccgtcg ccgccggcaa agcgccgctg accatgaaac aggtattgag cgggatgatc
     2641 aaagcccatg aaattcaggg ctgcatcgcg ctggaaaacg ccttcaaccg tgtcgggctt
     2701 gaccatgtgc tgctggtcaa agtggcctcg accgcggtgg tcgctgaaat gctggggctg
     2761 acgcgcgatg agatcctcaa cgcggtatcg ctggcgtggg tggatgggca gtcgttgcgc
     2821 acttatcgtc atgcgccgaa taccggtacg cgcaaatcct gggcggcggg cgatgcgact
     2881 tcgcgcgcgg tacgtctggc gctgatggcg aaaaccggcg agatgggcta tccctcggcg
     2941 ctcaccgcca aaacctgggg cttctacgac gtttcattca aaggtgaaac gttccgtttc
     3001 cagcgccctt acggctccta cgtgatggaa aacgtgctat ttaaaatttc tttcccggca
     3061 gaattccact cgcaaaccgc cgtcgaagcg gcgatgacac tgtatgagca gatgcaggcc
     3121 gcgggcaaaa cggcagcgga tatcgagaaa gtgactatcc gcacccacga agcctgtctt
     3181 cgcattatcg ataaaaaagg cccgctcaat aacccggcgg accgcgatca ctgtatccag
     3241 tatatggtcg ccgtgccgtt gctgttcgga cggttaaccg cggcggatta tgaagacgag
     3301 gtggcgcagg acaagcgtat tgacgccctg cgcgagaaaa tcgtgtgcta tgaggacccg
     3361 gcttttaccg ccgactatca cgacccggaa aaacgtgcta tcggcaatgc gatcaccgtg
     3421 gagtttactg atggctcacg ctttggcgag gttgtcgtgg agtatccgat tggtcatgcg
     3481 cgtcgccgcg ccgacggtat tccgaagctt atcgaaaaat ttaaaattaa cctggcgcgt
     3541 cagttcccga ctcgccagca gcaacgcatt ctggatgtct ccctggacag agcccgcctg
     3601 gagcagatgc cggttaacga atacctcgat ttatatatca tctgagccag ccagcagtaa
     3661 ggcgtaagtt caacaggaga gcgtgatgtc ttttagcgaa ttttatcagc gttccattaa
     3721 cgaaccggag gcgttctggg ccgagcaggc ccggcgtatc gactggcgac agccgtttac
     3781 gcagacgctg gatcatagcc gtccaccgtt tgcccgctgg ttttgcggcg gcaccactaa
     3841 cttatgtcat aacgccgtcg accgctggcg ggataaacag ccggaggcgc tggcgctgat
     3901 tgccgtctca tcagagaccg atgaagagcg cacatttacc ttcagccagt tgcatgatga
     3961 agtcaacgct gtggccgcta tgctgctgtc gctgggcgtg cagcgtggcg atcgcgtatt
     4021 ggtctatatg ccgatgattg ccgaagcgca gataaccctg ctggcctgtg cgcgcattgg
     4081 cgcgatccat tcggtggtct ttggcggttt tgcctcgcac agcgtggcgg cgcgcattga
     4141 cgatgccaga ccggcgctga ttgtgtcggc ggatgccgga gcgcgtggcg gtaaaattct
     4201 gccgtataaa aagctgcttg atgacgctat tgcgcaggcg cagcatcagc cgaaacacgt
     4261 tctgctggtg gacagagggc tggcgaaaat gtcgtgggtg gatgggcgcg atctggattt
     4321 ttccacgttg cgccagcagt atctcggcgc gagcgtgccg gtggcgtggc tggaatccaa
     4381 tgaaacctcg tgcattcttt acacctccgg cactaccggc aaaccgaaag gcgtccagcg
     4441 cgacgtcggc ggttatgcgg tggcgctggc aacctcgatg gacaccattt ttggcggcaa
     4501 ggcgggcggc gtattctttt gcgcatcgga tatcggctgg gtcgtcggcc actcctatat
     4561 cgtttacgcg ccgctgctgg caggcatggc gactattgtt tacgaaggac tgccgacgta
     4621 cccggactgc ggggtctggt ggaaaattgt cgagaaatac caggttaacc ggatgttttc
     4681 cgccccgacc gcgattcgcg tgctgaaaaa attcccgacg gcgcaaatcc gcaatcacga
     4741 tctctcctcg ctggaggcgc tttatctggc cggtgagccg ctggacgagc cgacggccag
     4801 ttgggtgacg gagacgctgg gcgtaccggt catcgacaat tattggcaga cggagtccgg
     4861 ctggccgatc atggcgctgg cccgcgcgct ggacgacagg ccgtcgcgtc tgggaagtcc
     4921 cggggtgccg atgtacggtt ataacgtcca gctactcaat gaagtcaccg gcgaaccctg
     4981 cggcataaat gaaaaaggca tgctggtgat cgaagggccg ctgccgccgg gttgtattca
     5041 gactatttgg ggcgacgatg cgcgttttgt gaagacttac tggtcgctgt ttaaccgtca
     5101 ggtttatgcc actttcgact ggggaatccg cgacgccgag gggtattact ttattctggg
     5161 ccgtaccgat gatgtgatta atattgcggg tcatcggctg gggacgcgag aaatagaaga
     5221 aagtatctcc ggttacccga acgtagcgga agtggcggtg gtggggataa aagacgctct
     5281 gaaagggcag gtggcggtgg cgtttgtcat tccgaagcag agcgatacgc tggcggatcg
     5341 cgaggcggcg cgcgacgagg aaaaagcgat tatggcgctg gtggataacc agatcggtca
     5401 ctttggtcgt ccggcgcatg tctggtttgt ttcgcagctc cccaaaacgc gttccggaaa
     5461 gatgcttcgc cgcacgatcc aggcgatctg cgaaggccgt gatccgggcg atctgacaac
     5521 cattgacgat cccgcgtcgt tgcagcaaat tcgccaggcg atcgaggaat agccgtaagc
     5581 cggataagcc gcgtccggca acgggttaga ctcagcgact gaatagtggg gtgtaaagtc
     5641 gggaaagggc ggcagcgcgc cgccctgtaa cagaattaac gcagaatatt tttctcagcc
     5701 agatccagtg cgaagtagct gaaaatcaaa tcggcgccgg cgcgtttaat cgagcccaga
     5761 ctttccagca cgaccttttc ttcatcgatg gcgccagcca tagcagcaaa tttaatcatg
     5821 gcgtattcac cgctcacctg gtaagcgcca agcggcaact ctgtgcgttc gcgaatttca
     5881 cgcagcacgt ccagatacgc gccggccggt ttcaccatta agcaatccgc gccctgggct
     5941 tcgtcgagca gtgattcgcg aatcgcttca cggcggttca tcggattcat ttgatacgtc
     6001 ttgcggtcgc cttttaacgc ggtacccgct gcttcacgga aggggccgta gaaagaagag
     6061 gcgaacttgg tggagtagga cattattgcc gtatcggtaa aaccggcggc atccagcgct
     6121 tggcggatag cctggacttg tccatccatt gccgcggagg gcgcaataaa atctgctcca
     6181 gccgccgccg cgataacggc ctgcttgccg aggttggcca gcgtcgcatc gttatccaca
     6241 ccgtgttcgc acaacacgcc gcagtggccg tgcgaggtgt attcgcagaa gcaggtgtcg
     6301 gacatgacga tcatctccgg cacggtttgc ttacagatgc gggacattct tgccaccagg
     6361 ccgtcttctt tccaggtatc gctgccggtg tcatcagtat ggtgagaaat gccgaaggtc
     6421 ataacggaac gaatgccagc atttgcgata cgttcaatct ctcgcgccag ctgcttttcc
     6481 gggatacgca ttacgccggg catggcatca atagctttgt aatcgtcgag ttcttcttca
     6541 acaaagatcg gcaacaccag gtcgttcagg ctaagtgttg tctcttcaaa catagcgcgc
     6601 agcgcagcgg atttgcgcag gcggcgaggg cgatggataa ggtctgtcat ggtctgcctg
     6661 atgtttgtgg aatcgaaggc ccagtatacc tgaatctgca ggcagatgtt ttacgaaaac
     6721 ggtccttaac gtagcaggcg cagccccggc ggcggcagaa catggcgctt c
//
LOCUS       DAJVBX010000221         6694 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.221, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000221 DAJVBX010000000
VERSION     DAJVBX010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 6694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6694
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.221"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            132..1268
                     /locus_tag="OPV72_003971"
     CDS             132..1268
                     /locus_tag="OPV72_003971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpC"
                     /protein_id="HCR9916141.1"
                     /translation="MKVKVLSLLVPALLVAGAANAAEIYNKDGNKLDLFGKVDGLHYF
                     SDDKGSDGDQTYMRIGFKGETQVNDQLTGYGQWEYQIQGNQTEGSNDSWTRVAFAGLK
                     FADAGSFDYGRNYGVTYDVTSWTDVLPEFGGDTYGADNFMQQRGNGYATYRNTDFFGL
                     VDGLDFALQYQGKNGSVSGENTNGRSLLNQNGDGYGGSLTYAIGEGFSVGGAITTSKR
                     TADQNNTANARLYGNGDRATVYTGGLKYDANNIYLAAQYSQTYNATRFGTSNGSNPST
                     SYGFANKAQNFEVVAQYQFDFGLRPSVAYLQSKGKDISNGYGASYGDQDIVKYVDVGA
                     TYYFNKNMSTYVDYKINLLDKNDFTRDAGINTDDIVALGLVYQF"
     gene            1383..2435
                     /gene="apbE"
                     /locus_tag="OPV72_003972"
     CDS             1383..2435
                     /gene="apbE"
                     /locus_tag="OPV72_003972"
                     /EC_number="2.7.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase ApbE"
                     /protein_id="HCR9916142.1"
                     /translation="MKMTFCRAVCLAAAFLLMGCDEAPETTTASPAAQVLEGKTMGTL
                     WRVSVVGIDAKRAAELQTKIQTQLDADDWLLSTYKNDSALMRFNHSRSLAPWPVSEAM
                     ADIVTSALRIGAKTDGAMDITVGPLVNLWGFGPDRQPLHIPTPAQIDAAKAKTGLQHL
                     QVIDRAGHQFLQKDLPDLYVDLSTVGEGYAADHLARLMEQEGIARYLVSVGGALSSRG
                     MNAQGLPWRVAIQKPTDRENAVQAIVDINGHGISTSGSYRNYYELDGKRVSHVIDPQT
                     GRPIEHNLVSVTVIAPTALEADGWDTGLMVLGTQKAQEVVRREGLAVFMIMKEGEGFK
                     TWMSPQFKTFLVSDKN"
     gene            2516..3577
                     /gene="ada"
                     /locus_tag="OPV72_003973"
     CDS             2516..3577
                     /gene="ada"
                     /locus_tag="OPV72_003973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA-binding transcriptional
                     regulator/O6-methylguanine-DNA methyltransferase Ada"
                     /protein_id="HCR9916143.1"
                     /translation="MMKKALLTDDECWLRVQARDASADGRFVFAVRTTGVFCRPSCRS
                     KRALRKNVRFFANAQQALDAGFRPCKRCQPDNARAQQRRLDKIACACRLLEQETPVTL
                     ASLAQAVAMSPFHLHRLFKASTGMTPKGWQQAWRARRLREALAKGEPITAAIYRAGFP
                     DSSSYYRHADQTLGMTAKQFRKGGDNVSVRYALTDWVYGRCLVAESGRGICAILPGDS
                     DDALLAELHTLFPAARHEPADAPFQQRVRQVVAAINTRDVLLSLPLDIQGTAFQQQVW
                     QALCAIPCGETVSYQQLAATIGKPTAVRAVASACGANKLAMVIPCHRVVRRDGALSGY
                     RWGVRRKAQLLKREAQKEE"
     gene            3580..4230
                     /gene="alkB"
                     /locus_tag="OPV72_003974"
     CDS             3580..4230
                     /gene="alkB"
                     /locus_tag="OPV72_003974"
                     /EC_number="1.14.11.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA oxidative demethylase AlkB"
                     /protein_id="HCR9916144.1"
                     /translation="MLDLFADEAPWQEPLAPGAVVLRRFAFRAAQSLLDDIGFVASQS
                     PFRQMVTPGGYTMSVAMTNCGALGWTTDGHGYCYAVRDPLTDKPWPALPLSFASVCRQ
                     AAIAAGYASFQPDACLINRYAPGAKLSLHQDKDEPDLRAPIVSVSLGVPAVFQFGGLR
                     RSDPLQRILLEHGDIVVWGGESRLFYHGIQPLKAGFHPMTGEFRYNLTFRQAAEKE"
     gene            4306..5949
                     /locus_tag="OPV72_003975"
     CDS             4306..5949
                     /locus_tag="OPV72_003975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug ABC transporter permease/ATP-binding
                     protein"
                     /protein_id="HCR9916145.1"
                     /translation="MELLILVWRQYRWPFISVMALSLASAALGIGLIAFINQRLIETV
                     DTTVMVLPEFLGLLLLLMVVTLGSQLALTALGHHFVYRLRSEFIKRILDTHVERIEQL
                     GSASLLAGLTSDIRNITIAFVRLPELVQGIVLTVGSAAYLAMLSTKMLLVTAIWMAVT
                     IWGGFVLVARVYQHMATLRETEDKLYNDYQTVLEGRKELTLNRERAEQIFQQCYTPDA
                     KEYRHHIIRADTFHLSAVNWSNIMMLGAIGLVFWMANSLGWADTNVAATYSLTLLFLR
                     TPLLSAVGALPTLLTAQVAFNKLNKFALAPYKPDFPQPKAFPDWKTLELRNVVFHYQD
                     NAFSVGPINLTIHRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGTILLDGQPVAAGQP
                     EDYRKLFSAVFTDVWLFDRLLGPQGKPANPALVEKWLEHLKMTHKLELNDGCILNLKL
                     SKGQKKRIALLLALAEERDIILLDEWAADQDPHFRREFYQVLLPLMQEMGKTIFAISH
                     DDHYFIHADRLLEMRNGQLTELTGDERDAASRDAVARTA"
     gene            complement(6158..6652)
                     /gene="eco"
                     /locus_tag="OPV72_003976"
     CDS             complement(6158..6652)
                     /gene="eco"
                     /locus_tag="OPV72_003976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease inhibitor ecotin"
                     /protein_id="HCR9916146.1"
                     /translation="MKMFVPAVVFAALASASAWANNGDTAQPLEKIAPYPQAEKGMKR
                     QVITLTPQQDESTLKVELLIGQTLNVDCNQHRLGGTLETKTLEGWGYDYYVFDNVTSP
                     VSTMMACPEGKKEQKFVTAWLGEDGMLRYNSKLPIVVYTPANVDVKYRIWKADANVQN
                     AIAR"
BASE COUNT         1425 a         1743 c         1977 g         1549 t
ORIGIN      
        1 tttagtatca tattcgtgtt ggattattct gtatttttgc ggagaatgga cttgccgact
       61 ggttaatgag ggttaaccag taagcagtgg cataaaaaag caataaaggc atataacaga
      121 gggttaataa catgaaagtt aaagtactgt ccctcctggt accagctctg ctggtggcgg
      181 gcgcagcgaa tgcggctgaa atttataata aagacggcaa caaattagac ctgtttggta
      241 aagttgatgg cctgcactac ttctctgacg acaaaggcag cgacggcgac cagacctaca
      301 tgcgtatcgg cttcaaaggc gaaacgcagg ttaacgatca gctgaccggt tatggccagt
      361 gggaatatca gattcagggc aaccagactg aaggcagcaa cgactcctgg acgcgtgtgg
      421 cgtttgcggg tctgaaattc gctgacgcag gttccttcga ttatggtcgt aactacggcg
      481 taacctatga cgtgacctcc tggaccgacg ttctgccgga gttcggcggc gacacctacg
      541 gcgctgacaa ctttatgcag cagcgtggta acggctatgc tacctaccgt aacaccgact
      601 tcttcggtct ggtggatggt ctggacttcg cgttgcagta tcagggcaaa aacggcagcg
      661 tgagcggtga aaacaccaac ggtcgcagcc tgctgaacca gaacggcgac ggttacggcg
      721 gatcgctgac ttatgcaatc ggcgaaggct tctctgtcgg tggcgctatc accacgtcta
      781 aacgtactgc cgatcagaac aacaccgcta acgctcgcct gtatggtaac ggcgatcgcg
      841 ccacggttta caccggcggc ctgaaatacg atgcgaacaa catctatctg gcagcgcagt
      901 attctcagac ctataacgca acccgttttg gtacctctaa cggcagcaac ccgtccacct
      961 cttacggttt tgccaacaaa gcgcagaact ttgaagtggt tgctcagtac cagttcgact
     1021 ttggtctgcg tccgtctgtg gcttacctgc agtctaaagg taaggacatc agcaacggct
     1081 acggcgccag ctatggcgac caggacatcg taaaatacgt tgatgtcggc gcgacttact
     1141 acttcaacaa aaacatgtcc acctatgttg attacaaaat caacctgctg gataaaaacg
     1201 actttacccg cgatgcgggc atcaacaccg acgacatcgt agcgctgggt ctggtttacc
     1261 agttctaatc agcaaaagat gttgctaaag ggcctgcggg cccttttttc atgccttatt
     1321 ccggcgtaca aatacgacgt tttgatatac gcttgcgtcc attcgaatga ggataaacag
     1381 cgatgaaaat gactttttgc cgggccgtgt gtctggcagc ggctttttta cttatgggct
     1441 gcgatgaggc tcccgaaacg acaacagcgt cacctgccgc tcaggtgctg gaaggtaaaa
     1501 cgatgggaac cctctggcgg gtgagcgtgg ttggtatcga tgcgaaacgt gccgcagagt
     1561 tacagactaa aatccagact cagcttgatg ctgatgattg gttgctttct acctataaaa
     1621 atgactccgc gctgatgcgt tttaaccatt cacgcagtct tgcgccctgg ccggtcagcg
     1681 aagccatggc ggatatcgtg acctcggcgc tgcgtattgg cgcgaagacg gacggcgcga
     1741 tggatatcac cgtgggcccg ctggtcaatc tgtgggggtt tggaccggat cggcagccgc
     1801 tgcatatccc aacaccagca caaatcgatg cggcaaaagc gaaaacaggc ctgcaacatt
     1861 tgcaggttat cgacagggct ggacatcagt ttttgcaaaa agatctgccg gatctttatg
     1921 ttgatctctc cacggtcggg gagggctatg cggcggatca tctggcgcgt ctgatggagc
     1981 aggagggcat tgcgcgttat ctggtctcgg tgggcggcgc attaagcagt cgcgggatga
     2041 atgcgcaggg gctgccgtgg cgcgtcgcga ttcagaagcc gaccgaccgg gaaaacgcgg
     2101 tgcaggcgat tgtggatatc aacgggcatg gcatcagcac ctccggcagc taccgtaact
     2161 attacgagct ggatggcaag cgcgtatcgc acgttatcga tccgcaaacg gggcgcccca
     2221 ttgaacacaa tctggtatcg gttacggtca tcgcgccaac ggcgctggaa gcggacggct
     2281 gggacaccgg cctgatggtg ctcggtacgc aaaaggcgca agaggtcgtg cggcgggaag
     2341 ggctggcggt ctttatgatc atgaaagaag gtgaaggctt taaaacctgg atgtcgccgc
     2401 agttcaaaac attcctggtg agcgataaga attaaaacgc aagattacgg gtttttgtgg
     2461 gcggatttac ggacacactg catgtaagca agcactatgc ttaatgaagg agtctatgat
     2521 gaaaaaagcg ttacttaccg atgatgaatg ctggctgcgg gtgcaggcgc gcgatgccag
     2581 cgcggatggg cgtttcgttt ttgcagtgcg aaccactggc gttttttgcc gcccttcttg
     2641 tcgctcgaag cgggcgttac gtaaaaatgt tcgctttttt gccaacgcgc agcaggcgct
     2701 ggacgccggt tttcgcccct gcaagcgctg tcagccggat aatgcgcgcg cgcagcaacg
     2761 gcggttggat aagattgcct gcgcctgccg tttacttgag caggagacgc cggtaacgct
     2821 ggcgtctctg gcgcaggcgg tggcaatgag tccgtttcat ctgcaccgtt tgtttaaagc
     2881 gagcaccgga atgacgccga aagggtggca gcaggcgtgg cgcgcccggc ggctgcgtga
     2941 ggcgttggcg aaaggagagc cgatcacggc ggctatttac cgcgccggct tcccggatag
     3001 cagtagctac tatcgtcatg ccgaccagac gctgggcatg acggcaaaac agtttcgcaa
     3061 aggcggcgat aatgtctccg ttcgctatgc gctgacggac tgggtttacg gacggtgcct
     3121 ggtggcggag agcgggcggg ggatttgcgc gattctcccc ggtgatagcg acgatgcgct
     3181 actggccgaa ttacacaccc ttttcccggc ggcccgccac gaacctgctg acgcgccttt
     3241 tcagcaacgg gtgcggcagg ttgtcgcggc tatcaacaca cgcgatgtgc tgctctcgtt
     3301 gccgctggat atccagggaa ccgcgtttca acagcaggtc tggcaggcgt tatgcgcgat
     3361 tccctgcggc gaaaccgtaa gctatcaaca gcttgccgcg actatcggca aacccacggc
     3421 agtacgcgcg gtcgccagcg cgtgcggcgc gaataaactg gcgatggtga tcccgtgtca
     3481 tcgggtcgtg cgtcgcgatg gcgcgctctc cggttatcgt tggggcgtgc gtcgaaaagc
     3541 gcagctatta aagcgagaag cgcaaaaaga ggagtagcaa tgctggatct gtttgctgat
     3601 gaagcgccct ggcaagagcc cctggcgcct ggcgcggtgg tgttgcgccg ctttgcgttt
     3661 cgcgcggcgc agtcgctatt agacgatatc ggatttgtcg ccagtcagtc accgtttcgt
     3721 cagatggtga cgccgggcgg ctacactatg tcggtggcga tgaccaactg cggcgcgtta
     3781 gggtggacca ccgatggtca cggttattgt tatgccgtgc gcgatccgtt gaccgataaa
     3841 ccctggcctg cgctgccgtt atcgtttgcc agcgtatgtc gtcaggcggc aatcgcggca
     3901 gggtatgcta gcttccaacc ggacgcctgc ctgatcaatc gctacgcgcc tggcgcaaaa
     3961 ctgtcgctgc atcaggataa agacgagccg gatctgcgcg cgcctatcgt ctcagtttcg
     4021 ttgggggtgc cggcggtttt tcagtttggc ggcctgcgtc gcagcgatcc gctccagcgg
     4081 atcttactgg agcatggcga tatcgtggtc tggggcggcg agtcccgcct gttttatcac
     4141 ggtatccagc cgcttaaagc gggctttcat cccatgaccg gtgaatttcg ttacaatctc
     4201 accttccgtc aggcggctga aaaagaataa aaataagaat tattattgct gtgcaggtag
     4261 agttagttaa actgcgggct gttattatcg gtccgggttg tatgcatgga acttcttatt
     4321 cttgtctggc ggcagtaccg ctggccattt attagcgtga tggcgctgag cctcgccagc
     4381 gcggcgctgg ggattggcct gatcgcgttt atcaatcagc gcctgattga aacggtggac
     4441 accaccgtca tggtgctgcc ggaatttctc ggtctgctcc tgttgctaat ggttgtcaca
     4501 ttaggttccc aactggcgct caccgctctg ggacaccatt tcgtttaccg cctgcgcagc
     4561 gaatttatca agcgcattct ggatacgcac gttgaacgca ttgagcaact gggcagcgcc
     4621 tctttactgg ccggtctgac cagcgatatt cgcaatatta ctatcgcctt tgtgcgtctg
     4681 cctgagctgg tgcagggcat tgtcctcacc gtcggctcgg cggcgtatct ggcgatgcta
     4741 tcgacaaaaa tgctgctggt tacggctatc tggatggcgg tcactatctg gggcggattc
     4801 gtgctggtgg cgcgggttta ccagcatatg gcgaccctgc gcgagaccga agataagctg
     4861 tacaacgact atcagacggt gctggaggga cgcaaagagc tgacgctaaa ccgcgagcgt
     4921 gcggagcaga tttttcagca atgctatacc ccggacgcca aagagtaccg tcatcacatt
     4981 atccgtgccg atacttttca cctgagcgcc gtcaactggt cgaatatcat gatgctgggg
     5041 gcgataggcc tggtcttctg gatggcgaat agtctcggct gggcggatac caacgtcgcg
     5101 gcgacctatt cactgacgtt gctgttcctg cgcacgccgc tgctgtctgc ggtgggggcg
     5161 ttgccaacgc tactgaccgc ccaggtggcg tttaataaac tgaataaatt cgcgctcgcc
     5221 ccgtataagc ctgattttcc acagccgaaa gcctttcccg actggaagac gctggagctg
     5281 cgcaacgtgg tttttcacta tcaggataac gcgttttccg tggggcccat caacctgacg
     5341 attcaccgcg gcgaactgct gtttttaatt ggcggcaacg gtagcgggaa atcgacgctg
     5401 gccatgttat tgaccggttt ataccagccg caatcgggaa cgattttact tgacggtcaa
     5461 cctgttgccg ccgggcagcc ggaagattat cgcaaactgt tttctgcggt gttcaccgat
     5521 gtgtggttat tcgaccgcct gctggggccg caggggaaac ccgccaatcc cgcgctggtc
     5581 gaaaagtggc ttgagcacct gaaaatgacg cacaagctgg agctaaacga tgggtgcatc
     5641 ttgaatctta aactgtcgaa agggcaaaaa aagcgcattg cgctgctgct ggcgctggcg
     5701 gaagagcgcg atattatttt gctggatgag tgggccgccg atcaggaccc gcatttccgc
     5761 cgggaatttt atcaggtact gttgccgtta atgcaggaaa tgggcaaaac cattttcgcc
     5821 atcagccatg atgatcacta ttttattcac gccgatcgcc tgcttgaaat gcgtaacggg
     5881 cagttaaccg aactcaccgg cgacgaacgt gacgccgctt cgcgtgatgc ggttgcgcgt
     5941 actgcgtaat ggactatggc gccggataaa ctgcctgatg gcagccctac gtccgcacgc
     6001 gggtaggcct gataagatgc cacgcgtcgc caccaggcat cggggtattt tttgcggcgg
     6061 gcgagcgggt ttccagacgt gttttaaaaa gaaccccgga gcgctgcgtg agtcggcgtg
     6121 ttcagatgcc cggtaagtgt gaccgggcag cgtaacatta tcgcgcgatg gcattctgta
     6181 cgttagcgtc cgctttccag atgcggtatt tcacgtccac attcgccggg gtatacacca
     6241 cgatcggcag cttgctgttg tagcgcagca tcccgtcttc acccagccag gcggtgacga
     6301 atttttgctc tttcttacct tcagggcagg ccatcatggt tgataccgga gaggtgacgt
     6361 tatcaaagac ataatagtcg tagccccagc cttccagcgt ttttgtttcc agcgtgccgc
     6421 cgaggcgatg ctggttacaa tccacattca gcgtttgacc aatcaacagt tccactttga
     6481 gggtagattc atcctgctga ggggtaaggg ttatcacttg ccgcttcatt cctttctccg
     6541 cctgcggata gggggcgatt ttttccagcg gctgggcggt atcgccattg ttagcccagg
     6601 cagaggcgct ggcgagggcg gcgaagacga cggcagggac aaacatcttc atttgattgt
     6661 tcacagtatt tcctttctgc tgttttcggt atgc
//
LOCUS       DAJVBX010000222         6622 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.222, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000222 DAJVBX010000000
VERSION     DAJVBX010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 6622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6622
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.222"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..6412
                     /gene="siiE"
                     /locus_tag="OPV72_003977"
     CDS             <1..6412
                     /gene="siiE"
                     /locus_tag="OPV72_003977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="non-fimbrial adhesin SiiE"
                     /protein_id="HCR9916147.1"
                     /translation="VPTIALDAGQDTGANTADNITNISRPTFTIGNVDPDVIKVVVTI
                     DGHDYNATKVGAGWQFTPGNAIPDGSYNITVTVEDKAGNTATSKPLPVVIDTTAEIES
                     VTLVTDSGDSDVDNITKVDKPQFSIVTADDITHVRVKIDNAANWIELTKGGDGRWIFN
                     VGSALPDGQHTLLVDVTDIAGNVAQETLQFTIDTTLREPTIVLDPTHDTGDDTNDNLT
                     RINKPVFIIGNVDNDVSHIVVHLDGRDYTIENKGGNLTFTPDQPLSDGQHTISVTVTD
                     IAGNTKTSAELQIEIDTQVQIDSVTLTTDSGVNDHDNVTNATRPSFEIATPDDVTSVL
                     VSFDGVNWTPISKNAAGQWQFTAGSALSDGHYTLHVQATDRAGNTANSTLGFTVDTQI
                     DGLSVVMLDDAGKDSTDGITNITSPRFEISAREQLQSVTVILNGKSSTLTQGAGNKWL
                     FTPDTPLVDGTYKIEIVAEDIAGNKISKEVSFTIDTIVSDPSIDLLDADDTGESAVDN
                     ITSVTTPRFVIGNVPADIDTVVIRINGVSYPVTANGNNLWEFQVPVALNDGVYEAVVV
                     FRDIAGNTSETKLPFTIDTTTSVSVRMEPASDTGSSNSDNLTNKQNPKFEGTAEPNAK
                     LVITIVDDKSGREVLKHTITVGADGNWSVTPNILPDGMYTINVVATDVAGNTAQTQER
                     FTIDTVTIDPTIRLSDPSIDDQYEATSLRPEFKGLAEAFSTIMIQWDGKVVGSANANA
                     NGEWSWTPPSVLAPGSYVVSIVAKDKAGNESSQVDFPVVIPVIDVTPPTIKLSEESDS
                     GALGDFTTNNKTPTLIGSTLPNTIVSIYVDGVKVGEATADTAGRYTFQLSEMKDGHYV
                     VQVGIVNPRDNSELRSTAVDVTIDTEVAELVWNISGMHEGGYINTVTPEIGGTSEPNS
                     KITIFVNGVEKAIAYTTGAGHWGVVLPALGNDGNYELTFKVEDVAGNIREFGPQNVIL
                     DTVISPLTVVLREADDSGKVGDWITNKSHVTIDGTAEAGSTLTIRNPQGVVIATLVVG
                     NDGRWSAELDLREGSNAFVVVSEDKAGNGQQKDILIEHDTQIEISDISLSRDTNSGDK
                     YDLITNNKSPVLVAMTDPGATVQVYINGVLQGTVEASSSGNISYTMPANSADGEYQVQ
                     FVATDTAGNRVESAITTVTIDSQIAVFDIDEDSLPALSNNRALSVSGVGEAGSQVSIF
                     VDGKLVNVVMVEADGSWRAPILLQDDGTFNIHFSITDVAGNTQVSKNYSVDVDSSTDF
                     PTLNLEDASNSGSLDDLITNHNKPVLVGTAEAGATIHIYVDEKIVANVLVLEDGTWSY
                     QFDNALKDGEYSIRVVAEDPAGNTAESPRLLVTIDTSTFIDNPAMVAGSDNGIFSNDS
                     ITSQTRPTFSIFGEMNQSVQIFIDGVLVDTITVTDRNQVYRPESPLGDGSHSIYYVIT
                     DKAGNTATSKTLNFTIDTFNTTPVAIDSIGGQTLAEMTGSDGKIYITDTTRNLLFSGS
                     AEPNSKIEIIINGLNVGEVWVNEKGHWQMPVNPLYFTEGQLDITVKSTDRAGNVNQEK
                     YSIWVDTHIQVFTSELDDNKSSSKTDWWSNSSTITMRGMGEIGATVSLIVAGVTLATA
                     VVAANGQWELSTDQLPEGKYDITLSIEDNAGNRKEEVHEIFIDRTPPNAPVVTYSDIV
                     NDLIIMQGTAEAKSQLIITDSNGNTYTLTVPDNGKWSMAIPYPSEGKFTITSVDAIGN
                     RSDDVPLDIMKEVPVISLSPDSDSGTVGDNITRDKQPTFIIGNLESDVVVVQVDINGT
                     VYNAEKNADGVWFFTPGTPLADGSYTISVIASDAAGNQKNSLPITVTIDSTLTVPEIA
                     LAAGEDNGVSDSDNVTNHTQPKFTLQHIDADVTGVTVNVTHNGVTDTYQATQGADGWT
                     FTPPAAWNDGTYTLSVTVVDRAGNSQQSASLAVTVDSTVTVTADSQHDDASDDATPTA
                     VTPPESETVNAESDTHLRTVPSAAEESVVKETAYSITLLNANSGDEIDRSISQTPSFE
                     ISVPENIVNVSVMFEGEEFTLPITNQKAIFEVPLSLEDGEYTMDVKFIDKDDDFLIKE
                     KTFSVDHSSADIVNAMNARGKTEDDINDSPSTSSVGHNNNGAIDVFAVNEVTLPVDNQ
                     EEHA"
     gene            6452..>6622
                     /locus_tag="OPV72_003978"
     CDS             6452..>6622
                     /locus_tag="OPV72_003978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-1 secretion protein"
                     /protein_id="HCR9916148.1"
                     /translation="MDKKLEPYYLSAETALSIVSKKFNIKIDIKEDDINLRFKKYDRN
                     NTDDSIQMKNFFL"
BASE COUNT         1878 a         1366 c         1687 g         1691 t
ORIGIN      
        1 ggttccgact attgctttag acgcaggaca agataccgga gcgaatacag ccgataatat
       61 tactaatatt tcacgaccca cctttacgat tggtaatgtt gaccccgatg ttatcaaagt
      121 cgtggtgacg attgatggtc atgattataa cgcgactaag gttggggctg gttggcaatt
      181 tacaccaggc aatgccattc cggatggttc ttataatatt accgttacgg ttgaagataa
      241 ggccggaaat accgcgacat cgaaaccatt acctgttgtg atagatacga cggctgaaat
      301 tgaaagcgtc acgttggtta cagatagcgg tgatagcgat gtagataaca ttaccaaagt
      361 cgacaagccg cagtttagta ttgttaccgc tgatgatatt acccatgtgc gcgttaaaat
      421 cgataacgcc gctaattgga ttgaactcac aaaaggaggg gatggtcgct ggatatttaa
      481 tgtcggttcg gcattacctg atgggcaaca cactctcttg gttgatgtga ctgatatcgc
      541 cggcaacgtt gcgcaagaaa cgctgcagtt tacgattgat acgactctgc gagagccgac
      601 aattgtactc gatcccaccc atgatactgg tgatgatact aatgataatc ttaccaggat
      661 taacaaaccg gtgtttatta tcggtaatgt cgataatgat gtatcacaca ttgtggttca
      721 tcttgatggt cgggattaca ccattgaaaa caaagggggg aatttaacct ttacgccgga
      781 tcaaccgctg tctgacggtc agcatacgat ctctgttacc gtaacggata ttgctggtaa
      841 taccaaaaca tcggccgaac tgcagattga aatcgacacg caggttcaga ttgacagtgt
      901 tacgttaaca acagatagcg gcgtcaacga tcacgataat gtcaccaatg ctacccgtcc
      961 ctcttttgaa attgcaacgc ctgatgatgt gacatcggtg ctggtttctt tcgatggcgt
     1021 aaactggacg cccatcagta aaaatgcggc cgggcagtgg caatttactg caggtagcgc
     1081 attgtctgat ggtcattata ctctccatgt ccaggcgacg gatcgggcag ggaatacggc
     1141 aaattccacg ctgggcttta ccgtggatac gcagattgac ggcctgagcg tcgtgatgct
     1201 ggacgacgcc ggaaaggatt ctacggatgg tattacgaat attacctctc cacgttttga
     1261 aatttcagcc agagaacagt tgcagagcgt gacggtaatt ttaaacggga aatccagcac
     1321 cctgactcag ggggcaggta ataaatggct gtttacccct gatacaccgt tagtggatgg
     1381 aacttacaaa atagaaatag tggctgaaga tatcgcaggt aataaaatta gcaaagaggt
     1441 atcattcaca atagacacta ttgtttctga tcccagtatt gatttgctgg atgcggatga
     1501 tactggcgaa agcgctgttg ataatattac gagtgtcact acaccacgtt tcgttattgg
     1561 caatgtaccc gccgatattg atactgttgt aatcagaatt aacggcgttt cttatccggt
     1621 tacggcaaat ggcaataacc tctgggaatt tcaggttccc gttgcgttaa acgatggcgt
     1681 atatgaagcc gttgttgtct tcagagatat tgccggaaat acttctgaaa ctaagctgcc
     1741 ctttaccatt gataccacga caagcgtcag tgtcagaatg gagccagcgt ctgataccgg
     1801 cagctccaat agcgataacc ttacgaataa gcaaaatccc aaattcgaag gtactgcaga
     1861 gcccaatgcg aaactggtga ttaccattgt tgacgataag tcaggtcggg aggttttaaa
     1921 acacacgatt acggttggcg ccgatggcaa ctggagtgtg acgccgaata tactgccgga
     1981 tggcatgtat accatcaacg tcgtcgcaac agatgtcgcg ggaaatactg cgcaaacgca
     2041 ggaaagattc actatcgata cggttacgat cgatcccacc attcgccttt cggatccatc
     2101 tattgatgat cagtatgagg caaccagcct gcgtcctgag ttcaaagggc tcgccgaagc
     2161 gttctcgacg attatgattc agtgggatgg gaaagtggtc ggctcggcaa acgccaatgc
     2221 gaatggtgaa tggagttgga cgccgccatc agtattagcg ccaggctcct atgttgtgag
     2281 cattgttgcc aaagataaag cgggtaatga atcgtcgcag gtcgactttc ctgtagtaat
     2341 acctgttatt gatgtcacgc ctccaaccat aaagctcagc gaggagagcg atagtggtgc
     2401 cttaggagac tttacgacga ataataaaac gccgaccctg attgggagca cgttacctaa
     2461 tacaattgtg agtatttatg tggatggcgt gaaggtcggc gaggcgacag cggatacagc
     2521 gggccgatat actttccagt tatcggaaat gaaagatggc cattatgtcg tccaggtggg
     2581 tatcgtcaac cctcgcgata atagcgaact gcgttccacc gccgttgatg tcactatcga
     2641 taccgaggtt gctgaactgg tatggaatat atctggaatg catgagggcg gatatatcaa
     2701 cacggtgacg ccggagattg gcggcaccag tgagccaaac agcaaaatca ctatctttgt
     2761 gaatggcgtt gaaaaagcga ttgcttatac gacaggcgca ggacactggg gcgtagtatt
     2821 acccgctttg ggtaatgacg gtaattatga attaacgttt aaagttgaag acgttgccgg
     2881 caatatcaga gagtttggtc cgcagaatgt gatactggat acggtaattt cgccgttaac
     2941 cgtggtatta cgcgaagctg atgacagtgg caaagttggc gactggatca ccaataaatc
     3001 tcatgtcacc atcgatggta ctgccgaagc cggaagtact ttgaccatca ggaatccgca
     3061 gggagtggtt attgctaccc tggtggtagg caatgatggt cgatggagcg cagaattaga
     3121 tctgcgtgaa ggtagtaatg cctttgtcgt ggtatcggaa gataaagcgg gcaacggcca
     3181 acaaaaagat attctgatag aacatgatac gcagattgaa atcagcgata tttcattaag
     3241 tcgggatact aatagcggtg ataaatatga tctgattacc aataataagt ctccggtact
     3301 ggttgccatg accgatcccg gcgcgacggt acaggtttat attaatggtg tgttacaagg
     3361 cacagtagag gcgagttcgt caggtaatat tagctatacc atgccggcaa atagcgccga
     3421 cggcgagtat caggtgcaat ttgttgctac ggatactgct ggtaaccggg ttgaatctgc
     3481 gattacgacc gtgacaatcg attctcaaat tgctgtcttt gatattgatg aagattcatt
     3541 accggccctc tctaataacc gggcgttgtc agtctcaggc gtcggggagg ctggttctca
     3601 ggtcagcatc tttgtcgatg gtaaattagt caacgttgtt atggttgagg ctgatggctc
     3661 atggcgcgcg ccgatactgc tgcaagatga tggtacgttt aatattcatt tcagcattac
     3721 tgacgttgct ggcaacactc aagtaagcaa gaattacagt gtggatgtcg attcatcaac
     3781 cgacttccca acgctcaacc ttgaagatgc gagcaactct ggttcacttg acgatctgat
     3841 tactaatcac aacaagcctg tgttagttgg caccgcagaa gcgggagcca caatccatat
     3901 ttatgtggat gaaaagatcg tggcaaatgt gcttgtgctt gaagatggaa cctggtccta
     3961 tcagtttgat aatgcgttaa aagatggtga atattctatc cgtgtggttg ccgaagaccc
     4021 ggcaggtaat acggcagaat cgcctcgctt actcgtcacg atagatacca gtacgtttat
     4081 cgataatcct gctatggtgg caggttctga taacggtatt ttcagtaatg atagtataac
     4141 gagtcagacc cggcctacgt ttagtatttt tggagaaatg aaccagagtg ttcagatttt
     4201 cattgatggg gtgttagtcg atacgatcac ggtgacggac agaaatcaag tttatcgacc
     4261 tgagtcaccg ttgggcgatg gttcccatag catttattat gttatcaccg ataaagcagg
     4321 caacacggct acctcgaaaa cgctaaactt tactatcgat acctttaata cgacgcctgt
     4381 cgccattgat tctatcggtg gacaaacgtt agcagagatg accggtagtg atggcaaaat
     4441 atatataacg gacacgacgc gtaacttatt gtttagtggc agtgccgagc ccaatagcaa
     4501 aatagaaatc attattaatg gcttaaatgt gggggaagtt tgggttaatg aaaaaggcca
     4561 ctggcagatg ccggtgaacc cgctttattt cacagaaggc caactggata tcactgttaa
     4621 atctacggac cgtgctggta acgtaaatca ggaaaagtat tccatttggg tcgatacgca
     4681 tatccaggta tttaccagcg agcttgatga caataaatca tcatcgaaaa cggactggtg
     4741 gagtaatagc tccactatta ccatgagagg tatgggggaa attggcgcta cggtatcatt
     4801 aatcgtggca ggggtcacgc tggcaaccgc tgtcgttgcg gctaatgggc agtgggaatt
     4861 atcgaccgat cagcttccgg aagggaaata cgatatcact ttgagtattg aggataacgc
     4921 aggcaaccgt aaggaagagg tacatgaaat atttattgat cgaacgccgc caaacgctcc
     4981 ggtcgtaact tattcagaca ttgtcaacga tctaattatt atgcagggaa cggcggaagc
     5041 caaatctcag ctaataataa ccgatagtaa tgggaatact tatacgttaa ccgttcctga
     5101 taatggtaaa tggagtatgg cgatcccgta tccatcggaa gggaagttta ccattacgag
     5161 tgtggatgcg attggtaacc ggagtgatga tgtccctctc gatatcatga aagaggttcc
     5221 cgttatttca ttatctccag actcagacag tggtacggtg ggcgataata ttacgcgcga
     5281 taagcaacct acctttatta tcgggaatct ggaaagcgat gttgtggtcg ttcaggtcga
     5341 tatcaatggg acagtatata atgctgaaaa aaatgccgat ggcgtttggt tctttacgcc
     5401 aggtacaccg ttagctgatg gttcctatac gatatcggta atcgcaagcg atgccgcggg
     5461 taatcagaaa aactcgttac ccattaccgt tacgatcgac agtacgctga cggtgccgga
     5521 gattgcgttg gcagcaggtg aagacaatgg cgtttcagac agcgataacg tgacgaatca
     5581 cacccagcct aagttcacgc tgcagcatat tgatgctgat gtgaccgggg tgaccgtaaa
     5641 cgtgacgcat aacggcgtga cagacaccta tcaggcgacg caaggcgcgg atggctggac
     5701 cttcacgccg ccagccgcct ggaatgatgg tacctacacg ctgagcgtga cggtggtgga
     5761 tcgcgcgggg aactcacagc aatctgcttc gctagcggtg acggttgact caacggtgac
     5821 ggtaacagcg gatagccagc atgacgatgc gagcgatgac gccacgccaa cagcggttac
     5881 tccaccggag tctgaaacag tgaatgccga aagcgatacg catcttcgta cagtgccgtc
     5941 tgcggcggaa gaaagcgtgg tgaaggagac ggcctatagt attacattgt taaacgctaa
     6001 ctctggggat gaaatagatc gttcaattag tcagacacct tcttttgaaa tatcagtacc
     6061 tgagaatatt gttaatgtca gtgttatgtt tgaaggagaa gagtttactc tgccgataac
     6121 taaccagaaa gcaatattcg aagttccgct atctttggaa gatggtgaat atactatgga
     6181 cgtgaaattc attgataagg acgatgattt cctgattaag gaaaaaacat tctcagtcga
     6241 tcactcctcg gcggatattg tgaacgcaat gaatgcaaga ggaaagaccg aggatgatat
     6301 taatgattcc ccttccacga gttctgtagg gcacaacaat aacggcgcta ttgatgtttt
     6361 cgccgttaat gaagttacgc tacctgtaga taatcaagaa gaacacgcat aataacggag
     6421 gcccctcacc tttgggtgag ggggtttact tatggataaa aaactagaac cttattattt
     6481 aagtgcggaa acggcattat ctatagtgtc taaaaaattc aacataaaaa ttgacatcaa
     6541 agaggatgat ataaatttaa gatttaaaaa gtacgacaga aataacactg atgactctat
     6601 acaaatgaag aatttctttt tg
//
LOCUS       DAJVBX010000223         6489 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.223, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000223 DAJVBX010000000
VERSION     DAJVBX010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 6489)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6489)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6489
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.223"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(68..1786)
                     /gene="proS"
                     /locus_tag="OPV72_003979"
     CDS             complement(68..1786)
                     /gene="proS"
                     /locus_tag="OPV72_003979"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HCR9916149.1"
                     /translation="MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLP
                     TGLRVLKKVENIVREEMNNAGAIEVSMPVVQPADLWQESGRWEQYGPELLRFVDRGER
                     PFVLGPTHEEVITDLVRNELSSYKQLPLNFFQIQTKFRDEVRPRFGVMRSREFLMKDA
                     YSFHTSQESLQETYDAMYAAYSRIFSRMGLDFRAVQADTGSIGGNASHEFQVLAQSGE
                     DDIVFSDVSDYAANIELAEAIAPQTPRAAATQEMTLVDTPNAKTIAELVEQFNLPIEK
                     TVKTLLVKAVKDSKSPLVALLVRGDHELNEVKAEKLPHVASPLTFATEEEIRAVINAG
                     PGSLGPVNMPIPVIIDRTVAAMSDFAAGANIDGKHYFGINWDRDVATPVVADIRNVVA
                     GDPSPDGQGTLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTR
                     VVAAAIEQNFDERGIVWPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVL
                     MDDRKERPGVMFADMELIGIPHTIVIGDRNLDNDDIEYKYRRSGEKSLIKTGDIVDYL
                     VKAIKG"
     gene            complement(1897..2604)
                     /gene="tsaA"
                     /locus_tag="OPV72_003980"
     CDS             complement(1897..2604)
                     /gene="tsaA"
                     /locus_tag="OPV72_003980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase
                     TrmO"
                     /protein_id="HCR9916150.1"
                     /translation="MSSFQFDQIGVIRSPYKEKFAVPRQPGLVKSACGELHLIAPYNQ
                     ADAVRGLEAFSHLWVLFVFHQTMDGGWRPTVRPPRLGGNARMGVFATRSTFRPNPIGM
                     SLVALKGIECRKESVILKLGSLDLVDGTPVVDIKPYLPFAEALPDAAASYAQQAPIAE
                     MPVSFTAEVAQQLTTLERRYPQLRTFICDVLAQDPRPAYRKGEETGKTYAVWLHDFNV
                     RWRVVNTGFEVFALEPR"
     gene            complement(2601..3005)
                     /gene="rcsF"
                     /locus_tag="OPV72_003981"
     CDS             complement(2601..3005)
                     /gene="rcsF"
                     /locus_tag="OPV72_003981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rcs stress response system protein RcsF"
                     /protein_id="HCR9916151.1"
                     /translation="MRALPICLLALMLGGCSMLSRSPVEPVQSTATPPKAEPEKPKAP
                     RAAPVRIYTNAEDLVGKPFRDLGEVSGESCQATNQDSPPNIPTARKRMQINASKMKAN
                     AVLLHSCEITSGTPGCYRQAVCIGSALNISAK"
     gene            complement(3124..3939)
                     /gene="metQ"
                     /locus_tag="OPV72_003982"
     CDS             complement(3124..3939)
                     /gene="metQ"
                     /locus_tag="OPV72_003982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter substrate-binding
                     lipoprotein MetQ"
                     /protein_id="HCR9916152.1"
                     /translation="MAFKFKTFAAVGALIGSLALAGCGQDEKDPNHIKVGVIVGAEQQ
                     VAEVAQKVAKEKYGLDVELVTFNDYVLPNEALSKGDIDANAFQHKPYLDQQIKDRGYK
                     LVSVGKTFVYPIAGYSKKIKSLDELKDGSQVAVPNDPTNLGRSLLLLQKVGLIKLKDG
                     VSLLPTSLDIVENPKNLKIVELEAPQLPRSLDDAQIALAVINTTYASQIGLTPAKDGI
                     FVEDKDSPYVNLIVTREDNKDAENVKKFVQAYQSDEVYEAANKVFNGGAVKGW"
     gene            complement(3978..4631)
                     /gene="metI"
                     /locus_tag="OPV72_003983"
     CDS             complement(3978..4631)
                     /gene="metI"
                     /locus_tag="OPV72_003983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease MetI"
                     /protein_id="HCR9916153.1"
                     /translation="MSEAMMWLLVRGVWETLAMTFVSGFFGFVIGLPVGVLLYVTRPG
                     QIMENARLYRSLSAVVNIFRSIPFIILLVWMIPFTRIIVGTSIGLQAAIVPLTVGAAP
                     FIARIVENALLEIPAGLIEASRAMGATPLQIVRKILLPEALPGLVNAATITLITLVGY
                     SAMGGAVGAGGLGQIGYQYGYIGYNATVMNTVLVLLVVLVYLIQLSGDRIVRAVTHK"
     gene            complement(4624..5655)
                     /gene="metN"
                     /locus_tag="OPV72_003984"
     CDS             complement(4624..5655)
                     /gene="metN"
                     /locus_tag="OPV72_003984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014168731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein
                     MetN"
                     /protein_id="HCR9916154.1"
                     /translation="MIKLSNITKVFQQGARTIQALNNVSLHVPAGQIYGVIGASGAGK
                     STLIRCVNLLERPTEGSVMVGGQELTTLSESGLTKARRQIGMIFQHFNLLSSRTVFGN
                     VALPLELDNTPKEEIKRRVTELLDLVGLGDKHDSYPANLSGGQKQRVAIARALASNPK
                     VLLCDEATSALDPATTRSILELLKDINRRLGLTILLITHEMDVVKRICDCVAVISNGE
                     LIEQDTVSEVFSHPKTPLAQKFIQSTLHLDIPEDYQARLKASPETDSVPMLRMEFTGQ
                     SVDAPLLSETARRFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQEETQAAIAWLQDHH
                     VKVEVLGYV"
     gene            5845..6411
                     /gene="gmhB"
                     /locus_tag="OPV72_003985"
     CDS             5845..6411
                     /gene="gmhB"
                     /locus_tag="OPV72_003985"
                     /EC_number="3.1.3.82"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-glycero-beta-D-manno-heptose 1,7-bisphosphate
                     7-phosphatase"
                     /protein_id="HCR9916155.1"
                     /translation="MAKSVPAIFLDRDGTINVDHGYVHEIDAFEFIDGVIDAMRELKK
                     MGYALVVVTNQSGIARGKFTEAQFETLTEWMDWSLADRDVDLDGIYYCPHHPQGSIEE
                     FRQVCDCRKPHPGMLISARDFLHIDMAASYMVGDKLEDMQAAAAANVGTKVLVRTGKP
                     VTAEAENAADWVLNSLADLPSAIKKQQK"
BASE COUNT         1578 a         1705 c         1679 g         1527 t
ORIGIN      
        1 gcctcgcagg gtgcgaggcc tttacatatc tgccggatgg cgccgggcaa tcccaacaaa
       61 atgtcgttta gcctttaatc gccttgacca gataatcaac gatatcgccg gttttaatca
      121 gcgatttttc accgctacga cggtatttat actcaatatc gtcgttatcc aggttgcgat
      181 cgccaatcac gatagtatgt ggaataccaa tcagctccat atcggcaaac atcacgcccg
      241 ggcgctcttt acgatcgtcc atcagcactt caatgccctg cgcgcgcaat tcgctgtaca
      301 gcttttccgc cagctcctgc acacggaagg atttgtgcat attcatcggc agaatagcga
      361 cctggaaagg tgcaatggcg tcaggccata caatgccgcg ctcgtcaaag ttctgctcga
      421 tagccgcggc aacgacacgt gttacgccga taccatagca gcccattgtc aggatctggt
      481 tacggccatc ttcaccctga acggaggctt tcagcgcttc tgagtacttg gtacctaact
      541 ggaagatgtg acccacttcg ataccgcgtt tgataagcaa cgttccctga ccatccggac
      601 tcggatcgcc ggcgactacg ttacggatgt cggcaacaac aggcgtcgcc acatcgcgat
      661 cccagttaat accaaagtag tgtttaccgt cgatgttagc gccagcggca aaatcgctca
      721 tggcggcaac ggtacgatcg atgatgaccg gaatcggcat attgaccggg ccgagggagc
      781 cagggccggc attaattacg gcgcgaatct cttcttcagt agcgaaggtc agcgggctgg
      841 caacgtgcgg cagtttttcc gctttaactt cattcagttc atgatcgccg cgaaccagca
      901 gagccaccag cggagacttg ctgtctttca ccgctttcac cagcagcgtt tttaccgttt
      961 tttcaattgg caggttgaat tgttccacca gctccgcgat ggttttggca tttggcgtat
     1021 cgaccagagt catttcctgc gtcgccgctg cgcgcggtgt ttgcggcgcg atagcttctg
     1081 ccagttcaat gttagccgcg taatcagaaa catcagagaa aacgatatcg tcttcgccgc
     1141 tttgcgccag cacctggaat tcatgcgagg cgttgccgcc gatagaaccg gtatcggcct
     1201 gtaccgcgcg gaaatccagc cccatacggc tgaagatacg gctatacgcg gcgtacatgg
     1261 cgtcataggt ttcctgcaac gactcctgag aggtgtggaa agagtaagca tctttcatca
     1321 ggaattcgcg cgaacgcatc acgccaaagc gcggacgcac ttcatcacgg aatttggtct
     1381 ggatttggaa gaagttcagc ggcaactgct tataagagct gagttcatta cgcaccaggt
     1441 cggtgataac ttcttcgtgg gtcgggccga gtacgaacgg acgctcgcca cggtcgacaa
     1501 aacgcagcag ttccggaccg tactgttccc aacgaccact ctcttgccac aggtcggctg
     1561 gctgaacgac tggcatcgac acctcgatag caccggcgtt gttcatctct tcacgcacga
     1621 tgttttcgac ttttttcagg acgcgcaggc cggtcggcag ccaggtatat aacccggagg
     1681 cgagcttgcg gatcatcccg gcgcgcagca tcagctggtg gctgataacc tcggcgtcgg
     1741 caggtgtctc cttcagagtg gagagcaggt attggctagt acgcatgttg ttacggttcc
     1801 agttgaacga tcgaacaggc tcaatgtgag cctgatacaa aaaaagtgat ttagtttacc
     1861 agcgtgcaag agatgtcaaa agagaagggc gtgaaattac cgtggttcca gcgcaaacac
     1921 ttcaaatccg gtgttaacca cacgccagcg cacgttaaaa tcatgcagcc agacggcata
     1981 ggttttgccc gtctcttcac ccttacgata agccgggcga ggatcttgcg ccagcacatc
     2041 gcaaataaat gtccgtagct gcggataacg cctttccagc gtcgtaagct gttgagccac
     2101 ttcagcggta aaactcacag gcatttcagc tatcggcgcc tgttgcgcat agctggcggc
     2161 ggcgtccggt aaggcctcgg caaacggtaa atacggtttg atatccacca ccggcgtgcc
     2221 atccaccaga tccagactgc ctaatttcag aattacgctc tctttccggc actcgatacc
     2281 ttttagcgca acgagcgaca tgccaatcgg attggggcgg aacgtggagc gcgtggcaaa
     2341 aacgcccatt ctggcgttac cgccaagacg gggcggacga actgttggcc gccagccgcc
     2401 gtccatcgtc tgatgaaaaa cgaaaagcac ccacaaatgg ctgaacgctt ccaggccgcg
     2461 aacggcatcg gcctggttgt aaggcgctat cagatgcagt tcgccgcagg cgcttttgac
     2521 cagaccaggc tggcgcggaa cggcgaattt ttctttatag ggggagcgaa taacgccgat
     2581 ttgatcaaac tgaaagctgc tcatttcgcc gaaatattca gggcggaccc gatacaaacc
     2641 gcctgacggt agcagcctgg cgtgccgctg gtaatttcac agctgtgcag caggacggcg
     2701 ttggctttca ttttagatgc attaatctgc atacgcttgc gcgcagttgg aatgttaggc
     2761 ggagagtctt gatttgtcgc ctggcaggat tcgccgctaa cctcgccaag atcgcggaaa
     2821 ggtttgccga ctaagtcttc agcattggtg taaatcctga cgggagcggc acgcggcgct
     2881 ttaggtttct ccggctccgc ttttggcggg gttgcggtgc tttgaacagg ttcaacaggg
     2941 gatctgctta gcatggaaca accgcccagc atgagtgcca ataaacagat cggtaaagca
     3001 cgcataatat ttcctcaatg aatgttctaa ttgccagata ttgaatcagg agcttgcata
     3061 aatgacaaga cgggcaatag cccgtcctga ataatattac agattgtgga atcagcctaa
     3121 aacttaccag cctttcaccg cgccgccatt aaaaacttta tttgcggctt cgtacacttc
     3181 atcagactgg taagcctgaa cgaatttttt cacattctcg gcgtctttgt tatcttcacg
     3241 cgtcacgatc aagttaacgt acggagaatc tttatcttca acgaagatac cgtctttcgc
     3301 tggcgtcagg ccaatctggc tggcgtaagt cgtattgatg accgctaacg cgatctgagc
     3361 gtcatccagc gaacgcggca actgcggcgc ttccagctca acaattttca gatttttcgg
     3421 gttttcgacg atatccagcg aggtaggaag cagactgacg ccgtctttca gtttaatcag
     3481 ccctactttt tgcagcagca gcagggaacg accaaggttg gtcgggtcgt taggcacagc
     3541 gacctgggaa ccgtccttga gctcatccag agatttgatt tttttggaat atcctgcaat
     3601 gggatagaca aaagtcttac caacggaaac cagtttgtag ccgcgatctt tgatttgctg
     3661 atccagatac ggtttgtgct ggaaggcatt ggcatcgata tcgcctttgc tcagcgcttc
     3721 attaggcaga acataatcat taaaggtcac caattccacg tccaggccgt atttttcttt
     3781 cgcgactttc tgcgcgactt cggcaacttg ctgctctgcg ccaacgatta cgccgacttt
     3841 aatatgattc ggatcttttt catcctgacc gcaacccgca agtgccagag aaccaatcag
     3901 agcacccact gccgcaaagg ttttgaattt gaacgccatg cttatttcct taatgagtat
     3961 ttgtgttgtg tttaacgtta cttatgcgtg acagccctga cgatgcgatc gccggataac
     4021 tgaattaaat aaaccagaac gacaagtaat accagcaccg tattcatcac ggtagcattg
     4081 tatccaatat aaccgtactg atagccgatt tgaccgaggc cgcctgcgcc gacggcgccg
     4141 cccattgcgg agtaaccgac cagggtgatt agtgtaatgg ttgccgcatt caccagacca
     4201 ggcagcgctt ccggtaaaag gattttacgt acaatttgca gcggcgtggc gcccatcgct
     4261 cgcgaggctt caatcagccc ggcagggatc tctaacaacg cattttccac tatacgggcg
     4321 ataaaaggcg cggcgccgac ggtcagcggt acaatcgcgg cctgcaaacc aatggaggtg
     4381 ccgacaatta ttcgggtaaa aggaatcatc cacaccaaca ggatgataaa gggaatcgag
     4441 cggaaaatat tgaccaccgc agagagggag cgatacagcc tggcgttctc cataatctgc
     4501 cccgggcgcg taacatacag caatacgcca accggcaggc caatcacgaa accgaagaaa
     4561 ccggagacaa aggtcatcgc cagcgtttcc cagacgccac gaaccagtaa ccacatcatt
     4621 gcctcagaca taacccagta cctctacttt cacatggtga tcctgcagcc aggcaattgc
     4681 ggcttgcgtc tcttcttgtg tgccgtgcat ttccgttagc ataatgccga acttcacacc
     4741 gcccgcgtaa tccatctgtg cgctgataat attattgttc acgttgaaac gacgcgcggt
     4801 ttcagaaagc agcggggcat ccacagactg tccggtgaac tccatgcgca gcatcggcac
     4861 gctgtcagtt tccggcgacg ctttcaaacg cgcctggtaa tcttccggaa tgtccagatg
     4921 cagagtggac tgaataaact tctgcgccag cggcgtttta ggatgcgaga agacttcgct
     4981 gaccgtatcc tgctcaataa gctcgccatt actgatgacg gcaacgcagt cgcagatacg
     5041 ttttacgaca tccatttcat gagtgataag cagaatcgtc aaccccagac gacggttgat
     5101 atctttcagc aattccagaa tcgaacgggt cgtcgcggga tcaagcgcgc tggtggcttc
     5161 atcgcacagc aacacttttg gattactggc taacgcgcgg gcaatcgcga cacgctgttt
     5221 ctgaccgccg gaaagatttg ccggatagct gtcgtgcttg tcgccaagac cgactaaatc
     5281 cagcagctct gtgacacggc gtttgatctc ttcctttggt gtgttatcca gttccagcgg
     5341 caacgcgacg ttgccaaaca cggtacggga agagagcagg ttaaaatgtt ggaaaatcat
     5401 gccgatttga cggcgagctt tggtcaaccc ggactctgaa agcgttgtca gctcctgacc
     5461 gcctaccatt acgcttcctt cagtaggacg ttcaagtaag tttacgcagc gaatgagcgt
     5521 acttttaccg gcgccggagg cgccgatgac gccgtaaatt tgtccggcag ggacatgcag
     5581 gctgacattg ttcagcgcct gaatggtgcg cgccccctgc tggaacactt tggtaatatt
     5641 cgaaagttta atcattgatt ctttattatc gtaatgaaat gagcggaggc attttcgtct
     5701 gcctaatacg gtcaacgccg tcaacagaat ggatgttaag gcatccagac gtctaaatca
     5761 atcaggcttt atacgatgag cactttcttg cctgctgaaa catgcgatac tagcgccact
     5821 tgctttactc aggagctata aaaggtggca aagtctgtac ccgcaatttt tctcgaccgt
     5881 gacggcacca ttaatgtgga tcacggctac gtacatgaaa tcgatgcatt tgagtttata
     5941 gacggcgtta ttgacgcgat gcgcgagcta aaaaaaatgg gctatgcgct ggtggtggtg
     6001 acgaaccagt ccggaatcgc gcgcggcaaa ttcactgagg cgcagtttga aacgttaacc
     6061 gaatggatgg actggtcgtt ggcggatcgc gatgttgatt tggacggcat ctattattgt
     6121 cctcaccatc cgcagggcag catagaagag ttccgtcagg tatgtgattg ccgcaagccg
     6181 catccaggaa tgcttatctc ggcgcgtgat ttcctgcata tcgatatggc ggcttcttat
     6241 atggtgggag acaagctgga agatatgcag gcggcagcgg cggcaaatgt cgggacaaaa
     6301 gtgctggtgc gtacgggcaa accggtcacg gcagaagcag aaaacgcggc ggactgggtg
     6361 ttaaacagcc ttgctgacct gccatcagcg ataaaaaagc agcaaaaata agcgttatgg
     6421 ataaaagatg agcggttaaa acaaaaatgc atttttccgc ttgtcttcct gaaccgactc
     6481 cctataatg
//
LOCUS       DAJVBX010000224         6480 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.224, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000224 DAJVBX010000000
VERSION     DAJVBX010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 6480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6480
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.224"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            73..2919
                     /gene="rcsC"
                     /locus_tag="OPV72_003986"
     CDS             73..2919
                     /gene="rcsC"
                     /locus_tag="OPV72_003986"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     RcsC"
                     /protein_id="HCR9916156.1"
                     /translation="MKYLASFRTTLKVSRYLFRALALLIWLLIAFVSVFYIVNALHQR
                     ESEIRQEFNLSSDQAQRFIQRTSDVMKELKYIAENRLTAENGVMSSRARDDKMVVPDF
                     EPLFADSDCAAMGSAWRGSLESLAWFMRYWRDNFSAAYDLNRVFLIGSDNLCMANFGL
                     REMPVERDDALKALHERIMKYRNAPQEESGNNLFWISQGARQGVGYFYALTPVYLANR
                     LQALLGVEQSIRMENFFTPGSLPMGVTIIDENGHSLISLTGPDGIIKAEPRWMQERSW
                     FGYTPGFRELVLKKSLPPSSLSIVYSVPVDLVLERIRILILNAILLNVLVGAGLFTLA
                     RMYERRIFIPAESDAQRLEEHEQFNRKIVASAPVGICILRTIDGVNILSNELAHTYLN
                     MLTHEDRQRLTQIICGQQVNFVDVLTSNNTNLQISFVHSRYRNENVAICVLVDVSTRV
                     KMEESLQEMAQAAEQASQSKSMFLATVSHELRTPLYGIIGNLDLLQTKELPKGVDRLV
                     TAMNNSSSLLLKIISDILDFSKIESEQLKIEPREFSPREVMNHITANYLPLVVRKQLG
                     LYCFIEPDVPVSLNGDPMRLQQVISNLLSNAIKFTDIGCIVLHVRCDGDYLSIRVRDT
                     GVGIPAKEVVRLFDPFFQVGTGVQRNFQGTGLGLAICEKLISMMDGDISVDSEPGMGS
                     QFTLRIPLYGAQYPVKKSVEGLAGTCCWLAVRNTSLCQFIETSLARSGVHTQRYEGQE
                     PAADDILIVDDALEHTWQGRAAVVFCRRHIGIPLERAPGEWVHSVASVHELPALLARI
                     YSIELDSEALSSALPTTDKTADSNDDMMILVVDDHPINRRLLADQLGSLGYQCKTAND
                     GVDALNVLSKNAIDIVLSDVNMPNMDGYRLTQRIRQLGLTLPVVGVTANALAEEKQRC
                     LESGMDSCLSKPVTLDALKQTLAVYAERVRKTRA"
     gene            complement(3022..3672)
                     /gene="rcsB"
                     /locus_tag="OPV72_003987"
     CDS             complement(3022..3672)
                     /gene="rcsB"
                     /locus_tag="OPV72_003987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RcsB"
                     /protein_id="HCR9916157.1"
                     /translation="MNNMNIIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINN
                     LPKLDAHVLITDLSMPGDKYGDGITLIKYIKRHFPSLSIIVLTMNNNPAILSAVLDLD
                     IEGIVLKQGAPTDLPKALAALQKGKKFTPESVSRLLEKISAGGYGDKRLSPKESEVLR
                     LFAEGFLVTEIAKKLNRSIKTISSQKKSAMMKLGVENDIALLNYLSSVTLSPTDKE"
     gene            complement(3689..6358)
                     /gene="rcsD"
                     /locus_tag="OPV72_003988"
     CDS             complement(3689..6358)
                     /gene="rcsD"
                     /locus_tag="OPV72_003988"
                     /EC_number="2.7.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase RcsD"
                     /protein_id="HCR9916158.1"
                     /translation="MSQSDTTVSTRFSLLPGSITRFFLLLIIVLLVTMGVMVQSAVNA
                     WLKDKSYQIVDITHAIHKRVDTWRYVTWQIYDNIAATTTPSTGEGLQETRLKQDVYYL
                     EKPRRKTEALIFGSHDSATLEMTQRMSTYLDTLWGAENVPWSMYYLNGQDNSLILIST
                     LPLKDLSSGFKESTIGNIVDSRRAEMLQQANALDERESFSSLRKLAWQNGHYFTLRTT
                     FNQPGHLATVVAFDLPINDLIPPGMPLDSFRIEPDATQTTGRSSEKEAPDSVTISFNG
                     SKIEISSALNSTGMRLIWQVPFGTLLLDTLQNILLPLLLNIGLLALALFGYATFRHQP
                     GRSTESTSGNAANNELRVLRAINEEIVSLLPLGLLVYDQEGNRTVISNKIADHLLPHL
                     NLQNITSMAEQHQGVIQATINNELYEIRLFRSQIAPRTQIFIIRDQDREVLVNKKLKQ
                     AQRLYEKNQQGRAAFMQNISNTLKEPVRQLAVNAAAVTTPESLKLADQADVLVRMIDE
                     IQLANMLENDAWKSEATLFSLQDLIDEVVPEVLPAIKRKGLQLLINNHLSGNDERWGD
                     RDALRRILLLLIQYAVTTTAMGKITLEVEQDESIAERLTFRILDTGEGVTLNEIDNLH
                     FPYMNETQGDRYGKANPLTFWLCNQLARKLGGHLNIKARETLGTRYTVHVKMLPHDQH
                     TQVEERLLDDVSVMVDVTSNEVRAIVLRQLENWGATCITPDERQISQEYDLFLTDNPS
                     NLTASGLLLSDDESGVRKIGPGQLRVNFNMSNAMQEAVLQLIEEQLAQEEIPASPLGG
                     DENAELHASGYYALFVDTVPDDVKRLYTEAATSDFAALAQTAHRLKGVFAMLNLVPGK
                     QLCVTLEHLIREKDAPGIEKYISDIDAYVKSLL"
BASE COUNT         1457 a         1626 c         1754 g         1643 t
ORIGIN      
        1 cgttgcgggc tacgtcattt accgctacct tagtcacact ctatttacat cctgaggcgg
       61 agcttcgccc ctttgaaata ccttgcttcc tttcgaacta cgctgaaagt ctcgcgctac
      121 ttattcagag cgttagcgtt actcatttgg ctcttaatcg cctttgtttc ggtgttttac
      181 atcgtcaatg ccctgcacca gcgggagtct gaaattcgtc aggagttcaa ccttagctcc
      241 gatcaggcgc agcgttttat ccagcgcacg tcggatgtga tgaaagagct caaatatatc
      301 gccgagaacc gtttaacggc ggaaaacggc gtcatgtcgt cgcgtgcgcg tgatgacaaa
      361 atggtggtgc cggattttga accgctattc gccgactcag actgtgcggc gatgggctcc
      421 gcctggcgcg gctcgctgga gtcgctggcc tggtttatgc gttactggcg cgacaacttt
      481 tcagcggcgt atgatcttaa ccgcgttttc ctgattggca gcgataacct ctgtatggcg
      541 aatttcggcc tgcgtgaaat gcccgtggag cgcgatgatg cgttaaaagc gttacatgag
      601 cggattatga aataccgcaa cgcgccgcag gaagaaagtg ggaataacct tttctggata
      661 agccagggcg cgcgtcaggg cgtgggctac ttttatgcgc tgacgccggt gtatctggcc
      721 aatcgtctgc aggcgctgct gggcgttgag cagtccatcc gtatggaaaa ttttttcacg
      781 cccggcagtt tgccgatggg cgtcactatt attgatgaga acggccattc gctgatttcg
      841 ttgaccggtc ctgacggcat tattaaagcg gagccgcgct ggatgcagga gcgttcctgg
      901 tttggttata cgccaggttt tcgcgaactg gtactcaaaa aaagcctgcc gccatcctcg
      961 ctcagtattg tctattctgt gcctgtagat ttagtcctgg agcgtattcg tattcttatc
     1021 ctgaacgcta tcctgctgaa cgtgctggtg ggcgcagggc tgtttacgct tgcgcggatg
     1081 tatgagcggc gaattttcat tccggcggag agcgatgccc agcgtctgga agaacatgaa
     1141 cagttcaacc gtaaaatcgt tgcctccgcg ccggtgggga tctgtattct gcgcactatt
     1201 gatggtgtca atattctgag taacgaactg gcgcacacct acctgaacat gctcacgcat
     1261 gaagacagac agcgcctgac gcaaatcatt tgcggccagc aggtcaactt tgttgatgta
     1321 ttgaccagca ataataccaa tttgcaaatt agcttcgtcc attcccgcta tcgtaatgaa
     1381 aacgtcgcga tttgcgtgtt ggtagatgtg agtacgcgcg tcaaaatgga agagtcgctg
     1441 caagagatgg cgcaggcggc ggagcaggca agccagtcta aatccatgtt ccttgcaacg
     1501 gtcagccatg aattgcgcac accgctgtac ggtatcatcg gcaatctcga tctgctgcaa
     1561 accaaagagc tgccaaaagg cgtggatcgt ctggtcacgg cgatgaataa ctcctccagt
     1621 ctgttgctga aaattatcag cgacattctc gacttctcga aaattgagtc ggaacagcta
     1681 aagattgagc cgcgcgaatt ttcaccgcga gaggtgatga accatatcac cgccaattat
     1741 ctgccgctgg tggtgcgtaa gcaactcggc ctgtattgtt ttattgagcc tgacgtgccg
     1801 gtatcgctga acggcgaccc gatgcgttta cagcaggtta tttcaaacct gttgagcaac
     1861 gccattaagt ttaccgatat tggctgcatc gtgctgcatg tgcgctgtga tggggattat
     1921 ctcagcattc gcgtgcggga taccggggtt ggtattccgg caaaagaggt ggttcgcctg
     1981 ttcgatccct tcttccaggt gggaaccggc gtacagcgta actttcaggg gaccggtctg
     2041 gggctggcga tttgcgaaaa attgatcagc atgatggacg gcgatatttc cgtcgattcg
     2101 gagccgggca tgggaagcca gtttacgttg cgcatcccgc tttatggcgc gcaataccct
     2161 gtgaaaaaga gcgtggaagg actcgccgga acctgctgtt ggctggcggt gcgcaatact
     2221 tctttgtgcc agtttattga gaccagtctg gcgcgtagcg gcgttcatac gcagcgttat
     2281 gaagggcaag aacccgccgc agacgatatt ttgattgtcg atgacgcgct ggagcatacc
     2341 tggcagggga gggcggcggt cgtcttttgc cgccgtcata tcgggattcc attggaaaga
     2401 gcgcctggcg agtgggtgca tagtgtggcg tcggtgcatg agttgcccgc gctgttggcg
     2461 cgtatctata gtattgagct ggatagtgaa gcgctttcca gcgcattgcc gacgacggat
     2521 aaaaccgcag attcaaatga cgacatgatg attctggtcg ttgacgatca tccgatcaat
     2581 cgccgcttgc tggccgatca actgggatcg ctggggtatc agtgtaagac agccaatgat
     2641 ggcgtggacg ctctgaatgt gctgagtaaa aatgctatcg atattgttct gagcgatgtg
     2701 aacatgccga acatggacgg ctatcgcctg acgcagcgta tccgtcagct tgggctgacg
     2761 ctgccggtcg tcggcgtgac ggcgaacgcg ctggcggaag agaaacaacg ttgcctggag
     2821 tccggtatgg atagctgttt gtcgaagcct gtgacgctgg atgcgttgaa acagacgctg
     2881 gcggtgtatg ccgagcgggt acgtaaaacg cgggcataaa aaatgccgga tggcggcgtc
     2941 gcctgtccgg cctgtaaaag atgagtcgac tggtaggcct gataagcgta gcgccatcag
     3001 gctgggtaac ataaaagcga tttattcttt gtctgtcgga ctcagggtga cggaagagag
     3061 atagttgagc agcgcgatat cattctctac gcccagtttc atcatcgccg atttcttctg
     3121 gctgctgatg gtcttaatgc tgcggttgag cttcttggcg atttcggtga ccaggaagcc
     3181 ctcggcgaac aggcgtaata cttcgctctc ttttggcgac aggcgcttat cgccgtaacc
     3241 gcctgcgctg attttctcca gcagacgaga aacgctttcc ggggtgaatt ttttgccttt
     3301 ttgcagcgcg gccagcgcct taggcagatc ggttggcgca ccctgtttga gtacgatccc
     3361 ttcaatatca agatccaaca cggcgctcag gatcgccgga ttgttgttca tggtcagaac
     3421 gataatagac aggctcggaa aatgacgctt gatgtacttg atcaaggtga tcccatcgcc
     3481 gtatttatct cccggcatgg agaggtcagt gatcaacaca tgcgcatcta atttcggcag
     3541 gttgttgatc aatgctgtgg aatcttcaaa ttcgccgaca acattcaccc actcgatttg
     3601 ttcaagtgat ttgcgaatac cgaacagtac aatcgggtgg tcatcggcaa taattatgtt
     3661 catattgttc atgtattggg ctactttgct acagcaagct tttgacgtag gcgtcaatgt
     3721 cgctgatata tttttctata cctggagcat ctttctcacg aatcagatgt tccagcgtta
     3781 cacataactg cttgccgggt accagattaa gcatggcaaa cacccctttc aggcggtggg
     3841 ccgtttgggc cagcgcagcg aaatcgctgg ttgccgcctc agtatacaac ctcttaacat
     3901 catccggtac tgtgtctaca aatagcgcat aatagccgct ggcatgaagc tcggcatttt
     3961 catctccgcc gagcggggag gcgggaatct cttcctgcgc cagctgctct tcgataagtt
     4021 gtagtacagc ttcctgcata gcattgctca tattaaagtt gacgcgcaac tgacccgggc
     4081 caattttccg cacgcctgac tcatcatcgc ttaaaagcaa gcccgaggca gtaagattag
     4141 acggattatc cgttaaaaag agatcatatt cttgacttat ctgcctttca tccggcgtga
     4201 tgcaggtggc gccccagttt tctaactgac gcagcacaat cgcgcgaacc tcgttggacg
     4261 tcacatcgac catcacgctc acgtcgtcca gcaggcgctc ttcgacctga gtatgctgat
     4321 cgtgaggaag cattttgaca tgaacggtat agcgcgtgcc cagcgtttct cgcgctttaa
     4381 tgttgagatg accgcccagt ttgcgcgcca gttgattgca cagccagaag gtgagcggat
     4441 tcgctttgcc gtaacggtcg ccctgcgttt cattcatata cgggaaatgc agattatcaa
     4501 tctcgtttaa cgttacgcct tcgcccgtat ccagaatacg gaaagtcaga cgctccgcga
     4561 tagattcatc ctgctcgact tcaagcgtaa ttttacccat agcggtcgtc gtgacggcat
     4621 actgaatcaa cagcagcaaa atccggcgca gggcgtcgcg atcgccccag cgttcatcgt
     4681 tgccgctaag atggttatta atcagcagtt gcagcccttt acgcttaatg gcgggcagca
     4741 cttccggcac gacttcgtca ataagatcct gcagggagaa cagcgtggct tcgcttttcc
     4801 atgcgtcatt ttccagcata ttcgccagtt ggatttcatc gatcatacgt actaatacat
     4861 ccgcctgatc cgccagtttc aggctttccg gcgtggtgac tgccgcggcg ttaaccgcca
     4921 gttggcgtac gggctcttta agcgtgttgc tgatattttg cataaaggcg gcgcggccct
     4981 gctgattctt ctcatacaaa cgctgcgcct gtttaagctt cttattcacc agcacttccc
     5041 ggtcctgatc gcgaataata aagatctgcg tgcggggggc gatctggctg cgaaacagac
     5101 ggatctcata cagttcgtta ttaattgtcg cctgaatcac gccctgatgc tgctccgcca
     5161 tgctggtaat attttgcagg ttaagatgcg gcaacagatg atcggcgatt ttattgctga
     5221 tcacggtgcg gttgccttcc tgatcgtaga ccagcagacc cagcggcagc agagaaacga
     5281 tctcttcatt aatggcgcgt aagacgcgaa gctcattatt cgccgcgttg ccggatgtcg
     5341 attccgtcga ccgtcccggc tgatgacgga acgtggcgta gccaaataac gccaacgcca
     5401 gcagcccgat gttcagcagt aaaggcagca aaatattttg caacgtatca agcaaaagcg
     5461 taccgaacgg tacctgccag atcaggcgca ttccggtaga gttaagcgct gaggagatct
     5521 caatttttga accgttaaag ctaatcgtga cgctatctgg cgcttccttt tcactgcttc
     5581 gccccgtcgt ctgggttgcg tcaggctcta tccgaaaact gtccagcggc attcccggcg
     5641 ggattaaatc attaatgggc agatcaaacg ccaccacggt tgccagatgt cctggctgat
     5701 tgaaggtcgt gcgcagcgta aaatagtgac cgttttgcca ggccagtttt cgcaatgagg
     5761 agaaactttc gcgctcatcc agcgcattcg cctgctgcaa catctctgcc cggcgggaat
     5821 cgacgatatt gccaatagtg gactctttaa agccggaaga gagatctttc aacggtaggg
     5881 tagagataag aatcaggctg ttatcctgtc cgttgaggta atacattgac cacggcacgt
     5941 tttccgcgcc ccacagcgta tccagataag ttgacatacg ctgcgtcatt tccagcgtgg
     6001 cgctgtcatg ggaaccgaaa atcagcgctt cagttttacg tcgcggcttt tcaagataat
     6061 acacatcctg tttcagacgc gtttcctgaa gtccttcacc tgtcgatggc gtagtggtcg
     6121 cggcgatgtt gtcataaatt tgccaggtaa cataccgcca ggtgtccacg cgtttatgaa
     6181 tagcgtgagt gatatcgaca atttgatagc ttttgtcttt caaccaggcg ttgacggcgc
     6241 tctgtaccat aacgcccatc gttaccagca gcacaatgat cagcaataag aagaaacggg
     6301 taatgcttcc cggtagaagg gagaatcggg tagagaccgt tgtgtcagac tgactcattt
     6361 atgtttacga cctgtaaaag caacgctgaa ggtgaagggc agtataaagg gtaatgaatg
     6421 aatttccaga ctcttacgtc atgccgggca acttaacacg cgctccgtcg gcgggacggg
//
LOCUS       DAJVBX010000225         6404 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.225, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000225 DAJVBX010000000
VERSION     DAJVBX010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 6404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6404
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.225"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(494..892)
                     /gene="vapC"
                     /locus_tag="OPV72_003989"
     CDS             complement(494..892)
                     /gene="vapC"
                     /locus_tag="OPV72_003989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA(fMet)-specific endonuclease VapC"
                     /protein_id="HCR9916159.1"
                     /translation="MLKFMLDTNTCIFTIKNKPEHIRERFNLNTSRMCISSITLMELI
                     YGAEKSLAPERNFAVVEGFISRLEVLDYDTQAAIHTGQIRTELARKGTPVGSYDQMIA
                     GHARSRGLVVVTNNLREFERIPGIRIEDWC"
     gene            complement(892..1119)
                     /gene="vapB"
                     /locus_tag="OPV72_003990"
     CDS             complement(892..1119)
                     /gene="vapB"
                     /locus_tag="OPV72_003990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin-antitoxin system antitoxin VapB"
                     /protein_id="HCR9916160.1"
                     /translation="MHTTLFFSNRTQAVRLPKSISFPEDVKHVEIIAVGRSRIITPVG
                     ESWDSWFDGEGASTDFMSTREQPAVQEREGF"
     gene            1296..1547
                     /locus_tag="OPV72_003991"
     CDS             1296..1547
                     /locus_tag="OPV72_003991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_449411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916161.1"
                     /translation="MHKKHMCPWLLPGLLGLARCAPVPHTYAAIIEAGFYPEGTDLQL
                     VLKIIETARQEIRLMDYSFTSWEVVRFEHSVSTKFSMSK"
     gene            1822..2628
                     /locus_tag="OPV72_003992"
     CDS             1822..2628
                     /locus_tag="OPV72_003992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1460 domain-containing protein"
                     /protein_id="HCR9916162.1"
                     /translation="MIMKVNAWTILLMSAHLTACAVPGTEKYQTSMDSVTAEKISRII
                     QSDVIPYKGENHGEVISRVSSAFLGTPYQADTLIGGPGIPEVLVANFNGVDCFTLADY
                     VEALARSDNQKSFLHNLARTRYAAGKVAYLSRRHFFSDWFAAAPRNARDVTPDISPDY
                     VVVDKQLNHKPDGGEYIPGLGIHPRKINYIPGRAINQQVMNHLKNGDYIGVYSPLDGL
                     DVSHVGIVVRHDEQVWFRNASSLAANRKVVDTPFMEYMHSRLGIVVLRAE"
     gene            complement(3261..4382)
                     /locus_tag="OPV72_003993"
     CDS             complement(3261..4382)
                     /locus_tag="OPV72_003993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916163.1"
                     /translation="MSITNQINKASSLASLRQPQRDKDGQIIKGSIWGTDISRTDYVQ
                     MTNGQDAQVLNVGFTDRSGRPMAFGNDSHDFVQALEDSLDETFNDGDFRTAVMENVFP
                     CEFRPYGTDPTPIRRQALQNRTVRFKHNGAFNPAKDAPSTTAIKGASVTVTPVLNPET
                     NKTGILCSAATHVSDFDMMGGWTEGALIQTVGDMQVQYSRQMFAAVVDVLKDTPDLQI
                     IEAAPLSGKPSDQAEDLLDTLALNLPVELGNTLSDYAVLVPERLEAILDRAAQRAGHE
                     DISELLGCTVCSYAGDDTGVYLLPKRFASISFRSTKDAKTVDVKVTRNSNTAGYDLEL
                     ISVVDVLATGSVKVKAGEFDVEKDASFPLIHVIRFTTPE"
     gene            complement(4484..4894)
                     /locus_tag="OPV72_003994"
     CDS             complement(4484..4894)
                     /locus_tag="OPV72_003994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916164.1"
                     /translation="MSISYRKLDIALSADKETVLVFGQELSTKYFTEIVVTTMLNSTG
                     SDMANSNRILNDIHAAGLDAGDYGKYSRWWAQSNAQERQEAERRRKEAKAHQERMAAI
                     HATPEEIAKAVAERKAREEALIKRFGNKGAAFGL"
     gene            complement(5022..5225)
                     /locus_tag="OPV72_003995"
     CDS             complement(5022..5225)
                     /locus_tag="OPV72_003995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000184035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916165.1"
                     /translation="MTNNTNDTIKIDPRTPEGRKALRLMVVPPKALIATLGLPAKENR
                     PYYSKAALCLMAVDAGLTPRDFM"
     gene            complement(5229..5948)
                     /locus_tag="OPV72_003996"
     CDS             complement(5229..5948)
                     /locus_tag="OPV72_003996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000082599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HCR9916166.1"
                     /translation="MSQQEISIINLDQLVSMTSVEIAELTGKEHRNVLRDIRNMVEEL
                     NALKTEHCSKLSSPIGVIEDVYLNAQGKQQPLYRLDRKHTFILVAGYSVHLRAKCYDH
                     IQTLERRVLQLEDQKKRAAIQSANRRGVTWGDYCKANGLPAQKLMTILKKERKLFRVH
                     SSSGEWSVNPNYVEYFRIIKPTDHRFNPNGINIRFNAKGLEFFSRPENVLKMHRKVIA
                     VHGSDAAKQQHIQAVAKLEGR"
BASE COUNT         1653 a         1520 c         1556 g         1675 t
ORIGIN      
        1 ggtgagcgac aaatctgccg ggagcagatt tgaacgtcgc gtgcgacggc ccgtcagggc
       61 gaggcccatg gatgggccga gtaatccgta gccaacacat aaacaacttg aagtatgaag
      121 ggtatataac gggaaagaag ccatatcggc ctggtaaatc aacgtctgtg atttaagttg
      181 caggaaacgg ctatggagag gggatgcggc agttatcggg cagtaacggc attgttcagt
      241 gagtatccag gaaacaaaaa aagaagggag cggtactccc ttcgtaacca tgtcagaata
      301 cgacattttg gtactctttt atttattatc tggccgtaaa agttatgctg ttggcagata
      361 tctccagtca acataaaaaa ataccaccag ctaaaaatgt gatgcaaacc accattaagc
      421 aggtaaccaa attgactgtg ccactacaat ccggaaaaga gtttgaatcc ggggataaca
      481 tctgatgcag aaattagcac cagtcttcga ttcggatacc cggaatgcgt tcaaactcgc
      541 ggagattgtt tgtgacgacg accagtccgc ggctacgggc atggccagca atcatctggt
      601 cataagaccc gacaggtgtt cccttgcggg ccagttcggt acggatttga ccggtatgta
      661 tcgctgcctg tgtatcgtaa tccagaacct caaggcggga gataaatccc tccacgactg
      721 caaaattacg ctccggtgcc aggctttttt cagcaccgta aatcagctcc attaaggtga
      781 tggagctgat acacattcgg gatgtattga ggttgaagcg ttctctgatg tgttcgggct
      841 tatttttgat ggtgaaaata caagtattgg tatcaagcat gaatttcagc atcagaatcc
      901 ttcccgttcc tgtactgcgg gttgttctct ggtgctcata aaatcagtac tggcgccttc
      961 gccatcgaac cagctgtccc aggattctcc gactggagta atgattctgc ttctaccaac
     1021 cgcaatgatt tcgacatgtt tcacatcctc cggaaaggat atcgatttag gcaatctgac
     1081 tgcctgggtc cggttactaa aaaaaagtgt tgtgtgcata actgccccct ttctggatat
     1141 acaacgcgta tatccattat gagtagaggc gatgtatatg tcaaagagat atacaggaaa
     1201 aaataatcca gtcacatgac gcgcactccg cagggcatcc ttgtccgact ccggcatttc
     1261 tgaatacatc caatgaagga aataccatgc aaacaatgca taaaaaacat atgtgcccat
     1321 ggcttctgcc cggtttgctc ggtctggctc ggtgtgcgcc agtaccgcat acttacgcag
     1381 ccatcattga ggcaggattt tatccggaag gtacagatct ccagcttgtt cttaagataa
     1441 ttgagaccgc gcgacaggaa atccgtctga tggactattc cttcacctct tgggaggtgg
     1501 tccggttcga acattcagtg agtacaaaat tctccatgtc aaagtgatcg tcagcgacga
     1561 ccgccacacc gaggtggacg cgtcagaatc gctgatcgga cacgtcgcaa tctacactct
     1621 gacttataag ccagcctgaa ggggcatgtt ggctttgacg atcaggcaaa aaacaacggc
     1681 gaataaagtc gtatgatgat cttcacattt atcatcatca gcgttcatat tactcaacct
     1741 gtaatcaacc tctggcgttt ttctgtatcc atcacaacca tttccggtaa aggtaaaaaa
     1801 gggatttgaa cctttccgga gatgataatg aaggtaaatg catggacaat tttgcttatg
     1861 tcggcgcatc tgacggcctg tgccgtccct ggcacagaaa aatatcagac cagcatggac
     1921 agcgttacgg cagaaaaaat aagccggatt atccagtcgg atgtcattcc ttataaaggc
     1981 gaaaaccatg gagaagttat cagccgcgta tcgtctgctt ttctcggaac accttatcag
     2041 gcggatacgc tcatcggtgg gcccggcatc cccgaagtcc ttgtagcgaa tttcaacggc
     2101 gtggactgct ttaccctggc tgattacgtt gaagccctgg cccgcagcga taatcagaaa
     2161 tcgtttctgc ataatcttgc caggactcgc tacgccgcgg gcaaagttgc ttatctcagc
     2221 cgccggcact tcttctctga ctggttcgcc gcagcaccgc gtaatgcacg ggatgtaacg
     2281 ccggatatca gccctgatta tgtcgttgtt gacaagcagc ttaaccataa acctgatggc
     2341 ggcgagtaca ttcctggtct gggcatccat cctcgtaaaa taaattacat tcccggaaga
     2401 gccatcaacc agcaggtcat gaaccaccta aaaaacgggg attatatcgg tgtctactcc
     2461 ccgcttgacg ggctggacgt ttcacatgtg ggtatcgtag ttcgccatga tgaacaggtg
     2521 tggttcagga acgcctcctc attggccgca aacagaaaag tggtggacac accgtttatg
     2581 gaatacatgc attccagact gggcatcgtt gtgctgcggg ctgaatgata aagtcattac
     2641 cggagtcgcc agctgataat agccgtccga cataggtatt gaaaccctgt gtactgtggg
     2701 gccgacacgg aaaattgctg taaattcgtg gatttagtaa atactagaag atatttgtct
     2761 ggagcgggcg aagggaatcg aggtatcgaa gataatcagc cgctaaccat ttgcttccta
     2821 aaggatgatg aatccttgtg gttacagtta tggttacaca ttaatttatc tctggtcaag
     2881 tcctctcgtg actctggtca agtcctctcg tgactctgga acgagtaacc gaagtcctaa
     2941 ctttaagaca gtggccccaa tcgtccagac ttgaaagggg ccaagggggg agaggcaccg
     3001 acctttgtct attagatacc tacagagatt tttgtgagat tttttaatac aaggtcataa
     3061 cctaccgcca ccagccccca ccgaccgcaa agtgaagacc tgtaagcacc agagcaatag
     3121 ctattgcggg catactgctg attgttatta tctatcactc cctgtagagc atctggcaga
     3181 ccaagtggac acagaggacg agctcaaaca actcctgtaa gctcatggat gtactcctta
     3241 tgttcactca gggtttatag ttactctggg gtagtaaacc gaataacatg tatcaacggg
     3301 aaagaggcgt ctttctcaac gtcaaactca cctgctttca ccttaacgga accagtagcc
     3361 aacacatcga ccacactgat taactcaagg tcatacccag cagtgttact atttcgggtc
     3421 actttgacat ctaccgtctt agcgtcttta gttgacctga aagagataga agcgaaccgc
     3481 ttaggcagga gatagacacc tgtatcatcg cccgcatagc tgcatacagt gcagcccaat
     3541 agctcactaa tatcctcatg acctgcgcgt tgagcggctc ggtccaagat tgcctcaagt
     3601 ctctcaggga ccaatacagc gtaatcgctc agtgtatttc ccaactcgac cggaagattc
     3661 aacgctaatg tatccagaag atcttcagct tgatcagacg gtttaccact tagtggggct
     3721 gcctcaatga tttgaaggtc tggcgtatct ttcaggacat cgaccacagc ggcgaacatc
     3781 tggcggctgt attgaacctg catatcacct acagtctgga ttaatgcccc ctcggtccaa
     3841 ccgcccatca tatcgaagtc agatacatga gtagcagcag aacacaggat gcccgtctta
     3901 ttggtctcag ggttcaacac tggggtgaca gttacgcttg cccctttgat ggctgtggta
     3961 gacggagcat ccttagctgg attaaacgcg ccattatgct taaagcggac ggtgcgattc
     4021 tggagagcct gacggcgaat aggcgtaggg tcagtgccgt atgggcgaaa ctcacaaggg
     4081 aagacattct ccattacagc agtgcggaag tctccatcat tgaaggtctc atccaaagag
     4141 tcctccagcg cctgaacaaa atcatgtgaa tcattcccga aggccatcgg acggcctgag
     4201 cggtccgtaa agcctacgtt gagaacttgg gcgtcttgac cattggtcat ctgaacatag
     4261 tcagtgcgtg agatgtcagt gccccatata gaccccttaa tgatttgacc gtctttatct
     4321 cgctgaggct gacgcagaga agccagtgag gatgctttgt taatttgatt tgtaatagac
     4381 acgatgaata tctccttatt gtatgaatgc actacgtaaa aagtaactgg tgacaccatt
     4441 ggtcttatct cagaatccaa gcagcgccac cgaaagttat cagttacagc ccgaaagcgg
     4501 cccctttatt gccgaagcgt ttaatcaatg cttcctctcg ggctttacgt tcagcgaccg
     4561 ccttagcaat ctcttctggt gtcgcatgaa tagcagccat acgttcttga tgtgccttag
     4621 cttctttacg tcggcgttca gcctcttggc gctcctgtgc gttgctttga gcccaccagc
     4681 gggaatactt gccgtaatca cctgcatcaa gaccagcggc gtgaatatcg ttaagaatac
     4741 gatttgagtt cgccatgtca gagcctgtac tgttcagcat ggttgtaacg acaatttcgg
     4801 tgaaatactt agtggatagc tcctgaccga ataccagtac agtttctttg tcagcgctca
     4861 gtgcgatatc cagtttgcga taagaaatag acatgtttgt ttctcctttg aaaagatgtt
     4921 ttaaaaggat taaactcatc ggtcttccat aggtattcct acggcgtctc cccgtatctt
     4981 ggtcagttca aaaggtggtg ctagctgtgc tagtgggtta attacatgaa atctcttggg
     5041 gtcagccctg cgtcaaccgc catgagacag agggcagctt tagagtaata cgggcggttt
     5101 tccttggcag gcagacccag agtagctatc agtgccttgg ggggtaccac catcaggcgt
     5161 aacgccttac ggccttctgg tgtccttggg tcaatcttga ttgtgtcatt tgtgttatta
     5221 gtcatgaatt acctcccctc cagctttgct actgcctgta tgtgttgctg tttagcagcg
     5281 tcgcttccat gaaccgctat gacctttctg tgcatcttga gtacgttttc aggtcggctg
     5341 aagaactcca gccccttagc gttaaaccga atgtttatac cgtttgggtt gaatcgatgg
     5401 tcagtaggtt tgataattcg aaagtactcc acatagtttg gattgactga ccactcgcca
     5461 ctgcttgaat gtactcggaa cagcttgcgc tctttcttaa ggatggtcat cagtttctga
     5521 gcgggtagac cattggcctt gcagtaatcg ccccaagtca cgcctcgacg attagctgac
     5581 tgaatggctg ctcgtttctt ctggtcttcc agttgaagaa ctcgacgttc taacgtctga
     5641 atatggtcgt aacacttggc gcgtaggtga acagaatagc cagcgaccag aataaaagta
     5701 tgcttacggt cgagacggta cagaggctgc tgtttcccct gcgcatttag atagacatct
     5761 tcaatcaccc ctataggact gctcagtttt gagcagtgct cagttttgag tgcgttaagc
     5821 tcctcaacca tattgcgaat atcacgaagg acatttcggt gctccttgcc tgtcagctca
     5881 gcaatttcaa ctgaggtcat ggacacaagc tggtcgaggt taatgatgct gatttcttgt
     5941 tgagacatag cttgatttcc tttttgtttg caccctgaag tcgcaccccc actgacctac
     6001 tcaaagtccc caagcgaagg gagaccagca ggacaacagg atgcaaacag aatgactttg
     6061 agattgaatg aatgaatgac gatgattgtg tcgtagctgt gcggagctac tgtatggtga
     6121 agcgcgagag gtggaacttt gagagacacg tggtgagtgg ttcggagtgt gtctcctatt
     6181 agtaagtcgt attgattcgt attgattcgt attgatttac tactgggagg gtctctcaag
     6241 ggtctctgag ccacgctagg catcaggcca tacgaaacta catggcatcc taaagaatgg
     6301 agtacaggac catacagggc catacagtta gcttctgggg taatgccttg aggagaccta
     6361 taggtttggt gattgattgt tataaatatc atcacctctt aagg
//
LOCUS       DAJVBX010000226         6390 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.226, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000226 DAJVBX010000000
VERSION     DAJVBX010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 6390)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6390
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.226"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            90..2279
                     /locus_tag="OPV72_003997"
     CDS             90..2279
                     /locus_tag="OPV72_003997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system tip protein VgrG"
                     /protein_id="HCR9916167.1"
                     /translation="MSFVSTNNKSGMGGLTTTTPPITGESGGVTADSVAGSVADAAEA
                     AVEQAAGSLFGALPEPSGLVKAAVAAAQAAAAAGMAQDAVSAIVSAVAGGPGAHNVTV
                     SGSAVPPGALLFASLDGGETLSELFSYVVQLKTPDTLNLGYVSPAANLPLKPMVGKDL
                     CVNIELDGGGKRHISGLVTAARVVGHEGRSVTYELRMEPWVKLLTHTSDYKAFQNKTV
                     VDILDEVLAEYPYPVEKRLVESYPVRTWQVQYGETDFDFLQRLMQEWGIYWWFEHSED
                     SHTLVLADAISAHKACPDSPLVEWHQEGLKLDKEFIHTITANESLRTGQWVLDDFDFT
                     KPRSLLANTVANPRETGHATYEHYEWPGDYFDKSEGEMLTRIRMEAQRSPGSRVLGGG
                     NIRTLMTGYTFTLENYPTAEVNQEYLLMQTLLFVQDNAQHSGQDQHFTFSTRFELHPT
                     REVFRPQRTVSKPHTKGPQSAIVTGPAGQEIWTDQYGRVKVQFGWDRYGKMDENSSCW
                     IRVSYPWAGKGFGMIQIPRIGQEVLVDFKNGDPDLPIIVGRTYNQDTMPPWGLPGMAS
                     QSGIFSHSLYGGPTNGNMLRFDDKTGAEEVKFHAEKDLNTTVKNNETHTVMVDRTKTI
                     IKNETNSIGEDRNTTVTKNDGLSVKLAQTINIGTTYRLDVGDQFTLRCGNAALVLHKD
                     GSIEFCGKQLMLHTSDVMQLIGKGIDMNPDGGTAVTADDIAPLPTSE"
     gene            2303..2749
                     /locus_tag="OPV72_003998"
     CDS             2303..2749
                     /locus_tag="OPV72_003998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DcrB-related protein"
                     /protein_id="HCR9916168.1"
                     /translation="MDRPYRIQEGCFVLPETFTDRSVNIFILEGNERTSPSLNISRDT
                     LKPDEDLPAYIDRQIALMKKNLGQHRVLSRAPAQAGTGNDALMGEQIAATHKSGKTEV
                     YQRQAGFIATPGKVLVFTLTSPRPFDDKADLLWNTWLAGFQPDKNE"
     gene            2768..>6390
                     /locus_tag="OPV72_003999"
     CDS             2768..>6390
                     /locus_tag="OPV72_003999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAAR domain-containing protein"
                     /protein_id="HCR9916169.1"
                     /translation="MYEAARVDDPIYHTSALAGFLIGAIIGIAIIALAAFAFFSCGFL
                     AGLILGFMADQIASGVLQLGEAIGRSIHHTAGKILTGSENVSTNSRPAARAVLSTVKC
                     DNHIAEKRIAQGSGNIYINSQPAARKDDHTECDAVVEDGSPNVFLGGGTQTVLEISSE
                     IPDWLRKVVDVLFVVASLLGGLAGAWRQAAKLGTKFGTKCAAKFIGGELTGMAVSEAI
                     SGLFSNPVDVTTGQKILLPETDFTLPGRLPVTCSRFYASHLETVGLLGQGWRLNWETS
                     LREDDEHITLTGVQGRELRYPKMMLTPGHQIFGPKEQLYLSRLHDGRYVLHYTDRSYY
                     VFGDFDSDGMAYLLFMETPHRQRIVFGHEGGRLVRIASSSGHHLLLHRTQTPAGERLS
                     RIELVQGGTCGNLVEYRYDDNGQLTGVVNRAGTQVRQFAYENGLMTAHSNAAGFTCRY
                     RWQELDGAPRVTEHDTSDGEHYRFDYDFAAGTTTVTGRQGESWQWWYDRETYITAHRT
                     PGGGMYRFTYNEDHFPVNIGLPGGRTVAYEYDIQNRVVKTTDPEGRVTQTQWNGEFDE
                     ITRTALDDDAVWKTQYNAHGQPVQETDPEGRVTQYAYDEQGQMCSRTDAAGGTVVTAF
                     DSRGQMTRYTDCSGRSTGYDHDEDGNLTRVTDAEGKVVRISYNRLGLPETVNSPGKQQ
                     DRYTWNALGLMSSHRRITGSVESWRYTPRGLLAAHTDEEKRETRWQYTPEGRVTALTN
                     GNGAQYRFSHDADGRLMREVRPDGLSRTFILDDSGYLTAIQTTGTQGGVRRETQQRDA
                     LGRLLRTENEHGQRTFSYNRLDQITAVTLTPTEAGQQQHRMQADTVRFEYDRSGWLTA
                     EHAGNGSICYQRDALGNPTDITLPDGQHLTHLYYGSGHLLQTALDGLTVSEYERDSLH
                     RQIMRTQGQLATYSGYDDDGLLSWQRSLAPGSAPVLPGQRPARQGCVTSRDYYWNNHG
                     EVGTIDDGLRGSVVYSYDRSGYLTGRSGQMYDHDRYYYDKAGNLLDNEGQGPVMNNRL
                     PGCGRDRYGYNEWGELTTRRDQQLEWNAQGQLTRVISGNTETHYGYDALGRRIRKATY
                     GRHTGHTARSRTDFVWEGFRLLQENVQQQGWRTYVYDAEQPYTPVASVTGRGESRQVW
                     YYHTDVTGTPQEVTAADGTLVWAGYIRGFGENAADISNSGAYFHQPLRLPGQYFDDET
                     GLH"
BASE COUNT         1447 a         1702 c         2101 g         1140 t
ORIGIN      
        1 taacaggctg gttgcattat aaagtgcggg gcactgtttc ctgacggtga gtctatttat
       61 tttaatccgg tattaaagga gtcactacca tgagttttgt atccacaaat aataaatccg
      121 gtatgggagg gctgacgaca accacgccgc cgataaccgg agaaagtggc ggtgtcaccg
      181 cagattcagt cgccggaagc gtggcagatg cggcagaagc cgccgtggaa caggctgcgg
      241 gatcgctgtt tggcgcattg ccggagccat caggactggt gaaagccgcg gtggcagcgg
      301 cgcaggctgc cgccgctgca ggtatggcgc aggatgcggt atcggccatc gtctctgctg
      361 ttgcaggcgg gccgggggcg cataatgtga cggtcagcgg cagcgccgta ccgccgggcg
      421 cattactgtt cgccagcctg gacggcggcg aaacattaag tgaactgttc agttatgtgg
      481 tacagctaaa aacgcccgac accctgaatc tgggctatgt ctccccggcg gccaacctgc
      541 cgctcaaacc gatggtgggc aaagatctgt gcgtcaacat cgaactggat ggtggcggta
      601 aacgacatat cagcgggctg gtcacggcgg cgcgggtggt gggccatgaa gggcgttcgg
      661 ttacctatga gctgcgtatg gagccgtggg taaaactgct gacccatacc agcgactaca
      721 aagcattcca gaataaaacc gtggtggata ttctggatga ggttctggcg gaatacccct
      781 acccggtgga aaagcggctg gtggaaagct acccggtacg cacctggcag gtgcagtacg
      841 gtgaaactga ttttgatttt cttcagcgac tgatgcagga gtggggcatc tactggtggt
      901 ttgagcacag cgaggacagc cacacgctgg tgctggcgga tgccatcagc gcccacaaag
      961 catgtccgga ctcgccgctg gtcgagtggc accaggaagg gctgaagctg gacaaggagt
     1021 ttatccacac tatcacggca aacgagagtc tgcggactgg ccagtgggtg ctggatgatt
     1081 tcgattttac gaagccacgt tcattgctgg caaacaccgt ggcaaacccg cgtgaaaccg
     1141 gtcatgccac ctacgagcat tatgagtggc cgggagacta cttcgacaag agtgaaggcg
     1201 agatgctgac gcgcattcgt atggaagcgc agcgcagccc cggcagtcgg gtgctggggg
     1261 gagggaatat ccgcacactc atgaccggtt ataccttcac gctggaaaac tatcccaccg
     1321 ccgaagtcaa tcaggaatac ctgctgatgc agaccttgct gtttgtacag gacaacgcgc
     1381 agcacagcgg gcaggaccag cactttacct tttccacccg ttttgaactg cacccgaccc
     1441 gtgaggtgtt ccgcccgcag cggacggtga gcaaacccca caccaaaggg ccgcagagcg
     1501 ccatcgtcac cggcccggcg ggccaggaaa tctggacgga tcagtacggg cgggtaaagg
     1561 tacagtttgg ctgggatcgc tacggcaaaa tggatgaaaa cagctcctgc tggatacgcg
     1621 tcagctaccc atgggcgggc aaaggcttcg ggatgatcca gatcccgcgt atcggccagg
     1681 aagtgctggt ggatttcaaa aacggcgatc cggatctgcc gatcatcgtg gggcgtacct
     1741 acaaccagga caccatgccg ccgtggggac tgccgggaat ggcgtcgcag agcgggatct
     1801 tcagccactc gctgtatggc gggccaacga acggcaacat gctgcgtttt gacgacaaaa
     1861 cgggcgcgga ggaagtgaag ttccacgcgg aaaaagatct caacaccacg gtgaagaata
     1921 atgaaacgca tacggttatg gtggatcgca ctaaaaccat tattaaaaat gaaaccaaca
     1981 gtattggtga agacagaaac accacggtaa cgaagaatga cggcctttcc gtaaaactgg
     2041 cgcagacgat caatatcggc accacttatc gtttagatgt tggcgatcaa ttcacacttc
     2101 gctgcggcaa tgcggcgctt gttttacata aggacggctc cattgagttt tgtggcaagc
     2161 aactgatgtt gcataccagc gatgtcatgc aactgattgg taaaggtatt gatatgaacc
     2221 cggatggcgg cacagccgta accgccgatg atattgcccc ccttcccacc tctgagtgat
     2281 ctgaattaaa cctggagttc tcatggatcg accataccgc atacaggaag ggtgttttgt
     2341 cctgcctgaa acatttacgg atcgcagcgt caatattttt atcctggagg gcaatgaacg
     2401 aacatcgccc agcctgaata tttcccgcga tacgctaaaa cctgatgaag acctgcccgc
     2461 ctatattgac cgccagattg cgctgatgaa aaaaaatctc ggtcagcacc gggtattgtc
     2521 gcgagcgcct gcacaggcag gaacgggcaa tgatgccctg atgggggaac aaattgccgc
     2581 cacccataaa tccgggaaaa cggaagtgta ccagcgtcag gccgggttta ttgcaacccc
     2641 tggcaaggta ctagtcttca ccctgaccag tccccgtcct tttgatgata aagcagacct
     2701 actctggaac acctggctgg caggctttca gccggataaa aacgaataat cacacggagg
     2761 tgtgaccatg tatgaagcag cccgtgtgga tgaccctatc taccacacca gtgcgctcgc
     2821 cgggtttctt atcggcgcta tcatcggcat cgccattatc gcgcttgccg cctttgcctt
     2881 ctttagctgc ggttttcttg ccgggctgat tctgggtttt atggccgatc aaatagcctc
     2941 cggggtattg caactgggcg aggccatcgg gcgctccatc caccacacgg caggaaaaat
     3001 cctcaccggt tcggagaatg tcagcaccaa cagtcgcccg gcggcgcgcg cggtactgag
     3061 tacggtgaaa tgcgataacc atatcgcaga aaaacgcatc gcccagggct ccggcaatat
     3121 ttacatcaac agccagcctg ccgcccgtaa ggatgaccat accgaatgcg atgcggtggt
     3181 tgaagacggt tcgccgaatg tgtttctcgg cggcggcaca cagacggtac tggaaatcag
     3241 ttctgaaatt ccggactggc tgcgcaaggt ggtggatgta ttgtttgtcg tggcgagtct
     3301 gctcggcggg ctggccgggg cgtggcggca ggcggcaaag ctggggacga aatttggcac
     3361 taaatgtgcc gctaagttta tcggcgggga gcttaccggg atggccgtga gtgaggctat
     3421 cagcgggctg ttcagcaatc cggtggatgt gaccaccggg cagaaaatcc tgctgccgga
     3481 aacggacttc accctgcccg gtcgcctgcc ggtcacctgc tcgcgttttt acgccagcca
     3541 cctggaaacc gtgggactgt tgggacaggg ctggcggctg aactgggaaa ccagcctgcg
     3601 cgaggacgat gaacacatca cgctgaccgg cgtacagggg cgggaactgc gttacccgaa
     3661 aatgatgctg acgcccggcc accagatatt tggcccgaaa gaacagttat acctcagccg
     3721 cctgcatgac gggcgttacg tgctgcatta caccgatcgc agctattacg tatttggtga
     3781 ttttgacagt gacggcatgg catacctgct gtttatggag acgccgcacc gccagcgcat
     3841 tgtcttcggg cacgaaggag gcagactggt acggatagcc tccagcagcg ggcatcacct
     3901 gttactgcac cgcacacaga ccccggcagg ggagcggctg tcgcgaattg aactggtgca
     3961 gggcggcacc tgtggcaatc tggtggagta ccggtatgac gataacggtc aactgaccgg
     4021 cgtggtgaac cgggcgggaa cgcaggtgcg gcagtttgct tatgaaaacg ggctgatgac
     4081 ggcgcacagc aatgcggcgg ggttcacctg ccgctaccgc tggcaggaac tcgacggcgc
     4141 gccgcgcgtg acggagcacg acaccagtga cggtgaacat taccgctttg actatgattt
     4201 tgccgcaggc accaccaccg tcaccggcag gcagggggag tcatggcagt ggtggtacga
     4261 cagggagacg tatatcaccg cgcaccggac gccgggcggt ggaatgtacc gcttcacgta
     4321 caacgaagac cacttccctg tcaacattgg gctgcccggc ggtcgcacgg tggcgtatga
     4381 atatgacatc cagaaccggg tggtgaagac gacagatccg gaaggccggg tgacgcagac
     4441 gcagtggaac ggcgagttcg acgaaatcac gcgcacggcg ctggacgatg acgctgtctg
     4501 gaaaacgcag tacaacgccc acggccagcc agtgcaggag acggacccgg aagggcgggt
     4561 gacgcagtac gcttacgatg aacaggggca gatgtgcagc cggacggatg cggcgggcgg
     4621 cacggtggtg acggcgttcg acagccgggg gcagatgacg cggtacaccg actgttcagg
     4681 gcgtagcaca ggatatgacc acgatgagga cggcaacctg acgcgggtga cggacgcgga
     4741 agggaaggtg gtacgcatca gctacaaccg acttgggttg ccggagacgg tgaactcacc
     4801 ggggaaacag caggacaggt atacctggaa tgcgctgggg ctgatgagca gccaccggcg
     4861 catcacgggg agcgtggaga gctggcggta tacgccgcgc ggtctgctgg cggcgcacac
     4921 ggatgaggag aagcgcgaga cgcgctggca gtacacgccg gaaggccggg tgaccgcgct
     4981 gaccaacggc aacggggcgc agtaccggtt cagtcacgat gcggacggca ggctgatgcg
     5041 tgaggtgcgc ccggacggac tgagccgtac ttttatcctg gacgacagcg gttatctgac
     5101 ggcgatacag accacgggta cgcagggcgg cgtgcggcgg gagacgcagc agcgggatgc
     5161 gctgggccgt ctgttacgga cggagaatga acacggccag cggacgttca gctacaaccg
     5221 gctggaccag ataacggcag tgacgctcac gcccacggag gcggggcaac agcagcaccg
     5281 gatgcaggcc gacacggtgc gttttgagta tgaccgcagc ggctggctga cggcggagca
     5341 cgcggggaac ggtagcatat gttatcagcg cgacgcgctg ggcaacccga cggacatcac
     5401 gctgccggac gggcagcacc tgacgcatct gtattacggg agcgggcatc tgttacagac
     5461 ggcgctggac ggcctgacgg tgagcgagta tgagcgcgac agcctgcacc gtcagataat
     5521 gcgcacgcag gggcagcttg cgacgtacag cggctatgac gacgacgggc tgctgagctg
     5581 gcagcgcagc ctggcgcccg gcagtgcccc tgttcttccc ggccagcgcc cggcgcggca
     5641 gggctgcgtg acgtcgaggg actattactg gaacaaccac ggcgaggtgg gcacgattga
     5701 cgacggcctg cgtggcagcg tggtgtacag ctatgacaga agcggttacc tgaccgggcg
     5761 ctcaggtcag atgtatgacc atgaccgtta ttattacgat aaggcgggca acctgctgga
     5821 taacgaaggg cagggtccgg tgatgaacaa ccggctgccg ggctgtggtc gtgaccgtta
     5881 cggttataac gagtggggcg agctgaccac gcggcgcgac cagcaactgg agtggaacgc
     5941 gcaggggcag ctgacgcggg tcatcagcgg caacacggag acgcactacg gctacgatgc
     6001 gctggggagg cgaatccgca aggcgacgta cgggcggcac acgggccata cggcgcggag
     6061 ccggacggac tttgtgtggg aggggttcag gctgttgcag gagaacgtgc agcagcaggg
     6121 ctggcggaca tatgtgtacg atgcggaaca gccgtacacg ccggtggcga gcgtgacggg
     6181 gcggggagaa agcaggcagg tgtggtatta ccacacggac gtgacgggca cgccgcagga
     6241 ggtgacggcg gcggacggaa cgctggtgtg ggcggggtat atcagggggt ttggagagaa
     6301 tgcggcggac atcagcaaca gcggggcgta ctttcaccag ccgctgcggc tgccggggca
     6361 gtattttgac gacgagacgg ggctgcatta
//
LOCUS       DAJVBX010000227         6276 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.227, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000227 DAJVBX010000000
VERSION     DAJVBX010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 6276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6276
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.227"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            19..666
                     /gene="zinT"
                     /locus_tag="OPV72_004000"
     CDS             19..666
                     /gene="zinT"
                     /locus_tag="OPV72_004000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460229.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-binding protein ZinT"
                     /protein_id="HCR9916170.1"
                     /translation="MIHLKKLTMLLGMLLVNSPAFAHGHHAHGAPMTEVEQKAAAGVF
                     DDANVRDRALTDWDGMWQSVYPYLVSGELDPVFRQKAKKDPEKTFEDIKAYYRKGYAT
                     NVETIGIENGVIEFHRDNNVASCKYNYAGYKILTYASGKKGVRYLFECKDANSKAPKY
                     VQFSDHIIAPRKSAHFHIFMGNTSQQALLQEMENWPTYYPYQLKANEVVDEMLHH"
     gene            775..1563
                     /gene="aadA"
                     /locus_tag="OPV72_004001"
     CDS             775..1563
                     /gene="aadA"
                     /locus_tag="OPV72_004001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cryptic aminoglycoside nucleotidyltransferase
                     ANT(3'')/ANT(9)"
                     /protein_id="HCR9916171.1"
                     /translation="MTLSIPPSIQCQTEAACRLITRVTGDTLRAIHLYGSAVAGDLKP
                     NSDIDLLVTICQPLTETQRATLMQELLALSSPPGASAEKRALEVTVVLYSQLVPWCFP
                     PSREMQFGEWLREDIYQGIYEPAQQDWDMVLLITQILETSIPLKGERAERLFTPAPAA
                     QLLKALRYPLDLWQSTADVQGDEYHIVLTLARIWYTLSTGRFTSKDAAADWLLPQLPE
                     EYAATLRAAQREYLGLEQQDWHILLPAVVRFVDFAKAYIPTQFT"
     gene            1708..2301
                     /locus_tag="OPV72_004002"
     CDS             1708..2301
                     /locus_tag="OPV72_004002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCR9916172.1"
                     /translation="MTGSASSVLKTDTRLLSENLFLNYGLESLFKDVAIIAGNVNYIV
                     FDIDDYYTVQQYITSTFKTVLIGIVTHNEYNFIDEHHAIYRIKVDASIAEWRELLILA
                     AAGQFFPRSEKVRLTANERNVLAMLVKGMDIRQISCELNVHLKTIYSVRYHVLTKLGC
                     RTVLDYQILSVSKAFTHWLTINNVDNVIFRVNSKVIA"
     gene            2370..3218
                     /locus_tag="OPV72_004003"
     CDS             2370..3218
                     /locus_tag="OPV72_004003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCR9916173.1"
                     /translation="MATFSISAMAAQCGVTTANIRSWERYGLLQPTKDEAGNRFYCIE
                     DAIRIQHIIDALSKGFSLKEIKPALYGEETHCRSGWLFYQEEILAQCRKFEPAKLRKL
                     LWRYGREIPPCIVIESILRPLWLWLSAGDDDARRFEKALLDTAIIEYATFQLSSVRKA
                     PAGTMLIAAFSLNDPIELWLETIKYCSEGMRVEVIPWQAPMPDLLSTSFEHIVLWHDE
                     TLTPAQENLIQALKESGKFSLHVKNGSGLTLLPAVYRQHEMPESMQHVAPQIHANGYE
                     KSGTAR"
     gene            complement(3473..3721)
                     /locus_tag="OPV72_004004"
     CDS             complement(3473..3721)
                     /locus_tag="OPV72_004004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HCR9916174.1"
                     /translation="MTTITLVNEQNSTGNPFSAHMLCEQRAIQEITYELLQSQQHVSN
                     KDIIAKLIEKLETEKDVVQLDIYRNALEAVFFQTPDDI"
     gene            complement(3800..3955)
                     /locus_tag="OPV72_004005"
     CDS             complement(3800..3955)
                     /locus_tag="OPV72_004005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916175.1"
                     /translation="MLIRLNWSEKKEQAVDSAESSPSFKVYKIYNKSHKCDAHHVFMI
                     FYYSFMI"
     gene            4038..4583
                     /locus_tag="OPV72_004006"
     CDS             4038..4583
                     /locus_tag="OPV72_004006"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HCR9916176.1"
                     /translation="MIRHIAIFLCSLLMCSTTFADSVTSVSLGALLTALNERMLLMKD
                     VAAYKMKHHLPIEDFTREQNVFAEAEEEAKNNGLDPHSITPFIRSLMDASKAIQYRYL
                     AQWRTGSEPSFPIQTLSVTRQRIRQLDNQMLIIISQRLMVGAFSHEDMVWLRTHFNAP
                     NLNESDISDVLAALSLVRHAR"
     gene            4779..5417
                     /gene="leuE"
                     /locus_tag="OPV72_004007"
     CDS             4779..5417
                     /gene="leuE"
                     /locus_tag="OPV72_004007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine efflux protein LeuE"
                     /protein_id="HCR9916177.1"
                     /translation="MFAEYGVLNYWTYLVGAIFIVLVPGPNTLFVLKNSVGRGVKGGY
                     LAACGVFIGDAILMFLAYAGVATLIKTTPVLFNIVRYLGAFYLLYLGAKILYATLTSK
                     GRAATETVVPFGAIFKRALILSLTNPKAILFYVSFFVQFIDVTAPHTGVSFFILATTL
                     EIVSFCYLSFLILSGAFVTHYIGTKKKLAKVGNSLIGLLFVGFAARLATLQS"
     gene            5590..5952
                     /locus_tag="OPV72_004008"
     CDS             5590..5952
                     /locus_tag="OPV72_004008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1971 domain-containing protein"
                     /protein_id="HCR9916178.1"
                     /translation="MRQIPQNHIHTRSTPFWNKETAPAGIFERHLDKGTRPGVYPRLS
                     VMQGAVKYLGYADEHCSEPEEIMVINAGEFGVFPPEKWHNIEVMTDDTYFNIDFFVAP
                     EVLMEGATSRKVIHAGRE"
     gene            5955..6137
                     /locus_tag="OPV72_004009"
     CDS             5955..6137
                     /locus_tag="OPV72_004009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1869 domain-containing protein"
                     /protein_id="HCR9916179.1"
                     /translation="MGKATYTVTVTNNSNGVSVDYETEAPMTLLVPEVTAEVVKDLVN
                     TVRSYDTENEHDVCGW"
BASE COUNT         1640 a         1358 c         1516 g         1762 t
ORIGIN      
        1 gatgagggta acgttttggt gattcattta aaaaaactga caatgcttct gggaatgctg
       61 ttggtcaata gtcctgcctt cgcgcatggt catcatgctc atggcgcgcc gatgacggag
      121 gttgagcaaa aagcggcagc gggtgtgttt gatgacgcta atgtacgcga tcgcgcgctc
      181 accgactggg atggtatgtg gcaatccgtc tatccttatc tggtcagcgg cgagctggac
      241 cctgtcttca gacaaaaggc gaagaaagac ccggagaaaa cgtttgagga tattaaagcg
      301 tattatcgca aaggatacgc gacgaatgtt gagactatcg gtattgaaaa tggcgttata
      361 gaattccatc gcgacaataa cgttgcatcc tgtaaataca attatgccgg ctataaaatt
      421 ctgacttacg catcgggtaa aaaaggggtg cgctacctgt tcgaatgtaa agatgcgaat
      481 agcaaagcgc ctaaatatgt tcagtttagc gatcatatca ttgccccgcg caaatcggcg
      541 cacttccata tctttatggg aaatacctcg caacaggcat tgttgcaaga gatggaaaac
      601 tggcctacct attatcctta tcagttaaag gcgaatgagg tcgttgacga aatgctacat
      661 cattaagtct gattgcaatg ttaaaagctc gctatgaata gcgagctttt tttctgccgt
      721 tatgccatat ttctggcaat caatataaaa aatacctgcg cccccggagc aacgatgacg
      781 ctgtccatac cgccctcgat tcaatgccaa acggaagcgg cgtgtcgcct gattactcgt
      841 gtcacaggcg atacgttgcg tgctattcat ttatatggtt ccgctgtcgc gggcgatctg
      901 aagccaaaca gcgacattga tctgctggtg acaatatgcc agccgctgac ggagacccaa
      961 cgcgcaacgc tgatgcagga attgctggcg ctttcatcgc cgccgggggc gtcagcagaa
     1021 aaacgcgctc tggaggtcac tgtcgtgctt tattcgcagc tggttccctg gtgttttcca
     1081 ccttcccggg aaatgcaatt tggcgagtgg ctaagagagg acatttatca ggggatttat
     1141 gaaccagcgc agcaggactg ggacatggtg ttactgataa cccaaattct ggaaaccagt
     1201 ataccgctaa agggagaacg cgcggaacgg ctgttcacgc cagcccctgc ggcgcagttg
     1261 ctgaaggcct tgcgttatcc cctcgacctt tggcaatcca cggcagatgt gcagggagat
     1321 gagtatcata tcgttttaac cctggcgcgt atctggtaca ccctttctac cgggagattt
     1381 acctctaagg atgcggcggc tgactggctg ttacctcagt tgccagaaga gtatgctgct
     1441 acgttgcgtg cggcgcagcg tgaatattta ggtctggagc aacaggactg gcatattttg
     1501 ctgcctgcgg tcgtacgctt tgtggatttt gcgaaagcgt acatccccac gcagttcaca
     1561 taagatgccc caggacgtct gtcaggttgc gcaaacggcg ttcctcaact actacttaat
     1621 aggttctcat cgctgaagta agcagatgat cttatgcggg ccatcgaatg gatattccca
     1681 catggctctc gttttgttga ggtggatatg actggttccg catcatctgt tttaaagaca
     1741 gatacaagac tattgagcga aaacctgttt cttaattatg gtctggagtc cttatttaag
     1801 gacgtcgcaa taatagctgg caacgtaaat tatattgttt ttgatatcga cgattactac
     1861 accgtacagc agtatattac ttccacattt aaaacggtac tcattgggat tgttacccat
     1921 aatgaatata actttattga tgaacatcat gctatatatc gaataaaggt cgatgcctct
     1981 attgctgagt ggcgcgaatt actgattttg gccgctgctg gtcaattttt tcccagatca
     2041 gagaaagtca gattaacggc gaatgaaaga aatgttttgg cgatgcttgt taaaggaatg
     2101 gatatccgac aaataagctg tgagctgaat gtacatttaa aaactattta ctcagtacgc
     2161 taccatgtcc tgactaaatt aggttgtaga acagttctgg attatcaaat actgtccgtc
     2221 tctaaagcct ttacgcactg gcttacaata aataatgtcg ataatgtaat tttccgtgta
     2281 aatagcaagg tcattgctta ataatgattt gcttctgatg gcgtttaggt tcactatgct
     2341 ttcttacatc atcatgaggc cagacaggca tggctacttt tagtattagc gcaatggcgg
     2401 cgcagtgtgg tgtcacaaca gcaaatatca ggtcctggga acgctatggc ctgcttcaac
     2461 ctaccaaaga tgaagctggc aatcgttttt attgcataga agatgctatc agaatacagc
     2521 atattatcga cgcgttaagc aaaggcttct cattaaaaga gattaaacct gccctctatg
     2581 gtgaagaaac gcattgccgc tcgggatggt tattctacca ggaagagatt ttagcgcagt
     2641 gtagaaaatt cgaacccgcc aaattgcgaa aattactctg gcgttatggt cgggaaattc
     2701 cgccgtgtat cgtaattgag tcaatactgc gtcctttatg gctgtggttg tccgcaggcg
     2761 atgatgatgc acgccgattt gaaaaggcat tactggatac tgcgattatt gaatacgcca
     2821 cgttccagct aagtagcgta cgaaaggcgc cagcaggcac aatgcttatt gctgcgtttt
     2881 cgctgaacga ccccattgag ctatggctgg aaacgattaa atattgtagt gaaggtatgc
     2941 gagttgaagt catcccctgg caggcgccga tgcccgatct tttatcaacg tctttcgagc
     3001 atattgtttt gtggcatgat gagacattaa ctcccgccca ggaaaatctt attcaggctt
     3061 taaaagaatc gggtaaattt agtcttcatg tgaaaaatgg ctcaggctta acattactgc
     3121 cagccgtata ccggcagcat gagatgcccg aaagcatgca gcatgttgca ccgcaaatcc
     3181 atgcaaacgg ctacgaaaaa tcaggcaccg cacgttgagg catctgcatt attaacgaac
     3241 aggggaggag taaccccctc ccttgtttat acccttcata cttcaagttg cttatgtgtt
     3301 ggctacggat tactcggccc atccataggc ctcgccctga cgggccgtcg caagcgacgt
     3361 tcaaatctgc tcccggcaga tttgtcgttc accccagtca catagttatc tatgctcctg
     3421 gggactcact cccttgccgc cttttagcaa cacgaattat tttgggtata tattagatgt
     3481 cgtcaggtgt ctgaaaaaaa acggcttcta aggcattgcg gtaaatatca agctgcacta
     3541 cgtctttttc tgtttccagt ttttcaataa gtttggcgat gatatcctta tttgagacat
     3601 gctgctgcga ttgcaatagt tcgtaagtaa tttcctgaat agctcgctgt tcacataaca
     3661 tatgtgcaga aaaaggattg ccagtactat tttgttcgtt gactagtgta atggtagtca
     3721 tatttcacca tattcgatgt aaattgaagc cgatctccct gagcggggga gagaaattag
     3781 tgacctatta aagttagacc tatatcataa aactgtaata aaaaatcata aaaacgtgat
     3841 gtgcatcaca tttgtgtgat ttgttgtata ttttatacac tttaaatgaa ggtgaagatt
     3901 ccgcagaatc aacggcctgt tcttttttct cactccagtt taaacgaata agcattaata
     3961 cccatctgta ataattactt aatgttatct taataaaggt aaattactgt cagacctccg
     4021 taaaaggagg ttgattaatg attcgtcata tcgccatttt tctttgttct ttattgatgt
     4081 gcagcaccac ttttgccgat tcggtaacgt cggtatcgct tggcgcgctc ttaaccgcgc
     4141 tcaatgaacg catgttatta atgaaagatg tggctgctta taaaatgaag caccatctgc
     4201 cgatagagga tttcacacgt gaacaaaatg tttttgccga ggctgaagaa gaagcgaaaa
     4261 ataacggtct ggacccgcat tcgataaccc cttttattcg ttcgctaatg gatgccagta
     4321 aagcgataca gtaccgctat ttagcgcagt ggcgaaccgg ctcagaaccc tcctttccga
     4381 tacaaacctt gtcggtcacc cggcaacgta ttcgacaact tgataatcaa atgttgatca
     4441 ttatcagcca gcgcctgatg gtcggcgctt tcagccatga ggatatggtg tggctgagaa
     4501 cgcactttaa tgcgccgaat ctgaatgaga gcgatatcag tgatgtgttg gcagccctat
     4561 ctttggtgcg acacgcgcgt taatccccca tgaggaaacg tgggccaata cctggtgatt
     4621 gcctgcgggg gcgcgataaa agaacgtttt tgggtgatgg ggatataagc gtggcggaat
     4681 agcggctgga gagacgtggt ttcgcttccc atcttccgat gcattcgtta gcatactgtt
     4741 tcgcagctaa gcgtaaatgt tttcaggaag aggttaatgt gttcgcggag tatggtgttc
     4801 tgaattattg gacgtacctg gtcggggcga tttttatcgt tctggtacca gggccgaata
     4861 cgctttttgt gcttaaaaat agcgtgggac gcggggttaa aggaggatat cttgccgcat
     4921 gtggcgtgtt tatcggtgat gcgatattaa tgtttctggc gtatgcgggc gtggcgacgc
     4981 tgatcaaaac aacgccggtt ctgtttaaca ttgttcgcta tctcggcgcg ttttatctgc
     5041 tctaccttgg cgcaaaaatc ctttacgcca ctctgacctc aaaagggcgt gcggcgacgg
     5101 aaacggtagt tccttttggc gctattttta agcgtgcttt aattcttagc ctgacgaatc
     5161 ctaaagccat acttttttat gtttcctttt ttgtgcaatt tattgatgtt actgcgccgc
     5221 atactggggt gtcatttttt attttggcca ccacccttga aatcgtcagt ttttgctatc
     5281 tgagcttttt aattctttct ggcgcttttg taacccacta tattggtacc aaaaagaaac
     5341 tggcaaaagt gggcaattcg ttgattggcc ttcttttcgt cggatttgcc gcccggctgg
     5401 caacgctcca gtcttaaccc cctggacccg tcgtgaacgg cgggtcattg ctctcctttc
     5461 ggttttattg cgtggaaaac agcaaaatag taaccaataa atggtattta aaatgctgtt
     5521 tttggagcgt aaccttttta cgacagcgat gagattatcg ctgagtaacc tgcgggaaga
     5581 gggaagcaaa tgcggcaaat tccacaaaat catatccata cacgttccac gcccttctgg
     5641 aacaaagaga cggcgcctgc cggaattttc gaacgccacc ttgataaggg aacgcgaccc
     5701 ggcgtttatc ctcgcctctc ggtgatgcag ggggcggtca aatatctcgg atacgctgat
     5761 gaacattgct ctgagccgga agagatcatg gtgatcaatg ccggcgagtt tggcgtgttt
     5821 cctccggaaa agtggcacaa tattgaggtc atgacggatg atacctattt taacatcgac
     5881 ttttttgtcg cgccggaagt actgatggaa ggggcgacct cacgaaaagt cattcatgcc
     5941 gggagagaat aataatggga aaagctactt ataccgtcac ggtcacgaat aatagcaacg
     6001 gcgtctctgt ggactatgaa acggaagcac cgatgacgtt gctggtacct gaagttacag
     6061 cagaagttgt gaaggatttg gtcaataccg tgcgttccta cgataccgaa aacgaacacg
     6121 acgtttgcgg ttggtaaaga tgctgtagta tctatttgat ataaaatgat tctttaaatg
     6181 agaagccgca tcgcgcgtcg ccagcgtgat gcggtttttg cgtattgaaa agcgctgttt
     6241 atttacatca gacatgggtt gaaaagaaac attaag
//
LOCUS       DAJVBX010000228         6135 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.228, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000228 DAJVBX010000000
VERSION     DAJVBX010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 6135)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6135)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6135
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.228"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            333..592
                     /locus_tag="OPV72_004010"
                     /pseudo
     CDS             333..592
                     /locus_tag="OPV72_004010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005224849.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family transcriptional regulator"
     gene            589..1140
                     /locus_tag="OPV72_004011"
     CDS             589..1140
                     /locus_tag="OPV72_004011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004153681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host cell division inhibitor Icd-like protein"
                     /protein_id="HCR9916180.1"
                     /translation="MMMTIQQTAPFSGLLLFIVSRYSFPAVAKSAAGRGNPSNLTATP
                     DAPCVFFCVYALVHLLLAQWFHDLCSYRVMVAQAGPTSVGPVSVRAGISTPVWATTTE
                     RGNSGGSITCYLTEVALMATILTPSYPQFVFVFAAVRRADRKPRICMLRTVAGDEQAA
                     RLSLVRDYVLSFAGRLPVAEVRA"
     gene            1137..1364
                     /locus_tag="OPV72_004012"
     CDS             1137..1364
                     /locus_tag="OPV72_004012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916181.1"
                     /translation="MRHTTITARDLECLEHMRNVGQLVNELMQVQDCATVRRDPVQQS
                     QLTSVIYLMTAQLDGVVERCNQRWLTGEGNV"
     gene            1361..1681
                     /locus_tag="OPV72_004013"
     CDS             1361..1681
                     /locus_tag="OPV72_004013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005224852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5375 domain-containing protein"
                     /protein_id="HCR9916182.1"
                     /translation="MKNPLPPVLRAALYRRAVACAWLTLCERQHRYPHLTLDALESAI
                     AAELEGFYLRQHGEEKGRQIACALLEDLIEAGPLKAAPSLSFLGLTVMDELCARHITA
                     PVLH"
     gene            1696..4028
                     /locus_tag="OPV72_004014"
                     /pseudo
     CDS             1696..4028
                     /locus_tag="OPV72_004014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005224853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
     gene            4765..4905
                     /locus_tag="OPV72_004015"
                     /pseudo
     CDS             4765..4905
                     /locus_tag="OPV72_004015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008322911.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4102 domain-containing protein"
     gene            complement(4937..6086)
                     /locus_tag="OPV72_004016"
                     /pseudo
     CDS             complement(4937..6086)
                     /locus_tag="OPV72_004016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477168.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         1409 a         1707 c         1611 g         1408 t
ORIGIN      
        1 cagtgagtta aagggtgaat agttgaaggt ctgagtgttc accgtctgtt caccactgtt
       61 cacccttcac tttgttcagc cagccagctt cttagatttt ttagcgatta aaaaaagaaa
      121 tatataaaca aaagtaatca gcaatgggcc accggtttgc caacgtttgc caaaaaacgg
      181 ccaacgtttg ccactgtata aaaatcgctc tgttgtgtgg tggagtacta caaaatgact
      241 tgttgccctg cgtaaaaata ttcacaaaat agagagctac ccgaagccgg acggacacga
      301 ccggcactgt atggactttg tgaggtagcc cgatgcacac cgctttttct tccccgtctt
      361 ctgcccctgc cgcgccgctg atgccggttt ctgataccgt tcatgagcgt tttattcgtc
      421 tgcccgaagt gatgcatctg tgcggtctgt cccgctcgac catttacgac ctcatcagcc
      481 gggaagcctt cccgaaacaa atctccctcg gcggaaaaaa cgtggcgtgg gcgcagtctg
      541 aaatcacggc atggatgact gaccgcatcg caaccggggt tatgacgcat gatgatgacc
      601 attcagcaaa cagccccttt ttctggcttg cttcttttta tcgtttccag gtatagtttt
      661 cccgctgtcg caaaatcggc agccgggcgt ggaaacccga gtaatctaac ggcgacacct
      721 gacgcgccat gcgtcttttt ttgtgtctat gccctcgtgc acctgttact tgcgcaatgg
      781 tttcatgacc tttgcagcta tcgagtaatg gtggctcagg cggggccgac ttcggtcggg
      841 ccggtatccg ttagagccgg tatttccacc cccgtctggg ctaccaccac tgagcgtgga
      901 aactccggtg gtagcataac ctgctatcta acggaggttg cccttatggc tacgatcctc
      961 accccgtcat acccgcagtt tgtctttgtg tttgccgctg ttcgtcgcgc agaccgtaaa
     1021 ccccgtatct gtatgcttcg caccgttgcc ggtgatgaac aggccgcacg tctttccctc
     1081 gttcgcgatt acgtcctctc gttcgctggt cgtctgccgg ttgcggaggt gcgcgcatga
     1141 gacacaccac cattaccgcc cgtgacctcg aatgtctgga gcatatgcgc aacgtcggcc
     1201 agctcgtcaa tgagctgatg caggtgcagg actgcgccac cgttcgtcgc gacccggtgc
     1261 agcagtcaca gctcacctcg gtgatttacc tcatgaccgc ccagcttgac ggcgtggtag
     1321 agcgctgcaa tcagcgctgg ctgaccgggg agggcaacgt atgaaaaatc cattaccgcc
     1381 cgtattacgc gccgcgctgt atcgtcgcgc cgtggcctgt gcctggctga ccctgtgcga
     1441 acgccagcac cgctatccgc acctcaccct cgacgcgctg gaaagcgcca ttgccgccga
     1501 gctggagggc ttctacctgc gccagcacgg agaggaaaaa ggccgccaga ttgcctgtgc
     1561 actgctggaa gatttaatag aagccgggcc acttaaggcc gcaccgtcgc tgtcctttct
     1621 cgggctgacc gtgatggatg agctttgcgc ccgtcatatc accgcaccgg tactgcactg
     1681 agggagaaaa taaacatgaa aatgaacgta acggaaacgg taaaacaagc ctgcggccac
     1741 tggtcgcgta ttctcccggc gctgggtgtg aaggtgatta aaaaccgcca tcaggcctgt
     1801 ccggtgtgcg gcggctctga ccgtttccgc tttgacgata aagagggacg cgggacgtgg
     1861 ttctgcaacc agtgcggcgc gggtgacggg cttaagctgg ttgagaaggt atttggcgtg
     1921 tcggcctccg aggccgccgg aaaggtggat gccgtgaccg gcaacctgcc gccggttgcc
     1981 ctggaagtga ttgcggccgc agaagcagaa acggaggctg accgcaaagc ggcggccgcg
     2041 ctggccgtaa agctcatgga gaaaacccga ccggccagcg gcaacgccta cctcacccgc
     2101 aagggattcc ccggtcatga gtgtgtcatg ctgacggcca cacacaaaac cggcggcgtg
     2161 acgttccgcg ccggtgatat ggttgtcccg ctgtatgaca atgccggggc gctggttaac
     2221 gttcagctta ttaattctga cggtctcaaa cgcaccctga aaggcggggc ggtaaaagga
     2281 gcgtgtcaca ccatcgaagg gaaaaacagg cgggaaaacg cctgtgggtt gcggagggct
     2341 atgcgaccgc gctcaccgta catcacctga ccggggaaac cgtcatggtg gcgctgtcct
     2401 ccgtgaacct actttctctg gcgagccttg cccgtcagaa acacccggcc tgtcagattg
     2461 tcctcgccgc cgaccgtgac cttaacggca acggccagag taaagccgct gcggccgcag
     2521 acgcctgcga gggcattgtc gccctgccgc cggtgttcgg tgactggaat gatgcgttta
     2581 tgcagaaagg tgaagaggcc acgcggaaag ccatttatga cgccatccgg cctccggctg
     2641 acagcccttt cactaccatg agcgaagcgg aatttaccgc catgagcacc agtgaaaagg
     2701 caatgcgggt gcatgaacat tacggcgaag cgctggccgt ggatgcgaac ggccagctcc
     2761 tgtcccgata tgaggcagga atatggaaaa tcattccccc gtcggatttt gcccgcgacg
     2821 tggccgggtt gtttcagcgt ctgcgcgccc cgttctcgtc ggggaaaatt gcctcagtgg
     2881 tggagaccct gaaactgatt attccgcagc aggacgcacc ggcgcgccgt ctgattggtt
     2941 ttcgtaacgg ggtactcgat accgccaccg gcactttcag cccgcaccac aaatcgcact
     3001 ggctgcgcac gctatgtgat gttgatttca cctcaccggt ggagggcgaa acgctggaaa
     3061 cccacgcccc tcatttctgg cgctggcttg accgcgctgc cggtggcaaa ccggaaaaac
     3121 gcgatgtgat tctggccgcg ctgtttatgg ttctggcgaa ccgttacgac tggcagctct
     3181 ttctcgaagt caccggcccc ggcgggagcg gaaaaagtat tctggccgaa attgcgacca
     3241 tgcttgccgg ggaagataac gccacgtcgg ccaccatcga aacgctggaa tcaccccgcg
     3301 aacgcgctgc gctgattggc ttctctctga tacgactgcc tgaccaggaa aaatggagcg
     3361 gtgacggggc aggactcaag gccatcaccg gcggggatgc ggtctccgtt gacccgaaat
     3421 acaaggatgc gtactccacc catattccag cggtgattct ggccgtgaac aataacccga
     3481 tgcgctttac cgaccgcagc ggtggtgtat cgcgccgccg ggtgattatt cacttcccgg
     3541 agcagattgc cccggaggaa cgcgacccgc agctcaggga taaaattgcg cgcgagctgg
     3601 ccatcattgt gcgtcagctt atgcagaagt tcagcgaccc gatgacagcg cgcacactgc
     3661 tccagtcaca gcagaactcc gacgaggcac tcagtatcaa gcgcgatgct gacccgacgt
     3721 ttgatttttg cggctatctg gaaatgctcc cgcagaccaa cgggatgttt atgggtaatg
     3781 ccagtattat cccgcgtaat taccgtaaat atctttatca cgcgtatctg gcctatatgg
     3841 aggctaacgg gtacaggaac gtgctcagcc tgaaaatgtt cgggctgggg ctgcccatga
     3901 tgctgaaaga atacggcctg aattatgaga agcggcacac aaagcagggg atacaaacca
     3961 atctgtcgct gaaagaggaa agctacggcg actggctgcc gaaatgcgag gaacccgcag
     4021 caacataacc aactccagac cggcaacagc cggtcttttt ctttctggac attgccacag
     4081 ggtgaacact ccactgttca cccttcaccg tatattcacc ctgtatcacc atgaaattat
     4141 tgataaaaaa ccagaggtga acagtgtgaa caataaaacc tgaaaaaact ttttatcacc
     4201 ctgcgcatcg cctgaccagg cgcatccagg acgagcaaaa atcacaaatg tgaagagtcg
     4261 attgttcact cttcaccaac tcatcaccac ttatcaccat gatattaaaa agaaaagtga
     4321 agaggtgaac agtgtgaaca gttatatgga aaaaaagaat tttactgatg ttcaatatta
     4381 ccccggttag gatccgtata tcggaaccta accgatgggg aaaataacaa tttccttttt
     4441 aataccaatc agttgtgaac ttaaggggct taaaaagcca tgggggcaca aaagggggca
     4501 catgaacatg tgttcttctt tatttccttt attttcaatt tattatgttg tgttttgagt
     4561 ccggccttcg caccatacaa agcttttttc aagtctacta acgtctactt taatccacaa
     4621 aaacagtaag ttaagcgaat ttctgacttg gcttagtctg ttcacgtcta ctcaattcct
     4681 tgaacatata ccaaccgatg atggtataac tgatggtatt cccggttcga ttgattttgg
     4741 taccaacact ggaggtatca actgatggct ctcaccgata tcaaagttag gactaccaag
     4801 ccctccgaca aacccttcaa actcacagat gggcagggta tgcacctgct gatcaacccc
     4861 aatggttcaa aatactggca actccaatac cgtttcgggg gtaaactgat cctacccgcg
     4921 taatagggat acaaccttaa gcgcggttct ggttttcaaa ttgttccgga ctgagaccgc
     4981 cacaggcact gtggcgacgc cagcgattgt aatcgcactc aatataatta aacactgctg
     5041 cccgcattat ttcccggctg gcaaagtcct ctccatgcat acattccacc ttcagcgtgt
     5101 ggaagaagct ttccgcacag gcattatcgt aacaacagcc tctggcgctc atcctgcccc
     5161 gcagattatg ccgtttcagt aagctctggt aatccgctga acagtactta ctgcctctgt
     5221 ctgtatatat ggtgactttt ccggtcgttt acgccgccac agcgctatgt gtaatgcatc
     5281 gcaggcaaac tgtgccgtca tccgcgagga catagaccag ccagtggctg actgcggcca
     5341 caggtcaata accacggcca gataaagcca gccttcaccg gtgcgaagat acatgatgtc
     5401 acccacccat ttctgattcg ggccactgac gtaaaagtcc tgcttcagca gattctctgg
     5461 actggcagac catgttcgcg gtaactgact ggactgatct tccgtgaagc tttcgcccgc
     5521 agcgcctgcc ggcgcaggct ggccgctacg gtatacaccc gtccctgagc acgaagctca
     5581 tccgtcaggc gtggcgcacc atagcgctgt ttgcgtcact gaatgcctcc cgggcgacgt
     5641 tatcacagac aaggcggaac tgctgacgct ggtttatctg atgacgacgc tgatgccaga
     5701 cgtaccagcc actacgggca acctgaagta cacggcacat ggctttgata ctgaactcag
     5761 cctgatgttt ttcgatgaag acatacttca tttcaggcgt ttcgcgaagt atgtcgcgac
     5821 cttctggaga atagtcagtt cctcatcccg ttctgccagt tgatgcttca gacggacgat
     5881 ctctgcggac atctcctatt cgcgttcaga agaagagagc tgattttgct gttttcttcg
     5941 ccagttgtag agctgcgatt catacaggtt aagctcgctg gtagccgcag ccatcccaat
     6001 gcgttagcca gtttcaaggc ttcgtcgcga aattcaggcg tatgttgctt gcatggcttt
     6061 ttggtggttg atgctgcttt tgtcatgtga gacacctctt tcttgagagt ttactcactt
     6121 agtcgcatgt ccact
//
LOCUS       DAJVBX010000229         6077 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.229, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000229 DAJVBX010000000
VERSION     DAJVBX010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 6077)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6077)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6077
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.229"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            3..515
                     /locus_tag="OPV72_004017"
     CDS             3..515
                     /locus_tag="OPV72_004017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010670706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HCR9916183.1"
                     /translation="MITGSLLVSSSAMAVSDNTITFQGEVSDETCSVVINGNQAKPVV
                     LLPTVSTKELSEQGKTAGPITFDIGLSGCTGSKDKTTKISTVFVGNQVTSNGNLGNTG
                     SAKNVEVQLLDTSGEPINLTGGFTGDGDLQLEPNASEASATYTARYYSTGKAEAGTVA
                     ATLQYAVSYK"
     gene            577..1338
                     /locus_tag="OPV72_004018"
     CDS             577..1338
                     /locus_tag="OPV72_004018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone"
                     /protein_id="HCR9916184.1"
                     /translation="MKMDTRHSALYYLIVFLLLALPATASWASVTILGSRIIYPSTAS
                     SVDVQLKNNDAIPYIVQTWFDDGDMNTSPENSSAMPFIATPPVFRIQPKAGQVVRVIY
                     NNTKKLPQDRESVFWFNVLQVPPTNIGSDSGKNKMLVMLRSRIKLFYRPDGLGKPDNL
                     AKKLQIKTVNKGSGKSGIVIVNPQPWFASLSNLNVKVNGASYNLDADMIAPFSSQTWW
                     LPGKRSLKSFSGTVTVTLVNDLGARISESYDVPHH"
     gene            1322..3883
                     /locus_tag="OPV72_004019"
     CDS             1322..3883
                     /locus_tag="OPV72_004019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial outer membrane usher protein"
                     /protein_id="HCR9916185.1"
                     /translation="MSPTINLNRKSLALLIAIVCSGSAQGEEYYFDPALLQGATYGQN
                     IARFNEQQTPSGDYLADVYVNGTLVASSTNIRFNAVKEGQQAEPCLPLSVMKAAQIKS
                     LPETDAATECRPLREWVPHAGWQFDSATLRLLLTIPMTELTHKPRGYISPSEWDSGAL
                     ALFLRHNTNWTHTENTDSHYRYQYLWSGLNMGVNLGLWQVRHQSNLRYANSNQSGSAW
                     RYNSVRTWVQRPVASINSILSLGDSYTDSSLFGSLSFNGVKLVTDERMRPQGKRGYAP
                     EVRGVAASSAHVVVKQLGKVIYETNVPPGPFYIDDLYNTRYQGDLEVEVIEASGKTSR
                     FTVPYSSVPDSVRPGNWHYSLAFGRVRQYYDIENRFFEGTFQHGVNNTITLNLGSRIA
                     QRYQAWLAGGVWATGMGAFGLNATWSNARAEHNERQQGWRAELSYSKTFTTGTNLVLA
                     AYRYSTNGFRDLQDVLGVRREAKTGIDYYSDTLHQRNRLSATVSQPLGRLGTLNLSAS
                     TADYYNNQSRITQLQMGYSNQWRNISYGVNIARQRTTWDYDRFYHGVNEPLDVSSRQK
                     YTETTMSFNVSIPLDWGENRTSVAMNYNQSSQSRSSTVSMTGSSGENSDLSWSVYGGY
                     ERYRNSNSDSSAPTTFGGNLQQNTQFGALRANYDQGDNYRQEGLGASGTLVLHPGGLT
                     AGPYTSDTFALIHADGAQGAIVQNGQGAVVDRFGYAILPSLSPYRINNVTLDTRKMRS
                     DAELTGGSQQIVPYAGAIARVNFATISGKAVLISVKMPDGGIPPMGADVFNGEGTNIG
                     MVGQSGQIYARIAHPSGSLLVRWGTGANQRCRVAYQLDLHTKEPFLYLNKICEKE"
     gene            3888..5213
                     /gene="stbD"
                     /locus_tag="OPV72_004020"
     CDS             3888..5213
                     /gene="stbD"
                     /locus_tag="OPV72_004020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial usher protein StbD"
                     /protein_id="HCR9916186.1"
                     /translation="MLFSFRTLLFITSLFVSAGTWSSCIKVTDKSALSDAAIKAGYTA
                     QNWIGALDTNTGNIGLPTVISISNSETFQPSGTLLASGIGNFLTAATGTPYSSKQVLY
                     RCDSADAGKLYEMYSTNGDSAFAGAFFTPEVEGAYYDVERNVAVRMTNLSTGEYYSRF
                     WKERQLTADSWFQDDKYIYIPASAFSNVLYEMFKIDSRKYFAYQNPMDRDTWTQPRGY
                     IAFKGPGLITERIKAGLDHASDYYGWPSYWPGAWSTYNSVTYVRGALCKITDYPAIVK
                     IPPVAVGILAAGGNSQAPFHVSLECESGAVSSALPSTSAANVAMGFVVNQPTAVAAAR
                     RLGLTTSAGGLSWLLDTHYGEPGVASGVGIRIYNDAGTPINLLPDRIKTGTGNARGWY
                     GYKDLTTRVSSGSVETYSGDFTASLEALGGQTVTAGSVNAQLQAVVSFQ"
     gene            5179..5937
                     /locus_tag="OPV72_004021"
     CDS             5179..5937
                     /locus_tag="OPV72_004021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial assembly chaperone"
                     /protein_id="HCR9916187.1"
                     /translation="MRNYRQWLVFSKVILTLLGLTGWYGPAQAAVNIDRTRIIFASDE
                     VAQSLTLSNDNTTPMLLQVWTDAGNIDASPDNSKTPLVALPPVFKMQPGELRTLRLLL
                     SSRQQLATDRESLFWLNIYQIPPVTQDIKNHPRKLVLPLRLRLKILIRPTGLKAPTEA
                     EEKKLRFIAKENTIRIVNPTSWYMSLTLTMDNKKSIGDIMVAPKTALDVPLTRSPTPG
                     ASINYAVINDSGNWRQYTAILEKYISKSNFIPEF"
BASE COUNT         1567 a         1558 c         1533 g         1419 t
ORIGIN      
        1 caatgatcac aggctcgctt cttgtctcca gcagcgcgat ggctgtttct gataacacca
       61 tcacctttca aggggaagtc tctgatgaaa cgtgctctgt cgtgattaat ggtaatcagg
      121 ctaaacccgt cgtgttattg ccaacagtaa gtactaaaga gttatcagaa caagggaaaa
      181 ccgcggggcc aataacgttt gatattgggc tgtccgggtg taccggttct aaggacaaaa
      241 caacaaaaat ttccaccgtc tttgtcggta atcaggtcac cagtaacggt aacctgggta
      301 atactggcag cgcgaaaaat gttgaagtcc aattactcga cacttcaggg gagccaatca
      361 atctgaccgg cggctttact ggcgacggcg acctacagct ggaaccaaat gcttctgaag
      421 cgagcgcgac ttataccgcg cggtattact ctaccgggaa agcagaggct gggacagtcg
      481 ctgccaccct acaatacgcc gtttcgtata aataattgtc gctacggtct ggcattgaaa
      541 cgccagacca ttttcaatcg ccagggagtt gttgagatga aaatggatac ccgacattcc
      601 gcattatatt acttaatagt ttttctattg ctggccctac ccgccacagc atcgtgggcg
      661 agcgttacta ttttgggtag ccgaataatt tacccatcaa cagcctcctc cgtagatgtg
      721 cagttaaaaa ataatgatgc aataccttat atcgtacaaa cctggtttga tgatggcgat
      781 atgaatacca gcccggaaaa tagcagcgcg atgccgttta ttgccacgcc gccagtattt
      841 cgtattcaac ccaaagcagg ccaggtggta cgcgtaattt ataacaacac aaaaaaattg
      901 ccgcaggatc gtgaatcagt attctggttt aacgtattac aggtgccacc aacgaatatt
      961 ggcagcgaca gcgggaaaaa taaaatgttg gtgatgctac gctcaagaat aaagcttttc
     1021 tatcgtcctg acgggctagg taaacctgat aatctggcga aaaaactaca gattaaaacg
     1081 gtaaataagg gttctggaaa aagcggtatt gttatcgtta atccgcagcc ctggtttgcc
     1141 tctttaagta acctgaatgt aaaagtgaac ggcgcttcgt ataacctgga tgcagacatg
     1201 attgcccctt tttccagtca aacctggtgg ctgccgggca aacggtcact caaatccttc
     1261 tccggtacag tcaccgttac tttggttaac gacctgggcg caaggataag cgagagctac
     1321 gatgtccccc accattaatt tgaaccgcaa aagccttgcg ctattgatcg ccatagtttg
     1381 ctcaggctcc gcgcagggtg aagagtatta ttttgatcct gcgctacttc agggggccac
     1441 ttacggacaa aatattgccc gttttaatga acagcaaacg ccttccggag actatcttgc
     1501 cgacgtttac gttaatggca cgctggtagc ctcgagcact aatattcgat ttaatgctgt
     1561 aaaagagggt caacaggctg aaccctgcct gcccttatcg gtgatgaaag cggcacaaat
     1621 aaaatcactc cccgagaccg acgctgcgac cgagtgtcgc ccgctcaggg agtgggtacc
     1681 tcatgccggc tggcaatttg atagcgccac gcttcgcctg ttgctgacga ttccaatgac
     1741 cgaacttacg cacaaaccgc gcggttatat ctccccttca gagtgggata gcggcgcgct
     1801 ggcgctgttt ttacgccata acacaaactg gacccacacc gaaaataccg atagccatta
     1861 tcgctaccaa tacttatgga gcggtttaaa catgggcgtt aacctcggac tttggcaggt
     1921 ccgtcatcaa agtaatctgc gctatgccaa tagcaaccag agcggaagcg cctggcgcta
     1981 taatagcgtt cgaacctggg tgcaaagacc tgtcgcatct attaacagta tcctgtcgct
     2041 gggcgatagc tatacggact ccagcttatt cggcagtctg tcctttaacg gagttaagct
     2101 tgtcaccgac gagcggatgc gccctcaggg caaacgcggt tatgcgccgg aagttcgggg
     2161 cgtagcggcc agtagcgcgc acgtggtagt aaaacaactg gggaaagtga tttatgaaac
     2221 caacgttccg ccgggcccat tttatattga cgatctgtac aacacccgtt atcaaggcga
     2281 tctggaggta gaggttatcg aggccagcgg taaaacctca cgtttcaccg tgccttattc
     2341 ttccgtgccg gattcggtac gtcccggtaa ctggcactat tcgctggcct tcggcagggt
     2401 tcgtcagtac tacgatattg aaaatcgttt ctttgaggga acgttccagc acggcgttaa
     2461 taacaccatt accctcaacc tcggttcacg aattgcgcag cgttaccagg catggctggc
     2521 gggcggcgtc tgggccaccg gtatgggcgc gttcggcctt aacgccacct ggtcgaatgc
     2581 gcgcgcagag cataacgagc gccaacaagg ctggcgcgcg gaactcagtt acagcaaaac
     2641 gtttaccacc ggcactaacc tggtactggc ggcttatcgt tattcaacca acggctttcg
     2701 cgatcttcag gacgtgctcg gcgtacgccg ggaagcaaaa acggggattg attactactc
     2761 cgacacgctg catcaacgca atcgcctgtc cgcgacggta agccagccgt taggacggct
     2821 tggcacgctt aacctcagcg ccagcaccgc agactactac aataaccaat cgcgtataac
     2881 acagctacaa atggggtata gcaaccagtg gcggaatata agctacgggg tgaatatcgc
     2941 gcgacagcgc accacctggg attacgatcg cttttatcac ggcgttaacg aaccactgga
     3001 cgtgagtagc cgacaaaaat ataccgaaac cacaatgtcg tttaatgtct ctataccgct
     3061 ggattggggc gaaaacagaa cgtctgtcgc tatgaattat aaccagtcca gtcaaagccg
     3121 ttcctcaacc gtatccatga ccggcagtag cggtgaaaac agcgacctgt catggtcggt
     3181 ttatggcggc tacgagcgtt atcgcaatag taatagcgat agcagcgcgc caacgacgtt
     3241 tggcggtaat ctacaacaaa acacccagtt tggcgcactt cgcgccaact atgaccaggg
     3301 tgataactat cgtcaggaag gactgggcgc gtccggcacc ctggtactcc accctggcgg
     3361 tctgacggct ggcccctata ccagcgatac ctttgcgctt attcatgccg atggcgcgca
     3421 gggcgcgatc gtacaaaatg gccagggcgc tgtggttgat cgctttggtt acgccattct
     3481 gccttcgtta tctccttacc gcatcaataa cgttacgctc gacacccgta agatgcgcag
     3541 cgatgccgaa ctgacgggag gaagtcagca gattgtgccc tatgccggcg ccatcgcgcg
     3601 tgtcaatttc gccactatca gcggcaaagc ggtgctgatc tccgtgaaga tgccggatgg
     3661 cggcataccg ccaatgggcg ctgatgtttt caacggtgaa ggcacaaaca tcggcatggt
     3721 cggccagagt gggcagattt atgcccgaat cgcccatccg tcgggttctc tactggtgcg
     3781 ctggggaaca ggggcaaacc agcgttgccg ggttgcctac caactcgatc ttcacaccaa
     3841 agaaccgttt ctctatctga acaaaatctg cgagaaggaa tagcacaatg ctttttagtt
     3901 tccgaacgct cttgtttatc accagtctgt tcgtcagcgc cggaacatgg tcgtcatgta
     3961 taaaagtcac cgataagagc gcgctctctg acgcggcgat aaaagcgggc tacacggcgc
     4021 aaaactggat cggcgcactt gacacgaata cgggtaatat cggtttgcca acggtgatta
     4081 gcatcagtaa tagtgaaaca tttcaaccct ccggcacact attggccagt gggatcggta
     4141 acttcctgac ggccgccacc ggaacgccct attccagtaa acaggtactt taccgctgcg
     4201 attccgccga tgccgggaag ctctatgaga tgtattcgac aaatggcgat agcgcttttg
     4261 cgggggcatt ttttactccc gaagtagaag gcgcctatta tgatgtggag cgtaatgtcg
     4321 ctgtccgtat gacaaacctc agtaccggcg aatattacag ccgcttctgg aaagaacgcc
     4381 aacttaccgc agacagttgg tttcaggatg acaaatatat ttatattcct gccagcgcgt
     4441 ttagcaacgt gttatatgag atgtttaaaa ttgactcaag aaaatatttt gcctaccaga
     4501 atccaatgga ccgagatacc tggacgcagc ctcggggtta tatcgcgttt aaaggcccag
     4561 gcttgattac cgagcggatc aaagcgggac tggatcatgc cagcgattat tatggctggc
     4621 ccagctattg gcccggggca tggagtacat ataatagcgt cacctatgtt cgcggcgcgt
     4681 tatgtaaaat cacagattat cctgcgatcg tgaaaattcc ccctgtcgcc gtcggcatat
     4741 tagccgccgg aggcaatagt caggcgcctt tccacgtcag cctagaatgt gagtccggtg
     4801 ccgtgtccag tgccctcccg tccaccagcg ccgctaatgt cgcaatgggg tttgtcgtta
     4861 atcaacccac cgccgtggcg gcggcgcgtc gcctggggct aaccacatct gcaggcggtc
     4921 tgtcgtggct actggacacc cattatggcg aacctggcgt agcttccgga gtgggtatcc
     4981 gcatctataa cgatgccggt acgccgatta acctgttacc cgatcggatc aagacaggca
     5041 ctggcaacgc ccgaggctgg tatggctata aagatttaac cacacgggta tcatccggtt
     5101 cagtagaaac ctatagcggt gattttactg cctcgcttga ggcgctcggc ggacaaacag
     5161 taacggcagg aagcgtgaat gcgcaattac aggcagtggt tagttttcag taaagtcata
     5221 ttaacgctac ttgggttgac gggatggtat ggcccggcac aagctgccgt taatattgac
     5281 agaacccgaa ttatttttgc ttcagatgag gtcgctcaat cgttgacatt atccaacgat
     5341 aatacaacgc cgatgctgtt acaggtatgg accgacgccg gaaacattga cgcctctccg
     5401 gataacagca aaacgccgct ggtggcgctg ccgccggtat ttaaaatgca gccaggagaa
     5461 ctgagaacgc ttcgcctgct cctgagttcc cgccagcagc tggcaacgga ccgggagagt
     5521 ctcttctggc taaacattta tcagataccg ccagtcaccc aggacattaa aaaccacccg
     5581 cgaaaactgg tgttaccgct tcgtttgagg ctaaaaattt taattcgccc gactgggcta
     5641 aaagcgccca cggaagcgga ggagaaaaaa ttacgcttta ttgctaaaga gaatactata
     5701 cggatagtta accccacctc gtggtatatg agtttaacgt taacgatgga taacaagaaa
     5761 agtatcggcg atatcatggt tgcgccgaaa acagcacttg atgtgccgct aacacgctcg
     5821 ccaacgccgg gagcatcgat aaattatgca gtaatcaatg attccgggaa ctggcgacaa
     5881 tataccgcca tactggaaaa atatattagt aagagtaatt ttattcctga gttttgatgg
     5941 gaaatattca gggatacgat cgtatccctg agacaggcca gaattcagca tgtaccattg
     6001 tcaaaaatag cattaagctg atattttact ttttgcacgg catctttgtt ctgttgagtt
     6061 cccttctcct caacaga
//
LOCUS       DAJVBX010000230         6016 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.230, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000230 DAJVBX010000000
VERSION     DAJVBX010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 6016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6016
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.230"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            310..1239
                     /locus_tag="OPV72_004022"
     CDS             310..1239
                     /locus_tag="OPV72_004022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462239.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HCR9916188.1"
                     /translation="MQLQKLVNMFGGDLLRRYGQKVHKLTLHGGFSCPNRDGTIGRGG
                     CTFCNVASFADEAQQHHSIAEQLAHQAHLVNRAKRYLAYFQAYTSTFAEVQVLRSMYQ
                     QAVSQASIVGLCVGTRPDCVPQAVVDLLCEYKDQGYEVWLELGLQTAHDKTLRRINRG
                     HDFACYQRTTRIARERGLKVCAHLIVGLPGEGQAECLQTMERVVETGVDGIKLHPLHI
                     VKGSTMAKAWEAGRLNGIELDDYTLTAGEMIRHTPPEVIYHRISASARRPTLLAPLWC
                     ENRWTGMVELDKYLNEHGVQGSALARPWIPPVA"
     gene            1332..3668
                     /gene="arcB"
                     /locus_tag="OPV72_004023"
     CDS             1332..3668
                     /gene="arcB"
                     /locus_tag="OPV72_004023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aerobic respiration two-component sensor
                     histidine kinase ArcB"
                     /protein_id="HCR9916189.1"
                     /translation="MKQIRMLAQYYVDLMMKLGLVRFSMLLALALVVLAIVVQMAVTM
                     VLHGQVESIDVIRSIFFGLLITPWAVYFLSVVVEQLEESRQRLSRLVQKLEEMRERDL
                     KLNVQLKDNIAQLNQEIADREKAEAELQETFEQLKVEIKEREEAQIQLEQQSSFLRSF
                     LDASPDLVFYRNEDKEFSGCNRAMELLTGKSEKQLVHLKPEDVYSPEAAEKVIETDEK
                     VFRHNVSLTYEQWLDYPDGRKACFEIRKVPYYDRVGKRHGLMGFGRDITERKRYQDAL
                     ERASRDKTTFISTISHELRTPLNGIVGLSRILLDTDLTAEQEKYLKTIHVSAVTLGNI
                     FNDIIDMDKMERRKVQLDNQPVDFTSFMADLENLSGLQAQQKGLRFVLEPTLPLPHKV
                     ITDGTRLRQILWNLISNAVKFTQQGQVTVRARYDEGDMLHFEVEDSGIGIPQDEQDKI
                     FAMYYQVKDSHGGKPATGTGIGLAVSRRLAKNMGGDITVSSLPGKGSTFTLTVHAPAV
                     AEEVEDAFDEDDMPLPALHVLLVEDIELNVIVARSVLEKLGNSVDVAMTGKAALEMFA
                     PGEYDLVLLDIQLPDMTGLDIARELTRRHTREDLPPLVALTANVLKDKKEYLDAGMDD
                     VLSKPLSVPALTAMIKKFWDATDKEESTVTPEESDKAQALLDIPMLEQYIELVGPKLI
                     TDGLAVFEKMMLGYLSVLESNLTARDKKGVVEEGHKIKGAAGSVGLRHLQQLGQQIQS
                     PDLPAWEDNVVEWIEEMKQEWQHDVAVLKAWVANAEKK"
     gene            3895..4548
                     /gene="elbB"
                     /locus_tag="OPV72_004024"
     CDS             3895..4548
                     /gene="elbB"
                     /locus_tag="OPV72_004024"
                     /EC_number="4.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenoid biosynthesis glyoxalase ElbB"
                     /protein_id="HCR9916190.1"
                     /translation="MKKIGVVLSGCGVYDGTEIHEAVLTLLAIARSGAQAICFAPDKP
                     QADVINHLTGEAMAETRNVLIEAARITRGDIRPLSQAQPEELDALIVPGGFGAAKNLS
                     NFASKGSECRVDSDVVALAKAMHQSGKPLGFICIAPAMLPKIFDFPLRLTIGTDIDTA
                     EVLEEMGAEHVPCPVDDIVVDEDNKVVTTPAYMLAQDIAQAASGIDKLVSRVLVLAE"
     gene            4545..5273
                     /gene="mtgA"
                     /locus_tag="OPV72_004025"
     CDS             4545..5273
                     /gene="mtgA"
                     /locus_tag="OPV72_004025"
                     /EC_number="2.4.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monofunctional biosynthetic peptidoglycan
                     transglycosylase"
                     /protein_id="HCR9916191.1"
                     /translation="MSKRRIAPLTFLRRLLLRILAALAVFWGGGIALFSVVPVPFSAV
                     MAERQISAWLGGEFGYVAHSDWVSMADISPWMGLAVIAAEDQKFPEHWGFDVPAIEKA
                     LAHNERNESRIRGASTLSQQTAKNLFLWDGRSWVRKGLEAGLTLGIETVWSKKRILTV
                     YLNIAEFGDGIFGVEAAAQRYFHKPASRLSVSEAALLAAVLPNPLRYKANAPSGYVRS
                     RQAWIMRQMRQLGGESFMTRNQLN"
     gene            complement(5348..5980)
                     /gene="yrbL"
                     /locus_tag="OPV72_004026"
     CDS             complement(5348..5980)
                     /gene="yrbL"
                     /locus_tag="OPV72_004026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoP regulatory network protein YrbL"
                     /protein_id="HCR9916192.1"
                     /translation="MILLSKQTPLGAGRHRKCYTHPDNARRCIKVIYNRDHGGDKEIR
                     RELSYYAHLSRYLTDWSAIPRYYGTVETDCGTGYVYDMITDFNGAPSITLTEFAAQCR
                     YEEDVAVLRRLLKKLKRYLLDNHIVTMSLKPQNILCQRISESEVVPVVCDNLGESTFI
                     PLATWSTWCCERKLERVWQRFIAQPALAVALERDAQPKDKKRLALTSHEA"
BASE COUNT         1407 a         1416 c         1771 g         1422 t
ORIGIN      
        1 atctgtctca ctataagagc cgctcgccag gagttatctg accttgcttt ttcaaaaatc
       61 ttggcatttt atgctgtttt aagcgtgaac agcattgaat gctactgttt ttatcgatga
      121 cccagcagac gctgaaaaaa gaggggaata tcaggaaaaa tcatcagcgg gattatgaat
      181 gaaatatcgt ttattttgct tgattatgca atggataaaa gccttccggg acgattgatc
      241 caggtcatcg ccaaaggaga ctaaaaatgg caggctttgg cctcttttta agaggcggtc
      301 tatcagatta tgcagttaca gaaattagtc aatatgtttg gtggggatct tttacgtcgg
      361 tatgggcaaa aggttcataa gctgacgctt catggcggtt ttagctgccc taatcgcgac
      421 ggcaccatcg ggcgtggcgg ttgcaccttc tgtaatgtcg cctcttttgc cgatgaggcg
      481 cagcagcatc attcgattgc cgagcagctt gcgcatcagg cgcatctggt gaaccgcgct
      541 aaacgctatc tggcctattt ccaggcctac accagcacct ttgcagaagt gcaggtgctg
      601 cgttccatgt atcaacaggc ggtcagccag gccagtatcg tcgggttatg cgtcggtacg
      661 cgtccggatt gcgtcccgca ggcagtagta gatttactgt gtgaatataa agatcaaggc
      721 tacgaggtgt ggctggaact gggattgcaa accgcgcacg ataaaaccct gcgccgaatt
      781 aaccgcgggc atgacttcgc ctgctatcag cgtaccaccc ggattgcccg ggagcgcggg
      841 ctgaaagtgt gcgcgcatct gattgtgggg ctgccgggag aagggcaggc agaatgcctg
      901 caaaccatgg agcgtgtggt ggagacgggc gttgacggta ttaaactgca tccgctgcat
      961 attgtgaaag gcagtacgat ggccaaagcc tgggaagcgg ggcggctgaa cggcatcgaa
     1021 ctggacgact acacgctaac ggcaggtgag atgattcgtc atacgccgcc ggaggtaatt
     1081 tatcaccgaa tttcagccag cgctcgccgt ccgacgctgc ttgccccgct gtggtgcgag
     1141 aatcgctgga cggggatggt tgagctggac aaatacctga atgagcatgg cgtgcagggc
     1201 tctgcgctgg cccgtccctg gataccacct gtagcgtagc gtgatgaggg ggctacgcat
     1261 atttcgcaca atattcaacg cggttcccat aattgggtat tatgtgcgaa gttgtggtga
     1321 aggaatcctc tatgaagcaa attcgtatgc tggcgcaata ctatgtcgac ctgatgatga
     1381 aattgggtct ggtgcgcttt tccatgctcc tggcgttggc attggtggtg ctggcgattg
     1441 tcgtgcagat ggcggtgacc atggtgctgc atggtcaggt tgaaagtatc gacgttattc
     1501 gttccatctt ttttggcctg ttaattacgc cctgggcggt ctatttctta tccgttgttg
     1561 ttgaacaact ggaagagtca aggcagcgac tgtcgcgtct ggtgcaaaag ctggaggaga
     1621 tgcgcgagcg cgatctcaag cttaacgtac agttgaagga caatattgcc cagcttaatc
     1681 aggaaattgc cgatcgcgaa aaagcggaag cggagctgca agagacattt gaacagctaa
     1741 aagtagaaat taaagagcgt gaagaggcgc aaatccagct agaacagcaa tcctcttttc
     1801 tgcgctcctt tctggacgcc tcgccggatt tggtttttta tcgtaatgag gataaagagt
     1861 tttccggctg taaccgcgca atggaattgc taaccggcaa gagcgaaaaa cagctggtgc
     1921 atttgaagcc ggaagatgtg tactctcccg aagcggcgga gaaagtcatt gaaaccgatg
     1981 aaaaagtatt ccgccataac gtctccctga cctacgaaca gtggctggat tatccggacg
     2041 gacgaaaggc ctgctttgaa attcgtaaag tgccttatta cgaccgtgtc ggtaaacgtc
     2101 atggcctgat gggatttggt cgtgatatta ccgaacgtaa gcgttatcag gacgcgctgg
     2161 agcgcgccag tcgcgacaag accacattta tctctaccat cagtcatgag ctgcgcaccc
     2221 cgcttaacgg tatcgtcggt ttaagccgca tcctgctgga taccgatctt accgccgaac
     2281 aggaaaaata ccttaagaca atccatgtct ccgccgtgac gttaggcaat attttcaatg
     2341 atatcattga tatggataag atggagcggc gtaaggttca gcttgataac caaccggttg
     2401 atttcaccag ctttatggcc gatctggaaa acctttccgg tttgcaggcg cagcaaaaag
     2461 ggctacgttt tgtgcttgag ccgacgctgc cgctgccgca caaagtcatt accgacggaa
     2521 cgcgtctgcg ccagatttta tggaatttga tcagcaatgc ggtgaagttt actcagcagg
     2581 gccaggtgac ggtgcgggcg cgctatgatg aaggcgacat gctgcacttt gaagtggaag
     2641 attccgggat cggcattccg caggatgagc aggataaaat tttcgccatg tattatcagg
     2701 taaaagacag tcatggcggt aagccggcga cggggaccgg tatcgggctg gcggtctccc
     2761 gtcggctggc gaaaaatatg ggcggcgata ttaccgtttc cagtctgccg ggcaaaggat
     2821 cgacctttac gctaacggtt catgcgccag cggtggcgga agaggtggag gacgcctttg
     2881 atgaagacga catgccgctg cccgcgctgc atgttctgct ggtcgaagat attgaactga
     2941 acgtgattgt ggcgcgttca gtactggaaa aactggggaa cagcgtggat gtcgcgatga
     3001 ccggcaaggc ggcgctggag atgttcgcgc caggcgaata tgacctggtc ttactggata
     3061 ttcagctacc ggatatgacg ggtctggata ttgccagaga actgacccgt cgccacacgc
     3121 gggaagattt accgccgctg gtagcgctta cggctaacgt tctgaaagat aaaaaagagt
     3181 atctggacgc tggtatggac gatgtgctga gtaagccgct gtcggtgcca gccttaaccg
     3241 cgatgattaa aaaattctgg gatgccaccg ataaagagga gagtaccgtg acgcctgaag
     3301 agagcgataa agcgcaagcg ctgctggata tcccgatgct ggaacaatac atcgagttgg
     3361 ttgggcctaa attgatcacc gacggcctcg cggtgtttga aaaaatgatg cttggctatt
     3421 taagcgtgct ggagtccaat ctgacggcgc gtgacaaaaa aggcgtcgtt gaggaagggc
     3481 ataagattaa aggcgccgcc ggttcggtag ggctgcgtca tctgcaacaa cttggccagc
     3541 aaatccagtc gccggatctt cccgcctggg aagataatgt cgtggaatgg attgaagaga
     3601 tgaagcagga gtggcagcac gatgtcgcgg tgctgaaagc ctgggtggca aacgcggaaa
     3661 aaaaatgacc ccggtttgac cggggtgcgc gaatactgcg ccaacaccag ggaaatcgtg
     3721 gctgcgccgt gcttattatg atgatgtcaa aggcgcagtc ctgttttcag gccgcacgca
     3781 gttaagatag caaatcctaa atgatttgtt acatgaatca tttaaatgtg tgaagcgtag
     3841 cattttaatc aaaattatta atgggcttga gtcggttgca ggaggatgtt caccatgaaa
     3901 aaaattggcg tagtgctcag cggatgcggc gtctatgacg gcaccgaaat tcatgaggcc
     3961 gttctgacgc tgttggccat tgcccgcagc ggcgcgcagg ctatctgctt cgcgccggat
     4021 aaaccacaag cggatgttat taatcacctg accggcgaag ctatggcgga aacgcgtaac
     4081 gtcctgattg aggcggcgcg tattacgcgg ggcgatattc gtcctctgtc ccaggctcag
     4141 ccagaggaac tggatgcgct cattgtgcct ggtggtttcg gcgcggcgaa gaacctgagt
     4201 aatttcgcca gcaaggggag cgaatgccgg gtggatagcg atgtcgtcgc gctggcgaag
     4261 gccatgcacc agtccggcaa gccgctggga ttcatctgta tcgcgcccgc aatgttgccg
     4321 aaaatctttg acttcccgct acgtctgaca atagggacgg atattgatac cgctgaagta
     4381 cttgaagaga tgggggccga acacgtacct tgcccggttg atgatatcgt tgtggacgag
     4441 gataacaagg tcgtgaccac ccctgcctat atgctggcgc aggatatcgc ccaggcggca
     4501 agcggcattg ataaattagt gtcgcgcgtg ctggttctgg cggaatgagc aaacgacgca
     4561 tcgcgccgtt aacgtttttg cgccgtctac ttttacgtat ccttgctgcg ctcgccgtct
     4621 tttggggcgg cggcattgcg ctgtttagcg tggttccggt gcctttttcg gcggtgatgg
     4681 cggaacggca gattagcgcc tggctcggcg gagagttcgg ttatgtggcg cattctgact
     4741 gggtcagtat ggcggatatc tcgccgtgga tggggctggc ggtaattgcg gcggaagacc
     4801 agaagttccc tgagcactgg ggctttgatg ttccggcgat tgaaaaagcg ctggcgcata
     4861 atgagcggaa tgagagccgt attcgcggcg cctctacgct ttcgcagcaa acggcgaaaa
     4921 atctcttttt atgggatgga cgcagttggg tgcgcaaagg tctggaggcc gggctaacgc
     4981 tgggcattga aactgtctgg agcaaaaagc gcatcctcac ggtttatctg aatatcgcgg
     5041 agtttggcga tggtattttt ggcgtggagg ctgcggcaca acggtatttt cataaacctg
     5101 ccagtcgctt gagtgtgtct gaagccgcgt tgctggcggc ggtattgcca aatccgttac
     5161 gctataaggc gaatgcgcct tctggctatg tgcgtagccg gcaggcgtgg attatgcgcc
     5221 agatgcgcca actgggcggg gaatctttta tgacgcgcaa ccagcttaat taattttgcc
     5281 gattggcggc gcgaacgcct tatccggcct gcgatctgtg tcgtccaggc ctgataagca
     5341 caggccatta agcttcgtga gaagtaagcg ccagccgttt cttgtctttt ggctgcgcgt
     5401 ccctctccag ggcaacggcc agcgcaggct gggcgataaa ccgctgccac actctctcca
     5461 gtttgcgttc acagcaccat gttgaccagg tcgccagcgg gataaaggta ctttccccca
     5521 gattgtcgca aaccaccgga accacttctg actcgctgat acgctggcac aggatatttt
     5581 gcggcttcag cgacatcgtc acaatatggt tatccagcag gtaacgtttc agttttttca
     5641 gtagccgccg caggacagcg acatcctctt cataacgaca ttgcgcggcg aactcggtca
     5701 gggtaataga gggcgcgccg ttgaaatcgg taatcatgtc gtagacatag ccggtgccgc
     5761 aatcggtttc taccgtgccg taataacggg ggatagcgct ccagtccgtc aggtagcggg
     5821 acagatgcgc atagtagctc agttcacgcc gaatctcttt atcaccgccg tggtcacggt
     5881 tgtaaataac ttttatgcaa cgccgggcat tatccggatg cgtatagcat ttacgatgtc
     5941 gaccagcgcc cagcggagtc tgtttggata aaaggatcat ggcaagtcct ggaaaaattt
     6001 attcacataa atttag
//
LOCUS       DAJVBX010000231         5925 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.231, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000231 DAJVBX010000000
VERSION     DAJVBX010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 5925)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5925)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5925
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.231"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            68..1522
                     /locus_tag="OPV72_004027"
     CDS             68..1522
                     /locus_tag="OPV72_004027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DASS family sodium-coupled anion symporter"
                     /protein_id="HCR9916193.1"
                     /translation="MAEKKSQGVKWLPFILILVIAAGLWQLTPPSGLSAPAWHSAIIF
                     VATIASIVAKVLPIGAVGIIGITVFALAYAAGDKTASGAITTALSELNSSLIWLIVVA
                     FMIARGFIKTGLGRRIALQMIRLLGKRTLGLAYGLAFADLILSPAMPSNTARCGGVIY
                     PIADSLARSFDSHPEDESRSKIGTFLITCIGNVNDVTAALFMTGYTGNLLAVKLAANA
                     GVTLSWGSWFIAALLPCLVSFLIVPLLVYWLTRPEIKHTPDAPDLARKELAQMGSMAR
                     GEWLMLATVGVLLVLWIFGSSLGVDATTASFVGLSILLLSGVLTWEDVKSEKGAWDTL
                     IWFAALLMMANQLKKLGFTSWFGNLIGDSIGSTMHGTSWIIILLLLNAAYFYTHYFFA
                     SGNAQIAALYAVFLGVGLHLNIPAAPMALMLAFTSSLYCSLTQYTHARGPILFGAGYV
                     PTGIWWRTGFIISLFNQAVFLTVGLAWWKVLGLY"
     gene            1567..2022
                     /locus_tag="OPV72_004028"
     CDS             1567..2022
                     /locus_tag="OPV72_004028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HCR9916194.1"
                     /translation="MTCIFCQIVEGKAPCHKVWEDEHHLAFLSIFPNTDGFTVVIPKK
                     HYPSYAFDLPPQALADLMLATQKVAKKLDKAFPDVSRTGMFFEGFGVDHVHSKLSPMH
                     GTGDLAHWKPIESRQNKFFEQYEGYLSSHDHERADDEKLAALAARIREA"
     gene            complement(2158..4329)
                     /locus_tag="OPV72_004029"
     CDS             complement(2158..4329)
                     /locus_tag="OPV72_004029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgiQ family radical SAM protein"
                     /protein_id="HCR9916195.1"
                     /translation="MSAISLIQPDRDLFSWPQYWAACFGPAPFLPMSREEMDQLGWDS
                     CDIILVTGDAYVDHPSFGMAICGRMLEAQGFRVGIIAQPDWNSKDDFMRLGKPNLFFG
                     VTAGNMDSMINRYTADRKLRHDDAYTPDNVAGKRPDRATLVYTQRCKEAWKDVPVILG
                     GIEASLRRTAHYDYWSDTVRRSVLVDSKADMLMFGNGERPLVEVAHRLAMGETIDQIR
                     DVRNTAIMVKEALPGWSGVDSTRLDTPGKIDPIPHPYGEDLPCADNKPVAPKKQEAKA
                     ITVQPPRPKPWEKTYILLPSFEKVKGDKVLYAHASRILHHETNPGCARALMQKHGDRY
                     VWINPPAIPLSTEEMDSVFALPYQRVPHPAYGNARIPAYEMIRFSINIMRGCFGGCSF
                     CSITEHEGRIIQSRSEDSIINEIEAIRDTVPGFTGVISDLGGPTANMYMLRCKSPRAE
                     QTCRRLSCVYPDICPHMDTDHTPTINLYRRARELKGIKKILIASGVRYDIAVEDPRYI
                     KELASHHVGGYLKIAPEHTEEGPLSKMMKPGMGSYDRFKELFDLYSKQAGKEQYLIPY
                     FISAHPGTRDEDMVNLALWLKRHRFRLDQVQNFYPSPLANSTTMYYTGKNPLGKIGYK
                     SEDVVVPKGDRQRRLHKALLRYHDPANWPLIRQALEAMGKKHLIGGRRECLVPAPTIE
                     EMREARRQNRNTRPALTKHTPVEHQRQGLAANKKRGKGAGR"
     gene            complement(4463..5884)
                     /locus_tag="OPV72_004030"
     CDS             complement(4463..5884)
                     /locus_tag="OPV72_004030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001528005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4459 domain-containing protein"
                     /protein_id="HCR9916196.1"
                     /translation="MKKCFLFIFMCLFIFSANAELKFRPEIENKKIYFQGKVTDYTLN
                     DFIFFGDSREPFYGSENDDYTATADEWLRFYAELPDVRKWQRVVPDDFSMMSGAPWCD
                     IQFFEQENDHSVITGSEHTRCIDFLVTPKRKGLIPMGTKGTLLDYGSYLAFAPQIEHI
                     TLEGRFPEASRTWLQVRSVQTSATSIADLKIMLNEIYARHGYIFRPGGEMDRYFRQQP
                     WYRPRYANVDYLITETEHRNIKLLKELLSPESQRKKALYIQNTTDFCETLKANNIKYV
                     MDNTAEYLTTGADQPINLEKVWQKYRDLMINGGGNCQRDIESYKRYSFLYSEPLGIYY
                     NSTFEFDEKKGKYVLAYVNFDSSCNKEGDTIELEGMMVKREHVIEDNQGQHSDKDLEL
                     KTINLQCVAGAMMDQPDWDRYVQLILPPEKYNYYQRFIGKKITLRGKVMIAESMYHVT
                     PVLLNLLEEQNPIIKVADMPARP"
BASE COUNT         1340 a         1544 c         1536 g         1505 t
ORIGIN      
        1 gtgaatattt attcacattt attatgaatt tacttaatac atataaaata tttatggatg
       61 tgtgattgtg gcggaaaaaa aatctcaggg cgtcaaatgg ctcccattca ttcttattct
      121 ggttatcgcc gccggactgt ggcagctaac gcccccttcc gggttaagcg cgccggcctg
      181 gcattccgcg attatttttg tcgcgacgat cgcctctatc gtggcgaaag tgctgcctat
      241 tggcgcggtc ggtattatcg gcatcaccgt ctttgcgctc gcctatgctg ccggcgacaa
      301 aacggccagc ggcgcgatta ccacggcctt gagcgagctg aacagttcgc tgatctggct
      361 tatcgtcgtc gcctttatga ttgcccgtgg gtttatcaaa accgggctgg gtcggcgtat
      421 cgccctacaa atgatccgtc tgttaggtaa acgaacgctg ggtctggctt atggcctggc
      481 gtttgccgat ctgatcctct cccccgcgat gcccagtaac accgcgcgct gcggcggcgt
      541 gatttacccg atcgccgact cgctggcgcg cagctttgat tcacatccgg aagatgagtc
      601 tcgcagcaaa atcggcacct ttctgatcac ctgtattggc aatgttaacg acgtcaccgc
      661 cgcactgttt atgaccggtt atacgggtaa cctgctggcg gtaaaactgg cggcgaacgc
      721 cggcgttacg ttgagctggg gaagctggtt tattgccgcg ctcttgcctt gcctggtctc
      781 ttttcttatc gtcccgctgc tggtctactg gctgacgcgt ccggaaatta aacatacgcc
      841 ggatgcgccg gatctggcgc gcaaagagct ggcgcaaatg ggcagtatgg cgcgcggcga
      901 gtggctcatg ctggcgaccg tcggtgtgtt gctggtgcta tggatttttg gcagctcgct
      961 cggcgtggat gccacgacgg cctcttttgt cggtctctct attttattac tgagcggcgt
     1021 gctcacctgg gaagacgtta aaagcgaaaa aggcgcctgg gatacgttga tttggtttgc
     1081 cgcgctgctg atgatggcta accagttgaa aaaactagga ttcaccagtt ggtttggcaa
     1141 cctgattggc gacagcatcg gcagtacgat gcatggaacc agttggataa tcatcctgct
     1201 gctgcttaac gcagcctatt tttataccca ctattttttc gccagcggca acgcgcaaat
     1261 cgccgcgctg tatgcggtgt ttctgggtgt cggcctgcat ctgaatatac cggcggcgcc
     1321 gatggcgctc atgctggcgt ttaccagcag cctgtactgc tctcttacac agtataccca
     1381 cgcacgcggc cccattcttt ttggcgccgg ctatgtaccg acgggcatct ggtggcgaac
     1441 gggatttatt atcagcctct ttaaccaggc ggtctttttg acagtcggcc tcgcatggtg
     1501 gaaagtgtta gggttgtatt aaacgcttaa cgcatcgata accccctcgg ttaacggaga
     1561 aatggaatga cctgcatttt ctgtcaaata gttgaaggta aagcaccttg tcataaagtt
     1621 tgggaagatg agcatcacct ggcttttttg tcgatttttc cgaataccga tgggtttacc
     1681 gtagtgatcc cgaaaaaaca ttaccccagc tacgcgttcg atctaccgcc gcaggcgtta
     1741 gcggacctga tgctggcgac ccaaaaagtg gcgaagaaac tggataaggc tttcccggat
     1801 gtcagtcgta cgggaatgtt cttcgaaggt ttcggcgtag accatgtgca tagtaaatta
     1861 agccccatgc acggtactgg cgatttagcc cactggaaac cgattgaatc gcggcagaat
     1921 aaatttttcg aacagtatga aggatacctg tcgtcacacg atcatgaacg ggcagatgat
     1981 gagaaactgg ccgcgctggc ggccagaatt cgtgaggcat aaatacggag cacttctgcc
     2041 ggatggtgtt cggcctgggt cgatctgtgg gcctgataaa cgcagcgcca tcaggcaaaa
     2101 taattgctgg atcgcggctt cgccttatcc agcctgacag gatacctgta aaaccgttta
     2161 acgccccgcg cctttcccgc gcttcttatt agcagcaagc ccctgccgct gatgttccac
     2221 cggcgtatgc ttggtcaacg ccgggcgggt attgcggttc tggcgacgcg cttcgcgcat
     2281 ctcttcaatg gtcggcgcag gcaccagaca ctcacggcga ccgccaatca ggtgcttttt
     2341 gcccatcgct tccagcgcct ggcgaatcag cggccagttc gccggatcgt gataacgcag
     2401 cagcgcctta tgcaggcgac gttgcctgtc tcccttcggc accaccacat cttcactctt
     2461 ataaccaatt ttacccagcg ggtttttgcc ggtgtaatac atggtggtcg aatttgccaa
     2521 cggcgacggg tagaagttct gcacctgatc cagacggaag cggtggcgct tgagccacag
     2581 cgccagattc accatatcct cgtcccgcgt gcccggatgc gcggagataa aatatgggat
     2641 cagatactgc tcttttccgg cctgtttaga gtaaaggtca aataactctt taaagcgatc
     2701 gtagctgccc atacccggct tcatcatttt cgacagcgga ccttcttcag tatgctccgg
     2761 cgcaatcttc agatagccgc ccacatgatg gcttgccagc tctttaatgt agcgaggatc
     2821 ttctacagcg atgtcgtagc gcacgccgga ggcaattaag attttcttaa tgcctttcag
     2881 ctcacgggcg cggcgataaa gattgatcgt cggcgtatgg tcagtatcca tatgcggaca
     2941 gatatccgga tagacgcatg acaggcgacg acaggtctgc tccgcacgcg gcgacttaca
     3001 gcgcagcata tacatgttcg cggtaggacc gcccagatcg gagatcacgc cggtaaaccc
     3061 cggcaccgtg tcgcggatcg cttcgatctc gttgataata gagtcttccg agcggctctg
     3121 aatgatgcgc ccttcatgtt cagtgatcga gcagaaagag cagccgccaa agcagccgcg
     3181 catgatattg atcgaaaagc ggatcatctc ataggccgga atacgggcat tgccgtaagc
     3241 cgggtgcggc acacgctgat acggcagcgc aaacacgcta tccatctctt cagtggagag
     3301 cggtatggcg ggcgggttga tccagacata gcggtcgccg tgtttttgca tcaacgcccg
     3361 cgcgcagcca gggttagttt cgtgatgcag aatacgcgac gcatgggcgt acagcacctt
     3421 gtcgcctttc accttttcaa aggatggcaa caggatatag gttttttccc acggcttcgg
     3481 acgcggcggc tgcacggtaa tcgccttagc ttcttgcttt ttcggcgcga ccggcttgtt
     3541 atccgcgcac ggcagatcct cgccataggg atggggaatt ggatcgattt tacccggcgt
     3601 gtccagacga gtggagtcga cgccgctcca gcctggcagc gcttctttaa ccataatcgc
     3661 agtgttacgc acgtcgcgaa tctgatcgat ggtttcgccc attgccagac ggtgcgccac
     3721 ttccaccagc ggacgctcac cgttgccaaa catcagcatg tcggctttgg aatcgactaa
     3781 cactgaacga cgcacagtat cagaccagta gtcgtaatgc gcggtacggc gcagactggc
     3841 ctcaatgccg ccaaggatca ccgggacatc tttccacgct tctttgcaac gctgggtata
     3901 gaccagcgtg gcgcggtccg ggcgtttgcc cgcgacgtta tccggggtgt aggcgtcatc
     3961 gtggcgcagc ttacggtcag cggtgtaacg gttgatcatc gagtccatgt tgccagcggt
     4021 gacgccgaag aacaggttcg gtttacccag acgcataaag tcgtctttgc tgttccagtc
     4081 cggctgggcg atgatcccca cgcggaagcc ctgcgcttcc agcatacggc cgcaaatcgc
     4141 catgccgaag ctcggatgat cgacatacgc gtcgcccgtc accagaatga tgtcgcagct
     4201 atcccagcca agttgatcca tctcttcacg tgacatcggc aaaaacggcg ccggcccaaa
     4261 acaggcggcc cagtactgcg gccaggagaa aaggtcgcga tccggttgga tcagggagat
     4321 agcgctcata ttgcttccaa aaaattggca aaaaaataat caaaggtcgg ggattataag
     4381 ctggaatgga agagaaatcg aattgattgg tgaggctgca ctctgtagcg gggccgattg
     4441 cctgccccgt cggttatcgt acttatggac gagcaggcat atctgctact ttgataatag
     4501 gattttgttc ttcgagcaaa ttcaacagta ccggcgtgac atgatacatg gattctgcaa
     4561 tcatgacttt ccctcgcagg gtgattttct tccctataaa ccgttgataa taattgtatt
     4621 tttcaggcgg aagaatgagc tggacatagc gatcccagtc aggttggtcc atcatggccc
     4681 ctgccacaca ctgaaggttt attgttttta attcgagatc tttatccgag tgttggcctt
     4741 gattatcttc aatgacgtgc tcgcgtttga ccatcatacc ttccagttca atcgtgtcac
     4801 cctctttgtt gcaggaagaa tcaaagttca cataagcgag aacatatttc cctttctttt
     4861 catcaaactc aaaagtggaa ttgtaataaa tacctaaagg ttcgctgtat aaaaaggagt
     4921 agcgcttata gctctcgata tcgcgttgac agtttccgcc gccattgatc attaagtctc
     4981 tgtatttttg ccatactttt tctaaattga ttggctgatc tgcaccagtc gtaaggtatt
     5041 ctgccgtatt gtccatgaca tatttgatat tattcgcttt cagcgtctca caaaaatcgg
     5101 ttgtgttctg aatatacagc gcctttttac gctgtgactc aggagaaagc agctctttga
     5161 ggagtttgat attacgatgc tctgtctcgg taatgaggta atcaacgttc gcatagcgtg
     5221 ggcgatacca cggctgctgt cggaagtacc gatccatctc accgcccggt ctgaaaatat
     5281 aaccgtgacg agcataaatc tcattaagca taattttaag atcggctatc gaggttgcgc
     5341 tggtttgcac gcttcttacc tgaagccagg tccgcgaggc ttcaggaaat cggccttcca
     5401 gcgtgatgtg ctctatctgc ggtgcaaaag caagatagct gccgtaatcc aacagagttc
     5461 ccttcgtccc catgggaatg agtcctttcc ttttaggcgt cacgagaaaa tcgatacagc
     5521 gcgtatgctc acttccagta atcaccgaat ggtcattctc ttgttcaaaa aactggatgt
     5581 cacaccacgg cgcgccactc atcatagaaa aatcgtcagg aacaacgcgc tgccattttc
     5641 gaacgtcggg caactcagcg taaaacctga gccactcatc tgcagtggcg gtataatcat
     5701 cgttttcgct gccataaaag ggttcgcgac tgtcaccgaa aaagataaag tcattaagcg
     5761 tgtagtctgt gaccttgccc tgaaaataga tttttttatt ttcgatctca gggcggaatt
     5821 ttagttccgc attagctgag aagataaaca ggcacataaa tataaataaa aaacattttt
     5881 tcattattta ccactccctg tatctctctt aacaatcaat gtaat
//
LOCUS       DAJVBX010000232         5613 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.232, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000232 DAJVBX010000000
VERSION     DAJVBX010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 5613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5613
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.232"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(167..1207)
                     /gene="galM"
                     /locus_tag="OPV72_004031"
     CDS             complement(167..1207)
                     /gene="galM"
                     /locus_tag="OPV72_004031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-epimerase"
                     /protein_id="HCR9916197.1"
                     /translation="MLNETPALAPDGQPYRLLTLRNSAGMVVTLMDWGATLLSARIPL
                     SDGSVREALLGCASPEHYPEQTSFLGASIGRYANRIANSRYTFAGETVQLSPSQGENQ
                     LHGGPEGFDKRRWQIVNQNDRQVLFALTSDDGDQGFPGHLCATAQYRLTDDNRISITY
                     RATVDKPCPVNLTNHVYFNLDGDRTDVRQHKLQILADEYLPVDESGIPRQGLKSVANT
                     SFDFRMPKVIASEFLADDDQRKVKSYDHAFLLQTQGDGKKPAARLWSQDGKLQMMVYT
                     TAPALQFYSGNYLAGTPSRGPEPYADWQGLALESELLPDSPNHPEWPQPDCILRPGEE
                     YASLTEYQFIPF"
     gene            complement(1201..2349)
                     /gene="galK"
                     /locus_tag="OPV72_004032"
     CDS             complement(1201..2349)
                     /gene="galK"
                     /locus_tag="OPV72_004032"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001713229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HCR9916198.1"
                     /translation="MNLKEKTRALFAEIFGYPATHTIQAPGRVNLIGEHTDYNDGFVL
                     PCAIDYQTVISCAPRDDRTVRVIAADYDNQVDEFSLDAPIVTHDSQQWSNYVRGVVKH
                     LQQRNNAFGGVDMVISGNVPQGAGLSSSASLEVAVGTVFQQLYHLPLDGAQIALNGQE
                     AENQFVGCNCGIMDQLISALGKKDHALLIDCRTLGAKAVSMPKGVAVVIINSNFKRTL
                     VGSEYNTRREQCETGARFFQQPALRDVSLEAFNAVASELDPVVAKRVRHVLSENARTV
                     EAASALEKGDLQRMGQLMAESHASMRDDFEITVPQIDTLVDIVKATIGDQGGVRMTGG
                     GFGGCVVALIPEDLVPAVQQAVAQQYEAKTGIKETFYVCKPSQGAGQC"
     gene            complement(2352..3398)
                     /gene="galT"
                     /locus_tag="OPV72_004033"
     CDS             complement(2352..3398)
                     /gene="galT"
                     /locus_tag="OPV72_004033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HCR9916199.1"
                     /translation="MTPFNPIDHPHRRYNPLTGQWVLVSPHRAKRPWQGAQETPSQQM
                     LPAHDPDCFLCAGNTRVTGDKNPDYKGTYVFTNDFAALMADTPDAPDSHDPLMRCQSA
                     RGTSRVICFSPDHSKTLPELSLPALTEIVRTWQTQTAELGKTYPWVQVFENKGAAMGC
                     SNPHPHGQVWANSFLPNEAEREDRLQKAYFAEQRPPMLVDYVQRELADGSRTVVETEH
                     WLAVVPYWAAWPFETLLLPKTHVLRITDLSDEQRDSLALALKKLTSRYDNLFQCSFPY
                     SMGWHGAPFNGEENAHWQLHAHFYPPLLRSATVRKFMVGYEMLAETQRDLTAEQAAER
                     LRAVSDIHFRESGV"
     gene            complement(3409..4425)
                     /gene="galE"
                     /locus_tag="OPV72_004034"
     CDS             complement(3409..4425)
                     /gene="galE"
                     /locus_tag="OPV72_004034"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HCR9916200.1"
                     /translation="MRVLVTGGSGYIGSHTCVQLLQNGHDVVILDNLCNSKRSVLPVI
                     ERLGGKHPTFVEGDIRNEALITEILHDHAIDTVIHFAGLKAVGESVAKPLEYYDNNVN
                     GTLRLVSAMRAANVKNLIFSSSATVYGDQPKIPYVESFPTGTPQSPYGKSKLMVEQIL
                     TDLQKAQPEWSIALLRYFNPVGAHPSGDMGEDPQGIPNNLMPYIAQVAVGRRESLAVF
                     GNDYPTEDGTGVRDYIHVMDLADGHVVAMEKLADKSGVHIYNLGAGVGSSVLDVVNAF
                     SKACGKPINYHFAPRRDGDLPAYWADASKADRELNWRVTRTLDEMAQDTWHWQSRHPQ
                     GYSD"
     gene            complement(4648..5556)
                     /locus_tag="OPV72_004035"
     CDS             complement(4648..5556)
                     /locus_tag="OPV72_004035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2167 domain-containing protein"
                     /protein_id="HCR9916201.1"
                     /translation="MAFRFPQIILFLLAAMLFCPSSYAEQKPTAAQEARKTAVEVAVE
                     GMSRAAVAGPTKISLGDKATLNLPEGFTWIPAKEAAVFMREIGNYVDDEYFYGLVFKK
                     EMNGFISIEYDDSGYVKDDDAKNWDADELMDNLRKGTKEANKDRIAKGIEPIEIIGWI
                     EKPTYDATNHRLIWSAAIQDIGTNEPLNEQGVNYNTYLLGREGYFSLNLVTDRGSVDH
                     EIPLAKRILSSVKFNAGQRYADFNESTDKIAEYELAALIGGIAAKKVGLLAMLGIALL
                     KFWKVTAIGVVAVGALARKLLSRKKD"
BASE COUNT         1231 a         1494 c         1535 g         1353 t
ORIGIN      
        1 gtgttggcgg caatgcttac gcataaccat agcgaaaata gtggcgcagt gtaaggttct
       61 tgtgaactca gagttgcgat tttgtcttta agtggtggag gtttgagcag ggcaatggcg
      121 cgtaggcccg ataagcttgc gtcatcgggc atgtagcggc atatcgttag aacggaataa
      181 actgatactc ggtcaggctg gcgtactcct cgccagggcg aaggatacag tcaggctgcg
      241 gccattcagg atgattcggg ctgtccggca gcagttcgct ttccagcgcc agcccttgcc
      301 agtcggcata aggttccggt ccgcgggaag gtgtacccgc cagataattg ccggaataaa
      361 actgtagcgc cggggcggtg gtgtaaacca tcatttgtag ctttccatcc tgtgaccaca
      421 gacgggccgc cggctttttg ccatcaccct gcgtctgtag caggaaagca tgatcgtagc
      481 ttttaacctt gcgctgatcg tcatcggcga gaaactcgct ggcaatgact tttggcatcc
      541 ggaagtcaaa cgaggtattg gctaccgatt ttagcccctg gcgtggaata ccggattcat
      601 ctaccggcag atactcatcc gccagaattt gcagcttatg ttggcgcacg tcggtccgat
      661 cgccgtccag attaaaatag acgtggttgg tcaaattcac cggacagggt ttatcgaccg
      721 tcgcccggta ggtgatggag attctattgt catcggtcag acgatattgc gccgtggcgc
      781 aaagatggcc aggaaagccc tggtcgccgt catcagaggt gagcgcgaat aatacctggc
      841 gatcgttttg gttcacaatt tgccagcggc gcttgtcaaa gccttccggt ccgccgtgta
      901 gctggttctc gccctggctt gggcttaact gtacggtttc gccggcaaac gtatagcggc
      961 tattggcgat acggttcgcg taacggccaa tagaggcgcc gaggaatgac gtctgttcag
     1021 ggtagtgttc cgggctggcg cagcccagca atgcttcccg aacgctgccg tcagacagcg
     1081 gaatacgggc ggaaagaaga gtggctcccc agtccatcag cgttaccacc atccctgcgc
     1141 tgttgcgcag ggttagcagg cggtacggtt gaccatcggg ggccagtgcg ggcgtttcat
     1201 ttagcactgt cctgctcctt gtgacggttt gcatacataa aaggtttctt tgattccggt
     1261 tttcgcttcg tactgttgcg caacggcctg ctgcacagcg ggaaccagat cttccgggat
     1321 cagcgcgaca acacagccgc caaagccgcc gccggtcatg cgcacgccgc cttgatcgcc
     1381 gatggtcgct ttgacaatgt ctaccagcgt gtctatctgc gggacggtaa tttcgaaatc
     1441 atcgcgcatt gaggcatggg actccgccat cagttggccc atacgttgca aatcaccttt
     1501 ctccagcgcg cttgccgctt caacggtgcg cgcattttcg ctcaatacat ggcgaacgcg
     1561 ttttgcgact accgggtcca gttcgctggc gacggcattg aacgcctcaa ggctgacatc
     1621 gcgcagggcc ggctgctgga agaaacgggc gccggtttcg cactgttcac ggcgggtatt
     1681 atactcgctg cccaccagag tgcgcttaaa gttactgttg atgatcacca cggcgacgcc
     1741 tttcggcata gaaaccgctt tggcgccgag cgtacggcaa tcaatcagca acgcatgatc
     1801 ttttttgccg agcgcagaga tgagctgatc cataatgccg cagttacagc cgacaaactg
     1861 gttctcggcc tcttgtccgt tgagcgcaat ttgcgcgccg tccagcggca ggtgataaag
     1921 ctgctggaag acggtgccca ccgccacttc cagcgaagcg gaggagctta acccggcgcc
     1981 ctgcggcaca ttgccgctga tgaccatatc cacgccgcca aacgcgttgt tacgctgttg
     2041 caggtgtttc actacgccgc gcacatagtt agaccactgc tggctatcgt gggtcacgat
     2101 cggcgcatcc agtgaaaatt cgtccacctg attgtcgtaa tcggcggcaa tcacccgtac
     2161 ggtacgatcg tcgcgcggcg cacagctaat tacggtctgg taatcgatag cgcagggcag
     2221 aacaaaacca tcattgtaat cagtgtgctc gccgatcaga ttgacgcggc ctggcgcctg
     2281 aatcgtgtgg gtagcagggt agccgaaaat ttcagcaaac agcgcgcgcg ttttctcttt
     2341 cagattcatt tttatactcc ggattcgcga aaatggatgt cgctgaccgc gcgcaggcgt
     2401 tcagccgctt gttctgcggt taaatcacgc tgggtttccg ccagcatttc atagccgacc
     2461 ataaatttac ggacggtcgc agagcgcagc agcggcggat aaaagtgcgc gtgcaactgc
     2521 cagtgtgcgt tttcttcacc gttaaacggc gcgccgtgcc agcccattga gtaggggaag
     2581 gaacactgaa acaggttgtc ataacgactg gtcagctttt tcaacgccag cgccagagag
     2641 tcgcgctgct cgtcgcttaa atcggtaatg cgcaggacat gcgttttggg taacagtagc
     2701 gtttcgaacg gccacgccgc ccagtaaggc accaccgcca gccagtgttc ggtttcgacc
     2761 acggtgcggc tgccgtccgc cagttctcgc tggacataat ctaccagcat tggcggacgc
     2821 tgttcggcga aataggcttt ttgtaaacga tcttcgcgtt cggcctcatt cggcaggaag
     2881 ctgttggccc agacctgtcc atgcggatgc gggttcgaac agcccatcgc cgcgccttta
     2941 ttttcaaaga cctgcaccca cggataggtt ttgcctaact cggcggtctg cgtttgccag
     3001 gttctgacga tttccgtcag cgcgggcagg ctcaactccg gcagcgtttt actgtgatcg
     3061 ggagaaaagc agatcacgcg gctggtgccg cgcgcgctct gacagcgcat cagcggatcg
     3121 tggctgtccg gcgcatccgg cgtatcggcc atcagcgccg cgaaatcgtt agtaaagacg
     3181 taagtccctt tgtaatcggg atttttatcg ccggtgacac gcgtattgcc cgcacacaag
     3241 aagcagtccg gatcgtgggc cggcagcatt tgctgagacg gcgtttcctg cgccccctgc
     3301 caggggcgtt ttgcgcgatg cggcgaaacc agaacccact ggccggtaag cgggttataa
     3361 cggcgatgcg gatgatcgat gggattaaat ggggtcataa caacgtcctt aatctgagta
     3421 tccctgcgga tggcgtgact gccagtgcca agtgtcctgc gccatttcgt caagcgtgcg
     3481 ggtgacgcgc cagttcagct cgcgatcggc tttgctggca tccgcccaat acgccgggag
     3541 atcgccgtcg cgacgcggcg cgaagtggta attaatgggt ttaccgcagg ctttactaaa
     3601 ggcgttgacc acatccagga cgctactgcc gacacccgcg ccgaggttat aaatatgtac
     3661 gccggatttg tccgccagtt tttccatcgc cacgacgtgc ccgtcggcta agtccataac
     3721 gtgaatgtaa tcgcgtacgc cggtgccatc ctcggtcggg taatcgttgc cgaaaacggc
     3781 gagcgattcg cgacgaccca cggcgacctg ggcgatatag ggcatcaggt tattcggaat
     3841 accttgcgga tcttctccca tgtcgcccga cgggtgcgcg ccgaccggat tgaaataacg
     3901 cagcagcgca atactccact ccggctgggc tttttgcaga tcggtgagga tctgttctac
     3961 catcaattta cttttgccgt aggggctttg cggcgtgccg gtaggaaaac tttcgacgta
     4021 aggaattttg ggctgatcgc cataaacggt ggcagaggag ctaaaaataa ggtttttaac
     4081 gttggccgca cgcatggcgc tgaccaaccg cagcgtaccg ttgacgttgt tgtcatagta
     4141 ctccagcggc ttggcgaccg attcgccgac ggctttcagg ccggcaaagt gaatcacggt
     4201 atcaatcgcg tgatcgtgca gaatttcggt tataagcgct tcgttgcgaa tatcgccttc
     4261 gacaaaggtc gggtgcttac cgcccagacg ttcaataacg ggcagcacgc tgcgcttgct
     4321 gttgcagagg ttatcgagga tgacgacgtc atgaccattt tgcagcaatt gtacgcaggt
     4381 atgacttcca atgtaaccgc taccacctgt aaccaatact ctcataattc gctccgttaa
     4441 gcctatggta tggaataacc atagcataac aaagatgcga aaagtgtgac atgtaataaa
     4501 ttagtggaat cgtttacacg ctggtgattt tacgcattta tatcaattaa atgattacaa
     4561 atcatctgac ttgagaatgc ttctgctttt tatccgaaaa aaaggcgcgt tacgcgcctg
     4621 ggaatgaaac ggacggggca ggagctgtca gtctttttta cgcgagagta gcttcctggc
     4681 gagcgccccg acagcgacga cgccgatggc ggtcactttc cagaatttaa gtaacgcgat
     4741 accgagcata gcaagcagtc ctactttctt ggccgcgata ccgccaatca gcgcggcgag
     4801 ctcatactcc gctattttgt ccgttgattc gttgaagtca gcgtagcgtt gtccagcgtt
     4861 gaacttgacg gaactgagaa ttcttttcgc cagagggatt tcgtggtcaa cagaacctct
     4921 gtcggtcacc agatttaaag aaaaataacc ttcacgtccc agcagatagg tgttgtagtt
     4981 cacgccttgt tcattcagtg gttcgttggt gccgatatcc tggatggcgg cggaccagat
     5041 cagacgatga ttggttgcat cgtaggtagg cttctcgatc cagccaataa tttctatcgg
     5101 ctcaatgcct tttgcaatac gatctttatt cgcttctttt gtgcctttgc gcaggttatc
     5161 cattaattca tcggcatccc agttttttgc atcatcatct tttacataac cagaatcatc
     5221 atattcgata gaaataaatc cattcatttc ctttttaaat acgagaccgt aaaaatattc
     5281 atcgtcaaca tagttaccaa tttcacgcat aaataccgcc gcttcttttg cgggtatcca
     5341 ggtaaatcct tccggtagat taagcgtggc tttatcacct aaactaatct ttgtcggacc
     5401 cgcaacggcg gcgcgactca tgccttcaac agcgacctca acggcggttt tacgcgcttc
     5461 ctgcgcagcg gtcggctttt gctcagcata actgctgggg caaaataaca tggctgccag
     5521 taaaaatagt attatttgtg gaaaacgaaa agccataatg aatcccttgt attcacatac
     5581 gacatcattg tcgaaaattt caggattatt atg
//
LOCUS       DAJVBX010000233         5582 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.233, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000233 DAJVBX010000000
VERSION     DAJVBX010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 5582)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5582)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5582
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.233"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..949)
                     /gene="rssB"
                     /locus_tag="OPV72_004036"
     CDS             complement(<1..949)
                     /gene="rssB"
                     /locus_tag="OPV72_004036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RssB"
                     /protein_id="HCR9916202.1"
                     /translation="MTQPLVGKQILIVEDEPVFRSLLDSWFSSLGATTALAGDGVDAL
                     ELMGRFTPDLMICDIAMPRMNGLKLVENLRNRGDQTPILVISATENMADIAKALRLGV
                     EDVLLKPVKDLNRLRETVFACLYPNMFNSRVEEEERLFRDWDAMVSNPTAAAQLLQEL
                     QPPVQQVISHCRINYRQLVSADQPGLVLDIAPLSDNELAFYCLDVTRAGDNGVLAALL
                     LRALFNGLLQDQLGQQKHRLPELGALLKQVNHLLRQANLPGQFPLFVGYYHSELKNLI
                     LVSAGLNATLNTGAHQVQISSGVPLGTLGNAYLNQLSQRC"
     gene            complement(1040..1945)
                     /gene="rssA"
                     /locus_tag="OPV72_004037"
     CDS             complement(1040..1945)
                     /gene="rssA"
                     /locus_tag="OPV72_004037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase RssA"
                     /protein_id="HCR9916203.1"
                     /translation="MRKMKIGLALGSGAARGWSHIGVIKALKQTGIDIDIVAGCSIGS
                     LVGAAYACNKLSALEQWVCSFRYWDVLRLMDVSWGRGGLLRGKRVFNHYRDIMPVTDF
                     DHCSRRFGAVATNLSTGRELWFTEGDLHLAVRASCSMPGLMSPVEHNGYWLVDGAVVN
                     PVPVSLTRALGADIVIAVDLQHDAHLMQQDLLSVNVGNINEESDDALPWHKRLKERFS
                     SLTSRRGVSSSGAMEIMTTSIQVLENRLKRNRMAGDPPDILIQPFCPQISTLDFHRAH
                     AAIAAGQLTVEKKMDELIPLVRTDV"
     gene            2054..2512
                     /locus_tag="OPV72_004038"
                     /pseudo
     CDS             2054..2512
                     /locus_tag="OPV72_004038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460714.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YchJ family protein"
     gene            2563..3405
                     /gene="purU"
                     /locus_tag="OPV72_004039"
     CDS             2563..3405
                     /gene="purU"
                     /locus_tag="OPV72_004039"
                     /EC_number="3.5.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formyltetrahydrofolate deformylase"
                     /protein_id="HCR9916204.1"
                     /translation="MQSLQRKVLRTICPDQKGLIARITNICYKHELNIVQNNEFVDHR
                     TGRFFMRTELEGIFNDSTLLADLDSALPEGSVRELNPAGRRRVVILVTKEAHCLGDLL
                     MKANYGGLDVEIAAVIGNHETLRSLVERFEIPFELVSHEGLTREEHDTKMADAIDTHQ
                     PDYVVLAKYMRVLTPGFVARFPNKIINIHHSFLPAFIGARPYHQAYERGVKIIGATAH
                     YVNDNLDEGPIIMQDVIHVDHTYTAEDMMRAGRDVEKNVLSRALYQVLAQRVFVYGNR
                     TIIL"
     gene            3576..3717
                     /locus_tag="OPV72_004040"
     ncRNA           3576..3717
                     /ncRNA_class="other"
                     /locus_tag="OPV72_004040"
                     /product="RtT sRNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00391"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="rtT sRNA, processed from tyrT transcript; Derived
                     by automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00391"
     gene            3746..3897
                     /locus_tag="OPV72_004041"
     tRNA            3746..3897
                     /locus_tag="OPV72_004041"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3780..3782,aa:Tyr,seq:gta)
     gene            3948..4079
                     /locus_tag="OPV72_004042"
     ncRNA           3948..4079
                     /ncRNA_class="other"
                     /locus_tag="OPV72_004042"
                     /product="RtT sRNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00391"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="rtT sRNA, processed from tyrT transcript; Derived
                     by automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00391"
     gene            complement(4182..>5582)
                     /locus_tag="OPV72_004043"
     CDS             complement(4182..>5582)
                     /locus_tag="OPV72_004043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEL1-like repeat protein"
                     /protein_id="HCR9916205.1"
                     /translation="QKAEQGDEGAQFSLGSWYAEGRYVKPDYKLAIKWLEKAGKQGSD
                     FSYFILGYHYNYGENFPLSRQKALEWYRKAAELGDSSTQEILGDAYMYGDGFPQNTQL
                     ALEWYRKAASPTNDAGVVRGQGSASSAQFKLGVMYAHGQGVPQDYQQTAILMRKAAEN
                     MYYPAQLYLGVAYFYGEGVPQDYRQAVYWLNEGIPGSYTPGHIPLNALYDKAHPADQV
                     HSQTWYRKTAQRVMAKVQFNFGVWYYNGYHLLKDHNLALEWYRRAAAQGLAEAQDAIG
                     VMFMQGEAVSQDYQQALAWYRKAARQGLPAAQTHLGIMSAFGRGVAQSDRQAIAWYRK
                     AAKQDFAKAQYQLGVAYSMGRGVPENSRNALKWYLKAAEQGFTPAQLALGEIYAHGRQ
                     GVPKDNKQAYIWYYMASIYTEKSKDDCSALIAERNRLKGTLTPDQLSETYAAFDLIRR
                     KINQSKEAKKIARKKY"
BASE COUNT         1377 a         1482 c         1330 g         1393 t
ORIGIN      
        1 cgcaacgctg gcttaattgg ttaaggtagg cgttacccaa tgttcctagc ggcacgccgc
       61 tgctaatttg aacctgatga gcgcccgtat ttaaggtggc gttcaatccg gcggagacga
      121 gaatcaaatt tttgagctca ctgtgatagt agccgacaaa tagcgggaat tgcccaggta
      181 aattggcttg tctgagcaga tgatttacct gttttaatag cgcgcctaac tccggtaaac
      241 ggtgcttttg ttggccgagc tgatcctgca ataagccgtt aaatagcgcc cgcagcaaca
      301 atgcggctaa cacgccgtta tcgcccgccc gggtgacatc caggcaataa aatgccagtt
      361 cgttatcaga tagcggcgca atatccagca ccagtccagg ctgatcggcg gagacgagct
      421 gccggtaatt aatgcggcaa tgagaaatca cctgctgtac cgggggctgc aattcctgca
      481 acaattgcgc tgcggcggtc ggattactca ccattgcatc ccagtcacga aacaggcgtt
      541 cttcttcttc aacccgcgag ttaaacatat tagggtataa gcaagcgaat acggtttccc
      601 gcaagcggtt gagatctttt accggcttca gcaagacatc ttcaacccca aggcgtaacg
      661 ctttggcgat atccgccata ttttctgttg cggaaataac cagaataggc gtctggtctc
      721 cgcgattacg taagttttct accagtttga gaccgttcat tctcggcata gcgatatcac
      781 atatcatgag atcaggggta aaacgcccca tcaactccag ggcatccacc ccgtcgcctg
      841 ccaatgccgt tgtcgctccc aaagaggaaa accacgaatc cagaagcgag cgaaatacag
      901 gctcgtcttc aacaataaga atctgttttc cgaccaatgg ctgcgtcatg ttctctcccc
      961 tgactggctt taatcaatag tggcatggta ttgccgcttg cgcctgtcag aatttgctta
     1021 agtgatcgta aaaggtacat taaacgtcgg tacgcaccaa gggtataagt tcgtccatct
     1081 ttttctctac ggttaactga cccgccgcaa tagcggcatg ggcgcgatga aaatccagcg
     1141 tagagatttg cggacagaat ggttgaatga gaatatcagg cggatcgcca gccatacggt
     1201 tacgtttaag acgattttcc aacacctgga tggaggttgt catgatttcc attgccccag
     1261 acgaactcac gccacggcgt gaagtcaggc tactgaaacg ttcttttaaa cgcttatgcc
     1321 agggcagcgc atcatcgctc tcttcattga tattcccgac atttacagag agcaaatctt
     1381 gctgcatgag gtgggcatca tgttgcaggt ctaccgcaat aacgatatca gcccccagcg
     1441 ccctggttaa cgaaacaggt accggattaa cgactgcgcc atctaccagc cagtaaccgt
     1501 tatgttcaac cggagacatc agccctggca tactgcacga cgcgcgtacg gcaaggtgta
     1561 gatcgccttc agtaaaccat agctctcgtc ccgtgctaag attcgtcgcg accgcgccaa
     1621 aacgtcttga acagtggtca aaatccgtga cgggcataat atcccgatag tgattaaata
     1681 cgcgtttgcc gcgaagcaac cctcctctgc cccaggatac atccatcagg cgtaaaacat
     1741 cccagtagcg gaatgaacat acccactgtt caagcgccga taatttatta caggcatacg
     1801 cggcgccgac cagtgaacct attgagcatc ctgcaacgat atcaatatca atgcctgttt
     1861 gcttgagggc tttgatgacc ccaatatgag accatcctct cgctgcgcca gatcccagcg
     1921 ccagccctat tttcattttt ctcatcgtac ttaacgactt cccctggctt caagacgtag
     1981 caacatcgcc actgctcagt taacataatg ccaccctggc gttcaacgcc gttttatatt
     2041 cagggagatt attgtgtctc agccttgtcc ctgtggtagc gctgacgagt atagcctatg
     2101 ttgtggtcgt attgtgtccg gagaacgagt agcacccgat ccgtcacatc tcatgcgctc
     2161 tcgttactgc gcttttgtga tgaaagacgc agattactta attaagagct ggcatccaac
     2221 ttgcaatgcg gccgcgtttc gtgatgatat catcgccgga tttgccaata ccaggtggct
     2281 cggcctgact atttttgaac atacctagtc agaagcagaa aatacagggt atgttagttt
     2341 tatcgcgcgt ttttccgaac aagggaaaaa cggggcgatt atcgaacgtt ctcgttttat
     2401 caaagaaaac ggtcagtggt attatattga cggtacccgc ccgcagttgg gtcgaaatga
     2461 tccctgcccg tgcggttcag gcaaaaaatt taaaaagtgc tgcggccagt gacgcctgac
     2521 agtattgata cagcaaacac tctcaacagg atttttccgg caatgcaatc actacaacgt
     2581 aaagttctgc gtactatttg tcccgatcaa aaaggcctta tcgcgcggat taccaacatt
     2641 tgctataagc acgagcttaa tattgtgcaa aacaatgaat ttgtggacca tcgcaccgga
     2701 cgctttttta tgcggaccga gctggaaggc atcttcaatg attccactct tctggccgat
     2761 ctggacagcg ccttaccgga aggctctgtt cgtgaactca atcccgccgg acgccgtcgg
     2821 gtagtgattc tggttaccaa agaggcgcat tgtctgggcg acctgctgat gaaagccaac
     2881 tatggcgggc tggatgttga aatcgccgcg gtcattggca accatgaaac gttacgctcg
     2941 ctggttgaac gttttgagat ccctttcgaa ctggtcagcc atgagggatt aacgcgtgaa
     3001 gagcatgaca cgaagatggc ggacgccatt gatacccatc aaccggacta tgtagtgctg
     3061 gccaagtata tgcgtgtttt gacgccaggt tttgtggcgc gcttcccgaa caaaattatc
     3121 aatatccacc actcattcct gccggcgttt atcggcgcgc gtccttatca tcaggcctat
     3181 gagcgcggcg tgaaaatcat cggcgctacc gcgcactatg tgaatgataa tctagatgaa
     3241 ggcccaatca ttatgcagga cgtgattcac gtcgatcaca cctacaccgc agaagatatg
     3301 atgcgtgccg ggcgcgacgt tgagaaaaac gtattaagcc gcgcgctgta tcaggttctg
     3361 gcgcagcggg tctttgttta cggcaatcgg acgattattc tttaatcgtc agtaatatga
     3421 attgattagc tttaatccgt tacggatgaa aagtacgcaa acagttcatt tcaggcaaag
     3481 gaatgcttta cagcgacgtg tcatttgata tgatgcgccc cgcttcccga aaggaagcgg
     3541 gccagtatta agcattaccc cgtggtgggg ttcccgagcg atcataaggg agctgactgc
     3601 aaatctgccg tcatcgactt caaggttcga ctcgagcaat agtgagagaa cgttgccgca
     3661 ggcaacggcc cgaagggtga ggagctttag ctccgaataa tccttcccgc tatagaatgc
     3721 aagcagcata atgaatttat cccgtggtgg ggttcccgag cggccaaagg gagcagactg
     3781 taaatctgcc gtcatcgact tcgaaggttc gattcgagcg cagcgagaaa gcgttgccgt
     3841 aggcaacgac ccgaagggcg aagcgcgcag cgctgagtca tccttccccc accaccatca
     3901 tgatcttcag aaagcatcta accttcattc gacatcggtt tgtcataatt ctacccatgt
     3961 ggggaaggat gagaagcttc gactaaggtt cgattcgagc gaaagcgaga gaacgttgcc
     4021 gcaggcaacg acccgaaggg cgaaacgcgc agcgctgagt catccttccc ccaccaccat
     4081 tacttcataa ggcaccaatt tcaaatcaat cagcactgcc ccgtatcctt accccacagg
     4141 cagacttcac accatggcgc catagcttat tggctatctt atcaatactt cttcctggca
     4201 atctttttcg cctcctttga ctggttgatt tttcgcctga tgagatcaaa ggcggcatat
     4261 gtctcgctaa gttgatctgg ggtaagcgtt cccttgagtc ggtttctttc ggcaatgagc
     4321 gctgaacaat catccttaga tttttccgta tatatacttg ccatgtaata ccaaatatag
     4381 gcctgcttat tatctttagg caccccctgg cgcccatgag cataaatttc cccaagcgct
     4441 aattgtgccg gagtaaaccc ctgctctgcc gctttaaggt accacttcag cgcattccgg
     4501 ctattttcag gcacgcctct tcccatgcta tatgctacgc caagctgata ttgcgctttc
     4561 gcaaaatcct gttttgctgc ttttcgatac catgcgatag cctgtctgtc gctttgcgcg
     4621 acgccgcgac caaaagcaga catgatgccc agatgcgttt gcgcagcagg cagtccctgg
     4681 cgtgcggctt tgcgatacca cgccagcgcc tgttggtagt cctgagaaac ggcctcgccc
     4741 tgcataaaca tcacgccgat cgcatcctgc gcctcggcca atccctgcgc tgcggctctg
     4801 cgataccact ccagcgccag attgtgatct ttcaataagt gataaccgtt gtaataccat
     4861 acgccaaaat tgaactgtac ctttgccatc acgcgttgcg ctgtttttcg ataccacgtc
     4921 tgagagtgaa cctggtcagc gggatgcgct ttatcataga gcgcattcag cggaatgtgg
     4981 cctggcgtat agctgcctgg tataccttca ttaagccagt aaactgcctg acgataatcc
     5041 tgaggcacgc cttcaccata aaaataggca acaccgagat aaagttgcgc ggggtagtac
     5101 atattttccg ccgctttacg catcaagatc gccgtttgct gataatcctg aggaacgccc
     5161 tgaccgtggg cgtacattac tccaagctta aattgtgctg acgaagctga accctggccg
     5221 cggacaacgc ccgcatcatt ggttggagag gcggcttttc gataccactc cagcgctagc
     5281 tgggtatttt ggggaaaccc atcgccatac atataggcgt caccgaggat ttcttgcgta
     5341 ctactatccc ctagttctgc cgccttgcga taccactcca gcgctttttg ccgactaagt
     5401 ggaaaatttt caccatagtt gtaatgatag ccaaggatga aataggaaaa atcagaacct
     5461 tgtttacccg ctttctccag ccattttatg gctagtttat aatcaggctt aacgtatcgc
     5521 ccctccgcat accagcttcc aagcgagaac tgcgcgcctt catctccttg ttccgctttt
     5581 tg
//
LOCUS       DAJVBX010000234         5491 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.234, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000234 DAJVBX010000000
VERSION     DAJVBX010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 5491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5491
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.234"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(86..184)
                     /locus_tag="OPV72_004044"
     CDS             complement(86..184)
                     /locus_tag="OPV72_004044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family small membrane protein"
                     /protein_id="HCR9916206.1"
                     /translation="MRVGVLFPVVIFITAILFLAWFFIGGYAAPGA"
     gene            380..631
                     /locus_tag="OPV72_004045"
     CDS             380..631
                     /locus_tag="OPV72_004045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF333 domain-containing protein"
                     /protein_id="HCR9916207.1"
                     /translation="MKFTWIALPGVLLLSACSSSQPNAPRPPRIGMPNPAAVYCEQQG
                     GTLMPVQTPQGVRSDCKLPNGEIIDEWALWRREHPDTKK"
     gene            700..1011
                     /locus_tag="OPV72_004046"
     CDS             700..1011
                     /locus_tag="OPV72_004046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916208.1"
                     /translation="MFQLKPGALAIVIGAKTPAGRRNIGKSVELFCLCQPGDEFINPV
                     NGHVTLLPKEAPRALWLVTGDVASADGQHGFAWVRAEHLMPLSPDRQPGQAAARQSQL
                     S"
     gene            complement(997..1344)
                     /locus_tag="OPV72_004047"
     CDS             complement(997..1344)
                     /locus_tag="OPV72_004047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HCR9916209.1"
                     /translation="MRIQCKRVYFPAEKDDGYRVLVDRLWPRGIKKAALVYDEWNKAI
                     TPSTELRKAFHSELIDFNHFAQQYRAELAQQHQEGKRLADIARHQPLTLLYAAKDTRQ
                     NHAIVLAEWLREL"
     gene            complement(1463..2647)
                     /locus_tag="OPV72_004048"
     CDS             complement(1463..2647)
                     /locus_tag="OPV72_004048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HCR9916210.1"
                     /translation="MTTALSPRGKQGALLIAGILMIATTLRVTFTGAAPLLETIRTDY
                     GLSTAQTGLLTTLPLLAFALISPLAAGIARRFGMERSLFAAMLLICAGIALRSLPSAA
                     LLFAGTAIIGCGIALGNVLLPGLIKRDFSQHVARLTGAYSLTMGAAAALGSALVVPLA
                     LHGFGWRSALLMLMLFPLLAFLIWLPQWRTTRSANLSSSRALHERGIWRSPLAWQVTL
                     FLGLNSLIYYVIIGWLPTILISHGYSEAQAGSLHGLLQLATAAPGLAIPLILHRFNVQ
                     RWIAALVSLLCALGAAGLWFVLGQAIIWTLLFGFGSGATMILGLTFIGLRASSAHQAA
                     ALSGMAQSVGYLLAACGPPVMGKLHDASGSWYLPLSGVTVLAIIMAIFGLYAGRDREI
                     AS"
     gene            2748..3542
                     /locus_tag="OPV72_004049"
     CDS             2748..3542
                     /locus_tag="OPV72_004049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCR9916211.1"
                     /translation="MIGLRLDGYDPDLHHDAAVAFCIRARDDELFSPRHQHRKGQLIL
                     ALHGAITCEVENAMWMVPPQYAVWLPGSLPHSNHVTAGAELCFLFIEPAAVVMPERCC
                     TLKISPLCRELILSLARRTDSERAQMPTQRLIQVLFDELPQQPQEQLQLPVSGHPKIR
                     QMVETMAQEHARWNTLGQWASVFAMSERNLARLVVKETGLSFRRWRHQLQLILALQAL
                     IAGRNVQQTAQMLGYDSTTAFITMFKKGLGQTPGQYLTGELLLSHN"
     gene            complement(3522..3968)
                     /locus_tag="OPV72_004050"
     CDS             complement(3522..3968)
                     /locus_tag="OPV72_004050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460246.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HCR9916212.1"
                     /translation="MFDVTLLILLGLAALGFISHNTTVAVSILVLIIVRVTPLNTFFP
                     WIEKQGLTVGIIILTIGVMAPIASGTLPPSTLIHSFVNWKSLVAIAVGVFVSWLGGRG
                     ITLMGNQPQLVAGLLVGTVLGVALFRGVPVGPLIAAGLVSLIVGKQ"
     gene            4174..4275
                     /locus_tag="OPV72_004051"
     CDS             4174..4275
                     /locus_tag="OPV72_004051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916213.1"
                     /translation="MYDPPFLEALMITASFFAIFIIIVVSVLLLEGD"
     gene            complement(4272..4790)
                     /locus_tag="OPV72_004052"
     CDS             complement(4272..4790)
                     /locus_tag="OPV72_004052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HCR9916214.1"
                     /translation="MAEVAKGVATHQRLVALLTQENARYRVVSHEAVGKCEAVSEIRG
                     TALGQGAKALVCKVKGNGVNQHVLAILAADQQADLSQLASHLGGLRASLASPAEVDML
                     TGCVFGAIPPFSFHPNLKLVADPLLFERFDEIAFNAGLLEKSVIMNTQDYLRIARPEL
                     AVFRRFQSSPTA"
     gene            complement(4840..>5491)
                     /locus_tag="OPV72_004053"
     CDS             complement(4840..>5491)
                     /locus_tag="OPV72_004053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HCR9916215.1"
                     /translation="NLFQYVNYNHDIPGGLRVSLSLDLTYFLVSSWKALAFYLLATAL
                     LLNMVRMHFRLYRNVTRENISDAMTGLYNRKILTPVLEQRLQRLVNTGTPVTFVAIDC
                     DRLKLINDTLGHQEGDRIITLLAKAIKTSIRKSDYAIRLGGDEFCIILVDYAADLAIH
                     LPERIIRNLQIIAPDKTVHFSAGIYNMQPNDTINDAYQASDAQLYLNKQQKQHRSS"
BASE COUNT         1379 a         1431 c         1469 g         1212 t
ORIGIN      
        1 aaatgaattt accaccagcc cagttcggta cccgccaccg caattagcgc gatgcccatc
       61 aacaccatcg ttgttttcct catggttatg ctcccggtgc ggcgtaaccg ccaataaaaa
      121 accatgccaa aaataatatt gccgtaatga aaatgacgac agggaagagg acacccactc
      181 tcatgctatt accttcactg ttcagggggc gccagaatag cagggttttc tcagcgacaa
      241 aaggttggtt gctttgtgac agggcgtggc tattgctgac ttaacccggg ataaacaccc
      301 actaaagcgc tgacagaaag tatggaaata gcgtacccgc caggttatcc tggacaaaat
      361 atcgctttaa ggagtcgtta tgaaatttac gtggattgcg ttgccaggcg tattgctgct
      421 gagcgcttgt tcatcgtcgc aacccaacgc ccccaggccg ccgcgtattg ggatgcctaa
      481 tccggcagcc gtctactgtg agcaacaggg cggtacgctg atgccggtgc agaccccaca
      541 aggcgtgcgt tccgattgca aattgcccaa tggcgaaatc attgatgagt gggcattatg
      601 gcgcagagag caccctgata cgaaaaagtg acaacctgcg gtccgacggg atatgattaa
      661 gaacaatctg ataatgagtt tcatgcggcg caagaaaata tgtttcagtt aaagccgggc
      721 gcgttggcaa tagttattgg cgctaagaca cccgccggac ggcggaatat tggtaaatcg
      781 gttgagctat tttgcctgtg ccaacccgga gatgaattca ttaatccggt aaatggacac
      841 gtcaccttac tgccgaaaga agcgcctcgg gcgctgtggc tggttacggg cgacgtagcc
      901 tccgccgatg gtcagcacgg ttttgcctgg gtgcgagcag aacatttgat gccgttgtcc
      961 ccggacagac aaccaggcca ggcggcggca cgacaatcac agctctcgta gccactctgc
     1021 cagcacaatg gcatggttct ggcgagtatc tttagcggcg tatagcaacg ttagcggttg
     1081 gtgtcgggca atatccgcca gacgtttgcc ttcttgatgc tgttgcgcaa gttctgcccg
     1141 gtattgctgc gcgaagtggt taaaatcaat cagttcgcta tgaaaggctt tgcgcaattc
     1201 ggtggagggc gtaatggcct tattccattc atcatagacc agcgctgctt ttttaatgcc
     1261 tcgcggccat agcctgtcaa ccaatacccg ataaccatcg tctttttccg ccgggaaata
     1321 gacgcgctta cactggattc gcatttttcc ctcctgtgat ggtgtcgctt acggtacttt
     1381 tgtcggatag cagtaatgat tttaatggat caggcctgat aaacgaagcg tcatcaggca
     1441 ttcaagtggg tatcaggttt atttatgacg ctatctctcg atcgcgtccg gcgtagaggc
     1501 cgaaaatcgc catgatgata gccagaaccg ttacgcccga tagcggcaga taccagctac
     1561 cgctggcatc atgaagtttt cccatgacgg gcggcccaca tgccgccagt aaatacccga
     1621 ccgactgcgc catgccggaa agcgccgccg cctgatgcgc cgaactggcg cgcaggccga
     1681 taaacgtcag gccgaggatc atcgtcgcgc ctgaaccgaa gccgaacagt agcgtccaga
     1741 tgatcgcctg gcccagcaca aaccaaagcc ccgccgcgcc cagtgcgcac aatagtgaga
     1801 ccagcgcggc aatccagcgt tgaacgttaa agcgatgcaa aataagcgga atagctaacc
     1861 caggcgccgc ggtcgccagt tgcagcaggc catgtagcga tcctgcctgt gcttcgctgt
     1921 aaccgtggct gatgagtatt gttggtaacc agccgataat cacataataa atcagtgagt
     1981 taagcccaag aaacagagta acttgccagg ctaaaggcga acgccagata ccgcgttcat
     2041 gtaatgcccg ggagctactc aggttagctg agcgggtagt gcgccactgc ggcaaccaga
     2101 taagaaacgc caacagcgga aacagcatca gcattaacag cgcgctgcgc cagccaaaac
     2161 cgtgcaacgc cagcggaacc accagcgcag accccaacgc ggcggcggcg cccatcgtca
     2221 atgagtacgc gcccgtcagc ctggcgacat gttgtgaaaa atcgcgctta atcaatcctg
     2281 gtagcagcac attacccagc gctatcccgc acccaataat ggcagttccg gcaaacaaca
     2341 atgcagcgga gggcagggag cggagagcaa tacccgcgca aatcagcagc attgcggcaa
     2401 acagactgcg ttccatccca aaccggcggg caataccggc cgccagcggc gaaatcagtg
     2461 caaacgccag aagcggcaag gttgttagca ggcccgtctg ggcggtggaa agaccgtaat
     2521 ccgtacggat tgtctccagc aacggcgcag cgccggtaaa tgttacgcgt agcgtagtgg
     2581 ctatcatcaa aataccggca atcagtaaag cgccctgttt gccgcgtggt gaaagggctg
     2641 tcgtcatcgt tttctcatct cgtcaggcga ggcgatacct taacagtttt tactgtttgg
     2701 atgaatcaag ctaaaatgac aatttatcgc taaaatcgga caatataatg attggcctga
     2761 gactggacgg ttacgatccc gaccttcacc acgatgccgc tgtggccttt tgtattcgcg
     2821 ccagggatga tgaactgttt agccctcgcc atcagcatcg caagggacag ttgatcctcg
     2881 ctctgcacgg cgcgatcacc tgtgaggtgg aaaatgcgat gtggatggtt ccgccccagt
     2941 atgccgtctg gctccccggc tcgctgccgc acagtaatca tgtgaccgca ggggcggagc
     3001 tgtgcttttt atttattgaa cctgcggcgg tcgtcatgcc ggagcgttgc tgcacgctga
     3061 aaatttcgcc gttatgccgg gagttgattt tgtcgctggc gcgcagaacc gattccgaaa
     3121 gagcgcaaat gccaacgcag cgccttattc aggtgttgtt tgatgaactg ccgcagcagc
     3181 cgcaggaaca attgcaatta ccagtatcgg ggcatccgaa aattcgccaa atggttgaga
     3241 caatggcgca ggagcacgcg cgatggaata cgttagggca gtgggccagc gtattcgcga
     3301 tgagcgagcg taaccttgcc cggctggtcg tcaaagagac gggactcagc tttcgtcgct
     3361 ggcgtcatca attacaatta attctggcgc tacaagcgct gatcgcggga cgtaatgtac
     3421 aacagacggc gcaaatgctg ggttatgatt ctaccacggc attcattacg atgtttaaaa
     3481 aaggcctggg gcagacccca ggccagtatc tgacgggcga gttactgctt tcccacaatt
     3541 aaagagacca gccccgccgc aatcagtggg ccgaccggca cgccgcgaaa cagcgcgacg
     3601 ccaagtaccg taccgaccag cagcccggcg acgagctgcg gttggtttcc catcagcgta
     3661 atgccgcgac cacccagcca ggagacgaaa acgccgacgg caatcgcgac cagcgatttc
     3721 cagttcacaa aagagtggat caatgtggag ggcggtaggg ttccgctggc gatgggggcc
     3781 atcacgccga tggtcagaat gataatcccg acggtgagcc cctgtttttc aatccaggga
     3841 aaaaaggtat tcaacggggt tacgcggaca ataatcagca ccagaattga gacggcgaca
     3901 gtggtgttgt ggctaataaa tcccagagct gccagtccga gcaggatcag cagagtgaca
     3961 tcaaacatta tggtttcctt gccaaaaagt aagcctgact actttacgcc caaacggcaa
     4021 agcgcacagg cctttttaac gattgatgcg gatttcaggc aactgcctga aagacaattt
     4081 ctacgtgaaa aacggcgttg tcattaaatt gacatcaacg ccgcgtattg ctaaccggtg
     4141 aaccgtcatt gttgtcttcc tgaggataca attatgtacg atccaccgtt tcttgaagcg
     4201 ctgatgataa cagcgtcgtt tttcgccatt tttatcatta ttgttgtgtc tgtattgctc
     4261 cttgaagggg actaagccgt tggcgatgac tgaaagcggc ggaagactgc cagttctggt
     4321 cgggcgatgc gcagatagtc ctgtgtattc ataatgactg atttttccag cagaccggca
     4381 ttaaaggcaa tttcatcgaa acgctcaaac aggagcggat cggcgaccag tttcagattg
     4441 gggtgaaaac tgaaaggcgg gatcgcgcca aaaacgcagc cggtcaacat atcgacttcc
     4501 gccgggctgg caagggaagc gcgtaagccg cccagatgtg aagcaagctg agagaggtcg
     4561 gcttgctgat cggccgccag aatagcaaga acgtgctggt tgacgccgtt gcctttgact
     4621 ttacagacca gcgcttttgc gccctggccc agcgcagtac cgcgtatttc agataccgct
     4681 tcgcattttc ctactgcttc atggctcacc acacgatagc gcgcgttctc ctgggttaat
     4741 aaagccacta aacgttggtg tgtagcgaca cccttcgcga cttcagccat ttcggccatt
     4801 tcttcctcct ggtacaatat gaacatttac tgcgaagcac tatgatgaac gatgttgttt
     4861 ttgttgtttg ttcagataga gctgcgcatc ggaagcctgg taggcatcat taatcgtatc
     4921 attgggctgc atattataaa tcccggcgga aaaatggact gtcttatccg gtgcgataat
     4981 ctgcaggtta cgaataatac gctccggcag atggatagcc aaatccgccg cgtaatcaac
     5041 aagaataata cagaattcat cgccgccgag gcgaatggcg taatcgcttt tacgaatcga
     5101 tgttttaatc gctttcgcca acagggttat aattcggtcg ccttcctggt gccccagggt
     5161 atcgttgatc agttttaacc tgtcgcaatc aatagcgaca aatgtcaccg gcgtcccggt
     5221 attgaccagg cgttgcagtc gctgttccag caccggtgtt aatattttac ggttgtaaag
     5281 cccggtcatg gcatcgctaa tattttcgcg tgtgacgttg cgataaagcc gaaagtgcat
     5341 ccgtaccata ttaagcagga gcgctgttgc cagtaagtaa aaggccagcg ctttccagga
     5401 cgagacaagg aaataggtta aatcaagcga caacgaaacg cgcagtccac cagggatatc
     5461 atggttataa ttcacatatt gaaacagatt a
//
LOCUS       DAJVBX010000235         5487 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.235, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000235 DAJVBX010000000
VERSION     DAJVBX010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 5487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5487
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.235"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..793
                     /locus_tag="OPV72_004054"
     CDS             <1..793
                     /locus_tag="OPV72_004054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF1311 domain-containing protein"
                     /protein_id="HCR9916216.1"
                     /translation="VSYAGLFDSTPELKCGNDNAVTAAKEWIYNEALGRLQQDYIKEP
                     STLFFDIPQTQYEQQLRAIPVQFSDVITQNPQPENANLRTCSATVAMSIPQPLFKLMK
                     DLPNTLFYISQGDGQVINNTVTWKQVNYNIQLADNNKDIVVTPVQKTDKLARSIYVMA
                     RMTVSGDSIIKKKNNSLIEIAAKKFESRDRELNQVWNSLPTSARTALKQEQRVWVTKK
                     EQQCGKLSDAKSEDIPAEKRISIYKCQLEMTIARTTYLDGSELPD"
     gene            870..1664
                     /locus_tag="OPV72_004055"
     CDS             870..1664
                     /locus_tag="OPV72_004055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraB/GumN family protein"
                     /protein_id="HCR9916217.1"
                     /translation="MELLNQLKRLCRALRGTPNSWPAIDLSLPGGRHLHLVGSIHMGT
                     RDIAPLPAKLVKKLRQADALVVEADISGNETPFSNLPKCPPLVERLSAGLLNTLEKRV
                     SELGMPLIHFDNQPLWQIAMVLQATQAQRLGLRPDYGIDYQLLQAAREMSLPVQELEG
                     AKHQLELLCDLPDGGMALLDDTLTHWHTNARLLQVMIGWWLEQPPTSIGASLPRTFSQ
                     PLYDVLMVKRNEAWRDALLALPPGRYVVAVGALHLYGEGNLPQILK"
     gene            1865..2344
                     /gene="ybaK"
                     /locus_tag="OPV72_004056"
     CDS             1865..2344
                     /gene="ybaK"
                     /locus_tag="OPV72_004056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006818871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK"
                     /protein_id="HCR9916218.1"
                     /translation="MTPAVKLLEKNKIPFNIHTYDHDPNETNFGDEVVRKLGLNADQV
                     YKTLLVAVNGDMKQLAVAVTPVAGQLDLKKVAKALGAKKVDMADPMVAQRTTGYLVGG
                     ISPLGQKKRLPTLIDAPARTFATIYVSGGKRGLDIELAADDLAAILSAKFADIARRD"
     gene            complement(2461..4112)
                     /locus_tag="OPV72_004057"
                     /pseudo
     CDS             complement(2461..4112)
                     /locus_tag="OPV72_004057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459489.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-sugar
                     hydrolase/5'-nucleotidase"
     gene            4285..>5487
                     /locus_tag="OPV72_004058"
     CDS             4285..>5487
                     /locus_tag="OPV72_004058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR9916219.1"
                     /translation="MAMSEPTQPLAGAPAAAAKARTSFGILGAISLSHLLNDMIQSLI
                     LAIYPLLQAEFSLTFVQIGLITLTFQLASSLLQPVVGYWTDKYPMPWSLPVGMCFTLS
                     GLVLLAMAGSFGGVLLAAALVGTGSSVFHPESSRVARMASGGRHGLAQSIFQVGGNFG
                     SSLGPLLAAVIIAPYGKGNVAWFVLATLLAIVVLAQISRWYAAQHRIAKGKPKAIIAN
                     PLPRNKVVLAVSVLLLLIFSKYFYMASISSYYTFYLMQKFGLSIQNAQLHLFAFLFAV
                     AAGTVIGGPVGDKIGRKYVIWGSILGVAPFTLVLPYATLYWTGILTVIIGFILASAFS
                     AILVYAQELLPGRIGMVSGLFFGFAFGMGGLGAAVLGLIADHTSIYLVYKICAFLPLL
                     GILTIFLPD"
BASE COUNT         1286 a         1465 c         1360 g         1376 t
ORIGIN      
        1 agttagttat gcaggattat ttgattccac tccagagtta aaatgtggca acgataatgc
       61 agtcacggcg gcaaaagagt ggatttacaa tgaagcatta ggtcgtttac agcaagacta
      121 tattaaagag ccctccacgc ttttcttcga tatcccccag actcaatacg agcagcaact
      181 ccgggctatt cctgttcaat tcagtgatgt aatcacgcag aaccctcaac cagaaaatgc
      241 caacctacga acttgctcgg ctaccgtcgc catgagtatt cctcagccat tgtttaaatt
      301 aatgaaagac ttaccaaata ctctattcta tatttcacaa ggggatggac aggtaataaa
      361 caatacggtg acctggaaac aggttaacta caatattcag ctagcagaca acaataaaga
      421 tattgttgtc acccctgtgc agaaaaccga taaattggcg cggtctattt atgtaatggc
      481 aagaatgacg gtatctggtg atagcattat aaagaaaaaa aataactcac tgattgaaat
      541 cgcagcaaag aaatttgaga gtagagatcg cgagcttaat caggtctgga attcgctacc
      601 cacctctgcc cgaacggcat taaaacaaga gcagcgagtc tgggtgacaa aaaaagagca
      661 acagtgcggc aaacttagcg atgcaaaatc cgaggacata cctgctgaaa agcgcatcag
      721 tatttataaa tgccagcttg aaatgaccat cgccagaacg acctatctcg acggcagcga
      781 actacccgac tgatcgttga cgtcccgtca gggcgcattg cgcccttttc tccaacgcgc
      841 tagcatgagc tttttcaaag ggagcgcgta tggagctatt aaatcaactt aaacgtttat
      901 gccgcgcgct gcgtggtacc ccaaatagtt ggcctgctat cgatctctcc ctgcccggcg
      961 gtcgtcatct gcatctggtt ggcagtattc atatggggac gcgcgatata gctcctcttc
     1021 cagcaaagct ggtgaaaaag ctacgccagg ccgacgcgct ggtcgttgaa gcggatattt
     1081 ccggtaacga aacgccattc agcaatctcc ccaaatgccc gccgttggtc gaacgtctca
     1141 gcgccgggct gctaaacaca ctggaaaaac gggtcagcga gttgggtatg ccgctgatcc
     1201 attttgataa tcaaccttta tggcagatag ctatggtgct acaggccacg caggcgcaac
     1261 ggctgggatt gcgcccggac tatggcattg attatcagct attacaggct gcccgcgaaa
     1321 tgtcgctgcc ggtgcaagag ctggaagggg cgaaacacca gctcgaacta ctatgcgatc
     1381 tgcccgatgg cgggatggcg ctgctcgacg acacgctgac gcactggcac accaacgcac
     1441 ggcttttgca ggtgatgatc ggctggtggc ttgaacagcc gccgaccagc atcggcgctt
     1501 cgctccccag aacgtttagc caaccgctgt atgatgtact gatggtgaaa cgcaatgaag
     1561 cctggcgcga cgcgctgctg gcactgccac cgggacgcta cgtggtagcc gtaggggcgc
     1621 tacatctgta cggcgaaggc aacctaccgc aaatattgaa ataaaaaatg gccaatatcg
     1681 ctattggccc gtcaaagagg aatttcatcg ttattattat cccgacgctt tcgcttcgga
     1741 tcttcagatt gtcgctcaaa gttgccgcaa ctgccaagac ctaatgcaca agattatact
     1801 attttttagt ccgctttcgg gcgtatgctg atggcaaatc acgtctgtag taagaaggaa
     1861 cgttatgaca cccgcagtta agttactcga aaagaacaag attccgttta acattcacac
     1921 ctacgatcac gatccgaatg aaactaactt tggcgatgaa gtggtgcgta agctcgggct
     1981 aaacgccgat caggtgtata aaacgctttt ggttgccgtg aatggcgata tgaagcaact
     2041 ggccgtcgcc gtgacgcctg tagccgggca gctggatttg aaaaaagtcg ccaaagctct
     2101 gggcgcgaaa aaggtcgata tggccgaccc gatggtggcg caacgcacca cgggatacct
     2161 ggtcggcggg atcagtccgc tgggacagaa gaaacggctg cctacgctga ttgacgcgcc
     2221 agcccgcacg tttgccacta tttatgtttc cggtggtaaa cgcgggctgg atattgaact
     2281 ggcggctgac gatttggccg ccatcctgag tgctaaattc gctgatatcg cgcgtcggga
     2341 ttaagcctgc gtaaaataca ttgccggata gcggcgcaaa cgccttatcc ggcctacagc
     2401 atacataatc cgtaggcctt aaggctgtgc gccatcaggc agagatggct atcagtaccg
     2461 ctacagccag ttcacctcgc catttggcgt aaacgccgcc gcatccaacg gtgaattctg
     2521 ctgaataaac tctttcagca cttccgcgtc aataaacccg gtattcacgt agcccggttt
     2581 gttatcgatg cgcggataac catcgccgcc cgtggcgttg aaactcagcg tcgccatgcg
     2641 gtaggttttg gccggatcaa caggctcgcc tttgattttc agatcggtga gcttgccctc
     2701 tttggcgaca aagctcacat tggcgaactg tggataggcg ccggagtccg gtttcatctg
     2761 cgctacggcg gtgagataat caaccacctc tttgccgctc atatcggcat acaccacaat
     2821 gttgccgaac ggctgtacct tgagcacgct tttataggta atatctcccg cctcaatcga
     2881 gtcgcgaata ccgccgccgc tcatcacgcc aaaatcggca ccggtgcgcg cgatctgcgc
     2941 agccagaatc acccgtccca tattggtctg gacaaatctg accttactgc gatcgccttc
     3001 aagcaggcca ttcacgctac caattttcac ctccagttgc gctttacctt tattctggaa
     3061 cggcgttaat aacgagagca tttgcggatt ttcggcgatt tccggcgtgt aaagtacacg
     3121 ctcgcttttc ccgttatccc aggtcacttt tttcttgaga tttaccggaa taagctggta
     3181 gttaaccatt ttcatctcgc cgttacggaa ttcgaaatcc gcgtggccca catatttacc
     3241 ccactcatgc gcctgcacgc tccagatgcc attttgctta tccggcgcgc agggcgttcc
     3301 cgttacgtaa ttcacctgtt tttattttcc gacgccatgc ataccgggtc ttgtgagtga
     3361 ccgcccacaa tcatcgccag cgaaccggca ggcagactac gcgccatctc aacgtcgccc
     3421 ggcgcattcg aaccgtgatc gccgttgtca taatgtccca tatgcgtggt cgcgataatc
     3481 acgtccggtt tttcattcat attaagttcc tgaatcacca cctttgcttc ttcagcaggt
     3541 ttacgaaact caatatcggt gaaatattcc gggttgccta ttttcgccgt gtcatcggtg
     3601 gttaagccga ttaccgcgat ttttatatcc tggcgtgtaa aaatagccca cggcttaaac
     3661 agacgctcgc cggtactttt ttgataaata ttggcggaaa gaaagggaaa cttcgcccac
     3721 ttttcctgct ggcgcaatac ggtgagcgga ttatcaaatt catgattacc gacggccata
     3781 gcgtcgtagc caatcagatt catcccgcgg aaatcgggct ccacatcctg gagatcggat
     3841 tccggcactc cggtattaat gtcgccgccg gataacaaca ggacgcttcc cccctcttgc
     3901 gccacctctt tacggatact gtccaccagc gttttttgcg ccgccagacc atattcgcca
     3961 tattcgctgc gccagaagtg accgtggtga tcgttggtat gcaggatagt aattttatag
     4021 gttttatctt tttcgtaagc ctgtgcaggc tgagtcgtca gcgcgaacgc cgccagtaac
     4081 gccagcgcca caccccgttt caaaaatttc atctttctct ccctgactca atatcaaccg
     4141 cagaaattac ctttccttgc aataatagac aaatatgttt tcagaattga gacttccttc
     4201 aaacacattt cacaggtatg ttaggcaagt aataattaca catcctacta tctccaacat
     4261 cgcataaaat ttaagtgact ttctatggcc atgagtgaac caacccagcc gttagccggc
     4321 gcgcccgcag cggccgctaa agcacgtact tcgtttggta ttttgggcgc gatcagtctt
     4381 tcccatctgc tgaacgatat gatccagtcg ctaatcttag ctatttatcc cctgttgcag
     4441 gcggagtttt cgctgacttt cgtccagata ggtttgatca ccctgacgtt ccagctcgcc
     4501 tcatcgctac tgcaaccggt cgtcggctac tggacggata aatatcccat gccgtggtcg
     4561 ctgcctgtcg gcatgtgttt taccctgagc gggctggtac tgctggcaat ggcgggaagt
     4621 tttggcggcg tattgctcgc tgcggcgctg gtgggtaccg gctcgtccgt ttttcacccg
     4681 gaatcgtccc gcgtggcgcg catggcctcc ggcggacgtc atggtctggc gcagtctatc
     4741 ttccaggtcg gcggtaactt cggcagttca ttgggcccgc tgctggccgc cgtgattatc
     4801 gcgccctatg gcaaagggaa tgtcgcctgg tttgtgctgg ccacgctgct ggcgatcgtg
     4861 gtgctggcgc agatcagccg ctggtatgca gcccagcacc ggatagcgaa aggcaagcca
     4921 aaagcgataa tcgctaaccc gctgccgcgc aataaagtcg tgctggcggt cagcgtgtta
     4981 ttgctactca ttttctcgaa atatttctat atggcgagca tcagtagcta ctacaccttt
     5041 tatctgatgc aaaaattcgg attatcaata caaaacgcgc agctccatct gtttgccttc
     5101 ctgtttgcgg tggctgccgg gacggttatc ggcgggccgg tgggcgataa aatcggcaga
     5161 aaatatgtga tttggggctc tattctcggc gtcgcgccgt ttacccttgt tttaccctac
     5221 gccacgctgt actggacggg gattttaacg gtgattatcg gctttattct cgcgtcggcg
     5281 ttttccgcca ttctggtgta tgcccaagag ctgctgccag gacgcatcgg catggtttcc
     5341 ggcctgtttt tcgggtttgc cttcgggatg ggaggcctgg gcgcagcggt gctggggctg
     5401 attgcagacc ataccagtat ctatttagtt tataaaatct gtgcttttct gccgcttctg
     5461 gggatactga ccatattctt acctgat
//
LOCUS       DAJVBX010000236         5395 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.236, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000236 DAJVBX010000000
VERSION     DAJVBX010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 5395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5395
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.236"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(40..2676)
                     /gene="gyrA"
                     /locus_tag="OPV72_004059"
     CDS             complement(40..2676)
                     /gene="gyrA"
                     /locus_tag="OPV72_004059"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit A"
                     /protein_id="HCR9916220.1"
                     /translation="MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPV
                     HRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYML
                     VDGQGNFGSIDGDSAAAMRYTEIRLAKIAHGLMADLEKETVDFVDNYDGTEKIPDVMP
                     TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDNEDISIEGLMEHIPGPDFP
                     TAAIINGRRGIEEAYRTGRGKVYIRARAEVEADAKTGRETIIVHEIPYQVNKARLIEK
                     IAELVKDKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINM
                     VALHHGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDP
                     IIELIRRAPTPAEAKAALISRPWDLGNVAAMLERAGDDAARPEWLEPEFGVRDGQYYL
                     TEQQAQAILDLRLQKLTGLEHEKLLDEYKELLEQIAELLHILGSADRLMEVIREEMEL
                     IRDQFGDERRTEITANSADINIEDLISQENVVVTLSHQGYVKYQPLTDYEAQRRGGKG
                     KSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLP
                     LEANERITAILPVREYEEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNDGDEL
                     IGVDLTSGSDEVMLFSAAGKVVRFKEDAVRAMGRTATGVRGIKLAGDDKVVSLIIPRG
                     EGAILTVTQNGYGKRTAADEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMI
                     TDAGTLVRTRVSEISVVGRNTQGVILIRTAEDENVVGLQRVAEPVDDEELDAIDGSVT
                     EGDEDIAPEAESDDDVADDADE"
     gene            complement(3086..4288)
                     /locus_tag="OPV72_004060"
     CDS             complement(3086..4288)
                     /locus_tag="OPV72_004060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mandelate racemase/muconate lactonizing enzyme
                     family protein"
                     /protein_id="HCR9916221.1"
                     /translation="MKITSIEVFDCELKKRDQTMSSYNPVLIRVNTDSGLSGIGEVGL
                     AYGAGAKAGVGIIRDLASLIVGEDPLNIEKIWEFFFRKTFWGMGGGNVFYAGMSAIDI
                     ALWDIKGKYLGVPVYQLLGGKTNEKLRTYASQLQFGWGDKRQILVTPEEYAEAARAAL
                     DDGYDAIKVDPLEIDRNGDDCVFQNRNRNYSGLLLADQLKMGEARIAAMREAMGDDAD
                     IIVEIHSLLGTNSAIQFAKAIEKYRIFLYEEPSHPLNSDNMQKVSRSTTIPIATGERS
                     YTRWGYRELLEKQSIAVAQPDLCLCGGITEGKKICDYANIYDTTVQVHVCGGPVSTVA
                     ALHMETAIPNFIIHEHHTNAMKASIRELCTHDYQPENGYYVAPEQPGLGQELNDEVVK
                     EYLAYVIK"
     gene            complement(4303..5395)
                     /locus_tag="OPV72_004061"
                     /pseudo
     CDS             complement(4303..5395)
                     /locus_tag="OPV72_004061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461216.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
BASE COUNT         1348 a         1472 c         1220 g         1355 t
ORIGIN      
        1 aaaaagggcc ggatatccgg ccctcgcaca gcaataatat tactcgtcag cgtcatccgc
       61 aacgtcgtca tcgctttccg cttccggggc gatatcctca tccccttccg tcacgctgcc
      121 gtcgatagca tcgagttctt cgtcatctac cggttcagca acgcgttgca gacccactac
      181 gttttcatct tccgccgtgc ggataaggat aacgccctgg gtattacgtc ccaccacgct
      241 gatctcagac actcgggtac gcaccagagt accggcatcc gtgatcatca tgatctggtc
      301 gcaatcgtct acctgtaccg caccgacaac ggaaccgttg cgctcggtca ctttgataga
      361 gataacgccc tgcgtcgcac gagacttggt cgggtactcg tccgctgcgg tacgcttccc
      421 gtagccgttt tgcgttacgg tcagaatagc gccttcgccg cgtgggatga tcagagaaac
      481 tactttatcg tctcccgcca gcttaatacc gcgcacaccg gtcgcggtac gccccatcgc
      541 acggacggcg tcttctttga agcgcaccac tttacccgcg gccgagaaca gcatgacttc
      601 gtcagaacca gaagtcaggt caacgccaat cagctcgtcg ccgtcgttga ggtttaccgc
      661 gataataccg gcggaacgcg gacggctgaa ttcggtcagc gccgttttct tcacggtacc
      721 gctggcggtc gccataaaga cgttgacgcc ttcttcgtac tcacgaaccg gcagaatcgc
      781 ggtgatacgt tcgttggctt ccagcggcag caggttaacg atcggacgac cgcgcgcgcc
      841 acggctggct tccggcaact gatagacctt catccagtac agacggcccc ggctggagaa
      901 gcaaaggatg gtgtcatggg tgttggccac cagcaggcgg tcgataaagt cttcttcttt
      961 aatacgtgct gctgatttgc ctttaccgcc acgacgctgt gcttcgtaat cggttaacgg
     1021 ctgatatttc acatagccct gatgagacaa ggttacgaca acattttcct ggctaatcag
     1081 atcttcgata ttaatatcgg cgctgttggc ggtgatttcg gtacgacgct catcgccgaa
     1141 ctgatcgcga attaactcca tctcttcgcg gatcacttcc atcaggcgat cggcgctgcc
     1201 cagaatgtgc agcagttcag cgatctgctc cagcaactct ttgtattcgt cgagcagttt
     1261 ttcatgctcc aggccggtca gtttctgcaa acgcagatcc agaatcgcct gcgcctgctg
     1321 ttcagtcagg tagtattgac cgtcacgcac gccaaattct ggctccagcc attccggacg
     1381 cgcggcgtcg tcaccggcgc gctccagcat cgcagcaacg ttgcccagat cccacggacg
     1441 cgaaatcagc gccgctttcg cttccgccgg cgtcggcgcg cggcgaatca gttcgataat
     1501 cgggtcgatg ttggccagcg caatcgccag agcttcaagg atatgcgcac gatcacgggc
     1561 tttacgcagt tcaaaaatag tccgacgcgt caccacttca cggcggtggc gcacgaacgc
     1621 tgaaataata tctttcaggt tcatgatctt cggctggccg tgatgcagcg ccaccatgtt
     1681 aataccgaag gaaacctgta gctgggtctg ggagtagaga ttattaagca ccacctcgcc
     1741 caccgcatcg cgtttcactt caatcacgat gcgcatcccg tctttgtcgg attcgtcacg
     1801 cagcgcgctg atgccttcca cgcgtttatc tttcaccagc tcggcgattt tctcgatcag
     1861 gcgcgctttg ttcacctgat agggaatttc atggacgatg atggtttcac ggcccgtttt
     1921 cgcgtcagct tcaacttccg cgcgggcgcg aatgtacact ttgccacgac cggtacggta
     1981 ggcttcttcg ataccacgac gaccgttgat gatcgcggcg gtcgggaagt ccggacccgg
     2041 aatatgttcc atcagccctt caatgctgat gtcttcgttg tcgatatacg ccaggcagcc
     2101 gttaatcact tccgtcaggt tgtgcggcgg gatattcgtc gccataccta ctgcgatacc
     2161 ggaagaaccg ttcaccagca gattcggaat tttggtcggc atgacgtccg gaattttttc
     2221 cgtaccgtca tagttatcca cgaaatccac cgtctctttt tcgagatcgg ccatcagtcc
     2281 gtgggcgatt ttcgccagac ggatctccgt ataacgcatt gccgccgcgg agtcgccgtc
     2341 aatagaaccg aagttaccct gaccatccac cagcatgtaa cgcagcgaga atggctgcgc
     2401 catacgaacg atggtgtcat acactgcgga atcgccgtgg ggatggtatt taccgattac
     2461 gtcaccaacg acacgggcag attttttata ggctttgttc cagtcattgc ccaatacgtt
     2521 catggcgtaa agtacgcgac ggtgtaccgg cttcaggcca tctcggacat ccggcagcgc
     2581 acggccaaca atgacagaca tcgcataatc cagataggag ctcttcagct cttcctcaat
     2641 gttgaccggt gtaatttctc tcgcaaggtc gctcatctaa ccgctatccc tctactgtat
     2701 cccggattca aaggtcgcaa attataacac attcgcccac gtactggtaa acggaatgca
     2761 gccagacaat gctttattcg ggtgccacat gctctcttca tttataagcg tggtctcggc
     2821 gtttatcggc gatcagcttc agaggcgaca cagaggagat ctgggcctgg ccaggaatag
     2881 gctggaaaat caatacctcc cgtgtatacc cgtcatactt caagtttcat gtgcgttggc
     2941 ggcaagttac tcggcccatc cctgggcctc gccccgtcgg ggttagcgca agcgctgttc
     3001 aagacggtta accattttat cctgcaactc gaattattta ggggatatgc cgggaggcat
     3061 aaaccataat cagtatcacc agatgctatt taatcacata ggccaggtat tctttcacta
     3121 cctcatcgtt taattcctga cccaatccgg gctgttccgg cgcgacataa tagccatttt
     3181 ccggctgata atcgtgggta caaagttccc gaatagatgc tttcatcgca ttggtatgat
     3241 gttcatgaat aataaagttg ggaattgccg tttccatatg cagcgcggct accgtggaaa
     3301 caggaccgcc gcaaacatgc acctgtacag tggtgtcata aatattagca tagtcacaga
     3361 ttttctttcc ttcggtaatt ccgccgcaga gacacaaatc aggttgcgct acggcaatag
     3421 actgtttctc cagtaattcc ctgtatcccc atcttgtgta ggaacgctcg ccagtggcga
     3481 ttggaatcgt tgttgaacgg gaaactttct gcatattatc agaatttaat ggatggctcg
     3541 gttcttcata aagaaagata cgatactttt ctatcgcctt cgcaaattga atagctgagt
     3601 ttgtaccgag aagagaatgg atttctacga taatatcagc atcatccccc attgcttcac
     3661 gcatagcggc aattcgcgct tcccccattt ttaattgatc ggccagtaac aatcctgaat
     3721 agttacgatt tctattctga aaaacacagt catcgccatt acgatcgatt tcgagtggat
     3781 ccactttaat cgcatcatat ccatcgtcaa gagccgcacg cgccgcctca gcatattcct
     3841 caggtgtcac taatatctgg cgtttatccc cccaaccaaa ttgtaactga ctagcatagg
     3901 ttcttaattt ttcattagtt ttcccgccaa ggagctgata aacaggtaca cctaaatatt
     3961 tacctttgat atcccaaaga gcaatatcaa tagcgctcat tccggcataa aaaacgttcc
     4021 cgcctcccat tccccaaaaa gtctttctga aaaagaactc ccaaattttt tcgatattta
     4081 atggatcttc acccacaatc aatgacgcca gatctctgat gatccctacg ccagctttag
     4141 cgcctgcgcc ataggccagt cctacttcgc caataccact taatcctgag tcggtattca
     4201 cccggataag tactggatta taggatgaca tcgtttgatc tctttttttt aattcacagt
     4261 caaaaacttc aatagacgta attttcataa tttctccatt tatcaggttc gtgatacaac
     4321 atttgtttgt tggctttttt cttttttcac atcaattttc attaacgcca aaacggctac
     4381 cgcagcgaag caaagtattg cctctacaat aaatattcct gtcgcaccat aatgagtaga
     4441 aacgaatccc agtgacttat taatcaggaa tccgccaaga cttgaacatg agttaataaa
     4501 cgcaatgctg atagccaacc ctgacggcga caataatgca gaaggcagcg cccagtaagg
     4561 tccgtaatag ctgaggatcc caacaccata gaacgttagc cccagcattc tcagcgacat
     4621 tgaggggaca agagcaatca tcagaaaacc acagcctgcc agaaacatgg gtaatgcagc
     4681 atgccatttt cgttcattct ttttatcgga atgccagccc caccagggca tgctgaacat
     4741 agcgaaaata aacggaatac tcatgattaa accaacgtca gtatccgtaa aatcagctga
     4801 aaatcccttc accaaccccg gcaaccagta gtttgccgcc agagcagccg cctgaatcaa
     4861 catgtaggcg aaagaaagct gaagcaaaac tggatttttg attacggaaa gaaaggatga
     4921 gttggtattt ttatttaatg cagctgcggt ttcattgtca gtgcgtaatt tattaactaa
     4981 ggccgatatc tgctgtggcg taagccattt agccttttct ggactgtcag gcagtaaata
     5041 aaatgtcagg atgccaagga atacggtagg gataccttca atagcaaaaa gccagcgcca
     5101 gccttcataa tccggggtat tcaaatgctc gatgatccaa ccagacatcg gtgcagccaa
     5161 taccgatgca acagcaatag ataacatgaa gaaactattg acttttccgc gttcacgagc
     5221 cgggaaccaa catgcaagat aataaaccat gcccgggaaa aagccagctt caaatacccc
     5281 caaaaaaatg cgagccagca aaatatgttg agtatcttta gcaaaaaaaa tcagccctgt
     5341 taccgctccc cagccgataa taatggaact aattcatttt cttgcgccaa gcttt
//
LOCUS       DAJVBX010000237         5360 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.237, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000237 DAJVBX010000000
VERSION     DAJVBX010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 5360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5360
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.237"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            20..730
                     /gene="tcfA"
                     /locus_tag="OPV72_004062"
     CDS             20..730
                     /gene="tcfA"
                     /locus_tag="OPV72_004062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001539136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone TcfA"
                     /protein_id="HCR9916222.1"
                     /translation="MNFKDTLPGVFLCVAMFACGHARANMLVYPMAAEINSSREEATS
                     LFVYSKSDHVQYIRTRIMRIEHPGMPQEKEVPAGNDIETGLVVSPEKFALSPGTKKTI
                     RVISTQAPEREEAWRVYFEAVPELEDDPQAGGKQNSSVSVNLVWGVLLRVSPSDPRPA
                     LVTDGHHLLNTGNTRLSLIRAGNCDTTCHWQNIGKSIYPGGSADIPAGIKSNAFRVEY
                     RTGANSPVISADLTAAGK"
     gene            781..1356
                     /gene="tcfB"
                     /locus_tag="OPV72_004063"
     CDS             781..1356
                     /gene="tcfB"
                     /locus_tag="OPV72_004063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001056553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein TcfB"
                     /protein_id="HCR9916223.1"
                     /translation="MYTECTYITVINNKARLFFMNMKTSFIAAAVALATVYSFSVSAV
                     QKDITVTANIDSTLELLQADGSSLPSTMKLDFMPGKGLVHKSLQTRLYSNDQTKSVNV
                     KLLNAPQLINVLDPTKTIDMEVTLGGRSLTTTNSVLEAKTLFPDGKTGDASALLNLDI
                     GQKAGAALQNLPAGEYSGLVSLVISQAVTAG"
     gene            1465..4152
                     /gene="tcfC"
                     /locus_tag="OPV72_004064"
     CDS             1465..4152
                     /gene="tcfC"
                     /locus_tag="OPV72_004064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000092509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial outer membrane usher protein TcfC"
                     /protein_id="HCR9916224.1"
                     /translation="MSRYFWMYYLLGLCSFTSQATLIPPPGFESLLEGQTEQIEVLLP
                     GHSLGLFPVVVKPDTVQFMSPLMVLESSGLAALPAAERQKALAALSRPLLRNSNLVCG
                     VSEAKDSSECGYVATDKEDVAVIFDENNAQLSLFLNRDWLPDEERRDKRWLTPTPEGV
                     SAFIHRQTLYLSDDLHSRNMTLNGSGALGLGDGRYLGGDWAAIWNQSEHYNNSQAWFD
                     NLFVRQDLGNQYYLQAGRMDQRNLSSATGGDFGFSLLPLSRFDGLRTGTTQAYVNHEV
                     DHNATPVMVQVTRNARIDIYRGSELLGSQFLTPGMHTLDTHSLPPGSYPLALRVYEDG
                     ILRRTETQPFSKGGNSFSAQTQWFIQGGLEDTGDKASHYDGETVMAAGFQTGLRKNIS
                     LTEGISLAHEAWYSETRLNSQHAVLDGTLDLSAGILHGTDSTSGNTEQVTYNDGFSAS
                     LWRNHTESDACSGRHPQSVHASMTCQTSMNASLSVSVGNWYALLGYSTSRTEGRPVYR
                     GYDDNSDKENVFWRQAYIPASHRESAQASATYSLNMAGMNINTHGGVWRTRNDGVNDD
                     GLFMSVSVSYASQPPTMTGSNRYTSAGTDIHSSRNQKTQTSWNVNHVRSWQQDLYREL
                     SVGFSGYNDDSWSGSLGGRMSGRMGELSATISNSHQRNAGSASSLTAGYSSSLALSRN
                     GLFWGGGQDGEPASGMAVNVESEGDEGSSGKVVSVRGSSQPFSLGFGQQSLLLMEGYN
                     ATEVTIEDAGVSSQGMAGVKAGGGSRCYFLTPGHLLVHNISASMSRLYVGRVLDKDGR
                     PLLDAQPLNYPFLSLGPSGRFSLQSEHKESSLWLLSKNRILRCPMSVHKRRDVMQVVG
                     DVRCELSDVDALPQALQISPRVIRLLNVAGLLRHSVQEA"
     gene            4175..5254
                     /gene="tcfD"
                     /locus_tag="OPV72_004065"
     CDS             4175..5254
                     /gene="tcfD"
                     /locus_tag="OPV72_004065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000066477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein TcfD"
                     /protein_id="HCR9916225.1"
                     /translation="MSNKMKWTSMTAHWSAIINFIRKYVYPARIIAILLMAGATLPQV
                     ADAITVDLNYDKNNVAVITPVWSQEWSVANVLGGWVCRSNRNENEGACEETHLVWWYA
                     FGAYSKIRLRFREQISHAEITLILLGSVRDACYTGVINMNAAACQWGRSLKLRIPSEE
                     LAKIPTSGTWKATLVLDYLQWGGDDPLGTSTTDITLNVTDHFAENAAIYFPQFGTATP
                     RVDLNLHRMNASQMSGRANLDMCLYDGGVKARSLQMKIEGSNKSGTGFQVIKSDSADT
                     IDYAVSMNYGGRSIPVTRGVEFSLDNVDKAATRPVVLPGQRQAVRCVPVPLTLTTQPF
                     NIREKRSGEYQGTLTVTMLMGTQTP"
BASE COUNT         1344 a         1210 c         1470 g         1336 t
ORIGIN      
        1 ttatacggta aaatctggta tgaattttaa agatactctt cccggggtgt ttctctgtgt
       61 cgctatgttt gcatgtggtc atgccagggc gaatatgctc gtttatccca tggcggcaga
      121 aattaatagt agccgcgaag aggccacctc gctgttcgtc tattctaaat cagatcatgt
      181 gcaatatatt cgaacaagaa tcatgcgtat tgaacacccc ggtatgccac aggagaagga
      241 ggtaccagca gggaatgata tagagacagg acttgttgtc tccccggaga aatttgctct
      301 ttccccggga acaaaaaaaa caatacgtgt tatcagtact caggcaccgg aaagagagga
      361 agcctggcgg gtatacttcg aggctgttcc tgaactggaa gatgatccac aggcaggcgg
      421 aaagcaaaat tcatccgtaa gtgtgaatct tgtctggggg gtgttgctgc gtgtttctcc
      481 gtcagacccc aggcctgcgc tggtaacgga cggtcaccac ctgctgaata cgggaaacac
      541 acggctttct cttattcggg ctggcaactg cgacaccaca tgccactggc agaatatagg
      601 caaaagtatt tatcccggcg ggagtgctga tattccggcc ggaataaaaa gtaatgcatt
      661 tcgtgtggaa tatcgtacgg gtgcaaattc accggtaatc tctgctgatt taacagcagc
      721 cggaaagtaa aaacacacgg agcgtacgct ataccctaca tttattctca gggggagcgg
      781 atgtataccg agtgtacata tatcactgta ataaacaaca aagcaaggtt attttttatg
      841 aacatgaaaa catcttttat tgccgcagct gtggcattgg ccaccgttta ttctttttct
      901 gtttctgcgg ttcagaagga tattaccgtc actgccaata ttgacagtac acttgaactg
      961 ctgcaggccg atggttcatc cctcccgtcg actatgaagc tggatttcat gccgggtaag
     1021 ggcctggtcc ataaatcact ccagacccgc ctttacagca acgatcagac caagtcggtt
     1081 aatgtaaaac tgttgaatgc tccacaactt atcaacgtcc tggatcccac caaaaccatt
     1141 gatatggaag tgactctggg aggacggtca ctgaccacca ccaattctgt actggaagct
     1201 aaaaccctgt tcccggacgg aaaaactggc gatgcttcag ctctgctgaa cctggatatt
     1261 ggtcagaagg ctggagcagc cttacaaaac ctgcctgccg gtgaatacag cggattggtc
     1321 agtctggtga tttcacaggc tgtcactgcc ggctaataac tggttattag ctcttcatct
     1381 gatccggttt tgggggggca ccgttcgtac ctgaaccgga tccggtattg atcttattat
     1441 tcattgcaat tcaggtctct ttacgtgagt cgttatttct ggatgtatta tttactggga
     1501 ttgtgcagtt ttaccagcca ggcaactctt attccccctc ctggatttga atctctgctg
     1561 gaaggacaga ctgagcaaat tgaagtgttg ctaccagggc attcactggg attatttccg
     1621 gtggtggtta aaccggacac cgtgcagttc atgtccccat tgatggtact tgaaagcagt
     1681 gggcttgccg cgttgccggc cgcagaacgg caaaaagcgc tggctgcact cagccgtccg
     1741 ttgctacgta acagcaatct ggtctgtggt gtctcagaag caaaagacag cagcgagtgt
     1801 ggttacgtgg caacagataa agaggatgtt gcggttattt ttgatgagaa caacgctcag
     1861 ttatctttgt ttcttaaccg ggactggttg ccggatgaag aacgacgtga taaacgctgg
     1921 ctgactccga ccccggaggg tgtcagcgca tttattcacc gccagacgct gtatctgagt
     1981 gatgatctcc acagtcgtaa tatgacactg aatggtagcg gtgccctggg gcttggtgac
     2041 ggtcgttatc tgggaggcga ctgggcggct atctggaatc agtcagaaca ttacaataac
     2101 agtcaggcct ggtttgacaa tctgtttgtc cgtcaggatc tcggcaatca gtattatctc
     2161 caggctggtc ggatggatca gcggaatctg tccagcgcca cgggggggga ttttgggttc
     2221 agtctgcttc ccctgagccg gtttgatgga ttacgaaccg ggaccaccca agcttatgtt
     2281 aaccatgagg tggaccataa tgccactccg gttatggttc aggttacccg aaatgcccgt
     2341 attgatattt atcgtggcag cgagttgctg gggagtcagt tcctgacccc gggaatgcat
     2401 accctggata ctcattctct tccaccggga agctatcctc tggcgttgcg ggtgtatgag
     2461 gatgggattc tgcggcgaac ggagacccag cccttcagta aggggggcaa tagcttcagt
     2521 gcacagaccc agtggtttat tcagggcggg ctggaagata ccggggataa agccagccat
     2581 tatgacggtg agactgtcat ggctgccgga ttccaaactg ggctgcggaa aaatatcagt
     2641 ctgaccgaag gtatctctct ggcacatgag gcctggtaca gtgaaacccg actgaattca
     2701 cagcatgcag tgctggatgg cacgctggac ctttctgccg ggatactgca tgggacagac
     2761 agcacgagcg gtaacactga gcaggtgaca tacaacgacg gattttccgc gagtctgtgg
     2821 cgtaaccata cggaaagtga tgcctgtagt ggtcgtcatc cacagtcagt gcatgccagt
     2881 atgacctgcc agacttcgat gaacgcctcc ctgtcggttt cggtggggaa ctggtatgcc
     2941 ctactgggat acagtaccag caggacagaa ggtcggccgg tttaccgggg atatgatgat
     3001 aacagtgaca aagaaaatgt gttctggcga caggcataca tccctgcctc tcaccgcgaa
     3061 tctgctcagg ctagtgcaac gtacagcctt aatatggctg gcatgaatat taatacccat
     3121 gggggagtat ggcgaacccg aaatgacgga gtgaatgatg atggcttgtt tatgagtgtc
     3181 agtgtgtcat atgcctctca accaccgaca atgactggca gtaataggta tacctcagcc
     3241 gggaccgata ttcacagtag ccggaatcaa aaaacacaga cgtcctggaa tgtgaaccat
     3301 gtgagatcct ggcagcagga tctgtatcgt gaactgtcgg tgggtttctc cggttataac
     3361 gacgacagct ggagcgggag tctcggcgga cgcatgagcg gccgtatggg tgaactgagc
     3421 gccactatca gtaactccca tcaacgtaat gcgggcagcg ccagttcact caccgctggc
     3481 tacagctcgt ctctggcgtt atcccgtaat ggactgttct ggggaggtgg tcaggacggt
     3541 gaaccggcct ctggcatggc ggtgaacgtg gagtcagagg gggacgaggg cagtagcggg
     3601 aaagtagtca gcgttcgtgg cagcagccag ccgttcagtc tcggttttgg tcagcagtcg
     3661 ctgttgctga tggaaggcta taacgccacg gaggtgacca ttgaggatgc aggggttagt
     3721 tcacagggta tggcaggcgt aaaagcggga gggggaagca ggtgttactt cctgacaccc
     3781 gggcatctgc tggttcacaa catcagcgcc agtatgagcc gactgtacgt tggccgcgta
     3841 ctggacaagg atggcagacc gctgctggac gcacagccac tgaactatcc atttttgtcg
     3901 ttgggacctt ccgggcgatt tagcctgcag agcgagcata aagaatccag cctgtggctg
     3961 ctgtctaaaa acaggatcct gcgttgtccg atgtcagtac ataaacgtcg ggatgttatg
     4021 caggtagtgg gtgatgtgcg gtgtgaatta agtgacgtgg atgccctgcc acaggcgttg
     4081 caaatatcgc cgcgggtcat ccgtttgctg aacgtggcag gtttgctgcg ccattccgtt
     4141 caggaagcct gacgtagaga taaaggcgtt aactatgagt aataaaatga agtggacgag
     4201 tatgacagcc cattggtcag caattattaa tttcatccga aaatatgttt atccagcaag
     4261 gataattgcc atcctgctga tggctggcgc tacactgcca caagtcgccg atgcgattac
     4321 cgtcgacctg aattacgaca agaacaatgt agcggtcatc actcctgtct ggtcccaaga
     4381 atggagtgta gcaaatgtgt tggggggatg ggtatgtcgt tcaaacagga atgaaaatga
     4441 gggggcgtgt gaagaaacac atttggtatg gtggtatgct tttggagctt attcaaaaat
     4501 tcgtctgcgt ttcagagaac aaatcagcca tgctgaaatc acgctcatac tgctcggcag
     4561 tgttcgtgat gcctgttata ctggtgtcat caacatgaac gctgctgcat gtcaatgggg
     4621 taggtcgctg aaacttagga taccttcaga agagcttgcg aagataccta caagcggaac
     4681 atggaaagca acgttagtcc tggattattt acaatggggc ggagacgatc ctttaggcac
     4741 atcaactaca gatatcacgc tgaatgtaac agaccacttt gctgaaaatg cggctattta
     4801 ctttccgcaa tttggtacag caacgccccg ggtggacctg aatcttcacc ggatgaatgc
     4861 ctcacaaatg tcgggcaggg ctaatctgga tatgtgtctg tatgacggag gtgtgaaagc
     4921 ccgttcatta cagatgaaga tagaaggaag caataagtca ggtacgggat ttcaggttat
     4981 aaagagcgat tctgctgata cgattgatta tgcggtcagt atgaattatg ggggacgaag
     5041 tattcctgtc acccgtggcg tggagttcag tctggataac gtggataaag cagcaacgcg
     5101 tccggtggta cttcccgggc aacggcaggc ggtacgttgt gtgccagtgc cccttaccct
     5161 gacaacacaa ccctttaaca tcagagagaa gcgttctggt gagtatcagg gaacgctgac
     5221 agtgacaatg ctgatgggaa cacaaacccc ctgacagtaa ttatttattt tattgatatc
     5281 tttcttatat ggttttttaa atcagagttc tctttatata cttgttttat ttaataaaga
     5341 gaatctattc acttatgaaa
//
LOCUS       DAJVBX010000238         5357 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.238, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000238 DAJVBX010000000
VERSION     DAJVBX010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 5357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5357
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.238"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(11..778)
                     /locus_tag="OPV72_004066"
     CDS             complement(11..778)
                     /locus_tag="OPV72_004066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2094 domain-containing protein"
                     /protein_id="HCR9916226.1"
                     /translation="MRRPAVVSAPAMFGRLPDQRDYVRWRVGAEEGRIWQDWLNRQTW
                     VGSGRHIVLPEGQTTDEERDGWMHLSPRGEHDMPAPEHHPLPWSFVMSPGFLPMGGTT
                     DWLTGVLMASRDSVGRPWPLVIYQRCGREWLDESLQETQGWLYWLARLAAQHITPDTM
                     RRGRLTEQVDQLWAMWQPGPWWAQWLRGLRRTSQRSWELTGLPDEAPVVELPGVRYLP
                     WPGWPGKTLGQATPGQGWFWQQNSEGRYVDALRLAEK"
     gene            complement(778..4639)
                     /gene="tssM"
                     /locus_tag="OPV72_004067"
                     /pseudo
     CDS             complement(778..4639)
                     /gene="tssM"
                     /locus_tag="OPV72_004067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459283.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system membrane subunit TssM"
     gene            complement(4876..5352)
                     /locus_tag="OPV72_004068"
     CDS             complement(4876..5352)
                     /locus_tag="OPV72_004068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012126156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916227.1"
                     /translation="MLKSNHNSSSFESPDFVDSKDFYAGIGYDQGKLGAQFENTCAAR
                     MSVALIKSGVKFKGRLLPIKEGKWKGRSIETGAKNLADILSQATVFGKPAVWRDPTKF
                     QTELGNKKGVVFFWKIDGYNGGSGSHIDLIEPTSAGAVCHSHCYFSCKQIWFWELR"
BASE COUNT         1089 a         1775 c         1427 g         1066 t
ORIGIN      
        1 accatgttca ttatttctcc gccagtcgca gcgcatccac ataccgccct tcactgttct
       61 gctgccagaa ccagccttgc cccggtgttg cctgccccag cgtcttgccc ggccagcccg
      121 gccacggcag ataacgcacg cccggcagtt ctactaccgg tgcttcatcc ggcagcccgg
      181 tcagttccca gctgcgctgc gatgtacgtc gtaacccgcg cagccactgc gcccaccacg
      241 gccccggctg ccacatcgcc catagctggt ccacctgctc cgtcagccgc ccgcgccgca
      301 tcgtgtccgg cgtgatatgc tgcgccgcca gcctcgccag ccagtacagc cagccctgcg
      361 tctcctgcaa actctcgtcc agccactccc gaccgcagcg ctggtaaatc accagcggcc
      421 acgggcgtcc cacgctatcc cgtgacgcca tcagcactcc ggtcagccag tcagtcgtcc
      481 cacccatcgg caaaaatccc ggcgacatca caaagctcca cggcagcgga tggtgttccg
      541 gcgcgggcat atcatgttcg ccacgcggcg acaggtgcat ccagccgtca cgctcttcat
      601 cggtcgtctg gccttccggc aacacgatat gccgcccgct gcccacccat gtctggcggt
      661 tcagccagtc ctgccatatt cgtccctctt cagcgcccac ccgccagcgc acatagtcgc
      721 gctggtccgg caacctgccg aacatcgccg gggctgatac caccgctggc cggcgcatta
      781 caacgccctc gccggacaac tgaagttctg caacagctcc cggctgaccg ggttaaaatc
      841 ccgcccggca gtgatttcca gcaccacccg gcgaccgtca aaatcatatt ccaccaattg
      901 gcgcccccgc accgccgttt cctgtacctt tccggcgtcc agcagatgaa acagcgccca
      961 cggcccgccg gtcagtagcg ttgaggtgtc ctggcgaata cgcgggctgg cggtgatttc
     1021 cgccatcgag ccgttgcgcg gtcccggcca cgtcactttc aggggccggt ccggaccatg
     1081 ggcgtagcgc agcacctgac catcgatatc aatcaccagt tccgtgatgg ccgggtccat
     1141 atccaccacg ctaatctgca tcgaccagga aaattttttc ctgccctcgc tgttaaaaaa
     1201 cacgctgcgg atctgcttcg cctgctgaaa cggcgttaaa tccggcccct gcaatgtcat
     1261 gttgccttcg gtcggtttgt agcgccacgg gtcgctggcg gtgtccgcca gcggagccag
     1321 ttgtttgctc cagaaagcat ccagtacgcc gccgctggcg aagatgcggt taaagtcctc
     1381 ggcgctgacc tcctgcggac tatcggcgaa cggatagcgc ccgtcgatgg cgtcacggca
     1441 gtcgtcgccc atcatcgcct ccatctgggt gttgagcaca tcgccggtcc cggcgttgat
     1501 tttgcgcgtt ccctgcttcg tcagatccag caggatgttt ttcagcggcg caggcagttt
     1561 cgccgcctcc agttgcaact tgtctgcggc agtaatgcgc gctggcaacg tccccgccgc
     1621 cagcgcgctg tcagcaatgg ccagttgggt gtaatactcg ttgagcatgg tcagcagcga
     1681 agcgatctgc atcgtcccac cgccgctctg tccgccgtcc gtccgcccgg caatgacctc
     1741 gcgcagcgcg gcgaaacggt catccaccag cgttttttcc agccgctctt ccgggtgaat
     1801 atcctggaac agttttgccg tctgtaccac tttccccgcg ttaccggacg cgcgctgcgc
     1861 cagttgtttc tgtctggcct gcgggtccgg cggcggcacc agcgtggtct gctccaccac
     1921 cgcttttccc agccgcatca gcggtgagtc cggcgacgcc agggtgcgca gcacctgtaa
     1981 atcataggcc aggccggaac tgccctcttc cccggcactg ttgatactat ggatactgtc
     2041 cagaaaatcc tgccagcggc gggcatattc cgtcaggtac aaacggcgga cttcgcgggc
     2101 gacagactgc tcctgccccg gtatctggct gcgcaggctg tcagtcagct tttttggcgt
     2161 actctcccgg cccatcaccc agccatcgtt cgccgtcgcc acaaattccg gtaatcgttt
     2221 gtcgaacagc tcccggtaac cttcacgggt aaaaataccc ggcacgcccc gatccagcgg
     2281 cgcgccgttg ctacgcacaa acaccgttcc cgcatccgcg ccgacggcgc gtaccagcgt
     2341 gaactcctgc ggcgcttcgc tctccatcac cgccagcgcc cgcgcataga tacgctcggt
     2401 actggtgtga ccgtcgagga atgcccgcgc ctggcggatc agcgcctcat ctttctcata
     2461 cggtgaatgc accacccggc tgccgtcaaa cagcgcttcg atatgcgtca gcacggcggc
     2521 gcgcccgcca aacccggcca cgctgtcgct gttccccaga tcgttaatca cccacgactg
     2581 gatctccgcc gcgttgtatt tatcttcgtg atctttatcc agattcagta gcagatagat
     2641 gcgcagggca tcatacgcag ctttactgtc ctgacgggca atggcgtctg ccagcacata
     2701 ctccatccgt ttcaccagcg gcggcagcag cagttgatcc agcagacggt tgtacagcga
     2761 cgccacgctg tcggttaccg gcggtacgct gtacaggccg tagcgccagg tcagcggcgg
     2821 cgcgtccggg tccagtcggc caggcggaca gttcccttgc gctgtccagc agtgccggga
     2881 cgggagccat cgccggttta ccggtgtagg ctttcacatc accgtccagc cgggtcgcgc
     2941 gggcgctgat ttcattcaga tagtcgccgt tggtctgctg gctggtctgc atcccctgcc
     3001 acaacaggaa tgccagcacc agtaccagca ggtgcccgcc gaggcgcagc aggcggtaac
     3061 gccaggccca ctggaggttt ggctccacca ggtgcgcttc acggaaaata aactgtgtca
     3121 gcaggtcatg cagaaagtag ctgcggttgc cgtccggcag agcgtgtggg agagaggcgg
     3181 atgattcgcc acgggtggtt tttatcgccc ggacaaagcg ctgccagata ctcaactggt
     3241 cggccacggc gtcggcctgc gcctgcgcgg cgctggtgaa aaacaccccg cgcagcgtgt
     3301 tattcagttg cgtggcatcg aattttgaat cgaggaagat ctgttcaata gcctccagca
     3361 acggctcgcc gagggcggcg aactcacgcg ggaaggtata cagccgctgg cggcttttaa
     3421 ggtcgtactc ttcctgtaac cgggtatcca gtccctgatc cagccgcagc gtcaggcgcg
     3481 ccagctcctg cgcgcaggcg gcatgcagcg cctgcgggtc gcccgttttt cgcctgcggc
     3541 tgtacggcaa cgtaaagccc cagatttgtg cgcgaagatg gctggtcagc gtacgaaaat
     3601 actcgctgaa ccccggcaac aaatccattt tagtgaccac cagatagacc ggaaagcgaa
     3661 tccccagggt ctcgcgcagt tctgccagtc gcgcccgcag agcggcgcag gccgccaggc
     3721 gttccgccgg tggctgtgcg gttaaatccg ctacgtttag cgtcaggatc acgccgttaa
     3781 gcggcgcgcc ggggcgatgt ttacgcagca gaccgagaaa gccctgccac tctccggcgt
     3841 tgcgctgcgc ggcgctcgct tcgccgccgt catcgtggcg cgcgtagcgt ccagcggtat
     3901 caatcaacac cgcttcgttg gtaaaccacc agtcgcagtg tagcgtgccg ccacccggca
     3961 ctgtcaggat gcgcgaggtc tgctccattt gctccgccag cgggaactgc aatccggtgt
     4021 tcagcagggc cgtggttttg ccgtcgccgg gactgccgac caccatgaac cacggcagct
     4081 catacagaaa gcgttttccc tcgaagattt tacgccagcc aggcatatcc acccgcaact
     4141 gccgcagctg ccggatggcc tgcgtgacaa tatggttgac ggtgcgcagg tcggctttga
     4201 tctcgcctgc caccggtacc tcttccccgc gcggatgcag gaagcgacgc agcagttgtt
     4261 catccatacg cagcgcacgc cacagccggt acaggccgta cagcgcgtac atcagcagga
     4321 tgaaaccaat cagggtcagg cggacccaca gcggcgcaaa cggatggaca tcgcccaggg
     4381 ccagcagcgg tgtgacgaag ccaatcgcca ggcacaggac actgatgccg atgatactca
     4441 tcgaccagtt gaccagccac agtaccagca acatcagcaa cagggcaatg gtcaccaccc
     4501 ggctgcccac ggaggccagc gggcgcaggg tatcaaatga caccagcggc ccgacaaacc
     4561 agaccagcag cgccagaacc agaacgccca caatcgccag cgcgcgccgg gaaaaaagca
     4621 gactgagaaa tttttgcatt atatttcgac tcgccaccca ataatcagta acagcaaagc
     4681 gctgagacca gaaaacaatc tcccgttacc gtaattaatt taaaaaaaat atagaaagct
     4741 cttgaaaaat aataaatccg gaagtcaaaa atacttcacg gaccctgaac gtgtgttttc
     4801 gtctctcaac ccttcagaat tccggcatta ttacattcca tttcactcaa atcacacgaa
     4861 cggaatttca gaattttagc gtaattccca gaaccaaatt tgcttacagg aaaaataaca
     4921 gtgtgaatga catactgccc cggcactggt cggctcaatc agatcgatat gactaccact
     4981 cccaccatta tatccatcaa ttttccagaa gaagaccaca ccttttttat tacccagttc
     5041 tgtctgaaat ttagtcggat cacgccagac cgcaggttta ccgaaaacag ttgcctgcga
     5101 aagtatatct gccagatttt tagcgcctgt ttcaatgctc cggcccttcc acttgccctc
     5161 ttttatcggg agaagacggc ctttaaactt cacacctgat ttaattaatg ccacgctcat
     5221 acgggccgca caggtatttt caaactgagc accaagtttc ccctggtcat aaccaatgcc
     5281 tgcatagaaa tctttcgaat caacaaaatc aggactttca aaagatgatg aattatgatt
     5341 agactttagc actgaga
//
LOCUS       DAJVBX010000239         5350 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.239, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000239 DAJVBX010000000
VERSION     DAJVBX010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 5350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5350
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.239"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(32..1315)
                     /gene="aroA"
                     /locus_tag="OPV72_004069"
     CDS             complement(32..1315)
                     /gene="aroA"
                     /locus_tag="OPV72_004069"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HCR9916228.1"
                     /translation="MESLTLQPIARVDGAINLPGSKSVSNRALLLAALACGKTVLTNL
                     LDSDDVRHMLNALSALGINYTLSADRTRCDITGNGGPLRASGTLELFLGNAGTAMRPL
                     AAALCLGQNEIVLTGEPRMKERPIGHLVDSLRQGGANIDYLEQENYPPLRLRGGFIGG
                     DIEVDGSVSSQFLTALLMTAPLAPEDTIIRVKGELVSKPYIDITLNLMKTFGVEIANH
                     HYQQFVVKGGQQYHSPGRYLVEGDASSASYFLAAGAIKGGTVKVTGIGRKSMQGDIRF
                     ADVLEKMGATITWGDDFIACTRGELHAIDMDMNHIPDAAMTIATTALFAKGTTTLRNI
                     YNWRVKETDRLFAMATELRKVGAEVEEGHDYIRITPPAKLQHADIGTYNDHRMAMCFS
                     LVALSDTPVTILDPKCTAKTFPDYFEQLARMSTPA"
     gene            complement(1386..2474)
                     /gene="serC"
                     /locus_tag="OPV72_004070"
     CDS             complement(1386..2474)
                     /gene="serC"
                     /locus_tag="OPV72_004070"
                     /EC_number="2.6.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoserine/phosphohydroxythreonine
                     transaminase"
                     /protein_id="HCR9916229.1"
                     /translation="MAQVFNFSSGPAMLPAEVLKLAQQELRDWHGLGTSVMEISHRGK
                     EFIQVAEEAEQDFRDLLNIPSNYKVLFCHGGGRGQFAGVPLNLLGDKTTADYVDAGYW
                     AASAIKEAKKYCAPQIIDAKITVDGKRAVKPMREWQLSDNAAYLHYCPNETIDGIAID
                     ETPDFGPEVVVTADFSSTILSAPLDVSRYGVIYAGAQKNIGPAGLTLVIVREDLLGKA
                     HESCPSILDYTVLNDNDSMFNTPPTFAWYLSGLVFKWLKAQGGVAAMHKINQQKAELL
                     YGVIDNSDFYRNDVAQANRSRMNVPFQLADNALDKVFLEESFAAGLHALKGHRVVGGM
                     RASIYNAMPIEGVKALTDFMIDFERRHG"
     gene            complement(2660..3352)
                     /locus_tag="OPV72_004071"
     CDS             complement(2660..3352)
                     /locus_tag="OPV72_004071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HCR9916230.1"
                     /translation="MKAFDLQRMALDNVSVAFLGEVALRSFYTFVLVFLFLKVTGRRG
                     VRQMSLFEVLIILTLGSAAGDVAFYDDVPMLPVLVVFITLALLYRLVMWLMAHSEKLE
                     DLLEGKSVVIVEDGELAWEKLQRSNMTEFEFFMELRLNGVEQLGQVRLAILETNGQIS
                     VYFFENKDVKPGLSILPEHCTPRFIVAPEAGDYACVRCSEVIRMNVGEKQLCPRCANP
                     EWTKASRAKRVV"
     gene            3489..5249
                     /locus_tag="OPV72_004072"
     CDS             3489..5249
                     /locus_tag="OPV72_004072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     accessory protein YcaO"
                     /protein_id="HCR9916231.1"
                     /translation="MTQTFIPGKDAALEDSIARFQQKLLDLGFHIEEASWLNPVPNVW
                     SVHIRDKECALCFTNGKGATKKAALASALGEYFERLSTNYFFADFWLGETIANGPFVH
                     YPNEKWFSLTENDDVPEGLLDARLRAFYDPENELTGSQLIDLQSGNEERGVCGLPFTR
                     QSDNQTVYIPMNIIGNLYVSNGMSAGNTRNEARVQGLSEVFERYVKNRIIAESISLPE
                     IPAEVMARYPAVMESIATLEAEGFPIFAYDGSLGGKYPVICVVLFNPANGTCFASFGA
                     HPDFGVALERTVTELLQGRGLKDLDVFTPPTFDDEEVAEHTNLETHFIDSSGLISWDL
                     FKQDADYPFTDWSFSGTTEEEFATLMAIFAAEDKEVYIADYEHLGVYACRIIVPGMSD
                     IYPAEDLWLANNNMGSHLREILLSLPGSAWNKEDYLNLIEQLDEEGFDDFTRVRELLG
                     LATGADNGWYTLRVGELKAMLALAGGDLEQALIWTEWTMEFNSSVFSPVRANYYRCLQ
                     TLLLLSQEDARQPLQYLNAFIKMYGAEAVEAASTALSGEAAFYGLPAVDHDLQAFPAH
                     QSLLKAYDKLQRAKAAYWSK"
BASE COUNT         1303 a         1465 c         1331 g         1251 t
ORIGIN      
        1 cgccagcccg tcgactggcg caacagaaga attaggcagg cgtactcatc cgcgccagtt
       61 gttcgaaata atcagggaac gtttttgcgg tacatttagg gtccaggatc gtgactggcg
      121 tatcggacag tgcgaccagt gagaaacaca tcgccatacg gtggtcgttg tacgtgccaa
      181 tatccgcgtg ttggagcttc gccggcggcg tgatacgaat atagtcgtgc ccttcttcga
      241 cttcagcgcc cactttacgt agctcggtcg ccatcgcgaa caggcgatcg gtttctttca
      301 ctcgccagtt ataaatattg cgcaacgtcg tggttccttt cgcaaacaac gccgtggtgg
      361 caatcgtcat cgccgcatcc ggaatatggt tcatatccat atctatggcg tgcaattcgc
      421 cgcgcgtgca ggcaataaaa tcatcgcccc aggtaatggt cgcgcccatt ttctccagca
      481 catcggcaaa acgaatatcg ccctgcatac ttttgcggcc aatcccggtc acttttaccg
      541 tgccgccttt tatcgcccca gcggcgagaa aataggacgc tgacgaggca tcgccctcga
      601 ccagatagcg acctggagag tgatactgtt gaccgccctt cacgacaaat tgttggtagt
      661 gatggttcgc tatctccacg ccaaaggttt tcattaaatt tagcgtgata tcgatgtaag
      721 gttttgatac cagttcgcct ttaacgcgaa taattgtgtc ttcaggcgcc agcggcgccg
      781 tcatcagcag agcggtcagg aactggctgg aaacgctacc atcaacctca atgtcgccgc
      841 cgataaaacc gccgcgcaga cgcaggggcg gatagttttc ctgctccagg taatcaatat
      901 tcgccccacc ctgacgcagc gaatcgacca gatggcctat cggacgctct ttcatacgcg
      961 gttcgccggt taacactatc tcattttgcc ccagacatag cgctgccgct aacggacgca
     1021 tcgcggttcc ggcattaccg agaaacagtt ccagagtgcc tgacgcgcgt aatgggccgc
     1081 cattacccgt gatatcacag cgggtgcgat cggcagaaag ggtgtaattg atccccaacg
     1141 cgctcagggc attgagcata tggcggacgt catcgctatc cagcagattc gtcagaacgg
     1201 ttttaccaca agctaaagcc gccaggagca aagcacggtt tgaaacactt ttggagccag
     1261 gtaaattaat ggcgccatcg acccgcgcga tgggttgtaa cgtcagggat tccatgaaac
     1321 tcaactctca aaaaacagaa ataaaaaccc cacagactgg ccgtggggat gaaaaaagaa
     1381 acgtattagc cgtggcggcg ctcaaaatcg atcatgaaat cggtcagcgc tttcacccct
     1441 tcaatcggca tggcgttata gatagaggcg cgcataccgc caacaacacg gtgccctttt
     1501 aaggcgtgca gaccagcggc gaaagactct tccagaaaga ccttgtccag cgcattgtcc
     1561 gctaactgga acggaacatt catccgcgaa cggttggcct gtgcgacatc gttacggtag
     1621 aaatcgctgt tatcaatcac accatacagc aactccgctt tttgctgatt gattttgtgc
     1681 atcgccgcca cgccgccctg cgctttcaac catttgaaca ccagaccgga aagataccag
     1741 gcgaaagtcg gcggtgtatt aaacatcgag tcgttatcat tcaggacggt gtagtcgagg
     1801 atggacgggc agctctcatg cgccttgcct aacagatcct cccggacgat aaccagcgtc
     1861 agtcctgccg gaccgatatt cttctgcgcg ccagcataaa ttacgccata gcgagagacg
     1921 tccagcggcg cagacaggat ggtagaagaa aaatccgccg tgacgaccac ttccgggcca
     1981 aaatccggcg tttcatcgat ggcgatgccg tcaatggtct cattcgggca atagtgtaaa
     2041 taagcggcgt tatcggaaag ctgccactcg cgcatcggtt ttacggcacg tttgccgtca
     2101 acggtgattt tggcgtcgat aatctgcggc gcacagtatt ttttggcttc tttgatggcg
     2161 ctcgccgccc agtaaccggc atcgacataa tccgccgtgg ttttatcgcc cagcagattg
     2221 agcggcacgc cagcaaactg cccgcgaccg ccgccgtgac aaaataaaac tttatagttg
     2281 gaggggatat taaggagatc gcgaaaatcc tgctccgcct cttcagcgac ctggataaac
     2341 tctttgcctc gatggctaat ttccattacc gacgtaccaa gaccgtgcca gtcacgcagt
     2401 tcctgttgcg ccagtttaag tacttccgcc ggtagcatcg ccggacctga actaaaatta
     2461 aagacctgag ccatttcccc tcaccacgct gcattgtttc ctgcctgaca gacatcaggc
     2521 aaacgttatt catgtgaata tcggttttat cattcagtga cacgcgccgc aatgggtaaa
     2581 acaatgcgag gagaaaatgc ggcatgcgtc acacaacaga atcttccgga ttaaccgtat
     2641 aaatccgata ttttcgctgt taaacaacgc gtttagcccg gcttgccttc gtccattctg
     2701 gatttgcgca gcgcggacat aattgcttct ccccgacatt catgcgtatc acttcactgc
     2761 aacgtacgca ggcatagtcg ccagcctccg gcgccacgat aaagcgtggc gtacagtgct
     2821 caggaagaat gcttaacccc ggcttaacgt ctttattttc aaagaaatag acgctgattt
     2881 gtccgtttgt ctccaggatg gccagtctga cctgccccag ttgctcaacg ccattcaagc
     2941 gaagctccat aaaaaattca aactccgtca tgttcgagcg ctgcagtttt tcccacgcca
     3001 gttcgccgtc ttcaacaatg accaccgact tgccttccag cagatcttcc aacttttcac
     3061 tatgcgccat cagccacatg actaggcgat agagcagcgc cagggtgatg aataccacca
     3121 gaacagggag catcggaacg tcatcataaa acgcgacgtc gcctgccgcc gatcccaatg
     3181 tcaaaatgat cagcacttca aaaagcgaca tttgccgtac gccgcgtcgt cctgtcacct
     3241 ttaagaaaag aaacaccaga acaaaggtgt aaaagctacg tagcgccact tcccccaaaa
     3301 acgctaccga cacgttatcc agcgccattc gttgcaaatc aaatgctttc attttttatg
     3361 ctcttcctgt gaattccagt gtaaaagcat agccaatact tttatttccg ccgacgtccc
     3421 ggcgagatag cgcccgtcac ataaaacccg tatcattgcg cgctttccgt acgacaaaag
     3481 tgattttcat gacgcaaaca tttattcccg gcaaagacgc cgcgctggaa gactccatcg
     3541 cccgcttcca gcaaaagtta ctcgacctcg gctttcacat cgaagaggcc tcctggctga
     3601 acccggtgcc aaacgtctgg tcagtgcata ttcgcgataa agagtgcgcg ttatgcttta
     3661 ccaacggaaa aggcgcgacc aaaaaagcgg cgctggcctc ggcgctgggc gaatacttcg
     3721 agcgtctgtc aaccaactac ttttttgctg atttctggct tggcgaaacg atcgccaacg
     3781 ggccattcgt gcattatccg aatgaaaagt ggttctcgct gactgaaaat gacgacgtac
     3841 cggaaggctt gcttgatgcc cgtctgcgcg cgttttacga tccggaaaat gaactcaccg
     3901 gaagccagtt aattgatctt cagtccggca atgaagaacg cggcgtctgc ggcctgccat
     3961 ttacccgtca gtccgataac cagaccgtgt atattccgat gaatattatc ggcaacctgt
     4021 acgtctctaa cggaatgtcc gccggcaata cgcgtaatga agcccgcgtt cagggactgt
     4081 cggaagtctt cgagcgttat gtgaaaaatc gcatcattgc ggaaagtatc agtctgccgg
     4141 agattcccgc agaggtgatg gcgcgttatc cggcggtaat ggagtcaatc gccacgctgg
     4201 aagccgaggg tttcccgatt ttcgcctatg acggctcgct gggcggtaag tatccggtta
     4261 tctgcgtcgt gctgttcaac ccggctaacg gtacctgctt tgcttctttt ggcgcccatc
     4321 ctgactttgg cgttgcgctg gaacgtacag tgaccgagct actccaggga cgcggtctga
     4381 aagatcttga tgtcttcacg ccgccaacgt tcgatgatga agaagtcgcg gagcacacta
     4441 atctggagac ccacttcatc gactccagcg gcctgatttc ctgggatctg ttcaaacagg
     4501 acgccgatta cccgttcacg gactggagtt tctccggcac taccgaagaa gaattcgcca
     4561 cgctgatggc catcttcgct gctgaagata aagaagttta cattgccgat tacgagcatc
     4621 tcggcgtata cgcctgtcgt attatcgtac cgggaatgtc tgatatttat cctgccgaag
     4681 atctgtggct ggccaacaac aatatgggta gccatcttcg tgagattctg ctttcgctgc
     4741 ccggtagcgc ctggaataaa gaagactatc tcaatctgat tgaacaattg gatgaagaag
     4801 gttttgacga tttcacccgc gtgcgtgaac tgttgggtct ggcgaccgga gcggacaatg
     4861 gttggtatac actgcgcgtc ggcgaattaa aagcaatgct agcgttagcg ggcggcgatt
     4921 tggagcaggc gctaatctgg acagaatgga cgatggagtt caattcgtcg gtctttagtc
     4981 cggtacgcgc aaactattac cgttgcctgc aaacgctgct gctcctgtcg caagaagatg
     5041 cgcgtcagcc gctgcaatat ctcaatgctt ttataaaaat gtatggcgca gaggctgtag
     5101 aagccgccag caccgcgctt agcggtgaag cggcttttta tggactaccg gctgtcgacc
     5161 acgatctaca agcgttcccg gcgcatcagt ccttgttaaa agcgtatgat aaattacagc
     5221 gcgcgaaagc ggcatactgg tcaaaataag gccatatgag tgacttaggg taggtttacc
     5281 ctctcggctg cgttatatta cggggcgcct ttgcggcccc gttttattta ttttcactaa
     5341 acggcgaaaa
//
LOCUS       DAJVBX010000240         5322 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.240, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000240 DAJVBX010000000
VERSION     DAJVBX010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 5322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5322
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.240"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            296..1234
                     /gene="ghrA"
                     /locus_tag="OPV72_004073"
     CDS             296..1234
                     /gene="ghrA"
                     /locus_tag="OPV72_004073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate/hydroxypyruvate reductase GhrA"
                     /protein_id="HCR9916232.1"
                     /translation="MEIIFYHPTFNAAWWVNALEKALPHARVREWKVGDNNPADYALV
                     WQPPVEMLAGRRLKAVFVLGAGVDAILSKLNAHPEMLDASIPLFRLEDTGMGLQMQEY
                     AASQVLHWFRRFDDYQALKNQALWKPLPEYTREEFSVGIIGAGVLGAKVAESLQAWGF
                     PLRCWSRSRKSWPGVESYVGREELRAFLNQTRVLINLLPNTAQTVGIINSELLDQLPD
                     GAYVLNLARGVHVQEADLLAALDSGKLKGAMLDVFSQEPLPQESPLWRHPRVAMTPHI
                     AAVTRPAEAIDYISRTITQLEKGEPVTGQVDRARGY"
     gene            1319..2056
                     /locus_tag="OPV72_004074"
     CDS             1319..2056
                     /locus_tag="OPV72_004074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HCR9916233.1"
                     /translation="MYPVDLHMHTVASTHAYSTLSDYIAEAKRKGIKLFAITDHGPDM
                     EDAPHHWHFINMRIWPRLVDGVGILRGIEANIKNINGEIDCSGKMFDSLDLIIAGFHE
                     PVFAPHDKETNTQAMIATIASGKVHIISHPGNPKYPVEVKAIAQAAAKHHVALEINNS
                     SFLHSRKGSEDNCRAVAAAVRDAGGWVALGSDSHTAFTLGDFTECRKILDAVNFPEDR
                     ILNVSPQRLLAFLESRGMAPVPEFAEL"
     gene            2080..2634
                     /locus_tag="OPV72_004075"
     CDS             2080..2634
                     /locus_tag="OPV72_004075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HCR9916234.1"
                     /translation="MNEFSILCRVLGSLFYRQPQDPLLVPLFTLIREGKLAANWPLEQ
                     DDMLARLQKSCDITQISTDYNALFVGEECAVAPYRSAWVEGAEESEVRAFLTSRGMPL
                     ADTPADHIGTLLLAASWLEDQSAEDESEALETLFADYLLPWCNTFLGKVEAHAVTPFW
                     RTLAPLTRDAIGAMWDELQEEDEE"
     gene            2735..3217
                     /locus_tag="OPV72_004076"
     CDS             2735..3217
                     /locus_tag="OPV72_004076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001675581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HCR9916235.1"
                     /translation="MNILLSIAITTGILSGIWGWVAVSLGLLSWAGFLGCTAYFACPQ
                     GGFKGLLISACTLLSGMVWALVIIHGSALAPHLEIVSYVLTGIVAFLMCIQAKQLLLS
                     FVPGTFIGACATFAGQGDWRLVLPSLALGLIFGYAMKNSGLWLASRREQHSANTAVTK
                     "
     gene            complement(3255..4088)
                     /gene="csgG"
                     /locus_tag="OPV72_004077"
     CDS             complement(3255..4088)
                     /gene="csgG"
                     /locus_tag="OPV72_004077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli production assembly/transport protein
                     CsgG"
                     /protein_id="HCR9916236.1"
                     /translation="MPRLLILVAVLLLSGCLTAPPKQAAKPTLMPRAQSYKDLTHLPA
                     PTGKIFVSVYNIQDETGQFKPYPASNFSTAVPQSATAMLVTALKDSRWFIPLERQGLQ
                     NLLNERKIIRAAQENGTVAMNNRIPLQSLTAANIMVEGSIIGYESNVKSGGVGARYFG
                     IGADTQYQLDQIAVNLRVVNVSTGEILSSVNTSKTILSYEVQAGVFRFIDYQRLLEGE
                     IGYTSNEPVMLCLMSAIETGVIFLINDGIDRGLWDLQNKADRQNDILVKYRELSVPPE
                     S"
     gene            complement(4115..4531)
                     /gene="csgF"
                     /locus_tag="OPV72_004078"
     CDS             complement(4115..4531)
                     /gene="csgF"
                     /locus_tag="OPV72_004078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli production assembly/transport protein
                     CsgF"
                     /protein_id="HCR9916237.1"
                     /translation="MRVKHAVVLLMLFSPLTWAGNMTFQFRNPNFGGNPNNGSFLLNS
                     AQAQNSYKDPAYDNDFGIETPSALDNFTQAIQSQILGGLLTNINTGKPGRMVTNDFII
                     DIANRDGQLQLNVTDRKTGRTSTIEVSGLQTQSTDF"
     gene            complement(4558..4953)
                     /gene="csgE"
                     /locus_tag="OPV72_004079"
     CDS             complement(4558..4953)
                     /gene="csgE"
                     /locus_tag="OPV72_004079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli production assembly/transport protein
                     CsgE"
                     /protein_id="HCR9916238.1"
                     /translation="MKRYLTWIVAAELLFATGNLHANEVEVEVPGLLTDHTVSSIGHE
                     FYRAFSDKWESEYTGNLTINERPSARWGSWITITVNQDVIFQTFLFPMKRDFEKTVVF
                     ALAQTEEALNRRQIDQTLLSTSDLARDEF"
     gene            complement(4982..>5322)
                     /gene="csgD"
                     /locus_tag="OPV72_004080"
     CDS             complement(4982..>5322)
                     /gene="csgD"
                     /locus_tag="OPV72_004080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transcriptional regulator CsgD"
                     /protein_id="HCR9916239.1"
                     /translation="EIENWPHINGVFYATEDQEHVVSGLQGILRGECYFSQKLASYLI
                     THSGNYRYNSTESALLTHREKEILNKLRIGASNNEIARSLFISENTVKTHLYNLFKKI
                     AVKNRTQAVS"
BASE COUNT         1275 a         1253 c         1387 g         1407 t
ORIGIN      
        1 gatacgttgc cgtatacaca ctttccaggc gtgctccttc agccactcgg acacctcacc
       61 aaattgtcgc tccagcatta ctggaacggg cgctaatgta gggaaatatc ctttctacgt
      121 caatcaactt ttttaaaaaa aagcgctttt atacaaactt ccatcaatct gtggctttaa
      181 taagcgaaaa ctgctttttt tgcccgcgcc gggaaatttg ctatgctgca catcccgttg
      241 aaaacgctga taacaggcgc aatcacattc cgcacaatac tgctcaggag ataacatgga
      301 gataattttt tatcacccga catttaacgc cgcctggtgg gtaaatgcgc tggagaaggc
      361 tctcccacat gcgcgcgttc gtgaatggaa ggtcggtgat aacaaccccg cagactatgc
      421 gcttgtatgg cagcccccgg ttgaaatgct ggccggaaga cgcttaaaag ccgtctttgt
      481 gctgggcgcg ggggtggatg caattctgag taaattaaat gcgcatccgg aaatgctgga
      541 cgcctccatt cctctattcc gtctggaaga taccggaatg ggcctgcaaa tgcaggagta
      601 tgccgccagc caggtattac actggttccg tcgtttcgat gattatcagg cgctgaaaaa
      661 tcaggcgcta tggaaaccgt tgccggaata tacccgcgaa gagtttagcg tcggtatcat
      721 aggcgcaggg gtactgggcg caaaagtggc agaaagtcta caggcgtggg ggttcccgtt
      781 acgttgctgg agtcgtagcc gcaaatcctg gcctggcgtg gaaagttatg tagggcgtga
      841 agaactgcgc gctttcctga accagacgcg ggtgctgatt aatctgctgc cgaatacggc
      901 ccaaacggta ggaattatta atagcgaatt gttggatcaa ttgccggatg gcgcttacgt
      961 gctgaatctc gcgcgcggcg ttcatgttca ggaggcggat ctgctggctg cgcttgatag
     1021 cggtaagcta aaaggcgcga tgttggatgt ctttagccag gaaccgttac cgcaggaaag
     1081 tccattatgg cgccatccgc gagtcgccat gacgccgcac attgcggcag tcacccgtcc
     1141 ggcggaagcc atcgattata ttagccgcac cattacccag ctggagaagg gagagccggt
     1201 gacggggcag gtggatcggg cgagaggata ttgatatcaa cccggcgcgg gccgggtttc
     1261 gctaaaaaac gctggcgata cctgctatcc ttgtcggaaa tgactacagg agagagcaat
     1321 gtatcccgtt gacctgcata tgcataccgt cgccagcact catgcctaca gtactctgag
     1381 cgattatatc gcggaagcca aacgcaaagg cattaaactt tttgcgatta ccgatcatgg
     1441 tccggacatg gaagatgcgc cgcatcactg gcattttatt aacatgcgca tctggccgcg
     1501 tctggttgac ggcgtgggga tactgcgtgg cattgaggcg aatatcaaga atattaacgg
     1561 tgaaattgat tgttccggaa agatgttcga ctcgctggat ctgattatcg caggctttca
     1621 tgagcccgtt tttgcgccgc atgataaaga aaccaatact caggcgatga tcgcgaccat
     1681 cgccagcggc aaggtgcata taattagtca ccccggaaat ccaaagtatc cagtggaggt
     1741 taaagccatc gcgcaggcgg cggcgaaaca ccatgtagcg ctggaaatca acaactcttc
     1801 ttttctgcat tcgcgtaaag gaagcgaaga taattgccgc gcggtcgctg ccgccgtacg
     1861 cgatgcggga ggctgggtag cgttaggctc tgattcccat acggccttta cgcttggcga
     1921 tttcaccgaa tgccggaaaa ttctggatgc ggtgaatttt ccggaagatc gaatcctgaa
     1981 cgtctctccg cagcgcttac tggcctttct cgaatcacgc ggtatggcgc ctgtaccgga
     2041 atttgccgaa ctttaatcgt tatttacggg aagatatcaa tgaatgagtt ttcaatcctg
     2101 tgccgtgtgc tgggatcgtt gttttaccgc caaccgcaag atcctttact ggttccgctg
     2161 tttacgttaa tccgtgaagg taaactggcg gcaaactggc cgctggagca ggatgacatg
     2221 ctggcgcgtt tacagaaaag ctgcgatatc acgcagattt ccactgatta caatgcgtta
     2281 tttgttgggg aagagtgcgc ggtagcgcca taccgcagtg cgtgggtcga aggcgcggaa
     2341 gagtctgagg tgcgcgcttt tttaacgtcg cgagggatgc cgctggccga tacgcctgcc
     2401 gatcacattg gcactttatt gctcgcggcc tcctggctgg aagatcagtc tgccgaagat
     2461 gaaagtgaag cgctggaaac cttatttgcc gattatctgc ttccctggtg caataccttc
     2521 ctcggtaaag ttgaagccca tgccgttacg ccattctggc gcactctggc gccgctaacg
     2581 cgtgatgcga taggggccat gtgggatgaa cttcaggaag aagatgaaga ataatgtgat
     2641 gtaaatcacc attaactgca acgggttttg catcattgca taaaatgtgt gcgtgatctc
     2701 attaatgtgc cgcttttctg ttatgatgcg cgccatgaac atacttcttt ctattgctat
     2761 cactacgggc atcctttctg gaatatgggg atgggtggcc gtctccctgg ggttactaag
     2821 ctgggccggt tttttaggct gtacggctta tttcgcctgt ccgcagggcg gctttaaggg
     2881 attgttgatt tccgcctgta cgctgttaag cggtatggtg tgggcgctgg tcattattca
     2941 cggtagcgcg ttggcgccgc atctggaaat tgtcagttac gtgttgacgg ggatcgtggc
     3001 attcctgatg tgtatccagg caaagcagct attgctttct tttgttccgg gaacatttat
     3061 cggcgcctgc gcgacatttg cagggcaggg tgactggcgg ttggtattac cgtcgctggc
     3121 gctggggcta atctttggct atgccatgaa aaatagtggg ctatggctgg catcacgccg
     3181 cgagcaacat tcagcgaata cggcggtcac aaaataaaaa agcgtggggt tttccccacg
     3241 ctttgtcgta ttcatcagga ttctggcggt actgacagct cacggtattt caccagaata
     3301 tcattttgcc tgtccgcttt attctgcaaa tcccacagtc cgcgatcgat accatcatta
     3361 atgaggaaga taacgccggt ttcaatggct gacatcagac acagcatcac cggttcgttc
     3421 gaggtatagc cgatttcgcc ttccagtaag cgctggtaat caataaaacg gaacacgcct
     3481 gcctgtactt cataggaaag gatcgtttta ctggtgttca ccgaagaaag gatctcgccc
     3541 gtactgacgt taaccacgcg caggttgaca gcaatctgat ccagctgata ctgcgtatcg
     3601 gcgccaatac cgaaatatct tgcgccgacc ccgccggatt tgacgttact ttcataacca
     3661 ataatagaac cttccaccat aatatttgcc gccgtcaacg actgaagcgg gatacggtta
     3721 ttcatcgcca cggtgccgtt ttcctgggct gcgcgaataa ttttccgttc attcaaaaga
     3781 ttctgtaagc cttgtcgttc tagtgggata aaccagcgcg aatctttcag cgcggtgacc
     3841 aacatagcgg tggcgctctg cggcacagcc gtggaaaagt tacttgccgg gtaaggttta
     3901 aattggcccg tttcatcctg aatgttatat accgaaacaa agatcttacc ggtgggagca
     3961 ggtaagtgcg tcaaatcttt gtaactttgt gcgcggggca ttaatgtcgg tttcgcagct
     4021 tgtttcggcg gggcagttaa gcatccgctc aacaataaaa cggcaaccaa aataagtaag
     4081 cgcggcatga tttatatcct ttagtgactg tagcttaaaa atcggttgac tgagtttgta
     4141 aacctgacac ttcgatggtc gaggttcttc ccgtttttct gtccgtgacg ttgagctgga
     4201 gctgtccgtc gcgattagcg atatcgataa taaaatcatt ggtcaccata cgtcctggtt
     4261 ttccggtatt aatattggtc aacaagccgc ccagaatttg cgattgaata gcctgcgtaa
     4321 agttatccaa cgctgagggg gtctcgatac caaaatcgtt atcataagcg gggtctttat
     4381 atgaattttg cgcctgggcg ctattcaata aaaaggaacc gttattgggg tttccaccaa
     4441 agttaggatt acggaactgg aacgtcatat ttccagccca ggttaatggc gaaaaaagca
     4501 tgagcagcac tactgcatgt ttaacacgca tgacagcctc cggataaaaa tcatgtttta
     4561 gaattcatca cgcgctaaat cactcgtact taatagcgtt tgatctattt gtcggcgatt
     4621 taatgcttcc tctgtttgcg ctaatgcgaa gacgacggtt ttctcgaagt ctcttttcat
     4681 tggaaataaa aaggtctgga aaataacgtc ctgatttacc gttatggtga tccagcttcc
     4741 ccaacgcgca ctgggtcttt cattaatggt cagattgccg gtgtattcgc tttcccattt
     4801 gtcgctgaat gcacgataga attcatgtcc tatcgaagag acggtatggt cggttaacaa
     4861 tccgggaacc tcgacttcaa cttcattggc atgcaggttt ccggtagcga acagtaactc
     4921 tgctgctaca atccaggtca gatagcgttt catggcctta ccgcctgaga ttatcgtttg
     4981 ctcatgaaac tgcctgggtg cgatttttga cagctatctt tttgaaaaga ttataaagat
     5041 gtgtcttaac cgtattctcg ctgataaata gcgacctggc gatttcatta ttagaggcac
     5101 caatacgtaa cttattgagg atctcttttt cgcgatgagt gagtaatgcg gactcggtgc
     5161 tgttgtagcg gtaatttcct gagtgtgtaa tcaggtaact ggctaatttt tgtgaaaaat
     5221 agcattcgcc ccgcagaata ccctgtaatc cgctgaccac gtgttcctgg tcttcagtgg
     5281 cgtaaaacac gccgttaata tgaggccagt tttcaatttc ac
//
LOCUS       DAJVBX010000241         5157 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.241, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000241 DAJVBX010000000
VERSION     DAJVBX010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 5157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5157
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.241"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            90..1985
                     /locus_tag="OPV72_004081"
     CDS             90..1985
                     /locus_tag="OPV72_004081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001671148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitinase"
                     /protein_id="HCR9916240.1"
                     /translation="MQGNMSQPGRGCDLTNVSPTAYDKLIFGFVGITGFRKIDKEDRD
                     VVAEAAALCGKVKYEPTFLDPWGDFQSYINLGFETSGWDVDPKTVTQANAKGMLGALR
                     DMQAKAKAAGHTLALSMSIGGWSMSNGFHETAASDSSRKTFAKGVVKLFKQFPMFSEV
                     DIDWEYPNDEGAGNPFGAEDGANYALLIAELRKQLDSAGLSNVKISIAASAVTTIFDH
                     AKVKDLLAAGLYGINLMTYDFFGTPWAETLGHHTNRKALEEGGWAVETIVDHLLAEGF
                     SADRINIGYAGYTRNARQVEIESLSPLKGSYNPGSGDTTGSFESGTSEWYDVIYSYLD
                     LENQKGRNGFNVYTDQVADADYLYSPESKLFLSLDTPRTVKAKGEYAAKLGLGGVFTW
                     TIDQDNGVLVNAVREGLGYEIESEVIDMEPFYFEGINVEKDDEQSDSDDAQKVNHAPK
                     AAIELMVVGGSTVQLSGAGSSDEDNDELSFSWGVPSQIDVADKTAEIIEVVVPEVSEK
                     TAFQFTLFVRDCYNEPSSQQRFVLTAVPALSQVQPEPEEEEEIIVPVPDEEEETTPAE
                     DDTSADDKTSPYAQWDASTVYGANWGSFEIVSWKGHNYQVKWWSMGNQPDLNCGVGGA
                     WTDLGAY"
     gene            2077..5073
                     /locus_tag="OPV72_004082"
                     /pseudo
     CDS             2077..5073
                     /locus_tag="OPV72_004082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459024.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="chitinase"
BASE COUNT         1212 a         1324 c         1427 g         1194 t
ORIGIN      
        1 cgaaaccggt atacaataaa tataaaaatt ccacgactaa gccgaaggta ttcggttatt
       61 acaccgactg gtcacagtat gacagccgtc tgcaaggcaa tatgtcccaa ccgggccgtg
      121 gttgtgattt aaccaatgtt tcaccgacgg cttatgacaa actgattttt ggttttgttg
      181 gtatcaccgg tttcagaaaa attgataaag aagaccgcga cgtcgtagca gaagcggcag
      241 cgctgtgcgg caaagtgaaa tatgagccga ccttcctcga tccgtggggc gatttccagt
      301 cttatatcaa cctgggtttt gaaaccagcg gctgggatgt tgatccgaaa accgtgaccc
      361 aggctaacgc taaaggtatg ctgggcgcgc tgcgtgatat gcaggcaaaa gcgaaagctg
      421 caggtcacac gctggcgctc tccatgagta tcggcggctg gagcatgagt aacgggttcc
      481 acgaaaccgc cgcttctgac tcttctcgta aaaccttcgc caaaggcgtg gtgaaactgt
      541 tcaaacagtt cccgatgttc agcgaagtgg atattgactg ggaatacccg aacgatgaag
      601 gggcgggcaa cccgtttggc gcagaagatg gcgctaacta cgcgctgctg attgccgaac
      661 tgcgtaaaca gctggattcc gcgggtctga gcaatgtgaa gatctctatc gcggcctccg
      721 cggtgaccac gatttttgat cacgctaaag taaaagatct gttggctgct ggcctatacg
      781 gcatcaacct gatgacctat gacttcttcg gtacgccgtg ggcggaaacg ctgggccacc
      841 acactaaccg caaagcgctg gaagagggcg gctgggctgt cgaaaccatc gttgatcacc
      901 tgctggcgga aggtttctcc gctgaccgta tcaacatcgg ttatgccggc tatacccgta
      961 acgctcgtca ggtagaaatt gaatccctgt cgccgctgaa aggttcttac aacccaggtt
     1021 caggcgatac taccggttcc ttcgaatccg gcaccagcga atggtatgac gtcatttata
     1081 gctacctgga tctggaaaac cagaaaggcc gtaacggttt caacgtttac accgaccagg
     1141 tcgctgacgc tgactacctg tatagcccgg aatccaaact gtttttatcc ctggatacgc
     1201 cgcgtactgt caaagcaaaa ggcgaatatg cagcgaaact gggcctgggc ggcgtgttta
     1261 cctggactat cgatcaggac aacggcgtgc tggttaacgc cgtgcgtgaa ggtctgggtt
     1321 atgaaatcga atctgaagtt atcgatatgg aaccgttcta cttcgaaggt atcaatgtag
     1381 aaaaagatga cgagcagagc gatagcgacg acgcgcagaa ggtcaaccac gcgccgaaag
     1441 cggcgattga actgatggtc gtaggcggat cgacggtaca gctgtctggc gcaggttctt
     1501 ctgatgaaga taacgatgag ctgtccttta gctggggcgt gccttctcaa atcgatgtgg
     1561 cagacaaaac ggcagaaatc attgaggttg tggtaccgga agttagcgaa aaaacagcct
     1621 ttcagttcac cctgtttgta cgcgactgct acaacgaacc gtcctctcaa cagcgctttg
     1681 ttctgacggc ggtgcctgcg ctatctcagg ttcaaccgga accggaagag gaagaagaga
     1741 ttatcgttcc tgtaccggac gaggaagaag agaccacgcc ggctgaggat gatacgtcag
     1801 cagatgacaa aacgtcacct tacgcgcagt gggatgcttc taccgtttat ggcgcaaact
     1861 ggggttcttt cgaaatcgtt agctggaaag gccataacta tcaggtgaaa tggtggtcta
     1921 tgggcaacca gcctgacctg aactgtggtg tcggcggtgc atggaccgat cttggcgctt
     1981 actaatacac ggtattaagc cgatgtattg ggcttcatga ttcaagcccc ggtttaccgg
     2041 ggcttttctc caccagggac agaggaagag cagaccatga ccatttccat ccatgccagc
     2101 gcatttgacg tcaacagctg gtatcaaaaa atcaccttaa ccttcatcaa tgagagcggt
     2161 aatccggtcg atatgaacca tgccgcaata tcattcacgg cttccgggca catcgatcca
     2221 tggggaaata gcggcggtac gctcaaaggg aacccgccgc ttacgctgaa tgatagttcg
     2281 tatggcacgc tggaaactaa caacatcatc attaataaca gcgatgcatt acttcttcag
     2341 ccgggcgaac gcggaacgct ctctttcagc ctcgcggcga cgcaggtgcc ggtaaaaatg
     2401 tccgccgtca ccttgacgct ggcgtcatcg tcatccgaag acgcagagtc tgcaacccca
     2461 tccgatcagg agacgccagc gatacccgcc gcagacgaac aacccgccga atccgatgtg
     2521 ccggaaaagg acaatgacct tcaggaacgc ggccttacgc ttaacgttag cgagttgaat
     2581 gccgcaagtt ggtatcaaca cgtcaccttt acgctgacca gcctctacgc ccaggcggta
     2641 gatctcaatc agcttcaact gaattttacg gccagcgcgc accccgatcc ctacagtccg
     2701 tttcagggaa caatgctggg gaatcaggcc gtgacgctgg ccagcgatgg gggatggccc
     2761 atcgagaaga ataccatcac cattaatcat gacggcgcgc tgatgctggc ggcaggggat
     2821 atcgccgaat tacagtgcta tctggccgcc acgcagacgc cagttgccat cagcgatttg
     2881 aacgcgacgt tggcccatga ccctgcccac cagggaaaaa tttgcgttca ctttcctgcc
     2941 atgacgcaga ccgtggcgct caaaccggtg attgagctac tgtttcctgc cggcgaaacc
     3001 cggcgctttg tcggtgagtg gggagaggtt ctgacaataa gcgatcttag cgcaggaacg
     3061 tatcggctta tcgtaccggt actggcgaat gatgagatgc aaatcgcgcc agtcgagtcc
     3121 tcttttaccg ttacgctgca atccggagat gccgccgcgc aggtctaggt atcttgttta
     3181 ccgattgtcc attatgccag cgcgcgtctg atgattgatg cccctgcgct tggtaatgcg
     3241 aaattgaccg ttgaaatcgc cgatgctacg caagcggatg agcgtaccgt cacgcttatc
     3301 gccaaccaac cgcagttaat cacccggcta ctggcggggc atcattatac ggtcaatctg
     3361 cagcctgcga tgattaataa ccgctttata tcggcaccca tacagcttac gggttttatc
     3421 cctgctgcgg cgcaggttgc cgaggttgct gtcgcttacc aacagtcggc gctcgacacg
     3481 gcgagcttcg tgacggtaga tgccactata ctgggcctgc ccgatggcgt cgcgccgcag
     3541 cgttatctgt tcagcagcgg taaatatcaa tactcattaa tgctggagag cggcagcgat
     3601 cggcagacgc tgtcattacg ctttgcgccc gggctgtatg atgttcagac ggacgatatt
     3661 ttcatcgaca gtgtgccgtg gcgttgtgaa caggccgggc cgctacgctt gttgcaaaag
     3721 gtcaaccatg tggcgctgga gtttctgccc ggcgtgacgc tacaggtaaa aggttggcct
     3781 gattaccttg ctcatggcgg cgtgacggtt aacgcgccag agacggtttc tctttatcgc
     3841 gatataccgt ttagcgcgtt gtttaaatac gacggttttg acggcggcgg cgatccggtg
     3901 ccggccgcag aggttgacgt gaacggggat gtttttctgg attacgcgac attaccgatc
     3961 cataaaaccg ttgcgctggt gcgccagatc gaaaaagaag ccgggcgtag cgtcatgccg
     4021 gtaatggtca tttataccgc gaatgccagc ggcggcagcg cgctggtgga tttacaggat
     4081 gcgcaaaagc tacgtaacca ttttggtaac tttattaccc agtgtctggc ggcgcagtca
     4141 tacaaagatg agacgcatcc tgtcccggcc acctttgtgc ttaacccgga ttttctgggt
     4201 gcgctacagc aaggaccgta tggctatacc gtagtacggc aaaaaaacag tgtgccggtg
     4261 aatgcccaac tggcggcggc gatacaagca ttaccggcga tggctggctt tatcgcgcct
     4321 tcgttgccga cgtttagcga cgatctctac ggttatattc aggcggtgaa ctatcttgtt
     4381 cgtcagtttg ccccggatgt ggcttttggc tggcagacga atgtctgggc gacaggaacg
     4441 gcggactggg tgctgcgcga taccgctgat ccggtagctg aagggcaggc gatcgccgga
     4501 tttattcatg aactgggcgt ttatagcgga gaatatgcgc cggactttat tgcgtttgat
     4561 gaatttgagc gtgactgttt cagtcctgat gcgcttgccc actatggctg gaatgcgaca
     4621 tgctggctta attacctggc gatggtaaaa caggtgacga aagcgctgct gacgcccgcc
     4681 atgctgtggc aaattcctgg cggccatatg cctacagtag aagagggcgt cagcaaaatc
     4741 agcgctgcgc actttgcatc cggcggaacc ttttttatgg gtgacgcccg cattggcagc
     4801 gatcctgaca cgctctcttt gcagctactc aatacggcct taaatagcgc gacttacggc
     4861 gtcccgaccg tcggcgactt tttacgtaaa gataaagggt atgactgggg ccagatgcag
     4921 gcgctgaacc taccggactt taacgtcttt tcgatcttat ggggcggtgg ttctactatc
     4981 agtattacga caatccattc taacggtgaa gacggcggct ggctggcgga taaaatggta
     5041 gagtattatg ctgctccacg ctattttaga taatatcact gcttatttgc attaatctgg
     5101 cctattagtt tgagattcga aggcgcgttc tttcgaatct cttttcctgc gccccct
//
LOCUS       DAJVBX010000242         5067 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.242, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000242 DAJVBX010000000
VERSION     DAJVBX010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 5067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5067
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.242"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(216..1883)
                     /gene="glnS"
                     /locus_tag="OPV72_004083"
     CDS             complement(216..1883)
                     /gene="glnS"
                     /locus_tag="OPV72_004083"
                     /EC_number="6.1.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase"
                     /protein_id="HCR9916241.1"
                     /translation="MSEAEARPTNFIRQIIDEDLASGKHTTVHTRFPPEPNGYLHIGH
                     AKSICLNFGIAQDYQGQCNLRFDDTNPVKEDIEYVDSIKNDVEWLGFHWSGDIRYSSD
                     YFDQLHAYAVELINKGLAYVDELTPEQIREYRGTLTAPGKNSPFRDRSVEENLALFEK
                     MRTGGFEEGKACLRAKIDMASPFIVMRDPVLYRIKFAEHHQTGTKWCIYPMYDFTHCI
                     SDALEGITHSLCTLEFQDNRRLYDWVLDNITIPVHPRQYEFSRLNLEYTVMSKRKLNL
                     LVTDKHVEGWDDPRMPTISGLRRRGYTAASIREFCKRIGVTKQDNTIEMASLESCIRE
                     DLNENAPRAMAVIDPVKLVIENYPQGESEMVTMPNHPNKPEMGSREVPFSGEIWIDRA
                     DFREEANKQYKRLVMGKEVRLRNAYVIKAERVEKDAEGNITTIFCTYDADTLSKDPAD
                     GRKVKGVIHWVSVAHALPIEIRLYDRLFSVPNPGAAEDFLSVINPESLVIKQGYGEPS
                     LKAAVAGKAFQFEREGYFCLDSRYATADKLVFNRTVGLRDTWAKAGE"
     gene            complement(2094..4046)
                     /gene="nagE"
                     /locus_tag="OPV72_004084"
     CDS             complement(2094..4046)
                     /gene="nagE"
                     /locus_tag="OPV72_004084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetyl glucosamine transporter subunit
                     IIABC"
                     /protein_id="HCR9916242.1"
                     /translation="MNILGFFQRLGRALQLPIVVLPVAALLLRFGQPDLLNMPFIAQA
                     GGSIFDNLALVFAIGVASSWSKDSAGAAALAGAVGYFVMTKAMVTINPEINMGVLAGI
                     ITGLVGGAVYNRWSGIKLPDFLSFFGGKRFVPIATGFFCLVLAAIFGYVWPPVQHGIH
                     AGGEWIVSAGALGSGIFGFINRLLIPTGLHQVLNTIAWFQIGEFTNAAGTVFHGDINR
                     FYAGDGTAGMFMSGFFPIMMFGLPGAALAMYFAAPKERRPMVGGMLLSVAITAFLTGV
                     TEPLEFLFMFLAPLLYLLHAILTGISLFVATLLGIHAGFSFSAGAIDYVLMYNLPAAS
                     NNVWMLLVMGVVFFIIYFLLFSAVIRMFNLKTPGREDKVDEMVTEEANSNTEEGLTQL
                     ATSYIAAVGGTDNLKAVDACITRLRLTVNDSARVNDAACKRLGASGVVKLNKQTIQVI
                     VGAKAESIGDEMKKVVARGPVAAASADAAHVATPAPAAKPQAVPNAVTIAELVSPITG
                     EVVALDQVPDEAFASKAVGDGVAVKPTDKTVVSPAAGTIVKIFNTNHAFCLETEKGAE
                     IVVHMGIDTVALNGQGFKRLVEEGAEVTAGQPVLELDLDFLNANARSKISPVVCSNSD
                     DFSALVIKADGHVVAGQTPLYEIKSK"
     gene            4373..>5067
                     /gene="nagB"
                     /locus_tag="OPV72_004085"
     CDS             4373..>5067
                     /gene="nagB"
                     /locus_tag="OPV72_004085"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008805656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HCR9916243.1"
                     /translation="MRLIPLSTAEQVGKWAARHIVNRINAFKPTTDRPFVLGLPTGGT
                     PLTAYKALVEMHKAGEVSFKHVVTFNMDEYVGLPKEHPESYHSFMHRNFFDHVDIPAE
                     NINLLNGNAPDIDAECRQYEEKIRSYGKIHLFMGGVGNDGHIAFNEPASSLASRTRIK
                     TLTHDTRVANSRFFDGDVNQVPKYALTVGVGTLLDAEEVMILVLGHQKAQALQAAVEG
                     NVNHMWTISCLQL"
BASE COUNT         1242 a         1399 c         1274 g         1152 t
ORIGIN      
        1 ttgacttgtt ttccataggc atgaaaataa ttgtctcctg ttgacctgac gcttataaca
       61 tttagattaa taatcattta tcagatcaat aattttcaga gaataattaa ttcgcctcgc
      121 aaaaaagaga atcgacttag aaatgcagag aaaaaacgcc gcagaacgcg gcgttgacaa
      181 ggtattttta cagcattcgc ctgttggcgc agtgcttatt cgcccgcttt cgcccaggta
      241 tcacgcaggc ccacggtgcg gttaaagacc agcttatcgg ccgttgcata gcggctgtca
      301 aggcagaagt aaccttcacg ttcaaactgg aaagctttcc ctgctaccgc cgctttcagc
      361 gacggctcgc catacccctg cttaatcact aatgattcgg ggttgataac agacaggaag
      421 tcctccgcgg cgcccgggtt cggcacgctg aacagacggt cgtagagacg aatttcaatc
      481 ggcagcgcat gtgctacgct aacccagtgg attacgcctt tcactttacg cccgtcagcc
      541 ggatctttac tcagcgtatc agcatcatag gtacagaaga tggtggtgat attcccttcg
      601 gcatccttct ctacgcgctc cgctttaatg acgtaggcat tacgcagacg cacttctttg
      661 cccatcacca gacgtttgta ctgtttgttc gcttcttcgc ggaaatccgc gcgatcgatc
      721 cagatctcac cgctaaacgg cacttcacgg ctgcccatct ccggtttatt cggatggtta
      781 ggcatggtaa ccatttcgct ctcgccctgc gggtagtttt cgataaccag ttttaccgga
      841 tcgattaccg ccatcgcgcg cggcgcgttt tcgttcagat cttcgcgaat gcaggattcc
      901 agcgacgcca tctcaatagt gttgtcctgc ttggtgacgc cgatgcgttt gcagaactca
      961 cgaatagaag ccgcggtata gccgcgacgg cgcagaccgg aaatagtcgg catacgcgga
     1021 tcatcccaac cttcgacgtg tttgtcggtc accagcaggt tcagcttacg cttggacatc
     1081 acggtgtatt ccagattcag gcgcgagaat tcgtactggc gcgggtgaac cggaatggtg
     1141 atgttgtcca gcacccagtc gtacagacga cggttgtcct ggaactccag cgtacacaga
     1201 gaatgagtaa tgccttccag cgcatcgctg atgcagtgag taaagtcgta catcggatag
     1261 atgcaccact tcgtgccggt ctgatgatgc tcggcgaatt taatgcgata cagcaccgga
     1321 tcgcgcatca cgataaacgg cgacgccatg tcgattttag cgcgcagaca ggctttaccc
     1381 tcttcaaaac cgccggtacg cattttttca aatagcgcga ggttttcttc cacgctgcga
     1441 tcgcggaacg ggctgttttt acccggcgcg gtcagcgtac cacggtattc gcggatctgc
     1501 tccggcgtca gctcatcaac gtaggccagg cctttattga tgagctcgac cgcataggcg
     1561 tgcagttggt caaagtaatc ggaggagtag cgaatatcgc cagaccagtg aaagcctaac
     1621 cactcgacgt cgtttttgat cgaatcaacg tactcgatat cttcttttac cgggttggtg
     1681 tcatcgaaac gcaggttgca ctggccctga taatcttgcg cgatgccaaa gttcaggcag
     1741 atagatttcg cgtggccgat gtgcagatag ccattcggct ccggcggaaa acgggtatgg
     1801 acagtggtat gtttaccact cgccagatct tcatcaataa tctgacgaat aaagttagtc
     1861 gggcgggctt cagcctcact catcgtggat tcctcaaagc gtaaacaacg tataacggca
     1921 tatgatctta taagccggac agactgacaa cctttagtta cttaaaaagt ggctttgcag
     1981 aaaatattgg ggctaattgc ggtaaaaaaa agcggcgaag gtttccctct gccgcttatg
     2041 tttcctgtga tatcgccgga tggcgtctta cgccttatcc ggccaggaag cgattatttg
     2101 ctcttgatct cgtacagcgg cgtttgaccc gctaccacgt gaccatccgc tttgatgacc
     2161 agagcgctga agtcatcgct gttgctgcaa acaaccgggc ttatcttgga acgcgcattg
     2221 gcattcagga agtccagatc cagttccaga accggctgac ccgccgtgac ttccgcaccc
     2281 tcttctacca gacgcttgaa gccctgaccg ttcagcgcga cggtatcgat acccatatgg
     2341 acaacgatct ccgcgccttt ttcggtttcc agacagaacg cgtggttagt gttgaagatt
     2401 ttcacgatag tacccgccgc cggagaaacc acggttttat cggtgggttt caccgccacg
     2461 ccgtcgccga ccgctttgct ggcgaaagct tcatccggta cctgatccag cgccactacc
     2521 tcaccggtaa tcggagagac cagttcagcg atagtcaccg cattcggcac cgcctggggt
     2581 ttggccgccg gagcaggtgt cgcaacgtga gccgcatcag cagacgctgc cgcgaccggc
     2641 ccccgcgcca ccactttctt catttcatcg ccaatcgatt ccgctttcgc gccgacaata
     2701 acctgaatgg tctgtttgtt cagtttcacc acgccggaag cgccgaggcg tttgcaggcc
     2761 gcatcgttga cgcgagcaga gtcgttcacg gtcaggcgca gacgggtaat gcacgcatcg
     2821 accgctttca ggttgtccgt accgccaacc gcagcaatat agctggtcgc cagttgcgtt
     2881 aacccttctt cggtgttgct gttggcttct tccgttacca tctcatcaac tttatcttcg
     2941 cggcccggcg ttttcaggtt aaacatacga ataaccgcgc tgaacagcag gaagtagatg
     3001 ataaagaata caacgcccat caccagcaac atccagacgt tattgctggc cgcaggcagg
     3061 ttatacatca gaacatagtc gatcgcgcct gccgagaaag agaagcccgc atggataccc
     3121 agcaacgtcg cgacgaacag gctgatacca gtcaaaatgg cgtgcaggag gtacagcagc
     3181 ggcgccagga acataaacag gaattccagc ggctcggtta cgccggtcag aaacgcggtg
     3241 atcgcgacag acagcagcat accgcccacc atcggacgac gttctttcgg cgcggcgaaa
     3301 tacatcgcca gagcggcgcc cggcagacca aacatcatga tcgggaagaa gccggacata
     3361 aacatccccg ccgtgccgtc gccagcatag aagcggttga tgtcgccgtg gaatacagtg
     3421 cctgcggcat tggtgaattc gccaatctgg aaccaggcga tggtgttcag tacctgatgc
     3481 agaccggtgg ggatcagcag acggttgatg aagccaaaga taccggaacc caacgcgcct
     3541 gcggaaacga tccattcacc gcccgcatgg atgccatgct gtaccggcgg ccagacgtaa
     3601 ccgaaaatag cggccagcac cagacagaaa aagcccgttg cgatcggcac aaaacgtttt
     3661 ccaccgaaga aactgagaaa atcaggcagt ttgataccag accagcgatt ataaaccgcg
     3721 ccgccgacca gaccggtaat aatccccgcc agcacgccca tgttgatttc cgggttaatc
     3781 gtcaccatcg ctttggtcat gacgaagtaa cccacggctc ccgccagtgc tgccgcgcct
     3841 gcgctatctt tagaccaact ggaggccacg ccgatagcga aaaccagcgc caggttatcg
     3901 aaaatagacc cgcccgcttg cgcgataaac ggcatattca gcaaatctgg ttggccgaat
     3961 cgcagcaaca acgctgccac cggcaacacg acgataggga gctgcaacgc cctacccagc
     4021 cgctggaaaa aacctaaaat attcatctta ttccccctac gagacgccga tatggcttct
     4081 ttgaagccgt tttttattgt gctgcaaacg ttaaaaacgt gatgttctgt aatcgaacgg
     4141 tgagatcatc ttctgcagag tgtgtggaaa attaattcgc ctcgcaaatt aaacgggtgt
     4201 tttttgtgat tataatcact aaatatcgta atcaccccca ccatccactg gctaacacgg
     4261 aaaacttatt ttatgattca aaaaatcagg acggattgaa cacgaaccct ggatatccag
     4321 gttacgctta atacgatccg ccaaattttg acattgatta ttgaggtgaa gaatgagact
     4381 gatccccctg agtaccgcag aacaggttgg caaatgggcc gctcgccata tcgttaaccg
     4441 tattaatgcg ttcaaaccga ccaccgatcg tccgtttgtt cttggactgc ctaccggcgg
     4501 cacgccgcta acggcgtaca aagcgctggt tgagatgcac aaagcgggcg aggtcagctt
     4561 taagcatgtg gtcaccttta atatggacga atatgttggc ctgccgaaag agcacccgga
     4621 aagctaccac agctttatgc atcgtaactt tttcgatcac gttgatattc cagcagaaaa
     4681 catcaatctt ctcaacggta acgcaccgga tatcgatgca gaatgccgtc aatatgaaga
     4741 aaaaattcgt tcttacggta aaatccatct gtttatgggc ggcgtcggca acgacggtca
     4801 catcgccttt aacgaaccgg cgtcttccct ggcttcccgt acccgtatca aaacgttaac
     4861 ccatgatact cgcgtagcga actcccgctt ctttgacggc gacgtaaacc aggtgccgaa
     4921 atacgcgctg acggtaggcg tgggtacgct gctggatgcg gaagaagtga tgattctggt
     4981 gctgggccat cagaaagccc aggcgctgca ggcggcggtt gaaggcaacg tcaaccacat
     5041 gtggaccatt agctgcctgc aactcca
//
LOCUS       DAJVBX010000243         5026 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.243, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000243 DAJVBX010000000
VERSION     DAJVBX010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 5026)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5026)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5026
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.243"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            29..1215
                     /locus_tag="OPV72_004086"
                     /pseudo
     CDS             29..1215
                     /locus_tag="OPV72_004086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141078.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
     gene            1225..1932
                     /locus_tag="OPV72_004087"
     CDS             1225..1932
                     /locus_tag="OPV72_004087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001786138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1266 domain-containing protein"
                     /protein_id="HCR9916244.1"
                     /translation="MFLLLPPYFLAGATTKKNKPLIAARIAEEKEKDRLKDLRRDTRR
                     RQWALALADILARRNGLPIKGVELVFKLDDDKHRYLAQQVKKELGLSENLNGAALRHK
                     VEDILRRWPAGIGSSPSTFYHHLAAQGQVRDALAFDCMRTAFLTRCIAGLGWCDENEA
                     WLVLLLNAQRAQDCFDSWEDYATAYVRARRVWLTLRDTPIALAGRDLQEATHYLQDPV
                     SRWRQLPWNEFKIFEPI"
     gene            1943..4054
                     /locus_tag="OPV72_004088"
     CDS             1943..4054
                     /locus_tag="OPV72_004088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4034 domain-containing protein"
                     /protein_id="HCR9916245.1"
                     /translation="MEQDDRLLNAMFEMCNHKNPLNDGQREWHIADIPGLLREERYDE
                     LDERYNQALTESFTSREAEKRYFFAWNQMDNPFYDMDTLVEAGPQGLALIKNWQRARP
                     RSTHAWLAEAQYWNHRAWLYRSYGWARETTRAMWICAAACNERMVIAALNAIDCEPRQ
                     WMAAALTSTNSKVFGQPDWLVEFLEGADVAGQPLMEDLAEYHRHSPQEVDALMAHSGL
                     SFADAVCPNLPRPSVLPECNDDAGQKYWLAVCLAIFPTAFYVLDEYIPFRMPRWGGSH
                     EEIREFLESSVCDHLSAAEREHLELLIWWDDHRDLRIKEVDSPAEQERIIAKAEEISL
                     RAHIQESRHNTLKWLRVCYSDLDDNDALWRTLQRSIVEKVKFNNYFFDDTIKFALRDF
                     PDTWWMYNFLCQNAQQTEFAVPKIRRGYFQYAGLLGFEKDEAQGLAWLDSVADIQYNH
                     NWRAAIKNFDWFGLPEHFVPLAELGAQRNIPAALNLLGLEHNNKENNGLLPYDPAIAL
                     GYFQRAAEILHRRLALRESTPYKLIDNGGYTDYENDLQNIHFSIGICNQRLSKQELDT
                     EKRSAYEKELLDNLWLAHQFGHKEAWGLFLLNIFEVKDITLAHKHLELVQQEANKGTL
                     HAMVTLSRLHGNKHDRTLFNMKLSARWAHFAFTLYPDNEIVMDCLDHLHFDSFWKRFR
                     FAWYTVRIPNSELPGQVNSMV"
     gene            4059..4778
                     /locus_tag="OPV72_004089"
     CDS             4059..4778
                     /locus_tag="OPV72_004089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000586683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HCR9916246.1"
                     /translation="MIIQRKSLFLCALLLLFATARAEITEQQIEADCAKIPVLASQGE
                     QLYKTQKYAKALDAFEQLAAWSESCALDDNAIATAYNNVALTWIREGEWRKARAWLML
                     RPNDSKSIYNLKLIKDKLSVLPPPVSTAGEYWRYAGRASWNVLSVKALPTPSRYQVNF
                     QGYWFGLMGIYFGPNIGEFYAEITLENDKAIVALREGDDIHCDISLAFSSETIDASTD
                     TFVDCGFGANVRADGHYLRVE"
BASE COUNT         1246 a         1316 c         1277 g         1187 t
ORIGIN      
        1 atgccagctt aattacacat ggatttttat gacagaaacg tcatctcacc gctataaacc
       61 acgcaatata ataaatgcgc caaatgtaaa atcatctatt ttttcccgga gccaacaacg
      121 cggcgatagc gaaaatatcc agcgctggtt aagcaatcat ttttatcgtt ggatcattgg
      181 tgactttcct cacgtttacc ctgtgcgctc cgtcgctgat tatgccgttt attttagccc
      241 tgatgcagaa atccccgcct gggtggcgat gagcgctttt actaccttaa cgttcagcac
      301 ccgcaacttg tggcaatgga aagagattta gtggaatttc tttcgcgtca ggaaggaacg
      361 cggctggaaa ctaaactaca gcgcatcaac tgctttaccg tgctggcaat gcgcgaagcg
      421 gagcatcaaa aaatgcagca cctgcgtgaa caaggttggt atccctccaa cagcgaggcg
      481 ctaaaaccgg tgatggcggt gaataacggt gtgctggttg agcttgatgc aacaaacccc
      541 ggcctgcgca gtgagatggc gtatgaatcc tggcatatgc aacactgcgt cggagatttt
      601 gataataaag gcgcgctttc cggcggctac ggcgattact acgcccggca aattgaacaa
      661 cagaaacttc gcctgttcag cctgcgcgac ggcaataata ttccccacgt cacaataagc
      721 ctggtggttg gtaataacgg cctgagcatt gatcagatta aaggtaagca aaatcgccat
      781 cctattaaga aatatgctaa cgatgtttta tctctgttac gccatctgca accacttcct
      841 gagcgccacg ctgattgcga agggatggga atagtttatg aatcgacgcc ggaatattca
      901 ggttggaaat ttattactca tattcatgac ctcaattttc tgctcaatgt gctgcatgac
      961 aattttcatt taatggaaca cttccccact cccccggtag ctttacagtg gctgctgctg
     1021 cacagcgccc cggaggcgct gcgctacctt caggttgttg atcctaacgt ggcgacggct
     1081 gcggaaatgc tgtttccacg gcatgaatgg caccctacgc ttgccgggaa aaacaccagt
     1141 agtgaacctt tcgaaattga aagcctgacg ctacaaacca cgcgttacct ccctgtcatc
     1201 aaggaggtgc aataatgttc tggattgttc ttattattgc cgccctattt tttagctggc
     1261 gcaactacaa aaaaaaacaa accgctgatt gcggcccgta tcgccgagga gaaagaaaaa
     1321 gatcgtctga aggatctgcg tcgcgatacc cgacggcggc aatgggcgct ggcgctagct
     1381 gatatcctcg cccggcgcaa cgggctaccg atcaaaggcg ttgagctggt cttcaaactt
     1441 gacgatgaca aacaccgcta tctggcacag caggtaaaaa aagagctggg cttgagcgaa
     1501 aacctcaacg gcgcggcgtt acgccacaag gtcgaggata tcttacgccg ctggcctgcg
     1561 ggcatcggca gctcgccgag cacgttttat catcatctgg cggcccaggg ccaggtccgc
     1621 gacgcgctgg ctttcgactg catgcgaacc gcctttctga cccgctgtat cgccgggctc
     1681 ggctggtgtg acgaaaacga ggcctggctg gtgttattac ttaacgccca gcgcgctcag
     1741 gactgttttg attcctggga ggattacgcc accgcctacg ttcgcgcccg ccgggtatgg
     1801 ctcacgctac gtgacacgcc aatagcgctt gccggacggg atttacagga agccacccat
     1861 tatctgcaag accctgtcag ccgctggcga caactgccgt ggaatgaatt caaaattttc
     1921 gagccgattt aaaggactat ttatggaaca ggatgatcgt ctgctcaacg ctatgtttga
     1981 gatgtgcaac cacaaaaatc ccctcaatga cgggcaacga gagtggcata tcgccgatat
     2041 tcccggcctg ctgcgcgaag aacgctatga cgaactggac gaacgctaca accaggcgct
     2101 gacggagagc tttaccagcc gcgaagcgga aaagcgctat ttcttcgcct ggaatcaaat
     2161 ggacaaccct ttttacgata tggacacgct ggttgaggct gggccgcaag gattagcgct
     2221 gatcaaaaac tggcagcgcg ctcgtccccg ctccactcac gcctggcttg ccgaggcgca
     2281 atactggaat caccgtgcgt ggctttaccg cagctatggc tgggcgagag aaaccacccg
     2341 agcgatgtgg atctgcgccg ccgcctgcaa cgaacggatg gtcatcgccg cgctcaatgc
     2401 tatcgactgt gaaccgcgcc agtggatggc ggcggccctg accagcacca actcaaaagt
     2461 cttcggccag cccgactggc tggttgagtt cctcgagggc gcggatgttg ccgggcagcc
     2521 attaatggaa gatctggctg aatatcatcg ccattcaccg caggaggtgg atgcgctgat
     2581 ggcccattcc gggctgtcgt ttgccgacgc ggtttgccca aatttgccgc gcccgtccgt
     2641 gctgccggag tgcaatgacg atgccgggca aaaatactgg ctcgccgtct gcctggctat
     2701 tttcccgacg gcattttacg tgctggatga atatatcccg tttcgtatgc cgcgctgggg
     2761 agggtctcac gaggaaatcc gcgaatttct ggaatcaagc gtatgcgatc acctttctgc
     2821 cgcagaacgt gaacatctgg agctattgat ctggtgggac gatcaccgcg atctgcgcat
     2881 caaagaggtt gactccccgg cagaacagga acgcattatc gccaaagccg aagagattag
     2941 cctgcgagcg catatccagg aatctcgcca caacacgctg aagtggctgc gggtctgcta
     3001 tagcgatctg gacgataatg acgcgctctg gcgaaccctt cagcgttcga tcgtggaaaa
     3061 agttaagttc aacaattact tctttgatga cacgataaag ttcgccctgc gcgattttcc
     3121 tgacacctgg tggatgtata attttctctg tcagaatgcg cagcaaacgg aattcgcagt
     3181 gccgaaaatc cgtcgtggct actttcagta cgccgggtta ttgggtttcg aaaaggatga
     3241 ggcgcaaggc ctcgcctggc tcgatagcgt cgccgacatt caatataacc ataactggcg
     3301 ggcggcgatt aaaaatttcg actggttcgg gctcccggaa cattttgtgc cgctggcaga
     3361 gctgggcgca caaagaaata tacccgccgc gctaaacctg ctgggccttg aacacaataa
     3421 taaagagaac aacggcctac taccttacga tcctgccatc gcgttagggt attttcagcg
     3481 cgcggcggag attttgcacc ggcggttagc gctgcgcgag agcaccccgt acaaattaat
     3541 agataacgga ggctataccg actatgaaaa tgacctgcaa aatattcatt tcagcatcgg
     3601 catctgcaac cagcgtctga gtaaacaaga acttgatacc gaaaaacgtt ccgcttatga
     3661 aaaagaactg ctcgataatc tctggctggc gcatcagttc gggcataaag aggcctgggg
     3721 cttgttcctg ctgaatattt ttgaagtgaa ggatattacg ctggcgcata agcatctgga
     3781 actggtgcaa caagaggcca acaaaggcac gctacacgct atggtgaccc tatcgcgcct
     3841 gcacggtaat aaacacgatc gaacgctgtt taatatgaag ctaagcgcac gctgggcaca
     3901 ttttgccttc acgctttacc cggataatga aatcgttatg gattgcctgg accacctgca
     3961 tttcgattct ttctggaaac gctttcgttt cgcctggtat accgtccgta tcccgaattc
     4021 agagctgccg ggacaggtca actcaatggt gtaatggagt gataatacaa agaaaatctc
     4081 tatttctttg cgccctgctt ctactcttcg ccaccgccag ggctgaaatt acggagcagc
     4141 agatcgaggc cgactgcgca aaaattccag ttttggccag ccagggcgaa cagctttaca
     4201 agacccaaaa gtatgccaaa gcactcgacg cttttgaaca gctggccgca tggagcgaaa
     4261 gctgcgccct tgacgacaac gccatcgcga cggcctacaa caacgtggcg ctaacctgga
     4321 tacgcgaagg cgagtggcgt aaagcccgcg cctggctgat gctaaggccg aatgatagca
     4381 agtcgatcta caacctgaaa ctgatcaaag ataagctatc ggtcctgccg ccaccggttt
     4441 ccacggcggg tgaatactgg cgctatgccg ggcgcgcctc ctggaacgtg cttagcgtga
     4501 aggcattacc caccccatcg cgctatcagg ttaattttca gggttactgg ttcggtttaa
     4561 tggggatcta cttcggcccc aatatcggcg agttctacgc agagataacg ctggaaaacg
     4621 ataaagccat cgtggcgctt cgggaaggcg atgatattca ctgtgacatt tcgctggctt
     4681 tttcttctga aaccattgat gccagcactg atacgtttgt ggactgcggt tttggcgcaa
     4741 atgtccgcgc cgacgggcac tatctgcgcg ttgaataaat ctggcgcgga aactgaaatt
     4801 ttatgattaa cctgagatca gttgaaatta acaatctatt tataatttcc ataacgttcc
     4861 tcattctttc ctgctatcca tattatctta acacctccat tacaattatt aatgtcgtaa
     4921 gcatggtata tttaacgctc gcttcttttt tcaccctgtg atactgcatt tctggatatc
     4981 aatttgaatc gaccattttc catttgatat tgttccttta tataaa
//
LOCUS       DAJVBX010000244         5015 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.244, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000244 DAJVBX010000000
VERSION     DAJVBX010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 5015)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5015)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5015
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.244"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(117..788)
                     /gene="queE"
                     /locus_tag="OPV72_004090"
     CDS             complement(117..788)
                     /gene="queE"
                     /locus_tag="OPV72_004090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-carboxy-7-deazaguanine synthase QueE"
                     /protein_id="HCR9916247.1"
                     /translation="MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTW
                     DKLSDREVSLFSILAKTKESDKWGAASSEDLLAVINRQGYTARHVVITGGEPCIHDLM
                     PLTDLLEKSGFSCQIETSGTHEVRCTPNTWVTVSPKVNMRGGYDVLSQALERANEIKH
                     PVGRVRDIEALDELLATLSDDKPRVIALQPISQKEDATRLCIETCIARNWRLSMQTHK
                     YLNIA"
     gene            complement(924..2222)
                     /gene="eno"
                     /locus_tag="OPV72_004091"
     CDS             complement(924..2222)
                     /gene="eno"
                     /locus_tag="OPV72_004091"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020456663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HCR9916248.1"
                     /translation="MSKIVKVIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTG
                     SREALELRDGDKSRFLGKGVTKAVGAVNGPIAQAILGKDAKDQAGIDKIMIDLDGTEN
                     KSNFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHA
                     DNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKGKGMNTAVGDEGGYAPNLGS
                     NAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHF
                     LEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKG
                     IANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQI
                     KTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA"
     gene            complement(2305..3942)
                     /gene="pyrG"
                     /locus_tag="OPV72_004092"
     CDS             complement(2305..3942)
                     /gene="pyrG"
                     /locus_tag="OPV72_004092"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase (glutamine hydrolyzing)"
                     /protein_id="HCR9916249.1"
                     /translation="MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPY
                     INVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRK
                     ERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQL
                     AVDIGREHALFMHLTLVPYLAAAGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPA
                     NERAKIALFCNVPEKAVISMKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEW
                     EQVIYEEANPAGEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVTVNIKLIDSQDVE
                     TRGVEILKDLDAILIPGGFGYRGVEGKIATARYARENNIPYLGICLGMQVALIEFARN
                     VAGMDNANSTEFVPDCKYPVVALITEWRDEDGNVEVRSEKSDLGGTMRLGAQQCQLSD
                     DSLVRQLYGASTIVERHRHRYEVNNMLLKQIEAAGLRVAGRSGDDQLVEIIEVPNHPW
                     FVACQFHPEFTSTPRDGHPLFAGFVKAANEHQKRQAK"
     gene            complement(4170..4970)
                     /gene="mazG"
                     /locus_tag="OPV72_004093"
     CDS             complement(4170..4970)
                     /gene="mazG"
                     /locus_tag="OPV72_004093"
                     /EC_number="3.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphohydrolase"
                     /protein_id="HCR9916250.1"
                     /translation="MTTNHQIDRLLTLMQRLRDPENGCPWDKEQTFASIAPYTLEETY
                     EVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHV
                     FGELSADNSEEALVRWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCSNVGF
                     DWTTLGPVVDKVYEEIDEVMFEARQAVVDQAKLEEEMGDLLFATVNMARHLGTKAEIA
                     LQKANDKFERRFREVERIVAARGLEMTGVDLETMEEVWQEVKRQEIDL"
BASE COUNT         1184 a         1353 c         1212 g         1266 t
ORIGIN      
        1 aaatttatca gcgcttttat acactcatcg aaattcacat agagaaaata aacaatgcaa
       61 ggtaatggat gagtcacaga cggcaacggc aggccgtccg taagattaat aatgcctcag
      121 gcgatattta aatatttatg cgtttgcata gacagccgcc agttacgcgc aatacacgtt
      181 tcaatacaca gacgcgtcgc gtcttctttc tggctaatgg gctgcaaagc aatcacgcgc
      241 ggtttatcat cgctcaacgt ggctaacagt tcatccagcg cctcaatatc acgaactcgc
      301 ccaacgggat gcttgatttc attggcgcgc tccagcgcct gggaaagcac gtcatatccc
      361 ccgcgcatat tcacttttgg tgaaaccgtg acccaggtat tgggcgtaca gcgcacttcg
      421 tgcgtcccgc tggtttcaat ctggcaacta aaaccactct tttcaagcag atcggtgagc
      481 ggcatgaggt cgtgaataca gggttcgcca ccggtgatga caacgtgacg cgcggtatag
      541 ccctgacgat taattactgc cagcaagtct tcactgctcg cagcacccca tttgtcgctc
      601 tctttggttt ttgccagaat gctgaacaga gacacttccc gatcgctcag tttatcccag
      661 gtatgcttag tatcacacca ggcacagccg accggacatc cctgtaaacg aataaaaata
      721 gcggggacgc cggtaaaata accctcgcct tgtagggtct ggaacatctc gttaatcggg
      781 tactgcatag cgttctctgt taaggggata atcgttaatt attgcagatt tcgtctgccc
      841 ggtcatgcac agcggctgcg ctattgaaca gatacaaaaa aacccgccga agcgggttta
      901 tacgttaaga ggtaaaagca ggattacgcc tggcctttga tctctttacg accgttgtac
      961 ggtgcttttt cgcccagagc ttcttcgata cgaatcagct ggttgtattt agcaacacgg
     1021 tcagaacggc tcatagaacc ggttttgatc tggcctgcag cggtaccaac agccaggtca
     1081 gcaatggtag cgtcttcagt ttcaccagaa cggtgagaga tgacagcagt gtagccagcg
     1141 tctttcgcca tcttgattgc agccagagtt tcggtcagag aaccgatctg gttgaatttg
     1201 atcaggatgg agttagcgat gcctttctcg atgccttctt tcaggatttt ggtgttggtt
     1261 acgaacaggt cgtcaccaac cagctggatt ttgtcgccca gtactttggt ctggtatgca
     1321 aaaccgtccc agtcagactc gtccagacca tcttcgatgg aaacgatcgg gtactgtttg
     1381 gtcagttctt ccaggaagtg ggtgaattct tcggaggtga atgctttgtt gccttcgcca
     1441 gccagaacgt atttaccgtc tttgtagaat tcagatgctg cgcagtccat cgccagggtg
     1501 atgtctttac ccagctcgta accagccgct ttaaccgctt cagcgataac agccagcgct
     1561 tcagcgttgg aacccaggtt cggcgcatag ccgccttcgt cacccacagc ggtgttcatg
     1621 cctttgcctt tcagcacttt tgccaggtga tggaaaactt cagaacccat acggatggct
     1681 tctttaaccg ttttcgcgcc aaccggctgg atcatgaatt cctggatgtc gacgttgttg
     1741 tcagcgtgct cgccgccgtt gatgatgttc atcatcggaa ccggcatgga gtatttgccc
     1801 ggcgtgccgt tcagttcagc aatgtgctcg tacagcggca tacctttagc ggcagcagca
     1861 gctttggcgt tagccagaga gacagccaga atggcgtttg caccgaagtt agatttgttt
     1921 tcagtaccgt ccaggtcgat catgattttg tcgatgccag cctggtcttt agcgtctttg
     1981 ccaagaatag cctgagcgat cgggccgtta accgcgccaa cagctttggt tacgccttta
     2041 cccaggaaac gggatttgtc gccatcgcgc agttccagcg cttcgcggga accagtagaa
     2101 gcacctgacg gagccgccgc catacctacg aaaccacctt ccaggtgtac ttcagcttca
     2161 acagtcgggt taccacggga gtcgatgatt tcacgaccga tgactttaac gattttggac
     2221 attaggtttt cctcaagtca ctagttaaac taaaacttca gacaaacggt gcaccgctga
     2281 gggtgcaccg ccgttctaac ttttttactt cgcctgacgt ttctgatgct cgttggcggc
     2341 tttaacaaag ccggcgaaca acggatgtcc atcacgcggc gtggaagtaa attccggatg
     2401 gaactgacag gccacgaacc acggatgatt cggtacctca atgatctcga ctaactgatc
     2461 atcaccggaa cggcctgcga cacgcagacc cgctgcttca atttgtttca acaacatatt
     2521 gttgacttcg taacgatggc gatgacgttc aacaatcgtc gacgcgccgt acaactgacg
     2581 taccaggctg tcatcgctaa gctggcactg ctgcgcgccc aggcgcatgg tgccgcccag
     2641 atcgcttttc tcgctacgga cttcaacgtt accgtcttca tcgcgccact cggtaattaa
     2701 cgccacaacc gggtacttac agtctggcac aaattccgtt gagttggcgt tgtccatgcc
     2761 ggccacgtta cgagcgaact caatcaacgc aacctgcatc cccaggcaaa tgcccagata
     2821 aggaatattg ttttcacgcg catagcgcgc agtggcgatt ttaccttcaa cgccacgata
     2881 gccgaagccg ccggggatca ggatagcgtc caaatctttc agaatttcga cgccgcgcgt
     2941 ttcaacatct tgcgaatcga tcaatttgat gttgacggta acgcggtttt tcagaccacc
     3001 gtgtttcagc gcttcgatca ccgacttata ggcatccggc agttcaatat atttgccgac
     3061 catgccgata gtcacttcgc ctgccgggtt cgcttcttcg taaatgacct gttcccattc
     3121 agacaggtta gcttccggac agttcaagct gaatcgttta caaatataat catcaagccc
     3181 ctgagatttc aacaggcctg gaattttata aatggaatcg acatctttca ttgaaataac
     3241 ggctttttcc ggcacattac agaacaatgc aatttttgca cgctcgttgg caggaaccgc
     3301 acggtcggaa cgacaaatca gaatatcggg ctgaataccg atagacagca gctctttcac
     3361 ggagtgctga gtcggtttag ttttcacttc gcccgcagcc gccaggtaag gtaccagcgt
     3421 caggtgcata aacagcgcgt gttcacgacc gatatctacc gccaattgac gaatcgcctc
     3481 aagaaacggc agcgattcga tatcaccgac ggtaccgccg atttccacca gcaccacatc
     3541 gtggccttcg ccaccttcca gcacgcgctc tttaatcgcg ttagtgatgt gagggatgac
     3601 ctgtacggtt gcgcccagat agtcgccacg gcgttcttta cgcagaacgt cggagtagat
     3661 acggccagtc gtgaagttgt tgcggcgaga catcttggtg cggatgaaac gctcgtagtg
     3721 ccccaggtcc aggtcggttt cagcgccgtc ttcagtaacg aacacttccc cgtgttggat
     3781 tgggctcata gtacccggat cgacgttgat gtacggatcc agtttcatga tggtcacgtt
     3841 gagaccacgg gcttccagaa tggctgcgag ggaggctgcg gcaatgcctt tacccagaga
     3901 ggatacgacc ccgccggtca caaaaatata gttcgttgtc atgcggaacc tgagaagtta
     3961 ggtttaaaag acgatggaat aaccaggacg ggaaagcagt atacccgaac atgacctacg
     4021 ccacaaactt tcattattcc tcctcttcgc caggctgaca ttcacacagg gagggagaaa
     4081 atagcccctt tgaggtaaat gtttttgacg taaatcaagc gcttgttatt taaaaaatca
     4141 cacaaatcgc tcttgaccgc ctaaaacctt tagagatcaa tttcctggcg ttttacttcc
     4201 tgccaaactt cttccattgt ttccaggtct accccggtca tttccaggcc tctggctgcg
     4261 acaatacgtt caacttcgcg aaaacgacgt tcaaatttat cgttcgcttt ttgcaaagcg
     4321 atctccgctt tcgtacctaa atgacgcgcc atgttgaccg tggcaaagag caaatcgccc
     4381 atttcctctt ccagtttagc ctgatcaaca accgcctgcc gcgcctcgaa catcacctca
     4441 tcgatctctt catagacctt atcgacgacc ggccccagcg tcgtccagtc gaagcccacg
     4501 tttgaacacc gtttctggat tttttgcgcg cgcattaagg ccggtaagct gcgcggaata
     4561 tcgtccagcg cggaatgctg cgctttttgc gcgcgctctt ccgttttgat ttgctcccag
     4621 cgaactaatg cttcttcgct attatccgcg gaaagctcgc caaaaacatg cggatggcgg
     4681 cgctccagct tgtcgctgat ggcagcgcaa atatcattaa aatcgaagcg gccttcttcc
     4741 tgcgccatct gcgcgtaaaa caccacctgg aacaacaggt cgcccagttc gccgcgcaaa
     4801 tcgtcaaaat cctcacgcgc aatcgcatcc agtacttcat aggtttcttc cagtgtataa
     4861 ggcgcgatgc tggcgaaggt ctgctcttta tcccacgggc agccgttttc cgggtcgcgc
     4921 aggcgctgca tgagggtgag aagacggtca atttgatggt tagttgtcat ggtctttaat
     4981 cggttgtaaa tactagcgac aattgtaacg tatta
//
LOCUS       DAJVBX010000245         4987 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.245, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000245 DAJVBX010000000
VERSION     DAJVBX010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4987)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4987)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4987
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.245"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..953
                     /locus_tag="OPV72_004094"
     CDS             <1..953
                     /locus_tag="OPV72_004094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator"
                     /protein_id="HCR9916251.1"
                     /translation="SDNNQAERQPADQHLQDKPQIFRTLRNIDLNLLTIFEAVYVHKG
                     IVNAAKILNLTPSAISQSIQKLRTIFPDPLFIRKGQGVTPTTYATHLHEYISQGLESI
                     LGALDLTGSYDKQRTITIGTTPSVGALVMPIIYQAIRPRYPQLLLRNIPVDDAESQLS
                     QFQTDLIINTHSYNNRSIQHHVLFSDTLEIVCRQHHPCLANAITEERLNSADHTFLML
                     EGQHLSLLRQRLQETFPDQQISFSSYNIFTIASLIASSDLLGLMPTRFYDLFSRCWPL
                     ERLPYAPVNSEQVEFSLHYNKLSLRDPVLENVIDIIREAF"
     gene            1159..2124
                     /gene="lipA"
                     /locus_tag="OPV72_004095"
     CDS             1159..2124
                     /gene="lipA"
                     /locus_tag="OPV72_004095"
                     /EC_number="2.8.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoyl synthase"
                     /protein_id="HCR9916252.1"
                     /translation="MSKPIVMERGVKYRDADKMALIPVKNVVTERDALLRKPEWMKIK
                     LPADSTRIQGIKAAMRKNGLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCD
                     VAHGRPVAPDAEEPQKLAQTIADMALRYVVITSVDRDDLRDGGAQHFADCITAIRAKS
                     PEIKIETLVPDFRGRMDRALDILNATPPDVFNHNLENVPRIYRQVRPGADYNWSLKLL
                     ERFKEAHPEIPTKSGLMVGLGETNAEIIEVMRDLRRHGVTMLTLGQYLQPSRHHLPVQ
                     RYVSPEEFDEMKAEALAMGFTHAACGPFVRSSYHADLQAKGMEVK"
     gene            complement(2211..2414)
                     /gene="tatE"
                     /locus_tag="OPV72_004096"
     CDS             complement(2211..2414)
                     /gene="tatE"
                     /locus_tag="OPV72_004096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="twin-arginine translocase subunit TatE"
                     /protein_id="HCR9916253.1"
                     /translation="MGEISITKLLVVAALVVLLFGTKKLRTLGGDLGTAIKGFKKAMN
                     DEDAGVKKDVDGSVQAEKLSHKE"
     gene            complement(2542..3329)
                     /locus_tag="OPV72_004097"
                     /pseudo
     CDS             complement(2542..3329)
                     /locus_tag="OPV72_004097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003022696.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="deaminated glutathione amidase"
     gene            3420..3803
                     /gene="crcB"
                     /locus_tag="OPV72_004098"
     CDS             3420..3803
                     /gene="crcB"
                     /locus_tag="OPV72_004098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HCR9916254.1"
                     /translation="MLQLLLAVFIGGGTGSVARWMLSMRFNPLHQAIPIGTLTANLLG
                     AFIIGMGFAWFNRMTHIDPMWKVLITTGFCGGLTTFSTFSAEVVFLLQEGRFGWALLN
                     VLINLLGSFAMTALAFWLFSAAAAR"
     gene            complement(3861..4070)
                     /gene="cspE"
                     /locus_tag="OPV72_004099"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
     CDS             complement(3861..4070)
                     /gene="cspE"
                     /locus_tag="OPV72_004099"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator/RNA stability
                     regulator CspE"
                     /protein_id="HCR9916255.1"
                     /translation="MSKIKGNVKWFNESKGFGFITPEDGSKDVFVHFSAIQTNGFKTL
                     AEGQRVEFEITNGAKGPSAANVTAL"
     gene            complement(4258..4830)
                     /gene="pagP"
                     /locus_tag="OPV72_004100"
     CDS             complement(4258..4830)
                     /gene="pagP"
                     /locus_tag="OPV72_004100"
                     /EC_number="2.3.1.251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid IV(A) palmitoyltransferase PagP"
                     /protein_id="HCR9916256.1"
                     /translation="MYVAMIIRKYFLIIALLVMPWLAIPSVSAADKGWFNTFTDNVAE
                     TWRQPEYYDLYVPAITWHARFAYDKEKTDRYNERPWGVGFGQSRWDDKGNWHGLYMMA
                     FKDSFNKWEPIGGYGWEKTWRPLEDDNFRLGLGFTAGVTARDNWNYIPIPVLLPLASI
                     GYGPATFQMTYIPGSYNNGNVYFAWMRFQF"
BASE COUNT         1295 a         1350 c         1141 g         1201 t
ORIGIN      
        1 tgagtgataa taatcaggca gaaagacaac cggccgatca acacctacaa gacaaaccgc
       61 aaattttcag aacactgaga aatattgacc tcaatctgtt gacgattttc gaggccgtat
      121 atgtccataa agggatcgtc aatgcagcga aaattcttaa cctgacgccg tcagccatca
      181 gccagtccat tcaaaaatta cggactatat ttcccgatcc gctgtttatt cgcaaaggcc
      241 agggcgtaac gcccacgacg tatgctacgc atctgcacga atacatcagc caggggctgg
      301 aatctattct tggcgccctg gatcttacgg gcagctatga taagcaacgc accattacaa
      361 ttggcacgac accttcggtc ggcgcgctag tgatgccgat tatttaccag gccatcaggc
      421 cgcgttatcc tcagcttttg ctgcgcaaca ttccggtaga cgatgccgaa agccagctta
      481 gtcagtttca gaccgatctc attatcaata cccatagcta taacaaccgg agcatccagc
      541 atcacgtcct gtttagcgat acgcttgaga ttgtctgccg ccagcatcac ccgtgtctgg
      601 cgaacgccat tactgaagag agactgaaca gcgcggatca cacctttctg atgctggagg
      661 gacaacatct ttccctcctg cgccagcgac tgcaggagac atttcccgat cagcaaatca
      721 gttttagcag ctacaatatt tttaccattg cctcgctgat cgccagcagc gatctgctgg
      781 gactgatgcc cacccgcttc tacgacttat ttagccgttg ctggccgctt gaacgccttc
      841 cctacgcgcc ggtgaatagt gaacaggtcg agttctcgct gcattacaat aaactgagtc
      901 tgcgcgatcc ggtgctggag aacgtcattg atatcatccg tgaggcgttc tgacaaaaat
      961 gttgcattca ggtcacggaa gatatgggca aacagcacaa aacaacaact attttacatt
     1021 ttgccgggct gtcaggctgc tttatggccc ttatcaatga tatactgcgt gtcacaaatt
     1081 caaaaatagt tgataaatac aactttccct tgaattgaaa cgctttcctt cgttattcgc
     1141 aactggaaca cgcacgctat gagtaaaccc attgtgatgg aacgcggtgt aaaataccgc
     1201 gatgccgata agatggctct tatcccggtt aaaaatgtgg tcacagagcg cgacgctcta
     1261 ctacgtaaac cggaatggat gaaaataaaa cttccggcgg attctacccg tatccaaggc
     1321 atcaaagccg caatgcgcaa aaatggcctg cattctgtct gtgaggaagc gtcttgccca
     1381 aacctggctg aatgtttcaa ccacggtacc gctacgttta tgatccttgg cgccatttgc
     1441 actcgccgct gtccgttctg tgatgtcgcc catggccgcc ccgttgcgcc ggatgcggaa
     1501 gagccgcaga aactggcgca aacgatcgcc gacatggcgc tacgctatgt ggtcatcacc
     1561 tctgtcgacc gtgacgatct gcgtgacggc ggcgcccagc actttgctga ctgcatcacc
     1621 gccatccgcg ccaaaagccc ggagataaaa atagagaccc tggtgccaga cttccgtgga
     1681 cgtatggatc gcgcgctgga tattcttaac gcgacgccgc cggatgtgtt taaccacaac
     1741 ctggaaaacg tgccgcgtat ttaccgccag gttcgtccgg gcgccgatta caactggtcg
     1801 ctgaaattac tggaacgctt caaagaagcg cacccggaaa ttccgacaaa atcgggtctg
     1861 atggtgggct taggcgaaac caatgcggaa atcattgagg ttatgcgcga cttacgccgt
     1921 cacggcgtta ccatgctgac gcttggtcag tatctacagc caagccgcca tcacctgccg
     1981 gtacagcgtt atgtcagccc ggaagagttt gacgagatga aagcagaagc cctggcgatg
     2041 ggctttaccc atgccgcctg tggccccttt gtacgttctt cgtaccatgc tgatctccag
     2101 gccaaaggca tggaagtgaa atgatcgtgt aatagacgct tacatttcag gcaaaaaaaa
     2161 accggcaact cgccggtttt tttactctgc ggagcaagcg cattgcgcta ttactcttta
     2221 tgcgagagtt tttcagcctg aacgctaccg tcgacgtctt tcttaacgcc cgcgtcttca
     2281 tcgttcattg ctttcttgaa tcctttaatc gccgtgccca agtctccgcc cagcgtacgt
     2341 aacttcttgg taccaaacag cagaacaacc agtgcggcaa ccaccagcag tttggtaata
     2401 ctaatctcac ccatagatac cttcttcact aaaaacaggc tgcgtaacgc gccggattaa
     2461 cctgagaata ttaacggtct ttcgacgcgc gcacacaata gcaatctgta acaaggtgaa
     2521 tcaagctttg cgtaaaaaac atcataataa ttgcggtggc gcaaatcgtc gttgctgcaa
     2581 aagaggaagt tgctcccgca cctggtctat tcgttctctg aatatttccg cgacgatcag
     2641 cgccggacga tcggctgccg cggctatcgt tacccccaac ggtcgataat acgactttga
     2701 ccaatattac gattaccaca ctccccggcc gcaatcatat agcaggtggt atccagcgct
     2761 ctcgccgcca gcagcgtcga ccactgctgc tctttcaacg ggccgcgaac ccagcccgtc
     2821 ggcagcgcca atacgtcagc cccctgtaaa gccagcgcta acgccatatc cggaaagcgc
     2881 aggtcataac aggtcataag acccacctta accccctcca cgtccagcac aggcgcgata
     2941 acggttccgg catcaatact ttgggattct tgcatcgaaa acgcatcata gagatgcagc
     3001 ttcgcgtaac gcgcgacaat gtgacccgcc cgtagcgcca ccagcatatt aaccgcccgt
     3061 ccaggcgttg acgggacaag gatagtgaat atcgtcgtca tattattatg agcgctttct
     3121 tccagaagcc gcgtcataaa cgcgccatcc agcggctgcg cggcgcgaat cggcaggtca
     3181 aggtcgatgt catctcgcgc taatatcccc tcaggcaaca ccagaagcga tacgccgcgg
     3241 cccgccgcct gagccattaa cgaaacgcaa acttgcacat tctcttccca tacagaactc
     3301 accacaaact gcccggctgc aacgaacata tcccctccca cacctctgtc aggactcgcc
     3361 aattatgcgt gttcggcgtt acactcctct tgtatagcaa ttaaataaag gattcggcag
     3421 tgttacagct tcttttagca gtttttattg gcggtggaac ggggagcgta gcccggtgga
     3481 tgctcagtat gcgttttaat ccgcttcatc aggcgattcc catcggtacg ctaacagcaa
     3541 atttacttgg cgcgtttatt atcggcatgg ggttcgcctg gtttaaccgc atgacacata
     3601 tcgatccgat gtggaaagtg ctcattacga ccggcttttg cggcggcctg acgacctttt
     3661 ctactttttc tgccgaagtg gtattcttgc tgcaagaggg gcgctttggc tgggcgctgc
     3721 tgaatgtgct gattaacctg ttgggttcgt ttgccatgac ggcgctggca ttctggctat
     3781 tttccgccgc cgcagcgcgt taagcgcaaa aaaaacccgc cgaaagggcg ggttttgaaa
     3841 tcttgctgtc ggacgtatgc ttacagagca gttacgtttg cagcggaagg gcctttggca
     3901 ccgttagtga tttcgaactc tacgcgctga ccttcagcca gagttttaaa accattggtc
     3961 tggattgcag agaagtgtac aaacacgtct ttgctgccat cttccggagt aatgaaaccg
     4021 aatcctttgg attcattaaa ccacttaacg ttacctttaa tcttagacat caaaattacc
     4081 tttacatgaa aaatagacac aaatgctgta tcggatacca gtacaacaat tgtgatgcat
     4141 tttgtccagt cgaactttgc gaaaaagtga taaatatcgc gttaattttt agctaaccct
     4201 atctacttat tgttttttaa ggctttttaa ttcacaacag aacaatgccc ttctccgtca
     4261 aaactggaaa cgcatccagg caaaatagac gtttccgttg ttatacgaac ccggaatgta
     4321 ggtcatctga aaggtagcgg gaccatagcc tatcgacgct aaaggcaaca gcacagggat
     4381 gggaatataa ttccagttgt cgcgcgcggt aacgcctgcg gtaaagccca gtcccagacg
     4441 aaaattatcg tcttccagcg gtcgccaggt tttttcccag ccataaccgc ctatgggttc
     4501 ccatttgtta aatgaatctt taaaggccat catatagagg ccatgccagt tgcctttatc
     4561 gtcccagcgc gactgaccaa aaccaacgcc ccacggccgt tcgttatagc gatccgtttt
     4621 ctctttatcg taggcaaagc gcgcatgcca ggtaatggcg gggacataca aatcataata
     4681 ctcaggctgt cgccacgttt ctgcgacgtt atcggtaaac gtgttaaacc accctttatc
     4741 cgccgcagag actgaaggaa tagccagcca tggcataaca aggagagcaa taataagaaa
     4801 atactttctg atgatcatcg caacatacat accgttcaaa aattcgactg tgataataac
     4861 aacattaacc tgaataaaat cttaacaaac tataaacaga gaataatctg agagagtatc
     4921 gggttaacgg cgtttgattt agcactcaga accgtcacgc gctccttaat aagctttcac
     4981 aaaaaac
//
LOCUS       DAJVBX010000246         4951 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.246, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000246 DAJVBX010000000
VERSION     DAJVBX010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4951)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4951)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4951
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.246"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            17..447
                     /locus_tag="OPV72_004101"
                     /pseudo
     CDS             17..447
                     /locus_tag="OPV72_004101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000401539.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(510..2942)
                     /gene="metL"
                     /locus_tag="OPV72_004102"
     CDS             complement(510..2942)
                     /gene="metL"
                     /locus_tag="OPV72_004102"
                     /EC_number="1.1.1.3"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000110794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aspartate kinase/homoserine
                     dehydrogenase II"
                     /protein_id="HCR9916257.1"
                     /translation="MSVIAQAGAKGRQLHKFGGSSLADVKCYLRVAGIMAEYSQPDDM
                     MVVSAAGSTTNQLISWLKLSQTDRLSAHQVLQTLRRYQCDLISGLLPADAADDLTSAF
                     ISDLERLAALLDGGVTDAVYAEIVGHGEIWSARLMSAVLNQQGLDAAWLDARAFLRAE
                     RAAQPQVDEGLSYPLLQQLLAQHPGKRLVVTGFISRNHDGETVLLGRNGSDYSATQIG
                     ALAGVSRVTIWSDVAGVYSADPRKVKDACLLPLLRLDEASELARLAAPVLHARTLQPV
                     SGSDIDLQLRCSYTPDQGSTRIERVLASGTGARIVTSHDDICLIEFQVPASQDFRLAH
                     KELDQILKRAQARPLAVGVHRDRQLLQFCYTAEVADSVLKLLDDVGLPGELRLRQGLA
                     LVAMVGAGVTRNPLHCHRFWQQLKGQPVEFTWQSEEGISLVAVLRTGPTESLIQGLHQ
                     SVFRAEKRIGLMLFGKGNIGSRWLELFAREQSTLSARTGFEFVLAGVVDSRRSLLNYE
                     GLDASRALAFFDDEAVEQDEESLFLWMRAHPYDDLVVLDVTASEQLADQYLDFASHGF
                     HVISANKLAGASASDKYRQIHDAFEKTGRYWLYNATVGAGLPINHTVRDLIDSGDTIL
                     SISGIFSGTLSWLFLQFDGTVPFTDLVDQAWQQGLTEPDPRVDLSGKDVMRKLVILAR
                     EAGYDIEPDQVRVESLVPAHCEEGSIDHFFENGDALNEQMVQRLEAARELGLVLRYVA
                     RFDANGKARVGVEAVRPEHPLAALLPCDNVFAIESRWYRDNPLVIRGPGAGRDVTAGA
                     IQSDINRLAQLL"
     gene            complement(2945..4105)
                     /gene="metB"
                     /locus_tag="OPV72_004103"
     CDS             complement(2945..4105)
                     /gene="metB"
                     /locus_tag="OPV72_004103"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HCR9916258.1"
                     /translation="MTRKQATIAVRSGLNDDEQYGCVVPPIHLSSTYNFTGFNEPRAH
                     DYSRRGNPTRDVVQRALAELEGGAGAVLTNTGMSAIHLVTTVFLKPGDLLVAPHDCYG
                     GSYRLFDSLATRGCYRVRFVDQGDERALQAALEEKPKLVLVESPSNPLLRVVDIAKIC
                     RLAREAGAVSVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVMIAKDPEM
                     VTELAWWANNIGVTGGAFDSYLLLRGLRTLVPRMELAQRNAQAIVKYLQTQPLVKKLY
                     HPSLPNNQGHEIAARQQKGFGAMLSFELDGDEETLRRFLGGLSLFTLAESLGGVESLI
                     SHAATMTHAGMSPQARAAAGISETLLRISTGIEDGEDLIADLENGFRAANKG"
     gene            4370..4687
                     /gene="metJ"
                     /locus_tag="OPV72_004104"
     CDS             4370..4687
                     /gene="metJ"
                     /locus_tag="OPV72_004104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015855437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="met regulon transcriptional regulator MetJ"
                     /protein_id="HCR9916259.1"
                     /translation="MAEWSGEYISPYAEHGKKSEQVKKITVSIPLKVLKILTDERTRR
                     QVNNLRHATNSELLCEAFLHAFTGQPLPDDADLRKERSDEIPEAAKEIMREMGIDPET
                     WEY"
BASE COUNT         1175 a         1473 c         1246 g         1057 t
ORIGIN      
        1 aaaacaaggg ataaatatgg aaattacttt accgtcaatg tcagataaaa aatggacctg
       61 cgccgatctc ctgagtagct accgattctg ggggatcact tttttctttt tggcgctctc
      121 ttttatcagt tcgctgggat cgtcgtatgg tgtttatttt tggagtaaat cactgtctat
      181 tccagccgat cgtattggtc ttattctcgt tggcgtaaat ggcccatctg acgtagtcag
      241 gcttatcata gcacagcaat attgtgtctg acgcttagcg acgaaatcca aacattgcgg
      301 gcgaatgcaa acgaaaatac aggtatacag agcggctgga cgctattttg ggcattgctg
      361 ttcccccctg tcggcatagc cattatccag gcgaagatga accgatttat cgtcgccaat
      421 gcagaaaacg catctgacga agaataaaca gataccccgg tttgcccgct gccggatctg
      481 gcgaagccgc tatccggcag gcgggcgtat tacaatagct gcgccaggcg gttgatatcc
      541 gactgaatcg ccccggcggt cacatcgcga cccgcgcccg gcccacggat caccagcggg
      601 ttatcgcgat accagcggct ttcaatagca aagacattat cgcacggcag cagcgccgcc
      661 agcggatgct ccggacgcac cgcttcaacg ccgacgcgcg ctttgccatt ggcgtcgaaa
      721 cgcgccacgt aacgcaacac cagccccagt tcgcgggctg cctccagacg ctgcaccatc
      781 tgttcattca gcgcgtcgcc gttttcgaaa aagtgatcga tagacccttc ttcacagtgc
      841 gccggcacca acgattctac acgcacctga tccggctcga tgtcgtatcc cgcctcgcgc
      901 gccagaatca ccagcttacg catgacatct tttccggaaa gatcgacgcg cggatcgggt
      961 tccgtcagcc cctgctgcca ggcctgatcc accagatcgg taaacggcac cgtgccgtca
     1021 aattgcagga acagccagga tagcgtcccg gagaagatcc cgctgatcga gagaatcgta
     1081 tcgccgctgt caatcagatc ccgcaccgtg tggttgatcg gcaaccccgc gcccacggtg
     1141 gcgttataca gccagtaacg cccggttttt tcaaacgcgt catgaatctg gcgatactta
     1201 tcgctggcgc ttgcgcccgc cagtttattg gcgctaatca catgaaaacc gtggctggcg
     1261 aaatcaaggt actgatcggc cagttgctcg cttgctgtca catccagcac cactaaatca
     1321 tcatacggat gcgcacgcat ccacaggaat agcgactctt cgtcctgctc aacggcttca
     1381 tcatcaaaga atgccagcgc gcggctggcg tccagccctt cataattcaa caggctacgg
     1441 cggctatcca ccacgcccgc cagcacaaat tcaaaaccag tacgcgcgga aagcgtgctt
     1501 tgttcacggg caaatagttc cagccaacgg gagccgatgt tccccttacc gaacagcatc
     1561 aggccaatgc gtttttcggc gcggaaaaca gactggtgca gcccctgaat caggctctca
     1621 gtcgggccgg tacgcagcac cgccaccaga ctgatgccct cctccgactg ccaggtaaac
     1681 tccactggct gacctttcaa ctgctgccag aagcgatggc agtgtagcgg attgcgagtg
     1741 acgcccgcac cgaccatcgc caccagcgcc agcccctgcc gcaggcgcaa ttcgcccggc
     1801 agtccgacat cgtcgaggag tttcagtacg ctatccgcta cctcggcggt atagcagaac
     1861 tgcaatagct ggcgatcgcg atgcacgccc accgccagcg gacgcgcctg cgcccgtttt
     1921 aaaatttggt cgagctcttt gtgcgccagc ctgaaatcct ggctggcggg cacctgaaac
     1981 tcaatcagac agatatcatc gtgactggtc acgatacgcg cgcccgtccc ggaagccagc
     2041 actcgttcaa ttcgggttga cccttgatcc ggcgtgtagc tacagcgcaa ctgcaaatcg
     2101 atatcgctgc cggacactgg ctgtagcgtg cgggcgtgca gaacaggcgc cgccagacgc
     2161 gccagctcgc tggcttcgtc cagacgcagc aacggcagca ggcaggcatc tttcactttg
     2221 cgcgggtcgg cgctataaac gcccgcgaca tcgctccaga tggtcacgcg ggaaacgccc
     2281 gccaacgcgc cgatttgcgt ggcggaatag tcggaaccgt tacggcctaa caggactgtt
     2341 tcgccgtcgt gattgcggct gataaacccg gtcacgacca gacgtttgcc aggatgctgc
     2401 gccagtagct gttgcaataa aggataagat agtccttcat caacctgcgg ctgtgcggcg
     2461 cgttcggcgc gtaaaaatgc gcgcgcgtcc agccaggcgg catccagccc ctgctgattc
     2521 aggacggcgg acatcaatct cgccgaccaa atttcgccgt gtccgacgat ctcagcatag
     2581 acggcatccg ttacgccgcc gtcgagcaag gcggcaagac gttccagatc gctgataaaa
     2641 gcgctggtta agtcatctgc cgcgtcggcg ggaagcagcc cgctaatcag atcgcactgg
     2701 tagcggcgta acgtctgtaa tacctgatgc gcagaaaggc gatcggtctg gcttaacttg
     2761 agccagctaa tcaactggtt ggtggtactg cctgcggcgg acactaccat catatcgtca
     2821 ggctgcgaat actccgccat aatgcctgcg acacgcaggt aacacttcac atccgccaga
     2881 ctactgccgc caaatttatg cagttgacga cctttcgccc ctgcctgcgc aatcacactc
     2941 atgtttaccc cttgtttgca gcccggaagc cattttccag gtcggcaatt aaatcttcgc
     3001 catcttcaat accggtggag atacgcagta gcgtttcgga gatcccggcg gcggcacgcg
     3061 cctgcggcga cataccggca tgcgtcatgg tggcggcgtg agagatcaaa ctttccactc
     3121 cccctaaaga ttccgccagc gtaaacagcg acagcccgcc cagaaaacga cgtagcgtct
     3181 cctcatcccc atccagttca aaactcaaca ttgcgccaaa gcctttttgc tgacgcgcgg
     3241 caatctcatg tccctgatta ttcggcagcg acgggtgata cagttttttc accaacggct
     3301 gggtttgcag atatttcaca atcgcctgcg cgttgcgctg cgccagctcc atacgcggca
     3361 ccagagttcg caaaccgcgc agcagcagat agctatcaaa cgccccgccg gtcacgccaa
     3421 tattattcgc ccaccacgcc agttcagtga ccatttccgg atccttagca atcatcacgc
     3481 cggccacgac atccgaatga ccattgagat atttcgtgca tgaatgcaac accagatcgg
     3541 cacccaacgc cagcggattt tgcagcgccg ggcttaaaaa tgtgttatca acgacgctca
     3601 ctgcgcccgc ctcgcgcgcc agccgacaga ttttcgcaat atccaccacg cgtaacaatg
     3661 gattacttgg actttctacc agtaccagct tcggtttttc ttccagcgcc gcctgtaagg
     3721 cgcgttcatc gccctgatcg acaaaccgca cacgataaca gccgcgcgtc gccagactgt
     3781 caaacagacg ataactgccg ccgtagcaat catgcggcgc gaccagcaga tcgcccggct
     3841 tgaggaaaac ggtggtgacc agatgaatcg ccgacatgcc ggtattcgtc aatactgcgc
     3901 ccgcgccgcc ttccagttcc gctaatgcgc gctgaaccac atcacgcgtg ggattaccgc
     3961 ggcgggaata atcatgcgcg cgcggctcat tgaaaccggt aaagttatag gtactggaga
     4021 gatggattgg cggcacaacg cagccgtatt gttcgtcatc gtttaatccg ctacgcactg
     4081 cgatagtggc ctgtttacgc gtcatatgaa gatattcctg gctgagtcgg tgaaagtcag
     4141 gccacagatt aaccactacc acaatagacg tcaatacatc tggacaccta aacttctttg
     4201 cgtatagatt gagcaaaccg caaatagccg ttaaaattat atgcattagc gcacatctgc
     4261 gaccgctaac ttcgtgtcag ggccgcgcca ctacggtaaa ctacgcgcga ttatggtccg
     4321 ggctcaggtt cagacctcaa tattaatgac gaagaggatt aagtatctca tggctgaatg
     4381 gagcggcgaa tatatcagcc catacgctga gcacggtaag aagagtgagc aagtcaaaaa
     4441 aattacggtt tccattcctc tgaaggtgtt aaaaatcctc accgatgaac gtacgcgtcg
     4501 tcaggtgaac aacctgcgcc acgccaccaa cagcgagctg ttgtgtgaag catttctgca
     4561 cgcctttacc gggcaaccct tgccggatga tgccgatctg cgaaaagagc gcagcgatga
     4621 aatcccggaa gcggcaaaag agatcatgcg tgagatgggg attgacccgg aaacgtggga
     4681 atactgatag caaagcatgc ggtcagaacg cctctggccg cgctttttta acgatttccc
     4741 ctgtacacgg ctatctccga cattgttcta aacgttcatc ttcccgaata gccctcggtg
     4801 gataaatttg tcagacatga taagtttctc ttcgttattt tcctgaaaaa attcccggca
     4861 tgccataatc gatataattt tattatattt aaaattccaa tatttattta atgtttcacg
     4921 tagcaaagcg tacatgaata ataatacacc g
//
LOCUS       DAJVBX010000247         4946 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.247, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000247 DAJVBX010000000
VERSION     DAJVBX010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4946)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4946)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4946
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.247"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(34..1038)
                     /gene="cra"
                     /locus_tag="OPV72_004105"
     CDS             complement(34..1038)
                     /gene="cra"
                     /locus_tag="OPV72_004105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite repressor/activator"
                     /protein_id="HCR9916260.1"
                     /translation="MKLDEIARLAGVSRTTASYVINGKAKQYRVSDKTVEKVMAVVRE
                     HNYHPNAVAAGLRAGRTRSIGLVIPDLENTSYTRIANYLERQARQRGYQLLIACSEDQ
                     PDNEMRCIEHLLQRQVDAIIVSTSLPPEHPFYQRWANDPFPIVALDRALDREHFTSVV
                     GADQDDAEMLAEELRKFPAETVLYLGALPELSVSFLREQGFRTAWKDDPREVNFLYAN
                     SYEREAAAQLFEKWLETHPMPQALFTTSFALLQGVMDVTLRRDGKLPSDLAIATFGDH
                     ELLDFLQCPVLAVAQRHRDVAERVLEIVLASLDEPRKPKPGLTRIRRNLYRRGILSRS
                     "
     gene            complement(1322..1813)
                     /gene="ilvN"
                     /locus_tag="OPV72_004106"
     CDS             complement(1322..1813)
                     /gene="ilvN"
                     /locus_tag="OPV72_004106"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001563086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HCR9916261.1"
                     /translation="MRRILSVLLENESGALSRVIGLFSQRGYNIESLTVAPTDDPTLS
                     RMTIQTVGDEKVLEQIEKQLHKLVDVLRVSELGQGAHVEREIMLVKIQASGYGREEVK
                     RNTEIFRGQIIDVTPTLYTVQLAGTSDKLDAFLASLRDVAKIVEVARSGVVGLSRGDK
                     VMR"
     gene            complement(1816..3540)
                     /gene="ilvI"
                     /locus_tag="OPV72_004107"
     CDS             complement(1816..3540)
                     /gene="ilvI"
                     /locus_tag="OPV72_004107"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020079613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase 3 large subunit"
                     /protein_id="HCR9916262.1"
                     /translation="MEMLSGAEMVVRSLIDQGVKQVFGYPGGAVLDIYDALHTVGGID
                     HVLVRHEQAAVHMADGLARATGDVGVVLVTSGPGATNAITGIATAYMDSIPLVILSGQ
                     VATSLIGYDAFQECDMVGISRPVVKHSFLVKQTEDIPLVLKKAFWLAASGRPGPVVVD
                     LPKDILNPAKKMPYVWPETVSMRSYNPTTSGHKGQIKRALQTLASAKKPVVYVGGGAI
                     SAACYAPLRHIIETFNLPVVSSLMGLGAFPATHRQSLGMLGMHGTYEANMTMHNADVI
                     FAVGVRFDDRTTNNLAKYCPNATVLHIDIDPTSISKTVNADIPVVGDARLVLEQMLEL
                     LAQDAPSQPQDDIRDWWQQIESWRARQCLKYDAESESIKPQAVIETLWRLTKGDAYVT
                     SDVGQHQMFAALYYPFDKPRRWINSGGLGTMGFGLPAALGVKMALPKEMVVCVTGDGS
                     IQMNIQELSTALQYELPVLVLNLNNRYLGMVKQWQDMIYSGRHSQSYMQSLPDFVRLA
                     EAYGHVGLQINRPDELESKLSEALEHVRNNRLVFVDVTVDGSEHVYPMQIRGGGMDEM
                     WLSKTERT"
     gene            complement(3862..4806)
                     /gene="leuO"
                     /locus_tag="OPV72_004108"
     CDS             complement(3862..4806)
                     /gene="leuO"
                     /locus_tag="OPV72_004108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LeuO"
                     /protein_id="HCR9916263.1"
                     /translation="MPEVKTEKPHLLDMGKPQLRMVDLNLLTVFDAVMQEQNITRAAH
                     TLGMSQPAVSNAVARLKVMFNDELFVRYGRGIQPTARAFQLFGSVRQALQLVQNELPG
                     SGFEPTSSERVFNLCVCSPLDNILTSQIYNRVEKIAPNIHVVFKASLNQNTEHQLRYQ
                     ETEFVISYEEFRRPEFTSVPLFKDEMVLVASRKHPRISGPLLEGDVYNEQHAVVSLDR
                     YASFSRPWYDTPDKQSSVAYQGMALISVLNVVSQTHLVAIAPRWLAEEFAESLELQIL
                     PLPLKLNSRTCYLSWHEAAGRDKGHQWMEDLLVSVCKR"
BASE COUNT         1225 a         1398 c         1168 g         1155 t
ORIGIN      
        1 cggcagaaga gagagtcttt taccgccggt cctttagcta cggctcagaa tgccgcgacg
       61 atacaggttt cgccgaatac gcgttaagcc gggtttcggt ttacgcggtt catcaagact
      121 tgccagcaca atctccagca cgcgttccgc gacatcacga tgacgctgcg ccaccgccag
      181 taccgggcat tgcagaaaat ccagcagctc atgatcgcca aaggtcgcaa tcgctaaatc
      241 cgaaggcagt tttccatcgc gccgcagcgt aacgtccatc acgccctgta atagcgcgaa
      301 tgatgtcgta aagagcgcct gcggcatagg atgcgtttcc agccatttct caaacagctg
      361 cgcggcggct tcgcgctcat agctgttggc atataagaaa ttcacctccc gcggatcgtc
      421 tttccatgcg gtgcggaacc cctgctcgcg caggaaactg acggacaact ccggcagcgc
      481 gcccaaataa agcaccgttt ccgccgggaa tttacgcagc tcttccgcca acatctcggc
      541 atcatcctga tcggcgccga ccacgctggt gaaatgttcg cgatccagcg cgcggtcgag
      601 cgcgacgatg gggaacggat cgttggccca gcgctgatag aagggatgct ccggcggtaa
      661 cgaagttgaa acaatgattg catccacctg gcgttgcaaa aggtgctcaa tgcagcgcat
      721 ttcgttatcc ggctgatctt cagaacaggc gatcagcagt tggtagccac gctggcgtgc
      781 ctggcgctca agatagtttg cgatacgggt gtagctcgtg ttttcaaggt ccgggatcac
      841 cagaccaatg gaacgtgtgc gtccagcacg cagcccggca gccacagcgt taggatggta
      901 attgtgctca cgcactaccg ccatgacttt ttctacggtt ttgtcgctca cgcggtattg
      961 ctttgcttta ccgtttataa cgtagcttgc agttgtgcgc gagacaccgg ccagccgagc
     1021 gatttcatcc agtttcacaa ttgccccttg tgtaaattgt acaaaccata acctttatgt
     1081 cggcatgggt taaaatcgtt aacatctaag cgcagtttga tcactccggc aaccgctttt
     1141 attccgggtt accacggatt tcgcaaaaaa aagcccaacc gatgatattg ggttgggcga
     1201 taattcctgt tggctgatat ccggcaaacc tgcctgatgg cgctacgctt atcggacctg
     1261 ggccagatat cagcctgtag accggataaa acgcaagcgc gtcgtcatcc ggcgaatctg
     1321 ctcagcgcat aaccttatcg ccgcgcgaaa gcccgacgac gcctgaacgc gccacttcaa
     1381 caattttcgc cacatcgcgc agcgaggcca gaaaagcatc cagtttatcg ctggtgcccg
     1441 ccagttgaac ggtatacaac gttggcgtaa cgtcaataat ctgaccacgg aaaatttccg
     1501 tattacgctt cacctcttcc cgtccgtagc cgctggcctg gattttcacc agcatgattt
     1561 cccgctcaac gtgcgctccc tgtcccagct cgctgacgcg cagcacatca accagcttgt
     1621 gcagttgctt ttcaatttgc tcaagcactt tttcatcgcc taccgtctgg atagtcatgc
     1681 gcgacaacgt cggatcgtct gtcggcgcaa cggtcaggct ttcaatatta tatccgcgtt
     1741 gcgaaaagag gccgataacc cgcgataacg ccccagattc gttttccagt aataccgata
     1801 aaatccggcg catcatcagg tcctctccgt tttgcttaac cacatttcgt ccatcccgcc
     1861 cccgcgaatc tgcatcggat agacatgctc gctgccatca acggtgacat cgacgaacac
     1921 cagtcggtta ttacgcacat gctcaagggc ttcgctgagt ttactttcca gctcatccgg
     1981 acggttaatc tgcagcccga catggccata tgcttccgcc aggcgcacaa aatccggtaa
     2041 cgactgcata taagactgag aatggcgacc ggaatagatc atatcctgcc actgtttcac
     2101 catccccagg taacggttgt tcaggttcag aaccagtacc ggcagttcat actgtaaggc
     2161 tgtcgacagc tcctgaatgt tcatctgtat actgccatcg ccggtcacgc agaccaccat
     2221 ttctttcggc agggccattt taacgcccag tgcagccggt aggccaaacc ccatcgtgcc
     2281 gagcccgcca gagttaatcc agcgacgtgg cttatcgaac gggtagtaga gggcggcaaa
     2341 catctggtgt tgtcctacat cggacgtcac gtacgcatca cccttcgtca gacgccagag
     2401 agtttcaatc accgcctggg gtttaatgct ttcgctttcc gcgtcatatt tcaggcactg
     2461 acgggcgcgc cagctctcta tctgctgcca ccagtcgcga atatcatcct gcggctgaga
     2521 cggcgcatcc tgcgccagta gctccagcat ttgttccagt accaggcgtg catcgcccac
     2581 caccgggata tcagcgttaa ccgttttgga tatggacgtc gggtcaatgt cgatgtgtaa
     2641 taccgtcgcg ttcggacaat atttagcgag attattcgtc gtgcggtcgt caaatcgtac
     2701 gccaacagcg aaaatcacgt cggcgttatg catggtcata ttggcttcat aagtgccatg
     2761 cattcccagc attcctaacg actggcgatg agtagcagga aacgcgccca gtcccattaa
     2821 tgaagagacc accggcaggt taaaggtttc aatgatgtgg cgcagcggcg catagcaggc
     2881 cgcgcttatc gcccctcccc caacatagac caccggcttt tttgccgacg ccagcgtttg
     2941 caaggcacgc ttaatttgtc ctttatgtcc tgatgttgtg ggattgtaag agcgcatact
     3001 gaccgtttcc ggccagacat acggcatttt tttcgccgga ttcaaaatat ctttcggcag
     3061 atccacgacc accggcccag gacgtccgct tgccgccagc cagaaggcct ttttaagcac
     3121 caggggaata tcttccgtct gtttgaccag gaagctatgt ttgaccaccg gtcgggaaat
     3181 ccccaccatg tcgcactcct gaaaggcatc atagccaatc aatgaggtgg cgacctggcc
     3241 ggaaagaatc accagcggaa tggaatccat ataggccgta gcaatccctg taatcgcatt
     3301 ggtcgctccc ggtccggaag tcaccagcac cacgccaacg tcgccagtgg ctcgcgccag
     3361 gccatccgcc atatgcaccg cggcctgctc atgacgcacc agcacatgat cgatccctcc
     3421 aacggtatgt agcgcatcat aaatatcaag cactgcgcct ccaggatagc cgaacacctg
     3481 ctttacgcct tgatcgataa gcgatcggac gaccatctcg gctccagaca acatctccac
     3541 ggcttgcctc cactttatac ctgtcatcac ggtttgacgg acaccttaac cgctcgctat
     3601 cacgcctggc aattgggtgg aatgacgtaa agatggggaa ggttagaata atcaggaggc
     3661 aagaagagaa gaaatggaga aatactccgt ctgaatcaca ccaggtaata aataatcgct
     3721 tataaatgca gacttacagc aattcatcta tttttcacag cgacgaaaag aatcgctcac
     3781 cgttaattca gcataaaatt tttgacatac gctaaaaagc agaataaacc agaatttgtt
     3841 tctgatttat tctgcccggt tttatcgctt acaaacagag actaataaat cttccatcca
     3901 ttgatgccct ttatcacgcc cagccgcttc atgccaggaa aggtagcatg tccggctatt
     3961 cagttttaaa ggcaacggca gtatttgcag ctccagcgac tccgcaaact cttccgccag
     4021 ccagcgcggg gcaatagcga ccaaatgcgt ctgcgaaacc acgttcagaa cgctgataag
     4081 cgccatgccc tgataagcca cgctcgactg tttatccggc gtgtcatacc acggccgact
     4141 aaatgacgca taacgatcga gagaaacaac cgcatgttgt tcattataaa catcgccttc
     4201 cagtagcggg ccgctaatac gcgggtgttt tcggctggcg actaaaacca tttcatcttt
     4261 aaatagcggt acgctggtaa actcaggacg acggaattct tcataactaa taacgaactc
     4321 ggtttcctga tagcgtaact gatgctcagt attctgattc aacgacgctt taaaaacgac
     4381 atgaatattt ggcgcaattt tttctacacg attataaatc tgtgacgtca ggatattatc
     4441 cagcggactg cacacgcaaa gattgaatac acgttcgctg ctggtcggct caaaccccga
     4501 tcccggcaat tcattttgca ccaattgcaa cgcctgacgg actgaaccaa ataactgaaa
     4561 tgcacgggca gtcggctgaa ttcctcgtcc atatcgaaca aaaagttcgt cattaaacat
     4621 aaccttcaga cgcgctacgg cgttactgac cgcaggctgc gacattccca gcgtgtgggc
     4681 ggcgcgcgta atattctgct cttgcattac cgcatcgaac acggtcaata ggttcaaatc
     4741 aaccatgcga agctgtggtt tgcccatatc taaaagatgc ggcttttcgg ttttgacctc
     4801 tggcatattt aactccactg tcacgcttaa ctcccttttt ctggctgaag gcagaaataa
     4861 ttcctgaaaa tatgatttac catgcatata aaataagaaa aagggaaagc gttaaaattc
     4921 ggaaaacata aagacgctga cagaga
//
LOCUS       DAJVBX010000248         4879 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.248, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000248 DAJVBX010000000
VERSION     DAJVBX010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4879)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4879)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4879
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.248"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..996)
                     /locus_tag="OPV72_004109"
     CDS             complement(<1..996)
                     /locus_tag="OPV72_004109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative fimbrial-like adhesin protein"
                     /protein_id="HCR9916264.1"
                     /translation="MKLFLFIVMLLILPETYAACTGEITYQDNLIIREDFTINPNQSA
                     TYSHNFNDTTCSGTYKITRMDPSDIIVGLYNDTVKLKLKIAWADNNTLTMPFTTGYTV
                     TVEPASSGANVNISAGSGNSVLINGVVSITSASSATQFTASLRFLGCLLAGRGWNACA
                     ADYNSYLRGAGLYSFDLFVSYDRKQTTCKPEDLTITLPNIALSELYNTGKVSNKNAAD
                     NIRLQCDNLFGNAKQTSRKMTVYLSSSDLIPDSYSVLRGAVNNGVGFILESGGKTVNI
                     SNAAEQGNASTLWKVDQVGTPLNSDMITIPIIASYYVYDRDNIKPGDLKATALIYV"
     gene            complement(1012..3501)
                     /locus_tag="OPV72_004110"
     CDS             complement(1012..3501)
                     /locus_tag="OPV72_004110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HCR9916265.1"
                     /translation="MLRMTPIASLVLLTLFTWQTQAIATETFDTHFMVGGMRDQKITN
                     FHLDENKPIPGQYELDIYVNNQWRGKYDIIVADDPGSTCISTELLKNIGVISDGLQPQ
                     GATDCIALKDVVRSGGYTFNIGVFRLDLSVPQAYVNEVEAGYVLPENWDRGINAFYTS
                     YYASQYYSDYKNSGSSESTYVRFNSGFNLLGWQAHADTTFNKTDGSSGEWKSNTLYLE
                     RGIAELLGTLRAGDQYTSSEIFDSVRFTGVRLFRDMQMLPNSKQNFTPLVQGIAQTNA
                     LVTIEQNGFVVYQKEVPPGPFSIADLQLAGGGADLDVTVREADGSINTWLVPYASVPN
                     MLQPGVSKYDFSAGRSHIEGADNQADFTQISYQYGLNNLLTLYGGTMLSNHYNAFTLG
                     TGWNTRIGAISLDATRAHSKQDNGDVFDGQSYQIAYNKYLTQTLTRFGLAAYRYSSQD
                     YRTFNDHVWANNKNNYRRDKNDVYDIADYYQNDFGRKNTFSANVSQSLPEGWGAVSLS
                     ALWRDYWGRSGTSKDYQISYSNTFQKINYTLSASQTYDEDHNEDKRFNLFISIPFDWG
                     DGITTPRRHLNVSNSTTFDDDGFTSNNIGLTGTAGSRDQFNYGVNVSHQRHDSETTAG
                     TNLTWNTPVATLNGSYSQSSNYTQTGGSISGGVVAWSGGLNLSSRLSDTFAIMQAPGL
                     EGAYVNGQKYRTTNKKGTVVYDNLTPYRENHLMLDVSQSSSETELRGNRKVAAPYRGA
                     VVLVNFDTDQRKPWFIKAQRPDGSPLIFGYDVVDHHGHNVGIVGQGSQLFIRTNDIPP
                     EVSVPVDKEQGLSCSITFGKTVDESKVYICR"
     gene            complement(3515..4198)
                     /locus_tag="OPV72_004111"
     CDS             complement(3515..4198)
                     /locus_tag="OPV72_004111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HCR9916266.1"
                     /translation="MKILSAVLLSAIILPAHAGIVIYGTRVIYPAEKKEVVVQLVNQG
                     EQASLVQSWIDDGNTSLPPEKIQVPFMLTPPVARVAAESGQQIKIKKMPNSLPDNKES
                     LFYLNVLDIPPNSQENAGKNVLKFAMQNRIKLIWRPSRIAAVTKDSFQRIGLFRSNKT
                     VIMKNDTANWITVTDVKAGNTKINDQTIMLPPLSTQNINMKYASTSQYEVTIIDDNGN
                     YISSKINVK"
     gene            complement(4254..4784)
                     /gene="yehD"
                     /locus_tag="OPV72_004112"
     CDS             complement(4254..4784)
                     /gene="yehD"
                     /locus_tag="OPV72_004112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein YehD"
                     /protein_id="HCR9916267.1"
                     /translation="MKRSLIAASVLSAVFMSAGAFAVDEYDSGVLNINGKVVGTTCQF
                     LGTNTAEIRLNEIGADKIINLTPGQIYDAVTNQTQMPLKIKCQQGVAPRITFSSTQFD
                     SHDITFNNGSAKGVGFAVYYGSTDNQIDPETGVTLDPNSSGEYDLTFLARYARLDGDV
                     ASGDVSSTLTLTVVTD"
BASE COUNT         1373 a         1164 c          959 g         1383 t
ORIGIN      
        1 cacatagatc agcgcagtcg cttttagatc gcctggcttt atattgtctc ggtcataaac
       61 ataataactg gcgataatag ggattgttat catatcactg ttgagcggcg tgcctacttg
      121 atccactttc cataacgttg aagcattacc ctgctctgct gcatttgaaa tattcaccgt
      181 ttttccaccg ctctccagta taaatccgac gccattattc acagcaccac gcaacacaga
      241 atagctatct ggtattaaat cactgctgga gagataaacc gtcattttac gcgatgtttg
      301 tttagcatta ccaaaaagat tatcacactg gagtcgaata ttatccgcgg catttttgtt
      361 gctgaccttg cctgtgttat ataattcaga aagcgcaata ttcggtagcg tgatcgtcag
      421 atcttcaggt ttgcaggttg tctgcttgcg atcgtaggac acaaacagat caaatgaata
      481 taaccctgca cctctaagat aactattata atctgcggca caggcattcc agcctcttcc
      541 tgctagcagg caccctaaaa accgcaaact ggccgtaaac tgagttgcag aagaagcgct
      601 tgttattgat accaccccgt tgattaggac actgttccca ctaccggcag aaatatttac
      661 attcgcccca gaggaagcgg gttcaaccgt taccgtatag cccgttgtaa acggcattgt
      721 gagagtatta ttatctgccc aggcgatttt taacttcagt tttactgtat cattgtataa
      781 tcccacgatg atatcggaag gatccatacg cgttatctta taagtccctg aacaagttgt
      841 atcgttaaaa ttatggctat aagttgcgga ctgattaggg ttaatcgtaa aatcctcacg
      901 aataattaaa ttatcctgat aagtaatttc tcccgtacag gctgcgtatg tttcaggtaa
      961 aatcaataac atcacgataa aaagaaagag tttcatttca ccacctcacc actaccgaca
     1021 aatataaact ttactttcat caaccgtttt tccaaaggtg attgaacatg aaagcccctg
     1081 ctctttatct actggtacac tgacttcggg cggaatatca ttcgttcgaa taaatagctg
     1141 actaccttgt ccaacaatgc ccacattatg accatgatga tctactacat cataaccaaa
     1201 aataagaggc gagccatcag gacgctgcgc tttaataaac catggtttac gctggtcggt
     1261 atcaaaattc actagcacga cggcccctcg gtacggggcg gcaactttac ggttaccgcg
     1321 taattccgtt tcactgctac tttgcgacac atcaagcata agatggtttt cgcgatatgg
     1381 cgtaaggttg tcataaacca ccgttccttt tttattggtg gtccgatatt tttggccgtt
     1441 aacgtaggct ccttcaagtc ccggagcctg cataatcgca aaggtatctg aaagccggct
     1501 ggataaattc aacccgccac tccaggctac aaccccaccg gaaatacttc cgccggtctg
     1561 agtataattg gacgactggc tgtaactacc attaagcgtt gcaacgggcg tattccaggt
     1621 taaattcgtc cccgctgtgg tctcactatc gtgtcgctga tgactaacat tcacgccgta
     1681 attaaattga tcgcgactgc ctgccgtacc ggttaaacca atattgtttg aggtaaatcc
     1741 atcatcatca aaggtcgtcg agttcgacac attcagatga cgccgcgggg tagtaatacc
     1801 gtccccccag tcaaagggaa ttgaaataaa caggttaaaa cgtttatctt cattatgatc
     1861 ctcgtcgtaa gtctgactgg cggataacgt ataattaatt ttctggaacg tattggaata
     1921 gcttatttga taatctttac tggtgccgct acgtccccag taatcacgcc ataatgcact
     1981 cagtgatact gcgccccatc cttctggcaa ggattggctc acattagctg aaaacgtatt
     2041 tttacgccca aaatcgtttt gataataatc agcaatatcg tatacatcat tcttatcgcg
     2101 acgatagtta tttttattat tggcccagac atgatcgtta aatgtgcggt aatcctgtga
     2161 tgaataccga tacgcagcca gaccaaaccg agttaatgtt tgggtcaggt atttattata
     2221 agcaatctga taactctgac catcaaatac atcgccatta tcctgtttac tgtgcgctcg
     2281 cgtagcgtca agcgaaatgg cgccaatccg ggtattccac cccgtgccga gggtaaacgc
     2341 attataatgg ttcgatagca tcgtaccgcc ataaagcgtc aacaggttat taaggccata
     2401 ctgataactg atttgtgtaa aatcggcctg attatcggcg ccttcaatat gactacggcc
     2461 ggcggaaaaa tcatacttag agacgccagg ctgcaacatg ttcggtacgg aagcgtaagg
     2521 caccagccag gtatttatcg aaccatccgc ctcacgcacg gtgacatcaa gatccgcgcc
     2581 accgcccgcg agttgcagat ccgcaatgga aaaggggcca ggaggaacct ctttctgata
     2641 aacaacgaat ccgttctgtt cgatggttac caaagcgtta gtctgtgcaa tcccctgcac
     2701 caacggcgta aaattctgtt tcgagtttgg caacatttgc atatcgcgga acaggcgaac
     2761 gccggtaaat ctcacagaat caaaaatctc tgacgaggta tactgatccc cggcgcgtaa
     2821 tgtgccgagg agctcagcga taccgcgctc cagatacaat gtgttgcttt tccactcacc
     2881 gctgctgcca tcggttttat taaatgtggt atccgcatgc gcttgccagc ccaacagatt
     2941 gaaaccgcta ttgaaccgaa cgtaagtact ttcactactg ccagaattct tatagtcact
     3001 gtaatactgg ctggcatagt aagaagtata aaatgcattg atgccgcgat cccagttttc
     3061 aggcaataca taacccgcct cgacctcatt tacataggcc tggggaacgc tcaaatccag
     3121 ccgaaaaacg ccaatattaa aagtatagcc accgcttctc acgacatctt ttaacgcaat
     3181 acaatccgtt gctccctgcg gttgcagacc atcgcttatc acaccaatat ttttcaacaa
     3241 ctcagttgaa atacacgtgc taccgggatc atcggcaaca atgatatcgt atttacctcg
     3301 ccattgattg ttgacataaa tatccaattc gtactgtccc ggaattggct tattctcatc
     3361 cagatggaaa tttgttattt tttgatctct cattcccccc accataaaat gagtatcaaa
     3421 cgtttccgtc gcgatagcct gcgtttgcca ggtaaacaga gtcaataaaa caagcgaagc
     3481 gatgggcgtc atccttagca tgatgaactc ctgtttattt tacattaatt ttgctactaa
     3541 tatagttacc attatcatca ataatcgtta cttcatactg gcttgttgac gcatatttca
     3601 tgttaatatt ttgcgtcgat agcggtggca gcatgatagt ttgatcatta atcttagtat
     3661 ttcctgcttt tacatccgtc acggtaatcc agtttgcagt atcatttttc atgatgacag
     3721 ttttattact gcgaaataaa ccaatcctct gaaaactgtc tttggttacg gcggcaattc
     3781 gactggggcg ccatattaat tttattcgat tctgcattgc gaatttaagc acatttttac
     3841 cggcgttttc ctggctgttt ggtggaatat caagcacatt cagataaaac agactttctt
     3901 tgttgtccgg taagctatta ggcattttct tgattttgat ctgctgacca gactcagcgg
     3961 caacgcgcgc cactggcggc gtcagcataa atggcacctg aattttttct ggcggtaatg
     4021 aagtgttacc gtcatcaatc caggactgta ccagcgaagc ttgctcgccc tgattcacca
     4081 attgtacaac gacttctttc ttctctgccg ggtaaatcac acgcgtacca taaataacaa
     4141 taccagcatg cgcaggcaaa attatggcag ataataatac tgcagataat attttcatat
     4201 ttacacggcc ttgcttataa aaaaccggcg acgaacgccg ccggttgaat aaattagtca
     4261 gtaacaaccg ttaaagtcag tgttgagcta acatcaccag aagcaacatc accgtctaaa
     4321 cgcgcatagc gtgctaaaaa agtcaggtcg tattcaccgc tgctatttgg atctagtgtc
     4381 acccccgtct ctggatcaat ctgattatcc gtacttccgt agtaaaccgc aaaaccgaca
     4441 cctttggcag acccgttatt aaatgtgata tcgtggctgt caaattgcgt tgaagagaag
     4501 gtaatacgcg gcgctacacc ctgttgacat tttattttca acggcatctg agtttgatta
     4561 gttactgcgt cataaatctg acccggggtt aaattaatta ttttatccgc accaatttca
     4621 ttcagtctaa tttcagcggt gttcgtaccc aaaaattgac aggtagtacc aaccaccttt
     4681 ccgttaatat tcagaacgcc tgaatcatac tcatcaacag caaaagcccc agcgctcata
     4741 aatacagcag acaatacaga agcagcaata agtgaacgtt tcataatctc ttccttaatg
     4801 aagtaatttc tatttgttaa gagttattaa cccttgcaac gaaaattctc atagacagga
     4861 agttatcgca atgtaaaca
//
LOCUS       DAJVBX010000249         4861 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.249, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000249 DAJVBX010000000
VERSION     DAJVBX010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4861)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4861)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4861
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.249"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            7..1059
                     /locus_tag="OPV72_004113"
     CDS             7..1059
                     /locus_tag="OPV72_004113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCR9916268.1"
                     /translation="MNKFLRQLSLLALLFCWPLMSQAARTFTDQLGRQVTVPDTLDRV
                     VVLQHQTLNLLVQMNATDKIVGVMANWKQQLGDGYARLAPELAQKASLGDLTHVDPEK
                     LVALRPQVVFVTNYAPQEMIDKISRLGIPVVAISLRHDVAGEQAKMNPTLADEEQAYN
                     RGLREGITLIGDIVNKPQEAKALIEAMNKGRKMVSDRLQSVPENERVRAYMANPELTT
                     YGSGKYTGLMMAHAGALNVAASSAKGFKQVTMEQVIAWDPQVIFVQNRYPKVVNEILH
                     NPQWQVIDAVKHHRVYLMPDYAKAWGYPMPEAVGIGELWMAKKLYPEKFHDIDMQKAA
                     NDWYQRFYRTDYQGVQ"
     gene            1059..1769
                     /locus_tag="OPV72_004114"
     CDS             1059..1769
                     /locus_tag="OPV72_004114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HCR9916269.1"
                     /translation="MRILAAGSLRVVWPQLMTAFQADAVCDFGPAGLLRERIEAGEAC
                     DFFASANLAHPQALLESGRALRVAPFTTNRLCLSVRAQAMREGEDWLSLLTRRDLRIG
                     TSTAGCDPSGDYTQQLFSRMGKEGEAIRKRAVALVGGRQTLPLPAGRLAAEWLINHDY
                     TDIFIGYASYAPRLRQVNSLRVVDIPEPYNPVAEYGFACLSEQGKTLADFLLSARARL
                     ILMQHGFSEAPHMTHSQN"
     gene            complement(1837..2703)
                     /gene="yghU"
                     /locus_tag="OPV72_004115"
     CDS             complement(1837..2703)
                     /gene="yghU"
                     /locus_tag="OPV72_004115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HCR9916270.1"
                     /translation="MADNTYQPAKVWTWDKSGSGAFANINRPVSGPTHDKTLPVGKHP
                     LQLYSLGTPNGQKVTIMLEELLALGVTGAEYDAWLIRIGEGDQFSSGFVDINPNSKIP
                     ALRDNSYNPPIRVFESGAILVYLADKFGHFLPQDLAKRTETLNWLFWLQGAAPFLGGG
                     FGHFYHYAPVKIEYAINRFTMEAKRLLDVLDKQLAHHPYVAGEEYTIADMAIWPWFGN
                     VVLGNVYDAAEFLDAGSYQNVQRWAKQVAERPAVKRGRIVNRTNGPLNERLHERHDAS
                     DFENHTEDKRQS"
     gene            2930..4786
                     /gene="gss"
                     /locus_tag="OPV72_004116"
     CDS             2930..4786
                     /gene="gss"
                     /locus_tag="OPV72_004116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutathionylspermidine
                     amidase/synthase"
                     /protein_id="HCR9916271.1"
                     /translation="MSKGTTSQDAPFGTLLGYAPGGVAIYSSDYNSLDPWDDDDAAFR
                     SYIDDEYMGHKWQCVEFARRFLFLNYGVVFTDVGMAWEIFSLRFLREVVNDNILPLQA
                     FPNGSPRAPEAGALLIWQKGGEFNETGHVAIITQLLDNKIRIAEQNVIHTPLPPGQQW
                     TRELEMVVENGCYTLRDTFDDTTILGWMIQTDDTQYSLSQPDIANQSLAIRGARLPEK
                     GQFDGQWLDERDPLQKAYVQANGHVINQDPYQYFTITESAEQELIKATNELHLMYLHA
                     TDKVLKDDNLLALFDIPKILWPRLRLSWQRRRHHMITGRMDFCMDERGLKVYEYNADS
                     ASCHTEAGLILEKWAEQGYTGKGHNPAEGLINELAGAWKHSKARPFVHIMQDDDIEED
                     YHAQFMQQALHQAGFASKILRGLGELRWDDAGQLIDGDGRLVNCVWKTWAWETAMEQI
                     REVSETEYAAVPIRTGHPENEVRLIDVLLRPEVLVFEPLWTVIPGNKAILPILWSLFP
                     HHRYLLDTDFTVNDELVQTGYAVKPIAGRCGSNIDLVSHQEELLDKTSGKFATQKNIY
                     QQLWCLPKVAGKYIQVCTFTVGGNYGGTCLRGDDSLVIKKESDIEPLIVIKA"
BASE COUNT         1111 a         1234 c         1404 g         1112 t
ORIGIN      
        1 aaacctatga ataaattttt gcgccagctc tctctgctgg cgttgctttt ttgctggccg
       61 ttaatgtcac aggcggcgcg tacttttacc gatcaacttg gccgccaggt cacggttccc
      121 gataccctcg acagagtggt ggtgctccag catcaaacgc tcaatctcct tgtacagatg
      181 aatgccactg acaaaatcgt tggggtcatg gcgaactgga aacagcaatt aggcgacggc
      241 tatgcgcgtc tggcgccgga actggcgcaa aaagcctcgc tgggcgatct aacgcacgtt
      301 gatcctgaaa aactggtggc gctgcgcccg caggtggtgt ttgtcacgaa ttacgctccg
      361 caggagatga tcgacaagat cagccgtctt ggcattccgg tggtggcgat ttcgctgcgc
      421 catgatgttg ctggcgagca ggctaaaatg aacccgaccc tggccgatga agagcaggct
      481 tataatcgcg ggctgcgtga aggaataacg ctgattggcg atatcgtcaa taaaccgcag
      541 gaggcgaaag cgctgattga ggcgatgaat aaaggtcgca agatggtcag cgaccgtttg
      601 cagtcggttc ctgaaaatga gcgagttcgc gcctatatgg cgaatccgga gctgaccacc
      661 tacggttccg gtaaatacac cggtctgatg atggcccatg cgggggcgct gaatgtagcg
      721 gcatcctcgg cgaaaggctt taagcaggtg acaatggagc aggtgatcgc ctgggatcca
      781 caagtaatct ttgtccagaa tcgctatcca aaggtcgtca atgagatcct gcacaatccc
      841 cagtggcagg tcattgacgc ggtgaagcat catcgggttt acctgatgcc ggattatgcc
      901 aaagcctggg gatatccgat gccggaggcg gtgggaatcg gcgaactatg gatggcgaaa
      961 aaactctatc cggaaaaatt ccacgatatt gacatgcaaa aggccgctaa cgactggtat
     1021 caacgttttt accgtactga ctatcagggc gtacagtgat gcgaatactg gctgcgggga
     1081 gcttgcgcgt cgtctggccg cagctaatga cggcgtttca ggcggatgcg gtatgtgatt
     1141 tcggtccggc ggggctgtta cgtgaacgca tcgaagcggg cgaagcatgc gacttttttg
     1201 cttcggcgaa cctggcgcat ccgcaggcgc tgctggaaag cgggcgggca ctgcgggtcg
     1261 cgccttttac gacgaaccgt ttgtgtctga gcgtgcgggc acaggcgatg cgtgaaggcg
     1321 aggactggct gtcgctatta acccggcggg atctgcggat cggcacctca acagcaggtt
     1381 gcgatccttc cggcgattat acgcagcagc ttttttcgcg gatgggcaag gagggcgaag
     1441 cgatccgaaa acgcgcggta gcgctggttg gcggcagaca gactttgccg ttaccggcgg
     1501 gccggctggc ggcggaatgg ctcatcaatc atgattacac cgatatcttt atcggctatg
     1561 ccagctatgc tcccaggcta cggcaggtta attcgctgcg agtggttgat atcccggaac
     1621 cttataatcc cgtggctgaa tatggctttg cctgcctgag cgagcaggga aaaacgcttg
     1681 ccgacttttt actgtcagca cgggcgaggt tgattctcat gcaacatggg tttagtgaag
     1741 cgccgcatat gacgcactcg cagaactgat aagcgaagcg tcagcaggga ataccatgcc
     1801 ggatgacgac attactacct catccggcat tatggtttaa ctttgacgtt tatcttcggt
     1861 atggttttcg aagtcgctgg cgtcatggcg ttcatgaagc cgttcgttca atgggccgtt
     1921 ggtccggttg acaatgcgcc cccgctttac cgccggacgt tcggctacct gtttcgccca
     1981 gcgttgtacg ttttgataac ttccggcatc cagaaactcc gctgcatcat agacattccc
     2041 cagcaccacg ttgccgaacc acggccagat ggccatatcg gcaatagtgt actcttctcc
     2101 cgcgacatac gggtggtgag ctaactgctt atccagcacg tccagcagac gcttggcttc
     2161 catggtgaag cgattaatgg cgtactcaat ttttaccggc gcataatgat agaagtgacc
     2221 gaaaccgccg ccgaggaacg gcgccgcgcc ctgtagccag aacaaccagt taagggtttc
     2281 tgtgcgctta gccagatcct gcggcaggaa atggccaaac ttatccgcca gataaacaag
     2341 aattgcgccc gactcaaaaa cccgaatcgg cgggttgtat gagttatcgc gcagcgccgg
     2401 aatttttgag ttcggattga tgtcaacaaa gccgctggag aactgatcgc cctcgccgat
     2461 gcgaatcaac caggcgtcat attcggcgcc ggtcacgccc agcgccagga gttcttccag
     2521 cataatggtc actttctggc cgttaggcgt ccccagcgaa tagagctgta acggatgttt
     2581 gccgacgggc agcgttttgt cgtgcgtcgg gccggaaacc gggcgattaa tgttagcgaa
     2641 cgcgccgctg ccggatttat cccacgtcca gacttttgcg ggttgataag tattatctgc
     2701 catattgacc tgccttcaca gtggtggtgt tgaagcagtg tagcagcttg ctaaccggac
     2761 atttaaccga ttgggacatt ccgacgagtg aaattttaac cttctggcct cagtgtgcct
     2821 tattgaggtg tatgattatg tcgacctctg tccggttagt gtcacagagc agacaatcag
     2881 agcgaaatca cgccaggctg ctcaggcggt cttgttttga ggtaagtgca tgagcaaagg
     2941 aaccaccagt caggatgccc ccttcgggac attattgggt tacgcccccg gcggcgtagc
     3001 gatctactct tcagattaca attccctcga tccgtgggac gacgacgacg cagcttttcg
     3061 tagctacatc gacgatgaat acatggggca taaatggcag tgcgtggaat ttgcccgccg
     3121 ttttctcttt ctgaattatg gcgttgtttt tactgacgtc ggcatggcct gggaaatttt
     3181 ctcgctgcgt tttctgcgcg aggtcgtgaa tgacaatatt ttgcctttgc aggccttccc
     3241 gaacggttcg ccgcgcgcgc cggaggccgg ggcgttgctc atctggcaaa agggcggcga
     3301 gtttaacgaa accgggcacg tcgcgattat cacccaactc ctggataaca aaattcgcat
     3361 tgctgagcaa aacgttatcc acacgccatt gccgccaggg cagcagtgga ctcgcgaact
     3421 ggaaatggtc gtagaaaacg ggtgttacac cctgcgcgac acctttgatg acacgacgat
     3481 tttaggctgg atgatccaga ccgacgacac gcaatacagt ttgtcacagc ctgacatcgc
     3541 gaatcagtcg ctggcgattc gcggcgcaag gctgccagag aaaggtcagt ttgacggtca
     3601 gtggctggat gagcgcgatc cgttacaaaa agcctatgta caggcgaacg gacacgttat
     3661 caatcaggac ccgtaccagt attttaccat caccgagagc gccgaacagg agcttatcaa
     3721 agcgaccaat gagttgcatt tgatgtacct gcacgccacg gacaaagttt taaaagacga
     3781 taatctgctg gcgctattcg atatccccaa aattctttgg ccgcgcctgc gtctctcctg
     3841 gcagcgccgt cgtcaccata tgatcaccgg tcgtatggat ttctgcatgg atgaacgcgg
     3901 gctgaaagtc tatgaataca atgccgattc cgcatcatgc cataccgaag cgggattaat
     3961 tctcgaaaaa tgggctgagc agggctatac cggtaaaggg cataacccgg cggagggctt
     4021 aattaacgag ctggcaggcg cctggaaaca cagtaaagcg cgtcctttcg tccatatcat
     4081 gcaggatgat gatatcgagg aggactatca cgcgcagttt atgcagcagg cgctgcatca
     4141 ggccggtttc gcgagcaaaa ttctccgcgg gctgggcgag ttgcgctggg atgacgccgg
     4201 gcagttgatc gatggcgacg gacggctggt gaattgtgtc tggaaaacct gggcgtggga
     4261 aacggcaatg gagcagatac gcgaagtcag cgagacggag tatgccgcag tgcctattcg
     4321 taccgggcac ccggaaaatg aagtccggct gattgatgta ttactgcgcc cggaagtgtt
     4381 ggtgtttgaa ccgctgtgga cggtgatccc gggtaacaaa gcgatcctgc ccatcctgtg
     4441 gtcgctcttc ccacatcatc gctatttgct cgacacggat tttaccgtta acgatgagct
     4501 ggtgcagacc ggctatgcgg taaaaccgat tgccggacgt tgcggtagta atattgattt
     4561 ggtgagccat caggaagaac tcctggataa aaccagcggc aagttcgcca cgcagaaaaa
     4621 tatctatcag cagttgtggt gcctgccgaa ggtcgccggg aagtatattc aggtctgtac
     4681 gtttaccgtg ggcggtaact acggcggtac gtgcctgcgc ggcgatgatt cattagtcat
     4741 taaaaaagag agcgatattg aaccgttaat cgtcatcaaa gcgtaacggg gtcattctcg
     4801 tcgggatatc ggcgttggcg ccgatatccc gcctgttgtg tttaccaacg aacggctgtc
     4861 a
//
LOCUS       DAJVBX010000250         4804 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.250, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000250 DAJVBX010000000
VERSION     DAJVBX010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4804
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.250"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(32..790)
                     /gene="chbG"
                     /locus_tag="OPV72_004117"
     CDS             complement(32..790)
                     /gene="chbG"
                     /locus_tag="OPV72_004117"
                     /EC_number="3.5.1.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin disaccharide deacetylase"
                     /protein_id="HCR9916272.1"
                     /translation="MERVLIVNADDFGLSKGQNYGIVEAYRNGVVTSTTALVNGEAID
                     HAAQLSRELPALGVGMHFVLTLGKPVSEMPGLTRDGLLGKWIWQMAEEDTLPLDEIAH
                     ELACQYQRFIDVFGREPTHLDSHHHVHMFPQIFPIVARFAAQRGIALRIDRQTVLNAD
                     DLPSDLRSTQGFSSEFYGEEITEACFLRILDASAHRGEASLEVMCHPAFVDNIIRQSA
                     YCYPRLTELEVLTSASLKAGIAERVYRPGSFLDI"
     gene            complement(803..2158)
                     /locus_tag="OPV72_004118"
     CDS             complement(803..2158)
                     /locus_tag="OPV72_004118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HCR9916273.1"
                     /translation="MSQKLKVVTIGGGSSYTPELLEGFIKRYHELPVTELWLVDVEDG
                     KKKLGIIYDLCQRMIDKAGVPLKLYKTLDRREALKGANFVTTQLRVGQLKARELDERI
                     PLSHGYLGQETNGAGGLFKGLRTIPVIFDIIKDVEELCPNAWVINFTNPAGMVTEAVY
                     RHTNFKKFIGVCNIPVDMKMFIHDVLALNENDDLSIDLFGLNHMVFIKDVLVNGTSRF
                     AELLDGVASGQLKASTVKNIFDLPFSEGLIRSLNMLPCSYLLYYFKQKEMLAIEMGEY
                     YKGGARAQVVQKVEKQLFDLYKNPELNVKPKELEQRGGAYYSDAACEVINAIYNDKQT
                     EHYVNIPHHGHVENIPADWAVEMTCILGRNGATPHPRITRFDEKVLGLIHTIKGFEVA
                     ASNAALSGNFNDVLLALNLSPLVHSDRDAEVLARELILAHEKWLPNFAACIEALKGKH
                     H"
     gene            complement(2283..3125)
                     /gene="chbR"
                     /locus_tag="OPV72_004119"
     CDS             complement(2283..3125)
                     /gene="chbR"
                     /locus_tag="OPV72_004119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator ChbR"
                     /protein_id="HCR9916274.1"
                     /translation="MMQLQVNATEIKTVYEQQLFNGKNFHVFIYNKTESVTGLHQHDY
                     YEFTLVLTGRYYQEINGKRVLLERGDFVFIPVGSNHQSFYEFGATRILNVGISKRFFE
                     QHYLPLLPFCFVASQVYRANSTFLTYIETVIASLNFRGNGLDEFIEVVTFYIINRLRH
                     YREEQVYDDIPQWLKATVEIMHDKTQFGEHALENMVRLSAKSQEYLTRATRRYYSKTP
                     MQIINEIRINFAKKQLEMTNYSVTDIAYEAGYSSPSLFIKTFKKMTSFTPNSYRKRLT
                     EINE"
     gene            complement(3136..3483)
                     /gene="chbA"
                     /locus_tag="OPV72_004120"
     CDS             complement(3136..3483)
                     /gene="chbA"
                     /locus_tag="OPV72_004120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N,N'-diacetylchitobiose transporter subunit
                     IIA"
                     /protein_id="HCR9916275.1"
                     /translation="MFDLENVVDNQTAAEELEEVVMGLIINSGQARSLAYGALRKAKE
                     GDFEAAKAMMDQSRIALNEAHLVQTKLIEGDQGEGKMKVSLVLVHAQDHLMASMLARE
                     LIAELIELHEKLK"
     gene            complement(3534..>4804)
                     /gene="chbC"
                     /locus_tag="OPV72_004121"
     CDS             complement(3534..>4804)
                     /gene="chbC"
                     /locus_tag="OPV72_004121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PTS N,N'-diacetylchitobiose transporter subunit
                     IIC"
                     /protein_id="HCR9916276.1"
                     /translation="GFIRLMPLTLAGAMFVLINNVFLSFGEGAFFYSMGIRLDASTIE
                     TLNGLKGIGGNVYNGTLGIMSLMAPFFIGMALAEERKVDALAAGLLSVAAFMTVTPYS
                     VGEAYAVGANWLGGANIISGIIIGLVVAEMFTFIVRRNWVIKLPDSVPASVSRSFSAL
                     IPGFIILSIMGIIAWALSNYGSNFHQIIMDTISTPLASLGSVVGWAYVIFVPLLWFFG
                     IHGSLALTALDSGIMTPWALENISIYQQYGSVDAALEAGKTFHIWAKPMLDSYIFLGG
                     SGATLGLIIAIFLASRRADYRQVAKLALPSGIFQINEPILFGLPIIMNPVMFIPFILV
                     QPILAAITLVAYYLGIIPPITNIAPWTMPTGLGAFFNTNGSVAALLVALFNLAVATLI
                     YLPFVVVANKAQNAIEQEESEEDIANALKF"
BASE COUNT         1264 a         1306 c         1076 g         1158 t
ORIGIN      
        1 gcggcgcatt cttgcgccgc aaactcagga gctaaatatc aagaaaactg ccaggacgat
       61 atacacgttc cgcaatccct gccttgagtg acgcagacgt caacacctcc agttcagtta
      121 agcgggggta acaataggcg ctctggcgaa taatgttgtc cacaaacgcc ggatgacaca
      181 tcacctccag agaggcttct cctcgatgcg ccgaggcatc cagaatgcgt aaaaagcacg
      241 cttcggtgat ctcctcgccg taaaattcac tactaaatcc ttgagtgctg cgcaaatccg
      301 acggcagatc gtctgcattc aacaccgtct ggcggtcaat acgtaacgca atcccgcgct
      361 gcgccgcaaa gcgggcgacg atggggaaaa tttgcgggaa catatgcaca tgatgatgac
      421 tgtcgagatg cgttggctcg cggccaaata cgtcgatgaa acgctgatac tgacacgcca
      481 gttcatgcgc aatttcatcc agcggaagcg tatcctcctc cgccatttgc cagatccatt
      541 tccccaacag gccgtctcgc gtcaggcccg gcatctctga caccggtttg cctaacgtca
      601 aaacaaaatg cattcccacc ccaagcgcag gcagctcgcg gctaagctgc gccgcatggt
      661 caatagcctc gccattgacc agcgccgtcg tggaggtcac aacgccgttg cgatatgctt
      721 caacaatgcc gtaattttgc cctttactca ggccaaaatc atcggcattc acaatcaaca
      781 cgcgttccat agcctacctc tgtcagtggt gcttaccttt aagcgcttcg atgcaagcgg
      841 caaaattagg cagccatttt tcatgcgcca gaatgagctc acgcgccagg acttctgcgt
      901 ctcggtcgga atgcaccagc ggactcaggt taagcgccag cagcacatca ttaaagtttc
      961 cgctcagcgc cgcattgctg gccgcgacct caaatccttt aatagtgtgg ataagcccca
     1021 gcactttttc gtcaaaacgg gtgatacgcg ggtgcggcgt cgcgccattg cgtcccagaa
     1081 tgcaggtcat ttccaccgcc cagtccgccg ggatattctc gacatgccca tgatgtggaa
     1141 tattaacata atgctcagtc tgcttgtcat tataaatagc gttaatgact tcacaagcgg
     1201 catcggaata ataagcgccg ccgcgttgct caagctcttt cggcttcacg tttagctcag
     1261 gatttttgta caagtcgaag agttgtttct ccactttttg tacgacctga gcgcgcgcgc
     1321 cgcctttgta atattcgccc atttcaatcg ccagcatctc tttttgcttg aagtaataca
     1381 acaaataaga gcacggcagc atgttcagcg agcgaatcaa tccttcacta aacggcagat
     1441 caaagatatt ttttacggtt gacgctttca actgaccgga cgccacgcca tccagtaatt
     1501 ctgcgaaccg tgaggtgcca ttcaccagca catctttaat aaagaccata tggtttagac
     1561 caaacaggtc aatggaaaga tcgtcattct cattcagcgc cagcacgtca tgaataaaca
     1621 ttttcatgtc gacaggaata ttacatacgc cgatgaattt tttaaagttg gtatgacgat
     1681 aaaccgcttc cgtcaccatc cccgccgggt tagtaaagtt aatgacccac gcattcggac
     1741 ataattcttc aacatcctta atgatgtcaa aaataaccgg aatggtacgc aaccctttaa
     1801 ataaaccgcc agcgccgttg gtttcttgcc ccagatagcc gtggctaagc gggatacgct
     1861 cgtccagctc acgggctttg agttgaccaa cgcgtagctg ggtagtgaca aaattagcgc
     1921 ctttcagcgc ttcccggcga tccagcgttt tatacaattt tagcggaacg cctgctttat
     1981 caatcattcg ctggcagaga tcataaataa tgcccagctt ctttttcccg tcttcaacgt
     2041 caaccagcca taattcggtg acaggtaatt catggtagcg cttaataaag ccttcaagta
     2101 attcaggggt gtagctgctc ccgccaccaa tagtgacgac ttttaatttc tggctcataa
     2161 tatctccctt cagtgtatga cactgatatg tattacgcta tgcccgctcg taagaaatag
     2221 cgtgacgttc cccgcgctat tggggcaagc gtgaaatgta actaatcgag caatgtaaac
     2281 cgttactcat taatttccgt caatcgcttc cgataactat tcggcgtgaa tgaggtcatc
     2341 ttcttaaacg ttttaataaa cagacttgga ctactgtacc cggcttcata agcaatatcc
     2401 gtaaccgaat agttggtcat ttccaactgt ttcttggcaa aattaatgcg aatctcatta
     2461 atgatttgca tcggcgtttt gctgtaataa cgtcgggtgg cgcgcgtcag atactcctgg
     2521 gattttgccg acaggcgcac catattttcc agcgcatgtt cgccaaactg cgttttatca
     2581 tgcattatct ccacggttgc tttcagccat tgtggaatat catcataaac ctgctcttcg
     2641 cggtaatgac gtaagcggtt tataatataa aatgtcacca cttcgataaa ttcgtcgagc
     2701 ccattgccgc gaaaattcaa cgacgcaatc accgtttcaa tataggtaag gaaggtgcta
     2761 ttcgccctgt atacctgcga tgccacaaaa caaaacggca gtaacggaag ataatgctgt
     2821 tcaaaaaaac gtttactaat tcctacgttc agaatacgcg ttgcgccaaa ctcatagaaa
     2881 ctttggtgat tcgaccccac cgggataaaa acaaaatctc cacgttccag cagcacacgc
     2941 ttcccgttaa tctcctggta ataacgtccg gttaatacca gggtaaattc ataatagtcg
     3001 tgctgatgca gcccggtgac gctttccgtc ttgttataga taaacacatg gaaatttttg
     3061 ccattgaaga gctgctgctc ataaaccgtt ttgatttccg ttgcgttaac ctgtagctgc
     3121 atcatccgcc ccctgttatt tcagtttctc atggagctca atcaactcag cgatcagttc
     3181 acgagccagc attgaggcca tcaaatgatc ctgagcgtga accaggacca gactgacttt
     3241 cattttgcct tcgccctgat cgccttcgat gagttttgtc tgcacaagat gcgcttcatt
     3301 gagcgctatg cgcgactggt ccatcatcgc tttcgccgcc tcaaagtcgc cttctttcgc
     3361 ttttctgagc gcgccatatg ccaggctgcg cgcctgacca gaattgatga taagccccat
     3421 aacgacttct tcgagttcct cagccgctgt ctggttatct acaacatttt caagatcaaa
     3481 catagtcttt cctctgattc agcccggcat ggcatcccat gccgacgcgg agtttagaat
     3541 ttcagtgcgt tagcgatatc ttcttcgctt tcttcctgct cgatggcgtt ctgcgctttg
     3601 ttagccacca ccacgaaggg gagataaatc agggtagcga ccgccaggtt aaatagcgca
     3661 accagcaacg cggcgacact gccgttggtg ttaaagaacg cccccagccc ggttggcatg
     3721 gtccacggcg caatattggt aatcggcgga ataataccca aatagtaagc caccagcgta
     3781 atcgccgcca gaatcggctg aaccagaatg aaggggataa acatcaccgg gttcataata
     3841 atcggcaggc caaacaggat gggttcgtta atctggaaga tacctgacgg cagcgccagt
     3901 tttgccacct ggcgatagtc cgcgcgacgg gatgccagga agatagcgat gatcagaccc
     3961 agcgttgcgc cgctaccacc gaggaagata taagaatcca gcatcggttt cgcccagata
     4021 tggaacgttt taccggcttc cagcgccgca tcgacggagc catactgctg gtaaatagag
     4081 atgttttcca gcgcccaggg cgtcatgatg ccgctgtcca gcgcggtcag cgccagcgaa
     4141 ccatgaatac caaagaacca cagcagcggt acaaaaatga catatgccca ccctaccacg
     4201 ctacccagcg atgccagcgg cgtagagata gtgtccataa taatctgatg gaagttagaa
     4261 ccgtaattag acagcgccca ggcaataatc cccataatag agagaataat aaagccggga
     4321 attaatgctg agaatgaacg agacaccgaa gccggtacgc tgtccggtag tttaatcacc
     4381 cagttgcgcc ggacaataaa tgtaaacatc tccgcgacca ccaggccaat aataataccg
     4441 gagataatat tcgcgccgcc cagccagtta gcgcctacgg cataggcctc gccgacacta
     4501 tacggcgtta cggtcataaa tgccgccacg gagagcagtc cggcggccag cgcatcaacc
     4561 ttgcgctctt ccgccagcgc catgccgata aaaaatggcg ccatgagcga cataatgccc
     4621 aatgtgccgt tatagacgtt cccgccgatg cctttcaatc cattaagtgt ttcaatggtt
     4681 gaggcatcaa gccgaatgcc catggaataa aaaaacgccc cctccccaaa gctcaggaaa
     4741 acgttattaa ttaatacaaa catcgccccc gcaagggtta atggcattaa acgaataaag
     4801 ccgt
//
LOCUS       DAJVBX010000251         4635 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.251, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000251 DAJVBX010000000
VERSION     DAJVBX010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4635
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.251"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            406..1434
                     /gene="murB"
                     /locus_tag="OPV72_004122"
     CDS             406..1434
                     /gene="murB"
                     /locus_tag="OPV72_004122"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HCR9916277.1"
                     /translation="MTHSLKPWNTFGIDHCAKHIVCAENEQQLLSAWQQATREGLPVM
                     ILGEGSNVLFLENYAGTVILNRLKGIEVNETADAWHLHVGAGENWHQLVRYALDNNMP
                     GLENLALIPGCVGSSPIQNIGAYGVELHRVCDYVDCVELETGKRLRLSAAECRFGYRD
                     SIFKNEYQDRVAIVAVGLRLSKQWQPVLTYGDLTRLDPKTVTAQQVFDAVCHMRTTKL
                     PDPKVNGNAGSFFKNPVVAADIAMELLERFPNAPHYPQADGSVKLAAGWLIDQCQLKG
                     VTIGGAAVHRQQALVLINANDATSKDVVALAHHVRQKVGEKFNVWLEPEVRFIGQFGE
                     VNAVESIA"
     gene            1431..2393
                     /gene="birA"
                     /locus_tag="OPV72_004123"
     CDS             1431..2393
                     /gene="birA"
                     /locus_tag="OPV72_004123"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     ligase/biotin operon repressor BirA"
                     /protein_id="HCR9916278.1"
                     /translation="MKDTTVPLTLISLLADGEFHSGEQLGERLGMSRAAINKHIQTLR
                     DWGVDVFTVPGKGYSLPEPIQLLDADRIHSQLDSGNVAVLPVIDSTNQYLLDRIGELR
                     SGDACVAEYQQAGRGRRGRKWFSPFGANLYLSMYWRLEQGPAAAIGLSLVIGIVMAEV
                     LRELGADKVRVKWPNDLYLLDRKLAGILVELTGKTGDAAQIVIGAGINMAMRRVEEDV
                     INQGWITLQEAGITLDRNMLAAKLIYKLRAALELFEQEGLSPYLSRWKKLDNFIDRPV
                     KLIIGDKEIFGISRGIDTQGALLLEQDGVIKPWMGGEISLRSAE"
     gene            complement(2428..3378)
                     /gene="coaA"
                     /locus_tag="OPV72_004124"
                     /gene_synonym="panK"
     CDS             complement(2428..3378)
                     /gene="coaA"
                     /locus_tag="OPV72_004124"
                     /gene_synonym="panK"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HCR9916279.1"
                     /translation="MSIKEQSLMTPYLQFDRSQWAALRDSVPMTLTEDEIAQLKGINE
                     DLSLEEVAEIYLPLSRLLNFYISSNLRRQAVLEQFLGTNGQRIPYIISIAGSVAVGKS
                     TTARVLQALLSRWPEHRRVELITTDGFLHPNQVLKERGLMKKKGFPESYDMHRLVKFV
                     SDLKSGVPNVTAPVYSHLIYDVIPEGDKTVAQPDILILEGLNVLQSGMDYPHDPHHVF
                     VSDFVDFSIYVDAPEELLQTWYINRFLKFREGAFTDPDSYFHNYAKLSKEEAVNTAAS
                     LWKEINWLNLKQNILPTRERASLIMTKSANHAVEQVRLRK"
     gene            complement(3587..3760)
                     /locus_tag="OPV72_004125"
     CDS             complement(3587..3760)
                     /locus_tag="OPV72_004125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916280.1"
                     /translation="METCVLMQLKNCIKCSIAHILRYKRQKCSNFKQESINFRHFTNR
                     LTRIRRGISTLRR"
     gene            3780..3855
                     /locus_tag="OPV72_004126"
     tRNA            3780..3855
                     /locus_tag="OPV72_004126"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3813..3815,aa:Thr,seq:tgt)
     gene            3864..3948
                     /locus_tag="OPV72_004127"
     tRNA            3864..3948
                     /locus_tag="OPV72_004127"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3898..3900,aa:Tyr,seq:gta)
     gene            4065..4139
                     /locus_tag="OPV72_004128"
     tRNA            4065..4139
                     /locus_tag="OPV72_004128"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4098..4100,aa:Gly,seq:tcc)
     gene            4146..4221
                     /locus_tag="OPV72_004129"
     tRNA            4146..4221
                     /locus_tag="OPV72_004129"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4179..4181,aa:Thr,seq:ggt)
     gene            4337..>4635
                     /gene="tuf"
                     /locus_tag="OPV72_004130"
     CDS             4337..>4635
                     /gene="tuf"
                     /locus_tag="OPV72_004130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312217.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HCR9916281.1"
                     /translation="MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAA
                     RAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQM"
BASE COUNT         1176 a         1106 c         1214 g         1139 t
ORIGIN      
        1 aaggctcagt cgaaagactg ggccttttgt tttatctgtg gtctgccggt gagcactctc
       61 ctgaggagga caaatccgcc gggagcggat ttgaacgttg cgcagtaacg gcccgtaggg
      121 tggcgggcag cacgcccgcc ataaactgcc aggcatcaga caagtgaaga agcccatcct
      181 gacggacggg cttttttgcg tgtgtggtaa ctgataaaaa tgtaggcctg ataagcgcag
      241 cgccatcagg caacctgcac cgccggatgg cggctccgcc ttatccggcc tacggcaagt
      301 tcggcacaat gcctgtgtac accgccttat tccgtcgaca taaccgcaag ccttcccaac
      361 ccagatacgg taaactattg ccgattgagt atcaggaaag cagccatgac ccattcccta
      421 aaaccctgga ataccttcgg cattgatcat tgtgcaaagc acatcgtatg cgctgaaaac
      481 gaacaacaac tactgagcgc ctggcagcaa gcaactcgtg agggactgcc ggttatgatc
      541 ctgggtgaag gaagcaacgt cctgtttctg gaaaattacg ccggcaccgt gatccttaac
      601 cgcctgaaag gcattgaggt gaatgaaacc gcggacgcct ggcacctaca cgtcggcgca
      661 ggcgaaaact ggcatcagct ggttcgctat gcgctggaca acaacatgcc cggcctggag
      721 aatctggcgc tcatccctgg ctgcgttggt tcctcgccta tacagaatat tggcgcgtat
      781 ggcgtagaac tacatcgcgt ctgcgactac gttgactgcg ttgaactgga aacgggaaaa
      841 cgtctgcgtt tgtccgcggc ggaatgccgt ttcggctatc gtgacagtat cttcaaaaat
      901 gaatatcagg atcgcgttgc gatcgtcgcg gtgggtctgc gtttgtcaaa gcaatggcag
      961 ccggtgttga cctatggcga tcttactcgt ctggacccga aaacggtcac cgcgcaacag
     1021 gtgtttgatg ctgtatgcca tatgcgcacc acaaaattgc cggatcctaa agtgaatggc
     1081 aatgcgggca gcttttttaa aaatcccgtt gtcgcagccg atatcgctat ggaactgtta
     1141 gaacgatttc ccaacgcgcc gcattaccct caggcagacg gctcagtgaa gctggcggca
     1201 ggctggctga tagatcaatg tcagttgaaa ggcgtcacca ttggcggcgc tgcggtgcat
     1261 cgccaacagg cgctggtatt gattaatgcg aatgatgcga caagtaaaga tgtggtggcg
     1321 ctggcgcatc atgtccggca aaaagtgggt gaaaaattta atgtctggct ggagcctgag
     1381 gttcgcttta ttggtcagtt cggagaggtg aacgctgtgg agagcattgc atgaaagata
     1441 ctaccgttcc cctgacgctg atctcactac ttgccgacgg agagtttcac tcaggcgagc
     1501 agttgggtga acggctggga atgagccgtg cggctattaa taaacatatc cagacattac
     1561 gcgactgggg agtagatgta tttaccgttc ccgggaaagg atatagctta ccggaaccca
     1621 tccagttact ggatgctgac cgtatacata gccaactgga tagcggaaac gtggcggtat
     1681 tgcccgttat cgattcaacc aatcagtatt tacttgatcg aattggcgag ctgcgttcag
     1741 gcgatgcctg tgtagcagaa taccaacagg cggggcgtgg tcgtcgcggg cgtaaatggt
     1801 tctcaccgtt tggtgcgaat ctatatcttt caatgtactg gcgtctggag caggggcctg
     1861 cggcggcaat aggcttgagt ctggtcattg gaattgtgat ggcggaagtg ctgcgtgaac
     1921 tgggcgcaga taaagttcgt gtgaagtggc ctaacgacct ttacctactg gatcgcaaac
     1981 tggcgggtat tctggtcgag ttaaccggta aaacgggcga tgccgcacaa atagtgattg
     2041 gcgctggtat taacatggca atgcgtcgtg tagaagagga cgtgataaat cagggatgga
     2101 tcacactaca agaggccgga attacgctcg accgcaatat gctggccgca aagctgattt
     2161 ataagctacg tgctgcgctt gagctttttg agcaagaagg tctttctcct tatctttcgc
     2221 gctggaaaaa actggataat tttattgatc gtccggtaaa actaattatt ggcgacaaag
     2281 aaatatttgg tatttcccgc ggcattgata ctcagggcgc attattgctt gaacaggatg
     2341 gcgtgattaa accctggatg ggcggagaaa tatcgctgcg aagcgccgaa tagtaaaaaa
     2401 ggggagtcgg tactcccctt ttttctgtta tttccgcaat cttacctgtt ccaccgcatg
     2461 gttagcgctc ttggtcataa taaggctggc acgttctcgc gtaggtaaga tattttgttt
     2521 taaattcaac cagttaattt ctttccaaag cgaagctgct gtattaacag cttcttcttt
     2581 agataatttc gcataattgt ggaaataaga gtcaggatcg gtaaacgccc cttcgcggaa
     2641 tttcaggaag cgattgatat accacgtctg aagaagttct tctggcgcat caacgtaaat
     2701 agagaaatca acgaaatcag agacaaatac atggtgcgga tcgtgaggat aatccatacc
     2761 gctttgtaaa acattcaaac cttcaagaat caatatatca ggctgagcga cggttttatc
     2821 cccttcagga ataacatcgt aaatcaaatg agaatagact ggcgccgtca cgttcggtac
     2881 gcccgacttg aggtcagaaa cgaatttcac cagtcggtgc atatcatacg attcggggaa
     2941 cccctttttc ttcattaacc cgcgttcttt caacacctgg tttgggtgga ggaagccgtc
     3001 tgtggtaatc aattcaacac ggcggtgttc cggccagcga ctcagcaacg cttgcagaac
     3061 gcgtgctgtc gtgcttttac ccactgcgac gctgcccgcg atactgatga tgtaagggat
     3121 tcgctggccg ttagtgccca gaaactgttc caggacagcc tgacgacgca gatttgaact
     3181 gatatagaaa tttagcaaac gggagagagg taaatatatt tctgcaactt cttccagcga
     3241 taaatcttca ttaatgcctt ttaactgcgc gatctcatcc tcggtcaggg tcatcggcac
     3301 agaatcgcga agcgcagccc actggctgcg atcaaactgt aggtaaggcg tcattaacga
     3361 ttgctctttt atactcataa gcatgtttct ggctgctatt gctacatcag ttcagcgatg
     3421 aacgagggcc atccctgaca tgcaacggca cgtcacattt aagttaattt ggacaatggg
     3481 caggagggta acaccagatg gggaggaata ataagaaaaa atctcgctgt gaaagctatc
     3541 cctgagaagc aatgtgacga atataccaga tacagaagat tgctttctat cgacggagcg
     3601 ttgaaatgcc gcgtcgtatc ctggtcagac ggttggtaaa atgccgaaaa tttatgctct
     3661 cttgtttgaa attagagcat ttttgtctct tatagcgcaa aatgtgagcg atagaacatt
     3721 ttatgcaatt ttttagttgc atgagcacgc aggtctccat agaatgcgcg ctacttgatg
     3781 ccgacttagc tcagtaggta gagcaactga cttgtaatca gtaggtcacc agttcgattc
     3841 cggtagtcgg caccatcaag tccggtgggg ttcccgagcg gccaaaggga gcagactgta
     3901 aatctgccgt cacagacttc gaaggttcga atccttcccc caccaccatt ttcggccgcg
     3961 cgatggcgca gcccgagacg ataagttcgc ttaccggctc gaataaagag agtttctctc
     4021 gatattcagt gcagaatgaa aatcaggtag ccgagttcca ggatgcgggc atcgtataat
     4081 ggctattacc tcagccttcc aagctgatga tgcgggttcg attcccgctg cccgctccaa
     4141 gatgtgctga tatagctcag ttggtagagc gcacccttgg taagggtgag gtcggcagtt
     4201 cgaatctgcc tatcagcacc acttcttttc tccttcctgt ttttctcttc tgtttattag
     4261 cattcaacaa gtcgggcgtg ttgcctggtt gatgtggtga tatcaccgat ttatccgtgt
     4321 cttagaggga caatcgatgt ctaaagaaaa gtttgaacgt acaaaaccgc acgttaacgt
     4381 cggtactatc ggccacgttg accatggtaa aacaacgctg accgctgcca ttactaccgt
     4441 actggctaaa acctacggcg gtgccgcccg cgcattcgac cagatcgata acgcgccgga
     4501 agaaaaagcg cgtggtatca ccatcaacac ttctcacgtt gaatacgata ccccgacccg
     4561 ccactacgca cacgtagact gcccggggca cgccgactat gttaaaaaca tgatcaccgg
     4621 tgctgctcag atgga
//
LOCUS       DAJVBX010000252         4627 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.252, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000252 DAJVBX010000000
VERSION     DAJVBX010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4627
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.252"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            136..717
                     /locus_tag="OPV72_004131"
     CDS             136..717
                     /locus_tag="OPV72_004131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015406296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HCR9916282.1"
                     /translation="MRNKIILAMAAAGMMYGASVYAVDPPTAGPFGSGKITFTGTITN
                     SPCDIAPGDDAITVPFGQISYRKLNTADATTDSKPFTIHLQNCAFDPNIPDTAGSAGK
                     MSKVTVSFSGGANVAKKAYTTSGSAQHVGVQLLKSDNTAIIEPNTQMPEDDAQQLQAG
                     NNELNFYARLIALDNGVTPGDFTASVTYTLKYL"
     gene            837..3326
                     /gene="stdB"
                     /locus_tag="OPV72_004132"
     CDS             837..3326
                     /gene="stdB"
                     /locus_tag="OPV72_004132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial outer membrane usher protein StdB"
                     /protein_id="HCR9916283.1"
                     /translation="MKITRLAILITLTFSVLKSQATEFNASLLDSGNLSNVDLTAFSR
                     EGYVAPGNYILDIWLNDQPVREQYPVRVVPVAGRDAVVICVTTDMVAMLGLKDKIIHG
                     LKPVTGIPDGQCLELRSADSQVRYSAENQRLTFIIPQAWMRYQDPDWVPPSRWSDGVT
                     AGLLDYSLMVNRYMPQQGETSTSYSLYGTAGFNLGAWRLRSDYQYSRFDSGQGASQSD
                     FYLPQTYLFRALPALRSKLTLGQTYLSSAIFDSFRFAGLTLASDERMLPPSLQGYAPK
                     ISGIANSNAQVTVSQNGRILYQTRVSPGPFELPDLSQNISGNLDVSVRESDGSVRTWQ
                     VNTASVPFMARQGQVRYKVAAGRPLYGGTHNNSTASPDFLLGEATWGAFNNTSLYGGL
                     IASTGDYQSAALGIGQNMGLLGALSADVTRSDARLPHGQKQSGYSYRINYAKTFDKTG
                     STLAFVGYRFSDRHFLSMPEYLQRRATDGGDAWHEKQSYTVTYSQSVPVLNMSAALSV
                     SRLNYWNAQSNNNYMLSFNKVFSLGELQGLSASVSFARNQYTGGGSQNQVYATISIPW
                     GDSRQVSYSVQKDNQGGLQQTVNYSDFHNPDTTWNISAGHNRYDTGSNSSFSGSVQSR
                     LPWGQAAADATLQPGQYRSLGLSWYGSVTATAHGAAFSQSMAGNEPRMMIDTGDVAGV
                     PVNGNSGVTNRFGVGVVSAGSSYRRSDISVDVAALPEDVDVSSSVISQVLTEGAVGYR
                     KIDASQGEQVLGHIRLADGASPPFGALVVSGKTGRTAGMVGDDGLAYLTGLSGEDRRT
                     LNVPWDGRVQCRLTLPETVTLSRGPLLLPCR"
     gene            3367..4110
                     /locus_tag="OPV72_004133"
     CDS             3367..4110
                     /locus_tag="OPV72_004133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HCR9916284.1"
                     /translation="MKNSRRSRVILLALAAAWSQYSPAAVNVDRTRIIMDAPQKTVAI
                     TLNNDDKTTPFLAQSWVTDADGVRTDALIALPPLQRIDAGQKSQVRITQVRGLTDKLP
                     QDRETLFWFNVRGVPPKSEDDNVLQLAMQSQLKLFYRPKAIIRSSSDQPERKLTAERN
                     AGHLTLRNPTPYYITVAWLGADRSHRLSGFREGVMVPPLGSLPLKAVLPAETRTLWVG
                     YIDDYGGLQMNRYTCDALNCAFKDAGVTS"
     gene            4107..>4627
                     /locus_tag="OPV72_004134"
     CDS             4107..>4627
                     /locus_tag="OPV72_004134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916285.1"
                     /translation="MTEWIFNLKTKLTVLVMMLCSLCVTKVYAVEPGINECVVTSGQN
                     INLRSINLTTDDFKPGPDSVIYSINQDAVFKCSMGYGTQFPQLVFNQGYFSKFTQTLD
                     AMGLGFRMSVKETENVSNVVSFSWDEIKSTQSGNELRKEFGTKLPVGTTERKVRITLD
                     FLYTKAYSESSAVT"
BASE COUNT         1081 a         1288 c         1298 g          960 t
ORIGIN      
        1 aaagttcagg tgcttcgttt aacacccggc gtttattatt catgcgaatc ttttctgaac
       61 gctttcatta ataccctcag atttgttttc agcctttgca aaataattct cattcaccca
      121 aaggacatat tatctatgcg taataaaata atacttgcca tggcggctgc cggtatgatg
      181 tatggcgctt ctgtatatgc agtcgatcca ccaacagcag gcccgttcgg ctcaggtaaa
      241 attaccttta ctggtaccat caccaactcc ccctgtgata tcgcaccggg cgacgatgcg
      301 atcaccgttc catttggaca gatttcttac cgtaaactga ataccgccga tgcaaccacg
      361 gactcaaaac cgttcaccat tcatctgcag aactgtgctt tcgatccgaa tatcccggac
      421 acagctggct ccgcagggaa aatgtccaaa gtgaccgtct ctttctctgg cggagccaat
      481 gtcgcgaaaa aggcttacac caccagcggc agcgcacagc atgttggtgt ccagctactg
      541 aagagtgaca acaccgcaat tatcgagccc aacacccaga tgccggagga cgacgctcag
      601 caactgcagg ccggaaacaa cgaactcaac ttctatgccc ggctaatagc actggataat
      661 ggcgtcacgc ccggtgactt caccgcatct gtcacctaca ctctgaaata cctgtgattt
      721 tacgcggtaa ataacgacag ggagaagccg tccacggagg ggttcggacg gcttttatat
      781 ctgaccatgc ctgcgggctg tctgttacac ggacgacaac acgaaagcgc catgccatga
      841 aaattacccg gcttgccatt ctgattaccc tgacattttc cgtcctgaag tcgcaggcca
      901 cggagttcaa tgccagcctg ctggacagcg ggaacctgtc taacgtggac ctcacggcct
      961 tcagccgcga ggggtatgtg gcgcccggta actatattct cgatatctgg ctcaatgacc
     1021 agccggtacg ggaacagtat ccagtcaggg ttgtaccggt tgccggacgc gatgcggtcg
     1081 tcatctgtgt gacaacagac atggtggcca tgctgggtct taaggataag attattcatg
     1141 gcctgaaacc cgttaccggt atcccggacg ggcaatgcct tgagctgcgc tccgctgaca
     1201 gtcaggtacg gtacagcgct gaaaatcagc gtctgacctt cattattccc caggcctgga
     1261 tgcgttatca ggacccggac tgggtgcccc cttcacgctg gagcgacggc gtcaccgctg
     1321 gcctgcttga ttacagcctg atggtcaacc gctatatgcc gcagcagggg gaaacctcta
     1381 ccagctacag cctctacggc accgccgggt ttaatctcgg cgcctggcgg ttgcggagcg
     1441 attaccagta cagccgtttt gacagtgggc agggcgcatc acagtccgat ttttatctgc
     1501 cgcagacgta tctgttccgt gccctgccag cactgcgctc aaaactgacg ctcggacaga
     1561 cgtacctcag ctccgctatt tttgactcct tccgctttgc tgggctcact ttggccagcg
     1621 atgagcgcat gctgccgccc tctcttcagg ggtatgcccc gaaaattagc ggcattgcga
     1681 acagtaatgc acaggtcacc gtcagccaga atggtcgcat tctgtaccag acccgggtgt
     1741 caccggggcc ttttgagctt cccgacctga gccagaatat cagcggcaac ctggatgtca
     1801 gcgtccggga aagcgacggc agcgtccgga cctggcaggt caacacggct agcgtcccct
     1861 ttatggcacg ccagggacag gttcgctata aggtggccgc cggacgtccg ctgtacggcg
     1921 gtacgcataa caacagcacg gccagccctg actttctgct cggggaggcc acctggggag
     1981 catttaacaa cacgtcgctg tatggcggcc tcattgcctc caccggcgac taccagtccg
     2041 cggcgctcgg gatcggccag aatatggggc tgctgggcgc tctgtctgcg gacgtcaccc
     2101 gctcagatgc gcggttgccg cacgggcaga agcagtccgg ttacagctac cgtatcaact
     2161 atgccaaaac gtttgataaa accggcagta ccctggcgtt cgtcggatac cgcttctcgg
     2221 accgccattt tctgtccatg ccggagtacc tgcagcgtcg ggccaccgac ggcggcgatg
     2281 catggcatga aaaacagagc tacaccgtga cttatagcca gtccgttccg gtactcaaca
     2341 tgagcgcggc cctctcggta agccggctca attactggaa tgcgcagtcc aacaataact
     2401 acatgctcag cttcaacaaa gtgttcagtc tcggcgagct tcaggggctc tcggcctcgg
     2461 tgtcgtttgc ccgtaaccag tacaccggcg ggggcagcca gaatcaggtc tacgccacca
     2521 tcagtatccc gtggggcgac agccgccagg tgagctacag cgtgcagaag gataaccagg
     2581 gcggcctgca gcagaccgtg aattacagcg atttccataa cccggacacc acatggaaca
     2641 tcagcgccgg tcataaccgc tatgacaccg gcagtaacag cagcttcagc ggcagcgtgc
     2701 agagccgtct gccgtggggc caggcggcag cggacgccac cctgcagccc ggacagtacc
     2761 gcagcctggg cctgagctgg tacggctcgg tgaccgccac cgcccacggc gccgccttca
     2821 gccagtcgat ggccgggaat gagcctcgca tgatgataga taccggagac gtggccggtg
     2881 taccggtgaa cggcaacagc ggggtgacca accgcttcgg ggtgggcgtg gtgagcgccg
     2941 gcagcagcta tcggcgcagc gatatttcgg ttgatgtggc cgccctgcca gaggacgtgg
     3001 acgttagcag ctccgtcatc agccaggtgc tgacggaggg cgcggtgggc taccggaaga
     3061 ttgacgccag ccagggggag caggtgctcg gtcatatccg gctggctgat ggcgccagtc
     3121 caccgtttgg cgccctggtg gtgtccggaa aaaccggcag aaccgcgggg atggtcgggg
     3181 atgacggtct ggcctacctg accggactca gcggggaaga ccgccggacc ctgaacgtgc
     3241 cctgggatgg ccgggtgcag tgcagactca ccctgccgga aacggtgaca ctcagtcggg
     3301 ggccgctgtt actgccctgc agataaaaat atccctgtca cagagcagga ctaacggaga
     3361 aaacaggtga aaaacagcag aagaagccgt gtgattttac tcgcactggc ggcagcatgg
     3421 agccagtaca gcccggcagc cgtcaatgtc gaccggaccc gtattatcat ggatgcaccg
     3481 cagaaaacgg tggccatcac gctgaataac gatgacaaaa ccacgccgtt cctggcgcag
     3541 tcctgggtga cggacgctga cggggtgaga acggatgcgc tgatagcgct gccaccgctg
     3601 cagcgtattg atgccggaca gaaatcccag gtccgtatca cccaggttcg cgggctgaca
     3661 gacaagctcc ctcaggacag ggaaacgctg ttctggttta acgtgcgggg cgttcccccg
     3721 aagtcagaag acgacaacgt cctgcaactg gccatgcaga gccagctgaa actgttttac
     3781 cgtccgaaag ccattatcag aagcagcagt gaccagccgg aaagaaagct gactgctgag
     3841 cggaatgcgg gacatctgac cctcagaaac ccgacgccgt actacatcac tgtggcgtgg
     3901 ctgggagcag accgcagcca caggctcagc ggtttccgcg agggcgtgat ggtgccgccc
     3961 ctggggagcc tgcccttaaa ggctgttctg ccggcagaaa cccggacgct gtgggtgggg
     4021 tatatagatg attatggtgg actgcagatg aaccgctaca cctgtgatgc cctgaactgc
     4081 gcgtttaagg acgcaggggt gacatcatga cagaatggat ttttaatctg aaaacaaaac
     4141 tgaccgtgct ggtgatgatg ttgtgttctt tatgtgtgac taaagtgtat gcggttgagc
     4201 caggtataaa tgaatgtgta gtcacttctg gtcagaatat taatttaaga agtataaatt
     4261 tgacaaccga tgattttaaa cctggcccgg attcggttat ctattcaatc aatcaggatg
     4321 cagttttcaa atgttcaatg ggatatggca cgcaatttcc acagctggta tttaatcagg
     4381 gctacttcag taaatttacc cagacactag atgcgatggg acttggattc agaatgtccg
     4441 ttaaagaaac agaaaatgtt tcaaatgttg tttcgttctc ctgggatgaa ataaagagca
     4501 ctcagtcagg aaatgagtta cgaaaagagt ttggcacaaa actacctgtt ggaactacag
     4561 agcgaaaagt aaggataaca ctggatttct tatatacaaa agcatattca gagagtagtg
     4621 cagttac
//
LOCUS       DAJVBX010000253         4623 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.253, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000253 DAJVBX010000000
VERSION     DAJVBX010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4623)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4623)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4623
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.253"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            45..752
                     /locus_tag="OPV72_004135"
     CDS             45..752
                     /locus_tag="OPV72_004135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001748430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HCR9916286.1"
                     /translation="MRYFFMAEPIRAMEGDLLGVEITTHFASSPARPLHPEFVISSWD
                     NSQKRRFLLDLLRTIAAKHGWFLRHGLFCIVNIDRGMAQLVLQDKDIRALLHAMLFVE
                     LQVAEHFSCQDNALIDPLIHALHKQPNPLWLGDLGVGNATAAPLVCGCFSGVKLDRSF
                     FISQIEKMTFPLLVKHIRRYCDKIVVGGQENTRYLPALKTAGIWATQGTLFPSVALEE
                     VETLLLGRRVNTLRESN"
     gene            complement(768..1574)
                     /gene="sapF"
                     /locus_tag="OPV72_004136"
     CDS             complement(768..1574)
                     /gene="sapF"
                     /locus_tag="OPV72_004136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter ATP-binding protein
                     SapF"
                     /protein_id="HCR9916287.1"
                     /translation="MVETLLEVRNLSKTFRYRTGWFRRQTVDAVKPLSFTLRERQTLA
                     IIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHYGDYSFRSQRIRMIFQDPSTSLN
                     PRQRISQILDFPLRLNTVLEPEQRRKQIVETMRMVGLLPDHVSYYPHMLAPGQKQRLG
                     LARALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGISYIYVTQHIGMMKHIS
                     DQVLVMHQGVVVERGSTADVLASPLHELTRRLIAGHFGEALTADAWRKDR"
     gene            complement(1576..2568)
                     /gene="sapD"
                     /locus_tag="OPV72_004137"
     CDS             complement(1576..2568)
                     /gene="sapD"
                     /locus_tag="OPV72_004137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter ATP-binding protein
                     SapD"
                     /protein_id="HCR9916288.1"
                     /translation="MPLLDIRNLTIEFKTSEGWVKAVDRVSMTLSEGEIRGLVGESGS
                     GKSLIAKAICGVAKDNWRVTADRMRFDDIDLLRLSSRERRKLVGHNVSMIFQEPQSCL
                     DPSERVGRQLMQNIPAWTYKGRWWQRLGWRKRRAIELLHRVGIKDHKDAMRSFPYELT
                     DGECQKVMIAIALANQPRLLIADEPTNSMEPTTQAQIFRLLTRLNQNSNTTILLISHD
                     LQMLSQWADKINVLYCGQTVETAPSKDLVTTPHHPYTQALIRAIPDFGSAMPHKSRLN
                     TLPGAIPLLEQLPIGCRLGPRCPYAQRECIITPRLTGAKNHLYACHFPLNMERE"
     gene            complement(2568..3458)
                     /gene="sapC"
                     /locus_tag="OPV72_004138"
     CDS             complement(2568..3458)
                     /gene="sapC"
                     /locus_tag="OPV72_004138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter permease SapC"
                     /protein_id="HCR9916289.1"
                     /translation="MPYDSVYSEKRPPGTLRTAWRKFYSDAPAMVGLYGCAGLALLCI
                     FGGWIAPYGIDQQFLGYQLLPPSWSRYGEVSFFLGTDDLGRDVLSRLLSGAAPTVGGA
                     FIVTLAATLCGLVLGVVAGATHGLRSAVLNHILDTLLSIPSLLLAIIVVAFAGPHLSH
                     AMFAVWLALLPRMVRSVYSMVHDELEKEYVIAARLDGATTLNILWFAILPNITAGLVT
                     EITRALSMAILDIAALGFLDLGAQLPSPEWGAMLGDALELIYVAPWTVMLPGAAITLS
                     VLLVNLLGDGIRRAIIAGVE"
     gene            3593..3994
                     /locus_tag="OPV72_004139"
     CDS             3593..3994
                     /locus_tag="OPV72_004139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001543117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4102 domain-containing protein"
                     /protein_id="HCR9916290.1"
                     /translation="MYTQMCISSYGVYTLLADTKLRKAPGKKRDQIKVISDAHGLNVR
                     LSTSGSITFFYRYRWNGNAAQLTIGDYPTISLSHARERRQYFRSWLTEGLDPRRQMVL
                     EKKKKTEALTVKEHTTTGRSFSTVRNLGQGH"
     gene            complement(4268..>4623)
                     /locus_tag="OPV72_004140"
     CDS             complement(4268..>4623)
                     /locus_tag="OPV72_004140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916291.1"
                     /translation="QKSGFLLVTGEKGFNKSACLHMLGQQISRVFSGKHLYPGVFISK
                     DAASEFEKTISTYYKTLSGHIDLQQYTNDVNCGAAVGIVARQQENLILDEITLSTFKK
                     VYVRFLRYCKLTVTV"
BASE COUNT         1156 a         1143 c         1180 g         1144 t
ORIGIN      
        1 taaaagcgca ttatcaggga gttaagatca agtggagtgg tcacatgcgc tattttttta
       61 tggcagagcc gataagggca atggaggggg atttactggg tgtcgaaatc actacccatt
      121 ttgcatcgtc gcccgctcgt ccgctacacc ctgagtttgt tatctcgtca tgggacaatt
      181 cgcagaagcg ccgttttctg cttgatctgt tgcggacaat cgcggccaaa catggctggt
      241 ttctacgcca cggcctgttc tgtatcgtaa atatcgatcg gggtatggcg cagcttgtcc
      301 ttcaggacaa agatattcgc gcattactac acgccatgct atttgtggag ttgcaggtcg
      361 ctgaacattt ttcatgtcaa gataacgcct taatcgatcc tttaatacac gcgcttcata
      421 agcaacctaa tccattatgg ctgggcgacc tgggcgtagg gaacgcaacc gctgcgccat
      481 tagtttgcgg gtgttttagc ggcgtaaaac ttgatcgcag cttttttatc tcacaaattg
      541 aaaaaatgac gtttccgctg cttgtcaaac atatccggcg ttattgtgac aagatcgtgg
      601 tgggtggcca ggaaaacaca cgctatttgc cggcgttaaa aacggcaggc atttgggcaa
      661 cccagggcac gttatttcct tccgttgcgt tagaagaggt tgaaacattg ctgttgggcc
      721 gtcgcgtgaa caccctcaga gaatcgaact gagggtattt gtgtcgctta gcgatccttt
      781 cgccatgcgt cagcggtcag cgcctcgcca aaatggcctg cgattaaacg gcgggtaagc
      841 tcatgtagcg gagaggcgag cacatcggcg gtgctgccgc gttcaaccac taccccctga
      901 tgcatcacta atacctgatc gctaatatgt ttcatcatgc cgatatgctg cgtgacgtag
      961 atataggaga tgccttgttt ttcctgcaat tcaagcatca gattgatgag ctgcgagcgc
     1021 atggacatat caagcgaagc cagcgcttcg tccgcgataa tgacttttgg gcgtaaaatc
     1081 agcgcgcggg ccagacccag acgttgtttc tgtcccggcg ccagcatatg cgggtagtag
     1141 ctcacgtgat cgggcaatag ccccaccata cgcatcgtct cgacaatctg tttgcgccgc
     1201 tgttccggct ccagaacggt attaaggcgc agggggaagt caagaatctg tgaaatacgt
     1261 tgacgtggat tcagtgacgt tgaagggtcc tgaaaaatca ttcgaatacg ttggcttcga
     1321 aacgaatagt cgccgtaatg caggggatga tcgtcaataa gaagctcgcc gctggtgggt
     1381 tcaatcatgc cggccagcat ctttgccaac gtggatttgc cggaaccgtt ttcgccgata
     1441 atggccaggg tctgacgctc acgaagcgta aagcttaatg gtttcacggc gtcgacggtc
     1501 tggcggcgaa accatcctgt tcggtagcga aaggttttac tcaggttgcg cacttcaagc
     1561 agagtttcca ccatatcact ctctctccat attcagcgga aaatgacagg catagagatg
     1621 atttttcgcg ccggttaagc gtggcgtgat aatgcattct cgttgcgcgt aagggcagcg
     1681 cggccccaga cgacaaccta tcggtaactg ctccagtagc gggatcgcgc ccggcagcgt
     1741 attcagacgg cttttatgcg gcatcgcgct gccaaaatcc ggaatcgcac ggataagcgc
     1801 ctgcgtataa ggatgatgtg gtgtcgtcac cagatcttta cttggcgcgg tttctaccgt
     1861 ctggccgcag tataagacgt tgattttgtc agcccactga ctcagcattt gcaggtcgtg
     1921 gctaatcaac agaatggtgg tattactgtt ttgattcagt cgcgtcaaca ggcgaaaaat
     1981 ttgcgcctgc gtcgtcggtt ccattgagtt ggtgggttca tcagcgatca ggagtcgcgg
     2041 ttgattcgcc agcgcgatag cgatcataac tttctgacac tcgccatcgg ttagttcata
     2101 gggaaaactg cgcatcgcgt ctttatgatc tttaattccc acccggtgca gtaattcaat
     2161 tgcacgccgt ttacgccagc ctaaacgctg ccaccagcgg cctttatagg tccaggcggg
     2221 aatattttgc attaactggc ggccgacgcg ttcggaagga tcaaggcacg actgcggctc
     2281 ctggaagatc atcgacacat tatgcccgac cagcttacgc cgttcacgag aggagaggcg
     2341 cagcagatcg atatcatcaa aacgcatacg gtcggcagtg actcgccagt tgtctttcgc
     2401 gacgccgcaa atagctttag caatcaagct ctttccggaa cccgattcac ctaccaggcc
     2461 gcgaatttca ccttcgctta atgtcatact gacgcgatcg accgctttta cccaaccttc
     2521 gctggtttta aattcaatgg tgagattgcg gatatccagt aacggcatta ttccaccccc
     2581 gcaataatcg cacgacgaat cccatctccg agcaggttta ccagtaaaac actgagcgtt
     2641 atcgccgcgc cgggtagcat aacggtccac ggcgcgacat agattaactc cagcgcatcc
     2701 cccaacatgg cgccccattc aggagaggga agctgcgcgc cgagatctaa aaatcccagc
     2761 gcggcgatgt ccagaatcgc catcgacagc gcccgggtaa tttcggtgac cagaccggcg
     2821 gtaatattcg gtaaaatggc gaaccacaga atattcagtg ttgtcgcgcc atccagacgg
     2881 gcagcaatga cgtactcttt ttccagttca tcatgcacca tgctatagac ggaacgtacc
     2941 attcgcggca acagggccag ccagacggca aacatcgcgt gtgacagatg tgggccggca
     3001 aatgccacaa cgataatcgc cagcaagagc gaagggatgg aaagcagcgt gtccagaata
     3061 tggttcagta cggcagagcg taaaccgtgg gtcgcgcctg ccactacgcc gaggactaat
     3121 ccacatagcg tagccgccag cgttacgata aacgcgccgc cgaccgtggg cgccgcgccg
     3181 cttaacaggc ggctcagcac atcgcgcccc agatcgtcag tccccagaaa aaaggagact
     3241 tcgccatagc gtgaccagga gggtggcagt agctgatagc ccagaaattg ctgatcgata
     3301 ccatagggcg cgatccagcc gccaaaaata cacagcaacg ccagaccggc gcatccatac
     3361 agacccacca tcgcaggcgc gtcgctataa aatttacgcc aggcagtgcg cagggtgcct
     3421 ggcgggcgct tttcgctgta gacgctatcg taaggcatat ttactcgttt tatttttgtt
     3481 taccatgctt tatgtctttt gaaattttca agcactatca attggttatg gattgtaagc
     3541 gtctcaattt tgtgtacttt gcattaatgt gaaggttatc aatttatgca aaatgtatac
     3601 acagatgtgt atatcctctt atggagtgta cacattgctt gccgatacaa aattaagaaa
     3661 ggctcctggc aaaaaaagag accaaatcaa ggtcatctca gacgctcatg gtctcaatgt
     3721 caggctctct acatccggca gtataacatt cttttaccga tacagatgga acgggaacgc
     3781 tgctcaactg acgattggcg attatccaac catatcacta tctcatgcca gggaacgccg
     3841 tcagtacttt agatcatggt taactgaggg actcgatcct cgtcgccaga tggtgctgga
     3901 gaagaagaaa aaaacagaag cgttaaccgt aaaagaacat acgactactg ggagaagttt
     3961 tagcactgta cggaatttgg gccagggtca ttaagaccga cagtggcgtc tggcactagt
     4021 ttgaagtatg gcgcgatcag gatgttgcag tatttgtaga agcggcgcgc ggcggcatcc
     4081 ggggaatagt ccggcttaaa gtatctggcg gagtttgtgt tcagttgcgg cattagtctt
     4141 tgggaggttc acaataagac agatcggaat actccggcat gaggtgttgc gtcttaaact
     4201 gctgcagcgg gtcagcaggg ggaatgatat ttattagctc agatgtgagc tgacagttac
     4261 cgattattta tacagtaact gtcagtttac aatatcgtaa aaacctaaca tagacctttt
     4321 taaacgtact taatgtgatc tcatctagta tgaggttttc ttgctgccgt gcaacaatac
     4381 ctacagctgc tccgcaattt acatcattag tgtattgttg cagatcaatg tgacccgaaa
     4441 gagttttata ataagtgctg attgtttttt caaattcgga cgctgcgtct ttacttataa
     4501 aaacaccagg atataagtgc ttcccagaaa aaactctgga tatttgttgt cccagcatat
     4561 gcaggcaagc agatttgttg aagcctttct ctcccgttac taacaagaaa ccactttttt
     4621 gct
//
LOCUS       DAJVBX010000254         4604 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.254, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000254 DAJVBX010000000
VERSION     DAJVBX010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4604
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.254"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            26..538
                     /locus_tag="OPV72_004141"
     CDS             26..538
                     /locus_tag="OPV72_004141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001727965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CaiF/GrlA family transcriptional regulator"
                     /protein_id="HCR9916292.1"
                     /translation="MCPDNTHAKKQYLIPGNDIHYPGQTNHDACFIPVSVRQYAGEPL
                     YIIVAHWCLLQQNWVQRNQIAEAFHITARRASYLIAYLRSKTSRVVSICRHQTLPNKA
                     RRYEIYVIRVLDSPTPSTRREKAGPPPVSKRRVGNGDRSMANELWNRLCSNRNAGKIL
                     KKREDEDDRT"
     gene            525..1283
                     /locus_tag="OPV72_004142"
     CDS             525..1283
                     /locus_tag="OPV72_004142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCR9916293.1"
                     /translation="MTEHNRIPARQIIVYGDCWPVTIAVAHLVRRFLPGCNCETAYRL
                     PVLLQQLRRKPEAILILCLRPREHLFLFYSLRQILPDYPVMIISDELFFSDRVVLKVY
                     GGIPALLEQELAEILIRWRRDEQWAGGARLRRTGGLDAFLLSPDPVTGFLEVPPIFNN
                     PKRLMNYMDQLMHREILACGVSLAQLRLLQEVYRGRGRLSALCGRLNTQEKQIWQDKY
                     RLLVKLGMRNRLRELLFGTRFCKSLQRTPFIAPQ"
     gene            complement(1493..2359)
                     /locus_tag="OPV72_004143"
                     /pseudo
     CDS             complement(1493..2359)
                     /locus_tag="OPV72_004143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461941.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nickel/cobalt efflux protein RcnA"
     gene            2481..2753
                     /gene="rcnR"
                     /locus_tag="OPV72_004144"
     CDS             2481..2753
                     /gene="rcnR"
                     /locus_tag="OPV72_004144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni(II)/Co(II)-binding transcriptional repressor
                     RcnR"
                     /protein_id="HCR9916294.1"
                     /translation="MSHTIRDKQKLKARTSKIQGQVIALKKMLDEPHECAAVLQQIAA
                     IRGAVNGLMREVIKGHLTEHIVHQSDEARREEDLDVILKVLDSYIK"
     gene            complement(2784..4013)
                     /locus_tag="OPV72_004145"
     CDS             complement(2784..4013)
                     /locus_tag="OPV72_004145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HCR9916295.1"
                     /translation="MSKIWSKDETLWSFALYGTAVGAGTLFLPIQLGSAGAIVLFITA
                     LVAWPLTYWPHKALCQFILSSKTSAGEGITGAVTHYYGKKIGSIITTLYFIAFFVVVL
                     IYAVAITNSLTEQLAKHIQIDIRIRMAVSFGVVLILNMIFLMGRHATLRVMGFLVFPL
                     IAYFLFLSLYLTGSWQPSLLTGQMSLDSHTLHQVWISIPVMVFAFSHTPIISTFAIDR
                     RENFGDQAMDKCKKIMKVAYLIICLSVLFFVFSCLLSIPPSYIEDARNEGVTILSALS
                     MMPNAPAWLSISGIIVAVVAMSKSFLGTYFGVIEGATEMVRTTLQQVGVKKSRAFNRA
                     LSIMLVSGITFIICCINPNAISMIYAISGPLIAMILFIMPTLSTYLIPALKPYRSIGN
                     FITLVVGLLCVSVMFFG"
     gene            complement(4155..4595)
                     /locus_tag="OPV72_004146"
     CDS             complement(4155..4595)
                     /locus_tag="OPV72_004146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001163400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug/biocide efflux PACE transporter"
                     /protein_id="HCR9916296.1"
                     /translation="MQRRSLPERIFHAVCFEGIATAILAPTTAWLMQRSVLEMGGLTI
                     LLATTAMIWNIIYNALFDRLWPAHQVRRTAKVRALHALGFESGFIVIGVSIVAWVLNV
                     SLLQAFTLEIGFFLFFLPYTMLYNWAYDVLRQRIVTRRQQRVSA"
BASE COUNT         1258 a         1112 c         1212 g         1022 t
ORIGIN      
        1 atttacccag ttatggagag gttttatgtg ccctgataat acacacgcaa aaaagcagta
       61 ccttatccca ggtaacgata ttcattatcc cggacagacc aaccatgatg cctgttttat
      121 tccggtaagt gtccgccagt atgccggcga gcccctgtat atcatcgtgg cacactggtg
      181 cctgttgcag cagaactggg ttcagcgtaa ccagatagca gaggcgtttc acatcacggc
      241 cagacgggcc agctacctga ttgcctatct gcgaagcaaa acatcgcggg tggtcagcat
      301 ctgccgtcac cagaccctgc ccaataaagc acgacgctat gagatttatg ttatccgggt
      361 tcttgacagt cccaccccgt ccacgcgccg tgaaaaagcc ggaccgccgc cggtatcaaa
      421 acgccgggtc ggtaatggtg acaggtcgat ggcaaatgaa ctgtggaacc ggctgtgcag
      481 taacagaaat gcgggaaaga tcctgaaaaa gagggaggat gaggatgaca gaacataacc
      541 ggataccggc ccggcagatt atcgtttacg gtgactgctg gccggtgacg atcgccgtgg
      601 cacacctggt ccggagattt ctgccgggct gcaactgtga aaccgcatac aggctgcctg
      661 ttctgttgca gcaattacgt cggaaaccgg aggccatact gatactgtgt ctgcgtcccc
      721 gtgaacatct ctttttgttc tattccctga ggcagatact gccggactac ccggttatga
      781 ttatcagcga tgagctgttt ttcagcgacc gggtggtact gaaggtatac ggcggcatcc
      841 cggcgctgct ggagcaggaa ctggcggaga tacttattcg gtggcggcgg gatgaacagt
      901 gggccggggg cgcacgcctg cgcaggacag gagggctgga cgcctttttg ttatctccgg
      961 atccggtgac gggctttctg gaagtgccac cgatatttaa caatccgaag cggttgatga
     1021 actatatgga ccagttgatg caccgggaga tactggcatg cggagtgagc ctggcccagt
     1081 tacgcttgct tcaggaagtt taccgtggac ggggaaggtt atcagcgctg tgtggaaggc
     1141 tgaacacgca ggagaagcaa atctggcagg acaaataccg gttactggtg aagctgggaa
     1201 tgcggaaccg attacgggaa ctgctgtttg gtacccggtt ttgtaaatca ctgcagcgaa
     1261 ctccgtttat cgctccgcaa taacccgcct ccggcgaccc tatccagaaa cactgacaca
     1321 ccggctaaac ccggtggcgg tggggtatgt tttgcctgtg gtgtagtgga gtaaaataca
     1381 gaattcaggc gggacgctga atgtatggcc tttcataccg tttgataagt aaaaacgctt
     1441 ctggaatgaa acccgaagtg aatgatacgg cctgagcaga agcgttacat atttactgca
     1501 tgatcccggt atagccatga attcccatat acacgccgac cagaccaatc agaatgctcg
     1561 aaaaataggg cgcccgccgg gcaagcgtcg aaaaaccact ccagcgcttt gctgcctgtt
     1621 gaacgcttat cgccgcgcca acgcctaccg tcaccagcgt taatgccagg ccaagactaa
     1681 agctcagcac catcgtggca cccagcgtaa acgctttaag ctggatacaa atcagtaaaa
     1741 cggtgatcgc agccggacag gggataagcc ctccggtcag gccgaacagc aggatctgtc
     1801 cattattcac tgtttgacca tcaaaacggc gttgaatatc ggcagcatgg gcgcgttcat
     1861 gggcatcctg atacgctttt gacgttgcgc cttccggatg tatgtgacca tgatggtcat
     1921 ggtcatggtc atggtcatgg tcatggtcat ggtcatggtc atggtcgtaa tggtggtcgt
     1981 gatggtggtc gtgatggtgg tttcccgcca gccactgctg ctcgcctcgt catgtccgcc
     2041 agaacatcca gcacgcggtg ctcagaataa tgatcgcaga aattaactgc agccatggtt
     2101 ccactgattg tgcggtgaat gcccggctaa gatacatccc acccagcgcg attaaccaga
     2161 cgatcgcggt atgagaaagc gttgctgcca gaccgagcat gacagcctgt ttaaccgtac
     2221 ctttaatggc aatgataaaa gccgccatca tggttttgga gtgccctggt tcaagcccgt
     2281 gcaaaatacc taataaaatg gcgctgggaa tgaagaacca gccgtttcct tgctgaagaa
     2341 gtgtcgaaaa ttcacccatg agaatgattc ttagttgttt tatgtgggcg tcattctact
     2401 cccccccagt atggaatact accccccagt agcatcgtaa tgctataatt tgtattcgtt
     2461 aatgttagtg aggtgttgta atgtcacata ccatccggga caaacaaaag cttaaagcca
     2521 gaaccagcaa gattcagggg caggtgatag cgctaaaaaa aatgctggat gaaccgcatg
     2581 aatgcgcggc cgtgttacaa cagatcgcgg cgattcgcgg cgcggtaaat ggcttaatgc
     2641 gcgaggtgat taaagggcat ctgaccgagc atatcgttca tcagagtgat gaagccagac
     2701 gtgaagaaga tctggacgta atattaaagg tgctggattc ttatataaaa tagccgggag
     2761 ttatatcccg gctatctttt actttagccg aaaaacatca ccgatacgca aagtaaaccg
     2821 acgaccaacg taatgaaatt acctattgaa cggtagggtt tcaatgccgg tatcaggtac
     2881 gttgacaacg tgggcataat aaacagaatc atcgcaatga gcgggccgct aatggcataa
     2941 atcatagaga tggcattcgg gttaatacag caaataataa acgtaatccc ggaaaccagc
     3001 atgatagaca gcgcgcgatt gaacgcccgg ctttttttca cgccaacctg ctgtagggtg
     3061 gttcttacca tttcggttgc gccctcgatg acgccgaaat aggtgccgag gaaagatttc
     3121 gacatggcca cgacggcaac gataataccg gaaatagaga gccaggccgg cgcattgggc
     3181 atcatcgaga gcgcggaaag gatggtaacg ccttcgttgc gcgcgtcttc aatgtatgac
     3241 ggcggaatgg agagcaggca gctaaagaca aagaacagca cactcaggca gataatcagg
     3301 taggcgacct tcatgatctt tttgcattta tccatggcct gatcgccaaa attttcccgt
     3361 ctgtcgatgg caaacgtcga aataatgggc gtatggctaa aagcaaaaac catcaccgga
     3421 atagaaatcc atacctggtg caacgtgtga ctatccaaag acatctgccc ggtcagtaac
     3481 gagggttgcc agcttccggt taagtagagc gaaaggaaca agaagtaagc gataagtgga
     3541 aagactaaaa agcccattac gcgaagagtg gcatgtcttc ccattaagaa aatcatattc
     3601 aggataagta ctacgccgaa gctaactgcc atccggatgc gaatatctat ctgaatatgc
     3661 ttcgctaatt gctctgtcag ggaattggta atcgccacag cataaattaa taccacgaca
     3721 aaaaacgcaa tgaaataaag cgtggtaata atactgccga ttttcttgcc gtaataatga
     3781 gtaacggcgc cagtaattcc ctcacctgca gaagtctttg aggaaagaat aaactgacac
     3841 agcgccttat gcggccagta tgttagaggc caggcgacca gcgcggtaat aaatagcacg
     3901 attgcgcctg ccgatcccaa ctggatggga aggaaaagag tgcctgcgcc tacagccgtt
     3961 ccgtataatg caaaactcca gagagtctca tcttttgacc aaattttaga cattatttga
     4021 atttatcaac tataaaacac acaaaaagaa gcgcaattta ccataaatag cgtcagttgg
     4081 gggcgtttta agcagatgga tgtcgtggag gaggagggcc gggagcgttg cgatcccggc
     4141 aaaaaagagc aatatcatgc actaacgcgc tgttggcggc gggtcactat tcgttggcgt
     4201 aaaacatcgt atgcccagtt gtacagcatc gtgtacggca aaaagaacag gaagaaacca
     4261 atttccaggg tgaatgcttg tagcaggctg acattcagta cccaggcgac aatactcacg
     4321 ccaatgacaa taaacccact ttcaaatcct aacgcatgga gtgcgcgcac tttggcggtt
     4381 cgtctcacct gatgcgcagg ccacagtcga tcaaacagag cgttataaat gatattccag
     4441 atcatggccg tcgttgccag caatatcgtc aggccgccca tctccagcac cgagcgctgc
     4501 attagccagg cggtcgttgg cgccagtatc gcagtcgcaa taccttcaaa acagacagca
     4561 tggaaaatac gctccggcag cgagcgacgt tgtatggcgt catg
//
LOCUS       DAJVBX010000255         4537 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.255, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000255 DAJVBX010000000
VERSION     DAJVBX010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4537
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.255"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            4..477
                     /locus_tag="OPV72_004147"
     CDS             4..477
                     /locus_tag="OPV72_004147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001664988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCR9916297.1"
                     /translation="MHRITTADNAAIARVIRQVSAEYGLTADKGYTVADPNLDELYQV
                     YSQPGAAYWVVEQNGCVVGGGGVAPLSCSEPDICELQKMYFLPVIRGQGLAKKLALMA
                     LDHAREQGFKRCYLETTAFLREAIALYERLGFEHISEPLGCTGHVDCEVRMLKDL"
     gene            584..1072
                     /locus_tag="OPV72_004148"
     CDS             584..1072
                     /locus_tag="OPV72_004148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3617 domain-containing protein"
                     /protein_id="HCR9916298.1"
                     /translation="MKRLLSAIVFPAMFISISNVYALDIQPGEWKMENIEMRTINPDT
                     KEVLMDEKNSGIATLMCYTPKMSEDSKKMVKGFSTSAGGCTTTFVESTDTKLINETVC
                     NNPDVKSHSIVETTKISDTEFAMTMKSDVDAGGNKTTSINKIKQTFVGKTCSEASKGV
                     KQ"
     gene            complement(1317..2081)
                     /gene="miaE"
                     /locus_tag="OPV72_004149"
     CDS             complement(1317..2081)
                     /gene="miaE"
                     /locus_tag="OPV72_004149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA isopentenyl-2-thiomethyl-A-37 hydroxylase
                     MiaE"
                     /protein_id="HCR9916299.1"
                     /translation="MNYPQILSPVLNFLHCPTPQAWIVQARDPQNLPLLLTDHLICEL
                     KAAQTALLLVRKYVADKSGADALLAWLQPYEAFAFRQGPEPDFVALHKQISKSAMPQT
                     DDPWGRQLIDRMVLLIKEELHHFWQVREVMQARNIPYVKITASRYAKGMLKAVRTHEP
                     LTLIDKLICGAYIEARSCERFAALAPWLDEDLQTFYLSLLRSEARHYQDYLALAQQIS
                     AEDISARVRYFGDVEADLILSPDREFRFHSGVPAAG"
     gene            complement(2140..2556)
                     /gene="rraB"
                     /locus_tag="OPV72_004150"
     CDS             complement(2140..2556)
                     /gene="rraB"
                     /locus_tag="OPV72_004150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease E inhibitor RraB"
                     /protein_id="HCR9916300.1"
                     /translation="MANPELLEEQREETRLIIEELLEDGSDPDALYTIEHHLSADDFE
                     TLEKAAVEAFKLGYEVTEPEELEVEEGDTVICCDILSECALNAELIDAQVEQLMNLAE
                     KYDVEYDGWGTYFEDPNGEEGDDDDYVDEDDDGVRH"
     gene            2722..3726
                     /gene="argF"
                     /locus_tag="OPV72_004151"
     CDS             2722..3726
                     /gene="argF"
                     /locus_tag="OPV72_004151"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HCR9916301.1"
                     /translation="MSTFYQKPFLKLLDFTASELTALLQLAAKLKADKKNGKEEQKLV
                     GKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGSSGSQIGHKESIKDTARVLGRMFD
                     GIQYRGYGQEIVETLAEYSGVPVWNGLTDEYHPTQLLADLLTMQEHLPGKAFNEMTLV
                     YAGDARNNMGNSMLEAAALTGLDLRLVAPKACWPQAALVAECSAMAKKNGGAITLTED
                     IASGVKGADFIYTDVWVSMGEPKEKWAERIALLRDYQVNSQMMALTGNPQVKFLHCLP
                     AFHDDETTLGKKMAEEYGLHGGMEVTDEVFESAASIAFDEAENRMHTIKAVMVATLSK
                     "
     gene            complement(3800..4252)
                     /locus_tag="OPV72_004152"
     CDS             complement(3800..4252)
                     /locus_tag="OPV72_004152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HCR9916302.1"
                     /translation="MIVGNIEHLEAWLPTALRQAIEHVNAHVTATTAPGKYDIDGDRL
                     FYMISENMTEPGESRSAEYHARYLDIQIVLQGQEGMAFSTRPAGTPHTDWLADKDIAF
                     LPTSVDEKTVVLNEGDFVVFYPGEVHKPLCAVGEPARVRKAVVKMLMA"
BASE COUNT         1192 a         1134 c         1102 g         1109 t
ORIGIN      
        1 acggtgcacc gaatcactac cgccgacaat gccgctattg cccgtgtcat ccgtcaggtt
       61 tcagcggaat acggacttac cgccgataaa ggttataccg ttgccgaccc caatctggat
      121 gaactgtatc aggtttatag ccaaccgggc gcggcctact gggtggtaga gcaaaacggt
      181 tgtgtggtgg gcggcggcgg cgtggcgccg ttatcctgta gcgaaccaga catttgtgaa
      241 ctgcaaaaaa tgtatttttt accggtaatt cgtggtcagg ggctggcgaa aaagctggcg
      301 ctgatggcgc tggatcatgc ccgtgaacag ggttttaaac gctgctatct ggaaacaacg
      361 gcttttttac gcgaggcgat tgcgctatac gaacgtttag gatttgaaca tattagcgaa
      421 ccgctcggct gcaccggaca tgtcgattgc gaagtgagga tgttaaagga tctctgaaaa
      481 ccaggcgttt atttatcctc gccaggtatt atttttgctg atataagtaa tcccggaaac
      541 atcctgttat ccgggaatca cttattattc aaggaagtta taaatgaaac gcctattatc
      601 agcaattgtt ttccccgcta tgtttattag tatctctaat gtatatgcat tagatataca
      661 gcccggcgaa tggaaaatgg aaaatataga aatgcgcacc atcaatccag atacaaaaga
      721 agtattaatg gatgaaaaaa attcgggcat agcgacgctt atgtgttata cccctaaaat
      781 gtctgaagat tctaaaaaaa tggtgaaggg tttttctacc agtgcaggcg gttgcacgac
      841 aacatttgta gaaagtacgg ataccaaact gatcaatgag actgtgtgta ataatcctga
      901 tgtcaaatcg cactctattg tagaaacgac gaaaataagc gatacagaat ttgcgatgac
      961 catgaaatcg gatgtcgatg caggaggtaa taaaacaacc tccatcaaca aaattaaaca
     1021 aacctttgtt ggcaagacct gctctgaagc gtcaaaaggc gtgaaacagt aactatttca
     1081 acacaaaaac ccgtagtgat tgatgcaata atggcattgt tcacggtcac ctttcgggaa
     1141 tataacactg agtgagttct ttttgcctgc cgcagggcag gctttactca ggacagaata
     1201 tcatgaaaat gacttttcct gctcgccagc agcttgatgc cgggcggatg accaccacaa
     1261 attttgcaga cggcgacagc gtaaaagata aaaacgctaa tctttaattt tacgctttat
     1321 ccggcggctg gcacgccgct atgaaaacga aactcgcggt ctggcgacaa gataaggtca
     1381 gcttccacgt cgccaaaata gcgcacgcgc gcagaaatgt cctcggcgga aatctgctgc
     1441 gccagcgcca ggtaatcctg ataatgccgc gcttcggagc gcagaagcga gagataaaac
     1501 gtctgtaaat cctcatccag ccagggggcc agagcggcaa aacgttcgca ggagcgggct
     1561 tcgatatacg ccccgcaaat cagcttatca attaaggtga gcggttcgtg cgtgcgtacc
     1621 gctttcaaca ttccttttgc gtagcggctg gcggtgattt tcacataagg aatgtttctg
     1681 gcctgcatga cctcgcgtac ctgccaaaaa tggtgcaact cctctttaat caataacacc
     1741 atacggtcga taagctgacg accccagggg tcatcagttt gcggcatggc gcttttgcta
     1801 atctgtttat gcagggcaac aaaatccggc tccggcccct gacgaaacgc gaacgcctcg
     1861 taaggttgca gccaggcgag cagcgcgtcg gcgcccgatt tatcggcgac atatttacgc
     1921 accaacagca acgcggtttg cgcagccttc agttcgcaga tcaagtgatc ggtaagcaga
     1981 agaggaagat tttgcggatc gcgggcctgg acaatccacg cctgcggcgt cgggcaatgc
     2041 aggaaattaa gcaccggaga gagtatttgc gggtaattca tacgtaacct gtaaaaaaat
     2101 acgacagcag acgctgccgt accgtcatac tatgcagctt tagtgacgca cgccgtcgtc
     2161 atcttcatcg acataatcgt cgtcgtcacc ctcttcgcca ttagggtctt cgaaataggt
     2221 tccccagccg tcgtattcga catcatattt ttccgccagg ttcatcagtt gctcaacctg
     2281 agcgtcgatg agttcggcgt tcaacgcgca ctcgctgagg atgtcgcaac aaataaccgt
     2341 atcgccctct tccacttcca gctcttccgg ctccgtcact tcatagccga gtttaaaggc
     2401 ttctaccgcg gctttttcca acgtttcgaa atcgtcagcg gaaaggtgat gctcgatagt
     2461 gtacagcgca tccggatcgc tgccgtcctc aagtaactct tcaataatta accgcgtttc
     2521 ttcacgctgc tcttccagta attccgggtt tgccatagct cgttcctcat agatgtcctg
     2581 ccgatactct tattgtcaca taccgccgac gttgcctcca ccttatcgag aaaagtttta
     2641 tcaaacaggg ttgcaaatga ataatcatcc atataaagtg aattttaatt caatgagagg
     2701 cctaagccat gtgagggaag tatgtctacg ttttaccaaa aacctttttt aaagttactt
     2761 gatttcaccg ccagtgaact cactgctctg ttgcagcttg ctgccaaact gaaagccgat
     2821 aagaaaaacg gtaaagaaga acaaaagctg gtgggtaaaa atattgcgct catcttcgaa
     2881 aaagactcga cccggacacg atgctctttc gaagttgccg catacgatca gggggcgcgc
     2941 gtgacgtacc tgggttccag cgggagccag atcggtcata aggagtccat caaagatact
     3001 gcccgcgtcc tgggccggat gtttgacggt attcagtatc gaggatatgg ccaggagatc
     3061 gtcgaaacgc tggctgaata ttccggtgtg ccggtatgga acggtttaac cgatgagtat
     3121 cacccaacgc aattactggc ggatctgctc accatgcagg aacatctgcc gggtaaagcc
     3181 tttaacgaga tgacgttggt ctatgccgga gacgcacgca ataacatggg taactccatg
     3241 ctggaagccg ccgcgttaac aggattggat ctccgtctgg tcgcgccaaa agcctgctgg
     3301 ccgcaagccg cgttagtggc ggagtgcagc gccatggcga aaaagaacgg cggcgccatc
     3361 accctgaccg aagatattgc ctcgggcgta aaaggcgcgg attttatcta taccgatgtt
     3421 tgggtctcta tgggcgaacc caaagagaaa tgggcggagc gtattgccct gctgcgtgat
     3481 tatcaggtca acagccagat gatggcgtta accggcaatc cgcaggttaa gttcctgcat
     3541 tgtctgcctg cgttccatga tgacgaaacc acgctcggca aaaaaatggc cgaagagtac
     3601 ggtttacatg gcgggatgga agtgaccgac gaggtttttg agtctgcggc cagcattgcc
     3661 tttgatgaag cggaaaaccg aatgcatacc atcaaagcgg taatggtagc gacgctgtct
     3721 aaataatgtc gttatgatgc cggatggcgg ttggcctaca agatcgcaac gtgcaggcgc
     3781 cgccatccgg cacaaaatat tacgccatca gcattttcac aaccgcttta cgtacccgcg
     3841 ccggttctcc caccgcgcac aggggcttat gcacttcgcc gggataaaac accacaaagt
     3901 caccttcgtt caggacgacg gttttctcgt cgacgctcgt cggtaaaaat gcaatgtctt
     3961 tatccgccaa ccagtccgtg tgcggcgttc ccgcaggccg ggtactgaat gccatccctt
     4021 cctgaccttg tagcacaatc tgaatatcaa gataacgggc gtgatactct gcgctgcgcg
     4081 attcgcccgg ctccgtcata ttttcagaaa tcatataaaa cagcctgtcg ccgtcaatgt
     4141 catacttacc tggcgcggtc gttgccgtga catgcgcgtt gacgtgctca atcgcctgcc
     4201 gtaacgccgt cggcagccag gcctccagat gttcaatatt gccaacaatc atcgcatctc
     4261 cttagttaaa acagcgtttt atttttctct ttatacgaga aaaatggctg ccatactacc
     4321 cttactctca tcgattttgc gccagcgcat gtttatcgcc agcggtgttt atatattgtt
     4381 aatagttcgc ccaactttat gcagtaccta tgcattaacc tcagcggagc caaattgcca
     4441 tcactaacaa cgctttgata ttaaaggcgt taacataaaa acgttttagc gatcacaatt
     4501 cgctctccct gcataaatga cttctatatc catagtt
//
LOCUS       DAJVBX010000256         4498 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.256, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000256 DAJVBX010000000
VERSION     DAJVBX010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4498
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.256"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            21..2890
                     /gene="misL"
                     /locus_tag="OPV72_004153"
                     /pseudo
     CDS             21..2890
                     /gene="misL"
                     /locus_tag="OPV72_004153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462656.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="intestinal colonization autotransporter adhesin
                     MisL"
     gene            complement(2985..3449)
                     /locus_tag="OPV72_004154"
     CDS             complement(2985..3449)
                     /locus_tag="OPV72_004154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916303.1"
                     /translation="MLACLTLLFLGVGLGHLFHLYTEKNRDPEKCTAPVIVFYNNTQA
                     NLTLDFMYSLKKRTGVVSISGTYYVDNKMSGVIRRDVSYVWSENKDSTHFISTDINKV
                     TRDETLSDAVIETVLPDFYVYPGKSISYTILTQGHRGFMFTIGKRPIFFCTH"
     gene            complement(3460..4316)
                     /locus_tag="OPV72_004155"
                     /pseudo
     CDS             complement(3460..4316)
                     /locus_tag="OPV72_004155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462658.4"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            complement(4369..4482)
                     /locus_tag="OPV72_004156"
     CDS             complement(4369..4482)
                     /locus_tag="OPV72_004156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_453069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916304.1"
                     /translation="MIFSPQYKTGGLTNKKTKRTFTPESAIMRKAVSTLTC"
BASE COUNT         1176 a         1119 c         1141 g         1062 t
ORIGIN      
        1 gccataatgc aggaggcaga atgccaactc cccaaaatta ctcattcatc gccatagcgg
       61 tatcagcagc attagcctct atggtatttc cctcccaggc ggcctgggtt gacgttgata
      121 gtctgccatc cagtgggctg gtcagccagc tgccgccgga attacaggct attattcccg
      181 ctcaggccag taccggtttc accaaagtcg gtaccatgcc caactacgtt tatcagtgga
      241 acaccggcac catcccggtt tatggcaatg gcctcacgct taatgggccg ggtgcggagg
      301 cgtttgaaca cactgtcacg gttattcaga acagcgggac gggaagtccg ggcgtgattt
      361 ttggcaacga cctgaccatt cggacgcagt cggcgaatgc cgcgaataat ggtagagacg
      421 tcgatggcat ccgtactcac ggcgcaaata ctccggataa cccggtattt attattaccg
      481 gtgaccgtac caacatctac gtggatggtc aggatggtga cggtattaac gccggatata
      541 actcactggg ccagggttgg accggatcgg ccaatattta cgtcggcgac gatctgtata
      601 tcaaaacgac cggtagccag ggacgtggaa ttacagctaa cgccatgcgg gatgcgtcac
      661 gtgccaaaaa tacgattgtc gtcggcaatc gtgtgcacat atagttacta ccggcgacag
      721 ttcggagggg ctgcgtaccg gacaaagcgg ttcgttgatt cgtctgggtg acgatgcaac
      781 catcgaaacc tccggcgcat cctcaacggg gatttacgca gcatcctcct ccagaaccga
      841 gcttagcaac aacactacta ttacggtgaa cggtgccagc gcacacgcgg tatatgcaac
      901 taacgctacc gttaatttgg gagagaatgc cactattagc gttaacagcg ccagtaaggc
      961 tgcatcctat agtaaagccc ctgccggttt atacgccctc tcccgaggcg ccattaatct
     1021 ggcaggcggt gcggctatta ctatggcggg cgataacagt agcgaaagtt acgccatcag
     1081 cacggaaact ggcggcattg ttgacggttc ttcaggaggt cgtttcgtca tcgacggtga
     1141 tattcgtgct gctggcgcca ccgctgccag cggtacgcta ccgcagcaga acagtacgat
     1201 taagctcaat atgacggaca actcgcgatg ggacggggcg tcgtacatca ccagcgctac
     1261 ggcgggcaca ggcgttatct ctgtacaaat gagcgatgcg acctggaata tgaccagcag
     1321 ctcaacgctc actgacctga cgctgaatag tggcgcaatc attaacttca gccatgaaga
     1381 tggcgaacca tggcaaacgc tcaccatcaa tgaagattat gtaggcaacg gcggtaagct
     1441 ggtctttaat actgtgctca acgatgatga ttccgaaacg gacaggctgc aggttctcgg
     1501 caatacttca ggcaacacat ttgttgcagt aaataatatt ggaggagccg gggctcaaac
     1561 cgttgaaggt attgaaattg ttaacgttgc tggcaattcc aacggtactt tcgaaaaagc
     1621 aagtcgtatt gttgccggag cctatgacta caacgtggtg cagaaaggta aaaactggta
     1681 tctgaccagc tacattgagc cggacgaacc gattattcct gatccggtag accctgttat
     1741 tcctgaccct gtcattcccg atccggtaga ccctgatcca gtagacccgg ttatccctga
     1801 ccctgttatt cccgatccgg tggaccctga tccagtagac cctgatccag tagacccggt
     1861 catccctgat ccggtcattc ctgacatagg acaatctgac acaccgccga taacagaaca
     1921 tcagttccgt ccggaagtgg gcagctatct tgccaacaac tatgcggcaa atacgctgtt
     1981 catgacgcgt ctccatgacc gtctgggtga aacccagtac accgacatgc tgacgggtga
     2041 gaagaaggtc accagcctgt ggatgcgtaa cgtcggcgcc catactcgct tcaacgatgg
     2101 cagcgggcag ctaaaaaccc gcatcaacag ctatgtgtta caactgggag gcgatctggc
     2161 acagtggagc actgacagtc ttgaccgttg gcatattggt gcaatggcag gttatgccaa
     2221 cagccagaac cgcacgcagt cgtccgtgag tgactatcat tcccgtggtc aagtcaccgg
     2281 ttacagcgtc ggcctttacg gcacctggta tgctaacaat atcgatcggt ctggggctta
     2341 tgtggatacc tggatgctgt acaactggtt tgataacaag gtcatgggtc aggatcaggc
     2401 cgctgagaaa tataaatcca aaggaattac cgcctcggtt gaagccggtt acagtttcag
     2461 gttaggtgaa agcgcgcatc aaagctactg gttgcagccc aaagcgcagg tggtatggat
     2521 gggcgtgcag gctaacgacc atcgcgaagc caatggtacc ctcgtcaagg atgataccgc
     2581 cggtaatctg ctaacccgca tgggcgtaaa agcctatatt aacggccaca atgctattga
     2641 tgacaataaa tctcgagagt tccagccatt cgtggaagcg aactggatcc ataatacgca
     2701 gcctgccagc gtgaagatgg acgatgtcag cagcgatatg cgtggtacga aaaatattgg
     2761 tgaactgaaa gtgggtattg aaggacaaat taccccgcgc ctgaacgtat ggggtaacgt
     2821 ggcgcaacag gtaggtgacc agggctatag taatacccaa ggcctactgg gggttaaata
     2881 cagtttctga ttcaggtaac aacagagccg ctgatcttca gcggctttta cccggaagcg
     2941 ctttcatttg gctgatacgt tccatgaacg gctcccaaaa ccgcttaatg tgtacagaaa
     3001 aatatcgggc gtttcccgat ggtgaacata aagccacgat gaccctgagt caggatggtg
     3061 taactgatac ttttccctgg atagacataa aaatcgggta aaaccgtctc gataaccgca
     3121 tcggacagtg tttcgtcacg cgtgactttg ttgatatccg tcgatataaa atgggtgctg
     3181 tctttatttt cactccatac ataggaaaca tcacggcgga tcacgccgct cattttatta
     3241 tcgacgtaat acgttccgct gatggaaacc actccagtgc gttttttcag cgaatacata
     3301 aagtccagcg tcaggttagc ctgagtgttg ttataaaaca caatcacagg cgccgtacat
     3361 ttctctggat cccggttctt ttccgtatat aaatgaaaaa gatgcccaag ccctacaccc
     3421 agaaacagta gcgtcaggca ggctaacatc agtgcctttt tacccatgtg tcaccccgcg
     3481 gaaaaaaagc gtcacgcagc ctgtatcacc gcgcgtttta taaggttgct gacaaatcaa
     3541 tgccgtaacc gctggggtgc gactgctgga agggaaatag acccatgggt atttctgaca
     3601 atccataccg gtttttagaa tcattaactt atagcctgca aagcggctac cgctttcgat
     3661 atcttcattc cgcgagaaaa aatgacagcc ctgagttgtt tcaaccagcg tgtagcgatc
     3721 ataaaaatcc ttatcaggaa cggtttgcca gctgatagtg ccaagcaaaa taccgacagc
     3781 aaatgtcccg gtcatccaaa gtacaggtac ataatgttta aaccaacgcc ctgacatacg
     3841 cggtggcgcc tcaccctttt ttctattgtc tgagcgaagt ctttgcggat ggtcatgagg
     3901 ctcacaccag gctcaatctg aaagcctcta cgcggaaccg tgattatcag cgtatcttca
     3961 ttttcgccaa cggtacgtaa tccgcggcga ataatggaga tattctgata aagcgtattt
     4021 gccgacacca ccatgccgtc ttcttcctat actttttgaa agaatgtttg ttgtgagacg
     4081 acggaggggg cgttttccag cagaaggcgc aagcagcggc tggcgggcgt tgtcagaata
     4141 atgttgagat ctggcctcga taatgacgcc aggcgattca tttctggatt aaattcaata
     4201 ttatcgttaa ttatccataa catcgcattg ttaccatgcc aaaacataac gtagttggag
     4261 agggttaata gacaccactg agtatagtct gatgctgtgg ctgcgtagca ggacatggat
     4321 tgtcccctgc acataccgat catatagaag agcgagaggc ataagacatt aacaggtaag
     4381 cgtagacacc gcttttctca ttatagcaga ctcaggggtg aaagtacgtt tggttttctt
     4441 gttcgttaag cctcctgttt tgtattgagg tgagaatatc acctttaatc aagtagcc
//
LOCUS       DAJVBX010000257         4357 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.257, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000257 DAJVBX010000000
VERSION     DAJVBX010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4357
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.257"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            27..1118
                     /locus_tag="OPV72_004157"
     CDS             27..1118
                     /locus_tag="OPV72_004157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HCR9916305.1"
                     /translation="MMKKSKAMLFIAPALFSYAMAAQACTTLAIQDKQGDIFHGRTLE
                     YMQDLPSWLTYYPAGTQFDKKTPDGSQGISYQAKYPILAITSTITDGDSRDILEGMNS
                     AGLSFSENMIMNAQLPPLPASEYKQAIPVTSLGEWALARFATVGEVKQAIKEGKFWSP
                     ELHRFGDLKSPFHYAFYDKKGGSIVVEVENGKFHVYDNPTRVMTNGPAFPWHLTNLNN
                     YTQLTNVDRSSGTLGGIKVMQPDSGIAIADLPSSDTSVSRFIRGVYYTTYAPQATSAH
                     DAMNTLAHIMSRFDRPKNITVDYMGSEGEGNATRKPVSEYTVWTTLSDLTHGEMMVRG
                     YNDINYKTWSLSQFKNATAPVFEKINVKG"
     gene            1164..1955
                     /locus_tag="OPV72_004158"
     CDS             1164..1955
                     /locus_tag="OPV72_004158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HCR9916306.1"
                     /translation="METTGGCFSLSCTVINYHDHQRQDGMLNPFKIPWIWIGGRMVIP
                     EVRQERLYQKIANLIIKLINDNIFPPGTFLPPERELAKQLGVSRASLREALIVLEISG
                     WIVIQSGNGVIVSDKKHLASDYTIEEILSTRELVDSHCARLAAQNDNVDVINQIEAIY
                     HRMDQAINDNNVHGFYSLDKEFHLAISEASRNRVLFDMSRMLWEQRINIPYAGLDEQS
                     GDRNVLLNLNKQHKAIVDAMRQSDADSAYEGSLEHLRYVRKIVGG"
     gene            complement(2014..3039)
                     /locus_tag="OPV72_004159"
     CDS             complement(2014..3039)
                     /locus_tag="OPV72_004159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HCR9916307.1"
                     /translation="MKVKAVFINKPGEVETRWVDYPHKKENEVLIKVDAAGICGSDIG
                     AFRGTNPLVTYPRIIGHEVTGIVLQEGTGMPDNIKKGDRVIVDPYIYCGHCYPCSVGR
                     TNCCENLNVIGVHIDGAMQEVVTHPAHLIHKIPDNVPSEMAPLAEPLTIALHALHRAN
                     VKAGEYVAIIGAGAIGLMAALSARHYKATPILIDIVEERLRYAQKLGVPYVLNAADDQ
                     VIDAIKNITHGTMAQVVIEASGANSAIRNTLDLASFAGRISFTGWPKQETSLPTNLIT
                     YKELDLRGSRTSAGEFDEALRMLSTLEINPQDVVSKVVNLDEIPDAVKELDRYPERYL
                     KINAVFH"
     gene            complement(3014..4300)
                     /locus_tag="OPV72_004160"
     CDS             complement(3014..4300)
                     /locus_tag="OPV72_004160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR9916308.1"
                     /translation="MKRKTMGWLIVFLLFIVYMLNYMDRSALSITAPLIEKELGFNAA
                     EMGMIFSAFFIGYALFNFIDGWASDKVGPKTVFLIAALLWSVFCGLTGLVTGLWTMLI
                     VRVLFGMAEGPVSAAGNKIINNWISRKESATAIGIFSAGSPLGGAVSGPIVGLLALSL
                     GWRPAFGIIFLFGLVWVLLWYFIVSDKPTMSKRLAPEERIDFENHEDVILSDDGRATP
                     SLGYYMKQPMVWATTLAFFSYNYILFFFLTWFPSYLNHSLHLDIKEISIATVIPWVIG
                     AIGMVLGGVCSDVIYRITGNALLSRRLILGVCLAGAAVCVAVSGTVSTIGSAITLMSV
                     SLFLLYLTGPIYWAVIQDVVHKDKVGSVGGAMHGLANISGIIGPLVTGFIVQFSGKYD
                     YAFYLAGAIAIVSSLLVFVFVKSKGFKANESQSCVH"
BASE COUNT         1236 a         1044 c         1006 g         1071 t
ORIGIN      
        1 caatccattt tacaaacaag gagagcatga tgaaaaaaag taaagcaatg ttatttatcg
       61 ctccggcgct gttttcatac gccatggctg cacaggcctg cacaaccctt gctattcagg
      121 ataaacaagg cgatattttt catgggcgta cgctggaata tatgcaggat ttaccctcat
      181 ggttaacgta ttatccggcg ggaacgcagt ttgataaaaa aacgccggat ggcagccagg
      241 ggataagcta tcaggcgaag tatccgatac tggccattac ttccaccatt actgatggcg
      301 atagcagaga catacttgaa ggcatgaata gcgcgggatt gtcatttagt gaaaacatga
      361 tcatgaatgc gcagttgccg ccattgcccg cgagtgaata taaacaggca attcctgtca
      421 cctcgttggg agaatgggcg ctggcccgtt ttgctactgt cggcgaggta aaacaggcaa
      481 taaaagaggg caaattctgg tcaccggaac tgcatcggtt tggcgatctg aaatcgccat
      541 ttcattacgc gttttacgac aagaaaggag gaagcattgt cgttgaagtg gaaaatggca
      601 aattccatgt ctatgacaat cccactcgcg tgatgacaaa tggtcccgca ttcccctggc
      661 atctgacaaa tctgaataat tatacgcaat taaccaatgt ggaccgctct tcaggcacat
      721 tgggcgggat aaaagtgatg cagcctgata gcgggattgc tattgcagac ttgccatcgt
      781 ccgatacgtc ggtttcccgt tttatacgcg gcgtttatta cactacatat gcgccgcaag
      841 cgacatccgc ccacgacgca atgaatacgc ttgcacatat tatgagccgt tttgatcgtc
      901 cgaaaaatat tacggttgat tatatgggga gtgaagggga aggcaacgcc acccgcaaac
      961 cggtctcaga atatacggtc tggacaacgc tgtctgactt gacgcacggt gagatgatgg
     1021 tgcgcggcta caatgatatc aactataaaa cctggtccct ttctcagttt aagaacgcga
     1081 ctgcgcccgt gttcgagaaa atcaacgtca aaggataaac cgctcgtctc tgtttagttt
     1141 ccccggtagt ctcggcgaag gtaatggaga ctaccggcgg ttgcttctct ttatcatgca
     1201 cggtaattaa ttatcacgat caccagcgcc aggatggtat gctaaatcca ttcaaaatcc
     1261 cctggatatg gattggaggg cgcatggtta tacctgaggt caggcaggag aggctctatc
     1321 agaagatagc caacctcatc attaagctga tcaatgataa tatttttcca ccgggaactt
     1381 ttttaccgcc agaacgcgaa ctggcaaaac agcttggcgt gagccgcgcc tccttgcgag
     1441 aagcccttat tgtactggag atctccggat ggatcgtgat tcagtccggt aatggggtta
     1501 tcgtttcaga taaaaaacac cttgccagtg actataccat cgaagaaatt ctctctactc
     1561 gcgagctggt cgatagccat tgtgcgcgct tagccgcaca aaacgataac gttgacgtca
     1621 tcaaccaaat agaggcgatt tatcatcgta tggatcaagc cattaacgat aataacgtcc
     1681 acggctttta ctcgctggat aaagagtttc accttgcgat ctctgaggcc agccgtaacc
     1741 gggtgttgtt tgatatgtcc cgtatgttat gggaacaacg gattaatatc ccttacgccg
     1801 ggcttgatga acagtctgga gacagaaatg ttttacttaa tctcaacaaa caacataaag
     1861 cgatagtgga tgcgatgcgc cagtctgatg ctgacagcgc ttatgaggga tcgctggaac
     1921 atttacgcta tgtgagaaag attgtcggcg gctaagtttg tcggtaaata acaccgcatg
     1981 gcggatatgc catgcggtag aactcgccgt aaatcaatgg aaaacagcat taatctttaa
     2041 gtaacgctcc ggatagcgat caagttcttt aactgcatca gggatctcat caagattgac
     2101 gaccttactg acaacatctt gcggattaat ctccagcgtt gacagcatgc gtaatgcctc
     2161 atcaaattca ccggcactgg tgcgggagcc gcgtaaatcc agttctttgt aggtgatcag
     2221 gttcgtcggc agcgacgttt cctgttttgg ccatccggta aacgaaatac gaccagcaaa
     2281 cgatgctaaa tcaagcgtat ttcgaatagc gctatttgcg ccggaggctt ctatcacgac
     2341 ctgcgccatg gtgccgtggg tgatattttt aatagcgtcg ataacctgat cgtcagcggc
     2401 gttcagtaca taaggaacgc caagcttttg cgcatagcgt agcctttctt ccacaatatc
     2461 gatcagaata ggcgttgcct tgtaatgacg cgcgcttaat gccgccataa gaccaatggc
     2521 ccccgcgccg atgatggcaa catattcccc ggccttaacg tttgcccgat gcagcgcgtg
     2581 tagagcgatg gtcagcggtt ctgccagcgg cgccatttca gaaggcacat tatctggtat
     2641 tttatgaatt aaatgtgcgg gatgagtaac cacctcctgc attgcgccat cgatatgcac
     2701 gccaatgaca tttaaatttt cacaacaatt agttctgccg acagagcaag ggtagcagtg
     2761 accacaataa atataggggt caacaatcac gcggtcgcct tttttaatat tgtccggcat
     2821 tccggtgcct tcctgaagaa caattccggt cacttcatgc ccaataattc ttgggtaagt
     2881 aacaagtggg ttcgttccac gaaaagcccc gatatccgat ccgcaaatgc ctgcggcatc
     2941 aaccttaatt aatacttcat tttctttctt atggggataa tccacccagc gggtttcaac
     3001 ttcaccaggc ttattaatga acacagcttt gactttcatt ggctttgaat cctttacttt
     3061 ttacaaacac gaagaccaac aggcttgaaa cgatagcgat agcaccagcc agatagaacg
     3121 catagtcata tttaccgcta aattgaacga taaaaccggt gacaagcgga ccgataatac
     3181 cggatatatt agccaggcca tgcatggctc cgccgacgct ccctacctta tctttatgaa
     3241 caacatcctg aataaccgcc caataaattg ggcctgttaa atagagcagg aagagtgaaa
     3301 ctgacatgag cgtaattgcg ctaccaatag tgctaacggt accggaaacg gcaacacata
     3361 ccgccgcgcc tgccagacat acgcccagaa taagtcgacg tgagagcagg gcattaccgg
     3421 taatccgata aattacatca gaacagacgc cgccgagcac cataccaatg gcgccgatga
     3481 cccagggaat taccgtggcg atactaattt ctttaatatc gagatgtaac gaatggttca
     3541 gataacttgg gaaccaggtc aggaagaaaa aaagaatata gttgtagctg aaaaaagcca
     3601 gagttgtcgc ccataccatt ggttgtttca tgtaatagcc gagtgaaggc gtagcccggc
     3661 catcatcaga taaaataacg tcctcatgat tttcaaaatc aatgcgttct tccggcgcca
     3721 ggcgtttact cattgttggc ttatcgctaa cgataaagta ccacagtagt acccagacca
     3781 agccaaataa gaaaataatg ccaaatgcgg ggcgccagcc taaggataac gccaacaggc
     3841 ccacaatcgg cccggacacc gcgccgccga gcggggaacc ggcgctaaaa attccgatcg
     3901 ccgtggcaga ctcctttcgg gaaatccagt tattgatgat tttatttccg gcagcgctga
     3961 ccggtccttc agccataccg aaaagaacgc gcacgataag cattgtccac aatccggtga
     4021 ctaaaccagt taagccacaa aatacagacc atagtaacgc tgcgatgaga aaaaccgttt
     4081 ttggcccaac tttatcgctg gcccagccat caataaaatt aaacagggcg tatccgataa
     4141 aaaatgcgct gaagatcatt cccatctccg cggcgttaaa tcctaactcc ttttcgatca
     4201 agggggcagt tatcgacaat gctgaacgat ccatatagtt gagcatgtaa actataaata
     4261 gaagaaaaac gataagccat cccattgttt ttcttttcat gattaatcct cttattgtgg
     4321 tctagcggcc tgaccacaat attttaaggt tattttc
//
LOCUS       DAJVBX010000258         4338 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.258, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000258 DAJVBX010000000
VERSION     DAJVBX010000258.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4338
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.258"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(5..478)
                     /locus_tag="OPV72_004161"
     CDS             complement(5..478)
                     /locus_tag="OPV72_004161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001514095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber protein"
                     /protein_id="HCR9916309.1"
                     /translation="MGEGSALPVGVPVPWPSATPPAGWLKCNGAAFSSEMYPNLAKAY
                     PANKLPDLRGEFIRGWDDERGIDPGRQLLEWQKGTLVGGRDDNDAAVDISYMSNGNSI
                     DYGGDKTFSTNYRSDYLWYAILGNVTGRAKAALSGSFFNVTRPRNIAFNYIVRAT"
     gene            550..1122
                     /locus_tag="OPV72_004162"
     CDS             550..1122
                     /locus_tag="OPV72_004162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016234457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCR9916310.1"
                     /translation="MQIGYIRVSTNDQNTDLQRNALNCAGCELIFEDKISGTKSARPG
                     LKKLLRTLSEGDTLVVWKLDRLGRSMKHLITLIEELREKGVNFRSLTDSIDTSTPMGR
                     FFFHVMGALAEMERELIVERTLAGLEAARAQGRIGGRRPKLTKEQHEQIARLIKNGYS
                     RKQLAIIYDIGISTIYRYHPVEELQTQAEL"
     gene            1403..2785
                     /locus_tag="OPV72_004163"
     CDS             1403..2785
                     /locus_tag="OPV72_004163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCR9916311.1"
                     /translation="MEKKLGLSALTALVLSSMLGAGVFSLPQNMAAVASPAALLIGWA
                     ITGVGILLLAFAMLILTRIRSELDGGIFTYAREGFGELIGFCSAWGYWLCAVIANVSY
                     LVIVFSALSFFTDTPALRLFGDGNTWQAIVGASVLLWIVHFLILRGVQTAASINLVAT
                     LAKLLPLGAFIVLAIMMFKLDTFTLDFTGVELGIPVWEQVKNTMLITLWVFIGVEGAV
                     VVSARAKNKRDVGRATLLAVLAALGIYLLVTLLSLGVLARPELAEMRNPSMAGLMVKM
                     MGPWGEIIIAAGLIVSVCGAYLSWTIMAAEVPFLAAAYKSFPGIFARQNAQGAPSASL
                     WLTNICVQICLVLIWLTGSDYNTLLTIASEMILVPYFLVGAFLLKIATRPLHRAVGIG
                     ACIYGLWLLYASGPMHLLLSVVLYAPGLLVFLYARRTHKHDNVLNRQEVVLIGLLLVA
                     AVPATWMLVG"
     gene            complement(2847..3182)
                     /locus_tag="OPV72_004164"
     CDS             complement(2847..3182)
                     /locus_tag="OPV72_004164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlpM family protein"
                     /protein_id="HCR9916312.1"
                     /translation="MGLVIKAALGALVVVLIGLLSKTKNYYIAGLIPLFPTFALIAHY
                     IVASERGIDAMRTTIVFSMWSIIPYFIYLATLWYFSGVMRLPVALGGAVVCWGLSAWL
                     LIFCWIKWH"
     gene            3309..4040
                     /gene="rstA"
                     /locus_tag="OPV72_004165"
     CDS             3309..4040
                     /gene="rstA"
                     /locus_tag="OPV72_004165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RstA"
                     /protein_id="HCR9916313.1"
                     /translation="MNRIVFVEDDAEVGSLIAAYLAKHDIDVIVEPRGDRAEDLILIT
                     QPDLVLLDIMLPGKDGMTICRDLRHRWQGPIVLLTSLDSDMNHILALEMGACDYILKT
                     TPPAVLLARLRLHLRQSEQTQQAKSLQESALTPHKALRFGALTIDPLNRAVQLNGDFI
                     SLSTADFELLWELATHAGQIMDRDALLKTLRGVNYDGLDRSVDVAISRLRKKLLDSAA
                     EPYRIKTIRNKGYLFAPHAWDETTG"
     gene            complement(4105..>4338)
                     /locus_tag="OPV72_004166"
     CDS             complement(4105..>4338)
                     /locus_tag="OPV72_004166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916314.1"
                     /translation="YIFMVVICLISQFAKKDGNIAAGRHSVINFVNWLRVFFNLIFLS
                     EKDVIMNRNAEKTVIKGLFRLIKIALMYTVSVF"
BASE COUNT         1059 a         1081 c         1055 g         1143 t
ORIGIN      
        1 gtttctatgt tgctctcaca atgtagttaa aggcgatgtt gcgtggacga gttacattaa
       61 aaaaggaccc acttaaagca gctttggcac gaccagtgac gttacccaga attgcatacc
      121 ataaataatc actccggtaa ttcgttgaaa atgttttatc gccaccgtaa tcaatactat
      181 ttccgttact catatatgaa atatcaactg cggcatcatt gtcatctcta ccaccaacca
      241 aagtaccttt ctgccactca agcaactggc gaccaggatc aatcccgcgc tcgtcatccc
      301 agccacgaat aaactcaccc cgtaaatccg gtaatttatt cgcggggtaa gcctttgcca
      361 gattggggta catttcagaa gaaaatgctg ctccgttaca tttcagccac cctgctggcg
      421 gtgtggctga gggccacgga acaggcacac caacgggcag tgcagagcct tcccccaaac
      481 caacgttttc gtcttaactc ccacctatac cagctatgta tttttaacaa aacaaagagg
      541 atatttttca tgcaaattgg ctacattcgt gtgtcaacaa atgaccagaa tacagattta
      601 caacgaaacg cactgaactg cgcaggatgt gaactgattt ttgaggataa aatcagcgga
      661 acaaagtcag cccgaccggg attgaaaaag ctgctcagaa cgttatcaga aggagatacg
      721 ctcgttgtct ggaagctgga caggctgggc agaagcatga aacacctcat cactcttatt
      781 gaggaactgc gggaaaaagg ggttaacttc cgtagtctta cagacagcat tgatacgtca
      841 acacccatgg gacgtttctt ttttcacgtc atgggggctt tagcggaaat ggagcgtgaa
      901 ttaatagttg aacgaacact ggccggactt gaagcagcac gtgcacaggg gcgtattggt
      961 ggacgtcgtc cgaaactgac aaaagagcaa catgaacaaa tagcaaggct gatcaaaaat
     1021 ggctatagca ggaaacagtt ggcaattatt tacgatatcg gtatatcgac gatttatcgt
     1081 tatcaccctg tagaggaact tcaaactcaa gctgagttgt aattcttttt ctgatattga
     1141 aatgccgcgg cgatgtaatt tatctcacgg aaataggtac gtttatcgcg cggcgcatca
     1201 atcaggcttt ctcgcgggat gccagttccg tcaaatatcg cgatgaatct cacttttcgc
     1261 ttttttggcg ataaatctta tccaggccgt tgcatgcggt cccttctctc cgtaaaatcc
     1321 cgcgccttag tggctttcac catttttatg cgttttgcca taataattat tcttccaatt
     1381 tcatttttat agctggatac caatggaaaa aaaactggga ctgagcgcgc tgaccgcgct
     1441 ggttttaagc tcaatgcttg gcgcaggtgt tttcagtctg ccccagaata tggccgccgt
     1501 tgccagtccg gctgcgttgt taattggctg ggccattacc ggcgtgggga tactcctact
     1561 ggcattcgcc atgttaatcc ttacgcgcat tcgctccgag cttgacggcg gcatctttac
     1621 ttacgcccgc gaaggcttcg gcgaactgat tggcttttgt tctgcctggg gctattggct
     1681 gtgcgcggtc atcgccaacg tatcctattt ggttatcgtc ttttcagcgc tgagtttctt
     1741 taccgatacg cctgccctgc gtctgtttgg cgacggtaat acctggcagg ctattgtcgg
     1801 cgcttcagtc ctgctctgga ttgtccattt cctcatcctg cgcggcgtac aaacggcagc
     1861 cagcatcaat ctggtcgcga ctctggcgaa actgttaccg ctcggcgcgt ttattgtgct
     1921 ggctatcatg atgttcaaac tggatacctt cacactggac ttcaccggtg ttgagctcgg
     1981 tattcccgta tgggaacagg tcaagaacac catgcttatt acgctgtggg tgtttattgg
     2041 cgttgaaggc gccgtcgtcg tctcggcccg agcgaaaaat aaacgcgatg taggccgcgc
     2101 cacgctactg gcggtactcg cagcgctggg aatatatctc ctggtcacgc tgctttctct
     2161 tggcgttctt gcgcgtccgg aactggcgga gatgcgcaac ccgtcgatgg ccggtctgat
     2221 ggtgaaaatg atggggccgt ggggagaaat tattattgca gcgggactga ttgtgtctgt
     2281 ctgcggggct tatctaagct ggactatcat ggcggcagag gtgccgtttc tggcggcagc
     2341 ctataaatcc ttcccgggca tcttcgcgcg acaaaatgcg caaggcgcgc cttctgcgtc
     2401 gttatggctc accaacatct gtgtgcaaat ctgtctggtg ctgatctggc tgaccggttc
     2461 ggactacaac acactattga cgattgcgtc agaaatgatt ctggtgccct actttctggt
     2521 cggcgcattt ctgctgaaga ttgcaacgcg tcccctccat cgggcggtcg gtatcggagc
     2581 ctgtatttat ggcttatggt tattatatgc gtcgggccct atgcacctgc tgctgtccgt
     2641 cgtactgtac gcgcctggat tactggtttt cctgtatgcg cgtcggacgc acaagcatga
     2701 caatgtatta aatcgtcagg aagtcgtgct gattggttta ttgctggtcg cggcggttcc
     2761 ggctacgtgg atgctggtgg gttaacaacc tccctatcgt aatatccgtc tgtattacga
     2821 tggggaaacc acggtctttg ccaatattaa tgccatttaa tccagcaaaa aatcagcagc
     2881 cacgcgctta gcccccagca gaccaccgca ccgccaagcg cgacgggcag gcgcatcacg
     2941 ccgctgaaat accatagcgt tgcaagataa atgaaataag gaatgatcga ccacatgcta
     3001 aagacgatgg tggtacgcat cgcgtcgatg ccccgctcgc tagccacgat atagtgcgcg
     3061 ataagcgcaa acgttggaaa cagaggaatt aatccggcga tataataatt ttttgttttt
     3121 gacagcagac caatcaatac gacgaccagc gcccccaggg cagctttaat cacgagtccc
     3181 attaccttgc cttaacatgc taataacaac agcatgtagc ataacggaac cgctctcgtt
     3241 tagaaaagat ttatggaagg gaaaacagag gaggtgtatg ttggcgtttt ctattctcca
     3301 tttataatat gaaccgcatt gtatttgttg aagacgacgc tgaagtgggt tctctcattg
     3361 ccgcttatct ggcgaaacat gatattgatg tcattgttga gccgcgtggt gaccgggcgg
     3421 aggatcttat cctcatcact cagcccgatc tggttttact ggatattatg cttccaggta
     3481 aagatggcat gacgatatgc cgcgatttac gccaccgctg gcaaggtccg attgtcctgc
     3541 tcacctcgct ggacagtgat atgaatcata ttctggcgct ggagatgggc gcctgcgact
     3601 acatcctcaa aaccacgcct ccggccgttt tgctggcgcg tctgcgctta cacctgcggc
     3661 aaagcgaaca aacgcaacag gcaaaaagtc ttcaggagag cgcgcttacg ccgcataaag
     3721 cgctgcgttt tggcgcgtta accatcgatc cccttaaccg ggcggtccag ctcaatggcg
     3781 atttcatatc gctctccacc gccgattttg aattgctctg ggaactggcg acacacgccg
     3841 gacaaattat ggatcgcgac gcgttgctaa aaacgctgcg cggcgttaat tatgatggtc
     3901 tggatcgcag cgtggatgtg gcgatttccc gcctgcgtaa gaaactgctg gatagcgctg
     3961 ctgagcccta tcgtataaag accattcgca ataaaggcta tctttttgcc cctcatgcct
     4021 gggacgaaac gacgggataa gtgagtcgac agattttacc tgcctttatc aagtcatagt
     4081 ggcgatgctc atcaccgcca ctgttcaaaa aacagacacc gtatacatca gtgctatttt
     4141 tattagtcgg aacagcccct ttattaccgt tttctctgcg ttgcggttca tgattacgtc
     4201 tttttcgctc aagaaaatta aattaaaaaa aactcgaagc cagttcacaa aattgataac
     4261 agaatgtctg cccgccgcta tattgccatc ttttttcgca aattgtgaaa tcaaacaaat
     4321 cacaaccatg aatatata
//
LOCUS       DAJVBX010000259         4327 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.259, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000259 DAJVBX010000000
VERSION     DAJVBX010000259.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4327
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.259"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..979
                     /gene="rfbB"
                     /locus_tag="OPV72_004167"
     CDS             <1..979
                     /gene="rfbB"
                     /locus_tag="OPV72_004167"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HCR9916315.1"
                     /translation="AGNLESLSDISESNRYNFEHADICDSAEITRIFEQYQPDAVMHL
                     AAESHVDRSITGPAAFIETNIVGTYVLLEVARKYWSALGEDKKNNFRFHHISTDEVYG
                     DLPHPDEVENSVTLPLFTETTAYAPSSPYSASKASSDHLVRAWRRTYGLPTIVTNCSN
                     NYGPYHFPEKLIPLVILNALEGKPLPIYGKGDQIRDWLYVEDHARALHMVVTEGKAGE
                     TYNIGGHNEKKNLDVVFTICDLLDEIVPKATSYREQITYVADRPGHDRRYAIDAGKIS
                     RELGWKPLETFESGIRKTVEWYLANTQWVNNVKSGAYQSWIEQNYEGRQ"
     gene            979..1878
                     /gene="rfbD"
                     /locus_tag="OPV72_004168"
     CDS             979..1878
                     /gene="rfbD"
                     /locus_tag="OPV72_004168"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HCR9916316.1"
                     /translation="MNILLFGKTGQVGWELQRSLAPVGNLIALDVHSKEFCGDFSNPK
                     GVAETVRKLRPDVIVNAAAHTAVDKAESEPELAQLLNATSVEAIAKAANEIGAWVVHY
                     STDYVFPGTGDIPWQETDATSPLNVYGKTKLAGEKALQDNCPKYLIFRTSWVYAGKGN
                     NFAKTMLRLAKERQTLSVINDQYGAPTGAELLADCTAHAIRVTLNKPEVAGLYHLVAG
                     GTTTWHDYAALVFDEARKAGITLALTELNAVPTSAYPTPASRPGNSRLNTEKFQRNFG
                     LILPQWELGVKRMLTEMFTTTTI"
     gene            1926..2804
                     /gene="rfbA"
                     /locus_tag="OPV72_004169"
     CDS             1926..2804
                     /gene="rfbA"
                     /locus_tag="OPV72_004169"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HCR9916317.1"
                     /translation="MKTRKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTL
                     MLAGIRDILIISTPQDTPRFQQLLGDGSQWGLNLQYKVQPSPDGLAQAFIIGEEFIGN
                     NDCALVLGDNIFYGHDLPKLMEAAVNKESGATVFAYHVNDPERYGVVEFDQNGTAVSL
                     EEKPLQPKSNYAVTGLYFYDNSVVEMAKNLKPSSRGELEITDINRIYMDQGRLSVAMM
                     GRGYAWLDTGTHQSLIEASNFIATIEERQGLKVSCPEEIAFRKNFINAQQVIKLAGPL
                     SKNDYGKYLLKMVKGL"
     gene            2805..3356
                     /gene="rfbC"
                     /locus_tag="OPV72_004170"
     CDS             2805..3356
                     /gene="rfbC"
                     /locus_tag="OPV72_004170"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HCR9916318.1"
                     /translation="MMIVIKTAIPDVLILEPKVFGDERGFFFESYNQQTFEESIGRKV
                     TFVQDNHSKSKKNVLRGLHFQRGENAQGKLVRCAVGEVFDVAVDIRKESPTFGQWVGV
                     NLSAENKRQLWIPEGFAHGFVTLSDYAEFLYKATNYYSPSSEGSILWNDETIGIEWPF
                     SQLPELSAKDAAAPLLHQALLTE"
     gene            3362..>4327
                     /locus_tag="OPV72_004171"
     CDS             3362..>4327
                     /locus_tag="OPV72_004171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-6-deoxy-delta-3,4-glucoseen reductase"
                     /protein_id="HCR9916319.1"
                     /translation="MSHIIKIFPSNIEFSGREDESILDAALSAGIHLEHSCKAGDCGI
                     CESDLLAGEVVDSKGNIFGQGDKILTCCCKPKTALELNAHFFPELAGQTKKIVPCKVN
                     SAVLVSGDVMTLKLRTPPTAKIGFFPGQYINLHYKGVTRSYSIANSDESNGIELHVRN
                     VPNGQMSSLIFGELQENTLMRIEGPCGTFFIRESDRPIIFLAGGTGFAPVKSMVEHLI
                     QGKCRREIYIYWGMQDSKDFYSALPQQWSEQHDNVHYIPVVSGDDAEWGGRKGFVHHA
                     VMDDFDSLEFFDIYACGSPVMIDASKKDFMMKNLSVEHFYSDAFTA"
BASE COUNT         1210 a          856 c         1061 g         1200 t
ORIGIN      
        1 cgccggtaat cttgaatccc tttctgatat ttctgaaagt aatcgctaca attttgaaca
       61 cgcggatatt tgtgattccg ctgaaataac gcgtattttt gagcagtacc agccggacgc
      121 ggtgatgcat ttggctgcgg aaagtcatgt ggaccgttcg attaccgggc cggcagcatt
      181 tattgaaacc aatatcgtcg gcacctatgt acttcttgaa gttgcgcgta aatactggtc
      241 tgcgcttggc gaagataaaa aaaataattt tcgttttcat catatttcca ctgatgaagt
      301 ttacggcgat ttaccacatc ctgatgaagt tgaaaacagc gttacgttgc cgttatttac
      361 tgaaacgacg gcatatgcgc caagtagccc ctattctgcg tcaaaagcat ccagcgatca
      421 tttagtccgt gcctggcggc gtacctatgg tctaccaacg atcgttacca attgttctaa
      481 taactatggc ccttatcact tccctgaaaa actgattccg ttggtcattt tgaacgcact
      541 ggaaggaaag cctttgccaa tttatggcaa aggggatcag attcgcgatt ggctatatgt
      601 agaagatcac gctcgcgcgc ttcatatggt agtgactgaa ggcaaggcag gggagactta
      661 taacattggt ggccacaatg agaagaaaaa tctcgatgtg gtatttacca tctgtgatct
      721 gctggatgag attgtaccca aagcgacttc ttatcgtgaa caaatcactt atgtcgcgga
      781 tcgtccgggc catgatcgtc gttatgccat tgatgcaggt aaaattagcc gtgaattagg
      841 ctggaaaccg ctggagacct ttgaaagcgg tattcgtaaa acagtggaat ggtaccttgc
      901 aaatactcaa tgggtaaaca atgttaaaag tggggcgtat cagagttgga tagaacagaa
      961 ctatgaagga cgccagtaat gaatatctta ctttttggta agacagggca agtaggctgg
     1021 gagttgcaac gttctctggc gccagtgggg aatctgattg ccctggatgt ccattcaaaa
     1081 gagttttgcg gtgattttag taatccgaaa ggcgttgccg aaaccgttcg taagcttcgt
     1141 cccgatgtga ttgttaacgc agcagcacat actgcagtag ataaagcaga gtctgaacca
     1201 gaactggcgc agttgcttaa cgccaccagt gtggaagcca tcgctaaagc ggccaacgaa
     1261 attggcgcat gggtagtgca ttattcaacc gattatgtat ttcctggtac cggcgatatc
     1321 ccatggcagg aaacggacgc tacgtcgccg ctgaatgtct atggcaagac caaactagcg
     1381 ggagaaaagg ccctgcagga taactgccct aaatacctaa tcttccgcac cagttgggtt
     1441 tatgcaggta agggcaataa tttcgcaaag acaatgcttc gtctggcgaa agagcgtcag
     1501 acactttcag tcatcaacga tcagtacggt gcgccaaccg gtgcggaatt actggctgac
     1561 tgcacggctc atgcgatccg tgtgacatta aataaaccag aagtcgcagg tctttaccat
     1621 ctggttgccg ggggaactac aacctggcat gactacgcgg cgttagtctt tgacgaggcg
     1681 cgcaaagcag ggataacgct tgcgctgact gagcttaatg ctgtgccgac cagcgcctac
     1741 ccgacgccgg cgagcagacc tggtaattcg cgtctcaata ctgaaaagtt tcagcgtaat
     1801 tttggcctta ttctgccgca atgggaatta ggagttaagc gtatgctgac tgaaatgttt
     1861 acgacgacaa ccatctgata aatttaaatg cccataaggg cattttctat gaatgagaaa
     1921 tggaaatgaa aacgcgtaag ggcattattt tagcgggagg ctccggcact cgtctttatc
     1981 cggtgaccat ggcggtaagt aagcaattgc taccaattta tgataaaccg atgatttact
     2041 atcccctttc cacacttatg ctggcaggca ttcgggatat cctgatcatc agtacgccac
     2101 aggacacgcc gcgttttcaa caactgctgg gagacggcag ccaatggggg ctgaatcttc
     2161 aatataaagt acagccaagt ccggatggct tagcacaggc gtttattatt ggtgaagagt
     2221 tcattggtaa taatgattgt gcattagtgc tgggtgacaa tatcttctat ggtcatgatt
     2281 taccaaagtt aatggaagct gccgttaata aagaaagtgg tgctaccgtc ttcgcttatc
     2341 atgtaaacga tccagagcgc tacggtgtgg ttgagtttga ccaaaatggc acagccgtta
     2401 gtctggagga aaaaccgtta caaccgaaga gtaattacgc ggtaacgggg ctgtattttt
     2461 atgataatag cgtggtggag atggcgaaaa atcttaagcc ttcctctcgc ggtgagttag
     2521 aaatcacgga tattaaccgt atctatatgg atcagggaag attgtctgtc gctatgatgg
     2581 ggcgcggtta tgcctggctg gatacgggaa cgcatcagag tttgatagag gccagtaatt
     2641 ttattgcaac catcgaagaa cgccagggtc tgaaagtgtc ttgcccggaa gagatcgcat
     2701 ttcgtaaaaa ttttataaat gcacaacagg ttataaaact ggccgggcca ttatcaaaaa
     2761 atgattacgg caaatatttg ctgaagatgg tgaaaggttt ataagtgatg attgtgatta
     2821 aaacagcaat accagatgtc ttgatcttag agcctaaagt ttttggcgat gagaggggat
     2881 tcttttttga aagttataac cagcagacct ttgaagagtc gattggacgt aaagttacat
     2941 ttgttcaaga taatcattca aaatccaaaa agaatgtact cagagggcta cattttcaga
     3001 gaggagaaaa tgcacaggga aagttagttc gctgtgctgt cggtgaggtt tttgatgttg
     3061 cggtcgatat ccgaaaagaa tcacctactt ttggtcagtg ggttggcgta aatctatctg
     3121 ctgagaataa gcgacagctt tggattccag aaggttttgc tcatggtttt gttactctca
     3181 gtgattatgc agagtttctg tacaaagcaa ctaattatta ctcaccttca tcggaaggta
     3241 gcattctatg gaatgatgag acaataggta ttgaatggcc tttttctcag ctgcctgagc
     3301 tttcagcaaa agatgctgca gcacctttac tgcatcaagc cttgttaaca gagtaagcat
     3361 cgtgtctcat attattaaga tttttccatc aaatattgaa ttttccggta gagaggatga
     3421 atcaatcctc gatgctgcgc tatcggctgg catccatctt gaacatagct gcaaagcggg
     3481 tgattgtggt atctgtgagt ccgatttgtt agcgggagaa gttgttgact ccaaaggtaa
     3541 tatttttgga cagggtgata aaatactaac ctgctgctgt aaacctaaaa ccgcccttga
     3601 gctaaatgcg catttttttc ctgaactagc tggacagaca aaaaaaattg tcccatgcaa
     3661 ggtaaatagt gctgtactgg tttcaggcga tgttatgact ttgaagttac gcacaccacc
     3721 aacagcaaaa attggcttct ttccagggca gtatatcaat ttacattata aaggtgtaac
     3781 tcgcagttat tctatcgcta atagtgatga gtcgaatggt attgagttgc atgtaaggaa
     3841 tgttcccaat ggtcagatga gctcgctcat ttttggggag ttacaagaaa atactcttat
     3901 gcgcattgaa ggaccttgcg gaacattttt tattcgtgaa agtgacagac ctataatctt
     3961 ccttgcaggc ggtactggat tcgctccagt taaatcaatg gttgagcatc tcattcaggg
     4021 aaaatgtcgt cgtgagatct acatctactg gggaatgcaa gatagtaaag atttttactc
     4081 tgcattaccg cagcagtgga gtgaacagca cgacaacgtt cattatatcc ctgttgtttc
     4141 tggtgatgac gccgaatggg ggggaagaaa gggatttgtc catcatgctg tgatggatga
     4201 ttttgattct ctagagttct tcgatatata tgcatgtggt tcacctgtga tgatcgatgc
     4261 cagtaaaaag gactttatga tgaaaaatct ctctgtagaa catttctatt ctgatgcatt
     4321 taccgca
//
LOCUS       DAJVBX010000260         4312 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.260, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000260 DAJVBX010000000
VERSION     DAJVBX010000260.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4312
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.260"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(65..517)
                     /locus_tag="OPV72_004172"
     CDS             complement(65..517)
                     /locus_tag="OPV72_004172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system effector protein OrgC"
                     /protein_id="HCR9916320.1"
                     /translation="MIPGTIPTSYLVPTADTEVTGVVSLSARAAMLNNVDSAPLSNGG
                     DVDLYDAFYQRLLALPESASSETLKDSIYQEMNAFKDPKSGDSAFVSFEQQTAMLQNM
                     LAKVEPGTHLYEALNGVLVGTMNAQSQMTSWMQEIILSGGENKEAIDW"
     gene            complement(533..1204)
                     /gene="orgB"
                     /locus_tag="OPV72_004173"
     CDS             complement(533..1204)
                     /gene="orgB"
                     /locus_tag="OPV72_004173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010835247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system linker protein OrgB"
                     /protein_id="HCR9916321.1"
                     /translation="MLKNIPIPSPLSPVEGILIKRKTLERYFSIERLEQQAHQRAKRI
                     LREAEEEAKTLRMYAYQEGYEQGMIDALQQVAAYLTDNQTMAWKWMEKIQIYARELFS
                     AAVDHPETLLTVLDEWLRDFDKPEGQLFLTLPVNAKKEHQKLMVLLMENWPGTFNLKY
                     HQEQRFIMSCGDQIAEFSPEQFVETAVGVIKHHLDELPQDCRTISDNAINALIDEWKT
                     KTQAL"
     gene            complement(1161..1760)
                     /gene="orgA"
                     /locus_tag="OPV72_004174"
     CDS             complement(1161..1760)
                     /gene="orgA"
                     /locus_tag="OPV72_004174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-regulated invasion protein OrgA"
                     /protein_id="HCR9916322.1"
                     /translation="MIRRNRQMNRQPLPIIWQRIIFDPLSYIHPQRLQIAPEMIVRPA
                     ARAAANELILATWRLKNGEKECIQNSLTQLWLRQWRRLPQVAYLLGCHKLRADLARQG
                     ALLGLPDWAQAFLAMHQGTSLSVCNKAPNHRFLLSVGYAQLNALNEFLPESLAQRFPL
                     LFPPFIEEALKQDAVEMSILLLALQYAQKYPNSVPAFAC"
     gene            complement(1732..2490)
                     /gene="prgK"
                     /locus_tag="OPV72_004175"
     CDS             complement(1732..2490)
                     /gene="prgK"
                     /locus_tag="OPV72_004175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system inner membrane ring
                     lipoprotein PrgK"
                     /protein_id="HCR9916323.1"
                     /translation="MIRRYLYTFLLVMTLAGCKDKDLLKGLDQEQANEVIAVLQMHNI
                     EANKIDSGKLGYSITVAEPDFTAAVYWIKTYQLPPRPRVEIAQMFPADSLVSSPRAEK
                     ARLYSAIEQRLEQSLQTMEGVLSARVHISYDIDAGENGRPPKPVHLSALAVYERGSPL
                     AHQISDIKRFLKNSFADVDYDNISVVLSERSDAQLQAPGTPVKRNSFATSWIVLIILL
                     SVMSAGSGVWYYKNHYARNKKGITADDKAKSSNE"
     gene            complement(2487..2792)
                     /gene="prgJ"
                     /locus_tag="OPV72_004176"
     CDS             complement(2487..2792)
                     /gene="prgJ"
                     /locus_tag="OPV72_004176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system inner rod protein
                     PrgJ"
                     /protein_id="HCR9916324.1"
                     /translation="MSIATIVPENAVIGQAVNIRPMETDIVSLDDRLLQAFSGSAIAT
                     AVDKQTITNRIEDPNLVTDPNELAISQEMISDYNLYVSMVSTLTRKGVGAVETLLRS"
     gene            complement(2811..3053)
                     /gene="prgI"
                     /locus_tag="OPV72_004177"
     CDS             complement(2811..3053)
                     /gene="prgI"
                     /locus_tag="OPV72_004177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system needle filament
                     protein PrgI"
                     /protein_id="HCR9916325.1"
                     /translation="MPTSWSGYLDEVSAKFDKGVDNLQTQVTEALDKLAAKPSDPALL
                     AAYQSKLSEYNLYRNAQSNTVKVFKDIDAAIIQNFR"
     gene            complement(3078..4256)
                     /gene="prgH"
                     /locus_tag="OPV72_004178"
     CDS             complement(3078..4256)
                     /gene="prgH"
                     /locus_tag="OPV72_004178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system inner membrane ring
                     protein PrgH"
                     /protein_id="HCR9916326.1"
                     /translation="METSKEKTITSPGPYIVRLLNSSLNGCEFPLLTGRTLFVVGQSD
                     ALTASGQLPDIPADSFFIPLDHGGVNFEIQVDTDATEIILHELKEGNPESRSVQLNTP
                     IQVGELLILIRPESEPWVPEQPEKLETSAKKNEPRFKNGIVAALAGFFILGIGTVGTL
                     WILNSPQRQAAELDSLLGQEKERFQVLPGRDKMLYVAAQNERDTLWARQVLARGDYDK
                     NARVINENEENKRISTWLDTYYPQLAYYRLHFDEPRKPVFWLSRQRNTMSKKELEVLS
                     QKLRALMPYADSVNITLMDDVTAAGQAEAGLKQQALPYSRRNHKGGVTFVIQGALDDV
                     EILRARQFVDSYYRTWGGRYVQFAIELKDDWLKGRSFQYGAEGYIKMSPGHWYFPSPL
                     "
BASE COUNT         1110 a         1108 c          907 g         1187 t
ORIGIN      
        1 attttctgca ttatttgctg atatatacac cataccttat cacaaatcgc cagcaatggg
       61 gggttcacca gtcaattgcc tctttgtttt ccccgcccga taaaataatc tcctgcatcc
      121 aggaggtcat ttgtgactgt gcattcattg taccaactaa taccccgttt aaagcctcat
      181 ataaatgggt gcccggttca acttttgcta acatgttttg tagcatagcc gtttgctgct
      241 caaaagaaac aaaagccgaa tcaccacttt taggatcttt gaaggcattc atctcttgat
      301 aaatgctatc tttaagcgtt tcagaagagg ctgactcagg aagcgccaaa agtcgttggt
      361 agaatgcatc ataaagatca acgtcgccgc cattgcttaa aggcgcgcta tccacattat
      421 tcagcatagc ggccctggca ctcaacgaaa ccacacccgt cacttcagta tccgctgtcg
      481 ggaccaaata agaagtcgga atcgtacccg gtatcacctt ataacctcca ttttacaatg
      541 cttgcgtttt tgtcttccat tcatcaataa gtgcgttaat ggcgttatca gaaatcgtcc
      601 ggcagtcttg tggaagttca tcaagatgat gcttaatgac gcctactgct gtttcaacaa
      661 attgttcagg tgaaaattct gcgatctgat cgccgcaact catgataaag cgctgttcct
      721 gatgatattt aagattaaaa gtgccaggcc agttctccat aagcaacacc atcagttttt
      781 ggtgttcttt tttcgcatta actggcagtg ttaaaaaaag ttgcccctcc ggcttatcga
      841 aatcccttag ccactcatcc aggacggtta aaagcgtttc gggatggtcg accgctgctg
      901 aaaataactc gcgggcataa atctgtattt tttccatcca cttccaggcc attgtctgat
      961 tatcagtaag ataagcggcg acctgctgta acgcgtctat cattccctgc tcgtaacctt
     1021 cctgataggc gtacatccgc aaggtctttg cctcttcttc cgcctctcgc aaaatacgct
     1081 tagcccgttg gtgcgcctgc tgttctaatc tttcaataga gaaataacgt tccagcgttt
     1141 tacgctttat cagtatcccc tcaacaggcg aaagcgggga cggaattggg atatttttga
     1201 gcatattgta aggccagtag caaaattgac atttctacag catcctgctt caatgcctcc
     1261 tcaataaatg gaggaaaaag caaaggaaaa cgctgtgcta aagattcagg taaaaattca
     1321 ttcagggcat ttaactgtgc atacccgacg ctaagtaaaa acctgtgatt cggcgcctta
     1381 ttgcaaacgg ataaacttgt tccctgatgc attgccaaaa atgcttgcgc ccaatccggc
     1441 aggccaagca aggctccctg ccttgccaga tcggctctca gtttatggca accgagtaaa
     1501 tacgctactt gcggcagtcg gcgccactga cgcagccaca gctgcgtcag tgagttttga
     1561 atacactcct tttctccgtt cttaagccgc catgtcgcca gtattaactc atttgccgcc
     1621 gccctggcgg cgggtctgac aatcatttcc ggcgctatct gcaaccgctg aggatggata
     1681 tacgataacg gatcaaaaat gattctttgc cagataatgg gtaatggctg cctattcatt
     1741 tgacgatttc gccttatcat cagccgttat gcctttctta ttgcgggcat aatggttttt
     1801 gtaataccag acgccagagc ctgctgacat cacggataac aaaataatca acacaatcca
     1861 actggttgca aaagaattac gttttactgg tgtgccggga gcctgtaatt gggcatcaga
     1921 acgttctgac aacacaacag aaatgttgtc ataatccaca tcggcaaaac tattctttaa
     1981 gaaacgcttg atatcgctga tctgatgcgc aagcggcgaa cctcgttcat atacggctaa
     2041 tgccgacaga tgaacaggtt ttggcggacg gccattttca ccagcatcaa tatcataact
     2101 aatatggacc ctggcggaga gcacgccctc catcgtctgt aatgactgtt ccagtcgctg
     2161 ttcaatagcc gaatataacc tggccttttc agctcgcgga gacgatacca gcgaatccgc
     2221 cgggaacatc tgcgctattt ccacccgtgg ccggggagga agctgataag ttttaatcca
     2281 gtacaccgca gcggtaaaat caggctcagc aacggtaatg ctatagccca attttccgct
     2341 atcaatttta ttcgcctcta tattgtgcat ttgcagaacg gcaatgacct cattagcctg
     2401 ttcctggtcc agtcctttta aaagatcctt atccttacag ccggcaaggg tcattaccag
     2461 cagaaaggta tatagatatc gacgaatcat gagcgtaata gcgtttcaac agccccgact
     2521 cctttacgag taagggtact taccatagaa acatacaggt tataatctga aatcatctct
     2581 tgcgaaatag ccagctcatt aggatccgtc accagattag ggtcctcaat cctgttggta
     2641 atcgtctgtt tatccacagc cgtggcaatc gccgaaccag aaaaagcctg gagtagccgg
     2701 tcatccagcg agacaatgtc cgtttccata ggcctgatat tgaccgcctg ccctataacg
     2761 gcattctcag ggacaatagt tgcaatcgac ataatccacc ttataactga ttaacggaag
     2821 ttctgaataa tggcagcatc aatatcctta aagactttta ccgtgttcga ttgcgcgtta
     2881 cggtacaagt tatattccga gagcttactc tgatacgccg ccagtagcgc cggatcggag
     2941 ggttttgctg ctaatttatc cagcgcctct gttacctgcg tttgtagatt atcaacgccc
     3001 ttatcaaatt ttgctgaaac ttcatccaga tagcctgacc aagatgttgg cataatgact
     3061 tccttatttg cgttaaatta aagtgggctt gggaaatacc aatggcctgg gctcattttg
     3121 atataacctt ccgccccgta ctgaaatgag cgccccttga gccagtcatc ttttaattcg
     3181 atcgcaaact gcacatagcg tcctccccat gtgcggtaat agctatcgac aaattgacgg
     3241 gctctgagta tttctacatc atcgagcgcc ccctgaataa caaacgttac gcccccctta
     3301 tgattcctgc gggaataagg taacgcctgc tgttttagcc ccgcttccgc ctggcctgcg
     3361 gcggtaacat cgtccatcaa tgtgatgtta accgaatccg cgtaaggcat tagcgctctc
     3421 agcttttgac ttaacacctc gagctctttc ttgctcatcg tgtttcgctg gcggcttagc
     3481 cagaaaacgg gtttacgcgg ctcatcgaaa tgaagccgat aataagccag ctgcggataa
     3541 taggtatcca gccaggtaga gatacgctta ttttcttcgt tttcgttaat cactcgcgca
     3601 tttttatcat aatcgcccct cgctaaaacc tgacgagccc acagcgtatc tctttcattt
     3661 tgcgcagcga catagagcat tttgtcccgt cctggcaaca cctgaaagcg ctccttctcc
     3721 tgccccaata acgaatcgag ctctgcggcc tgccgctgcg gcgagttaag tatccataac
     3781 gtccccaccg tcccaattcc caatataaaa aacccggcca gtgctgctac aattccgttt
     3841 ttaaaacgcg gctcgttctt ttttgcagac gtttctaact tctcaggctg ctcgggcacc
     3901 cacggctcgc tttccgggcg aatcaggata agcaattcac cgacctgtat tggcgtattt
     3961 aattgcaccg aacgagattc aggatttcct tctttcagct catggagtat aatttcggtc
     4021 gcatccgtat ccacctggat ttcaaaattt actccgccat ggtccagcgg gataaaaaag
     4081 ctatcggcag gtatatcagg gagttggcct gaagcagtga gcgcatcact ctgacctacc
     4141 acaaagagtg ttcggcctgt cagcaatgga aactcacagc cgttcagtga gctgttaagt
     4201 aatcgaacta tgtatggccc tgggcttgtt atcgtcttct cttttgatgt ttccatatat
     4261 actgttagcg atatctgtcg ttctcgatag cagcagatta ccgcacagga ca
//
LOCUS       DAJVBX010000261         4270 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.261, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000261 DAJVBX010000000
VERSION     DAJVBX010000261.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4270)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4270)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4270
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.261"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(50..712)
                     /locus_tag="OPV72_004179"
     CDS             complement(50..712)
                     /locus_tag="OPV72_004179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001576082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCR9916327.1"
                     /translation="MKHTQQSGAKVYNPFTLSLYDWWVLNISNKYAWKCPTDTRLLPF
                     FLHHMGETHLDIGVGTGYYLKHAPATHAISLMDLNPDSLKIAASRVGNTKIRATLQHD
                     VFDTFPADWHGRFDSVSMYYLLHCLPGEMTTKAKAIKNAGMALKPGGTLFGATILGKE
                     VPHNAFGKKLMAVYNKKGIFSNTNDSADTLRSVLDEHFAKVTLEQHGAVALFSATMPR
                     SL"
     gene            complement(1176..2726)
                     /locus_tag="OPV72_004180"
     CDS             complement(1176..2726)
                     /locus_tag="OPV72_004180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 39 protein"
                     /protein_id="HCR9916328.1"
                     /translation="MALPQLSIWQPGDGLRKIKYKYHVCLIVIFSVLIRLLFLTDRYL
                     WCDEASSVLISRHSVDNLLFHAAFDVHPPLYYLLLHDWIILLGDSIAAVRSLSLLFGI
                     LTVVLVIALTRWLANERTALLAGWFAALMPMAVHYSQETRMYALMGMLTLAAALALMM
                     WIKTPTHNRYLVAYALLMTFSFYTHYFTLFTLIAHWIAVTILSCQSHKTACYLKLPGW
                     WFANLAIAVAYLPWLPVLFNLLTHLAQLRAGNDIGWIPPVTWRDLPAMYWHFFTGNNG
                     QGFPSFILWLAVGGFIGTVGRISLYNGEYERYQLILFCNLVIPVMLVFIISWWMPLFI
                     DRYFFFSSLSIPPLLAVLLTRAKKAVCGFWFILFTLLFGYGSYHNNPEHIDEFKPLVN
                     YINTRHQPNDAVVVSKMFDYLSYVYYNKRDYRTFLYTPPNAHGTSGRPNAYGFGSLFY
                     AQADQTYIDTLTTLSKSYHRVWLVSGGNFSQDYPLPSEWQNIAKFRSGRFQVQLFVIP
                     TQQARQMQ"
     gene            complement(2863..3543)
                     /locus_tag="OPV72_004181"
     CDS             complement(2863..3543)
                     /locus_tag="OPV72_004181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HCR9916329.1"
                     /translation="MIAGWSLFFNDLTEQLPLVVDGIKETCKLALIVSITGFLWGIII
                     FFLSLSHRPVVKAITRLYMDFFIGTPLILILFVIYYGLPQSGIHLSSFTVAVTGFTLN
                     VGAYNAAYMTTAYNALNKYETEAAVVQGLNKRQVFLWIILPQVLLSSIPALTNQVINN
                     LKDSTIVFLIQYTEFFARIQEVAATSFKFFHAYLFAAIVYLIGVTFIVGLTRFLEHRL
                     LRHYGQDY"
     gene            complement(3540..4262)
                     /locus_tag="OPV72_004182"
     CDS             complement(3540..4262)
                     /locus_tag="OPV72_004182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013318930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HCR9916330.1"
                     /translation="MELKEISKEYSGKKVLDAVSLKIQSGDMKVVMGPSGCGKTTLLR
                     CLLRLEEPDYGDIYFHGENIYDKEFTILEFRKKVGCVFQNYALYRHLNVMDNITLALC
                     KVFGMPGQLAREKALHELQKLDMVSHSAKYPSQLSGGQQQRVALARTMVTDPELIIFD
                     EPTSALDPLMTREVGMLIKQLHDNGVTILCVTHDIRLARLLSDNVTFLNHGKIRAEGA
                     FTDLALRETDPDIHCFFSEAQR"
BASE COUNT         1320 a          895 c          948 g         1107 t
ORIGIN      
        1 gggttaaacc cacatgatcg cgctgccgac cgcccggaag tgcctacacc tacaatgaac
       61 gtggcatagt ggcggaaaat agcgcaacgg cgccatgttg ctccaaagtc accttagcga
      121 aatgttcgtc caacacgctg cgtaacgtat cggctgaatc attggtatta ctgaatattc
      181 ctttcttgtt ataaacagcc attaatttct taccaaaagc attgtgagga acctctttgc
      241 ccagaatcgt ggcgccaaaa agtgtgccgc cgggttttag cgccataccg gcatttttaa
      301 ttgccttcgc ttttgttgtc atctcaccgg gtaagcagtg cagaagatag tacatcgaaa
      361 cggaatcgaa gcgcccgtgc cagtccgccg ggaacgtgtc gaaaacatcg tgttgtagtg
      421 tggcgcggat tttcgtatta cccactcggc tggcggctat tttcaggcta tccggattta
      481 aatccatcag cgaaatggca tgagtcgcag gtgcatgttt caggtaataa cctgtaccta
      541 cgccaatatc caggtgagtc tcgcccatgt gatgcaggaa gaaaggaagt agtcgcgtat
      601 cagtaggaca cttccaggca tatttgtttg agatattgag tacccaccag tcatataagc
      661 taagcgtgaa tgggttatag acttttgcgc ctgattgttg tgtatgcttc attgttctct
      721 cattaaataa tttcgcgctg gaattaaaac aacgaagtaa tcgttaggca agcattaatc
      781 aggtgagtga gtaatttaat gcgatgaata aaggcgatat tattaattaa acggctatct
      841 taaagaatat agaggataat aatagctgat aaatgaattg gacagtcata ttattataag
      901 ctgataatta ataatcgtta atataaatat attaagcctt atgataatag caatgcaatt
      961 aaatgcatga ggaacaatat ttattcatac acataaagcg attattgcac attaattgat
     1021 attttaaatg ttacgctgag atagccatct ttatttaata tcacctacct ggaggcgata
     1081 tgattgaggt ttttgaagcg tttggctgga ccttactttt aggcggtctg gcagtggcag
     1141 tactgtttat cactgcactg gatagaaaac ggtaatcatt gcatttgacg cgcctgttga
     1201 gttggtatta caaataattg tacctgaaat ctaccacttc tgaattttgc gatattttgc
     1261 cattctgacg gcaaggggta atcctgactg aagttaccgc cgcttaccaa ccagacacga
     1321 tggtaacttt ttgaaagcgt tgtcagagta tcaatatatg tctgatcggc ttgcgcataa
     1381 aacagtgaac caaagccata ggcattcggt cttcctgatg ttccgtgtgc gttaggtggt
     1441 gtataaagaa acgtacgata atctcgctta ttataataca cataacttaa ataatcgaac
     1501 attttactga ctaccacggc atcattaggc tggtgacggg tattaatata gtttaccagt
     1561 ggtttaaact cgtctatgtg ctcagggtta ttatgatatg aaccatagcc gaataataag
     1621 gtgaataaga taaaccagaa gccacaaacc gctttttttg cgcgggtaag taataccgcg
     1681 agcaggggag gaatgctcag cgatgagaag aagaaataac gatcgataaa taacggcatc
     1741 caccaggaaa tgatgaagac cagcattaca gggatgacca gattacaaaa taatatcagc
     1801 tgatatcttt catattctcc gttgtataaa gatattcgcc ccacagtacc gataaaacct
     1861 cccacagcca gccacagaat gaacgacgga aaaccctgtc cgttgtttcc ggtaaaaaaa
     1921 tgccagtaca tcgcaggcag gtcacgccat gttacggggg gaatccaacc gatatcatta
     1981 ccggctctca actgcgccag atgagtcagt aaattaaaca atacgggcaa ccaggggaga
     2041 taagcgacag caatcgccag gttagcaaac caccagccag gaagtttaag gtagcaggcc
     2101 gttttatggc tttggcagga taatattgtt actgcgatcc agtgggcaat aagtgtaaat
     2161 agggtgaaat aatgggtgta aaagctgaac gtcataagta aagcatacgc gacaagatag
     2221 cgattatggg tgggtgtttt tatccacatc atcaatgcta acgcggcagc gagcgttagc
     2281 attcccatta acgcgtacat gcgcgtttct tgactgtaat gaactgccat cggcatcagg
     2341 gcggcgaacc atcccgccaa taaggctgta cgttcatttg ccagccatcg cgtaagcgcg
     2401 ataaccagca caactgtcag gatcccaaag agtagactga gagagcgtac cgctgcaatg
     2461 ctatcaccca ataatatgat ccagtcatgc agtaacagat aataaagcgg gggatgcacg
     2521 tcaaaagcgg catggaagag cagattatct acgctatgtc gactaatcag cacgctggac
     2581 gcttcgtcac accaaaggta gcggtcagtt aaaaacagca accgtataag gacggagaat
     2641 ataacaatga gacaaacatg atatttatac tttatttttc ttaacccatc gccgggctgc
     2701 catatggata gttgtggtag cgccataata tcctcaatgg agtaagactt agaccagaat
     2761 ggacacctaa cgcaataatg aaggttaaaa tcttaaccaa cactaaataa aaataacttt
     2821 gataatgtca gcggtgaatt aatcagaata gtgcagtaca actcagtaat cctgaccgta
     2881 atggcgaagc agtctatgct ctaaaaaccg ggtcaaaccg acaataaagg taacgccaat
     2941 aaggtacact atggcggcaa aaaggtaagc atggaagaat ttaaagctgg ttgcagcaac
     3001 ctcctgaatt cgcgcgaaaa actcagtata ttggataaga aaaacgatgg tgctgtcttt
     3061 aaggttatta atcacctgat tcgttaaggc tggaatggaa gacagcaata cctgaggcag
     3121 tataatccac aaaaagacct gccgtttgtt caacccctga acgactgctg cctccgtttc
     3181 atacttattc aatgcgttat aggccgttgt catgtacgcg gcattatatg cgccgacatt
     3241 caaggtaaaa cctgtaaccg ccacggtaaa agaggacagg tgaatgccag attgaggtaa
     3301 accataatag ataacaaaca gaataagaat gagtggcgta ccgataaaga aatccatgta
     3361 cagtcgagtt atggctttta ccacggggcg atggctcagg ctcagaaaga aaataataat
     3421 tccccacaaa aaaccggtga tggaaacaat cagcgcaagt ttacaggttt ctttaatacc
     3481 gtccacaaca agtggcagtt gttcagtcag gtcattaaag aaaagagacc agccagcgat
     3541 catcgttgtg cctcgctaaa aaaacagtgg atatctggat ccgtttctcg taaggcaaga
     3601 tcggtaaaag cgccttctgc acgaatcttg ccatgattaa gaaacgttac gttatcgctt
     3661 agtaatctgg cgaggcgaat atcatgagtg acgcataata tagtgacgcc attgtcgtga
     3721 agttgcttga tcaacattcc gacttcacga gtcatgagcg gatcaagcgc agacgtcggc
     3781 tcatcaaaaa taatgagttc tgggtcggtg accattgtac gggccagggc gacgcgctgt
     3841 tgctggccac ccgataattg cgaagggtat ttcgcgctat gcgagaccat atcaagtttt
     3901 tgtagctcat gtaaggcttt ctcccgggct agttgtcccg gcatcccaaa cactttacat
     3961 agggcaaggg taatattatc catgacgtta agatggcgat acaatgcgta attctggaag
     4021 acacaaccaa ctttttttct gaactcaaga atagtaaatt ctttgtcgta aatattttcc
     4081 ccgtgaaaat aaatatcgcc ataatcaggt tcttctaatc gaagcagaca gcgtaaaagc
     4141 gtcgtttttc cacaacccga tggccccatg actactttca tgtctcccga ttgaattttc
     4201 aaactaaccg catcaagaac cttttttcct gaatattcct tacttatctc ttttagttcc
     4261 agtaaagcca
//
LOCUS       DAJVBX010000262         4262 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.262, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000262 DAJVBX010000000
VERSION     DAJVBX010000262.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4262
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.262"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            381..1151
                     /gene="garL"
                     /locus_tag="OPV72_004183"
     CDS             381..1151
                     /gene="garL"
                     /locus_tag="OPV72_004183"
                     /EC_number="4.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxyglucarate aldolase"
                     /protein_id="HCR9916331.1"
                     /translation="MNNAIFPNKFKAALAAQQVQIGCWSALASPITTEVLGLAGFDWL
                     VLDGEHAPNDVTTLIPQLMALKGSASAPVVRVPTNEPVIIKRMLDIGFYNFLIPFVET
                     QEEAARAVASTRYPPEGIRGVSVSHRANMFGTVPDYFAQSNKNITIIVQIESQLGVDN
                     VDAIAATEGVDGIFVGPSDLAAALGHLGNASHPDVQQTIQHIFARAKAHGKPCGILAP
                     VEADARRYLEWGATFVAVGSDLGAFRASTQKLADTFKK"
     gene            1177..2067
                     /gene="garR"
                     /locus_tag="OPV72_004184"
     CDS             1177..2067
                     /gene="garR"
                     /locus_tag="OPV72_004184"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HCR9916332.1"
                     /translation="MTMKVGFIGLGIMGKPMSKNLLKAGYSLVVSDRNPEAIADVIAA
                     GAETASTAKAIAEQCDAIITMLPNSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLA
                     SREISDALKAKGVEMLDAPVSGGEPKAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVV
                     HTGDIGAGNVTKLANQVIVALNIAAMSEALTLATKAGVNPDLVYQAIRGGLAGSTVLD
                     AKAPMVMDRNFKPGFRIDLHIKDLANALDTSHGVGAQLPLTAAVMEMMQALRADGHGN
                     DDHSALACYYEKLAKVEVTR"
     gene            2165..3310
                     /gene="garK"
                     /locus_tag="OPV72_004185"
     CDS             2165..3310
                     /gene="garK"
                     /locus_tag="OPV72_004185"
                     /EC_number="2.7.1.165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate 2-kinase"
                     /protein_id="HCR9916333.1"
                     /translation="MKIVIAPDSYKESLSAAEVAQAIEKGFREIFPDAQYVSVPVADG
                     GEGTVEAMIAATQGVERAAWVTGPLGEKVKACWGMSGDGKTAFIEMAAASGLALVPPE
                     KRNPLITTSRGTGELILQALESGASNIIIGIGGSATNDGGAGMMQALGAKLRDANGAD
                     IGYGGGSLHCLSNIDISELDPRLKLCAIRVACDVSNPLIGDNGASRIFGPQKGATEEN
                     IVELDRNLAHYADIIKKSLNVDVKAAPGAGAAGGMGAALMAFLGAELRSGIEIVTAAL
                     NLEEHIHDCTLVVTGEGRIDSQSIRGKVPIGVANVAKKYHKPVIGIAGSLTHDVGIVH
                     HYGIDAVFSVLTRIVTLEEAFRGAFDNIYRASRNVAAALAIGMRSAG"
     gene            3343..3718
                     /gene="rnpB"
                     /locus_tag="OPV72_004186"
     ncRNA           3343..3718
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="OPV72_004186"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
BASE COUNT         1047 a         1010 c         1255 g          950 t
ORIGIN      
        1 gcaaattatg aaatttttta tgtagggcag gcaaagcgta aatgtgtgca ttagcgccca
       61 gtatcatggg cgtatgctca aaaataagcg ttaaataaac cctttttaat gagcgtttgc
      121 acaatgatta tccgacatag gctgtttata ctgaatggcg aattcagtgt atctgacgag
      181 ttatttgaaa atatcatgat aataataaaa gacgataaag atatcagaac ggtatattgt
      241 gctacaggat gtgtaccaca ttagaaatag aatgtggaga cccattctga tttcaaataa
      301 gcatttttat tgtcgttgct ataagtcatg gtggcggcat cacatgtaga gaattaaaga
      361 aataagcgaa ggtataagcg atgaataacg ctattttccc gaataagttt aaagcggcgc
      421 tggcggcgca acaggtgcag attggctgct ggtctgcact ggcaagccca atcaccaccg
      481 aagtactcgg tctggcggga tttgactggc tggtgctgga tggcgaacat gcgccgaacg
      541 atgtgaccac cttaattccg cagttaatgg cattgaaagg cagcgccagc gcgcctgtgg
      601 tacgtgtgcc aaccaatgaa ccggtcatta tcaaacggat gctggatatt gggttttata
      661 acttcctgat cccctttgtt gaaacgcaag aggaagcggc tcgcgccgtc gcctcgacgc
      721 gttacccgcc ggaaggcatt cgcggcgtct ccgtttctca ccgcgcgaat atgttcggca
      781 cggtgcctga ttactttgcg cagtcgaaca aaaacatcac cattattgtt caaatcgaaa
      841 gccagttggg tgtcgacaat gttgatgcca tcgccgcaac ggaaggcgtt gatggcattt
      901 ttgtcggccc tagcgatttg gccgccgcgc tgggtcatct cggcaatgct tctcaccctg
      961 acgtgcagca gacgattcaa catattttcg cccgcgctaa agcgcacggt aaaccgtgcg
     1021 gcattctggc gccggtagag gcggatgccc gccgttatct ggaatggggc gcgacctttg
     1081 tcgccgttgg cagcgattta ggcgcattcc gcgccagcac gcagaagctt gccgacacct
     1141 ttaaaaaata atcctggtat ggaaagagag aacgctatga cgatgaaagt tggctttatt
     1201 ggcttaggca tcatgggtaa gcccatgagc aaaaacttac tgaaagcagg gtattcgctg
     1261 gtggtgtccg atcgtaatcc tgaagcgatt gccgacgtca ttgccgcagg cgcggaaacg
     1321 gcctctacgg cgaaggcgat cgctgaacag tgtgacgcca tcatcacgat gctgcctaac
     1381 tctccgcatg tgaaagaggt tgcgctgggc gagaacggta tcatcgaagg cgcgaagccg
     1441 ggaaccgtat tgattgatat gagttctatc gcgccgctgg caagccgtga aatcagcgat
     1501 gcgctgaagg cgaagggcgt tgagatgttg gatgcgccgg tcagcggcgg cgagccgaag
     1561 gcgattgatg gcacgctgtc ggtgatggtg gggggcgata aagccatttt cgacaagtac
     1621 tacgacctga tgaaagcgat ggcgggttcc gtggtgcata ccggcgatat cggcgcaggc
     1681 aacgtcacaa aactggctaa ccaggtgatc gtggcgttga atatcgccgc catgtctgaa
     1741 gcgctgacgc tggcgactaa agcgggcgtc aacccggatt tggtctatca ggcgattcgt
     1801 ggcggtctgg ctggcagcac ggtactggat gcgaaagcgc cgatggtcat ggacagaaac
     1861 tttaagccag gtttccgtat cgatctgcac attaaagatc tggcgaatgc gctggatacc
     1921 tcccacggcg ttggcgcgca gctcccgctg accgccgccg ttatggaaat gatgcaggcg
     1981 ttacgcgcgg atggacacgg taatgacgac catagcgcgc tggcgtgcta ctacgaaaaa
     2041 ctggcgaaag tggaagtcac tcgctaacga cgttgtgccc ggatggcgtg tagcgatccg
     2101 ggcctgaatt tcaggctgga taagtgaaac gccatccggc gttgtgcagt aacaggctac
     2161 cactatgaaa atcgtaattg cccccgactc ctataaagaa agcctttctg ccgccgaggt
     2221 agcgcaggcg atagaaaaag gatttcggga aattttcccc gatgcgcaat atgtctctgt
     2281 tccggttgcc gatggcggcg aaggaacggt cgaagccatg attgccgcga cgcagggcgt
     2341 tgaacgcgcc gcatgggtga ccgggccgtt gggtgaaaaa gtgaaagcct gctggggaat
     2401 gtccggggat ggtaaaaccg cgtttattga aatggcggcg gccagcggac tggcgctggt
     2461 tccgccagaa aaacgcaacc ctttgattac tacctcgcgg ggaacggggg agctgatatt
     2521 gcaggcgctg gaaagcggcg caagcaatat cattataggc attggcggca gcgcgacaaa
     2581 tgacggcggc gcagggatga tgcaggcgtt aggcgcaaaa ctgcgcgatg caaacggcgc
     2641 ggatattggt tacggtggcg gaagccttca ttgtctaagc aacattgata tttcagagct
     2701 cgatccccgt ttaaaactct gcgctattcg tgtcgcttgc gatgtctcca atcctcttat
     2761 cggcgacaat ggcgcatcac gaatttttgg gccgcagaaa ggcgcgaccg aagagaacat
     2821 tgttgagctg gacaggaatc ttgctcatta tgccgacatc ataaaaaaat cgctgaatgt
     2881 cgacgtaaag gcggcgcccg gcgcaggcgc ggcaggcggt atgggggcgg cgttaatggc
     2941 ttttctcggt gcggaattac gcagcgggat cgaaattgtc acggcggcac tgaacctgga
     3001 ggagcatatc cacgactgta cgctggtggt gacgggagaa gggcggattg atagccaaag
     3061 cattcgcggt aaagtgccga ttggcgtcgc gaatgtggcg aaaaaatatc ataagccagt
     3121 gattggcatt gccggcagcc tgacgcacga tgtaggaata gtacatcatt atggcatcga
     3181 cgctgtcttt agcgtactca cgcgcatcgt gacgctggag gaggcttttc ggggcgcttt
     3241 tgacaatatt tatcgggcat ccagaaatgt tgctgccgct ctggcgatag gaatgcgcag
     3301 cgcagggtga caaagtcgcg cgaaccctct atactgcgcg ccgaagctga ccagacagtc
     3361 gccgcttcgt cgtcgtcctt tcggggagac gggcggaggg gaggaaagtc cgggctccat
     3421 agggcagggt gccaggtaac gcctgggggg ggaaacccac gaccagtgca acagagagca
     3481 aaccgccgat ggcccacgca agtgggatca ggtaagggtg aaagggtgcg gtaagagcgc
     3541 accgcgcggc tggtaacagt ccgtggcacg gtaaactcca cccggagcaa ggccaaatag
     3601 gggttcataa ggtacggccc gtactgaacc cgggtaggct gcttgagcca gtgagcgatt
     3661 gctggcctag atgaatgact gtccacgaca gaacccggct tatcggtcag tttcacttct
     3721 tcataaaacc cgcttcggcg ggtttttgct tttacagggc ggcaggatga atgactgtcc
     3781 acgacgctat acccaaaaga aagcggctta tcggtcagtt tcacttcttc ataaaacccg
     3841 cttcggcggg tttttgcttt tacagggcga caggatgaat gactgtccac aacactatac
     3901 ccaaaagaaa gcggcttatc ggtcagtttc acctcttcat aaaccccgtc agtgtaagct
     3961 ggcgggtttt tgcttttaca gggcggcagg atgaatgact gtccacgacg ctatacccga
     4021 aagaaagcgg cttatcggtc agtttcacct cttcataaaa tccgcttcgg cgggtttttg
     4081 cttatcaggc cggtgaaggg tatagaggtt gcagaagacg ccagtgtcac catccggcaa
     4141 ttaattgaca gccgtggtga cataatatta ttcgtttttg tgatgagaaa cacaaaacgc
     4201 tatggattgc gctcttttta gttgaagtga aaagcaatcg atttctttca caaaattaca
     4261 tc
//
LOCUS       DAJVBX010000263         4223 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.263, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000263 DAJVBX010000000
VERSION     DAJVBX010000263.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4223
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.263"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            273..416
                     /locus_tag="OPV72_004187"
     CDS             273..416
                     /locus_tag="OPV72_004187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YobF family protein"
                     /protein_id="HCR9916334.1"
                     /translation="MCGIFSKEVLSKHVDVEYRFSAEPYISASSSNVSVLSMLCLRAK
                     KTL"
     gene            429..638
                     /gene="cspE"
                     /locus_tag="OPV72_004188"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
     CDS             429..638
                     /gene="cspE"
                     /locus_tag="OPV72_004188"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator/RNA stability
                     regulator CspE"
                     /protein_id="HCR9916335.1"
                     /translation="MAKIKGQVKWFNESKGFGFITPADGSKDVFVHFSAIQGNGFKTL
                     AEGQNVEFEIQDGQKGPAAVNVTAI"
     gene            858..2603
                     /gene="ftsI"
                     /locus_tag="OPV72_004189"
     CDS             858..2603
                     /gene="ftsI"
                     /locus_tag="OPV72_004189"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase FtsI"
                     /protein_id="HCR9916336.1"
                     /translation="MKKKSDGDTRNFTPIRFALLCTAILLSMALLLGRVAWLQIVTPS
                     KLVKQEDMRSLREVTTASPRGMITDREGRPLAVSVPVNAVWADPKTIISKGGVGYNER
                     WQALASALHLSLSTLAERVNSNPAGRFIYLARQVSPQQAEWIDKLNLPGINLREESRR
                     FYPAGHVAANLIGFTNIDGQGIEGIEKSFNAQLTGKPGSRLVRKDKFGHVIENITEVN
                     PVPAHELQLSIDERLQTVTEDALDNAVIWNKAESGAAVLINIPTGEILSMASYPDFNP
                     NNREGAQLDDFRNRAISDTFEPGSTVKPLVIMTALQQGIVQPDSVIDTHPFTLDGHRI
                     RDVGYYPELTLTGILQKSSDTGVSHLSLAMPVQKLMDTYKSFGFGVPTGLGLTGESSG
                     LLPKRRYWSDLDRATFAFGYGLMVTPLQLAHVYATIGSFGIYRPLSITKVDPPVIGTR
                     VMPEELVHEVEHMMESVALPGGGGTKAAVRDYRIAVKTGTAKKIGDDGKYVDKYVAYT
                     AGVAPASNPRFALVVVINNPQNGAYYGGAVSAPVFSQIMGDVLRLENVEPDGMPADSD
                     HLLVMHGSHVAVPGS"
     gene            2669..3478
                     /gene="rlmA"
                     /locus_tag="OPV72_004190"
     CDS             2669..3478
                     /gene="rlmA"
                     /locus_tag="OPV72_004190"
                     /EC_number="2.1.1.187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (guanine(745)-N(1))-methyltransferase"
                     /protein_id="HCR9916337.1"
                     /translation="MSFTCPLCHQPLTQINSSVICPQRHQFDVAKEGYINLLPVQHKR
                     SRDPGDSAEMMQARRAFLDAGHYQPLRDAVINLLRERLDQSATAILDIGCGEGYYTHA
                     FAEALPGVTTFGLDVAKTAIKAAAKRYSQVKFCVASSHRLPFADASMDAVIRIYAPCK
                     AQELARVVKPGGWVVTATPGPHHLMELKGLIYDEVRLHAPYTEQLDGFTLQQSTRLAY
                     HMQLTAEAAVALLQMTPFAWRARPDVWEQLAASAGLSCQTDFNLHLWQRNR"
     gene            complement(3475..4041)
                     /gene="mntP"
                     /locus_tag="OPV72_004191"
     CDS             complement(3475..4041)
                     /gene="mntP"
                     /locus_tag="OPV72_004191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416335.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese efflux pump MntP"
                     /protein_id="HCR9916338.1"
                     /translation="MHFTATVLLAFGMSMDAFAASIGKGATLHKPKFSEALRTGLIFG
                     AVETLTPLIGWGLGILASKFVLEWNHWIAFVLLIFLGGRMIIEGIRGGSDEDETPLRR
                     HSFWLLVTTAIATSLDAMAVGVGLAFLQVNIIATALAIGCATLIMSTLGMMIGRFIGP
                     MLGKRAEILGGVVLIGIGVQILWTHFHG"
BASE COUNT         1031 a         1035 c         1134 g         1023 t
ORIGIN      
        1 gaaaaataca gcttttaaat gtgatttgat gcactggaag aagcgaaatt attgagctat
       61 ggtagaaaaa tggcttttca gcagtgacgt tgtcaggagt ccgtcagcgc gtgaggatat
      121 atctttcgca attttgttgc ataaacgtgt tgtcaatttg tgaaggttct cgtaatttgt
      181 gcgacggatc gagacacgtt taaaaatggc ttgccataat taacgttata tgtgataaca
      241 ggctttgggt taaacgaggt acagttctgt ttatgtgtgg cattttcagt aaagaagtcc
      301 tgagtaaaca cgttgacgtt gaataccgct tctctgccga accttatatt agtgcctcaa
      361 gcagtaatgt ctcagtttta tctatgttat gcctacgggc aaagaaaaca ctctaaggaa
      421 ttttgcaaat ggcaaagatt aaaggtcaag ttaagtggtt caacgaatcc aaaggttttg
      481 gcttcattac tccggctgac ggcagcaaag atgtgttcgt acacttctcc gctatccagg
      541 gcaatggttt caaaactctg gctgaaggcc agaacgttga gttcgaaatt caggacggcc
      601 agaaaggtcc ggctgctgtt aacgtaacag ctatctgatc gacaccactg atttgatgcg
      661 tttgtcgcgt cagcctcaga tataaagcct cgctaaaagc ggggcttttt aattcaatat
      721 ccttcaaaat gtgtctggat gcgctctcgt tagcgatttg ttgcaaaggc gcgatgttat
      781 tagcattgtt ttttctggtt tttccggccg tttcccgtta aatcaatcac ctgaaaaatg
      841 attcggctgg agatcaggtg aaaaagaaaa gcgacggcga tacccgtaat tttacaccca
      901 tacgttttgc actactttgc actgccattc tgctcagtat ggcattgttg ttagggcggg
      961 tggcatggct gcaaattgtt acgccgtcga aactggtgaa acaagaagat atgcgctcgc
     1021 ttcgtgaagt gaccacggcc tctccacgcg gcatgatcac cgacagagaa gggcggccct
     1081 tagcggtgag cgttccggtt aatgctgtct gggccgatcc gaaaactatc ataagcaaag
     1141 gcggcgttgg ctacaatgag cgctggcagg cgctggccag cgccttacat ctgtctctca
     1201 gtacgcttgc ggaacgggta aacagtaacc cggcaggtcg ttttatctac ctcgcgcgcc
     1261 aggtttcacc ccagcaagcc gaatggatag ataaactgaa tctaccgggt attaacctgc
     1321 gggaagagtc gcgccgtttt taccctgccg gacatgtagc ggccaatttg atcggcttta
     1381 ccaatatcga cgggcaggga atagaaggta ttgaaaagag ctttaacgcg caactgacgg
     1441 gaaaaccggg ctcccggctg gtgcgtaaag ataaatttgg tcacgttatt gagaacatta
     1501 cggaagtgaa tccggttcct gctcatgaac ttcagcttag cattgatgaa cgtctgcaaa
     1561 cggttaccga agatgcgctg gataacgccg tcatctggaa caaagcggaa tccggcgctg
     1621 ccgtattgat taacatccca acgggtgaaa ttctctcgat ggcgagctac ccggatttca
     1681 acccgaacaa ccgtgaaggc gcgcagttgg acgattttcg taaccgcgcg attagcgaca
     1741 ctttcgaacc cggttctact gtgaagccat tggtcattat gactgcgtta cagcagggta
     1801 tcgtgcaacc ggacagcgtt atcgataccc atccttttac tctcgatgga caccgtatcc
     1861 gcgacgtcgg ctactatccg gaactgacat taaccggcat tttgcaaaaa tccagcgata
     1921 ccggcgtttc tcacctttct ctggcgatgc cggtgcagaa attaatggat acttataaaa
     1981 gctttggttt cggcgtgcct accggactgg gtctcaccgg agagagcagc gggttattac
     2041 cgaaacgccg ttactggagt gatttagatc gcgctacctt cgcttttggc tatggattaa
     2101 tggtgacgcc gctgcaactg gcgcatgttt atgccacgat tggcagcttt ggtatctacc
     2161 gtccgttatc gatcaccaaa gttgatccgc ccgtgatcgg cacgcgagta atgccggaag
     2221 aactggtgca cgaggtggaa catatgatgg agagcgtcgc gttgcctggc ggcggcggaa
     2281 caaaagccgc agtaagagac taccgtattg cggtcaaaac cgggacggcg aaaaaaattg
     2341 gcgatgatgg taaatacgtt gataagtatg tggcatatac cgcaggcgtc gcgccggcaa
     2401 gtaaccccag atttgcgctg gtggtggtga ttaataatcc acaaaatggg gcttattatg
     2461 gcggtgcggt atctgcgccc gtattcagcc agatcatggg cgatgtactg cggctggaaa
     2521 atgttgagcc agacggtatg ccagccgatt cagatcacct tctggtgatg catggcagcc
     2581 acgttgcggt tccgggctcg taaaggattt tcccggggcg caattcgcgt tacacttgcg
     2641 ccctttagcg ccccagtccg gagttgtcat gtcgtttacc tgtccgcttt gccatcaacc
     2701 gcttacgcag attaatagca gcgttatatg tccacagcgc catcagtttg atgtggcgaa
     2761 agagggctac atcaatctgc tgccggtaca gcataaacgt tcgcgcgatc cgggcgacag
     2821 cgccgaaatg atgcaggcga ggagagcgtt tcttgatgca ggccattatc agccgctgcg
     2881 cgatgcggtg attaacctgt tgcgcgagcg gctggatcag tcggccacgg cgattctgga
     2941 tattggctgc ggcgaggggt attacactca tgcttttgcc gaggcgttgc cgggagttac
     3001 cacgtttgga ctggacgttg ctaaaacggc gatcaaagcg gcggcgaagc gctattcgca
     3061 ggtgaagttt tgtgtggcgt caagccatcg actgcccttt gccgatgcgt caatggatgc
     3121 ggtgatcaga atctacgctc cgtgtaaggc gcaggaattg gcgcgtgtgg tgaaacctgg
     3181 tggttgggtc gttaccgcca cgccggggcc gcatcatctg atggaactaa aagggctcat
     3241 ttatgatgag gtgcgtttac atgcgccgta taccgagcag ctcgacggat tcacattgca
     3301 gcagagtacc cgccttgctt atcacatgca gctcaccgcc gaagcggctg tagcactgtt
     3361 gcaaatgacg ccatttgcct ggcgcgccag accagacgtg tgggaacaac tggctgccag
     3421 cgccggactt agctgccaga cggatttcaa ccttcatctc tggcagcgta accgttaacc
     3481 gtgaaaatgc gtccagagga tctggacgcc aattcctatc agtacgaccc cgccgagaat
     3541 ttcagcacgc ttacccagca ttgggccgat aaagcgaccg atcatcattc cgagggtgga
     3601 catgataagc gtggcgcaac cgatagctaa tgcggttgcg atgatgttta cctgcaaaaa
     3661 cgccagaccg acgccaaccg ccatcgcatc gaggctggtc gcgatagccg tcgtgactaa
     3721 tagccaaaag ctgtgacgac gtaacggtgt ttcatcttca tcactaccgc cgcggatacc
     3781 ttcgatgatc atgcgtccgc ccagaaagat cagcagaaca aaggctatcc agtggttcca
     3841 ttccagaacg aatttactcg ccaatatccc cagcccccag ccgatcaacg gggttagcgt
     3901 ttcaaccgcg ccaaagataa gaccggtacg caacgcttct gagaatttgg gtttatgtag
     3961 ggtggcgcct ttgccaattg atgccgcgaa agcatccatc gacatgccga aagcgagaag
     4021 aacagtagca gtaaagtgca tgacagcgtc ctgaccgggg tatccattaa acacatcact
     4081 gcccccagca aacatgcatg tcgccattct gtgacgaaat acacagcagt tgatgcgcct
     4141 atggtctcgc ctgaccagcg gcggctggtc cgtacgcgcc acgttttgca acgagtatgt
     4201 tgacacgtac atttccggag tct
//
LOCUS       DAJVBX010000264         4201 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.264, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000264 DAJVBX010000000
VERSION     DAJVBX010000264.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4201)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4201)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4201
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.264"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            329..1342
                     /gene="trpS"
                     /locus_tag="OPV72_004192"
     CDS             329..1342
                     /gene="trpS"
                     /locus_tag="OPV72_004192"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HCR9916339.1"
                     /translation="MNTLPIILTGDRPTGSLHLGHYVGSLRQRVALQQDHQQYVLIAD
                     LQGLTDNGSNPQKIRDNIPQVLADYLAVGIDPALTTICLQSALPALAELTVLYMNIVT
                     VARVERNPTVKNEIAQKGFTRSLPVGFMAYPISQAADITAFKAEMVPVGDDQLPMIEQ
                     TNEIVHKMNSLFSSPVLRPCQALLSDTGRLPGIDGSAKMSKSLVNTLLLSASEETIHR
                     AVSAMYTDPNHLKISDPGKIEGNVVFTWLDAFHPDKAKVAAMKAHYQQGGLGDRVCKN
                     ELETCLQELIAPIRERRATFIADKGMLMELLKKGSERAHEVTQKTLQEVKRGLGLPTL
                     FQV"
     gene            complement(1343..2116)
                     /gene="uxuR"
                     /locus_tag="OPV72_004193"
     CDS             complement(1343..2116)
                     /gene="uxuR"
                     /locus_tag="OPV72_004193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Uxu operon transcriptional regulator"
                     /protein_id="HCR9916340.1"
                     /translation="MKSNTSQQRPYQEVGAMIRDLIVQTPYRPGERLPPEREIAERLN
                     VTRTVVREALIMLEIKGLVEVRRGAGIYVLDSADNNEMEGADVNHCNDAGPFELLQAR
                     QLLESNIAEFAALQATREDIIKMRQALQLEERELASSAPGGSESGDMQFHLAIAEATH
                     NSMLVELFRQSWQWRENNPMWLQLHSHLGDTLYRKEWLGDHKQILAALIKKDARAAKL
                     AMWQHLENVKQRLLEFSNVDDIYFDGYLFESWPLDNVDA"
     gene            2466..3131
                     /locus_tag="OPV72_004194"
     CDS             2466..3131
                     /locus_tag="OPV72_004194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HCR9916341.1"
                     /translation="MIKDTVFFAPSVSGGSNASSLSSRHRRAAIILHEIYGINAHIQR
                     AGHEWMTRGFDIYIPALFPHHTPFRYEQQEEAYRHFSANVGFDPAVVTTLLHDLRAQY
                     ETLIVVGYSVGATLAWLSAASGLCDGVICYYGSRIRQYLHLAPLCPALVIIARYEPAF
                     DPRAMRQTLEKRPRVQCKMYDARHGFCDADSATFDAALSHQVMDDVSAFIRDITCANT
                     SPD"
     gene            complement(3148..3609)
                     /locus_tag="OPV72_004195"
     CDS             complement(3148..3609)
                     /locus_tag="OPV72_004195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF302 domain-containing protein"
                     /protein_id="HCR9916342.1"
                     /translation="MSTILKPFLSAVTLMLILIRPGFATEDGAITMVKTYSAYDYLQT
                     RARLMHAVADHGLVLFGEFDHARAAQNVNLKMPPTTVLVFGNPKGGTPLMLAHPELAL
                     DLPFRVLISQQADGRTLVSYHPAETLQRYGLDAADIQALKKLEQLVEKSLH"
     gene            complement(3820..>4201)
                     /locus_tag="OPV72_004196"
     CDS             complement(3820..>4201)
                     /locus_tag="OPV72_004196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HCR9916343.1"
                     /translation="LMEAYNRLMLNDFACVVRECHAVFRSVLLRIHERKSIVYHEQDS
                     LNTLMANLMARGVISAEYVHKFHFLIDVLESEIFLPMAPEKSHHHHAMMLRISEELAC
                     SIYYLTERSIFFLTQRAEEDGVAP"
BASE COUNT         1077 a         1125 c          981 g         1018 t
ORIGIN      
        1 acttgcatca aaaatgcgcc tttcagcgcc acgtattttt gggcagcaaa ttataaaatc
       61 gcgtttcaaa gtcagtgaca tgttctctgt gcaggcgata tgactttatg cccggacgac
      121 acgccagccg ctttaccctt acgtttagtc gtgatacgtt agaccacatg aacacgaaac
      181 gatccaacgc tacgcaacgt catctccgct ggtggctgcc ttcctgaagg cggcacggat
      241 cactatccct ttttaagtag ccgccgaaag gcggctactg cgtttcggga cgtctttcgg
      301 ctttacagta agcataaagg agtccttaat gaacaccctt cctatcattc tgactggcga
      361 tcgccccacc ggctcgctgc acctcggcca ttatgtcggt tcactgcgcc agcgcgtcgc
      421 gctacagcag gatcaccaac agtatgtcct gattgctgac ctgcagggac tcaccgataa
      481 cggcagtaat ccgcaaaaaa tccgcgataa tattccgcaa gtgttagctg actatctggc
      541 cgtcggcatc gatcccgcgc taacgacgat ctgcctgcaa tccgcattac ccgccctcgc
      601 tgaattaacg gtgctgtata tgaatattgt taccgtcgcc cgagtggagc gtaatcctac
      661 ggtaaaaaat gagattgccc aaaaaggctt tacccgttcc ctgccggtcg ggttcatggc
      721 gtatcccatt agccaggcgg cagatatcac cgcctttaag gccgaaatgg taccggttgg
      781 cgacgaccaa ttgcccatga ttgagcaaac gaatgagatc gttcataaga tgaatagtct
      841 tttctcctcg ccggtattgc gaccctgtca ggcgctcctg agcgatacgg gccgtctgcc
      901 aggcattgac ggcagcgcca agatgtcgaa atcgctcgtc aataccctgc ttctttccgc
      961 cagcgaagaa accatccacc gtgcggtcag cgcgatgtac accgatccca atcatttaaa
     1021 aattagcgat ccgggaaaaa tagaaggtaa cgtcgtcttt acgtggctgg atgcgttcca
     1081 tccggataaa gccaaagtcg cggcgatgaa agcacattat caacaaggcg gattaggcga
     1141 tcgtgtctgt aaaaatgagc tggagacctg cctgcaagaa ctgatcgcgc caatacgcga
     1201 acgacgggca acctttattg cagataaggg aatgctaatg gaattactga aaaaaggtag
     1261 cgagcgggcg catgaggtca ctcaaaagac gctacaggaa gtaaaacgtg gactgggtct
     1321 gcccacgcta ttccaggtat aatcaggcat caacgttgtc cagcggccat gactcaaaca
     1381 gatagccatc aaagtagatg tcatcaacat tggaaaactc cagcagacgc tgcttcacgt
     1441 tttccaggtg ctgccacatc gccagcttcg ctgcgcgggc gtctttctta attaacgccg
     1501 cgaggatctg cttatgatcg cccagccact ccttacggta aagcgtatcg cccagatggc
     1561 tatgaagctg gagccacatc ggattatttt cacgccattg ccaggactga cggaagagct
     1621 cgaccaacat actgttatgg gtcgcttcgg caatggccag atgaaactgc atatcgccgc
     1681 tttctgagcc gcccggcgcg ctggaggcga gttctcgctc ttccagttgt aacgcctggc
     1741 gcattttaat gatgtcctcg cgggtggcct gcagagcggc aaattcagcg atattacttt
     1801 ccagcaactg acgcgcctgt aacagttcaa acggcccggc gtcattacag tgattgacgt
     1861 cagcgccttc catctcgtta ttatccgcgc tgtcgagcac gtagatcccg gcgccgcggc
     1921 ggacttcaac cagaccttta atttccagca tgatcagcgc ttcacgcacg acggtacgcg
     1981 tcacattgag cctctcagcg atctctcttt ccggcggcaa gcgctccccg gggcggtacg
     2041 gcgtctgcac aatcagatcc cgtatcattg cgcccacttc ctggtaaggt ctttgctgag
     2101 aagtgtttga tttcatattg gtcgtgcccg tccgatgcga tttcccggta tcagactata
     2161 gcatttgtaa agagggatag cacgcgtagc acaccaaaaa cgcgaaactg gtcaaccaac
     2221 aaaacaataa tgcgccccgt ttcgttagtg aagccagatg aaaggaaagg cagtagacaa
     2281 tacacgactg atgttccacc tttagccctg atgcctgaat atgaacaaca tattggttta
     2341 ccaatataaa atttatcaac caaaaattac gccataaaat gtgtctgtac attgacagga
     2401 acaacgcctc tgacatagcg tgatcggcga aaatccagcc gctctctttg tatcaagaac
     2461 gcgttatgat aaaagacaca gtgtttttcg ccccaagcgt atccggggga agcaacgcct
     2521 ccagtttgtc gagccgccat cgccgggcag cgattattct gcatgaaatt tatggtatta
     2581 acgctcatat ccaacgcgca ggccatgaat ggatgacgcg cggattcgac atctatattc
     2641 ccgcgctgtt tcctcaccat accccctttc gctatgaaca gcaggaggag gcttaccgtc
     2701 acttttcagc aaatgtcggc tttgatcccg ccgtcgttac cacgttactc cacgatctca
     2761 gagcgcagta cgagacgtta atcgtcgtag gatatagcgt cggcgcaacg ctcgcatggc
     2821 taagtgcagc cagtgggtta tgcgatggcg tcatttgcta ttacggttcc cgtatacgcc
     2881 agtaccttca tcttgcgcct ctctgtccgg cactggttat tatcgcgcgt tatgagccgg
     2941 cgtttgatcc ccgcgccatg cgacagacgc tggaaaagcg cccccgggtg cagtgtaaaa
     3001 tgtacgatgc gcggcacggg ttctgtgatg ctgatagcgc caccttcgat gccgccttat
     3061 ctcatcaggt aatggacgat gtgagcgcat ttattcgcga catcacttgt gcaaacacat
     3121 cgcccgattg aagcctgatt ttcagcttta gtggagactt ttttcaacga gctgttccag
     3181 ttttttcaaa gcctgtatgt ctgcggcatc aagaccataa cgttgcagcg tttcagcggg
     3241 gtgataactg actaacgttc gcccatcggc ttgctggcta atgagcaccc gaaacggtaa
     3301 atccagcgcc agttcgggat gcgccagcat gagaggcgtt ccgcctttag gattgccaaa
     3361 gaccagaacc gttgtcggcg gcattttcag gttaacattc tgtgccgctc tggcatggtc
     3421 aaattcccca aataacacca gaccgtgatc ggcgacagcg tgcatcaacc gcgctcgggt
     3481 ctgcaaatag tcataagcgc tgtaggtttt aaccatggtt atcgctccat cctccgttgc
     3541 aaagccaggc cttattaaga ttaacatcag ggttaccgcc gataaaaaag gctttaaaat
     3601 agtactcatt cttctctctc cctgacccaa tacccatgag taaatgcgac acagatgata
     3661 tgcggtttaa aaatcagtca tcgtactgta ccccttatta ttgcactgaa cagctcatca
     3721 ctaaaaaaac agacggcaga acaaaaaatt ccgacgtctg aacaaattta aataacgatg
     3781 atccaatctg actgagcgac agcgcgatca ttattatgat tatggcgcga caccatcctc
     3841 ttcagcccgc tgggtaagaa aaaatatact ccgctcagta agataataaa tactacaggc
     3901 caactcttca gagatacgga gcatcattgc gtggtgatga tgcgactttt ctggcgccat
     3961 cggcagaaat atttctgact ccagcacgtc aattaaaaaa tgaaatttat gtacatattc
     4021 agcagatata acgcctctcg ccatcagatt agccattagt gtatttaaac tatcttgttc
     4081 atgatatacg atactttttc tctcatgaat tctgaggaga acgcttctga agactgcatg
     4141 acattccctt acgacacagg caaaatcatt aagcatcagg cgattatacg cttccataag
     4201 a
//
LOCUS       DAJVBX010000265         4176 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.265, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000265 DAJVBX010000000
VERSION     DAJVBX010000265.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4176
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.265"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            53..169
                     /locus_tag="OPV72_004197"
     CDS             53..169
                     /locus_tag="OPV72_004197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_448342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916344.1"
                     /translation="MINYDVLHINVALAHCRNAINRVKLKHNLIFLQSRSEL"
     gene            166..561
                     /gene="uspC"
                     /locus_tag="OPV72_004198"
     CDS             166..561
                     /gene="uspC"
                     /locus_tag="OPV72_004198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001766287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspC"
                     /protein_id="HCR9916345.1"
                     /translation="MSYTHILVAVAVTPESHQLLAKAVSIARPVQAKVSLITLASDPE
                     LYNQFAAPMMEDLRAVMHEETENFLKMLGEKADYPIEQTFIASGELSQHILAVCRKHH
                     VDLVICGNHNHSFFSRASCSAKVSSAPAR"
     gene            complement(611..2032)
                     /gene="otsA"
                     /locus_tag="OPV72_004199"
     CDS             complement(611..2032)
                     /gene="otsA"
                     /locus_tag="OPV72_004199"
                     /EC_number="2.4.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-trehalose-phosphate synthase"
                     /protein_id="HCR9916346.1"
                     /translation="MSRLVVVSNRIAPPDNKGGAGGLAVGVLGALKAAGGLWFGWSGE
                     TGNEDEPLKKVTKGNITWASFNLSEQDYEDYYCQFSNAVLWPAFHYRLDLVQFQRPAW
                     EGYMRVNALLADKLLPLIKENDIIWVHDYHLLPFASELRKRGVNNRIGFFLHIPFPTP
                     EIFNALPPHDELLEQLCDFDLLGFQTENDRLAFLDSLSSQTRVTTRSGKQHIAWGKDF
                     QTEVYPIGIEPDEIALQAAGPLPPKLAQLKAELKNVKNIFSVERLDYSKGLPERFLAY
                     EALLENYPQHRGKIRYTQIAPTSRGEVQAYQDIRHQLETEAGRINGKYGQLGWTPLYY
                     LNQHFDRKLLMKIFRYSDVGLVTPLRDGMNLVAKEFVAAQDPANPGVLVLSQFAGAAN
                     ELTSALIVNPYDRDDVAAALNRALTMPLAERISRHAEMLDVIVKNDINRWQERFIHDL
                     KEVTPRSPERQQQNNVATFPKLA"
     gene            complement(2007..2810)
                     /gene="otsB"
                     /locus_tag="OPV72_004200"
     CDS             complement(2007..2810)
                     /gene="otsB"
                     /locus_tag="OPV72_004200"
                     /EC_number="3.1.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose-phosphatase"
                     /protein_id="HCR9916347.1"
                     /translation="MAEPLTVSPELTANYAYFFDLDGTLAEIKPHPDQVVVPHKILQL
                     LDRLAAHNAGALALISGRSMTELDALAKPFRFPLAGVHGAERRDISGKTHIVRLPEAV
                     VREVEALLRSTLAALPGTELETKGMAFALHYRQAPEHEAALLALAQHVTQHWPQLALQ
                     PGKCVVEIKPKGTNKGEAIAAFMQEAPFTGRIPVFVGDDLTDEAGFGVVNHAGGISVK
                     VGVGATQAAWRLESVPDVWRWLEQINYPQQEQQVMNNRRDGYESFSRSI"
     gene            complement(3033..3209)
                     /gene="araH"
                     /locus_tag="OPV72_004201"
                     /pseudo
     CDS             complement(3033..3209)
                     /gene="araH"
                     /locus_tag="OPV72_004201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707790.1"
                     /note="Part of the ABC transporter complex AraFGH involved
                     in the high affinity transport of arabinose; incomplete;
                     partial in the middle of a contig; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose ABC transporter permease AraH"
     gene            complement(3444..4001)
                     /locus_tag="OPV72_004202"
     CDS             complement(3444..4001)
                     /locus_tag="OPV72_004202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HCR9916348.1"
                     /translation="MKKVAVLLAPGFEEAEAIVTLDILRRLHIDVETLACAESRAVVS
                     YHDIPMVADSTLSERQQALFDAVVLPGGPQGSANLAANPAVIAFVARHDAAGKLICPI
                     CSAAARVLGAHGLLKGRRYVCSGDLWKAVPEGVYVDAPVVEDGNLISGKGLGHVFDFA
                     LTLSARLLGDDALVREQAEHIYYPW"
BASE COUNT         1055 a         1148 c          970 g         1003 t
ORIGIN      
        1 ggtggtgtgt aaaaagtgtc ttatgccacg attctttaca taagaataat caatgattaa
       61 ttatgatgtc cttcacatta atgtggcatt agcgcattgc agaaatgcga taaacagagt
      121 aaagctaaag cacaatctca tattcttgca atcaaggagc gagttatgag ctacacccat
      181 attcttgtcg ccgttgccgt caccccggaa agtcaccagc tactggctaa agcggtctct
      241 atcgcccgcc ctgttcaggc gaaagtaagc ctgattactc tcgcttccga tcctgaactg
      301 tataaccagt tcgccgcgcc catgatggag gatttacgcg cggttatgca tgaagagacc
      361 gagaattttc ttaaaatgct gggggaaaag gcggattatc cgattgaaca aactttcatc
      421 gcatcaggtg agttaagcca gcatattttg gctgtgtgcc gcaaacacca tgttgatctg
      481 gtcatttgcg gcaaccataa ccacagtttc ttttcgcgcg cgtcctgctc ggcaaaagtg
      541 tcgtcagcgc cagccaggta gatgtgttgc tggtgccgtt agcgggcgac tagtcgccgc
      601 tcgcgatatc tcaggccagc ttagggaacg tcgccacgtt gttctgctgc tgacgctcag
      661 ggctacgcgg cgtgacctcc tttaggtcat gaataaaacg ctcctgccag cggttaatgt
      721 catttttaac gatcacgtcc agcatttccg catgacgcga aatacgctcg gcaaggggca
      781 tcgttaacgc acgattgagc gccgccgcca cgtcatcccg atcgtaagga ttgacgatta
      841 acgccgacgt cagttcattc gccgcgccgg caaactgtga cagtaccagt acgccaggat
      901 tagcggggtc ctgcgcggcg acaaactctt tcgccaccag gttcatcccg tcacgcaacg
      961 gggtgacgag cccgacgtct gaataacgga atatcttcat taacagttta cggtcgaaat
     1021 gctgattcag ataatagagc ggcgtccagc ccaattgtcc atatttccca ttaatccggc
     1081 ctgcttctgt ctcaagctgg tggcgaatat cctgatatgc ctgtacttcg ccgcgtgacg
     1141 taggcgcaat ttgggtataa cgaatttttc cccgatgctg cggatagttt tccagtagcg
     1201 cttcatacgc cagaaaacgt tccggcagcc ctttcgaata atccagccgc tcaacggaaa
     1261 aaatattctt cacatttttc agttccgcct tgagctgcgc cagttttggc ggcaacggcc
     1321 cggcagcctg cagagcaatc tcatcgggct caataccgat aggatacact tctgtctgga
     1381 agtctttacc ccacgcgata tgctgcttgc cgctgcgagt cgtgactcgc gtttgactcg
     1441 aaaggctatc cagaaaagcc aggcgatcat tttcggtctg gaacccgagc agatcaaagt
     1501 cacacaactg ctccagcagt tcatcatgtg gcggtaaagc gttaaaaatc tccggggtcg
     1561 ggaatggaat atgcaggaaa aaaccaattc ggttgttcac gccgcgttta cgcagctcgc
     1621 tggcaaacgg taacaggtgg tagtcatgca cccaaatgat gtcgttctct ttaatgaggg
     1681 gcaataactt atccgctaat aacgcattca cccgcatata gccttcccat gcaggacgct
     1741 gaaactgtac caggtccaga cgatagtgga acgctggcca gagaaccgca ttggaaaatt
     1801 gacagtaata atcttcgtaa tcttgttcac tcaggttaaa cgatgcccag gtaatattac
     1861 cttttgtcac cttttttaat ggctcatcct cgttacctgt ctcgccactc cagccgaacc
     1921 acaacccgcc agccgctttt agcgcgccaa gcacgccaac agcgaggccg ccggcgccgc
     1981 ctttattatc cgggggggca attcgattag atactacgac taaacgactc atagccatct
     2041 ctcctgttat tcattacttg ttgttcttgt tgtggataat tgatttgttc cagccagcgc
     2101 cagacatcgg gtacgctttc cagccgccat gccgcctggg ttgccccgac gcccactttt
     2161 acggaaattc cgccagcgtg attcaccacg ccaaagccag cctcatcggt caaatcgtcg
     2221 cccacaaaaa cgggaatccg tcccgtaaag ggcgcctcct gcataaaggc ggcaatcgct
     2281 tcgcctttat tagttccctt aggtttgatt tccacaacac atttaccagg ctgcaacgcc
     2341 agttgcggcc agtgctgcgt aacgtgttgc gcaagcgcca acagcgccgc ttcatgttcc
     2401 ggagcctgac ggtagtgcag cgcaaacgcc atcccctttg tctccagctc cgttccgggc
     2461 agcgctgcaa gcgtcgaacg taataacgcc tccacctcac ggactaccgc ttcaggaagg
     2521 cgcacgatat gggttttacc actgatgtca cgacgctctg ccccgtgaac gccagcgagc
     2581 ggaaagcgaa aaggcttcgc caaagcatcc agctcagtca ttgaacgccc tgaaatcaat
     2641 gccagtgccc ctgcgttgtg cgccgcgaga cggtctaaca actgaaggat tttatgcggt
     2701 accactacct gatcgggatg aggctttatc tctgccaatg tgccatcaag gtcaaaaaaa
     2761 tacgcatagt tcgcagtgag ttcgggggat acggttaacg gttctgccac cctggtctcc
     2821 tccttatcat catattgaga ctcacaaacg gtctcattag tcatgtaagt atagacagtg
     2881 tgacgctgct cgccatttag aaagaccatc gccagccggg gtagcggttg gcgatgacgt
     2941 gaagctatac tgtttagttg agtgttaatt catcaaatca tacgcttcgc tttttgctta
     3001 taatggtcga agataactgc tgccagaagg attcagccgc gaaccacgta ctgtgcaaaa
     3061 ggtgaaatgt tgagcaggtt catcgcgttc tccaccgttc ctgatatcag tacgctcgcc
     3121 accacatatg agatttttcc gaggccgcct ctcaggaaaa cgccccctaa tacgcacgca
     3181 gaaataacga ttaactcata acccagggaa ttcattgacc tgctttagcg ttttttatgt
     3241 agggtaaaat caaacgattc ttgttagaga agacgtaaaa cggtgcactg tctttcattc
     3301 attagataaa tgctgatggc tggaatagtt ttagcggaaa atgacataac ccagagcgaa
     3361 ttcatcagcc aaaaggcagg aaagccagca cattaatcca taacatcagc cagctaatcc
     3421 ttacggccct gggtgaataa cgattaccag ggataataga tatgttcagc ttgttcgcga
     3481 accagcgcat cgtctcccag cagtctggcg gaaagggtta gcgcgaaatc aaagacatga
     3541 cccaaccctt tgccgctaat taaattacca tcttcaacca cgggcgcatc cacatagaca
     3601 ccttccggaa ccgctttcca caggtcgccg gaacagacat aacgacgccc cttcagcaat
     3661 ccgtgagcac ccagcaccct tgccgccgcg gaacagatag gacaaattaa tttgcctgcc
     3721 gcatcatgac gcgcaacgaa agcgatcacc gccggattag ccgccagatt agcgctcccc
     3781 tgcggaccgc ccggcagcac taccgcatca aaaagcgcct gctggcgttc actcagcgtg
     3841 ctgtccgcaa ccataggaat atcatggtaa ctcaccaccg cccgtgattc agcacacgcc
     3901 agcgtttcga cgtcgatatg caaacgtcgc agaatatcaa gagtaacaat ggcctctgct
     3961 tcttcaaatc ctggcgccag tagcaccgcg acctttttca ttgactgctc cttgttaacg
     4021 agtcacccag caaaactgcg ctcaaccgaa taacgtgctc gtatgattaa tgatattaaa
     4081 aatgatctac cgcaaaatcg gctagtttat aaaaacaggc atatttgctc tcaaccgttt
     4141 atgcgtgtga tatccagact ggctaatgtt tatttt
//
LOCUS       DAJVBX010000266         4118 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.266, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000266 DAJVBX010000000
VERSION     DAJVBX010000266.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4118)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4118)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4118
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.266"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            3..785
                     /locus_tag="OPV72_004203"
                     /pseudo
     CDS             3..785
                     /locus_tag="OPV72_004203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460185.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
     gene            complement(891..1148)
                     /locus_tag="OPV72_004204"
     CDS             complement(891..1148)
                     /locus_tag="OPV72_004204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HCR9916349.1"
                     /translation="MKNVKNLIAAAVLSSLSFASFAAVEVQATPEGQQKFGTISANGG
                     TNLGSLEDQLAQKAQEMGAKSFRITSVTGPNTLHGTAVIYK"
     gene            1390..2025
                     /gene="comR"
                     /locus_tag="OPV72_004205"
     CDS             1390..2025
                     /gene="comR"
                     /locus_tag="OPV72_004205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family copper-responsive transcriptional
                     repressor ComR"
                     /protein_id="HCR9916350.1"
                     /translation="MTTDTTSCAKKSRGRPKVFDREAALDKAMTLFWQHGYEATSLAD
                     LVEATGAKAPTLYAEFTNKEGLFRAVLDRYITRFASKHEAQLFCEEKSVESALEDYFT
                     EIAACFTSTDTPAGCFMINTSATLAASSRDIARTVKSRHAMQEQTLIQFLRQHQERGE
                     IPAHCNPQALAEYINCILQGMSISAREGATFEQLMQITRTTLRIWPELLKS"
     gene            complement(2099..2638)
                     /locus_tag="OPV72_004206"
     CDS             complement(2099..2638)
                     /locus_tag="OPV72_004206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine zipper 2TM domain-containing protein"
                     /protein_id="HCR9916351.1"
                     /translation="MNKSMLAGIGIGVAAALGVAAVASLNVFDRGPQYAQVISAKPIK
                     ETVKTPRQECRNVTVTHRRPVQDENRIAGSVLGAVAGGVIGHQFGGGRGKDVATVVGA
                     LGGGYAGNQIQGSMQESDTYTTTQQRCKTVYDKSEKMLGYDVTYKIGDQQGKIRMDKD
                     PGTQIPLDGNGQLVLNNKA"
     gene            complement(2815..4062)
                     /gene="ndh"
                     /locus_tag="OPV72_004207"
     CDS             complement(2815..4062)
                     /gene="ndh"
                     /locus_tag="OPV72_004207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017373018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone dehydrogenase"
                     /protein_id="HCR9916352.1"
                     /translation="MATQLGHKLGRKKKAKITLVDRNHSHLWKPLLHEVATGSLDEGV
                     DALSYLAHARNHGFQFQLGSVMDIDREAKTITIAELRDEKGELLVPERKIAYDTLVMA
                     LGSTSNDFNTPGVKEHCIFLDNPHQARRFHQEMLNLFLKYSANLGANGKVNIAIVGGG
                     ATGVELSAELHNAVKQLHSYGYKGLTNDALNVTLVEAGERILPALPPRISSAAHNELT
                     KLGVRVLTQTMVTSADEGGLHTKEGEYIQADLMVWAAGIKAPDFMKEIGGLETNRINQ
                     LVVEPTLQTTRDPDIYAIGDCASCARPEGGFVPPRAQAAHQMATCAMNNILAQMNGKP
                     LKAYQYKDHGSLVSLSNFSTVGSLMGNLTRGSMMIEGRIARFVYISLYRMHQIALHGY
                     FKTGLMMLVGSINRVIRPRLKLH"
BASE COUNT          960 a         1152 c         1028 g          978 t
ORIGIN      
        1 taatgttcaa caatacgcga ctctctcgct ggtgggcgtt gcttgcgctt accgcgacca
       61 tcatgcttgc ccttcccgcg caggcgaata cgtggcctct tccgcccccc ggcagtcgac
      121 tggtgggaga aaataaattc catgtcgttg aagacgacgg cggctcgctg gaggcgatcg
      181 ccaaaaaata taacgtgggc tttttagccc tgttacaggc caaccccggc attgatcctt
      241 acgtgccacg cgcaggcagc gtgctgacga ttccgctgca aacgctgcta ccggacgcgc
      301 cacgtgaagg tatcgtcatt aacctcgctg aattacggct ttactattat caaccgggga
      361 aaaatacggt cacggtctac cctatcggca ttggccaact gggcggcgat accctgacgc
      421 caacgatggt gacgaccatt tcggataaac gcgccaatcc aacctggacg ccgaccacca
      481 atattcgcgc ccgttataaa gcgcaaggca tcgatctccc cgccgtggtg cctgccggtc
      541 ccgataaccc aatggggcat cacgcgattc gtttagcggc ctacggcggc gtctatctgt
      601 tacatggcac gaatgccggt tttggcattg gtatgcgcgt cagttccggc tgtatccgtc
      661 tgcgcgacgg tgatatagag acattgttcc gtcaagtcac gccgggaacc aaagtgaata
      721 ttatcaatac gccgattaaa gcctcggtgg agccaggcgg cgtgcgactg gtggaagttc
      781 atcagtcgct gtaagcgtga atagctgact gacaaaaaag cctcgcgatg catcgcgagg
      841 ctttctcttt ttattgtggc aatcgcagcg gcattaatga gggttaatgc ttacttatag
      901 attaccgccg taccgtggag ggtattcggg ccggtaacag aggtaatacg gaaagacttc
      961 gcccccattt cctgcgcttt ttgcgccagc tgatcttcca gcgagcccag attcgtgccg
     1021 ccattcgcgg aaatggtgcc gaacttctgt tgaccttctg gcgttgcctg aacttcaacg
     1081 gcggcgaagc tggcgaatga gagcgaactc agtaccgcag cagcgatgag gttttttacg
     1141 tttttcatag tgatgacctt tagcagatga atgggtgtcg caagcattaa cttaacgatc
     1201 gataaattaa tcatagatgt gatctacatc acacgtcaac ctctttttat aatgatcgtt
     1261 atataattta taaagatgtt atttttcatg tgaatagaat tgatttattt ttctaatgaa
     1321 tactctggag ccagaagtgg tttgttttta taatagagag accgctcttt aaacaggtac
     1381 aacggcatca tgacaacgga taccacgagt tgcgcgaaga aaagccgtgg ccgaccaaaa
     1441 gtgttcgaca gggaagccgc gcttgataag gccatgactc tcttctggca gcacggctat
     1501 gaagcaactt cgcttgccga tctcgtagag gctaccgggg cgaaagcgcc tactctctat
     1561 gcggaattca ctaacaaaga aggattattt cgcgctgtcc tggatcgcta catcactcgc
     1621 tttgcctcaa aacacgaagc ccagctcttt tgtgaagaga aaagcgtaga atcggcgctg
     1681 gaagattact tcacagaaat tgccgcctgc tttaccagta cagacacgcc ggctggctgc
     1741 tttatgatta atacgtccgc caccctggcc gcctcctcgc gcgatatcgc ccgcacggta
     1801 aaatcacgcc acgccatgca ggaacagacg ctcatccagt ttctgcgcca acatcaggag
     1861 cgcggtgaaa ttccggcgca ctgtaacccg caggcgctcg cggaatatat aaactgtatt
     1921 ttacagggaa tgtcgatcag cgcccgtgaa ggtgccacct tcgaacaact gatgcaaatt
     1981 acgcgtacga ctctgcgcat ctggcctgaa ctgctcaagt cctgaacgac gcggcttcgg
     2041 ataaaaaaag cccctcagcc tgagcgaatg aggggctaac ttgcagagta cagctttttt
     2101 atgctttgtt attcagaacc agttgaccat tgccgtcgag gggaatttgc gttccggggt
     2161 ctttatccat gcggattttg ccctgctgat cgccaatttt gtaggtcacg tcgtagccaa
     2221 gcatcttttc agatttgtca tacaccgtct tacagcgttg ctgcgtggta gtgtaggtat
     2281 cactctcctg cattgatccc tggatttgat tgccagcata accgccgccc agcgccccga
     2341 cgaccgtcgc cacatcttta ccacgaccgc cgccaaattg atgtccaatc acgccgcctg
     2401 ctactgcgcc aagcaccgag ccggcaatac ggttttcgtc ctgaaccggt ctacgatgcg
     2461 tgaccgtgac attacggcac tcctgacgcg gcgtttttac cgtctcttta atcggtttag
     2521 ccgatatcac ctgcgcatac tgcggaccac gatcaaatac gttgagactg gccactgccg
     2581 ccacacccag cgcagccgct acgccaatcc ctatacccgc caacattgat ttattcacgg
     2641 gagttcctcc ttcgttgcta ttggtaacaa ttttgcaacc agtatgcgaa caaagccaat
     2701 cggaatgagg atgaaaaatg cgggatgagg cggtaaagct gaaggattcg gacaactccg
     2761 aagcaagtga tggagaagcg ctcaccggcg agcagccggt gaggcgcaga aaaattaatg
     2821 cagtttcagg cgcggacgaa tgacgcggtt aatactgccc accagcatca tcaggccggt
     2881 tttaaagtat ccatgcagcg ctatctggtg catacggtat agcgagatat acacgaagcg
     2941 ggcgatacgt ccttcaatca tcattgaacc gcgggtcagg ttccccatca gactacccac
     3001 ggtagagaag ttggacagag agaccagcga tccatgatct ttatactggt aagctttcag
     3061 cggcttgcca ttcatctgcg ccagaatgtt attcatcgcg caggtagcca tctgatgcgc
     3121 cgcctgagcg cgaggcggca caaaacctcc ctccggacgt gcgcaggaag cgcagtcgcc
     3181 aatcgcataa atatcaggat cacgcgtggt ttgcagcgtc ggttccacca ccagttggtt
     3241 aatgcggttc gtttccagac caccaatttc tttcataaaa tctggcgctt tgatacccgc
     3301 cgcccacacc atcagatcgg cctgaatata ttcaccttct ttcgtatgca gaccgccttc
     3361 gtcggcgctg gtgaccatag tttgcgtcag tacgcgaacg cccagtttgg tcagttcatt
     3421 atgcgcggcg ctggagatac gcggcggcaa cgcaggcaga atacgctcgc cagcctcaac
     3481 caacgtcacg ttcaacgcgt cgttggtcag ccccttataa ccatagctat gcagctgttt
     3541 taccgcatta tgcagttcag ccgacagctc aacccccgtc gcaccgccgc caacgatggc
     3601 gatattgacc ttaccgttcg cgcccaggtt agccgaatac ttgaggaaca ggttcagcat
     3661 ctcctggtga aaacggcgcg cctgatgcgg gttatcgagg aagatacagt gctctttcac
     3721 gcccggcgtg ttgaaatcat tagaggtgct gcccagcgcc atcaccagcg tgtcatacgc
     3781 gattttgcgc tccggcacca gcagttcgcc cttttcatca cgcaactcgg caatggtgat
     3841 ggtcttcgct tcgcgatcga tatccatcac cgaccccagc tggaactgga aaccatgatt
     3901 acgcgcatga gccagatagc tcagcgcatc cacgccttcg tccagagagc cagtcgccac
     3961 ttcgtgcagc aatggtttcc acagatggct gtgatttctg tctaccagcg tgattttcgc
     4021 ttttttcttg cgccccagtt tatggcctaa ctgcgtcgcc atttccagcc cgccagcgcc
     4081 gccgccgaca atcacgatct tttttaatgg tgtagtca
//
LOCUS       DAJVBX010000267         4030 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.267, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000267 DAJVBX010000000
VERSION     DAJVBX010000267.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 4030)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4030)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4030
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.267"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..1689
                     /locus_tag="OPV72_004208"
     CDS             <1..1689
                     /locus_tag="OPV72_004208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aryl-sulfate sulfotransferase"
                     /protein_id="HCR9916353.1"
                     /translation="LPSPRESINQKIDTNNALVLNHNAIYEQRLAEITQSNTCDKAIV
                     TVNPYGTAPLSLYLGIWIDEAAALEINVVDSEATTEAVRYQYDVHPGANLIPVCGMVS
                     AVNNQITLRLASQIVGQYTVMTDALPPTDSANVSLGFPIISVSCPAQQASLMEEGLYF
                     STYFDRYNLAFDHNGIVRWYVSQEIPSYNFVRMDNGHFLATSQGINHCLNMYEFDIMG
                     RVYTVYLLDNEFHHSILPIENNLAIAPSEYSNGRPDGYSTGKDGVSIINLSTGLEVAY
                     YDMLYVMDYSRSPRPSGSAPGQDVSMDDWLHINQSYINEPNNLLICSGRHQSAIFGVN
                     VDSGELRFIMANHEDWSDEFKQYLLTPVDDDGVPLYDLTSPGGIDAADKNFWTWGQHN
                     IVEIPNDEPGILEFMVFDNGNYRSREDAKSLLPLDNFSRVVQFKINLNTMTVTRPYEY
                     GKTEVGNRGYSSFVSAKHLLTNGHLVIHFGATTVDEFEHTITAQPGSSDLVDPDEGQQ
                     ALGRLVLQEINKETKEVLFEAMVTSGYFKNEETNGTNYRYDISAFRVYKMPLFA"
     gene            complement(1735..3306)
                     /locus_tag="OPV72_004209"
     CDS             complement(1735..3306)
                     /locus_tag="OPV72_004209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HCR9916354.1"
                     /translation="MVYMNKKFSISLLSLCIGLSSAISFSADARDITIYYTNDLHAHV
                     TPEIIPYVSKTRPVGGFAPISKIVKDAKAKEKDVFFFDAGDYFTGPFISTLTKGEAII
                     DILNTMPYDAVSVGNHEFDHGHENLVKQLSKLQFPVLLDNVFYSGTDTPLIKEPYTIV
                     EKDGFKIGVIGMHGVSAFYEAIAAGVREGVDCRDPIPYVKKQLEELKGKVDLTVLLAH
                     EGVPGMQSSAGEADVARALKTDVDMAKSLEGYGLNVLITGHAHKGTPEPIKVGDTLVV
                     STDAYTIELGKLVLDWNPETKKVDSYNGKLITMYADTYKPDPVTQAKIDEWDNKVKKI
                     TDEVVAHSPEVLTRSYGESAPTGNLITDALMATVPGADASFYNAGGIRTELPKGNITY
                     GDVLSMYPFTNDVMSMEISGKDLKSIMSHAADLKNGMLHVSKTVQFKYDSTKPLGQRI
                     VEFDIKGKPVEDNKLYTVALDSFIGKGGGGFTFTKGKNIKYIGIQTAPALVNYMKQVN
                     NIQPDHTMRVDDISK"
     gene            complement(3405..4010)
                     /locus_tag="OPV72_004210"
     CDS             complement(3405..4010)
                     /locus_tag="OPV72_004210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001524208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916355.1"
                     /translation="MWKAVADFGAVFDRGEFASFYEMNVLNHPVEGRNHVTQFLGHYR
                     VVEGSNFTAMMKLYMSMENKFGDELNMMYGVGYLGLTSPSGFIKPYFAVHNLSNDYTS
                     KKYGQATGFNGYVLGWVAAYNFDMFNEKFVISNWNEVEMDRNDAYAEQQGGTTGLNGA
                     VTFTWKFMPRWTASVSYRYFNNKLGYNGYGDRMNYLIGFKF"
BASE COUNT         1058 a          918 c          930 g         1124 t
ORIGIN      
        1 ttgccctcac cgcgtgagtc gattaaccag aaaatcgata ccaataacgc attggtgtta
       61 aatcataacg ccatatatga acaacgatta gcggagatca cgcaatctaa tacctgtgac
      121 aaggccattg tcaccgtaaa tccctacggg accgccccgt tgagtctcta tctgggaatt
      181 tggattgatg aagctgccgc gcttgagatc aatgttgttg atagcgaagc gacgacagag
      241 gcagtgcgtt atcaatatga tgtacatccg ggcgctaacc ttattcctgt gtgtgggatg
      301 gtatccgcgg tgaataatca gattacccta cgccttgcct cgcaaattgt cgggcaatat
      361 acagtaatga ctgacgcatt accgcccacg gattcggcta acgtgagcct cggcttcccc
      421 attattagcg tctcctgtcc tgcgcagcag gcctcgctga tggaggaagg gctttatttc
      481 tctacttatt ttgatcggta taatctggct tttgatcata acgggattgt ccggtggtat
      541 gtaagtcagg aaatcccttc ttataatttt gtcagaatgg ataacggcca tttcctggcg
      601 acgtcacagg gaataaacca ttgtctgaat atgtatgaat ttgacattat gggacgggtt
      661 tatacggttt atcttctcga caatgagttc catcactcca ttcttcccat tgagaacaat
      721 ctggcgattg cgccttcaga atatagcaat ggacggccag atggttactc aaccgggaaa
      781 gatggcgttt ctattattaa cttatctacc ggacttgaag tcgcctatta cgatatgctg
      841 tatgtgatgg attattccag atcgccgcgt ccttccggaa gcgcgccagg tcaggacgta
      901 tcaatggatg actggctgca tatcaaccaa agctatatta atgaacccaa caatttgctg
      961 atctgttccg gtcgacatca gagcgcgatt tttggcgtaa atgtggattc cggcgaactg
     1021 cgctttatta tggcgaacca tgaggattgg tctgacgaat tcaagcaata cttattaact
     1081 cctgtcgatg atgatggcgt cccgctgtat gatcttacct cgccgggagg gattgatgcg
     1141 gcagataaga atttctggac ctgggggcag cataacattg ttgaaattcc aaatgatgag
     1201 cctggtattc tggagtttat ggtctttgat aatggtaact atcgttcacg cgaagatgcg
     1261 aaaagtttgt tgccgctcga taacttcagc cgggtggtgc agtttaaaat aaacctaaac
     1321 acgatgaccg taacgcgtcc gtatgaatat ggtaaaacgg aagtcgggaa ccggggctat
     1381 agcagttttg tgagcgctaa gcatttattg actaatggtc acctggttat tcacttcggc
     1441 gcgacgacgg ttgatgagtt tgaacatacc attaccgcgc aaccaggctc cagcgatctt
     1501 gtcgatccgg atgaagggca acaggcgtta ggtcgactgg tattacaaga aatcaataaa
     1561 gagacgaaag aggtcttatt cgaagcgatg gtgacgtcgg gctatttcaa gaacgaagag
     1621 acgaatggca cgaattatcg ttatgatatt tctgcatttc gggtatacaa aatgccgctg
     1681 tttgcataac taagtatgtt atgcggccgg ttatcgaccg cataacatta tggcttattt
     1741 gctaatatca tccacgcgca tggtgtggtc aggttgaata ttgttaacct gcttcatata
     1801 gttaaccaac gccggtgcgg tttgtatccc tatatatttg atatttttac ctttagtgaa
     1861 ggtaaatccg ccaccacctt taccgataaa ggaatccagc gcgacggtat agagtttatt
     1921 gtcttctacc ggtttgcctt tgatatcaaa ttcaacaata cgctggccca gcggtttggt
     1981 actgtcatat ttaaactgga cggttttaga tacgtgcagc ataccgtttt tcagatcggc
     2041 agcgtgtgac atgatggatt tcaggtcctt accgctgatt tccatgctca tgacatcgtt
     2101 ggtgaacgga tacatactca gcacatcacc ataggtgata ttacctttag gcaattcggt
     2161 acggatgccg ccagcattat agaaggaagc gtcggcgcca ggaacggtag ccatcagggc
     2221 atcggtgatt aagttgccgg ttggcgcgga ttcaccgtaa gaacgggtca gcacttccgg
     2281 agagtgcgcg accacttcat cggtaatttt cttaaccttg ttatcccatt cgtcaatttt
     2341 ggcctgcgtg accggatctg gcttataagt atccgcatac atggtgatca acttaccatt
     2401 gtagctgtcc acttttttgg tttccgggtt ccagtcaagc accagtttac ctaattcgat
     2461 ggtgtacgca tccgtggaaa cgacaagagt atcgcccact ttaatcggtt ctggcgtacc
     2521 tttatgcgca tggccggtaa tcaggacgtt aagtccatag ccttccagcg atttcgccat
     2581 atcaacgtcg gttttcagtg cgcgtgcgac atcagcctcg cccgcgctgg actgcatacc
     2641 cggcacgcct tcgtgggcga gcagcacggt caggtcaact ttccctttta actcttccag
     2701 ctgttttttc acataaggaa tcggatcgcg gcagtcaacg ccttcacgca cgcctgcggc
     2761 aatcgcttca tagaatgcgg aaacgccgtg cataccgatg acgccgatct tgaatccatc
     2821 tttttccaca atggtatacg gttctttaat taatggcgta tctgtgccgc tgtaaaaaac
     2881 attatccaac aataccggga attgcaattt gctgagctgt ttaaccagat tctcatggcc
     2941 atggtcaaat tcatggttac cgacagagac ggcgtcgtaa ggcatggtat ttaaaatatc
     3001 aataatagcc tcgcctttgg tcagcgtact gataaaaggt ccggtgaaat agtcgccagc
     3061 atcaaagaaa aagacatctt tctctttcgc ttttgcatct ttgacaattt tcgagatggg
     3121 cgcaaagccg cctaccggac gtgtcttgga tacatagggg ataatttctg gggttacatg
     3181 ggcatgtaaa tcgttcgtat aataaattgt gatgtcacgc gcatcggctg aaaaggaaat
     3241 ggctgaagac aaaccaatgc acagcgacag tagggatatc gaaaactttt tgttcatata
     3301 aaccatccat ttacgctaca ttaaagaaaa acaatgcctg tagtcgtgtc attcacgact
     3361 acaaaccggg gaaattaagt aatattcatc aagtttatta attattaaaa cttgaagccg
     3421 atcaggtaat tcatacggtc gccgtagccg ttatacccca atttattatt gaagtaacgg
     3481 taagagacgg aggcggtcca tcgcggcata aatttccatg taaacgttac cgcgccgttc
     3541 aggccggtcg tcccaccctg ttgttcggcg taggcatcat tacgatccat ttcaacttcg
     3601 ttccagtttg aaatgacgaa cttttcatta aacatatcga agttataagc cgcgacccaa
     3661 ccgagaacat aaccgttaaa gcctgtcgcc tgtccatact ttttagaggt ataatcgttc
     3721 gataagttat gaacagcgaa atagggctta ataaagcctg atgggctggt taaacccaga
     3781 taacctaccc cgtacatcat gtttaattca tcaccgaatt tattctccat cgacatatag
     3841 agtttcatca ttgcggtaaa gttagagcct tctactaccc tataatgtcc cagaaattgg
     3901 gtaacatggt tacggccttc taccggatgg ttgagcacgt tcatttcata aaatgatgca
     3961 aattcgcccc tgtcaaacac ggcgccgaaa tcggctaccg ctttccacac ttcgccgcga
     4021 tcgacattga
//
LOCUS       DAJVBX010000268         3980 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.268, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000268 DAJVBX010000000
VERSION     DAJVBX010000268.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3980
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.268"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            78..554
                     /locus_tag="OPV72_004211"
     CDS             78..554
                     /locus_tag="OPV72_004211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916356.1"
                     /translation="MSKDEISYQILYRYSLEKLYSTLTRRVDNVLSFALVFLGVGVTI
                     NVGSPFILGPGIVGIAILKRVLRFGTRSTQADRQSRAWLKLFNTQHRFPSDKTLFLAF
                     TSLEQDASEVWSMLIGPAIVMTETALGKTPIEPLTAGEKLCAFLSGATKSQPAARN"
     gene            complement(942..1361)
                     /locus_tag="OPV72_004212"
     CDS             complement(942..1361)
                     /locus_tag="OPV72_004212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCR9916357.1"
                     /translation="MDIQITHQVTEFDKEELLAGLRSYNAQFVDFSKNGQLGVYCRNE
                     SGEMVGGLIADRKGPWLCIDYLWVSESARSRGLGSQLMEMAEKEGLRKGCVHGLVDTF
                     SFQALPFYEKQGHILQMSLPDFPKVGSQRHYLIKPDL"
     gene            1732..1998
                     /locus_tag="OPV72_004213"
     CDS             1732..1998
                     /locus_tag="OPV72_004213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916358.1"
                     /translation="MKFDNAWNQGVWYALRSATGRLSPQPFSVEDLPALGEECRRIMK
                     ITSAVYTSKKTLSERWFASAELLNLYLTKYGLSCLNCSRKKTTA"
     gene            2167..2307
                     /locus_tag="OPV72_004214"
     CDS             2167..2307
                     /locus_tag="OPV72_004214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460815.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916359.1"
                     /translation="MFRSTRTLPRNLQTYTEQASTEELHTDLNNMQSTGLYSIQQMVL
                     QL"
     gene            complement(2349..3553)
                     /locus_tag="OPV72_004215"
                     /pseudo
     CDS             complement(2349..3553)
                     /locus_tag="OPV72_004215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343613.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
BASE COUNT         1038 a          979 c          908 g         1055 t
ORIGIN      
        1 aagtgtggca taattgcaga atctgtcagg attccgggag cataccggag cgtaatcgaa
       61 aaaccatctg gagatgtatg agcaaagatg aaatcagtta tcaaattctt taccggtact
      121 ctctggaaaa actatacagt actcttacca gaagagtaga taacgtgctg tcattcgccc
      181 tcgtttttct cggggtcggc gtcaccataa acgtcgggag tccctttatt ctggggccag
      241 gcattgtggg tatcgccata ctaaaaagag tactccgctt cggcacgcgc tcaacacagg
      301 ccgaccggca gtcccgcgcc tggctgaaac tttttaatac tcagcaccgc tttccttcag
      361 ataagacact gttccttgcc ttcacatcgc ttgagcaaga cgcgagcgaa gtatggtcca
      421 tgcttattgg tcctgccatc gtcatgactg agaccgccct cggaaaaacg cccattgagc
      481 cattgacggc gggtgaaaaa ctctgtgcat ttttgagtgg cgcgacgaaa tcccagccag
      541 cagctcgcaa ttgacctgtc ttctaaacgt ctgtgccata ccacagagat ttagtacaaa
      601 attaattaat ggagcactaa cgctgtcagc aggtttctct gagtgaaaga ttcgtattat
      661 acgcacagcc cagtttacag tttatataac agcgctatat gtttttgtat ccgtaccatg
      721 ccgcctacaa gcggctgtct gagtacctct agccgtgcca gggggtatta gctcaaatgt
      781 gagctgacat atctatggca cagcgccaaa cctaatctga ctgtccgccc tgcgccagaa
      841 gcggacgctg aacatggtgt gtacaggcca acaatacgat atattttaaa gctacctgat
      901 tgcagctttc ataaggctat gggtattcaa atgtagcaaa gctataaatc aggcttaatt
      961 aaataatgcc tttgcgaacc tactttagga aagtccggta gcgacatttg aagtatatga
     1021 ccctgttttt cataaaaagg gagagcctgg aagctaaagg tatctacaag tccatgaaca
     1081 cagcctttcc gcaaaccttc tttttcggcc atctccataa gttgactccc cagaccgcgg
     1141 ctccttgcag attcacttac ccaaagatag tcgatgcaaa gccacggacc ttttctgtca
     1201 gcaattaatc cgcctaccat ttcgccgctt tcgtttctgc agtagacccc aagctgccca
     1261 tttttactaa aatcgacgaa ctgagcattg tagcttctta atccggctaa tagttcttct
     1321 ttatcaaatt cagtaacttg atgtgtaatt tgaatgtcca tacatatcca attgaacaag
     1381 tttgcatttg gaatataacg ttataaataa gttaattaaa tgtatcaata gaaagtttat
     1441 ttttactcct gcggggcagg tcacgtccgc tactcgctta aagcaaactg tcagttggag
     1501 tctgagctgg tacaattaat gtgccactgg ttagaaatca gtaatacgat tttatcaggc
     1561 tgatactctg gcctgtcagg atttgaggta tccacccggt ttaccagccc actgtatttg
     1621 gcaccagtgg aacccacttc ccgatccagg atatccagta tccaccgccg aacctctttc
     1681 cccaaaagat atgtgcaacc tcaagcgcct tgtctggatg atgaccacgg tatgaagttt
     1741 gataacgcgt ggaatcaggg cgtttggtac gctctccgtt cagcaactgg acgcctttct
     1801 ccccagcctt tcagcgttga agatttgcca gcgctgggtg aagagtgtag gcgaattatg
     1861 aaaatcactt ctgccgttta tacttcgaaa aagacgttat cagaaaggtg gttcgcaagc
     1921 gcggagttat taaaccttta cttaacgaaa tacggtttaa gttgcttgaa ttgcagcaga
     1981 aagaaaacga cggcttgatg atgctggaca aattaagcga gcatggcatc aatggactga
     2041 tacgccgtca ataaaaggaa gggtgcatgg acgatcccgt cacatcacca atcacaacag
     2101 aagagcacaa aacaacattt cacagcgtaa atgataaaac acgatgccat tttcaatcaa
     2161 aaacatatgt tcaggtccac aaggacacta cccagaaatc tccagaccta tacagaacaa
     2221 gccagtaccg aggaattgca cactgatctc aacaacatgc aaagtactgg actatacagt
     2281 attcagcaaa tggtcctgca gttatgaaat gcgcccaccc ggtgcagaag aaagaacctc
     2341 acgactaaaa ttatcagcat caggcggtca ccgaacccga taataaaacg gctcatcgcc
     2401 agccaccagc tctggagcgg tatactccat tttttgacgc atccttgatc gccagataaa
     2461 taacttttcg tactgagtca tccgtcggga acaccttgca tttctttatc gcggcacgga
     2521 tcacgctgtt cagggattcg actgcgtttg tcgtgtagat ggccttgcgg atatccggcg
     2581 gataactgaa gagcgtattg aggttttccc ggtgcgcacg ccagcttttg ctgatttgcg
     2641 gatatttatc gtcccggact ttcgcgaacg catctatcgc catcagtacc gcatcttcgg
     2701 tcggggcctg atagaccatc ttccggccgc tggtgacggc tttgtagtct ttccaggcta
     2761 cgtatttcag gctgttacgc atcatatgga tactgcacag ctgaatatgg gtttgcggga
     2821 agacgctatt tatcgcatcc gggaagccct tcagaccatc cacacaggca atcaggatgt
     2881 cctgaaggcc ccgggttttc agctccgtca gcacgcttag ccagaacttt tcgcattcat
     2941 tttcggccag ccacataccc agtaactctt tctggcgttc ggtgttgata cccagtgcca
     3001 ggaagacggc tttgttgatt acgctgccat tctgacggac tttgacgaca acgcagtcca
     3061 tataaacaat ggggtacagc gcatccagtt gccggttttg cctctcagtg acctgctctt
     3121 ttacggcgtc ggtgacttta gatatcagcg aaggtgacac atcggcgtcg tacatctctt
     3181 tggaggtggc gacgatttcg cgggtagtca tgcctttggc gtagagggat aaaatttggc
     3241 tgtccatctg cgtaatgcgc gtctggtgct tcttaagtag ctgcggttcg aaggtgtttt
     3301 cacggtcacg cggcgtgttc agttcgatct cgccgtcatc gcataacacc gtttttgacg
     3361 agtagccatt gcgggtgttt gagcctgttt tgggggcgtt tttctcatac ccggggtggt
     3421 cagtcagcta cgcattgagc gccgtttcga cggttaattt cgtcagcata cgggaaaacg
     3481 gattgaggtc ggcttcggtt ttaaggcctt tagccagttc agccgcaagg aatttgagtt
     3541 tcttttcgtc cataattgcc tgtctccgtt actggagtga acatatcaaa aacaggcaat
     3601 tacacaattt taattacagt ctcagttcag tcacattatt gatgagcgac tgtacgttaa
     3661 gccaatcaag accgagatga aaatcgctct gccactttcg ctcacccctc cttccatggg
     3721 tttacgcctc agtacggtga ttgatcgttg ccgcctggta agccgtagcg aataccttat
     3781 cagcgctggc atacgcaaaa accgcccgaa cgggagtatt catcctgaca gcctgactaa
     3841 aaaatttgtt gcggcacgaa aatttaccgg aataaattta gtgataaccc accgacattt
     3901 cacgagatcc gcagcttatc cggacgacta tataaagatg cttacgggga agggtttgct
     3961 cagaaactcc tgggacatac
//
LOCUS       DAJVBX010000269         3978 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.269, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000269 DAJVBX010000000
VERSION     DAJVBX010000269.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3978)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3978)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3978
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.269"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..145)
                     /locus_tag="OPV72_004216"
     CDS             complement(<1..145)
                     /locus_tag="OPV72_004216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2574 family protein"
                     /protein_id="HCR9916360.1"
                     /translation="MKKYLLMGIIVSAYGISVPVFASDTATLTISGKVTAPTCSTEVV
                     NAQL"
     gene            complement(423..1532)
                     /gene="apbC"
                     /locus_tag="OPV72_004217"
     CDS             complement(423..1532)
                     /gene="apbC"
                     /locus_tag="OPV72_004217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster carrier protein ApbC"
                     /protein_id="HCR9916361.1"
                     /translation="MNEQSQAKSPDTLRAMVAGTLANFQHPTLKHNLTTLKALHHVAW
                     MDDTLHVELVMPFVWNSAFEVLKEQCSADLLRITGAKAIDWKLSYNIATLKRVKNQPG
                     INGVKNIIAVSSGKGGVGKSSTAVNLALALEAEGAKVGVLDADIYGPSIPTMLGAEDQ
                     RPTSPDGTHMAPIMSHGLATNSIGYLVTDDNAMVWRGPMASKALMQMLQETLWPDLDY
                     LVLDMPPGTGDIQLTLAQNIPVTGAVVVTTPQDIALIDAKKGIVMFEKVEVPVLGIVE
                     NMSMHICSNCGHHEPIFGTGGAQKLAEKYHTQLLGQMPLHISLREDLDRGTPTVVSRP
                     ESEFTAIYRELADRVAAQLYWQGEVIPGEIAFRAV"
     gene            1697..3730
                     /gene="metG"
                     /locus_tag="OPV72_004218"
     CDS             1697..3730
                     /gene="metG"
                     /locus_tag="OPV72_004218"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HCR9916362.1"
                     /translation="MTQVAKKILVTCALPYANGSIHLGHMLEHIQADVWVRYQRMRGH
                     EVNFICADDAHGTPIMLKAQQLGITPEQMIGEMSQEHQTDFAGFNISYDNYHSTHSDE
                     NRELSELIYTRLKENGFIKNRTISQLYDPEKGMFLPDRFVKGTCPKCKSADQYGDNCE
                     VCGATYSPTELIEPKSVVSGATPVMRDSEHFFFDLPSFSEMLQAWTRSGALQEQVANK
                     MQEWFESGLQQWDISRDAPYFGFEIPNAPGKYFYVWLDAPIGYMGSFKNLCDKRGDTT
                     SFDEYWKKDSDAELYHFIGKDIVYFHSLFWPAMLEGSHFRKPTNLFVHGYVTVNGAKM
                     SKSRGTFIKASTWLKHFDADSLRYYYTAKLSSRIDDIDLNLEDFVQRVNADIVNKVVN
                     LASRNAGFINKRFDGVLAAELADPQLYKTFTDAAAVIGEAWESREFGKAIREIMALAD
                     VANRYVDEQAPWVVAKQEGRDADLQAICSMGINLFRVLMTYLKPVLPTLSERVEAFLN
                     SELNWDAIEQPLLSHKVNTFKALYNRIDMKQVEALVEASKEEVKAAAAPVTGPLADFP
                     IQETITFDDFAKIDLRVALIENAEFVDGSDKLLRLTLDLGGEKRNVFSGIRSAYPDPQ
                     ALIGRQTVMVANLAPRKMRFGVSEGMVMAAGPGGKDIFLLSPDDGAKPGQQVK"
BASE COUNT          962 a         1066 c          987 g          963 t
ORIGIN      
        1 gcaactgtgc gtttaccact tctgtactgc acgttggcgc ggtcactttt ccactgatgg
       61 ttaatgttgc ggtgtcggag gcaaaaacag gtacgcttat cccataagcc gaaactataa
      121 ttcccatcag caaatatttt ttcatagtga gtaattgttc ctctggtgaa cgtcaaacag
      181 tatgcaggcc gtcctgatga gcagtatgaa cgtatcgata ccttaaaacc aattgaaaaa
      241 ataaatcagt aggataggta tgatcaattc aaataatgtt tttgccgatt atttcagata
      301 aacacctgtc tgtttaagca ggaattaaca atgcgggggc tattatttta ttaatacatt
      361 cactgcatca atatatatta atgcagtgaa tgtcatattc tctttggaat acgtcaggag
      421 gattacaccg cgcggaaggc gatttctccc ggaatcactt caccctgcca gtaaagctgt
      481 gccgcaacgc gatcggccag ttcgcgatag atcgcggtaa actcgctctc cggacggcta
      541 accaccgtcg gcgtaccgcg atcgagatct tcacgcagac taatatgcag cggcatctga
      601 cccagaagct gagtatggta tttttccgcc agcttctgcg cgccgcccgt gccgaagatc
      661 ggttcgtgat ggccgcagtt gctacaaata tgcatactca tattttccac aatgccgagc
      721 accggcactt ccaccttctc gaacatcacg ataccttttt tggcgtcgat tagcgcgata
      781 tcctgcggcg tagtcaccac caccgcgccg gtaacaggaa tgttctgcgc cagcgttagc
      841 tgaatatccc cggttcccgg cggcatatcc agtaccagat aatccagatc cggccacagc
      901 gtctcctgca acatctgcat cagcgcctta ctggccattg ggccgcgcca taccatcgcg
      961 ttatcgtcag tcaccagata gccgatcgag ttggtcgcca ggccgtgaga cataatcggc
     1021 gccatatgcg taccgtctgg cgatgtcggg cgctgatctt ctgcgccaag catggttggg
     1081 atcgacggac cgtaaatatc ggcatcgaga accccgacct ttgcgccttc agcctctaac
     1141 gccagcgcca ggtttaccgc cgtggacgat ttacccaccc cgcctttacc ggagctcacg
     1201 gcaatgatgt ttttcacgcc attaatgcca ggctgatttt tgacgcgttt cagcgtcgca
     1261 atgttgtacg acagtttcca gtcgatcgct tttgcgcccg taatacgtaa cagatcggcg
     1321 ctgcattgct cttttaatac ctcaaacgcg ctgttccaga cgaacggcat gaccagctca
     1381 acgtgcagcg tatcatccat ccaggcgacg tggtgcaacg ccttaagcgt ggtgaggtta
     1441 tgcttcaggg ttgggtgctg aaaattcgcc agcgtcccgg cgaccatcgc tcgcagggta
     1501 tctggtgatt tggcctggga ttgttcgttc atcccgactc cttttgtagt tctgaaaagt
     1561 acgattgtaa ctttgtagtt tactccagcg gtaacaatta ttcatttacg gataaatgcc
     1621 cttatcgatt ggcgcagtaa ttaccatttt ggtactatca aagccctttt ttacaacaga
     1681 agaagtaata cccactatga ctcaagtcgc gaagaaaatt ctggtaacgt gcgcgctgcc
     1741 gtacgccaac ggctctatcc acctcggcca tatgctggag cacatccagg ctgatgtctg
     1801 ggtccgttac cagcgaatgc gcggccatga ggttaacttc atctgtgccg atgacgctca
     1861 tggcacgccg atcatgctga aagcgcagca gcttggtatt acaccggagc aaatgatcgg
     1921 tgaaatgagc caggagcacc agaccgattt cgccggtttt aatattagct acgacaacta
     1981 ccactcaacg cacagcgacg agaatcgcga gctgtccgag ctgatttata cgcgcctgaa
     2041 agagaacggt tttattaaga accgcaccat ctctcaactc tacgatccgg aaaaaggcat
     2101 gttcctgccg gatcgatttg tgaaaggcac ctgcccgaaa tgtaaatccg cggaccagta
     2161 cggcgataac tgtgaagtct gcggcgcaac ttacagcccg accgaactta tcgagccgaa
     2221 atccgtggtg tccggcgcga cgccggtaat gcgtgactcc gagcactttt tctttgacct
     2281 gccgtcattc agcgaaatgt tgcaggcgtg gacccgcagc ggcgcgctgc aggagcaggt
     2341 ggcgaacaaa atgcaggagt ggtttgaatc cggcctccag cagtgggaca tttcccgcga
     2401 cgcgccgtat tttggtttcg aaatcccgaa cgcgccgggc aaatatttct acgtctggct
     2461 ggacgcgccg attggctata tgggctcctt caaaaatctg tgcgataagc gcggtgacac
     2521 gaccagtttt gatgagtact ggaaaaaaga ctccgacgcc gagctgtatc actttatcgg
     2581 caaagacatc gtctatttcc acagcctgtt ctggcctgcc atgctggaag gcagccactt
     2641 ccgtaagccg accaacctgt tcgttcacgg ttacgtgacg gtgaacggcg cgaagatgtc
     2701 taagtctcgc ggcaccttta ttaaggccag cacctggctg aaacactttg acgccgacag
     2761 cctgcgctac tactacaccg cgaagctttc ttcacgcatt gatgacatcg acctgaacct
     2821 ggaagacttt gtccagcgcg tcaatgccga tatcgtcaat aaagtagtca acctggcatc
     2881 ccgtaacgcc ggttttatca ataagcgttt cgacggcgtg ctggcggctg aactggccga
     2941 tccgcaattg tacaaaacct ttactgacgc cgctgcggtg attggcgaag catgggaaag
     3001 ccgtgaattc ggtaaagcta tccgtgagat tatggcgctg gccgacgtcg ctaaccgtta
     3061 tgttgacgag caagcgccgt gggtggtggc taaacaggaa ggccgcgacg ctgacctgca
     3121 ggccatttgc tcgatgggca tcaacctgtt ccgcgtgctg atgacgtatc tgaaaccggt
     3181 actgccgacg ctttctgaac gcgttgaagc cttcctgaac agcgaactga actgggatgc
     3241 catcgaacag ccgctgctca gtcacaaggt caacaccttt aaggcgctct acaatcgcat
     3301 cgacatgaag caagttgaag cgctggttga agcgtctaaa gaagaggtga aagccgcagc
     3361 cgcgccggtt accggcccgt tagccgactt cccgattcag gaaaccatca cctttgacga
     3421 tttcgccaaa attgacctgc gcgtagcatt gattgaaaac gctgagttcg tagatggttc
     3481 tgacaaattg ctgcgtctga cgctggatct gggcggcgag aagcgtaacg tcttctccgg
     3541 cattcgttcc gcctacccgg acccgcaggc gctgatcggc cgccagacgg taatggtcgc
     3601 caacctcgcg ccgcgcaaaa tgcgctttgg cgtctccgag ggaatggtga tggccgcagg
     3661 acctggcggg aaagatatct tcctgttaag ccctgatgac ggcgcgaagc ctggccaaca
     3721 ggtgaaataa gcaacaagcc ggagcatgct ccggcttttt taaccgctta atcctgactg
     3781 gcatatcacc ccatccgcgt gttttaactt tttccttaat aagcaatagc gttaagactc
     3841 catatccgga ctgctaaata acggctaaaa gtcatattct atctctccct gatacattgc
     3901 tattactggg ttaaattaat tcattgaaat tattttaaaa acccaatcat tatataaaat
     3961 ggagttttag atgaaaat
//
LOCUS       DAJVBX010000270         3948 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.270, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000270 DAJVBX010000000
VERSION     DAJVBX010000270.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3948
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.270"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(257..727)
                     /locus_tag="OPV72_004219"
     CDS             complement(257..727)
                     /locus_tag="OPV72_004219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilin structural protein SafD"
                     /protein_id="HCR9916363.1"
                     /translation="MWMKIQRVKTVIYSVSLLVAASSLVPIANAAEKLQTTLRVGTYF
                     RAGHVPDGMVLAQGWVTYHGSHSGFRVWSDEQKAGNTPTVLLLSGQQDPRHHIQVRLE
                     GEGWQPDTVSGRGAILRTAADNASFSVVVDGNQEVPADTWTLDFKACALAQEDT"
     gene            complement(749..3259)
                     /locus_tag="OPV72_004220"
     CDS             complement(749..3259)
                     /locus_tag="OPV72_004220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HCR9916364.1"
                     /translation="MKFKQPALLLFIAGVVHCANAHTYTFDASMLGDAAKGVDMSLFN
                     QGVQQPGTYRVDVMVNGKRVDTRDVVFKLEKDGQGTPFLASCLTVSQLSRYGVKTEDY
                     PQLWKAAKTPDECADLTAIPQAKAVLDINNQQLQLSIPQLALRPEFKGIAPEDLWDDG
                     IPAFLMNYSARTTQTDYKMDMVGRDNSSWVQLQPGINIGAWRVRNATSWQRSSQLSGK
                     WQAAYTYAERGLYSLKSRLTLGQKTSQGEIFDSVPFTGVMLASDDNMVPYSERQFAPV
                     VRGIARTQARVEVKQNGYTIYNTTVAPGPFALRDLSVTDSSGDLHVTVWEADGSTQMF
                     VVPYQTPAIALHQGYLKYSLLAGRYRSSDSATDKAQIAQATLMYGLPWNLTAYGGIQS
                     ATHYQAASLGLGGSLGRWGSLSVDGSDTHSQRQGEAVQQGASWRLRYSNQLTATGTNL
                     FLTRWQYASQGYNTLSDVLDSYRHNGNRLWSWRENLQPSSRTTLMLSQSWGRHLGNLS
                     LIGSRTDWRNRPGHDDSYGLSWGTSIGGGSLSLNWNQNRTLWRNGGHRKENITSLWFS
                     MPLSRWTGNNVSASWQMTSPSHGGQTQQVGVNGEAFSQQLDWEVRQSYRADAPPGGGN
                     NSALHLAWNGAYGLLGGDYSYSRAMRQMGVNIAGGIVIHHHGVTLGQPLQGSVALVEA
                     PGASGVPVGPWPGVKTDFRGDTTVGNLSVYQENTVSLDPSQLPDDAEVTQTDVRVVPT
                     EGAVVEAKFHTRIGARALMTLKREDGSAIPFGAQVIVNGQDGSADLVDTDSQVYLTGL
                     ADKGELTVKWGAQQCRVNYHLPAHKGIAGLYQMSGLCR"
     gene            complement(3283..>3948)
                     /gene="papD"
                     /locus_tag="OPV72_004221"
     CDS             complement(3283..>3948)
                     /gene="papD"
                     /locus_tag="OPV72_004221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pili assembly chaperone PapD"
                     /protein_id="HCR9916365.1"
                     /translation="AEQKLSLNTKSFSVKLGATRVIYHAGTVGATLSVSNPQNYPILV
                     QSSVKAADKSSPAPFLVMPPLFRLEANQQSQLRIVRTGGDMPTDRETLQWVCVKAVPP
                     ENEPSDTQAKGATLDLNLSINVCDKLIFRPDAVKGTPEDVAGNLRWVEAGNKLKVENP
                     TPFYMNLASVTVGGKPITGLEYIPPFADKTLNMPGSAHGDVEWRVITDFGGESHPFHY
                     VLK"
BASE COUNT          922 a         1175 c          882 g          969 t
ORIGIN      
        1 agagtgaatc aaacaaatcc acaaaacaga aaataataaa ggcatcagtg tccgttaaat
       61 tattttacga aacataatat tcctctccct acaaaaaaag atgaatttca gattttaaaa
      121 tcaatcagca attgattttt ctgcaatgaa gattgctaac catatttgcc ttgagtaaat
      181 tttcaataca tcctcgaacc tgatatacag tattcgcctt attcactgat acaggaagta
      241 tgagtggaac agacggctac gtatcctcct gcgccaatgc acaggcctta aaatccagcg
      301 tccaggtgtc cgcaggcact tcctgattgc catcaacgac cacactgaaa ctggcgttat
      361 ctgcagcggt tcttaaaatg gcgccacgac cactcaccgt atctggttgc cacccctcgc
      421 cctccaggcg aacctgaatg tgatggcgag gatcctgttg cccgctcagc agcaatacgg
      481 taggcgtgtt acccgccttt tgctcatcgc tccatacccg aaacccgctg tgactgccgt
      541 gataagtcac ccagccttgc gcaagcacca tcccatctgg cacatgcccg gcccgaaagt
      601 aagtacctac acgtagcgtt gtctgaagtt tttctgcggc gttcgctatc ggcaccaagc
      661 tactggcagc gaccagtaag cttacgctat agataaccgt tttcactcgc tgtattttca
      721 tccacattat tctctccttc agaatcggct atctgcagag accgctcatt tgatacaagc
      781 ccgcgattcc cttgtgggca ggtaggtggt agttaacccg acattgctgt gctccccatt
      841 tcaccgtcag ttcgccctta tccgccagac cagtgagata aacctggcta tcagtatcca
      901 ccagatcagc gctgccatcc tgcccattga ctataacctg cgccccgaaa ggaatggcgc
      961 taccatcttc ccgtttcagc gtcatcagtg ccctggcccc gatgcgagtg tgaaacttcg
     1021 cttccaccac cgccccttcg gttggcacca cgcgcacatc ggtttgtgtg acctctgcgt
     1081 catccggtag ttgcgacgga tcgaggctga ctgtattctc ctgatagacg ctcaggttgc
     1141 ccactgtggt gtcgccacga aaatccgtct taacgccagg ccaggggcca actggcaccc
     1201 ccgaggcccc tggcgcttca accagcgcca ctgagccttg caaaggttgc cccagcgtca
     1261 caccatgatg gtggataact atacctcccg cgatattgac tcccatctgg cgcatcgccc
     1321 ggctgtagct atagtcacca cctaacaggc cgtaagcccc attccatgcc aagtgcaatg
     1381 cgctgttatt accaccacct ggcggggcat cggcacggta actctgacgc acctcccaat
     1441 ccagttgctg actgaatgcc tctccgttga cccccacttg ttgcgtctga ccaccgtgtg
     1501 atggtgaagt catctgccaa ctagcactta cattattccc cgtccagcgg cttaatggca
     1561 tactgaacca caggctggtt atgttctctt tacggtgccc gccattgcgc cacagcgttc
     1621 tgttttgatt ccagttcaat gacagcgagc cccctccgat agaggttccc caactcagtc
     1681 cgtagctgtc atcatgaccg gggcgattac gccagtcggt acgggaaccg attaaactca
     1741 gattgcccaa atgcctcccc catgactgac tcaacatcag ggtggtacgt gagctcggct
     1801 gcaaattttc ccgccacgac catagacggt tgccattatg tcgataactg tcgagcacat
     1861 cggatagggt gttatagccc tgcgaggcat attgccatct cgtcagaaac aaatttgtcc
     1921 ccgtcgcagt cagctggttg ctgtaacgca gtcgccagga ggctccttgc tgtaccgctt
     1981 ccccctgacg ctgactgtgt gtgtcgcttc catcgacaga taaactcccc caccgcccga
     2041 gagatcctcc caaaccaagc gatgcagctt gatagtgcgt tgcactctgt ataccgccat
     2101 atgcagtgag attccacggc agaccataca tcaacgtagc ctgcgcgatc tgcgccttat
     2161 ccgttgcaga gtctgacgat cggtatcggc ccgccaacag gctgtacttc aaatatccct
     2221 ggtgcagtgc tatcgccggg gtctgatacg gcaccacaaa catttgtgta ctgccatcgg
     2281 cctcccacac ggtgacatgc agatcaccac tactgtctgt taccgacaga tcccgcagtg
     2341 caaacggtcc gggcgccacg gtggtgttgt aaatggtgta accattctgt ttgacctcca
     2401 cccgagcctg cgtgcgggca atcccacgca ctaccggagc aaactgccgc tcactgtagg
     2461 gcaccatgtt gtcatccgat gccaacatca caccggtaaa tggcacacta tcaaatatct
     2521 ccccctgcga agtcttttgc cccagagtca gacgactttt tagtgagtac agtccacgct
     2581 cagcataggt atatgctgcc tgccacttcc ccgacagttg actactccgc tgccagctgg
     2641 tcgcattgcg gacacgccac gcacctatat tgattcccgg ttgcagttgt acccaggaag
     2701 agttgtcacg ccccaccata tccattttgt aatccgtctg cgttgtcctc gcactgtagt
     2761 tcatcagaaa cgccggaata ccatcatccc aaagatcttc tggagcgatc cccttaaatt
     2821 ccggacgcaa cgccaactgc ggaatactca gttgcagttg ctgattattg atatccagta
     2881 ccgctttagc ctgtggaatg gcggtcagat ccgcacactc atctggggtc tttgctgctt
     2941 tccacaactg agggtaatct tccgttttta cgccgtagcg tgaaagctga ctgaccgtca
     3001 aacaagaagc cagaaaaggc gttccttgcc catccttttc taatttgaac accacatcac
     3061 gggtgtcgac acgtttacca ttcaccatta cgtccactcg ataagtccct ggctgttgta
     3121 ccccctggtt aaagagcgac atatcaaccc ctttcgctgc atcgcccaac attgatgcat
     3181 cgaatgtgta agtgtgcgca tttgcgcagt gaaccactcc cgcgataaac agtagcaagg
     3241 caggttgttt gaacttcata ttctgccgct aagcccctgg atttatttaa ggacgtagtg
     3301 gaacggatga ctttcaccac caaagtcagt aataactctc cactcgacat caccatgggc
     3361 actacctggc atatttagtg ttttgtcagc aaaagggggg atatactcaa gccctgtaat
     3421 gggctttccc cctactgtga cggaggctaa attcatgtaa aacggggtgg ggttctccac
     3481 cttaagtttg ttgcccgcct ccacccatct taaatttcct gcaacatctt ccggcgtccc
     3541 cttcacggca tccgggcgga aaatcagctt atcacagacg ttgatggaca aattgaggtc
     3601 aagggtcgcg cccttagcct gtgtatccga cggttcattt tcgggtggta ccgcctttac
     3661 acagacccac tgtaaagtct cacgatccgt tggcatgtca ccaccagtac ggacaatacg
     3721 cagttgactc tgctggttcg cttctaaacg aaatagaggc ggcatcacca aaaaaggagc
     3781 aggcgaactt ttgtctgctg ctttgactga agactgaacc aaaatagggt aattctgcgg
     3841 gttgctcacc gagagcgtgg ctccaactgt accagcgtga taaatcaccc gtgtagcccc
     3901 cagcttcacg ctgaatgatt tagtgtttaa acttaatttc tgctcagc
//
LOCUS       DAJVBX010000271         3937 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.271, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000271 DAJVBX010000000
VERSION     DAJVBX010000271.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3937)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3937)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3937
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.271"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            240..1073
                     /locus_tag="OPV72_004222"
     CDS             240..1073
                     /locus_tag="OPV72_004222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCR9916366.1"
                     /translation="MAKPSTSLLKRRLDIAEIVRKNGEIKVDDLAEMLSVSGVTIRND
                     LNYLEQQGYLKRSFGGAIYTAQPVRAAVSHEVVQSQALEHSVELELAKQVARLVCDDD
                     TVFLGAGEVLRKALPFLGDYRDLCLIINDLSHVAPARDYIDGEIVLLGGVLGRSGQAL
                     GGEIAIQSLQQFQPSCCLVMVDHISEDGTLNVKNESAAALLSECLRLSGQSIAVVAQR
                     PIHDIARYPVGKLNTLSAIITPQIVAAEYHSRFLADGLTNSYTNNECLTWINPTLHQA
                     R"
     gene            1084..2031
                     /locus_tag="OPV72_004223"
     CDS             1084..2031
                     /locus_tag="OPV72_004223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HCR9916367.1"
                     /translation="MNITIATLSELLVEFLAKKENQGFSSPGEFWGPYPSGAPAIFAD
                     QVAKLGFRSLLFSCVGNDAFGVMNITRLSRDGVNVQGISVLPNATTGSAFVSYRSQAQ
                     RDFIFNMPDSACGLLSADHLDETLLRQYRHFHIMGSSLFSFRLIDAVRKAISIVKENG
                     GTISFDPNIRKEMLKIREMSQAFEYILDYTDFFLPSDGELDYFGLSKSRDEEKIVARL
                     HKRGIAHVIIKRGARGASYYSKDEQHHVAGYPVKVVDPTGAGDCFGATFVSLFLAGYS
                     VPDALAHANAAGSLAISARGPMEGTSTLAQIKELMRQQN"
     gene            complement(2271..3842)
                     /gene="garD"
                     /locus_tag="OPV72_004224"
     CDS             complement(2271..3842)
                     /gene="garD"
                     /locus_tag="OPV72_004224"
                     /EC_number="4.2.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactarate dehydratase"
                     /protein_id="HCR9916368.1"
                     /translation="MANIEIRQESPSAFYIKVHETDNVAIIVNDHGLKAGTRFPDGLE
                     LTEHIPQGHKVALTDIPAHGEIIRYGEVIGYAVRDIPRGSWIDESLVELPKAPPLNTL
                     PLATKVPEPLPPLEGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKVIERDL
                     LPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNIALNPNFGGEVMVIGLGCEKL
                     QPERLLEGTEDVPAIAVENASIVRLQDEQHVGFKSMVDDILRVAERHLTKLNQRQRET
                     CPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTP
                     RAINEAVGKRLLDEMAWYDNYLDMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGK
                     SAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVP
                     VIKMATRTELANRWYDLMDINAGTIATGEETIEDVGWKLFHFILDVASGRKKTFSDQW
                     GLHNQLAVFNPAPVT"
BASE COUNT          944 a          947 c         1046 g         1000 t
ORIGIN      
        1 tgatcatcaa cacaaaagca ggataatttt tcttaaatga aagcaaatat gtggatttaa
       61 attttgtttt gtaagtaaat aggggatgtg aaaattctat aagtgattga ttttattgtg
      121 atgtttccca ttgagcattc ggtgacgtgg tgcaaaattg acatcccctg tcagaagttt
      181 aaaaatgaaa gttaaagcac gggataactt cccgacgaag cggaaaaaaa gggtatgttg
      241 tggcaaaacc atctaccagc ctgttgaaaa ggcgtctgga cattgccgaa atcgtccgta
      301 aaaacggcga aataaaagta gacgatttgg ctgaaatgtt atcggtttca ggggtaacga
      361 tccgtaatga tctcaattac ctggagcagc aaggctatct gaaacgctcc tttggcggag
      421 cgatttacac ggcccaaccc gtcagagcag cggtaagcca tgaagtggtg cagtcgcagg
      481 cgttagagca tagcgtcgag cttgaactgg ctaagcaagt tgcccgtctg gtctgcgacg
      541 acgataccgt gtttctgggg gccggagagg tgttgcgtaa agcgcttcct ttcctgggcg
      601 attatcggga tctgtgcctt atcatcaacg atcttagcca tgttgcaccg gcccgtgatt
      661 atatcgatgg tgaaattgtg ttgttgggcg gtgtactggg gcgcagtggt caggcgctgg
      721 ggggcgaaat cgccatccaa tctttgcaac aatttcaacc gtcatgttgt ctggtgatgg
      781 tggaccatat cagcgaggat ggcacgctca acgtgaaaaa cgaaagtgca gctgctttgc
      841 taagtgaatg cctgcgcctt agtggacaga gtattgccgt ggtggcgcag cgtccgattc
      901 atgatatagc gcgttatccg gtaggaaaac tgaatacgct gagcgcgatt attacgccac
      961 agattgtcgc cgctgagtac cactcacggt ttctggccga cggcttaacc aacagctata
     1021 ccaataacga atgtctgacc tggataaacc cgaccctgca tcaggcaaga tgaaggacaa
     1081 cgcatgaaca taacaatcgc aacattgagt gaattgctcg tcgagtttct ggcaaaaaaa
     1141 gagaaccagg gattttcctc accgggggaa ttttgggggc cgtatcccag tggggcgcct
     1201 gccatatttg ccgatcaggt tgctaaactt ggttttcgtt cattgttgtt tagctgtgtt
     1261 ggcaacgatg cctttggcgt tatgaatatt acccgattgt cgcgcgatgg cgtaaatgta
     1321 cagggaattt ccgtactgcc gaacgccaca acaggtagtg cttttgtcag ctaccgaagc
     1381 caggcccagc gagattttat tttcaacatg ccggacagtg cgtgcggttt gctgagtgcc
     1441 gaccaccttg atgaaacatt actcaggcaa tatcgccact ttcatattat gggatcgtca
     1501 ttattttcct ttcgtttgat cgatgccgta cgcaaggcga ttagcattgt aaaagaaaat
     1561 ggtggcacaa tttctttcga tcctaatatc cgtaaagaga tgctaaagat ccgcgaaatg
     1621 tcgcaggcct ttgaatatat tcttgattac acggatttct tcctgccaag cgatggcgaa
     1681 ctggattatt tcggcctgag caaatcccgc gatgaagaga aaattgtcgc aaggcttcac
     1741 aagcgtggaa ttgcccatgt catcattaaa cgtggcgccc gtggagccag ttactattca
     1801 aaagacgaac aacatcatgt ggctgggtat ccggtgaagg tggttgatcc tacaggcgct
     1861 ggcgattgct ttggcgcaac ctttgtcagc ctgtttcttg cgggatattc cgtacccgat
     1921 gctttagccc atgctaatgc cgcaggatcg ctggctatct ctgcgcgtgg gccgatggaa
     1981 ggcacgtcca cgctggcaca aattaaagaa ttgatgaggc agcagaatta agtaaaggtg
     2041 attaataggc tgtcgttata ttcgacatac ctcaaattgc atgtgctgcg actcaaatta
     2101 gtgagaaacg taaggttgcg cctggcatag aatttcaatt tattgaattt gaatggtttt
     2161 atggtgggtt aggtgttttt gccatatccg gtatgaacat ggcgcagttt atcaaacata
     2221 tgaaaacatg gcccttaagc catgttttgc gaggcgcttt ccagaataga tcaggtcaca
     2281 ggtgcggggt taaacactgc cagctggtta tgcaatcccc attgatctga gaaagtcttt
     2341 ttccggccgc tggcgacatc gagaataaag tgaaatagct tccagcccac atcttcgatt
     2401 gtctcttcac ccgtggcgat ggtgcctgca ttgatatcca ttaagtcata ccagcggttc
     2461 gccagctcgg tacgcgtcgc cattttaatg accggcaccg ccatcagccc gtacggcgtg
     2521 ccgcgtccgg tggtaaagac ctgtacggta atgccggaag cgacctgctg cgtgccgcag
     2581 acgaaatcgc tggcgggcgt cgcggcgtaa atcaggccgc gtttggtggg gcgctggccc
     2641 ggcgacaata cttcgacaat ggcgctctta cccgatttag cgatagagcc cagcgctttt
     2701 tccacgacgt tcgccaggcc gccttttttg ttgccggggg acgggttagc gctgcgatcg
     2761 gttttcccca tatcaaggta gttatcgtac caggccattt catccagtag gcgtttaccc
     2821 acggcttcgt tgatggcgcg cggcgtcaga agatgaatgg catcgcgcac ttcggtgacc
     2881 tccgagaaca tgacggtcgc gccgcagcgt accagcagat cggaagcata acccaccgcc
     2941 gggtttgccg tgacgccaga aaacgcatcg ctgccgccgc attgcatccc gacgaccagc
     3001 tcggaggccg ggcaggtttc gcgctggcgc tggttcagtt tcgtcagatg gcgttcggcg
     3061 acccgcaaaa tatcgtcgac cattgattta aagccaacat gctgctcgtc ctgtaaacgc
     3121 acaatactgg cgttttcaac ggcgatggcg gggacatcct cggtgccttc cagcagtcgt
     3181 tccggctgca gtttttcgca accgaggcca atcaccatca cttcgccgcc aaaattgggg
     3241 ttgagcgcga tattatgaat tgtgcgaatc ggcacgaccg ccgccggcgc gttgattgcc
     3301 acgccgcagc cgtacagatg gtttagccct acaacgccat cgacattcgg gtatttgggc
     3361 aggagatcgc gctcaatcac tttcaccaca taatcgacca cgcccgccac acagtgcacg
     3421 ctggtggtaa tgccaagcag atttttggtg ccgacgctgc catcggcgtt acgatagccc
     3481 tcaaacgtgt agccttccag cggcggcagc ggttccggta ctttggtcgc cagcggtagc
     3541 gtattcagcg gcggcgcttt tggcagttca accagcgact cgtcgatcca gcttccgcgc
     3601 gggatgtcgc gtaccgcata accgatgact tcgccataac ggatgatttc gccgtgagcg
     3661 gggatatccg tcagagcgac tttatggcct tgcggaatat gttcagtcag ttccaggcca
     3721 tccggaaaac gtgttccggc tttaaggccg tggtcattaa caataattgc gacattatcg
     3781 gtttcatgta cttttatata aaacgccgat ggcgattcct ggcgaatttc gatattggcc
     3841 attgttcaac attctccagc ctggatgata gaaataggat tatctatttt ggttatggtt
     3901 aaatcgttaa atctcaatat aagaaataaa gttcatg
//
LOCUS       DAJVBX010000272         3913 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.272, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000272 DAJVBX010000000
VERSION     DAJVBX010000272.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3913)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3913)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3913
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.272"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            115..801
                     /gene="istB"
                     /locus_tag="OPV72_004225"
                     /pseudo
     CDS             115..801
                     /gene="istB"
                     /locus_tag="OPV72_004225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000544830.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
     gene            complement(866..1027)
                     /locus_tag="OPV72_004226"
                     /pseudo
     CDS             complement(866..1027)
                     /locus_tag="OPV72_004226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013365374.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1114..1227)
                     /locus_tag="OPV72_004227"
     CDS             complement(1114..1227)
                     /locus_tag="OPV72_004227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010989119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HCR9916369.1"
                     /translation="MMPTDGNDNTRKQDGAVFGQPEVKPMPETLQCTEKWR"
     gene            complement(1347..2294)
                     /locus_tag="OPV72_004228"
     CDS             complement(1347..2294)
                     /locus_tag="OPV72_004228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCR9916370.1"
                     /translation="MMELINNRGMRDWMIFIKVAEVGNLSRAARELDISISAVSKSLS
                     RLENSIEVTLLRRDSHHLELTGAGQTAYASMKRITSSFQSLLDELRNPDKIIRGSIKF
                     SAPAIVCEFLANKWIWEFTASYPDTKIYLDSRERSDFFSKSLEFDELVFKSGIIESED
                     LVYRKISPLKLVLCASPKYIRKYGRISHPGDLENHIIVGLHNHGLSGPLTLFRQEESY
                     TISGAVNVHLSSNNLLSVLNLVLEGKGINLMTPAWLATKYLKNNELEIILPEWRVPDL
                     PIYLVWRHRQYYSPLFQRFLSFIEDKWNNRPQIDFLNDD"
     gene            complement(2786..3026)
                     /locus_tag="OPV72_004229"
                     /pseudo
     CDS             complement(2786..3026)
                     /locus_tag="OPV72_004229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309415.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PerC family transcriptional regulator"
     gene            complement(3109..>3913)
                     /locus_tag="OPV72_004230"
     CDS             complement(3109..>3913)
                     /locus_tag="OPV72_004230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HCR9916371.1"
                     /translation="LPVLMYHHVSDKPGQITLSPRTFRAQMKWLAESGWKTVTAAAVE
                     AFYHGARLPRKSVMLTFDGGWLDNWLQVFPVLQEFNLHAHLFLVTSLISDGPVRIPAG
                     EPVYSHDECQMLVKQGRVDEVMLRWSEVREMHLSGLVEFHSHTHTHRRWDQKPVSRNP
                     SDLLRVDILLSRKRMREMLGYCSQHLCWPEGWYCSDYIHVAEELGFTYLYTTERRMNN
                     PVIGSQRIGRINTKERKNVGWLKRRLFYHTTPGFSSLLARHKGARRIAD"
BASE COUNT         1101 a          988 c          873 g          951 t
ORIGIN      
        1 gtcccttacc tgtcaatgtt gtttacggtt cctttccccc ttttgtgcga gtaagcaaca
       61 tgaatataca agtcttaacg accaatgcct ctgtcagccc aaaataagtc gacattcctg
      121 tgcatggcgc tgcagcagga atagaacggc agacatcagc gcggaatgga atcccggctg
      181 aaacaggctc gtctgccatg agtcaaaacg ctggagcagt tcgacttcag cttccagcca
      241 ggcatcgatc gtaaggtcgt ccgggagttg gccggtctgg cgttcgtgga gcgctgcgag
      301 aatgtgatcc tgctggggcc cccggagtgg agaaaaccca cctggccgct gcccccggtg
      361 tgaaagcggc agatgtgggc catcgggtgt tgttcatgcc gcaggacagg ttggtagacg
      421 ctgatgaaag cgaagctgga aaaccgcctg gagcgccagc tacaacaact gagctatgcg
      481 cgggggctga tcctggacga aataggttac ctgccaatga ccagtgagga agccagtctg
      541 ttcttccgac tgctgaaccg acggtatgaa aaagcgagca ttatcctgac gtcaaacaaa
      601 ggcttcgcag actggggaga gatgttcggt gataacgtgc tggcaacagc gatcctggat
      661 cggctactgc atcactcaac cacactgaat atcaaaggag aaagttacca actgaaggaa
      721 aaacgcaaag tcggggcgct gaccaaaagc gcaacgccaa tcagtgaaga tgaaatggcg
      781 gaaagcggac agcagaagtg atcaaacagc ggatattaaa aatagcgaaa aacgaccata
      841 aatcctggcg ttgacatcct caagatttaa tatcagaagc ttccatgccg ccgtatccag
      901 acttccagtt gtccctggtg gcttcagaaa taccggcctc ccggtagaca tctttaacag
      961 tccgtccgga ttcaactgat ctaatcacag cgatgatctg gtgcgcagta atacgggctt
     1021 tacgcacagc gatctcctgc gttggcagat tgattatgcc ggatgatctc taaatgtgaa
     1081 tggctcgatt atgcgggata cttacagtgc aacctagcgc catttttcag tacactgcaa
     1141 cgtttctggc atgggcttaa cttccggctg cccaaaaaca gccccgtcct gtttccgggt
     1201 attatcattt ccgtcagtcg gcatcatgtt ttgtattggg catcgtcaaa agacgactgg
     1261 ccggccagtc gcatatctcg atgcctcaat tcagtcatca tcatgtgggt ttaagtcagg
     1321 aacgtgtcaa aaccattcca aacgagttaa tcatcattca gaaaatcaat ttgtgggcga
     1381 ttattccatt tatcttcaat aaaagacaga aagcgttgaa ataaaggaga ataatactga
     1441 cgatgacgcc atacaagata aatggggaga tctggaactc tccattcagg aagtataatt
     1501 tcaagttcat tattttttaa gtatttagtg gcaagccagg ccggagtcat gaggttgata
     1561 cccttccctt ctaaaaccaa attaagaaca ctcaaaagat tattggaaga taaatgaaca
     1621 ttaacagcgc cactaatagt gtatgattcc tcttgacgga aaagagtaag aggtccggaa
     1681 agaccatggt tgtgaagacc cacaataatg tgattttcca aatcgccagg atgtgagatc
     1741 ctgccatatt ttctgatata tttcggactt gcacaaagaa ccaactttaa agggcttatc
     1801 tttcgataca cgagatcctc actttcgatt atgccacttt taaaaaccag ctcatcaaac
     1861 tccagggatt tactaaaaaa atcgctacgc tctcgtgaat ccaggtagat ttttgtatcc
     1921 ggatagctag ctgtaaattc ccatatccac ttattggcaa gaaactcaca gacaatagcc
     1981 ggagccgaaa attttatact ccctctgata attttatccg gatttcgcaa ttcatccagc
     2041 aaggactgaa aggaagatgt tatccttttc atgcttgcat aggctgtctg accagctcca
     2101 gtcagctcta agtgatgtga atcgcgccga agtaaagtaa cctcaataga attctcaagg
     2161 cgactaagcg atttactgac agcagaaatg ctaatatcta attcccgcgc agcccgggaa
     2221 agattcccta cttccgccac tttaataaat atcatccaat ctcgcatacc acgattattg
     2281 atcagttcca tcattatctt ccgttgataa aagaaattct tatattaaag gagctatcaa
     2341 cgacttactg atgcgtcatt gtgtgcctca atgtccttga tatcatcata ataaaaaacc
     2401 tattggctgc aaaatagcat ctgaatcgat catgattttg catccatctc cggttactaa
     2461 ttgaacctgt ttaccactca gtgtaaatac cctatctcag aagcgatcgt caaggttgtc
     2521 gccgaaccag atctcaataa taaagtggtt cattgtcatg cgcccgttct gcaaaggcat
     2581 tctccttttc tgtgacgcag tctggagcgc attaattgta tcgttcacct aacaaagtat
     2641 cccgtggaaa caagcaaaac atcgccagat tattcttact tgagtccccc acccggctcg
     2701 acattatttg tgaaagcgga ggaaacagaa cagacggttt aaataagacg cttactcaaa
     2761 acataaacct atgtgcaggc tcctctcatt tcgtcacgtc gctgatatcc agctttactg
     2821 gtgccagggg aagatatctg cgcaaggcaa taattccggc gcaacaacaa ccactcccgc
     2881 tgggcctctg tacattcaaa atcgcccatg accaaaagcc agcgggtaga agccctgcgc
     2941 cagtgacctg ctgcctccag attctgcgca accgggtcta tcacggcttc cggtgttatc
     3001 ttatttctgc tcaaaatcag caccatcatt tgggatatag cctacaaccc ctgcccgccg
     3061 atgatggggg aggattcggt atgcagcact ttcatcctgg tctccggctc agtcagctat
     3121 ccgacgtgcc cccttatgcc gggccagcag cgaagaaaat ccgggcgtgg tgtgataaaa
     3181 caggcgacgt ttcagccagc ccacattctt tcgctccttt gtgttgatac gaccaatacg
     3241 ctgtgaaccg atgactggat tgttcatacg cctttctgtg gtatacaggt atgtgaaccc
     3301 cagctcttca gccacatgaa tataatcaga acaataccag ccctcaggcc agcacagatg
     3361 ctgactgcag taacccagca tctccctcat ccgcttacga ctaagaagaa tatcgacacg
     3421 aagcaaatcc gacggattac gggacacagg cttctggtcc cagcgtcggt gggtgtgcgt
     3481 gtgcgaatga aactcaacaa ggccactgag gtgcatctcc cggacctctg accagcgcag
     3541 catgacctca tcaacccggc cttgtttaac cagcatctga cactcatcat gagagtacac
     3601 cggttcgcct gcaggaatac gaaccggtcc gtcactgatc aaactggtca caagaaagag
     3661 atgcgcatgc agattaaact cctgcagcac cggaaaaacc tgcaaccagt tatccagcca
     3721 gccgccatca aaagtcagca tgacgctttt acgaggcaat cttgcaccat gataaaaagc
     3781 ttccaccgct gcagcagtaa cggttttcca gccagattca gccagccatt tcatctgcgc
     3841 ccggaacgta cggggagata aggttatctg tccgggttta tcactgacat ggtgatacat
     3901 taataccggt aaa
//
LOCUS       DAJVBX010000273         3897 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.273, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000273 DAJVBX010000000
VERSION     DAJVBX010000273.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3897
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.273"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(158..1723)
                     /gene="ahpF"
                     /locus_tag="OPV72_004231"
     CDS             complement(158..1723)
                     /gene="ahpF"
                     /locus_tag="OPV72_004231"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HCR9916372.1"
                     /translation="MLDTNMKTQLRAYLEKLTKPVELIATLDDSAKSAEIKELLAEIA
                     ELSDKVTFKEDNTLPVRKPSFLITNPGSQQGPRFAGSPLGHEFTSLVLALLWTGGHPS
                     KEAQSLLEQIRDIDGDFEFETYYSLSCHNCPDVVQALNLMAVLNPRIKHTAIDGGTFQ
                     NEITERNVMGVPAVFVNGKEFGQGRMTLTEIVAKVDTGAEKRAAEALNKRDAYDVLIV
                     GSGPAGAAAAVYSARKGIRTGLMGERFGGQVLDTVDIENYISVPKTEGQKLAGALKAH
                     VSDYDVDVIDSQSASKLVPAATEGGLHQIETASGAVLKARSIIIATGAKWRNMNVPGE
                     DQYRTKGVTYCPHCDGPLFKGKRVAVIGGGNSGVEAAIDLAGIVEHVTLLEFAPEMKA
                     DQVLQDKVRSLKNVDIILNAQTTEVKGDGSKVVGLEYRDRVSGDIHSVALAGIFVQIG
                     LLPNTHWLEGVLERNRMGEIIIDAKCETSVKGVFAAGDCTTVPYKQIIIATGEGAKAS
                     LSAFDYLIRTKIA"
     gene            complement(1965..2528)
                     /gene="ahpC"
                     /locus_tag="OPV72_004232"
     CDS             complement(1965..2528)
                     /gene="ahpC"
                     /locus_tag="OPV72_004232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003858764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit C"
                     /protein_id="HCR9916373.1"
                     /translation="MSLINTKIKPFKNQAFKNGEFIEVTEKDTEGRWSVFFFYPADFT
                     FVCPTELGDVADHYEELQKLGVDVYSVSTDTHFTHKAWHSSSETIAKIKYAMIGDPTG
                     ALTRNFDNMREDEGLADRATFVVDPQGIIQAIEVTAEGIGRDASDLLRKIKAAQYVAA
                     HPGEVCPAKWKEGEATLAPSLDLVGKI"
     gene            2968..3714
                     /gene="dsbG"
                     /locus_tag="OPV72_004233"
     CDS             2968..3714
                     /gene="dsbG"
                     /locus_tag="OPV72_004233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbG"
                     /protein_id="HCR9916374.1"
                     /translation="MIKRTLLLAMLPILAHAEELPALVKAIEKQSITILKSFEAPGGM
                     KGYLGKYQDMGVTIYLTPDGKHAISGYMYNEKGENLSNALIEKEIYAPAGREMWQKME
                     KASWILDGKKDAPVVLYVFADPFCPYCKQFWQQARPWVESGKVQLRTLLVGVIKPESP
                     ATAAAILAAKNPAKTWHDYEASAGKMKLEVPASIPPAQMKVINQNQQLMDDLGANATP
                     AIYYMNKDKILQQVVGLPEKAQLDAMMGQP"
BASE COUNT          943 a         1043 c          968 g          943 t
ORIGIN      
        1 tctgttatta acagacggtt tcagagtatt gataatgaag aacgtgtttt acccggtggc
       61 gttccccagg cataaacacc gcaggcccga atagcttaca ctatcgggcc atttacgatg
      121 gccagttaac tggccttgca ggtgtgctta cttcttttta tgcgattttg gtgcgaatca
      181 gataatcaaa ggcgctcaac gaggctttcg ccccttcgcc tgtggcgatg ataatctgtt
      241 tgtaaggaac ggtggtgcaa tcgcctgcgg cgaagacgcc cttaacgctg gtttcacatt
      301 tggcgtcaat aatgatctcg cccatgcggt tacgctcaag cacgccttcc agccagtggg
      361 tattcggcaa aagaccaatc tgcacaaaaa ttcctgccag cgcgacgcta tgaatatcgc
      421 cgctgacacg gtcacgatac tccagtccca ccactttcga accgtcgccc ttcacttctg
      481 tcgtttgcgc attcaaaatg atatcgacat ttttcaggct acgcactttg tcctgtagca
      541 cctgatccgc cttcatctcc ggcgcgaact ccagcaacgt aacatgttct acaatacctg
      601 ccagatcgat agccgcttcg acgccggagt tgccgccgcc gatgaccgcc acacgcttgc
      661 ctttaaataa cggaccgtcg cagtgcgggc aataggtgac gcctttggtg cgatactgat
      721 cctcgcccgg cacattcata ttgcgccatt tcgcgccggt ggcgatgatg atactgcgcg
      781 ctttcaagac tgcgccggac gccgtttcaa tctgatgcag gccgccttct gtcgctgccg
      841 gaaccagttt acttgcgctc tggctgtcga taacgtcaac gtcgtaatcg ctgacatgcg
      901 ctttcagcgc gcccgccagt ttctggcctt cggttttcgg caccgagata tagttttcga
      961 tatccacggt atccagcacc tgaccgccga agcgctcgcc catcagaccg gtacggatgc
     1021 ctttgcgcgc cgagtagacc gccgccgccg cgcccgccgg gccggagccg acaatcagca
     1081 cgtcatacgc atcgcgtttg ttcagcgctt ccgccgcacg tttttctgcg ccagtatcca
     1141 ctttagcgac aatctcggtc agagtcatac gtccctggcc gaactcttta ccgttgacaa
     1201 acaccgccgg aacgcccatc acgttacgtt cggtgatttc gttctggaag gtgccgccat
     1261 caattgccgt atgtttaata cgcgggttca gcaccgccat caggttcagc gcctgcacta
     1321 cgtccgggca gttatggcag gagagtgaat aataagtttc gaattcaaaa tcgccgtcaa
     1381 tatcgcgaat ctgctccagc agcgactgcg cttcttttga cggatgaccg ccggtccaca
     1441 gcaacgccaa aaccagcgag gtaaattcgt ggcccagcgg agaaccggca aagcgcggcc
     1501 cctgctgaga gcctggattc gtaatcagga aagacggctt gcgcaccggc agagtattgt
     1561 cttctttaaa tgtgactttg tcggacagct cggcgatttc agccagcagt tccttgattt
     1621 ccgccgattt agcgctgtca tccagcgtgg caatcagctc aacaggtttg gtcagtttct
     1681 caaggtaagc cctgagctgg gttttcatat ttgtgtcgag cattcttctt ccctctctga
     1741 aaacatcatc atgcaagccg acttcgcggg actgcattaa tgcaacttgc gtcatggtgc
     1801 tgaaatgaaa tgggcgcgga tgcgcccatg actgaaacaa tttccaaagt atttcacgtc
     1861 agagtaaggc ggctagcctg agaatccccg ggagcttact gaagtaagtg accggggtga
     1921 gcaggcaacg ccaacgcagc tatggcgtga aagacgacgg aaatttagat tttaccgacc
     1981 aggtctaagg atggagccag agtcgcttca ccttctttcc atttcgccgg gcatacttcg
     2041 cctgggtgag cggcaacata ctgtgctgct ttaattttac gcagcaggtc agacgcgtca
     2101 cggccgatac cttcagcggt aacttcgatc gcctgaatga taccctgcgg gtcaacaaca
     2161 aaggtcgcac ggtctgccag gccttcatct tcacgcatgt tgtcgaagtt acgggtcagg
     2221 gcgccagtcg ggtcgccgat catcgcatat ttgatttttg cgatagtttc agagctgctg
     2281 tgccatgctt tgtgcgtaaa gtgagtatcg gttgagacgg aataaacgtc tacgcccagc
     2341 ttctgcagtt cttcgtaatg gtcggcaacg tcacccagtt cagtcgggca aacaaaggta
     2401 aaatcggccg ggtagaagaa gaagacgctc cagcggcctt cggtatcttt ctcggtgact
     2461 tcaatgaatt caccgttttt gaacgcctgg tttttgaaag gtttgatttt ggtgttaatt
     2521 aaggacatct atacttcctc cgtgttttcg ttgaggagta agttaacgaa attttgctga
     2581 ttcggctaat gcgtttccat tatcaaatca ataagcgtta actaacaacc cgattcgggc
     2641 gacattgtga acactgcgcc ctgtcagcca tctaaagtaa aaaggccgcc tgacaggcgg
     2701 ccccattacc tgaactaccc gtaggtaact tcagagccag tacgactcgt cttgcaaatg
     2761 gcaggcgtat tgcctgccac tcgaaatcca tagcgtatat gctggctaag tgttgcgctc
     2821 tacattacct taacaaaggc tgtaacagcg aaaaggatta catcacccca gcacagaaag
     2881 ggcaatcctg gcacgccagc tcttacctat gtctgcgata ggcatcatca ttaatactct
     2941 tttcgctttg atattaaaaa gaaaaatatg attaaacgta cattgctgct tgctatgctg
     3001 cccattctcg cccacgcgga agaactgcct gcgctggtta aagccattga aaaacagagc
     3061 ataacaatcc tgaaatcctt cgaggcgccg gggggcatga agggctatct cggaaagtat
     3121 caggatatgg gcgtcacgat ttacctgacg ccggacggta aacacgcgat ttccggctat
     3181 atgtataatg aaaaaggtga aaatcttagc aacgccctga tagaaaaaga gatctatgcg
     3241 ccagccggac gtgaaatgtg gcagaaaatg gaaaaagcgt catggatact cgacggtaaa
     3301 aaagacgcgc cggtggtgct gtatgtcttt gccgatcctt tctgccccta ttgtaagcag
     3361 ttttggcaac aagctcgtcc gtgggtcgaa tccggcaagg tacaattacg cacattactg
     3421 gtcggcgtga ttaaaccgga aagcccggcc acagccgcag cgattttagc cgcgaaaaac
     3481 ccggcgaaaa cctggcatga ctatgaagcc tccgcaggaa agatgaagct ggaggttcct
     3541 gcgtccatcc ccccggcgca gatgaaagtc attaatcaga atcagcagtt aatggacgat
     3601 cttggcgcta acgcgacgcc agcaatttat tacatgaata aagataagat tttgcaacag
     3661 gttgttggtt taccggaaaa agcgcaactg gacgccatga tggggcagcc ttaacgcaga
     3721 aattagcaag gcagaagctt aaccgtacca cgcccgacag cgctacgttt gtcgggccaa
     3781 ccacctcccg gtattaacgc gacgccagac caaaatgtca tccggcacag cctttttagg
     3841 ctaacggcgt gattatatca gggtacgtta tgtccgcctt taccgtaatt atttact
//
LOCUS       DAJVBX010000274         3893 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.274, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000274 DAJVBX010000000
VERSION     DAJVBX010000274.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3893
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.274"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..1309)
                     /gene="asnS"
                     /locus_tag="OPV72_004234"
     CDS             complement(<1..1309)
                     /gene="asnS"
                     /locus_tag="OPV72_004234"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HCR9916375.1"
                     /translation="MSVVPVADVLQGRVAVDQEVTVRGWVRTRRDSKAGISFLAVYDG
                     SCFDPVQAVINNSLPNYNEEVLHLTTGCSVVVTGKVVASPGQGQSFEIQATKVEVAGW
                     VEDPDTYPMAAKRHSIEYLREVAHLRPRTNLIGAVARVRHTLAQALHRFFDEQGFFWV
                     STPLITASDTEGAGEMFRVSTLDLENLPRNDQGRVDFDKDFFGKESFLTVSGQLNGET
                     YACALSKIYTFGPTFRAENSNTSRHLAEFWMLEPEVAFADLEDNARLAEAMLKYVFKA
                     VLEERADDMKFFAERVDKDAIARLERFVSTDFAQVDYTDAVAILERCGKTFENPVFWG
                     VDLSSEHERYLAEEHFKAPVVVKNYPKEIKAFYMRLNEDGKTVAAMDVLAPGIGEIIG
                     GSQREERLDVLDARMAEMGLNKEDYWWYRDLRRYGTVPHSGFGL"
     gene            complement(1510..1971)
                     /locus_tag="OPV72_004235"
     CDS             complement(1510..1971)
                     /locus_tag="OPV72_004235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HCR9916376.1"
                     /translation="MKLDAWDKNILTLLQRDNRLSQREIAEQVNLSPSAVNRRIAALE
                     EAGIIKGNVSLVDAGKVGRPVTIVVQVVIENERFNLLEEARQRFVSCPQVQQVYYVTG
                     DFDFLLVLNVRDMAEYETLTRELFFSSGNIKSFKTIVVMQNAKQEMRVLIE"
     gene            2289..3504
                     /gene="dpaL"
                     /locus_tag="OPV72_004236"
                     /pseudo
     CDS             2289..3504
                     /gene="dpaL"
                     /locus_tag="OPV72_004236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459977.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
     gene            3750..>3893
                     /locus_tag="OPV72_004237"
     CDS             3750..>3893
                     /locus_tag="OPV72_004237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HCR9916377.1"
                     /translation="MLEQLSQLFEFLWGGPLFLCVIGIGFYFTVRLKFFQIINLKEIY
                     RNTI"
BASE COUNT         1045 a          915 c          915 g         1018 t
ORIGIN      
        1 ccaggccaaa gccggaatgc ggtacagtac cgtagcgacg caagtcgcga taccaccagt
       61 aatcctcttt attcagcccc atttcggcca tacgggcatc cagcacatcc agacgctctt
      121 cacgctggga accaccgatg atttcgccga ttcccggcgc cagcacatcc atggccgcca
      181 cggttttgcc atcttcgtta aggcgcatgt aaaacgcttt aatttctttc ggatagtttt
      241 tcaccactac cggcgctttg aaatgctctt ccgccagata acgttcgtgt tcggaagaaa
      301 ggtcgacgcc ccagaacacc gggttttcaa atgtcttacc acagcgttcc agaatggcga
      361 ccgcatcggt gtaatccacc tgagcaaagt cggtggagac aaaacgctcc agacgagcga
      421 tagcgtcttt atccacgcgt tcggcaaaga acttcatgtc atccgcacgc tcttccagaa
      481 ccgccttgaa gacatatttc agcatggctt ccgccagacg ggcgttgtct tccagatcgg
      541 cgaacgccac ttccggctcc agcatccaga actccgccag gtggcggctg gtgttggaat
      601 tttccgcgcg gaaggtcggc ccaaaagtat agattttgga cagcgcacag gcataggttt
      661 caccattgag ctggccggag acggtcagga atgattcttt gccaaaaaag tctttgtcaa
      721 aatctactct gccctggtcg ttacgcggca ggttttccag atccaacgtt gagacgcgga
      781 acatttcgcc agcgccttcg gtatcggaag cggtaatcag cggggtagag acccaaaaga
      841 aaccctgctc atcgaagaag cgatgcagcg cctgcgccag agtatggcgg acgcgcgcta
      901 ccgcgccaat caggttggtg cgcgggcgca gatgcgcgac ttcacgcaga tactcaatgc
      961 tatggcgttt tgccgccatc gggtaggtat ccggatcttc cacccagcct gcgacctcta
     1021 ctttcgtggc ctggatttcg aaactttgcc cctgtcccgg cgacgcgaca accttacctg
     1081 ttactaccac ggagcagcct gtcgtcaggt gtaatacttc ttcattataa ttgggcagag
     1141 aattattaat gacagcctgt acaggatcaa agcaggagcc gtcataaacg gcgaggaagg
     1201 agatgccagc ttttgaatct cggcgggtac gcacccatcc gcgcacggtg acttcttggt
     1261 caacggctac gcggccctgg agtacgtcgg ctacaggcac aacgctcata atattctctc
     1321 tagttaatag tcggaaaaaa taaacacttg tccacccgaa atgggggtat tcctatgtta
     1381 cctggcatct gcaatcagac aagcagaaat cgcatctgga agcaggtttt cagaaagaaa
     1441 cctgtaaaaa gttcgcacct gctcgcgaac aattgagaat ttaggctggt tttgtaagct
     1501 ttgcgcacgt tactcgatca ggacgcgcat ctcttgcttg gcgttttgca tcacgacaat
     1561 cgttttaaaa gacttaatat tgcctgagga aaagaaaagc tcacgggtaa gtgtttcata
     1621 ttccgccatg tcacgaacat tgagcaccag taaaaagtcg aaatcgcccg ttacgtagta
     1681 gacctgctgc acctgcgggc aactgacaaa ccgttgacga gcctcttcca gtaaattgaa
     1741 tcgctcgttt tcgatcacca cctgcaccac aatcgtgacc gggcgtccca ctttgccagc
     1801 atcaacaagg ctgacattgc ctttaattat gcccgcctcc tccagtgccg cgatacgacg
     1861 attcactgcc gaaggtgaaa gattgacctg ttcggcgatt tcccgctgag aaagacgatt
     1921 atcgcgttgc aataatgtca gaatgttttt atcccaggcg tcaagcttca tatcgcaaat
     1981 aacctcttta atgtgatgac tatcactgtg cgcaattttg ccgcgtccag gccgttaaaa
     2041 aaaggtgaaa attgcacgac gatgggcatt ttcgcgccat ttaacagcaa taagcatagt
     2101 actatcataa tcagcggaat aaagaaaagg acgtaataga tattgtgcga ctcttttatc
     2161 agtacggttt attaaagtga ggataaccac tactacagcc acaaaacgcg agttctttac
     2221 ttgtttctac tcaataattg ccaaaaacat attatttcaa taaataaact ttaacaaaag
     2281 gtatcattat gcatgagctt attaaatacc agtttaatac acgtcggaaa aaatatggta
     2341 caggagcggc tttaagtttg cttaacggaa atgttgggcg tgaggtgtta gcatttcata
     2401 aaaaattacc caattatgcc gttacgccgt tacataatct ggcgcatcta agccggcggc
     2461 ttggactagg gtccatccat attaaagatg agtcctggcg ttttggtctg aatgctttta
     2521 aaggtctggg cggctcttat gctgtaggaa aatatctcgc tgataaattg caatgtgata
     2581 ttaactcgtt aagttttgct gcccttaaca ctcctgagat taaagaaaaa attaaagatt
     2641 gtgtttttgt taccgcgacg gatggcaatc atggccgtgg tgtggcgtgg gcggcggagc
     2701 aattaggtct aaaagccgtc gtttatatgc ctaagggatc atcgttaatc tgggcagaga
     2761 atattcgcca tcatggagct gaatgcacca tcaccgatct gaactacgat gatgcagtgc
     2821 gactggccca tagaatggcg caaacaaaag gctgggtgct tttgcaggat acagcctgga
     2881 cagggtatga agagatccca acatggatta tgcaaggcta tatgatacta gcggttgaag
     2941 cttatgagca gctcgcagaa acaaacagtc cgttgccaac ccaccttatt ttacaagcgg
     3001 ggggtgggat catttgctgg cagtgttatg ggttattttg ttgaaaaaat gcaggaaaat
     3061 acccctaata ttattgtggt tgagccgcat caggccaact gtctttatca atccgcagtt
     3121 atgaatgatg gtcaacctca ctgcgtcact ggcgatatgg cgacgataat ggccgggctt
     3181 gcgtgtgggg agccgaatat tatcagttgg cctattattc gggacaacac cagttgtttt
     3241 atttccgctg atgattgtct ggcggctaag ggtatgcgca ttgctgccgc gccgcgtcca
     3301 ggcactgata cgccttttat ttccggcgag tccggagcta ttggcgtagg gttactttat
     3361 gagttgatga acaatatgca ttatcaggat cttgctaatc gcttacagct tgatgccaat
     3421 gctcatgttc tgcttattag caccgaaggc gatacgtccc cagatattta tgaagatata
     3481 gtctggaacg gacgcagtgc ttaaacatta cgactaaaaa attagataat aaaggcagca
     3541 tgtaaaaaac gcgtttttta tacgcataat aaacctaatg caggaagcaa aacttcataa
     3601 caatatacca ttaaaacggc atttagtgag taagggatgc tcctacccgc tgactttcca
     3661 gtttagtgtt gttggcaaaa ttcaggatta cgctgaactg gaaagattat ttctgagact
     3721 gaacgaatta atttaaatcc gaggtcatta tgttagagca actttcacaa ctctttgaat
     3781 ttctatgggg tggcccatta tttttgtgtg tcatcggcat tggcttttat tttacagtac
     3841 gcctcaaatt tttccagatt atcaatttaa aagaaattta ccgtaataca att
//
LOCUS       DAJVBX010000275         3879 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.275, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000275 DAJVBX010000000
VERSION     DAJVBX010000275.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3879)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3879)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3879
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.275"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..1636
                     /gene="dpiB"
                     /locus_tag="OPV72_004238"
     CDS             <1..1636
                     /gene="dpiB"
                     /locus_tag="OPV72_004238"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="sensor histidine kinase DpiB"
                     /protein_id="HCR9916378.1"
                     /translation="FPFFRQLAFPLRIFLLILVVSVFIVAALAQYLSASFEDYLASHV
                     RDMAMNQAKIIASNDSIIAAVKNRDYKRLAIIANKLQRGTDFDYVVIGDRHSIRLYHP
                     NPEKIGYPMQFTKPGALERGESYFITGKGSIGMAMRAKTPIFDNEGNVIGVVSIGYLV
                     SKIDSWRLDFLLPMAGVFVLLLVVLMLLSWFFAAHIRRQMLGMEPKQIARVVRQQEAL
                     FSSVYEGLIAVDPEGHITAINRNARKMLGLPSPGRQWLGKLIAEVVNPADFFTCQIAE
                     RRQDVMANFNGLSVIANREAIRSGEELLGAIISFRSKDEIATLNAQLTQIKQYVESLR
                     TLRHEHLNWMSTLNGLLQMKEYDRVREMVQGESQAQQQLIDSLRGAFADRQVAGLLFG
                     KVQRARELGLKMVIVPGSQLHQLPEGLDSTEFAAIVGNLLDNAFEASLRTQEGDNTIE
                     LFLSDEGDEVVIEVADQGCGVPEALREKIFEQGVSTRADEPGEHGIGLYLIASYVGRC
                     GGVITLEDNDPCGTLFSLFLPKVKKNDDRTINPIDR"
     gene            1605..2285
                     /gene="dpiA"
                     /locus_tag="OPV72_004239"
                     /gene_synonym="citB"
     CDS             1605..2285
                     /gene="dpiA"
                     /locus_tag="OPV72_004239"
                     /gene_synonym="citB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component response regulator DpiA"
                     /protein_id="HCR9916379.1"
                     /translation="MTEPLTLLIVEDETLLAEMHAEYIRHIPGFNQIWLAGNLAQARM
                     MIDRFKPGLILLDNYLPDGKGITLLHELMQSRYPGGVVFTTAASDMETVAEAVRSGAF
                     DYLVKPIAYERLGQTLTRYQQRRRMLASADSASQKQIDEMFNAYARGEPKGDLPTGID
                     ALTLNAVMKLFADPTVRHTAETVAQALTISRTTSRRYLEYCASRHLIVAEIIHGKVGR
                     PQRIYHGG"
     gene            complement(2339..3724)
                     /gene="dcuC"
                     /locus_tag="OPV72_004240"
     CDS             complement(2339..3724)
                     /gene="dcuC"
                     /locus_tag="OPV72_004240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic C4-dicarboxylate transporter DcuC"
                     /protein_id="HCR9916380.1"
                     /translation="MLTVIELLIGVVVIVGVARYIIKGYSATGVLFVGGLVLLIISAL
                     MGHKVLPASETSTGYTATDIVEYIKILLMSRGGDLGMMIMMLCGFAAYMTHIGANDMV
                     VKLASKPLQYINSPYLLMIAAYFVACLMSLAVSSATGLGVLLMATLFPVMVNVGISRG
                     AAAAICASPAAIILSPTSGDVVLAAKAAEMPLIDFAFKTTLPISIAAIIGMAIAHFFW
                     QRYLDKKENISHEMLDVAEITTTAPAFYALLPFTPIIGVLIFDGKWGPQLHIITILVI
                     CMLLAAVLEFVRGFNTQNVFSGLEVAYRGMADAFAGVVMLLVAAGVFAQGLSTIGFIQ
                     SLISIATSFGSASIILMLVLVILTMLAAMTTGSGNAPFYAFVEMIPKLAHSSGINPAY
                     LSIPMLQASNLGRTISPVSGVVVAVAGMAKISPFEVVKRTSVPVIVGLLIVIIATEIM
                     VPGASSAVTGG"
BASE COUNT          983 a          958 c         1082 g          856 t
ORIGIN      
        1 gtttcctttt tttcggcaac tcgcgtttcc gttacgtatt tttctgctca ttctggtggt
       61 ttctgttttc atcgtggcag cgttagcaca atatttgtct gccagtttcg aagattatct
      121 ggcgtcccat gttcgtgaca tggcgatgaa tcaggcaaaa attattgctt ctaacgacag
      181 cattatcgct gccgtaaaaa accgggacta taaacgcctg gcgataattg cgaataaact
      241 gcagcgcggg acggattttg actatgtggt gataggcgat cgccactcga tccggcttta
      301 ccatccgaat ccggaaaaaa tcggctatcc catgcagttt acgaaacccg gcgcgctgga
      361 aagaggagaa agttatttca ttaccggtaa gggctcaata gggatggcga tgcgcgccaa
      421 aacgcctatc tttgacaacg aaggcaacgt gatcggcgtt gtttcaattg gctatctggt
      481 cagtaaaatc gactcctggc ggctggactt cttattaccg atggcggggg tttttgtcct
      541 gttgctggtg gtattaatgc tgctttcctg gtttttcgcc gcgcatatcc gccgacaaat
      601 gctgggcatg gagccgaaac agattgcgcg cgtggtacgc cagcaggagg cgttatttag
      661 ctcggtttat gaagggctga tcgccgttga tccggaggga catatcaccg cgattaaccg
      721 caatgcgaga aaaatgttgg ggctgccgtc gccggggcgt cagtggctgg gcaagctgat
      781 agcggaagtc gtcaatccgg cagacttttt tacctgccag atcgcagaaa gacgccagga
      841 cgtgatggcc aacttcaatg gcctgagcgt catcgccaat cgtgaggcta tccgttccgg
      901 cgaggagctg ctgggcgcta ttattagttt tcgcagcaaa gatgaaatcg cgacgttgaa
      961 cgcgcagcta acccagatta aacagtatgt tgagagcctg cgcacgctac gccatgagca
     1021 cctgaactgg atgtcgactc tgaacggcct gctgcaaatg aaagagtatg atcgggtcag
     1081 agagatggtg cagggcgaat cgcaggcgca gcagcaactt attgatagtt tacgcggcgc
     1141 cttcgccgat cgtcaggtgg ccggtttgct gtttggcaaa gttcagcgcg cgcgtgaact
     1201 ggggctcaag atggtgattg ttcccggcag ccagttacat caactgccgg aggggctgga
     1261 tagcacggag ttcgccgcca tcgtcgggaa tctgctggat aacgcgtttg aggcgagttt
     1321 acgtacacag gaaggcgaca ataccatcga acttttcctg agcgacgagg gcgacgaggt
     1381 ggtgatagag gtcgccgacc agggctgcgg cgttcctgaa gcgctgcggg aaaaaatttt
     1441 tgagcagggc gtaagtaccc gagctgacga acccggtgag catggtatcg ggttatatct
     1501 gattgcaagt tatgtggggc gctgtggcgg ggtcattacg ctggaagaca atgatccttg
     1561 tggcacctta ttttctttat tccttccgaa agtgaaaaaa aacgatgaca gaaccattaa
     1621 ccctattgat cgttgaggat gaaacgctgc tggcggaaat gcacgcagaa tatatccgcc
     1681 atattcctgg ctttaaccag atatggctgg cgggcaatct ggcgcaggcg agaatgatga
     1741 ttgaccggtt caaacctgga ttaattctgt tggataatta tctgccggat gggaagggga
     1801 ttacgctgct gcatgaatta atgcagtcgc gctatcccgg cggcgtcgtg tttacgaccg
     1861 ccgccagtga catggagacg gtagcggaag cggtacgtag cggcgcgttt gattatctgg
     1921 tcaaacctat tgcttatgag cgtttggggc agacgctgac ccgttatcaa cagcgcagac
     1981 gtatgctggc gagcgcggat agcgcaagcc agaagcagat agatgaaatg ttcaacgcct
     2041 atgcgcgcgg cgaaccgaaa ggggatttgc cgacaggtat tgatgcctta acccttaatg
     2101 cggtgatgaa gctgtttgcc gatccaaccg tacgccatac ggctgaaacg gtcgcgcagg
     2161 ccttaacgat aagccgcacc acatcccgac gctacctgga atattgcgcg agtcggcacc
     2221 tgattgtcgc agagattatt catggcaaag tgggcaggcc gcagcgtatt tatcacggcg
     2281 gctaagcccg ctttaagatg ccggagcgat gttttccctc gccccggctt accggctatc
     2341 agccgccggt gacggcggaa gaggcgcctg gcaccataat ttccgtagcg ataatgacga
     2401 tcaacagacc gacgatgacc ggaacggacg tgcgcttcac cacttcaaac ggtgatattt
     2461 tagccatccc ggcgacagcg accacgacgc cggagaccgg cgaaatcgtg cgccccaggt
     2521 ttgaggcttg cagcattggg atggataaat aggctgggtt gataccggag gagtgcgcca
     2581 gtttagggat catctcaaca aaggcgtaaa aaggcgcatt gcctgaaccg gtggtcatcg
     2641 cggccagcat ggttaaaatc actaagacca gcatcagaat aatgctggcg gacccaaaag
     2701 aagtggcaat cgagatcaga ctttggataa agccaatggt gctcagcccc tgggcgaaaa
     2761 cgcccgccgc gaccagcagc atcacaacgc cggcaaacgc atccgccatg ccgcgataag
     2821 ccacttccag gccggaaaac acattttgcg tgttgaagcc gcgcacgaat tccagcacgg
     2881 cggccagcag catacagatg accagaatgg taataatgtg caactgcggc ccccatttac
     2941 cgtcaaaaat cagtacgccg ataatgggcg tgaacggcaa aagggcataa aacgccgggg
     3001 ccgtggtggt aatctccgcc acgtccagca tctcatgtga aatgttctct tttttatcca
     3061 gatagcgttg ccagaaaaaa tgcgcaatcg ccataccgat aatggcggcg atggaaatcg
     3121 gcagcgtggt tttgaacgcg aaatcgatta acggcatctc cgccgctttt gcggctaaaa
     3181 ccacatcgcc agacgttggc gagaggatga tggcggccgg cgaagcgcaa atagccgccg
     3241 ccgcgccgcg gctaatgccg acgttgacca tcaccgggaa gagagtagcc atgagcagta
     3301 cgccaagccc cgtcgcggaa gagacggcca gcgacatcag gcaggcgaca aaataggcgg
     3361 caatcatcaa caggtagggc gagtttatat actgtaaagg tttcgacgcc agcttcacga
     3421 ccatatcatt tgcgccgata tgcgtcatat aggcggcaaa gccgcacagc atcatgatca
     3481 tcatgccaag atcgccgccg cgactcataa gcaaaatttt gatgtattca acaatatctg
     3541 ttgcggtata gccggtactg gtttcgctgg caggtaatac cttatgcccc atcagcgcgc
     3601 tgataataag cagaaccaga ccgccgacaa ataaaacgcc agtggcggaa tatcccttaa
     3661 tgatgtagcg tgctacaccc acaataacga cgactccgat aaggagctct ataactgtta
     3721 gcattgtttc ccctgtctta tcgacaccca gagtaaaaat aagaaccaca aaagtggtat
     3781 aaaaatgtac cgaataaagg atggcgcctt actgattaaa atcacggcgc ggttattttt
     3841 tcatgtcatc actaaagatg aaatatgttt atacaaatt
//
LOCUS       DAJVBX010000276         3851 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.276, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000276 DAJVBX010000000
VERSION     DAJVBX010000276.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3851
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.276"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            45..1706
                     /gene="recN"
                     /locus_tag="OPV72_004241"
     CDS             45..1706
                     /gene="recN"
                     /locus_tag="OPV72_004241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HCR9916381.1"
                     /translation="MLAQLTISNFAIVRELEIDFQSGMTVITGETGAGKSIAIDALGL
                     CLGGRAEADMVRTGATRADLCARFALKDTPAALRWLEENQLEEGRECLLRRVISSDGR
                     SRGFINGTAVPLSQLRELGQLLIQIHGQHTHQQLTKPEQQKSLLDSYANEAALAQQMA
                     AHYQLWHQSCRDLAHHQQQSQERAARAELLQYQLKELNDFNPQAGEFEQIDEEYKRLA
                     NSGQLLTTSQNALALLADGEDVNLQSQLYSAKQLVSELVGMDSKLSGILDMLEEATIQ
                     LTEASDELRHYCERLDLDPNRLFELEQRIAKQISLARKHHVSPEALPQLYQSLLEEQQ
                     QLDDQADSLETLTLAVNKHHQQALETAQALHQQRQFYAQELGQLITESMHLLSMPHGL
                     FTIDVKFDEHHLSNDGADRVEFKVTTNPGQPLQPIAKVASGGELSRIALAIQVITARK
                     METPALIFDEVDVGISGPTAAVVGKLLRQLGESTQVMCVTHLPQVAGCGHQHFFVSKE
                     TDGAMTETHMQPLDKRARLQELARLLGGSEVTRNTLANAKELLAA"
     gene            1855..2193
                     /gene="bamE"
                     /locus_tag="OPV72_004242"
     CDS             1855..2193
                     /gene="bamE"
                     /locus_tag="OPV72_004242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamE"
                     /protein_id="HCR9916382.1"
                     /translation="MRCKTLTAAAAVLLMLTAGCSTLERVVYRPDINQGNYLTPTDVA
                     KVRVGMTQQQVAYALGTPMMTDPFGTNTWFYVFRQQPGHENVTQQTLTLTFNSSGVLT
                     NIDNKPALTK"
     gene            complement(2359..2649)
                     /locus_tag="OPV72_004243"
     CDS             complement(2359..2649)
                     /locus_tag="OPV72_004243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfH family protein"
                     /protein_id="HCR9916383.1"
                     /translation="MPDKLVVEVAYALPEKQYLQRVTLEEGATVEEAIRASGLLELRT
                     DIDLAKNKVGIYSRPVKLTDTVQDGDRVEIYRPLIADPKALRRQRAEKSAGR"
     gene            complement(2639..3076)
                     /locus_tag="OPV72_004244"
     CDS             complement(2639..3076)
                     /locus_tag="OPV72_004244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001543334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RatA family
                     toxin"
                     /protein_id="HCR9916384.1"
                     /translation="MPQISRTALVPYSAEQMYQLVNDVQSYPQFLPGCVGSRVLESSP
                     AQMTAAVDVSKAGISKTFTTRNQLTRNQSILMHLVDGPFKKLIGGWKFTPLSPEACRI
                     EFQLDFEFTNKLIELAFGRIFKELASNMVQAFTVRAKEVYRAG"
     gene            3265..3747
                     /gene="smpB"
                     /locus_tag="OPV72_004245"
     CDS             3265..3747
                     /gene="smpB"
                     /locus_tag="OPV72_004245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HCR9916385.1"
                     /translation="MTKKKAHKPGSATIALNKRARHEYFIEEEFEAGLALQGWEVKSL
                     RAGKANIGDSYVILKDGEAWLFGANFTPMAVASTHVVCDPTRTRKLLLNQRELDSLYG
                     RINREGYTVVALSLYWKNAWCKVKIGVAKGKKQHDKRSDLKEREWQLDKARIMKNAGR
                     "
BASE COUNT          997 a         1012 c          963 g          879 t
ORIGIN      
        1 ctgtatttaa ttacagtcat ggtttttcat acaggaaaac agctatgttg gcgcaactga
       61 ccatcagcaa ttttgctatc gttcgtgagc ttgagatcga ttttcagagc ggaatgaccg
      121 tcattactgg tgaaaccggc gcgggtaaat ctattgcgat tgatgccctg ggtctgtgtc
      181 tgggcggtcg cgctgaggcc gatatggtcc gtaccggagc gacccgcgcc gatttgtgtg
      241 cccgctttgc gctgaaagac acgcctgcgg cattgcgctg gctggaagaa aaccagcttg
      301 aagaaggtcg cgaatgctta cttcgccgcg ttatcagcag cgatggccgc tcacggggct
      361 ttattaacgg caccgctgtg cccctatctc aattgcgcga gctcggtcag ttgctgattc
      421 aaattcatgg tcaacatacg caccagcagc tgaccaaacc cgaacagcaa aaatcgctgc
      481 tggatagcta tgccaacgaa gccgctttag cgcagcagat ggctgcccac taccaattat
      541 ggcatcaaag ctgccgcgat ctcgcccatc accagcaaca aagtcaggaa cgcgccgcgc
      601 gcgcggaact gctgcaatat cagttaaaag agttgaacga ctttaatccg caggccggcg
      661 aattcgagca aattgacgaa gagtacaaac ggctggccaa cagcgggcag ttgcttacga
      721 ccagccagaa cgctctggcg ctactcgcgg acggcgaaga cgttaacctg caaagccagt
      781 tatatagcgc aaaacaactg gttagcgagc tggtgggtat ggacagcaag ctttccggca
      841 tcctggatat gctggaagaa gccactatcc aactcaccga agccagcgat gaattacgcc
      901 actattgcga gcgtctggat ttagacccca atcgcctgtt tgagcttgaa cagcgcatcg
      961 ctaaacaaat ttcgctggcg cgaaaacatc acgtcagccc ggaagcgctg ccgcagcttt
     1021 atcagtcact gctcgaagaa cagcagcagc tcgacgatca ggccgattcg ctggaaacgc
     1081 tgacgctggc ggttaataag catcaccaac aagcgctgga aacggcgcaa gcgctgcatc
     1141 aacagcgtca gttttacgcc caggagctgg ggcagttgat cactgaaagt atgcatttac
     1201 tttcgatgcc gcacggtctg tttactatcg acgtgaaatt tgatgagcat catctgagca
     1261 acgacggcgc cgatcgcgtg gagtttaaag tgacgacaaa cccgggtcag ccgctgcagc
     1321 ctatcgctaa agtcgcgtct ggcggtgaac tgtcgcgcat tgcgctggct attcaggtga
     1381 ttaccgcgcg caaaatggaa acgccggcgc taatttttga cgaggttgat gttggcatca
     1441 gcggcccaac cgccgccgtg gtcggtaaac tcctgcgtca gcttggcgaa tccactcagg
     1501 tgatgtgcgt cactcaccta ccacaggtag ccgggtgcgg tcaccagcac ttctttgtca
     1561 gtaaagaaac agacggggca atgaccgaaa cccatatgca acctttggat aaacgtgcgc
     1621 gtttacagga actggcccgc ctgttgggag gaagtgaagt tacgcgtaat acgctggcaa
     1681 acgcaaaaga actgctggcg gcgtaaactt ttttatctcc cgaaggtctg agttcacaac
     1741 aaaaacgccg taagacccga cagcaaaagg ttttaaagtg atgaaaggtc tattatcatc
     1801 ggcatattaa tatgagccac gtactgctca ggcccgaaaa ggaacccaat cactatgcgc
     1861 tgtaaaacgc tgactgctgc cgcagcagta ctcctgatgt tgaccgcagg ctgttccact
     1921 ctggagcgag tggtttaccg acctgacatc aatcagggga actatcttac acctacggat
     1981 gtcgccaaag tgcgtgttgg tatgacgcaa caacaggttg cgtatgcttt aggcacgccg
     2041 atgatgaccg atccttttgg tacgaacacc tggttttatg tcttccgcca gcagccagga
     2101 catgagaacg tgacgcagca gactctgacg ctcaccttta acagcagcgg cgtgttaacc
     2161 aatattgata acaaaccggc gttgacgaag taattttgtg ataccgcctg atgaggttac
     2221 gttcatcagg cctgcaaacc tctcccccgc catttggtac gaatttgcct gatggcgcta
     2281 cgtttatctg gcttacaggc acgcctgtgc ttcaggtgtg gtacggcttt cacaccgtta
     2341 tccggcaaaa gaggctaatt atctgccagc cgatttttcg gcacgctggc ggcgtaatgc
     2401 ttttggatcg gcgattaagg gacggtaaat ttcaacccga tcgccatcct gcaccgtatc
     2461 ggtgagtttt accggacgac tgtagatacc tactttattt ttcgccagat cgatatccgt
     2521 gcgcaattcc agcaagccgg aagcgcgaat cgcctcttcg accgtcgcgc cctcctccag
     2581 cgttacgcgc tgcaaatact gcttttccgg cagcgcataa gccacttcaa ccacaagttt
     2641 atccggcacg gtaaacctct ttggcgcgaa ccgtaaacgc ctgcaccatg ttggacgcta
     2701 actctttgaa tatacgacca aacgccagct caatgagttt attggtaaac tcaaaatcaa
     2761 gctgaaactc aatgcggcac gcctcggggc tgagcggggt aaatttccag ccgccgatca
     2821 gctttttaaa ggggccatcc accagatgca tcagaatact ctggttacgc gttagctgat
     2881 tacgcgtcgt aaacgtcttg ctgatacccg ccttcgacac gtcaacagcc gccgtcatct
     2941 gtgctggcga tgactccagg acacgactgc caacacaccc aggcaaaaac tggggatacg
     3001 attgcacgtc attcactaac tgatacatct gttccgcact gtaggggact aaagcagtcc
     3061 gactaatctg aggcatagca attcccatca acataaatcg tgtaaataat accacttatc
     3121 agcgagtaaa aaaaatgctg tccccaaccg tcatgcctta attgtgcgtg catagcccaa
     3181 ctcatgctaa gatagatttt tgcacctcat caggacgtaa tggggtgttt tcgatatcag
     3241 attacctatg aattcacgac acttatgacg aagaaaaaag cacataaacc gggctcagcc
     3301 accatcgcgc tgaataagcg cgcccggcac gaatacttta tcgaagaaga gttcgaggct
     3361 ggtctcgccc tgcaaggctg ggaagtaaaa tctctgcgcg caggaaaagc caatatcggc
     3421 gacagttacg ttatcctcaa agatggcgag gcctggctgt ttggcgcaaa ctttacgccg
     3481 atggcggtcg cctcgacaca tgtcgtatgc gacccaaccc gaacccgcaa actgttgtta
     3541 aatcagcgtg agcttgattc gctgtatggc cgtattaatc gtgaaggtta tactgtcgtc
     3601 gcgctttctc tgtactggaa aaatgcctgg tgcaaagtga agatcggcgt ggcgaaaggt
     3661 aaaaaacaac atgataaacg ttccgatctt aaagaacgtg agtggcaact ggataaagca
     3721 cgcattatga aaaatgcagg ccgataatag acattttttg tgaccagctt ctcagtatga
     3781 agctggtcaa tgttcatatc tcatgcatgc ctcgaaaata tattctctgt gtctgacgct
     3841 tatcaatagc a
//
LOCUS       DAJVBX010000277         3833 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.277, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000277 DAJVBX010000000
VERSION     DAJVBX010000277.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3833)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3833)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3833
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.277"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..2864)
                     /locus_tag="OPV72_004246"
     CDS             complement(<1..2864)
                     /locus_tag="OPV72_004246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001751376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HCR9916386.1"
                     /translation="MKLHFESDLTYQQNAITSVCDLFEGQEKWESEMTVLAPAQGALS
                     FEGATGSMPVNPQIPEDDVLLKNLNNVQLKNQLPPSPVLDSHDFTVEMETGTGKTYVY
                     LRTMLELNKRYGMSKFIIVVPSVAIKEGVYKTLQITEEHFKSLFAGVPYEYYLYDSAK
                     PADVRNFATSSVMQIMVMTVGAINKKDVNKLYQSSEKTTVDDLDKPIDLIRATRPIII
                     VDEPQSVDGGLNGAGKTALDAMHPMFTLRYSATHVHKHHMVYRLDAIDAYNQKLVKQI
                     EVAGLEVQNASNSPYVKLVSINNKKNSISATVIVDIADKKGNVNRSEITVYDGMTLDD
                     ETGRDIYQGYRISEIRTGKEGYLTLETPSDTYYMKVGDVVGDIDPMLIQRHMIRRTIR
                     EHLDKELRLNTQQIKVLTLFFIDKVDLYRQTNEEGVREPGEYARIFEEEYLKAIKSPA
                     YKDLLPSHPEHAKDVHDGYFSIDKKGAWAETSESNNTGRENAERGYNLIMKNKEKLLS
                     FSNPVRFIFSHSALKEGWDNPNVFQICSLREMGSERERRQTLGRGLRLCVNQEGERVR
                     DDSINILTVVASENYEAYAERLQSEIESETGIRFGVIEKDAFAHLIFADSSQGLGISG
                     SHDIWSELQTEGYIEKSGKITKTLKKELFENTFVVSEKYASLQEQIETILRKSAGRLN
                     INNADERKTIKYRKEVLNSPEFEALWQRICQKTLYRLAFDEEELIKSCTKSLSEMQPV
                     AKAMVSFSKATIKQSQSGLDVKALSNGTTSSVVDVAEQPLPDILGVLQEKTGLTRRSL
                     STILKESGRLADFAKNPQQFISEAIGRINYCKRLSIVDGIKYYPLKGEVYAQSLFMDK
                     ELTGYARNLFETSSKSVYEYVPKDSEVESRFAQELEEQDEVKLYVKLPGWFKIPTPLG
                     TYNPDWALVIEDNGEEHIYFVVETKSKHIGLGHEEDAKIA"
     gene            complement(2874..3716)
                     /locus_tag="OPV72_004247"
                     /pseudo
     CDS             complement(2874..3716)
                     /locus_tag="OPV72_004247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239317.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
BASE COUNT         1015 a          835 c          738 g         1245 t
ORIGIN      
        1 caggctatct tcgcatcttc ttcatgacca agaccaatgt gtttactttt tgtctctaca
       61 acaaagtaaa tatgttcttc accattgtct tcaataacta acgcccagtc aggattgtag
      121 gttcccagtg gcgtcgggat tttaaaccat cccggcagct tcacataaag cttaacttca
      181 tcctgttctt cgagttcctg agcgaaacgg ctttcgactt cagaatcttt aggaacgtat
      241 tcgtaaactg acttagacga ggtttcaaaa agattacggg catatcctgt tagctcttta
      301 tccataaaga gactttgcgc atacacctct ccttttagtg gataatattt aataccatca
      361 acaattgaca ggcgtttgca gtagttgatt cggcctatag cttcactgat aaactgctgt
      421 ggatttttag caaaatcagc gagtcttcca ctctctttca ggatggtgct taaactgcgt
      481 cttgtcagtc cggttttttc ctgtagaaca ccaagaatat ctggcaatgg ctgctctgca
      541 acatcaacta cagagcttgt tgttccatta gacagagctt taacatcaag gccagattga
      601 ctttgtttga ttgttgcttt gctgaaactg accattgctt ttgctacagg ctgcatttca
      661 gaaagtgatt tcgtacagga tttgatcaat tcttcttcat caaatgctag ccgatacagc
      721 gttttttgac aaatgcgctg ccataacgct tcgaattccg ggctgtttaa gacttctttc
      781 cggtatttga ttgttttacg ttcatcagca ttgtttatat tgagtcgccc tgctgattta
      841 cgcaggatag tttcaatttg ttcctgtagt gaggcatact tctcactaac aacaaaagtg
      901 ttttcgaata attctttttt cagggttttg gtaatttttc ccgatttttc aatataacct
      961 tcagtctgaa gttcagacca gatatcatgt gaaccggaaa tacctaaacc ttgtgaggaa
     1021 tcagcgaaga taagatgggc gaacgcatct ttttcaatca caccaaaacg tatgcctgtt
     1081 tcgctctcaa tttcagactg taatcgttca gcgtaggctt cataattttc actggcaacg
     1141 actgtcagaa tgttaatgct gtcatcacga acacgttcac cctcttggtt aacacacagg
     1201 cgaagaccac ggcctaatgt ttgacgacgt tctcgttcac ttcccatctc tcggaggcta
     1261 cagatctgga atacattggg gttatcccag ccttctttca aagcagagtg cgaaaaaata
     1321 aacctcactg gattcgagaa actcaaaagc ttctctttat ttttcataat gagattataa
     1381 ccacgctcag cattttcacg gcctgtatta ttgctttcgc ttgtttcagc ccatgcacct
     1441 tttttatcaa tggagaaata accatcatga acatctttgg catgttctgg atgagaagga
     1501 agtaaatctt tataggcagg gcttttgatt gctttaagat attcttcttc aaagatacgg
     1561 gcatattcac ccggttcacg tactccttct tcattggtct gacgatataa atcaacctta
     1621 tcaatgaaaa acagggtaag aaccttgatt tgctgagtat tcaggcgaag ttctttatcc
     1681 agatgttcac ggattgtacg tctgatcata tgacgctgga tgagcatagg gtcaatatcc
     1741 cccacgacat caccgacttt catatagtag gtatcagaag gtgtttccag tgtaagataa
     1801 ccctctttgc cagttcggat ctcgcttatc cggtaaccct gataaatatc acgtcctgtt
     1861 tcgtcatcga gtgtcatacc gtcatatacg gtaatctctg aacgatttac gttccctttt
     1921 ttatcggcta tatcaacaat aacagtcgca ctaatgctat tcttcttatt gttaatactg
     1981 accagtttta cataggggct attacttgca ttttggactt caagcccggc aacctcgatc
     2041 tgtttgacca gtttttggtt gtaagcatca atggcgtcaa ggcggtacac catatgatgt
     2101 ttatgaacat gtgttgctga atagcgtaag gtgaacatgg ggtgcatagc atcaagtgcg
     2161 gttttacccg caccgttcaa gccaccatca acactttgcg gttcatcgac aataataatt
     2221 ggacgtgtag cacggattaa atcaatgggc ttatccagat cgtccacagt tgttttttca
     2281 ctggactgat agagcttgtt aacatctttt ttgttaatcg cacccacagt cattaccatg
     2341 atctgcataa cagaactggt tgcaaaattt cgaacatccg caggttttgc cgaatcatac
     2401 agatagtatt cgtatggaac tcccgcaaac aggcttttaa aatgttcttc agttatttgt
     2461 agtgttttat aaacgccttc cttgatagca actgaaggaa ccacaataat aaatttactc
     2521 atgccatagc gtttattcag ctccagcatg gtgcgaagat aaacatacgt tttacctgtc
     2581 cctgtttcca tttcgacagt aaaatcatgg ctgtcgagca caggtgaagg tggaagctgg
     2641 ttttttaact gaacattgtt cagattttta agcagtacat catcttcggg tatttgtggg
     2701 ttaacaggca ttgaacctgt tgcgccttca aatgagagtg caccctgagc tggggccagc
     2761 acagtcattt cgctttccca tttctcttgc ccttcaaaca aatcacagac cgatgttatg
     2821 gcgttttgct gataggtaag gtcagattca aaatgtagtt tcatctcatt cccttacagg
     2881 ctgtgcaggt tagtcaggcc atgttgttcc agaatggcgc aaagatttgt tttagcaacg
     2941 ttattttcaa atgcgtcatc aaggaaatag cagaccgtat ctttgccagc ttttaaactc
     3001 ttataccagt cgatgatccc cttggtcagt tcttctactg aagatgcagg gatttgttta
     3061 gcaaagcagg taaacaattt gccaccgtca acacaagaaa cggttaatcc atcaaactga
     3121 cgggtttcaa tgtttacact caggtcaatg ccacgtttga gcatcaactc tgtgagcaga
     3181 tcttcttcat tacggccttc aaggattggg cttacatagg catcaatctg ttctgaaagg
     3241 gtttctgctg tggcttccca cggacggata ttagatgtat cgagtttgaa aacacgaaaa
     3301 ccaacatcac cattccagtc aggattatct tcacgaacct ttttacctgc acggcgtagg
     3361 cgctcttttg tgatttctga tatttttaaa gacattccat gcttcttcaa aaaagctgct
     3421 gcaatggctt gttccttagt gttttcgtca actaattctg gtagttgcgc aatcacaaat
     3481 ttgattttcc tattcttaat tgcattggct gtgaaaacag cgtgaccaaa agttcctgaa
     3541 ccgccaaaaa aatcaagtgc tatgcattcc tcattagggt aagtagctat ttctattatg
     3601 cgaagaagag tgcctaaagg ttttggtcta gaaaaaactt ctttgtcgaa tccaatttca
     3661 ataaattgtt cacttcctct ttcactattt acgtctctat gtgtccatga ggaggtggct
     3721 tttaccgcat cccttttgga tagatagtct ttctccatga tgccccacat ttttttagta
     3781 ggcataaatt tagcgtatac actctcgatt tttgtttttg ctgtatcaaa tcc
//
LOCUS       DAJVBX010000278         3812 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.278, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000278 DAJVBX010000000
VERSION     DAJVBX010000278.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3812
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.278"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            222..347
                     /locus_tag="OPV72_004248"
     CDS             222..347
                     /locus_tag="OPV72_004248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001748351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCR9916387.1"
                     /translation="MKKWLIGGILIASFLTGCLMWHNIDKWFNKDIEVFYAGDDN"
     gene            547..774
                     /locus_tag="OPV72_004249"
     CDS             547..774
                     /locus_tag="OPV72_004249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916388.1"
                     /translation="MLLVGLPPVAEKDNDDVTVAETDEYDDREFYFWRPYFLPKGRPK
                     AALGLIMEKGVGHCHNQPVYTNVIDNHYQLW"
     gene            972..1439
                     /locus_tag="OPV72_004250"
     CDS             972..1439
                     /locus_tag="OPV72_004250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20 family protein"
                     /protein_id="HCR9916389.1"
                     /translation="MALRTLSALPVFADSLFSDRFNRIDRLFSQLTGDTPVAATPAYD
                     LQKRDANNYLLTVSVPGWKEEELEIETVGGNLNITGKHTEETVEDQTHWIYRGIRKAD
                     FQLSFSLPEHAKVNNAKLEQGLLLVEIYQEIPESEKPKKIAIESKPKAIEHKS"
     gene            1778..2821
                     /locus_tag="OPV72_004251"
     CDS             1778..2821
                     /locus_tag="OPV72_004251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exo-alpha-sialidase"
                     /protein_id="HCR9916390.1"
                     /translation="MKLALVNRQVILPESGTESFQCHASTLVRLPCGTLVAAWFAGLC
                     EGSEDTAIWLSRYEHNIWTTPQRVAAREGEAHWNPVLFYPSDKLWLFYKVGSGVHVWK
                     TWFITSSDRGFTWSTPAPLVNDDILPRGPVKNKLLLASNGAWIAPGSIESPERWRAFV
                     DRSSDEGKHWNISFVPLEPDNAISGTNVALWDGVKKGMLWECCLENLLRWDGVIQPTL
                     WESSPGHIHMLLRSTRGAIFRSDSIDYGATWSVARATFLPNNNSGIDLVSMQDGTLIL
                     ALNPVNGNWGKRYPLSLIASQDNGESWLPLLDLESDHGEYSYPAIISKGGVVHITYTW
                     NRKNIVYCRLQTV"
     gene            complement(2904..3434)
                     /locus_tag="OPV72_004252"
     CDS             complement(2904..3434)
                     /locus_tag="OPV72_004252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b"
                     /protein_id="HCR9916391.1"
                     /translation="MAHFSRLQITLHWLTLLLTGIAYAAIELRGWAPKGSSVYLFMKD
                     MHYDMGVLVWALMFLRLYLKHKYPDPVITPPPPHWQHVAAKLMHIALYLTFLALPLLG
                     VAMMASGGKSWSFFGFTVPVFLTPDSTLKSDIKRIHEMLANIGYFLIAMHAAAALFHH
                     YIQKDDTFSRMLPGKS"
     gene            complement(3583..3783)
                     /locus_tag="OPV72_004253"
     CDS             complement(3583..3783)
                     /locus_tag="OPV72_004253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002444038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRL-like family protein"
                     /protein_id="HCR9916392.1"
                     /translation="MTATSLPATKTGKACAQTVLGIVNTGDASIDSAKKAGDISLVSS
                     VDYETTGSYPFYGKTCVVVRGQ"
BASE COUNT         1045 a          812 c          933 g         1022 t
ORIGIN      
        1 agacaaatct taaaatcata aactatagac tgcaaatcat tatggcgcga tggaaaatga
       61 ttgtcaccac tgctcaatac tatggcataa aaaccgaaga aaacggtact gttcactgtc
      121 tcgtttcata cggtatctgt cagtgaaact atttcttcaa atgatggtct ttttattatc
      181 gatcagataa tggcatcaac aggggttatt taggagtata tgtgaaaaag tggcttatag
      241 gagggatatt gatcgcaagt tttctgaccg gttgtctgat gtggcacaac attgataaat
      301 ggtttaataa agatatcgaa gttttctacg ccggagacga taactaaaac tcctgtcagt
      361 tggcaacggg tgtcatatct tcaggtatgg cgcccggagc agccgggcgc aaattgtagg
      421 tgtataaaag tcatttcatt aaaattttag cgacaacatg gacagtcact accgcgtgct
      481 aacggccctc tgaagtcaca agatgaataa gccagttttt tgtttcagcg gtgactgaaa
      541 catattttgc tcctggtggg cttaccgcca gttgctgaaa aagacaacga tgatgtaact
      601 gttgcagaga ctgacgaata cgacgaccgt gagttttatt tttggcgacc atatttcctc
      661 ccaaaaggcc gcccgaaggc ggcgctgggt ttgataatgg agaagggcgt tggtcactgc
      721 cataaccaac ctgtatacac taatgtaatt gataatcatt atcaattgtg gtgatgaaga
      781 aaaattgtaa agatgaaggg acagcggaaa tggcaatgaa cgggatgaga tttttcgtta
      841 accacttaaa ttcgtgacta aaaaaagtct tttataggct tgaaaatgtt ttttccgtcc
      901 ctatgtagtc agtggacaag caatgcttgc cttgatgttg aacttttgaa tagtgattca
      961 ggaggttaat gatggcactc agaaccttgt cagcacttcc cgtgtttgct gattctcttt
     1021 tctctgaccg tttcaaccgt attgatagac ttttcagtca attaacagga gatacgccag
     1081 tcgctgcgac gccagcttac gatctgcaaa agcgcgatgc gaataactat ctgcttaccg
     1141 tgagcgttcc tggctggaaa gaggaagagc ttgaaattga aacggttggc ggcaacctga
     1201 atattacggg taaacacact gaagagacgg tagaggatca gacgcactgg atttatcgtg
     1261 gtattcgtaa ggcagatttc cagttgagtt tttctttgcc tgaacatgct aaggtgaata
     1321 atgcaaaact ggaacagggc ctcttgttgg tagagattta ccaggaaatc cctgaaagcg
     1381 agaaaccgaa aaaaattgcc atagaaagca aaccaaaggc gattgaacat aaatcataaa
     1441 agcattaatg gaggcccgtt tagacgggcc ttcattgtct gtagcgaaaa gtatcccgtc
     1501 atgcttgtag gcacagatcg ctaaatatta tagccctgac ctctatatta tcccgtgcca
     1561 ctgacctcgt cgccattgga cggcggtaag ttggaattat ccgcgaggtc agtccaattt
     1621 ttgtccactc tcgacattct gcctgttatg ggcgcgatac ctgaacataa attcgtatag
     1681 cggttgatcg ttttcaccgc gttgatgcta tttctgctaa cactactttc atacgtaaaa
     1741 aagctgatgc tttttacctt atttaataga ggcaggtatg aaattagcgc tcgtcaatcg
     1801 acaggtcatt ttaccggaaa gcggaaccga gtccttccag tgccatgcct ctacgcttgt
     1861 tcgcctaccg tgcggtacgc tcgtggccgc atggttcgcg gggttgtgcg aaggaagcga
     1921 agatacagcc atctggctat ctcgctatga acataatatc tggacaacac cgcagcgagt
     1981 ggcggcacgc gagggggaag cgcactggaa tccggtgtta ttttacccgt cggataaatt
     2041 gtggttattt tataaagtag gcagcggcgt acacgtgtgg aaaacctggt ttatcacctc
     2101 cagcgatcga ggatttacct ggagtacgcc agctccgttg gttaacgatg atattttgcc
     2161 gcgcggtccc gtaaaaaata aactcctgct ggcatcaaat ggcgcctgga ttgcgccagg
     2221 gtcgattgaa agtcctgaac ggtggagggc atttgtggat cgatcctctg acgaaggaaa
     2281 acactggaat atctcttttg ttccgctgga gcctgataac gctatttccg ggacaaacgt
     2341 agcgttgtgg gatggtgtaa aaaaggggat gttgtgggaa tgttgtctgg aaaacctcct
     2401 gcgctgggat ggcgttattc agcctacgct gtgggagtct tctccggggc atatccatat
     2461 gttgttacga agcacacgcg gggcaatttt tcgcagtgat tcaatcgact atggcgctac
     2521 ctggtctgtt gcccgcgcga catttttacc gaataataat agtggtatcg atctggttag
     2581 tatgcaggac ggtacgctga ttcttgcgtt aaatccggtc aacggcaact ggggaaagcg
     2641 ctatccgctt tcactgattg cttcccagga taatggcgaa tcatggctac cgctactgga
     2701 cctggaaagt gaccacggtg agtattctta tcccgctatt attagcaagg gcggcgtcgt
     2761 acatatcacc tacacgtgga accggaaaaa tatcgtatat tgtcgattac aaacggtata
     2821 aggcgctatc agtcgaaacc gatagcgctg gaataataat gccttgcccg gcgtgctctc
     2881 tcacgtcggg atggccgaaa tagtcatgat ttaccgggta acatccttga aaatgtatcg
     2941 tctttttgta tgtaatggtg aaacaacgcc gctgctgcat gcatggcaat caggaaatag
     3001 ccgatattgg ccagcatttc atgaatacgc tttatatccg attttagggt gctatctggc
     3061 gtcaaaaata ccggtacagt aaaaccaaaa aagctccagc ttttcccgcc tgatgccatc
     3121 atcgcgacgc ccagcagcgg taaggcgaga aaagtgagat aaagcgcgat atgcattaat
     3181 ttagcggcta cgtgctgcca gtgaggaggg ggaggcgtaa tgaccggatc cgggtatttg
     3241 tgtttaagat ataaccgtaa aaacatcagc gcccagacca gaacgcccat gtcatagtgc
     3301 atgtctttca taaataggta aacgctggag ccttttggcg cccacccccg taactcaata
     3361 gccgcatatg ctatgcctgt caggagcagt gttaaccagt gaagcgttat ttgcagtctt
     3421 gagaaatgtg ccattattat tatcctttat taacaactgc ttgtagggta tgcgtaaaat
     3481 cttaacagaa ccttaaagcg ggggctgagt cgcaaggaac agacagagat agcggcacgt
     3541 aaaatgggat aaaaagccgg cggcatcgcc ggcttactgt tgttattgtc ctcttacgac
     3601 aacacaggtt ttaccataaa acggatatga gcctgtagtt tcataatcaa cactcgacac
     3661 taaagaaata tcgcccgctt ttttcgctga atcaatagat gcgtcgccgg tatttacaat
     3721 acccaatacc gtttgcgcac acgctttacc ggttttggtt gccgggagac tcgtggcagt
     3781 aattggccct ttaacatccg tatataagcc aa
//
LOCUS       DAJVBX010000279         3761 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.279, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000279 DAJVBX010000000
VERSION     DAJVBX010000279.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3761
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.279"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            5..1984
                     /locus_tag="OPV72_004254"
     CDS             5..1984
                     /locus_tag="OPV72_004254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020078314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCR9916393.1"
                     /translation="MRLKSIVKSFALAGLLSSTALTPLFAQEAPKGATASTKQANNAL
                     YNQLPFSDNTDFTNAHKGFIADLPAEVIKGEQGNVIWNPQQYAFIKEGEKSPDTVNPS
                     LWRQSQLINISGLFEVTDGVYQIRNLDLSNMTIIEGKEGITVVDPLVSAETAKAGMDL
                     YFKNRGNKPVVAIIYTHSHVDHYGGVRGVVDEADVKSGKVKVYAPAGFMEAAVAENIM
                     AGNVMSRRASYMYGNLLKPDASGQVGAGLGTTTSAGTVTLIAPTNIIDKDGQKEVIDG
                     LTYDFMLAPGSEAPSEMLWFIEEKKLIEAAEDVTHTLHNTYSLRGAKIREPLPWSKYI
                     NEAIVRWGDKAEIIMAQHHWPTWGNENVVGLLKSQRDLYRYINDQTLRMANEGLTRDE
                     IAANFKLPDSLAKTWANRGYYGSISHDVKATYVLYLGWFDGNPATLDELPPEEAAKKF
                     VEYMGGADAILQKAKADFDQGNYRWVAQVVSKVVFADPNNQNARNLEADALEQLGYQA
                     ESGPWRNFYLTGAQELRNGVVKGPTPNTASPDTVRAMTPEMFFDFLAVHINGEKAGNA
                     RAVFNIDLGSDGGKYKLELENGVLNHTANAEAKDADATITLNRDTLNKIILKEETLKQ
                     AQDKGEVNVTGNAAKLDEMLGYMDKFEFWFNIVTP"
     gene            complement(2393..3007)
                     /locus_tag="OPV72_004255"
     CDS             complement(2393..3007)
                     /locus_tag="OPV72_004255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="disulfide bond formation protein B"
                     /protein_id="HCR9916394.1"
                     /translation="MKTHHHPTTFVHLINQIGLLGICVALVVAFYYQLVRHELPCPIC
                     LLQRAGLIIAGFGFLFNLCFGLRGIHYGMVIIGSILTGVMASRQICLHIMPGDTGYGS
                     AFFGLHFYTWTLITSILIIIAVAVVLAISSMNAAFRSLNINPNLFSIVGWVFLLLITA
                     NLISTVLECGGGECAANPVTYKLLSKQDIAFLKTGLLTRTVLRL"
     gene            complement(3017..3175)
                     /locus_tag="OPV72_004256"
     CDS             complement(3017..3175)
                     /locus_tag="OPV72_004256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916395.1"
                     /translation="MFMFLPFLLALSVAMGAINRKDKVSYILWAVLLIVTILSFIHHM
                     TNSLTLSF"
     gene            complement(3308..>3761)
                     /locus_tag="OPV72_004257"
     CDS             complement(3308..>3761)
                     /locus_tag="OPV72_004257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HCR9916396.1"
                     /translation="ALISAVLIHAIIYTQCKKRSCTVSVITFNALPCLLAGLILSATG
                     WFFERPQVSTFSVHSILATLYLGAFAGVFGILCYFALQQKANAFQASLVFLIFPLIAV
                     SLEDYIYGYAISTHSMLLIIPLAIGIFLTLVARNIPVTSRCRDNSSQK"
BASE COUNT         1097 a          823 c          885 g          956 t
ORIGIN      
        1 acaaatgaga cttaagtcga tcgttaaaag ttttgcgctg gcggggctac tctcttccac
       61 tgcgctgaca cctttatttg cccaggaagc cccaaaaggt gccactgctt caaccaagca
      121 agctaacaat gcgctttata accaacttcc tttctctgat aacaccgatt tcacgaatgc
      181 ccataaaggc tttattgctg atttacctgc agaggtgatt aagggagagc aagggaatgt
      241 catctggaat ccacagcagt acgctttcat aaaagaaggg gaaaaatctc ctgacactgt
      301 taaccctagt ctgtggcgtc agtcccaact aatcaatatc agtggcttgt ttgaagtaac
      361 agacggcgtc taccagattc gtaaccttga tttatccaac atgacgatta tcgaaggtaa
      421 agaggggatt acggttgtcg atccgctggt ttctgcggaa acagccaaag ccggtatgga
      481 tttgtatttc aaaaaccgtg gcaataagcc tgttgtcgcc atcatttata ctcatagcca
      541 tgttgaccac tatggtggtg tgcgtggcgt tgtcgatgaa gcggacgtga aatccggcaa
      601 ggtgaaagtg tatgcgcctg ctggctttat ggaggcagca gtagccgaga atattatggc
      661 cggcaacgtg atgagccgcc gtgccagcta tatgtatggc aacctcctga aaccagatgc
      721 ctccggccag gttggcgccg gactggggac gaccacctct gcggggacgg tgacactgat
      781 tgcgcccact aatatcattg ataaagacgg ccagaaagaa gtgattgatg gcctgactta
      841 cgactttatg ctggcccctg gttcggaagc cccttcggaa atgctgtggt tcatcgaaga
      901 gaagaaactc atcgaagccg cagaggacgt cactcacacc ctgcataaca cttactcgct
      961 acgcggcgca aaaattcgtg agccgttgcc gtggtcgaaa tatatcaacg aagctatagt
     1021 gcgttggggt gacaaagctg aaattattat ggcccagcac cactggccga cttggggtaa
     1081 cgagaatgtt gttggtctgc tgaaaagcca gcgagacctg tatcgttata tcaatgacca
     1141 gactctgcgt atggccaatg aaggtctgac tcgcgacgaa atagcggcca acttcaaact
     1201 accggatagc ctggcaaaaa cctgggccaa ccgcggctat tacggctcca tcagccatga
     1261 cgtaaaagca acgtatgtgc tgtatctcgg ttggttcgat ggcaatccgg caacccttga
     1321 tgagctgcca cccgaagaag cggctaagaa atttgttgaa tatatgggcg gtgccgatgc
     1381 gattcttcag aaagccaaag cagactttga ccaggggaac taccgttggg ttgctcaggt
     1441 ggtgagtaag gtcgtgtttg ccgatccaaa taaccagaat gcacgtaacc ttgaagccga
     1501 tgcgttggaa caattggggt atcaggctga atctggtcca tggcgtaact tctacctgac
     1561 cggtgcgcag gagctgcgta acggtgtggt taaaggtccg acgccaaata cagcaagtcc
     1621 ggataccgtt cgggcaatga cccctgaaat gttcttcgat ttcctggctg tacatatcaa
     1681 cggtgaaaaa gcgggtaatg cccgggcggt gtttaatatt gaccttggca gcgacggcgg
     1741 aaagtacaag cttgagctgg aaaatggcgt gctgaaccac acggctaatg ctgaagcgaa
     1801 agacgctgat gccacgatta ctctgaaccg tgacacgctg aataaaatta tcctgaagga
     1861 agaaactctg aagcaggctc aagataaagg agaagtcaac gttaccggta atgctgcgaa
     1921 actggatgag atgctgggct atatggacaa gtttgagttc tggttcaata tagttacacc
     1981 ataaatagat tccctgcggc gtcaatgctg cagggaagtt acttcagaca attctgtacg
     2041 tttttcatac tcgatttttc cttcattctt tatatcttgc ttcattttat gtatttgctg
     2101 ctgaagcaca tgaccctgat gccagtcagt cctgattctg ttatgcacag cctttttcat
     2161 cagatgacag taactggttg ttgcgtgatt caatggtctg cgagtctggt caacatgctt
     2221 ttagttagtt aaatgtgatt ctactaattc gtaatgcgaa ggttataagt ttgattccta
     2281 ttattgcacc atttcaacgt tactgaaact tccgtgttag cccataacca ttccagtttc
     2341 tacaagacag gtgcttgcta tatatttacc aatcagtcat tttaaaagtg cgtcataacc
     2401 ggagaactgt cctcgtcagg aggcctgttt tcagaaaggc aatatcctgc ttcgacagta
     2461 gcttatatgt gaccgggtta gcagcacatt cccctccgcc acattccagt acagttgaaa
     2521 taaggttggc agtaatcagt aatagaaata cccaaccgac aatactgaac aggttcggat
     2581 taatattcaa tgaacgaaat gcagcattca tgctactgat tgccagaact accgcaacag
     2641 caataataat gagaattgac gtaatcagag tccaggtata aaagtgtaat ccaaaaaatg
     2701 cagaaccata tcctgtgtca ccgggcatga tatgcaaaca tatttgccgg gatgccataa
     2761 ctccggtcag gatactgcca ataattacca tcccgtaatg tatgcctcgt agaccaaagc
     2821 agaggttaaa taaaaagcca aaaccggcga tgatgaggcc agcccgctgt aataagcaaa
     2881 ttggacaagg cagctcatgc ctaacgagtt gataataaaa ggctacaacc agagcaacgc
     2941 atatcccaag gagtcctatc tgattaatca gatgaacaaa tgttgttgga tgatgatgcg
     3001 ttttcataca cactccttaa aatgacaaag ttagcgaatt ggtcatatga tggatgaatg
     3061 ataaaatagt gacgatgagt aaaacggccc atagaatgta gctgacttta tcctttctgt
     3121 ttatggctcc cattgccacg ctcagtgcaa gcaagaatgg cagaaacatg aacataaaaa
     3181 actcctttat tacattgctt gttaatataa tcgctgtgta ttaccgggtc tgtattccag
     3241 cttatccacc ccgcattagc tggagctcag taaggcatca ggaattattt gcgttattat
     3301 aaatcgatta tttctgtgat gaattatccc gacatctgct ggttacaggg atatttctgg
     3361 cgacaagagt aagaaatatc ccgatagcta atggtataat aagcagcatt gagtgtgttg
     3421 aaatagcata tccataaata tagtcttcca gacttaccgc aatcagcgga aagataagaa
     3481 atacaagcga agcctggaag gcgttagcct tttgctgaag cgcaaagtag cacaggatac
     3541 caaaaactcc ggcaaaagcc ccgagataca gggtagctaa tattgagtgt actgagaagg
     3601 ttgatacttg tggtctttca aaaaaccatc ctgtcgcaga aagtatcaac ccagctaaaa
     3661 ggcacgggag cgcattaaat gtgataacag agacagtaca acttcttttc ttacattgtg
     3721 tatatattat ggcatggatt aacacagcag aaataagcgc a
//
LOCUS       DAJVBX010000280         3742 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.280, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000280 DAJVBX010000000
VERSION     DAJVBX010000280.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3742
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.280"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..616)
                     /locus_tag="OPV72_004258"
     CDS             complement(<1..616)
                     /locus_tag="OPV72_004258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001528503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916397.1"
                     /translation="MMKMSRTAIALSLLGMAAHPVCAAPSFEETARQVIIAFQQRDNA
                     KINALIDKKVGMYVLYRIGAGFDYKWMKKFDINKPIPDFNYLLGQVGWFSEHIPVDKE
                     FDHHTEVEYVCEKGWDHAGFFVSYTGSDNALLTFSMVNGADSGDQASDTRIANARRLE
                     LQSERVVAVPKEWGDGLIFHLSELHGLGKGWSLTLLDLVTEDCSA"
     gene            780..2141
                     /gene="yegQ"
                     /locus_tag="OPV72_004259"
     CDS             780..2141
                     /gene="yegQ"
                     /locus_tag="OPV72_004259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 5-hydroxyuridine modification protein YegQ"
                     /protein_id="HCR9916398.1"
                     /translation="MFKPELLSPAGTLKNMRYAFAYGADAVYAGQPRYSLRVRNNEFN
                     HENLQLGINEAHALGKKFYVVVNIAPHNAKLKTFIRDLKPVVEMGPDALIMSDPGLIM
                     LVREHFPAMPIHLSVQANAVNWATVKFWQQMGLTRVILSRELSLEEIEEIRQQVPDME
                     IEIFVHGALCMAYSGRCLLSGYINKRDPNQGTCTNACRWEYNVQEGKEDVVGNIVHKH
                     EPIPVQNVEPTLGIGAPTDKVFMIEEAQRPGEYMTAFEDEHGTYIMNSKDLRAIAHVE
                     RLTKMGVHSLKIEGRTKSFYYCARTAQVYRKAIDDAAAGKPFDPTLLETLEGLAHRGY
                     TEGFLRRHTHDDYQNYEYGYSVSERQQFVGEFTGERKGQLAAVAVKNKFSVGDSLELM
                     TPQGNINFTLEQMENAKGDAMPVAPGDGYTVWMPVPQDVTLDYALLMRNFSGESTRNP
                     HAK"
     gene            2593..2772
                     /locus_tag="OPV72_004260"
                     /pseudo
     CDS             2593..2772
                     /locus_tag="OPV72_004260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461081.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="non-LEE encoded effector protein NleB"
     gene            complement(2782..3198)
                     /locus_tag="OPV72_004261"
     CDS             complement(2782..3198)
                     /locus_tag="OPV72_004261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CesT family type III secretion system chaperone"
                     /protein_id="HCR9916399.1"
                     /translation="MYSRADRLLRQFSLKLNADSIAFDENRLCSFIIDNRYRILLTST
                     NSEYIMIYGFCGRPPDNNNLAFEFLNSNLWFAENNGPHLCYDNNSQSLLLALNFSLNE
                     SSVEKLECEIEVVIRSMENLYHILQDKGINLDTDYT"
     gene            complement(3320..3655)
                     /locus_tag="OPV72_004262"
     CDS             complement(3320..3655)
                     /locus_tag="OPV72_004262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916400.1"
                     /translation="MNVTSGVNAQTPLLPPSEWGDDEKPVAEIVEFNAYGNKPRCLMC
                     LGTTALFTGAFSGVCSGAVASVSSGAAYTTALTILGASFGMGGIGMMGICAGLYLSAN
                     GVRTRPAWP"
BASE COUNT         1007 a          992 c          800 g          943 t
ORIGIN      
        1 acgcactaca atcttccgtg accaaatcca gcagcgttaa actccaccct ttgcccaagc
       61 catgaagctc gctcagatga aaaatcaaac catcacccca ttctttcggc actgccacca
      121 ctcgctctga ttgcagctca agccgcctgg cgtttgctat acgggtatcc gacgcctgat
      181 ccccactatc cgctccattc accatgctaa acgtcagcag cgcattatca gaaccggtat
      241 agctgacaaa aaaaccggcg tgatcccatc ccttttcaca aacgtactca acctccgtgt
      301 ggtgatcaaa ttccttatcc acaggaatat gctctgaaaa ccaacctacc tgccccaaca
      361 ggtagttaaa gtcaggtatc ggtttattaa tatcaaattt tttcatccat ttataatcaa
      421 acccagcccc aattcggtac agcacataca tcccgacttt tttatcaatc agggcattaa
      481 ttttcgcgtt gtctcgctgc tgaaaagcga taatcacctg tctcgccgtc tcttcaaacg
      541 acggagcggc acaaacggga tgcgcggcca ttcccagcaa actcagcgcg atggccgtgc
      601 ggctcatttt catcattggc tccccattaa catccggtgt tctattagcg ccaatatact
      661 ctcgcaatat ttactcggcc tgtccgtaag cgtacaatgc ccgcccttaa agtgaggact
      721 ctcttccagc cgcctcatca ggtgaggcgg atctgacctg tcatcagaac gagaaaatga
      781 tgtttaaacc agaactcctt tcgccagcgg gaacgctgaa aaatatgcgt tacgctttcg
      841 cttacggtgc cgatgccgtc tatgcgggcc aaccgcgtta ctctttacgc gtgcgcaata
      901 acgaattcaa tcacgaaaat ttgcagcttg gcatcaacga agcccacgcg ctcggaaaaa
      961 aattctacgt ggtggtgaac atcgccccgc ataacgccaa gctcaaaacc tttatccgtg
     1021 acctgaaacc cgtcgtcgag atgggcccgg atgcgctgat catgtccgat ccagggttga
     1081 ttatgctggt acgcgagcac ttcccggcaa tgccgattca cctgtcggta caggctaacg
     1141 ccgtaaactg ggcgacggta aaattctggc agcagatggg gctgacccgc gtgattctct
     1201 cccgcgagct gtcgctggaa gagattgagg aaattcgcca gcaggtgccg gatatggaaa
     1261 tagaaatttt cgtccacggc gcgctatgca tggcctattc cggtcgctgc ctgctttccg
     1321 gctacatcaa taaacgcgat ccgaaccagg gcacctgcac caatgcctgc cgttgggaat
     1381 ataacgtgca ggaaggaaaa gaagacgttg tcggcaacat cgtgcataag catgaaccga
     1441 ttccggtaca gaacgttgag ccgacgctcg gtatcggcgc gccgacggat aaagtgttta
     1501 tgatagaaga ggcccaaaga ccgggcgaat acatgaccgc gttcgaagac gagcatggca
     1561 cctatatcat gaactcaaaa gatttgcgcg ctatcgccca cgtggagcgc ctgacgaaaa
     1621 tgggcgtcca ctcgctgaaa atcgaaggcc gcaccaaatc cttttattac tgcgcccgta
     1681 ccgcccaggt ctaccgtaag gccatcgacg acgccgccgc gggtaaaccc ttcgacccta
     1741 cgctgctgga aacgctggaa ggtctggctc atcgcggcta taccgaaggt ttcctgcgtc
     1801 gccatacgca cgacgattac cagaattacg agtacgggta ctccgtttcc gaacgccagc
     1861 aatttgtcgg cgagttcacc ggcgagcgta aaggccaact ggcggccgtg gcggtgaaga
     1921 ataaattctc cgttggcgat agtctggagc tgatgactcc gcagggaaat atcaatttca
     1981 ctctggaaca gatggagaac gccaaaggcg acgctatgcc ggtggcgcct ggcgatggct
     2041 ataccgtctg gatgcccgtc ccgcaggacg ttacgctgga ttacgcacta ttgatgcgta
     2101 atttctcagg cgaatcaacg cgtaaccccc atgctaagta gttaattgcg gttatttttt
     2161 catggcggga agattcttag aaattgatca cataccgctt cgctcaatgc gggtattatt
     2221 caacgcgctg aaaaacataa cccataaatg ctagctgtac caggaaccac ctccttggcc
     2281 tgcgtaatct cccttacgca ggcttatttt ttgcgtataa tcaataaaaa agtggtactt
     2341 cccgccacat ccgaaaattg accacactaa ccaaagcgca aatgggcgct taggtttaga
     2401 gacctcccct attcatggcc agccagcaag tcacaatcct ccctgcatct ggtcagactc
     2461 aggacttagc attctgacgt ttacgtttaa aatcagtgaa ttaaatcaat aactgctttg
     2521 tgagtactta cacaaaaagt ttccaggtta ttaaattaag gttaaaaact gataatttaa
     2581 gcgtgtaaag ttatggcacg ttttaatgcc gcttttgcaa ggattaaaat aatgttttcc
     2641 cggattagag gtttgatttc atgtcaaagt aatactcaaa ccatcgcacc tacgctcagt
     2701 ccatcttcat caggccatgt aagttttgct ggggttgatt atcctctatt accaccagat
     2761 caccaaacac ccttcccacc gtcacgtata atcggtatcc agatttattc ctttatcctg
     2821 taaaatgtga tacagattct ccattgatct aataaccacc tcaatttcac attcaagttt
     2881 ctctacagaa ctttcattga gtgagaaatt tagagccagt aataatgatt gtgagttatt
     2941 atcataacac aaatgtggtc cattattctc tgcaaaccat aaattagaat tgagaaattc
     3001 aaaagcaaga ttattattat ccggaggtct tccgcaaaaa ccgtatatca ttatatactc
     3061 actgttagtg cttgttagta agatacggta acggttatct ataataaatg agcataatct
     3121 gttttcgtca aaggcaattg aatcggcatt taatttcagt gaaaactgtc ttaataagcg
     3181 atcggctctt gaatacataa caccccatac tctatctaaa gcgtttctat ataagtcata
     3241 agcctctggt ctggacgctt aacaccccgt gtcatctccg gaattcatct tttccctatg
     3301 acttgctgtg tttgctcatt tatggccagg ctggccgggt tctgacgcca tttgcgctaa
     3361 ggtatagtcc ggcgcatatt cccatcatac caattccccc catgccaaac gatgcgccta
     3421 aaatcgtcag agcggtagta tatgcagcac cactactgac actggcgaca gcccctgagc
     3481 ataccccact gaaagcacct gtaaacaatg ccgtggttcc caggcacatt aaacatctgg
     3541 gtttattgcc gtaagcgtta aactcaacga tttcagctac cggtttttcg tcatcacccc
     3601 attcagaagg ggggagcaat ggcgtttgcg cattcacgcc tgaagtgaca ttcatataaa
     3661 cctcttcatg cacatgcctg tttatgttta tgagaaaagc gatacctcag gcaacggtac
     3721 gactataaga cactgcgcta ag
//
LOCUS       DAJVBX010000281         3742 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.281, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000281 DAJVBX010000000
VERSION     DAJVBX010000281.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3742
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.281"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..1366)
                     /gene="pykF"
                     /locus_tag="OPV72_004263"
     CDS             complement(<1..1366)
                     /gene="pykF"
                     /locus_tag="OPV72_004263"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010346010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase PykF"
                     /protein_id="HCR9916401.1"
                     /translation="MKKTKIVCTIGPKTESEEMLSKMLDAGMNVMRLNFSHGDYAEHG
                     QRIQNLRNVMSKTGKKAAILLDTKGPEIRTIKLEGGNDVSLKAGQTFTFTTDKSVVGN
                     NEIVAVTYEGFTSDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNL
                     PGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVVEIREHLKAHGGENIQII
                     SKIENQEGLNNFDEILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVIT
                     ATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATICER
                     TDRVMNSRLDYNNDSRKLRITEAVCRGAVETAEKLEAPLIVVATQGGKSARAVRKYFP
                     DATILALTTNEVTARQLVLSKGVVSQLVKEINSTDDFYRLGKDVALQSGLAQKGDVVV
                     MVSGA"
     gene            complement(1768..3111)
                     /locus_tag="OPV72_004264"
     CDS             complement(1768..3111)
                     /locus_tag="OPV72_004264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HCR9916402.1"
                     /translation="MKKVKKLSLTDLVLYGLVFMVPIAPVSLYGVVYNLSHGMVALVY
                     IIGAIAMFFTAYSYSTLSQHISSSGSAYAYAGVCINPAVGFLTGWILLLDYLLFPTLV
                     AVLGGVAVHAILPQIPVWVWPLIYVAIGTGVNYLGIQQTAKFDKLLVFIQLGILAIFV
                     LLIIRLMMQDSSQITLSFRPFFDSQWFTPGLIATAISVAALNFLGFDAISTLSEESEG
                     GGRAVSKATLLALVLATVLFIIVVAFAAFATGNVDRFAEGNATNEAFFTIAGNVGGIW
                     LKVAFSIIVAFVCAVGNIITAQTAVSRVLFSMGRDRMLPAFLAHVHTTRKTPDYAILF
                     TGGVTLLLSYLFSGKIESISTLVNFGALFAFFVVNLCVFILFNFRMKAQRRIFAHVIS
                     PIMGMIVIGYVCLNMNIHALILGISWAAIGIAILCYRKAYNQNIAIDLEGKKLLD"
     gene            complement(3133..3742)
                     /locus_tag="OPV72_004265"
                     /pseudo
     CDS             complement(3133..3742)
                     /locus_tag="OPV72_004265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460345.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
BASE COUNT          962 a          946 c          966 g          868 t
ORIGIN      
        1 gcgcgccgga gaccatcact acgacgtcgc ctttctgggc gaggccgctt tgtagggcga
       61 catctttgcc cagacggtag aaatcatcag tagaattgat ttctttcacc agctgcgata
      121 ccacgccttt gctcagtact aactgacggg cggtcacttc attggtggtc aatgccagga
      181 tggtggcgtc cgggaagtat ttacgcacgg cgcgagcgga tttaccgccc tgggtcgcta
      241 ccacgatcag cggcgcttcc aatttttcgg cggtttctac cgcgccgcgg cataccgctt
      301 ccgtaatgcg cagtttacgg ctgtcgttgt tgtagtccag acggctgttc atgacgcggt
      361 cggtacgttc gcagatggtc gccatgatag aaacggcttc cagcgggtat ttcccttttg
      421 cggattcgcc ggacagcata accgcatccg taccgtcgag gatggcgttt gcaacatcgc
      481 ctgcttctgc gcgggtcgga cgcggatttt tgatcataga atccagcatc tgagtcgcgg
      541 tgatcacgac tttacgtgcg cggatacatt tttcgatcat cattttctgc gcaaagatca
      601 cttcttcaac cgggatttct acgcccaggt cgccacgcgc aaccatgatg ccgtcggaag
      661 cttcgagaat ttcatcgaag ttgttcaggc cttcctggtt ttcgatctta gagataatct
      721 ggatgttttc gccgccgtgg gctttcagat gctcgcgaat ttcgacaacg tcagaacgtt
      781 tacggataaa ggacgcagca acaaagtcaa cgccctgttc gcaaccgaag atcaggtcct
      841 gtttgtcttt ttcagccagc gccggcagag caatagaaac gcccggcagg ttaacgcctt
      901 tgttctcgcc cagatcgccg ttgttcagca ccttacaaat gactttattg ccttcgatgg
      961 cggtcacttc cataccgatc agaccatcgt caaccaggac ggtgttgcca acgctcaggt
     1021 cgctggtgaa gccttcatag gtgacggcaa cgatttcatt attaccgacc acggatttgt
     1081 cggtggtaaa agtaaaggtt tggcccgctt tcagcgaaac gtcgttaccg ccttccagtt
     1141 taatggtgcg gatttctggt cctttagtat caagcagaat agcagctttt ttaccagttt
     1201 tgctcatcac gttgcgcaag ttctggatac gctgaccgtg ttctgcataa tcgccatgag
     1261 agaagttcag acgcatcacg ttcatgcccg cgtccagcat tttgcttaac atctcttcgg
     1321 attcggtttt cggaccgata gtacaaacaa ttttcgtctt tttcatgaca gtcttagtct
     1381 ttaagttgag gaggatatgg aaatctggct tcgggcgcgc acggcccgta agctaagcct
     1441 gtgttgctaa agtgatgatg cctcgctcta aggataggtg acatcgaaag agcgtgcaga
     1501 ggaatgtgtg ctcgcgtttc agcccaacgg gaaggggata attttagtcg ttgagtttta
     1561 cagtccaatg cgctgaaacc attcaagaga caattggcgc gcattatacg ctgaaattta
     1621 caaaaaagga aaatgaaaac cctgtttcaa aagacatctg tgcagatcca caacggtttg
     1681 ttattacgct gtttacgatg tcgctggcga tgacgccgcc cgaacagggg cggcgttgcg
     1741 caacagctgg tgttgttgcg cataatgtca atcgagcaac tttttgcctt ccaggtcgat
     1801 ggcgatgttt tggttgtatg cttttcggta gcacagtatc gctatcccga tcgccgccca
     1861 gctaattccg agtatcagag cgtgaatgtt catgtttaaa cagacgtagc cgatgacgat
     1921 catccccatg atcggcgaaa tgacatgggc gaaaatgcgc cgctgggctt tcatccggaa
     1981 attgaacagg ataaacacac acaggttcac gacaaaaaaa gcgaaaagcg cgccaaagtt
     2041 caccagcgtg gagatagatt caatcttgcc ggaaaacagg tagctgagca gcagggtgac
     2101 gccgccggta aacagaatgg cataatccgg cgttttacgc gtggtatgga cgtgagcgag
     2161 gaaggcgggc aacattcggt cgcgccccat tgaaaataac actctggaca ccgccgtttg
     2221 cgcggtaata atgttgccga cggcgcacac aaacgccaca atgatggaaa acgccacttt
     2281 gagccagata ccgccaacgt tgccggcaat ggtgaaaaat gcttcattcg tcgcattacc
     2341 ttccgcgaag cggtcgacgt taccggtggc gaacgccgca aacgccacaa cgataataaa
     2401 cagtaccgtc gccaaaacta acgccaacag tgttgcttta ctgacggcgc gtcccccgcc
     2461 ttcgctttct tcacttaatg tactgatagc gtcaaagccg agaaaattca gcgcagccac
     2521 cgaaatcgcc gttgcgatga gcccaggggt gaaccactgt gaatcgaaaa aaggccggaa
     2581 ggaaagcgtt atctgactac tgtcctgcat catcagacgg ataatgagta gcacgaaaat
     2641 cgccagaata ccgagttgaa taaagaccag taacttatcg aatttcgccg tttgctgtat
     2701 cccgagatag ttgactccgg tgccaatagc cacataaatc aacggccaga cccagaccgg
     2761 gatttgcggt aaaatagcgt ggaccgcgac accgcccagc accgctacga gcgtagggaa
     2821 caaaagataa tccagcagta atatccatcc ggtcagaaac cctacggcgg gattaatgca
     2881 tacgccagca tacgcatagg ccgaacccga cgaggagata tgctgcgata aggtagagta
     2941 gctgtacgcg gtaaaaaaca tcgcgatagc gccaataata taaaccagcg caaccatacc
     3001 gtgcgaaaga ttataaacga cgccataaag agagactggt gcgataggca ccataaacac
     3061 cagaccataa agcactaaat cggtaagaga caattttttg acttttttca tgataaatat
     3121 cttaatggct ttttatgcca gatcgcgtaa aaacgcgctt acctctgcga ggcagggcgc
     3181 gatattttct tcatgcgggt tatggctgct gccaggaata gtgaccgcgc ggcagtctga
     3241 aatgtgagag agcagcggag agacgacgcg ctcggttgcc tgatcgtttt cgccgcgtag
     3301 taccagaaca ggacagcgta tctggcacaa atggggcgta atatcccagt cggcaagttt
     3361 gccatttgcc gccagttcat tggttcccca taaaatgtga taacccgtag ggtcggcggc
     3421 gaactggcca gtatcgtccc gcgaagcccg gcaggctgta agcaggcgtg ctctgcggca
     3481 agcattccgc cccaggaatg tcccagtatc gaatacccgt gcccaatacc caggtgatga
     3541 attaattggg ttaattgacg gagataacgc gcaatagtcc agaaagacgc gtcggcatga
     3601 ggaaaatgcg ttgaacgacc gcaaccatat tgatcgtaaa atattaccat gcgcccgtca
     3661 tcagccagac ggcgataatt taataaataa tcaaagccgc cagaagggcc gccatgaagg
     3721 ataatgagcg gcgtgagtaa tg
//
LOCUS       DAJVBX010000282         3690 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.282, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000282 DAJVBX010000000
VERSION     DAJVBX010000282.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3690)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3690)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3690
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.282"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(137..1288)
                     /locus_tag="OPV72_004266"
     CDS             complement(137..1288)
                     /locus_tag="OPV72_004266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001685958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR9916403.1"
                     /translation="MYLREVFYYPWNEYFSLTNTQSGMLMSWLGFVGIISGAVSGIIV
                     DRFKNPKSILTIAYLTMAALAIWQSFRPSYQAMFIIVGFMSLVGNGLFLVSMTKIARL
                     LASDNEQGRYFGFLESGRGIAGTVLTLCAVAIVGLHGSSAVSIGFILRFDAAIYIILG
                     FTSYYLFPKGVSAIENAAPKKMSDLISLLKSVKLWLAAFIISCVIFVYQGGAYLVPYL
                     SDAYGMTPDQTAVIGMIRAYFLAFIISPFAGLLADKIGSSLKVMASFFILGALITASF
                     IFIPHDSRFLILLITLVLLLGALTFGMRGIMYAQVNEIRIPKVFTGTAMGILICIGFS
                     PEAYVHLIFGYLLDTYKEFAYTLMFATIAVVLFAGALCSGLLYRINKKV"
     gene            complement(1432..2079)
                     /locus_tag="OPV72_004267"
     CDS             complement(1432..2079)
                     /locus_tag="OPV72_004267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HCR9916404.1"
                     /translation="MKNTCLEPYEFLIDFLADYFGENTEVVLHNLSDLESSIHKIRNG
                     HISGRSVGDPITDLVVRAMKNNDSEVHYQCNYLSKTRDGRRLKCATFFIRNKQGEIVG
                     ALCLNTVVEDLIALNDKLSHFLSIFVGQTDNNNGTQLDEHIGLTIPEMVDLKINNVIN
                     IENINPESLNAENKSHIISLLNDEGVFLLKGAVTKVAKKLNISEPTVYKYIQKLK"
     gene            complement(2118..2498)
                     /locus_tag="OPV72_004268"
     CDS             complement(2118..2498)
                     /locus_tag="OPV72_004268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HCR9916405.1"
                     /translation="MKEIIFTETAPAAIGSYSQGNAMGNLIFTSGQLPINADSGKIET
                     DDIQEQTRQSLLNLLAVVKMAGGDTDTVLKTTCFLSDMADFAAFNDVYASFFKINPPA
                     RSCFAVKTLPMGARVEIEAVAFRQ"
     gene            complement(2508..3674)
                     /locus_tag="OPV72_004269"
     CDS             complement(2508..3674)
                     /locus_tag="OPV72_004269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HCR9916406.1"
                     /translation="MKYDFNEIYQRIASEKWEYDSVINGFPVIPMSVADTDLVSPVEV
                     RQALIEVCNRREFGYPAYHDDFKDVLASWYDRYYDWRPDTADIIETPPLLMTMGAFIR
                     GMTQCNESVVVMTPVYHSFARTIRENHRAVTECDLLRDENNHYTIDFEKLEDTCSRPE
                     NKILIFCNPHNPVGRCWTEEEVRKVAAIAQKTGTILISDEIHADFVYDEKCYTPVMKA
                     AENLNGIIVFLSGGKLFNIGGIFSSYVFTADPVFKKQMAVVLKELHFQPTAFAHEAAY
                     AGYKYYHDYREEVVNHIRKMQIKLVNGLNNMPYPVKANLPEATYLVWADFNDTGWSGD
                     RIQEFLVQDAGLGFNRGDQFGVAGTGFARINCGVPESRIDEALSRLEKAFSKYF"
BASE COUNT         1121 a          824 c          727 g         1018 t
ORIGIN      
        1 cattaatctc agctgggttt tgaagcagac cgcattcagg tcggatactg gccaacaaca
       61 ccagatacag aataaggccc ctgacagggc cttctggtag tatgtagtcg atatttacac
      121 tgtttacaac ggggagtcat actttcttat taatcctgta aagcaaacca ctgcacagtg
      181 cgccagcaaa aagaacaact gcaatagtgg caaacatcag cgtatatgca aattctttat
      241 acgtatcaag aaggtatccg aagataagat ggacataagc ttccgggctg aatccgatgc
      301 agattaatat ccccattgcg gtcccggtaa acactttcgg tatgcgaatt tcatttacct
      361 gcgcatacat tataccgcgc atgccaaacg taagcgctcc cagtaataaa accagagtaa
      421 taagcaggat cagaaatcgt gagtcatgag gaataaatat aaaagatgca gttatcaatg
      481 caccgagaat aaagaagctg gccataactt tcagggaaga accaatctta tctgcaagta
      541 ggccagcaaa aggcgaaata ataaaagcga gaaaatatgc cctaatcatc ccgataacgg
      601 cagtttggtc gggagtcatt ccataggcat cggagaggta tggtaccaga taagctccgc
      661 cctggtaaac aaaaataaca cagctgataa tgaatgctgc cagccaaagt tttacacttt
      721 tgagtagtga aataagatcc gacatttttt taggtgccgc attttcaata gcactaacac
      781 ctttcggaaa taaataataa gaggtgaatc ccagaataat ataaatggct gcgtcaaatc
      841 gtaaaataaa accaatgctg acagcactgg agccatgcag accaacaata gccacggcac
      901 ataacgtcag aacagtgccg gcaattccac gaccggactc cagaaatcca aaataccgcc
      961 cctgctcatt gtctgatgca aggagtctgg caatttttgt catggaaacc aggaacagtc
     1021 cattaccgac taaggacata aatccgacga taataaacat ggcctgatag gaaggccgga
     1081 aggactgcca gatggcaagg gccgccattg tgagataggc aatggtaaga atgcttttag
     1141 gatttttgaa acggtcaacg atgatgcctg aaacagcacc tgatataatg cctacaaacc
     1201 cgagccagct cattaacatg cccgattgtg tatttgtcag tgaaaagtat tcattccacg
     1261 gatagtagaa tacttcacgc aaatacatag ccttgaatat tgttccccca ccgactgcca
     1321 gaagaataaa aaaatcaggt tatgcctttt aatcgatttg tcttctgcat gttccatatg
     1381 tccgcctgta taactagacg ttattgtaga ttgatccgtt agtgtcttgt gttattttaa
     1441 tttttgtatg tatttataaa cagtgggttc agatatgtta agttttttgg ctactttcgt
     1501 tactgcccct ttaagcagaa atacgccttc atcatttagt aatgaaataa tatggctttt
     1561 attttcagca ttcagtgact ctggattaat attttcaata ttgattacat tattaatttt
     1621 gagatcaacc atttcaggaa tggtcagtcc aatatgttca tcaagctgag tgccgttatt
     1681 attgtcagtc tgcccgacaa aaatgcttaa aaaatgacta agtttatcat tcagggcaat
     1741 taaatcttcg acgacggtat tcagacatag tgcaccaaca atttctccct gcttattccg
     1801 gataaaaaaa gtggcacact taagccgtct gccatcgcgt gtcttgctga gataattaca
     1861 ctggtaatgt acctcactgt cattgttctt catggcacgg actaccagat cggtgatggg
     1921 atctccgaca gagcgaccgc tgatatgtcc atttctgatt ttatgtatag aagactcaag
     1981 atcagaaaga ttgtgcagaa caacttccgt gttttcgcca aaataatcgg ccaggaaatc
     2041 gatcaaaaat tcatagggtt caagacaagt gtttttcatg gttaatctgg ttgccacctc
     2101 agtggcaacc acctttgtta ttgacgaaat gccacagctt caatctcaac tctggcaccc
     2161 ataggaagtg tttttacagc aaaacagctg cgtgccggcg gatttatctt aaaaaagctg
     2221 gcatagacat cgttgaacgc agcaaaatca gccatatcac tcaagaaaca ggtcgttttc
     2281 agtaccgtat cagtatcacc gcctgccatc ttaactacag ccagaagatt aagcagtgac
     2341 tgacgggtct gttcctgaat atcatcagtt tcaattttgc cactgtcagc gttaatgggc
     2401 aattgtccgg aggtaaaaat taaattaccc atcgcattgc cctgactgta tgagccaatt
     2461 gctgccggtg ctgtttctgt aaaaataatc tctttcactt ctgttcctta aaaatactta
     2521 ctgaatgcct tttccagacg actcagtgct tcatcaatac gtgactccgg aacaccacag
     2581 ttaattcggg caaatccggt accggcaaca ccaaactgat ctccccggtt aaatccgagt
     2641 cccgcatcct gcactaaaaa ttcctgaatg cgatcacctg accagcccgt atcattaaag
     2701 tcggcccata caagataagt ggcttccggc agattggctt ttaccggata tggcatgtta
     2761 ttgagcccgt taaccagttt aatctgcatt ttacggatat gattcaccac ctcttcacga
     2821 tagtcatggt aatatttata tccggcatag gcggcttcat gcgcgaacgc agtgggctga
     2881 aaatgtaatt ctttcaggac aactgccatc tgttttttaa atacaggatc ggccgtgaag
     2941 acataggaac taaaaatacc gccaatgtta aacagcttcc ctccggataa aaaaacgata
     3001 atgccattta aattttccgc agctttcatg accggcgtat agcatttttc gtcatagaca
     3061 aaatctgcat gaatttcgtc agaaatcagg attgttcctg ttttctgggc aattgcggcg
     3121 actttcctga cttcctcttc agtccagcaa cgacctaccg gattatgagg gttacagaaa
     3181 atcagaatct tattctccgg gcgtgaacag gtatcttcca gcttttcaaa atcaatagtg
     3241 taatgattgt tttcatcacg cagcagatca cactcagtta cagcacggtg gttttcacgg
     3301 atggttctgg caaaagaatg atagaccggt gtcataacca caacggattc attacactgt
     3361 gtcattcccc tgataaaagc gcccatcgtc atcagtaaag gcggtgtttc aataatatca
     3421 gccgtatccg gccgccagtc ataatatcga tcataccagg atgccagcac atccttaaaa
     3481 tcatcatgat aggccggata tccgaattct ctgcggttac agacttcaat cagtgcctga
     3541 cgaacctcca cgggagaaac taaatcggta tctgcaacag acataggtat tactggaaat
     3601 ccattaatga cactgtcata ttcccatttt tctgatgcta ttctctgata gatttcatta
     3661 aaatcgtatt tcattttatt ttccttaatt
//
LOCUS       DAJVBX010000283         3619 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.283, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000283 DAJVBX010000000
VERSION     DAJVBX010000283.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3619)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3619)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3619
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.283"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..302
                     /locus_tag="OPV72_004270"
     CDS             <1..302
                     /locus_tag="OPV72_004270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF4440 domain-containing protein"
                     /protein_id="HCR9916407.1"
                     /translation="ALIARFAVDFTMITPGGICLDYPALGAFFQAQRACRPGLVIMVE
                     HIDLVAEWPEGAALRYRERQQLPGQAETVRWSTVILKRERGRIVWRHLHETTATA"
     gene            complement(358..2925)
                     /gene="mutS"
                     /locus_tag="OPV72_004271"
     CDS             complement(358..2925)
                     /gene="mutS"
                     /locus_tag="OPV72_004271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HCR9916408.1"
                     /translation="MNESFDKDFSNHTPMMQQYLKLKAQHPEILLFYRMGDFYELFYD
                     DAKRASQLLDISLTKRGASAGEPIPMAGIPHHAVENYLAKLVNQGESVAICEQIGDPA
                     TSKGPVERKVVRIVTPGTISDEALLQERQDNLLAAIWQDGKGYGYATLDISSGRFRLS
                     EPADRETMAAELQRTNPAELLYAEDFAEMALIEGRRGLRRRPLWEFEIDTARQQLNLQ
                     FGTRDLVGFGVENASRGLCAAGCLLQYVKDTQRTSLPHIRSITMERQQDSIIMDAATR
                     RNLEITQNLAGGVENTLAAVLDCTVTPMGSRMLKRWLHMPVRNTDILRERQQTIGALQ
                     DTVSELQPVLRQVGDLERILARLALRTARPRDLARMRHAFQQLPELHAQLETVDSAPV
                     QALRKKMGDFAELRDLLERAIIDAPPVLVRDGGVIAPGYHEELDEWRALADGATDYLD
                     RLEIRERERTGLDTLKVGYNAVHGYYIQISRGQSHLAPINYVRRQTLKNAERYIIPEL
                     KEYEDKVLTSKGKALALEKQLYDELFDLLLPHLADLQQSANALAELDVLVNLAERAWT
                     LNYTCPTFTDKPGIRITEGRHPVVEQVLNEPFIANPLNLSPQRRMLIITGPNMGGKST
                     YMRQTALIALLAYIGSYVPAQNVEIGPIDRIFTRVGAADDLASGRSTFMVEMTETANI
                     LHNATENSLVLMDEIGRGTSTYDGLSLAWACAENLANKIKALTLFATHYFELTQLPEK
                     MEGVANVHLDALEHGDTIAFMHSVQDGAASKSYGLAVAALAGVPKEVIKRARQKLREL
                     ESISPNAAATQVDGTQMSLLAAPEETSPAVEALENLDPDSLTPRQALEWIYRLKSLV"
     gene            3083..3603
                     /locus_tag="OPV72_004272"
                     /pseudo
     CDS             3083..3603
                     /locus_tag="OPV72_004272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461829.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
BASE COUNT          805 a          973 c          986 g          855 t
ORIGIN      
        1 aggcgttgat agcgcgtttt gctgttgatt ttacgatgat aacgccagga ggtatttgtc
       61 tggattatcc ggcgctgggc gcttttttcc aggcgcagcg cgcgtgtcgc ccggggctgg
      121 ttatcatggt tgagcacatt gatcttgtgg cggagtggcc ggaaggcgcc gcgctgcgtt
      181 atcgtgagcg ccagcaactg ccgggccagg ccgagacggt acgctggtcg acggtcattt
      241 taaaaaggga aagaggacgg atagtctggc gtcatttaca tgaaacgaca gccacagcct
      301 gaaaagcctg ttccggcgcg cagacccgat agcgcggcgc tatcgggtct gacacgttta
      361 caccagactt ttcagccgat agatccactc cagcgcctgg cgtggcgtca gggagtccgg
      421 atcgagattc tccagcgctt caacggcggg cgatgtctcc tccggggcgg caagcaacga
      481 catttgcgtg ccgtccacct gcgttgccgc cgcattgggc gagatgcttt ccagctcgcg
      541 gagtttttgg cgcgcgcgtt tgatgacttc tttagggacg cccgcaagcg ccgcgaccgc
      601 caggccatag ctcttacttg ccgcgccgtc ctgcacgctg tgcataaacg cgatagtatc
      661 gccgtgttcc agcgcatcca ggtggacgtt cgccacgcct tccattttct ccggtaattg
      721 ggtcagctcg aagtagtggg tagcgaacag cgttaacgct ttaatcttat tcgcgagatt
      781 ctccgcgcag gcccaggcca atgacagccc gtcatacgtg gaggtaccgc gcccgatttc
      841 atccatcaat accagactgt tttccgtcgc attatgcaga atgttcgcgg tttcggtcat
      901 ctccaccata aaggtcgaac gcccggaagc caggtcgtcc gctgcgccga cgcgggtaaa
      961 aatacggtcg atggggccga tttccacgtt ttgcgccgga acgtaactgc cgatataggc
     1021 cagcagggcg atcaatgccg tttgtcgcat ataggtactt ttaccgccca tattggggcc
     1081 ggtaatgatc aacatccggc gctgcggcga cagattgagc gggttagcga taaacggctc
     1141 attcagtacc tgttcaacca ccgggtggcg accttcggta atacggatac cgggtttatc
     1201 ggtaaatgtt gggcaggtgt aattcagcgt ccaggcgcgt tcggccaggt taaccagcac
     1261 atccagctcc gccagagcgt tggcgctctg ctgtaaatcg gccagatgcg gcaacagcag
     1321 atcaaacaat tcgtcatata gctgtttttc cagcgccagt gctttgcctt tcgaggtcag
     1381 aactttatct tcgtactctt taagctcagg aataatgtag cgttcggcat ttttcagcgt
     1441 ctggcgacgc acataattga tgggcgccag atggctttga ccacggctaa tctgaatgta
     1501 ataaccatgt accgcgttat agccgacttt cagcgtatcc agcccggtac gctcgcgttc
     1561 gcgaatttcc agacgatcga gataatcggt ggcgccgtcc gccagcgcgc gccattcatc
     1621 cagctcttca tggtagccgg gcgcaataac gccgccgtcg cggaccagta ccggcggcgc
     1681 gtcaataatg gcgcgctcca ggaggtcgcg cagttcggcg aaatcgccca tttttttacg
     1741 caacgcctgt accggcgcgc tgtcaacggt ttcaagctga gcgtgcaatt ccggcagctg
     1801 ctggaaggcg tgacgcattc gggcgagatc gcgcggacgc gcggtgcgca gcgccagacg
     1861 cgcaaggatg cgctccagat cgccgacctg acgcagcacc ggttgcagtt cgctgacggt
     1921 atcctgcaag gcgccgatgg tctgctggcg ttcacgtaat atgtcggtat ttcgtaccgg
     1981 catatgcagc cagcgtttaa gcattcggct acccattggc gtcacggtac agtcaagcac
     2041 cgcggcgagg gtattttcga caccgccggc caggttctgg gtaatttcca gattgcggcg
     2101 ggtcgcggca tccataatga tgctgtcctg ctggcgttcc atcgtaatgg aacgaatatg
     2161 cggcagggag gtgcgctggg tatcttttac gtactgtaac aggcagcctg ccgcacataa
     2221 tccacgcgag gcattttcga cgccgaaacc gaccagatcc cgcgtaccga attgcagatt
     2281 taactgctgg cgggcggtat caatctcaaa ctcccacaac gggcgacggc gcagaccccg
     2341 gcgtccctct attaacgcca tttcagcaaa atcttcggca tacaacagtt cggcgggatt
     2401 ggtgcgctgc agctctgcgg ccatcgtttc acggtcggcg ggttcgctca gacgaaagcg
     2461 cccggagctg atatccagcg tggcgtaacc gtagccttta ccatcctgcc agatagccgc
     2521 cagcaggtta tcctgacgct cctgtaacag ggcttcatcg ctgatggtgc caggcgtaac
     2581 gatacgcacg actttacgtt caacgggacc tttgctggtg gccggatcgc caatctgttc
     2641 gcaaatagcg acggattcgc cctgattgac cagtttcgcg aggtagtttt ctacggcgtg
     2701 gtgcgggata cccgccatag ggataggttc gccagccgat gcgccgcgtt tggtcagcga
     2761 aatatcgagc aactgcgacg cacgctttgc gtcgtcataa aacagctcgt aaaagtctcc
     2821 catacgataa aagagcagga tctccggatg ctgggctttc agcttgagat actgctgcat
     2881 catgggggtg tggttggaga agtccttatc aaatgactca ttcatattga ttttactcgt
     2941 tttttattct ttcaagtgct catgtggcca taggtaaaac ccctataaac tcacataaac
     3001 ccataaattt gtagctcatc tgtagcctaa aatgtgacag gttacattct catcattcct
     3061 ggactacaac aggggtgata ctttgaaaac aactctcagc cagcctttca ttatcaacaa
     3121 gttaagtatc aatgttaagt ctgcgctcag tcgctctgga aaaatcgttt tcgaagctaa
     3181 cccagctcaa aaactctaca ttgttttcga tgaccacaga caagctcctg ctggtttcgg
     3241 ggtaaaagcc agtttgacga aaaaaaccta cgtaatccag cgaagagtag cctcgtcaga
     3301 tcgtaatgtc agtgagggta ggaagccaag ttctgtcttg aaagtaaaag ttgaaaatgt
     3361 gttcgatttt ccaaatattg acgaaacaag gcaatctgca ggcaattagt tcagaccatg
     3421 ttcgcaacaa agagaaatca caacaaaatt aagagggaaa cggatgcttc cgaactcaag
     3481 accgtaatca agattgtgtt gcatgaaggc aagccgatcc atttcgccac cacggttatt
     3541 gtgctttatt ccgataggta tcttgagctg tgcgatcttt actcttctca ggcgatcgag
     3601 taactacctg cgtcggatt
//
LOCUS       DAJVBX010000284         3580 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.284, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000284 DAJVBX010000000
VERSION     DAJVBX010000284.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3580)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3580)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3580
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.284"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(451..1059)
                     /locus_tag="OPV72_004273"
     CDS             complement(451..1059)
                     /locus_tag="OPV72_004273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1062 domain-containing protein"
                     /protein_id="HCR9916409.1"
                     /translation="MKVIWTVTPVGYQRIAKRCPSCSVKRDFTPSGAFRVNSQKKVLD
                     VWSIYKCTHCDYTWNISLFSRLPVSKINRNLYCRLMANDAATVQYFAYDNAILKRNNA
                     ELSGQPDFHIQERWLVSIASHKQVSVSVRISRSFQVSLLSILKKQLLLSAAEIKRRIE
                     TGQISGVTMKMLKSRKLKNAKYDLQLSVETLYDRRRIVLTRR"
     gene            1547..1804
                     /locus_tag="OPV72_004274"
     CDS             1547..1804
                     /locus_tag="OPV72_004274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjhX family toxin"
                     /protein_id="HCR9916410.1"
                     /translation="MNLSRQEQRTLHVLAKGGRITHIRDASGRVTAVECYSREGLLLA
                     DCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRAQPDNR"
     gene            1809..3440
                     /locus_tag="OPV72_004275"
     CDS             1809..3440
                     /locus_tag="OPV72_004275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HCR9916411.1"
                     /translation="MMMDISAVIFATHRIRLLPDEGKIPWDEPAFSQRMLENHLSQDH
                     DWASRRLTVIEQQVTWITRQLPAGARILDLGCGPGFYTRLLAERGFHCTGVDFSPASI
                     TWARQQAQAANLNIDYIQQDIRTYHPTEPFDFIMMTFGELNVFSAADAQSLISHCAQW
                     LKPDGKLLVEVHTFDEVKRQGMAQPGWQRCPHGLFLAVPHLLLTENAWDEEAQTSSTQ
                     FWAIAENGCTTRFGSQMKAWRDDEYISLLGDAGFTVLQRPDSHTWPVGETFAGKLFAL
                     LAEKASTSEGIALSKRNNPMDIPRIFTISESEHRIHNPFTAEKYATLGHALRMKPGMR
                     ILDLGSGSGEMLCTWARDYGVTGTGIDISPLFTTQAKQRAEELGVSEYVHFIHNDAAG
                     YIDEEKYDVAACVGATWIAGGVAGTIDLLAKSLKPGGIILIGKPYWRQIPATEEIAHA
                     CGVSSVADFRPLPELVAFFDQLGYDVVEMVLADPQGWDRYEAAKWMTMRRWLEENPDD
                     EFAQEVRTELTAAPKRHVTWTREYFGWGVFALIAR"
BASE COUNT          916 a          914 c          848 g          902 t
ORIGIN      
        1 caataagatt atttgctcgc gtatttctaa cggaatatct tcatataaca gatcgctatg
       61 ccttagtaag tatggtctaa aggtgtgcat tcctccccct gtaaccgcaa cagaaaaaat
      121 tacgctatga atagcgccac attactctaa ttcagtggtt caggtattaa tatcagctca
      181 acagtgagcc atttcttctt attttttaat ggtgttgcgt gaatatttat ttactctaca
      241 gataaagata attgtaaccc atcgcccttt gtcattctgc tgatcatcac tggtgcgaaa
      301 acgtctggat tatccgtggc gattcagtct tcactgaatg ccacagacaa gcgttattca
      361 actaaagctc acctgtccct tagtccttct ttcattccgt tgcgtcgttg ccataccagc
      421 acacttaaac gtaaggtgag cttattgttt ttatcgacgg gtcagaacaa tccttcgccg
      481 gtcatacagt gtttcaacag agagctgcaa atcatatttc gcattcttca gttttcgcga
      541 tttaagcatt ttcatcgtga cgccacttat ttgccctgtt tcaatccgtc tcttgatttc
      601 ggctgcgctt agcaggagtt gcttcttcaa aatcgacagc aggctgacct gaaaagaacg
      661 ggaaatcctg acgctaacac tgacctgctt gtgggaggcg atactgacca gccaccgttc
      721 ctgaatgtga aaatcaggct gccccgataa ttcagcattg tttcgcttca ggatcgcgtt
      781 gtcataagca aaatattgca ccgtggcagc atcattcgcc atcagccggc aataaagatt
      841 gcggttaatt ttgctgactg gcaggcgcga gaacagggag atattccagg tgtaatcgca
      901 gtgtgtgcat ttatagatac tccagacatc gagtaccttc ttttgcgaat taacccgaaa
      961 tgccccagaa ggcgtgaagt cccgttttac gctgcatgaa gggcaacgtt tcgctatgcg
     1021 ctgatacccc acaggagtga cagtccatat gactttcata acgtaccttt tttaacccat
     1081 acaaaaccgg atccgaactc agcggaccat aaatgtttgt gtatgaaaaa tatttaagtg
     1141 atatttttca gcgggttaaa aaaagatttc caacgctaca accctgtcaa cggccaaaag
     1201 atacgtcgag actatcaaag cggccattat cgggtatatg agtttaatca atattcatta
     1261 tggtaattgc gggagctatt catctgatac gctaaacgtc atgagcctcc ctttgagatc
     1321 acacttttca ctcccggtta ttcacttaca gaaatcaggt gttatcattc actacgtaaa
     1381 tacctttcaa ctcaacccga ggctttgatg ctggagaatg tcatcatctg ataatcagtt
     1441 acccgacctt ttcaggccgg actgattatc aatgcgccga aatcgaatgc ggacaccgca
     1501 gtgtgtttgc acgttttgcc tatgatgatt aaacaggttc ttcagtatga atttatcccg
     1561 tcaggaacaa cgtaccttac acgttctcgc caaaggcgga cgcattacgc acatccgcga
     1621 tgcgtcaggc cgcgtcaccg ccgttgagtg ctatagccgc gaagggttgt tgctcgccga
     1681 ttgcacgctc gctgtattca aaaaactcaa aaccaaaaag ctgatcaaat ccgttaacgg
     1741 tcagccctac cgcattaata caaccgggct gaacaacgtt cgcgcccagc ctgacaatcg
     1801 ctaaggagat gatgatggat atcagcgccg ttatttttgc aacgcatcgc attcggctat
     1861 tacccgatga aggcaaaatc ccctgggacg agccagcctt cagccaacgc atgctggaaa
     1921 atcatctgtc acaggatcac gactgggcca gccgccggct aaccgtgatt gagcaacagg
     1981 taacatggat tacccgtcag ttacccgcag gcgcccgcat tctggatctc ggctgtggcc
     2041 ccggttttta tacccgcctg ttagcagagc gtgggtttca ctgcacaggc gtagatttct
     2101 ctccggcatc catcacatgg gctcgccagc aggcgcaagc cgcaaacctg aatattgact
     2161 acattcagca ggatattcgt acataccacc ccacggaacc ctttgatttc attatgatga
     2221 cgtttgggga actgaatgtc tttagcgctg ctgatgcgca aagcctcatc agtcattgcg
     2281 cgcagtggtt gaaaccggac ggcaaactgc ttgttgaagt gcataccttc gatgaagtta
     2341 aacgccaggg catggcgcag ccaggctggc agcgttgtcc gcacggcctg tttcttgccg
     2401 tgcctcatct gctgttaacg gaaaatgcct gggatgaaga ggcccaaacc agctcaacgc
     2461 agttctgggc gatagcggaa aacggctgta ccacccgttt cggcagtcaa atgaaggcct
     2521 ggcgcgatga tgaatatatc agcctgcttg gtgatgctgg cttcactgtg ttgcagcgcc
     2581 cggacagtca cacctggccg gtcggcgaga cttttgcagg caagctgttt gcgctgctgg
     2641 ctgaaaaagc atccacttct gagggtattg ccctcagtaa aaggaataac ccaatggata
     2701 tcccacgtat ttttaccatt agcgaaagcg aacaccgtat ccataatccg tttacagcgg
     2761 aaaagtacgc cacgctgggc catgcgttac gcatgaaacc aggcatgcgg attctcgatc
     2821 tcggtagcgg ttcgggtgag atgctctgca cctgggctcg cgattacggt gttacaggta
     2881 ctggcattga cataagcccg ctcttcacca cacaggcaaa acaacgtgca gaagagctcg
     2941 gcgtcagtga atacgtacat tttattcata acgacgcggc cggttatatc gacgaggaaa
     3001 aatatgacgt ggcggcctgc gtaggcgcta cctggattgc gggcggtgtc gcggggacaa
     3061 tagatctgct ggccaaaagc ctcaaacctg gcgggatcat tctcatcggt aaaccgtact
     3121 ggcgtcagat ccccgcaacg gaagagatcg cccacgcctg tggcgtctca tccgtcgccg
     3181 attttcgccc cctgcccgag ctggtcgcct ttttcgacca actcggctat gacgtagtgg
     3241 aaatggtgct ggcggacccg caaggctggg acagatatga agccgctaag tggatgacca
     3301 tgcgccgctg gctggaggaa aaccctgacg atgagtttgc gcaagaggtt cgaacagaac
     3361 tgacggcagc ccccaaacgt cacgtcacct ggacgcgaga atactttggc tggggcgtat
     3421 ttgcgttaat cgcgcgataa cgtgaagcag gaggtatacc ctacaagagg tatacctcca
     3481 tttaaaagta ttcaacaaat taacacggct caaggcggga atatatcgtc ttaatttcgc
     3541 cattaagttt ctgccacaat atgtcgcaag acgtgcaagc
//
LOCUS       DAJVBX010000285         3533 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.285, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000285 DAJVBX010000000
VERSION     DAJVBX010000285.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3533
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.285"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..546
                     /locus_tag="OPV72_004276"
     CDS             <1..546
                     /locus_tag="OPV72_004276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCR9916412.1"
                     /translation="QEEIEKLLSATDRMPFPERNRCLILMAFIHGFRASELLGLRLSD
                     IDLAGRQLYIRRLKNGFSTCHPLLPDEYNVLKSWLRARKYLEKGADGDWLFLSLRRHP
                     LSRQQFFYILREAGRLAELTIAPHPHMLRHACGYALADKGIDTRLIQDYLGHRNIQHT
                     VRYTASNAGRFHGIWRKKRRV"
     gene            724..1059
                     /locus_tag="OPV72_004277"
     CDS             724..1059
                     /locus_tag="OPV72_004277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916413.1"
                     /translation="MQPKSRTGQGVREQCLDGARRHFSYRHGMAPGPRKGADMLFPQH
                     EAAVAGAVPGRQWPEENNLMTQEYAEMSTGRGGTSKCRYSMGAKIFLLLLAVSTVAAL
                     FSLYQVLTY"
     gene            1061..1801
                     /locus_tag="OPV72_004278"
     CDS             1061..1801
                     /locus_tag="OPV72_004278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transport protein"
                     /protein_id="HCR9916414.1"
                     /translation="MQTLTRVLPPLRLIMFCQSGENPTQFPDTGGLCVEDCVRLRTPE
                     GLLDRLRRWPGAMVISAGRPSTQLLLWQQVFLRYPRTVVFCSSNAFLPVDVSVEGYFR
                     HLRLIKRAMSVRVLARMAELAIWSSLQTSPYEEEMKSALSVPELVMEINSRTLVRLLS
                     ERLPKQGRRVLGLLLSGCSPEMTARMLGTGVRQVWLAEQTLKQRWDIPTGVPLSDAVR
                     IRIPDVGPDISQQSGLVKTGAGNAPDLC"
     gene            2087..3237
                     /gene="glf"
                     /locus_tag="OPV72_004279"
                     /pseudo
     CDS             2087..3237
                     /gene="glf"
                     /locus_tag="OPV72_004279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459704.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            3234..>3533
                     /locus_tag="OPV72_004280"
     CDS             3234..>3533
                     /locus_tag="OPV72_004280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCR9916415.1"
                     /translation="MMKCTALIVTFNRLEKLKKSVRETVKAGFSSIVIVNNGSSDGTR
                     EWLSSLSEPGITILNLKDNLGGAGGFKVGSQYICSYSNADWVFFYDDDAYPEINIL"
BASE COUNT          963 a          739 c          880 g          951 t
ORIGIN      
        1 caagaagaga ttgaaaaact gctgtcagcg accgacagaa tgcccttccc ggaaagaaac
       61 cgctgcttaa tcctgatggc gtttattcac ggcttccggg ccagtgagct gctggggctg
      121 cgcttgtcgg atattgatct tgcaggaaga cagctttata tccggcgcct caaaaatggc
      181 ttttcaacgt gtcaccccct ccttcccgat gagtataacg tactgaaaag ctggctcagg
      241 gccaggaagt atcttgagaa aggggctgac ggagactggc tgttcctgtc gctacgacgg
      301 catccgctca gcaggcaaca atttttttac atacttcgtg aggcagggcg gttggccgaa
      361 ttaacgatag cgccacatcc tcatatgctg cgacatgcct gcggctacgc ccttgctgat
      421 aaagggattg atacacgact catacaggac tatctggggc acaggaatat ccagcacacc
      481 gtaagataca ccgcaagtaa cgccgggcgt tttcatggaa tatggcgaaa aaaacgtcga
      541 gtataaccgt acgttctgat tcatattgtt aaatcacaga gaagtctgtt cagggaaagc
      601 tgatttacat aatcaacata taaatcaata gattactgta ttttctattt gtcattttgt
      661 actccgcaca gggcagaatt accctacggc aggagcatgt actaccaggg ggactgacgg
      721 cctgtgcagc cgaaaagcag aaccggacag ggtgtcagag agcagtgttt agatggggcc
      781 agacgtcatt tttcatacag acatggaatg gctcccggtc cacgaaaggg tgcggacatg
      841 ttgtttccac aacacgaagc tgccgttgct ggcgcagtgc cgggtcggca atggccagag
      901 gagaacaatc tgatgacgca agaatatgcg gaaatgtcca ccggaagggg ggggaccagt
      961 aagtgccggt acagtatggg cgcaaaaata tttttgctcc tgctggcggt ctccactgtc
     1021 gcagcgttgt tcagcctgta ccaggttctg acgtactgat atgcagacgt taaccagagt
     1081 actgccgcct ctccggctga ttatgttttg tcagtcaggc gaaaatccta cgcagtttcc
     1141 ggataccggc ggcctttgcg tggaggactg cgttcgtctc aggacaccag aagggctgct
     1201 ggatcggttg cgtcggtggc ccggcgcgat ggtgatatcc gccggacggc catcaaccca
     1261 gcttctgctg tggcaacagg tttttctgcg ttatccgcgg acagtggttt tttgcagcag
     1321 taacgcgttt ttaccggttg acgtcagcgt ggaaggttac ttccgccatc tgaggctgat
     1381 taaacgcgcc atgtcggtaa gggttctggc cagaatggct gagcttgcca tatggtcatc
     1441 actacagaca tcgccttacg aggaggagat gaaaagcgcg ttgagcgtgc cggagctggt
     1501 gatggagata aacagccgca cgctggtcag gttactgtca gagcgtctgc caaaacaggg
     1561 acggcgggtg ctgggattac tgttgtcagg ctgtagcccg gaaatgacgg cccgtatgct
     1621 gggaaccggc gtgaggcagg tctggctcgc ggagcagacg ctgaaacaac gctgggatat
     1681 cccgacagga gtaccgctat ctgatgcggt aagaataagg ataccggacg tcggtccgga
     1741 catcagtcaa cagagtgggt tggtaaaaac tggggccggt aacgcaccgg atttatgctg
     1801 acagcatatt tacatcatgc cgcgcggtat tcagacccat aatgttgcgt tctgaatgag
     1861 ttatcttcac aaaataaata tggcaatcat cgttgtccgg aaataccgca taacgtgtaa
     1921 cattaatgaa tctgtaatca gtgcgagggt ttacgcgctg tggcggtagc gtggaattat
     1981 ctggatgcgt tgagtaaatt tcactttact cttctgatat aaatgaaaat ggttctggat
     2041 aaactatcta atattatctg tgtctgcgaa cagagtgaca aaaataatgc aacgtaaaaa
     2101 gatactaatt gtaggtgcgg gcctttcagg cgcagtaata gcacgccagt tagccgagca
     2161 gggacatgta gtcaatatta ttgatcaacg ttcgcatatc ggtagtaacg cttatgatgc
     2221 ccgagatgag cacacgggta ttatggtgta cgtttatggt cctcatattt ttcatactga
     2281 taatgaaact gtatggaatt atgtaaataa atacgctgag atgatgcctt atatcaataa
     2341 ggttaaggcc acagtaaatg gtcaggtatt ttctctacct atcaatcttc ataccatcaa
     2401 tcaatttttt ggtgtcgcct gctcacctga tgacgccagg aaattactgc ttcaaaaatg
     2461 tgatagcacc attctggaac cacaaaattt tgagcaacag gccttgcgtt tcattggtaa
     2521 agagttatat gaagcctttt ttaaaggtta taccattaaa caatgggggc ttcatccttc
     2581 cgcgttaccc gcttctgtat tgaaacgtat ccctgttcgt tttaattatg atgataacta
     2641 tttcaatcat aagtttcagg gaataccaaa atttggttat acacaaatgg tcaagtccat
     2701 tgtcgaacac gaaaatatcg ctgttgaact atgtcgctcc ttcactcaag aaatgcggac
     2761 aaattatgat catgtttttt tcagtggcgc gctggatgcc ttttactcct gtcaatatgg
     2821 ccgactggaa tatcgtacat tagactttaa aaaaataatt tgccagagtg attatcaagg
     2881 atgcgcagta atgaattatt gttcaataga tactccttat actcggatta ctgagcacaa
     2941 atatttttct ccgtgggaga gacatgaagc ttcaatatgt tatcaagaat atagtcggga
     3001 atgtgaagct ggtgatatac cctactatcc tgttcgcagg gcagataaaa tggatttact
     3061 gaataaatat ctgtcgcggg ctaaaaaaga aaaaatatta ctttcattgg tcgtcttggc
     3121 acttatcgtt atctcgatat ggacatcacg atagctgaag cattacagac ggcggacgta
     3181 tacttaacgt cgctatatga acaaaaagaa atgccagctt ttacagttac cgtttgatga
     3241 agtgtacagc gctaatcgta acttttaatc gtcttgaaaa attaaaaaaa agtgtgcgag
     3301 agactgttaa ggcgggtttt tcctctattg ttatcgttaa taatggctca agcgacggta
     3361 ccagggaatg gctttcttca ttaagtgaac ctggcatcac gatacttaat cttaaagata
     3421 atcttggtgg tgctggcgga tttaaagtag gtagtcaata tatatgctca tatagtaatg
     3481 ccgattgggt atttttttat gatgatgatg cttacccgga aattaatatt tta
//
LOCUS       DAJVBX010000286         3470 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.286, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000286 DAJVBX010000000
VERSION     DAJVBX010000286.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3470
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.286"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..1530)
                     /locus_tag="OPV72_004281"
     CDS             complement(<1..1530)
                     /locus_tag="OPV72_004281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraI domain-containing protein"
                     /protein_id="HCR9916416.1"
                     /translation="MFRKVKSWMEKKNFRQIEENKSGNAKKRLIPCTDGYFNPAAISD
                     LLQHERRQQWLRILWENSALPKERFERYFLLPLHGVVGLCQRLPASAQGKFAYTDGMV
                     DYVIQTTVFAVRLSKGYMLPRGASAEEQSAQSVSWSAVVYYAALFHSLGRLWNIEGEL
                     RSGAVWRPGLSVPEEPYRFRFKAEPDIAGAQVYGELIALRFLPEPVLQWLGKNPDILR
                     TLLAFISGRYSDAMDITDIVNEAIVHAGGIPLGFPIAQEEQTSELAEILNPAATVAPV
                     LRKGSSTTPPDVPVMVDGGQETTVLLSSLDSDAKPERGEGQPTAETDPDVLQVMSILG
                     GLTNTDTQSPEKEGVNTETDMVAGESFPEVAVALETSAAEEVINDTVTTECTGSSSGG
                     ISSLSSTELGDLFWSWLRDGLREGDIPVNTADACVHLTCGFVFISVPGVFFLFLKSHS
                     RSCSSGLKESGRKEQVQAAFEKMRKHRVSDSRRFWQCCLYEEPGGRGRYKKLTGYLIK
                     MS"
     gene            complement(1514..3025)
                     /locus_tag="OPV72_004282"
     CDS             complement(1514..3025)
                     /locus_tag="OPV72_004282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001120833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HCR9916417.1"
                     /translation="MPHTDTPEQAAVIAWKGERLVVCAFAGSGKTTTLRRYAEENPTE
                     RMLYIAYNRAIRDEAEQKFPFNVTCKTSHQLAWPTVGKHYSHRLINSLRLTYVARALN
                     SRNWLLARLTLDVLNRFICSAATDITPEHMPDPDDCKGLQPGQILFSAKKIWAMMSAR
                     QGDFPVTHDTYLKLYQLSKPNLSSRYTTLLFDEAQDANPVISAIVLNQTCRVVLVGDT
                     HQQIYRFRGADNAMQAPQLENSDRLWLTHSFRFGPEVAGVANRLLALKGETHQITGKG
                     GAGRVLLTMPRNFGHHAVLHRSVCGVIRTALHWSLAGRKVFWVGGMESYRIEDLLDLY
                     WFSIDMSERMRHDRLTREYRDYDEYLQIAEDTGDVEMKQGIFILEQFFPLPDRLNTLR
                     EQRVISESEADVTVCTAHRSKGLEWDRVKLHDDFLDILDPDMPESQRQDEINLMYVAA
                     TRARKVLITDPILHELLIQPRAEDIAGTSADKSGESEVSTENDKKGTEYVPES"
BASE COUNT          923 a          929 c          752 g          866 t
ORIGIN      
        1 tgacattttt atcagatacc ctgttaactt tttgtatctc cccctgcccc ctggctcttc
       61 ataaagacag cactgccaga atcgccggga atcactgacc cgatgctttc gcatcttctc
      121 aaatgccgcc tgcacctgct ccttcctccc gctttctttc agaccagaag aacaggaacg
      181 cgaatgtgat ttcaaaaaca gaaaaaaaac acccgggacg ctgataaata cgaagccaca
      241 agtcagatga acacaggcat cagcagtatt tactggtata tccccctcac gaagcccatc
      301 ccttagccag gaccagaaca aatctcccag ctccgttgag gaaagcgatg atatgccacc
      361 cgaggatgat ccagtgcatt cagtggtaac ggtgtcattg ataacctctt ctgctgctga
      421 agtctcaagt gcaaccgcga cttccggaaa cgattctcct gccaccatat cggtctctgt
      481 gttcacgcct tccttttcag gcgactgtgt gtcagtgttc gtcagccctc ccagaatcga
      541 catgacctga agaacatctg gatctgtttc agcagtaggc tgcccttccc cacgttcagg
      601 cttagcatca gaatcaaggg aagataaaag gacagtagtc tcctgccctc catcaaccat
      661 gacagggaca tcaggaggag ttgtagaaga acctttcctc aacacgggag ctactgtcgc
      721 ggcagggttt agtatctctg ctaattcaga agtctgctct tcctgtgcaa tgggaaaacc
      781 aagaggtatc cctccggcat gcacaatggc ctcattaacg atatccgtaa tatccattgc
      841 atcactgtaa cgtccgctta tgaaagccag caatgttctc agaatatcag ggtttttacc
      901 cagccactga agaaccggtt ctggcaaaaa tctgagagcg atcaattcac cataaacctg
      961 agcacctgct atatcgggtt ctgctttaaa acgaaaacga taaggttctt ccggaacact
     1021 taatcccggg cgccatacag caccactacg gagctcgcct tcaatattcc ataagcgccc
     1081 caacgagtgg aataatgcag cgtaataaac gacagcactc cagctgactg actgcgcgga
     1141 ttgttcctct gcagatgcac ctcggggcag catatatcct tttgataaac gtacggcaaa
     1201 gaccgtcgtc tgtatgacgt aatccaccat gccgtctgta taggcaaatt ttccctgagc
     1261 cgaagccggg agtctctgac ataaacccac aacgccgtgt aaagggagta aaaaataacg
     1321 ttcaaaacgc tctttaggta gcgcgctgtt ctcccacaaa atccttaacc attgctgccg
     1381 tcgttcatgc tgtaacaaat ctgaaatggc cgcagggtta aaatatccat ccgtacaggg
     1441 aataagtctc ttcttcgcat ttcccgattt attttcttct atctgtctga agtttttctt
     1501 ctccatccat gacttaactt tccggaacat attcagtccc ttttttatcg ttttctgtac
     1561 tcacttctga ctcacccgat ttatccgcag aagttccggc tatatcttca gcccggggct
     1621 ggatcagaag ctcgtgcaat atcggatcgg ttataagcac tttacgcgcc cgggtggctg
     1681 ccacatacat gaggttaatt tcatcctgcc gctgactttc cggcatgtca ggatccagaa
     1741 tatcgagaaa gtcatcatgt aacttcaccc tgtcccattc gagcccctta ctcctgtgtg
     1801 ctgtacatac cgtcacatca gcttcagatt cactgatgac gcgttgctca cgtaacgtat
     1861 tcagtctgtc cggtaacgga aaaaactgtt caagaataaa tatcccctgc ttcatctcca
     1921 catcaccggt atcttcggct atctgcagat attcatcata gtcccggtat tcacgggtca
     1981 gcctgtcgtg tcgcatacgc tccgacatat caattgagaa ccagtacaga tccagtaaat
     2041 cctcaattct gtagctttcc ataccaccaa cccagaatac tttcctgcca gccagcgacc
     2101 agtgcagtgc cgtccggatg acaccacaga cagatcggtg aagaacagca tgatggccaa
     2161 aattccgcgg cattgtgagc agaacacggc ctgcgccccc ctttccagtt atctgatgcg
     2221 tttcgccctt cagggccagc agcctgttgg ccaccccggc tacctccgga ccgaagcgaa
     2281 agctgtgggt tagccaaaga cggtctgagt tctccagttg cggagcctgc atggcattat
     2341 ccgccccacg aaagcggtag atttgctgat gagtatctcc aaccagaact acccggcagg
     2401 tctggttgag cacaatggcg ctgatgacag gattggcatc ctgagcttca tcaaacaata
     2461 acgtggtata gcgggaagaa agattcggtt tgctcaactg gtaaagcttt agataagtat
     2521 catgggtgac cggaaaatcc ccctgacggg ccgacatcat tgcccagatt ttctttgctg
     2581 aaaacaggat ttgacctggt tgtagcccct tacagtcgtc aggatcaggc atgtgttcag
     2641 gcgtaatatc ggtggccgcg ctgcatataa agcgattcag aacatcaagc gtcagtctgg
     2701 ccagcaacca gttgcgggag tttagcgccc gggcgacata ggtcagtcgt agtgaattaa
     2761 tcagacgatg actgtaatgt ttcccgaccg tcggccaggc cagttgatgc gatgttttgc
     2821 aggtaacgtt gaaggggaat ttctgctccg cctcatcccg aatggcacgg ttataagcaa
     2881 tatagagcat tcgttccgtt ggattttcct cagcataacg acgaagtgtg gtggttttgc
     2941 cactcccggc aaaagcacag acaaccagac gttcgccctt ccatgcgatg acagcagcct
     3001 gttcaggagt atcagtgtgg ggcataatcg ggctccggat aaaagcattt tgctcatcct
     3061 gagaacccgc cagactgtta tccagtgcaa tttataaatc caaaaaaaag aattctgcaa
     3121 accagccctg taccatcaag ttcatatcct cagcggagga aatgcgtgaa atccagcgca
     3181 acacacggag tatcacccac tacccaggca tcatgattct cagaaacctc aaatgcttcg
     3241 ccggcatgaa taaggtattc atttccgaag cagtcacgca ccatcatttc accggaaatt
     3301 ataaaaccag tatgacgttc tgacggtttt ccggtcatta ttaatgggtg actctaatgc
     3361 aaacatctag cgagaaaata ttttgtagac atcgtcaacg gaaaagttaa ctaacaatag
     3421 tcattatcca tatctttaat ttgaaatgga aacagggcaa agagtaatta
//
LOCUS       DAJVBX010000287         3447 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.287, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000287 DAJVBX010000000
VERSION     DAJVBX010000287.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3447
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.287"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            211..2127
                     /gene="dnaK"
                     /locus_tag="OPV72_004283"
     CDS             211..2127
                     /gene="dnaK"
                     /locus_tag="OPV72_004283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001737966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HCR9916418.1"
                     /translation="MGKIIGIDLGTTNSCVAIMDGTQARVLENAEGDRTTPSIIAYTQ
                     DGETLVGQPAKRQAVTNPQNTLFAIKRLIGRRFQDEEVQRDVSIMPYKIIGADNGDAW
                     LDVKGQKMAPPQISAEVLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRI
                     AGLEVKRIINEPTAAALAYGLDKEVGNRTIAVYDLGGGTFDISIIEIDEVDGEKTFEV
                     LATNGDTHLGGEDFDTRLINYLVDEFKKDQGIDLRNDPLAMQRLKEAAEKAKIELSSA
                     QQTDVNLPYITADATGPKHMNIKVTRAKLESLVEDLVNRSIEPLKVALQDAGLSVSDI
                     NDVILVGGQTRMPMVQKKVAEFFGKEPRKDVNPDEAVAIGAAVQGGVLTGDVKDVLLL
                     DVTPLSLGIETMGGVMTPLITKNTTIPTKHSQVFSTAEDNQSAVTIHVLQGERKRASD
                     NKSLGQFNLDGINPAPRGMPQIEVTFDIDADGILHVSAKDKNSGKEQKITIKASSGLN
                     EEEIQKMVRDAEANAESDRKFEELVQTRNQGDHLLHSTRKQVEEAGDKLPADDKTAIE
                     SALSALETALKGEDKAAIEAKMQELAQVSQKLMEIAQQQHAQQQAGSADASANNAKDD
                     DVVDAEFEEVKDKK"
     gene            2213..3352
                     /gene="dnaJ"
                     /locus_tag="OPV72_004284"
     CDS             2213..3352
                     /gene="dnaJ"
                     /locus_tag="OPV72_004284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HCR9916419.1"
                     /translation="MAKRDYYEILGVSKTAEEREIKKAYKRLAMKYHPDRNQGDKEAE
                     AKFKEIKEAYEVLTDAQKRAAYDQYGHAAFEQGGMGGGFGGGFNGGADFSDIFGDVFG
                     DIFGGGRGRQRAARGADLRYNMDLTLEEAVRGVTKEIRIPTLEECDVCHGSGAKAGTQ
                     PQTCPTCHGSGQVQMRQGFFAVQQTCPHCQGRGTLIKDPCHKCHGHGRVEKSKTLSVK
                     IPAGVDTGDRIRLAGEGEAGEHGAPAGDLYVQVQVKQHPIFEREGNNLYCEVPINFAM
                     AALGGEIEVPTLDGRVMLKVPSETQTGKLFRMRGKGVKSVRGGAQGDLLCRVVVETPV
                     GLSEKQKQLLKDLQESFGGPTGEKNSPRSKSFFDGVKKFFDDLTR"
BASE COUNT          894 a          838 c          974 g          741 t
ORIGIN      
        1 tgtttacctg tctggttttc catcgcgccc tctcgtcaat aaaaaatttt ttcatctccc
       61 ccttgatgac gtgggttacg accccatctt gtagtcaacc gcagtggtga gtctgaaaaa
      121 aaacgattca gggtagttga aaccgcacgt ttcgccctta ttacagattc acaaccacat
      181 gatgaccgaa tttttagtgg agacgtttag atgggtaaaa ttattggtat cgacctgggt
      241 actaccaact cttgtgtagc gattatggat ggaacgcagg cacgcgtgct ggagaacgcc
      301 gagggcgatc gcactacgcc ttctatcatt gcttataccc aggatggtga aactctggtt
      361 ggtcagccgg ctaaacgtca ggcagtgaca aacccgcaaa acaccctgtt tgcgattaaa
      421 cgcctgattg gccgccgctt ccaggacgaa gaagttcaac gtgacgtttc tatcatgccg
      481 tacaaaatca tcggcgccga caacggcgac gcatggcttg atgtgaaagg tcagaaaatg
      541 gcgccgccgc agatttctgc cgaagtgctg aagaaaatga agaaaacggc tgaagattat
      601 ctgggcgaac cggtaactga agcggttatc accgtaccgg cttactttaa cgatgcgcag
      661 cgtcaggcta ccaaagatgc tggtcgtatc gcggggctgg aagttaaacg tatcatcaac
      721 gaaccgactg ccgcagcgct ggcttacggt ctggataaag aagtcggcaa ccgtactatc
      781 gcggtttacg acctcggtgg tggtactttc gatatctcta ttatcgaaat cgacgaagtt
      841 gatggcgaaa aaacctttga agttctggca accaacggtg atacccacct gggtggtgaa
      901 gacttcgata cccgcctgat caactacctc gttgacgagt ttaagaaaga tcagggcatc
      961 gacctgcgta acgatccgct ggccatgcag cgcctgaaag aagccgcaga aaaagccaaa
     1021 atcgagctgt cttctgcgca gcagaccgac gtgaacctgc cgtacattac cgcagatgcc
     1081 accggtccga aacacatgaa catcaaagtg acccgtgcga aactggaaag cctggttgaa
     1141 gatctggtga accgttctat cgagccgctg aaagtcgcac tgcaggacgc tggcctgtcc
     1201 gtgtctgata tcaacgacgt gatcctcgtc ggcggtcaga cccgtatgcc aatggtgcag
     1261 aaaaaagtgg ctgagttctt cggtaaagag ccgcgtaaag acgttaaccc ggacgaagct
     1321 gtggctatcg gcgcagcggt acagggcggc gtattgaccg gtgatgtgaa agacgtactg
     1381 ctgctggacg ttaccccgct gtctctgggt atcgaaacga tgggtggcgt gatgactccg
     1441 cttatcacca aaaacaccac catcccgacc aagcacagcc aggtgttctc tactgcggaa
     1501 gacaaccagt ctgcggtaac catccatgtg ctgcagggtg agcgtaaacg tgcgtctgat
     1561 aacaaatctc tgggtcagtt caacctggat ggcatcaacc cggcgccgcg cggtatgccg
     1621 cagatcgaag tcaccttcga tatcgatgct gacggtatcc tgcacgtctc cgcgaaagat
     1681 aaaaatagcg gtaaagagca gaagatcact atcaaggcgt cttctggtct gaacgaggaa
     1741 gaaattcaga aaatggttcg cgatgcagaa gcgaacgctg aatccgaccg taagttcgaa
     1801 gagctggttc agacccgtaa ccagggtgac catctgctgc acagcacccg taagcaggtt
     1861 gaagaagcag gcgataaact gccggctgat gacaaaaccg ctatcgagtc tgcgctgagc
     1921 gcgctggaaa ctgccctgaa aggcgaagat aaagccgcta tcgaagcgaa aatgcaggag
     1981 ctggcgcagg tttcccagaa actgatggaa atcgctcagc agcaacatgc gcagcagcag
     2041 gctggctccg ccgacgcttc tgcaaacaat gcgaaagatg acgacgttgt cgacgctgag
     2101 tttgaagaag taaaagataa aaaataatcg ccctttgaac gggtaattac tggcacgggc
     2161 gaagaggttt cctctccgcc cgtgtatgca tgttaagggc agataaaaag agatggcgaa
     2221 aagagattac tacgagattt taggcgtttc caaaacagcg gaagagcgtg aaatcaaaaa
     2281 ggcgtataag cgcctggcca tgaaatatca tccggaccgc aatcagggtg ataaagaggc
     2341 cgaagctaag tttaaagaga ttaaagaagc ctacgaagtg ctgaccgatg cgcaaaaacg
     2401 cgcagcctac gatcagtatg gtcacgccgc gtttgaacaa ggcgggatgg gcggcggatt
     2461 tggcggcggc tttaatggcg gcgctgattt cagtgatatc tttggtgacg tttttggcga
     2521 tatctttggc ggcgggcgtg gtcgccaacg tgcggcgcgt ggggctgatt tgcgttataa
     2581 catggatctc accctggaag aagcggtgcg tggcgtgacc aaagagatcc gtattccgac
     2641 gctggaggag tgcgacgttt gccacggcag cggcgcgaaa gctggtacgc aaccgcaaac
     2701 ctgtccgacc tgtcatggtt ctggtcaggt acagatgcgc cagggattct ttgctgtaca
     2761 gcagacctgc ccacactgtc agggccgcgg tacgctgatc aaagatccgt gccataaatg
     2821 tcacggtcat gggcgtgttg aaaagagtaa aactctgtcc gttaaaatcc cggcgggcgt
     2881 ggataccggc gatcgtattc gtctggcagg cgagggcgaa gcgggcgagc atggcgcacc
     2941 ggcaggcgac ttgtacgttc aggtccaggt gaaacaacac cctattttcg agcgtgaagg
     3001 caataatctt tattgcgaag tgccgatcaa ctttgcgatg gcggcgctcg gcggtgaaat
     3061 tgaagtgccg acgttagatg gtcgcgtgat gctgaaagta ccgagcgaaa cacaaacggg
     3121 caagctgttc cgtatgcgcg gcaaaggcgt gaagtccgta cgcggtggcg cgcagggcga
     3181 tttgctgtgc cgtgtggtag ttgaaacgcc ggtcggtctg agcgaaaaac agaagcaatt
     3241 gctaaaagat cttcaggaaa gttttggcgg cccgacggga gagaaaaaca gcccgcgttc
     3301 aaaaagcttc tttgacggcg tgaaaaaatt ctttgacgat ttgactcgct aacctttttc
     3361 ccgttgtatt tttcttcagc ccgggtgtat gtatatccgg gctttttttc tgcctgtacg
     3421 cgcccaggct tctgctaaac gcatcgt
//
LOCUS       DAJVBX010000288         3433 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.288, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000288 DAJVBX010000000
VERSION     DAJVBX010000288.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3433
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.288"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(64..384)
                     /locus_tag="OPV72_004285"
     CDS             complement(64..384)
                     /locus_tag="OPV72_004285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010989117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916420.1"
                     /translation="MATSNYNINGQTGTADALSGMNTNNSPFLHTPADGSRKFTTFEV
                     GHDRAFDSEVKIFEHIANKFPTTAKGRIDLYSELKVCPSCSEVITQFKAMYPNIEVNV
                     TWGG"
     gene            complement(469..2973)
                     /locus_tag="OPV72_004286"
                     /pseudo
     CDS             complement(469..2973)
                     /locus_tag="OPV72_004286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001529574.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat protein"
     gene            2973..3296
                     /locus_tag="OPV72_004287"
     CDS             2973..3296
                     /locus_tag="OPV72_004287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001651551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system SymE family toxin"
                     /protein_id="HCR9916421.1"
                     /translation="MPDFTHCEFYSRVEGRSVRLCGEWMPQAGFINGVPVKIRVMKDC
                     IVITLQNTRELLGCIEGMGVTYINQRNVKAWLKDFPGALNDTGDIPVMSRDLQCITTN
                     CRFAH"
BASE COUNT          622 a         1153 c          818 g          840 t
ORIGIN      
        1 ttttttgacg ttatcgatgc aattaacttc ttaatttcaa tcaaaaaagc tcgctgttcc
       61 atattaccct ccccatgtca cattaacttc aatattagga tacattgctt tgaattgagt
      121 tataacctct gaacatgagg ggcatacttt taattccgag tatagatcaa tacgaccttt
      181 tgccgttgtt ggaaatttat tggctatatg ttcaaatatt ttaacttcag aatcgaaagc
      241 cctgtcatgc cccacttcga aggtagtgaa ctttcgactt ccgtctgctg gagtatgtaa
      301 aaatggtgaa ttattcgtat tcatgccact aagtgcatca gccgttcctg tttgaccatt
      361 aatattataa ttggatgttg caatatttcg ttttccacct acctagccag tgcttctata
      421 attcctggcc ctttctgccg gagaaccttt accagcaaat tttttacata aacctagcgg
      481 atctatataa cttagcggat taggcgcata ttggtagagg tttattccac ccgctaaccc
      541 tatcggatcg cccgatataa acttcccgat atccggatca taaaatctgt acaaattgta
      601 atgcagcccc gtttccctgt ccagatattg cccctggaaa cgcaggttct gctgtacggg
      661 ccgggtttct ttttcatgcg tcaggttccc ccatacctga tagcccgctt cccagacaat
      721 attgcccccg ccgtccgtca tctcctccgg cgcgccgttt acgtccgtat ggtaatacag
      781 cacctcatcc gcttcgcccg gcgccgccct gtccacccgc gccagcggct cgtggctccc
      841 ccggtcgctg tagatataca ggctgctgct tcttcccagc ctgcactcct gtgccagccg
      901 cattccgtcc cataaaaacg tcgtccggtt atacggcttt ccttccgcgt ccagctcgtg
      961 cttctccacc cgcctgcccg gcgcgtcgta cacgtacccg taacgccgta cggtgccccc
     1021 ccgggtgacc gccacttccg tcagccggtg ctccgcgtcc cagcggtagt gctgcgtgcc
     1081 gttgcggccc cgcttttcca ccacccggcc atattcatcg taacggtaat gcagcccgcg
     1141 atatgacgtt atccggttga acggcaccac gctgcctgca cccgcctgcg cggtctctcc
     1201 ctgccgcctg tccagcaggt tcgccgccgc gtcgtactgc cagctgtcca ggtatgcctc
     1261 attccggcac gccgtgatgc gccccgtcgt gtcgtaaaaa taatccgtca ccccctgccg
     1321 gctgtgccgc tttttcagca gctcatcctg gccgctgtac gcatattccc ggtcaataaa
     1381 cgtctccggc accacaccgc gcattccttt acaggtcagt ttccgcgtta accggcccgt
     1441 ccggtcgtac atccgccgca tgtccagccg cccctggctc cgctgcacct cacggtgcag
     1501 gtggtcgcgc gtgaactcgc tgatgacatc acgccccagg ttgatttgct ggagatgtcc
     1561 gctcccgtag tacaggtacc gcagcgtccg cccgtccggc atctgcgttt ctgtgcggtt
     1621 gccctgaaca tcgtaccggt gctgcagcac gccctgcgcc gtctcctcgc tcagcaggtt
     1681 acccgcactg tcgtagctga accggataac ttccggctct ccgccttccg ccgcatcatg
     1741 ccgcctgcgg cggatttcca gcagacggtc cgccgcgtcg taccggtatt ccgtgcgcgt
     1801 ctccggcgtg attttcgccg tcagcctccc cgccgcatca cgctccagac cgtggcggat
     1861 ttctcccccg cgctccccgc cgtatatcac tgccgtcacc gcattcagcg cgttataccc
     1921 gtatgcccgg cggctgccgc cggggtccgt ctgttccgtc acccggtcca gaacatcgta
     1981 ccggaaccgg tagctttccc cgttctcgtt cgtgagcgtg gtcagccgcc cgtaagcgtc
     2041 gtactcatac gccgtcctgc gacccgtcgc atccgtctgc ctgcgcaccc gcccctggcc
     2101 gtcccgctgc cagcgtgtta tttgccccgc cgggctcgta tatttcacca gccgtcccgc
     2161 cgcatccggc tggtaacgct ccgtacgccc gtccgcgaac atgacctccg tcagatgtcc
     2221 gttgccgtca tagctgtaac gcgtactgtt actctccgcg tccgtcaccc tttccagccg
     2281 cgtgcgttca tcataaaacc atgccgtctg cgagccagaa cagtccgtgt ggcgcataag
     2341 ctgtccgtct tcgttccact gcaggtattt atctccgccc cgcgcgtcgg ttatccgcac
     2401 cacctggccg tgccggtcat acccgtatac cgtgcgctgg tgcagcgggt cgctgaccgc
     2461 ctgcaggttg ccccgctcat catactcata acgccacgcc acccccgcgg catccacctc
     2521 cgtttccggc tggtgccaca ccgggtgcca ctgcgtctgc tcaacccggc ccagcgggtc
     2581 atgcgtctcc gtcaggtggc cgagacggtc atagacataa cgccatttgc caccctgcgc
     2641 gtccgtcatc cccagcagta accgctcttc atcgctccag cggaaagtgg tcatctgccc
     2701 ggcctcgtcc cggtacgccg tcaccaggcc ctgcgcatcc caccagtggc agcgcgtacg
     2761 ccccatgcta tccgtcacgc acagcgaacg ttctgccaga ttccagtcca gacggtactg
     2821 ctcgccgctg tccgtatgat ggcccgtcac ccgccacgcc gcatcgtccg ggccttcaaa
     2881 ccacgcccag gtgtagtaat accgttcgcc gcccggctcc cggtgcatcg tcatgcagtc
     2941 gttgtcgtcg tacgcaaact cgcgctgata ctgtgccgga ttttacccac tgtgagttct
     3001 attcacgggt tgagggacgt tcagttcgtt tatgcggtga atggatgccg caggccgggt
     3061 ttattaacgg agtgcccgtt aaaattcggg tgatgaaaga ctgcatcgtg atcacgctgc
     3121 aaaatacccg tgaactgttg ggctgtattg aagggatggg cgtgacctat atcaaccagc
     3181 gaaacgttaa agcatggctg aaagattttc ccggtgcgct gaatgacacc ggggatattc
     3241 cggtgatgag tcgggatctt cagtgtatta ctaccaattg ccggtttgct cactaacaac
     3301 agaaaaaaca acatcgcggt catcaaatat cccgtgtcag tctatggatt catttccatt
     3361 tcagtgtcat caacatgcag cccgacaatc ccggcgtcct gtattgcatc gatcagtctg
     3421 tcagaaaaaa ata
//
LOCUS       DAJVBX010000289         3352 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.289, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000289 DAJVBX010000000
VERSION     DAJVBX010000289.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3352
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.289"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(104..865)
                     /gene="kduD"
                     /locus_tag="OPV72_004288"
     CDS             complement(104..865)
                     /gene="kduD"
                     /locus_tag="OPV72_004288"
                     /EC_number="1.1.1.127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase
                     KduD"
                     /protein_id="HCR9916422.1"
                     /translation="MILNAFSLEGKVAVVTGCDTGLGQGMALGLAEAGCDIVGINIVE
                     PTETIARVTALGRRFLSLTADLRQIDGIPALLERAVAEYGHIDILVNNAGLIRREDAI
                     DFTEKDWDDVMNLNIKSVFFMSQAAAKYFIAQGNGGKIINIASMLSFQGGIRVPSYTA
                     SKSGVMGITRLMANEWAKHNINVNAIAPGYMSTNNTQQLRADAQRSAEILDRIPAGRW
                     GLPGDLMGPVVFLASSAADYINGYTIAVDGGWLAR"
     gene            complement(920..1756)
                     /gene="kduI"
                     /locus_tag="OPV72_004289"
     CDS             complement(920..1756)
                     /gene="kduI"
                     /locus_tag="OPV72_004289"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HCR9916423.1"
                     /translation="MDVRQSIHSEHAKTLDTQALRREFLIENIFVADEYTMVYSHIDR
                     IIVGGIMPVSHPVEIGGEVGKQLGVSRLLDRRELGVINIGGAGAIIVDGQRHDIGHRD
                     ALYIGKGAKELVFVSNEASRPAKFYYNCAPAHTAYPTKKVSPADVAPVTLGDNLTSNR
                     RTINKYFVPDVLETCQLSMGLTELAPGNLWNTMPCHTHERRMEVYLYFNMEEDSCVFH
                     MMGQPQETRHIVMRNEQAVISPSWSIHSGVGTKAYTFIWGMVGENQVFDDMDHVAVQD
                     LR"
     gene            complement(2186..3352)
                     /locus_tag="OPV72_004290"
     CDS             complement(2186..3352)
                     /locus_tag="OPV72_004290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001499677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HCR9916424.1"
                     /translation="MIVGALRTPIGCFQGTLARHSAVELGSMVVKALIERTGVDANAI
                     DEVILGQVLTAGAGQNPARQSAIKGGLPTTVSAITINDVCGSGLKALHLATQAIQCGE
                     ADIVIAGGQENMSRAPHVLNDSRTGALPDADNLVDSLVHDGLWDAFNDYHIGVTAENL
                     AREYGISRELQDAYALSSQQKARAAIDTGRFKDEIVPIVTQRNGQTAIVDTDEQPRAD
                     ASAEGLALLHPAFDSLGSVTAGNASSINDGAAAVMMMSETKAQALGLPVLARIRAFAS
                     VGVDPALMGIAPVYATRRCLERAGWQLTEVDLIEANEAFAAQALSVGKMLEWDERRVN
                     VNGGAIALGHPIGASGCRILVSLVHEMVKRDARKGLATLCIGGGQGVALTIERD"
BASE COUNT          800 a          954 c          806 g          792 t
ORIGIN      
        1 tatgctaatg agatcataaa aaaaccctgt acgaggacag ggctttatca gttttttcgg
       61 ccaaagagtc gattttccca gaaacgcatt tgtcagtagc ggattaacgc gccagccaac
      121 cgccatctac cgctatggta tagccgttaa tataatcagc ggcgctggat gccaggaaga
      181 ctaccggccc cattaaatcg cccggtagcc cccaacgtcc agccggaata cggtcgagaa
      241 tttcggcgct acgttgtgca tcagcgcgca attgctgggt attattcgtg gacatatagc
      301 ccggcgcgat ggcgtttaca ttgatattgt gtttcgccca ctcgttcgcc atcagacgcg
      361 ttattcccat tacgccgctt ttcgacgcgg tataagacgg aacacgaatg ccgccctgga
      421 aggaaagcat agacgcgata ttaataattt tgccgccgtt gccctgggca ataaaatatt
      481 ttgccgccgc ctgagacata aagaacacgc tcttgatgtt caggttcatg acgtcatccc
      541 agtctttttc cgtgaaatca atcgcatctt cacgacggat caaacccgcg ttattcacca
      601 gaatatcaat atgaccgtat tccgccaccg cccgttccag tagcgccgga ataccatcga
      661 tttgacgcag atcggctgtc aggcttaaaa aacgtcgtcc cagagcggtg acgcgcgcaa
      721 tagtttccgt cggttcaaca atgttaatac cgacaatgtc acagcccgct tccgccagcc
      781 ctaacgccat cccctgtccc aatccggtat cgcaccccgt cacaaccgcg actttacctt
      841 caagagaaaa tgcattcaaa atcattgtta atccttattt ttgtcatgcc tgtcacacag
      901 gcgttatcac cggtcgcgac tagcgcagat cttgtaccgc aacgtgatcc atgtcatcga
      961 agacctgatt ttctcccacc atgccccaaa taaacgtata ggctttggtg ccaacgccgg
     1021 aatgtattga ccagcttggg gaaataaccg cctgttcatt acgcatcaca atatgacggg
     1081 tttcctgagg ctgccccatc atatggaaaa cgcaactgtc ctcttccata ttgaaataga
     1141 ggtaaacttc catacggcgc tcatgggtat ggcatggcat ggtgttccat agattgccgg
     1201 gcgccagttc ggtgagtccc atactgagct gacaggtttc cagtacatcc ggtacgaagt
     1261 atttattgat ggtgcgacgg ttactggtga ggttatcgcc taaggtgacg ggcgcaacgt
     1321 cggcaggcga cacttttttc gtcggataag cggtgtgcgc tggcgcgcag ttgtaataaa
     1381 acttcgccgg tctgctcgcc tcattgctga cgaagaccag ctctttcgcc cctttaccaa
     1441 tatacagagc atcacgatga ccaatgtcat ggcgctgccc gtcaacgata atggcgcccg
     1501 cgccgccaat attaatgacg cccagctcgc ggcggtccag taatcgggaa acgccaagct
     1561 gtttacctac ttctccgccg atttcaacgg gatggctgac gggcataatg ccgccgacaa
     1621 taatacggtc gatatggctg tagaccatcg tatattcatc agcgacaaaa atattttcta
     1681 ttaaaaactc gcgtcgcagc gcctgggtgt ccagcgtttt agcgtgctcg ctatggatac
     1741 tttgccttac gtccactttt ccctccaatg ataaatcgat cgcaacggca taaaatcaaa
     1801 acactgtttt gatttattta acggcatcat agtcgcctgg ataaaggttt tcaacaataa
     1861 ataaaacaac gtttcatttt tatgtctggt tatttttaaa actgctgtag cgatcacgat
     1921 cggcgctaaa acttacgcat ttgtctgatt ttcagacatg cgcgccagat gctgtatgcg
     1981 gttacccaga taaaaattgg agcttgtttt agaacgaggt ctgatgtgcg aattgaatta
     2041 aaagcggtac gcgtctgcaa tgcccgccgc ggcaagaagt tctgcgctat aacgaaaaag
     2101 gggggtctgt cactggcttt gccctcgtga tagagggctt tttatgacgg aatactgaag
     2161 caggaaaagg gtggctggcg taggatcagt cgcgttcaat ggttaaagca acgccctggc
     2221 cgccaccgat acacagcgtc gccagacctt ttcgcgcgtc gcgtttaacc atttcgtgca
     2281 ccagtgaaac cagaattcga caaccggaag cgccaatggg atgccccagc gcaatcgcgc
     2341 cgccattaac gtttacccgt cgctcatccc attccagcat ttttcctacc gacaacgcct
     2401 gggcggcaaa cgcttcgttg gcttcgataa ggtcgacctc cgtcagttgc cagccggcac
     2461 gctccagaca gcgccgggta gcatataccg gcgcaatccc cattagcgca ggatcgacgc
     2521 cgacgctggc aaacgcgcgg atgcgcgcca gcaccggcag ccccagcgcc tgggctttcg
     2581 tctcgctcat catcatcacc gcggcggcgc catcgttgat tgaagaggca ttacccgccg
     2641 tcaccgaacc taaactatca aacgccggat gcagcagggc taacccctcc gcactggcgt
     2701 cggcccgcgg ttgttcatcc gtatcgacaa ttgcggtctg cccattacgt tgcgtgacga
     2761 tggggacaat ctcatcttta aaacgtccgg tatcaatcgc ggccctggct ttttgttgcg
     2821 aactgagcgc ataagcatcc tgtaactcgc ggctgatgcc atattcccgc gccaggtttt
     2881 ctgccgtcac gccaatgtga taatcgttga aggcatccca taagccatca tgtaccagac
     2941 tatccaccag attgtcggca tcaggcaacg cgccggtacg gctgtcattg aggacatgcg
     3001 gcgcacggct catattctcc tgcccgcccg caataacaat gtccgcttcg ccgcactgaa
     3061 tagcctgcgt cgccaggtgc aacgctttta aaccggaacc acaaacgtca ttaatggtaa
     3121 tagcggaaac ggtagtcggc agccctcctt tgatggctga ctggcgcgcc ggattctgcc
     3181 cggcgccagc cgtcagtacc tgaccgagga tgacctcatc gatagcatta gcgtccacgc
     3241 cggtgcgctc aattaacgct tttacgacca tactccccag ctcgacggcg gaatgacggg
     3301 ccagcgttcc ctgaaaacag ccgatgggtg tccgtaaagc ccccactatc ac
//
LOCUS       DAJVBX010000290         3332 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.290, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000290 DAJVBX010000000
VERSION     DAJVBX010000290.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3332)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3332)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3332
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.290"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            110..967
                     /gene="focA"
                     /locus_tag="OPV72_004291"
     CDS             110..967
                     /gene="focA"
                     /locus_tag="OPV72_004291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate transporter FocA"
                     /protein_id="HCR9916425.1"
                     /translation="MKADNPFDLLLPAAMAKVAEEAGVYKATKHPLKTFYLAITAGVF
                     ISIAFVFYITATTGTGAMPYGMAKLIGGICFSLGLILCVICGADLFTSTVLIVVAKAS
                     GRITWGQLAKNWLNVYFGNLIGALLFVLLMWLSGEYMTANGQWGLNVLQTADHKMHHT
                     FIEAVCLGILANLMVCLAVWMSYSGRSLMDKAFIMVLPVAMFVASGFEHSIANMFMIP
                     MGIVIRDFATPEFWTAVGSSPESFSHLTVMSFITDNLIPVTIGNIIGGGLLVGLTYWV
                     IYLRGNEHH"
     gene            1027..3309
                     /gene="pflB"
                     /locus_tag="OPV72_004292"
     CDS             1027..3309
                     /gene="pflB"
                     /locus_tag="OPV72_004292"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HCR9916426.1"
                     /translation="MSELNEKLATAWEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFL
                     AGATDATTKLWDSVMEGVKQENRTHAPVDFDTSVASTITSHDAGYINKALEKIVGLQT
                     EAPLKRAIIPFGGIKMVEGSCKAYNRELDPMIKKIFTEYRKTHNQGVFDVYTPDILRC
                     RKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKFAQFTSLQSDLENGVNLEATI
                     RLREEIAEQHRALGQIKEMAAKYGCDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMS
                     FGRVSTFLDAYIERDLKAGKITEQDAQEMIDHLVMKLRMVRFLRTPEYDELFSGDPIW
                     ATESIGGMGVDGRTLVTKNSFRFLNTLYTMGPSPEPNITVLWSEKLPLNFKKFAAKVS
                     IDTSSLQYENDDLMRPDFNNDDYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGG
                     VDEKLKMQVGPKSEPIKGDVLNFDEVMDRMDHFMDWLAKQYVTALNVIHYMHDKYSYE
                     ASLMALHDRDVIRTMACGIAGLSVAADSLSAIKYAKVKPIRDEDGLAIDFEIEGEYPQ
                     FGNNDARVDDMAVDLVERFMKKIQKLTTYRGAIPTQSVLTITSNVVYGKKTGNTPDGR
                     RAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVR
                     KTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMEHPEKYPQLTIRVSGYAVRF
                     NSLTKEQQQDVITRTFTQTM"
BASE COUNT          823 a          845 c          829 g          835 t
ORIGIN      
        1 ccatgcgact tacgggccta taagccaggc gagatatgat ctatatcaaa ttctcatcta
       61 taatgctttg ttagtatctc gtcgccgact taataaagag agagttagtg tgaaagctga
      121 caaccctttt gaccttttac tccctgcagc aatggccaaa gtggctgaag aagcaggcgt
      181 ctataaagca acgaaacatc cgcttaagac tttctatctg gcgattaccg ccggcgtatt
      241 catttcaatt gcctttgttt tttatattac tgcgacaacc ggtactggcg cgatgcctta
      301 tggcatggcg aaacttatcg ggggtatctg tttctctttg ggactgattc tctgtgttat
      361 ttgcggcgct gatcttttca cctctactgt tctgatcgtt gtagctaaag ctagcggtcg
      421 catcacctgg ggacaactgg ctaaaaactg gttaaacgtc tattttggta acctgattgg
      481 cgctctgctt ttcgtgttac tgatgtggct ttccggcgag tatatgactg ccaacggtca
      541 atggggactt aacgtcctgc aaaccgccga ccacaaaatg caccacactt ttattgaagc
      601 tgtctgcctc ggtattctgg cgaacctgat ggtttgtctg gccgtgtgga tgagctactc
      661 aggtcgtagc ctgatggaca aagcgttcat catggtactg cccgtcgcca tgtttgtcgc
      721 cagcggtttt gagcacagta tcgcaaacat gtttatgatt cctatgggta ttgtaatacg
      781 cgatttcgct acaccggagt tttggaccgc ggttggttcg tctccggaaa gtttttctca
      841 cctgaccgtg atgagcttca tcactgataa cctgattccg gtcacgatcg gtaatattat
      901 cggcggcggt ttgttggtcg ggttgacata ctgggtcatt tacctgcgtg gtaacgagca
      961 tcattaatct gttgatgtcc attacacgca gtaaataaaa aatccactta agaaggtagg
     1021 tgttacatgt ccgagcttaa tgaaaagtta gccacagcct gggaaggttt taccaaaggt
     1081 gactggcaga atgaagtaaa cgtccgtgac ttcattcaga aaaactacac tccgtatgag
     1141 ggtgacgagt ccttcctggc tggcgctact gacgcgacca ccaagctgtg ggacagcgta
     1201 atggaaggcg ttaaacagga aaaccgcact cacgcgcctg ttgactttga cacctccgtt
     1261 gcttccacca tcacttctca cgacgctggc tacatcaaca aagcgcttga gaaaattgtt
     1321 ggtctgcaga ctgaagctcc gctgaaacgt gcgattatcc cgtttggcgg catcaaaatg
     1381 gttgaaggtt cctgcaaagc gtacaatcgc gagctggacc caatgatcaa aaaaatcttc
     1441 accgaatacc gtaagaccca caaccagggc gtattcgacg tttatactcc ggacatcctg
     1501 cgttgccgta agtccggcgt gctgaccggt ctgccggatg cgtatggccg tggccgtatc
     1561 atcggtgact accgtcgcgt agcgctgtac ggtatcgact acctgatgaa agacaaattc
     1621 gcgcagttta cgtctctgca atccgatctg gaaaacggcg taaatctgga agcgactatc
     1681 cgtctgcgtg aagaaatcgc tgaacagcac cgcgctctgg gtcagatcaa agaaatggca
     1741 gctaaatacg gctgcgatat ctctggcccg gcgactaacg ctcaggaagc aatccagtgg
     1801 acttacttcg gttacttggc tgcggttaaa tctcagaacg gcgcagcaat gtccttcggt
     1861 cgtgtatcca ccttcctgga tgcgtacatc gaacgtgacc tgaaagcagg caaaatcacc
     1921 gagcaagacg cacaggaaat gattgaccac ctggtcatga aactgcgtat ggttcgcttc
     1981 ctgcgtactc cggaatatga tgaactgttc tccggcgacc cgatttgggc aaccgaatct
     2041 atcggcggta tgggcgttga tggccgtact ctggtcacca aaaacagctt ccgtttcctg
     2101 aacaccctgt acaccatggg gccgtctccg gagccgaaca tcaccgttct gtggtctgaa
     2161 aaactgccgc tgaacttcaa gaagttcgcc gctaaagtct ccatcgacac ctcttctctg
     2221 cagtacgaga acgatgacct gatgcgtccg gacttcaaca acgatgacta cgctatcgca
     2281 tgctgtgtaa gcccgatgat cgttggtaaa caaatgcagt tcttcggcgc gcgtgcaaac
     2341 ctggcgaaaa ccatgctgta cgcaatcaac ggcggcgttg atgaaaaact gaaaatgcag
     2401 gttggtccga aatccgaacc gatcaaaggc gatgttctga acttcgacga agtgatggat
     2461 cgcatggatc acttcatgga ctggctggct aaacagtatg tcaccgcact gaacgttatc
     2521 cactacatgc acgacaagta cagctacgaa gcctctctga tggcgctgca cgaccgtgac
     2581 gttatccgca ccatggcgtg tggtatcgca ggtctgtccg ttgcggctga ctccctgtct
     2641 gccatcaaat atgcgaaagt taaaccgatt cgtgacgaag atggtctggc tatcgacttc
     2701 gaaatcgaag gcgaataccc gcagtttggt aacaacgacg ctcgtgtaga tgacatggcg
     2761 gttgacctgg tagaacgttt catgaagaaa attcagaaac tgaccaccta ccgtggcgct
     2821 atcccgacgc agtctgttct gaccatcact tctaacgttg tgtatggtaa gaaaaccggt
     2881 aacaccccgg atggtcgtcg cgctggcgcg ccgttcggac caggtgctaa cccgatgcac
     2941 ggtcgtgacc agaaaggcgc tgtcgcttct ctgacctccg ttgctaaact gccgtttgct
     3001 tacgcgaaag atggtatttc ttataccttc tctatcgttc cgaacgcact gggtaaagac
     3061 gacgaagttc gtaagactaa cctggcaggt ctgatggatg gttacttcca ccacgaagcg
     3121 tccatcgaag gcggtcagca cctgaacgtc aacgtcatga accgtgaaat gctgctggac
     3181 gcgatggaac atccggaaaa atatccgcag ctgaccatcc gtgtatctgg ttacgcagta
     3241 cgttttaact ccctgacgaa agaacagcag caggacgtta ttactcgtac cttcacgcag
     3301 accatgtaat gggtttgact gaaattacgc ca
//
LOCUS       DAJVBX010000291         3305 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.291, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000291 DAJVBX010000000
VERSION     DAJVBX010000291.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3305
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.291"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            18..2126
                     /gene="foxA"
                     /locus_tag="OPV72_004293"
     CDS             18..2126
                     /gene="foxA"
                     /locus_tag="OPV72_004293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrioxamine B receptor FoxA"
                     /protein_id="HCR9916427.1"
                     /translation="MPLEMFMFATTRMALLIGGAIGGATFPLFAQETTKNDTVIVTSP
                     VQSGATRLATPDIETPQSVSIITRQQFEEQGATSVRQAVSYTPGVYSNQIGASNRFDY
                     IVLRGFSDGSLDNVYLDGLKMMGDTNSHSSLVVDPWFLEDIEVVRGPASVLYGRSSPG
                     GIVSLTSRKPAFDAGGEVKLFAGNNNQRGAAFDVTGPLDDNERVAARLSGMTRYADSQ
                     FTPLKEERYALMPSLTWRITDRTRLDLMAYLHRDPQGGSHSGLPYQGTVVPYNGGKIS
                     NTFFEGEDDYDKYDRRENMVGYNIEHLFDNGWSVRQKLRYLHTKVTLNQVYAAGWLNE
                     TALNRGYSGSGEKMSAIALDNQLDGSVDTGAINHRLLVGIDYQDRSNHTTGYYGAFPP
                     IDAFNPVYGAQPDYITLYSREKHKLRQTGYYLQDQMSWDRWRFTLGGRYDRVSVSNID
                     KLHDSRSDLDKNNVSTRAALLYLFDNGVAPYLSYSTAFTSTSFADENGNVLEPMKGKQ
                     WEAGVKYEPLGGNSQFSAAVYRINQTNIATKEEPTDPYRSIGEIESKGVELEAISHLS
                     DSVRLQAAYTYTDIRYKKSSPQEQGKRAVYAPRNQASAWLSYDVKSGLLEWLTLGSGI
                     RYVNGVTSDRLNTHTLPSYTLVDMVVGYDLSSIGLNGLSAQLNVNNLTDKRYVAACNS
                     LSYCYFGAERSIVGSVSWAF"
     gene            complement(2167..2799)
                     /locus_tag="OPV72_004294"
     CDS             complement(2167..2799)
                     /locus_tag="OPV72_004294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysE family transporter"
                     /protein_id="HCR9916428.1"
                     /translation="MEPFHAVVLTVSLFVLTFFNPGANLFVVVQTSLASGRRAGVITG
                     LGVATGDAFYSGLGLFGLATLITQCEAVFSLIKIVGGAYLLWFAWNSIRHQATPQMST
                     LQTPIAAPWTIFFRRGLMTDLSNPQTVLFFISIFSVTLSAETPTWARLMAWAGIVLSS
                     VIWRIFLSQAFSLPAVRRAYGRIQRIASRVIGAIIGMFALRLLYEGMTHR"
     gene            3031..>3305
                     /locus_tag="OPV72_004295"
     CDS             3031..>3305
                     /locus_tag="OPV72_004295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HCR9916429.1"
                     /translation="MKTGYKVMLGALAFVVTNVYAAEIMKKTDFDKVASEYTKIGTIS
                     TTGEMSPLDAREDLIKKADEKGADVVVLTSGQTENKIHGTADIYKKK"
BASE COUNT          843 a          792 c          906 g          764 t
ORIGIN      
        1 tcttatttac aataaagatg cctttggaga tgttcatgtt tgcgacaacg cgtatggcgc
       61 tattgatagg cggagctatc ggcggcgcga cttttcctct ttttgcccag gaaaccacaa
      121 aaaatgatac cgtcattgtc acctcgcccg ttcagagtgg cgcgaccagg ctggcgacgc
      181 cagatattga aacgccgcag tcggtatcca ttattacccg ccagcagttt gaagagcagg
      241 gcgcaaccag cgtgcgtcag gcggtcagct acaccccagg cgtatacagt aaccagatag
      301 gcgcctctaa ccgctttgat tacatcgtat tgcgtggttt ttcggacggt agtctggata
      361 acgtctatct cgacgggtta aaaatgatgg gcgacaccaa ttcgcacagt tcgttggtgg
      421 ttgacccctg gtttctggaa gatatcgagg tggtacgcgg cccggcgtcc gttctgtatg
      481 gacgttcatc gccaggcggc attgtctcgt tgacgtcgcg aaaaccggcg tttgatgccg
      541 gaggagaagt gaagctgttt gccggcaata acaaccagcg cggggcggct tttgatgtga
      601 ccggcccact ggatgacaat gaacgtgtgg cggcgcgtct tagcggcatg acacgttacg
      661 ccgattcgca gtttacgccc ctgaaagagg aacgttatgc gctgatgccg agcctgacct
      721 ggagaattac cgatcggacg cgtcttgatc ttatggccta tctgcaccgt gatccgcaag
      781 gcggtagcca ctccggactg ccttatcaag gcacggttgt accttataac ggcggaaaaa
      841 tttctaacac tttctttgaa ggtgaagatg actacgacaa atacgatcgc cgtgaaaata
      901 tggtgggtta taacattgag catctgttcg ataacggctg gtcggtacgg caaaaattgc
      961 gttatttgca taccaaagtg acgttgaatc aggtctatgc cgcaggttgg ttgaatgaaa
     1021 cggcgctgaa tcgcggctat tccggctccg gggagaaaat gtcggctatc gcgctggata
     1081 atcagctcga cggcagcgtg gataccgggg cgattaatca tcgtctgctg gtggggatcg
     1141 attatcagga tcgcagtaat catactactg gctattatgg cgcgtttccg ccgattgacg
     1201 ctttcaaccc tgtttatggc gctcagccgg attacattac gttgtatagc cgtgaaaaac
     1261 ataagctgcg gcagaccgga tactatttac aggatcagat gtcatgggat cgctggcgct
     1321 ttacgttggg cggtcgttac gatcgggtca gcgtgtctaa catcgacaaa cttcatgatt
     1381 cacgcagcga tctcgataaa aacaacgtca gcacccgtgc cgcgttgctt tatctgttcg
     1441 acaatggcgt cgccccctat ctcagttatt ctaccgcgtt tacgtcgacc agcttcgccg
     1501 acgaaaacgg caatgtgctg gaaccgatga aaggcaagca gtgggaggcg ggggtaaaat
     1561 acgaaccgct gggggggaac agccagttta gcgccgccgt gtatcgtatt aaccaaacca
     1621 atatcgcgac caaagaagaa cctaccgatc cgtaccgctc gattggtgaa attgagtcta
     1681 aaggggttga actggaggcc attagccatt tgtcggatag cgtccgtttg caggcggcgt
     1741 atacctatac tgatatccgt tataagaaaa gtagcccgca agagcagggg aagcgcgcgg
     1801 tttatgctcc acggaaccag gccagcgcct ggctaagcta cgatgtgaaa agcggtctgt
     1861 tagagtggct gactttgggc tccggcatcc ggtacgtcaa cggcgtgacc agcgatcgcc
     1921 tgaataccca cacgttgccg tcctatacac tggtcgacat ggtggttggg tatgatttat
     1981 ccagcattgg gttaaatggc ttgagcgccc agctcaacgt aaataatctg acggacaaac
     2041 gctatgtcgc tgcctgtaat tcgctctctt attgttattt tggcgccgag cgtagcattg
     2101 taggcagcgt gtcatgggcg ttttgataac gcttatcgtc cggtagcaaa ggctaccggg
     2161 caaacattag cggtgcgtca tgccttcata gagaagtctg agcgcaaaca tcccgataat
     2221 ggcgccgata acacggctgg caatgcgctg tattcgtcca taagcgcggc ggactgcggg
     2281 gagcgaaaag gcctggctga gaaaaatacg ccagataacg gatgacagca caattccggc
     2341 ccaggccatt aaccttgccc atgtgggcgt ttctgcgcta agcgttacgg aaaaaatact
     2401 gataaaaaac agtacggttt gcggattgga taaatcggtc attaatcccc ggcgaaagaa
     2461 aattgtccac ggggcggcaa tcggcgtctg gagcgtgctc atttgcggcg tcgcctggtg
     2521 gcgaatactg ttccaggcga accataataa ataggcgccg ccgacaattt tgataagaga
     2581 aaataccgct tcgcattgcg taatgagcgt cgccagaccg aaaagcccca gcccggaata
     2641 aaaggcgtct cccgtggcga cgcccaggcc ggtgatgact cccgcccggc gtcctgatgc
     2701 gaggctggtt tgcaccacca caaacagatt cgcgccggga ttaaaaaagg ttaacacaaa
     2761 cagactgacg gtaagcacaa cggcatgaaa cggctccata gacaactctt cccatagcct
     2821 caagaaataa cgttcatctt attaatagtc aaaccagatg attgcgagtg agatcacaaa
     2881 gcaggggcgt tttaatccgc gtcgttatgc cgagtgagcg ggggctgact ggatttttcc
     2941 agcaatctac actacttatt taatcagtcc gaacggcctt tttgttctga taaagcgatg
     3001 atggcgtaat aataaaacga gggttttgct atgaaaactg gctacaaggt tatgcttggc
     3061 gcattagcgt ttgtcgtgac aaacgtttat gccgcagaaa tcatgaaaaa aacggacttt
     3121 gataaagtcg cctccgaata cacgaaaatt ggcacgattt ccaccaccgg ggaaatgtcg
     3181 ccgctggacg ccagagaaga tttaatcaaa aaggcggatg aaaaaggggc ggatgtggtg
     3241 gtgctgacgt ccgggcagac agaaaataaa attcatggta cggctgatat ttataaaaag
     3301 aaata
//
LOCUS       DAJVBX010000292         3225 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.292, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000292 DAJVBX010000000
VERSION     DAJVBX010000292.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3225)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3225)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3225
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.292"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            102..3107
                     /locus_tag="OPV72_004296"
     rRNA            102..3107
                     /locus_tag="OPV72_004296"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          857 a          712 c          999 g          657 t
ORIGIN      
        1 tcaagctgaa aattgaaaca cagaacaacg aaagttgttc gtgagtctct caaattttcg
       61 caacacgatg atgaatcgaa agaaacatct tcgggttgtg aggttaagcg actaagcgta
      121 cacggtggat gccctggcag tcagaggcga tgaagggcgt gctaatctgc gataagcgcc
      181 ggtaaggtga tatgaaccgt tataaccggc gatacccgaa tggggaaacc cagtgtgatt
      241 cgtcacacta tcattaactg aatccatagg ttaatgaggc gaaccggggg aactgaaaca
      301 tctaagtacc ccgaggaaaa gaaatcaacc gagattcccc cagtagcggc gagcgaacgg
      361 ggaggagccc agagcctgaa tcagcatgtg tgttagtgga agcgtctgga aaggcgcgcg
      421 atacagggtg acagccccgt acacaaaagc gcatatgctg tgagctcgat gagtagggcg
      481 ggacacgtgg tatcctgtct gaatatgggg ggaccatcct ccaaggctaa atactcctga
      541 ctgaccgata gtgaaccagt accgtgaggg aaaggcgaaa agaaccccgg cgaggggagt
      601 gaaaaagaac ctgaaaccgt gtacgtacaa gcagtgggag ccccaccact aagccagtgg
      661 tgaactccac atacgcatcc tttgctgagg agacggttaa cggagcgaaa gcgacgttca
      721 acctcaaaag aagcagaggg ggcttagtgg tggggtgact gcgtaccttt tgtataatgg
      781 gtcagcgact tatattctgt agcaaggtta actgtatagg ggagccggag ggaaaccgag
      841 tcttaaccgg gcgttaagtt gcagggtata gacccgaaac ccggtgatct agccatgggc
      901 aggttgaagg ttgggtaaca ctaactggag gaccgaaccg actaatgttg aaaaattagc
      961 ggatgacctg tggctggggg tgaaaggcca atcaaaccgg gagatagctg gttctccccg
     1021 aaagctattt aggtagcgcc tcgtgaattc atctccgggg gtagagcact gtttcggcta
     1081 gggggccatc ccggcttacc aacccgatgc aaactgcgaa taccggagaa tgttatcacg
     1141 ggagacacac ggcgggtgct aatgtccgtc gtgaagaggg aaacaaccca gaccgccagc
     1201 taaggtccca aagtcatggt taagtgggaa acgatgtggg aaggcccaga cagccaggat
     1261 gttggcttag aagcagccat catttaaaga aagcgtaata gctcactggt cgagtcggcc
     1321 tgcgcggaag atgtaacggg gctaaaccat gcaccgaagc tgcggcagcg acaccgtgtg
     1381 ttgttgggta ggggagcgtt ctgtaagcct gtgaaggtgt gctgtgaggc atgctggagg
     1441 tatcagaagt gcgaatgctg acataagtaa cgataaagcg ggtgaaaagc ccgctcgccg
     1501 gaagaccaag ggttcctgtc caacgttaat cggggcaggg tgagtcgacc cctaaggcga
     1561 ggccgaaagg cgtagtcgat gggaaacggg ttaatattcc cgtacttggt gttactgcga
     1621 aggggggacg gagaaggcta tgttggccgg gcgacggttg tcccggttta agcgtgtagg
     1681 tatgtgttcc aggtaaatcc ggttcacttt aacactgagg cgtgacgacg aggcactacg
     1741 gtgctgaagc aacaaatgcc ctgcttccag gaaaagcctc taagcatcag gtaacatcaa
     1801 atcgtacccc aaaccgacac aggtggtcag gtagagaata ccaaggcgct tgagagaact
     1861 cgggtgaagg aactaggcaa aatggtgccg taacttcggg agaaggcacg ctgacacgta
     1921 ggtgaagtga tttactcacg gagctgaagt cagccgaaga taccagctgg ctgcaactgt
     1981 ttattaaaaa cacagcactg tgcaaacacg aaagtggacg tatacggtgt gacgcctgcc
     2041 cggtgccgga aggttaattg atggggtcag cgcaagcgaa gctcctgatc gaagccccgg
     2101 taaacggcgg ccgtaactat aacggtccta aggtagcgaa attccttgtc gggtaagttc
     2161 cgacctgcac gaatggcgta atgatggcca ggctgtctcc acccgagact cagtgaaatt
     2221 gaactcgctg tgaagatgca gtgtacccgc ggcaagacgg aaagaccccg tgaaccttta
     2281 ctatagcttg acactgaaca ttgagccttg atgtgtagga taggtgggag gctttgaagt
     2341 gtggacgcca gtctgcatgg agccgacctt gaaataccac cctttaatgt ttgatgttct
     2401 aacgtggacc cgtgatccgg gttgcggaca gtgtctggtg ggtagtttga ctggggcggt
     2461 ctcctcctaa agagtaacgg aggagcacga aggttggcta atcctggtcg gacatcagga
     2521 ggttagtgca atggcataag ccagcttgac tgcgagcgtg acggcgcgag caggtgcgaa
     2581 agcaggtcat agtgatccgg tggttctgaa tggaagggcc atcgctcaac ggataaaagg
     2641 tactccgggg ataacaggct gataccgccc aagagttcat atcgacggcg gtgtttggca
     2701 cctcgatgtc ggctcatcac atcctggggc tgaagtaggt cccaagggta tggctgttcg
     2761 ccatttaaag tggtacgcga gctgggttta gaacgtcgtg agacagttcg gtccctatct
     2821 gccgtgggcg ctggagaact gaggggggct gctcctagta cgagaggacc ggagtggacg
     2881 catcactggt gttcgggttg tcatgccaat ggcactgccc ggtagctaaa tgcggaagag
     2941 ataagtgctg aaagcatcta agcacgaaac ttgccccgag atgagttctc cctgagactt
     3001 taggtctcct gaaggaacgt tgaagacgac gacgttgata ggccgggtgt gtaagcgcag
     3061 cgatgcgttg agctaaccgg tactaatgaa ccgtgaggct taaccttaca acgccgaaga
     3121 tgttttggcg gatgagagac gattttcagc actgattccg gattttcggg aacgaaagat
     3181 aaaagattcg tttccggcaa cagaatttgc ctggcggcac tagcg
//
LOCUS       DAJVBX010000293         3110 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.294, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000293 DAJVBX010000000
VERSION     DAJVBX010000293.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3110)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3110)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3110
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.294"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(195..632)
                     /locus_tag="OPV72_004297"
     CDS             complement(195..632)
                     /locus_tag="OPV72_004297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2778 domain-containing protein"
                     /protein_id="HCR9916430.1"
                     /translation="MAVRLTFDGQKLTWPGIGIFKATTGLPDLQWPDKQCVPDAAIPE
                     GNYKLFIQFQGEAPIRNAADCDLGPSWGWSTIPRGQAAGTCEIYWANWGYNRIRLESA
                     DEKTRKACGGKRGGFYIHDSTKGYSHGCIEVEPVFFRILKQET"
     gene            complement(659..1075)
                     /locus_tag="OPV72_004298"
     CDS             complement(659..1075)
                     /locus_tag="OPV72_004298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2195 family protein"
                     /protein_id="HCR9916431.1"
                     /translation="MKKYAVEVLFMSACAGMFLPVFAWGGTDVNIDNPLAECVDIHPV
                     HRQEMDNLTILKTTVTLKKSTGECGCFSALISYTSLLAQDVEGYGRGSAYSLQEGNIS
                     LAKMQGRYPFSFVLSVDNQSVRDQKLALMIRCTPPL"
     gene            complement(1203..1664)
                     /locus_tag="OPV72_004299"
     CDS             complement(1203..1664)
                     /locus_tag="OPV72_004299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916432.1"
                     /translation="MPRKIMLVFFLFISEFCYAQAVVSEFNLSDINRGGMTKAQAEKL
                     LIIALKYQKYDLSLDGVFVDGDLQDKHGNPPHPGYYDFSLGYDTPTAGAIDYWGLFSV
                     SSQTGDIWEINKCERIIFPQLQKIQQEIMKKTGATFASEVVQRRGLGCTDE"
     gene            complement(1649..2119)
                     /locus_tag="OPV72_004300"
     CDS             complement(1649..2119)
                     /locus_tag="OPV72_004300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000528842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HCR9916433.1"
                     /translation="MGNYDKACNNVGAVRFVQEHMKVCEIIAKELDVPVENILGLAAA
                     ESQYGTGRIARGYNNYFSLQAPASFQSGRVHPKDSNKTWVAIFSSFSVCARSFAVKYG
                     DAVRGKKDALVFSEALVAAGFNSGSHITGGTDNYARITAGIIIMVGRRIACPVK"
     gene            complement(2223..2696)
                     /locus_tag="OPV72_004301"
     CDS             complement(2223..2696)
                     /locus_tag="OPV72_004301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016506348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916434.1"
                     /translation="MFSKIVSLLLFTILSVSSYAQVLVSNIPVFDLAKLNQEGLAETQ
                     AQALLVLSLKNKKYNITLPSVFMDEALKNDQGKPFHSGYYSFGVGYDSPSVGATDIWG
                     LFSVSPKTGDIWEEYSCERISFPALQKIQQEIMKKTGATFASEVVQRRGLGCTDE"
     gene            complement(2681..>3110)
                     /locus_tag="OPV72_004302"
     CDS             complement(2681..>3110)
                     /locus_tag="OPV72_004302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HCR9916435.1"
                     /translation="RFIQKYKNDCEIIANQLEVPVEFILAVAAKESRYGQGRIATEYN
                     NFFSMHGPAPLQLSKVHPQGSHDVWVATYTSFLNCAKSFAIRFGSAVRKINDPKKFAQ
                     ALIESRFNSGKSSNGGHTGYASELVAMIGMVKRRMACSVK"
BASE COUNT          854 a          828 c          528 g          900 t
ORIGIN      
        1 caccgccagt catatacttt atcattggtg ctcgttactt atctggccac cattgtaatc
       61 attgtcaacc acagcacgtt cagacacgat aatttgatcc ggttttaacg gtattattgt
      121 tttgttccac cattcgtttg ctgaccagaa acatacttaa cattaaccgt aaatatcttt
      181 tcaccatttt ctttttacgt ctcctgtttc agaatacgga aaaacaccgg ttccacttca
      241 atacaaccat ggctgtaacc tttggtggaa tcatggatat aaaaaccacc ccgcttgccc
      301 ccacaggctt ttcgggtctt ctcatccgct gattccagcc ggatacggtt atatccccag
      361 ttcgcccagt atatctcaca tgttccggca gcctggcctc gcggaatggt actccagccc
      421 catgatggtc ccagatcaca atccgcagca tttcttatcg gtgcctcccc ctgaaactga
      481 ataaacaatt tataattccc ttccggtatc gccgcatccg gcacacactg tttatctggc
      541 cactgtaaat ccggtaaccc cgtggtcgcc ttaaatatcc cgataccagg ccatgtcagc
      601 ttttgcccgt caaaagtcag tcttactgcc atcatcttct ccctgactat tctgtgtatt
      661 acagcggtgg tgtacaacgt atcattagcg ccagcttctg atcccgtaca gactggttat
      721 ccaccgataa tacaaagctg aaaggataac gtccctgcat cttcgccagt gagatattcc
      781 cctcctgaag ggaatatgca cttccgcgtc cgtaaccctc aacatcctgc gccagtaagc
      841 tggtatagct gattaatgct gagaaacagc cacattcacc ggtacttttt ttcagtgtga
      901 ccgttgtttt cagaatggta aggttatcca tttcctgacg atgaacggga tggatatcca
      961 cacactccgc cagcgggtta tcaatgttta catctgttcc gccccaggca aatacgggca
     1021 ggaacattcc tgcacaggca gacataaaca gaacctctac agcgtacttt ttcacagcat
     1081 ctgacctcta tttttttcat ccaccagccg cagtgcatcc atataccgcc cttcactgtt
     1141 ctgctgccag aaccagcctt gccctggcag gtaacgtatg cccggtagat ccaactatcc
     1201 cactattcat ctgtacagcc cagcccccgg cgctgtacca cttcactggc aaatgtcgcg
     1261 ccagtttttt tcattatttc ttgttgtatt ttttgcaact gcggaaatat aattctctca
     1321 catttattta tttcccatat atcaccagtt tgagaactta ctgaaaacag cccccaataa
     1381 tctattgctc cggcagtcgg tgtatcatag ccaaggctaa aatcataata tcccggatgg
     1441 ggaggatttc cgtgtttatc ctgcaaatca ccgtcaacaa aaacgccatc cagcgataaa
     1501 tcatattttt gatatttaag tgcaataatg agtagttttt ctgcctgtgc tttcgtcatt
     1561 ccaccgcgat ttatatctga caaattaaat tcagatacaa ccgcttgggc ataacagaac
     1621 tcagatataa agagaaaaaa aacaagcatt attttacggg gcatgctatt ctccgcccga
     1681 ccataataat tattccagca gttatcctgg cgtaattatc cgtaccacca gtaatatgag
     1741 atcctgaatt aaacccagca gctaccagag cttcagagaa gaccagagca tcttttttcc
     1801 cccgaacagc gtcaccatac ttgacagcaa aagatcgcgc acaaactgaa aacgaagaaa
     1861 aaatagccac ccaagttttg ttactatcct ttggatgaac ccgacctgac tgaaatgatg
     1921 caggagcctg gagagaaaag taattattat atcccctggc aatacgacct gtaccatatt
     1981 gactttcggc agcagcaaga cccagtatat tctctaccgg tacgtcaagc tcttttgcaa
     2041 ttatctcaca aaccttcatg tgctcctgga caaatcttac cgcacccacg ttattacacg
     2101 ctttatcata attacccatt tcttcattcc ttagcagatg tttttaaaac ctccatgctc
     2161 attatttctc cgccagcctt gcccttgcag gtaacgtatg cccggtagat ccaactaccc
     2221 cgctattcat ctgtacagcc cagccctcgc cgttgcacca cttcactggc aaatgtcgcg
     2281 ccagtttttt tcattatttc ttgttgtatt ttttgtagcg ccggaaatga tattctctca
     2341 catgaatatt cttcccagat atcacctgtt ttcggactga cggaaaataa tccccagata
     2401 tccgtagcac caacagaagg agagtcatag cccacaccaa agctataata tccagaatga
     2461 aatggcttac cctgatcatt ttttaaggcc tcgtccataa aaacgctagg caatgtaata
     2521 ttatattttt tattttttaa tgataaaacc aataatgcct gagcctgtgt ctcggcaagc
     2581 ccttcctgat ttaatttagc caaatcaaac accgggatat ttgatacaag aacctgggca
     2641 taactgctca cggataaaat agtaaacaaa agcaatgaca ctattttact gaacatgcca
     2701 ttctccgctt aaccatacca atcatagcca ccagttcact ggcgtatccg gtatgtcctc
     2761 cattactact tttacctgaa ttaaatcgtg actcaatcaa tgcttgtgca aattttttag
     2821 gatcgtttat ctttctgact gcactaccaa acctgatggc gaatgatttc gcgcaattta
     2881 aaaaagacgt ataggtggca acccacacgt cgtgacttcc ctgaggatga actttactca
     2941 actgcaatgg tgccggacca tgcattgaaa aaaaattatt atattcagtt gcaatccttc
     3001 cctgcccata acgactttcc tttgctgcaa ccgccagtat aaactccact ggcacttcaa
     3061 gttgattagc gattatctca caatcattct tatatttttg aataaacctt
//
LOCUS       DAJVBX010000294         3109 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.295, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000294 DAJVBX010000000
VERSION     DAJVBX010000294.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3109
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.295"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..591
                     /gene="rfbF"
                     /locus_tag="OPV72_004303"
     CDS             <1..591
                     /gene="rfbF"
                     /locus_tag="OPV72_004303"
                     /EC_number="2.7.7.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate cytidylyltransferase"
                     /protein_id="HCR9916436.1"
                     /translation="EYFANYFLHMSDVTFHMAENRMEVHHKRVEPWNVTLVDTGDSSM
                     TGGRLKRVAEYVKDDEAFLFTYGDGVADLDIKATIDFHKAHGKKATLTATFPPGRFGA
                     LDIQAGQVRSFQEKPKGDGAMINGGFFVLNPSVIDLIDNDATTWEQEPLMTLAQQGEL
                     MAFEHPGFWQPMDTLRDKVYLEGLWEKGKAPWKTWE"
     gene            596..1675
                     /gene="rfbG"
                     /locus_tag="OPV72_004304"
     CDS             596..1675
                     /gene="rfbG"
                     /locus_tag="OPV72_004304"
                     /EC_number="4.2.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glucose 4,6-dehydratase"
                     /protein_id="HCR9916437.1"
                     /translation="MIDKNFWQGKRVFVTGHTGFKGSWLSLWLTEMGAIVKGYALDAP
                     TVPSLFEIVRLNDLMESHIGDIRDFEKLRSSIAEFKPEIVFHMAAQPLVRLSYEQPIE
                     TYSTNVMGTVHLLEAVKQVGNIKAVVNITSDKCYDNREWVWGYRENEPMGGYDPYSNS
                     KGCAELVASAFRNSFFNPANYEQHGVGLASVRAGNVIGGGDWAKDRLIPDILRSFENN
                     QQVIIRNPYSIRPWQHVLEPLSGYIVVAQRLYTEGAKFSEGWNFGPRDEDAKTVEFIV
                     DKMVTLWGDDASWLLDGENHPHEAHYLKLDCSKANMQLGWHPRWGLTETLSRIVKWHK
                     AWIRGEDMLICSKREISDYMSATTR"
     gene            1702..3015
                     /gene="rfbH"
                     /locus_tag="OPV72_004305"
     CDS             1702..3015
                     /gene="rfbH"
                     /locus_tag="OPV72_004305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein RfbH"
                     /protein_id="HCR9916438.1"
                     /translation="MTANNLREQISQLVAQYANEALSPKPFVAGASVVPPSGKVIGAK
                     ELQLMVEASLDGWLTTGRFNDAFEKKLGEFIGVPHVLTTTSGSSANLLALTALTSPKL
                     GERALKPGDEVITVAAGFPTTVNPAIQNGLIPVFVDVDIPTYNIDASLIEAAVTEKSK
                     AIMIAHTLGNAFNLSEVRRIADKYNLWLIEDCCDALGTTYEGRMVGTFGDIGTVSFYP
                     AHHITMGEGGAVFTKSGELKKIIESFRDWGRDCYCAPGCDNTCGKRFGQQLGSLPQGY
                     DHKYTYSHLGYNLKITDMQAACGLAQLERVEEFVEQRKANFSYLKQGLQSCTEFLELP
                     EATEKSDPSWFGFPITLKETSGVNRVELVKFLDEAKIGTRLLFAGNLIRQPYFANVKY
                     RVVGELTNTDRIMNQTFWIGIYPGLTTEHLDYVVSKFEEFFGLNF"
BASE COUNT          845 a          604 c          768 g          892 t
ORIGIN      
        1 gaatattttg cgaactactt ccttcacatg tcagatgtaa cattccatat ggctgaaaac
       61 cgtatggaag ttcaccataa acgtgttgaa ccatggaatg tcacattggt tgatacgggt
      121 gattcttcaa tgactggtgg tcgtctgaaa cgtgttgctg aatacgtaaa agatgacgag
      181 gctttcctgt ttacttatgg tgatggcgtt gccgaccttg atatcaaagc gactatcgat
      241 ttccataagg ctcacggtaa gaaagcgacc ttaacagcta cttttccacc aggacgcttt
      301 ggcgcattag atatccaagc tggtcaggtc cggtcattcc aggaaaagcc gaaaggcgat
      361 ggggcaatga tcaatggtgg tttctttgtg ttgaatccat cggttatcga tctcatcgat
      421 aacgatgcaa caacctggga acaagagcca ttaatgacat tggcacaaca gggggagtta
      481 atggcttttg aacacccagg tttctggcag ccgatggata ccctacgtga taaagtttac
      541 ctcgaagggc tgtgggaaaa aggtaaagct ccgtggaaaa cctgggagta agtagatgat
      601 tgataaaaat ttttggcaag gtaaacgtgt attcgttacc ggccatactg gctttaaagg
      661 aagctggctt tcgctatggc tgactgaaat gggtgcaatt gtaaaaggct atgcacttga
      721 tgcgccaact gttccaagtt tatttgagat agtgcgtctt aatgatctta tggaatctca
      781 tattggcgac attcgtgatt ttgaaaagct gcgcagttct attgcagaat ttaagccaga
      841 aattgttttc catatggcag cccagccttt agtgcgccta tcttatgaac agccaatcga
      901 aacatactca acaaatgtta tgggtactgt ccatctgctt gaagcagtta agcaagtagg
      961 taacataaag gcagtcgtaa atatcaccag tgataagtgc tacgacaatc gtgagtgggt
     1021 gtggggctat cgtgagaacg aacccatggg agggtacgat ccatactcta atagtaaagg
     1081 ttgtgcagaa ttagtcgcgt ctgcattccg gaactcattc ttcaatcctg caaattatga
     1141 gcaacatggc gttggtttgg cgtctgtgag ggctggtaat gtcataggtg gaggcgattg
     1201 ggctaaagac cgtttaattc ccgatattct gcgctcattt gaaaataacc agcaggttat
     1261 tattcgaaac ccatattcta tccgtccctg gcagcatgta ctggagcctc tttctggtta
     1321 cattgtggtg gcgcaacgct tgtatacaga aggtgctaag ttttctgaag gatggaattt
     1381 cggcccgcgt gatgaagatg cgaagacggt cgaatttatt gttgacaaga tggttacgct
     1441 ttggggtgat gatgcaagct ggttactgga tggtgagaat catcctcatg aggcacatta
     1501 cctgaaactg gattgctcta aagcaaatat gcaattagga tggcatccgc gttggggatt
     1561 gactgaaaca cttagtcgca tcgtaaaatg gcataaagca tggattcgcg gcgaagatat
     1621 gttgatttgt tcaaagcgtg aaatcagcga ctatatgtct gcaactactc gttaagaaaa
     1681 taagtttaag gaatcaaagt aatgacagca aataacctgc gtgagcaaat ctctcagctt
     1741 gtcgctcagt atgcgaatga ggcattgagc ccgaaacctt ttgttgcagg tgcaagcgtt
     1801 gtacctcctt ccgggaaggt tattggtgcc aaagagttac aattgatggt tgaggcgtct
     1861 cttgatggat ggctaactac tggtcgtttc aatgatgcct ttgagaaaaa acttggggaa
     1921 tttattggag ttcctcatgt tttaacgact acatctggct cttcggcaaa cttgctggca
     1981 ctgactgcgc tgacttcccc aaaattaggc gagcgtgctc tcaaacctgg tgatgaggtt
     2041 attactgtcg ctgctggctt cccgactaca gttaacccgg cgatccagaa tggtttaata
     2101 ccggtattcg tggatgttga tatcccgaca tataatatcg atgcctctct cattgaagct
     2161 gcagttactg agaaatcaaa agcgataatg atcgctcata cactcggtaa tgcatttaac
     2221 ctgagtgaag ttcgtcggat tgccgataaa tataacttat ggttgattga agactgctgt
     2281 gatgcccttg ggacgactta tgaaggccgg atggtaggta cctttggtga catcggaacc
     2341 gttagttttt atccggctca ccatatcaca atgggtgaag gcggtgctgt attcaccaag
     2401 tcaggtgaac tgaagaaaat tattgagtcg ttccgtgact ggggccggga ttgttattgt
     2461 gcgccaggat gcgataacac ctgcggtaaa cgttttggtc agcaattggg gtcacttcct
     2521 caaggctatg atcacaaata tacttattcc cacctcggat ataatctcaa aatcacggac
     2581 atgcaggcag catgtggtct ggctcagtta gaacgcgtgg aagagtttgt agagcagcgt
     2641 aaagctaatt tttcctattt gaaacaaggt ttgcaatctt gcactgaatt cctcgaatta
     2701 ccagaagcaa cagagaaatc agatccatcc tggtttggct tccctatcac cctgaaagaa
     2761 actagcggtg ttaaccgtgt cgaactggtg aaattccttg atgaagcaaa aatcggtaca
     2821 cgtttactgt ttgctggaaa tctgattcgc caaccgtatt ttgctaatgt gaaatatcgt
     2881 gtagtgggtg agttgacaaa taccgaccgt ataatgaatc aaacgttctg gattggtatt
     2941 tatccaggct tgactacaga gcatttagat tatgtagtta gcaagtttga agagttcttt
     3001 ggtttgaatt tctaattttt gagggggggg gattcccctc tatgatttca tgaaaattct
     3061 aataatggga gcgtttgggt tccttggatc acgacttaca tcctacttc
//
LOCUS       DAJVBX010000295         3092 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.296, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000295 DAJVBX010000000
VERSION     DAJVBX010000295.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3092)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3092)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3092
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.296"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            174..1139
                     /locus_tag="OPV72_004306"
     CDS             174..1139
                     /locus_tag="OPV72_004306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012548938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HCR9916439.1"
                     /translation="MKKSTTSTPHDAVFKTFLRHPETARDFMEIHLPVSLRQLCDLRT
                     LKLEPGSFIEKNLRAYYSDVLWSLKTREGDGYIYVVIEHQSTPDAHMAFRLMRYAMAA
                     IQQHLDAGHKHLPLVVPMLFYHGVDSPYPFSLCWLDEFANPEVARRLYAAAFPLVDIT
                     VVSDDDIMQHRRIALLELIQKHIRQRDLLGLVERIASLLVTGCANDRQLKALFNYLMI
                     QHGHTPRFTTFIRDVVGHVPHTKERLMTLIERIRAADRRKGERQGRQLGLEEGLAEGL
                     EKGLEKGQHVAALRIARQMLADGLDRETVQRFTGLTAEELQDVSH"
     gene            1320..2691
                     /locus_tag="OPV72_004307"
                     /pseudo
     CDS             1320..2691
                     /locus_tag="OPV72_004307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463378.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent succinate-semialdehyde
                     dehydrogenase"
     gene            complement(2787..2930)
                     /locus_tag="OPV72_004308"
     CDS             complement(2787..2930)
                     /locus_tag="OPV72_004308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916440.1"
                     /translation="MVVWGGSRKIPYQPPHRTENAGIMNVCTNNTGIKSTVSATWINK
                     EGD"
     gene            2897..3061
                     /locus_tag="OPV72_004309"
     CDS             2897..3061
                     /locus_tag="OPV72_004309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1127 domain-containing protein"
                     /protein_id="HCR9916441.1"
                     /translation="MEFYENRPRQPFIGYVQLRRALKRWWLRKRACQALRRMSDEQLR
                     DIGLERKDVE"
BASE COUNT          739 a          751 c          911 g          691 t
ORIGIN      
        1 aaaggcaggg cgcgcaggct ggtattttgc gtgttcagtt ccgaaaatgc atgtgcatta
       61 cagataacag gatttatctt tcgtcgcgcc tcgcaatgct gaaaaggtac ggatgagaaa
      121 ggaattttca ggaggtagag tcgcagcatc ctggttttgg gtgacggagc gccatgaaaa
      181 aatcgacgac ctcaacaccg catgatgcgg tgtttaaaac ctttttgcgc cacccggaaa
      241 ccgcccgcga ttttatggag attcatctgc cggtgtcgtt acgccagctt tgcgatctgc
      301 ggacgctaaa gctggagccc ggcagcttta ttgaaaaaaa tctgcgagcc tattattccg
      361 atgtgctttg gtcgctgaaa acgcgcgagg gcgacggtta tatctatgtc gtgattgaac
      421 atcagagcac gccggatgcg catatggcgt ttcggctgat gcggtatgcg atggcggcaa
      481 tacaacagca tctggatgcg gggcataagc atcttccgct ggtggtgccg atgctgtttt
      541 atcacggtgt tgatagcccg tatccttttt cgctgtgctg gctggatgag tttgcgaacc
      601 cggaagtggc aagaagactc tatgccgctg cctttccgct ggtcgacatt acggtggtat
      661 cggatgatga cattatgcag caccgccgca ttgcgctgct ggagctcatc caaaaacata
      721 tccgccagcg cgacctgctg ggactggttg aacggattgc ttcgctgtta gttactggtt
      781 gcgctaatga caggcagctt aaagcgctgt ttaattatct tatgattcag cacggacata
      841 cgcctcgttt caccacgttt attcgtgatg tggtagggca tgtcccgcac actaaggaga
      901 gactgatgac gctgatagag aggatccgcg cagcggatcg cagaaaaggg gaacggcaag
      961 gaagacagct cggtctggag gaaggattag cagaaggatt agaaaaaggg ctggaaaaag
     1021 gtcagcatgt tgccgcattg cgtatcgcca gacagatgct ggcggacgga cttgaccgcg
     1081 agactgtcca gcggttcacc ggccttacgg ctgaagagct tcaggatgtt agtcactaac
     1141 gcggctccag tctgaatgtt gcaggcccgg tgcccaccgg gcaacgcgct ctataattat
     1201 cgttgataac cgtacgaata taccgaactt taccgatagc gccagccatc tctactaccc
     1261 ttattgttct gagcggcatt tccggctgcc ttaatgacga taacaaggag acatgtgata
     1321 tggcttacca gacagtgaat cctgccaata atcagctcat taaagagtat cccccgcaca
     1381 cggacgcgga tattgaagcc gcgctgcaaa aagctgacgc gctctatcac tccgactggt
     1441 ccaggggaga gattgaccaa cgtttgccgg tactgcataa gctggctgac ttgatcgaca
     1501 gccgtgttga agaactggca aaaatcgcca gccaggagat gggcaagctc atcgagcaaa
     1561 gccgtggcga agtcaaactc tgtgcgcaga tcgctcgcta ttatgcggat aacgcgaagc
     1621 agtttcttgt cccggtgcct tataaaaccg agtttggcga cgcgtgggta gaacatcatc
     1681 cgattggcgt catcatggct gttgagccgt ggaacttccc gtactatcag ttgatgcgtg
     1741 tgctggcgcc gaacctggcc gctggtaacc cggtgctggc gaaacatgcc agcatcgtac
     1801 cgcactgcgc cgagacattt gcccatctgg tgcgtgaagc cggcgcgccg gatggcgcat
     1861 ggaccaacct gtttatttcc tccgatcagg tggcgaatat catcgccgac ccgcgcgtgc
     1921 agggcgcggc gctgaccgga tctgaaaaag cggggagcgc cgtggcggca caggcggcga
     1981 agcacattaa aaaatcgacg ctggaactgg gcgggaacga tgtgttcgtc gtgctggaca
     2041 atgccgatct tgagaaagcg gtgaaaattg gcgtgcaggc acggctcact aatgcggggc
     2101 aggtatgtac ggcggcgaag cgctttatcc tgcatgagaa aatcgccgat caattcctca
     2161 gccagttcac cgaggcgttc aggaaggtga aggtggggga tcagatggac gcttctaccg
     2221 aactggggcc gctgtcgtcg aaagatgcgc tggaaacatt gaccagacag gtcgaggaag
     2281 cggtgaaaaa tggcgcgacg ctgcacgttg gcggcaagcc gctggaaagc aaaggcaact
     2341 tctttgagcc gaccattctg acccacatta cgcgtgacaa cccggcgtac tttgaagagt
     2401 tcttcggccc ggtggcgcag atgtatgtgg tgaaagacga tgatgaggcg gtaaaactcg
     2461 ccaacgattc ccactacggc cttggcggcg cggtgtttag tcaggatatt gagcgcgcta
     2521 aacgcatgtg cctcccggat tgaaaccggg atggtttata tcaactggct gaccgacacc
     2581 gcagcggagc tgccgttcgg cggcgttaag cgttcgggct tcggacgcga gctatcggat
     2641 ctggggatta aggagtttgt gaaccagaag ctggtagtgg tacgccgcta atccctgttg
     2701 cccctctgaa aacgggaggg gcctggcttt tttgcagcga aggacgcaga tcttaaatca
     2761 gaacgaaata aacgaacaaa acaccctcaa tcgccctcct tatttatcca cgttgcacta
     2821 accgtgcttt ttatcccggt attgtttgta cagacattca tgatgcccgc attttctgtt
     2881 ctatgcggag gctggtatgg aattttacga gaaccgcccc agacaaccat tcattggcta
     2941 tgtgcagctc agacgggcgc taaaaaggtg gtggctgcgt aagcgggcct gtcaggcgct
     3001 gcgacgaatg agtgacgagc agttaaggga tattgggttg gaaaggaagg atgtggaata
     3061 gtgaatctat tcaagggcaa tagtaagtaa ag
//
LOCUS       DAJVBX010000296         3092 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.297, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000296 DAJVBX010000000
VERSION     DAJVBX010000296.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3092)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3092)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3092
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.297"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..662)
                     /locus_tag="OPV72_004310"
     CDS             complement(<1..662)
                     /locus_tag="OPV72_004310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HCR9916442.1"
                     /translation="MSQNNYLIDKRVILDCERMTLSCAGELITISESERSLLITFYEG
                     LFKKDDLINYVWGRKGVVVSDASYYKLINQLRGSFDKIGLKGESVVTRPRVGVLLSVS
                     IEPLSDEAQDMPLPAVAETELSTVEVRHDDTIIPPIPGAVNRKDWLYFCLAALLMFFM
                     IYKVKGENIDYFTLNGSYDGYTFYSVGHDKTHLADIIEAYSEMSNEIHKQNGKIIYYI
                     RVP"
     gene            complement(762..2336)
                     /locus_tag="OPV72_004311"
     CDS             complement(762..2336)
                     /locus_tag="OPV72_004311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic diguanylate phosphodiesterase"
                     /protein_id="HCR9916443.1"
                     /translation="MKVRKLFLMLFIAVPLIVMILVGLLAGIFQLKRDIAVSANTLLR
                     FSADISAASWQVAGKAARLAESSCTDTLKELSRTRAFTPYVRDIGFLENGDITCSFVT
                     GTERYHFSRLAGLSLPASYPERWLRSIGSMAEGPDRLVVVYVKKVAADKAAFVIVDSQ
                     YVQELMEILAAERASAFSLIFGAGEAITSAATLRGKAFLTQRFTSTDHTIQLMVRTPF
                     STLSAYWLQNLFIFIPLSLCLSVGMILFYRRWYLKRLSLAREISRGITHNEFTVHYQP
                     VFNVKHGSCGGVEALMRWPQPDGRFITPDIFITAAENEGMIIPLSRHLFELIAHDVIN
                     WTVPDDFYISVNISPAHLMDDGFIQDIEALRTRLGTITLMLELTERSLIVEPSQVAEK
                     LSTLREKGVLIAIDDFGTGYCSLSYLQQLPVDSLKIDRTFIDTIDTSSDDVPVLDTII
                     TLSQRLGLNVVAEGVSTQHQLRYILSHGVGFVQGFLYARPMGTNDFMSWLGKSAQRQN
                     GLLKGESGSASDLVAE"
     gene            complement(2848..3092)
                     /locus_tag="OPV72_004312"
                     /pseudo
     CDS             complement(2848..3092)
                     /locus_tag="OPV72_004312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459337.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          919 a          736 c          628 g          809 t
ORIGIN      
        1 ggaacgcgaa tgtaataaat gatttttccg ttttgtttat gtatttcatt actcatctca
       61 gagtacgctt caatgatatc cgccagatgg gttttatcat gcccgacact ataaaaagtg
      121 tatccatcat acgaaccatt gagggtaaaa taatcaatat tttcaccctt aactttataa
      181 atcataaaaa acatcagaag cgcggccagg caaaagtaga gccaatcttt tctattcaca
      241 gcgcccggta ttgggggaat aatagtatca tcgtgccgca cttcaaccgt cgataattct
      301 gtttcagcaa cagcaggcaa cggcatatct tgcgcctcat cactcaacgg ttcaatggaa
      361 actgagagta aaacacccac gcgagggcga gtcacaacag actccccctt aagaccaatt
      421 ttatcaaatg atcctcgtag ctggttaatc agtttataat aactggcatc agagaccaca
      481 acacctttgc gcccccagac atagttaatt aaatcatctt ttttaaaaag gccttcataa
      541 aaagtgataa gcaaactgcg ttccgattca gatatcgtta tcaactctcc ggcgcaggaa
      601 agcgtcattc gttcacaatc aagaataacc cttttgtcaa tcagataatt gttctgactc
      661 ataaaaatat ccgccccagt gctatcacgt ttcttcacgg cataaacata ttactaggat
      721 atatcgtgct attgaatttt tttccgtagc gagttcctgc attattcagc caccagatcg
      781 ctcgcggatc cgctttcccc cttgagcaaa ccattttgcc gctgggctga cttgccaagc
      841 caactcataa agtcattagt ccccatcggc ctggcataaa gaaatccctg aacgaatcct
      901 accccgtggc ttaagatgta acgcaattgg tgctgggtac tgaccccttc ggcaaccaca
      961 ttgagtccca gtcgctgact cagcgtaatg atagtatcca ggacaggaac atcatcgctg
     1021 ctggtatcaa tggtatcgat aaacgttctg tctattttaa gagagtctac aggtaattgc
     1081 tggagatagg agagggagca atagccggtc ccaaaatcat caatcgctat taacacgcct
     1141 ttttcacgga gcgttgaaag tttttctgcg acctgtgaag gttctacaat caggctacgt
     1201 tcggtgagct ccaacataag cgttatcgtt cccaaacgag tcctgagcgc ctctatatct
     1261 tgtataaaac cgtcatccat aagatgcgca ggcgatatat ttacgctgat atagaaatca
     1321 tccggtacag tccagtttat cacgtcatga gcaatcagtt cgaacagatg acgagagagt
     1381 ggaataatca tgccttcatt ttctgcggcg gtaataaaaa tatcgggagt tataaaacgg
     1441 ccatccggtt gcggccagcg cattagcgcc tccacgccgc cgcaactacc gtgtttaaca
     1501 ttaaaaacag gttgataatg taccgtaaat tcattgtgcg ttattcccct ggaaatctcc
     1561 cgggccagag ataagcgttt taaataccag cgcctgtaga acaatatcat ccctacagaa
     1621 agacataatg acagcggaat aaaaataaaa aggttttgta accagtatgc cgataacgtt
     1681 gagaaagggg ttcgcaccat cagctggata gtgtgatcgg ttgaggtgaa ccgctgcgtt
     1741 aaaaacgcct taccgcgcaa cgtcgcagcg ctggtaatcg cctctcctgc gccgaatatc
     1801 aggctaaagg ctgatgctct ttctgcagcc aatatctcca tgagctcctg gacatactgc
     1861 gaatccacaa tgacgaaagc cgctttatcc gctgctactt ttttcacata caccacaaca
     1921 aggcgatcgg gtccttcggc catactaccg atagatcgca accaccgttc cggataagaa
     1981 gcaggtaaag aaagccctgc cagccgggaa aaatgatagc gttcggttcc tgtgacaaag
     2041 gagcaagtga tatcaccatt ttccagaaac ccaatgtcac ggacataagg agtgaaggcc
     2101 cgcgttctgg acagttcttt cagcgtgtca gtacaggaac tctcagccag tctggcggct
     2161 tttccggcga cttgccagga ggcggcggat atatccgcgc taaaccgcag cagcgtattg
     2221 gcgctgacgg cgatatctcg ttttagctgg aagatacccg cgagtaaccc caccaatatc
     2281 attacgatca gtggaacggc aataaacaac atcagaaata gctttcttac tttcaaatca
     2341 ttgccctctt accggccttc cttttgccac tgtacgcttt tataggataa ctaaagtaac
     2401 attaatagag aaaagaaata ttgagagata ggttatacgt tcttaatgat agcaagatgg
     2461 cactccctgt gccgaaaaca gacaagagaa tatcaatacc caacaggtgc aggatactat
     2521 cgttaaaatg agcgataaca gatatctaaa taaagacgca ttcaatatgt tagcctgatg
     2581 ccaggttcac tgcctgatga gacataacca tcacggaacg aattcccatc aatacaggga
     2641 ttattggtta caactcaacg ttactactgg tggtacacac attatacaaa tgccgattaa
     2701 gcgaaaacat gtaggtgttt ttcccaattt tgacaatttt tagctcatta atcgtaccgg
     2761 gttgtaacaa cctcaaccag gaaaataaat cgccagcagt atcagactca aaggtcttaa
     2821 ctgaattgac tttaaaagta aatgttttca tacccgttct gcgcagtttg ctgatgcaga
     2881 tgtcacgaaa aaaaaagccg tttctctttc gtatcggtag taacatcgta gtgtagggta
     2941 atcctgccgg atttaagatc cagcacaagt ccaccatcca tgtacaattt tcgtggttca
     3001 atatacgctt ctgattttgt cgtgcatata agattattgg ttctataaga gtcacgattt
     3061 acccactcaa gcgctattac cgatccgatt gc
//
LOCUS       DAJVBX010000297         3011 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.298, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000297 DAJVBX010000000
VERSION     DAJVBX010000297.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3011)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3011)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3011
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.298"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            42..2705
                     /gene="tssH"
                     /locus_tag="OPV72_004313"
     CDS             42..2705
                     /gene="tssH"
                     /locus_tag="OPV72_004313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system ATPase TssH"
                     /protein_id="HCR9916444.1"
                     /translation="METPVSRSALYGKLAGPLFRSLESATAFCKLRSNPWGELTHWLH
                     QLTQQPDNDILHVLRHYQIPLSDVEKALLRQLDMLPAGASAISDFSHHIDLSVEKAWM
                     LASVRYGDNKIRSGWLLLALLTTPELRRVLSSICAPLATLPVDELTEILPSLIETSPE
                     AQERPYDGSGLASAIPGESSQAIPNGVQDGKSALAKYCQDMTAQARDGKIDPVTGREH
                     EIRTMTDILLRRRQNNPLLTGEAGVGKTAVVEGFALAIAQGEVPPALREVRLLALDVG
                     ALLAGASMKGEFESRLKGLLEEAGRSPQPVILFVDEVHTLVGAGGASGTGDAANLLKP
                     ALACGTLRTIGATTWSEYKRHIEKDPALTRRFQVLQIAEPEEIPAMEMVRGLVDTLEK
                     HHNVLILDEAVRAAVQLSHRYIPARQLPDKAISLLDTAAVRVALTLHTPPASVQFLRQ
                     QLKAAEMERSLLQKQEKMGIQSDERCDALTARIFSLNDELTASESRWQRELELVHTLQ
                     ELRVAESDADDKTTLQQAETALREWQGDAPVVFPEVSAAIVAAIVADWTGIPAGRMVK
                     DEASQVLELPARLAQRVTGQDGALAQIGERIQTARAGLGDPRKPVGVFMLAGPSGVGK
                     TETALALAEAIYGGEQNLVTINMSEFQEAHTVSTLKGAPPGYVGYGEGGVLTEAVRRH
                     PWSVVLLDEIEKAHHDVHELFYQVFDKGGMEDGEGTHVDFKNTTLLLTTNVGSDLISQ
                     MCEDPALMPDATGLKEALMPELRKHFPAAFLGRVTVIPYLPLDETSRGVIARLHLDRL
                     VARMGEQHGVTLTYSEELVAHIVACCPMHETGARLLIGYIEQHILPQLSRYWLQAMTE
                     KAAIRQIDIGVNGDEQIVFETTSQEGICQKS"
     gene            2791..>3011
                     /locus_tag="OPV72_004314"
     CDS             2791..>3011
                     /locus_tag="OPV72_004314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916445.1"
                     /translation="MTLRDPALLTPLLMMFAFSVHGEPPLPQDVQHFLSNAEMCQHLA
                     GEWDSSLPEEDKKDIKKGINTWCPPAKKAL"
BASE COUNT          667 a          793 c          935 g          616 t
ORIGIN      
        1 tgcattattt ttatgaattt ttatgtcaca aggcataaca aatggaaact cctgtttcac
       61 gcagtgcgtt atatggaaaa ctggccggcc cactattccg gtcgctggaa tcggcaacgg
      121 cattttgcaa actacgctct aatccctggg gtgagctgac tcactggctg caccagttaa
      181 cacagcagcc cgataacgat attctccacg ttcttcggca ttaccagatc cctctttctg
      241 atgtggagaa agcgttactc cggcaactgg atatgctgcc cgccggggcc agcgccatta
      301 gtgatttttc tcaccatatc gatctcagcg ttgaaaaggc ctggatgctg gcgagcgtcc
      361 gttacggcga taacaaaatt cgcagcggct ggttgctgct ggccttgttg accacgccag
      421 aactgcgtcg ggtactgagc agtatctgcg cgccgctggc cacgcttccg gttgatgaac
      481 tgacggaaat actgccctcg ttgatcgaaa catcgccgga agcgcaggag cgcccttacg
      541 acggctccgg tctggcatca gccattcccg gtgaaagcag ccaggcgatt cccaacggcg
      601 tgcaggacgg taaatccgcg ctggcaaaat actgtcagga catgacggca caggcgcgcg
      661 acggcaaaat cgacccggtg acggggcgtg agcatgaaat ccgcaccatg acggatattc
      721 tgctgcgccg tcgccagaat aatcccctac tgactggtga ggcgggcgtc ggaaagacgg
      781 cggtcgtcga aggttttgcc ctcgcgattg cgcaggggga agtgccgccc gcgctgcggg
      841 aagtacggct gctggcgctg gacgttggcg ctctgttggc cggagccagc atgaaaggcg
      901 agtttgaatc gcgtctgaaa gggttactgg aagaggccgg gcgctcgccg cagccggtta
      961 ttctgtttgt cgatgaagtt cacactctgg tgggcgcggg cggcgcatcc ggcacgggcg
     1021 atgccgctaa cctgctgaaa ccggcgctgg cgtgcggcac cctgcggact atcggcgcca
     1081 ccacctggag cgaatacaag cgccatattg agaaagatcc ggcgctgacc cgtcgttttc
     1141 aggtgttgca gattgccgag ccggaagaga tccccgcaat ggaaatggtg cgtggtctgg
     1201 tggatacgct ggaaaaacac cataacgtac tgattctgga tgaggcggta cgtgcggcgg
     1261 tacagctttc tcaccgctac attcccgccc ggcagttgcc ggataaggcc atcagcctac
     1321 tggataccgc cgcggtccgc gtggcgctga cgctgcacac gccgcctgcc agcgtacagt
     1381 tcctgcgtca gcagctaaaa gcggcggaaa tggaacggtc gctgttgcag aagcaggaaa
     1441 aaatggggat tcagtcagat gagcggtgcg atgcgctgac ggcgcgaatt ttctcgctca
     1501 acgatgaact gactgcatcc gaatcccgct ggcagcggga gctggaactg gtacatacgt
     1561 tgcaggaact gcgtgtcgca gagtctgatg ctgatgacaa aaccacgctg caacaggccg
     1621 aaacagcgct aagggagtgg cagggcgacg cgccggtggt gttcccggaa gtcagcgcgg
     1681 cgattgtcgc ggcgattgtc gccgactgga ccggtattcc tgccgggcgc atggtgaaag
     1741 atgaggccag ccaggtgctg gaactgcctg cccgactggc gcaacgcgtt accgggcaag
     1801 acggcgcgct ggcgcagatt ggtgaacgta ttcagaccgc cagggcggga ctgggcgatc
     1861 cacgcaaacc ggtgggcgtg tttatgctgg ccgggccgtc cggtgtcggt aaaaccgaaa
     1921 ccgcgctggc gctggcggag gctatctacg gcggtgagca gaacctggta accatcaata
     1981 tgagcgagtt ccaggaggct cacaccgttt ccacactgaa aggcgcgccg cccggctatg
     2041 tgggctatgg cgagggtggt gtgctgacgg aagcggtgcg tcgtcacccc tggagcgtag
     2101 tgctgctcga cgagatcgaa aaagcgcacc atgacgtcca tgaactcttc tatcaggtgt
     2161 ttgacaaggg cgggatggag gacggtgagg gaacacatgt cgatttcaaa aacaccacgc
     2221 tactactcac caccaatgta ggttccgacc tcatcagcca gatgtgtgaa gatccggcct
     2281 taatgcccga tgctacgggg cttaaagagg cgctaatgcc ggaattgcgc aagcatttcc
     2341 cggcggcatt tctgggccgc gtgacggtga tcccttacct gccgctggat gaaacgtcgc
     2401 gtggcgtgat tgcccgtctg catcttgacc ggctggtggc gcggatgggt gaacagcacg
     2461 gggtgacgct gacgtatagt gaggaactgg tcgcacatat tgtggcgtgc tgtccaatgc
     2521 atgaaacggg cgcgcggttg ctgattggct acatcgaaca gcacatcctg ccacaactgt
     2581 cgcgctactg gttgcaggcc atgacggaaa aagccgctat caggcagatt gatatcggcg
     2641 ttaatggtga tgagcagatt gtttttgaga caacctcgca ggagggaata tgccaaaaga
     2701 gttaagtggt gcgcagtggg tttatggcgt gactaagttt gtcggcggaa atacagataa
     2761 accccactgg tcaattgatg ggcattaaat atgacattac gtgacccggc gttattgact
     2821 cctttgctaa tgatgttcgc tttcagtgtt catggcgaac cgcctttacc acaggatgtg
     2881 cagcattttc tgagcaatgc agagatgtgc cagcatctgg ccggcgaatg ggacagttct
     2941 ttaccggaag aggataaaaa agacataaaa aagggcatta atacctggtg ccctccggcg
     3001 aaaaaagcac t
//
LOCUS       DAJVBX010000298         2999 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.299, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000298 DAJVBX010000000
VERSION     DAJVBX010000298.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2999
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.299"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(67..555)
                     /locus_tag="OPV72_004315"
     CDS             complement(67..555)
                     /locus_tag="OPV72_004315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HCR9916446.1"
                     /translation="MSENKNVQDTHISEQMKALHGALIRVVSALNRPRNDEKLIAEAG
                     IQLDRALFSILISIERLGPIGVVELAERAGRDYTTVSRQVAKLEKLGLIIRQHNVIDR
                     RIREAVISRTGKAMTERIDAAREQMGNVVFKDWPQDKIDIFVRLMQKFADAMDSDASM
                     PE"
     gene            600..1762
                     /locus_tag="OPV72_004316"
                     /pseudo
     CDS             600..1762
                     /locus_tag="OPV72_004316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460506.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent monooxygenase"
     gene            1752..2993
                     /locus_tag="OPV72_004317"
     CDS             1752..2993
                     /locus_tag="OPV72_004317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR9916447.1"
                     /translation="MNTNVYENTDSETITPLNKRRILPVFLLVGLYAASTAAVMSVLP
                     FYIREMGGSPLIIGIIIATEAFSQFCAAPLIGHLSDRVGRKRILIVTLAIAAISLLLL
                     ANAQCILFILLARTLFGISAGNLSAAAAYIADCTHVRNRRQAIGILTGCIGLGGIVGA
                     GVSGWLSRISLGAPIYAAFILVLGAALVAIWGLKDPSTTSRTTDKIASFSARAILKMP
                     VLRVLIIVMLCHFFAYGMYSSQLPVFLSDTFIWNGLPFGPKALSYLLMADGVINIFVQ
                     LFLLGWVSQYFSERKLIILIFALLCTGFLTAGIATTIPVLIFAIVCISIADALAKPTY
                     LAALSVHVSPARQGIVIGTAQALIAIADFISPVLGGFVLGYALYGVWIGIAISVAIIG
                     LVTAMIYLSKSSPLIAKPETE"
BASE COUNT          683 a          800 c          714 g          802 t
ORIGIN      
        1 actttgctgg ctatttaatt aatgcagtag catggacgat cagatttgac cgcccttttc
       61 ttttgcttat tccggcattg aagcatcgct atccattgca tcggcaaact tttgcattaa
      121 ccgaacaaag atatcaattt tatcctgagg ccagtcttta aaaacaacgt tgcccatttg
      181 ctctcgcgca gcgtctatac gctccgtcat cgcctttcct gtccgggaga taacggcctc
      241 gcgtatacga cgatcgatga cattatgttg ccgtattatc aatcccaact tctccagttt
      301 ggcgacctgt cggcttaccg tcgtataatc acgaccggca cgttcggcta actcaacaac
      361 gccaatcggc cctaaacgtt cgatactaat aaggatcgaa aatagcgcgc gatcgagttg
      421 aatccccgcc tctgcaatta atttctcatc attacgaggc cggttgagcg cgctcaccac
      481 gcgaatcaac gcaccgtgaa gtgccttcat ttgctcggaa atatgtgtat cttgcacatt
      541 tttattttct gacatagcat gtctcctctt atgtgcataa tacacatatt ggagagacga
      601 tgacaacata caccactaca gatgtactga tctgcggcgc tggcgttacc gggcttactt
      661 tagccatcga actggcgcgt cacggggtct catttcgcct gattgagaaa agagcgacgc
      721 cttttaccgg ttcccgcgat aaaggtattc agccgcgaac gcaagaaatc ttcgaggata
      781 ttgggatact caataaagtg gtcgccgccg gcgggctcta tccccgatta cgaacctacc
      841 gtcatgacgg aagctacgta gattcagata ttgcgcataa tacaaaaccg acccacgccg
      901 aaccctacca tctgccattg atggttccac agaacgtgac agaaacgatt atgcgggagc
      961 aattaaaagc atggggacat cgggtggagt tcggctgcga gttacgacat tttgcgcaaa
     1021 ccccacgcac ggtcaccgcg tatgttgccg ggccaactgg agaagaggtc atcatcgcgc
     1081 attatttgat aggcgcggat ggcggcggaa gctttgtcag aaagaaatta ggcgtcagct
     1141 tccccggccg tacgttggga atccatgcgc ttgtggctga cgcttcactt accagggatg
     1201 gaaaatggca gcctcgctac ggggcgcagg agaagagctt ctcgatagct atgaacagga
     1261 acgccgcccg gtagccgaat cactgctcca cctttctacc cgattacttg actctcaaaa
     1321 acagggtggc atcaaacgag aacgcgacgt tcaacaactt gacatccagt ataccaactc
     1381 ccccttagcc cacacgttgc ccgaacgtca gcatgggtta caagcgggag aaagagctcc
     1441 ggatgctcct cttttgggcg ccggcggcca atcattacga ttatttcagt tactccaggg
     1501 tccggactgg aatctgttgg cctacgaaac ccacggtaag gtcatcgatg cgcggcgagg
     1561 tctgcgtatt catcacattg gcgagcagga cgagctcatc gataccctgg ggcacttccg
     1621 ggagtcctat catctggccc cgggtcaatg cgtgctgatc cgacccgatg gctatgtcgg
     1681 cgcattcttt cacggcaaac agagcaacga tattgaaaat tatctctctc gttttgccat
     1741 agggattaaa gatgaatact aatgtctatg agaacaccga cagcgaaact atcaccccgc
     1801 tcaacaagcg gcgtattttg cctgttttcc tgcttgtcgg cctttacgcc gccagtacag
     1861 cggctgtgat gtcggtactg cctttttata tccgcgagat gggcggttcg ccgcttatca
     1921 ttggaatcat catcgccact gaggctttta gccaattttg tgcagcgccc ctgattggcc
     1981 acctttccga tcgcgttggc cgcaagcgaa tactgattgt cacgctggct attgcggcga
     2041 taagtttact attactcgcc aacgcgcaat gtatcctgtt tatcctgctc gcccgcacgc
     2101 tttttggcat tagcgccggg aatttgtcag ccgccgcagc ctatattgcc gattgtacgc
     2161 acgtcagaaa tcggcgccag gcaatcggta tcctcacagg ctgcattggt ttaggcggta
     2221 ttgtcggggc aggcgtttcc gggtggctat cgcgtatcag tctgggtgcg ccgatctacg
     2281 ccgcctttat acttgtcctt ggggctgccc tggtcgcgat ttgggggtta aaagaccctt
     2341 ccacaacatc acgtaccaca gataaaatag cgtcgttctc tgcccgcgct attttaaaga
     2401 tgccagtcct tcgcgtctta atcatcgtaa tgctttgtca tttcttcgcc tatggcatgt
     2461 actcttcaca attacctgtt tttctttctg acaccttcat ctggaatggg cttccctttg
     2521 ggccaaaagc gttaagctat ctgttaatgg cggacggggt tattaatatt ttcgttcagc
     2581 tatttctgtt aggttgggtg agccaatatt tttcggagcg aaagctaatt atcctcatct
     2641 tcgcccttct ttgtactgga tttctcactg cgggtatcgc cacgaccata ccagtgctta
     2701 tttttgctat cgtttgtatt agcatcgctg atgcgctagc caaacccact tatcttgccg
     2761 ccttgtccgt ccatgtatcg cctgcccgac aaggtatcgt catcggaacg gcgcaggcat
     2821 taatcgcaat cgctgatttt atatcccccg tattgggcgg atttgtcctg ggttatgccc
     2881 tgtatggcgt ctggatcggt atagctatct ctgtcgccat tattggtctg gtgacggcaa
     2941 tgatttacct ttcaaaaagt tcaccgctaa tagcgaaacc agaaacagaa taatgtgac
//
LOCUS       DAJVBX010000299         2950 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.300, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000299 DAJVBX010000000
VERSION     DAJVBX010000299.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2950)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2950)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2950
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.300"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            34..426
                     /gene="sicP"
                     /locus_tag="OPV72_004318"
     CDS             34..426
                     /gene="sicP"
                     /locus_tag="OPV72_004318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperone SicP"
                     /protein_id="HCR9916448.1"
                     /translation="MQAHQDIIANIGEKLGLPLTFDDNNQCLLLLDSDIFTSIEAKDD
                     IWLLNGMIIPLSPVCGDSIWRQIMVINGELAANNEGTLAYIDAAETLLFIHAITDLTN
                     IYHIISQLESFVNKQEALKNILQEYAKV"
     gene            413..2044
                     /gene="sptP"
                     /locus_tag="OPV72_004319"
     CDS             413..2044
                     /gene="sptP"
                     /locus_tag="OPV72_004319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system effector
                     GTPase-activating protein SptP"
                     /protein_id="HCR9916449.1"
                     /translation="MLRYDERKLNNLTLSSFSKSGVSSDTRLYIAKENTDKAYVAPEK
                     FSSKVLTWLGKMPLFKNTEVVQKHTENIRVQNQKILQTFLQALTEKYGEKAVNNALYM
                     SSINMNKPLTQRLVVQITECVKGADGGFINLIKNKDNVGVMNAALVIKGGDTKVTEQN
                     NDVGAESKQPLLDIALKGLKRTIPQLEQMDGNSLRENFQEMASGNGPLRSLMTNLQSL
                     NKIPEAKQLNDYVTTLKNIQIGADRFSQWGTCGGEVERWIDKASTHELTQAVKKIHVI
                     AKELKNVTAELEKIKAGASMPQTMSGPTLGLARFAVSSIPINQQTQVKLSDGMPVPVN
                     TLTFDGKPVALAGSCPKNTPDALEAHMKMLLEKECSCLVVLTSEDQMQAKQLPAYFRG
                     SYTFGEVHTNSQKVSSASQGGAIDQYNMQLSCGEKRYTIPVLHVKNWPDHQPLPSTDQ
                     LEYLADRVKNSNQNGAPGRSSSDKHLPMIHCLGGVGRTGTMAAALVLKDNPHSNLEQV
                     RADFRNSRNNRMLEDASQFVQLKAMQAQLLMTTAS"
     gene            complement(2098..2580)
                     /gene="iagB"
                     /locus_tag="OPV72_004320"
     CDS             complement(2098..2580)
                     /gene="iagB"
                     /locus_tag="OPV72_004320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system invasion protein
                     IagB"
                     /protein_id="HCR9916450.1"
                     /translation="MHYFFIIVIWLLSINTAWADCWLQAEKMFNIESELLYAIAQQES
                     AMKPGAIGHNRDGSTDLGLMQINSFHMKRLKKMGISEKQLLQDPCISVIVGASILSDM
                     MKIYGFSWEAVGAYNAGTSPKRSDIRKRYAKKIWENYRKLKEMSAEEKNKRLSIAVNK
                     "
     gene            complement(2598..>2950)
                     /locus_tag="OPV72_004321"
     CDS             complement(2598..>2950)
                     /locus_tag="OPV72_004321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461797.1"
                     /note="IagA; HilA; activates the expression of invasion
                     genes and activates the expression of prgHIJK which is
                     part of the pathogenicity island 1 type III secretion
                     system; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCR9916451.1"
                     /translation="QDNPILLSMQVMFLSLKGKHELARKLTKEISTQEITGLIAVNLL
                     YAEYCQNSERALPTIREFLESEQRIDNNPGLLPLVLVAHGEAIAEKMWNKFKNEDNIW
                     FKRWKQDPRLIKLR"
BASE COUNT          924 a          574 c          640 g          812 t
ORIGIN      
        1 cttgtaaaag atataattaa agaggaaagt aaattgcaag cacaccagga tattatcgct
       61 aatattggtg agaaattggg tttaccgctc acttttgatg acaacaatca gtgcttatta
      121 ctactcgata gcgatatttt tacgtctatt gaagctaaag atgatatctg gttattgaac
      181 ggtatgatta taccgctatc gcctgtttgt ggcgattcta tctggcggca gattatggtg
      241 attaatggtg aactggctgc gaataatgaa ggtacgttag cgtatattga tgccgcagag
      301 acgttgttgt ttatacatgc aattaccgat ctgacaaata tttatcatat catatcgcag
      361 cttgagtcat ttgtgaataa gcaggaagcg ctcaaaaaca tactacagga atatgctaag
      421 gtatgatgag aggaagttga ataatttaac attgtcttca ttttcaaaat ctggcgtgtc
      481 gagtgatacc cggctatata ttgctaagga aaatactgat aaggcatatg ttgcgcctga
      541 aaaattttcg tcaaaagtat taacctggct tggaaaaatg cccttattta aaaacactga
      601 agtggtgcaa aaacacacgg aaaatatcag agtacagaac caaaagattt tacagacatt
      661 tctccaggca ttaacggaaa aatatgggga aaaagcggtc aataatgctt tgtacatgtc
      721 cagtataaat atgaacaaac cccttaccca acgtttagta gtgcagatca cggagtgtgt
      781 aaaaggtgct gacggagggt ttataaatct tattaagaac aaggataatg ttggtgtcat
      841 gaatgccgct ttagtcataa aaggcggcga tacaaaagtg acagaacaaa ataacgatgt
      901 tggtgcagaa agtaagcaac ctttactcga tatcgcgcta aagggactta agagaacaat
      961 accgcaactg gaacaaatgg atggaaatag cctgcgagaa aacttccagg agatggcttc
     1021 aggtaacggc ccgctgcgtt cattaatgac gaatttacag agtttaaata aaattccaga
     1081 ggctaaacaa cttaatgatt atgttacaac gttaaaaaat attcagatag gagcagacag
     1141 gttctcacaa tggggaacct gtgggggaga ggttgagagg tggattgata aagcctctac
     1201 tcatgaatta acccaagcgg taaaaaaaat tcacgttatt gctaaagaac tgaaaaacgt
     1261 tacagctgaa cttgagaaaa taaaagccgg tgcgtcaatg ccacagacga tgagcggacc
     1321 gacactgggc ctggcacggt ttgcggtcag cagcattccc attaatcagc aaacccaggt
     1381 gaaactgagc gatggaatgc ctgtgccagt gaatacgtta acttttgacg gtaagcctgt
     1441 ggcattagcc ggttcgtgcc caaaaaatac gccggatgcg ctggaagcgc atatgaaaat
     1501 gcttcttgaa aaagaatgtt cgtgcctggt ggtgttaacg tcggaagatc agatgcaggc
     1561 aaaacaatta ccagcctatt tcagagggag ctacaccttt ggcgaggtgc ataccaacag
     1621 ccaaaaagtg agctcagcca gtcagggagg agcgatagac caatacaata tgcaactgtc
     1681 ctgcggggaa aagcggtata caatcccggt attgcatgtg aaaaattggc cagatcacca
     1741 gccgttaccg tctactgatc agttagaata cctggcggat agggtgaaaa atagtaacca
     1801 aaatggcgcg ccggggcgta gttcatcaga taagcattta ccgatgattc attgtctggg
     1861 cggagtggga agaaccggaa cgatggcggc ggctcttgta cttaaggata atcctcatag
     1921 taatctggag caggtacgtg cagatttccg gaattcacgg aacaatagaa tgctggaaga
     1981 cgcctcacag tttgtacaac taaaagcaat gcaagcccag ttgcttatga cgacggcaag
     2041 ctgataaaaa catagcttac ttttagaatt atctgaaagt aagctattcc tgtataatta
     2101 tttgtttacc gcgatagaaa gtcttttgtt tttctcttct gctgacatct cttttaattt
     2161 tctgtaattc tcccaaattt ttttagcata acgtttcctt atatccgatc gtttcggcga
     2221 cgtcccggca ttataagcgc caacggcctc ccagctaaaa ccgtagattt tcatcatatc
     2281 tgataaaatg gatgcgccca caatgacaga aatgcaggga tcctgtaaca actgtttttc
     2341 actaatcccc atttttttca gccttttcat atggaagctg ttaatttgca tcaggccaag
     2401 atcggttgaa ccatctcggt tatgaccaat ggcgccaggt ttcatcgccg attcctgctg
     2461 ggcgatagcg taaagtagtt cggattcaat attgaacatt ttttcagcct gaagccagca
     2521 atcagcccat gccgtattta tgctaagcaa ccagattacg atgataaaaa aataatgcat
     2581 atctcctctc tcagatttta ccgtaattta atcaagcggg gatcctgttt ccatcttttg
     2641 aaccaaatat tgtcttcgtt tttaaattta ttccacattt tctcggcaat agcttcgccg
     2701 tgggcaacca gcactaacgg taataatccc ggattattat ctatacgctg ttcactttcc
     2761 agaaattctc ttatcgtcgg taaggcacgc tcactattct gacaatattc agcgtaaaga
     2821 agattaacag caataagtcc tgttatttcc tgcgtggata tttctttagt taattttcgt
     2881 gccagttcat gtttaccttt aagcgaaaga aacataacct gcatacttaa taatattgga
     2941 ttatcctgca
//
LOCUS       DAJVBX010000300         2914 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.301, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000300 DAJVBX010000000
VERSION     DAJVBX010000300.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2914
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.301"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..85
                     /locus_tag="OPV72_004322"
     CDS             <1..85
                     /locus_tag="OPV72_004322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916452.1"
                     /translation="VEVGNVAVRNNTDERQTRYRVGLQYHF"
     gene            368..1648
                     /locus_tag="OPV72_004323"
     CDS             368..1648
                     /locus_tag="OPV72_004323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR9916453.1"
                     /translation="MIAKFFPWYSEITRPQKNALFSAWLGYVFDGFDFMLIFYIMYLI
                     KADLGLTDMEGAFLATAAFIGRPFGGALFGLLADKFGRKPLMMWSIVAYSVGTGLSGL
                     ASGVIMLTLSRFIVGMGMAGKYACASTYAVESWPKHLKSKASAFLVSGFGIGNIIAAY
                     FMPSFAEAYGWRAAFFVGLLPVLLVIYIRARAPESKEWEEAKLSGLGKHSQSAWSVFS
                     LSMKGLFNRAQFPLTLCVFIVLFSIFGANWPIFGLLPTYLAGEGFDTGVVSNLMTAAA
                     FGTVLGNIVWGLCADRIGLKKTFSIGLLMSFLFIFPLFRIPQDNYLLLGACLFGLMAT
                     NVGVGGLVPKFLYDYFPLEVRGLGTGLIYNLAATSGTFNSMAATWLGITMGLGAALTF
                     IVAFWTATILLIIGLSIPDRLKARRERFQSTKEF"
     gene            1659..2765
                     /locus_tag="OPV72_004324"
     CDS             1659..2765
                     /locus_tag="OPV72_004324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCR9916454.1"
                     /translation="MMTKYGVIGTGYFGAELARFMSKVEGAKITAIYDPVNAAPIAKE
                     LNCVATSTMEALCTHPDVDCVIIASPNYLHKAPVIAAAKAGKHVFCEKPIALNYQDCK
                     DMVDACKEAGVTFMAGHVMNFFHGVRHAKALIKAGEIGEVTQVHTKRNGFEDVQDEIS
                     WKKIRAKSGGHLYHHIHELDCTLFIMDETPSLVSMAAGNVAHKGEKFGDEDDVVLITL
                     EFESGRFATLQWGSSFHYPEHYVLIEGTTGAILIDMQNTAGYLIKAGKKTHFLVHESQ
                     AEDDDRRNGNISSEMDGAIAYGKPGKRTPMWLSSIMKLEMQYLHDVINGLEPGEEFAK
                     LLTGEAATNAIATADAATLSSNEGRKVKLTEILG"
BASE COUNT          745 a          576 c          743 g          850 t
ORIGIN      
        1 cgttgaggtc ggaaatgtag cggtgagaaa taataccgat gagagacaga cccgttatcg
       61 cgttggatta caataccact tttgagaaag gttaaagagt tactgtacta atctttgctt
      121 agtattcata tcgataatct tatagcccgt agctacgtta cagaacgtta gactttgtct
      181 tgagtattca cgtccttaac gtagctacga acaaggatga taaacaatga atatacgcct
      241 tacatagcta cgatctcagg cggttgtcgg aaagtgccgg ttgatagtgt cttattcggc
      301 aattgatatg acttaaaaat taattccgta agcatttcag acggtaacag caaataaggg
      361 ttttattgtg atagcaaaat tcttcccgtg gtatagcgag ataacacgtc cacaaaaaaa
      421 tgctttattt tcagcatggc tgggttacgt ttttgatggc ttcgacttta tgctgatttt
      481 ctacattatg tatctgatca aggctgactt aggattgaca gatatggagg gcgcattcct
      541 tgccacagcg gcctttattg ggcgaccatt tggcggggcg ctatttggtc tgctggcaga
      601 caaatttggc cgtaagccgt taatgatgtg gtcgatagtt gcctattctg taggtacagg
      661 gttaagtggc ctggcttccg gtgtaattat gctgacgctt agtcgtttta ttgtcggtat
      721 ggggatggcg gggaagtatg cttgcgcttc tacttatgcc gtggaaagtt ggccaaagca
      781 tttaaaatct aaagcgagcg catttctggt ttcaggtttc ggtattggta acatcatagc
      841 agcctatttt atgccgtcat ttgccgaagc gtatggttgg cgtgctgctt tttttgtcgg
      901 tttgctaccc gttcttttag taatctacat ccgggccagg gctcctgaat ctaaagagtg
      961 ggaagaagcc aaactcagtg gtctcggaaa gcattcacaa agtgcctggt cagttttctc
     1021 tttgtcaatg aaagggctat ttaatcgagc tcaatttcca ctgacattat gtgtatttat
     1081 tgttctgttc tctattttcg gcgcaaactg gccgatcttt ggtctactgc ctacatattt
     1141 ggcgggagag ggctttgata cgggcgtggt ctctaattta atgacggcgg cggcattcgg
     1201 cactgtattg ggaaatatcg tttggggtct gtgcgcagat agaattggtt tgaagaaaac
     1261 gttcagcatt ggtcttctca tgtccttttt attcattttc ccgttattca gaattccgca
     1321 agataattat ttactgctgg gcgcatgttt attcggttta atggcgacta acgtaggtgt
     1381 tggcgggctg gttcccaaat ttctctacga ctactttcct cttgaggttc gtggtttggg
     1441 taccgggctt atttataatc ttgctgcgac atcaggcaca ttcaattcaa tggcggcgac
     1501 ctggcttgga ataacaatgg ggctaggcgc tgcgctaacg ttcattgttg ctttctggac
     1561 cgcaacaatt ctactcatta ttggcctatc cattccggat agactaaaag cacgtcgtga
     1621 aaggtttcag tcaacaaaag aattttaata gaggataaat gatgacgaaa tacggtgtta
     1681 taggtacagg ttattttggc gctgaactgg cgcgatttat gtctaaggtt gaaggggcga
     1741 aaatcactgc gatttacgat ccggtaaatg cggctccgat agcgaaagag ctgaactgtg
     1801 tcgccacttc aacgatggag gcgctttgta cccatcctga tgtggattgc gtaattattg
     1861 cttcaccaaa ttacttacat aaagcgccgg tcattgcggc ggctaaagcg ggtaaacacg
     1921 tgttttgtga aaaacctatc gccttaaatt accaggattg taaggatatg gttgatgcct
     1981 gcaaagaagc tggtgttacc tttatggcgg gtcacgttat gaactttttt cacggggttc
     2041 gccacgctaa agcgctcatc aaagccggtg aaatcggtga agttacacaa gttcacacta
     2101 aacgtaatgg ttttgaagac gtgcaggatg agatctcatg gaagaagatt cgcgcaaagt
     2161 caggtgggca tctgtaccat cacattcacg agctagattg tacactgttc atcatggatg
     2221 aaaccccatc cctggtttca atggcggcgg ggaatgttgc gcacaaaggt gaaaaatttg
     2281 gtgatgaaga tgatgttgtc ctaatcaccc ttgagtttga aagcggtcgt ttcgcgacac
     2341 ttcagtgggg atcatcgttc cactaccctg agcactatgt attaattgag ggcacgacag
     2401 gtgcaattct cattgatatg caaaacacgg ctggttatct aataaaagcg ggcaaaaaaa
     2461 cacactttct tgtgcatgaa agccaggcgg aggatgatga tcgtcgcaac ggtaacatat
     2521 ccagcgagat ggatggcgca atcgcttatg gtaaacccgg taaacgtacg ccgatgtggc
     2581 tctcatcaat tatgaaactg gagatgcagt acttgcatga tgtgataaac ggtctggagc
     2641 caggcgagga gtttgctaaa ttgctaacgg gagaagcggc gacaaatgcc attgctaccg
     2701 ctgatgctgc gacgctttct tcaaacgagg ggcgcaaagt taaactcact gaaattcttg
     2761 gctaaaattt aaagccggat ggtggtgtta ttggccggtg gcgctgcgct tatgtagact
     2821 ggataaggcg cccgtgaact gtgccgccat ccggcaatgg acgggggctt aatgcgaaaa
     2881 aaagcccgta cattcgtacg agctctttct taaa
//
LOCUS       DAJVBX010000301         2840 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.302, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000301 DAJVBX010000000
VERSION     DAJVBX010000301.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2840)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2840)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2840
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.302"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(138..479)
                     /gene="sigE"
                     /locus_tag="OPV72_004325"
     CDS             complement(138..479)
                     /gene="sigE"
                     /locus_tag="OPV72_004325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system chaperone SigE"
                     /protein_id="HCR9916455.1"
                     /translation="MESLLNRLYDALGLDAPEDEPLLIIDDGIQVYFNESDHTLEMCC
                     PFMPLPDDTLTLQHFLRLNYASAVTIGADADNTALVALYRLPQTSTEEEALTGFELFI
                     SNVKQLKEHYA"
     gene            complement(496..2181)
                     /gene="sopB"
                     /locus_tag="OPV72_004326"
     CDS             complement(496..2181)
                     /gene="sopB"
                     /locus_tag="OPV72_004326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system effector
                     inositol phosphate phosphatase SopB"
                     /protein_id="HCR9916456.1"
                     /translation="MQIQSFYHSASLKTQEAFKSLQKTLYNGMQILSGQGKAPAKAPD
                     ARPEIIVLREPGATWGNYLQHQKTSNHSLHNLYNLQRDLLTVAATVLGKQDPVLTSMA
                     NQMELAKVKADRPATKQEEAAAKALKKNLIELIAARTQQQNGLPAKEAHRFAAVAFRD
                     AQVKQLNNQPWQTIKNTLTHNGHHYTNTQLPAAEMKIGAKDIFPSAYEGKGVCSWDTK
                     NIHHANNLWMSTVSVHEDGKDKTLFCGIRHGVLSPYHEKDPLLRQAGAENKAKEVLAA
                     ALFSKPELLNRALEGEAVSLKLVSVGLLTASNIFGKEGTMVEDQMRAWQSLTQPGKMI
                     HLKIRNKDGDLQTVKIKPDVAAFNVGVNELALKLGFGLKASDSYNAEALHQLLGNDLR
                     PEARPGGWVGEWLAQYPDNYEVVNTLARQIKDIWKNNQHHKDGGEPYKLAQRLAMLAH
                     EIDAVPAWNCKSGKDRTGMMDSEIKRELISFHQTHMLSAPGSLPDSGGQKIFQKVLLN
                     SGNLEIQKQNTGGAGNKVMKNLSPEVLNLSYQKRVGDENIWQSVKGISSLITS"
     gene            2513..2683
                     /locus_tag="OPV72_004327"
     CDS             2513..2683
                     /locus_tag="OPV72_004327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlcI/YnfO family protein"
                     /protein_id="HCR9916457.1"
                     /translation="MPAKPRTSKTVTKNIRFSYSMLEQIEFALKSEKTRNFSAWVKEA
                     CREKLCNTGHKL"
     gene            complement(2684..2794)
                     /locus_tag="OPV72_004328"
     CDS             complement(2684..2794)
                     /locus_tag="OPV72_004328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_447525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916458.1"
                     /translation="MTLQTNISRETKAAKTQEVYKHVVLFKMAAPSYIRR"
BASE COUNT          711 a          631 c          632 g          866 t
ORIGIN      
        1 tgctcccgca aacagagcaa aatgagaaag aggaacgttt gccctttaca tttccaccaa
       61 agattctggt tttgtctctt gtaaagggca tacgtatcgc gttttatctc attaagaaag
      121 tatgttgacg tattaaatta tgcataatgc tctttcaatt gcttcacgtt tgaaatgaat
      181 aattcaaaac cagtgagcgc ctcttcttcg gtactggttt gcggcaagcg ataaagcgcc
      241 actaaagcag tattgtctgc atcagcgccg atagtgacgg cgctggcgta gttaagacgt
      301 aaaaaatgct gcaaagtcag agtgtcgtca ggcagtggca taaagggaca gcacatttcc
      361 agtgtatgat cggattcatt aaaataaacc tgtatcccat catcaatgat aagcagtggc
      421 tcatcttctg gcgcatccag gcctaacgcg tcatataaac gatttaatag actttccata
      481 tagttacctc aagactcaag atgtgattaa tgaagaaata ccttttactg actgccaaat
      541 attttcatcc ccaactcgtt tttgatagga aagattgagc acctctggcg ataaattttt
      601 cattactttg tttcccgccc cgcccgtatt ttgtttctga atctccaggt taccgctatt
      661 cagtaatact ttttggaaaa ttttctgtcc accgctatcc ggaagactac caggcgcact
      721 taacatatgg gtctgatgga aagaaatgag ctctcgcttg atttctgaat ccatcatccc
      781 tgtacgatct ttgccgcttt tacaattcca ggcgggcacc gcgtcaattt catgggctaa
      841 catggcaagg cgttgtgcga gtttataggg ttcgccgcca tctttatgat gttggttatt
      901 tttccagata tccttaatct ggcgcgctaa tgtattgacg acctcataat tatccgggta
      961 ttgcgccagc cattcgccaa cccagccacc tggtctggct tcagggcgta aatcattgcc
     1021 taataactga tgtagcgctt cggcattata gctatctgat gctttaaggc caaagccgag
     1081 cttgagcgcc agctcattaa cacccacatt aaatgcggcg acgtccggtt ttatttttac
     1141 cgtctgtaga tcgccatctt tattgcggat ttttaaatga atcatttttc ccggctgggt
     1201 caacgattgc catgcgcgca tttgatcctc gaccatagtt ccctctttgc cgaaaatatt
     1261 cgacgcggtg agtaacccga cggataccag tttcaggctt accgcttcgc cctctaaggc
     1321 tctgttaagc aactcaggtt tactaaaaag tgccgcagct aatacttctt tggctttgtt
     1381 ttcagcgccg gcctgacgca gaagcggatc tttttcatga tagggggaaa gcacaccatg
     1441 acgtatcccg caaaaaagcg ttttatcttt accgtcctca tgcacactca ccgtggacat
     1501 ccacaaatta ttggcgtgat gaatattctt ggtatcccaa ctgcatacgc cctttccctc
     1561 ataagcactg ggaaagatat cttttgcgcc gattttcatc tctgcggcag ggagctgcgt
     1621 gttggtatag tgatgcccgt tatgcgtgag tgtatttttt atggtttgcc agggctggtt
     1681 attgagctgc ttgacctgag catctctaaa cgctactgcc gcaaagcgat gagcttcttt
     1741 tgcaggtaag ccattttgct gctgagtgcg tgctgcaata agttcgataa gatttttctt
     1801 caatgctttt gccgcagctt cttcttgttt tgttgctggc cggtccgctt taactttggc
     1861 taactccatt tggtttgcca ttgacgttag aaccgggtct tgtttaccca gaacggttgc
     1921 cgcgacggta agaagatcgc gctgtaagtt atagaggtta tgcagcgagt ggttagacgt
     1981 cttctgatgc tgtagataat tcccccatgt cgcgccaggt tctcgcagga caataatttc
     2041 cgggcgagcg tcgggcgctt tagccggcgc tttgccctgg cctgagagaa tctgcattcc
     2101 gttgtataag gttttttgta ggcttttaaa agcctcctgg gtttttagtg aagctgagtg
     2161 atagaagctc tgtatttgca tagcgttttt aatattcctg aataggggag tgggaacatt
     2221 caacagggtt aacaatcttt taaaaggatg tgacttttat gcaccaggaa ctttaaaaaa
     2281 atgtcctttt taatgaggaa acgcttctga tcaggcgggg aggcatcctg acgtccatac
     2341 gtagtggcga tcatggggga gatcggtaca tcaaatgttc ataaaatcta caaacttcac
     2401 aatttagggc acaactttta ttgaaaaccc accttcttga ttcagatcaa attcaccgat
     2461 ttactcctgc gtaaagtaac ggcgttacat caaatgttat acaggtgtgt gtatgccagc
     2521 aaagccccgg acgagtaaga ccgtgacgaa gaatattcgt ttttcctatt ccatgcttga
     2581 acagatagaa ttcgcgttga aatctgaaaa gacgcggaat ttttcagcat gggtaaaaga
     2641 ggcctgtcgg gaaaagttat gtaacacggg acataagctg tagttatcgt cttatgtaag
     2701 agggggcggc cattttgaaa agaacaacgt gcttatatac ctcctgggtc tttgccgctt
     2761 ttgtctctct gctgatattt gtctggagtg tcataaacta tcctctctat gaatccataa
     2821 taattattgt cttttatatc
//
LOCUS       DAJVBX010000302         2715 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.303, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000302 DAJVBX010000000
VERSION     DAJVBX010000302.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2715)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2715)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2715
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.303"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            26..712
                     /gene="sopE"
                     /locus_tag="OPV72_004329"
     CDS             26..712
                     /gene="sopE"
                     /locus_tag="OPV72_004329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system guanine
                     nucleotide exchange factor SopE"
                     /protein_id="HCR9916459.1"
                     /translation="MQKQETTLLKEKSTEKNSLAKSILAVKNHFIELRSKLSERFISH
                     KNTESSATHFHRGSASEGRAVLTNKVVKDFMLQTLNDIDIRGSASKDPAYASQTREAI
                     LSAVYSKNKDQCCNLLISKGINIAPFLQEIGEAAKNAGLPGTTKNDVFTPSGAGANPF
                     ITPLISSANSKYPRMFINQHQQASFKIYAEKIIMTEVAPLFNECAMPTPQQFQLILEN
                     IANKYIQYTP"
     gene            complement(910..1317)
                     /locus_tag="OPV72_004330"
     CDS             complement(910..1317)
                     /locus_tag="OPV72_004330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HCR9916460.1"
                     /translation="MSEYYYSFKEKGFFWQPDTESDNYPDDLIPLTDEYYRELMQGQV
                     DGKYIEHRKGGPVLVEHREYTPEELVAQAEARKAELLAEAESVIAPLARAVKLKIATD
                     EEIKRLEAWELYSVMVNRVDTANPDWPEKPAQI"
     gene            complement(1324..>2715)
                     /locus_tag="OPV72_004331"
     CDS             complement(1324..>2715)
                     /locus_tag="OPV72_004331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCR9916461.1"
                     /translation="QVIPETEGGWWIREVGLFDETGALIAVGNCPESYKPQLTEGSGR
                     TQTVRMVLITSSTDNITLKIDPAVVLATRKYVDDKALELKVYVDDLMAKHLAAPDPHS
                     QYAQKDSPTLTGIPKVPTPAAGNSTKQIANTEFVASSIAAMVDSAPAALDTLNELAAA
                     LGNDPNFATTMLNALGGKQPLDNTLTNLSGKDVAGLLAYFGLGETINRAADALQKSQN
                     GADIPDKPRFVQNIGLKETLNPTKRVSIGNIGTGVFDGSTPCINIGDSDSGFIGSADG
                     VLDIYCNGAKVGYINGNGLHMLTDIHFDNASMTTNGDIFSSVWGDNWLSIWITNQLNT
                     RGTIDWINSELAIRDNNINTRATIDYVNQTFARKNTGSIQDWGWILDDSTGFIMQWGT
                     LGNSNGTYNFPRAFPVGCFAVFVTNTNAQGTQVDNAFGYPVSNSQFFAATKSSGMANL
                     VNNFPVAWFAIGR"
BASE COUNT          728 a          688 c          562 g          737 t
ORIGIN      
        1 aactttatct ccccagaatt ttagaatcca aaaacaggaa accacactac taaaagaaaa
       61 atcaaccgag aaaaattctt tagcaaaaag tattctcgca gtaaaaaatc acttcatcga
      121 attaaggtca aaattatcgg aacgttttat ttcgcataag aacactgagt cttctgcaac
      181 acactttcac cgaggaagcg catctgaggg ccgggcagtg ttgacaaata aagtcgttaa
      241 agattttatg cttcaaacgc tcaatgatat agatattaga ggtagtgcga gtaaagaccc
      301 cgcatacgcc agccagaccc gtgaagctat actatcggca gtttacagca agaataaaga
      361 tcagtgttgt aatttgctca tcagcaaagg gatcaacata gcgccttttc ttcaggaaat
      421 tggcgaagca gcgaaaaatg caggtctgcc cggaacaacc aaaaatgacg tttttacgcc
      481 aagcggcgca ggggccaatc cttttataac tccgttgatt tcatcagcaa acagtaagta
      541 tccacgtatg tttatcaatc aacatcagca ggcatccttt aaaatctatg cggagaagat
      601 cattatgaca gaagttgcac cactgtttaa tgagtgtgct atgccgactc cacagcaatt
      661 ccaactgata ctagaaaaca ttgctaataa atatatacaa tacactccct gaacacagaa
      721 aaaccaaaaa atatgcggag cctcttcctg attaatatga accaatagta tccataattt
      781 tccccaggaa ctaactccgg agctaaaccg tcatttacca gtgctaaaat tatacactca
      841 accatcaaaa aaaatagcca ttgctgctat ataacatata gcagcagtct ctactacata
      901 tctatatttt tatatctgag ctggtttctc cggccagtct gggttagctg tatccacccg
      961 gtttaccatt acgctataaa gttcccatgc ttccagccgt ttaatctctt catctgtggc
     1021 aattttcagt tttaccgccc gcgccagtgg cgcaataact gactctgcct cagcaagaag
     1081 ttccgctttt ctggcttcag cctgtgcaac cagctcttca ggcgtatatt cgcgatgctc
     1141 aaccagtacc gggcctcctt tcctgtgctc gatatatttt ccgtccacct ggccctgcat
     1201 cagctcgcga taatactcat ctgtcagggg aattaaatcg tcagggtaat tatcggattc
     1261 ggtatccggt tgccagaaaa aacctttttc tttaaagctg taataatatt cgctcattga
     1321 tatttatctc ccaatcgcaa accaggctac aggaaaatta ttgaccagat tggccattcc
     1381 tgatgacttg gtggcggcaa aaaactgact gttgctcacc gggtatccga atgcgttatc
     1441 cacctgggtg ccctgagcgt tggtattggt tacaaaaacg gcaaagcaac caacagggaa
     1501 agcgcgcggg aaattgtagg ttccgtttga gttaccaagt gttccccact gcattataaa
     1561 tccggtgctg tcgtccagaa tccagcccca gtcctgaatg ctgccggtat ttttacgggc
     1621 gaaagtctgg ttaacataat caatggtggc gcgggtgttg atgttgttgt cacgaattgc
     1681 cagttcacta ttgatccagt caatcgttcc acgggtattt agctgattag taatccagat
     1741 actcagccag ttatcccccc acactgaact aaaaatgtca ccattagtgg tcatgctcgc
     1801 attatcgaaa tgaatatcag tgagcatgtg taatccgtta ccattgatat aacccacttt
     1861 ggcaccgtta cagtaaatat ccagtacgcc atccgcgctg ccgataaatc cactgtcact
     1921 gtcaccgata tttatacacg gtgtgctgcc gtcaaaaacg ccggttccga tattgcctat
     1981 actcacgcgt tttgtcgggt tcagggtttc ttttaaaccg atattttgta caaaccgcgg
     2041 cttgtcagga atgtctgcac cgttctgtga tttttgtagc gcatcggcgg cacgatttat
     2101 cgtttctcct aaaccgaagt atgcgagaag gccggcgaca tcttttccgc ttaaattcgt
     2161 cagcgtattg tccagcggct gctttccacc aagagcgttt aacatcgttg tggcaaaatt
     2221 cgggtcattc cccagagccg ctgccagctc gttcagcgta tccagtgctg caggcgcaga
     2281 atccaccatt gccgcaatag acgatgccac aaattccgtg ttcgcaatct gtttagtgct
     2341 gttacccgcc gctggcgtcg gtacctttgg aatccctgtg agtgtcgggc tgtccttctg
     2401 cgcatactgt gaatgcgggt ccggcgcagc aagatgcttt gccatcaggt cgtctacata
     2461 taccttcagc tccagcgcct tatcatctac atatttacgg gttgccagca ctactgcagg
     2521 gtcaattttc agggtgatgt tatcggtgct gctggtaatc agtaccatgc gcacggtctg
     2581 cgtacgtccg ctcccttctg tcagctgcgg cttgtagctc tcagggcagt tacccacagc
     2641 gatcagcgca ccggtttcat caaacaggcc aacttcacga atccaccacc cgccctcagt
     2701 ttccgggatt acctg
//
LOCUS       DAJVBX010000303         2592 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.304, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000303 DAJVBX010000000
VERSION     DAJVBX010000303.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2592
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.304"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            155..1786
                     /gene="dcuS"
                     /locus_tag="OPV72_004332"
     CDS             155..1786
                     /gene="dcuS"
                     /locus_tag="OPV72_004332"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     DcuS"
                     /protein_id="HCR9916462.1"
                     /translation="MKHSLPCRALRKRPMKLGTTVILMVSAVLFSVLVVVHLIYFSQI
                     SSMTRDALADKALAVARSLADSPAIREGLKKPPAESGIQPLSEAVSQHNGFLFIVVTN
                     MQGIRYSHPETQRIGQPFKGDDILLALQGKENVAINRGFLAKALRVFTPVYDEHHRQI
                     GVVAIGLELSHVTQQINNSRGSIIWSILFGALVGLLGTYALVKVLKRILFGLEPYEIS
                     TLFEQRQAMLQSIKEGVIAVDGSGEVTLINHAAQALLDYRKTQDDARLSTLSHAWPQV
                     VDISEVLRDGTPRRDEEIIVKGRLLLVNTVPVRSNGEIIGAISTFRDKTEVRQLMQRL
                     DGMVNYADALRERSHEFMNKLHVILGLLHLKSYKQLEAYIIKTANNYQEEIGLLLGKI
                     KSPIIAGFLLSKITRASDFGHSLVISSDSQLPDNNNEDQVTVLITALGNLIENALEAL
                     SQESGGEISVSLHYRHGWLHCEVSDDGPGIEPERIEAIFEKGVSSKGAERGVGLALVK
                     QQVEALGGVISVESEPGIFTQFFVQLPWDGKRTSL"
     gene            1783..2502
                     /gene="dcuR"
                     /locus_tag="OPV72_004333"
     CDS             1783..2502
                     /gene="dcuR"
                     /locus_tag="OPV72_004333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator DcuR"
                     /protein_id="HCR9916463.1"
                     /translation="MINVLIVDDDAMVAELNRRYVAQISGFHCCGTASTLEKAKEFIF
                     NSENHIDLILLDIYMQQENGLDLLPVLHSAGCKSDVIVISSAADAATIKDSLHYGVVD
                     YLIKPFQATRFEEALTGWLRKKTAMEKRQYYEQSELDLLIHGNSSSEQEPRRLPKRLT
                     QQTLRTLCQWIDAHQEQEFSTDELANEVNISRVSCRKYLIWLVNCHILFTSIHYGVTG
                     RPVYRYRVQPEHYSLLKQYCQ"
BASE COUNT          654 a          645 c          681 g          612 t
ORIGIN      
        1 acggtatccg gcgatattaa ttaacgacat gagcaggtag cgccccctgc aagactagac
       61 gggcttttca acactggagc aacatcgcct atgcctttga attagacgcc tcatcaggga
      121 taataacctt acgattcgtc cgctcaggtc cactatgaaa cactccctgc catgccgggc
      181 gttacgcaaa cgccccatga aactcggcac taccgtcatt ctgatggtca gcgccgtttt
      241 gttttcggtg ctcgttgtgg tccatctgat ctatttttcg caaatcagca gcatgacgcg
      301 cgacgcgctg gcagataaag cgctggcggt ggctcgctcg ctggcggact ctccggcaat
      361 tcgcgagggg ctgaaaaaac cgcctgcgga aagcggcatt cagccgctct ccgaagcggt
      421 gagccagcat aatggctttt tgtttattgt ggtgaccaat atgcagggca tccgttattc
      481 gcacccagaa acgcagcgaa tcggtcaacc gttcaaaggc gatgacattc tgctcgcact
      541 gcagggaaag gaaaacgttg ccattaatcg cggctttctt gccaaagcgc tgcgcgtttt
      601 cacaccggtt tatgatgaac accaccgaca gatcggcgtg gtagcgattg gcctggaact
      661 cagtcacgtt acgcagcaga tcaacaatag ccgcggcagt attatctggt ccattctgtt
      721 cggcgctctg gtgggattat taggcaccta tgcgctggtc aaggtgctaa aacgtatcct
      781 gtttggcctc gaaccctatg agatctcaac cctgtttgaa caacgccagg cgatgctgca
      841 gtcaatcaaa gagggcgtaa tcgccgtaga tggtagcggc gaagtcacgt tgattaacca
      901 cgcggcgcag gcgctgctcg attatcgaaa aacacaggat gacgccagat tatccaccct
      961 gagtcatgcc tggccgcagg tggtggacat tagcgaagtg ttgcgtgacg gtacgccgcg
     1021 ccgcgatgaa gagattatcg tcaaaggccg cctgctgctg gtgaataccg ttccggtgcg
     1081 cagcaacggc gaaattatcg gcgcgatatc caccttcagg gataaaacag aagttcgcca
     1141 actgatgcag cggttagacg ggatggtgaa ctacgcggat gcgctccgtg aacgatccca
     1201 cgaattcatg aacaaattac atgtgattct gggattattg cacctgaaga gttataagca
     1261 gcttgaagcg tatattatca agacggccaa taactatcag gaagagatcg gtttgctgct
     1321 gggtaaaata aagtcgccga ttatcgctgg ctttttgctc agtaagatta cccgcgcctc
     1381 tgatttcggg cacagcctgg tgataagcag cgacagccag ttaccggata ataacaatga
     1441 agatcaggtt acggtgctga ttacggcgct gggtaatttg attgaaaacg cgctggaagc
     1501 gttgagccag gaatccggcg gcgaaatcag cgtctcgtta cactaccgtc atggctggct
     1561 gcattgcgaa gtgagcgatg acggtccggg tatcgaacct gagcgcatcg aggcgatttt
     1621 tgaaaaaggc gtctcgtcga aaggcgccga acgcggcgtc ggtttagcgc tggttaaaca
     1681 gcaggttgaa gcgcttggcg gcgtaatttc cgtggagtcc gagcctggga tcttcacaca
     1741 attttttgta cagttaccct gggatggaaa aaggaccagc ctatgatcaa tgtattaatt
     1801 gtcgatgacg atgcgatggt cgcggagtta aatcgccgct atgtcgcgca aatctccggt
     1861 tttcattgtt gtggaaccgc ttcgacgctg gaaaaagcga aagagtttat cttcaacagt
     1921 gaaaatcaca ttgacctaat cctgctggat atctatatgc agcaggaaaa cggattggat
     1981 ctgctgcctg tcctgcacag cgcaggctgc aaaagcgacg ttattgtcat ttcttctgcc
     2041 gctgacgccg ccaccattaa agattcgctt cactacggcg tggtggatta tctgatcaag
     2101 ccttttcagg ccacgcgctt tgaagaagcg ttgaccggct ggctacgtaa gaaaacggcg
     2161 atggaaaaac gccagtatta cgaacagtct gagcttgacc tgctcattca cggtaattca
     2221 tccagcgagc aggagcctcg tcggctgcca aaaaggctga cccagcaaac gctacgcacc
     2281 ttatgccagt ggattgatgc gcatcaggag caggaatttt ctaccgacga gttagccaac
     2341 gaagtgaata tctcgcgcgt ctcctgccgt aaatatctca tctggctggt gaattgccat
     2401 atcttgttta ccagtattca ttacggcgtg accggcaggc cggtttaccg ctaccgcgtt
     2461 cagccggaac attactcttt actgaaacaa tattgtcagt aaggataccg cataaagccg
     2521 acgcgaagcg ttatatcttg gtaacattta ttataacaat gccaataaaa acgctatcac
     2581 attaataaca aa
//
LOCUS       DAJVBX010000304         2516 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.305, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000304 DAJVBX010000000
VERSION     DAJVBX010000304.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2516
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.305"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..>2516
                     /locus_tag="OPV72_004334"
     CDS             <1..>2516
                     /locus_tag="OPV72_004334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="two component system sensor kinase"
                     /protein_id="HCR9916464.1"
                     /translation="AERDAKNLMYQCSLATEIHHNDIFPEVSRHLSVGPSNCTPTLNG
                     EKHRLFLQSSDIDEKSFRRDSFILNHKNEISLLSTDNPSDYSTLQLLTRKSFPLYPTH
                     AGFYWSEPEYINGKGWHASVAVADQQGVFFGVMVKLPDLISKSHLPLDDSIRVWLDQN
                     NHLLPFSYIPQKIRTQLENVTLHDGWQQIPGFLILRTTLHGPGWSLVTLYPYGNLHNR
                     ILKTILQQIPFTLTALVLMTSAFCWLLHRSLAKPLWRFVDIINKTATAPLSTRLPAQR
                     LDELDSIAGAFNQLLDTLQVQYDNLENKVAERTQALNEAKKRAEQANKRKSIHLTVIS
                     HELRTPMNGVLGAIELLQTTPLNIEQQGLADTARNCTLSLLAIINNLLDFSRIESGHF
                     TLHMEETALLPLLDQAMQTIQGPAQSKKLSLRTFVGQHVPLYFHTDSIRLRQILVNLL
                     GNAVKFTETGGIRLTVKRHEEQLIFLVSDSGKGIEIQQQSQIFTAFYQADTNSQGTGI
                     GLTIASSLAKMMGGNLTLKSVPGVGTCVSLVLPLQEYQPPQQIKGTLSAPFCLHRQLA
                     CWGIRGEPPHQQNALLNAELLYFPGKLYDLAQQLILCTPNIPIINNLLPPWQLQILLV
                     DDADINRDIIGKMLVSLGQHVTIAASSNEALTLSQQQRFDLVLIDIRMPEIDGIECVQ
                     LWHDEPNNLDPDCMFVALSASVATEDIHRCKKNGIHHYITKPVTLATLARYISIAAEY
                     QLLRNIELQEQDPSRCSALLATDDMVINSKIFQSLDLLLADIENAVSAGKKIDQLIHT
                     LKGCLGQIGQTELVCYVIDIENRVKMGKIIALEELTDLRQ"
BASE COUNT          758 a          567 c          517 g          674 t
ORIGIN      
        1 ggctgaacgt gacgctaaaa atttaatgta tcaatgctca ttagcgactg agattcatca
       61 taatgatatt ttccctgagg tgagccggca tctttctgtc ggtccttcaa attgcacgcc
      121 gacgctaaac ggagagaagc atcgtctctt tctgcagtcc tctgatatcg atgaaaaaag
      181 ctttcgtcgc gatagtttta ttcttaacca taaaaatgag atttcgttat tatctactga
      241 taacccttca gattattcaa ctctacagct tttaacgcga aaaagctttc ctttataccc
      301 aacccatgcc gggttttact ggagtgaacc agaatacata aacggcaaag gatggcacgc
      361 ttccgttgcg gttgccgatc agcaaggcgt attttttggg gtgatggtta aacttcctga
      421 tctcatttct aagagccacc taccattaga tgatagtatt cgagtatggc tggatcaaaa
      481 caaccactta ttgccgtttt catacatccc gcaaaaaata cgtacacagt tagaaaatgt
      541 aacgctgcat gatggatggc aacaaattcc cggatttctg atattacgca caactttgca
      601 tggccccgga tggagtctgg ttacgctgta cccatacggt aatctacata atcgcatctt
      661 aaaaactatc ctccaacaaa tcccctttac attaacagca ttggtgttga tgacgtcggc
      721 tttttgctgg ttactacatc gctcactggc caaaccgtta tggcgttttg tcgatatcat
      781 taataaaacc gcaactgcac cgctgagcac acgtttacca gcacaacgac tggatgaatt
      841 agatagtatt gccggtgctt ttaaccaact acttgatacc ctacaagtcc aatacgacaa
      901 tctggaaaac aaagtcgcag agcgcaccca ggcgctaaat gaagcaaaaa aacgcgctga
      961 gcaagctaac aaacgtaaaa gcattcatct tacggtaata agtcatgagt tacgtactcc
     1021 gatgaatggc gtactcggtg caattgaatt attacaaacc acccctttaa acatagagca
     1081 gcaaggatta gctgataccg ccagaaattg cacactgtct ttgttagcta ttattaataa
     1141 tctgctggat ttttcacgca tcgagtctgg tcatttcaca ttacatatgg aagaaacagc
     1201 gttactgccg ttactggacc aggcaatgca aaccatccag gggccagcac aaagcaaaaa
     1261 actgtcatta cgtacttttg ttggtcaaca tgtccccctc tattttcata ccgacagtat
     1321 ccgtttacgg caaattttgg ttaatttact cgggaacgcg gtaaaattta ccgaaaccgg
     1381 agggatacgt ctgacggtca agcgtcatga ggaacaatta atatttctgg ttagcgatag
     1441 cggtaaaggg attgaaatac agcagcagtc tcaaatcttt actgcttttt atcaagcaga
     1501 cacaaattcg caaggtacag gaattggact gactattgcg tcaagcctgg ctaaaatgat
     1561 gggcggtaat ctgacactaa aaagtgtccc cggggttgga acctgtgtct cgctagtatt
     1621 acccttacaa gaataccaac cgcctcaaca aattaaaggg acactgtcag cgccgttctg
     1681 cctgcatcgc caactggctt gctggggaat acgcggcgaa ccaccccacc agcaaaatgc
     1741 gcttctcaac gctgagcttt tgtatttccc cggaaaactc tacgacctgg cgcaacagtt
     1801 aatattgtgt acaccaaata taccaataat aaataatttg ttaccaccct ggcagttaca
     1861 gattcttttg gttgatgatg ccgatattaa tcgggatatc atcggcaaaa tgcttgtcag
     1921 cctgggccaa cacgtcacta ttgccgccag tagtaacgag gctctgactt tatcacaaca
     1981 gcaacgattc gatttagtac tgattgacat tagaatgcca gaaatagatg gtattgaatg
     2041 tgtacaatta tggcacgatg agccgaataa tttagatcct gactgcatgt ttgtggcgct
     2101 atccgctagc gtagcgacag aagatattca tcgttgtaaa aaaaatggga ttcatcatta
     2161 cattaccaaa ccagtgacgt tggctacctt agctcgctat atcagtattg ccgcagaata
     2221 ccaactttta cgaaatatag agctacagga gcaggatcca agtcgctgct cagcgctact
     2281 ggcgacagat gatatggtca ttaatagcaa gattttccaa tcactggacc tcttgctggc
     2341 tgatattgaa aatgccgtat cggctggaaa aaaaatcgat cagttaattc acacattaaa
     2401 aggctgttta ggtcaaatag ggcagactga attggtatgc tatgtcatag acattgagaa
     2461 tcgcgtaaaa atggggaaaa tcatcgcgct ggaagaacta accgacttac gccaga
//
LOCUS       DAJVBX010000305         2514 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.306, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000305 DAJVBX010000000
VERSION     DAJVBX010000305.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2514
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.306"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            240..992
                     /locus_tag="OPV72_004335"
     CDS             240..992
                     /locus_tag="OPV72_004335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="non-specific acid phosphatase"
                     /protein_id="HCR9916465.1"
                     /translation="MKSRYLLFFLPLIVAKYTSAATMQPFHSPEESVNSQFYLPPPPG
                     NDDPAFRYDKEAYFKGYAIKGSPRWKQAAEDADISVENIARIFSPVVGAKINPKDTPE
                     TWNMLQNLLKMGGYYATASAKKYYMRTRPFVLFNHSTCRPEDENTLRKDGSYPSGHTA
                     YSTLLALVLSQARPERAQELARRGWEFGQSRVICGAHWQSDVDAGRYVGAVEFARLQT
                     IPAFQKSLAKVREELNDKNNLLSKEERPELNY"
     gene            complement(1233..1724)
                     /locus_tag="OPV72_004336"
     CDS             complement(1233..1724)
                     /locus_tag="OPV72_004336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCR9916466.1"
                     /translation="MISTPEPLHAGHILTPFCCGVDSIDNWLKQRAMKNQTTGASRTF
                     VCCGSDSNVLAYYSLASSAVTTNTSPGRFRRNMPDPIPVVVLGRLAVDKSLHGQGVAR
                     ALVRDAGLRVIQVAETIGIRGMLVHALSDEAREFYQWVGFVPSPMDPMMLMVTLGDLV
                     ESV"
     gene            complement(1721..2014)
                     /locus_tag="OPV72_004337"
     CDS             complement(1721..2014)
                     /locus_tag="OPV72_004337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1778 domain-containing protein"
                     /protein_id="HCR9916467.1"
                     /translation="MPAANSMAMKRETLNLRIKPAERDLIDRAAKARGKNRTDFVLEA
                     ARAAAEEVLIEQRIIMADPEAYQEFLVRLDQTPSPNAALRKTMQTPAPWEQEK"
BASE COUNT          687 a          637 c          575 g          615 t
ORIGIN      
        1 aacctaatgc gtgtcagtca ggcacgcaga taaaaaataa ccggggacaa aagttaaaca
       61 aaatgctgtt agccggaagt atcagtattg ttctgttgtc cgctacagtc agtccggtat
      121 ggacagacga taatgccagt gcagcgtcct gcttttttac ctgtatgttg aataaccatt
      181 tcaataaatc attatagaat cacatctgtt tattattgcc tgatccgggg tgagtcttta
      241 tgaaaagtcg ttatttacta ttttttctac cactgatcgt agctaaatat acatcagcag
      301 caacaatgca accctttcat tctcctgaag aatcagtgaa cagtcagttc tacttaccac
      361 caccgccagg taatgatgat ccggctttcc gctatgataa ggaggcttat tttaagggct
      421 atgcgataaa gggttcccca cgatggaaac aagctgctga ggatgcagat ataagcgtgg
      481 aaaatatagc cagaatattc tcgccagtag tgggtgctaa aattaatccc aaagatacgc
      541 cagaaacctg gaatatgtta cagaatcttc tgaaaatggg cggctactac gctactgctt
      601 cggcaaaaaa atattatatg cgtactcgtc cctttgtctt atttaatcat tctacctgcc
      661 gtcctgaaga tgagaatact ttgcgaaaag atggctctta cccttccggg catactgctt
      721 atagtacact tctggcatta gtattatccc aggccagacc ggaacgcgcg caggagctcg
      781 ccagacgagg atgggagttc gggcaaagca gagtgatatg cggtgctcac tggcaaagcg
      841 atgttgatgc tggccgttat gtgggagcag tagagtttgc aaggctgcaa acaatcccgg
      901 cttttcagaa gtcactggca aaagtccgtg aggagctgaa cgacaaaaat aatttattga
      961 gtaaagaaga acgccccgaa cttaattact gaaggtgaaa gtcttcccgc aaactggcca
     1021 cagcaaatga aaggaagtgc aactgcgtag gggcgaccgg gcgtggagaa cgcctttggt
     1081 ttccccgatt cgcatgaatt caacgtcccc gtttgcagtc cgtccagacc gtcatgacgt
     1141 cgttgtccgg ctgaagcggt aaaaccggtc tggctcactg actatccaca gcgaattccg
     1201 gccatcagaa gctaagggat gcgttctgga gtttaaacac tctccaccaa atcccccaac
     1261 gtcaccatca acatcatcgg atccatcggc gacggtacaa accccaccca ctgataaaat
     1321 tcccgcgctt catccgacag ggcgtgaacc agcatcccac gaatgccgat agtctccgcc
     1381 acctgaataa cccgcagccc tgcgtcgcgt accagcgccc gagcgacgcc ctgcccatga
     1441 agcgatttat ccaccgccag acgccccaat accacaaccg gaatcgggtc aggcatattg
     1501 cgacgaaagc gaccggggga ggtattcgtc gtgaccgcgc tggacgccag cgagtaatag
     1561 gccagtacgt tcgaatcgct gccacaacac acaaaggtac gggacgcgcc agtggtctga
     1621 tttttcatcg cccgctgttt cagccagtta tctatagaat ccacaccgca gcaaaacgga
     1681 gtaagaatat gtccggcatg aagcggctca ggggtggaga tcatttttcc tgctcccacg
     1741 gcgcaggggt ctgcatggtt ttacgcagtg cggcattagg tgaaggtgtt tgatccaaac
     1801 gaacgagaaa ttcctgataa gcctctggat cggccataat gatgcgttgt tcgataagca
     1861 cttcttctgc ggcagcacgg gcagcttcca acacaaagtc tgtgcggttt ttccctctgg
     1921 ctttcgccgc tcgatcaata agatcgcgct cggcgggttt gatacgcagg ttcagagttt
     1981 cacgtttcat cgccatactg tttgcggctg gcatagtgtt gtcctcttgt acttctgtgg
     2041 atattaagta tacaacacgc gtaacgcaga tgtcattacg ataaatttag aaggaatgga
     2101 accggagtag cgaaccgaaa ggttttctac tcatttatag attcagtacc aggctgtgcg
     2161 ctggcattcg ctgtgagtga ttcctcctcg gggccgacgc agcaaaagat tcaatactgc
     2221 cgcgccaaaa cacgcaacat tatataatca gaaagcataa acctaacgga tacgcacagt
     2281 aagaacctca ataacgtgtt acatcgtttt tcataaagcc aaccatacga ttgaatgttt
     2341 cccctccccc tcaaacttcc ggatattgtt acaccgtcta cccgccgcag tatatattta
     2401 ccgcgttgta tgcctttcct ggccgagatc gttaatattt acctccaaga taaaccttat
     2461 cacaaattaa catcagatct tatacctcat gctaactacc cccatgaaat taaa
//
LOCUS       DAJVBX010000306         2508 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.307, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000306 DAJVBX010000000
VERSION     DAJVBX010000306.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2508
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.307"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            60..323
                     /gene="pagD"
                     /locus_tag="OPV72_004338"
     CDS             60..323
                     /gene="pagD"
                     /locus_tag="OPV72_004338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence protein PagD"
                     /protein_id="HCR9916468.1"
                     /translation="MKHHAFMLWSLLIFSFHVLASSDHCSGLQQASWEIFIYDFGSKT
                     PQPPTNTDKKQARQISSPSCPTAKPMMSAPTNDARKGNTFSRT"
     gene            455..667
                     /gene="cspF"
                     /locus_tag="OPV72_004339"
     CDS             455..667
                     /gene="cspF"
                     /locus_tag="OPV72_004339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock-like protein CspF"
                     /protein_id="HCR9916469.1"
                     /translation="MSRKMTGIVKTFDCKSGKGLITPSDGRKDVQVHISACRQHETEA
                     LIPGIRVEFCRINGLRGPTAANVYLS"
     gene            1085..1606
                     /locus_tag="OPV72_004340"
     CDS             1085..1606
                     /locus_tag="OPV72_004340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ricin-type beta-trefoil lectin domain protein"
                     /protein_id="HCR9916470.1"
                     /translation="MTLLSGKNTLVLCLSSILCGCTTNGLPAPYSINLSFPVITQNQI
                     NSGGYYINDAEQIRTTDGLCLDTGPDQQNRLTLRECKHVQSQLFSFHRDRITQGEKCL
                     DAAGQGTKEGTPIILYSCTGNDNQRWLTDDNKIKGKQSRKCLGTNSIIVRKGDPVVLA
                     DCDFSRALEFTIR"
     gene            1797..2036
                     /gene="msgA"
                     /locus_tag="OPV72_004341"
     CDS             1797..2036
                     /gene="msgA"
                     /locus_tag="OPV72_004341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence protein MsgA"
                     /protein_id="HCR9916471.1"
                     /translation="MFVELVYDKRNVEGLPSAREIILNELTKRVHQLFPDAQVKVKPM
                     QANALNSDCTKTEKERLHRMLEEMFEEADMWLVAE"
BASE COUNT          705 a          567 c          533 g          703 t
ORIGIN      
        1 tgacgtccca taattaatta gatgaacttc gcaagtcatt acatataaca ggaggtgcta
       61 tgaaacatca tgcttttatg ctttggtcat tacttatttt ttcattccat gttttggcca
      121 gttcagacca ttgttctggt ttacaacagg catcatggga aatttttatc tacgattttg
      181 gtagtaaaac cccgcaacca cctacaaata ccgataaaaa gcaagccagg cagattagtt
      241 caccatcctg cccgacggca aaacccatga tgtccgcacc aaccaacgac gccaggaaag
      301 ggaatacttt ctccagaaca taatgttatt tatctacaat ggtgccgaac gactactttt
      361 agccatccgg aaatcttgat tgccatcaaa tatagctggc attatttttc ctgacgtgta
      421 tagtgcgcct cgttatcccc attaaggaat ttgtttgtct cgtaaaatga caggaattgt
      481 caaaaccttt gattgtaaga gcggtaaagg tctcatcacc ccctccgatg gacgcaaaga
      541 tgttcaggtc cacatttcag catgtcgcca acacgaaaca gaagctctta tccccggtat
      601 acgcgttgag ttttgtcgta ttaatggact ccgcggacct accgccgcca acgtttatct
      661 ttcataattc gtcacccggc attttttcag aaaaatttag cgagtacgta tacctccgca
      721 gtctgctatg aggctttgcc tgaaaggctg cagaatgttt tcagtggcga aaatctaaaa
      781 gatttatttt gctaatgact cctgtgacct cttttatcat atatcgggtg tcaacccccc
      841 ttctcacttt gtttaacgtg aagaaatgta cagccgtttt tcactgtgat agcatgtaat
      901 attgcaaaag tatttaacgc tatataccca tcgtcgcagg agtggctggc tgcgcgcatt
      961 taaccgaagt atttatgtga ttctatcgga attatcttta ttgccgctca atgctacgtc
     1021 atattcagtg ggtataaatt gccaatatag ttgtaatgct atttattttt agggtaataa
     1081 ttgaatgact ttgctttcag gaaaaaacac actggttctc tgcctctcct ctattttatg
     1141 tggatgtacg acgaacggct tacccgcacc ttatagtatt aatttgtcgt tcccggtcat
     1201 tacacaaaac caaattaatt ccggtggtta ttacataaat gacgcggaac aaattcggac
     1261 aactgatggt ctgtgccttg atacaggccc agatcaacag aatcgtttga cgctgcggga
     1321 gtgtaaacat gtgcaatctc agcttttctc atttcaccga gacagaatca cgcagggtga
     1381 gaaatgtctg gatgctgcag gacagggtac gaaagaaggc acgccaatca ttctttattc
     1441 atgcacgggt aatgataacc agcgctggct cactgatgat aacaaaatta aggggaaaca
     1501 gagccgaaaa tgcctgggca caaatagcat tattgtcaga aaaggcgacc ctgttgtgtt
     1561 agccgattgc gattttagtc gcgccctgga atttaccatc aggtagcagg acaccgctgt
     1621 gaagagagag ccgctaacct cttgacatga caacaggtta gcgaccttta cttccatgtg
     1681 cgatcaattt actttacatc cgcaacgtta ggatgacaaa acggcggcta aaccttgaca
     1741 ccggttatat acccagctta aatactggtc atccaaccag taaaaaggaa atggcgatgt
     1801 tcgtcgaact cgtttatgac aagcgaaatg ttgaaggttt gccaagcgca cgcgaaatca
     1861 tcctcaatga actcacaaaa cgcgtacatc aactttttcc cgatgcgcaa gtgaaagtta
     1921 agccaatgca ggcgaacgca ttaaacagtg actgtacaaa aaccgagaaa gaacggctgc
     1981 accgtatgct ggaagagatg tttgaagagg ctgatatgtg gctggtcgcc gaataacgtc
     2041 ccctcctgcg aaagcgacat gtccgatcga aaacagcgcc ctgaggcgct gtctgtgacg
     2101 atataacgca aacgccacca ctcagaacat gtagcggaag ttggcgttta tagcgtggtc
     2161 aacatgctat ttgccaaatg ccgccagctc cagtcattgt cactgaacgt tttgcccagt
     2221 gccacacctg tacgccctat caacggatta tacgttttgt tgcgcatcga cgctattggt
     2281 cacggtttta cagtaaaaac ggtacctgtt ctcagactct tccggcgtca gtgcaccgtt
     2341 ataatgatga ggtctgacgc tattgtagcc gttcaagatg taaccattga tttgtttggt
     2401 tttcttgttc actaagttac ctgttttgtg ttgaggtgag aacatcgcct ttaatcaggt
     2461 ggccaaattt actatgtcac tacaagagtg agaatagatg aaatgtca
//
LOCUS       DAJVBX010000307         2492 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.308, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000307 DAJVBX010000000
VERSION     DAJVBX010000307.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2492
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.308"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..577
                     /locus_tag="OPV72_004342"
     CDS             <1..577
                     /locus_tag="OPV72_004342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCR9916472.1"
                     /translation="QPAQNGFRSDLLLLSPEIIARFKTMYVQDYPPANLTSLCTPMSR
                     SLTFMWENVLDAVRQGLPVGLQEHQAMGLLLALLHDGAAGPLLIERRYTLTEQVRQLI
                     MLSPAKLWTAQEIARRLAMGTSTLRRRLQRESQSYRQIIEEVRMSCALSQLQSTTLPI
                     GEIALRCGYLSGSRFTARFRQHYGCLPSQVR"
     gene            626..907
                     /gene="yccX"
                     /locus_tag="OPV72_004343"
     CDS             626..907
                     /gene="yccX"
                     /locus_tag="OPV72_004343"
                     /EC_number="3.6.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HCR9916473.1"
                     /translation="MSNVCIIAWVYGRVQGVGFRYTTQHEAQRLGLTGYAKNMDDGSV
                     EVVACGDAAQVEKLIKWLKEGGPRSARVDKILTEPHSPRETLTGFSIRY"
     gene            complement(904..1233)
                     /gene="tusE"
                     /locus_tag="OPV72_004344"
     CDS             complement(904..1233)
                     /gene="tusE"
                     /locus_tag="OPV72_004344"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase TusE"
                     /protein_id="HCR9916474.1"
                     /translation="MLIFEGKEISTDSEGYLKETTQWSEALAVAIAANEGIELSAEHW
                     EVVRFVREFYLEFNTSPAIRMLVKAMANKFGEEKGNSRYLYRLFPKGPAKQATKIAGL
                     PKPVKCI"
     gene            complement(1320..1979)
                     /gene="yccA"
                     /locus_tag="OPV72_004345"
     CDS             complement(1320..1979)
                     /gene="yccA"
                     /locus_tag="OPV72_004345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000375124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsH protease modulator YccA"
                     /protein_id="HCR9916475.1"
                     /translation="MDRIITSSRDRSSLLSTHKVLRNTYFLLSLTLAFSAITATASTV
                     LMLPSPGLILTLVGMYGLMFLTYKTANKPVGILSAFAFTGFLGYILGPILNAYLSAGM
                     GDVIGLALGGTALVFFCCSAYVLTTRKDMSFLGGMLMAGIVVVLIGMVANIFLQLPAL
                     HLAISAVFILISSGAILYETSNIIHGGETNYIRATVSLYVSLYNIFVSLLSILGFASR
                     D"
     gene            2374..2461
                     /locus_tag="OPV72_004346"
     tRNA            2374..2461
                     /locus_tag="OPV72_004346"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2408..2410,aa:Ser,seq:tga)
BASE COUNT          632 a          618 c          671 g          571 t
ORIGIN      
        1 tcagcctgcg cagaacggtt ttcgctccga cctgttgtta ctttcaccgg agattattgc
       61 tcgctttaaa acgatgtatg ttcaggatta tccaccggca aacctgacat cgctgtgtac
      121 gccgatgagc cgtagcctga catttatgtg ggagaacgtg ttggatgctg tgcgccaggg
      181 gttgcccgtt gggctacagg aacatcaggc gatggggtta ctgttagcgc ttttacatga
      241 tggcgcggcg ggaccgctgc ttattgaacg gcgttacacc ctcacggagc aggtgcggca
      301 actgattatg ctctcacctg ctaagctatg gacagcccag gagatagccc gccgccttgc
      361 tatgggaaca tcgacgctgc gtcggcgttt gcagcgcgaa tcgcagagtt atcggcaaat
      421 tattgaagag gtacgcatgt cctgcgcgct ttctcaactg caatcgacga cgctgccgat
      481 cggcgaaata gcgctacggt gcggctacct gtcggggtcg cgatttacgg ccagattccg
      541 ccaacattat gggtgtctgc ccagtcaggt acgttaagta tgtcctgtat gcgtcttcac
      601 cgttgattat gaaaggagaa ccatcatgtc gaacgtctgc attatcgcct gggtttatgg
      661 tcgcgttcag ggcgtcgggt ttcgctatac cacgcagcat gaggcgcagc ggctggggtt
      721 aaccggctat gcgaagaata tggatgacgg aagcgtagaa gtggtggcct gtggcgacgc
      781 ggcgcaggta gaaaagctca tcaagtggct gaaagaaggc ggaccgcgct ctgctcgtgt
      841 ggacaaaatc ctcactgaac cgcacagccc tcgcgagacg ctaacaggat ttagtattcg
      901 gtattaaata cattttaccg gcttgggcag accggcgatt ttggtcgctt gctttgccgg
      961 gcctttcggg aacagacgat acagatagcg gctgttgcct ttttcttcgc cgaacttatt
     1021 cgccatcgct tttaccagca ttcggatggc gggagaggta ttaaactcca ggtaaaattc
     1081 gcgcacgaag cgcacgactt cccagtgttc cgcagagagc tcaatgcctt cattggcggc
     1141 gatagcgact gccagcgctt cactccactg cgtcgtctct ttcagatagc cttcgctatc
     1201 agtactgatt tctttacctt caaagatcaa cataacgttt cactgcgtaa tcaacacgga
     1261 cggcagtgta gcaaaaaata aagccctgca taagcagggc tggaagaggg gaatgtcgat
     1321 tagtcgcggc tggcgaagcc cagaatgctg agcaggctga caaagatgtt gtacagcgaa
     1381 acgtacagac tgacggtcgc acgaatatag ttggtttcac cgccgtgaat gatgttactg
     1441 gtttcataca ggatagcgcc cgaggaaatc aggataaaca ccgcgctaat cgccaggtgc
     1501 aatgcaggca gttgcaggaa aatattcgcc accataccaa tcagcacgac gacgatcccg
     1561 gccattagca taccgcccag gaaagacata tccttacggg tggtcagaac gtaagcggag
     1621 cagcagaaaa atactaacgc ggtaccaccc agcgccaggc caatcacatc gcccatgcct
     1681 gctgacagat aggcgttaag aatcgggccc aggatatagc cgaggaagcc ggtaaacgca
     1741 aaagcagaca ggataccgac cggcttattg gcggttttat aggtcaggaa catcagccca
     1801 tacataccga ccagcgtcag aatcaggccg ggggagggca gcatcagtac cgtactggct
     1861 gtcgcggtaa ttgcggagaa agccagcgtc aggctcaaca gaaaataggt gttgcgcagt
     1921 actttgtgcg tactcagtag cgagctacga tcacgcgatg atgtaatgat acgatccatt
     1981 agtcactctc ttatgacaga tgtaattaat aaaggagaat aataaaaaca gtcactgtca
     2041 cccagtggtt ttacccatct ttacgcattc gtttacgttt agtttcctta agagatttca
     2101 ggtgattacc gtcgttaaaa cggtctgctc atgcctggcg ctacgccata aaacaggcgg
     2161 cagcgccaac cacgcgttac cgataaaaaa ttgataatca cagaggtaaa acagtgggga
     2221 cgatcaacac gtattcagcc cgtttttgtg ttgaagaaat ggtcaatgtg ccgctatttc
     2281 aggcaattaa cgaaaatttg cctgtttttc acgcaaacga acacattcgg tctttacatg
     2341 acgcaccggg atgtttatag tgcgcctcat tctggaagtg tggccgagcg gttgaaggca
     2401 ccggtcttga aaaccggcga cccgaaaggg ttccagagtt cgaatctctg cgcttccgcc
     2461 agattaaaca aggggttacc gaaaggtaac cc
//
LOCUS       DAJVBX010000308         2479 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.309, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000308 DAJVBX010000000
VERSION     DAJVBX010000308.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2479)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2479)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2479
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.309"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            21..1034
                     /locus_tag="OPV72_004347"
     CDS             21..1034
                     /locus_tag="OPV72_004347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCR9916476.1"
                     /translation="METNITWQQLIDEYFFAKPLRSASEWSYTKVFKSFVHYMGPLSC
                     PNDVTYHKVLAWRRFLLKEKKLSGRTWNNKVAHMRAIFNYGIQRGLLHYDENPFNNSV
                     VKPDKKRKKTLTQAQIEYAYQIMEQYENQENTGLGLKYSRCALFPAWFWLTVLDTLYY
                     TGIRQNQLLHIRLNDVDLREGQIRLITEGCKNHKEHYVPVISFLRPRLTCLMEKAQSE
                     GLKGNDRLFNIALFTGKDPAIGDDMDSPQVRAFFRRLSKECQFAISPHRFRHTLATEM
                     MKMPEQNLHMAQSVLGHSNMKSTLEYVENDIAVMGRALEAQFMQIKAAHARSIYSGLT
                     KNR"
     gene            1461..1754
                     /locus_tag="OPV72_004348"
     CDS             1461..1754
                     /locus_tag="OPV72_004348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1778 domain-containing protein"
                     /protein_id="HCR9916477.1"
                     /translation="MPVANSMAMKRETLNLRIKPAERDLIDRAAKARGKNCTDFVLEA
                     ARAAAEEALIEQRIIMADPEAYQAFLIRLDQAPAPNDALRKTMQTPAPWEQEK"
     gene            1751..2239
                     /locus_tag="OPV72_004349"
     CDS             1751..2239
                     /locus_tag="OPV72_004349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004889762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCR9916478.1"
                     /translation="MISAPEPLHAGHILTPFCCGVDSMDNWLKQRAMKNQVTGASRTF
                     VCCGSDSDVLAYYSLASSAVTTNTAPGRFRRNMPDPIPVVVLGRLAVDRSLHGQGVGR
                     ALVRDAGLRVIQVAETIGIRGMLVHALSDEAREFYLRVGFEPSPMDPMMLMVTLGDLV
                     HA"
BASE COUNT          669 a          545 c          638 g          627 t
ORIGIN      
        1 gctcaatagc ggtgataaaa atggaaacaa atattacctg gcaacaattg atagatgaat
       61 atttcttcgc aaaacctctg cgctcagcat ctgaatggag ttacaccaaa gtcttcaaat
      121 catttgtaca ttatatgggg ccgttaagct gccctaatga tgtgacatat cacaaagtgc
      181 ttgcctggcg ccgttttctt ttaaaagaga aaaagctgtc cggacgtacc tggaataaca
      241 aggtggcgca tatgcgggcc atctttaact acggaataca gcgagggtta ctgcactatg
      301 acgaaaatcc gtttaacaat tcggtagtta aaccggacaa gaagagaaag aaaacgctca
      361 ctcaggcaca gattgagtat gcctatcaga tcatggagca gtatgaaaat caggagaata
      421 cagggctggg actgaaatat tcccgctgcg ccttatttcc tgcatggttc tggctcactg
      481 tcctggatac gctctattac acagggatac gtcagaacca gttattacat attcggctga
      541 atgatgttga tttgagagaa gggcagattc ggctgattac ggaggggtgt aaaaatcaca
      601 aagaacacta tgtgccggtg atcagttttc tgcgtccacg gctgacctgt ttaatggaga
      661 aagcgcagag cgaaggattg aaaggtaatg accgcctgtt caatattgca ctttttaccg
      721 gcaaagatcc cgccattggc gatgacatgg attctcctca ggtaagagca ttcttccgtc
      781 gtctgtccaa ggagtgtcag tttgcgatca gtcctcatcg tttcagacac acgctggcca
      841 cggagatgat gaaaatgccg gaacagaatc tgcatatggc gcaaagtgtg ctgggtcatt
      901 caaacatgaa atccacgctg gagtatgtgg agaatgatat tgcagtgatg gggagggctc
      961 tggaagcgca gtttatgcag attaaggcag cacatgcccg aagcatttac agtgggttga
     1021 caaagaatag ataagctgta acgatatcgg gtgatcgaga aaagggaact tgcgccaaca
     1081 agttccctta cttgagaaac ccaaaaatcc atctcgatgt gtagactgac ctgctacatc
     1141 gattgtcctt tcgggttcca cgtaacgtcc gttaaggttc tcaagcccta accaacgtac
     1201 tttgataaga gtggtgcccg gactcgggag cattcagcta tctattaaat tgaattccgt
     1261 cataaatccg tttttgacga attgtcaaga ccctgagcgt gacccgtatt tttacttgta
     1321 aatcaaaata gtggcttttg aggtataaaa acttgttcgg ttcgatgcac tggttcgatt
     1381 ccctttaaat ctatcgtaat gacatctgcg ttacgcgtgt tgtatactta atatccacag
     1441 aaacacaaga ggacaacacc atgccagtcg caaacagtat ggcgatgaaa cgcgaaaccc
     1501 tgaacctgcg catcaagccc gccgagcgcg atcttatcga tcgggctgca aaagccagag
     1561 ggaaaaactg cacagacttt gtgctagaag ctgcccgcgc cgccgccgag gaagcgctga
     1621 tcgagcaacg catcattatg gccgatccag aggcttatca ggcatttctg atccgtctgg
     1681 atcaggctcc tgcgccaaac gatgcgttgc gtaaaaccat gcagactcct gcaccgtggg
     1741 agcaggaaaa atgatctccg cccctgaacc gcttcatgcc gggcatattc ttaccccctt
     1801 ctgctgcggt gtggattcaa tggataactg gctaaaacag cgggcgatga aaaatcaggt
     1861 aactggcgca tcccgtacct ttgtgtgttg cggcagcgat tctgacgtac tggcgtatta
     1921 ttcgctggcg tccagcgcgg taacgacaaa caccgccccc ggtcgctttc gtcgcaatat
     1981 gcccgatccg atcccggttg tggtgctggg ccgtctggcg gtggatcggt cgctacatgg
     2041 gcagggcgta ggtcgggcgc tggtgaggga tgccgggctg cgggtgattc aggtggcgga
     2101 aactatcggt attcgcggga tgctggtcca tgccctgtcg gatgaagcgc gggagtttta
     2161 cctgcgggtg gggtttgagc cgtcgccgat ggatccgatg atgttgatgg tgacgttggg
     2221 ggatttggtt catgcctgat tggtattatt tggtgccaat aagatggttg ttttatgaat
     2281 caaattatca atgatatatt gttgctcggc atgtccgctg tctgaagtca tcaggtatct
     2341 tcagtgttta atgtgaagta aaataagatc tgcgcacaac ctcaaacatt attttaatgc
     2401 ttgaggtttg attacaattc aaaagttaaa aattaacttc atccggggaa aaagattaga
     2461 aaaaaagacc aagaaacta
//
LOCUS       DAJVBX010000309         2463 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.310, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000309 DAJVBX010000000
VERSION     DAJVBX010000309.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2463
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.310"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..1059)
                     /gene="ssaD"
                     /locus_tag="OPV72_004350"
     CDS             complement(<1..1059)
                     /gene="ssaD"
                     /locus_tag="OPV72_004350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SctD family type III secretion system inner
                     membrane ring subunit SsaD"
                     /protein_id="HCR9916479.1"
                     /translation="MAYLMVNPKSSWKIRFLGHVLQGREVWLNEGNLSLGEKGCDICI
                     PLAINEKIILREQADSLFVDAGKARVRVNGRRFNPNKPLPSSGVLQVAGVAIAFGKQD
                     CELADYQIPVSRSGYWWLAGVFLIFIGGMGVLLSISGQPETVNDLPLRVKFLLDKSNI
                     HYVRAQWKEDGSLQLSGYCSSSEQMQKVRATLESWGVMYRDGVICDDLLIREVQDVLI
                     KMGYPHAEVSSEGPGSVLIHDDIQMDQQWRKVQPLLADIPGLLHWQISHSHQSQGDDI
                     ISAIIENGLVGLVNVTPMRRSFVISGVLDESHQRILQETLAALKKKDPALSLIYQDIA
                     PSHDESKYLPAPVAGFVQS"
     gene            complement(1040..>2463)
                     /gene="spiA"
                     /locus_tag="OPV72_004351"
     CDS             complement(1040..>2463)
                     /gene="spiA"
                     /locus_tag="OPV72_004351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="SPI-2 type III secretion system protein SpiA"
                     /protein_id="HCR9916480.1"
                     /translation="WKGNDFTLYARQMPLAEVLHLLSENYDTAITISPLITATFSGKI
                     PPGPPVDILNNLAAQYDLLTWFDGSMLYVYPASLLKHQVITFNILSTGRFIHYLRSQN
                     ILSSPGCEVKEITGTRAVEVSGVPSCLTRISQLASVLDNALIKRKDSAVSVSIYTLKY
                     ATAMDTQYQYRDQSVVVPGVVSVLREMSKTSVPASSTTNGSPATQALPMFAADPRQNA
                     VIVRDYAANMAGYRKLITELDQRQQMIEISVKIIDVNAGDINQLGIDWGTAVSLGGKK
                     IAFNTGLNDGGASGFSTVISDTSNFMVRLNALEKSSQAYVLSQPSVVTLNNIQAVLDK
                     NITFYTKLQGEKVAKLESITTGSLLRVTPRLLNDNGTQKIMLNLNIQDGQQSDTQSET
                     DPLPEVQNSEIASQATLLAGQSLLLGGFKQGKQIHSQNKIPLLGDIPVVGHLFRNDTT
                     QVHSVIRLFLIKASVVNNGISHG"
BASE COUNT          695 a          603 c          472 g          693 t
ORIGIN      
        1 actctgtaca aagccagcca ctggcgcagg cagatacttg ctttcatcat gagaaggcgc
       61 aatatcctga taaattaaag aaagagcggg gtcctttttc tttaatgctg ctaacgtttc
      121 ttgcaaaatg cgttgatgag attcatccag tacaccactg ataacaaaag agcgccgcat
      181 tggcgtaaca ttgacaagcc ccactaaacc gttctctatt atcgcagaaa taatatcatc
      241 cccctgagac tgatgagaat gactaatctg ccagtgcaat aacccgggaa tatctgcaag
      301 taatggttga accttacgcc attgctgatc catttgtata tcatcatgaa ttaacacgct
      361 ccccggccct tcgctggata cttcagcatg cgggtaaccc atttttatca aaacatcctg
      421 cacttctcgt atcaataagt catcacagat tacaccatcc cgatacatga ccccccatga
      481 ttcgagagtc gctctcacct tttgcatctg ttcgcttgac gagcaataac cggacaactg
      541 caggcttcca tcttctttcc attgcgcccg cacataatga atattgcttt tgtctaataa
      601 aaacttaacc cgcaaaggta agtcatttac cgtttcaggc tgaccactaa tacttaacag
      661 gacacccatt ccaccgatga aaatcaagaa tacgccagcc aaccaccagt accctgatct
      721 ggaaacgggt atttgataat cagcaagttc acaatcctgt ttaccaaacg cgatagccac
      781 tcccgcaacc tgcaaaaccc cactggatgg tagcggctta tttggattaa atctgcggcc
      841 attaactcta actctggctt tcccggcatc aacaaataaa ctatctgcct gttctctcag
      901 aataattttt tcatttatag ccagcggaat acaaatatcg catcccttct cccccagtga
      961 caggttacct tcattcagcc atacttcccg gccttgtaaa acgtgaccta aaaaacgtat
     1021 tttccaggaa ctctttggat taaccatgag atatgccatt atttactact gaggctttaa
     1081 tcaaaaaaag cctgattaca ctatgtactt gagtcgtatc attgcgaaac aaatgaccta
     1141 cgacagggat atcgcccaat aaagggattt tgttttgcga gtggatttgt ttaccttgtt
     1201 taaaccctcc cagcaataga ctttgtccgg ccaataatgt ggcttgcgaa gcaatttcag
     1261 aattttgcac ttcgggtagc ggatctgttt cgctttgcgt atcactttgt tgtccatcct
     1321 gaatattaag attaagcatt attttttgcg tgccattgtc atttaacaag cgaggtgtaa
     1381 cgcgcaacaa agaacccgta gtgatggatt caagtttagc cactttttct ccctgcagtt
     1441 tggtatagaa agtaatattt ttatccagca cagcctggat attatttaaa gtcaccacag
     1501 atggctggga aagtacataa gcctgagagc ttttttccag ggcattcaaa cgcaccataa
     1561 agtttgaggt atcgctgatt accgttgaaa aaccgctagc accaccgtca ttcaaacctg
     1621 tattgaacgc aattttcttg ccacccagcg acactgccgt tccccagtcg atgcctaact
     1681 ggttaatatc tccagcatta acatcgataa ttttcaccga aatctctatc atctgctggc
     1741 gttgatctaa ttctgtgatg agtttccgat acccggccat attggccgca taatcacgaa
     1801 cgatcactgc attctggcgt gggtcggcag caaacatggg caatgcctgt gtagcgggtg
     1861 aaccattggt cgtcgatgac gccggtacgc tggttttact catctcacgc aatacactca
     1921 cgacccctgg aaccacgacg gactgatcgc gatattggta ttgggtatcc atcgcagtgg
     1981 catacttaag cgtgtatata cttacactca ccgcactgtc ttttcgtttg attaacgcat
     2041 tatccagcac tgaagctaat tgactaatac gagtcagaca gctgggaaca ccactcacct
     2101 ccacagctct ggtaccggta atttctttaa cctcgcatcc cggtgatgaa aggatattct
     2161 ggctgcgtaa gtaatgaatg aaccgtccag tagataaaat attgaaagtg ataacctgat
     2221 gttttaataa cgatgcagga tatacatata acatgctgcc atcaaaccag gttagcaaat
     2281 catattgtgc tgccaggtta ttcaaaatat cgaccggtgg tccaggcgga atttttccac
     2341 taaatgtagc tgttatcaat gggctaatag taatagccgt atcatagttc tctgagagca
     2401 gatgtaaaac ctctgctaat ggcatttgtc tggcataaag ggtgaagtca ttacctttcc
     2461 atg
//
LOCUS       DAJVBX010000310         2409 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.311, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000310 DAJVBX010000000
VERSION     DAJVBX010000310.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2409)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2409)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2409
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.311"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..284)
                     /locus_tag="OPV72_004352"
     CDS             complement(<1..284)
                     /locus_tag="OPV72_004352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916481.1"
                     /translation="MRMSKHNLIIYSLLLAAVPISVLADSSTTSAATVGMFSPPTAPS
                     VGHRPGTPRDTYELKFNGLDFSIEKYTPFPGMTIARDDRYLGISDPDNNY"
     gene            complement(305..2287)
                     /locus_tag="OPV72_004353"
     CDS             complement(305..2287)
                     /locus_tag="OPV72_004353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-partner secretion translocator ZirT"
                     /protein_id="HCR9916482.1"
                     /translation="MVFSKKPITKYITWAIVTSQIPLPVIADSDNEIQSWIAGTASSI
                     SPHLQEGTLEDYAKGKIKALPGQAANHLVNEGMKSAFPEIIFRGGVNLEDGAKYRSSE
                     FDMFIPVQETTSSLLFGQLGFRDHDSSSFDGRTYVNVGVGYRQEVNGWLLGVNTFLDA
                     DIRYSHLRGGIGGEVYKDSLAFSGNYYFPLTGWKTSVVHELHDERPAYGFDLRTKGTL
                     PDFPWFSGELTYEQYYGDKVDLLGNGTLSRNPRAAGAALVWNPVPLLEVRAGYRDAGN
                     GGSQAEGGLRVNYSFGTPLHEQLDYRNVGAPSNTTNRRAFVDRNYDIVMAYREQASKI
                     RIMAMPVSGLSGTLVILMATVDSRYPIEKVEWSGDAELLAGLQLQGSLGSGLILPQLP
                     LTATDGQEYSLYLTVTDSRGTRVTSERIPVRVTQDETSFRSWINVINDDVQVEDGNFV
                     ISTPLPAGEEGKVIEWHYVRERSEEEWASLKPRHIKYQSDTPGLAFKALGGTERDGHW
                     VERVLVTHIGDDARSLKLHIEASGPDDKHPVKGTVLLQAQSDSIAQKVTSVEVLFTQG
                     TEEANGSVTAPVVGTEMRARTLCVNNTDCTDAFNYQWEISDEMKSWQSVPGATKATWL
                     LPYSLNGESLQNKYIRVRIISDKGNAKGNTATSDAN"
BASE COUNT          598 a          656 c          551 g          604 t
ORIGIN      
        1 tgatagttat tatccggatc gctgatgcct agatatctat catccctcgc aatagtcatt
       61 cccggaaaag gtgtatactt ttcaatagaa aagtcaagtc cattaaactt caattcgtag
      121 gtatcacgag gtgttcctgg tctgtgccca acgctcggcg ccgtaggagg agaaaacatc
      181 ccgacggttg ccgcggaagt tgtcgacgaa tccgccaaga cgcttatcgg cacagccgcc
      241 agaagcaggc tatagataat aagattatgt ttcgacatac gcactgttga tcctttttaa
      301 aacattaatt cgcatcagag gttgcggtat tacccttagc atttccctta tcagaaataa
      361 ttctgacgcg gatatattta ttctgaagcg attccccatt aagactataa ggaagaagcc
      421 aggtggcctt tgtcgccccc ggtacggatt gccaggattt catttcatcc gagatttccc
      481 actgataatt aaacgcatca gtacagtccg tgttatttac acaaagcgtt ctggctcgca
      541 tttctgttcc gacgactggc gcagtaacgc ttccgttggc ttcttcagta ccctgcgtaa
      601 aaagcacctc cacagaagtg accttctgcg caatactgtc tgactgcgct tgtagtagta
      661 cggtaccctt caccggatgt ttatcgtctg gtccgcttgc ttcaatatgt aatttgagcg
      721 agcgggcatc atcgccgata tgggtcacca gaacccgttc aacccaatgg ccgtcacgct
      781 ctgtaccacc gagcgcttta aatgccagac ccggcgtatc tgattgatac ttaatatgac
      841 gtggtttgag cgacgcccac tcctcttcag aacgctcgcg cacgtagtgc cactcaataa
      901 ccttcccctc ttctccggca ggaagcggcg tactgataac aaagttgccg tcctcaacct
      961 gaacatcgtc attgataaca tttatccagg aacggaaact ggtctcatcc tgtgtcaccc
     1021 ttaccgggat acgctcggag gtcacgcgag taccccggct gtcagtcacc gttaaataaa
     1081 ggctatactc ctgaccgtcg gtcgccgtca gcggaagttg aggaaggata aggccgctgc
     1141 ccaaactccc ctgaagctga agtccggcga gaagttccgc atcacccgac cactcaactt
     1201 tctcaatcgg gtaacggcta tctaccgtcg ccattaatat caccagcgtc ccggacaggc
     1261 ctgacaccgg cattgccata atgcggattt tactggcctg ctcccgatac gccatgacga
     1321 tatcgtaatt acgatcgaca aaggcacgcc gattagtcgt attcgacggc gccccaacgt
     1381 tgcggtaatc aagctgttca tgtaacggcg taccgaagga atagttgact ctcagaccgc
     1441 cctctgcctg cgatccgccg ttaccggcgt cccgatatcc tgctctgacc tcaagcaagg
     1501 ggacaggatt ccagaccaga gccgcacctg cggcgcgggg attccggctt aatgtaccgt
     1561 tacccaatag atcaacttta tccccgtaat actgttcata tgtcagctcg ccactgaacc
     1621 agggaaaatc gggaagcgtg ccttttgttc gcagatcaaa gccatatgcc ggacgctcat
     1681 catgtaattc atgaactact gacgttttcc agccggtgag agggaaataa tagttgccgg
     1741 aaaaggccag actgtcttta tagacttccc cgccaatgcc gccacgcaag tgggaataac
     1801 ggatgtcggc atccagaaac gtattgacgc cgagcagcca tccattgacc tcctggcgat
     1861 aacccacacc aacgttaaca taggtgcggc catcgaaact gctgctgtcg tggtcgcgaa
     1921 agccaagctg gccaaagagt aaagacgatg ttgtttcctg gacgggaata aacatatcga
     1981 actctgatga gcgatatttc gcgccatctt caagattgac gccaccacgg aaaataatct
     2041 ccggaaaagc gctcttcatc ccctcgttca ccagatgatt agcggcttgc cctggtaatg
     2101 cctttatttt tcctttggca taatcctcca gcgtcccctc ctgcagatgc ggagaaatag
     2161 acgatgccgt ccctgcaatc catgactgaa tttcattatc gctatcagcg atgaccggca
     2221 gtggaatctg actggtaaca atggcccagg ttatatattt agtaatgggt tttttagaaa
     2281 aaaccacttt attgtctcct gctatatccc cctgcctggc agagggagta tttaaataag
     2341 atgtttattt ggcgataacc atcagcgacg gatagcgcgt ttattctccg gcgtggcttt
     2401 cgtcgtttt
//
LOCUS       DAJVBX010000311         2382 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.312, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000311 DAJVBX010000000
VERSION     DAJVBX010000311.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2382)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2382)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2382
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.312"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..499
                     /gene="rfbN"
                     /locus_tag="OPV72_004354"
     CDS             <1..499
                     /gene="rfbN"
                     /locus_tag="OPV72_004354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="O antigen biosynthesis rhamnosyltransferase
                     RfbN"
                     /protein_id="HCR9916483.1"
                     /translation="FGIKTVFMSNSFAAYRRSVFEELSGFPEHTILAEDMFMAAKMIQ
                     AGYKVAYCAEAVVRHSHNYTPREEFQRYFDTGVFHACSPWIQRDFGGAGGEGFRFVKS
                     EIQFLLKNAPFWIPRALLTTFAKFLGYKLGKHWQSLPLSTCRYFSMYKSYWNNIQYSS
                     SKEIK"
     gene            500..1939
                     /locus_tag="OPV72_004355"
     CDS             500..1939
                     /locus_tag="OPV72_004355"
                     /EC_number="2.7.7.13"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate
                     guanylyltransferase/mannose-6-phosphate isomerase"
                     /protein_id="HCR9916484.1"
                     /translation="MSFLPVIMAGGTGSRLWPLSREYHPKQFLSVEGKLSMLQNTIKR
                     LASLSTEEPVVICNDRHRFLVAEQLREIDKLANNIILEPVGRNTAPAIALAAFCALQN
                     ADNADPLLLVLAADHVIQDEIAFTKAVRHAEEYAANGKLVTFGIVPTHAETGYGYIRR
                     GELIGNDAYAVAEFVEKPDIDTASDYFKSGKYYWNSGMFLFRASSYLNELKYLSPEIY
                     KACEKAVGHINPDLDFIRIDKEEFMSCPSDSIDYAVMEHTQHAVVIPMSAGWSDVGSW
                     SSLWDISNKDHQRNVLKGDIFAHACNDNYIYSEDMFISAIGVSNLVIVQTTDALLVAN
                     KDTVQDVKKIVDYLKRNDRNEYKQHQEVFRSWGKYNVIDSGKNYLVRCITVKPGEKFV
                     AQMHHHRAEHWIVLSGTARVTKGEQIYMVSENESTFIPPDTIHALENPGMIPLQLIEI
                     QSGTYLGEDDIIRLEQRSGFSKEWTNERS"
     gene            1926..>2382
                     /gene="rfbK"
                     /locus_tag="OPV72_004356"
     CDS             1926..>2382
                     /gene="rfbK"
                     /locus_tag="OPV72_004356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen biosynthesis phosphomannomutase RfbK"
                     /protein_id="HCR9916485.1"
                     /translation="MNVVNNSRDVIHSSGIVFGTSGARGLVKDFTPQVCAAFTVSFVA
                     VMQEHFSFDTVALAIDNRPSSYGMAQACAAALADKGVNCIFYGVVPTPALAFQSMSDN
                     MPAIMVTGSHIPFERNGLKFYRPDGEITKHDEAAILSVEDTCSHLELKEL"
BASE COUNT          663 a          432 c          548 g          739 t
ORIGIN      
        1 atttggtatt aaaactgtat ttatgtccaa ttcttttgct gcctatcgcc gttccgtttt
       61 tgaagagtta agtgggtttc ctgaacatac aattcttgcc gaggatatgt ttatggcggc
      121 taagatgatt caggcgggtt ataaggtcgc ctactgcgct gaagcggtgg taaggcactc
      181 ccataattat accccgcgag aagagtttca acgatatttt gatactggtg tatttcatgc
      241 ttgttctccg tggattcagc gtgactttgg cggagccgga ggagagggtt tccgattcgt
      301 aaaatcagag attcaattcc tgcttaaaaa tgcaccgttc tggattccaa gagctttatt
      361 aacgaccttt gctaaattct tgggttacaa attaggcaag cattggcaat ctttaccgtt
      421 gtctacatgt cgctatttta gcatgtacaa gagttattgg aataatatcc aatattcttc
      481 gtcaaaagag ataaaataaa tgtcttttct tcccgtaatt atggctggcg gcacaggtag
      541 ccgtttatgg ccgctttcac gcgaatatca tccgaagcag tttttaagcg ttgaaggtaa
      601 actatcaatg ctgcaaaata ctataaagcg attagcttca ctttctacag aagaacccgt
      661 tgtcatttgc aatgacagac accgtttctt agtcgctgaa caactccgtg aaattgacaa
      721 gttagcaaat aatattattc tcgaaccagt aggccgtaat actgcaccag cgatcgctct
      781 tgccgcgttt tgtgcgctcc agaatgctga taatgctgat cctcttttgt tggttcttgc
      841 tgcagatcat gtgatccagg atgaaatagc gtttacgaaa gctgtcagac atgctgaaga
      901 atacgccgca aatggtaagc ttgtaacttt tggtattgtt ccaacgcatg ctgaaacggg
      961 ttatggatat attcgtcgtg gtgagttgat aggaaatgac gcttatgcag tggctgaatt
     1021 tgtggagaaa ccggatatcg ataccgccag tgactatttc aaatcaggga aatattactg
     1081 gaatagcggt atgtttttat ttcgtgcaag ctcttattta aacgaattga agtacttatc
     1141 acctgaaatt tacaaagctt gtgaaaaggc ggtaggacat ataaatcccg atcttgattt
     1201 tattcgtatt gataaagaag agtttatgtc atgcccgagt gattctatcg attatgcagt
     1261 tatggagcac acacagcatg ccgtggtgat accaatgagt gctggctggt cggatgtggg
     1321 atcctggtcc tcactttggg atatatcgaa taaagatcat cagagaaatg ttttaaaagg
     1381 agatatcttc gcacatgctt gtaatgataa ttacatttat tccgaagata tgtttataag
     1441 tgcgattggt gtaagcaatc ttgtcattgt tcaaacaaca gacgctttac tggtggctaa
     1501 taaagataca gtacaagatg ttaaaaaaat tgtcgattat ttaaaacgaa atgataggaa
     1561 cgaatataaa caacatcaag aagttttccg ctcttgggga aaatataatg tgattgatag
     1621 cggcaaaaat tacctcgtcc gatgtatcac tgttaagccg ggtgagaaat ttgtggcgca
     1681 gatgcatcac caccgggctg agcattggat agtattatcc gggactgctc gtgttacaaa
     1741 gggagagcag atttatatgg tttctgaaaa tgaatcaaca tttattcctc cggatactat
     1801 tcacgcgctg gaaaatcccg gaatgatccc cctgcagtta attgagattc aatcaggtac
     1861 ctatcttggt gaggatgata ttattcgttt agaacaacgt tctggatttt cgaaggagtg
     1921 gactaatgaa cgtagttaat aatagccgtg atgttattca ttcatcaggt attgtgtttg
     1981 gaacgagtgg ggctcgcggt cttgtaaaag attttacacc tcaggtatgt gctgctttta
     2041 cggtttcatt tgttgccgtt atgcaggaac atttttcctt tgataccgta gcattggcaa
     2101 tagataatcg tccaagtagt tatgggatgg ctcaggcgtg tgctgctgca ttggcagata
     2161 aaggcgttaa ctgtattttt tatggtgtgg taccaacccc ggctttggcc tttcagtcta
     2221 tgtctgacaa tatgcctgcg ataatggtta cgggaagtca tattccattc gagcggaacg
     2281 gcctcaagtt ttatcgtcct gatggtgaaa tcacgaaaca tgatgaggct gcgatcctta
     2341 gtgttgaaga tacgtgcagc catttagagc ttaaagaact ca
//
LOCUS       DAJVBX010000312         2255 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.313, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000312 DAJVBX010000000
VERSION     DAJVBX010000312.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2255
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.313"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(541..1107)
                     /locus_tag="OPV72_004357"
     CDS             complement(541..1107)
                     /locus_tag="OPV72_004357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005134158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Polarity suppression protein"
                     /protein_id="HCR9916486.1"
                     /translation="MTTVTIQQAFEACQTNKNTWLKRKAELADLEREYREQLLAGDEQ
                     IPRRMQDLRDNIDVKKWEINQAAGRYIRSHEEVQHISIRNRLHDFMQQHGAELAATLA
                     PELMGYHEQIPAVKQSAMQHSVDYLREALSVWLAAGEKINYSVQDNDMLTTIGFRPDA
                     ASRDDNREKFTPAQNLIYTRRRAELATR"
     gene            complement(1123..1362)
                     /locus_tag="OPV72_004358"
     CDS             complement(1123..1362)
                     /locus_tag="OPV72_004358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005225309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ogr/Delta-like zinc finger family protein"
                     /protein_id="HCR9916487.1"
                     /translation="MFHCPFCKKTAHVRTSRYLSENVKQRYHQCTNIECSATFRTIES
                     VDGVIRAAPEKPDPAPVTPPPPRKVQGCYSSPFRH"
     gene            complement(1366..2109)
                     /locus_tag="OPV72_004359"
     CDS             complement(1366..2109)
                     /locus_tag="OPV72_004359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001472073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HCR9916488.1"
                     /translation="MKPELIIKSMQTVISKQDEGAEQRIAGALVALNEAKDAHTASMG
                     KLSDIEASIQRCEQERQTALSESAQAEQDWRSRFRTLRGNLTPELKAEHSKRIASREL
                     ADEFTGLITELEKDKSLAMLGACSSGTAYISAHEKAFTTYANSEWKKALAGISPALLR
                     AFLLRIRSLEMSGETSLRATVTRELGDALNMQSALYHFDMEQEPVLSVTGMNRPVITG
                     VDMALLRSPARRMKLAAELAAKDHEQAEG"
BASE COUNT          483 a          596 c          591 g          585 t
ORIGIN      
        1 aagaatagaa taaagttgat aaagcaattg ttgcgcattg ctttccatct tgcattccac
       61 ccatgccatc taataacgcc attgcaaaaa aaggattgcc aacgtttgac ggagtgttaa
      121 ctctaatcgc ggctattaga tcctgattct cagctctaac cagtcctata tccgtgctaa
      181 ggacagcgtt gaggtcttct ggccggttaa tgccgctttt ggccgaagaa cgagctaacc
      241 agcgagcaag tcgttctgta aacatagtaa ttccgtttta ttgtggggga gtttactttc
      301 gcaatgagct aaccaattgt caattaatac gaaagagctc gcgcgcaatg ctctccccgc
      361 cacgcctgcc cgcttaagag gtcgctttta atgcaggtgc atgaacgtcc tcaggccgca
      421 ccagcactgg tgttgcgtgg gataaaaaat acggggattt gcatgcaaaa ccatgcacct
      481 tatggatgca tggctttttt caggaaaaat agcggaattt tcgggggatt ttttcgcgta
      541 ctaccgtgtg gccagttctg cacgtcggcg ggtgtaaatc aggttctgtg ccggagtgaa
      601 tttctcgcga ttatcatccc gcgaagccgc atcaggcctg aatccgatgg tcgttaacat
      661 atcgttgtcc tgcacggaat aattaatttt ttcacctgcg gccagccaca ccgacagggc
      721 ttcacgcaga taatcaaccg agtgctgcat ggcgctctgt tttactgcgg gaatttgttc
      781 gtgatatccc atcagctcag gcgccagcgt ggcggccagc tccgcgccgt gctgctgcat
      841 aaagtcatgg agccggttgc ggatgctgat gtgctgtacc tcctcatgtg agcggatata
      901 gcgaccggcg gcctgattaa tctcccactt tttcacgtcg atattgtcgc gcaaatcctg
      961 cattctgcgc gggatttgtt cgtcaccggc aaggagctgt tcacggtatt cccgttcaag
     1021 gtctgccagt tcggctttac gtttcagcca ggtatttttg ttcgtctgac aggcctcaaa
     1081 ggcctgctgt atggtcacag tggtcacgag tctctctcct gattaatgcc gaaacggcga
     1141 gctgtagcag ccctgtactt tacgcggcgg cggtggcgtc accggcgcgg ggtcgggttt
     1201 ctccggtgca gcacgtatca caccgtcaac cgactcaatg gtgcggaaag tggccgaaca
     1261 ttcgatattg gtacactggt gataacgctg tttgacgttt tccgacagat accggctggt
     1321 acggacgtgc gcggtctttt tgcagaacgg acagtgaaac ataattcagc cctctgcctg
     1381 ttcgtggtct tttgcggcca gttcagcggc aagcttcatc cgtctggccg ggcttcttaa
     1441 cagcgccata tcaaccccgg ttatgaccgg gcgattcatg cccgttacgg acagaaccgg
     1501 ctcctgctcc atatcaaaat gatacagggc tgactgcata ttcagggcat cacccagctc
     1561 acgggtcacg gtcgcacgca gcgaggtttc tccgctcatt tccagcgacc gaatacgcaa
     1621 cagaaaggca cgtaacagtg cggggctgat accggctaac gccttcttcc actcgctgtt
     1681 ggcgtaggta gtgaacgctt tttcatgggc gctgatataa gccgtaccgg aggagcatgc
     1741 accaagcatg gcgaggcttt tgtctttctc cagctcggta atcagaccgg tgaactcatc
     1801 agccagttcg cggctggcga tacgtttact gtgttcagct ttcagttcag gagtgaggtt
     1861 gccgcgcaga gttcgaaagc ggctgcgcca gtcctgttcg gcctgtgcac tttcactgag
     1921 ggcggtctgt cgttcctgct cacaacgctg aatggaagcc tcaatgtcgc tgagtttacc
     1981 catgctggcc gtgtgtgcgt cttttgcttc gttaagtgcg accagcgcac cggcaatgcg
     2041 ttgttccgcg ccttcatcct gtttactgat aacggtctgc atggatttga taatgagttc
     2101 gggtttcatg ttcaggctct ccgtgtgttc aacctgaaat gattctgacg cctcctgcac
     2161 aacaacacga ttcattgccg ttgtcagagt gctggcacaa acagacctta aaaaccggct
     2221 ggccacagaa aggtctcagg aaaacctgac tcacc
//
LOCUS       DAJVBX010000313         2203 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.314, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000313 DAJVBX010000000
VERSION     DAJVBX010000313.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2203)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2203)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2203
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.314"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..833
                     /gene="ppsR"
                     /locus_tag="OPV72_004360"
     CDS             <1..833
                     /gene="ppsR"
                     /locus_tag="OPV72_004360"
                     /EC_number="2.7.11.33"
                     /EC_number="2.7.4.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="posphoenolpyruvate synthetase regulatory
                     kinase/phosphorylase PpsR"
                     /protein_id="HCR9916489.1"
                     /translation="DNVVDRHVFYISDGTAITAEVLGHAVMSQFPVTISSITLPFVEN
                     ESRARAVKDQIDAIYQQTGVRPLVFYSIVLPEIRAIILQSEGFCQDIVQALVAPLQQE
                     MKLDPTPIAHRTHGLNPGNLNKYDARIAAIDYTLAHDDGISLRNLDQAQVILLGVSRC
                     GKTPTSLYLAMQFGIRAANYPFIADDMDNLTLPTSLKPLQHKLFGLTIDPERLAAIRE
                     ERRENSRYASLRQCRMEVAEVEALYRKNQIPCLNSTNYSVEEIATKILDIMGLNRRMY
                     "
     gene            989..2035
                     /gene="aroH"
                     /locus_tag="OPV72_004361"
     CDS             989..2035
                     /gene="aroH"
                     /locus_tag="OPV72_004361"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase AroH"
                     /protein_id="HCR9916490.1"
                     /translation="MNRTDELRTARIDSLVTPTELAQRYPVSSSVASHVTDSRRRIEK
                     ILNGEDPRLLVVIGPCSIHDLNAAMEYATQLQAQRQKHQARLEIVMRTYFEKPRTVVG
                     WKGLISDPDLNGSYRVNHGLELARRLLLQVNELGVPTATEFLDMVTGQFIADLISWGT
                     IGARTTESQIHREMASALSCPVGFKNGTDGNTRIAVDAIRASRASHMFLSPDKDGQMT
                     IYQTSGNPYGHIIMRGGKKPNYHAEDIAAACDTLHEFDLPEHLVVDFSHGNCQKQHRR
                     QLDVCDDICQQIRNGSTAIAGIMAESFLREGTQKIISGQPLIYGQSITDPCLNWEDTE
                     VLLEKLAAAVDSRF"
BASE COUNT          530 a          584 c          543 g          546 t
ORIGIN      
        1 tggataatgt tgttgatcgc catgttttct atatttctga tggtaccgcc atcaccgccg
       61 aggtcctggg tcacgcggtt atgtcgcagt ttccggtgac gatcagcagc atcacgctgc
      121 cattcgtgga aaacgaaagt cgcgcccgcg ccgtcaaaga ccaaattgac gccatttatc
      181 agcaaaccgg cgttcgcccg ctggtgtttt actcgattgt tttacctgaa attcgcgcca
      241 tcatcttgca gagcgaaggc ttctgccagg atatcgtcca ggcgctggtg gcgccgcttc
      301 agcaggagat gaaactggat ccgacgccga tcgctcatcg tactcatggg cttaatccgg
      361 gtaacctgaa caagtatgac gcccgtattg ccgctatcga ttataccctg gcgcatgatg
      421 atggcatttc attgcgcaac ctcgatcagg cccaggtcat tttacttggc gtttcgcgct
      481 gtggaaaaac gcccaccagt ctctatctgg caatgcaatt cggtattcgt gcggctaact
      541 accctttcat cgccgatgat atggataatt tgacgctgcc cacatcgtta aaaccgctac
      601 aacataaact gttcggcctg acaattgacc ctgaacgcct ggcggcaatt cgcgaagaac
      661 gccgtgaaaa cagtcgctat gcctcgttgc gtcagtgccg catggaagtg gcggaggtcg
      721 aagcgctgta tcgtaagaat cagatcccct gcctgaacag caccaattat tccgttgaag
      781 agatagccac caagattctc gatattatgg ggcttaaccg caggatgtac tagtaaacta
      841 gtttaatgga ttggtttttg ttatcatgcc gttctgcctg cgaggtgtga cacgcctcgc
      901 acttgaaatc agcagggatt ggtttatcgt gatgcccatc acttcccggt agtcctgccg
      961 ttgaaacaac aaatttctga gacttgtaat gaacagaacc gacgaactcc gtactgcgcg
     1021 tatcgacagc ctggtaacac caaccgaact cgcgcagcgg tatcctgtat cgtcctccgt
     1081 cgccagtcac gttaccgact cccgacgccg gatagaaaag attttaaatg gtgaagatcc
     1141 acggctactg gtcgtcattg gcccctgttc gattcacgat ctgaatgctg ccatggaata
     1201 cgcgacgcag ctccaggcac aacgccaaaa gcatcaggcg cgtctggaaa tcgtcatgcg
     1261 cacctatttt gaaaaaccgc gcaccgtcgt gggatggaaa ggcctgattt ccgatcccga
     1321 cttgaatggc agttaccgcg tcaatcatgg gcttgaactg gcgcgtcgct tgctattgca
     1381 ggtgaacgaa ctgggagtac cgaccgccac agaatttctt gatatggtca ccggccagtt
     1441 tattgccgat ctgatcagtt ggggaacgat tggcgcgcgt accaccgaaa gccaaatcca
     1501 tcgggaaatg gcttctgcgc tctcttgccc ggtcggcttt aaaaatggta cggatggcaa
     1561 tacccgcatt gccgttgatg ctattcgcgc ctcccgcgcc agtcatatgt ttctctcgcc
     1621 ggataaagac ggacagatga ctatctacca aacgagtggc aacccgtatg ggcacatcat
     1681 catgcgcggc ggtaaaaaac cgaactacca cgctgaagat attgccgccg cctgcgacac
     1741 gttgcatgaa tttgatctgc cggaacatct ggtcgtcgac ttcagccacg gcaactgtca
     1801 aaaacagcat cgccgccagt tggacgtatg tgatgatatt tgccagcaga ttcgtaatgg
     1861 ctccacggca attgccggga ttatggcaga gagtttttta cgggaaggca cgcaaaaaat
     1921 tatcagcggt caaccgttaa tctatggtca atccattacc gatccctgcc tgaactggga
     1981 agatacggaa gttctgttgg aaaaacttgc cgcggcggta gacagccgct tttaatagct
     2041 cgcccatcct gccgggatgg gcgtttcttc gatgcgttac ccaccctttt ctctacgcgc
     2101 gcgtatatca ctccacagaa ttagcacttg ctgttatcgc attaattatt gataataata
     2161 atcattgtga gtttgattat taataaataa catgtcgcgt atg
//
LOCUS       DAJVBX010000314         2197 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.315, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000314 DAJVBX010000000
VERSION     DAJVBX010000314.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2197)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2197)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2197
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.315"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            3..647
                     /locus_tag="OPV72_004362"
     CDS             3..647
                     /locus_tag="OPV72_004362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000018003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCR9916491.1"
                     /translation="MQNQHEGCCKNQDHKHDGCCKDREHQHEGCHSAHQHENASCGGE
                     HRHGHGCGRHGQGGGRRQRFFGHGELRLVILDILTRDASHGYELIKAIENLTGGGYTP
                     SAGVIYPTLDFLQDQQFITISDEEGGRKKIAITANGAQWLDENREHLTHIQARLKARC
                     VGMELRKNPQMKRALDNFKAVLDLRINHSDINDAQIKRIIGVIDRAALEIAELD"
     gene            complement(644..2197)
                     /locus_tag="OPV72_004363"
     CDS             complement(644..2197)
                     /locus_tag="OPV72_004363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MCP four helix bundle domain-containing protein"
                     /protein_id="HCR9916492.1"
                     /translation="MKIRSKLFMAFGLFIVLMVVSSALSLFSLDRANTGMQDIITNDY
                     PTTVKANLLIDNFNDFIIAQQLMLLDEEGRWSQSSQKELSEISQRISALLDELSRENS
                     HDADSQKIINEIREARQQYLESRFRILKDIQSNNRQAAIQEMMTRTVQVQKVYKDKVQ
                     ELIAVQDALMHEASVQVKEDFKNNRTLLITLALISIAAGGVIGWYIVRSITRPLDDAV
                     RFAEAIADGDLTRHITTDYKDETGVLLQALMAMKTRLLDIVQEVQNGSESISTAAAQI
                     VAGNQDLAARTEEQASSVEETAASMEQITATVKNTADHTSEATKLSAGAASVVKNNGE
                     MMNQVTQKMRVINDTANRMSDIINIIDSIAFQTNILALNAAVEAARAGEHGRGFAVVA
                     GEVRQLAQKSASSASEIRNLIEDSTSQTQEGMHLVEKASALINGMVDNVEEMDVILRE
                     IGQASREQTDGISQINSAIGLIDAATQQNSCLVEESVAAAASLNEQALHLKELVNVFR
                     VREEDTQPA"
BASE COUNT          523 a          585 c          542 g          547 t
ORIGIN      
        1 tgatgcaaaa tcaacatgaa gggtgttgca aaaaccagga tcataagcac gacggctgct
       61 gtaaagatcg agaacatcag catgaaggct gccatagcgc gcatcagcat gagaacgcca
      121 gttgcggcgg cgaacatcgt cacggacacg gctgtggtcg tcatggacag ggcggtggtc
      181 ggcgtcagcg attttttggc cacggggaac ttcggctggt cattcttgat atcctgaccc
      241 gggacgccag ccacggctat gaactgatta aagcgataga aaacctgacg gggggcggct
      301 atacgccaag cgctggcgtg atctacccta cgctggattt tttacaggat cagcaattta
      361 tcacgattag cgacgaagaa ggcgggcgga aaaaaatcgc gattaccgcg aacggcgcgc
      421 aatggcttga tgaaaatcgc gaacatctga cgcatattca ggcgcggcta aaagcccgtt
      481 gtgtgggcat ggagttacgt aaaaatcctc agatgaagcg ggcgctggat aacttcaagg
      541 ccgtgctgga tctgcggata aaccacagcg atatcaacga cgcgcaaatc aaacgcatta
      601 tcggcgtgat tgatcgcgcg gcgctggaaa tcgccgaact ggattaagcg ggctgcgtgt
      661 cctcttcgcg gacgcggaac acgttaacca gctcttttaa atgtaacgcc tgttcgttca
      721 gcgacgctgc ggcggcaaca gactcttcca caaggcagga gttttgttgc gtggcggcgt
      781 caatcaggcc aatcgcgctg ttaatctgcg aaataccgtc agtttgctcg cggctggcct
      841 gcccaatctc acgtaatatc acatccatct cttcgacgtt gtccaccatg ccattaatca
      901 gggcgctggc tttctccacc aggtgcatcc cttcctgagt ctgactggtt gaatcttcaa
      961 tcaaattacg gatttcactg gccgacgagg cgctcttttg cgccaactgg cgaacctctc
     1021 cggcgacaac ggcaaaaccg cgcccatgtt cgcccgcgcg cgccgcttca accgccgcgt
     1081 tcagcgccag aatattggtc tgaaaggcaa tggaatcaat gatattgatg atatccgaca
     1141 tacgatttgc cgtatcgtta atgacgcgca ttttctgcgt cacttgattc atcatctccc
     1201 cattgttttt cactacgctg gcggcgccag cagagagttt ggtcgcttca ctggtatgat
     1261 cggctgtgtt tttaaccgtg gcggtaatct gttccatcga cgccgccgtt tcttcaaccg
     1321 agctggcctg ctcttccgta cgcgccgcca aatcctggtt accggcgaca atttgcgccg
     1381 ccgccgtgga gatactctcc gaaccgtttt gcacttcctg tacgatatcc agcagacgcg
     1441 ttttcatcgc cattaacgct tgcagtagta cgcctgtttc atctttatag tcggtggtga
     1501 tatggcgagt cagatcgcca tcggcaatcg cctcggcaaa gcgtaccgcg tcatcaagcg
     1561 gtcgggtaat agaacgcaca atataccatc ctattacgcc tccggcggcg atgcttatca
     1621 gcgccaaagt gattaacaac gtccgattat ttttaaaatc ctctttgacc tgcacgctcg
     1681 cttcatgcat cagcgcgtcc tgaacagcga taagttcctg gactttgtcc ttatagactt
     1741 tttgcacctg caccgttctg gtcatcatct cctgaatggc cgcctgacga ttattgcttt
     1801 gaatatcttt caaaatacgg aatctggact ccaggtattg ctggcgcgct tcacggattt
     1861 cattaatgat tttctgtgaa tccgcatcgt gactattttc cctggaaagc tcatccagta
     1921 acgccgaaat gcgctggctt atctcactga gttctttctg cgagctctgg ctccagcgcc
     1981 cctcttcatc cagtaacatg agctgctgcg cgatgatgaa atcattaaaa ttatcgatta
     2041 acagattggc ttttaccgtg gtgggataat cattggtaat aatgtcctgc atacccgtat
     2101 tagcccgatc aaggctaaac aaagacagag cggaactcac caccatgaga acaatgaata
     2161 agccaaaggc cataaataat tttgaacgta ttttaat
//
LOCUS       DAJVBX010000315         2161 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.316, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000315 DAJVBX010000000
VERSION     DAJVBX010000315.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2161)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2161)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2161
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.316"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..503
                     /locus_tag="OPV72_004364"
     CDS             <1..503
                     /locus_tag="OPV72_004364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ferritin-like domain-containing protein"
                     /protein_id="HCR9916493.1"
                     /translation="YTEHYHDWLRDAHAMEKQAESMLESMASRIENYPDIKARIEQHI
                     SETKHQITMLEEVLDRNGISRSVLKDSMSKMAAMGQSIGGMFPSDEIVKGSISGYVFE
                     QFEIACYTSLLAAAKKAGDTASIPTIEAILKEEMQMADWLIKHIPQTTEQFLLRSEAD
                     GVEAKK"
     gene            523..1401
                     /locus_tag="OPV72_004365"
     CDS             523..1401
                     /locus_tag="OPV72_004365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HCR9916494.1"
                     /translation="MFRHVKQLQYTVRVSEPNPGLANLLLEQFGGPQGELAAACRYFT
                     QGLSDDDAGRREMLMDIATEELSHLEIIGSLVGMLNKGAKGELAEGTESEAELYRSLT
                     QNGNDSHITSLLYGGGPALTNSGGVPWTAAYIDTIGEVTADLRSNIAAEARAKIIYER
                     LINLTDDPGVKDTLSFLMTREVAHQLSFEKALYSIRNNFPPGKLPPVEQYTDVYYNIS
                     QGDDPRGSWNSDENFNYVAEPMPAVDGGDGLATVKLPREQMALLKAMAERTKSDPTVD
                     PLTGAELGCGEPKEDK"
     gene            complement(1483..2121)
                     /gene="ompW"
                     /locus_tag="OPV72_004366"
     CDS             complement(1483..2121)
                     /gene="ompW"
                     /locus_tag="OPV72_004366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein OmpW"
                     /protein_id="HCR9916495.1"
                     /translation="MKKFTVAALALTTLLSGSAFAHEAGEFFMRAGPATVRPTEGAGG
                     TLGHLNGFDVSNNTQLGLTFTYMATDNIGVELLAATPFRHKVGTGATGDIATVHLLPP
                     TLMAQWYFGDSSSKVRPYVGVGVNYTTFFDNDFNDNGKKTGLSDLSFKDSWGAAGQVG
                     VDYLINRDWLIGASVWYMDIDTTANYKMGGVQQHDSVRLDPWVFMFSAGYRF"
BASE COUNT          579 a          552 c          541 g          489 t
ORIGIN      
        1 attatactga acattatcat gactggcttc gtgacgccca tgccatggaa aaacaggcag
       61 aatcgatgct tgaatctatg gccagccgta ttgaaaatta tcctgatata aaagccagaa
      121 ttgaacaaca tattagtgaa accaaacatc aaattaccat gctcgaggaa gtgttggacc
      181 gtaatggcat ttcccgttcg gtgttgaaag actccatgag taaaatggca gcaatggggc
      241 aatctatcgg tggcatgttc ccttccgatg aaattgtcaa aggctcaatt agcggttatg
      301 ttttcgagca gttcgaaatt gcttgttata cctccctgct ggcggcggca aaaaaagctg
      361 gcgacactgc ctcaattcca acgattgaag ccattctgaa agaagaaatg caaatggctg
      421 actggcttat caaacatatt ccgcagacaa cggaacaatt tttactgcga tctgaagcag
      481 atggcgttga agccaaaaaa taaataataa gcaggaggca atatgtttcg acacgtaaaa
      541 caacttcaat atactgtgcg agtgagcgaa cctaatcctg gattagcgaa cctgctgctg
      601 gaacagtttg gcggcccgca gggcgaactg gcggccgcct gccgctactt cacgcaaggt
      661 ttaagcgatg atgatgccgg tcgtagagag atgttaatgg acatcgccac cgaggagctg
      721 agtcatctgg aaattatcgg ctcactggta ggaatgctta ataaaggcgc taaaggcgag
      781 ctggcggaag gcaccgaaag cgaagcggaa ctttatcgct cgctgacgca gaatggtaat
      841 gacagccata tcacctctct gctgtatggc ggcggccctg cgttgacaaa ctccggcggc
      901 gtaccgtgga ccgcggctta tattgatact atcggcgaag tcacagccga tctacgctca
      961 aacatcgcgg cagaggcgcg agcgaagatt atttatgaac gcctgattaa cctgaccgac
     1021 gatcctggcg taaaagacac gctcagtttc ttaatgaccc gtgaagtcgc gcaccagctc
     1081 tcttttgaaa aggcgctgta ttcgattcgt aacaacttcc cgccgggtaa attaccgccg
     1141 gtagaacagt ataccgacgt gtactacaac atatcgcaag gcgacgatcc gcgaggtagc
     1201 tggaatagcg atgagaactt caactatgtc gcagaaccga tgcctgctgt tgatggcggc
     1261 gatggcctgg cgacagtgaa attgccgcgc gagcagatgg cgctgctcaa agcgatggca
     1321 gaaagaacga aatcggaccc caccgttgat cctctcactg gcgcagaact aggctgcggc
     1381 gaaccgaaag aagacaagtg agttccgaca agtaaaatcc gtgtgtcatg tccttttttg
     1441 accccgcctg gcggggtctt ttttcgtcac aacatcacgc gattagaaac gatagcctgc
     1501 cgagaacata aatacccatg ggtccagacg cacgctgtca tgctgctgca cgccgcccat
     1561 tttataattg gctgtagtat caatatccat gtaccagaca gaggcgccaa ttaaccagtc
     1621 gcggttaatc aggtaatcta ccccaacttg ccctgccgcg ccccaggaat ccttaaagct
     1681 cagatcggac agcccggtct ttttaccatt atcgttaaag tcgttatcga agaaggtggt
     1741 gtagttcacc cccacgccga cataaggacg cactttgctg ctggaatcgc cgaagtacca
     1801 ctgcgccatt aacgttggcg gtaacaggtg gaccgtggcg atatcacccg tcgcgcccgt
     1861 acccacctta tggcggaacg gcgtggccgc cagcaattca accccgatat tgtccgtcgc
     1921 catgtaagtg aatgtcaggc cgagttgcgt gttattactc acatcaaacc cgtttaaatg
     1981 ccccagcgta ccacccgccc cttctgtagg tctgacggtt gccggacctg cacgcataaa
     2041 gaattctccg gcttcgtgcg cgaacgcgct gcctgagaga agagttgtta acgccagtgc
     2101 cgccactgta aattttttca tacccgctcc atcgttatgg ttataaaagc gtgatgaata
     2161 t
//
LOCUS       DAJVBX010000316         2123 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.317, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000316 DAJVBX010000000
VERSION     DAJVBX010000316.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2123)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2123)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2123
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.317"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            439..1106
                     /locus_tag="OPV72_004367"
                     /pseudo
     CDS             439..1106
                     /locus_tag="OPV72_004367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611920.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            1078..1200
                     /locus_tag="OPV72_004368"
                     /pseudo
     CDS             1078..1200
                     /locus_tag="OPV72_004368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415069.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
     gene            complement(1222..1298)
                     /locus_tag="OPV72_004369"
     tRNA            complement(1222..1298)
                     /locus_tag="OPV72_004369"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1262..1264),aa:Arg,seq:tct)
     gene            1553..>2123
                     /gene="fimW"
                     /locus_tag="OPV72_004370"
     CDS             1553..>2123
                     /gene="fimW"
                     /locus_tag="OPV72_004370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria biosynthesis transcriptional regulator
                     FimW"
                     /protein_id="HCR9916496.1"
                     /translation="MLSIAIKEQNSHFEHGLKIIMTRLANQWQQKIDFLPPEEIDNAD
                     IAFLTLDDDWFSAGCYQIPMHTQHQLRVIICNKCDKEKLMFRPCLYMLPHIYREDDVE
                     EITRKMILILHKRALRHSVPSGICHYCTTRHFSVTERHLLKLIASGYHLSETAALLSL
                     SEEQTKSLRRSIMRKLHVKTEQQFLKYIRV"
BASE COUNT          655 a          472 c          484 g          512 t
ORIGIN      
        1 acgttagaac aggggcgagg acaaatgaga atattacgga aataattaaa taacattcat
       61 gtataattaa tgttccccgc caccaatggg taacgggcgg cggggattcc tacatatcgt
      121 atgtcacaaa tgccccatca ggtttcttag caagaagtcg caatgcgcca tcagtcccaa
      181 aaaagaaccc aacggagcca tagtgcatta atccagactc cggcaactga ccaatacacg
      241 caggatacgc atgtgcccaa agcccatccg gttcaactcc accacagatg caggaacacc
      301 gtcttttagt gcggataaac tgacccctac tggtttcact accgggtaaa ggaatctgat
      361 aatctgcggt caatgtgaat caccacaggt ttaacagaca cctcagatcc atttaagatg
      421 acttaaagag aggtgcctat gagcggtaaa cgttatcccg aagagtttaa aattgaagcg
      481 gtaagacagg ttgttgagcg cggccattct gtttccagcg tcgcaacaca tctcgatatt
      541 actacccaca gtctttacgc caggataaag aagtacgggt cgaactcctc caccaataaa
      601 gaaataaaga gcagtcagat gatcagaccg gaatccgccg actcccgaaa gagttgaagc
      661 gggttactga cgaacgggac atattaaaaa aagccgcagt agactcaatt ggtcactgca
      721 accatgaatg acaaaagatg gagtcctgaa tgcgctcctg atggccgtgt ggcgacataa
      781 tcacccgcta tgaatggcag tcgatcctga aatcgcacgg actggagggc agtatgagcc
      841 gtcgtggcaa ctgtcatgaa aatgcggttg cagaaagctt tttccagcta ctgaagcgtg
      901 aacggataaa gaaaaagatc tacggaacga gagacgaagc cagaagcgat atttttaatt
      961 acatagaaat gttttataac agtagacgtc ggcatggttc gagcgagcag atgccaccgg
     1021 ctgaatatga aaacctatat catcaacgac tcagaagtgt ccaggttatc cgtggcgatt
     1081 cacagatatg ctcaccttgc gcctaatcat ttaacggaac acgcgaggaa aatagacgac
     1141 atttttggtg atgatgtccc aaatatgtcc catatggaaa ataaggagga aataaagaag
     1201 cgtaacgcgt tgatttataa gtggcgcgcc ctgcaggatt cgaacctgcg acccacggct
     1261 tagaaggccg ttgctctatc caactgagct aagggcgcct tgtgaagtga agacttcatg
     1321 tagacgaaac gcgagaatta tacggtcagg cactcctgag tcaatggctt ttgttctggt
     1381 tgctgactaa gtgtacgaat atcgtctttt ctggcgcaat gccaggttcc aggaaatcgc
     1441 ctggacacat ctcagcacgc ataaagtggg aattaaagcc gccagtattt agataatcaa
     1501 tcagtttctt taatatttca ccatgactca cctgccgtgt aggatatttt ttatgctgag
     1561 tatcgctatt aaggaacaaa acagtcactt tgagcatggt ttgaaaatca tcatgacgcg
     1621 tctggcgaat caatggcagc agaaaattga ctttctgccg ccagaagaga tagataatgc
     1681 cgatatcgct ttcctgaccc tggatgatga ttggttcagc gcaggctgtt accagatacc
     1741 tatgcatact caacatcagc tacgggtaat tatttgtaat aaatgcgata aagaaaagct
     1801 catgttcaga ccatgtctgt atatgctgcc gcatatttat cgggaagatg atgttgaaga
     1861 aattacccgg aaaatgatat tgatcttaca taagcgagcg cttcgacata gcgtcccttc
     1921 tggcatctgc cactactgca cgactcgcca tttttcagta acagaacgtc acttattaaa
     1981 actgatcgcc agcggttatc atttaagcga aacggccgct ttactttcac tttctgaaga
     2041 gcagacaaag tcactccgcc ggagcattat gcgaaaatta catgttaaaa cggagcagca
     2101 gtttttaaaa tatattagag tta
//
LOCUS       DAJVBX010000317         2116 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.318, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000317 DAJVBX010000000
VERSION     DAJVBX010000317.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2116
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.318"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            75..617
                     /locus_tag="OPV72_004371"
     CDS             75..617
                     /locus_tag="OPV72_004371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012016429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 108 protein"
                     /protein_id="HCR9916497.1"
                     /translation="MTKDEIFAAILSREGGYVDHPDDRGGPTHWGITLTTARANGYMG
                     DMRNLTRNQALKILEADYWYGPRLDQVAIISHSIAAELCDTGVNMGPSIPIKYFQRWL
                     NVFNDQQKIYPDLIADGQIGPRTLSALTFFLSHRRDEGEMILIRALNCSQGQRYLELA
                     EKRQANESFVYGWIKERVRL"
     gene            complement(765..1142)
                     /locus_tag="OPV72_004372"
     CDS             complement(765..1142)
                     /locus_tag="OPV72_004372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1353 domain-containing protein"
                     /protein_id="HCR9916498.1"
                     /translation="MSCFTSPAIMEMLGHYKWRVYEPFRFYLSEDKNDVIEVPVGFVT
                     DLATVPRIFWSLLPPDGEYAKAAIIHDYLYHYPLRNRKESDLIFLDGMKVLGVPKWKR
                     IIMYLAVRIFGWKYYHSHTIQHN"
     gene            complement(1215..2024)
                     /gene="cdtB"
                     /locus_tag="OPV72_004373"
     CDS             complement(1215..2024)
                     /gene="cdtB"
                     /locus_tag="OPV72_004373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001529135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytolethal distending toxin S-CDT"
                     /protein_id="HCR9916499.1"
                     /translation="MKKPVFFLLTMIICSYISFACANISDYKVMTWNLQGSSASTESK
                     WNVNVRQLLSGTAGVDILMVQEAGAVPTSAVPTGRHIQPFGVGIPIDEYTWNLGTTSR
                     QDIRYIYHSAIDVGARRVNLAIVSRQRADNVYVLRPTTVASRPVIGIGLGNDVFLTAH
                     ALASGGPDAAAIVRVTINFFRQPQMRHLSWFLAGDFNRSPDRLENDLMTEHLERVVAV
                     LAPTEPTQIGGGILDYGVIVDRAPYSQRVEALRNPQLASDHYPVAFLARSC"
BASE COUNT          620 a          437 c          449 g          610 t
ORIGIN      
        1 ttttttatca gattcattgc attaccaatc atagcattca ggtacgtatt ttattaatat
       61 tagaaggagt cattatgact aaagatgaaa tctttgcagc tatccttagt agagaaggcg
      121 gttacgttga tcaccctgac gacagggggg ggccaacgca ttggggtata accctgacga
      181 cggcccgggc taatggctat atgggggata tgcggaatct tacccgtaat caagcattaa
      241 aaatccttga ggcagattat tggtatggtc cacgacttga tcaggttgcc attatctctc
      301 actctattgc agctgagctt tgtgatactg gtgtgaacat gggaccctca atcccgatta
      361 agtacttcca gcgttggctt aatgttttta atgatcagca aaaaatttat ccggatttga
      421 tagcagatgg tcagattggg ccacggacgc tttcggcact aacatttttt ctctctcacc
      481 ggagagatga gggcgaaatg atacttatcc gggcattgaa ttgtagtcag ggacaacgct
      541 atctggagtt agctgaaaag cgccaggcga atgaatcatt tgtttatgga tggataaagg
      601 aacgggtaag attgtaattc ccttacttac cactatagcg gtttgtgatg atagcatata
      661 atgatatatt cacacagaga actggtgaaa gccactaagt ctcattatta ctatattaag
      721 gcgtcaggtt tttctatagt tctttgtgtg ttaaaaacga gaaattaatt atgttgtatg
      781 gtatgagaat gatagtattt ccagccaaat attcttacgg ctaaatacat tattatcctt
      841 ttccattttg gcacgcccag aactttcatc ccatccagga atatgagatc ggactctttt
      901 ctgttacgta atggataatg atacaggtag tcatgaatga ttgccgcttt ggcatattca
      961 ccatccggtg gcaataatga ccagaaaata cgcggaacag tggcaaggtc ggtaacgaat
     1021 cctaccggta cttcaatgac atcattttta tcttcactga gataaaacct gaatggctca
     1081 taaacacgcc atttataatg acctaacatt tccataattg ctggactggt aaaacaactc
     1141 ataattttac cttataataa atatatattc tgcaccttac gctcaaagta catgtcgtaa
     1201 actctattta ctcattaaca gcttcgtgcc aaaaaggcta cgggataatg atcagaagcg
     1261 agttgtggat tacgtaatgc ttcaaccctt tgtgaataag gtgctcgatc gacaatgacc
     1321 ccataatcta aaataccacc gccaatttgc gtgggttctg taggtgcgag tacggctaca
     1381 actcgttcca gatgctcagt catcaggtca ttttcaagtc tgtctgggct gcgattaaaa
     1441 tccccggcaa gaaaccagga taaatgccgc atctgaggtt gtctaaaaaa attaatggta
     1501 accctgacaa tagctgcagc atccggacct ccactagcca gtgcgtgcgc tgtcagaaaa
     1561 acatcattac ccagtccgat gccaatgacg gggcgagatg cgacagttgt cggacgcaag
     1621 acataaacat tatccgctct ttgtctggaa actattgcca gattaacacg gcgtgctcca
     1681 acatcaatag ccgagtggta gatatatctt atatcctgac ggctggtggt tccgagattc
     1741 caggtgtatt catcaatggg aatacccact ccaaaaggct gaatatgtcg tccggtagga
     1801 accgctgagg tgggaacagc accggcctcc tgtaccataa gaatatccac accggcagta
     1861 ccacttaaaa gctgtctgac attgacattc catttacttt ctgtagatgc tgaagagccc
     1921 tgaagattcc aggtcataac tttgtagtca ctgatattag cgcaggcaaa agaaatatag
     1981 ctgcagatga tcatggtcag aaggaaaaaa acaggttttt tcataatatc tactctcccg
     2041 agcattactt ctttatctga atgatatatg tgttaataac ccattgtttc atgacgttga
     2101 ttttattctg gcaatg
//
LOCUS       DAJVBX010000318         2098 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.319, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000318 DAJVBX010000000
VERSION     DAJVBX010000318.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2098)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2098)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2098
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.319"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            446..880
                     /gene="uspF"
                     /locus_tag="OPV72_004374"
     CDS             446..880
                     /gene="uspF"
                     /locus_tag="OPV72_004374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspF"
                     /protein_id="HCR9916500.1"
                     /translation="MNRTILVPIDISDSELTQRVISHVEAEAKIDDAKVHFLTVIPSL
                     PYYASLGLAYSAELPAMDDLKAEAKSQLEAIIKKFNLPADRVQAHVAEGSPKDKILEM
                     AKKLPADMVIIASHRPDITTYLLGSNAAAVVRHAECSVLVVR"
     gene            complement(933..1271)
                     /locus_tag="OPV72_004375"
     CDS             complement(933..1271)
                     /locus_tag="OPV72_004375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HCR9916501.1"
                     /translation="MTKEAVIFLFIAIVVEVIATISLKLSDSFTRLVPSLVTIIGYCI
                     AFWCLTIPMRTIPAGIIYAIWSGVGIVLIGLIGWLFLGQKLDVPAIIGMLLIICGVIV
                     INLFSKSVSH"
     gene            complement(1546..2098)
                     /locus_tag="OPV72_004376"
                     /pseudo
     CDS             complement(1546..2098)
                     /locus_tag="OPV72_004376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010835222.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="DUF4765 family protein"
BASE COUNT          599 a          499 c          407 g          593 t
ORIGIN      
        1 cccgaacatc cgttcgggct tgtcaattta tacgctggaa agcaaaggtt aacgcaatgg
       61 cccaacgaca aaatgaatat gtgacaataa aggcatataa caggcgtaga atatcgtaac
      121 cgaatgatat tgtataattt ttatttcgta taatacccct aaaagcattc gtataaatta
      181 tatctatttc actgcgaatt atttcattaa ttattgaatt aaacggtaac atctcttttt
      241 aggtctttcc tgacaaggca gaaataacgt tttaacgtca actcgctgat tatttacggg
      301 gaatgcgctt aatattacgc cgtcctcccc tgttggtagt ccccccagag tatcgtggag
      361 cagcacctaa aatgtgacgt atgtcattgt acataaagtg cctttaggga gtagaatttc
      421 agtggatact taaacaggag gttttatgaa cagaacgatt cttgtaccca tcgatatttc
      481 agattcagaa ttaactcaac gcgtgatttc acatgttgaa gccgaagcaa agattgacga
      541 cgctaaagtg cactttttga ctgtaatccc gtctttgccc tattacgctt cactgggact
      601 ggcttattca gcagagctcc ccgcaatgga cgatttgaaa gccgaagcca aatctcaact
      661 ggaagcgatt atcaagaaat tcaaccttcc cgcggaccgc gtgcaggcgc acgtggcaga
      721 aggctctcct aaagataaga ttctggaaat ggcaaaaaaa ttaccggccg atatggtgat
      781 tatcgcctcg catcgtccgg atattactac ctatctgttg ggttccaacg ccgcagccgt
      841 tgtgcgtcat gcggaatgct ccgtactggt ggtgcgctaa atacccgagc ccgcataaga
      901 gagtgcgggc tcaaatcaac catcatcatc gcctagtgac tgacgctttt tgaaaacaga
      961 ttgattacga ttacaccgca gatgataagc aacatgccaa taatagccgg cacatccaat
     1021 ttttggccaa gaaacagcca tcctatcaat ccaataagaa caatccctac cccagaccaa
     1081 atggcataaa tgatacccgc agggatggtt cgcataggga tggtaaggca ccagaacgcg
     1141 atacaatatc cgatgatggt aacgaggctc ggtaccagac gcgtaaaact atccgataat
     1201 tttaatgaga tcgtggcgat aacttctacc acgatggcga taaatagaaa gattacagct
     1261 tctttagtca tacatctctt cgttccgata tttttctggt cgtggtgaca tcttaattaa
     1321 tacggatgac agaataaaga cgcttttgac ccgttgcgta tctcgccata acctacttca
     1381 agttgcatgt gctgcagctg cgttccctta ccccagtcac ttacttgagt aagctcctgg
     1441 ggattcgctc gcttgccgcc ttcctgcaac tcgaattaat taaagtataa aagcaacctt
     1501 tcatacacga gagataacaa caataaacct gttcaggatt tatgattact tagaagcgtt
     1561 tgcctgcccc gtattttctg ctttaccata tgtcctgtca attataccaa cagggtccac
     1621 tggtgtgttt tttggcataa cccagccact ttcactgaca ctacctcgtg taagatattt
     1681 gacttttacc ctaacgataa taagataatg ttccctgctg aacctgtcgg caacactaag
     1741 atcggtggta tattcaggta cgattcttcc acttcgaacc tgctctttgg ctatttcagc
     1801 agagacaggc aatacctcta catcgccccc tcaataccgc ctgctgtttt aaaactaaca
     1861 atattttcag cctgcggacc tattgtacct cggcataata caacttcagt ctcccctgct
     1921 acagcatccc cactctggta tttcttataa atactttgta cattttcttc tgatgtaggg
     1981 tataaatttt ctgacagaga ggccagtata tcttccagta agggggaatc atccgtaata
     2041 tccagaagct cttcatcata acccgtgtct ccttctctta actctgaata aggcttat
//
LOCUS       DAJVBX010000319         2087 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.320, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000319 DAJVBX010000000
VERSION     DAJVBX010000319.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2087)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2087)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2087
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.320"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..830)
                     /gene="tviC"
                     /locus_tag="OPV72_004377"
     CDS             complement(<1..830)
                     /gene="tviC"
                     /locus_tag="OPV72_004377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Vi polysaccharide biosynthesis
                     UDP-N-acetylglucosaminuronic acid C-4 epimerase TviC"
                     /protein_id="HCR9916502.1"
                     /translation="MTAYEELRTKLVLAPKRWLITGVAGFIGSGLLEELLFLNQTVIG
                     LDNFSTGYQHNLDDVRTSVSEEQWSRFIFIQGDIRKFTDCQKACKNVDYVLHQAALGS
                     VPRSLKDPIATNSANIDGFLNMLTAARDAHVSSFTYAASSSTYGDHPDLPKIEERIGR
                     PLSPYAVTKYVNELYADVFARSYEFNAIGLRYFNVFGRRQNPNGAYSAVIPRWILSLL
                     KDEPIYINGDGSTSRDFCYIENVIQANLLSATTNDLASKNKVYNVAVGDRTSLNELYY
                     L"
     gene            complement(833..>2087)
                     /gene="tviB"
                     /locus_tag="OPV72_004378"
     CDS             complement(833..>2087)
                     /gene="tviB"
                     /locus_tag="OPV72_004378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="Vi polysaccharide biosynthesis
                     UDP-N-acetylglucosamine C-6 dehydrogenase TviB"
                     /protein_id="HCR9916503.1"
                     /translation="IAIIGLGYVGLPLAVEFGKSRQVVGFDVNKKRILELKNGVDVNL
                     ETTEEELREARYLKFTSEIEKIKECNFYIITVPTPINTYKQPDLTPLIKASETVGTVL
                     NRGDIVVYESTVYPGCTEEECVPILARMSGMTFNQDFYVGYSPERINPGDKKHRLTNI
                     KKITSGSTAQIAELIDEVYQQIISAGTYKAESIKVAEAAKVIENTQRDLNIALVNELA
                     IIFNRLNIDTEAVLRAAGSKWNFLPFRPGLVGGHCIGVDPYYLTHKSQGIGYYPEIIL
                     AGRRLNDNMGNYVSEQLIKAMIKKGINVEGSSVLILGFTFKENCPDIRNTRIIDVVKE
                     LGKYSCKVDIFDPWVDAEEVRREYGIIPVSEVKSSHYDAIIVAVGHQQFKQMGSEDIR
                     GFGKDKHVLYDLKYVLPAEQSDVRL"
BASE COUNT          560 a          490 c          432 g          605 t
ORIGIN      
        1 agataataaa gctcatttaa cgaagttcta tctccaactg ccacattata gaccttattt
       61 ttagaggcta aatcattagt tgttgctgat aatagattgg cctgaatcac attctctata
      121 tagcaaaaat ccctgcttgt tgagccatcg ccattgatat aaattggttc atctttaaga
      181 agcgatagta tccagcgagg aataactgcc gagtacgctc cgttaggatt ttggcggcga
      241 ccaaagacat taaagtagcg taggccaata gcgttaaatt catagctacg tgcaaacaca
      301 tcagcgtaca attcattgac gtattttgtt accgcatacg ggctgagtgg tcgaccgatc
      361 cgttcctcaa ttttaggtaa atcgggatgg tctccatagg tgctactgct tgcggcgtag
      421 gtgaaactag agacatgagc atctctcgcc gccgtcaaca tatttaaaaa accatcaata
      481 ttggcgctat tagtcgcgat gggatccttt agggaacgtg gcacgcttcc tagcgcggct
      541 tggtggagaa catagtcaac gttcttacac gctttctgac agtcagtaaa tttcctgatg
      601 tcaccctgaa taaaaataaa tcgcgaccat tgctcctcac tgacggacgt gcgaacgtcg
      661 tctagattat gctgataacc ggtggaaaag ttatccagtc caatgacagt ctggttgaga
      721 aagagtaatt cttctaataa gccggagcca ataaagcctg ctacgccagt gatcagccag
      781 cgctttggtg ccagaaccag tttggtccgt agttcttcgt aagccgtcat gattacaatc
      841 tcacatctga ctgctcagcc ggaagaacat acttcaaatc ataaagtaca tgtttatctt
      901 ttccgaagcc gcgaatatcc tcacttccca tctgtttaaa ttgctgatgt cctactgcaa
      961 caatgatcgc atcgtagtgg cttgatttga cttccgatac cgggataatg ccatactctc
     1021 gtcttacctc ttcggcatcc acccatggat caaaaatatc cactttacaa ctatatttac
     1081 cgagttcctt taccacatca ataatgcgtg tatttctgat gtccggacag ttttctttaa
     1141 aggtaaagcc gagaatcagc acgctggaac cctcaacgtt aattcctttt ttgatcattg
     1201 ctttgatcaa ctgctcggag acatagttgc ccatgttgtc gttcaggcgg cgtcctgcaa
     1261 gtatgatttc tggataatag ccaatgccct gagatttatg tgtcagataa tagggatcta
     1321 cgccaataca gtgaccaccg accagtcccg gacggaatgg caggaaattc catttgctgc
     1381 cagcggcacg tagcacggct tcagtatcga tatttaaacg attaaaaata atcgccagct
     1441 cattgaccaa ggcaatattc agatcgcgtt gcgtattttc aatcaccttc gctgcctcag
     1501 caactttgat gctctctgct ttatatgtac ctgcgctgat gatctgctga tatacttcat
     1561 cgataagttc ggcgatctgt gcggttgaac cggaggtgat tttcttgatg ttggttaaac
     1621 ggtgcttttt atcaccggga ttgatccttt ccgggctata accgacatag aaatcctggt
     1681 tgaaagtcat tccggacata cgagcaagga tcggcacgca ttcttcttcg gtacatcccg
     1741 gatataccgt agattcatat accacaatat ctccccgatt cagcactgta ccaacggttt
     1801 cactcgcctt gattagtggg gtgaggtctg gttgcttgta ggtatttatc ggcgtcggga
     1861 cggtgatgat gtaaaaatta cattctttga tcttctcaat ctcggaagta aatttcagat
     1921 aacgagcctc acgtaattct tcttcagtgg tttccagatt gacatccacc ccattcttta
     1981 attcaagaat acgcttttta ttaacgtcga agccaacaac ctgacgagat ttgccaaatt
     2041 caactgccag aggaagccca acatatccca gcccaataat cgcgatt
//
LOCUS       DAJVBX010000320         2084 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.321, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000320 DAJVBX010000000
VERSION     DAJVBX010000320.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2084)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2084)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2084
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.321"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            1..792
                     /gene="kdgR"
                     /locus_tag="OPV72_004379"
     CDS             1..792
                     /gene="kdgR"
                     /locus_tag="OPV72_004379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator KdgR"
                     /protein_id="HCR9916504.1"
                     /translation="MANADLDKQPDSVSSVLKVFGILQALGEEREIGITELSQRVMMS
                     KSTVYRFLQTMKTLGYVAQEGESEKYSLTLKLFELGARALQNVDLIRSADIQMRELSR
                     LTKETIHLGALDEDSIVYIHKIDSMYNLRMYSRIGRRNPLYSTAIGKVLLAWRDRDEV
                     KQILDGVEYKQSTGRTITSTEALLPLLDEVRAQGYGEDNEEQEEGLRCIGVPVFDRFG
                     VVIAGLSISFPTLRFSEERLQEYVAMLHVAARKISEQMGYNDYPF"
     gene            complement(1004..1243)
                     /locus_tag="OPV72_004380"
     CDS             complement(1004..1243)
                     /locus_tag="OPV72_004380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916505.1"
                     /translation="MRLIIRAIVLFALVWIGLLMSGYGILVGSKVNAAGLGLQCHYLT
                     ARGTSTAQYLHTNSGIIGFSDCPIFRKIATVVDNG"
     gene            1396..1539
                     /gene="mgrB"
                     /locus_tag="OPV72_004381"
     CDS             1396..1539
                     /gene="mgrB"
                     /locus_tag="OPV72_004381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoP/PhoQ regulator MgrB"
                     /protein_id="HCR9916506.1"
                     /translation="MKKFRWVVLGIVVVVCLLLWAQVFNIMCDQDVQFFSGICAINKF
                     IPW"
     gene            1610..1897
                     /locus_tag="OPV72_004382"
     CDS             1610..1897
                     /locus_tag="OPV72_004382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebO family protein"
                     /protein_id="HCR9916507.1"
                     /translation="MNDVLNSGAFSLASLIVSMVVLVVGLALWFFVNRASSRANEQIE
                     LLEALLDQQKRQNALLRRLCEANEPEKEAEPATAASEPKEDEDIIRLVAER"
BASE COUNT          557 a          443 c          520 g          564 t
ORIGIN      
        1 atggcaaacg cagatctgga taagcagcct gattctgtat cttctgtgct gaaagttttc
       61 ggcattctgc aggcgctggg tgaagagcgt gaaataggga ttaccgagct atcgcagcgc
      121 gtcatgatgt cgaaaagcac cgtttatcgc tttttgcaaa ccatgaaaac gctgggctac
      181 gtggctcagg agggggagtc tgaaaaatac tctctgacgc taaagctgtt tgagctgggc
      241 gcgcgagctt tgcaaaatgt tgatctcatc cgcagtgcgg acattcagat gcgcgaactg
      301 tctcgtctga caaaagaaac tatccatctt ggcgcgctgg atgaagacag cattgtctat
      361 atccataaaa ttgactctat gtacaatctg cggatgtact cacgtattgg gcgtcgtaat
      421 ccgctgtaca gtacggccat cggtaaagtg cttctggcct ggcgcgaccg tgatgaggtt
      481 aagcagattc tcgacggcgt agagtataag caaagcacgg gacgcacgat taccagcact
      541 gaagcgttgc tgccgctgtt ggatgaagtg cgtgcgcaag gctacggtga agataacgaa
      601 gaacaggaag aagggttacg ttgtatcggc gtaccggtat ttgaccgttt tggcgtagtc
      661 atcgcagggt taagcatttc gttcccgacg ctgcgttttt cagaagaacg cctacaggaa
      721 tatgtggcta tgttacacgt cgccgcgcgt aaaatttctg aacaaatggg ttacaacgat
      781 tatcccttct aagcaacgtt attagcatga cgttaaaaaa aagcagctac atttttcgta
      841 gctgcttttt ttataacatc gggtgggatg aaatcgtaaa agtagataat atctgtcggc
      901 ttatttaacg gttattaaaa tattatttaa cagtacttat gaacaacagc caatataggg
      961 gaattattgg tgatagtttc actgtgaaat tatttattgc cgcttagcca ttatccacca
     1021 cggtggcgat ttttctgaaa atgggacagt cggaaaagcc gataatgccg ctgttggtat
     1081 ggagatattg cgccgtgctg gtgccgcgtg cggtcaggta atggcactgt aaacccagcc
     1141 ccgcagcgtt cactttactt cccaccagga tgccatagcc gctcatcagc aggcctatcc
     1201 acaccagggc aaacaataca attgcgcgaa tgatcaaacg cattactacc tcttttttag
     1261 ttagaataag agtagcgtgt acattgattg aaacaagtga atcattccta aaaacatata
     1321 atgccgctac agttactcct ggtttaagta acttatgata atttagcgac ataagatgta
     1381 agatcggaga gtggagtgaa aaaatttcga tgggtcgttc tcggcatcgt ggtggtagta
     1441 tgcctgttgc tgtgggcgca ggtgtttaat atcatgtgcg atcaggatgt acaatttttc
     1501 agcggtattt gcgccatcaa taaatttatt ccctggtaaa cgttttacac cagagatttc
     1561 cttcccgtgt agcagtggta gaatgacgtc tctacattga ggtggtgaaa tgaacgacgt
     1621 tttaaactct ggtgcgtttt ctcttgcatc tttaatagta tcaatggtgg ttctggtggt
     1681 ggggctggcg ctctggttct ttgtcaaccg ggcaagttcc cgtgccaacg agcagataga
     1741 actgctcgaa gcgttgttgg atcaacagaa gcggcaaaac gcgttgttac gccgcctttg
     1801 cgaagcaaac gaaccagaaa aagaagcgga acccgcaaca gcggcaagcg aaccgaaaga
     1861 ggatgaggac atcattcgtc tggttgctga acgataatgc ttaccggggc gcaaatggcg
     1921 ccagtgccat acgccccatt tccccgtcgg atctctccgc gttgccgttt gcaactgata
     1981 ctacagcatc aacaccttac ctaatatatg gctttatatg caacatagtt ttatatgtat
     2041 aacaaatgga catatggcat ttttgtgata ccgctcattc tcta
//
LOCUS       DAJVBX010000321         2048 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.322, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000321 DAJVBX010000000
VERSION     DAJVBX010000321.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2048
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.322"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            87..1334
                     /locus_tag="OPV72_004383"
     CDS             87..1334
                     /locus_tag="OPV72_004383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001285496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase"
                     /protein_id="HCR9916508.1"
                     /translation="MSDNVIMQRNQIQKIRTGEDVLSAVTGRVEWIFDTFSQVCLSFS
                     GGKDSTVLFHIAATIARRKHRRFSVLFIDWEAQYQCTIEHVQKMKDLYSDVTETFFWV
                     ALPLTTVNGVSQFQPEWVCWEPDVEWVRQPPTDAITDTTYFPFYRYAMTFEEFVPAFS
                     TWFTGNQCGVAILTGVRADESLNRFIGLTSQRKLRYADDKPWTTASPEGFYYTMCPLY
                     DWKARDIWIYHARTGAIYNPLYDLMYRAGVPLRNMRVCEPFGPEQRRGLWLYHVLEPE
                     TWARMCARVSGAASGAIYANESGAYFALRKRISRPAHHTWRSYAMFLLDVMPQKTAEH
                     YRNKIAVYLRWYQTHGYPEDIPDEQENDLGSRDIPSWRRICKTLIKNDFWCRTLSFSP
                     NKPRHYERYLERMKQRRKEWGIL"
     gene            1319..1960
                     /locus_tag="OPV72_004384"
     CDS             1319..1960
                     /locus_tag="OPV72_004384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="HCR9916509.1"
                     /translation="MGDIVTREQVASLITRYFSQQLSDDEKVAALNHFRLTLHELSPF
                     AREPVDLVLWVKASEVVANDYNPNVMAAGEKKLLQHSLQEDGFTQPVVVSEEKGQYLV
                     VDGFHRQLLGRRESGAGKRLKGWLPVTCINPERKGKAERIASTIRHNRARGKHQIASM
                     SDIVRDLARLGWADERIGKELGMDRDEVLRLKQISGLTELFEEEDFSPAWTVR"
BASE COUNT          508 a          484 c          553 g          503 t
ORIGIN      
        1 tttaatattg tcatttcact aacaactgaa ctaatgctta gcagggtaat tattcaacat
       61 agcagggaga tggttttcag acactcatgt cagataacgt cattatgcaa cgtaatcaaa
      121 tacagaagat cagaaccggg gaggatgtgc tgtctgcggt tacaggccgt gtggagtgga
      181 tatttgatac cttttctcag gtttgtctgt ctttttcagg tggaaaagac tccaccgttc
      241 tgtttcatat cgccgccaca atagcccgca ggaaacaccg gcgtttctct gtccttttta
      301 ttgactggga agcccagtat cagtgcacga ttgagcatgt tcagaaaatg aaggatctct
      361 acagtgatgt gacggagacg tttttctggg tggctctccc gctgacgacg gtaaatggtg
      421 tttcacagtt tcagccagaa tgggtctgct gggagcccga tgtggagtgg gtgcgtcagc
      481 cgccgacaga tgccattact gatacgacgt attttccttt ttaccgttac gccatgacat
      541 ttgaagagtt tgtcccggca ttttcgactt ggttcacggg caatcagtgt ggagtggcca
      601 tactgactgg cgttcgtgca gatgagtccc ttaacaggtt tataggcctt accagccagc
      661 gaaagcttcg ttatgccgat gacaaaccct ggaccaccgc ctctcctgag gggttttatt
      721 acacgatgtg tcctctgtat gactggaaag cccgggacat ctggatttac catgcccgta
      781 cgggcgccat ttacaacccg ctgtatgacc tgatgtacag agccggcgtc cccctgcgga
      841 atatgcgggt ctgtgaacct tttggccccg aacagcgccg cggtctgtgg ctttatcatg
      901 tactggagcc tgagacctgg gcgcgaatgt gtgcccgcgt ctccggagcg gccagcgggg
      961 ccatttatgc taatgaaagt ggcgcttatt ttgccctgcg caaacgcatc tccagaccag
     1021 cacatcatac ctggcgcagc tatgccatgt ttcttcttga tgtcatgcca caaaaaacag
     1081 ccgagcatta ccggaacaag atagcggtat acctgcgctg gtatcagacg cacggttatc
     1141 cggaagatat tccggatgaa caggagaatg acctgggcag cagggatatt ccctcctggc
     1201 gtaggatatg caagacactg attaaaaatg acttctggtg ccggacctta tctttcagtc
     1261 ctaataagcc ccggcattac gaacgttacc tggagcgtat gaaacaaagg aggaaggaat
     1321 gggggatatt gtaaccaggg aacaggtggc cagtctcatt acccggtatt tcagtcagca
     1381 gctttcagat gacgaaaaag tggcagccct caatcatttt cgcctgacac ttcatgagct
     1441 cagccccttt gcccgggagc ctgtggacct ggtgctgtgg gtgaaagcca gcgaagtggt
     1501 ggccaacgat tacaacccca atgttatggc tgccggagag aaaaaattgc tgcagcactc
     1561 actgcaggag gacggcttta cccagcccgt cgttgtatct gaagagaaag ggcagtacct
     1621 ggtcgtggat ggttttcacc ggcagttgct gggcagacgc gagtcaggag caggaaaacg
     1681 cctgaaaggc tggttgcccg tcacctgtat caatcccgaa cgaaagggga aggctgaacg
     1741 aattgcctcg acgatcaggc ataaccgcgc ccgagggaag catcagatag cgtcgatgtc
     1801 agatattgtc agagaccttg cccgtctcgg atgggcagat gaacgtattg gcaaggagct
     1861 gggaatggac agggatgaag ttcttcgtct gaagcagata agtggactga cagaattatt
     1921 tgaagaagag gacttcagtc cggcctggac ggttcgctaa agtggacagc atcttatcgc
     1981 aaataaaact atttcggccg gtgacctgaa ttattattta atgattacca ataaagattt
     2041 ccgtataa
//
LOCUS       DAJVBX010000322         2008 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.323, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000322 DAJVBX010000000
VERSION     DAJVBX010000322.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 2008)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2008)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2008
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.323"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(105..1730)
                     /gene="prpR"
                     /locus_tag="OPV72_004385"
     CDS             complement(105..1730)
                     /gene="prpR"
                     /locus_tag="OPV72_004385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propionate catabolism operon regulatory protein
                     PrpR"
                     /protein_id="HCR9916510.1"
                     /translation="MTTAHSAPRDNSDKPVIWTVSVTRLFELFRDISLEFDHLATITP
                     IQLGFEKAVTYIRKKLATERCDAIIAAGSNGAYLKSRLSIPVILIKPSGFDVLQALAK
                     AGKLTSSIGIVTYQETIPTLLAFQKTFHLCLEQRSYVTEEDARGQINELKANGIEAVV
                     GAGLITDLAEEAGMTAIFIYSAATVRQAFHDALDMTRLTRRQRVDYPSGKGLQTRYEL
                     GDIRGQSPQMEQLRQTITLYARSRAAVLIQGETGTGKELAAQAIHQTFFHRQPHRQNK
                     PSPPFVAVNCGAITESLLEAELFGYEEGAFTGSRRGGRAGLFEIAHGGTLFLDEIGEM
                     PLPLQTRLLRVLEEKAVTRVGGHQPIPVDVRVISATHCDLDREIMQGRFRPDLFYRLS
                     ILRLTLPPLRERQADILPLAESFLKQSLAAMEIPFTESIRHGLTQCQPLLLAWGWPGN
                     IRELRNMMERLALFLSVDPAPTLDRQFMRQLLPELMVNTAELTPSTVDAHTLQDVLAR
                     FKGDKTAAARYLGISRTTLWRRLKAGAKDQSGN"
BASE COUNT          452 a          542 c          515 g          499 t
ORIGIN      
        1 tttccggcgg gtatttttat tcctggcaac cggcatccgt tttgccggat gacggcctgc
       61 agtaaacgta gcgccatcag gcattcagga cgctgtcatt tgtcttaatt acccgactgg
      121 tctttggcac ctgcttttaa acgacgccac agagtggtgc ggctaatccc cagataacgc
      181 gccgccgcgg tcttatcgcc cttaaagcgc gccagtacat cctgtaacgt gtgcgcatcc
      241 acggttgaag gcgtcagctc tgctgtgttc accataagct caggtaataa ctgccgcata
      301 aattgcctgt ccagcgttgg tgcgggatcg acgcttaaaa aaagcgccag gcgctccatc
      361 atattacgca gttcgcgaat attaccgggc cagccccagg ccagcaaaag cggctgacac
      421 tgtgtcaatc catgacgtat cgattcggta aacggaattt ccatcgccgc cagcgactgt
      481 tttaaaaagc tttccgccag cggcaaaata tcagcctgcc gctcgcgcaa aggaggaagc
      541 gtcagacgca gaatactcag gcgataaaag agatcggggc gaaaacgtcc ttgcattatc
      601 tcccgatcca gatcgcaatg cgtagcgctg atcacccgga catccaccgg gatcggttgg
      661 tgtccgccga cgcgagtgac ggctttttcc tccagtacgc gcaagagtcg ggtttgtaac
      721 ggcaagggca tttcgccgat ttcatccaga aacagcgtgc cgccgtgtgc gatttcaaac
      781 agccccgccc ggcctcctcg tcgtgaaccg gtaaacgcgc cctcttcata accaaacagt
      841 tccgcctcca gcaatgactc ggtaatcgcg ccgcaattga cggcgacaaa gggaggggat
      901 ggcttattct gacggtgagg ctggcggtga aaaaacgtct ggtgaatcgc ctgcgccgcc
      961 agctcttttc cggtccctgt ttccccctga atcagcactg ccgcacggga gcgggcatag
     1021 agcgtaatcg tctggcggag ctgctccatt tgcggcgact ggccgcgtat atcgcccagt
     1081 tcataccggg tttgtaatcc cttgccggat gggtaatcca cgcgctggcg ccgtgtcaga
     1141 cgggtcatat ccagcgcatc atgaaaagcc tgacgaacgg tcgccgcgga ataaataaag
     1201 atggcggtca tacccgcttc ttccgccaga tcggtaatta atcccgcgcc gacgacggcc
     1261 tcaataccgt tggccttaag ttcgttaatt tgcccgcgcg cgtcctcttc ggtgacatag
     1321 cttcgctgtt caagacagag gtgaaacgtt ttctgaaagg caagtaaagt cggaatggtc
     1381 tcctgatagg tcacgatacc gatagacgag gtgagctttc ccgctttcgc cagcgcctgt
     1441 aatacgtcga atccgctggg cttgatgagg atcaccggta ttgacaggcg actttttaaa
     1501 taggccccgt tcgaacccgc cgcgataatc gcgtcgcagc gctcggtcgc cagttttttg
     1561 cgaatgtagg tcaccgcctt ttcaaagccg agttgaatag gcgtgatggt cgccagatga
     1621 tcgaattcta ggctgatatc ccgaaacagt tcgaatagac gcgttacgga gaccgtccag
     1681 atcaccggtt tatcgctatt atcgcgcgga gcgctgtgag cagtcgtcat cgcagtaggt
     1741 tcatctttaa ggggcgattt tttgttttaa acgtgtttca taaatgttgc aatgaaacgg
     1801 agcgattcgt ttcatgaaac gttagctgac acgtttttct tttcccttaa tcgcgcttat
     1861 tcataacagg aatgactgta attacctgtt tttaaatctc attgtattta attttctcgc
     1921 tgcctctttg cctggcatag cctttgcttt ggtgaataca tcttgaataa caatttacta
     1981 acatgaggac gaattatgtc tttacatt
//
LOCUS       DAJVBX010000323         1983 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.324, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000323 DAJVBX010000000
VERSION     DAJVBX010000323.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1983
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.324"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            417..>1983
                     /gene="oppA"
                     /locus_tag="OPV72_004386"
     CDS             417..>1983
                     /gene="oppA"
                     /locus_tag="OPV72_004386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001675662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein OppA"
                     /protein_id="HCR9916511.1"
                     /translation="MSNITKKSLIAVGILTAFIAASAATAADVPAGVQLADKQTLVRN
                     NGSEVQSLDPHKIEGVPESNVSRDLFEGLLISDVEGHPSPGVAEKWENKDFKVWTFHL
                     RENAKWSDGTPVTAHDFVYSWQRLADPNTASPYASYLQYGHIVNIDDIIAGKKPATDL
                     GVKALDDHTFKVTLSEPVPYFYKLLVHPSVSPVPKSAVEKFGDKWTQPANIVTNGAYK
                     LKNWVVNERIVLERNPQYWDNDKTVINQVTYLPISSEVTDVNRYRSGEIDMTYNNMPI
                     ELFQKLKKEIPNEVRVDPYLCTYYYEINNQKAPFNDVRVRTALKLALDRDIIVNKVKN
                     QGDLPAYSYTPPYTDGAKLVEPEWFKWSQQKRNEEAKKLLAEAGFTADKPLTFDLLYN
                     TSDLHKKLAIAVASIWKKNLGVNVNLENQEWKTFLDTRHQGTFDVARAGWCADYNEPT
                     SFLNTMLSDSSNNTAHYKSPAFDKLIADTLKVADDTQRSELYAKAEQQLDKDSAIVPV
                     YYYVNARLVKPWVG"
BASE COUNT          586 a          438 c          473 g          486 t
ORIGIN      
        1 tatttttctt tcaacttatt gattataaag aataaatcaa agatttttaa cattctttaa
       61 ccgtttttct gggcaggcaa ttttccataa aagagaattg gttaacaaaa ttgtaaaatg
      121 aattggcggt tcagaaacgc atttgatact tttcggccaa acattttgca gaagatttca
      181 cattgttgat aactattttc atttacatgg ttgtcagaaa taacgtgcga cgtgggcagg
      241 tacgtcgtat accgaatcga cgaaagcgat cgaacgaatc gtcagaataa ataaagtcgg
      301 tgatagcaaa agcagtgaca gacctggcag tacaccacca gtgctgtaca ggagccctga
      361 cgggattaaa caggctggta aaaaccagta attataatga gtggagtaca aacacaatgt
      421 ctaacatcac gaaaaaaagt ttaattgcag tgggaatact cactgcgttc atcgccgcca
      481 gcgccgcgac tgcggcagac gtgcccgccg gtgttcagtt agccgacaag caaacgttgg
      541 tacgtaataa tggatcagaa gtgcagtctc tcgacccgca taaaattgaa ggcgtgccgg
      601 aatcgaacgt cagccgtgat ctctttgaag gcttattaat tagtgatgtc gaggggcatc
      661 cttcaccggg cgtcgcggaa aaatgggaaa ataaagattt taaagtctgg acattccatc
      721 tacgtgaaaa tgcgaaatgg tcagatggta cgcccgtcac cgcccatgat ttcgtttata
      781 gctggcaacg cctggccgat cctaatacgg catcgccgta cgccagctat ctgcaatacg
      841 gtcatatcgt taatatcgat gacattatcg ccggtaaaaa acccgccacc gatctggggg
      901 taaaagcgct tgatgatcac acctttaaag tgaccttaag tgagccggtg ccttatttct
      961 acaaattgtt ggtccaccct tcagtgtctc ctgtaccgaa atcagcggtc gaaaaatttg
     1021 gcgataaatg gacgcaacca gccaatattg tcactaacgg cgcttataag ttaaaaaatt
     1081 gggtggtgaa cgaacgtatc gtgctggagc gtaacccgca atactgggat aacgacaaaa
     1141 ccgtcatcaa tcaggtaact tatttgccta tctcttcgga ggtgacggat gttaaccgct
     1201 accgcagcgg cgagatcgat atgacttata acaatatgcc gatcgaatta ttccagaaac
     1261 tgaagaaaga gatcccgaat gaagtccgcg tagaccctta tttgtgtacc tattattacg
     1321 aaattaataa tcaaaaagcg ccgtttaacg atgtccgcgt gcgtaccgcg ctgaaactgg
     1381 cgttagatcg cgacattatt gttaataagg ttaaaaatca gggcgattta cccgcttata
     1441 gctacacgcc gccgtatacc gatggcgcaa aactggtaga gcctgagtgg ttcaaatggt
     1501 cccagcaaaa gcgtaatgaa gaagcgaaga aattgttggc tgaagccggc tttacggcgg
     1561 ataagccctt aacattcgac ctgctgtata acacctccga tctgcataaa aaactggcta
     1621 ttgccgtggc gtctatctgg aagaaaaatc tgggcgtcaa tgtgaatctg gagaatcagg
     1681 aatggaaaac cttcctggat acccgtcatc agggcacctt tgatgtcgcc agagccgggt
     1741 ggtgcgcaga ttataatgaa ccgacctcgt tcctgaatac catgttgtcc gacagttcaa
     1801 ataacaccgc gcattataag agcccggcgt ttgataagct gattgccgac acgctgaaag
     1861 tggcggacga tacgcagcgc agcgaactct acgctaaagc ggagcagcag ttagataaag
     1921 actcggctat tgtgccggtg tattactacg ttaacgcgcg cctggtgaaa ccctgggtgg
     1981 gcg
//
LOCUS       DAJVBX010000324         1981 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.325, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000324 DAJVBX010000000
VERSION     DAJVBX010000324.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1981)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1981)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1981
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.325"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            8..268
                     /locus_tag="OPV72_004387"
     CDS             8..268
                     /locus_tag="OPV72_004387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HCR9916512.1"
                     /translation="MKPDIHPVYRTVVFHDTSANEYVKVGSTIKTEREIELDGVTYPY
                     VTIDVSSKSHPFYTGRQKTFDSESSAARFQKRFGHFIGAKRG"
     gene            274..414
                     /gene="ykgO"
                     /locus_tag="OPV72_004388"
     CDS             274..414
                     /gene="ykgO"
                     /locus_tag="OPV72_004388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L36"
                     /protein_id="HCR9916513.1"
                     /translation="MQVLNSLRNAKQRHPDCQIVKRKGRLYVICKTNPRFKAVQGRKK
                     RR"
     gene            complement(470..940)
                     /locus_tag="OPV72_004389"
     CDS             complement(470..940)
                     /locus_tag="OPV72_004389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916514.1"
                     /translation="MTEIQRLLSETIDDLNVREKRDNRPRFSISFIRKHPGLFIAMYA
                     AWFATLAVMLQSETLVGSVWLLVVLFIAFNGFFFFDIAPRYHYNDIDVLDLRVCYNGE
                     WYNTRFVPPTLIETILQSPQVDNEHKVQLQKMVARKGELSFYDIFTLARAEASR"
     gene            complement(1058..1609)
                     /gene="maa"
                     /locus_tag="OPV72_004390"
     CDS             complement(1058..1609)
                     /gene="maa"
                     /locus_tag="OPV72_004390"
                     /EC_number="2.3.1.79"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose O-acetyltransferase"
                     /protein_id="HCR9916515.1"
                     /translation="MSDEKQKMIAGALYCPTDETLCQDRLRARQLIHQYNYTTPDEIN
                     KRQAILRDLLGRCEDAYIEPSFRCDYGYNIFLGHSFYANFDCVMLDVCPIHIGDNCML
                     APGVHIYTATHPLDAVERNSGRELGKPVTIGNNVWIGGRAVVNPGVTIGDNVVVASGA
                     VVTKNVPPDVVVGGNPARIIKKL"
     gene            complement(1788..>1981)
                     /gene="hha"
                     /locus_tag="OPV72_004391"
     CDS             complement(1788..>1981)
                     /gene="hha"
                     /locus_tag="OPV72_004391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hemolysin expression modulator Hha"
                     /protein_id="HCR9916516.1"
                     /translation="DYLMRLRRCQTIDTLERVIEKNKYELSDNELAVFYSAADHRLAE
                     LTMNKLYDKIPSSVWKFIR"
BASE COUNT          561 a          441 c          471 g          508 t
ORIGIN      
        1 gagcgcaatg aaacctgata ttcatcctgt ataccgaacc gtcgtatttc acgacaccag
       61 cgcaaatgaa tatgtgaaag tgggatcaac tatcaaaact gaacgtgaaa tcgaactgga
      121 cggcgtgaca tatccgtatg tcactattga tgtgtcatca aaatcgcatc ctttttatac
      181 cggtagacag aaaacgtttg atagcgaaag tagcgccgca cgcttccaga aacgttttgg
      241 tcattttatc ggcgctaaac gggggtaaat gaaatgcagg tgttaaactc acttcgcaat
      301 gcaaaacaac ggcatccgga ttgccagata gtcaaacgca aaggacgctt atacgtgatt
      361 tgtaaaacaa atccgcgttt taaggcggtt caggggcgta aaaaaagacg ttaaaaaacc
      421 aacagttcag ggaaagcagt gcgtaccagg gagggtgcgc acttttttat taccggctgg
      481 cttctgcgcg ggccagcgta aaaatatcgt agaaggaaag ttcgccctta cgggcaacca
      541 ttttttgcag ctggacttta tgttcattat ccacctgtgg agactgaaga atcgtctcaa
      601 tgagcgtggg gggaacaaag cgggtgttgt accattcgcc gttgtaacag acccggaggt
      661 ccagcacatc gatgtcgtta tagtgataac gcggggcgat gtcgaaaaag aagaagccat
      721 taaatgcgat aaataacacc actaacagcc acactgaccc caccagcgtt tctgattgca
      781 gcatgaccgc cagcgtcgca aaccaggctg catacatcgc gataaataac ccaggatgct
      841 tgcggataaa acttatacta aaacgcggcc tgttatcgcg tttttcacgg acgtttaagt
      901 catcaatagt ttcgctaagc aggcgctgta tctctgtcat cttttgcctt catgatttct
      961 gcgacatagg gggtagtaac agcccatttt aaagggaggt gtaacgtgaa aaaagtaaca
     1021 gattaaccac gaattagcat aacagttatc atttgaacta caatttttta atgattcgcg
     1081 ccggatttcc gcctaccacg acgtctggcg gtacgttttt tgtcaccaca gcgcctgaag
     1141 cgacgacgac gttatcgccg atggttacgc caggattaac gacggctcgt ccgcctatcc
     1201 agacgttatt tccgatagtg acgggtttac ctaattctct gccgctgttg cgttcgacgg
     1261 cgtccagcgg gtgcgtggcg gtatagatat gtacccctgg cgcgagcata caattatcgc
     1321 caatatgaat tgggcaaaca tcaagcatga cgcagtcgaa gttagcgtaa aaggagtgac
     1381 caagaaaaat attatagccg tagtcgcaac ggaaggaagg ttcaatatag gcgtcttcgc
     1441 atcgacccaa caggtcgcgt aaaatcgcct gacgcttatt tatttcatca ggcgtagtat
     1501 aattgtattg atggatgagt tgacgcgccc gcagtcgatc ctggcataaa gtttcatcgg
     1561 tcgggcaata cagtgcccca gcgatcattt tttgtttttc gtcactcatc gcgcgctccc
     1621 cttggtggat attatcgcaa tagaagcaat aataaagtat tagagggaac gttccctgct
     1681 attggtatgt gatctatatc actgttctat aatagcccgt tgtgttatta gccagaacga
     1741 ggaggcagat aacacctgcg tgttctctaa aaagtaatgt agcgtgatta acgaatgaat
     1801 ttccatactg aagaggggat cttgtcgtag agtttgttca tcgtcaattc tgcaagacgg
     1861 tgatccgcag ctgagtaaaa tacagccagc tcattgtcgg acaattcata tttatttttc
     1921 tcaatgacgc gctccagagt gtcaattgtc tgacagcgcc gtaaacgcat caaataatca
     1981 g
//
LOCUS       DAJVBX010000325         1977 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.326, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000325 DAJVBX010000000
VERSION     DAJVBX010000325.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1977)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1977)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1977
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.326"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..393
                     /gene="tnpA"
                     /locus_tag="OPV72_004392"
     CDS             <1..393
                     /gene="tnpA"
                     /locus_tag="OPV72_004392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HCR9916517.1"
                     /translation="KYRRQAFYGEKRRAVGSILRKLCEWKNVNILEAECCADHIHMLL
                     EIPPKMSVSGFMGYLKGKSSLMLYEQFGDLKFKYRNREFWCRGYYVDTVGKNTAKIQD
                     YIKHQLEEDKMGEQLSIPYPSSPFTGRK"
     gene            complement(501..839)
                     /gene="maoP"
                     /locus_tag="OPV72_004393"
     CDS             complement(501..839)
                     /gene="maoP"
                     /locus_tag="OPV72_004393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrodomain Ori organization protein MaoP"
                     /protein_id="HCR9916518.1"
                     /translation="MAESFTTTNRYFDNKHYPRGFSRHGDFTIKEAQLLERHGHAFND
                     LDLGKREPVTEEEKLFVAVCRGEREPVTDAERVWSKYMTRIKRPKRFHTLSGGKPQVE
                     GAEDYTEADD"
     gene            946..1794
                     /gene="hdfR"
                     /locus_tag="OPV72_004394"
     CDS             946..1794
                     /gene="hdfR"
                     /locus_tag="OPV72_004394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462788.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator HdfR"
                     /protein_id="HCR9916519.1"
                     /translation="MESTVDTELLKTFLEVSRTRHFGRAAEALYLTQSAVSFRIRQLE
                     NQLGVNLFTRHRNNIRLTTAGEKLLPYAETLMNTWQAARKEVAHTSRHNEFSIGASAS
                     LWECMLNAWLGRLYQLQEPQSGLQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEF
                     SSQLLGHFTLALYCSSPARKKSELNYLRLEWGPDFQQHETGLIAADEVPVLTTSSAEL
                     ARQQLSALNGCSWLPVNWANEKGGLHTVADSATLSRPLYAIWLQNSDKYSLICDLLKT
                     DVLDEQ"
     gene            complement(1896..1971)
                     /locus_tag="OPV72_004395"
     tRNA            complement(1896..1971)
                     /locus_tag="OPV72_004395"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1936..1938),aa:Trp,seq:cca)
BASE COUNT          558 a          453 c          504 g          462 t
ORIGIN      
        1 aaataccgaa gacaggcgtt ctacggagag aagcgtagag cggtaggcag cattttaagg
       61 aaactatgtg agtggaaaaa tgtgaacatt ctggaagcgg aatgctgtgc agatcatatc
      121 catatgcttc tggagatccc gccgaagatg agcgtgtcag ggtttatggg ttatctgaag
      181 ggaaaaagta gcctgatgct ttatgagcag tttggcgatt tgaaattcaa atacaggaac
      241 agggagttct ggtgcagagg gtactacgtc gatacggtgg gtaagaacac ggcgaagata
      301 caggattaca taaagcacca gcttgaagag gataaaatgg gtgagcagtt atcgatccct
      361 tatcctagca gcccgtttac gggccgtaag taacgaagtt tgatgcaaat gtcagatcgt
      421 atgcgcctgt tagggcgcgg ctggtaagag agccttacag gcgcatcaga aaaacctccg
      481 gctatgccgg aggatattta ttaatcatca gcttcggtgt agtcttctgc gccttcaact
      541 tgcggcttgc cgccagacaa ggtgtggaag cgttttggac gcttgatacg cgtcatatac
      601 ttggaccaga cgcgttctgc atccgttacc ggctcgcgtt caccgcgaca taccgctaca
      661 aacagcttct cttcttcagt cacaggctca cgcttgccaa gatccagatc attaaaggca
      721 tgaccatgac gctcaagcag ttgtgcctct ttaatcgtga aatcaccgtg acgagagaat
      781 ccacgtggat aatgtttatt gtcaaaatat cgattagtcg tcgtaaagct ttccgccatc
      841 ctgcacgctc ctaattcttt gtctgagcta tttatggcgc ggagtattag ttacgcttga
      901 cagagtgtaa aacaaaacat ttaaatcata acgacaaata attttgtgga gagcacagtg
      961 gatacggaat tgttaaaaac tttcctggaa gttagccgga cacgccattt cgggcgggcc
     1021 gcagaagcac tttacctgac gcaatccgcg gtgagctttc gtatcaggca actggagaat
     1081 caactgggcg taaacctttt tacgcggcac agaaacaata tccgtttaac cacggctggc
     1141 gaaaaacttt taccgtatgc ggaaacgctg atgaatacgt ggcaggcggc acgtaaagag
     1201 gtggcgcata cctcacgcca taacgagttt tccatcggcg ccagcgcgtc tttatgggag
     1261 tgtatgctta acgcctggct gggtcgactg taccaactac aggagccgca aagcggcctg
     1321 cagttcgaag ccagaatcgc tcaacggcaa tcgcttgtga agcaacttca tgaacgccag
     1381 cttgatctcc tcattactac cgaagcgccc aaaatggatg agttcagcag tcagctgtta
     1441 gggcacttca ctttggcgtt atattgcagc agccctgccc gtaagaaatc agaactcaat
     1501 tatctgcggc tggagtgggg accagacttc caacagcatg aaacagggct gatcgcagca
     1561 gatgaagtac cggtattaac aaccagctca gccgaactcg cccgacagca gcttagcgca
     1621 ttaaatggct gtagctggct tcctgtaaac tgggcaaatg aaaagggcgg attacatacc
     1681 gttgccgaca gcgcaacgct ttcacggccg ctatacgcca tttggctgca aaacagcgat
     1741 aaatactcgc tgatctgcga tctgttaaaa acggatgtgc tggatgaaca atgaaaatga
     1801 tgaaaagaaa aagaagggaa cttacgatta cctgatcaga taatcaggta atttcaggca
     1861 aaaaaaaatc cttagcagat gctaaggatt atttctggca ggggcggaga gactcgaact
     1921 cccaacaccc ggttttggag accggtgctc taccaattga actacgcccc taattag
//
LOCUS       DAJVBX010000326         1926 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.327, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000326 DAJVBX010000000
VERSION     DAJVBX010000326.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1926)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1926)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1926
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.327"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            78..836
                     /locus_tag="OPV72_004396"
     CDS             78..836
                     /locus_tag="OPV72_004396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001772481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HCR9916520.1"
                     /translation="MFPELFTIELFTLLKKWQERPISHLTLIDQFTDAYKQLFQQEAK
                     ERGQFIIAGSHLEQTGADRYENVAHIWGPDGEHYAHSKTHIFPAERGWYTQEGDKMAV
                     FQLPFAKVGFNICYEAEIPECAATLAEQGAELILTPSATFTEQGFWRVRHCCHARCIE
                     NQIYLVHCCLGGNPGGPLPGCWARSSILSPCDVVWKNPQGIIAEAHVNQEDVISGEIN
                     LDVLYENRLGGAATTFKDRRRKAGIYNIWPSHIK"
     gene            875..1798
                     /locus_tag="OPV72_004397"
     CDS             875..1798
                     /locus_tag="OPV72_004397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HCR9916521.1"
                     /translation="MGYLKLPEGKRIAVNLGVDVDAQSLWLGGFNRPSPSFMSRGEFG
                     AQVGVPRLLKLFKENNIKTTFFIPGHTVDTFPEISKAIFDAGHEIAHHGYYHENPTLV
                     NRDTERRLMDLAFACYKRHFGIRPVGYRSPYWDYSENTLDLLEEAGFLYDSSLMARDL
                     VPYHPQRWQVNWETGNIAGPASAILEIPVSWYLDDFPALAYTGNQEGMSDTDGVLRRW
                     KDIFTYAYNHQENGLYAMALHPQIIGHGHHMMMLSRLIEHIKGHDGVWFATCEEIASV
                     WVDDEEDRQKMLRPDVRGVAPVPDDYGWPGK"
BASE COUNT          525 a          390 c          491 g          520 t
ORIGIN      
        1 ctgaaataaa cacttttgaa gatttcataa caaaggtaag gatacttctt aataaaagtc
       61 agggggctga tgccgttatc ttcccggagc tatttaccat tgagctattt acactattga
      121 aaaaatggca agaaagaccc atttcacacc taactttaat tgatcagttt acggatgcct
      181 ataagcagct ttttcaacag gaagcgaaag aaagaggaca gttcattatt gctggctctc
      241 atctggagca gactggagca gatcgctatg agaatgttgc gcatatatgg ggacccgatg
      301 gcgaacatta tgctcacagt aagacgcata tcttcccggc tgaacggggt tggtatactc
      361 aggaaggcga taaaatggct gtttttcaac tgccatttgc aaaggtgggt tttaatattt
      421 gttatgaagc agaaataccg gagtgtgctg cgacgctggc ggaacagggt gctgagttaa
      481 ttttaacgcc ttccgctacg tttactgaac agggattttg gcgagtcagg cattgttgcc
      541 acgcacgttg tattgaaaat caaatttatc ttgttcactg ttgcctggga ggaaacccgg
      601 gcgggccact gccaggctgc tgggcccgaa gttcaatttt aagcccctgt gatgtcgtgt
      661 ggaaaaatcc acaaggtatt atcgcagagg cgcacgtcaa tcaagaggat gtcatttcag
      721 gagaaattaa cctcgatgtt ctatatgaaa atagacttgg gggggcagca acaacgttca
      781 aggacagacg cagaaaagca ggcatatata atatctggcc atcacacatt aaataacaga
      841 atgtgtccct tctatgtatt agctggaggt cgttatggga tatttaaaat tacctgaggg
      901 taaaaggatt gcggtcaatc ttggtgtcga tgtagatgct cagtctttat ggctgggcgg
      961 atttaatcga ccgtcgccat cctttatgtc acgaggagag tttggcgcac aagttggcgt
     1021 tccaaggctt ctgaaattgt tcaaagaaaa taatatcaaa accacctttt ttattcccgg
     1081 acacactgta gacaccttcc cggaaatcag taaagcgatt tttgatgccg ggcatgaaat
     1141 cgctcaccat ggctactatc atgaaaaccc gacgctggtg aatcgtgata cagaacgccg
     1201 acttatggat ctggcgttcg cctgttataa aagacatttt ggcatacgcc ctgtgggata
     1261 ccgttctccc tattgggatt atagcgagaa tacgctggat cttctggagg aagccggttt
     1321 tctctatgac agtagcctga tggcgagaga tcttgtgcct taccatcctc aacgttggca
     1381 ggtgaattgg gaaacgggaa atatcgcagg cccggccagc gcgattctgg aaattcctgt
     1441 tagctggtat ctggatgatt ttcccgcact ggcgtatacc ggtaaccagg aggggatgag
     1501 cgatactgac ggtgttctgc gacgctggaa ggatattttt acctatgctt ataaccatca
     1561 ggaaaacggt ttatatgcga tggctcttca tccgcagata atcggtcatg ggcatcatat
     1621 gatgatgttg tcacgtttga ttgaacatat taaagggcat gatggcgtat ggtttgcaac
     1681 ctgtgaagag atagccagtg tctgggtgga tgacgaagag gatcgacaaa aaatgctccg
     1741 tcctgatgtt cgtggcgtag cgccggttcc ggatgattat ggctggccag gcaaatgata
     1801 tcacctcatg acaatgttaa tatcagtcgg gtaacggatt acccgggcag aagttacctg
     1861 tttgcccgct tgttaatgca tattgtccat cagaaaggga gactatcccg ggacgtataa
     1921 aatctt
//
LOCUS       DAJVBX010000327         1902 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.328, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000327 DAJVBX010000000
VERSION     DAJVBX010000327.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1902
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.328"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..654
                     /locus_tag="OPV72_004398"
     CDS             <1..654
                     /locus_tag="OPV72_004398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000954687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosylmethionine:tRNA
                     ribosyltransferase-isomerase"
                     /protein_id="HCR9916522.1"
                     /translation="EALICYLASHGERLDEYVDSSLFYKYPDAYRSVFSKKYGSLEIP
                     SAGIHFTWDLIQKIKDKGGLISFITLHVASTEMLSNRKIQTKCVEEVTINEEYYEVPQ
                     ATADIINTAKQNGGRIFAVGTTVTRCLESAYSREHNCLKASSGWTALYIHPGYQLKVV
                     DCLLTNLHQPKTTHMVLTGQFAGVDLLMKAYASEDIQSCQFDMFGDCMLIIQDEGQG"
     gene            complement(706..828)
                     /locus_tag="OPV72_004399"
                     /pseudo
     CDS             complement(706..828)
                     /locus_tag="OPV72_004399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418669.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
     gene            complement(822..950)
                     /locus_tag="OPV72_004400"
                     /pseudo
     CDS             complement(822..950)
                     /locus_tag="OPV72_004400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460510.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system mRNA interferase
                     toxin, RelE/StbE family"
     gene            1104..1295
                     /locus_tag="OPV72_004401"
                     /pseudo
     CDS             1104..1295
                     /locus_tag="OPV72_004401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002211098.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1296..1403
                     /locus_tag="OPV72_004402"
                     /pseudo
     CDS             1296..1403
                     /locus_tag="OPV72_004402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1493 family protein"
     gene            complement(1518..>1902)
                     /locus_tag="OPV72_004403"
     CDS             complement(1518..>1902)
                     /locus_tag="OPV72_004403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001681585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916523.1"
                     /translation="IYAQRSTQLSATLLGIDPVIYSNHMFLHEWTTEQLVKDYGKLNP
                     LSSEEQAITMGLSAAEVKFLTALSDLELKKIRERGQLESLRHELRISRHDLQGKRVQD
                     KRVQINRIRAASRQGRDQTYGPEVF"
BASE COUNT          528 a          399 c          410 g          565 t
ORIGIN      
        1 gaggctttaa tttgctattt agccagtcat ggtgagcgtc ttgatgagta tgtggactcc
       61 agcttgtttt ataaatatcc agatgcttac cgttccgttt tttctaaaaa gtatggctct
      121 ttggaaatac cttctgccgg cattcatttt acctgggatc ttatccaaaa aatcaaagat
      181 aaaggtgggt taatatcttt tattacttta catgttgcat caacagaaat gttgtccaac
      241 agaaaaatac aaacaaaatg tgtagaggaa gtgactatca acgaagaata ctacgaggtt
      301 ccacaagcta cagcggatat cattaatact gcgaagcaaa atggcggacg tatttttgcc
      361 gtaggaacta ccgttacacg atgcctggag tccgcgtatt cgagggaaca caattgcctc
      421 aaagcaagtt ctggctggac tgcgctttat atacatccag gctatcaact gaaagtggtt
      481 gactgcctgc taacgaactt acatcagcca aaaacgacgc atatggtgtt aactggtcag
      541 tttgctgggg ttgatctact catgaaggcc tatgcctcag aagatatcca gtcatgtcag
      601 ttcgatatgt ttggtgattg catgttaatc atacaggatg aagggcaggg atgaataaaa
      661 taaaaccggt acacataatg ctaccggttt taccgagaat aagcatcagg ggattcgggc
      721 aataaccttt atttcgaaat caaagccggc cagccaggta acgccaacag cggtccagtt
      781 aggataaggg ggataggcaa atatctcctg tttcaccgcc atcacgtcgt taagttgtag
      841 acggcatcat tttcacgctt tccaacacca atgacagtta ccgtgataat ttcatcttcg
      901 acgctgtaga ccagtctgta tcctgcacca cacggcttaa ttttgtactt aactgcttgt
      961 atcgattacc aggaacgtta acagcgtgcg caccagcttg ccattgtcta attcaagcac
     1021 acgacgaaca aatgtgttat aacaatccta taaagtggtt gcattgccaa tgcataaagt
     1081 taatttaatc aggaaattag agtatggata cagttgaaga gcttaatagc acttattttt
     1141 atgccggacg ttcaaatctg actgctagtc agttgctgtt tatgattttc tgcgaaaaca
     1201 ctgccaatca gttgggtgtt caggattttg gggcgatagt gtctattgtg gctggattga
     1261 atgttttgcc tacgcggaca aaaccgcgtg gtgctaagca tttgcttaat ccgtttcgca
     1321 aaaacgatat tcctcaggcg ccggagttca cgataggtat gctcattgcg tctgccaggg
     1381 ctggtcgctg gttgtatgac tgattcacgc ttgggggctg ctttccgttc tccatcatca
     1441 tggagcgcat aatgtatatt atgttaaatg caccagaaca attaaaagac atgttaaggc
     1501 ggctggattc gtgcatgtca aaaaacttct ggcccataag tttgatccct tccctgccgt
     1561 gacgctgcgc gaattctgtt gatttgcacc cgcttatcct gcacacgttt tccttgcaag
     1621 tcatgccttg agattcttag ttcatgcctt aaggattcca gttgacctct ttctctaatc
     1681 ttttttaatt ccagatcgga aagcgcagta aggaatttta cttccgcggc tgatagtccc
     1741 attgtaatcg cttgctcttc agaagaaaga ggatttaatt taccataatc cttgaccaac
     1801 tgctccgtag tccattcatg taaaaacata tggttactat aaataaccgg atcaatacct
     1861 aatagtgttg ccgataattg agttgatcgc tgtgcataaa tt
//
LOCUS       DAJVBX010000328         1805 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.330, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000328 DAJVBX010000000
VERSION     DAJVBX010000328.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1805
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.330"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            73..1125
                     /gene="pipB2"
                     /locus_tag="OPV72_004404"
     CDS             73..1125
                     /gene="pipB2"
                     /locus_tag="OPV72_004404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system effector PipB2"
                     /protein_id="HCR9916524.1"
                     /translation="MQRSLDSLAGMATSAFGAGTSAAMRQATSPKTILQHIINFFTCG
                     GIRRRNETQYQELIETMAETLKSSMSDRGAPLPENIILDDVDGCRVEFNLPGENNEAG
                     QVIVRVSKGDNSETREIPLASFEKICRALLFRCEFSLPQDSVILTAQGGMNLKGAVLT
                     GANLTAENLCDADLSGADLEGAILFMADCDGANFKGANLSGASLGDSNLTNACLEDSI
                     MCGATLDRANLTGANLQHTSLLGCSMVECNCSGANMDHANVSGSTLIRADMSGATLKG
                     ATIMAAIMEGAVLTRANLQKASFTATNLDGADLSEANLRNTSFKDCTLTDLRTEDATM
                     STSTQTLFNVFYSENI"
     gene            1300..1633
                     /locus_tag="OPV72_004405"
                     /pseudo
     CDS             1300..1633
                     /locus_tag="OPV72_004405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_449164.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          525 a          367 c          409 g          504 t
ORIGIN      
        1 accttatttc taaatgcaaa tctaatgata aattttatca tgtactgtgt tgctctctct
       61 gggagaaaat atatgcagcg ttcactcgat agtctggctg gtatggctac atctgctttt
      121 ggcgcgggga cttctgctgc tatgcggcaa gctacctcgc ccaaaaccat tctgcaacat
      181 atcattaact tttttacctg tggtgggata cgtcggagaa atgaaacaca atatcaggaa
      241 ttgatagaga ctatggctga aacattgaaa agttcaatgt ctgacagagg tgctccgttg
      301 ccagaaaaca tcatcctgga tgatgtggat gggtgtcgtg tcgaatttaa tcttcctggt
      361 gagaataacg aagctggaca agttattgta cgagtcagta aaggcgacaa ttctgagaca
      421 agagaaattc cgcttgcctc ttttgaaaaa atatgtcgag ctttactatt cagatgcgaa
      481 ttttctcttc ctcaggattc tgtaatatta actgcccagg gaggcatgaa tcttaaaggc
      541 gctgtcctta ccggagcaaa tctgacggca gaaaatttat gtgacgcaga cttaagcggc
      601 gcagatttag agggggcaat actgtttatg gcggattgtg acggtgcaaa ttttaagggc
      661 gcaaatctat cgggagcatc attaggcgac agtaacttaa cgaacgcctg tctggaagat
      721 agtattatgt gtggcgctac cctcgatcgc gctaatctta ctggcgccaa tttacaacac
      781 acaagtctgt taggctgtag catggtagaa tgtaattgtt ccggtgcgaa tatggatcac
      841 gctaatgttt caggctcaac ccttatacgt gccgatatga gcggtgcgac attaaagggt
      901 gctactataa tggctgctat tatggaaggc gctgtcttaa ctcgggcaaa cctgcaaaag
      961 gctagtttta ctgctacgaa cctggacggg gctgatttgt ctgaggctaa tttaagaaat
     1021 accagtttta aagattgtac actaaccgat ttgcgtaccg aagacgccac aatgtctaca
     1081 agtacacaaa cactttttaa cgtattttat agtgaaaata tttagcccta tttgacgtaa
     1141 atctgaaata aaagcaatgt aagaataaca atctgctact gaatagtagc tgagagttaa
     1201 ttatttacag tatcttttat tattacagga gtatgcgccg gtaaaaatat ctgaataacc
     1261 atttctattt tctcaagtag aacttccaac taaagcgaat tgtttgaaaa ggaaaacgtt
     1321 atgcctggat gtataagtgc ctgttcgtgc gttgccagcc cgacgcctcc cgatcctaag
     1381 gcccccccct aagcctaagt ggatagagtt aaaaggttat tgtgttacat gtactagtca
     1441 ggaggatatt cgtccaccta aagagggtga accaaagcaa aaaatgacac ccagcgagtt
     1501 agtgctgtta cgaggtcttt taaaagacct gggggtaaca caacatccct ggcaagaccc
     1561 gacagtaaaa tccactaact gtgggttgcc atattttcca gtagatcctg gagaacgaga
     1621 aaccgatgtt tgatggtttt ctgtctgcaa agcgcctgat aattattacc aggcgctttg
     1681 tattttggcg ccaacatcac tttcattgtc atatatcgaa tgactacaat cgtatccgat
     1741 cccgccatta ccctgacggc aaactgtaag aacggtttgc cgtcgacagg gaagcgccgg
     1801 tgaac
//
LOCUS       DAJVBX010000329         1796 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.331, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000329 DAJVBX010000000
VERSION     DAJVBX010000329.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1796
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.331"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            341..781
                     /locus_tag="OPV72_004406"
     CDS             341..781
                     /locus_tag="OPV72_004406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001748181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HCR9916525.1"
                     /translation="MQKYIFSADKNAFFPVELKIAYQESGEWPDDGIEIDDTVAAEFM
                     KEAPEGKYRGVIDGMPAWIDIPPPTHEEQIAAAELEKQQLINQVNEYINSKQWPGKAA
                     IGRLKGEELAQYNLWLDYLDALELVDTSGAPDIEWPTPPAVQAR"
     gene            complement(753..1346)
                     /locus_tag="OPV72_004407"
     CDS             complement(753..1346)
                     /locus_tag="OPV72_004407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HCR9916526.1"
                     /translation="MKPVFDENGLATVPGDMRCYYYDAVTSEYTGWSDEYINTGVSMP
                     ACSTGIDPGEYIPGRVAVFTGKGWSHEEDHRNETVYSTENGAAVTVDYIGAIKDGYVT
                     LSPLTPYDKWDGEKWVTDTEAQHSAAVEAAEAQRQSLIDAAMASISLIQLKLQAGRKL
                     TQPENTRLNAVLDYIDAVTATDTSTAPDVIWPELPEA"
     gene            complement(1346..1777)
                     /locus_tag="OPV72_004408"
     CDS             complement(1346..1777)
                     /locus_tag="OPV72_004408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001143952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber protein"
                     /protein_id="HCR9916527.1"
                     /translation="MPVPWPSATPPTGWLKCNGAAFSAEEYPELAKVYPTNKLPDLRG
                     EFIRGWDDGRGVDAGRQLLSSQGDAIRNIEGFADGGIGMSFDAIRGAFYDAGTRSARM
                     PNNTTDIGKTDDLGFDASRVVPTANENRPRNIAFNYIVRAA"
BASE COUNT          465 a          446 c          416 g          469 t
ORIGIN      
        1 aacggaatgt gggcacagga gataatcaga taccggatat gggagcattc gcttctggtt
       61 cgggatggtt caggctacca ggtggatata ttgttcagtt tggcactttt tcaggaaaca
      121 cgacccgctt tatcagtgga cacttcccta taccattccc taatcagccg atggtttcag
      181 tcagtgttat gtctgataac gttcagtcag acccgtcgat tcctgctccg caggttttgt
      241 ctgtaaattt tgaacatatc agtaattcag cgtggcgtgt ggcaaccagt gatatctcac
      301 agcaatacag attcagttat atttcgatag gacggtagaa atgcagaaat atattttcag
      361 cgccgataaa aatgcgtttt tccctgtgga gcttaaaatc gcttatcagg aatccggcga
      421 atggcccgat gatggaatcg aaattgacga cactgttgcc gccgaattta tgaaggaagc
      481 accagaagga aaatacagag gtgtcatcga cggaatgcct gcatggattg atattccacc
      541 gccaactcat gaggaacaaa ttgccgcagc cgaactggaa aagcagcaat tgattaatca
      601 ggtcaacgaa tacataaaca gtaagcaatg gcctggtaaa gcggcgattg gtcgcctgaa
      661 aggtgaggaa ctggcgcaat ataatttgtg gctggattat ctggacgcac tggaactggt
      721 cgatacttcc ggtgcgccag atattgaatg gcctacgcct ccggcagttc aggccagatg
      781 acgtccggcg ctgtgctggt atctgttgcc gttaccgcgt caatataatc cagcacagcg
      841 ttaagtcggg tgttttctgg ctgcgtcagc ttccgcccgg cctgtaattt cagttgaatc
      901 agactgatgg aagccattgc agcatcaatc agcgactggc gctgtgcttc tgcagcttct
      961 actgcggcgc tatgctgtgc ctcggtatcc gtcacccatt tctcaccatc ccatttatcg
     1021 tatggcgtta acggtgaaag cgtgacataa ccgtctttga tggcaccgat ataatccact
     1081 gtaacagctg cgccattttc agttgagtaa acggtctcat tgcgatggtc ttcttcatgg
     1141 ctccatccct tacccgtaaa tactgccact cttcccggaa tgtattcgcc cgggtcaata
     1201 ccagtggaac aagcgggcat acttacgcca gtattaatat attcatcaga ccagcccgta
     1261 tattcagacg ttactgcatc ataataataa caacgcatat cacccggcac tgtagccagc
     1321 ccattttcat caaaaacagg tttcattatg cagccctcac aatataatta aaggcgatgt
     1381 tacgtggacg gttttcatta gctgttggca cgacacgaga ggcgtcgaat ccaaggtcat
     1441 cggttttgcc tatatcagtt gtgttattcg gcattctcgc agatcgtgtt cctgcatcat
     1501 aaaaagcccc tctgattgca tcaaaagaca taccgatccc gccatctgcg aatccctcaa
     1561 tatttcttat tgcatccccc tgtgaagata ataattgtcg cccggcatcc actccacgtc
     1621 cgtcatccca gccacgaata aattcaccgc gtaaatcagg caatttattt gtcgggtaaa
     1681 cctttgccag ttccgggtat tcttcagcag aaaaagccgc accattgcat ttcagccagc
     1741 ctgttggcgg agtggcggaa ggccacggaa caggcacacc aacgggtaat gccgaa
//
LOCUS       DAJVBX010000330         1730 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.332, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000330 DAJVBX010000000
VERSION     DAJVBX010000330.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1730)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1730)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1730
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.332"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(102..1031)
                     /gene="metA"
                     /locus_tag="OPV72_004409"
     CDS             complement(102..1031)
                     /gene="metA"
                     /locus_tag="OPV72_004409"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HCR9916528.1"
                     /translation="MPIRVLDELPAVNFLREENVFVMTTSRASGQEIRPLKVLILNLM
                     PKKIETENQFLRLLSNSPLQVDIQLLRIDARESRNTPAEHLNNFYCNFDDICDQNFDG
                     LIVTGAPLGLVEFNDVAYWPQIRQVLEWAKDHVTSTLFVCWAVQAALNILYGIPKQTR
                     TDKLSGVYEHHILHPHALLTRGFDDSFLAPHSRYADFPAALIRDYTDLEILAETEEGD
                     AYLFASKDKRIAFVTGHPEYDAHTLAGEYFRDVEAGLNPEIPYNYFPKNDPQSIPRTT
                     WRSHGNLLFTNWLNYYVYQITPYDLRHMNPTLD"
     gene            1188..1625
                     /locus_tag="OPV72_004410"
     CDS             1188..1625
                     /locus_tag="OPV72_004410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HCR9916529.1"
                     /translation="MMINIRRSRREEGEKLIAIWRRSVDATHDFLSNAYRAELEELVS
                     DFLPEAPLWVAVTDQDEPVGFMLLTGEHMDALFIDPDVRGQGIGKMLVEHALTLAPGL
                     TTNVNEQNTQAVGFYKKMGFKVTGRSEVDDLGKPYPLLNLIYP"
BASE COUNT          471 a          378 c          455 g          426 t
ORIGIN      
        1 aatttaatta catgatgagg tgcgtttcgg aaataaaaaa ggcacccgaa ggtgcctgat
       61 tcaacatgct gaaacgcttt aggattgtca gaagcagaag attaatccag ggttggattc
      121 atgtgacgca gatcatatgg cgtaatctgg tagacataat agttgagcca gttagtaaac
      181 agtaaattgc cgtggctgcg ccaggttgtg cgcggtatgc tttgcggatc gtttttcggg
      241 aaatagttgt acggaatctc cggatttaac ccggcctcaa cgtcacgaaa atattccccc
      301 gctaacgtat gagcgtcata ttcaggatga ccggtgacaa acgcaatacg tttatctttg
      361 ctggcaaaca ggtacgcatc cccttcttct gtttcggcca gaatttcaag atccgtataa
      421 tcccgtatta gcgccgccgg gaaatcggca tagcgtgagt gtggcgcaag aaacgaatca
      481 tcaaaaccac gcgttaacag agcatgtgga tgaagaatgt gatgttcata gacgccggaa
      541 agtttatctg tacgggtctg cttagggata ccataaagaa tattgagtgc ggcctgaacg
      601 gcccaacaga caaatagcgt cgaagtaacg tgatctttcg cccattccag cacctgccta
      661 atctgcggcc agtaagccac gtcattaaac tccaccagac ccagcggcgc tccggtcacg
      721 ataagcccat caaagttctg atcgcagata tcgtcgaagt tacagtaaaa gttgttcaga
      781 tgctcggctg gcgtgttcct cgactcgcgg gcatctatcc gcagtagttg aatatcgacc
      841 tgcaatggcg agttcgatag caaacgcaga aactgatttt ccgtttcaat cttcttcggc
      901 atcaggttaa ggataagtac ctttagcggg cgaatttcct gacctgatgc gcgagaagtc
      961 gtcatgacga agacattctc ctcacgtaaa aaattgacgg cgggtagctc gtccagcacg
     1021 cgaatcggca taacctgata acctcacgat atacgtttaa acgtttagac atccagatag
     1081 ctgaagatac tcagaaatca ggcgaatgtc gagtctgcaa gttcaaggtg agaaagtttc
     1141 acgacagcat ttgcattaga atagaagtaa gcaaaaaagg agtgaagatg atgattaaca
     1201 ttcgtcgttc aaggcgtgag gaaggggaaa aactgattgc gatctggcgt cgctcagtcg
     1261 atgccacgca cgattttctg tcaaacgctt atcgggccga actggaagaa ctggtgagcg
     1321 attttctgcc agaagcgcca ctatgggttg ccgtgaccga tcaggatgag ccggtagggt
     1381 ttatgctgct taccggtgag catatggatg ctctgtttat cgatccggac gtgcgtggtc
     1441 agggtatcgg taagatgctg gttgaacatg cgttaacact ggcgccggga ttgacaacca
     1501 atgttaacga gcaaaataca caagctgttg gattttataa gaaaatggga ttcaaggtga
     1561 cgggacgttc ggaggtcgac gatcttggga aaccgtatcc attgttgaat ttaatttatc
     1621 cgtgagtagt ggcgctgcct gataagtgca tgcaggccgg ataaggcgaa gccgccatcc
     1681 ggcggtgcag gttgcctgat ggcgctgcgc ttatcaggcc tacattttta
//
LOCUS       DAJVBX010000331         1725 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.333, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000331 DAJVBX010000000
VERSION     DAJVBX010000331.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1725)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1725)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1725
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.333"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..935
                     /locus_tag="OPV72_004411"
     CDS             <1..935
                     /locus_tag="OPV72_004411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCR9916530.1"
                     /translation="LFQKWARLDPLPYSQRILNIRDKVTTQEDSVIVIHNSMKLYRQI
                     RERNPNAKLVMHMHNAFEPELPDTDAKIIVPSQFLKAFYEERLPAAAVSIVPNGFCAE
                     TYKRNPQDNLRQQLNIAEDATVLLYAGRISPDKGILLLLQAFKQLRTLRSNIKLVVVG
                     DPYASRKGEKAEYQKKVLDAAKEIGTDCIMAGGQSPDQMHNFYHIADLVIVPSQVEEA
                     FCMVAVEAMAAGKAVLASKKGGISEFVLDGITGYHLAEPMSSDSIINDINRALADKER
                     HQIAEKAKSLVFSKYSWENVAQRFEEQMKSWFDK"
     gene            complement(992..>1725)
                     /gene="rfaL"
                     /locus_tag="OPV72_004412"
     CDS             complement(992..>1725)
                     /gene="rfaL"
                     /locus_tag="OPV72_004412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="O-antigen ligase RfaL"
                     /protein_id="HCR9916531.1"
                     /translation="HRHMSDSMVFLFPALLNIWLFRKNSIKLVFLVLSAIYLFFILGT
                     LSRGGWLAVLIVGVLWAILNRQWKLIGVGAILLAIIGALVITQHTNKPDPEHLLYKLQ
                     QTDSSYRYTNGTQGTAWILIQENPIKGYGYGNDVYDSVYNKRVVDYPTWTFKESIGPH
                     NTILYIWFSAGILGLASLAYLYGAIIRETASSTFRKVEISPYNAHLLLFLSFVGFYIV
                     RGNFEQVDIAQIGIITGFLLALRNR"
BASE COUNT          539 a          354 c          378 g          454 t
ORIGIN      
        1 gtctttttca gaaatgggct cgtctcgacc cactacccta ttcccagcgc atccttaata
       61 ttagagataa agtgactacc caggaagata gcgtcattgt tattcataat agtatgaaac
      121 tgtatcggca gatcagagag cgcaatccga atgcaaaact ggttatgcac atgcataacg
      181 catttgaacc agaacttcct gatacggatg caaaaattat cgtgcccagt cagtttctta
      241 aagcgtttta tgaagaaaga ttgcccgccg ctgctgttag tattgtgcct aatggttttt
      301 gtgctgagac ttataaaaga aacccacaag ataatcttcg tcagcaatta aatattgcgg
      361 aagatgccac cgttctctta tatgccggga gaatttcgcc tgataaaggc atcctgttgc
      421 ttttgcaggc gttcaaacaa ttacgtacct taagaagtaa tattaaactt gtcgttgttg
      481 gcgaccctta tgcaagccgc aagggtgaaa aagcagagta tcaaaagaaa gtactggacg
      541 ccgcaaaaga gattggaact gattgcatta tggctggagg gcaatcacct gaccagatgc
      601 ataacttcta tcatatagcc gatctggtta tcgtgccatc tcaggttgaa gaagcatttt
      661 gcatggtggc tgtagaagcg atggcagcag gaaaagcggt tcttgccagc aaaaaagggg
      721 ggattagcga atttgtgtta gatggcataa cgggctatca cctcgcagaa cctatgtcga
      781 gcgacagtat aattaatgat attaaccgtg cgcttgctga taaggaacgc caccagattg
      841 ccgaaaaagc aaaatccctg gtgttttcaa aatacagttg ggaaaatgta gcgcagcgtt
      901 tcgaggaaca aatgaaaagc tggtttgata agtgattgag tcctgatgat ggaaaacgcg
      961 ctgataccgt aataagtatc agcgcgcttt tttatctatt tcttagcgcc agcagaaaac
     1021 cggtaatgat accaatttga gcaatatcga cctgttcaaa attgccacga acgatataaa
     1081 aaccgacgaa agataaaaat agcaagagat gagcattgta ggggcttatc tctactttcc
     1141 tgaaggtaga gctggctgtt tccctgatga tagcgccata taaataggcc aggctcgcca
     1201 gacccaatat gcctgcacta aaccagatgt acagaatggt attatgcgga ccgatagatt
     1261 ctttaaaggt ccacgttgga taatcgacaa cgcgtttatt ataaacacta tcatacacat
     1321 cattaccata gccgtagccc ttgatcgggt tttcctgaat cagtatccac gcggtgccct
     1381 gggttccgtt agtataacga tatgagctat ctgtctgctg taatttataa agtaaatgtt
     1441 ctgggtctgg tttgttagta tgttgagtga taaccaaagc gccgataatg gctaataaaa
     1501 tggcaccaac tcctattaac ttccattggc gattcagtat tgcccataga acacctacta
     1561 tgagcactgc caaccatccc cctcgcgata gggttcccag gataaagaaa aggtagatag
     1621 cgctaagcac caaaaaaacc aacttaattg aattttttct aaacaaccaa atattcaata
     1681 atgctggaaa taagaaaacc atggaatcgg acatatgtcg atgcg
//
LOCUS       DAJVBX010000332         1720 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.334, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000332 DAJVBX010000000
VERSION     DAJVBX010000332.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1720
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.334"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            444..>1720
                     /gene="hilA"
                     /locus_tag="OPV72_004413"
     CDS             444..>1720
                     /gene="hilA"
                     /locus_tag="OPV72_004413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator HilA"
                     /protein_id="HCR9916532.1"
                     /translation="MPHFNPVPVSNKKFVFDDFILNMDGSLLRSEKKVNIPPKEYAVL
                     VILLEAAGKIVSKNTLLDQVWGDAEVNEESLTRCIYALRRILSEDKEHRYIETLYGQG
                     YRFNRPVVVVSPPAPQPTTHTLAILPFQMQDQVQSESLHYSIVKGLSQYAPFGLSVLP
                     VTITKNCRSVKDILELMDQLRPDYYISGQMIPDGNDNIVQIEIVRVKGYHLLHQESIK
                     LIEHQPASLLQNKIANLLLRCIPGLRWDTKQISELNSIDSTMVYLRGKHELNQYTPYS
                     LQQALKLLTQCVNMSPNSIAPYCALAECYLSMAQMGIFDKQNAMIKAKEHAIKATELD
                     HNNPQALGLLGLINTIHSEYIVGSLLFKQANLLSPISADIKYYYGWNLFMAGQLEEAL
                     QTINECLKLDPTRAAAGITKLWITYYHTGIDDA"
BASE COUNT          535 a          379 c          347 g          459 t
ORIGIN      
        1 gagaaaaatg gttctgatgg tgtaattatc agaccattaa ccatgaagat ataataagca
       61 gcatttacac ccccaaaaaa tgcagtaaga tagctacaaa actaatctct attgcaatga
      121 gaccaagtta aatatgtaaa tatttagatg cccggcgctg actctcggca ccaggatata
      181 cgacagcgtc cattcgacaa tcacggttag ttataacaat atcattacca acatgtcagt
      241 tatttaaagc acaggcataa gctaaataat caaatgttaa aaacatataa acccgagccc
      301 gtacaatatg acattaagct cataataaaa gctcaacctg accgttagta ctagcagcag
      361 aattactgaa acagtagatt ctatcctaac gacttgtatt agctattata acttttcacc
      421 ctgtaagaga atacactatt atcatgccac attttaatcc tgttcctgta tcgaataaaa
      481 aattcgtctt tgatgatttc atactcaaca tggacggctc cctgctacgc tcagaaaaga
      541 aagtcaatat tccgccaaaa gaatatgccg ttctggtcat cctgctcgaa gccgccggca
      601 agattgtgag taaaaacacc ttattggacc aagtatgggg cgacgcggaa gttaacgaag
      661 aatctcttac ccgctgtatc tatgccttac gacgtattct gtcggaagat aaagagcatc
      721 gttacattga aacactgtac ggacagggtt atcggtttaa tcgtccggtc gtagtggtgt
      781 ctccgccagc gccgcaacct acgactcata cattggcgat acttcctttt cagatgcagg
      841 atcaggttca atccgagagt ctgcattact ctatcgtgaa gggattatcg cagtatgcgc
      901 cctttggcct gagcgtgctg ccggtgacca ttacgaagaa ctgccgcagt gttaaggata
      961 ttcttgagct catggatcaa ttacgccccg attattatat ctccgggcag atgatacccg
     1021 atggtaatga taatattgta cagatcgaga tagttcgggt taaaggttat cacctgctgc
     1081 accaggaaag cattaagttg atagaacacc aacccgcttc tctcttgcaa aacaaaattg
     1141 cgaatctttt gctcagatgt attcccggac ttcgctggga cacaaagcaa attagcgagc
     1201 taaattcgat tgacagtacc atggtctact tacgcggtaa gcatgagtta aatcaataca
     1261 ccccctatag cttacagcaa gcgcttaaat tgctgactca atgcgttaat atgtcgccaa
     1321 acagcattgc gccttactgt gcgctggcag aatgctacct cagcatggcg caaatgggga
     1381 tttttgataa acaaaacgca atgatcaaag ctaaagaaca tgcgattaag gcgacagagc
     1441 tggaccacaa taatccacaa gctttaggat tactggggct aattaatacg attcactcag
     1501 aatacatcgt cgggagtttg ctattcaaac aagctaactt actttcgccc atttctgcag
     1561 atattaaata ttattatggc tggaatcttt tcatggctgg tcagttggag gaggccttac
     1621 aaacgattaa cgagtgttta aaattggacc caacgcgcgc agccgcaggg atcactaagc
     1681 tgtggattac ctattatcat accggtattg atgatgctat
//
LOCUS       DAJVBX010000333         1695 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.335, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000333 DAJVBX010000000
VERSION     DAJVBX010000333.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1695
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.335"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            4..942
                     /gene="pgtE"
                     /locus_tag="OPV72_004414"
     CDS             4..942
                     /gene="pgtE"
                     /locus_tag="OPV72_004414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="omptin family outer membrane protease PgtE"
                     /protein_id="HCR9916533.1"
                     /translation="MKKHAIAVMMIAVFSESVYAESTLFIPDVSPESVTTSLSVGVLN
                     GKSRELVYDTDTGRKLSQLDWKIKNVATLQGDLSWEPYSFMTLDARGWTSLASGSGHM
                     VDHDWMSSEQPGWTDRSIHPDTSANYANEYDLNVKGWLLQGDNYKAGVTAGYQETRFS
                     WTARGGSYIYDNGRYIGNFPHGVRGIGYSQRFEMPYIGLAGDYRINDFECNVLFKYSD
                     WVNAHDNDEHYMRKLTFREKTENSRYYGASIDAGYYITSNAKIFAEFAYSKYEEGKGG
                     TQIIDKTSGNTAYFGGDAAGIANNNYTVTAGLQYRF"
     gene            1128..1274
                     /locus_tag="OPV72_004415"
     CDS             1128..1274
                     /locus_tag="OPV72_004415"
                     /inference="COORDINATES: protein motif:HMM:NF020812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916534.1"
                     /translation="MYSLWDCFNLWADIGNEKDRPGDYSLSEYPVHQLPTNHLVDGLV
                     AIGS"
     gene            1290..1433
                     /locus_tag="OPV72_004416"
     CDS             1290..1433
                     /locus_tag="OPV72_004416"
                     /inference="COORDINATES: protein motif:HMM:NF020812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916535.1"
                     /translation="MDGWGSYVSNILMQDCAGSGGLWYTYGKTFTYISVIDTKTLTLT
                     NCL"
BASE COUNT          481 a          319 c          416 g          479 t
ORIGIN      
        1 gaaatgaaaa aacatgctat tgcagtaatg atgatcgccg tattttctga gtcggtttat
       61 gcggagtcta ccttatttat tccggacgtc tctcctgaga gcgtcacgac atccctttct
      121 gtgggggtgt taaacggtaa atccagggag ctggtttatg ataccgacac cggacggaag
      181 ctgagtcaac tggactggaa aataaaaaat gtcgccacgt tgcaggggga tttatcatgg
      241 gaaccctatt cgttcatgac gctggacgcc cgcggctgga cgtctttggc gtcgggatcg
      301 ggtcatatgg ttgaccatga ctggatgagc agtgagcagc caggctggac cgatcgttca
      361 attcatccgg acaccagcgc caactatgct aatgaatacg atttgaacgt gaaaggttgg
      421 ttattgcagg gagataacta caaggcgggc gtaacagcgg gctatcagga aactcgtttt
      481 agctggacgg caagaggcgg gtcttatatt tatgataatg gtcgatatat tggtaacttt
      541 cctcatggcg tgcgcggtat aggttatagc cagcgtttcg aaatgcccta tatcgggctg
      601 gcgggtgatt atcgtattaa tgactttgag tgtaatgtac tgtttaaata cagcgactgg
      661 gtaaatgcgc atgataatga cgaacactac atgcgaaaac ttaccttccg tgaaaaaacg
      721 gaaaattcac gatattatgg cgcgtctatt gacgccggat attatattac cagtaatgca
      781 aaaatctttg ctgagttcgc ttacagtaaa tatgaagaag gtaagggcgg tacgcaaatc
      841 atagataaaa ccagcggtaa tacggcgtat tttggtggcg atgccgcagg tatagctaat
      901 aataactata cggttaccgc ggggttgcag taccgcttct agaccacatc gggatgtcat
      961 cggtcataac cggccgatga cgactttttg ctgaacgtgt ggcatgcccg gtgatattgt
     1021 gtttacctca tatagatctg gcgagtttgg cgttaagacg tggcaaggaa cagtagaggg
     1081 ggacctcatc cagatgttat aaacttcaat tcagaaagtt actttccata tactctttgt
     1141 gggactgctt caacctttgg gcagatatcg gaaatgaaaa agatagacca ggcgactatt
     1201 cgctatcaga atatccggta caccaactac caacaaatca tttagtcgat ggtctcgttg
     1261 ccattggttc atagagtgtt ggtcttggta tggatggctg gggaagttat gtatcgaaca
     1321 ttcttatgca agattgcgca gggtctggtg gtctatggta cacatatggg aagacattca
     1381 catatatttc tgtaatcgat actaaaactt taacactaac taattgtttg tagaaagtgg
     1441 ttgcattatt aatggtttga gactcattga cataaaacaa acaccatctg gtaatctgtc
     1501 agaccccgca tcctcaacag ttaactataa agattgtatg gtagctgaga tgtcattagt
     1561 cctaatatcg tgtcagataa atttataaaa gattactcat gttttgtgtc acatgcaaaa
     1621 ataattcggc ttcgttaagg tctttagggg aaatacctaa tggataatta gttagattaa
     1681 cgttaacaac acttt
//
LOCUS       DAJVBX010000334         1692 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.336, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000334 DAJVBX010000000
VERSION     DAJVBX010000334.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1692
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.336"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            156..1361
                     /gene="yedE"
                     /locus_tag="OPV72_004417"
     CDS             156..1361
                     /gene="yedE"
                     /locus_tag="OPV72_004417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016156840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium metabolism membrane protein YedE/FdhT"
                     /protein_id="HCR9916536.1"
                     /translation="MSWQHFKQTWLIKFWAPAPAVIAAGILSTYYFGITGTFWAVTGE
                     FTRWGGQILQLFGVHAEQWGYYKLIHLEGTPLTRIDGMMILGMFGGCFAAALWANNVK
                     LRMPRSRIRIVQAVVGGMIAGFGARLAMGCNLAAFFTGIPQFSLHAWFFALATAIGSW
                     FGARFTLLPIFRIPVKMQKVSAASPLTQKPDQARRRFRLGMLVFIGMIGWALLTAMHQ
                     PKLGLAMLFGVGFGLLIERAQICFTSAFRDLWISGRAHMAKAIIFGMAVSAIGIFSYV
                     QLGVAPKIMWAGPNAVIGGLLFGFGIVLAGGCETGWMYRAVEVQVHYWWVGLGNVIGS
                     TILAYYWDDFAPALATSWDKVNLLNTFGPLGGLLVTYLLLFTALMLIIGWEKRFFRRA
                     GLTPAKESV"
     gene            1358..1591
                     /gene="yedF"
                     /locus_tag="OPV72_004418"
     CDS             1358..1591
                     /gene="yedF"
                     /locus_tag="OPV72_004418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase-like selenium metabolism
                     protein YedF"
                     /protein_id="HCR9916537.1"
                     /translation="MKNIVPDYRLDMVGEPCPYPAVATLEAMPQLKKGEILEVVSDCP
                     QSINNIPLDARNHGYTVLDIQQDGPTIRYLIQK"
BASE COUNT          329 a          438 c          494 g          431 t
ORIGIN      
        1 tgtggcatta aagccctgac gccgccagcc tttccaggcg ctggccgcaa tttgatccag
       61 tcggtattac cgcttattag gtgtaggcaa attctgtgat cggtgtagta tgcgcacttc
      121 ttgtttcaca ccttctgagt tcagaggcta aacacatgtc atggcaacac ttcaagcaaa
      181 cctggttaat taaattctgg gcgccggccc ctgcggtgat cgcagccggt attctctcta
      241 cctactattt tggcatcacc ggcacgtttt gggccgtgac gggcgaattt acccgctggg
      301 gcgggcaaat tttgcagctt tttggcgttc atgccgaaca gtggggctac tacaagctga
      361 ttcatctgga aggtacgccg ctgacgcgta tcgacggcat gatgatcctc ggcatgttcg
      421 gcggctgttt cgccgcggcg ctgtgggcca acaacgtaaa actgcgtatg ccgcgcagcc
      481 gaatccgtat cgtacaggcg gtggtcggag gcatgatcgc tggcttcggc gcgcgtctgg
      541 cgatggggtg taacctggcc gcctttttta ccgggatccc gcagttctcc ctacacgcgt
      601 ggttctttgc gctggcgacc gctatcggtt cctggttcgg cgcccgcttt acgttgctgc
      661 cgatatttcg cataccggtg aaaatgcaaa aggtctccgc ggcttcgcca ctgacgcaga
      721 aaccggatca ggcaagacgg cgtttcaggc tcggtatgct ggtctttatc ggcatgattg
      781 gctgggcgtt attaacggca atgcatcagc cgaaactggg gctggcgatg ctgttcggcg
      841 tcgggtttgg gctgctgatc gagcgcgcgc aaatctgctt tacctcggcc tttcgcgatc
      901 tgtggatctc cggacgcgcc catatggcga aagcgattat ttttggcatg gcggtcagcg
      961 ccattggtat tttcagctac gtgcagttgg gcgttgcacc taaaattatg tgggctggcc
     1021 cgaatgcggt cattggcgga ctgctgttcg gttttggcat cgtgctggcg ggcggctgcg
     1081 aaaccggctg gatgtaccgc gccgtagaag tccaggtgca ttactggtgg gtgggcctcg
     1141 gcaatgtcat cggttcgacc atcctggctt actactggga tgatttcgcg cccgcgctgg
     1201 cgaccagttg ggataaagtt aacctgctga atacctttgg tccgctgggg ggtctgctgg
     1261 tcacctatct gttgttattt accgcgctga tgttaatcat cggctgggaa aaacgttttt
     1321 tccgccgtgc ggggctgacg cctgctaagg aatctgtatg aaaaatatcg tccctgatta
     1381 ccgtctggat atggttggcg aaccttgccc gtacccggcg gtcgccactc tggaagcgat
     1441 gccgcagcta aaaaaaggtg agatcctgga agtggtcagc gactgtccgc agtccattaa
     1501 taatattcca ctggatgcgc gcaatcacgg ttatacggtg ctggatattc agcaggatgg
     1561 cccgacaatt cgttatctga ttcaaaaata agcgcatact cccgctgtac gttacggcgg
     1621 gagacctttt acggcataac cggcaaaaat ctaaaacgca taaaagaaat cagacaaggt
     1681 cgtcttgtgc gc
//
LOCUS       DAJVBX010000335         1676 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.337, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000335 DAJVBX010000000
VERSION     DAJVBX010000335.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1676
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.337"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            84..527
                     /locus_tag="OPV72_004419"
     CDS             84..527
                     /locus_tag="OPV72_004419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCR9916538.1"
                     /translation="MKTYIINSNCIYNEGKYELRTVSNSQVIKMTAMRAKCLSFIIEN
                     AHLEIIERQKITTALWGSRSHYVNDANLTQILYLIRRDLKALGINDLFITIPRQGLKV
                     NSDIAIIATDSETKGRKKQIVRQTIAALTTVFSVTLGSLMYLHIH"
     gene            544..1077
                     /locus_tag="OPV72_004420"
     CDS             544..1077
                     /locus_tag="OPV72_004420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 108 protein"
                     /protein_id="HCR9916539.1"
                     /translation="MNPIIDGIIALEGGYVFNPKDKGGATHWGITEATARAHGYAGDM
                     RDLTHAEAYAILEEDYWIKPGFDVISTLSWPVSFELCDAAVNIGDYHPSAWLQRWLNV
                     FNHEGKRYPDVHVDGNIGPRTLAALEHYLAWRGQEGEAVLVKALNCSQGMYYLNVAEK
                     NHNNEQFIYGWIKNRVT"
     gene            complement(1138..1482)
                     /locus_tag="OPV72_004421"
     CDS             complement(1138..1482)
                     /locus_tag="OPV72_004421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HCR9916540.1"
                     /translation="MSIPNHVSTTEVVLLELEILLTIISIGAWGGFVSYLLRKDKTEY
                     NSSHESIKYCLTQIVISCFTSFLLSAIAIEKECSFNIVLLAAGLGGVFASPILKILGR
                     RIKKIIGGNNSD"
BASE COUNT          537 a          352 c          362 g          425 t
ORIGIN      
        1 gtgacattta ttggattaag acatttctca tacaatatag tcaccacaga caaccaggat
       61 gtacatttct aaaggaagac gttatgaaaa cttatatcat taatagcaat tgcatttaca
      121 atgaaggtaa atatgaactg aggacggtct caaattcaca ggttattaaa atgactgcga
      181 tgagagccaa atgtctcagt ttcatcatcg agaatgctca tctggagatt atcgagcgac
      241 aaaaaataac cactgcgtta tggggaagtc gaagccacta tgttaatgat gcaaatctaa
      301 cgcagattct ctatttaatc agacgtgacc ttaaagcgct tggtattaat gatcttttta
      361 ttaccattcc aagacaaggt ctcaaagtga atagtgatat cgccattatc gcgacggata
      421 gcgaaacaaa gggaagaaaa aaacagattg tacggcaaac catcgctgcc ctgacgaccg
      481 tattttcagt aacgttaggt tctctcatgt atctgcatat tcactaagcg aaggaaaggg
      541 aagatgaatc caattataga tggaattatt gcgcttgaag gcggttacgt atttaaccct
      601 aaagataaag gcggcgccac tcattggggc attaccgaag ccacggcgcg agcgcatggc
      661 tatgctggcg atatgcggga tctgacccac gctgaagcct acgcgattct cgaagaggat
      721 tactggataa aaccaggctt tgatgtcatc tcgacgctat cgtggccagt ctcattcgag
      781 ctgtgcgatg cggcagtcaa cataggcgat taccacccca gcgcgtggct gcaacgctgg
      841 ctgaacgtct ttaatcacga aggtaaacgc tacccggatg ttcatgtgga tggcaatatt
      901 ggcccgcgga cgcttgccgc tctcgaacat tatttggcct ggcgaggcca ggaaggggaa
      961 gccgttttgg tgaaagccct caattgcagt cagggcatgt actacttaaa cgttgctgag
     1021 aaaaaccaca ataacgaaca atttatttat ggctggatca agaacagagt gacctagacc
     1081 aggctgaaaa aagacgcgta aaaggctcac ggatgagcct gatattgcga atgacaatta
     1141 atctgaatta tttcctccga taattttttt aattcgccgc ccaagaattt ttaagatcgg
     1201 actcgcgaaa acaccgccta agcctgccgc caacaggaca atattgaaac tgcattcttt
     1261 ttcgatcgca atcgcgctta acaaaaagct ggtgaagcag gaaatcacga tctgcgttaa
     1321 gcaatattta atactttcat gagaactatt atattctgtc ttatctttgc gtaaaagata
     1381 gctaacaaag cctccccacg cgccaatcga aataatagtg agtaagatct ctagctccaa
     1441 tagcacaact tccgttgtcg acacatggtt gggaatagac attttaacac cccgaaatca
     1501 ttataaatga ataattaaca caaggagtgt aagcgccctg tcagaagggt aaaaatcaaa
     1561 gcacatcatt taaaaccata ttaaatcaaa gcgtaaaaat gaggtgtgtt agcgacggaa
     1621 ggaggaaagt gtttgcaaca tacttaccat ctcattaatc gtcgatatat ttctac
//
LOCUS       DAJVBX010000336         1633 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.338, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000336 DAJVBX010000000
VERSION     DAJVBX010000336.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1633
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.338"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            287..823
                     /locus_tag="OPV72_004422"
     CDS             287..823
                     /locus_tag="OPV72_004422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin family protein"
                     /protein_id="HCR9916541.1"
                     /translation="MNKMLLAGSAGIVLLSAAASPVWADDNASTFSLGYAQSHTNHAG
                     TLRGVRLANNYEMSPDWGLTTSFAWLNGSQRYSDESSNGRVTTRYYSLLAGPSWKINN
                     QLSLYSQVGPVLLHQRDHGINESDSKVGYGYSAGVAYTPVSNVAITLGYEGADFDATH
                     NSGSLNSNGFNLGVGYRF"
     gene            870..1502
                     /locus_tag="OPV72_004423"
     CDS             870..1502
                     /locus_tag="OPV72_004423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfdX family protein"
                     /protein_id="HCR9916542.1"
                     /translation="MKSHIMPGVALMVILFSGNLMAATNMTDNVTLNNDKISGQAWQA
                     MRDIGMSRFELFNGRTQKAEQLAAQAEKLLNDDSTDWNLYVKSDKKAPVEGDHYIRIN
                     SSITVAEDYLPAGQKNDAINKANQKMKEGDKKGTIEALKLAGVSVIENQELIPLQQTR
                     KDVTTALSLMNEGKYYQAGLLLKSAQDGIVVDSQSVQESPTHPVQHDAAH"
BASE COUNT          472 a          337 c          379 g          445 t
ORIGIN      
        1 gggactcact cccttgccgc ctttcagcaa ctcaaattat ttttggtata tatcagtgaa
       61 cttctatttt tgtcagtttt tatttttcag tttatttatt attaaatact gtttctggcc
      121 tggatatatt ttcgtgaata gcctcccgat agccggagat aaaggtattt gctggcgtaa
      181 cagtgctcat aatttaaaag atttatttat agtttgttat cacggaaaga ttttaactta
      241 atacatgcca gtaaggcatc aggtaaaaat aaccggagag aagaagatga acaaaatgct
      301 attagccgga agtgccggta ttgttctgct gtctgctgca gccagtccgg tatgggcaga
      361 cgataatgcc agtacatttt cacttggata cgcccagtcc catactaatc acgccgggac
      421 gttgcgtggg gttcggctgg caaacaacta tgaaatgtca ccggactggg ggctgacaac
      481 ctcatttgcc tggctaaatg gaagccagcg ctattccgat gaaagcagta atggtcgtgt
      541 aacaacccgt tattactccc tgcttgcagg cccctcatgg aaaataaata accagttaag
      601 tctgtatagt caagtgggcc ccgtattatt gcatcagcgt gatcacggga taaatgagtc
      661 tgatagtaag gtcggatatg gttattctgc tggcgtggct tataccccgg tcagtaatgt
      721 cgctataact ctgggttatg agggagcgga ttttgatgct acccataaca gcggaagcct
      781 taatagcaat ggttttaatc ttggcgtggg ttaccggttc tgaataggat aatccgataa
      841 aaaatgttac tttgtggaga tgatggatta tgaaaagcca tattatgcca ggcgttgcgc
      901 tgatggttat cctgttttca ggaaatctta tggccgcaac aaacatgact gataacgtta
      961 ctctgaataa tgacaagata tccggacagg cctggcaggc catgcgtgat atcggaatgt
     1021 cgcgattcga gttgtttaat ggtcgcaccc aaaaggcgga acaactggct gcgcaagcag
     1081 aaaaactcct gaacgatgac agcactgact ggaatctgta tgtcaaatca gataaaaaag
     1141 ccccagttga aggagaccac tatattcgga taaattcatc gattacggta gccgaagatt
     1201 atctccctgc gggccagaaa aatgatgcta ttaataaagc aaaccagaaa atgaaagaag
     1261 gagataaaaa agggactata gaggccctga aactagcagg cgtcagtgtt attgaaaatc
     1321 aggaactcat tcctcttcag caaacccgta aggatgtgac tacagcgctt tccttgatga
     1381 acgaaggaaa atactatcag gcaggtctgt tactgaaatc agctcaggat ggcatagttg
     1441 tagactctca gtcagttcag gaatcaccca cgcaccccgt gcagcacgac gccgcgcatt
     1501 aatatccccc agcctgctgt atatattaca gcaggcagca ttatgtctga cagccattac
     1561 cagtttgttc tttgctgtcg gcattgtttt taaaattcat ccgtgaagtt caggaatatc
     1621 agggtacctg cat
//
LOCUS       DAJVBX010000337         1628 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.339, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000337 DAJVBX010000000
VERSION     DAJVBX010000337.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1628)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1628)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1628
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.339"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            268..1587
                     /gene="brnQ"
                     /locus_tag="OPV72_004424"
     CDS             268..1587
                     /gene="brnQ"
                     /locus_tag="OPV72_004424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transporter carrier
                     protein BrnQ"
                     /protein_id="HCR9916543.1"
                     /translation="MTHQLKSRDIIALGFMTFALFVGAGNIIFPPMVGLQAGEHVWTA
                     AIGFLITAVGLPVLTVVALAKVGGGVDSLSTPIGKVAGLLLATVCYLAVGPLFATPRT
                     ATVSFEVGIAPLTGDSAMPLLIYSVVYFAIVILVSLYPGKLLDTVGNFLAPLKIIALV
                     ILSVAAIVWPAGPISNALDAYQNAAFSNGFVNGYLTMDTLGAMVFGIVIVNAARSRGV
                     TEARLLTRYTVWAGLMAGVGLTLLYLALFRLGSDSATLVDQSANGAAILHAYVQHTFG
                     GAGSFLLAALIFIACLVTAVGLTCACAEFFAQYIPLSYRTLVFILGGFSMVVSNLGLS
                     HLIQISIPVLTAIYPPCIALVVLSFTRSWWHNSTRIIAPAMFISLLFGILDGIKASAF
                     GDMLPAWSQRLPLAEQGLAWLMPTVVMVILAIIWDRAAGRQVTSSAH"
BASE COUNT          285 a          421 c          459 g          463 t
ORIGIN      
        1 gttttattct ggttgtaaat ttcatatcgc gatattcatc tggtttttag atcccacctt
       61 gctttaaaac gttataagcg tttaaattgc gcttcaggtg ctgtcattac gactgcattt
      121 gcgcggtaaa tcgaaaaaca attcttcgcc gcatcggtcc gggagttttt cccgctgaaa
      181 ttgataaaaa acgccgcttt ataatcctcc gggaaaggca aaaattttaa tgtttacaac
      241 atcaccatcc acaggcagta agactttatg acccatcagt taaaatcgcg cgatatcatc
      301 gccctgggct ttatgacatt tgcgctgttc gttggcgcag gcaatattat ctttcctcct
      361 atggtcggtt tgcaggcggg tgaacacgtc tggacagccg ctattggctt tctgattacc
      421 gccgtagggc taccggttct tactgttgtg gcgctggcga aagtcggcgg cggcgtagac
      481 agcctcagta cgccgattgg taaagtggcg ggactcctgc tggcgaccgt ttgctatctg
      541 gccgtcgggc cgttatttgc gacgccgcgt accgcgacgg tgtcgtttga ggtcggtatc
      601 gctccgttga ccggcgattc tgcaatgccg ttgctgattt acagcgtggt ctatttcgct
      661 atcgttattc tggtttccct ctatccgggt aagctgctgg atacggtagg gaatttcctg
      721 gcgccgttga aaattattgc gctggtcatc ctgtccgtcg cggctatcgt ttggcctgcc
      781 ggtccaatca gcaacgccct ggacgcttat cagaatgcgg ccttttctaa cggatttgtg
      841 aacggctatc tgacgatgga tacgctgggc gcgatggtgt ttggtatcgt tattgtgaac
      901 gcggcgcgtt ctcgcggcgt gaccgaagcg cgcctgttga cgcgttacac ggtctgggcc
      961 ggcctgatgg cgggcgtggg gctgacgctg ctttaccttg ccttgtttcg cttaggttct
     1021 gacagcgcga cgctggtcga tcagtcagcg aacggcgcgg cgattcttca tgcctacgtt
     1081 cagcatacct ttggcggcgc gggaagcttc ctgctggcgg cgctgatctt tatcgcgtgt
     1141 ctggtgacgg cggtggggct gacctgcgcc tgcgctgagt ttttcgcgca gtatattccg
     1201 ctgtcttacc gcacgctggt ctttattctc ggcggcttct ctatggtggt gtcaaatctc
     1261 ggactgagcc atctgattca aatctccatt ccggtgctga cggctatcta tccgccgtgt
     1321 atcgcactgg ttgtattaag ttttacccgc tcatggtggc ataattccac ccgtatcatc
     1381 gcgccggcca tgtttatcag cctgcttttt ggtatccttg acggcatcaa agcatctgcc
     1441 tttggcgata tgctgccagc ctggagtcag cgtttgccgc tggcggaaca gggactggcg
     1501 tggttgatgc caacggtggt gatggtgatc ctggcgatta tctgggatcg cgcggcgggt
     1561 cggcaggtga cctccagcgc tcactaaaat cgctgacata tgtgtacacc acggggctta
     1621 acgccccg
//
LOCUS       DAJVBX010000338         1621 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.340, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000338 DAJVBX010000000
VERSION     DAJVBX010000338.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1621
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.340"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(96..776)
                     /gene="pipA"
                     /locus_tag="OPV72_004425"
     CDS             complement(96..776)
                     /gene="pipA"
                     /locus_tag="OPV72_004425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system effector protease
                     PipA"
                     /protein_id="HCR9916544.1"
                     /translation="MLPVTYRLIPQSGVSTYGLNTADTPVFPDIPEHAPNPSRLRLAH
                     DSLAINSEFRLEPECVVEYLISGAGGIDPDTEIDDDTYDECYDELSSVLQNAYTQSET
                     FRRLMNYAYEKELHDVEQRWLPGAGEAFETTVAQEHFKLSEGRKVICLNLDDSDDSYT
                     EHYESNEGRQLFDTKRSFTHEVVHALTHLQDKEENHPRGPVVEYTNIILKEMGHPSPP
                     RMVYIFNK"
     gene            complement(999..>1621)
                     /gene="pipB"
                     /locus_tag="OPV72_004426"
     CDS             complement(999..>1621)
                     /gene="pipB"
                     /locus_tag="OPV72_004426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="SPI-2 type III secretion system effector PipB"
                     /protein_id="HCR9916545.1"
                     /translation="VNGCTICLSCGAASENTDPMVTIEVNKNGKTVTDKVDSERFWNV
                     CRMLKLMSKHNIQQPDSLITEDGFLNLRGVNLAHKDFQGEDLSDIDASNADFRETNLS
                     NVNLVGANLCCANLHAVNLMGSNMTKANLTHADLTCANMSGVNLTAAILFGSDLTDTK
                     LNGAKLDKIALTLAKALTGADLTGSQHTPTPLPDYNDKTLFPHPIF"
BASE COUNT          431 a          308 c          345 g          537 t
ORIGIN      
        1 tgggcgctta gaatatagtt agaaaatact gctagaacat ttcccgaaaa aacggactac
       61 gtgggttttt agtttctttt cgtttcttga tgtgtctatt tattgaagat gtagaccatt
      121 ctgggaggtg aaggatgccc catctctttc agaataatgt tggtatattc gacaacaggg
      181 cctcttggat gattttcttc tttatcctga agatgggtca gtgcatgtac aacttcatga
      241 gtaaatgaac gttttgtgtc aaaaagttgt cttccttcgt tactttcata atgttcggta
      301 tatgaatcat cagaatcgtc cagattgaga caaataactt tcctgccttc tgaaagtttg
      361 aagtgttcct gagccacggt agtttcaaag gcttcgcctg cccccggtag ccagcgctgc
      421 tccacatcat gtagttcttt ttcatatgcg taattcatca gtctgcggaa tgtttcgctt
      481 tgggtatacg cattttgaag tacggaggat agttcatcgt agcattcgtc ataagtgtcg
      541 tcatcaattt ctgtatcagg gtctattcca cccgcgcctg agataaggta ctccaccaca
      601 cactctggct ccagacggaa ttcactgttt atggcaaggc tgtcatgagc aaggcgtagc
      661 cgtgaggggt ttggtgcatg ttcgggaata tcggggaaaa caggtgtatc tgcggtattt
      721 aatccatatg tggatactcc gctttgaggt attaatctgt aggtgaccgg aagcataatt
      781 tcttattccc tgactgcaat tatgaattat ttaaattaaa caataatagt gtttttagtt
      841 aatgtgccac atacagataa cgctatgatt caggcaaaac caacaagtaa tacgctgaaa
      901 atgttattta taatgaagct taggggcggg gtttgtttaa taaaacaagg agggcttctg
      961 tttgaatact tcttgtttat aaaatccctt tatctcgact aaaatattgg atgggggaaa
     1021 agcgttttat cattgtaatc cgggagtgga gtaggggtat gttgactacc tgtcagatcg
     1081 gctcctgtta atgctttcgc taaagttaga gctatcttat ctaattttgc accatttagt
     1141 ttggtgtcag ttaagtctga gccgaataga attgcagcgg ttaagtttac accggacatg
     1201 ttagcgcaag tcaggtctgc gtgagtcagg tttgctttag tcatgtttga acccattaga
     1261 tttacagcgt gtagatttgc acaacacaaa tttgcaccga ctaaatttac attagataga
     1321 tttgtttcac ggaaatctgc attagaagca tctatgtctg acaaatcttc tccctggaaa
     1381 tctttatgag ctaggtttac tccgcgcagg ttcagaaaac catcctcggt tataagtgaa
     1441 tcaggctgtt gtatattatg tttactcatc agttttaaca ttcgacatac attccaaaat
     1501 ctctcactat caactttatc cgttacagtt tttccatttt tgttcacttc aatagtgacc
     1561 atgggatccg tattttcgga tgctgctcca catgacagac atatagtaca cccgttgaca
     1621 t
//
LOCUS       DAJVBX010000339         1618 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.341, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000339 DAJVBX010000000
VERSION     DAJVBX010000339.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1618)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1618)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1618
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.341"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            161..>1618
                     /locus_tag="OPV72_004427"
     CDS             161..>1618
                     /locus_tag="OPV72_004427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000964108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="HCR9916546.1"
                     /translation="MAIFHLDFKIVKRSEGRSSVAKAAYHARTRITDERTGDTYDYSR
                     RTDLYGHFILAPANAPEHIVKDSTALWNEVEKVERQNNGQTSRYFDVAIPTELNNDDK
                     KKLVLEYCQKNFVDKGMIADIAFHDLDSDNPHAHVMLTLKAIGPEGFGKKERSWNDRK
                     MSVLWRESWASMANSYLEAAGSSERIDHRSLQAQHEEALEKAAAALDNEEQALWLAKA
                     AETNRPAMKRIHSAKWRSKAAQEQRAAEQAVRDAAKQEAVEVYKTFSELDLEIVVDVR
                     SFTITHLAEPEEIVLPETRSSSSTNEEQRPLLVAPAPDTRLRGVKSYRDKTKVSKVVA
                     CIPPSISISDSGTNTILKTSTSQNPNRASRSAPDHERKDKTTPRQDNIFKRFTTLVID
                     FFKEKFVWPRSSRVKHDPVSTEHDKRIAENYVFDEVLGHHVSRAEYEKQAKFNSDTYK
                     PTPDEIRRFPSRPKHERVNADNNMDFIPTVSTINDK"
BASE COUNT          520 a          340 c          335 g          423 t
ORIGIN      
        1 accgacggtt gcctgccgca ggctaacacc gtttccttcg gaaacaaggt caacgtcaac
       61 accagagttt ttcttgcgaa aaactaaaac cagcatagtc gcattggaga gttatatttt
      121 agtttgatat ttaaacttat attgaggttg tttttattgt atggctattt ttcatcttga
      181 ttttaaaatt gtgaaacgtt cagaaggcag gtcttccgtt gcgaaggctg cctatcatgc
      241 tcgtacaagg ataacagatg aaagaacagg tgatacctat gattatagtc gccgtactga
      301 tttgtacggg catttcatat tagctccagc taacgcacca gaacacatcg taaaagactc
      361 tacagcattg tggaatgaag tggaaaaagt tgagcgccag aacaatggtc aaacatcccg
      421 ttatttcgat gttgctattc ccaccgagtt aaacaatgac gacaagaaaa aacttgtcct
      481 tgagtattgt cagaaaaatt tcgttgataa aggcatgatt gccgacatcg cttttcatga
      541 tcttgatagc gacaacccac atgctcacgt tatgttgacg ttaaaagcca taggcccgga
      601 aggttttggt aaaaaagaaa gaagctggaa cgacagaaaa atgtctgtgt tgtggcgtga
      661 gtcatgggca tctatggcta acagctatct cgaagccgca ggttcatcag aacgtattga
      721 ccatcgttcc cttcaggccc agcatgaaga ggcattagaa aaagcggcgg ctgctctgga
      781 caatgaagaa caagcgctat ggcttgctaa agccgctgaa acaaaccgcc ctgcaatgaa
      841 acgtatccat agtgccaaat ggcgcagtaa agctgctcaa gagcaaagag ccgcagaaca
      901 ggctgttcgt gatgctgcca agcaagaagc cgttgaagtc tacaaaacat tcagcgaact
      961 tgatcttgaa atcgtcgttg atgtcagaag ctttacgatt acacatcttg ctgaaccaga
     1021 agaaattgtt ttaccagaaa cgcgatccag ctcttctaca aatgaagaac aaagaccttt
     1081 actggtagca ccagctcctg atactcgttt gcgtggagtc aaatcttacc gtgataaaac
     1141 aaaagtcagt aaggttgttg cttgtattcc gccatcaatc agtatttctg attctggtac
     1201 aaatactatt ctgaaaacat ccacctctca aaacccaaac agggcatcca gaagcgcccc
     1261 tgaccatgaa agaaaggata agactactcc acgtcaggat aatattttca aacgtttcac
     1321 aactcttgtc atagatttct tcaaagaaaa atttgtatgg cctagatcaa gcagagttaa
     1381 gcatgatcct gtcagtacag aacatgataa acgtattgct gaaaactatg tctttgatga
     1441 agtattaggt catcatgttt ctcgtgctga atatgagaaa caagctaagt ttaacagtga
     1501 tacttacaaa ccaacacctg atgagattcg acgtttccca agccgtccta agcacgaacg
     1561 agtcaatgca gataataaca tggattttat accgactgtt tcaacaataa atgataaa
//
LOCUS       DAJVBX010000340         1604 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.342, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000340 DAJVBX010000000
VERSION     DAJVBX010000340.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1604
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.342"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(410..1114)
                     /locus_tag="OPV72_004428"
                     /pseudo
     CDS             complement(410..1114)
                     /locus_tag="OPV72_004428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611456.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS481 family transposase"
     gene            1167..1472
                     /locus_tag="OPV72_004429"
     CDS             1167..1472
                     /locus_tag="OPV72_004429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001555868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system SymE family toxin"
                     /protein_id="HCR9916547.1"
                     /translation="MARLCGILTYSRVERLSVRLYGEWMPQAGFINGMPVKVRVMRDC
                     IVITPQHTRGLFVCIEGMGVTFINQKKVKAWLKTFPGALNDTGDIPVIKRSRLEGGI"
BASE COUNT          418 a          376 c          368 g          442 t
ORIGIN      
        1 agagaggata attatcaggc atcgttgcaa cattgtttat atttaaacat acatctccta
       61 actcgacggt aagattatta gttaactttt cctcgcaggg aagatcttta atggaaaatc
      121 ttgttttccg aaacggaaaa gcaattataa cgctccaacg agagtctcaa cactaagagc
      181 tgactgacac aggccagact gattatacag gcatgaaaaa gctctcccct tcctttcagt
      241 tcttgctgga ttatgcaaac gtcgcaccac ctccccgtga acatggcaca ttaatttgaa
      301 gcaactctca tccggtatcg cttttcagtg cagcgaaatt catcgcaggt gcccctgtaa
      361 atagacccgt tttagttcca tgcattttta agattccggc cagataacgt tattggcggt
      421 attcctccgg tatcatattg ttccgcgatt catgtggacg ttcgcagtta tattctgata
      481 accctttatc cgtaatttcc cgcacctcat tcagcgttct gaacagataa gaattgagta
      541 tttctgtacg gtatgtccgg ttaaaacgct cgatgaaaac gtttttcttc ggcttacccg
      601 gctggataaa cgccagcttt actacatgtt tctttgccca ttcagccagt gccagcgaga
      661 taaattccgg tcccttatcc atacgcagca tggccggata accgaggttg ctgtaatcct
      721 gtcgagtaca cggaccactc gcagagctgg cagattcaga tcgatttcaa tcgacaacgc
      781 ttcacgatta cagtcatcaa caacattgaa cgtgcgaaaa cgacgcccat aaaccagctc
      841 tggttcagcg cttccggcgt gaccagtggc gagggattgc gtaccggcag ccgttgttta
      901 cccttacggc gaaaattcag cttgagcaga cagtaaatac ggtggagcct tttgtgattc
      961 cacgcgtatc cctgccgccg tatccagacc tccagttatc cctggtggct tcagaaatac
     1021 cggcctcccg gtagacatct ttaacagtcc gtccggattc gactgatcta atcacaacga
     1081 tgatctggtg cgcagtaata cgggctttac gcatagcgat ctcctgcgtt ggcagattga
     1141 ttatgtcgga tgatctctaa atgtgaatgg ctcgattatg cgggatactt acatactcac
     1201 gcgttgagag actttcagtt cgtttgtacg gtgaatggat gccgcaggcg gggtttatta
     1261 acgggatgcc cgtcaaggtg cgggtaatga gggattgcat cgtgatcacg ccgcagcata
     1321 cccgcggact ctttgtctgt attgaaggga tgggcgtgac ttttattaat caaaagaagg
     1381 tgaaagcgtg gctaaaaacc tttccggggg cgctgaacga taccggggat attccggtga
     1441 ttaagcggag caggctcgaa ggcgggattt gacagggggt taaataataa aaaagccggg
     1501 aagagttaat ttctttcccg gctttattaa cacctaatgt attactggta tctattatac
     1561 aattctattt cagccagaac atattcactg aaaacatatt tagt
//
LOCUS       DAJVBX010000341         1579 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.343, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000341 DAJVBX010000000
VERSION     DAJVBX010000341.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1579)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1579)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1579
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.343"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            119..1048
                     /gene="hilD"
                     /locus_tag="OPV72_004430"
     CDS             119..1048
                     /gene="hilD"
                     /locus_tag="OPV72_004430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator HilD"
                     /protein_id="HCR9916548.1"
                     /translation="MENVTFVSNSHQRPAADNLQKLKSLLTNTQQQIKSQTQQVTIKN
                     LYVSSFTLVCFRSGKLTISNNHDTIYCDEPGMLVLKKEQVVNVTLEEVNGHMDFDILE
                     IPTQRLGALYALIPNEQQTKMAVPTEKAQKIFYTPDFPARREVFEHLKTAFSCTKDTS
                     KGCSNCNNKSCIENEELIPYFLLFLLTAFLRLPESYEIILSSAQITLKKRVYNIISSS
                     PSRQWKLTDVADHIFMSTSTLKRKLAEEGTSFSDIYLSARMNQAAKLLRIGNHNVNAV
                     ALKCGYDSTSYFIQCFKKYFKTTPSTFIKMANH"
BASE COUNT          507 a          327 c          294 g          451 t
ORIGIN      
        1 cttttggtgt aacaatcaga ccattgccaa cacacgctaa taaagagcat ttacaactca
       61 gattttttca gtaggatacc agtaaggaac attaaaataa catcaacaaa gggataatat
      121 ggaaaatgta acctttgtaa gtaatagtca tcagcgtcct gccgcagata acttacagaa
      181 attaaaatca cttttgacaa atacccagca gcaaattaaa agtcagactc agcaggttac
      241 catcaaaaat ctttatgtaa gcagtttcac tttagtttgc tttcggagcg gtaaactgac
      301 gattagcaat aatcacgata cgatttactg tgacgaacct gggatgttgg tgctcaaaaa
      361 agagcaggta gttaacgtga cgcttgaaga ggtcaatggc cacatggatt tcgatatact
      421 cgagataccg acgcaacgac ttggcgctct ctatgcactt atcccaaacg agcagcaaac
      481 caaaatggcg gtacccacag agaaagcgca gaaaatcttc tatacacctg actttcctgc
      541 cagaagagag gtatttgaac atctgaaaac ggcgttctcc tgtacgaagg atacaagcaa
      601 aggttgcagt aattgtaaca acaaaagttg tattgaaaat gaagagttaa ttccttattt
      661 tctgctgttc ctgcttactg cttttctccg actccctgag agttatgaga tcatccttag
      721 ctcggctcag ataacgttaa agaagcgcgt ttacaacatt atatcttcgt cacccagtag
      781 acagtggaag cttacggatg ttgccgatca tatatttatg agtacgtcaa cgctcaaacg
      841 gaaacttgca gaagaaggta ccagctttag cgatatctac ttatcggcaa gaatgaatca
      901 ggcagcaaaa cttttacgca taggcaacca taatgttaat gctgtagcat taaaatgtgg
      961 ttatgacagc acgtcctact tcattcaatg tttcaaaaaa tattttaaaa ctacgccatc
     1021 gacattcata aaaatggcga accattaaca tttttgtatc agtcactcaa gtaaagattt
     1081 ttattaaaat tttaataatt taaaattcag accgtgcatt aacacgctat atcaggatgg
     1141 gaggctattc aacatcattg ttctgtccgg aagacagctt atactgatat ctctggtaat
     1201 ttaaagtaag gctgattata taacacgatt tttgtgaact tgtcatcgct atgatgactg
     1261 gtaaaccgat attgccttat tcacagcgta agaatccgtc cagatgacac tatctccttc
     1321 cggctttaac cctatggatt aaggccggca ttttattcat atttatacat catccgttcc
     1381 ctctgagaac tatttgcctg aacggtctac accgaaacag tcacgcttgt tagctttctg
     1441 ccaggcatac atcttctctt catcctgata tcgatataat gcctgggggc cagcttgagg
     1501 atgatactgc tcataaaccc ctgccttttt gacgctatag ctgaaggagt aaagaaaaga
     1561 cgatatcatt attttgcaa
//
LOCUS       DAJVBX010000342         1547 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.344, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000342 DAJVBX010000000
VERSION     DAJVBX010000342.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1547)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1547)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1547
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.344"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..347
                     /gene="stpA"
                     /locus_tag="OPV72_004431"
     CDS             <1..347
                     /gene="stpA"
                     /locus_tag="OPV72_004431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA-binding protein StpA"
                     /protein_id="HCR9916549.1"
                     /translation="EFSIDVLEEMLEKFRVVTKERREEEELQQRQLAEKQEKINAFLE
                     LMKADGINPEELFAMDSAMPRSAKKRQPRPAKYRFTDFNGEEKTWTGQGRTPKPIAQA
                     LAAGKSLDDFLI"
     gene            complement(437..617)
                     /locus_tag="OPV72_004432"
                     /pseudo
     CDS             complement(437..617)
                     /locus_tag="OPV72_004432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000494935.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(696..1223)
                     /locus_tag="OPV72_004433"
     CDS             complement(696..1223)
                     /locus_tag="OPV72_004433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese family protein"
                     /protein_id="HCR9916550.1"
                     /translation="MSIGIVSPREAQALIAQGAKLIDVRDADEYLREHIPHAQLAPLS
                     RLEQGDLPANLRAEQIIFHCQSGKRTSSNAAKLQAIAAPAQVSLLEGGIDGWKAAGLP
                     VTEDKSQPLPLMRQVQIAAGGLTLLGVILGYTVHGGFFLISGFVGAGLMLAGITGFCG
                     MARLLEKMPWNTRTH"
     gene            complement(1233..1532)
                     /locus_tag="OPV72_004434"
     CDS             complement(1233..1532)
                     /locus_tag="OPV72_004434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HCR9916551.1"
                     /translation="MTELEKLQASAEQAAALLKAMSHPKRLLILCMLCGSPKTSAGEL
                     ARITGLSPSATSQHLARMREEGLIDSQRDAQRIHYFIKNEAVNTLIATLKNLYCP"
BASE COUNT          366 a          412 c          386 g          383 t
ORIGIN      
        1 gcgaattctc cattgatgtt cttgaagaaa tgctcgaaaa attcagggtt gtcactaaag
       61 aaagacgcga agaagaagaa ttgcagcaac gccagcttgc cgagaagcag gagaaaatta
      121 atgcctttct ggagctgatg aaagcagacg gtattaaccc ggaagagtta tttgccatgg
      181 attcagcaat gccgcgttct gctaaaaagc gccaaccgcg tccggcaaaa tatcgtttta
      241 ctgatttcaa tggcgaagaa aaaacctgga ccggacaagg tcgtacgcct aaaccgattg
      301 cccaggcgct ggcggcgggg aaatctctgg atgatttctt aatctaatca cggataacct
      361 ttaacagatg gcgctgcgtt tcctgtctct attaaccggg attcagggaa cgttgcgcca
      421 tgctcatttt gataaatcag cacacgccaa aatcgccctt ttcgcaatag ggggtgacat
      481 ctgccgcttt gaggatcaat ttttcgcccg gctcattacc gacctgtacc gcgacaatat
      541 gatcctcgtt gacttcaatc actttcagtt tcggcccccc ccattcgggg ctgtacgata
      601 tcgcctggtg tgaacatcac gtcctcccgt tgaacaatgg tataaacccg ccttcagtct
      661 actacacact taccgacgcg cggtgaaagt accgcttaat gagtacgggt attccagggc
      721 attttttcca gtagtcgcgc cattccgcag aagccggtta tgcctgccag cattaacccg
      781 gccccgacaa aaccgctaat gaggaaaaag ccgccgtgga ccgtatagcc cagaatcacc
      841 ccaagcaacg tcaacccgcc ggcggcgatt tgcacctgac gcatcagcgg caacggttgc
      901 gatttgtctt ctgtgacggg caatcctgcc gctttccatc cgtcgatacc gccttccagt
      961 aaactgactt gagcaggggc ggcaatggcc tgtagttttg ctgcattgct gctggttcgt
     1021 ttacctgact gacagtgaaa aataatctgt tccgctcgca ggttggcggg caaatcgccc
     1081 tgttcaagcc gggaaagcgg cgccagttgc gcatgtggaa tatgctcgcg cagatattca
     1141 tcggcgtcgc gcacatcaat cagtttcgcg ccttgcgcta tcagcgcttg cgcctcacgg
     1201 ggggaaacta tcccaatgga catcgtgcct ccttatggac aatagagatt ctttaacgtg
     1261 gcgataagcg tattaaccgc ctcattttta atgaaatagt gaatgcgctg ggcatcgcgt
     1321 tgactatcaa tcagcccttc ttcccgcatc cgcgccagat gctgcgacgt cgcggagggg
     1381 cttagcccgg taatgcgcgc cagttcgcct gcgctggttt ttggtgaacc gcaaagcata
     1441 cataaaatca gtaatctttt tgggtggctc atcgctttga gcagggccgc tgcctgttct
     1501 gcgctggcct gaagtttttc aagctctgtc atagttattt aagtgtt
//
LOCUS       DAJVBX010000343         1537 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.345, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000343 DAJVBX010000000
VERSION     DAJVBX010000343.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1537
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.345"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(361..1083)
                     /gene="fimY"
                     /locus_tag="OPV72_004435"
     CDS             complement(361..1083)
                     /gene="fimY"
                     /locus_tag="OPV72_004435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria biosynthesis regulator FimY"
                     /protein_id="HCR9916552.1"
                     /translation="MRSVPCRERHRRLRNAKDCACRYHSPTPQIFDRLELLNQQLNYA
                     LPVGIISQAIITTDNYLGYSLSHYLFSGKRTAAFRSLDDISLWIEKGSLRQLIVDMET
                     LPVSCIEALNQLHALSWQQSDIQIYLLVSDKTPAIAQFIRMAGRFFVLSRRQNLASVR
                     EALLSAAEPRLSESFSRTDWLMIETLAQGASLKEIARQQSVPYHRVVYRLKQLITLLN
                     LPHRQSFLRLIQQLNVTFHDIF"
     gene            complement(1102..1413)
                     /locus_tag="OPV72_004436"
     CDS             complement(1102..1413)
                     /locus_tag="OPV72_004436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HCR9916553.1"
                     /translation="MVAQGTLLKERINPPHLASSPTRHSYLNSGLLKSEPIVHLSTAQ
                     LIGYEVLTQLPSEHDSEVFFQQLMLMEGIETSEQRGIAFYAGATMGQGYLWPAILPDI
                     Y"
BASE COUNT          448 a          280 c          359 g          450 t
ORIGIN      
        1 gaaaagtctt gcgaaatgcg aattatggat agcgggtagg atgttctgtg acgttataga
       61 aaatttgttc gtggtggagc tattttcttt agagttgaca ttaagtagtt taaactgttg
      121 tttttaagta taaaaataat atgaaagact aattgtttag tatttgttat gtaataacag
      181 aaagatgttg acgctggaga ccgcaaaaaa caaggaggaa caggggacga tgtaagaaaa
      241 aattttttgt cgcttaccag gacgagttgt aaatattaat tttatgtgaa atatttacat
      301 ttaatggcag tgaaaataag taatttctta aaaaatctta ttcaccaaaa cgttacttcg
      361 ttaaaaaatg tcgtggaaag taacgtttag ctgctggatc agccgaagaa agctttgcct
      421 gtggggaagg ttaaggaggg tgataagttg tttaagccgg taaaccacac gatgataagg
      481 tacgctttgc tgacgtgcta tttcttttaa agaggcacct tgcgctaaag tttcaatcat
      541 caaccagtca gtacggctaa agctttccga taagcgaggt tcggcggctg ataacaaggc
      601 ttcgcgtaca gaggccagat tttgtcgtcg cgacaggaca aaaaaacgcc cagccatacg
      661 gataaactga gctatagcgg gggttttatc tgataccagc aggtaaatct ggatatcgct
      721 ttgttgccaa ctgagcgcgt gtagctggtt aagcgcctca atacaggaga caggtagcgt
      781 ctccatatct acaatcagtt gtctgagcga ccccttttca atccacaaag aaatgtcatc
      841 taatgagcgg aatgctgcgg tacgttttcc ggaaaataag tagtgactca atgaatagcc
      901 gaggtagtta tcagttgtaa ttattgcctg agaaatgata ccaaccggca aggcataatt
      961 tagctgttgg ttcagtaact caaggcgatc aaatatctgc ggcgttggag agtgataacg
     1021 gcaggcgcag tctttggcat ttcttaaacg gcggtgtctt tccctgcatg gtacgctgcg
     1081 catcctgctt tttccattgc tctaatatat atctggtaat atggctggcc ataaataacc
     1141 ttgtcccatc gttgcaccag cgtaaaaagc aatgcctcgt tgctctgatg tttcaatgcc
     1201 ttccatcagc attaactgct gaaaaaaaac ttcgctatca tgttctgacg gaagttgcgt
     1261 caggacctca tagccgatta attgcgcagt tgagagatga acgattggct cagattttaa
     1321 caatccgctg ttgagatatg aatggcgtgt tggcgaagac gccaggtgtg ggggatttat
     1381 cctttccttt aataaagtac cctgtgccac caaacactcc ttcaggcatt tatgatgcag
     1441 ccatatattt ttgacccctg aatctatcag gatattatgg gtatcattgt ggcagcgtta
     1501 aaaaaatgcc tgtaggtatc gttacttaat tattggt
//
LOCUS       DAJVBX010000344         1520 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.346, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000344 DAJVBX010000000
VERSION     DAJVBX010000344.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1520
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.346"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(127..279)
                     /locus_tag="OPV72_004437"
     CDS             complement(127..279)
                     /locus_tag="OPV72_004437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916554.1"
                     /translation="MPICTRLTAQIVKVAVNQPVAIRSSMWAKNNQNIHFMNLHVKKL
                     EKLLLF"
     gene            complement(359..1297)
                     /gene="lrhA"
                     /locus_tag="OPV72_004438"
     CDS             complement(359..1297)
                     /gene="lrhA"
                     /locus_tag="OPV72_004438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LrhA"
                     /protein_id="HCR9916555.1"
                     /translation="MINANRPIINLDLDLLRTFVAVADLNTFAAAAAAVCRTQSAVSQ
                     QMQRLEQLVGKELFARHGRNKLLSEHGIQLLGYARKILRFNDEACSSLMFSNLQGVLT
                     IGASDESADTILPFLLSRISSVYPKLALDVRVKRNAYMVDMVKSQEVDLVVTTNQPHS
                     LDCLNLRTSPTHWYCAAEYVLQRGEPVPLVLLDDPSPFRDMVLETLNAAGIPWRLAYV
                     ASTLLAVRAAVKAGLGVTARPVEMMSPDLRVLGAADGLPPLLDTEYMLCRDPNSQNEL
                     AMVIFHAMESYQNPWHYNQFSAEGGDDPLMVEGGFE"
BASE COUNT          405 a          388 c          334 g          393 t
ORIGIN      
        1 ttgaatcgtg tccgttgtga agcaaaagaa ataacacaca cctattttga caggaatttg
       61 tgaagatgcc tccccctaaa tgggagtatt ttcttgatct gtgacacgct tttgttaatt
      121 caccccctaa aacagcaaca atttctctag ttttttaaca tgcaaattca taaaatggat
      181 gttctggtta ttttttgccc acattgaact gcgaatcgct actggctgat ttaccgcaac
      241 ttttacaatt tgtgcggtta agcgcgtaca gatgggcaca aaaaaagagc cactgagcgt
      301 tttttcatcg ccagcggctc ttttttacat ttacgactta gcgccttttg cctgcgagct
      361 actcaaaacc cccttccacc atcagcggat catctccgcc ctctgcagaa aactggttgt
      421 aatgccatgg gttttgatag ctttccatcg catggaaaat caccatcgcc agctcgttct
      481 ggctattggg atcgcggcac aacatatatt ccgtatccag caaaggcggt aatccatctg
      541 cggcgcccag cacgcgaagg tcgggactca tcatttcgac aggtcgagcc gttacgccaa
      601 gaccggcttt aacggccgcg cgtaccgcca gtaatgtaga ggccacatag gccagccgcc
      661 agggaatacc cgctgcattt agcgtctcca gcaccatatc gcggaatggg ctgggatcgt
      721 ccagcaggac taatggtacg ggctctcccc tttgcaaaac atactcagcc gcacaatacc
      781 aatgggtggg cgaggtccgc aaattcagac agtccagcga atgaggttgg ttagtcgtca
      841 ccaccaaatc tacttcctgc gatttaacca tgtccaccat ataggcgttg cgttttaccc
      901 gtacatcaag cgcgagtttc ggataaaccg agctgattcg gctaagcaaa aaaggcagga
      961 tagtatcagc tgattcatca gaagcgccga ttgttaacac tccctgaaga ttactgaaca
     1021 ttaatgatga acacgcctca tcattaaaac gcaggatttt tctggcgtac cccagaagct
     1081 ggataccgtg ttcgctcaaa agtttgttac gaccatggcg ggcgaacaat tcctttccca
     1141 cgagttgctc aagacgctgc atttgctgac tgaccgcaga ctgagtacga cataccgccg
     1201 ccgccgccgc ggcgaaggtg ttcagatcgg caacggccac gaacgttctc agcagatcga
     1261 gatcgaggtt aattatcgga cgatttgcat ttatcataat ttttcactta ctgacgggtc
     1321 atatcgggct gacctggtta atgctgtgca ttcagaaaca agcaattcca tttgtaatgt
     1381 gcatccttcg cagtaccgcc tggttaccca ggtaaatgtt agaatgtaat tgaaaatacg
     1441 accaaaacac ttctcttact tactgatata ataccaaatg caactgatcg ggatatatca
     1501 aagagaatgt gtcatacctt
//
LOCUS       DAJVBX010000345         1517 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.347, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000345 DAJVBX010000000
VERSION     DAJVBX010000345.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1517
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.347"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(46..482)
                     /locus_tag="OPV72_004439"
                     /pseudo
     CDS             complement(46..482)
                     /locus_tag="OPV72_004439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308311.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(861..1286)
                     /locus_tag="OPV72_004440"
     CDS             complement(861..1286)
                     /locus_tag="OPV72_004440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="subtilase cytotoxin subunit B-like protein"
                     /protein_id="HCR9916556.1"
                     /translation="MKKKLKVLTLALASISSVCYAAMADYDTYVSNVQINNLSYGVYT
                     SGGKETQFFCIGLKHGSEAISINAMCKVDVYGNHKQGFDNMLNTAKYYYTTGGDVRIY
                     YKENVWRDPDFKSAFSSRELIAITTCSSSSYCMGPTVTN"
BASE COUNT          424 a          405 c          284 g          404 t
ORIGIN      
        1 gcagtccatg cttcgatgat gattgccgga gatttatctt ctctatcagc gcctccgggt
       61 ttcactgcgt gatgctgcag gaagttttct gtacagcgtc gacagccccc ataaataatc
      121 gttacctgct gtcgcggtac ttctgaccca atcagacgcc gggcctgcgc ctattgttcc
      181 aatgttagtt tcggtcgtcg gccaccatta cgccccctcg cccttgccgc ttccagtcca
      241 gcgcgggttc tttccacaat caattcacgt tccatttcag cgagtgcgcc catgacatga
      301 aagaagaatc gccccattgg cgtcgacgtg tctatgctgt cggtcaggct gcggacatta
      361 acgccgcgtt cgcgcaattc ttctaccaga acgaccagat gacgcatact gcgacccagg
      421 cgatcacgct tccatacaac cagtatgtcc ccttatgata acgtcctgac taaaaggaac
      481 aggcttcacg ggctggattt atccaacaaa gcgcgtagtg agtgcttccc gttagcctga
      541 atacgaaaaa ggccacgtaa atgcgcagcc tttatggtga gagttctaat cttaagaggc
      601 actccatcaa acaaaccacc cacagttgtc agaagcttga aggagtgctt tggggtgaca
      661 gtatctgcgg cattgttgcc acgaacaacg ttcccgcaaa tgctcaaaat acaatcccaa
      721 aatccgctcc agtaaacggt ctgaatatcg ttgccccaca gatcgctaca gccatacagg
      781 aacctgataa aggttcagac ataatcgtct caccaacaag attaagcctg ttctttagag
      841 cgtttaatac ccagcaacat ttaatttgtc accgtaggcc ccatacaata acttgatgag
      901 ctacaagtag ttatcgcaat taattccctg gaagagaatg cacttttgaa atcggggtcg
      961 cgccaaacat tctctttata atatatcctt acatcccccc ctgttgtata ataatacttt
     1021 gctgtattta gcatgttatc aaacccctgt ttatgattcc cgtacacatc cactttacac
     1081 atggcattga tactaatagc ttcactcccg tgcttcagtc cgatacaaaa aaactgagtt
     1141 tccttacccc ctgacgtata cacaccataa gacaggttgt taatctgaac attactcaca
     1201 tacgtatcat aatcagccat agctgcataa caaacactgg atattgacgc aagagcaaga
     1261 gtcagaacct ttaatttctt tttcataatc cactccaaca atatttacca tacttgtatt
     1321 tctatcgtaa acaagctcaa ctgcttcatg gatattttca attgggatag aatttacaga
     1381 tacatactca ctttgtaacc gcatcatcac tcgctcaaaa tgaccaaact ggataccaca
     1441 taactcaata taagcaacag acggcggaag gctgtagaaa ctattgtctg cacggattct
     1501 gtatctgtac aacctgc
//
LOCUS       DAJVBX010000346         1512 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.348, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000346 DAJVBX010000000
VERSION     DAJVBX010000346.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1512)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1512)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1512
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.348"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            7..>1512
                     /locus_tag="OPV72_004441"
     CDS             7..>1512
                     /locus_tag="OPV72_004441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoPQ-activated pathogenicity-related family
                     protein"
                     /protein_id="HCR9916557.1"
                     /translation="MFKRYLWKLCWLAFALVKRGESMKKIYLVVIVLFFISTKVYTLL
                     HNNIFFCRNSPECDLSHVLPDYREQISGTPLKYTLISTAPLAQVVVRHYELLSQHWSP
                     DDMVTPAQWRHNVDIYIPETAKEHHALVVVNNGINYEKGIQIPSKPVDFTQQTLASIA
                     RDTNTIVISVSDIPNQYLTFQDDKKPLKEDESVSRSWALFMEAPEQRELMPLNIPMVT
                     AISQAMRLAKKELTQWNINSFIITGISKRGWTTWLSAIADPDVEAIVPFAIDLLDIDA
                     SLEHIYQSYGGNWPITFYPYYQQGIDEKIKSPTFTQLRQIIDPLRYLNTIYQPRLAIP
                     KYIINASGDDFFVPDNTRFYYSKLPGVKSLRIVPNMNHYSINQFAEGSLVPFINRFQS
                     KKTLPQLIGLIHHHLLTVYFSEAPVKVVRWTANNPNARDFRYACGIRYQPLTIDIPAN
                     NKISITLNEPKTGWEATYIEATFNDGYVATSQVYITPDEKYPQTAPPSVNAA"
BASE COUNT          467 a          342 c          283 g          420 t
ORIGIN      
        1 tattgaatgt ttaagaggta tttatggaaa ttatgctggt tggcatttgc ccttgtaaag
       61 cgcggggaaa gcatgaaaaa aatatatctc gttgttatcg tactgttttt tatttctaca
      121 aaagtttata cactacttca taacaacatc ttcttttgtc gaaacagccc ggagtgtgat
      181 ttgtctcatg ttctccccga ctaccgggag cagatttcag gcacaccgct aaaatatacc
      241 ttaattagta cagctccatt agcacaggtg gtagtcagac actatgaatt attatcgcaa
      301 cactggtcgc cagatgacat ggtaacccct gcgcaatggc gacataacgt tgatatttat
      361 atccctgaaa cggcaaaaga gcaccatgct ttggtggttg taaacaacgg aattaattat
      421 gaaaaaggca tacaaatccc cagtaaaccc gttgatttta ctcagcaaac actggcaagc
      481 atcgcccgtg atacgaatac catcgtaata tcagtgagtg atatacctaa ccaatattta
      541 acctttcagg atgataaaaa accactgaaa gaggacgaga gcgtttcccg aagctgggca
      601 ttatttatgg aagcgccgga gcaacgtgag ttaatgcctt taaatattcc tatggtcact
      661 gccatatcgc aagcgatgag attagcaaaa aaggagttaa cgcaatggaa tataaattcc
      721 tttatcatta caggtatttc aaagcgtggg tggaccacct ggttgtcagc tattgccgat
      781 cctgatgttg aagcaattgt tcccttcgcc attgatctac ttgatattga tgcttcactt
      841 gagcatattt atcaatcata cggtggaaat tggcccatta cattctaccc ctactaccag
      901 caaggcatag atgagaaaat aaaatccccc acatttaccc agctaaggca aataatagat
      961 ccgttaagat atctcaatac tatttaccaa ccccgccttg caataccgaa atatattatt
     1021 aatgcaagtg gcgatgattt cttcgtacca gacaatactc gcttttatta tagcaaactt
     1081 cctggcgtaa aatcattacg tatagtgcct aatatgaacc actactcaat taaccagttc
     1141 gctgaaggaa gcctcgttcc atttattaac cggtttcaaa gtaaaaaaac attaccgcag
     1201 ttgatcggcc ttattcacca ccatcttctt acggtctatt tctcagaagc gccggtaaaa
     1261 gtcgttcgct ggacagccaa caatccaaat gcgcgtgatt tccgttatgc ctgtggcatc
     1321 cgctatcagc cgcttacaat agatattccc gccaacaata agatcagtat tacgttaaat
     1381 gaaccgaaga caggttggga agctacctat atcgaagcca cttttaatga tggctatgtc
     1441 gccacgagtc aggtttatat tacgcccgat gaaaaatacc cacagacagc accaccttcc
     1501 gttaacgccg ca
//
LOCUS       DAJVBX010000347         1476 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.350, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000347 DAJVBX010000000
VERSION     DAJVBX010000347.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1476
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.350"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            222..1151
                     /locus_tag="OPV72_004442"
     CDS             222..1151
                     /locus_tag="OPV72_004442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirK family antimicrobial peptide resistance
                     protein"
                     /protein_id="HCR9916558.1"
                     /translation="MTMQQSDMERYNPLLMLKEVMAQTPYRHKRWGERKFRYKFVLRC
                     LINPVTTIKYFNELCHLSQPRTLIIHRPLLPAKIQRPYLYTGLSIRCRAKAILEHYQF
                     VQSFPESKIKKILLSEEQILLAHLEGKNGALVDIYCGPCGYDREGELTLTLCFNDTPL
                     ARLSFSFIRHEGKQIALVAGLQGPSKHIGPQVIRNATKDCYGLFPKRMLYEAFATLMQ
                     ACNVDEIYAVSENNHVYRQLRYLFQKKKTFVASYSEFWESLNGVKKGALYHLPSQVMR
                     KAPESIPSKKRAEYRKRYHILDTIIQEVNSLSR"
BASE COUNT          446 a          315 c          303 g          412 t
ORIGIN      
        1 tatttaaaat aataaacacg gcattcgttt taatactacg ttcaggactc atcccactca
       61 ttagcagaaa atctattaaa aagcgcgttc aggcgtttta ttgctgccat tgataaactg
      121 tttaacaacg tcgtctgtac aggccttctt cgttgccttt acgtttaact caatcaggct
      181 accgtctcgg ttataagtct atcgagtagt agggacgtag tatgacgatg cagcaaagtg
      241 atatggaaag atataatcca ttattaatgt taaaagaagt catggcgcag acgccttatc
      301 gccataaacg ctggggagag cgtaagtttc gctataaatt tgtattacgt tgccttatta
      361 accccgtaac gacaattaaa tacttcaatg aattatgcca tctgtctcag cccagaacgc
      421 tgattattca tcgtccactg ttgccggcaa aaatccagcg gccctatttg tataccggac
      481 ttagcatacg ttgccgggca aaggctattc tggaacacta ccagttcgtt cagtcctttc
      541 cggaaagtaa aattaaaaag atccttctgt ccgaggaaca aatcttactc gctcacctgg
      601 aaggaaaaaa cggtgctctg gtagatatct actgcggtcc ctgtggctat gacagagaag
      661 gtgaactgac attaacgctg tgcttcaatg atacgccgtt ggcacgttta tcattttcct
      721 ttatccgcca tgaagggaag caaatagcgc tggttgccgg gttacagggg cccagtaaac
      781 atatcggccc acaagtcata cgtaacgcca ccaaagattg ttacggtctc tttcctaaac
      841 ggatgctgta tgaagcattt gcgacattga tgcaggcctg taatgtcgac gagatttacg
      901 cggtaagtga aaacaaccat gtttatcgtc aactcaggta cttattccag aagaaaaaaa
      961 cttttgtggc cagctatagt gaattctggg agtcgctaaa cggcgttaag aaaggtgcct
     1021 tatatcatct gccatcacag gtgatgcgta aagcgcctga aagtatcccc agcaaaaaac
     1081 gcgcagagta tcggaagcgc tatcatattc tggatacaat aatacaagag gttaacagcc
     1141 tctcccggta gaactatttc atacgcggat gtgcagatcc tgctaccgtt cagcggatct
     1201 ctttgaaatc tgtatcgcta ctggatggtt aaatacagaa tggcttgcga gtgaaaagcg
     1261 cggcattaaa ccgtcgcttt cattcatgct atgatcaaca tcttaatctt attcccttca
     1321 ccataacgtc atcgattagc atgttaacca ttaaatacaa gctaaacatt tgtcacattt
     1381 ttatttggtt gagcaaaaaa ataatacaaa atagaatttt cagtaagcta agtcaggagt
     1441 tttagtgaaa atacaagaag ttaagcgtat attaac
//
LOCUS       DAJVBX010000348         1454 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.351, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000348 DAJVBX010000000
VERSION     DAJVBX010000348.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1454
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.351"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(107..442)
                     /locus_tag="OPV72_004443"
     CDS             complement(107..442)
                     /locus_tag="OPV72_004443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCR9916559.1"
                     /translation="MKPLIFTLSLLALTGCTITRQAQVSEASPISGIVRLTYNQPLFF
                     TSRTDDYVSHGTATRECQQMGYADAVSFGQPVGTCSIYAGSLCLNTRFTLSWQCRGVS
                     VPQIMPLYY"
     gene            complement(773..1276)
                     /locus_tag="OPV72_004444"
     CDS             complement(773..1276)
                     /locus_tag="OPV72_004444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="non-heme ferritin-like protein"
                     /protein_id="HCR9916560.1"
                     /translation="MAAVGMVQKLNTPMNLEFYASNLYLHLSEWCSEHSLTGTATFLR
                     TQAQGNVTQMMRMFNFMKNAGATPIVKAIDVPGEELCSLEELFQKTLEDYQQRASTLS
                     RLADEAKALNDASTLDFLHTLEKEQQQDGVLLQTILEEVRSAKRAGLCLAQTDQHLLN
                     VVTYQHH"
BASE COUNT          369 a          336 c          367 g          382 t
ORIGIN      
        1 cagtgtatag cgtataaaaa taaaggaaag ccagcacctt catgctggca atagcgaccc
       61 tgcactctcc tctattgtac atggtgtcgg cgttaagcca gccgccttaa taataaagcg
      121 gcatgatttg cgggacggaa acgccccggc actgccagga gagggtaaat cgggtgttca
      181 gacacaacga gcccgcataa atgctacagg ttcctaccgg ctgaccaaac gaaacggcat
      241 cggcatagcc catctgctgg cattcgcgtg ttgcggttcc gtgagataca tagtcatctg
      301 tccgtgaagt aaaaaatagc ggctggttat acgtcaggcg cacgatgccg cttatcgggc
      361 tggcttcgct gacctgcgct tgtcgagtaa tggtgcatcc cgtcagggct agcagtgaaa
      421 gagtaaaaat aagaggcttc ataaaatcgc tccgacagtt cggtatcaga ccatgctacc
      481 tcgtgtcttg caccgtcaat ggctggaata acttacggat tcgccttgat taaaggtaac
      541 ggcaggggat ttacagcggg aacagaaaat gtgtgagcgt cttttcattt aatgaaactt
      601 tgtttcatta aatttgaatg tgtgttcgta aatgtgtagt gtaggcaaaa cgtcatgatt
      661 tatgcaggcg ccacctctgg caaacagacc agaaacggtg taggccggat aagctgcttc
      721 gcgttgctat ccggctaata acgtctcaat attgtcgctc ggggtgccgc tatcagtgat
      781 gctgataggt cacgacgtta aggagatgct gatcggtttg cgccaggcat agccctgctc
      841 gtttagcgct gcgaacttct tcgagaatag tttgtaaaag tacgccatcc tgctgctgct
      901 ctttttccag ggtatggaga aaatcgagcg ttgaggcatc attcagcgct ttcgcttcat
      961 ctgccagacg cgacagcgtg ctggcgcgtt gctgataatc ctccagggtt ttctggaaca
     1021 attcttccag agagcagagc tcttcacccg gaacgtcaat ggctttaacg ataggggtgg
     1081 cgccggcgtt tttcataaaa ttaaacatgc gcatcatttg cgtcacgttg ccttgcgctt
     1141 gggtacgaag aaaggtggct gtacctgtta aactgtgttc agaacaccat tcgcttagat
     1201 ggaggtaaag atttgatgcg taaaactcaa gattcattgg cgtgttgagc ttttgaacca
     1261 ttcctacagc tgccataaca atatccttat ttccagaaag tgttgatgtg catgacagac
     1321 gagaatgcaa cggatcgttg tcacattctt acctctatgc acaataaata ctcttagcag
     1381 aagaactccg ttccgccagt cccttatgcg atctcatttc ctgtttatcg atcggtaatg
     1441 agaatagcgc gtca
//
LOCUS       DAJVBX010000349         1454 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.352, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000349 DAJVBX010000000
VERSION     DAJVBX010000349.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1454
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.352"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..1114
                     /locus_tag="OPV72_004445"
     CDS             <1..1114
                     /locus_tag="OPV72_004445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MotA/TolQ/ExbB proton channel family protein"
                     /protein_id="HCR9916561.1"
                     /translation="AGEPKQCDFNLLMELDDNVSTARNQRLSFIMSCSNVSTLVGLLG
                     TFAGLSITIGSIGNLLSSPSDVGGDNASNTLNMIVTMVASLSEPLKGMNTAFVSSIYG
                     VVCAILLTSQSVFVRSSYSLVSTEIKKLKIISNRSNNKQRSLRVESETLVEFKELFKA
                     FFDNYLTVENLRTQDEEKKRVMLSDSFVTLQNRLLDNSAKLEQLSTLIDGYLVSNNEN
                     TKKLVDGVITITSRLSEGNTLLADNNARLEAMSTIQNIIDKKNDSIMASVDKCYQESF
                     SHGKTINDIAAGSADISHTLDGLRKEMDEDMNNVHLALSDLSATDKKIIANTKEISAE
                     MVSYRDTYMPLMEKITSMHQEIVKQRLLNKEEKNED"
     gene            1104..>1454
                     /gene="siiC"
                     /locus_tag="OPV72_004446"
     CDS             1104..>1454
                     /gene="siiC"
                     /locus_tag="OPV72_004446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-4 type I secretion system protein SiiC"
                     /protein_id="HCR9916562.1"
                     /translation="MKIKMFFLTTAFITQSTYASELPVIPLRDLVNAALTHQPSVAVS
                     YYETEKKNSDLDLSRAALYPTLDLTSGLNNNRKESSGTERNVENKVSLSYRITDFGVR
                     GANIRKSEYERDNSK"
BASE COUNT          478 a          256 c          304 g          416 t
ORIGIN      
        1 tgccggggaa cccaaacagt gtgatttcaa tttactgatg gaattagatg acaatgtgtc
       61 taccgcccgt aaccaacgat tgtcatttat tatgagctgt agcaatgtgt cgacgcttgt
      121 tggcctgttg gggacgtttg cgggtctgtc tattacgatt ggttcaatcg ggaacttatt
      181 gagctcgcca tcagatgttg gcggtgataa tgcaagtaat acactcaata tgattgtgac
      241 aatggtagcg tcgctttctg aaccattgaa agggatgaat accgcatttg tatcttctat
      301 ctatggtgtt gtttgcgcca tactcctgac ctcacaaagt gtttttgttc gcagctccta
      361 ttcccttgtt tctacagaga tcaaaaaatt aaaaatcata agtaacagat ccaataataa
      421 acaacgaagc ctgcgggttg aatcagagac gcttgtagaa tttaaagagt tgtttaaagc
      481 gttttttgat aactacctga cagttgaaaa cttacggacg caggatgaag aaaagaaacg
      541 agtgatgcta tcagatagct ttgtcacttt gcaaaaccga ctattggata actcagcaaa
      601 actggaacaa ctttctacgc tgattgatgg ttatctggta agcaataacg aaaataccaa
      661 aaaattagtt gacggtgtaa taacaattac ctctcgttta tctgaaggta ataccctgct
      721 tgctgataat aatgcacgac tggaggcaat gagtacaata caaaatatta tagacaaaaa
      781 gaatgattca ataatggcat cagttgataa atgttatcag gaatcttttt cacatggtaa
      841 gaccataaac gatattgccg ctggcagtgc cgatatttct catactctcg atgggctgag
      901 aaaagaaatg gatgaggata tgaataatgt tcatttagcg ctatccgatc tatcggctac
      961 tgataaaaag attattgcca atactaaaga gattagtgct gaaatggtta gctatcgtga
     1021 tacctatatg ccattaatgg aaaaaataac atctatgcat caggaaatag taaagcaacg
     1081 tttgttaaac aaggaggaaa aaaatgaaga ttaagatgtt ttttctgacg actgctttta
     1141 ttacacaaag cacatacgcc agcgagcttc cggtcattcc tctaagagat ttagttaatg
     1201 ccgcattaac gcatcagccc tctgttgctg tttcatatta tgagactgaa aagaaaaaca
     1261 gtgacttaga tctttcacgg gcagcacttt atcctaccct ggatctaacc tctggcctta
     1321 ataataacag aaaggagtcg tcaggtaccg agagaaacgt tgaaaataag gtatctttat
     1381 cataccgaat aacggatttt ggagtgaggg gggctaatat caggaaatct gaatacgaaa
     1441 gagataatag taaa
//
LOCUS       DAJVBX010000350         1451 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.353, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000350 DAJVBX010000000
VERSION     DAJVBX010000350.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1451
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.353"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..1329)
                     /locus_tag="OPV72_004447"
     CDS             complement(<1..1329)
                     /locus_tag="OPV72_004447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCR9916563.1"
                     /translation="MEGVQTMFAKFIDVIQTFLTEPAILIGILVGVGYALDKKTPIKI
                     ITGMISAMVGLMMVLFGGFQFSATFKPVAEAVSKAYGVHGYLMDSYAMKAATQIALGD
                     NFGYVGYVFVLAFFTNLILVLFGRYTGAKGIFLTGNTGVSHSQAVLWLIVFWLGFGWV
                     QSIVIAGVLTGVFWAFSTTLIVKPIAKVTNNAGFTIAHNQMLGLWFFSKFAHKFGDPE
                     KHDAENLKLPGWLAIFNHNVTAIAIVMTLFVGGFLLATGIDNVQLMAKGKPWYIYIIN
                     LGLQFSMYMVILLQGVRMMVGEINGSFKGWQDRFIPNAIPAVDVAALLPFSPNAATLG
                     FVFCTFGTIFSMGILLLIHSPIMVLPGFVPLFFSGGPIGVLANRMGGYRSVIICTFLL
                     GIIQTFGTVWAIPLTGLAKEGVGWTGIFDWATLWPAICELLKFIASTFHLG"
BASE COUNT          453 a          365 c          296 g          337 t
ORIGIN      
        1 accaagatgg aacgttgaag caataaattt cagtaattca caaatcgcag gccacagagt
       61 cgcccagtca aatattcccg tccagcccac gccttctttt gccagcccgg ttaaaggaat
      121 ggcccatacc gtaccgaaag tctgaataat ccctaacagg aaagtacaaa taataacgga
      181 acgatatccc cccattcggt tggctaatac gccgatggga ccgccggaaa agaagagcgg
      241 aacaaaacca ggcaatacca taatagggct atggatgagc agcaggatgc ccatggaaaa
      301 aatcgtgccg aaagtacaaa agacgaatcc cagcgtggcc gcgttaggcg aaaaaggtaa
      361 taaagcagca acatccacag ccggtatggc gttaggaata aagcgatcct gccatccttt
      421 aaacgaaccg ttaatttcac caaccatcat ccgcacgccc tgcagcaaga tgaccatata
      481 catagagaat tgcaggccca gattgataat atagatatac cagggtttgc ctttcgccat
      541 taactgtacg ttatcgatcc ctgtcgccaa tagaaaaccg ccaacgaaga gcgtcatcac
      601 aatggcgatt gccgtcacgt tgtggttaaa aatagctaac caaccgggaa gtttcaggtt
      661 ttcggcgtca tgcttttccg gatcgccgaa tttatgcgcg aatttcgaga aaaaccacag
      721 ccccagcatc tggttatgcg cgatggtaaa accggcgtta ttggtcactt tggcgatggg
      781 tttaacaata agcgtggttg aaaacgccca aaagaccccg gtcaataccc cggcaatcac
      841 aatggattgt acccaaccga accctagcca gaagacgatt aaccacagta ccgcctgtga
      901 atgagagacc ccggtattac cggtaagaaa tatacctttt gcgccggtat aacggccaaa
      961 taaaactaat atcaggttag taaaaaacgc cagtacaaaa acgtatccta catagccgaa
     1021 attatcgccc agcgctattt gcgtcgcagc tttcatggcg tatgaatcca ttaagtatcc
     1081 atgtacgcca taagccttgc tgactgcttc tgcaaccggt ttaaaagtgg ctgaaaattg
     1141 aaagccgcca aataacacca tcattaaacc gaccatcgcg ctgatcatac cggtgataat
     1201 ttttataggc gtctttttat ccagcgcata gccaacaccg actaatatcc caattaatat
     1261 tgccggttca gttaaaaacg tttgaataac atctataaat ttggcaaaca tcgtctgaac
     1321 gccctccata agcgtgtcta ttcgttgtca taattgaccc ctttactgac gttacgtatt
     1381 gcttcgctga tgctattgaa agttacccga taaaccacct tgtctaattt tgccttacac
     1441 gcactgtaat a
//
LOCUS       DAJVBX010000351         1419 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.354, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000351 DAJVBX010000000
VERSION     DAJVBX010000351.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1419
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.354"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..411)
                     /locus_tag="OPV72_004448"
     CDS             complement(<1..411)
                     /locus_tag="OPV72_004448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916564.1"
                     /translation="MRLKVKENITLWRNEGLIAYVALGFLCTFFMEVNALLPYYLQQS
                     IFFETLMSYMAFNTLFSLALSEIFFAMLVVICHNTKLERLTNSILQELHKRIMQGSFI
                     ISFLCFGIFLFCVMAFCIGSLTTNNNYYGKHVINF"
     gene            complement(485..817)
                     /gene="symE"
                     /locus_tag="OPV72_004449"
     CDS             complement(485..817)
                     /gene="symE"
                     /locus_tag="OPV72_004449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endoribonuclease SymE"
                     /protein_id="HCR9916565.1"
                     /translation="MTTVHSIADPCDPEVSPTNNRHLTVSYASRYPDYTRIPALTMKG
                     QWLEAAGFATGTEVDVRVMNGCIVLTAQQPQPEESELMQSLRQACKLSARKQKQVQAF
                     ISVMAGSK"
     gene            complement(1045..1335)
                     /locus_tag="OPV72_004450"
                     /pseudo
     CDS             complement(1045..1335)
                     /locus_tag="OPV72_004450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463383.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT          381 a          295 c          342 g          401 t
ORIGIN      
        1 aaaatttatg acatgtttcc catagtaatt attatttgtt gttagcgaac caatacagaa
       61 tgccatcaca caaaatagaa atattccgaa gcataagaag gatataatga aagaaccttg
      121 cataattctt ttgtgcaact cttgcaaaat actatttgtg agcctttcca gtttagtgtt
      181 atgacaaata actaccaaca tcgcaaaaaa aatctcagat aaagcaagcg aaaataacgt
      241 attgaaggcc atgtagctca tcagcgtttc gaaaaatata ctttgctgaa gatagtatgg
      301 caatagagcg ttgacctcca taaaaaaagt acatagaaat ccaagggcga cataagcaat
      361 taagccttca tttctccaaa gcgtaatgtt ttcttttact tttagccgca tggttttcct
      421 tcactcattg atatgaatta taattaaagc tggcaagggt tctttgccag cttattttat
      481 gcgtttactt agaacctgcc atcacgctga taaacgcctg cacctgcttt tgcttacgcg
      541 ccgacagctt gcacgcctgg cgcagcgact gcatcaactc gctttcttct ggttgcggct
      601 gctgtgccgt gagcacaata cagccgttca tcaccctcac atccacctcg gtaccggtgg
      661 cgaaaccggc ggcttccagc cactggccct tcatggtgag ggcgggaatg cgggtataat
      721 ccggataacg actcgcataa ctcacggtaa ggtgacggtt atttgttggg gatacttctg
      781 gatcgcacgg atctgcaata gaatggacgg tagtcatgat ggctattctc ctggaatagt
      841 gattgtgatg agcgatatgg ccgtgttccc gcacggccat atcgcgctaa atacctgtat
      901 ataacatcag taaataaaag aaaagtccag ctgaaaatag actgtaatgg gaatgttcag
      961 gaagaaactg gatatatttt tgatggttat gaatgcgggg gaataataaa aagcgcaccg
     1021 ggaaggtgcg caggaaaata agcgtcaggc ttttttacgc gaggtttttt taccaccgct
     1081 ggcggcgcgt tcggccttga ttttttccag cagggcggcg gcgctgtttt caccgctgat
     1141 aagacttggg ttttccgcac gccactgggc ggtaagctcg ccgcggaagg cctttgccag
     1201 gattgactgg gtgaggctgt tgacgcggtt cagggcgttg ttaacctgct tttcaatggt
     1261 gtcggcccag gcgaagagtt gttcgacgcg gcggacgatt tcgtgttgtt cttctaatgg
     1321 aggaactctg atgggataat ttgctagtgc ttttcctgta aggtgtttaa ttgtagttcc
     1381 tgtaaagagc tgagataagc taatgttatt tgaatcatt
//
LOCUS       DAJVBX010000352         1418 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.355, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000352 DAJVBX010000000
VERSION     DAJVBX010000352.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1418
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.355"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(1..1394)
                     /locus_tag="OPV72_004451"
                     /pseudo
     CDS             complement(1..1394)
                     /locus_tag="OPV72_004451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415044.4"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative allantoin permease"
BASE COUNT          440 a          354 c          285 g          339 t
ORIGIN      
        1 taagcaacga acgcaactat tacgcctaca aaccaggaca cgcgggataa aggctccata
       61 aatggtataa acttgccgcc taatgacaga atgactgcga ccagggtgac tgaaaatgca
      121 gtcaggttaa atccattatc ataatatttg taatcaccgc tggcggtgta tagctcatca
      181 agattaattt ttccacgcat taccacaaaa taatgagcta acattacgcc gattaccggg
      241 ccaagcatac cgccgataat atcgaggaac agataaatac tgtcctgatt ctccattaat
      301 ttccatggac aaatcagtag actgataata ctggcaatca ttacgccatt tttatagtta
      361 agctttgtcg gggtaagcgc cgcaatttga taccccgcag gtataatatt accggtggcg
      421 ttggttgaaa ttgtcgtcat cagaatcacc agcactgcaa agaatgaagc aaacaggctg
      481 tcccagcgct gcacaatatc cagcacgttc caggtatcca taccataatg aatactggct
      541 ccggcaataa tgcacacgct ggctacggcg aataatatat acgctacgat aagccccaat
      601 gtttgtccca atgcctgagc gcgaaatgaa tgcgcgtttt gcgtgaaatc ggacgcgctc
      661 accgctggcg cagcccagac ggcgactacg gcgttaatca ccactaggaa cagaaagccg
      721 ctgtgctctg ctttttgcac gcctgaaggc agatagtcca aaatcgggcc aatgccgacc
      781 agcgatattg cccaaatagc catgccgcca aagacaatat aaatacatgg attgaggata
      841 gcggtaaatt tatttaatac tttaccaccg ccaaaaccga tgccaacgtt aatgatccaa
      901 aaaattagaa aagtaattag ccctggcagt gaaaaaccca gcagcttgaa atctccgcct
      961 aatgtctaaa atcctggcca gatcttccca attaaaataa gaaatgccag cgatcccgcg
     1021 taacactgta agccgaacca cataattgcc gcgattcccc ctcgtaataa tccagggaat
     1081 agcgcgccgc ggacgccgta agaacctcgc aatatcatag caaaaggaac gccatatttg
     1141 ctgcctgccg cgccattcat taccatcgcc gccgcaataa ataatgcgct gataataatg
     1201 gccaacatga tattaaatgt tgatagcccc agtataaaaa aaccgccgac cataacgtaa
     1261 tttggcacgt tatgtacaga tcccatccat aaggtgaaat agttaaatgc tttccagttt
     1321 cgttgggttt ctgttttagg taataagtct tcgctataac cgcgttgctg atatagctct
     1381 ctttgatgtt ccataaatcc ctcttttcac gcatcgga
//
LOCUS       DAJVBX010000353         1416 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.356, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000353 DAJVBX010000000
VERSION     DAJVBX010000353.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1416
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.356"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            150..1388
                     /gene="alaC"
                     /locus_tag="OPV72_004452"
     CDS             150..1388
                     /gene="alaC"
                     /locus_tag="OPV72_004452"
                     /EC_number="2.6.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine transaminase"
                     /protein_id="HCR9916566.1"
                     /translation="MADSRPERRFTRIDRLPPYVFNITAELKMAARRRGEDIIDFSMG
                     NPDGATPPHIVEKLCTVAQRPDTHGYSTSRGIPRLRRAISHWYQERYDVDIDPETEAI
                     VTIGSKEGLAHLMLATLDHGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVEGVDFFNE
                     LERAIRESYPKPKMMILGFPSNSTAQCVELEFFEKVVALAKRYDVLVVHDLAYADIVY
                     DGWKAPSIMQVPGARDVAVEFFTLSKSYNMAGWRIGFMVGNKTLVSALARIKSYHDYG
                     AFTPLQVAAIAALEGDQQCVRDIAEQYKRRRDVLVKGLHEAGWMVEMPKASMYVWAKI
                     PEQYAAMGSLEFAKKLLNEAKVCVSPGIGFGDYGDTHVRFALIENRDRIRQAVRGIKT
                     MFRADGVLPSHPKPVEASTE"
BASE COUNT          311 a          349 c          405 g          351 t
ORIGIN      
        1 ttttacggtt gttcctcttt ttcgtcgcta aaaaatattt tcattagcct ctcgacagga
       61 agaaaatttt caggctattt tctaaaggag ccaccatcgt ggcagcgtcg ctcggacggt
      121 ccgggcgcta acgttaatct gaggatatta tggctgactc ccgccctgaa cgtcgcttta
      181 cgcgtatcga tcgccttccg ccctatgttt ttaacatcac cgctgaactc aaaatggctg
      241 cgcgtcggcg cggcgaagat attattgatt tcagtatggg taatcctgat ggcgcaaccc
      301 ctccccacat tgtcgaaaaa ctttgcaccg tcgcgcagcg tccggatacg cacggttatt
      361 ccacgtcccg cggcataccg cgtttacgcc gcgcgatttc tcactggtat caggaacgtt
      421 atgatgtcga tatcgatccg gaaaccgaag cgattgtgac catcggttcc aaagagggac
      481 tggcgcattt aatgctggcg acgctggatc atggcgatac ggttctggtg ccgaacccca
      541 gttacccgat tcatatctat ggcgccgtta tcgccggggc gcaggtgcgt tcggttccat
      601 tggtagaggg ggtggatttc ttcaacgagc tggagcgcgc tattcgcgaa agttatccga
      661 aaccgaaaat gatgattttg ggttttccgt ctaactctac ggcccagtgc gtcgaactgg
      721 aattttttga aaaagtggtc gctctggcta aacgttatga tgtgctggtg gtgcacgatc
      781 tggcgtatgc cgatatcgtg tacgacggct ggaaagcgcc atccattatg caggtgcccg
      841 gcgcgcgcga cgtggcggtc gaatttttca cactgtcgaa aagctataat atggcgggct
      901 ggcgtattgg gtttatggtg ggcaataaaa ccctggtcag cgcgctggcg cgcattaaaa
      961 gttatcacga ttatggtgct tttaccccgc ttcaggtggc ggctatcgcc gctctggaag
     1021 gcgatcagca gtgcgtgcgc gatatcgccg agcagtataa gcgtcgtcgc gatgtgctgg
     1081 tgaagggact gcatgaggcg ggctggatgg ttgaaatgcc gaaagcctca atgtacgtct
     1141 gggcgaaaat cccggagcaa tatgcggcga tgggatcgct tgagtttgcc aagaagctgc
     1201 tgaatgaggc gaaggtttgc gtttctccag ggataggctt tggtgactat ggcgacaccc
     1261 atgtacgctt tgcattaata gagaatcgcg atcgcattcg ccaggccgtc agagggatta
     1321 aaacgatgtt ccgcgccgat ggcgtgctgc cgtcacatcc aaaacccgtt gaagcgagca
     1381 cggagtagaa aagcaaacag gagccccatg gctcct
//
LOCUS       DAJVBX010000354         1392 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.357, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000354 DAJVBX010000000
VERSION     DAJVBX010000354.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1392)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1392)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1392
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.357"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..624
                     /gene="hlyE"
                     /locus_tag="OPV72_004453"
     CDS             <1..624
                     /gene="hlyE"
                     /locus_tag="OPV72_004453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415700.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin HlyE"
                     /protein_id="HCR9916567.1"
                     /translation="YILLFDEYNEKKASAQKDILIRILDDGVKKLNEAQKSLLTSSQS
                     FNNASGKLLALDSQLTNDFSEKSSYFQSQVDRIRKEAYAGAAAGIVAGPFGLIISYSI
                     AAGVIEGKLIPELNNRLKTVQNFFTSLSATVKQANKDIDAAKLKLATEIAAIGEIKTE
                     TETTRFYVDYDDLMLSLLKGAAKKMINTCNEYQQRHGKKTLFEVPDV"
     gene            complement(745..1176)
                     /locus_tag="OPV72_004454"
     CDS             complement(745..1176)
                     /locus_tag="OPV72_004454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HCR9916568.1"
                     /translation="MTIHKKGQAHWEGDIKRGKGTVSTESGVLNQQPYGFNTRFEGAQ
                     GTNPEELIGAAHAACFSMALSLMLGEAGFTPTSIDTTADVSLDKVEAGFAITKIALQS
                     KVAVADIDASTFDQIIQKAKAGCPVSQVLNAEITLDYQLNA"
BASE COUNT          405 a          286 c          304 g          397 t
ORIGIN      
        1 tatattttac tatttgatga atataatgag aaaaaagcat cagcccagaa agacattctc
       61 attaggatat tagatgatgg tgtcaagaaa ctgaatgaag cgcaaaaatc tctcctgaca
      121 agttcacaaa gtttcaacaa cgcttccgga aaactgctgg cattagatag ccagttaact
      181 aatgattttt cggaaaaaag tagttatttc cagtcacagg tggatagaat tcgtaaggaa
      241 gcttatgccg gtgctgcagc cggcatagtc gccggtccgt ttggattaat tatttcctat
      301 tctattgctg cgggcgtgat tgaagggaaa ttgattccag aattgaataa caggctaaaa
      361 acagtgcaaa atttctttac tagcttatca gctacagtga aacaagcgaa taaagatatc
      421 gatgcggcaa aattgaaatt agccactgaa atagcagcaa ttggggagat aaaaacggaa
      481 accgaaacaa ccagattcta cgttgattat gatgatttaa tgctttcttt attaaaagga
      541 gctgcaaaga aaatgattaa cacctgtaat gaataccaac aaagacacgg taagaagacg
      601 cttttcgagg ttcctgacgt ctgatacatt ttcattcgat ctgtgtactt ttaacgcccg
      661 atagcgtaaa gaaaatgaga gacggagaaa aagcgatatt caacagcccg ataaacaaga
      721 gtcgttaccg ggctgacgag gttatcaggc gttaagctgg tagtcgaggg tgatttccgc
      781 attcagaacc tgcgataccg gacacccggc ttttgctttc tggatgattt gatcgaaagt
      841 tgaagcatca atatctgcta ccgccacttt gctttgtagc gcaattttgg taatggcgaa
      901 gcccgcctcc accttatcaa gcgatacgtc agcggtggtg tcaatggatg tcggcgtaaa
      961 tccagcctct cccagcatga gtgatagcgc catggagaaa caggccgcat gtgcggcgcc
     1021 aattaactct tccgggttgg ttccctgcgc gccttcgaac cgggtattga atccatacgg
     1081 ttgttgatta agcacgccgc tttctgttga tacagtacct ttaccccgtt tgatgtcgcc
     1141 ttcccagtgt gcctgacctt tcttatggat tgtcattttt gctctcctgt tggctcaaaa
     1201 aataaagtat agactatgct gataatctgc gttgttcatg ccgatggatg tagcatgttg
     1261 tcgattaccc gcacttcaga tatagaaaat agttgtatgc tttttcagtg atggatatta
     1321 aaccaacagg cctccctttc tttaaagaat atatccctcc ttttatcctt actttttctt
     1381 ccggaagcgt at
//
LOCUS       DAJVBX010000355         1382 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.358, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000355 DAJVBX010000000
VERSION     DAJVBX010000355.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1382)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1382)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1382
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.358"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..341
                     /locus_tag="OPV72_004455"
     CDS             <1..341
                     /locus_tag="OPV72_004455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCR9916569.1"
                     /translation="NKLPDLRGEFIRGWDDGRGIDAARALLSIQNGMLEKHRHIVVAN
                     DGYDTKDEWELATIFKKTYTQGRGLDATNTGGSLIPSPTLHSRGSIGNTGGSETRPRN
                     IAFNYIVRAA"
     gene            complement(348..965)
                     /locus_tag="OPV72_004456"
     CDS             complement(348..965)
                     /locus_tag="OPV72_004456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001556994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HCR9916570.1"
                     /translation="MNNAAAVLDQNGIAITAGDITVYNYDAENREYLSATVEYLAYGV
                     GIPAHSCIDAPPEKRPGFAVCRDTDQNIWKYVPDHRGETVYSTENGNAVQITQPGDYP
                     PDTTVKQPATIYDVWDGETWVTDAGRQHAAELEAAGAHRQQLEEQAMASVELINLKLR
                     AGRRLTPQETEKLNAVLDFIDVLNATDISTAPDINWPEMPLAAAS"
     gene            complement(965..1363)
                     /locus_tag="OPV72_004457"
     CDS             complement(965..1363)
                     /locus_tag="OPV72_004457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HCR9916571.1"
                     /translation="MYPKLAKAYPTNKLPDLRGEFIRGWDDGRGIDSGRSLLNAQSHS
                     VIDHIHYMELWTGEGLAANSTRAGTNPGILATYGDGGIVKTDESGVKVPSSLRAIGTR
                     GVYRLGANGGNTGTENRPRNIAFNYIVRAT"
BASE COUNT          351 a          328 c          331 g          372 t
ORIGIN      
        1 cgaataaatt accggattta cggggtgagt ttattcgtgg ctgggatgat gggcgaggaa
       61 ttgatgcggc acgcgcttta ttgagcattc aaaacgggat gttggaaaaa caccgccata
      121 ttgttgtagc taacgatgga tatgacacaa aagatgaatg ggagttggcc acgattttca
      181 aaaaaacata tacacaaggc agggggcttg atgccacaaa tacaggaggg agtttgattc
      241 catcaccaac gcttcattca cgaggaagta ttggtaacac aggtggtagt gaaacccgcc
      301 cccgcaatat tgcatttaac tatatcgtga gggcggctta gttatattca actggctgct
      361 gccagaggca tttccggcca gttgatatcc ggtgcagtgc tgatgtcagt cgcattaagc
      421 acatctatga aatcaagcac ggcgtttagt ttttccgtct cctggggcgt caatcggcgt
      481 ccggctcgta gtttgagatt tataagctca acagatgcca ttgcctgttc ctcaagttgc
      541 tgacgatgcg ctccggcagc ttccagttct gctgcgtgct gtcgtcccgc atctgtcacc
      601 caggtctcac catcccagac atcatagata gtagctggct gtttcaccgt cgtatcagga
      661 gggtaatctc ccggttgtgt gatttgcaca gcgttaccat tctctgtgct gtaaaccgtt
      721 tcgcctctgt ggtctggaac atatttccag atgttctggt cggtatcacg acagacagcg
      781 aagccggggc gtttttctgg tggcgcgtca atgcatgagt gagccggaat tccaacacca
      841 taagcgagat actcaacagt ggcagagaga tattcacggt tttcagcatc gtagttataa
      901 acggtaatat cgcctgcagt tatagcgata ccattctgat caagtactgc agcagcatta
      961 ttcattaagt agcccttaca atatagttaa acgcaatatt acgggggcgg ttttccgttc
     1021 ctgtattccc tccgttggca cctaatctat aaacaccacg agtgccaata gcacgtagtg
     1081 aagatggaac ttttacacct gactcatctg ttttaacaat cccgccatca ccgtatgtag
     1141 ccagtatacc agggtttgtt cctgcacggg tgctatttgc ggcaagccct tcaccagtcc
     1201 ataactccat atagtgaata tgatctataa ccgaatgtga ttgtgcatta agcaaggaac
     1261 gccctgaatc aattccccgc ccgtcatccc agccacgaat aaactcaccc cgtaaatccg
     1321 gtaatttatt cgtggggtaa gcctttgcca gtttggggta catttcagaa gaaaatgctg
     1381 cg
//
LOCUS       DAJVBX010000356         1382 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.359, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000356 DAJVBX010000000
VERSION     DAJVBX010000356.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1382)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1382)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1382
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.359"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..841)
                     /locus_tag="OPV72_004458"
     CDS             complement(<1..841)
                     /locus_tag="OPV72_004458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020803150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpnT protein"
                     /protein_id="HCR9916572.1"
                     /translation="MAKLNKKQLSLLKEMPAEQLMQIICDIAEDNGQAKSFLINEYLL
                     TPEESLKKAEAEYKRVIKTKRFYDYYEAAIFFEGLYRNVIFPLEKTVSTLPEKTEAFC
                     HDLLLSFDKVSEIADTSDGSWMDYYNGAVEIWLKSLSLQKDKSIDVIADKIISVLKGD
                     VYFNFDIFDKYKKELGYNVIRVLRESLLKTGDVNGAVELSLYIRDVDFIRQCFEKRKL
                     NQPEYIIKFAELLVDELCTEEAIQVLNKIKEDKSVDQAGLRDKWTEVLALALIEEGEI
                     QQAK"
     gene            1036..>1382
                     /locus_tag="OPV72_004459"
     CDS             1036..>1382
                     /locus_tag="OPV72_004459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004151472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HCR9916573.1"
                     /translation="MNKLSPEMPELQSMNITADNITKLKSLFPEAFNENGIDFDVLKQ
                     LLGENVDEKEERYGLNWHGKRQARQLALTPSRGTLRPCKDESVDWDNTKNLMIEGDNL
                     EVLKLLQKSYTGKV"
BASE COUNT          435 a          300 c          224 g          423 t
ORIGIN      
        1 tttttgcctg ctgaatctcg ccttcttcaa tcaacgccag agccaacacc tcagtccatt
       61 tatcacgaag ccctgcctga tcaactgatt tatcttcttt gattttattg agaacctgaa
      121 tggcctcctc agtacacagt tcatcaacca gcaactcagc aaacttaatg atatattctg
      181 gctgattcag ttttcttttc tcaaagcatt gcctgatgaa atcaacatcc ctgatataca
      241 gacttaactc aacagcacca ttgacatcac ctgtcttaag aagactttcc cttaaaacac
      301 gaataacatt gtatcccagt tcttttttat acttatcaaa aatatcaaag ttaaaataca
      361 catcaccttt aagtacggaa attattttat ccgctataac atcaatactt ttgtcttttt
      421 gtagggacag ggattttaac catatttcga cagcaccatt ataatagtcc atccatgatc
      481 catctgatgt atcagcaatt tcgctgactt tatcaaatga gagcagtaaa tcatggcaaa
      541 acgcctcggt tttttcaggc agcgttgata ccgtcttttc aagtggaaat atgacattcc
      601 tgtatagccc ctcaaaaaaa atcgctgctt cataataatc ataaaagcgt tttgttttaa
      661 ttaccctttt gtattcagcc tcagcctttt tcagtgattc ttctggagtt aacagatatt
      721 cattaataag aaaggatttt gcctgaccat tatcctctgc aatatcacaa attatttgca
      781 tgagttgttc tgcaggcatt tccttgagta aagaaagttg tttcttgttc agtttagcca
      841 tcatcacatc ctgataatgt ttggtagacg cagaaaagct aattgtacta acacgaggac
      901 agaacattca ataaaagcat taacataatg atttaaaaag aaatctgtag cacgctgttc
      961 attgatgaaa tgcactcttt accgtaaaat atcccccatc acacagtaac ctgatacaga
     1021 tacgtggaat ggtcaatgaa caaactttcg cctgaaatgc ccgaactgca atcaatgaat
     1081 atcactgctg ataacatcac caagcttaaa tcattgtttc ctgaagcctt taatgaaaac
     1141 ggcattgatt ttgacgtttt aaaacagctt ttgggtgaaa atgtagacga aaaagaagaa
     1201 cgctatggcc tgaactggca tggtaagcgt caggctcgtc agcttgctct taccccttcc
     1261 cgtggcacct tacgcccatg taaagatgaa agcgttgatt gggataacac caagaacctc
     1321 atgatcgagg gtgataacct tgaagtgtta aagcttcttc aaaaaagcta cactggaaaa
     1381 gt
//
LOCUS       DAJVBX010000357         1347 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.360, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000357 DAJVBX010000000
VERSION     DAJVBX010000357.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1347
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.360"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..229
                     /locus_tag="OPV72_004460"
     CDS             <1..229
                     /locus_tag="OPV72_004460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HCR9916574.1"
                     /translation="EFIDFLRVIFSENESDTDETLDPLLEYFEKITEYPGGTDLIYYP
                     ETESDGTPEGILNIIKEWRESQGLPCFKKSK"
     gene            472..750
                     /locus_tag="OPV72_004461"
     CDS             472..750
                     /locus_tag="OPV72_004461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001729069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HCR9916575.1"
                     /translation="MELKNNLEDYTEDEFIEFLNNFFEPPEELTGDELSKFIDNLLRH
                     FNKITQHPDGGDLIFYPSEEREDSPEGVIEELKRWRKSQRLPCFKENK"
BASE COUNT          440 a          204 c          320 g          383 t
ORIGIN      
        1 tgagttcatt gatttcttga gagtgatatt ttctgaaaac gagtcggata cagatgaaac
       61 attagatcca ttacttgagt attttgagaa gatcactgaa tacccaggtg gaacagatct
      121 tatctattat cctgaaacgg aaagtgatgg aacacctgag ggtattctga acataattaa
      181 agaatggaga gaatctcaag gattgccttg ttttaagaaa agtaaatgaa aatcaggtgt
      241 aggggaatgc ccagagttac tggcgcagtt tagtaaatcg aatcaaactt tgataaaaag
      301 aggtcgagcg ccttactcct tgataaggca acaagtcgga ggtaggtgga cttatgaaat
      361 tccccacgtt ggaaagatcc agtatggagg aatggtgttt gatgttgata accttatgat
      421 aaacactcct aaaaatcata tacgattgca taagtaaggt ttgaggtgaa aatggaacta
      481 aaaaataacc ttgaagatta tacagaagat gagtttatcg agtttttaaa taattttttt
      541 gagcctcctg aagagttgac tggagatgaa ttatcgaagt ttattgataa tcttctacgc
      601 cattttaata aaattactca acaccctgat ggcggggatt tgatatttta tccatcagag
      661 gaacgagaag atagtcctga aggagttatt gaagagctaa aacgctggcg gaagtctcag
      721 agactcccct gttttaagga aaataagtag cgatcagtgg tgaggagttt gtcaaccgga
      781 accgggatga taatgcagtg accgttaaaa ggcaaaaata tgtcagttaa gggagtaact
      841 atcaaaggca taattctgag tgtttttaca ctgaaccgta gtgccagagg atatatttat
      901 ctgacgcgaa tcgtatgaag tgatagcttt acgtacggtt tgtgagaggc tgtagggaaa
      961 gatcctacgg cctactcact aagagtctat ttttgtacat tgtttcatgt tctggaaaca
     1021 cgataaagta tgagcctgac gaactctcgc ccgctaaagt tccacgctgg aacctgacgg
     1081 ccaggagtcg gacatctttg cggtggcgaa tttacatccg ttcaaaaaaa tctaatgtaa
     1141 gagatagatg atatggctaa atatatattc ctctttatct ggattgtgac attttctgtc
     1201 agcgctggtg agcgaggata ttatttattc gtatggggta accctgaagg gaaggaatat
     1261 tttaaagaat atagagctga tgaaaggata tatgcggtca ataaatcctg ttggaatgaa
     1321 agagcgggga actctatacg aatagta
//
LOCUS       DAJVBX010000358         1329 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.361, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000358 DAJVBX010000000
VERSION     DAJVBX010000358.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1329
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.361"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            51..1037
                     /locus_tag="OPV72_004462"
     CDS             51..1037
                     /locus_tag="OPV72_004462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001636847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase"
                     /protein_id="HCR9916576.1"
                     /translation="MTETECSERCVDFLKETMFNYNSGEITLAALDNDHLTPSEAGSN
                     GIYEAFEHRLIDFLTTPATPATASGDESGAIDQTDTSQPAAIEAFINSPEFQKNIRMR
                     DIEKNKIGSGSYGTVYRLHDDFVVKIPINERGIKVDVNSPEHRNCHPDRVSKYLNMAN
                     DDKNFSRSASMNINGKDVTVLVSKYIQGQEFDIEDEDNYRMAEALLESRGVYMHDIDN
                     VGNILIKEGVLFFVDGDQIVLSQESRQQRSVSLATRQLEEQIKARYLVKLKQSETEGN
                     TEDIEYYKSLITELDELIGEEEQAPAPGRRFKLAAPEEGTLVAKVLKDELKK"
BASE COUNT          385 a          251 c          332 g          361 t
ORIGIN      
        1 cacatcaaga aaatatgtta ctactacaga tgttttatga tggaatgtta gtgaccgaga
       61 cggagtgctc tgagcgttgc gtcgattttt taaaagaaac gatgtttaat tataattccg
      121 gggaaattac gcttgccgct ttagataatg atcacctgac gccgagcgaa gcaggtagta
      181 atgggatcta tgaggctttt gagcatcgtt tgatagactt cctgaccacg cccgccacgc
      241 ccgccacggc gtctggtgat gagagcggcg ctattgatca gacagataca tcacaaccag
      301 cggcaataga ggcgtttatt aactcgccgg agtttcagaa aaatattcgc atgcgtgata
      361 ttgaaaaaaa taaaataggt agcggaagtt atgggacagt ctatcggtta catgatgact
      421 ttgttgttaa gattccaatt aatgagcggg gaataaaagt ggatgttaac tctccggagc
      481 atcgtaattg tcatcctgat cgtgtcagta agtatttgaa tatggccaat gacgacaaga
      541 atttttctcg ttcggcctcc atgaatatta atggtaaaga cgttacagtt ttagtttcaa
      601 aatatattca aggtcaggag ttcgatattg aagatgaaga taactatcga atggcggagg
      661 cgcttcttga atcccggggg gtttatatgc atgatataga taacgtaggt aatattctga
      721 ttaaagaggg ggtacttttc tttgtcgatg gcgatcaaat cgtgctgtca caagaatccc
      781 ggcaacagcg aagcgtttct cttgcaacaa ggcaactgga agagcaaatt aaggcccgtt
      841 acctggtaaa attaaagcag tccgagaccg aaggaaatac tgaagatatt gaatattata
      901 agtcacttat tacagaactt gatgagttaa tcggagagga agaacaggca cctgcgccag
      961 gaagacgttt taaactagcc gcgccggagg aagggactct tgtggctaag gtattaaagg
     1021 atgaattaaa aaaatagcat ttagttccgt tcttttctgc gaatcgccgg gggcacattc
     1081 gctacagatt taccaatcaa ttattgagag ttgctattcg cttaaaggtc gttcggggga
     1141 tctggacagc ctatagcgga gatgcaactc gccactaggg ttggcgatgc cgcgctgcca
     1201 tagtgggtga aatgccacgc gatggtgcaa cactattaac tcgccttgat ttttcccctc
     1261 ttcctgacaa gaaaaacctg gctttacgga tggtctcatg ccgtcgtatt agcgttgttc
     1321 ggcgtagta
//
LOCUS       DAJVBX010000359         1302 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.362, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000359 DAJVBX010000000
VERSION     DAJVBX010000359.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1302)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1302
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.362"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            181..1044
                     /locus_tag="OPV72_004463"
     CDS             181..1044
                     /locus_tag="OPV72_004463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000211445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916577.1"
                     /translation="MTTQKEMEEIRAALSWFDVRRYDGLKDLTLEQIYAELERRMLAY
                     KTRQQWETAGKDNQMQAIYHDATIRCGDVILKSDWISDNHRLSHSYAVRPMTRVQLFN
                     YGRAMYRLETSEQTDPVAVSSDYISEYLKQGGMNPANKMLIEIDLEEASSDDLAEHLK
                     VLIALWQKHLKTPKPPKRKFRFGHKTFERILDYKVIPLMDLISWEQLYNEGKNIPFTI
                     LADILHGNNGVRSSENIKDTDYDYAKSYLDNDEYFKVLNDFYIKNNMLKDWGIVDVIT
                     LNDKSSDKNKK"
BASE COUNT          470 a          252 c          256 g          324 t
ORIGIN      
        1 tgatgaaaaa caattggtta ttttttatta aataaatcat gtttagtcaa ggtgaaagca
       61 ctgacctcca aggtcactta ctgtgctcac accattttga aaacccgctc ctcttttcca
      121 ctttctctat catgttgaat gggctaacgt ttaggaaaca caaaagcaat cggtagaaca
      181 atgactacac aaaaggaaat ggaagaaatc agggcagcgt tatcttggtt tgatgtacgc
      241 cgatatgatg gccttaaaga cctcacctta gaacaaatct atgcagagct tgaaagacgg
      301 atgttggctt acaaaacaag acaacaatgg gaaacagcag gcaaagataa tcaaatgcaa
      361 gcgatatacc atgatgccac aatccgatgt ggtgatgtga tacttaaatc agactggatt
      421 tcagacaatc acagactgtc gcatagctat gctgtaagac caatgaccag agttcaattg
      481 ttcaactatg ggcgggctat gtatcggctg gagacttcag agcaaacaga ccctgttgca
      541 gtgagttccg actacatctc tgagtatctg aaacaaggag gcatgaaccc tgctaacaag
      601 atgctgattg aaattgactt ggaagaagcc agcagtgacg atctcgcaga acatctgaaa
      661 gtactgattg ctctatggca aaagcacctg aaaacgccta aacccccgaa acgaaaattt
      721 aggtttggtc ataagacctt tgaaagaata cttgattaca aagtcatccc tttgatggat
      781 ttgatctcat gggaacagct ctacaacgaa ggtaagaaca tacctttcac cattttagct
      841 gacatcctgc atggtaataa tggggtcaga agtagtgaga acatcaaaga tactgattat
      901 gattacgcga aaagttatct tgataacgat gagtacttca aggttttaaa tgatttctat
      961 attaaaaaca atatgttgaa ggattggggt atcgttgatg tgataacact taacgataaa
     1021 tcctcggata aaaacaaaaa gtaaacacaa gggatgttca caacctgcga acatccctaa
     1081 aaagcgtatc cctccaaaaa tttccgcgaa actcacggtt ggtgaacatc cctagtttag
     1141 aaccagccaa aatcctagaa ttatctccat cgaacaacat actaaaaaac gaaatatcca
     1201 agatattacg taaaaaaaac aggagataat atggttcaaa acaaaacaga taaacatccg
     1261 aaactgattc gtttgccaga agtaaaaaga agaacagggt tt
//
LOCUS       DAJVBX010000360         1291 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.363, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000360 DAJVBX010000000
VERSION     DAJVBX010000360.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1291
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.363"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            44..685
                     /locus_tag="OPV72_004464"
     CDS             44..685
                     /locus_tag="OPV72_004464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916578.1"
                     /translation="MKLDTRLTSSALTLALAAVVIPFTADWQLPLLNGVVVRWIENGQ
                     ALWLLFGALFTAWYIRPLSRPEGAKQFWLWAVVWWVVLLGRSTSWGRDYFPDEPRMLF
                     RTISVLLIAALVLPVLFFAGLRKEIVRRLRDVPLPLWLFTVTACSYLISDTVEHHRWL
                     SPIFLHNARYTDLIEELYEVPFMIGLFMVTVGFMQQDKQDECTALELTPYHAK"
     gene            999..1247
                     /locus_tag="OPV72_004465"
     CDS             999..1247
                     /locus_tag="OPV72_004465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HCR9916579.1"
                     /translation="MGILSWIIFGLIAGILAKWIMPGKDGGGFFMTIILGIVGAVVGG
                     WISTFFGFGKVDGFNFGSFAVAVIGAIVVLLIYRKIKS"
BASE COUNT          317 a          254 c          345 g          375 t
ORIGIN      
        1 aaacttatga ttgggtatta aaaaccagaa gagtcttatg atcatgaaac tcgatacccg
       61 attaacttcg tcagcactta ctcttgcgct tgccgctgtg gtcatcccgt ttacggcgga
      121 ctggcaattg cctttgctta acggcgtggt ggtccgatgg attgaaaacg gacaagcgtt
      181 atggttactg tttggggcgc tatttaccgc ctggtatata cggccacttt cccgtcccga
      241 aggggcaaag cagttttggc tatgggctgt tgtctggtgg gtggtgctgt tgggtagaag
      301 caccagttgg gggcgtgact atttccctga cgagccgcgt atgctgttca gaacgatttc
      361 agtgctatta attgctgcgt tggtattgcc agtcctgttt tttgccgggc tacgtaagga
      421 gattgttcgt cgtctgcggg acgttcctct gccattgtgg ctgtttaccg tgacggcatg
      481 ttcatatctg atttccgaca ctgtcgagca tcatcggtgg ttgtcgccga tattcctgca
      541 taacgctcgt tacacagatt tgattgaaga gctttatgaa gtgccattta tgatcggttt
      601 gtttatggtg accgtggggt ttatgcagca ggacaagcag gatgaatgta ctgcgctgga
      661 gctgaccccg tatcacgcaa aatagcgcgg ctgaaaaaga ccatgaattc gatatgggat
      721 agatagcagt tagcaaaaaa agcccgcact cggtgaggcg ggcaaataat actggaagca
      781 atgtgagcaa tgtcgtaccg aacaggtggg ttataaactc aaccactcgg tattgataaa
      841 gataatcgtt atcattaatg attgcaaccc tgatatttat gcgcttttat ccacgacgct
      901 aaaaggtgat ggatatcaca aacttcactt tcctgacgat gtgctattct ttttaacggc
      961 aaataaaccg ctaacgttaa gacataagtg aggaaaaaat gggtattctt tcatggatta
     1021 tttttggact tattgcgggt attttggcta agtggatcat gccaggtaaa gatggcggcg
     1081 gattctttat gacgatcatt ctggggatcg tcggtgcggt agtcggagga tggatcagta
     1141 cgttctttgg ctttggcaaa gtggatggtt tcaacttcgg cagctttgca gtcgcggtga
     1201 tcggcgcgat tgttgtgctg ttaatctaca gaaaaatcaa aagctaaacg cagaactttc
     1261 agagataata aaggctacga caggtagcct t
//
LOCUS       DAJVBX010000361         1288 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.364, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000361 DAJVBX010000000
VERSION     DAJVBX010000361.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1288
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.364"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            186..1286
                     /gene="chaA"
                     /locus_tag="OPV72_004466"
     CDS             186..1286
                     /gene="chaA"
                     /locus_tag="OPV72_004466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-potassium/proton antiporter ChaA"
                     /protein_id="HCR9916580.1"
                     /translation="MTHACEAVKTRHKETSLIFPVLALVVLFLWGSSQSLPVVIGINI
                     LALIGILSSAFSVVRHADVLAHRLGEPYGSLILSLSVVILEVSLISALMATGDAAPTL
                     MRDTLYSIIMIVTGGLVGFSLLLGGRKFATQYMNLFGIKQYLIALFPLAIIVLVFPMA
                     LPQANFSTGQALLVALISAAMYGVFLLIQTKTHQSLFIYEHEDEGDDDNPHHGKPSAH
                     SSGWHTVWLLIHLIAVIAVTKMNASPLEALLTSMNAPVAFTGFLVALLILSPEGLGAL
                     KAVLNNQVQRAMNLFFGSVLATISLTVPVVTLIAWATGNDLVFGLGAPEMVVMVASLV
                     LCHISFSTGRTNVLNGAAYLALFAAYLMTIFA"
BASE COUNT          293 a          301 c          310 g          384 t
ORIGIN      
        1 acggaaatta actttttgtt atttaaacac tgttaaaaca agatacttgt tttactgacc
       61 ttgaaagaaa aaaatcgtct acgccgtaaa actacgtaaa aaaccactaa aaaaatacaa
      121 atttctgcta tttttacctt ctttactctt tccaaaatat taacacctgc acaagggaga
      181 cccacatgac acatgcctgt gaggcggtga aaacccgcca taaggagact tcgcttattt
      241 tcccggttct tgcgctggta gtgctgttcc tttggggaag tagccagtca ctaccagtgg
      301 ttattggcat caatatcctt gcacttattg gtattttaag cagcgcattt agcgtggtcc
      361 gtcatgccga tgtattagcg caccgactcg gcgaacccta cggatcgctt attttaagcc
      421 tgtccgtcgt tattcttgag gtgagtttaa tttccgcgct gatggctacc ggcgatgctg
      481 cgccaacgct tatgcgcgat acgctctact ctattattat gattgtcacc gggggactgg
      541 tcggtttttc gttgttgttg ggcgggcgta aattcgcaac gcaatatatg aatttatttg
      601 ggattaagca gtatcttatc gcgctatttc cgctggcgat tattgtgctg gtttttccca
      661 tggcattgcc gcaagccaat ttttctactg gtcaggcatt attggtcgcg ttaatttccg
      721 ccgcgatgta cggcgtattt ttgttgattc aaaccaaaac gcaccagagc ttatttatct
      781 atgaacatga agatgaaggc gatgatgaca atccacacca cggtaaaccc tccgcgcaca
      841 gtagcggctg gcatacggtc tggttactca ttcatttaat tgcggtcatt gccgttacca
      901 aaatgaatgc cagcccgctg gaggcgttgc tgaccagcat gaacgctccg gtcgccttta
      961 ccggtttcct ggtcgcgctg ttaattctct cgccggaagg actgggcgcg ctgaaggcgg
     1021 tactgaataa tcaggttcag cgggcaatga atctgttctt cggatcggtg ttggcgacga
     1081 tttcattaac cgtgccggtc gtcacgctca tcgcatgggc gacaggtaat gatctggtgt
     1141 ttggtttagg cgcgccggaa atggtagtga tggtggcctc gttagtgctg tgccatattt
     1201 cgttctctac cggacgcacc aacgtgctaa acggcgcggc gtatctggct ttatttgccg
     1261 cctatctgat gacgattttt gcctgata
//
LOCUS       DAJVBX010000362         1279 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.365, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000362 DAJVBX010000000
VERSION     DAJVBX010000362.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1279)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1279)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1279
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.365"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            135..737
                     /locus_tag="OPV72_004467"
     CDS             135..737
                     /locus_tag="OPV72_004467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCR9916581.1"
                     /translation="MQVIMFDRQSIFIHGMKISLQQHIPGISIQSVGQAEELWQKIES
                     APDALVMLDSGLDAEFCREVLQRTAQQFPEVKIIITAMDGSQKWLHEVMQFNVQVVVP
                     RDSDAETFVLALNTVARGMMFLPGDWLNSTELESHDIKALSARQREILQMLAAGESNK
                     QIGRALNISTGTVKAHLESLYRRLDVKNRTQAAMMLNESN"
     gene            complement(743..1099)
                     /locus_tag="OPV72_004468"
     CDS             complement(743..1099)
                     /locus_tag="OPV72_004468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme"
                     /protein_id="HCR9916582.1"
                     /translation="MPHISSRFSSACIAFIKQWQGLSLEKYRDRQGNWVIGYGHMLTP
                     DETLTFITPDQAEAFLLDDLNSCDMLLQNCLPELNDRFQRETLIALMFSIGHQRFLSL
                     INTDDISQPEISGLRI"
BASE COUNT          357 a          287 c          315 g          320 t
ORIGIN      
        1 tcataacctt tctcttcctc aaccaatgac tatcggtaaa atggcctata ccaaatggcg
       61 acttcttatt ttaccctacg ggtaataccc ttcctcatct tgagactatt atcttaccca
      121 ggtggagaaa agtaatgcag gtaatcatgt ttgacaggca gtcaatattt attcatggaa
      181 tgaaaatcag tttgcagcag cacattccag gaataagtat ccagagtgtc ggtcaggcag
      241 aagaactctg gcaaaaaata gaaagcgcgc cggatgcgct ggtcatgctg gatagcggcc
      301 tggatgctga attttgccgc gaggtgttac aaagaaccgc gcagcaattt ccggaggtga
      361 agattattat cacggcgatg gatggcagtc aaaagtggct gcatgaagtc atgcaattta
      421 acgttcaggt cgtggtgcca cgcgattctg atgccgaaac ctttgtcctt gcgctcaata
      481 ctgtcgctcg cgggatgatg tttttaccgg gggattggtt aaattcaacg gagctggagt
      541 cccatgatat aaaagcgtta agcgcccgcc agcgggaaat tttacagatg cttgccgcag
      601 gagaatcaaa taaacaaatt gggcgggcgt taaatattag taccgggacg gttaaagcgc
      661 atctggagtc gctttaccgg cggctggatg taaaaaatcg tacccaggcc gccatgatgt
      721 taaatgaatc gaattaacga cgttaaattc gcagtccgct tatttctggc tgtgaaatat
      781 catccgtatt gattaatgat aaaaaacgct gatgtccgat gctgaacatc agcgcaataa
      841 gcgtttcgcg ttgaaaccga tcgttaagtt ccggcaagca attctgtagc agcatatcgc
      901 agctattgag gtcatccagc aagaatgcct ccgcctggtc gggcgtaatg aacgtcagcg
      961 tctcatccgg cgtcaacata tgcccgtaac caatcaccca gttaccctgc cgatcgcgat
     1021 acttttccag cgacagaccc tgccactgtt taataaacgc gatgcaggcg gagctaaagc
     1081 gagatgaaat gtgcggcatg gcatctttct cataaaaagc gcgattataa agtgtgctgc
     1141 acgcgtggct agcggtcaga cggccaaacg caggcaggga aaaggtctat gccgttcagc
     1201 gtcacgccgc gttgacagaa tgaaaaactg atgtttttgg ttagtaaccg atcttcttat
     1261 aaatttgcaa tcattaaga
//
LOCUS       DAJVBX010000363         1267 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.366, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000363 DAJVBX010000000
VERSION     DAJVBX010000363.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1267
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.366"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..1084
                     /locus_tag="OPV72_004469"
     CDS             <1..1084
                     /locus_tag="OPV72_004469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HCR9916583.1"
                     /translation="HWDPATPALAFSINMGIIPLPMIWGGRMIDNGKGKQAIVIGGIL
                     FSLGFILSGFVDNLPMLFLTYGVIAGLGSGLAFTGNLNNILKFFPDRRGLASGIVLAG
                     VGVGTLLCTRLAEYFMAQTHDVSRALLYLGIVYLVVIFIVQFFIRSAPAKDSGGIKAS
                     PLDKDYRHMLKDLRFWLLFMILALGVFSGMVISSSSAQIGMTQYGLLSGALVVSLVSI
                     FNSIGRLFWGGLTDKLGGYNTLVIVYLFTCVCMLLLLFFNGNTSVFYFSALGVGFAYA
                     GILVIFLGLTSQNFGMRNQGLNYGFMYFGFAVGAVIAPYVTSAIAKYTGSYNTVFILT
                     TVLLLIGVVLTLITKKYVATVLAKIH"
     gene            1106..>1267
                     /locus_tag="OPV72_004470"
     CDS             1106..>1267
                     /locus_tag="OPV72_004470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HCR9916584.1"
                     /translation="MKIAIAGAGAMGCRFGYMLLEAGHDVTLIDGWQEHVDAIRSKGL
                     FVETETTQKY"
BASE COUNT          272 a          252 c          337 g          406 t
ORIGIN      
        1 tcactgggat ccggctacgc cggcgttagc attctctatc aatatgggga tcattccttt
       61 accgatgatt tggggcggga gaatgatcga caatggtaaa ggaaagcagg cgatagttat
      121 cggcggtatc ctgttttctt taggttttat cttgtccggg tttgtggata atttgcccat
      181 gctgttttta acctacggcg tcattgccgg gttgggatcg ggcctggctt ttacgggtaa
      241 tcttaataat attctgaaat ttttccctga ccgtcgcggt cttgccagcg gtatcgtact
      301 ggcgggtgtt ggcgtcggga cgctactttg cacccgcctg gccgaatatt ttatggcgca
      361 aactcacgat gttagtcggg cgttgttata tctgggtatt gtttatctgg tggttatttt
      421 tatcgtccag ttctttattc gtagcgcgcc agcaaaagat agcggaggaa ttaaagcctc
      481 gccactggat aaagactatc ggcacatgct gaaagatctg cgcttctggc tgctgtttat
      541 gattctggcg ctgggcgtgt tctctgggat ggtaattagc tcaagttctg cgcaaattgg
      601 tatgacgcag tacggtttac tgtccggtgc attagtcgtt agcctggtct cgatatttaa
      661 ctcgatcggt cgcctgttct ggggagggtt aaccgataaa ttaggcggct ataatacgct
      721 ggttattgtt tatcttttta cctgcgtctg tatgctgctg ctgttgttct tcaacggtaa
      781 tacttcggta ttctatttca gcgctctggg cgtgggcttt gcttatgccg gtatattagt
      841 tatcttcctt ggcttgacca gccagaattt tggtatgcgt aaccagggac taaactacgg
      901 ctttatgtat tttggttttg ccgtcggtgc ggttattgct ccttacgtca cgtccgctat
      961 tgcaaaatat accggaagct acaatacagt atttattttg acaacggtgc tattgcttat
     1021 tggagtcgtg ttgaccctga taacgaaaaa atatgtcgca acggttttag ccaaaattca
     1081 ttaatcagat aataaggaaa taaaaatgaa aattgcaatc gcaggtgcag gcgctatggg
     1141 atgtcgtttt ggctatatgc tgctggaggc cgggcacgac gtgacgctta ttgatggctg
     1201 gcaggagcat gtcgacgcta ttcgtagcaa ggggttgttt gtcgaaacgg aaacgactca
     1261 gaagtat
//
LOCUS       DAJVBX010000364         1128 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.367, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000364 DAJVBX010000000
VERSION     DAJVBX010000364.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1128)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1128)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1128
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.367"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(78..154)
                     /locus_tag="OPV72_004471"
     tRNA            complement(78..154)
                     /locus_tag="OPV72_004471"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(118..120),aa:Arg,seq:cct)
     gene            complement(559..1116)
                     /gene="pagC"
                     /locus_tag="OPV72_004472"
     CDS             complement(559..1116)
                     /gene="pagC"
                     /locus_tag="OPV72_004472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence membrane protein PagC"
                     /protein_id="HCR9916585.1"
                     /translation="MKNIILSTLVITTSVLVVNVAQADTNAFSVGYAQSKVQDFKNIR
                     GVNVKYRYEDDSPVSFISSLSYLYGDSQDSGSIESEGIHYHDKFEVKYGSLMVGPAYR
                     LSDNFSLYALAGVGTVKATFKEHATQDGDSFSNKISSRKTGFAWGAGVQMNPLENIVV
                     DVGYEGSNISSTKINGFNVGIGYRF"
BASE COUNT          327 a          263 c          231 g          307 t
ORIGIN      
        1 aactgaagtg gtcagtggga gtcgaaccca catcatcagc ctgacactga ggtaataaca
       61 ttatacgata accacattgg accgccaccg aggcctcgaa cctcgcacca tcaacttagg
      121 aggttgatgc tctatccagc tgagctagtg gcggctgggg acttctgcca ggcgcaaaaa
      181 aggtgctctc ctagataaaa tacatacctt gctacttttt agtagtcgtt caacggcagg
      241 tacaatatgc gaaggcgatc acaaaatctt gatgacattg tgattaattc caggaaaatt
      301 tttcagagtg aatcctgtga gatctagcgt tatttacacc agattttcct tcctgcttat
      361 cacctacctg agcaaccttg attgcttacc acaatccttt atctgtgctt atgctggtga
      421 gatattatgt acagcgtcac tatgacgaag agagtatgac gaagagagaa aagacaggca
      481 ggtacgtgtt actggtaaag aagccctgtt ttgtaactgg cggtgcggaa ggcgaacctt
      541 ccgcatagct tatgcttttc agaaacggta tccaattccg acgttgaagc cgtttatttt
      601 tgtagaggag atgttgcttc cttcataccc aacatcgacg acgatattct ccagcggatt
      661 catctgtaca cccgcgcccc aggcaaatcc cgttttcctt gaggaaattt tgttagaaaa
      721 agaatcgcca tcctgagtgg catgttcttt aaatgtcgcc tttaccgtgc cgacacctgc
      781 cagcgcgtat aacgaaaaat tgtcagacaa tcgataggct ggcccaacca ttaaagaacc
      841 atatttcacc tcaaacttgt catggtaatg gataccttca gactcaatag acccggaatc
      901 ctggctgtct ccatataagt aacttagcga ggaaataaaa cttaccggag agtcatcctc
      961 ataacggtat ttcacattta cccctcggat atttttgaaa tcctgaactt tactttgtgc
     1021 ataccccacg gaaaaggcgt tagtatcggc ctgtgcaaca tttacaacca aaacgcttgt
     1081 agtaataact aaagtggata aaataatatt tttcataaca actcctta
//
LOCUS       DAJVBX010000365         1125 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.368, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000365 DAJVBX010000000
VERSION     DAJVBX010000365.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1125)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1125)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1125
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.368"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
BASE COUNT          318 a          257 c          218 g          332 t
ORIGIN      
        1 ggaaaatttc ggaaatttcg gattattgat cataagcaac tgatttataa gaaaaacaaa
       61 aagagaccga atacgattcc tgtttacggc aacaattgat ctttcccttt aaattcataa
      121 tgttacatat taattaggtg attttaacga ttagaacacg ttatttttga ttctaataga
      181 ttcaattagt tatcactttt tacgttttaa ttcggacgta tttcgggcca ttttgcgtat
      241 aaatctcccg accaaacaaa ctcactgccc aatacatcac tcccctcttc cattggggga
      301 ctcccgatgc caaataccca tgtagacgaa ggcttaatag tgatgccaac aaaagcgatc
      361 gcgaaaagtt gaacaggtgg ctagtttcag attaaacaca ttggttagtc atcctgaaca
      421 agtaaaatcc gccgcaactg gcagccattc aatactcgca ctatcgaacg atcgccagct
      481 tgccgcagcc cgttcttgca tacgatgtgg ctgcggttcc atcacatcag gaatgtgaaa
      541 atctggataa acctgccact taacctgaag caggtcttca tagcgggtgg tataccgagg
      601 cgaaagcatt tctcttaagg tcgccatata aaaacattct attacaacga gttatctcct
      661 cctgcctccg ccccggcgca aagctatagt ttttctatct ccttgtgaaa caaacaatta
      721 ttcttgctat agcgctgatt aacaatcgtt cgcgggcaac gtacattcag cgagtttcag
      781 agcttcctga cggaattccg ccggtgctgt ttccgggact tcttactggt tgatacagat
      841 cctgcctctt acttgagaat ttactcattt agccgtatgt ccattatggg tggataagat
      901 catttatcat cgtaagggtt gaaagcgata agttaaactt gtcctggctc aacaagggaa
      961 cccgactaat gatgagctct tcatcttcaa ggcgttttat gccttccagc aagaatagat
     1021 attaaatcga caactgctgc caggtcttgc aggcgcagtg gacaatcgtg tggtaacagc
     1081 ctgagtcatt tcttattttt ctcattcagc ataactgcgt cttct
//
LOCUS       DAJVBX010000366         1124 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.369, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000366 DAJVBX010000000
VERSION     DAJVBX010000366.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1124
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.369"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(107..631)
                     /locus_tag="OPV72_004473"
     CDS             complement(107..631)
                     /locus_tag="OPV72_004473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ail/Lom family outer membrane beta-barrel
                     protein"
                     /protein_id="HCR9916586.1"
                     /translation="MKRRSSFLVFLGLLLASPLALANDQHTVSFGYAQTHLSSLKNSD
                     SKDLRGFNFKYRYEFNETWGMLGSFTATRNEMENYTWKEGKLHKNGSDSVDYGSLMFG
                     PTYRFNDYVSLYGNAGIATMKFNKHSKEESFAYGAGVIFNPVKSISIDASWEASRFFA
                     VDTNTFGVSVGYRF"
BASE COUNT          339 a          253 c          195 g          337 t
ORIGIN      
        1 cttcctctta agattacctg actgattata accatcccta ctctgtagca acgccatatt
       61 atatttttag ttccttgcca taaacgtaac gcttatactt ttaatatcag aagcgataac
      121 ctacgctgac accaaatgta ttggtatcca cagcgaagaa acggcttgct tcccatgatg
      181 catcgataga tatactctta acaggattaa atattacacc agcgccgtag gcaaaggact
      241 cttcttttga gtgtttatta aatttcatcg tcgctatacc cgcattgccg tacaggctca
      301 catagtcatt aaagcgatat gttggtccaa acatcaaaga accatagtcc acagaatcgg
      361 aaccattttt atgcaatttc ccctctttcc aggtgtagtt ctccatttca ttgcgcgtcg
      421 cagtgaatga gcctaacatc ccccaggtct cattgaactc gtaacgatat ttaaaattaa
      481 agcctcgcag atctttgcta tcgctatttt tcaatgaact gagatgagtt tgtgcataac
      541 caaacgatac ggtgtgctga tcgttagcca aagctaaagg tgacgctaat aataaaccta
      601 aaaaaacaag gaacgaagac cgtcttttca ttaaaaccac tccatttttg atatataatt
      661 aaggcggtac cggaacttat ggcacacaaa tagcatttag attaagagca cctaatgcgc
      721 ttattaccag tcatgccaac tgcggaggta atataacctg atatattcga taatggatat
      781 gaaatcagtc ttacagagtt cttacttttt tattaatagc ggattcatag ttgcttcaga
      841 cccgatcctg gcatcgcatc cgtcaggcgg actgcgagag gttatcagcg agtatcagtt
      901 acctccctgt cgagtcaaaa attcataact cattgtttta tatgcatttt aattgattat
      961 tgagttaacc tttacccttg ccgagggcaa tttcgcaact cgctttctga cgcattcaga
     1021 caacattcag atctactgcg cggtacaaac gttataaagc tgccgattaa gagaataaaa
     1081 aaggttttct cacccacttt agatattcga atctcattag ccgc
//
LOCUS       DAJVBX010000367         1115 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.370, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000367 DAJVBX010000000
VERSION     DAJVBX010000367.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1115)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1115)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1115
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.370"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..837
                     /locus_tag="OPV72_004474"
     CDS             <1..837
                     /locus_tag="OPV72_004474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016505863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus outer membrane usher protein"
                     /protein_id="HCR9916587.1"
                     /translation="SFLLSVPLQKLTNHEMYATYQNSSSSKHDMNHDLGITGVAFDSQ
                     LTWQARGQIEDKSKNQKATFLNASWRGTYGEIGANYSHNEINRDIGMNVSGGVIAHSS
                     GITFGQSISDTAALVEAKGVSGAKVLGLPGVRTDFRGYTISSYLTPYMNNFISIDPTT
                     LPINTDIRQTDIQVVPTEGAIVKAVYKTSVGTNALIRITRTNGKPLALSTVLSLKNND
                     GVIQSTSIVGEDGQAYVSGLSGVQKLIASWGNKPSDTCTVFYSLPDKNKGQISFLNGV
                     CK"
     gene            834..1115
                     /locus_tag="OPV72_004475"
                     /pseudo
     CDS             834..1115
                     /locus_tag="OPV72_004475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077813.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin"
BASE COUNT          381 a          178 c          220 g          336 t
ORIGIN      
        1 agttttctac tcagtgtacc tttgcaaaaa cttacaaatc atgaaatgta tgctacatat
       61 caaaactcat cctcttcaaa gcatgatatg aatcatgatt taggtattac tggtgtggca
      121 tttgatagcc aattgacatg gcaagcaaga gggcaaatag aagataaatc gaaaaatcaa
      181 aaggctacat ttttaaatgc ttcttggcga ggtacttatg gggagatcgg agcaaactat
      241 agtcataatg aaataaatcg tgatattggg atgaatgttt ctggtggggt gattgctcat
      301 tcatcaggaa ttacgtttgg tcagagtata tcggatactg ctgcactggt cgaggctaaa
      361 ggtgtaagtg gggcaaaagt tctgggccta ccaggtgtta gaaccgattt tagaggctat
      421 acaatatcca gttatcttac tccatatatg aataacttca tatctataga tccaacaacg
      481 ttaccaataa atacggatat taggcaaact gatattcaag tagttcctac cgaaggtgct
      541 attgtaaaag ctgtatataa aacaagcgtg ggtactaatg cattaattag aattacaaga
      601 acaaatggaa agccactagc tcttagcaca gttctttcac ttaagaataa tgatggagta
      661 atccaatcaa catctattgt tggcgaagat ggtcaggcat atgtatctgg attgtcagga
      721 gtgcaaaaat taatcgcttc gtgggggaat aagccctccg atacttgtac agttttttac
      781 tctcttcccg ataaaaacaa aggtcagatt agctttttaa atggagtgtg caaatgaatc
      841 agtataattc gtcaatacct aagttcattg tctctgtttt tctgattgtt actggttttt
      901 tcagctcaac tattaaagca caagaactta aattaatgat taaaataaat gaggctgttt
      961 tttatgaccg tattacaagt aataaaataa taggtacggg gcatctattt aacagagagg
     1021 gaaaaaaatc ctcattagtt caagtttaga aaaaattaaa aataccccag gggcatatat
     1081 tattagaggt cagaataact cagcccataa gctta
//
LOCUS       DAJVBX010000368         1110 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.371, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000368 DAJVBX010000000
VERSION     DAJVBX010000368.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1110)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1110)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1110
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.371"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(118..973)
                     /locus_tag="OPV72_004476"
                     /pseudo
     CDS             complement(118..973)
                     /locus_tag="OPV72_004476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460296.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
BASE COUNT          265 a          277 c          260 g          308 t
ORIGIN      
        1 ttttcgtccg gcatgatgat ggtaacacta aaaaaagggg gattgcatca ctctgtagca
       61 aatcaagccc cttgacaggg tttctccatt atctttctac gcgccgtata gcgcttctca
      121 tcggcaacct aacctctgcg ccagactccc ctttgttgtt ttcacctcgc tggctaccgc
      181 ttcaggcaag ttagaccaca gcgtcagcac tggcttcgtt ttatgttcga tagcctccac
      241 ggtaacctga tagtcgcaaa aattcgccga acggggtgta ttctgatcca taataaacgc
      301 agcgtaattt ccttcacttt ttgacggcgc cgttccggtg aataaaacct tctagtaccc
      361 gctgggaatt tctaccgtcg catcttctgg caatgtggcg atatgccgct caaaaagggg
      421 ggccggtcac tacgtgcact acagatacat cagcctgttt ggcaagttcg cgcacccggt
      481 tttccagtgc agcccatgct ccctggttca gggcggattt ctgcggcgta atattcgata
      541 aataatttaa cgacggccag tccgaaacgc cgcccaatcc tgccaacggc gcctggtgtc
      601 ccctgtcgac ttttaatagc gtatgggcat ttttataggc cgaaggggcc aacgtatccg
      661 agggcggtaa atcggggtcc tgcgcccagt tccgcgggcg accgcttgcc tggctggtct
      721 ttgtcacgct ataggcaacc cagttggcaa atttcgtggc gctattatta ttgagcgtat
      781 agacatggcg atagattgtt tgttgacttc ctccttgagg acagccaacg ctacagttat
      841 caggttgctg aacgagtacg ttacgatggg gtaactcggg tgccgatgtt gtatcctggg
      901 gaggatacga tgtagtacat gcgcttaata atactacggg cagtaatttt agcagattaa
      961 tggttttatt cattttttct tccttaataa taactgccct aataattcag atggcaataa
     1021 tttggttata ttaccctgcc agccgttaga tgcgctcatc attaaagaca acactatcac
     1081 ggtaaaaatt aataacagat aaacatcgaa
//
LOCUS       DAJVBX010000369         1095 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.372, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000369 DAJVBX010000000
VERSION     DAJVBX010000369.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1095)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1095)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1095
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.372"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            461..1095
                     /gene="sopE2"
                     /locus_tag="OPV72_004477"
                     /pseudo
     CDS             461..1095
                     /gene="sopE2"
                     /locus_tag="OPV72_004477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460811.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-1 type III secretion system guanine
                     nucleotide exchange factor SopE2"
BASE COUNT          371 a          194 c          248 g          282 t
ORIGIN      
        1 acgccatgaa aagtcataat atataaaaat cagttaatta attgattttt agataaggat
       61 tacagtggcg gagaggtttg gcgtggcgac tttataggtt ttgaaaaagc ggctaactcg
      121 ctggcaggat aattggtagc cagcctgcga atgggggcaa aatcgtaaca acatcagcat
      181 aaataataat gttcatgaat gttttgtgtg acgcagcagt tgaattgaag tgatgttttg
      241 cctgttcagg attgtcccga taaaaatgtt cctcgataaa agtcgatcac cttgcgccga
      301 aaaaaaacag gctaagtgac agaagaacaa aatccatcag gaaaataaaa tttataaata
      361 tcaatgagta aaaatggttg tggagaaggt ggctattttt tgaaagcaag aaatataaac
      421 aaagtgtagc tatgcatagt tatctaaaag gagaactacc gtgactaaca taacactatc
      481 cacccagcac tacagaatcc atagaagtga cgttgaacca gtaaaagaaa aacaacggag
      541 aaggacattt ttgcaaaaag tattactgcc gttagaaata gctttatcag cctgtcgacg
      601 agtctgtcag atcgttttag cctgcatcaa caaacagaca taccgactac ccattttcat
      661 cgtgggagcg cctctgaggg tagggcagta ttaaccagta aaactgttaa agattttatg
      721 ctgcaaaagc tcaatagcct ggatatcaaa ggtaatgcga gtaaagatcc ggcctatgct
      781 cgtcagacat gcgaagccat attatcagcc gtgtacagta ataataaaga tcactgttgt
      841 aaattactca tcagtaaagg ggtcagtatt accccctttc tgaaagagat aggagaggct
      901 gcgcagaatg cggggctacc tagggagata aaaaatggtg tatttactcc aggtggggca
      961 ggggcgaatc cttttgtcgt ccccctcatt gctgcagcga gcattaaata tccgcatatg
     1021 tttataaatc ataatcagca ggtgtctttt aaagcgtatg ctgagaaaat cgttatgaaa
     1081 gaggttacgc cgctg
//
LOCUS       DAJVBX010000370         1011 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.373, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000370 DAJVBX010000000
VERSION     DAJVBX010000370.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1011)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1011)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1011
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.373"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            241..435
                     /locus_tag="OPV72_004478"
                     /pseudo
     CDS             241..435
                     /locus_tag="OPV72_004478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460211.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DinI-like family protein"
     gene            832..>1011
                     /locus_tag="OPV72_004479"
     CDS             832..>1011
                     /locus_tag="OPV72_004479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000480169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916588.1"
                     /translation="MFLTFPNVAITRDNRIDKLSENDLELIRDTAIQNGGRKIQVQLR
                     DLLYEVSNRAVEGDNN"
BASE COUNT          338 a          197 c          229 g          247 t
ORIGIN      
        1 gagatcgaga taaagcttta ttaacgaact ttaacgaact tcacagacca cttttgcccc
       61 atccatgccc cacacataat tttagtcaac gccagacccc atcagccctg cagggcaaat
      121 cgataacaaa cacgcccgca gtatgttccc caaaatttaa aaacaagtgg ttcatgcctt
      181 gacagacaaa accgccaaag caaaatactg tatataaaaa cagtggctgg cgaagcacgt
      241 atgttcgtag aactggttta tgacaagcgt aatgttgaag gactcgaagg ggccagcgag
      301 atcattctgg ccgaactgac gaagcggatg caccagattt tccctgatgc cgaagtgagg
      361 gtgaagccga tgcaggcaaa ctgcttgaat agtgatacca acaaaagcga tcgcgaaaag
      421 ttaaacaggt ggcttggctg gtttcagatt acgcgggtag gatcagatca ctccaaatac
      481 cgacgacata gaattaggaa ttcagtgatg aatcaatgat ggcaatacac tgttcagaat
      541 gccatcgcgt atatgcgagc acagtgcccg tattagagaa catcggagac gggaagtaaa
      601 gtatcggggt ctggtagacc aggctgatgc aacgaagcca gcctggccag tcatctgtaa
      661 ttggttgaga gggcggagtc ctgcgtacca tgagtaagat aatcgtctaa aaccgtaaat
      721 ttttaatgga ataagtctta atctgtacaa aggcatattg cttttgatat ataaaccccc
      781 tcaatataga cgtgcattta tatcaatgat tatttaaagg agtagtgaag tatgttctta
      841 acatttccta atgtagcaat aactcgagat aacaggatag acaaattatc tgaaaatgat
      901 ttagaactca ttcgtgatac ggctatacaa aatggcggaa gaaagataca ggtacaatta
      961 cgtgatttat tatatgaagt aagtaatcgt gctgttgaag gtgataataa t
//
LOCUS       DAJVBX010000371         1011 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.374, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000371 DAJVBX010000000
VERSION     DAJVBX010000371.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1011)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1011)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1011
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.374"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..>1011
                     /locus_tag="OPV72_004480"
     rRNA            <1..>1011
                     /locus_tag="OPV72_004480"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          254 a          235 c          318 g          204 t
ORIGIN      
        1 ggttgtaaag tactttcagc ggggaggaag gtgttgtggt taataaccgc agcaattgac
       61 gttacccgca gaagaagcac cggctaactc cgtgccagca gccgcggtaa tacggagggt
      121 gcaagcgtta atcggaatta ctgggcgtaa agcgcacgca ggcggtctgt caagtcggat
      181 gtgaaatccc cgggctcaac ctgggaactg cattcgaaac tggcaggctt gagtcttgta
      241 gaggggggta gaattccagg tgtagcggtg aaatgcgtag agatctggag gaataccggt
      301 ggcgaaggcg gccccctgga caaagactga cgctcaggtg cgaaagcgtg gggagcaaac
      361 aggattagat accctggtag tccacgccgt aaacgatgtc tacttggagg ttgtgccctt
      421 gaggcgtggc ttccggagct aacgcgttaa gtagaccgcc tggggagtac ggccgcaagg
      481 ttaaaactca aatgaattga cgggggcccg cacaagcggt ggagcatgtg gtttaattcg
      541 atgcaacgcg aagaacctta cctggtcttg acatccacag aactttccag agatggattg
      601 gtgccttcgg gaactgtgag acaggtgctg catggctgtc gtcagctcgt gttgtgaaat
      661 gttgggttaa gtcccgcaac gagcgcaacc cttatccttt gttgccagcg gtccggccgg
      721 gaactcaaag gagactgcca gtgataaact ggaggaaggt ggggatgacg tcaagtcatc
      781 atggccctta cgaccagggc tacacacgtg ctacaatggc gcatacaaag agaagcgacc
      841 tcgcgagagc aagcggacct cataaagtgc gtcgtagtcc ggattggagt ctgcaactcg
      901 actccatgaa gtcggaatcg ctagtaatcg tggatcagaa tgccacggtg aatacgttcc
      961 cgggccttgt acacaccgcc cgtcacacca tgggagtggg ttgcaaaaga a
//
LOCUS       DAJVBX010000372          987 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.375, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000372 DAJVBX010000000
VERSION     DAJVBX010000372.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 987)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 987)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..987
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.375"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            166..>987
                     /locus_tag="OPV72_004481"
     CDS             166..>987
                     /locus_tag="OPV72_004481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR9916589.1"
                     /translation="MMMKRAIIVSVLEQIEKNLEERIDIEKLVVITGYSRRSLQDFFK
                     EKCGVSIGKYIRQRKLSRSATLLKLTSQSVTDIAFRMGFDSVQSYSREFKKTFGVNPN
                     NYRKADFWDLRNLRPPYWLDCDGHYQFEICQLTSKEIFGFQTSHQIATNDLPKKASPI
                     KWKIIHETLRTWGENVYCLSSFKPDNTKDQVIAVSSFFGMEHNSVDGGKIPMSRVIKC
                     GKYAKFHFVGHKEQYQQFSNTIYMCILPKLNIIRREGEDIEYFHLASVQKQQNNES"
BASE COUNT          334 a          182 c          198 g          273 t
ORIGIN      
        1 gctttactgg caaaagccga tctccaagtg taaagtttat tcagaaacgt caagcaattt
       61 aaatctttct tgttttgcca gaaaagctaa caacccccca ctggtttaat aacaccgtat
      121 gtcaaacacc ttaaatgttt atattttcgg cttcaataaa gaggaatgat gatgaaaaga
      181 gccataatag tctcagtatt agagcaaata gaaaaaaatc ttgaagagag gattgatatt
      241 gaaaagttgg ttgttataac aggttattcg cgaaggagtt tgcaggattt ttttaaagaa
      301 aagtgtggcg tctctatcgg aaaatatatc agacaacgca agttgagcag aagcgccact
      361 ctgctaaagc tgacctctca gtcggtcaca gatatcgcgt tcagaatggg gtttgattca
      421 gtgcagtcct atagtcgaga gttcaaaaaa acatttggcg tcaatcccaa taactatcgc
      481 aaggctgatt tctgggatct cagaaaccta cggcctccct actggcttga ctgtgatggg
      541 cattatcagt tcgaaatttg tcagcttacg tcaaaagaaa ttttcggatt tcaaacatct
      601 catcagatcg caacaaatga ccttcctaaa aaagcgtcgc ctataaaatg gaaaatcatt
      661 catgagacgc tcaggacgtg gggcgaaaat gtgtattgtc tctcgtcttt taagccggat
      721 aataccaaag accaggtcat cgccgtaagc agtttttttg gtatggaaca taattccgtc
      781 gatggaggaa aaatacccat gtcgagggta ataaaatgtg gtaaatatgc aaaattccat
      841 ttcgttggtc ataaggaaca atatcaacaa ttttccaata caatatatat gtgtatattg
      901 ccaaaactga atattatcag aagagaagga gaagatattg aatacttcca tttggcatcc
      961 gtccaaaagc aacagaataa tgaatcc
//
LOCUS       DAJVBX010000373          972 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.376, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000373 DAJVBX010000000
VERSION     DAJVBX010000373.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 972)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 972)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..972
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.376"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(102..965)
                     /locus_tag="OPV72_004482"
     CDS             complement(102..965)
                     /locus_tag="OPV72_004482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCR9916590.1"
                     /translation="MRYSPEALMAFVEAVSCGSFSAAARRLRKSQSTISTAIAHLEAD
                     LGFSLFDRSSRQPVLTEEGKRVLSYVQAILSASDRLDEVALTLSGETETRLTFVLSDT
                     LHPDSLEELMAQFDRQFPHTEFECLIGENDDVIDLLQKGRAQIGLIEARDNYPTDIGA
                     TRLLVQSWMGVYVATTHPLASQTNLQWEQLHTWRELRLNTYLDSNANITRGPAWSAPN
                     YLLLLSMAVQGFGWCVLPCALVEEFAAEKPLAQLDVPGWPRAIAIDLLWNKKTPPGTA
                     GNWLRYHLQQK"
BASE COUNT          242 a          274 c          242 g          214 t
ORIGIN      
        1 caccgccata gtagagcatt gttaaaatta gttatcttga ttgtttaaaa aaagtgagtt
       61 ttatcacaaa ggaaatgacg ctgatttgac ggtggcgcag cttatttctg ctgtaaatgg
      121 tagcgaagcc agttccccgc cgttccgggc ggcgtcttct tgttccacaa caaatcaata
      181 gcaatcgccc tcggccagcc aggaacatcc agctgcgcca gcggtttttc cgccgcaaac
      241 tcttccacca gcgcgcaggg caatacgcac cagccaaatc cctgaaccgc catgctcaac
      301 agcaataaat agtttggcgc tgaccaggcc gggccgcgcg taatgttggc gttagagtca
      361 aggtaggtat tcagacgcag ctcgcgccag gtatgcagtt gctcccattg caggttcgtc
      421 tgcgacgcca acggatgcgt ggtcgccaca taaaccccca tccagctttg aacaagcaga
      481 cgcgtcgcgc caatgtctgt gggatagtta tcacgcgctt caatcaggcc tatctgggcg
      541 cgcccttttt gcagcaggtc gatgacatca tcattttctc cgatcaaaca ttcaaactcg
      601 gtatgcggga attgacgatc aaactgcgcc attaactctt ccagactgtc agggtgcagg
      661 gtatcagaga ggacgaacgt gagccttgtc tccgtctcgc cggataacgt cagcgccacc
      721 tcatccagac ggtcgctcgc cgataaaata gcctgaacat agctaagcac ccgttttcct
      781 tcttcggtca gaacgggctg gcgcgatgat cgatcaaata atgaaaatcc cagatccgcc
      841 tccagatgcg caatggcggt actaatggtg gactggcttt tacgcaggcg gcgcgccgcc
      901 gcagaaaacg agccgcaaga gacggcctca acaaatgcca ttaacgcttc aggtgagtaa
      961 cgcataacct at
//
LOCUS       DAJVBX010000374          964 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.377, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000374 DAJVBX010000000
VERSION     DAJVBX010000374.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 964)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 964)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..964
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.377"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..>964
                     /locus_tag="OPV72_004483"
     CDS             <1..>964
                     /locus_tag="OPV72_004483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein kinase"
                     /protein_id="HCR9916591.1"
                     /translation="VYKVLDLKLDLDLALKTPLPGLESKRFLKSAKIAAKINHHNIAK
                     TFDYVEDNGNIFLAEEFVEGENLEEKLRHFDFLDPHYGACILHNLAKGIMASHKADVI
                     HRDLKPSNVMVSGGVQISNLKITDFGIATLTQELFDEAAASGDLTRSTSGTIKGALPF
                     MSPELMFGKKGKPIEASTDIWPLGAMMFKLLTGDYPFGVYLDAAVNVKTKNRMEWPTF
                     MTANPQYQSLSQDLQKIVDKCLSYDSDKRPTAETLVKACETLCYLSEERHVGRVNNLI
                     QGGISGFIDGTPSNSFFSMESVYGSRYPNTSTRNTVCYSTFDGHP"
BASE COUNT          325 a          161 c          185 g          293 t
ORIGIN      
        1 gtatataaag ttttagatct aaagctggat ttagatttag ctttaaagac tccacttcct
       61 ggtttggaaa gcaaaagatt tcttaaaagt gccaaaatcg ctgcaaaaat aaaccatcac
      121 aatatagcaa aaacctttga ttatgttgaa gataatggca atatattttt agcggaagaa
      181 tttgttgaag gtgaaaacct tgaggaaaaa ttgcgccact ttgatttttt agacccacat
      241 tatggcgctt gtatactaca taaccttgct aaaggaataa tggcatctca taaagcagat
      301 gttattcata gagatttaaa accgagtaat gtaatggtgt ctggcggagt acaaatttcg
      361 aatctaaaaa ttacagattt tggaatagct acgctaacac aagaactttt tgatgaagct
      421 gctgccagtg gtgacctaac aagatcgacc tctggtacga taaaaggtgc tttacccttc
      481 atgtctcctg aattaatgtt tggtaaaaag ggtaaaccta tagaagcatc aactgatatt
      541 tggccattag gtgcaatgat gtttaaatta ttaacaggag actatccatt tggcgtttat
      601 ttagatgctg ctgttaatgt taaaacaaaa aatagaatgg aatggccaac ctttatgact
      661 gccaatccac aatatcaaag tttatcacaa gatctacaaa aaattgtaga taagtgctta
      721 agttatgact cggacaagag gcctacagct gaaacgcttg ttaaggcatg tgaaaccctt
      781 tgttatttat ccgaagaacg tcatgtcggt cgcgtcaata atcttattca aggagggata
      841 agtggattta ttgatgggac accttctaac tcctttttta gtatggaaag tgtatacggt
      901 tcgaggtacc caaacacctc aacaagaaat actgtttgtt attccacttt tgatggacac
      961 ccat
//
LOCUS       DAJVBX010000375          945 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.378, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000375 DAJVBX010000000
VERSION     DAJVBX010000375.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 945)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 945)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..945
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.378"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..888)
                     /locus_tag="OPV72_004484"
     CDS             complement(<1..888)
                     /locus_tag="OPV72_004484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCR9916592.1"
                     /translation="MANLYDLKKFDLNLLVIFECIYQHLSISKAAETLYITPSAVSQS
                     LQRLRTQFNDPLFIRSGKGITPTVTGINLHYHLENNLNSLEQTINIMNQSSLKKKFII
                     YSPQLLITQYAMKLVKYIRKDPQVEIEHHDILTTDELPEDLLAYRKADVVVSMAPLNN
                     RSIVCTHFNRLECILVCSENHPRLGDTATIDEILQESFTQLVSRATGMKEYHSLIDDV
                     LGERIIGLRSKSVMTIANSISSTELIGFLPQTFVDYYSSSIKLKKVATPFTIAPIQFY
                     LMYNRASLNNSGFAELIEYI"
BASE COUNT          280 a          162 c          205 g          298 t
ORIGIN      
        1 gatgtactca atgagctcag caaatccgct attattcagc gaagctctat tgtacataag
       61 atagaattgt ataggagcaa tggtaaaagg tgtggcgact tttttaagtt tgatagagga
      121 agagtaatag tcaacaaatg tttgtggtaa aaaaccaata agctccgtgg agctgatgga
      181 gttggcgata gtcatcaccg atttgcttct taaaccaatt attctctccc ccagcacatc
      241 atctataagt gaatgatact ctttcatacc ggttgcccgg gagacgagtt gcgtaaatga
      301 ctcttgtaga atttcatcga tagtggcggt gtcgcctagt cggggatgat tttcactgca
      361 aaccaggata cattctagcc tattaaagtg agtacaaaca atagaacgat tattaagtgg
      421 ggccattgaa accacaacat ctgctttgcg gtaggcaagc agatcttcag gcagttcgtc
      481 agtggtcaaa atgtcgtgat gttcaatttc aacctgtgga tctttgcgga tatatttaac
      541 taatttcatc gcatattggg tgatcaacag ctgtgggctg tagataataa attttttctt
      601 cagactggac tgattcatta tattaatagt ttgttccagg ctgttaaggt tattttctaa
      661 atgataatgt aaattaatgc ctgttacggt aggcgtaatt cctttgcctg agcgaataaa
      721 tagaggatca ttgaattgcg tgcgcaggcg ttgcaatgac tgactgacgg cagaaggtgt
      781 aatatagagt gtttccgctg ctttgctaat gcttaaatgt tgataaatac attcaaatat
      841 aaccaacagg ttaagatcaa attttttaag gtcgtaaagg ttagccatag tatcttcccg
      901 gcattatcat ggtatcttcc atgattatga cttaatctca ataat
//
LOCUS       DAJVBX010000376          921 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.379, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000376 DAJVBX010000000
VERSION     DAJVBX010000376.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 921)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 921)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..921
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.379"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            261..908
                     /gene="narP"
                     /locus_tag="OPV72_004485"
     CDS             261..908
                     /gene="narP"
                     /locus_tag="OPV72_004485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite response regulator protein NarP"
                     /protein_id="HCR9916593.1"
                     /translation="MPEVTPFQVLIVDDHPLMRRGIRQLLELDPAFYVVAEAGDGASA
                     IDLANRIEPDLILLDLNMKGLSGLDTLNALRRDGVTAQIIILTVSDSASDIYALIDAG
                     ADGYLLKDSDPEVLLEAIRKGANGGKVFSDRVNEYLRERERFGAQEDPFSILTERELD
                     VLHELAQGLSNKQIASVLNISEQTVKVHIRNLLRKLNVRSRVAATILFLQTRGMQ"
BASE COUNT          228 a          221 c          232 g          240 t
ORIGIN      
        1 catatgccac acttctgtta tgtcacattg tccgaaaaaa gcgtccagac cagtattcaa
       61 cttcagggag tattctgttt tctctcacaa caggttgttt tatcctttct atcgttcagc
      121 taatgactcg cctgtcacag gttttactac ttacccatgc actaattaag gtaaaattta
      181 cgcgcttgac aatgtggcaa atctggacga tttccgcgct gaaaacaata atcattctaa
      241 taaaactcag gagatatagc atgcctgaag taacaccttt tcaggtgctt attgtggacg
      301 accatccact tatgcggcga ggtattcgtc aattactgga actggacccg gctttttatg
      361 tcgttgccga agcgggtgac ggggcgagtg cgatcgatct ggcgaatcgc attgagcccg
      421 atctgatcct gctggatctg aatatgaaag gtctgagcgg gttagatacc ctgaacgcgc
      481 tacgccggga tggtgtgacg gcgcaaatta ttattcttac cgtctcggat tccgccagcg
      541 acatctacgc gctgatcgac gccggcgccg acggttatct gctcaaagat agcgatccgg
      601 aagtgctgct ggaggccatt cgcaaaggcg ctaacggcgg taaagtcttt agcgatcggg
      661 tcaatgaata tctgcgtgag cgtgaacggt ttggcgcgca ggaagatccc tttagtatcc
      721 tgaccgaacg agagttagat gtcttgcatg agctggcgca ggggctttct aacaaacaga
      781 ttgcgtcagt actgaatatt tctgagcaga cggttaaggt gcacattcgt aatctacttc
      841 gcaagctaaa cgtgcgctcg cgcgtcgcgg cgaccattct atttttacaa acacgcggaa
      901 tgcagtaaca agccaggccc g
//
LOCUS       DAJVBX010000377          904 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.380, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000377 DAJVBX010000000
VERSION     DAJVBX010000377.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..904
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.380"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            61..765
                     /locus_tag="OPV72_004486"
     CDS             61..765
                     /locus_tag="OPV72_004486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR9916594.1"
                     /translation="MKKMMNDAFAKDNNENLLHSFLFSQQAKPHAAIDALFSALLPFG
                     QPFTLGIGDEFYLQANDEHYIVLLESGIVSFCRDDNRLHISSSFAPSVVGMVDSYGAT
                     YNVPARPEHFLLAETVCSGRFVRLPDFIKIADECDLWHDVARCLAYRLMVMSARDREL
                     VGVDSYLKVRALLIEIWAYPQAYRENIIVLNFIQRRTGISRSRTMKILSELKKGGYIH
                     IDNGRLTALGKLPVAY"
BASE COUNT          235 a          177 c          213 g          279 t
ORIGIN      
        1 ttaatttaag tactttttga gaggttatac tgtggcgcta cattgagtag acaaccgtta
       61 atgaaaaaaa tgatgaacga cgcttttgct aaagataata atgagaattt attacactct
      121 tttctttttt ctcagcaggc taaacctcac gcggcgattg atgccttatt ttcggccttg
      181 ttgccatttg gtcaaccgtt tacgctgggt atcggcgatg agttttattt acaggccaat
      241 gatgaacact acattgtatt actggagtca ggaattgttt ctttctgtcg tgatgacaac
      301 cgactccata tatcttcatc gtttgcgcca tcggtcgtgg gtatggttga cagctatggc
      361 gctacctata acgttcccgc gcgcccggaa cactttttgc tcgcagaaac ggtttgtagc
      421 ggtagatttg ttcgcctgcc ggattttata aaaatcgccg atgaatgcga tttgtggcac
      481 gacgtggccc gttgtctggc ttaccgtctg atggtgatga gcgcgcgcga tcgtgaatta
      541 gtcggcgtcg attcttacct gaaagttcgg gcgctgctga ttgaaatctg ggcttatcca
      601 caggcctacc gggaaaacat tatcgtattg aattttattc aacggcgtac cgggatatcg
      661 cgcagtcgga ctatgaagat tctgtctgaa ctaaaaaaag gcgggtatat ccatattgat
      721 aatgggcggc tgacggcact cggaaaactg ccagtggcgt attaatgcac tatacgcaac
      781 gatatattta catatctcaa ctgaatttgc ctgttatcgt taataaaatg ttttattgaa
      841 aattgttaag aagattattt ttaaaaagtc aatatgacta aaggagatag gccgaacggc
      901 tggt
//
LOCUS       DAJVBX010000378          882 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.381, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000378 DAJVBX010000000
VERSION     DAJVBX010000378.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..882
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.381"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..837
                     /gene="waaB"
                     /locus_tag="OPV72_004487"
                     /gene_synonym="rfaB"
     CDS             <1..837
                     /gene="waaB"
                     /locus_tag="OPV72_004487"
                     /gene_synonym="rfaB"
                     /EC_number="2.4.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide 1,6-galactosyltransferase"
                     /protein_id="HCR9916595.1"
                     /translation="LKETSPDIVICIDVISCLYANKARKKSGKQFTIFSWPHFSLDHK
                     KHAECITYADYHLAISSGIKEQMMARGISEQDISVVYNPVSIKTIIVPPPERDKPAVF
                     LYVGRLKFEGQKRVKDLFDGLARTTGEWQLHIIGDGSDFEKCQAYSRELGIEQRVIWY
                     GWQSAPWQVVQQKIKNVTALLLTSAFEGFPMTLLEAMSYGIPCISSDCMSGPRDMIKP
                     GLNGELYTPGAIDDFVGHLNRVISGEVKYQHDIIPGTIERFYDVLYFKNFNNAIFSKL
                     QK"
BASE COUNT          261 a          157 c          203 g          261 t
ORIGIN      
        1 ctgaaagaaa cgtcaccgga tattgtgata tgtattgatg tcatctcatg cctttatgcc
       61 aataaagcac gtaagaaaag tggtaaacag tttactattt tctcgtggcc gcatttttcg
      121 ctcgaccata aaaaacatgc agaatgtata acgtacgcgg attatcatct ggccatcagt
      181 agtggtatta aagaacagat gatggcacgg gggatctcag agcaagatat tagcgtcgtt
      241 tacaatcctg tctctattaa aacaatcatt gtgccgccgc ctgagcgcga taaacccgct
      301 gtatttctct atgtagggcg tcttaaattt gaagggcaga aaagagttaa agatttattt
      361 gatggcttag ctcgtacgac aggggaatgg cagctacata ttattggtga tggctcagat
      421 tttgaaaagt gccaggccta tagccgggag cttggtattg agcagcgtgt gatctggtat
      481 ggttggcaaa gcgcgccgtg gcaagtcgta cagcaaaaaa taaaaaatgt taccgcgtta
      541 ctacttacct ctgcatttga gggatttcct atgactctgc tggaagcaat gtcatatgga
      601 attccatgta ttagttctga ttgtatgtct ggtccgcgcg atatgattaa acccggtttg
      661 aatggtgagc tttacactcc gggtgctata gatgattttg taggacacct taatcgagtc
      721 atttccggtg aagtaaaata tcagcatgat attattcccg gcacgattga gcgattttac
      781 gatgtgctat attttaaaaa ttttaataat gcgatattct cgaaattaca aaagtgatca
      841 ctatgagcag aaaatatttt gaagaagaag tcattcaaca ga
//
LOCUS       DAJVBX010000379          882 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.382, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000379 DAJVBX010000000
VERSION     DAJVBX010000379.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..882
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.382"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..>882)
                     /gene="waaO"
                     /locus_tag="OPV72_004488"
                     /gene_synonym="rfaI"
     CDS             complement(<1..>882)
                     /gene="waaO"
                     /locus_tag="OPV72_004488"
                     /gene_synonym="rfaI"
                     /EC_number="2.4.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="lipopolysaccharide
                     3-alpha-galactosyltransferase"
                     /protein_id="HCR9916596.1"
                     /translation="AYGIDKNFLFGCGVSIASVLIANREKALAFHVFTDFFGSEDQQR
                     FDALAKQYATQIVVYLIDCERLKSLPSTKNWTYATYFRFIIADYFSDKTDRVLYLDAD
                     IACKGSIQELIDLNFAENEIAAVVAEGELEWWTKRSVSLATPGLVSGYFNAGFILINI
                     PLWTAENISKKAIEMLKDPEVVQRITHLDQDVLNILLVNKARFVDKKFNTQFSLNYEL
                     KDSVINPVDAETVFVHYIGPTKPWHSWGAYPVSQYFLRAKSNSPWSHCALLNPVTSHQ
                     LRYAAKHMFNQKHYTSG"
BASE COUNT          287 a          192 c          156 g          247 t
ORIGIN      
        1 tacccgaagt ataatgcttc tgattaaaca tatgctttgc cgcataacgt aactgatggc
       61 tagtgactgg atttaaaagt gcacaatgag accatggtga gttgctctta gcccgtaaaa
      121 aatattgtga cacggggtaa gccccccaac tatgccaggg cttcgttggt ccgatataat
      181 gaacaaatac agtctcagca tcaactggat taataactga atcttttaat tcatagttaa
      241 gactaaattg cgtattaaat tttttatcaa caaaacgcgc tttattcact aacaatatat
      301 ttaatacatc ctgatcaagg tgcgttatgc gctgtactac ctccggatct tttagcattt
      361 caatcgcttt cttagagata ttttctgcgg tccaaagagg tatgttaatt aaaataaaac
      421 cggcattaaa atagccagaa accaacccag gcgttgccag gctaaccgag cgcttagtcc
      481 accactccaa ctcgccttca gcaacaaccg ccgcaatctc attttcagcg aaattaagat
      541 caataagttc ctgaatactt cccttacatg caatatctgc atccagataa agcactctat
      601 ctgttttatc tgaaaaatag tcggcaataa tgaatctaaa gtatgttgca taggtccagt
      661 ttttggtact gggtagcgat tttaatcgct cacagtcaat gagataaaca acaatctgcg
      721 tagcgtactg ttttgctaat gcatcaaatc gctgctgatc ttcagagcca aagaaatcgg
      781 taaaaacatg gaaagctaac gccttctcac ggttagcaat gagaaccgat gcaatagaga
      841 caccacagcc aaaaagaaag tttttatcaa tcccataagc ta
//
LOCUS       DAJVBX010000380          880 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.383, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000380 DAJVBX010000000
VERSION     DAJVBX010000380.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 880)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 880)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..880
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.383"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            15..812
                     /locus_tag="OPV72_004489"
     CDS             15..812
                     /locus_tag="OPV72_004489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001523407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antimicrobial resistance protein Mig-14"
                     /protein_id="HCR9916597.1"
                     /translation="MHPDIVDYFMKRHNWHFKFFHYKEDDKIKGAYFICNDQNIGILT
                     RRTFPLSSDEILIPMAPDLRCFLPDRTNRLSALHQPQIRNAIWKLARKKQNCLVKETF
                     SSKFEKTRRNEYQRFLKKGGSVKSVADCSSDELTHIFIELFRSRFGNTSSCYPADNLA
                     NFFSQLHHLLFGHILYIEGIPCAFDIVLKSESQMNVYFDVSNGAIKNECRPLSPGSIL
                     MWLNISRARHYCQERQKKLLFSIGILKPEWEYKRMWSTPYFTGKSIC"
BASE COUNT          265 a          187 c          169 g          259 t
ORIGIN      
        1 gcggtagtat caatatgcac ccagatattg tggattattt tatgaagcgc cataactggc
       61 attttaaatt cttccactat aaagaagatg ataagattaa aggcgcctac tttatctgta
      121 atgatcagaa tattggcatc ctgacgcgca gaaccttccc gctatcttca gatgagatac
      181 ttattccgat ggcgccagat ttacgctgct tcttgcccga tcgtactaac cgactttcgg
      241 cgttgcatca gccacaaata cgcaatgcca tatggaaact cgccagaaag aaacaaaatt
      301 gtctggtcaa agaaacgttc tcttctaagt ttgaaaaaac acgccgtaat gaatatcagc
      361 ggtttcttaa aaaaggcgga agtgtaaaaa gcgttgctga ttgttcttct gatgaactga
      421 ctcatatttt tatcgagtta tttcggtctc gtttcggcaa tacttcatcc tgctatcccg
      481 ctgataacct tgccaacttt tttagtcaac tgcatcacct tctgtttggg catattcttt
      541 atattgaagg gataccctgt gcatttgata tcgtactgaa atctgaaagc cagatgaacg
      601 tctactttga cgtatctaat ggtgcaatta aaaatgaatg caggccactc agtcccggca
      661 gcatactaat gtggctaaat attagccgtg ccagacatta ctgccaggaa agacaaaaaa
      721 aattgctttt ctccatcggc atactaaagc ctgaatggga atataagcgc atgtggtcga
      781 ccccctattt taccgggaaa tcgatttgct aaaaagaaag cctggacgta aatatgtttt
      841 ttacgcccag gtttttcata aaccctgata aaatgataaa
//
LOCUS       DAJVBX010000381          869 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.384, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000381 DAJVBX010000000
VERSION     DAJVBX010000381.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 869)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 869)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..869
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.384"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..635
                     /locus_tag="OPV72_004490"
     CDS             <1..635
                     /locus_tag="OPV72_004490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF3251 domain-containing protein"
                     /protein_id="HCR9916598.1"
                     /translation="FLSGCDYFADKHLVEELKKQQKEQEAKINLLEKQQKEQEVKINL
                     PEKQQTTVINTTQKIAEVVGRVERKQRLFDYTELDPSQTHYFIINNGNIGLAGRILSI
                     EPIDNGSVIHLDLVNLLSIPVSNLAFNMTWGTKKPSEAKDLPRWRQLLLNTKMDSTIE
                     LLPGAWTNVTLTLKGVSPNNLKYLKIGIDMENVIFDSIQPINDTKKKPKK"
     gene            679..>869
                     /locus_tag="OPV72_004491"
     CDS             679..>869
                     /locus_tag="OPV72_004491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001680219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ESPR domain-containing protein"
                     /protein_id="HCR9916599.1"
                     /translation="MNRIFKVLWNAATGTFIVTSETAKSRGKKSGRRKLAVSALVGLS
                     SIMVSADALANAGNDTGSI"
BASE COUNT          316 a          182 c          172 g          199 t
ORIGIN      
        1 tttttttgtc tggttgtgat tacttcgcag ataagcacct tgttgaagaa ctgaaaaaac
       61 aacaaaaaga acaagaagca aagataaacc tgttagaaaa acaacaaaaa gaacaagaag
      121 taaagataaa tttgccagaa aaacaacaaa ctacggttat caacacgact caaaagatcg
      181 ccgaagtcgt tggccgcgtt gaacgcaaac aacggctatt cgactataca gaactggacc
      241 catcacaaac gcactatttt attattaaca acggcaatat cggattagcc gggcgtattc
      301 tatctattga gccaatagat aatggaagtg ttattcatct tgatttagtt aacttactca
      361 gcattcccgt atcaaacctt gcgtttaata tgacatgggg tacgaaaaaa ccttccgagg
      421 caaaagatct gcctcgctgg cgacaactcc tgctcaacac gaaaatggac tcgacaatcg
      481 aactcttacc gggagcatgg acaaacgtca cgctaacatt aaaaggcgta tcgcccaata
      541 atcttaagta tctaaaaata ggtattgaca tggagaatgt catattcgac agcatacaac
      601 ctattaatga tacgaaaaag aagccaaaaa aataatagcc attgatacaa ctattttaga
      661 aaaggaaagc acttattcat gaacagaata tttaaagtcc tctggaatgc cgctacggga
      721 acatttattg tcaccagcga gacggcaaaa agccgcggaa aaaaaagcgg ccgcagaaag
      781 ctggcggttt ccgcactcgt cggtcttagc agtattatgg tctctgcaga tgcgctggcc
      841 aatgcaggga acgataccgg cagcattaa
//
LOCUS       DAJVBX010000382          863 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.385, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000382 DAJVBX010000000
VERSION     DAJVBX010000382.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..863
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.385"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..169
                     /locus_tag="OPV72_004492"
     CDS             <1..169
                     /locus_tag="OPV72_004492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="subtilase cytotoxin subunit B"
                     /protein_id="HCR9916600.1"
                     /translation="KELLDQARYFYSTGQSVRIHVQKNIWTYPLFVNTFSANALVGLS
                     SCSATQCFGPK"
     gene            186..>863
                     /gene="artA"
                     /locus_tag="OPV72_004493"
     CDS             186..>863
                     /gene="artA"
                     /locus_tag="OPV72_004493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011233073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pertussis-like toxin subunit ArtA"
                     /protein_id="HCR9916601.1"
                     /translation="MKKLIFLTLSIVSFNNYAVDFVYRVDSTPPDVIFRDGFSLLGYN
                     RNFQQFISGRSCSGGSSDSRYIATTSSVNQTYAIARAYYSRSTFKGNLYRYQIRADNN
                     FYSLLPSITYLETQGGHFNAYEKTMMRLQREYVSTLSILPENIQKAVALVYDSATGLV
                     KDGVSTMNASYLGLSTTSNPGVIPFLPEPQTYTQQRIDAFGPLISSCFSIGSVCHSHR
                     GQRADVYN"
BASE COUNT          261 a          167 c          175 g          260 t
ORIGIN      
        1 taaagaactt cttgatcagg caagatattt ttacagtaca gggcaatccg taaggattca
       61 tgttcaaaaa aatatctgga cctatccgct ttttgttaat accttttcag caaatgctct
      121 tgtgggacta tcatcgtgca gtgcgacaca atgctttgga cccaagtaag aggggagaag
      181 aaataatgaa aaagttaata ttcttaacct tatctatagt tagctttaat aactatgctg
      241 tagattttgt gtatcgtgtg gactcaaccc cgccggacgt tatttttcgc gatgggtttt
      301 cactacttgg gtataaccgt aactttcagc aatttattag tggaaggtca tgtagtggtg
      361 gaagtagtga cagtcgctat attgcaacaa cctcaagtgt taatcaaaca tatgctatag
      421 ccagagcgta ctattctcgc tcaacattca aaggtaattt atacagatat cagattcgtg
      481 cagataataa tttctacagc ttgctcccat ccatcaccta tctggaaacg caaggtggtc
      541 actttaatgc ttatgaaaaa acgatgatgc gattgcaaag agagtatgtt tccacattat
      601 ctattttacc cgagaatatt caaaaggccg tggcgctagt ttatgatagc gcaaccggtc
      661 tagtaaagga tggtgtaagc acaatgaatg ccagttattt aggtttaagc actacgtcta
      721 atcctggtgt gatacctttt cttccggaac cgcagacgta tacccaacaa cgaattgatg
      781 cattcggccc attaataagt tcatgctttt caataggtag cgtatgtcat tcacatcgag
      841 ggcaaagagc tgacgtatac aac
//
LOCUS       DAJVBX010000383          841 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.386, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000383 DAJVBX010000000
VERSION     DAJVBX010000383.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 841)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 841)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..841
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.386"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..740)
                     /locus_tag="OPV72_004494"
     CDS             complement(<1..740)
                     /locus_tag="OPV72_004494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCR9916602.1"
                     /translation="MGSKGANKSFDYNLIKILDAVILSGNAAMAAKKLGITPAAVSLA
                     LKRLQSYYPEELFSRGKGGLIPTAKAVDIHQNFSQVMKLVDDTFLCNSKKDEAFQITL
                     LGSDIVESYYLSQLYNSDIFDRILINHFSVRNMSREHISELLFTAQGDLLISAEPLLE
                     SGIENQIIDSFKSFVCICSSKHMLSTLSQLSLHHFYSSRHALYQPGMGASVIYHDSEL
                     FKDELYYTGRRIVGYRSDSLNGLMSMIER"
BASE COUNT          266 a          194 c          153 g          228 t
ORIGIN      
        1 cgttcgatca tgctcatcaa accgttaagt gaatcactac gatagccgac aatacgcctg
       61 ccagtatagt aaagctcatc cttaaataac tcgctatcat gatatatcac tgaagccccc
      121 atccccggct gatataacgc atgacgcgaa gaataaaaat gatgtagcga cagttgcgag
      181 agggtactca gcatgtgttt actgctacag atacaaacaa atgatttaaa actatcaatg
      241 atttgattct ctatgccgga ctccagcaaa ggttcggcac taatcaacag atcgccttgc
      301 gcagtaaaca gaagttcgct gatatgctcc cgactcatat ttctgacgga gaaatgattt
      361 atcaaaatac ggtcaaatat atcgctgtta tagagctgag aaagataata gctttcaaca
      421 atatcactgc ctaataacgt tatctggaac gcttcatctt ttttgctatt acagagaaat
      481 gtgtcatcca ccagtttcat cacctgactg aaattttggt gaatgtcgac agccttagca
      541 gtggggatga gcccgccttt ccctctgcta aacagttctt ccgggtaata actctgcagg
      601 cgctttaacg ccagagaaac ggcagccggt gtaatgccta acttttttgc cgccatagcc
      661 gcatttcctg acaaaataac agcgtcaaga attttgatta aattataatc aaagctcttg
      721 ttggcacctt tcgatcccat tcgctgtctg cctccggaaa ctaaaaaaag caatatagat
      781 aatactcaag ataaatcaat tcacagcgtc taaaaaagca atcgttaatg tcatcacatt
      841 a
//
LOCUS       DAJVBX010000384          840 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.387, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000384 DAJVBX010000000
VERSION     DAJVBX010000384.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 840)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 840)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..840
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.387"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..>840
                     /locus_tag="OPV72_004495"
     CDS             <1..>840
                     /locus_tag="OPV72_004495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010835222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF4765 family protein"
                     /protein_id="HCR9916603.1"
                     /translation="SINDDVDTNKCEVKISLNYSYENIDGGRGCLSLPFDQNGYPIPP
                     DFHNCVNGITSKKMLLDLFLKHILHDHLNASGEVANVYANVIYKEIDPAAIAHTSSCF
                     SQVTMSGEHELFNVDSVTVPPKSTEQIIFEGKEIQKQIFLSSHSRNHLQPVTIHKMDR
                     SIKNIAVTGLLLSSRLAVTSGDYRIKNGNSEGENDFLPVKELQRYERALPEDHPAPTT
                     EPNLAGKVLDGLFEHVTSMAGGRYRKQASYPPLSSEAPNTIKYGDRELVLTKEPGSET
                     YQA"
BASE COUNT          282 a          155 c          172 g          231 t
ORIGIN      
        1 gcagtatcaa tgacgatgta gataccaata aatgcgaggt aaagatatct ctaaattaca
       61 gttacgaaaa tattgatggg gggcgaggat gtttatcgct tccatttgat caaaacggct
      121 atccaattcc ccctgacttt cacaactgtg taaatggaat cacatcaaaa aaaatgttgt
      181 tagatctatt tctaaaacat attttgcacg atcatttaaa tgcaagcggt gaagttgcaa
      241 acgtttacgc caatgttatt tataaagaga ttgatcccgc tgcaattgca catacatcgt
      301 cgtgtttttc tcaggtaacg atgagtggtg aacatgagct atttaatgta gatagcgtaa
      361 ctgttccacc taaaagcact gagcaaatta tatttgaggg aaaggaaatt caaaagcaaa
      421 ttttcttatc ttctcatagc cgcaatcatc ttcagccagt aaccattcat aaaatggaca
      481 ggagtattaa aaacattgca gtaactggtt tgttattatc atcaagatta gcagtaacat
      541 ctggtgatta taggataaaa aatggtaatt cagagggtga gaatgatttt ttacctgtta
      601 aagaattaca gagatatgaa agggctctcc cggaggatca tcctgcccca actacggagc
      661 ctaacctggc aggtaaggtg ttagatggcc tatttgaaca cgttacatct atggcagggg
      721 gacgctacag aaaacaagcc tcatatccac cgctgtcatc ggaagcgcct aatacgataa
      781 aatatggcga cagagagctc gttttaacta aagaacccgg ttcagaaacg tatcaggcaa
//
LOCUS       DAJVBX010000385          832 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.388, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000385 DAJVBX010000000
VERSION     DAJVBX010000385.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 832)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 832)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..832
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.388"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..>832)
                     /gene="rfbK"
                     /locus_tag="OPV72_004496"
     CDS             complement(<1..>832)
                     /gene="rfbK"
                     /locus_tag="OPV72_004496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="O-antigen biosynthesis phosphomannomutase RfbK"
                     /protein_id="HCR9916604.1"
                     /translation="GIYEHSSAGRDLYKPLFIALGAEVISLGRSDNFVPIDTEAVSKE
                     DREKARSWAKEFDLDAIFSTDGDGDRPLIADEAGQWLRGDILGLLCSLALGAEAVAIP
                     VSCNSIISSGRFFKHVKLTKIGSPYVIEAFNELSRSYSRIVGFEANGGFLLGSDICIN
                     EQNLHALPTRDAVLPAIMLLYKSRNISISALVNELPTRYTHSDRLQGITTDKSQSLIS
                     MGRENLSNLLSYIGLENEGAISTDMTDGMRITLRDGCIVHLRASGNAPELRCYAEANL
                     L"
BASE COUNT          263 a          193 c          144 g          232 t
ORIGIN      
        1 taataaatta gcttctgcat agcagcgtaa ctcaggtgca ttaccagagg cgcgcaaatg
       61 cacaatacat ccatcacgta aggtaattcg cataccatct gtcatatctg tagaaattgc
      121 accttcattc tccaaaccaa tatagcttaa gaggttgctc agattttctc tgcccatact
      181 aattaaggat tgacttttat cagtcgtaat tccctgtaat ctgtcagaat gggtgtaacg
      241 agttgggagt tcattgacta aagcgctaat gctgatattc ctacttttgt aaagtagcat
      301 tattgctggt aatacagcat cacgagttgg taaggcatga agattctgct cgttaataca
      361 gatatcgctt cctaataaaa aaccgccatt ggcttcaaaa ccgacaatac gactataact
      421 ccgagataat tcattaaaag cttcgataac ataaggcgag ccaattttcg taagtttaac
      481 atgtttaaaa aagcggccag aagaaattat gctattacaa ctaacaggaa tagcgaccgc
      541 ttctgccccc aatgcaagtg aacataatag acctaatata tcgcctctta accactgacc
      601 ggcctcatca gcaataagag gacgatcacc atccccatct gttgagaata tggcatctaa
      661 atcgaactct ttagcccatg agcgtgcttt ttcccgatcc tctttgctta cagcctctgt
      721 atctataggt acaaagttat cgcttctacc caagctaatg acttcagccc ccaatgcaat
      781 aaataaaggc ttataaagat cacgcccagc gcttgaatgt tcgtaaatac ca
//
LOCUS       DAJVBX010000386          818 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.389, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000386 DAJVBX010000000
VERSION     DAJVBX010000386.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..818
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.389"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..671)
                     /gene="sifB"
                     /locus_tag="OPV72_004497"
     CDS             complement(<1..671)
                     /gene="sifB"
                     /locus_tag="OPV72_004497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system effector SifB"
                     /protein_id="HCR9916605.1"
                     /translation="MPITIGRGFLKSEMFSQSAISQRSFFTSLWEKIKDFFCDTQRST
                     ADQYIKELCDVASPPDAQRLFDLFCALYELSSPSCRGNFHFQHYKDAECQYTNLCIKD
                     GEDIPLCIMIRQDHYYYEIMNRTVLCVDTQSAHLKRYSDINIKASTYVCEPLCCLFPE
                     RLQLSLSGGITFSVDLKNIEETLIAMAEKGNLCDWKEQERKAAISSRINLGIAQAGVT
                     AIDDA"
BASE COUNT          245 a          165 c          154 g          254 t
ORIGIN      
        1 atagcatcgt caatagctgt tacacctgct tgtgcgatgc ccagattaat cctggaggag
       61 atggcggctt ttctttcctg ttccttccag tcacataaat tccccttttc tgccatggcg
      121 ataagcgtct cttctatatt ttttaggtca acggaaaatg ttataccgcc ggatagcgag
      181 agttgtaacc gctcagggaa caagcaacat agcggttcac aaacataagt gctagctttt
      241 atattaatat cagaatatct tttcaggtgg gcagactgag tatcaacaca gagcactgtt
      301 ctattcatta tctcataata gtagtgatcc tgacgtatca taatacataa cggaatatct
      361 tcgccatctt taatacagag atttgtatac tgacactcag catctttata gtgctgaaaa
      421 tggaaatttc ctctgcatga tggtgatgat aattcatata acgcgcaaaa taaatcaaat
      481 aaacgttgcg cgtcaggcgg agaggcaaca tcacataatt cctttatata ttgatcggca
      541 gtggatcttt gcgtgtcaca aaaaaaatct ttaatctttt cccatagtga cgtaaagaag
      601 gagcgttgag agatagcact ttgagaaaac atctcactct ttaaaaatcc tctcccgata
      661 gtaattggca taatgtagac cacaagtgat tatatgatac ttcattactg gaataggtgg
      721 tattcgaaat attatcccat gttgcccatc ggtttgccta tcggtgaaac acctgatttt
      781 tgctttgtcc tgaaccgtca acattattgt taaaatcg
//
LOCUS       DAJVBX010000387          813 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.390, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000387 DAJVBX010000000
VERSION     DAJVBX010000387.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..813
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.390"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            3..>813
                     /gene="siiC"
                     /locus_tag="OPV72_004498"
     CDS             3..>813
                     /gene="siiC"
                     /locus_tag="OPV72_004498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000214858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-4 type I secretion system protein SiiC"
                     /protein_id="HCR9916606.1"
                     /translation="MTTYYNISKYREMIDGVNLEKEFYKKMLETFSLLVSSGVAMQSD
                     MRKVQVSIDALNTRSIMYQSMLDDEMYKMQNMTGLNLSPDQIQSDEKFNLFKKYIFVE
                     SPEKLMDMVMKYNDDYKMLVNTRKAATEDINAAKSSYFPTVDLVSSYVQNNPSGSAKK
                     SDYEDEFKTGINVSFNIFNGFRNAAQERKMVASYSQAKLQIDDFLIKTRYNIDSQLSK
                     YTAAKETYSVAERSHTNALQLTELYEQEFQLGQKSLLDLISSRNEAFQAYVS"
BASE COUNT          286 a          137 c          160 g          230 t
ORIGIN      
        1 ttgtgacaac ctattacaac atcagtaaat atcgtgaaat gattgatggc gtaaatctgg
       61 agaaagagtt ttataaaaag atgctggaaa ctttttcgct actggtatct tccggtgtag
      121 ctatgcaatc tgatatgcgt aaagtacaag tatctatcga tgcattaaat accagaagta
      181 ttatgtatca gtcgatgctg gatgatgaaa tgtataaaat gcagaatatg actggtctga
      241 atttatcacc agatcagatt caaagcgatg aaaaattcaa cctcttcaaa aaatatatct
      301 ttgtcgaaag ccctgaaaaa cttatggaca tggtgatgaa atacaacgat gactataaga
      361 tgcttgtcaa tacccgaaaa gctgcgaccg aagatattaa tgccgcaaaa tcatcctatt
      421 ttccgactgt agatctcgtt tccagctatg tacagaataa tccgagcggt agtgccaaaa
      481 aaagtgatta tgaagatgaa tttaaaacgg gtatcaatgt cagtttcaac atttttaatg
      541 ggtttagaaa tgcagcccag gaaagaaaaa tggtggcaag ttactcgcag gctaagctgc
      601 aaattgacga tttcttgatt aaaactcgtt ataacattga ttcacaactt tcaaaataca
      661 ccgctgcaaa agagacttac tcagtggcgg aacgttcaca tacaaacgcg ttacagctta
      721 ctgaattata tgagcaggag tttcagttag ggcaaaaaag tttgcttgat ttaatttcaa
      781 gccgtaatga agcatttcag gcatatgtaa gca
//
LOCUS       DAJVBX010000388          806 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.391, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000388 DAJVBX010000000
VERSION     DAJVBX010000388.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..806
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.391"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            399..>806
                     /locus_tag="OPV72_004499"
     CDS             399..>806
                     /locus_tag="OPV72_004499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HCR9916607.1"
                     /translation="MLSKKIGLSMIVLGIMSSSAFADSIVEGRTLNVAVSPASPPMLF
                     KSADGKLQGIDLELFSSYCQSRHCKLNITEYAWDGMLGAVASGQADVAFSGISITDKR
                     KKVIDFSEPYYINSFYLVSMANHKITLNNLNELN"
BASE COUNT          243 a          150 c          154 g          259 t
ORIGIN      
        1 agaaaatgta tttgacaagc aaagataagt ctttatattg gccctggata gagtggtaag
       61 atgatactta gagacattaa atacaccgtc actgaagcat ttatctgctt atcatgtaaa
      121 tatgtatgcg taaatggagc ataaactatg tccagtatac taatgtctat ggtatcttta
      181 cattttcacc tttcattggg tcgctgcact catatccagt tgatatctca tggtatattc
      241 aatccattcc ctttgatgat tcctgtcaaa cctcctgatt aaattagtta acagcgatgg
      301 aatacataac gttaagtact ttacgcctgc aaatgtcagg ttcacgctct aatgcttaat
      361 ttataatacg tattacctta ccacaggaaa tagatagcat gttatccaaa aaaattggct
      421 tatcgatgat agtgttggga ataatgtcgt cttcagcttt tgctgatagc atcgttgaag
      481 ggagaacact caatgtcgca gtatcaccgg cctctccccc tatgttattt aaaagtgctg
      541 atggcaaatt gcaggggata gatctggagc ttttttcgtc ttactgtcag tcacggcatt
      601 gtaagctaaa catcaccgaa tatgcctggg atggaatgct tggcgcagtg gcgagtggtc
      661 aggctgatgt agcattttcg ggaatttcaa tcacagataa acgtaagaaa gttattgatt
      721 tttctgaacc ttattacatc aactcttttt atctggtcag tatggccaat cataaaataa
      781 cgctcaataa cctcaatgaa ttaaat
//
LOCUS       DAJVBX010000389          803 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.392, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000389 DAJVBX010000000
VERSION     DAJVBX010000389.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 803)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 803)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..803
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.392"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..298
                     /locus_tag="OPV72_004500"
     CDS             <1..298
                     /locus_tag="OPV72_004500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="amino acid-binding protein"
                     /protein_id="HCR9916608.1"
                     /translation="LEPKGYYSLSKVKLYPTYNETMTDLKNGNLDLAFIEEPVYFTFK
                     NKKKMPIESRYVFKNVDQLGIAFKKGSPVRDDFNLWLKEQGPQKISGIVDNWMK"
     gene            305..>803
                     /locus_tag="OPV72_004501"
     CDS             305..>803
                     /locus_tag="OPV72_004501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460593.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HCR9916609.1"
                     /translation="MSSGNMLAIFYFLLEGIGNTLLVTFTCFLSAFLTGLTVAVLRRL
                     SPLPLQKILDVLVFILRGIPILIAVFLVYFGLPSIGIYVSPLVAMNLSVGLISGSYLA
                     EVFRGALKLVEPFEITVAKVAGMRQLQVIINIELPQMLRFSVPGIINEFSSVLKATPF
                     AYTVGI"
BASE COUNT          219 a          155 c          172 g          257 t
ORIGIN      
        1 tctggagccc aaaggatact actcgttaag taaagtaaaa ttatatccaa cctataacga
       61 gacgatgact gatctaaaaa atggtaatct tgatctggct tttatagaag agccggttta
      121 ctttaccttc aaaaataaga aaaaaatgcc gatagaaagt cgttatgttt tcaagaatgt
      181 tgatcagctt ggcattgcct ttaagaaagg ctctcccgtg cgcgatgatt ttaacttatg
      241 gcttaaagag caagggccac aaaaaatatc tggcatcgtt gataactgga tgaaatagta
      301 agctatgtca tcaggtaata tgctggctat cttttatttc ctattggaag ggattggtaa
      361 tacgctgctt gtaaccttta cctgttttct ctcagcgttt ttgaccgggc ttacagtcgc
      421 cgtattacgg cgactatccc cccttccact acagaagata ctcgacgtac tggtctttat
      481 tcttcgggga attccaatac ttattgctgt ttttcttgtt tattttggat tgccatcgat
      541 tggcatatat gtttcacctc tggtggccat gaacctcagc gtcggcttaa tcagcgggag
      601 ttatcttgcc gaggtgttca gaggggcgct taaattagtt gagccattcg aaataacggt
      661 agcgaaagta gcaggaatgc gtcaattaca ggttataata aatattgaac tgccacagat
      721 gttgcgattt tctgtgcccg gtattatcaa tgagttttct tctgtattaa aagcgacgcc
      781 ctttgcttat actgtaggca tcg
//
LOCUS       DAJVBX010000390          800 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.393, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000390 DAJVBX010000000
VERSION     DAJVBX010000390.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 800)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 800)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..800
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.393"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..390)
                     /locus_tag="OPV72_004502"
     CDS             complement(<1..390)
                     /locus_tag="OPV72_004502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000871135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916610.1"
                     /translation="MKWIIMVLVFSFSNVYAEDCSQQDFDKADMALDSLASWKAVDGF
                     YSRHSQCDVGYLREGTSEKIIRLLVDRWGELNELSALIKRKPALGDYVIDHIGEILDV
                     KDVEKIRDYSASHCQIDSKDLCKKLHDA"
     gene            complement(506..>800)
                     /locus_tag="OPV72_004503"
     CDS             complement(506..>800)
                     /locus_tag="OPV72_004503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010989205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916611.1"
                     /translation="TDAATNKNSFFTKNDDGEWEAVTDGVPVLADVNITPKFIGMSAI
                     VSCRYKDDAGYHIDQCFQAVIVLSTNIMFVFIGRGDSSLFNNYKEIYRSFKVK"
BASE COUNT          259 a          182 c          107 g          252 t
ORIGIN      
        1 tgcatcgtgc agttttttac atagatcttt actatcaatt tggcaatgag atgctgaata
       61 atcccttatt ttttcaacat cttttacatc gagtatctct ccaatatgat caataacata
      121 atcgccaagt gctggtttcc ttttgataag cgcagataac tcattcaatt ctccccatct
      181 atccactaac aatctgataa ttttttctga cgtgccttcc cggaggtagc ccacatcaca
      241 ttgactatgt cgggaataaa agccatcgac agctttccat gacgcaagag agtctaacgc
      301 catatccgct ttatcaaagt cttgttgtga acagtcttca gcataaacat tagaaaaaga
      361 aaaaactaaa accataatta tccacttcat ctaaagtata ttctcatcga ttgattaatt
      421 ccatatccag tctgctcatt atgaagcatc acacagtcgt aattaatgaa aaacattcac
      481 ccaatcccca tcaattaatc acatgctatt taaccttgaa tgagcgatat atttccttat
      541 aattattaaa taaggatgaa tcgcctctac caataaaaac aaacattatg tttgttgaca
      601 atactatcac tgcctgaaag cactggtcta tatgataccc agcatcatct ttgtacctac
      661 atgaaacgat tgcactcatg ccaataaatt ttggcgtaat atttacatca gctaaaacag
      721 ggacgccatc agtaacggcc tcccattctc catcatcatt ctttgtaaaa aaagaatttt
      781 tattcgttgc cgcatctgtg
//
LOCUS       DAJVBX010000391          791 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.394, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000391 DAJVBX010000000
VERSION     DAJVBX010000391.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..791
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.394"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            382..>791
                     /locus_tag="OPV72_004504"
     CDS             382..>791
                     /locus_tag="OPV72_004504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3626 domain-containing protein"
                     /protein_id="HCR9916612.1"
                     /translation="MLKPIFYSGSVKVPECLETDKEKNVGRTPLSSDIQQIKNVVEDI
                     PPFPESRAVGGSVSAAYRLSFDEVFCGLSNEERKKVYGRLFGKQVLAHIHSRCQRDAD
                     IIREKALRRISRECGTEIDCALLLNKMVDILQNAR"
BASE COUNT          237 a          134 c          180 g          240 t
ORIGIN      
        1 ggttatcaaa ataatttatc aaaacgtcct caattcagac cgcaatagta gtccatcctt
       61 taccccgatc gtcatgataa cctgagaccc cctgaaagct gatagttacc gattttgatt
      121 gtggtggttt tctttatgat gtgtggtttg gctatttttt gaaagtgcct taccagattt
      181 attgttatta tcaggggatt atttcaataa aaggtgatga tttattgcct gcaatagtgg
      241 gtagattaag cattttatga aattattagt gtctttattt gcacttctac aagactgtta
      301 agaggtgttg aaatatcagc ctggtaaaga atacgtcagc gaaagtgaat gctatattag
      361 tcataaaaat tcaggagaca tatgctcaaa cctatcttct acagtggaag tgtgaaggtt
      421 ccggaatgtc tggaaacaga taaggaaaaa aatgtcggac gtactcctct gtcttcagac
      481 attcagcaaa ttaaaaatgt tgttgaagat attccgccat ttccagaaag cagagcggtg
      541 ggaggttctg taagcgcagc gtacaggctt tcttttgacg aagtgttttg cggtctcagc
      601 aatgaagagc gtaaaaaggt gtatggtcgc ctttttggaa aacaagtact tgcgcatatt
      661 cattccaggt gtcagcgcga cgctgacata ataagagaaa aagcgctcag gcggataagc
      721 cgtgagtgtg gtaccgaaat agattgcgct ctcttactaa ataagatggt ggatatttta
      781 caaaatgccc g
//
LOCUS       DAJVBX010000392          787 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.395, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000392 DAJVBX010000000
VERSION     DAJVBX010000392.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..787
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.395"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..>787
                     /locus_tag="OPV72_004505"
     CDS             <1..>787
                     /locus_tag="OPV72_004505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HCR9916613.1"
                     /translation="LKNHESLLAGTAVSSAFATQKLAQGSSVAAFLKSHESLFASTAV
                     SSAFAAQKLVQDSGITALFKKQGGIFNENYFATSIAKQLEKLDATEIQTLQEAAILFS
                     RSPQGAAIIATNIHAVEVKEPDALTKLKNYIEKSPITSNFRKLPLLVQLIIIYLVTTM
                     YSVVVDKNKELAMNLMEQAQQYVSKSISPRTHFKELTKQLPREVDISTLKHIRIITGE
                     NVRLRNTPSMQGDVLVKLEKYTPVIVIDKSDRKWLYVQLSFGEQ"
BASE COUNT          286 a          164 c          141 g          196 t
ORIGIN      
        1 ctgaaaaacc atgaatcact tcttgccggt accgctgtca gcagcgcatt cgcaactcag
       61 aagctggcac agggctccag cgttgccgct ttcctgaaaa gccatgaatc actttttgcc
      121 agtaccgctg tcagcagcgc attcgcagct cagaagctgg tgcaggactc gggcattacc
      181 gctcttttca aaaagcaggg ggggatattc aacgaaaatt atttcgctac aagcattgct
      241 aaacaattag aaaaattaga tgcaaccgaa attcaaacat tacaggaagc ggccattcta
      301 ttttcacgct cacctcaagg tgcagcaatt attgcaacaa atatccatgc agtagaagta
      361 aaagagcctg acgcattaac aaaattaaaa aattatatcg aaaaaagccc tataacttca
      421 aactttagaa aattaccatt attagtacaa ctcatcatca tttatcttgt aaccaccatg
      481 tattcagtcg ttgtggataa aaacaaagaa ttagcaatga atttaatgga acaagcgcaa
      541 caatatgtta gtaaatctat atcaccaaga actcatttta aagaattaac aaaacagtta
      601 ccccgcgaag ttgacattag cacattaaaa cacataagaa taattactgg agaaaatgtc
      661 cgattacgga acacaccatc aatgcaaggc gatgtattgg ttaagttgga aaaatatact
      721 cccgtgatcg ttatcgataa aagtgacagg aaatggttat atgtacaact gtcattcgga
      781 gaacaaa
//
LOCUS       DAJVBX010000393          779 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.396, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000393 DAJVBX010000000
VERSION     DAJVBX010000393.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 779)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 779)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..779
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.396"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..95
                     /locus_tag="OPV72_004506"
     CDS             <1..95
                     /locus_tag="OPV72_004506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR9916614.1"
                     /translation="WFYTIITSIIMLMVSTLVLTKYRSRIVYWL"
     gene            99..>779
                     /locus_tag="OPV72_004507"
     CDS             99..>779
                     /locus_tag="OPV72_004507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR9916615.1"
                     /translation="MKISCKNVGVILPIFNSSHRSFKKTFLQAASGGRIGSSNTGIIE
                     VEALKKIDFTLTEGNRLALIGHNGSGKTTLLRVLAGAYKPTSGKYECIGRVTSLIDPM
                     MGMDGELTGLENIKLRGLFLGLSKNEIKNITEDVIEFSELGDFIKIPVRTYSSGMVLR
                     LGFSISTAINPEILLMDEWMSVGDSDFKRKAEMRLNSFISKAGIMVMATHDDELAKSV
                     CNKFIRLEH"
BASE COUNT          243 a          130 c          167 g          239 t
ORIGIN      
        1 tatggtttta cacaataata acctctatta ttatgttgat ggtctcaacc ttagtgttga
       61 ctaaatatcg ctcaagaatc gtatactggt tataattaat gaaaatctct tgcaaaaacg
      121 ttggcgtaat actccctata tttaactcca gccaccgttc atttaaaaaa acttttttac
      181 aggctgcttc aggtggacga attggctcat cgaataccgg gattattgaa gtagaggcat
      241 taaaaaaaat tgattttacg cttaccgaag gtaaccgtct tgcgcttatc ggacacaatg
      301 gttcgggcaa aacaactctt ctgagagtac ttgcaggggc ctataaacca acttcaggga
      361 agtatgaatg tattggtcga gtcaccagcc tcattgatcc catgatggga atggatggtg
      421 agcttaccgg cctggaaaat ataaaactga ggggactatt tctcggtctg tcaaaaaatg
      481 aaataaaaaa tattacagaa gatgtcatcg agttcagcga gttaggtgat tttattaaaa
      541 tccccgttag aacgtattct agtggtatgg ttctgaggct tggtttttct atttctactg
      601 caattaatcc tgaaatttta ctgatggatg aatggatgag cgtgggtgat agtgatttta
      661 aaagaaaagc agagatgaga ttaaatagct ttatctctaa agcgggcatt atggtaatgg
      721 ccactcatga tgatgaactg gctaaatctg tatgtaataa gttcatcagg cttgagcac
//
LOCUS       DAJVBX010000394          761 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.397, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000394 DAJVBX010000000
VERSION     DAJVBX010000394.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..761
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.397"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..713)
                     /locus_tag="OPV72_004508"
     CDS             complement(<1..713)
                     /locus_tag="OPV72_004508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001681522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HCR9916616.1"
                     /translation="MDAPEDVSKYQLQDRDIVISRAGSVGFSFLVQNPPSQVVFASYL
                     IRFKPVNYFSEYYLKRFLESSDYWNQLSLMSAGNAVQNVNAQKLSTLTVPIPPIAEQK
                     IIAEKLDTLLAQVDSTKARLEQIPQILKRFRQAVLAAAVSGLLIGSNKRNHHPLCSEW
                     QWPDLPSTWSVHKYSELVDSRLGKMLDKAKNFGSATKYLGNINVRWFSFDLENLQDIL
                     ISDIERRELSLKLGDVLIC"
BASE COUNT          224 a          151 c          143 g          243 t
ORIGIN      
        1 tcacatatta aaacatcgcc aagcttgagt gataattctc tgcgctctat atctgaaatt
       61 agtatatctt gaaggttttc taaatcaaaa ctaaaccagc gaacatttat atttccaaga
      121 tattttgttg cagagccaaa atttttagct ttatcaagca ttttacctag tctgctatca
      181 acaagttcag agtatttatg aacactccaa gttgatggta ggtctggcca ttgccattca
      241 ctacataatg gatggtggtt tcttttattt gaaccaatta acaacccgct taccgcagca
      301 gctagcaccg cctgacgaaa acgtttcagg atttgtggga tttgctcaag acgtgctttg
      361 gtgctgtcta cctgtgccag cagcgtatcg agtttttcgg cgatgatttt ttgttcggct
      421 ataggtggta ttggtactgt aagtgttgat aacttttgag cattaacatt ttgtacagca
      481 ttccctgctg acattaaaga cagctgattc caatagtcac tcgactctaa aaaacgtttt
      541 aagtaatatt ctgaaaaata attaactggt ttaaatcgaa taaggtatga agcaaaaaca
      601 acttggcttg gagggttttg taccaaaaaa ctaaacccaa ccgaaccggc tcgagatatc
      661 acaatatctc tgtcctgtaa ttggtatttt gaaacatctt ccggggcatc catgcaataa
      721 ggtacactgg accagtcaac cgctcctttt gtaatatcgg t
//
LOCUS       DAJVBX010000395          742 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.398, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000395 DAJVBX010000000
VERSION     DAJVBX010000395.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..742
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.398"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            82..>742
                     /locus_tag="OPV72_004509"
     CDS             82..>742
                     /locus_tag="OPV72_004509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR9916617.1"
                     /translation="MKQLNGGNVYRPTGKEKNLQAILNIHRHVIQNISPVTITAGKTL
                     DIKIDNQSHILLITKGAIKVCRRIDSIVMGCGVSPMILGLVDAYADLYQLEENSDVFF
                     IAETTCEYYPVPVKDFVEIADEKHLWRDISNILMYRIAFMSNRDRNLIGQDAYSQIKA
                     LLLELWSYPESSRFEINAQNFIQQRTGLSRSRIMQVLSELKAGNYIKILHGRLLELRN
                     LP"
BASE COUNT          232 a          155 c          153 g          202 t
ORIGIN      
        1 aattataatt taagtgaata ttaaatttat gtttaccttt taatagtcaa ccactttatc
       61 agccataata atggggaaga tatgaagcag ttaaacggcg ggaatgtgta tcgtcccaca
      121 gggaaagaaa aaaacctgca agccatttta aatattcatc ggcacgttat tcaaaacatc
      181 tcccctgtca ctattacggc cggtaaaacc ctggatatca agattgataa tcaatcccac
      241 atcctgttaa tcactaaagg cgctattaaa gtatgtcggc gtatcgacag tattgtaatg
      301 ggctgtggtg tctcgccaat gattttaggc cttgtagatg cctatgccga cttataccag
      361 ttagaagaga attcagacgt cttttttatc gccgaaacca cctgtgaata ttatcctgtc
      421 ccagtaaaag attttgtgga aatagccgat gaaaagcatc tctggcgtga catttcgaac
      481 atcctgatgt accgcattgc tttcatgagt aaccgtgaca gaaaccttat cgggcaggac
      541 gcctatagcc agataaaagc gctgttactt gaactgtggt cgtatcctga aagctcacga
      601 tttgagatca acgcacagaa cttcatacag cagagaaccg ggctttcacg cagccgtatc
      661 atgcaggtac tttcagaatt aaaagcgggg aactatataa aaatactgca tggaagactg
      721 ttagagcttc gaaacctgcc gg
//
LOCUS       DAJVBX010000396          737 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.399, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000396 DAJVBX010000000
VERSION     DAJVBX010000396.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..737
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.399"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            63..>737
                     /locus_tag="OPV72_004510"
     CDS             63..>737
                     /locus_tag="OPV72_004510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCR9916618.1"
                     /translation="MRPIKNAKKIDYNLIKVFDTVITEGNATRAARKLDVTPAAISQA
                     LLRLQNLYGEELFIRTRKGLVPSSKGKSLHQVFRQAIESIESTLCDKTDAQESNELIV
                     LGSDITENYYFPALLDTVLMNRYIIKHYAIKKTGEYSPASMLTHGYADIIMGILEIKN
                     EMIESFLIDNLSDFVCVCGEKSPLVGLEKMSLYNFYAARHAVYHSDMFSSFNADSIDL
                     FKSSTPY"
BASE COUNT          225 a          132 c          158 g          222 t
ORIGIN      
        1 ggtgcaaggt taatctgcgc cttaaatgat ggtgccagat tataccagcc aggataacct
       61 atatgcggcc aataaaaaat gctaaaaaaa ttgactacaa tctgatcaaa gtgttcgata
      121 cggttattac tgaaggaaat gcaaccaggg ctgcgaggaa actggatgtc acgcctgcgg
      181 cgatctctca ggctcttctt cgtttacaaa atctttatgg cgaagagtta tttatcagaa
      241 cccgcaaagg attagtcccg tccagcaaag gtaaatcgct tcaccaggta tttcgccagg
      301 caattgaatc tatagaaagc acactgtgcg ataaaacaga tgcgcaggag agtaatgaac
      361 tcattgttct gggaagtgat atcactgaaa attactattt tccggcattg ctggatactg
      421 tgttgatgaa tcgatatatt attaaacact atgcgattaa aaaaacaggg gaatactcgc
      481 cagcctccat gctgacgcat ggctatgcgg atatcatcat gggaattctg gaaattaaga
      541 atgagatgat cgaaagtttt cttattgata atttatctga ttttgtttgt gtttgtggtg
      601 aaaaaagtcc attggttggg cttgaaaaaa tgtctttata taatttttat gctgccagac
      661 atgctgtcta tcattcagat atgttctctt ctttcaatgc tgatagcatt gatttattca
      721 agagcagtac gccttat
//
LOCUS       DAJVBX010000397          726 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.400, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000397 DAJVBX010000000
VERSION     DAJVBX010000397.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..726
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.400"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..100
                     /locus_tag="OPV72_004511"
     CDS             <1..100
                     /locus_tag="OPV72_004511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001515480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="AlpA family phage regulatory protein"
                     /protein_id="HCR9916619.1"
                     /translation="KQVKTGLRSIAFIESEIDEWIYKIISDSRNHI"
     gene            130..441
                     /locus_tag="OPV72_004512"
     CDS             130..441
                     /locus_tag="OPV72_004512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001515481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916620.1"
                     /translation="MKSKNVLPCVVTVTNDETEVFMEMAINNFRKHLQVMIDCMGNDY
                     ERHFKDRLYIEEVIGKVIERTKREFAESMKDNKGKEYHLFLDEVRRNLRVIYSAYRTN
                     Y"
     gene            456..>726
                     /locus_tag="OPV72_004513"
     CDS             456..>726
                     /locus_tag="OPV72_004513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001515482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916621.1"
                     /translation="MNEKCLGWNEIPVKISASNAETANFATDVVNTYNELIHYLYFNL
                     SDDEFLKKMKDGFYREIFIMDIINLTLQEWFESAEEIKIKYISVPE"
BASE COUNT          273 a           83 c          156 g          214 t
ORIGIN      
        1 taagcaagta aaaaccggat tgcgctctat agcatttatt gaaagtgaga ttgatgaatg
       61 gatttacaaa atcatttctg attctcgcaa tcatatctaa aaaagtttat taaataatga
      121 gaggttaaga tgaaaagtaa aaacgtactg ccttgtgtgg tgactgttac gaatgatgag
      181 acagaagtat ttatggaaat ggcaataaat aactttagaa aacatcttca ggtcatgatt
      241 gattgtatgg gaaatgatta cgagcgtcat tttaaagacc ggctttatat tgaagaagtg
      301 attggaaaag tgatcgagcg aacaaaacga gagtttgctg aatcaatgaa agataataaa
      361 gggaaagaat atcatctgtt cttggatgag gtgagaagga atctgagagt tatttattct
      421 gcgtatcgta ctaactatta atgagagagg tgaatatgaa cgaaaaatgt ttaggctgga
      481 atgaaatacc cgttaaaata tccgcaagta atgctgagac agcaaacttt gctactgatg
      541 ttgtaaatac ctataacgag ttaatacatt acttatactt taatctaagt gatgatgaat
      601 ttctgaaaaa aatgaaggat ggattttaca gggagatatt cataatggat attattaatc
      661 tcacgctaca ggaatggttt gaaagtgctg aagagataaa gattaaatac atatcagttc
      721 cagagg
//
LOCUS       DAJVBX010000398          724 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.401, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000398 DAJVBX010000000
VERSION     DAJVBX010000398.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 724)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 724)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..724
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.401"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
BASE COUNT          214 a          157 c          140 g          213 t
ORIGIN      
        1 accatgaaat ataatgaagg cacgtttaaa tatatgctca aaaaaatcat tggcgctctc
       61 gcgtcaatta ttggcgggct acttgctttt ttatgtgtct attggttatt tcgtctggat
      121 acctggacag aacgaggggt ttatataggc atctctatat ttttggctct tattctcata
      181 aaaatactat catttttcaa tgatgaatag acggcaggaa aaaccgtgag tgtctcacac
      241 cgattcttgc tggatgtcaa atttcgaaag cctgccctgc tgatacccta tcaagaagaa
      301 actaacccaa caattatcag acagtagcag gaatcgaacc cacaccaggc aaatcacgta
      361 gataattctg taagggttag ttttgtggtg gtcttgataa acggtaaaaa atagctttaa
      421 cagtccatta gcccaaagga cttctccgag tccgggctcc aaccattcag atgcggacgc
      481 cctatggcgt ccgtttttat ttataaaatc aacaggttac cccgcccttc atgttcacta
      541 ctgttcatta aaatatactg gcagccaccg ctttttgtgg gtaaaaacgc cggttttctg
      601 catagcgcat gacgctattg aaacgttatt tagcaaatcc tgtctgagcc agaaattaag
      661 tctctgttaa cctgcgctat tacagaaaat catagaacag tcgtctcaaa agaatatcgt
      721 cctg
//
LOCUS       DAJVBX010000399          720 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.402, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000399 DAJVBX010000000
VERSION     DAJVBX010000399.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..720
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.402"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            422..607
                     /locus_tag="OPV72_004514"
     CDS             422..607
                     /locus_tag="OPV72_004514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001729072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3289 family protein"
                     /protein_id="HCR9916622.1"
                     /translation="MQDHFSLDSNDITHWLYSHWDVFKIWFVLQHYEKEGYEFKPFIH
                     KIILDALRRQGKKSPGA"
BASE COUNT          250 a          119 c          155 g          196 t
ORIGIN      
        1 aataaataaa aaaaatgaag agatcgagat ttttactatt ccagtagttg gtgctaatta
       61 ctcatataaa gataaatttt tagtaaacgt ccatgatttt gaattatttg atggaaagat
      121 ctgtaacgct ttgatgccta tagatagtta tttttcacca taagaagggt tgttgaataa
      181 atcaaattac cctgtaccgt caaatgtacc taccgtcgac acgggtaacg gatctacatc
      241 ttctgggaag caaaaggcaa caacaaaaga tgcggaacaa ttgccgacag agggaaataa
      301 aatcgtggag ggcctatagc tacgggctga gattatctgt tcatgatatg tatggcacac
      361 acgttaccat aacatcattg aatgtatcaa aaatgcctac gcagcaaacg ggcattacag
      421 gatgcaggat cattttagtc ttgacagtaa tgatataaca cattggcttt atagccattg
      481 ggatgtcttt aaaatttggt ttgtacttca acattatgag aaagaggggt atgagtttaa
      541 gccatttata cacaaaatca ttctagatgc attgcggcgg caagggaaga aatccccggg
      601 agcatagata actctgtgac cggggtttct gagcgcagcc aacaaagagg cagcttaaag
      661 gatgaagtgt atattacaga aataaatacc accgtaaaaa tctcaggtgt cagaggatat
//
LOCUS       DAJVBX010000400          701 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.403, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000400 DAJVBX010000000
VERSION     DAJVBX010000400.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 701)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 701)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..701
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.403"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..401)
                     /locus_tag="OPV72_004515"
     CDS             complement(<1..401)
                     /locus_tag="OPV72_004515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCR9916623.1"
                     /translation="MMRKPSQIVHCISCDLSCQLFPDSAVRVQYCHNAAFSIWPDGNA
                     FLKKGFIEKLLLDRHNHLSSGFIFVDFSFPNLRRFTDLQWADSLANSGMHIVLISDRS
                     LTPLANYWILKSNKIQGIIYSDDDDIVQQQK"
BASE COUNT          236 a          137 c          120 g          208 t
ORIGIN      
        1 atcttttgct gttgcacaat atcatcgtca tcggaataaa taattccttg tattttattg
       61 cttttcaaaa tccagtaatt ggccagcgga gttaaacttc tgtcagaaat caggacaata
      121 tgcataccac tgtttgccag actgtcagcc cattgtaaat cggtaaatcg tcgaagattc
      181 gggaaagaaa aatcaacaaa gataaaaccg ctggataaat ggttgtgtct atcaagcaat
      241 aacttttcaa taaacccttt tttcaggaaa gcattaccat ctggccagat ggaaaatgcc
      301 gcattatgac agtattgcac ccgtactgcg ctgtcaggga ataattgaca ggataaatcg
      361 caactaatgc aatggacaat ttgtgaaggc tttctcatca tcctgaacga ctcccgtcga
      421 tgtttctatt aatatttcat tggtaaataa atgtgtcaat ccagataata tacagtgcta
      481 cggctgtcaa aagtcgcgaa ttattgtcag tgtcataaac tcctggaaag acctaaaata
      541 cagctttaag gaaccatgac agatccgaca gtcgtaatac atcatttcgg attcgtattt
      601 cacccattga gatttttata cataatctcc aatatcataa aaaatcttaa aacagcacta
      661 tttgctaaat tatgaggatg ataaataacg gttctcaata c
//
LOCUS       DAJVBX010000401          701 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.404, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000401 DAJVBX010000000
VERSION     DAJVBX010000401.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 701)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 701)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..701
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.404"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..>701
                     /locus_tag="OPV72_004516"
     CDS             <1..>701
                     /locus_tag="OPV72_004516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016505863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="fimbria/pilus outer membrane usher protein"
                     /protein_id="HCR9916624.1"
                     /translation="ELYFKSMTQTLEPCLTKEKLIKYGIAIQELHGLQFDNEQCVLLE
                     HSPLKYTYNAANQSLLLNAPSKILSPIDSEIADENIWDDGINAFLLNYRANYLHSKVG
                     GEDSYFGQIQLGFNFGPWRLRNLSSWQNLSSEKKFESAYIYAERGLKKIKSKLTVGDK
                     YTSADLFDSVPFRGFSLNKDESMIPFSQRTYYPTIRGIAKTNATVEVRQNGYLIYSTS
                     VPPGQFEIGREQIAD"
BASE COUNT          241 a          120 c          130 g          210 t
ORIGIN      
        1 ctgagttgta tttcaaatca atgactcaga ctctagaacc atgcttaaca aaagaaaaac
       61 ttataaagta tgggatcgcc atccaggagc ttcatgggtt gcagtttgat aatgaacaat
      121 gcgttctctt agagcattct cctcttaaat atacttataa cgcggctaac caaagtttgc
      181 ttttaaatgc accatctaaa attctatctc caatagacag tgaaattgct gatgaaaata
      241 tctgggatga tggcattaac gcttttcttt taaattacag agctaattat ttgcattcta
      301 aggttggagg agaagattca tactttggtc aaattcaact tggttttaat tttggtccct
      361 ggcggctaag gaatctatca tcttggcaaa acttgtcaag cgaaaaaaaa tttgaatcag
      421 catatattta tgctgagcga ggtttaaaaa aaataaagag caaactaaca gttggggaca
      481 aatataccag tgcagattta ttcgatagcg taccatttag aggcttttct ttaaataaag
      541 atgaaagtat gatacctttc tcacagagaa catattatcc aacaatacgt ggtattgcga
      601 aaaccaatgc gactgtagaa gtaagacaaa atggatactt gatatattct acttcagtcc
      661 cccccgggca attcgagata ggtagagaac aaattgctga t
//
LOCUS       DAJVBX010000402          701 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.405, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000402 DAJVBX010000000
VERSION     DAJVBX010000402.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 701)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 701)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..701
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.405"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            45..>701
                     /locus_tag="OPV72_004517"
     CDS             45..>701
                     /locus_tag="OPV72_004517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCR9916625.1"
                     /translation="MGRKWANIVAKKTAKDGATSKVYAKFGVEIYAAAKQGEPDPESN
                     SALKFVIERAKQAQVPKHVIDKAIDKAKGGGDETFVQGRYEGFGPNGSMVIAETLTSN
                     VNRTIANIRTIFNKKGGNIGAAGAVSYMFDNTGVIVFKGTDPDHIFEILLDAEVDVRD
                     VTEEEGNIVIYTEATDLHKGIAALKAAGITEFSTTELEMIAQSDVELSPEDLEIFEGL
                     V"
BASE COUNT          235 a          116 c          158 g          192 t
ORIGIN      
        1 taacctgcca ttaatgtaaa taattctttg aggagatgtt tccagtggga cgtaaatggg
       61 caaatattgt tgctaaaaaa acggctaaag acggtgcaac gtctaaagta tatgcaaaat
      121 ttggtgtaga aatctatgct gcggctaaac aaggtgaacc agacccggaa tcaaactcag
      181 ctttaaaatt cgttattgaa cgtgcgaaac aagcacaggt tccaaaacat gttattgata
      241 aagccattga taaagccaaa ggtggcggag atgaaacgtt cgtgcaaggg cgttatgaag
      301 gctttggacc caatggttca atggttatcg ctgaaacgtt gacgtctaat gttaaccgta
      361 cgattgctaa tatccgcaca atttttaata aaaaaggcgg gaatatcgga gctgcaggtg
      421 ctgtcagcta tatgtttgac aatactggag tgattgtatt taaaggaaca gaccctgacc
      481 atatttttga aattttgctt gatgctgaag ttgatgttcg tgatgtaacc gaagaagaag
      541 gaaacatcgt tatttatact gaagctacag acctgcacaa aggaattgca gcgctaaaag
      601 ccgctggaat tactgaattt tcaacaacag aattagaaat gattgctcaa tcagacgttg
      661 aactttcacc agaagattta gaaatctttg aaggacttgt t
//
LOCUS       DAJVBX010000403          688 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.406, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000403 DAJVBX010000000
VERSION     DAJVBX010000403.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..688
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.406"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(5..501)
                     /gene="sefA"
                     /locus_tag="OPV72_004518"
                     /pseudo
     CDS             complement(5..501)
                     /gene="sefA"
                     /locus_tag="OPV72_004518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001674837.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SEF14 fimbria major subunit SefA"
BASE COUNT          204 a          166 c          134 g          184 t
ORIGIN      
        1 taaattagtt ttgatactgc tgaacgtaga aggtcgcagt gaaagtacct gctggcaggg
       61 tcgatttacc aaaggttgtg acagggacat ttagcgtttc ttgagagctg gcaactcgcc
      121 aacctgcaag cccgtcaatt ccagtatttg cttggtcatt aatattggct ccctgaatat
      181 acccacggaa aacaggctgt ccttgtccat caacgaacgg gacagtggct acaccaccag
      241 ataccgaagc cccttacctg caatagatac tgagttatgt ggaccagtag cagtaatgct
      301 gagagtacca actttctgac cagcagcaac atcaggccct gtaaagccag gatcctgact
      361 ccagttggct gatgttgtat tctgagctgc aatagtaacc gctgcctgaa cctctgcttt
      421 gttaccaaca aagccagctg cgtgggcact gccacatgca attaaagcaa gaactgctac
      481 tgcagatgct gatttacgca tattacaaaa tctccaaaaa tcaactatta gcattcgcac
      541 aatttatctg tgcggatgct aatatactca cgccatttta aaaatttaag caaaaaacaa
      601 ggatcactat tttttatctt tacacgcccc ccccattaat aagcgaatga tccattaata
      661 ctttttgtgg aatatctaat atccacat
//
LOCUS       DAJVBX010000404          687 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.407, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000404 DAJVBX010000000
VERSION     DAJVBX010000404.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 687)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 687)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..687
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.407"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..>687)
                     /gene="pilV"
                     /locus_tag="OPV72_004519"
     CDS             complement(<1..>687)
                     /gene="pilV"
                     /locus_tag="OPV72_004519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shufflon system plasmid conjugative transfer
                     pilus tip adhesin PilV"
                     /protein_id="HCR9916626.1"
                     /translation="RDGTLPMTGDLNLDGHNINNIANINATGNITTTSDLQARNIKAT
                     GKVDADGDISSGRYLIAKSKDEDASIKIGGDGTGNHNFMFESQKRTSVVFFPSVNSAL
                     LTYKFRGNINILSPSGDSVGVKLNGTTGNITASGNIEAAQNVKGATLESTGRATVGEF
                     VQLNGQAEVGKVCQSNGLQGRTAKGKILSCVNGVWTGSVQINNSQCKWFSPANAFSYF
                     GEYSGQLHEKP"
BASE COUNT          193 a          151 c          111 g          232 t
ORIGIN      
        1 aggtttttca tgaagttgcc cactgtattc tccaaagtat gaaaaagcat tagccgggga
       61 aaaccattta cattgactat tatttatttg aaccgatccg gtccatacac cattaacaca
      121 agataaaatt ttcccttttg ctgttcttcc ttgtaatcca ttagattgac acacttttcc
      181 aacctcagcc tgtccgttca attgaacaaa ctcacccacc gtagcgcgtc cagtggattc
      241 taatgtagcg cctttgacat tttgggcggc ctctatgttt ccagaggcag tgatatttcc
      301 agtggtgcca tttaatttaa caccaactga atccccagaa ggacttaata tgtttatatt
      361 cccacgaaat ttataagtta acaatgcaga attaacgctt ggaaaaaaaa caacagatgt
      421 tcttttttga gattcaaaca taaaattatg atttccagtg ccatcgcctc caatttttat
      481 tgatgcatct tcatctttgc ttttagcaat caaatatctt cctgatgaaa tatcaccgtc
      541 agcatcaact tttcctgtag ctttaatatt tcttgcctgt aggtcgcttg tcgtcgtaat
      601 atttcctgta gcattgatat tagcgatatt gttaatatta tgtccgtcaa gatttagatc
      661 gccagtcatg ggcaaggttc catcccg
//
LOCUS       DAJVBX010000405          675 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.408, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000405 DAJVBX010000000
VERSION     DAJVBX010000405.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..675
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.408"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(344..613)
                     /locus_tag="OPV72_004520"
     CDS             complement(344..613)
                     /locus_tag="OPV72_004520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001766201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein NinG"
                     /protein_id="HCR9916627.1"
                     /translation="MAKLPRRKCKVCREWFPPAYSNVVWCCPEHGAIYALELRAKEKS
                     KAAARCIRGKHQADKAERQANGCMLRERQAVLYTLSRKMFRKHLR"
BASE COUNT          184 a          187 c          128 g          176 t
ORIGIN      
        1 tcgagtcaac acgatataca aaatcaacgg cacctgaatg accaaaaaaa tactaaaaat
       61 aatattactt ttttatcata ctctctccta cagaaactat caggcaaacc acctaatgtg
      121 ttaaaccgag tgctaaccat agctcagtca tactttacgt ctcgctggat aaaattagaa
      181 aaacaaacct ccccggttta cgggcacgaa aatcccggta attgcgcaat gccgatcctt
      241 aaactgcggc actataacgg cttcccctac agggagccgt tttgttatgt cacttctcaa
      301 tgacctgctc gatttcagcg accatcccct tatgccaccg ccttcagcgc agatgtttgc
      361 ggaacatctt cctgctgagt gtatacaaca ctgcctgacg ctctctaagc atgcaaccgt
      421 tcgcctggcg ttcggcttta tccgcctggt gtttacctct gatacacctg gctgcggctt
      481 tactcttttc tttggcacgc agttccagcg cgtagatagc accatgttca ggacagcacc
      541 agacaacgtt gctgtaagca ggaggaaacc attcccgaca aactttgcat ttacggcgcg
      601 gtaatttagc catgctcacc tcagacccgg ttacggatat agcatctaat aacgttagat
      661 tatgcatgcc tgaca
//
LOCUS       DAJVBX010000406          668 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.409, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000406 DAJVBX010000000
VERSION     DAJVBX010000406.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 668)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 668)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..668
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.409"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..>668
                     /locus_tag="OPV72_004521"
     CDS             <1..>668
                     /locus_tag="OPV72_004521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="shufflon system plasmid conjugative transfer
                     pilus tip adhesin PilV"
                     /protein_id="HCR9916628.1"
                     /translation="DLLGKAMQTAGIDSGMTKTTSIASGHSGQWSETSANFNNITSAG
                     QLAFRVGFNSALYSVYLRRDGTLPMTGDLNLDGHNINNVAALNATGNITTTGDVQARN
                     IKATGKIDADGNISAGNWMWAKNGYGDAIGFGGDGYSGGLGRDYEIKMLSNHPLTIHS
                     PTSSRGNDVILDIDGNMRVQTDISSLRNITASGNIESSQNVKGATLESTGRATVGEFV
                     QLNG"
BASE COUNT          214 a          116 c          157 g          181 t
ORIGIN      
        1 atgatttatt agggaaagcc atgcaaacag caggtataga tagcggtatg actaaaacaa
       61 catctattgc ttctgggcat agtggtcaat ggtcagaaac gtctgctaat tttaataata
      121 ttacatccgc tggacagtta gcatttagag ttggttttaa tagtgcgtta tattctgtat
      181 atttaagacg ggatggaacc ttgcccatga ctggcgatct aaatcttgac ggacacaata
      241 tcaacaatgt cgccgcactt aatgccactg gcaacattac gacgacaggt gacgtacagg
      301 caagaaacat taaggctact ggaaaaattg atgcggacgg taatatctca gccggtaatt
      361 ggatgtgggc taagaatgga tatggggacg ctataggttt tggtggagat ggatattctg
      421 gaggtttagg tcgagattat gaaataaaaa tgctatctaa ccatccacta acgatacatt
      481 caccaacgtc tagtcgcgga aatgatgtta tattagatat tgatggaaat atgagggttc
      541 agactgatat tagctctctt agaaacatta cagcctctgg aaacatagaa tcatcccaaa
      601 acgtcaaagg cgctacatta gaatccacag gacgcgctac ggtgggtgaa tttgttcaat
      661 tgaacgga
//
LOCUS       DAJVBX010000407          666 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.410, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000407 DAJVBX010000000
VERSION     DAJVBX010000407.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..666
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.410"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..>666
                     /locus_tag="OPV72_004522"
     CDS             <1..>666
                     /locus_tag="OPV72_004522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HCR9916629.1"
                     /translation="LGLRHWNNNVVKIPPPAESGANASDVVVDTPEPYERILCQKILM
                     GISTIDIIRNAIIKSCEQLNIEKERINELNEQNDKARSSLKSLVEFITEIGTTSSDIG
                     CRMGDLNTSLTQINACIKEIQKIANQTNLIAINSAIEAARVGDAGRGFSVISKEVKNL
                     SEDVKHSSKSVSTLTSVIKDNTARVSEVLDNQQPVIDNITTNINQIVESIGIVIDKSL
                     SMKS"
BASE COUNT          212 a          129 c          155 g          170 t
ORIGIN      
        1 attaggcttg cgccactgga ataataatgt tgtaaaaata ccgccgccag cagaatctgg
       61 cgctaatgcg tctgacgtgg tggtggatac tcctgagcct tatgagcgga tactgtgtca
      121 aaaaattctg atggggatct cgacgatcga tatcattcgt aatgccatca ttaagtcctg
      181 tgagcagctc aatattgaaa aagaacgcat taatgaactt aacgaacaga atgataaagc
      241 cagaagttca ttaaaatcgc tcgtggaatt tatcaccgaa attggcacga cttcatcaga
      301 tattggctgt cgtatgggcg acttaaatac ctccttaacg caaattaatg cgtgtattaa
      361 agagatacag aagatcgcta accagaccaa tttgatagcg attaactccg cgatcgaggc
      421 cgcgcgcgta ggggatgccg ggcgtggttt tagcgttatt tcgaaagaag tgaaaaacct
      481 gtccgaagat gttaaacaca gttcgaaaag cgtcagtacg ttaacctctg taatcaaaga
      541 taatacggcc agagtgagtg aggtgctgga taaccaacag ccggttattg ataatattac
      601 gactaacata aatcaaattg tggagtctat tggcatcgtc attgataaat cgctgagcat
      661 gaaatc
//
LOCUS       DAJVBX010000408          662 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.411, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000408 DAJVBX010000000
VERSION     DAJVBX010000408.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..662
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.411"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            233..634
                     /gene="spiC"
                     /locus_tag="OPV72_004523"
     CDS             233..634
                     /gene="spiC"
                     /locus_tag="OPV72_004523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPI-2 type III secretion system protein SpiC"
                     /protein_id="HCR9916630.1"
                     /translation="MSEEGFMLAVLKGIPLIQDIRAEGNSRSWIMTIDGHPARGEIFS
                     EAFSISLFLNDLESLPKPCLAYVTLLLAAHPDVHDYAIQLTADGGWLNGYYTTSSSSE
                     LIAIEIEKHLALTCILKNVIRNHHKLYSGGV"
BASE COUNT          209 a          107 c          139 g          207 t
ORIGIN      
        1 aaaaacatcg taacagttta tttaataaat aatttttcaa attgtaagtt tttgtgtcta
       61 tgctgaaaat gtaattgtga atttatcgga aaatccgaat gatagaatcg cctgtgacaa
      121 ggtatatgta gacagcatcc tgatattgta caagaagagt atagtcgaaa taaatgtgaa
      181 tcaggctttt tacggatgtg gttgtgagcg aatttgatag aaactcccat ttatgtctga
      241 ggagggattc atgctggcag ttttaaaagg cattccatta attcaggata tcagggccga
      301 aggtaatagc cgatcctgga taatgactat tgatgggcat cctgccagag gagaaatttt
      361 ctcagaagca ttttctattt ctttgttctt aaatgacctg gaaagcttac ctaagccttg
      421 tcttgcctat gtgacactac tgcttgcagc acacccggac gtccatgact atgctataca
      481 gctcacagcg gatgggggat ggttaaacgg ttattatacc acaagtagta gctctgagct
      541 tattgctatt gagatagaaa aacacctggc tttaacttgc attttaaaaa atgtaatacg
      601 caatcaccat aaactttatt cgggtggggt ataaaatggt agtaaataaa cgtttaatct
      661 ta
//
LOCUS       DAJVBX010000409          645 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.412, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000409 DAJVBX010000000
VERSION     DAJVBX010000409.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..645
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.412"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            21..>645
                     /locus_tag="OPV72_004524"
     CDS             21..>645
                     /locus_tag="OPV72_004524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012210136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916631.1"
                     /translation="MATTNAKKIEVSGELTTGSTLQIADVFIEDEDGDPLSLDKMNNA
                     DDIKWYLVDNEAADPSGTPAATGTAFTIPAYAGGKKIKIVYRIKTATGTPDSAFLPAT
                     VLLTSASSGVSGDSAADGTISNKLRSVTINVVNESGKPTDELNGTNDANTPVVGGTLE
                     VVLECAATAAAECEVSNYNFTWQMADAGTPDRFTDLNNTNAEKHKYII"
BASE COUNT          175 a          144 c          168 g          158 t
ORIGIN      
        1 cttctgttgg tcaccgtcct gtggcaacta ctaatgcaaa aaagatagaa gtgtctgggg
       61 aactgacgac cggttcaacc ctccagatag cggatgtttt tattgaggat gaggatgggg
      121 atcccttatc gctggataaa atgaataatg ccgacgatat taaatggtat ctggtggata
      181 atgaggccgc cgatccttct ggaaccccgg cggcaaccgg gacggctttt accattcctg
      241 cttatgcagg cggtaaaaaa attaaaatcg tttaccggat taagacggca acggggacgc
      301 cggatagtgc attcttgcct gccactgtct tattaacttc tgcatcttct ggggtgagcg
      361 gcgactccgc cgcagacggt acaatttcta ataagctacg ttctgtcact atcaatgtgg
      421 tgaatgaaag tggtaaaccg actgatgaac tcaacggtac caatgacgcc aacactccag
      481 tggtaggcgg cacccttgaa gtggtactgg aatgtgccgc cacagcggcg gctgagtgtg
      541 aggtcagtaa ttataacttt acctggcaga tggcggatgc cgggacacca gataggttca
      601 ccgatctgaa taataccaac gctgaaaagc ataaatatat tatta
//
LOCUS       DAJVBX010000410          641 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.413, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000410 DAJVBX010000000
VERSION     DAJVBX010000410.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..641
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.413"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(91..486)
                     /locus_tag="OPV72_004525"
     CDS             complement(91..486)
                     /locus_tag="OPV72_004525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001731400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polymerase"
                     /protein_id="HCR9916632.1"
                     /translation="MPRAIWPDKPEDFGALYLAKVFFPDAFYRNQGAPAFGYGELYAD
                     FGLFTPVWLVISGVFKGVLAKYFSNKTQETKSAHYFIMFLFCIGISVIPVSMGWLFPE
                     HLMIAFMVYIASSFVFSEHIRFVLLRNNK"
BASE COUNT          225 a          138 c          112 g          166 t
ORIGIN      
        1 taatgatggc tcagcaaacc caacaagctt tacaggaaca atttttacgc ttcagagcca
       61 aataaaacgg cggcattgcc gccgtataac ttatttattg tttcttagta aaacgaatct
      121 tatatgctct gaaaaaacaa aggaagatgc aatgtatacc ataaaagcaa tcatcaaatg
      181 ctcagggaac aaccatccca tgctaacagg aatcacactt attccaatgc aaaataggaa
      241 cattatgaaa taatgcgctg actttgtttc ctgagtttta ttggagaaat acttagctag
      301 gacgccttta aatactccag atataactaa ccaaactggt gtaaaaagcc cgaaatctgc
      361 gtatagttca ccatacccga aagcaggagc gccctgattt ctgtagaatg catcagggaa
      421 aaatactttt gccagataca atgcgccaaa atcttcaggc ttatcaggcc aaatagccct
      481 cggaatcctc gagtaaacct cgctctccat tagtaatttt ccgtacataa agtcaaagtt
      541 tgaggaagca acaagaacag cattacgggt ataatccgag taattagcca tattttctat
      601 cggattccca tcagtaaacg tatatgcaaa gaatgccgtt a
//
LOCUS       DAJVBX010000411          634 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.414, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000411 DAJVBX010000000
VERSION     DAJVBX010000411.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..634
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.414"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            118..616
                     /locus_tag="OPV72_004526"
                     /pseudo
     CDS             118..616
                     /locus_tag="OPV72_004526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789648.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Saf-pilin pilus formation protein SafA"
BASE COUNT          184 a          110 c          161 g          179 t
ORIGIN      
        1 attaagtatt attaagtctt aaagtattcc cagccacagg cttttctgta cggtgaattt
       61 tggtatgaca ttattcattc ttgatgtgct gggggatttt gaaaaggtgg atttccgatg
      121 aaaaacataa aagatttaat tatcgcaagc gcattgagca ttatggctgc tagttgttat
      181 gctggctcgc tcgtgccgaa tacaagcact ggcgtgtcgg cggatgtaaa cttcagcaat
      241 cctggacaac tacaagcaca gcttactcca gtgtctggct tggtggcagg gcctcataag
      301 ggtgatgagg ctattgctat actttcggca agcggttcga gcaaacaata cgtggtaacg
      361 ggagattatt ctaaacctga aaacagtggg caacgacagc gatgtgtgga cggtaattgg
      421 taaaagtggt aataccatta aaattacctt tgggggggta gcctgtggct caaaaggttc
      481 attagtggat ggtgcttcgc ataagtggtg gatatataac atgacagaca aagtcgctgt
      541 gaaattgtct ggatcacaaa cggtaaaggc tgatacttat ccagtgacga tacacatagc
      601 ggagtatcaa gcttaatagt aaacaacttt tatt
//
LOCUS       DAJVBX010000412          616 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.415, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000412 DAJVBX010000000
VERSION     DAJVBX010000412.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..616
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.415"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            62..577
                     /gene="ompX"
                     /locus_tag="OPV72_004527"
     CDS             62..577
                     /gene="ompX"
                     /locus_tag="OPV72_004527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein OmpX"
                     /protein_id="HCR9916633.1"
                     /translation="MKKIACLSALAAVLAFSAGTAVAATSTVTGGYAQSDAQGVANKM
                     SGFNLKYRYEQDDNPLGVIGSFTYTEKDRTNGAGDYNKGQYYGITAGPAYRLNDWASI
                     YGVVGVGYGKFQTTDYPTYKHDTSDYGFSYGAGLQFNPMENVALDFSYEQSRIRSVDV
                     GTWIAGVGYRF"
BASE COUNT          150 a          147 c          157 g          162 t
ORIGIN      
        1 tcccattaat ttttgatata tttaaaactt aggacttact tgaagcacat ttgaggtggt
       61 tatgaaaaaa attgcatgtc tttcagcact ggccgctgtt ctggcttttt ccgcaggtac
      121 tgcagtagct gctacttcta ctgttaccgg tggttacgct cagagcgacg cgcagggcgt
      181 agcgaataaa atgagcggtt tcaacctgaa gtatcgttac gagcaggacg acaacccgct
      241 gggtgtaatc ggttccttca cctacaccga aaaagatcgt actaacggtg cgggcgatta
      301 caataaaggt cagtactacg gcatcactgc cggcccggct taccgtctga acgattgggc
      361 gagcatctac ggtgtagtcg gtgtgggtta cggtaaattc cagacgaccg attacccaac
      421 ctacaaacat gacaccagcg attatggctt ctcctatggc gctggtctgc aattcaaccc
      481 gatggaaaat gttgctctgg acttctctta cgagcagagc cgtattcgta gcgttgacgt
      541 tggcacctgg attgctggcg taggttaccg cttctaatca cgtcggtgaa aatgaaaaat
      601 ccgcctttcg gggcgg
//
LOCUS       DAJVBX010000413          614 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.416, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000413 DAJVBX010000000
VERSION     DAJVBX010000413.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..614
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.416"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..154
                     /locus_tag="OPV72_004528"
     CDS             <1..154
                     /locus_tag="OPV72_004528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916634.1"
                     /translation="LSHFQRGVEKYAHEYGLDEEAKKRLEDLDVKVVSTVKEFFSAEV
                     ISWEPK"
     gene            151..>614
                     /locus_tag="OPV72_004529"
     CDS             151..>614
                     /locus_tag="OPV72_004529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916635.1"
                     /translation="MKNIHSVTDKALYDALNQKQITLNEIQDLFLERGTIICKKTPRK
                     ELARNYSRMTHDYYEHQKIATLLGGQTRTEKITCVRIETGIDKKGIIDAAEKLKKEIT
                     GQDDYCKIIVDGPRVLINIRYLSTNYGKSDFKQAINKEALIEIEPLDDGYSIR"
BASE COUNT          228 a           88 c          131 g          167 t
ORIGIN      
        1 tctctcccat tttcaacggg gagttgaaaa atatgcgcat gagtatgggt tagatgaaga
       61 agctaaaaag aggcttgaag atttagacgt taaagttgtg tctacagtaa aagaattctt
      121 ctctgcagaa gttatttctt gggagccgaa atgaaaaata ttcacagcgt aactgataaa
      181 gctttgtatg atgctttaaa ccaaaagcaa attaccctaa atgaaattca agaccttttc
      241 ttagagagag gaacgattat atgtaaaaaa actcctcgaa aggaattggc aagaaactat
      301 tctcgaatga ctcatgatta ttacgagcat caaaaaattg caaccctgct aggtggccag
      361 acaaggaccg aaaaaattac atgtgtaaga attgagactg gtatagataa gaaaggtatt
      421 atagacgcgg cagaaaaact taagaaagaa attaccgggc aggatgatta ttgtaaaata
      481 atcgtggatg ggccgcgagt tctgattaat attagatatc tttcaactaa ttatggaaaa
      541 agtgatttca aacaggctat taataaagag gcgttaattg aaattgagcc tcttgatgat
      601 ggttacagta tccg
//
LOCUS       DAJVBX010000414          610 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.417, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000414 DAJVBX010000000
VERSION     DAJVBX010000414.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..610
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.417"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..297)
                     /locus_tag="OPV72_004530"
     CDS             complement(<1..297)
                     /locus_tag="OPV72_004530"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916636.1"
                     /translation="MGSTVSSLDNTVSLKGVVEAHQDIQVKVTVDDTDYTASVDNDTG
                     NWHVSVPQSAILSGENQYTITATDPAGNSAAASVTFTGTSPTENPVNKSSGVDEM"
     gene            complement(354..551)
                     /locus_tag="OPV72_004531"
     CDS             complement(354..551)
                     /locus_tag="OPV72_004531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001787491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916637.1"
                     /translation="MVGKATLDIIFRDRSANAMDNSSLSIGWLTIDSTPPVRSMKNNS
                     DIGAGGDNITNINTPTFYWVA"
BASE COUNT          150 a          146 c          146 g          168 t
ORIGIN      
        1 catttcatct acgccggaac tcttgttgac cggattttcc gtgggcgatg tacctgtaaa
       61 tgttacactg gcggcggcgc tattaccggc gggatcggtg gccgttatgg tatactgatt
      121 ctcccccgac agaatagcgg attgcggaac agaaacatgc cagttaccgg tatcgttatc
      181 gacactggcg gtgtagtccg tatcgtcgac cgtgaccttc acctgaatat cctgatgcgc
      241 ctccacgact cccttaaggc tgacggtatt atccagactg ctaacagtcg atcccaacgt
      301 tggttcggcg gacggttgtg tatcaatagt cagcttaatt gttgcgtgag cttctaagcg
      361 acccaataaa aggtcggtgt attgatgtta gtgatattat cgcctccggc gccaatatca
      421 ctattattct tcatggaacg tactggcggt gtagagtcta tcgtcagcca gccgatagac
      481 agcgaagaat tatccatagc gtttgcggaa cgatctctga agatgatatc cagagttgcc
      541 ttgcctacca ttctagcaac attttagaaa aaattacgta atatcgactg atatgtaaaa
      601 ctcattcagc
//
LOCUS       DAJVBX010000415          595 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.418, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000415 DAJVBX010000000
VERSION     DAJVBX010000415.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..595
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.418"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            130..>595
                     /locus_tag="OPV72_004532"
     CDS             130..>595
                     /locus_tag="OPV72_004532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin-like domain-containing protein"
                     /protein_id="HCR9916638.1"
                     /translation="MNIKTVEDLFIHLLSDTYSAEKQLTKALPKLARATSNEKLSQAF
                     QSHLEETQGQIERIDQIVESESGIKLKRMKCVAMEGLIEEANEVIESTEKNEVRDAAL
                     IAAAQKVEHYEIASYGTLATLAEQLGYSKALKLLKETLDEEKQTDLKLTDLAV"
BASE COUNT          202 a          133 c          121 g          139 t
ORIGIN      
        1 tcagaatagt cacggcggac gtaaatccga taattcctga tttactgtaa tgtaaatata
       61 acacatgctt ttatcaagca atctgcgagt cttctggctc gcagtatttt gcccaggaga
      121 attagattta tgaatatcaa aaccgttgaa gaccttttta tccatctact ttcagatacc
      181 tatagtgcag aaaaacaatt aaccaaggct cttcctaaac ttgccagagc cacgtccaat
      241 gaaaaattaa gccaggcctt tcaatctcat cttgaagaaa cccagggtca gattgaacgt
      301 attgatcaga tcgtcgaatc tgaatctggc attaaactga aaagaatgaa atgcgtcgct
      361 atggaagggc tgattgaaga agccaatgaa gtcatcgaaa gtacggagaa aaacgaagta
      421 cgcgatgcag cgcttatcgc cgcggcgcaa aaagtcgagc attacgaaat cgccagctac
      481 ggcacgctag ccaccctggc cgagcagctc ggctatagca aagcattaaa actgctcaaa
      541 gaaaccctcg acgaggaaaa acaaactgat ttaaaactta ccgatttagc agtca
//
LOCUS       DAJVBX010000416          594 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.419, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000416 DAJVBX010000000
VERSION     DAJVBX010000416.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 594)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 594)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..594
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.419"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..>594
                     /locus_tag="OPV72_004533"
     CDS             <1..>594
                     /locus_tag="OPV72_004533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="UDP-phosphate galactose phosphotransferase"
                     /protein_id="HCR9916639.1"
                     /translation="DQLDTRVITHFILSVVCVGWFWIRLRHYTYRKPFWYELKEIFRT
                     IVIFAIFDLALIAFTKWQFSRYVWVFCWTFAIILVPFFRALTKHLLNKLGIWKKKTII
                     LGSGQNARGAYSALQSEEMMGFDVIAFFDTDASDAEINMLPVIKDTGTIWDLNRTGDV
                     HYILAYEYTELEKTHFWLRELSKHHCRSVSVVPSFRG"
BASE COUNT          154 a           93 c          137 g          210 t
ORIGIN      
        1 agaccaatta gatacaagag ttattactca ttttattttg tcagtagtat gtgtcggttg
       61 gttttggatt cgtttgcgac attatacata ccgcaagcca ttttggtatg agttaaaaga
      121 aatttttcgt acgatagtta tttttgctat atttgatttg gctctgatag cgtttacaaa
      181 atggcagttt tcacgctatg tctgggtgtt ttgttggact tttgccataa tcctggtgcc
      241 tttttttcgc gcacttacaa agcatttatt gaacaagcta ggtatctgga agaaaaaaac
      301 tatcatcctg gggagcggac agaatgctcg tggtgcatat tctgcgctgc aaagtgagga
      361 gatgatgggg tttgatgtta tcgctttttt tgatacggat gcgtcagatg ctgaaataaa
      421 tatgttgccg gtgataaagg acactgggac tatttgggat ttaaatcgta caggtgatgt
      481 ccattatatc cttgcttatg aatacaccga gttggagaaa acacattttt ggctacgtga
      541 actttcaaaa catcattgtc gttctgttag tgtagtcccc tcgtttagag gatt
//
LOCUS       DAJVBX010000417          584 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.420, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000417 DAJVBX010000000
VERSION     DAJVBX010000417.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..584
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.420"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..>584)
                     /gene="sopF"
                     /locus_tag="OPV72_004534"
     CDS             complement(<1..>584)
                     /gene="sopF"
                     /locus_tag="OPV72_004534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="type III secretion system effector SopF"
                     /protein_id="HCR9916640.1"
                     /translation="GDLPAYNVGRDSVETKAFELEKLADSPYAPYGQTGGFSVAYTPN
                     SKTFSPTSRPIYAALDFLNGENGGASAYGKSFFELNDNVKTNCTFSPFDIYGHRFGLD
                     TSKLSTFCHMENLIASCQNDFFGYNCFKSLVKMAKGEKFLAHSNYGTGYEGNYIEAHI
                     HGDVCLFRDIKHVYLSLLENSYSESQLYDYAKQI"
BASE COUNT          189 a          115 c           98 g          182 t
ORIGIN      
        1 tatttgtttt gcataatcat atagttgact ttccgagtaa gagttttcta gcaaagacaa
       61 ataaacgtgc tttatatctc tgaataaaca tacatcacca tgaatatgag cctctatata
      121 attcccttca tagcctgtac cataattaga atgagctaaa aatttttcgc ccttagccat
      181 tttaaccaaa ctcttaaagc aattataacc aaaaaaatca ttttgacagg atgcaatcag
      241 gttctccata tggcaaaatg tagataattt actagtatcc aggccaaatc tgtggccgta
      301 gatatcaaaa ggtgagaatg tacaatttgt ttttacatta tcatttaatt caaaaaatga
      361 tttcccatag gcgctggcac ctccattttc accgttcaga aagtccagtg cagcataaat
      421 tggtctgctt gtagggctaa aagttttact gttgggagta tatgctacgg aaaaaccgcc
      481 tgtctgacca tatggggcat aaggtgaatc tgcaagcttc tccagttcaa atgctttagt
      541 ttcaactgaa tcacgcccga cattataagc aggtaaatct cctg
//
LOCUS       DAJVBX010000418          579 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.421, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000418 DAJVBX010000000
VERSION     DAJVBX010000418.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 579)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 579)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..579
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.421"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(164..>579)
                     /locus_tag="OPV72_004535"
     CDS             complement(164..>579)
                     /locus_tag="OPV72_004535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000142761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CdiI family contact-dependent growth inhibition
                     immunity protein"
                     /protein_id="HCR9916641.1"
                     /translation="LGRYSSDPDYPCQLLSIDSDDVCIGHELLQALKNSRTYTPEESE
                     EYLSLEKTQVEYDEWVTVLMAKYNYRTRRALFKNMKYCSIICVNNIIKIQPTRHTKLE
                     GWSWAGHDKDVIRLPVTSEPEKIGSALRQAFECCD"
BASE COUNT          189 a          123 c           73 g          194 t
ORIGIN      
        1 ctccaactta caatctttta tatttttaat atccataggt aagcaataac agggaaaaaa
       61 catcaaaaaa agcataacta tttttaacat caatcagacc ttacaacaat tgtaaattta
      121 ttgtcttatt tctatcaaac ataaataacc tatcatcagg ctattaatca caacattcaa
      181 atgcctgtct caatgcactt ccaattttct ctggttcgct ggtaacaggc aatctaatta
      241 catctttgtc atgtccggcc cagctccacc cttcaagttt agtatgtcga gtaggttgta
      301 tcttaataat attattcacg catataattg agcaatactt catgttttta aataatgcac
      361 gcctggttct ataattatat tttgccatca atacagtgac ccactcatca tactccacct
      421 gtgttttctc taaagaaaga tactcttcac tctcttctgg ggtgtaagtt ctgctatttt
      481 ttaatgcttg taataattca tgaccgatac atacatcatc cgaatcaata gataataact
      541 gacaagggta atcaggatct gaagaatagc gccccaatc
//
LOCUS       DAJVBX010000419          569 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.422, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000419 DAJVBX010000000
VERSION     DAJVBX010000419.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..569
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.422"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..387)
                     /locus_tag="OPV72_004536"
     CDS             complement(<1..387)
                     /locus_tag="OPV72_004536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HCR9916642.1"
                     /translation="MKPASVIIMDEHPIVRMSIEVLLGKNSNIQVVLKTDDSRTAIEY
                     LRTYPVDLVILDIELPGTDGFTLLKRIKSIQEHTRILFLSSKSEAFYAGRAIRAGANG
                     FVSKRKDLNDIYNAVKIILSGYSFFPS"
BASE COUNT          173 a          112 c          113 g          171 t
ORIGIN      
        1 agatggaaaa aaagaatagc cggataaaat tatttttacc gcattataaa tatcattgag
       61 gtctttgcgt ttacttacaa atccgtttgc gcccgctctt attgctcttc cggcataaaa
      121 agcctctgat ttcgacgata aaaaaagtat ccgggtatgt tcctggatag atttgattcg
      181 tttaagtaag gtaaagccgt cggtgcccgg taattcaata tccagaatga caagatcaac
      241 aggataagtg cgcagatact ctatcgctgt tcggctatca tccgttttca ggacaacctg
      301 aatattgcta tttttaccga gtaaaacttc gatcgacatt cttacaatag ggtgttcgtc
      361 cataatgata acagatgcag gtttcattgt tgtatgcctc agactgttat gcgtccttcg
      421 ttttagaata agcgtcagac accttaaaga ttgtgaaata gccagatcta cacaccacac
      481 ggtggagcaa taataaagaa tgagacctcc ctgttgactg gctattttgc gtaagagtaa
      541 taaatatgtg gaatatccat ttcgcacca
//
LOCUS       DAJVBX010000420          556 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.423, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000420 DAJVBX010000000
VERSION     DAJVBX010000420.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..556
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.423"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
BASE COUNT          146 a          141 c          123 g          146 t
ORIGIN      
        1 cccctgaata aaaaccggag atgatgccag ttagccgtta tctctgcatt ttcataaacg
       61 ttggttttca agaaccaata aatcgtgtgg ctggtgcgct ataaaaatcg cagagcggtg
      121 acgatagtcc gcataaggag ctgttcgttc gcaacattcg aacggtgacg ttaaagccgg
      181 tttcattggc taatgaagac gaaggggaca aaattactac agagttgata ccacagagat
      241 agtccaggtt cgcaggtgat acgggattta acgccggaaa gtctgcacag acacgatctg
      301 ccgccggaca ccattaaatt gccccgcaac gtgttatcaa tactactccc tgcgtttccc
      361 gttaccttgc tgtcggtacg tttaccgcat tgtctgaaag gttatttgcg aagttatcat
      421 taataatcca cgggcgtctg gtatgcgaat ccagttcccc aatcctggcg ttttgccttc
      481 tcgaccatac gcgcgtaaat aagcctgaaa ccaaacttca ccgcttaacg ctctcctctt
      541 ccccgatttt tacgca
//
LOCUS       DAJVBX010000421          556 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.424, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000421 DAJVBX010000000
VERSION     DAJVBX010000421.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..556
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.424"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
BASE COUNT          162 a          118 c          111 g          165 t
ORIGIN      
        1 gaatatgtga atcactaccg taggataatg gctaattagt aaccactttt aaacatggtt
       61 aatcctattt ttaaagaaaa gttcgaactg tctgaattgt cgttgttgag tgtttaaatg
      121 ttttgcttta ttaagtgacc caggtagaat tcgcagcggc tggtaaccat tcatattcgc
      181 attattgaac gatcaccggc caaccgcgcc agggtcttgc atacgctctg gcgcggttaa
      241 atccccaggc cataaacgaa atcactggtt tctgttattg ctcgtatctt tcaagttaac
      301 ctgcattatg cttgcccacc tgatgtaaaa acacagctct gaaccatagg gtgtgaattt
      361 cattttataa aaaattgcgg tgccgggtgc ctcccggtgg accataccac agtcaatatg
      421 gttcgcgagg aacattaact atttgactgg acgccccgcc gcaaaggggg attcaccgca
      481 taagaaaaat ctacaactca caagtaataa aagacaataa catttttgtg cattttttat
      541 aaatgactat cttgtc
//
LOCUS       DAJVBX010000422          552 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.425, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000422 DAJVBX010000000
VERSION     DAJVBX010000422.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 552)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..552
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.425"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            1..432
                     /locus_tag="OPV72_004537"
                     /pseudo
     CDS             1..432
                     /locus_tag="OPV72_004537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343613.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          157 a          130 c          136 g          129 t
ORIGIN      
        1 ctcacagctc ttgcggctga actggctaaa ggtcttaaaa ctgaagccga cctcagtcag
       61 tttttccata tgctgacgaa attaaccgtc gaaacggcgc tcaatgctga gctggctgac
      121 catctcgggc atgagaaaaa tgctcctaaa acgagctcaa actcccacaa tggctactca
      181 ttaaaaacgg tgctgtatga tggcggcgag atagtgctga acatgctgcg tggccgtgaa
      241 aatacctttg aactgtagct gattaaggag catcagacgc gtattacgag atggaaagtc
      301 agatttatcc ctttatgcca aaggcatgac atgactaccc gcgaaatcat cgccaccttc
      361 aaagagatgt acgacgctga tgtgtcgccc atgctgatac ttaagatcac cgccgcagta
      421 aaagagttgg tcaaaggggc gtcaaaaaat ggagtatgcc gatccaggac tggtcgctgg
      481 caatgattcg ctttattatc gagttcggtg accgcctgag cgatcaccgt taatatagtg
      541 gcagttacac ag
//
LOCUS       DAJVBX010000423          551 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.426, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000423 DAJVBX010000000
VERSION     DAJVBX010000423.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 551)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 551)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..551
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.426"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..503
                     /locus_tag="OPV72_004538"
     CDS             <1..503
                     /locus_tag="OPV72_004538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR9916643.1"
                     /translation="RQNGFVLSGFNVRILRNGLGKVDIVPLQVNFGHIYTTYEPSQTR
                     QANFTVIARQVLRPAMGQEFAIPLAITFGKGALTQDTGQTLNLVSLDGPNKGQPNGLR
                     LSIKDDKGKEITFDKQEVLGDITITGTVTGNVSKVYTAVITPTLGGSVKTGKFSAAIL
                     VTVTYN"
BASE COUNT          171 a          104 c          135 g          141 t
ORIGIN      
        1 tgagacaaaa cggatttgtt ttatctggtt ttaatgtgag aattctcaga aacggattgg
       61 gtaaagttga cattgttcca ttacaggtca actttgggca tatttatacg acttatgaac
      121 cttcacagac cagacaggca aattttacag tgatcgccag gcaggtttta cgaccggcta
      181 tgggacagga attcgcgatc ccgctggcca tcaccttcgg gaaaggtgcg ctgacacagg
      241 ataccgggca aactctgaat cttgtcagtc tggatggccc caacaaaggt cagcctaatg
      301 gactccggct ttcaataaaa gatgataaag gaaaagagat tacttttgat aaacaagaag
      361 tactggggga tattactatt acaggaactg tcaccggtaa tgtgtcgaag gtatatactg
      421 cagtaataac cccgaccctg gggggaagtg taaagacagg aaagttttct gctgcaatac
      481 tcgttactgt tacctataac taatcggggg tgacagataa taaaaataaa agagctgact
      541 gagttatcgg g
//
LOCUS       DAJVBX010000424          529 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.427, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000424 DAJVBX010000000
VERSION     DAJVBX010000424.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..529
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.427"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..>529)
                     /gene="rfaJ"
                     /locus_tag="OPV72_004539"
     CDS             complement(<1..>529)
                     /gene="rfaJ"
                     /locus_tag="OPV72_004539"
                     /EC_number="2.4.1.58"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="lipopolysaccharide 1,2-glucosyltransferase RfaJ"
                     /protein_id="HCR9916644.1"
                     /translation="VVLNNNIPLAFHIICDSYSPCFVKYIERLAVQHHIKISLYLIKV
                     ESLEVLPQTKVWSRAMYFRLFAFDYLSKKVNTLLYLDADVVCKGSLQDLLQLDLTEKI
                     AAVVKDVDSIQNKVNERLSAFNLQGGYFNSGVVFVNLKLWKENALTEKAFLLLAGKEA
                     DSFKYPDQDVLNILL"
BASE COUNT          184 a           99 c           88 g          158 t
ORIGIN      
        1 tgtaggagaa tattcaaaac atcctgatcg ggatatttaa aagagtcagc ttctttacct
       61 gccagaagta aaaatgcctt ttcagttaag gcattctctt tccataattt caggttaaca
      121 aaaaccacgc cggagttaaa ataaccacct tgtaaattaa aagcgcttaa tctctcattt
      181 accttattct ggatggaatc aacatctttt actaccgcag caatcttctc tgtcagatca
      241 agctgtagaa gatcttgcaa agatccttta catacaacat cggcatccaa ataaagtaag
      301 gtgtttacct tcttgctgag ataatcgaaa gcaaataaac gaaaatacat tgctctcgac
      361 catactttag tttggggcaa tacttcaagg ctttctactt taataagata aagagaaatt
      421 ttaatgtgat gctgtacggc taaacgctct atatatttta caaaacacgg ggagtatgag
      481 tcacaaataa tatgaaaagc aagcgggata ttattgttta atacaacgg
//
LOCUS       DAJVBX010000425          517 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.428, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000425 DAJVBX010000000
VERSION     DAJVBX010000425.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..517
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.428"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(5..>517)
                     /locus_tag="OPV72_004540"
     CDS             complement(5..>517)
                     /locus_tag="OPV72_004540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001388200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber protein"
                     /protein_id="HCR9916645.1"
                     /translation="PVGVPVPWPSATPPAGWLKCNGAAFSSEMYPNLAKAYPTNKLPD
                     LRGEFIRGWDDGRGVDAGRALLRLQDDSFEAHRHESFFYAGISRNEIPLKNLPSSDEM
                     LTLSSTTNALSPDGIDATNSLIGNDDYNCLIEGNKNNKRTATGLSTSIVGATETRPRN
                     IAFNYIVRAA"
BASE COUNT          127 a          126 c          124 g          140 t
ORIGIN      
        1 gtttctatgc cgcccttacg atgtaattaa acgcaatgtt acgggggcgg gtttcagttg
       61 cgccgacaat actggtactt agacccgttg ctgttcgttt gttattttta ttcccttcga
      121 tcagacagtt gtaatcgtca ttaccaatta acgaattggt ggcatcaata ccgtccggtg
      181 acaaggcatt agttgtggaa cttaaagtca gcatctcgtc tgaacttgga agatttttta
      241 atgggatttc attgcgtgaa atacccgcat aaaaaaagga ctcatgcctg tgcgcttcaa
      301 aagagtcatc ctgaagcctt agcaaggctc gccccgcatc cacgccacgt ccgtcatccc
      361 agccacggat aaattcaccc cgtagatccg gtagtttatt tgtaggataa gcctttgcca
      421 gattggggta catttcagaa gaaaatgctg cgccgttaca tttcagccac cctgctggcg
      481 gtgtggctga gggccacgga acgggcacac caacggg
//
LOCUS       DAJVBX010000426          492 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.429, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000426 DAJVBX010000000
VERSION     DAJVBX010000426.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.429"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..161)
                     /gene="tomB"
                     /locus_tag="OPV72_004541"
     CDS             complement(<1..161)
                     /gene="tomB"
                     /locus_tag="OPV72_004541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001741190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hha toxicity modulator TomB"
                     /protein_id="HCR9916646.1"
                     /translation="MDEYSPKRHDIAQLKFLCETLYHDCLANLEESNHGWVNDPTSAV
                     NLQLNELIE"
BASE COUNT          142 a           98 c           90 g          162 t
ORIGIN      
        1 tgctctatca gctcattgag ctgcaggttg actgctgagg tcgggtcatt aacccagcca
       61 tggttgcttt cttcaaggtt tgcaagacag tcatgataca gggtttcgca aagaaattta
      121 agctgtgcta tatcatgtct tttgggtgag tattcgtcca taatgcatcc cctttttagt
      181 ggcttaaact aaccgaacac cttcgggatg gatacaacta actaacctgg tacttcccac
      241 gtcaccttat gatttaacta taatctactc taaaaaactt ttcatcgtca tattactaaa
      301 aattacaatt gcgtgaaagc cgtgtgtcgc catacttttt cgaattttaa cagtgaacgt
      361 cggtcgccta aaaaggaacc agttttattg ctcgtataat cattgggtta acgtttttta
      421 gcttttcagg ctaaaacaat agactctgac aggagaaaat agctaggaat attcttaata
      481 tttcttaatt aa
//
LOCUS       DAJVBX010000427          478 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.430, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000427 DAJVBX010000000
VERSION     DAJVBX010000427.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 478)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.430"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..86
                     /locus_tag="OPV72_004542"
     rRNA            <1..86
                     /locus_tag="OPV72_004542"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            156..232
                     /locus_tag="OPV72_004543"
     tRNA            156..232
                     /locus_tag="OPV72_004543"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:190..192,aa:Ile,seq:gat)
     gene            344..419
                     /locus_tag="OPV72_004544"
     tRNA            344..419
                     /locus_tag="OPV72_004544"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:377..379,aa:Ala,seq:tgc)
BASE COUNT          121 a          110 c          125 g          122 t
ORIGIN      
        1 gggcgcttac cactttgtga ttcatgactg gggtgaagtc gtaacaaggt aaccgtaggg
       61 gaacctgcgg ttggatcacc tccttacctt aaagaagcgt actttgcagt gctcacacag
      121 attgtctgat gaaaaacgag cagtaaaacc tctacaggct tgtagctcag gtggttagag
      181 cgcacccctg ataagggtga ggtcggtggt tcaagtccac tcaggcctac cagattttcc
      241 ctgaatactg cgttgtgaaa taactcacat actgatgtat gcttcgttat tccacgcctt
      301 gtctcaggaa aaattatcgg taaagaggtt ctgactacac gatggggcta tagctcagct
      361 gggagagcgc ctgctttgca cgcaggaggt ctgcggttcg atcccgcata gctccaccat
      421 ctcgtgagtg tttacgaaaa aatacttcag agtgtacctg aaagggttca ctgcgaag
//
LOCUS       DAJVBX010000428          470 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.431, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000428 DAJVBX010000000
VERSION     DAJVBX010000428.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 470)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 470)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..470
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.431"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..>470
                     /gene="tuf"
                     /locus_tag="OPV72_004545"
     CDS             <1..>470
                     /gene="tuf"
                     /locus_tag="OPV72_004545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462349.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HCR9916647.1"
                     /translation="ATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVE
                     MEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWEAKIIELAGFLDSYIPEPERAIDK
                     PFLLPIEDVFSISGRGTVVTGRVERGIIKVGEEVEIVGIKETQKSTCTGVEMFR"
BASE COUNT          108 a          116 c          137 g          109 t
ORIGIN      
        1 gcgactgacg gcccgatgcc gcagacccgt gagcacatcc tgctgggtcg tcaggtaggc
       61 gttccgtaca tcatcgtgtt cctgaacaaa tgcgacatgg ttgatgacga agagctgctg
      121 gaactggttg aaatggaagt tcgtgaactt ctgtctcagt acgacttccc gggcgacgac
      181 acgccgatcg ttcgtggttc tgctctgaaa gcgctggaag gcgacgcaga gtgggaagcg
      241 aaaatcatcg aactggctgg cttcctggat tcttacatcc cggaaccaga gcgtgcgatt
      301 gacaagccgt tcctgctgcc gatcgaagac gtattctcca tctccggtcg tggtaccgtt
      361 gttaccggtc gtgtagaacg cggtatcatc aaagtgggcg aagaagttga aatcgttggt
      421 atcaaagaga ctcagaagtc tacctgtact ggcgttgaaa tgttccgcaa
//
LOCUS       DAJVBX010000429          432 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.432, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000429 DAJVBX010000000
VERSION     DAJVBX010000429.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..432
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.432"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            <1..>432
                     /locus_tag="OPV72_004546"
     CDS             <1..>432
                     /locus_tag="OPV72_004546"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="E3 ubiquitin--protein ligase"
                     /protein_id="HCR9916648.1"
                     /translation="NKRILSAERKNTLNNTLLTVKNIKDTNNTYKKNISEEDVSKMTA
                     ALMRKHIANQSCDYNYRVTGAAPLPGEVSVSANNRPTVSEGRTPPVSPSLSLQATSSP
                     SSPADWAKKLTDAVLRQKAGETLTPADRDFSNADFRNITFS"
BASE COUNT          151 a          102 c           74 g          105 t
ORIGIN      
        1 aaaataaaag aattctttca gccgaaagaa aaaatacctt aaacaataca ttgcttactg
       61 ttaaaaatat taaagataca aataatacat ataagaaaaa tatttcagaa gaagatgtct
      121 caaaaatgac tgcagcactc atgcgtaagc atattgcaaa tcaatcatgt gattataatt
      181 acagagtgac aggtgcagcc ccgctccccg gtgaagtctc tgtatcagcc aataacaggc
      241 caacggtttc tgaaggtaga acaccaccag tatcaccctc cctctcactt caggctacgt
      301 cttccccgtc atcacctgcc gactgggcta agaaacttac ggatgcagtt ttacggcaga
      361 aagccggaga aactcttacg cccgcagatc gcgatttttc aaacgcagat ttccgtaata
      421 ttacattcag ca
//
LOCUS       DAJVBX010000430          419 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.denovo.433, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000430 DAJVBX010000000
VERSION     DAJVBX010000430.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..419
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.denovo.433"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            68..>419
                     /gene="pmrG"
                     /locus_tag="OPV72_004547"
     CDS             68..>419
                     /gene="pmrG"
                     /locus_tag="OPV72_004547"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide core heptose(II)-phosphate
                     phosphatase"
                     /protein_id="HCR9916649.1"
                     /translation="MLAFTLRFIKNKRYFAILAGALVIIAGLASQHAWSGNGLPQING
                     KALAALAKQHPVVVLFRHAERCDRSDNTCLSDSTGITVNGAQDARALGKAFSADIQNY
                     NLYSSNTVRTIQSAT"
BASE COUNT           95 a          104 c          113 g          107 t
ORIGIN      
        1 cgtcgcggaa tttcatttta atcgtattgc tattaagtta gctgcactgt ctgcctgaga
       61 ggttaatgtg ctggcattta ccctacgctt tattaaaaac aaacgctatt tcgcgattct
      121 ggcgggggcg ttggttatta tcgctgggtt ggcctcacaa catgcctgga gcggtaacgg
      181 tctaccgcag attaacggta aggcgctggc ggcgctggcg aagcagcatc cggtagtcgt
      241 gttattccgc catgccgagc ggtgcgatcg ttccgataat acctgcctgt cagacagcac
      301 ggggattacg gtcaacggtg cgcaagatgc cagagcgctg ggtaaagcct tcagtgccga
      361 tatacaaaat tacaatctct attccagtaa tacggtgcgc accatccagt cggcaacct
//
LOCUS       DAJVBX010000431         3155 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.guided.293, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000431 DAJVBX010000000
VERSION     DAJVBX010000431.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 3155)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3155)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3155
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.guided.293"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            316..774
                     /gene="gpt"
                     /locus_tag="OPV72_004548"
     CDS             316..774
                     /gene="gpt"
                     /locus_tag="OPV72_004548"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HCR9916650.1"
                     /translation="MSEKYVVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGA
                     LLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIRE
                     MYPKAHFVTIFAKPAGRPLVDDYVIDIPQNTWIEQPWDMGVVFVPPISGR"
     gene            863..2107
                     /gene="frsA"
                     /locus_tag="OPV72_004549"
     CDS             863..2107
                     /gene="frsA"
                     /locus_tag="OPV72_004549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase FrsA"
                     /protein_id="HCR9916651.1"
                     /translation="MTQANLSETLFKPRFKHTETSTLVRRFNRGSQPPMQSALDGKNV
                     PHWYRMINRLMWIWRGVDPREILDVQARIVMSDAERTDDDLYDTVIGYRGGNWIYEWA
                     KQAMDWQQKACQEQDAMRSGRYWLHASTLYNIAAYPHLKGDELAEQAQALANRAYEEA
                     AQRLPGSLREMEFAVPGGSPVTAFLHMPKGDGPFPTVLMCGGLDAMQIDYYTLYERYF
                     APRGIAMLTLDMPSVGFSSKWKLTQDSSLLHQHVLKALPNVPWVDHTRVAAFGFRFGA
                     NVAVRLAYLEAPRLKAVACLGPVVHALLSDPQRQSTVPEMYLDVLASRLGMHDASDEA
                     LRVELNRYSLKVQGLLGRRCPTPMLSGFWKNDPFSPEEESRLITTSSSDGKLIEIPFN
                     PVYRNFDHALQEITDWINHRLC"
     gene            2165..2566
                     /gene="crl"
                     /locus_tag="OPV72_004550"
     CDS             2165..2566
                     /gene="crl"
                     /locus_tag="OPV72_004550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-binding protein Crl"
                     /protein_id="HCR9916652.1"
                     /translation="MTLPSGHPKSRLIKKFTALGPYIREGQCEDNRFFFDCLAVCVNV
                     KPAPEKREFWGWWMELEAQEKRFTYRYQFGLFDKEGNWTVVPINETEVVERLEYTLRE
                     FHEKLRDLLISMELALEPSDDFNDEPVKLSA"
     gene            complement(2617..>3155)
                     /locus_tag="OPV72_004551"
     CDS             complement(2617..>3155)
                     /locus_tag="OPV72_004551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="porin"
                     /protein_id="HCR9916653.1"
                     /translation="GKNEDRDVKKQNGDGFGTSVSYDFGGSDFAVSGAYTLSDRTREQ
                     NLQRRGTGDKAEAWATGVKYDANDIYIATFYSETRNMTPVSGGFANKTQNFEAVIQYQ
                     FDFGLRPSLGYVLSKGKDIEGVGSEDLVNYIDVGAIYYFNKNMSAFVDYKINQLDSDN
                     TLGINDDDIVAIGLTYQF"
BASE COUNT          764 a          782 c          831 g          778 t
ORIGIN      
        1 gaatagaaca gattttggca aaaatatccc acaaaggttg tggtgataac tgagacagtt
       61 cagacacgat aagtctcctt ggcggtggtc tgaaaaacgt tcttacaggc cacagggtta
      121 gcggaattaa taactcttac gagatgcgac tgagaatacc actttctccg cctgcgggta
      181 gtataaagca tacaaaaaga ggcgtggatt ccgctaaaca ctggttttta gcgcgtcagg
      241 tctctataat ctcgcgcaac tatttccccc tcgaacactt tttaagccgt agataaacag
      301 gctgggacac ttcacatgag cgaaaaatac gtcgtcacct gggacatgtt gcagattcac
      361 gcacgcaaac tggcgagccg cctcatgcct tcagaacaat ggaaaggcat tattgccgta
      421 agtcgtggcg gccttgtacc gggcgcacta ctggcgcgtg aattgggcat tcgtcatgtc
      481 gataccgtat gcatctccag ctacgatcac gataaccagc gcgaactgaa agtgctgaaa
      541 cgtgcagaag gcgatggcga aggctttatc gtcatcgacg atctggtcga taccggcggc
      601 accgccgtcg cgattcgcga aatgtaccct aaagcgcatt tcgtcacgat tttcgctaaa
      661 ccggcgggcc gtccgctggt tgatgattat gttattgata ttcctcagaa cacctggatt
      721 gagcagccct gggatatggg tgtggtattt gtaccgccga tttcaggtcg ttaatcagca
      781 gcttttcaga gcgcccggca atgccgggcg ctgttttatt ggttacaata agcctctatg
      841 agtatccaag gaggctgcac gaatgacaca ggctaacctc agcgaaaccc tgttcaaacc
      901 ccgctttaaa catactgaaa cgtctaccct tgtccgtcgg ttcaatcgtg ggtcgcagcc
      961 gcccatgcaa tccgcgctgg acggtaagaa cgtcccgcat tggtatcgca tgataaaccg
     1021 cctgatgtgg atttggcgcg gcgttgaccc acgagaaatc cttgatgtgc aggcgcgcat
     1081 tgtgatgagc gacgcagagc gaacggatga tgatttatac gatacggtca tcggttaccg
     1141 cggcggcaac tggatttatg agtgggcaaa gcaggcgatg gactggcagc agaaagcctg
     1201 tcaggaacag gacgccatgc gcagcggacg ctactggctt catgcctcaa cgctctataa
     1261 cattgccgcc tacccgcatt tgaagggcga tgagctggcg gagcaggcgc aggcgctggc
     1321 gaatcgcgcc tatgaagagg ccgcgcagcg gttgccaggc tcgttacgtg aaatggaatt
     1381 tgccgttcct ggcggttcgc ctgtcaccgc gtttttacat atgccgaaag gggatggtcc
     1441 gtttccgacg gtgctcatgt gcggcggcct ggacgccatg caaatcgact attacaccct
     1501 gtatgaacgc tatttcgcgc cgcgcggtat cgcgatgtta acgcttgata tgccttcggt
     1561 tggattttca tcaaagtgga aattaaccca ggattccagc ttgctccacc agcatgtgtt
     1621 aaaagcgctt cctaatgtcc cctgggtgga tcatacccgt gttgcggcgt ttggtttccg
     1681 ttttggcgcc aacgttgcgg tgcgtctggc ctatctggaa gcgccgcgtt tgaaagcggt
     1741 ggcttgcctg gggccggtgg tccatgcgct acttagcgat ccgcaacgac agagcacagt
     1801 gccggagatg tatctggatg tgctggccag ccgtctgggt atgcatgatg cttcggatga
     1861 ggcgctgcgt gtggagctca accgctattc gttgaaagta caggggctac tgggcagacg
     1921 ttgtcctacg ccaatgcttt ccggcttctg gaaaaacgat cctttcagcc cggaagaaga
     1981 gtctcgctta attacaacat catcttcaga cggtaagctg atagagatcc cttttaaccc
     2041 ggtgtaccgc aattttgacc acgcgctgca agaaattacc gactggatta atcatagatt
     2101 gtgttaatag attgataaat tctattgatt tggtaaaaca gttgcttcat taaaggagat
     2161 cgcaataacg ttaccgagtg gacacccgaa aagtagattg atcaagaaat ttaccgcgct
     2221 tggcccctat atccgggaag ggcagtgcga agacaatcgt ttttttttcg attgcctggc
     2281 agtttgcgtc aacgtgaagc ccgcgccaga gaagcgtgaa ttttggggct ggtggatgga
     2341 gctggaagca caagagaaac gcttcactta tcgttatcag tttggtttgt ttgataaaga
     2401 gggcaactgg accgtagtgc cgattaacga aaccgaagtg gtggagcgac tggaatacac
     2461 gctacgcgag tttcatgaaa agctacgcga cctgctgatt tctatggagc tggcgctgga
     2521 gccgtctgac gatttcaacg acgagccggt aaaactgtcg gcataaccct gctgccatgc
     2581 ctgatggcgt agcgccatca ggcacaatgc gacttatcag aactggtagg tcaaccctat
     2641 tgccacaata tcatcgtcat taatgcctaa cgtgttatcg ctatcaagct gattgatttt
     2701 gtaatctaca aacgcggaca tatttttgtt gaaataatag attgcgccaa cgtcaatgta
     2761 attcaccaaa tcctcactgc cgacgccctc aatatctttg ccttttgaca gcacatagcc
     2821 taatgacgga cgcagaccaa agtcaaactg atactggata accgcttcga agttttgagt
     2881 tttattggca aatccgccgg aaactggcgt catgttgcgg gtttctgaat agaaagtcgc
     2941 aatataaata tcattcgcgt catacttaac acccgtagcc caggcttcgg ctttatcgcc
     3001 cgtaccgcgg cgctgcagat tttgctccct ggtgcgatcg gagagagtat aagcgccgct
     3061 gacggcaaaa tcactgccgc cgaaatcata gctcacggaa gtgccgaagc cgtcgccgtt
     3121 ttgctttttc acatcgcgat cttcgttttt cccct
//
LOCUS       DAJVBX010000432         1820 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.guided.329, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000432 DAJVBX010000000
VERSION     DAJVBX010000432.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1820)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1820)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1820
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.guided.329"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            complement(<1..782)
                     /locus_tag="OPV72_004552"
     CDS             complement(<1..782)
                     /locus_tag="OPV72_004552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCR9916654.1"
                     /translation="MNLLQMDMNLLKVLYVLLETSSTGKTAQKLALSPSAVSHALMRL
                     RDALNDPLFRREGNRQIATPYAQALRDKLAPVFVSLNEELFGDKENGSRCFRVVLPPA
                     LNALLTPVLAEKGHLHQAVIECLPFARRPWRDELLDSSVDLVLAIGDHQKQVSALHYE
                     RVGTTRLIAVYGAPLRSRLENAAALNFADLQHYQHIYCLPWTKENNELDRQQARAGFE
                     RPLAFVCHDYSQLAPAVQSAPLMAIVPRPWYENLSDKRGLFVL"
     gene            856..1740
                     /locus_tag="OPV72_004553"
     CDS             856..1740
                     /locus_tag="OPV72_004553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HARLDQ motif MBL-fold protein"
                     /protein_id="HCR9916655.1"
                     /translation="MNRYVLFFVCIFSTSALPAMAALDPSQPLSPAPPLSLFKAWAKP
                     MKPFQITEGVWYVGTENLSSILLTTPAGHILIDAGLDESAPQIKANIEAAGFRFTDVR
                     YLLSSHARLDQAGGMARLKAWSGAQLVASQPNADQMARGGRQDFALGDALPFPLVTTD
                     KIIHNQESISLGGVTVTALFTPGHLPGSTSWRVTLRNGKTLIYADSLATPDYLLINNK
                     NYPDLVTDIQSSFKTLAAQHVDIFIANKGDRFGLLEKRQQLRNGDTQAFFDSNGLQQY
                     VERSRQRFITQLTAQQPQ"
BASE COUNT          478 a          510 c          432 g          400 t
ORIGIN      
        1 aggacaaaaa gaccgcgctt atcggataaa ttttcatacc aggggcgcgg tacaatcgcc
       61 attagcggcg ccgactggac agcaggcgca agttgactgt aatcatgaca aacaaacgcc
      121 aacggacgtt caaacccggc acgagcctgc tgcctgtcca gttcgttgtt ctcttttgtc
      181 cacggcaaac agtaaatgtg ttgataatgc tgcagatcag caaaattcaa cgctgcggca
      241 ttctccagac gtgaacgcaa tggcgcgcca taaaccgcga tcaaacgcgt cgtccccacc
      301 cgctcgtaat gcagagcgct gacctgcttt tgatggtcgc caattgccag caccaaatca
      361 accgagctat ccaacagttc atcacgccag ggtcggcggg caaaaggaag gcactcgatc
      421 accgcctgat gaagatgacc tttctctgcg agaacgggcg taagcagcgc gttcaatgcg
      481 ggaggaagta ccacccggaa acaacgggag ccgttctctt tatcgccaaa cagctcctca
      541 ttaagcgaaa caaacacagg cgccaacttg tcacgcagcg cctgcgcata aggcgtagca
      601 atctggcggt tcccctcccg tcgaaacaac ggatcgttta gcgcatcgcg caatctcatt
      661 agcgcatgac tcaccgcaga aggcgacaaa gccagctttt gcgccgtttt ccccgtagag
      721 ctcgtctcca gcagcacata cagtactttt aacaggttca tatccatttg cagcaagttc
      781 attaaacgtc tctcttattg aacctgacta aattactgcc aggtatactg cgggcgcttc
      841 aatcaggaga acattatgaa tcgctatgta ttattctttg tatgtatatt ttcaacatca
      901 gcacttcctg ccatggcggc attagatcct tcacaaccgt tatcacccgc gcctccgtta
      961 tcactgttta aagcgtgggc taagcctatg aagccgtttc aaatcacaga aggcgtgtgg
     1021 tatgtcggta cggaaaatct ctcttctatt ctgctgacca ctccggcagg gcatattctt
     1081 attgatgcgg ggctggatga aagcgcaccg caaattaaag cgaatattga agcggcagga
     1141 tttcgcttca ctgacgtgcg ctatctgttg agcagccatg cgcggctgga tcaagcgggg
     1201 ggcatggcac gtttgaaagc gtggagcggc gcacaattgg tcgccagtca acccaacgcc
     1261 gatcagatgg cgaggggtgg acgacaggat tttgcgcttg gcgatgcgct ccccttcccg
     1321 ctcgtcacca ctgataaaat tatccacaac caggaaagca tcagcctcgg aggggtaacc
     1381 gtgacagcac tattcacgcc tggacatctg cccggctcaa cctcctggcg cgtaacgctc
     1441 cgcaacggca agacgctaat ttacgcagat agtctcgcca cacctgacta tctgctgatt
     1501 aacaacaaaa attaccctga cctggttact gatattcaga gcagctttaa aacactggcc
     1561 gcccagcatg ttgatatctt tattgccaac aaaggtgacc gcttcgggct actggagaaa
     1621 cgacagcaac ttcgcaacgg cgatacacag gcattctttg attccaatgg cttgcaacag
     1681 tatgtggaac gctcgcgtca gcgcttcatc acacaactta ccgcacagca gccacaatga
     1741 aatgactcac cggcggcgcg tccagggcgc cgttcaggta atttatctaa gtcaaaacag
     1801 aaaaacctcg tatacaataa
//
LOCUS       DAJVBX010000433         1483 bp    DNA     linear   BCT 08-NOV-2022
DEFINITION  TPA_asm: Salmonella enterica subsp. enterica serovar Typhi isolate
            COL_INS_S_Ty1335_1081_15 SAMEA7993261-rid15832823.guided.349, whole
            genome shotgun sequence.
ACCESSION   DAJVBX010000433 DAJVBX010000000
VERSION     DAJVBX010000433.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA7993261
            Sequence Read Archive: ERR5243647
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Salmonella enterica subsp. enterica serovar Typhi (Salmonella
            typhi)
  ORGANISM  Salmonella enterica subsp. enterica serovar Typhi
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Salmonella.
REFERENCE   1  (bases 1 to 1483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001481007.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001481007.1
            Genome Coverage       :: 45x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/08/2022 20:09:00
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,555
            CDSs (total)                      :: 4,475
            Genes (coding)                    :: 4,229
            CDSs (with protein)               :: 4,229
            Genes (RNA)                       :: 80
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 68
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 246
            CDSs (without protein)            :: 246
            Pseudo Genes (ambiguous residues) :: 0 of 246
            Pseudo Genes (frameshifted)       :: 130 of 246
            Pseudo Genes (incomplete)         :: 70 of 246
            Pseudo Genes (internal stop)      :: 86 of 246
            Pseudo Genes (multiple problems)  :: 35 of 246
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1483
                     /organism="Salmonella enterica subsp. enterica serovar
                     Typhi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA7993261-rid15832823.guided.349"
                     /serovar="Typhi"
                     /isolate="COL_INS_S_Ty1335_1081_15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /sub_species="enterica"
                     /db_xref="taxon:90370"
                     /country="Colombia"
                     /collection_date="2015"
     gene            11..409
                     /gene="aac(6')"
                     /locus_tag="OPV72_004554"
                     /pseudo
     CDS             11..409
                     /gene="aac(6')"
                     /locus_tag="OPV72_004554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004874306.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cryptic aminoglycoside N-acetyltransferase
                     AAC(6')-Iy/Iaa"
     gene            complement(473..>1483)
                     /locus_tag="OPV72_004555"
     CDS             complement(473..>1483)
                     /locus_tag="OPV72_004555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HCR9916656.1"
                     /translation="EDENNLRSNTESFDKKYIMPRVLQGIELKEIDLSTQLLGIPLKT
                     PIIQAPMAAQGLAHASGELATAKGMAQVGSIFSLSTYGNKTIEEVANVSGKNPFFFQL
                     YMSKNNQFNEFILAQAVKHGAKAIILTVDSPVGGYREEDIKNNFQFPLSFANLEMFAR
                     KNDDGSKTGKGAGISEIYAQAKQAFTPEDIAYVHRISGLPVIVKGIQSPEDAEIAIQA
                     GAAGIWVSNHGGRQLDSGPSSFDMLPAIAKVVNKRVPVIFDSGVRRGSHVFKALASGA
                     DIVAVGRPVLYGLNLGGAQGVASVIEQLNKELTINMMLGGARNIEQVKTTRLLTEKDL
                     PQ"
BASE COUNT          368 a          381 c          342 g          392 t
ORIGIN      
        1 caaaacccat ctggagcact ggcgcggatt gcgaaaacag ctctggcctg gtcacccgga
       61 tgacgcccat ctggcggacg gcgaagaaat tctgcaagcc gaacatctgg catcatttat
      121 tgcgatggca gacggggtgg cgattggctt tgcggatgcc tcaatccgcc acgattatgt
      181 caatggctgt gacagttcgc ccgtggtttt ccttgaaggt atttttgttc tcccctcgtt
      241 ccgtcaacgc ggcttagcga aacaattgat agcagcagtg caacgatggg gaacgaataa
      301 agggtgtcgg gaaatggctt ccgatacctc gccggaaaat acaatttcac agaaagttca
      361 cctggcgtta ggatttgagg aaacagagcg cgtcattttc taccgaaagc gttgtcgagg
      421 aaaatcacac aggaaaaggt cgggtataat acccgacctc tatattactg tattactgtg
      481 gcagatcttt ttcagttaac aagcgtgtcg ttttcacttg ttcaatattc ctggcgccac
      541 ccaacatcat gttaattgtc agctctttgt ttagctgttc aatcactgat gccacaccct
      601 gagcgccgcc aagattaaga ccgtataata caggtcggcc aaccgccaca atatccgccc
      661 cgctggctaa cgccttgaat acgtgcgaac cacggcgtac tccactgtca aaaataacag
      721 gcactcgctt gttgacgact tttgcaatcg caggaagcat atcgaatgag gacggcccgc
      781 tgtctaattg acggccacca tgattagaaa cccatattcc tgcggcccca gcctggatag
      841 caatttcagc atcctccggc gactgaatgc cttttacaat aaccggcaga ccggaaatac
      901 gatgtacata ggcaatatcc tccggcgtaa aggcttgttt agcctgcgcg taaatttcac
      961 ttatccctgc ccctttgccg gtttttgaac catcgtcatt tttcctggcg aacatttcca
     1021 ggtttgcaaa actcagcggg aactggaagt tatttttaat atcttcttcc cgataaccgc
     1081 cgacaggtga atctacggtc agaataatcg ctttagcgcc atgttttacc gcttgtgcaa
     1141 gaataaattc gttaaattga ttattcttac tcatataaag ctggaagaag aacgggtttt
     1201 tcccggaaac gttagccacc tcttcgatgg tcttgttgcc ataagtgctc aacgagaaaa
     1261 tcgaaccgac ctgcgccatg cctttcgccg tcgccaactc tccggaggcg tgggccaggc
     1321 cctgcgccgc catcggtgcc tggattatag gcgttttaag cggaataccc agtagctgcg
     1381 ttgataaatc gatctctttt aactcaatgc cctgtaatac gcgcggcata atatattttt
     1441 tgtcaaagct ttcggtgttg ctgcgaaggt tattctcatc ttc
//
